ID   1433B_HUMAN             Reviewed;         246 AA.
AC   P31946; A8K9K2; E1P616;
DE   RecName: Full=14-3-3 protein beta/alpha;
DE   AltName: Full=Protein 1054;
DE   AltName: Full=Protein kinase C inhibitor protein 1;
DE            Short=KCIP-1;
DE   Contains:
DE     RecName: Full=14-3-3 protein beta/alpha, N-terminally processed;
GN   Name=YWHAB;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0050815; F:phosphoserine binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051220; P:cytoplasmic sequestering of protein; IDA:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0035308; P:negative regulation of protein dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   1433E_HUMAN             Reviewed;         255 AA.
AC   P62258; B3KY71; D3DTH5; P29360; P42655; Q4VJB6; Q53XZ5; Q63631;
AC   Q7M4R4;
DE   RecName: Full=14-3-3 protein epsilon;
DE            Short=14-3-3E;
GN   Name=YWHAE;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0050815; F:phosphoserine binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0086013; P:membrane repolarization during cardiac muscle cell action potential; IC:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:1902309; P:negative regulation of peptidyl-serine dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IC:BHF-UCL.
DR   GO; GO:0003064; P:regulation of heart rate by hormone; NAS:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1433F_HUMAN             Reviewed;         246 AA.
AC   Q04917;
DE   RecName: Full=14-3-3 protein eta;
DE   AltName: Full=Protein AS1;
GN   Name=YWHAH; Synonyms=YWHA1;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0035259; F:glucocorticoid receptor binding; IPI:UniProtKB.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; ISS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006713; P:glucocorticoid catabolic process; IDA:UniProtKB.
DR   GO; GO:0042921; P:glucocorticoid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0050774; P:negative regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IDA:BHF-UCL.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   1433G_HUMAN             Reviewed;         247 AA.
AC   P61981; O70457; P35214; Q6FH52; Q9UDP2; Q9UN99;
DE   RecName: Full=14-3-3 protein gamma;
DE   AltName: Full=Protein kinase C inhibitor protein 1;
DE            Short=KCIP-1;
DE   Contains:
DE     RecName: Full=14-3-3 protein gamma, N-terminally processed;
GN   Name=YWHAG;
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0008426; F:protein kinase C inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; NAS:GOC.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IMP:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IMP:UniProtKB.
//
ID   1433S_HUMAN             Reviewed;         248 AA.
AC   P31947; Q6FH30; Q6FH51; Q96DH0;
DE   RecName: Full=14-3-3 protein sigma;
DE   AltName: Full=Epithelial cell marker protein 1;
DE   AltName: Full=Stratifin;
GN   Name=SFN; Synonyms=HME1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008426; F:protein kinase C inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:HGNC.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:ProtInc.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; TAS:GOC.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:HGNC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   1433T_HUMAN             Reviewed;         245 AA.
AC   P27348; D6W4Z5; Q567U5; Q5TZU8; Q9UP48;
DE   RecName: Full=14-3-3 protein theta;
DE   AltName: Full=14-3-3 protein T-cell;
DE   AltName: Full=14-3-3 protein tau;
DE   AltName: Full=Protein HS1;
GN   Name=YWHAQ;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   1433Z_HUMAN             Reviewed;         245 AA.
AC   P63104; A8K1N0; B7Z465; P29213; P29312; Q32P43; Q5XJ08; Q6GPI2;
AC   Q6IN74; Q6NUR9; Q6P3U9; Q86V33;
DE   RecName: Full=14-3-3 protein zeta/delta;
DE   AltName: Full=Protein kinase C inhibitor protein 1;
DE            Short=KCIP-1;
GN   Name=YWHAZ;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0002553; P:histamine secretion by mast cell; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   1A01_HUMAN              Reviewed;         365 AA.
AC   P30443; O77964; O78171; Q9MYA3; Q9TP25; Q9TQP5;
DE   RecName: Full=HLA class I histocompatibility antigen, A-1 alpha chain;
DE   AltName: Full=MHC class I antigen A*1;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016045; P:detection of bacterium; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IMP:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:UniProt.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A02_HUMAN              Reviewed;         365 AA.
AC   P01892; O19619; P06338; P10313; P30444; P30445; P30446; P30514;
AC   Q29680; Q29837; Q29899; Q95352; Q95380; Q9TPX8; Q9TPX9; Q9TPY0;
AC   Q9TQH5; Q9TQI3;
DE   RecName: Full=HLA class I histocompatibility antigen, A-2 alpha chain;
DE   AltName: Full=MHC class I antigen A*2;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0002486; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:UniProt.
DR   GO; GO:2000568; P:positive regulation of memory T cell activation; IDA:UniProt.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:UniProt.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   1A03_HUMAN              Reviewed;         365 AA.
AC   P04439; O19546; O19756; Q65A82; Q9GJE6; Q9GJE7; Q9GJE8; Q9MYE6;
AC   Q9MYG4; Q9TPR8;
DE   RecName: Full=HLA class I histocompatibility antigen, A-3 alpha chain;
DE   AltName: Full=MHC class I antigen A*3;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A11_HUMAN              Reviewed;         365 AA.
AC   P13746; O19605; O19606; Q29747; Q29835; Q5S3G1; Q9BCN0; Q9MYI5;
AC   Q9TQE9; Q9TQP6; Q9TQP7;
DE   RecName: Full=HLA class I histocompatibility antigen, A-11 alpha chain;
DE   AltName: Full=MHC class I antigen A*11;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A1L1_HUMAN             Reviewed;         501 AA.
AC   Q96QU6; Q8WUL4; Q96LX5;
DE   RecName: Full=1-aminocyclopropane-1-carboxylate synthase-like protein 1;
DE            Short=ACC synthase-like protein 1;
GN   Name=ACCS; Synonyms=PHACS;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; NAS:UniProtKB.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
//
ID   1A1L2_HUMAN             Reviewed;         568 AA.
AC   Q4AC99;
DE   RecName: Full=Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2;
DE            Short=ACC synthase-like protein 2;
GN   Name=ACCSL;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
//
ID   1A23_HUMAN              Reviewed;         365 AA.
AC   P30447; Q9TQF1; Q9TQF8; Q9TQG5; Q9TQM6;
DE   RecName: Full=HLA class I histocompatibility antigen, A-23 alpha chain;
DE   AltName: Full=HLA class I histocompatibility antigen, A-9 alpha chain;
DE   AltName: Full=MHC class I antigen A*23;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A24_HUMAN              Reviewed;         365 AA.
AC   P05534; P30448; P30449; Q29908; Q29909; Q29910; Q95355;
DE   RecName: Full=HLA class I histocompatibility antigen, A-24 alpha chain;
DE   AltName: Full=Aw-24;
DE   AltName: Full=HLA class I histocompatibility antigen, A-9 alpha chain;
DE   AltName: Full=MHC class I antigen A*24;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A25_HUMAN              Reviewed;         365 AA.
AC   P18462; Q95362; Q9TQE8; Q9TQG0; Q9UQU3;
DE   RecName: Full=HLA class I histocompatibility antigen, A-25 alpha chain;
DE   AltName: Full=HLA class I histocompatibility antigen, A-10 alpha chain;
DE   AltName: Full=MHC class I antigen A*25;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A26_HUMAN              Reviewed;         365 AA.
AC   P30450; O02963; O78073; P79563; Q30208; Q31623; Q95377; Q9BD15;
AC   Q9BD19; Q9MW42; Q9TQK5;
DE   RecName: Full=HLA class I histocompatibility antigen, A-26 alpha chain;
DE   AltName: Full=MHC class I antigen A*26;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A30_HUMAN              Reviewed;         365 AA.
AC   P16188; O19598; O62921; P30452; Q9UIP7;
DE   RecName: Full=HLA class I histocompatibility antigen, A-30 alpha chain;
DE   AltName: Full=MHC class I antigen A*30;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A29_HUMAN              Reviewed;         365 AA.
AC   P30512; O02955; O19687; O98011; P30451; P79562;
DE   RecName: Full=HLA class I histocompatibility antigen, A-29 alpha chain;
DE   AltName: Full=Aw-19;
DE   AltName: Full=MHC class I antigen A*29;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A31_HUMAN              Reviewed;         365 AA.
AC   P16189; O62924; O98009; O98137; Q8MHM1; Q9TPQ3; Q9TQ24; Q9UQU6;
AC   Q9UQU7;
DE   RecName: Full=HLA class I histocompatibility antigen, A-31 alpha chain;
DE   AltName: Full=MHC class I antigen A*31;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A32_HUMAN              Reviewed;         365 AA.
AC   P10314; O77937; Q29838; Q8MHN9; Q9MYE9; Q9MYG5; Q9TQF5; Q9TQF9;
DE   RecName: Full=HLA class I histocompatibility antigen, A-32 alpha chain;
DE   AltName: Full=MHC class I antigen A*32;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A33_HUMAN              Reviewed;         365 AA.
AC   P16190; O02939; O02954;
DE   RecName: Full=HLA class I histocompatibility antigen, A-33 alpha chain;
DE   AltName: Full=Aw-19;
DE   AltName: Full=Aw-33;
DE   AltName: Full=MHC class I antigen A*33;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A34_HUMAN              Reviewed;         365 AA.
AC   P30453; P30454;
DE   RecName: Full=HLA class I histocompatibility antigen, A-34 alpha chain;
DE   AltName: Full=Aw-34;
DE   AltName: Full=HLA class I histocompatibility antigen, A-10 alpha chain;
DE   AltName: Full=MHC class I antigen A*34;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A36_HUMAN              Reviewed;         365 AA.
AC   P30455; Q9MY89;
DE   RecName: Full=HLA class I histocompatibility antigen, A-36 alpha chain;
DE   AltName: Full=Aw-36;
DE   AltName: Full=MHC class I antigen A*36;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A43_HUMAN              Reviewed;         365 AA.
AC   P30456; O19509;
DE   RecName: Full=HLA class I histocompatibility antigen, A-43 alpha chain;
DE   AltName: Full=Aw-43;
DE   AltName: Full=MHC class I antigen A*43;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A66_HUMAN              Reviewed;         365 AA.
AC   P30457; P30458;
DE   RecName: Full=HLA class I histocompatibility antigen, A-66 alpha chain;
DE   AltName: Full=Aw-66;
DE   AltName: Full=HLA class I histocompatibility antigen, A-10 alpha chain;
DE   AltName: Full=MHC class I antigen A*66;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A68_HUMAN              Reviewed;         365 AA.
AC   P01891; O19673; O19695; O19794; O19795; O43907; O77938; O98010;
AC   P10315; P79505; Q9MYA5; Q9MYC4; Q9TQG7; Q9TQN5; Q9UIN2;
DE   RecName: Full=HLA class I histocompatibility antigen, A-68 alpha chain;
DE   AltName: Full=Aw-68;
DE   AltName: Full=HLA class I histocompatibility antigen, A-28 alpha chain;
DE   AltName: Full=MHC class I antigen A*68;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A69_HUMAN              Reviewed;         365 AA.
AC   P10316; B1PKZ3;
DE   RecName: Full=HLA class I histocompatibility antigen, A-69 alpha chain;
DE   AltName: Full=Aw-69;
DE   AltName: Full=HLA class I histocompatibility antigen, A-28 alpha chain;
DE   AltName: Full=MHC class I antigen A*69;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A74_HUMAN              Reviewed;         365 AA.
AC   P30459; O19647; O43906; O46874; Q95IZ5; Q9UIN1;
DE   RecName: Full=HLA class I histocompatibility antigen, A-74 alpha chain;
DE   AltName: Full=Aw-19;
DE   AltName: Full=Aw-74;
DE   AltName: Full=MHC class I antigen A*74;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1A80_HUMAN              Reviewed;         365 AA.
AC   Q09160;
DE   RecName: Full=HLA class I histocompatibility antigen, A-80 alpha chain;
DE   AltName: Full=Aw-80;
DE   AltName: Full=HLA class I histocompatibility antigen, A-1 alpha chain;
DE   AltName: Full=MHC class I antigen A*80;
DE   Flags: Precursor;
GN   Name=HLA-A; Synonyms=HLAA;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B07_HUMAN              Reviewed;         362 AA.
AC   P01889; Q29638; Q29681; Q29854; Q29861; Q31613; Q5SRJ2; Q9GIX1;
AC   Q9TP95;
DE   RecName: Full=HLA class I histocompatibility antigen, B-7 alpha chain;
DE   AltName: Full=MHC class I antigen B*7;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:2001198; P:regulation of dendritic cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0032655; P:regulation of interleukin-12 production; IMP:BHF-UCL.
DR   GO; GO:0032675; P:regulation of interleukin-6 production; IMP:BHF-UCL.
DR   GO; GO:0002667; P:regulation of T cell anergy; IMP:BHF-UCL.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B08_HUMAN              Reviewed;         362 AA.
AC   P30460; O62901; O95730; O98140; P79542; Q95369; Q95J00; Q9GJ20;
AC   Q9MY78; Q9MYF4; Q9TQH6; Q9TQM2; Q9UQT0;
DE   RecName: Full=HLA class I histocompatibility antigen, B-8 alpha chain;
DE   AltName: Full=MHC class I antigen B*8;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B13_HUMAN              Reviewed;         362 AA.
AC   P30461; O02956; O78180; Q29661; Q29933; Q9GIY5;
DE   RecName: Full=HLA class I histocompatibility antigen, B-13 alpha chain;
DE   AltName: Full=MHC class I antigen B*13;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:UniProt.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B14_HUMAN              Reviewed;         362 AA.
AC   P30462; O02862; P30463;
DE   RecName: Full=HLA class I histocompatibility antigen, B-14 alpha chain;
DE   AltName: Full=MHC class I antigen B*14;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B15_HUMAN              Reviewed;         362 AA.
AC   P30464; B0V0B8; P30465; P30513; Q29633; Q29636; Q29829; Q29953;
AC   Q29982; Q95343; Q95344; Q9BD06;
DE   RecName: Full=HLA class I histocompatibility antigen, B-15 alpha chain;
DE   AltName: Full=MHC class I antigen B*15;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B18_HUMAN              Reviewed;         362 AA.
AC   P30466; O62897; Q29845; Q5JP37; Q9BCM6; Q9GJ23; Q9MY84; Q9MYC7;
AC   Q9TP37; Q9TQH7;
DE   RecName: Full=HLA class I histocompatibility antigen, B-18 alpha chain;
DE   AltName: Full=MHC class I antigen B*18;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B27_HUMAN              Reviewed;         362 AA.
AC   P03989; O19692; P10317; P10318; P19373; P30467; Q08136; Q29693;
AC   Q29846; Q29961;
DE   RecName: Full=HLA class I histocompatibility antigen, B-27 alpha chain;
DE   AltName: Full=MHC class I antigen B*27;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; IDA:UniProt.
DR   GO; GO:0002486; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
DR   GO; GO:0016045; P:detection of bacterium; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IMP:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B35_HUMAN              Reviewed;         362 AA.
AC   P30685; O62919; P30468; P30469; P30470; P30471; P30472; P30473;
AC   P30474; Q9GJM7; Q9TPV2; Q9TQH3; Q9TQH9; Q9TQN4; Q9TQN6;
DE   RecName: Full=HLA class I histocompatibility antigen, B-35 alpha chain;
DE   AltName: Full=MHC class I antigen B*35;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B37_HUMAN              Reviewed;         362 AA.
AC   P18463; O19627; Q546L8; Q95HA3; Q95HA8; Q95HM9; Q9GJ31;
DE   RecName: Full=HLA class I histocompatibility antigen, B-37 alpha chain;
DE   AltName: Full=MHC class I antigen B*37;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:UniProt.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B38_HUMAN              Reviewed;         362 AA.
AC   Q95365; O19779; O77959; O78160; Q29935; Q29936; Q95IB8; Q95IH5;
AC   Q9BCM8; Q9MY92; Q9MYG1; Q9TPT2;
DE   RecName: Full=HLA class I histocompatibility antigen, B-38 alpha chain;
DE   AltName: Full=Bw-4;
DE   AltName: Full=MHC class I antigen B*38;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B40_HUMAN              Reviewed;         362 AA.
AC   Q04826; O19556; O19651; P01890; P30477; P30478; Q29762; Q29842;
AC   Q29855; Q30173; Q31603; Q9TPT6;
DE   RecName: Full=HLA class I histocompatibility antigen, B-40 alpha chain;
DE   AltName: Full=Bw-60;
DE   AltName: Full=MHC class I antigen B*40;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B39_HUMAN              Reviewed;         362 AA.
AC   P30475; O02960; O78217; P30476; P79504; Q29665; Q29697; Q29749;
AC   Q29847; Q29852; Q29858; Q8HWF0; Q9TPQ7;
DE   RecName: Full=HLA class I histocompatibility antigen, B-39 alpha chain;
DE   AltName: Full=MHC class I antigen B*39;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B41_HUMAN              Reviewed;         362 AA.
AC   P30479; O19595; Q29848; Q5TK77; Q9MY79; Q9MY94;
DE   RecName: Full=HLA class I histocompatibility antigen, B-41 alpha chain;
DE   AltName: Full=Bw-41;
DE   AltName: Full=MHC class I antigen B*41;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B42_HUMAN              Reviewed;         362 AA.
AC   P30480; P79555;
DE   RecName: Full=HLA class I histocompatibility antigen, B-42 alpha chain;
DE   AltName: Full=MHC class I antigen B*42;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B44_HUMAN              Reviewed;         362 AA.
AC   P30481; P10320; P30482; P79524; Q29850; Q5RIP1; Q860I4; Q861B5;
AC   Q9BCM7; Q9MYC3; Q9UQS8;
DE   RecName: Full=HLA class I histocompatibility antigen, B-44 alpha chain;
DE   AltName: Full=Bw-44;
DE   AltName: Full=MHC class I antigen B*44;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B45_HUMAN              Reviewed;         362 AA.
AC   P30483; Q9GIZ0; Q9MX21;
DE   RecName: Full=HLA class I histocompatibility antigen, B-45 alpha chain;
DE   AltName: Full=Bw-45;
DE   AltName: Full=MHC class I antigen B*45;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B46_HUMAN              Reviewed;         362 AA.
AC   P30484; Q9TPR2;
DE   RecName: Full=HLA class I histocompatibility antigen, B-46 alpha chain;
DE   AltName: Full=Bw-46;
DE   AltName: Full=MHC class I antigen B*46;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B47_HUMAN              Reviewed;         362 AA.
AC   P30485; O19555; O77933; Q95392; Q9GIL3;
DE   RecName: Full=HLA class I histocompatibility antigen, B-47 alpha chain;
DE   AltName: Full=Bw-47;
DE   AltName: Full=MHC class I antigen B*47;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B48_HUMAN              Reviewed;         362 AA.
AC   P30486; Q29764;
DE   RecName: Full=HLA class I histocompatibility antigen, B-48 alpha chain;
DE   AltName: Full=Bw-48;
DE   AltName: Full=MHC class I antigen B*48;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B49_HUMAN              Reviewed;         362 AA.
AC   P30487; O19625; Q9MY37; Q9MY93;
DE   RecName: Full=HLA class I histocompatibility antigen, B-49 alpha chain;
DE   AltName: Full=HLA class I histocompatibility antigen, B-21 alpha chain;
DE   AltName: Full=MHC class I antigen B*49;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B50_HUMAN              Reviewed;         362 AA.
AC   P30488; O19615; O19624; O19641; O19783; O46702; O78172; Q9TQG1;
DE   RecName: Full=HLA class I histocompatibility antigen, B-50 alpha chain;
DE   AltName: Full=Bw-50;
DE   AltName: Full=HLA class I histocompatibility antigen, B-21 alpha chain;
DE   AltName: Full=MHC class I antigen B*50;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B51_HUMAN              Reviewed;         362 AA.
AC   P18464; O19675; O78173; P30489; Q29851; Q29857; Q96IT9; Q9MY43;
DE   RecName: Full=HLA class I histocompatibility antigen, B-51 alpha chain;
DE   AltName: Full=MHC class I antigen B*51;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; IDA:UniProt.
DR   GO; GO:0002486; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B52_HUMAN              Reviewed;         362 AA.
AC   P30490; Q9MY75; Q9TPT4;
DE   RecName: Full=HLA class I histocompatibility antigen, B-52 alpha chain;
DE   AltName: Full=Bw-52;
DE   AltName: Full=HLA class I histocompatibility antigen, B-5 alpha chain;
DE   AltName: Full=MHC class I antigen B*52;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B53_HUMAN              Reviewed;         362 AA.
AC   P30491; O78053; O78138; Q30198; Q5TK76; Q9BD43; Q9GJF0; Q9MY42;
AC   Q9TP36; Q9TQH8;
DE   RecName: Full=HLA class I histocompatibility antigen, B-53 alpha chain;
DE   AltName: Full=Bw-53;
DE   AltName: Full=MHC class I antigen B*53;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B55_HUMAN              Reviewed;         362 AA.
AC   P30493; O78163; P30494; P79489; P79523; Q8MGQ3; Q9GIZ9; Q9GJ00;
DE   RecName: Full=HLA class I histocompatibility antigen, B-55 alpha chain;
DE   AltName: Full=Bw-55;
DE   AltName: Full=HLA class I histocompatibility antigen, B-12 alpha chain;
DE   AltName: Full=MHC class I antigen B*55;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB; ORFNames=CDABP0067;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B56_HUMAN              Reviewed;         362 AA.
AC   P30495; O19758; P30496; P79490; Q9GIM3; Q9GJ17; Q9TPR4;
DE   RecName: Full=HLA class I histocompatibility antigen, B-56 alpha chain;
DE   AltName: Full=Bw-22;
DE   AltName: Full=Bw-56;
DE   AltName: Full=MHC class I antigen B*56;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B54_HUMAN              Reviewed;         362 AA.
AC   P30492; Q9TPQ9;
DE   RecName: Full=HLA class I histocompatibility antigen, B-54 alpha chain;
DE   AltName: Full=Bw-22;
DE   AltName: Full=Bw-54;
DE   AltName: Full=MHC class I antigen B*54;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B57_HUMAN              Reviewed;         362 AA.
AC   P18465; O62917; P30497; P79496; Q29679; Q5QT24;
DE   RecName: Full=HLA class I histocompatibility antigen, B-57 alpha chain;
DE   AltName: Full=Bw-57;
DE   AltName: Full=MHC class I antigen B*57;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B58_HUMAN              Reviewed;         362 AA.
AC   P10319; Q29925; Q9TP35; Q9TPS6;
DE   RecName: Full=HLA class I histocompatibility antigen, B-58 alpha chain;
DE   AltName: Full=Bw-58;
DE   AltName: Full=MHC class I antigen B*58;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B59_HUMAN              Reviewed;         362 AA.
AC   Q29940; O02957;
DE   RecName: Full=HLA class I histocompatibility antigen, B-59 alpha chain;
DE   AltName: Full=MHC class I antigen B*59;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B67_HUMAN              Reviewed;         362 AA.
AC   Q29836; Q29678; Q8SNC5; Q95IA6; Q9BD38;
DE   RecName: Full=HLA class I histocompatibility antigen, B-67 alpha chain;
DE   AltName: Full=MHC class I antigen B*67;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B73_HUMAN              Reviewed;         363 AA.
AC   Q31612; G3GN01;
DE   RecName: Full=HLA class I histocompatibility antigen, B-73 alpha chain;
DE   AltName: Full=MHC class I antigen B*73;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B81_HUMAN              Reviewed;         362 AA.
AC   Q31610;
DE   RecName: Full=HLA class I histocompatibility antigen, B-81 alpha chain;
DE   AltName: Full=B'DT;
DE   AltName: Full=MHC class I antigen B*81;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B78_HUMAN              Reviewed;         362 AA.
AC   P30498; O62915; Q29924; Q546M4;
DE   RecName: Full=HLA class I histocompatibility antigen, B-78 alpha chain;
DE   AltName: Full=MHC class I antigen B*78;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1B82_HUMAN              Reviewed;         362 AA.
AC   Q29718; Q29695; Q29742; Q8MHN4; Q9MY61; Q9MYB8;
DE   RecName: Full=HLA class I histocompatibility antigen, B-82 alpha chain;
DE   AltName: Full=MHC class I antigen B*82;
DE   Flags: Precursor;
GN   Name=HLA-B; Synonyms=HLAB;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C01_HUMAN              Reviewed;         366 AA.
AC   P30499; O02865; O19676; P30500; Q29986; Q9UQS9;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-1 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*1;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; IDA:UniProt.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0002486; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C02_HUMAN              Reviewed;         366 AA.
AC   P30501; P30502;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-2 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*2;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C03_HUMAN              Reviewed;         366 AA.
AC   P04222; O62883; O78060; O78068; O78069; P30503; Q29743; Q29992;
AC   Q29993; Q9GIK8; Q9TQB4;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-3 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*3;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C04_HUMAN              Reviewed;         366 AA.
AC   P30504; O78067; O78072; O78090; O78149; Q29921; Q9UM42;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-4 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*4;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0046977; F:TAP binding; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C05_HUMAN              Reviewed;         366 AA.
AC   Q9TNN7; O02866; O62888; Q9TPV8; Q9TPX2;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-5 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*5;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C06_HUMAN              Reviewed;         366 AA.
AC   Q29963; O19505; O78063; Q29989;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-6 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*6;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C07_HUMAN              Reviewed;         366 AA.
AC   P10321; O78061; O78083; Q29631; Q29652; Q29867; Q29990; Q95463;
AC   Q95603; Q9MY31; Q9TQP9;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-7 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*7;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C08_HUMAN              Reviewed;         366 AA.
AC   P30505; P30506; P30507;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-8 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*8;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C14_HUMAN              Reviewed;         366 AA.
AC   P30510; O62879; O78178; Q29641; Q30192; Q9MY35; Q9TQJ5;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-14 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*14;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C12_HUMAN              Reviewed;         366 AA.
AC   P30508; O02863; O19652; O62882; O78062; O78166; O78211; O78214;
AC   P30509; Q29768; Q31627; Q860R1; Q860R2; Q99528; Q9GIK4; Q9TPS4;
AC   Q9UM32; Q9UM33;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-12 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*12;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C15_HUMAN              Reviewed;         366 AA.
AC   Q07000; O78165; Q29864; Q29991; Q31605; Q9BD28; Q9GJ33; Q9MY49;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-15 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*15;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C17_HUMAN              Reviewed;         372 AA.
AC   Q95604; O02864; O02958; Q29643; Q9MY30;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-17 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*17;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=D6S204, HLA-JY3, HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C18_HUMAN              Reviewed;         366 AA.
AC   Q29865; O78203; P79498;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-18 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*18;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   1C16_HUMAN              Reviewed;         366 AA.
AC   Q29960; O78091; O78202; Q29862; Q29959; Q9MY74; Q9MYI3; Q9TNZ8;
DE   RecName: Full=HLA class I histocompatibility antigen, Cw-16 alpha chain;
DE   AltName: Full=MHC class I antigen Cw*16;
DE   Flags: Precursor;
GN   Name=HLA-C; Synonyms=HLAC;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   2A5A_HUMAN              Reviewed;         486 AA.
AC   Q15172; B2R6D2; B7Z7L2; D3DT99; Q2NL72; Q5VVB2; Q8TBI9;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform;
DE   AltName: Full=PP2A B subunit isoform B'-alpha;
DE   AltName: Full=PP2A B subunit isoform B56-alpha;
DE   AltName: Full=PP2A B subunit isoform PR61-alpha;
DE            Short=PR61alpha;
DE   AltName: Full=PP2A B subunit isoform R5-alpha;
GN   Name=PPP2R5A;
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0090219; P:negative regulation of lipid kinase activity; IMP:BHF-UCL.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   2A5B_HUMAN              Reviewed;         497 AA.
AC   Q15173; Q13853;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform;
DE   AltName: Full=PP2A B subunit isoform B'-beta;
DE   AltName: Full=PP2A B subunit isoform B56-beta;
DE   AltName: Full=PP2A B subunit isoform PR61-beta;
DE   AltName: Full=PP2A B subunit isoform R5-beta;
GN   Name=PPP2R5B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
//
ID   2A5D_HUMAN              Reviewed;         602 AA.
AC   Q14738; A8K3I9; B5BUA6; O00494; O00696; Q15171; Q5TC39;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform;
DE   AltName: Full=PP2A B subunit isoform B'-delta;
DE   AltName: Full=PP2A B subunit isoform B56-delta;
DE   AltName: Full=PP2A B subunit isoform PR61-delta;
DE   AltName: Full=PP2A B subunit isoform R5-delta;
GN   Name=PPP2R5D;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   2A5E_HUMAN              Reviewed;         467 AA.
AC   Q16537; A4FU37; B7ZKK8; B7ZKK9; Q52LW4;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform;
DE   AltName: Full=PP2A B subunit isoform B'-epsilon;
DE   AltName: Full=PP2A B subunit isoform B56-epsilon;
DE   AltName: Full=PP2A B subunit isoform PR61-epsilon;
DE   AltName: Full=PP2A B subunit isoform R5-epsilon;
GN   Name=PPP2R5E;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   2A5G_HUMAN              Reviewed;         524 AA.
AC   Q13362; B4DYJ8; B5BUA5; F5GWP3; Q14391; Q15060; Q15174; Q6ZN33;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform;
DE   AltName: Full=PP2A B subunit isoform B'-gamma;
DE   AltName: Full=PP2A B subunit isoform B56-gamma;
DE   AltName: Full=PP2A B subunit isoform PR61-gamma;
DE   AltName: Full=PP2A B subunit isoform R5-gamma;
DE   AltName: Full=Renal carcinoma antigen NY-REN-29;
GN   Name=PPP2R5C; Synonyms=KIAA0044;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; IDA:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:MGI.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   2AAA_HUMAN              Reviewed;         589 AA.
AC   P30153; Q13773; Q6ICQ3; Q96DH3;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform;
DE   AltName: Full=Medium tumor antigen-associated 61 kDa protein;
DE   AltName: Full=PP2A subunit A isoform PR65-alpha;
DE   AltName: Full=PP2A subunit A isoform R1-alpha;
GN   Name=PPP2R1A;
DR   GO; GO:0003823; F:antigen binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; NAS:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IDA:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; NAS:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0070262; P:peptidyl-serine dephosphorylation; IEA:Ensembl.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; NAS:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; NAS:UniProtKB.
DR   GO; GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB.
//
ID   2AAB_HUMAN              Reviewed;         601 AA.
AC   P30154; A8MY67; B0YJ69; B4DGQ6; B4DK91; B4DWW5; F8W8G1; O75620;
AC   Q8NHV8;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform;
DE   AltName: Full=PP2A subunit A isoform PR65-beta;
DE   AltName: Full=PP2A subunit A isoform R1-beta;
GN   Name=PPP2R1B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IMP:UniProtKB.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
//
ID   2ABA_HUMAN              Reviewed;         447 AA.
AC   P63151; B2RBU8; B4E1T7; P50409; Q00007;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform;
DE   AltName: Full=PP2A subunit B isoform B55-alpha;
DE   AltName: Full=PP2A subunit B isoform PR55-alpha;
DE   AltName: Full=PP2A subunit B isoform R2-alpha;
DE   AltName: Full=PP2A subunit B isoform alpha;
GN   Name=PPP2R2A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   2ABB_HUMAN              Reviewed;         443 AA.
AC   Q00005; A6NEJ2; A8K102; B3KPD0; B7Z2F2; B7Z304; D3DQF7; D3DQF8;
AC   G3V149;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform;
DE   AltName: Full=PP2A subunit B isoform B55-beta;
DE   AltName: Full=PP2A subunit B isoform PR55-beta;
DE   AltName: Full=PP2A subunit B isoform R2-beta;
DE   AltName: Full=PP2A subunit B isoform beta;
GN   Name=PPP2R2B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   2ABD_HUMAN              Reviewed;         453 AA.
AC   Q66LE6; A8KAK0; Q5SQJ2; Q9P1Y7;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform;
DE   AltName: Full=PP2A subunit B isoform B55-delta;
DE   AltName: Full=PP2A subunit B isoform PR55-delta;
DE   AltName: Full=PP2A subunit B isoform R2-delta;
DE   AltName: Full=PP2A subunit B isoform delta;
GN   Name=PPP2R2D; Synonyms=KIAA1541;
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
DR   GO; GO:0010458; P:exit from mitosis; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   2ABG_HUMAN              Reviewed;         447 AA.
AC   Q9Y2T4; A8MSY7; B7Z3Y1; Q7Z4V7; Q8NEC4; Q9H3G7;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform;
DE   AltName: Full=IMYPNO1;
DE   AltName: Full=PP2A subunit B isoform B55-gamma;
DE   AltName: Full=PP2A subunit B isoform PR55-gamma;
DE   AltName: Full=PP2A subunit B isoform R2-gamma;
DE   AltName: Full=PP2A subunit B isoform gamma;
GN   Name=PPP2R2C;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; NAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   2B11_HUMAN              Reviewed;         266 AA.
AC   P04229; A4F5N0; A8K098; O62869; P13758; Q06662; Q30116; Q30117;
AC   Q5Y7E9; Q7M2H4; Q95461; Q9BCL7; Q9GIK5; Q9MXZ0; Q9MXZ5; Q9TQ91;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-1 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*1;
DE            Short=DR-1;
DE            Short=DR1;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016045; P:detection of bacterium; ISS:UniProtKB.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; ISS:UniProtKB.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; ISS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; ISS:UniProtKB.
DR   GO; GO:2001179; P:regulation of interleukin-10 secretion; ISS:UniProtKB.
DR   GO; GO:0032673; P:regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042088; P:T-helper 1 type immune response; ISS:UniProtKB.
//
ID   2B13_HUMAN              Reviewed;         266 AA.
AC   P01912;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-3 chain;
DE   AltName: Full=Clone P2-beta-3;
DE   AltName: Full=MHC class II antigen DRB1*3;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IDA:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; IDA:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B14_HUMAN              Reviewed;         266 AA.
AC   P13760; O19717; O19739; P13759; Q29875; Q30145; Q9GIX9; Q9GIY4;
AC   Q9MY13; Q9XRY5;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-4 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*4;
DE            Short=DR-4;
DE            Short=DR4;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0032395; F:MHC class II receptor activity; TAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016045; P:detection of bacterium; ISS:UniProtKB.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; ISS:UniProtKB.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IDA:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IDA:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; ISS:UniProtKB.
DR   GO; GO:2001179; P:regulation of interleukin-10 secretion; ISS:UniProtKB.
DR   GO; GO:0032673; P:regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042088; P:T-helper 1 type immune response; ISS:UniProtKB.
//
ID   2B17_HUMAN              Reviewed;         266 AA.
AC   P13761; B0UYW1; O46699; O46872;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-7 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*7;
DE            Short=DR-7;
DE            Short=DR7;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0032395; F:MHC class II receptor activity; TAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016045; P:detection of bacterium; IMP:UniProtKB.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; IDA:UniProtKB.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IDA:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IMP:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IMP:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:2001179; P:regulation of interleukin-10 secretion; IDA:UniProtKB.
DR   GO; GO:0032673; P:regulation of interleukin-4 production; IDA:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042088; P:T-helper 1 type immune response; IMP:UniProtKB.
//
ID   2B18_HUMAN              Reviewed;         266 AA.
AC   Q30134; O19718; O19788; Q29968; Q30108; Q30115; Q9BCP0; Q9BCP1;
AC   Q9BCP2; Q9BD33; Q9TQ37; Q9UIM9;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-8 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*8;
DE            Short=DR-8;
DE            Short=DR8;
DE            Short=DRw8;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B1A_HUMAN              Reviewed;         266 AA.
AC   Q30167; P01914; Q9MYF5;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-10 beta chain;
DE   AltName: Full=DRw10;
DE   AltName: Full=MHC class II antigen DRB1*10;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B19_HUMAN              Reviewed;         266 AA.
AC   Q9TQE0; Q30149;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-9 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*9;
DE            Short=DR-9;
DE            Short=DR9;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016045; P:detection of bacterium; ISS:UniProtKB.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; ISS:UniProtKB.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; ISS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; ISS:UniProtKB.
DR   GO; GO:2001179; P:regulation of interleukin-10 secretion; ISS:UniProtKB.
DR   GO; GO:0032673; P:regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042088; P:T-helper 1 type immune response; ISS:UniProtKB.
//
ID   2B1B_HUMAN              Reviewed;         266 AA.
AC   P20039; Q30006; Q9GIX8;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-11 beta chain;
DE   AltName: Full=DR-5;
DE            Short=DR5;
DE   AltName: Full=DRw11;
DE   AltName: Full=MHC class II antigen DRB1*11;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0032395; F:MHC class II receptor activity; TAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B1D_HUMAN              Reviewed;         266 AA.
AC   Q5Y7A7; A0MWF2; A2ICT1; A4ZXA5; A4ZXA6; A7UHG2; A7X5K7; A8YQE9;
AC   B0BK85; B3VTQ3; B5A8Y2; B5A8Y3; B5B9V6; B5QSK8; C0LAB5; O02930;
AC   O62889; O78047; P79545; Q14280; Q14QT2; Q19K86; Q1G0Z9; Q1KLJ6;
AC   Q29673; Q29720; Q29722; Q29806; Q29833; Q29874; Q29886; Q2MF40;
AC   Q2YHQ2; Q30112; Q3LA93; Q3LA94; Q3LA95; Q3LA96; Q3LA97; Q3LA98;
AC   Q3LA99; Q3LAA0; Q3LAA1; Q3LAA2; Q3MQ60; Q53IG1; Q56FP2; Q56FP3;
AC   Q58F52; Q5K3W2; Q5UBA2; Q5W3L4; Q6REE2; Q6U387; Q701T1; Q70Q85;
AC   Q768U2; Q7YP03; Q7YQ26; Q7YQA3; Q860E5; Q860H8; Q860Z3; Q861G6;
AC   Q861H0; Q861H4; Q8HWQ6; Q8WMA0; Q95389; Q95HL1; Q96HZ9; Q9BCP5;
AC   Q9BD21; Q9GIP3; Q9GJ25; Q9GJ60; Q9GJF8; Q9GJF9; Q9GJG0; Q9MY45;
AC   Q9MY56; Q9TPW3; Q9TPW9; Q9TPX4; Q9UBY1; Q9UIN0; Q9XRX1; Q9Y453;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-13 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*13;
DE            Short=DR-13;
DE            Short=DR13;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B1C_HUMAN              Reviewed;         266 AA.
AC   Q95IE3; A7LA26; B0LUZ6; B6VCX2; B7UDB2; O19585; Q19AF2; Q29771;
AC   Q2L9H4; Q2MZ92; Q5EER6; Q5NDB9; Q5UT58; Q5Y7G0; Q768U4; Q7YP04;
AC   Q861H8; Q95IT6; Q9BD40;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-12 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*12;
DE            Short=DR-12;
DE            Short=DR12;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B1E_HUMAN              Reviewed;         266 AA.
AC   Q9GIY3; A0N0W1; A2TGX3; A4ZY86; A5H000; A5HKN8; A7DZP9; A7X5B1;
AC   A7X5B7; A7X5E0; A7X5E6; A7X5H8; A9JPG0; B1GWE7; B2CR03; B2LVF9;
AC   B2NJ29; B2ZCY1; B3VTP8; B5B8U0; B5B9V5; B5LZ25; B6VEL9; B9VRA4;
AC   B9X248; O02876; O46793; O77969; O78210; Q0PQ39; Q155F7; Q1AP33;
AC   Q1JRP3; Q27PR6; Q27PR7; Q29734; Q29770; Q29772; Q29800; Q2A120;
AC   Q2HZE5; Q2LE76; Q2MJA6; Q2VQU1; Q307W5; Q31636; Q3LA87; Q3LA88;
AC   Q3LA89; Q3LA90; Q3LA91; Q3LA92; Q3T919; Q4PRC3; Q4PRC5; Q4VZY7;
AC   Q56FP1; Q5BM92; Q5U9W6; Q683P7; Q70GL2; Q7YNY9; Q7YQA5; Q860D8;
AC   Q860D9; Q860S0; Q861H5; Q861H7; Q8MH59; Q8MH60; Q8WLU3; Q95348;
AC   Q95HK1; Q95HL0; Q95IG2; Q9GIL5; Q9GIL6; Q9GIY0; Q9GIY1; Q9GIY2;
AC   Q9GJ56; Q9GJ57; Q9GJ58; Q9TPB6; Q9TPW1; Q9XRY4; Q9Y4H7;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-14 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*14;
DE            Short=DR-14;
DE            Short=DR14;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B1F_HUMAN              Reviewed;         266 AA.
AC   P01911; Q29790; Q29975; Q30142; Q30166; Q32MY7; Q56FN9; Q5Y7B0;
AC   Q5Y7B9;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-15 beta chain;
DE   AltName: Full=DW2.2/DR2.2;
DE   AltName: Full=MHC class II antigen DRB1*15;
DE   Flags: Precursor;
GN   Name=HLA-DRB1; Synonyms=HLA-DRB2;
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   2B1G_HUMAN              Reviewed;         266 AA.
AC   Q29974; A7X5J4; O98212; Q0PGR5; Q29792; Q30120; Q30159; Q30200;
AC   Q3HUP9; Q3KTM1; Q3LA84; Q6T865; Q95383;
DE   RecName: Full=HLA class II histocompatibility antigen, DRB1-16 beta chain;
DE   AltName: Full=MHC class II antigen DRB1*16;
DE            Short=DR-16;
DE            Short=DR16;
DE   Flags: Precursor;
GN   Name=HLA-DRB1;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016045; P:detection of bacterium; ISS:UniProtKB.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; ISS:UniProtKB.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; ISS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; ISS:UniProtKB.
DR   GO; GO:2001179; P:regulation of interleukin-10 secretion; ISS:UniProtKB.
DR   GO; GO:0032673; P:regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042088; P:T-helper 1 type immune response; ISS:UniProtKB.
//
ID   3BHS1_HUMAN             Reviewed;         373 AA.
AC   P14060; A8K691; Q14545; Q8IV65;
DE   RecName: Full=3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1;
DE   AltName: Full=3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I;
DE            Short=3-beta-HSD I;
DE   AltName: Full=Trophoblast antigen FDO161G;
DE   Includes:
DE     RecName: Full=3-beta-hydroxy-Delta(5)-steroid dehydrogenase;
DE              EC=1.1.1.145;
DE     AltName: Full=3-beta-hydroxy-5-ene steroid dehydrogenase;
DE     AltName: Full=Progesterone reductase;
DE   Includes:
DE     RecName: Full=Steroid Delta-isomerase;
DE              EC=5.3.3.1;
DE     AltName: Full=Delta-5-3-ketosteroid isomerase;
GN   Name=HSD3B1; Synonyms=3BH, HSDB3A;
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; ISS:UniProtKB.
DR   GO; GO:0004769; F:steroid delta-isomerase activity; ISS:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006703; P:estrogen biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   3BHS2_HUMAN             Reviewed;         372 AA.
AC   P26439; A2RRA5; Q16010; Q53GD4; Q6AI10; Q6LDB9; Q99890; Q9UD08;
DE   RecName: Full=3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2;
DE   AltName: Full=3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II;
DE            Short=3-beta-HSD II;
DE   AltName: Full=3-beta-HSD adrenal and gonadal type;
DE   Includes:
DE     RecName: Full=3-beta-hydroxy-Delta(5)-steroid dehydrogenase;
DE              EC=1.1.1.145;
DE     AltName: Full=3-beta-hydroxy-5-ene steroid dehydrogenase;
DE     AltName: Full=Progesterone reductase;
DE   Includes:
DE     RecName: Full=Steroid Delta-isomerase;
DE              EC=5.3.3.1;
DE     AltName: Full=Delta-5-3-ketosteroid isomerase;
GN   Name=HSD3B2; Synonyms=HSDB3B;
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0004769; F:steroid delta-isomerase activity; IDA:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:Reactome.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   3BHS7_HUMAN             Reviewed;         369 AA.
AC   Q9H2F3; Q96M28; Q9BSN9;
DE   RecName: Full=3 beta-hydroxysteroid dehydrogenase type 7;
DE   AltName: Full=3 beta-hydroxysteroid dehydrogenase type VII;
DE            Short=3-beta-HSD VII;
DE   AltName: Full=3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase;
DE            Short=C(27) 3-beta-HSD;
DE            EC=1.1.1.-;
DE   AltName: Full=Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase;
DE            EC=1.1.1.181;
GN   Name=HSD3B7;
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; NAS:UniProtKB.
DR   GO; GO:0047016; F:cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   3BP1_HUMAN              Reviewed;         701 AA.
AC   Q9Y3L3; Q5R3N0; Q6IBZ2; Q6ZVL9; Q96HQ5; Q9NSQ9;
DE   RecName: Full=SH3 domain-binding protein 1;
DE            Short=3BP-1;
GN   Name=SH3BP1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   3BP2_HUMAN              Reviewed;         561 AA.
AC   P78314; A6NNC2; B2R5R6; B4DT04; D3DVR0; O00500; O15373; P78315;
DE   RecName: Full=SH3 domain-binding protein 2;
DE            Short=3BP-2;
GN   Name=SH3BP2; Synonyms=3BP2; ORFNames=RES4-23;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   3BP5L_HUMAN             Reviewed;         393 AA.
AC   Q7L8J4; Q96FI5; Q9BQH8; Q9C0E3;
DE   RecName: Full=SH3 domain-binding protein 5-like;
DE            Short=SH3BP-5-like;
GN   Name=SH3BP5L; Synonyms=KIAA1720; ORFNames=UNQ2766/PRO7133;
//
ID   3BP5_HUMAN              Reviewed;         455 AA.
AC   O60239; B3KQW6; Q5JWV9;
DE   RecName: Full=SH3 domain-binding protein 5;
DE            Short=SH3BP-5;
DE   AltName: Full=SH3 domain-binding protein that preferentially associates with BTK;
GN   Name=SH3BP5; Synonyms=SAB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IDA:MGI.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   3HAO_HUMAN              Reviewed;         286 AA.
AC   P46952; A6NE56; B4DIN2; Q53QZ7; Q8N6N9;
DE   RecName: Full=3-hydroxyanthranilate 3,4-dioxygenase;
DE            EC=1.13.11.6;
DE   AltName: Full=3-hydroxyanthranilate oxygenase;
DE            Short=3-HAO;
DE   AltName: Full=3-hydroxyanthranilic acid dioxygenase;
DE            Short=HAD;
GN   Name=HAAO;
DR   GO; GO:0000334; F:3-hydroxyanthranilate 3,4-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0019825; F:oxygen binding; IEA:Ensembl.
DR   GO; GO:0034354; P:'de novo' NAD biosynthetic process from tryptophan; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043420; P:anthranilate metabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0070050; P:neuron cellular homeostasis; IMP:UniProtKB.
DR   GO; GO:0019805; P:quinolinate biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0046686; P:response to cadmium ion; IDA:UniProtKB.
DR   GO; GO:0010043; P:response to zinc ion; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
//
ID   3HIDH_HUMAN             Reviewed;         336 AA.
AC   P31937; Q546Z2; Q9UDN3;
DE   RecName: Full=3-hydroxyisobutyrate dehydrogenase, mitochondrial;
DE            Short=HIBADH;
DE            EC=1.1.1.31;
DE   Flags: Precursor;
GN   Name=HIBADH;
DR   GO; GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006574; P:valine catabolic process; IDA:UniProtKB.
//
ID   3MG_HUMAN               Reviewed;         298 AA.
AC   P29372; G5E9E2; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33;
AC   Q9NNX5;
DE   RecName: Full=DNA-3-methyladenine glycosylase;
DE            EC=3.2.2.21;
DE   AltName: Full=3-alkyladenine DNA glycosylase;
DE   AltName: Full=3-methyladenine DNA glycosidase;
DE   AltName: Full=ADPG;
DE   AltName: Full=N-methylpurine-DNA glycosylase;
DE   Flags: Precursor;
GN   Name=MPG; Synonyms=AAG, ANPG, MID1;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0008725; F:DNA-3-methyladenine glycosylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052822; F:DNA-3-methylguanine glycosylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052821; F:DNA-7-methyladenine glycosylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043916; F:DNA-7-methylguanine glycosylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0045007; P:depurination; TAS:Reactome.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   41_HUMAN                Reviewed;         864 AA.
AC   P11171; B1ALH8; B1ALH9; D3DPM9; D3DPN0; P11176; Q14245; Q5TB35;
AC   Q5VXN8; Q8IXV9; Q9Y578; Q9Y579;
DE   RecName: Full=Protein 4.1;
DE            Short=P4.1;
DE   AltName: Full=4.1R;
DE   AltName: Full=Band 4.1;
DE   AltName: Full=EPB4.1;
GN   Name=EPB41; Synonyms=E41P;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; TAS:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
//
ID   4EBP1_HUMAN             Reviewed;         118 AA.
AC   Q13541; B2R502; D3DSW8; Q6IBN3;
DE   RecName: Full=Eukaryotic translation initiation factor 4E-binding protein 1;
DE            Short=4E-BP1;
DE            Short=eIF4E-binding protein 1;
DE   AltName: Full=Phosphorylated heat- and acid-stable protein regulated by insulin 1;
DE            Short=PHAS-I;
GN   Name=EIF4EBP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030371; F:translation repressor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IEA:Ensembl.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0031929; P:TOR signaling; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   4EBP2_HUMAN             Reviewed;         120 AA.
AC   Q13542;
DE   RecName: Full=Eukaryotic translation initiation factor 4E-binding protein 2;
DE            Short=4E-BP2;
DE            Short=eIF4E-binding protein 2;
GN   Name=EIF4EBP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IEA:InterPro.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   4EBP3_HUMAN             Reviewed;         100 AA.
AC   O60516;
DE   RecName: Full=Eukaryotic translation initiation factor 4E-binding protein 3;
DE            Short=4E-BP3;
DE            Short=eIF4E-binding protein 3;
GN   Name=EIF4EBP3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030371; F:translation repressor activity; NAS:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; NAS:UniProtKB.
//
ID   4ET_HUMAN               Reviewed;         985 AA.
AC   Q9NRA8; B1AKL2; B1AKL3; B2RBF1; Q8NCF2; Q9H708;
DE   RecName: Full=Eukaryotic translation initiation factor 4E transporter;
DE            Short=4E-T;
DE            Short=eIF4E transporter;
DE   AltName: Full=Eukaryotic translation initiation factor 4E nuclear import factor 1;
GN   Name=EIF4ENIF1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; TAS:ProtInc.
//
ID   4F2_HUMAN               Reviewed;         630 AA.
AC   P08195; Q13543;
DE   RecName: Full=4F2 cell-surface antigen heavy chain;
DE            Short=4F2hc;
DE   AltName: Full=4F2 heavy chain antigen;
DE   AltName: Full=Lymphocyte activation antigen 4F2 large subunit;
DE   AltName: Full=Solute carrier family 3 member 2;
DE   AltName: CD_antigen=CD98;
GN   Name=SLC3A2; Synonyms=MDU1;
DR   GO; GO:0005432; F:calcium:sodium antiporter activity; TAS:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006865; P:amino acid transport; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0060356; P:leucine import; ISS:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IMP:MGI.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015827; P:tryptophan transport; ISS:UniProtKB.
//
ID   5HT1A_HUMAN             Reviewed;         422 AA.
AC   P08908; Q6LAE7;
DE   RecName: Full=5-hydroxytryptamine receptor 1A;
DE            Short=5-HT-1A;
DE            Short=5-HT1A;
DE   AltName: Full=G-21;
DE   AltName: Full=Serotonin receptor 1A;
GN   Name=HTR1A; Synonyms=ADRB2RL1, ADRBRL1;
DR   GuidetoPHARMACOLOGY; 1; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0007198; P:adenylate cyclase-inhibiting serotonin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:InterPro.
DR   GO; GO:0035640; P:exploration behavior; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0050795; P:regulation of behavior; IEA:InterPro.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0046883; P:regulation of hormone secretion; IEA:InterPro.
DR   GO; GO:0014062; P:regulation of serotonin secretion; ISS:UniProtKB.
DR   GO; GO:0042428; P:serotonin metabolic process; ISS:UniProtKB.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042310; P:vasoconstriction; IEA:InterPro.
//
ID   5HT1B_HUMAN             Reviewed;         390 AA.
AC   P28222; Q4VAY7;
DE   RecName: Full=5-hydroxytryptamine receptor 1B;
DE            Short=5-HT-1B;
DE            Short=5-HT1B;
DE   AltName: Full=S12;
DE   AltName: Full=Serotonin 1D beta receptor;
DE            Short=5-HT-1D-beta;
DE   AltName: Full=Serotonin receptor 1B;
GN   Name=HTR1B; Synonyms=HTR1DB;
DR   GuidetoPHARMACOLOGY; 2; -.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0051378; F:serotonin binding; IEA:Ensembl.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0007198; P:adenylate cyclase-inhibiting serotonin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0071312; P:cellular response to alkaloid; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0071502; P:cellular response to temperature stimulus; IEA:Ensembl.
DR   GO; GO:0042756; P:drinking behavior; IEA:Ensembl.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0014063; P:negative regulation of serotonin secretion; ISS:UniProtKB.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050795; P:regulation of behavior; IEA:InterPro.
DR   GO; GO:0014059; P:regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051385; P:response to mineralocorticoid; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0042310; P:vasoconstriction; IEA:InterPro.
//
ID   5HT1D_HUMAN             Reviewed;         377 AA.
AC   P28221;
DE   RecName: Full=5-hydroxytryptamine receptor 1D;
DE            Short=5-HT-1D;
DE            Short=5-HT1D;
DE   AltName: Full=Serotonin 1D alpha receptor;
DE            Short=5-HT-1D-alpha;
DE   AltName: Full=Serotonin receptor 1D;
GN   Name=HTR1D; Synonyms=HTR1DA, HTRL;
DR   GuidetoPHARMACOLOGY; 3; -.
DR   GO; GO:0051378; F:serotonin binding; IEA:Ensembl.
DR   GO; GO:0004993; F:serotonin receptor activity; IMP:UniProtKB.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0014827; P:intestine smooth muscle contraction; IMP:UniProtKB.
DR   GO; GO:0050795; P:regulation of behavior; IEA:InterPro.
DR   GO; GO:0040012; P:regulation of locomotion; IEA:InterPro.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0042310; P:vasoconstriction; IEA:InterPro.
//
ID   5HT1E_HUMAN             Reviewed;         365 AA.
AC   P28566; E1P503; Q9P1Y1;
DE   RecName: Full=5-hydroxytryptamine receptor 1E;
DE            Short=5-HT-1E;
DE            Short=5-HT1E;
DE   AltName: Full=S31;
DE   AltName: Full=Serotonin receptor 1E;
GN   Name=HTR1E;
DR   GuidetoPHARMACOLOGY; 4; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0051378; F:serotonin binding; IDA:MGI.
DR   GO; GO:0004993; F:serotonin receptor activity; IMP:UniProtKB.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0030815; P:negative regulation of cAMP metabolic process; IEA:InterPro.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   5HT1F_HUMAN             Reviewed;         366 AA.
AC   P30939;
DE   RecName: Full=5-hydroxytryptamine receptor 1F;
DE            Short=5-HT-1F;
DE            Short=5-HT1F;
DE   AltName: Full=Serotonin receptor 1F;
GN   Name=HTR1F; Synonyms=HTR1EL;
DR   GuidetoPHARMACOLOGY; 5; -.
DR   GO; GO:0051378; F:serotonin binding; IDA:MGI.
DR   GO; GO:0004993; F:serotonin receptor activity; IMP:UniProtKB.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   5HT2A_HUMAN             Reviewed;         471 AA.
AC   P28223; B2RAC5; B4DZ79; F5GWE8; Q5T8C0;
DE   RecName: Full=5-hydroxytryptamine receptor 2A;
DE            Short=5-HT-2;
DE            Short=5-HT-2A;
DE   AltName: Full=Serotonin receptor 2A;
GN   Name=HTR2A; Synonyms=HTR2;
DR   GuidetoPHARMACOLOGY; 6; -.
DR   GO; GO:0071886; F:1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0051378; F:serotonin binding; IDA:UniProtKB.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0007208; P:phospholipase C-activating serotonin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0050795; P:regulation of behavior; IEA:InterPro.
DR   GO; GO:0014059; P:regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0046883; P:regulation of hormone secretion; IEA:InterPro.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
DR   GO; GO:0014832; P:urinary bladder smooth muscle contraction; IEA:Ensembl.
//
ID   5HT2B_HUMAN             Reviewed;         481 AA.
AC   P41595; B2R9D5; Q53TI1; Q62221; Q6P523;
DE   RecName: Full=5-hydroxytryptamine receptor 2B;
DE            Short=5-HT-2B;
DE            Short=5-HT2B;
DE   AltName: Full=Serotonin receptor 2B;
GN   Name=HTR2B;
DR   GuidetoPHARMACOLOGY; 7; -.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; IMP:UniProtKB.
DR   GO; GO:0005099; F:Ras GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0051378; F:serotonin binding; IDA:UniProtKB.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0007610; P:behavior; IEA:UniProtKB-KW.
DR   GO; GO:0019722; P:calcium-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0003300; P:cardiac muscle hypertrophy; ISS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0071502; P:cellular response to temperature stimulus; ISS:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0048598; P:embryonic morphogenesis; ISS:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:UniProtKB.
DR   GO; GO:0014827; P:intestine smooth muscle contraction; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.
DR   GO; GO:0014033; P:neural crest cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; IMP:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0070528; P:protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0050795; P:regulation of behavior; IMP:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0042310; P:vasoconstriction; IMP:UniProtKB.
//
ID   5HT2C_HUMAN             Reviewed;         458 AA.
AC   P28335; B1AMW4; Q5VUF8; Q9NP28;
DE   RecName: Full=5-hydroxytryptamine receptor 2C;
DE            Short=5-HT-2C;
DE            Short=5-HT2C;
DE            Short=5-HTR2C;
DE   AltName: Full=5-hydroxytryptamine receptor 1C;
DE            Short=5-HT-1C;
DE            Short=5-HT1C;
DE   AltName: Full=Serotonin receptor 2C;
DE   Flags: Precursor;
GN   Name=HTR2C; Synonyms=HTR1C;
DR   GuidetoPHARMACOLOGY; 8; -.
DR   GO; GO:0071886; F:1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0001587; F:Gq/11-coupled serotonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0051378; F:serotonin binding; IDA:UniProtKB.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:MGI.
DR   GO; GO:0001662; P:behavioral fear response; ISS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007631; P:feeding behavior; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:InterPro.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007208; P:phospholipase C-activating serotonin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; ISS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032098; P:regulation of appetite; ISS:UniProtKB.
DR   GO; GO:0043397; P:regulation of corticotropin-releasing hormone secretion; ISS:UniProtKB.
DR   GO; GO:0031644; P:regulation of neurological system process; ISS:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   5HT3A_HUMAN             Reviewed;         478 AA.
AC   P46098; B4DSY6; G5E986; O60854; Q7KZM7; Q99918; Q9BSZ9;
DE   RecName: Full=5-hydroxytryptamine receptor 3A;
DE            Short=5-HT3-A;
DE            Short=5-HT3A;
DE   AltName: Full=5-hydroxytryptamine receptor 3;
DE            Short=5-HT-3;
DE            Short=5-HT3R;
DE   AltName: Full=Serotonin receptor 3A;
DE   AltName: Full=Serotonin-gated ion channel receptor;
DE   Flags: Precursor;
GN   Name=HTR3A; Synonyms=5HT3R, HTR3;
DR   GuidetoPHARMACOLOGY; 373; -.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0051378; F:serotonin binding; IDA:MGI.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:MGI.
DR   GO; GO:0005232; F:serotonin-activated cation-selective channel activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   5HT3B_HUMAN             Reviewed;         441 AA.
AC   O95264; B0YJ23; Q0VJC3;
DE   RecName: Full=5-hydroxytryptamine receptor 3B;
DE            Short=5-HT3-B;
DE            Short=5-HT3B;
DE   AltName: Full=Serotonin receptor 3B;
DE   Flags: Precursor;
GN   Name=HTR3B;
DR   GuidetoPHARMACOLOGY; 374; -.
DR   GO; GO:0005216; F:ion channel activity; TAS:ProtInc.
DR   GO; GO:0004993; F:serotonin receptor activity; TAS:ProtInc.
DR   GO; GO:0005232; F:serotonin-activated cation-selective channel activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   5HT3C_HUMAN             Reviewed;         447 AA.
AC   Q8WXA8; A2RRR5;
DE   RecName: Full=5-hydroxytryptamine receptor 3C;
DE            Short=5-HT3-C;
DE            Short=5-HT3C;
DE   AltName: Full=Serotonin receptor 3C;
DE   Flags: Precursor;
GN   Name=HTR3C;
DR   GuidetoPHARMACOLOGY; 375; -.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   5HT3D_HUMAN             Reviewed;         454 AA.
AC   Q70Z44; C9J2I6; J3QT78; Q495N5; Q495N6; Q7Z6B3;
DE   RecName: Full=5-hydroxytryptamine receptor 3D;
DE            Short=5-HT3-D;
DE            Short=5-HT3D;
DE   AltName: Full=Serotonin receptor 3D;
DE   Flags: Precursor;
GN   Name=HTR3D;
DR   GuidetoPHARMACOLOGY; 376; -.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   5HT3E_HUMAN             Reviewed;         456 AA.
AC   A5X5Y0; A8IKD7; E9PGF1; Q495G1; Q495G3; Q6V706; Q6V707; Q7Z6B2;
DE   RecName: Full=5-hydroxytryptamine receptor 3E;
DE            Short=5-HT3-E;
DE            Short=5-HT3E;
DE   AltName: Full=Serotonin receptor 3E;
DE   Flags: Precursor;
GN   Name=HTR3E;
DR   GuidetoPHARMACOLOGY; 377; -.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   5HT4R_HUMAN             Reviewed;         388 AA.
AC   Q13639; C4WYH4; Q546Q1; Q684M0; Q712M9; Q96KH9; Q96KI0; Q9H199;
AC   Q9NY73; Q9UBM6; Q9UBT4; Q9UE22; Q9UE23; Q9UQR6;
DE   RecName: Full=5-hydroxytryptamine receptor 4;
DE            Short=5-HT-4;
DE            Short=5-HT4;
DE   AltName: Full=Serotonin receptor 4;
GN   Name=HTR4;
DR   GuidetoPHARMACOLOGY; 9; -.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:MGI.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0032098; P:regulation of appetite; IEA:InterPro.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; IEA:InterPro.
//
ID   5HT5A_HUMAN             Reviewed;         357 AA.
AC   P47898; Q2M2D2;
DE   RecName: Full=5-hydroxytryptamine receptor 5A;
DE            Short=5-HT-5;
DE            Short=5-HT-5A;
DE            Short=5-HT5A;
DE   AltName: Full=Serotonin receptor 5A;
GN   Name=HTR5A;
DR   GuidetoPHARMACOLOGY; 10; -.
DR   GO; GO:0004993; F:serotonin receptor activity; IDA:MGI.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; IDA:GOC.
//
ID   5HT6R_HUMAN             Reviewed;         440 AA.
AC   P50406; Q13640; Q5TGZ1;
DE   RecName: Full=5-hydroxytryptamine receptor 6;
DE            Short=5-HT-6;
DE            Short=5-HT6;
DE   AltName: Full=Serotonin receptor 6;
GN   Name=HTR6;
DR   GuidetoPHARMACOLOGY; 11; -.
DR   GO; GO:0004969; F:histamine receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004993; F:serotonin receptor activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0014058; P:negative regulation of acetylcholine secretion, neurotransmission; IEA:Ensembl.
DR   GO; GO:0014053; P:negative regulation of gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0033603; P:positive regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0014054; P:positive regulation of gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   5HT7R_HUMAN             Reviewed;         479 AA.
AC   P34969; B5BUP6; P78336; P78372; P78516; Q5VX01; Q5VX02; Q5VX03;
DE   RecName: Full=5-hydroxytryptamine receptor 7;
DE            Short=5-HT-7;
DE            Short=5-HT7;
DE   AltName: Full=5-HT-X;
DE   AltName: Full=Serotonin receptor 7;
GN   Name=HTR7;
DR   GuidetoPHARMACOLOGY; 12; -.
DR   GO; GO:0004993; F:serotonin receptor activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007210; P:serotonin receptor signaling pathway; TAS:GOC.
DR   GO; GO:0006939; P:smooth muscle contraction; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0042310; P:vasoconstriction; IEA:InterPro.
//
ID   5NT1B_HUMAN             Reviewed;         610 AA.
AC   Q96P26; B5MCR0; B7ZVX7; Q53RX2; Q8N9W3; Q8NA26; Q96DU5; Q96KE6;
AC   Q96M25; Q96SA3;
DE   RecName: Full=Cytosolic 5'-nucleotidase 1B;
DE            Short=cN1B;
DE            EC=3.1.3.5;
DE   AltName: Full=Autoimmune infertility-related protein;
DE   AltName: Full=Cytosolic 5'-nucleotidase IB;
DE            Short=cN-IB;
GN   Name=NT5C1B; Synonyms=AIRP; ORFNames=FKSG85;
DR   GO; GO:0008253; F:5'-nucleotidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   5NT1A_HUMAN             Reviewed;         368 AA.
AC   Q9BXI3; Q3SYB9; Q5TG98; Q9BWT8;
DE   RecName: Full=Cytosolic 5'-nucleotidase 1A;
DE            Short=cN1A;
DE            EC=3.1.3.5;
DE   AltName: Full=Cytosolic 5'-nucleotidase IA;
DE            Short=cN-I;
DE            Short=cN-IA;
GN   Name=NT5C1A;
DR   GO; GO:0008253; F:5'-nucleotidase activity; NAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0046085; P:adenosine metabolic process; IEA:Ensembl.
DR   GO; GO:0016311; P:dephosphorylation; EXP:GOC.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009116; P:nucleoside metabolic process; NAS:UniProtKB.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009128; P:purine nucleoside monophosphate catabolic process; IEA:Ensembl.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   5NT3A_HUMAN             Reviewed;         336 AA.
AC   Q9H0P0; A8K253; B2RAA5; B8ZZC4; Q6IPZ1; Q6NXS6; Q7L3G6; Q9P0P5;
AC   Q9UC42; Q9UC43; Q9UC44; Q9UC45;
DE   RecName: Full=Cytosolic 5'-nucleotidase 3A;
DE            EC=3.1.3.5;
DE   AltName: Full=Cytosolic 5'-nucleotidase 3;
DE   AltName: Full=Cytosolic 5'-nucleotidase III;
DE            Short=cN-III;
DE   AltName: Full=Pyrimidine 5'-nucleotidase 1;
DE            Short=P5'N-1;
DE            Short=P5N-1;
DE            Short=PN-I;
DE   AltName: Full=Uridine 5'-monophosphate hydrolase 1;
DE   AltName: Full=p36;
GN   Name=NT5C3A; Synonyms=NT5C3, P5N1, UMPH1; ORFNames=HSPC233;
DR   GO; GO:0008665; F:2'-phosphotransferase activity; NAS:UniProtKB.
DR   GO; GO:0008253; F:5'-nucleotidase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0046085; P:adenosine metabolic process; IEA:Ensembl.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0006213; P:pyrimidine nucleoside metabolic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   5NT3B_HUMAN             Reviewed;         300 AA.
AC   Q969T7; A8MWB9; C9JKC4; Q7L3B7;
DE   RecName: Full=7-methylguanosine phosphate-specific 5'-nucleotidase;
DE            Short=7-methylguanosine nucleotidase;
DE            EC=3.1.3.91;
DE   AltName: Full=Cytosolic 5'-nucleotidase 3B;
DE   AltName: Full=Cytosolic 5'-nucleotidase III-like protein;
DE            Short=cN-III-like protein;
DE            EC=3.1.3.5;
DE   AltName: Full=N(7)-methylguanylate 5'-phosphatase;
GN   Name=NT5C3B; Synonyms=NT5C3L;
DR   GO; GO:0008253; F:5'-nucleotidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
//
ID   5NTC_HUMAN              Reviewed;         561 AA.
AC   P49902; B7Z382; D3DR91; Q5JUV5;
DE   RecName: Full=Cytosolic purine 5'-nucleotidase;
DE            EC=3.1.3.5;
DE   AltName: Full=Cytosolic 5'-nucleotidase II;
GN   Name=NT5C2; Synonyms=NT5B, NT5CP, PNT5;
DR   GO; GO:0008253; F:5'-nucleotidase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050146; F:nucleoside phosphotransferase activity; TAS:Reactome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016311; P:dephosphorylation; EXP:GOC.
DR   GO; GO:0017144; P:drug metabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016310; P:phosphorylation; TAS:GOC.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   5NTD_HUMAN              Reviewed;         574 AA.
AC   P21589; B3KQI8; O75520; Q5W116;
DE   RecName: Full=5'-nucleotidase;
DE            Short=5'-NT;
DE            EC=3.1.3.5;
DE   AltName: Full=Ecto-5'-nucleotidase;
DE   AltName: CD_antigen=CD73;
DE   Flags: Precursor;
GN   Name=NT5E; Synonyms=NT5, NTE;
DR   GuidetoPHARMACOLOGY; 1232; -.
DR   GO; GO:0008253; F:5'-nucleotidase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0046086; P:adenosine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006196; P:AMP catabolic process; IEA:Ensembl.
DR   GO; GO:0016311; P:dephosphorylation; EXP:GOC.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   68MP_HUMAN              Reviewed;          58 AA.
AC   P56378; B2R588; G3V5Q3; Q86TT7;
DE   RecName: Full=6.8 kDa mitochondrial proteolipid;
GN   Name=MP68; Synonyms=C14orf2; ORFNames=PRO1574;
//
ID   6PGD_HUMAN              Reviewed;         483 AA.
AC   P52209; A8K2Y9; Q9BWD8;
DE   RecName: Full=6-phosphogluconate dehydrogenase, decarboxylating;
DE            EC=1.1.1.44;
GN   Name=PGD; Synonyms=PGDH;
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0019322; P:pentose biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006098; P:pentose-phosphate shunt; ISS:UniProtKB.
DR   GO; GO:0009051; P:pentose-phosphate shunt, oxidative branch; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   6PGL_HUMAN              Reviewed;         258 AA.
AC   O95336;
DE   RecName: Full=6-phosphogluconolactonase;
DE            Short=6PGL;
DE            EC=3.1.1.31;
GN   Name=PGLS;
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IDA:UniProtKB.
DR   GO; GO:0048029; F:monosaccharide binding; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IDA:UniProtKB.
DR   GO; GO:0009051; P:pentose-phosphate shunt, oxidative branch; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   7B2_HUMAN               Reviewed;         212 AA.
AC   P05408; P01164; Q6FHD0; Q9BS38;
DE   RecName: Full=Neuroendocrine protein 7B2;
DE   AltName: Full=Pituitary polypeptide;
DE   AltName: Full=Secretogranin V;
DE   AltName: Full=Secretogranin-5;
DE   AltName: Full=Secretory granule endocrine protein I;
DE   Contains:
DE     RecName: Full=N-terminal peptide;
DE   Contains:
DE     RecName: Full=C-terminal peptide;
DE   Flags: Precursor;
GN   Name=SCG5; Synonyms=SGNE1;
DR   GO; GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0016486; P:peptide hormone processing; ISS:UniProtKB.
DR   GO; GO:0046883; P:regulation of hormone secretion; ISS:UniProtKB.
//
ID   8ODP_HUMAN              Reviewed;         197 AA.
AC   P36639; A4D205; Q6LES7; Q6P0Y6; Q7Z7N6; Q8IV95; Q9UBM0; Q9UBM9;
DE   RecName: Full=7,8-dihydro-8-oxoguanine triphosphatase;
DE            EC=3.6.1.55;
DE   AltName: Full=2-hydroxy-dATP diphosphatase;
DE            EC=3.6.1.56;
DE   AltName: Full=8-oxo-dGTPase;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 1;
DE            Short=Nudix motif 1;
DE   Flags: Precursor;
GN   Name=NUDT1; Synonyms=MTH1;
DR   GO; GO:0035539; F:8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008413; F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; IDA:UniProtKB.
DR   GO; GO:0047693; F:ATP diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0046061; P:dATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0006203; P:dGTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0042262; P:DNA protection; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0006298; P:mismatch repair; IC:UniProtKB.
DR   GO; GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   A14EL_HUMAN             Reviewed;         152 AA.
AC   P0DKL9;
DE   RecName: Full=ARL14 effector protein-like;
GN   Name=ARL14EPL;
//
ID   A16A1_HUMAN             Reviewed;         802 AA.
AC   Q8IZ83; B4DLQ1; C9JBH6; Q86YF0; Q8IYL4; Q8TEI8;
DE   RecName: Full=Aldehyde dehydrogenase family 16 member A1;
GN   Name=ALDH16A1;
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
//
ID   A16L1_HUMAN             Reviewed;         607 AA.
AC   Q676U5; A3EXK9; A3EXL0; B6ZDH0; Q6IPN1; Q6UXW4; Q6ZVZ5; Q8NCY2;
AC   Q96JV5; Q9H619;
DE   RecName: Full=Autophagy-related protein 16-1;
DE   AltName: Full=APG16-like 1;
GN   Name=ATG16L1; Synonyms=APG16L; ORFNames=UNQ9393/PRO34307;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; NAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   A16L2_HUMAN             Reviewed;         619 AA.
AC   Q8NAA4; A5PL30; B2RPK5; Q658V4; Q6PID3; Q8NBG0;
DE   RecName: Full=Autophagy-related protein 16-2;
DE   AltName: Full=APG16-like 2;
DE   AltName: Full=WD repeat-containing protein 80;
GN   Name=ATG16L2; Synonyms=WDR80;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   A1AG1_HUMAN             Reviewed;         201 AA.
AC   P02763; B7ZKQ5; Q5T539; Q5U067; Q8TC16;
DE   RecName: Full=Alpha-1-acid glycoprotein 1;
DE            Short=AGP 1;
DE   AltName: Full=Orosomucoid-1;
DE            Short=OMD 1;
DE   Flags: Precursor;
GN   Name=ORM1; Synonyms=AGP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006953; P:acute-phase response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0002682; P:regulation of immune system process; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   A1AG2_HUMAN             Reviewed;         201 AA.
AC   P19652; B2R5L2; Q16571; Q5T538; Q6IB74;
DE   RecName: Full=Alpha-1-acid glycoprotein 2;
DE            Short=AGP 2;
DE   AltName: Full=Orosomucoid-2;
DE            Short=OMD 2;
DE   Flags: Precursor;
GN   Name=ORM2; Synonyms=AGP2;
DR   GO; GO:0006953; P:acute-phase response; TAS:ProtInc.
DR   GO; GO:0002682; P:regulation of immune system process; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   A1ATR_HUMAN             Reviewed;         420 AA.
AC   P20848;
DE   RecName: Full=Putative alpha-1-antitrypsin-related protein;
DE   AltName: Full=Protease inhibitor 1-like;
DE   AltName: Full=Serpin A2;
DE   Flags: Precursor;
GN   Name=SERPINA2; Synonyms=ARGS, ATR, PIL, SERPINA2P;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   A1AT_HUMAN              Reviewed;         418 AA.
AC   P01009; A6PX14; B2RDQ8; Q0PVP5; Q13672; Q53XB8; Q5U0M1; Q7M4R2;
AC   Q86U18; Q86U19; Q96BF9; Q96ES1; Q9P1P0; Q9UCE6; Q9UCM3;
DE   RecName: Full=Alpha-1-antitrypsin;
DE   AltName: Full=Alpha-1 protease inhibitor;
DE   AltName: Full=Alpha-1-antiproteinase;
DE   AltName: Full=Serpin A1;
DE   Contains:
DE     RecName: Full=Short peptide from AAT;
DE              Short=SPAAT;
DE   Flags: Precursor;
GN   Name=SERPINA1; Synonyms=AAT, PI; ORFNames=PRO0684, PRO2209;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0046687; P:response to chromate; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0033986; P:response to methanol; IEA:Ensembl.
DR   GO; GO:0034014; P:response to triglyceride; IEA:Ensembl.
//
ID   A1BG_HUMAN              Reviewed;         495 AA.
AC   P04217; A8K052; Q68CK0; Q8IYJ6; Q96P39;
DE   RecName: Full=Alpha-1B-glycoprotein;
DE   AltName: Full=Alpha-1-B glycoprotein;
DE   Flags: Precursor;
GN   Name=A1BG;
//
ID   A1CF_HUMAN              Reviewed;         594 AA.
AC   Q9NQ94; A1L4F2; A8K7G7; B7ZM14; Q5SZQ0; Q9NQ93; Q9NQX8; Q9NQX9;
AC   Q9NXC9; Q9NZD3;
DE   RecName: Full=APOBEC1 complementation factor;
DE   AltName: Full=APOBEC1-stimulating protein;
GN   Name=A1CF; Synonyms=ACF, ASP;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0016554; P:cytidine to uridine editing; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016556; P:mRNA modification; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
//
ID   A20A1_HUMAN             Reviewed;         823 AA.
AC   Q5TYW2; Q9H0H6;
DE   RecName: Full=Ankyrin repeat domain-containing protein 20A1;
GN   Name=ANKRD20A1; Synonyms=ANKRD20A;
//
ID   A20A2_HUMAN             Reviewed;         823 AA.
AC   Q5SQ80;
DE   RecName: Full=Ankyrin repeat domain-containing protein 20A2;
GN   Name=ANKRD20A2;
//
ID   A20A3_HUMAN             Reviewed;         823 AA.
AC   Q5VUR7;
DE   RecName: Full=Ankyrin repeat domain-containing protein 20A3;
GN   Name=ANKRD20A3;
//
ID   A20A4_HUMAN             Reviewed;         823 AA.
AC   Q4UJ75;
DE   RecName: Full=Ankyrin repeat domain-containing protein 20A4;
GN   Name=ANKRD20A4;
//
ID   A20A5_HUMAN             Reviewed;         165 AA.
AC   A0PJZ0; Q4G1B6;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 20A5;
DE   AltName: Full=Ankyrin repeat domain-containing protein 20A5 pseudogene;
GN   Name=ANKRD20A5P; Synonyms=ANKRD20A5;
//
ID   A26L1_HUMAN             Reviewed;         119 AA.
AC   Q96IX9;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 26-like 1;
DE   AltName: Full=Ankyrin repeat domain-containing protein 36B pseudogene 1;
GN   Name=ANKRD36BP1; Synonyms=ANKRD26L1;
//
ID   A2AP_HUMAN              Reviewed;         491 AA.
AC   P08697; B4E1B7; Q8N5U7; Q9UCG2; Q9UCG3;
DE   RecName: Full=Alpha-2-antiplasmin;
DE            Short=Alpha-2-AP;
DE   AltName: Full=Alpha-2-plasmin inhibitor;
DE            Short=Alpha-2-PI;
DE   AltName: Full=Serpin F2;
DE   Flags: Precursor;
GN   Name=SERPINF2; Synonyms=AAP, PLI;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048514; P:blood vessel morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030199; P:collagen fibril organization; ISS:BHF-UCL.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0010757; P:negative regulation of plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IDA:BHF-UCL.
DR   GO; GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; TAS:BHF-UCL.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0071636; P:positive regulation of transforming growth factor beta production; IDA:BHF-UCL.
DR   GO; GO:0002034; P:regulation of blood vessel size by renin-angiotensin; ISS:BHF-UCL.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
//
ID   A2GL_HUMAN              Reviewed;         347 AA.
AC   P02750; Q8N4F5; Q96QZ4;
DE   RecName: Full=Leucine-rich alpha-2-glycoprotein;
DE            Short=LRG;
DE   Flags: Precursor;
GN   Name=LRG1; Synonyms=LRG;
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
//
ID   A2MG_HUMAN              Reviewed;        1474 AA.
AC   P01023; Q13677; Q59F47; Q5QTS0; Q68DN2; Q6PIY3; Q6PN97;
DE   RecName: Full=Alpha-2-macroglobulin;
DE            Short=Alpha-2-M;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5;
DE   Flags: Precursor;
GN   Name=A2M; Synonyms=CPAMD5; ORFNames=FWP007;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0019838; F:growth factor binding; IDA:UniProtKB.
DR   GO; GO:0019966; F:interleukin-1 binding; IDA:UniProtKB.
DR   GO; GO:0019959; F:interleukin-8 binding; IPI:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0043120; F:tumor necrosis factor binding; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001869; P:negative regulation of complement activation, lectin pathway; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
//
ID   A2ML1_HUMAN             Reviewed;        1454 AA.
AC   A8K2U0; B5MDD1; Q2M224; Q6ZW52; Q6ZW53; Q8N1M4; Q96LQ8;
DE   RecName: Full=Alpha-2-macroglobulin-like protein 1;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9;
DE   Flags: Precursor;
GN   Name=A2ML1; Synonyms=CPAMD9;
DR   GO; GO:0030414; F:peptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0052548; P:regulation of endopeptidase activity; IDA:UniProtKB.
//
ID   A30BL_HUMAN             Reviewed;         258 AA.
AC   A7E2S9; B8ZZL7;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 30B-like;
GN   Name=ANKRD30BL; Synonyms=NCRNA00164;
//
ID   A4AS1_HUMAN             Reviewed;         129 AA.
AC   Q5T5F5; Q6ZS69;
DE   RecName: Full=Uncharacterized protein ADAMTSL4-AS1;
DE   AltName: Full=ADAMTSL4 antisense RNA 1;
DE   AltName: Full=ADAMTSL4 antisense gene protein 1;
GN   Name=ADAMTSL4-AS1; Synonyms=C1orf138;
//
ID   A4GAT_HUMAN             Reviewed;         353 AA.
AC   Q9NPC4; B2R7C4; Q9P1X5;
DE   RecName: Full=Lactosylceramide 4-alpha-galactosyltransferase;
DE            EC=2.4.1.228;
DE   AltName: Full=Alpha-1,4-N-acetylglucosaminyltransferase;
DE   AltName: Full=Alpha-1,4-galactosyltransferase;
DE   AltName: Full=Alpha4Gal-T1;
DE   AltName: Full=CD77 synthase;
DE   AltName: Full=Globotriaosylceramide synthase;
DE            Short=Gb3 synthase;
DE   AltName: Full=P1/Pk synthase;
DE   AltName: Full=UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase;
GN   Name=A4GALT; Synonyms=A14GALT, A4GALT1;
DR   GO; GO:0008378; F:galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0050512; F:lactosylceramide 4-alpha-galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0007009; P:plasma membrane organization; IDA:MGI.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   A4GCT_HUMAN             Reviewed;         340 AA.
AC   Q9UNA3; Q0VDK1; Q0VDK2;
DE   RecName: Full=Alpha-1,4-N-acetylglucosaminyltransferase;
DE            Short=Alpha4GnT;
DE            EC=2.4.1.-;
GN   Name=A4GNT;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IDA:MGI.
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IDA:MGI.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0006493; P:protein O-linked glycosylation; TAS:ProtInc.
//
ID   A4_HUMAN                Reviewed;         770 AA.
AC   P05067; B2R5V1; B4DII8; D3DSD1; D3DSD2; D3DSD3; P09000; P78438;
AC   Q13764; Q13778; Q13793; Q16011; Q16014; Q16019; Q16020; Q6GSC0;
AC   Q8WZ99; Q9BT38; Q9UC33; Q9UCA9; Q9UCB6; Q9UCC8; Q9UCD1; Q9UQ58;
DE   RecName: Full=Amyloid beta A4 protein;
DE   AltName: Full=ABPP;
DE   AltName: Full=APPI;
DE            Short=APP;
DE   AltName: Full=Alzheimer disease amyloid protein;
DE   AltName: Full=Cerebral vascular amyloid peptide;
DE            Short=CVAP;
DE   AltName: Full=PreA4;
DE   AltName: Full=Protease nexin-II;
DE            Short=PN-II;
DE   Contains:
DE     RecName: Full=N-APP;
DE   Contains:
DE     RecName: Full=Soluble APP-alpha;
DE              Short=S-APP-alpha;
DE   Contains:
DE     RecName: Full=Soluble APP-beta;
DE              Short=S-APP-beta;
DE   Contains:
DE     RecName: Full=C99;
DE   Contains:
DE     RecName: Full=Beta-amyloid protein 42;
DE     AltName: Full=Beta-APP42;
DE   Contains:
DE     RecName: Full=Beta-amyloid protein 40;
DE     AltName: Full=Beta-APP40;
DE   Contains:
DE     RecName: Full=C83;
DE   Contains:
DE     RecName: Full=P3(42);
DE   Contains:
DE     RecName: Full=P3(40);
DE   Contains:
DE     RecName: Full=C80;
DE   Contains:
DE     RecName: Full=Gamma-secretase C-terminal fragment 59;
DE     AltName: Full=Amyloid intracellular domain 59;
DE              Short=AICD-59;
DE              Short=AID(59);
DE     AltName: Full=Gamma-CTF(59);
DE   Contains:
DE     RecName: Full=Gamma-secretase C-terminal fragment 57;
DE     AltName: Full=Amyloid intracellular domain 57;
DE              Short=AICD-57;
DE              Short=AID(57);
DE     AltName: Full=Gamma-CTF(57);
DE   Contains:
DE     RecName: Full=Gamma-secretase C-terminal fragment 50;
DE     AltName: Full=Amyloid intracellular domain 50;
DE              Short=AICD-50;
DE              Short=AID(50);
DE     AltName: Full=Gamma-CTF(50);
DE   Contains:
DE     RecName: Full=C31;
DE   Flags: Precursor;
GN   Name=APP; Synonyms=A4, AD1;
DR   GO; GO:0033130; F:acetylcholine receptor binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0016504; F:peptidase activator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051425; F:PTB domain binding; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0008344; P:adult locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0008088; P:axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0016199; P:axon midline choice point recognition; ISS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0048669; P:collateral sprouting in absence of injury; ISS:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; ISS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; ISS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0007617; P:mating behavior; ISS:UniProtKB.
DR   GO; GO:0000085; P:mitotic G2 phase; ISS:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; ISS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0016322; P:neuron remodeling; ISS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0051563; P:smooth endoplasmic reticulum calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0051124; P:synaptic growth at neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; ISS:UniProtKB.
//
ID   A7L3B_HUMAN             Reviewed;          97 AA.
AC   Q96GX2;
DE   RecName: Full=Putative ataxin-7-like protein 3B;
GN   Name=ATXN7L3B;
//
ID   AA1R_HUMAN              Reviewed;         326 AA.
AC   P30542; A6NFY5; A6NGP4; A8K1L3; B3KXQ4; D2CGD0; Q6FHK3; Q8TAM8;
DE   RecName: Full=Adenosine receptor A1;
GN   Name=ADORA1;
DR   GuidetoPHARMACOLOGY; 18; -.
DR   GO; GO:0001609; F:G-protein coupled adenosine receptor activity; IEA:InterPro.
DR   GO; GO:0004629; F:phospholipase C activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001883; F:purine nucleoside binding; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0050890; P:cognition; IEA:Ensembl.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0055118; P:negative regulation of cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042323; P:negative regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0045822; P:negative regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0002686; P:negative regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0070256; P:negative regulation of mucus secretion; IEA:Ensembl.
DR   GO; GO:0032900; P:negative regulation of neurotrophin production; IEA:Ensembl.
DR   GO; GO:0035814; P:negative regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0045908; P:negative regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006909; P:phagocytosis; TAS:ProtInc.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IEA:Ensembl.
DR   GO; GO:0032244; P:positive regulation of nucleoside transport; IEA:Ensembl.
DR   GO; GO:0002793; P:positive regulation of peptide secretion; IEA:Ensembl.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006612; P:protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0003093; P:regulation of glomerular filtration; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0060087; P:relaxation of vascular smooth muscle; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
//
ID   AA2AR_HUMAN             Reviewed;         412 AA.
AC   P29274; B2R7E0;
DE   RecName: Full=Adenosine receptor A2a;
GN   Name=ADORA2A; Synonyms=ADORA2;
DR   GuidetoPHARMACOLOGY; 19; -.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0001609; F:G-protein coupled adenosine receptor activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0048143; P:astrocyte activation; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0006171; P:cAMP biosynthetic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0046636; P:negative regulation of alpha-beta T cell activation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0040013; P:negative regulation of locomotion; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006909; P:phagocytosis; TAS:ProtInc.
DR   GO; GO:0014057; P:positive regulation of acetylcholine secretion, neurotransmission; IEA:Ensembl.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045938; P:positive regulation of circadian sleep/wake cycle, sleep; IEA:Ensembl.
DR   GO; GO:0014049; P:positive regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0035810; P:positive regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:0014061; P:regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:Reactome.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   AA2BR_HUMAN             Reviewed;         332 AA.
AC   P29275;
DE   RecName: Full=Adenosine receptor A2b;
GN   Name=ADORA2B;
DR   GuidetoPHARMACOLOGY; 20; -.
DR   GO; GO:0001609; F:G-protein coupled adenosine receptor activity; IEA:InterPro.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IEA:Ensembl.
DR   GO; GO:0002882; P:positive regulation of chronic inflammatory response to non-antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IEA:Ensembl.
DR   GO; GO:0060087; P:relaxation of vascular smooth muscle; IEA:Ensembl.
//
ID   AA3RB_HUMAN             Reviewed;         266 AA.
AC   Q6P2N6; Q5QNY7;
DE   RecName: Full=Protein ADORA3, isoform 3;
GN   Name=ADORA3; ORFNames=UNQ1931/PRO4406;
//
ID   AA3R_HUMAN              Reviewed;         318 AA.
AC   P33765; A2A3P4; Q6UWU0; Q9BYZ1;
DE   RecName: Full=Adenosine receptor A3;
GN   Name=ADORA3; ORFNames=UNQ1931/PRO4406;
DR   GuidetoPHARMACOLOGY; 21; -.
DR   GO; GO:0001609; F:G-protein coupled adenosine receptor activity; IEA:Ensembl.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0002553; P:histamine secretion by mast cell; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0070257; P:positive regulation of mucus secretion; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   AAA1_HUMAN              Reviewed;         523 AA.
AC   Q9NS82; B2RE84;
DE   RecName: Full=Asc-type amino acid transporter 1;
DE            Short=Asc-1;
DE   AltName: Full=Solute carrier family 7 member 10;
GN   Name=SLC7A10; Synonyms=ASC1;
DR   GO; GO:0015194; F:L-serine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0042941; P:D-alanine transport; IEA:Ensembl.
DR   GO; GO:0042942; P:D-serine transport; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015825; P:L-serine transport; TAS:GOC.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0015804; P:neutral amino acid transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AAAD_HUMAN              Reviewed;         399 AA.
AC   P22760; A8K3L3; D3DNJ6; Q8N1A9;
DE   RecName: Full=Arylacetamide deacetylase;
DE            EC=3.1.1.3;
GN   Name=AADAC; Synonyms=DAC;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0019213; F:deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0016298; F:lipase activity; TAS:UniProtKB.
DR   GO; GO:0017171; F:serine hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0004806; F:triglyceride lipase activity; ISS:UniProtKB.
DR   GO; GO:0010898; P:positive regulation of triglyceride catabolic process; ISS:UniProtKB.
//
ID   AAAS_HUMAN              Reviewed;         546 AA.
AC   Q9NRG9; Q5JB47; Q9NWI6; Q9UG19;
DE   RecName: Full=Aladin;
DE   AltName: Full=Adracalin;
GN   Name=AAAS; Synonyms=ADRACALA; ORFNames=GL003;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AAAT_HUMAN              Reviewed;         541 AA.
AC   Q15758; A8K9H5; B4DR77; B4DWS4; B7ZB81; D0EYG6; E9PC01; O95720;
AC   Q96RL9; Q9BWQ3; Q9UNP2;
DE   RecName: Full=Neutral amino acid transporter B(0);
DE            Short=ATB(0);
DE   AltName: Full=Baboon M7 virus receptor;
DE   AltName: Full=RD114/simian type D retrovirus receptor;
DE   AltName: Full=Sodium-dependent neutral amino acid transporter type 2;
DE   AltName: Full=Solute carrier family 1 member 5;
GN   Name=SLC1A5; Synonyms=ASCT2, M7V1, RDR, RDRC;
DR   GuidetoPHARMACOLOGY; 874; -.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; TAS:BHF-UCL.
DR   GO; GO:0015194; F:L-serine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006860; P:extracellular amino acid transport; IEA:Ensembl.
DR   GO; GO:0006868; P:glutamine transport; TAS:BHF-UCL.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015804; P:neutral amino acid transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AACS_HUMAN              Reviewed;         672 AA.
AC   Q86V21; Q49AB9; Q49AC3; Q658Q8; Q8IWD2; Q8NEW5; Q9BSJ9; Q9H829;
AC   Q9HA19;
DE   RecName: Full=Acetoacetyl-CoA synthetase;
DE            EC=6.2.1.16;
DE   AltName: Full=Acyl-CoA synthetase family member 1;
DE   AltName: Full=Protein sur-5 homolog;
GN   Name=AACS; Synonyms=ACSF1;
DR   GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IEA:Ensembl.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0071397; P:cellular response to cholesterol; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071394; P:cellular response to testosterone stimulus; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0034201; P:response to oleic acid; IEA:Ensembl.
DR   GO; GO:0014074; P:response to purine-containing compound; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0050872; P:white fat cell differentiation; IEA:Ensembl.
//
ID   AACT_HUMAN              Reviewed;         423 AA.
AC   P01011; B3KVQ7; Q13703; Q2TU87; Q2TU88; Q59GP9; Q6LBY8; Q6LDT7;
AC   Q6NSC9; Q8N177; Q96DW8; Q9UC47; Q9UNU9;
DE   RecName: Full=Alpha-1-antichymotrypsin;
DE            Short=ACT;
DE   AltName: Full=Cell growth-inhibiting gene 24/25 protein;
DE   AltName: Full=Serpin A3;
DE   Contains:
DE     RecName: Full=Alpha-1-antichymotrypsin His-Pro-less;
DE   Flags: Precursor;
GN   Name=SERPINA3; Synonyms=AACT; ORFNames=GIG24, GIG25;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; NAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   AADAT_HUMAN             Reviewed;         425 AA.
AC   Q8N5Z0; B3KP84; Q9UL02;
DE   RecName: Full=Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial;
DE            Short=KAT/AadAT;
DE   AltName: Full=2-aminoadipate aminotransferase;
DE   AltName: Full=2-aminoadipate transaminase;
DE            EC=2.6.1.39;
DE   AltName: Full=Alpha-aminoadipate aminotransferase;
DE            Short=AadAT;
DE   AltName: Full=Kynurenine aminotransferase II;
DE   AltName: Full=Kynurenine--oxoglutarate aminotransferase II;
DE   AltName: Full=Kynurenine--oxoglutarate transaminase 2;
DE            EC=2.6.1.7;
DE   AltName: Full=Kynurenine--oxoglutarate transaminase II;
DE   Flags: Precursor;
GN   Name=AADAT; Synonyms=KAT2;
DR   GO; GO:0047536; F:2-aminoadipate transaminase activity; IDA:UniProtKB.
DR   GO; GO:0016212; F:kynurenine-oxoglutarate transaminase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:Ensembl.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IDA:UniProtKB.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0070189; P:kynurenine metabolic process; IDA:UniProtKB.
DR   GO; GO:0097052; P:L-kynurenine metabolic process; IDA:GOC.
DR   GO; GO:0033512; P:L-lysine catabolic process to acetyl-CoA via saccharopine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:Ensembl.
//
ID   AAED1_HUMAN             Reviewed;         226 AA.
AC   Q7RTV5; B2RMW4; Q5JU02;
DE   RecName: Full=Thioredoxin-like protein AAED1;
DE   AltName: Full=AhpC/TSA antioxidant enzyme domain-containing protein 1;
GN   Name=AAED1; Synonyms=C9orf21;
//
ID   AAGAB_HUMAN             Reviewed;         315 AA.
AC   Q6PD74; B4DG44; Q6FI86; Q7Z5X9; Q9H0P1; Q9HAK0;
DE   RecName: Full=Alpha- and gamma-adaptin-binding protein p34;
GN   Name=AAGAB;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AAK1_HUMAN              Reviewed;         961 AA.
AC   Q2M2I8; Q4ZFZ3; Q53RX6; Q9UPV4;
DE   RecName: Full=AP2-associated protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Adaptor-associated kinase 1;
GN   Name=AAK1; Synonyms=KIAA1048;
DR   GuidetoPHARMACOLOGY; 1921; -.
DR   GO; GO:0035612; F:AP-2 adaptor complex binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005112; F:Notch binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:UniProtKB.
//
ID   AAKB1_HUMAN             Reviewed;         270 AA.
AC   Q9Y478; Q9UBV0; Q9UE20; Q9UEX2; Q9Y6V8;
DE   RecName: Full=5'-AMP-activated protein kinase subunit beta-1;
DE            Short=AMPK subunit beta-1;
DE            Short=AMPKb;
GN   Name=PRKAB1; Synonyms=AMPK;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   AAKB2_HUMAN             Reviewed;         272 AA.
AC   O43741; A8K9V5; Q5VXY0;
DE   RecName: Full=5'-AMP-activated protein kinase subunit beta-2;
DE            Short=AMPK subunit beta-2;
GN   Name=PRKAB2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AAKG1_HUMAN             Reviewed;         331 AA.
AC   P54619; B4DDT7; Q8N7V9;
DE   RecName: Full=5'-AMP-activated protein kinase subunit gamma-1;
DE            Short=AMPK gamma1;
DE            Short=AMPK subunit gamma-1;
DE            Short=AMPKg;
GN   Name=PRKAG1;
DR   GO; GO:0043531; F:ADP binding; ISS:UniProtKB.
DR   GO; GO:0016208; F:AMP binding; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IDA:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; TAS:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006110; P:regulation of glycolytic process; TAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   AAKG2_HUMAN             Reviewed;         569 AA.
AC   Q9UGJ0; Q53Y07; Q6NUI0; Q75MP4; Q9NUZ9; Q9UDN8; Q9ULX8;
DE   RecName: Full=5'-AMP-activated protein kinase subunit gamma-2;
DE            Short=AMPK gamma2;
DE            Short=AMPK subunit gamma-2;
DE   AltName: Full=H91620p;
GN   Name=PRKAG2;
DR   GO; GO:0043531; F:ADP binding; IDA:BHF-UCL.
DR   GO; GO:0016208; F:AMP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; IMP:BHF-UCL.
DR   GO; GO:0008607; F:phosphorylase kinase regulator activity; IMP:BHF-UCL.
DR   GO; GO:0030295; F:protein kinase activator activity; IMP:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IDA:BHF-UCL.
DR   GO; GO:0006754; P:ATP biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0005977; P:glycogen metabolic process; IMP:BHF-UCL.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:BHF-UCL.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:GOC.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0046320; P:regulation of fatty acid oxidation; TAS:BHF-UCL.
DR   GO; GO:0046324; P:regulation of glucose import; TAS:BHF-UCL.
DR   GO; GO:0006110; P:regulation of glycolytic process; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016126; P:sterol biosynthetic process; TAS:BHF-UCL.
//
ID   AAKG3_HUMAN             Reviewed;         489 AA.
AC   Q9UGI9; Q4QQG8; Q4V779; Q9NRL1;
DE   RecName: Full=5'-AMP-activated protein kinase subunit gamma-3;
DE            Short=AMPK gamma3;
DE            Short=AMPK subunit gamma-3;
GN   Name=PRKAG3; Synonyms=AMPKG3;
DR   GO; GO:0004679; F:AMP-activated protein kinase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019901; F:protein kinase binding; IDA:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:GOC.
//
ID   AAMDC_HUMAN             Reviewed;         122 AA.
AC   Q9H7C9; Q96AQ4; Q9Y6B1;
DE   RecName: Full=Mth938 domain-containing protein;
DE   AltName: Full=Adipogenesis associated Mth938 domain-containing protein;
GN   Name=AAMDC; Synonyms=C11orf67; ORFNames=PTD015;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
//
ID   AAMP_HUMAN              Reviewed;         434 AA.
AC   Q13685; Q8WUJ9; Q96H92;
DE   RecName: Full=Angio-associated migratory cell protein;
GN   Name=AAMP;
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.
DR   GO; GO:0014909; P:smooth muscle cell migration; IEP:UniProtKB.
//
ID   AAPK1_HUMAN             Reviewed;         559 AA.
AC   Q13131; A8MTQ6; B2R7E1; O00286; Q5D0E1; Q86VS1; Q9UNQ4;
DE   RecName: Full=5'-AMP-activated protein kinase catalytic subunit alpha-1;
DE            Short=AMPK subunit alpha-1;
DE            EC=2.7.11.1;
DE   AltName: Full=Acetyl-CoA carboxylase kinase;
DE            Short=ACACA kinase;
DE            EC=2.7.11.27;
DE   AltName: Full=Hydroxymethylglutaryl-CoA reductase kinase;
DE            Short=HMGCR kinase;
DE            EC=2.7.11.31;
DE   AltName: Full=Tau-protein kinase PRKAA1;
DE            EC=2.7.11.26;
GN   Name=PRKAA1; Synonyms=AMPK1;
DR   GuidetoPHARMACOLOGY; 1541; -.
DR   GO; GO:0050405; F:[acetyl-CoA carboxylase] kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047322; F:[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000187; P:activation of MAPK activity; NAS:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009631; P:cold acclimation; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.
DR   GO; GO:0019395; P:fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008610; P:lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:2001274; P:negative regulation of glucose import in response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0046318; P:negative regulation of glucosylceramide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045542; P:positive regulation of cholesterol biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; ISS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060627; P:regulation of vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; ISS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; NAS:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AAPK2_HUMAN             Reviewed;         552 AA.
AC   P54646; Q9H1E8; Q9UD43;
DE   RecName: Full=5'-AMP-activated protein kinase catalytic subunit alpha-2;
DE            Short=AMPK subunit alpha-2;
DE            EC=2.7.11.1;
DE   AltName: Full=Acetyl-CoA carboxylase kinase;
DE            Short=ACACA kinase;
DE            EC=2.7.11.27;
DE   AltName: Full=Hydroxymethylglutaryl-CoA reductase kinase;
DE            Short=HMGCR kinase;
DE            EC=2.7.11.31;
GN   Name=PRKAA2; Synonyms=AMPK, AMPK2;
DR   GuidetoPHARMACOLOGY; 1542; -.
DR   GO; GO:0050405; F:[acetyl-CoA carboxylase] kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047322; F:[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.
DR   GO; GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008610; P:lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; ISS:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AAR2_HUMAN              Reviewed;         384 AA.
AC   Q9Y312; E1P5S7; Q9H4F9; Q9P1P3; Q9UFK9;
DE   RecName: Full=Protein AAR2 homolog;
DE   AltName: Full=AAR2 splicing factor homolog;
GN   Name=AAR2; Synonyms=C20orf4; ORFNames=CGI-23, PRO0225;
//
ID   AARD_HUMAN              Reviewed;         155 AA.
AC   Q4LEZ3; A5PKU8;
DE   RecName: Full=Alanine and arginine-rich domain-containing protein;
GN   Name=AARD; Synonyms=C8orf85;
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
//
ID   AAS1_HUMAN              Reviewed;         159 AA.
AC   P86434;
DE   RecName: Full=Putative uncharacterized protein ADORA2A-AS1;
DE   AltName: Full=ADORA2A antisense RNA 1;
DE   AltName: Full=ADORA2A antisense gene protein 1;
GN   Name=ADORA2A-AS1; Synonyms=C22orf45;
//
ID   AASD1_HUMAN             Reviewed;         412 AA.
AC   Q9BTE6; B4DI73;
DE   RecName: Full=Alanyl-tRNA editing protein Aarsd1;
DE   AltName: Full=Alanyl-tRNA synthetase domain-containing protein 1;
GN   Name=AARSD1;
DR   GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0002196; F:Ser-tRNA(Ala) hydrolase activity; IEA:Ensembl.
DR   GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
//
ID   AASS_HUMAN              Reviewed;         926 AA.
AC   Q9UDR5; O95462;
DE   RecName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial;
DE   AltName: Full=LKR/SDH;
DE   Includes:
DE     RecName: Full=Lysine ketoglutarate reductase;
DE              Short=LKR;
DE              Short=LOR;
DE              EC=1.5.1.8;
DE   Includes:
DE     RecName: Full=Saccharopine dehydrogenase;
DE              Short=SDH;
DE              EC=1.5.1.9;
DE   Flags: Precursor;
GN   Name=AASS;
DR   GO; GO:0047131; F:saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity; NAS:UniProtKB.
DR   GO; GO:0047130; F:saccharopine dehydrogenase (NADP+, L-lysine-forming) activity; EXP:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0033512; P:L-lysine catabolic process to acetyl-CoA via saccharopine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006554; P:lysine catabolic process; NAS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AATC2_HUMAN             Reviewed;         421 AA.
AC   Q8NHS2; A8MWL4;
DE   RecName: Full=Putative aspartate aminotransferase, cytoplasmic 2;
DE            EC=2.6.1.-;
DE   AltName: Full=Glutamate oxaloacetate transaminase 1-like protein 1;
DE   AltName: Full=Transaminase A-like protein 1;
GN   Name=GOT1L1;
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
//
ID   AATC_HUMAN              Reviewed;         413 AA.
AC   P17174; B2R6R7; Q5VW80;
DE   RecName: Full=Aspartate aminotransferase, cytoplasmic;
DE            Short=cAspAT;
DE            EC=2.6.1.1;
DE            EC=2.6.1.3;
DE   AltName: Full=Cysteine aminotransferase, cytoplasmic;
DE   AltName: Full=Cysteine transaminase, cytoplasmic;
DE            Short=cCAT;
DE   AltName: Full=Glutamate oxaloacetate transaminase 1;
DE   AltName: Full=Transaminase A;
GN   Name=GOT1;
DR   GO; GO:0031406; F:carboxylic acid binding; IEA:Ensembl.
DR   GO; GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IDA:UniProtKB.
DR   GO; GO:0047801; F:L-cysteine:2-oxoglutarate aminotransferase activity; ISS:UniProtKB.
DR   GO; GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:Ensembl.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; TAS:Reactome.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.
DR   GO; GO:0006532; P:aspartate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006533; P:aspartate catabolic process; IDA:UniProtKB.
DR   GO; GO:0006531; P:aspartate metabolic process; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEP:UniProtKB.
DR   GO; GO:0055089; P:fatty acid homeostasis; IEA:Ensembl.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0019551; P:glutamate catabolic process to 2-oxoglutarate; IEA:Ensembl.
DR   GO; GO:0019550; P:glutamate catabolic process to aspartate; IEA:Ensembl.
DR   GO; GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.
DR   GO; GO:0006114; P:glycerol biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; TAS:Reactome.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0051384; P:response to glucocorticoid; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   AATF_HUMAN              Reviewed;         560 AA.
AC   Q9NY61; A6NCJ6; B3KQ26; Q9P0A4; Q9UNX5;
DE   RecName: Full=Protein AATF;
DE   AltName: Full=Apoptosis-antagonizing transcription factor;
DE   AltName: Full=Rb-binding protein Che-1;
GN   Name=AATF; Synonyms=CHE1, DED; ORFNames=HSPC277;
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:UniProtKB.
DR   GO; GO:0040016; P:embryonic cleavage; IEA:Ensembl.
DR   GO; GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0032929; P:negative regulation of superoxide anion generation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:Ensembl.
//
ID   AATM_HUMAN              Reviewed;         430 AA.
AC   P00505; B4DJA6; E7ERW2; Q53FL3; Q9BWA3;
DE   RecName: Full=Aspartate aminotransferase, mitochondrial;
DE            Short=mAspAT;
DE            EC=2.6.1.1;
DE            EC=2.6.1.7;
DE   AltName: Full=Fatty acid-binding protein;
DE            Short=FABP-1;
DE   AltName: Full=Glutamate oxaloacetate transaminase 2;
DE   AltName: Full=Kynurenine aminotransferase 4;
DE   AltName: Full=Kynurenine aminotransferase IV;
DE   AltName: Full=Kynurenine--oxoglutarate transaminase 4;
DE   AltName: Full=Kynurenine--oxoglutarate transaminase IV;
DE   AltName: Full=Plasma membrane-associated fatty acid-binding protein;
DE            Short=FABPpm;
DE   AltName: Full=Transaminase A;
DE   Flags: Precursor;
GN   Name=GOT2;
DR   GO; GO:0016212; F:kynurenine-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.
DR   GO; GO:0019470; P:4-hydroxyproline catabolic process; TAS:BHF-UCL.
DR   GO; GO:0006532; P:aspartate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006533; P:aspartate catabolic process; IDA:UniProtKB.
DR   GO; GO:0006531; P:aspartate metabolic process; ISS:UniProtKB.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0015908; P:fatty acid transport; IEP:UniProtKB.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0019551; P:glutamate catabolic process to 2-oxoglutarate; IEA:Ensembl.
DR   GO; GO:0019550; P:glutamate catabolic process to aspartate; IEA:Ensembl.
DR   GO; GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AB12B_HUMAN             Reviewed;         362 AA.
AC   Q7Z5M8; Q3KNR9; Q3KNS0; Q7Z5M6; Q7Z5M7; Q8N4D2;
DE   RecName: Full=Abhydrolase domain-containing protein 12B;
DE            EC=3.-.-.-;
GN   Name=ABHD12B; Synonyms=C14orf29;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   AB17A_HUMAN             Reviewed;         310 AA.
AC   Q96GS6; A8K0G8; D6W5Z9; Q6PJU2; Q8WUH9; Q9BWL0; Q9H7Q9;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 17A;
DE            EC=3.-.-.-;
DE   Flags: Precursor;
GN   Name=ABHD17A; Synonyms=C19orf27, FAM108A1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   AB17B_HUMAN             Reviewed;         288 AA.
AC   Q5VST6; A8KAJ5; Q5VST7; Q86YB6; Q8IY03; Q9Y377;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 17B;
DE            EC=3.-.-.-;
DE   Flags: Precursor;
GN   Name=ABHD17B; Synonyms=C9orf77, FAM108B1; ORFNames=CGI-67;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   AB17C_HUMAN             Reviewed;         329 AA.
AC   Q6PCB6; Q1RMD6; Q9NPM1;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 17C;
DE            EC=3.-.-.-;
GN   Name=ABHD17C; Synonyms=FAM108C1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   AB1IP_HUMAN             Reviewed;         666 AA.
AC   Q7Z5R6; Q8IWS8; Q8IZZ7;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family B member 1-interacting protein;
DE   AltName: Full=APBB1-interacting protein 1;
DE   AltName: Full=Proline-rich EVH1 ligand 1;
DE            Short=PREL-1;
DE   AltName: Full=Proline-rich protein 73;
DE   AltName: Full=Rap1-GTP-interacting adapter molecule;
DE            Short=RIAM;
DE   AltName: Full=Retinoic acid-responsive proline-rich protein 1;
DE            Short=RARP-1;
GN   Name=APBB1IP; Synonyms=PREL1, RARP1, RIAM;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   ABC3A_HUMAN             Reviewed;         199 AA.
AC   P31941; A0AVM1; Q12807; Q5JZ93; Q9UH18;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3A;
DE            Short=A3A;
DE            EC=3.5.4.-;
DE   AltName: Full=Phorbolin-1;
GN   Name=APOBEC3A;
DR   GO; GO:0004126; F:cytidine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0047844; F:deoxycytidine deaminase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071466; P:cellular response to xenobiotic stimulus; IDA:UniProtKB.
DR   GO; GO:0044356; P:clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine; IDA:UniProtKB.
DR   GO; GO:0009972; P:cytidine deamination; IDA:GOC.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0070383; P:DNA cytosine deamination; IDA:UniProtKB.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
//
ID   ABC3B_HUMAN             Reviewed;         382 AA.
AC   Q9UH17; B0QYD2; O95618; Q20WL1; Q5IFJ4; Q7Z2N3; Q7Z6D6; Q9UE74;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3B;
DE            Short=A3B;
DE            EC=3.5.4.-;
DE   AltName: Full=Phorbolin-1-related protein;
DE   AltName: Full=Phorbolin-2/3;
GN   Name=APOBEC3B;
DR   GO; GO:0047844; F:deoxycytidine deaminase activity; IMP:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IMP:GOC.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
//
ID   ABC3C_HUMAN             Reviewed;         190 AA.
AC   Q9NRW3; B2R884; Q5JZ92; Q7Z2N7; Q96F12;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3C;
DE            Short=A3C;
DE            EC=3.5.4.-;
DE   AltName: Full=APOBEC1-like;
DE   AltName: Full=Phorbolin I;
GN   Name=APOBEC3C; Synonyms=APOBEC1L, PBI;
DR   GO; GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009972; P:cytidine deamination; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ABC3D_HUMAN             Reviewed;         386 AA.
AC   Q96AK3; Q5JZ91; Q7Z2N2; Q7Z2N5; Q7Z2N6;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3D;
DE            Short=A3D;
DE            EC=3.5.4.-;
GN   Name=APOBEC3D;
DR   GO; GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0070383; P:DNA cytosine deamination; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
//
ID   ABC3F_HUMAN             Reviewed;         373 AA.
AC   Q8IUX4; B0QYD4; Q45F03; Q6ICH3; Q7Z2N2; Q7Z2N5;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3F;
DE            EC=3.5.4.-;
DE   AltName: Full=Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F;
DE            Short=A3F;
GN   Name=APOBEC3F;
DR   GO; GO:0004126; F:cytidine deaminase activity; IDA:HGNC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IDA:HGNC.
DR   GO; GO:0016553; P:base conversion or substitution editing; IDA:HGNC.
DR   GO; GO:0009972; P:cytidine deamination; IDA:GOC.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0070383; P:DNA cytosine deamination; IDA:UniProtKB.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:HGNC.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0048525; P:negative regulation of viral process; IDA:HGNC.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:HGNC.
//
ID   ABC3G_HUMAN             Reviewed;         384 AA.
AC   Q9HC16; B2RDR9; Q45F02; Q5TF77; Q7Z2N1; Q7Z2N4; Q9H9H8;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3G;
DE            EC=3.5.4.-;
DE   AltName: Full=APOBEC-related cytidine deaminase;
DE            Short=APOBEC-related protein;
DE            Short=ARCD;
DE   AltName: Full=APOBEC-related protein 9;
DE            Short=ARP-9;
DE   AltName: Full=CEM-15;
DE            Short=CEM15;
DE   AltName: Full=Deoxycytidine deaminase;
DE            Short=A3G;
GN   Name=APOBEC3G; ORFNames=MDS019;
DR   GO; GO:0004126; F:cytidine deaminase activity; TAS:HGNC.
DR   GO; GO:0047844; F:deoxycytidine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0016553; P:base conversion or substitution editing; TAS:HGNC.
DR   GO; GO:0009972; P:cytidine deamination; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0070383; P:DNA cytosine deamination; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:HGNC.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0048525; P:negative regulation of viral process; IDA:HGNC.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:HGNC.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ABC3H_HUMAN             Reviewed;         200 AA.
AC   Q6NTF7; B0QYP0; B0QYP1; B7TQM5; E9PF38; Q5JYL9; Q6IC87;
DE   RecName: Full=DNA dC->dU-editing enzyme APOBEC-3H;
DE            EC=3.5.4.-;
DE   AltName: Full=APOBEC-related protein 10;
DE            Short=ARP-10;
DE   AltName: Full=Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H;
DE            Short=A3H;
GN   Name=APOBEC3H;
DR   GO; GO:0004126; F:cytidine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009972; P:cytidine deamination; IDA:GOC.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0070383; P:DNA cytosine deamination; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0010529; P:negative regulation of transposition; IDA:UniProtKB.
DR   GO; GO:0048525; P:negative regulation of viral process; IMP:UniProtKB.
//
ID   ABCA1_HUMAN             Reviewed;        2261 AA.
AC   O95477; Q5VX33; Q96S56; Q96T85; Q9NQV4; Q9UN06; Q9UN07; Q9UN08;
AC   Q9UN09;
DE   RecName: Full=ATP-binding cassette sub-family A member 1;
DE   AltName: Full=ATP-binding cassette transporter 1;
DE            Short=ABC-1;
DE            Short=ATP-binding cassette 1;
DE   AltName: Full=Cholesterol efflux regulatory protein;
GN   Name=ABCA1; Synonyms=ABC1, CERP;
DR   GO; GO:0008509; F:anion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0034186; F:apolipoprotein A-I binding; IPI:BHF-UCL.
DR   GO; GO:0034188; F:apolipoprotein A-I receptor activity; IDA:BHF-UCL.
DR   GO; GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0015485; F:cholesterol binding; IC:BHF-UCL.
DR   GO; GO:0017127; F:cholesterol transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IC:BHF-UCL.
DR   GO; GO:0005548; F:phospholipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031267; F:small GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0019905; F:syntaxin binding; IPI:BHF-UCL.
DR   GO; GO:0038027; P:apolipoprotein A-I-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071397; P:cellular response to cholesterol; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0016197; P:endosomal transport; IDA:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0034380; P:high-density lipoprotein particle assembly; IMP:BHF-UCL.
DR   GO; GO:0050702; P:interleukin-1 beta secretion; IMP:BHF-UCL.
DR   GO; GO:0032367; P:intracellular cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0007040; P:lysosome organization; IDA:BHF-UCL.
DR   GO; GO:0010887; P:negative regulation of cholesterol storage; TAS:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0002790; P:peptide secretion; IEA:Ensembl.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IEA:Ensembl.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; IMP:BHF-UCL.
DR   GO; GO:0045332; P:phospholipid translocation; IEA:Ensembl.
DR   GO; GO:0060155; P:platelet dense granule organization; IMP:BHF-UCL.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IEA:Ensembl.
DR   GO; GO:0006497; P:protein lipidation; IEA:Ensembl.
DR   GO; GO:0032489; P:regulation of Cdc42 protein signal transduction; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEP:BHF-UCL.
DR   GO; GO:0055098; P:response to low-density lipoprotein particle; IEP:BHF-UCL.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0043691; P:reverse cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ABCA2_HUMAN             Reviewed;        2435 AA.
AC   Q9BZC7; A6NED5; Q5SPY5; Q5W9G5; Q76MW7; Q9HC28;
DE   RecName: Full=ATP-binding cassette sub-family A member 2;
DE   AltName: Full=ATP-binding cassette transporter 2;
DE            Short=ATP-binding cassette 2;
GN   Name=ABCA2; Synonyms=ABC2, KIAA1062;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEP:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0032383; P:regulation of intracellular cholesterol transport; IMP:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; TAS:UniProtKB.
DR   GO; GO:0048545; P:response to steroid hormone; IEP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; NAS:GOC.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   ABCA3_HUMAN             Reviewed;        1704 AA.
AC   Q99758; B2RU09; Q54A95; Q92473;
DE   RecName: Full=ATP-binding cassette sub-family A member 3;
DE   AltName: Full=ABC-C transporter;
DE   AltName: Full=ATP-binding cassette transporter 3;
DE            Short=ATP-binding cassette 3;
GN   Name=ABCA3; Synonyms=ABC3;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IDA:MGI.
//
ID   ABCA4_HUMAN             Reviewed;        2273 AA.
AC   P78363; O15112; O60438; O60915; Q0QD48; Q4LE31;
DE   RecName: Full=Retinal-specific ATP-binding cassette transporter;
DE   AltName: Full=ATP-binding cassette sub-family A member 4;
DE   AltName: Full=RIM ABC transporter;
DE            Short=RIM protein;
DE            Short=RmP;
DE   AltName: Full=Stargardt disease protein;
GN   Name=ABCA4; Synonyms=ABCR;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006649; P:phospholipid transfer to membrane; IEA:Ensembl.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   ABCA5_HUMAN             Reviewed;        1642 AA.
AC   Q8WWZ7; Q8IVJ2; Q96LJ1; Q96MS4; Q96PZ9; Q9NY14;
DE   RecName: Full=ATP-binding cassette sub-family A member 5;
GN   Name=ABCA5; Synonyms=KIAA1888;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0033344; P:cholesterol efflux; ISS:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; ISS:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0043691; P:reverse cholesterol transport; IC:BHF-UCL.
//
ID   ABCA6_HUMAN             Reviewed;        1617 AA.
AC   Q8N139; Q6NSH9; Q8N856; Q8WWZ6;
DE   RecName: Full=ATP-binding cassette sub-family A member 6;
GN   Name=ABCA6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   ABCA7_HUMAN             Reviewed;        2146 AA.
AC   Q8IZY2; Q96S58; Q9BZC4; Q9NR73; Q9UKP8;
DE   RecName: Full=ATP-binding cassette sub-family A member 7;
DE   AltName: Full=ABCA-SSN;
DE   AltName: Full=Autoantigen SS-N;
DE   AltName: Full=Macrophage ABC transporter;
GN   Name=ABCA7;
DR   GO; GO:0034188; F:apolipoprotein A-I receptor activity; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0005548; F:phospholipid transporter activity; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0038027; P:apolipoprotein A-I-mediated signaling pathway; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0034380; P:high-density lipoprotein particle assembly; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0017121; P:phospholipid scrambling; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCA8_HUMAN             Reviewed;        1581 AA.
AC   O94911; A1L3U3; C9JQE6; Q86WW0;
DE   RecName: Full=ATP-binding cassette sub-family A member 8;
GN   Name=ABCA8; Synonyms=KIAA0822;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IDA:MGI.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IDA:MGI.
//
ID   ABCA9_HUMAN             Reviewed;        1624 AA.
AC   Q8IUA7; Q6P655; Q8N2S4; Q8WWZ5; Q96MD8;
DE   RecName: Full=ATP-binding cassette sub-family A member 9;
GN   Name=ABCA9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   ABCAA_HUMAN             Reviewed;        1543 AA.
AC   Q8WWZ4; C9JZH2; C9K035; Q6PIQ6; Q7Z2I9; Q7Z7P7; Q86TD2;
DE   RecName: Full=ATP-binding cassette sub-family A member 10;
GN   Name=ABCA10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   ABCAB_HUMAN             Reviewed;         156 AA.
AC   Q4W5N1; Q9H7T1;
DE   RecName: Full=Putative ATP-binding cassette sub-family A member 11;
GN   Name=ABCA11P; Synonyms=ABCA11;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
//
ID   ABCAC_HUMAN             Reviewed;        2595 AA.
AC   Q86UK0; Q53QE2; Q53S55; Q8IZW6; Q96JT3; Q9Y4M5;
DE   RecName: Full=ATP-binding cassette sub-family A member 12;
DE   AltName: Full=ATP-binding cassette transporter 12;
DE            Short=ATP-binding cassette 12;
GN   Name=ABCA12; Synonyms=ABC12;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0019725; P:cellular homeostasis; NAS:UniProtKB.
DR   GO; GO:0035627; P:ceramide transport; IEA:Ensembl.
DR   GO; GO:0061436; P:establishment of skin barrier; IEA:Ensembl.
DR   GO; GO:0031424; P:keratinization; IEA:Ensembl.
DR   GO; GO:0055088; P:lipid homeostasis; IEA:Ensembl.
DR   GO; GO:0006869; P:lipid transport; NAS:UniProtKB.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
//
ID   ABCAD_HUMAN             Reviewed;        5058 AA.
AC   Q86UQ4; K9LC76; K9LC79; K9LCX7; K9LDK8; K9LDY4; Q6ZTT7; Q86WI2;
AC   Q8N248;
DE   RecName: Full=ATP-binding cassette sub-family A member 13;
GN   Name=ABCA13;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   ABCB5_HUMAN             Reviewed;         812 AA.
AC   Q2M3G0; A4D131; A7BKA4; B5MD19; B7WPL1; F8QQP8; J3KQ04; Q2M3I5;
AC   Q5I5Q7; Q5I5Q8; Q6KG50; Q6XFQ5; Q8IXA1;
DE   RecName: Full=ATP-binding cassette sub-family B member 5;
DE   AltName: Full=ABCB5 P-gp;
DE   AltName: Full=P-glycoprotein ABCB5;
GN   Name=ABCB5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; IDA:UniProtKB.
//
ID   ABCB6_HUMAN             Reviewed;         842 AA.
AC   Q9NP58; O75542; Q49A66; Q59GQ5; Q6ZME6; Q96ME8; Q9HAQ6; Q9HAQ7;
DE   RecName: Full=ATP-binding cassette sub-family B member 6, mitochondrial;
DE   AltName: Full=Mitochondrial ABC transporter 3;
DE            Short=Mt-ABC transporter 3;
DE   AltName: Full=P-glycoprotein-related protein;
DE   AltName: Full=Ubiquitously-expressed mammalian ABC half transporter;
GN   Name=ABCB6; Synonyms=MTABC3, PRP, UMAT;
DR   GO; GO:0005524; F:ATP binding; IDA:MGI.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0015232; F:heme transporter activity; TAS:Reactome.
DR   GO; GO:0015439; F:heme-transporting ATPase activity; IMP:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0070574; P:cadmium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0071585; P:detoxification of cadmium ion; IBA:RefGenome.
DR   GO; GO:0015886; P:heme transport; IDA:UniProtKB.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043588; P:skin development; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IDA:MGI.
//
ID   ABCB7_HUMAN             Reviewed;         752 AA.
AC   O75027; G3XAC4; O75345; Q5VWY7; Q5VWY8; Q9BRE1; Q9UND1; Q9UP01;
DE   RecName: Full=ATP-binding cassette sub-family B member 7, mitochondrial;
DE   AltName: Full=ATP-binding cassette transporter 7;
DE            Short=ABC transporter 7 protein;
DE   Flags: Precursor;
GN   Name=ABCB7; Synonyms=ABC7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0015232; F:heme transporter activity; TAS:ProtInc.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IBA:RefGenome.
DR   GO; GO:0015886; P:heme transport; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ABCB8_HUMAN             Reviewed;         735 AA.
AC   Q9NUT2; B2RBL8; O95787; Q53GM0;
DE   RecName: Full=ATP-binding cassette sub-family B member 8, mitochondrial;
DE   AltName: Full=Mitochondrial ATP-binding cassette 1;
DE            Short=M-ABC1;
DE   Flags: Precursor;
GN   Name=ABCB8; Synonyms=MABC1;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ABCB9_HUMAN             Reviewed;         766 AA.
AC   Q9NP78; B4E2J0; Q5W9G7; Q769F3; Q769F4; Q96AB1; Q9P208;
DE   RecName: Full=ATP-binding cassette sub-family B member 9;
DE   AltName: Full=ATP-binding cassette transporter 9;
DE            Short=ABC transporter 9 protein;
DE            Short=hABCB9;
DE   AltName: Full=TAP-like protein;
DE            Short=TAPL;
GN   Name=ABCB9; Synonyms=KIAA1520;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042288; F:MHC class I protein binding; IBA:RefGenome.
DR   GO; GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0015440; F:peptide-transporting ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0022891; F:substrate-specific transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0046978; F:TAP1 binding; IBA:RefGenome.
DR   GO; GO:0046979; F:TAP2 binding; IBA:RefGenome.
DR   GO; GO:0046980; F:tapasin binding; IBA:RefGenome.
DR   GO; GO:0035672; P:oligopeptide transmembrane transport; IBA:GOC.
DR   GO; GO:0015833; P:peptide transport; IDA:UniProtKB.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
//
ID   ABCBA_HUMAN             Reviewed;         738 AA.
AC   Q9NRK6; Q13040; Q6P1Q8; Q9H3V0;
DE   RecName: Full=ATP-binding cassette sub-family B member 10, mitochondrial;
DE   AltName: Full=ATP-binding cassette transporter 10;
DE            Short=ABC transporter 10 protein;
DE   AltName: Full=Mitochondrial ATP-binding cassette 2;
DE            Short=M-ABC2;
DE   Flags: Precursor;
GN   Name=ABCB10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0035672; P:oligopeptide transmembrane transport; IBA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   ABCBB_HUMAN             Reviewed;        1321 AA.
AC   O95342; Q53TL2; Q9UNB2;
DE   RecName: Full=Bile salt export pump;
DE   AltName: Full=ATP-binding cassette sub-family B member 11;
GN   Name=ABCB11; Synonyms=BSEP;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome.
DR   GO; GO:0015432; F:bile acid-exporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0015126; F:canalicular bile acid transmembrane transporter activity; IBA:RefGenome.
DR   GO; GO:0008554; F:sodium-exporting ATPase activity, phosphorylative mechanism; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0015722; P:canalicular bile acid transport; IBA:RefGenome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ABCC8_HUMAN             Reviewed;        1581 AA.
AC   Q09428; A6NMX8; E3UYX6; O75948; Q16583;
DE   RecName: Full=ATP-binding cassette sub-family C member 8;
DE   AltName: Full=Sulfonylurea receptor 1;
GN   Name=ABCC8; Synonyms=HRINS, SUR, SUR1;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0008281; F:sulfonylurea receptor activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCC9_HUMAN             Reviewed;        1549 AA.
AC   O60706; O60707;
DE   RecName: Full=ATP-binding cassette sub-family C member 9;
DE   AltName: Full=Sulfonylurea receptor 2;
GN   Name=ABCC9; Synonyms=SUR2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005267; F:potassium channel activity; IEA:Ensembl.
DR   GO; GO:0015459; F:potassium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0008281; F:sulfonylurea receptor activity; ISS:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IMP:MGI.
DR   GO; GO:0010107; P:potassium ion import; ISS:BHF-UCL.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; ISS:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCCB_HUMAN             Reviewed;        1382 AA.
AC   Q96J66; Q8TDJ0; Q96JA6; Q9BX80;
DE   RecName: Full=ATP-binding cassette sub-family C member 11;
DE   AltName: Full=Multidrug resistance-associated protein 8;
GN   Name=ABCC11; Synonyms=MRP8;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IDA:UniProt.
DR   GO; GO:0015216; F:purine nucleotide transmembrane transporter activity; IDA:UniProt.
DR   GO; GO:0015711; P:organic anion transport; IDA:UniProt.
DR   GO; GO:0015865; P:purine nucleotide transport; IDA:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCCD_HUMAN             Reviewed;         274 AA.
AC   Q9NSE7; Q8N6A4; Q8N6A5;
DE   RecName: Full=Putative ATP-binding cassette sub-family C member 13;
GN   Name=ABCC13; Synonyms=C21orf73, PRED6;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
//
ID   ABCD1_HUMAN             Reviewed;         745 AA.
AC   P33897; Q6GTZ2;
DE   RecName: Full=ATP-binding cassette sub-family D member 1;
DE   AltName: Full=Adrenoleukodystrophy protein;
DE            Short=ALDP;
GN   Name=ABCD1; Synonyms=ALD;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005325; F:peroxisomal fatty-acyl-CoA transporter activity; IGI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0043651; P:linoleic acid metabolic process; TAS:Reactome.
DR   GO; GO:0042758; P:long-chain fatty acid catabolic process; IGI:UniProtKB.
DR   GO; GO:0015910; P:peroxisomal long-chain fatty acid import; IGI:UniProtKB.
DR   GO; GO:0015919; P:peroxisomal membrane transport; NAS:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0042760; P:very long-chain fatty acid catabolic process; IDA:UniProtKB.
//
ID   ABCF3_HUMAN             Reviewed;         709 AA.
AC   Q9NUQ8; A8K241; Q86UA2; Q8NAN1; Q96GS8; Q9H7A8;
DE   RecName: Full=ATP-binding cassette sub-family F member 3;
GN   Name=ABCF3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
//
ID   ABCD4_HUMAN             Reviewed;         606 AA.
AC   O14678; A8K5L7; Q6IAQ0; Q96E75;
DE   RecName: Full=ATP-binding cassette sub-family D member 4;
DE   AltName: Full=PMP70-related protein;
DE            Short=P70R;
DE   AltName: Full=Peroxisomal membrane protein 1-like;
DE            Short=PXMP1-L;
DE   AltName: Full=Peroxisomal membrane protein 69;
DE            Short=PMP69;
GN   Name=ABCD4; Synonyms=PXMP1L;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; NAS:UniProtKB.
DR   GO; GO:0009235; P:cobalamin metabolic process; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; NAS:UniProtKB.
//
ID   ABCD2_HUMAN             Reviewed;         740 AA.
AC   Q9UBJ2; B2RAM3; Q13210; Q2M3H9;
DE   RecName: Full=ATP-binding cassette sub-family D member 2;
DE   AltName: Full=Adrenoleukodystrophy-like 1;
DE   AltName: Full=Adrenoleukodystrophy-related protein;
DE            Short=hALDR;
GN   Name=ABCD2; Synonyms=ALD1, ALDL1, ALDR, ALDRP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IGI:UniProtKB.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0042760; P:very long-chain fatty acid catabolic process; IGI:UniProtKB.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:UniProtKB.
//
ID   ABCD3_HUMAN             Reviewed;         659 AA.
AC   P28288; D3DT46; Q15271; Q6NUN5; Q96DA3; Q9H529;
DE   RecName: Full=ATP-binding cassette sub-family D member 3;
DE   AltName: Full=70 kDa peroxisomal membrane protein;
DE            Short=PMP70;
GN   Name=ABCD3; Synonyms=PMP70, PXMP1;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IGI:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0042760; P:very long-chain fatty acid catabolic process; IGI:UniProtKB.
//
ID   ABCF1_HUMAN             Reviewed;         845 AA.
AC   Q8NE71; A2BF75; O14897; Q69YP6;
DE   RecName: Full=ATP-binding cassette sub-family F member 1;
DE   AltName: Full=ATP-binding cassette 50;
DE   AltName: Full=TNF-alpha-stimulated ABC protein;
GN   Name=ABCF1; Synonyms=ABC50;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0008494; F:translation activator activity; IDA:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0006413; P:translational initiation; IMP:UniProtKB.
//
ID   ABCE1_HUMAN             Reviewed;         599 AA.
AC   P61221; O88793; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66;
DE   RecName: Full=ATP-binding cassette sub-family E member 1;
DE   AltName: Full=2'-5'-oligoadenylate-binding protein;
DE   AltName: Full=HuHP68;
DE   AltName: Full=RNase L inhibitor;
DE   AltName: Full=Ribonuclease 4 inhibitor;
DE            Short=RNS4I;
GN   Name=ABCE1; Synonyms=RLI, RNASEL1, RNASELI, RNS4I;
GN   ORFNames=OK/SW-cl.40;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008428; F:ribonuclease inhibitor activity; TAS:ProtInc.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ABCF2_HUMAN             Reviewed;         623 AA.
AC   Q9UG63; O60864; Q75MJ0; Q75MJ1; Q96TE8;
DE   RecName: Full=ATP-binding cassette sub-family F member 2;
DE   AltName: Full=Iron-inhibited ABC transporter 2;
GN   Name=ABCF2; ORFNames=HUSSY-18;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ABCG1_HUMAN             Reviewed;         678 AA.
AC   P45844; Q86SU8; Q96L76; Q9BXK6; Q9BXK7; Q9BXK8; Q9BXK9; Q9BXL0;
AC   Q9BXL1; Q9BXL2; Q9BXL3; Q9BXL4;
DE   RecName: Full=ATP-binding cassette sub-family G member 1;
DE   AltName: Full=ATP-binding cassette transporter 8;
DE   AltName: Full=White protein homolog;
GN   Name=ABCG1; Synonyms=ABC8, WHT1;
DR   GO; GO:0043531; F:ADP binding; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0015485; F:cholesterol binding; IC:BHF-UCL.
DR   GO; GO:0017127; F:cholesterol transporter activity; IDA:BHF-UCL.
DR   GO; GO:0034437; F:glycoprotein transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IC:BHF-UCL.
DR   GO; GO:0005548; F:phospholipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; NAS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0034041; F:sterol-transporting ATPase activity; IDA:BHF-UCL.
DR   GO; GO:0019534; F:toxin transporter activity; IDA:BHF-UCL.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0009720; P:detection of hormone stimulus; NAS:UniProtKB.
DR   GO; GO:0034436; P:glycoprotein transport; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; ISS:BHF-UCL.
DR   GO; GO:0032367; P:intracellular cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; ISS:BHF-UCL.
DR   GO; GO:0010887; P:negative regulation of cholesterol storage; TAS:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IMP:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; IMP:BHF-UCL.
DR   GO; GO:0045542; P:positive regulation of cholesterol biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IEA:Ensembl.
DR   GO; GO:0010872; P:regulation of cholesterol esterification; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0055099; P:response to high density lipoprotein particle; IEA:Ensembl.
DR   GO; GO:0033993; P:response to lipid; IDA:BHF-UCL.
DR   GO; GO:0010033; P:response to organic substance; IDA:UniProtKB.
DR   GO; GO:0043691; P:reverse cholesterol transport; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:1901998; P:toxin transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCG2_HUMAN             Reviewed;         655 AA.
AC   Q9UNQ0; A0A1W3; A8K1T5; O95374; Q4W5I3; Q53ZQ1; Q569L4; Q5YLG4;
AC   Q86V64; Q8IX16; Q96LD6; Q96TA8; Q9BY73; Q9NUS0;
DE   RecName: Full=ATP-binding cassette sub-family G member 2;
DE   AltName: Full=Breast cancer resistance protein;
DE   AltName: Full=CDw338;
DE   AltName: Full=Mitoxantrone resistance-associated protein;
DE   AltName: Full=Placenta-specific ATP-binding cassette transporter;
DE   AltName: Full=Urate exporter;
DE   AltName: CD_antigen=CD338;
GN   Name=ABCG2; Synonyms=ABCP, BCRP, BCRP1, MXR;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0015232; F:heme transporter activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008559; F:xenobiotic-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0006855; P:drug transmembrane transport; TAS:Reactome.
DR   GO; GO:0015886; P:heme transport; TAS:GOC.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0046415; P:urate metabolic process; IMP:UniProtKB.
DR   GO; GO:0042908; P:xenobiotic transport; TAS:GOC.
//
ID   ABCG4_HUMAN             Reviewed;         646 AA.
AC   Q9H172; A8K1B5; Q8WWH0; Q8WWH1; Q8WWH2;
DE   RecName: Full=ATP-binding cassette sub-family G member 4;
GN   Name=ABCG4; Synonyms=WHITE2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0017127; F:cholesterol transporter activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; TAS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCG5_HUMAN             Reviewed;         651 AA.
AC   Q9H222; Q96QZ2; Q96QZ3;
DE   RecName: Full=ATP-binding cassette sub-family G member 5;
DE   AltName: Full=Sterolin-1;
GN   Name=ABCG5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0017127; F:cholesterol transporter activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0033344; P:cholesterol efflux; IGI:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007588; P:excretion; IGI:BHF-UCL.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; IC:BHF-UCL.
DR   GO; GO:0045796; P:negative regulation of intestinal cholesterol absorption; IMP:BHF-UCL.
DR   GO; GO:0010949; P:negative regulation of intestinal phytosterol absorption; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0015918; P:sterol transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABCG8_HUMAN             Reviewed;         673 AA.
AC   Q9H221; Q53QN8;
DE   RecName: Full=ATP-binding cassette sub-family G member 8;
DE   AltName: Full=Sterolin-2;
GN   Name=ABCG8;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0015248; F:sterol transporter activity; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0033344; P:cholesterol efflux; IGI:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007588; P:excretion; IGI:BHF-UCL.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; IC:BHF-UCL.
DR   GO; GO:0045796; P:negative regulation of intestinal cholesterol absorption; IMP:BHF-UCL.
DR   GO; GO:0010949; P:negative regulation of intestinal phytosterol absorption; IMP:BHF-UCL.
DR   GO; GO:0015914; P:phospholipid transport; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0015918; P:sterol transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ABD12_HUMAN             Reviewed;         398 AA.
AC   Q8N2K0; A6NED4; A6NJ90; A8K450; B4DE71; Q5T710; Q5T711; Q96CR1;
AC   Q9BX05; Q9NPX7; Q9UFV6;
DE   RecName: Full=Monoacylglycerol lipase ABHD12;
DE            EC=3.1.1.23;
DE   AltName: Full=2-arachidonoylglycerol hydrolase;
DE   AltName: Full=Abhydrolase domain-containing protein 12;
GN   Name=ABHD12; Synonyms=C20orf22;
DR   GO; GO:0047372; F:acylglycerol lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0006660; P:phosphatidylserine catabolic process; IEA:Ensembl.
DR   GO; GO:0010996; P:response to auditory stimulus; IEA:Ensembl.
//
ID   ABEC1_HUMAN             Reviewed;         236 AA.
AC   P41238; Q9UE64; Q9UM71;
DE   RecName: Full=C->U-editing enzyme APOBEC-1;
DE            EC=3.5.4.-;
DE   AltName: Full=Apolipoprotein B mRNA-editing enzyme 1;
DE   AltName: Full=HEPR;
GN   Name=APOBEC1;
DR   GO; GO:0017091; F:AU-rich element binding; IEA:Ensembl.
DR   GO; GO:0004126; F:cytidine deaminase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0009972; P:cytidine deamination; TAS:GOC.
DR   GO; GO:0016554; P:cytidine to uridine editing; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0080111; P:DNA demethylation; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0016556; P:mRNA modification; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048255; P:mRNA stabilization; IEA:Ensembl.
DR   GO; GO:0090310; P:negative regulation of methylation-dependent chromatin silencing; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   ABEC2_HUMAN             Reviewed;         224 AA.
AC   Q9Y235; B2R899; Q53F28; Q5TGU5; Q5TGU6;
DE   RecName: Full=Probable C->U-editing enzyme APOBEC-2;
DE            EC=3.5.4.-;
GN   Name=APOBEC2;
DR   GO; GO:0004126; F:cytidine deaminase activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009972; P:cytidine deamination; TAS:GOC.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0016556; P:mRNA modification; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   ABEC4_HUMAN             Reviewed;         367 AA.
AC   Q8WW27; Q8N7F6;
DE   RecName: Full=Putative C->U-editing enzyme APOBEC-4;
DE            EC=3.5.4.-;
DE   AltName: Full=Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4;
GN   Name=APOBEC4; Synonyms=C1orf169;
DR   GO; GO:0016814; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   ABH15_HUMAN             Reviewed;         468 AA.
AC   Q6UXT9; Q96EC5;
DE   RecName: Full=Abhydrolase domain-containing protein 15;
DE            EC=3.1.1.-;
DE   Flags: Precursor;
GN   Name=ABHD15; ORFNames=UNQ6510/PRO21435;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHD1_HUMAN             Reviewed;         405 AA.
AC   Q96SE0; B3KSF6; E9PDR9; Q05BY3; Q53SZ1; Q8IXQ7;
DE   RecName: Full=Abhydrolase domain-containing protein 1;
DE            EC=3.1.1.-;
DE   AltName: Full=Lung alpha/beta hydrolase 1;
GN   Name=ABHD1; Synonyms=LABH1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHD3_HUMAN             Reviewed;         409 AA.
AC   Q8WU67; B0YIV0; O43411;
DE   RecName: Full=Abhydrolase domain-containing protein 3;
DE            EC=3.1.1.-;
DE   AltName: Full=Lung alpha/beta hydrolase 3;
GN   Name=ABHD3; Synonyms=LABH3;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHD2_HUMAN             Reviewed;         425 AA.
AC   P08910; Q53G48; Q53GU0; Q5FVD9; Q8TC79;
DE   RecName: Full=Abhydrolase domain-containing protein 2;
DE            EC=3.1.1.-;
DE   AltName: Full=Lung alpha/beta hydrolase 2;
DE   AltName: Full=Protein PHPS1-2;
GN   Name=ABHD2; Synonyms=LABH2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
//
ID   ABHD4_HUMAN             Reviewed;         342 AA.
AC   Q8TB40; Q9H9E0;
DE   RecName: Full=Abhydrolase domain-containing protein 4;
DE            EC=3.1.1.-;
DE   AltName: Full=Alpha/beta-hydrolase 4;
DE   AltName: Full=Lyso-N-acylphosphatidylethanolamine lipase;
GN   Name=ABHD4;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   ABHD5_HUMAN             Reviewed;         349 AA.
AC   Q8WTS1; B2R9K0; Q9Y369;
DE   RecName: Full=1-acylglycerol-3-phosphate O-acyltransferase ABHD5;
DE            EC=2.3.1.51;
DE   AltName: Full=Abhydrolase domain-containing protein 5;
DE   AltName: Full=Lipid droplet-binding protein CGI-58;
GN   Name=ABHD5; Synonyms=NCIE2; ORFNames=CGI-58;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042171; F:lysophosphatidic acid acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0010891; P:negative regulation of sequestering of triglyceride; IDA:UniProtKB.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IEA:Ensembl.
DR   GO; GO:0010898; P:positive regulation of triglyceride catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   ABHD6_HUMAN             Reviewed;         337 AA.
AC   Q9BV23; B2R7Y9; Q6ZMF7;
DE   RecName: Full=Monoacylglycerol lipase ABHD6;
DE            EC=3.1.1.23;
DE   AltName: Full=2-arachidonoylglycerol hydrolase;
DE   AltName: Full=Abhydrolase domain-containing protein 6;
GN   Name=ABHD6;
DR   GO; GO:0047372; F:acylglycerol lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:2000124; P:regulation of endocannabinoid signaling pathway; IEA:Ensembl.
//
ID   ABHD8_HUMAN             Reviewed;         439 AA.
AC   Q96I13; Q9HAE9;
DE   RecName: Full=Abhydrolase domain-containing protein 8;
DE            EC=3.-.-.-;
GN   Name=ABHD8;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHDA_HUMAN             Reviewed;         306 AA.
AC   Q9NUJ1; D3DN63; Q8TCF9;
DE   RecName: Full=Mycophenolic acid acyl-glucuronide esterase, mitochondrial;
DE            EC=3.1.1.93;
DE   AltName: Full=Alpha/beta hydrolase domain-containing protein 10;
DE            Short=Abhydrolase domain-containing protein 10;
DE   Flags: Precursor;
GN   Name=ABHD10;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IDA:BHF-UCL.
DR   GO; GO:0019391; P:glucuronoside catabolic process; IDA:BHF-UCL.
//
ID   ABHDB_HUMAN             Reviewed;         315 AA.
AC   Q8NFV4; H7BYM8; Q6PJU0; Q8N722; Q8N723; Q8NFV2; Q8NFV3; Q9HBS8;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 11;
DE            Short=Abhydrolase domain-containing protein 11;
DE            EC=3.-.-.-;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 21 protein;
GN   Name=ABHD11; Synonyms=WBSCR21; ORFNames=PP1226;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHDD_HUMAN             Reviewed;         337 AA.
AC   Q7L211; B3KWE7; Q8NBW1; Q96JX9;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 13;
DE            Short=Abhydrolase domain-containing protein 13;
DE            EC=3.-.-.-;
GN   Name=ABHD13; Synonyms=C13orf6;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHEA_HUMAN             Reviewed;         271 AA.
AC   Q9BUJ0; Q6UXU8; Q9Y3T7;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 14A;
DE            Short=Abhydrolase domain-containing protein 14A;
DE            EC=3.-.-.-;
GN   Name=ABHD14A; ORFNames=UNQ1913/PRO4373;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHEB_HUMAN             Reviewed;         210 AA.
AC   Q96IU4; Q86VK8; Q8N8W5;
DE   RecName: Full=Alpha/beta hydrolase domain-containing protein 14B;
DE            Short=Abhydrolase domain-containing protein 14B;
DE            EC=3.-.-.-;
DE   AltName: Full=CCG1-interacting factor B;
GN   Name=ABHD14B; Synonyms=CIB;
DR   GO; GO:0016787; F:hydrolase activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProt.
//
ID   ABHGA_HUMAN             Reviewed;         558 AA.
AC   O95870; A2BEY3; B7Z4R6; Q5SRR1; Q5SRR2; Q8WYH0; Q9NW33;
DE   RecName: Full=Abhydrolase domain-containing protein 16A;
DE            EC=3.-.-.-;
DE   AltName: Full=HLA-B-associated transcript 5;
DE   AltName: Full=Protein G5;
GN   Name=ABHD16A; Synonyms=BAT5, G5, NG26; ORFNames=PP199;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABHGB_HUMAN             Reviewed;         469 AA.
AC   Q9H3Z7;
DE   RecName: Full=Abhydrolase domain-containing protein 16B;
DE            EC=3.-.-.-;
GN   Name=ABHD16B; Synonyms=C20orf135;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ABI1_HUMAN              Reviewed;         508 AA.
AC   Q8IZP0; A9Z1Y6; B3KX62; B4DQ58; H7BXI6; O15147; O76049; O95060;
AC   Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8TB63;
AC   Q96S81; Q9NXZ9; Q9NYB8;
DE   RecName: Full=Abl interactor 1;
DE   AltName: Full=Abelson interactor 1;
DE            Short=Abi-1;
DE   AltName: Full=Abl-binding protein 4;
DE            Short=AblBP4;
DE   AltName: Full=Eps8 SH3 domain-binding protein;
DE            Short=Eps8-binding protein;
DE   AltName: Full=Nap1-binding protein;
DE            Short=Nap1BP;
DE   AltName: Full=Spectrin SH3 domain-binding protein 1;
DE   AltName: Full=e3B1;
GN   Name=ABI1; Synonyms=SSH3BP1;
DR   GO; GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IEA:Ensembl.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; IDA:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0072673; P:lamellipodium morphogenesis; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   ABI2_HUMAN              Reviewed;         513 AA.
AC   Q9NYB9; B4DSN1; Q13147; Q13249; Q13801; Q9BV70;
DE   RecName: Full=Abl interactor 2;
DE   AltName: Full=Abelson interactor 2;
DE            Short=Abi-2;
DE   AltName: Full=Abl-binding protein 3;
DE            Short=AblBP3;
DE   AltName: Full=Arg-binding protein 1;
DE            Short=ArgBP1;
GN   Name=ABI2; Synonyms=ARGBPIA;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019900; F:kinase binding; NAS:UniProtKB.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IDA:UniProt.
DR   GO; GO:0016601; P:Rac protein signal transduction; IDA:UniProt.
//
ID   ABI3_HUMAN              Reviewed;         366 AA.
AC   Q9P2A4; C9IZN8; Q9H0P6;
DE   RecName: Full=ABI gene family member 3;
DE   AltName: Full=New molecule including SH3;
DE            Short=Nesh;
GN   Name=ABI3; Synonyms=NESH;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:MGI.
//
ID   ABL1_HUMAN              Reviewed;        1130 AA.
AC   P00519; A3KFJ3; Q13869; Q13870; Q16133; Q17R61; Q45F09;
DE   RecName: Full=Tyrosine-protein kinase ABL1;
DE            EC=2.7.10.2;
DE   AltName: Full=Abelson murine leukemia viral oncogene homolog 1;
DE   AltName: Full=Abelson tyrosine-protein kinase 1;
DE   AltName: Full=Proto-oncogene c-Abl;
DE   AltName: Full=p150;
GN   Name=ABL1; Synonyms=ABL, JTK7;
DR   GuidetoPHARMACOLOGY; 1923; -.
DR   GO; GO:0003785; F:actin monomer binding; TAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0070064; F:proline-rich region binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; TAS:UniProtKB.
DR   GO; GO:0006298; P:mismatch repair; TAS:ProtInc.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:2000145; P:regulation of cell motility; TAS:UniProtKB.
DR   GO; GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.
DR   GO; GO:2001020; P:regulation of response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IDA:UniProtKB.
//
ID   ABL2_HUMAN              Reviewed;        1182 AA.
AC   P42684; A0M8X0; B7UEF2; B7UEF3; B7UEF4; B7UEF5; Q5T0X6; Q5W0C5;
AC   Q6NZY6; Q7Z301;
DE   RecName: Full=Abelson tyrosine-protein kinase 2;
DE            EC=2.7.10.2;
DE   AltName: Full=Abelson murine leukemia viral oncogene homolog 2;
DE   AltName: Full=Abelson-related gene protein;
DE   AltName: Full=Tyrosine-protein kinase ARG;
GN   Name=ABL2; Synonyms=ABLL, ARG;
DR   GuidetoPHARMACOLOGY; 1924; -.
DR   GO; GO:0051015; F:actin filament binding; TAS:UniProtKB.
DR   GO; GO:0003785; F:actin monomer binding; TAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; TAS:UniProtKB.
DR   GO; GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ABLM1_HUMAN             Reviewed;         778 AA.
AC   O14639; A6NI16; A6NJ06; A8MXA9; Q15039; Q5JVV1; Q5JVV2; Q5T6N3;
AC   Q5T6N5; Q68CQ9; Q9BUP1;
DE   RecName: Full=Actin-binding LIM protein 1;
DE            Short=abLIM-1;
DE   AltName: Full=Actin-binding LIM protein family member 1;
DE   AltName: Full=Actin-binding double zinc finger protein;
DE   AltName: Full=LIMAB1;
DE   AltName: Full=Limatin;
GN   Name=ABLIM1; Synonyms=ABLIM, KIAA0059, LIMAB1;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   ABLM2_HUMAN             Reviewed;         611 AA.
AC   Q6H8Q1; E9PF39; Q08E71; Q19VH0; Q6H8Q0; Q6NX73; Q8N3C5; Q8N9E9;
AC   Q8N9G2; Q96JL7;
DE   RecName: Full=Actin-binding LIM protein 2;
DE            Short=abLIM-2;
DE   AltName: Full=Actin-binding LIM protein family member 2;
GN   Name=ABLIM2; Synonyms=KIAA1808;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   ABLM3_HUMAN             Reviewed;         683 AA.
AC   O94929; A8K121; Q19VH3; Q658S1; Q68CI5; Q9BV32;
DE   RecName: Full=Actin-binding LIM protein 3;
DE            Short=abLIM-3;
DE   AltName: Full=Actin-binding LIM protein family member 3;
GN   Name=ABLIM3; Synonyms=KIAA0843; ORFNames=HMFN1661;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   ABRAL_HUMAN             Reviewed;          81 AA.
AC   Q9P1F3; Q5SZC8; Q9P0A1;
DE   RecName: Full=Costars family protein ABRACL;
DE   AltName: Full=ABRA C-terminal-like protein;
GN   Name=ABRACL; Synonyms=C6orf115; ORFNames=HSPC280, PRO2013;
//
ID   ABRA_HUMAN              Reviewed;         381 AA.
AC   Q8N0Z2;
DE   RecName: Full=Actin-binding Rho-activating protein;
DE   AltName: Full=Striated muscle activator of Rho-dependent signaling;
DE            Short=STARS;
GN   Name=ABRA;
DR   GO; GO:0003779; F:actin binding; ISS:HGNC.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; ISS:HGNC.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:HGNC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ABR_HUMAN               Reviewed;         859 AA.
AC   Q12979; B3KW89; B7Z6H7; D3DTH3; D3DTH4; F5H3S2; F5H8B3; Q13693;
AC   Q13694;
DE   RecName: Full=Active breakpoint cluster region-related protein;
GN   Name=ABR;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043314; P:negative regulation of neutrophil degranulation; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ABT1_HUMAN              Reviewed;         272 AA.
AC   Q9ULW3;
DE   RecName: Full=Activator of basal transcription 1;
DE            Short=hABT1;
DE   AltName: Full=Basal transcriptional activator;
GN   Name=ABT1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ABTB1_HUMAN             Reviewed;         478 AA.
AC   Q969K4; D3DNB0; Q6ZNU9; Q71MF1; Q96S62; Q96S63;
DE   RecName: Full=Ankyrin repeat and BTB/POZ domain-containing protein 1;
DE   AltName: Full=Elongation factor 1A-binding protein;
GN   Name=ABTB1; Synonyms=BPOZ; ORFNames=PP2259;
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
//
ID   ABTB2_HUMAN             Reviewed;        1025 AA.
AC   Q8N961; A8K6S9; E9PRW7; Q52LD6; Q6MZW4; Q8NB44;
DE   RecName: Full=Ankyrin repeat and BTB/POZ domain-containing protein 2;
GN   Name=ABTB2;
//
ID   ACACA_HUMAN             Reviewed;        2346 AA.
AC   Q13085; B2RP68; Q6KEV6; Q6XDA8; Q7Z2G8; Q7Z561; Q7Z563; Q7Z564;
AC   Q86WB2; Q86WB3;
DE   RecName: Full=Acetyl-CoA carboxylase 1;
DE            Short=ACC1;
DE            EC=6.4.1.2;
DE   AltName: Full=ACC-alpha;
DE   Includes:
DE     RecName: Full=Biotin carboxylase;
DE              EC=6.3.4.14;
GN   Name=ACACA; Synonyms=ACAC, ACC1, ACCA;
DR   GuidetoPHARMACOLOGY; 1263; -.
DR   GO; GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004075; F:biotin carboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0055088; P:lipid homeostasis; IEA:Ensembl.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:2001295; P:malonyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044268; P:multicellular organismal protein metabolic process; IEA:Ensembl.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   ACACB_HUMAN             Reviewed;        2458 AA.
AC   O00763; A6NK36; Q16852; Q1HEC1; Q6KE87; Q6KE89; Q6TY48;
DE   RecName: Full=Acetyl-CoA carboxylase 2;
DE            EC=6.4.1.2;
DE   AltName: Full=ACC-beta;
DE   Includes:
DE     RecName: Full=Biotin carboxylase;
DE              EC=6.3.4.14;
GN   Name=ACACB; Synonyms=ACC2, ACCB;
DR   GuidetoPHARMACOLOGY; 1264; -.
DR   GO; GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0009374; F:biotin binding; IEA:Ensembl.
DR   GO; GO:0004075; F:biotin carboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:2001295; P:malonyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   ACAD8_HUMAN             Reviewed;         415 AA.
AC   Q9UKU7; Q9BUS8;
DE   RecName: Full=Isobutyryl-CoA dehydrogenase, mitochondrial;
DE            EC=1.3.99.-;
DE   AltName: Full=Activator-recruited cofactor 42 kDa component;
DE            Short=ARC42;
DE   AltName: Full=Acyl-CoA dehydrogenase family member 8;
DE            Short=ACAD-8;
DE   Flags: Precursor;
GN   Name=ACAD8; Synonyms=ARC42, IBD;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; EXP:Reactome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006574; P:valine catabolic process; IEA:UniProtKB-UniPathway.
//
ID   ACAD9_HUMAN             Reviewed;         621 AA.
AC   Q9H845; D3DNB8; Q8WXX3;
DE   RecName: Full=Acyl-CoA dehydrogenase family member 9, mitochondrial;
DE            Short=ACAD-9;
DE            EC=1.3.99.-;
DE   Flags: Precursor;
GN   Name=ACAD9;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
//
ID   ACADL_HUMAN             Reviewed;         430 AA.
AC   P28330; B2R8T3; Q8IUN8;
DE   RecName: Full=Long-chain specific acyl-CoA dehydrogenase, mitochondrial;
DE            Short=LCAD;
DE            EC=1.3.8.8;
DE   Flags: Precursor;
GN   Name=ACADL;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:Ensembl.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0004466; F:long-chain-acyl-CoA dehydrogenase activity; ISS:BHF-UCL.
DR   GO; GO:0016401; F:palmitoyl-CoA oxidase activity; ISS:BHF-UCL.
DR   GO; GO:0042413; P:carnitine catabolic process; ISS:BHF-UCL.
DR   GO; GO:0019254; P:carnitine metabolic process, CoA-linked; ISS:BHF-UCL.
DR   GO; GO:0044242; P:cellular lipid catabolic process; ISS:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; ISS:BHF-UCL.
DR   GO; GO:0042758; P:long-chain fatty acid catabolic process; IEA:Ensembl.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0046322; P:negative regulation of fatty acid oxidation; ISS:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:BHF-UCL.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0090181; P:regulation of cholesterol metabolic process; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0001659; P:temperature homeostasis; ISS:BHF-UCL.
//
ID   ACADM_HUMAN             Reviewed;         421 AA.
AC   P11310; Q5T4U4; Q9NYF1;
DE   RecName: Full=Medium-chain specific acyl-CoA dehydrogenase, mitochondrial;
DE            Short=MCAD;
DE            EC=1.3.8.7;
DE   Flags: Precursor;
GN   Name=ACADM;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IMP:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IDA:BHF-UCL.
DR   GO; GO:0070991; F:medium-chain-acyl-CoA dehydrogenase activity; IDA:BHF-UCL.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0045329; P:carnitine biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0019254; P:carnitine metabolic process, CoA-linked; IMP:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IMP:UniProtKB.
DR   GO; GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IDA:BHF-UCL.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0051793; P:medium-chain fatty acid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051791; P:medium-chain fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ACADS_HUMAN             Reviewed;         412 AA.
AC   P16219; P78331;
DE   RecName: Full=Short-chain specific acyl-CoA dehydrogenase, mitochondrial;
DE            Short=SCAD;
DE            EC=1.3.8.1;
DE   AltName: Full=Butyryl-CoA dehydrogenase;
DE   Flags: Precursor;
GN   Name=ACADS;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0004085; F:butyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:Ensembl.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046359; P:butyrate catabolic process; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ACADV_HUMAN             Reviewed;         655 AA.
AC   P49748; B4DEB6; F5H2A9; O76056; Q8WUL0;
DE   RecName: Full=Very long-chain specific acyl-CoA dehydrogenase, mitochondrial;
DE            Short=VLCAD;
DE            EC=1.3.8.9;
DE   Flags: Precursor;
GN   Name=ACADVL; Synonyms=VLCAD;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004466; F:long-chain-acyl-CoA dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0015980; P:energy derivation by oxidation of organic compounds; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; ISS:BHF-UCL.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0046322; P:negative regulation of fatty acid oxidation; ISS:BHF-UCL.
DR   GO; GO:0090181; P:regulation of cholesterol metabolic process; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0001659; P:temperature homeostasis; ISS:BHF-UCL.
//
ID   ACAP1_HUMAN             Reviewed;         740 AA.
AC   Q15027; Q53XN9;
DE   RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1;
DE   AltName: Full=Centaurin-beta-1;
DE            Short=Cnt-b1;
GN   Name=ACAP1; Synonyms=CENTB1, KIAA0050;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   ACAP2_HUMAN             Reviewed;         778 AA.
AC   Q15057; A8K2V4; Q8N5Z8; Q9UQR3;
DE   RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2;
DE   AltName: Full=Centaurin-beta-2;
DE            Short=Cnt-b2;
GN   Name=ACAP2; Synonyms=CENTB2, KIAA0041;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0036010; P:protein localization to endosome; ISS:UniProtKB.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   ACAP3_HUMAN             Reviewed;         834 AA.
AC   Q96P50; B1AMF5; Q5TA42; Q5TA43; Q86UT3; Q9BSR9; Q9C0E7;
DE   RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3;
DE   AltName: Full=Centaurin-beta-5;
DE            Short=Cnt-b5;
GN   Name=ACAP3; Synonyms=CENTB5, KIAA1716;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   ACATN_HUMAN             Reviewed;         549 AA.
AC   O00400; B2R5Q2; D3DNK4;
DE   RecName: Full=Acetyl-coenzyme A transporter 1;
DE            Short=AT-1;
DE            Short=Acetyl-CoA transporter 1;
DE   AltName: Full=Solute carrier family 33 member 1;
GN   Name=SLC33A1; Synonyms=ACATN, AT1;
DR   GuidetoPHARMACOLOGY; 1134; -.
DR   GO; GO:0008521; F:acetyl-CoA transporter activity; TAS:ProtInc.
DR   GO; GO:0015876; P:acetyl-CoA transport; TAS:GOC.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACBD4_HUMAN             Reviewed;         268 AA.
AC   Q8NC06; D3DX64; Q8IUT1; Q9H8Q4;
DE   RecName: Full=Acyl-CoA-binding domain-containing protein 4;
GN   Name=ACBD4; ORFNames=HMFT0700;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
//
ID   ACBD5_HUMAN             Reviewed;         534 AA.
AC   Q5T8D3; B3KQ56; D3DRW0; Q5T8D4; Q5T8E1; Q5T8E2; Q86UV1; Q8N6E3;
AC   Q9UFB5;
DE   RecName: Full=Acyl-CoA-binding domain-containing protein 5;
GN   Name=ACBD5; Synonyms=KIAA1996;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   ACBD7_HUMAN             Reviewed;          88 AA.
AC   Q8N6N7; A6NCI2; B3KTG8;
DE   RecName: Full=Acyl-CoA-binding domain-containing protein 7;
GN   Name=ACBD7;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
//
ID   ACBD6_HUMAN             Reviewed;         282 AA.
AC   Q9BR61;
DE   RecName: Full=Acyl-CoA-binding domain-containing protein 6;
GN   Name=ACBD6;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
//
ID   ACBG1_HUMAN             Reviewed;         724 AA.
AC   Q96GR2; B2RB61; O75126; Q76N27; Q9HC26;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG1;
DE            EC=6.2.1.3;
DE   AltName: Full=Acyl-CoA synthetase bubblegum family member 1;
DE            Short=hBG1;
DE            Short=hsBG;
DE            Short=hsBGM;
DE   AltName: Full=Lipidosin;
GN   Name=ACSBG1; Synonyms=BGM, KIAA0631, LPD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:HGNC.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:HGNC.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:HGNC.
DR   GO; GO:0042552; P:myelination; NAS:HGNC.
DR   GO; GO:0001552; P:ovarian follicle atresia; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:HGNC.
//
ID   ACBG2_HUMAN             Reviewed;         666 AA.
AC   Q5FVE4; B3KSF2; Q6UWJ3; Q7Z5A0; Q8WW03; Q96M36; Q9BYZ3; Q9H0C4;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2;
DE            EC=6.2.1.3;
DE   AltName: Full=Acyl-CoA synthetase bubblegum family member 2;
DE   AltName: Full=Bubblegum-related protein;
DE   AltName: Full=PRTD-NY3;
GN   Name=ACSBG2; Synonyms=BGR; ORFNames=UNQ2443/PRO5005;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IDA:MGI.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:MGI.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:MGI.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:GOC.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   ACBP_HUMAN              Reviewed;          87 AA.
AC   P07108; B8ZWD2; B8ZWD6; B8ZWD7; P08869; Q4VWZ6; Q53SQ7; Q6IB48;
AC   Q9UCI8;
DE   RecName: Full=Acyl-CoA-binding protein;
DE            Short=ACBP;
DE   AltName: Full=Diazepam-binding inhibitor;
DE            Short=DBI;
DE   AltName: Full=Endozepine;
DE            Short=EP;
GN   Name=DBI;
DR   GO; GO:0030156; F:benzodiazepine receptor binding; TAS:ProtInc.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   ACD10_HUMAN             Reviewed;        1059 AA.
AC   Q6JQN1; G3XAJ0; Q8N828; Q8NAP2; Q96BX5;
DE   RecName: Full=Acyl-CoA dehydrogenase family member 10;
DE            Short=ACAD-10;
DE            EC=1.3.99.-;
GN   Name=ACAD10;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
//
ID   ACD11_HUMAN             Reviewed;         780 AA.
AC   Q709F0; Q08AF0; Q658N9; Q658Y2; Q6ZND2; Q8WUT6; Q9H9R3;
DE   RecName: Full=Acyl-CoA dehydrogenase family member 11;
DE            Short=ACAD-11;
DE            EC=1.3.99.-;
GN   Name=ACAD11;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004466; F:long-chain-acyl-CoA dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0070991; F:medium-chain-acyl-CoA dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0017099; F:very-long-chain-acyl-CoA dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IDA:UniProtKB.
//
ID   ACDSB_HUMAN             Reviewed;         432 AA.
AC   P45954; Q5SQN6; Q96CX7;
DE   RecName: Full=Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial;
DE            Short=SBCAD;
DE            EC=1.3.8.5;
DE   AltName: Full=2-methyl branched chain acyl-CoA dehydrogenase;
DE            Short=2-MEBCAD;
DE   AltName: Full=2-methylbutyryl-coenzyme A dehydrogenase;
DE            Short=2-methylbutyryl-CoA dehydrogenase;
DE   Flags: Precursor;
GN   Name=ACADSB;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; EXP:Reactome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ACD_HUMAN               Reviewed;         544 AA.
AC   Q96AP0; Q562H5; Q9H8F9;
DE   RecName: Full=Adrenocortical dysplasia protein homolog;
DE   AltName: Full=POT1 and TIN2-interacting protein;
GN   Name=ACD; Synonyms=PIP1, PTOP, TINT1, TPP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0070182; F:DNA polymerase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:BHF-UCL.
DR   GO; GO:0032211; P:negative regulation of telomere maintenance via telomerase; IMP:BHF-UCL.
DR   GO; GO:0060381; P:positive regulation of single-stranded telomeric DNA binding; IDA:BHF-UCL.
DR   GO; GO:0051973; P:positive regulation of telomerase activity; IDA:BHF-UCL.
DR   GO; GO:0031848; P:protection from non-homologous end joining at telomere; ISS:BHF-UCL.
DR   GO; GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.
DR   GO; GO:0035282; P:segmentation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0032202; P:telomere assembly; IMP:BHF-UCL.
DR   GO; GO:0016233; P:telomere capping; IGI:BHF-UCL.
DR   GO; GO:0000723; P:telomere maintenance; IDA:MGI.
DR   GO; GO:0001655; P:urogenital system development; IEA:Ensembl.
//
ID   ACE2_HUMAN              Reviewed;         805 AA.
AC   Q9BYF1; C7ECU1; Q6UWP0; Q86WT0; Q9NRA7; Q9UFZ6;
DE   RecName: Full=Angiotensin-converting enzyme 2;
DE            EC=3.4.17.23;
DE   AltName: Full=ACE-related carboxypeptidase;
DE   AltName: Full=Angiotensin-converting enzyme homolog;
DE            Short=ACEH;
DE   AltName: Full=Metalloprotease MPROT15;
DE   Contains:
DE     RecName: Full=Processed angiotensin-converting enzyme 2;
DE   Flags: Precursor;
GN   Name=ACE2; ORFNames=UNQ868/PRO1885;
DR   GuidetoPHARMACOLOGY; 1614; -.
DR   GO; GO:0004180; F:carboxypeptidase activity; IDA:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:BHF-UCL.
DR   GO; GO:0002005; P:angiotensin catabolic process in blood; IC:BHF-UCL.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0003051; P:angiotensin-mediated drinking behavior; IMP:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IC:BHF-UCL.
DR   GO; GO:0032800; P:receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0046813; P:receptor-mediated virion attachment to host cell; IDA:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0001817; P:regulation of cytokine production; IC:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IMP:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IC:BHF-UCL.
DR   GO; GO:0042312; P:regulation of vasodilation; IC:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IDA:GOC.
DR   GO; GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
//
ID   ACER1_HUMAN             Reviewed;         264 AA.
AC   Q8TDN7;
DE   RecName: Full=Alkaline ceramidase 1;
DE            Short=AlkCDase 1;
DE            Short=Alkaline CDase 1;
DE            EC=3.5.1.23;
DE   AltName: Full=Acylsphingosine deacylase 3;
DE   AltName: Full=N-acylsphingosine amidohydrolase 3;
GN   Name=ACER1; Synonyms=ASAH3;
DR   GO; GO:0017040; F:ceramidase activity; IDA:BHF-UCL.
DR   GO; GO:0071633; F:dihydroceramidase activity; IDA:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0046514; P:ceramide catabolic process; ISS:BHF-UCL.
DR   GO; GO:0008544; P:epidermis development; IEP:BHF-UCL.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEP:BHF-UCL.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0010446; P:response to alkalinity; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006665; P:sphingolipid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IDA:BHF-UCL.
//
ID   ACER2_HUMAN             Reviewed;         275 AA.
AC   Q5QJU3; A2A3R8; Q569G5; Q5VZR7; Q71RD2;
DE   RecName: Full=Alkaline ceramidase 2;
DE            Short=AlkCDase 2;
DE            Short=Alkaline CDase 2;
DE            Short=haCER2;
DE            EC=3.5.1.23;
DE   AltName: Full=Acylsphingosine deacylase 3-like;
DE   AltName: Full=N-acylsphingosine amidohydrolase 3-like;
GN   Name=ACER2; Synonyms=ASAH3L; ORFNames=PP11646;
DR   GO; GO:0017040; F:ceramidase activity; IDA:UniProtKB.
DR   GO; GO:0071633; F:dihydroceramidase activity; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0035690; P:cellular response to drug; IEP:BHF-UCL.
DR   GO; GO:0006672; P:ceramide metabolic process; IEA:InterPro.
DR   GO; GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0090285; P:negative regulation of protein glycosylation in Golgi; IMP:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB.
//
ID   ACER3_HUMAN             Reviewed;         267 AA.
AC   Q9NUN7; B2RC99;
DE   RecName: Full=Alkaline ceramidase 3;
DE            Short=AlkCDase 3;
DE            Short=Alkaline CDase 3;
DE            EC=3.5.1.-;
DE   AltName: Full=Alkaline dihydroceramidase SB89;
DE   AltName: Full=Alkaline phytoceramidase;
DE            Short=aPHC;
GN   Name=ACER3; Synonyms=APHC, PHCA;
DR   GO; GO:0070774; F:phytoceramidase activity; IDA:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; IEA:InterPro.
DR   GO; GO:0071602; P:phytosphingosine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IDA:UniProtKB.
//
ID   ACES_HUMAN              Reviewed;         614 AA.
AC   P22303; A4D2E2; B7ZKZ0; D6W5X7; Q16169; Q29S23; Q2M324; Q504V3;
AC   Q53F46; Q86TM9; Q86YX9; Q9BXP7;
DE   RecName: Full=Acetylcholinesterase;
DE            Short=AChE;
DE            EC=3.1.1.7;
DE   Flags: Precursor;
GN   Name=ACHE;
DR   GuidetoPHARMACOLOGY; 2465; -.
DR   GO; GO:0042166; F:acetylcholine binding; NAS:UniProtKB.
DR   GO; GO:0003990; F:acetylcholinesterase activity; IMP:UniProtKB.
DR   GO; GO:0001540; F:beta-amyloid binding; TAS:UniProtKB.
DR   GO; GO:0004104; F:cholinesterase activity; IDA:HGNC.
DR   GO; GO:0005518; F:collagen binding; IDA:HGNC.
DR   GO; GO:0016787; F:hydrolase activity; IDA:HGNC.
DR   GO; GO:0043236; F:laminin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0017171; F:serine hydrolase activity; IDA:HGNC.
DR   GO; GO:0006581; P:acetylcholine catabolic process; IDA:HGNC.
DR   GO; GO:0001507; P:acetylcholine catabolic process in synaptic cleft; NAS:UniProtKB.
DR   GO; GO:0042982; P:amyloid precursor protein metabolic process; TAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0019695; P:choline metabolic process; IBA:RefGenome.
DR   GO; GO:0006260; P:DNA replication; TAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:UniProtKB.
DR   GO; GO:0032223; P:negative regulation of synaptic transmission, cholinergic; IC:HGNC.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.
DR   GO; GO:0045212; P:neurotransmitter receptor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEP:HGNC.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0050714; P:positive regulation of protein secretion; TAS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IEA:Ensembl.
DR   GO; GO:0031623; P:receptor internalization; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IBA:RefGenome.
DR   GO; GO:0001919; P:regulation of receptor recycling; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; TAS:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome.
//
ID   ACE_HUMAN               Reviewed;        1306 AA.
AC   P12821; B0LPF0; B4DXI3; E7EU16; P22966; Q53YX9; Q59GY8; Q7M4L4;
DE   RecName: Full=Angiotensin-converting enzyme;
DE            Short=ACE;
DE            EC=3.2.1.-;
DE            EC=3.4.15.1;
DE   AltName: Full=Dipeptidyl carboxypeptidase I;
DE   AltName: Full=Kininase II;
DE   AltName: CD_antigen=CD143;
DE   Contains:
DE     RecName: Full=Angiotensin-converting enzyme, soluble form;
DE   Flags: Precursor;
GN   Name=ACE; Synonyms=DCP, DCP1;
DR   GuidetoPHARMACOLOGY; 1613; -.
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0031711; F:bradykinin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031404; F:chloride ion binding; IDA:BHF-UCL.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008241; F:peptidyl-dipeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
DR   GO; GO:0002005; P:angiotensin catabolic process in blood; IC:UniProtKB.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; IC:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IC:BHF-UCL.
DR   GO; GO:0042447; P:hormone catabolic process; IDA:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:0032943; P:mononuclear cell proliferation; IC:BHF-UCL.
DR   GO; GO:0043171; P:peptide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:BHF-UCL.
DR   GO; GO:0002019; P:regulation of renal output by angiotensin; IC:BHF-UCL.
DR   GO; GO:0014910; P:regulation of smooth muscle cell migration; ISS:BHF-UCL.
DR   GO; GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IC:UniProtKB.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IC:UniProtKB.
DR   GO; GO:0042312; P:regulation of vasodilation; IC:BHF-UCL.
//
ID   ACH10_HUMAN             Reviewed;         450 AA.
AC   Q9GZZ6;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-10;
DE   AltName: Full=Nicotinic acetylcholine receptor subunit alpha-10;
DE            Short=NACHR alpha-10;
DE   Flags: Precursor;
GN   Name=CHRNA10; Synonyms=NACHRA10;
DR   GuidetoPHARMACOLOGY; 470; -.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:receptor binding; TAS:UniProtKB.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IGI:MGI.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; TAS:UniProtKB.
//
ID   ACHA2_HUMAN             Reviewed;         529 AA.
AC   Q15822; A8KAX3; Q9HAQ3;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-2;
DE   Flags: Precursor;
GN   Name=CHRNA2;
DR   GuidetoPHARMACOLOGY; 463; -.
DR   GO; GO:0042166; F:acetylcholine binding; IEA:Ensembl.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   ACHA3_HUMAN             Reviewed;         505 AA.
AC   P32297; Q15823; Q4KMN8; Q86U77; Q96RH3; Q99553; Q9BQ93; Q9BRR4;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-3;
DE   Flags: Precursor;
GN   Name=CHRNA3; Synonyms=NACHRA3;
DR   GuidetoPHARMACOLOGY; 464; -.
DR   GO; GO:0042166; F:acetylcholine binding; IC:UniProtKB.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IDA:UniProtKB.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:DFLAT.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0035095; P:behavioral response to nicotine; IMP:UniProtKB.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0014056; P:regulation of acetylcholine secretion, neurotransmission; ISS:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; ISS:UniProtKB.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0060084; P:synaptic transmission involved in micturition; IMP:UniProtKB.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; ISS:UniProtKB.
//
ID   ACHA4_HUMAN             Reviewed;         627 AA.
AC   P43681; Q4JGR7; Q4VAQ5; Q4VAQ6;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-4;
DE   Flags: Precursor;
GN   Name=CHRNA4; Synonyms=NACRA4;
DR   GuidetoPHARMACOLOGY; 465; -.
DR   GO; GO:0042166; F:acetylcholine binding; IC:UniProtKB.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IDA:UniProtKB.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:DFLAT.
DR   GO; GO:0001508; P:action potential; ISS:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; ISS:UniProtKB.
DR   GO; GO:0035095; P:behavioral response to nicotine; IMP:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0035640; P:exploration behavior; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; ISS:UniProtKB.
DR   GO; GO:0050877; P:neurological system process; IMP:UniProtKB.
DR   GO; GO:0014059; P:regulation of dopamine secretion; ISS:UniProtKB.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; ISS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; ISS:UniProtKB.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0035094; P:response to nicotine; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; ISS:UniProtKB.
//
ID   ACHA5_HUMAN             Reviewed;         468 AA.
AC   P30532; Q15824; Q99554;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-5;
DE   Flags: Precursor;
GN   Name=CHRNA5; Synonyms=NACHRA5;
DR   GuidetoPHARMACOLOGY; 466; -.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; NAS:UniProtKB.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:DFLAT.
DR   GO; GO:0035095; P:behavioral response to nicotine; IMP:UniProtKB.
DR   GO; GO:0006812; P:cation transport; NAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   ACHA6_HUMAN             Reviewed;         494 AA.
AC   Q15825; B2R8V4; B4DQH1;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-6;
DE   Flags: Precursor;
GN   Name=CHRNA6;
DR   GuidetoPHARMACOLOGY; 467; -.
DR   GO; GO:0015464; F:acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0051899; P:membrane depolarization; IEA:Ensembl.
DR   GO; GO:0014059; P:regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACHA7_HUMAN             Reviewed;         502 AA.
AC   P36544; A8K7Q4; B4DFS0; Q15826; Q8IUZ4; Q96RH2; Q99555; Q9BXH0;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-7;
DE   Flags: Precursor;
GN   Name=CHRNA7; Synonyms=NACHRA7;
DR   GuidetoPHARMACOLOGY; 468; -.
DR   GO; GO:0042166; F:acetylcholine binding; IDA:UniProtKB.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IDA:UniProtKB.
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:UniProtKB.
DR   GO; GO:0017081; F:chloride channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0015643; F:toxic substance binding; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0042113; P:B cell activation; IEA:Ensembl.
DR   GO; GO:0048149; P:behavioral response to ethanol; IEA:Ensembl.
DR   GO; GO:0035095; P:behavioral response to nicotine; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0060112; P:generation of ovulation cycle rhythm; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0007613; P:memory; NAS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001988; P:positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0014061; P:regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0032225; P:regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0035094; P:response to nicotine; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
//
ID   ACHA9_HUMAN             Reviewed;         479 AA.
AC   Q9UGM1; Q14CY7; Q4W5A2; Q9NYV2;
DE   RecName: Full=Neuronal acetylcholine receptor subunit alpha-9;
DE   AltName: Full=Nicotinic acetylcholine receptor subunit alpha-9;
DE            Short=NACHR alpha-9;
DE   Flags: Precursor;
GN   Name=CHRNA9; Synonyms=NACHRA9;
DR   GuidetoPHARMACOLOGY; 469; -.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IGI:MGI.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   ACHA_HUMAN              Reviewed;         482 AA.
AC   P02708; B4DRV6; D3DPE8;
DE   RecName: Full=Acetylcholine receptor subunit alpha;
DE   Flags: Precursor;
GN   Name=CHRNA1; Synonyms=ACHRA, CHNRA;
DR   GuidetoPHARMACOLOGY; 462; -.
DR   GO; GO:0042166; F:acetylcholine binding; IEA:Ensembl.
DR   GO; GO:0015464; F:acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IMP:MGI.
DR   GO; GO:0005216; F:ion channel activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; IMP:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IMP:BHF-UCL.
DR   GO; GO:0050881; P:musculoskeletal movement; IMP:BHF-UCL.
DR   GO; GO:0007528; P:neuromuscular junction development; IMP:MGI.
DR   GO; GO:0050905; P:neuromuscular process; IMP:BHF-UCL.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IMP:MGI.
DR   GO; GO:0070050; P:neuron cellular homeostasis; IMP:BHF-UCL.
DR   GO; GO:0019228; P:neuronal action potential; IMP:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0003009; P:skeletal muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0048630; P:skeletal muscle tissue growth; IMP:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACHB2_HUMAN             Reviewed;         502 AA.
AC   P17787; Q9UEH9;
DE   RecName: Full=Neuronal acetylcholine receptor subunit beta-2;
DE   Flags: Precursor;
GN   Name=CHRNB2;
DR   GuidetoPHARMACOLOGY; 472; -.
DR   GO; GO:0042166; F:acetylcholine binding; IMP:UniProtKB.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:DFLAT.
DR   GO; GO:0001508; P:action potential; IEA:Ensembl.
DR   GO; GO:0008306; P:associative learning; ISS:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; ISS:UniProtKB.
DR   GO; GO:0035095; P:behavioral response to nicotine; IMP:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; ISS:UniProtKB.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0001661; P:conditioned taste aversion; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0021771; P:lateral geniculate nucleus development; ISS:UniProtKB.
DR   GO; GO:0007612; P:learning; IMP:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0051899; P:membrane depolarization; ISS:UniProtKB.
DR   GO; GO:0007613; P:memory; IMP:UniProtKB.
DR   GO; GO:0045759; P:negative regulation of action potential; ISS:UniProtKB.
DR   GO; GO:0050877; P:neurological system process; IMP:UniProtKB.
DR   GO; GO:0021631; P:optic nerve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0033603; P:positive regulation of dopamine secretion; ISS:UniProtKB.
DR   GO; GO:0032226; P:positive regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0045188; P:regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0042320; P:regulation of circadian sleep/wake cycle, REM sleep; ISS:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0014059; P:regulation of dopamine secretion; ISS:UniProtKB.
DR   GO; GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0032225; P:regulation of synaptic transmission, dopaminergic; ISS:UniProtKB.
DR   GO; GO:0042220; P:response to cocaine; ISS:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; ISS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0035094; P:response to nicotine; IDA:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0006939; P:smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0035176; P:social behavior; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0060084; P:synaptic transmission involved in micturition; ISS:UniProtKB.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; ISS:UniProtKB.
DR   GO; GO:0021562; P:vestibulocochlear nerve development; ISS:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IMP:UniProtKB.
DR   GO; GO:0007601; P:visual perception; ISS:UniProtKB.
//
ID   ACHB3_HUMAN             Reviewed;         458 AA.
AC   Q05901; Q15827;
DE   RecName: Full=Neuronal acetylcholine receptor subunit beta-3;
DE   Flags: Precursor;
GN   Name=CHRNB3;
DR   GuidetoPHARMACOLOGY; 473; -.
DR   GO; GO:0042166; F:acetylcholine binding; IEA:Ensembl.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; TAS:ProtInc.
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACHB4_HUMAN             Reviewed;         498 AA.
AC   P30926; A4FTX5; E9PHE8; Q16607; Q4VBA5; Q8WXC8; Q9BQR4;
DE   RecName: Full=Neuronal acetylcholine receptor subunit beta-4;
DE   Flags: Precursor;
GN   Name=CHRNB4;
DR   GuidetoPHARMACOLOGY; 474; -.
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; TAS:UniProtKB.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:DFLAT.
DR   GO; GO:0001508; P:action potential; IEA:Ensembl.
DR   GO; GO:0035095; P:behavioral response to nicotine; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; NAS:UniProtKB.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0006939; P:smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0060084; P:synaptic transmission involved in micturition; IMP:UniProtKB.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; TAS:ProtInc.
//
ID   ACHB_HUMAN              Reviewed;         501 AA.
AC   P11230; Q8IZ46; Q96FB8;
DE   RecName: Full=Acetylcholine receptor subunit beta;
DE   Flags: Precursor;
GN   Name=CHRNB1; Synonyms=ACHRB, CHRNB;
DR   GuidetoPHARMACOLOGY; 471; -.
DR   GO; GO:0042166; F:acetylcholine binding; ISS:UniProtKB.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IEA:Ensembl.
DR   GO; GO:0015267; F:channel activity; IMP:UniProtKB.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; ISS:UniProtKB.
DR   GO; GO:0035095; P:behavioral response to nicotine; IMP:UniProtKB.
DR   GO; GO:0006812; P:cation transport; IMP:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; ISS:GOC.
DR   GO; GO:0006936; P:muscle contraction; IMP:UniProtKB.
DR   GO; GO:0048747; P:muscle fiber development; IMP:UniProtKB.
DR   GO; GO:0050877; P:neurological system process; IMP:UniProtKB.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IMP:UniProtKB.
DR   GO; GO:0001941; P:postsynaptic membrane organization; IMP:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; IMP:GOC.
//
ID   ACHD_HUMAN              Reviewed;         517 AA.
AC   Q07001; A8K661; B4DT92; Q52LH4;
DE   RecName: Full=Acetylcholine receptor subunit delta;
DE   Flags: Precursor;
GN   Name=CHRND; Synonyms=ACHRD;
DR   GuidetoPHARMACOLOGY; 476; -.
DR   GO; GO:0042166; F:acetylcholine binding; IEA:Ensembl.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0050881; P:musculoskeletal movement; IMP:BHF-UCL.
DR   GO; GO:0050905; P:neuromuscular process; NAS:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048630; P:skeletal muscle tissue growth; IMP:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACHE_HUMAN              Reviewed;         493 AA.
AC   Q04844; D3DTK6;
DE   RecName: Full=Acetylcholine receptor subunit epsilon;
DE   Flags: Precursor;
GN   Name=CHRNE; Synonyms=ACHRE;
DR   GuidetoPHARMACOLOGY; 477; -.
DR   GO; GO:0015464; F:acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; TAS:ProtInc.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACHG_HUMAN              Reviewed;         517 AA.
AC   P07510; B3KWM8; Q53RG2;
DE   RecName: Full=Acetylcholine receptor subunit gamma;
DE   Flags: Precursor;
GN   Name=CHRNG; Synonyms=ACHRG;
DR   GuidetoPHARMACOLOGY; 475; -.
DR   GO; GO:0015464; F:acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004889; F:acetylcholine-activated cation-selective channel activity; IEA:Ensembl.
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ACINU_HUMAN             Reviewed;        1341 AA.
AC   Q9UKV3; B2RTT4; D3DS45; O75158; Q9UG91; Q9UKV1; Q9UKV2;
DE   RecName: Full=Apoptotic chromatin condensation inducer in the nucleus;
DE            Short=Acinus;
GN   Name=ACIN1; Synonyms=ACINUS, KIAA0670;
DR   GO; GO:0016887; F:ATPase activity; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030263; P:apoptotic chromosome condensation; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045657; P:positive regulation of monocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   ACK1_HUMAN              Reviewed;        1038 AA.
AC   Q07912; Q6ZMQ0; Q8N6U7; Q96H59;
DE   RecName: Full=Activated CDC42 kinase 1;
DE            Short=ACK-1;
DE            EC=2.7.10.2;
DE            EC=2.7.11.1;
DE   AltName: Full=Tyrosine kinase non-receptor protein 2;
GN   Name=TNK2; Synonyms=ACK1;
DR   GuidetoPHARMACOLOGY; 2246; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; ISS:BHF-UCL.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   ACKR1_HUMAN             Reviewed;         336 AA.
AC   Q16570; A8YPG5; O75898; Q16300; Q8WWE3; Q9UJP0; Q9UKZ5; Q9UKZ6;
AC   Q9UQE1;
DE   RecName: Full=Atypical chemokine receptor 1;
DE   AltName: Full=Duffy antigen/chemokine receptor;
DE   AltName: Full=Fy glycoprotein;
DE            Short=GpFy;
DE   AltName: Full=Glycoprotein D;
DE   AltName: Full=Plasmodium vivax receptor;
DE   AltName: CD_antigen=CD234;
GN   Name=ACKR1; Synonyms=DARC, FY, GPD;
DR   GO; GO:0019957; F:C-C chemokine binding; IPI:BHF-UCL.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0032642; P:regulation of chemokine production; IEA:Ensembl.
//
ID   ACKR2_HUMAN             Reviewed;         384 AA.
AC   O00590; B2R8Y8; O00537; Q53YA1; Q86UN9; Q96A02;
DE   RecName: Full=Atypical chemokine receptor 2;
DE   AltName: Full=C-C chemokine receptor D6;
DE   AltName: Full=Chemokine receptor CCR-10;
DE   AltName: Full=Chemokine receptor CCR-9;
DE   AltName: Full=Chemokine-binding protein 2;
DE   AltName: Full=Chemokine-binding protein D6;
GN   Name=ACKR2; Synonyms=CCBP2, CCR10, CMKBR9, D6;
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; IEA:InterPro.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0005044; F:scavenger receptor activity; IMP:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0042119; P:neutrophil activation; IEA:InterPro.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:GOC.
//
ID   ACKR3_HUMAN             Reviewed;         362 AA.
AC   P25106; A8K6J4; Q53RV4; Q8NE10; Q92938; Q92986;
DE   RecName: Full=Atypical chemokine receptor 3;
DE   AltName: Full=C-X-C chemokine receptor type 7;
DE            Short=CXC-R7;
DE            Short=CXCR-7;
DE   AltName: Full=Chemokine orphan receptor 1;
DE   AltName: Full=G-protein coupled receptor 159;
DE   AltName: Full=G-protein coupled receptor RDC1 homolog;
DE            Short=RDC-1;
GN   Name=ACKR3; Synonyms=CMKOR1, CXCR7, GPR159, RDC1;
DR   GuidetoPHARMACOLOGY; 80; -.
DR   GO; GO:0019958; F:C-X-C chemokine binding; IMP:UniProtKB.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; IMP:BHF-UCL.
DR   GO; GO:0015026; F:coreceptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IMP:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ACKR4_HUMAN             Reviewed;         350 AA.
AC   Q9NPB9; B2R9U7;
DE   RecName: Full=Atypical chemokine receptor 4;
DE   AltName: Full=C-C chemokine receptor type 11;
DE            Short=C-C CKR-11;
DE            Short=CC-CKR-11;
DE            Short=CCR-11;
DE   AltName: Full=CC chemokine receptor-like 1;
DE            Short=CCRL1;
DE   AltName: Full=CCX CKR;
GN   Name=ACKR4; Synonyms=CCBP2, CCR11, CCRL1, VSHK1;
DR   GuidetoPHARMACOLOGY; 315; -.
DR   GO; GO:0004950; F:chemokine receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   ACL10_HUMAN             Reviewed;         245 AA.
AC   Q5JWF8; B9EH76;
DE   RecName: Full=Actin-like protein 10;
GN   Name=ACTL10; Synonyms=C20orf134;
//
ID   ACL6A_HUMAN             Reviewed;         429 AA.
AC   O96019; B3KMN1; D3DNR9; Q8TAE5; Q9BVS8; Q9H0W6;
DE   RecName: Full=Actin-like protein 6A;
DE   AltName: Full=53 kDa BRG1-associated factor A;
DE   AltName: Full=Actin-related protein Baf53a;
DE   AltName: Full=ArpNbeta;
DE   AltName: Full=BRG1-associated factor 53A;
DE            Short=BAF53A;
DE   AltName: Full=INO80 complex subunit K;
GN   Name=ACTL6A; Synonyms=BAF53, BAF53A, INO80K;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0003407; P:neural retina development; IEP:BHF-UCL.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ACL6B_HUMAN             Reviewed;         426 AA.
AC   O94805; A4D2D0; O75421;
DE   RecName: Full=Actin-like protein 6B;
DE   AltName: Full=53 kDa BRG1-associated factor B;
DE   AltName: Full=Actin-related protein Baf53b;
DE   AltName: Full=ArpNalpha;
DE   AltName: Full=BRG1-associated factor 53B;
DE            Short=BAF53B;
GN   Name=ACTL6B; Synonyms=ACTL6, BAF53B;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ACL7A_HUMAN             Reviewed;         435 AA.
AC   Q9Y615; B2RC83; Q5JSV0;
DE   RecName: Full=Actin-like protein 7A;
DE   AltName: Full=Actin-like-7-alpha;
GN   Name=ACTL7A;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
//
ID   ACL7B_HUMAN             Reviewed;         415 AA.
AC   Q9Y614; B2R9Q2; Q5JSV1;
DE   RecName: Full=Actin-like protein 7B;
DE   AltName: Full=Actin-like-7-beta;
GN   Name=ACTL7B;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
//
ID   ACLY_HUMAN              Reviewed;        1101 AA.
AC   P53396; B4DIM0; Q13037; Q9BRL0;
DE   RecName: Full=ATP-citrate synthase;
DE            EC=2.3.3.8;
DE   AltName: Full=ATP-citrate (pro-S-)-lyase;
DE            Short=ACL;
DE   AltName: Full=Citrate cleavage enzyme;
GN   Name=ACLY;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003878; F:ATP citrate synthase activity; TAS:UniProtKB.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:ProtInc.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006101; P:citrate metabolic process; TAS:ProtInc.
DR   GO; GO:0015936; P:coenzyme A metabolic process; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0008610; P:lipid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   ACM1_HUMAN              Reviewed;         460 AA.
AC   P11229;
DE   RecName: Full=Muscarinic acetylcholine receptor M1;
GN   Name=CHRM1;
DR   GuidetoPHARMACOLOGY; 13; -.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0016907; F:G-protein coupled acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0050890; P:cognition; IEA:InterPro.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007207; P:phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0043270; P:positive regulation of ion transport; IGI:MGI.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0040012; P:regulation of locomotion; IEA:Ensembl.
DR   GO; GO:0046541; P:saliva secretion; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ACM2_HUMAN              Reviewed;         466 AA.
AC   P08172; Q4VBK6; Q9P1X9;
DE   RecName: Full=Muscarinic acetylcholine receptor M2;
GN   Name=CHRM2;
DR   GuidetoPHARMACOLOGY; 14; -.
DR   GO; GO:0016907; F:G-protein coupled acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007207; P:phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   ACM3_HUMAN              Reviewed;         590 AA.
AC   P20309; Q0VAJ8; Q4QRI3; Q5VXY2; Q9HB60;
DE   RecName: Full=Muscarinic acetylcholine receptor M3;
GN   Name=CHRM3;
DR   GuidetoPHARMACOLOGY; 15; -.
DR   GO; GO:0042166; F:acetylcholine binding; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0016907; F:G-protein coupled acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0003056; P:regulation of vascular smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0046541; P:saliva secretion; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006939; P:smooth muscle contraction; IEA:Ensembl.
//
ID   ACM4_HUMAN              Reviewed;         479 AA.
AC   P08173; B2RPP4; Q0VD60; Q4VBK7;
DE   RecName: Full=Muscarinic acetylcholine receptor M4;
GN   Name=CHRM4;
DR   GuidetoPHARMACOLOGY; 16; -.
DR   GO; GO:0016907; F:G-protein coupled acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0007197; P:adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0040012; P:regulation of locomotion; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ACM5_HUMAN              Reviewed;         532 AA.
AC   P08912; Q96RG7;
DE   RecName: Full=Muscarinic acetylcholine receptor M5;
GN   Name=CHRM5;
DR   GuidetoPHARMACOLOGY; 17; -.
DR   GO; GO:0016907; F:G-protein coupled acetylcholine receptor activity; TAS:ProtInc.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007197; P:adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0015872; P:dopamine transport; IEA:Ensembl.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001696; P:gastric acid secretion; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0060304; P:regulation of phosphatidylinositol dephosphorylation; IEA:Ensembl.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   ACMSD_HUMAN             Reviewed;         336 AA.
AC   Q8TDX5; Q3B7X3; Q53SR5; Q96KY2;
DE   RecName: Full=2-amino-3-carboxymuconate-6-semialdehyde decarboxylase;
DE            EC=4.1.1.45;
DE   AltName: Full=Picolinate carboxylase;
GN   Name=ACMSD;
DR   GO; GO:0001760; F:aminocarboxymuconate-semialdehyde decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0046874; P:quinolinate metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
//
ID   ACN9_HUMAN              Reviewed;         125 AA.
AC   Q9NRP4; A4D1J3; Q75MD6;
DE   RecName: Full=Protein ACN9 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=ACN9; ORFNames=DC11;
DR   GO; GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
//
ID   ACO11_HUMAN             Reviewed;         607 AA.
AC   Q8WXI4; B1AQ22; D3DQ50; O75187; Q52LP1; Q53ER9; Q96DI1; Q9H883;
DE   RecName: Full=Acyl-coenzyme A thioesterase 11;
DE            Short=Acyl-CoA thioesterase 11;
DE            EC=3.1.2.-;
DE   AltName: Full=Acyl-CoA thioester hydrolase 11;
DE   AltName: Full=Adipose-associated thioesterase;
DE   AltName: Full=Brown fat-inducible thioesterase;
DE            Short=BFIT;
GN   Name=ACOT11; Synonyms=BFIT, KIAA0707, THEA;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; TAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0009409; P:response to cold; ISS:BHF-UCL.
DR   GO; GO:0009266; P:response to temperature stimulus; ISS:UniProtKB.
//
ID   ACO12_HUMAN             Reviewed;         555 AA.
AC   Q8WYK0; B3KVK9;
DE   RecName: Full=Acyl-coenzyme A thioesterase 12;
DE            Short=Acyl-CoA thioesterase 12;
DE            EC=3.1.2.1;
DE   AltName: Full=Acyl-CoA thioester hydrolase 12;
DE   AltName: Full=Cytoplasmic acetyl-CoA hydrolase 1;
DE            Short=CACH-1;
DE            Short=hCACH-1;
DE   AltName: Full=START domain-containing protein 15;
DE            Short=StARD15;
GN   Name=ACOT12; Synonyms=CACH, CACH1, STARD15;
DR   GO; GO:0003986; F:acetyl-CoA hydrolase activity; ISS:HGNC.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; ISS:HGNC.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006090; P:pyruvate metabolic process; IEA:UniProtKB-UniPathway.
//
ID   ACO13_HUMAN             Reviewed;         140 AA.
AC   Q9NPJ3; F5H2L4; O95549;
DE   RecName: Full=Acyl-coenzyme A thioesterase 13;
DE            Short=Acyl-CoA thioesterase 13;
DE            EC=3.1.2.-;
DE   AltName: Full=Thioesterase superfamily member 2;
DE   Contains:
DE     RecName: Full=Acyl-coenzyme A thioesterase 13, N-terminally processed;
GN   Name=ACOT13; Synonyms=THEM2; ORFNames=HT012, PNAS-27;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
//
ID   ACO15_HUMAN             Reviewed;         247 AA.
AC   Q8N1Q8; Q5T1C3;
DE   RecName: Full=Acyl-coenzyme A thioesterase THEM5;
DE            Short=Acyl-CoA thioesterase THEM5;
DE            EC=3.1.2.2;
DE   AltName: Full=Acyl-coenzyme A thioesterase 15;
DE   AltName: Full=Thioesterase superfamily member 5;
GN   Name=THEM5; Synonyms=ACOT15;
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; ISS:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035336; P:long-chain fatty-acyl-CoA metabolic process; IDA:UniProtKB.
//
ID   ACOC_HUMAN              Reviewed;         889 AA.
AC   P21399; D3DRK7; Q14652; Q5VZA7;
DE   RecName: Full=Cytoplasmic aconitate hydratase;
DE            Short=Aconitase;
DE            EC=4.2.1.3;
DE   AltName: Full=Citrate hydro-lyase;
DE   AltName: Full=Ferritin repressor protein;
DE   AltName: Full=Iron regulatory protein 1;
DE            Short=IRP1;
DE   AltName: Full=Iron-responsive element-binding protein 1;
DE            Short=IRE-BP 1;
GN   Name=ACO1; Synonyms=IREB1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0003994; F:aconitate hydratase activity; IDA:UniProtKB.
DR   GO; GO:0030350; F:iron-responsive element binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006101; P:citrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
DR   GO; GO:0010040; P:response to iron(II) ion; IDA:UniProtKB.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
//
ID   ACOD_HUMAN              Reviewed;         359 AA.
AC   O00767; B2R5U0; D3DR68; Q16150; Q53GR9; Q5W037; Q5W038; Q6GSS4;
AC   Q96KF6; Q9BS07; Q9Y695;
DE   RecName: Full=Acyl-CoA desaturase;
DE            EC=1.14.19.1;
DE   AltName: Full=Delta(9)-desaturase;
DE            Short=Delta-9 desaturase;
DE   AltName: Full=Fatty acid desaturase;
DE   AltName: Full=Stearoyl-CoA desaturase;
GN   Name=SCD;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004768; F:stearoyl-CoA 9-desaturase activity; TAS:ProtInc.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
//
ID   ACON_HUMAN              Reviewed;         780 AA.
AC   Q99798; O75809; Q5JZ41; Q6FHX0; Q8TAQ6;
DE   RecName: Full=Aconitate hydratase, mitochondrial;
DE            Short=Aconitase;
DE            EC=4.2.1.3;
DE   AltName: Full=Citrate hydro-lyase;
DE   Flags: Precursor;
GN   Name=ACO2;
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:Ensembl.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003994; F:aconitate hydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005506; F:iron ion binding; IDA:MGI.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006101; P:citrate metabolic process; IDA:MGI.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006102; P:isocitrate metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IDA:MGI.
//
ID   ACOT1_HUMAN             Reviewed;         421 AA.
AC   Q86TX2; A1L173; Q3I5F9;
DE   RecName: Full=Acyl-coenzyme A thioesterase 1;
DE            Short=Acyl-CoA thioesterase 1;
DE            EC=3.1.2.2;
DE   AltName: Full=CTE-I;
DE   AltName: Full=CTE-Ib;
DE   AltName: Full=Inducible cytosolic acyl-coenzyme A thioester hydrolase;
DE   AltName: Full=Long chain acyl-CoA thioester hydrolase;
DE            Short=Long chain acyl-CoA hydrolase;
GN   Name=ACOT1; Synonyms=CTE1;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IDA:HGNC.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:HGNC.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:HGNC.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:HGNC.
//
ID   ACOT2_HUMAN             Reviewed;         483 AA.
AC   P49753; Q3I5F8; Q53EK4; Q9NUX4;
DE   RecName: Full=Acyl-coenzyme A thioesterase 2, mitochondrial;
DE            Short=Acyl-CoA thioesterase 2;
DE            EC=3.1.2.2;
DE   AltName: Full=Acyl-coenzyme A thioester hydrolase 2a;
DE   AltName: Full=CTE-Ia;
DE   AltName: Full=Long-chain acyl-CoA thioesterase 2;
DE   AltName: Full=ZAP128;
DE   Flags: Precursor;
GN   Name=ACOT2; Synonyms=PTE2, PTE2A;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IDA:HGNC.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:HGNC.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:HGNC.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:HGNC.
//
ID   ACOT4_HUMAN             Reviewed;         421 AA.
AC   Q8N9L9; Q17RF4; Q5BKT6; Q86TX0; Q86TX1; Q96N88;
DE   RecName: Full=Acyl-coenzyme A thioesterase 4;
DE            Short=Acyl-CoA thioesterase 4;
DE            EC=3.1.2.2;
DE   AltName: Full=PTE-2b;
DE   AltName: Full=Peroxisomal acyl coenzyme A thioester hydrolase Ib;
DE   AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase Ib;
DE            Short=PTE-Ib;
GN   Name=ACOT4; Synonyms=PTE2B, PTEIB;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0004778; F:succinyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:HGNC.
DR   GO; GO:0043649; P:dicarboxylic acid catabolic process; IDA:UniProtKB.
DR   GO; GO:0043648; P:dicarboxylic acid metabolic process; IDA:HGNC.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:HGNC.
DR   GO; GO:0032788; P:saturated monocarboxylic acid metabolic process; IDA:HGNC.
DR   GO; GO:0046459; P:short-chain fatty acid metabolic process; IDA:HGNC.
DR   GO; GO:0006104; P:succinyl-CoA metabolic process; IDA:HGNC.
DR   GO; GO:0032789; P:unsaturated monocarboxylic acid metabolic process; IDA:HGNC.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:HGNC.
//
ID   ACOT6_HUMAN             Reviewed;         207 AA.
AC   Q3I5F7;
DE   RecName: Full=Putative acyl-coenzyme A thioesterase 6;
DE            Short=Putative acyl-CoA thioesterase 6;
DE            EC=3.1.2.-;
GN   Name=ACOT6; Synonyms=C14orf42;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ACOT8_HUMAN             Reviewed;         319 AA.
AC   O14734; O15261; Q17RX4;
DE   RecName: Full=Acyl-coenzyme A thioesterase 8;
DE            Short=Acyl-CoA thioesterase 8;
DE            EC=3.1.2.27;
DE   AltName: Full=Choloyl-coenzyme A thioesterase;
DE   AltName: Full=HIV-Nef-associated acyl-CoA thioesterase;
DE   AltName: Full=PTE-2;
DE   AltName: Full=Peroxisomal acyl-coenzyme A thioester hydrolase 1;
DE            Short=PTE-1;
DE   AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase 1;
DE   AltName: Full=Thioesterase II;
DE            Short=hACTE-III;
DE            Short=hACTEIII;
DE            Short=hTE;
GN   Name=ACOT8; Synonyms=ACTEIII, PTE1, PTE2;
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0033882; F:choloyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052815; F:medium-chain acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0043649; P:dicarboxylic acid catabolic process; IDA:UniProtKB.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0016559; P:peroxisome fission; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ACOT9_HUMAN             Reviewed;         439 AA.
AC   Q9Y305; B3KNC9; B7ZM94;
DE   RecName: Full=Acyl-coenzyme A thioesterase 9, mitochondrial;
DE            Short=Acyl-CoA thioesterase 9;
DE            EC=3.1.2.-;
DE   AltName: Full=Acyl-CoA thioester hydrolase 9;
DE   Flags: Precursor;
GN   Name=ACOT9; ORFNames=CGI-16;
DR   GO; GO:0003986; F:acetyl-CoA hydrolase activity; ISS:HGNC.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; ISS:HGNC.
//
ID   ACOX1_HUMAN             Reviewed;         660 AA.
AC   Q15067; A8K6X8; A8KAA0; B4DK61; F5GYQ8; Q12863; Q15068; Q15101;
AC   Q16131; Q7Z3W5; Q9UD31;
DE   RecName: Full=Peroxisomal acyl-coenzyme A oxidase 1;
DE            Short=AOX;
DE            EC=1.3.3.6;
DE   AltName: Full=Palmitoyl-CoA oxidase;
DE   AltName: Full=Straight-chain acyl-CoA oxidase;
DE            Short=SCOX;
GN   Name=ACOX1; Synonyms=ACOX;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0003997; F:acyl-CoA oxidase activity; IDA:UniProtKB.
DR   GO; GO:0071949; F:FAD binding; IDA:UniProtKB.
DR   GO; GO:0005504; F:fatty acid binding; IEA:Ensembl.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016401; F:palmitoyl-CoA oxidase activity; IDA:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:MGI.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; IMP:BHF-UCL.
DR   GO; GO:0019395; P:fatty acid oxidation; IGI:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IMP:UniProtKB.
DR   GO; GO:0055088; P:lipid homeostasis; IDA:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; IDA:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IGI:UniProtKB.
DR   GO; GO:2000189; P:positive regulation of cholesterol homeostasis; IGI:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IMP:BHF-UCL.
//
ID   ACOX2_HUMAN             Reviewed;         681 AA.
AC   Q99424; A6NF16; B2R8U5;
DE   RecName: Full=Peroxisomal acyl-coenzyme A oxidase 2;
DE            EC=1.17.99.3;
DE   AltName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase;
DE   AltName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase;
DE   AltName: Full=Trihydroxycoprostanoyl-CoA oxidase;
DE            Short=THCA-CoA oxidase;
DE            Short=THCCox;
GN   Name=ACOX2;
DR   GO; GO:0033791; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0003997; F:acyl-CoA oxidase activity; TAS:Reactome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016402; F:pristanoyl-CoA oxidase activity; TAS:Reactome.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ACOX3_HUMAN             Reviewed;         700 AA.
AC   O15254; Q96AJ8;
DE   RecName: Full=Peroxisomal acyl-coenzyme A oxidase 3;
DE            EC=1.3.3.6;
DE   AltName: Full=Branched-chain acyl-CoA oxidase;
DE            Short=BRCACox;
DE   AltName: Full=Pristanoyl-CoA oxidase;
GN   Name=ACOX3; Synonyms=BRCOX, PRCOX;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016402; F:pristanoyl-CoA oxidase activity; TAS:Reactome.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ACOXL_HUMAN             Reviewed;         547 AA.
AC   Q9NUZ1; A2RRB7; B7WPB3; B7WPP7; E9PB20; Q53R27; Q53R31; Q53SC6;
AC   Q8TCE7;
DE   RecName: Full=Acyl-coenzyme A oxidase-like protein;
DE            Short=Acyl-CoA oxidase-like protein;
DE            EC=1.3.3.-;
GN   Name=ACOXL;
DR   GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0003997; F:acyl-CoA oxidase activity; IEA:InterPro.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:InterPro.
//
ID   ACPH_HUMAN              Reviewed;         732 AA.
AC   P13798; Q9BQ33; Q9P0Y2;
DE   RecName: Full=Acylamino-acid-releasing enzyme;
DE            Short=AARE;
DE            EC=3.4.19.1;
DE   AltName: Full=Acyl-peptide hydrolase;
DE            Short=APH;
DE   AltName: Full=Acylaminoacyl-peptidase;
DE   AltName: Full=Oxidized protein hydrolase;
DE            Short=OPH;
GN   Name=APEH; Synonyms=D3F15S2, D3S48E, DNF15S2;
DR   GO; GO:0008242; F:omega peptidase activity; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProt.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IDA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProt.
//
ID   ACPL2_HUMAN             Reviewed;         480 AA.
AC   Q8TE99; D3DNF5; Q49AJ2;
DE   RecName: Full=Acid phosphatase-like protein 2;
DE            EC=3.1.3.2;
DE   Flags: Precursor;
GN   Name=ACPL2; ORFNames=UNQ370/PRO706;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
//
ID   ACPM_HUMAN              Reviewed;         156 AA.
AC   O14561; B2R4M1; Q9UNV1;
DE   RecName: Full=Acyl carrier protein, mitochondrial;
DE            Short=ACP;
DE   AltName: Full=CI-SDAP;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 9.6 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFAB1;
DR   GO; GO:0000036; F:ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0005504; F:fatty acid binding; ISS:UniProtKB.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0009249; P:protein lipoylation; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ACRBP_HUMAN             Reviewed;         543 AA.
AC   Q8NEB7; Q9BY87;
DE   RecName: Full=Acrosin-binding protein;
DE   AltName: Full=Cancer/testis antigen 23;
DE            Short=CT23;
DE   AltName: Full=Cancer/testis antigen OY-TES-1;
DE   AltName: Full=Proacrosin-binding protein sp32;
DE   Flags: Precursor;
GN   Name=ACRBP;
//
ID   ACRC_HUMAN              Reviewed;         691 AA.
AC   Q96QF7; B9EG62;
DE   RecName: Full=Acidic repeat-containing protein;
GN   Name=ACRC;
//
ID   ACRO_HUMAN              Reviewed;         421 AA.
AC   P10323; Q6ICK2;
DE   RecName: Full=Acrosin;
DE            EC=3.4.21.10;
DE   Contains:
DE     RecName: Full=Acrosin light chain;
DE   Contains:
DE     RecName: Full=Acrosin heavy chain;
DE   Flags: Precursor;
GN   Name=ACR; Synonyms=ACRS;
DR   GO; GO:0004040; F:amidase activity; ISS:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008144; F:drug binding; ISS:UniProtKB.
DR   GO; GO:0042806; F:fucose binding; ISS:UniProtKB.
DR   GO; GO:0005537; F:mannose binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0002077; P:acrosome matrix dispersal; NAS:UniProtKB.
DR   GO; GO:0007340; P:acrosome reaction; IMP:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; ISS:UniProtKB.
//
ID   ACS2A_HUMAN             Reviewed;         577 AA.
AC   Q08AH3; B3KTT9; O75202;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM2A, mitochondrial;
DE            EC=6.2.1.2;
DE   AltName: Full=Acyl-CoA synthetase medium-chain family member 2A;
DE   AltName: Full=Butyrate--CoA ligase 2A;
DE   AltName: Full=Butyryl-coenzyme A synthetase 2A;
DE   AltName: Full=Middle-chain acyl-CoA synthetase 2A;
DE   Flags: Precursor;
GN   Name=ACSM2A; Synonyms=ACSM2, MACS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0042593; P:glucose homeostasis; NAS:BHF-UCL.
DR   GO; GO:0036112; P:medium-chain fatty-acyl-CoA metabolic process; IDA:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; NAS:BHF-UCL.
//
ID   ACS2B_HUMAN             Reviewed;         577 AA.
AC   Q68CK6; Q86YT1;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM2B, mitochondrial;
DE            EC=6.2.1.2;
DE   AltName: Full=Acyl-CoA synthetase medium-chain family member 2B;
DE   AltName: Full=Butyrate--CoA ligase 2B;
DE   AltName: Full=Butyryl-coenzyme A synthetase 2B;
DE   AltName: Full=Middle-chain acyl-CoA synthetase 2B;
DE   AltName: Full=Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A;
DE   Flags: Precursor;
GN   Name=ACSM2B; Synonyms=ACSM2; ORFNames=HYST1046;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ACS2L_HUMAN             Reviewed;         689 AA.
AC   Q9NUB1; B3KXL2; B4DJZ3; D3DW48; F5H6F4; F8W7Y1; Q5TF42; Q8IV99;
AC   Q8N234; Q96JI1; Q96JX6; Q9NU28;
DE   RecName: Full=Acetyl-coenzyme A synthetase 2-like, mitochondrial;
DE            EC=6.2.1.1;
DE   AltName: Full=Acetate--CoA ligase 2;
DE   AltName: Full=Acetyl-CoA synthetase 2;
DE            Short=AceCS2;
DE   AltName: Full=Acyl-CoA synthetase short-chain family member 1;
DE   Flags: Precursor;
GN   Name=ACSS1; Synonyms=ACAS2L, KIAA1846;
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019413; P:acetate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006085; P:acetyl-CoA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR   GO; GO:0006069; P:ethanol oxidation; TAS:Reactome.
DR   GO; GO:0019542; P:propionate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ACSA_HUMAN              Reviewed;         701 AA.
AC   Q9NR19; A6NE90; Q5QPH2; Q5QPH3; Q8N238; Q96EL0; Q9NQP7; Q9UJ15;
DE   RecName: Full=Acetyl-coenzyme A synthetase, cytoplasmic;
DE            EC=6.2.1.1;
DE   AltName: Full=Acetate--CoA ligase;
DE   AltName: Full=Acetyl-CoA synthetase;
DE            Short=ACS;
DE            Short=AceCS;
DE   AltName: Full=Acyl-CoA synthetase short-chain family member 2;
DE   AltName: Full=Acyl-activating enzyme;
GN   Name=ACSS2; Synonyms=ACAS2;
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0016208; F:AMP binding; IC:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019413; P:acetate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR   GO; GO:0006069; P:ethanol oxidation; TAS:Reactome.
DR   GO; GO:0008610; P:lipid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0019542; P:propionate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ACSF2_HUMAN             Reviewed;         615 AA.
AC   Q96CM8; Q9H7G2;
DE   RecName: Full=Acyl-CoA synthetase family member 2, mitochondrial;
DE            EC=6.2.1.-;
DE   Flags: Precursor;
GN   Name=ACSF2; ORFNames=UNQ493/PRO1009;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   ACSF3_HUMAN             Reviewed;         576 AA.
AC   Q4G176; A8K4J8; C9JQL6; Q6INA0; Q8N2F7;
DE   RecName: Full=Acyl-CoA synthetase family member 3, mitochondrial;
DE            EC=6.2.1.-;
DE   Flags: Precursor;
GN   Name=ACSF3; ORFNames=PSEC0197;
DR   GO; GO:0016878; F:acid-thiol ligase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0090409; F:malonyl-CoA synthetase activity; IDA:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0090410; P:malonate catabolic process; IDA:UniProtKB.
//
ID   ACSF4_HUMAN             Reviewed;        1098 AA.
AC   Q4L235; A5D8V3; A5PL22; Q63HK2; Q63HR7; Q6IPP8; Q6TFZ6; Q7Z5Y3;
AC   Q96BW4; Q9P064;
DE   RecName: Full=Acyl-CoA synthetase family member 4;
DE            EC=6.2.1.-;
DE   AltName: Full=Aminoadipate-semialdehyde dehydrogenase;
DE   AltName: Full=Protein NRPS998;
GN   Name=AASDH; Synonyms=ACSF4, U26; ORFNames=HSPC318;
DR   GO; GO:0016878; F:acid-thiol ligase activity; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB.
//
ID   ACSL1_HUMAN             Reviewed;         698 AA.
AC   P33121; B7Z452; D3DP57; P41215; Q8N8V7; Q8TA99;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase 1;
DE            EC=6.2.1.3;
DE   AltName: Full=Acyl-CoA synthetase 1;
DE            Short=ACS1;
DE   AltName: Full=Long-chain acyl-CoA synthetase 1;
DE            Short=LACS 1;
DE   AltName: Full=Long-chain acyl-CoA synthetase 2;
DE            Short=LACS 2;
DE   AltName: Full=Long-chain fatty acid-CoA ligase 2;
DE   AltName: Full=Palmitoyl-CoA ligase 1;
DE   AltName: Full=Palmitoyl-CoA ligase 2;
GN   Name=ACSL1; Synonyms=FACL1, FACL2, LACS, LACS1, LACS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0033211; P:adiponectin-activated signaling pathway; IEA:Ensembl.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0043651; P:linoleic acid metabolic process; TAS:Reactome.
DR   GO; GO:0008610; P:lipid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0034201; P:response to oleic acid; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IEA:Ensembl.
//
ID   ACSL4_HUMAN             Reviewed;         711 AA.
AC   O60488; D3DUY2; O60848; O60849;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase 4;
DE            EC=6.2.1.3;
DE   AltName: Full=Long-chain acyl-CoA synthetase 4;
DE            Short=LACS 4;
GN   Name=ACSL4; Synonyms=ACS4, FACL4, LACS4;
DR   GO; GO:0047676; F:arachidonate-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:MGI.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0060996; P:dendritic spine development; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0015908; P:fatty acid transport; IEA:Ensembl.
DR   GO; GO:0008610; P:lipid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; IDA:UniProtKB.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:GOC.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0032307; P:negative regulation of prostaglandin secretion; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0070672; P:response to interleukin-15; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   ACSL3_HUMAN             Reviewed;         720 AA.
AC   O95573; Q60I92; Q8IUM9;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase 3;
DE            EC=6.2.1.3;
DE   AltName: Full=Long-chain acyl-CoA synthetase 3;
DE            Short=LACS 3;
GN   Name=ACSL3; Synonyms=ACS3, FACL3, LACS3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IMP:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.
DR   GO; GO:0042998; P:positive regulation of Golgi to plasma membrane protein transport; IMP:UniProtKB.
DR   GO; GO:2001247; P:positive regulation of phosphatidylcholine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0051047; P:positive regulation of secretion; IMP:UniProtKB.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; IMP:UniProtKB.
//
ID   ACSL5_HUMAN             Reviewed;         683 AA.
AC   Q9ULC5; A6GV77; D3DRB3; Q6UX44; Q9UIU4;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase 5;
DE            EC=6.2.1.3;
DE   AltName: Full=Long-chain acyl-CoA synthetase 5;
DE            Short=LACS 5;
GN   Name=ACSL5; Synonyms=ACS5, FACL5; ORFNames=UNQ633/PRO1250;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:2001236; P:regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   ACSL6_HUMAN             Reviewed;         697 AA.
AC   Q9UKU0; J3KPG3; O94924; O95829; Q108M9; Q108N0; Q4G191; Q86TN7;
DE   RecName: Full=Long-chain-fatty-acid--CoA ligase 6;
DE            EC=6.2.1.3;
DE   AltName: Full=Long-chain acyl-CoA synthetase 6;
DE            Short=LACS 6;
GN   Name=ACSL6; Synonyms=ACS2, FACL6, KIAA0837, LACS5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; NAS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0015908; P:fatty acid transport; IEA:Ensembl.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0010747; P:positive regulation of plasma membrane long-chain fatty acid transport; IEA:Ensembl.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; IEA:Ensembl.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   ACSM1_HUMAN             Reviewed;         577 AA.
AC   Q08AH1; Q08AH2; Q96A20;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM1, mitochondrial;
DE            EC=6.2.1.2;
DE   AltName: Full=Acyl-CoA synthetase medium-chain family member 1;
DE   AltName: Full=Butyrate--CoA ligase 1;
DE   AltName: Full=Butyryl-coenzyme A synthetase 1;
DE   AltName: Full=Lipoate-activating enzyme;
DE   AltName: Full=Middle-chain acyl-CoA synthetase 1;
DE   Flags: Precursor;
GN   Name=ACSM1; Synonyms=BUCS1, LAE, MACS1;
DR   GO; GO:0003996; F:acyl-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0015645; F:fatty acid ligase activity; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0018874; P:benzoate metabolic process; NAS:UniProtKB.
DR   GO; GO:0019605; P:butyrate metabolic process; NAS:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; NAS:BHF-UCL.
DR   GO; GO:0015980; P:energy derivation by oxidation of organic compounds; NAS:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0019395; P:fatty acid oxidation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ACSM3_HUMAN             Reviewed;         586 AA.
AC   Q53FZ2; O60363; Q13732; Q15425; Q7KYM6; Q9BUA2;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM3, mitochondrial;
DE            EC=6.2.1.2;
DE   AltName: Full=Acyl-CoA synthetase medium-chain family member 3;
DE   AltName: Full=Butyrate--CoA ligase 3;
DE   AltName: Full=Butyryl-coenzyme A synthetase 3;
DE   AltName: Full=Middle-chain acyl-CoA synthetase 3;
DE   AltName: Full=Protein SA homolog;
DE   Flags: Precursor;
GN   Name=ACSM3; Synonyms=SAH;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015645; F:fatty acid ligase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042632; P:cholesterol homeostasis; NAS:BHF-UCL.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.
//
ID   ACSM5_HUMAN             Reviewed;         579 AA.
AC   Q6NUN0; Q96AV1; Q96CX8; Q9NWV3;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM5, mitochondrial;
DE            EC=6.2.1.2;
DE   AltName: Full=Acyl-CoA synthetase medium-chain family member 5;
DE   Flags: Precursor;
GN   Name=ACSM5; Synonyms=MACS3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   ACSM4_HUMAN             Reviewed;         580 AA.
AC   P0C7M7; A8MTI6;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM4, mitochondrial;
DE            EC=6.2.1.2;
DE   AltName: Full=Acyl-CoA synthetase medium-chain family member 4;
DE   Flags: Precursor;
GN   Name=ACSM4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004321; F:fatty-acyl-CoA synthase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   ACSM6_HUMAN             Reviewed;         480 AA.
AC   Q6P461; A4FU95; A4IF38; Q5VZX2; Q6ZTX1;
DE   RecName: Full=Acyl-coenzyme A synthetase ACSM6, mitochondrial;
DE            EC=6.2.1.2;
DE   Flags: Precursor;
GN   Name=ACSM6; Synonyms=C10orf129;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047760; F:butyrate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   ACSS3_HUMAN             Reviewed;         686 AA.
AC   Q9H6R3; Q8NC66;
DE   RecName: Full=Acyl-CoA synthetase short-chain family member 3, mitochondrial;
DE            EC=6.2.1.1;
DE   AltName: Full=Acyl-CoA synthetase short-chain family member 3;
DE   Flags: Precursor;
GN   Name=ACSS3;
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   ACTA_HUMAN              Reviewed;         377 AA.
AC   P62736; B2R8A4; P03996; P04108; Q6FI19;
DE   RecName: Full=Actin, aortic smooth muscle;
DE   AltName: Full=Alpha-actin-2;
DE   AltName: Full=Cell growth-inhibiting gene 46 protein;
DE   Flags: Precursor;
GN   Name=ACTA2; Synonyms=ACTSA, ACTVS; ORFNames=GIG46;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0072144; P:glomerular mesangial cell development; IEP:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0014829; P:vascular smooth muscle contraction; IEA:Ensembl.
//
ID   ACTBL_HUMAN             Reviewed;         376 AA.
AC   Q562R1; B2RPJ1; Q562R2; Q562S9; Q562X8;
DE   RecName: Full=Beta-actin-like protein 2;
DE   AltName: Full=Kappa-actin;
GN   Name=ACTBL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   ACTBM_HUMAN             Reviewed;         375 AA.
AC   Q9BYX7; Q562N5;
DE   RecName: Full=Putative beta-actin-like protein 3;
DE   AltName: Full=Kappa-actin;
DE   AltName: Full=POTE ankyrin domain family member K;
GN   Name=POTEKP; Synonyms=ACTBL3; ORFNames=FKSG30;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   ACTB_HUMAN              Reviewed;         375 AA.
AC   P60709; P02570; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34;
AC   Q96HG5;
DE   RecName: Full=Actin, cytoplasmic 1;
DE   AltName: Full=Beta-actin;
DE   Contains:
DE     RecName: Full=Actin, cytoplasmic 1, N-terminally processed;
GN   Name=ACTB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0050998; F:nitric-oxide synthase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
DR   GO; GO:0030957; F:Tat protein binding; IPI:BHF-UCL.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   ACTC_HUMAN              Reviewed;         377 AA.
AC   P68032; P04270;
DE   RecName: Full=Actin, alpha cardiac muscle 1;
DE   AltName: Full=Alpha-cardiac actin;
DE   Flags: Precursor;
GN   Name=ACTC1; Synonyms=ACTC;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; IDA:UniProtKB.
DR   GO; GO:0033275; P:actin-myosin filament sliding; IMP:BHF-UCL.
DR   GO; GO:0031032; P:actomyosin structure organization; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; ISS:UniProtKB.
DR   GO; GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.
DR   GO; GO:0060047; P:heart contraction; IMP:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0030240; P:skeletal muscle thin filament assembly; ISS:UniProtKB.
//
ID   ACTG_HUMAN              Reviewed;         375 AA.
AC   P63261; A8K7C2; P02571; P14104; P99022; Q5U032; Q96E67;
DE   RecName: Full=Actin, cytoplasmic 2;
DE   AltName: Full=Gamma-actin;
DE   Contains:
DE     RecName: Full=Actin, cytoplasmic 2, N-terminally processed;
GN   Name=ACTG1; Synonyms=ACTB, ACTG;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IC:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
//
ID   ACTHR_HUMAN             Reviewed;         297 AA.
AC   Q01718; A8K016; Q3MI45; Q504X6;
DE   RecName: Full=Adrenocorticotropic hormone receptor;
DE            Short=ACTH receptor;
DE            Short=ACTH-R;
DE   AltName: Full=Adrenocorticotropin receptor;
DE   AltName: Full=Melanocortin receptor 2;
DE            Short=MC2-R;
GN   Name=MC2R; Synonyms=ACTHR;
DR   GuidetoPHARMACOLOGY; 283; -.
DR   GO; GO:0004978; F:corticotropin receptor activity; TAS:ProtInc.
DR   GO; GO:0004977; F:melanocortin receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:GOC.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
//
ID   ACTH_HUMAN              Reviewed;         376 AA.
AC   P63267; B2R7E7; B4E315; D6W5H8; E9PG30; P12718; Q504R1; Q6FI22;
DE   RecName: Full=Actin, gamma-enteric smooth muscle;
DE   AltName: Full=Alpha-actin-3;
DE   AltName: Full=Gamma-2-actin;
DE   AltName: Full=Smooth muscle gamma-actin;
DE   Flags: Precursor;
GN   Name=ACTG2; Synonyms=ACTA3, ACTL3, ACTSG;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
//
ID   ACTL8_HUMAN             Reviewed;         366 AA.
AC   Q9H568; Q13104; Q96M75;
DE   RecName: Full=Actin-like protein 8;
DE   AltName: Full=Cancer/testis antigen 57;
DE            Short=CT57;
GN   Name=ACTL8;
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
//
ID   ACTL9_HUMAN             Reviewed;         416 AA.
AC   Q8TC94; A8K893; Q6X960;
DE   RecName: Full=Actin-like protein 9;
GN   Name=ACTL9; Synonyms=ACTL7C; ORFNames=HSD21;
//
ID   ACTN1_HUMAN             Reviewed;         892 AA.
AC   P12814; B3V8S3; B4DHH3; B7TY16; Q1HE25; Q9BTN1;
DE   RecName: Full=Alpha-actinin-1;
DE   AltName: Full=Alpha-actinin cytoskeletal isoform;
DE   AltName: Full=F-actin cross-linking protein;
DE   AltName: Full=Non-muscle alpha-actinin-1;
GN   Name=ACTN1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0005178; F:integrin binding; IDA:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0051271; P:negative regulation of cellular component movement; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
//
ID   ACTN2_HUMAN             Reviewed;         894 AA.
AC   P35609; B1ANE4; B2RCS5; Q86TF4; Q86TI8;
DE   RecName: Full=Alpha-actinin-2;
DE   AltName: Full=Alpha-actinin skeletal muscle isoform 2;
DE   AltName: Full=F-actin cross-linking protein;
GN   Name=ACTN2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:UniProtKB.
DR   GO; GO:0051373; F:FATZ binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005178; F:integrin binding; TAS:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0030375; F:thyroid hormone receptor coactivator activity; IEA:Ensembl.
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0070080; F:titin Z domain binding; IPI:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0030035; P:microspike assembly; IDA:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:1901017; P:negative regulation of potassium ion transmembrane transporter activity; IMP:BHF-UCL.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IMP:BHF-UCL.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IMP:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:1901018; P:positive regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IDA:BHF-UCL.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   ACTN3_HUMAN             Reviewed;         901 AA.
AC   Q08043; A6NP77; Q4KKV2;
DE   RecName: Full=Alpha-actinin-3;
DE   AltName: Full=Alpha-actinin skeletal muscle isoform 3;
DE   AltName: Full=F-actin cross-linking protein;
GN   Name=ACTN3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
//
ID   ACTN4_HUMAN             Reviewed;         911 AA.
AC   O43707; A4K467; D6PXK4; O76048;
DE   RecName: Full=Alpha-actinin-4;
DE   AltName: Full=F-actin cross-linking protein;
DE   AltName: Full=Non-muscle alpha-actinin 4;
GN   Name=ACTN4;
DR   GO; GO:0003779; F:actin binding; TAS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; TAS:UniProtKB.
DR   GO; GO:0001882; F:nucleoside binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0051271; P:negative regulation of cellular component movement; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IDA:UniProtKB.
DR   GO; GO:0048549; P:positive regulation of pinocytosis; IEA:Ensembl.
DR   GO; GO:0032417; P:positive regulation of sodium:proton antiporter activity; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IEA:Ensembl.
//
ID   ACTS_HUMAN              Reviewed;         377 AA.
AC   P68133; P02568; P99020; Q5T8M9;
DE   RecName: Full=Actin, alpha skeletal muscle;
DE   AltName: Full=Alpha-actin-1;
DE   Flags: Precursor;
GN   Name=ACTA1; Synonyms=ACTA;
DR   GO; GO:0043531; F:ADP binding; TAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0017022; F:myosin binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0009991; P:response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0043503; P:skeletal muscle fiber adaptation; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0030240; P:skeletal muscle thin filament assembly; IMP:UniProtKB.
//
ID   ACTT1_HUMAN             Reviewed;         376 AA.
AC   Q8TDG2; Q6X7C1; Q96L10;
DE   RecName: Full=Actin-related protein T1;
DE            Short=ARP-T1;
GN   Name=ACTRT1; Synonyms=ARPT1; ORFNames=HSD27;
//
ID   ACTT2_HUMAN             Reviewed;         377 AA.
AC   Q8TDY3; B1AN52; Q8NHS6; Q8TDG1;
DE   RecName: Full=Actin-related protein T2;
DE            Short=ARP-T2;
DE   AltName: Full=Actin-related protein M2;
GN   Name=ACTRT2; Synonyms=ARPM2;
//
ID   ACTT3_HUMAN             Reviewed;         372 AA.
AC   Q9BYD9; Q96IS0; Q96NJ0;
DE   RecName: Full=Actin-related protein T3;
DE            Short=ARP-T3;
DE   AltName: Full=Actin-related protein M1;
GN   Name=ACTRT3; Synonyms=ARPM1;
//
ID   ACTY_HUMAN              Reviewed;         376 AA.
AC   P42025; D3DVH2; Q53SK5; Q9BRB7;
DE   RecName: Full=Beta-centractin;
DE   AltName: Full=Actin-related protein 1B;
DE            Short=ARP1B;
GN   Name=ACTR1B; Synonyms=CTRN2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
//
ID   ACTZ_HUMAN              Reviewed;         376 AA.
AC   P61163; B2R6B0; P42024;
DE   RecName: Full=Alpha-centractin;
DE            Short=Centractin;
DE   AltName: Full=ARP1;
DE   AltName: Full=Actin-RPV;
DE   AltName: Full=Centrosome-associated actin homolog;
GN   Name=ACTR1A; Synonyms=CTRN1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   ACV1B_HUMAN             Reviewed;         505 AA.
AC   P36896; B7Z5L8; B7Z5W5; Q15479; Q15480; Q15481; Q15482;
DE   RecName: Full=Activin receptor type-1B;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor type IB;
DE            Short=ACTR-IB;
DE   AltName: Full=Activin receptor-like kinase 4;
DE            Short=ALK-4;
DE   AltName: Full=Serine/threonine-protein kinase receptor R2;
DE            Short=SKR2;
DE   Flags: Precursor;
GN   Name=ACVR1B; Synonyms=ACVRLK4, ALK4;
DR   GuidetoPHARMACOLOGY; 1787; -.
DR   GO; GO:0016361; F:activin receptor activity, type I; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0034711; F:inhibin binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0004675; F:transmembrane receptor protein serine/threonine kinase activity; NAS:HGNC.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; NAS:BHF-UCL.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0046545; P:development of primary female sexual characteristics; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:HGNC.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:HGNC.
DR   GO; GO:0038092; P:nodal signaling pathway; IGI:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032927; P:positive regulation of activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:HGNC.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:1901165; P:positive regulation of trophoblast cell migration; IDA:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0007165; P:signal transduction; IDA:HGNC.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; TAS:ProtInc.
//
ID   ACV1C_HUMAN             Reviewed;         493 AA.
AC   Q8NER5; Q4ZFZ8; Q86UL1; Q86UL2; Q8TBG2;
DE   RecName: Full=Activin receptor type-1C;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor type IC;
DE            Short=ACTR-IC;
DE   AltName: Full=Activin receptor-like kinase 7;
DE            Short=ALK-7;
DE   Flags: Precursor;
GN   Name=ACVR1C; Synonyms=ALK7;
DR   GO; GO:0016361; F:activin receptor activity, type I; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019838; F:growth factor binding; IPI:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IC:UniProtKB.
DR   GO; GO:0038100; F:nodal binding; IMP:BHF-UCL.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:1901383; P:negative regulation of chorionic trophoblast cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:1901164; P:negative regulation of trophoblast cell migration; IDA:BHF-UCL.
DR   GO; GO:0038092; P:nodal signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IC:UniProtKB.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   ACVL1_HUMAN             Reviewed;         503 AA.
AC   P37023; A6NGA8;
DE   RecName: Full=Serine/threonine-protein kinase receptor R3;
DE            Short=SKR3;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor-like kinase 1;
DE            Short=ALK-1;
DE   AltName: Full=TGF-B superfamily receptor type I;
DE            Short=TSR-I;
DE   Flags: Precursor;
GN   Name=ACVRL1; Synonyms=ACVRLK1, ALK1;
DR   GuidetoPHARMACOLOGY; 1784; -.
DR   GO; GO:0048185; F:activin binding; IDA:UniProtKB.
DR   GO; GO:0016361; F:activin receptor activity, type I; IDA:MGI.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IPI:UniProtKB.
DR   GO; GO:0005025; F:transforming growth factor beta receptor activity, type I; IEA:Ensembl.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IDA:MGI.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0001525; P:angiogenesis; IMP:HGNC.
DR   GO; GO:0060840; P:artery development; ISS:BHF-UCL.
DR   GO; GO:0008015; P:blood circulation; IMP:HGNC.
DR   GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; TAS:DFLAT.
DR   GO; GO:0001955; P:blood vessel maturation; TAS:DFLAT.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IMP:BHF-UCL.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.
DR   GO; GO:0061154; P:endothelial tube morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001946; P:lymphangiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060836; P:lymphatic endothelial cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IMP:HGNC.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:HGNC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045602; P:negative regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IMP:HGNC.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; TAS:BHF-UCL.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:HGNC.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:HGNC.
DR   GO; GO:0043535; P:regulation of blood vessel endothelial cell migration; TAS:DFLAT.
DR   GO; GO:0006275; P:regulation of DNA replication; TAS:DFLAT.
DR   GO; GO:0001936; P:regulation of endothelial cell proliferation; TAS:DFLAT.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:HGNC.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IDA:HGNC.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0060841; P:venous blood vessel development; ISS:BHF-UCL.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IMP:HGNC.
//
ID   ACVR1_HUMAN             Reviewed;         509 AA.
AC   Q04771;
DE   RecName: Full=Activin receptor type-1;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor type I;
DE            Short=ACTR-I;
DE   AltName: Full=Activin receptor-like kinase 2;
DE            Short=ALK-2;
DE   AltName: Full=Serine/threonine-protein kinase receptor R1;
DE            Short=SKR1;
DE   AltName: Full=TGF-B superfamily receptor type I;
DE            Short=TSR-I;
DE   Flags: Precursor;
GN   Name=ACVR1; Synonyms=ACVRLK2;
DR   GuidetoPHARMACOLOGY; 1785; -.
DR   GO; GO:0048185; F:activin binding; IDA:UniProtKB.
DR   GO; GO:0016361; F:activin receptor activity, type I; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017046; F:peptide hormone binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0004672; F:protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IDA:UniProtKB.
DR   GO; GO:0005025; F:transforming growth factor beta receptor activity, type I; IEA:Ensembl.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0003289; P:atrial septum primum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060923; P:cardiac muscle cell fate commitment; IMP:BHF-UCL.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0061445; P:endocardial cushion cell fate commitment; IMP:BHF-UCL.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:HGNC.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0003183; P:mitral valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IMP:HGNC.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IMP:HGNC.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:2000017; P:positive regulation of determination of dorsal identity; IDA:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0030278; P:regulation of ossification; IMP:UniProtKB.
DR   GO; GO:0048641; P:regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; IEA:Ensembl.
//
ID   ACY1_HUMAN              Reviewed;         408 AA.
AC   Q03154; C9J6I6; C9J9D8; C9JWD4;
DE   RecName: Full=Aminoacylase-1;
DE            Short=ACY-1;
DE            EC=3.5.1.14;
DE   AltName: Full=N-acyl-L-amino-acid amidohydrolase;
GN   Name=ACY1;
DR   GO; GO:0004046; F:aminoacylase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
//
ID   ACY2_HUMAN              Reviewed;         313 AA.
AC   P45381;
DE   RecName: Full=Aspartoacylase;
DE            EC=3.5.1.15;
DE   AltName: Full=Aminoacylase-2;
DE            Short=ACY-2;
GN   Name=ASPA; Synonyms=ACY2, ASP;
DR   GO; GO:0004046; F:aminoacylase activity; TAS:ProtInc.
DR   GO; GO:0019807; F:aspartoacylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006533; P:aspartate catabolic process; TAS:ProtInc.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
//
ID   ACY3_HUMAN              Reviewed;         319 AA.
AC   Q96HD9;
DE   RecName: Full=N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming);
DE            EC=3.5.1.114;
DE   AltName: Full=Acylase III;
DE   AltName: Full=Aminoacylase-3;
DE            Short=ACY-3;
DE   AltName: Full=Aspartoacylase-2;
DE   AltName: Full=Hepatitis C virus core-binding protein 1;
DE            Short=HCBP1;
DE            Short=HCV core-binding protein 1;
GN   Name=ACY3; Synonyms=ASPA2;
DR   GO; GO:0004046; F:aminoacylase activity; ISS:UniProt.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ACYP1_HUMAN             Reviewed;          99 AA.
AC   P07311; A6NDV8; B2R590;
DE   RecName: Full=Acylphosphatase-1;
DE            EC=3.6.1.7;
DE   AltName: Full=Acylphosphatase, erythrocyte isozyme;
DE   AltName: Full=Acylphosphatase, organ-common type isozyme;
DE   AltName: Full=Acylphosphate phosphohydrolase 1;
GN   Name=ACYP1; Synonyms=ACYPE;
DR   GO; GO:0003998; F:acylphosphatase activity; IBA:RefGenome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
//
ID   ACYP2_HUMAN             Reviewed;          99 AA.
AC   P14621;
DE   RecName: Full=Acylphosphatase-2;
DE            EC=3.6.1.7;
DE   AltName: Full=Acylphosphatase, muscle type isozyme;
DE   AltName: Full=Acylphosphate phosphohydrolase 2;
GN   Name=ACYP2; Synonyms=ACYP;
DR   GO; GO:0003998; F:acylphosphatase activity; IBA:RefGenome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
//
ID   ADA10_HUMAN             Reviewed;         748 AA.
AC   O14672; Q10742; Q92650;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10;
DE            Short=ADAM 10;
DE            EC=3.4.24.81;
DE   AltName: Full=CDw156;
DE   AltName: Full=Kuzbanian protein homolog;
DE   AltName: Full=Mammalian disintegrin-metalloprotease;
DE   AltName: CD_antigen=CD156c;
DE   Flags: Precursor;
GN   Name=ADAM10; Synonyms=KUZ, MADM;
DR   GO; GO:0004175; F:endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; NAS:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0051089; P:constitutive protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0042117; P:monocyte activation; IMP:BHF-UCL.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.
DR   GO; GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IMP:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.
//
ID   ADA11_HUMAN             Reviewed;         769 AA.
AC   O75078; Q14808; Q14809; Q14810;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 11;
DE            Short=ADAM 11;
DE   AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein;
DE            Short=MDC;
DE   Flags: Precursor;
GN   Name=ADAM11; Synonyms=MDC;
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.
//
ID   ADA12_HUMAN             Reviewed;         909 AA.
AC   O43184; O60470; Q5JRP0; Q5JRP1; Q6P9E3; Q6UWB0;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 12;
DE            Short=ADAM 12;
DE            EC=3.4.24.-;
DE   AltName: Full=Meltrin-alpha;
DE   Flags: Precursor;
GN   Name=ADAM12; Synonyms=MLTN; ORFNames=UNQ346/PRO545;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007520; P:myoblast fusion; TAS:ProtInc.
//
ID   ADA15_HUMAN             Reviewed;         863 AA.
AC   Q13444; B3KQU5; B4DLB5; E9PN65; Q13493; Q53XQ0; Q5SR68; Q5SR69;
AC   Q6R267; Q71S61; Q71S62; Q71S63; Q71S64; Q71S65; Q71S66; Q71S67;
AC   Q71S68; Q71S69; Q96C78;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 15;
DE            Short=ADAM 15;
DE            EC=3.4.24.-;
DE   AltName: Full=Metalloprotease RGD disintegrin protein;
DE   AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15;
DE            Short=MDC-15;
DE   AltName: Full=Metargidin;
DE   Flags: Precursor;
GN   Name=ADAM15; Synonyms=MDC15;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
//
ID   ADA17_HUMAN             Reviewed;         824 AA.
AC   P78536; O60226;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 17;
DE            Short=ADAM 17;
DE            EC=3.4.24.86;
DE   AltName: Full=Snake venom-like protease;
DE   AltName: Full=TNF-alpha convertase;
DE   AltName: Full=TNF-alpha-converting enzyme;
DE   AltName: CD_antigen=CD156b;
DE   Flags: Precursor;
GN   Name=ADAM17; Synonyms=CSVP, TACE;
DR   GuidetoPHARMACOLOGY; 1662; -.
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005138; F:interleukin-6 receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005112; F:Notch binding; IDA:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0030183; P:B cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:0048870; P:cell motility; ISS:BHF-UCL.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035625; P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0002467; P:germinal center formation; ISS:BHF-UCL.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0032717; P:negative regulation of interleukin-8 production; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002446; P:neutrophil mediated immunity; IC:BHF-UCL.
DR   GO; GO:0007220; P:Notch receptor processing; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; ISS:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IMP:BHF-UCL.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IC:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0033025; P:regulation of mast cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; ISS:BHF-UCL.
DR   GO; GO:0055099; P:response to high density lipoprotein particle; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0048536; P:spleen development; ISS:BHF-UCL.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IEP:BHF-UCL.
//
ID   ADA19_HUMAN             Reviewed;         955 AA.
AC   Q9H013; Q9BZL5; Q9UHP2;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 19;
DE            Short=ADAM 19;
DE            EC=3.4.24.-;
DE   AltName: Full=Meltrin-beta;
DE   AltName: Full=Metalloprotease and disintegrin dendritic antigen marker;
DE            Short=MADDAM;
DE   Flags: Precursor;
GN   Name=ADAM19; Synonyms=MLTNB; ORFNames=FKSG34;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IEA:Ensembl.
//
ID   ADA18_HUMAN             Reviewed;         739 AA.
AC   Q9Y3Q7; B2R9Y0; Q0VAI4; Q6IRW9; Q6UXJ9;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 18;
DE            Short=ADAM 18;
DE   AltName: Full=Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III;
DE            Short=tMDC III;
DE   Flags: Precursor;
GN   Name=ADAM18; Synonyms=TMDC3; ORFNames=UNQ858/PRO1867;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   ADA1A_HUMAN             Reviewed;         466 AA.
AC   P35348; A8K0I3; B0ZBD1; B0ZBD2; B0ZBD4; B0ZBD5; B0ZBD6; B0ZBD8;
AC   B0ZBD9; O60451; Q13675; Q13729; Q4VBM7; Q6RUJ4; Q6RUJ5; Q6RUJ7;
AC   Q6RUJ8; Q6RUJ9; Q96RE8; Q9UD63; Q9UD67;
DE   RecName: Full=Alpha-1A adrenergic receptor;
DE   AltName: Full=Alpha-1A adrenoreceptor;
DE            Short=Alpha-1A adrenoceptor;
DE   AltName: Full=Alpha-1C adrenergic receptor;
DE   AltName: Full=Alpha-adrenergic receptor 1c;
GN   Name=ADRA1A; Synonyms=ADRA1C;
DR   GuidetoPHARMACOLOGY; 22; -.
DR   GO; GO:0004937; F:alpha1-adrenergic receptor activity; NAS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; ISS:BHF-UCL.
DR   GO; GO:0071875; P:adrenergic receptor signaling pathway; ISS:GOC.
DR   GO; GO:0007512; P:adult heart development; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; ISS:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; ISS:BHF-UCL.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0060073; P:micturition; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001985; P:negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:BHF-UCL.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0001994; P:norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0097195; P:pilomotor reflex; IEA:Ensembl.
DR   GO; GO:0045760; P:positive regulation of action potential; ISS:BHF-UCL.
DR   GO; GO:0060452; P:positive regulation of cardiac muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0001996; P:positive regulation of heart rate by epinephrine-norepinephrine; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; ISS:BHF-UCL.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0001997; P:positive regulation of the force of heart contraction by epinephrine-norepinephrine; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; ISS:BHF-UCL.
DR   GO; GO:0009725; P:response to hormone; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006939; P:smooth muscle contraction; TAS:ProtInc.
//
ID   ADA1B_HUMAN             Reviewed;         520 AA.
AC   P35368; B0LPE1;
DE   RecName: Full=Alpha-1B adrenergic receptor;
DE   AltName: Full=Alpha-1B adrenoreceptor;
DE            Short=Alpha-1B adrenoceptor;
GN   Name=ADRA1B;
DR   GuidetoPHARMACOLOGY; 23; -.
DR   GO; GO:0004937; F:alpha1-adrenergic receptor activity; TAS:ProtInc.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071875; P:adrenergic receptor signaling pathway; TAS:GOC.
DR   GO; GO:0007512; P:adult heart development; IEA:Ensembl.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045818; P:negative regulation of glycogen catabolic process; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0045819; P:positive regulation of glycogen catabolic process; IEA:Ensembl.
DR   GO; GO:0001996; P:positive regulation of heart rate by epinephrine-norepinephrine; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0001997; P:positive regulation of the force of heart contraction by epinephrine-norepinephrine; IEA:Ensembl.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IEA:InterPro.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0001987; P:vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   ADA1D_HUMAN             Reviewed;         572 AA.
AC   P25100; Q9NPY0;
DE   RecName: Full=Alpha-1D adrenergic receptor;
DE   AltName: Full=Alpha-1A adrenergic receptor;
DE   AltName: Full=Alpha-1D adrenoreceptor;
DE            Short=Alpha-1D adrenoceptor;
DE   AltName: Full=Alpha-adrenergic receptor 1a;
GN   Name=ADRA1D; Synonyms=ADRA1A;
DR   GuidetoPHARMACOLOGY; 24; -.
DR   GO; GO:0004937; F:alpha1-adrenergic receptor activity; TAS:ProtInc.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071875; P:adrenergic receptor signaling pathway; TAS:GOC.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0001986; P:negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0001994; P:norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   ADA20_HUMAN             Reviewed;         726 AA.
AC   O43506; Q6GTZ1; Q9UKJ9;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 20;
DE            Short=ADAM 20;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAM20;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ADA21_HUMAN             Reviewed;         722 AA.
AC   Q9UKJ8; O43507; Q2VPC6; Q32MR0;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 21;
DE            Short=ADAM 21;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAM21;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ADA22_HUMAN             Reviewed;         906 AA.
AC   Q9P0K1; O75075; O75076; Q9P0K2; Q9UIA1; Q9UKK2;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 22;
DE            Short=ADAM 22;
DE   AltName: Full=Metalloproteinase-disintegrin ADAM22-3;
DE   AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2;
DE   Flags: Precursor;
GN   Name=ADAM22; Synonyms=MDC2;
DR   GO; GO:0005178; F:integrin binding; NAS:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; NAS:UniProtKB.
//
ID   ADA23_HUMAN             Reviewed;         832 AA.
AC   O75077; A2RU59;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 23;
DE            Short=ADAM 23;
DE   AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3;
DE            Short=MDC-3;
DE   Flags: Precursor;
GN   Name=ADAM23; Synonyms=MDC3;
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:DFLAT.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
//
ID   ADA28_HUMAN             Reviewed;         775 AA.
AC   Q9UKQ2; B2RMV5; Q9Y339; Q9Y3S0;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 28;
DE            Short=ADAM 28;
DE            EC=3.4.24.-;
DE   AltName: Full=Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II;
DE            Short=eMDC II;
DE   AltName: Full=Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L;
DE            Short=MDC-L;
DE   Flags: Precursor;
GN   Name=ADAM28; Synonyms=ADAM23, MDCL;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   ADA29_HUMAN             Reviewed;         820 AA.
AC   Q9UKF5; Q4W5F3; Q9UHP1; Q9UKF3; Q9UKF4;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 29;
DE            Short=ADAM 29;
DE   AltName: Full=Cancer/testis antigen 73;
DE            Short=CT73;
DE   Flags: Precursor;
GN   Name=ADAM29;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   ADA2A_HUMAN             Reviewed;         450 AA.
AC   P08913; B0LPF6; Q2I8G2; Q2XN99; Q86TH8; Q9BZK1;
DE   RecName: Full=Alpha-2A adrenergic receptor;
DE   AltName: Full=Alpha-2 adrenergic receptor subtype C10;
DE   AltName: Full=Alpha-2A adrenoreceptor;
DE            Short=Alpha-2A adrenoceptor;
DE            Short=Alpha-2AAR;
GN   Name=ADRA2A; Synonyms=ADRA2R, ADRAR;
DR   GuidetoPHARMACOLOGY; 25; -.
DR   GO; GO:0031692; F:alpha-1B adrenergic receptor binding; ISS:BHF-UCL.
DR   GO; GO:0031696; F:alpha-2C adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004938; F:alpha2-adrenergic receptor activity; IDA:BHF-UCL.
DR   GO; GO:0051379; F:epinephrine binding; IDA:BHF-UCL.
DR   GO; GO:0032795; F:heterotrimeric G-protein binding; IDA:BHF-UCL.
DR   GO; GO:0051380; F:norepinephrine binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0031996; F:thioesterase binding; IPI:BHF-UCL.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0071883; P:activation of MAPK activity by adrenergic receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0071881; P:adenylate cyclase-inhibiting adrenergic receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IGI:BHF-UCL.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0035625; P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042596; P:fear response; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0050892; P:intestinal absorption; TAS:BHF-UCL.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; ISS:BHF-UCL.
DR   GO; GO:0071878; P:negative regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:1901020; P:negative regulation of calcium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; ISS:BHF-UCL.
DR   GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IC:BHF-UCL.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032811; P:negative regulation of epinephrine secretion; NAS:BHF-UCL.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IGI:BHF-UCL.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; NAS:BHF-UCL.
DR   GO; GO:0070473; P:negative regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0071882; P:phospholipase C-activating adrenergic receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:BHF-UCL.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; ISS:BHF-UCL.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0090303; P:positive regulation of wound healing; IMP:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050955; P:thermoception; IEA:Ensembl.
//
ID   ADA2B_HUMAN             Reviewed;         447 AA.
AC   P18089; Q4TUH9; Q53RF2; Q9BZK0;
DE   RecName: Full=Alpha-2B adrenergic receptor;
DE   AltName: Full=Alpha-2 adrenergic receptor subtype C2;
DE   AltName: Full=Alpha-2B adrenoreceptor;
DE            Short=Alpha-2B adrenoceptor;
DE            Short=Alpha-2BAR;
GN   Name=ADRA2B; Synonyms=ADRA2L1, ADRA2RL1;
DR   GuidetoPHARMACOLOGY; 26; -.
DR   GO; GO:0004938; F:alpha2-adrenergic receptor activity; IDA:BHF-UCL.
DR   GO; GO:0051379; F:epinephrine binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0071883; P:activation of MAPK activity by adrenergic receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0035625; P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0032811; P:negative regulation of epinephrine secretion; NAS:BHF-UCL.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; NAS:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IDA:BHF-UCL.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0003056; P:regulation of vascular smooth muscle contraction; IEA:Ensembl.
//
ID   ADA2C_HUMAN             Reviewed;         462 AA.
AC   P18825; P35369; Q9HB49;
DE   RecName: Full=Alpha-2C adrenergic receptor;
DE   AltName: Full=Alpha-2 adrenergic receptor subtype C4;
DE   AltName: Full=Alpha-2C adrenoreceptor;
DE            Short=Alpha-2C adrenoceptor;
DE            Short=Alpha-2CAR;
GN   Name=ADRA2C; Synonyms=ADRA2L2, ADRA2RL2;
DR   GuidetoPHARMACOLOGY; 27; -.
DR   GO; GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004938; F:alpha2-adrenergic receptor activity; IDA:BHF-UCL.
DR   GO; GO:0051379; F:epinephrine binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0071883; P:activation of MAPK activity by adrenergic receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0035625; P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0032811; P:negative regulation of epinephrine secretion; NAS:BHF-UCL.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; NAS:BHF-UCL.
DR   GO; GO:0070473; P:negative regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IDA:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ADA30_HUMAN             Reviewed;         790 AA.
AC   Q9UKF2; A8K8W8; Q5T3X6; Q9UKF1;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 30;
DE            Short=ADAM 30;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAM30; ORFNames=UNQ2509/PRO5997;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ADA32_HUMAN             Reviewed;         787 AA.
AC   Q8TC27; Q8TC42;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 32;
DE            Short=ADAM 32;
DE   Flags: Precursor;
GN   Name=ADAM32; ORFNames=UNQ5982/PRO21340;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ADA33_HUMAN             Reviewed;         813 AA.
AC   Q9BZ11; A0A1K6; Q5JT75; Q5JT76; Q8N0W6;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 33;
DE            Short=ADAM 33;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAM33; Synonyms=C20orf153; ORFNames=UNQ873/PRO1891;
DR   GO; GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   ADAD1_HUMAN             Reviewed;         576 AA.
AC   Q96M93; A6NKN4; B7WPB0; D3DNX2; Q8IWG6; Q8NA06;
DE   RecName: Full=Adenosine deaminase domain-containing protein 1;
DE   AltName: Full=Testis nuclear RNA-binding protein;
GN   Name=ADAD1; Synonyms=TENR;
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   ADAD2_HUMAN             Reviewed;         583 AA.
AC   Q8NCV1; B2RCL6; Q8NA94;
DE   RecName: Full=Adenosine deaminase domain-containing protein 2;
DE   AltName: Full=Testis nuclear RNA-binding protein-like;
GN   Name=ADAD2; Synonyms=TENRL;
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   ADAL_HUMAN              Reviewed;         355 AA.
AC   Q6DHV7; A6NHZ3; B4DQM8;
DE   RecName: Full=Adenosine deaminase-like protein;
DE            EC=3.5.4.-;
GN   Name=ADAL;
DR   GO; GO:0004000; F:adenosine deaminase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006154; P:adenosine catabolic process; IBA:RefGenome.
DR   GO; GO:0017144; P:drug metabolic process; TAS:Reactome.
DR   GO; GO:0046103; P:inosine biosynthetic process; IBA:RefGenome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ADAM2_HUMAN             Reviewed;         735 AA.
AC   Q99965; P78326; Q9UQQ8;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 2;
DE            Short=ADAM 2;
DE   AltName: Full=Cancer/testis antigen 15;
DE            Short=CT15;
DE   AltName: Full=Fertilin subunit beta;
DE   AltName: Full=PH-30;
DE            Short=PH30;
DE   AltName: Full=PH30-beta;
DE   Flags: Precursor;
GN   Name=ADAM2; Synonyms=FTNB;
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; TAS:ProtInc.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   ADAM5_HUMAN             Reviewed;         412 AA.
AC   Q6NVV9; A8MW71; Q4G196;
DE   RecName: Full=Putative disintegrin and metalloproteinase domain-containing protein 5;
DE   AltName: Full=Putative transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II;
DE            Short=tMDC II;
GN   Name=ADAM5; Synonyms=ADAM5P, TMDC2;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ADAM7_HUMAN             Reviewed;         754 AA.
AC   Q9H2U9; A8K8X7; O75959;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 7;
DE            Short=ADAM 7;
DE   AltName: Full=Sperm maturation-related glycoprotein GP-83;
DE   Flags: Precursor;
GN   Name=ADAM7; Synonyms=GP83;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ADAM8_HUMAN             Reviewed;         824 AA.
AC   P78325; B4DVM6; H0YL36; H0YLR0; H0YN39;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 8;
DE            Short=ADAM 8;
DE            EC=3.4.24.-;
DE   AltName: Full=Cell surface antigen MS2;
DE   AltName: CD_antigen=CD156a;
DE   Flags: Precursor;
GN   Name=ADAM8; Synonyms=MS2;
DR   GO; GO:0005509; F:calcium ion binding; ISS:BHF-UCL.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; TAS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:BHF-UCL.
DR   GO; GO:0035419; P:activation of MAPK activity involved in innate immune response; ISS:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0000902; P:cell morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0002523; P:leukocyte migration involved in inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0045780; P:positive regulation of bone resorption; ISS:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; ISS:BHF-UCL.
DR   GO; GO:2000418; P:positive regulation of eosinophil migration; ISS:BHF-UCL.
DR   GO; GO:2000415; P:positive regulation of fibronectin-dependent thymocyte migration; ISS:BHF-UCL.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:2000391; P:positive regulation of neutrophil extravasation; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:BHF-UCL.
DR   GO; GO:0010954; P:positive regulation of protein processing; NAS:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IC:BHF-UCL.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0070245; P:positive regulation of thymocyte apoptotic process; ISS:BHF-UCL.
DR   GO; GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; ISS:BHF-UCL.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IDA:BHF-UCL.
//
ID   ADAM9_HUMAN             Reviewed;         819 AA.
AC   Q13443; B7ZLN7; Q10718; Q8NFM6;
DE   RecName: Full=Disintegrin and metalloproteinase domain-containing protein 9;
DE            Short=ADAM 9;
DE            EC=3.4.24.-;
DE   AltName: Full=Cellular disintegrin-related protein;
DE   AltName: Full=Meltrin-gamma;
DE   AltName: Full=Metalloprotease/disintegrin/cysteine-rich protein 9;
DE   AltName: Full=Myeloma cell metalloproteinase;
DE   Flags: Precursor;
GN   Name=ADAM9; Synonyms=KIAA0021, MCMP, MDC9, MLTNG;
DR   GO; GO:0005518; F:collagen binding; IMP:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IDA:BHF-UCL.
DR   GO; GO:0043236; F:laminin binding; IMP:BHF-UCL.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008237; F:metallopeptidase activity; IMP:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IMP:BHF-UCL.
DR   GO; GO:0033631; P:cell-cell adhesion mediated by integrin; IEP:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEP:BHF-UCL.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0042117; P:monocyte activation; IMP:BHF-UCL.
DR   GO; GO:0051088; P:PMA-inducible membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IMP:BHF-UCL.
DR   GO; GO:0051549; P:positive regulation of keratinocyte migration; IMP:BHF-UCL.
DR   GO; GO:0034241; P:positive regulation of macrophage fusion; IMP:BHF-UCL.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; ISS:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IMP:BHF-UCL.
DR   GO; GO:0051384; P:response to glucocorticoid; ISS:BHF-UCL.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IMP:BHF-UCL.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IMP:BHF-UCL.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
//
ID   ADAP1_HUMAN             Reviewed;         374 AA.
AC   O75689; A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4;
DE   RecName: Full=Arf-GAP with dual PH domain-containing protein 1;
DE   AltName: Full=Centaurin-alpha-1;
DE            Short=Cnt-a1;
DE   AltName: Full=Putative MAPK-activating protein PM25;
GN   Name=ADAP1; Synonyms=CENTA1;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; TAS:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IMP:UniProtKB.
//
ID   ADAP2_HUMAN             Reviewed;         381 AA.
AC   Q9NPF8; Q8N4Q6; Q96SD5;
DE   RecName: Full=Arf-GAP with dual PH domain-containing protein 2;
DE   AltName: Full=Centaurin-alpha-2;
DE            Short=Cnt-a2;
GN   Name=ADAP2; Synonyms=CENTA2;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; IEP:UniProtKB.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   ADAS1_HUMAN             Reviewed;         147 AA.
AC   A8MUL3;
DE   RecName: Full=Putative uncharacterized protein ADARB2-AS1;
DE   AltName: Full=ADARB2 antisense RNA 1;
DE   AltName: Full=ADARB2 antisense gene protein 1;
GN   Name=ADARB2-AS1; Synonyms=C10orf109, NCRNA00168;
//
ID   ADAS_HUMAN              Reviewed;         658 AA.
AC   O00116; A5D8U9; Q2TU35;
DE   RecName: Full=Alkyldihydroxyacetonephosphate synthase, peroxisomal;
DE            Short=Alkyl-DHAP synthase;
DE            EC=2.5.1.26;
DE   AltName: Full=Aging-associated gene 5 protein;
DE   AltName: Full=Alkylglycerone-phosphate synthase;
DE   Flags: Precursor;
GN   Name=AGPS; ORFNames=AAG5;
DR   GO; GO:0008609; F:alkylglycerone-phosphate synthase activity; IDA:UniProtKB.
DR   GO; GO:0071949; F:FAD binding; ISS:UniProtKB.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008611; P:ether lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0008610; P:lipid biosynthetic process; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ADAT1_HUMAN             Reviewed;         502 AA.
AC   Q9BUB4; Q9NVB7; Q9UNG3;
DE   RecName: Full=tRNA-specific adenosine deaminase 1;
DE            Short=hADAT1;
DE            EC=3.5.4.34;
DE   AltName: Full=tRNA-specific adenosine-37 deaminase;
GN   Name=ADAT1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IMP:UniProtKB.
DR   GO; GO:0008251; F:tRNA-specific adenosine deaminase activity; IMP:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IMP:UniProtKB.
//
ID   ADAT2_HUMAN             Reviewed;         191 AA.
AC   Q7Z6V5; A6NL12; B3KWY3; Q7Z327; Q8IY39;
DE   RecName: Full=tRNA-specific adenosine deaminase 2;
DE            EC=3.5.4.-;
DE   AltName: Full=Deaminase domain-containing protein 1;
DE   AltName: Full=tRNA-specific adenosine-34 deaminase subunit ADAT2;
GN   Name=ADAT2; Synonyms=DEADC1;
DR   GO; GO:0008251; F:tRNA-specific adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002100; P:tRNA wobble adenosine to inosine editing; IEA:InterPro.
//
ID   ADAT3_HUMAN             Reviewed;         351 AA.
AC   Q96EY9;
DE   RecName: Full=Probable inactive tRNA-specific adenosine deaminase-like protein 3;
DE   AltName: Full=tRNA-specific adenosine-34 deaminase subunit ADAT3;
GN   Name=ADAT3; Synonyms=TAD3;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   ADA_HUMAN               Reviewed;         363 AA.
AC   P00813; Q53F92; Q6LA59;
DE   RecName: Full=Adenosine deaminase;
DE            EC=3.5.4.4;
DE   AltName: Full=Adenosine aminohydrolase;
GN   Name=ADA; Synonyms=ADA1;
DR   GuidetoPHARMACOLOGY; 1230; -.
DR   GO; GO:0004000; F:adenosine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001883; F:purine nucleoside binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IMP:UniProtKB.
DR   GO; GO:0006154; P:adenosine catabolic process; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0046061; P:dATP catabolic process; IEA:Ensembl.
DR   GO; GO:0006157; P:deoxyadenosine catabolic process; IEA:Ensembl.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEA:Ensembl.
DR   GO; GO:0002314; P:germinal center B cell differentiation; IEA:Ensembl.
DR   GO; GO:0001821; P:histamine secretion; IEA:Ensembl.
DR   GO; GO:0043103; P:hypoxanthine salvage; IBA:RefGenome.
DR   GO; GO:0046103; P:inosine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0060169; P:negative regulation of adenosine receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042323; P:negative regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0002686; P:negative regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0002906; P:negative regulation of mature B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0070256; P:negative regulation of mucus secretion; IEA:Ensembl.
DR   GO; GO:0060407; P:negative regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0002636; P:positive regulation of germinal center formation; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0032261; P:purine nucleotide salvage; IMP:UniProtKB.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0033632; P:regulation of cell-cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; IDA:UniProtKB.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0046111; P:xanthine biosynthetic process; IEA:Ensembl.
//
ID   ADCK1_HUMAN             Reviewed;         530 AA.
AC   Q86TW2; B3KUD5; Q6PD65; Q9UIE6;
DE   RecName: Full=Uncharacterized aarF domain-containing protein kinase 1;
DE            EC=2.7.11.-;
DE   Flags: Precursor;
GN   Name=ADCK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ADCK2_HUMAN             Reviewed;         626 AA.
AC   Q7Z695; Q96CN6; Q9Y6T5;
DE   RecName: Full=Uncharacterized aarF domain-containing protein kinase 2;
DE            EC=2.7.11.-;
GN   Name=ADCK2; Synonyms=AARF;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ADCK3_HUMAN             Reviewed;         647 AA.
AC   Q8NI60; Q5T7A5; Q63HK0; Q8NCJ6; Q9HBQ1; Q9NQ67;
DE   RecName: Full=Chaperone activity of bc1 complex-like, mitochondrial;
DE            Short=Chaperone-ABC1-like;
DE            EC=2.7.11.-;
DE   AltName: Full=aarF domain-containing protein kinase 3;
DE   Flags: Precursor;
GN   Name=ADCK3; Synonyms=CABC1; ORFNames=PP265;
DR   GuidetoPHARMACOLOGY; 1927; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
//
ID   ADCK5_HUMAN             Reviewed;         580 AA.
AC   Q3MIX3; B3KS46; Q5U4P1; Q6P2S4; Q8N5V3;
DE   RecName: Full=Uncharacterized aarF domain-containing protein kinase 5;
DE            EC=2.7.11.-;
GN   Name=ADCK5;
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ADCL2_HUMAN             Reviewed;         401 AA.
AC   Q6P093; Q5HYJ4;
DE   RecName: Full=Arylacetamide deacetylase-like 2;
DE            EC=3.1.1.-;
DE   Flags: Precursor;
GN   Name=AADACL2;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
//
ID   ADCK4_HUMAN             Reviewed;         544 AA.
AC   Q96D53; Q8TAJ1; Q9HA52;
DE   RecName: Full=AarF domain-containing protein kinase 4;
DE            EC=2.7.11.-;
GN   Name=ADCK4;
DR   GuidetoPHARMACOLOGY; 1928; -.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ADCL3_HUMAN             Reviewed;         350 AA.
AC   Q5VUY0; B3KXR9; Q5VUY1;
DE   RecName: Full=Arylacetamide deacetylase-like 3;
DE            EC=3.1.1.-;
GN   Name=AADACL3;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   ADCL4_HUMAN             Reviewed;         407 AA.
AC   Q5VUY2;
DE   RecName: Full=Arylacetamide deacetylase-like 4;
DE            EC=3.1.1.-;
GN   Name=AADACL4;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
//
ID   ADCY1_HUMAN             Reviewed;        1119 AA.
AC   Q08828; A4D2L8; Q75MI1;
DE   RecName: Full=Adenylate cyclase type 1;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 1;
DE   AltName: Full=Adenylate cyclase type I;
DE   AltName: Full=Adenylyl cyclase 1;
DE   AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase;
GN   Name=ADCY1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008294; F:calcium- and calmodulin-responsive adenylate cyclase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY2_HUMAN             Reviewed;        1091 AA.
AC   Q08462; Q2NKL8; Q9UDB2; Q9UPU2;
DE   RecName: Full=Adenylate cyclase type 2;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 2;
DE   AltName: Full=Adenylate cyclase type II;
DE   AltName: Full=Adenylyl cyclase 2;
GN   Name=ADCY2; Synonyms=KIAA1060;
DR   GO; GO:0004016; F:adenylate cyclase activity; NAS:UniProtKB.
DR   GO; GO:0008179; F:adenylate cyclase binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008294; F:calcium- and calmodulin-responsive adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0006171; P:cAMP biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY3_HUMAN             Reviewed;        1144 AA.
AC   O60266; Q53T54; Q9UDB1;
DE   RecName: Full=Adenylate cyclase type 3;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 3;
DE   AltName: Full=Adenylate cyclase type III;
DE            Short=AC-III;
DE   AltName: Full=Adenylate cyclase, olfactive type;
DE   AltName: Full=Adenylyl cyclase 3;
DE            Short=AC3;
GN   Name=ADCY3; Synonyms=KIAA0511;
DR   GO; GO:0004016; F:adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY4_HUMAN             Reviewed;        1077 AA.
AC   Q8NFM4; B3KV74; D3DS75; Q17R40; Q96ML7;
DE   RecName: Full=Adenylate cyclase type 4;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 4;
DE   AltName: Full=Adenylate cyclase type IV;
DE   AltName: Full=Adenylyl cyclase 4;
GN   Name=ADCY4;
DR   GO; GO:0004016; F:adenylate cyclase activity; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006171; P:cAMP biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY5_HUMAN             Reviewed;        1261 AA.
AC   O95622; B7Z8A6; Q7RTV7; Q8NFM3;
DE   RecName: Full=Adenylate cyclase type 5;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 5;
DE   AltName: Full=Adenylate cyclase type V;
DE   AltName: Full=Adenylyl cyclase 5;
GN   Name=ADCY5;
DR   GuidetoPHARMACOLOGY; 1282; -.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008179; F:adenylate cyclase binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0001973; P:adenosine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007195; P:adenylate cyclase-inhibiting dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY6_HUMAN             Reviewed;        1168 AA.
AC   O43306; Q9NR75; Q9UDB0;
DE   RecName: Full=Adenylate cyclase type 6;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 6;
DE   AltName: Full=Adenylate cyclase type VI;
DE   AltName: Full=Adenylyl cyclase 6;
DE   AltName: Full=Ca(2+)-inhibitable adenylyl cyclase;
GN   Name=ADCY6; Synonyms=KIAA0422;
DR   GO; GO:0004016; F:adenylate cyclase activity; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; IDA:BHF-UCL.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:ParkinsonsUK-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY7_HUMAN             Reviewed;        1080 AA.
AC   P51828; A0AVA6;
DE   RecName: Full=Adenylate cyclase type 7;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 7;
DE   AltName: Full=Adenylate cyclase type VII;
DE   AltName: Full=Adenylyl cyclase 7;
GN   Name=ADCY7; Synonyms=KIAA0037;
DR   GO; GO:0004016; F:adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0071361; P:cellular response to ethanol; IDA:UniProtKB.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY8_HUMAN             Reviewed;        1251 AA.
AC   P40145;
DE   RecName: Full=Adenylate cyclase type 8;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 8;
DE   AltName: Full=Adenylate cyclase type VIII;
DE   AltName: Full=Adenylyl cyclase 8;
DE            Short=AC8;
DE   AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase;
GN   Name=ADCY8;
DR   GO; GO:0004016; F:adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008294; F:calcium- and calmodulin-responsive adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007611; P:learning or memory; TAS:ProtInc.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCY9_HUMAN             Reviewed;        1353 AA.
AC   O60503; A7E2V5; A7E2X2; D3DUD1; O60273; Q4ZHT9; Q4ZIR5; Q9BWT4;
AC   Q9UGP2;
DE   RecName: Full=Adenylate cyclase type 9;
DE            EC=4.6.1.1;
DE   AltName: Full=ATP pyrophosphate-lyase 9;
DE   AltName: Full=Adenylate cyclase type IX;
DE   AltName: Full=Adenylyl cyclase 9;
GN   Name=ADCY9; Synonyms=KIAA0520;
DR   GO; GO:0004016; F:adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   ADCYA_HUMAN             Reviewed;        1610 AA.
AC   Q96PN6; B4DZF0; F5GWS5; O95558; Q5R329; Q5R330; Q8WXV4; Q9NNX0;
DE   RecName: Full=Adenylate cyclase type 10;
DE            EC=4.6.1.1;
DE   AltName: Full=AH-related protein;
DE   AltName: Full=Adenylate cyclase homolog;
DE   AltName: Full=Germ cell soluble adenylyl cyclase;
DE            Short=hsAC;
DE            Short=sAC;
DE   AltName: Full=Testicular soluble adenylyl cyclase;
GN   Name=ADCY10; Synonyms=SAC;
DR   GO; GO:0004016; F:adenylate cyclase activity; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0006171; P:cAMP biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:InterPro.
//
ID   ADC_HUMAN               Reviewed;         460 AA.
AC   Q96A70; B2RDU5; D3DPQ9; Q5TIF4; Q5TIF5; Q5TIF6; Q8TF56; Q96L54;
AC   Q96L55; Q96L56; Q96L57; Q96MD9;
DE   RecName: Full=Arginine decarboxylase;
DE            Short=ADC;
DE            Short=ARGDC;
DE            EC=4.1.1.19;
DE   AltName: Full=ODC-paralogue;
DE            Short=ODC-p;
DE   AltName: Full=Ornithine decarboxylase-like protein;
GN   Name=ADC; Synonyms=KIAA1945, ODCP;
DR   GO; GO:0008792; F:arginine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042978; F:ornithine decarboxylase activator activity; IEA:Ensembl.
DR   GO; GO:0097055; P:agmatine biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006591; P:ornithine metabolic process; IEA:Ensembl.
DR   GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   ADDA_HUMAN              Reviewed;         737 AA.
AC   P35611; A2A3P0; D3DVR3; D3DVR4; D3DVR5; Q13734; Q14729; Q16156;
AC   Q86XM2; Q9UJB6;
DE   RecName: Full=Alpha-adducin;
DE   AltName: Full=Erythrocyte adducin subunit alpha;
GN   Name=ADD1; Synonyms=ADDA;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0051015; F:actin filament binding; IDA:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0030507; F:spectrin binding; IDA:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IC:BHF-UCL.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:BHF-UCL.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0006884; P:cell volume homeostasis; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0020027; P:hemoglobin metabolic process; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
//
ID   ADDB_HUMAN              Reviewed;         726 AA.
AC   P35612; A8K4P2; B4DM17; D6W5G7; D6W5G8; Q13482; Q16412; Q59G82;
AC   Q5U5P4; Q6P0P2; Q6PGQ4; Q7Z688; Q7Z689; Q7Z690; Q7Z691;
DE   RecName: Full=Beta-adducin;
DE   AltName: Full=Erythrocyte adducin subunit beta;
GN   Name=ADD2; Synonyms=ADDB;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0051015; F:actin filament binding; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0030507; F:spectrin binding; IDA:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IEA:Ensembl.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IC:BHF-UCL.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:BHF-UCL.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
//
ID   ADDG_HUMAN              Reviewed;         706 AA.
AC   Q9UEY8; D3DRA8; O43243; Q5VU09; Q92773; Q9UEY7;
DE   RecName: Full=Gamma-adducin;
DE   AltName: Full=Adducin-like protein 70;
GN   Name=ADD3; Synonyms=ADDL;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
//
ID   ADEC1_HUMAN             Reviewed;         470 AA.
AC   O15204; B7ZAK5;
DE   RecName: Full=ADAM DEC1;
DE            EC=3.4.24.-;
DE   AltName: Full=A disintegrin and metalloproteinase domain-like protein decysin-1;
DE            Short=ADAM-like protein decysin-1;
DE   Flags: Precursor;
GN   Name=ADAMDEC1;
DR   GO; GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; NAS:UniProtKB.
//
ID   ADGB_HUMAN              Reviewed;        1667 AA.
AC   Q8N7X0; Q5T402; Q5T904; Q5T905;
DE   RecName: Full=Androglobin;
DE   AltName: Full=Calpain-7-like protein;
GN   Name=ADGB; Synonyms=C6orf103, CAPN7L;
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0015671; P:oxygen transport; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   ADH1A_HUMAN             Reviewed;         375 AA.
AC   P07327; A8K3E3; Q17R68;
DE   RecName: Full=Alcohol dehydrogenase 1A;
DE            EC=1.1.1.1;
DE   AltName: Full=Alcohol dehydrogenase subunit alpha;
GN   Name=ADH1A; Synonyms=ADH1;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; TAS:Reactome.
DR   GO; GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006066; P:alcohol metabolic process; NAS:UniProtKB.
DR   GO; GO:0017144; P:drug metabolic process; TAS:Reactome.
DR   GO; GO:0006069; P:ethanol oxidation; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ADH1B_HUMAN             Reviewed;         375 AA.
AC   P00325; A8MYN5; B4DRS9; B4DVC3; Q13711; Q4ZGI9; Q96KI7;
DE   RecName: Full=Alcohol dehydrogenase 1B;
DE            EC=1.1.1.1;
DE   AltName: Full=Alcohol dehydrogenase subunit beta;
GN   Name=ADH1B; Synonyms=ADH2;
DR   GO; GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006069; P:ethanol oxidation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ADH1G_HUMAN             Reviewed;         375 AA.
AC   P00326; Q4PJ18; Q5WRV0; Q6LBW4; Q6NWV0; Q6NZA7;
DE   RecName: Full=Alcohol dehydrogenase 1C;
DE            EC=1.1.1.1;
DE   AltName: Full=Alcohol dehydrogenase subunit gamma;
GN   Name=ADH1C; Synonyms=ADH3;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006069; P:ethanol oxidation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ADH4_HUMAN              Reviewed;         380 AA.
AC   P08319; A8K470; B4DIE7; C9J4A9; Q8TCD7;
DE   RecName: Full=Alcohol dehydrogenase 4;
DE            EC=1.1.1.1;
DE   AltName: Full=Alcohol dehydrogenase class II pi chain;
GN   Name=ADH4;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IDA:UniProtKB.
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:Ensembl.
DR   GO; GO:0005503; F:all-trans retinal binding; IDA:UniProtKB.
DR   GO; GO:0019115; F:benzaldehyde dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0035276; F:ethanol binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IDA:UniProtKB.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; ISS:UniProtKB.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IDA:UniProtKB.
DR   GO; GO:0019841; F:retinol binding; IDA:UniProtKB.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0046164; P:alcohol catabolic process; ISS:UniProtKB.
DR   GO; GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IDA:UniProtKB.
DR   GO; GO:0006069; P:ethanol oxidation; IDA:UniProtKB.
DR   GO; GO:1901661; P:quinone metabolic process; ISS:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; IDA:UniProtKB.
DR   GO; GO:0042572; P:retinol metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ADH6_HUMAN              Reviewed;         368 AA.
AC   P28332; B3KS45; Q58F53;
DE   RecName: Full=Alcohol dehydrogenase 6;
DE            EC=1.1.1.1;
GN   Name=ADH6;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IEA:InterPro.
DR   GO; GO:0035276; F:ethanol binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006069; P:ethanol oxidation; IDA:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ADH7_HUMAN              Reviewed;         386 AA.
AC   P40394; A2RRB6; A8MVN9; B2R760; B4DWV6; Q13713;
DE   RecName: Full=Alcohol dehydrogenase class 4 mu/sigma chain;
DE            EC=1.1.1.1;
DE   AltName: Full=Alcohol dehydrogenase class IV mu/sigma chain;
DE   AltName: Full=Gastric alcohol dehydrogenase;
DE   AltName: Full=Retinol dehydrogenase;
GN   Name=ADH7;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; TAS:UniProtKB.
DR   GO; GO:0004024; F:alcohol dehydrogenase activity, zinc-dependent; IDA:UniProtKB.
DR   GO; GO:0004031; F:aldehyde oxidase activity; IDA:UniProtKB.
DR   GO; GO:0035276; F:ethanol binding; IDA:UniProtKB.
DR   GO; GO:0048019; F:receptor antagonist activity; IDA:UniProtKB.
DR   GO; GO:0019841; F:retinol binding; IDA:UniProtKB.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006068; P:ethanol catabolic process; IEA:Ensembl.
DR   GO; GO:0006069; P:ethanol oxidation; IDA:UniProtKB.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; IDA:GOC.
DR   GO; GO:0010430; P:fatty acid omega-oxidation; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IDA:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; IDA:UniProtKB.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ADHX_HUMAN              Reviewed;         374 AA.
AC   P11766; Q6FHR2;
DE   RecName: Full=Alcohol dehydrogenase class-3;
DE            EC=1.1.1.1;
DE   AltName: Full=Alcohol dehydrogenase 5;
DE   AltName: Full=Alcohol dehydrogenase class chi chain;
DE   AltName: Full=Alcohol dehydrogenase class-III;
DE   AltName: Full=Glutathione-dependent formaldehyde dehydrogenase;
DE            Short=FALDH;
DE            Short=FDH;
DE            Short=GSH-FDH;
DE            EC=1.1.1.-;
DE   AltName: Full=S-(hydroxymethyl)glutathione dehydrogenase;
DE            EC=1.1.1.284;
GN   Name=ADH5; Synonyms=ADHX, FDH;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0005504; F:fatty acid binding; IDA:UniProtKB.
DR   GO; GO:0018467; F:formaldehyde dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0051903; F:S-(hydroxymethyl)glutathione dehydrogenase activity; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006068; P:ethanol catabolic process; IEA:Ensembl.
DR   GO; GO:0006069; P:ethanol oxidation; IEA:InterPro.
DR   GO; GO:0046294; P:formaldehyde catabolic process; IEA:Ensembl.
DR   GO; GO:0018119; P:peptidyl-cysteine S-nitrosylation; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:Ensembl.
DR   GO; GO:0051775; P:response to redox state; IDA:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; IEA:Ensembl.
//
ID   ADIG_HUMAN              Reviewed;          80 AA.
AC   Q0VDE8;
DE   RecName: Full=Adipogenin;
GN   Name=ADIG;
DR   GO; GO:0050873; P:brown fat cell differentiation; ISS:HGNC.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:HGNC.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0050872; P:white fat cell differentiation; ISS:HGNC.
//
ID   ADIPO_HUMAN             Reviewed;         244 AA.
AC   Q15848; Q58EX9;
DE   RecName: Full=Adiponectin;
DE   AltName: Full=30 kDa adipocyte complement-related protein;
DE   AltName: Full=Adipocyte complement-related 30 kDa protein;
DE            Short=ACRP30;
DE   AltName: Full=Adipocyte, C1q and collagen domain-containing protein;
DE   AltName: Full=Adipose most abundant gene transcript 1 protein;
DE            Short=apM-1;
DE   AltName: Full=Gelatin-binding protein;
DE   Flags: Precursor;
GN   Name=ADIPOQ; Synonyms=ACDC, ACRP30, APM1, GBP28;
DR   GO; GO:0005125; F:cytokine activity; NAS:BHF-UCL.
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; ISS:UniProtKB.
DR   GO; GO:0033691; F:sialic acid binding; IDA:UniProtKB.
DR   GO; GO:0033211; P:adiponectin-activated signaling pathway; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; ISS:UniProtKB.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0070994; P:detection of oxidative stress; ISS:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; ISS:UniProtKB.
DR   GO; GO:0019395; P:fatty acid oxidation; ISS:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0051899; P:membrane depolarization; IEA:Ensembl.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; ISS:BHF-UCL.
DR   GO; GO:0030853; P:negative regulation of granulocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0090317; P:negative regulation of intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0045715; P:negative regulation of low-density lipoprotein particle receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; IDA:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:2000590; P:negative regulation of metanephric mesenchymal cell migration; ISS:UniProtKB.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IDA:BHF-UCL.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000584; P:negative regulation of platelet-derived growth factor receptor-alpha signaling pathway; ISS:UniProtKB.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:1900121; P:negative regulation of receptor binding; IDA:UniProtKB.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IDA:UniProtKB.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050805; P:negative regulation of synaptic transmission; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:2000481; P:positive regulation of cAMP-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0045923; P:positive regulation of fatty acid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.
DR   GO; GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:UniProtKB.
DR   GO; GO:2000478; P:positive regulation of metanephric glomerular visceral epithelial cell development; ISS:UniProtKB.
DR   GO; GO:0071639; P:positive regulation of monocyte chemotactic protein-1 production; IDA:UniProtKB.
DR   GO; GO:0033034; P:positive regulation of myeloid cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000534; P:positive regulation of renal albumin absorption; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; ISS:BHF-UCL.
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IDA:UniProtKB.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; ISS:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0070543; P:response to linoleic acid; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0009744; P:response to sucrose; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.
//
ID   ADIP_HUMAN              Reviewed;         614 AA.
AC   Q9Y2D8; A8K8W0; B4DFE3; D3DT13; J3KR02; Q6P2P8; Q6ULS1; Q7L168;
AC   Q9UIX0;
DE   RecName: Full=Afadin- and alpha-actinin-binding protein;
DE            Short=ADIP;
DE   AltName: Full=Afadin DIL domain-interacting protein;
DE   AltName: Full=SSX2-interacting protein;
GN   Name=SSX2IP; Synonyms=KIAA0923;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; IEA:Ensembl.
DR   GO; GO:0035020; P:regulation of Rac protein signal transduction; IEA:Ensembl.
//
ID   ADIRF_HUMAN             Reviewed;          76 AA.
AC   Q15847;
DE   RecName: Full=Adipogenesis regulatory factor;
DE   AltName: Full=Adipogenesis factor rich in obesity;
DE   AltName: Full=Adipose most abundant gene transcript 2 protein;
DE   AltName: Full=Adipose-specific protein 2;
DE            Short=apM-2;
GN   Name=ADIRF; Synonyms=AFRO, APM2, C10orf116;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0072719; P:cellular response to cisplatin; IDA:UniProtKB.
DR   GO; GO:0071478; P:cellular response to radiation; IDA:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2001023; P:regulation of response to drug; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ADK_HUMAN               Reviewed;         362 AA.
AC   P55263; B7Z783; B7Z800; O00741; O00742; Q16710; Q5JQ10; Q5JQ11;
AC   Q9BTN2;
DE   RecName: Full=Adenosine kinase;
DE            Short=AK;
DE            EC=2.7.1.20;
DE   AltName: Full=Adenosine 5'-phosphotransferase;
GN   Name=ADK;
DR   GuidetoPHARMACOLOGY; 1231; -.
DR   GO; GO:0004001; F:adenosine kinase activity; EXP:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0046085; P:adenosine metabolic process; IEA:Ensembl.
DR   GO; GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006175; P:dATP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0009156; P:ribonucleoside monophosphate biosynthetic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044342; P:type B pancreatic cell proliferation; IEA:Ensembl.
//
ID   ADM2_HUMAN              Reviewed;         148 AA.
AC   Q7Z4H4; Q3LFQ0;
DE   RecName: Full=ADM2;
DE   AltName: Full=Intermedin;
DE   Contains:
DE     RecName: Full=Adrenomedullin-2;
DE              Short=AM2;
DE     AltName: Full=Intermedin-long;
DE              Short=IMDL;
DE   Contains:
DE     RecName: Full=Intermedin-short;
DE              Short=IMDS;
DE   Flags: Precursor;
GN   Name=ADM2; Synonyms=AM2;
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007586; P:digestion; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:MGI.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   ADM5_HUMAN              Reviewed;         153 AA.
AC   C9JUS6;
DE   RecName: Full=Putative adrenomedullin-5-like protein;
DE   Flags: Precursor;
GN   Name=ADM5; Synonyms=C19orf76;
//
ID   ADML_HUMAN              Reviewed;         185 AA.
AC   P35318; B2R793; D3DQV3; Q6FGW2;
DE   RecName: Full=ADM;
DE   Contains:
DE     RecName: Full=Adrenomedullin;
DE              Short=AM;
DE   Contains:
DE     RecName: Full=Proadrenomedullin N-20 terminal peptide;
DE     AltName: Full=ProAM N-terminal 20 peptide;
DE              Short=PAMP;
DE              Short=ProAM-N20;
DE   Flags: Precursor;
GN   Name=ADM; Synonyms=AM;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IDA:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0046879; P:hormone secretion; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0045906; P:negative regulation of vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0031102; P:neuron projection regeneration; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0006701; P:progesterone biosynthetic process; TAS:ProtInc.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEA:Ensembl.
DR   GO; GO:0097084; P:vascular smooth muscle cell development; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IDA:UniProtKB.
//
ID   ADNP2_HUMAN             Reviewed;        1131 AA.
AC   Q6IQ32; A8K951; O94943; Q9H9P3;
DE   RecName: Full=ADNP homeobox protein 2;
DE   AltName: Full=Zinc finger protein 508;
GN   Name=ADNP2; Synonyms=KIAA0863, ZNF508;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ADNP_HUMAN              Reviewed;        1102 AA.
AC   Q9H2P0; E1P5Y2; O94881; Q5BKU2; Q9UG34;
DE   RecName: Full=Activity-dependent neuroprotector homeobox protein;
DE   AltName: Full=Activity-dependent neuroprotective protein;
GN   Name=ADNP; Synonyms=ADNP1, KIAA0784;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ADPGK_HUMAN             Reviewed;         497 AA.
AC   Q9BRR6; Q49AU7; Q8NBI1; Q8WZ90; Q96NF8; Q9H0A7;
DE   RecName: Full=ADP-dependent glucokinase;
DE            Short=ADP-GK;
DE            Short=ADPGK;
DE            EC=2.7.1.147;
DE   AltName: Full=RbBP-35;
DE   Flags: Precursor;
GN   Name=ADPGK; ORFNames=PSEC0260;
DR   GO; GO:0043843; F:ADP-specific glucokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
//
ID   ADPPT_HUMAN             Reviewed;         309 AA.
AC   Q9NRN7; B2R6D1; Q9C068; Q9P0Q3; Q9UG80; Q9Y389;
DE   RecName: Full=L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase;
DE            EC=2.7.8.-;
DE   AltName: Full=4'-phosphopantetheinyl transferase;
DE   AltName: Full=Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase;
DE            Short=AASD-PPT;
DE   AltName: Full=LYS5 ortholog;
GN   Name=AASDHPPT; ORFNames=CGI-80, HAH-P, HSPC223, x0005;
DR   GO; GO:0008897; F:holo-[acyl-carrier-protein] synthase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   ADPRH_HUMAN             Reviewed;         357 AA.
AC   P54922; B2R8H1; D3DN83;
DE   RecName: Full=[Protein ADP-ribosylarginine] hydrolase;
DE            Short=ADP-ribosylarginine hydrolase;
DE            EC=3.2.2.19;
DE   AltName: Full=ADP-ribose-L-arginine cleaving enzyme;
GN   Name=ADPRH; Synonyms=ARH1;
DR   GO; GO:0003875; F:ADP-ribosylarginine hydrolase activity; IMP:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; IMP:UniProtKB.
DR   GO; GO:0051725; P:protein de-ADP-ribosylation; IEA:InterPro.
//
ID   ADPRM_HUMAN             Reviewed;         342 AA.
AC   Q3LIE5; A8K9B4; D3DTS4; Q9BVD4; Q9NRU8;
DE   RecName: Full=Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase;
DE            EC=3.6.1.13;
DE            EC=3.6.1.16;
DE            EC=3.6.1.53;
DE   AltName: Full=ADPRibase-Mn;
DE   AltName: Full=CDP-choline phosphohydrolase;
GN   Name=ADPRM; Synonyms=C17orf48; ORFNames=MDS006, Nbla03831;
DR   GO; GO:0047631; F:ADP-ribose diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047734; F:CDP-glycerol diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ADR1_HUMAN              Reviewed;         375 AA.
AC   Q96A54; B3KMB0; Q53HS7; Q53YY6; Q9Y360;
DE   RecName: Full=Adiponectin receptor protein 1;
DE   AltName: Full=Progestin and adipoQ receptor family member I;
GN   Name=ADIPOR1; Synonyms=PAQR1, TESBP1A; ORFNames=CGI-45;
DR   GuidetoPHARMACOLOGY; 649; -.
DR   GO; GO:0042562; F:hormone binding; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0033211; P:adiponectin-activated signaling pathway; IBA:RefGenome.
DR   GO; GO:0019395; P:fatty acid oxidation; IDA:UniProtKB.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0033210; P:leptin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IEA:Ensembl.
//
ID   ADR2_HUMAN              Reviewed;         386 AA.
AC   Q86V24; Q53YY5; Q9H737;
DE   RecName: Full=Adiponectin receptor protein 2;
DE   AltName: Full=Progestin and adipoQ receptor family member II;
GN   Name=ADIPOR2; Synonyms=PAQR2;
DR   GuidetoPHARMACOLOGY; 650; -.
DR   GO; GO:0042562; F:hormone binding; ISS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0033211; P:adiponectin-activated signaling pathway; IBA:RefGenome.
DR   GO; GO:0019395; P:fatty acid oxidation; ISS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   ADRB1_HUMAN             Reviewed;         477 AA.
AC   P08588; B0LPE2; Q5T5Y4; Q9UKG7; Q9UKG8;
DE   RecName: Full=Beta-1 adrenergic receptor;
DE   AltName: Full=Beta-1 adrenoreceptor;
DE            Short=Beta-1 adrenoceptor;
GN   Name=ADRB1; Synonyms=ADRB1R, B1AR;
DR   GuidetoPHARMACOLOGY; 28; -.
DR   GO; GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004939; F:beta-adrenergic receptor activity; TAS:ProtInc.
DR   GO; GO:0004940; F:beta1-adrenergic receptor activity; TAS:ProtInc.
DR   GO; GO:0035240; F:dopamine binding; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0051379; F:epinephrine binding; IEA:Ensembl.
DR   GO; GO:0051380; F:norepinephrine binding; IEA:Ensembl.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; IDA:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0071880; P:adenylate cyclase-activating adrenergic receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0002024; P:diet induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0042596; P:fear response; IEA:Ensembl.
DR   GO; GO:0005980; P:glycogen catabolic process; IEA:Ensembl.
DR   GO; GO:0031649; P:heat generation; IEA:Ensembl.
DR   GO; GO:0055088; P:lipid homeostasis; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045986; P:negative regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0035811; P:negative regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:2001259; P:positive regulation of cation channel activity; IEA:Ensembl.
DR   GO; GO:0061051; P:positive regulation of cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0001996; P:positive regulation of heart rate by epinephrine-norepinephrine; IEA:Ensembl.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:1900135; P:positive regulation of renin secretion into blood stream; IEA:Ensembl.
DR   GO; GO:0046878; P:positive regulation of saliva secretion; IEA:Ensembl.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0003061; P:positive regulation of the force of heart contraction by norepinephrine; IEA:Ensembl.
DR   GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IEA:Ensembl.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0002025; P:vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   ADRB2_HUMAN             Reviewed;         413 AA.
AC   P07550; B0LPE4; B2R7X2; O14823; O14824; O14825; O14826; Q4JG18;
AC   Q53GA6; Q6GMT4; Q6P4D8; Q8NEQ9; Q96EC3; Q9UCZ0; Q9UCZ1; Q9UCZ2;
AC   Q9UCZ3; Q9UH95; Q9UHA1; Q9UMZ5;
DE   RecName: Full=Beta-2 adrenergic receptor;
DE   AltName: Full=Beta-2 adrenoreceptor;
DE            Short=Beta-2 adrenoceptor;
GN   Name=ADRB2; Synonyms=ADRB2R, B2AR;
DR   GuidetoPHARMACOLOGY; 29; -.
DR   GO; GO:0004941; F:beta2-adrenergic receptor activity; IDA:HGNC.
DR   GO; GO:0051380; F:norepinephrine binding; IDA:HGNC.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IDA:HGNC.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071875; P:adrenergic receptor signaling pathway; IDA:GOC.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0002032; P:desensitization of G-protein coupled receptor protein signaling pathway by arrestin; IDA:HGNC.
DR   GO; GO:0002024; P:diet induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0008333; P:endosome to lysosome transport; TAS:ProtInc.
DR   GO; GO:0031649; P:heat generation; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045986; P:negative regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:HGNC.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:HGNC.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0042312; P:regulation of vasodilation; IEA:InterPro.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0002025; P:vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
//
ID   ADRB3_HUMAN             Reviewed;         408 AA.
AC   P13945; Q4JFT4;
DE   RecName: Full=Beta-3 adrenergic receptor;
DE   AltName: Full=Beta-3 adrenoreceptor;
DE            Short=Beta-3 adrenoceptor;
GN   Name=ADRB3; Synonyms=ADRB3R, B3AR;
DR   GuidetoPHARMACOLOGY; 30; -.
DR   GO; GO:0004939; F:beta-adrenergic receptor activity; IDA:HGNC.
DR   GO; GO:0004940; F:beta1-adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0015052; F:beta3-adrenergic receptor activity; IMP:HGNC.
DR   GO; GO:0051379; F:epinephrine binding; IEA:Ensembl.
DR   GO; GO:0051380; F:norepinephrine binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IDA:HGNC.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071875; P:adrenergic receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0002024; P:diet induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0031649; P:heat generation; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045823; P:positive regulation of heart contraction; IEA:InterPro.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:HGNC.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0002025; P:vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
//
ID   ADRM1_HUMAN             Reviewed;         407 AA.
AC   Q16186; A0PKB1; Q96FJ7; Q9H1P2;
DE   RecName: Full=Proteasomal ubiquitin receptor ADRM1;
DE   AltName: Full=110 kDa cell membrane glycoprotein;
DE            Short=Gp110;
DE   AltName: Full=Adhesion-regulating molecule 1;
DE            Short=ARM-1;
DE   AltName: Full=Proteasome regulatory particle non-ATPase 13;
DE            Short=hRpn13;
DE   AltName: Full=Rpn13 homolog;
GN   Name=ADRM1; Synonyms=GP110;
DR   GO; GO:0061133; F:endopeptidase activator activity; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0070628; F:proteasome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010950; P:positive regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0043248; P:proteasome assembly; IDA:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:UniProtKB.
//
ID   ADRO_HUMAN              Reviewed;         491 AA.
AC   P22570; B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; Q13716;
AC   Q4PJI0; Q9BU12;
DE   RecName: Full=NADPH:adrenodoxin oxidoreductase, mitochondrial;
DE            Short=AR;
DE            Short=Adrenodoxin reductase;
DE            EC=1.18.1.6;
DE   AltName: Full=Ferredoxin--NADP(+) reductase;
DE            Short=Ferredoxin reductase;
DE   Flags: Precursor;
GN   Name=FDXR; Synonyms=ADXR;
DR   GO; GO:0004324; F:ferredoxin-NADP+ reductase activity; TAS:ProtInc.
DR   GO; GO:0070402; F:NADPH binding; IEA:Ensembl.
DR   GO; GO:0015039; F:NADPH-adrenodoxin reductase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0070995; P:NADPH oxidation; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
//
ID   ADSV_HUMAN              Reviewed;         715 AA.
AC   Q9Y6U3; A8K2U8; Q8NBZ6; Q8WU97; Q96JC7; Q96PY2;
DE   RecName: Full=Adseverin;
DE   AltName: Full=Scinderin;
GN   Name=SCIN; Synonyms=KIAA1905;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; TAS:UniProtKB.
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0051014; P:actin filament severing; IMP:UniProtKB.
DR   GO; GO:0045010; P:actin nucleation; ISS:UniProtKB.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0051047; P:positive regulation of secretion; ISS:UniProtKB.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; ISS:UniProtKB.
//
ID   ADT1_HUMAN              Reviewed;         298 AA.
AC   P12235; D3DP59;
DE   RecName: Full=ADP/ATP translocase 1;
DE   AltName: Full=ADP,ATP carrier protein 1;
DE   AltName: Full=ADP,ATP carrier protein, heart/skeletal muscle isoform T1;
DE   AltName: Full=Adenine nucleotide translocator 1;
DE            Short=ANT 1;
DE   AltName: Full=Solute carrier family 25 member 4;
GN   Name=SLC25A4; Synonyms=ANT1;
DR   GuidetoPHARMACOLOGY; 1062; -.
DR   GO; GO:0015207; F:adenine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0015853; P:adenine transport; TAS:GOC.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; TAS:ProtInc.
DR   GO; GO:0060546; P:negative regulation of necroptotic process; IMP:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ADT2_HUMAN              Reviewed;         298 AA.
AC   P05141; B2RCV1; O43350;
DE   RecName: Full=ADP/ATP translocase 2;
DE   AltName: Full=ADP,ATP carrier protein 2;
DE   AltName: Full=ADP,ATP carrier protein, fibroblast isoform;
DE   AltName: Full=Adenine nucleotide translocator 2;
DE            Short=ANT 2;
DE   AltName: Full=Solute carrier family 25 member 5;
DE   Contains:
DE     RecName: Full=ADP/ATP translocase 2, N-terminally processed;
GN   Name=SLC25A5; Synonyms=ANT2;
DR   GO; GO:0015207; F:adenine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015853; P:adenine transport; TAS:GOC.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ADT3_HUMAN              Reviewed;         298 AA.
AC   P12236; Q96C49;
DE   RecName: Full=ADP/ATP translocase 3;
DE   AltName: Full=ADP,ATP carrier protein 3;
DE   AltName: Full=ADP,ATP carrier protein, isoform T2;
DE            Short=ANT 2;
DE   AltName: Full=Adenine nucleotide translocator 3;
DE            Short=ANT 3;
DE   AltName: Full=Solute carrier family 25 member 6;
DE   Contains:
DE     RecName: Full=ADP/ATP translocase 3, N-terminally processed;
GN   Name=SLC25A6; Synonyms=ANT3; ORFNames=CDABP0051;
DR   GO; GO:0005471; F:ATP:ADP antiporter activity; NAS:UniProtKB.
DR   GO; GO:0046732; P:active induction of host immune response by virus; TAS:Reactome.
DR   GO; GO:0015866; P:ADP transport; NAS:GOC.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0015867; P:ATP transport; NAS:GOC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ADT4_HUMAN              Reviewed;         315 AA.
AC   Q9H0C2;
DE   RecName: Full=ADP/ATP translocase 4;
DE   AltName: Full=ADP,ATP carrier protein 4;
DE   AltName: Full=Adenine nucleotide translocator 4;
DE            Short=ANT 4;
DE   AltName: Full=Solute carrier family 25 member 31;
DE   AltName: Full=Sperm flagellar energy carrier protein;
GN   Name=SLC25A31; Synonyms=AAC4, ANT4, SFEC;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   ADTRP_HUMAN             Reviewed;         230 AA.
AC   Q96IZ2; B2R7T9; B4DV39; Q5THW1;
DE   RecName: Full=Androgen-dependent TFPI-regulating protein;
GN   Name=ADTRP; Synonyms=C6orf105;
//
ID   ADXL_HUMAN              Reviewed;         183 AA.
AC   Q6P4F2;
DE   RecName: Full=Adrenodoxin-like protein, mitochondrial;
DE   AltName: Full=Ferredoxin-1-like protein;
DE   Flags: Precursor;
GN   Name=FDX1L;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ADX_HUMAN               Reviewed;         184 AA.
AC   P10109; B0YJ14; Q53YD6;
DE   RecName: Full=Adrenodoxin, mitochondrial;
DE   AltName: Full=Adrenal ferredoxin;
DE   AltName: Full=Ferredoxin-1;
DE   AltName: Full=Hepatoredoxin;
DE   Flags: Precursor;
GN   Name=FDX1; Synonyms=ADX;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; TAS:ProtInc.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:UniProtKB.
DR   GO; GO:0042446; P:hormone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
//
ID   AEBP1_HUMAN             Reviewed;        1158 AA.
AC   Q8IUX7; Q14113; Q59ER7; Q6ZSC7; Q7KZ79;
DE   RecName: Full=Adipocyte enhancer-binding protein 1;
DE            Short=AE-binding protein 1;
DE   AltName: Full=Aortic carboxypeptidase-like protein;
DE   Flags: Precursor;
GN   Name=AEBP1; Synonyms=ACLP;
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AEBP2_HUMAN             Reviewed;         517 AA.
AC   Q6ZN18; Q59FS5; Q6ZN62; Q96BG3;
DE   RecName: Full=Zinc finger protein AEBP2;
DE   AltName: Full=Adipocyte enhancer-binding protein 2;
DE            Short=AE-binding protein 2;
GN   Name=AEBP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AEDO_HUMAN              Reviewed;         270 AA.
AC   Q96SZ5; B1AL29;
DE   RecName: Full=2-aminoethanethiol dioxygenase;
DE            EC=1.13.11.19;
DE   AltName: Full=Cysteamine dioxygenase;
GN   Name=ADO; Synonyms=C10orf22;
DR   GO; GO:0047800; F:cysteamine dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   AEGP_HUMAN              Reviewed;        1216 AA.
AC   Q6UXC1; A2A3D4; B0QZ81; Q5T5S2; Q8NCX7;
DE   RecName: Full=Apical endosomal glycoprotein;
DE   AltName: Full=MAM domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=MAMDC4; Synonyms=AEGP; ORFNames=UNQ3001/PRO9742;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AEN_HUMAN               Reviewed;         325 AA.
AC   Q8WTP8; C9J571; Q9BSA5; Q9H9X7;
DE   RecName: Full=Apoptosis-enhancing nuclease;
DE            EC=3.1.-.-;
DE   AltName: Full=Interferon-stimulated 20 kDa exonuclease-like 1;
GN   Name=AEN; Synonyms=ISG20L1; ORFNames=SBBI58;
DR   GO; GO:0004527; F:exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
//
ID   AES_HUMAN               Reviewed;         197 AA.
AC   Q08117; B2RBL0; Q12808; Q14CJ1; Q96TG9; Q9UDY9;
DE   RecName: Full=Amino-terminal enhancer of split;
DE            Short=Amino enhancer of split;
DE   AltName: Full=Gp130-associated protein GAM;
DE   AltName: Full=Protein ESP1;
DE   AltName: Full=Protein GRG;
GN   Name=AES; Synonyms=GRG;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0060761; P:negative regulation of response to cytokine stimulus; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:2000210; P:positive regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IDA:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AF10_HUMAN              Reviewed;        1068 AA.
AC   P55197; B1ANA8; Q5JT37; Q5VX90; Q66K63;
DE   RecName: Full=Protein AF-10;
DE   AltName: Full=ALL1-fused gene from chromosome 10 protein;
GN   Name=MLLT10; Synonyms=AF10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AF17_HUMAN              Reviewed;        1093 AA.
AC   P55198; Q59F28; Q96IU3; Q9H5F6; Q9UF49;
DE   RecName: Full=Protein AF-17;
DE   AltName: Full=ALL1-fused gene from chromosome 17 protein;
GN   Name=MLLT6; Synonyms=AF17;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
//
ID   AF1L1_HUMAN             Reviewed;         768 AA.
AC   Q8TED9; Q08AN4; Q08AN5; Q8IW82; Q8N8Z5; Q8N9Q4;
DE   RecName: Full=Actin filament-associated protein 1-like 1;
DE            Short=AFAP1-like protein 1;
GN   Name=AFAP1L1;
//
ID   AF1L2_HUMAN             Reviewed;         818 AA.
AC   Q8N4X5; A8K6P7; B3KVQ8; Q2UZW3; Q8TB54; Q96PX4; Q96SY5;
DE   RecName: Full=Actin filament-associated protein 1-like 2;
DE            Short=AFAP1-like protein 2;
GN   Name=AFAP1L2; Synonyms=KIAA1914, XB130;
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IDA:HGNC.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:HGNC.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:HGNC.
DR   GO; GO:0006954; P:inflammatory response; IDA:HGNC.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:HGNC.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0032675; P:regulation of interleukin-6 production; IDA:HGNC.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IDA:HGNC.
//
ID   AF1Q_HUMAN              Reviewed;          90 AA.
AC   Q13015;
DE   RecName: Full=Protein AF1q;
GN   Name=MLLT11; Synonyms=AF1Q;
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   AF9_HUMAN               Reviewed;         568 AA.
AC   P42568; B1AMQ2; B2R7B3; B7Z755; D3DRJ8; Q8IVB0;
DE   RecName: Full=Protein AF-9;
DE   AltName: Full=ALL1-fused gene from chromosome 9 protein;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein;
DE   AltName: Full=YEATS domain-containing protein 3;
GN   Name=MLLT3; Synonyms=AF9, YEATS3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:MGI.
DR   GO; GO:2000096; P:positive regulation of Wnt signaling pathway, planar cell polarity pathway; IGI:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007379; P:segment specification; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AFAD_HUMAN              Reviewed;        1824 AA.
AC   P55196; O75087; O75088; O75089; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7;
AC   Q9NU92;
DE   RecName: Full=Afadin;
DE   AltName: Full=ALL1-fused gene from chromosome 6 protein;
DE            Short=Protein AF-6;
GN   Name=MLLT4; Synonyms=AF6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   AFAM_HUMAN              Reviewed;         599 AA.
AC   P43652; A8K3E1; Q32MR3; Q4W5C5;
DE   RecName: Full=Afamin;
DE   AltName: Full=Alpha-albumin;
DE            Short=Alpha-Alb;
DE   Flags: Precursor;
GN   Name=AFM; Synonyms=ALB2, ALBA;
DR   GO; GO:0008431; F:vitamin E binding; IDA:UniProtKB.
DR   GO; GO:0051180; P:vitamin transport; IDA:UniProtKB.
//
ID   AFAP1_HUMAN             Reviewed;         730 AA.
AC   Q8N556; A8K442; B4DMU2; E9PDT7; Q59EY5; Q9HBY1;
DE   RecName: Full=Actin filament-associated protein 1;
DE   AltName: Full=110 kDa actin filament-associated protein;
DE            Short=AFAP-110;
GN   Name=AFAP1; Synonyms=AFAP;
//
ID   AFF1_HUMAN              Reviewed;        1210 AA.
AC   P51825; B4DTU1; E9PBM3;
DE   RecName: Full=AF4/FMR2 family member 1;
DE   AltName: Full=ALL1-fused gene from chromosome 4 protein;
DE            Short=Protein AF-4;
DE   AltName: Full=Protein FEL;
DE   AltName: Full=Proto-oncogene AF4;
GN   Name=AFF1; Synonyms=AF4, FEL, MLLT2, PBM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   AFF2_HUMAN              Reviewed;        1311 AA.
AC   P51816; A2RTY4; B4DXD5; B7WNQ1; B7ZLD6; B7ZLD9; O43786; O60215;
AC   P78407; Q13521; Q14323; Q7Z2F7; Q7Z400; Q9UNA5;
DE   RecName: Full=AF4/FMR2 family member 2;
DE   AltName: Full=Fragile X E mental retardation syndrome protein;
DE   AltName: Full=Fragile X mental retardation 2 protein;
DE            Short=FMR2P;
DE            Short=Protein FMR-2;
DE   AltName: Full=Protein Ox19;
GN   Name=AFF2; Synonyms=FMR2, OX19;
DR   GO; GO:0002151; F:G-quadruplex RNA binding; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   AFF3_HUMAN              Reviewed;        1226 AA.
AC   P51826; B7ZM46; B9EGL9; D3DVI6; Q53RD6; Q53S47; Q53SI6; Q53TB9;
AC   Q59F27; Q8IWJ5;
DE   RecName: Full=AF4/FMR2 family member 3;
DE   AltName: Full=Lymphoid nuclear protein related to AF4;
DE            Short=Protein LAF-4;
GN   Name=AFF3; Synonyms=LAF4;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AFF4_HUMAN              Reviewed;        1163 AA.
AC   Q9UHB7; B2RP19; B7WPD2; Q498B2; Q59FB3; Q6P592; Q8TDR1; Q9P0E4;
DE   RecName: Full=AF4/FMR2 family member 4;
DE   AltName: Full=ALL1-fused gene from chromosome 5q31 protein;
DE            Short=Protein AF-5q31;
DE   AltName: Full=Major CDK9 elongation factor-associated protein;
GN   Name=AFF4; Synonyms=AF5Q31, MCEF; ORFNames=HSPC092;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   AFG32_HUMAN             Reviewed;         797 AA.
AC   Q9Y4W6; Q6P1L0;
DE   RecName: Full=AFG3-like protein 2;
DE            EC=3.4.24.-;
DE   AltName: Full=Paraplegin-like protein;
GN   Name=AFG3L2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0042407; P:cristae formation; IEA:Ensembl.
DR   GO; GO:0008053; P:mitochondrial fusion; IEA:Ensembl.
DR   GO; GO:0034982; P:mitochondrial protein processing; IEA:Ensembl.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0060013; P:righting reflex; IEA:Ensembl.
//
ID   AFTIN_HUMAN             Reviewed;         937 AA.
AC   Q6ULP2; D6W5E9; Q6ZM66; Q86VW3; Q8TCF3; Q9H7E3; Q9HAB9; Q9NXS4;
DE   RecName: Full=Aftiphilin;
GN   Name=AFTPH; Synonyms=AFTH;
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AG10A_HUMAN             Reviewed;         473 AA.
AC   Q5BKT4; Q6NS98; Q96DU0; Q96SM6;
DE   RecName: Full=Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase;
DE            EC=2.4.1.256;
DE   AltName: Full=Alpha-1,2-glucosyltransferase ALG10-A;
DE   AltName: Full=Alpha-2-glucosyltransferase ALG10-A;
DE   AltName: Full=Asparagine-linked glycosylation protein 10 homolog A;
GN   Name=ALG10; Synonyms=ALG10A;
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   AG10B_HUMAN             Reviewed;         473 AA.
AC   Q5I7T1; B2RPF4;
DE   RecName: Full=Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase;
DE            EC=2.4.1.256;
DE   AltName: Full=Alpha-1,2-glucosyltransferase ALG10-A;
DE   AltName: Full=Alpha-2-glucosyltransferase ALG10-B;
DE   AltName: Full=Asparagine-linked glycosylation protein 10 homolog B;
DE   AltName: Full=Potassium channel regulator 1;
GN   Name=ALG10B; Synonyms=KCR1;
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   AGA10_HUMAN             Reviewed;         658 AA.
AC   Q5T2P9;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 10;
DE            Short=AGAP-10;
DE   AltName: Full=Centaurin-gamma-like family member 7;
GN   Name=AGAP10; Synonyms=CTGLF7;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AG1L2_HUMAN             Reviewed;         215 AA.
AC   C9J202;
DE   RecName: Full=Putative glycosyltransferase ALG1L2;
DE            EC=2.4.1.-;
GN   Name=ALG1L2;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   AGA11_HUMAN             Reviewed;         550 AA.
AC   Q8TF27; B9EIP7; D3DWE4;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11;
DE            Short=AGAP-11;
DE   AltName: Full=Centaurin-gamma-like protein KIAA1975;
GN   Name=AGAP11; Synonyms=KIAA1975;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGAL_HUMAN              Reviewed;         429 AA.
AC   P06280; Q6LER7;
DE   RecName: Full=Alpha-galactosidase A;
DE            EC=3.2.1.22;
DE   AltName: Full=Alpha-D-galactosidase A;
DE   AltName: Full=Alpha-D-galactoside galactohydrolase;
DE   AltName: Full=Melibiase;
DE   AltName: INN=Agalsidase;
DE   Flags: Precursor;
GN   Name=GLA;
DR   GO; GO:0004557; F:alpha-galactosidase activity; IDA:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IDA:UniProtKB.
DR   GO; GO:0016936; F:galactoside binding; IEA:Ensembl.
DR   GO; GO:0016787; F:hydrolase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0052692; F:raffinose alpha-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0016139; P:glycoside catabolic process; IBA:RefGenome.
DR   GO; GO:0046479; P:glycosphingolipid catabolic process; TAS:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0046477; P:glycosylceramide catabolic process; ISS:UniProtKB.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; ISS:UniProtKB.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   AGAP1_HUMAN             Reviewed;         857 AA.
AC   Q9UPQ3; B2RTX7; Q541S5; Q6P9D7; Q9NV93;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1;
DE            Short=AGAP-1;
DE   AltName: Full=Centaurin-gamma-2;
DE            Short=Cnt-g2;
DE   AltName: Full=GTP-binding and GTPase-activating protein 1;
DE            Short=GGAP1;
GN   Name=AGAP1; Synonyms=CENTG2, KIAA1099;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005543; F:phospholipid binding; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   AGAP2_HUMAN             Reviewed;        1192 AA.
AC   Q99490; A8K9F7; O00578; Q548E0; Q8IWU3;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2;
DE            Short=AGAP-2;
DE   AltName: Full=Centaurin-gamma-1;
DE            Short=Cnt-g1;
DE   AltName: Full=GTP-binding and GTPase-activating protein 2;
DE            Short=GGAP2;
DE   AltName: Full=Phosphatidylinositol 3-kinase enhancer;
DE            Short=PIKE;
GN   Name=AGAP2; Synonyms=CENTG1, KIAA0167;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:MGI.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   AGAP3_HUMAN             Reviewed;         875 AA.
AC   Q96P47; B3KNZ8; Q59EN0; Q96RK3;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3;
DE            Short=AGAP-3;
DE   AltName: Full=CRAM-associated GTPase;
DE            Short=CRAG;
DE   AltName: Full=Centaurin-gamma-3;
DE            Short=Cnt-g3;
DE   AltName: Full=MR1-interacting protein;
DE            Short=MRIP-1;
GN   Name=AGAP3; Synonyms=CENTG3;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   AGAP4_HUMAN             Reviewed;         663 AA.
AC   Q96P64;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4;
DE            Short=AGAP-4;
DE   AltName: Full=Centaurin-gamma-like family member 1;
GN   Name=AGAP4; Synonyms=CTGLF1, MRIP2;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGAP5_HUMAN             Reviewed;         686 AA.
AC   A6NIR3; A8MSN5;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5;
DE            Short=AGAP-5;
DE   AltName: Full=Centaurin-gamma-like family member 2;
GN   Name=AGAP5; Synonyms=CTGLF2;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGAP7_HUMAN             Reviewed;         663 AA.
AC   Q5VUJ5; A6NGH4;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 7;
DE            Short=AGAP-7;
DE   AltName: Full=Centaurin-gamma-like family member 4;
GN   Name=AGAP7; Synonyms=CTGLF4;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGAP6_HUMAN             Reviewed;         663 AA.
AC   Q5VW22;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6;
DE            Short=AGAP-6;
DE   AltName: Full=Centaurin-gamma-like family member 3;
GN   Name=AGAP6; Synonyms=CTGLF3;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGAP8_HUMAN             Reviewed;         663 AA.
AC   Q5SRD3;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 8;
DE            Short=AGAP-8;
DE   AltName: Full=Centaurin-gamma-like family member 5;
GN   Name=AGAP8; Synonyms=CTGLF5;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGAP9_HUMAN             Reviewed;         703 AA.
AC   Q5VTM2; D3YTF3;
DE   RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9;
DE            Short=AGAP-9;
DE   AltName: Full=Centaurin-gamma-like family member 6;
GN   Name=AGAP9; Synonyms=CTGLF6;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGFG1_HUMAN             Reviewed;         562 AA.
AC   P52594; B3KUL1; E9PHX7; Q15277; Q4VAS0; Q4VAS1; Q4VAS3; Q53QT8;
AC   Q53R11;
DE   RecName: Full=Arf-GAP domain and FG repeat-containing protein 1;
DE   AltName: Full=HIV-1 Rev-binding protein;
DE   AltName: Full=Nucleoporin-like protein RIP;
DE   AltName: Full=Rev-interacting protein;
DE   AltName: Full=Rev/Rex activation domain-binding protein;
GN   Name=AGFG1; Synonyms=HRB, RAB, RIP;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   AGFG2_HUMAN             Reviewed;         481 AA.
AC   O95081; O75429; Q96AB9; Q96GL4;
DE   RecName: Full=Arf-GAP domain and FG repeat-containing protein 2;
DE   AltName: Full=HIV-1 Rev-binding protein-like protein;
DE   AltName: Full=Rev/Rex activation domain-binding protein related;
DE            Short=RAB-R;
GN   Name=AGFG2; Synonyms=HRBL, RABR;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   AGGF1_HUMAN             Reviewed;         714 AA.
AC   Q8N302; O00581; Q53YS3; Q9BU84; Q9NW66;
DE   RecName: Full=Angiogenic factor with G patch and FHA domains 1;
DE   AltName: Full=Angiogenic factor VG5Q;
DE            Short=hVG5Q;
DE   AltName: Full=G patch domain-containing protein 7;
DE   AltName: Full=Vasculogenesis gene on 5q protein;
GN   Name=AGGF1; Synonyms=GPATC7, GPATCH7, VG5Q;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; TAS:UniProtKB.
//
ID   AGIT1_HUMAN             Reviewed;         198 AA.
AC   Q9H0P7; A7E1X1; Q2M1M7; Q5TEF2; Q9H5S5;
DE   RecName: Full=Putative uncharacterized protein encoded by AGPAT4-IT1;
DE   AltName: Full=AGPAT4 intronic transcript 1;
GN   Name=AGPAT4-IT1; Synonyms=C6orf59, NCRNA00241;
//
ID   AGK_HUMAN               Reviewed;         422 AA.
AC   Q53H12; Q75KN1; Q96GC3; Q9NP48;
DE   RecName: Full=Acylglycerol kinase, mitochondrial;
DE            Short=hAGK;
DE            EC=2.7.1.107;
DE            EC=2.7.1.94;
DE   AltName: Full=Multiple substrate lipid kinase;
DE            Short=HsMuLK;
DE            Short=MuLK;
DE            Short=Multi-substrate lipid kinase;
DE   Flags: Precursor;
GN   Name=AGK; Synonyms=MULK;
DR   GO; GO:0047620; F:acylglycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0001729; F:ceramide kinase activity; IEA:Ensembl.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   AGM1_HUMAN              Reviewed;         542 AA.
AC   O95394; B2RB65; B4DX94; D6RF12; E1P547; E9PF86; Q5JWR4; Q96J46;
AC   Q9H8G5; Q9NS94; Q9NTT6; Q9UFV5; Q9UIY2;
DE   RecName: Full=Phosphoacetylglucosamine mutase;
DE            Short=PAGM;
DE            EC=5.4.2.3;
DE   AltName: Full=Acetylglucosamine phosphomutase;
DE   AltName: Full=N-acetylglucosamine-phosphate mutase;
DE   AltName: Full=Phosphoglucomutase-3;
DE            Short=PGM 3;
GN   Name=PGM3; Synonyms=AGM1;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004610; F:phosphoacetylglucosamine mutase activity; IDA:UniProtKB.
DR   GO; GO:0004614; F:phosphoglucomutase activity; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006041; P:glucosamine metabolic process; NAS:UniProtKB.
DR   GO; GO:0019255; P:glucose 1-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IBA:RefGenome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IBA:RefGenome.
//
ID   AGO1_HUMAN              Reviewed;         857 AA.
AC   Q9UL18; Q5TA57; Q6P4S0;
DE   RecName: Full=Protein argonaute-1;
DE            Short=Argonaute1;
DE            Short=hAgo1;
DE   AltName: Full=Argonaute RISC catalytic component 1;
DE   AltName: Full=Eukaryotic translation initiation factor 2C 1;
DE            Short=eIF-2C 1;
DE            Short=eIF2C 1;
DE   AltName: Full=Putative RNA-binding protein Q99;
GN   Name=AGO1; Synonyms=EIF2C1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AGO2_HUMAN              Reviewed;         859 AA.
AC   Q9UKV8; Q8TCZ5; Q8WV58; Q96ID1;
DE   RecName: Full=Protein argonaute-2;
DE            Short=Argonaute2;
DE            Short=hAgo2;
DE            EC=3.1.26.n2;
DE   AltName: Full=Argonaute RISC catalytic component 2;
DE   AltName: Full=Eukaryotic translation initiation factor 2C 2;
DE            Short=eIF-2C 2;
DE            Short=eIF2C 2;
DE   AltName: Full=PAZ Piwi domain protein;
DE            Short=PPD;
DE   AltName: Full=Protein slicer;
GN   Name=AGO2; Synonyms=EIF2C2;
DR   GO; GO:0004521; F:endoribonuclease activity; EXP:Reactome.
DR   GO; GO:0070551; F:endoribonuclease activity, cleaving siRNA-paired mRNA; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035198; F:miRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000340; F:RNA 7-methylguanosine cap binding; IDA:UniProtKB.
DR   GO; GO:0035197; F:siRNA binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035279; P:mRNA cleavage involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0031054; P:pre-miRNA processing; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006413; P:translational initiation; NAS:GOC.
//
ID   AGO4_HUMAN              Reviewed;         861 AA.
AC   Q9HCK5; A7MD27;
DE   RecName: Full=Protein argonaute-4;
DE            Short=Argonaute4;
DE            Short=hAgo4;
DE   AltName: Full=Argonaute RISC catalytic component 4;
DE   AltName: Full=Eukaryotic translation initiation factor 2C 4;
DE            Short=eIF-2C 4;
DE            Short=eIF2C 4;
GN   Name=AGO4; Synonyms=EIF2C4, KIAA1567;
DR   GO; GO:0035198; F:miRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
//
ID   AGO3_HUMAN              Reviewed;         860 AA.
AC   Q9H9G7; B1ALI0; Q5TA55; Q9H1U6;
DE   RecName: Full=Protein argonaute-3;
DE            Short=Argonaute3;
DE            Short=hAgo3;
DE   AltName: Full=Argonaute RISC catalytic component 3;
DE   AltName: Full=Eukaryotic translation initiation factor 2C 3;
DE            Short=eIF-2C 3;
DE            Short=eIF2C 3;
GN   Name=AGO3; Synonyms=EIF2C3;
DR   GO; GO:0035198; F:miRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0072091; P:regulation of stem cell proliferation; IMP:UniProtKB.
//
ID   AGR2_HUMAN              Reviewed;         175 AA.
AC   O95994;
DE   RecName: Full=Anterior gradient protein 2 homolog;
DE            Short=AG-2;
DE            Short=hAG-2;
DE   AltName: Full=HPC8;
DE   AltName: Full=Secreted cement gland protein XAG-2 homolog;
DE   Flags: Precursor;
GN   Name=AGR2; Synonyms=AG2; ORFNames=UNQ515/PRO1030;
DR   GO; GO:0002162; F:dystroglycan binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060480; P:lung goblet cell differentiation; IEA:Ensembl.
DR   GO; GO:0070254; P:mucus secretion; ISS:UniProtKB.
//
ID   AGR3_HUMAN              Reviewed;         166 AA.
AC   Q8TD06; A4D120;
DE   RecName: Full=Anterior gradient protein 3 homolog;
DE            Short=AG-3;
DE            Short=AG3;
DE            Short=hAG-3;
DE   AltName: Full=Breast cancer membrane protein 11;
DE   Flags: Precursor;
GN   Name=AGR3; Synonyms=BCMP11; ORFNames=UNQ642/PRO1272;
DR   GO; GO:0002162; F:dystroglycan binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   AGRIN_HUMAN             Reviewed;        2067 AA.
AC   O00468; Q5SVA1; Q5SVA2; Q60FE1; Q7KYS8; Q8N4J5; Q96IC1; Q9BTD4;
DE   RecName: Full=Agrin;
DE   Contains:
DE     RecName: Full=Agrin N-terminal 110 kDa subunit;
DE   Contains:
DE     RecName: Full=Agrin C-terminal 110 kDa subunit;
DE   Contains:
DE     RecName: Full=Agrin C-terminal 90 kDa fragment;
DE              Short=C90;
DE   Contains:
DE     RecName: Full=Agrin C-terminal 22 kDa fragment;
DE              Short=C22;
DE   Flags: Precursor;
GN   Name=AGRN; Synonyms=AGRIN;
DR   GO; GO:0030548; F:acetylcholine receptor regulator activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0035374; F:chondroitin sulfate binding; ISS:UniProtKB.
DR   GO; GO:0002162; F:dystroglycan binding; ISS:UniProtKB.
DR   GO; GO:0043395; F:heparan sulfate proteoglycan binding; ISS:UniProtKB.
DR   GO; GO:0043236; F:laminin binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033691; F:sialic acid binding; ISS:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; TAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0045213; P:neurotransmitter receptor metabolic process; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; ISS:UniProtKB.
DR   GO; GO:0045887; P:positive regulation of synaptic growth at neuromuscular junction; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0043113; P:receptor clustering; IDA:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050808; P:synapse organization; TAS:UniProtKB.
//
ID   AGRP_HUMAN              Reviewed;         132 AA.
AC   O00253; O15459; Q2TBD9;
DE   RecName: Full=Agouti-related protein;
DE   Flags: Precursor;
GN   Name=AGRP; Synonyms=AGRT, ART;
DR   GO; GO:0005184; F:neuropeptide hormone activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008343; P:adult feeding behavior; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:InterPro.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:0009648; P:photoperiodism; IEA:Ensembl.
DR   GO; GO:2000253; P:positive regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0060259; P:regulation of feeding behavior; IDA:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   AGSK1_HUMAN             Reviewed;         129 AA.
AC   Q9BXM8;
DE   RecName: Full=Putative colon cancer-associated antigen SK1;
DE            Short=AgSK1;
//
ID   AGT2_HUMAN              Reviewed;         514 AA.
AC   Q9BYV1; Q53FB4; Q53FY7; Q53G03; Q5W7Q1;
DE   RecName: Full=Alanine--glyoxylate aminotransferase 2, mitochondrial;
DE            Short=AGT 2;
DE            EC=2.6.1.44;
DE   AltName: Full=(R)-3-amino-2-methylpropionate--pyruvate transaminase;
DE            EC=2.6.1.40;
DE   AltName: Full=Beta-ALAAT II;
DE   AltName: Full=Beta-alanine-pyruvate aminotransferase;
DE   AltName: Full=D-AIBAT;
DE   Flags: Precursor;
GN   Name=AGXT2; Synonyms=AGT2;
DR   GO; GO:0047305; F:(R)-3-amino-2-methylpropionate-pyruvate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008453; F:alanine-glyoxylate transaminase activity; IDA:BHF-UCL.
DR   GO; GO:0016223; F:beta-alanine-pyruvate transaminase activity; IEA:Ensembl.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019265; P:glycine biosynthetic process, by transamination of glyoxylate; IDA:BHF-UCL.
DR   GO; GO:0009436; P:glyoxylate catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046487; P:glyoxylate metabolic process; TAS:Reactome.
DR   GO; GO:0019481; P:L-alanine catabolic process, by transamination; IDA:BHF-UCL.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AGTR1_HUMAN             Reviewed;         359 AA.
AC   P30556; Q13725; Q8TBK4;
DE   RecName: Full=Type-1 angiotensin II receptor;
DE   AltName: Full=AT1AR;
DE   AltName: Full=AT1BR;
DE   AltName: Full=Angiotensin II type-1 receptor;
DE            Short=AT1;
GN   Name=AGTR1; Synonyms=AGTR1A, AGTR1B, AT2R1, AT2R1B;
DR   GuidetoPHARMACOLOGY; 34; -.
DR   GO; GO:0001596; F:angiotensin type I receptor activity; IDA:BHF-UCL.
DR   GO; GO:0004945; F:angiotensin type II receptor activity; IDA:UniProtKB.
DR   GO; GO:0031711; F:bradykinin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0038166; P:angiotensin-activated signaling pathway; IDA:GOC.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; NAS:BHF-UCL.
DR   GO; GO:0086097; P:phospholipase C-activating angiotensin-activated signaling pathway; IDA:GOC.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; IMP:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:BHF-UCL.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0033864; P:positive regulation of NAD(P)H oxidase activity; TAS:BHF-UCL.
DR   GO; GO:0032430; P:positive regulation of phospholipase A2 activity; IMP:BHF-UCL.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; TAS:BHF-UCL.
DR   GO; GO:0002034; P:regulation of blood vessel size by renin-angiotensin; IC:BHF-UCL.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0035813; P:regulation of renal sodium excretion; NAS:BHF-UCL.
DR   GO; GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IC:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0042312; P:regulation of vasodilation; IC:BHF-UCL.
DR   GO; GO:0002018; P:renin-angiotensin regulation of aldosterone production; NAS:BHF-UCL.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
//
ID   AGTR2_HUMAN             Reviewed;         363 AA.
AC   P50052; B2R9V1; Q13016; Q6FGY7;
DE   RecName: Full=Type-2 angiotensin II receptor;
DE   AltName: Full=Angiotensin II type-2 receptor;
DE            Short=AT2;
GN   Name=AGTR2;
DR   GuidetoPHARMACOLOGY; 35; -.
DR   GO; GO:0004945; F:angiotensin type II receptor activity; IPI:BHF-UCL.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048019; F:receptor antagonist activity; TAS:BHF-UCL.
DR   GO; GO:0035932; P:aldosterone secretion; IEA:Ensembl.
DR   GO; GO:0038166; P:angiotensin-activated signaling pathway; IPI:GOC.
DR   GO; GO:0007610; P:behavior; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; TAS:BHF-UCL.
DR   GO; GO:0007420; P:brain development; NAS:BHF-UCL.
DR   GO; GO:0002035; P:brain renin-angiotensin system; IEA:Ensembl.
DR   GO; GO:0061049; P:cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0006883; P:cellular sodium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0021695; P:cerebellar cortex development; IEA:Ensembl.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IEA:Ensembl.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; ISS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:BHF-UCL.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; NAS:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; TAS:BHF-UCL.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0010459; P:negative regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0032304; P:negative regulation of icosanoid secretion; IEA:Ensembl.
DR   GO; GO:0051387; P:negative regulation of neurotrophin TRK receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:BHF-UCL.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0072300; P:positive regulation of metanephric glomerulus development; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; ISS:BHF-UCL.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IDA:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
DR   GO; GO:0035566; P:regulation of metanephros size; IEA:Ensembl.
DR   GO; GO:0001991; P:regulation of systemic arterial blood pressure by circulatory renin-angiotensin; ISS:BHF-UCL.
DR   GO; GO:0042990; P:regulation of transcription factor import into nucleus; IEA:Ensembl.
DR   GO; GO:0002018; P:renin-angiotensin regulation of aldosterone production; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0002033; P:vasodilation by angiotensin involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
//
ID   AHDC1_HUMAN             Reviewed;        1603 AA.
AC   Q5TGY3; Q5TGY4; Q6PJK1; Q6ZUQ6; Q99769; Q9NUF5;
DE   RecName: Full=AT-hook DNA-binding motif-containing protein 1;
GN   Name=AHDC1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   AHI1_HUMAN              Reviewed;        1196 AA.
AC   Q8N157; E1P584; Q4FD35; Q504T3; Q5TCP9; Q6P098; Q6PIT6; Q8NDX0;
AC   Q9H0H2;
DE   RecName: Full=Jouberin;
DE   AltName: Full=Abelson helper integration site 1 protein homolog;
DE            Short=AHI-1;
GN   Name=AHI1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; ISS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0035844; P:cloaca development; ISS:UniProtKB.
DR   GO; GO:0001947; P:heart looping; ISS:UniProtKB.
DR   GO; GO:0030902; P:hindbrain development; ISS:UniProtKB.
DR   GO; GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.
DR   GO; GO:0070986; P:left/right axis specification; ISS:UniProtKB.
DR   GO; GO:0001738; P:morphogenesis of a polarized epithelium; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0071599; P:otic vesicle development; ISS:UniProtKB.
DR   GO; GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.
DR   GO; GO:0030862; P:positive regulation of polarized epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.
DR   GO; GO:0039008; P:pronephric nephron tubule morphogenesis; ISS:UniProtKB.
DR   GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR   GO; GO:0050795; P:regulation of behavior; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
DR   GO; GO:0065001; P:specification of axis polarity; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006903; P:vesicle targeting; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   AHNK2_HUMAN             Reviewed;        5795 AA.
AC   Q8IVF2; Q5BKX7; Q7Z343; Q7Z358; Q7Z394; Q7Z3G0; Q86WQ6; Q8IYY1;
AC   Q8N3G4; Q96EX9;
DE   RecName: Full=Protein AHNAK2;
GN   Name=AHNAK2; Synonyms=C14orf78, KIAA2019;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
//
ID   AHNK_HUMAN              Reviewed;        5890 AA.
AC   Q09666; A1A586;
DE   RecName: Full=Neuroblast differentiation-associated protein AHNAK;
DE   AltName: Full=Desmoyokin;
GN   Name=AHNAK; Synonyms=PM227;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProt.
DR   GO; GO:0097493; F:structural molecule activity conferring elasticity; ISS:UniProt.
DR   GO; GO:0051259; P:protein oligomerization; ISS:UniProt.
DR   GO; GO:0043484; P:regulation of RNA splicing; ISS:UniProt.
DR   GO; GO:1901385; P:regulation of voltage-gated calcium channel activity; IMP:UniProt.
//
ID   AHRR_HUMAN              Reviewed;         701 AA.
AC   A9YTQ3; A7MBN5; D6RAZ1; Q9HAZ3; Q9ULI6;
DE   RecName: Full=Aryl hydrocarbon receptor repressor;
DE            Short=AhR repressor;
DE            Short=AhRR;
DE   AltName: Full=Class E basic helix-loop-helix protein 77;
DE            Short=bHLHe77;
GN   Name=AHRR; Synonyms=BHLHE77, KIAA1234;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AHR_HUMAN               Reviewed;         848 AA.
AC   P35869; A4D130; Q13728; Q13803; Q13804;
DE   RecName: Full=Aryl hydrocarbon receptor;
DE            Short=Ah receptor;
DE            Short=AhR;
DE   AltName: Full=Class E basic helix-loop-helix protein 76;
DE            Short=bHLHe76;
DE   Flags: Precursor;
GN   Name=AHR; Synonyms=BHLHE76;
DR   GO; GO:0003677; F:DNA binding; IDA:DFLAT.
DR   GO; GO:0035326; F:enhancer binding; IDA:MGI.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; TAS:DFLAT.
DR   GO; GO:0046982; F:protein heterodimerization activity; TAS:DFLAT.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:DFLAT.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; NAS:DFLAT.
DR   GO; GO:0007049; P:cell cycle; TAS:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IEA:Ensembl.
DR   GO; GO:0030850; P:prostate gland development; IEA:Ensembl.
DR   GO; GO:0030888; P:regulation of B cell proliferation; IDA:DFLAT.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:DFLAT.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:DFLAT.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0009410; P:response to xenobiotic stimulus; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:DFLAT.
//
ID   AHSA1_HUMAN             Reviewed;         338 AA.
AC   O95433; B2R9L2; Q96IL6; Q9P060;
DE   RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1;
DE            Short=AHA1;
DE   AltName: Full=p38;
GN   Name=AHSA1; Synonyms=C14orf3; ORFNames=HSPC322;
DR   GO; GO:0001671; F:ATPase activator activity; IDA:MGI.
DR   GO; GO:0051087; F:chaperone binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:GOC.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   AHSA2_HUMAN             Reviewed;         299 AA.
AC   Q719I0; B3KS51; D6W5E0; Q8NDU5;
DE   RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 2;
GN   Name=AHSA2;
DR   GO; GO:0001671; F:ATPase activator activity; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   AHSP_HUMAN              Reviewed;         102 AA.
AC   Q9NZD4; Q8TD01;
DE   RecName: Full=Alpha-hemoglobin-stabilizing protein;
DE   AltName: Full=Erythroid differentiation-related factor;
DE   AltName: Full=Erythroid-associated factor;
GN   Name=AHSP; Synonyms=EDRF, ERAF;
DR   GO; GO:0030492; F:hemoglobin binding; NAS:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0020027; P:hemoglobin metabolic process; NAS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0050821; P:protein stabilization; IEA:InterPro.
//
ID   AICDA_HUMAN             Reviewed;         198 AA.
AC   Q9GZX7; Q6QJ81; Q8NFC1;
DE   RecName: Full=Single-stranded DNA cytosine deaminase;
DE            EC=3.5.4.38;
DE   AltName: Full=Activation-induced cytidine deaminase;
DE   AltName: Full=Cytidine aminohydrolase;
GN   Name=AICDA; Synonyms=AID;
DR   GO; GO:0004126; F:cytidine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030183; P:B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0090310; P:negative regulation of methylation-dependent chromatin silencing; IDA:UniProtKB.
DR   GO; GO:0016445; P:somatic diversification of immunoglobulins; IDA:UniProtKB.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:UniProtKB.
//
ID   AIDA_HUMAN              Reviewed;         306 AA.
AC   Q96BJ3; A8K1F0; Q49A81; Q5JRA4; Q658P1; Q9H9E8;
DE   RecName: Full=Axin interactor, dorsalization-associated protein;
DE   AltName: Full=Axin interaction partner and dorsalization antagonist;
GN   Name=AIDA; Synonyms=C1orf80;
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; ISS:UniProtKB.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IDA:MGI.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; ISS:UniProtKB.
//
ID   AIF1L_HUMAN             Reviewed;         150 AA.
AC   Q9BQI0; B2RBC4; Q6ZR40; Q8NAX7; Q8WU47; Q9H9G0;
DE   RecName: Full=Allograft inflammatory factor 1-like;
DE   AltName: Full=Ionized calcium-binding adapter molecule 2;
GN   Name=AIF1L; Synonyms=C9orf58, IBA2; ORFNames=UNQ672/PRO1306;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   AIF1_HUMAN              Reviewed;         147 AA.
AC   P55008; A8K406; O43904; Q9UIV4; Q9UKS9;
DE   RecName: Full=Allograft inflammatory factor 1;
DE            Short=AIF-1;
DE   AltName: Full=Ionized calcium-binding adapter molecule 1;
DE   AltName: Full=Protein G1;
GN   Name=AIF1; Synonyms=G1, IBA1;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0001774; P:microglial cell activation; NAS:UniProtKB.
DR   GO; GO:0071672; P:negative regulation of smooth muscle cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006911; P:phagocytosis, engulfment; ISS:UniProtKB.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0071673; P:positive regulation of smooth muscle cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000406; P:positive regulation of T cell migration; IDA:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0097178; P:ruffle assembly; ISS:UniProtKB.
//
ID   AIFM1_HUMAN             Reviewed;         613 AA.
AC   O95831; A4QPB4; B1ALN1; B2RB08; D3DTE9; Q1L6K4; Q1L6K6; Q2QKE4;
AC   Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4;
DE   RecName: Full=Apoptosis-inducing factor 1, mitochondrial;
DE            EC=1.1.1.-;
DE   AltName: Full=Programmed cell death protein 8;
DE   Flags: Precursor;
GN   Name=AIFM1; Synonyms=AIF, PDCD8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; TAS:ProtInc.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016174; F:NAD(P)H oxidase activity; TAS:UniProtKB.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; TAS:UniProtKB.
DR   GO; GO:0006308; P:DNA catabolic process; TAS:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:UniProtKB.
//
ID   AIFM2_HUMAN             Reviewed;         373 AA.
AC   Q9BRQ8; B3KXI0; Q63Z39;
DE   RecName: Full=Apoptosis-inducing factor 2;
DE            EC=1.-.-.-;
DE   AltName: Full=Apoptosis-inducing factor homologous mitochondrion-associated inducer of death;
DE   AltName: Full=Apoptosis-inducing factor-like mitochondrion-associated inducer of death;
DE   AltName: Full=p53-responsive gene 3 protein;
GN   Name=AIFM2; Synonyms=AMID, PRG3;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IBA:RefGenome.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
//
ID   AIFM3_HUMAN             Reviewed;         605 AA.
AC   Q96NN9; B7WP37; D3DX37; D3DX38; Q6ZT44; Q8N1V3; Q8N5E0;
DE   RecName: Full=Apoptosis-inducing factor 3;
DE            EC=1.-.-.-;
DE   AltName: Full=Apoptosis-inducing factor-like protein;
GN   Name=AIFM3; Synonyms=AIFL;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:BHF-UCL.
//
ID   AIG1_HUMAN              Reviewed;         245 AA.
AC   Q9NVV5; B4DPX2; C9J569; Q5T2H2; Q6N047; Q7Z378; Q8TB14; Q9Y3A9;
AC   Q9Y5B4;
DE   RecName: Full=Androgen-induced gene 1 protein;
DE            Short=AIG-1;
GN   Name=AIG1; ORFNames=CGI-103;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   AIM1_HUMAN              Reviewed;        1723 AA.
AC   Q9Y4K1; O00296; Q5VWJ2;
DE   RecName: Full=Absent in melanoma 1 protein;
DE   AltName: Full=Beta/gamma crystallin domain-containing protein 1;
GN   Name=AIM1; Synonyms=CRYBG1;
//
ID   AIM1L_HUMAN             Reviewed;         616 AA.
AC   Q8N1P7; B2RNG3; Q5T137; Q5T150;
DE   RecName: Full=Absent in melanoma 1-like protein;
DE   AltName: Full=Beta/gamma crystallin domain-containing protein 2;
GN   Name=AIM1L; Synonyms=CRYBG2;
//
ID   AIM2_HUMAN              Reviewed;         343 AA.
AC   O14862; A8K7M7; Q5T3V9; Q96FG9;
DE   RecName: Full=Interferon-inducible protein AIM2;
DE   AltName: Full=Absent in melanoma 2;
GN   Name=AIM2;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002218; P:activation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035690; P:cellular response to drug; IDA:MGI.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050702; P:interleukin-1 beta secretion; IMP:MGI.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2001056; P:positive regulation of cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; ISS:UniProtKB.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; IDA:UniProtKB.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0070269; P:pyroptosis; IDA:UniProtKB.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
//
ID   AIMP1_HUMAN             Reviewed;         312 AA.
AC   Q12904; B3KTR2; B4E1S7; Q6FG28; Q96CQ9;
DE   RecName: Full=Aminoacyl tRNA synthase complex-interacting multifunctional protein 1;
DE   AltName: Full=Multisynthase complex auxiliary component p43;
DE   Contains:
DE     RecName: Full=Endothelial monocyte-activating polypeptide 2;
DE              Short=EMAP-2;
DE     AltName: Full=Endothelial monocyte-activating polypeptide II;
DE              Short=EMAP-II;
DE     AltName: Full=Small inducible cytokine subfamily E member 1;
GN   Name=AIMP1; Synonyms=EMAP2, SCYE1;
DR   GO; GO:0005125; F:cytokine activity; ISS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0000049; F:tRNA binding; IDA:HGNC.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:HGNC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; IDA:HGNC.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:HGNC.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   AIMP2_HUMAN             Reviewed;         320 AA.
AC   Q13155; Q75MR1; Q96CZ5; Q9P1L2;
DE   RecName: Full=Aminoacyl tRNA synthase complex-interacting multifunctional protein 2;
DE   AltName: Full=Multisynthase complex auxiliary component p38;
DE   AltName: Full=Protein JTV-1;
GN   Name=AIMP2; Synonyms=JTV1; ORFNames=PRO0992;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0060510; P:Type II pneumocyte differentiation; IEA:Ensembl.
//
ID   AINX_HUMAN              Reviewed;         499 AA.
AC   Q16352; B1AQK0; Q9BRC5;
DE   RecName: Full=Alpha-internexin;
DE            Short=Alpha-Inx;
DE   AltName: Full=66 kDa neurofilament protein;
DE            Short=NF-66;
DE            Short=Neurofilament-66;
DE   AltName: Full=Neurofilament 5;
GN   Name=INA; Synonyms=NEF5;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0060052; P:neurofilament cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   AIPL1_HUMAN             Reviewed;         384 AA.
AC   Q9NZN9; D3DTM4; Q659W3; Q659W4; Q6ZZB6; Q8N6A0; Q9H873; Q9NS10;
DE   RecName: Full=Aryl-hydrocarbon-interacting protein-like 1;
GN   Name=AIPL1; Synonyms=AIPL2;
DR   GO; GO:0001918; F:farnesylated protein binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; IEA:Ensembl.
DR   GO; GO:0018343; P:protein farnesylation; IDA:MGI.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0030823; P:regulation of cGMP metabolic process; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   AIP_HUMAN               Reviewed;         330 AA.
AC   O00170; A0SZW3; A0SZW4; A0SZW5; A0SZW6; Q2M3Q2; Q99606;
DE   RecName: Full=AH receptor-interacting protein;
DE            Short=AIP;
DE   AltName: Full=Aryl-hydrocarbon receptor-interacting protein;
DE   AltName: Full=HBV X-associated protein 2;
DE            Short=XAP-2;
DE   AltName: Full=Immunophilin homolog ARA9;
GN   Name=AIP; Synonyms=XAP2;
DR   GO; GO:0036004; F:GAF domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:HGNC.
DR   GO; GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0022417; P:protein maturation by protein folding; IDA:HGNC.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IDA:HGNC.
DR   GO; GO:0010738; P:regulation of protein kinase A signaling; IEA:Ensembl.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IEA:Ensembl.
//
ID   AIRE_HUMAN              Reviewed;         545 AA.
AC   O43918; B2RP50; O43922; O43932; O75745;
DE   RecName: Full=Autoimmune regulator;
DE   AltName: Full=Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;
DE            Short=APECED protein;
GN   Name=AIRE; Synonyms=APECED;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AJAP1_HUMAN             Reviewed;         411 AA.
AC   Q9UKB5; Q9Y229;
DE   RecName: Full=Adherens junction-associated protein 1;
DE   AltName: Full=Membrane protein shrew-1;
GN   Name=AJAP1; Synonyms=MOT8, SHREW1;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   AJUBA_HUMAN             Reviewed;         538 AA.
AC   Q96IF1; A8MX18; D3DS37;
DE   RecName: Full=LIM domain-containing protein ajuba;
GN   Name=AJUBA; Synonyms=JUB;
DR   GO; GO:0045294; F:alpha-catenin binding; IDA:MGI.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035195; P:gene silencing by miRNA; IMP:MGI.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035331; P:negative regulation of hippo signaling; IDA:UniProtKB.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031328; P:positive regulation of cellular biosynthetic process; IEA:Ensembl.
DR   GO; GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:MGI.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:1900037; P:regulation of cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IEA:Ensembl.
//
ID   AK17A_HUMAN             Reviewed;         695 AA.
AC   Q02040; Q02832; Q2TB98; Q5JQ74; Q5JQ76; Q8N6U9;
DE   RecName: Full=A-kinase anchor protein 17A;
DE            Short=AKAP-17A;
DE   AltName: Full=721P;
DE   AltName: Full=B-lymphocyte antigen;
DE   AltName: Full=Protein XE7;
DE   AltName: Full=Protein kinase A-anchoring protein 17A;
DE            Short=PRKA17A;
DE   AltName: Full=Splicing factor, arginine/serine-rich 17A;
GN   Name=AKAP17A; Synonyms=CXYorf3, DXYS155E, SFRS17A, XE7;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051018; F:protein kinase A binding; IDA:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   AK1A1_HUMAN             Reviewed;         325 AA.
AC   P14550; A8KAL8; D3DQ04; Q6IAZ4;
DE   RecName: Full=Alcohol dehydrogenase [NADP(+)];
DE            EC=1.1.1.2;
DE   AltName: Full=Aldehyde reductase;
DE   AltName: Full=Aldo-keto reductase family 1 member A1;
GN   Name=AKR1A1; Synonyms=ALDR1, ALR;
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0047939; F:L-glucuronate reductase activity; IEA:Ensembl.
DR   GO; GO:0046185; P:aldehyde catabolic process; IEA:Ensembl.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.
DR   GO; GO:0042840; P:D-glucuronate catabolic process; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:Ensembl.
//
ID   AK1BA_HUMAN             Reviewed;         316 AA.
AC   O60218; A4D1P1; O75890; Q6FHF3; Q8IWZ1;
DE   RecName: Full=Aldo-keto reductase family 1 member B10;
DE            EC=1.1.1.-;
DE   AltName: Full=ARL-1;
DE   AltName: Full=Aldose reductase-like;
DE   AltName: Full=Aldose reductase-related protein;
DE            Short=ARP;
DE            Short=hARP;
DE   AltName: Full=Small intestine reductase;
DE            Short=SI reductase;
GN   Name=AKR1B10; Synonyms=AKR1B11;
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.
DR   GO; GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.
DR   GO; GO:0047718; F:indanol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
//
ID   AK1BF_HUMAN             Reviewed;         344 AA.
AC   C9JRZ8; C9J3V2;
DE   RecName: Full=Aldo-keto reductase family 1 member B15;
DE            EC=1.1.1.-;
GN   Name=AKR1B15;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   AK1C1_HUMAN             Reviewed;         323 AA.
AC   Q04828; P52896; Q5SR15; Q7M4N2; Q9UCX2;
DE   RecName: Full=Aldo-keto reductase family 1 member C1;
DE            EC=1.1.1.-;
DE   AltName: Full=20-alpha-hydroxysteroid dehydrogenase;
DE            Short=20-alpha-HSD;
DE            EC=1.1.1.149;
DE   AltName: Full=Chlordecone reductase homolog HAKRC;
DE   AltName: Full=Dihydrodiol dehydrogenase 1/2;
DE            Short=DD1/DD2;
DE   AltName: Full=High-affinity hepatic bile acid-binding protein;
DE            Short=HBAB;
DE   AltName: Full=Indanol dehydrogenase;
DE            EC=1.1.1.112;
DE   AltName: Full=Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
DE            EC=1.3.1.20;
GN   Name=AKR1C1; Synonyms=DDH, DDH1;
DR   GO; GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.
DR   GO; GO:0047042; F:androsterone dehydrogenase (B-specific) activity; IDA:UniProtKB.
DR   GO; GO:0032052; F:bile acid binding; IDA:UniProtKB.
DR   GO; GO:0031406; F:carboxylic acid binding; IDA:UniProtKB.
DR   GO; GO:0047718; F:indanol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; TAS:UniProtKB.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0007586; P:digestion; IDA:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProt.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; TAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0046683; P:response to organophosphorus; IEP:UniProtKB.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB.
//
ID   AK1C2_HUMAN             Reviewed;         323 AA.
AC   P52895; A8K2N9; B4DKR9; Q14133; Q5SR16; Q7M4N1; Q96A71;
DE   RecName: Full=Aldo-keto reductase family 1 member C2;
DE            EC=1.-.-.-;
DE   AltName: Full=3-alpha-HSD3;
DE   AltName: Full=Chlordecone reductase homolog HAKRD;
DE   AltName: Full=Dihydrodiol dehydrogenase 2;
DE            Short=DD-2;
DE            Short=DD2;
DE   AltName: Full=Dihydrodiol dehydrogenase/bile acid-binding protein;
DE            Short=DD/BABP;
DE   AltName: Full=Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
DE            EC=1.3.1.20;
DE   AltName: Full=Type III 3-alpha-hydroxysteroid dehydrogenase;
DE            EC=1.1.1.357;
GN   Name=AKR1C2; Synonyms=DDH2;
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0032052; F:bile acid binding; IDA:UniProtKB.
DR   GO; GO:0031406; F:carboxylic acid binding; IDA:UniProtKB.
DR   GO; GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.
DR   GO; GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0007586; P:digestion; IDA:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.
DR   GO; GO:0034694; P:response to prostaglandin; IDA:UniProtKB.
DR   GO; GO:0008202; P:steroid metabolic process; IDA:UniProtKB.
//
ID   AK1C3_HUMAN             Reviewed;         323 AA.
AC   P42330; A8K2V0; Q5T2L1; Q96DJ1; Q96KI8; Q99530; Q9UCX1; Q9UII3;
AC   Q9UKL9;
DE   RecName: Full=Aldo-keto reductase family 1 member C3;
DE            EC=1.-.-.-;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase type 5;
DE            Short=17-beta-HSD 5;
DE   AltName: Full=3-alpha-HSD type II, brain;
DE   AltName: Full=3-alpha-hydroxysteroid dehydrogenase type 2;
DE            Short=3-alpha-HSD type 2;
DE            EC=1.1.1.357;
DE   AltName: Full=Chlordecone reductase homolog HAKRb;
DE   AltName: Full=Dihydrodiol dehydrogenase 3;
DE            Short=DD-3;
DE            Short=DD3;
DE   AltName: Full=Dihydrodiol dehydrogenase type I;
DE   AltName: Full=HA1753;
DE   AltName: Full=Indanol dehydrogenase;
DE            EC=1.1.1.112;
DE   AltName: Full=Prostaglandin F synthase;
DE            Short=PGFS;
DE            EC=1.1.1.188;
DE   AltName: Full=Testosterone 17-beta-dehydrogenase 5;
DE            EC=1.1.1.239;
DE            EC=1.1.1.64;
DE   AltName: Full=Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
DE            EC=1.3.1.20;
GN   Name=AKR1C3; Synonyms=DDH1, HSD17B5, KIAA0119, PGFS;
DR   GO; GO:0047020; F:15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.
DR   GO; GO:0047023; F:androsterone dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IDA:UniProtKB.
DR   GO; GO:0035410; F:dihydrotestosterone 17-beta-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0045550; F:geranylgeranyl reductase activity; IDA:UniProtKB.
DR   GO; GO:0047718; F:indanol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045703; F:ketoreductase activity; IDA:UniProtKB.
DR   GO; GO:0047086; F:ketosteroid monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0018636; F:phenanthrene 9,10-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0036131; F:prostaglandin D2 11-ketoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.
DR   GO; GO:0047017; F:prostaglandin-F synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0071384; P:cellular response to corticosteroid stimulus; IDA:UniProtKB.
DR   GO; GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.
DR   GO; GO:0071379; P:cellular response to prostaglandin stimulus; IDA:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEP:UniProtKB.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0016488; P:farnesol catabolic process; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0044259; P:multicellular organismal macromolecule metabolic process; IEP:UniProtKB.
DR   GO; GO:1900053; P:negative regulation of retinoic acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IEP:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000224; P:regulation of testosterone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0070293; P:renal absorption; NAS:UniProtKB.
DR   GO; GO:0007584; P:response to nutrient; IEP:UniProtKB.
DR   GO; GO:0034694; P:response to prostaglandin; IDA:UniProtKB.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IEP:UniProtKB.
DR   GO; GO:0061370; P:testosterone biosynthetic process; IMP:UniProtKB.
//
ID   AK1C4_HUMAN             Reviewed;         323 AA.
AC   P17516; Q5T6A3; Q8WW84; Q9NS54;
DE   RecName: Full=Aldo-keto reductase family 1 member C4;
DE            EC=1.1.1.-;
DE   AltName: Full=3-alpha-HSD1;
DE   AltName: Full=3-alpha-hydroxysteroid dehydrogenase type I;
DE            EC=1.1.1.357;
DE   AltName: Full=Chlordecone reductase;
DE            Short=CDR;
DE            EC=1.1.1.225;
DE   AltName: Full=Dihydrodiol dehydrogenase 4;
DE            Short=DD-4;
DE            Short=DD4;
DE   AltName: Full=HAKRA;
GN   Name=AKR1C4; Synonyms=CHDR;
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.
DR   GO; GO:0047023; F:androsterone dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0015125; F:bile acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0047743; F:chlordecone reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:ProtInc.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0071395; P:cellular response to jasmonic acid stimulus; IDA:UniProtKB.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
//
ID   AK1D1_HUMAN             Reviewed;         326 AA.
AC   P51857; A1L4P6; A8K060; B4DPN3; B4DPN8;
DE   RecName: Full=3-oxo-5-beta-steroid 4-dehydrogenase;
DE            EC=1.3.1.3;
DE   AltName: Full=Aldo-keto reductase family 1 member D1;
DE   AltName: Full=Delta(4)-3-ketosteroid 5-beta-reductase;
DE   AltName: Full=Delta(4)-3-oxosteroid 5-beta-reductase;
GN   Name=AKR1D1; Synonyms=SRD5B1;
DR   GO; GO:0047787; F:delta4-3-oxosteroid 5beta-reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005496; F:steroid binding; TAS:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; IDA:UniProtKB.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0008207; P:C21-steroid hormone metabolic process; IDA:UniProtKB.
DR   GO; GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.
DR   GO; GO:0007586; P:digestion; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AKA10_HUMAN             Reviewed;         662 AA.
AC   O43572; B2R650; Q96AJ7;
DE   RecName: Full=A-kinase anchor protein 10, mitochondrial;
DE            Short=AKAP-10;
DE   AltName: Full=Dual specificity A kinase-anchoring protein 2;
DE            Short=D-AKAP-2;
DE   AltName: Full=Protein kinase A-anchoring protein 10;
DE            Short=PRKA10;
DE   Flags: Precursor;
GN   Name=AKAP10;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008104; P:protein localization; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   AKA11_HUMAN             Reviewed;        1901 AA.
AC   Q9UKA4; O75124; Q9NUK7;
DE   RecName: Full=A-kinase anchor protein 11;
DE            Short=AKAP-11;
DE   AltName: Full=A-kinase anchor protein 220 kDa;
DE            Short=AKAP 220;
DE            Short=hAKAP220;
DE   AltName: Full=Protein kinase A-anchoring protein 11;
DE            Short=PRKA11;
GN   Name=AKAP11; Synonyms=AKAP220, KIAA0629;
DR   GO; GO:0051018; F:protein kinase A binding; TAS:ProtInc.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
//
ID   AKA12_HUMAN             Reviewed;        1782 AA.
AC   Q02952; O00310; O00498; Q4LE68; Q5SZ80; Q5TGN1; Q68D82; Q99970;
DE   RecName: Full=A-kinase anchor protein 12;
DE            Short=AKAP-12;
DE   AltName: Full=A-kinase anchor protein 250 kDa;
DE            Short=AKAP 250;
DE   AltName: Full=Gravin;
DE   AltName: Full=Myasthenia gravis autoantigen;
GN   Name=AKAP12; Synonyms=AKAP250;
DR   GO; GO:0008179; F:adenylate cyclase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051018; F:protein kinase A binding; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; IMP:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:InterPro.
//
ID   AKA28_HUMAN             Reviewed;         197 AA.
AC   Q86UN6; Q86UN4; Q86UN5;
DE   RecName: Full=A-kinase anchor protein 14;
DE            Short=AKAP-14;
DE   AltName: Full=A-kinase anchor protein 28 kDa;
DE            Short=AKAP 28;
DE   AltName: Full=Protein kinase A-anchoring protein 14;
DE            Short=PRKA14;
GN   Name=AKAP14; Synonyms=AKAP28;
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   AKA7A_HUMAN             Reviewed;         104 AA.
AC   O43687; A8K2K6; Q5TBR9; Q5TBS0; Q9HCZ8; Q9P0G4;
DE   RecName: Full=A-kinase anchor protein 7 isoforms alpha and beta;
DE            Short=AKAP-7 isoforms alpha and beta;
DE   AltName: Full=A-kinase anchor protein 18 kDa;
DE            Short=AKAP 18;
DE   AltName: Full=Protein kinase A-anchoring protein 7 isoforms alpha/beta;
DE            Short=PRKA7 isoforms alpha/beta;
GN   Name=AKAP7; Synonyms=AKAP15, AKAP18;
DR   GO; GO:0051018; F:protein kinase A binding; IDA:UniProtKB.
DR   GO; GO:0001508; P:action potential; IC:BHF-UCL.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:ProtInc.
DR   GO; GO:1902261; P:positive regulation of delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0008104; P:protein localization; IC:UniProtKB.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
//
ID   AKA7G_HUMAN             Reviewed;         348 AA.
AC   Q9P0M2; B4DUC3; Q9HCZ8;
DE   RecName: Full=A-kinase anchor protein 7 isoform gamma;
DE            Short=AKAP-7 isoform gamma;
DE   AltName: Full=A-kinase anchor protein 18 kDa;
DE            Short=AKAP 18;
DE   AltName: Full=Protein kinase A-anchoring protein 7 isoform gamma;
DE            Short=PRKA7 isoform gamma;
GN   Name=AKAP7; Synonyms=AKAP18;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; IDA:UniProtKB.
//
ID   AKAP1_HUMAN             Reviewed;         903 AA.
AC   Q92667; A8K8Q1; D3DTZ0; Q13320; Q9BW14;
DE   RecName: Full=A-kinase anchor protein 1, mitochondrial;
DE   AltName: Full=A-kinase anchor protein 149 kDa;
DE            Short=AKAP 149;
DE   AltName: Full=Dual specificity A-kinase-anchoring protein 1;
DE            Short=D-AKAP-1;
DE   AltName: Full=Protein kinase A-anchoring protein 1;
DE            Short=PRKA1;
DE   AltName: Full=Spermatid A-kinase anchor protein 84;
DE            Short=S-AKAP84;
DE   Flags: Precursor;
GN   Name=AKAP1; Synonyms=AKAP149, PRKA1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
//
ID   AKAP2_HUMAN             Reviewed;         859 AA.
AC   Q9Y2D5; B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26;
DE   RecName: Full=A-kinase anchor protein 2;
DE            Short=AKAP-2;
DE   AltName: Full=AKAP-KL;
DE   AltName: Full=Protein kinase A-anchoring protein 2;
DE            Short=PRKA2;
GN   Name=AKAP2; Synonyms=KIAA0920, PRKA2;
//
ID   AKAP3_HUMAN             Reviewed;         853 AA.
AC   O75969; O75945; Q86X01; Q9UM61;
DE   RecName: Full=A-kinase anchor protein 3;
DE            Short=AKAP-3;
DE   AltName: Full=A-kinase anchor protein 110 kDa;
DE            Short=AKAP 110;
DE   AltName: Full=Cancer/testis antigen 82;
DE            Short=CT82;
DE   AltName: Full=Fibrous sheath protein of 95 kDa;
DE            Short=FSP95;
DE   AltName: Full=Fibrousheathin I;
DE   AltName: Full=Fibrousheathin-1;
DE   AltName: Full=Protein kinase A-anchoring protein 3;
DE            Short=PRKA3;
DE   AltName: Full=Sperm oocyte-binding protein;
GN   Name=AKAP3; Synonyms=AKAP110, SOB1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051018; F:protein kinase A binding; TAS:ProtInc.
DR   GO; GO:0007340; P:acrosome reaction; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IEA:Ensembl.
//
ID   AKAP4_HUMAN             Reviewed;         854 AA.
AC   Q5JQC9; A0AV85; O60904; O95246; Q5JQD1; Q5JQD2; Q5JQD3;
DE   RecName: Full=A-kinase anchor protein 4;
DE            Short=AKAP-4;
DE   AltName: Full=A-kinase anchor protein 82 kDa;
DE            Short=AKAP 82;
DE            Short=hAKAP82;
DE   AltName: Full=Major sperm fibrous sheath protein;
DE            Short=HI;
DE   AltName: Full=Protein kinase A-anchoring protein 4;
DE            Short=PRKA4;
DE   Flags: Precursor;
GN   Name=AKAP4; Synonyms=AKAP82;
DR   GO; GO:0051018; F:protein kinase A binding; ISS:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
DR   GO; GO:0030317; P:sperm motility; IMP:UniProtKB.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IEA:Ensembl.
//
ID   AKAP5_HUMAN             Reviewed;         427 AA.
AC   P24588; A2RRB8;
DE   RecName: Full=A-kinase anchor protein 5;
DE            Short=AKAP-5;
DE   AltName: Full=A-kinase anchor protein 79 kDa;
DE            Short=AKAP 79;
DE   AltName: Full=H21;
DE   AltName: Full=cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein;
GN   Name=AKAP5; Synonyms=AKAP79;
DR   GO; GO:0008179; F:adenylate cyclase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051018; F:protein kinase A binding; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; IMP:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   AKAP6_HUMAN             Reviewed;        2319 AA.
AC   Q13023; A7E242; A7E2D4; O15028;
DE   RecName: Full=A-kinase anchor protein 6;
DE            Short=AKAP-6;
DE   AltName: Full=A-kinase anchor protein 100 kDa;
DE            Short=AKAP 100;
DE   AltName: Full=Protein kinase A-anchoring protein 6;
DE            Short=PRKA6;
DE   AltName: Full=mAKAP;
GN   Name=AKAP6; Synonyms=AKAP100, KIAA0311;
DR   GO; GO:0008179; F:adenylate cyclase binding; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0043495; F:protein anchor; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; ISS:BHF-UCL.
DR   GO; GO:0051018; F:protein kinase A binding; NAS:UniProtKB.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; ISS:BHF-UCL.
DR   GO; GO:0001508; P:action potential; IC:BHF-UCL.
DR   GO; GO:0019933; P:cAMP-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:BHF-UCL.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; ISS:BHF-UCL.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; ISS:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; ISS:BHF-UCL.
DR   GO; GO:0061051; P:positive regulation of cell growth involved in cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:1902261; P:positive regulation of delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0051533; P:positive regulation of NFAT protein import into nucleus; ISS:BHF-UCL.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0032514; P:positive regulation of protein phosphatase type 2B activity; ISS:BHF-UCL.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; ISS:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL.
DR   GO; GO:0006605; P:protein targeting; NAS:UniProtKB.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0010738; P:regulation of protein kinase A signaling; ISS:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IC:BHF-UCL.
//
ID   AKAP8_HUMAN             Reviewed;         692 AA.
AC   O43823;
DE   RecName: Full=A-kinase anchor protein 8;
DE            Short=AKAP-8;
DE   AltName: Full=A-kinase anchor protein 95 kDa;
DE            Short=AKAP 95;
GN   Name=AKAP8; Synonyms=AKAP95;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   AKAP9_HUMAN             Reviewed;        3911 AA.
AC   Q99996; A4D1F0; A4D1F2; A4D1F4; O14869; O43355; O94895; Q75N20;
AC   Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2;
DE   RecName: Full=A-kinase anchor protein 9;
DE            Short=AKAP-9;
DE   AltName: Full=A-kinase anchor protein 350 kDa;
DE            Short=AKAP 350;
DE            Short=hgAKAP 350;
DE   AltName: Full=A-kinase anchor protein 450 kDa;
DE            Short=AKAP 450;
DE   AltName: Full=AKAP 120-like protein;
DE   AltName: Full=Centrosome- and Golgi-localized PKN-associated protein;
DE            Short=CG-NAP;
DE   AltName: Full=Protein hyperion;
DE   AltName: Full=Protein kinase A-anchoring protein 9;
DE            Short=PRKA9;
DE   AltName: Full=Protein yotiao;
GN   Name=AKAP9; Synonyms=AKAP350, AKAP450, KIAA0803;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AKCL1_HUMAN             Reviewed;         129 AA.
AC   Q5T2L2; A6NF66; Q6ZN81;
DE   RecName: Full=Aldo-keto reductase family 1 member C-like protein 1;
DE            EC=1.1.1.-;
GN   Name=AKR1CL1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   AKCL2_HUMAN             Reviewed;         320 AA.
AC   Q96JD6; Q86Z16; Q86Z17; Q86Z18; Q9BU71;
DE   RecName: Full=1,5-anhydro-D-fructose reductase;
DE            Short=AF reductase;
DE            EC=1.1.1.263;
DE   AltName: Full=Aldo-keto reductase family 1 member C-like protein 2;
DE   AltName: Full=Aldo-keto reductase family 1 member E2;
DE   AltName: Full=LoopADR;
DE   AltName: Full=Testis-specific protein;
DE            Short=hTSP;
GN   Name=AKR1E2; Synonyms=AKR1CL2, AKRDC1;
DR   GO; GO:0050571; F:1,5-anhydro-D-fructose reductase activity; IEA:UniProtKB-EC.
//
ID   AKD1B_HUMAN             Reviewed;         528 AA.
AC   A6NHY2;
DE   RecName: Full=Ankyrin repeat and death domain-containing protein 1B;
GN   Name=ANKDD1B;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   AKD1A_HUMAN             Reviewed;         522 AA.
AC   Q495B1; Q495B2; Q495B3; Q8N7A0; Q8NBS5;
DE   RecName: Full=Ankyrin repeat and death domain-containing protein 1A;
GN   Name=ANKDD1A;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   AKIB1_HUMAN             Reviewed;        1089 AA.
AC   Q9P2G1; Q6GMS4; Q6P3S9; Q9NTD7; Q9NW49;
DE   RecName: Full=Ankyrin repeat and IBR domain-containing protein 1;
GN   Name=ANKIB1; Synonyms=KIAA1386;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   AKIP1_HUMAN             Reviewed;         210 AA.
AC   Q9NQ31; Q8NBS2; Q8TAC6; Q8TAD3; Q8TAE0;
DE   RecName: Full=A-kinase-interacting protein 1;
DE   AltName: Full=Breast cancer-associated gene 3 protein;
DE   AltName: Full=PKA-interacting protein;
DE   AltName: Full=Proline-rich protein BCA3;
GN   Name=AKIP1; Synonyms=BCA3, C11orf17;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Ensembl.
//
ID   AKIP_HUMAN              Reviewed;         199 AA.
AC   Q9NWT8; Q5TA36; Q8TBD3;
DE   RecName: Full=Aurora kinase A-interacting protein;
DE            Short=AURKA-interacting protein;
DE   AltName: Full=28S ribosomal protein S38, mitochondrial;
DE            Short=MRP-S38;
GN   Name=AURKAIP1; Synonyms=AIP, AKIP, MRPS38;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045839; P:negative regulation of mitosis; NAS:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:MGI.
//
ID   AKIR1_HUMAN             Reviewed;         192 AA.
AC   Q9H9L7; B4DZU6; Q0VDB3; Q53FK8;
DE   RecName: Full=Akirin-1;
GN   Name=AKIRIN1; Synonyms=C1orf108;
//
ID   AKIR2_HUMAN             Reviewed;         203 AA.
AC   Q53H80; Q9BQB1;
DE   RecName: Full=Akirin-2;
GN   Name=AKIRIN2; Synonyms=C6orf166;
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010950; P:positive regulation of endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AKNA_HUMAN              Reviewed;        1439 AA.
AC   Q7Z591; Q05BK5; Q5T535; Q5T536; Q5T537; Q64FX6; Q64FX7; Q64FX8;
AC   Q64FY2; Q6ZMK0; Q6ZNL2; Q6ZTX0; Q8TET1; Q8TF33; Q96RR9; Q9H7P7;
DE   RecName: Full=AT-hook-containing transcription factor;
GN   Name=AKNA; Synonyms=KIAA1968;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AKND1_HUMAN             Reviewed;         836 AA.
AC   Q5T1N1; B9EK62; Q5T1N0; Q8N990; Q8NCN9;
DE   RecName: Full=Protein AKNAD1;
GN   Name=AKNAD1; Synonyms=C1orf62;
//
ID   AKP13_HUMAN             Reviewed;        2813 AA.
AC   Q12802; Q14572; Q59FP6; Q86W90; Q8WXQ6; Q96JP6; Q96P79; Q9Y5T0;
AC   Q9Y5T6;
DE   RecName: Full=A-kinase anchor protein 13;
DE            Short=AKAP-13;
DE   AltName: Full=AKAP-Lbc;
DE   AltName: Full=Breast cancer nuclear receptor-binding auxiliary protein;
DE   AltName: Full=Guanine nucleotide exchange factor Lbc;
DE   AltName: Full=Human thyroid-anchoring protein 31;
DE   AltName: Full=Lymphoid blast crisis oncogene;
DE            Short=LBC oncogene;
DE   AltName: Full=Non-oncogenic Rho GTPase-specific GTP exchange factor;
DE   AltName: Full=Protein kinase A-anchoring protein 13;
DE            Short=PRKA13;
DE   AltName: Full=p47;
GN   Name=AKAP13; Synonyms=BRX, HT31, LBC;
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051168; P:nuclear export; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:GOC.
DR   GO; GO:0010611; P:regulation of cardiac muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:1900169; P:regulation of glucocorticoid mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   AKP8L_HUMAN             Reviewed;         646 AA.
AC   Q9ULX6; B4DJ74; B5BU90; O94792; Q96J58; Q9NRQ0; Q9UGM0;
DE   RecName: Full=A-kinase anchor protein 8-like;
DE            Short=AKAP8-like protein;
DE   AltName: Full=Helicase A-binding protein 95;
DE            Short=HAP95;
DE   AltName: Full=Homologous to AKAP95 protein;
DE            Short=HA95;
DE   AltName: Full=Neighbor of A-kinase-anchoring protein 95;
DE            Short=Neighbor of AKAP95;
GN   Name=AKAP8L; Synonyms=NAKAP, NAKAP95; ORFNames=HRIHFB2018;
DR   GO; GO:0017151; F:DEAD/H-box RNA helicase binding; TAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   AKT1_HUMAN              Reviewed;         480 AA.
AC   P31749; B2RAM5; Q9BWB6;
DE   RecName: Full=RAC-alpha serine/threonine-protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase B;
DE            Short=PKB;
DE   AltName: Full=Protein kinase B alpha;
DE            Short=PKB alpha;
DE   AltName: Full=Proto-oncogene c-Akt;
DE   AltName: Full=RAC-PK-alpha;
GN   Name=AKT1; Synonyms=PKB, RAC;
DR   GuidetoPHARMACOLOGY; 1479; -.
DR   GO; GO:0071889; F:14-3-3 protein binding; IPI:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; ISS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0016301; F:kinase activity; IDA:MGI.
DR   GO; GO:0030235; F:nitric-oxide synthase regulator activity; IMP:BHF-UCL.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006924; P:activation-induced cell death of T cells; IMP:MGI.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097194; P:execution phase of apoptosis; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0060709; P:glycogen cell differentiation involved in embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:BHF-UCL.
DR   GO; GO:0045792; P:negative regulation of cell size; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IMP:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:BHF-UCL.
DR   GO; GO:0031999; P:negative regulation of fatty acid beta-oxidation; IMP:BHF-UCL.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; NAS:BHF-UCL.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IMP:BHF-UCL.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; ISS:BHF-UCL.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:0010907; P:positive regulation of glucose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:Ensembl.
DR   GO; GO:1901976; P:regulation of cell cycle checkpoint; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0034405; P:response to fluid shear stress; IMP:BHF-UCL.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; TAS:ProtInc.
DR   GO; GO:0070141; P:response to UV-A; IDA:BHF-UCL.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IEA:Ensembl.
//
ID   AKT2_HUMAN              Reviewed;         481 AA.
AC   P31751; B2RBD8; Q05BV0; Q0VAN1; Q68GC0;
DE   RecName: Full=RAC-beta serine/threonine-protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase Akt-2;
DE   AltName: Full=Protein kinase B beta;
DE            Short=PKB beta;
DE   AltName: Full=RAC-PK-beta;
GN   Name=AKT2;
DR   GuidetoPHARMACOLOGY; 1480; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016301; F:kinase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032859; P:activation of Ral GTPase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; TAS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:2000147; P:positive regulation of cell motility; IMP:BHF-UCL.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0010907; P:positive regulation of glucose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; TAS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   AKT3_HUMAN              Reviewed;         479 AA.
AC   Q9Y243; Q0VAA6; Q5VTI1; Q5VTI2; Q96QV3; Q9UFP5;
DE   RecName: Full=RAC-gamma serine/threonine-protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase Akt-3;
DE   AltName: Full=Protein kinase B gamma;
DE            Short=PKB gamma;
DE   AltName: Full=RAC-PK-gamma;
DE   AltName: Full=STK-2;
GN   Name=AKT3; Synonyms=PKBG;
DR   GuidetoPHARMACOLOGY; 2286; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
//
ID   AKTIP_HUMAN             Reviewed;         292 AA.
AC   Q9H8T0; Q503B1; Q53H38;
DE   RecName: Full=AKT-interacting protein;
DE   AltName: Full=Ft1;
DE   AltName: Full=Fused toes protein homolog;
GN   Name=AKTIP; Synonyms=FTS;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:MGI.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AKTS1_HUMAN             Reviewed;         256 AA.
AC   Q96B36; A8MTQ1; B2RE93; J3KPM3; Q96BI4; Q96IK7; Q96NG2; Q9BWR5;
DE   RecName: Full=Proline-rich AKT1 substrate 1;
DE   AltName: Full=40 kDa proline-rich AKT substrate;
GN   Name=AKT1S1; Synonyms=PRAS40;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045792; P:negative regulation of cell size; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
//
ID   AL14E_HUMAN             Reviewed;         260 AA.
AC   Q8N8R7; Q5HYH9;
DE   RecName: Full=ARL14 effector protein;
DE   AltName: Full=ARF7 effector protein;
GN   Name=ARL14EP; Synonyms=ARF7EP, C11orf46;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   AL1A1_HUMAN             Reviewed;         501 AA.
AC   P00352; O00768; Q5SYR1;
DE   RecName: Full=Retinal dehydrogenase 1;
DE            Short=RALDH 1;
DE            Short=RalDH1;
DE            EC=1.2.1.36;
DE   AltName: Full=ALDH-E1;
DE   AltName: Full=ALHDII;
DE   AltName: Full=Aldehyde dehydrogenase family 1 member A1;
DE   AltName: Full=Aldehyde dehydrogenase, cytosolic;
GN   Name=ALDH1A1; Synonyms=ALDC, ALDH1, PUMB1;
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; EXP:Reactome.
DR   GO; GO:0005497; F:androgen binding; TAS:ProtInc.
DR   GO; GO:0005099; F:Ras GTPase activator activity; TAS:UniProtKB.
DR   GO; GO:0001758; F:retinal dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.
DR   GO; GO:0006069; P:ethanol oxidation; TAS:Reactome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; TAS:GOC.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   AL1A2_HUMAN             Reviewed;         518 AA.
AC   O94788; B3KY52; B4DZR2; F5H2Y9; H0YM00; Q2PJS6; Q8NHQ4; Q9UBR8;
AC   Q9UFY0;
DE   RecName: Full=Retinal dehydrogenase 2;
DE            Short=RALDH 2;
DE            Short=RalDH2;
DE            EC=1.2.1.36;
DE   AltName: Full=Aldehyde dehydrogenase family 1 member A2;
DE   AltName: Full=Retinaldehyde-specific dehydrogenase type 2;
DE            Short=RALDH(II);
GN   Name=ALDH1A2; Synonyms=RALDH2;
DR   GO; GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; ISS:UniProtKB.
DR   GO; GO:0016918; F:retinal binding; ISS:UniProtKB.
DR   GO; GO:0001758; F:retinal dehydrogenase activity; ISS:UniProtKB.
DR   GO; GO:0042904; P:9-cis-retinoic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0009855; P:determination of bilateral symmetry; IEA:Ensembl.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060324; P:face development; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0007494; P:midgut development; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IMP:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0001936; P:regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IDA:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0042574; P:retinal metabolic process; IEA:Ensembl.
DR   GO; GO:0042573; P:retinoic acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0035799; P:ureter maturation; IEA:Ensembl.
DR   GO; GO:0006776; P:vitamin A metabolic process; NAS:UniProtKB.
//
ID   AL1A3_HUMAN             Reviewed;         512 AA.
AC   P47895; Q6NT64;
DE   RecName: Full=Aldehyde dehydrogenase family 1 member A3;
DE            EC=1.2.1.5;
DE   AltName: Full=Aldehyde dehydrogenase 6;
DE   AltName: Full=Retinaldehyde dehydrogenase 3;
DE            Short=RALDH-3;
DE            Short=RalDH3;
GN   Name=ALDH1A3; Synonyms=ALDH6;
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:Ensembl.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IDA:UniProtKB.
DR   GO; GO:0070403; F:NAD+ binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0070324; F:thyroid hormone binding; IEA:Ensembl.
DR   GO; GO:0048048; P:embryonic eye morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060324; P:face development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0021768; P:nucleus accumbens development; IEA:Ensembl.
DR   GO; GO:0060166; P:olfactory pit development; IEA:Ensembl.
DR   GO; GO:0002072; P:optic cup morphogenesis involved in camera-type eye development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:UniProtKB.
DR   GO; GO:0002138; P:retinoic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0060013; P:righting reflex; IEA:Ensembl.
//
ID   AL1B1_HUMAN             Reviewed;         517 AA.
AC   P30837; B2R8F0; Q8WX76; Q9BV45;
DE   RecName: Full=Aldehyde dehydrogenase X, mitochondrial;
DE            EC=1.2.1.3;
DE   AltName: Full=Aldehyde dehydrogenase 5;
DE   AltName: Full=Aldehyde dehydrogenase family 1 member B1;
DE   Flags: Precursor;
GN   Name=ALDH1B1; Synonyms=ALDH5, ALDHX;
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0006068; P:ethanol catabolic process; IEA:UniProtKB-UniPathway.
//
ID   AL1L1_HUMAN             Reviewed;         902 AA.
AC   O75891; B4DG36; E9PBX3; Q68CS1;
DE   RecName: Full=Cytosolic 10-formyltetrahydrofolate dehydrogenase;
DE            Short=10-FTHFDH;
DE            Short=FDH;
DE            EC=1.5.1.6;
DE   AltName: Full=Aldehyde dehydrogenase family 1 member L1;
GN   Name=ALDH1L1; Synonyms=FTHFD;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0009258; P:10-formyltetrahydrofolate catabolic process; TAS:ProtInc.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
//
ID   AL1L2_HUMAN             Reviewed;         923 AA.
AC   Q3SY69; Q3SY68; Q68D62; Q6AI55; Q8N922;
DE   RecName: Full=Mitochondrial 10-formyltetrahydrofolate dehydrogenase;
DE            Short=Mitochondrial 10-FTHFDH;
DE            Short=mtFDH;
DE            EC=1.5.1.6;
DE   AltName: Full=Aldehyde dehydrogenase family 1 member L2;
GN   Name=ALDH1L2;
DR   GO; GO:0016155; F:formyltetrahydrofolate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0009258; P:10-formyltetrahydrofolate catabolic process; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
//
ID   AL2CL_HUMAN             Reviewed;         953 AA.
AC   Q60I27; Q32MA1; Q6AI56; Q6ZNC5; Q6ZNC7; Q6ZTL4; Q86YD2; Q8N9U1;
AC   Q8NAL7;
DE   RecName: Full=ALS2 C-terminal-like protein;
GN   Name=ALS2CL;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:MGI.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0007032; P:endosome organization; IGI:MGI.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
//
ID   AL2SA_HUMAN             Reviewed;         623 AA.
AC   Q53TS8; C9IZH7; E9PGG4; Q8NCN6; Q96LN4;
DE   RecName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein;
GN   Name=ALS2CR11;
//
ID   AL2SB_HUMAN             Reviewed;         445 AA.
AC   Q96Q35; G5E9S3; Q53TT6; Q8N1B6;
DE   RecName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein;
GN   Name=ALS2CR12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043087; P:regulation of GTPase activity; NAS:UniProtKB.
//
ID   AL3A1_HUMAN             Reviewed;         453 AA.
AC   P30838; A8K828; Q9BT37;
DE   RecName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring;
DE            EC=1.2.1.5;
DE   AltName: Full=ALDHIII;
DE   AltName: Full=Aldehyde dehydrogenase 3;
DE   AltName: Full=Aldehyde dehydrogenase family 3 member A1;
GN   Name=ALDH3A1; Synonyms=ALDH3;
DR   GO; GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   AL3A2_HUMAN             Reviewed;         485 AA.
AC   P51648; Q6I9T3; Q93011; Q96J37;
DE   RecName: Full=Fatty aldehyde dehydrogenase;
DE            EC=1.2.1.3;
DE   AltName: Full=Aldehyde dehydrogenase 10;
DE   AltName: Full=Aldehyde dehydrogenase family 3 member A2;
DE   AltName: Full=Microsomal aldehyde dehydrogenase;
GN   Name=ALDH3A2; Synonyms=ALDH10, FALDH;
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro.
DR   GO; GO:0046577; F:long-chain-alcohol oxidase activity; IDA:UniProtKB.
DR   GO; GO:0050061; F:long-chain-aldehyde dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0052814; F:medium-chain-aldehyde dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IMP:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; IMP:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0007422; P:peripheral nervous system development; IMP:UniProtKB.
DR   GO; GO:0033306; P:phytol metabolic process; IMP:UniProtKB.
DR   GO; GO:0006714; P:sesquiterpenoid metabolic process; IDA:UniProtKB.
//
ID   AL3B1_HUMAN             Reviewed;         468 AA.
AC   P43353; A3FMP9; Q53XL5; Q8N515; Q96CK8;
DE   RecName: Full=Aldehyde dehydrogenase family 3 member B1;
DE            EC=1.2.1.5;
DE   AltName: Full=Aldehyde dehydrogenase 7;
DE   Flags: Precursor;
GN   Name=ALDH3B1; Synonyms=ALDH7;
DR   GO; GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IDA:MGI.
DR   GO; GO:0006066; P:alcohol metabolic process; TAS:ProtInc.
DR   GO; GO:0046185; P:aldehyde catabolic process; IDA:MGI.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:MGI.
DR   GO; GO:0006068; P:ethanol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:MGI.
//
ID   AL3B2_HUMAN             Reviewed;         385 AA.
AC   P48448; Q53Y98; Q8NAL5; Q96IB2;
DE   RecName: Full=Aldehyde dehydrogenase family 3 member B2;
DE            EC=1.2.1.5;
DE   AltName: Full=Aldehyde dehydrogenase 8;
GN   Name=ALDH3B2; Synonyms=ALDH8;
DR   GO; GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0006066; P:alcohol metabolic process; TAS:ProtInc.
DR   GO; GO:0006068; P:ethanol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
//
ID   AL4A1_HUMAN             Reviewed;         563 AA.
AC   P30038; A8K1Q7; B4DGE4; D2D4A3; Q16882; Q53HU4; Q5JNV6; Q8IZ38;
AC   Q96IF0; Q9UDI6;
DE   RecName: Full=Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial;
DE            Short=P5C dehydrogenase;
DE            EC=1.2.1.88;
DE   AltName: Full=Aldehyde dehydrogenase family 4 member A1;
DE   AltName: Full=L-glutamate gamma-semialdehyde dehydrogenase;
DE   Flags: Precursor;
GN   Name=ALDH4A1; Synonyms=ALDH4, P5CDH;
DR   GO; GO:0003842; F:1-pyrroline-5-carboxylate dehydrogenase activity; EXP:Reactome.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019470; P:4-hydroxyproline catabolic process; TAS:BHF-UCL.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006561; P:proline biosynthetic process; IEA:InterPro.
DR   GO; GO:0006562; P:proline catabolic process; TAS:Reactome.
DR   GO; GO:0010133; P:proline catabolic process to glutamate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006560; P:proline metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AL5AP_HUMAN             Reviewed;         161 AA.
AC   P20292; Q5VV04;
DE   RecName: Full=Arachidonate 5-lipoxygenase-activating protein;
DE   AltName: Full=FLAP;
DE   AltName: Full=MK-886-binding protein;
GN   Name=ALOX5AP; Synonyms=FLAP;
DR   GO; GO:0050544; F:arachidonic acid binding; IDA:UniProtKB.
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0002540; P:leukotriene production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:2001300; P:lipoxin metabolic process; TAS:Reactome.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IPI:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AL7A1_HUMAN             Reviewed;         539 AA.
AC   P49419; B2R669; B4DIC7; B4DMA0; E7EPT3; O14619; Q6IPU8; Q9BUL4;
DE   RecName: Full=Alpha-aminoadipic semialdehyde dehydrogenase;
DE            Short=Alpha-AASA dehydrogenase;
DE            EC=1.2.1.31;
DE   AltName: Full=Aldehyde dehydrogenase family 7 member A1;
DE            EC=1.2.1.3;
DE   AltName: Full=Antiquitin-1;
DE   AltName: Full=Betaine aldehyde dehydrogenase;
DE            EC=1.2.1.8;
DE   AltName: Full=Delta1-piperideine-6-carboxylate dehydrogenase;
DE            Short=P6c dehydrogenase;
DE   Flags: Precursor;
GN   Name=ALDH7A1; Synonyms=ATQ1;
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; ISS:UniProtKB.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004043; F:L-aminoadipate-semialdehyde dehydrogenase activity; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; ISS:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019285; P:glycine betaine biosynthetic process from choline; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AL8A1_HUMAN             Reviewed;         487 AA.
AC   Q9H2A2; B7Z521; O60793; Q24JS9; Q53GT3; Q5TI80;
DE   RecName: Full=Aldehyde dehydrogenase family 8 member A1;
DE            EC=1.2.1.-;
DE   AltName: Full=Aldehyde dehydrogenase 12;
GN   Name=ALDH8A1; Synonyms=ALDH12;
DR   GO; GO:0001758; F:retinal dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0042904; P:9-cis-retinoic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:UniProtKB.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IDA:UniProtKB.
//
ID   AL9A1_HUMAN             Reviewed;         494 AA.
AC   P49189; B2R6X1; Q5VV90; Q6LCL1; Q9NZT7;
DE   RecName: Full=4-trimethylaminobutyraldehyde dehydrogenase;
DE            Short=TMABADH;
DE            EC=1.2.1.47;
DE   AltName: Full=Aldehyde dehydrogenase E3 isozyme;
DE   AltName: Full=Aldehyde dehydrogenase family 9 member A1;
DE            EC=1.2.1.3;
DE   AltName: Full=Gamma-aminobutyraldehyde dehydrogenase;
DE            EC=1.2.1.19;
DE   AltName: Full=R-aminobutyraldehyde dehydrogenase;
GN   Name=ALDH9A1; Synonyms=ALDH4, ALDH7, ALDH9;
DR   GO; GO:0033737; F:1-pyrroline dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004028; F:3-chloroallyl aldehyde dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0047105; F:4-trimethylammoniobutyraldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0043176; F:amine binding; IEA:Ensembl.
DR   GO; GO:0019145; F:aminobutyraldehyde dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0045329; P:carnitine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042445; P:hormone metabolic process; TAS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ALAT1_HUMAN             Reviewed;         496 AA.
AC   P24298; B0YJ18; D3DWM7; P78398; Q93076;
DE   RecName: Full=Alanine aminotransferase 1;
DE            Short=ALT1;
DE            EC=2.6.1.2;
DE   AltName: Full=Glutamate pyruvate transaminase 1;
DE            Short=GPT 1;
DE   AltName: Full=Glutamic--alanine transaminase 1;
DE   AltName: Full=Glutamic--pyruvic transaminase 1;
GN   Name=GPT; Synonyms=AAT1, GPT1;
DR   GO; GO:0004021; F:L-alanine:2-oxoglutarate aminotransferase activity; NAS:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ALAT2_HUMAN             Reviewed;         523 AA.
AC   Q8TD30; Q8N9E2;
DE   RecName: Full=Alanine aminotransferase 2;
DE            Short=ALT2;
DE            EC=2.6.1.2;
DE   AltName: Full=Glutamate pyruvate transaminase 2;
DE            Short=GPT 2;
DE   AltName: Full=Glutamic--alanine transaminase 2;
DE   AltName: Full=Glutamic--pyruvic transaminase 2;
GN   Name=GPT2; Synonyms=AAT2, ALT2;
DR   GO; GO:0004021; F:L-alanine:2-oxoglutarate aminotransferase activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IDA:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042853; P:L-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042851; P:L-alanine metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ALBU_HUMAN              Reviewed;         609 AA.
AC   P02768; O95574; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0;
AC   Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0;
DE   RecName: Full=Serum albumin;
DE   Flags: Precursor;
GN   Name=ALB;
GN   ORFNames=GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675,
GN   UNQ696/PRO1341;
DR   GO; GO:0016209; F:antioxidant activity; NAS:UniProtKB.
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0005507; F:copper ion binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0005504; F:fatty acid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0015643; F:toxic substance binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0009267; P:cellular response to starvation; IDA:UniProtKB.
DR   GO; GO:0019836; P:hemolysis by symbiont of host erythrocytes; IDA:UniProtKB.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0051659; P:maintenance of mitochondrion location; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0046010; P:positive regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0046689; P:response to mercury ion; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0070541; P:response to platinum ion; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:UniProtKB.
//
ID   ALDH2_HUMAN             Reviewed;         517 AA.
AC   P05091; B4DW54; E7EUE5; Q03639; Q6IB13; Q6IV71;
DE   RecName: Full=Aldehyde dehydrogenase, mitochondrial;
DE            EC=1.2.1.3;
DE   AltName: Full=ALDH class 2;
DE   AltName: Full=ALDH-E2;
DE   AltName: Full=ALDHI;
DE   Flags: Precursor;
GN   Name=ALDH2; Synonyms=ALDM;
DR   GuidetoPHARMACOLOGY; 2595; -.
DR   GO; GO:0004029; F:aldehyde dehydrogenase (NAD) activity; EXP:Reactome.
DR   GO; GO:0004030; F:aldehyde dehydrogenase [NAD(P)+] activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0006066; P:alcohol metabolic process; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006068; P:ethanol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006069; P:ethanol oxidation; TAS:Reactome.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ALDOA_HUMAN             Reviewed;         364 AA.
AC   P04075; B4DXI7; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2;
DE   RecName: Full=Fructose-bisphosphate aldolase A;
DE            EC=4.1.2.13;
DE   AltName: Full=Lung cancer antigen NY-LU-1;
DE   AltName: Full=Muscle-type aldolase;
GN   Name=ALDOA; Synonyms=ALDA;
DR   GO; GO:0003779; F:actin binding; TAS:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL.
DR   GO; GO:0070061; F:fructose binding; IDA:BHF-UCL.
DR   GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; TAS:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015631; F:tubulin binding; TAS:BHF-UCL.
DR   GO; GO:0007015; P:actin filament organization; TAS:BHF-UCL.
DR   GO; GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030388; P:fructose 1,6-bisphosphate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006000; P:fructose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IMP:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IMP:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006941; P:striated muscle contraction; IMP:BHF-UCL.
//
ID   ALDOB_HUMAN             Reviewed;         364 AA.
AC   P05062; Q13741; Q13742; Q5T7D6;
DE   RecName: Full=Fructose-bisphosphate aldolase B;
DE            EC=4.1.2.13;
DE   AltName: Full=Liver-type aldolase;
GN   Name=ALDOB; Synonyms=ALDB;
DR   GO; GO:0051117; F:ATPase binding; IDA:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL.
DR   GO; GO:0070061; F:fructose binding; IMP:BHF-UCL.
DR   GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030388; P:fructose 1,6-bisphosphate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006001; P:fructose catabolic process; TAS:Reactome.
DR   GO; GO:0006000; P:fructose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IDA:BHF-UCL.
DR   GO; GO:0006116; P:NADH oxidation; IDA:BHF-UCL.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IGI:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; IGI:BHF-UCL.
//
ID   ALDOC_HUMAN             Reviewed;         364 AA.
AC   P09972; B2R5R3; Q3SYL3; Q6FH94; Q6P0L5;
DE   RecName: Full=Fructose-bisphosphate aldolase C;
DE            EC=4.1.2.13;
DE   AltName: Full=Brain-type aldolase;
GN   Name=ALDOC; Synonyms=ALDC;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL.
DR   GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0030388; P:fructose 1,6-bisphosphate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006000; P:fructose metabolic process; TAS:ProtInc.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ALDR_HUMAN              Reviewed;         316 AA.
AC   P15121; B2R8N3; Q5U031; Q6FGA4; Q6ICP2; Q9BS21; Q9UCI9;
DE   RecName: Full=Aldose reductase;
DE            Short=AR;
DE            EC=1.1.1.21;
DE   AltName: Full=Aldehyde reductase;
DE   AltName: Full=Aldo-keto reductase family 1 member B1;
GN   Name=AKR1B1; Synonyms=ALDR1;
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0043795; F:glyceraldehyde oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   ALEX_HUMAN              Reviewed;         626 AA.
AC   P84996; A2A2S4;
DE   RecName: Full=Protein ALEX;
DE   AltName: Full=Alternative gene product encoded by XL-exon;
GN   Name=GNAS; Synonyms=GNAS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0060348; P:bone development; IMP:UniProt.
DR   GO; GO:0050890; P:cognition; IMP:UniProt.
DR   GO; GO:0048589; P:developmental growth; IMP:UniProt.
DR   GO; GO:0060789; P:hair follicle placode formation; IMP:UniProt.
DR   GO; GO:0070527; P:platelet aggregation; IMP:UniProt.
//
ID   ALG11_HUMAN             Reviewed;         492 AA.
AC   Q2TAA5; A5PLP3; B4DKW9; Q5TAN9; Q6DKI6; Q96FI7;
DE   RecName: Full=GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase;
DE            EC=2.4.1.131;
DE   AltName: Full=Asparagine-linked glycosylation protein 11 homolog;
DE   AltName: Full=Glycolipid 2-alpha-mannosyltransferase;
GN   Name=ALG11; Synonyms=GT8;
DR   GO; GO:0004377; F:GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG12_HUMAN             Reviewed;         488 AA.
AC   Q9BV10; A6PWM1; Q4KMH4; Q8NG10; Q96AA4;
DE   RecName: Full=Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase;
DE            EC=2.4.1.260;
DE   AltName: Full=Asparagine-linked glycosylation protein 12 homolog;
DE            Short=hALG12;
DE   AltName: Full=Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase;
DE   AltName: Full=Mannosyltransferase ALG12 homolog;
DE   AltName: Full=Membrane protein SB87;
GN   Name=ALG12; ORFNames=PP14673;
DR   GO; GO:0000009; F:alpha-1,6-mannosyltransferase activity; IC:UniProtKB.
DR   GO; GO:0052917; F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IDA:MGI.
DR   GO; GO:0097502; P:mannosylation; IC:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IGI:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG13_HUMAN             Reviewed;        1137 AA.
AC   Q9NP73; B1AKD6; B1AKM1; B2R5L5; B7Z6J0; B7Z804; B7Z847; B7Z9A8;
AC   B7ZAJ1; B7ZB57; Q17RC3; Q5JXY9; Q9H5U8;
DE   RecName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13;
DE            EC=2.4.1.141;
DE            EC=3.4.19.12;
DE   AltName: Full=Asparagine-linked glycosylation 13 homolog;
DE   AltName: Full=Glycosyltransferase 28 domain-containing protein 1;
DE   AltName: Full=UDP-N-acetylglucosamine transferase subunit ALG13 homolog;
GN   Name=ALG13; Synonyms=CXorf45, GLT28D1; ORFNames=MDS031;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004577; F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG14_HUMAN             Reviewed;         216 AA.
AC   Q96F25; A8K030;
DE   RecName: Full=UDP-N-acetylglucosamine transferase subunit ALG14 homolog;
GN   Name=ALG14;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG1L_HUMAN             Reviewed;         187 AA.
AC   Q6GMV1; D3DNA5;
DE   RecName: Full=Putative glycosyltransferase ALG1-like;
DE            EC=2.4.1.-;
GN   Name=ALG1L;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   ALG1_HUMAN              Reviewed;         464 AA.
AC   Q9BT22; Q6UVZ9; Q8N5Y4; Q9P2Y2;
DE   RecName: Full=Chitobiosyldiphosphodolichol beta-mannosyltransferase;
DE            EC=2.4.1.142;
DE   AltName: Full=Asparagine-linked glycosylation protein 1 homolog;
DE   AltName: Full=Beta-1,4-mannosyltransferase;
DE   AltName: Full=GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase;
DE   AltName: Full=GDP-mannose-dolichol diphosphochitobiose mannosyltransferase;
DE   AltName: Full=Mannosyltransferase-1;
DE            Short=MT-1;
DE            Short=hMat-1;
GN   Name=ALG1; Synonyms=HMAT1, HMT1; ORFNames=PSEC0061, UNQ861/PRO1870;
DR   GO; GO:0004578; F:chitobiosyldiphosphodolichol beta-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000030; F:mannosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0097502; P:mannosylation; TAS:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG2_HUMAN              Reviewed;         416 AA.
AC   Q9H553; A2A2Y0; Q8NBX2; Q8NC39;
DE   RecName: Full=Alpha-1,3/1,6-mannosyltransferase ALG2;
DE            EC=2.4.1.132;
DE            EC=2.4.1.257;
DE   AltName: Full=Asparagine-linked glycosylation protein 2 homolog;
DE   AltName: Full=GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase;
DE   AltName: Full=GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase;
DE   AltName: Full=GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase;
GN   Name=ALG2; ORFNames=UNQ666/PRO1298;
DR   GO; GO:0000033; F:alpha-1,3-mannosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IMP:UniProtKB.
DR   GO; GO:0004378; F:GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043495; F:protein anchor; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IGI:UniProtKB.
DR   GO; GO:0097502; P:mannosylation; IDA:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0033577; P:protein glycosylation in endoplasmic reticulum; IGI:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
//
ID   ALG3_HUMAN              Reviewed;         438 AA.
AC   Q92685; A8JZZ6; Q9BT71;
DE   RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase;
DE            EC=2.4.1.258;
DE   AltName: Full=Asparagine-linked glycosylation protein 3 homolog;
DE   AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase;
DE   AltName: Full=Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase;
DE   AltName: Full=Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase;
DE   AltName: Full=Not56-like protein;
GN   Name=ALG3; Synonyms=NOT, NOT56L;
DR   GO; GO:0000033; F:alpha-1,3-mannosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0052925; F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0097502; P:mannosylation; IDA:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; NAS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG5_HUMAN              Reviewed;         324 AA.
AC   Q9Y673; B4DR37; Q5TBA6;
DE   RecName: Full=Dolichyl-phosphate beta-glucosyltransferase;
DE            Short=DolP-glucosyltransferase;
DE            EC=2.4.1.117;
DE   AltName: Full=Asparagine-linked glycosylation protein 5 homolog;
GN   Name=ALG5; ORFNames=HSPC149;
DR   GO; GO:0004581; F:dolichyl-phosphate beta-glucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004576; F:oligosaccharyl transferase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG6_HUMAN              Reviewed;         507 AA.
AC   Q9Y672; B3KMU2; Q5SXR9; Q9H3I0;
DE   RecName: Full=Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase;
DE            EC=2.4.1.267;
DE   AltName: Full=Asparagine-linked glycosylation protein 6 homolog;
DE   AltName: Full=Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase;
DE   AltName: Full=Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase;
GN   Name=ALG6; ORFNames=My046;
DR   GO; GO:0046527; F:glucosyltransferase activity; IDA:MGI.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IGI:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG8_HUMAN              Reviewed;         526 AA.
AC   Q9BVK2; A6NDW6; O60860;
DE   RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase;
DE            EC=2.4.1.265;
DE   AltName: Full=Asparagine-linked glycosylation protein 8 homolog;
DE   AltName: Full=Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase;
DE   AltName: Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase;
GN   Name=ALG8; ORFNames=HUSSY-02;
DR   GO; GO:0000033; F:alpha-1,3-mannosyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0097502; P:mannosylation; IMP:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IMP:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALG9_HUMAN              Reviewed;         611 AA.
AC   Q9H6U8; Q6ZMD5; Q7Z4R4; Q96GS7; Q96PB9; Q9H068;
DE   RecName: Full=Alpha-1,2-mannosyltransferase ALG9;
DE            EC=2.4.1.259;
DE            EC=2.4.1.261;
DE   AltName: Full=Asparagine-linked glycosylation protein 9 homolog;
DE   AltName: Full=Disrupted in bipolar disorder protein 1;
DE   AltName: Full=Dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase;
DE   AltName: Full=Dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase;
GN   Name=ALG9; Synonyms=DIBD1;
DR   GO; GO:0052926; F:dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052918; F:dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   ALKB1_HUMAN             Reviewed;         389 AA.
AC   Q13686; Q8TAU1; Q9ULA7;
DE   RecName: Full=Alkylated DNA repair protein alkB homolog 1;
DE            EC=1.14.11.33;
DE   AltName: Full=Alpha-ketoglutarate-dependent dioxygenase ABH1;
DE   AltName: Full=DNA lyase ABH1;
DE            EC=4.2.99.18;
DE   AltName: Full=DNA oxidative demethylase ALKBH1;
GN   Name=ALKBH1; Synonyms=ABH, ABH1, ALKBH;
DR   GO; GO:0042056; F:chemoattractant activity; IEA:Ensembl.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0070579; F:methylcytosine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:UniProtKB.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0042245; P:RNA repair; IDA:UniProtKB.
//
ID   ALKB2_HUMAN             Reviewed;         261 AA.
AC   Q6NS38; A4PET2; Q5XLE3;
DE   RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2;
DE            EC=1.14.11.33;
DE   AltName: Full=Alkylated DNA repair protein alkB homolog 2;
DE   AltName: Full=DNA oxidative demethylase ALKBH2;
DE   AltName: Full=Oxy DC1;
GN   Name=ALKBH2; Synonyms=ABH2;
DR   GO; GO:0051747; F:cytosine C-5 DNA demethylase activity; IDA:UniProtKB.
DR   GO; GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0080111; P:DNA demethylation; TAS:BHF-UCL.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0070989; P:oxidative demethylation; TAS:BHF-UCL.
DR   GO; GO:0035511; P:oxidative DNA demethylation; IDA:UniProtKB.
//
ID   ALKB3_HUMAN             Reviewed;         286 AA.
AC   Q96Q83; A6NDJ1; Q3SYI0; Q6NX57; Q96BU8;
DE   RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3;
DE            EC=1.14.11.-;
DE   AltName: Full=Alkylated DNA repair protein alkB homolog 3;
DE   AltName: Full=DEPC-1;
DE   AltName: Full=Prostate cancer antigen 1;
GN   Name=ALKBH3; Synonyms=ABH3, DEPC1;
DR   GO; GO:0051747; F:cytosine C-5 DNA demethylase activity; IEA:Ensembl.
DR   GO; GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IDA:UniProtKB.
//
ID   ALKB4_HUMAN             Reviewed;         302 AA.
AC   Q9NXW9; Q53H92; Q9H6A4;
DE   RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4;
DE            EC=1.14.11.-;
DE   AltName: Full=Alkylated DNA repair protein alkB homolog 4;
GN   Name=ALKBH4; Synonyms=ABH4;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0032451; F:demethylase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.
DR   GO; GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.
DR   GO; GO:0036090; P:cleavage furrow ingression; IMP:UniProtKB.
DR   GO; GO:0006482; P:protein demethylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ALKB5_HUMAN             Reviewed;         394 AA.
AC   Q6P6C2; B4DVJ4; D3DXC6; Q9NXD6;
DE   RecName: Full=RNA demethylase ALKBH5;
DE            EC=1.14.11.-;
DE   AltName: Full=Alkylated DNA repair protein alkB homolog 5;
DE   AltName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5;
GN   Name=ALKBH5; Synonyms=ABH5, OFOXD1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035515; F:oxidative RNA demethylase activity; IDA:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IMP:UniProtKB.
DR   GO; GO:0035553; P:oxidative single-stranded RNA demethylation; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   ALKB6_HUMAN             Reviewed;         238 AA.
AC   Q3KRA9; A5LGM8; A6NLP1; A8MU96;
DE   RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6;
DE            EC=1.14.11.-;
DE   AltName: Full=Alkylated DNA repair protein alkB homolog 6;
GN   Name=ALKBH6; Synonyms=ABH6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   ALKB7_HUMAN             Reviewed;         221 AA.
AC   Q9BT30; B2R4U9; Q53FF3;
DE   RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial;
DE            EC=1.14.11.-;
DE   AltName: Full=Alkylated DNA repair protein alkB homolog 7;
DE   AltName: Full=Spermatogenesis cell proliferation-related protein;
DE   AltName: Full=Spermatogenesis-associated protein 11;
DE   Flags: Precursor;
GN   Name=ALKBH7; Synonyms=ABH7, SPATA11; ORFNames=UNQ6002/PRO34564;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0010883; P:regulation of lipid storage; ISS:UniProtKB.
DR   GO; GO:1902445; P:regulation of mitochondrial membrane permeability involved in programmed necrotic cell death; IMP:UniProtKB.
//
ID   ALKB8_HUMAN             Reviewed;         664 AA.
AC   Q96BT7; B1Q2M0; B4DEF6; Q8N989;
DE   RecName: Full=Alkylated DNA repair protein alkB homolog 8;
DE            EC=1.14.11.-;
DE   AltName: Full=Probable alpha-ketoglutarate-dependent dioxygenase ABH8;
DE   AltName: Full=S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8;
DE   AltName: Full=tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8;
DE            EC=2.1.1.229;
GN   Name=ALKBH8; Synonyms=ABH8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016300; F:tRNA (uracil) methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0030488; P:tRNA methylation; IDA:UniProtKB.
//
ID   ALKMO_HUMAN             Reviewed;         445 AA.
AC   Q6ZNB7; A4D114; A6NCH5;
DE   RecName: Full=Alkylglycerol monooxygenase;
DE            EC=1.14.16.5;
DE   AltName: Full=Transmembrane protein 195;
GN   Name=AGMO; Synonyms=TMEM195;
DR   GO; GO:0050479; F:glyceryl-ether monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IMP:UniProtKB.
DR   GO; GO:0046485; P:ether lipid metabolic process; IDA:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0006643; P:membrane lipid metabolic process; IDA:UniProtKB.
//
ID   ALK_HUMAN               Reviewed;        1620 AA.
AC   Q9UM73; Q4ZFX9; Q53QQ6; Q53RZ4; Q59FI3; Q9Y4K6;
DE   RecName: Full=ALK tyrosine kinase receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=Anaplastic lymphoma kinase;
DE   AltName: CD_antigen=CD246;
DE   Flags: Precursor;
GN   Name=ALK;
DR   GuidetoPHARMACOLOGY; 1839; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004704; F:NF-kappaB-inducing kinase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:MGI.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0048666; P:neuron development; TAS:UniProtKB.
DR   GO; GO:0038061; P:NIK/NF-kappaB signaling; TAS:GOC.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
//
ID   ALLC_HUMAN              Reviewed;         410 AA.
AC   Q8N6M5; Q53T95; Q5RL81; Q96RE6; Q9NZA7;
DE   RecName: Full=Probable allantoicase;
DE            EC=3.5.3.4;
DE   AltName: Full=Allantoate amidinohydrolase;
GN   Name=ALLC;
DR   GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:InterPro.
//
ID   ALM1L_HUMAN             Reviewed;         210 AA.
AC   Q96L16;
DE   RecName: Full=Putative ALMS1-like protein;
GN   Name=ALMS1P; Synonyms=ALMS1L;
//
ID   ALMS1_HUMAN             Reviewed;        4167 AA.
AC   Q8TCU4; Q53S05; Q580Q8; Q86VP9; Q9Y4G4;
DE   RecName: Full=Alstrom syndrome protein 1;
GN   Name=ALMS1; Synonyms=KIAA0328;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016197; P:endosomal transport; IMP:MGI.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; IMP:MGI.
//
ID   ALPK1_HUMAN             Reviewed;        1244 AA.
AC   Q96QP1; B4E3G1; F5H138; Q68CI9; Q6P9F9; Q6ZNK4; Q9P201;
DE   RecName: Full=Alpha-protein kinase 1;
DE            EC=2.7.11.-;
DE   AltName: Full=Chromosome 4 kinase;
DE   AltName: Full=Lymphocyte alpha-protein kinase;
GN   Name=ALPK1; Synonyms=KIAA1527, LAK;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ALPK2_HUMAN             Reviewed;        2170 AA.
AC   Q86TB3; Q6ZUX0; Q8NAT5; Q96L95;
DE   RecName: Full=Alpha-protein kinase 2;
DE            EC=2.7.11.-;
DE   AltName: Full=Heart alpha-protein kinase;
GN   Name=ALPK2; Synonyms=HAK;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ALPK3_HUMAN             Reviewed;        1907 AA.
AC   Q96L96; Q9P2L6;
DE   RecName: Full=Alpha-protein kinase 3;
DE            EC=2.7.11.-;
DE   AltName: Full=Muscle alpha-protein kinase;
GN   Name=ALPK3; Synonyms=KIAA1330, MAK;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007507; P:heart development; ISS:HGNC.
//
ID   ALR_HUMAN               Reviewed;         205 AA.
AC   P55789; Q53YM6; Q8TAH6; Q9H290; Q9UK40;
DE   RecName: Full=FAD-linked sulfhydryl oxidase ALR;
DE            EC=1.8.3.2;
DE   AltName: Full=Augmenter of liver regeneration;
DE            Short=hERV1;
DE   AltName: Full=Hepatopoietin;
GN   Name=GFER; Synonyms=ALR, HERV1, HPO;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0016972; F:thiol oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   ALS2_HUMAN              Reviewed;        1657 AA.
AC   Q96Q42; Q53TT1; Q53TV2; Q8N1E0; Q96PC4; Q96Q41; Q9H973; Q9HCK9;
DE   RecName: Full=Alsin;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 protein;
GN   Name=ALS2; Synonyms=ALS2CR6, KIAA1563;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; IEA:Ensembl.
DR   GO; GO:0007032; P:endosome organization; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:GOC.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:UniProtKB.
DR   GO; GO:0035022; P:positive regulation of Rac protein signal transduction; IC:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0001881; P:receptor recycling; IEA:Ensembl.
DR   GO; GO:0051036; P:regulation of endosome size; IEP:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0032316; P:regulation of Ran GTPase activity; NAS:GOC.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0016050; P:vesicle organization; IEA:Ensembl.
//
ID   ALS_HUMAN               Reviewed;         605 AA.
AC   P35858; B4DZY8; E9PGU3;
DE   RecName: Full=Insulin-like growth factor-binding protein complex acid labile subunit;
DE            Short=ALS;
DE   Flags: Precursor;
GN   Name=IGFALS; Synonyms=ALS;
DR   GO; GO:0005520; F:insulin-like growth factor binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ALX1_HUMAN              Reviewed;         326 AA.
AC   Q15699; Q546C8; Q96FH4;
DE   RecName: Full=ALX homeobox protein 1;
DE   AltName: Full=Cartilage homeoprotein 1;
DE            Short=CART-1;
GN   Name=ALX1; Synonyms=CART1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0001502; P:cartilage condensation; TAS:ProtInc.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0014031; P:mesenchymal cell development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ALX3_HUMAN              Reviewed;         343 AA.
AC   O95076; O95075; Q5T8M4;
DE   RecName: Full=Homeobox protein aristaless-like 3;
DE   AltName: Full=Proline-rich transcription factor ALX3;
GN   Name=ALX3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ALX4_HUMAN              Reviewed;         411 AA.
AC   Q9H161; Q96JN7; Q9H198; Q9HAY9;
DE   RecName: Full=Homeobox protein aristaless-like 4;
GN   Name=ALX4; Synonyms=KIAA1788;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IMP:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AMACR_HUMAN             Reviewed;         382 AA.
AC   Q9UHK6; A5YM47; B8Y916; B8Y918; F8W9N1; O43673; Q3KT79; Q96GH1;
AC   Q9Y3Q1;
DE   RecName: Full=Alpha-methylacyl-CoA racemase;
DE            EC=5.1.99.4;
DE   AltName: Full=2-methylacyl-CoA racemase;
GN   Name=AMACR;
DR   GO; GO:0008111; F:alpha-methylacyl-CoA racemase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AMBN_HUMAN              Reviewed;         447 AA.
AC   Q9NP70; Q3B862; Q9H2X1; Q9H4L1;
DE   RecName: Full=Ameloblastin;
DE   Flags: Precursor;
GN   Name=AMBN;
DR   GO; GO:0008083; F:growth factor activity; ISS:BHF-UCL.
DR   GO; GO:0030345; F:structural constituent of tooth enamel; IEA:InterPro.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:InterPro.
//
ID   AMBP_HUMAN              Reviewed;         352 AA.
AC   P02760; P00977; P02759; P78491; Q2TU33; Q5TBD7; Q9UC58; Q9UDI8;
DE   RecName: Full=Protein AMBP;
DE   Contains:
DE     RecName: Full=Alpha-1-microglobulin;
DE              Short=Protein HC;
DE     AltName: Full=Alpha-1 microglycoprotein;
DE     AltName: Full=Complex-forming glycoprotein heterogeneous in charge;
DE   Contains:
DE     RecName: Full=Inter-alpha-trypsin inhibitor light chain;
DE              Short=ITI-LC;
DE     AltName: Full=Bikunin;
DE     AltName: Full=EDC1;
DE     AltName: Full=HI-30;
DE     AltName: Full=Uronic-acid-rich protein;
DE   Contains:
DE     RecName: Full=Trypstatin;
DE   Flags: Precursor;
GN   Name=AMBP; Synonyms=HCP, ITIL;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0046904; F:calcium oxalate binding; NAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0019862; F:IgA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; NAS:UniProtKB.
DR   GO; GO:0042167; P:heme catabolic process; NAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0050777; P:negative regulation of immune response; NAS:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; TAS:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   AMD_HUMAN               Reviewed;         973 AA.
AC   P19021; A6NMR0; A8K293; O43211; O95080; Q16252; Q16253; Q54A45;
AC   Q86U53; Q8WVC7; Q9UCG0;
DE   RecName: Full=Peptidyl-glycine alpha-amidating monooxygenase;
DE            Short=PAM;
DE   Includes:
DE     RecName: Full=Peptidylglycine alpha-hydroxylating monooxygenase;
DE              Short=PHM;
DE              EC=1.14.17.3;
DE   Includes:
DE     RecName: Full=Peptidyl-alpha-hydroxyglycine alpha-amidating lyase;
DE              EC=4.3.2.5;
DE     AltName: Full=Peptidylamidoglycolate lyase;
DE              Short=PAL;
DE   Flags: Precursor;
GN   Name=PAM;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0004598; F:peptidylamidoglycolate lyase activity; IDA:UniProt.
DR   GO; GO:0004504; F:peptidylglycine monooxygenase activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProt.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0060173; P:limb development; IEA:Ensembl.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0022602; P:ovulation cycle process; IEA:Ensembl.
DR   GO; GO:0001519; P:peptide amidation; IDA:UniProt.
DR   GO; GO:0018032; P:protein amidation; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0050708; P:regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0009404; P:toxin metabolic process; IEA:Ensembl.
//
ID   AMELY_HUMAN             Reviewed;         206 AA.
AC   Q99218; Q6RWT1;
DE   RecName: Full=Amelogenin, Y isoform;
DE   Flags: Precursor;
GN   Name=AMELY; Synonyms=AMGL, AMGY;
DR   GO; GO:0030345; F:structural constituent of tooth enamel; IDA:BHF-UCL.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
//
ID   AMELX_HUMAN             Reviewed;         191 AA.
AC   Q99217; Q96NW6; Q9UCA7;
DE   RecName: Full=Amelogenin, X isoform;
DE   Flags: Precursor;
GN   Name=AMELX; Synonyms=AMG, AMGX;
DR   GO; GO:0008083; F:growth factor activity; ISS:BHF-UCL.
DR   GO; GO:0046848; F:hydroxyapatite binding; ISS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0030345; F:structural constituent of tooth enamel; IDA:BHF-UCL.
DR   GO; GO:0031214; P:biomineral tissue development; TAS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0070166; P:enamel mineralization; IMP:BHF-UCL.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0050801; P:ion homeostasis; TAS:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0070172; P:positive regulation of tooth mineralization; TAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:BHF-UCL.
DR   GO; GO:0034505; P:tooth mineralization; IMP:BHF-UCL.
//
ID   AMER1_HUMAN             Reviewed;        1135 AA.
AC   Q5JTC6; A2IB86; Q8N885;
DE   RecName: Full=APC membrane recruitment protein 1;
DE            Short=Amer1;
DE   AltName: Full=Protein FAM123B;
DE   AltName: Full=Wilms tumor gene on the X chromosome protein;
GN   Name=AMER1; Synonyms=FAM123B, WTX;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0072161; P:mesenchymal cell differentiation involved in kidney development; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AMER2_HUMAN             Reviewed;         671 AA.
AC   Q8N7J2; Q5RL80; Q5VX56; Q8N593; Q96NN5;
DE   RecName: Full=APC membrane recruitment protein 2;
DE            Short=Amer2;
DE   AltName: Full=Protein FAM123A;
GN   Name=AMER2; Synonyms=FAM123A;
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007398; P:ectoderm development; ISS:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AMER3_HUMAN             Reviewed;         861 AA.
AC   Q8N944; B7ZLH6;
DE   RecName: Full=APC membrane recruitment protein 3;
DE            Short=Amer3;
DE   AltName: Full=Protein FAM123C;
GN   Name=AMER3; Synonyms=FAM123C;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AMERL_HUMAN             Reviewed;         310 AA.
AC   Q6DCA0; B4E276;
DE   RecName: Full=AMMECR1-like protein;
GN   Name=AMMECR1L;
//
ID   AMFR_HUMAN              Reviewed;         643 AA.
AC   Q9UKV5; P26442; Q8IZ70;
DE   RecName: Full=E3 ubiquitin-protein ligase AMFR;
DE            EC=6.3.2.-;
DE   AltName: Full=Autocrine motility factor receptor;
DE            Short=AMF receptor;
DE   AltName: Full=RING finger protein 45;
DE   AltName: Full=gp78;
GN   Name=AMFR; Synonyms=RNF45;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   AMGO1_HUMAN             Reviewed;         493 AA.
AC   Q86WK6; B4DIM3; Q8IW71; Q9ULQ7;
DE   RecName: Full=Amphoterin-induced protein 1;
DE   AltName: Full=AMIGO-1;
DE   AltName: Full=Alivin-2;
DE   Flags: Precursor;
GN   Name=AMIGO1; Synonyms=ALI2, AMIGO, KIAA1163;
DR   GO; GO:0007413; P:axonal fasciculation; ISS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.
DR   GO; GO:0042552; P:myelination; ISS:UniProtKB.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; ISS:UniProtKB.
//
ID   AMGO2_HUMAN             Reviewed;         522 AA.
AC   Q86SJ2; Q4VBP6; Q7Z4A0; Q96CN8;
DE   RecName: Full=Amphoterin-induced protein 2;
DE   AltName: Full=AMIGO-2;
DE   AltName: Full=Alivin-1;
DE   AltName: Full=Differentially expressed in gastric adenocarcinomas;
DE            Short=DEGA;
DE   Flags: Precursor;
GN   Name=AMIGO2; Synonyms=ALI1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; ISS:UniProtKB.
//
ID   AMGO3_HUMAN             Reviewed;         504 AA.
AC   Q86WK7; Q494V6; Q96JH6;
DE   RecName: Full=Amphoterin-induced protein 3;
DE   AltName: Full=AMIGO-3;
DE   AltName: Full=Alivin-3;
DE   Flags: Precursor;
GN   Name=AMIGO3; Synonyms=ALI3, KIAA1851; ORFNames=UNQ6084/PRO20089;
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
//
ID   AMHR2_HUMAN             Reviewed;         573 AA.
AC   Q16671; A0AVE1; B9EGB7; E9PGD2; F8W1D2; Q13762; Q647K2;
DE   RecName: Full=Anti-Muellerian hormone type-2 receptor;
DE            EC=2.7.11.30;
DE   AltName: Full=Anti-Muellerian hormone type II receptor;
DE            Short=AMH type II receptor;
DE   AltName: Full=MIS type II receptor;
DE            Short=MISRII;
DE            Short=MRII;
DE   Flags: Precursor;
GN   Name=AMHR2; Synonyms=AMHR, MISR2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042562; F:hormone binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IMP:UniProtKB.
DR   GO; GO:0005026; F:transforming growth factor beta receptor activity, type II; IEA:Ensembl.
DR   GO; GO:0001880; P:Mullerian duct regression; NAS:UniProtKB.
DR   GO; GO:0007548; P:sex differentiation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   AMN1_HUMAN              Reviewed;         258 AA.
AC   Q8IY45; B7Z7J3; Q6NVU4; Q86X98;
DE   RecName: Full=Protein AMN1 homolog;
GN   Name=AMN1;
//
ID   AMMR1_HUMAN             Reviewed;         333 AA.
AC   Q9Y4X0; Q5JYV9; Q6P9D8; Q8WX22; Q9UIQ8;
DE   RecName: Full=AMME syndrome candidate gene 1 protein;
GN   Name=AMMECR1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   AMNLS_HUMAN             Reviewed;         453 AA.
AC   Q9BXJ7; Q6UX83;
DE   RecName: Full=Protein amnionless;
DE   Flags: Precursor;
GN   Name=AMN; ORFNames=UNQ513/PRO1028;
DR   GO; GO:0005102; F:receptor binding; IPI:UniProt.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0015889; P:cobalamin transport; IDA:UniProt.
DR   GO; GO:0007588; P:excretion; IEA:Ensembl.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProt.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:UniProt.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   AMOL1_HUMAN             Reviewed;         956 AA.
AC   Q8IY63; Q63HK7; Q8NDN0; Q8TEN8; Q8WXD1; Q96CM5;
DE   RecName: Full=Angiomotin-like protein 1;
GN   Name=AMOTL1;
DR   GO; GO:0042802; F:identical protein binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003365; P:establishment of cell polarity involved in ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AMOL2_HUMAN             Reviewed;         779 AA.
AC   Q9Y2J4; A8K6F1; B7Z5Q1; E9PHW3; Q53EP1; Q96F99; Q9UKB4;
DE   RecName: Full=Angiomotin-like protein 2;
DE   AltName: Full=Leman coiled-coil protein;
DE            Short=LCCP;
GN   Name=AMOTL2; Synonyms=KIAA0989;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   AMOT_HUMAN              Reviewed;        1084 AA.
AC   Q4VCS5; Q504X5; Q9HD27; Q9UPT1;
DE   RecName: Full=Angiomotin;
GN   Name=AMOT; Synonyms=KIAA1071;
DR   GO; GO:0043532; F:angiostatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IDA:MGI.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IDA:MGI.
DR   GO; GO:0006935; P:chemotaxis; IEA:Ensembl.
DR   GO; GO:0003365; P:establishment of cell polarity involved in ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; IGI:MGI.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:MGI.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0045793; P:positive regulation of cell size; TAS:UniProtKB.
DR   GO; GO:0040019; P:positive regulation of embryonic development; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:MGI.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   AMPB_HUMAN              Reviewed;         650 AA.
AC   Q9H4A4; Q9BVM9; Q9H1D4; Q9NPT7;
DE   RecName: Full=Aminopeptidase B;
DE            Short=AP-B;
DE            EC=3.4.11.6;
DE   AltName: Full=Arginine aminopeptidase;
DE   AltName: Full=Arginyl aminopeptidase;
GN   Name=RNPEP; Synonyms=APB;
DR   GO; GO:0004177; F:aminopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0004301; F:epoxide hydrolase activity; NAS:UniProtKB.
DR   GO; GO:0008235; F:metalloexopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IC:UniProtKB.
//
ID   AMPD1_HUMAN             Reviewed;         780 AA.
AC   P23109; A8K5N4; B2RAM1; F2Z3B3; Q5TF00; Q5TF02;
DE   RecName: Full=AMP deaminase 1;
DE            EC=3.5.4.6;
DE   AltName: Full=AMP deaminase isoform M;
DE   AltName: Full=Myoadenylate deaminase;
GN   Name=AMPD1;
DR   GO; GO:0003876; F:AMP deaminase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AMPD2_HUMAN             Reviewed;         879 AA.
AC   Q01433; B4DK50; B4DZI5; E9PNG0; Q14856; Q14857; Q16686; Q16687;
AC   Q16688; Q16729; Q5T693; Q5T695; Q96IA1; Q9UDX8; Q9UDX9; Q9UMU4;
DE   RecName: Full=AMP deaminase 2;
DE            EC=3.5.4.6;
DE   AltName: Full=AMP deaminase isoform L;
GN   Name=AMPD2;
DR   GO; GO:0003876; F:AMP deaminase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097009; P:energy homeostasis; IGI:MGI.
DR   GO; GO:0006188; P:IMP biosynthetic process; IGI:MGI.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AMPD3_HUMAN             Reviewed;         767 AA.
AC   Q01432; A0AUX0; B7Z2S2; B7Z763; B7Z877;
DE   RecName: Full=AMP deaminase 3;
DE            EC=3.5.4.6;
DE   AltName: Full=AMP deaminase isoform E;
DE   AltName: Full=Erythrocyte AMP deaminase;
GN   Name=AMPD3;
DR   GO; GO:0003876; F:AMP deaminase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006196; P:AMP catabolic process; TAS:ProtInc.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AMPE_HUMAN              Reviewed;         957 AA.
AC   Q07075; Q504U2;
DE   RecName: Full=Glutamyl aminopeptidase;
DE            Short=EAP;
DE            EC=3.4.11.7;
DE   AltName: Full=Aminopeptidase A;
DE            Short=AP-A;
DE   AltName: Full=Differentiation antigen gp160;
DE   AltName: CD_antigen=CD249;
GN   Name=ENPEP;
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; EXP:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0002005; P:angiotensin catabolic process in blood; NAS:UniProtKB.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IDA:MGI.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032835; P:glomerulus development; ISS:UniProtKB.
DR   GO; GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IDA:UniProtKB.
//
ID   AMPH_HUMAN              Reviewed;         695 AA.
AC   P49418; A4D1X8; A4D1X9; O43538; Q75MJ8; Q75MK5; Q75MM3; Q8N4G0;
DE   RecName: Full=Amphiphysin;
GN   Name=AMPH; Synonyms=AMPH1;
DR   GO; GO:0005543; F:phospholipid binding; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:Ensembl.
//
ID   AMPL_HUMAN              Reviewed;         519 AA.
AC   P28838; B3KMQ3; Q6IAM6; Q6P0L6; Q9UQE3;
DE   RecName: Full=Cytosol aminopeptidase;
DE            EC=3.4.11.1;
DE   AltName: Full=Leucine aminopeptidase 3;
DE            Short=LAP-3;
DE   AltName: Full=Leucyl aminopeptidase;
DE   AltName: Full=Peptidase S;
DE   AltName: Full=Proline aminopeptidase;
DE            EC=3.4.11.5;
DE   AltName: Full=Prolyl aminopeptidase;
GN   Name=LAP3; Synonyms=LAPEP, PEPS;
DR   GO; GO:0004177; F:aminopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0008235; F:metalloexopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   AMPN_HUMAN              Reviewed;         967 AA.
AC   P15144; Q16728; Q6GT90; Q8IUK3; Q8IVH3; Q9UCE0;
DE   RecName: Full=Aminopeptidase N;
DE            Short=AP-N;
DE            Short=hAPN;
DE            EC=3.4.11.2;
DE   AltName: Full=Alanyl aminopeptidase;
DE   AltName: Full=Aminopeptidase M;
DE            Short=AP-M;
DE   AltName: Full=Microsomal aminopeptidase;
DE   AltName: Full=Myeloid plasma membrane glycoprotein CD13;
DE   AltName: Full=gp150;
DE   AltName: CD_antigen=CD13;
GN   Name=ANPEP; Synonyms=APN, CD13, PEPN;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   AMPO_HUMAN              Reviewed;         819 AA.
AC   Q8N6M6; Q5T9B1; Q5T9B3; Q5T9B4; Q8WUL6; Q96M23; Q96SS1;
DE   RecName: Full=Aminopeptidase O;
DE            Short=AP-O;
DE            EC=3.4.11.-;
GN   Name=AOPEP; Synonyms=C9orf3, ONPEP;
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   AMPQ_HUMAN              Reviewed;         990 AA.
AC   Q6Q4G3; A8K6J0; C9JGD2; Q32MR1; Q4G0I9; Q4G0V2; Q86XA3; Q8NBZ2;
DE   RecName: Full=Aminopeptidase Q;
DE            Short=AP-Q;
DE            EC=3.4.11.-;
DE   AltName: Full=CHL2 antigen;
DE   AltName: Full=Laeverin;
GN   Name=AQPEP; Synonyms=LVRN;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   AMRA1_HUMAN             Reviewed;        1298 AA.
AC   Q9C0C7; A6XN33; D3DQP8; G3V193; Q86XD6; Q9H8Z0; Q9NXE7;
DE   RecName: Full=Activating molecule in BECN1-regulated autophagy protein 1;
GN   Name=AMBRA1; Synonyms=KIAA1736;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
//
ID   AMRP_HUMAN              Reviewed;         357 AA.
AC   P30533; D3DVR9; Q2M310; Q53HQ3; Q53HS6;
DE   RecName: Full=Alpha-2-macroglobulin receptor-associated protein;
DE            Short=Alpha-2-MRAP;
DE   AltName: Full=Low density lipoprotein receptor-related protein-associated protein 1;
DE            Short=RAP;
DE   Flags: Precursor;
GN   Name=LRPAP1; Synonyms=A2MRAP;
DR   GO; GO:0004873; F:asialoglycoprotein receptor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048019; F:receptor antagonist activity; IDA:BHF-UCL.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0070326; F:very-low-density lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; IDA:GOC.
DR   GO; GO:1900222; P:negative regulation of beta-amyloid clearance; IGI:BHF-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0010916; P:negative regulation of very-low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   AMTN_HUMAN              Reviewed;         209 AA.
AC   Q6UX39; Q0P503; Q0P506;
DE   RecName: Full=Amelotin;
DE   Flags: Precursor;
GN   Name=AMTN; ORFNames=UNQ689/PRO1329;
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:HGNC.
//
ID   AMY1_HUMAN              Reviewed;         511 AA.
AC   P04745; A6NJS5; A8K8H6; Q13763; Q5T083;
DE   RecName: Full=Alpha-amylase 1;
DE            EC=3.2.1.1;
DE   AltName: Full=1,4-alpha-D-glucan glucanohydrolase 1;
DE   AltName: Full=Salivary alpha-amylase;
DE   Flags: Precursor;
GN   Name=AMY1A; Synonyms=AMY1;
GN   and
GN   Name=AMY1B; Synonyms=AMY1;
GN   and
GN   Name=AMY1C; Synonyms=AMY1;
DR   GO; GO:0004556; F:alpha-amylase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
//
ID   AMY2B_HUMAN             Reviewed;         511 AA.
AC   P19961; B3KXB7; D3DT76; Q9UBH3;
DE   RecName: Full=Alpha-amylase 2B;
DE            EC=3.2.1.1;
DE   AltName: Full=1,4-alpha-D-glucan glucanohydrolase 2B;
DE   AltName: Full=Carcinoid alpha-amylase;
DE   Flags: Precursor;
GN   Name=AMY2B;
DR   GO; GO:0004556; F:alpha-amylase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
//
ID   AMYP_HUMAN              Reviewed;         511 AA.
AC   P04746; Q9UBH3;
DE   RecName: Full=Pancreatic alpha-amylase;
DE            Short=PA;
DE            EC=3.2.1.1;
DE   AltName: Full=1,4-alpha-D-glucan glucanohydrolase;
DE   Flags: Precursor;
GN   Name=AMY2A;
DR   GO; GO:0004556; F:alpha-amylase activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0031404; F:chloride ion binding; IDA:UniProtKB.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044245; P:polysaccharide digestion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AMZ1_HUMAN              Reviewed;         498 AA.
AC   Q400G9; Q8TF51;
DE   RecName: Full=Archaemetzincin-1;
DE            EC=3.4.-.-;
DE   AltName: Full=Archeobacterial metalloproteinase-like protein 1;
GN   Name=AMZ1; Synonyms=KIAA1950;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   AMZ2_HUMAN              Reviewed;         360 AA.
AC   Q86W34; A6NLD9; B3KR44; Q5XKF1; Q9NZE2;
DE   RecName: Full=Archaemetzincin-2;
DE            EC=3.4.-.-;
DE   AltName: Full=Archeobacterial metalloproteinase-like protein 2;
GN   Name=AMZ2; ORFNames=BM-014;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   AN13B_HUMAN             Reviewed;         626 AA.
AC   Q86YJ7; Q8N7S9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 13B;
GN   Name=ANKRD13B;
//
ID   AN13A_HUMAN             Reviewed;         590 AA.
AC   Q8IZ07; O60736;
DE   RecName: Full=Ankyrin repeat domain-containing protein 13A;
DE   AltName: Full=Protein KE03;
GN   Name=ANKRD13A; Synonyms=ANKRD13;
//
ID   AN13C_HUMAN             Reviewed;         541 AA.
AC   Q8N6S4; B3KQ97; Q5VYH4; Q5VYH5; Q6PJE4; Q9H0N9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 13C;
GN   Name=ANKRD13C;
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0006621; P:protein retention in ER lumen; IMP:BHF-UCL.
DR   GO; GO:2000209; P:regulation of anoikis; IDA:BHF-UCL.
DR   GO; GO:0010869; P:regulation of receptor biosynthetic process; IDA:BHF-UCL.
//
ID   AN18A_HUMAN             Reviewed;         992 AA.
AC   Q8IVF6; A7MD11; A8MVU5; Q5SY86; Q7Z468;
DE   RecName: Full=Ankyrin repeat domain-containing protein 18A;
GN   Name=ANKRD18A; Synonyms=KIAA2015;
//
ID   AN13D_HUMAN             Reviewed;         518 AA.
AC   Q6ZTN6; D6RCN6; Q0VAK0; Q0VGC3; Q6ZVD0; Q86SU1;
DE   RecName: Full=Ankyrin repeat domain-containing protein 13D;
GN   Name=ANKRD13D;
//
ID   AN20B_HUMAN             Reviewed;         823 AA.
AC   Q5CZ79; A6NC18;
DE   RecName: Full=Ankyrin repeat domain-containing protein 20B;
DE   AltName: Full=Ankyrin repeat domain-containing protein 20A pseudogene;
GN   Name=ANKRD20A8P; Synonyms=ANKRD20B;
//
ID   AN18B_HUMAN             Reviewed;        1011 AA.
AC   A2A2Z9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 18B;
GN   Name=ANKRD18B;
//
ID   AN30A_HUMAN             Reviewed;        1397 AA.
AC   Q9BXX3; Q5W025;
DE   RecName: Full=Ankyrin repeat domain-containing protein 30A;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-1;
GN   Name=ANKRD30A;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   AN30B_HUMAN             Reviewed;        1392 AA.
AC   Q9BXX2; B4DGP1; F8WAG3; Q4G175;
DE   RecName: Full=Ankyrin repeat domain-containing protein 30B;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-1.1;
GN   Name=ANKRD30B;
//
ID   AN32A_HUMAN             Reviewed;         249 AA.
AC   P39687; B2R6T4; Q53FK4; Q5J8L8; Q7M4N6;
DE   RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member A;
DE   AltName: Full=Acidic nuclear phosphoprotein pp32;
DE            Short=pp32;
DE   AltName: Full=Leucine-rich acidic nuclear protein;
DE            Short=LANP;
DE   AltName: Full=Mapmodulin;
DE   AltName: Full=Potent heat-stable protein phosphatase 2A inhibitor I1PP2A;
DE   AltName: Full=Putative HLA-DR-associated protein I;
DE            Short=PHAPI;
GN   Name=ANP32A; Synonyms=C15orf1, LANP, MAPM, PHAP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AN32B_HUMAN             Reviewed;         251 AA.
AC   Q92688; B2R9C7; O00655; P78458; P78459;
DE   RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member B;
DE   AltName: Full=Acidic protein rich in leucines;
DE   AltName: Full=Putative HLA-DR-associated protein I-2;
DE            Short=PHAPI2;
DE   AltName: Full=Silver-stainable protein SSP29;
GN   Name=ANP32B; Synonyms=APRIL, PHAPI2;
DR   GO; GO:0042393; F:histone binding; IDA:UniProt.
DR   GO; GO:0070063; F:RNA polymerase binding; IDA:UniProt.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProt.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProt.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IMP:UniProt.
//
ID   AN32C_HUMAN             Reviewed;         234 AA.
AC   O43423; Q4W5F9;
DE   RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member C;
DE   AltName: Full=Phosphoprotein 32-related protein 1;
DE   AltName: Full=Tumorigenic protein pp32r1;
GN   Name=ANP32C; Synonyms=PP32R1;
//
ID   AN32D_HUMAN             Reviewed;         131 AA.
AC   O95626; Q6NTC4;
DE   RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member D;
DE   AltName: Full=Phosphoprotein 32-related protein 2;
DE   AltName: Full=Tumorigenic protein pp32r2;
GN   Name=ANP32D; Synonyms=PP32R2;
//
ID   AN32E_HUMAN             Reviewed;         268 AA.
AC   Q9BTT0; B4E0I6; E9PEA6; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9;
DE   RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E;
DE   AltName: Full=LANP-like protein;
DE            Short=LANP-L;
GN   Name=ANP32E;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0019212; F:phosphatase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0043486; P:histone exchange; IDA:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:GOC.
//
ID   AN33B_HUMAN             Reviewed;         494 AA.
AC   A6NCL7;
DE   RecName: Full=Ankyrin repeat domain-containing protein 33B;
GN   Name=ANKRD33B;
//
ID   AN34A_HUMAN             Reviewed;         496 AA.
AC   Q69YU3; B3KSU3;
DE   RecName: Full=Ankyrin repeat domain-containing protein 34A;
GN   Name=ANKRD34A; Synonyms=ANKRD34;
//
ID   AN34B_HUMAN             Reviewed;         514 AA.
AC   A5PLL1; B2RPH1; Q68D79;
DE   RecName: Full=Ankyrin repeat domain-containing protein 34B;
GN   Name=ANKRD34B;
//
ID   AN36A_HUMAN             Reviewed;        1941 AA.
AC   A6QL64; B4E3I8; Q6UX02; Q86X62; Q9HCD1;
DE   RecName: Full=Ankyrin repeat domain-containing protein 36A;
GN   Name=ANKRD36; Synonyms=ANKRD36A, KIAA1641; ORFNames=UNQ2430/PRO499;
//
ID   AN36B_HUMAN             Reviewed;        1353 AA.
AC   Q8N2N9; Q08AK5; Q6IPR0; Q6PI49; Q8IZM7; Q8TDH6; Q96N30; Q9H759;
DE   RecName: Full=Ankyrin repeat domain-containing protein 36B;
DE   AltName: Full=CLL-associated antigen KW-1;
GN   Name=ANKRD36B;
//
ID   AN34C_HUMAN             Reviewed;         535 AA.
AC   P0C6C1; H3BNM1;
DE   RecName: Full=Ankyrin repeat domain-containing protein 34C;
GN   Name=ANKRD34C;
//
ID   ANAG_HUMAN              Reviewed;         743 AA.
AC   P54802;
DE   RecName: Full=Alpha-N-acetylglucosaminidase;
DE            EC=3.2.1.50;
DE   AltName: Full=N-acetyl-alpha-glucosaminidase;
DE            Short=NAG;
DE   Contains:
DE     RecName: Full=Alpha-N-acetylglucosaminidase 82 kDa form;
DE   Contains:
DE     RecName: Full=Alpha-N-acetylglucosaminidase 77 kDa form;
DE   Flags: Precursor;
GN   Name=NAGLU; Synonyms=UFHSD1;
DR   GO; GO:0004561; F:alpha-N-acetylglucosaminidase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0060119; P:inner ear receptor cell development; IEA:Ensembl.
DR   GO; GO:0045475; P:locomotor rhythm; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0046548; P:retinal rod cell development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AN36C_HUMAN             Reviewed;        1778 AA.
AC   Q5JPF3; C9JZ08; Q15694; Q53S06; Q658V2;
DE   RecName: Full=Ankyrin repeat domain-containing protein 36C;
DE   AltName: Full=Protein immuno-reactive with anti-PTH polyclonal antibodies;
GN   Name=ANKRD36C;
DR   GO; GO:0008200; F:ion channel inhibitor activity; NAS:UniProtKB.
//
ID   ANC2_HUMAN              Reviewed;         822 AA.
AC   Q9UJX6; Q5VSG1; Q96DG5; Q96GG4; Q9P2E1;
DE   RecName: Full=Anaphase-promoting complex subunit 2;
DE            Short=APC2;
DE   AltName: Full=Cyclosome subunit 2;
GN   Name=ANAPC2; Synonyms=APC2, KIAA1406;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008054; P:cyclin catabolic process; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   ANDR_HUMAN              Reviewed;         919 AA.
AC   P10275; A2RUN2; B1AKD7; Q9UD95;
DE   RecName: Full=Androgen receptor;
DE   AltName: Full=Dihydrotestosterone receptor;
DE   AltName: Full=Nuclear receptor subfamily 3 group C member 4;
GN   Name=AR; Synonyms=DHTR, NR3C4;
DR   GuidetoPHARMACOLOGY; 628; -.
DR   GO; GO:0005497; F:androgen binding; NAS:UniProtKB.
DR   GO; GO:0004882; F:androgen receptor activity; IDA:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; NAS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045720; P:negative regulation of integrin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045726; P:positive regulation of integrin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030850; P:prostate gland development; NAS:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:MGI.
DR   GO; GO:0090003; P:regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0007548; P:sex differentiation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ANFB_HUMAN              Reviewed;         134 AA.
AC   P16860; B0ZBE9; Q6FGY0; Q9P2Q7;
DE   RecName: Full=Natriuretic peptides B;
DE   AltName: Full=Gamma-brain natriuretic peptide;
DE   Contains:
DE     RecName: Full=Brain natriuretic peptide 32;
DE              Short=BNP(1-32);
DE              Short=BNP-32;
DE   Contains:
DE     RecName: Full=BNP(1-30);
DE   Contains:
DE     RecName: Full=BNP(1-29);
DE   Contains:
DE     RecName: Full=BNP(1-28);
DE   Contains:
DE     RecName: Full=BNP(2-31);
DE   Contains:
DE     RecName: Full=BNP(3-32);
DE   Contains:
DE     RecName: Full=BNP(3-30);
DE   Contains:
DE     RecName: Full=BNP(3-29);
DE   Contains:
DE     RecName: Full=BNP(4-32);
DE   Contains:
DE     RecName: Full=BNP(4-31);
DE   Contains:
DE     RecName: Full=BNP(4-30);
DE   Contains:
DE     RecName: Full=BNP(4-29);
DE   Contains:
DE     RecName: Full=BNP(4-27);
DE   Contains:
DE     RecName: Full=BNP(5-32);
DE   Contains:
DE     RecName: Full=BNP(5-31);
DE   Contains:
DE     RecName: Full=BNP(5-29);
DE   Flags: Precursor;
GN   Name=NPPB;
DR   GO; GO:0008613; F:diuretic hormone activity; TAS:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; NAS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0007589; P:body fluid secretion; TAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; TAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; TAS:UniProtKB.
DR   GO; GO:0035810; P:positive regulation of urine volume; TAS:UniProtKB.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:UniProtKB-KW.
DR   GO; GO:0043114; P:regulation of vascular permeability; TAS:UniProtKB.
DR   GO; GO:0042312; P:regulation of vasodilation; NAS:UniProtKB.
//
ID   ANFC_HUMAN              Reviewed;         126 AA.
AC   P23582; Q4ZG41;
DE   RecName: Full=C-type natriuretic peptide;
DE   Contains:
DE     RecName: Full=CNP-22;
DE   Contains:
DE     RecName: Full=CNP-29;
DE   Contains:
DE     RecName: Full=CNP-53;
DE   Flags: Precursor;
GN   Name=NPPC; Synonyms=CNP2;
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0003418; P:growth plate cartilage chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0003419; P:growth plate cartilage chondrocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051053; P:negative regulation of DNA metabolic process; IEA:Ensembl.
DR   GO; GO:0051447; P:negative regulation of meiotic cell cycle; IDA:MGI.
DR   GO; GO:1900194; P:negative regulation of oocyte maturation; IDA:MGI.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:UniProtKB-KW.
DR   GO; GO:0030814; P:regulation of cAMP metabolic process; IDA:MGI.
DR   GO; GO:0030823; P:regulation of cGMP metabolic process; IDA:MGI.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048660; P:regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   ANFY1_HUMAN             Reviewed;        1169 AA.
AC   Q9P2R3; A8KA65; Q5RKV4; Q9ULG5;
DE   RecName: Full=Ankyrin repeat and FYVE domain-containing protein 1;
DE   AltName: Full=Ankyrin repeats hooked to a zinc finger motif;
GN   Name=ANKFY1; Synonyms=ANKHZN, KIAA1255;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANF_HUMAN               Reviewed;         153 AA.
AC   P01160; Q13766; Q5JZE1;
DE   RecName: Full=Natriuretic peptides A;
DE   AltName: Full=CDD-ANF;
DE   AltName: Full=Prepronatriodilatin;
DE   Contains:
DE     RecName: Full=Cardiodilatin-related peptide;
DE              Short=CDP;
DE   Contains:
DE     RecName: Full=Atrial natriuretic factor;
DE              Short=ANF;
DE     AltName: Full=Atrial natriuretic peptide;
DE              Short=ANP;
DE   Flags: Precursor;
GN   Name=NPPA; Synonyms=ANP, PND;
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0003085; P:negative regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; IDA:UniProtKB.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:UniProtKB-KW.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   ANGE1_HUMAN             Reviewed;         670 AA.
AC   Q9UNK9; B4DWL7; O94859; Q8NCS9;
DE   RecName: Full=Protein angel homolog 1;
GN   Name=ANGEL1; Synonyms=KIAA0759;
//
ID   ANGE2_HUMAN             Reviewed;         544 AA.
AC   Q5VTE6; B7Z2U4; D3DTA3; Q86X13; Q8NHH3;
DE   RecName: Full=Protein angel homolog 2;
GN   Name=ANGEL2; Synonyms=KIAA0759L;
//
ID   ANGI_HUMAN              Reviewed;         147 AA.
AC   P03950; Q05CV1; Q53X86; Q6P5T2; Q8WXE7;
DE   RecName: Full=Angiogenin;
DE            EC=3.1.27.-;
DE   AltName: Full=Ribonuclease 5;
DE            Short=RNase 5;
DE   Flags: Precursor;
GN   Name=ANG; Synonyms=RNASE5;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IC:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; TAS:UniProtKB.
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0004540; F:ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; TAS:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0032431; P:activation of phospholipase A2 activity; IMP:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IMP:UniProtKB.
DR   GO; GO:0007154; P:cell communication; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0006651; P:diacylglycerol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0001556; P:oocyte maturation; NAS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; NAS:UniProtKB.
DR   GO; GO:0001890; P:placenta development; NAS:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0009303; P:rRNA transcription; IMP:UniProtKB.
//
ID   ANGL1_HUMAN             Reviewed;         491 AA.
AC   O95841; Q5T5Z5;
DE   RecName: Full=Angiopoietin-related protein 1;
DE   AltName: Full=Angiopoietin-3;
DE            Short=ANG-3;
DE   AltName: Full=Angiopoietin-like protein 1;
DE   Flags: Precursor;
GN   Name=ANGPTL1; Synonyms=ANG3, ANGPT3, ARP1;
GN   ORFNames=PSEC0154, UNQ162/PRO188;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   ANGL2_HUMAN             Reviewed;         493 AA.
AC   Q9UKU9; Q5JT58;
DE   RecName: Full=Angiopoietin-related protein 2;
DE   AltName: Full=Angiopoietin-like protein 2;
DE   Flags: Precursor;
GN   Name=ANGPTL2; Synonyms=ARP2; ORFNames=UNQ170/PRO196;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   ANGL4_HUMAN             Reviewed;         406 AA.
AC   Q9BY76; A8MY84; D6W670; Q53HQ6; Q53HU1; Q6UXN0; Q9HBV4; Q9NZU4;
AC   Q9Y5B3;
DE   RecName: Full=Angiopoietin-related protein 4;
DE   AltName: Full=Angiopoietin-like protein 4;
DE   AltName: Full=Hepatic fibrinogen/angiopoietin-related protein;
DE            Short=HFARP;
DE   Flags: Precursor;
GN   Name=ANGPTL4; Synonyms=ARP4, HFARP, PGAR;
GN   ORFNames=PP1158, PSEC0166, UNQ171/PRO197;
DR   GO; GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0051005; P:negative regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; TAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; ISS:BHF-UCL.
//
ID   ANGL3_HUMAN             Reviewed;         460 AA.
AC   Q9Y5C1;
DE   RecName: Full=Angiopoietin-related protein 3;
DE   AltName: Full=Angiopoietin-5;
DE            Short=ANG-5;
DE   AltName: Full=Angiopoietin-like protein 3;
DE   Flags: Precursor;
GN   Name=ANGPTL3; Synonyms=ANGPT5; ORFNames=UNQ153/PRO179;
DR   GO; GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0004859; F:phospholipase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0055090; P:acylglycerol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IPI:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006071; P:glycerol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0055088; P:lipid homeostasis; IDA:BHF-UCL.
DR   GO; GO:0019915; P:lipid storage; IDA:BHF-UCL.
DR   GO; GO:0051005; P:negative regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0010519; P:negative regulation of phospholipase activity; IDA:BHF-UCL.
DR   GO; GO:0009395; P:phospholipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0050996; P:positive regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; ISS:BHF-UCL.
//
ID   ANGL5_HUMAN             Reviewed;         388 AA.
AC   Q86XS5; A8K658; Q86VR9;
DE   RecName: Full=Angiopoietin-related protein 5;
DE   AltName: Full=Angiopoietin-like protein 5;
DE   Flags: Precursor;
GN   Name=ANGPTL5; ORFNames=UNQ5795/PRO19600;
//
ID   ANGL6_HUMAN             Reviewed;         470 AA.
AC   Q8NI99; A5PKV7; Q9BZZ0;
DE   RecName: Full=Angiopoietin-related protein 6;
DE   AltName: Full=Angiopoietin-like protein 6;
DE   AltName: Full=Angiopoietin-related growth factor;
DE   AltName: Full=Angiopoietin-related protein 5;
DE   Flags: Precursor;
GN   Name=ANGPTL6; Synonyms=AGF, ARP5; ORFNames=UNQ152/PRO178;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   ANGL7_HUMAN             Reviewed;         346 AA.
AC   O43827; B2R9B2; Q4ZGK4;
DE   RecName: Full=Angiopoietin-related protein 7;
DE   AltName: Full=Angiopoietin-like factor;
DE   AltName: Full=Angiopoietin-like protein 7;
DE   AltName: Full=Cornea-derived transcript 6 protein;
DE   Flags: Precursor;
GN   Name=ANGPTL7; Synonyms=CDT6; ORFNames=UNQ313/PRO356;
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
//
ID   ANGP1_HUMAN             Reviewed;         498 AA.
AC   Q15389; Q5HYA0;
DE   RecName: Full=Angiopoietin-1;
DE            Short=ANG-1;
DE   Flags: Precursor;
GN   Name=ANGPT1; Synonyms=KIAA0003;
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0031589; P:cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0072012; P:glomerulus vasculature development; ISS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030210; P:heparin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0014842; P:regulation of satellite cell proliferation; IDA:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0048014; P:Tie signaling pathway; IDA:UniProtKB.
//
ID   ANGP2_HUMAN             Reviewed;         496 AA.
AC   O15123; A0AV38; A8K205; B7ZLM7; Q9NRR7; Q9P2Y7;
DE   RecName: Full=Angiopoietin-2;
DE            Short=ANG-2;
DE   Flags: Precursor;
GN   Name=ANGPT2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0072012; P:glomerulus vasculature development; ISS:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0050928; P:negative regulation of positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048014; P:Tie signaling pathway; IDA:UniProtKB.
//
ID   ANGP4_HUMAN             Reviewed;         503 AA.
AC   Q9Y264; Q5TFF4; Q9H4Z4;
DE   RecName: Full=Angiopoietin-4;
DE            Short=ANG-4;
DE   AltName: Full=Angiopoietin-3;
DE            Short=ANG-3;
DE   Flags: Precursor;
GN   Name=ANGPT4; Synonyms=ANG3, ANG4;
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IDA:UniProtKB.
DR   GO; GO:0030297; F:transmembrane receptor protein tyrosine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
//
ID   ANGT_HUMAN              Reviewed;         485 AA.
AC   P01019; Q16358; Q16359; Q96F91;
DE   RecName: Full=Angiotensinogen;
DE   AltName: Full=Serpin A8;
DE   Contains:
DE     RecName: Full=Angiotensin-1;
DE     AltName: Full=Angiotensin 1-10;
DE     AltName: Full=Angiotensin I;
DE              Short=Ang I;
DE   Contains:
DE     RecName: Full=Angiotensin-2;
DE     AltName: Full=Angiotensin 1-8;
DE     AltName: Full=Angiotensin II;
DE              Short=Ang II;
DE   Contains:
DE     RecName: Full=Angiotensin-3;
DE     AltName: Full=Angiotensin 2-8;
DE     AltName: Full=Angiotensin III;
DE              Short=Ang III;
DE     AltName: Full=Des-Asp[1]-angiotensin II;
DE   Contains:
DE     RecName: Full=Angiotensin-4;
DE     AltName: Full=Angiotensin 3-8;
DE     AltName: Full=Angiotensin IV;
DE              Short=Ang IV;
DE   Contains:
DE     RecName: Full=Angiotensin 1-9;
DE   Contains:
DE     RecName: Full=Angiotensin 1-7;
DE   Contains:
DE     RecName: Full=Angiotensin 1-5;
DE   Contains:
DE     RecName: Full=Angiotensin 1-4;
DE   Flags: Precursor;
GN   Name=AGT; Synonyms=SERPINA8;
DR   GO; GO:0008083; F:growth factor activity; TAS:BHF-UCL.
DR   GO; GO:0005179; F:hormone activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0031702; F:type 1 angiotensin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031703; F:type 2 angiotensin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IEA:Ensembl.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0001998; P:angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0003051; P:angiotensin-mediated drinking behavior; IEA:Ensembl.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0048143; P:astrocyte activation; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; TAS:BHF-UCL.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0035411; P:catenin import into nucleus; IEA:Ensembl.
DR   GO; GO:0061049; P:cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006883; P:cellular sodium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0050663; P:cytokine secretion; IEA:Ensembl.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0008065; P:establishment of blood-nerve barrier; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0048144; P:fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; TAS:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; NAS:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0051387; P:negative regulation of neurotrophin TRK receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0034104; P:negative regulation of tissue remodeling; IEA:Ensembl.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:BHF-UCL.
DR   GO; GO:0001543; P:ovarian follicle rupture; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0010535; P:positive regulation of activation of JAK2 kinase activity; IMP:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IDA:UniProtKB.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0001819; P:positive regulation of cytokine production; TAS:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0003331; P:positive regulation of extracellular matrix constituent secretion; IEA:Ensembl.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0033864; P:positive regulation of NAD(P)H oxidase activity; TAS:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IMP:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; TAS:BHF-UCL.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0002034; P:regulation of blood vessel size by renin-angiotensin; TAS:BHF-UCL.
DR   GO; GO:0002016; P:regulation of blood volume by renin-angiotensin; NAS:BHF-UCL.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0014061; P:regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0002019; P:regulation of renal output by angiotensin; NAS:BHF-UCL.
DR   GO; GO:0035813; P:regulation of renal sodium excretion; NAS:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; NAS:BHF-UCL.
DR   GO; GO:0001999; P:renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0003014; P:renal system process; IDA:UniProt.
DR   GO; GO:0002018; P:renin-angiotensin regulation of aldosterone production; NAS:BHF-UCL.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0014873; P:response to muscle activity involved in regulation of muscle adaptation; ISS:BHF-UCL.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0048659; P:smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; IEA:Ensembl.
DR   GO; GO:0070471; P:uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   ANHX_HUMAN              Reviewed;         379 AA.
AC   E9PGG2; Q96MC1;
DE   RecName: Full=Anomalous homeobox protein;
GN   Name=ANHX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   ANK1_HUMAN              Reviewed;        1881 AA.
AC   P16157; A0PJN8; A6NJ23; E5RFL7; O43400; Q13768; Q53ER1; Q59FP2;
AC   Q8N604; Q99407;
DE   RecName: Full=Ankyrin-1;
DE            Short=ANK-1;
DE   AltName: Full=Ankyrin-R;
DE   AltName: Full=Erythrocyte ankyrin;
GN   Name=ANK1; Synonyms=ANK;
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; NAS:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:BHF-UCL.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; NAS:UniProtKB.
DR   GO; GO:0045199; P:maintenance of epithelial cell apical/basal polarity; TAS:UniProtKB.
DR   GO; GO:0015672; P:monovalent inorganic cation transport; IEA:Ensembl.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010638; P:positive regulation of organelle organization; IEA:Ensembl.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   ANK2_HUMAN              Reviewed;        3957 AA.
AC   Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5;
DE   RecName: Full=Ankyrin-2;
DE            Short=ANK-2;
DE   AltName: Full=Ankyrin-B;
DE   AltName: Full=Brain ankyrin;
DE   AltName: Full=Non-erythroid ankyrin;
GN   Name=ANK2;
DR   GO; GO:0051117; F:ATPase binding; ISS:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; ISS:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0030507; F:spectrin binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0086066; P:atrial cardiac muscle cell to AV node cell communication; ISS:BHF-UCL.
DR   GO; GO:0003283; P:atrial septum development; IMP:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0034613; P:cellular protein localization; IGI:BHF-UCL.
DR   GO; GO:0086046; P:membrane depolarization during SA node cell action potential; TAS:BHF-UCL.
DR   GO; GO:0030913; P:paranodal junction assembly; IEA:Ensembl.
DR   GO; GO:1901021; P:positive regulation of calcium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; ISS:BHF-UCL.
DR   GO; GO:2001259; P:positive regulation of cation channel activity; ISS:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IGI:BHF-UCL.
DR   GO; GO:1901018; P:positive regulation of potassium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; ISS:BHF-UCL.
DR   GO; GO:0034394; P:protein localization to cell surface; ISS:BHF-UCL.
DR   GO; GO:0070972; P:protein localization to endoplasmic reticulum; IGI:BHF-UCL.
DR   GO; GO:0036309; P:protein localization to M-band; ISS:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; IGI:BHF-UCL.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IGI:BHF-UCL.
DR   GO; GO:0036371; P:protein localization to T-tubule; ISS:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; ISS:BHF-UCL.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IEA:Ensembl.
DR   GO; GO:1901019; P:regulation of calcium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IGI:BHF-UCL.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IGI:BHF-UCL.
DR   GO; GO:0086036; P:regulation of cardiac muscle cell membrane potential; IEA:Ensembl.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0010882; P:regulation of cardiac muscle contraction by calcium ion signaling; IMP:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IGI:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0031647; P:regulation of protein stability; IC:BHF-UCL.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IGI:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0086015; P:SA node cell action potential; ISS:BHF-UCL.
DR   GO; GO:0086070; P:SA node cell to atrial cardiac muscle cell communication; IMP:BHF-UCL.
DR   GO; GO:0070296; P:sarcoplasmic reticulum calcium ion transport; TAS:BHF-UCL.
DR   GO; GO:0033292; P:T-tubule organization; ISS:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   ANK3_HUMAN              Reviewed;        4377 AA.
AC   Q12955; B1AQT2; B4DIL1; E9PE32; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4;
AC   Q9H0P5;
DE   RecName: Full=Ankyrin-3;
DE            Short=ANK-3;
DE   AltName: Full=Ankyrin-G;
GN   Name=ANK3;
DR   GO; GO:0045296; F:cadherin binding; ISS:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; ISS:BHF-UCL.
DR   GO; GO:0030507; F:spectrin binding; ISS:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IMP:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:ProtInc.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:BHF-UCL.
DR   GO; GO:0072660; P:maintenance of protein location in plasma membrane; IGI:BHF-UCL.
DR   GO; GO:0071709; P:membrane assembly; IMP:BHF-UCL.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:BHF-UCL.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; ISS:BHF-UCL.
DR   GO; GO:0007009; P:plasma membrane organization; IMP:BHF-UCL.
DR   GO; GO:0010650; P:positive regulation of cell communication by electrical coupling; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0034112; P:positive regulation of homotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:1900827; P:positive regulation of membrane depolarization during cardiac muscle cell action potential; ISS:BHF-UCL.
DR   GO; GO:0045838; P:positive regulation of membrane potential; ISS:BHF-UCL.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:2000651; P:positive regulation of sodium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0043266; P:regulation of potassium ion transport; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   ANKAR_HUMAN             Reviewed;        1434 AA.
AC   Q7Z5J8; Q3ZCS6; Q4G0M2; Q6ZU02;
DE   RecName: Full=Ankyrin and armadillo repeat-containing protein;
GN   Name=ANKAR;
//
ID   ANKE1_HUMAN             Reviewed;         776 AA.
AC   Q9NU02; B3KUQ0; Q9H6Y9;
DE   RecName: Full=Ankyrin repeat and EF-hand domain-containing protein 1;
DE   AltName: Full=Ankyrin repeat domain-containing protein 5;
GN   Name=ANKEF1; Synonyms=ANKRD5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   ANKH1_HUMAN             Reviewed;        2542 AA.
AC   Q8IWZ3; A6NH85; Q149P2; Q8IWZ2; Q8WY90; Q96G77; Q96GK0; Q9H2U0;
AC   Q9HA95; Q9NWG4; Q9UPR7;
DE   RecName: Full=Ankyrin repeat and KH domain-containing protein 1;
DE   AltName: Full=HIV-1 Vpr-binding ankyrin repeat protein;
DE   AltName: Full=Multiple ankyrin repeats single KH domain;
DE            Short=hMASK;
GN   Name=ANKHD1; Synonyms=KIAA1085, MASK, VBARP; ORFNames=PP2500;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANKF1_HUMAN             Reviewed;         763 AA.
AC   Q8N957;
DE   RecName: Full=Ankyrin repeat and fibronectin type-III domain-containing protein 1;
GN   Name=ANKFN1;
//
ID   ANKH_HUMAN              Reviewed;         492 AA.
AC   Q9HCJ1; B2RCA7; D3DTD4; Q9NQW2;
DE   RecName: Full=Progressive ankylosis protein homolog;
DE            Short=ANK;
GN   Name=ANKH; Synonyms=KIAA1581; ORFNames=UNQ241/PRO274;
DR   GO; GO:0030504; F:inorganic diphosphate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015114; F:phosphate ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030505; P:inorganic diphosphate transport; IDA:GOC.
DR   GO; GO:0007626; P:locomotory behavior; NAS:UniProtKB.
DR   GO; GO:0030500; P:regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; NAS:UniProtKB.
//
ID   ANKK1_HUMAN             Reviewed;         765 AA.
AC   Q8NFD2;
DE   RecName: Full=Ankyrin repeat and protein kinase domain-containing protein 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase PKK2;
DE   AltName: Full=Sugen kinase 288;
DE            Short=SgK288;
DE   AltName: Full=X-kinase;
GN   Name=ANKK1; Synonyms=PKK2, SGK288;
DR   GuidetoPHARMACOLOGY; 1932; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ANKL1_HUMAN             Reviewed;         615 AA.
AC   Q8NAG6; A8VU82; Q8N8J8;
DE   RecName: Full=Ankyrin repeat and LEM domain-containing protein 1;
DE   AltName: Full=Ankyrin repeat domain-containing protein 41;
DE   AltName: Full=LEM-domain containing protein 3;
GN   Name=ANKLE1; Synonyms=ANKRD41, LEM3;
//
ID   ANKL2_HUMAN             Reviewed;         938 AA.
AC   Q86XL3; A8KAG3; B3KN97; B3KSF8; O75176; Q6P6A5; Q8TAZ9; Q96DH4;
DE   RecName: Full=Ankyrin repeat and LEM domain-containing protein 2;
DE   AltName: Full=LEM domain-containing protein 4;
GN   Name=ANKLE2; Synonyms=KIAA0692, LEM4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; IMP:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:UniProtKB.
//
ID   ANKR1_HUMAN             Reviewed;         319 AA.
AC   Q15327; Q96LE7;
DE   RecName: Full=Ankyrin repeat domain-containing protein 1;
DE   AltName: Full=Cardiac ankyrin repeat protein;
DE   AltName: Full=Cytokine-inducible gene C-193 protein;
DE   AltName: Full=Cytokine-inducible nuclear protein;
GN   Name=ANKRD1; Synonyms=C193, CARP, HA1A2;
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:BHF-UCL.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0035994; P:response to muscle stretch; IMP:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; NAS:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ANKR2_HUMAN             Reviewed;         360 AA.
AC   Q9GZV1; Q3B778; Q5T456; Q70EZ9; Q8WUD7; Q96MG0; Q9NQC9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 2;
DE   AltName: Full=Skeletal muscle ankyrin repeat protein;
DE            Short=hArpp;
GN   Name=ANKRD2; Synonyms=ARPP;
DR   GO; GO:0043422; F:protein kinase B binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; NAS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; NAS:UniProtKB.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   ANKR6_HUMAN             Reviewed;         727 AA.
AC   Q9Y2G4; B3KUC3; Q5JUJ4; Q5JUJ5; Q8IUQ8; Q9NU24; Q9UFQ9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 6;
DE   AltName: Full=Diversin;
GN   Name=ANKRD6; Synonyms=KIAA0957;
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:2000096; P:positive regulation of Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   ANKR7_HUMAN             Reviewed;         254 AA.
AC   Q92527; B4DYF5; Q96QN1; Q9UDM3;
DE   RecName: Full=Ankyrin repeat domain-containing protein 7;
DE   AltName: Full=Testis-specific protein TSA806;
GN   Name=ANKRD7;
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
//
ID   ANKS3_HUMAN             Reviewed;         656 AA.
AC   Q6ZW76; B4DWU4; D3DUE2; Q8TF25;
DE   RecName: Full=Ankyrin repeat and SAM domain-containing protein 3;
GN   Name=ANKS3; Synonyms=KIAA1977;
//
ID   ANKR9_HUMAN             Reviewed;         317 AA.
AC   Q96BM1; A8K753;
DE   RecName: Full=Ankyrin repeat domain-containing protein 9;
GN   Name=ANKRD9;
//
ID   ANKS6_HUMAN             Reviewed;         871 AA.
AC   Q68DC2; A0SE62; Q5VSL0; Q5VSL2; Q5VSL3; Q5VSL4; Q68DB8; Q6P2R2;
AC   Q8N9L6; Q96D62;
DE   RecName: Full=Ankyrin repeat and SAM domain-containing protein 6;
DE   AltName: Full=Ankyrin repeat domain-containing protein 14;
DE   AltName: Full=SamCystin;
DE   AltName: Full=Sterile alpha motif domain-containing protein 6;
DE            Short=SAM domain-containing protein 6;
GN   Name=ANKS6; Synonyms=ANKRD14, PKDR1, SAMD6;
//
ID   ANKUB_HUMAN             Reviewed;         424 AA.
AC   A6NFN9;
DE   RecName: Full=Protein ANKUB1;
DE   AltName: Full=Ankyrin repeat and ubiquitin domain-containing 1;
GN   Name=ANKUB1; Synonyms=C3orf16;
//
ID   ANKY1_HUMAN             Reviewed;         941 AA.
AC   Q9P2S6; B2RB78; Q4ZFV3; Q8IYX5; Q8NDK5; Q9H0V8; Q9NX10;
DE   RecName: Full=Ankyrin repeat and MYND domain-containing protein 1;
DE   AltName: Full=Testis-specific ankyrin-like protein 1;
DE   AltName: Full=Zinc finger MYND domain-containing protein 13;
GN   Name=ANKMY1; Synonyms=TSAL1, ZMYND13;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ANKY2_HUMAN             Reviewed;         441 AA.
AC   Q8IV38; A4D124; Q659G1; Q96BL3;
DE   RecName: Full=Ankyrin repeat and MYND domain-containing protein 2;
GN   Name=ANKMY2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ANKZ1_HUMAN             Reviewed;         726 AA.
AC   Q9H8Y5; Q9NVZ4;
DE   RecName: Full=Ankyrin repeat and zinc finger domain-containing protein 1;
DE   AltName: Full=Zinc finger protein 744;
GN   Name=ANKZF1; Synonyms=ZNF744;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANLN_HUMAN              Reviewed;        1124 AA.
AC   Q9NQW6; Q5CZ78; Q6NSK5; Q9H8Y4; Q9NVN9; Q9NVP0;
DE   RecName: Full=Actin-binding protein anillin;
GN   Name=ANLN;
DR   GO; GO:0003779; F:actin binding; IDA:MGI.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000281; P:mitotic cytokinesis; IDA:MGI.
DR   GO; GO:0007096; P:regulation of exit from mitosis; TAS:ProtInc.
DR   GO; GO:0000921; P:septin ring assembly; TAS:ProtInc.
//
ID   ANM1_HUMAN              Reviewed;         361 AA.
AC   Q99873; B4E3C3; G5E9B6; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872;
AC   Q99874; Q9NZ04; Q9NZ05; Q9NZ06;
DE   RecName: Full=Protein arginine N-methyltransferase 1;
DE            EC=2.1.1.-;
DE   AltName: Full=Histone-arginine N-methyltransferase PRMT1;
DE            EC=2.1.1.125;
DE   AltName: Full=Interferon receptor 1-bound protein 4;
GN   Name=PRMT1; Synonyms=HMT2, HRMT1L2, IR1B4;
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044020; F:histone methyltransferase activity (H4-R3 specific); IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008168; F:methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008170; F:N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043985; P:histone H4-R3 methylation; IDA:UniProtKB.
DR   GO; GO:0016571; P:histone methylation; IDA:UniProtKB.
DR   GO; GO:0045653; P:negative regulation of megakaryocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IDA:UniProtKB.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IBA:RefGenome.
DR   GO; GO:0006479; P:protein methylation; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   ANM2_HUMAN              Reviewed;         433 AA.
AC   P55345; B7U630; B7U631; B7U632; P78350; Q498Y5; Q5U7D4; Q6FHF0;
AC   Q99781; Q9BW15; Q9UMC2;
DE   RecName: Full=Protein arginine N-methyltransferase 2;
DE            EC=2.1.1.-;
DE   AltName: Full=Histone-arginine N-methyltransferase PRMT2;
DE            EC=2.1.1.125;
GN   Name=PRMT2; Synonyms=HMT1, HRMT1L1;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:UniProtKB.
DR   GO; GO:0033142; F:progesterone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0048588; P:developmental cell growth; ISS:UniProtKB.
DR   GO; GO:0034969; P:histone arginine methylation; IBA:RefGenome.
DR   GO; GO:0016571; P:histone methylation; IDA:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IBA:RefGenome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IGI:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006479; P:protein methylation; TAS:ProtInc.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ANM3_HUMAN              Reviewed;         531 AA.
AC   O60678; B4DUC7;
DE   RecName: Full=Protein arginine N-methyltransferase 3;
DE            EC=2.1.1.-;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3;
GN   Name=PRMT3; Synonyms=HRMT1L3;
DR   GO; GO:0008469; F:histone-arginine N-methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0072341; F:modified amino acid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0034969; P:histone arginine methylation; IBA:RefGenome.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   ANM5_HUMAN              Reviewed;         637 AA.
AC   O14744; A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7;
AC   Q6IBR1; Q9UKH1;
DE   RecName: Full=Protein arginine N-methyltransferase 5;
DE            EC=2.1.1.-;
DE   AltName: Full=72 kDa ICln-binding protein;
DE   AltName: Full=Histone-arginine N-methyltransferase PRMT5;
DE            EC=2.1.1.125;
DE   AltName: Full=Jak-binding protein 1;
DE   AltName: Full=Shk1 kinase-binding protein 1 homolog;
DE            Short=SKB1 homolog;
DE            Short=SKB1Hs;
DE   Contains:
DE     RecName: Full=Protein arginine N-methyltransferase 5, N-terminally processed;
GN   Name=PRMT5; Synonyms=HRMT1L5, IBP72, JBP1, SKB1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0008469; F:histone-arginine N-methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035243; F:protein-arginine omega-N symmetric methyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0042118; P:endothelial cell activation; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043985; P:histone H4-R3 methylation; NAS:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IMP:UniProtKB.
DR   GO; GO:0019918; P:peptidyl-arginine methylation, to symmetrical-dimethyl arginine; IMP:GOC.
DR   GO; GO:0035246; P:peptidyl-arginine N-methylation; IDA:MGI.
DR   GO; GO:0006479; P:protein methylation; IEA:InterPro.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ANM6_HUMAN              Reviewed;         375 AA.
AC   Q96LA8; A3KME1; B4DID8; Q5T5Y5; Q6DKI4; Q9NVR8;
DE   RecName: Full=Protein arginine N-methyltransferase 6;
DE            EC=2.1.1.-;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6;
DE   AltName: Full=Histone-arginine N-methyltransferase PRMT6;
DE            EC=2.1.1.125;
GN   Name=PRMT6; Synonyms=HRMT1L6;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0070612; F:histone methyltransferase activity (H2A-R3 specific); IDA:UniProtKB.
DR   GO; GO:0070611; F:histone methyltransferase activity (H3-R2 specific); IDA:UniProtKB.
DR   GO; GO:0044020; F:histone methyltransferase activity (H4-R3 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:UniProtKB.
DR   GO; GO:0034970; P:histone H3-R2 methylation; IDA:UniProtKB.
DR   GO; GO:0043985; P:histone H4-R3 methylation; IDA:GOC.
DR   GO; GO:0016571; P:histone methylation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ANM7_HUMAN              Reviewed;         692 AA.
AC   Q9NVM4; B3KPR0; B3KUG9; B4E379; Q96PV5; Q9H9L0;
DE   RecName: Full=Protein arginine N-methyltransferase 7;
DE            EC=2.1.1.-;
DE   AltName: Full=Histone-arginine N-methyltransferase PRMT7;
DE            EC=2.1.1.125;
DE   AltName: Full=[Myelin basic protein]-arginine N-methyltransferase PRMT7;
DE            EC=2.1.1.126;
GN   Name=PRMT7; Synonyms=KIAA1933;
DR   GO; GO:0016277; F:[myelin basic protein]-arginine N-methyltransferase activity; IDA:HGNC.
DR   GO; GO:0042393; F:histone binding; IC:HGNC.
DR   GO; GO:0044020; F:histone methyltransferase activity (H4-R3 specific); ISS:UniProtKB.
DR   GO; GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:HGNC.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035243; F:protein-arginine omega-N symmetric methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IDA:HGNC.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0034969; P:histone arginine methylation; ISS:UniProtKB.
DR   GO; GO:0016571; P:histone methylation; IDA:HGNC.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IMP:UniProtKB.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IBA:RefGenome.
DR   GO; GO:0019918; P:peptidyl-arginine methylation, to symmetrical-dimethyl arginine; IDA:GOC.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; ISS:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; IC:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ANM8_HUMAN              Reviewed;         394 AA.
AC   Q9NR22; B2RDP0; Q8TBJ8;
DE   RecName: Full=Protein arginine N-methyltransferase 8;
DE            EC=2.1.1.-;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4;
GN   Name=PRMT8; Synonyms=HRMT1L3, HRMT1L4;
DR   GO; GO:0044020; F:histone methyltransferase activity (H4-R3 specific); IBA:RefGenome.
DR   GO; GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:HGNC.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:HGNC.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035241; F:protein-arginine omega-N monomethyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IDA:HGNC.
DR   GO; GO:0034969; P:histone arginine methylation; IDA:GOC.
DR   GO; GO:0043985; P:histone H4-R3 methylation; IBA:GOC.
DR   GO; GO:0016571; P:histone methylation; IDA:HGNC.
DR   GO; GO:0018216; P:peptidyl-arginine methylation; IDA:UniProtKB.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IDA:HGNC.
DR   GO; GO:0043393; P:regulation of protein binding; TAS:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   ANM9_HUMAN              Reviewed;         845 AA.
AC   Q6P2P2; A8KA39; B3KU92; Q6ZR58; Q8N383; Q9BT55; Q9NT98;
DE   RecName: Full=Putative protein arginine N-methyltransferase 9;
DE   AltName: Full=Putative protein arginine N-methyltransferase 10;
DE            EC=2.1.1.-;
GN   Name=PRMT9; Synonyms=PRMT10;
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
//
ID   ANO10_HUMAN             Reviewed;         660 AA.
AC   Q9NW15; A8K8K3; A8MV74; B3KTZ1; B3KY93; B4DJ83; B4DNK2; B7WP12;
AC   C9JHS1; Q8IXX9;
DE   RecName: Full=Anoctamin-10;
DE   AltName: Full=Transmembrane protein 16K;
GN   Name=ANO10; Synonyms=TMEM16K;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO1_HUMAN              Reviewed;         986 AA.
AC   Q5XXA6; A8KAM3; Q8IYY8; Q8N7V3;
DE   RecName: Full=Anoctamin-1;
DE   AltName: Full=Discovered on gastrointestinal stromal tumors protein 1;
DE   AltName: Full=Oral cancer overexpressed protein 2;
DE   AltName: Full=Transmembrane protein 16A;
DE   AltName: Full=Tumor-amplified and overexpressed sequence 2;
GN   Name=ANO1; Synonyms=DOG1, ORAOV2, TAOS2, TMEM16A;
DR   GuidetoPHARMACOLOGY; 708; -.
DR   GO; GO:0005229; F:intracellular calcium activated chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; ISS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO2_HUMAN              Reviewed;        1003 AA.
AC   Q9NQ90; C4N787; Q9H847;
DE   RecName: Full=Anoctamin-2;
DE   AltName: Full=Transmembrane protein 16B;
GN   Name=ANO2; Synonyms=C12orf3, TMEM16B;
DR   GO; GO:0005229; F:intracellular calcium activated chloride channel activity; IDA:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO3_HUMAN              Reviewed;         981 AA.
AC   Q9BYT9;
DE   RecName: Full=Anoctamin-3;
DE   AltName: Full=Transmembrane protein 16C;
GN   Name=ANO3; Synonyms=C11orf25, TMEM16C; ORFNames=GENX-3947;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO4_HUMAN              Reviewed;         955 AA.
AC   Q32M45; Q8NAJ0; Q8NB39; Q8NB53;
DE   RecName: Full=Anoctamin-4;
DE   AltName: Full=Transmembrane protein 16D;
GN   Name=ANO4; Synonyms=TMEM16D;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO5_HUMAN              Reviewed;         913 AA.
AC   Q75V66;
DE   RecName: Full=Anoctamin-5;
DE   AltName: Full=Gnathodiaphyseal dysplasia 1 protein;
DE   AltName: Full=Transmembrane protein 16E;
GN   Name=ANO5; Synonyms=GDD1, TMEM16E;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO6_HUMAN              Reviewed;         910 AA.
AC   Q4KMQ2; A6NNM6; B9EGG0; E7ENK4; E9PB30; E9PCT2; Q8N3Q2;
DE   RecName: Full=Anoctamin-6;
DE   AltName: Full=Small-conductance calcium-activated nonselective cation channel;
DE            Short=SCAN channel;
DE   AltName: Full=Transmembrane protein 16F;
GN   Name=ANO6; Synonyms=TMEM16F;
DR   GO; GO:0005227; F:calcium activated cation channel activity; ISS:UniProtKB.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; ISS:UniProtKB.
DR   GO; GO:0002543; P:activation of blood coagulation via clotting cascade; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; ISS:UniProtKB.
DR   GO; GO:0006812; P:cation transport; ISS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0097045; P:phosphatidylserine exposure on blood platelet; IMP:UniProtKB.
DR   GO; GO:0017121; P:phospholipid scrambling; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO7_HUMAN              Reviewed;         933 AA.
AC   Q6IWH7; Q6IWH6;
DE   RecName: Full=Anoctamin-7;
DE   AltName: Full=Dresden transmembrane protein of the prostate;
DE            Short=D-TMPP;
DE   AltName: Full=IPCA-5;
DE   AltName: Full=New gene expressed in prostate;
DE   AltName: Full=Prostate cancer-associated protein 5;
DE   AltName: Full=Transmembrane protein 16G;
GN   Name=ANO7; Synonyms=NGEP, PCANAP5, TMEM16G;
DR   GO; GO:0005254; F:chloride channel activity; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO8_HUMAN              Reviewed;        1232 AA.
AC   Q9HCE9; A6NIJ0;
DE   RecName: Full=Anoctamin-8;
DE   AltName: Full=Transmembrane protein 16H;
GN   Name=ANO8; Synonyms=KIAA1623, TMEM16H;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANO9_HUMAN              Reviewed;         782 AA.
AC   A1A5B4; B3KUC4; B4E134; Q8TEN4;
DE   RecName: Full=Anoctamin-9;
DE   AltName: Full=Transmembrane protein 16J;
DE   AltName: Full=Tumor protein p53-inducible protein 5;
DE   AltName: Full=p53-induced gene 5 protein;
GN   Name=ANO9; Synonyms=PIG5, TMEM16J, TP53I5;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ANPRA_HUMAN             Reviewed;        1061 AA.
AC   P16066; B0ZBF0; Q5SR08; Q6P4Q3;
DE   RecName: Full=Atrial natriuretic peptide receptor 1;
DE            EC=4.6.1.2;
DE   AltName: Full=Atrial natriuretic peptide receptor type A;
DE            Short=ANP-A;
DE            Short=ANPR-A;
DE            Short=NPR-A;
DE   AltName: Full=Guanylate cyclase A;
DE            Short=GC-A;
DE   Flags: Precursor;
GN   Name=NPR1; Synonyms=ANPRA;
DR   GuidetoPHARMACOLOGY; 1747; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008528; F:G-protein coupled peptide receptor activity; NAS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0042562; F:hormone binding; IPI:UniProtKB.
DR   GO; GO:0016941; F:natriuretic peptide receptor activity; IDA:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0007589; P:body fluid secretion; TAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042417; P:dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; TAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; TAS:UniProtKB.
DR   GO; GO:0035810; P:positive regulation of urine volume; TAS:UniProtKB.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:UniProtKB-KW.
DR   GO; GO:0043114; P:regulation of vascular permeability; TAS:UniProtKB.
DR   GO; GO:0042312; P:regulation of vasodilation; NAS:UniProtKB.
//
ID   ANPRB_HUMAN             Reviewed;        1047 AA.
AC   P20594; B0ZBF2; B0ZBF3; D3DRP3; D3DRP4; O60871; Q4VAK7; Q5TCV2;
AC   Q8TA93; Q9UQ50;
DE   RecName: Full=Atrial natriuretic peptide receptor 2;
DE            EC=4.6.1.2;
DE   AltName: Full=Atrial natriuretic peptide receptor type B;
DE            Short=ANP-B;
DE            Short=ANPR-B;
DE            Short=NPR-B;
DE   AltName: Full=Guanylate cyclase B;
DE            Short=GC-B;
DE   Flags: Precursor;
GN   Name=NPR2; Synonyms=ANPRB;
DR   GuidetoPHARMACOLOGY; 1748; -.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0042562; F:hormone binding; IPI:UniProtKB.
DR   GO; GO:0016941; F:natriuretic peptide receptor activity; IDA:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0097011; P:cellular response to granulocyte macrophage colony-stimulating factor stimulus; IEP:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   ANPRC_HUMAN             Reviewed;         541 AA.
AC   P17342; A2RRD1; B4DT84; E7EPG9;
DE   RecName: Full=Atrial natriuretic peptide receptor 3;
DE   AltName: Full=Atrial natriuretic peptide clearance receptor;
DE   AltName: Full=Atrial natriuretic peptide receptor type C;
DE            Short=ANP-C;
DE            Short=ANPR-C;
DE            Short=NPR-C;
DE   Flags: Precursor;
GN   Name=NPR3; Synonyms=ANPRC, C5orf23, NPRC;
DR   GuidetoPHARMACOLOGY; 1749; -.
DR   GO; GO:0008528; F:G-protein coupled peptide receptor activity; ISS:BHF-UCL.
DR   GO; GO:0042562; F:hormone binding; IPI:UniProtKB.
DR   GO; GO:0016941; F:natriuretic peptide receptor activity; IDA:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; ISS:BHF-UCL.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0002158; P:osteoclast proliferation; ISS:UniProtKB.
DR   GO; GO:0030157; P:pancreatic juice secretion; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; ISS:BHF-UCL.
DR   GO; GO:0035810; P:positive regulation of urine volume; ISS:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0033688; P:regulation of osteoblast proliferation; ISS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; ISS:UniProtKB.
//
ID   ANR10_HUMAN             Reviewed;         420 AA.
AC   Q9NXR5; Q5VW12; Q9BV12;
DE   RecName: Full=Ankyrin repeat domain-containing protein 10;
GN   Name=ANKRD10;
//
ID   ANR11_HUMAN             Reviewed;        2663 AA.
AC   Q6UB99; Q6NTG1; Q6QMF8;
DE   RecName: Full=Ankyrin repeat domain-containing protein 11;
DE   AltName: Full=Ankyrin repeat-containing cofactor 1;
GN   Name=ANKRD11; Synonyms=ANCO1;
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IMP:MGI.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IMP:MGI.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
//
ID   ANR12_HUMAN             Reviewed;        2062 AA.
AC   Q6UB98; O94951; Q658K1; Q6QMF7; Q9H231; Q9H784;
DE   RecName: Full=Ankyrin repeat domain-containing protein 12;
DE   AltName: Full=Ankyrin repeat-containing cofactor 2;
DE   AltName: Full=GAC-1 protein;
GN   Name=ANKRD12; Synonyms=ANCO2, KIAA0874;
//
ID   ANR16_HUMAN             Reviewed;         361 AA.
AC   Q6P6B7; A6NEF0; F8WEI4; Q9NT01;
DE   RecName: Full=Ankyrin repeat domain-containing protein 16;
GN   Name=ANKRD16;
//
ID   ANR17_HUMAN             Reviewed;        2603 AA.
AC   O75179; E7EUV3; G5E964; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5;
AC   Q96I86; Q9H288; Q9H6J9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 17;
DE   AltName: Full=Gene trap ankyrin repeat protein;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-16;
GN   Name=ANKRD17; Synonyms=GTAR, KIAA0697;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001955; P:blood vessel maturation; IEA:Ensembl.
DR   GO; GO:0051151; P:negative regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ANR19_HUMAN             Reviewed;         264 AA.
AC   Q9H560; A8K853; Q17RD3;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 19;
DE   AltName: Full=Ankyrin repeat domain-containing protein 19 pseudogene;
GN   Name=ANKRD19P; Synonyms=ANKRD19;
//
ID   ANR22_HUMAN             Reviewed;         191 AA.
AC   Q5VYY1; B2R9Y7; Q8WU06;
DE   RecName: Full=Ankyrin repeat domain-containing protein 22;
GN   Name=ANKRD22;
//
ID   ANR23_HUMAN             Reviewed;         305 AA.
AC   Q86SG2; Q711K7; Q8NAJ7;
DE   RecName: Full=Ankyrin repeat domain-containing protein 23;
DE   AltName: Full=Diabetes-related ankyrin repeat protein;
DE   AltName: Full=Muscle ankyrin repeat protein 3;
GN   Name=ANKRD23; Synonyms=DARP;
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
//
ID   ANR24_HUMAN             Reviewed;        1146 AA.
AC   Q8TF21; O75268; O95781;
DE   RecName: Full=Ankyrin repeat domain-containing protein 24;
GN   Name=ANKRD24; Synonyms=KIAA1981;
//
ID   ANR26_HUMAN             Reviewed;        1709 AA.
AC   Q9UPS8; A6NH29; Q2TAZ3; Q6ZR14; Q9H1Q1; Q9NSK9; Q9NTD5; Q9NW69;
DE   RecName: Full=Ankyrin repeat domain-containing protein 26;
GN   Name=ANKRD26; Synonyms=KIAA1074;
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0060259; P:regulation of feeding behavior; IEA:Ensembl.
//
ID   ANR27_HUMAN             Reviewed;        1050 AA.
AC   Q96NW4; Q71MF5; Q86UC3; Q8ND80; Q9H0I4;
DE   RecName: Full=Ankyrin repeat domain-containing protein 27;
DE   AltName: Full=VPS9 domain-containing protein;
GN   Name=ANKRD27; ORFNames=PP12899;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IDA:MGI.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
//
ID   ANR28_HUMAN             Reviewed;        1053 AA.
AC   O15084; B4DES5; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A;
DE            Short=PP6-ARS-A;
DE            Short=Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A;
DE   AltName: Full=Ankyrin repeat domain-containing protein 28;
DE   AltName: Full=Phosphatase interactor targeting protein hnRNP K;
DE            Short=PITK;
GN   Name=ANKRD28; Synonyms=KIAA0379;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANR29_HUMAN             Reviewed;         301 AA.
AC   Q8N6D5; B2R972; Q6ZWE8; Q96LU9;
DE   RecName: Full=Ankyrin repeat domain-containing protein 29;
GN   Name=ANKRD29;
//
ID   ANR31_HUMAN             Reviewed;        1873 AA.
AC   Q8N7Z5;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 31;
GN   Name=ANKRD31;
//
ID   ANR32_HUMAN             Reviewed;        1058 AA.
AC   Q9BQI6; Q3B7K4; Q6NSA5; Q6PHW9; Q9Y402;
DE   RecName: Full=Ankyrin repeat domain-containing protein 32;
DE   AltName: Full=BRCT domain-containing protein 1;
GN   Name=ANKRD32; Synonyms=BRCTD1;
//
ID   ANR33_HUMAN             Reviewed;         272 AA.
AC   Q7Z3H0; Q0VAA7; Q5K619; Q5K621; Q5K622; Q5K623; Q5K624; Q6ZUN0;
DE   RecName: Full=Ankyrin repeat domain-containing protein 33;
GN   Name=ANKRD33; Synonyms=C12orf7;
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   ANR35_HUMAN             Reviewed;        1001 AA.
AC   Q8N283; A6NEU0; Q3MJ10; Q96LS3;
DE   RecName: Full=Ankyrin repeat domain-containing protein 35;
GN   Name=ANKRD35;
//
ID   ANR37_HUMAN             Reviewed;         158 AA.
AC   Q7Z713;
DE   RecName: Full=Ankyrin repeat domain-containing protein 37;
DE   AltName: Full=Low-density lipoprotein receptor-related protein 2-binding protein;
DE            Short=hLrp2bp;
GN   Name=ANKRD37; Synonyms=LPR2BP;
//
ID   ANR39_HUMAN             Reviewed;         183 AA.
AC   Q53RE8; Q59FU2; Q8N5X5; Q9P0S5;
DE   RecName: Full=Ankyrin repeat domain-containing protein 39;
GN   Name=ANKRD39; ORFNames=HSPC200;
//
ID   ANR40_HUMAN             Reviewed;         368 AA.
AC   Q6AI12; Q96E32;
DE   RecName: Full=Ankyrin repeat domain-containing protein 40;
GN   Name=ANKRD40;
//
ID   ANR42_HUMAN             Reviewed;         389 AA.
AC   Q8N9B4; Q49A49;
DE   RecName: Full=Ankyrin repeat domain-containing protein 42;
GN   Name=ANKRD42;
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
//
ID   ANR44_HUMAN             Reviewed;         993 AA.
AC   Q8N8A2; Q53SL9; Q6P480; Q86VL5; Q8IZ72; Q9UFA4;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B;
DE            Short=PP6-ARS-B;
DE            Short=Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B;
DE   AltName: Full=Ankyrin repeat domain-containing protein 44;
GN   Name=ANKRD44;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANR45_HUMAN             Reviewed;         282 AA.
AC   Q5TZF3; A1A4G2; Q6ZST1;
DE   RecName: Full=Ankyrin repeat domain-containing protein 45;
GN   Name=ANKRD45;
//
ID   ANR46_HUMAN             Reviewed;         232 AA.
AC   Q86W74; Q6P9B7;
DE   RecName: Full=Ankyrin repeat domain-containing protein 46;
DE   AltName: Full=Ankyrin repeat small protein;
DE            Short=ANK-S;
GN   Name=ANKRD46;
//
ID   ANR49_HUMAN             Reviewed;         239 AA.
AC   Q8WVL7; Q8NDF2; Q96JE5; Q9NXK7;
DE   RecName: Full=Ankyrin repeat domain-containing protein 49;
DE   AltName: Full=Fetal globin-inducing factor;
GN   Name=ANKRD49; Synonyms=FGIF;
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   ANR50_HUMAN             Reviewed;        1429 AA.
AC   Q9ULJ7; A8K4V3; B4DHJ6; E9PDW0; Q6N064; Q6ZSE6;
DE   RecName: Full=Ankyrin repeat domain-containing protein 50;
GN   Name=ANKRD50; Synonyms=KIAA1223;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANR52_HUMAN             Reviewed;        1076 AA.
AC   Q8NB46; A6NE79; B1Q2K2;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C;
DE            Short=PP6-ARS-C;
DE            Short=Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C;
DE   AltName: Full=Ankyrin repeat domain-containing protein 52;
GN   Name=ANKRD52;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ANR53_HUMAN             Reviewed;         530 AA.
AC   Q8N9V6; Q8IYP8;
DE   RecName: Full=Ankyrin repeat domain-containing protein 53;
GN   Name=ANKRD53;
//
ID   ANR54_HUMAN             Reviewed;         300 AA.
AC   Q6NXT1; Q6ZSB1; Q9UGV1;
DE   RecName: Full=Ankyrin repeat domain-containing protein 54;
DE   AltName: Full=Lyn-interacting ankyrin repeat protein;
GN   Name=ANKRD54; Synonyms=LIAR;
DR   GO; GO:0019887; F:protein kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:1902531; P:regulation of intracellular signal transduction; ISS:UniProtKB.
//
ID   ANR55_HUMAN             Reviewed;         614 AA.
AC   Q3KP44; B3KVT8; Q3KP45; Q9HAD3;
DE   RecName: Full=Ankyrin repeat domain-containing protein 55;
GN   Name=ANKRD55;
//
ID   ANR60_HUMAN             Reviewed;         345 AA.
AC   Q9BZ19; Q4VXE6;
DE   RecName: Full=Ankyrin repeat domain-containing protein 60;
GN   Name=ANKRD60; Synonyms=C20orf86;
//
ID   ANR61_HUMAN             Reviewed;         418 AA.
AC   A6NGH8;
DE   RecName: Full=Ankyrin repeat domain-containing protein 61;
GN   Name=ANKRD61;
//
ID   ANR62_HUMAN             Reviewed;         917 AA.
AC   A6NC57;
DE   RecName: Full=Ankyrin repeat domain-containing protein 62;
GN   Name=ANKRD62;
//
ID   ANR63_HUMAN             Reviewed;         380 AA.
AC   C9JTQ0;
DE   RecName: Full=Ankyrin repeat domain-containing protein 63;
GN   Name=ANKRD63;
//
ID   ANR65_HUMAN             Reviewed;         399 AA.
AC   E5RJM6; J3KR93;
DE   RecName: Full=Ankyrin repeat domain-containing protein 65;
GN   Name=ANKRD65;
//
ID   ANR66_HUMAN             Reviewed;         251 AA.
AC   B4E2M5;
DE   RecName: Full=Ankyrin repeat domain-containing protein 66;
GN   Name=ANKRD66;
//
ID   ANRA2_HUMAN             Reviewed;         313 AA.
AC   Q9H9E1;
DE   RecName: Full=Ankyrin repeat family A protein 2;
DE   AltName: Full=RFXANK-like protein 2;
GN   Name=ANKRA2; Synonyms=ANKRA;
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:UniProtKB.
//
ID   ANRE_HUMAN              Reviewed;         121 AA.
AC   P61109; P15267;
DE   RecName: Full=Kidney androgen-regulated protein;
DE            Short=ARP;
DE            Short=KAP;
DE   Flags: Precursor;
GN   Name=KAP; ORFNames=FKSG22;
//
ID   ANS1A_HUMAN             Reviewed;        1134 AA.
AC   Q92625; A2RUC1; Q5JYI9; Q5SYR2; Q86WQ7;
DE   RecName: Full=Ankyrin repeat and SAM domain-containing protein 1A;
DE   AltName: Full=Odin;
GN   Name=ANKS1A; Synonyms=ANKS1, KIAA0229, ODIN;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016322; P:neuron remodeling; ISS:UniProtKB.
DR   GO; GO:0006929; P:substrate-dependent cell migration; ISS:UniProtKB.
//
ID   ANS1B_HUMAN             Reviewed;        1248 AA.
AC   Q7Z6G8; A5PKY5; A7E259; A8K153; A8MSN4; B4DFP6; B4DH98; F8VPM3;
AC   F8VZR9; F8WC27; Q5XLJ0; Q6IVB5; Q6NUS4; Q7Z6G6; Q7Z6G7; Q8TAP3;
AC   Q9NRX7; Q9Y5K9;
DE   RecName: Full=Ankyrin repeat and sterile alpha motif domain-containing protein 1B;
DE   AltName: Full=Amyloid-beta protein intracellular domain-associated protein 1;
DE            Short=AIDA-1;
DE   AltName: Full=E2A-PBX1-associated protein;
DE            Short=EB-1;
GN   Name=ANKS1B;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
//
ID   ANS4B_HUMAN             Reviewed;         417 AA.
AC   Q8N8V4;
DE   RecName: Full=Ankyrin repeat and SAM domain-containing protein 4B;
DE   AltName: Full=Harmonin-interacting ankyrin repeat-containing protein;
DE            Short=Harp;
GN   Name=ANKS4B; Synonyms=HARP;
//
ID   ANT3_HUMAN              Reviewed;         464 AA.
AC   P01008; B2R6P0; P78439; P78447; Q13815; Q5TC78; Q7KZ43; Q7KZ97;
AC   Q9UC78;
DE   RecName: Full=Antithrombin-III;
DE            Short=ATIII;
DE   AltName: Full=Serpin C1;
DE   Flags: Precursor;
GN   Name=SERPINC1; Synonyms=AT3; ORFNames=PRO0309;
DR   GuidetoPHARMACOLOGY; 2632; -.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:2000266; P:regulation of blood coagulation, intrinsic pathway; IEA:InterPro.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   ANTR1_HUMAN             Reviewed;         564 AA.
AC   Q9H6X2; A8K7U8; J7K7G4; J7KF88; Q4ZFV6; Q53QD8; Q96P02; Q9NVP3;
DE   RecName: Full=Anthrax toxin receptor 1;
DE   AltName: Full=Tumor endothelial marker 8;
DE   Flags: Precursor;
GN   Name=ANTXR1; Synonyms=ATR, TEM8;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0022414; P:reproductive process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:GOC.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.
//
ID   ANTR2_HUMAN             Reviewed;         489 AA.
AC   P58335; Q4W5H6; Q59E98; Q5JPE9; Q86UI1; Q8N4J8; Q8NB13; Q96NC7;
DE   RecName: Full=Anthrax toxin receptor 2;
DE   AltName: Full=Capillary morphogenesis gene 2 protein;
DE            Short=CMG-2;
DE   Flags: Precursor;
GN   Name=ANTXR2; Synonyms=CMG2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0022414; P:reproductive process; IEA:Ensembl.
//
ID   ANTRL_HUMAN             Reviewed;         631 AA.
AC   A6NF34; H3BPS2;
DE   RecName: Full=Anthrax toxin receptor-like;
DE   Flags: Precursor;
GN   Name=ANTXRL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
//
ID   ANX10_HUMAN             Reviewed;         324 AA.
AC   Q9UJ72; Q96IQ5; Q9UJV4;
DE   RecName: Full=Annexin A10;
DE   AltName: Full=Annexin-10;
DE   AltName: Full=Annexin-14;
GN   Name=ANXA10; Synonyms=ANX14;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:InterPro.
//
ID   ANX11_HUMAN             Reviewed;         505 AA.
AC   P50995; B4DVE7;
DE   RecName: Full=Annexin A11;
DE   AltName: Full=56 kDa autoantigen;
DE   AltName: Full=Annexin XI;
DE   AltName: Full=Annexin-11;
DE   AltName: Full=Calcyclin-associated annexin 50;
DE            Short=CAP-50;
GN   Name=ANXA11; Synonyms=ANX11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0008429; F:phosphatidylethanolamine binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0007109; P:cytokinesis, completion of separation; IMP:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IEP:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
//
ID   ANX13_HUMAN             Reviewed;         316 AA.
AC   P27216; Q9BQR5;
DE   RecName: Full=Annexin A13;
DE   AltName: Full=Annexin XIII;
DE   AltName: Full=Annexin-13;
DE   AltName: Full=Intestine-specific annexin;
DE            Short=ISA;
GN   Name=ANXA13; Synonyms=ANX13;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
DR   GO; GO:1901611; F:phosphatidylglycerol binding; IDA:UniProt.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProt.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; ISS:UniProt.
DR   GO; GO:0042998; P:positive regulation of Golgi to plasma membrane protein transport; ISS:UniProt.
//
ID   ANXA1_HUMAN             Reviewed;         346 AA.
AC   P04083;
DE   RecName: Full=Annexin A1;
DE   AltName: Full=Annexin I;
DE   AltName: Full=Annexin-1;
DE   AltName: Full=Calpactin II;
DE   AltName: Full=Calpactin-2;
DE   AltName: Full=Chromobindin-9;
DE   AltName: Full=Lipocortin I;
DE   AltName: Full=Phospholipase A2 inhibitory protein;
DE   AltName: Full=p35;
GN   Name=ANXA1; Synonyms=ANX1, LPC1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0019834; F:phospholipase A2 inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0046632; P:alpha-beta T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IDA:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0060206; P:estrous cycle phase; IEA:Ensembl.
DR   GO; GO:0042063; P:gliogenesis; IEA:Ensembl.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0097350; P:neutrophil clearance; IMP:BHF-UCL.
DR   GO; GO:0001780; P:neutrophil homeostasis; IMP:BHF-UCL.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0033031; P:positive regulation of neutrophil apoptotic process; IEA:Ensembl.
DR   GO; GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   ANXA2_HUMAN             Reviewed;         339 AA.
AC   P07355; Q567R4; Q6N0B3; Q8TBV2; Q96DD5; Q9UDH8;
DE   RecName: Full=Annexin A2;
DE   AltName: Full=Annexin II;
DE   AltName: Full=Annexin-2;
DE   AltName: Full=Calpactin I heavy chain;
DE   AltName: Full=Calpactin-1 heavy chain;
DE   AltName: Full=Chromobindin-8;
DE   AltName: Full=Lipocortin II;
DE   AltName: Full=Placental anticoagulant protein IV;
DE            Short=PAP-IV;
DE   AltName: Full=Protein I;
DE   AltName: Full=p36;
GN   Name=ANXA2; Synonyms=ANX2, ANX2L4, CAL1H, LPC2D;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IMP:UniProt.
DR   GO; GO:0019834; F:phospholipase A2 inhibitor activity; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProt.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0007589; P:body fluid secretion; IEA:Ensembl.
DR   GO; GO:0071229; P:cellular response to acid; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0042730; P:fibrinolysis; IEA:Ensembl.
DR   GO; GO:0006900; P:membrane budding; IMP:UniProt.
DR   GO; GO:0001765; P:membrane raft assembly; IMP:UniProt.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0036035; P:osteoclast development; IDA:UniProt.
DR   GO; GO:0051099; P:positive regulation of binding; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; IDA:UniProtKB.
DR   GO; GO:0051290; P:protein heterotetramerization; IDA:UniProt.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IEA:Ensembl.
//
ID   ANXA3_HUMAN             Reviewed;         323 AA.
AC   P12429; B2R9W6; Q6LET2;
DE   RecName: Full=Annexin A3;
DE   AltName: Full=35-alpha calcimedin;
DE   AltName: Full=Annexin III;
DE   AltName: Full=Annexin-3;
DE   AltName: Full=Inositol 1,2-cyclic phosphate 2-phosphohydrolase;
DE   AltName: Full=Lipocortin III;
DE   AltName: Full=Placental anticoagulant protein III;
DE            Short=PAP-III;
GN   Name=ANXA3; Synonyms=ANX3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0019834; F:phospholipase A2 inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR   GO; GO:0043312; P:neutrophil degranulation; IDA:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
//
ID   ANXA4_HUMAN             Reviewed;         319 AA.
AC   P09525; Q96F33; Q9BWK1;
DE   RecName: Full=Annexin A4;
DE   AltName: Full=35-beta calcimedin;
DE   AltName: Full=Annexin IV;
DE   AltName: Full=Annexin-4;
DE   AltName: Full=Carbohydrate-binding protein p33/p41;
DE   AltName: Full=Chromobindin-4;
DE   AltName: Full=Endonexin I;
DE   AltName: Full=Lipocortin IV;
DE   AltName: Full=P32.5;
DE   AltName: Full=PP4-X;
DE   AltName: Full=Placental anticoagulant protein II;
DE            Short=PAP-II;
DE   AltName: Full=Protein II;
GN   Name=ANXA4; Synonyms=ANX4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0004859; F:phospholipase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   ANXA5_HUMAN             Reviewed;         320 AA.
AC   P08758; D3DNW7; Q6FHB3; Q6FI16; Q8WV69; Q9UDH9;
DE   RecName: Full=Annexin A5;
DE   AltName: Full=Anchorin CII;
DE   AltName: Full=Annexin V;
DE   AltName: Full=Annexin-5;
DE   AltName: Full=Calphobindin I;
DE            Short=CBP-I;
DE   AltName: Full=Endonexin II;
DE   AltName: Full=Lipocortin V;
DE   AltName: Full=Placental anticoagulant protein 4;
DE            Short=PP4;
DE   AltName: Full=Placental anticoagulant protein I;
DE            Short=PAP-I;
DE   AltName: Full=Thromboplastin inhibitor;
DE   AltName: Full=Vascular anticoagulant-alpha;
DE            Short=VAC-alpha;
GN   Name=ANXA5; Synonyms=ANX5, ENX2, PP4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0004859; F:phospholipase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0050819; P:negative regulation of coagulation; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   ANXA6_HUMAN             Reviewed;         673 AA.
AC   P08133; B7Z8A7; D3DQH4; E9PGK1; Q6ZT79;
DE   RecName: Full=Annexin A6;
DE   AltName: Full=67 kDa calelectrin;
DE   AltName: Full=Annexin VI;
DE   AltName: Full=Annexin-6;
DE   AltName: Full=Calphobindin-II;
DE            Short=CPB-II;
DE   AltName: Full=Chromobindin-20;
DE   AltName: Full=Lipocortin VI;
DE   AltName: Full=Protein III;
DE   AltName: Full=p68;
DE   AltName: Full=p70;
GN   Name=ANXA6; Synonyms=ANX6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:Ensembl.
//
ID   ANXA7_HUMAN             Reviewed;         488 AA.
AC   P20073; Q5F2H3; Q5T0M6; Q5T0M7;
DE   RecName: Full=Annexin A7;
DE   AltName: Full=Annexin VII;
DE   AltName: Full=Annexin-7;
DE   AltName: Full=Synexin;
GN   Name=ANXA7; Synonyms=ANX7, SNX; ORFNames=OK/SW-cl.95;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0009992; P:cellular water homeostasis; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0007599; P:hemostasis; IEA:Ensembl.
DR   GO; GO:0061025; P:membrane fusion; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEP:UniProtKB.
//
ID   ANXA8_HUMAN             Reviewed;         327 AA.
AC   P13928; A6NLM1; Q5VTM4; Q6GMY3; Q9BT34;
DE   RecName: Full=Annexin A8;
DE   AltName: Full=Annexin VIII;
DE   AltName: Full=Annexin-8;
DE   AltName: Full=Vascular anticoagulant-beta;
DE            Short=VAC-beta;
GN   Name=ANXA8; Synonyms=ANX8;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProt.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProt.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProt.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProt.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProt.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProt.
DR   GO; GO:1900138; P:negative regulation of phospholipase A2 activity; IDA:UniProt.
DR   GO; GO:1900004; P:negative regulation of serine-type endopeptidase activity; IDA:UniProt.
//
ID   ANXA9_HUMAN             Reviewed;         345 AA.
AC   O76027; Q5SZF1; Q6FI55; Q9BS00; Q9HBJ6;
DE   RecName: Full=Annexin A9;
DE   AltName: Full=Annexin XXXI;
DE   AltName: Full=Annexin-31;
DE   AltName: Full=Annexin-9;
DE   AltName: Full=Pemphaxin;
GN   Name=ANXA9; Synonyms=ANX31;
DR   GO; GO:0015464; F:acetylcholine receptor activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:InterPro.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; IDA:GOC.
//
ID   AOAH_HUMAN              Reviewed;         575 AA.
AC   P28039; A4D1Y5; B7Z490; Q53F13;
DE   RecName: Full=Acyloxyacyl hydrolase;
DE            EC=3.1.1.77;
DE   Contains:
DE     RecName: Full=Acyloxyacyl hydrolase small subunit;
DE   Contains:
DE     RecName: Full=Acyloxyacyl hydrolase large subunit;
DE   Flags: Precursor;
GN   Name=AOAH;
DR   GO; GO:0050528; F:acyloxyacyl hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0004465; F:lipoprotein lipase activity; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0008653; P:lipopolysaccharide metabolic process; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
//
ID   AOC1_HUMAN              Reviewed;         751 AA.
AC   P19801; Q16683; Q16684; Q56II4; Q6GU42;
DE   RecName: Full=Amiloride-sensitive amine oxidase [copper-containing];
DE            Short=DAO;
DE            Short=Diamine oxidase;
DE            EC=1.4.3.22;
DE   AltName: Full=Amiloride-binding protein 1;
DE   AltName: Full=Amine oxidase copper domain-containing protein 1;
DE   AltName: Full=Histaminase;
DE   AltName: Full=Kidney amine oxidase;
DE            Short=KAO;
DE   Flags: Precursor;
GN   Name=AOC1; Synonyms=ABP1, DAO1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005261; F:cation channel activity; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0052597; F:diamine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0052598; F:histamine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052599; F:methylputrescine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008131; F:primary amine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0052600; F:propane-1,3-diamine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0005272; F:sodium channel activity; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009308; P:amine metabolic process; IEA:InterPro.
DR   GO; GO:0097185; P:cellular response to azide; IDA:UniProtKB.
DR   GO; GO:0071280; P:cellular response to copper ion; IDA:UniProtKB.
DR   GO; GO:0035874; P:cellular response to copper ion starvation; IDA:UniProtKB.
DR   GO; GO:0071504; P:cellular response to heparin; TAS:UniProtKB.
DR   GO; GO:0071420; P:cellular response to histamine; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:UniProtKB.
//
ID   AOC2_HUMAN              Reviewed;         756 AA.
AC   O75106; A5PKW2; O00120; O75105; Q4TTW5; Q9UNY0;
DE   RecName: Full=Retina-specific copper amine oxidase;
DE            Short=RAO;
DE            EC=1.4.3.21;
DE   AltName: Full=Amine oxidase [copper-containing];
DE   AltName: Full=Semicarbazide-sensitive amine oxidase;
DE            Short=SSAO;
DE   Flags: Precursor;
GN   Name=AOC2;
DR   GO; GO:0052595; F:aliphatic-amine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052594; F:aminoacetone:oxygen oxidoreductase(deaminating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0052596; F:phenethylamine:oxygen oxidoreductase (deaminating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008131; F:primary amine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0052593; F:tryptamine:oxygen oxidoreductase (deaminating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0009308; P:amine metabolic process; IEA:InterPro.
DR   GO; GO:0006584; P:catecholamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   AOC3_HUMAN              Reviewed;         763 AA.
AC   Q16853; B2RCI5; L0L8N9; Q45F94;
DE   RecName: Full=Membrane primary amine oxidase;
DE            EC=1.4.3.21;
DE   AltName: Full=Copper amine oxidase;
DE   AltName: Full=HPAO;
DE   AltName: Full=Semicarbazide-sensitive amine oxidase;
DE            Short=SSAO;
DE   AltName: Full=Vascular adhesion protein 1;
DE            Short=VAP-1;
GN   Name=AOC3; Synonyms=VAP1;
DR   GO; GO:0052595; F:aliphatic-amine oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052594; F:aminoacetone:oxygen oxidoreductase(deaminating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005261; F:cation channel activity; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0052596; F:phenethylamine:oxygen oxidoreductase (deaminating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008131; F:primary amine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IDA:UniProtKB.
DR   GO; GO:0052593; F:tryptamine:oxygen oxidoreductase (deaminating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0009308; P:amine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IDA:UniProtKB.
//
ID   AOFA_HUMAN              Reviewed;         527 AA.
AC   P21397; B4DF46; Q16426;
DE   RecName: Full=Amine oxidase [flavin-containing] A;
DE            EC=1.4.3.4;
DE   AltName: Full=Monoamine oxidase type A;
DE            Short=MAO-A;
GN   Name=MAOA;
DR   GuidetoPHARMACOLOGY; 2489; -.
DR   GO; GO:0008131; F:primary amine oxidase activity; TAS:Reactome.
DR   GO; GO:0006576; P:cellular biogenic amine metabolic process; TAS:ProtInc.
DR   GO; GO:0042420; P:dopamine catabolic process; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   AOFB_HUMAN              Reviewed;         520 AA.
AC   P27338; B2R6R3; D3DWC3; Q7Z6S2;
DE   RecName: Full=Amine oxidase [flavin-containing] B;
DE            EC=1.4.3.4;
DE   AltName: Full=Monoamine oxidase type B;
DE            Short=MAO-B;
GN   Name=MAOB;
DR   GuidetoPHARMACOLOGY; 2490; -.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0008131; F:primary amine oxidase activity; TAS:Reactome.
DR   GO; GO:0014063; P:negative regulation of serotonin secretion; IEA:Ensembl.
DR   GO; GO:0045964; P:positive regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0010044; P:response to aluminum ion; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010269; P:response to selenium ion; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   AOXA_HUMAN              Reviewed;        1338 AA.
AC   Q06278; O14765; Q53RR8; Q53TV3; Q9BYF0; Q9UPG6;
DE   RecName: Full=Aldehyde oxidase;
DE            EC=1.2.3.1;
DE   AltName: Full=Aldehyde oxidase 1;
DE   AltName: Full=Azaheterocycle hydroxylase;
DE            EC=1.17.3.-;
GN   Name=AOX1; Synonyms=AO;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004031; F:aldehyde oxidase activity; TAS:Reactome.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0004854; F:xanthine dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042816; P:vitamin B6 metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   AP180_HUMAN             Reviewed;         907 AA.
AC   O60641; A8K0L7; E5RI02; Q5JX13; Q68DL9; Q6P9D3; Q9NTY7;
DE   RecName: Full=Clathrin coat assembly protein AP180;
DE   AltName: Full=91 kDa synaptosomal-associated protein;
DE   AltName: Full=Clathrin coat-associated protein AP180;
DE   AltName: Full=Phosphoprotein F1-20;
GN   Name=SNAP91; Synonyms=KIAA0656;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AP1AR_HUMAN             Reviewed;         302 AA.
AC   Q63HQ0; B2RCV7; Q96GG6; Q9H0V0; Q9P1L4;
DE   RecName: Full=AP-1 complex-associated regulatory protein;
DE   AltName: Full=2c18;
DE   AltName: Full=Adapter-related protein complex 1-associated regulatory protein;
DE   AltName: Full=Gamma-1-adaptin brefeldin A resistance protein;
DE            Short=GBAR;
DE            Short=Gamma-BAR;
DE   AltName: Full=Gamma-A1-adaptin and kinesin interactor;
DE            Short=Gadkin;
GN   Name=AP1AR; Synonyms=C4orf16; ORFNames=PRO0971;
DR   GO; GO:0035650; F:AP-1 adaptor complex binding; IDA:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; IDA:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:2000146; P:negative regulation of cell motility; IEA:Ensembl.
DR   GO; GO:0001920; P:negative regulation of receptor recycling; IMP:UniProtKB.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IMP:MGI.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0034315; P:regulation of Arp2/3 complex-mediated actin nucleation; IEA:Ensembl.
DR   GO; GO:0048203; P:vesicle targeting, trans-Golgi to endosome; IDA:UniProtKB.
//
ID   AP1B1_HUMAN             Reviewed;         949 AA.
AC   Q10567; C9JRD1; F8WDL0; P78436; Q20WL3; Q86X54;
DE   RecName: Full=AP-1 complex subunit beta-1;
DE   AltName: Full=Adapter-related protein complex 1 subunit beta-1;
DE   AltName: Full=Adaptor protein complex AP-1 subunit beta-1;
DE   AltName: Full=Beta-1-adaptin;
DE   AltName: Full=Beta-adaptin 1;
DE   AltName: Full=Clathrin assembly protein complex 1 beta large chain;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin beta subunit;
GN   Name=AP1B1; Synonyms=ADTB1, BAM22, CLAPB2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP1G1_HUMAN             Reviewed;         822 AA.
AC   O43747; O75709; O75842; Q9UG09; Q9Y3U4;
DE   RecName: Full=AP-1 complex subunit gamma-1;
DE   AltName: Full=Adapter-related protein complex 1 subunit gamma-1;
DE   AltName: Full=Adaptor protein complex AP-1 subunit gamma-1;
DE   AltName: Full=Clathrin assembly protein complex 1 gamma-1 large chain;
DE   AltName: Full=Gamma1-adaptin;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin subunit gamma-1;
GN   Name=AP1G1; Synonyms=ADTG, CLAPG1;
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0090160; P:Golgi to lysosome transport; IMP:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043323; P:positive regulation of natural killer cell degranulation; IMP:UniProt.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IMP:UniProt.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP1G2_HUMAN             Reviewed;         785 AA.
AC   O75843; D3DS51; O75504;
DE   RecName: Full=AP-1 complex subunit gamma-like 2;
DE   AltName: Full=Gamma2-adaptin;
DE            Short=G2ad;
GN   Name=AP1G2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   AP1M1_HUMAN             Reviewed;         423 AA.
AC   Q9BXS5; Q4TTY5;
DE   RecName: Full=AP-1 complex subunit mu-1;
DE   AltName: Full=AP-mu chain family member mu1A;
DE   AltName: Full=Adapter-related protein complex 1 subunit mu-1;
DE   AltName: Full=Adaptor protein complex AP-1 subunit mu-1;
DE   AltName: Full=Clathrin assembly protein complex 1 mu-1 medium chain 1;
DE   AltName: Full=Clathrin coat assembly protein AP47;
DE   AltName: Full=Clathrin coat-associated protein AP47;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin mu-1 subunit;
DE   AltName: Full=Mu-adaptin 1;
DE   AltName: Full=Mu1A-adaptin;
GN   Name=AP1M1; Synonyms=CLTNM;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0035646; P:endosome to melanosome transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0032438; P:melanosome organization; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP1M2_HUMAN             Reviewed;         423 AA.
AC   Q9Y6Q5; B2RDV5; Q9BSI8;
DE   RecName: Full=AP-1 complex subunit mu-2;
DE   AltName: Full=AP-mu chain family member mu1B;
DE   AltName: Full=Adaptor protein complex AP-1 subunit mu-2;
DE   AltName: Full=Adaptor-related protein complex 1 subunit mu-2;
DE   AltName: Full=Clathrin assembly protein complex 1 mu-2 medium chain 2;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin mu-2 subunit;
DE   AltName: Full=Mu-adaptin 2;
DE   AltName: Full=Mu1B-adaptin;
GN   Name=AP1M2;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006605; P:protein targeting; TAS:ProtInc.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0006903; P:vesicle targeting; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP1S1_HUMAN             Reviewed;         158 AA.
AC   P61966; B2R5D8; P82267; Q00382; Q53YA7; Q9BTN4; Q9UDW9;
DE   RecName: Full=AP-1 complex subunit sigma-1A;
DE   AltName: Full=Adapter-related protein complex 1 subunit sigma-1A;
DE   AltName: Full=Adaptor protein complex AP-1 subunit sigma-1A;
DE   AltName: Full=Clathrin assembly protein complex 1 sigma-1A small chain;
DE   AltName: Full=Clathrin coat assembly protein AP19;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin sigma-1A subunit;
DE   AltName: Full=HA1 19 kDa subunit;
DE   AltName: Full=Sigma 1a subunit of AP-1 clathrin;
DE   AltName: Full=Sigma-adaptin 1A;
DE   AltName: Full=Sigma1A-adaptin;
GN   Name=AP1S1; Synonyms=AP19, CLAPS1;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP1S2_HUMAN             Reviewed;         157 AA.
AC   P56377; B4DSU4; O95326; Q9H2N6;
DE   RecName: Full=AP-1 complex subunit sigma-2;
DE   AltName: Full=Adapter-related protein complex 1 subunit sigma-1B;
DE   AltName: Full=Adaptor protein complex AP-1 subunit sigma-1B;
DE   AltName: Full=Clathrin assembly protein complex 1 sigma-1B small chain;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin sigma-1B subunit;
DE   AltName: Full=Sigma 1B subunit of AP-1 clathrin;
DE   AltName: Full=Sigma-adaptin 1B;
DE   AltName: Full=Sigma1B-adaptin;
GN   Name=AP1S2; ORFNames=DC22;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP1S3_HUMAN             Reviewed;         154 AA.
AC   Q96PC3; B4DQZ1; Q8WTY1; Q96DD1;
DE   RecName: Full=AP-1 complex subunit sigma-3;
DE   AltName: Full=Adapter-related protein complex 1 subunit sigma-1C;
DE   AltName: Full=Adaptor protein complex AP-1 subunit sigma-1C;
DE   AltName: Full=Clathrin assembly protein complex 1 sigma-1C small chain;
DE   AltName: Full=Golgi adaptor HA1/AP1 adaptin sigma-1C subunit;
DE   AltName: Full=Sigma 1C subunit of AP-1 clathrin;
DE   AltName: Full=Sigma-adaptin 1C;
DE   AltName: Full=Sigma1C-adaptin;
GN   Name=AP1S3;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP2A1_HUMAN             Reviewed;         977 AA.
AC   O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070;
DE   RecName: Full=AP-2 complex subunit alpha-1;
DE   AltName: Full=100 kDa coated vesicle protein A;
DE   AltName: Full=Adapter-related protein complex 2 subunit alpha-1;
DE   AltName: Full=Adaptor protein complex AP-2 subunit alpha-1;
DE   AltName: Full=Alpha-adaptin A;
DE   AltName: Full=Alpha1-adaptin;
DE   AltName: Full=Clathrin assembly protein complex 2 alpha-A large chain;
DE   AltName: Full=Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit;
GN   Name=AP2A1; Synonyms=ADTAA, CLAPA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006895; P:Golgi to endosome transport; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:1900126; P:negative regulation of hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP2A2_HUMAN             Reviewed;         939 AA.
AC   O94973; O75403; Q53ET1; Q96SI8;
DE   RecName: Full=AP-2 complex subunit alpha-2;
DE   AltName: Full=100 kDa coated vesicle protein C;
DE   AltName: Full=Adapter-related protein complex 2 subunit alpha-2;
DE   AltName: Full=Adaptor protein complex AP-2 subunit alpha-2;
DE   AltName: Full=Alpha-adaptin C;
DE   AltName: Full=Alpha2-adaptin;
DE   AltName: Full=Clathrin assembly protein complex 2 alpha-C large chain;
DE   AltName: Full=Huntingtin yeast partner J;
DE   AltName: Full=Huntingtin-interacting protein 9;
DE            Short=HIP-9;
DE   AltName: Full=Huntingtin-interacting protein J;
DE   AltName: Full=Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit;
GN   Name=AP2A2; Synonyms=ADTAB, CLAPA2, HIP9, HYPJ, KIAA0899;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP2A_HUMAN              Reviewed;         437 AA.
AC   P05549; Q13777; Q5TAV5; Q8N1C6;
DE   RecName: Full=Transcription factor AP-2-alpha;
DE            Short=AP2-alpha;
DE   AltName: Full=AP-2 transcription factor;
DE   AltName: Full=Activating enhancer-binding protein 2-alpha;
DE   AltName: Full=Activator protein 2;
DE            Short=AP-2;
GN   Name=TFAP2A; Synonyms=AP2TF, TFAP2;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0021506; P:anterior neuropore closure; IEA:Ensembl.
DR   GO; GO:0071711; P:basement membrane organization; IEA:Ensembl.
DR   GO; GO:0060349; P:bone morphogenesis; ISS:UniProtKB.
DR   GO; GO:0071281; P:cellular response to iron ion; IDA:UniProtKB.
DR   GO; GO:0061303; P:cornea development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0010172; P:embryonic body morphogenesis; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0048730; P:epidermis morphogenesis; IEA:Ensembl.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IMP:UniProtKB.
DR   GO; GO:0003334; P:keratinocyte development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IMP:UniProtKB.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0072210; P:metanephric nephron development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0021623; P:oculomotor nerve formation; ISS:UniProtKB.
DR   GO; GO:0003409; P:optic cup structural organization; ISS:UniProtKB.
DR   GO; GO:0003404; P:optic vesicle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IMP:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0070172; P:positive regulation of tooth mineralization; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010842; P:retina layer formation; IEP:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0021559; P:trigeminal nerve development; ISS:UniProtKB.
//
ID   AP2B1_HUMAN             Reviewed;         937 AA.
AC   P63010; A6NJP3; P21851; Q7Z451; Q96J19;
DE   RecName: Full=AP-2 complex subunit beta;
DE   AltName: Full=AP105B;
DE   AltName: Full=Adapter-related protein complex 2 subunit beta;
DE   AltName: Full=Adaptor protein complex AP-2 subunit beta;
DE   AltName: Full=Beta-2-adaptin;
DE   AltName: Full=Beta-adaptin;
DE   AltName: Full=Clathrin assembly protein complex 2 beta large chain;
DE   AltName: Full=Plasma membrane adaptor HA2/AP2 adaptin beta subunit;
GN   Name=AP2B1; Synonyms=ADTB2, CLAPB1;
DR   GO; GO:0030276; F:clathrin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP2C_HUMAN              Reviewed;         450 AA.
AC   Q92754; O00685; O00730; Q86V30; Q8IVB6; Q9P1X2;
DE   RecName: Full=Transcription factor AP-2 gamma;
DE            Short=AP2-gamma;
DE   AltName: Full=Activating enhancer-binding protein 2 gamma;
DE   AltName: Full=Transcription factor ERF-1;
GN   Name=TFAP2C;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0060598; P:dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0060750; P:epithelial cell proliferation involved in mammary gland duct elongation; IEA:Ensembl.
DR   GO; GO:0021877; P:forebrain neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0030718; P:germ-line stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0003334; P:keratinocyte development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045682; P:regulation of epidermis development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0048733; P:sebaceous gland development; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   AP2B_HUMAN              Reviewed;         460 AA.
AC   Q92481; Q5JYX6; Q9NQ63; Q9NU99; Q9UJI7; Q9Y214; Q9Y3K3;
DE   RecName: Full=Transcription factor AP-2-beta;
DE            Short=AP2-beta;
DE   AltName: Full=Activating enhancer-binding protein 2-beta;
GN   Name=TFAP2B;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0035909; P:aorta morphogenesis; ISS:UniProtKB.
DR   GO; GO:0055074; P:calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0097275; P:cellular ammonia homeostasis; ISS:UniProtKB.
DR   GO; GO:0097276; P:cellular creatinine homeostasis; ISS:UniProtKB.
DR   GO; GO:0097277; P:cellular urea homeostasis; ISS:UniProtKB.
DR   GO; GO:0072044; P:collecting duct development; ISS:UniProtKB.
DR   GO; GO:0072017; P:distal tubule development; ISS:UniProtKB.
DR   GO; GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEP:UniProtKB.
DR   GO; GO:0035136; P:forelimb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:UniProtKB.
DR   GO; GO:0035137; P:hindlimb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0010960; P:magnesium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0072210; P:metanephric nephron development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0055062; P:phosphate ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035810; P:positive regulation of urine volume; ISS:UniProtKB.
DR   GO; GO:0055075; P:potassium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0030510; P:regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0003091; P:renal water homeostasis; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0010842; P:retina layer formation; IEP:UniProtKB.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0055078; P:sodium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
//
ID   AP2D_HUMAN              Reviewed;         452 AA.
AC   Q7Z6R9; Q8IWX0;
DE   RecName: Full=Transcription factor AP-2-delta;
DE            Short=AP2-delta;
DE   AltName: Full=Activating enhancer-binding protein 2-delta;
DE   AltName: Full=Transcription factor AP-2-beta-like 1;
GN   Name=TFAP2D; Synonyms=TFAP2BL1;
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0061379; P:inferior colliculus development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   AP2E_HUMAN              Reviewed;         442 AA.
AC   Q6VUC0; Q8IW12;
DE   RecName: Full=Transcription factor AP-2-epsilon;
DE            Short=AP2-epsilon;
DE   AltName: Full=Activating enhancer-binding protein 2-epsilon;
GN   Name=TFAP2E;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AP2M1_HUMAN             Reviewed;         435 AA.
AC   Q96CW1; A6NE12; D3DNT1; P20172; P53679;
DE   RecName: Full=AP-2 complex subunit mu;
DE   AltName: Full=AP-2 mu chain;
DE   AltName: Full=Adapter-related protein complex 2 subunit mu;
DE   AltName: Full=Adaptin-mu2;
DE   AltName: Full=Adaptor protein complex AP-2 subunit mu;
DE   AltName: Full=Clathrin assembly protein complex 2 mu medium chain;
DE   AltName: Full=Clathrin coat assembly protein AP50;
DE   AltName: Full=Clathrin coat-associated protein AP50;
DE   AltName: Full=HA2 50 kDa subunit;
DE   AltName: Full=Plasma membrane adaptor AP-2 50 kDa protein;
GN   Name=AP2M1; Synonyms=CLAPM1, KIAA0109;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP2S1_HUMAN             Reviewed;         142 AA.
AC   P53680; B2R4Z4; O75977; Q6PK67;
DE   RecName: Full=AP-2 complex subunit sigma;
DE   AltName: Full=Adapter-related protein complex 2 subunit sigma;
DE   AltName: Full=Adaptor protein complex AP-2 subunit sigma;
DE   AltName: Full=Clathrin assembly protein 2 sigma small chain;
DE   AltName: Full=Clathrin coat assembly protein AP17;
DE   AltName: Full=Clathrin coat-associated protein AP17;
DE   AltName: Full=HA2 17 kDa subunit;
DE   AltName: Full=Plasma membrane adaptor AP-2 17 kDa protein;
DE   AltName: Full=Sigma2-adaptin;
GN   Name=AP2S1; Synonyms=AP17, CLAPS2;
DR   GO; GO:0008565; F:protein transporter activity; NAS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0048268; P:clathrin coat assembly; TAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   AP3B1_HUMAN             Reviewed;        1094 AA.
AC   O00203; E5RJ68; O00580; Q7Z393; Q9HD66;
DE   RecName: Full=AP-3 complex subunit beta-1;
DE   AltName: Full=Adapter-related protein complex 3 subunit beta-1;
DE   AltName: Full=Adaptor protein complex AP-3 subunit beta-1;
DE   AltName: Full=Beta-3A-adaptin;
DE   AltName: Full=Clathrin assembly protein complex 3 beta-1 large chain;
GN   Name=AP3B1; Synonyms=ADTB3A;
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; IEA:Ensembl.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; IEA:Ensembl.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0032438; P:melanosome organization; IMP:UniProtKB.
DR   GO; GO:0051138; P:positive regulation of NK T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006622; P:protein targeting to lysosome; IEA:Ensembl.
//
ID   AP3B2_HUMAN             Reviewed;        1082 AA.
AC   Q13367; A4Z4T7; B7ZKR7; B7ZKS0; O14808; Q52LY8;
DE   RecName: Full=AP-3 complex subunit beta-2;
DE   AltName: Full=Adapter-related protein complex 3 subunit beta-2;
DE   AltName: Full=Adaptor protein complex AP-3 subunit beta-2;
DE   AltName: Full=Beta-3B-adaptin;
DE   AltName: Full=Clathrin assembly protein complex 3 beta-2 large chain;
DE   AltName: Full=Neuron-specific vesicle coat protein beta-NAP;
GN   Name=AP3B2;
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
//
ID   AP3D1_HUMAN             Reviewed;        1153 AA.
AC   O14617; O00202; O75262; Q59HF5; Q96G11; Q9H3C6;
DE   RecName: Full=AP-3 complex subunit delta-1;
DE   AltName: Full=AP-3 complex subunit delta;
DE   AltName: Full=Adapter-related protein complex 3 subunit delta-1;
DE   AltName: Full=Delta-adaptin;
GN   Name=AP3D1; ORFNames=PRO0039;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IEA:Ensembl.
DR   GO; GO:0006726; P:eye pigment biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0051138; P:positive regulation of NK T cell differentiation; IEA:Ensembl.
DR   GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR   GO; GO:0061088; P:regulation of sequestering of zinc ion; IMP:BHF-UCL.
DR   GO; GO:0048499; P:synaptic vesicle membrane organization; IEA:Ensembl.
//
ID   AP3M1_HUMAN             Reviewed;         418 AA.
AC   Q9Y2T2; Q5JQ12; Q9H5L2;
DE   RecName: Full=AP-3 complex subunit mu-1;
DE   AltName: Full=AP-3 adapter complex mu3A subunit;
DE   AltName: Full=Adapter-related protein complex 3 subunit mu-1;
DE   AltName: Full=Mu-adaptin 3A;
DE   AltName: Full=Mu3A-adaptin;
GN   Name=AP3M1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0006622; P:protein targeting to lysosome; TAS:ProtInc.
//
ID   AP3M2_HUMAN             Reviewed;         418 AA.
AC   P53677; B2RCR0; D3DSY2;
DE   RecName: Full=AP-3 complex subunit mu-2;
DE   AltName: Full=Adapter-related protein complex 3 subunit mu-2;
DE   AltName: Full=Clathrin assembly protein assembly protein complex 3 mu-2 medium chain;
DE   AltName: Full=Clathrin coat assembly protein AP47 homolog 2;
DE   AltName: Full=Clathrin coat-associated protein AP47 homolog 2;
DE   AltName: Full=Golgi adaptor AP-1 47 kDa protein homolog 2;
DE   AltName: Full=HA1 47 kDa subunit homolog 2;
DE   AltName: Full=Mu3B-adaptin;
DE   AltName: Full=P47B;
GN   Name=AP3M2;
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   AP3S1_HUMAN             Reviewed;         193 AA.
AC   Q92572; O00647; O00676; O00721; O00727; Q53XL4; Q6ICQ2;
DE   RecName: Full=AP-3 complex subunit sigma-1;
DE   AltName: Full=AP-3 complex subunit sigma-3A;
DE   AltName: Full=Adapter-related protein complex 3 subunit sigma-1;
DE   AltName: Full=Clathrin-associated/assembly/adapter protein, small 3;
DE   AltName: Full=Sigma-3A-adaptin;
DE            Short=Sigma3A-adaptin;
DE   AltName: Full=Sigma-adaptin 3a;
GN   Name=AP3S1; Synonyms=CLAPS3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   AP3S2_HUMAN             Reviewed;         193 AA.
AC   P59780; B2R677; B4DGQ3; O09077; O09149; Q53H83; Q99589;
DE   RecName: Full=AP-3 complex subunit sigma-2;
DE   AltName: Full=AP-3 complex subunit sigma-3B;
DE   AltName: Full=Adapter-related protein complex 3 subunit sigma-2;
DE   AltName: Full=Sigma-3B-adaptin;
DE            Short=Sigma3B-adaptin;
DE   AltName: Full=Sigma-adaptin 3b;
GN   Name=AP3S2;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
//
ID   AP4AT_HUMAN             Reviewed;         525 AA.
AC   Q96N21; Q6ZQU0; Q6ZSQ9;
DE   RecName: Full=AP-4 complex accessory subunit tepsin;
DE   AltName: Full=ENTH domain-containing protein 2;
DE   AltName: Full=Epsin for AP-4;
DE   AltName: Full=Tetra-epsin;
GN   Name=ENTHD2; Synonyms=C17orf56;
//
ID   AP4A_HUMAN              Reviewed;         147 AA.
AC   P50583; D3DRM0; Q5T589;
DE   RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical];
DE            EC=3.6.1.17;
DE   AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase;
DE            Short=Ap4A hydrolase;
DE            Short=Ap4Aase;
DE            Short=Diadenosine tetraphosphatase;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 2;
DE            Short=Nudix motif 2;
GN   Name=NUDT2; Synonyms=APAH1;
DR   GO; GO:0004081; F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity; ISS:UniProtKB.
DR   GO; GO:0008803; F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
//
ID   AP4B1_HUMAN             Reviewed;         739 AA.
AC   Q9Y6B7; Q59EJ4; Q96CL6;
DE   RecName: Full=AP-4 complex subunit beta-1;
DE   AltName: Full=AP-4 adapter complex subunit beta;
DE   AltName: Full=Adapter-related protein complex 4 subunit beta-1;
DE   AltName: Full=Beta subunit of AP-4;
DE   AltName: Full=Beta4-adaptin;
GN   Name=AP4B1;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   AP4M1_HUMAN             Reviewed;         453 AA.
AC   O00189; D6W5U1; Q8WV65; Q9UHK9;
DE   RecName: Full=AP-4 complex subunit mu-1;
DE   AltName: Full=AP-4 adapter complex mu subunit;
DE   AltName: Full=Adapter-related protein complex 4 subunit mu-1;
DE   AltName: Full=Mu subunit of AP-4;
DE   AltName: Full=Mu-adaptin-related protein 2;
DE            Short=mu-ARP2;
DE   AltName: Full=Mu4-adaptin;
DE            Short=mu4;
GN   Name=AP4M1; Synonyms=MUARP2;
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006895; P:Golgi to endosome transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   AP4E1_HUMAN             Reviewed;        1137 AA.
AC   Q9UPM8; A0AVD6; A1L4A9; A6NNX7; H0YKX4; Q68D31; Q9Y588;
DE   RecName: Full=AP-4 complex subunit epsilon-1;
DE   AltName: Full=AP-4 adapter complex subunit epsilon;
DE   AltName: Full=Adapter-related protein complex 4 subunit epsilon-1;
DE   AltName: Full=Epsilon subunit of AP-4;
DE   AltName: Full=Epsilon-adaptin;
GN   Name=AP4E1;
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   AP4S1_HUMAN             Reviewed;         144 AA.
AC   Q9Y587; G3V2N8; Q6IAQ4; Q86U36; Q9BVE7;
DE   RecName: Full=AP-4 complex subunit sigma-1;
DE   AltName: Full=AP-4 adapter complex subunit sigma-1;
DE   AltName: Full=Adapter-related protein complex 4 subunit sigma-1;
DE   AltName: Full=Sigma-1 subunit of AP-4;
DE   AltName: Full=Sigma-4-adaptin;
DE            Short=Sigma4-adaptin;
GN   Name=AP4S1;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
//
ID   AP5M1_HUMAN             Reviewed;         490 AA.
AC   Q9H0R1; O95354; Q6ZMD7; Q96DX3; Q9NVC5;
DE   RecName: Full=AP-5 complex subunit mu-1;
DE   AltName: Full=Adapter-related protein complex 5 subunit mu-1;
DE            Short=Mu5;
DE   AltName: Full=Mu-2-related death-inducing protein;
DE            Short=MuD;
DE   AltName: Full=Putative HIV-1 infection-related protein;
GN   Name=AP5M1; Synonyms=C14orf108, MUDENG;
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   AP5B1_HUMAN             Reviewed;         878 AA.
AC   Q2VPB7; A1L0S6; H6WUK2; Q0D2Q2; Q8N3J7; Q8WYH6;
DE   RecName: Full=AP-5 complex subunit beta-1;
DE   AltName: Full=Adapter-related protein complex 5 beta subunit;
DE            Short=Beta5;
GN   Name=AP5B1; ORFNames=PP1030;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AP5S1_HUMAN             Reviewed;         200 AA.
AC   Q9NUS5; B3KSD0; D3DVY7;
DE   RecName: Full=AP-5 complex subunit sigma-1;
DE   AltName: Full=Adapter-related protein complex 5 sigma subunit;
DE            Short=Sigma5;
GN   Name=AP5S1; Synonyms=C20orf29;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   AP5Z1_HUMAN             Reviewed;         807 AA.
AC   O43299; Q8N3X2; Q96H80;
DE   RecName: Full=AP-5 complex subunit zeta-1;
DE   AltName: Full=Adapter-related protein complex 5 zeta subunit;
DE            Short=Zeta5;
GN   Name=AP5Z1; Synonyms=KIAA0415, SPG48;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   APAF_HUMAN              Reviewed;        1248 AA.
AC   O14727; B2RMX8; O43297; Q7Z438; Q9BXZ6; Q9UBZ5; Q9UGN8; Q9UGN9;
AC   Q9UGP0; Q9UJ58; Q9UJ59; Q9UJ60; Q9UJ61; Q9UJ62; Q9UJ63; Q9UJ64;
AC   Q9UJ65; Q9UJ66; Q9UJ67; Q9UNC9;
DE   RecName: Full=Apoptotic protease-activating factor 1;
DE            Short=APAF-1;
GN   Name=APAF1; Synonyms=KIAA0413;
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0072432; P:response to G1 DNA damage checkpoint signaling; TAS:UniProtKB.
//
ID   APBA1_HUMAN             Reviewed;         837 AA.
AC   Q02410; O14914; O60570; Q5VYR8;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family A member 1;
DE   AltName: Full=Adapter protein X11alpha;
DE   AltName: Full=Neuron-specific X11 protein;
DE   AltName: Full=Neuronal Munc18-1-interacting protein 1;
DE            Short=Mint-1;
GN   Name=APBA1; Synonyms=MINT1, X11;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008088; P:axon cargo transport; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0014051; P:gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0014047; P:glutamate secretion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   APBA2_HUMAN             Reviewed;         749 AA.
AC   Q99767; E9PGI4; O60571; Q5XKC0;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family A member 2;
DE   AltName: Full=Adapter protein X11beta;
DE   AltName: Full=Neuron-specific X11L protein;
DE   AltName: Full=Neuronal Munc18-1-interacting protein 2;
DE            Short=Mint-2;
GN   Name=APBA2; Synonyms=MINT2, X11L;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   APBA3_HUMAN             Reviewed;         575 AA.
AC   O96018; O60483; Q9UPZ2;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family A member 3;
DE   AltName: Full=Adapter protein X11gamma;
DE   AltName: Full=Neuron-specific X11L2 protein;
DE   AltName: Full=Neuronal Munc18-1-interacting protein 3;
DE            Short=Mint-3;
GN   Name=APBA3; Synonyms=MINT3, X11L2;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   APBB1_HUMAN             Reviewed;         710 AA.
AC   O00213; A1E379; A6NH82; A6NL69; B7Z1J5; B7Z1J6; B7Z2Y0; D3DQT2;
AC   Q7Z324; Q96A93; V9GYK0; V9GYT4;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family B member 1;
DE   AltName: Full=Protein Fe65;
GN   Name=APBB1; Synonyms=FE65, RIR;
DR   GO; GO:0001540; F:beta-amyloid binding; ISS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; NAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0050760; P:negative regulation of thymidylate synthase biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   APBB2_HUMAN             Reviewed;         758 AA.
AC   Q92870; B4DSL4; E9PG87; Q8IUI6;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family B member 2;
DE   AltName: Full=Protein Fe65-like 1;
GN   Name=APBB2; Synonyms=FE65L, FE65L1;
DR   GO; GO:0001540; F:beta-amyloid binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
//
ID   APBB3_HUMAN             Reviewed;         486 AA.
AC   O95704; B3KQN9; Q08AG4; Q96Q18; Q9BYD4; Q9NYX6; Q9NYX7; Q9NYX8;
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family B member 3;
DE   AltName: Full=Protein Fe65-like 2;
DE            Short=Fe65L2;
GN   Name=APBB3; Synonyms=FE65L2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   APBP2_HUMAN             Reviewed;         585 AA.
AC   Q92624; A8K862; O95095; Q8WVC9;
DE   RecName: Full=Amyloid protein-binding protein 2;
DE   AltName: Full=Amyloid beta precursor protein-binding protein 2;
DE            Short=APP-BP2;
DE   AltName: Full=Protein interacting with APP tail 1;
GN   Name=APPBP2; Synonyms=KIAA0228, PAT1;
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0046907; P:intracellular transport; IDA:MGI.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
//
ID   APC10_HUMAN             Reviewed;         185 AA.
AC   Q9UM13; D3DNZ7; Q2V500; Q9UG51; Q9Y5R0;
DE   RecName: Full=Anaphase-promoting complex subunit 10;
DE            Short=APC10;
DE   AltName: Full=Cyclosome subunit 10;
GN   Name=ANAPC10; Synonyms=APC10;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0000090; P:mitotic anaphase; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   APC11_HUMAN             Reviewed;          84 AA.
AC   Q9NYG5; A8MTT2; B7ZW64; Q502X9; Q9BW64; Q9P0R2;
DE   RecName: Full=Anaphase-promoting complex subunit 11;
DE            Short=APC11;
DE   AltName: Full=Cyclosome subunit 11;
DE   AltName: Full=Hepatocellular carcinoma-associated RING finger protein;
GN   Name=ANAPC11; ORFNames=HSPC214;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   APC13_HUMAN             Reviewed;          74 AA.
AC   Q9BS18; Q9Y3V0;
DE   RecName: Full=Anaphase-promoting complex subunit 13;
DE            Short=APC13;
DE   AltName: Full=Cyclosome subunit 13;
GN   Name=ANAPC13;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
//
ID   APC15_HUMAN             Reviewed;         121 AA.
AC   P60006; G3V1Q3; Q9CXK2; Q9Y269;
DE   RecName: Full=Anaphase-promoting complex subunit 15;
DE            Short=APC15;
GN   Name=ANAPC15; Synonyms=C11orf51; ORFNames=HSPC020;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0090266; P:regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
//
ID   APC16_HUMAN             Reviewed;         110 AA.
AC   Q96DE5;
DE   RecName: Full=Anaphase-promoting complex subunit 16;
DE            Short=APC16;
DE   AltName: Full=Cyclosome subunit 16;
GN   Name=ANAPC16; Synonyms=C10orf104;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   APC1_HUMAN              Reviewed;        1944 AA.
AC   Q9H1A4; Q2M3H8; Q9BSE6; Q9H8D0;
DE   RecName: Full=Anaphase-promoting complex subunit 1;
DE            Short=APC1;
DE   AltName: Full=Cyclosome subunit 1;
DE   AltName: Full=Mitotic checkpoint regulator;
DE   AltName: Full=Testis-specific gene 24 protein;
GN   Name=ANAPC1; Synonyms=TSG24;
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   APC2_HUMAN              Reviewed;        2303 AA.
AC   O95996; Q05BW4; Q9UBZ1; Q9UEM8; Q9UQJ8; Q9UQJ9; Q9Y632;
DE   RecName: Full=Adenomatous polyposis coli protein 2;
DE   AltName: Full=Adenomatous polyposis coli protein-like;
DE            Short=APC-like;
GN   Name=APC2; Synonyms=APCL;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   APC4_HUMAN              Reviewed;         808 AA.
AC   Q9UJX5; A8K8H1; Q6PCC6; Q9NSH6;
DE   RecName: Full=Anaphase-promoting complex subunit 4;
DE            Short=APC4;
DE   AltName: Full=Cyclosome subunit 4;
GN   Name=ANAPC4; Synonyms=APC4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000090; P:mitotic anaphase; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   APC5_HUMAN              Reviewed;         755 AA.
AC   Q9UJX4; E9PFB2; Q8N4H7; Q9BQD4;
DE   RecName: Full=Anaphase-promoting complex subunit 5;
DE            Short=APC5;
DE   AltName: Full=Cyclosome subunit 5;
GN   Name=ANAPC5; Synonyms=APC5;
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000090; P:mitotic anaphase; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   APC7_HUMAN              Reviewed;         599 AA.
AC   Q9UJX3; Q96AC4; Q96GF4; Q9BU24; Q9NT16;
DE   RecName: Full=Anaphase-promoting complex subunit 7;
DE            Short=APC7;
DE   AltName: Full=Cyclosome subunit 7;
GN   Name=ANAPC7; Synonyms=APC7;
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   APCD1_HUMAN             Reviewed;         514 AA.
AC   Q8J025; B4DUQ0; B4DZT0; Q71M25;
DE   RecName: Full=Protein APCDD1;
DE   AltName: Full=Adenomatosis polyposis coli down-regulated 1 protein;
DE   Flags: Precursor;
GN   Name=APCDD1; Synonyms=DRAPC1; ORFNames=FP7019;
DR   GO; GO:0017147; F:Wnt-protein binding; IDA:UniProtKB.
DR   GO; GO:0043615; P:astrocyte cell migration; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IMP:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   APCDL_HUMAN             Reviewed;         501 AA.
AC   Q8NCL9;
DE   RecName: Full=Protein APCDD1-like;
DE   AltName: Full=Adenomatosis polyposis coli down-regulated 1 protein-like;
DE   Flags: Precursor;
GN   Name=APCDD1L;
//
ID   APC_HUMAN               Reviewed;        2843 AA.
AC   P25054; D3DT03; Q15162; Q15163; Q93042;
DE   RecName: Full=Adenomatous polyposis coli protein;
DE            Short=Protein APC;
DE   AltName: Full=Deleted in polyposis 2.5;
GN   Name=APC; Synonyms=DP2.5;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019887; F:protein kinase regulator activity; IDA:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0009798; P:axis specification; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0044336; P:canonical Wnt signaling pathway involved in negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0044337; P:canonical Wnt signaling pathway involved in positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:MGI.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:MGI.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IGI:MGI.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0042483; P:negative regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:MGI.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IMP:MGI.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; NAS:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
DR   GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:Ensembl.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; NAS:UniProtKB.
//
ID   APEL_HUMAN              Reviewed;          77 AA.
AC   Q9ULZ1; Q4VY08; Q8WU89;
DE   RecName: Full=Apelin;
DE   AltName: Full=APJ endogenous ligand;
DE   Contains:
DE     RecName: Full=Apelin-36;
DE   Contains:
DE     RecName: Full=Apelin-31;
DE   Contains:
DE     RecName: Full=Apelin-28;
DE   Contains:
DE     RecName: Full=Apelin-13;
DE   Flags: Precursor;
GN   Name=APLN; Synonyms=APEL;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0042756; P:drinking behavior; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007595; P:lactation; TAS:ProtInc.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045906; P:negative regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051461; P:positive regulation of corticotropin secretion; IEA:Ensembl.
DR   GO; GO:0051466; P:positive regulation of corticotropin-releasing hormone secretion; IEA:Ensembl.
DR   GO; GO:0031652; P:positive regulation of heat generation; IEA:Ensembl.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0043576; P:regulation of respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   APEX1_HUMAN             Reviewed;         318 AA.
AC   P27695; Q969L5; Q99775;
DE   RecName: Full=DNA-(apurinic or apyrimidinic site) lyase;
DE            EC=3.1.-.-;
DE            EC=4.2.99.18;
DE   AltName: Full=APEX nuclease;
DE            Short=APEN;
DE   AltName: Full=Apurinic-apyrimidinic endonuclease 1;
DE            Short=AP endonuclease 1;
DE            Short=APE-1;
DE   AltName: Full=REF-1;
DE   AltName: Full=Redox factor-1;
DE   Contains:
DE     RecName: Full=DNA-(apurinic or apyrimidinic site) lyase, mitochondrial;
GN   Name=APEX1; Synonyms=APE, APE1, APEX, APX, HAP1, REF1;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0004519; F:endonuclease activity; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0004528; F:phosphodiesterase I activity; TAS:UniProtKB.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; TAS:UniProtKB.
DR   GO; GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0004844; F:uracil DNA N-glycosylase activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0043488; P:regulation of mRNA stability; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   APEX2_HUMAN             Reviewed;         518 AA.
AC   Q9UBZ4; Q9Y5X7;
DE   RecName: Full=DNA-(apurinic or apyrimidinic site) lyase 2;
DE            EC=3.1.-.-;
DE            EC=4.2.99.18;
DE   AltName: Full=AP endonuclease XTH2;
DE   AltName: Full=APEX nuclease 2;
DE   AltName: Full=APEX nuclease-like 2;
DE   AltName: Full=Apurinic-apyrimidinic endonuclease 2;
DE            Short=AP endonuclease 2;
GN   Name=APEX2; Synonyms=APE2, APEXL2, XTH2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
//
ID   APH1A_HUMAN             Reviewed;         265 AA.
AC   Q96BI3; B4DQK0; Q5TB22; Q5TB23; Q969R6; Q9BVG0; Q9Y386;
DE   RecName: Full=Gamma-secretase subunit APH-1A;
DE            Short=APH-1a;
DE   AltName: Full=Aph-1alpha;
DE   AltName: Full=Presenilin-stabilization factor;
GN   Name=APH1A; Synonyms=PSF; ORFNames=CGI-78, UNQ579/PRO1141;
DR   GO; GO:0004175; F:endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:HGNC.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; IMP:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; IMP:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:HGNC.
DR   GO; GO:0016485; P:protein processing; IDA:HGNC.
//
ID   APH1B_HUMAN             Reviewed;         257 AA.
AC   Q8WW43; A8K589; Q564N3; Q6UWQ1; Q9H0S0;
DE   RecName: Full=Gamma-secretase subunit APH-1B;
DE            Short=APH-1b;
DE   AltName: Full=Aph-1beta;
DE   AltName: Full=Presenilin-stabilization factor-like;
GN   Name=APH1B; Synonyms=PSFL; ORFNames=UNQ688/PRO1328;
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IEA:InterPro.
DR   GO; GO:0016485; P:protein processing; IDA:MGI.
//
ID   API5_HUMAN              Reviewed;         524 AA.
AC   Q9BZZ5; B4DGR0; B4DRJ2; D3DR21; O15441; Q9Y4J7;
DE   RecName: Full=Apoptosis inhibitor 5;
DE            Short=API-5;
DE   AltName: Full=Antiapoptosis clone 11 protein;
DE            Short=AAC-11;
DE   AltName: Full=Cell migration-inducing gene 8 protein;
DE   AltName: Full=Fibroblast growth factor 2-interacting factor;
DE            Short=FIF;
DE   AltName: Full=Protein XAGL;
GN   Name=API5; ORFNames=MIG8;
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IEA:Ensembl.
//
ID   APJ_HUMAN               Reviewed;         380 AA.
AC   P35414;
DE   RecName: Full=Apelin receptor;
DE   AltName: Full=Angiotensin receptor-like 1;
DE   AltName: Full=G-protein coupled receptor APJ;
DE   AltName: Full=G-protein coupled receptor HG11;
GN   Name=APLNR; Synonyms=AGTRL1, APJ;
DR   GuidetoPHARMACOLOGY; 36; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007369; P:gastrulation; IEA:UniProtKB-KW.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0050878; P:regulation of body fluid levels; IEA:Ensembl.
//
ID   APLD1_HUMAN             Reviewed;         279 AA.
AC   Q96LR9; Q8IVR2; Q9H0I5;
DE   RecName: Full=Apolipoprotein L domain-containing protein 1;
DE   AltName: Full=Vascular early response gene protein;
GN   Name=APOLD1; Synonyms=VERGE;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0042118; P:endothelial cell activation; IEA:Ensembl.
DR   GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   GO; GO:0045601; P:regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   APLF_HUMAN              Reviewed;         511 AA.
AC   Q8IW19; A8K476; Q53P47; Q53PB9; Q53QU0;
DE   RecName: Full=Aprataxin and PNK-like factor;
DE            EC=4.2.99.18;
DE   AltName: Full=Apurinic-apyrimidinic endonuclease APLF;
DE   AltName: Full=PNK and APTX-like FHA domain-containing protein;
DE   AltName: Full=XRCC1-interacting protein 1;
GN   Name=APLF; Synonyms=C2orf13, PALF, XIP1;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0051106; P:positive regulation of DNA ligation; IGI:MGI.
DR   GO; GO:0000012; P:single strand break repair; IMP:UniProtKB.
//
ID   APLP1_HUMAN             Reviewed;         650 AA.
AC   P51693; O00113; Q96A92;
DE   RecName: Full=Amyloid-like protein 1;
DE            Short=APLP;
DE            Short=APLP-1;
DE   Contains:
DE     RecName: Full=C30;
DE   Flags: Precursor;
GN   Name=APLP1;
DR   GO; GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031695; F:alpha-2B adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031696; F:alpha-2C adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0071874; P:cellular response to norepinephrine stimulus; IDA:BHF-UCL.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:Ensembl.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
//
ID   APLP2_HUMAN             Reviewed;         763 AA.
AC   Q06481; B3KXX9; H7BXI4; Q13861; Q14594; Q14662; Q71U10; Q7M4L3;
AC   Q9BT36;
DE   RecName: Full=Amyloid-like protein 2;
DE            Short=APLP-2;
DE   AltName: Full=APPH;
DE   AltName: Full=Amyloid protein homolog;
DE   AltName: Full=CDEI box-binding protein;
DE            Short=CDEBP;
DE   Flags: Precursor;
GN   Name=APLP2; Synonyms=APPL2;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007617; P:mating behavior; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; IEA:Ensembl.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
//
ID   APMAP_HUMAN             Reviewed;         416 AA.
AC   Q9HDC9; A8K514; B4DXG1; Q6UVZ8; Q9GZS8; Q9NUB2;
DE   RecName: Full=Adipocyte plasma membrane-associated protein;
DE   AltName: Full=Protein BSCv;
GN   Name=APMAP; Synonyms=C20orf3; ORFNames=UNQ1869/PRO4305;
DR   GO; GO:0004064; F:arylesterase activity; IDA:UniProtKB.
DR   GO; GO:0016844; F:strictosidine synthase activity; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
//
ID   APOA1_HUMAN             Reviewed;         267 AA.
AC   P02647; A8K866; Q6LDN9; Q6Q785; Q9UCS8; Q9UCT8;
DE   RecName: Full=Apolipoprotein A-I;
DE            Short=Apo-AI;
DE            Short=ApoA-I;
DE   AltName: Full=Apolipoprotein A1;
DE   Contains:
DE     RecName: Full=Proapolipoprotein A-I;
DE              Short=ProapoA-I;
DE   Contains:
DE     RecName: Full=Truncated apolipoprotein A-I;
DE     AltName: Full=Apolipoprotein A-I(1-242);
DE   Flags: Precursor;
GN   Name=APOA1;
DR   GO; GO:0034191; F:apolipoprotein A-I receptor binding; IPI:BHF-UCL.
DR   GO; GO:0034190; F:apolipoprotein receptor binding; IPI:BHF-UCL.
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:BHF-UCL.
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0017127; F:cholesterol transporter activity; IMP:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0070653; F:high-density lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0055102; F:lipase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0060228; F:phosphatidylcholine-sterol O-acyltransferase activator activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0005548; F:phospholipid transporter activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0070508; P:cholesterol import; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IMP:BHF-UCL.
DR   GO; GO:0030301; P:cholesterol transport; IDA:MGI.
DR   GO; GO:0001935; P:endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008211; P:glucocorticoid metabolic process; IEA:Ensembl.
DR   GO; GO:0034380; P:high-density lipoprotein particle assembly; IDA:BHF-UCL.
DR   GO; GO:0034384; P:high-density lipoprotein particle clearance; IC:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IC:BHF-UCL.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0060354; P:negative regulation of cell adhesion molecule production; IDA:BHF-UCL.
DR   GO; GO:0002740; P:negative regulation of cytokine secretion involved in immune response; IDA:BHF-UCL.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0050713; P:negative regulation of interleukin-1 beta secretion; IDA:BHF-UCL.
DR   GO; GO:0060192; P:negative regulation of lipase activity; IEA:Ensembl.
DR   GO; GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010903; P:negative regulation of very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0018206; P:peptidyl-methionine modification; IDA:UniProtKB.
DR   GO; GO:0014012; P:peripheral nervous system axon regeneration; IEA:Ensembl.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; IDA:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0051345; P:positive regulation of hydrolase activity; IDA:BHF-UCL.
DR   GO; GO:0051347; P:positive regulation of transferase activity; IEA:Ensembl.
DR   GO; GO:0018158; P:protein oxidation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0032489; P:regulation of Cdc42 protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0030300; P:regulation of intestinal cholesterol absorption; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0043691; P:reverse cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; IDA:BHF-UCL.
//
ID   APOA2_HUMAN             Reviewed;         100 AA.
AC   P02652; B2R524;
DE   RecName: Full=Apolipoprotein A-II;
DE            Short=Apo-AII;
DE            Short=ApoA-II;
DE   AltName: Full=Apolipoprotein A2;
DE   Contains:
DE     RecName: Full=Proapolipoprotein A-II;
DE              Short=ProapoA-II;
DE   Contains:
DE     RecName: Full=Truncated apolipoprotein A-II;
DE     AltName: Full=Apolipoprotein A-II(1-76);
DE   Flags: Precursor;
GN   Name=APOA2;
DR   GO; GO:0034190; F:apolipoprotein receptor binding; IPI:BHF-UCL.
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0017127; F:cholesterol transporter activity; IEA:Ensembl.
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0070653; F:high-density lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:0055102; F:lipase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IDA:BHF-UCL.
DR   GO; GO:0005319; F:lipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:BHF-UCL.
DR   GO; GO:0060228; F:phosphatidylcholine-sterol O-acyltransferase activator activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0046340; P:diacylglycerol catabolic process; IDA:BHF-UCL.
DR   GO; GO:0034380; P:high-density lipoprotein particle assembly; IDA:BHF-UCL.
DR   GO; GO:0034384; P:high-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0060621; P:negative regulation of cholesterol import; IDA:BHF-UCL.
DR   GO; GO:0032375; P:negative regulation of cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0060695; P:negative regulation of cholesterol transporter activity; IDA:BHF-UCL.
DR   GO; GO:0002740; P:negative regulation of cytokine secretion involved in immune response; IDA:BHF-UCL.
DR   GO; GO:0060192; P:negative regulation of lipase activity; IDA:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010903; P:negative regulation of very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0018206; P:peptidyl-methionine modification; IDA:UniProtKB.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0009395; P:phospholipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050996; P:positive regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; IDA:BHF-UCL.
DR   GO; GO:0018158; P:protein oxidation; IDA:UniProtKB.
DR   GO; GO:0030300; P:regulation of intestinal cholesterol absorption; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IDA:BHF-UCL.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0043691; P:reverse cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; TAS:BHF-UCL.
DR   GO; GO:0034370; P:triglyceride-rich lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   APOA_HUMAN              Reviewed;        4548 AA.
AC   P08519; Q5VTD7; Q9UD88;
DE   RecName: Full=Apolipoprotein(a);
DE            Short=Apo(a);
DE            Short=Lp(a);
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=LPA;
DR   GO; GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0001968; F:fibronectin binding; IPI:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   APOA5_HUMAN             Reviewed;         366 AA.
AC   Q6Q788; B0YIV9; Q3MIK6; Q6UWK9; Q9UBJ3;
DE   RecName: Full=Apolipoprotein A-V;
DE            Short=Apo-AV;
DE            Short=ApoA-V;
DE   AltName: Full=Apolipoprotein A5;
DE   AltName: Full=Regeneration-associated protein 3;
DE   Flags: Precursor;
GN   Name=APOA5; Synonyms=RAP3; ORFNames=UNQ411/PRO773;
DR   GO; GO:0008047; F:enzyme activator activity; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0060229; F:lipase activator activity; IMP:BHF-UCL.
DR   GO; GO:0035473; F:lipase binding; IPI:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0060230; F:lipoprotein lipase activator activity; IDA:BHF-UCL.
DR   GO; GO:0070325; F:lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0055090; P:acylglycerol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IDA:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0050996; P:positive regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:BHF-UCL.
DR   GO; GO:0010898; P:positive regulation of triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010902; P:positive regulation of very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042246; P:tissue regeneration; IEP:UniProtKB.
DR   GO; GO:0019433; P:triglyceride catabolic process; IMP:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IDA:BHF-UCL.
DR   GO; GO:0034370; P:triglyceride-rich lipoprotein particle remodeling; IEA:Ensembl.
//
ID   APOA4_HUMAN             Reviewed;         396 AA.
AC   P06727; A8MSL6; Q14CW8; Q6Q787;
DE   RecName: Full=Apolipoprotein A-IV;
DE            Short=Apo-AIV;
DE            Short=ApoA-IV;
DE   AltName: Full=Apolipoprotein A4;
DE   Flags: Precursor;
GN   Name=APOA4;
DR   GO; GO:0016209; F:antioxidant activity; IDA:HGNC.
DR   GO; GO:0017127; F:cholesterol transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005507; F:copper ion binding; IDA:HGNC.
DR   GO; GO:0008289; F:lipid binding; IMP:BHF-UCL.
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:BHF-UCL.
DR   GO; GO:0060228; F:phosphatidylcholine-sterol O-acyltransferase activator activity; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0034378; P:chylomicron assembly; TAS:BHF-UCL.
DR   GO; GO:0034371; P:chylomicron remodeling; IC:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IC:BHF-UCL.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:HGNC.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:BHF-UCL.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IDA:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0044240; P:multicellular organismal lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0034445; P:negative regulation of plasma lipoprotein particle oxidation; IDA:BHF-UCL.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IDA:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0010898; P:positive regulation of triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0065005; P:protein-lipid complex assembly; IMP:BHF-UCL.
DR   GO; GO:0032374; P:regulation of cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0030300; P:regulation of intestinal cholesterol absorption; IEA:Ensembl.
DR   GO; GO:0019430; P:removal of superoxide radicals; IDA:HGNC.
DR   GO; GO:0006982; P:response to lipid hydroperoxide; IDA:HGNC.
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0043691; P:reverse cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
//
ID   APOBR_HUMAN             Reviewed;        1088 AA.
AC   Q0VD83; H3BU97; Q0VD81; Q8NC15; Q9NPJ9;
DE   RecName: Full=Apolipoprotein B receptor;
DE   AltName: Full=Apolipoprotein B-100 receptor;
DE   AltName: Full=Apolipoprotein B-48 receptor;
DE            Short=Apolipoprotein B48 receptor;
DE            Short=apoB-48R;
GN   Name=APOBR; Synonyms=APOB48R;
DR   GO; GO:0030229; F:very-low-density lipoprotein particle receptor activity; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   APOB_HUMAN              Reviewed;        4563 AA.
AC   P04114; O00502; P78479; P78480; P78481; Q13779; Q13785; Q13786;
AC   Q13787; Q13788; Q4ZG63; Q53QC8; Q7Z600; Q9UMN0;
DE   RecName: Full=Apolipoprotein B-100;
DE            Short=Apo B-100;
DE   Contains:
DE     RecName: Full=Apolipoprotein B-48;
DE              Short=Apo B-48;
DE   Flags: Precursor;
GN   Name=APOB;
DR   GO; GO:0017127; F:cholesterol transporter activity; IMP:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0035473; F:lipase binding; IPI:BHF-UCL.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IMP:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071379; P:cellular response to prostaglandin stimulus; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IMP:BHF-UCL.
DR   GO; GO:0030301; P:cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042159; P:lipoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; IDA:BHF-UCL.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IDA:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:Reactome.
DR   GO; GO:0045540; P:regulation of cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010269; P:response to selenium ion; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0019433; P:triglyceride catabolic process; IEA:Ensembl.
DR   GO; GO:0006642; P:triglyceride mobilization; IEA:Ensembl.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; IC:BHF-UCL.
//
ID   APOC1_HUMAN             Reviewed;          83 AA.
AC   P02654; B2R526; Q6IB97;
DE   RecName: Full=Apolipoprotein C-I;
DE   AltName: Full=Apolipoprotein C1;
DE   Contains:
DE     RecName: Full=Truncated apolipoprotein C-I;
DE   Flags: Precursor;
GN   Name=APOC1;
DR   GO; GO:0005504; F:fatty acid binding; IDA:BHF-UCL.
DR   GO; GO:0055102; F:lipase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0031210; F:phosphatidylcholine binding; TAS:BHF-UCL.
DR   GO; GO:0060228; F:phosphatidylcholine-sterol O-acyltransferase activator activity; TAS:BHF-UCL.
DR   GO; GO:0004859; F:phospholipase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0034382; P:chylomicron remnant clearance; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; TAS:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   GO; GO:0032375; P:negative regulation of cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0045833; P:negative regulation of lipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051005; P:negative regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0010900; P:negative regulation of phosphatidylcholine catabolic process; IDA:BHF-UCL.
DR   GO; GO:0048261; P:negative regulation of receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0010916; P:negative regulation of very-low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0034369; P:plasma lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; TAS:BHF-UCL.
DR   GO; GO:0032374; P:regulation of cholesterol transport; IC:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; TAS:BHF-UCL.
DR   GO; GO:0034447; P:very-low-density lipoprotein particle clearance; IGI:BHF-UCL.
//
ID   APOC2_HUMAN             Reviewed;         101 AA.
AC   P02655; C0JYY4; Q9BS39; Q9UDE3; Q9UNK3;
DE   RecName: Full=Apolipoprotein C-II;
DE            Short=Apo-CII;
DE            Short=ApoC-II;
DE   AltName: Full=Apolipoprotein C2;
DE   Flags: Precursor;
GN   Name=APOC2; Synonyms=APC2;
DR   GO; GO:0055102; F:lipase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IDA:BHF-UCL.
DR   GO; GO:0060230; F:lipoprotein lipase activator activity; IDA:BHF-UCL.
DR   GO; GO:0016004; F:phospholipase activator activity; IDA:BHF-UCL.
DR   GO; GO:0043274; F:phospholipase binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IMP:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IC:BHF-UCL.
DR   GO; GO:0034382; P:chylomicron remnant clearance; IDA:BHF-UCL.
DR   GO; GO:0034371; P:chylomicron remodeling; IC:BHF-UCL.
DR   GO; GO:0034384; P:high-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0032375; P:negative regulation of cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0045833; P:negative regulation of lipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0048261; P:negative regulation of receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0010916; P:negative regulation of very-low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0010518; P:positive regulation of phospholipase activity; IDA:BHF-UCL.
DR   GO; GO:0060697; P:positive regulation of phospholipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010898; P:positive regulation of triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010902; P:positive regulation of very-low-density lipoprotein particle remodeling; IC:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0043691; P:reverse cholesterol transport; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:BHF-UCL.
DR   GO; GO:0034370; P:triglyceride-rich lipoprotein particle remodeling; TAS:BHF-UCL.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; TAS:BHF-UCL.
//
ID   APOC3_HUMAN             Reviewed;          99 AA.
AC   P02656; Q08E83; Q6Q786;
DE   RecName: Full=Apolipoprotein C-III;
DE            Short=Apo-CIII;
DE            Short=ApoC-III;
DE   AltName: Full=Apolipoprotein C3;
DE   Flags: Precursor;
GN   Name=APOC3;
DR   GO; GO:0015485; F:cholesterol binding; IC:BHF-UCL.
DR   GO; GO:0030234; F:enzyme regulator activity; IDA:BHF-UCL.
DR   GO; GO:0070653; F:high-density lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:0055102; F:lipase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0034382; P:chylomicron remnant clearance; IDA:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0060621; P:negative regulation of cholesterol import; IMP:BHF-UCL.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010987; P:negative regulation of high-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0045833; P:negative regulation of lipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051005; P:negative regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0048261; P:negative regulation of receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0010897; P:negative regulation of triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010916; P:negative regulation of very-low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0010903; P:negative regulation of very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0032489; P:regulation of Cdc42 protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0043691; P:reverse cholesterol transport; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IMP:HGNC.
DR   GO; GO:0006642; P:triglyceride mobilization; IEA:Ensembl.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; TAS:BHF-UCL.
//
ID   APOC4_HUMAN             Reviewed;         127 AA.
AC   P55056; B3KWY6; Q53YY8;
DE   RecName: Full=Apolipoprotein C-IV;
DE            Short=Apo-CIV;
DE            Short=ApoC-IV;
DE   AltName: Full=Apolipoprotein C4;
DE   Flags: Precursor;
GN   Name=APOC4;
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; IMP:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:BHF-UCL.
//
ID   APOD_HUMAN              Reviewed;         189 AA.
AC   P05090; B2R579; D3DNW6; Q6IBG6;
DE   RecName: Full=Apolipoprotein D;
DE            Short=Apo-D;
DE            Short=ApoD;
DE   Flags: Precursor;
GN   Name=APOD;
DR   GO; GO:0015485; F:cholesterol binding; IDA:UniProtKB.
DR   GO; GO:0005319; F:lipid transporter activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IDA:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; IDA:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; NAS:GOC.
DR   GO; GO:1900016; P:negative regulation of cytokine production involved in inflammatory response; IDA:UniProtKB.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0060588; P:negative regulation of lipoprotein lipid oxidation; IDA:UniProtKB.
DR   GO; GO:0071638; P:negative regulation of monocyte chemotactic protein-1 production; IDA:UniProtKB.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000098; P:negative regulation of smooth muscle cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:2000405; P:negative regulation of T cell migration; IDA:UniProtKB.
DR   GO; GO:0014012; P:peripheral nervous system axon regeneration; ISS:UniProtKB.
DR   GO; GO:0048678; P:response to axon injury; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; ISS:UniProtKB.
DR   GO; GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0042246; P:tissue regeneration; ISS:UniProtKB.
//
ID   APOE_HUMAN              Reviewed;         317 AA.
AC   P02649; B2RC15; C0JYY5; Q9P2S4;
DE   RecName: Full=Apolipoprotein E;
DE            Short=Apo-E;
DE   Flags: Precursor;
GN   Name=APOE;
DR   GO; GO:0016209; F:antioxidant activity; IDA:BHF-UCL.
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:UniProtKB.
DR   GO; GO:0017127; F:cholesterol transporter activity; IEA:Ensembl.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0046848; F:hydroxyapatite binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IDA:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005319; F:lipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0071813; F:lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0005324; F:long-chain fatty acid transporter activity; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:BHF-UCL.
DR   GO; GO:0046911; F:metal chelating activity; IDA:BHF-UCL.
DR   GO; GO:0060228; F:phosphatidylcholine-sterol O-acyltransferase activator activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0048156; F:tau protein binding; IPI:BHF-UCL.
DR   GO; GO:0070326; F:very-low-density lipoprotein particle receptor binding; IDA:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071397; P:cellular response to cholesterol; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0019934; P:cGMP-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0006707; P:cholesterol catabolic process; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0034382; P:chylomicron remnant clearance; IMP:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0097062; P:dendritic spine maintenance; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0055089; P:fatty acid homeostasis; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0097435; P:fibril organization; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0034380; P:high-density lipoprotein particle assembly; IDA:BHF-UCL.
DR   GO; GO:0034384; P:high-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IGI:BHF-UCL.
DR   GO; GO:0046907; P:intracellular transport; TAS:UniProtKB.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042159; P:lipoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0015909; P:long-chain fatty acid transport; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IEA:Ensembl.
DR   GO; GO:0051651; P:maintenance of location in cell; IEA:Ensembl.
DR   GO; GO:0097114; P:N-methyl-D-aspartate receptor clustering; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:1902430; P:negative regulation of beta-amyloid formation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0045541; P:negative regulation of cholesterol biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0061000; P:negative regulation of dendritic spine development; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IDA:BHF-UCL.
DR   GO; GO:1901627; P:negative regulation of postsynaptic membrane organization; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:1901630; P:negative regulation of presynaptic membrane organization; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IDA:BHF-UCL.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0014012; P:peripheral nervous system axon regeneration; IEA:Ensembl.
DR   GO; GO:0033700; P:phospholipid efflux; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:1902004; P:positive regulation of beta-amyloid formation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0010873; P:positive regulation of cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032805; P:positive regulation of low-density lipoprotein particle receptor catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:1901216; P:positive regulation of neuron death; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IDA:BHF-UCL.
DR   GO; GO:0017038; P:protein import; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0030516; P:regulation of axon extension; TAS:UniProtKB.
DR   GO; GO:1900221; P:regulation of beta-amyloid clearance; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032489; P:regulation of Cdc42 protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:1901214; P:regulation of neuron death; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; TAS:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0000302; P:response to reactive oxygen species; NAS:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0043691; P:reverse cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; TAS:UniProtKB.
DR   GO; GO:0006641; P:triglyceride metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
DR   GO; GO:0034447; P:very-low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
//
ID   APOF_HUMAN              Reviewed;         326 AA.
AC   Q13790; Q8TC13;
DE   RecName: Full=Apolipoprotein F;
DE            Short=Apo-F;
DE   AltName: Full=Lipid transfer inhibitor protein;
DE            Short=LTIP;
DE   Flags: Precursor;
GN   Name=APOF;
DR   GO; GO:0015485; F:cholesterol binding; TAS:ProtInc.
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0033344; P:cholesterol efflux; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; TAS:ProtInc.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   APOH_HUMAN              Reviewed;         345 AA.
AC   P02749; B2R9M3; Q9UCN7;
DE   RecName: Full=Beta-2-glycoprotein 1;
DE   AltName: Full=APC inhibitor;
DE   AltName: Full=Activated protein C-binding protein;
DE   AltName: Full=Anticardiolipin cofactor;
DE   AltName: Full=Apolipoprotein H;
DE            Short=Apo-H;
DE   AltName: Full=Beta-2-glycoprotein I;
DE            Short=B2GPI;
DE            Short=Beta(2)GPI;
DE   Flags: Precursor;
GN   Name=APOH; Synonyms=B2G1;
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IDA:BHF-UCL.
DR   GO; GO:0060230; F:lipoprotein lipase activator activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; IDA:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0033033; P:negative regulation of myeloid cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0034392; P:negative regulation of smooth muscle cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0031639; P:plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; TAS:BHF-UCL.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0051917; P:regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IDA:BHF-UCL.
DR   GO; GO:0034197; P:triglyceride transport; ISS:BHF-UCL.
//
ID   APOL1_HUMAN             Reviewed;         398 AA.
AC   O14791; A5PLQ4; B4DU12; E9PF24; O60804; Q5R3P7; Q5R3P8; Q96AB8;
AC   Q96PM4; Q9BQ03;
DE   RecName: Full=Apolipoprotein L1;
DE   AltName: Full=Apolipoprotein L;
DE            Short=Apo-L;
DE            Short=ApoL;
DE   AltName: Full=Apolipoprotein L-I;
DE            Short=ApoL-I;
DE   Flags: Precursor;
GN   Name=APOL1; Synonyms=APOL;
DR   GO; GO:0005254; F:chloride channel activity; IDA:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IDA:BHF-UCL.
DR   GO; GO:0031640; P:killing of cells of other organism; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
//
ID   APOL2_HUMAN             Reviewed;         337 AA.
AC   Q9BQE5; B0QYK7; O95915; Q59GW9; Q5TH96; Q969T6; Q9BT28; Q9UGT1;
AC   Q9UH10;
DE   RecName: Full=Apolipoprotein L2;
DE   AltName: Full=Apolipoprotein L-II;
DE            Short=ApoL-II;
GN   Name=APOL2;
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; NAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; NAS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; NAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; NAS:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; NAS:UniProtKB.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
//
ID   APOL3_HUMAN             Reviewed;         402 AA.
AC   O95236; B1AHI4; B1AHI5; Q5U5N4; Q9BQ82; Q9BQA3;
DE   RecName: Full=Apolipoprotein L3;
DE   AltName: Full=Apolipoprotein L-III;
DE            Short=ApoL-III;
DE   AltName: Full=TNF-inducible protein CG12-1;
DE            Short=CG12_1;
GN   Name=APOL3;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   APOL4_HUMAN             Reviewed;         351 AA.
AC   Q9BPW4; Q9BQ37; Q9BXQ8;
DE   RecName: Full=Apolipoprotein L4;
DE   AltName: Full=Apolipoprotein L-IV;
DE            Short=ApoL-IV;
DE   Flags: Precursor;
GN   Name=APOL4;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
//
ID   APOL5_HUMAN             Reviewed;         433 AA.
AC   Q9BWW9; Q5TFL9; Q9UGW5;
DE   RecName: Full=Apolipoprotein L5;
DE   AltName: Full=Apolipoprotein L-V;
DE            Short=ApoL-V;
GN   Name=APOL5;
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; NAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
//
ID   APOL6_HUMAN             Reviewed;         343 AA.
AC   Q9BWW8; Q5R3S1; Q658J1; Q8IXX6; Q9UGG1;
DE   RecName: Full=Apolipoprotein L6;
DE   AltName: Full=Apolipoprotein L-VI;
DE            Short=ApoL-VI;
GN   Name=APOL6; ORFNames=UNQ3095/PRO21341;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
//
ID   APOM_HUMAN              Reviewed;         188 AA.
AC   O95445; B0UX98; Q5SRP4; Q9P046; Q9UMP6;
DE   RecName: Full=Apolipoprotein M;
DE            Short=Apo-M;
DE            Short=ApoM;
DE   AltName: Full=Protein G3a;
GN   Name=APOM; Synonyms=G3A, NG20; ORFNames=HSPC336;
DR   GO; GO:0016209; F:antioxidant activity; IDA:BHF-UCL.
DR   GO; GO:0005319; F:lipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IC:BHF-UCL.
DR   GO; GO:0034380; P:high-density lipoprotein particle assembly; ISS:BHF-UCL.
DR   GO; GO:0034384; P:high-density lipoprotein particle clearance; ISS:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0034445; P:negative regulation of plasma lipoprotein particle oxidation; IDA:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0043691; P:reverse cholesterol transport; ISS:BHF-UCL.
//
ID   APOOL_HUMAN             Reviewed;         268 AA.
AC   Q6UXV4; Q3KNU7; Q5H9D1;
DE   RecName: Full=Apolipoprotein O-like;
DE   AltName: Full=Protein FAM121A;
DE   Flags: Precursor;
GN   Name=APOOL; Synonyms=CXorf33, FAM121A; ORFNames=UNQ8193/PRO23204;
//
ID   APOO_HUMAN              Reviewed;         198 AA.
AC   Q9BUR5; B2R4K9; Q9H3J9;
DE   RecName: Full=Apolipoprotein O;
DE   AltName: Full=Protein FAM121B;
DE   Flags: Precursor;
GN   Name=APOO; Synonyms=FAM121B; ORFNames=My025, UNQ1866/PRO4302;
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   APOP1_HUMAN             Reviewed;         206 AA.
AC   Q96IL0; Q53G28;
DE   RecName: Full=Apoptogenic protein 1, mitochondrial;
DE            Short=APOP-1;
DE   Flags: Precursor;
GN   Name=APOPT1; Synonyms=APOP1, C14orf153;
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
//
ID   APRG1_HUMAN             Reviewed;         170 AA.
AC   Q8IVJ8; B7ZMA0; Q8IVJ5; Q8IVJ9;
DE   RecName: Full=AP20 region protein 1;
GN   Name=APRG1; Synonyms=C3orf35;
//
ID   APRIO_HUMAN             Reviewed;          73 AA.
AC   F7VJQ1;
DE   RecName: Full=Alternative prion protein;
DE   AltName: Full=AltPrP;
//
ID   APRV1_HUMAN             Reviewed;         343 AA.
AC   Q53RT3; Q8N5P2; Q96LT3; Q96N43;
DE   RecName: Full=Retroviral-like aspartic protease 1;
DE            EC=3.4.23.-;
DE   AltName: Full=Skin-specific retroviral-like aspartic protease;
DE            Short=SASPase;
DE            Short=Skin aspartic protease;
DE   AltName: Full=TPA-inducible aspartic proteinase-like protein;
DE            Short=TAPS;
DE   Flags: Precursor;
GN   Name=ASPRV1; Synonyms=SASP;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0016485; P:protein processing; IDA:UniProtKB.
DR   GO; GO:0043588; P:skin development; ISS:UniProtKB.
//
ID   APR_HUMAN               Reviewed;          54 AA.
AC   Q13794; B2R4T7;
DE   RecName: Full=Phorbol-12-myristate-13-acetate-induced protein 1;
DE            Short=PMA-induced protein 1;
DE   AltName: Full=Immediate-early-response protein APR;
DE   AltName: Full=Protein Noxa;
GN   Name=PMAIP1; Synonyms=NOXA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IMP:MGI.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IMP:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:BHF-UCL.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0010917; P:negative regulation of mitochondrial membrane potential; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0010907; P:positive regulation of glucose metabolic process; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IDA:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0043331; P:response to dsRNA; IDA:HGNC.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; ISS:UniProtKB.
//
ID   APTX_HUMAN              Reviewed;         356 AA.
AC   Q7Z2E3; A8MTN4; D3DRK9; D3DRL0; Q0P662; Q5T781; Q5T782; Q5T784;
AC   Q6JV81; Q6JV82; Q6JV85; Q7Z2F3; Q7Z336; Q7Z5R5; Q7Z6V7; Q7Z6V8;
AC   Q9NXM5;
DE   RecName: Full=Aprataxin;
DE            EC=3.-.-.-;
DE   AltName: Full=Forkhead-associated domain histidine triad-like protein;
DE            Short=FHA-HIT;
GN   Name=APTX; Synonyms=AXA1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0033699; F:DNA 5'-adenosine monophosphate hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008967; F:phosphoglycolate phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
DR   GO; GO:0046403; F:polynucleotide 3'-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:GOC.
DR   GO; GO:0006266; P:DNA ligation; IEA:Ensembl.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0098506; P:polynucleotide 3' dephosphorylation; IDA:GOC.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0000012; P:single strand break repair; IDA:UniProtKB.
//
ID   APT_HUMAN               Reviewed;         180 AA.
AC   P07741; G5E9J2; Q3KP55; Q68DF9;
DE   RecName: Full=Adenine phosphoribosyltransferase;
DE            Short=APRT;
DE            EC=2.4.2.7;
GN   Name=APRT;
DR   GO; GO:0002055; F:adenine binding; IEA:Ensembl.
DR   GO; GO:0003999; F:adenine phosphoribosyltransferase activity; TAS:Reactome.
DR   GO; GO:0016208; F:AMP binding; IDA:MGI.
DR   GO; GO:0006168; P:adenine salvage; IEA:Ensembl.
DR   GO; GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AQ12A_HUMAN             Reviewed;         295 AA.
AC   Q8IXF9;
DE   RecName: Full=Aquaporin-12A;
DE            Short=AQP-12;
GN   Name=AQP12A; Synonyms=AQP12, AQPX2;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   AQ12B_HUMAN             Reviewed;         295 AA.
AC   A6NM10; A4QPB9;
DE   RecName: Full=Aquaporin-12B;
DE            Short=AQP-12B;
GN   Name=AQP12B;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   AQP10_HUMAN             Reviewed;         301 AA.
AC   Q96PS8; Q5VYD3; Q5VYD4; Q8NG70;
DE   RecName: Full=Aquaporin-10;
DE            Short=AQP-10;
DE   AltName: Full=Aquaglyceroporin-10;
DE   AltName: Full=Small intestine aquaporin;
GN   Name=AQP10;
DR   GuidetoPHARMACOLOGY; 697; -.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP11_HUMAN             Reviewed;         271 AA.
AC   Q8NBQ7;
DE   RecName: Full=Aquaporin-11;
DE            Short=AQP-11;
GN   Name=AQP11; Synonyms=AQPX1; ORFNames=PSEC0027;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0048388; P:endosomal lumen acidification; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0072014; P:proximal tubule development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP1_HUMAN              Reviewed;         269 AA.
AC   P29972; B5BU39; E7EM69; E9PC21; F5GY19; Q8TBI5; Q8TDC1;
DE   RecName: Full=Aquaporin-1;
DE            Short=AQP-1;
DE   AltName: Full=Aquaporin-CHIP;
DE   AltName: Full=Urine water channel;
DE   AltName: Full=Water channel protein for red blood cells and kidney proximal tubule;
GN   Name=AQP1; Synonyms=CHIP28;
DR   GuidetoPHARMACOLOGY; 688; -.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0035379; F:carbon dioxide transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015168; F:glycerol transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IDA:UniProtKB.
DR   GO; GO:0030184; F:nitric oxide transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005267; F:potassium channel activity; IMP:UniProtKB.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0022857; F:transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015250; F:water channel activity; IDA:UniProtKB.
DR   GO; GO:0005372; F:water transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0072488; P:ammonium transmembrane transport; IDA:GOC.
DR   GO; GO:0015696; P:ammonium transport; IDA:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0035378; P:carbon dioxide transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0015670; P:carbon dioxide transport; IDA:UniProtKB.
DR   GO; GO:0006884; P:cell volume homeostasis; IMP:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; IDA:UniProtKB.
DR   GO; GO:0071474; P:cellular hyperosmotic response; IMP:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0071280; P:cellular response to copper ion; IDA:UniProtKB.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IDA:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0071241; P:cellular response to inorganic substance; IDA:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IDA:UniProtKB.
DR   GO; GO:0071288; P:cellular response to mercury ion; IDA:UniProtKB.
DR   GO; GO:0071732; P:cellular response to nitric oxide; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0071472; P:cellular response to salt stress; IDA:UniProtKB.
DR   GO; GO:0033554; P:cellular response to stress; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0033326; P:cerebrospinal fluid secretion; IEP:UniProtKB.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:UniProtKB.
DR   GO; GO:0015793; P:glycerol transport; IDA:UniProtKB.
DR   GO; GO:0021670; P:lateral ventricle development; IEP:UniProtKB.
DR   GO; GO:0085018; P:maintenance of symbiont-containing vacuole by host; IMP:UniProtKB.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030185; P:nitric oxide transport; IDA:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; IEP:UniProtKB.
DR   GO; GO:0030157; P:pancreatic juice secretion; IEP:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0046878; P:positive regulation of saliva secretion; IMP:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006813; P:potassium ion transport; ISS:UniProtKB.
DR   GO; GO:0003097; P:renal water transport; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035377; P:transepithelial water transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; IDA:UniProtKB.
//
ID   AQP2_HUMAN              Reviewed;         271 AA.
AC   P41181; Q9UD68;
DE   RecName: Full=Aquaporin-2;
DE            Short=AQP-2;
DE   AltName: Full=ADH water channel;
DE   AltName: Full=Aquaporin-CD;
DE            Short=AQP-CD;
DE   AltName: Full=Collecting duct water channel protein;
DE   AltName: Full=WCH-CD;
DE   AltName: Full=Water channel protein for renal collecting duct;
GN   Name=AQP2;
DR   GuidetoPHARMACOLOGY; 689; -.
DR   GO; GO:0015168; F:glycerol transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015250; F:water channel activity; EXP:Reactome.
DR   GO; GO:0005372; F:water transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0030042; P:actin filament depolymerization; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0006884; P:cell volume homeostasis; IEA:Ensembl.
DR   GO; GO:0071280; P:cellular response to copper ion; IDA:UniProtKB.
DR   GO; GO:0071288; P:cellular response to mercury ion; IDA:UniProtKB.
DR   GO; GO:0042631; P:cellular response to water deprivation; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0015793; P:glycerol transport; IDA:UniProtKB.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0072205; P:metanephric collecting duct development; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0003097; P:renal water transport; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; IDA:UniProtKB.
//
ID   AQP3_HUMAN              Reviewed;         292 AA.
AC   Q92482; A8K843; B2RE16; D3DRL3; O00108; Q6FGT2; Q6FGW6;
DE   RecName: Full=Aquaporin-3;
DE            Short=AQP-3;
DE   AltName: Full=Aquaglyceroporin-3;
GN   Name=AQP3;
DR   GuidetoPHARMACOLOGY; 690; -.
DR   GO; GO:0015254; F:glycerol channel activity; IDA:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0015250; F:water channel activity; TAS:BHF-UCL.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0042476; P:odontogenesis; IEP:UniProtKB.
DR   GO; GO:0002684; P:positive regulation of immune system process; IDA:BHF-UCL.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; TAS:BHF-UCL.
DR   GO; GO:0070295; P:renal water absorption; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; TAS:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
DR   GO; GO:0033280; P:response to vitamin D; TAS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
DR   GO; GO:0015840; P:urea transport; IEA:Ensembl.
DR   GO; GO:0006833; P:water transport; TAS:BHF-UCL.
//
ID   AQP4_HUMAN              Reviewed;         323 AA.
AC   P55087; P78564;
DE   RecName: Full=Aquaporin-4;
DE            Short=AQP-4;
DE   AltName: Full=Mercurial-insensitive water channel;
DE            Short=MIWC;
DE   AltName: Full=WCH4;
GN   Name=AQP4;
DR   GO; GO:0015288; F:porin activity; IEA:Ensembl.
DR   GO; GO:0015250; F:water channel activity; EXP:Reactome.
DR   GO; GO:0005372; F:water transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015670; P:carbon dioxide transport; IEA:Ensembl.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0042538; P:hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IEP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0070295; P:renal water absorption; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP5_HUMAN              Reviewed;         265 AA.
AC   P55064; Q6FGW8;
DE   RecName: Full=Aquaporin-5;
DE            Short=AQP-5;
GN   Name=AQP5;
DR   GuidetoPHARMACOLOGY; 692; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015250; F:water channel activity; IDA:UniProtKB.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0015670; P:carbon dioxide transport; IDA:UniProtKB.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0042476; P:odontogenesis; IEP:UniProtKB.
DR   GO; GO:0030157; P:pancreatic juice secretion; IEP:UniProtKB.
DR   GO; GO:0046541; P:saliva secretion; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP6_HUMAN              Reviewed;         282 AA.
AC   Q13520;
DE   RecName: Full=Aquaporin-6;
DE            Short=AQP-6;
DE   AltName: Full=Aquaporin-2-like;
DE   AltName: Full=Kidney-specific aquaporin;
DE            Short=hKID;
GN   Name=AQP6; Synonyms=AQP2L;
DR   GuidetoPHARMACOLOGY; 693; -.
DR   GO; GO:0005253; F:anion channel activity; EXP:Reactome.
DR   GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015250; F:water channel activity; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0042476; P:odontogenesis; IEP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP73_HUMAN             Reviewed;         342 AA.
AC   A6NL99;
DE   RecName: Full=Putative aquaporin-7-like protein 3;
GN   Name=AQP7P3;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   AQP7_HUMAN              Reviewed;         342 AA.
AC   O14520; Q5T5L9; Q8NHM3;
DE   RecName: Full=Aquaporin-7;
DE            Short=AQP-7;
DE   AltName: Full=Aquaglyceroporin-7;
DE   AltName: Full=Aquaporin adipose;
DE            Short=AQPap;
DE   AltName: Full=Aquaporin-7-like;
GN   Name=AQP7; Synonyms=AQP7L, AQP9;
DR   GuidetoPHARMACOLOGY; 694; -.
DR   GO; GO:0015254; F:glycerol channel activity; EXP:Reactome.
DR   GO; GO:0015265; F:urea channel activity; IEA:Ensembl.
DR   GO; GO:0015250; F:water channel activity; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0015793; P:glycerol transport; TAS:Reactome.
DR   GO; GO:0070295; P:renal water absorption; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP8_HUMAN              Reviewed;         261 AA.
AC   O94778; Q8IUU3; Q9UIA4;
DE   RecName: Full=Aquaporin-8;
DE            Short=AQP-8;
GN   Name=AQP8;
DR   GuidetoPHARMACOLOGY; 695; -.
DR   GO; GO:0015250; F:water channel activity; TAS:ProtInc.
DR   GO; GO:0015722; P:canalicular bile acid transport; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   AQP9_HUMAN              Reviewed;         295 AA.
AC   O43315; Q9NP32;
DE   RecName: Full=Aquaporin-9;
DE            Short=AQP-9;
DE   AltName: Full=Aquaglyceroporin-9;
DE   AltName: Full=Small solute channel 1;
GN   Name=AQP9; Synonyms=SSC1;
DR   GuidetoPHARMACOLOGY; 696; -.
DR   GO; GO:0005275; F:amine transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0046943; F:carboxylic acid transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0015254; F:glycerol channel activity; EXP:Reactome.
DR   GO; GO:0015166; F:polyol transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0015288; F:porin activity; NAS:UniProtKB.
DR   GO; GO:0005345; F:purine nucleobase transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005350; F:pyrimidine nucleobase transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015250; F:water channel activity; IDA:UniProtKB.
DR   GO; GO:0005372; F:water transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0015837; P:amine transport; IDA:UniProtKB.
DR   GO; GO:0015722; P:canalicular bile acid transport; IEA:Ensembl.
DR   GO; GO:0046942; P:carboxylic acid transport; TAS:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.
DR   GO; GO:0007588; P:excretion; TAS:UniProtKB.
DR   GO; GO:0015793; P:glycerol transport; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:UniProtKB.
DR   GO; GO:0015791; P:polyol transport; IDA:UniProtKB.
DR   GO; GO:0006863; P:purine nucleobase transport; IDA:UniProtKB.
DR   GO; GO:0015855; P:pyrimidine nucleobase transport; IDA:UniProtKB.
DR   GO; GO:0072531; P:pyrimidine-containing compound transmembrane transport; IDA:GOC.
DR   GO; GO:0046689; P:response to mercury ion; IDA:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IDA:UniProtKB.
DR   GO; GO:0006970; P:response to osmotic stress; TAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:UniProtKB.
DR   GO; GO:0030104; P:water homeostasis; NAS:UniProtKB.
DR   GO; GO:0006833; P:water transport; IDA:UniProtKB.
//
ID   AQR_HUMAN               Reviewed;        1485 AA.
AC   O60306; A0JP17; A5YKK3; Q2YDX9; Q6IRU8; Q6PIC8;
DE   RecName: Full=Intron-binding protein aquarius;
DE   AltName: Full=Intron-binding protein of 160 kDa;
DE            Short=IBP160;
GN   Name=AQR; Synonyms=KIAA0560;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0097157; F:pre-mRNA intronic binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   AR13A_HUMAN             Reviewed;         290 AA.
AC   Q5H913; B2RTT6; B4DX50;
DE   RecName: Full=ADP-ribosylation factor-like protein 13A;
GN   Name=ARL13A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   AR13B_HUMAN             Reviewed;         428 AA.
AC   Q3SXY8; D3DN29; G3V1S8; Q504W8; Q8TCL5;
DE   RecName: Full=ADP-ribosylation factor-like protein 13B;
DE   AltName: Full=ADP-ribosylation factor-like protein 2-like 1;
DE            Short=ARL2-like protein 1;
GN   Name=ARL13B; Synonyms=ARL2L1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0021943; P:formation of radial glial scaffolds; ISS:UniProtKB.
DR   GO; GO:0021830; P:interneuron migration from the subpallium to the cortex; ISS:UniProtKB.
DR   GO; GO:0021532; P:neural tube patterning; ISS:UniProtKB.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   AR26L_HUMAN             Reviewed;         321 AA.
AC   Q6NSI1;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein 26-like protein;
GN   Name=ANKRD26P1;
//
ID   AR2BP_HUMAN             Reviewed;         163 AA.
AC   Q9Y2Y0; B3KQJ5; Q504R0;
DE   RecName: Full=ADP-ribosylation factor-like protein 2-binding protein;
DE            Short=ARF-like 2-binding protein;
DE            Short=ARL2-binding protein;
DE   AltName: Full=Binder of ARF2 protein 1;
GN   Name=ARL2BP; Synonyms=BART, BART1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IMP:UniProtKB.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IMP:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   AR6P1_HUMAN             Reviewed;         203 AA.
AC   Q15041;
DE   RecName: Full=ADP-ribosylation factor-like protein 6-interacting protein 1;
DE            Short=ARL-6-interacting protein 1;
DE            Short=Aip-1;
GN   Name=ARL6IP1; Synonyms=ARL6IP, KIAA0069;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; IEA:Ensembl.
//
ID   AR6P4_HUMAN             Reviewed;         360 AA.
AC   Q66PJ3; A4UCR8; B3V0L0; B3V0L1; Q4F966; Q504R8; Q96BI2; Q9NR05;
AC   Q9P2R9;
DE   RecName: Full=ADP-ribosylation factor-like protein 6-interacting protein 4;
DE            Short=ARL-6-interacting protein 4;
DE            Short=Aip-4;
DE   AltName: Full=HSP-975;
DE   AltName: Full=HSVI-binding protein;
DE   AltName: Full=SR-15;
DE   AltName: Full=SRp25;
DE            Short=SR-25;
DE   AltName: Full=Splicing factor SRrp37;
GN   Name=ARL6IP4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   AR6P6_HUMAN             Reviewed;         226 AA.
AC   Q8N6S5; B2RDS6; Q7Z4G7;
DE   RecName: Full=ADP-ribosylation factor-like protein 6-interacting protein 6;
DE            Short=ARL-6-interacting protein 6;
DE            Short=Aip-6;
DE   AltName: Full=Phosphonoformate immuno-associated protein 1;
GN   Name=ARL6IP6; Synonyms=PFAAP1;
//
ID   ARAF_HUMAN              Reviewed;         606 AA.
AC   P10398; P07557; Q5H9B2; Q5H9B3;
DE   RecName: Full=Serine/threonine-protein kinase A-Raf;
DE            EC=2.7.11.1;
DE   AltName: Full=Proto-oncogene A-Raf;
DE   AltName: Full=Proto-oncogene A-Raf-1;
DE   AltName: Full=Proto-oncogene Pks;
GN   Name=ARAF; Synonyms=ARAF1, PKS, PKS2;
DR   GuidetoPHARMACOLOGY; 1933; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0032006; P:regulation of TOR signaling; IMP:UniProtKB.
//
ID   ARAID_HUMAN             Reviewed;         229 AA.
AC   Q6UW56; A8C1S2; A8K779; Q96FF6; Q96RT2; Q9Y2R7; Q9Y5L7;
DE   RecName: Full=All-trans retinoic acid-induced differentiation factor;
DE   AltName: Full=Apoptosis-related protein 3;
DE            Short=APR-3;
DE   AltName: Full=p18;
DE   Flags: Precursor;
GN   Name=ATRAID; Synonyms=APR3, C2orf28; ORFNames=HSPC013, UNQ214/PRO240;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:2000599; P:negative regulation of cyclin catabolic process; IDA:UniProtKB.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IDA:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:UniProtKB.
//
ID   ARAP1_HUMAN             Reviewed;        1450 AA.
AC   Q96P48; A3KLL7; B2RTS2; O94879; Q4LDD5; Q59FI7; Q6PHS3; Q8WU51;
AC   Q96HP6; Q96L71;
DE   RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1;
DE   AltName: Full=Centaurin-delta-2;
DE            Short=Cnt-d2;
GN   Name=ARAP1; Synonyms=CENTD2, KIAA0782;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.
DR   GO; GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IEA:Ensembl.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARAP2_HUMAN             Reviewed;        1704 AA.
AC   Q8WZ64; Q4W5D2; Q7Z2L5; Q96L70; Q96P49; Q9Y4E4;
DE   RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2;
DE   AltName: Full=Centaurin-delta-1;
DE            Short=Cnt-d1;
DE   AltName: Full=Protein PARX;
GN   Name=ARAP2; Synonyms=CENTD1, KIAA0580;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARAP3_HUMAN             Reviewed;        1544 AA.
AC   Q8WWN8; D3DQE3;
DE   RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3;
DE   AltName: Full=Centaurin-delta-3;
DE            Short=Cnt-d3;
GN   Name=ARAP3; Synonyms=CENTD3;
DR   GO; GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0035021; P:negative regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
//
ID   ARAS1_HUMAN             Reviewed;          56 AA.
AC   Q96IT6; B2RAE2; D3DS88;
DE   RecName: Full=Putative uncharacterized protein ARHGAP5-AS1;
DE   AltName: Full=ARHGAP5 antisense RNA 1;
DE   AltName: Full=ARHGAP5 antisense gene protein 1;
GN   Name=ARHGAP5-AS1; Synonyms=C14orf128;
//
ID   ARBK1_HUMAN             Reviewed;         689 AA.
AC   P25098; B0ZBE1; Q13837; Q6GTT3;
DE   RecName: Full=Beta-adrenergic receptor kinase 1;
DE            Short=Beta-ARK-1;
DE            EC=2.7.11.15;
DE   AltName: Full=G-protein coupled receptor kinase 2;
GN   Name=ADRBK1; Synonyms=BARK, BARK1, GRK2;
DR   GuidetoPHARMACOLOGY; 1466; -.
DR   GO; GO:0031694; F:alpha-2A adrenergic receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; IDA:UniProtKB.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045988; P:negative regulation of striated muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0003108; P:negative regulation of the force of heart contraction by chemical signal; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0033605; P:positive regulation of catecholamine secretion; ISS:BHF-UCL.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   ARBK2_HUMAN             Reviewed;         688 AA.
AC   P35626; Q9UGW9;
DE   RecName: Full=Beta-adrenergic receptor kinase 2;
DE            Short=Beta-ARK-2;
DE            EC=2.7.11.15;
DE   AltName: Full=G-protein-coupled receptor kinase 3;
GN   Name=ADRBK2; Synonyms=BARK2, GRK3;
DR   GuidetoPHARMACOLOGY; 1467; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047696; F:beta-adrenergic receptor kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   ARC1A_HUMAN             Reviewed;         370 AA.
AC   Q92747; A4D276; D6W5S1; Q7Z5U8; Q86WU5; Q8IXQ0;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 1A;
DE   AltName: Full=SOP2-like protein;
GN   Name=ARPC1A; Synonyms=SOP2L;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
//
ID   ARC1B_HUMAN             Reviewed;         372 AA.
AC   O15143; Q9BU00;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 1B;
DE   AltName: Full=Arp2/3 complex 41 kDa subunit;
DE   AltName: Full=p41-ARC;
GN   Name=ARPC1B; Synonyms=ARC41;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
//
ID   ARCH_HUMAN              Reviewed;         167 AA.
AC   Q8IWT0; Q5TGK5; Q6PDA1; Q8IWS9; Q8NEV6; Q8NEV7;
DE   RecName: Full=Protein archease;
DE   AltName: Full=Protein ZBTB8OS;
DE   AltName: Full=Zinc finger and BTB domain-containing opposite strand protein 8;
GN   Name=ZBTB8OS; Synonyms=ARCH;
//
ID   ARC_HUMAN               Reviewed;         396 AA.
AC   Q7LC44; Q9UJW6; Q9Y469;
DE   RecName: Full=Activity-regulated cytoskeleton-associated protein;
DE   AltName: Full=ARC/ARG3.1;
DE   AltName: Full=Activity-regulated gene 3.1 protein homolog;
DE            Short=Arg3.1;
GN   Name=ARC; Synonyms=KIAA0278;
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
//
ID   AREG_HUMAN              Reviewed;         252 AA.
AC   P15514; Q5U026;
DE   RecName: Full=Amphiregulin;
DE            Short=AR;
DE   AltName: Full=Colorectum cell-derived growth factor;
DE            Short=CRDGF;
DE   Flags: Precursor;
GN   Name=AREG; Synonyms=SDGF;
GN   and
GN   Name=AREGB;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.
//
ID   AREL1_HUMAN             Reviewed;         823 AA.
AC   O15033; B4E2C7; Q7LDY1; Q8IYY9;
DE   RecName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1;
DE            EC=6.3.2.-;
GN   Name=AREL1; Synonyms=KIAA0317;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   ARF1_HUMAN              Reviewed;         181 AA.
AC   P84077; P10947; P32889;
DE   RecName: Full=ADP-ribosylation factor 1;
GN   Name=ARF1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0097061; P:dendritic spine organization; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0060292; P:long term synaptic depression; ISS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0034315; P:regulation of Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0002090; P:regulation of receptor internalization; ISS:UniProtKB.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ARF3_HUMAN              Reviewed;         181 AA.
AC   P61204; A8K6G8; P16587;
DE   RecName: Full=ADP-ribosylation factor 3;
GN   Name=ARF3;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ARF4_HUMAN              Reviewed;         180 AA.
AC   P18085; B2R7J7; P21371;
DE   RecName: Full=ADP-ribosylation factor 4;
GN   Name=ARF4; Synonyms=ARF2;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:UniProt.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031584; P:activation of phospholipase D activity; IDA:UniProt.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IDA:UniProt.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProt.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProt.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IDA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IDA:UniProt.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ARF5_HUMAN              Reviewed;         180 AA.
AC   P84085; P26437;
DE   RecName: Full=ADP-ribosylation factor 5;
GN   Name=ARF5;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ARF6_HUMAN              Reviewed;         175 AA.
AC   P62330; P26438; Q6FGZ2;
DE   RecName: Full=ADP-ribosylation factor 6;
GN   Name=ARF6;
DR   GO; GO:0005525; F:GTP binding; TAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0033028; P:myeloid cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0034394; P:protein localization to cell surface; ISS:BHF-UCL.
DR   GO; GO:0036010; P:protein localization to endosome; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060998; P:regulation of dendritic spine development; ISS:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0035020; P:regulation of Rac protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0031529; P:ruffle organization; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
//
ID   ARFG1_HUMAN             Reviewed;         406 AA.
AC   Q8N6T3; B7ZBI3; E1P5I9; Q6PK71; Q96KC4; Q96T02; Q9NSU3; Q9NVF6;
AC   Q9UIL0;
DE   RecName: Full=ADP-ribosylation factor GTPase-activating protein 1;
DE            Short=ARF GAP 1;
DE   AltName: Full=ADP-ribosylation factor 1 GTPase-activating protein;
DE            Short=ARF1 GAP;
DE   AltName: Full=ARF1-directed GTPase-activating protein;
GN   Name=ARFGAP1; Synonyms=ARF1GAP;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
//
ID   ARFG2_HUMAN             Reviewed;         521 AA.
AC   Q8N6H7; D3DQQ9; Q3LIF2; Q8N3I1; Q96SX7;
DE   RecName: Full=ADP-ribosylation factor GTPase-activating protein 2;
DE            Short=ARF GAP 2;
DE   AltName: Full=GTPase-activating protein ZNF289;
DE   AltName: Full=Zinc finger protein 289;
GN   Name=ARFGAP2; Synonyms=ZNF289; ORFNames=Nbla10535;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ARFG3_HUMAN             Reviewed;         516 AA.
AC   Q9NP61; E9PB03; Q9BSC6; Q9H9J0; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4;
DE   RecName: Full=ADP-ribosylation factor GTPase-activating protein 3;
DE            Short=ARF GAP 3;
GN   Name=ARFGAP3; Synonyms=ARFGAP1;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0009306; P:protein secretion; IEP:UniProtKB.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
//
ID   ARFP1_HUMAN             Reviewed;         373 AA.
AC   P53367; Q2M2X4; Q3SYL4; Q9Y2X6;
DE   RecName: Full=Arfaptin-1;
DE   AltName: Full=ADP-ribosylation factor-interacting protein 1;
GN   Name=ARFIP1;
DR   GO; GO:0006886; P:intracellular protein transport; IDA:MGI.
DR   GO; GO:0050708; P:regulation of protein secretion; IDA:MGI.
//
ID   ARFP2_HUMAN             Reviewed;         341 AA.
AC   P53365; B4DX86; B4E306; D3DQT5;
DE   RecName: Full=Arfaptin-2;
DE   AltName: Full=ADP-ribosylation factor-interacting protein 2;
DE   AltName: Full=Partner of RAC1;
DE            Short=Protein POR1;
GN   Name=ARFIP2; Synonyms=POR1;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048365; F:Rac GTPase binding; TAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0030032; P:lamellipodium assembly; TAS:UniProtKB.
DR   GO; GO:0031529; P:ruffle organization; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   ARFRP_HUMAN             Reviewed;         201 AA.
AC   Q13795; B7ZKX7; E1P5J9; Q6IBQ0;
DE   RecName: Full=ADP-ribosylation factor-related protein 1;
DE            Short=ARF-related protein 1;
DE            Short=ARP;
GN   Name=ARFRP1; Synonyms=ARP1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IMP:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARG28_HUMAN             Reviewed;        1705 AA.
AC   Q8N1W1; B2RXG7; B4E3K4; B5MDA3; B7ZW32; E9PC75; Q8NCM7; Q96E37;
AC   Q9H6L3; Q9H6W0;
DE   RecName: Full=Rho guanine nucleotide exchange factor 28;
DE   AltName: Full=190 kDa guanine nucleotide exchange factor;
DE            Short=p190-RhoGEF;
DE            Short=p190RhoGEF;
DE   AltName: Full=Rho guanine nucleotide exchange factor;
GN   Name=ARHGEF28; Synonyms=KIAA1998, RGNEF;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0021955; P:central nervous system neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0060052; P:neurofilament cytoskeleton organization; IEA:Ensembl.
//
ID   ARG33_HUMAN             Reviewed;         844 AA.
AC   A8MVX0; J3KPX2;
DE   RecName: Full=Rho guanine nucleotide exchange factor 33;
GN   Name=ARHGEF33;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARG35_HUMAN             Reviewed;         484 AA.
AC   A5YM69; Q6ZUI2;
DE   RecName: Full=Rho guanine nucleotide exchange factor 35;
DE   AltName: Full=Rho guanine nucleotide exchange factor 5-like protein;
GN   Name=ARHGEF35; Synonyms=ARHGEF5L;
//
ID   ARG39_HUMAN             Reviewed;         335 AA.
AC   Q8N4T4; Q49AG0; Q6TPQ2; Q96ST6;
DE   RecName: Full=Rho guanine nucleotide exchange factor 39;
GN   Name=ARHGEF39; Synonyms=C9orf100;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
//
ID   ARGAL_HUMAN             Reviewed;        1279 AA.
AC   Q9HCE6; B7ZKS1; Q17RW1; Q3YFJ4; Q5VXI5; Q5VXI6; Q66K51; Q6P0L7;
AC   Q8NAV5; Q9NVT3;
DE   RecName: Full=Rho guanine nucleotide exchange factor 10-like protein;
DE   AltName: Full=GrinchGEF;
GN   Name=ARHGEF10L; Synonyms=GRINCHGEF, KIAA1626;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARGFX_HUMAN             Reviewed;         315 AA.
AC   A6NJG6;
DE   RecName: Full=Arginine-fifty homeobox;
GN   Name=ARGFX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARGI1_HUMAN             Reviewed;         322 AA.
AC   P05089; A6NEA0; Q5JWT5; Q5JWT6; Q8TE72; Q9BS50;
DE   RecName: Full=Arginase-1;
DE            EC=3.5.3.1;
DE   AltName: Full=Liver-type arginase;
DE   AltName: Full=Type I arginase;
GN   Name=ARG1;
DR   GO; GO:0004053; F:arginase activity; EXP:Reactome.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0006527; P:arginine catabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0032964; P:collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060056; P:mammary gland involution; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:Ensembl.
DR   GO; GO:0010963; P:regulation of L-arginine import; IEA:Ensembl.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IEA:Ensembl.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0010269; P:response to selenium ion; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
//
ID   ARGI2_HUMAN             Reviewed;         354 AA.
AC   P78540; B2R690; Q6FHY8;
DE   RecName: Full=Arginase-2, mitochondrial;
DE            EC=3.5.3.1;
DE   AltName: Full=Kidney-type arginase;
DE   AltName: Full=Non-hepatic arginase;
DE   AltName: Full=Type II arginase;
DE   Flags: Precursor;
GN   Name=ARG2;
DR   GO; GO:0004053; F:arginase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006941; P:striated muscle contraction; IEA:Ensembl.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   ARGL1_HUMAN             Reviewed;         273 AA.
AC   Q9NWB6; B4E0Y3; Q5T257; Q6IQ34;
DE   RecName: Full=Arginine and glutamate-rich protein 1;
GN   Name=ARGLU1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARH37_HUMAN             Reviewed;         675 AA.
AC   A1IGU5; Q6ZW51;
DE   RecName: Full=Rho guanine nucleotide exchange factor 37;
GN   Name=ARHGEF37;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARH38_HUMAN             Reviewed;         777 AA.
AC   Q9NXL2; C9JIB4;
DE   RecName: Full=Rho guanine nucleotide exchange factor 38;
GN   Name=ARHGEF38;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARH40_HUMAN             Reviewed;        1519 AA.
AC   Q8TER5; A5PL07; Q9BWP5; Q9H7L6; Q9NTF9; Q9NW24;
DE   RecName: Full=Rho guanine nucleotide exchange factor 40;
DE   AltName: Full=Protein SOLO;
GN   Name=ARHGEF40; Synonyms=SOLO;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARHG1_HUMAN             Reviewed;         912 AA.
AC   Q92888; O00513; Q8N4J4; Q96BF4; Q96F17; Q9BSB1;
DE   RecName: Full=Rho guanine nucleotide exchange factor 1;
DE   AltName: Full=115 kDa guanine nucleotide exchange factor;
DE            Short=p115-RhoGEF;
DE            Short=p115RhoGEF;
DE   AltName: Full=Sub1.5;
GN   Name=ARHGEF1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   ARHG2_HUMAN             Reviewed;         986 AA.
AC   Q92974; D3DVA6; O75142; Q15079; Q5VY92; Q8TDA3; Q8WUG4; Q9H023;
DE   RecName: Full=Rho guanine nucleotide exchange factor 2;
DE   AltName: Full=Guanine nucleotide exchange factor H1;
DE            Short=GEF-H1;
DE   AltName: Full=Microtubule-regulated Rho-GEF;
DE   AltName: Full=Proliferating cell nucleolar antigen p40;
GN   Name=ARHGEF2; Synonyms=KIAA0651, LFP40;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0017048; F:Rho GTPase binding; IDA:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0071474; P:cellular hyperosmotic response; ISS:BHF-UCL.
DR   GO; GO:0071225; P:cellular response to muramyl dipeptide; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:BHF-UCL.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; ISS:BHF-UCL.
DR   GO; GO:1902219; P:negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; ISS:BHF-UCL.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.
DR   GO; GO:0060546; P:negative regulation of necroptotic process; ISS:BHF-UCL.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHG3_HUMAN             Reviewed;         526 AA.
AC   Q9NR81; A8K5U7; Q4FZB6; Q4QQI5; Q4QQQ0; Q59F00; Q6NUN3; Q7Z4U2;
AC   Q7Z5T2; Q9H7T4;
DE   RecName: Full=Rho guanine nucleotide exchange factor 3;
DE   AltName: Full=Exchange factor found in platelets and leukemic and neuronal tissues;
DE            Short=XPLN;
GN   Name=ARHGEF3;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHG4_HUMAN             Reviewed;         690 AA.
AC   Q9NR80; Q9HDC6; Q9UPP0;
DE   RecName: Full=Rho guanine nucleotide exchange factor 4;
DE   AltName: Full=APC-stimulated guanine nucleotide exchange factor 1;
DE            Short=Asef;
DE            Short=Asef1;
GN   Name=ARHGEF4; Synonyms=KIAA1112;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0046847; P:filopodium assembly; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043087; P:regulation of GTPase activity; IMP:GOC.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IMP:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHG5_HUMAN             Reviewed;        1597 AA.
AC   Q12774; A6NNJ2; Q6ZML7;
DE   RecName: Full=Rho guanine nucleotide exchange factor 5;
DE   AltName: Full=Ephexin-3;
DE   AltName: Full=Guanine nucleotide regulatory protein TIM;
DE   AltName: Full=Oncogene TIM;
DE   AltName: Full=Transforming immortalized mammary oncogene;
DE   AltName: Full=p60 TIM;
GN   Name=ARHGEF5; Synonyms=TIM;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0002408; P:myeloid dendritic cell chemotaxis; IEA:Ensembl.
DR   GO; GO:0071803; P:positive regulation of podosome assembly; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:MGI.
//
ID   ARHG6_HUMAN             Reviewed;         776 AA.
AC   Q15052; A6NMW9; A8K6S7; B1AL37; Q15396; Q5JQ66; Q7Z3W1; Q86XH0;
DE   RecName: Full=Rho guanine nucleotide exchange factor 6;
DE   AltName: Full=Alpha-Pix;
DE   AltName: Full=COOL-2;
DE   AltName: Full=PAK-interacting exchange factor alpha;
DE   AltName: Full=Rac/Cdc42 guanine nucleotide exchange factor 6;
GN   Name=ARHGEF6; Synonyms=COOL2, KIAA0006, PIXA;
DR   GO; GO:0005096; F:GTPase activator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; NAS:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; NAS:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; NAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHG7_HUMAN             Reviewed;         803 AA.
AC   Q14155; B1ALK6; B1ALK8; Q3LIA4; Q5W9H0; Q6P9G3; Q6PII2; Q86W63;
AC   Q8N3M1;
DE   RecName: Full=Rho guanine nucleotide exchange factor 7;
DE   AltName: Full=Beta-Pix;
DE   AltName: Full=COOL-1;
DE   AltName: Full=PAK-interacting exchange factor beta;
DE   AltName: Full=p85;
GN   Name=ARHGEF7; Synonyms=COOL1, KIAA0142, P85SPR, PAK3BP, PIXB;
GN   ORFNames=Nbla10314;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHG8_HUMAN             Reviewed;         596 AA.
AC   Q7Z628; Q12773; Q96D82; Q99903; Q9UEN6;
DE   RecName: Full=Neuroepithelial cell-transforming gene 1 protein;
DE   AltName: Full=Proto-oncogene p65 Net1;
DE   AltName: Full=Rho guanine nucleotide exchange factor 8;
GN   Name=NET1; Synonyms=ARHGEF8;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IMP:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHG9_HUMAN             Reviewed;         516 AA.
AC   O43307; A8K1S8; B4DHC7; F8W7P8; Q5JSL6;
DE   RecName: Full=Rho guanine nucleotide exchange factor 9;
DE   AltName: Full=Collybistin;
DE   AltName: Full=PEM-2 homolog;
DE   AltName: Full=Rac/Cdc42 guanine nucleotide exchange factor 9;
GN   Name=ARHGEF9; Synonyms=ARHDH9, KIAA0424;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ARHGA_HUMAN             Reviewed;        1369 AA.
AC   O15013; O14665; Q2KHR8; Q68D55; Q8IWD9; Q8IY77;
DE   RecName: Full=Rho guanine nucleotide exchange factor 10;
GN   Name=ARHGEF10; Synonyms=KIAA0294;
DR   GO; GO:0019894; F:kinesin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:BHF-UCL.
DR   GO; GO:0051298; P:centrosome duplication; IMP:BHF-UCL.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IMP:BHF-UCL.
DR   GO; GO:0033126; P:positive regulation of GTP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:BHF-UCL.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IMP:BHF-UCL.
//
ID   ARHGB_HUMAN             Reviewed;        1522 AA.
AC   O15085; D3DVD0; Q5VY40; Q6PFW2;
DE   RecName: Full=Rho guanine nucleotide exchange factor 11;
DE   AltName: Full=PDZ-RhoGEF;
GN   Name=ARHGEF11; Synonyms=KIAA0380;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IDA:MGI.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; NAS:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006941; P:striated muscle contraction; NAS:UniProtKB.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   ARHGC_HUMAN             Reviewed;        1544 AA.
AC   Q9NZN5; O15086; Q6P526;
DE   RecName: Full=Rho guanine nucleotide exchange factor 12;
DE   AltName: Full=Leukemia-associated RhoGEF;
GN   Name=ARHGEF12; Synonyms=KIAA0382, LARG;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IDA:MGI.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:MGI.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   ARHGF_HUMAN             Reviewed;         841 AA.
AC   O94989; A8K6G1; Q8N449; Q9H8B4;
DE   RecName: Full=Rho guanine nucleotide exchange factor 15;
DE   AltName: Full=Ephexin-5;
DE            Short=E5;
DE   AltName: Full=Vsm-RhoGEF;
GN   Name=ARHGEF15; Synonyms=KIAA0915;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:2000297; P:negative regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl.
//
ID   ARHGG_HUMAN             Reviewed;         709 AA.
AC   Q5VV41; Q86TF0; Q99434;
DE   RecName: Full=Rho guanine nucleotide exchange factor 16;
DE   AltName: Full=Ephexin-4;
GN   Name=ARHGEF16; Synonyms=EPHEXIN4, NBR;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0017048; F:Rho GTPase binding; IPI:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032864; P:activation of Cdc42 GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHGH_HUMAN             Reviewed;        2063 AA.
AC   Q96PE2; B2RP20; Q86XU2; Q8N2S0; Q9Y4G3;
DE   RecName: Full=Rho guanine nucleotide exchange factor 17;
DE   AltName: Full=164 kDa Rho-specific guanine-nucleotide exchange factor;
DE            Short=p164-RhoGEF;
DE            Short=p164RhoGEF;
DE   AltName: Full=Tumor endothelial marker 4;
GN   Name=ARHGEF17; Synonyms=KIAA0337, TEM4;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:MGI.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   ARHGI_HUMAN             Reviewed;        1173 AA.
AC   Q6ZSZ5; A8MV62; B5ME81; O60274; Q6DD92;
DE   RecName: Full=Rho guanine nucleotide exchange factor 18;
DE   AltName: Full=114 kDa Rho-specific guanine nucleotide exchange factor;
DE            Short=p114-Rho-GEF;
DE            Short=p114RhoGEF;
DE   AltName: Full=Septin-associated RhoGEF;
DE            Short=SA-RhoGEF;
GN   Name=ARHGEF18; Synonyms=KIAA0521;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:MGI.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:MGI.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   ARHGJ_HUMAN             Reviewed;         802 AA.
AC   Q8IW93; A6NJ04; Q5TEV2; Q6PJQ4; Q8N244;
DE   RecName: Full=Rho guanine nucleotide exchange factor 19;
DE   AltName: Full=Ephexin-2;
GN   Name=ARHGEF19;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IGI:MGI.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   ARHGP_HUMAN             Reviewed;         580 AA.
AC   Q86VW2; A6NJH5; A9CQZ6; F8W7Z4; Q8WV84; Q96E63;
DE   RecName: Full=Rho guanine nucleotide exchange factor 25;
DE   AltName: Full=Guanine nucleotide exchange factor GEFT;
DE   AltName: Full=Rac/Cdc42/Rho exchange factor GEFT;
DE   AltName: Full=RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT;
DE   AltName: Full=p63RhoGEF;
GN   Name=ARHGEF25; Synonyms=GEFT;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARHGQ_HUMAN             Reviewed;         871 AA.
AC   Q96DR7; B3KVP8; E9PBD0; Q68CL1; Q6AZ96; Q6Q8Q8; Q96AW8; Q96DR6;
AC   Q9H9D7; Q9H9R2; Q9UFW5;
DE   RecName: Full=Rho guanine nucleotide exchange factor 26;
DE   AltName: Full=SH3 domain-containing guanine exchange factor;
GN   Name=ARHGEF26; Synonyms=SGEF; ORFNames=HMFN1864;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ARH_HUMAN               Reviewed;         308 AA.
AC   Q5SW96; A2BHI5; Q6TQS9; Q8N2Y0; Q9UFI9;
DE   RecName: Full=Low density lipoprotein receptor adapter protein 1;
DE   AltName: Full=Autosomal recessive hypercholesterolemia protein;
GN   Name=LDLRAP1; Synonyms=ARH;
DR   GO; GO:0035612; F:AP-2 adaptor complex binding; IDA:BHF-UCL.
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:BHF-UCL.
DR   GO; GO:0035615; F:clathrin adaptor activity; IDA:BHF-UCL.
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProtKB.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; IMP:UniProtKB.
DR   GO; GO:0035591; F:signaling adaptor activity; IDA:BHF-UCL.
DR   GO; GO:0042982; P:amyloid precursor protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.
DR   GO; GO:0090205; P:positive regulation of cholesterol metabolic process; IC:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IDA:GOC.
DR   GO; GO:0031623; P:receptor internalization; IMP:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0090118; P:receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; IMP:BHF-UCL.
DR   GO; GO:0090003; P:regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0043393; P:regulation of protein binding; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   ARI1A_HUMAN             Reviewed;        2285 AA.
AC   O14497; D3DPL1; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89;
AC   Q9BY33; Q9HBJ5; Q9UPZ1;
DE   RecName: Full=AT-rich interactive domain-containing protein 1A;
DE            Short=ARID domain-containing protein 1A;
DE   AltName: Full=B120;
DE   AltName: Full=BRG1-associated factor 250;
DE            Short=BAF250;
DE   AltName: Full=BRG1-associated factor 250a;
DE            Short=BAF250A;
DE   AltName: Full=Osa homolog 1;
DE            Short=hOSA1;
DE   AltName: Full=SWI-like protein;
DE   AltName: Full=SWI/SNF complex protein p270;
DE   AltName: Full=SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1;
DE   AltName: Full=hELD;
GN   Name=ARID1A; Synonyms=BAF250, BAF250A, C1orf4, OSA1, SMARCF1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0003205; P:cardiac chamber development; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; TAS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0042921; P:glucocorticoid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0042766; P:nucleosome mobilization; TAS:UniProtKB.
DR   GO; GO:0003408; P:optic cup formation involved in camera-type eye development; IEA:Ensembl.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARHL1_HUMAN             Reviewed;         354 AA.
AC   Q8NDY3; Q5JUG2; Q96GD1;
DE   RecName: Full=[Protein ADP-ribosylarginine] hydrolase-like protein 1;
DE            EC=3.2.-.-;
DE   AltName: Full=ADP-ribosylhydrolase 2;
GN   Name=ADPRHL1; Synonyms=ARH2;
DR   GO; GO:0003875; F:ADP-ribosylarginine hydrolase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051725; P:protein de-ADP-ribosylation; IEA:InterPro.
//
ID   ARI1B_HUMAN             Reviewed;        2236 AA.
AC   Q8NFD5; Q5JRD1; Q5VYC4; Q8IZY8; Q8TEV0; Q8TF02; Q99491; Q9ULI5;
DE   RecName: Full=AT-rich interactive domain-containing protein 1B;
DE            Short=ARID domain-containing protein 1B;
DE   AltName: Full=BRG1-associated factor 250b;
DE            Short=BAF250B;
DE   AltName: Full=BRG1-binding protein hELD/OSA1;
DE   AltName: Full=Osa homolog 2;
DE            Short=hOsa2;
DE   AltName: Full=p250R;
GN   Name=ARID1B; Synonyms=BAF250B, DAN15, KIAA1235, OSA2;
DR   GO; GO:0003677; F:DNA binding; IDA:GDB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARHL2_HUMAN             Reviewed;         363 AA.
AC   Q9NX46; Q53G94; Q6IAB8; Q9BY47;
DE   RecName: Full=Poly(ADP-ribose) glycohydrolase ARH3;
DE            EC=3.2.1.143;
DE   AltName: Full=ADP-ribosylhydrolase 3;
DE   AltName: Full=[Protein ADP-ribosylarginine] hydrolase-like protein 2;
DE   Flags: Precursor;
GN   Name=ADPRHL2; Synonyms=ARH3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004649; F:poly(ADP-ribose) glycohydrolase activity; IEA:UniProtKB-EC.
//
ID   ARI1_HUMAN              Reviewed;         557 AA.
AC   Q9Y4X5; B2R6U3; O76026; Q9H3T6; Q9UEN0; Q9UP39;
DE   RecName: Full=E3 ubiquitin-protein ligase ARIH1;
DE            EC=6.3.2.-;
DE   AltName: Full=H7-AP2;
DE   AltName: Full=HHARI;
DE   AltName: Full=Monocyte protein 6;
DE            Short=MOP-6;
DE   AltName: Full=Protein ariadne-1 homolog;
DE            Short=ARI-1;
DE   AltName: Full=UbcH7-binding protein;
DE   AltName: Full=UbcM4-interacting protein;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-binding protein 1;
GN   Name=ARIH1; Synonyms=ARI, MOP6, UBCH7BP; ORFNames=HUSSY-27;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019787; F:small conjugating protein ligase activity; TAS:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
//
ID   ARI2O_HUMAN             Reviewed;         290 AA.
AC   Q8N7S6;
DE   RecName: Full=Uncharacterized protein ARIH2OS;
DE   AltName: Full=Ariadne-2 homolog opposite strand protein;
GN   Name=ARIH2OS; Synonyms=C3orf71;
//
ID   ARI2_HUMAN              Reviewed;         493 AA.
AC   O95376; Q9HBZ6; Q9UEM9;
DE   RecName: Full=E3 ubiquitin-protein ligase ARIH2;
DE            Short=ARI-2;
DE            Short=Protein ariadne-2 homolog;
DE            EC=6.3.2.-;
DE   AltName: Full=Triad1 protein;
GN   Name=ARIH2; Synonyms=ARI2, TRIAD1; ORFNames=HT005;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0048588; P:developmental cell growth; IDA:UniProtKB.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   ARI3A_HUMAN             Reviewed;         593 AA.
AC   Q99856; Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3;
DE   RecName: Full=AT-rich interactive domain-containing protein 3A;
DE            Short=ARID domain-containing protein 3A;
DE   AltName: Full=B-cell regulator of IgH transcription;
DE            Short=Bright;
DE   AltName: Full=Dead ringer-like protein 1;
DE   AltName: Full=E2F-binding protein 1;
GN   Name=ARID3A; Synonyms=DRIL1, DRIL3, DRX, E2FBP1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARI3B_HUMAN             Reviewed;         561 AA.
AC   Q8IVW6; O95443; Q59HC9; Q6P9C9;
DE   RecName: Full=AT-rich interactive domain-containing protein 3B;
DE            Short=ARID domain-containing protein 3B;
DE   AltName: Full=Bright and dead ringer protein;
DE   AltName: Full=Bright-like protein;
GN   Name=ARID3B; Synonyms=BDP, DRIL2;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARI3C_HUMAN             Reviewed;         412 AA.
AC   A6NKF2;
DE   RecName: Full=AT-rich interactive domain-containing protein 3C;
DE            Short=ARID domain-containing protein 3C;
GN   Name=ARID3C;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARI4A_HUMAN             Reviewed;        1257 AA.
AC   P29374; Q15991; Q15992; Q15993;
DE   RecName: Full=AT-rich interactive domain-containing protein 4A;
DE            Short=ARID domain-containing protein 4A;
DE   AltName: Full=Retinoblastoma-binding protein 1;
DE            Short=RBBP-1;
GN   Name=ARID4A; Synonyms=RBBP1, RBP1;
DR   GO; GO:0003677; F:DNA binding; IDA:GDB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IEA:Ensembl.
DR   GO; GO:0036124; P:histone H3-K9 trimethylation; IEA:Ensembl.
DR   GO; GO:0034773; P:histone H4-K20 trimethylation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:GDB.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ARI4B_HUMAN             Reviewed;        1312 AA.
AC   Q4LE39; A1L465; Q3MHV4; Q5HY99; Q5T2C2; Q5T2C3; Q5T2C4; Q5T2C5;
AC   Q5T2C6; Q6P600; Q86UX1; Q86WR4; Q9H915; Q9NYU3; Q9NZB6; Q9NZG4;
AC   Q9P2W4; Q9UF62; Q9Y6E1;
DE   RecName: Full=AT-rich interactive domain-containing protein 4B;
DE            Short=ARID domain-containing protein 4B;
DE   AltName: Full=180 kDa Sin3-associated polypeptide;
DE            Short=Sin3-associated polypeptide p180;
DE   AltName: Full=Breast cancer-associated antigen BRCAA1;
DE   AltName: Full=Histone deacetylase complex subunit SAP180;
DE   AltName: Full=Retinoblastoma-binding protein 1-like 1;
GN   Name=ARID4B; Synonyms=BRCAA1, RBBP1L1, RBP1L1, SAP180;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0036124; P:histone H3-K9 trimethylation; IEA:Ensembl.
DR   GO; GO:0034773; P:histone H4-K20 trimethylation; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARI5A_HUMAN             Reviewed;         594 AA.
AC   Q03989; Q6NX37;
DE   RecName: Full=AT-rich interactive domain-containing protein 5A;
DE            Short=ARID domain-containing protein 5A;
DE   AltName: Full=Modulator recognition factor 1;
DE            Short=MRF-1;
GN   Name=ARID5A; Synonyms=MRF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:GDB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:GDB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARI5B_HUMAN             Reviewed;        1188 AA.
AC   Q14865; B4DLB3; Q05DG6; Q32Q59; Q5VST4; Q6NZ42; Q7Z3M4; Q8N421;
AC   Q9H786;
DE   RecName: Full=AT-rich interactive domain-containing protein 5B;
DE            Short=ARID domain-containing protein 5B;
DE   AltName: Full=MRF1-like protein;
DE   AltName: Full=Modulator recognition factor 2;
DE            Short=MRF-2;
GN   Name=ARID5B; Synonyms=DESRT, MRF2;
DR   GO; GO:0003677; F:DNA binding; IDA:GDB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; ISS:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0060613; P:fat pad development; IEA:Ensembl.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; TAS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:GDB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARID2_HUMAN             Reviewed;        1835 AA.
AC   Q68CP9; Q15KG9; Q5EB51; Q645I3; Q6ZRY5; Q7Z3I5; Q86T28; Q96SJ6;
AC   Q9HCL5;
DE   RecName: Full=AT-rich interactive domain-containing protein 2;
DE            Short=ARID domain-containing protein 2;
DE   AltName: Full=BRG1-associated factor 200;
DE            Short=BAF200;
DE   AltName: Full=Zinc finger protein with activation potential;
DE   AltName: Full=Zipzap/p200;
GN   Name=ARID2; Synonyms=KIAA1557;
DR   GO; GO:0003677; F:DNA binding; IDA:GDB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARIP4_HUMAN             Reviewed;        1467 AA.
AC   Q9Y4B4; Q8TB57; Q9BV54;
DE   RecName: Full=Helicase ARIP4;
DE            EC=3.6.4.12;
DE   AltName: Full=Androgen receptor-interacting protein 4;
DE   AltName: Full=RAD54-like protein 2;
GN   Name=RAD54L2; Synonyms=ARIP4, KIAA0809;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003712; F:transcription cofactor activity; IEA:Ensembl.
//
ID   ARK72_HUMAN             Reviewed;         359 AA.
AC   O43488; O75749; Q5TG63;
DE   RecName: Full=Aflatoxin B1 aldehyde reductase member 2;
DE            EC=1.1.1.n11;
DE   AltName: Full=AFB1 aldehyde reductase 1;
DE            Short=AFB1-AR 1;
DE   AltName: Full=Aldoketoreductase 7;
DE   AltName: Full=Succinic semialdehyde reductase;
DE            Short=SSA reductase;
GN   Name=AKR7A2; Synonyms=AFAR, AFAR1, AKR7;
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0019119; F:phenanthrene-9,10-epoxide hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
//
ID   ARK73_HUMAN             Reviewed;         331 AA.
AC   O95154; Q86SR4; Q8IVN6; Q8N5V6; Q8TAX1; Q9NUC3;
DE   RecName: Full=Aflatoxin B1 aldehyde reductase member 3;
DE            EC=1.-.-.-;
DE   AltName: Full=AFB1 aldehyde reductase 2;
DE            Short=AFB1-AR 2;
GN   Name=AKR7A3; Synonyms=AFAR2;
DR   GO; GO:0004032; F:alditol:NADP+ 1-oxidoreductase activity; IEA:Ensembl.
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0046223; P:aflatoxin catabolic process; IEA:Ensembl.
DR   GO; GO:0006081; P:cellular aldehyde metabolic process; TAS:ProtInc.
//
ID   ARK74_HUMAN             Reviewed;         331 AA.
AC   Q8NHP1; Q5U614;
DE   RecName: Full=Aflatoxin B1 aldehyde reductase member 4;
DE            EC=1.-.-.-;
DE   AltName: Full=AFB1 aldehyde reductase 3;
DE            Short=AFB1-AR 3;
DE   AltName: Full=Aldoketoreductase 7-like;
GN   Name=AKR7L; Synonyms=AFAR3, AKR7A4;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   ARL10_HUMAN             Reviewed;         244 AA.
AC   Q8N8L6;
DE   RecName: Full=ADP-ribosylation factor-like protein 10;
GN   Name=ARL10; Synonyms=ARL10A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL11_HUMAN             Reviewed;         196 AA.
AC   Q969Q4;
DE   RecName: Full=ADP-ribosylation factor-like protein 11;
DE   AltName: Full=ADP-ribosylation factor-like tumor suppressor protein 1;
GN   Name=ARL11; Synonyms=ARLTS1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL14_HUMAN             Reviewed;         192 AA.
AC   Q8N4G2; Q9H655;
DE   RecName: Full=ADP-ribosylation factor-like protein 14;
DE   AltName: Full=ADP-ribosylation factor 7;
GN   Name=ARL14; Synonyms=ARF7;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL15_HUMAN             Reviewed;         204 AA.
AC   Q9NXU5; Q6IAD0;
DE   RecName: Full=ADP-ribosylation factor-like protein 15;
DE   AltName: Full=ADP-ribosylation factor-related protein 2;
DE            Short=ARF-related protein 2;
GN   Name=ARL15; Synonyms=ARFRP2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL16_HUMAN             Reviewed;         197 AA.
AC   Q0P5N6;
DE   RecName: Full=ADP-ribosylation factor-like protein 16;
GN   Name=ARL16;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL17_HUMAN             Reviewed;         177 AA.
AC   Q8IVW1; B0AZR6; Q59FW5; Q8N6E2; Q8TD73; Q8WW54; Q9NZD5; Q9P158;
DE   RecName: Full=ADP-ribosylation factor-like protein 17;
DE   AltName: Full=ADP-ribosylation factor 7 variant;
GN   Name=ARL17A; Synonyms=ARL17P1;
GN   and
GN   Name=ARL17B; Synonyms=ARF1P2, ARL17A; ORFNames=PRO2667;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ARL1_HUMAN              Reviewed;         181 AA.
AC   P40616; P80417; Q53XB1;
DE   RecName: Full=ADP-ribosylation factor-like protein 1;
GN   Name=ARL1;
DR   GO; GO:0008047; F:enzyme activator activity; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0031584; P:activation of phospholipase D activity; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; ISS:UniProtKB.
DR   GO; GO:0048193; P:Golgi vesicle transport; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IMP:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0009404; P:toxin metabolic process; IDA:UniProtKB.
//
ID   ARL2_HUMAN              Reviewed;         184 AA.
AC   P36404; G3V184; Q9BUK8;
DE   RecName: Full=ADP-ribosylation factor-like protein 2;
GN   Name=ARL2;
DR   GO; GO:0005525; F:GTP binding; IMP:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IMP:UniProtKB.
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IMP:GOC.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; ISS:UniProtKB.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0031113; P:regulation of microtubule polymerization; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0070830; P:tight junction assembly; ISS:UniProtKB.
DR   GO; GO:0007021; P:tubulin complex assembly; TAS:ProtInc.
//
ID   ARL3_HUMAN              Reviewed;         182 AA.
AC   P36405; B2R6C7; Q53X83; Q5JSM2;
DE   RecName: Full=ADP-ribosylation factor-like protein 3;
GN   Name=ARL3; Synonyms=ARFL3;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0042073; P:intraciliary transport; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0042461; P:photoreceptor cell development; ISS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; IMP:MGI.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IDA:UniProtKB.
//
ID   ARL4A_HUMAN             Reviewed;         200 AA.
AC   P40617; A4D119; P80418; Q49AF5;
DE   RecName: Full=ADP-ribosylation factor-like protein 4A;
GN   Name=ARL4A; Synonyms=ARL4;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL4C_HUMAN             Reviewed;         192 AA.
AC   P56559; Q53R10; Q9BVN1; Q9UQ34;
DE   RecName: Full=ADP-ribosylation factor-like protein 4C;
DE   AltName: Full=ADP-ribosylation factor-like protein 7;
DE   AltName: Full=ADP-ribosylation factor-like protein LAK;
GN   Name=ARL4C; Synonyms=ARL7;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL4D_HUMAN             Reviewed;         201 AA.
AC   P49703; B2RC59; D3DX43;
DE   RecName: Full=ADP-ribosylation factor-like protein 4D;
DE   AltName: Full=ADP-ribosylation factor-like protein 4L;
GN   Name=ARL4D; Synonyms=ARF4L;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0009306; P:protein secretion; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL5A_HUMAN             Reviewed;         179 AA.
AC   Q9Y689; Q580I5;
DE   RecName: Full=ADP-ribosylation factor-like protein 5A;
GN   Name=ARL5A; Synonyms=ARFLP5, ARL5;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL5B_HUMAN             Reviewed;         179 AA.
AC   Q96KC2;
DE   RecName: Full=ADP-ribosylation factor-like protein 5B;
DE   AltName: Full=ADP-ribosylation factor-like protein 8;
GN   Name=ARL5B; Synonyms=ARL8;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL5C_HUMAN             Reviewed;         179 AA.
AC   A6NH57;
DE   RecName: Full=Putative ADP-ribosylation factor-like protein 5C;
DE   AltName: Full=ADP-ribosylation factor-like protein 12;
GN   Name=ARL5C; Synonyms=ARL12;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL6_HUMAN              Reviewed;         186 AA.
AC   Q9H0F7; A8KA93; D3DN31;
DE   RecName: Full=ADP-ribosylation factor-like protein 6;
DE   AltName: Full=Bardet-Biedl syndrome 3 protein;
GN   Name=ARL6; Synonyms=BBS3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005543; F:phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0032402; P:melanosome transport; ISS:BHF-UCL.
DR   GO; GO:0051258; P:protein polymerization; ISS:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:UniProtKB.
//
ID   ARL8A_HUMAN             Reviewed;         186 AA.
AC   Q96BM9; B3KXD0;
DE   RecName: Full=ADP-ribosylation factor-like protein 8A;
DE   AltName: Full=ADP-ribosylation factor-like protein 10B;
DE   AltName: Full=Novel small G protein indispensable for equal chromosome segregation 2;
GN   Name=ARL8A; Synonyms=ARL10B, GIE2;
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL8B_HUMAN             Reviewed;         186 AA.
AC   Q9NVJ2;
DE   RecName: Full=ADP-ribosylation factor-like protein 8B;
DE   AltName: Full=ADP-ribosylation factor-like protein 10C;
DE   AltName: Full=Novel small G protein indispensable for equal chromosome segregation 1;
GN   Name=ARL8B; Synonyms=ARL10C, GIE1;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARL9_HUMAN              Reviewed;         187 AA.
AC   Q6T311;
DE   RecName: Full=ADP-ribosylation factor-like protein 9;
GN   Name=ARL9;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   ARLY_HUMAN              Reviewed;         464 AA.
AC   P04424; E7EMI0; E9PE48; Q6LDS5; Q96HS2;
DE   RecName: Full=Argininosuccinate lyase;
DE            Short=ASAL;
DE            EC=4.3.2.1;
DE   AltName: Full=Arginosuccinase;
GN   Name=ASL;
DR   GO; GO:0004056; F:argininosuccinate lyase activity; EXP:Reactome.
DR   GO; GO:0042450; P:arginine biosynthetic process via ornithine; IEA:InterPro.
DR   GO; GO:0006527; P:arginine catabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
//
ID   ARM10_HUMAN             Reviewed;         343 AA.
AC   Q8N2F6; A8K703; B4DWJ8; F5GX65; Q75K91; Q75MG6; Q75ML8; Q8IZC1;
AC   Q8IZC2; Q8IZC3; Q9BTM6;
DE   RecName: Full=Armadillo repeat-containing protein 10;
DE   AltName: Full=Splicing variant involved in hepatocarcinogenesis protein;
GN   Name=ARMC10; Synonyms=SVH; ORFNames=PSEC0198;
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   ARM12_HUMAN             Reviewed;         340 AA.
AC   Q5T9G4; Q8NEB2; Q96LL8;
DE   RecName: Full=Armadillo repeat-containing protein 12;
GN   Name=ARMC12; Synonyms=C6orf81;
//
ID   ARMC1_HUMAN             Reviewed;         282 AA.
AC   Q9NVT9; B4E2W7; Q9H018; Q9H820;
DE   RecName: Full=Armadillo repeat-containing protein 1;
GN   Name=ARMC1; Synonyms=ARCP;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
//
ID   ARMC2_HUMAN             Reviewed;         867 AA.
AC   Q8NEN0; A8K8Y4; Q5VVY8; Q9H0K9;
DE   RecName: Full=Armadillo repeat-containing protein 2;
GN   Name=ARMC2;
//
ID   ARMC3_HUMAN             Reviewed;         872 AA.
AC   Q5W041; A0PG76; A6NH64; B4DZL3; B7ZBN6; B7ZBN7; Q8IXS5; Q8N7B0;
AC   Q96M49;
DE   RecName: Full=Armadillo repeat-containing protein 3;
DE   AltName: Full=Beta-catenin-like protein;
DE   AltName: Full=Cancer/testis antigen 81;
DE            Short=CT81;
DE   AltName: Full=KU-CT-1;
GN   Name=ARMC3;
//
ID   ARMC4_HUMAN             Reviewed;        1044 AA.
AC   Q5T2S8; A8K906; Q9H0C0;
DE   RecName: Full=Armadillo repeat-containing protein 4;
GN   Name=ARMC4;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   ARMC5_HUMAN             Reviewed;         935 AA.
AC   Q96C12; Q86WM9; Q9H7P8; Q9H925;
DE   RecName: Full=Armadillo repeat-containing protein 5;
GN   Name=ARMC5;
//
ID   ARMC6_HUMAN             Reviewed;         501 AA.
AC   Q6NXE6; B4DI98; O94999; Q9BTH5;
DE   RecName: Full=Armadillo repeat-containing protein 6;
GN   Name=ARMC6;
//
ID   ARMC7_HUMAN             Reviewed;         198 AA.
AC   Q9H6L4;
DE   RecName: Full=Armadillo repeat-containing protein 7;
GN   Name=ARMC7;
//
ID   ARMC8_HUMAN             Reviewed;         673 AA.
AC   Q8IUR7; A8K0L2; B7Z441; B7Z453; D3DNE6; F5GWK4; Q6PIL2; Q96D19;
AC   Q96HZ5; Q9NV02; Q9NV94; Q9Y4R9;
DE   RecName: Full=Armadillo repeat-containing protein 8;
GN   Name=ARMC8; ORFNames=S863-2;
//
ID   ARMC9_HUMAN             Reviewed;         817 AA.
AC   Q7Z3E5; Q53TI3; Q6P162; Q7L594; Q86WG2; Q96JF9; Q9H9R8;
DE   RecName: Full=LisH domain-containing protein ARMC9;
DE   AltName: Full=Melanoma/melanocyte-specific tumor antigen KU-MEL-1;
DE   AltName: Full=NS21;
GN   Name=ARMC9; Synonyms=KIAA1868;
//
ID   ARMS2_HUMAN             Reviewed;         107 AA.
AC   P0C7Q2; B2Y7I5;
DE   RecName: Full=Age-related maculopathy susceptibility protein 2;
GN   Name=ARMS2;
DR   GO; GO:0001895; P:retina homeostasis; IMP:BHF-UCL.
//
ID   ARMX1_HUMAN             Reviewed;         453 AA.
AC   Q9P291; Q53HK2; Q9H2Q0;
DE   RecName: Full=Armadillo repeat-containing X-linked protein 1;
DE   AltName: Full=ARM protein lost in epithelial cancers on chromosome X 1;
DE            Short=Protein ALEX1;
GN   Name=ARMCX1; Synonyms=ALEX1; ORFNames=AD032;
//
ID   ARMX2_HUMAN             Reviewed;         632 AA.
AC   Q7L311; O60267; Q5H9D9;
DE   RecName: Full=Armadillo repeat-containing X-linked protein 2;
DE   AltName: Full=ARM protein lost in epithelial cancers on chromosome X 2;
DE            Short=Protein ALEX2;
GN   Name=ARMCX2; Synonyms=ALEX2, KIAA0512;
//
ID   ARMX3_HUMAN             Reviewed;         379 AA.
AC   Q9UH62; Q53HC6; Q7LCF5; Q9NPE4;
DE   RecName: Full=Armadillo repeat-containing X-linked protein 3;
DE   AltName: Full=ARM protein lost in epithelial cancers on chromosome X 3;
DE            Short=Protein ALEX3;
GN   Name=ARMCX3; Synonyms=ALEX3; ORFNames=BM-017, UNQ2517/PRO6007;
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   ARMX4_HUMAN             Reviewed;         360 AA.
AC   Q5H9R4; A8K928; B3KXA4; Q5H9K8; Q8N8D6;
DE   RecName: Full=Armadillo repeat-containing X-linked protein 4;
GN   Name=ARMCX4;
//
ID   ARMX5_HUMAN             Reviewed;         558 AA.
AC   Q6P1M9; B3KU88; D3DX99; Q68DB4; Q9BVZ3; Q9H969;
DE   RecName: Full=Armadillo repeat-containing X-linked protein 5;
GN   Name=ARMCX5;
//
ID   ARMX6_HUMAN             Reviewed;         300 AA.
AC   Q7L4S7; Q9NWJ3;
DE   RecName: Full=Protein ARMCX6;
GN   Name=ARMCX6;
//
ID   ARNT2_HUMAN             Reviewed;         717 AA.
AC   Q9HBZ2; B4DIS7; O15024; Q8IYC2;
DE   RecName: Full=Aryl hydrocarbon receptor nuclear translocator 2;
DE            Short=ARNT protein 2;
DE   AltName: Full=Class E basic helix-loop-helix protein 1;
DE            Short=bHLHe1;
GN   Name=ARNT2; Synonyms=BHLHE1, KIAA0307;
DR   GO; GO:0017162; F:aryl hydrocarbon receptor binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARNT_HUMAN              Reviewed;         789 AA.
AC   P27540; C4AMA1; Q5QP39; Q8NDC7;
DE   RecName: Full=Aryl hydrocarbon receptor nuclear translocator;
DE            Short=ARNT protein;
DE   AltName: Full=Class E basic helix-loop-helix protein 2;
DE            Short=bHLHe2;
DE   AltName: Full=Dioxin receptor, nuclear translocator;
DE   AltName: Full=Hypoxia-inducible factor 1-beta;
DE            Short=HIF-1-beta;
DE            Short=HIF1-beta;
GN   Name=ARNT; Synonyms=BHLHE2;
DR   GO; GO:0004874; F:aryl hydrocarbon receptor activity; IEA:Ensembl.
DR   GO; GO:0017162; F:aryl hydrocarbon receptor binding; IPI:BHF-UCL.
DR   GO; GO:0035326; F:enhancer binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IC:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IC:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IC:BHF-UCL.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IC:BHF-UCL.
DR   GO; GO:0046886; P:positive regulation of hormone biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   AROS_HUMAN              Reviewed;         136 AA.
AC   Q86WX3; B0QY96; Q5JZA1;
DE   RecName: Full=Active regulator of SIRT1;
DE   AltName: Full=40S ribosomal protein S19-binding protein 1;
DE            Short=RPS19-binding protein 1;
DE            Short=S19BP;
GN   Name=RPS19BP1; Synonyms=AROS;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ARP10_HUMAN             Reviewed;         417 AA.
AC   Q9NZ32; Q9H9Y5; Q9NWY2;
DE   RecName: Full=Actin-related protein 10;
DE   AltName: Full=Actin-related protein 11;
DE            Short=hARP11;
GN   Name=ACTR10; Synonyms=ACTR11, ARP11;
DR   GO; GO:0007018; P:microtubule-based movement; IEA:Ensembl.
//
ID   ARP19_HUMAN             Reviewed;         112 AA.
AC   P56211; B2R497; Q6IAM2; Q86TA6; Q9UD70;
DE   RecName: Full=cAMP-regulated phosphoprotein 19;
DE            Short=ARPP-19;
GN   Name=ARPP19;
DR   GO; GO:0019212; F:phosphatase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; IDA:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; NAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; ISS:GOC.
//
ID   ARP21_HUMAN             Reviewed;         812 AA.
AC   Q9UBL0; B4DG96; Q49AK3; Q49AS6; Q4G0V4; Q6NYC3; Q86V31; Q9UF93;
DE   RecName: Full=cAMP-regulated phosphoprotein 21;
DE            Short=ARPP-21;
DE   AltName: Full=Thymocyte cAMP-regulated phosphoprotein;
GN   Name=ARPP21; Synonyms=TARPP;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
//
ID   ARP2_HUMAN              Reviewed;         394 AA.
AC   P61160; B2RCP5; D6W5F4; E9PF41; O15142; Q96C82;
DE   RecName: Full=Actin-related protein 2;
DE   AltName: Full=Actin-like protein 2;
GN   Name=ACTR2; Synonyms=ARP2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0008356; P:asymmetric cell division; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0016482; P:cytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0033206; P:meiotic cytokinesis; IEA:Ensembl.
DR   GO; GO:0051653; P:spindle localization; IEA:Ensembl.
//
ID   ARP3B_HUMAN             Reviewed;         418 AA.
AC   Q9P1U1; A8MTG1; B4DFW4; Q7Z526; Q96BT2;
DE   RecName: Full=Actin-related protein 3B;
DE   AltName: Full=ARP3-beta;
DE   AltName: Full=Actin-like protein 3B;
DE   AltName: Full=Actin-related protein ARP4;
GN   Name=ACTR3B; Synonyms=ARP11, ARP4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   ARP3C_HUMAN             Reviewed;         210 AA.
AC   Q9C0K3; Q5CZI4;
DE   RecName: Full=Actin-related protein 3C;
DE   AltName: Full=Actin-related protein 11;
DE   Flags: Precursor;
GN   Name=ACTR3C; Synonyms=ARP11;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   ARP3_HUMAN              Reviewed;         418 AA.
AC   P61158; P32391; Q53QM2;
DE   RecName: Full=Actin-related protein 3;
DE   AltName: Full=Actin-like protein 3;
GN   Name=ACTR3; Synonyms=ARP3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008356; P:asymmetric cell division; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0033206; P:meiotic cytokinesis; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IEA:Ensembl.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0043519; P:regulation of myosin II filament organization; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0051653; P:spindle localization; IEA:Ensembl.
//
ID   ARP5L_HUMAN             Reviewed;         153 AA.
AC   Q9BPX5; Q7Z523;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 5-like protein;
DE   AltName: Full=Arp2/3 complex 16 kDa subunit 2;
DE            Short=ARC16-2;
GN   Name=ARPC5L;
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
//
ID   ARP5_HUMAN              Reviewed;         607 AA.
AC   Q9H9F9; Q86WF7; Q8IUY5; Q8N724; Q9BRN0; Q9BVB7;
DE   RecName: Full=Actin-related protein 5;
DE            Short=hARP5;
DE   AltName: Full=Sarcoma antigen NY-SAR-16;
GN   Name=ACTR5; Synonyms=ARP5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0070914; P:UV-damage excision repair; IMP:UniProtKB.
//
ID   ARP6_HUMAN              Reviewed;         396 AA.
AC   Q9GZN1; B3KW37; B4DLG9; Q53GH2; Q9BY39; Q9H8H6;
DE   RecName: Full=Actin-related protein 6;
DE            Short=hArp6;
DE   AltName: Full=hARPX;
GN   Name=ACTR6; ORFNames=CDA12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ARP8_HUMAN              Reviewed;         624 AA.
AC   Q9H981; B3KSW7; Q8N566; Q9H663;
DE   RecName: Full=Actin-related protein 8;
DE            Short=hArp8;
DE   AltName: Full=INO80 complex subunit N;
GN   Name=ACTR8; Synonyms=ARP8, INO80N;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARPC2_HUMAN             Reviewed;         300 AA.
AC   O15144; Q92801; Q9P1D4;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 2;
DE   AltName: Full=Arp2/3 complex 34 kDa subunit;
DE            Short=p34-ARC;
GN   Name=ARPC2; Synonyms=ARC34; ORFNames=PRO2446;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IMP:UniProt.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IEA:Ensembl.
//
ID   ARPC3_HUMAN             Reviewed;         178 AA.
AC   O15145; O00554;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 3;
DE   AltName: Full=Arp2/3 complex 21 kDa subunit;
DE            Short=p21-ARC;
GN   Name=ARPC3; Synonyms=ARC21;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   ARPC4_HUMAN             Reviewed;         168 AA.
AC   P59998; C9JWM7; E7ETI0; F6TTL5; O15509; Q6P0W5; Q96QJ3;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 4;
DE   AltName: Full=Arp2/3 complex 20 kDa subunit;
DE            Short=p20-ARC;
GN   Name=ARPC4; Synonyms=ARC20;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:InterPro.
DR   GO; GO:0045010; P:actin nucleation; NAS:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   ARPC5_HUMAN             Reviewed;         151 AA.
AC   O15511; A6NEC4; Q6PG42;
DE   RecName: Full=Actin-related protein 2/3 complex subunit 5;
DE   AltName: Full=Arp2/3 complex 16 kDa subunit;
DE            Short=p16-ARC;
GN   Name=ARPC5; Synonyms=ARC16;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
//
ID   ARPIN_HUMAN             Reviewed;         226 AA.
AC   Q7Z6K5; E2QRD5;
DE   RecName: Full=Arpin;
DE   AltName: Full=Arp2/3 inhibition protein;
GN   Name=ARPIN; Synonyms=C15orf38;
DR   GO; GO:0033058; P:directional locomotion; IMP:UniProtKB.
DR   GO; GO:0051126; P:negative regulation of actin nucleation; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:2000393; P:negative regulation of lamellipodium morphogenesis; IMP:UniProtKB.
//
ID   ARRB1_HUMAN             Reviewed;         418 AA.
AC   P49407; B6V9G8; O75625; O75630; Q2PP20; Q9BTK8;
DE   RecName: Full=Beta-arrestin-1;
DE   AltName: Full=Arrestin beta-1;
GN   Name=ARRB1; Synonyms=ARR1;
DR   GO; GO:0031701; F:angiotensin receptor binding; IPI:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IMP:UniProtKB.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0042699; P:follicle-stimulating hormone signaling pathway; IEA:Ensembl.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:UniProtKB.
DR   GO; GO:0032717; P:negative regulation of interleukin-8 production; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0007602; P:phototransduction; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IMP:GOC.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.
DR   GO; GO:0090240; P:positive regulation of histone H4 acetylation; IMP:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IMP:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0043149; P:stress fiber assembly; IMP:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IMP:UniProtKB.
//
ID   ARRB2_HUMAN             Reviewed;         409 AA.
AC   P32121; B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; Q0Z8D3; Q2PP19;
AC   Q6ICT3; Q8N7Y2; Q9UEQ6;
DE   RecName: Full=Beta-arrestin-2;
DE   AltName: Full=Arrestin beta-2;
GN   Name=ARRB2; Synonyms=ARB2, ARR2;
DR   GO; GO:0031701; F:angiotensin receptor binding; IPI:UniProtKB.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0002032; P:desensitization of G-protein coupled receptor protein signaling pathway by arrestin; IMP:UniProtKB.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0042699; P:follicle-stimulating hormone signaling pathway; IEA:Ensembl.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IDA:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045953; P:negative regulation of natural killer cell mediated cytotoxicity; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0034392; P:negative regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IGI:BHF-UCL.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IMP:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0032226; P:positive regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
//
ID   ARRC_HUMAN              Reviewed;         388 AA.
AC   P36575; B5B0B9; Q5JT23; Q5JT24; Q6IBF5; Q96EN2;
DE   RecName: Full=Arrestin-C;
DE   AltName: Full=Cone arrestin;
DE            Short=C-arrestin;
DE            Short=cArr;
DE   AltName: Full=Retinal cone arrestin-3;
DE   AltName: Full=X-arrestin;
GN   Name=ARR3; Synonyms=ARRX, CAR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   ARRD1_HUMAN             Reviewed;         433 AA.
AC   Q8N5I2;
DE   RecName: Full=Arrestin domain-containing protein 1;
GN   Name=ARRDC1;
//
ID   ARRD2_HUMAN             Reviewed;         407 AA.
AC   Q8TBH0; B2RBG9; O95895; Q6ZRV9; Q8WYG6;
DE   RecName: Full=Arrestin domain-containing protein 2;
GN   Name=ARRDC2; ORFNames=PP2703;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   ARRD3_HUMAN             Reviewed;         414 AA.
AC   Q96B67; A8K6T8; Q9P2H1;
DE   RecName: Full=Arrestin domain-containing protein 3;
DE   AltName: Full=TBP-2-like inducible membrane protein;
DE            Short=TLIMP;
GN   Name=ARRDC3; Synonyms=KIAA1376;
DR   GO; GO:0031699; F:beta-3 adrenergic receptor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060613; P:fat pad development; IEA:Ensembl.
DR   GO; GO:0031651; P:negative regulation of heat generation; IEA:Ensembl.
DR   GO; GO:0090327; P:negative regulation of locomotion involved in locomotory behavior; IEA:Ensembl.
DR   GO; GO:0044252; P:negative regulation of multicellular organismal metabolic process; IEA:Ensembl.
DR   GO; GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IPI:MGI.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
//
ID   ARRD4_HUMAN             Reviewed;         418 AA.
AC   Q8NCT1; Q6NSI9;
DE   RecName: Full=Arrestin domain-containing protein 4;
GN   Name=ARRDC4;
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IPI:MGI.
//
ID   ARRD5_HUMAN             Reviewed;         342 AA.
AC   A6NEK1;
DE   RecName: Full=Arrestin domain-containing protein 5;
GN   Name=ARRDC5;
//
ID   ARRS_HUMAN              Reviewed;         405 AA.
AC   P10523; A0FDN6; Q53SV3; Q99858;
DE   RecName: Full=S-arrestin;
DE   AltName: Full=48 kDa protein;
DE   AltName: Full=Retinal S-antigen;
DE            Short=S-AG;
DE   AltName: Full=Rod photoreceptor arrestin;
GN   Name=SAG;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   ARSA_HUMAN              Reviewed;         507 AA.
AC   P15289; B2RCA6; B7XD04; F8WCC8; Q6ICI5; Q96CJ0;
DE   RecName: Full=Arylsulfatase A;
DE            Short=ASA;
DE            EC=3.1.6.8;
DE   AltName: Full=Cerebroside-sulfatase;
DE   Contains:
DE     RecName: Full=Arylsulfatase A component B;
DE   Contains:
DE     RecName: Full=Arylsulfatase A component C;
DE   Flags: Precursor;
GN   Name=ARSA;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0004098; F:cerebroside-sulfatase activity; TAS:Reactome.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IDA:MGI.
DR   GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSB_HUMAN              Reviewed;         533 AA.
AC   P15848; B2RC20; Q8N322; Q9UDI9;
DE   RecName: Full=Arylsulfatase B;
DE            Short=ASB;
DE            EC=3.1.6.12;
DE   AltName: Full=N-acetylgalactosamine-4-sulfatase;
DE            Short=G4S;
DE   Flags: Precursor;
GN   Name=ARSB;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003943; F:N-acetylgalactosamine-4-sulfatase activity; TAS:Reactome.
DR   GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0007041; P:lysosomal transport; TAS:ProtInc.
DR   GO; GO:0007040; P:lysosome organization; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSD_HUMAN              Reviewed;         593 AA.
AC   P51689; Q9UHJ8;
DE   RecName: Full=Arylsulfatase D;
DE            Short=ASD;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=ARSD;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSE_HUMAN              Reviewed;         589 AA.
AC   P51690; Q53FT2; Q53FU8;
DE   RecName: Full=Arylsulfatase E;
DE            Short=ASE;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=ARSE;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSF_HUMAN              Reviewed;         590 AA.
AC   P54793; Q8TCC5;
DE   RecName: Full=Arylsulfatase F;
DE            Short=ASF;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=ARSF;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSG_HUMAN              Reviewed;         525 AA.
AC   Q96EG1; Q6UXF2; Q9Y2K4;
DE   RecName: Full=Arylsulfatase G;
DE            Short=ASG;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=ARSG; Synonyms=KIAA1001; ORFNames=UNQ839/PRO1777;
DR   GO; GO:0004065; F:arylsulfatase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   ARSH_HUMAN              Reviewed;         562 AA.
AC   Q5FYA8;
DE   RecName: Full=Arylsulfatase H;
DE            Short=ASH;
DE            EC=3.1.6.-;
GN   Name=ARSH;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSI_HUMAN              Reviewed;         569 AA.
AC   Q5FYB1; A1L3B0; B3KV22; B7XD03;
DE   RecName: Full=Arylsulfatase I;
DE            Short=ASI;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=ARSI;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSJ_HUMAN              Reviewed;         599 AA.
AC   Q5FYB0; A2RUG0; B7ZM45; Q1HA39; Q5FWE4; Q6UWT9;
DE   RecName: Full=Arylsulfatase J;
DE            Short=ASJ;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=ARSJ; ORFNames=UNQ372/PRO708;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARSK_HUMAN              Reviewed;         536 AA.
AC   Q6UWY0; A2BDE3; B4E1I4; Q3ZCW3; Q8N3Q8;
DE   RecName: Full=Arylsulfatase K;
DE            Short=ASK;
DE            EC=3.1.6.-;
DE   AltName: Full=Telethon sulfatase;
DE   Flags: Precursor;
GN   Name=ARSK; Synonyms=TSULF; ORFNames=UNQ630/PRO1246;
DR   GO; GO:0004065; F:arylsulfatase activity; TAS:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ARTN_HUMAN              Reviewed;         220 AA.
AC   Q5T4W7; D3DPY1; D3DPY3; O95441; O96030; Q6P6A3;
DE   RecName: Full=Artemin;
DE   AltName: Full=Enovin;
DE   AltName: Full=Neublastin;
DE   Flags: Precursor;
GN   Name=ARTN; Synonyms=EVN;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0097021; P:lymphocyte migration into lymphoid organs; IEA:Ensembl.
DR   GO; GO:0007405; P:neuroblast proliferation; TAS:ProtInc.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0061146; P:Peyer's patch morphogenesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ARV1_HUMAN              Reviewed;         271 AA.
AC   Q9H2C2; A8KAI4; Q5VSN7; Q5VSN8; Q5VSN9; Q5VSP0; Q5VSP2; Q9H2H2;
AC   Q9H5V6; Q9UFF5;
DE   RecName: Full=Protein ARV1;
DE            Short=hARV1;
GN   Name=ARV1; ORFNames=HT035;
DR   GO; GO:0008206; P:bile acid metabolic process; IEA:Ensembl.
DR   GO; GO:0030301; P:cholesterol transport; IEA:Ensembl.
DR   GO; GO:0090181; P:regulation of cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
//
ID   ARVC_HUMAN              Reviewed;         962 AA.
AC   O00192; B7WNV2;
DE   RecName: Full=Armadillo repeat protein deleted in velo-cardio-facial syndrome;
GN   Name=ARVCF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   ARX_HUMAN               Reviewed;         562 AA.
AC   Q96QS3;
DE   RecName: Full=Homeobox protein ARX;
DE   AltName: Full=Aristaless-related homeobox;
GN   Name=ARX;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0021853; P:cerebral cortex GABAergic interneuron migration; IEA:Ensembl.
DR   GO; GO:0021800; P:cerebral cortex tangential migration; IEA:Ensembl.
DR   GO; GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IEA:Ensembl.
DR   GO; GO:0072148; P:epithelial cell fate commitment; IEA:Ensembl.
DR   GO; GO:0021759; P:globus pallidus development; IEA:Ensembl.
DR   GO; GO:0044241; P:lipid digestion; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ARY1_HUMAN              Reviewed;         290 AA.
AC   P18440; A8K4E7; O15159; O15300; Q546N1; Q96TE9;
DE   RecName: Full=Arylamine N-acetyltransferase 1;
DE            EC=2.3.1.5;
DE   AltName: Full=Arylamide acetylase 1;
DE   AltName: Full=Monomorphic arylamine N-acetyltransferase;
DE            Short=MNAT;
DE   AltName: Full=N-acetyltransferase type 1;
DE            Short=NAT-1;
GN   Name=NAT1; Synonyms=AAC1;
DR   GO; GO:0004060; F:arylamine N-acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ARY2_HUMAN              Reviewed;         290 AA.
AC   P11245; O43637; O60654; O60655; Q13146; Q16697; Q2MLE4; Q2MLF5;
AC   Q2MLG8; Q2MLJ6; Q2MLK4; Q2MLK6; Q2MLN7; Q6LET4; Q86XS0; Q86XS1;
AC   Q96KY8; Q96T64; Q96T65; Q9H220;
DE   RecName: Full=Arylamine N-acetyltransferase 2;
DE            EC=2.3.1.5;
DE   AltName: Full=Arylamide acetylase 2;
DE   AltName: Full=N-acetyltransferase type 2;
DE            Short=NAT-2;
DE   AltName: Full=Polymorphic arylamine N-acetyltransferase;
DE            Short=PNAT;
GN   Name=NAT2; Synonyms=AAC2;
DR   GO; GO:0004060; F:arylamine N-acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   AS3MT_HUMAN             Reviewed;         375 AA.
AC   Q9HBK9; A6NP79; Q0VDK3; Q0VDK4; Q5PZ02;
DE   RecName: Full=Arsenite methyltransferase;
DE            EC=2.1.1.137;
DE   AltName: Full=Methylarsonite methyltransferase;
DE   AltName: Full=S-adenosyl-L-methionine:arsenic(III) methyltransferase;
GN   Name=AS3MT; Synonyms=CYT19;
DR   GO; GO:0030791; F:arsenite methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0030792; F:methylarsonite methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0018872; P:arsonoacetate metabolic process; ISS:UniProtKB.
DR   GO; GO:0009404; P:toxin metabolic process; ISS:UniProtKB.
//
ID   ASA2B_HUMAN             Reviewed;         165 AA.
AC   P0C7U1;
DE   RecName: Full=Putative inactive neutral ceramidase B;
DE   AltName: Full=ASAH2-like protein;
DE   AltName: Full=Putative inactive N-acylsphingosine amidohydrolase 2B;
DE   AltName: Full=Putative inactive non-lysosomal ceramidase B;
GN   Name=ASAH2B; Synonyms=ASAH2L;
//
ID   ASA2C_HUMAN             Reviewed;         622 AA.
AC   P0C7U2;
DE   RecName: Full=Putative neutral ceramidase C;
DE            EC=3.5.1.23;
DE   AltName: Full=N-acylsphingosine amidohydrolase 2C;
DE   AltName: Full=Non-lysosomal ceramidase C;
GN   Name=ASAH2C;
DR   GO; GO:0017040; F:ceramidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
//
ID   ASAH1_HUMAN             Reviewed;         395 AA.
AC   Q13510; E9PDS0; Q6W898; Q96AS2;
DE   RecName: Full=Acid ceramidase;
DE            Short=AC;
DE            Short=ACDase;
DE            Short=Acid CDase;
DE            EC=3.5.1.23;
DE   AltName: Full=Acylsphingosine deacylase;
DE   AltName: Full=N-acylsphingosine amidohydrolase;
DE   AltName: Full=Putative 32 kDa heart protein;
DE            Short=PHP32;
DE   Contains:
DE     RecName: Full=Acid ceramidase subunit alpha;
DE   Contains:
DE     RecName: Full=Acid ceramidase subunit beta;
DE   Flags: Precursor;
GN   Name=ASAH1; Synonyms=ASAH; ORFNames=HSD-33, HSD33;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0017040; F:ceramidase activity; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006672; P:ceramide metabolic process; TAS:ProtInc.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ASAH2_HUMAN             Reviewed;         780 AA.
AC   Q9NR71; Q3KNU1; Q5SNT7; Q5SZP6; Q5SZP7; Q5T1D5; Q71ME6;
DE   RecName: Full=Neutral ceramidase;
DE            Short=N-CDase;
DE            Short=NCDase;
DE            EC=3.5.1.23;
DE   AltName: Full=Acylsphingosine deacylase 2;
DE   AltName: Full=BCDase;
DE   AltName: Full=LCDase;
DE            Short=hCD;
DE   AltName: Full=N-acylsphingosine amidohydrolase 2;
DE   AltName: Full=Non-lysosomal ceramidase;
DE   Contains:
DE     RecName: Full=Neutral ceramidase soluble form;
GN   Name=ASAH2; Synonyms=HNAC1;
DR   GO; GO:0017040; F:ceramidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006672; P:ceramide metabolic process; TAS:ProtInc.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   ASAP1_HUMAN             Reviewed;        1129 AA.
AC   Q9ULH1; B2RNV3;
DE   RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1;
DE   AltName: Full=130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein;
DE   AltName: Full=ADP-ribosylation factor-directed GTPase-activating protein 1;
DE            Short=ARF GTPase-activating protein 1;
DE   AltName: Full=Development and differentiation-enhancing factor 1;
DE            Short=DEF-1;
DE            Short=Differentiation-enhancing factor 1;
DE   AltName: Full=PIP2-dependent ARF1 GAP;
GN   Name=ASAP1; Synonyms=DDEF1, KIAA1249;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   ASAP2_HUMAN             Reviewed;        1006 AA.
AC   O43150; D6W4Y8;
DE   RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2;
DE   AltName: Full=Development and differentiation-enhancing factor 2;
DE   AltName: Full=Paxillin-associated protein with ARF GAP activity 3;
DE            Short=PAG3;
DE   AltName: Full=Pyk2 C-terminus-associated protein;
DE            Short=PAP;
GN   Name=ASAP2; Synonyms=DDEF2, KIAA0400;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   ASAP3_HUMAN             Reviewed;         903 AA.
AC   Q8TDY4; B3KRW0; B4DHH4; Q6P9F4; Q86UY1; Q9NXK2;
DE   RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3;
DE   AltName: Full=Development and differentiation-enhancing factor-like 1;
DE   AltName: Full=Protein up-regulated in liver cancer 1;
GN   Name=ASAP3; Synonyms=DDEFL1, UPLC1;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0032850; P:positive regulation of ARF GTPase activity; IDA:UniProtKB.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; IMP:UniProtKB.
//
ID   ASAS1_HUMAN             Reviewed;         193 AA.
AC   Q495Z4; Q495Z5; Q495Z6;
DE   RecName: Full=Putative uncharacterized protein ASB16-AS1;
DE   AltName: Full=ASB16 antisense RNA 1;
DE   AltName: Full=ASB16 antisense gene protein 1;
GN   Name=ASB16-AS1; Synonyms=C17orf65;
//
ID   ASB10_HUMAN             Reviewed;         467 AA.
AC   Q8WXI3; A0AVH0; Q6ZUL6;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 10;
DE            Short=ASB-10;
GN   Name=ASB10;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB11_HUMAN             Reviewed;         323 AA.
AC   Q8WXH4; E9PEN1; Q3SYC4; Q7Z667;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 11;
DE            Short=ASB-11;
GN   Name=ASB11;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB12_HUMAN             Reviewed;         309 AA.
AC   Q8WXK4; J3KP57; Q2M3D5; Q52LK4; Q6ISF9; Q8N8F5;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 12;
DE            Short=ASB-12;
GN   Name=ASB12;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB14_HUMAN             Reviewed;         587 AA.
AC   A6NK59; C9JX97; Q8WXK2; Q92816;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 14;
DE            Short=ASB-14;
GN   Name=ASB14;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB13_HUMAN             Reviewed;         278 AA.
AC   Q8WXK3; A8K7Q6; D3DRR2; Q96EP7; Q9H8Z1;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 13;
DE            Short=ASB-13;
GN   Name=ASB13;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB15_HUMAN             Reviewed;         588 AA.
AC   Q8WXK1; Q3ZCP3; Q3ZCP5; Q68D37;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 15;
DE            Short=ASB-15;
GN   Name=ASB15;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB16_HUMAN             Reviewed;         453 AA.
AC   Q96NS5; B2RBC0; Q8WXK0;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 16;
DE            Short=ASB-16;
GN   Name=ASB16;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB17_HUMAN             Reviewed;         295 AA.
AC   Q8WXJ9; B1APB8; Q8N0X5;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 17;
DE            Short=ASB-17;
GN   Name=ASB17;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB18_HUMAN             Reviewed;         466 AA.
AC   Q6ZVZ8; B6ZDL7;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 18;
DE            Short=ASB-18;
GN   Name=ASB18;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB1_HUMAN              Reviewed;         335 AA.
AC   Q9Y576; A6NL50; Q4ZG29; Q9ULS4;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 1;
DE            Short=ASB-1;
GN   Name=ASB1; Synonyms=KIAA1146;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0042036; P:negative regulation of cytokine biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB2_HUMAN              Reviewed;         587 AA.
AC   Q96Q27; B2RDP9; B4E166; Q9NSU5; Q9Y567;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 2;
DE            Short=ASB-2;
GN   Name=ASB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   ASB3_HUMAN              Reviewed;         518 AA.
AC   Q9Y575; B3KPA3; D6W5B4; D6W5B5; G8JLA9; Q2TAI4; Q53TN0; Q53TN8;
AC   Q9NVZ2;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 3;
DE            Short=ASB-3;
GN   Name=ASB3;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB4_HUMAN              Reviewed;         426 AA.
AC   Q9Y574; A4D1H6; O14586; Q14D68; Q8TBT2;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 4;
DE            Short=ASB-4;
GN   Name=ASB4;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IEA:Ensembl.
//
ID   ASB5_HUMAN              Reviewed;         329 AA.
AC   Q8WWX0; Q8N7B5;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 5;
DE            Short=ASB-5;
GN   Name=ASB5;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB6_HUMAN              Reviewed;         421 AA.
AC   Q9NWX5; Q5SZB7; Q9BV15;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 6;
DE            Short=ASB-6;
GN   Name=ASB6;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB7_HUMAN              Reviewed;         318 AA.
AC   Q9H672; A8K1E5; Q6GSJ6; Q7Z4S3;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 7;
DE            Short=ASB-7;
GN   Name=ASB7;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB8_HUMAN              Reviewed;         288 AA.
AC   Q9H765; A8K1P2; Q547Q2;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 8;
DE            Short=ASB-8;
GN   Name=ASB8; ORFNames=PP14212;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ASB9_HUMAN              Reviewed;         294 AA.
AC   Q96DX5; A8K8A5; Q9BVF5; Q9NWS5; Q9Y4T3;
DE   RecName: Full=Ankyrin repeat and SOCS box protein 9;
DE            Short=ASB-9;
GN   Name=ASB9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:MGI.
//
ID   ASCC1_HUMAN             Reviewed;         400 AA.
AC   Q8N9N2; Q5SW06; Q5SW07; Q96EI8; Q9Y307;
DE   RecName: Full=Activating signal cointegrator 1 complex subunit 1;
DE   AltName: Full=ASC-1 complex subunit p50;
DE   AltName: Full=Trip4 complex subunit p50;
GN   Name=ASCC1; ORFNames=CGI-18;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASCC2_HUMAN             Reviewed;         757 AA.
AC   Q9H1I8; B7Z8E0; F5H6J9; Q4TT54; Q8TAZ0; Q9H711; Q9H9D6;
DE   RecName: Full=Activating signal cointegrator 1 complex subunit 2;
DE   AltName: Full=ASC-1 complex subunit p100;
DE   AltName: Full=Trip4 complex subunit p100;
GN   Name=ASCC2; Synonyms=ASC1P100;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASCC3_HUMAN             Reviewed;        2202 AA.
AC   Q8N3C0; E7EW23; O43738; Q4G1A0; Q5VTN2; Q9H1I9; Q9H5A2; Q9NTR0;
DE   RecName: Full=Activating signal cointegrator 1 complex subunit 3;
DE            EC=3.6.4.12;
DE   AltName: Full=ASC-1 complex subunit p200;
DE            Short=ASC1p200;
DE   AltName: Full=Helicase, ATP binding 1;
DE   AltName: Full=Trip4 complex subunit p200;
GN   Name=ASCC3; Synonyms=HELIC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASCL1_HUMAN             Reviewed;         236 AA.
AC   P50553; A8K3C4; Q9BQ30;
DE   RecName: Full=Achaete-scute homolog 1;
DE            Short=ASH-1;
DE            Short=hASH1;
DE   AltName: Full=Class A basic helix-loop-helix protein 46;
DE            Short=bHLHa46;
GN   Name=ASCL1; Synonyms=ASH1, BHLHA46, HASH1;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0061104; P:adrenal chromaffin cell differentiation; IEA:Ensembl.
DR   GO; GO:0061103; P:carotid body glomus cell differentiation; IEA:Ensembl.
DR   GO; GO:0071259; P:cellular response to magnetism; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0021892; P:cerebral cortex GABAergic interneuron differentiation; IEP:UniProtKB.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0061100; P:lung neuroendocrine cell differentiation; IEA:Ensembl.
DR   GO; GO:0050883; P:musculoskeletal movement, spinal reflex action; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007400; P:neuroblast fate determination; IEA:Ensembl.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IDA:UniProtKB.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0003358; P:noradrenergic neuron development; ISS:UniProtKB.
DR   GO; GO:0003359; P:noradrenergic neuron fate commitment; IMP:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060166; P:olfactory pit development; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0060165; P:regulation of timing of subpallium neuron differentiation; IEA:Ensembl.
DR   GO; GO:0070849; P:response to epidermal growth factor; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEP:UniProtKB.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021530; P:spinal cord oligodendrocyte cell fate specification; IEA:Ensembl.
DR   GO; GO:0061102; P:stomach neuroendocrine cell differentiation; IEA:Ensembl.
DR   GO; GO:0060163; P:subpallium neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060579; P:ventral spinal cord interneuron fate commitment; ISS:UniProtKB.
DR   GO; GO:0021750; P:vestibular nucleus development; IEA:Ensembl.
//
ID   ASCL2_HUMAN             Reviewed;         193 AA.
AC   Q99929; Q6PEY9; Q9UM68;
DE   RecName: Full=Achaete-scute homolog 2;
DE            Short=ASH-2;
DE            Short=hASH2;
DE   AltName: Full=Class A basic helix-loop-helix protein 45;
DE            Short=bHLHa45;
DE   AltName: Full=Mash2;
GN   Name=ASCL2; Synonyms=BHLHA45, HASH2;
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0010626; P:negative regulation of Schwann cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0001890; P:placenta development; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0060708; P:spongiotrophoblast differentiation; IEA:Ensembl.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   ASCL3_HUMAN             Reviewed;         180 AA.
AC   Q9NQ33; Q8WYQ6;
DE   RecName: Full=Achaete-scute homolog 3;
DE            Short=ASH-3;
DE            Short=hASH3;
DE   AltName: Full=Class A basic helix-loop-helix protein 42;
DE            Short=bHLHa42;
DE   AltName: Full=bHLH transcriptional regulator Sgn-1;
GN   Name=ASCL3; Synonyms=BHLHA42, HASH3, SGN1;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:UniProtKB.
//
ID   ASCL5_HUMAN             Reviewed;         278 AA.
AC   Q7RTU5;
DE   RecName: Full=Achaete-scute homolog 5;
DE            Short=ASH-5;
DE            Short=hASH5;
DE   AltName: Full=Class A basic helix-loop-helix protein 47;
DE            Short=bHLHa47;
GN   Name=ASCL5; Synonyms=BHLHA47;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASCL4_HUMAN             Reviewed;         172 AA.
AC   Q6XD76; Q7RTS2;
DE   RecName: Full=Achaete-scute homolog 4;
DE            Short=ASH-4;
DE            Short=hASH4;
DE   AltName: Full=Achaete-scute-like protein 4;
DE   AltName: Full=Class A basic helix-loop-helix protein 44;
DE            Short=bHLHa44;
GN   Name=ASCL4; Synonyms=BHLHA44, HASH4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0043588; P:skin development; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASC_HUMAN               Reviewed;         195 AA.
AC   Q9ULZ3; Q96D12; Q9BSZ5; Q9HBD0; Q9NXJ8;
DE   RecName: Full=Apoptosis-associated speck-like protein containing a CARD;
DE            Short=hASC;
DE   AltName: Full=Caspase recruitment domain-containing protein 5;
DE   AltName: Full=PYD and CARD domain-containing protein;
DE   AltName: Full=Target of methylation-induced silencing 1;
GN   Name=PYCARD; Synonyms=ASC, CARD5, TMS1;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0032090; F:Pyrin domain binding; IPI:HGNC.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0002218; P:activation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IMP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032611; P:interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0044351; P:macropinocytosis; ISS:UniProtKB.
DR   GO; GO:0001773; P:myeloid dendritic cell activation; IMP:UniProtKB.
DR   GO; GO:0002277; P:myeloid dendritic cell activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0032688; P:negative regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0002821; P:positive regulation of adaptive immune response; IMP:UniProtKB.
DR   GO; GO:0002588; P:positive regulation of antigen processing and presentation of peptide antigen via MHC class II; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IMP:UniProtKB.
DR   GO; GO:2001056; P:positive regulation of cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.
DR   GO; GO:2001181; P:positive regulation of interleukin-10 secretion; IMP:UniProtKB.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.
DR   GO; GO:2000778; P:positive regulation of interleukin-6 secretion; IMP:UniProtKB.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IMP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IMP:UniProtKB.
DR   GO; GO:2000406; P:positive regulation of T cell migration; ISS:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:2001242; P:regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0010803; P:regulation of tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:HGNC.
//
ID   ASF1A_HUMAN             Reviewed;         204 AA.
AC   Q9Y294; Q6IA08; Q9P014;
DE   RecName: Full=Histone chaperone ASF1A;
DE   AltName: Full=Anti-silencing function protein 1 homolog A;
DE            Short=hAsf1;
DE            Short=hAsf1a;
DE   AltName: Full=CCG1-interacting factor A;
DE            Short=CIA;
DE            Short=hCIA;
GN   Name=ASF1A; ORFNames=CGI-98, HSPC146;
DR   GO; GO:0003682; F:chromatin binding; NAS:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IDA:MGI.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0031936; P:negative regulation of chromatin silencing; NAS:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:MGI.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASF1B_HUMAN             Reviewed;         202 AA.
AC   Q9NVP2; Q53G51; Q9NVZ0;
DE   RecName: Full=Histone chaperone ASF1B;
DE   AltName: Full=Anti-silencing function protein 1 homolog B;
DE            Short=hAsf1;
DE            Short=hAsf1b;
DE   AltName: Full=CCG1-interacting factor A-II;
DE            Short=CIA-II;
DE            Short=hCIA-II;
GN   Name=ASF1B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASGL1_HUMAN             Reviewed;         308 AA.
AC   Q7L266; B2R7Q0; Q567Q4; Q6P1P0; Q8NI34; Q9H6F7;
DE   RecName: Full=Isoaspartyl peptidase/L-asparaginase;
DE            EC=3.4.19.5;
DE            EC=3.5.1.1;
DE   AltName: Full=Asparaginase-like protein 1;
DE   AltName: Full=Beta-aspartyl-peptidase;
DE   AltName: Full=Isoaspartyl dipeptidase;
DE   AltName: Full=L-asparagine amidohydrolase;
DE   Contains:
DE     RecName: Full=Isoaspartyl peptidase/L-asparaginase alpha chain;
DE   Contains:
DE     RecName: Full=Isoaspartyl peptidase/L-asparaginase beta chain;
DE   Flags: Precursor;
GN   Name=ASRGL1; Synonyms=ALP, CRASH;
DR   GO; GO:0004067; F:asparaginase activity; IDA:UniProtKB.
DR   GO; GO:0008798; F:beta-aspartyl-peptidase activity; IDA:UniProtKB.
DR   GO; GO:0033345; P:asparagine catabolic process via L-aspartate; IDA:UniProtKB.
//
ID   ASGR1_HUMAN             Reviewed;         291 AA.
AC   P07306; I3L1X1;
DE   RecName: Full=Asialoglycoprotein receptor 1;
DE            Short=ASGP-R 1;
DE            Short=ASGPR 1;
DE   AltName: Full=C-type lectin domain family 4 member H1;
DE   AltName: Full=Hepatic lectin H1;
DE            Short=HL-1;
GN   Name=ASGR1; Synonyms=CLEC4H1;
DR   GO; GO:0004873; F:asialoglycoprotein receptor activity; TAS:ProtInc.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
//
ID   ASGR2_HUMAN             Reviewed;         311 AA.
AC   P07307; A6NLV8; A8MT12; D3DTM9; D3DTN0; O00448; Q03969;
DE   RecName: Full=Asialoglycoprotein receptor 2;
DE            Short=ASGP-R 2;
DE            Short=ASGPR 2;
DE   AltName: Full=C-type lectin domain family 4 member H2;
DE   AltName: Full=Hepatic lectin H2;
DE            Short=HL-2;
GN   Name=ASGR2; Synonyms=CLEC4H2;
DR   GO; GO:0004873; F:asialoglycoprotein receptor activity; TAS:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0055088; P:lipid homeostasis; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:GOC.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
//
ID   ASH1L_HUMAN             Reviewed;        2969 AA.
AC   Q9NR48; Q59GP1; Q5T714; Q5T715; Q9P2C7;
DE   RecName: Full=Histone-lysine N-methyltransferase ASH1L;
DE            EC=2.1.1.43;
DE   AltName: Full=ASH1-like protein;
DE            Short=huASH1;
DE   AltName: Full=Absent small and homeotic disks protein 1 homolog;
DE   AltName: Full=Lysine N-methyltransferase 2H;
GN   Name=ASH1L; Synonyms=KIAA1420, KMT2H;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006323; P:DNA packaging; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ASH2L_HUMAN             Reviewed;         628 AA.
AC   Q9UBL3; A8K7C3; D3DSW9; O60659; O60660; Q96B62;
DE   RecName: Full=Set1/Ash2 histone methyltransferase complex subunit ASH2;
DE   AltName: Full=ASH2-like protein;
GN   Name=ASH2L; Synonyms=ASH2L1;
DR   GO; GO:0003677; F:DNA binding; IC:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   ASHWN_HUMAN             Reviewed;         232 AA.
AC   Q9BVC5; B3KXN3; B4E2G9;
DE   RecName: Full=Ashwin;
GN   Name=C2orf49;
DR   GO; GO:0048598; P:embryonic morphogenesis; IEA:InterPro.
//
ID   ASIC1_HUMAN             Reviewed;         528 AA.
AC   P78348; A3KN86; E5KBL7; P78349; Q96CV2;
DE   RecName: Full=Acid-sensing ion channel 1;
DE            Short=ASIC1;
DE   AltName: Full=Amiloride-sensitive cation channel 2, neuronal;
DE   AltName: Full=Brain sodium channel 2;
DE            Short=BNaC2;
GN   Name=ASIC1; Synonyms=ACCN2, BNAC2;
DR   GuidetoPHARMACOLOGY; 684; -.
DR   GO; GO:0044736; F:acid-sensing ion channel activity; IDA:UniProtKB.
DR   GO; GO:0022839; F:ion gated channel activity; IEA:Ensembl.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0071467; P:cellular response to pH; IDA:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0046929; P:negative regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; ISS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; TAS:ProtInc.
DR   GO; GO:0050915; P:sensory perception of sour taste; IMP:UniProt.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ASIC2_HUMAN             Reviewed;         512 AA.
AC   Q16515; E9PBX2; Q13553; Q6DJU1; Q8N3E2;
DE   RecName: Full=Acid-sensing ion channel 2;
DE            Short=ASIC2;
DE   AltName: Full=Amiloride-sensitive brain sodium channel;
DE   AltName: Full=Amiloride-sensitive cation channel 1, neuronal;
DE   AltName: Full=Amiloride-sensitive cation channel neuronal 1;
DE   AltName: Full=Brain sodium channel 1;
DE            Short=BNC1;
DE            Short=BNaC1;
DE   AltName: Full=Mammalian degenerin homolog;
GN   Name=ASIC2; Synonyms=ACCN, ACCN1, BNAC1, MDEG;
DR   GuidetoPHARMACOLOGY; 685; -.
DR   GO; GO:0022839; F:ion gated channel activity; IEA:Ensembl.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0050974; P:detection of mechanical stimulus involved in sensory perception; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0015672; P:monovalent inorganic cation transport; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0007602; P:phototransduction; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0035418; P:protein localization to synapse; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0003026; P:regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback; IEA:Ensembl.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0050915; P:sensory perception of sour taste; IMP:UniProt.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ASIC3_HUMAN             Reviewed;         531 AA.
AC   Q9UHC3; B2R9V0; O60263; O75906; Q59FN9; Q9UER8; Q9UHC4;
DE   RecName: Full=Acid-sensing ion channel 3;
DE            Short=ASIC3;
DE            Short=hASIC3;
DE   AltName: Full=Amiloride-sensitive cation channel 3;
DE   AltName: Full=Neuronal amiloride-sensitive cation channel 3;
DE   AltName: Full=Testis sodium channel 1;
DE            Short=hTNaC1;
GN   Name=ASIC3; Synonyms=ACCN3, SLNAC1, TNAC1;
DR   GuidetoPHARMACOLOGY; 686; -.
DR   GO; GO:0005261; F:cation channel activity; TAS:ProtInc.
DR   GO; GO:0042931; F:enterobactin transporter activity; IEA:Ensembl.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0005272; F:sodium channel activity; TAS:ProtInc.
DR   GO; GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0050915; P:sensory perception of sour taste; IMP:UniProt.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ASIC4_HUMAN             Reviewed;         647 AA.
AC   Q96FT7; Q53SB7; Q6GMS1; Q6PIN9; Q9NQA4;
DE   RecName: Full=Acid-sensing ion channel 4;
DE            Short=ASIC4;
DE   AltName: Full=Amiloride-sensitive cation channel 4;
DE   AltName: Full=Amiloride-sensitive cation channel 4, pituitary;
GN   Name=ASIC4; Synonyms=ACCN4;
DR   GO; GO:0005216; F:ion channel activity; TAS:ProtInc.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0015081; F:sodium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ASIC5_HUMAN             Reviewed;         505 AA.
AC   Q9NY37;
DE   RecName: Full=Acid-sensing ion channel 5;
DE            Short=ASIC5;
DE   AltName: Full=Amiloride-sensitive cation channel 5;
DE   AltName: Full=Human intestine Na(+) channel;
DE            Short=HINaC;
GN   Name=ASIC5; Synonyms=ACCN5, HINAC;
DR   GO; GO:0015252; F:hydrogen ion channel activity; IEA:Ensembl.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ASIP_HUMAN              Reviewed;         132 AA.
AC   P42127; Q3SXL2;
DE   RecName: Full=Agouti-signaling protein;
DE            Short=ASP;
DE   AltName: Full=Agouti switch protein;
DE   Flags: Precursor;
GN   Name=ASIP; Synonyms=AGTI, AGTIL, ASP;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008343; P:adult feeding behavior; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0071514; P:genetic imprinting; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:InterPro.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032438; P:melanosome organization; IEA:Ensembl.
DR   GO; GO:0032402; P:melanosome transport; IEA:Ensembl.
DR   GO; GO:0040030; P:regulation of molecular function, epigenetic; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ASM3A_HUMAN             Reviewed;         453 AA.
AC   Q92484; B7Z729; Q8WV13;
DE   RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3a;
DE            Short=ASM-like phosphodiesterase 3a;
DE            EC=3.1.4.-;
DE   Flags: Precursor;
GN   Name=SMPDL3A; Synonyms=ASML3A;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0006685; P:sphingomyelin catabolic process; IEA:InterPro.
//
ID   ASM3B_HUMAN             Reviewed;         455 AA.
AC   Q92485; B7ZB35; Q5T0Z0; Q96CB7;
DE   RecName: Full=Acid sphingomyelinase-like phosphodiesterase 3b;
DE            Short=ASM-like phosphodiesterase 3b;
DE            EC=3.1.4.-;
DE   Flags: Precursor;
GN   Name=SMPDL3B; Synonyms=ASML3B;
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0006685; P:sphingomyelin catabolic process; IEA:InterPro.
//
ID   ASML_HUMAN              Reviewed;         621 AA.
AC   O95671; B4DX75; F5GXH4; J3JS33; Q5JQ53; Q8NBH5; Q96G02; Q9BUL6;
DE   RecName: Full=N-acetylserotonin O-methyltransferase-like protein;
DE            Short=ASMTL;
DE            EC=2.1.1.-;
GN   Name=ASMTL;
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
//
ID   ASMT_HUMAN              Reviewed;         345 AA.
AC   P46597; B2RC33; Q16598; Q5JQ72; Q5JQ73;
DE   RecName: Full=Acetylserotonin O-methyltransferase;
DE            EC=2.1.1.4;
DE   AltName: Full=Hydroxyindole O-methyltransferase;
DE            Short=HIOMT;
GN   Name=ASMT;
DR   GO; GO:0017096; F:acetylserotonin O-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008171; F:O-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0046219; P:indolalkylamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0030187; P:melatonin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2000019; P:negative regulation of male gonad development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   ASM_HUMAN               Reviewed;         629 AA.
AC   P17405; A8K8M3; E9PKS3; P17406; Q13811; Q16837; Q16841;
DE   RecName: Full=Sphingomyelin phosphodiesterase;
DE            EC=3.1.4.12;
DE   AltName: Full=Acid sphingomyelinase;
DE            Short=aSMase;
DE   Flags: Precursor;
GN   Name=SMPD1; Synonyms=ASM;
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006685; P:sphingomyelin catabolic process; IEA:InterPro.
DR   GO; GO:0006684; P:sphingomyelin metabolic process; TAS:ProtInc.
DR   GO; GO:0023021; P:termination of signal transduction; IMP:BHF-UCL.
//
ID   ASNA_HUMAN              Reviewed;         348 AA.
AC   O43681; A6NHP8; A8K740; Q53FC6; Q92849;
DE   RecName: Full=ATPase ASNA1;
DE            EC=3.6.-.-;
DE   AltName: Full=Arsenical pump-driving ATPase;
DE   AltName: Full=Arsenite-stimulated ATPase;
DE   AltName: Full=Transmembrane domain recognition complex 40 kDa ATPase subunit;
DE   AltName: Full=hARSA-I;
DE   AltName: Full=hASNA-I;
GN   Name=ASNA1; Synonyms=ARSA, TRC40;
DR   GO; GO:0015105; F:arsenite transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015698; P:inorganic anion transport; TAS:GOC.
DR   GO; GO:0045048; P:protein insertion into ER membrane; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ASND1_HUMAN             Reviewed;         643 AA.
AC   Q9NWL6; D3DPH6; Q3LIC3; Q4ZG45;
DE   RecName: Full=Asparagine synthetase domain-containing protein 1;
DE   AltName: Full=HCV NS3-transactivated protein 1;
GN   Name=ASNSD1; Synonyms=NS3TP1; ORFNames=Nbla00058;
DR   GO; GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0006529; P:asparagine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
//
ID   ASNS_HUMAN              Reviewed;         561 AA.
AC   P08243; A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; P08184;
AC   Q15666; Q549T9; Q96HD0;
DE   RecName: Full=Asparagine synthetase [glutamine-hydrolyzing];
DE            EC=6.3.5.4;
DE   AltName: Full=Cell cycle control protein TS11;
DE   AltName: Full=Glutamine-dependent asparagine synthetase;
GN   Name=ASNS; Synonyms=TS11;
DR   GO; GO:0004066; F:asparagine synthase (glutamine-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048037; F:cofactor binding; IEA:Ensembl.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006529; P:asparagine biosynthetic process; IC:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0070981; P:L-asparagine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0032354; P:response to follicle-stimulating hormone; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0031427; P:response to methotrexate; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ASPC1_HUMAN             Reviewed;         553 AA.
AC   Q9BZE9; A8K3K9; Q7Z6N7; Q8WV59; Q96LS5; Q96M40;
DE   RecName: Full=Tether containing UBX domain for GLUT4;
DE   AltName: Full=Alveolar soft part sarcoma chromosomal region candidate gene 1 protein;
DE   AltName: Full=Alveolar soft part sarcoma locus;
DE   AltName: Full=Renal papillary cell carcinoma protein 17;
DE   AltName: Full=UBX domain-containing protein 9;
GN   Name=ASPSCR1; Synonyms=ASPL, RCC17, TUG, UBXD9, UBXN9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0046324; P:regulation of glucose import; IEA:Ensembl.
//
ID   ASPD_HUMAN              Reviewed;         283 AA.
AC   A6ND91; Q6NZ37;
DE   RecName: Full=Putative L-aspartate dehydrogenase;
DE            EC=1.4.1.21;
DE   AltName: Full=Aspartate dehydrogenase domain-containing protein;
GN   Name=ASPDH;
DR   GO; GO:0033735; F:aspartate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006742; P:NADP catabolic process; IEA:InterPro.
//
ID   ASPG_HUMAN              Reviewed;         346 AA.
AC   P20933; B2R7H2; D3DP47; Q4W5Q2; Q6FHN6; Q9UCK6; Q9UCK7; Q9UCK8;
DE   RecName: Full=N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase;
DE            EC=3.5.1.26;
DE   AltName: Full=Aspartylglucosaminidase;
DE   AltName: Full=Glycosylasparaginase;
DE   AltName: Full=N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase;
DE   Contains:
DE     RecName: Full=Glycosylasparaginase alpha chain;
DE   Contains:
DE     RecName: Full=Glycosylasparaginase beta chain;
DE   Flags: Precursor;
GN   Name=AGA;
DR   GO; GO:0003948; F:N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006517; P:protein deglycosylation; IDA:UniProtKB.
//
ID   ASPH1_HUMAN             Reviewed;         390 AA.
AC   Q5U4P2; A0AVE3; B7ZLZ3; Q8IW63; Q8N316; Q96H00;
DE   RecName: Full=Aspartate beta-hydroxylase domain-containing protein 1;
DE            EC=1.14.11.-;
GN   Name=ASPHD1;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0018193; P:peptidyl-amino acid modification; IEA:InterPro.
//
ID   ASPH2_HUMAN             Reviewed;         369 AA.
AC   Q6ICH7; B2RCH3; Q7L0W3; Q9NSN3;
DE   RecName: Full=Aspartate beta-hydroxylase domain-containing protein 2;
DE            EC=1.14.11.-;
GN   Name=ASPHD2;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0018193; P:peptidyl-amino acid modification; IEA:InterPro.
//
ID   ASPH_HUMAN              Reviewed;         758 AA.
AC   Q12797; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667;
AC   Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0;
DE   RecName: Full=Aspartyl/asparaginyl beta-hydroxylase;
DE            EC=1.14.11.16;
DE   AltName: Full=Aspartate beta-hydroxylase;
DE            Short=ASP beta-hydroxylase;
DE   AltName: Full=Peptide-aspartate beta-dioxygenase;
GN   Name=ASPH;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; TAS:BHF-UCL.
DR   GO; GO:0004597; F:peptide-aspartate beta-dioxygenase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0032237; P:activation of store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0005513; P:detection of calcium ion; TAS:BHF-UCL.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0042264; P:peptidyl-aspartic acid hydroxylation; IEA:Ensembl.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:UniProtKB.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; ISS:BHF-UCL.
DR   GO; GO:0010649; P:regulation of cell communication by electrical coupling; TAS:BHF-UCL.
DR   GO; GO:0031585; P:regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IDA:UniProtKB.
DR   GO; GO:1901879; P:regulation of protein depolymerization; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; TAS:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
DR   GO; GO:0033198; P:response to ATP; IDA:UniProtKB.
//
ID   ASPM_HUMAN              Reviewed;        3477 AA.
AC   Q8IZT6; Q4G1H1; Q5VYL3; Q86UX4; Q8IUL2; Q8IZJ7; Q8IZJ8; Q8IZJ9;
AC   Q8N4D1; Q9NVS1; Q9NVT6;
DE   RecName: Full=Abnormal spindle-like microcephaly-associated protein;
DE   AltName: Full=Abnormal spindle protein homolog;
DE            Short=Asp homolog;
GN   Name=ASPM; Synonyms=MCPH5;
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0021873; P:forebrain neuroblast division; IEA:Ensembl.
DR   GO; GO:0051661; P:maintenance of centrosome location; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0045769; P:negative regulation of asymmetric cell division; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   ASPN_HUMAN              Reviewed;         380 AA.
AC   Q9BXN1; Q5TBF3; Q96K79; Q96LD0; Q9NXP3;
DE   RecName: Full=Asporin;
DE   AltName: Full=Periodontal ligament-associated protein 1;
DE            Short=PLAP-1;
DE   Flags: Precursor;
GN   Name=ASPN; Synonyms=PLAP1, SLRR1C; ORFNames=UNQ215/PRO241;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IDA:UniProtKB.
DR   GO; GO:0070171; P:negative regulation of tooth mineralization; ISS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
//
ID   ASPP1_HUMAN             Reviewed;        1090 AA.
AC   Q96KQ4; B2RMX5; O94870;
DE   RecName: Full=Apoptosis-stimulating of p53 protein 1;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 13B;
GN   Name=PPP1R13B; Synonyms=ASPP1, KIAA0771;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.
//
ID   ASPP2_HUMAN             Reviewed;        1128 AA.
AC   Q13625; B4DG66; Q12892; Q86X75; Q96KQ3;
DE   RecName: Full=Apoptosis-stimulating of p53 protein 2;
DE   AltName: Full=Bcl2-binding protein;
DE            Short=Bbp;
DE   AltName: Full=Renal carcinoma antigen NY-REN-51;
DE   AltName: Full=Tumor suppressor p53-binding protein 2;
DE            Short=53BP2;
DE            Short=p53-binding protein 2;
DE            Short=p53BP2;
GN   Name=TP53BP2; Synonyms=ASPP2, BBP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ASPX_HUMAN              Reviewed;         265 AA.
AC   P26436; Q53FF4;
DE   RecName: Full=Acrosomal protein SP-10;
DE   AltName: Full=Acrosomal vesicle protein 1;
DE   Flags: Precursor;
GN   Name=ACRV1;
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   ASSY_HUMAN              Reviewed;         412 AA.
AC   P00966; Q6LDL2; Q86UZ0; Q96GT4;
DE   RecName: Full=Argininosuccinate synthase;
DE            EC=6.3.4.5;
DE   AltName: Full=Citrulline--aspartate ligase;
GN   Name=ASS1; Synonyms=ASS;
DR   GO; GO:0004055; F:argininosuccinate synthase activity; EXP:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
//
ID   ASTE1_HUMAN             Reviewed;         679 AA.
AC   Q2TB18; Q3MIB6; Q8N6G4; Q96JY1; Q9UHX6;
DE   RecName: Full=Protein asteroid homolog 1;
GN   Name=ASTE1; ORFNames=HT001;
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
//
ID   ASTER_HUMAN             Reviewed;         106 AA.
AC   Q9Y284; B2R4T8; Q9BVI3;
DE   RecName: Full=Protein Asterix;
DE   AltName: Full=WD repeat domain 83 opposite strand;
DE   AltName: Full=WDR83 opposite strand;
GN   Name=WDR83OS; Synonyms=C19orf56; ORFNames=CGI-140, My006, PTD008;
//
ID   ASTL_HUMAN              Reviewed;         431 AA.
AC   Q6HA08; Q3KNT0;
DE   RecName: Full=Astacin-like metalloendopeptidase;
DE            EC=3.4.-.-;
DE   AltName: Full=Oocyte astacin;
DE   AltName: Full=Ovastacin;
DE   Flags: Precursor;
GN   Name=ASTL;
DR   GO; GO:0070001; F:aspartic-type peptidase activity; ISS:UniProtKB.
DR   GO; GO:0070002; F:glutamic-type peptidase activity; ISS:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; ISS:UniProtKB.
DR   GO; GO:2000360; P:negative regulation of binding of sperm to zona pellucida; ISS:UniProtKB.
DR   GO; GO:0010954; P:positive regulation of protein processing; ISS:UniProtKB.
DR   GO; GO:0060468; P:prevention of polyspermy; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:MGI.
//
ID   ASTN1_HUMAN             Reviewed;        1302 AA.
AC   O14525; A5PL12; B4DHI9; E9PFR8; O60799; Q5W0V7; Q5W0V8;
DE   RecName: Full=Astrotactin-1;
DE   Flags: Precursor;
GN   Name=ASTN1; Synonyms=ASTN, KIAA0289;
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
//
ID   ASTN2_HUMAN             Reviewed;        1339 AA.
AC   O75129; A2A2T7; A2A2T9; Q52LQ2; Q5JVX8; Q5JVX9; Q5JVY1; Q5VXG8;
AC   Q5VZX6; Q8N6P8; Q8WV47; Q96FL4; Q9UHW6;
DE   RecName: Full=Astrotactin-2;
DE   Flags: Precursor;
GN   Name=ASTN2; Synonyms=KIAA0634;
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IEA:Ensembl.
//
ID   ASUN_HUMAN              Reviewed;         706 AA.
AC   Q9NVM9; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5;
DE   RecName: Full=Protein asunder homolog;
DE   AltName: Full=Cell cycle regulator Mat89Bb homolog;
DE   AltName: Full=Germ cell tumor 1;
DE   AltName: Full=Sarcoma antigen NY-SAR-95;
GN   Name=ASUN; Synonyms=C12orf11, GCT1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0080154; P:regulation of fertilization; ISS:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; ISS:UniProtKB.
//
ID   ASXL1_HUMAN             Reviewed;        1541 AA.
AC   Q8IXJ9; B2RP59; Q5JWS9; Q8IYY7; Q9H466; Q9NQF8; Q9UFJ0; Q9UFP8;
AC   Q9Y2I4;
DE   RecName: Full=Putative Polycomb group protein ASXL1;
DE   AltName: Full=Additional sex combs-like protein 1;
GN   Name=ASXL1; Synonyms=KIAA0978;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042974; F:retinoic acid receptor binding; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0035522; P:monoubiquitinated histone H2A deubiquitination; IDA:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0035359; P:negative regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0048386; P:positive regulation of retinoic acid receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASXL2_HUMAN             Reviewed;        1435 AA.
AC   Q76L83; Q53TC9; Q5H9U4; Q76L81; Q86XM1; Q9C0H8; Q9NV67;
DE   RecName: Full=Putative Polycomb group protein ASXL2;
DE   AltName: Full=Additional sex combs-like protein 2;
GN   Name=ASXL2; Synonyms=ASXH2, KIAA1685;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042975; F:peroxisome proliferator activated receptor binding; IDA:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IDA:UniProtKB.
DR   GO; GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASXL3_HUMAN             Reviewed;        2248 AA.
AC   Q9C0F0; Q6ZMX6; Q96MU3; Q9UFC5;
DE   RecName: Full=Putative Polycomb group protein ASXL3;
DE   AltName: Full=Additional sex combs-like protein 3;
GN   Name=ASXL3; Synonyms=KIAA1713;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ASZ1_HUMAN              Reviewed;         475 AA.
AC   Q8WWH4; A0AV27; A4D0V0;
DE   RecName: Full=Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1;
DE   AltName: Full=Ankyrin-like protein 1;
DE   AltName: Full=Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein;
GN   Name=ASZ1; Synonyms=ALP1, ANKL1, C7orf7, GASZ;
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   AT10A_HUMAN             Reviewed;        1499 AA.
AC   O60312; Q969I4;
DE   RecName: Full=Probable phospholipid-transporting ATPase VA;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class V type 10A;
DE   AltName: Full=Aminophospholipid translocase VA;
GN   Name=ATP10A; Synonyms=ATP10C, ATPVA, ATPVC, KIAA0566;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT10B_HUMAN             Reviewed;        1461 AA.
AC   O94823; Q9H725;
DE   RecName: Full=Probable phospholipid-transporting ATPase VB;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class V type 10B;
GN   Name=ATP10B; Synonyms=ATPVB, KIAA0715;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
//
ID   AT10D_HUMAN             Reviewed;        1426 AA.
AC   Q9P241; A2RRC8; D6REN2; Q8NC70; Q96SR3;
DE   RecName: Full=Probable phospholipid-transporting ATPase VD;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class V type 10D;
GN   Name=ATP10D; Synonyms=ATPVD, KIAA1487;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; NAS:UniProtKB.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006812; P:cation transport; NAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT11A_HUMAN             Reviewed;        1134 AA.
AC   P98196; Q5VXT2;
DE   RecName: Full=Probable phospholipid-transporting ATPase IH;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase IS;
DE   AltName: Full=ATPase class VI type 11A;
GN   Name=ATP11A; Synonyms=ATPIH, ATPIS, KIAA1021;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
//
ID   AT11B_HUMAN             Reviewed;        1177 AA.
AC   Q9Y2G3; Q96FN1; Q9UKK7;
DE   RecName: Full=Probable phospholipid-transporting ATPase IF;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase IR;
DE   AltName: Full=ATPase class VI type 11B;
GN   Name=ATP11B; Synonyms=ATPIF, ATPIR, KIAA0956;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0015075; F:ion transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015917; P:aminophospholipid transport; TAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT11C_HUMAN             Reviewed;        1132 AA.
AC   Q8NB49; Q5JT69; Q5JT70; Q5JT71; Q5JT72; Q5JT73; Q6ZND5; Q6ZU50;
AC   Q6ZUP7; Q70IJ9; Q70IK0; Q8WX24;
DE   RecName: Full=Probable phospholipid-transporting ATPase IG;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase IQ;
DE   AltName: Full=ATPase class VI type 11C;
GN   Name=ATP11C; Synonyms=ATPIG, ATPIQ;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT12A_HUMAN             Reviewed;        1039 AA.
AC   P54707; Q13816; Q13817; Q16734; Q5W035; Q8N5U2;
DE   RecName: Full=Potassium-transporting ATPase alpha chain 2;
DE            EC=3.6.3.10;
DE   AltName: Full=Non-gastric H(+)/K(+) ATPase subunit alpha;
DE   AltName: Full=Proton pump;
GN   Name=ATP12A; Synonyms=ATP1AL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055075; P:potassium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT131_HUMAN             Reviewed;        1204 AA.
AC   Q9HD20; B3KPJ2; B3KTA7; Q9H6C6;
DE   RecName: Full=Probable cation-transporting ATPase 13A1;
DE            EC=3.6.3.-;
GN   Name=ATP13A1; Synonyms=ATP13A, KIAA1825; ORFNames=CGI-152;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   AT132_HUMAN             Reviewed;        1180 AA.
AC   Q9NQ11; O75700; Q5JXY1; Q5JXY2; Q6S9Z9;
DE   RecName: Full=Probable cation-transporting ATPase 13A2;
DE            EC=3.6.3.-;
GN   Name=ATP13A2; Synonyms=PARK9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   AT133_HUMAN             Reviewed;        1226 AA.
AC   Q9H7F0; Q8NC11; Q96KS1;
DE   RecName: Full=Probable cation-transporting ATPase 13A3;
DE            EC=3.6.3.-;
DE   AltName: Full=ATPase family homolog up-regulated in senescence cells 1;
GN   Name=ATP13A3; Synonyms=AFURS1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   AT134_HUMAN             Reviewed;        1196 AA.
AC   Q4VNC1; B7WPC7; Q6UY23; Q8N1Q9; Q9H043;
DE   RecName: Full=Probable cation-transporting ATPase 13A4;
DE            EC=3.6.3.-;
DE   AltName: Full=P5-ATPase isoform 4;
GN   Name=ATP13A4; ORFNames=UNQ3052/PRO9871;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   AT135_HUMAN             Reviewed;        1218 AA.
AC   Q4VNC0; Q6UWS4; Q6ZWL0;
DE   RecName: Full=Probable cation-transporting ATPase 13A5;
DE            EC=3.6.3.-;
DE   AltName: Full=P5-ATPase isoform 5;
GN   Name=ATP13A5; ORFNames=UNQ488/PRO1004;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   AT1A1_HUMAN             Reviewed;        1023 AA.
AC   P05023; B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; Q16689; Q6LDM4; Q9UCN1;
AC   Q9UJ20; Q9UJ21;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit alpha-1;
DE            Short=Na(+)/K(+) ATPase alpha-1 subunit;
DE            EC=3.6.3.9;
DE   AltName: Full=Sodium pump subunit alpha-1;
DE   Flags: Precursor;
GN   Name=ATP1A1;
DR   GuidetoPHARMACOLOGY; 833; -.
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051087; F:chaperone binding; ISS:BHF-UCL.
DR   GO; GO:0030955; F:potassium ion binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031402; F:sodium ion binding; IEA:Ensembl.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0031947; P:negative regulation of glucocorticoid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045822; P:negative regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0045823; P:positive regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0045989; P:positive regulation of striated muscle contraction; IEA:Ensembl.
DR   GO; GO:0010107; P:potassium ion import; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IEA:Ensembl.
DR   GO; GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; ISS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT1A2_HUMAN             Reviewed;        1020 AA.
AC   P50993; D3DVE4; Q07059; Q5JW74; Q86UZ5; Q9UQ25;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit alpha-2;
DE            Short=Na(+)/K(+) ATPase alpha-2 subunit;
DE            EC=3.6.3.9;
DE   AltName: Full=Sodium pump subunit alpha-2;
DE   Flags: Precursor;
GN   Name=ATP1A2; Synonyms=KIAA0778;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; IMP:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0040011; P:locomotion; IEA:Ensembl.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0045822; P:negative regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0045988; P:negative regulation of striated muscle contraction; IEA:Ensembl.
DR   GO; GO:0001504; P:neurotransmitter uptake; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; NAS:UniProtKB.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   AT1A3_HUMAN             Reviewed;        1013 AA.
AC   P13637; B7Z2T0; B7Z401; F5H6J6; Q16732; Q16735; Q969K5;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit alpha-3;
DE            Short=Na(+)/K(+) ATPase alpha-3 subunit;
DE            EC=3.6.3.9;
DE   AltName: Full=Na(+)/K(+) ATPase alpha(III) subunit;
DE   AltName: Full=Sodium pump subunit alpha-3;
GN   Name=ATP1A3;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; IMP:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IMP:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   AT1A4_HUMAN             Reviewed;        1029 AA.
AC   Q13733; Q504T2; Q7Z4I9; Q8TBN8; Q8WXA7; Q8WXH7; Q8WY13;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit alpha-4;
DE            Short=Na(+)/K(+) ATPase alpha-4 subunit;
DE            EC=3.6.3.9;
DE   AltName: Full=Sodium pump subunit alpha-4;
GN   Name=ATP1A4; Synonyms=ATP1AL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; TAS:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; TAS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:UniProtKB.
DR   GO; GO:0030641; P:regulation of cellular pH; IDA:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; TAS:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT1B2_HUMAN             Reviewed;         290 AA.
AC   P14415; A0AV17; A8K278; D3DTQ2; O60444;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-2;
DE   AltName: Full=Adhesion molecule in glia;
DE            Short=AMOG;
DE   AltName: Full=Sodium/potassium-dependent ATPase subunit beta-2;
GN   Name=ATP1B2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT1B1_HUMAN             Reviewed;         303 AA.
AC   P05026; Q5TGZ3;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1;
DE   AltName: Full=Sodium/potassium-dependent ATPase subunit beta-1;
GN   Name=ATP1B1; Synonyms=ATP1B;
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT1B4_HUMAN             Reviewed;         357 AA.
AC   Q9UN42; Q17RR0; Q9UN41;
DE   RecName: Full=Protein ATP1B4;
DE   AltName: Full=X,K-ATPase subunit beta-m;
DE   AltName: Full=X/potassium-transporting ATPase subunit beta-m;
GN   Name=ATP1B4;
DR   GO; GO:0015077; F:monovalent inorganic cation transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015672; P:monovalent inorganic cation transport; TAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT1B3_HUMAN             Reviewed;         279 AA.
AC   P54709;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-3;
DE   AltName: Full=Sodium/potassium-dependent ATPase subunit beta-3;
DE            Short=ATPB-3;
DE   AltName: CD_antigen=CD298;
GN   Name=ATP1B3;
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT2A1_HUMAN             Reviewed;        1001 AA.
AC   O14983; A8K5J9; B3KY17; O14984;
DE   RecName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 1;
DE            Short=SERCA1;
DE            Short=SR Ca(2+)-ATPase 1;
DE            EC=3.6.3.8;
DE   AltName: Full=Calcium pump 1;
DE   AltName: Full=Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform;
DE   AltName: Full=Endoplasmic reticulum class 1/2 Ca(2+) ATPase;
GN   Name=ATP2A1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IMP:UniProtKB.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IMP:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IMP:BHF-UCL.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051659; P:maintenance of mitochondrion location; IMP:BHF-UCL.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IMP:BHF-UCL.
DR   GO; GO:0045988; P:negative regulation of striated muscle contraction; IMP:UniProtKB.
DR   GO; GO:0032470; P:positive regulation of endoplasmic reticulum calcium ion concentration; IMP:BHF-UCL.
DR   GO; GO:0031448; P:positive regulation of fast-twitch skeletal muscle fiber contraction; IDA:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IMP:BHF-UCL.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; IMP:UniProtKB.
DR   GO; GO:0090076; P:relaxation of skeletal muscle; IDA:BHF-UCL.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT2A2_HUMAN             Reviewed;        1042 AA.
AC   P16615; A6NDN7; B4DF05; P16614; Q86VJ2;
DE   RecName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 2;
DE            Short=SERCA2;
DE            Short=SR Ca(2+)-ATPase 2;
DE            EC=3.6.3.8;
DE   AltName: Full=Calcium pump 2;
DE   AltName: Full=Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform;
DE   AltName: Full=Endoplasmic reticulum class 1/2 Ca(2+) ATPase;
GN   Name=ATP2A2; Synonyms=ATP2B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0086039; F:calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential; TAS:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:BHF-UCL.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0006984; P:ER-nucleus signaling pathway; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045822; P:negative regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; TAS:BHF-UCL.
DR   GO; GO:0086036; P:regulation of cardiac muscle cell membrane potential; TAS:BHF-UCL.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; TAS:BHF-UCL.
DR   GO; GO:0070296; P:sarcoplasmic reticulum calcium ion transport; TAS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT2A3_HUMAN             Reviewed;        1043 AA.
AC   Q93084; A8MZG0; D3DTJ8; O60900; O60901; O75501; O75502; Q16115;
AC   Q6JHX1; Q8TEX5; Q8TEX6;
DE   RecName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 3;
DE            Short=SERCA3;
DE            Short=SR Ca(2+)-ATPase 3;
DE            EC=3.6.3.8;
DE   AltName: Full=Calcium pump 3;
GN   Name=ATP2A3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006816; P:calcium ion transport; TAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT2B1_HUMAN             Reviewed;        1258 AA.
AC   P20020; Q12992; Q12993; Q13819; Q13820; Q13821; Q16504; Q93082;
DE   RecName: Full=Plasma membrane calcium-transporting ATPase 1;
DE            Short=PMCA1;
DE            EC=3.6.3.8;
DE   AltName: Full=Plasma membrane calcium ATPase isoform 1;
DE   AltName: Full=Plasma membrane calcium pump isoform 1;
GN   Name=ATP2B1; Synonyms=PMCA1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT2B2_HUMAN             Reviewed;        1243 AA.
AC   Q01814; O00766; Q12994; Q16818;
DE   RecName: Full=Plasma membrane calcium-transporting ATPase 2;
DE            Short=PMCA2;
DE            EC=3.6.3.8;
DE   AltName: Full=Plasma membrane calcium ATPase isoform 2;
DE   AltName: Full=Plasma membrane calcium pump isoform 2;
GN   Name=ATP2B2; Synonyms=PMCA2;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0030899; F:calcium-dependent ATPase activity; IEA:Ensembl.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006816; P:calcium ion transport; IMP:DFLAT.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; IEA:Ensembl.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0046068; P:cGMP metabolic process; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IMP:DFLAT.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0040011; P:locomotion; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IDA:UniProtKB.
DR   GO; GO:0006996; P:organelle organization; IEA:Ensembl.
DR   GO; GO:0045299; P:otolith mineralization; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0042428; P:serotonin metabolic process; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   AT2B3_HUMAN             Reviewed;        1220 AA.
AC   Q16720; B7WNR8; B7WNY5; Q12995; Q16858;
DE   RecName: Full=Plasma membrane calcium-transporting ATPase 3;
DE            Short=PMCA3;
DE            EC=3.6.3.8;
DE   AltName: Full=Plasma membrane calcium ATPase isoform 3;
DE   AltName: Full=Plasma membrane calcium pump isoform 3;
GN   Name=ATP2B3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT2B4_HUMAN             Reviewed;        1241 AA.
AC   P23634; B1APW5; B1APW6; Q13450; Q13452; Q13455; Q16817; Q7Z3S1;
DE   RecName: Full=Plasma membrane calcium-transporting ATPase 4;
DE            Short=PMCA4;
DE            EC=3.6.3.8;
DE   AltName: Full=Matrix-remodeling-associated protein 1;
DE   AltName: Full=Plasma membrane calcium ATPase isoform 4;
DE   AltName: Full=Plasma membrane calcium pump isoform 4;
GN   Name=ATP2B4; Synonyms=ATP2B2, MXRA1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:1902083; P:negative regulation of peptidyl-cysteine S-nitrosylation; NAS:BHF-UCL.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; IC:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   AT2C1_HUMAN             Reviewed;         919 AA.
AC   P98194; B2RAT7; B4DSW3; B7Z3X9; G3XAH8; G8JLN9; O76005; Q86V72;
AC   Q86V73; Q8N6V1; Q8NCJ7;
DE   RecName: Full=Calcium-transporting ATPase type 2C member 1;
DE            Short=ATPase 2C1;
DE            EC=3.6.3.8;
DE   AltName: Full=ATP-dependent Ca(2+) pump PMR1;
GN   Name=ATP2C1; Synonyms=KIAA1347, PMR1L; ORFNames=HUSSY-28;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0015410; F:manganese-transporting ATPase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0030026; P:cellular manganese ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; IMP:UniProtKB.
DR   GO; GO:0032468; P:Golgi calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0032472; P:Golgi calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0071421; P:manganese ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006828; P:manganese ion transport; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT2C2_HUMAN             Reviewed;         946 AA.
AC   O75185; B4DU76; E7ES94; Q5HYC3; Q5S053; Q68CQ2;
DE   RecName: Full=Calcium-transporting ATPase type 2C member 2;
DE            Short=ATPase 2C2;
DE            EC=3.6.3.8;
DE   AltName: Full=Secretory pathway Ca(2+)-ATPase 2;
GN   Name=ATP2C2; Synonyms=KIAA0703, SPCA2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005388; F:calcium-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT2L1_HUMAN             Reviewed;         499 AA.
AC   Q8TBG4; B7Z1Y0; E9PBY0; Q9H174;
DE   RecName: Full=Ethanolamine-phosphate phospho-lyase;
DE            EC=4.2.3.2;
DE   AltName: Full=Alanine--glyoxylate aminotransferase 2-like 1;
GN   Name=ETNPPL; Synonyms=AGXT2L1;
DR   GO; GO:0050459; F:ethanolamine-phosphate phospho-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
//
ID   AT2L2_HUMAN             Reviewed;         450 AA.
AC   Q8IUZ5; A8K7P6; B3KN36; D3DWP9; Q8WYS6; Q96HW8;
DE   RecName: Full=5-phosphohydroxy-L-lysine phospho-lyase;
DE            EC=4.2.3.134;
DE   AltName: Full=Alanine--glyoxylate aminotransferase 2-like 2;
GN   Name=PHYKPL; Synonyms=AGXT2L2; ORFNames=PP9286;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
//
ID   AT5G2_HUMAN             Reviewed;         141 AA.
AC   Q06055; B3KQQ6;
DE   RecName: Full=ATP synthase F(0) complex subunit C2, mitochondrial;
DE   AltName: Full=ATP synthase lipid-binding protein;
DE   AltName: Full=ATP synthase proteolipid P2;
DE   AltName: Full=ATP synthase proton-transporting mitochondrial F(0) complex subunit C2;
DE   AltName: Full=ATPase protein 9;
DE   AltName: Full=ATPase subunit c;
DE   Flags: Precursor;
GN   Name=ATP5G2; ORFNames=PSEC0033;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
//
ID   AT5G1_HUMAN             Reviewed;         136 AA.
AC   P05496;
DE   RecName: Full=ATP synthase F(0) complex subunit C1, mitochondrial;
DE   AltName: Full=ATP synthase lipid-binding protein;
DE   AltName: Full=ATP synthase proteolipid P1;
DE   AltName: Full=ATP synthase proton-transporting mitochondrial F(0) complex subunit C1;
DE   AltName: Full=ATPase protein 9;
DE   AltName: Full=ATPase subunit c;
DE   Flags: Precursor;
GN   Name=ATP5G1;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AT5EL_HUMAN             Reviewed;          51 AA.
AC   Q5VTU8;
DE   RecName: Full=ATP synthase subunit epsilon-like protein, mitochondrial;
GN   Name=ATP5EP2;
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
//
ID   AT5G3_HUMAN             Reviewed;         142 AA.
AC   P48201; B2R4Z0; D3DPF0; Q4ZFX7;
DE   RecName: Full=ATP synthase F(0) complex subunit C3, mitochondrial;
DE   AltName: Full=ATP synthase lipid-binding protein;
DE   AltName: Full=ATP synthase proteolipid P3;
DE   AltName: Full=ATP synthase proton-transporting mitochondrial F(0) complex subunit C3;
DE   AltName: Full=ATPase protein 9;
DE   AltName: Full=ATPase subunit c;
DE   Flags: Precursor;
GN   Name=ATP5G3;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
//
ID   AT5SL_HUMAN             Reviewed;         257 AA.
AC   Q9NW81; B4DDC0; B4DMZ4; B4DP55; B4DXE8; F5H4W7; K7EMF6; Q96D43;
DE   RecName: Full=ATP synthase subunit s-like protein;
GN   Name=ATP5SL;
//
ID   AT5L2_HUMAN             Reviewed;         100 AA.
AC   Q7Z4Y8;
DE   RecName: Full=ATP synthase subunit g 2, mitochondrial;
DE            Short=ATPase subunit g 2;
GN   Name=ATP5L2; Synonyms=ATP5K2;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
//
ID   AT5F1_HUMAN             Reviewed;         256 AA.
AC   P24539; Q9BQ68; Q9BRU8;
DE   RecName: Full=ATP synthase F(0) complex subunit B1, mitochondrial;
DE   AltName: Full=ATP synthase proton-transporting mitochondrial F(0) complex subunit B1;
DE   AltName: Full=ATP synthase subunit b;
DE            Short=ATPase subunit b;
DE   Flags: Precursor;
GN   Name=ATP5F1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IBA:RefGenome.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; IBA:RefGenome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   AT7L1_HUMAN             Reviewed;         861 AA.
AC   Q9ULK2; A4D0Q2; B4DTS1; Q8N2T0;
DE   RecName: Full=Ataxin-7-like protein 1;
DE   AltName: Full=Ataxin-7-like protein 4;
GN   Name=ATXN7L1; Synonyms=ATXN7L4, KIAA1218;
//
ID   AT7L3_HUMAN             Reviewed;         347 AA.
AC   Q14CW9; Q8IY68; Q96N40; Q9NPU5;
DE   RecName: Full=Ataxin-7-like protein 3;
DE   AltName: Full=SAGA-associated factor 11 homolog;
GN   Name=ATXN7L3;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   AT7L2_HUMAN             Reviewed;         722 AA.
AC   Q5T6C5;
DE   RecName: Full=Ataxin-7-like protein 2;
GN   Name=ATXN7L2;
//
ID   AT8A1_HUMAN             Reviewed;        1164 AA.
AC   Q9Y2Q0; Q32M35; Q32M36; Q4W5J7; Q4W5P2;
DE   RecName: Full=Probable phospholipid-transporting ATPase IA;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class I type 8A member 1;
DE   AltName: Full=Chromaffin granule ATPase II;
GN   Name=ATP8A1; Synonyms=ATPIA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; NAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT8A2_HUMAN             Reviewed;        1148 AA.
AC   Q9NTI2; Q9H527; Q9NPU6; Q9NTL2; Q9NYM3;
DE   RecName: Full=Probable phospholipid-transporting ATPase IB;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class I type 8A member 2;
DE   AltName: Full=ML-1;
GN   Name=ATP8A2; Synonyms=ATPIB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0003011; P:involuntary skeletal muscle contraction; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
//
ID   AT8B1_HUMAN             Reviewed;        1251 AA.
AC   O43520; Q9BTP8;
DE   RecName: Full=Probable phospholipid-transporting ATPase IC;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class I type 8B member 1;
DE   AltName: Full=Familial intrahepatic cholestasis type 1;
GN   Name=ATP8B1; Synonyms=ATPIC, FIC1, PFIC;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015721; P:bile acid and bile salt transport; NAS:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT8B3_HUMAN             Reviewed;        1300 AA.
AC   O60423; Q7Z485; Q8IVB8; Q8N4Y8; Q96M22;
DE   RecName: Full=Probable phospholipid-transporting ATPase IK;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class I type 8B member 3;
GN   Name=ATP8B3; Synonyms=ATP1K, FOS37502_2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
//
ID   AT8B2_HUMAN             Reviewed;        1209 AA.
AC   P98198; B4E3P4; Q6NT69; Q7Z486; Q96I43; Q96NQ7;
DE   RecName: Full=Probable phospholipid-transporting ATPase ID;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class I type 8B member 2;
GN   Name=ATP8B2; Synonyms=ATPID, KIAA1137;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   AT8B4_HUMAN             Reviewed;        1192 AA.
AC   Q8TF62; Q9H727;
DE   RecName: Full=Probable phospholipid-transporting ATPase IM;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class I type 8B member 4;
GN   Name=ATP8B4; Synonyms=KIAA1939;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
//
ID   ATAD1_HUMAN             Reviewed;         361 AA.
AC   Q8NBU5; D3DR26; Q6DKG1; Q6P4B9; Q8N3G1; Q8WYR9; Q969Y3;
DE   RecName: Full=ATPase family AAA domain-containing protein 1;
DE            EC=3.6.1.3;
DE   AltName: Full=Thorase;
GN   Name=ATAD1; ORFNames=FNP001;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0007612; P:learning; ISS:UniProtKB.
DR   GO; GO:0007613; P:memory; ISS:UniProtKB.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; ISS:UniProtKB.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.
//
ID   ATAD2_HUMAN             Reviewed;        1390 AA.
AC   Q6PL18; Q14CR1; Q658P2; Q68CQ0; Q6PJV6; Q8N890; Q9UHS5;
DE   RecName: Full=ATPase family AAA domain-containing protein 2;
DE            EC=3.6.1.3;
DE   AltName: Full=AAA nuclear coregulator cancer-associated protein;
DE            Short=ANCCA;
GN   Name=ATAD2; ORFNames=L16, PRO2000;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProt.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProt.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATAD5_HUMAN             Reviewed;        1844 AA.
AC   Q96QE3; Q05DH0; Q69YR6; Q9H9I1;
DE   RecName: Full=ATPase family AAA domain-containing protein 5;
DE   AltName: Full=Chromosome fragility-associated gene 1 protein;
GN   Name=ATAD5; Synonyms=C17orf41, FRAG1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
//
ID   ATAT_HUMAN              Reviewed;         421 AA.
AC   Q5SQI0; A2AB28; Q3LIB0; Q5JP39; Q5JP40; Q5JP42; Q5SQI1; Q5SU03;
AC   Q86X42; Q8NDK9; Q9BRS1; Q9H8X5;
DE   RecName: Full=Alpha-tubulin N-acetyltransferase 1;
DE            Short=Alpha-TAT;
DE            Short=Alpha-TAT1;
DE            Short=TAT;
DE            EC=2.3.1.108;
DE   AltName: Full=Acetyltransferase mec-17 homolog;
GN   Name=ATAT1; Synonyms=C6orf134, MEC17; ORFNames=Nbla00487;
DR   GO; GO:0019799; F:tubulin N-acetyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0071929; P:alpha-tubulin acetylation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0048666; P:neuron development; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IEA:UniProtKB-HAMAP.
//
ID   ATCAY_HUMAN             Reviewed;         371 AA.
AC   Q86WG3; Q8NAQ2; Q8TAQ3; Q96HC6; Q96JF5;
DE   RecName: Full=Caytaxin;
DE   AltName: Full=Ataxia cayman type protein;
DE   AltName: Full=BNIP-2-homology;
DE            Short=BNIP-H;
GN   Name=ATCAY; Synonyms=KIAA1872;
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0048311; P:mitochondrion distribution; ISS:UniProtKB.
DR   GO; GO:2000212; P:negative regulation of glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   ATD2B_HUMAN             Reviewed;        1458 AA.
AC   Q9ULI0; B9ZVQ5; Q6ZNA6; Q8N9E7;
DE   RecName: Full=ATPase family AAA domain-containing protein 2B;
GN   Name=ATAD2B; Synonyms=KIAA1240;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
//
ID   ATD3A_HUMAN             Reviewed;         634 AA.
AC   Q9NVI7; B3KPB3; D2K8Q1; G3V1I6; Q5SV23; Q8N275; Q96A50;
DE   RecName: Full=ATPase family AAA domain-containing protein 3A;
GN   Name=ATAD3A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0016049; P:cell growth; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
//
ID   ATD3B_HUMAN             Reviewed;         648 AA.
AC   Q5T9A4; A8K3H1; Q6ZRB5; Q9BUK4; Q9ULE7;
DE   RecName: Full=ATPase family AAA domain-containing protein 3B;
DE   AltName: Full=AAA-TOB3;
GN   Name=ATAD3B; Synonyms=KIAA1273, TOB3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
//
ID   ATD3C_HUMAN             Reviewed;         411 AA.
AC   Q5T2N8; Q8N1Z5;
DE   RecName: Full=ATPase family AAA domain-containing protein 3C;
GN   Name=ATAD3C;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
//
ID   ATE1_HUMAN              Reviewed;         518 AA.
AC   O95260; O95261; Q5SQQ3; Q8WW04;
DE   RecName: Full=Arginyl-tRNA--protein transferase 1;
DE            Short=Arginyltransferase 1;
DE            Short=R-transferase 1;
DE            EC=2.3.2.8;
DE   AltName: Full=Arginine-tRNA--protein transferase 1;
GN   Name=ATE1;
DR   GO; GO:0004057; F:arginyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016598; P:protein arginylation; NAS:UniProtKB.
//
ID   ATF1_HUMAN              Reviewed;         271 AA.
AC   P18846; P25168; Q9H4A8;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-1;
DE            Short=cAMP-dependent transcription factor ATF-1;
DE   AltName: Full=Activating transcription factor 1;
DE   AltName: Full=Protein TREB36;
GN   Name=ATF1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032025; P:response to cobalt ion; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   ATF2_HUMAN              Reviewed;         505 AA.
AC   P15336; A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5; Q13000;
AC   Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; Q96JT8;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-2;
DE            Short=cAMP-dependent transcription factor ATF-2;
DE            EC=2.3.1.48;
DE   AltName: Full=Activating transcription factor 2;
DE   AltName: Full=Cyclic AMP-responsive element-binding protein 2;
DE            Short=CREB-2;
DE            Short=cAMP-responsive element-binding protein 2;
DE   AltName: Full=HB16;
DE   AltName: Full=Histone acetyltransferase ATF2;
DE   AltName: Full=cAMP response element-binding protein CRE-BP1;
GN   Name=ATF2; Synonyms=CREB2, CREBP1;
DR   GO; GO:0035497; F:cAMP response element binding; IDA:BHF-UCL.
DR   GO; GO:0008140; F:cAMP response element binding protein binding; IDA:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IC:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0016573; P:histone acetylation; IDA:GOC.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:1902110; P:positive regulation of mitochondrial membrane permeability involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0032915; P:positive regulation of transforming growth factor beta2 production; IEA:Ensembl.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006970; P:response to osmotic stress; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IC:GOC.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   ATF4_HUMAN              Reviewed;         351 AA.
AC   P18848; Q9UH31;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-4;
DE            Short=cAMP-dependent transcription factor ATF-4;
DE   AltName: Full=Activating transcription factor 4;
DE   AltName: Full=Cyclic AMP-responsive element-binding protein 2;
DE            Short=CREB-2;
DE            Short=cAMP-responsive element-binding protein 2;
DE   AltName: Full=DNA-binding protein TAXREB67;
DE   AltName: Full=Tax-responsive enhancer element-binding protein 67;
DE            Short=TaxREB67;
GN   Name=ATF4; Synonyms=CREB2, TXREB;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR   GO; GO:0006094; P:gluconeogenesis; ISS:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   ATF3_HUMAN              Reviewed;         181 AA.
AC   P18847; Q5VTZ2; Q6ICQ9; Q7Z566; Q8WYM6;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-3;
DE            Short=cAMP-dependent transcription factor ATF-3;
DE   AltName: Full=Activating transcription factor 3;
GN   Name=ATF3;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATF5_HUMAN              Reviewed;         282 AA.
AC   Q9Y2D1; B3KND3; Q9BSA1; Q9UNQ3;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-5;
DE            Short=cAMP-dependent transcription factor ATF-5;
DE   AltName: Full=Activating transcription factor 5;
DE   AltName: Full=Transcription factor ATFx;
GN   Name=ATF5; Synonyms=ATFX;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0021891; P:olfactory bulb interneuron development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATF6A_HUMAN             Reviewed;         670 AA.
AC   P18850; O15139; Q5VW62; Q6IPB5; Q9UEC9;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-6 alpha;
DE            Short=cAMP-dependent transcription factor ATF-6 alpha;
DE   AltName: Full=Activating transcription factor 6 alpha;
DE            Short=ATF6-alpha;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-dependent transcription factor ATF-6 alpha;
GN   Name=ATF6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:BHF-UCL.
DR   GO; GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATF6B_HUMAN             Reviewed;         703 AA.
AC   Q99941; B0UYX6; Q13269; Q14343; Q14345; Q5SSW7; Q99635; Q99637;
AC   Q9H3V9; Q9H3W1; Q9NPL0;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-6 beta;
DE            Short=cAMP-dependent transcription factor ATF-6 beta;
DE   AltName: Full=Activating transcription factor 6 beta;
DE            Short=ATF6-beta;
DE   AltName: Full=Protein G13;
DE   AltName: Full=cAMP response element-binding protein-related protein;
DE            Short=Creb-rp;
DE   AltName: Full=cAMP-responsive element-binding protein-like 1;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-dependent transcription factor ATF-6 beta;
GN   Name=ATF6B; Synonyms=CREBL1, G13;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   ATF7_HUMAN              Reviewed;         494 AA.
AC   P17544; A5D6Y4; B2RMP1; B4DQL4; Q13814; Q8IVR8; Q9UD83;
DE   RecName: Full=Cyclic AMP-dependent transcription factor ATF-7;
DE            Short=cAMP-dependent transcription factor ATF-7;
DE   AltName: Full=Activating transcription factor 7;
DE   AltName: Full=Transcription factor ATF-A;
GN   Name=ATF7; Synonyms=ATFA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ATG10_HUMAN             Reviewed;         220 AA.
AC   Q9H0Y0; B2RE09; Q6PIX1; Q9H842;
DE   RecName: Full=Ubiquitin-like-conjugating enzyme ATG10;
DE            EC=6.3.2.-;
DE   AltName: Full=Autophagy-related protein 10;
DE            Short=APG10-like;
GN   Name=ATG10; Synonyms=APG10L; ORFNames=PP12616;
DR   GO; GO:0019777; F:Atg12 ligase activity; ISS:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0034263; P:autophagy in response to ER overload; IMP:UniProtKB.
DR   GO; GO:0031401; P:positive regulation of protein modification process; ISS:UniProtKB.
DR   GO; GO:0006497; P:protein lipidation; ISS:UniProtKB.
DR   GO; GO:0032446; P:protein modification by small protein conjugation; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   ATG12_HUMAN             Reviewed;         140 AA.
AC   O94817; Q6PJV2;
DE   RecName: Full=Ubiquitin-like protein ATG12;
DE   AltName: Full=Autophagy-related protein 12;
DE            Short=APG12-like;
GN   Name=ATG12; Synonyms=APG12, APG12L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
//
ID   ATG13_HUMAN             Reviewed;         517 AA.
AC   O75143; B4DFI4; D3DQQ1; D3DQQ2; E9PQZ8; Q53EN6; Q9BRL3; Q9H8B0;
DE   RecName: Full=Autophagy-related protein 13;
GN   Name=ATG13; Synonyms=KIAA0652;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.
//
ID   ATG2A_HUMAN             Reviewed;        1938 AA.
AC   Q2TAZ0; O43154; Q14DM2; Q6ZTV2; Q7Z6K8; Q8IVY5; Q8TAI8; Q96HH7;
DE   RecName: Full=Autophagy-related protein 2 homolog A;
GN   Name=ATG2A; Synonyms=KIAA0404;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   ATG2B_HUMAN             Reviewed;        2078 AA.
AC   Q96BY7; Q6ZRE7; Q96DQ3; Q9NW80;
DE   RecName: Full=Autophagy-related protein 2 homolog B;
GN   Name=ATG2B; Synonyms=C14orf103;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   ATG3_HUMAN              Reviewed;         314 AA.
AC   Q9NT62; Q6PKC5; Q9H6L9;
DE   RecName: Full=Ubiquitin-like-conjugating enzyme ATG3;
DE            EC=6.3.2.-;
DE   AltName: Full=Autophagy-related protein 3;
DE            Short=APG3-like;
DE            Short=hApg3;
DE   AltName: Full=Protein PC3-96;
GN   Name=ATG3; Synonyms=APG3, APG3L;
DR   GO; GO:0019777; F:Atg12 ligase activity; ISS:UniProtKB.
DR   GO; GO:0019776; F:Atg8 ligase activity; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019787; F:small conjugating protein ligase activity; IDA:MGI.
DR   GO; GO:0000045; P:autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:MGI.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:1902017; P:regulation of cilium assembly; ISS:UniProtKB.
//
ID   ATG4A_HUMAN             Reviewed;         398 AA.
AC   Q8WYN0; A6NCH2; B2RAZ7; D3DUY0; O95534; Q5JYY9; Q5JYZ0; Q86VE5;
AC   Q96KQ0; Q96KQ1;
DE   RecName: Full=Cysteine protease ATG4A;
DE            EC=3.4.22.-;
DE   AltName: Full=AUT-like 2 cysteine endopeptidase;
DE   AltName: Full=Autophagin-2;
DE   AltName: Full=Autophagy-related cysteine endopeptidase 2;
DE   AltName: Full=Autophagy-related protein 4 homolog A;
DE            Short=hAPG4A;
GN   Name=ATG4A; Synonyms=APG4A, AUTL2;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   ATG4B_HUMAN             Reviewed;         393 AA.
AC   Q9Y4P1; B7WNK2; Q53NU4; Q6ZUV8; Q8WYM9; Q96K07; Q96K96; Q96SZ1;
AC   Q9Y2F2;
DE   RecName: Full=Cysteine protease ATG4B;
DE            EC=3.4.22.-;
DE   AltName: Full=AUT-like 1 cysteine endopeptidase;
DE   AltName: Full=Autophagin-1;
DE   AltName: Full=Autophagy-related cysteine endopeptidase 1;
DE   AltName: Full=Autophagy-related protein 4 homolog B;
DE            Short=hAPG4B;
GN   Name=ATG4B; Synonyms=APG4B, AUTL1, KIAA0943;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IGI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IGI:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; IDA:BHF-UCL.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   ATG4C_HUMAN             Reviewed;         458 AA.
AC   Q96DT6; A6NLR8; D3DQ58; Q96K04;
DE   RecName: Full=Cysteine protease ATG4C;
DE            EC=3.4.22.-;
DE   AltName: Full=AUT-like 3 cysteine endopeptidase;
DE   AltName: Full=Autophagin-3;
DE   AltName: Full=Autophagy-related cysteine endopeptidase 3;
DE   AltName: Full=Autophagy-related protein 4 homolog C;
GN   Name=ATG4C; Synonyms=APG4C, AUTL1, AUTL3;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IGI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IGI:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   ATG4D_HUMAN             Reviewed;         474 AA.
AC   Q86TL0;
DE   RecName: Full=Cysteine protease ATG4D;
DE            EC=3.4.22.-;
DE   AltName: Full=AUT-like 4 cysteine endopeptidase;
DE   AltName: Full=Autophagin-4;
DE   AltName: Full=Autophagy-related cysteine endopeptidase 4;
DE   AltName: Full=Autophagy-related protein 4 homolog D;
DE   Contains:
DE     RecName: Full=Cysteine protease ATG4D, mitochondrial;
GN   Name=ATG4D; Synonyms=APG4D, AUTL4;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   ATG5_HUMAN              Reviewed;         275 AA.
AC   Q9H1Y0; O60875; Q5JVR2; Q68DI4; Q9H2B8; Q9HCZ7;
DE   RecName: Full=Autophagy protein 5;
DE   AltName: Full=APG5-like;
DE   AltName: Full=Apoptosis-specific protein;
GN   Name=ATG5; Synonyms=APG5L, ASP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000045; P:autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:0006914; P:autophagy; ISS:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0060047; P:heart contraction; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0048840; P:otolith development; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; ISS:UniProtKB.
DR   GO; GO:1902017; P:regulation of cilium assembly; ISS:UniProtKB.
DR   GO; GO:0002739; P:regulation of cytokine secretion involved in immune response; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009620; P:response to fungus; IEA:Ensembl.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
//
ID   ATG7_HUMAN              Reviewed;         703 AA.
AC   O95352; B4E170; E9PB95; Q7L8L0; Q9BWP2; Q9UFH4;
DE   RecName: Full=Ubiquitin-like modifier-activating enzyme ATG7;
DE   AltName: Full=ATG12-activating enzyme E1 ATG7;
DE   AltName: Full=Autophagy-related protein 7;
DE            Short=APG7-like;
DE            Short=hAGP7;
DE   AltName: Full=Ubiquitin-activating enzyme E1-like protein;
GN   Name=ATG7; Synonyms=APG7L;
DR   GO; GO:0019778; F:APG12 activating enzyme activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004839; F:ubiquitin activating enzyme activity; TAS:ProtInc.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:Ensembl.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0021955; P:central nervous system neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0050877; P:neurological system process; IEA:Ensembl.
DR   GO; GO:0006996; P:organelle organization; IEA:Ensembl.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0031401; P:positive regulation of protein modification process; IDA:MGI.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006497; P:protein lipidation; IDA:MGI.
DR   GO; GO:0032446; P:protein modification by small protein conjugation; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0021860; P:pyramidal neuron development; IEA:Ensembl.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
//
ID   ATG9A_HUMAN             Reviewed;         839 AA.
AC   Q7Z3C6; Q3ZAQ6; Q6P0N7; Q7Z317; Q7Z320; Q8NDK6; Q8WU65; Q9BVL5;
AC   Q9H6L1; Q9HAG7;
DE   RecName: Full=Autophagy-related protein 9A;
DE   AltName: Full=APG9-like 1;
DE   AltName: Full=mATG9;
GN   Name=ATG9A; Synonyms=APG9L1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:MGI.
DR   GO; GO:0045087; P:innate immune response; IEA:Ensembl.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   ATG9B_HUMAN             Reviewed;         924 AA.
AC   Q674R7; A1A5D3; Q6JRW5; Q8N8I8;
DE   RecName: Full=Autophagy-related protein 9B;
DE   AltName: Full=APG9-like 2;
DE   AltName: Full=Nitric oxide synthase 3-overlapping antisense gene protein;
DE            Short=Protein sONE;
GN   Name=ATG9B; Synonyms=APG9L2, NOS3AS;
DR   GO; GO:0000045; P:autophagic vacuole assembly; IDA:MGI.
//
ID   ATGA1_HUMAN             Reviewed;         218 AA.
AC   Q9BSB4; Q9HAE2; Q9HBN1;
DE   RecName: Full=Autophagy-related protein 101;
GN   Name=ATG101; Synonyms=C12orf44; ORFNames=PP894;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.
//
ID   ATHL1_HUMAN             Reviewed;         737 AA.
AC   Q32M88; Q658X8; Q8TEG9; Q9H635;
DE   RecName: Full=Acid trehalase-like protein 1;
DE            EC=3.2.1.-;
GN   Name=ATHL1;
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   ATIF1_HUMAN             Reviewed;         106 AA.
AC   Q9UII2; Q5JXL8; Q6IAQ7; Q9BSL9;
DE   RecName: Full=ATPase inhibitor, mitochondrial;
DE   AltName: Full=Inhibitor of F(1)F(o)-ATPase;
DE            Short=IF(1);
DE            Short=IF1;
DE   Flags: Precursor;
GN   Name=ATPIF1; Synonyms=ATPI;
DR   GO; GO:0043532; F:angiostatin binding; IDA:UniProtKB.
DR   GO; GO:0051117; F:ATPase binding; IDA:UniProtKB.
DR   GO; GO:0042030; F:ATPase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; ISS:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; TAS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006783; P:heme biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051346; P:negative regulation of hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0045980; P:negative regulation of nucleotide metabolic process; IEA:InterPro.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
//
ID   ATL1_HUMAN              Reviewed;        1762 AA.
AC   Q8N6G6; A6PVN1; A8K7E1; Q496M6; Q496M8; Q5T708; Q5VZT8; Q8NAI9;
AC   Q96RW4; Q9BXY3;
DE   RecName: Full=ADAMTS-like protein 1;
DE            Short=ADAMTSL-1;
DE   AltName: Full=Punctin-1;
DE   Flags: Precursor;
GN   Name=ADAMTSL1; Synonyms=ADAMTSR1, C9orf94; ORFNames=UNQ528/PRO1071;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATL2_HUMAN              Reviewed;         951 AA.
AC   Q86TH1; B1B0D5; O60345;
DE   RecName: Full=ADAMTS-like protein 2;
DE            Short=ADAMTSL-2;
DE   Flags: Precursor;
GN   Name=ADAMTSL2; Synonyms=KIAA0605;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
//
ID   ATL3_HUMAN              Reviewed;        1691 AA.
AC   P82987; A1A566; A1A567; Q9ULI7;
DE   RecName: Full=ADAMTS-like protein 3;
DE            Short=ADAMTSL-3;
DE   AltName: Full=Punctin-2;
DE   Flags: Precursor;
GN   Name=ADAMTSL3; Synonyms=KIAA1233;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATL4_HUMAN              Reviewed;        1074 AA.
AC   Q6UY14; Q5T5F7; Q6IPM6; Q8N643; Q9HBS6;
DE   RecName: Full=ADAMTS-like protein 4;
DE            Short=ADAMTSL-4;
DE   AltName: Full=Thrombospondin repeat-containing protein 1;
DE   Flags: Precursor;
GN   Name=ADAMTSL4; Synonyms=TSRC1; ORFNames=PP1396, UNQ2803/PRO34012;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
//
ID   ATL5_HUMAN              Reviewed;         481 AA.
AC   Q6ZMM2; B4DXK7; Q8IW95;
DE   RecName: Full=ADAMTS-like protein 5;
DE            Short=ADAMTSL-5;
DE   AltName: Full=Thrombospondin type-1 domain-containing protein 6;
DE   Flags: Precursor;
GN   Name=ADAMTSL5; Synonyms=THSD6;
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATLA1_HUMAN             Reviewed;         558 AA.
AC   Q8WXF7; A6NND5; A8K2C0; G5E9T1; O95890; Q69YH7; Q96FK0;
DE   RecName: Full=Atlastin-1;
DE            EC=3.6.5.-;
DE   AltName: Full=Brain-specific GTP-binding protein;
DE   AltName: Full=GTP-binding protein 3;
DE            Short=GBP-3;
DE            Short=hGBP3;
DE   AltName: Full=Guanine nucleotide-binding protein 3;
DE   AltName: Full=Spastic paraplegia 3 protein A;
GN   Name=ATL1; Synonyms=GBP3, SPG3A;
DR   GO; GO:0005525; F:GTP binding; ISS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   ATLA2_HUMAN             Reviewed;         583 AA.
AC   Q8NHH9; B7Z1X2; B7Z7X8; Q4ZG30; Q7Z630; Q8NHH8; Q9H5M7;
DE   RecName: Full=Atlastin-2;
DE            EC=3.6.5.-;
DE   AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 2;
DE            Short=ARL-6-interacting protein 2;
DE            Short=Aip-2;
GN   Name=ATL2; Synonyms=ARL6IP2;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   ATLA3_HUMAN             Reviewed;         541 AA.
AC   Q6DD88; Q8N7W5; Q9H8Q5; Q9UFL1;
DE   RecName: Full=Atlastin-3;
DE            EC=3.6.5.-;
GN   Name=ATL3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   ATMIN_HUMAN             Reviewed;         823 AA.
AC   O43313; A8K4H8; Q68DC9;
DE   RecName: Full=ATM interactor;
DE   AltName: Full=ATM/ATR-substrate CHK2-interacting zinc finger protein;
DE            Short=ASCIZ;
DE   AltName: Full=Zinc finger protein 822;
GN   Name=ATMIN; Synonyms=KIAA0431, ZNF822;
DR   GO; GO:0045502; F:dynein binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATM_HUMAN               Reviewed;        3056 AA.
AC   Q13315; B2RNX5; O15429; Q12758; Q16551; Q93007; Q9NP02; Q9UCX7;
DE   RecName: Full=Serine-protein kinase ATM;
DE            EC=2.7.11.1;
DE   AltName: Full=Ataxia telangiectasia mutated;
DE            Short=A-T mutated;
GN   Name=ATM;
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004677; F:DNA-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0035174; F:histone serine kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:BHF-UCL.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:BHF-UCL.
DR   GO; GO:0047485; F:protein N-terminus binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IDA:BHF-UCL.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0042159; P:lipoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; IMP:GOC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0090399; P:replicative senescence; IMP:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0072434; P:signal transduction involved in mitotic G2 DNA damage checkpoint; IMP:BHF-UCL.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   ATN1_HUMAN              Reviewed;        1190 AA.
AC   P54259; Q99495; Q99621; Q9UEK7;
DE   RecName: Full=Atrophin-1;
DE   AltName: Full=Dentatorubral-pallidoluysian atrophy protein;
GN   Name=ATN1; Synonyms=D12S755E, DRPLA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0030011; P:maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0009404; P:toxin metabolic process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATNG_HUMAN              Reviewed;          66 AA.
AC   P54710; Q15332; Q53YC1; Q9GZP3; Q9GZQ7;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit gamma;
DE            Short=Na(+)/K(+) ATPase subunit gamma;
DE   AltName: Full=FXYD domain-containing ion transport regulator 2;
DE   AltName: Full=Sodium pump gamma chain;
GN   Name=FXYD2; Synonyms=ATP1C, ATP1G1;
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0005391; F:sodium:potassium-exchanging ATPase activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ATOH1_HUMAN             Reviewed;         354 AA.
AC   Q92858; Q14CT9;
DE   RecName: Full=Protein atonal homolog 1;
DE   AltName: Full=Class A basic helix-loop-helix protein 14;
DE            Short=bHLHa14;
DE   AltName: Full=Helix-loop-helix protein hATH-1;
DE            Short=hATH1;
GN   Name=ATOH1; Synonyms=ATH1, BHLHA14;
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0042668; P:auditory receptor cell fate determination; IEA:Ensembl.
DR   GO; GO:0042667; P:auditory receptor cell fate specification; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045609; P:positive regulation of auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ATOH7_HUMAN             Reviewed;         152 AA.
AC   Q8N100;
DE   RecName: Full=Protein atonal homolog 7;
DE   AltName: Full=Class A basic helix-loop-helix protein 13;
DE            Short=bHLHa13;
DE   AltName: Full=Helix-loop-helix protein hATH-5;
DE            Short=hATH5;
GN   Name=ATOH7; Synonyms=ATH5, BHLHA13;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0009649; P:entrainment of circadian clock; IEA:Ensembl.
DR   GO; GO:0003407; P:neural retina development; IMP:MGI.
DR   GO; GO:0021554; P:optic nerve development; IMP:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATOH8_HUMAN             Reviewed;         321 AA.
AC   Q96SQ7; Q504S2; Q659B0;
DE   RecName: Full=Protein atonal homolog 8;
DE   AltName: Full=Class A basic helix-loop-helix protein 21;
DE            Short=bHLHa21;
DE   AltName: Full=Helix-loop-helix protein hATH-6;
DE            Short=hATH6;
GN   Name=ATOH8; Synonyms=ATH6, BHLHA21;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATOX1_HUMAN             Reviewed;          68 AA.
AC   O00244; A8KAJ8; D3DQI2; Q2M1R6; Q56AP3;
DE   RecName: Full=Copper transport protein ATOX1;
DE   AltName: Full=Metal transport protein ATX1;
GN   Name=ATOX1; Synonyms=HAH1;
DR   GO; GO:0016531; F:copper chaperone activity; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0032767; F:copper-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0016530; F:metallochaperone activity; TAS:UniProtKB.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006825; P:copper ion transport; TAS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
//
ID   ATP23_HUMAN             Reviewed;         246 AA.
AC   Q9Y6H3; Q1RLM4; Q96E81;
DE   RecName: Full=Mitochondrial inner membrane protease ATP23 homolog;
DE            EC=3.4.24.-;
DE   AltName: Full=Ku70-binding protein 3;
DE   AltName: Full=XRCC6-binding protein 1;
GN   Name=XRCC6BP1; Synonyms=KUB3;
DR   GO; GO:0004677; F:DNA-dependent protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:GOC.
//
ID   ATP4A_HUMAN             Reviewed;        1035 AA.
AC   P20648; O00738;
DE   RecName: Full=Potassium-transporting ATPase alpha chain 1;
DE            EC=3.6.3.10;
DE   AltName: Full=Gastric H(+)/K(+) ATPase subunit alpha;
DE   AltName: Full=Proton pump;
GN   Name=ATP4A;
DR   GuidetoPHARMACOLOGY; 849; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; TAS:ProtInc.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045851; P:pH reduction; IEA:Ensembl.
DR   GO; GO:0010155; P:regulation of proton transport; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ATP4B_HUMAN             Reviewed;         291 AA.
AC   P51164; B1B0N8;
DE   RecName: Full=Potassium-transporting ATPase subunit beta;
DE   AltName: Full=Gastric H(+)/K(+) ATPase subunit beta;
DE   AltName: Full=Proton pump beta chain;
GN   Name=ATP4B;
DR   GO; GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ATP5H_HUMAN             Reviewed;         161 AA.
AC   O75947; B2R5L6; Q9H3J4;
DE   RecName: Full=ATP synthase subunit d, mitochondrial;
DE            Short=ATPase subunit d;
GN   Name=ATP5H; ORFNames=My032;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATP5E_HUMAN             Reviewed;          51 AA.
AC   P56381; B2RDD0; E1P5H6; Q53XU6;
DE   RecName: Full=ATP synthase subunit epsilon, mitochondrial;
DE            Short=ATPase subunit epsilon;
GN   Name=ATP5E;
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATP5I_HUMAN             Reviewed;          69 AA.
AC   P56385; Q0D2L9;
DE   RecName: Full=ATP synthase subunit e, mitochondrial;
DE            Short=ATPase subunit e;
GN   Name=ATP5I; Synonyms=ATP5K;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATP5S_HUMAN             Reviewed;         215 AA.
AC   Q99766; A8K1U3; D9N156; Q8WWX3; Q96F77;
DE   RecName: Full=ATP synthase subunit s, mitochondrial;
DE   AltName: Full=ATP synthase-coupling factor B;
DE            Short=FB;
DE   AltName: Full=Mitochondrial ATP synthase regulatory component factor B;
DE   Flags: Precursor;
GN   Name=ATP5S; Synonyms=ATPW;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; NAS:GOC.
DR   GO; GO:0015992; P:proton transport; NAS:UniProtKB.
//
ID   ATP5L_HUMAN             Reviewed;         103 AA.
AC   O75964; A8K0K3; Q96BV6; Q9UBZ7;
DE   RecName: Full=ATP synthase subunit g, mitochondrial;
DE            Short=ATPase subunit g;
GN   Name=ATP5L;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATP5J_HUMAN             Reviewed;         108 AA.
AC   P18859; J3KQ83;
DE   RecName: Full=ATP synthase-coupling factor 6, mitochondrial;
DE            Short=ATPase subunit F6;
DE   Flags: Precursor;
GN   Name=ATP5J; Synonyms=ATP5A, ATPM;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   ATP6_HUMAN              Reviewed;         226 AA.
AC   P00846; Q34772; Q5S8W5; Q5S9E7; Q5S9I6; Q5SA31; Q6RPB7; Q6VHC0;
AC   Q6VHE0; Q6WQF4; Q7YCC1; Q7YCF8; Q7YCG1; Q85KU8; Q85KX1; Q85L05;
AC   Q8HNQ4; Q8HNQ8; Q8WCX6; Q9B2U5; Q9B2Z2;
DE   RecName: Full=ATP synthase subunit a;
DE   AltName: Full=F-ATPase protein 6;
GN   Name=MT-ATP6; Synonyms=ATP6, ATPASE6, MTATP6;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATP7A_HUMAN             Reviewed;        1500 AA.
AC   Q04656; B1AT72; O00227; O00745; Q9BYY8;
DE   RecName: Full=Copper-transporting ATPase 1;
DE            EC=3.6.3.54;
DE   AltName: Full=Copper pump 1;
DE   AltName: Full=Menkes disease-associated protein;
GN   Name=ATP7A; Synonyms=MC1, MNK;
DR   GO; GO:0005524; F:ATP binding; TAS:HGNC.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0005375; F:copper ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0032767; F:copper-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0004008; F:copper-exporting ATPase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016532; F:superoxide dismutase copper chaperone activity; ISS:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; ISS:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; ISS:UniProtKB.
DR   GO; GO:0006584; P:catecholamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0021954; P:central nervous system neuron development; ISS:UniProtKB.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030199; P:collagen fibril organization; ISS:UniProtKB.
DR   GO; GO:0060003; P:copper ion export; ISS:UniProtKB.
DR   GO; GO:0015677; P:copper ion import; ISS:UniProtKB.
DR   GO; GO:0006825; P:copper ion transport; IMP:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0010273; P:detoxification of copper ion; ISS:UniProtKB.
DR   GO; GO:0042417; P:dopamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0048251; P:elastic fiber assembly; ISS:UniProtKB.
DR   GO; GO:0051542; P:elastin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0042414; P:epinephrine metabolic process; ISS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; ISS:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0048286; P:lung alveolus development; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0048553; P:negative regulation of metalloenzyme activity; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042421; P:norepinephrine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042415; P:norepinephrine metabolic process; ISS:UniProtKB.
DR   GO; GO:0018205; P:peptidyl-lysine modification; ISS:UniProtKB.
DR   GO; GO:0043473; P:pigmentation; ISS:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; ISS:UniProtKB.
DR   GO; GO:0048554; P:positive regulation of metalloenzyme activity; ISS:UniProtKB.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0021860; P:pyramidal neuron development; ISS:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0002082; P:regulation of oxidative phosphorylation; ISS:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0019430; P:removal of superoxide radicals; ISS:UniProtKB.
DR   GO; GO:0010041; P:response to iron(III) ion; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0042428; P:serotonin metabolic process; ISS:UniProtKB.
DR   GO; GO:0043588; P:skin development; ISS:UniProtKB.
DR   GO; GO:0042093; P:T-helper cell differentiation; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006568; P:tryptophan metabolic process; ISS:UniProtKB.
DR   GO; GO:0006570; P:tyrosine metabolic process; IEA:Ensembl.
//
ID   ATP7B_HUMAN             Reviewed;        1465 AA.
AC   P35670; Q16318; Q16319; Q4U3V3; Q59FJ9; Q5T7X7;
DE   RecName: Full=Copper-transporting ATPase 2;
DE            EC=3.6.3.54;
DE   AltName: Full=Copper pump 2;
DE   AltName: Full=Wilson disease-associated protein;
DE   Contains:
DE     RecName: Full=WND/140 kDa;
GN   Name=ATP7B; Synonyms=PWD, WC1, WND;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0004008; F:copper-exporting ATPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IEA:Ensembl.
DR   GO; GO:0015677; P:copper ion import; IDA:UniProtKB.
DR   GO; GO:0006825; P:copper ion transport; IGI:UniProtKB.
DR   GO; GO:0015680; P:intracellular copper ion transport; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0046688; P:response to copper ion; IDA:UniProtKB.
DR   GO; GO:0051208; P:sequestering of calcium ion; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ATP8_HUMAN              Reviewed;          68 AA.
AC   P03928; Q34771;
DE   RecName: Full=ATP synthase protein 8;
DE   AltName: Full=A6L;
DE   AltName: Full=F-ATPase subunit 8;
GN   Name=MT-ATP8; Synonyms=ATP8, ATPASE8, MTATP8;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATP9A_HUMAN             Reviewed;        1047 AA.
AC   O75110; E1P5Y3; E1P5Y4; Q5TFW5; Q5TFW6; Q5TFW9; Q6ZMF3; Q9NQK6;
AC   Q9NQK7;
DE   RecName: Full=Probable phospholipid-transporting ATPase IIA;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class II type 9A;
GN   Name=ATP9A; Synonyms=ATPIIA, KIAA0611;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
//
ID   ATP9B_HUMAN             Reviewed;        1147 AA.
AC   O43861; O60872; Q08AD8; Q08AD9;
DE   RecName: Full=Probable phospholipid-transporting ATPase IIB;
DE            EC=3.6.3.1;
DE   AltName: Full=ATPase class II type 9B;
GN   Name=ATP9B; Synonyms=ATPIIB, NEO1L; ORFNames=HUSSY-20;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004012; F:phospholipid-translocating ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0072600; P:establishment of protein localization to Golgi; IMP:UniProtKB.
DR   GO; GO:0045332; P:phospholipid translocation; NAS:UniProtKB.
//
ID   ATPA_HUMAN              Reviewed;         553 AA.
AC   P25705; A8K092; B4DY56; K7ENP3; Q53XX6; Q8IXV2; Q96FB4; Q96HW2;
AC   Q96IR6; Q9BTV8;
DE   RecName: Full=ATP synthase subunit alpha, mitochondrial;
DE   Flags: Precursor;
GN   Name=ATP5A1; Synonyms=ATP5A, ATP5AL2, ATPM;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; ISS:UniProtKB.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATPB_HUMAN              Reviewed;         529 AA.
AC   P06576; A8K4X0; Q14283;
DE   RecName: Full=ATP synthase subunit beta, mitochondrial;
DE            EC=3.6.3.14;
DE   Flags: Precursor;
GN   Name=ATP5B; Synonyms=ATPMB, ATPSB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IMP:UniProtKB.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IMP:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; NAS:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IEA:Ensembl.
DR   GO; GO:0015992; P:proton transport; IMP:UniProtKB.
DR   GO; GO:0051453; P:regulation of intracellular pH; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATPD_HUMAN              Reviewed;         168 AA.
AC   P30049; D6W5Y3; Q6FG90;
DE   RecName: Full=ATP synthase subunit delta, mitochondrial;
DE   AltName: Full=F-ATPase delta subunit;
DE   Flags: Precursor;
GN   Name=ATP5D;
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; NAS:UniProtKB.
DR   GO; GO:0006119; P:oxidative phosphorylation; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0046688; P:response to copper ion; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATPF1_HUMAN             Reviewed;         328 AA.
AC   Q5TC12; B1AQW7; B7Z7D6; B7Z7I6; Q9H6E3;
DE   RecName: Full=ATP synthase mitochondrial F1 complex assembly factor 1;
DE   AltName: Full=ATP11 homolog;
DE   Flags: Precursor;
GN   Name=ATPAF1; Synonyms=ATP11;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IEA:InterPro.
//
ID   ATPF2_HUMAN             Reviewed;         289 AA.
AC   Q8N5M1; A6NDE5; A8K2J2; Q6XYC7;
DE   RecName: Full=ATP synthase mitochondrial F1 complex assembly factor 2;
DE   AltName: Full=ATP12 homolog;
DE   Flags: Precursor;
GN   Name=ATPAF2; Synonyms=ATP12; ORFNames=LP3663;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043461; P:proton-transporting ATP synthase complex assembly; NAS:UniProtKB.
//
ID   ATPG_HUMAN              Reviewed;         298 AA.
AC   P36542; A8KA31; Q5VYP3; Q6I9V2; Q96AS8;
DE   RecName: Full=ATP synthase subunit gamma, mitochondrial;
DE   AltName: Full=F-ATPase gamma subunit;
DE   Flags: Precursor;
GN   Name=ATP5C1; Synonyms=ATP5C, ATP5CL1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0006119; P:oxidative phosphorylation; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATPK_HUMAN              Reviewed;          94 AA.
AC   P56134; C9J8H9; F8W7V3; O76079; Q6IBB3; Q96L83; Q9BTI8;
DE   RecName: Full=ATP synthase subunit f, mitochondrial;
GN   Name=ATP5J2; Synonyms=ATP5JL;
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IC:UniProtKB.
DR   GO; GO:0015992; P:proton transport; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATPOS_HUMAN             Reviewed;          95 AA.
AC   Q5TC04;
DE   RecName: Full=Putative uncharacterized protein ATP1A1OS;
DE   AltName: Full=ATP1A1 opposite strand protein;
GN   Name=ATP1A1OS; Synonyms=C1orf203;
//
ID   ATPUN_HUMAN             Reviewed;         121 AA.
AC   Q6ZP68;
DE   RecName: Full=Putative protein ATP11AUN;
DE   AltName: Full=Putative ATP11A upstream neighbor protein;
GN   Name=ATP11AUN; Synonyms=C13orf35;
//
ID   ATPO_HUMAN              Reviewed;         213 AA.
AC   P48047; B2R4E2; Q5U042; Q6IBI2;
DE   RecName: Full=ATP synthase subunit O, mitochondrial;
DE   AltName: Full=Oligomycin sensitivity conferral protein;
DE            Short=OSCP;
DE   Flags: Precursor;
GN   Name=ATP5O; Synonyms=ATPO;
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IC:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0006754; P:ATP biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IMP:UniProtKB.
DR   GO; GO:0015992; P:proton transport; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ATRAP_HUMAN             Reviewed;         159 AA.
AC   Q6RW13; A8MVQ5; Q5SNV4; Q5SNV5; Q96AC0; Q96PL4; Q9NRW9;
DE   RecName: Full=Type-1 angiotensin II receptor-associated protein;
DE   AltName: Full=AT1 receptor-associated protein;
GN   Name=AGTRAP; Synonyms=ATRAP;
DR   GO; GO:0004945; F:angiotensin type II receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   ATRIP_HUMAN             Reviewed;         791 AA.
AC   Q8WXE1; A8K6A3; A8K714; B2RCE7; B4DU92; B5MEB7; Q69YK9; Q8NHQ2;
AC   Q8WUG7; Q96CL3; Q9HA30;
DE   RecName: Full=ATR-interacting protein;
DE   AltName: Full=ATM and Rad3-related-interacting protein;
GN   Name=ATRIP; Synonyms=AGS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; TAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
//
ID   ATRN1_HUMAN             Reviewed;        1379 AA.
AC   Q5VV63; O60283; Q5JSE8; Q5T5Y9; Q6T256; Q6ZSN4; Q86WX2;
DE   RecName: Full=Attractin-like protein 1;
DE   Flags: Precursor;
GN   Name=ATRNL1; Synonyms=KIAA0534;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
//
ID   ATRN_HUMAN              Reviewed;        1429 AA.
AC   O75882; A8KAE5; O60295; O95414; Q3MIT3; Q5TDA2; Q5TDA4; Q5VYW3;
AC   Q9NTQ3; Q9NTQ4; Q9NU01; Q9NZ57; Q9NZ58; Q9UC75; Q9UDF5;
DE   RecName: Full=Attractin;
DE   AltName: Full=DPPT-L;
DE   AltName: Full=Mahogany homolog;
DE   Flags: Precursor;
GN   Name=ATRN; Synonyms=KIAA0548, MGCA;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
//
ID   ATRX_HUMAN              Reviewed;        2492 AA.
AC   P46100; D3DTE2; P51068; Q15886; Q59FB5; Q59H31; Q5H9A2; Q5JWI4;
AC   Q7Z2J1; Q9H0Z1; Q9NTS3;
DE   RecName: Full=Transcriptional regulator ATRX;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase ATRX;
DE   AltName: Full=X-linked helicase II;
DE   AltName: Full=X-linked nuclear protein;
DE            Short=XNP;
DE   AltName: Full=Znf-HX;
GN   Name=ATRX; Synonyms=RAD54L, XH2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006306; P:DNA methylation; TAS:ProtInc.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
//
ID   ATR_HUMAN               Reviewed;        2644 AA.
AC   Q13535; Q59HB2; Q7KYL3; Q93051; Q9BXK4;
DE   RecName: Full=Serine/threonine-protein kinase ATR;
DE            EC=2.7.11.1;
DE   AltName: Full=Ataxia telangiectasia and Rad3-related protein;
DE   AltName: Full=FRAP-related protein 1;
GN   Name=ATR; Synonyms=FRP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0032405; F:MutLalpha complex binding; IDA:MGI.
DR   GO; GO:0032407; F:MutSalpha complex binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:UniProtKB.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IDA:BHF-UCL.
DR   GO; GO:0034644; P:cellular response to UV; IMP:BHF-UCL.
DR   GO; GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0090399; P:replicative senescence; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   ATS10_HUMAN             Reviewed;        1103 AA.
AC   Q9H324; M0QZE4;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 10;
DE            Short=ADAM-TS 10;
DE            Short=ADAM-TS10;
DE            Short=ADAMTS-10;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS10;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATS12_HUMAN             Reviewed;        1594 AA.
AC   P58397; A2RRN9; A5D6V6; Q6UWL3;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 12;
DE            Short=ADAM-TS 12;
DE            Short=ADAM-TS12;
DE            Short=ADAMTS-12;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS12; ORFNames=UNQ1918/PRO4389;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; IMP:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IDA:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:2001113; P:negative regulation of cellular response to hepatocyte growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:1902548; P:negative regulation of cellular response to vascular endothelial growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:1902203; P:negative regulation of hepatocyte growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030167; P:proteoglycan catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:1901509; P:regulation of endothelial tube morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; IDA:BHF-UCL.
//
ID   ATS13_HUMAN             Reviewed;        1427 AA.
AC   Q76LX8; Q6UY16; Q710F6; Q711T8; Q96L37; Q9H0G3;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13;
DE            Short=ADAM-TS 13;
DE            Short=ADAM-TS13;
DE            Short=ADAMTS-13;
DE            EC=3.4.24.87;
DE   AltName: Full=von Willebrand factor-cleaving protease;
DE            Short=vWF-CP;
DE            Short=vWF-cleaving protease;
DE   Flags: Precursor;
GN   Name=ADAMTS13; Synonyms=C9orf8; ORFNames=UNQ6102/PRO20085;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; TAS:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0009100; P:glycoprotein metabolic process; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0043171; P:peptide catabolic process; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
DR   GO; GO:0016485; P:protein processing; TAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0070670; P:response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
//
ID   ATS14_HUMAN             Reviewed;        1223 AA.
AC   Q8WXS8; Q5T4G0; Q5T4G1; Q8TE55; Q8TEY8;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 14;
DE            Short=ADAM-TS 14;
DE            Short=ADAM-TS14;
DE            Short=ADAMTS-14;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS14;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   ATS15_HUMAN             Reviewed;         950 AA.
AC   Q8TE58; Q32MI6;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 15;
DE            Short=ADAM-TS 15;
DE            Short=ADAM-TS15;
DE            Short=ADAMTS-15;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS15;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATS16_HUMAN             Reviewed;        1224 AA.
AC   Q8TE57; C6G490; Q8IVE2;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 16;
DE            Short=ADAM-TS 16;
DE            Short=ADAM-TS16;
DE            Short=ADAMTS-16;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS16; Synonyms=KIAA2029;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATS17_HUMAN             Reviewed;        1095 AA.
AC   Q8TE56; Q2I7G4; Q6ZN75;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 17;
DE            Short=ADAM-TS 17;
DE            Short=ADAM-TS17;
DE            Short=ADAMTS-17;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS17;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATS18_HUMAN             Reviewed;        1221 AA.
AC   Q8TE60; Q6P4R5; Q6ZWJ9;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 18;
DE            Short=ADAM-TS 18;
DE            Short=ADAM-TS18;
DE            Short=ADAMTS-18;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS18; Synonyms=ADAMTS21;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
//
ID   ATS19_HUMAN             Reviewed;        1207 AA.
AC   Q8TE59;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 19;
DE            Short=ADAM-TS 19;
DE            Short=ADAM-TS19;
DE            Short=ADAMTS-19;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS19;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATS1_HUMAN              Reviewed;         967 AA.
AC   Q9UHI8; D3DSD5; Q9NSJ8; Q9P2K0; Q9UH83; Q9UP80;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 1;
DE            Short=ADAM-TS 1;
DE            Short=ADAM-TS1;
DE            Short=ADAMTS-1;
DE            EC=3.4.24.-;
DE   AltName: Full=METH-1;
DE   Flags: Precursor;
GN   Name=ADAMTS1; Synonyms=KIAA1346, METH1;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
//
ID   ATS20_HUMAN             Reviewed;        1910 AA.
AC   P59510; A6NNC9; J3QT00;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 20;
DE            Short=ADAM-TS 20;
DE            Short=ADAM-TS20;
DE            Short=ADAMTS-20;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS20;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045636; P:positive regulation of melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IEA:Ensembl.
//
ID   ATS2_HUMAN              Reviewed;        1211 AA.
AC   O95450;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 2;
DE            Short=ADAM-TS 2;
DE            Short=ADAM-TS2;
DE            Short=ADAMTS-2;
DE            EC=3.4.24.14;
DE   AltName: Full=Procollagen I N-proteinase;
DE            Short=PC I-NP;
DE   AltName: Full=Procollagen I/II amino propeptide-processing enzyme;
DE   AltName: Full=Procollagen N-endopeptidase;
DE            Short=pNPI;
DE   Flags: Precursor;
GN   Name=ADAMTS2; Synonyms=PCINP, PCPNI;
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   ATS3_HUMAN              Reviewed;        1205 AA.
AC   O15072; A1L3U9; Q9BXZ8;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 3;
DE            Short=ADAM-TS 3;
DE            Short=ADAM-TS3;
DE            Short=ADAMTS-3;
DE            EC=3.4.24.-;
DE   AltName: Full=Procollagen II N-proteinase;
DE            Short=PC II-NP;
DE   AltName: Full=Procollagen II amino propeptide-processing enzyme;
DE   Flags: Precursor;
GN   Name=ADAMTS3; Synonyms=KIAA0366;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; NAS:UniProtKB.
DR   GO; GO:0030199; P:collagen fibril organization; NAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   ATS4_HUMAN              Reviewed;         837 AA.
AC   O75173; Q5VTW2; Q6P4Q8; Q6UWA8; Q9UN83;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 4;
DE            Short=ADAM-TS 4;
DE            Short=ADAM-TS4;
DE            Short=ADAMTS-4;
DE            EC=3.4.24.82;
DE   AltName: Full=ADMP-1;
DE   AltName: Full=Aggrecanase-1;
DE   Flags: Precursor;
GN   Name=ADAMTS4; Synonyms=KIAA0688; ORFNames=UNQ769/PRO1563;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   ATS5_HUMAN              Reviewed;         930 AA.
AC   Q9UNA0; Q52LV4; Q9UKP2;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 5;
DE            Short=ADAM-TS 5;
DE            Short=ADAM-TS5;
DE            Short=ADAMTS-5;
DE            EC=3.4.24.-;
DE   AltName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 11;
DE            Short=ADAM-TS 11;
DE            Short=ADAMTS-11;
DE   AltName: Full=ADMP-2;
DE   AltName: Full=Aggrecanase-2;
DE   Flags: Precursor;
GN   Name=ADAMTS5; Synonyms=ADAMTS11, ADMP2;
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   ATS6_HUMAN              Reviewed;        1117 AA.
AC   Q9UKP5; Q59EX6; Q5IR87; Q5IR88; Q5IR89; Q68DL1;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 6;
DE            Short=ADAM-TS 6;
DE            Short=ADAM-TS6;
DE            Short=ADAMTS-6;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS6;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ATS7_HUMAN              Reviewed;        1686 AA.
AC   Q9UKP4; Q14F51; Q6P7J9;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 7;
DE            Short=ADAM-TS 7;
DE            Short=ADAM-TS7;
DE            Short=ADAMTS-7;
DE            EC=3.4.24.-;
DE   AltName: Full=COMPase;
DE   Flags: Precursor;
GN   Name=ADAMTS7;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IDA:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:BHF-UCL.
//
ID   ATS8_HUMAN              Reviewed;         889 AA.
AC   Q9UP79; Q9NZS0;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 8;
DE            Short=ADAM-TS 8;
DE            Short=ADAM-TS8;
DE            Short=ADAMTS-8;
DE            EC=3.4.24.-;
DE   AltName: Full=METH-2;
DE   AltName: Full=METH-8;
DE   Flags: Precursor;
GN   Name=ADAMTS8; Synonyms=METH2;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0009673; F:low affinity phosphate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; TAS:GOC.
//
ID   ATS9_HUMAN              Reviewed;        1935 AA.
AC   Q9P2N4; A1L4L0; B7ZVX9; B9ZVN0; Q9NR29;
DE   RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 9;
DE            Short=ADAM-TS 9;
DE            Short=ADAM-TS9;
DE            Short=ADAMTS-9;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=ADAMTS9; Synonyms=KIAA1312;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006516; P:glycoprotein catabolic process; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045636; P:positive regulation of melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IDA:MGI.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ATTY_HUMAN              Reviewed;         454 AA.
AC   P17735; B2R8I1; D3DWS2;
DE   RecName: Full=Tyrosine aminotransferase;
DE            Short=TAT;
DE            EC=2.6.1.5;
DE   AltName: Full=L-tyrosine:2-oxoglutarate aminotransferase;
GN   Name=TAT;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004838; F:L-tyrosine:2-oxoglutarate aminotransferase activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IDA:UniProtKB.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0046689; P:response to mercury ion; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006572; P:tyrosine catabolic process; IDA:UniProtKB.
//
ID   ATX10_HUMAN             Reviewed;         475 AA.
AC   Q9UBB4; A6NLC4; B4DG05; O14998; O15009; Q6I9X4;
DE   RecName: Full=Ataxin-10;
DE   AltName: Full=Brain protein E46 homolog;
DE   AltName: Full=Spinocerebellar ataxia type 10 protein;
GN   Name=ATXN10; Synonyms=SCA10;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
//
ID   ATX1L_HUMAN             Reviewed;         689 AA.
AC   P0C7T5;
DE   RecName: Full=Ataxin-1-like;
DE   AltName: Full=Brother of ataxin-1;
DE            Short=Brother of ATXN1;
GN   Name=ATXN1L; Synonyms=BOAT, BOAT1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATX1_HUMAN              Reviewed;         815 AA.
AC   P54253; Q17S02; Q9UJG2; Q9Y4J1;
DE   RecName: Full=Ataxin-1;
DE   AltName: Full=Spinocerebellar ataxia type 1 protein;
GN   Name=ATXN1; Synonyms=ATX1, SCA1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0034046; F:poly(G) binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051168; P:nuclear export; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0006396; P:RNA processing; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   ATX2L_HUMAN             Reviewed;        1075 AA.
AC   Q8WWM7; A8K1R6; B9EGM2; E9PAR9; O95135; Q63ZY4; Q6NVJ8; Q6PJW6;
AC   Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q99703;
DE   RecName: Full=Ataxin-2-like protein;
DE   AltName: Full=Ataxin-2 domain protein;
DE   AltName: Full=Ataxin-2-related protein;
GN   Name=ATXN2L; Synonyms=A2D, A2LG, A2LP, A2RP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010603; P:regulation of cytoplasmic mRNA processing body assembly; IDA:UniProtKB.
DR   GO; GO:0034063; P:stress granule assembly; IMP:UniProtKB.
//
ID   ATX2_HUMAN              Reviewed;        1313 AA.
AC   Q99700; A6NLD4; Q6ZQZ7; Q99493;
DE   RecName: Full=Ataxin-2;
DE   AltName: Full=Spinocerebellar ataxia type 2 protein;
DE   AltName: Full=Trinucleotide repeat-containing gene 13 protein;
GN   Name=ATXN2; Synonyms=ATX2, SCA2, TNRC13;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:UniProtKB.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0002091; P:negative regulation of receptor internalization; IMP:UniProtKB.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; NAS:UniProtKB.
DR   GO; GO:0050658; P:RNA transport; NAS:UniProtKB.
DR   GO; GO:0034063; P:stress granule assembly; IMP:UniProtKB.
//
ID   ATX3L_HUMAN             Reviewed;         355 AA.
AC   Q9H3M9; B2RNY8;
DE   RecName: Full=Putative ataxin-3-like protein;
DE            EC=3.4.19.12;
DE   AltName: Full=Machado-Joseph disease protein 1-like;
GN   Name=ATXN3L; Synonyms=ATX3L, MJDL;
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATX3_HUMAN              Reviewed;         364 AA.
AC   P54252; A7LFZ5; D6RDL9; E9PB63; O15284; O15285; O15286; Q8N189;
AC   Q96TC3; Q96TC4; Q9H3N0;
DE   RecName: Full=Ataxin-3;
DE            EC=3.4.19.12;
DE   AltName: Full=Machado-Joseph disease protein 1;
DE   AltName: Full=Spinocerebellar ataxia type 3 protein;
GN   Name=ATXN3; Synonyms=ATX3, MJD, MJD1, SCA3;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:MGI.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071218; P:cellular response to misfolded protein; ISS:UniProtKB.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IMP:MGI.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0035520; P:monoubiquitinated protein deubiquitination; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:ProtInc.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0010810; P:regulation of cell-substrate adhesion; IMP:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ATX7_HUMAN              Reviewed;         892 AA.
AC   O15265; B4E207; E9PHP9; O75328; O75329; Q9Y6P8;
DE   RecName: Full=Ataxin-7;
DE   AltName: Full=Spinocerebellar ataxia type 7 protein;
GN   Name=ATXN7; Synonyms=SCA7;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0006997; P:nucleus organization; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   ATX8_HUMAN              Reviewed;          80 AA.
AC   Q156A1;
DE   RecName: Full=Ataxin-8;
DE   AltName: Full=Protein 1C2;
GN   Name=ATXN8;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   AUGN_HUMAN              Reviewed;         148 AA.
AC   Q9H1Z8; D3DVK2;
DE   RecName: Full=Augurin;
DE   AltName: Full=Esophageal cancer-related gene 4 protein;
DE   Flags: Precursor;
GN   Name=C2orf40; Synonyms=ECRG4; ORFNames=UNQ761/PRO1508;
DR   GO; GO:0090398; P:cellular senescence; IEA:Ensembl.
DR   GO; GO:0008054; P:cyclin catabolic process; IEA:Ensembl.
DR   GO; GO:0070314; P:G1 to G0 transition; IEA:Ensembl.
//
ID   AUHM_HUMAN              Reviewed;         339 AA.
AC   Q13825; B1ALV7; B1ALV8; Q8WUE4;
DE   RecName: Full=Methylglutaconyl-CoA hydratase, mitochondrial;
DE            EC=4.2.1.18;
DE   AltName: Full=AU-specific RNA-binding enoyl-CoA hydratase;
DE            Short=AU-binding protein/enoyl-CoA hydratase;
DE   Flags: Precursor;
GN   Name=AUH;
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; IDA:UniProtKB.
DR   GO; GO:0004490; F:methylglutaconyl-CoA hydratase activity; EXP:Reactome.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006552; P:leucine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   AUNIP_HUMAN             Reviewed;         357 AA.
AC   Q9H7T9; C9EI59; Q53F70;
DE   RecName: Full=Aurora kinase A and ninein-interacting protein;
DE            Short=AIBp;
GN   Name=AUNIP; Synonyms=C1orf135;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   AUP1_HUMAN              Reviewed;         476 AA.
AC   Q9Y679; C0H5W8; Q9H866; Q9UNQ6; Q9Y685;
DE   RecName: Full=Ancient ubiquitous protein 1;
GN   Name=AUP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   AURKA_HUMAN             Reviewed;         403 AA.
AC   O14965; E1P5F9; O60445; O75873; Q9BQD6; Q9UPG5;
DE   RecName: Full=Aurora kinase A;
DE            EC=2.7.11.1;
DE   AltName: Full=Aurora 2;
DE   AltName: Full=Aurora/IPL1-related kinase 1;
DE            Short=ARK-1;
DE            Short=Aurora-related kinase 1;
DE            Short=hARK1;
DE   AltName: Full=Breast tumor-amplified kinase;
DE   AltName: Full=Serine/threonine-protein kinase 15;
DE   AltName: Full=Serine/threonine-protein kinase 6;
DE   AltName: Full=Serine/threonine-protein kinase aurora-A;
GN   Name=AURKA;
GN   Synonyms=AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6;
DR   GuidetoPHARMACOLOGY; 1936; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; EXP:Reactome.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; TAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046605; P:regulation of centrosome cycle; TAS:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; NAS:UniProtKB.
DR   GO; GO:0043146; P:spindle stabilization; IMP:UniProtKB.
//
ID   AURKB_HUMAN             Reviewed;         344 AA.
AC   Q96GD4; B4DNM4; C7G533; C7G534; C7G535; D3DTR4; J9JID1; O14630;
AC   O60446; O95083; Q96DV5; Q9UQ46;
DE   RecName: Full=Aurora kinase B;
DE            EC=2.7.11.1;
DE   AltName: Full=Aurora 1;
DE   AltName: Full=Aurora- and IPL1-like midbody-associated protein 1;
DE            Short=AIM-1;
DE   AltName: Full=Aurora/IPL1-related kinase 2;
DE            Short=ARK-2;
DE            Short=Aurora-related kinase 2;
DE   AltName: Full=STK-1;
DE   AltName: Full=Serine/threonine-protein kinase 12;
DE   AltName: Full=Serine/threonine-protein kinase 5;
DE   AltName: Full=Serine/threonine-protein kinase aurora-B;
GN   Name=AURKB; Synonyms=AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5;
DR   GuidetoPHARMACOLOGY; 1937; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0036089; P:cleavage furrow formation; IDA:UniProtKB.
DR   GO; GO:0043988; P:histone H3-S28 phosphorylation; ISS:UniProtKB.
DR   GO; GO:0016570; P:histone modification; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0002903; P:negative regulation of B cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051983; P:regulation of chromosome segregation; TAS:UniProtKB.
DR   GO; GO:0031577; P:spindle checkpoint; IEA:InterPro.
DR   GO; GO:0051256; P:spindle midzone assembly involved in mitosis; IMP:UniProtKB.
DR   GO; GO:0043146; P:spindle stabilization; IMP:UniProtKB.
//
ID   AURKC_HUMAN             Reviewed;         309 AA.
AC   Q9UQB9; O60681; O75442; Q6AZY8; Q6DLZ0; Q9UPK5;
DE   RecName: Full=Aurora kinase C;
DE            EC=2.7.11.1;
DE   AltName: Full=Aurora 3;
DE   AltName: Full=Aurora/IPL1-related kinase 3;
DE            Short=ARK-3;
DE            Short=Aurora-related kinase 3;
DE   AltName: Full=Aurora/IPL1/Eg2 protein 2;
DE   AltName: Full=Serine/threonine-protein kinase 13;
DE   AltName: Full=Serine/threonine-protein kinase aurora-C;
GN   Name=AURKC; Synonyms=AIE2, AIK3, AIRK3, ARK3, STK13;
DR   GuidetoPHARMACOLOGY; 1938; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; TAS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:ProtInc.
DR   GO; GO:0016570; P:histone modification; TAS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051256; P:spindle midzone assembly involved in mitosis; TAS:UniProtKB.
//
ID   AUTS2_HUMAN             Reviewed;        1259 AA.
AC   Q8WXX7; A4D1Y9; Q5D049; Q6PJU5; Q9Y4F2;
DE   RecName: Full=Autism susceptibility gene 2 protein;
GN   Name=AUTS2; Synonyms=KIAA0442;
//
ID   AUXI_HUMAN              Reviewed;         913 AA.
AC   O75061; B7Z3V8; D3DQ65; D3DQ66; Q32M66; Q4G0K1; Q5T614; Q5T615;
DE   RecName: Full=Putative tyrosine-protein phosphatase auxilin;
DE            EC=3.1.3.48;
DE   AltName: Full=DnaJ homolog subfamily C member 6;
GN   Name=DNAJC6; Synonyms=KIAA0473;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
//
ID   AVEN_HUMAN              Reviewed;         362 AA.
AC   Q9NQS1;
DE   RecName: Full=Cell death regulator Aven;
GN   Name=AVEN;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
//
ID   AVIL_HUMAN              Reviewed;         819 AA.
AC   O75366; B2RAU7; Q2NKM9;
DE   RecName: Full=Advillin;
DE   AltName: Full=p92;
GN   Name=AVIL;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
//
ID   AVL9_HUMAN              Reviewed;         648 AA.
AC   Q8NBF6; Q92573;
DE   RecName: Full=Late secretory pathway protein AVL9 homolog;
GN   Name=AVL9; Synonyms=KIAA0241;
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
//
ID   AVPI1_HUMAN             Reviewed;         147 AA.
AC   Q5T686; Q53G32; Q9H2R9; Q9HBN9;
DE   RecName: Full=Arginine vasopressin-induced protein 1;
DE            Short=AVP-induced protein 1;
GN   Name=AVPI1; ORFNames=NPD013, PP5395;
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   AVR2A_HUMAN             Reviewed;         513 AA.
AC   P27037; B2RAB8; B4DWQ2; D3DP85; Q53TH4; Q6NWV2; Q92474;
DE   RecName: Full=Activin receptor type-2A;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor type IIA;
DE            Short=ACTR-IIA;
DE            Short=ACTRIIA;
DE   Flags: Precursor;
GN   Name=ACVR2A; Synonyms=ACVR2;
DR   GuidetoPHARMACOLOGY; 1791; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0015026; F:coreceptor activity; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; EXP:Reactome.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0004675; F:transmembrane receptor protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0043084; P:penile erection; IEA:Ensembl.
DR   GO; GO:0032927; P:positive regulation of activin receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:HGNC.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.
DR   GO; GO:0030510; P:regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0060011; P:Sertoli cell proliferation; IEA:Ensembl.
DR   GO; GO:0042713; P:sperm ejaculation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; TAS:ProtInc.
//
ID   AVR2B_HUMAN             Reviewed;         512 AA.
AC   Q13705; Q4VAV0;
DE   RecName: Full=Activin receptor type-2B;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor type IIB;
DE            Short=ACTR-IIB;
DE   Flags: Precursor;
GN   Name=ACVR2B;
DR   GuidetoPHARMACOLOGY; 1792; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019838; F:growth factor binding; IPI:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IMP:HGNC.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:Ensembl.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0032147; P:activation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0032924; P:activin receptor signaling pathway; TAS:GOC.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IMP:HGNC.
DR   GO; GO:0060840; P:artery development; ISS:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0001946; P:lymphangiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060836; P:lymphatic endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0032927; P:positive regulation of activin receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IDA:HGNC.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; TAS:ProtInc.
DR   GO; GO:0060841; P:venous blood vessel development; ISS:BHF-UCL.
//
ID   AWAT2_HUMAN             Reviewed;         333 AA.
AC   Q6E213; Q6IEE3; Q6P437;
DE   RecName: Full=Acyl-CoA wax alcohol acyltransferase 2;
DE            EC=2.3.1.75;
DE   AltName: Full=Acyl-CoA retinol O-fatty-acyltransferase;
DE            Short=ARAT;
DE            Short=Retinol O-fatty-acyltransferase;
DE            EC=2.3.1.76;
DE   AltName: Full=Diacylglycerol O-acyltransferase 2-like protein 4;
DE   AltName: Full=Diacylglycerol O-acyltransferase candidate 4;
DE            Short=hDC4;
DE   AltName: Full=Long-chain-alcohol O-fatty-acyltransferase 2;
DE   AltName: Full=Multifunctional O-acyltransferase;
DE   AltName: Full=Wax synthase;
DE            Short=hWS;
GN   Name=AWAT2; Synonyms=DC4, DGAT2L4, MFAT, WS;
DR   GO; GO:0047196; F:long-chain-alcohol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050252; F:retinol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010025; P:wax biosynthetic process; IEA:Ensembl.
//
ID   AWAT1_HUMAN             Reviewed;         328 AA.
AC   Q58HT5; Q5JT21; Q6IEE4;
DE   RecName: Full=Acyl-CoA wax alcohol acyltransferase 1;
DE            EC=2.3.1.75;
DE   AltName: Full=Diacylglycerol O-acyltransferase 2-like protein 3;
DE   AltName: Full=Diacylglycerol acyltransferase 2;
DE   AltName: Full=Long-chain-alcohol O-fatty-acyltransferase 1;
GN   Name=AWAT1; Synonyms=DGA2, DGAT2L3;
DR   GO; GO:0047196; F:long-chain-alcohol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
//
ID   AX2R_HUMAN              Reviewed;         193 AA.
AC   Q3ZCQ2; Q8NHX5;
DE   RecName: Full=Annexin-2 receptor;
DE   AltName: Full=Annexin II receptor;
DE            Short=AXIIR;
GN   Name=ANXA2R; Synonyms=AX2R, C5orf39;
//
ID   AXA2L_HUMAN             Reviewed;         339 AA.
AC   A6NMY6;
DE   RecName: Full=Putative annexin A2-like protein;
DE   AltName: Full=Annexin A2 pseudogene 2;
DE   AltName: Full=Lipocortin II pseudogene;
GN   Name=ANXA2P2; Synonyms=ANX2L2, ANX2P2, LPC2B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0004859; F:phospholipase inhibitor activity; IEA:InterPro.
//
ID   AXA81_HUMAN             Reviewed;         327 AA.
AC   Q5T2P8; A6NDE6; B4DKI1;
DE   RecName: Full=Annexin A8-like protein 1;
GN   Name=ANXA8L1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
//
ID   AXA82_HUMAN             Reviewed;         327 AA.
AC   Q5VT79; B2R939; Q53FY2; Q5VT78; Q96H89;
DE   RecName: Full=Annexin A8-like protein 2;
GN   Name=ANXA8L2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
//
ID   AXDN1_HUMAN             Reviewed;        1012 AA.
AC   Q5T1B0; Q6AWB2; Q96LJ3; Q96M01;
DE   RecName: Full=Axonemal dynein light chain domain-containing protein 1;
GN   Name=AXDND1; Synonyms=C1orf125;
//
ID   AXIN1_HUMAN             Reviewed;         862 AA.
AC   O15169; Q4TT26; Q4TT27; Q86YA7; Q8WVW6; Q96S28;
DE   RecName: Full=Axin-1;
DE   AltName: Full=Axis inhibition protein 1;
DE            Short=hAxin;
GN   Name=AXIN1; Synonyms=AXIN;
DR   GO; GO:0070016; F:armadillo repeat domain binding; ISS:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IDA:BHF-UCL.
DR   GO; GO:0046332; F:SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IBA:RefGenome.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0048320; P:axial mesoderm formation; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IC:UniProtKB.
DR   GO; GO:0060823; P:canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:RefGenome.
DR   GO; GO:0008219; P:cell death; IBA:RefGenome.
DR   GO; GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IBA:RefGenome.
DR   GO; GO:0007368; P:determination of left/right symmetry; IBA:RefGenome.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IBA:RefGenome.
DR   GO; GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IBA:RefGenome.
DR   GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:RefGenome.
DR   GO; GO:0071514; P:genetic imprinting; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0055001; P:muscle cell development; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IBA:RefGenome.
DR   GO; GO:0051248; P:negative regulation of protein metabolic process; IEA:Ensembl.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0030910; P:olfactory placode formation; IBA:RefGenome.
DR   GO; GO:0001743; P:optic placode formation; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; NAS:BHF-UCL.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; NAS:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; NAS:BHF-UCL.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:BHF-UCL.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0035412; P:regulation of catenin import into nucleus; IBA:RefGenome.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IBA:RefGenome.
DR   GO; GO:0021881; P:Wnt-activated signaling pathway involved in forebrain neuron fate commitment; IBA:RefGenome.
//
ID   AXIN2_HUMAN             Reviewed;         843 AA.
AC   Q9Y2T1; Q3MJ88; Q9H3M6; Q9UH84;
DE   RecName: Full=Axin-2;
DE   AltName: Full=Axin-like protein;
DE            Short=Axil;
DE   AltName: Full=Axis inhibition protein 2;
DE   AltName: Full=Conductin;
GN   Name=AXIN2;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IBA:RefGenome.
DR   GO; GO:0008013; F:beta-catenin binding; NAS:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0034613; P:cellular protein localization; IDA:BHF-UCL.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome.
DR   GO; GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IBA:RefGenome.
DR   GO; GO:0001957; P:intramembranous ossification; IBA:RefGenome.
DR   GO; GO:0043570; P:maintenance of DNA repeat elements; IMP:BHF-UCL.
DR   GO; GO:0048255; P:mRNA stabilization; IMP:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IBA:RefGenome.
DR   GO; GO:0042476; P:odontogenesis; IMP:BHF-UCL.
DR   GO; GO:0010942; P:positive regulation of cell death; IMP:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0070602; P:regulation of centromeric sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0061181; P:regulation of chondrocyte development; IEA:Ensembl.
DR   GO; GO:0032423; P:regulation of mismatch repair; IMP:BHF-UCL.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IBA:RefGenome.
//
ID   AZI2_HUMAN              Reviewed;         392 AA.
AC   Q9H6S1; A8K3M2; C9JB40; H7BXU6; Q86W99; Q9BQF1;
DE   RecName: Full=5-azacytidine-induced protein 2;
DE   AltName: Full=NF-kappa-B-activating kinase-associated protein 1;
DE            Short=Nak-associated protein 1;
DE   AltName: Full=TILP;
GN   Name=AZI2; Synonyms=NAP1, TBKBP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
//
ID   AZIN1_HUMAN             Reviewed;         448 AA.
AC   O14977; A6NCD5; Q6IBQ7; Q96D20;
DE   RecName: Full=Antizyme inhibitor 1;
DE            Short=AZI;
DE   AltName: Full=Ornithine decarboxylase antizyme inhibitor;
GN   Name=AZIN1; Synonyms=OAZI, OAZIN;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0042978; F:ornithine decarboxylase activator activity; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B2CL1_HUMAN             Reviewed;         233 AA.
AC   Q07817; E1P5L6; Q5CZ89; Q5TE65; Q92976;
DE   RecName: Full=Bcl-2-like protein 1;
DE            Short=Bcl2-L-1;
DE   AltName: Full=Apoptosis regulator Bcl-X;
GN   Name=BCL2L1; Synonyms=BCL2L, BCLX;
DR   GO; GO:0051434; F:BH3 domain binding; IPI:UniProt.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0071839; P:apoptotic process in bone marrow; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0060154; P:cellular process regulating host cell cycle in response to virus; IEA:Ensembl.
DR   GO; GO:0071312; P:cellular response to alkaloid; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:Ensembl.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:1900118; P:negative regulation of execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:BHF-UCL.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IC:BHF-UCL.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IDA:HGNC.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IDA:HGNC.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:HGNC.
DR   GO; GO:0046898; P:response to cycloheximide; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IDA:MGI.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0019050; P:suppression by virus of host apoptotic process; IDA:MGI.
//
ID   B2CL2_HUMAN             Reviewed;         193 AA.
AC   Q92843; A8K0F4; Q2M3U0; Q5U0H4;
DE   RecName: Full=Bcl-2-like protein 2;
DE            Short=Bcl2-L-2;
DE   AltName: Full=Apoptosis regulator Bcl-W;
GN   Name=BCL2L2; Synonyms=BCLW, KIAA0271;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IBA:RefGenome.
DR   GO; GO:0060011; P:Sertoli cell proliferation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   B2L10_HUMAN             Reviewed;         194 AA.
AC   Q9HD36; Q3SX80; Q52LQ9; Q8TCS9;
DE   RecName: Full=Bcl-2-like protein 10;
DE            Short=Bcl2-L-10;
DE   AltName: Full=Anti-apoptotic protein NrH;
DE   AltName: Full=Apoptosis regulator Bcl-B;
GN   Name=BCL2L10; Synonyms=BCLB;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:ProtInc.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:HGNC.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IBA:RefGenome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   B2L11_HUMAN             Reviewed;         198 AA.
AC   O43521; A8K2W2; O43522; Q0MSE7; Q0MSE8; Q0MSE9; Q53R28; Q6JTU6;
AC   Q6T851; Q6TE14; Q6TE15; Q6TE16; Q6V402; Q8WYL6; Q8WYL7; Q8WYL8;
AC   Q8WYL9; Q8WYM0; Q8WYM1;
DE   RecName: Full=Bcl-2-like protein 11;
DE            Short=Bcl2-L-11;
DE   AltName: Full=Bcl2-interacting mediator of cell death;
GN   Name=BCL2L11; Synonyms=BIM;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:1902263; P:apoptotic process involved in embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0001783; P:B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0060154; P:cellular process regulating host cell cycle in response to virus; IEA:Ensembl.
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0043583; P:ear development; IEA:Ensembl.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:MGI.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0002262; P:myeloid cell homeostasis; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0060139; P:positive regulation of apoptotic process by virus; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:1902110; P:positive regulation of mitochondrial membrane permeability involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0048563; P:post-embryonic organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0048070; P:regulation of developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0046620; P:regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0070242; P:thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0035148; P:tube formation; IEA:Ensembl.
//
ID   B2L12_HUMAN             Reviewed;         334 AA.
AC   Q9HB09; Q3SY11; Q3SY13; Q96I96; Q9HB08;
DE   RecName: Full=Bcl-2-like protein 12;
DE            Short=Bcl2-L-12;
DE   AltName: Full=Bcl-2-related proline-rich protein;
GN   Name=BCL2L12; Synonyms=BPR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:1990001; P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProt.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProt.
//
ID   B2L13_HUMAN             Reviewed;         485 AA.
AC   Q9BXK5; B3KPE7; Q96B37; Q96IB7; Q9BY01; Q9HC05; Q9UFE0; Q9UKN3;
DE   RecName: Full=Bcl-2-like protein 13;
DE            Short=Bcl2-L-13;
DE   AltName: Full=Bcl-rambo;
DE   AltName: Full=Protein Mil1;
GN   Name=BCL2L13; Synonyms=MIL1; ORFNames=CD003;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
//
ID   B2L14_HUMAN             Reviewed;         327 AA.
AC   Q9BZR8; A8KAD0; Q96QR5; Q9BZR7;
DE   RecName: Full=Apoptosis facilitator Bcl-2-like protein 14;
DE            Short=Bcl2-L-14;
DE   AltName: Full=Apoptosis regulator Bcl-G;
GN   Name=BCL2L14; Synonyms=BCLG;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   B2L15_HUMAN             Reviewed;         163 AA.
AC   Q5TBC7; A0PJY6; A8K074; I6LA82;
DE   RecName: Full=Bcl-2-like protein 15;
DE            Short=Bcl2-L-15;
GN   Name=BCL2L15; Synonyms=C1orf178;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   B2LA1_HUMAN             Reviewed;         175 AA.
AC   Q16548; Q6FGZ4; Q6FH19; Q86W13; Q99524;
DE   RecName: Full=Bcl-2-related protein A1;
DE   AltName: Full=Bcl-2-like protein 5;
DE            Short=Bcl2-L-5;
DE   AltName: Full=Hemopoietic-specific early response protein;
DE   AltName: Full=Protein BFL-1;
DE   AltName: Full=Protein GRS;
GN   Name=BCL2A1; Synonyms=BCL2L5, BFL1, GRS, HBPA1;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IBA:RefGenome.
//
ID   B2MG_HUMAN              Reviewed;         119 AA.
AC   P61769; P01884; Q540F8; Q6IAT8; Q9UCK0; Q9UD48; Q9UDF4;
DE   RecName: Full=Beta-2-microglobulin;
DE   Contains:
DE     RecName: Full=Beta-2-microglobulin form pI 5.3;
DE   Flags: Precursor;
GN   Name=B2M; ORFNames=CDABP0092, HDCMA22P;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002481; P:antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; IEA:Ensembl.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0042026; P:protein refolding; IEA:Ensembl.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   B3A2_HUMAN              Reviewed;        1241 AA.
AC   P04920; B2R6T0; B4DIT0; D3DX05; F8W682; Q45EY5; Q969L3;
DE   RecName: Full=Anion exchange protein 2;
DE            Short=AE 2;
DE            Short=Anion exchanger 2;
DE   AltName: Full=Non-erythroid band 3-like protein;
DE            Short=BND3L;
DE   AltName: Full=Solute carrier family 4 member 2;
GN   Name=SLC4A2; Synonyms=AE2, EPB3L1, HKB3, MPB3L;
DR   GO; GO:0008509; F:anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0006820; P:anion transport; TAS:ProtInc.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   B3A3_HUMAN              Reviewed;        1232 AA.
AC   P48751; A6H8L2; A8K1Q9; B7ZVX6; B9EGD1; Q6YIQ9;
DE   RecName: Full=Anion exchange protein 3;
DE            Short=AE 3;
DE            Short=Anion exchanger 3;
DE   AltName: Full=CAE3/BAE3;
DE   AltName: Full=Cardiac/brain band 3-like protein;
DE   AltName: Full=Neuronal band 3-like protein;
DE   AltName: Full=Solute carrier family 4 member 3;
GN   Name=SLC4A3; Synonyms=AE3;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; TAS:ProtInc.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0051453; P:regulation of intracellular pH; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   B3A4_HUMAN              Reviewed;         983 AA.
AC   Q96Q91; B7ZL63; D3DQD4; D3DQD5; D3DQD6; E9PDK1; Q96RM5; Q9BXF2;
AC   Q9BXN3;
DE   RecName: Full=Anion exchange protein 4;
DE            Short=AE 4;
DE            Short=Anion exchanger 4;
DE   AltName: Full=Sodium bicarbonate cotransporter 5;
DE   AltName: Full=Solute carrier family 4 member 9;
GN   Name=SLC4A9; Synonyms=AE4, SBC5;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   B3AT_HUMAN              Reviewed;         911 AA.
AC   P02730; G4V2I6; P78487; Q1ZZ45; Q4KKW9; Q4VB84; Q9UCY7; Q9UDJ1;
DE   RecName: Full=Band 3 anion transport protein;
DE   AltName: Full=Anion exchange protein 1;
DE            Short=AE 1;
DE            Short=Anion exchanger 1;
DE   AltName: Full=Solute carrier family 4 member 1;
DE   AltName: CD_antigen=CD233;
GN   Name=SLC4A1; Synonyms=AE1, DI, EPB3;
DR   GO; GO:0008509; F:anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015301; F:anion:anion antiporter activity; IDA:UniProtKB.
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0015106; F:bicarbonate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IDA:UniProtKB.
DR   GO; GO:0043495; F:protein anchor; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0006820; P:anion transport; IDA:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; IDA:UniProtKB.
DR   GO; GO:0006873; P:cellular ion homeostasis; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; ISS:GOC.
DR   GO; GO:0006821; P:chloride transport; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   B3GA1_HUMAN             Reviewed;         334 AA.
AC   Q9P2W7; Q96FS7;
DE   RecName: Full=Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1;
DE            EC=2.4.1.135;
DE   AltName: Full=Beta-1,3-glucuronyltransferase 1;
DE   AltName: Full=Glucuronosyltransferase P;
DE            Short=GlcAT-P;
DE   AltName: Full=UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase;
DE            Short=GlcUAT-P;
GN   Name=B3GAT1; Synonyms=GLCATP;
DR   GO; GO:0015018; F:galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GA2_HUMAN             Reviewed;         323 AA.
AC   Q9NPZ5; Q5JS09; Q8TF38; Q96NK4;
DE   RecName: Full=Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2;
DE            EC=2.4.1.135;
DE   AltName: Full=Beta-1,3-glucuronyltransferase 2;
DE   AltName: Full=GlcAT-D;
DE   AltName: Full=UDP-glucuronosyltransferase S;
DE            Short=GlcAT-S;
DE            Short=Glucuronosyltransferase S;
GN   Name=B3GAT2; Synonyms=GLCATS, KIAA1963;
DR   GO; GO:0015018; F:galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GA3_HUMAN             Reviewed;         335 AA.
AC   O94766; Q96I06; Q9UEP0;
DE   RecName: Full=Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3;
DE            EC=2.4.1.135;
DE   AltName: Full=Beta-1,3-glucuronyltransferase 3;
DE   AltName: Full=Glucuronosyltransferase I;
DE            Short=GlcAT-I;
DE   AltName: Full=UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase;
DE            Short=GlcUAT-I;
GN   Name=B3GAT3;
DR   GO; GO:0015018; F:galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IMP:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0050650; P:chondroitin sulfate proteoglycan biosynthetic process; IDA:MGI.
DR   GO; GO:0050651; P:dermatan sulfate proteoglycan biosynthetic process; IDA:MGI.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IDA:MGI.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GL1_HUMAN             Reviewed;         331 AA.
AC   O75752; D3DNM4; Q3Y531; Q6IAI5; Q8NFM8; Q8NFM9; Q9HA06;
DE   RecName: Full=UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1;
DE            Short=Beta-1,3-GalNAc-T1;
DE            EC=2.4.1.79;
DE   AltName: Full=Beta-1,3-galactosyltransferase 3;
DE            Short=Beta-1,3-GalTase 3;
DE            Short=Beta3Gal-T3;
DE            Short=Beta3GalT3;
DE            Short=b3Gal-T3;
DE   AltName: Full=Beta-3-Gx-T3;
DE   AltName: Full=Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase;
DE   AltName: Full=Globoside synthase;
DE   AltName: Full=UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase;
GN   Name=B3GALNT1; Synonyms=B3GALT3; ORFNames=UNQ531/PRO1074;
DR   GO; GO:0047273; F:galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   B3GL2_HUMAN             Reviewed;         500 AA.
AC   Q8NCR0; Q59GR3; Q5TCI3; Q96AL7;
DE   RecName: Full=UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2;
DE            Short=Beta-1,3-GalNAc-T2;
DE            EC=2.4.1.-;
DE   AltName: Full=Beta-1,3-N-acetylgalactosaminyltransferase II;
GN   Name=B3GALNT2;
DR   GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IMP:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
//
ID   B3GLT_HUMAN             Reviewed;         498 AA.
AC   Q6Y288; A8K5F8; Q5W0H2; Q6NUI3;
DE   RecName: Full=Beta-1,3-glucosyltransferase;
DE            Short=Beta3Glc-T;
DE            EC=2.4.1.-;
DE   AltName: Full=Beta-3-glycosyltransferase-like;
GN   Name=B3GALTL; Synonyms=B3GTL;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   B3GN1_HUMAN             Reviewed;         415 AA.
AC   O43505; Q4TTN0;
DE   RecName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase;
DE            EC=2.4.1.149;
DE   AltName: Full=I-beta-1,3-N-acetylglucosaminyltransferase;
DE            Short=iGnT;
DE   AltName: Full=Poly-N-acetyllactosamine extension enzyme;
DE   AltName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1;
GN   Name=B3GNT1; Synonyms=B3GNT6;
DR   GO; GO:0008532; F:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030311; P:poly-N-acetyllactosamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GN2_HUMAN             Reviewed;         397 AA.
AC   Q9NY97; Q54AC1; Q9NQQ9; Q9NQR0; Q9NUT9;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2;
DE            Short=BGnT-2;
DE            Short=Beta-1,3-Gn-T2;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 2;
DE            Short=Beta3Gn-T2;
DE            EC=2.4.1.-;
DE   AltName: Full=Beta-1,3-N-acetylglucosaminyltransferase 1;
DE            Short=BGnT-1;
DE            Short=Beta-1,3-Gn-T1;
DE            Short=Beta3Gn-T1;
DE   AltName: Full=Beta-1,3-galactosyltransferase 7;
DE            Short=Beta-1,3-GalTase 7;
DE            Short=Beta3Gal-T7;
DE            Short=Beta3GalT7;
DE            Short=b3Gal-T7;
DE   AltName: Full=Beta-3-Gx-T7;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7;
GN   Name=B3GNT2; Synonyms=B3GALT7, B3GNT1;
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GN3_HUMAN             Reviewed;         372 AA.
AC   Q9Y2A9; B2RAS4; Q6NWU9; Q6NXU9; Q8WWR6; Q9C0J2;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3;
DE            Short=BGnT-3;
DE            Short=Beta-1,3-Gn-T3;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 3;
DE            Short=Beta3Gn-T3;
DE            EC=2.4.1.146;
DE   AltName: Full=Beta-1,3-galactosyltransferase 8;
DE            Short=Beta-1,3-GalTase 8;
DE            Short=Beta3Gal-T8;
DE            Short=Beta3GalT8;
DE            Short=b3Gal-T8;
DE   AltName: Full=Beta-3-Gx-T8;
DE   AltName: Full=Core 1 extending beta-1,3-N-acetylglucosaminyltransferase;
DE   AltName: Full=Core1-beta3GlcNAcT;
DE   AltName: Full=Transmembrane protein 3;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8;
GN   Name=B3GNT3; Synonyms=B3GALT8, TMEM3; ORFNames=UNQ637/PRO1266;
DR   GO; GO:0047223; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GN4_HUMAN             Reviewed;         378 AA.
AC   Q9C0J1; Q8N5W4; Q8N934; Q8ND21; Q8WWR5; Q8WY02; Q96QH5;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4;
DE            Short=BGnT-4;
DE            Short=Beta-1,3-Gn-T4;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 4;
DE            Short=Beta3Gn-T4;
DE            EC=2.4.1.-;
GN   Name=B3GNT4; ORFNames=UNQ1898/PRO4344;
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GN5_HUMAN             Reviewed;         378 AA.
AC   Q9BYG0; D3DNS5; Q59FE3; Q7L9Z5; Q8WWP9;
DE   RecName: Full=Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase;
DE            EC=2.4.1.206;
DE   AltName: Full=Lactotriaosylceramide synthase;
DE            Short=Lc(3)Cer synthase;
DE            Short=Lc3 synthase;
DE   AltName: Full=UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5;
DE            Short=BGnT-5;
DE            Short=Beta-1,3-Gn-T5;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 5;
DE            Short=Beta3Gn-T5;
GN   Name=B3GNT5;
DR   GO; GO:0008457; F:beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0047256; F:lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008917; F:lipopolysaccharide N-acetylglucosaminyltransferase activity; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; IDA:UniProtKB.
DR   GO; GO:0009247; P:glycolipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   B3GN6_HUMAN             Reviewed;         384 AA.
AC   Q6ZMB0; E9PKS1; Q6ZSC5; Q8TAZ4; Q8TDX1;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6;
DE            Short=BGnT-6;
DE            Short=Beta-1,3-Gn-T6;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 6;
DE            Short=Beta3Gn-T6;
DE            EC=2.4.1.-;
DE   AltName: Full=Core 3 synthase;
GN   Name=B3GNT6;
DR   GO; GO:0047223; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0008378; F:galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0016269; P:O-glycan processing, core 3; NAS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   B3GN7_HUMAN             Reviewed;         401 AA.
AC   Q8NFL0; B3KWY4; B7WNP0;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7;
DE            Short=BGnT-7;
DE            Short=Beta-1,3-Gn-T7;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 7;
DE            Short=Beta3Gn-T7;
DE            EC=2.4.1.-;
GN   Name=B3GNT7;
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B3GN8_HUMAN             Reviewed;         397 AA.
AC   Q7Z7M8;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8;
DE            Short=BGnT-8;
DE            Short=Beta-1,3-Gn-T8;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 8;
DE            Short=Beta3Gn-T8;
DE            EC=2.4.1.-;
GN   Name=B3GNT8; Synonyms=B3GALT7, BGALT15;
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0016262; F:protein N-acetylglucosaminyltransferase activity; IDA:HGNC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0030311; P:poly-N-acetyllactosamine biosynthetic process; IDA:HGNC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   B3GNL_HUMAN             Reviewed;         361 AA.
AC   Q67FW5; Q6GV30; Q8WUT3;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1;
DE            Short=BGnT-like protein 1;
DE            Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1;
DE            Short=Beta3Gn-T-like protein 1;
DE            Short=Beta3GnTL1;
DE            EC=2.4.1.-;
DE   AltName: Full=Beta-1,3-N-acetylglucosaminyltransferase 8;
DE            Short=BGnT-8;
DE            Short=Beta-1,3-Gn-T8;
DE            Short=Beta3Gn-T8;
GN   Name=B3GNTL1; Synonyms=B3GNT8;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   B3GN9_HUMAN             Reviewed;         402 AA.
AC   Q6UX72; Q96EK0;
DE   RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9;
DE            Short=BGnT-9;
DE            Short=Beta-1,3-Gn-T9;
DE            Short=Beta-1,3-N-acetylglucosaminyltransferase 9;
DE            Short=Beta3Gn-T9;
DE            EC=2.4.1.-;
GN   Name=B3GNT9; ORFNames=UNQ1922/PRO4397;
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
//
ID   B3GT1_HUMAN             Reviewed;         326 AA.
AC   Q9Y5Z6; D3DPB8; Q53SS2;
DE   RecName: Full=Beta-1,3-galactosyltransferase 1;
DE            Short=Beta-1,3-GalTase 1;
DE            Short=Beta3Gal-T1;
DE            Short=Beta3GalT1;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1;
GN   Name=B3GALT1;
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; IDA:UniProtKB.
//
ID   B3GT2_HUMAN             Reviewed;         422 AA.
AC   O43825; B2RAB1; Q9BZQ9;
DE   RecName: Full=Beta-1,3-galactosyltransferase 2;
DE            Short=Beta-1,3-GalTase 2;
DE            Short=Beta3Gal-T2;
DE            Short=Beta3GalT2;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2;
GN   Name=B3GALT2;
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   B3GT5_HUMAN             Reviewed;         310 AA.
AC   Q9Y2C3; A8KA86; D3DSI3; Q2M3L5; Q53Z19; Q9NY96; Q9P1X6; Q9P1X7;
DE   RecName: Full=Beta-1,3-galactosyltransferase 5;
DE            Short=Beta-1,3-GalTase 5;
DE            Short=Beta3Gal-T5;
DE            Short=Beta3GalT5;
DE            Short=b3Gal-T5;
DE            EC=2.4.1.-;
DE   AltName: Full=Beta-3-Gx-T5;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5;
GN   Name=B3GALT5;
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   B3GT4_HUMAN             Reviewed;         378 AA.
AC   O96024;
DE   RecName: Full=Beta-1,3-galactosyltransferase 4;
DE            Short=Beta-1,3-GalTase 4;
DE            Short=Beta3Gal-T4;
DE            Short=Beta3GalT4;
DE            Short=GalT4;
DE            Short=b3Gal-T4;
DE            EC=2.4.1.62;
DE   AltName: Full=Gal-T2;
DE   AltName: Full=Ganglioside galactosyltransferase;
DE   AltName: Full=UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase;
GN   Name=B3GALT4; Synonyms=GALT4;
DR   GO; GO:0047915; F:ganglioside galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   B3GT6_HUMAN             Reviewed;         329 AA.
AC   Q96L58; Q5T7M5;
DE   RecName: Full=Beta-1,3-galactosyltransferase 6;
DE            Short=Beta-1,3-GalTase 6;
DE            Short=Beta3Gal-T6;
DE            Short=Beta3GalT6;
DE            EC=2.4.1.134;
DE   AltName: Full=GAG GalTII;
DE   AltName: Full=Galactosyltransferase II;
DE   AltName: Full=Galactosylxylosylprotein 3-beta-galactosyltransferase;
DE   AltName: Full=UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6;
GN   Name=B3GALT6;
DR   GO; GO:0047220; F:galactosylxylosylprotein 3-beta-galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008499; F:UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0035250; F:UDP-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GN1_HUMAN             Reviewed;         533 AA.
AC   Q00973;
DE   RecName: Full=Beta-1,4 N-acetylgalactosaminyltransferase 1;
DE            EC=2.4.1.92;
DE   AltName: Full=(N-acetylneuraminyl)-galactosylglucosylceramide;
DE   AltName: Full=GM2/GD2 synthase;
DE   AltName: Full=GalNAc-T;
GN   Name=B4GALNT1; Synonyms=GALGT, SIAT2;
DR   GO; GO:0003947; F:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:ProtInc.
DR   GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   B4GN2_HUMAN             Reviewed;         566 AA.
AC   Q8NHY0; B4DZE4; Q14CP1; Q86Y40;
DE   RecName: Full=Beta-1,4 N-acetylgalactosaminyltransferase 2;
DE            EC=2.4.1.-;
DE   AltName: Full=Sd(a) beta-1,4-GalNAc transferase;
DE   AltName: Full=UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase;
GN   Name=B4GALNT2; Synonyms=GALGT2;
DR   GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0030259; P:lipid glycosylation; IEA:InterPro.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019276; P:UDP-N-acetylgalactosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; IEA:Ensembl.
//
ID   B4GN3_HUMAN             Reviewed;         998 AA.
AC   Q6L9W6; Q6ZNC1; Q8N7T6;
DE   RecName: Full=Beta-1,4-N-acetylgalactosaminyltransferase 3;
DE            Short=B4GalNAcT3;
DE            Short=Beta4GalNAc-T3;
DE            Short=Beta4GalNAcT3;
DE            EC=2.4.1.244;
DE   AltName: Full=Beta-1,4-N-acetylgalactosaminyltransferase III;
DE   AltName: Full=N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2;
DE            Short=NGalNAc-T2;
GN   Name=B4GALNT3;
DR   GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IDA:HGNC.
DR   GO; GO:0033842; F:N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
//
ID   B4GN4_HUMAN             Reviewed;        1039 AA.
AC   Q76KP1; Q96LV2;
DE   RecName: Full=N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1;
DE            Short=NGalNAc-T1;
DE            EC=2.4.1.244;
DE   AltName: Full=Beta-1,4-N-acetylgalactosaminyltransferase IV;
DE            Short=Beta4GalNAc-T4;
DE            Short=Beta4GalNAcT4;
GN   Name=B4GALNT4;
DR   GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IDA:HGNC.
DR   GO; GO:0033842; F:N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
//
ID   B4GT1_HUMAN             Reviewed;         398 AA.
AC   P15291; B2R710; D3DRL2; Q12909; Q12910; Q12911; Q14456; Q14509;
AC   Q14523;
DE   RecName: Full=Beta-1,4-galactosyltransferase 1;
DE            Short=Beta-1,4-GalTase 1;
DE            Short=Beta4Gal-T1;
DE            Short=b4Gal-T1;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1;
DE   Includes:
DE     RecName: Full=Lactose synthase A protein;
DE              EC=2.4.1.22;
DE   Includes:
DE     RecName: Full=N-acetyllactosamine synthase;
DE              EC=2.4.1.90;
DE     AltName: Full=Nal synthase;
DE   Includes:
DE     RecName: Full=Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase;
DE              EC=2.4.1.38;
DE   Includes:
DE     RecName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase;
DE              EC=2.4.1.-;
DE   Contains:
DE     RecName: Full=Processed beta-1,4-galactosyltransferase 1;
GN   Name=B4GALT1; Synonyms=GGTB2;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0048487; F:beta-tubulin binding; IPI:UniProtKB.
DR   GO; GO:0008378; F:galactosyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0004461; F:lactose synthase activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0003945; F:N-acetyllactosamine synthase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0035250; F:UDP-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0060055; P:angiogenesis involved in wound healing; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0045136; P:development of secondary sexual characteristics; IEA:Ensembl.
DR   GO; GO:0002064; P:epithelial cell development; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0005989; P:lactose biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007341; P:penetration of zona pellucida; IEA:Ensembl.
DR   GO; GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IEA:Ensembl.
DR   GO; GO:0060054; P:positive regulation of epithelial cell proliferation involved in wound healing; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0060046; P:regulation of acrosome reaction; IEA:Ensembl.
DR   GO; GO:0051270; P:regulation of cellular component movement; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GT2_HUMAN             Reviewed;         372 AA.
AC   O60909; B3KTP0; B4DE14; D3DPY6; D3DPY7; O60511; Q4V9L9; Q5T4X5;
AC   Q5T4Y5; Q9BUP6; Q9NSY7;
DE   RecName: Full=Beta-1,4-galactosyltransferase 2;
DE            Short=Beta-1,4-GalTase 2;
DE            Short=Beta4Gal-T2;
DE            Short=b4Gal-T2;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2;
DE   Includes:
DE     RecName: Full=Lactose synthase A protein;
DE              EC=2.4.1.22;
DE   Includes:
DE     RecName: Full=N-acetyllactosamine synthase;
DE              EC=2.4.1.90;
DE     AltName: Full=Nal synthase;
DE   Includes:
DE     RecName: Full=Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase;
DE              EC=2.4.1.38;
DE   Includes:
DE     RecName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase;
DE              EC=2.4.1.-;
GN   Name=B4GALT2;
DR   GO; GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008378; F:galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0004461; F:lactose synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003945; F:N-acetyllactosamine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GT3_HUMAN             Reviewed;         393 AA.
AC   O60512; D3DVG3; O60910; Q9BPZ4; Q9H8T2;
DE   RecName: Full=Beta-1,4-galactosyltransferase 3;
DE            Short=Beta-1,4-GalTase 3;
DE            Short=Beta4Gal-T3;
DE            Short=b4Gal-T3;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3;
DE   Includes:
DE     RecName: Full=N-acetyllactosamine synthase;
DE              EC=2.4.1.90;
DE     AltName: Full=Nal synthase;
DE   Includes:
DE     RecName: Full=Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase;
DE              EC=2.4.1.38;
DE   Includes:
DE     RecName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase;
DE              EC=2.4.1.-;
GN   Name=B4GALT3;
DR   GO; GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008378; F:galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003945; F:N-acetyllactosamine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GT4_HUMAN             Reviewed;         344 AA.
AC   O60513; Q68D68; Q9BSW3; Q9C078;
DE   RecName: Full=Beta-1,4-galactosyltransferase 4;
DE            Short=Beta-1,4-GalTase 4;
DE            Short=Beta4Gal-T4;
DE            Short=b4Gal-T4;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4;
DE   Includes:
DE     RecName: Full=N-acetyllactosamine synthase;
DE              EC=2.4.1.90;
DE     AltName: Full=Nal synthase;
DE   Includes:
DE     RecName: Full=Lactotriaosylceramide beta-1,4-galactosyltransferase;
DE              EC=2.4.1.275;
DE     AltName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase;
GN   Name=B4GALT4; ORFNames=UNQ552/PRO1109;
DR   GO; GO:0008378; F:galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003945; F:N-acetyllactosamine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006643; P:membrane lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GT6_HUMAN             Reviewed;         382 AA.
AC   Q9UBX8; O60514;
DE   RecName: Full=Beta-1,4-galactosyltransferase 6;
DE            Short=Beta-1,4-GalTase 6;
DE            Short=Beta4Gal-T6;
DE            Short=b4Gal-T6;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6;
DE   Includes:
DE     RecName: Full=Glucosylceramide beta-1,4-galactosyltransferase;
DE              EC=2.4.1.274;
DE     AltName: Full=Lactosylceramide synthase;
DE              Short=LacCer synthase;
DE     AltName: Full=UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase;
GN   Name=B4GALT6;
DR   GO; GO:0008378; F:galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GT5_HUMAN             Reviewed;         388 AA.
AC   O43286; E1P625; Q2M394; Q9UJQ8;
DE   RecName: Full=Beta-1,4-galactosyltransferase 5;
DE            Short=Beta-1,4-GalTase 5;
DE            Short=Beta4Gal-T5;
DE            Short=b4Gal-T5;
DE            EC=2.4.1.-;
DE   AltName: Full=Beta-1,4-GalT II;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5;
GN   Name=B4GALT5;
DR   GO; GO:0008378; F:galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B4GT7_HUMAN             Reviewed;         327 AA.
AC   Q9UBV7; B3KN39; Q9UHN2;
DE   RecName: Full=Beta-1,4-galactosyltransferase 7;
DE            Short=Beta-1,4-GalTase 7;
DE            Short=Beta4Gal-T7;
DE            Short=b4Gal-T7;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7;
DE   AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7;
DE   Includes:
DE     RecName: Full=Xylosylprotein 4-beta-galactosyltransferase;
DE              EC=2.4.1.133;
DE     AltName: Full=Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I;
DE     AltName: Full=UDP-galactose:beta-xylose beta-1,4-galactosyltransferase;
DE     AltName: Full=XGPT;
DE     AltName: Full=XGalT-1;
DE     AltName: Full=Xylosylprotein beta-1,4-galactosyltransferase;
GN   Name=B4GALT7; Synonyms=XGALT1; ORFNames=UNQ748/PRO1478;
DR   GO; GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008378; F:galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0046525; F:xylosylprotein 4-beta-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0043206; P:extracellular fibril organization; IMP:UniProtKB.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IMP:UniProtKB.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   B9D1_HUMAN              Reviewed;         204 AA.
AC   Q9UPM9; Q9BU22;
DE   RecName: Full=B9 domain-containing protein 1;
DE   AltName: Full=MKS1-related protein 1;
GN   Name=B9D1; Synonyms=MKSR1;
DR   GO; GO:0008158; F:hedgehog receptor activity; ISS:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0035051; P:cardiocyte differentiation; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060563; P:neuroepithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   B9D2_HUMAN              Reviewed;         175 AA.
AC   Q9BPU9;
DE   RecName: Full=B9 domain-containing protein 2;
DE   AltName: Full=MKS1-related protein 2;
GN   Name=B9D2; Synonyms=MKSR2;
DR   GO; GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   BAALC_HUMAN             Reviewed;         180 AA.
AC   Q8WXS3; Q8WTP6; Q8WXS0; Q8WXS1; Q8WXS2; Q9HA93;
DE   RecName: Full=Brain and acute leukemia cytoplasmic protein;
GN   Name=BAALC;
//
ID   BAAOS_HUMAN             Reviewed;         105 AA.
AC   P0C853;
DE   RecName: Full=Putative BAALC opposite strand protein;
GN   Name=BAALCOS; Synonyms=C8orf56;
//
ID   BAAT_HUMAN              Reviewed;         418 AA.
AC   Q14032; Q3B7W9; Q96L31;
DE   RecName: Full=Bile acid-CoA:amino acid N-acyltransferase;
DE            Short=BACAT;
DE            Short=BAT;
DE            EC=2.3.1.65;
DE   AltName: Full=Glycine N-choloyltransferase;
DE   AltName: Full=Long-chain fatty-acyl-CoA hydrolase;
DE            EC=3.1.2.2;
GN   Name=BAAT;
DR   GO; GO:0047963; F:glycine N-choloyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0052816; F:long-chain acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0052815; F:medium-chain acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0016410; F:N-acyltransferase activity; IDA:MGI.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0052817; F:very long chain acyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0002152; P:bile acid conjugation; IDA:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006544; P:glycine metabolic process; IDA:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019530; P:taurine metabolic process; IDA:UniProtKB.
//
ID   BABA1_HUMAN             Reviewed;         329 AA.
AC   Q9NWV8; A8MQT0; B4DRY9; B4DVR1; Q6FIA0; Q9P018;
DE   RecName: Full=BRISC and BRCA1-A complex member 1;
DE   AltName: Full=Mediator of RAP80 interactions and targeting subunit of 40 kDa;
DE   AltName: Full=New component of the BRCA1-A complex;
GN   Name=BABAM1; Synonyms=C19orf62, MERIT40, NBA1; ORFNames=HSPC142;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
//
ID   BACD1_HUMAN             Reviewed;         329 AA.
AC   Q8WZ19; A8K0R5; Q96P93; Q96SA1;
DE   RecName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1;
DE            Short=hBACURD1;
DE   AltName: Full=BTB/POZ domain-containing protein KCTD13;
DE   AltName: Full=Polymerase delta-interacting protein 1;
DE   AltName: Full=TNFAIP1-like protein;
GN   Name=KCTD13; Synonyms=BACURD1, PDIP1, POLDIP1;
GN   ORFNames=FKSG86, PP6832;
DR   GO; GO:0017049; F:GTP-Rho binding; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; ISS:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0043149; P:stress fiber assembly; IMP:UniProtKB.
//
ID   BACD2_HUMAN             Reviewed;         316 AA.
AC   Q13829; Q5TZQ1;
DE   RecName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2;
DE            Short=hBACURD2;
DE   AltName: Full=BTB/POZ domain-containing protein TNFAIP1;
DE   AltName: Full=Protein B12;
DE   AltName: Full=Tumor necrosis factor, alpha-induced protein 1, endothelial;
GN   Name=TNFAIP1; Synonyms=BACURD2, EDP1;
DR   GO; GO:0017049; F:GTP-Rho binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEP:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0043149; P:stress fiber assembly; IMP:UniProtKB.
//
ID   BACD3_HUMAN             Reviewed;         313 AA.
AC   Q9H3F6; Q53HN2; Q59FV1; Q6PL47; Q96SU0;
DE   RecName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3;
DE            Short=hBACURD3;
DE   AltName: Full=BTB/POZ domain-containing protein KCTD10;
DE   AltName: Full=Potassium channel tetramerization domain-containing protein 10;
GN   Name=KCTD10; Synonyms=ULR061; ORFNames=MSTP028;
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   BACE1_HUMAN             Reviewed;         501 AA.
AC   P56817; A0M8W7; B0YIU9; E9PE65; H7BXJ9; Q9BYB9; Q9BYC0; Q9BYC1;
AC   Q9UJT5; Q9ULS1;
DE   RecName: Full=Beta-secretase 1;
DE            EC=3.4.23.46;
DE   AltName: Full=Aspartyl protease 2;
DE            Short=ASP2;
DE            Short=Asp 2;
DE   AltName: Full=Beta-site amyloid precursor protein cleaving enzyme 1;
DE            Short=Beta-site APP cleaving enzyme 1;
DE   AltName: Full=Memapsin-2;
DE   AltName: Full=Membrane-associated aspartic protease 2;
DE   Flags: Precursor;
GN   Name=BACE1; Synonyms=BACE, KIAA1149;
DR   GuidetoPHARMACOLOGY; 2330; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:Alzheimers_University_of_Toronto.
DR   GO; GO:0008798; F:beta-aspartyl-peptidase activity; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; TAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   BACE2_HUMAN             Reviewed;         518 AA.
AC   Q9Y5Z0; A8K7P1; Q5DIH8; Q8N2D4; Q9H2V8; Q9NZL1; Q9NZL2; Q9UJT6;
DE   RecName: Full=Beta-secretase 2;
DE            EC=3.4.23.45;
DE   AltName: Full=Aspartic-like protease 56 kDa;
DE   AltName: Full=Aspartyl protease 1;
DE            Short=ASP1;
DE            Short=Asp 1;
DE   AltName: Full=Beta-site amyloid precursor protein cleaving enzyme 2;
DE            Short=Beta-site APP cleaving enzyme 2;
DE   AltName: Full=Down region aspartic protease;
DE            Short=DRAP;
DE   AltName: Full=Memapsin-1;
DE   AltName: Full=Membrane-associated aspartic protease 1;
DE   AltName: Full=Theta-secretase;
DE   Flags: Precursor;
GN   Name=BACE2; Synonyms=AEPLC, ALP56, ASP21;
GN   ORFNames=CDA13, UNQ418/PRO852;
DR   GuidetoPHARMACOLOGY; 2331; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0016486; P:peptide hormone processing; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   BACH2_HUMAN             Reviewed;         841 AA.
AC   Q9BYV9; E1P518; Q59H70; Q5T793; Q9NTS5;
DE   RecName: Full=Transcription regulator protein BACH2;
DE   AltName: Full=BTB and CNC homolog 2;
GN   Name=BACH2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BACH1_HUMAN             Reviewed;         736 AA.
AC   O14867; O43285;
DE   RecName: Full=Transcription regulator protein BACH1;
DE   AltName: Full=BTB and CNC homolog 1;
DE   AltName: Full=HA2303;
GN   Name=BACH1;
DR   GO; GO:0020037; F:heme binding; NAS:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0000117; P:regulation of transcription involved in G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
//
ID   BACHL_HUMAN             Reviewed;         252 AA.
AC   Q6ZUV0;
DE   RecName: Full=Cytosolic acyl coenzyme A thioester hydrolase-like;
DE            EC=3.1.2.2;
DE   AltName: Full=Acyl-CoA thioesterase 7-like;
GN   Name=ACOT7L; Synonyms=BACHL;
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IEA:UniProtKB-EC.
//
ID   BACH_HUMAN              Reviewed;         380 AA.
AC   O00154; A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; O43703; Q53Y78;
AC   Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539;
AC   Q9Y540;
DE   RecName: Full=Cytosolic acyl coenzyme A thioester hydrolase;
DE            EC=3.1.2.2;
DE   AltName: Full=Acyl-CoA thioesterase 7;
DE   AltName: Full=Brain acyl-CoA hydrolase;
DE            Short=BACH;
DE   AltName: Full=CTE-IIa;
DE            Short=CTE-II;
DE   AltName: Full=Long chain acyl-CoA thioester hydrolase;
GN   Name=ACOT7; Synonyms=BACH;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IDA:BHF-UCL.
DR   GO; GO:0036042; F:long-chain fatty acyl-CoA binding; IDA:BHF-UCL.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0009062; P:fatty acid catabolic process; IEA:Ensembl.
DR   GO; GO:0036116; P:long-chain fatty-acyl-CoA catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051792; P:medium-chain fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0036114; P:medium-chain fatty-acyl-CoA catabolic process; IDA:BHF-UCL.
DR   GO; GO:1900535; P:palmitic acid biosynthetic process; IDA:BHF-UCL.
//
ID   BAD_HUMAN               Reviewed;         168 AA.
AC   Q92934; O14803; Q6FH21;
DE   RecName: Full=Bcl2 antagonist of cell death;
DE            Short=BAD;
DE   AltName: Full=Bcl-2-binding component 6;
DE   AltName: Full=Bcl-2-like protein 8;
DE            Short=Bcl2-L-8;
DE   AltName: Full=Bcl-XL/Bcl-2-associated death promoter;
GN   Name=BAD; Synonyms=BBC6, BCL2L8;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0046031; P:ADP metabolic process; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0046034; P:ATP metabolic process; ISS:UniProtKB.
DR   GO; GO:0060154; P:cellular process regulating host cell cycle in response to virus; IEA:Ensembl.
DR   GO; GO:0071247; P:cellular response to chromate; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0071396; P:cellular response to lipid; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0071316; P:cellular response to nicotine; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006007; P:glucose catabolic process; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0046931; P:pore complex assembly; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060139; P:positive regulation of apoptotic process by virus; IEA:Ensembl.
DR   GO; GO:0010508; P:positive regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0033133; P:positive regulation of glucokinase activity; ISS:UniProtKB.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0010918; P:positive regulation of mitochondrial membrane potential; ISS:UniProtKB.
DR   GO; GO:1901216; P:positive regulation of neuron death; IEA:Ensembl.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:2000078; P:positive regulation of type B pancreatic cell development; ISS:UniProtKB.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IMP:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0034201; P:response to oleic acid; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0019050; P:suppression by virus of host apoptotic process; IEA:Ensembl.
DR   GO; GO:0044342; P:type B pancreatic cell proliferation; ISS:UniProtKB.
//
ID   BAFL_HUMAN              Reviewed;          90 AA.
AC   Q9H503; D3DW25; F5H3F6; Q7Z4M6;
DE   RecName: Full=Barrier-to-autointegration factor-like protein;
DE            Short=BAF-L;
DE   AltName: Full=Barrier-to-autointegration factor 2;
GN   Name=BANF2; Synonyms=BAFL, C20orf179;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
//
ID   BAF_HUMAN               Reviewed;          89 AA.
AC   O75531; O60558; Q6FGG7;
DE   RecName: Full=Barrier-to-autointegration factor;
DE   AltName: Full=Breakpoint cluster region protein 1;
DE   Contains:
DE     RecName: Full=Barrier-to-autointegration factor, N-terminally processed;
GN   Name=BANF1; Synonyms=BAF, BCRG1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015074; P:DNA integration; IEA:Ensembl.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   BAG1_HUMAN              Reviewed;         345 AA.
AC   Q99933; O75315; Q14414; Q53H32; Q5VZE8; Q5VZE9; Q5VZF0; Q96TG2;
AC   Q9Y2V4;
DE   RecName: Full=BAG family molecular chaperone regulator 1;
DE            Short=BAG-1;
DE   AltName: Full=Bcl-2-associated athanogene 1;
GN   Name=BAG1; Synonyms=HAP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0070389; P:chaperone cofactor-dependent protein refolding; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
//
ID   BAG2_HUMAN              Reviewed;         211 AA.
AC   O95816; Q08AS9; Q6FID0;
DE   RecName: Full=BAG family molecular chaperone regulator 2;
DE            Short=BAG-2;
DE   AltName: Full=Bcl-2-associated athanogene 2;
GN   Name=BAG2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0019538; P:protein metabolic process; IDA:MGI.
//
ID   BAG3_HUMAN              Reviewed;         575 AA.
AC   O95817; A8K5L8; Q3B763; Q9NT20; Q9P120;
DE   RecName: Full=BAG family molecular chaperone regulator 3;
DE            Short=BAG-3;
DE   AltName: Full=Bcl-2-associated athanogene 3;
DE   AltName: Full=Bcl-2-binding protein Bis;
DE   AltName: Full=Docking protein CAIR-1;
GN   Name=BAG3; Synonyms=BIS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:MGI.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0010664; P:negative regulation of striated muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
//
ID   BAG4_HUMAN              Reviewed;         457 AA.
AC   O95429; B4E217; O95818;
DE   RecName: Full=BAG family molecular chaperone regulator 4;
DE            Short=BAG-4;
DE   AltName: Full=Bcl-2-associated athanogene 4;
DE   AltName: Full=Silencer of death domains;
GN   Name=BAG4; Synonyms=SODD;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0090367; P:negative regulation of mRNA modification; IEA:Ensembl.
DR   GO; GO:2001145; P:negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0097178; P:ruffle assembly; IEA:Ensembl.
//
ID   BAG5_HUMAN              Reviewed;         447 AA.
AC   Q9UL15; O94950; Q86W59;
DE   RecName: Full=BAG family molecular chaperone regulator 5;
DE            Short=BAG-5;
DE   AltName: Full=Bcl-2-associated athanogene 5;
GN   Name=BAG5; Synonyms=KIAA0873;
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.
DR   GO; GO:0061084; P:negative regulation of protein refolding; ISS:BHF-UCL.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; ISS:BHF-UCL.
DR   GO; GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; ISS:BHF-UCL.
DR   GO; GO:0070997; P:neuron death; ISS:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0090083; P:regulation of inclusion body assembly; IMP:BHF-UCL.
//
ID   BAG6_HUMAN              Reviewed;        1132 AA.
AC   P46379; A2ADJ7; A3KQ42; A3KQ44; A6NGY6; A6PWF7; B0UX84; B4DZ12;
AC   B4E3V4; E7EMZ4; F8VXY4; O95874; Q5HYL9; Q5SQ35; Q5SQ36; Q5SQ37;
AC   Q5SQ41; Q5SRP8; Q5SRP9; Q5STC1; Q5STX1; Q5STX3; Q96SA6; Q9BCN4;
DE   RecName: Full=Large proline-rich protein BAG6;
DE   AltName: Full=BAG family molecular chaperone regulator 6;
DE   AltName: Full=BCL2-associated athanogene 6;
DE            Short=BAG-6;
DE            Short=BAG6;
DE   AltName: Full=HLA-B-associated transcript 3;
DE   AltName: Full=Protein G3;
DE   AltName: Full=Protein Scythe;
GN   Name=BAG6; Synonyms=BAT3, G3;
DR   GO; GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.
DR   GO; GO:0070628; F:proteasome binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0018393; P:internal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0030324; P:lung development; ISS:UniProtKB.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; ISS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
DR   GO; GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IDA:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   BAGE1_HUMAN             Reviewed;          43 AA.
AC   Q13072; A4IF47;
DE   RecName: Full=B melanoma antigen 1;
DE            Short=B melanoma antigen;
DE   AltName: Full=Antigen MZ2-BA;
DE   AltName: Full=Cancer/testis antigen 2.1;
DE            Short=CT2.1;
DE   Flags: Precursor;
GN   Name=BAGE; Synonyms=BAGE1;
//
ID   BAGE2_HUMAN             Reviewed;         109 AA.
AC   Q86Y30; A8K925; Q08ER0;
DE   RecName: Full=B melanoma antigen 2;
DE   AltName: Full=Cancer/testis antigen 2.2;
DE            Short=CT2.2;
DE   Flags: Precursor;
GN   Name=BAGE2;
//
ID   BAGE5_HUMAN             Reviewed;          43 AA.
AC   Q86Y27;
DE   RecName: Full=B melanoma antigen 5;
DE   AltName: Full=Cancer/testis antigen 2.5;
DE            Short=CT2.5;
DE   Flags: Precursor;
GN   Name=BAGE5;
//
ID   BAGE4_HUMAN             Reviewed;          39 AA.
AC   Q86Y28;
DE   RecName: Full=B melanoma antigen 4;
DE   AltName: Full=Cancer/testis antigen 2.4;
DE            Short=CT2.4;
DE   Flags: Precursor;
GN   Name=BAGE4; Synonyms=MLL3P;
//
ID   BAGE3_HUMAN             Reviewed;         109 AA.
AC   Q86Y29;
DE   RecName: Full=B melanoma antigen 3;
DE   AltName: Full=Cancer/testis antigen 2.3;
DE            Short=CT2.3;
DE   Flags: Precursor;
GN   Name=BAGE3;
//
ID   BAHC1_HUMAN             Reviewed;        2608 AA.
AC   Q9P281; Q5U629;
DE   RecName: Full=BAH and coiled-coil domain-containing protein 1;
DE   AltName: Full=Bromo adjacent homology domain-containing protein 2;
DE            Short=BAH domain-containing protein 2;
GN   Name=BAHCC1; Synonyms=BAHD2, KIAA1447;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
//
ID   BAHD1_HUMAN             Reviewed;         780 AA.
AC   Q8TBE0; Q8NDF7; Q9Y2F4;
DE   RecName: Full=Bromo adjacent homology domain-containing 1 protein;
DE            Short=BAH domain-containing protein 1;
GN   Name=BAHD1; Synonyms=KIAA0945;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031507; P:heterochromatin assembly; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BAI1_HUMAN              Reviewed;        1584 AA.
AC   O14514;
DE   RecName: Full=Brain-specific angiogenesis inhibitor 1;
DE   Flags: Precursor;
GN   Name=BAI1;
DR   GuidetoPHARMACOLOGY; 174; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007409; P:axonogenesis; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   BAI2_HUMAN              Reviewed;        1585 AA.
AC   O60241; B9EGK9; Q5T6K0; Q8NGW8; Q96GZ9;
DE   RecName: Full=Brain-specific angiogenesis inhibitor 2;
DE   Flags: Precursor;
GN   Name=BAI2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
//
ID   BAI3_HUMAN              Reviewed;        1522 AA.
AC   O60242; O60297; Q2NKN6; Q5VY37; Q9BX54;
DE   RecName: Full=Brain-specific angiogenesis inhibitor 3;
DE   Flags: Precursor;
GN   Name=BAI3; Synonyms=KIAA0550;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   BAIP2_HUMAN             Reviewed;         552 AA.
AC   Q9UQB8; O43858; Q53HB1; Q86WC1; Q8N5C0; Q96CR7; Q9UBR3; Q9UQ43;
DE   RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2;
DE            Short=BAI-associated protein 2;
DE            Short=BAI1-associated protein 2;
DE            Short=Protein BAP2;
DE   AltName: Full=Fas ligand-associated factor 3;
DE            Short=FLAF3;
DE   AltName: Full=Insulin receptor substrate p53/p58;
DE            Short=IRS-58;
DE            Short=IRSp53/58;
DE   AltName: Full=Insulin receptor substrate protein of 53 kDa;
DE            Short=IRSp53;
DE            Short=Insulin receptor substrate p53;
GN   Name=BAIAP2;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0070064; F:proline-rich region binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0051764; P:actin crosslink formation; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; TAS:ProtInc.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0046847; P:filopodium assembly; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0009617; P:response to bacterium; IMP:UniProtKB.
//
ID   BAIP3_HUMAN             Reviewed;        1187 AA.
AC   O94812; A2A2B2; B2RCD7; B4DGS5; B4DIK3; B4DRK9; B4DRP1; E7EUB9;
AC   H3BUH8; H3BVI3; H7C2Q1; O94839; Q2M226; Q658J2; Q76N05; Q96RZ3;
AC   Q9UJK1;
DE   RecName: Full=BAI1-associated protein 3;
DE            Short=BAP3;
GN   Name=BAIAP3; Synonyms=KIAA0734;
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IPI:MGI.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:ProtInc.
//
ID   BAKOR_HUMAN             Reviewed;         492 AA.
AC   Q6ZNE5; A6NJE4; A8K9U5; B7ZWP5; O94920; Q32MK7; Q32MK8;
DE   RecName: Full=Beclin 1-associated autophagy-related key regulator;
DE            Short=Barkor;
DE   AltName: Full=Autophagy-related protein 14-like protein;
DE            Short=Atg14L;
GN   Name=ATG14; Synonyms=KIAA0831;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; IEA:InterPro.
//
ID   BAK_HUMAN               Reviewed;         211 AA.
AC   Q16611; Q6I9T6; Q92533;
DE   RecName: Full=Bcl-2 homologous antagonist/killer;
DE   AltName: Full=Apoptosis regulator BAK;
DE   AltName: Full=Bcl-2-like protein 7;
DE            Short=Bcl2-L-7;
GN   Name=BAK1; Synonyms=BAK, BCL2L7, CDN1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:1902262; P:apoptotic process involved in patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0001783; P:B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0002352; P:B cell negative selection; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IMP:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0010248; P:establishment or maintenance of transmembrane electrochemical gradient; IDA:HGNC.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0044346; P:fibroblast apoptotic process; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0008053; P:mitochondrial fusion; IEA:Ensembl.
DR   GO; GO:0002262; P:myeloid cell homeostasis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0048597; P:post-embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IDA:BHF-UCL.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IDA:HGNC.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IDA:HGNC.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009620; P:response to fungus; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0010046; P:response to mycotoxin; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0010225; P:response to UV-C; IEA:Ensembl.
DR   GO; GO:0070242; P:thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   BAMBI_HUMAN             Reviewed;         260 AA.
AC   Q13145;
DE   RecName: Full=BMP and activin membrane-bound inhibitor homolog;
DE   AltName: Full=Non-metastatic gene A protein;
DE   AltName: Full=Putative transmembrane protein NMA;
DE   Flags: Precursor;
GN   Name=BAMBI; Synonyms=NMA;
DR   GO; GO:0005109; F:frizzled binding; IPI:BHF-UCL.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; TAS:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   BANK1_HUMAN             Reviewed;         785 AA.
AC   Q8NDB2; A8K7W8; B0F3S2; Q8N5K8; Q8NB56; Q8WYN5; Q9NWP2;
DE   RecName: Full=B-cell scaffold protein with ankyrin repeats;
GN   Name=BANK1;
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
//
ID   BANP_HUMAN              Reviewed;         519 AA.
AC   Q8N9N5; A8MU25; A8MX25; B2RCF7; B4DNJ9; F5GZM0; Q96GJ7; Q9NWY1;
DE   RecName: Full=Protein BANP;
DE   AltName: Full=BEN domain-containing protein 1;
DE   AltName: Full=Btg3-associated nuclear protein;
DE   AltName: Full=Scaffold/matrix-associated region-1-binding protein;
GN   Name=BANP; Synonyms=BEND1, SMAR1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BAP18_HUMAN             Reviewed;         172 AA.
AC   Q8IXM2; B4DIV3; C9J4G0; E9PB29;
DE   RecName: Full=Chromatin complexes subunit BAP18;
DE   AltName: Full=BPTF-associated protein of 18 kDa;
GN   Name=BAP18; Synonyms=C17orf49;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
//
ID   BAP1_HUMAN              Reviewed;         729 AA.
AC   Q92560; A8K993; Q6LEM0; Q7Z5E8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase BAP1;
DE            EC=3.4.19.12;
DE   AltName: Full=BRCA1-associated protein 1;
DE   AltName: Full=Cerebral protein 6;
GN   Name=BAP1; Synonyms=KIAA0272; ORFNames=hucep-6;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0035522; P:monoubiquitinated histone H2A deubiquitination; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   BAP29_HUMAN             Reviewed;         241 AA.
AC   Q9UHQ4; G5E9L4; O95003;
DE   RecName: Full=B-cell receptor-associated protein 29;
DE            Short=BCR-associated protein 29;
DE            Short=Bap29;
GN   Name=BCAP29; Synonyms=BAP29;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   BAP31_HUMAN             Reviewed;         246 AA.
AC   P51572; B3KQ79; D3DWV5; Q13836; Q96CF0;
DE   RecName: Full=B-cell receptor-associated protein 31;
DE            Short=BCR-associated protein 31;
DE            Short=Bap31;
DE   AltName: Full=6C6-AG tumor-associated antigen;
DE   AltName: Full=Protein CDM;
DE   AltName: Full=p28;
GN   Name=BCAP31; Synonyms=BAP31, DXS1357E;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IMP:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   BARD1_HUMAN             Reviewed;         777 AA.
AC   Q99728; O43574; Q53SS5;
DE   RecName: Full=BRCA1-associated RING domain protein 1;
DE            Short=BARD-1;
DE            EC=6.3.2.-;
GN   Name=BARD1;
DR   GO; GO:0019900; F:kinase binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:MGI.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007050; P:cell cycle arrest; NAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; NAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.
DR   GO; GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
DR   GO; GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.
DR   GO; GO:0001894; P:tissue homeostasis; TAS:UniProtKB.
//
ID   BARH1_HUMAN             Reviewed;         327 AA.
AC   Q9BZE3; Q5T6V2; Q9NY88;
DE   RecName: Full=BarH-like 1 homeobox protein;
GN   Name=BARHL1; ORFNames=FKSG31;
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   BARH2_HUMAN             Reviewed;         387 AA.
AC   Q9NY43; A0AVP2; Q7Z4N7;
DE   RecName: Full=BarH-like 2 homeobox protein;
GN   Name=BARHL2;
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001709; P:cell fate determination; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0030516; P:regulation of axon extension; IEA:Ensembl.
//
ID   BARX1_HUMAN             Reviewed;         254 AA.
AC   Q9HBU1; Q6P2R4; Q96GH8;
DE   RecName: Full=Homeobox protein BarH-like 1;
GN   Name=BARX1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0055123; P:digestive system development; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BARX2_HUMAN             Reviewed;         279 AA.
AC   Q9UMQ3; O43518; Q6NT51;
DE   RecName: Full=Homeobox protein BarH-like 2;
GN   Name=BARX2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0042637; P:catagen; IEA:Ensembl.
DR   GO; GO:0014902; P:myotube differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BASI_HUMAN              Reviewed;         385 AA.
AC   P35613; A6NJW1; D3YLG5; Q7Z796; Q8IZL7;
DE   RecName: Full=Basigin;
DE   AltName: Full=5F7;
DE   AltName: Full=Collagenase stimulatory factor;
DE   AltName: Full=Extracellular matrix metalloproteinase inducer;
DE            Short=EMMPRIN;
DE   AltName: Full=Leukocyte activation antigen M6;
DE   AltName: Full=OK blood group antigen;
DE   AltName: Full=Tumor cell-derived collagenase stimulatory factor;
DE            Short=TCSF;
DE   AltName: CD_antigen=CD147;
DE   Flags: Precursor;
GN   Name=BSG; ORFNames=UNQ6505/PRO21383;
DR   GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0046689; P:response to mercury ion; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BASP1_HUMAN             Reviewed;         227 AA.
AC   P80723; B4DJA8; D3DTD5; O43596; Q5U0S0; Q9BWA5;
DE   RecName: Full=Brain acid soluble protein 1;
DE   AltName: Full=22 kDa neuronal tissue-enriched acidic protein;
DE   AltName: Full=Neuronal axonal membrane protein NAP-22;
GN   Name=BASP1; Synonyms=NAP22;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0060539; P:diaphragm development; ISS:UniProtKB.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0008406; P:gonad development; ISS:UniProtKB.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.
DR   GO; GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.
DR   GO; GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.
//
ID   BAT1_HUMAN              Reviewed;         487 AA.
AC   P82251; B2R9A6;
DE   RecName: Full=b(0,+)-type amino acid transporter 1;
DE            Short=b(0,+)AT1;
DE   AltName: Full=Glycoprotein-associated amino acid transporter b0,+AT1;
DE   AltName: Full=Solute carrier family 7 member 9;
GN   Name=SLC7A9; Synonyms=BAT1;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015184; F:L-cystine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015811; P:L-cystine transport; TAS:GOC.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0015804; P:neutral amino acid transport; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   BATF2_HUMAN             Reviewed;         274 AA.
AC   Q8N1L9; D9IC56; Q8NAF4; Q8NAL8; Q96EH4;
DE   RecName: Full=Basic leucine zipper transcriptional factor ATF-like 2;
DE            Short=B-ATF-2;
DE   AltName: Full=Suppressor of AP-1 regulated by IFN;
DE            Short=SARI;
GN   Name=BATF2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BATF3_HUMAN             Reviewed;         127 AA.
AC   Q9NR55;
DE   RecName: Full=Basic leucine zipper transcriptional factor ATF-like 3;
DE            Short=B-ATF-3;
DE   AltName: Full=21 kDa small nuclear factor isolated from T-cells;
DE   AltName: Full=Jun dimerization protein p21SNFT;
GN   Name=BATF3; Synonyms=SNFT;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   BATF_HUMAN              Reviewed;         125 AA.
AC   Q16520;
DE   RecName: Full=Basic leucine zipper transcriptional factor ATF-like;
DE   AltName: Full=B-cell-activating transcription factor;
DE            Short=B-ATF;
DE   AltName: Full=SF-HT-activated gene 2 protein;
DE            Short=SFA-2;
GN   Name=BATF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:UniProtKB.
DR   GO; GO:0001816; P:cytokine production; ISS:UniProtKB.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0002320; P:lymphoid progenitor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072539; P:T-helper 17 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072540; P:T-helper 17 cell lineage commitment; ISS:UniProtKB.
DR   GO; GO:0045064; P:T-helper 2 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BAZ1A_HUMAN             Reviewed;        1556 AA.
AC   Q9NRL2; Q9NZ15; Q9P065; Q9UIG1; Q9Y3V3;
DE   RecName: Full=Bromodomain adjacent to zinc finger domain protein 1A;
DE   AltName: Full=ATP-dependent chromatin-remodeling protein;
DE   AltName: Full=ATP-utilizing chromatin assembly and remodeling factor 1;
DE            Short=hACF1;
DE   AltName: Full=CHRAC subunit ACF1;
DE   AltName: Full=Williams syndrome transcription factor-related chromatin-remodeling factor 180;
DE            Short=WCRF180;
DE   AltName: Full=hWALp1;
GN   Name=BAZ1A; Synonyms=ACF1, WCRF180; ORFNames=HSPC317;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:BHF-UCL.
//
ID   BAX_HUMAN               Reviewed;         192 AA.
AC   Q07812; A8K4W1; P55269; Q07814; Q07815; Q8WZ49; Q9NR76; Q9NYG7;
AC   Q9UCZ6; Q9UCZ7; Q9UQD6;
DE   RecName: Full=Apoptosis regulator BAX;
DE   AltName: Full=Bcl-2-like protein 4;
DE            Short=Bcl2-L-4;
GN   Name=BAX; Synonyms=BCL2L4;
DR   GO; GO:0051434; F:BH3 domain binding; IDA:UniProtKB.
DR   GO; GO:0015267; F:channel activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:HGNC.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:HGNC.
DR   GO; GO:0097296; P:activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IDA:HGNC.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:1902263; P:apoptotic process involved in embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:1902262; P:apoptotic process involved in patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:HGNC.
DR   GO; GO:0001783; P:B cell apoptotic process; IDA:HGNC.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0002358; P:B cell homeostatic proliferation; IEA:Ensembl.
DR   GO; GO:0002352; P:B cell negative selection; IEA:Ensembl.
DR   GO; GO:1990117; P:B cell receptor apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0045136; P:development of secondary sexual characteristics; IEA:Ensembl.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0010248; P:establishment or maintenance of transmembrane electrochemical gradient; IDA:HGNC.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IC:BHF-UCL.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0008053; P:mitochondrial fusion; IDA:HGNC.
DR   GO; GO:0002262; P:myeloid cell homeostasis; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0030264; P:nuclear fragmentation involved in apoptotic nuclear change; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:1902512; P:positive regulation of apoptotic DNA fragmentation; IMP:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IEA:Ensembl.
DR   GO; GO:0002904; P:positive regulation of B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0048087; P:positive regulation of developmental pigmentation; IEA:Ensembl.
DR   GO; GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IDA:HGNC.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0048597; P:post-embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0001844; P:protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IDA:HGNC.
DR   GO; GO:0006808; P:regulation of nitrogen utilization; IEA:Ensembl.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IPI:HGNC.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:BHF-UCL.
DR   GO; GO:0032976; P:release of matrix enzymes from mitochondria; IDA:HGNC.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IDA:HGNC.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:1990009; P:retinal cell apoptotic process; IMP:HGNC.
DR   GO; GO:0046666; P:retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0060011; P:Sertoli cell proliferation; IEA:Ensembl.
DR   GO; GO:0048515; P:spermatid differentiation; IEA:Ensembl.
DR   GO; GO:0001777; P:T cell homeostatic proliferation; IEA:Ensembl.
DR   GO; GO:0070242; P:thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0006927; P:transformed cell apoptotic process; IMP:HGNC.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BAZ1B_HUMAN             Reviewed;        1483 AA.
AC   Q9UIG0; B9EGK3; D3DXE9; O95039; O95247; O95277; Q6P1K4; Q86UJ6;
DE   RecName: Full=Tyrosine-protein kinase BAZ1B;
DE            EC=2.7.10.2;
DE   AltName: Full=Bromodomain adjacent to zinc finger domain protein 1B;
DE   AltName: Full=Williams syndrome transcription factor;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 10 protein;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 9 protein;
DE   AltName: Full=hWALp2;
GN   Name=BAZ1B; Synonyms=WBSC10, WBSCR10, WBSCR9, WSTF;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0035173; F:histone kinase activity; IDA:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0071884; F:vitamin D receptor activator activity; IMP:BHF-UCL.
DR   GO; GO:0042809; F:vitamin D receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:BHF-UCL.
DR   GO; GO:0034725; P:DNA replication-dependent nucleosome disassembly; IMP:BHF-UCL.
DR   GO; GO:0006302; P:double-strand break repair; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0016572; P:histone phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:2000273; P:positive regulation of receptor activity; IMP:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:BHF-UCL.
//
ID   BAZ2A_HUMAN             Reviewed;        1905 AA.
AC   Q9UIF9; B3KN66; O00536; O15030; Q68DI8; Q96H26;
DE   RecName: Full=Bromodomain adjacent to zinc finger domain protein 2A;
DE   AltName: Full=Transcription termination factor I-interacting protein 5;
DE            Short=TTF-I-interacting protein 5;
DE            Short=Tip5;
DE   AltName: Full=hWALp3;
GN   Name=BAZ2A; Synonyms=KIAA0314, TIP5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; ISS:UniProtKB.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; ISS:UniProtKB.
DR   GO; GO:0006306; P:DNA methylation; ISS:UniProtKB.
DR   GO; GO:0070869; P:heterochromatin assembly involved in chromatin silencing; IEA:Ensembl.
DR   GO; GO:0016575; P:histone deacetylation; ISS:UniProtKB.
DR   GO; GO:0051567; P:histone H3-K9 methylation; IEA:Ensembl.
DR   GO; GO:0070933; P:histone H4 deacetylation; IEA:Ensembl.
DR   GO; GO:0034770; P:histone H4-K20 methylation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   BAZ2B_HUMAN             Reviewed;        2168 AA.
AC   Q9UIF8; D3DPA8; Q96EA1; Q96SQ8; Q9P252; Q9Y4N8;
DE   RecName: Full=Bromodomain adjacent to zinc finger domain protein 2B;
DE   AltName: Full=hWALp4;
GN   Name=BAZ2B; Synonyms=KIAA1476;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:BHF-UCL.
//
ID   BBC3B_HUMAN             Reviewed;         261 AA.
AC   Q96PG8;
DE   RecName: Full=Bcl-2-binding component 3;
DE   AltName: Full=JFY-1;
DE   AltName: Full=p53 up-regulated modulator of apoptosis;
GN   Name=BBC3; Synonyms=PUMA;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   BBC3_HUMAN              Reviewed;         193 AA.
AC   Q9BXH1; B9EGI3; O00171; Q96PG9;
DE   RecName: Full=Bcl-2-binding component 3;
DE   AltName: Full=JFY-1;
DE   AltName: Full=p53 up-regulated modulator of apoptosis;
GN   Name=BBC3; Synonyms=PUMA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:BHF-UCL.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0008340; P:determination of adult lifespan; ISS:BHF-UCL.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; IMP:UniProtKB.
DR   GO; GO:2001056; P:positive regulation of cysteine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0070245; P:positive regulation of thymocyte apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
//
ID   BBIP1_HUMAN             Reviewed;          92 AA.
AC   A8MTZ0; E9PIY9; E9PM41; E9PRI7;
DE   RecName: Full=BBSome-interacting protein 1;
DE   AltName: Full=BBSome-interacting protein of 10 kDa;
GN   Name=BBIP1; Synonyms=BBIP10, NCRNA00081;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   BBOF1_HUMAN             Reviewed;         529 AA.
AC   Q8ND07; Q0P604; Q9H5P8;
DE   RecName: Full=Basal body-orientation factor 1;
DE   AltName: Full=Coiled-coil domain-containing protein 176;
GN   Name=CCDC176; Synonyms=BBOF1, C14orf45;
DR   GO; GO:0044458; P:motile cilium assembly; ISS:UniProtKB.
//
ID   BBS10_HUMAN             Reviewed;         723 AA.
AC   Q8TAM1; Q96CW2; Q9H5D2;
DE   RecName: Full=Bardet-Biedl syndrome 10 protein;
GN   Name=BBS10; Synonyms=C12orf58;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IMP:MGI.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:BHF-UCL.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IMP:MGI.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0001895; P:retina homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BBS12_HUMAN             Reviewed;         710 AA.
AC   Q6ZW61; D3DNX5; Q7Z342; Q7Z482; Q8NAB8;
DE   RecName: Full=Bardet-Biedl syndrome 12 protein;
GN   Name=BBS12; Synonyms=C4orf24;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IMP:MGI.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IMP:MGI.
//
ID   BBS1_HUMAN              Reviewed;         593 AA.
AC   Q8NFJ9; Q32MM9; Q32MN0; Q96SN4;
DE   RecName: Full=Bardet-Biedl syndrome 1 protein;
DE   AltName: Full=BBS2-like protein 2;
GN   Name=BBS1; Synonyms=BBS2L2;
DR   GO; GO:0005113; F:patched binding; IPI:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0005119; F:smoothened binding; IPI:MGI.
DR   GO; GO:0042384; P:cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:MGI.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:BHF-UCL.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0001895; P:retina homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BBS2_HUMAN              Reviewed;         721 AA.
AC   Q9BXC9; Q96CM0; Q96SN9;
DE   RecName: Full=Bardet-Biedl syndrome 2 protein;
GN   Name=BBS2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0030534; P:adult behavior; ISS:BHF-UCL.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:MGI.
DR   GO; GO:0021766; P:hippocampus development; ISS:BHF-UCL.
DR   GO; GO:0032402; P:melanosome transport; ISS:BHF-UCL.
DR   GO; GO:0038108; P:negative regulation of appetite by leptin-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; ISS:BHF-UCL.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; IEA:InterPro.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; ISS:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; ISS:BHF-UCL.
DR   GO; GO:0060296; P:regulation of cilium beat frequency involved in ciliary motility; ISS:BHF-UCL.
DR   GO; GO:0007288; P:sperm axoneme assembly; ISS:BHF-UCL.
DR   GO; GO:0021756; P:striatum development; ISS:BHF-UCL.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BBS5_HUMAN              Reviewed;         341 AA.
AC   Q8N3I7; D3DPC3; Q6PKN0;
DE   RecName: Full=Bardet-Biedl syndrome 5 protein;
GN   Name=BBS5;
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0042384; P:cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0032402; P:melanosome transport; ISS:BHF-UCL.
DR   GO; GO:0044458; P:motile cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BBS7_HUMAN              Reviewed;         715 AA.
AC   Q8IWZ6; Q4W5P8; Q8N581; Q9NVI4;
DE   RecName: Full=Bardet-Biedl syndrome 7 protein;
DE   AltName: Full=BBS2-like protein 1;
GN   Name=BBS7; Synonyms=BBS2L1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0048546; P:digestive tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001654; P:eye development; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0060173; P:limb development; IEA:Ensembl.
DR   GO; GO:0032402; P:melanosome transport; ISS:BHF-UCL.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; IEA:InterPro.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0051877; P:pigment granule aggregation in cell center; ISS:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IPI:MGI.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IPI:MGI.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BBS4_HUMAN              Reviewed;         519 AA.
AC   Q96RK4; B4E178; Q53DZ5; Q8NHU9; Q96H45;
DE   RecName: Full=Bardet-Biedl syndrome 4 protein;
GN   Name=BBS4;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:BHF-UCL.
DR   GO; GO:0034452; F:dynactin binding; IDA:BHF-UCL.
DR   GO; GO:0003777; F:microtubule motor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0030534; P:adult behavior; ISS:BHF-UCL.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.
DR   GO; GO:0042384; P:cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060027; P:convergent extension involved in gastrulation; ISS:BHF-UCL.
DR   GO; GO:0016358; P:dendrite development; ISS:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0021766; P:hippocampus development; ISS:BHF-UCL.
DR   GO; GO:0046907; P:intracellular transport; ISS:BHF-UCL.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IGI:BHF-UCL.
DR   GO; GO:0032402; P:melanosome transport; ISS:BHF-UCL.
DR   GO; GO:0008152; P:metabolic process; IMP:GOC.
DR   GO; GO:0034454; P:microtubule anchoring at centrosome; IMP:BHF-UCL.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:BHF-UCL.
DR   GO; GO:0038108; P:negative regulation of appetite by leptin-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0003085; P:negative regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; ISS:BHF-UCL.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:BHF-UCL.
DR   GO; GO:0051877; P:pigment granule aggregation in cell center; ISS:BHF-UCL.
DR   GO; GO:0045724; P:positive regulation of cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0071539; P:protein localization to centrosome; IMP:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060296; P:regulation of cilium beat frequency involved in ciliary motility; ISS:BHF-UCL.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:BHF-UCL.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0001895; P:retina homeostasis; ISS:BHF-UCL.
DR   GO; GO:0046548; P:retinal rod cell development; ISS:BHF-UCL.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:BHF-UCL.
DR   GO; GO:0050893; P:sensory processing; TAS:BHF-UCL.
DR   GO; GO:0007286; P:spermatid development; ISS:BHF-UCL.
DR   GO; GO:0021756; P:striatum development; ISS:BHF-UCL.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BBX_HUMAN               Reviewed;         941 AA.
AC   Q8WY36; A2RRM7; Q2TAJ1; Q7L3J8; Q7LBY8; Q8NDB0; Q8WY35; Q9H0J6;
DE   RecName: Full=HMG box transcription factor BBX;
DE   AltName: Full=Bobby sox homolog;
DE   AltName: Full=HMG box-containing protein 2;
GN   Name=BBX; Synonyms=HBP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BC11A_HUMAN             Reviewed;         835 AA.
AC   Q9H165; D6W5D7; Q86W14; Q8WU92; Q96JL6; Q9H163; Q9H164; Q9H3G9;
AC   Q9NWA7;
DE   RecName: Full=B-cell lymphoma/leukemia 11A;
DE            Short=BCL-11A;
DE   AltName: Full=B-cell CLL/lymphoma 11A;
DE   AltName: Full=COUP-TF-interacting protein 1;
DE   AltName: Full=Ecotropic viral integration site 9 protein homolog;
DE            Short=EVI-9;
DE   AltName: Full=Zinc finger protein 856;
GN   Name=BCL11A; Synonyms=CTIP1, EVI9, KIAA1809, ZNF856;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0030517; P:negative regulation of axon extension; ISS:BHF-UCL.
DR   GO; GO:0048671; P:negative regulation of collateral sprouting; IMP:BHF-UCL.
DR   GO; GO:2000171; P:negative regulation of dendrite development; IMP:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:BHF-UCL.
DR   GO; GO:0032463; P:negative regulation of protein homooligomerization; IC:BHF-UCL.
DR   GO; GO:0048672; P:positive regulation of collateral sprouting; IMP:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0016925; P:protein sumoylation; ISS:UniProtKB.
DR   GO; GO:0050773; P:regulation of dendrite development; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BC11B_HUMAN             Reviewed;         894 AA.
AC   Q9C0K0; Q9H162;
DE   RecName: Full=B-cell lymphoma/leukemia 11B;
DE            Short=BCL-11B;
DE   AltName: Full=B-cell CLL/lymphoma 11B;
DE   AltName: Full=COUP-TF-interacting protein 2;
DE   AltName: Full=Radiation-induced tumor suppressor gene 1 protein;
DE            Short=hRit1;
GN   Name=BCL11B; Synonyms=CTIP2, RIT1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0046632; P:alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0003334; P:keratinocyte development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0071678; P:olfactory bulb axon guidance; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
DR   GO; GO:0043368; P:positive T cell selection; IEA:Ensembl.
DR   GO; GO:0031077; P:post-embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0010837; P:regulation of keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021773; P:striatal medium spiny neuron differentiation; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0033153; P:T cell receptor V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   BCAM_HUMAN              Reviewed;         628 AA.
AC   P50895; A8MYF9; A9YWT5; A9YWT6; Q86VC7;
DE   RecName: Full=Basal cell adhesion molecule;
DE   AltName: Full=Auberger B antigen;
DE   AltName: Full=B-CAM cell surface glycoprotein;
DE   AltName: Full=F8/G253 antigen;
DE   AltName: Full=Lutheran antigen;
DE   AltName: Full=Lutheran blood group glycoprotein;
DE   AltName: CD_antigen=CD239;
DE   Flags: Precursor;
GN   Name=BCAM; Synonyms=LU, MSK19;
DR   GO; GO:0043236; F:laminin binding; IMP:BHF-UCL.
DR   GO; GO:0005055; F:laminin receptor activity; IMP:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   BCAP_HUMAN              Reviewed;         805 AA.
AC   Q6ZUJ8; Q5TB56; Q5VXJ9; Q8N6J6; Q8NAC8;
DE   RecName: Full=Phosphoinositide 3-kinase adapter protein 1;
DE   AltName: Full=B-cell adapter for phosphoinositide 3-kinase;
DE   AltName: Full=B-cell phosphoinositide 3-kinase adapter protein 1;
GN   Name=PIK3AP1; Synonyms=BCAP;
DR   GO; GO:0036312; F:phosphatidylinositol 3-kinase regulatory subunit binding; ISS:UniProtKB.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034154; P:toll-like receptor 7 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; ISS:UniProtKB.
//
ID   BCAR1_HUMAN             Reviewed;         870 AA.
AC   P56945; B3KWD7; B4DEV4; B4DGB5; B4DIW5; B7Z7X7; E9PCL5; E9PCV2;
AC   F5GXA2; F5GXV6; F5H7Z0; F8WA69; Q6QEF7;
DE   RecName: Full=Breast cancer anti-estrogen resistance protein 1;
DE   AltName: Full=CRK-associated substrate;
DE   AltName: Full=Cas scaffolding protein family member 1;
DE   AltName: Full=p130cas;
GN   Name=BCAR1; Synonyms=CAS, CASS1, CRKAS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007015; P:actin filament organization; IDA:UniProtKB.
DR   GO; GO:0050851; P:antigen receptor-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0051301; P:cell division; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   BCAR3_HUMAN             Reviewed;         825 AA.
AC   O75815; D3DT43; Q5TEW3; Q6UW40; Q9BR50;
DE   RecName: Full=Breast cancer anti-estrogen resistance protein 3;
DE   AltName: Full=Novel SH2-containing protein 2;
DE   AltName: Full=SH2 domain-containing protein 3B;
GN   Name=BCAR3; Synonyms=NSP2, SH2D3B; ORFNames=UNQ271/PRO308;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   BCAS1_HUMAN             Reviewed;         584 AA.
AC   O75363; A0AVG5; Q68CZ3;
DE   RecName: Full=Breast carcinoma-amplified sequence 1;
DE   AltName: Full=Amplified and overexpressed in breast cancer;
DE   AltName: Full=Novel amplified in breast cancer 1;
GN   Name=BCAS1; Synonyms=AIBC1, NABC1;
//
ID   BCAS3_HUMAN             Reviewed;         928 AA.
AC   Q9H6U6; Q17RM0; Q6KF21; Q8IXI6; Q8NDR8; Q8TDL9; Q8TDM1; Q8WY55;
AC   Q9BVF0; Q9H957; Q9H9Y9; Q9NXP4;
DE   RecName: Full=Breast carcinoma-amplified sequence 3;
DE   AltName: Full=GAOB1;
GN   Name=BCAS3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   BCAS4_HUMAN             Reviewed;         211 AA.
AC   Q8TDM0; Q5TD52; Q5TD53; Q5TD54; Q5U5K7; Q5XKE8; Q8IXI7; Q8NEZ6;
AC   Q8TDL9; Q9NX13; Q9Y511;
DE   RecName: Full=Breast carcinoma-amplified sequence 4;
GN   Name=BCAS4;
//
ID   BCAT1_HUMAN             Reviewed;         386 AA.
AC   P54687; B3KY27; B7Z2M5; B7Z5L0; F5H5E4; Q68DQ7; Q96MY9;
DE   RecName: Full=Branched-chain-amino-acid aminotransferase, cytosolic;
DE            Short=BCAT(c);
DE            EC=2.6.1.42;
DE   AltName: Full=Protein ECA39;
GN   Name=BCAT1; Synonyms=BCT1, ECA39;
DR   GO; GO:0004084; F:branched-chain-amino-acid transaminase activity; EXP:Reactome.
DR   GO; GO:0052656; F:L-isoleucine transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052654; F:L-leucine transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052655; F:L-valine transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009082; P:branched-chain amino acid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BCAT2_HUMAN             Reviewed;         392 AA.
AC   O15382; B2RB87; O00269; Q96KG1; Q9BTB6; Q9BUU6;
DE   RecName: Full=Branched-chain-amino-acid aminotransferase, mitochondrial;
DE            Short=BCAT(m);
DE            EC=2.6.1.42;
DE   AltName: Full=Placental protein 18;
DE            Short=PP18;
DE   Flags: Precursor;
GN   Name=BCAT2; Synonyms=BCATM, BCT2, ECA40;
DR   GO; GO:0004084; F:branched-chain-amino-acid transaminase activity; EXP:Reactome.
DR   GO; GO:0052656; F:L-isoleucine transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052654; F:L-leucine transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052655; F:L-valine transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009082; P:branched-chain amino acid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006550; P:isoleucine catabolic process; IEA:Ensembl.
DR   GO; GO:0006551; P:leucine metabolic process; IEA:Ensembl.
DR   GO; GO:0010817; P:regulation of hormone levels; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006573; P:valine metabolic process; IEA:Ensembl.
//
ID   BCCIP_HUMAN             Reviewed;         314 AA.
AC   Q9P287; B3KP45; Q8ND15; Q96GC4; Q9P288;
DE   RecName: Full=BRCA2 and CDKN1A-interacting protein;
DE   AltName: Full=P21- and CDK-associated protein 1;
DE   AltName: Full=Protein TOK-1;
GN   Name=BCCIP; Synonyms=TOK1;
DR   GO; GO:0019207; F:kinase regulator activity; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0061101; P:neuroendocrine cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:MGI.
//
ID   BCD1_HUMAN              Reviewed;         470 AA.
AC   Q9NWK9; B2RBA1; B4DP13; D3DT20; Q9H278; Q9H3X3; Q9NWN0;
DE   RecName: Full=Box C/D snoRNA protein 1;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-75;
DE   AltName: Full=Zinc finger HIT domain-containing protein 6;
GN   Name=ZNHIT6; Synonyms=BCD1, C1orf181;
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000492; P:box C/D snoRNP assembly; IMP:BHF-UCL.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   BCDO1_HUMAN             Reviewed;         547 AA.
AC   Q9HAY6; A0AV48; A0AV50; Q9NVH5;
DE   RecName: Full=Beta,beta-carotene 15,15'-monooxygenase;
DE            EC=1.14.99.36;
DE   AltName: Full=Beta-carotene dioxygenase 1;
GN   Name=BCMO1; Synonyms=BCDO, BCDO1;
DR   GO; GO:0003834; F:beta-carotene 15,15'-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0042574; P:retinal metabolic process; NAS:BHF-UCL.
DR   GO; GO:0001523; P:retinoid metabolic process; IDA:UniProtKB.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0035238; P:vitamin A biosynthetic process; NAS:BHF-UCL.
//
ID   BCDO2_HUMAN             Reviewed;         579 AA.
AC   Q9BYV7; B0YIX5; B4DNC3; E9PBI8; E9PJJ1; Q8IUS0; Q96JC8; Q96JY5;
DE   RecName: Full=Beta,beta-carotene 9',10'-oxygenase;
DE            EC=1.13.11.71;
DE   AltName: Full=B-diox-II;
DE   AltName: Full=Beta-carotene dioxygenase 2;
GN   Name=BCO2; Synonyms=BCDO2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IDA:UniProtKB.
DR   GO; GO:0016121; P:carotene catabolic process; IDA:BHF-UCL.
DR   GO; GO:0016119; P:carotene metabolic process; IDA:UniProtKB.
DR   GO; GO:0016116; P:carotenoid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; ISS:BHF-UCL.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; ISS:BHF-UCL.
DR   GO; GO:0042574; P:retinal metabolic process; NAS:UniProtKB.
DR   GO; GO:0042573; P:retinoic acid metabolic process; NAS:UniProtKB.
//
ID   BCE1_HUMAN              Reviewed;          84 AA.
AC   O60756;
DE   RecName: Full=Putative protein BCE-1;
GN   Name=BCE1;
//
ID   BCKD_HUMAN              Reviewed;         412 AA.
AC   O14874; A8MY43; Q6FGL4; Q96G95; Q96IN5;
DE   RecName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial;
DE            EC=2.7.11.4;
DE   AltName: Full=Branched-chain alpha-ketoacid dehydrogenase kinase;
DE            Short=BCKD-kinase;
DE            Short=BCKDHKIN;
DE   Flags: Precursor;
GN   Name=BCKDK;
DR   GO; GO:0047323; F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; ISS:HGNC.
DR   GO; GO:0009063; P:cellular amino acid catabolic process; NAS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; ISS:HGNC.
//
ID   BCL10_HUMAN             Reviewed;         233 AA.
AC   O95999; Q5VUF1;
DE   RecName: Full=B-cell lymphoma/leukemia 10;
DE   AltName: Full=B-cell CLL/lymphoma 10;
DE            Short=Bcl-10;
DE   AltName: Full=CARD-containing molecule enhancing NF-kappa-B;
DE   AltName: Full=CARD-like apoptotic protein;
DE            Short=hCLAP;
DE   AltName: Full=CED-3/ICH-1 prodomain homologous E10-like regulator;
DE            Short=CIPER;
DE   AltName: Full=Cellular homolog of vCARMEN;
DE            Short=cCARMEN;
DE   AltName: Full=Cellular-E10;
DE            Short=c-E10;
DE   AltName: Full=Mammalian CARD-containing adapter molecule E10;
DE            Short=mE10;
GN   Name=BCL10; Synonyms=CIPER, CLAP;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0043422; F:protein kinase B binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; TAS:UniProtKB.
DR   GO; GO:0001783; P:B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEP:UniProtKB.
DR   GO; GO:0042226; P:interleukin-6 biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0042109; P:lymphotoxin A biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0002906; P:negative regulation of mature B cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0032765; P:positive regulation of mast cell cytokine production; NAS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IPI:UniProtKB.
DR   GO; GO:0050856; P:regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IDA:UniProtKB.
DR   GO; GO:0009620; P:response to fungus; IEA:Ensembl.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IEP:UniProtKB.
DR   GO; GO:0070231; P:T cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IC:UniProtKB.
//
ID   BCL2_HUMAN              Reviewed;         239 AA.
AC   P10415; C9JHD5; P10416; Q13842; Q16197;
DE   RecName: Full=Apoptosis regulator Bcl-2;
GN   Name=BCL2;
DR   GO; GO:0051434; F:BH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0015267; F:channel activity; IDA:BHF-UCL.
DR   GO; GO:0016248; F:channel inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002020; F:protease binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0002326; P:B cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0042100; P:B cell proliferation; IDA:MGI.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0043375; P:CD8-positive, alpha-beta T cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IDA:MGI.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0021747; P:cochlear nucleus development; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0043583; P:ear development; IEA:Ensembl.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:MGI.
DR   GO; GO:0007565; P:female pregnancy; NAS:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0022612; P:gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0032835; P:glomerulus development; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IDA:MGI.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0006582; P:melanin metabolic process; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0014031; P:mesenchymal cell development; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0010523; P:negative regulation of calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0032848; P:negative regulation of cellular pH reduction; IDA:UniProtKB.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IGI:MGI.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051902; P:negative regulation of mitochondrial depolarization; TAS:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0033033; P:negative regulation of myeloid cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:0046671; P:negative regulation of retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; TAS:HGNC.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0048753; P:pigment granule organization; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:MGI.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045636; P:positive regulation of melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0014042; P:positive regulation of neuron maturation; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048743; P:positive regulation of skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:MGI.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IDA:MGI.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0010559; P:regulation of glycoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; ISS:HGNC.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; ISS:HGNC.
DR   GO; GO:0006808; P:regulation of nitrogen utilization; IEA:Ensembl.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
DR   GO; GO:0022898; P:regulation of transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0045069; P:regulation of viral genome replication; IEA:Ensembl.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; NAS:UniProtKB.
DR   GO; GO:0003014; P:renal system process; IEA:Ensembl.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IDA:MGI.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IDA:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IDA:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; NAS:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IDA:HGNC.
DR   GO; GO:0010224; P:response to UV-B; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; IDA:GOC.
//
ID   BCL6B_HUMAN             Reviewed;         479 AA.
AC   Q8N143; Q6PCB4;
DE   RecName: Full=B-cell CLL/lymphoma 6 member B protein;
DE   AltName: Full=Bcl6-associated zinc finger protein;
DE   AltName: Full=Zinc finger protein 62;
GN   Name=BCL6B; Synonyms=BAZF, ZNF62;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   BCL3_HUMAN              Reviewed;         454 AA.
AC   P20749;
DE   RecName: Full=B-cell lymphoma 3 protein;
DE            Short=BCL-3;
DE   AltName: Full=Proto-oncogene BCL3;
GN   Name=BCL3; Synonyms=BCL4, D19S37;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; TAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0019730; P:antimicrobial humoral response; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0002268; P:follicular dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0002467; P:germinal center formation; IEA:Ensembl.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:MGI.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; NAS:UniProtKB.
DR   GO; GO:0002315; P:marginal zone B cell differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0045082; P:positive regulation of interleukin-10 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051101; P:regulation of DNA binding; IEP:UniProtKB.
DR   GO; GO:0042345; P:regulation of NF-kappaB import into nucleus; IEP:UniProtKB.
DR   GO; GO:0010225; P:response to UV-C; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0042088; P:T-helper 1 type immune response; IEA:Ensembl.
DR   GO; GO:0045064; P:T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   BCL6_HUMAN              Reviewed;         706 AA.
AC   P41182; A7E241; B8PSA7; D3DNV5;
DE   RecName: Full=B-cell lymphoma 6 protein;
DE            Short=BCL-6;
DE   AltName: Full=B-cell lymphoma 5 protein;
DE            Short=BCL-5;
DE   AltName: Full=Protein LAZ-3;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 27;
DE   AltName: Full=Zinc finger protein 51;
GN   Name=BCL6; Synonyms=BCL5, LAZ3, ZBTB27, ZNF51;
DR   GO; GO:0003682; F:chromatin binding; IDA:MGI.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0002467; P:germinal center formation; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0002903; P:negative regulation of B cell apoptotic process; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IEA:Ensembl.
DR   GO; GO:0032764; P:negative regulation of mast cell cytokine production; IEA:Ensembl.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0045629; P:negative regulation of T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0002829; P:negative regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IEA:Ensembl.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IGI:UniProtKB.
DR   GO; GO:0002634; P:regulation of germinal center formation; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; NAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043380; P:regulation of memory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042092; P:type 2 immune response; IEA:Ensembl.
//
ID   BCL7A_HUMAN             Reviewed;         210 AA.
AC   Q4VC05; B4DJN6; B7ZB21; Q13843; Q14CT7;
DE   RecName: Full=B-cell CLL/lymphoma 7 protein family member A;
GN   Name=BCL7A;
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   BCL7B_HUMAN             Reviewed;         202 AA.
AC   Q9BQE9; A8K226; C9JWD3; D3DXF0; O43769; Q13845; Q6ZW75;
DE   RecName: Full=B-cell CLL/lymphoma 7 protein family member B;
DE   AltName: Allergen=Hom s 3;
GN   Name=BCL7B;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
//
ID   BCL7C_HUMAN             Reviewed;         217 AA.
AC   Q8WUZ0; O43770; Q6PD89;
DE   RecName: Full=B-cell CLL/lymphoma 7 protein family member C;
GN   Name=BCL7C;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   BCL9L_HUMAN             Reviewed;        1499 AA.
AC   Q86UU0; A1A4C1; Q67FY1; Q6ZWJ0; Q6ZWK2;
DE   RecName: Full=B-cell CLL/lymphoma 9-like protein;
DE            Short=B-cell lymphoma 9-like protein;
DE            Short=BCL9-like protein;
DE   AltName: Full=Protein BCL9-2;
GN   Name=BCL9L; Synonyms=DLNB11;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:MGI.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BCL8_HUMAN              Reviewed;         100 AA.
AC   P0C6P0;
DE   RecName: Full=Putative protein BCL8;
DE   AltName: Full=Neurobeachin pseudogene 1;
GN   Name=NBEAP1; Synonyms=BCL8, BCL8A;
//
ID   BCL9_HUMAN              Reviewed;        1426 AA.
AC   O00512; Q5T489;
DE   RecName: Full=B-cell CLL/lymphoma 9 protein;
DE            Short=B-cell lymphoma 9 protein;
DE            Short=Bcl-9;
DE   AltName: Full=Protein legless homolog;
GN   Name=BCL9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0014908; P:myotube differentiation involved in skeletal muscle regeneration; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
//
ID   BCLF1_HUMAN             Reviewed;         920 AA.
AC   Q9NYF8; A2RU75; B7ZM58; E1P586; Q14673; Q86WU6; Q86WY0;
DE   RecName: Full=Bcl-2-associated transcription factor 1;
DE            Short=Btf;
GN   Name=BCLAF1; Synonyms=BTF, KIAA0164;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:MGI.
DR   GO; GO:2000144; P:positive regulation of DNA-templated transcription, initiation; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0043620; P:regulation of DNA-templated transcription in response to stress; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BCOR2_HUMAN             Reviewed;         145 AA.
AC   Q8N888;
DE   RecName: Full=Putative BCoR-like protein 2;
DE   AltName: Full=BCL-6 corepressor pseudogene 1;
DE   AltName: Full=BCL-6 corepressor-like protein 2;
GN   Name=BCORP1; Synonyms=BCORL2;
//
ID   BCORL_HUMAN             Reviewed;        1711 AA.
AC   Q5H9F3; B5MDQ8; Q5H9F2; Q5H9F4; Q6ZVE0; Q8TEN3; Q9Y528;
DE   RecName: Full=BCL-6 corepressor-like protein 1;
DE            Short=BCoR-L1;
DE            Short=BCoR-like protein 1;
GN   Name=BCORL1;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BCOR_HUMAN              Reviewed;        1755 AA.
AC   Q6W2J9; D3DWB3; D3DWB4; Q29RF6; Q6P4B6; Q7Z2K7; Q8TEB4; Q96DB3;
AC   Q9H232; Q9H233; Q9HCJ7; Q9NXF2;
DE   RecName: Full=BCL-6 corepressor;
DE            Short=BCoR;
GN   Name=BCOR; Synonyms=KIAA1575;
DR   GO; GO:0031072; F:heat shock protein binding; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IMP:UniProtKB.
DR   GO; GO:0000415; P:negative regulation of histone H3-K36 methylation; IMP:UniProtKB.
DR   GO; GO:0051572; P:negative regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0070171; P:negative regulation of tooth mineralization; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; IMP:UniProtKB.
DR   GO; GO:0060021; P:palate development; IMP:UniProtKB.
DR   GO; GO:0065001; P:specification of axis polarity; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BCR_HUMAN               Reviewed;        1271 AA.
AC   P11274; P78501; Q12842; Q4LE80; Q6NZI3;
DE   RecName: Full=Breakpoint cluster region protein;
DE            EC=2.7.11.1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-26;
GN   Name=BCR; Synonyms=BCR1, D22S11;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0016301; F:kinase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043314; P:negative regulation of neutrophil degranulation; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   BCS1_HUMAN              Reviewed;         419 AA.
AC   Q9Y276; B3KTW9; Q7Z2V7;
DE   RecName: Full=Mitochondrial chaperone BCS1;
DE            Short=h-BCS1;
DE   AltName: Full=BCS1-like protein;
GN   Name=BCS1L; Synonyms=BCS1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IMP:UniProtKB.
DR   GO; GO:0033617; P:mitochondrial respiratory chain complex IV assembly; IMP:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
//
ID   BD1L1_HUMAN             Reviewed;        3051 AA.
AC   Q8NFC6; Q6P0M8; Q96AL1; Q9H6G0; Q9NTD6; Q9P2L9;
DE   RecName: Full=Biorientation of chromosomes in cell division protein 1-like 1;
DE   AltName: Full=Protein FAM44A;
GN   Name=BOD1L1; Synonyms=BOD1L, FAM44A, KIAA1327;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
//
ID   BD1L2_HUMAN             Reviewed;         172 AA.
AC   Q8IYS8; B3KXU4; Q8WW13;
DE   RecName: Full=Putative biorientation of chromosomes in cell division protein 1-like 2;
DE   AltName: Full=Putative biorientation of chromosomes in cell division protein 1 pseudogene;
DE   AltName: Full=Putative protein FAM44C;
GN   Name=BOD1L2; Synonyms=BOD1P, FAM44C;
//
ID   BDH2_HUMAN              Reviewed;         245 AA.
AC   Q9BUT1; A8K295; B4DUF6; Q503A0; Q6IA46; Q6UWD3; Q9H8S8; Q9NRX8;
DE   RecName: Full=3-hydroxybutyrate dehydrogenase type 2;
DE            EC=1.1.1.-;
DE            EC=1.1.1.30;
DE   AltName: Full=Dehydrogenase/reductase SDR family member 6;
DE   AltName: Full=Oxidoreductase UCPA;
DE   AltName: Full=R-beta-hydroxybutyrate dehydrogenase;
GN   Name=BDH2; Synonyms=DHRS6; ORFNames=UNQ6308/PRO20933;
DR   GO; GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:HGNC.
DR   GO; GO:0051287; F:NAD binding; IDA:HGNC.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProt.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IDA:HGNC.
DR   GO; GO:0042168; P:heme metabolic process; ISS:UniProtKB.
DR   GO; GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB.
//
ID   BDH_HUMAN               Reviewed;         343 AA.
AC   Q02338; D3DXC0; Q96ET1; Q9BRZ4;
DE   RecName: Full=D-beta-hydroxybutyrate dehydrogenase, mitochondrial;
DE            Short=BDH;
DE            EC=1.1.1.30;
DE   AltName: Full=3-hydroxybutyrate dehydrogenase;
DE   Flags: Precursor;
GN   Name=BDH1; Synonyms=BDH;
DR   GO; GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0046950; P:cellular ketone body metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.
DR   GO; GO:0046952; P:ketone body catabolic process; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0060416; P:response to growth hormone; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BDNF_HUMAN              Reviewed;         247 AA.
AC   P23560; A7LA85; A7LA92; D3DQZ2; Q598Q1; Q6DN19; Q6YNR2; Q6YNR3;
AC   Q9BYY7; Q9UC24;
DE   RecName: Full=Brain-derived neurotrophic factor;
DE            Short=BDNF;
DE   AltName: Full=Abrineurin;
DE   Flags: Precursor;
GN   Name=BDNF;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007412; P:axon target recognition; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0014047; P:glutamate secretion; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0042490; P:mechanoreceptor differentiation; IEA:Ensembl.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:Ensembl.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045843; P:negative regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0008038; P:neuron recognition; IEA:Ensembl.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IDA:BHF-UCL.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0019222; P:regulation of metabolic process; IEA:Ensembl.
DR   GO; GO:0046668; P:regulation of retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0072347; P:response to anesthetic; IEA:Ensembl.
DR   GO; GO:0014076; P:response to fluoxetine; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   BDP1_HUMAN              Reviewed;        2624 AA.
AC   A6H8Y1; Q68DS6; Q68DY5; Q6MZL9; Q6PIM7; Q86W98; Q96LR8; Q9C0H4;
AC   Q9H197; Q9H1A1; Q9HAW1; Q9HAW2; Q9HCY0; Q9ULH9;
DE   RecName: Full=Transcription factor TFIIIB component B'' homolog;
DE   AltName: Full=Transcription factor IIIB 150;
DE            Short=TFIIIB150;
DE   AltName: Full=Transcription factor-like nuclear regulator;
GN   Name=BDP1; Synonyms=KIAA1241, KIAA1689, TFNR;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   BEAN1_HUMAN             Reviewed;         259 AA.
AC   Q3B7T3; B3KPC0; H3BP97;
DE   RecName: Full=Protein BEAN1;
DE   AltName: Full=Brain-expressed protein associating with Nedd4 homolog;
DE            Short=BEAN;
GN   Name=BEAN1;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   BECN1_HUMAN             Reviewed;         450 AA.
AC   Q14457; B2R6N7; O75595; Q9UNA8;
DE   RecName: Full=Beclin-1;
DE   AltName: Full=Coiled-coil myosin-like BCL2-interacting protein;
DE   AltName: Full=Protein GT197;
GN   Name=BECN1; Synonyms=GT197;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IEA:Ensembl.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0071275; P:cellular response to aluminum ion; IEA:Ensembl.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BECN2_HUMAN             Reviewed;         431 AA.
AC   A8MW95; E9KNW0;
DE   RecName: Full=Beclin-2;
GN   Name=BECN1P1; Synonyms=BECN2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:1990172; P:G-protein coupled receptor catabolic process; IMP:UniProtKB.
//
ID   BEGIN_HUMAN             Reviewed;         593 AA.
AC   Q9BUH8; Q9NPU3; Q9P282;
DE   RecName: Full=Brain-enriched guanylate kinase-associated protein;
GN   Name=BEGAIN; Synonyms=KIAA1446;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   BEND2_HUMAN             Reviewed;         799 AA.
AC   Q8NDZ0; E9PFY2; Q4V9S2; Q5JXE5;
DE   RecName: Full=BEN domain-containing protein 2;
GN   Name=BEND2; Synonyms=CXorf20;
//
ID   BEND3_HUMAN             Reviewed;         828 AA.
AC   Q5T5X7; A2RRH2; Q9HCL9;
DE   RecName: Full=BEN domain-containing protein 3;
GN   Name=BEND3; Synonyms=KIAA1553;
//
ID   BEND4_HUMAN             Reviewed;         534 AA.
AC   Q6ZU67; A1A5D6; A1A5D7; C9JQZ5; Q58A26; Q58A27;
DE   RecName: Full=BEN domain-containing protein 4;
DE   AltName: Full=Coiled-coil domain-containing protein 4;
GN   Name=BEND4; Synonyms=CCDC4;
//
ID   BEND5_HUMAN             Reviewed;         421 AA.
AC   Q7L4P6; D3DQ27; Q96A62; Q9HAI3;
DE   RecName: Full=BEN domain-containing protein 5;
GN   Name=BEND5; Synonyms=C1orf165;
//
ID   BEND6_HUMAN             Reviewed;         279 AA.
AC   Q5SZJ8; Q4G0W8; Q8N662; Q96NS6;
DE   RecName: Full=BEN domain-containing protein 6;
GN   Name=BEND6; Synonyms=C6orf65;
//
ID   BEND7_HUMAN             Reviewed;         519 AA.
AC   Q8N7W2; Q5SYY7; Q5SYY8; Q5SYY9; Q8N5T7;
DE   RecName: Full=BEN domain-containing protein 7;
GN   Name=BEND7; Synonyms=C10orf30;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   BEST1_HUMAN             Reviewed;         585 AA.
AC   O76090; A8K0W6; B7Z3J8; B7Z736; O75904; Q53YQ9; Q8IUR9; Q8IZ80;
DE   RecName: Full=Bestrophin-1;
DE   AltName: Full=TU15B;
DE   AltName: Full=Vitelliform macular dystrophy protein 2;
GN   Name=BEST1; Synonyms=VMD2;
DR   GO; GO:0005254; F:chloride channel activity; IDA:MGI.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:MGI.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0030321; P:transepithelial chloride transport; IDA:HGNC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   BEST2_HUMAN             Reviewed;         509 AA.
AC   Q8NFU1; Q53YQ8; Q9NXP0;
DE   RecName: Full=Bestrophin-2;
DE   AltName: Full=Vitelliform macular dystrophy 2-like protein 1;
GN   Name=BEST2; Synonyms=VMD2L1;
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:1902476; P:chloride transmembrane transport; ISS:GOC.
DR   GO; GO:0051899; P:membrane depolarization; ISS:HGNC.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:HGNC.
//
ID   BEST3_HUMAN             Reviewed;         668 AA.
AC   Q8N1M1; B5MDI8; Q53YQ7; Q8N356; Q8NFT9; Q9BR80;
DE   RecName: Full=Bestrophin-3;
DE   AltName: Full=Vitelliform macular dystrophy 2-like protein 3;
GN   Name=BEST3; Synonyms=VMD2L3;
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0043271; P:negative regulation of ion transport; IEA:Ensembl.
//
ID   BEST4_HUMAN             Reviewed;         473 AA.
AC   Q8NFU0; Q5JR93;
DE   RecName: Full=Bestrophin-4;
DE   AltName: Full=Vitelliform macular dystrophy 2-like protein 2;
GN   Name=BEST4; Synonyms=VMD2L2;
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
//
ID   BET1L_HUMAN             Reviewed;         111 AA.
AC   Q9NYM9; B3KMY0;
DE   RecName: Full=BET1-like protein;
DE   AltName: Full=Golgi SNARE with a size of 15 kDa;
DE            Short=GOS-15;
DE            Short=GS15;
DE   AltName: Full=Vesicle transport protein GOS15;
GN   Name=BET1L; Synonyms=GS15;
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:HGNC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:HGNC.
//
ID   BET1_HUMAN              Reviewed;         118 AA.
AC   O15155;
DE   RecName: Full=BET1 homolog;
DE            Short=hBET1;
DE   AltName: Full=Golgi vesicular membrane-trafficking protein p18;
GN   Name=BET1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:Ensembl.
//
ID   BETAT_HUMAN             Reviewed;         198 AA.
AC   Q6UXH0; Q9NQZ1;
DE   RecName: Full=Betatrophin;
DE   AltName: Full=Angiopoietin-like protein 8;
DE   AltName: Full=Lipasin;
DE   Flags: Precursor;
GN   Name=C19orf80; Synonyms=Angptl8; ORFNames=UNQ599/PRO1185;
DR   GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0010954; P:positive regulation of protein processing; IDA:MGI.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0050746; P:regulation of lipoprotein metabolic process; IMP:MGI.
DR   GO; GO:0070328; P:triglyceride homeostasis; IGI:MGI.
DR   GO; GO:0044342; P:type B pancreatic cell proliferation; ISS:UniProtKB.
//
ID   BEX1_HUMAN              Reviewed;         125 AA.
AC   Q9HBH7; A0AVN1; A8K4J3; Q9NZ33;
DE   RecName: Full=Protein BEX1;
DE   AltName: Full=Brain-expressed X-linked protein 1;
GN   Name=BEX1;
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   BEX2_HUMAN              Reviewed;         128 AA.
AC   Q9BXY8; B2R574; D3DXA2; F5H7H5; Q5JVV9;
DE   RecName: Full=Protein BEX2;
DE   AltName: Full=Brain-expressed X-linked protein 2;
DE            Short=hBex2;
GN   Name=BEX2;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
//
ID   BEX3_HUMAN              Reviewed;         111 AA.
AC   Q00994; B2RD17; D3DXA3; Q5JQT4; Q5JQT5;
DE   RecName: Full=Protein BEX3;
DE   AltName: Full=Brain-expressed X-linked protein 3;
DE   AltName: Full=Nerve growth factor receptor-associated protein 1;
DE   AltName: Full=Ovarian granulosa cell 13.0 kDa protein HGR74;
DE   AltName: Full=p75NTR-associated cell death executor;
GN   Name=NGFRAP1; Synonyms=BEX3, DXS6984E, NADE;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:GOC.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
//
ID   BEX4_HUMAN              Reviewed;         120 AA.
AC   Q9NWD9;
DE   RecName: Full=Protein BEX4;
DE   AltName: Full=BEX1-like protein 1;
DE   AltName: Full=Brain-expressed X-linked protein 4;
DE   AltName: Full=Nerve growth factor receptor-associated protein 3;
GN   Name=BEX4; Synonyms=BEXL1, NADE3;
//
ID   BEX5_HUMAN              Reviewed;         111 AA.
AC   Q5H9J7; Q569J0; Q56A74;
DE   RecName: Full=Protein BEX5;
DE   AltName: Full=Brain-expressed X-linked protein 5;
DE   AltName: Full=NGFRAP1-like protein 1;
DE   AltName: Full=Nerve growth factor receptor-associated protein 2;
GN   Name=BEX5; Synonyms=NADE2, NGFRAP1L1;
//
ID   BFAR_HUMAN              Reviewed;         450 AA.
AC   Q9NZS9; A8K4Z9; D3DUG8;
DE   RecName: Full=Bifunctional apoptosis regulator;
DE   AltName: Full=RING finger protein 47;
GN   Name=BFAR; Synonyms=BAR, RNF47;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.
//
ID   BFSP1_HUMAN             Reviewed;         665 AA.
AC   Q12934; O43595; O76034; O95676; Q8IVZ6; Q9HBX4;
DE   RecName: Full=Filensin;
DE   AltName: Full=Beaded filament structural protein 1;
DE   AltName: Full=Lens fiber cell beaded-filament structural protein CP 115;
DE            Short=CP115;
DE   AltName: Full=Lens intermediate filament-like heavy;
DE            Short=LIFL-H;
GN   Name=BFSP1;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
//
ID   BFSP2_HUMAN             Reviewed;         415 AA.
AC   Q13515; Q14D32; Q9HBW5;
DE   RecName: Full=Phakinin;
DE   AltName: Full=49 kDa cytoskeletal protein;
DE   AltName: Full=Beaded filament structural protein 2;
DE   AltName: Full=Lens fiber cell beaded filament protein CP 47;
DE            Short=CP47;
DE   AltName: Full=Lens fiber cell beaded filament protein CP 49;
DE            Short=CP49;
DE   AltName: Full=Lens intermediate filament-like light;
DE            Short=LIFL-L;
GN   Name=BFSP2;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   BGAL_HUMAN              Reviewed;         677 AA.
AC   P16278; B2R7H8; B7Z6B0; P16279;
DE   RecName: Full=Beta-galactosidase;
DE            EC=3.2.1.23;
DE   AltName: Full=Acid beta-galactosidase;
DE            Short=Lactase;
DE   AltName: Full=Elastin receptor 1;
DE   Flags: Precursor;
GN   Name=GLB1; Synonyms=ELNR1;
DR   GO; GO:0004565; F:beta-galactosidase activity; TAS:UniProtKB.
DR   GO; GO:0016936; F:galactoside binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019388; P:galactose catabolic process; IEA:Ensembl.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   BGAT_HUMAN              Reviewed;         354 AA.
AC   P16442; B0JDB9; O14758; Q14490; Q53I57; Q6ISD4; Q6KFZ2; Q70V27;
AC   Q99484; Q99485; Q9NY01; Q9UQ68; Q9UQ69;
DE   RecName: Full=Histo-blood group ABO system transferase;
DE   AltName: Full=Fucosylglycoprotein 3-alpha-galactosyltransferase;
DE   AltName: Full=Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase;
DE   AltName: Full=Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase;
DE            EC=2.4.1.40;
DE   AltName: Full=Glycoprotein-fucosylgalactoside alpha-galactosyltransferase;
DE            EC=2.4.1.37;
DE   AltName: Full=Histo-blood group A transferase;
DE            Short=A transferase;
DE   AltName: Full=Histo-blood group B transferase;
DE            Short=B transferase;
DE   AltName: Full=NAGAT;
DE   Contains:
DE     RecName: Full=Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form;
GN   Name=ABO;
DR   GO; GO:0004381; F:fucosylgalactoside 3-alpha-galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004380; F:glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   BGH3_HUMAN              Reviewed;         683 AA.
AC   Q15582; D3DQB1; O14471; O14472; O14476; O43216; O43217; O43218;
AC   O43219; Q53XM1;
DE   RecName: Full=Transforming growth factor-beta-induced protein ig-h3;
DE            Short=Beta ig-h3;
DE   AltName: Full=Kerato-epithelin;
DE   AltName: Full=RGD-containing collagen-associated protein;
DE            Short=RGD-CAP;
DE   Flags: Precursor;
GN   Name=TGFBI; Synonyms=BIGH3;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   BGLR_HUMAN              Reviewed;         651 AA.
AC   P08236; B4E1F6; E9PCV0; Q549U0; Q96CL9;
DE   RecName: Full=Beta-glucuronidase;
DE            EC=3.2.1.31;
DE   AltName: Full=Beta-G1;
DE   Flags: Precursor;
GN   Name=GUSB;
DR   GO; GO:0004566; F:beta-glucuronidase activity; TAS:Reactome.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BGP11_HUMAN             Reviewed;         273 AA.
AC   Q6P575;
DE   RecName: Full=Putative inactive beta-glucuronidase protein GUSBP11;
DE   AltName: Full=Beta-glucuronidase pseudogene 11;
GN   Name=GUSBP11;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   BHA09_HUMAN             Reviewed;         235 AA.
AC   Q7RTU4; A8MSH6;
DE   RecName: Full=Class A basic helix-loop-helix protein 9;
DE            Short=bHLHa9;
DE   AltName: Full=Class F basic helix-loop-helix factor 42;
DE            Short=bHLHf42;
GN   Name=BHLHA9; Synonyms=BHLHF42;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BHA15_HUMAN             Reviewed;         189 AA.
AC   Q7RTS1; A4D271; Q14DE4;
DE   RecName: Full=Class A basic helix-loop-helix protein 15;
DE            Short=bHLHa15;
DE   AltName: Full=Class B basic helix-loop-helix protein 8;
DE            Short=bHLHb8;
DE   AltName: Full=Muscle, intestine and stomach expression 1;
DE            Short=MIST-1;
GN   Name=BHLHA15; Synonyms=BHLHB8, MIST1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BHE23_HUMAN             Reviewed;         225 AA.
AC   Q8NDY6; B2RP69;
DE   RecName: Full=Class E basic helix-loop-helix protein 23;
DE            Short=bHLHe23;
DE   AltName: Full=Class B basic helix-loop-helix protein 4;
DE            Short=bHLHb4;
GN   Name=BHLHE23; Synonyms=BHLHB4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046671; P:negative regulation of retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048050; P:post-embryonic eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0046548; P:retinal rod cell development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BHE22_HUMAN             Reviewed;         381 AA.
AC   Q8NFJ8;
DE   RecName: Full=Class E basic helix-loop-helix protein 22;
DE            Short=bHLHe22;
DE   AltName: Full=Class B basic helix-loop-helix protein 5;
DE            Short=bHLHb5;
DE   AltName: Full=Trinucleotide repeat-containing gene 20 protein;
GN   Name=BHLHE22; Synonyms=BHLHB5, TNRC20;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0021960; P:anterior commissure morphogenesis; IEA:Ensembl.
DR   GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR   GO; GO:0021540; P:corpus callosum morphogenesis; IEA:Ensembl.
DR   GO; GO:0021957; P:corticospinal tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0060040; P:retinal bipolar neuron differentiation; IEA:Ensembl.
//
ID   BHE40_HUMAN             Reviewed;         412 AA.
AC   O14503; Q96TD3;
DE   RecName: Full=Class E basic helix-loop-helix protein 40;
DE            Short=bHLHe40;
DE   AltName: Full=Class B basic helix-loop-helix protein 2;
DE            Short=bHLHb2;
DE   AltName: Full=Differentially expressed in chondrocytes protein 1;
DE            Short=DEC1;
DE   AltName: Full=Enhancer-of-split and hairy-related protein 2;
DE            Short=SHARP-2;
DE   AltName: Full=Stimulated by retinoic acid gene 13 protein;
GN   Name=BHLHE40; Synonyms=BHLHB2, DEC1, SHARP2, STRA13;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0043426; F:MRF binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   BHE41_HUMAN             Reviewed;         482 AA.
AC   Q9C0J9; A2I2N8;
DE   RecName: Full=Class E basic helix-loop-helix protein 41;
DE            Short=bHLHe41;
DE   AltName: Full=Class B basic helix-loop-helix protein 3;
DE            Short=bHLHb3;
DE   AltName: Full=Differentially expressed in chondrocytes protein 2;
DE            Short=hDEC2;
DE   AltName: Full=Enhancer-of-split and hairy-related protein 1;
DE            Short=SHARP-1;
GN   Name=BHLHE41; Synonyms=BHLHB3, DEC2, SHARP1;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; ISS:BHF-UCL.
DR   GO; GO:0043426; F:MRF binding; ISS:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; ISS:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
//
ID   BHLH9_HUMAN             Reviewed;         547 AA.
AC   Q6PI77; Q9C0G2;
DE   RecName: Full=Protein BHLHb9;
DE            Short=bHLHb9;
DE   AltName: Full=Transcription regulator of 60 kDa;
DE            Short=p60TRP;
GN   Name=BHLHB9; Synonyms=KIAA1701;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProt.
DR   GO; GO:0007611; P:learning or memory; ISS:UniProt.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProt.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProt.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProt.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:UniProt.
//
ID   BHMT1_HUMAN             Reviewed;         406 AA.
AC   Q93088; Q9UNI9;
DE   RecName: Full=Betaine--homocysteine S-methyltransferase 1;
DE            EC=2.1.1.5;
GN   Name=BHMT;
DR   GO; GO:0047150; F:betaine-homocysteine S-methyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0008898; F:S-adenosylmethionine-homocysteine S-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006579; P:amino-acid betaine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006479; P:protein methylation; NAS:UniProtKB.
DR   GO; GO:0050666; P:regulation of homocysteine metabolic process; NAS:UniProtKB.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   BHMT2_HUMAN             Reviewed;         363 AA.
AC   Q9H2M3; B7Z516; Q9NXX7;
DE   RecName: Full=S-methylmethionine--homocysteine S-methyltransferase BHMT2;
DE            Short=SMM-hcy methyltransferase;
DE            EC=2.1.1.10;
DE   AltName: Full=Betaine--homocysteine S-methyltransferase 2;
GN   Name=BHMT2;
DR   GO; GO:0047150; F:betaine-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008898; F:S-adenosylmethionine-homocysteine S-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
//
ID   BI1_HUMAN               Reviewed;         237 AA.
AC   P55061; B2R5M4; O14938; Q643A7; Q96J50;
DE   RecName: Full=Bax inhibitor 1;
DE            Short=BI-1;
DE   AltName: Full=Testis-enhanced gene transcript protein;
DE   AltName: Full=Transmembrane BAX inhibitor motif-containing protein 6;
GN   Name=TMBIM6; Synonyms=BI1, TEGT;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   BI2L1_HUMAN             Reviewed;         511 AA.
AC   Q9UHR4; A4D268; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9Y2M8;
DE   RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1;
DE            Short=BAI1-associated protein 2-like protein 1;
DE   AltName: Full=Insulin receptor tyrosine kinase substrate;
GN   Name=BAIAP2L1; Synonyms=IRTKS;
DR   GO; GO:0070064; F:proline-rich region binding; IDA:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IEA:InterPro.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   BI2L2_HUMAN             Reviewed;         529 AA.
AC   Q6UXY1; B0QYE2; Q96BG7;
DE   RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2;
DE            Short=BAI1-associated protein 2-like protein 2;
DE   AltName: Full=Planar intestinal- and kidney-specific BAR domain protein;
DE            Short=Pinkbar;
GN   Name=BAIAP2L2; ORFNames=UNQ9336/PRO34007;
DR   GO; GO:0005543; F:phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; ISS:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   BICC1_HUMAN             Reviewed;         974 AA.
AC   Q9H694;
DE   RecName: Full=Protein bicaudal C homolog 1;
DE            Short=Bic-C;
GN   Name=BICC1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
//
ID   BICD1_HUMAN             Reviewed;         975 AA.
AC   Q96G01; A8K2C3; F8W113; O43892; O43893;
DE   RecName: Full=Protein bicaudal D homolog 1;
DE            Short=Bic-D 1;
GN   Name=BICD1;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; IDA:BHF-UCL.
DR   GO; GO:0034452; F:dynactin binding; IDA:BHF-UCL.
DR   GO; GO:0045502; F:dynein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031871; F:proteinase activated receptor binding; ISS:BHF-UCL.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0008298; P:intracellular mRNA localization; NAS:UniProtKB.
DR   GO; GO:0072393; P:microtubule anchoring at microtubule organizing center; ISS:BHF-UCL.
DR   GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; IMP:BHF-UCL.
DR   GO; GO:1900275; P:negative regulation of phospholipase C activity; ISS:BHF-UCL.
DR   GO; GO:1900737; P:negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; IDA:BHF-UCL.
DR   GO; GO:1900276; P:regulation of proteinase activated receptor activity; ISS:BHF-UCL.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0034063; P:stress granule assembly; ISS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IMP:BHF-UCL.
//
ID   BICD2_HUMAN             Reviewed;         824 AA.
AC   Q8TD16; O75181; Q5TBQ2; Q5TBQ3; Q96LH2; Q9BT84; Q9H561;
DE   RecName: Full=Protein bicaudal D homolog 2;
DE            Short=Bic-D 2;
GN   Name=BICD2; Synonyms=KIAA0699;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; ISS:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0072393; P:microtubule anchoring at microtubule organizing center; ISS:BHF-UCL.
DR   GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; ISS:BHF-UCL.
//
ID   BICR1_HUMAN             Reviewed;         573 AA.
AC   Q6ZP65; A8MUC8; O95000;
DE   RecName: Full=Bicaudal D-related protein 1;
DE            Short=BICD-related protein 1;
DE            Short=BICDR-1;
DE   AltName: Full=Coiled-coil domain-containing protein 64A;
GN   Name=CCDC64; Synonyms=BICDR1;
DR   GO; GO:0034452; F:dynactin binding; ISS:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
DR   GO; GO:0055107; P:Golgi to secretory granule transport; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
//
ID   BICR2_HUMAN             Reviewed;         508 AA.
AC   A1A5D9; Q658L9;
DE   RecName: Full=Bicaudal D-related protein 2;
DE            Short=BICD-related protein 2;
DE            Short=BICDR-2;
DE   AltName: Full=Coiled-coil domain-containing protein 64B;
GN   Name=CCDC64B; Synonyms=BICDR2;
//
ID   BID_HUMAN               Reviewed;         195 AA.
AC   P55957; Q549M7; Q71T04; Q7Z4M9; Q8IY86;
DE   RecName: Full=BH3-interacting domain death agonist;
DE   AltName: Full=p22 BID;
DE            Short=BID;
DE   Contains:
DE     RecName: Full=BH3-interacting domain death agonist p15;
DE     AltName: Full=p15 BID;
DE   Contains:
DE     RecName: Full=BH3-interacting domain death agonist p13;
DE     AltName: Full=p13 BID;
DE   Contains:
DE     RecName: Full=BH3-interacting domain death agonist p11;
DE     AltName: Full=p11 BID;
GN   Name=BID;
DR   GO; GO:0005123; F:death receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0090150; P:establishment of protein localization to membrane; IDA:BHF-UCL.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:ProtInc.
DR   GO; GO:0034349; P:glial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0051402; P:neuron apoptotic process; TAS:HGNC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:1902108; P:regulation of mitochondrial membrane permeability involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:HGNC.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; TAS:UniProtKB.
//
ID   BIEA_HUMAN              Reviewed;         296 AA.
AC   P53004; A8K747; O95019; Q86UX0; Q96QL4; Q9BRW8;
DE   RecName: Full=Biliverdin reductase A;
DE            Short=BVR A;
DE            EC=1.3.1.24;
DE   AltName: Full=Biliverdin-IX alpha-reductase;
DE   Flags: Precursor;
GN   Name=BLVRA; Synonyms=BLVR, BVR;
DR   GO; GO:0004074; F:biliverdin reductase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042167; P:heme catabolic process; TAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BIG1_HUMAN              Reviewed;        1849 AA.
AC   Q9Y6D6; Q9NV46; Q9UFV2; Q9UNL0;
DE   RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1;
DE            Short=Brefeldin A-inhibited GEP 1;
DE   AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1;
DE   AltName: Full=p200 ARF guanine nucleotide exchange factor;
DE   AltName: Full=p200 ARF-GEP1;
GN   Name=ARFGEF1; Synonyms=ARFGEP1, BIG1;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IDA:UniProtKB.
DR   GO; GO:0010256; P:endomembrane system organization; IMP:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0034259; P:negative regulation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0090284; P:positive regulation of protein glycosylation in Golgi; IMP:UniProtKB.
DR   GO; GO:0090303; P:positive regulation of wound healing; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:RefGenome.
//
ID   BIG2_HUMAN              Reviewed;        1785 AA.
AC   Q9Y6D5; Q5TFT9; Q9NTS1;
DE   RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 2;
DE            Short=Brefeldin A-inhibited GEP 2;
DE   AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2;
GN   Name=ARFGEF2; Synonyms=ARFGEP2, BIG2;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0050811; F:GABA receptor binding; ISS:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IDA:UniProtKB.
DR   GO; GO:0010256; P:endomembrane system organization; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0001881; P:receptor recycling; IDA:UniProtKB.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:RefGenome.
//
ID   BIG3_HUMAN              Reviewed;        2177 AA.
AC   Q5TH69; Q76MU8; Q8N4Y4; Q96CH9; Q96P46; Q9ULH6;
DE   RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 3;
GN   Name=ARFGEF3; Synonyms=BIG3, C6orf92, KIAA1244;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:RefGenome.
//
ID   BIK_HUMAN               Reviewed;         160 AA.
AC   Q13323; Q16582; Q6FH93;
DE   RecName: Full=Bcl-2-interacting killer;
DE   AltName: Full=Apoptosis inducer NBK;
DE   AltName: Full=BIP1;
DE   AltName: Full=BP4;
GN   Name=BIK; Synonyms=NBK;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   BIN1_HUMAN              Reviewed;         593 AA.
AC   O00499; O00297; O00545; O43867; O60552; O60553; O60554; O60555;
AC   O75514; O75515; O75516; O75517; O75518; Q659B7; Q92944; Q99688;
DE   RecName: Full=Myc box-dependent-interacting protein 1;
DE   AltName: Full=Amphiphysin II;
DE   AltName: Full=Amphiphysin-like protein;
DE   AltName: Full=Box-dependent myc-interacting protein 1;
DE   AltName: Full=Bridging integrator 1;
GN   Name=BIN1; Synonyms=AMPHL;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048156; F:tau protein binding; IPI:Alzheimers_University_of_Toronto.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0060988; P:lipid tube assembly; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0071156; P:regulation of cell cycle arrest; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BIN2_HUMAN              Reviewed;         565 AA.
AC   Q9UBW5; Q86VV0; Q9NWK4; Q9UKN4;
DE   RecName: Full=Bridging integrator 2;
DE   AltName: Full=Breast cancer-associated protein 1;
GN   Name=BIN2; Synonyms=BRAP1;
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0097320; P:membrane tubulation; IDA:UniProtKB.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IMP:UniProtKB.
DR   GO; GO:0071800; P:podosome assembly; IMP:UniProtKB.
//
ID   BIN3_HUMAN              Reviewed;         253 AA.
AC   Q9NQY0; Q9BVG2; Q9NVY9;
DE   RecName: Full=Bridging integrator 3;
GN   Name=BIN3;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007015; P:actin filament organization; NAS:UniProtKB.
DR   GO; GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0000910; P:cytokinesis; NAS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:0009826; P:unidimensional cell growth; IMP:UniProtKB.
//
ID   BINCA_HUMAN             Reviewed;         228 AA.
AC   Q96LW7; Q5BJH8; Q9BSY2;
DE   RecName: Full=Bcl10-interacting CARD protein;
DE            Short=BinCARD;
GN   Name=C9orf89;
DR   GO; GO:0050700; F:CARD domain binding; NAS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; NAS:UniProtKB.
//
ID   BIRC1_HUMAN             Reviewed;        1403 AA.
AC   Q13075; B9EG72; E9PHD1; O75857; Q13730; Q59GI6; Q8TDZ4; Q99796;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 1;
DE   AltName: Full=Neuronal apoptosis inhibitory protein;
GN   Name=NAIP; Synonyms=BIRC1;
DR   GO; GO:0005524; F:ATP binding; IMP:UniProtKB.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   BIRC3_HUMAN             Reviewed;         604 AA.
AC   Q13489; Q16628; Q9HC27; Q9UP46;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 3;
DE            EC=6.3.2.-;
DE   AltName: Full=Apoptosis inhibitor 2;
DE            Short=API2;
DE   AltName: Full=C-IAP2;
DE   AltName: Full=IAP homolog C;
DE   AltName: Full=Inhibitor of apoptosis protein 1;
DE            Short=IAP-1;
DE            Short=hIAP-1;
DE            Short=hIAP1;
DE   AltName: Full=RING finger protein 49;
DE   AltName: Full=TNFR2-TRAF-signaling complex protein 1;
GN   Name=BIRC3; Synonyms=API2, IAP1, MIHC, RNF49;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070266; P:necroptotic process; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0060546; P:negative regulation of necroptotic process; IEA:Ensembl.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0038061; P:NIK/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:GOC.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000116; P:regulation of cysteine-type endopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; TAS:UniProtKB.
DR   GO; GO:0060544; P:regulation of necroptotic process; IMP:UniProtKB.
DR   GO; GO:0070424; P:regulation of nucleotide-binding oligomerization domain containing signaling pathway; TAS:UniProtKB.
DR   GO; GO:0039535; P:regulation of RIG-I signaling pathway; TAS:UniProtKB.
DR   GO; GO:0034121; P:regulation of toll-like receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   BIRC2_HUMAN             Reviewed;         618 AA.
AC   Q13490; B4E026; Q16516; Q4TTG0;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 2;
DE            EC=6.3.2.-;
DE   AltName: Full=C-IAP1;
DE   AltName: Full=IAP homolog B;
DE   AltName: Full=Inhibitor of apoptosis protein 2;
DE            Short=IAP-2;
DE            Short=hIAP-2;
DE            Short=hIAP2;
DE   AltName: Full=RING finger protein 48;
DE   AltName: Full=TNFR2-TRAF-signaling complex protein 2;
GN   Name=BIRC2; Synonyms=API1, IAP2, MIHB, RNF48;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070266; P:necroptotic process; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0038061; P:NIK/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:1902524; P:positive regulation of protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:1902523; P:positive regulation of protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:1902527; P:positive regulation of protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:2000116; P:regulation of cysteine-type endopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; TAS:UniProtKB.
DR   GO; GO:0060544; P:regulation of necroptotic process; IMP:UniProtKB.
DR   GO; GO:0070424; P:regulation of nucleotide-binding oligomerization domain containing signaling pathway; TAS:UniProtKB.
DR   GO; GO:0039535; P:regulation of RIG-I signaling pathway; TAS:UniProtKB.
DR   GO; GO:0034121; P:regulation of toll-like receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   BIRC5_HUMAN             Reviewed;         142 AA.
AC   O15392; A2SUH6; B2R4R1; Q2I3N8; Q4VGX0; Q53F61; Q5MGC6; Q6FHL2;
AC   Q75SP2; Q9P2W8;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 5;
DE   AltName: Full=Apoptosis inhibitor 4;
DE   AltName: Full=Apoptosis inhibitor survivin;
GN   Name=BIRC5; Synonyms=API4, IAP4;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
DR   GO; GO:0050897; F:cobalt ion binding; NAS:UniProtKB.
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008536; F:Ran GTPase binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0051303; P:establishment of chromosome localization; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0031536; P:positive regulation of exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0031503; P:protein complex localization; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031577; P:spindle checkpoint; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BIRC6_HUMAN             Reviewed;        4857 AA.
AC   Q9NR09; Q9ULD1;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 6;
DE            EC=6.3.2.-;
DE   AltName: Full=BIR repeat-containing ubiquitin-conjugating enzyme;
DE            Short=BRUCE;
DE   AltName: Full=Ubiquitin-conjugating BIR domain enzyme apollon;
DE            Short=APOLLON;
GN   Name=BIRC6; Synonyms=KIAA1289;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IMP:GOC.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEA:Ensembl.
//
ID   BIRC7_HUMAN             Reviewed;         298 AA.
AC   Q96CA5; Q9BQV0; Q9H2A8; Q9HAP7;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 7;
DE            EC=6.3.2.-;
DE   AltName: Full=Kidney inhibitor of apoptosis protein;
DE            Short=KIAP;
DE   AltName: Full=Livin;
DE   AltName: Full=Melanoma inhibitor of apoptosis protein;
DE            Short=ML-IAP;
DE   AltName: Full=RING finger protein 50;
DE   Contains:
DE     RecName: Full=Baculoviral IAP repeat-containing protein 7 30kDa subunit;
DE              Short=Truncated livin;
DE              Short=p30-Livin;
DE              Short=tLivin;
GN   Name=BIRC7; Synonyms=KIAP, LIVIN, MLIAP, RNF50;
GN   ORFNames=UNQ5800/PRO19607/PRO21344;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007257; P:activation of JUN kinase activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070247; P:regulation of natural killer cell apoptotic process; IDA:UniProtKB.
//
ID   BIRC8_HUMAN             Reviewed;         236 AA.
AC   Q96P09; Q6IPY1; Q96RW5;
DE   RecName: Full=Baculoviral IAP repeat-containing protein 8;
DE   AltName: Full=Inhibitor of apoptosis-like protein 2;
DE            Short=IAP-like protein 2;
DE            Short=ILP-2;
DE   AltName: Full=Testis-specific inhibitor of apoptosis;
GN   Name=BIRC8; Synonyms=ILP2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   BIVM_HUMAN              Reviewed;         503 AA.
AC   Q86UB2; Q2M1J2; Q9NXM4;
DE   RecName: Full=Basic immunoglobulin-like variable motif-containing protein;
GN   Name=BIVM;
//
ID   BKRB1_HUMAN             Reviewed;         353 AA.
AC   P46663; A8K7F5; Q546S7; Q8N0Y8;
DE   RecName: Full=B1 bradykinin receptor;
DE            Short=B1R;
DE            Short=BK-1 receptor;
GN   Name=BDKRB1; Synonyms=BRADYB1;
DR   GuidetoPHARMACOLOGY; 41; -.
DR   GO; GO:0004947; F:bradykinin receptor activity; TAS:ProtInc.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:InterPro.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
//
ID   BKRB2_HUMAN             Reviewed;         391 AA.
AC   P30411;
DE   RecName: Full=B2 bradykinin receptor;
DE            Short=B2R;
DE            Short=BK-2 receptor;
GN   Name=BDKRB2; Synonyms=BKR2;
DR   GuidetoPHARMACOLOGY; 42; -.
DR   GO; GO:0004947; F:bradykinin receptor activity; IDA:BHF-UCL.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0031702; F:type 1 angiotensin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:BHF-UCL.
DR   GO; GO:0008015; P:blood circulation; NAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IC:BHF-UCL.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:1902239; P:negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0043114; P:regulation of vascular permeability; IC:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IC:BHF-UCL.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0006939; P:smooth muscle contraction; IC:BHF-UCL.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
DR   GO; GO:0042310; P:vasoconstriction; IEA:InterPro.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   BL1S1_HUMAN             Reviewed;         153 AA.
AC   P78537; A1L4Q9; Q6NZ45;
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 1;
DE            Short=BLOC-1 subunit 1;
DE   AltName: Full=GCN5-like protein 1;
DE   AltName: Full=Protein RT14;
GN   Name=BLOC1S1; Synonyms=BLOS1, GCN5L1, RT14;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009060; P:aerobic respiration; IMP:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0018394; P:peptidyl-lysine acetylation; IMP:UniProtKB.
DR   GO; GO:0060155; P:platelet dense granule organization; NAS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
//
ID   BL1S2_HUMAN             Reviewed;         142 AA.
AC   Q6QNY1; B4DQV2; Q5W040; Q8WUI8;
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 2;
DE            Short=BLOC-1 subunit 2;
DE   AltName: Full=Centrosome-associated protein;
GN   Name=BLOC1S2; Synonyms=BLOS2, CEAP;
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0007020; P:microtubule nucleation; NAS:UniProtKB.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0060155; P:platelet dense granule organization; NAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   BL1S3_HUMAN             Reviewed;         202 AA.
AC   Q6QNY0; B2RXB8;
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 3;
DE            Short=BLOC-1 subunit 3;
GN   Name=BLOC1S3; Synonyms=BLOS3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0035646; P:endosome to melanosome transport; IDA:UniProtKB.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; IDA:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0043473; P:pigmentation; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; IMP:UniProtKB.
DR   GO; GO:0060155; P:platelet dense granule organization; NAS:UniProtKB.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IEA:Ensembl.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0033299; P:secretion of lysosomal enzymes; IEA:Ensembl.
//
ID   BL1S4_HUMAN             Reviewed;         217 AA.
AC   Q9NUP1; Q6NVY6; Q96G84;
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 4;
DE            Short=BLOC-1 subunit 4;
DE   AltName: Full=Protein cappuccino homolog;
GN   Name=BLOC1S4; Synonyms=CNO;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
//
ID   BL1S5_HUMAN             Reviewed;         187 AA.
AC   Q8TDH9; B4DVM2; Q0VDJ6; Q0VDJ7; Q5THS1; Q68D56; Q8N5F9; Q9NU16;
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 5;
DE            Short=BLOC-1 subunit 5;
DE   AltName: Full=Protein Muted homolog;
GN   Name=BLOC1S5; Synonyms=MUTED;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0035646; P:endosome to melanosome transport; IDA:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0050942; P:positive regulation of pigment cell differentiation; IDA:UniProtKB.
//
ID   BL1S6_HUMAN             Reviewed;         172 AA.
AC   Q9UL45;
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 6;
DE            Short=BLOC-1 subunit 6;
DE   AltName: Full=Pallid protein homolog;
DE   AltName: Full=Pallidin;
DE   AltName: Full=Syntaxin 13-interacting protein;
GN   Name=BLOC1S6; Synonyms=PA, PLDN;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; TAS:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0035646; P:endosome to melanosome transport; IDA:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; IDA:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IEA:Ensembl.
DR   GO; GO:0050942; P:positive regulation of pigment cell differentiation; IDA:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0033299; P:secretion of lysosomal enzymes; IEA:Ensembl.
DR   GO; GO:0016081; P:synaptic vesicle docking involved in exocytosis; NAS:UniProtKB.
//
ID   BLACE_HUMAN             Reviewed;         179 AA.
AC   A4D250;
DE   RecName: Full=B-cell acute lymphoblastic leukemia-expressed protein;
GN   Name=BLACE;
//
ID   BLCAP_HUMAN             Reviewed;          87 AA.
AC   P62952; A2A2K7; O60629; Q9D3B5;
DE   RecName: Full=Bladder cancer-associated protein;
DE   AltName: Full=Bladder cancer 10 kDa protein;
DE            Short=Bc10;
GN   Name=BLCAP; Synonyms=BC10;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   BLID_HUMAN              Reviewed;         108 AA.
AC   Q8IZY5; A1L416;
DE   RecName: Full=BH3-like motif-containing cell death inducer;
DE   AltName: Full=Breast cancer cell protein 2;
GN   Name=BLID; Synonyms=BRCC2;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   BLK_HUMAN               Reviewed;         505 AA.
AC   P51451; Q16291; Q96IN1;
DE   RecName: Full=Tyrosine-protein kinase Blk;
DE            EC=2.7.10.2;
DE   AltName: Full=B lymphocyte kinase;
DE   AltName: Full=p55-Blk;
GN   Name=BLK;
DR   GuidetoPHARMACOLOGY; 1940; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.
//
ID   BLMH_HUMAN              Reviewed;         455 AA.
AC   Q13867; B2R796; Q53F86; Q9UER9;
DE   RecName: Full=Bleomycin hydrolase;
DE            Short=BH;
DE            Short=BLM hydrolase;
DE            Short=BMH;
DE            EC=3.4.22.40;
GN   Name=BLMH;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:ProtInc.
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
//
ID   BLML_HUMAN              Reviewed;         500 AA.
AC   A8MY62;
DE   RecName: Full=Putative beta-lactamase-like 1;
GN   Name=LACTBL1;
//
ID   BLM_HUMAN               Reviewed;        1417 AA.
AC   P54132; Q52M96;
DE   RecName: Full=Bloom syndrome protein;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA helicase, RecQ-like type 2;
DE            Short=RecQ2;
DE   AltName: Full=RecQ protein-like 3;
GN   Name=BLM; Synonyms=RECQ2, RECQL3;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:Ensembl.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0000405; F:bubble DNA binding; IDA:UniProtKB.
DR   GO; GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.
DR   GO; GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0046632; P:alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0072757; P:cellular response to camptothecin; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0072711; P:cellular response to hydroxyurea; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000729; P:DNA double-strand break processing; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; NAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:GOC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; NAS:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; NAS:UniProtKB.
DR   GO; GO:0000085; P:mitotic G2 phase; NAS:UniProtKB.
DR   GO; GO:0051782; P:negative regulation of cell division; IMP:UniProtKB.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IMP:UniProtKB.
DR   GO; GO:0045950; P:negative regulation of mitotic recombination; IEA:Ensembl.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0051098; P:regulation of binding; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IMP:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IDA:UniProtKB.
DR   GO; GO:0048478; P:replication fork protection; NAS:UniProtKB.
DR   GO; GO:0010165; P:response to X-ray; IDA:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IEA:Ensembl.
//
ID   BLNK_HUMAN              Reviewed;         456 AA.
AC   Q8WV28; O75498; O75499; Q2MD49;
DE   RecName: Full=B-cell linker protein;
DE   AltName: Full=B-cell adapter containing a SH2 domain protein;
DE   AltName: Full=B-cell adapter containing a Src homology 2 domain protein;
DE   AltName: Full=Cytoplasmic adapter protein;
DE   AltName: Full=Src homology 2 domain-containing leukocyte protein of 65 kDa;
DE            Short=SLP-65;
GN   Name=BLNK; Synonyms=BASH, SLP65;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:UniProtKB.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; TAS:ProtInc.
DR   GO; GO:0030183; P:B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IDA:GOC.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:GOC.
//
ID   BLVRB_HUMAN             Reviewed;         206 AA.
AC   P30043; A6NKD8; B2R5C6; P32078; P53005; Q32LZ2;
DE   RecName: Full=Flavin reductase (NADPH);
DE            Short=FR;
DE            EC=1.5.1.30;
DE   AltName: Full=Biliverdin reductase B;
DE            Short=BVR-B;
DE            EC=1.3.1.24;
DE   AltName: Full=Biliverdin-IX beta-reductase;
DE   AltName: Full=Green heme-binding protein;
DE            Short=GHBP;
DE   AltName: Full=NADPH-dependent diaphorase;
DE   AltName: Full=NADPH-flavin reductase;
DE            Short=FLR;
GN   Name=BLVRB; Synonyms=FLR;
DR   GO; GO:0004074; F:biliverdin reductase activity; IDA:UniProtKB.
DR   GO; GO:0042602; F:riboflavin reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0042167; P:heme catabolic process; IDA:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BM2KL_HUMAN             Reviewed;         411 AA.
AC   Q5H9B9;
DE   RecName: Full=Putative BMP-2-inducible kinase-like protein;
GN   Name=BMP2KL;
//
ID   BMAL1_HUMAN             Reviewed;         626 AA.
AC   O00327; A2I2N6; A8K645; B5ME11; B7WPG7; D3DQW6; O00313; O00314;
AC   O00315; O00316; O00317; Q4G136; Q8IUT4; Q99631; Q99649;
DE   RecName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP3;
DE   AltName: Full=Brain and muscle ARNT-like 1;
DE   AltName: Full=Class E basic helix-loop-helix protein 5;
DE            Short=bHLHe5;
DE   AltName: Full=Member of PAS protein 3;
DE   AltName: Full=PAS domain-containing protein 3;
DE   AltName: Full=bHLH-PAS protein JAP3;
GN   Name=ARNTL; Synonyms=BHLHE5, BMAL1, MOP3, PASD3;
DR   GO; GO:0017162; F:aryl hydrocarbon receptor binding; IPI:BHF-UCL.
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0090403; P:oxidative stress-induced premature senescence; ISS:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:2001016; P:positive regulation of skeletal muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:2000772; P:regulation of cellular senescence; ISS:UniProtKB.
DR   GO; GO:0042634; P:regulation of hair cycle; IMP:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0050767; P:regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:2000074; P:regulation of type B pancreatic cell development; ISS:UniProtKB.
DR   GO; GO:0051775; P:response to redox state; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
//
ID   BMAL2_HUMAN             Reviewed;         636 AA.
AC   Q8WYA1; B7Z429; F5H402; Q8WYA2; Q8WYA3; Q8WYA4; Q96J63; Q9H2M4;
AC   Q9NS70; Q9NYQ4; Q9NYQ5;
DE   RecName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 2;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP9;
DE   AltName: Full=Brain and muscle ARNT-like 2;
DE   AltName: Full=CYCLE-like factor;
DE            Short=CLIF;
DE   AltName: Full=Class E basic helix-loop-helix protein 6;
DE            Short=bHLHe6;
DE   AltName: Full=Member of PAS protein 9;
DE   AltName: Full=PAS domain-containing protein 9;
GN   Name=ARNTL2; Synonyms=BHLHE6, BMAL2, CLIF, MOP9, PASD9;
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007623; P:circadian rhythm; IDA:MGI.
DR   GO; GO:0009649; P:entrainment of circadian clock; NAS:UniProtKB.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   BMF_HUMAN               Reviewed;         184 AA.
AC   Q96LC9; Q2M396; Q6NT30; Q6NT56; Q6P9F6; Q7Z7D4; Q7Z7D5; Q9H7K7;
DE   RecName: Full=Bcl-2-modifying factor;
GN   Name=BMF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043276; P:anoikis; IDA:MGI.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; ISS:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; ISS:BHF-UCL.
//
ID   BMI1_HUMAN              Reviewed;         326 AA.
AC   P35226; Q16030; Q5T8Z3; Q96F37;
DE   RecName: Full=Polycomb complex protein BMI-1;
DE   AltName: Full=Polycomb group RING finger protein 4;
DE   AltName: Full=RING finger protein 51;
GN   Name=BMI1; Synonyms=PCGF4, RNF51;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0030097; P:hemopoiesis; IEP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0007379; P:segment specification; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BMP10_HUMAN             Reviewed;         424 AA.
AC   O95393; Q53R17; Q6NTE0;
DE   RecName: Full=Bone morphogenetic protein 10;
DE            Short=BMP-10;
DE   Flags: Precursor;
GN   Name=BMP10;
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0033612; F:receptor serine/threonine kinase binding; IDA:UniProtKB.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007512; P:adult heart development; ISS:BHF-UCL.
DR   GO; GO:0055009; P:atrial cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IC:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060347; P:heart trabecula formation; ISS:BHF-UCL.
DR   GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060298; P:positive regulation of sarcomere organization; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; ISS:BHF-UCL.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
//
ID   BMP15_HUMAN             Reviewed;         392 AA.
AC   O95972; Q17RM6; Q5JST1; Q9UMS1;
DE   RecName: Full=Bone morphogenetic protein 15;
DE            Short=BMP-15;
DE   AltName: Full=Growth/differentiation factor 9B;
DE            Short=GDF-9B;
DE   Flags: Precursor;
GN   Name=BMP15; Synonyms=GDF9B;
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0060016; P:granulosa cell development; IEA:InterPro.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   BMP1_HUMAN              Reviewed;         986 AA.
AC   P13497; A8K6F5; B2RN46; D3DSR0; Q13292; Q13872; Q14874; Q99421;
AC   Q99422; Q99423; Q9UL38;
DE   RecName: Full=Bone morphogenetic protein 1;
DE            Short=BMP-1;
DE            EC=3.4.24.19;
DE   AltName: Full=Mammalian tolloid protein;
DE            Short=mTld;
DE   AltName: Full=Procollagen C-proteinase;
DE            Short=PCP;
DE   Flags: Precursor;
GN   Name=BMP1; Synonyms=PCOLC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:Reactome.
DR   GO; GO:0008237; F:metallopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001502; P:cartilage condensation; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:MGI.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BMP2K_HUMAN             Reviewed;        1161 AA.
AC   Q9NSY1; O94791; Q4W5H2; Q8IYF2; Q8N2G7; Q8NHG9; Q9NTG8;
DE   RecName: Full=BMP-2-inducible protein kinase;
DE            Short=BIKe;
DE            EC=2.7.11.1;
GN   Name=BMP2K; Synonyms=BIKE; ORFNames=HRIHFB2017;
DR   GuidetoPHARMACOLOGY; 1941; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019208; F:phosphatase regulator activity; IEA:Ensembl.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:Ensembl.
//
ID   BMP2_HUMAN              Reviewed;         396 AA.
AC   P12643;
DE   RecName: Full=Bone morphogenetic protein 2;
DE            Short=BMP-2;
DE   AltName: Full=Bone morphogenetic protein 2A;
DE            Short=BMP-2A;
DE   Flags: Precursor;
GN   Name=BMP2; Synonyms=BMP2A;
DR   GO; GO:0070700; F:BMP receptor binding; IDA:MGI.
DR   GO; GO:0019211; F:phosphatase activator activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IDA:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:AgBase.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0003130; P:BMP signaling pathway involved in heart induction; IDA:BHF-UCL.
DR   GO; GO:0030282; P:bone mineralization; ISS:UniProtKB.
DR   GO; GO:0035630; P:bone mineralization involved in bone maturation; IDA:BHF-UCL.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; ISS:UniProtKB.
DR   GO; GO:0035051; P:cardiocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0045165; P:cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IDA:BHF-UCL.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IDA:AgBase.
DR   GO; GO:0060128; P:corticotropin hormone secreting cell differentiation; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; ISS:UniProtKB.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; ISS:UniProtKB.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; IDA:UniProtKB.
DR   GO; GO:0072138; P:mesenchymal cell proliferation involved in ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0060485; P:mesenchyme development; IMP:BHF-UCL.
DR   GO; GO:0032348; P:negative regulation of aldosterone biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0051042; P:negative regulation of calcium-independent cell-cell adhesion; IDA:AgBase.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEP:AgBase.
DR   GO; GO:2000726; P:negative regulation of cardiac muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:HGNC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000065; P:negative regulation of cortisol biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010894; P:negative regulation of steroid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0003308; P:negative regulation of Wnt signaling pathway involved in heart development; IDA:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:MGI.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:GOC.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060039; P:pericardium development; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:BHF-UCL.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:MGI.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:DFLAT.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:DFLAT.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0042482; P:positive regulation of odontogenesis; ISS:UniProtKB.
DR   GO; GO:0045778; P:positive regulation of ossification; IDA:MGI.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; ISS:UniProtKB.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:DFLAT.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010922; P:positive regulation of phosphatase activity; IDA:MGI.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:1901522; P:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060804; P:positive regulation of Wnt signaling pathway by BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:DFLAT.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IEA:Ensembl.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0001666; P:response to hypoxia; ISS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0021537; P:telencephalon development; IDA:MGI.
DR   GO; GO:0021978; P:telencephalon regionalization; ISS:UniProtKB.
DR   GO; GO:0060129; P:thyroid-stimulating hormone-secreting cell differentiation; ISS:UniProtKB.
//
ID   BMP3B_HUMAN             Reviewed;         478 AA.
AC   P55107; Q5VSQ8; Q9UCX6;
DE   RecName: Full=Bone morphogenetic protein 3B;
DE            Short=BMP-3B;
DE   AltName: Full=Bone-inducing protein;
DE            Short=BIP;
DE   AltName: Full=Growth/differentiation factor 10;
DE            Short=GDF-10;
DE   Flags: Precursor;
GN   Name=GDF10; Synonyms=BMP3B;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   BMP3_HUMAN              Reviewed;         472 AA.
AC   P12645; Q4VAS5;
DE   RecName: Full=Bone morphogenetic protein 3;
DE            Short=BMP-3;
DE   AltName: Full=Bone morphogenetic protein 3A;
DE            Short=BMP-3A;
DE   AltName: Full=Osteogenin;
DE   Flags: Precursor;
GN   Name=BMP3; Synonyms=BMP3A;
DR   GO; GO:0070700; F:BMP receptor binding; IPI:MGI.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   BMP4_HUMAN              Reviewed;         408 AA.
AC   P12644; Q9UM80;
DE   RecName: Full=Bone morphogenetic protein 4;
DE            Short=BMP-4;
DE   AltName: Full=Bone morphogenetic protein 2B;
DE            Short=BMP-2B;
DE   Flags: Precursor;
GN   Name=BMP4; Synonyms=BMP2B, DVR4;
DR   GO; GO:0070700; F:BMP receptor binding; IDA:MGI.
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0005125; F:cytokine activity; IDA:MGI.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0003130; P:BMP signaling pathway involved in heart induction; IMP:BHF-UCL.
DR   GO; GO:0071893; P:BMP signaling pathway involved in nephric duct formation; IDA:UniProtKB.
DR   GO; GO:0061151; P:BMP signaling pathway involved in renal system segmentation; ISS:UniProtKB.
DR   GO; GO:0061149; P:BMP signaling pathway involved in ureter morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060442; P:branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IDA:UniProtKB.
DR   GO; GO:0060433; P:bronchus development; IDA:MGI.
DR   GO; GO:0060503; P:bud dilation involved in lung branching; IDA:MGI.
DR   GO; GO:0060449; P:bud elongation involved in lung branching; IEA:Ensembl.
DR   GO; GO:0003279; P:cardiac septum development; TAS:BHF-UCL.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0060197; P:cloacal septation; IEA:Ensembl.
DR   GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0060363; P:cranial suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0035993; P:deltoid tuberosity development; ISS:UniProtKB.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0003197; P:endocardial cushion development; TAS:BHF-UCL.
DR   GO; GO:0001958; P:endochondral ossification; ISS:UniProtKB.
DR   GO; GO:0060502; P:epithelial cell proliferation involved in lung morphogenesis; IDA:MGI.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IDA:MGI.
DR   GO; GO:0060684; P:epithelial-mesenchymal cell signaling; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0072104; P:glomerular capillary formation; ISS:UniProtKB.
DR   GO; GO:0072015; P:glomerular visceral epithelial cell development; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IDA:UniProtKB.
DR   GO; GO:0060113; P:inner ear receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0048392; P:intermediate mesodermal cell differentiation; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IMP:UniProtKB.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IDA:MGI.
DR   GO; GO:0060425; P:lung morphogenesis; IDA:MGI.
DR   GO; GO:0002320; P:lymphoid progenitor cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0030225; P:macrophage differentiation; IDA:DFLAT.
DR   GO; GO:0060592; P:mammary gland formation; IEA:Ensembl.
DR   GO; GO:0072161; P:mesenchymal cell differentiation involved in kidney development; IEA:Ensembl.
DR   GO; GO:0072198; P:mesenchymal cell proliferation involved in ureter development; IEA:Ensembl.
DR   GO; GO:0072138; P:mesenchymal cell proliferation involved in ureteric bud development; IEA:Ensembl.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IDA:UniProtKB.
DR   GO; GO:0007500; P:mesodermal cell fate determination; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; IEP:UniProtKB.
DR   GO; GO:0072205; P:metanephric collecting duct development; ISS:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IDA:DFLAT.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0072097; P:negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0090191; P:negative regulation of branching involved in ureteric bud morphogenesis; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:HGNC.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.
DR   GO; GO:2000137; P:negative regulation of cell proliferation involved in heart morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0072125; P:negative regulation of glomerular mesangial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0090194; P:negative regulation of glomerulus development; IDA:UniProtKB.
DR   GO; GO:0033088; P:negative regulation of immature T cell proliferation in thymus; IMP:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0072200; P:negative regulation of mesenchymal cell proliferation involved in ureter development; IDA:UniProtKB.
DR   GO; GO:2000007; P:negative regulation of metanephric comma-shaped body morphogenesis; IDA:UniProtKB.
DR   GO; GO:2000005; P:negative regulation of metanephric S-shaped body morphogenesis; IDA:UniProtKB.
DR   GO; GO:0045839; P:negative regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IDA:MGI.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0060686; P:negative regulation of prostatic bud formation; IEA:Ensembl.
DR   GO; GO:0045843; P:negative regulation of striated muscle tissue development; IDA:MGI.
DR   GO; GO:0033085; P:negative regulation of T cell differentiation in thymus; IMP:BHF-UCL.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IGI:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0061047; P:positive regulation of branching involved in lung morphogenesis; ISS:UniProtKB.
DR   GO; GO:0055020; P:positive regulation of cardiac muscle fiber development; IMP:BHF-UCL.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:MGI.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:MGI.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:2000105; P:positive regulation of DNA-dependent DNA replication; IDA:BHF-UCL.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045606; P:positive regulation of epidermal cell differentiation; IDA:UniProt.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0090184; P:positive regulation of kidney development; IDA:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IDA:MGI.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:MGI.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IDA:MGI.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
DR   GO; GO:0061155; P:pulmonary artery endothelial tube morphogenesis; IDA:UniProtKB.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0010453; P:regulation of cell fate commitment; IDA:UniProt.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051150; P:regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0072001; P:renal system development; IEP:UniProtKB.
DR   GO; GO:0003014; P:renal system process; IEA:Ensembl.
DR   GO; GO:0003139; P:secondary heart field specification; IMP:BHF-UCL.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0048745; P:smooth muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEP:UniProtKB.
DR   GO; GO:0010159; P:specification of organ position; IEA:Ensembl.
DR   GO; GO:0072101; P:specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0021537; P:telencephalon development; IDA:MGI.
DR   GO; GO:0021978; P:telencephalon regionalization; IEA:Ensembl.
DR   GO; GO:0035990; P:tendon cell differentiation; ISS:UniProtKB.
DR   GO; GO:0060438; P:trachea development; IDA:MGI.
DR   GO; GO:0060440; P:trachea formation; IEA:Ensembl.
DR   GO; GO:0003323; P:type B pancreatic cell development; IDA:BHF-UCL.
DR   GO; GO:0072192; P:ureter epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072193; P:ureter smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; IDA:MGI.
//
ID   BMP5_HUMAN              Reviewed;         454 AA.
AC   P22003; Q9H547; Q9NTM5;
DE   RecName: Full=Bone morphogenetic protein 5;
DE            Short=BMP-5;
DE   Flags: Precursor;
GN   Name=BMP5;
DR   GO; GO:0070700; F:BMP receptor binding; IPI:MGI.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0032348; P:negative regulation of aldosterone biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000065; P:negative regulation of cortisol biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; NAS:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; NAS:BHF-UCL.
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0071676; P:negative regulation of mononuclear cell migration; NAS:BHF-UCL.
DR   GO; GO:0010894; P:negative regulation of steroid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:1900006; P:positive regulation of dendrite development; IDA:BHF-UCL.
DR   GO; GO:2000105; P:positive regulation of DNA-dependent DNA replication; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; NAS:UniProtKB.
DR   GO; GO:0003323; P:type B pancreatic cell development; IDA:BHF-UCL.
//
ID   BMP6_HUMAN              Reviewed;         513 AA.
AC   P22004; Q5TCP3;
DE   RecName: Full=Bone morphogenetic protein 6;
DE            Short=BMP-6;
DE   AltName: Full=VG-1-related protein;
DE            Short=VG-1-R;
DE            Short=VGR-1;
DE   Flags: Precursor;
GN   Name=BMP6; Synonyms=VGR;
DR   GO; GO:0070700; F:BMP receptor binding; IPI:MGI.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IMP:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0032349; P:positive regulation of aldosterone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2000860; P:positive regulation of aldosterone secretion; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:BHF-UCL.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:2000105; P:positive regulation of DNA-dependent DNA replication; NAS:BHF-UCL.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; NAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0003323; P:type B pancreatic cell development; IDA:BHF-UCL.
//
ID   BMP7_HUMAN              Reviewed;         431 AA.
AC   P18075; Q9H512; Q9NTQ7;
DE   RecName: Full=Bone morphogenetic protein 7;
DE            Short=BMP-7;
DE   AltName: Full=Osteogenic protein 1;
DE            Short=OP-1;
DE   AltName: INN=Eptotermin alfa;
DE   Flags: Precursor;
GN   Name=BMP7; Synonyms=OP1;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0071456; P:cellular response to hypoxia; ISS:BHF-UCL.
DR   GO; GO:0016358; P:dendrite development; TAS:BHF-UCL.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; TAS:HGNC.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; IDA:UniProtKB.
DR   GO; GO:0060485; P:mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; IEP:UniProtKB.
DR   GO; GO:0072136; P:metanephric mesenchymal cell proliferation involved in metanephros development; IEA:Ensembl.
DR   GO; GO:0072133; P:metanephric mesenchyme morphogenesis; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEP:UniProtKB.
DR   GO; GO:0070487; P:monocyte aggregation; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:HGNC.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0072125; P:negative regulation of glomerular mesangial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0072040; P:negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis; IEA:Ensembl.
DR   GO; GO:0045839; P:negative regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; ISS:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0060686; P:negative regulation of prostatic bud formation; IEA:Ensembl.
DR   GO; GO:0010664; P:negative regulation of striated muscle cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0072134; P:nephrogenic mesenchyme morphogenesis; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IDA:MGI.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:BHF-UCL.
DR   GO; GO:1900006; P:positive regulation of dendrite development; IDA:BHF-UCL.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:1900106; P:positive regulation of hyaluranon cable assembly; IDA:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:2000121; P:regulation of removal of superoxide radicals; ISS:BHF-UCL.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
//
ID   BMP8A_HUMAN             Reviewed;         402 AA.
AC   Q7Z5Y6; Q5T3A5;
DE   RecName: Full=Bone morphogenetic protein 8A;
DE            Short=BMP-8A;
DE   Flags: Precursor;
GN   Name=BMP8A;
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0002024; P:diet induced thermogenesis; IDA:UniProtKB.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IDA:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:2000505; P:regulation of energy homeostasis; IDA:UniProtKB.
//
ID   BMP8B_HUMAN             Reviewed;         402 AA.
AC   P34820; Q53ZM7; Q9NUF0;
DE   RecName: Full=Bone morphogenetic protein 8B;
DE            Short=BMP-8;
DE            Short=BMP-8B;
DE   AltName: Full=Osteogenic protein 2;
DE            Short=OP-2;
DE   Flags: Precursor;
GN   Name=BMP8B; Synonyms=BMP8;
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   BMPER_HUMAN             Reviewed;         685 AA.
AC   Q8N8U9; A8K1P8; Q8TF36;
DE   RecName: Full=BMP-binding endothelial regulator protein;
DE   AltName: Full=Bone morphogenetic protein-binding endothelial cell precursor-derived regulator;
DE   AltName: Full=Protein crossveinless-2;
DE            Short=hCV2;
DE   Flags: Precursor;
GN   Name=BMPER; Synonyms=KIAA1965;
DR   GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0042118; P:endothelial cell activation; IDA:BHF-UCL.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0010594; P:regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   BMPR2_HUMAN             Reviewed;        1038 AA.
AC   Q13873; Q13161; Q16569; Q4ZG08; Q53SA5; Q585T8;
DE   RecName: Full=Bone morphogenetic protein receptor type-2;
DE            Short=BMP type-2 receptor;
DE            Short=BMPR-2;
DE            EC=2.7.11.30;
DE   AltName: Full=Bone morphogenetic protein receptor type II;
DE            Short=BMP type II receptor;
DE            Short=BMPR-II;
DE   Flags: Precursor;
GN   Name=BMPR2; Synonyms=PPH1;
DR   GuidetoPHARMACOLOGY; 1794; -.
DR   GO; GO:0016362; F:activin receptor activity, type II; TAS:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0032924; P:activin receptor signaling pathway; TAS:GOC.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.
DR   GO; GO:0060840; P:artery development; ISS:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; IEP:BHF-UCL.
DR   GO; GO:0048286; P:lung alveolus development; ISS:BHF-UCL.
DR   GO; GO:0001946; P:lymphangiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060836; P:lymphatic endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0001707; P:mesoderm formation; ISS:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0003085; P:negative regulation of systemic arterial blood pressure; IMP:BHF-UCL.
DR   GO; GO:0045906; P:negative regulation of vasoconstriction; ISS:BHF-UCL.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:0014916; P:regulation of lung blood pressure; IMP:BHF-UCL.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0060841; P:venous blood vessel development; ISS:BHF-UCL.
//
ID   BMR1A_HUMAN             Reviewed;         532 AA.
AC   P36894; A8K6U9; Q8NEN8;
DE   RecName: Full=Bone morphogenetic protein receptor type-1A;
DE            Short=BMP type-1A receptor;
DE            Short=BMPR-1A;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin receptor-like kinase 3;
DE            Short=ALK-3;
DE   AltName: Full=Serine/threonine-protein kinase receptor R5;
DE            Short=SKR5;
DE   AltName: CD_antigen=CD292;
DE   Flags: Precursor;
GN   Name=BMPR1A; Synonyms=ACVRLK3, ALK3;
DR   GuidetoPHARMACOLOGY; 1786; -.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IEA:InterPro.
DR   GO; GO:0004675; F:transmembrane receptor protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0003272; P:endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0060914; P:heart formation; IEA:Ensembl.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048368; P:lateral mesoderm development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0048382; P:mesendoderm development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0001880; P:Mullerian duct regression; IEA:Ensembl.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0021998; P:neural plate mediolateral regionalization; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0048352; P:paraxial mesoderm structural organization; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:HGNC.
DR   GO; GO:0048378; P:regulation of lateral mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   BMR1B_HUMAN             Reviewed;         502 AA.
AC   O00238; B2R953; B4DSV1; P78366;
DE   RecName: Full=Bone morphogenetic protein receptor type-1B;
DE            Short=BMP type-1B receptor;
DE            Short=BMPR-1B;
DE            EC=2.7.11.30;
DE   AltName: CD_antigen=CDw293;
DE   Flags: Precursor;
GN   Name=BMPR1B;
DR   GuidetoPHARMACOLOGY; 1789; -.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0005025; F:transforming growth factor beta receptor activity, type I; IEA:Ensembl.
DR   GO; GO:0004675; F:transmembrane receptor protein serine/threonine kinase activity; IMP:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; NAS:UniProtKB.
DR   GO; GO:0001502; P:cartilage condensation; NAS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0001550; P:ovarian cumulus expansion; ISS:UniProtKB.
DR   GO; GO:0042698; P:ovulation cycle; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IMP:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:HGNC.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
//
ID   BMS1_HUMAN              Reviewed;        1282 AA.
AC   Q14692; Q5QPT5; Q86XJ9;
DE   RecName: Full=Ribosome biogenesis protein BMS1 homolog;
DE   AltName: Full=Ribosome assembly protein BMS1 homolog;
GN   Name=BMS1; Synonyms=BMS1L, KIAA0187;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042255; P:ribosome assembly; ISS:UniProtKB.
//
ID   BMT2_HUMAN              Reviewed;         405 AA.
AC   Q1RMZ1; Q8N3D0; Q96MV7;
DE   RecName: Full=Probable methyltransferase BTM2 homolog;
DE            EC=2.1.1.-;
GN   Name=C7orf60;
DR   GO; GO:0016433; F:rRNA (adenine) methyltransferase activity; IEA:InterPro.
//
ID   BMX_HUMAN               Reviewed;         675 AA.
AC   P51813; A6NIH9; O60564; Q12871;
DE   RecName: Full=Cytoplasmic tyrosine-protein kinase BMX;
DE            EC=2.7.10.2;
DE   AltName: Full=Bone marrow tyrosine kinase gene in chromosome X protein;
DE   AltName: Full=Epithelial and endothelial tyrosine kinase;
DE            Short=ETK;
DE   AltName: Full=NTK38;
GN   Name=BMX;
DR   GuidetoPHARMACOLOGY; 1942; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   BN3D2_HUMAN             Reviewed;         292 AA.
AC   Q7Z5W3; A8K829;
DE   RecName: Full=Pre-miRNA 5'-monophosphate methyltransferase;
DE            EC=2.1.1.-;
DE   AltName: Full=BCDIN3 domain-containing protein;
GN   Name=BCDIN3D;
DR   GO; GO:0008171; F:O-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0010586; P:miRNA metabolic process; IDA:UniProtKB.
DR   GO; GO:2000632; P:negative regulation of pre-miRNA processing; IDA:UniProtKB.
DR   GO; GO:0001510; P:RNA methylation; IDA:UniProtKB.
//
ID   BNC1_HUMAN              Reviewed;         994 AA.
AC   Q01954; Q15840;
DE   RecName: Full=Zinc finger protein basonuclin-1;
GN   Name=BNC1; Synonyms=BNC;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   BNC2_HUMAN              Reviewed;        1099 AA.
AC   Q6ZN30; B1APG9; Q6T3A3; Q8NAR2; Q9H6J0; Q9NXV0;
DE   RecName: Full=Zinc finger protein basonuclin-2;
GN   Name=BNC2;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003416; P:endochondral bone growth; IEA:Ensembl.
DR   GO; GO:0060485; P:mesenchyme development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BNI3L_HUMAN             Reviewed;         219 AA.
AC   O60238; Q5JW63; Q8NF87;
DE   RecName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like;
DE   AltName: Full=Adenovirus E1B19K-binding protein B5;
DE   AltName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A;
DE   AltName: Full=NIP3-like protein X;
DE            Short=NIP3L;
GN   Name=BNIP3L; Synonyms=BNIP3A, BNIP3H, NIX;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005521; F:lamin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IBA:RefGenome.
DR   GO; GO:0035694; P:mitochondrial protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BNIP2_HUMAN             Reviewed;         314 AA.
AC   Q12982; B4DS94;
DE   RecName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2;
GN   Name=BNIP2; Synonyms=NIP2;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IPI:MGI.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
//
ID   BNIP3_HUMAN             Reviewed;         194 AA.
AC   Q12983; O14620; Q96GP0;
DE   RecName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 3;
GN   Name=BNIP3; Synonyms=NIP3;
DR   GO; GO:0051020; F:GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IPI:MGI.
DR   GO; GO:0048102; P:autophagic cell death; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; ISS:UniProtKB.
DR   GO; GO:0071279; P:cellular response to cobalt ion; IMP:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0008626; P:granzyme-mediated apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:1990144; P:intrinsic apoptotic signaling pathway in response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IDA:UniProtKB.
DR   GO; GO:0035694; P:mitochondrial protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0045837; P:negative regulation of membrane potential; IDA:UniProtKB.
DR   GO; GO:0010637; P:negative regulation of mitochondrial fusion; IDA:BHF-UCL.
DR   GO; GO:0051402; P:neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IDA:BHF-UCL.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.
DR   GO; GO:0043243; P:positive regulation of protein complex disassembly; IDA:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IDA:UniProtKB.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BNIPL_HUMAN             Reviewed;         357 AA.
AC   Q7Z465; Q6DK43; Q8TCY7; Q8WYG2;
DE   RecName: Full=Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein;
GN   Name=BNIPL;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0040009; P:regulation of growth rate; IDA:UniProtKB.
//
ID   BOC_HUMAN               Reviewed;        1114 AA.
AC   Q9BWV1; A6NJ30; B2RMS8; D3DN70; Q6UXJ5; Q8N2P7; Q8NF26;
DE   RecName: Full=Brother of CDO;
DE            Short=Protein BOC;
DE   Flags: Precursor;
GN   Name=BOC; ORFNames=UNQ604/PRO1190;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; ISS:HGNC.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   BOD1_HUMAN              Reviewed;         185 AA.
AC   Q96IK1; B4DXH8; Q9BTW1;
DE   RecName: Full=Biorientation of chromosomes in cell division protein 1;
DE   AltName: Full=Biorientation defective protein 1;
DE   AltName: Full=Protein FAM44B;
GN   Name=BOD1; Synonyms=FAM44B;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   BODG_HUMAN              Reviewed;         387 AA.
AC   O75936; B2R8L7; D3DQZ1; Q6IBJ2;
DE   RecName: Full=Gamma-butyrobetaine dioxygenase;
DE            EC=1.14.11.1;
DE   AltName: Full=Gamma-butyrobetaine hydroxylase;
DE            Short=Gamma-BBH;
DE   AltName: Full=Gamma-butyrobetaine,2-oxoglutarate dioxygenase;
GN   Name=BBOX1; Synonyms=BBH, BBOX;
DR   GO; GO:0008336; F:gamma-butyrobetaine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0045329; P:carnitine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BOK_HUMAN               Reviewed;         212 AA.
AC   Q9UMX3;
DE   RecName: Full=Bcl-2-related ovarian killer protein;
DE            Short=hBOK;
DE   AltName: Full=Bcl-2-like protein 9;
DE            Short=Bcl2-L-9;
GN   Name=BOK; Synonyms=BCL2L9;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEP:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:1900119; P:positive regulation of execution phase of apoptosis; IMP:UniProtKB.
//
ID   BOLA1_HUMAN             Reviewed;         137 AA.
AC   Q9Y3E2; B2R7K2; D3DUZ4; Q5QNY0;
DE   RecName: Full=BolA-like protein 1;
DE   AltName: Full=hBolA;
GN   Name=BOLA1; ORFNames=CGI-143;
//
ID   BOLA2_HUMAN             Reviewed;          86 AA.
AC   Q9H3K6; A1L454; A7YDY3;
DE   RecName: Full=BolA-like protein 2;
GN   Name=BOLA2; Synonyms=BOLA2A; ORFNames=My016;
GN   and
GN   Name=BOLA2B;
//
ID   BOLA3_HUMAN             Reviewed;         107 AA.
AC   Q53S33; G3XAB0;
DE   RecName: Full=BolA-like protein 3;
GN   Name=BOLA3;
//
ID   BOLL_HUMAN              Reviewed;         283 AA.
AC   Q8N9W6; Q0JW32; Q53T62; Q969U3;
DE   RecName: Full=Protein boule-like;
GN   Name=BOLL; Synonyms=BOULE;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008494; F:translation activator activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IDA:MGI.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   BOP1_HUMAN              Reviewed;         746 AA.
AC   Q14137; Q969Z6; Q96IS8; Q9BSA7; Q9BVM0;
DE   RecName: Full=Ribosome biogenesis protein BOP1;
DE   AltName: Full=Block of proliferation 1 protein;
GN   Name=BOP1; Synonyms=KIAA0124;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-HAMAP.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; NAS:UniProtKB.
//
ID   BOP_HUMAN               Reviewed;         364 AA.
AC   Q7L3V2; A8K5E7; D3DX21; Q6MZM8; Q6N000; Q9H7A0;
DE   RecName: Full=Protein Bop;
DE   AltName: Full=BH3-only protein;
GN   Name=BOP; Synonyms=C22orf29;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IMP:UniProtKB.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IMP:UniProtKB.
//
ID   BORA_HUMAN              Reviewed;         559 AA.
AC   Q6PGQ7; Q5W0P3; Q5W0P4; Q86YC6; Q96IW9; Q9H640;
DE   RecName: Full=Protein aurora borealis;
DE            Short=HsBora;
GN   Name=BORA; Synonyms=C13orf34;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007088; P:regulation of mitosis; IMP:UniProtKB.
DR   GO; GO:0060236; P:regulation of mitotic spindle organization; IMP:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
//
ID   BOREA_HUMAN             Reviewed;         280 AA.
AC   Q53HL2; D3DPT4; Q53HN1; Q96AM3; Q9NVW5;
DE   RecName: Full=Borealin;
DE   AltName: Full=Cell division cycle-associated protein 8;
DE   AltName: Full=Dasra-B;
DE            Short=hDasra-B;
DE   AltName: Full=Pluripotent embryonic stem cell-related gene 3 protein;
GN   Name=CDCA8; Synonyms=PESCRG3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000089; P:mitotic metaphase; IMP:UniProtKB.
//
ID   BORG1_HUMAN             Reviewed;         210 AA.
AC   O14613; B2RD85; Q9UNS0;
DE   RecName: Full=Cdc42 effector protein 2;
DE   AltName: Full=Binder of Rho GTPases 1;
GN   Name=CDC42EP2; Synonyms=BORG1, CEP2;
DR   GO; GO:0017049; F:GTP-Rho binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IMP:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; NAS:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; TAS:UniProtKB.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IMP:GOC.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
//
ID   BORG2_HUMAN             Reviewed;         254 AA.
AC   Q9UKI2; B2R8S0; O95353; Q9UQJ0;
DE   RecName: Full=Cdc42 effector protein 3;
DE   AltName: Full=Binder of Rho GTPases 2;
DE   AltName: Full=MSE55-related Cdc42-binding protein;
GN   Name=CDC42EP3; Synonyms=BORG2, CEP3;
DR   GO; GO:0005519; F:cytoskeletal regulatory protein binding; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   BORG4_HUMAN             Reviewed;         356 AA.
AC   Q9H3Q1; O95828; Q96FT3;
DE   RecName: Full=Cdc42 effector protein 4;
DE   AltName: Full=Binder of Rho GTPases 4;
GN   Name=CDC42EP4; Synonyms=BORG4, CEP4;
DR   GO; GO:0017049; F:GTP-Rho binding; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
//
ID   BORG3_HUMAN             Reviewed;         148 AA.
AC   Q6NZY7; B0VJZ2; Q8TB51;
DE   RecName: Full=Cdc42 effector protein 5;
DE   AltName: Full=Binder of Rho GTPases 3;
GN   Name=CDC42EP5; Synonyms=BORG3, CEP5;
DR   GO; GO:0017049; F:GTP-Rho binding; IPI:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
//
ID   BORG5_HUMAN             Reviewed;         391 AA.
AC   Q00587; A8K825; Q96GN1;
DE   RecName: Full=Cdc42 effector protein 1;
DE   AltName: Full=Binder of Rho GTPases 5;
DE   AltName: Full=Serum protein MSE55;
GN   Name=CDC42EP1; Synonyms=BORG5, CEP1, MSE55;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
//
ID   BPEC1_HUMAN             Reviewed;         116 AA.
AC   Q9GZL8; Q0VDG2;
DE   RecName: Full=Putative BPES syndrome breakpoint region protein;
DE   AltName: Full=BPES candidate 1;
GN   Name=BPESC1;
//
ID   BPHL_HUMAN              Reviewed;         291 AA.
AC   Q86WA6; Q00306; Q13855; Q3KP51;
DE   RecName: Full=Valacyclovir hydrolase;
DE            Short=VACVase;
DE            Short=Valacyclovirase;
DE            EC=3.1.-.-;
DE   AltName: Full=Biphenyl hydrolase-like protein;
DE   AltName: Full=Biphenyl hydrolase-related protein;
DE            Short=Bph-rp;
DE   AltName: Full=Breast epithelial mucin-associated antigen;
DE            Short=MCNAA;
DE   Flags: Precursor;
GN   Name=BPHL; Synonyms=MCNAA;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0009636; P:response to toxic substance; TAS:ProtInc.
//
ID   BPIA2_HUMAN             Reviewed;         249 AA.
AC   Q96DR5; Q9BQQ0;
DE   RecName: Full=BPI fold-containing family A member 2;
DE   AltName: Full=Parotid secretory protein;
DE            Short=PSP;
DE   AltName: Full=Short palate, lung and nasal epithelium carcinoma-associated protein 2;
DE   Flags: Precursor;
GN   Name=BPIFA2; Synonyms=C20orf70, SPLUNC2; ORFNames=UNQ510/PRO1025;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:UniProt.
//
ID   BPIA3_HUMAN             Reviewed;         254 AA.
AC   Q9BQP9; Q5JWG8; Q6NZ38;
DE   RecName: Full=BPI fold-containing family A member 3;
DE   AltName: Full=Short palate, lung and nasal epithelium carcinoma-associated protein 3;
DE   Flags: Precursor;
GN   Name=BPIFA3; Synonyms=C20orf71, SPLUNC3;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
//
ID   BPIA1_HUMAN             Reviewed;         256 AA.
AC   Q9NP55; A8K9R3; E1P5M9; Q9NZT0;
DE   RecName: Full=BPI fold-containing family A member 1;
DE   AltName: Full=Lung-specific protein X;
DE   AltName: Full=Nasopharyngeal carcinoma-related protein;
DE   AltName: Full=Palate lung and nasal epithelium clone protein;
DE   AltName: Full=Secretory protein in upper respiratory tracts;
DE   AltName: Full=Short PLUNC1;
DE            Short=SPLUNC1;
DE   AltName: Full=Tracheal epithelium-enriched protein;
DE   AltName: Full=Von Ebner protein Hl;
DE   Flags: Precursor;
GN   Name=BPIFA1; Synonyms=LUNX, NASG, PLUNC, SPLUNC1, SPURT;
GN   ORFNames=UNQ787/PRO1606;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IDA:UniProtKB.
DR   GO; GO:1900229; P:negative regulation of single-species biofilm formation in or on host organism; IMP:UniProtKB.
DR   GO; GO:0050828; P:regulation of liquid surface tension; IDA:UniProtKB.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; IDA:UniProtKB.
//
ID   BPIB1_HUMAN             Reviewed;         484 AA.
AC   Q8TDL5; A8K2H8; Q5QP43; Q6UWY1; Q6ZRU7; Q96HK6; Q9BQP8; Q9BWZ6;
AC   Q9H4V6;
DE   RecName: Full=BPI fold-containing family B member 1;
DE   AltName: Full=Long palate, lung and nasal epithelium carcinoma-associated protein 1;
DE   AltName: Full=Von Ebner minor salivary gland protein;
DE            Short=VEMSGP;
DE   Flags: Precursor;
GN   Name=BPIFB1; Synonyms=C20orf114, LPLUNC1; ORFNames=UNQ706/PRO1357;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IDA:UniProt.
//
ID   BPIB2_HUMAN             Reviewed;         458 AA.
AC   Q8N4F0; Q6UWN3; Q6ZME0; Q8NFQ7;
DE   RecName: Full=BPI fold-containing family B member 2;
DE   AltName: Full=Bactericidal/permeability-increasing protein-like 1;
DE            Short=BPI-like 1;
DE   AltName: Full=Long palate, lung and nasal epithelium carcinoma-associated protein 2;
DE   AltName: Full=RYSR;
DE   Flags: Precursor;
GN   Name=BPIFB2; Synonyms=BPIL1, C20orf184, LPLUNC2;
GN   ORFNames=UNQ2489/PRO5776;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
//
ID   BPIB3_HUMAN             Reviewed;         476 AA.
AC   P59826; Q5TDX7;
DE   RecName: Full=BPI fold-containing family B member 3;
DE   AltName: Full=Ligand-binding protein RYA3;
DE   AltName: Full=Long palate, lung and nasal epithelium carcinoma-associated protein 3;
DE   Flags: Precursor;
GN   Name=BPIFB3; Synonyms=C20orf185, LPLUNC3;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
//
ID   BPIB4_HUMAN             Reviewed;         614 AA.
AC   P59827; Q5TDX6;
DE   RecName: Full=BPI fold-containing family B member 4;
DE   AltName: Full=Ligand-binding protein RY2G5;
DE   AltName: Full=Long palate, lung and nasal epithelium carcinoma-associated protein 4;
DE   Flags: Precursor;
GN   Name=BPIFB4; Synonyms=C20orf186, LPLUNC4;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
//
ID   BPIB6_HUMAN             Reviewed;         453 AA.
AC   Q8NFQ5;
DE   RecName: Full=BPI fold-containing family B member 6;
DE   AltName: Full=Bactericidal/permeability-increasing protein-like 3;
DE   Flags: Precursor;
GN   Name=BPIFB6; Synonyms=BPIL3;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
//
ID   BPIFC_HUMAN             Reviewed;         507 AA.
AC   Q8NFQ6;
DE   RecName: Full=BPI fold-containing family C protein;
DE   AltName: Full=Bactericidal/permeability-increasing protein-like 2;
DE            Short=BPI-like 2;
DE   Flags: Precursor;
GN   Name=BPIFC; Synonyms=BPIL2;
DR   GO; GO:0001530; F:lipopolysaccharide binding; NAS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; NAS:UniProtKB.
//
ID   BPI_HUMAN               Reviewed;         487 AA.
AC   P17213; B2RCY2; Q1ZZU8; Q5JRW0; Q8IW58; Q9BYZ9; Q9H1L2; Q9H1M8;
AC   Q9H203; Q9UCT4; Q9UD65;
DE   RecName: Full=Bactericidal permeability-increasing protein;
DE            Short=BPI;
DE   AltName: Full=CAP 57;
DE   Flags: Precursor;
GN   Name=BPI;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:BHF-UCL.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0032717; P:negative regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0043031; P:negative regulation of macrophage activation; IDA:BHF-UCL.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
//
ID   BPL1_HUMAN              Reviewed;         726 AA.
AC   P50747; D3DSG6; Q99451;
DE   RecName: Full=Biotin--protein ligase;
DE            EC=6.3.4.-;
DE   AltName: Full=Biotin apo-protein ligase;
DE   Includes:
DE     RecName: Full=Biotin--[methylmalonyl-CoA-carboxytransferase] ligase;
DE              EC=6.3.4.9;
DE   Includes:
DE     RecName: Full=Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase;
DE              EC=6.3.4.10;
DE     AltName: Full=Holocarboxylase synthetase;
DE              Short=HCS;
DE   Includes:
DE     RecName: Full=Biotin--[methylcrotonoyl-CoA-carboxylase] ligase;
DE              EC=6.3.4.11;
DE   Includes:
DE     RecName: Full=Biotin--[acetyl-CoA-carboxylase] ligase;
DE              EC=6.3.4.15;
GN   Name=HLCS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0009374; F:biotin binding; IDA:UniProtKB.
DR   GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004078; F:biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004079; F:biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004080; F:biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity; IDA:UniProtKB.
DR   GO; GO:0018271; F:biotin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0071110; P:histone biotinylation; IDA:UniProtKB.
DR   GO; GO:0016570; P:histone modification; IDA:UniProtKB.
DR   GO; GO:0009305; P:protein biotinylation; IDA:UniProtKB.
DR   GO; GO:0070781; P:response to biotin; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   BPNT1_HUMAN             Reviewed;         308 AA.
AC   O95861; A8K7C8; B4DPS5; B4DUS9; D3DTA9; Q8WVL5; Q9UGJ3;
DE   RecName: Full=3'(2'),5'-bisphosphate nucleotidase 1;
DE            EC=3.1.3.7;
DE   AltName: Full=Bisphosphate 3'-nucleotidase 1;
DE   AltName: Full=PAP-inositol 1,4-phosphatase;
DE            Short=PIP;
GN   Name=BPNT1;
DR   GO; GO:0008441; F:3'(2'),5'-bisphosphate nucleotidase activity; IEA:Ensembl.
DR   GO; GO:0004441; F:inositol-1,4-bisphosphate 1-phosphatase activity; IEA:Ensembl.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   BPTF_HUMAN              Reviewed;        3046 AA.
AC   Q12830; Q6NX67; Q7Z7D6; Q9UIG2;
DE   RecName: Full=Nucleosome-remodeling factor subunit BPTF;
DE   AltName: Full=Bromodomain and PHD finger-containing transcription factor;
DE   AltName: Full=Fetal Alz-50 clone 1 protein;
DE   AltName: Full=Fetal Alzheimer antigen;
GN   Name=BPTF; Synonyms=FAC1, FALZ;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:HGNC.
DR   GO; GO:0008134; F:transcription factor binding; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007420; P:brain development; IMP:HGNC.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:HGNC.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IMP:HGNC.
//
ID   BRAC_HUMAN              Reviewed;         435 AA.
AC   O15178; E7ERD6; Q4KMP4;
DE   RecName: Full=Brachyury protein;
DE   AltName: Full=Protein T;
GN   Name=T;
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; TAS:ProtInc.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0061371; P:determination of heart left/right asymmetry; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0007509; P:mesoderm migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0001839; P:neural plate morphogenesis; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0014028; P:notochord formation; IEA:Ensembl.
DR   GO; GO:0007341; P:penetration of zona pellucida; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0003257; P:positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; NAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   BRAF_HUMAN              Reviewed;         766 AA.
AC   P15056; A4D1T4; B6HY61; B6HY62; B6HY63; B6HY64; B6HY65; B6HY66;
AC   Q13878; Q3MIN6; Q9UDP8; Q9Y6T3;
DE   RecName: Full=Serine/threonine-protein kinase B-raf;
DE            EC=2.7.11.1;
DE   AltName: Full=Proto-oncogene B-Raf;
DE   AltName: Full=p94;
DE   AltName: Full=v-Raf murine sarcoma viral oncogene homolog B1;
GN   Name=BRAF; Synonyms=BRAF1, RAFB1;
DR   GuidetoPHARMACOLOGY; 1943; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0070849; P:response to epidermal growth factor; IDA:BHF-UCL.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   BRAP_HUMAN              Reviewed;         592 AA.
AC   Q7Z569; B9EGS8; O43238; O75341;
DE   RecName: Full=BRCA1-associated protein;
DE            EC=6.3.2.-;
DE   AltName: Full=BRAP2;
DE   AltName: Full=Impedes mitogenic signal propagation;
DE            Short=IMP;
DE   AltName: Full=RING finger protein 52;
DE   AltName: Full=Renal carcinoma antigen NY-REN-63;
GN   Name=BRAP; Synonyms=RNF52;
DR   GO; GO:0008139; F:nuclear localization sequence binding; IDA:MGI.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000165; P:MAPK cascade; IDA:MGI.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:FlyBase.
DR   GO; GO:0007265; P:Ras protein signal transduction; IDA:MGI.
//
ID   BRAT1_HUMAN             Reviewed;         821 AA.
AC   Q6PJG6; A4D200; C9JY24; Q8IW85; Q8IZ43; Q8WVR8; Q96IV9; Q9H7J8;
AC   Q9UFA3;
DE   RecName: Full=BRCA1-associated ATM activator 1;
DE   AltName: Full=BRCA1-associated protein required for ATM activation protein 1;
GN   Name=BRAT1; Synonyms=BAAT1, C7orf27;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
//
ID   BRCA1_HUMAN             Reviewed;        1863 AA.
AC   P38398; O15129; Q3LRJ0; Q3LRJ6; Q6IN79; Q7KYU9;
DE   RecName: Full=Breast cancer type 1 susceptibility protein;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 53;
GN   Name=BRCA1; Synonyms=RNF53;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:MGI.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0015631; F:tubulin binding; NAS:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; TAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:HGNC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:MGI.
DR   GO; GO:0046600; P:negative regulation of centriole replication; NAS:UniProtKB.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0051573; P:negative regulation of histone H3-K9 methylation; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IDA:BHF-UCL.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IDA:BHF-UCL.
DR   GO; GO:2000617; P:positive regulation of histone H3-K9 acetylation; IDA:BHF-UCL.
DR   GO; GO:2000620; P:positive regulation of histone H4-K16 acetylation; IDA:BHF-UCL.
DR   GO; GO:0070512; P:positive regulation of histone H4-K20 methylation; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006301; P:postreplication repair; IDA:HGNC.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:HGNC.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; IDA:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
//
ID   BRCA2_HUMAN             Reviewed;        3418 AA.
AC   P51587; O00183; O15008; Q13879; Q5TBJ7;
DE   RecName: Full=Breast cancer type 2 susceptibility protein;
DE   AltName: Full=Fanconi anemia group D1 protein;
GN   Name=BRCA2; Synonyms=FACD, FANCD1;
DR   GO; GO:0043015; F:gamma-tubulin binding; IPI:UniProtKB.
DR   GO; GO:0010484; F:H3 histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0010485; F:H4 histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IEA:Ensembl.
DR   GO; GO:0048478; P:replication fork protection; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0010225; P:response to UV-C; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   BRCC3_HUMAN             Reviewed;         316 AA.
AC   P46736; A6QRF8; A6QRF9; A8MUX5; A8MWH0; A9Z1Y0; A9Z1Y5; B1B062;
AC   B4DQN7; Q16107; Q53YX5; Q9BTZ6;
DE   RecName: Full=Lys-63-specific deubiquitinase BRCC36;
DE            EC=3.4.19.-;
DE   AltName: Full=BRCA1-A complex subunit BRCC36;
DE   AltName: Full=BRCA1/BRCA2-containing complex subunit 3;
DE   AltName: Full=BRCA1/BRCA2-containing complex subunit 36;
DE   AltName: Full=BRISC complex subunit BRCC36;
GN   Name=BRCC3; Synonyms=BRCC36, C6.1A, CXorf53;
DR   GO; GO:0030234; F:enzyme regulator activity; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0070537; P:histone H2A K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0010165; P:response to X-ray; IDA:MGI.
//
ID   BRD1_HUMAN              Reviewed;        1058 AA.
AC   O95696; A6ZJA4;
DE   RecName: Full=Bromodomain-containing protein 1;
DE   AltName: Full=BR140-like protein;
DE   AltName: Full=Bromodomain and PHD finger-containing protein 2;
GN   Name=BRD1; Synonyms=BRL, BRPF2;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
//
ID   BRD2_HUMAN              Reviewed;         801 AA.
AC   P25440; A2AAU0; B0S7P0; B1AZT1; O00699; O00700; Q15310; Q5STC9;
AC   Q6P3U2; Q969U4;
DE   RecName: Full=Bromodomain-containing protein 2;
DE   AltName: Full=O27.1.1;
DE   AltName: Full=Really interesting new gene 3 protein;
GN   Name=BRD2; Synonyms=KIAA9001, RING3;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IMP:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRD3_HUMAN              Reviewed;         726 AA.
AC   Q15059; B1APD9; Q4G5Y3; Q5T1R7; Q8N5M3; Q92645;
DE   RecName: Full=Bromodomain-containing protein 3;
DE   AltName: Full=RING3-like protein;
GN   Name=BRD3; Synonyms=KIAA0043, RING3L;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRD4_HUMAN              Reviewed;        1362 AA.
AC   O60885; O60433; Q4G0X8; Q86YS8; Q96PD3;
DE   RecName: Full=Bromodomain-containing protein 4;
DE   AltName: Full=Protein HUNK1;
GN   Name=BRD4; Synonyms=HUNK1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:Ensembl.
DR   GO; GO:0044154; P:histone H3-K14 acetylation; IEA:Ensembl.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IEA:Ensembl.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:2000002; P:negative regulation of DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:MGI.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:1901407; P:regulation of phosphorylation of RNA polymerase II C-terminal domain; IDA:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BRD7_HUMAN              Reviewed;         651 AA.
AC   Q9NPI1; Q4VC09; Q8N2L9; Q96KA4; Q9BV48; Q9UH59;
DE   RecName: Full=Bromodomain-containing protein 7;
DE   AltName: Full=75 kDa bromodomain protein;
DE   AltName: Full=Protein CELTIX-1;
GN   Name=BRD7; Synonyms=BP75, CELTIX1;
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:MGI.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:MGI.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   BRD8_HUMAN              Reviewed;        1235 AA.
AC   Q9H0E9; O43178; Q15355; Q58AB0; Q59GN0; Q969M9;
DE   RecName: Full=Bromodomain-containing protein 8;
DE   AltName: Full=Skeletal muscle abundant protein;
DE   AltName: Full=Skeletal muscle abundant protein 2;
DE   AltName: Full=Thyroid hormone receptor coactivating protein of 120 kDa;
DE            Short=TrCP120;
DE   AltName: Full=p120;
GN   Name=BRD8; Synonyms=SMAP, SMAP2;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   BRD9_HUMAN              Reviewed;         597 AA.
AC   Q9H8M2; A6NFY8; B4DMQ2; B4DR93; Q2XUS1; Q6UWU9; Q8IUS4; Q9H5Q5;
AC   Q9H7R9;
DE   RecName: Full=Bromodomain-containing protein 9;
DE   AltName: Full=Rhabdomyosarcoma antigen MU-RMS-40.8;
GN   Name=BRD9; ORFNames=UNQ3040/PRO9856;
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRDT_HUMAN              Reviewed;         947 AA.
AC   Q58F21; A6NF68; B7Z811; B7Z890; B7ZAX7; D3DT32; O14789; Q05DQ4;
AC   Q6P5T1; Q7Z4A6; Q8IWI6;
DE   RecName: Full=Bromodomain testis-specific protein;
DE   AltName: Full=Cancer/testis antigen 9;
DE            Short=CT9;
DE   AltName: Full=RING3-like protein;
GN   Name=BRDT;
DR   GO; GO:0070577; F:lysine-acetylated histone binding; ISS:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006338; P:chromatin remodeling; ISS:UniProtKB.
DR   GO; GO:0001207; P:histone displacement; ISS:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0007141; P:male meiosis I; ISS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051039; P:positive regulation of transcription during meiosis; ISS:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRE1A_HUMAN             Reviewed;         975 AA.
AC   Q5VTR2; A7MCT5; Q2TB34; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7;
AC   Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83;
DE   RecName: Full=E3 ubiquitin-protein ligase BRE1A;
DE            Short=BRE1-A;
DE            Short=hBRE1;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 20;
GN   Name=RNF20; Synonyms=BRE1A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0031062; P:positive regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   BRE1B_HUMAN             Reviewed;        1001 AA.
AC   O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82;
DE   RecName: Full=E3 ubiquitin-protein ligase BRE1B;
DE            Short=BRE1-B;
DE            EC=6.3.2.-;
DE   AltName: Full=95 kDa retinoblastoma-associated protein;
DE            Short=RBP95;
DE   AltName: Full=RING finger protein 40;
GN   Name=RNF40; Synonyms=BRE1B, KIAA0661;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   BRE_HUMAN               Reviewed;         383 AA.
AC   Q9NXR7; A8K4X1; D6W562; D6W563; Q13880; Q4ZFX8; Q53SD0; Q969X9;
AC   Q96P06;
DE   RecName: Full=BRCA1-A complex subunit BRE;
DE   AltName: Full=BRCA1/BRCA2-containing complex subunit 45;
DE   AltName: Full=Brain and reproductive organ-expressed protein;
GN   Name=BRE; Synonyms=BRCC45;
DR   GO; GO:0000268; F:peroxisome targeting sequence binding; TAS:UniProtKB.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   BRF2_HUMAN              Reviewed;         419 AA.
AC   Q9HAW0; B2RD62; D3DSW6; Q9H2Y3; Q9H3B3; Q9NUY6;
DE   RecName: Full=Transcription factor IIIB 50 kDa subunit;
DE            Short=TFIIIB50;
DE            Short=hTFIIIB50;
DE   AltName: Full=B-related factor 2;
DE            Short=BRF-2;
DE   AltName: Full=hBRFU;
GN   Name=BRF2; Synonyms=BRFU; ORFNames=PRO1470;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   BRI3B_HUMAN             Reviewed;         251 AA.
AC   Q8WY22; Q8WY23;
DE   RecName: Full=BRI3-binding protein;
DE            Short=I3-binding protein;
DE   AltName: Full=Cervical cancer 1 proto-oncogene-binding protein KG19;
DE   AltName: Full=HCCRBP-1;
GN   Name=BRI3BP; Synonyms=KG19;
//
ID   BRID5_HUMAN             Reviewed;         260 AA.
AC   Q6PL45; C9J7K2; Q8IXU9;
DE   RecName: Full=BRICHOS domain-containing protein 5;
GN   Name=BRICD5; Synonyms=C16orf79;
//
ID   BRI3_HUMAN              Reviewed;         125 AA.
AC   O95415; D6W5R8; Q8WV52; Q9UIC6;
DE   RecName: Full=Brain protein I3;
DE   AltName: Full=pRGR2;
GN   Name=BRI3;
DR   GO; GO:0042802; F:identical protein binding; IPI:MGI.
//
ID   BRIT2_HUMAN             Reviewed;         145 AA.
AC   P59051; A1L3W1; D3DSH8;
DE   RecName: Full=Putative uncharacterized protein encoded by BRWD1-IT2;
DE   AltName: Full=BRWD1 intronic transcript 2;
GN   Name=BRWD1-IT2; Synonyms=C21orf87, NCRNA00257;
//
ID   BRK1_HUMAN              Reviewed;          75 AA.
AC   Q8WUW1; B2R5E2; Q9P082;
DE   RecName: Full=Protein BRICK1;
DE            Short=BRK1;
GN   Name=BRK1; Synonyms=C3orf10; ORFNames=HSPC300, MDS027;
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0048870; P:cell motility; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IDA:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IMP:UniProt.
DR   GO; GO:0070207; P:protein homotrimerization; IDA:UniProt.
DR   GO; GO:0016601; P:Rac protein signal transduction; IDA:UniProt.
//
ID   BRM1L_HUMAN             Reviewed;         323 AA.
AC   Q5PSV4; A6NFW5; A6NH45; Q9BRI4;
DE   RecName: Full=Breast cancer metastasis-suppressor 1-like protein;
DE   AltName: Full=BRMS1-homolog protein p40;
DE   AltName: Full=BRMS1-like protein p40;
GN   Name=BRMS1L;
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRMS1_HUMAN             Reviewed;         246 AA.
AC   Q9HCU9; Q6IAI2;
DE   RecName: Full=Breast cancer metastasis-suppressor 1;
GN   Name=BRMS1;
DR   GO; GO:0051059; F:NF-kappaB binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:2000210; P:positive regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0090312; P:positive regulation of protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRNP1_HUMAN             Reviewed;         761 AA.
AC   O60477; Q6IPV6; Q6P1A0; Q8WU22;
DE   RecName: Full=BMP/retinoic acid-inducible neural-specific protein 1;
DE   AltName: Full=Deleted in bladder cancer protein 1;
DE   Flags: Precursor;
GN   Name=BRINP1; Synonyms=DBC1, DBCCR1, FAM5A; ORFNames=IB3089A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
//
ID   BRNP2_HUMAN             Reviewed;         783 AA.
AC   Q9C0B6; O95560; Q6ZWC1; Q7LCZ9; Q8N360;
DE   RecName: Full=BMP/retinoic acid-inducible neural-specific protein 2;
DE   AltName: Full=DBCCR1-like protein 2;
DE   Flags: Precursor;
GN   Name=BRINP2; Synonyms=DBCCR1L2, FAM5B, KIAA1747;
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
//
ID   BRNP3_HUMAN             Reviewed;         766 AA.
AC   Q76B58; B3KVP1; O95726; Q2M330;
DE   RecName: Full=BMP/retinoic acid-inducible neural-specific protein 3;
DE   AltName: Full=DBCCR1-like protein 1;
DE   Flags: Precursor;
GN   Name=BRINP3; Synonyms=DBCCR1L, DBCCR1L1, FAM5C;
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
//
ID   BROMI_HUMAN             Reviewed;        1257 AA.
AC   Q96NH3; Q5SZD6; Q5SZM6; Q6ZMY4; Q6ZUR7; Q8NB47;
DE   RecName: Full=Protein broad-minded;
DE   AltName: Full=TBC1 domain family member 32;
GN   Name=TBC1D32; Synonyms=BROMI, C6orf170, C6orf171;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   BROX_HUMAN              Reviewed;         411 AA.
AC   Q5VW32; Q96MG1;
DE   RecName: Full=BRO1 domain-containing protein BROX;
DE   AltName: Full=BRO1 domain- and CAAX motif-containing protein;
DE   Flags: Precursor;
GN   Name=BROX; Synonyms=BROFTI, C1orf58;
//
ID   BRPF1_HUMAN             Reviewed;        1214 AA.
AC   P55201; B4DEZ6; Q7Z6E0; Q8TCM6; Q9UHI0;
DE   RecName: Full=Peregrin;
DE   AltName: Full=Bromodomain and PHD finger-containing protein 1;
DE   AltName: Full=Protein Br140;
GN   Name=BRPF1; Synonyms=BR140;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRPF3_HUMAN             Reviewed;        1205 AA.
AC   Q9ULD4; A6NJE2; Q5R3K8;
DE   RecName: Full=Bromodomain and PHD finger-containing protein 3;
GN   Name=BRPF3; Synonyms=KIAA1286;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   BRS3_HUMAN              Reviewed;         399 AA.
AC   P32247;
DE   RecName: Full=Bombesin receptor subtype-3;
DE            Short=BRS-3;
GN   Name=BRS3;
DR   GuidetoPHARMACOLOGY; 40; -.
DR   GO; GO:0004946; F:bombesin receptor activity; TAS:ProtInc.
DR   GO; GO:0008343; P:adult feeding behavior; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
//
ID   BRSK1_HUMAN             Reviewed;         778 AA.
AC   Q8TDC3; F1DG44; Q5J5B5; Q8NDD0; Q8NDR4; Q8TDC2; Q96AV4; Q96JL4;
DE   RecName: Full=Serine/threonine-protein kinase BRSK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Brain-selective kinase 1;
DE            EC=2.7.11.26;
DE   AltName: Full=Brain-specific serine/threonine-protein kinase 1;
DE            Short=BR serine/threonine-protein kinase 1;
DE   AltName: Full=Serine/threonine-protein kinase SAD-B;
DE   AltName: Full=Synapses of Amphids Defective homolog 1;
DE            Short=SAD1 homolog;
DE            Short=hSAD1;
GN   Name=BRSK1; Synonyms=KIAA1811, SAD1, SADB;
DR   GuidetoPHARMACOLOGY; 1946; -.
DR   GO; GO:0005524; F:ATP binding; IC:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; ISS:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
//
ID   BRSK2_HUMAN             Reviewed;         736 AA.
AC   Q8IWQ3; O60843; O95099; Q5J5B4; Q6ZMQ4; Q8TB60;
DE   RecName: Full=Serine/threonine-protein kinase BRSK2;
DE            EC=2.7.11.1;
DE   AltName: Full=Brain-selective kinase 2;
DE            EC=2.7.11.26;
DE   AltName: Full=Brain-specific serine/threonine-protein kinase 2;
DE            Short=BR serine/threonine-protein kinase 2;
DE   AltName: Full=Serine/threonine-protein kinase 29;
DE   AltName: Full=Serine/threonine-protein kinase SAD-A;
GN   Name=BRSK2; Synonyms=C11orf7, PEN11B, SADA, STK29; ORFNames=HUSSY-12;
DR   GuidetoPHARMACOLOGY; 1947; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.
//
ID   BRWD1_HUMAN             Reviewed;        2320 AA.
AC   Q9NSI6; C9JK25; O43721; Q5R2V0; Q5R2V1; Q6P2D1; Q8TCV3; Q96QG9;
AC   Q96QH0; Q9NUK1;
DE   RecName: Full=Bromodomain and WD repeat-containing protein 1;
DE   AltName: Full=WD repeat-containing protein 9;
GN   Name=BRWD1; Synonyms=C21orf107, WDR9;
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BRWD3_HUMAN             Reviewed;        1802 AA.
AC   Q6RI45; C9IZ39; C9J3F3; Q2T9J6; Q5JRN1; Q6RI37; Q6RI42; Q6RI44;
AC   Q8N916;
DE   RecName: Full=Bromodomain and WD repeat-containing protein 3;
GN   Name=BRWD3;
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   BRX1_HUMAN              Reviewed;         353 AA.
AC   Q8TDN6; A8K0P5; Q3ZTT4; Q8N453; Q96DH1;
DE   RecName: Full=Ribosome biogenesis protein BRX1 homolog;
DE   AltName: Full=Brix domain-containing protein 2;
GN   Name=BRIX1; Synonyms=BRIX, BXDC2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   BSCL2_HUMAN             Reviewed;         398 AA.
AC   Q96G97; G3XAE4; Q567S1; Q96SV1; Q9BSQ0;
DE   RecName: Full=Seipin;
DE   AltName: Full=Bernardinelli-Seip congenital lipodystrophy type 2 protein;
GN   Name=BSCL2;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0034389; P:lipid particle organization; IMP:UniProtKB.
DR   GO; GO:0019915; P:lipid storage; IMP:UniProtKB.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.
//
ID   BSDC1_HUMAN             Reviewed;         430 AA.
AC   Q9NW68; B4DMS7; B4DTI7; B4DTP7; B4E2X8; Q49AT8; Q68DY6; Q6IAA3;
AC   Q6MZK1; Q6UXS1; Q9HAL9;
DE   RecName: Full=BSD domain-containing protein 1;
GN   Name=BSDC1; ORFNames=UNQ2494/PRO5781;
//
ID   BSH_HUMAN               Reviewed;         233 AA.
AC   Q3C1V8;
DE   RecName: Full=Brain-specific homeobox protein homolog;
GN   Name=BSX; Synonyms=BSX1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0060056; P:mammary gland involution; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BSND_HUMAN              Reviewed;         320 AA.
AC   Q8WZ55; Q6NT28;
DE   RecName: Full=Barttin;
GN   Name=BSND; Synonyms=BART;
DR   GO; GO:0005254; F:chloride channel activity; IEA:Ensembl.
DR   GO; GO:0017081; F:chloride channel regulator activity; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; ISS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   BSN_HUMAN               Reviewed;        3926 AA.
AC   Q9UPA5; O43161; Q7LGH3;
DE   RecName: Full=Protein bassoon;
DE   AltName: Full=Zinc finger protein 231;
GN   Name=BSN; Synonyms=KIAA0434, ZNF231;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   BSPH1_HUMAN             Reviewed;         132 AA.
AC   Q075Z2; A6NIZ5;
DE   RecName: Full=Binder of sperm protein homolog 1;
DE   AltName: Full=Bovine seminal plasma protein homolog 1;
DE   AltName: Full=Bovine seminal plasma protein-like 1;
DE   Flags: Precursor;
GN   Name=BSPH1;
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
//
ID   BSPRY_HUMAN             Reviewed;         402 AA.
AC   Q5W0U4; B3KS19; Q96DJ2; Q9H4E4; Q9NXN0;
DE   RecName: Full=B box and SPRY domain-containing protein;
GN   Name=BSPRY;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
//
ID   BSSP4_HUMAN             Reviewed;         317 AA.
AC   Q9GZN4; O43342; Q6UXE0;
DE   RecName: Full=Brain-specific serine protease 4;
DE            Short=BSSP-4;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease 22;
DE   AltName: Full=Serine protease 26;
DE   AltName: Full=Tryptase epsilon;
DE   Flags: Precursor;
GN   Name=PRSS22; Synonyms=BSSP4, PRSS26; ORFNames=SP001LA, UNQ302/PRO343;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   BST1_HUMAN              Reviewed;         318 AA.
AC   Q10588; B2R6A2; Q5U0K0; Q96EN3;
DE   RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2;
DE            EC=3.2.2.6;
DE   AltName: Full=ADP-ribosyl cyclase 2;
DE   AltName: Full=Bone marrow stromal antigen 1;
DE            Short=BST-1;
DE   AltName: Full=Cyclic ADP-ribose hydrolase 2;
DE            Short=cADPr hydrolase 2;
DE   AltName: CD_antigen=CD157;
DE   Flags: Precursor;
GN   Name=BST1;
DR   GO; GO:0050135; F:NAD(P)+ nucleosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003953; F:NAD+ nucleosidase activity; IEA:InterPro.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   BST2_HUMAN              Reviewed;         180 AA.
AC   Q10589; A8K4Y4; Q53G07;
DE   RecName: Full=Bone marrow stromal antigen 2;
DE            Short=BST-2;
DE   AltName: Full=HM1.24 antigen;
DE   AltName: Full=Tetherin;
DE   AltName: CD_antigen=CD317;
DE   Flags: Precursor;
GN   Name=BST2;
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:1901253; P:negative regulation of intracellular transport of viral material; IDA:UniProtKB.
DR   GO; GO:0002737; P:negative regulation of plasmacytoid dendritic cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; ISS:UniProtKB.
DR   GO; GO:0035456; P:response to interferon-beta; ISS:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; ISS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   BT1A1_HUMAN             Reviewed;         526 AA.
AC   Q13410; Q4VAN3; Q4VAN4; Q9H458;
DE   RecName: Full=Butyrophilin subfamily 1 member A1;
DE            Short=BT;
DE   Flags: Precursor;
GN   Name=BTN1A1; Synonyms=BTN;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
//
ID   BT2A1_HUMAN             Reviewed;         527 AA.
AC   Q7KYR7; B4DLP9; E9PGR4; O00475; P78408; Q59EN4; Q7KYQ7; Q7Z386;
AC   Q96AV7; Q9NU62;
DE   RecName: Full=Butyrophilin subfamily 2 member A1;
DE   Flags: Precursor;
GN   Name=BTN2A1; Synonyms=BT2.1, BTF1;
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
//
ID   BT2A2_HUMAN             Reviewed;         523 AA.
AC   Q8WVV5; A6NM84; B4DE97; B4DQ01; E9PH07; O00480;
DE   RecName: Full=Butyrophilin subfamily 2 member A2;
DE   Flags: Precursor;
GN   Name=BTN2A2; Synonyms=BT2.2, BTF2;
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0031324; P:negative regulation of cellular metabolic process; ISS:UniProtKB.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.
//
ID   BT2A3_HUMAN             Reviewed;         586 AA.
AC   Q96KV6; A6NEF4;
DE   RecName: Full=Putative butyrophilin subfamily 2 member A3;
DE   Flags: Precursor;
GN   Name=BTN2A3P; Synonyms=BTN2A3;
//
ID   BT3A1_HUMAN             Reviewed;         513 AA.
AC   O00481; A2A278; A8K2C8; B4DIQ1; B4DRM2; E9PGB4; E9PHG8; Q0P515;
AC   Q147X5; Q53F15; Q99420; Q9HCY1;
DE   RecName: Full=Butyrophilin subfamily 3 member A1;
DE   AltName: CD_antigen=CD277;
DE   Flags: Precursor;
GN   Name=BTN3A1; Synonyms=BTF5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050798; P:activated T cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050663; P:cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0072643; P:interferon-gamma secretion; IMP:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
//
ID   BT3A2_HUMAN             Reviewed;         334 AA.
AC   P78410; B4DRT7; B4E103; F5H791; F8W6E0; O00477; O15338; O75658;
AC   Q76PA0; Q9BU81; Q9NR44;
DE   RecName: Full=Butyrophilin subfamily 3 member A2;
DE   Flags: Precursor;
GN   Name=BTN3A2; Synonyms=BT3.2, BTF3, BTF4;
DR   GO; GO:0072643; P:interferon-gamma secretion; IMP:UniProtKB.
DR   GO; GO:0002456; P:T cell mediated immunity; IMP:UniProtKB.
//
ID   BT3A3_HUMAN             Reviewed;         584 AA.
AC   O00478; B4DWI7; E9PCP5;
DE   RecName: Full=Butyrophilin subfamily 3 member A3;
DE   Flags: Precursor;
GN   Name=BTN3A3; Synonyms=BTF3;
DR   GO; GO:0002456; P:T cell mediated immunity; IMP:UniProtKB.
//
ID   BT3L4_HUMAN             Reviewed;         158 AA.
AC   Q96K17; B3KNJ1; D3DQ32; G3V1C6;
DE   RecName: Full=Transcription factor BTF3 homolog 4;
DE   AltName: Full=Basic transcription factor 3-like 4;
GN   Name=BTF3L4;
//
ID   BTAF1_HUMAN             Reviewed;        1849 AA.
AC   O14981; O43578;
DE   RecName: Full=TATA-binding protein-associated factor 172;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase BTAF1;
DE   AltName: Full=B-TFIID transcription factor-associated 170 kDa subunit;
DE   AltName: Full=TAF(II)170;
DE   AltName: Full=TBP-associated factor 172;
DE            Short=TAF-172;
GN   Name=BTAF1; Synonyms=TAF172;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   BTBD1_HUMAN             Reviewed;         482 AA.
AC   Q9H0C5; A6NMI8; Q9BX71; Q9NWN4;
DE   RecName: Full=BTB/POZ domain-containing protein 1;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 8;
DE            Short=HCV NS5A-transactivated protein 8;
GN   Name=BTBD1; Synonyms=C15orf1, NS5ATP8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0043393; P:regulation of protein binding; NAS:UniProtKB.
//
ID   BTBD2_HUMAN             Reviewed;         525 AA.
AC   Q9BX70; O60418; O75248; Q4VBZ1; Q6IAC5; Q7Z5W0; Q96SX8; Q9NPS1;
AC   Q9NX81;
DE   RecName: Full=BTB/POZ domain-containing protein 2;
GN   Name=BTBD2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   BTBD3_HUMAN             Reviewed;         522 AA.
AC   Q9Y2F9; D3DW19; Q5JY73;
DE   RecName: Full=BTB/POZ domain-containing protein 3;
GN   Name=BTBD3; Synonyms=KIAA0952;
DR   GO; GO:0021987; P:cerebral cortex development; ISS:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.
//
ID   BTBD6_HUMAN             Reviewed;         485 AA.
AC   Q96KE9; Q8IVQ7; Q9BR94;
DE   RecName: Full=BTB/POZ domain-containing protein 6;
DE   AltName: Full=Lens BTB domain protein;
GN   Name=BTBD6; Synonyms=BDPL;
//
ID   BTBD7_HUMAN             Reviewed;        1132 AA.
AC   Q9P203; A8K5V7; Q69Z05; Q7Z308; Q86TS0; Q9HAA4; Q9NVM0;
DE   RecName: Full=BTB/POZ domain-containing protein 7;
GN   Name=BTBD7; Synonyms=KIAA1525;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0060693; P:regulation of branching involved in salivary gland morphogenesis; IEA:Ensembl.
//
ID   BTBD8_HUMAN             Reviewed;         378 AA.
AC   Q5XKL5; Q6V9S5;
DE   RecName: Full=BTB/POZ domain-containing protein 8;
GN   Name=BTBD8;
//
ID   BTBD9_HUMAN             Reviewed;         612 AA.
AC   Q96Q07; Q494V9; Q494W1; Q96M00;
DE   RecName: Full=BTB/POZ domain-containing protein 9;
GN   Name=BTBD9; Synonyms=KIAA1880;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0042748; P:circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0060586; P:multicellular organismal iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:1900242; P:regulation of synaptic vesicle endocytosis; IEA:Ensembl.
DR   GO; GO:0050951; P:sensory perception of temperature stimulus; IEA:Ensembl.
DR   GO; GO:0042428; P:serotonin metabolic process; IEA:Ensembl.
//
ID   BTBDA_HUMAN             Reviewed;         475 AA.
AC   Q9BSF8; Q86WG1;
DE   RecName: Full=BTB/POZ domain-containing protein 10;
GN   Name=BTBD10;
//
ID   BTBDB_HUMAN             Reviewed;        1104 AA.
AC   A6QL63; A4FU41; B3KXG3; C9J019; C9JK80; E9PHS4; Q3ZTQ4; Q52M89;
AC   Q6ZV99; Q8N245;
DE   RecName: Full=Ankyrin repeat and BTB/POZ domain-containing protein BTBD11;
DE   AltName: Full=BTB/POZ domain-containing protein 11;
GN   Name=BTBD11;
//
ID   BTBDG_HUMAN             Reviewed;         506 AA.
AC   Q32M84; A6NM63; Q4VXL1; Q96LN0;
DE   RecName: Full=BTB/POZ domain-containing protein 16;
GN   Name=BTBD16; Synonyms=C10orf87;
//
ID   BTBDH_HUMAN             Reviewed;         478 AA.
AC   A6NE02;
DE   RecName: Full=BTB/POZ domain-containing protein 17;
DE   AltName: Full=Galectin-3-binding protein-like;
DE   Flags: Precursor;
GN   Name=BTBD17;
DR   GO; GO:0045071; P:negative regulation of viral genome replication; ISS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; ISS:UniProtKB.
//
ID   BTBDI_HUMAN             Reviewed;         712 AA.
AC   B2RXH4;
DE   RecName: Full=BTB/POZ domain-containing protein 18;
GN   Name=BTBD18;
//
ID   BTBDJ_HUMAN             Reviewed;         291 AA.
AC   C9JJ37; B4E384; B7ZC36; B7ZC37;
DE   RecName: Full=BTB/POZ domain-containing protein 19;
GN   Name=BTBD19;
//
ID   BTC_HUMAN               Reviewed;         178 AA.
AC   P35070; Q96F48;
DE   RecName: Full=Probetacellulin;
DE   Contains:
DE     RecName: Full=Betacellulin;
DE              Short=BTC;
DE   Flags: Precursor;
GN   Name=BTC;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; TAS:ProtInc.
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0035810; P:positive regulation of urine volume; IEA:Ensembl.
//
ID   BTD_HUMAN               Reviewed;         543 AA.
AC   P43251; A6NHF2; B2R865; B4DFX1; B4DLJ9; Q96EM9;
DE   RecName: Full=Biotinidase;
DE            Short=Biotinase;
DE            EC=3.5.1.12;
DE   Flags: Precursor;
GN   Name=BTD;
DR   GO; GO:0004075; F:biotin carboxylase activity; TAS:ProtInc.
DR   GO; GO:0047708; F:biotinidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   BTF3_HUMAN              Reviewed;         206 AA.
AC   P20290; A8K510; Q13893; Q76M56;
DE   RecName: Full=Transcription factor BTF3;
DE   AltName: Full=Nascent polypeptide-associated complex subunit beta;
DE            Short=NAC-beta;
DE   AltName: Full=RNA polymerase B transcription factor 3;
GN   Name=BTF3; Synonyms=NACB; ORFNames=OK/SW-cl.8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   BTG1_HUMAN              Reviewed;         171 AA.
AC   P62324; P31607;
DE   RecName: Full=Protein BTG1;
DE   AltName: Full=B-cell translocation gene 1 protein;
GN   Name=BTG1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   BTG2_HUMAN              Reviewed;         158 AA.
AC   P78543; Q3KR25; Q5VUT0;
DE   RecName: Full=Protein BTG2;
DE   AltName: Full=BTG family member 2;
DE   AltName: Full=NGF-inducible anti-proliferative protein PC3;
GN   Name=BTG2; Synonyms=PC3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:2000178; P:negative regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:MGI.
DR   GO; GO:0006479; P:protein methylation; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   BTG3_HUMAN              Reviewed;         252 AA.
AC   Q14201; D3DSC4; Q53XV1; Q96ET7;
DE   RecName: Full=Protein BTG3;
DE   AltName: Full=Abundant in neuroepithelium area protein;
DE   AltName: Full=BTG family member 3;
DE   AltName: Full=Protein Tob5;
GN   Name=BTG3; Synonyms=ANA, TOB5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:MGI.
//
ID   BTG4_HUMAN              Reviewed;         223 AA.
AC   Q9NY30; Q8NEH7;
DE   RecName: Full=Protein BTG4;
DE   AltName: Full=BTG family member 4;
DE   AltName: Full=Protein PC3b;
GN   Name=BTG4; Synonyms=PC3B;
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; TAS:UniProtKB.
//
ID   BTK_HUMAN               Reviewed;         659 AA.
AC   Q06187; B2RAW1; Q32ML5;
DE   RecName: Full=Tyrosine-protein kinase BTK;
DE            EC=2.7.10.2;
DE   AltName: Full=Agammaglobulinemia tyrosine kinase;
DE            Short=ATK;
DE   AltName: Full=B-cell progenitor kinase;
DE            Short=BPK;
DE   AltName: Full=Bruton tyrosine kinase;
GN   Name=BTK; Synonyms=AGMX1, ATK, BPK;
DR   GuidetoPHARMACOLOGY; 1948; -.
DR   GO; GO:0005524; F:ATP binding; TAS:HGNC.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:HGNC.
DR   GO; GO:0002250; P:adaptive immune response; TAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; TAS:HGNC.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002553; P:histamine secretion by mast cell; IEA:Ensembl.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:HGNC.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:HGNC.
DR   GO; GO:0002902; P:regulation of B cell apoptotic process; TAS:UniProtKB.
DR   GO; GO:0002721; P:regulation of B cell cytokine production; TAS:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0000302; P:response to reactive oxygen species; IEA:Ensembl.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BTLA_HUMAN              Reviewed;         289 AA.
AC   Q7Z6A9; Q3B831; Q3HS85; Q6ZNH9;
DE   RecName: Full=B- and T-lymphocyte attenuator;
DE   AltName: Full=B- and T-lymphocyte-associated protein;
DE   AltName: CD_antigen=CD272;
DE   Flags: Precursor;
GN   Name=BTLA;
DR   GO; GO:0004872; F:receptor activity; IEA:Ensembl.
DR   GO; GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   BTNL2_HUMAN             Reviewed;         455 AA.
AC   Q9UIR0; A0PJV5; B0UYW9; B0V0N6; O98261; Q08E96; Q58R22; Q58R23;
AC   Q5JYF9; Q5MP42; Q5MP43; Q5RIF8; Q5SP08; Q5SP09; Q5SRW3; Q5SRW4;
AC   Q5SU36; Q95HK0;
DE   RecName: Full=Butyrophilin-like protein 2;
DE            Short=BTL-II;
GN   Name=BTNL2;
//
ID   BTNL3_HUMAN             Reviewed;         466 AA.
AC   Q6UXE8; Q496L7; Q9Y2C7;
DE   RecName: Full=Butyrophilin-like protein 3;
DE   AltName: Full=Butyrophilin-like receptor;
DE   Flags: Precursor;
GN   Name=BTNL3; Synonyms=BTNLR, COLF4100; ORFNames=UNQ744/PRO1472;
//
ID   BTNL9_HUMAN             Reviewed;         535 AA.
AC   Q6UXG8; A6NL42; Q6P660; Q96DM5;
DE   RecName: Full=Butyrophilin-like protein 9;
DE   Flags: Precursor;
GN   Name=BTNL9; ORFNames=UNQ1900/PRO4346;
//
ID   BTNL8_HUMAN             Reviewed;         500 AA.
AC   Q6UX41; A4QMZ8; A6NEX6; B7Z409; B7Z5B1; E9PEF6; E9PG07; F2Z2B2;
AC   F8W712; Q9H730;
DE   RecName: Full=Butyrophilin-like protein 8;
DE   Flags: Precursor;
GN   Name=BTNL8; ORFNames=UNQ702/PRO1347;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   BTNLA_HUMAN             Reviewed;         291 AA.
AC   A8MVZ5;
DE   RecName: Full=Butyrophilin-like protein 10;
DE   Flags: Precursor;
GN   Name=BTNL10;
//
ID   BUB1B_HUMAN             Reviewed;        1050 AA.
AC   O60566; B2R6U0; B4DL09; B4DLG3; O60501; O60627; O60758; O75389;
AC   Q59HH6; Q8WV50; Q96KM4;
DE   RecName: Full=Mitotic checkpoint serine/threonine-protein kinase BUB1 beta;
DE            EC=2.7.11.1;
DE   AltName: Full=MAD3/BUB1-related protein kinase;
DE            Short=hBUBR1;
DE   AltName: Full=Mitotic checkpoint kinase MAD3L;
DE   AltName: Full=Protein SSK1;
GN   Name=BUB1B; Synonyms=BUBR1, MAD3L, SSK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0071459; P:protein localization to chromosome, centromeric region; IEA:Ensembl.
DR   GO; GO:0034501; P:protein localization to kinetochore; IPI:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007051; P:spindle organization; NAS:UniProtKB.
//
ID   BUB1_HUMAN              Reviewed;        1085 AA.
AC   O43683; E9PC26; F5GXI5; O43430; O43643; O60626; Q53QE4;
DE   RecName: Full=Mitotic checkpoint serine/threonine-protein kinase BUB1;
DE            Short=hBUB1;
DE            EC=2.7.11.1;
DE   AltName: Full=BUB1A;
GN   Name=BUB1; Synonyms=BUB1L;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:ProtInc.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0051983; P:regulation of chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0007063; P:regulation of sister chromatid cohesion; IDA:UniProtKB.
DR   GO; GO:0071173; P:spindle assembly checkpoint; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   BUB3_HUMAN              Reviewed;         328 AA.
AC   O43684; A6NJ42; B2R6E7; D3DRE9; O43685;
DE   RecName: Full=Mitotic checkpoint protein BUB3;
GN   Name=BUB3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IDA:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:Ensembl.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051983; P:regulation of chromosome segregation; IEA:Ensembl.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071173; P:spindle assembly checkpoint; IDA:UniProtKB.
//
ID   BUD13_HUMAN             Reviewed;         619 AA.
AC   Q9BRD0; A8K0S0; Q96LS7;
DE   RecName: Full=BUD13 homolog;
GN   Name=BUD13;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006406; P:mRNA export from nucleus; ISS:BHF-UCL.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:BHF-UCL.
//
ID   BUD31_HUMAN             Reviewed;         144 AA.
AC   P41223; A4D274; D6W5S6; Q6IB53; Q9UDV1;
DE   RecName: Full=Protein BUD31 homolog;
DE   AltName: Full=Protein EDG-2;
DE   AltName: Full=Protein G10 homolog;
GN   Name=BUD31; Synonyms=EDG2;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   BUP1_HUMAN              Reviewed;         384 AA.
AC   Q9UBR1; A3KMF8; Q9UIR3;
DE   RecName: Full=Beta-ureidopropionase;
DE            EC=3.5.1.6;
DE   AltName: Full=BUP-1;
DE   AltName: Full=Beta-alanine synthase;
DE   AltName: Full=N-carbamoyl-beta-alanine amidohydrolase;
GN   Name=UPB1; Synonyms=BUP1;
DR   GO; GO:0003837; F:beta-ureidopropionase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019483; P:beta-alanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   BVAS1_HUMAN             Reviewed;          98 AA.
AC   Q5T3Y7; Q5T552;
DE   RecName: Full=Putative uncharacterized protein BVES-AS1;
DE   AltName: Full=BVES antisense RNA 1;
DE   AltName: Full=BVES antisense gene protein 1;
GN   Name=BVES-AS1; Synonyms=C6orf112;
//
ID   BWR1B_HUMAN             Reviewed;         253 AA.
AC   Q8N1D0; E9PLK8; O43563;
DE   RecName: Full=Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein;
DE   AltName: Full=Organic cation transporter-like protein 2 antisense protein;
DE   AltName: Full=Solute carrier family 22 member 1-like antisense protein;
DE   AltName: Full=Solute carrier family 22 member 18 antisense protein;
DE   AltName: Full=p27-Beckwith-Wiedemann region 1 B;
DE            Short=p27-BWR1B;
GN   Name=SLC22A18AS; Synonyms=BWR1B, BWSCR1B, ORCTL2S, SLC22A1LS;
//
ID   BY55_HUMAN              Reviewed;         181 AA.
AC   O95971;
DE   RecName: Full=CD160 antigen;
DE   AltName: Full=Natural killer cell receptor BY55;
DE   AltName: CD_antigen=CD160;
DE   Flags: Precursor;
GN   Name=CD160; Synonyms=BY55;
DR   GO; GO:0032393; F:MHC class I receptor activity; IDA:HGNC.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; IDA:HGNC.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   BYST_HUMAN              Reviewed;         437 AA.
AC   Q13895; Q6P5W4; Q86W44; Q96IP8;
DE   RecName: Full=Bystin;
GN   Name=BYSL;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:Ensembl.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   BZW1_HUMAN              Reviewed;         419 AA.
AC   Q7L1Q6; B4DLZ8; B4DWF7; Q14281; Q15394; Q9BUY0;
DE   RecName: Full=Basic leucine zipper and W2 domain-containing protein 1;
DE   AltName: Full=Protein Orf;
GN   Name=BZW1; Synonyms=BZAP45, KIAA0005;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   BZW2_HUMAN              Reviewed;         419 AA.
AC   Q9Y6E2; A4D123; Q3B779; Q9H3F7;
DE   RecName: Full=Basic leucine zipper and W2 domain-containing protein 2;
GN   Name=BZW2; ORFNames=HSPC028, MSTP017;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   C102A_HUMAN             Reviewed;         550 AA.
AC   Q96A19; Q9BT74;
DE   RecName: Full=Coiled-coil domain-containing protein 102A;
GN   Name=CCDC102A;
//
ID   C102B_HUMAN             Reviewed;         513 AA.
AC   Q68D86; Q7Z467; Q8NDK7; Q9H5C1;
DE   RecName: Full=Coiled-coil domain-containing protein 102B;
GN   Name=CCDC102B; Synonyms=C18orf14;
//
ID   C10_HUMAN               Reviewed;         126 AA.
AC   Q99622; B2R4Q6;
DE   RecName: Full=Protein C10;
GN   Name=C12orf57; Synonyms=C10;
//
ID   C11B1_HUMAN             Reviewed;         503 AA.
AC   P15538; Q14095; Q4VAQ8; Q4VAQ9; Q9UML2;
DE   RecName: Full=Cytochrome P450 11B1, mitochondrial;
DE   AltName: Full=CYPXIB1;
DE   AltName: Full=Cytochrome P-450c11;
DE            Short=Cytochrome P450C11;
DE   AltName: Full=Steroid 11-beta-hydroxylase;
DE            EC=1.14.15.4;
DE   Flags: Precursor;
GN   Name=CYP11B1; Synonyms=S11BH;
DR   GuidetoPHARMACOLOGY; 1359; -.
DR   GO; GO:0020037; F:heme binding; IC:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0032342; P:aldosterone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0035865; P:cellular response to potassium ion; IEP:UniProtKB.
DR   GO; GO:0034651; P:cortisol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:BHF-UCL.
DR   GO; GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   C11B2_HUMAN             Reviewed;         503 AA.
AC   P19099; B0ZBE4; Q16726;
DE   RecName: Full=Cytochrome P450 11B2, mitochondrial;
DE   AltName: Full=Aldosterone synthase;
DE            Short=ALDOS;
DE            EC=1.14.15.4;
DE            EC=1.14.15.5;
DE   AltName: Full=Aldosterone-synthesizing enzyme;
DE   AltName: Full=CYPXIB2;
DE   AltName: Full=Cytochrome P-450Aldo;
DE   AltName: Full=Cytochrome P-450C18;
DE   AltName: Full=Steroid 18-hydroxylase;
DE   Flags: Precursor;
GN   Name=CYP11B2;
DR   GO; GO:0047783; F:corticosterone 18-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004507; F:steroid 11-beta-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0032342; P:aldosterone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0035865; P:cellular response to potassium ion; IEP:UniProtKB.
DR   GO; GO:0034651; P:cortisol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0055075; P:potassium ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0002017; P:regulation of blood volume by renal aldosterone; IMP:BHF-UCL.
DR   GO; GO:0003091; P:renal water homeostasis; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055078; P:sodium ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   C144A_HUMAN             Reviewed;        1427 AA.
AC   A2RUR9; O60311; Q6ZU57;
DE   RecName: Full=Coiled-coil domain-containing protein 144A;
GN   Name=CCDC144A; Synonyms=KIAA0565;
//
ID   C144C_HUMAN             Reviewed;        1237 AA.
AC   Q8IYA2; B7WNP5;
DE   RecName: Full=Putative coiled-coil domain-containing protein 144C;
DE   AltName: Full=Coiled-coil domain-containing protein 144C pseudogene;
GN   Name=CCDC144CP; Synonyms=CCDC144C;
//
ID   C144L_HUMAN             Reviewed;         221 AA.
AC   Q6NUI1;
DE   RecName: Full=Putative coiled-coil domain-containing protein 144 N-terminal-like;
GN   Name=CCDC144NL;
//
ID   C144B_HUMAN             Reviewed;         725 AA.
AC   Q3MJ40; Q6P5Q3; Q8N200;
DE   RecName: Full=Coiled-coil domain-containing protein 144B;
GN   Name=CCDC144B;
//
ID   C163A_HUMAN             Reviewed;        1156 AA.
AC   Q86VB7; C9JIG2; Q07898; Q07899; Q07900; Q07901; Q2VLH7;
DE   RecName: Full=Scavenger receptor cysteine-rich type 1 protein M130;
DE   AltName: Full=Hemoglobin scavenger receptor;
DE   AltName: CD_antigen=CD163;
DE   Contains:
DE     RecName: Full=Soluble CD163;
DE              Short=sCD163;
DE   Flags: Precursor;
GN   Name=CD163; Synonyms=M130;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; NAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:GOC.
//
ID   C163B_HUMAN             Reviewed;        1453 AA.
AC   Q9NR16; B4E0G7; C9JHR7; E7EVK4; Q2M3B7; Q6UWC2;
DE   RecName: Full=Scavenger receptor cysteine-rich type 1 protein M160;
DE   AltName: Full=CD163 antigen-like 1;
DE   AltName: CD_antigen=CD163b;
DE   Flags: Precursor;
GN   Name=CD163L1; Synonyms=CD163B, M160; ORFNames=UNQ6434/PRO23202;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
//
ID   C16L2_HUMAN             Reviewed;         174 AA.
AC   Q6UWJ8; B2RPJ0; Q5JXD6;
DE   RecName: Full=CD164 sialomucin-like 2 protein;
DE   Flags: Precursor;
GN   Name=CD164L2; ORFNames=UNQ6122/PRO20044;
//
ID   C170B_HUMAN             Reviewed;        1589 AA.
AC   Q9Y4F5; Q2KHR7; Q86TI7;
DE   RecName: Full=Centrosomal protein of 170 kDa protein B;
DE   AltName: Full=Centrosomal protein 170B;
DE            Short=Cep170B;
GN   Name=CEP170B; Synonyms=FAM68C, KIAA0284;
//
ID   C170L_HUMAN             Reviewed;         293 AA.
AC   Q96L14;
DE   RecName: Full=Cep170-like protein;
DE   AltName: Full=CEP170 pseudogene 1;
GN   Name=CEP170P1; Synonyms=CEP170L, KIAA0470L;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
//
ID   C19L1_HUMAN             Reviewed;         538 AA.
AC   Q69YN2; B4DHX1; D3DR66; Q5W0I3; Q96HC3; Q9H865; Q9NV13;
DE   RecName: Full=CWF19-like protein 1;
GN   Name=CWF19L1;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   C19L2_HUMAN             Reviewed;         894 AA.
AC   Q2TBE0; A4FU66; A4FU67; A4FU68; Q6PHW1; Q96MI1;
DE   RecName: Full=CWF19-like protein 2;
GN   Name=CWF19L2;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   C1AS1_HUMAN             Reviewed;         130 AA.
AC   Q8N1F1;
DE   RecName: Full=Putative uncharacterized protein LRRC75A-AS1, mitochondrial;
DE   AltName: Full=FAM211A antisense RNA 1;
DE   AltName: Full=LRRC75A antisense RNA 1;
DE   AltName: Full=Putative uncharacterized protein FAM211A-AS1, mitochondrial;
DE   Flags: Precursor;
GN   Name=LRRC75A-AS1;
GN   Synonyms=C17orf45, C17orf76-AS1, FAM211A-AS1, NCRNA00188;
//
ID   C1D_HUMAN               Reviewed;         141 AA.
AC   Q13901; A8K336; D6W5F8; Q05D64;
DE   RecName: Full=Nuclear nucleic acid-binding protein C1D;
DE            Short=hC1D;
GN   Name=C1D;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   C1GLC_HUMAN             Reviewed;         318 AA.
AC   Q96EU7; A8K246; Q8WWS3; Q9NZX1;
DE   RecName: Full=C1GALT1-specific chaperone 1;
DE   AltName: Full=C38H2-like protein 1;
DE            Short=C38H2-L1;
DE   AltName: Full=Core 1 beta1,3-galactosyltransferase 2;
DE            Short=C1Gal-T2;
DE            Short=C1GalT2;
DE            Short=Core 1 beta3-Gal-T2;
DE   AltName: Full=Core 1 beta3-galactosyltransferase-specific molecular chaperone;
GN   Name=C1GALT1C1; Synonyms=COSMC;
GN   ORFNames=HSPC067, MSTP143, UNQ273/PRO310;
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   C1GLT_HUMAN             Reviewed;         363 AA.
AC   Q9NS00; Q96QH4; Q9BTU1;
DE   RecName: Full=Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1;
DE            EC=2.4.1.122;
DE   AltName: Full=B3Gal-T8;
DE   AltName: Full=Core 1 O-glycan T-synthase;
DE   AltName: Full=Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1;
DE            Short=Beta-1,3-galactosyltransferase;
DE   AltName: Full=Core 1 beta1,3-galactosyltransferase 1;
DE            Short=C1GalT1;
DE            Short=Core 1 beta3-Gal-T1;
GN   Name=C1GALT1;
DR   GO; GO:0016263; F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IMP:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001822; P:kidney development; IMP:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   C1QA_HUMAN              Reviewed;         245 AA.
AC   P02745; B2R4X2; Q5T963;
DE   RecName: Full=Complement C1q subcomponent subunit A;
DE   Flags: Precursor;
GN   Name=C1QA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   C1QBP_HUMAN             Reviewed;         282 AA.
AC   Q07021; Q2HXR8; Q9NNY8;
DE   RecName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial;
DE   AltName: Full=ASF/SF2-associated protein p32;
DE   AltName: Full=Glycoprotein gC1qBP;
DE            Short=C1qBP;
DE   AltName: Full=Hyaluronan-binding protein 1;
DE   AltName: Full=Mitochondrial matrix protein p32;
DE   AltName: Full=gC1q-R protein;
DE   AltName: Full=p33;
DE   Flags: Precursor;
GN   Name=C1QBP; Synonyms=GC1QBP, HABP1, SF2P32;
DR   GO; GO:0031690; F:adrenergic receptor binding; ISS:UniProtKB.
DR   GO; GO:0001849; F:complement component C1q binding; IDA:UniProtKB.
DR   GO; GO:0005540; F:hyaluronic acid binding; IDA:UniProtKB.
DR   GO; GO:0030984; F:kininogen binding; IDA:UniProtKB.
DR   GO; GO:0097177; F:mitochondrial ribosome binding; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0042256; P:mature ribosome assembly; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IDA:UniProtKB.
DR   GO; GO:0039534; P:negative regulation of MDA-5 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0039536; P:negative regulation of RIG-I signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:2000510; P:positive regulation of dendritic cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0070131; P:positive regulation of mitochondrial translation; ISS:UniProtKB.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IMP:UniProtKB.
DR   GO; GO:1901165; P:positive regulation of trophoblast cell migration; IMP:UniProtKB.
DR   GO; GO:0030449; P:regulation of complement activation; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   C1QB_HUMAN              Reviewed;         253 AA.
AC   P02746; Q5T959; Q96H17;
DE   RecName: Full=Complement C1q subcomponent subunit B;
DE   Flags: Precursor;
GN   Name=C1QB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
//
ID   C1QC_HUMAN              Reviewed;         245 AA.
AC   P02747; Q7Z502; Q96DL2; Q96H05;
DE   RecName: Full=Complement C1q subcomponent subunit C;
DE   Flags: Precursor;
GN   Name=C1QC; Synonyms=C1QG;
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030853; P:negative regulation of granulocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; IDA:BHF-UCL.
//
ID   C1QL2_HUMAN             Reviewed;         287 AA.
AC   Q7Z5L3;
DE   RecName: Full=Complement C1q-like protein 2;
DE   AltName: Full=C1q and tumor necrosis factor-related protein 10;
DE            Short=C1q/TNF-related protein 10;
DE   Flags: Precursor;
GN   Name=C1QL2; Synonyms=CTRP10;
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
//
ID   C1QL3_HUMAN             Reviewed;         255 AA.
AC   Q5VWW1; A0PJY4; A0PJY5;
DE   RecName: Full=Complement C1q-like protein 3;
DE   AltName: Full=C1q and tumor necrosis factor-related protein 13;
DE            Short=C1q/TNF-related protein 13;
DE   Flags: Precursor;
GN   Name=C1QL3; Synonyms=CTRP13;
DR   GO; GO:0050807; P:regulation of synapse organization; IEA:Ensembl.
//
ID   C1QL4_HUMAN             Reviewed;         238 AA.
AC   Q86Z23;
DE   RecName: Full=Complement C1q-like protein 4;
DE   AltName: Full=C1q and tumor necrosis factor-related protein 11;
DE            Short=C1q/TNF-related protein 11;
DE   Flags: Precursor;
GN   Name=C1QL4; Synonyms=CTRP11;
//
ID   C1QR1_HUMAN             Reviewed;         652 AA.
AC   Q9NPY3; O00274;
DE   RecName: Full=Complement component C1q receptor;
DE   AltName: Full=C1q/MBL/SPA receptor;
DE            Short=C1qR;
DE            Short=C1qR(p);
DE            Short=C1qRp;
DE   AltName: Full=CDw93;
DE   AltName: Full=Complement component 1 q subcomponent receptor 1;
DE   AltName: Full=Matrix-remodeling-associated protein 4;
DE   AltName: CD_antigen=CD93;
DE   Flags: Precursor;
GN   Name=CD93; Synonyms=C1QR1, MXRA4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0001849; F:complement component C1q binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0042116; P:macrophage activation; NAS:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   C1QRF_HUMAN             Reviewed;         258 AA.
AC   O75973;
DE   RecName: Full=C1q-related factor;
DE   AltName: Full=C1q and tumor necrosis factor-related protein 14;
DE            Short=C1q/TNF-related protein 14;
DE   AltName: Full=Complement component 1 Q subcomponent-like 1;
DE   Flags: Precursor;
GN   Name=C1QL1; Synonyms=C1QRF, CRF, CTRP14;
DR   GO; GO:0007626; P:locomotory behavior; NAS:UniProtKB.
//
ID   C1QT1_HUMAN             Reviewed;         281 AA.
AC   Q9BXJ1; Q96NF2; Q9GZR4;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 1;
DE   AltName: Full=G protein-coupled receptor-interacting protein;
DE            Short=GIP;
DE   Flags: Precursor;
GN   Name=C1QTNF1; Synonyms=CTRP1; ORFNames=UNQ310/PRO353;
DR   GO; GO:0005518; F:collagen binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IDA:UniProt.
DR   GO; GO:0090331; P:negative regulation of platelet aggregation; IDA:UniProt.
DR   GO; GO:2000860; P:positive regulation of aldosterone secretion; IDA:UniProt.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProt.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProt.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IEA:Ensembl.
//
ID   C1QT2_HUMAN             Reviewed;         285 AA.
AC   Q9BXJ5;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 2;
DE   Flags: Precursor;
GN   Name=C1QTNF2; Synonyms=CTRP2; ORFNames=UNQ6349/PRO21054;
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0046321; P:positive regulation of fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
//
ID   C1QT4_HUMAN             Reviewed;         329 AA.
AC   Q9BXJ3; Q8IV25;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 4;
DE   Flags: Precursor;
GN   Name=C1QTNF4; Synonyms=CTRP4;
//
ID   C1QT3_HUMAN             Reviewed;         246 AA.
AC   Q9BXJ4; Q0VAN4; Q542Y2; Q6MZN1; Q96KY1;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 3;
DE   AltName: Full=Collagenous repeat-containing sequence 26 kDa protein;
DE            Short=CORS26;
DE   AltName: Full=Secretory protein CORS26;
DE   Flags: Precursor;
GN   Name=C1QTNF3; Synonyms=CTRP3; ORFNames=UNQ753/PRO1484;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035356; P:cellular triglyceride homeostasis; IDA:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEP:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IDA:MGI.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:1900165; P:negative regulation of interleukin-6 secretion; IDA:UniProtKB.
DR   GO; GO:0071638; P:negative regulation of monocyte chemotactic protein-1 production; IDA:UniProtKB.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IDA:UniProtKB.
DR   GO; GO:0070165; P:positive regulation of adiponectin secretion; IDA:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
//
ID   C1QT5_HUMAN             Reviewed;         243 AA.
AC   Q9BXJ0; A6NDD3; B0YJ35; Q335M2; Q8N6P2; Q9UFX4;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 5;
DE   Flags: Precursor;
GN   Name=C1QTNF5; Synonyms=CTRP5; ORFNames=UNQ303/PRO344;
//
ID   C1QT6_HUMAN             Reviewed;         259 AA.
AC   Q9BXI9; Q5H9G8; Q6ZRM7;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 6;
DE   Flags: Precursor;
GN   Name=C1QTNF6; Synonyms=CTRP6; ORFNames=UNQ581/PRO1151;
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
//
ID   C1QT7_HUMAN             Reviewed;         289 AA.
AC   Q9BXJ2; B2RBT3; J3KPW3;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 7;
DE   Flags: Precursor;
GN   Name=C1QTNF7; Synonyms=CTRP7;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
//
ID   C1QT8_HUMAN             Reviewed;         252 AA.
AC   P60827; B7U178;
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 8;
DE   AltName: Full=C1q/TNF-related protein 8;
DE            Short=CTRP8;
DE   Flags: Precursor;
GN   Name=C1QTNF8; ORFNames=UNQ5829/PRO19648;
//
ID   C1RL_HUMAN              Reviewed;         487 AA.
AC   Q9NZP8; Q53GX9;
DE   RecName: Full=Complement C1r subcomponent-like protein;
DE            Short=C1r-LP;
DE            Short=C1r-like protein;
DE            EC=3.4.21.-;
DE   AltName: Full=C1r-like serine protease analog protein;
DE            Short=CLSPa;
DE   Flags: Precursor;
GN   Name=C1RL; Synonyms=C1RL1, C1RLP, CLSPA;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   C1R_HUMAN               Reviewed;         705 AA.
AC   P00736; A6NJQ8; Q68D77; Q8J012;
DE   RecName: Full=Complement C1r subcomponent;
DE            EC=3.4.21.41;
DE   AltName: Full=Complement component 1 subcomponent r;
DE   Contains:
DE     RecName: Full=Complement C1r subcomponent heavy chain;
DE   Contains:
DE     RecName: Full=Complement C1r subcomponent light chain;
DE   Flags: Precursor;
GN   Name=C1R;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; EXP:Reactome.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   C1S_HUMAN               Reviewed;         688 AA.
AC   P09871; D3DUT4; Q9UCU7; Q9UCU8; Q9UCU9; Q9UCV0; Q9UCV1; Q9UCV2;
AC   Q9UCV3; Q9UCV4; Q9UCV5; Q9UM14;
DE   RecName: Full=Complement C1s subcomponent;
DE            EC=3.4.21.42;
DE   AltName: Full=C1 esterase;
DE   AltName: Full=Complement component 1 subcomponent s;
DE   Contains:
DE     RecName: Full=Complement C1s subcomponent heavy chain;
DE   Contains:
DE     RecName: Full=Complement C1s subcomponent light chain;
DE   Flags: Precursor;
GN   Name=C1S;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   C1T9A_HUMAN             Reviewed;         333 AA.
AC   P0C862; A2A3T6; Q0VGC5; Q5VX65; Q5VX66; Q8IUU4;
DE   RecName: Full=Complement C1q and tumor necrosis factor-related protein 9A;
DE   AltName: Full=Complement C1q and tumor necrosis factor-related protein 9;
DE   Flags: Precursor;
GN   Name=C1QTNF9; Synonyms=C1QTNF9A; ORFNames=UNQ6503/PRO21380;
//
ID   C1T9B_HUMAN             Reviewed;         333 AA.
AC   B2RNN3; A2A3T6; B9EH31; Q0VGC5; Q5VX65; Q5VX66; Q8IUU4;
DE   RecName: Full=Complement C1q and tumor necrosis factor-related protein 9B;
DE   AltName: Full=C1q/TNF-related protein 9B;
DE            Short=CTRP9B;
DE   AltName: Full=Complement C1q and tumor necrosis factor-related protein 9-like;
DE   Flags: Precursor;
GN   Name=C1QTNF9B;
//
ID   C1TC_HUMAN              Reviewed;         935 AA.
AC   P11586; B2R5Y2; G3V2B8; Q86VC9; Q9BVP5;
DE   RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic;
DE            Short=C1-THF synthase;
DE   Includes:
DE     RecName: Full=Methylenetetrahydrofolate dehydrogenase;
DE              EC=1.5.1.5;
DE   Includes:
DE     RecName: Full=Methenyltetrahydrofolate cyclohydrolase;
DE              EC=3.5.4.9;
DE   Includes:
DE     RecName: Full=Formyltetrahydrofolate synthetase;
DE              EC=6.3.4.3;
DE   Contains:
DE     RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;
GN   Name=MTHFD1; Synonyms=MTHFC, MTHFD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004329; F:formate-tetrahydrofolate ligase activity; IBA:RefGenome.
DR   GO; GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IBA:RefGenome.
DR   GO; GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IBA:RefGenome.
DR   GO; GO:0004486; F:methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity; TAS:Reactome.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IBA:RefGenome.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   C1TM_HUMAN              Reviewed;         978 AA.
AC   Q6UB35; Q2TBF3; Q8WVW0; Q96HG8; Q9H789; Q9UFU8;
DE   RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial;
DE            EC=6.3.4.3;
DE   AltName: Full=Formyltetrahydrofolate synthetase;
DE   Flags: Precursor;
GN   Name=MTHFD1L; Synonyms=FTHFSDC1;
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0004329; F:formate-tetrahydrofolate ligase activity; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   GO; GO:0006760; P:folic acid-containing compound metabolic process; IDA:BHF-UCL.
DR   GO; GO:0015942; P:formate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006730; P:one-carbon metabolic process; IBA:RefGenome.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:InterPro.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IDA:BHF-UCL.
//
ID   C27C1_HUMAN             Reviewed;         372 AA.
AC   Q4G0S4; Q6ZNI7;
DE   RecName: Full=Cytochrome P450 27C1;
DE            EC=1.14.-.-;
GN   Name=CYP27C1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
//
ID   C2AIL_HUMAN             Reviewed;         116 AA.
AC   Q96HQ2; Q8WVE3;
DE   RecName: Full=CDKN2AIP N-terminal-like protein;
DE   AltName: Full=CDKN2A-interacting protein N-terminal-like protein;
GN   Name=CDKN2AIPNL;
//
ID   C2AS1_HUMAN             Reviewed;         134 AA.
AC   Q96NR2; Q52LN1;
DE   RecName: Full=Putative uncharacterized protein C20orf166-AS1;
DE   AltName: Full=C20orf166 antisense RNA 1;
DE   AltName: Full=C20orf166 antisense gene protein 1;
GN   Name=C20orf166-AS1; Synonyms=C20orf200, NCRNA00335;
//
ID   C2C2L_HUMAN             Reviewed;         706 AA.
AC   O14523; Q86UT7; Q86V04; Q8N522; Q8TBN4; Q96G10;
DE   RecName: Full=C2 domain-containing protein 2-like;
DE   AltName: Full=Transmembrane protein 24;
GN   Name=C2CD2L; Synonyms=KIAA0285, TMEM24; ORFNames=DLNB23;
//
ID   C2C4A_HUMAN             Reviewed;         369 AA.
AC   Q8NCU7;
DE   RecName: Full=C2 calcium-dependent domain-containing protein 4A;
DE   AltName: Full=Nuclear-localized factor 1;
DE   AltName: Full=Protein FAM148A;
GN   Name=C2CD4A; Synonyms=FAM148A, NLF1;
//
ID   C2C4B_HUMAN             Reviewed;         364 AA.
AC   A6NLJ0;
DE   RecName: Full=C2 calcium-dependent domain-containing protein 4B;
DE   AltName: Full=Nuclear-localized factor 2;
DE   AltName: Full=Protein FAM148B;
GN   Name=C2CD4B; Synonyms=FAM148B, NLF2;
//
ID   C2C4C_HUMAN             Reviewed;         421 AA.
AC   Q8TF44; Q8N3H7;
DE   RecName: Full=C2 calcium-dependent domain-containing protein 4C;
DE   AltName: Full=Nuclear-localized factor 3;
DE   AltName: Full=Protein FAM148C;
GN   Name=C2CD4C; Synonyms=FAM148C, KIAA1957, NLF3;
//
ID   C2CD3_HUMAN             Reviewed;        2353 AA.
AC   Q4AC94; C9JR55; E2QRD1; Q2NLE1; Q3C1U9; Q6ZU92; Q8IYM4; Q8NB87;
AC   Q8NDH7; Q9Y4M2;
DE   RecName: Full=C2 domain-containing protein 3;
GN   Name=C2CD3;
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0021997; P:neural plate axis specification; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; IMP:UniProtKB.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
//
ID   C2CD5_HUMAN             Reviewed;        1000 AA.
AC   Q86YS7; B4DRN7; O60280; Q17RY7; Q7Z619; Q86SU3;
DE   RecName: Full=C2 domain-containing protein 5;
DE   AltName: Full=C2 domain-containing phosphoprotein of 138 kDa;
GN   Name=C2CD5; Synonyms=CDP138, KIAA0528;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0038028; P:insulin receptor signaling pathway via phosphatidylinositol 3-kinase; ISS:UniProtKB.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IMP:UniProtKB.
DR   GO; GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0010828; P:positive regulation of glucose transport; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; IMP:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0006906; P:vesicle fusion; IEA:Ensembl.
//
ID   C2D1A_HUMAN             Reviewed;         951 AA.
AC   Q6P1N0; Q7Z435; Q86XV0; Q8NF89; Q9H603; Q9NXI1;
DE   RecName: Full=Coiled-coil and C2 domain-containing protein 1A;
DE   AltName: Full=Akt kinase-interacting protein 1;
DE   AltName: Full=Five prime repressor element under dual repression-binding protein 1;
DE            Short=FRE under dual repression-binding protein 1;
DE            Short=Freud-1;
DE   AltName: Full=Putative NF-kappa-B-activating protein 023N;
GN   Name=CC2D1A; Synonyms=AKI1;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   C2D1B_HUMAN             Reviewed;         858 AA.
AC   Q5T0F9; Q49AE8; Q5T0F8; Q5T0G0; Q6ZNQ1; Q96AP3; Q96I04; Q96JJ1;
DE   RecName: Full=Coiled-coil and C2 domain-containing protein 1B;
DE   AltName: Full=Five prime repressor element under dual repression-binding protein 2;
DE            Short=FRE under dual repression-binding protein 2;
DE            Short=Freud-2;
GN   Name=CC2D1B; Synonyms=KIAA1836;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
//
ID   C2D2A_HUMAN             Reviewed;        1620 AA.
AC   Q9P2K1; A6ND97; B3FW08; D6RB72; E7EP21; E9PEV5; Q3SYP3; Q9H8A7;
DE   RecName: Full=Coiled-coil and C2 domain-containing protein 2A;
GN   Name=CC2D2A; Synonyms=KIAA1345;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   C2D4D_HUMAN             Reviewed;         353 AA.
AC   B7Z1M9; B2RXG8;
DE   RecName: Full=C2 calcium-dependent domain-containing protein 4D;
GN   Name=C2CD4D; Synonyms=FAM148D;
//
ID   C2D2B_HUMAN             Reviewed;         322 AA.
AC   Q6DHV5; A2A3E9; B4DYD4; E9PCC3; Q5VUS0;
DE   RecName: Full=Protein CC2D2B;
GN   Name=CC2D2B; Synonyms=C10orf130;
//
ID   C2G1P_HUMAN             Reviewed;         146 AA.
AC   Q6ZSU1;
DE   RecName: Full=Putative inactive cytochrome P450 2G1;
DE   AltName: Full=Cytochrome P450 2G1 pseudogene;
GN   Name=CYP2G1P; Synonyms=CYP2GP1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
//
ID   C2TA_HUMAN              Reviewed;        1130 AA.
AC   P33076; D3DUG0;
DE   RecName: Full=MHC class II transactivator;
DE            Short=CIITA;
GN   Name=CIITA; Synonyms=MHC2TA;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032966; P:negative regulation of collagen biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045345; P:positive regulation of MHC class I biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0046677; P:response to antibiotic; IDA:MGI.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   C3AR_HUMAN              Reviewed;         482 AA.
AC   Q16581; O43771; Q92868;
DE   RecName: Full=C3a anaphylatoxin chemotactic receptor;
DE            Short=C3AR;
DE            Short=C3a-R;
GN   Name=C3AR1; Synonyms=AZ3B, C3R1, HNFAG09;
DR   GuidetoPHARMACOLOGY; 31; -.
DR   GO; GO:0004943; F:C3a anaphylatoxin receptor activity; TAS:ProtInc.
DR   GO; GO:0004876; F:complement component C3a receptor activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IGI:UniProtKB.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0002430; P:complement receptor mediated signaling pathway; TAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IGI:UniProtKB.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IEA:Ensembl.
//
ID   C3P1_HUMAN              Reviewed;         363 AA.
AC   Q6ZMU1;
DE   RecName: Full=Putative protein C3P1;
GN   Name=C3P1;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
//
ID   C42S1_HUMAN             Reviewed;          79 AA.
AC   Q9NRR8; D3DV12; Q9HB17; Q9NQR2;
DE   RecName: Full=CDC42 small effector protein 1;
DE   AltName: Full=CDC42-binding protein SCIP1;
DE   AltName: Full=Small effector of CDC42 protein 1;
GN   Name=CDC42SE1; Synonyms=SPEC1;
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   C42S2_HUMAN             Reviewed;          84 AA.
AC   Q9NRR3; B2R622; Q4KMT9;
DE   RecName: Full=CDC42 small effector protein 2;
DE   AltName: Full=Small effector of CDC42 protein 2;
GN   Name=CDC42SE2; Synonyms=SPEC2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0009966; P:regulation of signal transduction; IDA:UniProtKB.
//
ID   C43BP_HUMAN             Reviewed;         624 AA.
AC   Q9Y5P4; A8K7S2; B3KUB7; Q53YV1; Q53YV2; Q96Q85; Q96Q88; Q9H2S7;
AC   Q9H2S8;
DE   RecName: Full=Collagen type IV alpha-3-binding protein;
DE   AltName: Full=Ceramide transfer protein;
DE            Short=hCERT;
DE   AltName: Full=Goodpasture antigen-binding protein;
DE            Short=GPBP;
DE   AltName: Full=START domain-containing protein 11;
DE            Short=StARD11;
DE   AltName: Full=StAR-related lipid transfer protein 11;
GN   Name=COL4A3BP; Synonyms=CERT, STARD11;
DR   GO; GO:0097001; F:ceramide binding; IDA:UniProtKB.
DR   GO; GO:0035620; F:ceramide transporter activity; IDA:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006672; P:ceramide metabolic process; IEA:Ensembl.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:Ensembl.
DR   GO; GO:0035621; P:ER to Golgi ceramide transport; IMP:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0055088; P:lipid homeostasis; IEA:Ensembl.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   C4BPA_HUMAN             Reviewed;         597 AA.
AC   P04003; Q5VVQ8;
DE   RecName: Full=C4b-binding protein alpha chain;
DE            Short=C4bp;
DE   AltName: Full=Proline-rich protein;
DE            Short=PRP;
DE   Flags: Precursor;
GN   Name=C4BPA; Synonyms=C4BP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   C4BPB_HUMAN             Reviewed;         252 AA.
AC   P20851; A5JYP8; D3DT81; Q5VVR0; Q9BS25;
DE   RecName: Full=C4b-binding protein beta chain;
DE   Flags: Precursor;
GN   Name=C4BPB;
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   C4F30_HUMAN             Reviewed;         118 AA.
AC   Q9H0H9;
DE   RecName: Full=Putative cytochrome P450 family member 4F30;
GN   Name=CYP4F30P; Synonyms=C2orf14;
//
ID   C560_HUMAN              Reviewed;         169 AA.
AC   Q99643; O75609; Q3C259; Q3C2D8; Q3C2H4; Q5VTH3;
DE   RecName: Full=Succinate dehydrogenase cytochrome b560 subunit, mitochondrial;
DE   AltName: Full=Integral membrane protein CII-3;
DE   AltName: Full=QPs-1;
DE            Short=QPs1;
DE   AltName: Full=Succinate dehydrogenase complex subunit C;
DE   AltName: Full=Succinate-ubiquinone oxidoreductase cytochrome B large subunit;
DE            Short=CYBL;
DE   Flags: Precursor;
GN   Name=SDHC; Synonyms=CYB560, SDH3;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000104; F:succinate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; TAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:UniProtKB.
//
ID   C56D1_HUMAN             Reviewed;         229 AA.
AC   Q8N8Q1; B4DH97; E9PCM8; Q52M36; Q5T6C2; Q5T6C3;
DE   RecName: Full=Cytochrome b561 domain-containing protein 1;
GN   Name=CYB561D1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
//
ID   C56D2_HUMAN             Reviewed;         222 AA.
AC   O14569; A8K552;
DE   RecName: Full=Cytochrome b561 domain-containing protein 2;
DE   AltName: Full=Putative tumor suppressor protein 101F6;
GN   Name=CYB561D2; Synonyms=101F6; ORFNames=LUCA12.2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
//
ID   C5AR1_HUMAN             Reviewed;         350 AA.
AC   P21730;
DE   RecName: Full=C5a anaphylatoxin chemotactic receptor 1;
DE   AltName: Full=C5a anaphylatoxin chemotactic receptor;
DE            Short=C5a-R;
DE            Short=C5aR;
DE   AltName: CD_antigen=CD88;
GN   Name=C5AR1; Synonyms=C5AR, C5R1;
DR   GuidetoPHARMACOLOGY; 32; -.
DR   GO; GO:0004944; F:C5a anaphylatoxin receptor activity; IDA:UniProtKB.
DR   GO; GO:0004878; F:complement component C5a receptor activity; IDA:UniProtKB.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0021534; P:cell proliferation in hindbrain; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0038178; P:complement component C5a signaling pathway; IDA:GOC.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0032494; P:response to peptidoglycan; IEA:Ensembl.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   C5AR2_HUMAN             Reviewed;         337 AA.
AC   Q9P296; B2RA09;
DE   RecName: Full=C5a anaphylatoxin chemotactic receptor 2;
DE   AltName: Full=Complement component 5a receptor 2;
DE   AltName: Full=G-protein coupled receptor 77;
GN   Name=C5AR2; Synonyms=C5L2, GPR77;
DR   GuidetoPHARMACOLOGY; 33; -.
DR   GO; GO:0004944; F:C5a anaphylatoxin receptor activity; IEA:InterPro.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:1900165; P:negative regulation of interleukin-6 secretion; IMP:UniProtKB.
DR   GO; GO:0090024; P:negative regulation of neutrophil chemotaxis; IMP:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.
DR   GO; GO:2000482; P:regulation of interleukin-8 secretion; IMP:UniProtKB.
//
ID   C8AP2_HUMAN             Reviewed;        1982 AA.
AC   Q9UKL3; A2RUB7; E1P553; Q6PH76; Q7LCQ7; Q86YD9; Q9NUQ4; Q9NZV9;
AC   Q9P2N1; Q9Y563;
DE   RecName: Full=CASP8-associated protein 2;
DE   AltName: Full=FLICE-associated huge protein;
GN   Name=CASP8AP2; Synonyms=FLASH, KIAA1315, RIP25;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0005123; F:death receptor binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016505; F:peptidase activator activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032184; F:SUMO polymer binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:0036337; P:Fas signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CA043_HUMAN             Reviewed;         253 AA.
AC   Q9BWL3; A8K3G8; D3DV72; D3DV74; Q5M801; Q5VU73; Q5VU83; Q96HP7;
AC   Q9UFU2; Q9UGL7; Q9UGL8; Q9Y2R6;
DE   RecName: Full=Uncharacterized protein C1orf43;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 4;
DE            Short=HCV NS5A-transactivated protein 4;
DE   AltName: Full=Protein NICE-3;
DE   AltName: Full=S863-3;
GN   Name=C1orf43; Synonyms=NICE3, NS5ATP4; ORFNames=HSPC012;
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
//
ID   CA021_HUMAN             Reviewed;         121 AA.
AC   Q9H246; B2R551;
DE   RecName: Full=Uncharacterized protein C1orf21;
DE   AltName: Full=Cell proliferation-inducing gene 13 protein;
GN   Name=C1orf21; ORFNames=PIG13;
//
ID   CA050_HUMAN             Reviewed;         199 AA.
AC   Q9BV19;
DE   RecName: Full=Uncharacterized protein C1orf50;
GN   Name=C1orf50;
//
ID   C99L2_HUMAN             Reviewed;         262 AA.
AC   Q8TCZ2; A8K2D5; A8K5R0; B3KWG2; B4DDL7; E7EMK5; E9PD27; Q8TAW2;
AC   Q8TCZ0; Q8TCZ1; Q9BQG9;
DE   RecName: Full=CD99 antigen-like protein 2;
DE   AltName: Full=MIC2-like protein 1;
DE   AltName: CD_antigen=CD99;
DE   Flags: Precursor;
GN   Name=CD99L2; Synonyms=MIC2L1; ORFNames=UNQ1964/PRO4486;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CA052_HUMAN             Reviewed;         182 AA.
AC   Q8N6N3; B3KX89; Q8TDK5; Q8TDK6;
DE   RecName: Full=UPF0690 protein C1orf52;
DE   AltName: Full=BCL10-associated gene protein;
GN   Name=C1orf52; Synonyms=BAG; ORFNames=GM117;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CA053_HUMAN             Reviewed;         145 AA.
AC   Q5VUE5; A1L4N2; Q5VUE4;
DE   RecName: Full=Uncharacterized protein C1orf53;
GN   Name=C1orf53;
//
ID   CA064_HUMAN             Reviewed;         169 AA.
AC   Q8NEQ6; B3KXI9;
DE   RecName: Full=Uncharacterized protein C1orf64;
GN   Name=C1orf64;
//
ID   CA054_HUMAN             Reviewed;         131 AA.
AC   Q8WWF1; Q9H5P3;
DE   RecName: Full=Uncharacterized protein C1orf54;
DE   Flags: Precursor;
GN   Name=C1orf54;
//
ID   CA074_HUMAN             Reviewed;         269 AA.
AC   Q96LT6;
DE   RecName: Full=UPF0739 protein C1orf74;
GN   Name=C1orf74;
//
ID   CA097_HUMAN             Reviewed;          94 AA.
AC   Q9BRT7;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00467;
GN   Name=LINC00467; Synonyms=C1orf97;
//
ID   CA100_HUMAN             Reviewed;         147 AA.
AC   Q5SVJ3; Q5SVJ4;
DE   RecName: Full=Uncharacterized protein C1orf100;
GN   Name=C1orf100;
//
ID   CA087_HUMAN             Reviewed;         546 AA.
AC   Q8N0U7; Q6ZU07; Q8IVS0;
DE   RecName: Full=Uncharacterized protein C1orf87;
GN   Name=C1orf87;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CA094_HUMAN             Reviewed;         598 AA.
AC   Q6P1W5; B3KVT1; D3DPR3; E9PJ76; Q96IC8;
DE   RecName: Full=Uncharacterized protein C1orf94;
GN   Name=C1orf94;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CA101_HUMAN             Reviewed;         951 AA.
AC   Q5SY80; B4DZR4; B7Z7X5; E9PEA3; Q8IYZ6;
DE   RecName: Full=Uncharacterized protein C1orf101;
DE   Flags: Precursor;
GN   Name=C1orf101;
//
ID   CA105_HUMAN             Reviewed;         183 AA.
AC   O95561; Q8IY02;
DE   RecName: Full=Uncharacterized protein C1orf105;
GN   Name=C1orf105;
//
ID   CA109_HUMAN             Reviewed;         203 AA.
AC   Q9NX04; D3DPT1; Q8WVD1;
DE   RecName: Full=Uncharacterized protein C1orf109;
GN   Name=C1orf109;
//
ID   CA110_HUMAN             Reviewed;         302 AA.
AC   Q86UF4; Q5JSG1; Q6ZW57;
DE   RecName: Full=Coiled-coil domain-containing protein C1orf110;
GN   Name=C1orf110;
//
ID   CA111_HUMAN             Reviewed;         261 AA.
AC   Q5T0L3; Q6X961; Q8NEC3;
DE   RecName: Full=Uncharacterized protein C1orf111;
GN   Name=C1orf111; ORFNames=HSD20;
//
ID   CA106_HUMAN             Reviewed;         663 AA.
AC   Q3KP66; B4E1K9; E9PFY0; Q9NV65; Q9NVI0;
DE   RecName: Full=Uncharacterized protein C1orf106;
GN   Name=C1orf106;
//
ID   CA112_HUMAN             Reviewed;         853 AA.
AC   Q9NSG2; A6NFP1; B3KU42; Q3KNQ1; Q9H8L5; Q9NVJ0;
DE   RecName: Full=Uncharacterized protein C1orf112;
GN   Name=C1orf112;
//
ID   CA115_HUMAN             Reviewed;         142 AA.
AC   Q9H7X2; B3KRN3; D3DTB2;
DE   RecName: Full=Uncharacterized protein C1orf115;
GN   Name=C1orf115;
//
ID   CA127_HUMAN             Reviewed;         656 AA.
AC   Q8N9H9; A0AVG8; A6NKM7; Q5VXJ2;
DE   RecName: Full=Uncharacterized protein C1orf127;
GN   Name=C1orf127;
//
ID   CA122_HUMAN             Reviewed;         110 AA.
AC   Q6ZSJ8; A2RQF4; E9PQ13; Q56A71;
DE   RecName: Full=Uncharacterized protein C1orf122;
DE   AltName: Full=Protein ALAESM;
GN   Name=C1orf122;
//
ID   CA123_HUMAN             Reviewed;         160 AA.
AC   Q9NWV4;
DE   RecName: Full=UPF0587 protein C1orf123;
GN   Name=C1orf123;
//
ID   CA131_HUMAN             Reviewed;         294 AA.
AC   Q8NDD1; Q5TBI0; Q5TBI1; Q6P6B4; Q7Z6H5; Q8N432; Q96NM6;
DE   RecName: Full=Uncharacterized protein C1orf131;
GN   Name=C1orf131;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CA134_HUMAN             Reviewed;          83 AA.
AC   Q5TEV5;
DE   RecName: Full=Putative uncharacterized protein C1orf134;
DE   Flags: Precursor;
GN   Name=C1orf134;
//
ID   CA137_HUMAN             Reviewed;          98 AA.
AC   Q5JT78;
DE   RecName: Full=Putative uncharacterized protein C1orf137;
GN   Name=C1orf137;
//
ID   CA140_HUMAN             Reviewed;         124 AA.
AC   Q5VVS0; Q6ZR57;
DE   RecName: Full=Putative uncharacterized protein C1orf140;
GN   Name=C1orf140;
//
ID   CA141_HUMAN             Reviewed;         400 AA.
AC   Q5JVX7; Q0P5P5; Q5JVX5;
DE   RecName: Full=Uncharacterized protein C1orf141;
GN   Name=C1orf141;
//
ID   CA146_HUMAN             Reviewed;         180 AA.
AC   Q5VVC0; Q5VVC4;
DE   RecName: Full=Uncharacterized protein C1orf146;
GN   Name=C1orf146;
//
ID   CA147_HUMAN             Reviewed;         270 AA.
AC   Q96MC9; Q5JTS5;
DE   RecName: Full=Uncharacterized protein C1orf147;
GN   Name=C1orf147;
//
ID   CA145_HUMAN             Reviewed;         158 AA.
AC   Q96MR7; Q5T438; Q8N372;
DE   RecName: Full=Putative uncharacterized protein C1orf145;
GN   Name=C1orf145;
//
ID   CA158_HUMAN             Reviewed;         194 AA.
AC   Q8N1D5; Q5VUY4;
DE   RecName: Full=Uncharacterized protein C1orf158;
GN   Name=C1orf158;
//
ID   CA157_HUMAN             Reviewed;         128 AA.
AC   Q3SY05; Q3SY06; Q8N7U1;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00303;
GN   Name=LINC00303; Synonyms=C1orf157, NCRNA00303;
//
ID   CA159_HUMAN             Reviewed;         380 AA.
AC   Q96HA4; B3KQ46; Q5T2W6; Q6UX67; Q6ZR77; Q9NWV0;
DE   RecName: Full=Uncharacterized protein C1orf159;
DE   Flags: Precursor;
GN   Name=C1orf159; ORFNames=UNQ2998/PRO9739;
//
ID   CA167_HUMAN             Reviewed;        1468 AA.
AC   Q5SNV9; Q8NDA9; Q8NDF3;
DE   RecName: Full=Uncharacterized protein C1orf167;
GN   Name=C1orf167;
//
ID   CA162_HUMAN             Reviewed;         155 AA.
AC   Q8NEQ5; Q5QNZ1;
DE   RecName: Full=Transmembrane protein C1orf162;
GN   Name=C1orf162;
//
ID   CA168_HUMAN             Reviewed;         728 AA.
AC   Q5VWT5; Q63HM3; Q6ZUY6;
DE   RecName: Full=Uncharacterized protein C1orf168;
GN   Name=C1orf168;
//
ID   CA172_HUMAN             Reviewed;         398 AA.
AC   Q8NAX2; Q5QP32; Q8N0S7;
DE   RecName: Full=Uncharacterized protein C1orf172;
GN   Name=C1orf172;
//
ID   CA177_HUMAN             Reviewed;         418 AA.
AC   Q3ZCV2; B7WPL2; Q8N7Y9;
DE   RecName: Full=Uncharacterized protein C1orf177;
GN   Name=C1orf177;
//
ID   CA180_HUMAN             Reviewed;         123 AA.
AC   Q8NAE3;
DE   RecName: Full=Putative uncharacterized protein C1orf180;
GN   Name=C1orf180;
//
ID   CA185_HUMAN             Reviewed;         199 AA.
AC   Q5T7R7; A6NHS3;
DE   RecName: Full=Uncharacterized protein C1orf185;
GN   Name=C1orf185;
//
ID   CA186_HUMAN             Reviewed;         172 AA.
AC   Q6ZWK4;
DE   RecName: Full=Uncharacterized protein C1orf186;
GN   Name=C1orf186;
//
ID   CA189_HUMAN             Reviewed;         101 AA.
AC   Q5VU69; A1L4E3;
DE   RecName: Full=Uncharacterized protein C1orf189;
GN   Name=C1orf189;
//
ID   CA192_HUMAN             Reviewed;         177 AA.
AC   Q5VTH2;
DE   RecName: Full=UPF0740 protein C1orf192;
GN   Name=C1orf192;
//
ID   CA174_HUMAN             Reviewed;         243 AA.
AC   Q8IYL3; A8K0C8; A8MUG9; Q5SR20; Q6NX36;
DE   RecName: Full=UPF0688 protein C1orf174;
GN   Name=C1orf174;
//
ID   CA194_HUMAN             Reviewed;         169 AA.
AC   Q5T5A4; Q5T5A3;
DE   RecName: Full=Uncharacterized protein C1orf194;
GN   Name=C1orf194;
//
ID   CA198_HUMAN             Reviewed;         327 AA.
AC   Q9H425; A8K8R8; B3KTW1; G5EA08;
DE   RecName: Full=Uncharacterized protein C1orf198;
GN   Name=C1orf198;
//
ID   CA196_HUMAN             Reviewed;         125 AA.
AC   B1AJZ1;
DE   RecName: Full=Putative uncharacterized protein C1orf196;
GN   Name=C1orf196;
//
ID   CA195_HUMAN             Reviewed;         126 AA.
AC   Q5TG92;
DE   RecName: Full=Putative uncharacterized protein C1orf195;
GN   Name=C1orf195;
//
ID   CA210_HUMAN             Reviewed;         113 AA.
AC   Q8IVY1; D3DPX2;
DE   RecName: Full=Putative uncharacterized protein C1orf210;
GN   Name=C1orf210;
//
ID   CA200_HUMAN             Reviewed;         167 AA.
AC   Q5SR53; Q8N853;
DE   RecName: Full=Putative uncharacterized protein C1orf200;
GN   Name=C1orf200;
//
ID   CA211_HUMAN             Reviewed;          96 AA.
AC   Q8N6G1;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00337;
GN   Name=LINC00337; Synonyms=C1orf211, NCRNA00337;
//
ID   CA213_HUMAN             Reviewed;         126 AA.
AC   Q8NC38; Q2VPR7;
DE   RecName: Full=Putative uncharacterized protein C1orf213;
GN   Name=C1orf213;
//
ID   CA216_HUMAN             Reviewed;         229 AA.
AC   Q8TAB5; D3DPS1; Q8N8N6;
DE   RecName: Full=UPF0500 protein C1orf216;
GN   Name=C1orf216;
//
ID   CA222_HUMAN             Reviewed;         305 AA.
AC   Q69YW0;
DE   RecName: Full=Uncharacterized protein C1orf222;
GN   Name=C1orf222;
//
ID   CA228_HUMAN             Reviewed;         440 AA.
AC   Q6PIY5; A1KXE5;
DE   RecName: Full=Uncharacterized protein C1orf228;
DE   AltName: Full=p40;
GN   Name=C1orf228; Synonyms=NCRNA00082;
//
ID   CA220_HUMAN             Reviewed;         134 AA.
AC   Q5T0J3; B2RN72; Q8NAD3;
DE   RecName: Full=Putative uncharacterized protein C1orf220;
GN   Name=C1orf220;
//
ID   CA226_HUMAN             Reviewed;         272 AA.
AC   A1L170; B4DF31;
DE   RecName: Full=Uncharacterized protein C1orf226;
GN   Name=C1orf226;
//
ID   CA233_HUMAN             Reviewed;         226 AA.
AC   F2Z333;
DE   RecName: Full=Fibronectin type-III domain-containing transmembrane protein C1orf233;
DE   Flags: Precursor;
GN   Name=C1orf233;
//
ID   CA229_HUMAN             Reviewed;         237 AA.
AC   Q6ZS94;
DE   RecName: Full=Putative uncharacterized protein C1orf229;
GN   Name=C1orf229;
//
ID   CA2D1_HUMAN             Reviewed;        1103 AA.
AC   P54289; Q17R45; Q9UD80; Q9UD81; Q9UD82;
DE   RecName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-1;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha-2/delta-1;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit alpha-2-1;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit delta-1;
DE   Flags: Precursor;
GN   Name=CACNA2D1; Synonyms=CACNL2A, CCHL2A, MHS3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IDA:BHF-UCL.
//
ID   CA234_HUMAN             Reviewed;         121 AA.
AC   H3BTG2; H3BR39;
DE   RecName: Full=Uncharacterized protein C1orf234;
DE   Flags: Precursor;
GN   Name=C1orf234;
//
ID   CA2D2_HUMAN             Reviewed;        1150 AA.
AC   Q9NY47; A7MD15; Q9NY48; Q9UEW0; Q9Y268;
DE   RecName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-2;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha-2/delta-2;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit alpha-2-2;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit delta-2;
DE   Flags: Precursor;
GN   Name=CACNA2D2; Synonyms=KIAA0558;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0060024; P:rhythmic synaptic transmission; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CA2D3_HUMAN             Reviewed;        1091 AA.
AC   Q8IZS8; B2RPL6; Q9NY16; Q9NY18;
DE   RecName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-3;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha-2/delta-3;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit alpha-2-3;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit delta-3;
DE   Flags: Precursor;
GN   Name=CACNA2D3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:Ensembl.
//
ID   CA2D4_HUMAN             Reviewed;        1137 AA.
AC   Q7Z3S7; Q7Z3S8; Q86XZ5; Q8IZS9;
DE   RecName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-4;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha-2/delta-4;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit alpha-2-4;
DE   Contains:
DE     RecName: Full=Voltage-dependent calcium channel subunit delta-4;
DE   Flags: Precursor;
GN   Name=CACNA2D4;
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
//
ID   CA5BL_HUMAN             Reviewed;         195 AA.
AC   Q8WTZ4; A6NEZ4;
DE   RecName: Full=Putative inactive carbonic anhydrase 5B-like protein;
DE   AltName: Full=CA-VB-like protein;
GN   Name=CA5BP1; Synonyms=CA5B, CA5BL;
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CAAP1_HUMAN             Reviewed;         361 AA.
AC   Q9H8G2; B4DWT4; D3DRK4; Q5VY32; Q6IPE6; Q96C59;
DE   RecName: Full=Caspase activity and apoptosis inhibitor 1;
DE   AltName: Full=Conserved anti-apoptotic protein;
DE            Short=CAAP;
GN   Name=CAAP1; Synonyms=C9orf82, CAAP;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   CAAS1_HUMAN             Reviewed;         211 AA.
AC   Q8N1I8;
DE   RecName: Full=Putative uncharacterized protein encoded by CACTIN-AS1;
DE   AltName: Full=Cactin antisense RNA 1;
GN   Name=CACTIN-AS1; Synonyms=C19orf29-AS1, C19orf29OS;
//
ID   CAB39_HUMAN             Reviewed;         341 AA.
AC   Q9Y376; A8K8L7;
DE   RecName: Full=Calcium-binding protein 39;
DE   AltName: Full=MO25alpha;
DE   AltName: Full=Protein Mo25;
GN   Name=CAB39; Synonyms=MO25; ORFNames=CGI-66;
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
//
ID   CAB45_HUMAN             Reviewed;         362 AA.
AC   Q9BRK5; B1AME5; B1AME6; B2RDF1; B4DSM1; Q53G52; Q53HQ9; Q8NBQ3;
AC   Q96AA1; Q9NZP7; Q9UN53;
DE   RecName: Full=45 kDa calcium-binding protein;
DE            Short=Cab45;
DE   AltName: Full=Stromal cell-derived factor 4;
DE            Short=SDF-4;
DE   Flags: Precursor;
GN   Name=SDF4; Synonyms=CAB45; ORFNames=PSEC0034;
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; ISS:BHF-UCL.
DR   GO; GO:0021549; P:cerebellum development; ISS:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045471; P:response to ethanol; ISS:BHF-UCL.
DR   GO; GO:0009650; P:UV protection; ISS:BHF-UCL.
DR   GO; GO:0070625; P:zymogen granule exocytosis; ISS:BHF-UCL.
//
ID   CABIN_HUMAN             Reviewed;        2220 AA.
AC   Q9Y6J0; G5E9F3; Q6PHY0; Q9Y460;
DE   RecName: Full=Calcineurin-binding protein cabin-1;
DE   AltName: Full=Calcineurin inhibitor;
DE            Short=CAIN;
GN   Name=CABIN1; Synonyms=KIAA0330;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; NAS:GOC.
//
ID   CABL1_HUMAN             Reviewed;         633 AA.
AC   Q8TDN4; B4DK60; Q8N3Y8; Q8NA22; Q9BTG1;
DE   RecName: Full=CDK5 and ABL1 enzyme substrate 1;
DE   AltName: Full=Interactor with CDK3 1;
DE            Short=Ik3-1;
GN   Name=CABLES1; Synonyms=CABLES;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
//
ID   CABL2_HUMAN             Reviewed;         478 AA.
AC   Q9BTV7; Q5JWL0; Q9BYK0;
DE   RecName: Full=CDK5 and ABL1 enzyme substrate 2;
DE   AltName: Full=Interactor with CDK3 2;
DE            Short=Ik3-2;
GN   Name=CABLES2; Synonyms=C20orf150;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
//
ID   CABP1_HUMAN             Reviewed;         370 AA.
AC   Q9NZU7; O95663; Q8N6H5; Q9NZU8;
DE   RecName: Full=Calcium-binding protein 1;
DE            Short=CaBP1;
DE   AltName: Full=Calbrain;
DE   AltName: Full=Caldendrin;
GN   Name=CABP1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0008139; F:nuclear localization sequence binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0010651; P:negative regulation of cell communication by electrical coupling; IEA:Ensembl.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:1901386; P:negative regulation of voltage-gated calcium channel activity; IEA:Ensembl.
//
ID   CABP2_HUMAN             Reviewed;         220 AA.
AC   Q9NPB3;
DE   RecName: Full=Calcium-binding protein 2;
DE            Short=CaBP2;
GN   Name=CABP2;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CABP4_HUMAN             Reviewed;         275 AA.
AC   P57796; Q8N4Z2; Q8WWY5;
DE   RecName: Full=Calcium-binding protein 4;
DE            Short=CaBP4;
GN   Name=CABP4;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0008594; P:photoreceptor cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007602; P:phototransduction; IEA:Ensembl.
DR   GO; GO:0060040; P:retinal bipolar neuron differentiation; IEA:Ensembl.
DR   GO; GO:0046549; P:retinal cone cell development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CABP7_HUMAN             Reviewed;         215 AA.
AC   Q86V35;
DE   RecName: Full=Calcium-binding protein 7;
DE            Short=CaBP7;
DE   AltName: Full=Calneuron II;
DE   AltName: Full=Calneuron-2;
GN   Name=CABP7; Synonyms=CALN2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CABP5_HUMAN             Reviewed;         173 AA.
AC   Q9NP86; A0AUY4;
DE   RecName: Full=Calcium-binding protein 5;
DE            Short=CaBP5;
GN   Name=CABP5; Synonyms=CABP3;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   CABP8_HUMAN             Reviewed;         219 AA.
AC   Q9BXU9; J3KQA7;
DE   RecName: Full=Calcium-binding protein 8;
DE            Short=CaBP8;
DE   AltName: Full=Calneuron I;
DE   AltName: Full=Calneuron-1;
GN   Name=CALN1; Synonyms=CABP8;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CABS1_HUMAN             Reviewed;         395 AA.
AC   Q96KC9; B2RCB5; Q86UE0; Q96M17;
DE   RecName: Full=Calcium-binding and spermatid-specific protein 1;
DE   AltName: Full=Testis development protein NYD-SP26;
GN   Name=CABS1; Synonyms=C4orf35;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CABYR_HUMAN             Reviewed;         493 AA.
AC   O75952; B2R857; Q8WXW5; Q9HAY3; Q9HAY4; Q9HAY5; Q9HCY9;
DE   RecName: Full=Calcium-binding tyrosine phosphorylation-regulated protein;
DE   AltName: Full=Calcium-binding protein 86;
DE   AltName: Full=Cancer/testis antigen 88;
DE            Short=CT88;
DE   AltName: Full=Fibrousheathin II;
DE   AltName: Full=Fibrousheathin-2;
DE            Short=FSP-2;
DE   AltName: Full=Testis-specific calcium-binding protein CBP86;
GN   Name=CABYR; Synonyms=CBP86, FSP2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; NAS:BHF-UCL.
DR   GO; GO:0003351; P:epithelial cilium movement; NAS:BHF-UCL.
DR   GO; GO:0048240; P:sperm capacitation; NAS:BHF-UCL.
//
ID   CAC1A_HUMAN             Reviewed;        2505 AA.
AC   O00555; J3KP41; P78510; P78511; Q16290; Q92690; Q99790; Q99791;
AC   Q99792; Q99793; Q9NS88; Q9UDC4;
DE   RecName: Full=Voltage-dependent P/Q-type calcium channel subunit alpha-1A;
DE   AltName: Full=Brain calcium channel I;
DE            Short=BI;
DE   AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 4;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.1;
GN   Name=CACNA1A; Synonyms=CACH4, CACN3, CACNL1A4;
DR   GuidetoPHARMACOLOGY; 532; -.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; IDA:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0030644; P:cellular chloride ion homeostasis; IEA:Ensembl.
DR   GO; GO:0021679; P:cerebellar molecular layer development; IEA:Ensembl.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0021590; P:cerebellum maturation; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0014051; P:gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0050883; P:musculoskeletal movement, spinal reflex action; IEA:Ensembl.
DR   GO; GO:0032353; P:negative regulation of hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0042133; P:neurotransmitter metabolic process; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
DR   GO; GO:0014056; P:regulation of acetylcholine secretion, neurotransmission; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0017158; P:regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0060024; P:rhythmic synaptic transmission; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IBA:RefGenome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0021750; P:vestibular nucleus development; IEA:Ensembl.
//
ID   CAC1B_HUMAN             Reviewed;        2339 AA.
AC   Q00975; B1AQK5;
DE   RecName: Full=Voltage-dependent N-type calcium channel subunit alpha-1B;
DE   AltName: Full=Brain calcium channel III;
DE            Short=BIII;
DE   AltName: Full=Calcium channel, L type, alpha-1 polypeptide isoform 5;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.2;
GN   Name=CACNA1B; Synonyms=CACH5, CACNL1A5;
DR   GuidetoPHARMACOLOGY; 533; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CAC1C_HUMAN             Reviewed;        2221 AA.
AC   Q13936; B2RUT3; E9PDJ0; Q13917; Q13918; Q13919; Q13920; Q13921;
AC   Q13922; Q13923; Q13924; Q13925; Q13926; Q13927; Q13928; Q13929;
AC   Q13930; Q13932; Q13933; Q14743; Q14744; Q15877; Q4VMI7; Q4VMI8;
AC   Q4VMI9; Q6PKM7; Q8N6C0; Q99025; Q99241; Q99875;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1C;
DE   AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.2;
GN   Name=CACNA1C; Synonyms=CACH2, CACN2, CACNL1A1, CCHL1A1;
DR   GuidetoPHARMACOLOGY; 529; -.
DR   GO; GO:0051393; F:alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; IPI:UniProtKB.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0035585; P:calcium-mediated signaling using extracellular calcium source; TAS:BHF-UCL.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; TAS:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0030252; P:growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0046620; P:regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0060083; P:smooth muscle contraction involved in micturition; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   CAC1D_HUMAN             Reviewed;        2161 AA.
AC   Q01668; B0FYA3; Q13916; Q13931; Q71UT1; Q9UDC3;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1D;
DE   AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 2;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.3;
GN   Name=CACNA1D; Synonyms=CACH3, CACN4, CACNL1A2, CCHL1A2;
DR   GuidetoPHARMACOLOGY; 530; -.
DR   GO; GO:0051393; F:alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0030506; F:ankyrin binding; ISS:BHF-UCL.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0086007; F:voltage-gated calcium channel activity involved in cardiac muscle cell action potential; IC:BHF-UCL.
DR   GO; GO:0086059; F:voltage-gated calcium channel activity involved SA node cell action potential; IMP:BHF-UCL.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; IC:BHF-UCL.
DR   GO; GO:0086052; P:membrane repolarization during SA node cell action potential; IMP:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:0060372; P:regulation of atrial cardiac muscle cell membrane repolarization; ISS:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:1901379; P:regulation of potassium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAC1E_HUMAN             Reviewed;        2313 AA.
AC   Q15878; B1AM12; B1AM13; B1AM14; Q14580; Q14581;
DE   RecName: Full=Voltage-dependent R-type calcium channel subunit alpha-1E;
DE   AltName: Full=Brain calcium channel II;
DE            Short=BII;
DE   AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 6;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.3;
GN   Name=CACNA1E; Synonyms=CACH6, CACNL1A6;
DR   GuidetoPHARMACOLOGY; 534; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:MGI.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0090273; P:regulation of somatostatin secretion; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IBA:RefGenome.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   CAC1G_HUMAN             Reviewed;        2377 AA.
AC   O43497; D6RA64; E7EPR0; O43498; O94770; Q19QY8; Q19QY9; Q19QZ0;
AC   Q19QZ1; Q19QZ2; Q19QZ3; Q19QZ4; Q19QZ5; Q19QZ6; Q19QZ7; Q19QZ8;
AC   Q19QZ9; Q19R00; Q19R01; Q19R02; Q19R03; Q19R04; Q19R05; Q19R06;
AC   Q19R07; Q19R08; Q19R09; Q19R10; Q19R11; Q19R12; Q19R13; Q19R15;
AC   Q19R16; Q19R17; Q19R18; Q2TAC4; Q9NYU4; Q9NYU5; Q9NYU6; Q9NYU7;
AC   Q9NYU8; Q9NYU9; Q9NYV0; Q9NYV1; Q9UHN9; Q9UHP0; Q9ULU6; Q9UNG7;
AC   Q9Y5T2; Q9Y5T3;
DE   RecName: Full=Voltage-dependent T-type calcium channel subunit alpha-1G;
DE   AltName: Full=Cav3.1c;
DE   AltName: Full=NBR13;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav3.1;
GN   Name=CACNA1G; Synonyms=KIAA1123;
DR   GuidetoPHARMACOLOGY; 535; -.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IBA:RefGenome.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0010045; P:response to nickel cation; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CAC1F_HUMAN             Reviewed;        1977 AA.
AC   O60840; A6NI29; F5CIQ9; O43901; O95226; Q9UHB1;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1F;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.4;
GN   Name=CACNA1F; Synonyms=CACNAF1;
DR   GuidetoPHARMACOLOGY; 531; -.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProtKB.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CAC1H_HUMAN             Reviewed;        2353 AA.
AC   O95180; B5ME00; F8WFD1; O95802; Q8WWI6; Q96QI6; Q96RZ9; Q9NYY4;
AC   Q9NYY5;
DE   RecName: Full=Voltage-dependent T-type calcium channel subunit alpha-1H;
DE   AltName: Full=Low-voltage-activated calcium channel alpha1 3.2 subunit;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav3.2;
GN   Name=CACNA1H;
DR   GuidetoPHARMACOLOGY; 536; -.
DR   GO; GO:0008332; F:low voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0032342; P:aldosterone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0035865; P:cellular response to potassium ion; IEP:UniProtKB.
DR   GO; GO:0034651; P:cortisol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; NAS:ProtInc.
DR   GO; GO:0007520; P:myoblast fusion; TAS:ProtInc.
DR   GO; GO:2000344; P:positive regulation of acrosome reaction; IMP:UniProtKB.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CAC1I_HUMAN             Reviewed;        2223 AA.
AC   Q9P0X4; B0QY12; B0QY13; B0QY14; O95504; Q5JZ88; Q7Z6S9; Q8NFX6;
AC   Q9NZC8; Q9UH15; Q9UH30; Q9ULU9; Q9UNE6;
DE   RecName: Full=Voltage-dependent T-type calcium channel subunit alpha-1I;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav3.3;
DE            Short=Ca(v)3.3;
GN   Name=CACNA1I; Synonyms=KIAA1120;
DR   GuidetoPHARMACOLOGY; 537; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CAC1S_HUMAN             Reviewed;        1873 AA.
AC   Q13698; A4IF51; B1ALM2; Q12896; Q13934;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1S;
DE   AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle;
DE   AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.1;
GN   Name=CACNA1S; Synonyms=CACH1, CACN1, CACNL1A3;
DR   GuidetoPHARMACOLOGY; 528; -.
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:Ensembl.
DR   GO; GO:0002074; P:extraocular skeletal muscle development; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0006936; P:muscle contraction; IMP:UniProtKB.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0043501; P:skeletal muscle adaptation; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006941; P:striated muscle contraction; IEA:Ensembl.
//
ID   CACB1_HUMAN             Reviewed;         598 AA.
AC   Q02641; A8K114; O15331; Q02639; Q02640; Q8N3X9; Q9C085; Q9UD79;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit beta-1;
DE            Short=CAB1;
DE   AltName: Full=Calcium channel voltage-dependent subunit beta 1;
GN   Name=CACNB1; Synonyms=CACNLB1;
DR   GO; GO:0008331; F:high voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006612; P:protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CACB2_HUMAN             Reviewed;         660 AA.
AC   Q08289; A6PVM5; A6PVM7; A6PVM8; O00304; Q5QJ99; Q5QJA0; Q5VVG9;
AC   Q5VVH0; Q5VWV6; Q6TME1; Q6TME2; Q6TME3; Q8WX81; Q96NZ3; Q96NZ4;
AC   Q96NZ5; Q9BWU2; Q9HD32; Q9Y340; Q9Y341;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit beta-2;
DE            Short=CAB2;
DE   AltName: Full=Calcium channel voltage-dependent subunit beta 2;
DE   AltName: Full=Lambert-Eaton myasthenic syndrome antigen B;
DE            Short=MYSB;
GN   Name=CACNB2; Synonyms=CACNLB2, MYSB;
DR   GO; GO:0005262; F:calcium channel activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0007528; P:neuromuscular junction development; TAS:ProtInc.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   CACB3_HUMAN             Reviewed;         484 AA.
AC   P54284; A8K0Z4; B7Z4Q1; B7Z973; B7ZAK8; F5GZW7; F5H2P6; F8VSG3;
AC   Q13913;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit beta-3;
DE            Short=CAB3;
DE   AltName: Full=Calcium channel voltage-dependent subunit beta 3;
GN   Name=CACNB3; Synonyms=CACNLB3;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CACB4_HUMAN             Reviewed;         520 AA.
AC   O00305; A7BJ74; A8K1Y4; B4DG40; O60515; Q6B000; Q96L40;
DE   RecName: Full=Voltage-dependent L-type calcium channel subunit beta-4;
DE            Short=CAB4;
DE   AltName: Full=Calcium channel voltage-dependent subunit beta 4;
GN   Name=CACNB4; Synonyms=CACNLB4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0046058; P:cAMP metabolic process; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR   GO; GO:0014051; P:gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0019227; P:neuronal action potential propagation; IEA:Ensembl.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:1901385; P:regulation of voltage-gated calcium channel activity; IMP:UniProtKB.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CACL1_HUMAN             Reviewed;         369 AA.
AC   Q86Y37; Q5XPL7; Q8IY11; Q8N7S4;
DE   RecName: Full=CDK2-associated and cullin domain-containing protein 1;
DE   AltName: Full=Cdk-associated cullin1;
GN   Name=CACUL1; Synonyms=C10orf46, CAC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   CACO1_HUMAN             Reviewed;         691 AA.
AC   Q9P1Z2; B3KVA8; Q6FI59; Q71RC3; Q86WF8; Q96JU3; Q9H090;
DE   RecName: Full=Calcium-binding and coiled-coil domain-containing protein 1;
DE   AltName: Full=Calphoglin;
DE   AltName: Full=Coiled-coil coactivator protein;
DE   AltName: Full=Sarcoma antigen NY-SAR-3;
GN   Name=CALCOCO1; Synonyms=KIAA1536; ORFNames=PP13275, UNQ2436/PRO4996;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:AgBase.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:AgBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:AgBase.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; ISS:HGNC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:HGNC.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CACO2_HUMAN             Reviewed;         446 AA.
AC   Q13137; B2RBT0; B4DDC4; B4DDT4; B4DP36; B4E0C0; E7ENK0; E7ETP5;
AC   E9PBE5; Q53FQ5; Q53HB5; Q6IBN9; Q9BTF7;
DE   RecName: Full=Calcium-binding and coiled-coil domain-containing protein 2;
DE   AltName: Full=Antigen nuclear dot 52 kDa protein;
DE   AltName: Full=Nuclear domain 10 protein NDP52;
DE            Short=Nuclear domain 10 protein 52;
DE   AltName: Full=Nuclear dot protein 52;
GN   Name=CALCOCO2; Synonyms=NDP52;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; TAS:ProtInc.
//
ID   CACP_HUMAN              Reviewed;         626 AA.
AC   P43155; Q5T952; Q9BW16;
DE   RecName: Full=Carnitine O-acetyltransferase;
DE            Short=Carnitine acetylase;
DE            EC=2.3.1.7;
DE   AltName: Full=Carnitine acetyltransferase;
DE            Short=CAT;
DE            Short=CrAT;
GN   Name=CRAT; Synonyms=CAT1;
DR   GO; GO:0004092; F:carnitine O-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0019254; P:carnitine metabolic process, CoA-linked; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   CAD10_HUMAN             Reviewed;         788 AA.
AC   Q9Y6N8; Q9ULB3;
DE   RecName: Full=Cadherin-10;
DE   AltName: Full=T2-cadherin;
DE   Flags: Precursor;
GN   Name=CDH10;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD11_HUMAN             Reviewed;         796 AA.
AC   P55287; A8K5D6; A8MZC8; B7WP28; Q15065; Q15066; Q9UQ93; Q9UQ94;
DE   RecName: Full=Cadherin-11;
DE   AltName: Full=OSF-4;
DE   AltName: Full=Osteoblast cadherin;
DE            Short=OB-cadherin;
DE   Flags: Precursor;
GN   Name=CDH11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0021957; P:corticospinal tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0001503; P:ossification; NAS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   CAD12_HUMAN             Reviewed;         794 AA.
AC   P55289; B2RBT1; Q86UD2;
DE   RecName: Full=Cadherin-12;
DE   AltName: Full=Brain cadherin;
DE            Short=BR-cadherin;
DE   AltName: Full=Neural type cadherin 2;
DE            Short=N-cadherin 2;
DE   Flags: Precursor;
GN   Name=CDH12;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD13_HUMAN             Reviewed;         713 AA.
AC   P55290; A8W476; A8W477; B7Z590; C9JRI6; J3KN62; Q6GTW4; Q8TBX3;
DE   RecName: Full=Cadherin-13;
DE   AltName: Full=Heart cadherin;
DE            Short=H-cadherin;
DE   AltName: Full=P105;
DE   AltName: Full=Truncated cadherin;
DE            Short=T-cad;
DE            Short=T-cadherin;
DE   Flags: Precursor;
GN   Name=CDH13; Synonyms=CDHH;
DR   GO; GO:0055100; F:adiponectin binding; ISS:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0071813; F:lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:BHF-UCL.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0043542; P:endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0043616; P:keratinocyte proliferation; IDA:BHF-UCL.
DR   GO; GO:0030032; P:lamellipodium assembly; IDA:BHF-UCL.
DR   GO; GO:0051668; P:localization within membrane; IMP:BHF-UCL.
DR   GO; GO:0055096; P:low-density lipoprotein particle mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0016601; P:Rac protein signal transduction; IMP:BHF-UCL.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0030100; P:regulation of endocytosis; IMP:BHF-UCL.
DR   GO; GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007266; P:Rho protein signal transduction; IMP:BHF-UCL.
DR   GO; GO:0002040; P:sprouting angiogenesis; IDA:BHF-UCL.
//
ID   CAD15_HUMAN             Reviewed;         814 AA.
AC   P55291;
DE   RecName: Full=Cadherin-15;
DE   AltName: Full=Cadherin-14;
DE   AltName: Full=Muscle cadherin;
DE            Short=M-cadherin;
DE   Flags: Precursor;
GN   Name=CDH15; Synonyms=CDH14, CDH3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
//
ID   CAD17_HUMAN             Reviewed;         832 AA.
AC   Q12864; Q15336; Q2M2E0;
DE   RecName: Full=Cadherin-17;
DE   AltName: Full=Intestinal peptide-associated transporter HPT-1;
DE   AltName: Full=Liver-intestine cadherin;
DE            Short=LI-cadherin;
DE   Flags: Precursor;
GN   Name=CDH17;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005427; F:proton-dependent oligopeptide secondary active transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   CAD16_HUMAN             Reviewed;         829 AA.
AC   O75309; B4DPA8; H3BPD3; Q6UW93;
DE   RecName: Full=Cadherin-16;
DE   AltName: Full=Kidney-specific cadherin;
DE            Short=Ksp-cadherin;
DE   Flags: Precursor;
GN   Name=CDH16; ORFNames=UNQ695/PRO1340;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD18_HUMAN             Reviewed;         790 AA.
AC   Q13634; A8K0I2; B4DHG6; Q8N5Z2;
DE   RecName: Full=Cadherin-18;
DE   AltName: Full=Cadherin-14;
DE   Flags: Precursor;
GN   Name=CDH18; Synonyms=CDH14;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD19_HUMAN             Reviewed;         772 AA.
AC   Q9H159; B4E1V5; F5H1K0;
DE   RecName: Full=Cadherin-19;
DE   Flags: Precursor;
GN   Name=CDH19; Synonyms=CDH7L2; ORFNames=UNQ478/PRO941;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD20_HUMAN             Reviewed;         801 AA.
AC   Q9HBT6; Q495S3;
DE   RecName: Full=Cadherin-20;
DE   Flags: Precursor;
GN   Name=CDH20; Synonyms=CDH7L3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD22_HUMAN             Reviewed;         828 AA.
AC   Q9UJ99; B9EGK7; O43205;
DE   RecName: Full=Cadherin-22;
DE   AltName: Full=Pituitary and brain cadherin;
DE            Short=PB-cadherin;
DE   Flags: Precursor;
GN   Name=CDH22; Synonyms=C20orf25;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD23_HUMAN             Reviewed;        3354 AA.
AC   Q9H251; C4IXS9; F6U049; Q5QGS1; Q5QGS2; Q5QGS5; Q5QGS6; Q5XKN2;
AC   Q6UWW1; Q96JL3; Q9H4K9;
DE   RecName: Full=Cadherin-23;
DE   AltName: Full=Otocadherin;
DE   Flags: Precursor;
GN   Name=CDH23; Synonyms=KIAA1774, KIAA1812; ORFNames=UNQ1894/PRO4340;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006816; P:calcium ion transport; IMP:DFLAT.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IMP:DFLAT.
DR   GO; GO:0050957; P:equilibrioception; IMP:HGNC.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:DFLAT.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   CAD24_HUMAN             Reviewed;         819 AA.
AC   Q86UP0; D3DS44; Q86UP1; Q9NT84;
DE   RecName: Full=Cadherin-24;
DE   Flags: Precursor;
GN   Name=CDH24; Synonyms=CDH11L; ORFNames=UNQ2834/PRO34009;
DR   GO; GO:0045294; F:alpha-catenin binding; IPI:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:MGI.
DR   GO; GO:0070097; F:delta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:MGI.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CAD26_HUMAN             Reviewed;         852 AA.
AC   Q8IXH8; A2A2M5; B3KNX3; Q6P5Y6; Q8TCH3; Q9BQN4; Q9NRU1;
DE   RecName: Full=Cadherin-like protein 26;
DE   AltName: Full=Cadherin-like protein VR20;
DE   Flags: Precursor;
GN   Name=CDH26;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CADH1_HUMAN             Reviewed;         882 AA.
AC   P12830; A8K1U7; Q13799; Q14216; Q15855; Q16194; Q4PJ14;
DE   RecName: Full=Cadherin-1;
DE   AltName: Full=CAM 120/80;
DE   AltName: Full=Epithelial cadherin;
DE            Short=E-cadherin;
DE   AltName: Full=Uvomorulin;
DE   AltName: CD_antigen=CD324;
DE   Contains:
DE     RecName: Full=E-Cad/CTF1;
DE   Contains:
DE     RecName: Full=E-Cad/CTF2;
DE   Contains:
DE     RecName: Full=E-Cad/CTF3;
DE   Flags: Precursor;
GN   Name=CDH1; Synonyms=CDHE, UVO;
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0050839; F:cell adhesion molecule binding; NAS:BHF-UCL.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProt.
DR   GO; GO:0032794; F:GTPase activating protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.
DR   GO; GO:0071285; P:cellular response to lithium ion; IDA:UniProtKB.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IMP:UniProt.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; NAS:UniProtKB.
DR   GO; GO:0060576; P:intestinal epithelial cell development; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0019538; P:protein metabolic process; IEA:Ensembl.
DR   GO; GO:0060693; P:regulation of branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:2000008; P:regulation of protein localization to cell surface; IEA:Ensembl.
DR   GO; GO:0033561; P:regulation of water loss via skin; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IEA:Ensembl.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   CADH2_HUMAN             Reviewed;         906 AA.
AC   P19022; B0YIY6; Q14923; Q8N173;
DE   RecName: Full=Cadherin-2;
DE   AltName: Full=CDw325;
DE   AltName: Full=Neural cadherin;
DE            Short=N-cadherin;
DE   AltName: CD_antigen=CD325;
DE   Flags: Precursor;
GN   Name=CDH2; Synonyms=CDHN, NCAD;
DR   GO; GO:0045294; F:alpha-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; TAS:AgBase.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
//
ID   CADH3_HUMAN             Reviewed;         829 AA.
AC   P22223; B2R6F4; Q05DI6;
DE   RecName: Full=Cadherin-3;
DE   AltName: Full=Placental cadherin;
DE            Short=P-cadherin;
DE   Flags: Precursor;
GN   Name=CDH3; Synonyms=CDHP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProt.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0022405; P:hair cycle process; IMP:UniProt.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0031424; P:keratinization; IMP:UniProt.
DR   GO; GO:0051796; P:negative regulation of catagen; IMP:UniProt.
DR   GO; GO:0032912; P:negative regulation of transforming growth factor beta2 production; IMP:UniProt.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProt.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; IMP:UniProt.
DR   GO; GO:0048023; P:positive regulation of melanin biosynthetic process; IMP:UniProt.
DR   GO; GO:0032773; P:positive regulation of monophenol monooxygenase activity; IMP:UniProt.
DR   GO; GO:0060901; P:regulation of hair cycle by canonical Wnt signaling pathway; IMP:UniProt.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IMP:UniProt.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   CADH4_HUMAN             Reviewed;         916 AA.
AC   P55283; B3KWB8; G3V1P8; Q2M208; Q5VZ44; Q9BZ05;
DE   RecName: Full=Cadherin-4;
DE   AltName: Full=Retinal cadherin;
DE            Short=R-CAD;
DE            Short=R-cadherin;
DE   Flags: Precursor;
GN   Name=CDH4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
//
ID   CADH5_HUMAN             Reviewed;         784 AA.
AC   P33151; Q4VAI5; Q4VAI6;
DE   RecName: Full=Cadherin-5;
DE   AltName: Full=7B4 antigen;
DE   AltName: Full=Vascular endothelial cadherin;
DE            Short=VE-cadherin;
DE   AltName: CD_antigen=CD144;
DE   Flags: Precursor;
GN   Name=CDH5;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0001955; P:blood vessel maturation; IEA:Ensembl.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.
//
ID   CADH6_HUMAN             Reviewed;         790 AA.
AC   P55285; A8K5H5; Q9BWS0;
DE   RecName: Full=Cadherin-6;
DE   AltName: Full=Kidney cadherin;
DE            Short=K-cadherin;
DE   Flags: Precursor;
GN   Name=CDH6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CADH7_HUMAN             Reviewed;         785 AA.
AC   Q9ULB5; Q9H157;
DE   RecName: Full=Cadherin-7;
DE   Flags: Precursor;
GN   Name=CDH7; Synonyms=CDH7L1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CADH8_HUMAN             Reviewed;         799 AA.
AC   P55286; B3KWC1; Q14DC6; Q9ULB2;
DE   RecName: Full=Cadherin-8;
DE   Flags: Precursor;
GN   Name=CDH8;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
//
ID   CADH9_HUMAN             Reviewed;         789 AA.
AC   Q9ULB4; Q3B7I5;
DE   RecName: Full=Cadherin-9;
DE   Flags: Precursor;
GN   Name=CDH9;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CADM1_HUMAN             Reviewed;         442 AA.
AC   Q9BY67; A4FVB5; F5H0J4; H0YGA7; H1ZZV9; H1ZZW1; H1ZZW2; Q86WB8;
AC   Q8N2F4;
DE   RecName: Full=Cell adhesion molecule 1;
DE   AltName: Full=Immunoglobulin superfamily member 4;
DE            Short=IgSF4;
DE   AltName: Full=Nectin-like protein 2;
DE            Short=NECL-2;
DE   AltName: Full=Spermatogenic immunoglobulin superfamily;
DE            Short=SgIgSF;
DE   AltName: Full=Synaptic cell adhesion molecule;
DE            Short=SynCAM;
DE   AltName: Full=Tumor suppressor in lung cancer 1;
DE            Short=TSLC-1;
DE   Flags: Precursor;
GN   Name=CADM1; Synonyms=IGSF4, IGSF4A, NECL2, SYNCAM, TSLC1;
DR   GO; GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008037; P:cell recognition; IDA:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0051606; P:detection of stimulus; IDA:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0042271; P:susceptibility to natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0009826; P:unidimensional cell growth; IEA:Ensembl.
//
ID   CADM2_HUMAN             Reviewed;         435 AA.
AC   Q8N3J6; Q3KQY9; Q658Q7; Q8IZP8;
DE   RecName: Full=Cell adhesion molecule 2;
DE   AltName: Full=Immunoglobulin superfamily member 4D;
DE            Short=IgSF4D;
DE   AltName: Full=Nectin-like protein 3;
DE            Short=NECL-3;
DE   AltName: Full=Synaptic cell adhesion molecule 2;
DE            Short=SynCAM 2;
DE   Flags: Precursor;
GN   Name=CADM2; Synonyms=IGSF4D, NECL3;
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
//
ID   CADM3_HUMAN             Reviewed;         398 AA.
AC   Q8N126; Q8IZQ9; Q9NVJ5; Q9UJP1;
DE   RecName: Full=Cell adhesion molecule 3;
DE   AltName: Full=Brain immunoglobulin receptor;
DE   AltName: Full=Immunoglobulin superfamily member 4B;
DE            Short=IgSF4B;
DE   AltName: Full=Nectin-like protein 1;
DE            Short=NECL-1;
DE   AltName: Full=Synaptic cell adhesion molecule 3;
DE            Short=SynCAM3;
DE   AltName: Full=TSLC1-like protein 1;
DE            Short=TSLL1;
DE   Flags: Precursor;
GN   Name=CADM3; Synonyms=IGSF4B, NECL1, SYNCAM3, TSLL1;
GN   ORFNames=UNQ225/PRO258;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:HGNC.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:HGNC.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:HGNC.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
//
ID   CADM4_HUMAN             Reviewed;         388 AA.
AC   Q8NFZ8; B2R7L5; Q9Y4A4;
DE   RecName: Full=Cell adhesion molecule 4;
DE   AltName: Full=Immunoglobulin superfamily member 4C;
DE            Short=IgSF4C;
DE   AltName: Full=Nectin-like protein 4;
DE            Short=NECL-4;
DE   AltName: Full=TSLC1-like protein 2;
DE   Flags: Precursor;
GN   Name=CADM4; Synonyms=IGSF4C, NECL4, TSLL2;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CAF17_HUMAN             Reviewed;         356 AA.
AC   Q5T440;
DE   RecName: Full=Putative transferase CAF17, mitochondrial;
DE            EC=2.1.-.-;
DE   AltName: Full=Iron-sulfur cluster assembly factor homolog;
DE   Flags: Precursor;
GN   Name=IBA57; Synonyms=C1orf69;
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006546; P:glycine catabolic process; IEA:InterPro.
DR   GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
//
ID   CAF1A_HUMAN             Reviewed;         956 AA.
AC   Q13111; Q6NXG5; Q7Z7K3; Q9UJY8;
DE   RecName: Full=Chromatin assembly factor 1 subunit A;
DE            Short=CAF-1 subunit A;
DE   AltName: Full=Chromatin assembly factor I p150 subunit;
DE            Short=CAF-I 150 kDa subunit;
DE            Short=CAF-I p150;
DE            Short=hp150;
GN   Name=CHAF1A; Synonyms=CAF, CAF1P150;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0031497; P:chromatin assembly; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CAF1B_HUMAN             Reviewed;         559 AA.
AC   Q13112; Q99548;
DE   RecName: Full=Chromatin assembly factor 1 subunit B;
DE            Short=CAF-1 subunit B;
DE   AltName: Full=Chromatin assembly factor I p60 subunit;
DE            Short=CAF-I 60 kDa subunit;
DE            Short=CAF-I p60;
DE   AltName: Full=M-phase phosphoprotein 7;
GN   Name=CHAF1B; Synonyms=CAF1A, CAF1P60, MPHOSPH7, MPP7;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0042393; F:histone binding; NAS:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0031497; P:chromatin assembly; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CAGE1_HUMAN             Reviewed;         777 AA.
AC   Q8TC20; D6RCT9; Q5TAM0; Q86TM4; Q8N7R5;
DE   RecName: Full=Cancer-associated gene 1 protein;
DE            Short=CAGE-1;
DE   AltName: Full=Cancer/testis antigen 3;
DE            Short=CT3;
GN   Name=CAGE1; Synonyms=CTAG3;
//
ID   CAH10_HUMAN             Reviewed;         328 AA.
AC   Q9NS85; B2R7J0;
DE   RecName: Full=Carbonic anhydrase-related protein 10;
DE   AltName: Full=Carbonic anhydrase-related protein X;
DE            Short=CA-RP X;
DE            Short=CARP X;
DE   AltName: Full=Cerebral protein 15;
GN   Name=CA10; ORFNames=hucep-15, UNQ533/PRO1076;
DR   GO; GO:0007420; P:brain development; NAS:UniProtKB.
//
ID   CAH11_HUMAN             Reviewed;         328 AA.
AC   O75493; O60596; Q6FHI1; Q9UEC4;
DE   RecName: Full=Carbonic anhydrase-related protein 11;
DE   AltName: Full=CA-RP XI;
DE            Short=CA-XI;
DE            Short=CARP XI;
DE   AltName: Full=Carbonic anhydrase-related protein 2;
DE            Short=CA-RP II;
DE            Short=CARP-2;
DE   Flags: Precursor;
GN   Name=CA11; Synonyms=CARP2; ORFNames=UNQ211/PRO237;
//
ID   CAH12_HUMAN             Reviewed;         354 AA.
AC   O43570; Q53YE5; Q9BWG2;
DE   RecName: Full=Carbonic anhydrase 12;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase XII;
DE   AltName: Full=Carbonic anhydrase XII;
DE            Short=CA-XII;
DE   AltName: Full=Tumor antigen HOM-RCC-3.1.3;
DE   Flags: Precursor;
GN   Name=CA12;
DR   GuidetoPHARMACOLOGY; 2747; -.
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH13_HUMAN             Reviewed;         262 AA.
AC   Q8N1Q1;
DE   RecName: Full=Carbonic anhydrase 13;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase XIII;
DE   AltName: Full=Carbonic anhydrase XIII;
DE            Short=CA-XIII;
GN   Name=CA13;
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH14_HUMAN             Reviewed;         337 AA.
AC   Q9ULX7; Q5TB24; Q8NCF4;
DE   RecName: Full=Carbonic anhydrase 14;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase XIV;
DE   AltName: Full=Carbonic anhydrase XIV;
DE            Short=CA-XIV;
DE   Flags: Precursor;
GN   Name=CA14; ORFNames=UNQ690/PRO1335;
DR   GuidetoPHARMACOLOGY; 2598; -.
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH1_HUMAN              Reviewed;         261 AA.
AC   P00915;
DE   RecName: Full=Carbonic anhydrase 1;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase I;
DE   AltName: Full=Carbonic anhydrase B;
DE            Short=CAB;
DE   AltName: Full=Carbonic anhydrase I;
DE            Short=CA-I;
GN   Name=CA1;
DR   GuidetoPHARMACOLOGY; 2597; -.
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH2_HUMAN              Reviewed;         260 AA.
AC   P00918; B2R7G8; Q6FI12; Q96ET9;
DE   RecName: Full=Carbonic anhydrase 2;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase II;
DE   AltName: Full=Carbonic anhydrase C;
DE            Short=CAC;
DE   AltName: Full=Carbonic anhydrase II;
DE            Short=CA-II;
GN   Name=CA2;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0038166; P:angiotensin-activated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0015670; P:carbon dioxide transport; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0032849; P:positive regulation of cellular pH reduction; IEA:Ensembl.
DR   GO; GO:2001150; P:positive regulation of dipeptide transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0044070; P:regulation of anion transport; IDA:UniProtKB.
DR   GO; GO:0051453; P:regulation of intracellular pH; ISS:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0046903; P:secretion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH3_HUMAN              Reviewed;         260 AA.
AC   P07451; B2R867; B3KUC8; O60842;
DE   RecName: Full=Carbonic anhydrase 3;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase III;
DE   AltName: Full=Carbonic anhydrase III;
DE            Short=CA-III;
GN   Name=CA3;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0016151; F:nickel cation binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH4_HUMAN              Reviewed;         312 AA.
AC   P22748; Q6FHI7;
DE   RecName: Full=Carbonic anhydrase 4;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase IV;
DE   AltName: Full=Carbonic anhydrase IV;
DE            Short=CA-IV;
DE   Flags: Precursor;
GN   Name=CA4;
DR   GuidetoPHARMACOLOGY; 2599; -.
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:DFLAT.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; IMP:DFLAT.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0048513; P:organ development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH5A_HUMAN             Reviewed;         305 AA.
AC   P35218; B2RPF2;
DE   RecName: Full=Carbonic anhydrase 5A, mitochondrial;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase VA;
DE   AltName: Full=Carbonic anhydrase VA;
DE            Short=CA-VA;
DE   Flags: Precursor;
GN   Name=CA5A; Synonyms=CA5;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH5B_HUMAN             Reviewed;         317 AA.
AC   Q9Y2D0; A8K4T5;
DE   RecName: Full=Carbonic anhydrase 5B, mitochondrial;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase VB;
DE   AltName: Full=Carbonic anhydrase VB;
DE            Short=CA-VB;
DE   Flags: Precursor;
GN   Name=CA5B;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH6_HUMAN              Reviewed;         308 AA.
AC   P23280; E7EMQ1; Q5FBW3; Q5FC00; Q96QX8; Q9UF03;
DE   RecName: Full=Carbonic anhydrase 6;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase VI;
DE   AltName: Full=Carbonic anhydrase VI;
DE            Short=CA-VI;
DE   AltName: Full=Salivary carbonic anhydrase;
DE   AltName: Full=Secreted carbonic anhydrase;
DE   Flags: Precursor;
GN   Name=CA6;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH7_HUMAN              Reviewed;         264 AA.
AC   P43166; Q541F0; Q86YU0;
DE   RecName: Full=Carbonic anhydrase 7;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase VII;
DE   AltName: Full=Carbonic anhydrase VII;
DE            Short=CA-VII;
GN   Name=CA7;
DR   GuidetoPHARMACOLOGY; 2749; -.
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAH8_HUMAN              Reviewed;         290 AA.
AC   P35219; A8K0A5; B3KQZ7; Q32MY2;
DE   RecName: Full=Carbonic anhydrase-related protein;
DE            Short=CARP;
DE   AltName: Full=Carbonic anhydrase VIII;
DE            Short=CA-VIII;
GN   Name=CA8; Synonyms=CALS;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:Ensembl.
//
ID   CAH9_HUMAN              Reviewed;         459 AA.
AC   Q16790; Q5T4R1;
DE   RecName: Full=Carbonic anhydrase 9;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase IX;
DE   AltName: Full=Carbonic anhydrase IX;
DE            Short=CA-IX;
DE            Short=CAIX;
DE   AltName: Full=Membrane antigen MN;
DE   AltName: Full=P54/58N;
DE   AltName: Full=Renal cell carcinoma-associated antigen G250;
DE            Short=RCC-associated antigen G250;
DE   AltName: Full=pMW1;
DE   Flags: Precursor;
GN   Name=CA9; Synonyms=G250, MN;
DR   GO; GO:0004089; F:carbonate dehydratase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0046903; P:secretion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CAHD1_HUMAN             Reviewed;        1274 AA.
AC   Q5VU97; Q49AE9; Q658T4; Q7Z3P2; Q9H7W4; Q9H9W3; Q9HCJ9;
DE   RecName: Full=VWFA and cache domain-containing protein 1;
DE            Short=Cache domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=CACHD1; Synonyms=KIAA1573, VWCD1;
DR   GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
//
ID   CAHM1_HUMAN             Reviewed;         346 AA.
AC   Q8IU99; Q5W091;
DE   RecName: Full=Calcium homeostasis modulator protein 1;
DE   AltName: Full=Protein FAM26C;
GN   Name=CALHM1; Synonyms=FAM26C;
DR   GO; GO:0005227; F:calcium activated cation channel activity; IDA:UniProtKB.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IDA:UniProtKB.
DR   GO; GO:0015867; P:ATP transport; ISS:UniProtKB.
DR   GO; GO:0006812; P:cation transport; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0050913; P:sensory perception of bitter taste; ISS:UniProtKB.
DR   GO; GO:0050916; P:sensory perception of sweet taste; ISS:UniProtKB.
DR   GO; GO:0050917; P:sensory perception of umami taste; ISS:UniProtKB.
//
ID   CAHM2_HUMAN             Reviewed;         323 AA.
AC   Q9HA72; D3DR94; O95893; Q6ZUV9;
DE   RecName: Full=Calcium homeostasis modulator protein 2;
DE   AltName: Full=Protein FAM26B;
GN   Name=CALHM2; Synonyms=FAM26B;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   CAHM3_HUMAN             Reviewed;         350 AA.
AC   Q86XJ0; Q5W090; Q8IXR2;
DE   RecName: Full=Calcium homeostasis modulator protein 3;
DE   AltName: Full=Protein FAM26A;
GN   Name=CALHM3; Synonyms=FAM26A;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   CALB1_HUMAN             Reviewed;         261 AA.
AC   P05937; B2R696;
DE   RecName: Full=Calbindin;
DE   AltName: Full=Calbindin D28;
DE   AltName: Full=D-28K;
DE   AltName: Full=Vitamin D-dependent calcium-binding protein, avian-type;
GN   Name=CALB1; Synonyms=CAB27;
DR   GO; GO:0005509; F:calcium ion binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005499; F:vitamin D binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IMP:UniProt.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IMP:UniProt.
DR   GO; GO:0072205; P:metanephric collecting duct development; IEA:Ensembl.
DR   GO; GO:0072286; P:metanephric connecting tubule development; IEA:Ensembl.
DR   GO; GO:0072221; P:metanephric distal convoluted tubule development; IEA:Ensembl.
DR   GO; GO:0035502; P:metanephric part of ureteric bud development; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0010842; P:retina layer formation; IEA:Ensembl.
DR   GO; GO:0007614; P:short-term memory; IMP:UniProt.
//
ID   CALB2_HUMAN             Reviewed;         271 AA.
AC   P22676; A8K4Y1; Q53HD2; Q96BK4;
DE   RecName: Full=Calretinin;
DE            Short=CR;
DE   AltName: Full=29 kDa calbindin;
GN   Name=CALB2; Synonyms=CAB29;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Ensembl.
//
ID   CALCA_HUMAN             Reviewed;         128 AA.
AC   P06881; Q93048; Q9UCP0;
DE   RecName: Full=Calcitonin gene-related peptide 1;
DE   AltName: Full=Alpha-type CGRP;
DE   AltName: Full=Calcitonin gene-related peptide I;
DE            Short=CGRP-I;
DE   Flags: Precursor;
GN   Name=CALCA; Synonyms=CALC1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0001935; P:endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IDA:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IDA:MGI.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IDA:UniProtKB.
DR   GO; GO:0010523; P:negative regulation of calcium ion transport into cytosol; IDA:UniProtKB.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0001976; P:neurological system process involved in regulation of systemic arterial blood pressure; IDA:MGI.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032730; P:positive regulation of interleukin-1 alpha production; IDA:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:UniProtKB.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.
DR   GO; GO:0001944; P:vasculature development; IDA:UniProtKB.
//
ID   CALCB_HUMAN             Reviewed;         127 AA.
AC   P10092; A8K573; D3DQX4; Q569I0; Q9UCN9;
DE   RecName: Full=Calcitonin gene-related peptide 2;
DE   AltName: Full=Beta-type CGRP;
DE            Short=Beta-CGRP;
DE   AltName: Full=Calcitonin gene-related peptide II;
DE            Short=CGRP-II;
DE   Flags: Precursor;
GN   Name=CALCB; Synonyms=CALC2;
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CALCR_HUMAN             Reviewed;         508 AA.
AC   P30988; F5H605; O14585; Q13941; Q5ZGL8; Q659U6; Q6DJU8; Q6T712;
DE   RecName: Full=Calcitonin receptor;
DE            Short=CT-R;
DE   Flags: Precursor;
GN   Name=CALCR;
DR   GuidetoPHARMACOLOGY; 43; -.
DR   GO; GO:0032841; F:calcitonin binding; IDA:UniProtKB.
DR   GO; GO:0004948; F:calcitonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:GOC.
DR   GO; GO:0045762; P:positive regulation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IDA:UniProtKB.
//
ID   CALC_HUMAN              Reviewed;         141 AA.
AC   P01258; B7ZL39; Q13935; Q13937; Q52LX7;
DE   RecName: Full=Calcitonin;
DE   Contains:
DE     RecName: Full=Calcitonin;
DE   Contains:
DE     RecName: Full=Katacalcin;
DE     AltName: Full=Calcitonin carboxyl-terminal peptide;
DE              Short=CCP;
DE     AltName: Full=PDN-21;
DE   Flags: Precursor;
GN   Name=CALCA; Synonyms=CALC1;
DR   GO; GO:0031716; F:calcitonin receptor binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IDA:UniProtKB.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IDA:UniProtKB.
DR   GO; GO:0031645; P:negative regulation of neurological system process; IEA:Ensembl.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
DR   GO; GO:0045986; P:negative regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:Ensembl.
DR   GO; GO:0045762; P:positive regulation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0001984; P:vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure; IEA:Ensembl.
//
ID   CALD1_HUMAN             Reviewed;         793 AA.
AC   Q05682; A8K0X1; Q13978; Q13979; Q14741; Q14742; Q9UD91;
DE   RecName: Full=Caldesmon;
DE            Short=CDM;
GN   Name=CALD1; Synonyms=CAD, CDM;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005523; F:tropomyosin binding; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
//
ID   CALI_HUMAN              Reviewed;         588 AA.
AC   Q13939; Q9BXG7;
DE   RecName: Full=Calicin;
GN   Name=CCIN;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CALL3_HUMAN             Reviewed;         149 AA.
AC   P27482; B2R9V6; Q5SQI4;
DE   RecName: Full=Calmodulin-like protein 3;
DE   AltName: Full=CaM-like protein;
DE            Short=CLP;
DE   AltName: Full=Calmodulin-related protein NB-1;
GN   Name=CALML3;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CALL4_HUMAN             Reviewed;         196 AA.
AC   Q96GE6; B4DL15; F8W6Y4; Q6N048; Q9H286;
DE   RecName: Full=Calmodulin-like protein 4;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-20;
GN   Name=CALML4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CALL5_HUMAN             Reviewed;         146 AA.
AC   Q9NZT1; Q5SQI3; Q8IXU8;
DE   RecName: Full=Calmodulin-like protein 5;
DE   AltName: Full=Calmodulin-like skin protein;
GN   Name=CALML5; Synonyms=CLSP;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CALL6_HUMAN             Reviewed;         181 AA.
AC   Q8TD86; A2A2M3; Q6Q2C4;
DE   RecName: Full=Calmodulin-like protein 6;
DE   AltName: Full=Calglandulin-like protein;
GN   Name=CALML6; Synonyms=CAGLP, CALGP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CALM_HUMAN              Reviewed;         149 AA.
AC   P62158; P02593; P70667; P99014; Q13942; Q53S29; Q61379; Q61380;
AC   Q96HK3;
DE   RecName: Full=Calmodulin;
DE            Short=CaM;
GN   Name=CALM1; Synonyms=CALM, CAM, CAM1;
GN   and
GN   Name=CALM2; Synonyms=CAM2, CAMB;
GN   and
GN   Name=CALM3; Synonyms=CALML2, CAM3, CAMC, CAMIII;
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0031997; F:N-terminal myristoylation domain binding; IPI:UniProtKB.
DR   GO; GO:0030235; F:nitric-oxide synthase regulator activity; IEA:Ensembl.
DR   GO; GO:0043274; F:phospholipase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0072542; F:protein phosphatase activator activity; IDA:BHF-UCL.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0005513; P:detection of calcium ion; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030801; P:positive regulation of cyclic nucleotide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051343; P:positive regulation of cyclic-nucleotide phosphodiesterase activity; IDA:BHF-UCL.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IC:BHF-UCL.
DR   GO; GO:1901844; P:regulation of cell communication by electrical coupling involved in cardiac conduction; IC:BHF-UCL.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:1901841; P:regulation of high voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   CALR3_HUMAN             Reviewed;         384 AA.
AC   Q96L12; D9N574; Q96LN3;
DE   RecName: Full=Calreticulin-3;
DE   AltName: Full=Calreticulin-2;
DE   AltName: Full=Calsperin;
DE   Flags: Precursor;
GN   Name=CALR3; Synonyms=CRT2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CALRL_HUMAN             Reviewed;         461 AA.
AC   Q16602; A8K6G5; A8KAD3; Q53S02; Q53TS5;
DE   RecName: Full=Calcitonin gene-related peptide type 1 receptor;
DE            Short=CGRP type 1 receptor;
DE   AltName: Full=Calcitonin receptor-like receptor;
DE   Flags: Precursor;
GN   Name=CALCRL; Synonyms=CGRPR;
DR   GO; GO:0001605; F:adrenomedullin receptor activity; IDA:UniProtKB.
DR   GO; GO:0001635; F:calcitonin gene-related polypeptide receptor activity; IEA:Ensembl.
DR   GO; GO:0004948; F:calcitonin receptor activity; IEA:Ensembl.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0071329; P:cellular response to sucrose stimulus; IDA:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:Ensembl.
//
ID   CALR_HUMAN              Reviewed;         417 AA.
AC   P27797; Q6IAT4; Q9UDG2;
DE   RecName: Full=Calreticulin;
DE   AltName: Full=CRP55;
DE   AltName: Full=Calregulin;
DE   AltName: Full=Endoplasmic reticulum resident protein 60;
DE            Short=ERp60;
DE   AltName: Full=HACBP;
DE   AltName: Full=grp60;
DE   Flags: Precursor;
GN   Name=CALR; Synonyms=CRTC;
DR   GO; GO:0050681; F:androgen receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; TAS:BHF-UCL.
DR   GO; GO:0051087; F:chaperone binding; TAS:BHF-UCL.
DR   GO; GO:0001849; F:complement component C1q binding; TAS:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:Ensembl.
DR   GO; GO:0003729; F:mRNA binding; IDA:BHF-UCL.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044183; F:protein binding involved in protein folding; TAS:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:BHF-UCL.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IGI:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0090398; P:cellular senescence; IGI:BHF-UCL.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IEA:Ensembl.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0042921; P:glucocorticoid receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0033144; P:negative regulation of intracellular steroid hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IDA:BHF-UCL.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:BHF-UCL.
DR   GO; GO:0002502; P:peptide antigen assembly with MHC class I protein complex; ISS:BHF-UCL.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IGI:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.
DR   GO; GO:2000510; P:positive regulation of dendritic cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IGI:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; ISS:BHF-UCL.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:BHF-UCL.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
DR   GO; GO:0022417; P:protein maturation by protein folding; TAS:BHF-UCL.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0040020; P:regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0051208; P:sequestering of calcium ion; TAS:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CALU_HUMAN              Reviewed;         315 AA.
AC   O43852; B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53;
AC   D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879;
AC   O60456; Q6FHB9; Q96RL3; Q9NR43;
DE   RecName: Full=Calumenin;
DE   AltName: Full=Crocalbin;
DE   AltName: Full=IEF SSP 9302;
DE   Flags: Precursor;
GN   Name=CALU;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   CALX_HUMAN              Reviewed;         592 AA.
AC   P27824; B2R5V8; D3DWQ3;
DE   RecName: Full=Calnexin;
DE   AltName: Full=IP90;
DE   AltName: Full=Major histocompatibility complex class I antigen-binding protein p88;
DE   AltName: Full=p90;
DE   Flags: Precursor;
GN   Name=CANX;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IEA:Ensembl.
DR   GO; GO:0072583; P:clathrin-mediated endocytosis; ISS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0009306; P:protein secretion; TAS:ProtInc.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
//
ID   CALY_HUMAN              Reviewed;         217 AA.
AC   Q9NYX4; Q5VWX3; Q5VWY5; Q5VWY6;
DE   RecName: Full=Neuron-specific vesicular protein calcyon;
GN   Name=CALY; Synonyms=DRD1IP;
DR   GO; GO:0032051; F:clathrin light chain binding; IDA:UniProtKB.
DR   GO; GO:0048268; P:clathrin coat assembly; IDA:UniProtKB.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IMP:UniProtKB.
//
ID   CAMKV_HUMAN             Reviewed;         501 AA.
AC   Q8NCB2; A6NFD4; Q6FIB8; Q8NBS8; Q8NC85; Q8NDU4; Q8WTT8; Q9BQC9;
AC   Q9H0Q5;
DE   RecName: Full=CaM kinase-like vesicle-associated protein;
GN   Name=CAMKV;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
//
ID   CAMLG_HUMAN             Reviewed;         296 AA.
AC   P49069; A1L3Y3;
DE   RecName: Full=Calcium signal-modulating cyclophilin ligand;
DE            Short=CAML;
GN   Name=CAMLG; Synonyms=CAML;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001881; P:receptor recycling; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CAMP1_HUMAN             Reviewed;        1602 AA.
AC   Q5T5Y3; A1L4L2; B2REB2; B2REB3; Q70W33; Q8NCY0; Q96E80; Q96FM3;
AC   Q9UFJ5;
DE   RecName: Full=Calmodulin-regulated spectrin-associated protein 1;
GN   Name=CAMSAP1;
DR   GO; GO:0005516; F:calmodulin binding; ISS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   CAMP2_HUMAN             Reviewed;        1489 AA.
AC   Q08AD1; B1APG6; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4;
DE   RecName: Full=Calmodulin-regulated spectrin-associated protein 2;
DE   AltName: Full=Calmodulin-regulated spectrin-associated protein 1-like protein 1;
GN   Name=CAMSAP2; Synonyms=CAMSAP1L1, KIAA1078;
DR   GO; GO:0051011; F:microtubule minus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0033043; P:regulation of organelle organization; IMP:UniProtKB.
//
ID   CAMP3_HUMAN             Reviewed;        1249 AA.
AC   Q9P1Y5; Q8NDF1;
DE   RecName: Full=Calmodulin-regulated spectrin-associated protein 3;
DE   AltName: Full=Protein Nezha;
GN   Name=CAMSAP3; Synonyms=KIAA1543;
DR   GO; GO:0051011; F:microtubule minus-end binding; IDA:UniProtKB.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; IMP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0033043; P:regulation of organelle organization; IMP:UniProtKB.
DR   GO; GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB.
//
ID   CAMP_HUMAN              Reviewed;         170 AA.
AC   P49913; Q71SN9;
DE   RecName: Full=Cathelicidin antimicrobial peptide;
DE   AltName: Full=18 kDa cationic antimicrobial protein;
DE            Short=CAP-18;
DE            Short=hCAP-18;
DE   Contains:
DE     RecName: Full=Antibacterial protein FALL-39;
DE     AltName: Full=FALL-39 peptide antibiotic;
DE   Contains:
DE     RecName: Full=Antibacterial protein LL-37;
DE   Flags: Precursor;
GN   Name=CAMP; Synonyms=CAP18, FALL39; ORFNames=HSD26;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:ProtInc.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0051873; P:killing by host of symbiont cells; IDA:MGI.
DR   GO; GO:0044140; P:negative regulation of growth of symbiont on or near host surface; IDA:MGI.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
//
ID   CAN10_HUMAN             Reviewed;         672 AA.
AC   Q9HC96; A8MVS7; Q4ZFV1; Q8NCD4; Q96IG4; Q96JI2; Q9HC89; Q9HC90;
AC   Q9HC91; Q9HC92; Q9HC93; Q9HC94; Q9HC95;
DE   RecName: Full=Calpain-10;
DE            EC=3.4.22.-;
DE   AltName: Full=Calcium-activated neutral proteinase 10;
DE            Short=CANP 10;
GN   Name=CAPN10; Synonyms=KIAA1845;
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IMP:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; ISS:BHF-UCL.
DR   GO; GO:0000149; F:SNARE binding; ISS:BHF-UCL.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:BHF-UCL.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; IC:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0032388; P:positive regulation of intracellular transport; ISS:BHF-UCL.
DR   GO; GO:2000676; P:positive regulation of type B pancreatic cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IMP:BHF-UCL.
DR   GO; GO:0097050; P:type B pancreatic cell apoptotic process; IDA:BHF-UCL.
//
ID   CAN11_HUMAN             Reviewed;         739 AA.
AC   Q9UMQ6; B2RA64; Q5T3G1; Q8N4R5;
DE   RecName: Full=Calpain-11;
DE            EC=3.4.22.-;
DE   AltName: Full=Calcium-activated neutral proteinase 11;
DE            Short=CANP 11;
GN   Name=CAPN11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CAN12_HUMAN             Reviewed;         719 AA.
AC   Q6ZSI9;
DE   RecName: Full=Calpain-12;
DE            EC=3.4.22.-;
DE   AltName: Full=Calcium-activated neutral proteinase 12;
DE            Short=CANP 12;
GN   Name=CAPN12;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CAN13_HUMAN             Reviewed;         669 AA.
AC   Q6MZZ7; Q17RF0; Q580X1; Q8TE80;
DE   RecName: Full=Calpain-13;
DE            EC=3.4.22.-;
DE   AltName: Full=Calcium-activated neutral proteinase 13;
DE            Short=CANP 13;
GN   Name=CAPN13;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CAN14_HUMAN             Reviewed;         684 AA.
AC   A8MX76; B3KRU9;
DE   RecName: Full=Calpain-14;
DE            EC=3.4.22.-;
DE   AltName: Full=Calcium-activated neutral proteinase 14;
DE            Short=CANP 14;
GN   Name=CAPN14;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CAN15_HUMAN             Reviewed;        1086 AA.
AC   O75808; B1B1M4; Q2KHS2; Q8WTY9; Q9BUW0;
DE   RecName: Full=Calpain-15;
DE            EC=3.4.22.-;
DE   AltName: Full=Small optic lobes homolog;
GN   Name=CAPN15; Synonyms=SOLH;
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
//
ID   CAN1_HUMAN              Reviewed;         714 AA.
AC   P07384; Q2TTR0; Q6DHV4;
DE   RecName: Full=Calpain-1 catalytic subunit;
DE            EC=3.4.22.52;
DE   AltName: Full=Calcium-activated neutral proteinase 1;
DE            Short=CANP 1;
DE   AltName: Full=Calpain mu-type;
DE   AltName: Full=Calpain-1 large subunit;
DE   AltName: Full=Cell proliferation-inducing gene 30 protein;
DE   AltName: Full=Micromolar-calpain;
DE            Short=muCANP;
GN   Name=CAPN1; Synonyms=CANPL1; ORFNames=PIG30;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
DR   GO; GO:0032801; P:receptor catabolic process; IEA:Ensembl.
//
ID   CAN2_HUMAN              Reviewed;         700 AA.
AC   P17655; A6NDG7; B7ZA96; E7ES58; Q16738; Q6PJT3; Q8WU26; Q9HBB1;
DE   RecName: Full=Calpain-2 catalytic subunit;
DE            EC=3.4.22.53;
DE   AltName: Full=Calcium-activated neutral proteinase 2;
DE            Short=CANP 2;
DE   AltName: Full=Calpain M-type;
DE   AltName: Full=Calpain large polypeptide L2;
DE   AltName: Full=Calpain-2 large subunit;
DE   AltName: Full=Millimolar-calpain;
DE            Short=M-calpain;
DE   Flags: Precursor;
GN   Name=CAPN2; Synonyms=CANPL2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0008092; F:cytoskeletal protein binding; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0016540; P:protein autoprocessing; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IC:BHF-UCL.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; TAS:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   CAN3_HUMAN              Reviewed;         821 AA.
AC   P20807; A6H8K6; Q7L4R0; Q9BQC8; Q9BTU4; Q9Y5S6; Q9Y5S7;
DE   RecName: Full=Calpain-3;
DE            EC=3.4.22.54;
DE   AltName: Full=Calcium-activated neutral proteinase 3;
DE            Short=CANP 3;
DE   AltName: Full=Calpain L3;
DE   AltName: Full=Calpain p94;
DE   AltName: Full=Muscle-specific calcium-activated neutral protease 3;
DE   AltName: Full=New calpain 1;
DE            Short=nCL-1;
GN   Name=CAPN3; Synonyms=CANP3, CANPL3, NCL1;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IDA:UniProtKB.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0055103; F:ligase regulator activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032947; F:protein complex scaffold; ISS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0031402; F:sodium ion binding; ISS:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; ISS:UniProtKB.
DR   GO; GO:0031432; F:titin binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0001896; P:autolysis; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0071472; P:cellular response to salt stress; ISS:UniProtKB.
DR   GO; GO:0070315; P:G1 to G0 transition involved in cell differentiation; IEA:Ensembl.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; TAS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; TAS:UniProtKB.
DR   GO; GO:0061061; P:muscle structure development; ISS:UniProtKB.
DR   GO; GO:0030239; P:myofibril assembly; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0033234; P:negative regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0014718; P:positive regulation of satellite cell activation involved in skeletal muscle regeneration; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; ISS:UniProtKB.
DR   GO; GO:0072657; P:protein localization to membrane; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045661; P:regulation of myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0014850; P:response to muscle activity; ISS:UniProtKB.
DR   GO; GO:0045214; P:sarcomere organization; ISS:UniProtKB.
DR   GO; GO:0097264; P:self proteolysis; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   CAN5_HUMAN              Reviewed;         640 AA.
AC   O15484; O00263;
DE   RecName: Full=Calpain-5;
DE            EC=3.4.22.-;
DE   AltName: Full=Calpain htra-3;
DE   AltName: Full=New calpain 3;
DE            Short=nCL-3;
GN   Name=CAPN5; Synonyms=NCL3;
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CAN6_HUMAN              Reviewed;         641 AA.
AC   Q9Y6Q1; D3DUY7; Q9UEQ1; Q9UJA8;
DE   RecName: Full=Calpain-6;
DE   AltName: Full=Calpain-like protease X-linked;
DE   AltName: Full=Calpamodulin;
DE            Short=CalpM;
GN   Name=CAPN6; Synonyms=CALPM, CANPX;
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
//
ID   CAN7_HUMAN              Reviewed;         813 AA.
AC   Q9Y6W3;
DE   RecName: Full=Calpain-7;
DE            EC=3.4.22.-;
DE   AltName: Full=PalB homolog;
DE            Short=PalBH;
GN   Name=CAPN7; Synonyms=PALBH;
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProt.
DR   GO; GO:0090541; F:MIT domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProt.
DR   GO; GO:0097264; P:self proteolysis; IDA:UniProtKB.
//
ID   CAN8_HUMAN              Reviewed;         703 AA.
AC   A6NHC0; B2RXL2;
DE   RecName: Full=Calpain-8;
DE            EC=3.4.22.53;
DE   AltName: Full=New calpain 2;
DE            Short=nCL-2;
DE   AltName: Full=Stomach-specific M-type calpain;
GN   Name=CAPN8; Synonyms=NCL2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CAN9_HUMAN              Reviewed;         690 AA.
AC   O14815; B1APS1; B1AQI0; Q9NS74;
DE   RecName: Full=Calpain-9;
DE            EC=3.4.22.-;
DE   AltName: Full=Digestive tract-specific calpain;
DE   AltName: Full=New calpain 4;
DE            Short=nCL-4;
DE   AltName: Full=Protein CG36;
GN   Name=CAPN9; Synonyms=NCL4;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CANB1_HUMAN             Reviewed;         170 AA.
AC   P63098; B2RC10; B5MDU4; P06705; P15117; Q08044; Q53SL0;
DE   RecName: Full=Calcineurin subunit B type 1;
DE   AltName: Full=Protein phosphatase 2B regulatory subunit 1;
DE   AltName: Full=Protein phosphatase 3 regulatory subunit B alpha isoform 1;
GN   Name=PPP3R1; Synonyms=CNA2, CNB;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; NAS:GOC.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
//
ID   CANB2_HUMAN             Reviewed;         170 AA.
AC   Q96LZ3; Q5VTR4; Q7Z4V8; Q8WYJ4;
DE   RecName: Full=Calcineurin subunit B type 2;
DE   AltName: Full=Calcineurin B-like protein;
DE            Short=CBLP;
DE   AltName: Full=Calcineurin BII;
DE            Short=CNBII;
DE   AltName: Full=PPP3R1-like;
DE   AltName: Full=Protein phosphatase 2B regulatory subunit 2;
DE   AltName: Full=Protein phosphatase 3 regulatory subunit B beta isoform;
GN   Name=PPP3R2; Synonyms=CBLP, PPP3RL;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CAND1_HUMAN             Reviewed;        1230 AA.
AC   Q86VP6; B2RAU3; O94918; Q6PIY4; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4;
AC   Q9H0G2; Q9P0H7; Q9UF85;
DE   RecName: Full=Cullin-associated NEDD8-dissociated protein 1;
DE   AltName: Full=Cullin-associated and neddylation-dissociated protein 1;
DE   AltName: Full=TBP-interacting protein of 120 kDa A;
DE            Short=TBP-interacting protein 120A;
DE   AltName: Full=p120 CAND1;
GN   Name=CAND1; Synonyms=KIAA0829, TIP120, TIP120A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010265; P:SCF complex assembly; IDA:UniProtKB.
//
ID   CAND2_HUMAN             Reviewed;        1236 AA.
AC   O75155; B9EGM9; E9KL24;
DE   RecName: Full=Cullin-associated NEDD8-dissociated protein 2;
DE   AltName: Full=Cullin-associated and neddylation-dissociated protein 2;
DE   AltName: Full=Epididymis tissue protein Li 169;
DE   AltName: Full=TBP-interacting protein of 120 kDa B;
DE            Short=TBP-interacting protein 120B;
DE   AltName: Full=p120 CAND2;
GN   Name=CAND2; Synonyms=KIAA0667, TIP120B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CANT1_HUMAN             Reviewed;         401 AA.
AC   Q8WVQ1; B4DJ54; Q7Z2J7; Q8NG05; Q8NHP0; Q9BSD5;
DE   RecName: Full=Soluble calcium-activated nucleotidase 1;
DE            Short=SCAN-1;
DE            EC=3.6.1.6;
DE   AltName: Full=Apyrase homolog;
DE   AltName: Full=Putative MAPK-activating protein PM09;
DE   AltName: Full=Putative NF-kappa-B-activating protein 107;
GN   Name=CANT1; Synonyms=SHAPY;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0045134; F:uridine-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   CAP1_HUMAN              Reviewed;         475 AA.
AC   Q01518; Q53HR7; Q5T0S1; Q5T0S2; Q6I9U6;
DE   RecName: Full=Adenylyl cyclase-associated protein 1;
DE            Short=CAP 1;
GN   Name=CAP1; Synonyms=CAP;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0001667; P:ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CAP2_HUMAN              Reviewed;         477 AA.
AC   P40123; B2R5Y3; Q6IAY2;
DE   RecName: Full=Adenylyl cyclase-associated protein 2;
DE            Short=CAP 2;
GN   Name=CAP2;
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CAP7_HUMAN              Reviewed;         251 AA.
AC   P20160; P80014; Q52LG4; Q9UCM1; Q9UCT5;
DE   RecName: Full=Azurocidin;
DE   AltName: Full=Cationic antimicrobial protein CAP37;
DE   AltName: Full=Heparin-binding protein;
DE            Short=HBP;
DE   Flags: Precursor;
GN   Name=AZU1;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; NAS:UniProtKB.
DR   GO; GO:0015643; F:toxic substance binding; NAS:UniProtKB.
DR   GO; GO:0045123; P:cellular extravasation; NAS:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; TAS:UniProtKB.
DR   GO; GO:0008347; P:glial cell migration; IDA:UniProtKB.
DR   GO; GO:0050930; P:induction of positive chemotaxis; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0048246; P:macrophage chemotaxis; NAS:UniProtKB.
DR   GO; GO:0001774; P:microglial cell activation; IEP:UniProtKB.
DR   GO; GO:0042117; P:monocyte activation; TAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050754; P:positive regulation of fractalkine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050725; P:positive regulation of interleukin-1 beta biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IEP:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0043114; P:regulation of vascular permeability; NAS:UniProtKB.
//
ID   CAPG_HUMAN              Reviewed;         348 AA.
AC   P40121; B8ZZS7; D6W5K8; Q53SA7;
DE   RecName: Full=Macrophage-capping protein;
DE   AltName: Full=Actin regulatory protein CAP-G;
GN   Name=CAPG; Synonyms=AFCP, MCP;
DR   GO; GO:0051016; P:barbed-end actin filament capping; TAS:ProtInc.
DR   GO; GO:0030031; P:cell projection assembly; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; NAS:ProtInc.
//
ID   CAPON_HUMAN             Reviewed;         506 AA.
AC   O75052; B7ZLF5; O43564; Q3T551; Q5VU95;
DE   RecName: Full=Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein;
DE   AltName: Full=C-terminal PDZ ligand of neuronal nitric oxide synthase protein;
DE   AltName: Full=Nitric oxide synthase 1 adaptor protein;
GN   Name=NOS1AP; Synonyms=CAPON, KIAA0464;
DR   GO; GO:0050998; F:nitric-oxide synthase binding; ISS:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:DFLAT.
DR   GO; GO:0045428; P:regulation of nitric oxide biosynthetic process; NAS:DFLAT.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; NAS:DFLAT.
//
ID   CAPR1_HUMAN             Reviewed;         709 AA.
AC   Q14444; A6NMY7; D3DR06; Q15074; Q6IMN4; Q6IMN7; Q9BV09;
DE   RecName: Full=Caprin-1;
DE   AltName: Full=Cell cycle-associated protein 1;
DE   AltName: Full=Cytoplasmic activation- and proliferation-associated protein 1;
DE   AltName: Full=GPI-anchored membrane protein 1;
DE   AltName: Full=GPI-anchored protein p137;
DE            Short=GPI-p137;
DE            Short=p137GPI;
DE   AltName: Full=Membrane component chromosome 11 surface marker 1;
DE   AltName: Full=RNA granule protein 105;
GN   Name=CAPRIN1; Synonyms=GPIAP1, GPIP137, M11S1, RNG105;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:UniProtKB.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.
//
ID   CAPR2_HUMAN             Reviewed;        1127 AA.
AC   Q6IMN6; E4NKG2; Q149P6; Q149P7; Q6IMN5; Q7Z371; Q8TE70; Q8TE71;
AC   Q96RN6; Q9H667; Q9HAL4;
DE   RecName: Full=Caprin-2;
DE   AltName: Full=C1q domain-containing protein 1;
DE   AltName: Full=Cytoplasmic activation/proliferation-associated protein 2;
DE   AltName: Full=Gastric cancer multidrug resistance-associated protein;
DE   AltName: Full=Protein EEG-1;
DE   AltName: Full=RNA granule protein 140;
GN   Name=CAPRIN2; Synonyms=C1QDC1, EEG1, KIAA1873, RNG140;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   CAPS1_HUMAN             Reviewed;        1353 AA.
AC   Q9ULU8; A6NF60; Q13339; Q6GQQ6; Q8N2Z5; Q8N3M7; Q8NFR0; Q96BC2;
DE   RecName: Full=Calcium-dependent secretion activator 1;
DE   AltName: Full=Calcium-dependent activator protein for secretion 1;
DE            Short=CAPS-1;
GN   Name=CADPS; Synonyms=CAPS, CAPS1, KIAA1121;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050432; P:catecholamine secretion; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016082; P:synaptic vesicle priming; IEA:Ensembl.
DR   GO; GO:0016050; P:vesicle organization; IEA:Ensembl.
//
ID   CAPS2_HUMAN             Reviewed;        1296 AA.
AC   Q86UW7; A4D0X3; B7ZM56; Q658Q2; Q7Z5T7; Q8IZW9; Q8N7M4; Q9H6P4;
AC   Q9HCI1; Q9NWK8;
DE   RecName: Full=Calcium-dependent secretion activator 2;
DE   AltName: Full=Calcium-dependent activator protein for secretion 2;
DE            Short=CAPS-2;
GN   Name=CADPS2; Synonyms=CAPS2, KIAA1591;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016082; P:synaptic vesicle priming; IEA:Ensembl.
//
ID   CAPSL_HUMAN             Reviewed;         208 AA.
AC   Q8WWF8;
DE   RecName: Full=Calcyphosin-like protein;
GN   Name=CAPSL;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CAPZB_HUMAN             Reviewed;         277 AA.
AC   P47756; Q32Q68; Q5U0L4; Q8TB49; Q9NUC4;
DE   RecName: Full=F-actin-capping protein subunit beta;
DE   AltName: Full=CapZ beta;
GN   Name=CAPZB;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:Ensembl.
//
ID   CAR10_HUMAN             Reviewed;        1032 AA.
AC   Q9BWT7; Q14CQ8; Q5TFG6; Q9UGR5; Q9UGR6; Q9Y3H0;
DE   RecName: Full=Caspase recruitment domain-containing protein 10;
DE   AltName: Full=CARD-containing MAGUK protein 3;
DE            Short=Carma 3;
GN   Name=CARD10; Synonyms=CARMA3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CAR11_HUMAN             Reviewed;        1154 AA.
AC   Q9BXL7; A4D1Z7; Q2NKN7; Q548H3;
DE   RecName: Full=Caspase recruitment domain-containing protein 11;
DE   AltName: Full=CARD-containing MAGUK protein 1;
DE            Short=Carma 1;
GN   Name=CARD11; Synonyms=CARMA1;
DR   GO; GO:0050700; F:CARD domain binding; IPI:UniProtKB.
DR   GO; GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0046939; P:nucleotide phosphorylation; NAS:GOC.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045577; P:regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045580; P:regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045061; P:thymic T cell selection; IEA:Ensembl.
//
ID   CAR14_HUMAN             Reviewed;        1004 AA.
AC   Q9BXL6; B8QQJ3; Q9BVB5;
DE   RecName: Full=Caspase recruitment domain-containing protein 14;
DE   AltName: Full=CARD-containing MAGUK protein 2;
DE            Short=Carma 2;
GN   Name=CARD14; Synonyms=CARMA2;
DR   GO; GO:0050700; F:CARD domain binding; IPI:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
//
ID   CAR17_HUMAN             Reviewed;         110 AA.
AC   Q5XLA6;
DE   RecName: Full=Caspase recruitment domain-containing protein 17;
DE   AltName: Full=Caspase-1 inhibitor INCA;
DE   AltName: Full=Inhibitory caspase recruitment domain protein;
GN   Name=CARD17; Synonyms=INCA;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CAR16_HUMAN             Reviewed;         197 AA.
AC   Q5EG05; Q96RJ9;
DE   RecName: Full=Caspase recruitment domain-containing protein 16;
DE   AltName: Full=CARD only domain-containing protein 1;
DE   AltName: Full=Caspase-1 inhibitor COP;
DE   AltName: Full=Pseudo interleukin-1 beta converting enzyme;
DE            Short=Pseudo-ICE;
GN   Name=CARD16; Synonyms=COP, COP1;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CAR18_HUMAN             Reviewed;          90 AA.
AC   P57730; A2RRF8;
DE   RecName: Full=Caspase recruitment domain-containing protein 18;
DE   AltName: Full=Caspase-1 inhibitor Iceberg;
GN   Name=CARD18; Synonyms=ICEBERG; ORFNames=UNQ5804/PRO19611;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CARD6_HUMAN             Reviewed;        1037 AA.
AC   Q9BX69; Q52LR2;
DE   RecName: Full=Caspase recruitment domain-containing protein 6;
GN   Name=CARD6;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CARD8_HUMAN             Reviewed;         431 AA.
AC   Q9Y2G2; B5KVR6; B7Z496; B7Z4A2; E9PEM7; G3XAM9; Q6PGP8; Q96P82;
DE   RecName: Full=Caspase recruitment domain-containing protein 8;
DE   AltName: Full=Apoptotic protein NDPP1;
DE   AltName: Full=CARD-inhibitor of NF-kappa-B-activating ligand;
DE            Short=CARDINAL;
DE   AltName: Full=DACAR;
DE   AltName: Full=Tumor up-regulated CARD-containing antagonist of CASP9;
DE            Short=TUCAN;
GN   Name=CARD8; Synonyms=KIAA0955, NDPP1;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0032089; F:NACHT domain binding; IPI:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:GOC.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:HGNC.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.
//
ID   CARD9_HUMAN             Reviewed;         536 AA.
AC   Q9H257; Q5SXM5; Q5SXM6; Q9H854;
DE   RecName: Full=Caspase recruitment domain-containing protein 9;
DE            Short=hCARD9;
GN   Name=CARD9;
DR   GO; GO:0050700; F:CARD domain binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:MGI.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IDA:MGI.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045076; P:regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045408; P:regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042534; P:regulation of tumor necrosis factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0009620; P:response to fungus; IEA:Ensembl.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0032494; P:response to peptidoglycan; IEA:Ensembl.
//
ID   CARF_HUMAN              Reviewed;         580 AA.
AC   Q9NXV6; Q8TBM5; Q9NYH0;
DE   RecName: Full=CDKN2A-interacting protein;
DE   AltName: Full=Collaborator of ARF;
GN   Name=CDKN2AIP; Synonyms=CARF;
DR   GO; GO:0002039; F:p53 binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IMP:BHF-UCL.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:BHF-UCL.
//
ID   CARM1_HUMAN             Reviewed;         608 AA.
AC   Q86X55; A6NN38;
DE   RecName: Full=Histone-arginine methyltransferase CARM1;
DE            EC=2.1.1.-;
DE            EC=2.1.1.125;
DE   AltName: Full=Coactivator-associated arginine methyltransferase 1;
DE   AltName: Full=Protein arginine N-methyltransferase 4;
GN   Name=CARM1; Synonyms=PRMT4;
DR   GO; GO:0008013; F:beta-catenin binding; TAS:AgBase.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; ISS:UniProtKB.
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035642; F:histone methyltransferase activity (H3-R17 specific); ISS:UniProtKB.
DR   GO; GO:0008469; F:histone-arginine N-methyltransferase activity; IBA:RefGenome.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008276; F:protein methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0035242; F:protein-arginine omega-N asymmetric methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0060350; P:endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0034971; P:histone H3-R17 methylation; ISS:UniProtKB.
DR   GO; GO:0034970; P:histone H3-R2 methylation; IMP:UniProtKB.
DR   GO; GO:0016571; P:histone methylation; IDA:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0009405; P:pathogenesis; IEA:InterPro.
DR   GO; GO:0019919; P:peptidyl-arginine methylation, to asymmetrical-dimethyl arginine; IBA:RefGenome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0003420; P:regulation of growth plate cartilage chondrocyte proliferation; IEA:Ensembl.
DR   GO; GO:0033146; P:regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CARTF_HUMAN             Reviewed;         725 AA.
AC   Q8N187; Q8ND29; Q8WXC0; Q96J78; Q96Q38; Q96Q39; Q9H712;
DE   RecName: Full=Calcium-responsive transcription factor;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein;
DE   AltName: Full=Calcium-response factor;
DE            Short=CaRF;
DE   AltName: Full=Testis development protein NYD-SP24;
GN   Name=CARF; Synonyms=ALS2CR8;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0035865; P:cellular response to potassium ion; IDA:UniProtKB.
DR   GO; GO:0061400; P:positive regulation of transcription from RNA polymerase II promoter in response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CART_HUMAN              Reviewed;         116 AA.
AC   Q16568; Q6FG92;
DE   RecName: Full=Cocaine- and amphetamine-regulated transcript protein;
DE   Contains:
DE     RecName: Full=CART(1-39);
DE   Contains:
DE     RecName: Full=CART(42-89);
DE   Flags: Precursor;
GN   Name=CARTPT; Synonyms=CART;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000186; P:activation of MAPKK activity; ISS:HGNC.
DR   GO; GO:0008343; P:adult feeding behavior; ISS:HGNC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IDA:HGNC.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:HGNC.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:HGNC.
DR   GO; GO:0032099; P:negative regulation of appetite; ISS:HGNC.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IMP:HGNC.
DR   GO; GO:0070093; P:negative regulation of glucagon secretion; IEA:Ensembl.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; TAS:HGNC.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IDA:HGNC.
DR   GO; GO:0032812; P:positive regulation of epinephrine secretion; IDA:HGNC.
DR   GO; GO:0051971; P:positive regulation of transmission of nerve impulse; IDA:HGNC.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0070253; P:somatostatin secretion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:UniProtKB-KW.
//
ID   CASA1_HUMAN             Reviewed;         185 AA.
AC   P47710; A1A510; A1A511; E9PB60; Q4PNR5;
DE   RecName: Full=Alpha-S1-casein;
DE   Contains:
DE     RecName: Full=Casoxin-D;
DE   Flags: Precursor;
GN   Name=CSN1S1; Synonyms=CASA, CSN1;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   CASB_HUMAN              Reviewed;         226 AA.
AC   P05814; Q4VAZ9; Q9UCM5;
DE   RecName: Full=Beta-casein;
DE   Flags: Precursor;
GN   Name=CSN2; Synonyms=CASB;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
//
ID   CASC1_HUMAN             Reviewed;         716 AA.
AC   Q6TDU7; B4DNP2; F5H6T6; Q17RL2; Q4G171; Q5U5K5; Q9NV50;
DE   RecName: Full=Protein CASC1;
DE   AltName: Full=Cancer susceptibility candidate gene 1 protein;
DE   AltName: Full=Lung adenoma susceptibility 1-like protein;
GN   Name=CASC1; Synonyms=LAS1;
//
ID   CASC2_HUMAN             Reviewed;          76 AA.
AC   Q8IU53; Q2M1K1; Q8IUI3;
DE   RecName: Full=Protein CASC2, isoforms 1/2;
DE   AltName: Full=Cancer susceptibility candidate gene 2 protein isoforms 1/2;
GN   Name=CASC2; Synonyms=C10orf5;
//
ID   CASC3_HUMAN             Reviewed;         703 AA.
AC   O15234; A8K8R0;
DE   RecName: Full=Protein CASC3;
DE   AltName: Full=Cancer susceptibility candidate gene 3 protein;
DE   AltName: Full=Metastatic lymph node gene 51 protein;
DE            Short=MLN 51;
DE   AltName: Full=Protein barentsz;
DE            Short=Btz;
GN   Name=CASC3; Synonyms=MLN51;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008298; P:intracellular mRNA localization; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   CASC4_HUMAN             Reviewed;         433 AA.
AC   Q6P4E1; G5E934; Q6UY45; Q96EM1;
DE   RecName: Full=Protein CASC4;
DE   AltName: Full=Cancer susceptibility candidate gene 4 protein;
GN   Name=CASC4; ORFNames=UNQ2573/PRO6308;
//
ID   CASC5_HUMAN             Reviewed;        2342 AA.
AC   Q8NG31; Q8NHE1; Q8WXA6; Q9HCK2; Q9NR92;
DE   RecName: Full=Protein CASC5;
DE   AltName: Full=ALL1-fused gene from chromosome 15q14 protein;
DE            Short=AF15q14;
DE   AltName: Full=Bub-linking kinetochore protein;
DE            Short=Blinkin;
DE   AltName: Full=Cancer susceptibility candidate gene 5 protein;
DE   AltName: Full=Cancer/testis antigen 29;
DE            Short=CT29;
DE   AltName: Full=Kinetochore-null protein 1;
DE   AltName: Full=Protein D40/AF15q14;
GN   Name=CASC5; Synonyms=KIAA1570, KNL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001675; P:acrosome assembly; NAS:UniProtKB.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IDA:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0034501; P:protein localization to kinetochore; IDA:MGI.
DR   GO; GO:0071173; P:spindle assembly checkpoint; IDA:UniProtKB.
//
ID   CASD1_HUMAN             Reviewed;         797 AA.
AC   Q96PB1; B3KW13; O14574; Q3LIE2; Q6P4R4; Q9H6T9; Q9H770;
DE   RecName: Full=CAS1 domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=CASD1; Synonyms=C7orf12; ORFNames=Nbla04196;
//
ID   CASK_HUMAN              Reviewed;         182 AA.
AC   P07498; Q13575;
DE   RecName: Full=Kappa-casein;
DE   Flags: Precursor;
GN   Name=CSN3; Synonyms=CASK, CSN10, CSNK;
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
//
ID   CASL_HUMAN              Reviewed;         834 AA.
AC   Q14511; A8K9G7; A8MSJ9; G5E9Y9; Q5T9R4; Q5XKI0;
DE   RecName: Full=Enhancer of filamentation 1;
DE            Short=hEF1;
DE   AltName: Full=CRK-associated substrate-related protein;
DE            Short=CAS-L;
DE            Short=CasL;
DE   AltName: Full=Cas scaffolding protein family member 2;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 9;
DE            Short=NEDD-9;
DE   AltName: Full=Renal carcinoma antigen NY-REN-12;
DE   AltName: Full=p105;
DE   Contains:
DE     RecName: Full=Enhancer of filamentation 1 p55;
GN   Name=NEDD9; Synonyms=CASL, CASS2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CASP1_HUMAN             Reviewed;         404 AA.
AC   P29466; B5MDZ1; Q53EY6; Q6DMQ1; Q6GSS3; Q6PI75; Q9UCN3;
DE   RecName: Full=Caspase-1;
DE            Short=CASP-1;
DE            EC=3.4.22.36;
DE   AltName: Full=Interleukin-1 beta convertase;
DE            Short=IL-1BC;
DE   AltName: Full=Interleukin-1 beta-converting enzyme;
DE            Short=ICE;
DE            Short=IL-1 beta-converting enzyme;
DE   AltName: Full=p45;
DE   Contains:
DE     RecName: Full=Caspase-1 subunit p20;
DE   Contains:
DE     RecName: Full=Caspase-1 subunit p10;
DE   Flags: Precursor;
GN   Name=CASP1; Synonyms=IL1BC, IL1BCE;
DR   GuidetoPHARMACOLOGY; 1617; -.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; TAS:ProtInc.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:GOC.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0071310; P:cellular response to organic substance; IDA:MGI.
DR   GO; GO:0097194; P:execution phase of apoptosis; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032611; P:interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0051882; P:mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0050717; P:positive regulation of interleukin-1 alpha secretion; IEA:Ensembl.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0070269; P:pyroptosis; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IBA:RefGenome.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CASP2_HUMAN             Reviewed;         452 AA.
AC   P42575; A8K5F9; D3DXD6; E9PDN0; P42576; Q59F21; Q7KZL6; Q86UJ3;
AC   Q9BUP7; Q9BZK9; Q9BZL0;
DE   RecName: Full=Caspase-2;
DE            Short=CASP-2;
DE            EC=3.4.22.55;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 2;
DE            Short=NEDD-2;
DE   AltName: Full=Protease ICH-1;
DE   Contains:
DE     RecName: Full=Caspase-2 subunit p18;
DE   Contains:
DE     RecName: Full=Caspase-2 subunit p13;
DE   Contains:
DE     RecName: Full=Caspase-2 subunit p12;
DE   Flags: Precursor;
GN   Name=CASP2; Synonyms=ICH1, NEDD2;
DR   GuidetoPHARMACOLOGY; 1618; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0097194; P:execution phase of apoptosis; TAS:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; TAS:UniProtKB.
DR   GO; GO:0001554; P:luteolysis; IEA:Ensembl.
DR   GO; GO:0003407; P:neural retina development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0016485; P:protein processing; IDA:BHF-UCL.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
//
ID   CASP3_HUMAN             Reviewed;         277 AA.
AC   P42574; A8K5M2; D3DP53; Q96AN1; Q96KP2;
DE   RecName: Full=Caspase-3;
DE            Short=CASP-3;
DE            EC=3.4.22.56;
DE   AltName: Full=Apopain;
DE   AltName: Full=Cysteine protease CPP32;
DE            Short=CPP-32;
DE   AltName: Full=Protein Yama;
DE   AltName: Full=SREBP cleavage activity 1;
DE            Short=SCA-1;
DE   Contains:
DE     RecName: Full=Caspase-3 subunit p17;
DE   Contains:
DE     RecName: Full=Caspase-3 subunit p12;
DE   Flags: Precursor;
GN   Name=CASP3; Synonyms=CPP32;
DR   GuidetoPHARMACOLOGY; 1619; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; EXP:Reactome.
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097200; F:cysteine-type endopeptidase activity involved in execution phase of apoptosis; IMP:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; TAS:Reactome.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0034349; P:glial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IBA:RefGenome.
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IGI:MGI.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030220; P:platelet formation; TAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; TAS:BHF-UCL.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
//
ID   CASP4_HUMAN             Reviewed;         377 AA.
AC   P49662; A2NHL8; A2NHM0;
DE   RecName: Full=Caspase-4;
DE            Short=CASP-4;
DE            EC=3.4.22.57;
DE   AltName: Full=ICE(rel)-II;
DE   AltName: Full=Protease ICH-2;
DE   AltName: Full=Protease TX;
DE   Contains:
DE     RecName: Full=Caspase-4 subunit 1;
DE   Contains:
DE     RecName: Full=Caspase-4 subunit 2;
DE   Flags: Precursor;
GN   Name=CASP4; Synonyms=ICH2;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0097194; P:execution phase of apoptosis; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0050727; P:regulation of inflammatory response; IBA:RefGenome.
//
ID   CASP5_HUMAN             Reviewed;         434 AA.
AC   P51878; B4DKP5; Q0QVY7; Q0QVY8; Q0QVZ0; Q0QVZ1; Q0QVZ2; Q14DD6;
AC   Q1HBJ3; Q6DJV7;
DE   RecName: Full=Caspase-5;
DE            Short=CASP-5;
DE            EC=3.4.22.58;
DE   AltName: Full=ICE(rel)-III;
DE   AltName: Full=Protease ICH-3;
DE   AltName: Full=Protease TY;
DE   Contains:
DE     RecName: Full=Caspase-5 subunit p20;
DE   Contains:
DE     RecName: Full=Caspase-5 subunit p10;
DE   Flags: Precursor;
GN   Name=CASP5; Synonyms=ICH3;
DR   GuidetoPHARMACOLOGY; 1621; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0097194; P:execution phase of apoptosis; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0050727; P:regulation of inflammatory response; IBA:RefGenome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   CASP6_HUMAN             Reviewed;         293 AA.
AC   P55212; Q9BQE7;
DE   RecName: Full=Caspase-6;
DE            Short=CASP-6;
DE            EC=3.4.22.59;
DE   AltName: Full=Apoptotic protease Mch-2;
DE   Contains:
DE     RecName: Full=Caspase-6 subunit p18;
DE   Contains:
DE     RecName: Full=Caspase-6 subunit p11;
DE   Flags: Precursor;
GN   Name=CASP6; Synonyms=MCH2;
DR   GuidetoPHARMACOLOGY; 1622; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   CASP7_HUMAN             Reviewed;         303 AA.
AC   P55210; B4DQU7; B5BU45; D3DRB8; Q13364; Q53YD5; Q5SVL0; Q5SVL3;
AC   Q96BA0;
DE   RecName: Full=Caspase-7;
DE            Short=CASP-7;
DE            EC=3.4.22.60;
DE   AltName: Full=Apoptotic protease Mch-3;
DE   AltName: Full=CMH-1;
DE   AltName: Full=ICE-like apoptotic protease 3;
DE            Short=ICE-LAP3;
DE   Contains:
DE     RecName: Full=Caspase-7 subunit p20;
DE   Contains:
DE     RecName: Full=Caspase-7 subunit p11;
DE   Flags: Precursor;
GN   Name=CASP7; Synonyms=MCH3;
DR   GuidetoPHARMACOLOGY; 1623; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0097194; P:execution phase of apoptosis; IBA:RefGenome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
//
ID   CASP8_HUMAN             Reviewed;         479 AA.
AC   Q14790; O14676; Q14791; Q14792; Q14793; Q14794; Q14795; Q14796;
AC   Q15780; Q15806; Q53TT5; Q8TDI1; Q8TDI2; Q8TDI3; Q8TDI4; Q8TDI5;
AC   Q96T22; Q9C0K4; Q9UQ81;
DE   RecName: Full=Caspase-8;
DE            Short=CASP-8;
DE            EC=3.4.22.61;
DE   AltName: Full=Apoptotic cysteine protease;
DE   AltName: Full=Apoptotic protease Mch-5;
DE   AltName: Full=CAP4;
DE   AltName: Full=FADD-homologous ICE/ced-3-like protease;
DE   AltName: Full=FADD-like ICE;
DE            Short=FLICE;
DE   AltName: Full=ICE-like apoptotic protease 5;
DE   AltName: Full=MORT1-associated ced-3 homolog;
DE            Short=MACH;
DE   Contains:
DE     RecName: Full=Caspase-8 subunit p18;
DE   Contains:
DE     RecName: Full=Caspase-8 subunit p10;
DE   Flags: Precursor;
GN   Name=CASP8; Synonyms=MCH5;
DR   GuidetoPHARMACOLOGY; 1624; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097199; F:cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0035877; F:death effector domain binding; IPI:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IMP:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IBA:RefGenome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0030225; P:macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030101; P:natural killer cell activation; TAS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0070243; P:regulation of thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0032025; P:response to cobalt ion; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0060715; P:syncytiotrophoblast cell differentiation involved in labyrinthine layer development; TAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CASP9_HUMAN             Reviewed;         416 AA.
AC   P55211; B4E1A3; O95348; Q53Y70; Q5JRU9; Q5UGI1; Q92852; Q9BQ62;
AC   Q9UEQ3; Q9UIJ8;
DE   RecName: Full=Caspase-9;
DE            Short=CASP-9;
DE            EC=3.4.22.62;
DE   AltName: Full=Apoptotic protease Mch-6;
DE   AltName: Full=Apoptotic protease-activating factor 3;
DE            Short=APAF-3;
DE   AltName: Full=ICE-like apoptotic protease 6;
DE            Short=ICE-LAP6;
DE   Contains:
DE     RecName: Full=Caspase-9 subunit p35;
DE   Contains:
DE     RecName: Full=Caspase-9 subunit p10;
DE   Flags: Precursor;
GN   Name=CASP9; Synonyms=MCH6;
DR   GuidetoPHARMACOLOGY; 1625; -.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IDA:UniProtKB.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034349; P:glial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030220; P:platelet formation; TAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:2001020; P:regulation of response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0032025; P:response to cobalt ion; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IDA:UniProtKB.
//
ID   CASPA_HUMAN             Reviewed;         521 AA.
AC   Q92851; Q68HC0; Q6KF62; Q6KF63; Q8IUP5; Q8WYQ8; Q99845; Q9Y2U6;
AC   Q9Y2U7;
DE   RecName: Full=Caspase-10;
DE            Short=CASP-10;
DE            EC=3.4.22.63;
DE   AltName: Full=Apoptotic protease Mch-4;
DE   AltName: Full=FAS-associated death domain protein interleukin-1B-converting enzyme 2;
DE            Short=FLICE2;
DE   AltName: Full=ICE-like apoptotic protease 4;
DE   Contains:
DE     RecName: Full=Caspase-10 subunit p23/17;
DE   Contains:
DE     RecName: Full=Caspase-10 subunit p12;
DE   Flags: Precursor;
GN   Name=CASP10; Synonyms=MCH4;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0097199; F:cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0035877; F:death effector domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CASPC_HUMAN             Reviewed;         341 AA.
AC   Q6UXS9; D6RBN7;
DE   RecName: Full=Inactive caspase-12;
DE            Short=CASP-12;
GN   Name=CASP12; ORFNames=UNQ9415/PRO34398;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IBA:RefGenome.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
//
ID   CASPE_HUMAN             Reviewed;         242 AA.
AC   P31944; O95823; Q3SYC9;
DE   RecName: Full=Caspase-14;
DE            Short=CASP-14;
DE            EC=3.4.22.-;
DE   Contains:
DE     RecName: Full=Caspase-14 subunit p19;
DE   Contains:
DE     RecName: Full=Caspase-14 subunit p10;
DE   Flags: Precursor;
GN   Name=CASP14;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0070268; P:cornification; TAS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0031424; P:keratinization; TAS:UniProtKB.
//
ID   CASPG_HUMAN             Reviewed;         183 AA.
AC   P0CB46;
DE   RecName: Full=Putative caspase-16;
DE            EC=3.4.22.-;
GN   Name=CASP16; Synonyms=CASP14L;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
//
ID   CASP_HUMAN              Reviewed;         678 AA.
AC   Q13948; B3KWH3; B3KWH8; B4DZZ2; G3V1Z6; J3KPQ6; Q53GU9; Q8TBS3;
DE   RecName: Full=Protein CASP;
GN   Name=CUX1; Synonyms=CUTL1;
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
//
ID   CASQ1_HUMAN             Reviewed;         396 AA.
AC   P31415; B1AKZ2; B2R863; Q8TBW7;
DE   RecName: Full=Calsequestrin-1;
DE   AltName: Full=Calmitin;
DE   AltName: Full=Calsequestrin, skeletal muscle isoform;
DE   Flags: Precursor;
GN   Name=CASQ1; Synonyms=CASQ;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051282; P:regulation of sequestering of calcium ion; IEA:Ensembl.
DR   GO; GO:0014809; P:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; IEA:Ensembl.
DR   GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CASQ2_HUMAN             Reviewed;         399 AA.
AC   O14958; B2R7M6; Q5T1D2; Q8TBW8;
DE   RecName: Full=Calsequestrin-2;
DE   AltName: Full=Calsequestrin, cardiac muscle isoform;
DE   Flags: Precursor;
GN   Name=CASQ2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0071313; P:cellular response to caffeine; IMP:BHF-UCL.
DR   GO; GO:0005513; P:detection of calcium ion; TAS:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:1901017; P:negative regulation of potassium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; ISS:BHF-UCL.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0051258; P:protein polymerization; IDA:BHF-UCL.
DR   GO; GO:0086029; P:Purkinje myocyte to ventricular cardiac muscle cell signaling; NAS:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IMP:BHF-UCL.
DR   GO; GO:0010649; P:regulation of cell communication by electrical coupling; IMP:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; ISS:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:BHF-UCL.
DR   GO; GO:0051208; P:sequestering of calcium ion; IDA:BHF-UCL.
DR   GO; GO:0006941; P:striated muscle contraction; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CASR_HUMAN              Reviewed;        1078 AA.
AC   P41180; Q13912; Q16108; Q16109; Q16110; Q16379; Q2M1T0; Q4PJ19;
DE   RecName: Full=Extracellular calcium-sensing receptor;
DE            Short=CaSR;
DE   AltName: Full=Parathyroid cell calcium-sensing receptor 1;
DE            Short=PCaR1;
DE   Flags: Precursor;
GN   Name=CASR; Synonyms=GPRC2A, PCAR1;
DR   GuidetoPHARMACOLOGY; 54; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0070509; P:calcium ion import; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0007635; P:chemosensory behavior; TAS:ProtInc.
DR   GO; GO:0005513; P:detection of calcium ion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
//
ID   CASS4_HUMAN             Reviewed;         786 AA.
AC   Q9NQ75; E1P5Z8; Q5QPD6; Q96K09; Q9BYL5;
DE   RecName: Full=Cas scaffolding protein family member 4;
DE   AltName: Full=HEF-like protein;
DE   AltName: Full=HEF1-EFS-p130Cas-like protein;
DE            Short=HEPL;
GN   Name=CASS4; Synonyms=C20orf32, HEFL;
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CASZ1_HUMAN             Reviewed;        1759 AA.
AC   Q86V15; Q078S9; Q2EN02; Q5T9S1; Q6ZNM8; Q8WX49; Q8WX50; Q9BT16;
AC   Q9NXC6;
DE   RecName: Full=Zinc finger protein castor homolog 1;
DE   AltName: Full=Castor-related protein;
DE   AltName: Full=Putative survival-related protein;
DE   AltName: Full=Zinc finger protein 693;
GN   Name=CASZ1; Synonyms=CST, SRG, ZNF693;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CATA_HUMAN              Reviewed;         527 AA.
AC   P04040; A8K6C0; B2RCZ9; D3DR07; Q2M1U4; Q4VXX5; Q9BWT9; Q9UC85;
DE   RecName: Full=Catalase;
DE            EC=1.11.1.6;
GN   Name=CAT;
DR   GO; GO:0004046; F:aminoacylase activity; IEA:Ensembl.
DR   GO; GO:0016209; F:antioxidant activity; IDA:UniProtKB.
DR   GO; GO:0004096; F:catalase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050661; F:NADP binding; IDA:UniProtKB.
DR   GO; GO:0016684; F:oxidoreductase activity, acting on peroxide as acceptor; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0009060; P:aerobic respiration; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0020027; P:hemoglobin metabolic process; IEA:Ensembl.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0042697; P:menopause; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0000302; P:response to reactive oxygen species; IMP:UniProtKB.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0009650; P:UV protection; IMP:UniProtKB.
//
ID   CATB_HUMAN              Reviewed;         339 AA.
AC   P07858; B3KQR5; B3KRR5; Q503A6; Q96D87;
DE   RecName: Full=Cathepsin B;
DE            EC=3.4.22.1;
DE   AltName: Full=APP secretase;
DE            Short=APPS;
DE   AltName: Full=Cathepsin B1;
DE   Contains:
DE     RecName: Full=Cathepsin B light chain;
DE   Contains:
DE     RecName: Full=Cathepsin B heavy chain;
DE   Flags: Precursor;
GN   Name=CTSB; Synonyms=CPSB;
DR   GuidetoPHARMACOLOGY; 2343; -.
DR   GO; GO:0005518; F:collagen binding; IDA:BHF-UCL.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:BHF-UCL.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:BHF-UCL.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IEA:InterPro.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   CATC_HUMAN              Reviewed;         463 AA.
AC   P53634; A8K7V2; B5MDD5; Q2HIY8; Q53G93; Q71E75; Q71E76; Q7M4N9;
AC   Q7Z3G7; Q7Z5U7; Q8WY99; Q8WYA7; Q8WYA8;
DE   RecName: Full=Dipeptidyl peptidase 1;
DE            EC=3.4.14.1;
DE   AltName: Full=Cathepsin C;
DE   AltName: Full=Cathepsin J;
DE   AltName: Full=Dipeptidyl peptidase I;
DE            Short=DPP-I;
DE            Short=DPPI;
DE   AltName: Full=Dipeptidyl transferase;
DE   Contains:
DE     RecName: Full=Dipeptidyl peptidase 1 exclusion domain chain;
DE     AltName: Full=Dipeptidyl peptidase I exclusion domain chain;
DE   Contains:
DE     RecName: Full=Dipeptidyl peptidase 1 heavy chain;
DE     AltName: Full=Dipeptidyl peptidase I heavy chain;
DE   Contains:
DE     RecName: Full=Dipeptidyl peptidase 1 light chain;
DE     AltName: Full=Dipeptidyl peptidase I light chain;
DE   Flags: Precursor;
GN   Name=CTSC; Synonyms=CPPI;
DR   GO; GO:0031404; F:chloride ion binding; IEA:Ensembl.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0016505; F:peptidase activator activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0001913; P:T cell mediated cytotoxicity; IEA:Ensembl.
//
ID   CATD_HUMAN              Reviewed;         412 AA.
AC   P07339; Q6IB57;
DE   RecName: Full=Cathepsin D;
DE            EC=3.4.23.5;
DE   Contains:
DE     RecName: Full=Cathepsin D light chain;
DE   Contains:
DE     RecName: Full=Cathepsin D heavy chain;
DE   Flags: Precursor;
GN   Name=CTSD; Synonyms=CPSD;
DR   GuidetoPHARMACOLOGY; 2345; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   CATE_HUMAN              Reviewed;         401 AA.
AC   P14091; Q5TZ01; Q5TZ02; Q9NY58; Q9UCE3; Q9UCE4;
DE   RecName: Full=Cathepsin E;
DE            EC=3.4.23.34;
DE   Contains:
DE     RecName: Full=Cathepsin E form I;
DE   Contains:
DE     RecName: Full=Cathepsin E form II;
DE   Flags: Precursor;
GN   Name=CTSE;
DR   GuidetoPHARMACOLOGY; 2346; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IDA:UniProtKB.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0016540; P:protein autoprocessing; IEA:Ensembl.
//
ID   CATF_HUMAN              Reviewed;         484 AA.
AC   Q9UBX1; B2R964; O95240; Q9NSU4; Q9UKQ5;
DE   RecName: Full=Cathepsin F;
DE            Short=CATSF;
DE            EC=3.4.22.41;
DE   Flags: Precursor;
GN   Name=CTSF;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CATG_HUMAN              Reviewed;         255 AA.
AC   P08311; Q6IBJ6; Q9UCA5; Q9UCU6;
DE   RecName: Full=Cathepsin G;
DE            Short=CG;
DE            EC=3.4.21.20;
DE   Flags: Precursor;
GN   Name=CTSG;
DR   GuidetoPHARMACOLOGY; 2348; -.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050832; P:defense response to fungus; IBA:RefGenome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IBA:RefGenome.
DR   GO; GO:0050778; P:positive regulation of immune response; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   CATH_HUMAN              Reviewed;         335 AA.
AC   P09668; B2RBK0; Q96NY6; Q9BUM7;
DE   RecName: Full=Pro-cathepsin H;
DE   Contains:
DE     RecName: Full=Cathepsin H mini chain;
DE   Contains:
DE     RecName: Full=Cathepsin H;
DE              EC=3.4.22.16;
DE   Contains:
DE     RecName: Full=Cathepsin H heavy chain;
DE   Contains:
DE     RecName: Full=Cathepsin H light chain;
DE   Flags: Precursor;
GN   Name=CTSH; Synonyms=CPSB;
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0030108; F:HLA-A specific activating MHC class I receptor activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0070324; F:thyroid hormone binding; IDA:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; IEP:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; TAS:UniProtKB.
DR   GO; GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0060448; P:dichotomous subdivision of terminal units involved in lung branching; ISS:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0002764; P:immune response-regulating signaling pathway; IDA:UniProtKB.
DR   GO; GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0010813; P:neuropeptide catabolic process; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0010952; P:positive regulation of peptidase activity; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0043129; P:surfactant homeostasis; IDA:UniProtKB.
DR   GO; GO:0001913; P:T cell mediated cytotoxicity; ISS:UniProtKB.
DR   GO; GO:0031638; P:zymogen activation; IDA:UniProtKB.
//
ID   CATIN_HUMAN             Reviewed;         758 AA.
AC   Q8WUQ7; A6NNA9; A9UL12; O75229; Q7LE08; Q9BTA6; Q9Y5A4;
DE   RecName: Full=Cactin;
DE   AltName: Full=Renal carcinoma antigen NY-REN-24;
GN   Name=CACTIN; Synonyms=C19orf29;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0032688; P:negative regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032717; P:negative regulation of interleukin-8 production; IDA:UniProtKB.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0060339; P:negative regulation of type I interferon-mediated signaling pathway; IMP:UniProtKB.
//
ID   CATIP_HUMAN             Reviewed;         387 AA.
AC   Q7Z7H3;
DE   RecName: Full=Ciliogenesis-associated TTC17-interacting protein;
GN   Name=CATIP; Synonyms=C2orf62;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0044782; P:cilium organization; IMP:UniProtKB.
//
ID   CATK_HUMAN              Reviewed;         329 AA.
AC   P43235; Q6FHS6;
DE   RecName: Full=Cathepsin K;
DE            EC=3.4.22.38;
DE   AltName: Full=Cathepsin O;
DE   AltName: Full=Cathepsin O2;
DE   AltName: Full=Cathepsin X;
DE   Flags: Precursor;
GN   Name=CTSK; Synonyms=CTSO, CTSO2;
DR   GuidetoPHARMACOLOGY; 2350; -.
DR   GO; GO:0005518; F:collagen binding; IDA:BHF-UCL.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0001968; F:fibronectin binding; IPI:BHF-UCL.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:BHF-UCL.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001957; P:intramembranous ossification; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   CATL1_HUMAN             Reviewed;         333 AA.
AC   P07711; Q6IAV1; Q96QJ0;
DE   RecName: Full=Cathepsin L1;
DE            EC=3.4.22.15;
DE   AltName: Full=Cathepsin L;
DE   AltName: Full=Major excreted protein;
DE            Short=MEP;
DE   Contains:
DE     RecName: Full=Cathepsin L1 heavy chain;
DE   Contains:
DE     RecName: Full=Cathepsin L1 light chain;
DE   Flags: Precursor;
GN   Name=CTSL; Synonyms=CTSL1;
DR   GuidetoPHARMACOLOGY; 2351; -.
DR   GO; GO:0005518; F:collagen binding; IDA:BHF-UCL.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0001968; F:fibronectin binding; IPI:BHF-UCL.
DR   GO; GO:0042393; F:histone binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:BHF-UCL.
DR   GO; GO:0002250; P:adaptive immune response; IEP:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; TAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0071888; P:macrophage apoptotic process; NAS:BHF-UCL.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   CATL2_HUMAN             Reviewed;         334 AA.
AC   O60911; O60233; Q2TB86; Q5T1U0;
DE   RecName: Full=Cathepsin L2;
DE            EC=3.4.22.43;
DE   AltName: Full=Cathepsin U;
DE   AltName: Full=Cathepsin V;
DE   Flags: Precursor;
GN   Name=CTSV; Synonyms=CATL2, CTSL2, CTSU; ORFNames=UNQ268/PRO305;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:Ensembl.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0048102; P:autophagic cell death; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0034698; P:response to gonadotropin; IEA:Ensembl.
DR   GO; GO:0060008; P:Sertoli cell differentiation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CATL3_HUMAN             Reviewed;         218 AA.
AC   Q5NE16;
DE   RecName: Full=Putative inactive cathepsin L-like protein CTSL3P;
DE   AltName: Full=Cathepsin L3 pseudogene;
DE   AltName: Full=HCTSL-s;
GN   Name=CTSL3P; Synonyms=CTSL3;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
//
ID   CATO_HUMAN              Reviewed;         321 AA.
AC   P43234;
DE   RecName: Full=Cathepsin O;
DE            EC=3.4.22.42;
DE   Flags: Precursor;
GN   Name=CTSO; Synonyms=CTSO1;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CATR1_HUMAN             Reviewed;          79 AA.
AC   Q13166;
DE   RecName: Full=CATR tumorigenic conversion 1 protein;
DE   AltName: Full=CATR1.3;
GN   Name=CATR1;
//
ID   CATS_HUMAN              Reviewed;         331 AA.
AC   P25774; B4DWC9; D3DV05; Q5T5I0; Q6FHS5; Q9BUG3;
DE   RecName: Full=Cathepsin S;
DE            EC=3.4.22.27;
DE   Flags: Precursor;
GN   Name=CTSS;
DR   GuidetoPHARMACOLOGY; 2353; -.
DR   GO; GO:0005518; F:collagen binding; IDA:BHF-UCL.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0001968; F:fibronectin binding; IPI:BHF-UCL.
DR   GO; GO:0043236; F:laminin binding; IDA:BHF-UCL.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:BHF-UCL.
DR   GO; GO:0002250; P:adaptive immune response; IEP:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; TAS:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0034769; P:basement membrane disassembly; IDA:BHF-UCL.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   CATW_HUMAN              Reviewed;         376 AA.
AC   P56202; Q86VT4;
DE   RecName: Full=Cathepsin W;
DE            EC=3.4.22.-;
DE   AltName: Full=Lymphopain;
DE   Flags: Precursor;
GN   Name=CTSW;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   CATZ_HUMAN              Reviewed;         303 AA.
AC   Q9UBR2; B2RC40; O75331; Q9UQV5; Q9UQV6;
DE   RecName: Full=Cathepsin Z;
DE            EC=3.4.18.1;
DE   AltName: Full=Cathepsin P;
DE   AltName: Full=Cathepsin X;
DE   Flags: Precursor;
GN   Name=CTSZ;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CAV1_HUMAN              Reviewed;         178 AA.
AC   Q03135; Q9UGP1; Q9UNG1; Q9UQH6;
DE   RecName: Full=Caveolin-1;
GN   Name=CAV1; Synonyms=CAV;
DR   GO; GO:0015485; F:cholesterol binding; TAS:HGNC.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0050998; F:nitric-oxide synthase binding; IPI:BHF-UCL.
DR   GO; GO:0005113; F:patched binding; NAS:BHF-UCL.
DR   GO; GO:0016504; F:peptidase activator activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0032947; F:protein complex scaffold; TAS:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0055074; P:calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; ISS:BHF-UCL.
DR   GO; GO:0070836; P:caveola assembly; IMP:BHF-UCL.
DR   GO; GO:0072584; P:caveolin-mediated endocytosis; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0071455; P:cellular response to hyperoxia; IMP:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEP:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0030301; P:cholesterol transport; TAS:HGNC.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0000188; P:inactivation of MAPK activity; ISS:BHF-UCL.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0019915; P:lipid storage; ISS:BHF-UCL.
DR   GO; GO:0032507; P:maintenance of protein location in cell; ISS:BHF-UCL.
DR   GO; GO:0030879; P:mammary gland development; ISS:BHF-UCL.
DR   GO; GO:0060056; P:mammary gland involution; ISS:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; ISS:BHF-UCL.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; ISS:BHF-UCL.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0048550; P:negative regulation of pinocytosis; IMP:UniProt.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0042524; P:negative regulation of tyrosine phosphorylation of Stat5 protein; IEA:Ensembl.
DR   GO; GO:0033484; P:nitric oxide homeostasis; ISS:BHF-UCL.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; ISS:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0048554; P:positive regulation of metalloenzyme activity; ISS:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; ISS:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.
DR   GO; GO:0008104; P:protein localization; ISS:BHF-UCL.
DR   GO; GO:2000286; P:receptor internalization involved in canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0030193; P:regulation of blood coagulation; IMP:BHF-UCL.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0052547; P:regulation of peptidase activity; ISS:BHF-UCL.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0003057; P:regulation of the force of heart contraction by chemical signal; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; ISS:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IDA:MGI.
DR   GO; GO:0001666; P:response to hypoxia; ISS:BHF-UCL.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IDA:MGI.
DR   GO; GO:0007519; P:skeletal muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
DR   GO; GO:0006641; P:triglyceride metabolic process; ISS:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
DR   GO; GO:0042310; P:vasoconstriction; IEA:Ensembl.
DR   GO; GO:0016050; P:vesicle organization; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CAV2_HUMAN              Reviewed;         162 AA.
AC   P51636; A4D0U2; Q9UGM7;
DE   RecName: Full=Caveolin-2;
GN   Name=CAV2;
DR   GO; GO:0031748; F:D1 dopamine receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0070836; P:caveola assembly; IMP:BHF-UCL.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
DR   GO; GO:0007088; P:regulation of mitosis; IEP:BHF-UCL.
DR   GO; GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0048278; P:vesicle docking; IDA:BHF-UCL.
DR   GO; GO:0006906; P:vesicle fusion; IDA:BHF-UCL.
DR   GO; GO:0016050; P:vesicle organization; IDA:BHF-UCL.
//
ID   CAV3_HUMAN              Reviewed;         151 AA.
AC   P56539; A8K777; Q3T1A4;
DE   RecName: Full=Caveolin-3;
DE   AltName: Full=M-caveolin;
GN   Name=CAV3;
DR   GO; GO:0005246; F:calcium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0071253; F:connexin binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0019870; F:potassium channel inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IDA:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IPI:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0070836; P:caveola assembly; IDA:MGI.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0016049; P:cell growth; ISS:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; ISS:BHF-UCL.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:BHF-UCL.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0031579; P:membrane raft organization; ISS:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; ISS:BHF-UCL.
DR   GO; GO:0007517; P:muscle organ development; TAS:UniProtKB.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IDA:MGI.
DR   GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0045792; P:negative regulation of cell size; IMP:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; ISS:BHF-UCL.
DR   GO; GO:1901380; P:negative regulation of potassium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:1901017; P:negative regulation of potassium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; NAS:BHF-UCL.
DR   GO; GO:0060299; P:negative regulation of sarcomere organization; IMP:BHF-UCL.
DR   GO; GO:0051647; P:nucleus localization; IEA:Ensembl.
DR   GO; GO:0007009; P:plasma membrane organization; ISS:BHF-UCL.
DR   GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR   GO; GO:2001288; P:positive regulation of caveolin-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:BHF-UCL.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; ISS:BHF-UCL.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; IEA:Ensembl.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; NAS:BHF-UCL.
DR   GO; GO:0008104; P:protein localization; ISS:BHF-UCL.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0090279; P:regulation of calcium ion import; IDA:BHF-UCL.
DR   GO; GO:1901019; P:regulation of calcium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:1900825; P:regulation of membrane depolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0051394; P:regulation of nerve growth factor receptor activity; IMP:MGI.
DR   GO; GO:1900744; P:regulation of p38MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0038009; P:regulation of signal transduction by receptor internalization; IMP:MGI.
DR   GO; GO:0014819; P:regulation of skeletal muscle contraction; IMP:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0033292; P:T-tubule organization; TAS:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; ISS:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; ISS:BHF-UCL.
//
ID   CAYP1_HUMAN             Reviewed;         189 AA.
AC   Q13938; Q3MJA7; Q8WUZ3;
DE   RecName: Full=Calcyphosin;
DE   AltName: Full=Calcyphosine;
GN   Name=CAPS;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
//
ID   CAYP2_HUMAN             Reviewed;         557 AA.
AC   Q9BXY5; Q6PH84; Q8N242; Q8NAY5;
DE   RecName: Full=Calcyphosin-2;
DE   AltName: Full=Calcyphosine-2;
GN   Name=CAPS2; ORFNames=UG0636c06;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CAZA1_HUMAN             Reviewed;         286 AA.
AC   P52907; Q53FQ6; Q6FHD5;
DE   RecName: Full=F-actin-capping protein subunit alpha-1;
DE   AltName: Full=CapZ alpha-1;
GN   Name=CAPZA1;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   CAZA2_HUMAN             Reviewed;         286 AA.
AC   P47755; B4DG50;
DE   RecName: Full=F-actin-capping protein subunit alpha-2;
DE   AltName: Full=CapZ alpha-2;
GN   Name=CAPZA2;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   CAZA3_HUMAN             Reviewed;         299 AA.
AC   Q96KX2; Q969J0;
DE   RecName: Full=F-actin-capping protein subunit alpha-3;
DE   AltName: Full=CapZ alpha-3;
DE            Short=CP-alpha-3;
DE   AltName: Full=Germ cell-specific protein 3;
GN   Name=CAPZA3; Synonyms=CAPAA3, GSG3;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   CB015_HUMAN             Reviewed;         125 AA.
AC   Q8WU43;
DE   RecName: Full=Uncharacterized protein C2orf15;
GN   Name=C2orf15;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CB016_HUMAN             Reviewed;        1984 AA.
AC   Q68DN1; B9EIQ4; Q53S01; Q8ND64; Q9H088;
DE   RecName: Full=Uncharacterized protein C2orf16;
GN   Name=C2orf16;
//
ID   CB027_HUMAN             Reviewed;         203 AA.
AC   Q580R0; O43575; Q2M1X0; Q52M10; Q86XG2;
DE   RecName: Full=Uncharacterized protein C2orf27;
GN   Name=C2orf27A;
GN   and
GN   Name=C2orf27B;
//
ID   CB042_HUMAN             Reviewed;         574 AA.
AC   Q9NWW7; D6W5G3; Q9H629;
DE   RecName: Full=Uncharacterized protein C2orf42;
GN   Name=C2orf42;
//
ID   CB043_HUMAN             Reviewed;         325 AA.
AC   Q9H6V9; B7ZAJ5; D6W530; E7ESN0; Q53T37; Q53T58;
DE   RecName: Full=UPF0554 protein C2orf43;
GN   Name=C2orf43;
//
ID   CB044_HUMAN             Reviewed;         721 AA.
AC   Q9H6R7; D6W532; Q8IYK0; Q9HBP5;
DE   RecName: Full=WD repeat-containing protein C2orf44;
GN   Name=C2orf44; ORFNames=PP384;
//
ID   CB046_HUMAN             Reviewed;         139 AA.
AC   Q6ZSB3;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00299;
GN   Name=LINC00299; Synonyms=C2orf46, NCRNA00299;
//
ID   CB047_HUMAN             Reviewed;         291 AA.
AC   Q8WWC4; Q658V9; Q9H671;
DE   RecName: Full=Uncharacterized protein C2orf47, mitochondrial;
DE   Flags: Precursor;
GN   Name=C2orf47;
//
ID   CB050_HUMAN             Reviewed;         162 AA.
AC   Q96LR7; A8K9W3; D6W503;
DE   RecName: Full=Uncharacterized protein C2orf50;
GN   Name=C2orf50;
//
ID   CB052_HUMAN             Reviewed;         108 AA.
AC   Q8N535;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00471;
GN   Name=LINC00471; Synonyms=C2orf52;
//
ID   CB054_HUMAN             Reviewed;         447 AA.
AC   Q08AI8; B3KPP9; Q08AI9; Q53QU5; Q9H622;
DE   RecName: Full=Uncharacterized protein C2orf54;
GN   Name=C2orf54;
//
ID   CB057_HUMAN             Reviewed;         395 AA.
AC   Q53QW1; Q8N4F2;
DE   RecName: Full=Uncharacterized protein C2orf57;
GN   Name=C2orf57;
//
ID   CB048_HUMAN             Reviewed;         159 AA.
AC   Q96LS8;
DE   RecName: Full=Uncharacterized protein C2orf48;
GN   Name=C2orf48;
//
ID   CB061_HUMAN             Reviewed;         248 AA.
AC   Q8N801; H7C2Z2;
DE   RecName: Full=Uncharacterized protein C2orf61;
GN   Name=C2orf61;
//
ID   CB066_HUMAN             Reviewed;         117 AA.
AC   Q6UXQ4; B2RNW3;
DE   RecName: Full=Uncharacterized protein C2orf66;
DE   Flags: Precursor;
GN   Name=C2orf66; ORFNames=UNQ6411/PRO21186;
//
ID   CB069_HUMAN             Reviewed;         385 AA.
AC   Q8N8R5; Q8NE30;
DE   RecName: Full=UPF0565 protein C2orf69;
DE   Flags: Precursor;
GN   Name=C2orf69;
//
ID   CB068_HUMAN             Reviewed;         166 AA.
AC   Q2NKX9; B4DT10; Q4G0J7; Q6ZVA6;
DE   RecName: Full=UPF0561 protein C2orf68;
GN   Name=C2orf68;
//
ID   CB070_HUMAN             Reviewed;         201 AA.
AC   A6NJV1;
DE   RecName: Full=UPF0573 protein C2orf70;
GN   Name=C2orf70;
//
ID   CB071_HUMAN             Reviewed;        1288 AA.
AC   A6NGG8;
DE   RecName: Full=Uncharacterized protein C2orf71;
GN   Name=C2orf71;
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   CB072_HUMAN             Reviewed;         295 AA.
AC   A6NCS6;
DE   RecName: Full=Uncharacterized protein C2orf72;
GN   Name=C2orf72;
//
ID   CB073_HUMAN             Reviewed;         287 AA.
AC   Q8N5S3; A0AV79; A0AV81; Q8N7V4;
DE   RecName: Full=Uncharacterized protein C2orf73;
GN   Name=C2orf73;
//
ID   CB074_HUMAN             Reviewed;         194 AA.
AC   A8MZ97; C9JP62;
DE   RecName: Full=Uncharacterized protein C2orf74;
GN   Name=C2orf74;
//
ID   CB076_HUMAN             Reviewed;         126 AA.
AC   Q3KRA6; B7ZLS8; Q4VC35;
DE   RecName: Full=UPF0538 protein C2orf76;
GN   Name=C2orf76;
//
ID   CB078_HUMAN             Reviewed;         922 AA.
AC   A6NCI8;
DE   RecName: Full=Uncharacterized protein C2orf78;
GN   Name=C2orf78;
//
ID   CB080_HUMAN             Reviewed;         193 AA.
AC   Q0P641; A6NKZ3;
DE   RecName: Full=Uncharacterized protein C2orf80;
GN   Name=C2orf80;
//
ID   CB082_HUMAN             Reviewed;         121 AA.
AC   Q6UX34;
DE   RecName: Full=Uncharacterized protein C2orf82;
DE   Flags: Precursor;
GN   Name=C2orf82; ORFNames=UNQ830/PRO1757;
//
ID   CB083_HUMAN             Reviewed;         150 AA.
AC   Q53S99; A2RRG6; B8ZZI8; Q9NPW4;
DE   RecName: Full=Folate transporter-like protein C2orf83;
GN   Name=C2orf83;
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   CB091_HUMAN             Reviewed;         131 AA.
AC   Q6ZV80;
DE   RecName: Full=Uncharacterized protein C2orf91;
GN   Name=C2orf91;
//
ID   CB081_HUMAN             Reviewed;         581 AA.
AC   A6NN90;
DE   RecName: Full=Uncharacterized protein C2orf81;
GN   Name=C2orf81;
//
ID   CB39L_HUMAN             Reviewed;         337 AA.
AC   Q9H9S4; Q5TAW6; Q6WG71; Q96FG1; Q9BZ33;
DE   RecName: Full=Calcium-binding protein 39-like;
DE   AltName: Full=Antigen MLAA-34;
DE   AltName: Full=MO25beta;
DE   AltName: Full=Mo25-like protein;
GN   Name=CAB39L;
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
//
ID   CB5D1_HUMAN             Reviewed;         228 AA.
AC   Q6P9G0; D3DTQ8; Q96DM7;
DE   RecName: Full=Cytochrome b5 domain-containing protein 1;
GN   Name=CYB5D1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   CBG_HUMAN               Reviewed;         405 AA.
AC   P08185; A8K456; Q7Z2Q9;
DE   RecName: Full=Corticosteroid-binding globulin;
DE            Short=CBG;
DE   AltName: Full=Serpin A6;
DE   AltName: Full=Transcortin;
DE   Flags: Precursor;
GN   Name=SERPINA6; Synonyms=CBG;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0005496; F:steroid binding; IDA:UniProtKB.
DR   GO; GO:0008211; P:glucocorticoid metabolic process; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   CBLB_HUMAN              Reviewed;         982 AA.
AC   Q13191; A8K9S7; B7WNM4; Q13192; Q13193; Q3LIC0; Q63Z43; Q8IVC5;
DE   RecName: Full=E3 ubiquitin-protein ligase CBL-B;
DE            EC=6.3.2.-;
DE   AltName: Full=Casitas B-lineage lymphoma proto-oncogene b;
DE   AltName: Full=RING finger protein 56;
DE   AltName: Full=SH3-binding protein CBL-B;
DE   AltName: Full=Signal transduction protein CBL-B;
GN   Name=CBLB; Synonyms=RNF56; ORFNames=Nbla00127;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0002669; P:positive regulation of T cell anergy; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
//
ID   CBLC_HUMAN              Reviewed;         474 AA.
AC   Q9ULV8; Q8N1E5; Q9Y5Z2; Q9Y5Z3;
DE   RecName: Full=E3 ubiquitin-protein ligase CBL-C;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 57;
DE   AltName: Full=SH3-binding protein CBL-3;
DE   AltName: Full=SH3-binding protein CBL-C;
DE   AltName: Full=Signal transduction protein CBL-C;
GN   Name=CBLC; Synonyms=CBL3, RNF57;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.
DR   GO; GO:0001784; F:phosphotyrosine binding; IDA:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
//
ID   CBLN1_HUMAN             Reviewed;         193 AA.
AC   P23435; B2RAN9; P02682; Q52M09;
DE   RecName: Full=Cerebellin-1;
DE   AltName: Full=Precerebellin;
DE   Contains:
DE     RecName: Full=Cerebellin;
DE              Short=CER;
DE   Contains:
DE     RecName: Full=[des-Ser1]-cerebellin;
DE   Flags: Precursor;
GN   Name=CBLN1;
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0009306; P:protein secretion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   CBLN2_HUMAN             Reviewed;         224 AA.
AC   Q8IUK8; Q53Z56;
DE   RecName: Full=Cerebellin-2;
DE   Flags: Precursor;
GN   Name=CBLN2; ORFNames=UNQ1892/PRO4338;
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
//
ID   CBLN3_HUMAN             Reviewed;         205 AA.
AC   Q6UW01;
DE   RecName: Full=Cerebellin-3;
DE   Flags: Precursor;
GN   Name=CBLN3; ORFNames=UNQ755/PRO1486;
//
ID   CBLN4_HUMAN             Reviewed;         201 AA.
AC   Q9NTU7; A8K0S5;
DE   RecName: Full=Cerebellin-4;
DE   AltName: Full=Cerebellin-like glycoprotein 1;
DE   Flags: Precursor;
GN   Name=CBLN4; Synonyms=CBLNL1; ORFNames=UNQ718/PRO1382;
DR   GO; GO:0009306; P:protein secretion; IEA:Ensembl.
//
ID   CBL_HUMAN               Reviewed;         906 AA.
AC   P22681; A3KMP8;
DE   RecName: Full=E3 ubiquitin-protein ligase CBL;
DE            EC=6.3.2.-;
DE   AltName: Full=Casitas B-lineage lymphoma proto-oncogene;
DE   AltName: Full=Proto-oncogene c-Cbl;
DE   AltName: Full=RING finger protein 55;
DE   AltName: Full=Signal transduction protein CBL;
GN   Name=CBL; Synonyms=CBL2, RNF55;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:HGNC.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   CBPA1_HUMAN             Reviewed;         419 AA.
AC   P15085; A4D1M1; Q53XU0; Q9BS67; Q9UCF2;
DE   RecName: Full=Carboxypeptidase A1;
DE            EC=3.4.17.1;
DE   Flags: Precursor;
GN   Name=CPA1; Synonyms=CPA;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CBPA2_HUMAN             Reviewed;         419 AA.
AC   P48052; A4D1M4; C9JIK1; Q53XS1; Q96A12; Q96QN3; Q9UCF1;
DE   RecName: Full=Carboxypeptidase A2;
DE            EC=3.4.17.15;
DE   Flags: Precursor;
GN   Name=CPA2;
DR   GO; GO:0004180; F:carboxypeptidase activity; IDA:UniProtKB.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007039; P:vacuolar protein catabolic process; TAS:ProtInc.
//
ID   CBPA3_HUMAN             Reviewed;         417 AA.
AC   P15088; Q96E94;
DE   RecName: Full=Mast cell carboxypeptidase A;
DE            Short=MC-CPA;
DE            EC=3.4.17.1;
DE   AltName: Full=Carboxypeptidase A3;
DE   Flags: Precursor;
GN   Name=CPA3;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:UniProtKB.
//
ID   CBPA4_HUMAN             Reviewed;         421 AA.
AC   Q9UI42; B7Z576; Q86UY9;
DE   RecName: Full=Carboxypeptidase A4;
DE            EC=3.4.17.-;
DE   AltName: Full=Carboxypeptidase A3;
DE   Flags: Precursor;
GN   Name=CPA4; Synonyms=CPA3; ORFNames=UNQ694/PRO1339;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016573; P:histone acetylation; NAS:UniProtKB.
//
ID   CBPA5_HUMAN             Reviewed;         436 AA.
AC   Q8WXQ8; G3V0G8; Q6ZNI6; Q86SE2; Q86XM3; Q8NA08;
DE   RecName: Full=Carboxypeptidase A5;
DE            EC=3.4.17.-;
DE   Flags: Precursor;
GN   Name=CPA5;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPA6_HUMAN             Reviewed;         437 AA.
AC   Q8N4T0; Q8NEX8; Q8TDE8; Q9NRI9;
DE   RecName: Full=Carboxypeptidase A6;
DE            EC=3.4.17.-;
DE   Flags: Precursor;
GN   Name=CPA6; Synonyms=CPAH;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPB1_HUMAN             Reviewed;         417 AA.
AC   P15086; O60834; Q53XJ0; Q96BQ8;
DE   RecName: Full=Carboxypeptidase B;
DE            EC=3.4.17.2;
DE   AltName: Full=Pancreas-specific protein;
DE            Short=PASP;
DE   Flags: Precursor;
GN   Name=CPB1; Synonyms=CPB, PCPB;
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPB2_HUMAN             Reviewed;         423 AA.
AC   Q96IY4; A8K464; Q15114; Q5T9K1; Q5T9K2; Q9P2Y6;
DE   RecName: Full=Carboxypeptidase B2;
DE            EC=3.4.17.20;
DE   AltName: Full=Carboxypeptidase U;
DE            Short=CPU;
DE   AltName: Full=Plasma carboxypeptidase B;
DE            Short=pCPB;
DE   AltName: Full=Thrombin-activable fibrinolysis inhibitor;
DE            Short=TAFI;
DE   Flags: Precursor;
GN   Name=CPB2;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.
DR   GO; GO:0097421; P:liver regeneration; IEA:Ensembl.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IEA:Ensembl.
DR   GO; GO:2000346; P:negative regulation of hepatocyte proliferation; IEA:Ensembl.
DR   GO; GO:0010757; P:negative regulation of plasminogen activation; IEA:Ensembl.
DR   GO; GO:0003331; P:positive regulation of extracellular matrix constituent secretion; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
//
ID   CBPC1_HUMAN             Reviewed;        1226 AA.
AC   Q9UPW5; B4DIT6; B4DRZ8; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6;
AC   Q9H9W8; Q9NVK1;
DE   RecName: Full=Cytosolic carboxypeptidase 1;
DE            EC=3.4.17.-;
DE   AltName: Full=ATP/GTP-binding protein 1;
DE   AltName: Full=Nervous system nuclear protein induced by axotomy protein 1 homolog;
GN   Name=AGTPBP1; Synonyms=CCP1, KIAA1035, NNA1;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; ISS:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0035609; P:C-terminal protein deglutamylation; ISS:UniProtKB.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001754; P:eye photoreceptor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0050905; P:neuromuscular process; ISS:UniProtKB.
DR   GO; GO:0042133; P:neurotransmitter metabolic process; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; ISS:UniProtKB.
DR   GO; GO:0035610; P:protein side chain deglutamylation; ISS:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
//
ID   CBPC2_HUMAN             Reviewed;         902 AA.
AC   Q5U5Z8; A8MPX2; Q53FV5; Q8IV57; Q9H5C0;
DE   RecName: Full=Cytosolic carboxypeptidase 2;
DE            EC=3.4.17.-;
DE   AltName: Full=ATP/GTP-binding protein-like 2;
GN   Name=AGBL2; Synonyms=CCP2;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPC3_HUMAN             Reviewed;        1001 AA.
AC   Q8NEM8; B7Z827; Q9H965;
DE   RecName: Full=Cytosolic carboxypeptidase 3;
DE            EC=3.4.17.-;
DE   AltName: Full=ATP/GTP-binding protein-like 3;
GN   Name=AGBL3; Synonyms=CCP3;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPC4_HUMAN             Reviewed;        1066 AA.
AC   Q96MI9; A1A4X5; A6NJH6; C9JHL5;
DE   RecName: Full=Cytosolic carboxypeptidase 4;
DE            EC=3.4.17.-;
DE   AltName: Full=ATP/GTP-binding protein-like 1;
GN   Name=AGBL1; Synonyms=CCP4;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; ISS:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035609; P:C-terminal protein deglutamylation; ISS:UniProtKB.
DR   GO; GO:0035610; P:protein side chain deglutamylation; ISS:UniProtKB.
//
ID   CBPC5_HUMAN             Reviewed;         886 AA.
AC   Q8NDL9; A2VDI7; B7WPG9; B7Z7I7; D6W548; Q53SW0; Q53SZ0; Q96IK8;
AC   Q9H6V0; Q9H8P8;
DE   RecName: Full=Cytosolic carboxypeptidase-like protein 5;
DE            EC=3.4.17.-;
DE   AltName: Full=ATP/GTP-binding protein-like 5;
GN   Name=AGBL5; Synonyms=CCP5;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; ISS:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035611; P:protein branching point deglutamylation; ISS:UniProtKB.
DR   GO; GO:0035608; P:protein deglutamylation; ISS:UniProtKB.
//
ID   CBPC6_HUMAN             Reviewed;         503 AA.
AC   Q5VU57; B3KT26; B4DG37;
DE   RecName: Full=Cytosolic carboxypeptidase 6;
DE            EC=3.4.17.-;
DE   AltName: Full=ATP/GTP-binding protein-like 4;
GN   Name=AGBL4; Synonyms=CCP6;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; ISS:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035609; P:C-terminal protein deglutamylation; ISS:UniProtKB.
DR   GO; GO:0035610; P:protein side chain deglutamylation; ISS:UniProtKB.
//
ID   CBPD_HUMAN              Reviewed;        1380 AA.
AC   O75976; B7Z7T9; B7ZAU4; F5GZH6; O15377; Q86SH9; Q86XE6;
DE   RecName: Full=Carboxypeptidase D;
DE            EC=3.4.17.22;
DE   AltName: Full=Metallocarboxypeptidase D;
DE   AltName: Full=gp180;
DE   Flags: Precursor;
GN   Name=CPD;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0004185; F:serine-type carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPE_HUMAN              Reviewed;         476 AA.
AC   P16870; A8K4N1; B3KR42; B4DFN4; D3DP33; Q9UIU9;
DE   RecName: Full=Carboxypeptidase E;
DE            Short=CPE;
DE            EC=3.4.17.10;
DE   AltName: Full=Carboxypeptidase H;
DE            Short=CPH;
DE   AltName: Full=Enkephalin convertase;
DE   AltName: Full=Prohormone-processing carboxypeptidase;
DE   Flags: Precursor;
GN   Name=CPE;
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0042043; F:neurexin family protein binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0030070; P:insulin processing; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
DR   GO; GO:0072657; P:protein localization to membrane; IDA:BHF-UCL.
//
ID   CBPM_HUMAN              Reviewed;         443 AA.
AC   P14384; B2R800; Q9H2K9;
DE   RecName: Full=Carboxypeptidase M;
DE            Short=CPM;
DE            EC=3.4.17.12;
DE   Flags: Precursor;
GN   Name=CPM;
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
//
ID   CBPN_HUMAN              Reviewed;         458 AA.
AC   P15169; B1AP59;
DE   RecName: Full=Carboxypeptidase N catalytic chain;
DE            Short=CPN;
DE            EC=3.4.17.3;
DE   AltName: Full=Anaphylatoxin inactivator;
DE   AltName: Full=Arginine carboxypeptidase;
DE   AltName: Full=Carboxypeptidase N polypeptide 1;
DE   AltName: Full=Carboxypeptidase N small subunit;
DE   AltName: Full=Kininase-1;
DE   AltName: Full=Lysine carboxypeptidase;
DE   AltName: Full=Plasma carboxypeptidase B;
DE   AltName: Full=Serum carboxypeptidase N;
DE            Short=SCPN;
DE   Flags: Precursor;
GN   Name=CPN1; Synonyms=ACBP;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
//
ID   CBPO_HUMAN              Reviewed;         374 AA.
AC   Q8IVL8; Q2M277; Q7RTW7;
DE   RecName: Full=Carboxypeptidase O;
DE            Short=CPO;
DE            EC=3.4.17.-;
DE   Flags: Precursor;
GN   Name=CPO;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CBPQ_HUMAN              Reviewed;         472 AA.
AC   Q9Y646; B2RD88; Q8NBZ1; Q9UNM8; Q9Y5X6;
DE   RecName: Full=Carboxypeptidase Q;
DE            EC=3.4.17.-;
DE   AltName: Full=Lysosomal dipeptidase;
DE   AltName: Full=Plasma glutamate carboxypeptidase;
DE   Flags: Precursor;
GN   Name=CPQ; Synonyms=LCH1, PGCP;
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070573; F:metallodipeptidase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043171; P:peptide catabolic process; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0006590; P:thyroid hormone generation; ISS:UniProtKB.
DR   GO; GO:0042246; P:tissue regeneration; ISS:UniProtKB.
//
ID   CBPZ_HUMAN              Reviewed;         652 AA.
AC   Q66K79; O00520; Q96MX2;
DE   RecName: Full=Carboxypeptidase Z;
DE            Short=CPZ;
DE            EC=3.4.17.-;
DE   Flags: Precursor;
GN   Name=CPZ;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CBP_HUMAN               Reviewed;        2442 AA.
AC   Q92793; D3DUC9; O00147; Q16376; Q4LE28;
DE   RecName: Full=CREB-binding protein;
DE            EC=2.3.1.48;
GN   Name=CREBBP; Synonyms=CBP;
DR   GO; GO:0016407; F:acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0043426; F:MRF binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; TAS:BHF-UCL.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; TAS:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030718; P:germ-line stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0016573; P:histone acetylation; IDA:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CBR1_HUMAN              Reviewed;         277 AA.
AC   P16152; B2RBZ7; B4DFK7; Q3LHW8;
DE   RecName: Full=Carbonyl reductase [NADPH] 1;
DE            EC=1.1.1.184;
DE   AltName: Full=15-hydroxyprostaglandin dehydrogenase [NADP(+)];
DE            EC=1.1.1.197;
DE   AltName: Full=NADPH-dependent carbonyl reductase 1;
DE   AltName: Full=Prostaglandin 9-ketoreductase;
DE   AltName: Full=Prostaglandin-E(2) 9-reductase;
DE            EC=1.1.1.189;
GN   Name=CBR1; Synonyms=CBR, CRN;
DR   GO; GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0017144; P:drug metabolic process; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB.
//
ID   CBR3_HUMAN              Reviewed;         277 AA.
AC   O75828; Q6FHP2;
DE   RecName: Full=Carbonyl reductase [NADPH] 3;
DE            EC=1.1.1.184;
DE   AltName: Full=NADPH-dependent carbonyl reductase 3;
GN   Name=CBR3;
DR   GO; GO:0000253; F:3-keto sterol reductase activity; IEA:Ensembl.
DR   GO; GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0042376; P:phylloquinone catabolic process; IEA:Ensembl.
//
ID   CBR4_HUMAN              Reviewed;         237 AA.
AC   Q8N4T8; Q8WTW8; Q96K93;
DE   RecName: Full=Carbonyl reductase family member 4;
DE            EC=1.-.-.-;
DE   AltName: Full=3-oxoacyl-[acyl-carrier-protein] reductase;
DE            EC=1.1.1.-;
DE   AltName: Full=Quinone reductase CBR4;
GN   Name=CBR4;
DR   GO; GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; IDA:UniProtKB.
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0008753; F:NADPH dehydrogenase (quinone) activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IDA:UniProtKB.
DR   GO; GO:0044597; P:daunorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0044598; P:doxorubicin metabolic process; IMP:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
//
ID   CBS_HUMAN               Reviewed;         551 AA.
AC   P35520; B2R993; D3DSK4; Q99425; Q9BWC5;
DE   RecName: Full=Cystathionine beta-synthase;
DE            EC=4.2.1.22;
DE   AltName: Full=Beta-thionase;
DE   AltName: Full=Serine sulfhydrase;
GN   Name=CBS;
DR   GuidetoPHARMACOLOGY; 1443; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0004122; F:cystathionine beta-synthase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0021587; P:cerebellum morphogenesis; IEA:Ensembl.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   GO; GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0043418; P:homocysteine catabolic process; IDA:UniProtKB.
DR   GO; GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019448; P:L-cysteine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006563; P:L-serine metabolic process; IDA:UniProtKB.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:Ensembl.
DR   GO; GO:0030823; P:regulation of cGMP metabolic process; IEA:Ensembl.
DR   GO; GO:0043506; P:regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006801; P:superoxide metabolic process; IEA:Ensembl.
DR   GO; GO:0019346; P:transsulfuration; TAS:Reactome.
//
ID   CBWD1_HUMAN             Reviewed;         395 AA.
AC   Q9BRT8; A2RU55; A8K3N3; B0AZR4; Q49AJ1; Q5VVK2; Q6VBU6; Q7Z5Z0;
AC   Q7Z652; Q9BY38; Q9NYD0;
DE   RecName: Full=COBW domain-containing protein 1;
DE   AltName: Full=Cobalamin synthase W domain-containing protein 1;
DE            Short=COBP;
DE   AltName: Full=NPC-A-6 COBW domain-containing protein 1;
DE            Short=NPC-A-6;
GN   Name=CBWD1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   CBWD3_HUMAN             Reviewed;         395 AA.
AC   Q5JTY5;
DE   RecName: Full=COBW domain-containing protein 3;
DE   AltName: Full=Cobalamin synthase W domain-containing protein 3;
GN   Name=CBWD3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   CBWD2_HUMAN             Reviewed;         395 AA.
AC   Q8IUF1; Q0VAN3;
DE   RecName: Full=COBW domain-containing protein 2;
DE   AltName: Full=Cobalamin synthase W domain-containing protein 2;
GN   Name=CBWD2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   CBWD5_HUMAN             Reviewed;         395 AA.
AC   Q5RIA9; Q8N7U8;
DE   RecName: Full=COBW domain-containing protein 5;
DE   AltName: Full=Cobalamin synthase W domain-containing protein 5;
GN   Name=CBWD5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   CBWD6_HUMAN             Reviewed;         395 AA.
AC   Q4V339;
DE   RecName: Full=COBW domain-containing protein 6;
DE   AltName: Full=Cobalamin synthase W domain-containing protein 6;
GN   Name=CBWD6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   CBWD7_HUMAN             Reviewed;         247 AA.
AC   A6NM15;
DE   RecName: Full=Putative COBW domain-containing protein 7;
DE   AltName: Full=Putative cobalamin synthase W domain-containing protein 7;
GN   Name=CBWD7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   CBX1_HUMAN              Reviewed;         185 AA.
AC   P83916; P23197;
DE   RecName: Full=Chromobox protein homolog 1;
DE   AltName: Full=HP1Hsbeta;
DE   AltName: Full=Heterochromatin protein 1 homolog beta;
DE            Short=HP1 beta;
DE   AltName: Full=Heterochromatin protein p25;
DE   AltName: Full=M31;
DE   AltName: Full=Modifier 1 protein;
DE   AltName: Full=p25beta;
GN   Name=CBX1; Synonyms=CBX;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:1990226; F:histone methyltransferase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   CBX2_HUMAN              Reviewed;         532 AA.
AC   Q14781; Q0VDA5; Q9BTB1;
DE   RecName: Full=Chromobox protein homolog 2;
GN   Name=CBX2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0045137; P:development of primary sexual characteristics; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CBX3_HUMAN              Reviewed;         183 AA.
AC   Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6;
DE   RecName: Full=Chromobox protein homolog 3;
DE   AltName: Full=HECH;
DE   AltName: Full=Heterochromatin protein 1 homolog gamma;
DE            Short=HP1 gamma;
DE   AltName: Full=Modifier 2 protein;
GN   Name=CBX3;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:1990226; F:histone methyltransferase binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CBX4_HUMAN              Reviewed;         560 AA.
AC   O00257; B1PJR7; Q6TPI8; Q96C04;
DE   RecName: Full=E3 SUMO-protein ligase CBX4;
DE            EC=6.3.2.-;
DE   AltName: Full=Chromobox protein homolog 4;
DE   AltName: Full=Polycomb 2 homolog;
DE            Short=Pc2;
DE            Short=hPc2;
GN   Name=CBX4;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0032183; F:SUMO binding; IDA:MGI.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CBX5_HUMAN              Reviewed;         191 AA.
AC   P45973; B2R8T9;
DE   RecName: Full=Chromobox protein homolog 5;
DE   AltName: Full=Antigen p25;
DE   AltName: Full=Heterochromatin protein 1 homolog alpha;
DE            Short=HP1 alpha;
GN   Name=CBX5; Synonyms=HP1A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:1990226; F:histone methyltransferase binding; IPI:BHF-UCL.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; ISS:BHF-UCL.
DR   GO; GO:0070491; F:repressing transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CBX6_HUMAN              Reviewed;         412 AA.
AC   O95503; A8KAH0; Q96EM5;
DE   RecName: Full=Chromobox protein homolog 6;
GN   Name=CBX6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CBX7_HUMAN              Reviewed;         251 AA.
AC   O95931; Q86T17;
DE   RecName: Full=Chromobox protein homolog 7;
GN   Name=CBX7;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CBX8_HUMAN              Reviewed;         389 AA.
AC   Q9HC52; Q96H39; Q9NR07;
DE   RecName: Full=Chromobox protein homolog 8;
DE   AltName: Full=Polycomb 3 homolog;
DE            Short=Pc3;
DE            Short=hPc3;
DE   AltName: Full=Rectachrome 1;
GN   Name=CBX8; Synonyms=PC3, RC1;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0016574; P:histone ubiquitination; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CBY1_HUMAN              Reviewed;         126 AA.
AC   Q9Y3M2; B2R4S2; Q66GT6; Q9UIK9;
DE   RecName: Full=Protein chibby homolog 1;
DE   AltName: Full=ARPP-binding protein;
DE   AltName: Full=Cytosolic leucine-rich protein;
DE   AltName: Full=PIGEA-14;
DE   AltName: Full=PKD2 interactor, Golgi and endoplasmic reticulum-associated 1;
GN   Name=CBY1; Synonyms=ARB1, C22orf2, CBY, PGEA1; ORFNames=HRIHFB2025;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
//
ID   CBY3_HUMAN              Reviewed;         242 AA.
AC   A6NI87;
DE   RecName: Full=Protein chibby homolog 3;
GN   Name=CBY3;
//
ID   CC014_HUMAN             Reviewed;         128 AA.
AC   Q9HBI5; B2R9U0;
DE   RecName: Full=Uncharacterized protein C3orf14;
GN   Name=C3orf14; ORFNames=HT021;
//
ID   CC018_HUMAN             Reviewed;         162 AA.
AC   Q9UK00; C9JNP0;
DE   RecName: Full=Uncharacterized protein C3orf18;
DE   AltName: Full=Protein G20;
GN   Name=C3orf18;
//
ID   CC017_HUMAN             Reviewed;         567 AA.
AC   Q6NW34; D3DN69; Q68DM6; Q9H7U0; Q9UFM4;
DE   RecName: Full=Uncharacterized protein C3orf17;
GN   Name=C3orf17;
//
ID   CC020_HUMAN             Reviewed;         904 AA.
AC   Q8ND61; Q7L0U6; Q8NCP2; Q9H0I7;
DE   RecName: Full=Uncharacterized protein C3orf20;
GN   Name=C3orf20;
//
ID   CC022_HUMAN             Reviewed;         141 AA.
AC   Q8N5N4;
DE   RecName: Full=Uncharacterized protein C3orf22;
GN   Name=C3orf22;
//
ID   CC030_HUMAN             Reviewed;         536 AA.
AC   Q96M34; A1L4B7;
DE   RecName: Full=Uncharacterized protein C3orf30;
GN   Name=C3orf30;
//
ID   CC033_HUMAN             Reviewed;         294 AA.
AC   Q6P1S2; A8K1H5; Q86YE6; Q8IXA7; Q96NB5;
DE   RecName: Full=Protein C3orf33;
DE   AltName: Full=Protein AC3-33;
GN   Name=C3orf33; ORFNames=MSTP052;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
//
ID   CC038_HUMAN             Reviewed;         329 AA.
AC   Q5JPI3; B2R8X6; Q8TC85;
DE   RecName: Full=Uncharacterized protein C3orf38;
GN   Name=C3orf38;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   CC036_HUMAN             Reviewed;         165 AA.
AC   Q3SXR2; Q3SXR3; Q9H6K8;
DE   RecName: Full=Uncharacterized protein C3orf36;
GN   Name=C3orf36;
//
ID   CC049_HUMAN             Reviewed;         292 AA.
AC   Q96BT1;
DE   RecName: Full=Putative uncharacterized protein C3orf49;
GN   Name=C3orf49;
//
ID   CC055_HUMAN             Reviewed;         135 AA.
AC   A1A4F0; C9JP04; C9JXB5; Q8N6Q6;
DE   RecName: Full=Putative uncharacterized protein C3orf55;
GN   Name=C3orf55;
//
ID   CC056_HUMAN             Reviewed;         242 AA.
AC   Q8N813; B2RNW5;
DE   RecName: Full=Putative uncharacterized protein C3orf56;
GN   Name=C3orf56;
//
ID   CC062_HUMAN             Reviewed;         267 AA.
AC   Q6ZUJ4; Q6P7E9; Q7Z3X6;
DE   RecName: Full=Uncharacterized protein C3orf62;
GN   Name=C3orf62;
//
ID   CC065_HUMAN             Reviewed;         143 AA.
AC   Q96M15;
DE   RecName: Full=Putative uncharacterized protein C3orf65;
GN   Name=C3orf65;
//
ID   CC067_HUMAN             Reviewed;         689 AA.
AC   Q6ZVT6; B9EKV6; Q6ZV69;
DE   RecName: Full=Uncharacterized protein C3orf67;
GN   Name=C3orf67;
//
ID   CC070_HUMAN             Reviewed;         250 AA.
AC   A6NLC5; B2RNY2; B9EH83;
DE   RecName: Full=UPF0524 protein C3orf70;
GN   Name=C3orf70;
//
ID   CC072_HUMAN             Reviewed;         175 AA.
AC   Q6ZUU3; A6NGX0;
DE   RecName: Full=Uncharacterized protein C3orf72;
GN   Name=C3orf72;
//
ID   CC074_HUMAN             Reviewed;         163 AA.
AC   Q6ZRV3;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00696;
GN   Name=LINC00696; Synonyms=C3orf74;
//
ID   CC079_HUMAN             Reviewed;         100 AA.
AC   P0CE67;
DE   RecName: Full=Putative uncharacterized protein C3orf79;
GN   Name=C3orf79;
//
ID   CC080_HUMAN             Reviewed;         247 AA.
AC   F5H4A9; Q8N5S4;
DE   RecName: Full=Uncharacterized membrane protein C3orf80;
DE   Flags: Precursor;
GN   Name=C3orf80;
//
ID   CC083_HUMAN             Reviewed;         223 AA.
AC   H3BPM6;
DE   RecName: Full=Putative uncharacterized protein C3orf83;
DE   AltName: Full=MKRN2 antisense RNA 1;
DE   AltName: Full=MKRN2 antisense gene protein 1;
GN   Name=C3orf83; Synonyms=MKRN2-AS1;
//
ID   CC084_HUMAN             Reviewed;         204 AA.
AC   H3BNL1;
DE   RecName: Full=Uncharacterized protein C3orf84;
GN   Name=C3orf84;
//
ID   CC103_HUMAN             Reviewed;         242 AA.
AC   Q8IW40; A8K145; B8ZZU0;
DE   RecName: Full=Coiled-coil domain-containing protein 103;
GN   Name=CCDC103;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:BHF-UCL.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0003341; P:cilium movement; IGI:BHF-UCL.
DR   GO; GO:0071907; P:determination of digestive tract left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IC:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0036159; P:inner dynein arm assembly; IGI:BHF-UCL.
DR   GO; GO:0036158; P:outer dynein arm assembly; IGI:BHF-UCL.
//
ID   CC104_HUMAN             Reviewed;         342 AA.
AC   Q96G28; Q53SF0; Q53ST9; Q6UY34;
DE   RecName: Full=Coiled-coil domain-containing protein 104;
GN   Name=CCDC104; ORFNames=UNQ163/PRO189;
//
ID   CC105_HUMAN             Reviewed;         499 AA.
AC   Q8IYK2; Q8N7T5; Q8NDL5;
DE   RecName: Full=Coiled-coil domain-containing protein 105;
GN   Name=CCDC105;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   CC106_HUMAN             Reviewed;         280 AA.
AC   Q9BWC9; B3KUF9; D3K183; Q99786;
DE   RecName: Full=Coiled-coil domain-containing protein 106;
GN   Name=CCDC106;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CC107_HUMAN             Reviewed;         283 AA.
AC   Q8WV48; A6XND6; Q5T4R5; Q5T4R8; Q5T4R9; Q86VB6; Q8N2E4;
DE   RecName: Full=Coiled-coil domain-containing protein 107;
DE   Flags: Precursor;
GN   Name=CCDC107; ORFNames=PSEC0222;
//
ID   CC108_HUMAN             Reviewed;        1925 AA.
AC   Q6ZU64; A2BDD8; E9PCR1; Q6ZSR8; Q8N0T4; Q8NDJ3;
DE   RecName: Full=Coiled-coil domain-containing protein 108;
GN   Name=CCDC108;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   CC110_HUMAN             Reviewed;         833 AA.
AC   Q8TBZ0; Q86YI9; Q8N7W0;
DE   RecName: Full=Coiled-coil domain-containing protein 110;
DE   AltName: Full=Cancer/testis antigen 52;
DE            Short=CT52;
DE   AltName: Full=Cancer/testis antigen KM-HN-1;
GN   Name=CCDC110; Synonyms=KMHN1;
//
ID   CC112_HUMAN             Reviewed;         446 AA.
AC   Q8NEF3; Q6A334;
DE   RecName: Full=Coiled-coil domain-containing protein 112;
DE   AltName: Full=Mutated in bladder cancer protein 1;
GN   Name=CCDC112; Synonyms=MBC1;
//
ID   CC113_HUMAN             Reviewed;         377 AA.
AC   Q9H0I3; B2RAQ7; B4DR20; Q9NZX2;
DE   RecName: Full=Coiled-coil domain-containing protein 113;
GN   Name=CCDC113; ORFNames=HSPC065;
//
ID   CC114_HUMAN             Reviewed;         670 AA.
AC   Q96M63; Q6ZRL4; Q96M06; Q9UFG8;
DE   RecName: Full=Coiled-coil domain-containing protein 114;
GN   Name=CCDC114;
DR   GO; GO:0036158; P:outer dynein arm assembly; IMP:UniProtKB.
//
ID   CC115_HUMAN             Reviewed;         180 AA.
AC   Q96NT0; Q9BR88;
DE   RecName: Full=Coiled-coil domain-containing protein 115;
GN   Name=CCDC115;
//
ID   CC116_HUMAN             Reviewed;         515 AA.
AC   Q8IYX3; Q8N9Y9;
DE   RecName: Full=Coiled-coil domain-containing protein 116;
GN   Name=CCDC116;
//
ID   CC117_HUMAN             Reviewed;         279 AA.
AC   Q8IWD4; A8K0F1; B7Z2V1; B7Z860; Q6ICA7; Q8N278;
DE   RecName: Full=Coiled-coil domain-containing protein 117;
GN   Name=CCDC117;
//
ID   CC120_HUMAN             Reviewed;         630 AA.
AC   Q96HB5; B4DFC1; B4DTU2; F5GZU4;
DE   RecName: Full=Coiled-coil domain-containing protein 120;
GN   Name=CCDC120; ORFNames=JM11;
//
ID   CC122_HUMAN             Reviewed;         273 AA.
AC   Q5T0U0; B2RP70; B7ZMI9; Q96MV0;
DE   RecName: Full=Coiled-coil domain-containing protein 122;
GN   Name=CCDC122;
//
ID   CC121_HUMAN             Reviewed;         278 AA.
AC   Q6ZUS5; B3KW66; J3KQZ8; Q9H8G6;
DE   RecName: Full=Coiled-coil domain-containing protein 121;
GN   Name=CCDC121;
//
ID   CC124_HUMAN             Reviewed;         223 AA.
AC   Q96CT7;
DE   RecName: Full=Coiled-coil domain-containing protein 124;
GN   Name=CCDC124;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   CC125_HUMAN             Reviewed;         511 AA.
AC   Q86Z20; Q86Z19;
DE   RecName: Full=Coiled-coil domain-containing protein 125;
DE   AltName: Full=Protein kenae;
GN   Name=CCDC125; Synonyms=KENAE;
//
ID   CC126_HUMAN             Reviewed;         140 AA.
AC   Q96EE4; A8K1J6; Q6UWP1; Q75MQ6;
DE   RecName: Full=Coiled-coil domain-containing protein 126;
DE   Flags: Precursor;
GN   Name=CCDC126; ORFNames=UNQ786/PRO1605;
DR   GO; GO:0030144; F:alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; IEA:InterPro.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IEA:InterPro.
//
ID   CC129_HUMAN             Reviewed;        1044 AA.
AC   Q6ZRS4; A2RU17; B3KTI9; B4DHB0; B4E2R1; F5H3V5;
DE   RecName: Full=Coiled-coil domain-containing protein 129;
GN   Name=CCDC129;
//
ID   CC127_HUMAN             Reviewed;         260 AA.
AC   Q96BQ5;
DE   RecName: Full=Coiled-coil domain-containing protein 127;
GN   Name=CCDC127;
//
ID   CC130_HUMAN             Reviewed;         396 AA.
AC   P13994; Q9BQ72;
DE   RecName: Full=Coiled-coil domain-containing protein 130;
DE   AltName: Full=9 kDa protein;
GN   Name=CCDC130; ORFNames=SB115;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   CC132_HUMAN             Reviewed;         964 AA.
AC   Q96JG6; B3KX22; D1MQ00; F5H5U7; Q75N07; Q8WVK3; Q9H5C6;
DE   RecName: Full=Coiled-coil domain-containing protein 132;
GN   Name=CCDC132; Synonyms=KIAA1861;
//
ID   CC134_HUMAN             Reviewed;         229 AA.
AC   Q9H6E4;
DE   RecName: Full=Coiled-coil domain-containing protein 134;
DE   Flags: Precursor;
GN   Name=CCDC134;
//
ID   CC135_HUMAN             Reviewed;         874 AA.
AC   Q8IY82; A8K943; Q8NAA0; Q9H080;
DE   RecName: Full=Coiled-coil domain-containing protein lobo homolog;
DE   AltName: Full=Coiled-coil domain-containing protein 135;
GN   Name=CCDC135; Synonyms=C16orf50;
DR   GO; GO:0097588; P:archaeal or bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CC136_HUMAN             Reviewed;        1154 AA.
AC   Q96JN2; A4D1K1; A7MCY7; A8MYA7; Q6ZVK7; Q9H8M3; Q9UFE1;
DE   RecName: Full=Coiled-coil domain-containing protein 136;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 6 protein;
GN   Name=CCDC136; Synonyms=KIAA1793; ORFNames=NAG6;
//
ID   CC137_HUMAN             Reviewed;         289 AA.
AC   Q6PK04;
DE   RecName: Full=Coiled-coil domain-containing protein 137;
GN   Name=CCDC137;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CC138_HUMAN             Reviewed;         665 AA.
AC   Q96M89; Q05DF1; Q4ZG07; Q53TE1; Q6ZUY5; Q86VL7;
DE   RecName: Full=Coiled-coil domain-containing protein 138;
GN   Name=CCDC138;
//
ID   CC140_HUMAN             Reviewed;         163 AA.
AC   Q96MF4;
DE   RecName: Full=Coiled-coil domain-containing protein 140;
GN   Name=CCDC140;
//
ID   CC141_HUMAN             Reviewed;         875 AA.
AC   Q6ZP82; Q8N8H3;
DE   RecName: Full=Coiled-coil domain-containing protein 141;
GN   Name=CCDC141;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CC142_HUMAN             Reviewed;         750 AA.
AC   Q17RM4; B7ZKV5; Q8NBJ3; Q8NBV2; Q96KA7;
DE   RecName: Full=Coiled-coil domain-containing protein 142;
GN   Name=CCDC142; ORFNames=PSEC0243;
//
ID   CC147_HUMAN             Reviewed;         872 AA.
AC   Q5T655; D3DRA6; Q8NA27;
DE   RecName: Full=Coiled-coil domain-containing protein 147;
GN   Name=CCDC147; Synonyms=C10orf80;
//
ID   CC146_HUMAN             Reviewed;         955 AA.
AC   Q8IYE0; A8K8X6; Q9P223;
DE   RecName: Full=Coiled-coil domain-containing protein 146;
GN   Name=CCDC146; Synonyms=KIAA1505;
//
ID   CC148_HUMAN             Reviewed;         591 AA.
AC   Q8NFR7; F5H839; Q3B7I3; Q3B7I4; Q3KR41; Q4ZG12; Q4ZG23; Q53TM6;
AC   Q96BN5; Q96LM2;
DE   RecName: Full=Coiled-coil domain-containing protein 148;
GN   Name=CCDC148;
//
ID   CC149_HUMAN             Reviewed;         474 AA.
AC   Q6ZUS6; A6NJE7; B4DK90; B4DZG3; G5EA04; Q6NW41; Q8N3K8;
DE   RecName: Full=Coiled-coil domain-containing protein 149;
GN   Name=CCDC149;
//
ID   CC14A_HUMAN             Reviewed;         594 AA.
AC   Q9UNH5; A6MA65; B1AQ14; B1AQ15; O43171; O60727; O60728; Q52LH9;
AC   Q8IXX0;
DE   RecName: Full=Dual specificity protein phosphatase CDC14A;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=CDC14 cell division cycle 14 homolog A;
GN   Name=CDC14A;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
//
ID   CC14B_HUMAN             Reviewed;         498 AA.
AC   O60729; A6N5X8; A8MQ20; B1AL31; B1AL32; O43183; O60730; Q5JU08;
DE   RecName: Full=Dual specificity protein phosphatase CDC14B;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=CDC14 cell division cycle 14 homolog B;
GN   Name=CDC14B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0051488; P:activation of anaphase-promoting complex activity; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.
//
ID   CC14C_HUMAN             Reviewed;         554 AA.
AC   A4D256; Q2VIP7; Q6NUS3; Q8NCT2;
DE   RecName: Full=Dual specificity protein phosphatase CDC14C;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=CDC14 cell division cycle 14 homolog C;
GN   Name=CDC14C; Synonyms=CDC14B2;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
//
ID   CC150_HUMAN             Reviewed;        1101 AA.
AC   Q8NCX0; Q6P5U6; Q6P663; Q8N8V5;
DE   RecName: Full=Coiled-coil domain-containing protein 150;
GN   Name=CCDC150;
//
ID   CC151_HUMAN             Reviewed;         595 AA.
AC   A5D8V7; Q96CG5;
DE   RecName: Full=Coiled-coil domain-containing protein 151;
GN   Name=CCDC151;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CC152_HUMAN             Reviewed;         254 AA.
AC   Q4G0S7; B3KXI4; Q5BLP6;
DE   RecName: Full=Coiled-coil domain-containing protein 152;
GN   Name=CCDC152; ORFNames=Chr5_400;
//
ID   CC153_HUMAN             Reviewed;         210 AA.
AC   Q494R4;
DE   RecName: Full=Coiled-coil domain-containing protein 153;
GN   Name=CCDC153;
//
ID   CC154_HUMAN             Reviewed;         674 AA.
AC   A6NI56; G9JV18;
DE   RecName: Full=Coiled-coil domain-containing protein 154;
GN   Name=CCDC154;
//
ID   CC157_HUMAN             Reviewed;         752 AA.
AC   Q569K6; Q0VD76; Q9BYA4;
DE   RecName: Full=Coiled-coil domain-containing protein 157;
GN   Name=CCDC157; Synonyms=KIAA1656;
//
ID   CC159_HUMAN             Reviewed;         412 AA.
AC   P0C7I6; B4DEG3; B4DWR8; B4E133; B7ZAM4;
DE   RecName: Full=Coiled-coil domain-containing protein 159;
GN   Name=CCDC159;
//
ID   CC160_HUMAN             Reviewed;         325 AA.
AC   A6NGH7;
DE   RecName: Full=Coiled-coil domain-containing protein 160;
GN   Name=CCDC160;
//
ID   CC162_HUMAN             Reviewed;         907 AA.
AC   A2VCL2; A1A4V1; A4QMU0; Q5JSU0; Q5JSU7;
DE   RecName: Full=Coiled-coil domain-containing protein 162;
DE   AltName: Full=Coiled-coil domain-containing protein 162 pseudogene;
GN   Name=CCDC162P; Synonyms=C6orf184, C6orf185, CCDC162;
//
ID   CC166_HUMAN             Reviewed;         439 AA.
AC   P0CW27;
DE   RecName: Full=Coiled-coil domain-containing protein 166;
GN   Name=CCDC166;
//
ID   CC167_HUMAN             Reviewed;          97 AA.
AC   Q9P0B6; Q5T7F7; Q9BTQ9;
DE   RecName: Full=Coiled-coil domain-containing protein 167;
GN   Name=CCDC167; Synonyms=C6orf129; ORFNames=HSPC265;
//
ID   CC169_HUMAN             Reviewed;         214 AA.
AC   A6NNP5; A6NC13; A6NCT2; B7ZW45; B7ZW49; B9EJF2; Q9H1T4; Q9H1T5;
DE   RecName: Full=Coiled-coil domain-containing protein 169;
GN   Name=CCDC169; Synonyms=C13orf38;
//
ID   CC170_HUMAN             Reviewed;         715 AA.
AC   Q8IYT3; Q5VXB7; Q6P9E4; Q96KA9; Q9H5M3;
DE   RecName: Full=Coiled-coil domain-containing protein 170;
GN   Name=CCDC170; Synonyms=C6orf97;
//
ID   CC168_HUMAN             Reviewed;        2452 AA.
AC   Q8NDH2; Q8N800;
DE   RecName: Full=Coiled-coil domain-containing protein 168;
GN   Name=CCDC168; Synonyms=C13orf40;
//
ID   CC171_HUMAN             Reviewed;        1326 AA.
AC   Q6TFL3; B7ZM22; Q5SU58; Q6P1W1; Q6ZR13; Q8N1Z4; Q8N8L3; Q8TBR2;
DE   RecName: Full=Coiled-coil domain-containing protein 171;
GN   Name=CCDC171; Synonyms=C9orf93;
//
ID   CC172_HUMAN             Reviewed;         258 AA.
AC   P0C7W6;
DE   RecName: Full=Coiled-coil domain-containing protein 172;
GN   Name=CCDC172; Synonyms=C10orf96;
//
ID   CC173_HUMAN             Reviewed;         552 AA.
AC   Q0VFZ6; Q6PJF6;
DE   RecName: Full=Coiled-coil domain-containing protein 173;
GN   Name=CCDC173; Synonyms=C2orf77;
//
ID   CC174_HUMAN             Reviewed;         467 AA.
AC   Q6PII3; Q96CS5;
DE   RecName: Full=Coiled-coil domain-containing protein 174;
GN   Name=CCDC174; Synonyms=C3orf19;
//
ID   CC175_HUMAN             Reviewed;         793 AA.
AC   P0C221; G3V5J7;
DE   RecName: Full=Coiled-coil domain-containing protein 175;
GN   Name=CCDC175; Synonyms=C14orf38;
//
ID   CC177_HUMAN             Reviewed;         707 AA.
AC   Q9NQR7; B2R5G1; Q2M359;
DE   RecName: Full=Coiled-coil domain-containing protein 177;
DE   AltName: Full=Myelin proteolipid protein-like protein;
GN   Name=CCDC177; Synonyms=C14orf162, PLPL;
//
ID   CC178_HUMAN             Reviewed;         867 AA.
AC   Q5BJE1; A6NDC6; J3KS92; Q6ZP67; Q6ZU20;
DE   RecName: Full=Coiled-coil domain-containing protein 178;
GN   Name=CCDC178; Synonyms=C18orf34;
//
ID   CC180_HUMAN             Reviewed;        1646 AA.
AC   Q9P1Z9; Q2KHR6; Q5VV25; Q68DP5; Q69YV9; Q6AHY0;
DE   RecName: Full=Coiled-coil domain-containing protein 180;
GN   Name=CCDC180; Synonyms=C9orf174, KIAA1529;
//
ID   CC179_HUMAN             Reviewed;          68 AA.
AC   H3BU77;
DE   RecName: Full=Coiled-coil domain-containing protein 179;
GN   Name=CCDC179;
//
ID   CC181_HUMAN             Reviewed;         509 AA.
AC   Q5TID7; O60780; Q53FD5; Q5TID9; Q8TC48;
DE   RecName: Full=Coiled-coil domain-containing protein 181;
GN   Name=CCDC181; Synonyms=C1orf114;
//
ID   CC182_HUMAN             Reviewed;         153 AA.
AC   A6NF36;
DE   RecName: Full=Coiled-coil domain-containing protein 182;
GN   Name=CCDC182;
DR   GO; GO:0008585; P:female gonad development; ISS:UniProtKB.
//
ID   CC183_HUMAN             Reviewed;         534 AA.
AC   Q5T5S1; B2RP89; C9JD38; Q6P2D9; Q8NAI4; Q8TF18;
DE   RecName: Full=Coiled-coil domain-containing protein 183;
GN   Name=CCDC183; Synonyms=KIAA1984;
//
ID   CC184_HUMAN             Reviewed;         194 AA.
AC   Q52MB2; Q96MK5; Q96N39;
DE   RecName: Full=Coiled-coil domain-containing protein 184;
GN   Name=CCDC184; Synonyms=C12orf68;
//
ID   CC185_HUMAN             Reviewed;         623 AA.
AC   Q8N715; Q8N746; Q8NA93;
DE   RecName: Full=Coiled-coil domain-containing protein 185;
GN   Name=CCDC185; Synonyms=C1orf65;
//
ID   CC28A_HUMAN             Reviewed;         274 AA.
AC   Q8IWP9; E1P591; Q32NC7; Q66K67; Q96E23; Q9Y430;
DE   RecName: Full=Coiled-coil domain-containing protein 28A;
DE   AltName: Full=CCRL1AP;
GN   Name=CCDC28A; Synonyms=C6orf80;
//
ID   CC28B_HUMAN             Reviewed;         200 AA.
AC   Q9BUN5; A8K789; Q8TBV8;
DE   RecName: Full=Coiled-coil domain-containing protein 28B;
GN   Name=CCDC28B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
//
ID   CC42B_HUMAN             Reviewed;         308 AA.
AC   A6NFT4;
DE   RecName: Full=Coiled-coil domain-containing protein 42B;
GN   Name=CCDC42B;
//
ID   CC4L_HUMAN              Reviewed;          92 AA.
AC   Q8NHW4; B2RUZ3; B7ZMA8; Q50EM1; Q50EM2; Q50EM3; Q50EM4; Q50EM5;
AC   Q50EM6; Q50EM7; Q50EM8; Q569J2; Q6NSB0;
DE   RecName: Full=C-C motif chemokine 4-like;
DE   AltName: Full=Lymphocyte activation gene 1 protein;
DE            Short=LAG-1;
DE   AltName: Full=Macrophage inflammatory protein 1-beta;
DE            Short=MIP-1-beta;
DE   AltName: Full=Monocyte adherence-induced protein 5-alpha;
DE   AltName: Full=Small-inducible cytokine A4-like;
DE   Flags: Precursor;
GN   Name=CCL4L1; Synonyms=CCL4L, LAG1, SCYA4L1;
GN   and
GN   Name=CCL4L2; Synonyms=CCL4L, SCYA4L2;
DR   GO; GO:0060326; P:cell chemotaxis; IEA:GOC.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
//
ID   CC50A_HUMAN             Reviewed;         361 AA.
AC   Q9NV96; A8K9V8; E1P539; Q658Z3; Q96H09; Q9NSL9;
DE   RecName: Full=Cell cycle control protein 50A;
DE   AltName: Full=Transmembrane protein 30A;
GN   Name=TMEM30A; Synonyms=C6orf67, CDC50A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045332; P:phospholipid translocation; IEA:Ensembl.
DR   GO; GO:0070863; P:positive regulation of protein exit from endoplasmic reticulum; IDA:UniProtKB.
DR   GO; GO:0036010; P:protein localization to endosome; IMP:UniProtKB.
//
ID   CC50B_HUMAN             Reviewed;         351 AA.
AC   Q3MIR4; B3KR84; Q14D00;
DE   RecName: Full=Cell cycle control protein 50B;
DE   AltName: Full=Transmembrane protein 30B;
GN   Name=TMEM30B; Synonyms=CDC50B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070863; P:positive regulation of protein exit from endoplasmic reticulum; IDA:UniProtKB.
//
ID   CC50C_HUMAN             Reviewed;         113 AA.
AC   A0ZSE6;
DE   RecName: Full=Cell cycle control protein 50C;
DE   AltName: Full=Transmembrane protein 30C;
GN   Name=TMEM30C; Synonyms=CDC50C;
//
ID   CC74A_HUMAN             Reviewed;         378 AA.
AC   Q96AQ1; Q6P4I5;
DE   RecName: Full=Coiled-coil domain-containing protein 74A;
GN   Name=CCDC74A;
//
ID   CC74B_HUMAN             Reviewed;         380 AA.
AC   Q96LY2; Q6NW18;
DE   RecName: Full=Coiled-coil domain-containing protein 74B;
GN   Name=CCDC74B;
//
ID   CC71L_HUMAN             Reviewed;         235 AA.
AC   Q8N9Z2; Q7Z756;
DE   RecName: Full=Coiled-coil domain-containing protein 71L;
GN   Name=CCDC71L; Synonyms=C7orf74;
//
ID   CC85B_HUMAN             Reviewed;         202 AA.
AC   Q15834; B2R598; Q96HA0;
DE   RecName: Full=Coiled-coil domain-containing protein 85B;
DE   AltName: Full=Hepatitis delta antigen-interacting protein A;
DE            Short=Delta-interacting protein A;
GN   Name=CCDC85B; Synonyms=DIPA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CC85A_HUMAN             Reviewed;         553 AA.
AC   Q96PX6;
DE   RecName: Full=Coiled-coil domain-containing protein 85A;
GN   Name=CCDC85A; Synonyms=KIAA1912;
//
ID   CC85C_HUMAN             Reviewed;         419 AA.
AC   A6NKD9;
DE   RecName: Full=Coiled-coil domain-containing protein 85C;
GN   Name=CCDC85C;
DR   GO; GO:0021987; P:cerebral cortex development; ISS:UniProtKB.
//
ID   CC88B_HUMAN             Reviewed;        1476 AA.
AC   A6NC98; A5D8Y5; B5MDM2; Q05BL2; Q6RUV3; Q8N1Q6; Q8NF44; Q9H0H1;
DE   RecName: Full=Coiled-coil domain-containing protein 88B;
DE   AltName: Full=Brain leucine zipper domain-containing protein;
DE   AltName: Full=Hook-related protein 3;
DE            Short=HkRP3;
GN   Name=CCDC88B; Synonyms=BRLZ;
//
ID   CC90B_HUMAN             Reviewed;         254 AA.
AC   Q9GZT6; A8K8I4; B4E3L2; Q3B781; Q9GZU6;
DE   RecName: Full=Coiled-coil domain-containing protein 90B, mitochondrial;
DE   Flags: Precursor;
GN   Name=CCDC90B; ORFNames=CUA003, MDS011, MDS025;
//
ID   CCAR1_HUMAN             Reviewed;        1150 AA.
AC   Q8IX12; A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; Q32NE3; Q5EBM3;
AC   Q5VUP6; Q6PIZ0; Q6X935; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6;
DE   RecName: Full=Cell division cycle and apoptosis regulator protein 1;
DE   AltName: Full=Cell cycle and apoptosis regulatory protein 1;
DE            Short=CARP-1;
DE   AltName: Full=Death inducer with SAP domain;
GN   Name=CCAR1; Synonyms=CARP1, DIS;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IGI:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CCAR2_HUMAN             Reviewed;         923 AA.
AC   Q8N163; A6NL03; B2RB79; D3DSR6; Q6P0Q9; Q8N3G7; Q8N8M1; Q8TF34;
AC   Q9H9Q9; Q9HD12; Q9NT55;
DE   RecName: Full=Cell cycle and apoptosis regulator protein 2;
DE   AltName: Full=Cell division cycle and apoptosis regulator protein 2;
DE   AltName: Full=DBIRD complex subunit KIAA1967;
DE   AltName: Full=Deleted in breast cancer gene 1 protein;
DE            Short=DBC-1;
DE            Short=DBC.1;
DE   AltName: Full=p30 DBC;
GN   Name=CCAR2; Synonyms=DBC1, KIAA1967;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000003; P:positive regulation of DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IMP:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
//
ID   CCB42_HUMAN             Reviewed;          81 AA.
AC   Q1T7F1;
DE   RecName: Full=Putative chemokine-related protein B42;
//
ID   CCBE1_HUMAN             Reviewed;         406 AA.
AC   Q6UXH8; Q6MZX5; Q86SS2; Q8TF19;
DE   RecName: Full=Collagen and calcium-binding EGF domain-containing protein 1;
DE   AltName: Full=Full of fluid protein homolog;
DE   Flags: Precursor;
GN   Name=CCBE1; Synonyms=KIAA1983; ORFNames=UNQ1921/PRO4395;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005518; F:collagen binding; IDA:MGI.
DR   GO; GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0048845; P:venous blood vessel morphogenesis; ISS:UniProtKB.
//
ID   CCD11_HUMAN             Reviewed;         514 AA.
AC   Q96M91; B4DXT1;
DE   RecName: Full=Coiled-coil domain-containing protein 11;
GN   Name=CCDC11;
//
ID   CCD12_HUMAN             Reviewed;         166 AA.
AC   Q8WUD4; Q8N8I4;
DE   RecName: Full=Coiled-coil domain-containing protein 12;
GN   Name=CCDC12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CCD13_HUMAN             Reviewed;         715 AA.
AC   Q8IYE1;
DE   RecName: Full=Coiled-coil domain-containing protein 13;
GN   Name=CCDC13;
//
ID   CCD14_HUMAN             Reviewed;         953 AA.
AC   Q49A88; B7Z2T2; B8ZZ41; B8ZZ58; D3DN98; Q7Z3N3; Q86T30; Q8IWF8;
AC   Q8WUJ8; Q96K47; Q9H9A3; Q9UFH0;
DE   RecName: Full=Coiled-coil domain-containing protein 14;
GN   Name=CCDC14;
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   CCD15_HUMAN             Reviewed;         951 AA.
AC   Q0P6D6; Q9H8U7;
DE   RecName: Full=Coiled-coil domain-containing protein 15;
GN   Name=CCDC15;
//
ID   CCD17_HUMAN             Reviewed;         622 AA.
AC   Q96LX7; A1A4Y7; B4DNX7; B4E1Q5; C9J8L2; Q0P683; Q5T629;
DE   RecName: Full=Coiled-coil domain-containing protein 17;
GN   Name=CCDC17;
//
ID   CCD18_HUMAN             Reviewed;        1454 AA.
AC   Q5T9S5; Q6ZU17;
DE   RecName: Full=Coiled-coil domain-containing protein 18;
DE   AltName: Full=Sarcoma antigen NY-SAR-24;
GN   Name=CCDC18;
//
ID   CCD19_HUMAN             Reviewed;         551 AA.
AC   Q9UL16; Q5VU18;
DE   RecName: Full=Coiled-coil domain-containing protein 19, mitochondrial;
DE   AltName: Full=Nasopharyngeal epithelium-specific protein 1;
DE   Flags: Precursor;
GN   Name=CCDC19; Synonyms=NESG1;
//
ID   CCD22_HUMAN             Reviewed;         627 AA.
AC   O60826; A8K7G1;
DE   RecName: Full=Coiled-coil domain-containing protein 22;
GN   Name=CCDC22; Synonyms=CXorf37; ORFNames=JM1;
//
ID   CCD23_HUMAN             Reviewed;          66 AA.
AC   Q8N300; A8K5P1; D3DPW7;
DE   RecName: Full=Coiled-coil domain-containing protein 23;
GN   Name=CCDC23;
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IGI:MGI.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:MGI.
DR   GO; GO:0009306; P:protein secretion; IDA:MGI.
//
ID   CCD24_HUMAN             Reviewed;         307 AA.
AC   Q8N4L8; Q6RWT2;
DE   RecName: Full=Coiled-coil domain-containing protein 24;
GN   Name=CCDC24;
//
ID   CCD25_HUMAN             Reviewed;         208 AA.
AC   Q86WR0; Q96SI2; Q9NV98;
DE   RecName: Full=Coiled-coil domain-containing protein 25;
GN   Name=CCDC25;
//
ID   CCD26_HUMAN             Reviewed;         109 AA.
AC   Q8TAB7;
DE   RecName: Full=Putative coiled-coil domain-containing protein 26;
DE   AltName: Full=Retinoic acid modulator;
GN   Name=CCDC26; Synonyms=RAM;
//
ID   CCD27_HUMAN             Reviewed;         656 AA.
AC   Q2M243; Q5TBV3; Q96M50;
DE   RecName: Full=Coiled-coil domain-containing protein 27;
GN   Name=CCDC27;
//
ID   CCD30_HUMAN             Reviewed;         783 AA.
AC   Q5VVM6; Q14F06; Q5VVM5;
DE   RecName: Full=Coiled-coil domain-containing protein 30;
DE   AltName: Full=Prefoldin subunit 6-like protein;
GN   Name=CCDC30; Synonyms=PFDN6L;
//
ID   CCD33_HUMAN             Reviewed;         958 AA.
AC   Q8N5R6; A8K3U4; A8MPQ6; A8MV61; A8MVU9; B3KQ49; Q8TAX6; Q9H5Q6;
DE   RecName: Full=Coiled-coil domain-containing protein 33;
DE   AltName: Full=Cancer/testis antigen 61;
DE            Short=CT61;
GN   Name=CCDC33;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CCD34_HUMAN             Reviewed;         373 AA.
AC   Q96HJ3; B2R8G2; Q8IX69; Q9H2A6; Q9Y599;
DE   RecName: Full=Coiled-coil domain-containing protein 34;
DE   AltName: Full=Renal carcinoma antigen NY-REN-41;
GN   Name=CCDC34; Synonyms=RAMA3; ORFNames=L15;
//
ID   CCD36_HUMAN             Reviewed;         594 AA.
AC   Q8IYA8; C9JJL0; Q05DG9; Q96LP7;
DE   RecName: Full=Coiled-coil domain-containing protein 36;
DE   AltName: Full=Cancer/testis antigen 74;
DE            Short=CT74;
GN   Name=CCDC36;
//
ID   CCD37_HUMAN             Reviewed;         611 AA.
AC   Q494V2; D3DNA8; Q494V1; Q494V4; Q8N838;
DE   RecName: Full=Coiled-coil domain-containing protein 37;
GN   Name=CCDC37;
//
ID   CCD38_HUMAN             Reviewed;         563 AA.
AC   Q502W7; Q8N835;
DE   RecName: Full=Coiled-coil domain-containing protein 38;
GN   Name=CCDC38;
//
ID   CCD39_HUMAN             Reviewed;         941 AA.
AC   Q9UFE4; B4E2H1;
DE   RecName: Full=Coiled-coil domain-containing protein 39;
GN   Name=CCDC39;
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IMP:UniProtKB.
DR   GO; GO:0071907; P:determination of digestive tract left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0071910; P:determination of liver left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0035469; P:determination of pancreatic left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IMP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IMP:BHF-UCL.
//
ID   CCD40_HUMAN             Reviewed;        1142 AA.
AC   Q4G0X9; A8MTD2; C9JTI9; C9JTJ0; C9JXW1; Q6PE47; Q9HCD2; Q9NWL5;
DE   RecName: Full=Coiled-coil domain-containing protein 40;
GN   Name=CCDC40; Synonyms=KIAA1640;
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.
DR   GO; GO:0071907; P:determination of digestive tract left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0071910; P:determination of liver left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0035469; P:determination of pancreatic left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0003351; P:epithelial cilium movement; IMP:BHF-UCL.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IMP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IMP:BHF-UCL.
DR   GO; GO:0003356; P:regulation of cilium beat frequency; IMP:BHF-UCL.
//
ID   CCD42_HUMAN             Reviewed;         316 AA.
AC   Q96M95; Q8N6Q0;
DE   RecName: Full=Coiled-coil domain-containing protein 42A;
GN   Name=CCDC42; Synonyms=CCDC42A;
//
ID   CCD43_HUMAN             Reviewed;         224 AA.
AC   Q96MW1; C9JVK9;
DE   RecName: Full=Coiled-coil domain-containing protein 43;
GN   Name=CCDC43;
//
ID   CCD47_HUMAN             Reviewed;         483 AA.
AC   Q96A33; B2RAS8; D3DU20; Q96D00; Q96JZ7; Q9H3E4; Q9NRG3;
DE   RecName: Full=Coiled-coil domain-containing protein 47;
DE   Flags: Precursor;
GN   Name=CCDC47; ORFNames=GK001, MSTP041, PSEC0077;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006983; P:ER overload response; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
//
ID   CCD50_HUMAN             Reviewed;         306 AA.
AC   Q8IVM0; Q86VH7;
DE   RecName: Full=Coiled-coil domain-containing protein 50;
DE   AltName: Full=Protein Ymer;
GN   Name=CCDC50; Synonyms=C3orf6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CCD51_HUMAN             Reviewed;         411 AA.
AC   Q96ER9; Q9HA01;
DE   RecName: Full=Coiled-coil domain-containing protein 51;
GN   Name=CCDC51;
//
ID   CCD53_HUMAN             Reviewed;         194 AA.
AC   Q9Y3C0; B2RC74; Q53FF0; Q6IAI4; Q96QK0;
DE   RecName: Full=WASH complex subunit CCDC53;
DE   AltName: Full=Coiled-coil domain-containing protein 53;
GN   Name=CCDC53; ORFNames=AD-016, CGI-116, x0009;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CCD54_HUMAN             Reviewed;         328 AA.
AC   Q8NEL0; Q96A43;
DE   RecName: Full=Coiled-coil domain-containing protein 54;
DE   AltName: Full=Testis development protein NYD-SP17;
GN   Name=CCDC54;
//
ID   CCD57_HUMAN             Reviewed;         916 AA.
AC   Q2TAC2; A6NP51; A8MQC7; Q8IWG2; Q8TER3;
DE   RecName: Full=Coiled-coil domain-containing protein 57;
GN   Name=CCDC57;
//
ID   CCD58_HUMAN             Reviewed;         144 AA.
AC   Q4VC31; Q32LY6;
DE   RecName: Full=Coiled-coil domain-containing protein 58;
GN   Name=CCDC58;
//
ID   CCD60_HUMAN             Reviewed;         550 AA.
AC   Q8IWA6;
DE   RecName: Full=Coiled-coil domain-containing protein 60;
GN   Name=CCDC60;
//
ID   CCD61_HUMAN             Reviewed;         512 AA.
AC   Q9Y6R9; C8CAP4; Q9HDB6;
DE   RecName: Full=Coiled-coil domain-containing protein 61;
GN   Name=CCDC61;
//
ID   CCD62_HUMAN             Reviewed;         684 AA.
AC   Q6P9F0; A8K8V1; B3KUP3; Q6ZVF2; Q86VJ0; Q9BYZ5;
DE   RecName: Full=Coiled-coil domain-containing protein 62;
DE   AltName: Full=Protein TSP-NY;
DE   AltName: Full=Protein aaa;
GN   Name=CCDC62;
//
ID   CCD63_HUMAN             Reviewed;         563 AA.
AC   Q8NA47; B4DY03; Q0P603; Q6P2E1;
DE   RecName: Full=Coiled-coil domain-containing protein 63;
GN   Name=CCDC63;
//
ID   CCD65_HUMAN             Reviewed;         484 AA.
AC   Q8IXS2; A6NJG5; B2RBE2; Q8N7G4; Q8NA91; Q96JA0;
DE   RecName: Full=Coiled-coil domain-containing protein 65;
DE   AltName: Full=Testis development protein NYD-SP28;
GN   Name=CCDC65;
//
ID   CCD66_HUMAN             Reviewed;         948 AA.
AC   A2RUB6; B3KWL8; Q4VC34; Q8N949;
DE   RecName: Full=Coiled-coil domain-containing protein 66;
GN   Name=CCDC66;
DR   GO; GO:0060060; P:post-embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0046548; P:retinal rod cell development; IEA:Ensembl.
//
ID   CCD68_HUMAN             Reviewed;         335 AA.
AC   Q9H2F9; B2R9I3;
DE   RecName: Full=Coiled-coil domain-containing protein 68;
DE   AltName: Full=Cutaneous T-cell lymphoma-associated antigen se57-1;
DE            Short=CTCL-associated antigen se57-1;
GN   Name=CCDC68;
//
ID   CCD69_HUMAN             Reviewed;         296 AA.
AC   A6NI79; A8K9X6;
DE   RecName: Full=Coiled-coil domain-containing protein 69;
GN   Name=CCDC69;
//
ID   CCD70_HUMAN             Reviewed;         233 AA.
AC   Q6NSX1; Q8N7A8; Q9H097;
DE   RecName: Full=Coiled-coil domain-containing protein 70;
DE   Flags: Precursor;
GN   Name=CCDC70;
//
ID   CCD71_HUMAN             Reviewed;         467 AA.
AC   Q8IV32; Q6IPE2; Q9H8H4; Q9H9F1;
DE   RecName: Full=Coiled-coil domain-containing protein 71;
GN   Name=CCDC71;
//
ID   CCD73_HUMAN             Reviewed;        1079 AA.
AC   Q6ZRK6; Q6P5Q7; Q6ZMW0; Q86WE7;
DE   RecName: Full=Coiled-coil domain-containing protein 73;
DE   AltName: Full=Sarcoma antigen NY-SAR-79;
GN   Name=CCDC73;
//
ID   CCD77_HUMAN             Reviewed;         488 AA.
AC   Q9BR77; B4DDE8;
DE   RecName: Full=Coiled-coil domain-containing protein 77;
GN   Name=CCDC77;
//
ID   CCD78_HUMAN             Reviewed;         438 AA.
AC   A2IDD5; B4DNY4; B4E1U6; Q05BY7; Q05CA0; Q6T2V5; Q6ZR33; Q8IUR3;
AC   Q8NAY7; Q96S12;
DE   RecName: Full=Coiled-coil domain-containing protein 78;
DE   AltName: Full=hsCCDC78;
GN   Name=CCDC78; Synonyms=C16orf25; ORFNames=JFP10;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0098535; P:de novo centriole assembly; IDA:UniProtKB.
DR   GO; GO:0003009; P:skeletal muscle contraction; IMP:UniProtKB.
//
ID   CCD80_HUMAN             Reviewed;         950 AA.
AC   Q76M96; D3DN67; Q5PR20; Q6GPG9; Q8IVT6; Q8NBV1; Q8NHY8;
DE   RecName: Full=Coiled-coil domain-containing protein 80;
DE   AltName: Full=Down-regulated by oncogenes protein 1;
DE   AltName: Full=Up-regulated in BRS-3 deficient mouse homolog;
DE   Flags: Precursor;
GN   Name=CCDC80; Synonyms=DRO1, URB; ORFNames=HBE245;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   CCD81_HUMAN             Reviewed;         652 AA.
AC   Q6ZN84; A0AVL7; Q53FW3; Q9H5E5;
DE   RecName: Full=Coiled-coil domain-containing protein 81;
GN   Name=CCDC81;
//
ID   CCD82_HUMAN             Reviewed;         544 AA.
AC   Q8N4S0; B3KPU7; Q8WV71; Q9H2Q5; Q9H5E3;
DE   RecName: Full=Coiled-coil domain-containing protein 82;
GN   Name=CCDC82; ORFNames=HT025;
//
ID   CCD83_HUMAN             Reviewed;         413 AA.
AC   Q8IWF9; B2RA49; Q6X7T2; Q6ZVT5; Q8N9Y1;
DE   RecName: Full=Coiled-coil domain-containing protein 83;
GN   Name=CCDC83; ORFNames=HSD9;
//
ID   CCD84_HUMAN             Reviewed;         332 AA.
AC   Q86UT8;
DE   RecName: Full=Coiled-coil domain-containing protein 84;
GN   Name=CCDC84; ORFNames=DLNB14;
//
ID   CCD86_HUMAN             Reviewed;         360 AA.
AC   Q9H6F5;
DE   RecName: Full=Coiled-coil domain-containing protein 86;
DE   AltName: Full=Cytokine-induced protein with coiled-coil domain;
GN   Name=CCDC86; Synonyms=CYCLON;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CCD87_HUMAN             Reviewed;         849 AA.
AC   Q9NVE4; Q8NE76;
DE   RecName: Full=Coiled-coil domain-containing protein 87;
GN   Name=CCDC87;
DR   GO; GO:0000910; P:cytokinesis; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   CCD89_HUMAN             Reviewed;         374 AA.
AC   Q8N998;
DE   RecName: Full=Coiled-coil domain-containing protein 89;
DE   AltName: Full=Bc8 orange-interacting protein;
GN   Name=CCDC89; Synonyms=BOIP;
//
ID   CCD91_HUMAN             Reviewed;         441 AA.
AC   Q7Z6B0; B3KSA3; C9JR07; Q68D43; Q6IA78; Q8NEN7; Q9NUW9;
DE   RecName: Full=Coiled-coil domain-containing protein 91;
DE   AltName: Full=GGA-binding partner;
DE   AltName: Full=p56 accessory protein;
GN   Name=CCDC91; Synonyms=GGABP; ORFNames=HSD8;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   CCD92_HUMAN             Reviewed;         331 AA.
AC   Q53HC0; Q9H697;
DE   RecName: Full=Coiled-coil domain-containing protein 92;
DE   AltName: Full=Limkain beta-2;
GN   Name=CCDC92;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   CCD93_HUMAN             Reviewed;         631 AA.
AC   Q567U6; A8K3V7; Q4LE78; Q53TJ2; Q8TBX5; Q9H6R5; Q9NV15;
DE   RecName: Full=Coiled-coil domain-containing protein 93;
GN   Name=CCDC93;
//
ID   CCD94_HUMAN             Reviewed;         323 AA.
AC   Q9BW85; O75270; Q9H862; Q9NW16;
DE   RecName: Full=Coiled-coil domain-containing protein 94;
GN   Name=CCDC94;
//
ID   CCD96_HUMAN             Reviewed;         555 AA.
AC   Q2M329; Q8N2I7;
DE   RecName: Full=Coiled-coil domain-containing protein 96;
GN   Name=CCDC96;
//
ID   CCD97_HUMAN             Reviewed;         343 AA.
AC   Q96F63; Q658N6; Q96IF3;
DE   RecName: Full=Coiled-coil domain-containing protein 97;
GN   Name=CCDC97;
//
ID   CCDB1_HUMAN             Reviewed;         360 AA.
AC   O95273; A8K3Q0; A8K3U2; Q6ZQN9; Q7Z519; Q8NBS7; Q8NBY2; Q9NS19;
AC   Q9NYH3; Q9UHX9;
DE   RecName: Full=Cyclin-D1-binding protein 1;
DE   AltName: Full=Grap2 and cyclin-D-interacting protein;
DE   AltName: Full=Human homolog of Maid;
GN   Name=CCNDBP1; Synonyms=DIP1, GCIP, HHM;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   CCDC6_HUMAN             Reviewed;         474 AA.
AC   Q16204; Q15250; Q6GSG7;
DE   RecName: Full=Coiled-coil domain-containing protein 6;
DE   AltName: Full=Papillary thyroid carcinoma-encoded protein;
DE   AltName: Full=Protein H4;
GN   Name=CCDC6; Synonyms=D10S170, TST1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
//
ID   CCDC3_HUMAN             Reviewed;         270 AA.
AC   Q9BQI4; Q5VYV8; Q5VYV9;
DE   RecName: Full=Coiled-coil domain-containing protein 3;
DE   AltName: Full=Fat/vessel-derived secretory protein;
DE            Short=Favine;
DE   Flags: Precursor;
GN   Name=CCDC3;
//
ID   CCDC7_HUMAN             Reviewed;         486 AA.
AC   Q96M83; Q5VW55; Q8IVQ0; Q8NEQ0;
DE   RecName: Full=Coiled-coil domain-containing protein 7;
DE   AltName: Full=Protein BIOT2;
GN   Name=CCDC7; Synonyms=BIOT2;
//
ID   CCDC8_HUMAN             Reviewed;         538 AA.
AC   Q9H0W5; Q8TB26;
DE   RecName: Full=Coiled-coil domain-containing protein 8;
GN   Name=CCDC8;
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   CCDC9_HUMAN             Reviewed;         531 AA.
AC   Q9Y3X0;
DE   RecName: Full=Coiled-coil domain-containing protein 9;
GN   Name=CCDC9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CCER1_HUMAN             Reviewed;         406 AA.
AC   Q8TC90; Q8TC47;
DE   RecName: Full=Coiled-coil domain-containing glutamate-rich protein 1;
GN   Name=CCER1; Synonyms=C12orf12;
//
ID   CCER2_HUMAN             Reviewed;         266 AA.
AC   I3L3R5;
DE   RecName: Full=Coiled-coil domain-containing glutamate-rich protein 2;
DE   Flags: Precursor;
GN   Name=CCER2;
//
ID   CCG1_HUMAN              Reviewed;         222 AA.
AC   Q06432; B2R9N3; Q14D59;
DE   RecName: Full=Voltage-dependent calcium channel gamma-1 subunit;
DE   AltName: Full=Dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma;
GN   Name=CACNG1; Synonyms=CACNLG;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0070296; P:sarcoplasmic reticulum calcium ion transport; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CCG2_HUMAN              Reviewed;         323 AA.
AC   Q9Y698; Q2M1M1; Q5TGT3; Q9UGZ7;
DE   RecName: Full=Voltage-dependent calcium channel gamma-2 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-2 subunit;
DE   AltName: Full=Transmembrane AMPAR regulatory protein gamma-2;
DE            Short=TARP gamma-2;
GN   Name=CACNG2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CCG3_HUMAN              Reviewed;         315 AA.
AC   O60359;
DE   RecName: Full=Voltage-dependent calcium channel gamma-3 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-3 subunit;
DE   AltName: Full=Transmembrane AMPAR regulatory protein gamma-3;
DE            Short=TARP gamma-3;
GN   Name=CACNG3;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; NAS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   CCG4_HUMAN              Reviewed;         327 AA.
AC   Q9UBN1; B2RCK0;
DE   RecName: Full=Voltage-dependent calcium channel gamma-4 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-4 subunit;
DE   AltName: Full=Transmembrane AMPAR regulatory protein gamma-4;
DE            Short=TARP gamma-4;
GN   Name=CACNG4;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0051899; P:membrane depolarization; TAS:Reactome.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CCG5_HUMAN              Reviewed;         275 AA.
AC   Q9UF02; A8K2A6; Q547R3; Q8WXS7; Q9UHM3;
DE   RecName: Full=Voltage-dependent calcium channel gamma-5 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-5 subunit;
DE   AltName: Full=Transmembrane AMPAR regulatory protein gamma-5;
DE            Short=TARP gamma-5;
GN   Name=CACNG5;
DR   GO; GO:0015075; F:ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CCG6_HUMAN              Reviewed;         260 AA.
AC   Q9BXT2;
DE   RecName: Full=Voltage-dependent calcium channel gamma-6 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-6 subunit;
GN   Name=CACNG6;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; NAS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
//
ID   CCG7_HUMAN              Reviewed;         275 AA.
AC   P62955; Q52LL8; Q8VBX3; Q8WXS6; Q9BXT1;
DE   RecName: Full=Voltage-dependent calcium channel gamma-7 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-7 subunit;
DE   AltName: Full=Transmembrane AMPAR regulatory protein gamma-7;
DE            Short=TARP gamma-7;
GN   Name=CACNG7;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; NAS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
//
ID   CCG8_HUMAN              Reviewed;         425 AA.
AC   Q8WXS5; Q9BXT0; Q9BY23;
DE   RecName: Full=Voltage-dependent calcium channel gamma-8 subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-8 subunit;
DE   AltName: Full=Transmembrane AMPAR regulatory protein gamma-8;
DE            Short=TARP gamma-8;
GN   Name=CACNG8; Synonyms=CACNG6;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; NAS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   CCGL_HUMAN              Reviewed;         190 AA.
AC   Q8WXS4;
DE   RecName: Full=Voltage-dependent calcium channel gamma-like subunit;
DE   AltName: Full=Neuronal voltage-gated calcium channel gamma-like subunit;
DE   AltName: Full=Transmembrane protein 37;
GN   Name=TMEM37; Synonyms=PR;
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
//
ID   CCHCR_HUMAN             Reviewed;         782 AA.
AC   Q8TD31; A2ABH6; E9PE84; Q2TB67; Q5SQ82; Q5STE9; Q9NRK8; Q9NWY9;
AC   Q9NXJ4; Q9NXK3; Q9Y6W1; Q9Y6W2;
DE   RecName: Full=Coiled-coil alpha-helical rod protein 1;
DE   AltName: Full=Alpha-helical coiled-coil rod protein;
DE   AltName: Full=Putative gene 8 protein;
DE            Short=Pg8;
GN   Name=CCHCR1; Synonyms=C6orf18, HCR;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
//
ID   CCHL_HUMAN              Reviewed;         268 AA.
AC   P53701; B3KUS1; Q502X8;
DE   RecName: Full=Cytochrome c-type heme lyase;
DE            Short=CCHL;
DE            EC=4.4.1.17;
DE   AltName: Full=Holocytochrome c-type synthase;
GN   Name=HCCS; Synonyms=CCHL;
DR   GO; GO:0004408; F:holocytochrome-c synthase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:ProtInc.
//
ID   CCKAR_HUMAN             Reviewed;         428 AA.
AC   P32238; B2R9Z5;
DE   RecName: Full=Cholecystokinin receptor type A;
DE            Short=CCK-A receptor;
DE            Short=CCK-AR;
DE   AltName: Full=Cholecystokinin-1 receptor;
DE            Short=CCK1-R;
GN   Name=CCKAR; Synonyms=CCKRA;
DR   GuidetoPHARMACOLOGY; 76; -.
DR   GO; GO:0004951; F:cholecystokinin receptor activity; TAS:ProtInc.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0038188; P:cholecystokinin signaling pathway; TAS:GOC.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
//
ID   CCKN_HUMAN              Reviewed;         115 AA.
AC   P06307;
DE   RecName: Full=Cholecystokinin;
DE            Short=CCK;
DE   Contains:
DE     RecName: Full=Cholecystokinin-58;
DE              Short=CCK58;
DE   Contains:
DE     RecName: Full=Cholecystokinin-58 desnonopeptide;
DE     AltName: Full=(1-49)-CCK58;
DE   Contains:
DE     RecName: Full=Cholecystokinin-39;
DE              Short=CCK39;
DE   Contains:
DE     RecName: Full=Cholecystokinin-33;
DE              Short=CCK33;
DE   Contains:
DE     RecName: Full=Cholecystokinin-25;
DE              Short=CCK25;
DE   Contains:
DE     RecName: Full=Cholecystokinin-18;
DE              Short=CCK18;
DE   Contains:
DE     RecName: Full=Cholecystokinin-12;
DE              Short=CCK12;
DE   Contains:
DE     RecName: Full=Cholecystokinin-8;
DE              Short=CCK8;
DE   Contains:
DE     RecName: Full=Cholecystokinin-7;
DE              Short=CCK7;
DE   Contains:
DE     RecName: Full=Cholecystokinin-5;
DE              Short=CCK5;
DE   Flags: Precursor;
GN   Name=CCK;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005184; F:neuropeptide hormone activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; ISS:UniProtKB.
DR   GO; GO:0032099; P:negative regulation of appetite; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL11_HUMAN             Reviewed;          97 AA.
AC   P51671; P50877; Q92490; Q92491;
DE   RecName: Full=Eotaxin;
DE   AltName: Full=C-C motif chemokine 11;
DE   AltName: Full=Eosinophil chemotactic protein;
DE   AltName: Full=Small-inducible cytokine A11;
DE   Flags: Precursor;
GN   Name=CCL11; Synonyms=SCYA11;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0060763; P:mammary duct terminal end bud growth; IEA:Ensembl.
DR   GO; GO:0002551; P:mast cell chemotaxis; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0070670; P:response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; TAS:ProtInc.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL13_HUMAN             Reviewed;          98 AA.
AC   Q99616; O95689; Q6ICQ6;
DE   RecName: Full=C-C motif chemokine 13;
DE   AltName: Full=CK-beta-10;
DE   AltName: Full=Monocyte chemoattractant protein 4;
DE   AltName: Full=Monocyte chemotactic protein 4;
DE            Short=MCP-4;
DE   AltName: Full=NCC-1;
DE   AltName: Full=Small-inducible cytokine A13;
DE   Contains:
DE     RecName: Full=C-C motif chemokine 13, long chain;
DE   Contains:
DE     RecName: Full=C-C motif chemokine 13, medium chain;
DE   Contains:
DE     RecName: Full=C-C motif chemokine 13, short chain;
DE   Flags: Precursor;
GN   Name=CCL13; Synonyms=MCP4, NCC1, SCYA13;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL14_HUMAN             Reviewed;          93 AA.
AC   Q16627; E1P649; E1P650; Q13954;
DE   RecName: Full=C-C motif chemokine 14;
DE   AltName: Full=Chemokine CC-1/CC-3;
DE            Short=HCC-1/HCC-3;
DE   AltName: Full=HCC-1(1-74);
DE   AltName: Full=NCC-2;
DE   AltName: Full=Small-inducible cytokine A14;
DE   Contains:
DE     RecName: Full=HCC-1(3-74);
DE   Contains:
DE     RecName: Full=HCC-1(4-74);
DE   Contains:
DE     RecName: Full=HCC-1(9-74);
DE   Flags: Precursor;
GN   Name=CCL14; Synonyms=NCC2, SCYA14;
DR   GO; GO:0060326; P:cell chemotaxis; IEA:GOC.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   CCL16_HUMAN             Reviewed;         120 AA.
AC   O15467; Q4KKU0;
DE   RecName: Full=C-C motif chemokine 16;
DE   AltName: Full=Chemokine CC-4;
DE            Short=HCC-4;
DE   AltName: Full=Chemokine LEC;
DE   AltName: Full=IL-10-inducible chemokine;
DE   AltName: Full=LCC-1;
DE   AltName: Full=Liver-expressed chemokine;
DE   AltName: Full=Lymphocyte and monocyte chemoattractant;
DE            Short=LMC;
DE   AltName: Full=Monotactin-1;
DE            Short=MTN-1;
DE   AltName: Full=NCC-4;
DE   AltName: Full=Small-inducible cytokine A16;
DE   Flags: Precursor;
GN   Name=CCL16; Synonyms=ILINCK, NCC4, SCYA16;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007154; P:cell communication; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
//
ID   CCL15_HUMAN             Reviewed;         113 AA.
AC   Q16663; B2RU34; E1P651; Q9UM74;
DE   RecName: Full=C-C motif chemokine 15;
DE   AltName: Full=Chemokine CC-2;
DE            Short=HCC-2;
DE   AltName: Full=Leukotactin-1;
DE            Short=LKN-1;
DE   AltName: Full=MIP-1 delta;
DE   AltName: Full=Macrophage inflammatory protein 5;
DE            Short=MIP-5;
DE   AltName: Full=Mrp-2b;
DE   AltName: Full=NCC-3;
DE   AltName: Full=Small-inducible cytokine A15;
DE   Contains:
DE     RecName: Full=CCL15(22-92);
DE   Contains:
DE     RecName: Full=CCL15(25-92);
DE   Contains:
DE     RecName: Full=CCL15(29-92);
DE   Flags: Precursor;
GN   Name=CCL15; Synonyms=MIP5, NCC3, SCYA15;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL17_HUMAN             Reviewed;          94 AA.
AC   Q92583; A0N0Q9; Q2M287;
DE   RecName: Full=C-C motif chemokine 17;
DE   AltName: Full=CC chemokine TARC;
DE   AltName: Full=Small-inducible cytokine A17;
DE   AltName: Full=Thymus and activation-regulated chemokine;
DE   Flags: Precursor;
GN   Name=CCL17; Synonyms=SCYA17, TARC;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   CCL18_HUMAN             Reviewed;          89 AA.
AC   P55774; B5BUM2; Q53X71;
DE   RecName: Full=C-C motif chemokine 18;
DE   AltName: Full=Alternative macrophage activation-associated CC chemokine 1;
DE            Short=AMAC-1;
DE   AltName: Full=CC chemokine PARC;
DE   AltName: Full=Dendritic cell chemokine 1;
DE            Short=DC-CK1;
DE   AltName: Full=Macrophage inflammatory protein 4;
DE            Short=MIP-4;
DE   AltName: Full=Pulmonary and activation-regulated chemokine;
DE   AltName: Full=Small-inducible cytokine A18;
DE   Contains:
DE     RecName: Full=CCL18(1-68);
DE   Contains:
DE     RecName: Full=CCL18(3-69);
DE   Contains:
DE     RecName: Full=CCL18(4-69);
DE   Flags: Precursor;
GN   Name=CCL18; Synonyms=AMAC1, DCCK1, MIP4, PARC, SCYA18;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007154; P:cell communication; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL1_HUMAN              Reviewed;          96 AA.
AC   P22362; B2R5G9; Q2M309;
DE   RecName: Full=C-C motif chemokine 1;
DE   AltName: Full=Small-inducible cytokine A1;
DE   AltName: Full=T lymphocyte-secreted protein I-309;
DE   Flags: Precursor;
GN   Name=CCL1; Synonyms=SCYA1;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:ProtInc.
//
ID   CCL19_HUMAN             Reviewed;          98 AA.
AC   Q99731; O00697; O00736;
DE   RecName: Full=C-C motif chemokine 19;
DE   AltName: Full=Beta-chemokine exodus-3;
DE   AltName: Full=CK beta-11;
DE   AltName: Full=Epstein-Barr virus-induced molecule 1 ligand chemokine;
DE            Short=EBI1 ligand chemokine;
DE            Short=ELC;
DE   AltName: Full=Macrophage inflammatory protein 3 beta;
DE            Short=MIP-3-beta;
DE   AltName: Full=Small-inducible cytokine A19;
DE   Flags: Precursor;
GN   Name=CCL19; Synonyms=ELC, MIP3B, SCYA19;
DR   GO; GO:0048020; F:CCR chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0031735; F:CCR10 chemokine receptor binding; IDA:BHF-UCL.
DR   GO; GO:0031732; F:CCR7 chemokine receptor binding; ISS:BHF-UCL.
DR   GO; GO:0008009; F:chemokine activity; IDA:BHF-UCL.
DR   GO; GO:0042379; F:chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; ISS:BHF-UCL.
DR   GO; GO:0007154; P:cell communication; TAS:ProtInc.
DR   GO; GO:0048469; P:cell maturation; ISS:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0001768; P:establishment of T cell polarity; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0001771; P:immunological synapse formation; ISS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; NAS:BHF-UCL.
DR   GO; GO:0072610; P:interleukin-12 secretion; ISS:BHF-UCL.
DR   GO; GO:0097029; P:mature dendritic cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0002408; P:myeloid dendritic cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:2000107; P:negative regulation of leukocyte apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:BHF-UCL.
DR   GO; GO:2000147; P:positive regulation of cell motility; IDA:BHF-UCL.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.
DR   GO; GO:2000549; P:positive regulation of dendritic cell dendrite assembly; ISS:BHF-UCL.
DR   GO; GO:0045807; P:positive regulation of endocytosis; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0010560; P:positive regulation of glycoprotein biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; ISS:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0045627; P:positive regulation of T-helper 1 cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0060491; P:regulation of cell projection assembly; ISS:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0071731; P:response to nitric oxide; IDA:BHF-UCL.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0034695; P:response to prostaglandin E; IDA:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; ISS:BHF-UCL.
//
ID   CCL20_HUMAN             Reviewed;          96 AA.
AC   P78556; Q53S51; Q99664;
DE   RecName: Full=C-C motif chemokine 20;
DE   AltName: Full=Beta-chemokine exodus-1;
DE   AltName: Full=CC chemokine LARC;
DE   AltName: Full=Liver and activation-regulated chemokine;
DE   AltName: Full=Macrophage inflammatory protein 3 alpha;
DE            Short=MIP-3-alpha;
DE   AltName: Full=Small-inducible cytokine A20;
DE   Contains:
DE     RecName: Full=CCL20(1-67);
DE   Contains:
DE     RecName: Full=CCL20(1-64);
DE   Contains:
DE     RecName: Full=CCL20(2-70);
DE   Flags: Precursor;
GN   Name=CCL20; Synonyms=LARC, MIP3A, SCYA20;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0042466; P:chemokinesis; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL21_HUMAN             Reviewed;         134 AA.
AC   O00585;
DE   RecName: Full=C-C motif chemokine 21;
DE   AltName: Full=6Ckine;
DE   AltName: Full=Beta-chemokine exodus-2;
DE   AltName: Full=Secondary lymphoid-tissue chemokine;
DE            Short=SLC;
DE   AltName: Full=Small-inducible cytokine A21;
DE   Flags: Precursor;
GN   Name=CCL21; Synonyms=SCYA21; ORFNames=UNQ784/PRO1600;
DR   GO; GO:0031732; F:CCR7 chemokine receptor binding; ISS:BHF-UCL.
DR   GO; GO:0008009; F:chemokine activity; IDA:BHF-UCL.
DR   GO; GO:0042379; F:chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0048469; P:cell maturation; ISS:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0097026; P:dendritic cell dendrite assembly; ISS:BHF-UCL.
DR   GO; GO:0001768; P:establishment of T cell polarity; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0001771; P:immunological synapse formation; ISS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; NAS:BHF-UCL.
DR   GO; GO:0035759; P:mesangial cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:2000548; P:negative regulation of dendritic cell dendrite assembly; ISS:BHF-UCL.
DR   GO; GO:2000107; P:negative regulation of leukocyte apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:BHF-UCL.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:2000147; P:positive regulation of cell motility; IDA:BHF-UCL.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.
DR   GO; GO:0010560; P:positive regulation of glycoprotein biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.
DR   GO; GO:2000529; P:positive regulation of myeloid dendritic cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IDA:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; ISS:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0034695; P:response to prostaglandin E; IDA:BHF-UCL.
DR   GO; GO:0031529; P:ruffle organization; IDA:BHF-UCL.
DR   GO; GO:0031295; P:T cell costimulation; ISS:BHF-UCL.
//
ID   CCL22_HUMAN             Reviewed;          93 AA.
AC   O00626; A0N0Q6; B2R4W2;
DE   RecName: Full=C-C motif chemokine 22;
DE   AltName: Full=CC chemokine STCP-1;
DE   AltName: Full=MDC(1-69);
DE   AltName: Full=Macrophage-derived chemokine;
DE   AltName: Full=Small-inducible cytokine A22;
DE   AltName: Full=Stimulated T-cell chemotactic protein 1;
DE   Contains:
DE     RecName: Full=MDC(3-69);
DE   Contains:
DE     RecName: Full=MDC(5-69);
DE   Contains:
DE     RecName: Full=MDC(7-69);
DE   Flags: Precursor;
GN   Name=CCL22; Synonyms=MDC, SCYA22; ORFNames=A-152E5.1;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL23_HUMAN             Reviewed;         120 AA.
AC   P55773; B7ZKQ3; O00174; O75950; Q52LD4;
DE   RecName: Full=C-C motif chemokine 23;
DE   AltName: Full=CK-beta-8;
DE            Short=CKB-8;
DE   AltName: Full=Macrophage inflammatory protein 3;
DE            Short=MIP-3;
DE   AltName: Full=Myeloid progenitor inhibitory factor 1;
DE            Short=MPIF-1;
DE   AltName: Full=Small-inducible cytokine A23;
DE   Contains:
DE     RecName: Full=CCL23(19-99);
DE   Contains:
DE     RecName: Full=CCL23(22-99);
DE   Contains:
DE     RecName: Full=CCL23(27-99);
DE   Contains:
DE     RecName: Full=CCL23(30-99);
DE   Flags: Precursor;
GN   Name=CCL23; Synonyms=MIP3, MPIF1, SCYA23;
DR   GO; GO:0031726; F:CCR1 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0002548; P:monocyte chemotaxis; IC:UniProtKB.
DR   GO; GO:2001264; P:negative regulation of C-C chemokine binding; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CCL24_HUMAN             Reviewed;         119 AA.
AC   O00175; B2R5K2;
DE   RecName: Full=C-C motif chemokine 24;
DE   AltName: Full=CK-beta-6;
DE   AltName: Full=Eosinophil chemotactic protein 2;
DE   AltName: Full=Eotaxin-2;
DE   AltName: Full=Myeloid progenitor inhibitory factor 2;
DE            Short=MPIF-2;
DE   AltName: Full=Small-inducible cytokine A24;
DE   Flags: Precursor;
GN   Name=CCL24; Synonyms=MPIF2, SCYA24;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000418; P:positive regulation of eosinophil migration; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL25_HUMAN             Reviewed;         150 AA.
AC   O15444; A1L4J4; A6NI52; A8K9E7; B5MCA5; Q96KJ7;
DE   RecName: Full=C-C motif chemokine 25;
DE   AltName: Full=Chemokine TECK;
DE   AltName: Full=Small-inducible cytokine A25;
DE   AltName: Full=Thymus-expressed chemokine;
DE   Flags: Precursor;
GN   Name=CCL25; Synonyms=SCYA25, TECK;
DR   GO; GO:0031735; F:CCR10 chemokine receptor binding; IDA:BHF-UCL.
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0042379; F:chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
//
ID   CCL26_HUMAN             Reviewed;          94 AA.
AC   Q9Y258; A0N0Q5; Q52LV8;
DE   RecName: Full=C-C motif chemokine 26;
DE   AltName: Full=CC chemokine IMAC;
DE   AltName: Full=Eotaxin-3;
DE   AltName: Full=Macrophage inflammatory protein 4-alpha;
DE            Short=MIP-4-alpha;
DE   AltName: Full=Small-inducible cytokine A26;
DE   AltName: Full=Thymic stroma chemokine-1;
DE            Short=TSC-1;
DE   Flags: Precursor;
GN   Name=CCL26; Synonyms=SCYA26; ORFNames=UNQ216/PRO242;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CCL27_HUMAN             Reviewed;         112 AA.
AC   Q9Y4X3;
DE   RecName: Full=C-C motif chemokine 27;
DE   AltName: Full=CC chemokine ILC;
DE   AltName: Full=Cutaneous T-cell-attracting chemokine;
DE            Short=CTACK;
DE   AltName: Full=ESkine;
DE   AltName: Full=IL-11 R-alpha-locus chemokine;
DE   AltName: Full=Skinkine;
DE   AltName: Full=Small-inducible cytokine A27;
DE   Flags: Precursor;
GN   Name=CCL27; Synonyms=ILC, SCYA27;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   CCL28_HUMAN             Reviewed;         127 AA.
AC   Q9NRJ3; D7RIE7;
DE   RecName: Full=C-C motif chemokine 28;
DE   AltName: Full=Mucosae-associated epithelial chemokine;
DE            Short=MEC;
DE   AltName: Full=Protein CCK1;
DE   AltName: Full=Small-inducible cytokine A28;
DE   Flags: Precursor;
GN   Name=CCL28; Synonyms=SCYA28;
DR   GO; GO:0008009; F:chemokine activity; TAS:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   CCL2_HUMAN              Reviewed;          99 AA.
AC   P13500; B2R4V3; Q9UDF3;
DE   RecName: Full=C-C motif chemokine 2;
DE   AltName: Full=HC11;
DE   AltName: Full=Monocyte chemoattractant protein 1;
DE   AltName: Full=Monocyte chemotactic and activating factor;
DE            Short=MCAF;
DE   AltName: Full=Monocyte chemotactic protein 1;
DE            Short=MCP-1;
DE   AltName: Full=Monocyte secretory protein JE;
DE   AltName: Full=Small-inducible cytokine A2;
DE   Flags: Precursor;
GN   Name=CCL2; Synonyms=MCP1, SCYA2;
DR   GO; GO:0031727; F:CCR2 chemokine receptor binding; ISS:BHF-UCL.
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0043615; P:astrocyte cell migration; IDA:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0019725; P:cellular homeostasis; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0035684; P:helper T cell extravasation; ISS:BHF-UCL.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; IEA:Ensembl.
DR   GO; GO:0048246; P:macrophage chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0034351; P:negative regulation of glial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000502; P:negative regulation of natural killer cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:2000427; P:positive regulation of apoptotic cell clearance; ISS:BHF-UCL.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0090265; P:positive regulation of immune complex clearance by monocytes and macrophages; IEA:Ensembl.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0050870; P:positive regulation of T cell activation; ISS:BHF-UCL.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0010574; P:regulation of vascular endothelial growth factor production; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0009617; P:response to bacterium; IEP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0033552; P:response to vitamin B3; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
//
ID   CCL3_HUMAN              Reviewed;          92 AA.
AC   P10147;
DE   RecName: Full=C-C motif chemokine 3;
DE   AltName: Full=G0/G1 switch regulatory protein 19-1;
DE   AltName: Full=Macrophage inflammatory protein 1-alpha;
DE            Short=MIP-1-alpha;
DE   AltName: Full=PAT 464.1;
DE   AltName: Full=SIS-beta;
DE   AltName: Full=Small-inducible cytokine A3;
DE   AltName: Full=Tonsillar lymphocyte LD78 alpha protein;
DE   Contains:
DE     RecName: Full=MIP-1-alpha(4-69);
DE     AltName: Full=LD78-alpha(4-69);
DE   Flags: Precursor;
GN   Name=CCL3; Synonyms=G0S19-1, MIP1A, SCYA3;
DR   GO; GO:0004698; F:calcium-dependent protein kinase C activity; IDA:UniProtKB.
DR   GO; GO:0031726; F:CCR1 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0031730; F:CCR5 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0016301; F:kinase activity; IDA:UniProtKB.
DR   GO; GO:0016004; F:phospholipase activator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0043615; P:astrocyte cell migration; ISS:UniProtKB.
DR   GO; GO:0007610; P:behavior; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0001775; P:cell activation; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043308; P:eosinophil degranulation; IDA:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0071621; P:granulocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048246; P:macrophage chemotaxis; ISS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; TAS:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:UniProtKB.
DR   GO; GO:2000503; P:positive regulation of natural killer cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEP:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IDA:UniProtKB.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:UniProtKB.
DR   GO; GO:0070723; P:response to cholesterol; IDA:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0023052; P:signaling; IEP:UniProtKB.
DR   GO; GO:0010818; P:T cell chemotaxis; IDA:UniProtKB.
//
ID   CCL4_HUMAN              Reviewed;          92 AA.
AC   P13236; P22617; Q13704; Q3SXL8; Q6FGI8;
DE   RecName: Full=C-C motif chemokine 4;
DE   AltName: Full=G-26 T-lymphocyte-secreted protein;
DE   AltName: Full=HC21;
DE   AltName: Full=Lymphocyte activation gene 1 protein;
DE            Short=LAG-1;
DE   AltName: Full=MIP-1-beta(1-69);
DE   AltName: Full=Macrophage inflammatory protein 1-beta;
DE            Short=MIP-1-beta;
DE   AltName: Full=PAT 744;
DE   AltName: Full=Protein H400;
DE   AltName: Full=SIS-gamma;
DE   AltName: Full=Small-inducible cytokine A4;
DE   AltName: Full=T-cell activation protein 2;
DE            Short=ACT-2;
DE   Contains:
DE     RecName: Full=MIP-1-beta(3-69);
DE   Flags: Precursor;
GN   Name=CCL4; Synonyms=LAG1, MIP1B, SCYA4;
DR   GO; GO:0031726; F:CCR1 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0031730; F:CCR5 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:UniProtKB.
DR   GO; GO:2000503; P:positive regulation of natural killer cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL5_HUMAN              Reviewed;          91 AA.
AC   P13501; O43646; Q0QVW8; Q4ZGJ1; Q9NYA2; Q9UBG2; Q9UC99;
DE   RecName: Full=C-C motif chemokine 5;
DE   AltName: Full=EoCP;
DE   AltName: Full=Eosinophil chemotactic cytokine;
DE   AltName: Full=SIS-delta;
DE   AltName: Full=Small-inducible cytokine A5;
DE   AltName: Full=T cell-specific protein P228;
DE            Short=TCP228;
DE   AltName: Full=T-cell-specific protein RANTES;
DE   Contains:
DE     RecName: Full=RANTES(3-68);
DE   Contains:
DE     RecName: Full=RANTES(4-68);
DE   Flags: Precursor;
GN   Name=CCL5; Synonyms=D17S136E, SCYA5;
DR   GO; GO:0031726; F:CCR1 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0031729; F:CCR4 chemokine receptor binding; TAS:BHF-UCL.
DR   GO; GO:0031730; F:CCR5 chemokine receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; NAS:UniProtKB.
DR   GO; GO:0046817; F:chemokine receptor antagonist activity; IDA:BHF-UCL.
DR   GO; GO:0042379; F:chemokine receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0016004; F:phospholipase activator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:BHF-UCL.
DR   GO; GO:0030298; F:receptor signaling protein tyrosine kinase activator activity; IDA:BHF-UCL.
DR   GO; GO:0031584; P:activation of phospholipase D activity; IDA:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; NAS:UniProtKB.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048246; P:macrophage chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0002548; P:monocyte chemotaxis; IC:UniProtKB.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0070100; P:negative regulation of chemokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000110; P:negative regulation of macrophage apoptotic process; IEA:Ensembl.
DR   GO; GO:0070233; P:negative regulation of T cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0042119; P:neutrophil activation; IDA:BHF-UCL.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0010535; P:positive regulation of activation of JAK2 kinase activity; TAS:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0033634; P:positive regulation of cell-cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:0031328; P:positive regulation of cellular biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0034112; P:positive regulation of homotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0045089; P:positive regulation of innate immune response; TAS:BHF-UCL.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; TAS:BHF-UCL.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:2000503; P:positive regulation of natural killer cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0070234; P:positive regulation of T cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045948; P:positive regulation of translational initiation; NAS:BHF-UCL.
DR   GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IDA:BHF-UCL.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; TAS:BHF-UCL.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0051262; P:protein tetramerization; IDA:BHF-UCL.
DR   GO; GO:0002676; P:regulation of chronic inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0050863; P:regulation of T cell activation; IDA:BHF-UCL.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:BHF-UCL.
//
ID   CCL7_HUMAN              Reviewed;          99 AA.
AC   P80098; Q569J6;
DE   RecName: Full=C-C motif chemokine 7;
DE   AltName: Full=Monocyte chemoattractant protein 3;
DE   AltName: Full=Monocyte chemotactic protein 3;
DE            Short=MCP-3;
DE   AltName: Full=NC28;
DE   AltName: Full=Small-inducible cytokine A7;
DE   Flags: Precursor;
GN   Name=CCL7; Synonyms=MCP3, SCYA6, SCYA7;
DR   GO; GO:0031726; F:CCR1 chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0002548; P:monocyte chemotaxis; IC:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:2000503; P:positive regulation of natural killer cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCL8_HUMAN              Reviewed;          99 AA.
AC   P80075; A0AV77; P78388;
DE   RecName: Full=C-C motif chemokine 8;
DE   AltName: Full=HC14;
DE   AltName: Full=Monocyte chemoattractant protein 2;
DE   AltName: Full=Monocyte chemotactic protein 2;
DE            Short=MCP-2;
DE   AltName: Full=Small-inducible cytokine A8;
DE   Contains:
DE     RecName: Full=MCP-2(6-76);
DE   Flags: Precursor;
GN   Name=CCL8; Synonyms=MCP2, SCYA10, SCYA8;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0016004; F:phospholipase activator activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCM2L_HUMAN             Reviewed;         571 AA.
AC   Q9NUG4; Q5JYR9; Q8N5F1; Q8N6G8; Q96MD5;
DE   RecName: Full=Cerebral cavernous malformations 2 protein-like;
DE            Short=CCM2-like;
GN   Name=CCM2L; Synonyms=C20orf160;
//
ID   CCM2_HUMAN              Reviewed;         444 AA.
AC   Q9BSQ5; A4D2L4; B3KUV0; D3DVL4; E9PDJ3; F5H0E1; F5H551; Q71RE5;
AC   Q8TAT4;
DE   RecName: Full=Malcavernin;
DE   AltName: Full=Cerebral cavernous malformations 2 protein;
GN   Name=CCM2; Synonyms=C7orf22; ORFNames=PP10187;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060837; P:blood vessel endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; IEA:Ensembl.
DR   GO; GO:0001885; P:endothelial cell development; IEA:Ensembl.
DR   GO; GO:0061154; P:endothelial tube morphogenesis; IMP:MGI.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; IMP:UniProtKB.
DR   GO; GO:0048845; P:venous blood vessel morphogenesis; IEA:Ensembl.
//
ID   CCNA1_HUMAN             Reviewed;         465 AA.
AC   P78396; B7Z7E3; Q5T3V0; Q5U0G2; Q8IY91;
DE   RecName: Full=Cyclin-A1;
GN   Name=CCNA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007141; P:male meiosis I; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   CCNA2_HUMAN             Reviewed;         432 AA.
AC   P20248; A8K7B6; Q2M3U6; Q4W5P4; Q6LER8;
DE   RecName: Full=Cyclin-A2;
DE            Short=Cyclin-A;
GN   Name=CCNA2; Synonyms=CCN1, CCNA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; TAS:ProtInc.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
//
ID   CCNB1_HUMAN             Reviewed;         433 AA.
AC   P14635; A8K066; Q5TZP9;
DE   RecName: Full=G2/mitotic-specific cyclin-B1;
GN   Name=CCNB1; Synonyms=CCNB;
DR   GO; GO:0016301; F:kinase activity; IEA:Ensembl.
DR   GO; GO:0005113; F:patched binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071283; P:cellular response to iron(III) ion; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:BHF-UCL.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0071174; P:mitotic spindle checkpoint; IMP:BHF-UCL.
DR   GO; GO:0043148; P:mitotic spindle stabilization; IMP:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0051987; P:positive regulation of attachment of spindle microtubules to kinetochore; IMP:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0033129; P:positive regulation of histone phosphorylation; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0031442; P:positive regulation of mRNA 3'-end processing; IEA:Ensembl.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0060623; P:regulation of chromosome condensation; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046680; P:response to DDT; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
//
ID   CCNB2_HUMAN             Reviewed;         398 AA.
AC   O95067; B3KM93; Q6FI99;
DE   RecName: Full=G2/mitotic-specific cyclin-B2;
GN   Name=CCNB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0040007; P:growth; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   CCNB3_HUMAN             Reviewed;        1395 AA.
AC   Q8WWL7; B1AQI5; B1AQI6; Q96SB5; Q96SB6; Q96SB7; Q9NT38;
DE   RecName: Full=G2/mitotic-specific cyclin-B3;
GN   Name=CCNB3; Synonyms=CYCB3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:InterPro.
//
ID   CCNC_HUMAN              Reviewed;         283 AA.
AC   P24863; B4DPZ1; Q9H543;
DE   RecName: Full=Cyclin-C;
DE   AltName: Full=SRB11 homolog;
DE            Short=hSRB11;
GN   Name=CCNC;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   CCND2_HUMAN             Reviewed;         289 AA.
AC   P30279; A8K531; Q13955; Q5U035;
DE   RecName: Full=G1/S-specific cyclin-D2;
GN   Name=CCND2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
//
ID   CCND3_HUMAN             Reviewed;         292 AA.
AC   P30281; B2RD63; B3KQ22; E9PAS4; E9PB36; Q5T8J0; Q6FG62; Q96F49;
DE   RecName: Full=G1/S-specific cyclin-D3;
GN   Name=CCND3;
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
//
ID   CCND1_HUMAN             Reviewed;         295 AA.
AC   P24385; Q6LEF0;
DE   RecName: Full=G1/S-specific cyclin-D1;
DE   AltName: Full=B-cell lymphoma 1 protein;
DE            Short=BCL-1;
DE   AltName: Full=BCL-1 oncogene;
DE   AltName: Full=PRAD1 oncogene;
GN   Name=CCND1; Synonyms=BCL1, PRAD1;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0070064; F:proline-rich region binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0000320; P:re-entry into mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEP:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0070141; P:response to UV-A; IDA:BHF-UCL.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CCNE1_HUMAN             Reviewed;         410 AA.
AC   P24864; A8K684; Q14091; Q8NFG1; Q92501; Q9UD21;
DE   RecName: Full=G1/S-specific cyclin-E1;
GN   Name=CCNE1; Synonyms=CCNE;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0016301; F:kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IMP:MGI.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   CCNE2_HUMAN             Reviewed;         404 AA.
AC   O96020; O95439;
DE   RecName: Full=G1/S-specific cyclin-E2;
GN   Name=CCNE2;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
//
ID   CCNF_HUMAN              Reviewed;         786 AA.
AC   P41002; B2R8H3; Q96EG9;
DE   RecName: Full=Cyclin-F;
DE   AltName: Full=F-box only protein 1;
GN   Name=CCNF; Synonyms=FBX1, FBXO1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0010826; P:negative regulation of centrosome duplication; IDA:UniProtKB.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000320; P:re-entry into mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   CCNG1_HUMAN             Reviewed;         295 AA.
AC   P51959; B2R7B2; D3DQK7; Q15757; Q96L32;
DE   RecName: Full=Cyclin-G1;
DE            Short=Cyclin-G;
GN   Name=CCNG1; Synonyms=CCNG, CYCG1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0006949; P:syncytium formation; IEA:Ensembl.
//
ID   CCNG2_HUMAN             Reviewed;         344 AA.
AC   Q16589; B4DF25; Q6FGA7; Q6FGC6;
DE   RecName: Full=Cyclin-G2;
GN   Name=CCNG2;
DR   GO; GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
//
ID   CCNH_HUMAN              Reviewed;         323 AA.
AC   P51946; Q53X72; Q8TBL9;
DE   RecName: Full=Cyclin-H;
DE   AltName: Full=MO15-associated protein;
DE   AltName: Full=p34;
DE   AltName: Full=p37;
GN   Name=CCNH;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CCNI2_HUMAN             Reviewed;         369 AA.
AC   Q6ZMN8; B2RNE2;
DE   RecName: Full=Cyclin-I2;
GN   Name=CCNI2;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
//
ID   CCNI_HUMAN              Reviewed;         377 AA.
AC   Q14094; B2R6M0;
DE   RecName: Full=Cyclin-I;
GN   Name=CCNI;
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   CCNJL_HUMAN             Reviewed;         435 AA.
AC   Q8IV13; Q6ZN43; Q9H7W8;
DE   RecName: Full=Cyclin-J-like protein;
GN   Name=CCNJL;
//
ID   CCNJ_HUMAN              Reviewed;         372 AA.
AC   Q5T5M9; B7Z4E7; Q86XL1; Q9NV69;
DE   RecName: Full=Cyclin-J;
GN   Name=CCNJ;
//
ID   CCNK_HUMAN              Reviewed;         580 AA.
AC   O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9;
DE   RecName: Full=Cyclin-K;
GN   Name=CCNK; Synonyms=CPR4;
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:MGI.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:MGI.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:MGI.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IGI:MGI.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CCNL1_HUMAN             Reviewed;         526 AA.
AC   Q9UK58; B3KMY3; Q6NVY9; Q6UWS7; Q8NI48; Q96QT0; Q9NZF3;
DE   RecName: Full=Cyclin-L1;
DE            Short=Cyclin-L;
GN   Name=CCNL1; ORFNames=BM-001, UNQ530/PRO1073;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CCNL2_HUMAN             Reviewed;         520 AA.
AC   Q96S94; A8K8A3; B1B152; Q5T2N5; Q5T2N6; Q6IQ12; Q7Z4Z8; Q8N3C9;
AC   Q8N3D5; Q8NHE3; Q8TEL0; Q96B00;
DE   RecName: Full=Cyclin-L2;
DE   AltName: Full=Paneth cell-enhanced expression protein;
GN   Name=CCNL2; ORFNames=SB138;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CCNO_HUMAN              Reviewed;         350 AA.
AC   P22674; A8K1W5; Q0P6J2; Q9H6B0; Q9UMD5;
DE   RecName: Full=Cyclin-O;
GN   Name=CCNO;
DR   GO; GO:0004844; F:uracil DNA N-glycosylase activity; IDA:HGNC.
DR   GO; GO:0006284; P:base-excision repair; IDA:HGNC.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IDA:UniProtKB.
DR   GO; GO:0051301; P:cell division; IDA:UniProtKB.
DR   GO; GO:0045008; P:depyrimidination; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   CCNT1_HUMAN             Reviewed;         726 AA.
AC   O60563; A9XU13; E7EX76; O60581;
DE   RecName: Full=Cyclin-T1;
DE            Short=CycT1;
DE            Short=Cyclin-T;
GN   Name=CCNT1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017069; F:snRNA binding; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IPI:MGI.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CCNT2_HUMAN             Reviewed;         730 AA.
AC   O60583; A8KA48; D3DP73; D3DP74; O60582; Q29R66; Q53SR4; Q5I1Y0;
DE   RecName: Full=Cyclin-T2;
DE            Short=CycT2;
GN   Name=CCNT2;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CCNY_HUMAN              Reviewed;         341 AA.
AC   Q8ND76; B7ZKX9; D3DRY9; Q2M3V4; Q2TU96; Q6NT86; Q7Z4U7; Q8TEX2;
AC   Q8TEX3; Q96M99; Q96P45;
DE   RecName: Full=Cyclin-Y;
DE            Short=Cyc-Y;
DE   AltName: Full=Cyclin box protein 1;
DE   AltName: Full=Cyclin fold protein 1;
DE   AltName: Full=cyclin-X;
GN   Name=CCNY; Synonyms=C10orf9, CBCP1, CFP1;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CCPG1_HUMAN             Reviewed;         757 AA.
AC   Q9ULG6; A0PJH3; A8K9T0; O14712; Q05DG4; Q5U5S7; Q8IYV8; Q9BY53;
AC   Q9HA17;
DE   RecName: Full=Cell cycle progression protein 1;
DE   AltName: Full=Cell cycle progression restoration protein 8;
GN   Name=CCPG1; Synonyms=CCP8, CPR8, KIAA1254;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IMP:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProt.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2001106; P:regulation of Rho guanyl-nucleotide exchange factor activity; IEA:Ensembl.
//
ID   CCR10_HUMAN             Reviewed;         362 AA.
AC   P46092; Q4V749; Q6T7X2; Q9NZG2;
DE   RecName: Full=C-C chemokine receptor type 10;
DE            Short=C-C CKR-10;
DE            Short=CC-CKR-10;
DE            Short=CCR-10;
DE   AltName: Full=G-protein coupled receptor 2;
GN   Name=CCR10; Synonyms=GPR2;
DR   GuidetoPHARMACOLOGY; 67; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
//
ID   CCR1_HUMAN              Reviewed;         355 AA.
AC   P32246; Q86VA9;
DE   RecName: Full=C-C chemokine receptor type 1;
DE            Short=C-C CKR-1;
DE            Short=CC-CKR-1;
DE            Short=CCR-1;
DE            Short=CCR1;
DE   AltName: Full=HM145;
DE   AltName: Full=LD78 receptor;
DE   AltName: Full=Macrophage inflammatory protein 1-alpha receptor;
DE            Short=MIP-1alpha-R;
DE   AltName: Full=RANTES-R;
DE   AltName: CD_antigen=CD191;
GN   Name=CCR1; Synonyms=CMKBR1, CMKR1, SCYAR1;
DR   GuidetoPHARMACOLOGY; 58; -.
DR   GO; GO:0019957; F:C-C chemokine binding; IPI:UniProtKB.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IDA:UniProtKB.
DR   GO; GO:0071791; F:chemokine (C-C motif) ligand 5 binding; IPI:UniProtKB.
DR   GO; GO:0035717; F:chemokine (C-C motif) ligand 7 binding; IPI:UniProtKB.
DR   GO; GO:0004950; F:chemokine receptor activity; IDA:UniProtKB.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IMP:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IMP:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
//
ID   CCR2_HUMAN              Reviewed;         374 AA.
AC   P41597; A0AVQ3; B2RMT0; Q4VBL2;
DE   RecName: Full=C-C chemokine receptor type 2;
DE            Short=C-C CKR-2;
DE            Short=CC-CKR-2;
DE            Short=CCR-2;
DE            Short=CCR2;
DE   AltName: Full=Monocyte chemoattractant protein 1 receptor;
DE            Short=MCP-1-R;
DE   AltName: CD_antigen=CD192;
GN   Name=CCR2; Synonyms=CMKBR2;
DR   GuidetoPHARMACOLOGY; 59; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:InterPro.
DR   GO; GO:0031727; F:CCR2 chemokine receptor binding; IDA:MGI.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0019725; P:cellular homeostasis; ISS:BHF-UCL.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:MGI.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0043310; P:negative regulation of eosinophil degranulation; ISS:BHF-UCL.
DR   GO; GO:0002829; P:negative regulation of type 2 immune response; ISS:BHF-UCL.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000464; P:positive regulation of astrocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:2000451; P:positive regulation of CD8-positive, alpha-beta T cell extravasation; ISS:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:2000473; P:positive regulation of hematopoietic stem cell migration; ISS:BHF-UCL.
DR   GO; GO:0090265; P:positive regulation of immune complex clearance by monocytes and macrophages; ISS:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; ISS:BHF-UCL.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:2000439; P:positive regulation of monocyte extravasation; ISS:BHF-UCL.
DR   GO; GO:0050870; P:positive regulation of T cell activation; ISS:BHF-UCL.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; ISS:BHF-UCL.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0010574; P:regulation of vascular endothelial growth factor production; ISS:BHF-UCL.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0035705; P:T-helper 17 cell chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CCR3_HUMAN              Reviewed;         355 AA.
AC   P51677; B3KVQ1; F5GWL6; Q15748; Q2YDB9; Q86WD2; Q8TDP6; Q9ULY8;
DE   RecName: Full=C-C chemokine receptor type 3;
DE            Short=C-C CKR-3;
DE            Short=CC-CKR-3;
DE            Short=CCR-3;
DE            Short=CCR3;
DE            Short=CKR3;
DE   AltName: Full=Eosinophil eotaxin receptor;
DE   AltName: CD_antigen=CD193;
GN   Name=CCR3; Synonyms=CMKBR3;
DR   GuidetoPHARMACOLOGY; 60; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CCR4_HUMAN              Reviewed;         360 AA.
AC   P51679; Q9ULY6; Q9ULY7;
DE   RecName: Full=C-C chemokine receptor type 4;
DE            Short=C-C CKR-4;
DE            Short=CC-CKR-4;
DE            Short=CCR-4;
DE            Short=CCR4;
DE   AltName: Full=K5-5;
DE   AltName: CD_antigen=CD194;
GN   Name=CCR4; Synonyms=CMKBR4;
DR   GuidetoPHARMACOLOGY; 61; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0002507; P:tolerance induction; IEA:Ensembl.
//
ID   CCR5_HUMAN              Reviewed;         352 AA.
AC   P51681; O14692; O14693; O14695; O14696; O14697; O14698; O14699;
AC   O14700; O14701; O14702; O14703; O14704; O14705; O14706; O14707;
AC   O14708; O15538; Q9UPA4;
DE   RecName: Full=C-C chemokine receptor type 5;
DE            Short=C-C CKR-5;
DE            Short=CC-CKR-5;
DE            Short=CCR-5;
DE            Short=CCR5;
DE   AltName: Full=CHEMR13;
DE   AltName: Full=HIV-1 fusion coreceptor;
DE   AltName: CD_antigen=CD195;
GN   Name=CCR5; Synonyms=CMKBR5;
DR   GuidetoPHARMACOLOGY; 62; -.
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0019957; F:C-C chemokine binding; IPI:UniProtKB.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; NAS:UniProtKB.
DR   GO; GO:0071791; F:chemokine (C-C motif) ligand 5 binding; IPI:UniProtKB.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:InterPro.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0030260; P:entry into host cell; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0000165; P:MAPK cascade; IEP:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IEA:InterPro.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:UniProtKB.
DR   GO; GO:0070723; P:response to cholesterol; IMP:UniProtKB.
DR   GO; GO:0023052; P:signaling; IEP:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CCR6_HUMAN              Reviewed;         374 AA.
AC   P51684; E1P5C6; P78553; Q92846;
DE   RecName: Full=C-C chemokine receptor type 6;
DE            Short=C-C CKR-6;
DE            Short=CC-CKR-6;
DE            Short=CCR-6;
DE   AltName: Full=Chemokine receptor-like 3;
DE            Short=CKR-L3;
DE   AltName: Full=DRY6;
DE   AltName: Full=G-protein coupled receptor 29;
DE   AltName: Full=GPR-CY4;
DE            Short=GPRCY4;
DE   AltName: Full=LARC receptor;
DE   AltName: CD_antigen=CD196;
GN   Name=CCR6; Synonyms=CKRL3, CMKBR6, GPR29, STRL22;
DR   GuidetoPHARMACOLOGY; 63; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:InterPro.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CCR7_HUMAN              Reviewed;         378 AA.
AC   P32248;
DE   RecName: Full=C-C chemokine receptor type 7;
DE            Short=C-C CKR-7;
DE            Short=CC-CKR-7;
DE            Short=CCR-7;
DE   AltName: Full=BLR2;
DE   AltName: Full=CDw197;
DE   AltName: Full=Epstein-Barr virus-induced G-protein coupled receptor 1;
DE            Short=EBI1;
DE            Short=EBV-induced G-protein coupled receptor 1;
DE   AltName: Full=MIP-3 beta receptor;
DE   AltName: CD_antigen=CD197;
DE   Flags: Precursor;
GN   Name=CCR7; Synonyms=CMKBR7, EBI1, EVI1;
DR   GuidetoPHARMACOLOGY; 64; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; ISS:BHF-UCL.
DR   GO; GO:0038117; F:C-C motif chemokine 19 receptor activity; IDA:UniProtKB.
DR   GO; GO:0038121; F:C-C motif chemokine 21 receptor activity; IDA:UniProtKB.
DR   GO; GO:0035757; F:chemokine (C-C motif) ligand 19 binding; IPI:BHF-UCL.
DR   GO; GO:0035758; F:chemokine (C-C motif) ligand 21 binding; IPI:BHF-UCL.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:BHF-UCL.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IC:BHF-UCL.
DR   GO; GO:0038115; P:chemokine (C-C motif) ligand 19 signaling pathway; IDA:GOC.
DR   GO; GO:0038116; P:chemokine (C-C motif) ligand 21 signaling pathway; IDA:GOC.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; ISS:GOC.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; IC:BHF-UCL.
DR   GO; GO:0001768; P:establishment of T cell polarity; IC:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; NAS:BHF-UCL.
DR   GO; GO:0072610; P:interleukin-12 secretion; ISS:BHF-UCL.
DR   GO; GO:0097022; P:lymphocyte migration into lymph node; TAS:BHF-UCL.
DR   GO; GO:0097029; P:mature dendritic cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0002408; P:myeloid dendritic cell chemotaxis; IC:BHF-UCL.
DR   GO; GO:2000107; P:negative regulation of leukocyte apoptotic process; IC:BHF-UCL.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IC:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IC:BHF-UCL.
DR   GO; GO:2000147; P:positive regulation of cell motility; IC:BHF-UCL.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IC:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.
DR   GO; GO:2000510; P:positive regulation of dendritic cell chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IC:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IC:BHF-UCL.
DR   GO; GO:2000526; P:positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation; ISS:BHF-UCL.
DR   GO; GO:0002922; P:positive regulation of humoral immune response; ISS:BHF-UCL.
DR   GO; GO:0002885; P:positive regulation of hypersensitivity; ISS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IC:BHF-UCL.
DR   GO; GO:2000522; P:positive regulation of immunological synapse formation; ISS:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IC:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IC:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IC:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IC:BHF-UCL.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IC:BHF-UCL.
DR   GO; GO:2000525; P:positive regulation of T cell costimulation; ISS:BHF-UCL.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:2000547; P:regulation of dendritic cell dendrite assembly; ISS:BHF-UCL.
DR   GO; GO:0032649; P:regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0050706; P:regulation of interleukin-1 beta secretion; ISS:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IC:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071731; P:response to nitric oxide; IC:BHF-UCL.
DR   GO; GO:0034695; P:response to prostaglandin E; IC:BHF-UCL.
DR   GO; GO:0031529; P:ruffle organization; IC:BHF-UCL.
//
ID   CCR8_HUMAN              Reviewed;         355 AA.
AC   P51685; B2RC64; Q3KNQ8; Q9BYX5;
DE   RecName: Full=C-C chemokine receptor type 8;
DE            Short=C-C CKR-8;
DE            Short=CC-CKR-8;
DE            Short=CCR-8;
DE   AltName: Full=CC chemokine receptor CHEMR1;
DE   AltName: Full=CMKBRL2;
DE   AltName: Full=Chemokine receptor-like 1;
DE            Short=CKR-L1;
DE   AltName: Full=GPR-CY6;
DE            Short=GPRCY6;
DE   AltName: Full=TER1;
DE   AltName: CD_antigen=CDw198;
GN   Name=CCR8; Synonyms=CKRL1, CMKBR8, CMKBRL2;
DR   GuidetoPHARMACOLOGY; 65; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
//
ID   CCR9_HUMAN              Reviewed;         369 AA.
AC   P51686; Q4VBM3; Q549E0; Q9UQQ6;
DE   RecName: Full=C-C chemokine receptor type 9;
DE            Short=C-C CKR-9;
DE            Short=CC-CKR-9;
DE            Short=CCR-9;
DE   AltName: Full=G-protein coupled receptor 28;
DE   AltName: Full=GPR-9-6;
DE   AltName: CD_antigen=CDw199;
GN   Name=CCR9; Synonyms=GPR28;
DR   GuidetoPHARMACOLOGY; 66; -.
DR   GO; GO:0016493; F:C-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
//
ID   CCRL2_HUMAN             Reviewed;         344 AA.
AC   O00421; B4DKQ8; O75307; Q4VBB0; Q6IPX0; Q7KYQ9; Q96KP5; Q9UPG0;
DE   RecName: Full=C-C chemokine receptor-like 2;
DE   AltName: Full=Chemokine receptor CCR11;
DE   AltName: Full=Chemokine receptor X;
DE   AltName: Full=Putative MCP-1 chemokine receptor;
GN   Name=CCRL2; Synonyms=CCR11, CCR6, CKRX, CRAM, HCR;
DR   GuidetoPHARMACOLOGY; 78; -.
DR   GO; GO:0048020; F:CCR chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0042379; F:chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
//
ID   CCSAP_HUMAN             Reviewed;         270 AA.
AC   Q6IQ19; A8K5X2; Q6P9G2; Q6ZW85; Q8IXU1; Q96BM2;
DE   RecName: Full=Centriole, cilia and spindle-associated protein;
GN   Name=CCSAP; Synonyms=C1orf96, CSAP;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0060296; P:regulation of cilium beat frequency involved in ciliary motility; ISS:UniProtKB.
DR   GO; GO:0045995; P:regulation of embryonic development; ISS:UniProtKB.
//
ID   CCSE1_HUMAN             Reviewed;         900 AA.
AC   Q9C0I3; Q4W5M0; Q86V57;
DE   RecName: Full=Serine-rich coiled-coil domain-containing protein 1;
DE   AltName: Full=Coiled-coil serine-rich protein 1;
GN   Name=CCSER1; Synonyms=FAM190A, KIAA1680;
//
ID   CCSE2_HUMAN             Reviewed;         834 AA.
AC   Q9H7U1; B4DFY4; B4DQU9; B7WPE8; D3DWE2; Q8N6E9; Q9H2S0; Q9ULU1;
DE   RecName: Full=Serine-rich coiled-coil domain-containing protein 2;
DE   AltName: Full=Coiled-coil serine-rich protein 2;
DE   AltName: Full=Protein GCAP14 homolog;
GN   Name=CCSER2; Synonyms=FAM190B, KIAA1128; ORFNames=NPD012;
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
//
ID   CCS_HUMAN               Reviewed;         274 AA.
AC   O14618; Q2M366; Q8NEV0;
DE   RecName: Full=Copper chaperone for superoxide dismutase;
DE   AltName: Full=Superoxide dismutase copper chaperone;
GN   Name=CCS;
DR   GO; GO:0005507; F:copper ion binding; TAS:ProtInc.
DR   GO; GO:0005375; F:copper ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; TAS:Reactome.
DR   GO; GO:0004784; F:superoxide dismutase activity; IBA:RefGenome.
DR   GO; GO:0016532; F:superoxide dismutase copper chaperone activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; IBA:RefGenome.
DR   GO; GO:0035434; P:copper ion transmembrane transport; TAS:GOC.
DR   GO; GO:0015680; P:intracellular copper ion transport; IBA:RefGenome.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IEA:Ensembl.
DR   GO; GO:0019430; P:removal of superoxide radicals; IBA:RefGenome.
DR   GO; GO:0006801; P:superoxide metabolic process; TAS:ProtInc.
//
ID   CCYL1_HUMAN             Reviewed;         359 AA.
AC   Q8N7R7; Q6NX60;
DE   RecName: Full=Cyclin-Y-like protein 1;
GN   Name=CCNYL1;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
//
ID   CCYL2_HUMAN             Reviewed;         361 AA.
AC   Q5T2Q4;
DE   RecName: Full=Cyclin-Y-like protein 2;
GN   Name=CCNYL2; Synonyms=C10orf21;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
//
ID   CCYL3_HUMAN             Reviewed;         344 AA.
AC   P0C7X3; B5MCU7;
DE   RecName: Full=Putative cyclin-Y-like protein 3;
GN   Name=CCNYL3;
//
ID   CCZ1B_HUMAN             Reviewed;         482 AA.
AC   P86790; A2RU45; O95766; Q9UG65; Q9Y359;
DE   RecName: Full=Vacuolar fusion protein CCZ1 homolog B;
DE   AltName: Full=Vacuolar fusion protein CCZ1 homolog-like;
GN   Name=CCZ1B; Synonyms=C7orf28B;
//
ID   CCZ1_HUMAN              Reviewed;         482 AA.
AC   P86791; A2RU45; O95766; Q9UG65; Q9Y359;
DE   RecName: Full=Vacuolar fusion protein CCZ1 homolog;
GN   Name=CCZ1; Synonyms=C7orf28A; ORFNames=CGI-43;
//
ID   CD003_HUMAN             Reviewed;          66 AA.
AC   Q8WVX3; Q6J203;
DE   RecName: Full=Uncharacterized protein C4orf3;
DE   AltName: Full=Hepatitis C virus F protein-transactivated protein 1;
DE            Short=HCV F-transactivated protein 1;
GN   Name=C4orf3;
//
ID   CD006_HUMAN             Reviewed;          93 AA.
AC   Q99440; Q17R65;
DE   RecName: Full=Uncharacterized protein C4orf6;
DE   AltName: Full=Protein AC1;
GN   Name=C4orf6; Synonyms=AC1;
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   CD011_HUMAN             Reviewed;          94 AA.
AC   Q6W349;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00575;
GN   Name=LINC00575; Synonyms=C4orf11;
//
ID   CD017_HUMAN             Reviewed;         359 AA.
AC   Q53FE4; Q6FI84; Q6IS77; Q9H0D9;
DE   RecName: Full=Uncharacterized protein C4orf17;
GN   Name=C4orf17;
//
ID   CD019_HUMAN             Reviewed;         314 AA.
AC   Q8IY42; Q9NV03;
DE   RecName: Full=Uncharacterized protein C4orf19;
GN   Name=C4orf19;
//
ID   CD022_HUMAN             Reviewed;         233 AA.
AC   Q6V702; E7EQ13; Q6ZQY4; Q8N4G9;
DE   RecName: Full=Uncharacterized protein C4orf22;
GN   Name=C4orf22;
//
ID   CD026_HUMAN             Reviewed;         130 AA.
AC   Q17RF5; B4DTI3; E7ETQ0; Q8TEC3;
DE   RecName: Full=Uncharacterized protein C4orf26;
DE   Flags: Precursor;
GN   Name=C4orf26;
//
ID   CD027_HUMAN             Reviewed;         346 AA.
AC   Q9NWY4;
DE   RecName: Full=UPF0609 protein C4orf27;
GN   Name=C4orf27;
//
ID   CD029_HUMAN             Reviewed;         414 AA.
AC   Q0P651; A1A4W8; A1A4W9; Q9H7A7;
DE   RecName: Full=Uncharacterized protein C4orf29;
DE   Flags: Precursor;
GN   Name=C4orf29;
//
ID   CD033_HUMAN             Reviewed;         199 AA.
AC   Q8N1A6; D3DNY2; Q6PJF3; Q8NBC5;
DE   RecName: Full=UPF0462 protein C4orf33;
GN   Name=C4orf33;
//
ID   CD032_HUMAN             Reviewed;         132 AA.
AC   Q8N8J7; Q49A91; Q4W5C7; Q8TBF9;
DE   RecName: Full=Uncharacterized protein C4orf32;
GN   Name=C4orf32;
//
ID   CD036_HUMAN             Reviewed;         117 AA.
AC   Q96KX1;
DE   RecName: Full=Uncharacterized protein C4orf36;
GN   Name=C4orf36;
//
ID   CD045_HUMAN             Reviewed;         186 AA.
AC   Q96LM5; A8MPU3; C9J0T8;
DE   RecName: Full=Uncharacterized protein C4orf45;
GN   Name=C4orf45;
//
ID   CD046_HUMAN             Reviewed;         113 AA.
AC   Q504U0; B3KNH7;
DE   RecName: Full=Uncharacterized protein C4orf46;
GN   Name=C4orf46;
//
ID   CD047_HUMAN             Reviewed;         309 AA.
AC   A7E2U8; Q5BLP7;
DE   RecName: Full=UPF0602 protein C4orf47;
GN   Name=C4orf47; ORFNames=Chr4_1746;
//
ID   CD048_HUMAN             Reviewed;          95 AA.
AC   Q5BLP8; B6ZDN0; B7ZBI7; B7ZBI8;
DE   RecName: Full=Neuropeptide-like protein C4orf48;
DE   Flags: Precursor;
GN   Name=C4orf48; ORFNames=Chr4_55;
//
ID   CD050_HUMAN             Reviewed;         276 AA.
AC   Q6ZRC1;
DE   RecName: Full=Uncharacterized protein C4orf50;
GN   Name=C4orf50;
//
ID   CD051_HUMAN             Reviewed;         202 AA.
AC   C9J302;
DE   RecName: Full=Uncharacterized protein C4orf51;
GN   Name=C4orf51;
//
ID   CD109_HUMAN             Reviewed;        1445 AA.
AC   Q6YHK3; A5YKK4; B2R948; B3KW25; Q0P6K7; Q5SYA8; Q5XUM7; Q5XUM9;
AC   Q6MZI7; Q8N3A7; Q8N915; Q8TDJ2; Q8TDJ3;
DE   RecName: Full=CD109 antigen;
DE   AltName: Full=150 kDa TGF-beta-1-binding protein;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7;
DE   AltName: Full=Platelet-specific Gov antigen;
DE   AltName: Full=p180;
DE   AltName: Full=r150;
DE   AltName: CD_antigen=CD109;
DE   Flags: Precursor;
GN   Name=CD109; Synonyms=CPAMD7;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IPI:UniProt.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0061045; P:negative regulation of wound healing; IDA:UniProt.
//
ID   CD11A_HUMAN             Reviewed;         783 AA.
AC   Q9UQ88; O95227; O95228; O96012; Q12821; Q12853; Q12854; Q2TAJ0;
AC   Q5QPR0; Q5QPR1; Q5QPR2; Q9UBC4; Q9UBI3; Q9UEI1; Q9UEI2; Q9UP53;
AC   Q9UP54; Q9UP55; Q9UP56; Q9UQ86; Q9UQ87; Q9UQ89;
DE   RecName: Full=Cyclin-dependent kinase 11A;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division cycle 2-like protein kinase 2;
DE   AltName: Full=Cell division protein kinase 11A;
DE   AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA;
DE   AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L2;
GN   Name=CDK11A; Synonyms=CDC2L2, CDC2L3, PITSLREB;
DR   GuidetoPHARMACOLOGY; 1963; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004672; F:protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IEP:UniProtKB.
DR   GO; GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   CD11B_HUMAN             Reviewed;         795 AA.
AC   P21127; O95265; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530;
AC   Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59;
DE   RecName: Full=Cyclin-dependent kinase 11B;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division cycle 2-like protein kinase 1;
DE            Short=CLK-1;
DE   AltName: Full=Cell division protein kinase 11B;
DE   AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA;
DE   AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L1;
DE   AltName: Full=p58 CLK-1;
GN   Name=CDK11B; Synonyms=CDC2L1, CDK11, PITSLREA, PK58;
DR   GuidetoPHARMACOLOGY; 1964; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IEP:UniProtKB.
DR   GO; GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   CD123_HUMAN             Reviewed;         336 AA.
AC   O75794; A8JZZ7; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9;
DE   RecName: Full=Cell division cycle protein 123 homolog;
DE            Short=Protein D123;
DE   AltName: Full=HT-1080;
DE   AltName: Full=PZ32;
GN   Name=CDC123; Synonyms=C10orf7, D123;
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; ISS:HGNC.
//
ID   CD14_HUMAN              Reviewed;         375 AA.
AC   P08571; Q53XT5; Q96FR6; Q96L99; Q9UNS3;
DE   RecName: Full=Monocyte differentiation antigen CD14;
DE   AltName: Full=Myeloid cell-specific leucine-rich glycoprotein;
DE   AltName: CD_antigen=CD14;
DE   Contains:
DE     RecName: Full=Monocyte differentiation antigen CD14, urinary form;
DE   Contains:
DE     RecName: Full=Monocyte differentiation antigen CD14, membrane-bound form;
DE   Flags: Precursor;
GN   Name=CD14;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:MGI.
DR   GO; GO:0070891; F:lipoteichoic acid binding; IDA:MGI.
DR   GO; GO:0001847; F:opsonin receptor activity; TAS:BHF-UCL.
DR   GO; GO:0016019; F:peptidoglycan receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:MGI.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; IDA:MGI.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006909; P:phagocytosis; TAS:ProtInc.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:MGI.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   CD151_HUMAN             Reviewed;         253 AA.
AC   P48509; A8KAK8; E9PI15; Q14826; Q86U54; Q96TE3;
DE   RecName: Full=CD151 antigen;
DE   AltName: Full=GP27;
DE   AltName: Full=Membrane glycoprotein SFA-1;
DE   AltName: Full=Platelet-endothelial tetraspan antigen 3;
DE            Short=PETA-3;
DE   AltName: Full=Tetraspanin-24;
DE            Short=Tspan-24;
DE   AltName: CD_antigen=CD151;
GN   Name=CD151; Synonyms=TSPAN24;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
//
ID   CD15L_HUMAN             Reviewed;         281 AA.
AC   A8MXV6;
DE   RecName: Full=CMT1A duplicated region transcript 15 protein-like protein;
GN   Name=CDRT15L2;
//
ID   CD158_HUMAN             Reviewed;        1113 AA.
AC   Q5M9N0; Q8IYQ1; Q8N7D4; Q8N7E3;
DE   RecName: Full=Coiled-coil domain-containing protein 158;
GN   Name=CCDC158;
//
ID   CD166_HUMAN             Reviewed;         583 AA.
AC   Q13740; B2RNS3; B4DTU0; O60892; Q1HGM8; Q1HGM9; Q6PEY4; Q6ZS95;
DE   RecName: Full=CD166 antigen;
DE   AltName: Full=Activated leukocyte cell adhesion molecule;
DE   AltName: CD_antigen=CD166;
DE   Flags: Precursor;
GN   Name=ALCAM; Synonyms=MEMD;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD177_HUMAN             Reviewed;         437 AA.
AC   Q8N6Q3; Q711Q2; Q8NCV9; Q96QH1; Q9HDA5;
DE   RecName: Full=CD177 antigen;
DE   AltName: Full=Human neutrophil alloantigen 2a;
DE            Short=HNA-2a;
DE   AltName: Full=NB1 glycoprotein;
DE            Short=NB1 GP;
DE   AltName: Full=Polycythemia rubra vera protein 1;
DE            Short=PRV-1;
DE   AltName: CD_antigen=CD177;
DE   Flags: Precursor;
GN   Name=CD177; Synonyms=NB1, PRV1; ORFNames=UNQ595/PRO1181;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
//
ID   CD180_HUMAN             Reviewed;         661 AA.
AC   Q99467; B2R7Z7; Q32MM5;
DE   RecName: Full=CD180 antigen;
DE   AltName: Full=Lymphocyte antigen 64;
DE   AltName: Full=Radioprotective 105 kDa protein;
DE   AltName: CD_antigen=CD180;
DE   Flags: Precursor;
GN   Name=CD180; Synonyms=LY64, RP105;
DR   GO; GO:0002322; P:B cell proliferation involved in immune response; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IGI:MGI.
//
ID   CD19_HUMAN              Reviewed;         556 AA.
AC   P15391; A0N0P9; F5H635; Q96S68; Q9BRD6;
DE   RecName: Full=B-lymphocyte antigen CD19;
DE   AltName: Full=B-lymphocyte surface antigen B4;
DE   AltName: Full=Differentiation antigen CD19;
DE   AltName: Full=T-cell surface antigen Leu-12;
DE   AltName: CD_antigen=CD19;
DE   Flags: Precursor;
GN   Name=CD19;
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   CD1A_HUMAN              Reviewed;         327 AA.
AC   P06126; D3DVD7; Q13962; Q5TDJ8; Q9UMM4; Q9Y5M5;
DE   RecName: Full=T-cell surface glycoprotein CD1a;
DE   AltName: Full=T-cell surface antigen T6/Leu-6;
DE            Short=hTa1 thymocyte antigen;
DE   AltName: CD_antigen=CD1a;
DE   Flags: Precursor;
GN   Name=CD1A;
DR   GO; GO:0030881; F:beta-2-microglobulin binding; IBA:RefGenome.
DR   GO; GO:0030883; F:endogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0030884; F:exogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0071723; F:lipopeptide binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IBA:RefGenome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   CD1B_HUMAN              Reviewed;         333 AA.
AC   P29016; Q5TDK9; Q5TDL0; Q9UMM2;
DE   RecName: Full=T-cell surface glycoprotein CD1b;
DE   AltName: CD_antigen=CD1b;
DE   Flags: Precursor;
GN   Name=CD1B;
DR   GO; GO:0030881; F:beta-2-microglobulin binding; IBA:RefGenome.
DR   GO; GO:0030883; F:endogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0030884; F:exogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0071723; F:lipopeptide binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IBA:RefGenome.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   CD1C_HUMAN              Reviewed;         333 AA.
AC   P29017; Q5TDJ7; Q6IAS4; Q9UMM0; Q9UN96;
DE   RecName: Full=T-cell surface glycoprotein CD1c;
DE   AltName: CD_antigen=CD1c;
DE   Flags: Precursor;
GN   Name=CD1C;
DR   GO; GO:0030881; F:beta-2-microglobulin binding; IBA:RefGenome.
DR   GO; GO:0030883; F:endogenous lipid antigen binding; IDA:UniProtKB.
DR   GO; GO:0030884; F:exogenous lipid antigen binding; IDA:UniProtKB.
DR   GO; GO:0051861; F:glycolipid binding; IDA:UniProtKB.
DR   GO; GO:0071723; F:lipopeptide binding; IDA:UniProtKB.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IDA:UniProtKB.
//
ID   CD1D_HUMAN              Reviewed;         335 AA.
AC   P15813; D3DVD5; Q5W0J3; Q9UMM3; Q9Y5M4;
DE   RecName: Full=Antigen-presenting glycoprotein CD1d;
DE   AltName: Full=R3G1;
DE   AltName: CD_antigen=CD1d;
DE   Flags: Precursor;
GN   Name=CD1D;
DR   GO; GO:0030881; F:beta-2-microglobulin binding; TAS:UniProtKB.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0030883; F:endogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0030884; F:exogenous lipid antigen binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0030882; F:lipid antigen binding; IDA:BHF-UCL.
DR   GO; GO:0071723; F:lipopeptide binding; IBA:RefGenome.
DR   GO; GO:0004872; F:receptor activity; IC:UniProtKB.
DR   GO; GO:0048006; P:antigen processing and presentation, endogenous lipid antigen via MHC class Ib; IDA:UniProtKB.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IBA:RefGenome.
DR   GO; GO:0016045; P:detection of bacterium; TAS:UniProtKB.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0045089; P:positive regulation of innate immune response; TAS:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045058; P:T cell selection; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CD1E_HUMAN              Reviewed;         388 AA.
AC   P15812; B4DZV3; E7EP01; Q5TDJ9; Q5TDK3; Q5TDK4; Q5TDK5; Q5TDK6;
AC   Q5TDK8; Q5TDL1; Q712E4; Q712E5; Q712E6; Q712E7; Q712E8; Q712E9;
AC   Q712F0; Q712F1; Q712F2; Q712F3; Q712F4; Q712F5; Q96TD0; Q96TD1;
AC   Q9UMM1; Q9Y5M3;
DE   RecName: Full=T-cell surface glycoprotein CD1e, membrane-associated;
DE            Short=hCD1e;
DE   AltName: Full=R2G1;
DE   AltName: CD_antigen=CD1e;
DE   Contains:
DE     RecName: Full=T-cell surface glycoprotein CD1e, soluble;
DE              Short=sCD1e;
DE   Flags: Precursor;
GN   Name=CD1E;
DR   GO; GO:0030881; F:beta-2-microglobulin binding; IBA:RefGenome.
DR   GO; GO:0030883; F:endogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0030884; F:exogenous lipid antigen binding; IBA:RefGenome.
DR   GO; GO:0071723; F:lipopeptide binding; IBA:RefGenome.
DR   GO; GO:0048007; P:antigen processing and presentation, exogenous lipid antigen via MHC class Ib; IBA:RefGenome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   CD209_HUMAN             Reviewed;         404 AA.
AC   Q9NNX6; A8KAM4; A8MVQ9; G5E9C4; Q2TB19; Q96QP7; Q96QP8; Q96QP9;
AC   Q96QQ0; Q96QQ1; Q96QQ2; Q96QQ3; Q96QQ4; Q96QQ5; Q96QQ6; Q96QQ7;
AC   Q96QQ8;
DE   RecName: Full=CD209 antigen;
DE   AltName: Full=C-type lectin domain family 4 member L;
DE   AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 1;
DE            Short=DC-SIGN;
DE            Short=DC-SIGN1;
DE   AltName: CD_antigen=CD209;
GN   Name=CD209; Synonyms=CLEC4L;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0005537; F:mannose binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0046790; F:virion binding; TAS:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; NAS:UniProtKB.
DR   GO; GO:0009988; P:cell-cell recognition; TAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:UniProtKB.
DR   GO; GO:0046968; P:peptide antigen transport; NAS:UniProtKB.
DR   GO; GO:0042129; P:regulation of T cell proliferation; IDA:MGI.
DR   GO; GO:0019079; P:viral genome replication; NAS:UniProtKB.
DR   GO; GO:0019062; P:virion attachment to host cell; TAS:UniProtKB.
//
ID   CD20B_HUMAN             Reviewed;         519 AA.
AC   Q86Y33; B7WNV8; B9EGL8; C9J6X8; C9JHE9; C9JKL5; Q86Y31; Q86Y32;
AC   Q8IUZ8; Q8N1S1; Q8NG56;
DE   RecName: Full=Cell division cycle protein 20 homolog B;
GN   Name=CDC20B; ORFNames=G6VTS76519;
//
ID   CD20_HUMAN              Reviewed;         297 AA.
AC   P11836; A6NMS4; P08984; Q13963;
DE   RecName: Full=B-lymphocyte antigen CD20;
DE   AltName: Full=B-lymphocyte surface antigen B1;
DE   AltName: Full=Bp35;
DE   AltName: Full=Leukocyte surface antigen Leu-16;
DE   AltName: Full=Membrane-spanning 4-domains subfamily A member 1;
DE   AltName: CD_antigen=CD20;
GN   Name=MS4A1; Synonyms=CD20;
DR   GuidetoPHARMACOLOGY; 2628; -.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0042100; P:B cell proliferation; NAS:UniProt.
DR   GO; GO:0006959; P:humoral immune response; NAS:UniProt.
//
ID   CD226_HUMAN             Reviewed;         336 AA.
AC   Q15762; B2R818;
DE   RecName: Full=CD226 antigen;
DE   AltName: Full=DNAX accessory molecule 1;
DE            Short=DNAM-1;
DE   AltName: CD_antigen=CD226;
DE   Flags: Precursor;
GN   Name=CD226; Synonyms=DNAM1;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0008037; P:cell recognition; TAS:BHF-UCL.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0060369; P:positive regulation of Fc receptor mediated stimulatory signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0002891; P:positive regulation of immunoglobulin mediated immune response; IDA:BHF-UCL.
DR   GO; GO:0033005; P:positive regulation of mast cell activation; IDA:BHF-UCL.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IMP:BHF-UCL.
DR   GO; GO:0002860; P:positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; IMP:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD22_HUMAN              Reviewed;         847 AA.
AC   P20273; F5GYU4; F5H7U3; O95699; O95701; O95702; O95703; Q01665;
AC   Q32M46; Q92872; Q92873; Q9UQA6; Q9UQA7; Q9UQA8; Q9UQA9; Q9UQB0;
AC   Q9Y2A6;
DE   RecName: Full=B-cell receptor CD22;
DE   AltName: Full=B-lymphocyte cell adhesion molecule;
DE            Short=BL-CAM;
DE   AltName: Full=Sialic acid-binding Ig-like lectin 2;
DE            Short=Siglec-2;
DE   AltName: Full=T-cell surface antigen Leu-14;
DE   AltName: CD_antigen=CD22;
DE   Flags: Precursor;
GN   Name=CD22; Synonyms=SIGLEC2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
//
ID   CD244_HUMAN             Reviewed;         370 AA.
AC   Q9BZW8; Q5VYI2; Q5VYI6; Q5VYI7; Q96T47; Q9NQD2; Q9NQD3; Q9Y288;
DE   RecName: Full=Natural killer cell receptor 2B4;
DE   AltName: Full=NK cell activation-inducing ligand;
DE            Short=NAIL;
DE   AltName: Full=NK cell type I receptor protein 2B4;
DE            Short=NKR2B4;
DE            Short=h2B4;
DE   AltName: Full=SLAM family member 4;
DE            Short=SLAMF4;
DE   AltName: Full=Signaling lymphocytic activation molecule 4;
DE   AltName: CD_antigen=CD244;
DE   Flags: Precursor;
GN   Name=CD244; Synonyms=2B4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD248_HUMAN             Reviewed;         757 AA.
AC   Q9HCU0; Q2M2V5; Q3SX55; Q96KB6;
DE   RecName: Full=Endosialin;
DE   AltName: Full=Tumor endothelial marker 1;
DE   AltName: CD_antigen=CD248;
DE   Flags: Precursor;
GN   Name=CD248; Synonyms=CD164L1, TEM1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0060033; P:anatomical structure regression; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IEA:Ensembl.
//
ID   CD276_HUMAN             Reviewed;         534 AA.
AC   Q5ZPR3; Q6P5Y4; Q6UXI2; Q8NBI8; Q8NC34; Q8NCB6; Q9BXR1;
DE   RecName: Full=CD276 antigen;
DE   AltName: Full=4Ig-B7-H3;
DE   AltName: Full=B7 homolog 3;
DE            Short=B7-H3;
DE   AltName: Full=Costimulatory molecule;
DE   AltName: CD_antigen=CD276;
DE   Flags: Precursor;
GN   Name=CD276; Synonyms=B7H3; ORFNames=PSEC0249, UNQ309/PRO352;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; NAS:HGNC.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:HGNC.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:HGNC.
DR   GO; GO:0050776; P:regulation of immune response; NAS:HGNC.
DR   GO; GO:0042110; P:T cell activation; IDA:UniProtKB.
//
ID   CD24_HUMAN              Reviewed;          80 AA.
AC   P25063; Q16257; Q53XS0;
DE   RecName: Full=Signal transducer CD24;
DE   AltName: Full=Small cell lung carcinoma cluster 4 antigen;
DE   AltName: CD_antigen=CD24;
DE   Flags: Precursor;
GN   Name=CD24; Synonyms=CD24A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0032597; P:B cell receptor transport into membrane raft; IDA:UniProtKB.
DR   GO; GO:0001775; P:cell activation; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0032600; P:chemokine receptor transport out of membrane raft; ISS:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0072139; P:glomerular parietal epithelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IC:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; NAS:UniProtKB.
DR   GO; GO:0032913; P:negative regulation of transforming growth factor beta3 production; IMP:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:2000768; P:positive regulation of nephron tubule epithelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0001959; P:regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030856; P:regulation of epithelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0042325; P:regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045730; P:respiratory burst; IDA:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IEP:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; ISS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; NAS:UniProtKB.
//
ID   CD27_HUMAN              Reviewed;         260 AA.
AC   P26842; B2RDZ0;
DE   RecName: Full=CD27 antigen;
DE   AltName: Full=CD27L receptor;
DE   AltName: Full=T-cell activation antigen CD27;
DE   AltName: Full=T14;
DE   AltName: Full=Tumor necrosis factor receptor superfamily member 7;
DE   AltName: CD_antigen=CD27;
DE   Flags: Precursor;
GN   Name=CD27; Synonyms=TNFRSF7;
DR   GuidetoPHARMACOLOGY; 1876; -.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:GOC.
DR   GO; GO:0070233; P:negative regulation of T cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.
DR   GO; GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; NAS:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
//
ID   CD28_HUMAN              Reviewed;         220 AA.
AC   P10747; A8KAC1; Q13964; Q52M23; Q70WG0; Q8NI54; Q8NI55; Q8NI56;
AC   Q8WXJ2; Q9BYV0;
DE   RecName: Full=T-cell-specific surface glycoprotein CD28;
DE   AltName: Full=TP44;
DE   AltName: CD_antigen=CD28;
DE   Flags: Precursor;
GN   Name=CD28;
DR   GO; GO:0015026; F:coreceptor activity; TAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; NAS:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0042089; P:cytokine biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006959; P:humoral immune response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0002863; P:positive regulation of inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IDA:GOC.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; NAS:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; NAS:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0045066; P:regulatory T cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CD2A1_HUMAN             Reviewed;         156 AA.
AC   P42771; A5X2G7; D3DRK1; O95440; Q15191; Q5VVJ5; Q96B52; Q9NP05;
DE   RecName: Full=Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3;
DE   AltName: Full=Cyclin-dependent kinase 4 inhibitor A;
DE            Short=CDK4I;
DE   AltName: Full=Multiple tumor suppressor 1;
DE            Short=MTS-1;
DE   AltName: Full=p16-INK4a;
DE            Short=p16-INK4;
DE            Short=p16INK4A;
GN   Name=CDKN2A; Synonyms=CDKN2, MTS1;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0051059; F:NF-kappaB binding; IDA:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0000075; P:cell cycle checkpoint; IMP:HGNC.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:2000774; P:positive regulation of cellular senescence; IMP:UniProtKB.
DR   GO; GO:2000111; P:positive regulation of macrophage apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.
DR   GO; GO:0090399; P:replicative senescence; IMP:BHF-UCL.
DR   GO; GO:0035986; P:senescence-associated heterochromatin focus assembly; IMP:UniProtKB.
//
ID   CD2A2_HUMAN             Reviewed;         132 AA.
AC   Q8N726; D3DRK2; Q13195; Q13399; Q16360; Q7KZR9;
DE   RecName: Full=Cyclin-dependent kinase inhibitor 2A, isoform 4;
DE   AltName: Full=p14ARF;
DE   AltName: Full=p19ARF;
GN   Name=CDKN2A; Synonyms=CDKN2, MLM;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0097371; F:MDM2/MDM4 family protein binding; IPI:BHF-UCL.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0055105; F:ubiquitin-protein ligase inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IMP:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0090398; P:cellular senescence; IMP:BHF-UCL.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0033088; P:negative regulation of immature T cell proliferation in thymus; ISS:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; ISS:BHF-UCL.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IDA:BHF-UCL.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:1902510; P:regulation of apoptotic DNA fragmentation; IMP:BHF-UCL.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0046825; P:regulation of protein export from nucleus; IMP:BHF-UCL.
DR   GO; GO:0031647; P:regulation of protein stability; ISS:BHF-UCL.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048103; P:somatic stem cell division; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CD2AP_HUMAN             Reviewed;         639 AA.
AC   Q9Y5K6; A6NL34; Q5VYA3; Q9UG97;
DE   RecName: Full=CD2-associated protein;
DE   AltName: Full=Adapter protein CMS;
DE   AltName: Full=Cas ligand with multiple SH3 domains;
GN   Name=CD2AP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0048259; P:regulation of receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc.
DR   GO; GO:0016050; P:vesicle organization; IEA:Ensembl.
//
ID   CD2B2_HUMAN             Reviewed;         341 AA.
AC   O95400; B2RDX2; Q9ULP2;
DE   RecName: Full=CD2 antigen cytoplasmic tail-binding protein 2;
DE            Short=CD2 cytoplasmic domain-binding protein 2;
DE            Short=CD2 tail-binding protein 2;
DE   AltName: Full=U5 snRNP 52K protein;
DE            Short=U5-52K;
GN   Name=CD2BP2; Synonyms=KIAA1178;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; NAS:BHF-UCL.
//
ID   CD2_HUMAN               Reviewed;         351 AA.
AC   P06729; Q96TE5;
DE   RecName: Full=T-cell surface antigen CD2;
DE   AltName: Full=Erythrocyte receptor;
DE   AltName: Full=LFA-2;
DE   AltName: Full=LFA-3 receptor;
DE   AltName: Full=Rosette receptor;
DE   AltName: Full=T-cell surface antigen T11/Leu-5;
DE   AltName: CD_antigen=CD2;
DE   Flags: Precursor;
GN   Name=CD2; Synonyms=SRBC;
DR   GuidetoPHARMACOLOGY; 2600; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProt.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IDA:UniProt.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0001766; P:membrane raft polarization; TAS:UniProtKB.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
DR   GO; GO:1902715; P:positive regulation of interferon-gamma secretion; IDA:UniProt.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IMP:UniProt.
DR   GO; GO:0030887; P:positive regulation of myeloid dendritic cell activation; NAS:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:UniProt.
DR   GO; GO:0045580; P:regulation of T cell differentiation; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
//
ID   CD302_HUMAN             Reviewed;         232 AA.
AC   Q8IX05; A8K5G4; B4E2T9; Q15009;
DE   RecName: Full=CD302 antigen;
DE   AltName: Full=C-type lectin BIMLEC;
DE   AltName: Full=C-type lectin domain family 13 member A;
DE   AltName: Full=DEC205-associated C-type lectin 1;
DE   AltName: Full=Type I transmembrane C-type lectin receptor DCL-1;
DE   AltName: CD_antigen=CD302;
DE   Flags: Precursor;
GN   Name=CD302; Synonyms=CLEC13A, DCL1, KIAA0022;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006909; P:phagocytosis; IDA:MGI.
//
ID   CD320_HUMAN             Reviewed;         282 AA.
AC   Q9NPF0; B2RDS5; D6W668; F5H6D3; Q53HF7;
DE   RecName: Full=CD320 antigen;
DE   AltName: Full=8D6 antigen;
DE   AltName: Full=FDC-signaling molecule 8D6;
DE            Short=FDC-SM-8D6;
DE   AltName: Full=Transcobalamin receptor;
DE            Short=TCblR;
DE   AltName: CD_antigen=CD320;
DE   Flags: Precursor;
GN   Name=CD320; Synonyms=8D6A; ORFNames=UNQ198/PRO224;
DR   GO; GO:0031419; F:cobalamin binding; IDA:MGI.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   CD33_HUMAN              Reviewed;         364 AA.
AC   P20138; B4E3P8; C9JEN7; F8WAL2; Q8TD24;
DE   RecName: Full=Myeloid cell surface antigen CD33;
DE   AltName: Full=Sialic acid-binding Ig-like lectin 3;
DE            Short=Siglec-3;
DE   AltName: Full=gp67;
DE   AltName: CD_antigen=CD33;
DE   Flags: Precursor;
GN   Name=CD33; Synonyms=SIGLEC3;
DR   GuidetoPHARMACOLOGY; 2601; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD34_HUMAN              Reviewed;         385 AA.
AC   P28906; A8K664; Q15970; Q15971; Q5JTA3; Q5JTA4; Q9UJB1;
DE   RecName: Full=Hematopoietic progenitor cell antigen CD34;
DE   AltName: CD_antigen=CD34;
DE   Flags: Precursor;
GN   Name=CD34;
DR   GO; GO:0030246; F:carbohydrate binding; IDA:HGNC.
DR   GO; GO:0043199; F:sulfate binding; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0048870; P:cell motility; IEP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:HGNC.
DR   GO; GO:0001935; P:endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0003158; P:endothelium development; IEP:UniProtKB.
DR   GO; GO:0071971; P:extracellular vesicular exosome assembly; IDA:UniProtKB.
DR   GO; GO:0072011; P:glomerular endothelium development; IEP:UniProtKB.
DR   GO; GO:0003094; P:glomerular filtration; IEP:UniProtKB.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IMP:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IMP:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; ISS:HGNC.
DR   GO; GO:0035759; P:mesangial cell-matrix adhesion; ISS:UniProtKB.
DR   GO; GO:0072254; P:metanephric glomerular mesangial cell differentiation; IEP:UniProtKB.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IDA:UniProtKB.
DR   GO; GO:1900035; P:negative regulation of cellular response to heat; IDA:UniProtKB.
DR   GO; GO:1900038; P:negative regulation of cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:1900041; P:negative regulation of interleukin-2 secretion; IMP:UniProtKB.
DR   GO; GO:1901215; P:negative regulation of neuron death; IDA:UniProtKB.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0038001; P:paracrine signaling; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEP:UniProtKB.
DR   GO; GO:1900168; P:positive regulation of glial cell line-derived neurotrophic factor secretion; IDA:UniProtKB.
DR   GO; GO:0071657; P:positive regulation of granulocyte colony-stimulating factor production; IDA:UniProtKB.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IDA:UniProtKB.
DR   GO; GO:0042482; P:positive regulation of odontogenesis; IDA:UniProtKB.
DR   GO; GO:0071636; P:positive regulation of transforming growth factor beta production; IDA:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IEP:UniProtKB.
DR   GO; GO:0072089; P:stem cell proliferation; IEP:UniProtKB.
DR   GO; GO:0001894; P:tissue homeostasis; IDA:UniProtKB.
DR   GO; GO:0060290; P:transdifferentiation; IEP:UniProtKB.
DR   GO; GO:0061042; P:vascular wound healing; IEP:UniProtKB.
//
ID   CD36_HUMAN              Reviewed;         472 AA.
AC   P16671; Q13966; Q16093; Q8TCV7; Q9BPZ8; Q9BQC2; Q9BZM8; Q9BZN3;
AC   Q9BZN4; Q9BZN5;
DE   RecName: Full=Platelet glycoprotein 4;
DE   AltName: Full=Fatty acid translocase;
DE            Short=FAT;
DE   AltName: Full=Glycoprotein IIIb;
DE            Short=GPIIIB;
DE   AltName: Full=Leukocyte differentiation antigen CD36;
DE   AltName: Full=PAS IV;
DE   AltName: Full=PAS-4;
DE   AltName: Full=Platelet collagen receptor;
DE   AltName: Full=Platelet glycoprotein IV;
DE            Short=GPIV;
DE   AltName: Full=Thrombospondin receptor;
DE   AltName: CD_antigen=CD36;
GN   Name=CD36; Synonyms=GP3B, GP4;
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0008289; F:lipid binding; IDA:BHF-UCL.
DR   GO; GO:0071813; F:lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0070892; F:lipoteichoic acid receptor activity; IEA:Ensembl.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:BHF-UCL.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IMP:BHF-UCL.
DR   GO; GO:0070053; F:thrombospondin receptor activity; ISS:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; ISS:BHF-UCL.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071221; P:cellular response to bacterial lipopeptide; IEA:Ensembl.
DR   GO; GO:0071447; P:cellular response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; IEA:Ensembl.
DR   GO; GO:0019934; P:cGMP-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0030301; P:cholesterol transport; ISS:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0019915; P:lipid storage; IMP:BHF-UCL.
DR   GO; GO:0042953; P:lipoprotein transport; IMP:BHF-UCL.
DR   GO; GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0055096; P:low-density lipoprotein particle mediated signaling; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0042992; P:negative regulation of transcription factor import into nucleus; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IDA:BHF-UCL.
DR   GO; GO:0006910; P:phagocytosis, recognition; IEA:Ensembl.
DR   GO; GO:0034381; P:plasma lipoprotein particle clearance; ISS:BHF-UCL.
DR   GO; GO:0015911; P:plasma membrane long-chain fatty acid transport; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IEA:Ensembl.
DR   GO; GO:2000334; P:positive regulation of blood microparticle formation; IEA:Ensembl.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; IEA:Ensembl.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0060100; P:positive regulation of phagocytosis, engulfment; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:GOC.
DR   GO; GO:2000121; P:regulation of removal of superoxide radicals; IEA:Ensembl.
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   CD37L_HUMAN             Reviewed;         337 AA.
AC   Q7L3B6; B1AL70; Q9NWS3; Q9NX16;
DE   RecName: Full=Hsp90 co-chaperone Cdc37-like 1;
DE   AltName: Full=Hsp90-associating relative of Cdc37;
GN   Name=CDC37L1; Synonyms=CDC37B, HARC;
//
ID   CD37_HUMAN              Reviewed;         281 AA.
AC   P11049; B4DVC1; Q3KPF9;
DE   RecName: Full=Leukocyte antigen CD37;
DE   AltName: Full=Tetraspanin-26;
DE            Short=Tspan-26;
DE   AltName: CD_antigen=CD37;
GN   Name=CD37; Synonyms=TSPAN26;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030886; P:negative regulation of myeloid dendritic cell activation; IEA:Ensembl.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IEA:Ensembl.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:Ensembl.
DR   GO; GO:0002920; P:regulation of humoral immune response; IEA:Ensembl.
//
ID   CD38_HUMAN              Reviewed;         300 AA.
AC   P28907; O00121; O00122; Q96HY4;
DE   RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;
DE            EC=3.2.2.6;
DE   AltName: Full=2'-phospho-ADP-ribosyl cyclase;
DE   AltName: Full=2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;
DE            EC=2.4.99.20;
DE   AltName: Full=2'-phospho-cyclic-ADP-ribose transferase;
DE   AltName: Full=ADP-ribosyl cyclase 1;
DE            Short=ADPRC 1;
DE   AltName: Full=Cyclic ADP-ribose hydrolase 1;
DE            Short=cADPr hydrolase 1;
DE   AltName: Full=T10;
DE   AltName: CD_antigen=CD38;
GN   Name=CD38;
DR   GO; GO:0050135; F:NAD(P)+ nucleosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003953; F:NAD+ nucleosidase activity; IEA:Ensembl.
DR   GO; GO:0016849; F:phosphorus-oxygen lyase activity; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0033194; P:response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CD3D_HUMAN              Reviewed;         171 AA.
AC   P04234; A8MVP6;
DE   RecName: Full=T-cell surface glycoprotein CD3 delta chain;
DE   AltName: Full=T-cell receptor T3 delta chain;
DE   AltName: CD_antigen=CD3d;
DE   Flags: Precursor;
GN   Name=CD3D; Synonyms=T3D;
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IC:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IC:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045059; P:positive thymic T cell selection; ISS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0030217; P:T cell differentiation; IDA:MGI.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   CD3E_HUMAN              Reviewed;         207 AA.
AC   P07766; A8K997;
DE   RecName: Full=T-cell surface glycoprotein CD3 epsilon chain;
DE   AltName: Full=T-cell surface antigen T3/Leu-4 epsilon chain;
DE   AltName: CD_antigen=CD3e;
DE   Flags: Precursor;
GN   Name=CD3E; Synonyms=T3E;
DR   GuidetoPHARMACOLOGY; 2742; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; NAS:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0042608; F:T cell receptor binding; NAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0002669; P:positive regulation of T cell anergy; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0007172; P:signal complex assembly; TAS:ProtInc.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   CD3G_HUMAN              Reviewed;         182 AA.
AC   P09693; Q2HIZ6;
DE   RecName: Full=T-cell surface glycoprotein CD3 gamma chain;
DE   AltName: Full=T-cell receptor T3 gamma chain;
DE   AltName: CD_antigen=CD3g;
DE   Flags: Precursor;
GN   Name=CD3G; Synonyms=T3G;
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0042608; F:T cell receptor binding; NAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IMP:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IMP:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0070228; P:regulation of lymphocyte apoptotic process; IMP:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   CD3Z_HUMAN              Reviewed;         164 AA.
AC   P20963; B1AK49; Q5VX13; Q8TAX4;
DE   RecName: Full=T-cell surface glycoprotein CD3 zeta chain;
DE   AltName: Full=T-cell receptor T3 zeta chain;
DE   AltName: CD_antigen=CD247;
DE   Flags: Precursor;
GN   Name=CD247; Synonyms=CD3Z, T3Z, TCRZ;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CD40L_HUMAN             Reviewed;         261 AA.
AC   P29965;
DE   RecName: Full=CD40 ligand;
DE            Short=CD40-L;
DE   AltName: Full=T-cell antigen Gp39;
DE   AltName: Full=TNF-related activation protein;
DE            Short=TRAP;
DE   AltName: Full=Tumor necrosis factor ligand superfamily member 5;
DE   AltName: CD_antigen=CD154;
DE   Contains:
DE     RecName: Full=CD40 ligand, membrane form;
DE   Contains:
DE     RecName: Full=CD40 ligand, soluble form;
GN   Name=CD40LG; Synonyms=CD40L, TNFSF5, TRAP;
DR   GO; GO:0005174; F:CD40 receptor binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0042100; P:B cell proliferation; IDA:UniProtKB.
DR   GO; GO:0048305; P:immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; IDA:UniProtKB.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0051023; P:regulation of immunoglobulin secretion; IEA:Ensembl.
//
ID   CD44_HUMAN              Reviewed;         742 AA.
AC   P16070; A5YRN9; B6EAT9; D3DR12; D3DR13; O95370; P22511; Q04858;
AC   Q13419; Q13957; Q13958; Q13959; Q13960; Q13961; Q13967; Q13968;
AC   Q13980; Q15861; Q16064; Q16065; Q16066; Q16208; Q16522; Q86T72;
AC   Q86Z27; Q8N694; Q92493; Q96J24; Q9H5A5; Q9UC28; Q9UC29; Q9UC30;
AC   Q9UCB0; Q9UJ36;
DE   RecName: Full=CD44 antigen;
DE   AltName: Full=CDw44;
DE   AltName: Full=Epican;
DE   AltName: Full=Extracellular matrix receptor III;
DE            Short=ECMR-III;
DE   AltName: Full=GP90 lymphocyte homing/adhesion receptor;
DE   AltName: Full=HUTCH-I;
DE   AltName: Full=Heparan sulfate proteoglycan;
DE   AltName: Full=Hermes antigen;
DE   AltName: Full=Hyaluronate receptor;
DE   AltName: Full=Phagocytic glycoprotein 1;
DE            Short=PGP-1;
DE   AltName: Full=Phagocytic glycoprotein I;
DE            Short=PGP-I;
DE   AltName: CD_antigen=CD44;
DE   Flags: Precursor;
GN   Name=CD44; Synonyms=LHR, MDU2, MDU3, MIC4;
DR   GO; GO:0005518; F:collagen binding; NAS:UniProtKB.
DR   GO; GO:0005540; F:hyaluronic acid binding; IDA:UniProtKB.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060442; P:branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0051216; P:cartilage development; IEP:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; IDA:UniProtKB.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0070487; P:monocyte aggregation; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:1900625; P:positive regulation of monocyte aggregation; IMP:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0002246; P:wound healing involved in inflammatory response; IEA:Ensembl.
//
ID   CD47_HUMAN              Reviewed;         323 AA.
AC   Q08722; A8K198; D3DN59; Q53Y71; Q96A60;
DE   RecName: Full=Leukocyte surface antigen CD47;
DE   AltName: Full=Antigenic surface determinant protein OA3;
DE   AltName: Full=Integrin-associated protein;
DE            Short=IAP;
DE   AltName: Full=Protein MER6;
DE   AltName: CD_antigen=CD47;
DE   Flags: Precursor;
GN   Name=CD47; Synonyms=MER6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070053; F:thrombospondin receptor activity; IPI:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0008228; P:opsonization; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IDA:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
//
ID   CD48_HUMAN              Reviewed;         243 AA.
AC   P09326; Q5U055;
DE   RecName: Full=CD48 antigen;
DE   AltName: Full=B-lymphocyte activation marker BLAST-1;
DE   AltName: Full=BCM1 surface antigen;
DE   AltName: Full=Leukocyte antigen MEM-102;
DE   AltName: Full=SLAM family member 2;
DE            Short=SLAMF2;
DE   AltName: Full=Signaling lymphocytic activation molecule 2;
DE   AltName: Full=TCT.1;
DE   AltName: CD_antigen=CD48;
DE   Flags: Precursor;
GN   Name=CD48; Synonyms=BCM1, BLAST1;
DR   GO; GO:0003823; F:antigen binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0045576; P:mast cell activation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
//
ID   CD4_HUMAN               Reviewed;         458 AA.
AC   P01730; B2R737; D3DUS5; Q4ZGK2; Q5U066; Q9UDE5;
DE   RecName: Full=T-cell surface glycoprotein CD4;
DE   AltName: Full=T-cell surface antigen T4/Leu-3;
DE   AltName: CD_antigen=CD4;
DE   Flags: Precursor;
GN   Name=CD4;
DR   GO; GO:0015026; F:coreceptor activity; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProtKB.
DR   GO; GO:0042289; F:MHC class II protein binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
DR   GO; GO:0030260; P:entry into host cell; TAS:Reactome.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006948; P:induction by virus of host cell-cell fusion; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032507; P:maintenance of protein location in cell; IDA:MGI.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0045234; P:protein palmitoleylation; IDA:MGI.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0050863; P:regulation of T cell activation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0030217; P:T cell differentiation; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045058; P:T cell selection; IDA:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CD52_HUMAN              Reviewed;          61 AA.
AC   P31358; Q5T138; Q9BW46;
DE   RecName: Full=CAMPATH-1 antigen;
DE   AltName: Full=CDw52;
DE   AltName: Full=Cambridge pathology 1 antigen;
DE   AltName: Full=Epididymal secretory protein E5;
DE   AltName: Full=Human epididymis-specific protein 5;
DE            Short=He5;
DE   AltName: CD_antigen=CD52;
DE   Flags: Precursor;
GN   Name=CD52; Synonyms=CDW52, HE5;
DR   GuidetoPHARMACOLOGY; 2602; -.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0045730; P:respiratory burst; NAS:UniProtKB.
//
ID   CD53_HUMAN              Reviewed;         219 AA.
AC   P19397; B2R905; Q5U0D6;
DE   RecName: Full=Leukocyte surface antigen CD53;
DE   AltName: Full=Cell surface glycoprotein CD53;
DE   AltName: Full=Tetraspanin-25;
DE            Short=Tspan-25;
DE   AltName: CD_antigen=CD53;
GN   Name=CD53; Synonyms=MOX44, TSPAN25;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:1901741; P:positive regulation of myoblast fusion; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CD59_HUMAN              Reviewed;         128 AA.
AC   P13987;
DE   RecName: Full=CD59 glycoprotein;
DE   AltName: Full=1F5 antigen;
DE   AltName: Full=20 kDa homologous restriction factor;
DE            Short=HRF-20;
DE            Short=HRF20;
DE   AltName: Full=MAC-inhibitory protein;
DE            Short=MAC-IP;
DE   AltName: Full=MEM43 antigen;
DE   AltName: Full=Membrane attack complex inhibition factor;
DE            Short=MACIF;
DE   AltName: Full=Membrane inhibitor of reactive lysis;
DE            Short=MIRL;
DE   AltName: Full=Protectin;
DE   AltName: CD_antigen=CD59;
DE   Flags: Precursor;
GN   Name=CD59; Synonyms=MIC11, MIN1, MIN2, MIN3, MSK21;
DR   GO; GO:0001848; F:complement binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0001775; P:cell activation; IBA:RefGenome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001971; P:negative regulation of activation of membrane attack complex; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CD5L_HUMAN              Reviewed;         347 AA.
AC   O43866; A8K7M5; Q6UX63;
DE   RecName: Full=CD5 antigen-like;
DE   AltName: Full=CT-2;
DE   AltName: Full=IgM-associated peptide;
DE   AltName: Full=SP-alpha;
DE   Flags: Precursor;
GN   Name=CD5L; Synonyms=API6; ORFNames=UNQ203/PRO229;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   CD5R1_HUMAN             Reviewed;         307 AA.
AC   Q15078; E1P664; Q5U0G3;
DE   RecName: Full=Cyclin-dependent kinase 5 activator 1;
DE            Short=CDK5 activator 1;
DE   AltName: Full=Cyclin-dependent kinase 5 regulatory subunit 1;
DE   AltName: Full=TPKII regulatory subunit;
DE   Contains:
DE     RecName: Full=Cyclin-dependent kinase 5 activator 1, p35;
DE              Short=p35;
DE   Contains:
DE     RecName: Full=Cyclin-dependent kinase 5 activator 1, p25;
DE              Short=p25;
DE     AltName: Full=Tau protein kinase II 23 kDa subunit;
DE              Short=p23;
DE   Flags: Precursor;
GN   Name=CDK5R1; Synonyms=CDK5R, NCK5A;
DR   GO; GO:0045296; F:cadherin binding; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0016534; F:cyclin-dependent protein kinase 5 activator activity; IEA:Ensembl.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0016301; F:kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0007413; P:axonal fasciculation; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; IEA:Ensembl.
DR   GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:DFLAT.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0045664; P:regulation of neuron differentiation; NAS:UniProtKB.
DR   GO; GO:0033136; P:serine phosphorylation of STAT3 protein; IEA:Ensembl.
DR   GO; GO:0021722; P:superior olivary nucleus maturation; IEA:Ensembl.
//
ID   CD5R2_HUMAN             Reviewed;         367 AA.
AC   Q13319; Q4ZFW6;
DE   RecName: Full=Cyclin-dependent kinase 5 activator 2;
DE            Short=CDK5 activator 2;
DE   AltName: Full=Cyclin-dependent kinase 5 regulatory subunit 2;
DE   AltName: Full=p39;
DE   AltName: Full=p39I;
DE   Flags: Precursor;
GN   Name=CDK5R2; Synonyms=NCK5AI;
DR   GO; GO:0016534; F:cyclin-dependent protein kinase 5 activator activity; IEA:Ensembl.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0021722; P:superior olivary nucleus maturation; IEA:Ensembl.
//
ID   CD5_HUMAN               Reviewed;         495 AA.
AC   P06127; A0N0P4; A8K9I3;
DE   RecName: Full=T-cell surface glycoprotein CD5;
DE   AltName: Full=Lymphocyte antigen T1/Leu-1;
DE   AltName: CD_antigen=CD5;
DE   Flags: Precursor;
GN   Name=CD5; Synonyms=LEU1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0008037; P:cell recognition; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
//
ID   CD63_HUMAN              Reviewed;         238 AA.
AC   P08962; F8VZE2; Q5TZP3; Q8N6Z9; Q9UCG6;
DE   RecName: Full=CD63 antigen;
DE   AltName: Full=Granulophysin;
DE   AltName: Full=Lysosomal-associated membrane protein 3;
DE            Short=LAMP-3;
DE   AltName: Full=Melanoma-associated antigen ME491;
DE   AltName: Full=OMA81H;
DE   AltName: Full=Ocular melanoma-associated antigen;
DE   AltName: Full=Tetraspanin-30;
DE            Short=Tspan-30;
DE   AltName: CD_antigen=CD63;
GN   Name=CD63; Synonyms=MLA1, TSPAN30;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034613; P:cellular protein localization; IDA:MGI.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:2000680; P:regulation of rubidium ion transport; IDA:MGI.
//
ID   CD68_HUMAN              Reviewed;         354 AA.
AC   P34810; B4DVT4; Q53HR6; Q53XI3; Q96BI7;
DE   RecName: Full=Macrosialin;
DE   AltName: Full=Gp110;
DE   AltName: CD_antigen=CD68;
DE   Flags: Precursor;
GN   Name=CD68;
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
//
ID   CD69_HUMAN              Reviewed;         199 AA.
AC   Q07108;
DE   RecName: Full=Early activation antigen CD69;
DE   AltName: Full=Activation inducer molecule;
DE            Short=AIM;
DE   AltName: Full=BL-AC/P26;
DE   AltName: Full=C-type lectin domain family 2 member C;
DE   AltName: Full=EA1;
DE   AltName: Full=Early T-cell activation antigen p60;
DE   AltName: Full=GP32/28;
DE   AltName: Full=Leukocyte surface antigen Leu-23;
DE   AltName: Full=MLR-3;
DE   AltName: CD_antigen=CD69;
GN   Name=CD69; Synonyms=CLEC2C;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   CD6_HUMAN               Reviewed;         668 AA.
AC   P30203; A4KAD4; A4KAD5; Q9UMF2; Q9Y4K7; Q9Y4K8; Q9Y4K9; Q9Y4L0;
DE   RecName: Full=T-cell differentiation antigen CD6;
DE   AltName: Full=T12;
DE   AltName: Full=TP120;
DE   AltName: CD_antigen=CD6;
DE   Flags: Precursor;
GN   Name=CD6;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CD70_HUMAN              Reviewed;         193 AA.
AC   P32970; Q53XX4; Q96J57;
DE   RecName: Full=CD70 antigen;
DE   AltName: Full=CD27 ligand;
DE            Short=CD27-L;
DE   AltName: Full=Tumor necrosis factor ligand superfamily member 7;
DE   AltName: CD_antigen=CD70;
GN   Name=CD70; Synonyms=CD27L, CD27LG, TNFSF7;
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD72_HUMAN              Reviewed;         359 AA.
AC   P21854;
DE   RecName: Full=B-cell differentiation antigen CD72;
DE   AltName: Full=Lyb-2;
DE   AltName: CD_antigen=CD72;
GN   Name=CD72;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   CD79A_HUMAN             Reviewed;         226 AA.
AC   P11912; A0N775; Q53FB8;
DE   RecName: Full=B-cell antigen receptor complex-associated protein alpha chain;
DE   AltName: Full=Ig-alpha;
DE   AltName: Full=MB-1 membrane glycoprotein;
DE   AltName: Full=Membrane-bound immunoglobulin-associated protein;
DE   AltName: Full=Surface IgM-associated protein;
DE   AltName: CD_antigen=CD79a;
DE   Flags: Precursor;
GN   Name=CD79A; Synonyms=IGA, MB1;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0042113; P:B cell activation; ISS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042100; P:B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
//
ID   CD79B_HUMAN             Reviewed;         229 AA.
AC   P40259; Q53FS2; Q9BU06;
DE   RecName: Full=B-cell antigen receptor complex-associated protein beta chain;
DE   AltName: Full=B-cell-specific glycoprotein B29;
DE   AltName: Full=Ig-beta;
DE   AltName: Full=Immunoglobulin-associated B29 protein;
DE   AltName: CD_antigen=CD79b;
DE   Flags: Precursor;
GN   Name=CD79B; Synonyms=B29, IGB;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD7_HUMAN               Reviewed;         240 AA.
AC   P09564;
DE   RecName: Full=T-cell antigen CD7;
DE   AltName: Full=GP40;
DE   AltName: Full=T-cell leukemia antigen;
DE   AltName: Full=T-cell surface antigen Leu-9;
DE   AltName: Full=TP41;
DE   AltName: CD_antigen=CD7;
DE   Flags: Precursor;
GN   Name=CD7;
DR   GO; GO:0004872; F:receptor activity; TAS:UniProtKB.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
//
ID   CD80_HUMAN              Reviewed;         288 AA.
AC   P33681; Q5DTA9; Q5DTB0;
DE   RecName: Full=T-lymphocyte activation antigen CD80;
DE   AltName: Full=Activation B7-1 antigen;
DE   AltName: Full=BB1;
DE   AltName: Full=CTLA-4 counter-receptor B7.1;
DE            Short=B7;
DE   AltName: CD_antigen=CD80;
DE   Flags: Precursor;
GN   Name=CD80; Synonyms=CD28LG, CD28LG1, LAB7;
DR   GuidetoPHARMACOLOGY; 2744; -.
DR   GO; GO:0015026; F:coreceptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045425; P:positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0045627; P:positive regulation of T-helper 1 cell differentiation; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; IC:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CD81_HUMAN              Reviewed;         236 AA.
AC   P60033; P18582; Q5U0J6;
DE   RecName: Full=CD81 antigen;
DE   AltName: Full=26 kDa cell surface protein TAPA-1;
DE   AltName: Full=Target of the antiproliferative antibody 1;
DE   AltName: Full=Tetraspanin-28;
DE            Short=Tspan-28;
DE   AltName: CD_antigen=CD81;
GN   Name=CD81; Synonyms=TAPA1, TSPAN28;
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; IDA:UniProtKB.
DR   GO; GO:0043128; P:positive regulation of 1-phosphatidylinositol 4-kinase activity; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
DR   GO; GO:0046813; P:receptor-mediated virion attachment to host cell; TAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
//
ID   CD83_HUMAN              Reviewed;         205 AA.
AC   Q01151; Q5THX9;
DE   RecName: Full=CD83 antigen;
DE            Short=hCD83;
DE   AltName: Full=B-cell activation protein;
DE   AltName: Full=Cell surface protein HB15;
DE   AltName: CD_antigen=CD83;
DE   Flags: Precursor;
GN   Name=CD83;
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0032713; P:negative regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CD82_HUMAN              Reviewed;         267 AA.
AC   P27701; D3DQN6; E9PC70; Q7Z2D4; Q7Z5N2;
DE   RecName: Full=CD82 antigen;
DE   AltName: Full=C33 antigen;
DE   AltName: Full=IA4;
DE   AltName: Full=Inducible membrane protein R2;
DE   AltName: Full=Metastasis suppressor Kangai-1;
DE   AltName: Full=Suppressor of tumorigenicity 6 protein;
DE   AltName: Full=Tetraspanin-27;
DE            Short=Tspan-27;
DE   AltName: CD_antigen=CD82;
GN   Name=CD82; Synonyms=KAI1, SAR2, ST6, TSPAN27;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CD86_HUMAN              Reviewed;         329 AA.
AC   P42081; A0N0P0; B7Z2F3; B7Z702; E7ETN5; E9PC27; Q13655; Q6FHB1;
AC   Q6GTS4; Q7M4L5;
DE   RecName: Full=T-lymphocyte activation antigen CD86;
DE   AltName: Full=Activation B7-2 antigen;
DE   AltName: Full=B70;
DE   AltName: Full=BU63;
DE   AltName: Full=CTLA-4 counter-receptor B7.2;
DE   AltName: Full=FUN-1;
DE   AltName: CD_antigen=CD86;
DE   Flags: Precursor;
GN   Name=CD86; Synonyms=CD28LG2;
DR   GuidetoPHARMACOLOGY; 2745; -.
DR   GO; GO:0015026; F:coreceptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0042113; P:B cell activation; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071248; P:cellular response to metal ion; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0002668; P:negative regulation of T cell anergy; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0045404; P:positive regulation of interleukin-4 biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0043017; P:positive regulation of lymphotoxin A biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell differentiation; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0034341; P:response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0001878; P:response to yeast; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; IC:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0002309; P:T cell proliferation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CD8A_HUMAN              Reviewed;         235 AA.
AC   P01732; B4DT80; D6W5M8; Q13970; Q4ZG17;
DE   RecName: Full=T-cell surface glycoprotein CD8 alpha chain;
DE   AltName: Full=T-lymphocyte differentiation antigen T8/Leu-2;
DE   AltName: CD_antigen=CD8a;
DE   Flags: Precursor;
GN   Name=CD8A; Synonyms=MAL;
DR   GO; GO:0015026; F:coreceptor activity; NAS:UniProtKB.
DR   GO; GO:0042288; F:MHC class I protein binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; NAS:UniProtKB.
DR   GO; GO:0045065; P:cytotoxic T cell differentiation; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0002456; P:T cell mediated immunity; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
//
ID   CD8BL_HUMAN             Reviewed;         211 AA.
AC   A6NJW9;
DE   RecName: Full=Putative T-cell surface glycoprotein CD8 beta-2 chain;
DE   AltName: Full=CD8b pseudogene;
DE   Flags: Precursor;
GN   Name=CD8BP; Synonyms=CD8B2;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   CD8B_HUMAN              Reviewed;         210 AA.
AC   P10966; P14860; P14861; Q15980; Q496E0; Q496E1; Q496E2; Q9UDB4;
AC   Q9UDB5; Q9UDB6; Q9UDB7; Q9UDB8; Q9UDB9; Q9UDC0; Q9UQ55;
DE   RecName: Full=T-cell surface glycoprotein CD8 beta chain;
DE   AltName: CD_antigen=CD8b;
DE   Flags: Precursor;
GN   Name=CD8B; Synonyms=CD8B1;
DR   GO; GO:0015026; F:coreceptor activity; NAS:UniProtKB.
DR   GO; GO:0042288; F:MHC class I protein binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CD97_HUMAN              Reviewed;         835 AA.
AC   P48960; A8K7Z4; B2RBJ9; O00718; O76101; Q8NG72; Q8TBQ7;
DE   RecName: Full=CD97 antigen;
DE   AltName: Full=Leukocyte antigen CD97;
DE   AltName: CD_antigen=CD97;
DE   Contains:
DE     RecName: Full=CD97 antigen subunit alpha;
DE   Contains:
DE     RecName: Full=CD97 antigen subunit beta;
DE   Flags: Precursor;
GN   Name=CD97;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   CD99_HUMAN              Reviewed;         185 AA.
AC   P14209; A6NIW1; O00518; Q6ICV7;
DE   RecName: Full=CD99 antigen;
DE   AltName: Full=12E7;
DE   AltName: Full=E2 antigen;
DE   AltName: Full=Protein MIC2;
DE   AltName: Full=T-cell surface glycoprotein E2;
DE   AltName: CD_antigen=CD99;
DE   Flags: Precursor;
GN   Name=CD99; Synonyms=MIC2, MIC2X, MIC2Y;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CD9_HUMAN               Reviewed;         228 AA.
AC   P21926; D3DUQ9; Q5J7W6; Q96ES4;
DE   RecName: Full=CD9 antigen;
DE   AltName: Full=5H9 antigen;
DE   AltName: Full=Cell growth-inhibiting gene 2 protein;
DE   AltName: Full=Leukocyte antigen MIC3;
DE   AltName: Full=Motility-related protein;
DE            Short=MRP-1;
DE   AltName: Full=Tetraspanin-29;
DE            Short=Tspan-29;
DE   AltName: Full=p24;
DE   AltName: CD_antigen=CD9;
GN   Name=CD9; Synonyms=MIC3, TSPAN29; ORFNames=GIG2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; IDA:UniProtKB.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IDA:UniProtKB.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0030913; P:paranodal junction assembly; ISS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0009414; P:response to water deprivation; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   CDA7L_HUMAN             Reviewed;         454 AA.
AC   Q96GN5; A4D141; A6NF50; B3KTR5; B4DUT3; C9K0Y1; Q6PIL4; Q86YT0;
AC   Q8IXN5; Q96C70; Q9H9A2; Q9NPV2;
DE   RecName: Full=Cell division cycle-associated 7-like protein;
DE   AltName: Full=Protein JPO2;
DE   AltName: Full=Transcription factor RAM2;
GN   Name=CDCA7L; Synonyms=HR1, JPO2, R1;
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CDAC1_HUMAN             Reviewed;         514 AA.
AC   Q9BWV3; Q49A08; Q4G119; Q5TAW9; Q7Z764; Q9NT36;
DE   RecName: Full=Cytidine and dCMP deaminase domain-containing protein 1;
DE   AltName: Full=Testis development protein NYD-SP15;
GN   Name=CDADC1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CDAN1_HUMAN             Reviewed;        1227 AA.
AC   Q8IWY9; Q6NYD0; Q7Z7L5; Q969N3;
DE   RecName: Full=Codanin-1;
GN   Name=CDAN1; ORFNames=UNQ664/PRO1295;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031497; P:chromatin assembly; IMP:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.
//
ID   CDC16_HUMAN             Reviewed;         620 AA.
AC   Q13042; A2A365; Q5T8C8; Q96AE6; Q9Y564;
DE   RecName: Full=Cell division cycle protein 16 homolog;
DE   AltName: Full=Anaphase-promoting complex subunit 6;
DE            Short=APC6;
DE   AltName: Full=CDC16 homolog;
DE            Short=CDC16Hs;
DE   AltName: Full=Cyclosome subunit 6;
GN   Name=CDC16; Synonyms=ANAPC6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   CDC20_HUMAN             Reviewed;         499 AA.
AC   Q12834; B2R6Z6; D3DPJ1; Q5JUY4; Q9BW56; Q9UQI9;
DE   RecName: Full=Cell division cycle protein 20 homolog;
DE   AltName: Full=p55CDC;
GN   Name=CDC20;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0050773; P:regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:0040020; P:regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   CDC23_HUMAN             Reviewed;         597 AA.
AC   Q9UJX2; A8K6E5; B4E3A2; B7WP05; D3DQB7; O75433; Q53FN2; Q9BS73;
DE   RecName: Full=Cell division cycle protein 23 homolog;
DE   AltName: Full=Anaphase-promoting complex subunit 8;
DE            Short=APC8;
DE   AltName: Full=Cyclosome subunit 8;
GN   Name=CDC23; Synonyms=ANAPC8;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; TAS:UniProtKB.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000080; P:mitotic G1 phase; IDA:UniProtKB.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IDA:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0007096; P:regulation of exit from mitosis; TAS:ProtInc.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   CDC26_HUMAN             Reviewed;          85 AA.
AC   Q8NHZ8;
DE   RecName: Full=Anaphase-promoting complex subunit CDC26;
DE   AltName: Full=Anaphase-promoting complex subunit 12;
DE            Short=APC12;
DE   AltName: Full=Cell division cycle protein 26 homolog;
GN   Name=CDC26; Synonyms=ANAPC12, C9orf17;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   CDC27_HUMAN             Reviewed;         824 AA.
AC   P30260; G3V1C4; Q16349; Q96F35;
DE   RecName: Full=Cell division cycle protein 27 homolog;
DE   AltName: Full=Anaphase-promoting complex subunit 3;
DE            Short=APC3;
DE   AltName: Full=CDC27 homolog;
DE            Short=CDC27Hs;
DE   AltName: Full=H-NUC;
GN   Name=CDC27; Synonyms=ANAPC3, D0S1430E, D17S978E;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IMP:MGI.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   CDC37_HUMAN             Reviewed;         378 AA.
AC   Q16543; Q53YA2;
DE   RecName: Full=Hsp90 co-chaperone Cdc37;
DE   AltName: Full=Hsp90 chaperone protein kinase-targeting subunit;
DE   AltName: Full=p50Cdc37;
DE   Contains:
DE     RecName: Full=Hsp90 co-chaperone Cdc37, N-terminally processed;
GN   Name=CDC37; Synonyms=CDC37A;
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006605; P:protein targeting; TAS:ProtInc.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; IMP:MGI.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; IMP:MGI.
//
ID   CDC42_HUMAN             Reviewed;         191 AA.
AC   P60953; P21181; P25763; Q7L8R5; Q9UDI2;
DE   RecName: Full=Cell division control protein 42 homolog;
DE   AltName: Full=G25K GTP-binding protein;
DE   Flags: Precursor;
GN   Name=CDC42;
DR   GO; GO:0034191; F:apolipoprotein A-I receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IDA:BHF-UCL.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0090135; P:actin filament branching; IEA:Ensembl.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0034332; P:adherens junction organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0003161; P:cardiac conduction system development; IEA:Ensembl.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0060684; P:epithelial-mesenchymal cell signaling; IEA:Ensembl.
DR   GO; GO:0051683; P:establishment of Golgi localization; ISS:BHF-UCL.
DR   GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IEA:Ensembl.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0046847; P:filopodium assembly; IEA:Ensembl.
DR   GO; GO:0007030; P:Golgi organization; ISS:BHF-UCL.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0060789; P:hair follicle placode formation; IEA:Ensembl.
DR   GO; GO:0060047; P:heart contraction; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031424; P:keratinization; IEA:Ensembl.
DR   GO; GO:0003334; P:keratinocyte development; IEA:Ensembl.
DR   GO; GO:0030225; P:macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IPI:UniProtKB.
DR   GO; GO:0048664; P:neuron fate determination; IEA:Ensembl.
DR   GO; GO:0007097; P:nuclear migration; IEA:Ensembl.
DR   GO; GO:0072384; P:organelle transport along microtubule; ISS:BHF-UCL.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0071338; P:positive regulation of hair follicle cell proliferation; IEA:Ensembl.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0048554; P:positive regulation of metalloenzyme activity; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IDA:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0051835; P:positive regulation of synapse structural plasticity; IEA:Ensembl.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0060661; P:submandibular salivary gland formation; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   CDC45_HUMAN             Reviewed;         566 AA.
AC   O75419; B4DDB4; B4DDU3; E9PDH7; O60856; Q20WK8; Q6UW54; Q9UP68;
DE   RecName: Full=Cell division control protein 45 homolog;
DE   AltName: Full=PORC-PI-1;
GN   Name=CDC45; Synonyms=CDC45L, CDC45L2; ORFNames=UNQ374/PRO710;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000076; P:DNA replication checkpoint; TAS:ProtInc.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
//
ID   CDC5L_HUMAN             Reviewed;         802 AA.
AC   Q99459; Q76N46; Q99974;
DE   RecName: Full=Cell division cycle 5-like protein;
DE            Short=Cdc5-like protein;
DE   AltName: Full=Pombe cdc5-related protein;
GN   Name=CDC5L; Synonyms=KIAA0432, PCDC5RP;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071987; F:WD40-repeat domain binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CDC6_HUMAN              Reviewed;         560 AA.
AC   Q99741; Q8TB30;
DE   RecName: Full=Cell division control protein 6 homolog;
DE   AltName: Full=CDC6-related protein;
DE   AltName: Full=Cdc18-related protein;
DE            Short=HsCdc18;
DE   AltName: Full=p62(cdc6);
DE            Short=HsCDC6;
GN   Name=CDC6; Synonyms=CDC18L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000076; P:DNA replication checkpoint; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0008156; P:negative regulation of DNA replication; TAS:ProtInc.
DR   GO; GO:0051984; P:positive regulation of chromosome segregation; IDA:BHF-UCL.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:BHF-UCL.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
//
ID   CDC73_HUMAN             Reviewed;         531 AA.
AC   Q6P1J9; A6NLZ8; B2RBR2; Q6PK51; Q96A07; Q9H245; Q9H5L7;
DE   RecName: Full=Parafibromin;
DE   AltName: Full=Cell division cycle protein 73 homolog;
DE   AltName: Full=Hyperparathyroidism 2 protein;
GN   Name=CDC73; Synonyms=C1orf28, HRPT2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IMP:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0031442; P:positive regulation of mRNA 3'-end processing; IMP:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IMP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CDC7_HUMAN              Reviewed;         574 AA.
AC   O00311; D3DT31; O00558; Q5T5U5;
DE   RecName: Full=Cell division cycle 7-related protein kinase;
DE            Short=CDC7-related kinase;
DE            Short=HsCdc7;
DE            Short=huCdc7;
DE            EC=2.7.11.1;
GN   Name=CDC7; Synonyms=CDC7L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IMP:UniProt.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044770; P:cell cycle phase transition; IMP:BHF-UCL.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:HGNC.
//
ID   CDCA3_HUMAN             Reviewed;         268 AA.
AC   Q99618; A8K5V6; D3DUS6;
DE   RecName: Full=Cell division cycle-associated protein 3;
DE   AltName: Full=Gene-rich cluster protein C8;
DE   AltName: Full=Trigger of mitotic entry protein 1;
DE            Short=TOME-1;
GN   Name=CDCA3; Synonyms=C8, GRCC8, TOME1;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   CDCA2_HUMAN             Reviewed;        1023 AA.
AC   Q69YH5; Q3SX74; Q4G0W0; Q5RKN0; Q69YI4; Q6P464; Q8N7C1;
DE   RecName: Full=Cell division cycle-associated protein 2;
DE   AltName: Full=Recruits PP1 onto mitotic chromatin at anaphase protein;
DE            Short=Repo-Man;
GN   Name=CDCA2;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   CDCA4_HUMAN             Reviewed;         241 AA.
AC   Q9BXL8; Q8TB18; Q9NWK7;
DE   RecName: Full=Cell division cycle-associated protein 4;
DE   AltName: Full=Hematopoietic progenitor protein;
GN   Name=CDCA4; Synonyms=HEPP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CDCA5_HUMAN             Reviewed;         252 AA.
AC   Q96FF9; A8K625;
DE   RecName: Full=Sororin;
DE   AltName: Full=Cell division cycle-associated protein 5;
DE   AltName: Full=p35;
GN   Name=CDCA5;
DR   GO; GO:0003682; F:chromatin binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IMP:UniProtKB.
DR   GO; GO:0051329; P:mitotic interphase; ISS:UniProtKB.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0071922; P:regulation of cohesin localization to chromatin; IMP:UniProtKB.
//
ID   CDCA7_HUMAN             Reviewed;         371 AA.
AC   Q9BWT1; B4DLP8; B4DV66; Q53EW5; Q580W9; Q658K4; Q658N4; Q8NBY9;
AC   Q96BV8; Q96SP5;
DE   RecName: Full=Cell division cycle-associated protein 7;
DE   AltName: Full=Protein JPO1;
GN   Name=CDCA7; Synonyms=JPO1;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CDCP1_HUMAN             Reviewed;         836 AA.
AC   Q9H5V8; Q49UB4; Q6NT71; Q6U9Y2; Q8WU91; Q96QU7; Q9H676; Q9H8C2;
DE   RecName: Full=CUB domain-containing protein 1;
DE   AltName: Full=Membrane glycoprotein gp140;
DE   AltName: Full=Subtractive immunization M plus HEp3-associated 135 kDa protein;
DE            Short=SIMA135;
DE   AltName: Full=Transmembrane and associated with src kinases;
DE   AltName: CD_antigen=CD318;
DE   Flags: Precursor;
GN   Name=CDCP1; Synonyms=TRASK; ORFNames=UNQ2486/PRO5773;
//
ID   CDCP2_HUMAN             Reviewed;         449 AA.
AC   Q5VXM1; Q6ZWJ3;
DE   RecName: Full=CUB domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=CDCP2;
//
ID   CDD_HUMAN               Reviewed;         146 AA.
AC   P32320;
DE   RecName: Full=Cytidine deaminase;
DE            EC=3.5.4.5;
DE   AltName: Full=Cytidine aminohydrolase;
GN   Name=CDA; Synonyms=CDD;
DR   GO; GO:0004126; F:cytidine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0001882; F:nucleoside binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0009972; P:cytidine deamination; IDA:UniProtKB.
DR   GO; GO:0019858; P:cytosine metabolic process; TAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045980; P:negative regulation of nucleotide metabolic process; IDA:UniProtKB.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0008655; P:pyrimidine-containing compound salvage; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CDHR1_HUMAN             Reviewed;         859 AA.
AC   Q96JP9; Q69YZ8; Q8IXY5;
DE   RecName: Full=Cadherin-related family member 1;
DE   AltName: Full=Photoreceptor cadherin;
DE            Short=prCAD;
DE   AltName: Full=Protocadherin-21;
DE   Flags: Precursor;
GN   Name=CDHR1; Synonyms=KIAA1775, PCDH21, PRCAD;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
//
ID   CDHR2_HUMAN             Reviewed;        1310 AA.
AC   Q9BYE9; A6NC80; Q9NXP8;
DE   RecName: Full=Cadherin-related family member 2;
DE   AltName: Full=Protocadherin LKC;
DE            Short=PC-LKC;
DE   AltName: Full=Protocadherin-24;
DE   Flags: Precursor;
GN   Name=CDHR2; Synonyms=PCDH24, PCLKC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
//
ID   CDHR4_HUMAN             Reviewed;         788 AA.
AC   A6H8M9; Q6UXT0;
DE   RecName: Full=Cadherin-related family member 4;
DE   AltName: Full=Cadherin-like protein 29;
DE   Flags: Precursor;
GN   Name=CDHR4; Synonyms=CDH29; ORFNames=UNQ9392/PRO34300;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CDHR5_HUMAN             Reviewed;         845 AA.
AC   Q9HBB8; C9J7X1; Q9H746; Q9HAU3; Q9HBB5; Q9HBB6; Q9HBB7; Q9NX86;
AC   Q9NXI9;
DE   RecName: Full=Cadherin-related family member 5;
DE   AltName: Full=Mu-protocadherin;
DE   AltName: Full=Mucin and cadherin-like protein;
DE   Flags: Precursor;
GN   Name=CDHR5; Synonyms=MUCDHL, MUPCDH; ORFNames=UNQ2781/PRO7168;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CDHR3_HUMAN             Reviewed;         885 AA.
AC   Q6ZTQ4; Q8TCI7;
DE   RecName: Full=Cadherin-related family member 3;
DE   AltName: Full=Cadherin-like protein 28;
DE   Flags: Precursor;
GN   Name=CDHR3; Synonyms=CDH28;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CDIP1_HUMAN             Reviewed;         208 AA.
AC   Q9H305; A8K7M1; B4DFU1; B4DY75; D3DUD6; Q96ID8; Q9H0Q4; Q9P112;
DE   RecName: Full=Cell death-inducing p53-target protein 1;
DE   AltName: Full=Cell death involved p53-target;
DE   AltName: Full=Cell death-inducing protein;
DE   AltName: Full=LITAF-like protein;
DE   AltName: Full=Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein;
DE   AltName: Full=Transmembrane protein I1;
GN   Name=CDIP1; Synonyms=C16orf5, CDIP, LITAFL;
DR   GO; GO:0006915; P:apoptotic process; IGI:MGI.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:MGI.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IGI:MGI.
//
ID   CDIPT_HUMAN             Reviewed;         213 AA.
AC   O14735; B4DUV0; H3BTV1; Q6FGU1; Q6ZN70;
DE   RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase;
DE            EC=2.7.8.11;
DE   AltName: Full=Phosphatidylinositol synthase;
DE            Short=PI synthase;
DE            Short=PtdIns synthase;
GN   Name=CDIPT; Synonyms=PIS, PIS1;
DR   GO; GO:0043178; F:alcohol binding; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0003881; F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0019992; F:diacylglycerol binding; IEA:Ensembl.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046341; P:CDP-diacylglycerol metabolic process; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CDK10_HUMAN             Reviewed;         360 AA.
AC   Q15131; A8MXU6; B7Z420; D3DX82; D3DX83; Q0VGZ7; Q15130; Q6PJC0;
DE   RecName: Full=Cyclin-dependent kinase 10;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 10;
DE   AltName: Full=Serine/threonine-protein kinase PISSLRE;
GN   Name=CDK10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
//
ID   CDK12_HUMAN             Reviewed;        1490 AA.
AC   Q9NYV4; A7E2B2; B4DYX4; B9EIQ6; O94978;
DE   RecName: Full=Cyclin-dependent kinase 12;
DE            EC=2.7.11.22;
DE            EC=2.7.11.23;
DE   AltName: Full=Cdc2-related kinase, arginine/serine-rich;
DE            Short=CrkRS;
DE   AltName: Full=Cell division cycle 2-related protein kinase 7;
DE            Short=CDC2-related protein kinase 7;
DE   AltName: Full=Cell division protein kinase 12;
DE            Short=hCDK12;
GN   Name=CDK12; Synonyms=CRK7, CRKRS, KIAA0904;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030332; F:cyclin binding; IPI:MGI.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:HGNC.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:HGNC.
DR   GO; GO:0043405; P:regulation of MAP kinase activity; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; ISS:UniProtKB.
//
ID   CDK13_HUMAN             Reviewed;        1512 AA.
AC   Q14004; Q53G78; Q6DKQ9; Q75MH4; Q75MH5; Q96JN4; Q9H4A0; Q9H4A1;
AC   Q9UDR4;
DE   RecName: Full=Cyclin-dependent kinase 13;
DE            EC=2.7.11.22;
DE            EC=2.7.11.23;
DE   AltName: Full=CDC2-related protein kinase 5;
DE   AltName: Full=Cell division cycle 2-like protein kinase 5;
DE   AltName: Full=Cell division protein kinase 13;
DE            Short=hCDK13;
DE   AltName: Full=Cholinesterase-related cell division controller;
GN   Name=CDK13; Synonyms=CDC2L, CDC2L5, CHED, KIAA1791;
DR   GuidetoPHARMACOLOGY; 1966; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030332; F:cyclin binding; IPI:MGI.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CDK14_HUMAN             Reviewed;         469 AA.
AC   O94921; A4D1E6; A6NK51; A8WFP6; B4DHG5; B4DNM2; Q75N06; Q75N22;
AC   Q8N764; Q9H3D7; Q9UDR0;
DE   RecName: Full=Cyclin-dependent kinase 14;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 14;
DE   AltName: Full=Serine/threonine-protein kinase PFTAIRE-1;
DE            Short=hPFTAIRE1;
GN   Name=CDK14; Synonyms=KIAA0834, PFTK1;
DR   GuidetoPHARMACOLOGY; 1967; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CDK15_HUMAN             Reviewed;         435 AA.
AC   Q96Q40; A8K8R9; B8ZZX0; C9J1N8; C9K003; F8W6H8; Q4ZG86; Q53TV1;
AC   Q6ZMR9; Q8IUP1;
DE   RecName: Full=Cyclin-dependent kinase 15;
DE            EC=2.7.11.22;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein;
DE   AltName: Full=Cell division protein kinase 15;
DE   AltName: Full=Serine/threonine-protein kinase ALS2CR7;
DE   AltName: Full=Serine/threonine-protein kinase PFTAIRE-2;
GN   Name=CDK15; Synonyms=ALS2CR7, PFTK2;
DR   GuidetoPHARMACOLOGY; 1968; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CDK16_HUMAN             Reviewed;         496 AA.
AC   Q00536; A8K280; B7Z7C8; J3KN74; J3KQP7;
DE   RecName: Full=Cyclin-dependent kinase 16;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 16;
DE   AltName: Full=PCTAIRE-motif protein kinase 1;
DE   AltName: Full=Serine/threonine-protein kinase PCTAIRE-1;
GN   Name=CDK16; Synonyms=PCTAIRE1, PCTK1;
DR   GuidetoPHARMACOLOGY; 1969; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; ISS:UniProtKB.
DR   GO; GO:0030252; P:growth hormone secretion; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   CDK18_HUMAN             Reviewed;         472 AA.
AC   Q07002; Q5VXQ2; Q6V3A2; Q6V3A3; Q96F90;
DE   RecName: Full=Cyclin-dependent kinase 18;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 18;
DE   AltName: Full=PCTAIRE-motif protein kinase 3;
DE   AltName: Full=Serine/threonine-protein kinase PCTAIRE-3;
GN   Name=CDK18; Synonyms=PCTAIRE3, PCTK3;
DR   GuidetoPHARMACOLOGY; 1971; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CDK17_HUMAN             Reviewed;         523 AA.
AC   Q00537; A8K1U6; B2RCQ2; Q8NEB8;
DE   RecName: Full=Cyclin-dependent kinase 17;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 17;
DE   AltName: Full=PCTAIRE-motif protein kinase 2;
DE   AltName: Full=Serine/threonine-protein kinase PCTAIRE-2;
GN   Name=CDK17; Synonyms=PCTAIRE2, PCTK2;
DR   GuidetoPHARMACOLOGY; 1970; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   CDK19_HUMAN             Reviewed;         502 AA.
AC   Q9BWU1; Q5JQZ7; Q5JR00; Q8TC78; Q9UPX2;
DE   RecName: Full=Cyclin-dependent kinase 19;
DE            EC=2.7.11.22;
DE   AltName: Full=CDC2-related protein kinase 6;
DE   AltName: Full=Cell division cycle 2-like protein kinase 6;
DE   AltName: Full=Cell division protein kinase 19;
DE   AltName: Full=Cyclin-dependent kinase 11;
DE   AltName: Full=Death-preventing kinase;
GN   Name=CDK19; Synonyms=CDC2L6, CDK11, KIAA1028;
DR   GuidetoPHARMACOLOGY; 1972; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
//
ID   CDK1_HUMAN              Reviewed;         297 AA.
AC   P06493; A8K7C4; C9J497; O60764;
DE   RecName: Full=Cyclin-dependent kinase 1;
DE            Short=CDK1;
DE            EC=2.7.11.22;
DE            EC=2.7.11.23;
DE   AltName: Full=Cell division control protein 2 homolog;
DE   AltName: Full=Cell division protein kinase 1;
DE   AltName: Full=p34 protein kinase;
GN   Name=CDK1; Synonyms=CDC2, CDC28A, CDKN1, P34CDC2;
DR   GuidetoPHARMACOLOGY; 1961; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035173; F:histone kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0007098; P:centrosome cycle; TAS:UniProtKB.
DR   GO; GO:0030261; P:chromosome condensation; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007344; P:pronuclear fusion; TAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0034501; P:protein localization to kinetochore; IDA:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0045995; P:regulation of embryonic development; TAS:UniProtKB.
DR   GO; GO:0014038; P:regulation of Schwann cell differentiation; TAS:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
//
ID   CDK20_HUMAN             Reviewed;         346 AA.
AC   Q8IZL9; A2A389; A2A390; B4DQX1; O95137; Q5EDC4; Q5VYW1; Q9BUF4;
DE   RecName: Full=Cyclin-dependent kinase 20;
DE            EC=2.7.11.22;
DE   AltName: Full=CDK-activating kinase p42;
DE            Short=CAK-kinase p42;
DE   AltName: Full=Cell cycle-related kinase;
DE   AltName: Full=Cell division protein kinase 20;
DE   AltName: Full=Cyclin-dependent protein kinase H;
DE   AltName: Full=Cyclin-kinase-activating kinase p42;
GN   Name=CDK20; Synonyms=CCRK, CDCH;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   CDK2_HUMAN              Reviewed;         298 AA.
AC   P24941; A8K7C6; O75100;
DE   RecName: Full=Cyclin-dependent kinase 2;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 2;
DE   AltName: Full=p33 protein kinase;
GN   Name=CDK2; Synonyms=CDKN2;
DR   GuidetoPHARMACOLOGY; 1973; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030332; F:cyclin binding; IDA:UniProtKB.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071732; P:cellular response to nitric oxide; TAS:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; TAS:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; TAS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; NAS:UniProtKB.
DR   GO; GO:0016572; P:histone phosphorylation; IDA:GOC.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; TAS:UniProtKB.
DR   GO; GO:0000085; P:mitotic G2 phase; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0032298; P:positive regulation of DNA-dependent DNA replication initiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.
DR   GO; GO:0060968; P:regulation of gene silencing; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   CDK3_HUMAN              Reviewed;         305 AA.
AC   Q00526;
DE   RecName: Full=Cyclin-dependent kinase 3;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 3;
GN   Name=CDK3; Synonyms=CDKN3;
DR   GuidetoPHARMACOLOGY; 1975; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0045023; P:G0 to G1 transition; TAS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   CDK4_HUMAN              Reviewed;         303 AA.
AC   P11802; O00576; Q6FG61;
DE   RecName: Full=Cyclin-dependent kinase 4;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 4;
DE   AltName: Full=PSK-J3;
GN   Name=CDK4;
DR   GuidetoPHARMACOLOGY; 1976; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045793; P:positive regulation of cell size; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IGI:UniProtKB.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
//
ID   CDK5_HUMAN              Reviewed;         292 AA.
AC   Q00535; A1XKG3;
DE   RecName: Full=Cyclin-dependent kinase 5;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 5;
DE   AltName: Full=Serine/threonine-protein kinase PSSALRE;
DE   AltName: Full=Tau protein kinase II catalytic subunit;
DE            Short=TPKII catalytic subunit;
GN   Name=CDK5; Synonyms=CDKN5;
DR   GuidetoPHARMACOLOGY; 1977; -.
DR   GO; GO:0030549; F:acetylcholine receptor activator activity; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0005176; F:ErbB-2 class receptor binding; ISS:UniProtKB.
DR   GO; GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.
DR   GO; GO:0016301; F:kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0048675; P:axon extension; TAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IEA:Ensembl.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0021697; P:cerebellar cortex formation; IEA:Ensembl.
DR   GO; GO:0022038; P:corpus callosum development; IEA:Ensembl.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0046826; P:negative regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0031914; P:negative regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:DFLAT.
DR   GO; GO:0051402; P:neuron apoptotic process; TAS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; TAS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0016310; P:phosphorylation; IDA:DFLAT.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; TAS:UniProtKB.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:2000273; P:positive regulation of receptor activity; ISS:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0035418; P:protein localization to synapse; IEA:Ensembl.
DR   GO; GO:0032801; P:receptor catabolic process; IEA:Ensembl.
DR   GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
DR   GO; GO:0045055; P:regulated secretory pathway; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0014044; P:Schwann cell development; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0033136; P:serine phosphorylation of STAT3 protein; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; TAS:UniProtKB.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   CDK6_HUMAN              Reviewed;         326 AA.
AC   Q00534;
DE   RecName: Full=Cyclin-dependent kinase 6;
DE            EC=2.7.11.22;
DE   AltName: Full=Cell division protein kinase 6;
DE   AltName: Full=Serine/threonine-protein kinase PLSTIRE;
GN   Name=CDK6; Synonyms=CDKN6;
DR   GuidetoPHARMACOLOGY; 1978; -.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0030332; F:cyclin binding; IPI:BHF-UCL.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0014002; P:astrocyte development; ISS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0043697; P:cell dedifferentiation; IMP:BHF-UCL.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0021542; P:dentate gyrus development; ISS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0048699; P:generation of neurons; ISS:UniProtKB.
DR   GO; GO:0042063; P:gliogenesis; IMP:BHF-UCL.
DR   GO; GO:0021670; P:lateral ventricle development; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:2000145; P:regulation of cell motility; ISS:UniProtKB.
DR   GO; GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0003323; P:type B pancreatic cell development; IDA:UniProtKB.
//
ID   CDK7_HUMAN              Reviewed;         346 AA.
AC   P50613; Q9BS60; Q9UE19;
DE   RecName: Full=Cyclin-dependent kinase 7;
DE            EC=2.7.11.22;
DE            EC=2.7.11.23;
DE   AltName: Full=39 kDa protein kinase;
DE            Short=p39 Mo15;
DE   AltName: Full=CDK-activating kinase 1;
DE   AltName: Full=Cell division protein kinase 7;
DE   AltName: Full=Serine/threonine-protein kinase 1;
DE   AltName: Full=TFIIH basal transcription factor complex kinase subunit;
GN   Name=CDK7; Synonyms=CAK, CAK1, CDKN7, MO15, STK1;
DR   GuidetoPHARMACOLOGY; 1979; -.
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CDK8_HUMAN              Reviewed;         464 AA.
AC   P49336; Q5VUF3; Q6ISB5;
DE   RecName: Full=Cyclin-dependent kinase 8;
DE            EC=2.7.11.22;
DE            EC=2.7.11.23;
DE   AltName: Full=Cell division protein kinase 8;
DE   AltName: Full=Mediator complex subunit CDK8;
DE   AltName: Full=Mediator of RNA polymerase II transcription subunit CDK8;
DE   AltName: Full=Protein kinase K35;
GN   Name=CDK8;
DR   GuidetoPHARMACOLOGY; 1980; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   CDK9_HUMAN              Reviewed;         372 AA.
AC   P50750; Q5JU24; Q5JU25; Q5U006; Q96TF1;
DE   RecName: Full=Cyclin-dependent kinase 9;
DE            EC=2.7.11.22;
DE            EC=2.7.11.23;
DE   AltName: Full=C-2K;
DE   AltName: Full=Cell division cycle 2-like protein kinase 4;
DE   AltName: Full=Cell division protein kinase 9;
DE   AltName: Full=Serine/threonine-protein kinase PITALRE;
DE   AltName: Full=Tat-associated kinase complex catalytic subunit;
GN   Name=CDK9; Synonyms=CDC2L4, TAK;
DR   GuidetoPHARMACOLOGY; 1981; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB.
DR   GO; GO:0017069; F:snRNA binding; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:MGI.
DR   GO; GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0031056; P:regulation of histone modification; IDA:UniProtKB.
DR   GO; GO:0043111; P:replication fork arrest; IDA:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CDKA1_HUMAN             Reviewed;         115 AA.
AC   O14519; F5GYA4;
DE   RecName: Full=Cyclin-dependent kinase 2-associated protein 1;
DE            Short=CDK2-associated protein 1;
DE   AltName: Full=Deleted in oral cancer 1;
DE            Short=DOC-1;
DE   AltName: Full=Putative oral cancer suppressor;
GN   Name=CDK2AP1; Synonyms=CDKAP1, DOC1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0000084; P:mitotic S phase; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   CDKA2_HUMAN             Reviewed;         126 AA.
AC   O75956;
DE   RecName: Full=Cyclin-dependent kinase 2-associated protein 2;
DE            Short=CDK2-associated protein 2;
DE   AltName: Full=DOC-1-related protein;
DE            Short=DOC-1R;
GN   Name=CDK2AP2; Synonyms=DOC1R;
//
ID   CDKAL_HUMAN             Reviewed;         579 AA.
AC   Q5VV42; A8K6S0; Q6P385; Q6ZR27; Q9NXB3;
DE   RecName: Full=Threonylcarbamoyladenosine tRNA methylthiotransferase;
DE            EC=2.-.-.-;
DE   AltName: Full=CDK5 regulatory subunit-associated protein 1-like 1;
DE   AltName: Full=tRNA-t(6)A37 methylthiotransferase;
GN   Name=CDKAL1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035598; F:N6-threonylcarbomyladenosine methylthiotransferase activity; IEA:Ensembl.
DR   GO; GO:1990145; P:maintenance of translational fidelity; IEA:Ensembl.
//
ID   CDKL1_HUMAN             Reviewed;         357 AA.
AC   Q00532; Q2M3A4; Q6QUA0; Q8WXQ5;
DE   RecName: Full=Cyclin-dependent kinase-like 1;
DE            EC=2.7.11.22;
DE   AltName: Full=Protein kinase p42 KKIALRE;
DE   AltName: Full=Serine/threonine-protein kinase KKIALRE;
GN   Name=CDKL1;
DR   GuidetoPHARMACOLOGY; 1982; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   CDKL2_HUMAN             Reviewed;         493 AA.
AC   Q92772; B2R695;
DE   RecName: Full=Cyclin-dependent kinase-like 2;
DE            EC=2.7.11.22;
DE   AltName: Full=Protein kinase p56 KKIAMRE;
DE   AltName: Full=Serine/threonine-protein kinase KKIAMRE;
GN   Name=CDKL2;
DR   GuidetoPHARMACOLOGY; 1983; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0007548; P:sex differentiation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CDKL3_HUMAN             Reviewed;         592 AA.
AC   Q8IVW4; D3DQA0; D3DQA1; Q9P114;
DE   RecName: Full=Cyclin-dependent kinase-like 3;
DE            EC=2.7.11.22;
DE   AltName: Full=Serine/threonine-protein kinase NKIAMRE;
GN   Name=CDKL3; Synonyms=NKIAMRE;
DR   GuidetoPHARMACOLOGY; 1984; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
//
ID   CDKL4_HUMAN             Reviewed;         315 AA.
AC   Q5MAI5;
DE   RecName: Full=Cyclin-dependent kinase-like 4;
DE            EC=2.7.11.22;
GN   Name=CDKL4;
DR   GuidetoPHARMACOLOGY; 1985; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
//
ID   CDKL5_HUMAN             Reviewed;        1030 AA.
AC   O76039; G9B9X4; Q14198; Q5H985; Q8IYC7; Q9UJL6;
DE   RecName: Full=Cyclin-dependent kinase-like 5;
DE            EC=2.7.11.22;
DE   AltName: Full=Serine/threonine-protein kinase 9;
GN   Name=CDKL5; Synonyms=STK9;
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016301; F:kinase activity; IDA:MGI.
DR   GO; GO:0004672; F:protein kinase activity; IDA:HGNC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0048365; F:Rac GTPase binding; ISS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; ISS:BHF-UCL.
DR   GO; GO:0045773; P:positive regulation of axon extension; ISS:BHF-UCL.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:HGNC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0050773; P:regulation of dendrite development; ISS:BHF-UCL.
//
ID   CDKN3_HUMAN             Reviewed;         212 AA.
AC   Q16667; Q53ZU6; Q5U0M4; Q6P1N8; Q99585; Q9BPW7; Q9BY36; Q9C042;
AC   Q9C046; Q9C047; Q9C049; Q9C051; Q9C053;
DE   RecName: Full=Cyclin-dependent kinase inhibitor 3;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=CDK2-associated dual-specificity phosphatase;
DE   AltName: Full=Cyclin-dependent kinase interactor 1;
DE   AltName: Full=Cyclin-dependent kinase-interacting protein 2;
DE   AltName: Full=Kinase-associated phosphatase;
GN   Name=CDKN3; Synonyms=CDI1, CIP2, KAP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:MGI.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:MGI.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:MGI.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
//
ID   CDN1A_HUMAN             Reviewed;         164 AA.
AC   P38936; Q14010; Q6FI05; Q9BUT4;
DE   RecName: Full=Cyclin-dependent kinase inhibitor 1;
DE   AltName: Full=CDK-interacting protein 1;
DE   AltName: Full=Melanoma differentiation-associated protein 6;
DE            Short=MDA-6;
DE   AltName: Full=p21;
GN   Name=CDKN1A; Synonyms=CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1;
DR   GO; GO:0019912; F:cyclin-dependent protein kinase activating kinase activity; IDA:UniProtKB.
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; TAS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:BHF-UCL.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IMP:BHF-UCL.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.
DR   GO; GO:0090398; P:cellular senescence; IMP:BHF-UCL.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:2000278; P:regulation of DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0033158; P:regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
DR   GO; GO:0090400; P:stress-induced premature senescence; TAS:BHF-UCL.
//
ID   CDN1B_HUMAN             Reviewed;         198 AA.
AC   P46527; Q16307; Q5U0H2; Q9BUS6;
DE   RecName: Full=Cyclin-dependent kinase inhibitor 1B;
DE   AltName: Full=Cyclin-dependent kinase inhibitor p27;
DE   AltName: Full=p27Kip1;
GN   Name=CDKN1B; Synonyms=KIP1;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0005072; F:transforming growth factor beta receptor, cytoplasmic mediator activity; TAS:ProtInc.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048102; P:autophagic cell death; IDA:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:HGNC.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IDA:MGI.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051271; P:negative regulation of cellular component movement; IEA:Ensembl.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IDA:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.
DR   GO; GO:0006813; P:potassium ion transport; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   CDN1C_HUMAN             Reviewed;         316 AA.
AC   P49918;
DE   RecName: Full=Cyclin-dependent kinase inhibitor 1C;
DE   AltName: Full=Cyclin-dependent kinase inhibitor p57;
DE   AltName: Full=p57Kip2;
GN   Name=CDKN1C; Synonyms=KIP2;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0000080; P:mitotic G1 phase; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IDA:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; TAS:GOC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IGI:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
//
ID   CDN2B_HUMAN             Reviewed;         138 AA.
AC   P42772; O15125; Q6FI09;
DE   RecName: Full=Cyclin-dependent kinase 4 inhibitor B;
DE   AltName: Full=Multiple tumor suppressor 2;
DE            Short=MTS-2;
DE   AltName: Full=p14-INK4b;
DE   AltName: Full=p15-INK4b;
DE            Short=p15INK4B;
GN   Name=CDKN2B; Synonyms=MTS2;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IMP:BHF-UCL.
DR   GO; GO:0031670; P:cellular response to nutrient; IMP:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030219; P:megakaryocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:GOC.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   CDN2C_HUMAN             Reviewed;         168 AA.
AC   P42773; Q8TB83;
DE   RecName: Full=Cyclin-dependent kinase 4 inhibitor C;
DE   AltName: Full=Cyclin-dependent kinase 6 inhibitor;
DE   AltName: Full=p18-INK4c;
DE   AltName: Full=p18-INK6;
GN   Name=CDKN2C; Synonyms=CDKN6;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:GOC.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
//
ID   CDN2D_HUMAN             Reviewed;         166 AA.
AC   P55273; Q13102; Q6FGE9;
DE   RecName: Full=Cyclin-dependent kinase 4 inhibitor D;
DE   AltName: Full=p19-INK4d;
GN   Name=CDKN2D;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0048102; P:autophagic cell death; IMP:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IMP:BHF-UCL.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:GOC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0009411; P:response to UV; IMP:BHF-UCL.
DR   GO; GO:0033280; P:response to vitamin D; IMP:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   CDNF_HUMAN              Reviewed;         187 AA.
AC   Q49AH0; A2RUU0; B4DVW3;
DE   RecName: Full=Cerebral dopamine neurotrophic factor;
DE   AltName: Full=ARMET-like protein 1;
DE   AltName: Full=Conserved dopamine neurotrophic factor;
DE   Flags: Precursor;
GN   Name=CDNF; Synonyms=ARMETL1;
//
ID   CDO1_HUMAN              Reviewed;         200 AA.
AC   Q16878; B2RAK4; P78513; Q6FHZ8; Q8TB64;
DE   RecName: Full=Cysteine dioxygenase type 1;
DE            EC=1.13.11.20;
DE   AltName: Full=Cysteine dioxygenase type I;
DE            Short=CDO;
DE            Short=CDO-I;
GN   Name=CDO1;
DR   GO; GO:0017172; F:cysteine dioxygenase activity; ISS:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006534; P:cysteine metabolic process; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0019448; P:L-cysteine catabolic process; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000097; P:sulfur amino acid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0042412; P:taurine biosynthetic process; TAS:UniProtKB.
//
ID   CDON_HUMAN              Reviewed;        1287 AA.
AC   Q4KMG0; O14631;
DE   RecName: Full=Cell adhesion molecule-related/down-regulated by oncogenes;
DE   Flags: Precursor;
GN   Name=CDON; Synonyms=CDO;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0010172; P:embryonic body morphogenesis; IEA:Ensembl.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IEA:Ensembl.
DR   GO; GO:0014816; P:satellite cell differentiation; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   CDPF1_HUMAN             Reviewed;         123 AA.
AC   Q6NVV7; A6NCA1; A9IU12; A9IU16; Q3ZCR8;
DE   RecName: Full=Cysteine-rich DPF motif domain-containing protein 1;
GN   Name=CDPF1; Synonyms=C22orf40;
//
ID   CDR2L_HUMAN             Reviewed;         465 AA.
AC   Q86X02; B4DFA7; Q15175;
DE   RecName: Full=Cerebellar degeneration-related protein 2-like;
DE   AltName: Full=Paraneoplastic 62 kDa antigen;
GN   Name=CDR2L; Synonyms=HUMPPA;
//
ID   CDR1_HUMAN              Reviewed;         262 AA.
AC   P51861; Q5JXH6;
DE   RecName: Full=Cerebellar degeneration-related antigen 1;
DE   AltName: Full=CDR34;
GN   Name=CDR1;
//
ID   CDR2_HUMAN              Reviewed;         454 AA.
AC   Q01850; A8K8A8; Q13977;
DE   RecName: Full=Cerebellar degeneration-related protein 2;
DE   AltName: Full=Major Yo paraneoplastic antigen;
DE   AltName: Full=Paraneoplastic cerebellar degeneration-associated antigen;
GN   Name=CDR2; Synonyms=PCD17;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CDRT1_HUMAN             Reviewed;         752 AA.
AC   O95170; O43848; O95611;
DE   RecName: Full=CMT1A duplicated region transcript 1 protein;
GN   Name=CDRT1; Synonyms=C17orf1, C17orf1A, HREP;
//
ID   CDRT4_HUMAN             Reviewed;         151 AA.
AC   Q8N9R6; A8MSL9; Q8IZ19;
DE   RecName: Full=CMT1A duplicated region transcript 4 protein;
GN   Name=CDRT4;
//
ID   CDRTF_HUMAN             Reviewed;         188 AA.
AC   Q96T59; B2RUU5;
DE   RecName: Full=CMT1A duplicated region transcript 15 protein;
GN   Name=CDRT15;
//
ID   CDS1_HUMAN              Reviewed;         461 AA.
AC   Q92903; B2RAL5; O00163;
DE   RecName: Full=Phosphatidate cytidylyltransferase 1;
DE            EC=2.7.7.41;
DE   AltName: Full=CDP-DAG synthase 1;
DE   AltName: Full=CDP-DG synthase 1;
DE   AltName: Full=CDP-diacylglycerol synthase 1;
DE            Short=CDS 1;
DE   AltName: Full=CDP-diglyceride pyrophosphorylase 1;
DE   AltName: Full=CDP-diglyceride synthase 1;
DE   AltName: Full=CTP:phosphatidate cytidylyltransferase 1;
GN   Name=CDS1; Synonyms=CDS;
DR   GO; GO:0004142; F:diacylglycerol cholinephosphotransferase activity; NAS:UniProtKB.
DR   GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006657; P:CDP-choline pathway; NAS:GOC.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007602; P:phototransduction; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CDS2_HUMAN              Reviewed;         445 AA.
AC   O95674; B2RDC6; D3DW04; Q5TDY2; Q5TDY3; Q5TDY4; Q5TDY5; Q9BYK5;
AC   Q9NTT2;
DE   RecName: Full=Phosphatidate cytidylyltransferase 2;
DE            EC=2.7.7.41;
DE   AltName: Full=CDP-DAG synthase 2;
DE   AltName: Full=CDP-DG synthase 2;
DE   AltName: Full=CDP-diacylglycerol synthase 2;
DE            Short=CDS 2;
DE   AltName: Full=CDP-diglyceride pyrophosphorylase 2;
DE   AltName: Full=CDP-diglyceride synthase 2;
DE   AltName: Full=CTP:phosphatidate cytidylyltransferase 2;
GN   Name=CDS2;
DR   GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CDSN_HUMAN              Reviewed;         529 AA.
AC   Q15517; B0S7V2; B0UYZ7; O43509; Q5SQ85; Q5STD2; Q7LA70; Q7LA71;
AC   Q86Z04; Q8IZU4; Q8IZU5; Q8IZU6; Q8N5P3; Q95IF9; Q9NP52; Q9NPE0;
AC   Q9NPG5; Q9NRH4; Q9NRH5; Q9NRH6; Q9NRH7; Q9NRH8; Q9UBH8; Q9UIN6;
AC   Q9UIN7; Q9UIN8; Q9UIN9; Q9UIP0;
DE   RecName: Full=Corneodesmosin;
DE   AltName: Full=S protein;
DE   Flags: Precursor;
GN   Name=CDSN;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:MGI.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0043589; P:skin morphogenesis; IMP:UniProtKB.
//
ID   CDT1_HUMAN              Reviewed;         546 AA.
AC   Q9H211; Q86XX9; Q96CJ5; Q96GK5; Q96H67; Q96HE6; Q9BWM0;
DE   RecName: Full=DNA replication factor Cdt1;
DE   AltName: Full=Double parked homolog;
DE            Short=DUP;
GN   Name=CDT1;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000076; P:DNA replication checkpoint; IDA:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IDA:UniProtKB.
DR   GO; GO:0033262; P:regulation of nuclear cell cycle DNA replication; IEA:Ensembl.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
//
ID   CDV3_HUMAN              Reviewed;         258 AA.
AC   Q9UKY7; B3KUC2; Q96IP9;
DE   RecName: Full=Protein CDV3 homolog;
GN   Name=CDV3; Synonyms=H41;
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
//
ID   CDX1_HUMAN              Reviewed;         265 AA.
AC   P47902; Q4VAU4; Q9NYK8;
DE   RecName: Full=Homeobox protein CDX-1;
DE   AltName: Full=Caudal-type homeobox protein 1;
GN   Name=CDX1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:NTNU_SB.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:NTNU_SB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:NTNU_SB.
//
ID   CDX2_HUMAN              Reviewed;         313 AA.
AC   Q99626; O00503; Q5VTU7; Q969L8; Q9UD92;
DE   RecName: Full=Homeobox protein CDX-2;
DE   AltName: Full=CDX-3;
DE   AltName: Full=Caudal-type homeobox protein 2;
GN   Name=CDX2; Synonyms=CDX3;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:NTNU_SB.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   CDX4_HUMAN              Reviewed;         284 AA.
AC   O14627; A1A513; Q5JS20;
DE   RecName: Full=Homeobox protein CDX-4;
DE   AltName: Full=Caudal-type homeobox protein 4;
GN   Name=CDX4;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CDY1_HUMAN              Reviewed;         540 AA.
AC   Q9Y6F8; A2RUK1; O14600;
DE   RecName: Full=Testis-specific chromodomain protein Y 1;
DE            EC=2.3.1.48;
GN   Name=CDY1; Synonyms=CDY1A;
GN   and
GN   Name=CDY1B;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   CDY2_HUMAN              Reviewed;         541 AA.
AC   Q9Y6F7; A8K868;
DE   RecName: Full=Testis-specific chromodomain protein Y 2;
DE            EC=2.3.1.48;
GN   Name=CDY2A; Synonyms=CDY2;
GN   and
GN   Name=CDY2B;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   CDYL1_HUMAN             Reviewed;         598 AA.
AC   Q9Y232; A8K6D6; B4DLG4; Q0VDG7; Q32NC5; Q5VX99; Q6P7T5; Q9BWZ2;
AC   Q9Y424;
DE   RecName: Full=Chromodomain Y-like protein;
DE            Short=CDY-like;
DE            EC=2.3.1.48;
GN   Name=CDYL; Synonyms=CDYL1;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CDYL2_HUMAN             Reviewed;         506 AA.
AC   Q8N8U2; Q7Z5I8;
DE   RecName: Full=Chromodomain Y-like protein 2;
DE            Short=CDY-like 2;
GN   Name=CDYL2;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   CE017_HUMAN             Reviewed;         161 AA.
AC   Q8NAS9; Q2I376;
DE   RecName: Full=Uncharacterized protein C5orf17;
GN   Name=C5orf17;
//
ID   CE022_HUMAN             Reviewed;         442 AA.
AC   Q49AR2; Q8ND28; Q8WU61; Q9NUR1;
DE   RecName: Full=UPF0489 protein C5orf22;
GN   Name=C5orf22;
//
ID   CE024_HUMAN             Reviewed;         188 AA.
AC   Q7Z6I8; D3DQA7; Q86Y53; Q8N1T9;
DE   RecName: Full=UPF0461 protein C5orf24;
GN   Name=C5orf24;
//
ID   CE027_HUMAN             Reviewed;          96 AA.
AC   Q52M75; B2RBN1; Q86YS4;
DE   RecName: Full=Putative uncharacterized protein C5orf27;
DE   AltName: Full=Protein FIS;
GN   Name=C5orf27;
//
ID   CE028_HUMAN             Reviewed;         215 AA.
AC   Q0VDI3; B2RDA6; Q9H6Z2;
DE   RecName: Full=Transmembrane protein C5orf28;
GN   Name=C5orf28;
//
ID   CE030_HUMAN             Reviewed;         206 AA.
AC   Q96GV9;
DE   RecName: Full=UNC119-binding protein C5orf30;
GN   Name=C5orf30;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   CE034_HUMAN             Reviewed;         638 AA.
AC   Q96MH7;
DE   RecName: Full=Uncharacterized protein C5orf34;
GN   Name=C5orf34;
//
ID   CE042_HUMAN             Reviewed;        3197 AA.
AC   Q9H799; A8MUB7; B7ZLV7; Q4G174; Q6DK46; Q8N8L4; Q9H5T1; Q9H8T9;
DE   RecName: Full=Uncharacterized protein C5orf42;
GN   Name=C5orf42;
//
ID   CE046_HUMAN             Reviewed;          87 AA.
AC   Q6UWT4; A8K038; Q8WU04;
DE   RecName: Full=Uncharacterized protein C5orf46;
DE   Flags: Precursor;
GN   Name=C5orf46; ORFNames=UNQ472/PRO839;
//
ID   CE049_HUMAN             Reviewed;         147 AA.
AC   A4QMS7;
DE   RecName: Full=Uncharacterized protein C5orf49;
GN   Name=C5orf49;
//
ID   CE051_HUMAN             Reviewed;         294 AA.
AC   A6NDU8; A2RRM9;
DE   RecName: Full=UPF0600 protein C5orf51;
GN   Name=C5orf51;
//
ID   CE055_HUMAN             Reviewed;         119 AA.
AC   Q8N2X6; Q96CR9;
DE   RecName: Full=Uncharacterized protein C5orf55;
DE   Flags: Precursor;
GN   Name=C5orf55;
//
ID   CE056_HUMAN             Reviewed;         126 AA.
AC   Q8N8D9; A1L3V9; A6NKA0;
DE   RecName: Full=Uncharacterized protein C5orf56;
GN   Name=C5orf56;
//
ID   CE045_HUMAN             Reviewed;         343 AA.
AC   Q6NTE8; B5MD09; E9PAK6; Q7Z3D8; Q9BUC1; Q9UN54;
DE   RecName: Full=UPF0544 protein C5orf45;
GN   Name=C5orf45;
//
ID   CE060_HUMAN             Reviewed;         353 AA.
AC   A6NFR6; A1L488; B7ZM52; B7ZM53;
DE   RecName: Full=Putative uncharacterized protein C5orf60;
GN   Name=C5orf60;
//
ID   CE058_HUMAN             Reviewed;         102 AA.
AC   C9J3I9;
DE   RecName: Full=Putative uncharacterized protein C5orf58;
GN   Name=C5orf58;
//
ID   CE052_HUMAN             Reviewed;         159 AA.
AC   A6NGY3;
DE   RecName: Full=Uncharacterized protein C5orf52;
GN   Name=C5orf52;
//
ID   CE064_HUMAN             Reviewed;         130 AA.
AC   Q2M2E5; Q2M2H1; Q8N1U8;
DE   RecName: Full=Uncharacterized protein C5orf64;
DE   Flags: Precursor;
GN   Name=C5orf64;
//
ID   CE066_HUMAN             Reviewed;         145 AA.
AC   Q9H5L9;
DE   RecName: Full=Putative uncharacterized protein C5orf66;
GN   Name=C5orf66;
//
ID   CE047_HUMAN             Reviewed;         176 AA.
AC   Q569G3; Q8IYU7;
DE   RecName: Full=Uncharacterized protein C5orf47;
GN   Name=C5orf47;
//
ID   CE104_HUMAN             Reviewed;         925 AA.
AC   O60308; Q5JSQ3; Q5SR24; Q5SR25; Q6PKF5; Q86W32; Q86X14;
DE   RecName: Full=Centrosomal protein of 104 kDa;
DE            Short=Cep104;
GN   Name=CEP104; Synonyms=KIAA0562;
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0016594; F:glycine binding; IEA:Ensembl.
DR   GO; GO:0016596; F:thienylcyclohexylpiperidine binding; IEA:Ensembl.
//
ID   CE112_HUMAN             Reviewed;         955 AA.
AC   Q8N8E3; Q6PIB5; Q8NCR4; Q8NFR4;
DE   RecName: Full=Centrosomal protein of 112 kDa;
DE            Short=Cep112;
DE   AltName: Full=Coiled-coil domain-containing protein 46;
GN   Name=CEP112; Synonyms=CCDC46;
DR   GO; GO:0097120; P:receptor localization to synapse; IEA:Ensembl.
//
ID   CE120_HUMAN             Reviewed;         986 AA.
AC   Q8N960; Q6AI52; Q6AW89; Q8IWB5; Q8N9Y0; Q8NDE8;
DE   RecName: Full=Centrosomal protein of 120 kDa;
DE            Short=Cep120;
DE   AltName: Full=Coiled-coil domain-containing protein 100;
GN   Name=CEP120; Synonyms=CCDC100;
DR   GO; GO:0030953; P:astral microtubule organization; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0022027; P:interkinetic nuclear migration; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
//
ID   CE128_HUMAN             Reviewed;        1094 AA.
AC   Q6ZU80; B9EK52; Q86X97; Q96ML4;
DE   RecName: Full=Centrosomal protein of 128 kDa;
DE            Short=Cep128;
GN   Name=CEP128; Synonyms=C14orf145, C14orf61;
//
ID   CE152_HUMAN             Reviewed;        1710 AA.
AC   O94986; E7ER66; Q17RV1; Q6NTA0;
DE   RecName: Full=Centrosomal protein of 152 kDa;
DE            Short=Cep152;
GN   Name=CEP152; Synonyms=KIAA0912;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0007099; P:centriole replication; ISS:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0098535; P:de novo centriole assembly; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CE162_HUMAN             Reviewed;        1403 AA.
AC   Q5TB80; A6PVL7; A6PVL8; Q6P475; Q9Y2L2;
DE   RecName: Full=Centrosomal protein of 162 kDa;
DE            Short=Cep162;
DE   AltName: Full=Protein QN1 homolog;
GN   Name=CEP162; Synonyms=C6orf84, KIAA1009, QN1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
//
ID   CE170_HUMAN             Reviewed;        1584 AA.
AC   Q5SW79; O75058; Q5SW77; Q5SW78; Q7LGA9; Q86W31; Q9UQ08; Q9UQ09;
DE   RecName: Full=Centrosomal protein of 170 kDa;
DE            Short=Cep170;
DE   AltName: Full=KARP-1-binding protein;
DE            Short=KARP1-binding protein;
GN   Name=CEP170; Synonyms=FAM68A, KAB, KIAA0470;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CE164_HUMAN             Reviewed;        1460 AA.
AC   Q9UPV0; Q6PKH9; Q7Z2X9; Q9NVS0; Q9UFJ6;
DE   RecName: Full=Centrosomal protein of 164 kDa;
DE            Short=Cep164;
GN   Name=CEP164; Synonyms=KIAA1052, NPHP15;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CE192_HUMAN             Reviewed;        1941 AA.
AC   Q8TEP8; Q8WYT8; Q9H0F4; Q9NW27;
DE   RecName: Full=Centrosomal protein of 192 kDa;
DE            Short=Cep192;
GN   Name=CEP192; Synonyms=KIAA1569; ORFNames=PP8407;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   CE290_HUMAN             Reviewed;        2479 AA.
AC   O15078; Q1PSK5; Q66GS8; Q9H2G6; Q9H6Q7; Q9H8I0;
DE   RecName: Full=Centrosomal protein of 290 kDa;
DE            Short=Cep290;
DE   AltName: Full=Bardet-Biedl syndrome 14 protein;
DE   AltName: Full=Cancer/testis antigen 87;
DE            Short=CT87;
DE   AltName: Full=Nephrocystin-6;
DE   AltName: Full=Tumor antigen se2-2;
GN   Name=CEP290; Synonyms=BBS14, KIAA0373, NPHP6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0042462; P:eye photoreceptor cell development; ISS:HGNC.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030902; P:hindbrain development; ISS:HGNC.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030916; P:otic vesicle formation; ISS:HGNC.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0048793; P:pronephros development; ISS:HGNC.
DR   GO; GO:0015031; P:protein transport; ISS:UniProtKB.
DR   GO; GO:0030814; P:regulation of cAMP metabolic process; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
//
ID   CE350_HUMAN             Reviewed;        3117 AA.
AC   Q5VT06; O75068; Q8TDK3; Q8WY20;
DE   RecName: Full=Centrosome-associated protein 350;
DE            Short=Cep350;
DE   AltName: Full=Centrosome-associated protein of 350 kDa;
GN   Name=CEP350; Synonyms=CAP350, KIAA0480; ORFNames=GM133;
//
ID   CE57L_HUMAN             Reviewed;         460 AA.
AC   Q8IYX8;
DE   RecName: Full=Centrosomal protein CEP57L1;
DE   AltName: Full=Centrosomal protein 57kDa-like protein 1;
DE   AltName: Full=Centrosomal protein of 57 kDa-related protein;
DE            Short=Cep57R;
DE   AltName: Full=Cep57-related protein;
GN   Name=CEP57L1; Synonyms=C6orf182, CEP57R;
DR   GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
//
ID   CE85L_HUMAN             Reviewed;         805 AA.
AC   Q5SZL2; A1A4E1; A2A3P2; A2IDE5; F8W6J2; G3V0H3; Q2TAM2; Q5T323;
AC   Q7Z5K7; Q9H289;
DE   RecName: Full=Centrosomal protein of 85 kDa-like;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-15;
GN   Name=CEP85L; Synonyms=C6orf204;
//
ID   CEA16_HUMAN             Reviewed;         425 AA.
AC   Q2WEN9; A7LI12;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 16;
DE   AltName: Full=Carcinoembryonic antigen-like 2;
DE   Flags: Precursor;
GN   Name=CEACAM16; Synonyms=CEAL2;
DR   GO; GO:0007605; P:sensory perception of sound; IMP:MGI.
//
ID   CEA18_HUMAN             Reviewed;         384 AA.
AC   A8MTB9; C9JN24;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 18;
DE   Flags: Precursor;
GN   Name=CEACAM18;
//
ID   CEA19_HUMAN             Reviewed;         300 AA.
AC   Q7Z692; Q5XJ15; Q7Z693;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 19;
DE   AltName: Full=Carcinoembryonic antigen-like 1;
DE   Flags: Precursor;
GN   Name=CEACAM19; Synonyms=CEAL1; ORFNames=UNQ2973/PRO7436;
//
ID   CEA20_HUMAN             Reviewed;         585 AA.
AC   Q6UY09;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 20;
DE   Flags: Precursor;
GN   Name=CEACAM20; ORFNames=UNQ9366/PRO34155;
//
ID   CEA21_HUMAN             Reviewed;         293 AA.
AC   Q3KPI0; B7WNQ6; O75296; Q6UY47; Q96ER7;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 21;
DE   Flags: Precursor;
GN   Name=CEACAM21; ORFNames=UNQ3098/PRO10075;
//
ID   CEAM1_HUMAN             Reviewed;         526 AA.
AC   P13688; A6NE38; A8MY49; O60430; Q069I7; Q13854; Q13857; Q13858;
AC   Q13859; Q13860; Q15600; Q15601; Q16170; Q5UB49; Q7KYP5; Q96CA7;
AC   Q9UQV9;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 1;
DE   AltName: Full=Biliary glycoprotein 1;
DE            Short=BGP-1;
DE   AltName: CD_antigen=CD66a;
DE   Flags: Precursor;
GN   Name=CEACAM1; Synonyms=BGP, BGP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
//
ID   CEAM3_HUMAN             Reviewed;         252 AA.
AC   P40198; Q3KPH9;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 3;
DE   AltName: Full=Carcinoembryonic antigen CGM1;
DE   AltName: CD_antigen=CD66d;
DE   Flags: Precursor;
GN   Name=CEACAM3; Synonyms=CD66D, CGM1;
//
ID   CEAM4_HUMAN             Reviewed;         244 AA.
AC   O75871; Q03715; Q7LDZ7;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 4;
DE   AltName: Full=Carcinoembryonic antigen CGM7;
DE   AltName: Full=Non-specific cross-reacting antigen W236;
DE   Flags: Precursor;
GN   Name=CEACAM4; Synonyms=CGM7;
//
ID   CEAM5_HUMAN             Reviewed;         702 AA.
AC   P06731; H9KVA7;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5;
DE   AltName: Full=Carcinoembryonic antigen;
DE            Short=CEA;
DE   AltName: Full=Meconium antigen 100;
DE   AltName: CD_antigen=CD66e;
DE   Flags: Precursor;
GN   Name=CEACAM5; Synonyms=CEA;
DR   GO; GO:0034235; F:GPI anchor binding; IMP:UniProt.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; IDA:UniProt.
DR   GO; GO:2000811; P:negative regulation of anoikis; IDA:UniProt.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProt.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; IDA:UniProt.
//
ID   CEAM6_HUMAN             Reviewed;         344 AA.
AC   P40199; Q13774; Q14920; Q53XP7;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 6;
DE   AltName: Full=Non-specific crossreacting antigen;
DE   AltName: Full=Normal cross-reacting antigen;
DE   AltName: CD_antigen=CD66c;
DE   Flags: Precursor;
GN   Name=CEACAM6; Synonyms=NCA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CEAM7_HUMAN             Reviewed;         265 AA.
AC   Q14002; A8K848; O15148; O15149; Q0VAC1; Q13983; Q9UPJ2;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 7;
DE   AltName: Full=Carcinoembryonic antigen CGM2;
DE   Flags: Precursor;
GN   Name=CEACAM7; Synonyms=CGM2;
//
ID   CEAM8_HUMAN             Reviewed;         349 AA.
AC   P31997; O60399; Q16574;
DE   RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 8;
DE   AltName: Full=CD67 antigen;
DE   AltName: Full=Carcinoembryonic antigen CGM6;
DE   AltName: Full=Non-specific cross-reacting antigen NCA-95;
DE   AltName: CD_antigen=CD66b;
DE   Flags: Precursor;
GN   Name=CEACAM8; Synonyms=CGM6;
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   CEAS1_HUMAN             Reviewed;         184 AA.
AC   Q8N7Q2; A6NFV2;
DE   RecName: Full=Putative uncharacterized protein CELF2-AS1;
DE   AltName: Full=CELF2 antisense RNA 1;
DE   AltName: Full=CELF2 antisense gene protein 1;
DE   Flags: Precursor;
GN   Name=CELF2-AS1; Synonyms=C10orf31;
//
ID   CEBPA_HUMAN             Reviewed;         358 AA.
AC   P49715; A7LNP2; P78319; Q05CA4;
DE   RecName: Full=CCAAT/enhancer-binding protein alpha;
DE            Short=C/EBP alpha;
GN   Name=CEBPA;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0030099; P:myeloid cell differentiation; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IDA:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0033274; P:response to vitamin B2; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0000050; P:urea cycle; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0050872; P:white fat cell differentiation; IEA:Ensembl.
//
ID   CEBPB_HUMAN             Reviewed;         345 AA.
AC   P17676; A8K671; Q96IH2; Q9H4Z5;
DE   RecName: Full=CCAAT/enhancer-binding protein beta;
DE            Short=C/EBP beta;
DE   AltName: Full=Liver activator protein;
DE            Short=LAP;
DE   AltName: Full=Liver-enriched inhibitory protein;
DE            Short=LIP;
DE   AltName: Full=Nuclear factor NF-IL6;
DE   AltName: Full=Transcription factor 5;
DE            Short=TCF-5;
GN   Name=CEBPB; Synonyms=TCF5; ORFNames=PP9092;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0006953; P:acute-phase response; TAS:ProtInc.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045408; P:regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060850; P:regulation of transcription involved in cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CEBPD_HUMAN             Reviewed;         269 AA.
AC   P49716; Q14937; Q2M2X9;
DE   RecName: Full=CCAAT/enhancer-binding protein delta;
DE            Short=C/EBP delta;
DE   AltName: Full=Nuclear factor NF-IL6-beta;
DE            Short=NF-IL6-beta;
GN   Name=CEBPD;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CEBPE_HUMAN             Reviewed;         281 AA.
AC   Q15744; Q15745; Q8IYI2; Q99803;
DE   RecName: Full=CCAAT/enhancer-binding protein epsilon;
DE            Short=C/EBP epsilon;
GN   Name=CEBPE;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042089; P:cytokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0006909; P:phagocytosis; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CEBPG_HUMAN             Reviewed;         150 AA.
AC   P53567; B2R946; Q5U052;
DE   RecName: Full=CCAAT/enhancer-binding protein gamma;
DE            Short=C/EBP gamma;
GN   Name=CEBPG;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0001889; P:liver development; ISS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; IEA:Ensembl.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; ISS:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0043388; P:positive regulation of DNA binding; TAS:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IEP:UniProtKB.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CEBPZ_HUMAN             Reviewed;        1054 AA.
AC   Q03701; Q8NE75;
DE   RecName: Full=CCAAT/enhancer-binding protein zeta;
DE   AltName: Full=CCAAT-box-binding transcription factor;
DE            Short=CBF;
DE            Short=CCAAT-binding factor;
GN   Name=CEBPZ; Synonyms=CBF2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CECR1_HUMAN             Reviewed;         511 AA.
AC   Q9NZK5; A8K9H4; Q6ICF1; Q86UB6; Q8NCJ2; Q96K41;
DE   RecName: Full=Adenosine deaminase CECR1;
DE            EC=3.5.4.4;
DE   AltName: Full=Cat eye syndrome critical region protein 1;
DE   Flags: Precursor;
GN   Name=CECR1; Synonyms=ADA2, ADGF, IDGFL;
DR   GO; GO:0004000; F:adenosine deaminase activity; IDA:UniProtKB.
DR   GO; GO:0031685; F:adenosine receptor binding; IDA:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0043394; F:proteoglycan binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006154; P:adenosine catabolic process; IDA:UniProtKB.
DR   GO; GO:0043103; P:hypoxanthine salvage; IBA:RefGenome.
DR   GO; GO:0046103; P:inosine biosynthetic process; IBA:RefGenome.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
//
ID   CECR5_HUMAN             Reviewed;         423 AA.
AC   Q9BXW7; B2RCK5; Q9BXW8; Q9NWA8; Q9NX41;
DE   RecName: Full=Cat eye syndrome critical region protein 5;
DE   Flags: Precursor;
GN   Name=CECR5;
//
ID   CECR2_HUMAN             Reviewed;        1484 AA.
AC   Q9BXF3; A8MS90; A8MX16; Q658Z4; Q96P58; Q9C0C3;
DE   RecName: Full=Cat eye syndrome critical region protein 2;
GN   Name=CECR2; Synonyms=KIAA1740;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:HGNC.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:MGI.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; NAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:BHF-UCL.
DR   GO; GO:0060122; P:inner ear receptor stereocilium organization; IEA:Ensembl.
DR   GO; GO:0001842; P:neural fold formation; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
//
ID   CECR9_HUMAN             Reviewed;         216 AA.
AC   P0C854;
DE   RecName: Full=Putative cat eye syndrome critical region protein 9;
DE   Flags: Precursor;
GN   Name=CECR9;
//
ID   CECR6_HUMAN             Reviewed;         578 AA.
AC   Q9BXQ6; A8MYY1;
DE   RecName: Full=Cat eye syndrome critical region protein 6;
GN   Name=CECR6;
//
ID   CEGT_HUMAN              Reviewed;         394 AA.
AC   Q16739; Q5T258;
DE   RecName: Full=Ceramide glucosyltransferase;
DE            EC=2.4.1.80;
DE   AltName: Full=GLCT-1;
DE   AltName: Full=Glucosylceramide synthase;
DE            Short=GCS;
DE   AltName: Full=UDP-glucose ceramide glucosyltransferase;
DE   AltName: Full=UDP-glucose:N-acylsphingosine D-glucosyltransferase;
GN   Name=UGCG;
DR   GuidetoPHARMACOLOGY; 2528; -.
DR   GO; GO:0008120; F:ceramide glucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0006679; P:glucosylceramide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CEI_HUMAN               Reviewed;         138 AA.
AC   Q86SI9;
DE   RecName: Full=Protein CEI;
DE   AltName: Full=Coordinated expression to IRXA2 protein;
DE   Flags: Precursor;
GN   Name=C5orf38; Synonyms=CEI;
//
ID   CEL2A_HUMAN             Reviewed;         269 AA.
AC   P08217; B2R5I4; Q14243;
DE   RecName: Full=Chymotrypsin-like elastase family member 2A;
DE            EC=3.4.21.71;
DE   AltName: Full=Elastase-2A;
DE   Flags: Precursor;
GN   Name=CELA2A; Synonyms=ELA2A;
DR   GO; GO:0017171; F:serine hydrolase activity; IDA:MGI.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
//
ID   CEL3A_HUMAN             Reviewed;         270 AA.
AC   P09093; B1AQ53; Q9BRW4;
DE   RecName: Full=Chymotrypsin-like elastase family member 3A;
DE            EC=3.4.21.70;
DE   AltName: Full=Elastase IIIA;
DE   AltName: Full=Elastase-3A;
DE   AltName: Full=Protease E;
DE   Flags: Precursor;
GN   Name=CELA3A; Synonyms=ELA3, ELA3A;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CEL2B_HUMAN             Reviewed;         269 AA.
AC   P08218; Q14D16; Q6ISM5; Q96QV5;
DE   RecName: Full=Chymotrypsin-like elastase family member 2B;
DE            EC=3.4.21.71;
DE   AltName: Full=Elastase-2B;
DE   Flags: Precursor;
GN   Name=CELA2B; Synonyms=ELA2B;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
//
ID   CEL3B_HUMAN             Reviewed;         270 AA.
AC   P08861; B2RE44; P11423; Q5VU28; Q5VU29; Q5VU30;
DE   RecName: Full=Chymotrypsin-like elastase family member 3B;
DE            EC=3.4.21.70;
DE   AltName: Full=Elastase IIIB;
DE   AltName: Full=Elastase-3B;
DE   AltName: Full=Protease E;
DE   Flags: Precursor;
GN   Name=CELA3B; Synonyms=ELA3B;
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CELA1_HUMAN             Reviewed;         258 AA.
AC   Q9UNI1; Q5MLF0; Q6DJT0; Q6ISM6;
DE   RecName: Full=Chymotrypsin-like elastase family member 1;
DE            EC=3.4.21.36;
DE   AltName: Full=Elastase-1;
DE   AltName: Full=Pancreatic elastase 1;
DE   Flags: Precursor;
GN   Name=CELA1; Synonyms=ELA1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0061113; P:pancreas morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0045595; P:regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   CELF1_HUMAN             Reviewed;         486 AA.
AC   Q92879; B4E2U5; D3DQS0; F8W940; Q4LE52; Q9NP83; Q9NR06;
DE   RecName: Full=CUGBP Elav-like family member 1;
DE            Short=CELF-1;
DE   AltName: Full=50 kDa nuclear polyadenylated RNA-binding protein;
DE   AltName: Full=Bruno-like protein 2;
DE   AltName: Full=CUG triplet repeat RNA-binding protein 1;
DE            Short=CUG-BP1;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 1;
DE   AltName: Full=Deadenylation factor CUG-BP;
DE   AltName: Full=Embryo deadenylation element-binding protein homolog;
DE            Short=EDEN-BP homolog;
DE   AltName: Full=RNA-binding protein BRUNOL-2;
GN   Name=CELF1; Synonyms=BRUNOL2, CUGBP, CUGBP1, NAB50;
DR   GO; GO:0042835; F:BRE binding; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:BHF-UCL.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006376; P:mRNA splice site selection; ISS:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; NAS:GOC.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0016246; P:RNA interference; NAS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   CELF2_HUMAN             Reviewed;         508 AA.
AC   O95319; B7ZAN9; Q7KYU4; Q8N499; Q92950; Q96NW9; Q96RQ5; Q96RQ6;
AC   Q9UL67;
DE   RecName: Full=CUGBP Elav-like family member 2;
DE            Short=CELF-2;
DE   AltName: Full=Bruno-like protein 3;
DE   AltName: Full=CUG triplet repeat RNA-binding protein 2;
DE            Short=CUG-BP2;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 2;
DE   AltName: Full=ELAV-type RNA-binding protein 3;
DE            Short=ETR-3;
DE   AltName: Full=Neuroblastoma apoptosis-related RNA-binding protein;
DE            Short=hNAPOR;
DE   AltName: Full=RNA-binding protein BRUNOL-3;
GN   Name=CELF2; Synonyms=BRUNOL3, CUGBP2, ETR3, NAPOR;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   CELF3_HUMAN             Reviewed;         465 AA.
AC   Q5SZQ8; B7ZKK6; O15414; Q499Y6; Q5SZQ7; Q6NVK0; Q8IZ98; Q9BZC2;
AC   Q9HB30;
DE   RecName: Full=CUGBP Elav-like family member 3;
DE            Short=CELF-3;
DE   AltName: Full=Bruno-like protein 1;
DE   AltName: Full=CAG repeat protein 4;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 3;
DE   AltName: Full=ELAV-type RNA-binding protein 1;
DE            Short=ETR-1;
DE   AltName: Full=Expanded repeat domain protein CAG/CTG 4;
DE   AltName: Full=RNA-binding protein BRUNOL-1;
DE   AltName: Full=Trinucleotide repeat-containing gene 4 protein;
GN   Name=CELF3; Synonyms=BRUNOL1, CAGH4, ERDA4, TNRC4;
DR   GO; GO:0003729; F:mRNA binding; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; NAS:UniProtKB.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CELF4_HUMAN             Reviewed;         486 AA.
AC   Q9BZC1; Q59EN7; Q86XB9; Q8N2M6; Q9BQ96; Q9NR84; Q9NR85;
DE   RecName: Full=CUGBP Elav-like family member 4;
DE            Short=CELF-4;
DE   AltName: Full=Bruno-like protein 4;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 4;
DE   AltName: Full=RNA-binding protein BRUNOL-4;
GN   Name=CELF4; Synonyms=BRUNOL4;
DR   GO; GO:0042835; F:BRE binding; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IDA:MGI.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; NAS:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:Ensembl.
DR   GO; GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; NAS:GOC.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
//
ID   CELF5_HUMAN             Reviewed;         485 AA.
AC   Q8N6W0; D6W614; O75253; Q59GP2; Q86VW6; Q9BZC0; Q9NR86;
DE   RecName: Full=CUGBP Elav-like family member 5;
DE            Short=CELF-5;
DE   AltName: Full=Bruno-like protein 5;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 5;
DE   AltName: Full=RNA-binding protein BRUNOL-5;
GN   Name=CELF5; Synonyms=BRUNOL5;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   CELF6_HUMAN             Reviewed;         481 AA.
AC   Q96J87; B4DG28; B4DJB6; Q6PII4; Q6ZNJ7; Q8N607;
DE   RecName: Full=CUGBP Elav-like family member 6;
DE            Short=CELF-6;
DE   AltName: Full=Bruno-like protein 6;
DE   AltName: Full=CUG-BP- and ETR-3-like factor 6;
DE   AltName: Full=RNA-binding protein BRUNOL-6;
GN   Name=CELF6; Synonyms=BRUNOL6;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
//
ID   CELR1_HUMAN             Reviewed;        3014 AA.
AC   Q9NYQ6; O95722; Q5TH47; Q9BWQ5; Q9Y506; Q9Y526;
DE   RecName: Full=Cadherin EGF LAG seven-pass G-type receptor 1;
DE   AltName: Full=Cadherin family member 9;
DE   AltName: Full=Flamingo homolog 2;
DE            Short=hFmi2;
DE   Flags: Precursor;
GN   Name=CELSR1; Synonyms=CDHF9, FMI2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; NAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0045176; P:apical protein localization; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0048105; P:establishment of body hair planar orientation; IEA:Ensembl.
DR   GO; GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
DR   GO; GO:0042249; P:establishment of planar polarity of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060490; P:lateral sprouting involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0060488; P:orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; IEA:Ensembl.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0060489; P:planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; IEA:Ensembl.
DR   GO; GO:0090251; P:protein localization involved in establishment of planar polarity; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   CELR2_HUMAN             Reviewed;        2923 AA.
AC   Q9HCU4; Q5T2Y7; Q92566;
DE   RecName: Full=Cadherin EGF LAG seven-pass G-type receptor 2;
DE   AltName: Full=Cadherin family member 10;
DE   AltName: Full=Epidermal growth factor-like protein 2;
DE            Short=EGF-like protein 2;
DE   AltName: Full=Flamingo homolog 3;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 3;
DE            Short=Multiple EGF-like domains protein 3;
DE   Flags: Precursor;
GN   Name=CELSR2; Synonyms=CDHF10, EGFL2, KIAA0279, MEGF3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0033326; P:cerebrospinal fluid secretion; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0003341; P:cilium movement; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0021999; P:neural plate anterior/posterior regionalization; ISS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; ISS:BHF-UCL.
//
ID   CELR3_HUMAN             Reviewed;        3312 AA.
AC   Q9NYQ7; O75092;
DE   RecName: Full=Cadherin EGF LAG seven-pass G-type receptor 3;
DE   AltName: Full=Cadherin family member 11;
DE   AltName: Full=Epidermal growth factor-like protein 1;
DE            Short=EGF-like protein 1;
DE   AltName: Full=Flamingo homolog 1;
DE            Short=hFmi1;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 2;
DE            Short=Multiple EGF-like domains protein 2;
DE   Flags: Precursor;
GN   Name=CELSR3; Synonyms=CDHF11, EGFL1, FMI1, KIAA0812, MEGF2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
//
ID   CEL_HUMAN               Reviewed;         753 AA.
AC   P19835; Q16398; Q5T7U7; Q9UCH1; Q9UP41;
DE   RecName: Full=Bile salt-activated lipase;
DE            Short=BAL;
DE            EC=3.1.1.13;
DE            EC=3.1.1.3;
DE   AltName: Full=Bile salt-stimulated lipase;
DE            Short=BSSL;
DE   AltName: Full=Bucelipase;
DE   AltName: Full=Carboxyl ester lipase;
DE   AltName: Full=Cholesterol esterase;
DE   AltName: Full=Pancreatic lysophospholipase;
DE   AltName: Full=Sterol esterase;
DE   Flags: Precursor;
GN   Name=CEL; Synonyms=BAL;
DR   GO; GO:0047372; F:acylglycerol lipase activity; TAS:Reactome.
DR   GO; GO:0003824; F:catalytic activity; TAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; NAS:UniProtKB.
DR   GO; GO:0016787; F:hydrolase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004771; F:sterol esterase activity; NAS:UniProtKB.
DR   GO; GO:0004806; F:triglyceride lipase activity; NAS:UniProtKB.
DR   GO; GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.
DR   GO; GO:0009062; P:fatty acid catabolic process; NAS:UniProtKB.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; NAS:UniProtKB.
DR   GO; GO:0044258; P:intestinal lipid catabolic process; NAS:UniProtKB.
DR   GO; GO:0044241; P:lipid digestion; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0030157; P:pancreatic juice secretion; IDA:UniProtKB.
DR   GO; GO:0018350; P:protein esterification; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IC:UniProtKB.
//
ID   CEMIP_HUMAN             Reviewed;        1361 AA.
AC   Q8WUJ3; Q6L9J5; Q9H1K5; Q9NPN9; Q9ULM1;
DE   RecName: Full=Cell migration-inducing and hyaluronan-binding protein;
DE            EC=3.2.1.35;
DE   Flags: Precursor;
GN   Name=CEMIP; Synonyms=KIAA1199;
DR   GO; GO:0046923; F:ER retention sequence binding; IDA:UniProtKB.
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:1900020; P:positive regulation of protein kinase C activity; IDA:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
//
ID   CEND_HUMAN              Reviewed;         149 AA.
AC   Q8N111; Q9NYM6;
DE   RecName: Full=Cell cycle exit and neuronal differentiation protein 1;
DE   AltName: Full=BM88 antigen;
GN   Name=CEND1; Synonyms=BM88;
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0021686; P:cerebellar granular layer maturation; IEA:Ensembl.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0021941; P:negative regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0021933; P:radial glia guided migration of cerebellar granule cell; IEA:Ensembl.
//
ID   CEMP1_HUMAN             Reviewed;         247 AA.
AC   Q6PRD7; B2RUY1;
DE   RecName: Full=Cementoblastoma-derived protein 1;
DE   AltName: Full=Cementum protein 1;
DE   AltName: Full=Cementum protein 23;
DE            Short=CP-23;
GN   Name=CEMP1; Synonyms=CP23;
//
ID   CENP1_HUMAN             Reviewed;         187 AA.
AC   B2RD01;
DE   RecName: Full=CENPB DNA-binding domain-containing protein 1;
GN   Name=CENPBD1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   CENPA_HUMAN             Reviewed;         140 AA.
AC   P49450; D6W544; Q53T74; Q9BVW2;
DE   RecName: Full=Histone H3-like centromeric protein A;
DE   AltName: Full=Centromere autoantigen A;
DE   AltName: Full=Centromere protein A;
DE            Short=CENP-A;
GN   Name=CENPA;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0051382; P:kinetochore assembly; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0071459; P:protein localization to chromosome, centromeric region; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CENPB_HUMAN             Reviewed;         599 AA.
AC   P07199; Q96EI4;
DE   RecName: Full=Major centromere autoantigen B;
DE   AltName: Full=Centromere protein B;
DE            Short=CENP-B;
GN   Name=CENPB;
DR   GO; GO:0019237; F:centromeric DNA binding; IC:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; NAS:UniProtKB.
DR   GO; GO:0003696; F:satellite DNA binding; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; TAS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   CENPC_HUMAN             Reviewed;         943 AA.
AC   Q03188; Q8IW27; Q9P0M5;
DE   RecName: Full=Centromere protein C;
DE            Short=CENP-C;
DE   AltName: Full=Centromere autoantigen C;
DE   AltName: Full=Centromere protein C 1;
DE            Short=CENP-C 1;
DE   AltName: Full=Interphase centromere complex protein 7;
GN   Name=CENPC; Synonyms=CENPC1, ICEN7;
DR   GO; GO:0019237; F:centromeric DNA binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
//
ID   CENPE_HUMAN             Reviewed;        2701 AA.
AC   Q02224; A6NKY9; A8K2U7; Q4LE75;
DE   RecName: Full=Centromere-associated protein E;
DE   AltName: Full=Centromere protein E;
DE            Short=CENP-E;
DE   AltName: Full=Kinesin-related protein CENPE;
DE   Flags: Precursor;
GN   Name=CENPE;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043515; F:kinetochore binding; IDA:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0051382; P:kinetochore assembly; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IMP:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007079; P:mitotic chromosome movement towards spindle pole; TAS:ProtInc.
DR   GO; GO:0000089; P:mitotic metaphase; TAS:ProtInc.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
//
ID   CENPF_HUMAN             Reviewed;        3210 AA.
AC   P49454; Q13171; Q13246; Q5VVM7;
DE   RecName: Full=Centromere protein F;
DE            Short=CENP-F;
DE   AltName: Full=AH antigen;
DE   AltName: Full=Kinetochore protein CENPF;
DE   AltName: Full=Mitosin;
DE   Flags: Precursor;
GN   Name=CENPF;
DR   GO; GO:0003682; F:chromatin binding; NAS:UniProtKB.
DR   GO; GO:0045502; F:dynein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051382; P:kinetochore assembly; NAS:UniProtKB.
DR   GO; GO:0051310; P:metaphase plate congression; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0000085; P:mitotic G2 phase; IMP:UniProtKB.
DR   GO; GO:0000087; P:mitotic M phase; IDA:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; NAS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; NAS:UniProtKB.
//
ID   CENPH_HUMAN             Reviewed;         247 AA.
AC   Q9H3R5; A8K3Y1;
DE   RecName: Full=Centromere protein H;
DE            Short=CENP-H;
DE   AltName: Full=Interphase centromere complex protein 35;
GN   Name=CENPH; Synonyms=ICEN35;
DR   GO; GO:0043515; F:kinetochore binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR   GO; GO:0051383; P:kinetochore organization; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   CENPJ_HUMAN             Reviewed;        1338 AA.
AC   Q9HC77; Q2KHM6; Q5T6R5; Q96KS5; Q9C067;
DE   RecName: Full=Centromere protein J;
DE            Short=CENP-J;
DE   AltName: Full=Centrosomal P4.1-associated protein;
DE   AltName: Full=LAG-3-associated protein;
DE   AltName: Full=LYST-interacting protein 1;
GN   Name=CENPJ; Synonyms=CPAP, LAP, LIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0051301; P:cell division; NAS:UniProtKB.
DR   GO; GO:0007099; P:centriole replication; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; TAS:UniProtKB.
DR   GO; GO:0046785; P:microtubule polymerization; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046599; P:regulation of centriole replication; IMP:UniProtKB.
//
ID   CENPI_HUMAN             Reviewed;         756 AA.
AC   Q92674; Q5JWZ9; Q96ED0;
DE   RecName: Full=Centromere protein I;
DE            Short=CENP-I;
DE   AltName: Full=FSH primary response protein 1;
DE   AltName: Full=Follicle-stimulating hormone primary response protein;
DE   AltName: Full=Interphase centromere complex protein 19;
DE   AltName: Full=Leucine-rich primary response protein 1;
GN   Name=CENPI; Synonyms=FSHPRH1, ICEN19, LRPR1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0007548; P:sex differentiation; TAS:ProtInc.
//
ID   CENPK_HUMAN             Reviewed;         269 AA.
AC   Q9BS16; Q9H4L0;
DE   RecName: Full=Centromere protein K;
DE            Short=CENP-K;
DE   AltName: Full=Interphase centromere complex protein 37;
DE   AltName: Full=Protein AF-5alpha;
DE   AltName: Full=p33;
GN   Name=CENPK; Synonyms=ICEN37; ORFNames=FKSG14;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   CENPL_HUMAN             Reviewed;         344 AA.
AC   Q8N0S6; Q5TEL5; Q96ND4;
DE   RecName: Full=Centromere protein L;
DE            Short=CENP-L;
DE   AltName: Full=Interphase centromere complex protein 33;
GN   Name=CENPL; Synonyms=C1orf155, ICEN33;
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CENPM_HUMAN             Reviewed;         180 AA.
AC   Q9NSP4; A7LM22; B1AHQ9; Q6I9W3;
DE   RecName: Full=Centromere protein M;
DE            Short=CENP-M;
DE   AltName: Full=Interphase centromere complex protein 39;
DE   AltName: Full=Proliferation-associated nuclear element protein 1;
GN   Name=CENPM; Synonyms=C22orf18, ICEN39, PANE1;
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CENPN_HUMAN             Reviewed;         339 AA.
AC   Q96H22; A8MZE6; B3KN53; B4DJD1; B4DPY7; C9JJM5; D3DUK8; E7ES30;
AC   E7ETS3; Q9NZ83;
DE   RecName: Full=Centromere protein N;
DE            Short=CENP-N;
DE   AltName: Full=Interphase centromere complex protein 32;
GN   Name=CENPN; Synonyms=C16orf60, ICEN32; ORFNames=BM-309;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007059; P:chromosome segregation; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   CENPO_HUMAN             Reviewed;         300 AA.
AC   Q9BU64; B2RDC0; D6W536; Q53T55; Q96JV3;
DE   RecName: Full=Centromere protein O;
DE            Short=CENP-O;
DE   AltName: Full=Interphase centromere complex protein 36;
GN   Name=CENPO; Synonyms=ICEN36, MCM21R;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   CENPP_HUMAN             Reviewed;         288 AA.
AC   Q6IPU0; B3KS17; Q5T9F8; Q5T9F9;
DE   RecName: Full=Centromere protein P;
DE            Short=CENP-P;
GN   Name=CENPP;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   CENPQ_HUMAN             Reviewed;         268 AA.
AC   Q7L2Z9; A8KAF1; Q6IN61; Q9NVS5;
DE   RecName: Full=Centromere protein Q;
DE            Short=CENP-Q;
GN   Name=CENPQ; Synonyms=C6orf139;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   CENPR_HUMAN             Reviewed;         177 AA.
AC   Q13352; B2R7D8; Q13353; Q5RJ42; Q5RJ44; Q5RJ45; Q7KYX2; Q96CD5;
AC   Q9UKB6;
DE   RecName: Full=Centromere protein R;
DE            Short=CENP-R;
DE   AltName: Full=Beta-3-endonexin;
DE   AltName: Full=Integrin beta-3-binding protein;
DE   AltName: Full=Nuclear receptor-interacting factor 3;
GN   Name=ITGB3BP; Synonyms=CENPR, NRIF3;
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CENPS_HUMAN             Reviewed;         138 AA.
AC   Q8N2Z9; Q8NFE5; Q8NFG5;
DE   RecName: Full=Centromere protein S;
DE            Short=CENP-S;
DE   AltName: Full=Apoptosis-inducing TAF9-like domain-containing protein 1;
DE   AltName: Full=FANCM-interacting histone fold protein 1;
DE   AltName: Full=Fanconi anemia-associated polypeptide of 16 kDa;
GN   Name=APITD1; Synonyms=CENPS, FAAP16, MHF1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; TAS:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IMP:UniProtKB.
//
ID   CENPT_HUMAN             Reviewed;         561 AA.
AC   Q96BT3; Q96I29; Q96IC6; Q96NK9; Q9H901;
DE   RecName: Full=Centromere protein T;
DE            Short=CENP-T;
DE   AltName: Full=Interphase centromere complex protein 22;
GN   Name=CENPT; Synonyms=C16orf56, ICEN22;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0051382; P:kinetochore assembly; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
//
ID   CENPU_HUMAN             Reviewed;         418 AA.
AC   Q71F23; A2RRD9; Q09GN2; Q32Q71; Q9H5G1;
DE   RecName: Full=Centromere protein U;
DE            Short=CENP-U;
DE   AltName: Full=Centromere protein of 50 kDa;
DE            Short=CENP-50;
DE   AltName: Full=Interphase centromere complex protein 24;
DE   AltName: Full=KSHV latent nuclear antigen-interacting protein 1;
DE   AltName: Full=MLF1-interacting protein;
DE   AltName: Full=Polo-box-interacting protein 1;
GN   Name=CENPU; Synonyms=ICEN24, KLIP1, MLF1IP, PBIP1;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CENPV_HUMAN             Reviewed;         275 AA.
AC   Q7Z7K6; B2RPK2; Q3L8N5; Q8NFH6;
DE   RecName: Full=Centromere protein V;
DE            Short=CENP-V;
DE   AltName: Full=Nuclear protein p30;
DE   AltName: Full=Proline-rich protein 6;
GN   Name=CENPV; Synonyms=PRR6;
DR   GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:InterPro.
DR   GO; GO:0001667; P:ameboidal cell migration; IDA:MGI.
DR   GO; GO:0034508; P:centromere complex assembly; IMP:UniProtKB.
DR   GO; GO:0031508; P:centromeric heterochromatin assembly; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0033044; P:regulation of chromosome organization; IMP:UniProtKB.
//
ID   CENPW_HUMAN             Reviewed;          88 AA.
AC   Q5EE01; A6NIR0; A6NJC2;
DE   RecName: Full=Centromere protein W;
DE            Short=CENP-W;
DE   AltName: Full=Cancer-up-regulated gene 2 protein;
GN   Name=CENPW; Synonyms=C6orf173, CUG2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0051382; P:kinetochore assembly; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
//
ID   CENPX_HUMAN             Reviewed;          81 AA.
AC   A8MT69; O00281; O00282; Q96DD4; Q96F51;
DE   RecName: Full=Centromere protein X;
DE            Short=CENP-X;
DE   AltName: Full=FANCM-interacting histone fold protein 2;
DE   AltName: Full=Fanconi anemia-associated polypeptide of 10 kDa;
DE   AltName: Full=Retinoic acid-inducible gene D9 protein homolog;
DE   AltName: Full=Stimulated by retinoic acid gene 13 protein homolog;
GN   Name=STRA13; Synonyms=CENPX, FAAP10, MHF2;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; TAS:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IMP:UniProtKB.
//
ID   CEP19_HUMAN             Reviewed;         163 AA.
AC   Q96LK0; B2RA74; Q96I48;
DE   RecName: Full=Centrosomal protein of 19 kDa;
DE            Short=Cep19;
GN   Name=CEP19; Synonyms=C3orf34; ORFNames=HSD5;
//
ID   CEP41_HUMAN             Reviewed;         373 AA.
AC   Q9BYV8; A4D1M0; B4DQ35; F5H0V6; Q7Z496; Q86TM1; Q8NFU8; Q9H6A3;
AC   Q9NPV3;
DE   RecName: Full=Centrosomal protein of 41 kDa;
DE            Short=Cep41;
DE   AltName: Full=Testis-specific gene A14 protein;
GN   Name=CEP41; Synonyms=TSGA14;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0018095; P:protein polyglutamylation; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   CEP44_HUMAN             Reviewed;         390 AA.
AC   Q9C0F1; A8K8W9; A8MW11; B3KT53; D3DP42; Q8IXZ4;
DE   RecName: Full=Centrosomal protein of 44 kDa;
DE            Short=Cep44;
DE   AltName: Full=HBV PreS1-transactivated protein 3;
DE            Short=PS1TP3;
GN   Name=CEP44; Synonyms=KIAA1712;
//
ID   CEP55_HUMAN             Reviewed;         464 AA.
AC   Q53EZ4; B2RDG8; Q32WF5; Q3MV20; Q5VY28; Q6N034; Q96H32; Q9NVS7;
DE   RecName: Full=Centrosomal protein of 55 kDa;
DE            Short=Cep55;
DE   AltName: Full=Up-regulated in colon cancer 6;
GN   Name=CEP55; Synonyms=C10orf3, URCC6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:UniProt.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000281; P:mitotic cytokinesis; IGI:MGI.
//
ID   CEP57_HUMAN             Reviewed;         500 AA.
AC   Q86XR8; A0PJH1; A8K5D0; B4DDP5; F5H5F7; Q14704; Q5JB46; Q8IXP0;
AC   Q9BVF9;
DE   RecName: Full=Centrosomal protein of 57 kDa;
DE            Short=Cep57;
DE   AltName: Full=FGF2-interacting protein;
DE   AltName: Full=Testis-specific protein 57;
DE   AltName: Full=Translokin;
GN   Name=CEP57; Synonyms=KIAA0092, TSP57;
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IPI:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:HGNC.
//
ID   CEP63_HUMAN             Reviewed;         703 AA.
AC   Q96MT8; D3DND8; D3DND9; D3DNE0; Q96CR0; Q9H8F5; Q9H8N0;
DE   RecName: Full=Centrosomal protein of 63 kDa;
DE            Short=Cep63;
GN   Name=CEP63;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007099; P:centriole replication; ISS:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; ISS:UniProtKB.
DR   GO; GO:0051225; P:spindle assembly; ISS:UniProtKB.
//
ID   CEP68_HUMAN             Reviewed;         757 AA.
AC   Q76N32; B4DRQ1; D6W5F1; D6W5F2; O60326; Q9BQ18; Q9UDM9;
DE   RecName: Full=Centrosomal protein of 68 kDa;
DE            Short=Cep68;
GN   Name=CEP68; Synonyms=KIAA0582;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
//
ID   CEP70_HUMAN             Reviewed;         597 AA.
AC   Q8NHQ1; B7Z5I8; B7Z7E8; D3DNE9; F5GZX8; Q96B31; Q9H2C3; Q9H2Z1;
AC   Q9H940;
DE   RecName: Full=Centrosomal protein of 70 kDa;
DE            Short=Cep70;
DE   AltName: Full=p10-binding protein;
GN   Name=CEP70; Synonyms=BITE;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CEP72_HUMAN             Reviewed;         647 AA.
AC   Q9P209; B4DR26; Q9BV03; Q9BWM3; Q9NVR4;
DE   RecName: Full=Centrosomal protein of 72 kDa;
DE            Short=Cep72;
GN   Name=CEP72; Synonyms=KIAA1519;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0033566; P:gamma-tubulin complex localization; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   CEP76_HUMAN             Reviewed;         659 AA.
AC   Q8TAP6; B0YJB2; B4DXG5; B4DZW1; Q658N5; Q9H9U7;
DE   RecName: Full=Centrosomal protein of 76 kDa;
DE            Short=Cep76;
GN   Name=CEP76; Synonyms=C18orf9;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046599; P:regulation of centriole replication; IMP:UniProtKB.
//
ID   CEP78_HUMAN             Reviewed;         689 AA.
AC   Q5JTW2; A1A4S8; E9PHX5; Q5BJE3; Q5JTW0; Q5JTW1; Q9H9N3;
DE   RecName: Full=Centrosomal protein of 78 kDa;
DE            Short=Cep78;
GN   Name=CEP78; Synonyms=C9orf81;
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CEP83_HUMAN             Reviewed;         693 AA.
AC   Q9Y592; A4FVB1; Q08AP1;
DE   RecName: Full=Centrosomal protein of 83 kDa;
DE            Short=Cep83;
DE   AltName: Full=Coiled-coil domain-containing protein 41;
DE   AltName: Full=Renal carcinoma antigen NY-REN-58;
GN   Name=CEP83; Synonyms=CCDC41;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0071539; P:protein localization to centrosome; IMP:MGI.
DR   GO; GO:0048278; P:vesicle docking; IMP:UniProtKB.
//
ID   CEP85_HUMAN             Reviewed;         762 AA.
AC   Q6P2H3; D3DPK4; Q5VY68; Q5VY70; Q9H6Q1; Q9H828; Q9UF52;
DE   RecName: Full=Centrosomal protein of 85 kDa;
DE            Short=Cep85;
DE   AltName: Full=Coiled-coil domain-containing protein 21;
GN   Name=CEP85; Synonyms=CCDC21;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CEP89_HUMAN             Reviewed;         783 AA.
AC   Q96ST8; B9EGA6; Q8N5J8;
DE   RecName: Full=Centrosomal protein of 89 kDa;
DE            Short=Cep89;
DE   AltName: Full=Centrosomal protein 123;
DE            Short=Cep123;
DE   AltName: Full=Coiled-coil domain-containing protein 123;
GN   Name=CEP89; Synonyms=CCDC123;
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
//
ID   CEP95_HUMAN             Reviewed;         821 AA.
AC   Q96GE4; Q96M81;
DE   RecName: Full=Centrosomal protein of 95 kDa;
DE            Short=Cep95;
DE   AltName: Full=Coiled-coil domain-containing protein 45;
GN   Name=CEP95; Synonyms=CCDC45, CEP45;
//
ID   CEP97_HUMAN             Reviewed;         865 AA.
AC   Q8IW35; B5MDY8; Q8NA71; Q9H5T9;
DE   RecName: Full=Centrosomal protein of 97 kDa;
DE            Short=Cep97;
DE   AltName: Full=Leucine-rich repeat and IQ domain-containing protein 2;
GN   Name=CEP97; Synonyms=LRRIQ2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   CEPT1_HUMAN             Reviewed;         416 AA.
AC   Q9Y6K0; Q69YJ9; Q9P0Y8;
DE   RecName: Full=Choline/ethanolaminephosphotransferase 1;
DE            Short=hCEPT1;
DE            EC=2.7.8.1;
DE            EC=2.7.8.2;
GN   Name=CEPT1; ORFNames=PRO1101;
DR   GO; GO:0004142; F:diacylglycerol cholinephosphotransferase activity; TAS:Reactome.
DR   GO; GO:0004307; F:ethanolaminephosphotransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006657; P:CDP-choline pathway; TAS:GOC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CER1_HUMAN              Reviewed;         267 AA.
AC   O95813; Q6ISJ1; Q6ISJ6; Q6ISQ2; Q6ISS1;
DE   RecName: Full=Cerberus;
DE   AltName: Full=Cerberus-related protein;
DE   AltName: Full=DAN domain family member 4;
DE   Flags: Precursor;
GN   Name=CER1; Synonyms=DAND4;
DR   GO; GO:0036122; F:BMP binding; IDA:BHF-UCL.
DR   GO; GO:0016015; F:morphogen activity; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0009948; P:anterior/posterior axis specification; ISS:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0030282; P:bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; ISS:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; ISS:BHF-UCL.
DR   GO; GO:0048263; P:determination of dorsal identity; IMP:BHF-UCL.
DR   GO; GO:0007369; P:gastrulation; ISS:BHF-UCL.
DR   GO; GO:0003419; P:growth plate cartilage chondrocyte proliferation; ISS:BHF-UCL.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000381; P:negative regulation of mesoderm development; IMP:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; IMP:BHF-UCL.
DR   GO; GO:0035582; P:sequestering of BMP in extracellular matrix; IDA:BHF-UCL.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
//
ID   CERK1_HUMAN             Reviewed;         537 AA.
AC   Q8TCT0; A0JNT4; A8K611; Q9BYB3; Q9UGE5;
DE   RecName: Full=Ceramide kinase;
DE            Short=hCERK;
DE            EC=2.7.1.138;
DE   AltName: Full=Acylsphingosine kinase;
DE   AltName: Full=Lipid kinase 4;
DE            Short=LK4;
GN   Name=CERK; Synonyms=KIAA1646;
DR   GuidetoPHARMACOLOGY; 2473; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0001729; F:ceramide kinase activity; IDA:UniProtKB.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0006672; P:ceramide metabolic process; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0046834; P:lipid phosphorylation; IDA:GOC.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERKL_HUMAN             Reviewed;         558 AA.
AC   Q49MI3; B2RPL2; B4DEY1; Q49MH9; Q49MI0; Q49MI1; Q49MI2; Q5DVJ2;
AC   Q5DVJ4; Q5DVJ5; Q6UZF6; Q6ZP59;
DE   RecName: Full=Ceramide kinase-like protein;
GN   Name=CERKL;
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   CERS1_HUMAN             Reviewed;         350 AA.
AC   P27544;
DE   RecName: Full=Ceramide synthase 1;
DE            Short=CerS1;
DE   AltName: Full=LAG1 longevity assurance homolog 1;
DE   AltName: Full=Longevity assurance gene 1 protein homolog 1;
DE   AltName: Full=Protein UOG-1;
GN   Name=CERS1; Synonyms=LAG1, LASS1, UOG1;
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; ISS:HGNC.
DR   GO; GO:0072721; P:cellular response to dithiothreitol; IDA:UniProt.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProt.
DR   GO; GO:0036146; P:cellular response to mycotoxin; IDA:UniProt.
DR   GO; GO:0071492; P:cellular response to UV-A; IDA:UniProt.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IDA:UniProt.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IDA:UniProt.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; IDA:UniProt.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERS2_HUMAN             Reviewed;         380 AA.
AC   Q96G23; D3DV06; Q5SZE5; Q9HD96; Q9NW79;
DE   RecName: Full=Ceramide synthase 2;
DE            Short=CerS2;
DE   AltName: Full=LAG1 longevity assurance homolog 2;
DE   AltName: Full=SP260;
DE   AltName: Full=Tumor metastasis-suppressor gene 1 protein;
GN   Name=CERS2; Synonyms=LASS2, TMSG1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERS3_HUMAN             Reviewed;         383 AA.
AC   Q8IU89; Q8NE64; Q8NEN6;
DE   RecName: Full=Ceramide synthase 3;
DE            Short=CerS3;
DE            EC=2.3.1.24;
DE   AltName: Full=Dihydroceramide synthase 3;
DE   AltName: Full=LAG1 longevity assurance homolog 3;
GN   Name=CERS3; Synonyms=LASS3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERS4_HUMAN             Reviewed;         394 AA.
AC   Q9HA82; D6W665;
DE   RecName: Full=Ceramide synthase 4;
DE            Short=CerS4;
DE   AltName: Full=LAG1 longevity assurance homolog 4;
GN   Name=CERS4; Synonyms=LASS4;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERS5_HUMAN             Reviewed;         392 AA.
AC   Q8N5B7; B4DV54;
DE   RecName: Full=Ceramide synthase 5;
DE            Short=CerS5;
DE            EC=2.3.1.24;
DE   AltName: Full=LAG1 longevity assurance homolog 5;
GN   Name=CERS5; Synonyms=LASS5;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; IDA:HGNC.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IDA:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERS6_HUMAN             Reviewed;         384 AA.
AC   Q6ZMG9; Q32M63; Q8N617;
DE   RecName: Full=Ceramide synthase 6;
DE            Short=CerS6;
DE   AltName: Full=LAG1 longevity assurance homolog 6;
GN   Name=CERS6; Synonyms=LASS6;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050291; F:sphingosine N-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   CERU_HUMAN              Reviewed;        1065 AA.
AC   P00450; Q14063; Q2PP18; Q9UKS4;
DE   RecName: Full=Ceruloplasmin;
DE            EC=1.16.3.1;
DE   AltName: Full=Ferroxidase;
DE   Flags: Precursor;
GN   Name=CP;
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR   GO; GO:0004322; F:ferroxidase activity; TAS:ProtInc.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CES1P_HUMAN             Reviewed;         287 AA.
AC   Q9UKY3; A2RRL8; B9ZVS2;
DE   RecName: Full=Putative inactive carboxylesterase 4;
DE   AltName: Full=Inactive carboxylesterase 1 pseudogene 1;
DE   AltName: Full=Placental carboxylesterase 3;
DE            Short=PCE-3;
DE   Flags: Precursor;
GN   Name=CES1P1; Synonyms=CES4;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
//
ID   CETN1_HUMAN             Reviewed;         172 AA.
AC   Q12798; B2R536;
DE   RecName: Full=Centrin-1;
DE   AltName: Full=Caltractin isoform 2;
GN   Name=CETN1; Synonyms=CEN1, CETN;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   CETN2_HUMAN             Reviewed;         172 AA.
AC   P41208; B2R4T4; Q53XW1;
DE   RecName: Full=Centrin-2;
DE   AltName: Full=Caltractin isoform 1;
GN   Name=CETN2; Synonyms=CALT, CEN2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007099; P:centriole replication; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CETN3_HUMAN             Reviewed;         167 AA.
AC   O15182; Q53YD2; Q9BS23;
DE   RecName: Full=Centrin-3;
GN   Name=CETN3; Synonyms=CEN3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007098; P:centrosome cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   CETP_HUMAN              Reviewed;         493 AA.
AC   P11597; Q13987; Q13988; Q53YZ1;
DE   RecName: Full=Cholesteryl ester transfer protein;
DE   AltName: Full=Lipid transfer protein I;
DE   Flags: Precursor;
GN   Name=CETP;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0017127; F:cholesterol transporter activity; IDA:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IDA:BHF-UCL.
DR   GO; GO:0005319; F:lipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:BHF-UCL.
DR   GO; GO:0005548; F:phospholipid transporter activity; IDA:BHF-UCL.
DR   GO; GO:0017129; F:triglyceride binding; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030301; P:cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IDA:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IDA:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; IDA:BHF-UCL.
DR   GO; GO:0015914; P:phospholipid transport; IDA:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:Reactome.
DR   GO; GO:0010874; P:regulation of cholesterol efflux; IMP:BHF-UCL.
DR   GO; GO:0043691; P:reverse cholesterol transport; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IDA:BHF-UCL.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
//
ID   CF015_HUMAN             Reviewed;         325 AA.
AC   Q6UXA7; B0S7V8; Q0EFA6; Q2L6G7; Q5SQ81; Q86Z05; Q9UIG3;
DE   RecName: Full=Uncharacterized protein C6orf15;
DE   AltName: Full=Protein STG;
DE   Flags: Precursor;
GN   Name=C6orf15; Synonyms=STG; ORFNames=UNQ1840/PRO3566;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
//
ID   CF001_HUMAN             Reviewed;         159 AA.
AC   Q86T20; A8K299;
DE   RecName: Full=Uncharacterized protein C6orf1;
DE   AltName: Full=Protein LBH;
DE   Flags: Precursor;
GN   Name=C6orf1; Synonyms=LBH;
//
ID   CF010_HUMAN             Reviewed;         563 AA.
AC   Q5SRN2; A2BET1; A2BET2; A6NME2; B0S7R2; B0S7R3; Q5SPI9; Q5SPJ0;
AC   Q5SPK9; Q5SPL0; Q5SRN3; Q5TG25; Q5TG26; Q8N4B6;
DE   RecName: Full=Uncharacterized protein C6orf10;
GN   Name=C6orf10;
//
ID   CF047_HUMAN             Reviewed;         294 AA.
AC   O95873; B0UXA1; B0UZ50; Q5SSS6; Q95IG0;
DE   RecName: Full=Uncharacterized protein C6orf47;
DE   AltName: Full=Protein G4;
GN   Name=C6orf47; Synonyms=G4;
//
ID   CF052_HUMAN             Reviewed;         152 AA.
AC   Q5T4I8; Q5T4I7; Q96AS6;
DE   RecName: Full=Putative uncharacterized protein C6orf52;
GN   Name=C6orf52;
//
ID   CF057_HUMAN             Reviewed;         108 AA.
AC   Q5VUM1; E1P532;
DE   RecName: Full=UPF0369 protein C6orf57;
DE   Flags: Precursor;
GN   Name=C6orf57;
//
ID   CF050_HUMAN             Reviewed;         102 AA.
AC   Q9HD87;
DE   RecName: Full=Putative uncharacterized protein C6orf50;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 19 protein;
GN   Name=C6orf50; ORFNames=NAG19;
//
ID   CF058_HUMAN             Reviewed;         330 AA.
AC   Q6P5S2; B4E1I0; Q5VUP2;
DE   RecName: Full=UPF0762 protein C6orf58;
DE   Flags: Precursor;
GN   Name=C6orf58;
//
ID   CF062_HUMAN             Reviewed;         229 AA.
AC   Q9GZU0; Q3LIB6; Q5JVZ2; Q5JVZ3; Q6IA63; Q9H1Z2;
DE   RecName: Full=Uncharacterized protein C6orf62;
DE   AltName: Full=HBV X-transactivated gene 12 protein;
DE   AltName: Full=HBV XAg-transactivated protein 12;
GN   Name=C6orf62; Synonyms=XTP12; ORFNames=Nbla00237;
//
ID   CF089_HUMAN             Reviewed;         347 AA.
AC   Q6UWU4; B4DTT1; F4NAR0; F4NAR1; Q6ZMG5; Q7Z356; Q8IZ35;
DE   RecName: Full=Bombesin receptor-activated protein C6orf89;
DE   AltName: Full=Amfion;
GN   Name=C6orf89; Synonyms=BRAP; ORFNames=UNQ177/PRO203;
DR   GO; GO:0050673; P:epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IDA:UniProtKB.
//
ID   CF100_HUMAN             Reviewed;          62 AA.
AC   Q5JQF7; B0S7Y3; B0V298; Q5SNN6; Q96KW1;
DE   RecName: Full=Putative uncharacterized protein C6orf100;
GN   Name=C6orf100;
//
ID   CF118_HUMAN             Reviewed;         469 AA.
AC   Q5T5N4; Q8TC11;
DE   RecName: Full=Uncharacterized protein C6orf118;
GN   Name=C6orf118;
//
ID   CF099_HUMAN             Reviewed;         202 AA.
AC   Q4VX62; Q4VX61;
DE   RecName: Full=Putative uncharacterized protein C6orf99;
GN   Name=C6orf99;
//
ID   CF106_HUMAN             Reviewed;         298 AA.
AC   Q9H6K1; B2R8K7; Q5VV77; Q96MG5; Q9BUR9;
DE   RecName: Full=Uncharacterized protein C6orf106;
GN   Name=C6orf106;
//
ID   CF120_HUMAN             Reviewed;         191 AA.
AC   Q7Z4R8; B4DHE9; E1P5C9;
DE   RecName: Full=UPF0669 protein C6orf120;
DE   Flags: Precursor;
GN   Name=C6orf120;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   CF122_HUMAN             Reviewed;         205 AA.
AC   Q5T6M2; Q0VD89; Q96N37;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00242;
GN   Name=LINC00242; Synonyms=C6orf122, NCRNA00242;
//
ID   CF123_HUMAN             Reviewed;          57 AA.
AC   Q9Y6Z2; E1P5C8; Q5TIG8;
DE   RecName: Full=Uncharacterized protein C6orf123;
DE   AltName: Full=Protein HGC6.2;
GN   Name=C6orf123;
//
ID   CF132_HUMAN             Reviewed;        1188 AA.
AC   Q5T0Z8; A6NI05;
DE   RecName: Full=Uncharacterized protein C6orf132;
GN   Name=C6orf132;
//
ID   CF136_HUMAN             Reviewed;         315 AA.
AC   Q5SQH8; A9R9P9; F8VX15; Q5SU01; Q6ZSB7; Q8TB84;
DE   RecName: Full=Uncharacterized protein C6orf136;
GN   Name=C6orf136;
//
ID   CF141_HUMAN             Reviewed;         244 AA.
AC   Q5SZD1; A8K1H4; Q8N400; Q96NQ1;
DE   RecName: Full=Uncharacterized protein C6orf141;
GN   Name=C6orf141;
//
ID   CF155_HUMAN             Reviewed;         130 AA.
AC   Q9H8W2; E1P533; Q5TG13;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00472;
GN   Name=LINC00472; Synonyms=C6orf155;
//
ID   CF163_HUMAN             Reviewed;         329 AA.
AC   Q5TEZ5;
DE   RecName: Full=Uncharacterized protein C6orf163;
GN   Name=C6orf163;
//
ID   CF164_HUMAN             Reviewed;          76 AA.
AC   Q5TEZ4; A6NM89;
DE   RecName: Full=Putative uncharacterized protein C6orf164;
GN   Name=C6orf164;
//
ID   CF165_HUMAN             Reviewed;         622 AA.
AC   Q8IYR0; A8K969; E1P507; Q8N9U4;
DE   RecName: Full=UPF0704 protein C6orf165;
GN   Name=C6orf165;
//
ID   CF176_HUMAN             Reviewed;         186 AA.
AC   A8K010;
DE   RecName: Full=Putative transcriptional regulator encoded by LINC00473;
GN   Name=LINC00473; Synonyms=C6orf176;
DR   GO; GO:0006351; P:transcription, DNA-templated; IMP:UniProtKB.
//
ID   CF195_HUMAN             Reviewed;         127 AA.
AC   Q96MT4; Q3SY08; Q3SY09; Q3SY10; Q5TAW4;
DE   RecName: Full=Uncharacterized protein C6orf195;
GN   Name=C6orf195;
//
ID   CF183_HUMAN             Reviewed;         404 AA.
AC   Q5T699;
DE   RecName: Full=Putative uncharacterized protein C6orf183;
GN   Name=C6orf183;
//
ID   CF223_HUMAN             Reviewed;         242 AA.
AC   Q8N319; E9PB59; Q8N575;
DE   RecName: Full=Uncharacterized protein C6orf223;
GN   Name=C6orf223;
//
ID   CF222_HUMAN             Reviewed;         652 AA.
AC   P0C671; B2RTY8;
DE   RecName: Full=Uncharacterized protein C6orf222;
GN   Name=C6orf222;
//
ID   CF218_HUMAN             Reviewed;         118 AA.
AC   Q8N0U6;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00518;
GN   Name=LINC00518; Synonyms=C6orf218;
//
ID   CF217_HUMAN             Reviewed;         271 AA.
AC   P0C7V0;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00271;
GN   Name=LINC00271; Synonyms=C6orf217, NCRNA00271;
//
ID   CF208_HUMAN             Reviewed;         128 AA.
AC   Q9H8X3; Q495C5;
DE   RecName: Full=Putative uncharacterized protein LINC00574;
GN   Name=LINC00574; Synonyms=C6orf208;
//
ID   CF211_HUMAN             Reviewed;         441 AA.
AC   Q9H993; Q96FC6; Q9UFY5;
DE   RecName: Full=UPF0364 protein C6orf211;
GN   Name=C6orf211;
//
ID   CF201_HUMAN             Reviewed;         140 AA.
AC   Q7Z4U5; A6NLI6; Q6NXN5;
DE   RecName: Full=Uncharacterized protein C6orf201;
GN   Name=C6orf201;
//
ID   CF203_HUMAN             Reviewed;         240 AA.
AC   Q9P0P8; B3KRG9;
DE   RecName: Full=Uncharacterized protein C6orf203;
GN   Name=C6orf203; ORFNames=HSPC230;
//
ID   CF226_HUMAN             Reviewed;         101 AA.
AC   Q5I0X4;
DE   RecName: Full=Uncharacterized protein C6orf226;
GN   Name=C6orf226;
//
ID   CF229_HUMAN             Reviewed;         230 AA.
AC   H3BNL8;
DE   RecName: Full=Uncharacterized protein C6orf229;
GN   Name=C6orf229;
//
ID   CFAB_HUMAN              Reviewed;         764 AA.
AC   P00751; B0QZQ6; O15006; Q29944; Q53F89; Q5JP67; Q5ST50; Q96HX6;
AC   Q9BTF5; Q9BX92;
DE   RecName: Full=Complement factor B;
DE            EC=3.4.21.47;
DE   AltName: Full=C3/C5 convertase;
DE   AltName: Full=Glycine-rich beta glycoprotein;
DE            Short=GBG;
DE   AltName: Full=PBF2;
DE   AltName: Full=Properdin factor B;
DE   Contains:
DE     RecName: Full=Complement factor B Ba fragment;
DE   Contains:
DE     RecName: Full=Complement factor B Bb fragment;
DE   Flags: Precursor;
GN   Name=CFB; Synonyms=BF, BFD;
DR   GO; GO:0001848; F:complement binding; TAS:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006956; P:complement activation; IEA:InterPro.
DR   GO; GO:0006957; P:complement activation, alternative pathway; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CFAD_HUMAN              Reviewed;         253 AA.
AC   P00746; B4DV76; Q5U5S1; Q86VJ5; Q8N4E0; Q8WZB4;
DE   RecName: Full=Complement factor D;
DE            EC=3.4.21.46;
DE   AltName: Full=Adipsin;
DE   AltName: Full=C3 convertase activator;
DE   AltName: Full=Properdin factor D;
DE   Flags: Precursor;
GN   Name=CFD; Synonyms=DF, PFD;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006957; P:complement activation, alternative pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CFAH_HUMAN              Reviewed;        1231 AA.
AC   P08603; A5PL14; P78435; Q14570; Q2TAZ5; Q38G77; Q5TFM3; Q8N708;
AC   Q9NU86;
DE   RecName: Full=Complement factor H;
DE   AltName: Full=H factor 1;
DE   Flags: Precursor;
GN   Name=CFH; Synonyms=HF, HF1, HF2;
DR   GO; GO:0043395; F:heparan sulfate proteoglycan binding; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:ProtInc.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CFAI_HUMAN              Reviewed;         583 AA.
AC   P05156; O60442;
DE   RecName: Full=Complement factor I;
DE            EC=3.4.21.45;
DE   AltName: Full=C3B/C4B inactivator;
DE   Contains:
DE     RecName: Full=Complement factor I heavy chain;
DE   Contains:
DE     RecName: Full=Complement factor I light chain;
DE   Flags: Precursor;
GN   Name=CFI; Synonyms=IF;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CFC1B_HUMAN             Reviewed;         223 AA.
AC   P0CG36; B2RCY0; B9EJD3; Q53T05; Q9GZR3;
DE   RecName: Full=Cryptic family protein 1B;
DE   Flags: Precursor;
GN   Name=CFC1B;
DR   GO; GO:0007369; P:gastrulation; IEA:UniProtKB-KW.
//
ID   CFC1_HUMAN              Reviewed;         223 AA.
AC   P0CG37; B2RCY0; B9EJD3; Q53T05; Q9GZR3;
DE   RecName: Full=Cryptic protein;
DE   AltName: Full=Cryptic family protein 1;
DE   Flags: Precursor;
GN   Name=CFC1;
DR   GO; GO:0038100; F:nodal binding; IPI:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; NAS:UniProtKB.
DR   GO; GO:0007369; P:gastrulation; IEA:UniProtKB-KW.
DR   GO; GO:0038092; P:nodal signaling pathway; IMP:UniProtKB.
//
ID   CFDP1_HUMAN             Reviewed;         299 AA.
AC   Q9UEE9; O00393; O00404; Q9UEF0; Q9UEF1; Q9UEF8;
DE   RecName: Full=Craniofacial development protein 1;
DE   AltName: Full=Bucentaur;
GN   Name=CFDP1; Synonyms=BCNT;
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
//
ID   CFLAR_HUMAN             Reviewed;         480 AA.
AC   O15519; B4DJE0; B7Z9F9; O14673; O14674; O14675; O15137; O15138;
AC   O15356; O15510; O43618; O43619; O43620; O60458; O60459; Q53TS6;
AC   Q54AF1; Q96TE4; Q9UEW1;
DE   RecName: Full=CASP8 and FADD-like apoptosis regulator;
DE   AltName: Full=Caspase homolog;
DE            Short=CASH;
DE   AltName: Full=Caspase-eight-related protein;
DE            Short=Casper;
DE   AltName: Full=Caspase-like apoptosis regulatory protein;
DE            Short=CLARP;
DE   AltName: Full=Cellular FLICE-like inhibitory protein;
DE            Short=c-FLIP;
DE   AltName: Full=FADD-like antiapoptotic molecule 1;
DE            Short=FLAME-1;
DE   AltName: Full=Inhibitor of FLICE;
DE            Short=I-FLICE;
DE   AltName: Full=MACH-related inducer of toxicity;
DE            Short=MRIT;
DE   AltName: Full=Usurpin;
DE   Contains:
DE     RecName: Full=CASP8 and FADD-like apoptosis regulator subunit p43;
DE   Contains:
DE     RecName: Full=CASP8 and FADD-like apoptosis regulator subunit p12;
DE   Flags: Precursor;
GN   Name=CFLAR; Synonyms=CASH, CASP8AP1, CLARP, MRIT;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0035877; F:death effector domain binding; IBA:RefGenome.
DR   GO; GO:0008047; F:enzyme activator activity; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:1901740; P:negative regulation of myoblast fusion; ISS:BHF-UCL.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0060544; P:regulation of necroptotic process; IDA:UniProtKB.
DR   GO; GO:0014842; P:regulation of satellite cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0014732; P:skeletal muscle atrophy; ISS:BHF-UCL.
DR   GO; GO:0007519; P:skeletal muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; ISS:BHF-UCL.
DR   GO; GO:0014866; P:skeletal myofibril assembly; ISS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CFTR_HUMAN              Reviewed;        1480 AA.
AC   P13569; Q20BG8; Q20BH2; Q2I0A1; Q2I102;
DE   RecName: Full=Cystic fibrosis transmembrane conductance regulator;
DE            Short=CFTR;
DE   AltName: Full=ATP-binding cassette sub-family C member 7;
DE   AltName: Full=Channel conductance-controlling ATPase;
DE            EC=3.6.3.49;
DE   AltName: Full=cAMP-dependent chloride channel;
GN   Name=CFTR; Synonyms=ABCC7;
DR   GuidetoPHARMACOLOGY; 707; -.
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0005224; F:ATP-binding and phosphorylation-dependent chloride channel activity; TAS:ProtInc.
DR   GO; GO:0015106; F:bicarbonate transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005260; F:channel-conductance-controlling ATPase activity; NAS:UniProtKB.
DR   GO; GO:0005254; F:chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0019869; F:chloride channel inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030301; P:cholesterol transport; IEA:Ensembl.
DR   GO; GO:0051454; P:intracellular pH elevation; ISS:UniProtKB.
DR   GO; GO:0015705; P:iodide transport; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060081; P:membrane hyperpolarization; ISS:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0048240; P:sperm capacitation; ISS:UniProtKB.
DR   GO; GO:0030321; P:transepithelial chloride transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
DR   GO; GO:0006833; P:water transport; IEA:Ensembl.
//
ID   CG013_HUMAN             Reviewed;         216 AA.
AC   Q8NI28;
DE   RecName: Full=Uncharacterized protein C7orf13;
GN   Name=C7orf13;
//
ID   CG025_HUMAN             Reviewed;         421 AA.
AC   Q9BPX7; A4D1V2; J3KR36; Q9H779;
DE   RecName: Full=UPF0415 protein C7orf25;
GN   Name=C7orf25;
//
ID   CG026_HUMAN             Reviewed;         449 AA.
AC   Q96N11; Q9BQ43;
DE   RecName: Full=Uncharacterized protein C7orf26;
GN   Name=C7orf26;
//
ID   CG031_HUMAN             Reviewed;         590 AA.
AC   Q8N865; A4D165; Q6MZV8; Q6P989; Q7LE28; Q86XK1; Q8N1H5; Q96BN4;
DE   RecName: Full=Uncharacterized protein C7orf31;
GN   Name=C7orf31;
//
ID   CG034_HUMAN             Reviewed;         122 AA.
AC   Q96L11; A4D2H8; C9JTW1; Q8TDV6;
DE   RecName: Full=Uncharacterized protein C7orf34;
DE   AltName: Full=MSSP-binding protein CTM-1;
DE   Flags: Precursor;
GN   Name=C7orf34;
//
ID   CG033_HUMAN             Reviewed;         177 AA.
AC   Q8WU49;
DE   RecName: Full=Uncharacterized protein C7orf33;
GN   Name=C7orf33;
//
ID   CG043_HUMAN             Reviewed;         580 AA.
AC   Q8WVR3; A4D2A9; D6W5U4; Q9BQJ1; Q9BUB6; Q9NV47;
DE   RecName: Full=Uncharacterized protein C7orf43;
GN   Name=C7orf43;
//
ID   CG050_HUMAN             Reviewed;         194 AA.
AC   Q9BRJ6;
DE   RecName: Full=Uncharacterized protein C7orf50;
GN   Name=C7orf50; ORFNames=FP15621;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CG055_HUMAN             Reviewed;         113 AA.
AC   Q96HJ9; B7Z4Q3; Q75M90; Q9P0B3;
DE   RecName: Full=UPF0562 protein C7orf55;
GN   Name=C7orf55; ORFNames=HSPC268;
//
ID   CG057_HUMAN             Reviewed;         295 AA.
AC   Q8NEG2; C9JBJ8;
DE   RecName: Full=Uncharacterized protein C7orf57;
GN   Name=C7orf57;
//
ID   CG061_HUMAN             Reviewed;         206 AA.
AC   Q8IZ16;
DE   RecName: Full=Uncharacterized protein C7orf61;
GN   Name=C7orf61;
//
ID   CG062_HUMAN             Reviewed;         253 AA.
AC   Q8TBZ9;
DE   RecName: Full=Uncharacterized protein C7orf62;
GN   Name=C7orf62;
//
ID   CG063_HUMAN             Reviewed;         941 AA.
AC   A5D8W1; A3KMP9; B4DYW6; B4DZP7; B9EIM7; Q6V705; Q8IY89; Q9H7C2;
DE   RecName: Full=Uncharacterized protein C7orf63;
GN   Name=C7orf63;
//
ID   CG065_HUMAN             Reviewed;         151 AA.
AC   Q6ZTY9; A4D2F8;
DE   RecName: Full=Uncharacterized protein C7orf65;
GN   Name=C7orf65;
//
ID   CG066_HUMAN             Reviewed;         115 AA.
AC   A4D0T2;
DE   RecName: Full=Uncharacterized protein C7orf66;
GN   Name=C7orf66;
//
ID   CG072_HUMAN             Reviewed;         438 AA.
AC   A4D263; A6NDX9;
DE   RecName: Full=Uncharacterized protein C7orf72;
GN   Name=C7orf72;
//
ID   CG069_HUMAN             Reviewed;         122 AA.
AC   Q9H7B7; A4D2F1; Q14CN7; Q75MJ5;
DE   RecName: Full=Uncharacterized protein C7orf69;
DE   Flags: Precursor;
GN   Name=C7orf69;
//
ID   CG071_HUMAN             Reviewed;         169 AA.
AC   A4D174;
DE   RecName: Full=Putative uncharacterized protein C7orf71;
GN   Name=C7orf71;
//
ID   CG073_HUMAN             Reviewed;          47 AA.
AC   E0CX11;
DE   RecName: Full=Uncharacterized protein C7orf73;
DE   Flags: Precursor;
GN   Name=C7orf73;
//
ID   CG076_HUMAN             Reviewed;         128 AA.
AC   Q6ZVN7;
DE   RecName: Full=Putative uncharacterized protein C7orf76;
GN   Name=C7orf76;
//
ID   CGAS_HUMAN              Reviewed;         522 AA.
AC   Q8N884; L0L2J9; Q14CV6; Q32NC9; Q5SWL0; Q5SWL1; Q96E45;
DE   RecName: Full=Cyclic GMP-AMP synthase;
DE            Short=cGAMP synthase;
DE            Short=cGAS;
DE            Short=h-cGAS;
DE            EC=2.7.7.86;
DE   AltName: Full=Mab-21 domain-containing protein 1;
GN   Name=MB21D1; Synonyms=C6orf150;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0061501; F:cyclic-GMP-AMP synthase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002218; P:activation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IDA:UniProtKB.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
//
ID   CGAT1_HUMAN             Reviewed;         532 AA.
AC   Q8TDX6; B2RBE4; Q6P9G6; Q8IUF9; Q9NSQ7; Q9NUM9;
DE   RecName: Full=Chondroitin sulfate N-acetylgalactosaminyltransferase 1;
DE            Short=CsGalNAcT-1;
DE            EC=2.4.1.174;
DE   AltName: Full=Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1;
DE            Short=Beta4GalNAcT-1;
GN   Name=CSGALNACT1; Synonyms=CHGN, GALNACT1; ORFNames=UNQ656/PRO1287;
DR   GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0047238; F:glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0047237; F:glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0008037; P:cell recognition; NAS:UniProtKB.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0050650; P:chondroitin sulfate proteoglycan biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0050653; P:chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050651; P:dermatan sulfate proteoglycan biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0030210; P:heparin biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046398; P:UDP-glucuronate metabolic process; IDA:UniProtKB.
DR   GO; GO:0019276; P:UDP-N-acetylgalactosamine metabolic process; IDA:UniProtKB.
//
ID   CGAT2_HUMAN             Reviewed;         542 AA.
AC   Q8N6G5; B3KWL7; Q6MZJ5; Q6MZP6; Q8TCH4; Q9P1I6;
DE   RecName: Full=Chondroitin sulfate N-acetylgalactosaminyltransferase 2;
DE            EC=2.4.1.174;
DE   AltName: Full=Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2;
DE            Short=Beta4GalNAcT-2;
DE            Short=GalNAcT-2;
GN   Name=CSGALNACT2; Synonyms=CHGN2, GALNACT2; ORFNames=PRO0082;
DR   GO; GO:0008376; F:acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0047237; F:glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0050650; P:chondroitin sulfate proteoglycan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050653; P:chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0050651; P:dermatan sulfate proteoglycan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050652; P:dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CGB2_HUMAN              Reviewed;         195 AA.
AC   Q6NT52; B9ZVM5;
DE   RecName: Full=Choriogonadotropin subunit beta variant 2;
DE   Flags: Precursor;
GN   Name=CGB2;
//
ID   CGB1_HUMAN              Reviewed;         187 AA.
AC   A6NKQ9; A4FVC8; A8MUK6;
DE   RecName: Full=Choriogonadotropin subunit beta variant 1;
DE   Flags: Precursor;
GN   Name=CGB1;
//
ID   CGBP1_HUMAN             Reviewed;         167 AA.
AC   Q9UFW8; D3DU38; O15183;
DE   RecName: Full=CGG triplet repeat-binding protein 1;
DE            Short=CGG-binding protein 1;
DE   AltName: Full=20 kDa CGG-binding protein;
DE   AltName: Full=p20-CGGBP DNA-binding protein;
GN   Name=CGGBP1; Synonyms=CGGBP;
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CGHB_HUMAN              Reviewed;         165 AA.
AC   P01233; A1A5E0; B9ZVP5; Q13991; Q14000; Q3KPI3; Q3SY41; Q8WTT5;
AC   Q8WXL1; Q8WXL2; Q8WXL3; Q8WXL4;
DE   RecName: Full=Choriogonadotropin subunit beta;
DE            Short=CG-beta;
DE   AltName: Full=Chorionic gonadotrophin chain beta;
DE   Flags: Precursor;
GN   Name=CGB; Synonyms=CGB3;
GN   and
GN   Name=CGB5;
GN   and
GN   Name=CGB7;
GN   and
GN   Name=CGB8;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CGL_HUMAN               Reviewed;         405 AA.
AC   P32929; B4E1R2; E9PDV0; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8;
DE   RecName: Full=Cystathionine gamma-lyase;
DE            EC=4.4.1.1;
DE   AltName: Full=Cysteine-protein sulfhydrase;
DE   AltName: Full=Gamma-cystathionase;
GN   Name=CTH;
DR   GuidetoPHARMACOLOGY; 1444; -.
DR   GO; GO:0016846; F:carbon-sulfur lyase activity; TAS:Reactome.
DR   GO; GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.
DR   GO; GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.
DR   GO; GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.
DR   GO; GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006534; P:cysteine metabolic process; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.
DR   GO; GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0044524; P:protein sulfhydration; IMP:UniProtKB.
DR   GO; GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0019346; P:transsulfuration; TAS:Reactome.
//
ID   CGNL1_HUMAN             Reviewed;        1302 AA.
AC   Q0VF96; Q05BZ4; Q52LR0; Q695C7; Q7Z2L3; Q96JV2; Q96MN6; Q9C0B4;
DE   RecName: Full=Cingulin-like protein 1;
DE   AltName: Full=Junction-associated coiled-coil protein;
DE   AltName: Full=Paracingulin;
GN   Name=CGNL1; Synonyms=JACOP, KIAA1749;
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   CGRE1_HUMAN             Reviewed;         301 AA.
AC   Q99674; A6NHV7; B4DXY8; B5MCB7; B5MCC9; B5MCP5; E7EU99; Q8N4B7;
DE   RecName: Full=Cell growth regulator with EF hand domain protein 1;
DE   AltName: Full=Cell growth regulatory gene 11 protein;
DE   AltName: Full=Hydrophobestin;
DE   Flags: Precursor;
GN   Name=CGREF1; Synonyms=CGR11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   CGRF1_HUMAN             Reviewed;         332 AA.
AC   Q99675; Q96BX2;
DE   RecName: Full=Cell growth regulator with RING finger domain protein 1;
DE   AltName: Full=Cell growth regulatory gene 19 protein;
DE   AltName: Full=RING finger protein 197;
GN   Name=CGRRF1; Synonyms=CGR19, RNF197;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   CGT_HUMAN               Reviewed;         541 AA.
AC   Q16880; B3KXU7; O00196;
DE   RecName: Full=2-hydroxyacylsphingosine 1-beta-galactosyltransferase;
DE            EC=2.4.1.45;
DE   AltName: Full=Ceramide UDP-galactosyltransferase;
DE   AltName: Full=Cerebroside synthase;
DE   AltName: Full=UDP-galactose-ceramide galactosyltransferase;
DE   Flags: Precursor;
GN   Name=UGT8; Synonyms=CGT, UGT4;
DR   GO; GO:0003851; F:2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008489; F:UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0006682; P:galactosylceramide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0030913; P:paranodal junction assembly; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0002175; P:protein localization to paranode region of axon; IEA:Ensembl.
//
ID   CH004_HUMAN             Reviewed;         106 AA.
AC   Q9NR00;
DE   RecName: Full=Uncharacterized protein C8orf4;
DE   AltName: Full=Thyroid cancer protein 1;
DE            Short=TC-1;
GN   Name=C8orf4; Synonyms=TC1;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   CH012_HUMAN             Reviewed;         104 AA.
AC   Q96KT0;
DE   RecName: Full=Uncharacterized protein C8orf12;
GN   Name=C8orf12;
//
ID   CH031_HUMAN             Reviewed;         132 AA.
AC   Q8N9H6; Q6GMU7;
DE   RecName: Full=Uncharacterized protein C8orf31;
GN   Name=C8orf31;
//
ID   CH014_HUMAN             Reviewed;          92 AA.
AC   Q96KT6;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00208;
GN   Name=LINC00208; Synonyms=C8orf14, NCRNA00208;
//
ID   CH033_HUMAN             Reviewed;         229 AA.
AC   Q9H7E9; A6NGC0; Q96BT8;
DE   RecName: Full=UPF0488 protein C8orf33;
GN   Name=C8orf33;
//
ID   CH034_HUMAN             Reviewed;         452 AA.
AC   Q49A92; A8K5X1; G3XAM6; Q8N1X0; Q8N9M7; Q8ND19; Q96Q28;
DE   RecName: Full=Uncharacterized protein C8orf34;
DE   AltName: Full=Protein VEST-1;
GN   Name=C8orf34;
//
ID   CH037_HUMAN             Reviewed;         207 AA.
AC   Q96NL8;
DE   RecName: Full=Protein C8orf37;
GN   Name=C8orf37;
//
ID   CH044_HUMAN             Reviewed;         159 AA.
AC   Q96CB5; Q9NUM6;
DE   RecName: Full=Putative uncharacterized protein C8orf44;
GN   Name=C8orf44;
//
ID   CH046_HUMAN             Reviewed;         207 AA.
AC   Q8TAG6; B2RDC3; B4DFU4; C9J814; C9JCS3;
DE   RecName: Full=Uncharacterized protein C8orf46;
GN   Name=C8orf46;
//
ID   CH048_HUMAN             Reviewed;         319 AA.
AC   Q96LL4; Q96LJ9;
DE   RecName: Full=Uncharacterized protein C8orf48;
GN   Name=C8orf48;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CH049_HUMAN             Reviewed;         230 AA.
AC   Q96NF6;
DE   RecName: Full=Putative uncharacterized protein C8orf49;
GN   Name=C8orf49;
//
ID   CH058_HUMAN             Reviewed;         365 AA.
AC   Q8NAV2; B4DI44;
DE   RecName: Full=Uncharacterized protein C8orf58;
GN   Name=C8orf58;
//
ID   CH059_HUMAN             Reviewed;         100 AA.
AC   Q8N0T1; B2RXE7; E5RFW5;
DE   RecName: Full=Uncharacterized protein C8orf59;
GN   Name=C8orf59;
//
ID   CH071_HUMAN             Reviewed;         146 AA.
AC   Q9Y4M8;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00588;
GN   Name=LINC00588; Synonyms=C8orf71;
//
ID   CH060_HUMAN             Reviewed;         160 AA.
AC   Q9HA58;
DE   RecName: Full=Putative uncharacterized protein C8orf60;
GN   Name=C8orf60;
//
ID   CH074_HUMAN             Reviewed;         294 AA.
AC   Q6P047; A2RUD6;
DE   RecName: Full=Uncharacterized protein C8orf74;
GN   Name=C8orf74;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CH076_HUMAN             Reviewed;         380 AA.
AC   Q96K31; Q53HC1;
DE   RecName: Full=Uncharacterized protein C8orf76;
GN   Name=C8orf76;
//
ID   CH079_HUMAN             Reviewed;         121 AA.
AC   Q8N9K7;
DE   RecName: Full=Uncharacterized protein KIAA1456;
GN   Name=KIAA1456; Synonyms=C8orf79;
//
ID   CH082_HUMAN             Reviewed;         216 AA.
AC   Q6P1X6; Q6GMR2; Q6P2Q7;
DE   RecName: Full=UPF0598 protein C8orf82;
GN   Name=C8orf82;
//
ID   CH086_HUMAN             Reviewed;         223 AA.
AC   Q6ZUL3; A4QPB7;
DE   RecName: Full=Uncharacterized protein C8orf86;
GN   Name=C8orf86;
//
ID   CH087_HUMAN             Reviewed;         101 AA.
AC   E5RJ46;
DE   RecName: Full=Uncharacterized protein C8orf87;
GN   Name=C8orf87;
//
ID   CH088_HUMAN             Reviewed;         117 AA.
AC   P0DMB2;
DE   RecName: Full=Uncharacterized protein C8orf88;
GN   Name=C8orf88;
DR   GO; GO:0045947; P:negative regulation of translational initiation; IEA:InterPro.
//
ID   CH10_HUMAN              Reviewed;         102 AA.
AC   P61604; O95421; Q04984; Q53X54; Q9UDH0;
DE   RecName: Full=10 kDa heat shock protein, mitochondrial;
DE            Short=Hsp10;
DE   AltName: Full=10 kDa chaperonin;
DE   AltName: Full=Chaperonin 10;
DE            Short=CPN10;
DE   AltName: Full=Early-pregnancy factor;
DE            Short=EPF;
GN   Name=HSPE1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   CH25H_HUMAN             Reviewed;         272 AA.
AC   O95992; B2RBY3;
DE   RecName: Full=Cholesterol 25-hydroxylase;
DE            EC=1.14.99.38;
DE   AltName: Full=Cholesterol 25-monooxygenase;
DE            Short=h25OH;
GN   Name=CH25H;
DR   GO; GO:0001567; F:cholesterol 25-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008395; F:steroid hydroxylase activity; TAS:Reactome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
//
ID   CH3L1_HUMAN             Reviewed;         383 AA.
AC   P36222; B2R7B0; P30923; Q8IVA4; Q96HI7;
DE   RecName: Full=Chitinase-3-like protein 1;
DE   AltName: Full=39 kDa synovial protein;
DE   AltName: Full=Cartilage glycoprotein 39;
DE            Short=CGP-39;
DE            Short=GP-39;
DE            Short=hCGP-39;
DE   AltName: Full=YKL-40;
DE   Flags: Precursor;
GN   Name=CHI3L1;
DR   GO; GO:0008061; F:chitin binding; IDA:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0051216; P:cartilage development; NAS:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:UniProtKB.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEP:UniProtKB.
DR   GO; GO:0072606; P:interleukin-8 secretion; ISS:UniProtKB.
DR   GO; GO:0030324; P:lung development; IMP:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0070555; P:response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0070741; P:response to interleukin-6; IEP:UniProtKB.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEP:UniProtKB.
//
ID   CH3L2_HUMAN             Reviewed;         390 AA.
AC   Q15782; A6NNY3; B4DPR7; Q15749; Q15783; Q5VUV7; Q96F97;
DE   RecName: Full=Chitinase-3-like protein 2;
DE   AltName: Full=Chondrocyte protein 39;
DE   AltName: Full=YKL-39;
DE   Flags: Precursor;
GN   Name=CHI3L2;
DR   GO; GO:0008061; F:chitin binding; IDA:UniProtKB.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:InterPro.
//
ID   CH60_HUMAN              Reviewed;         573 AA.
AC   P10809; B2R5M6; Q38L19; Q9UCR6;
DE   RecName: Full=60 kDa heat shock protein, mitochondrial;
DE   AltName: Full=60 kDa chaperonin;
DE   AltName: Full=Chaperonin 60;
DE            Short=CPN60;
DE   AltName: Full=Heat shock protein 60;
DE            Short=HSP-60;
DE            Short=Hsp60;
DE   AltName: Full=HuCHA60;
DE   AltName: Full=Mitochondrial matrix protein P1;
DE   AltName: Full=P60 lymphocyte protein;
DE   Flags: Precursor;
GN   Name=HSPD1; Synonyms=HSP60;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:BHF-UCL.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
DR   GO; GO:0003688; F:DNA replication origin binding; ISS:BHF-UCL.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:BHF-UCL.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:BHF-UCL.
DR   GO; GO:0051082; F:unfolded protein binding; IC:UniProtKB.
DR   GO; GO:0006458; P:'de novo' protein folding; ISS:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0042113; P:B cell activation; IDA:BHF-UCL.
DR   GO; GO:0002368; P:B cell cytokine production; IDA:BHF-UCL.
DR   GO; GO:0042100; P:B cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; ISS:BHF-UCL.
DR   GO; GO:0048291; P:isotype switching to IgG isotypes; IDA:BHF-UCL.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IDA:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IDA:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IDA:BHF-UCL.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IDA:BHF-UCL.
DR   GO; GO:0002842; P:positive regulation of T cell mediated immune response to tumor cell; IDA:BHF-UCL.
DR   GO; GO:0051604; P:protein maturation; ISS:BHF-UCL.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IDA:BHF-UCL.
DR   GO; GO:0042110; P:T cell activation; IDA:MGI.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CHAC1_HUMAN             Reviewed;         264 AA.
AC   Q9BUX1; Q0VIA0;
DE   RecName: Full=Cation transport regulator-like protein 1;
DE   AltName: Full=Blocks Notch protein;
DE            Short=Botch;
GN   Name=CHAC1; Synonyms=BOTCH;
DR   GO; GO:0005112; F:Notch binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:UniProtKB.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.
DR   GO; GO:0010955; P:negative regulation of protein processing; IMP:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   CHAC2_HUMAN             Reviewed;         184 AA.
AC   Q8WUX2; Q8WVI8;
DE   RecName: Full=Cation transport regulator-like protein 2;
GN   Name=CHAC2;
//
ID   CHADL_HUMAN             Reviewed;         762 AA.
AC   Q6NUI6; Q05CY2; Q4G0S0; Q5JY13; Q86XY1; Q96E60;
DE   RecName: Full=Chondroadherin-like protein;
DE   Flags: Precursor;
GN   Name=CHADL; Synonyms=SLRR4B;
//
ID   CHAD_HUMAN              Reviewed;         359 AA.
AC   O15335; A8K812; Q6GTU0; Q96RJ5;
DE   RecName: Full=Chondroadherin;
DE   AltName: Full=Cartilage leucine-rich protein;
DE   Flags: Precursor;
GN   Name=CHAD; Synonyms=SLRR4A;
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
//
ID   CHAP1_HUMAN             Reviewed;         812 AA.
AC   Q96JM3; B3KU06; Q6P181; Q8NC88; Q9BST0;
DE   RecName: Full=Chromosome alignment-maintaining phosphoprotein 1;
DE   AltName: Full=Zinc finger protein 828;
GN   Name=CHAMP1; Synonyms=C13orf8, CAMP, KIAA1802, ZNF828;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.
DR   GO; GO:0035372; P:protein localization to microtubule; IMP:UniProtKB.
DR   GO; GO:0031134; P:sister chromatid biorientation; IMP:UniProtKB.
//
ID   CHC10_HUMAN             Reviewed;         142 AA.
AC   Q8WYQ3; A8K0J5;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial;
DE   AltName: Full=Protein N27C7-4;
DE   Flags: Precursor;
GN   Name=CHCHD10; Synonyms=C22orf16;
DR   GO; GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:2000984; P:negative regulation of ATP citrate synthase activity; IMP:BHF-UCL.
DR   GO; GO:0006119; P:oxidative phosphorylation; IMP:BHF-UCL.
//
ID   CHCH2_HUMAN             Reviewed;         151 AA.
AC   Q9Y6H1; Q498C3; Q6NZ50;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial;
DE   AltName: Full=Aging-associated gene 10 protein;
DE   AltName: Full=HCV NS2 trans-regulated protein;
DE            Short=NS2TP;
DE   Flags: Precursor;
GN   Name=CHCHD2; Synonyms=C7orf17; ORFNames=AAG10;
//
ID   CHCH1_HUMAN             Reviewed;         118 AA.
AC   Q96BP2;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 1;
DE   AltName: Full=28S ribosomal protein S37, mitochondrial;
DE            Short=MRP-S37;
DE   AltName: Full=Nuclear protein C2360;
GN   Name=CHCHD1; Synonyms=C10orf34, MRPS37;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CHCH5_HUMAN             Reviewed;         110 AA.
AC   Q9BSY4; Q585T4;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 5;
GN   Name=CHCHD5; Synonyms=C2orf9;
//
ID   CHCH3_HUMAN             Reviewed;         227 AA.
AC   Q9NX63;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial;
GN   Name=CHCHD3; Synonyms=MINOS3;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; ISS:UniProtKB.
DR   GO; GO:0001227; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0007007; P:inner mitochondrial membrane organization; IMP:UniProtKB.
DR   GO; GO:0008053; P:mitochondrial fusion; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   CHCH6_HUMAN             Reviewed;         235 AA.
AC   Q9BRQ6; D6R9U0; D6RIB4; H8Y0Y7;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial;
DE   AltName: Full=Coiled-coil-helix cristae morphology protein 1;
GN   Name=CHCHD6; Synonyms=CHCM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0042407; P:cristae formation; IMP:UniProtKB.
//
ID   CHCH7_HUMAN             Reviewed;          85 AA.
AC   Q9BUK0; A8K223; E9PBH3; J3KNE9; Q7Z588;
DE   RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 7;
GN   Name=CHCHD7;
//
ID   CHCH9_HUMAN             Reviewed;         151 AA.
AC   Q5T1J5;
DE   RecName: Full=Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial;
DE   AltName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9;
DE   Flags: Precursor;
GN   Name=CHCHD2P9; Synonyms=C9orf49, CHCHD9;
//
ID   CHD1L_HUMAN             Reviewed;         897 AA.
AC   Q86WJ1; A5YM64; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86XH3; Q96HF7;
AC   Q96SP3; Q9BVJ1; Q9NVV8;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 1-like;
DE            EC=3.6.4.12;
DE   AltName: Full=Amplified in liver cancer protein 1;
GN   Name=CHD1L; Synonyms=ALC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:GOC.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:UniProtKB.
//
ID   CHD1_HUMAN              Reviewed;        1710 AA.
AC   O14646; Q17RZ3;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 1;
DE            Short=CHD-1;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD1;
GN   Name=CHD1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD2_HUMAN              Reviewed;        1828 AA.
AC   O14647; C6G482; Q96IP5;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 2;
DE            Short=CHD-2;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD2;
GN   Name=CHD2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042393; F:histone binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD3_HUMAN              Reviewed;        2000 AA.
AC   Q12873; D3DTQ9; E9PG89; Q9Y4I0;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 3;
DE            Short=CHD-3;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD3;
DE   AltName: Full=Mi-2 autoantigen 240 kDa protein;
DE   AltName: Full=Mi2-alpha;
DE   AltName: Full=Zinc finger helicase;
DE            Short=hZFH;
GN   Name=CHD3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004386; F:helicase activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IDA:UniProtKB.
DR   GO; GO:0006333; P:chromatin assembly or disassembly; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD4_HUMAN              Reviewed;        1912 AA.
AC   Q14839; Q8IXZ5;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 4;
DE            Short=CHD-4;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD4;
DE   AltName: Full=Mi-2 autoantigen 218 kDa protein;
DE   AltName: Full=Mi2-beta;
GN   Name=CHD4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD5_HUMAN              Reviewed;        1954 AA.
AC   Q8TDI0; O75032; Q5TG89; Q7LGH2; Q9UFR9;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 5;
DE            Short=CHD-5;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD5;
GN   Name=CHD5; Synonyms=KIAA0444;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0098532; P:histone H3-K27 trimethylation; IMP:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:1901798; P:positive regulation of signal transduction by p53 class mediator; ISS:UniProtKB.
DR   GO; GO:0060850; P:regulation of transcription involved in cell fate commitment; IMP:UniProtKB.
DR   GO; GO:0035093; P:spermatogenesis, exchange of chromosomal proteins; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD6_HUMAN              Reviewed;        2715 AA.
AC   Q8TD26; Q5JYQ0; Q5TGZ9; Q5TH00; Q5TH01; Q8IZR2; Q8WTY0; Q9H4H6;
AC   Q9H6D4; Q9NTT7; Q9P2L1;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 6;
DE            Short=CHD-6;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD6;
DE   AltName: Full=Radiation-induced gene B protein;
GN   Name=CHD6; Synonyms=CHD5, KIAA1335, RIGB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0001221; F:transcription cofactor binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0036091; P:positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD7_HUMAN              Reviewed;        2997 AA.
AC   Q9P2D1; D0VBA5; E9PNZ2; Q05DI5; Q2TAN4; Q66K35; Q7Z6C0; Q7Z7Q2;
AC   Q9NXA0; Q9NXA3;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 7;
DE            Short=CHD-7;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD7;
GN   Name=CHD7; Synonyms=KIAA1416;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; TAS:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007512; P:adult heart development; IEA:Ensembl.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IMP:BHF-UCL.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0050890; P:cognition; IMP:BHF-UCL.
DR   GO; GO:0021545; P:cranial nerve development; IMP:BHF-UCL.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060324; P:face development; IMP:BHF-UCL.
DR   GO; GO:0030540; P:female genitalia development; IEA:Ensembl.
DR   GO; GO:0048806; P:genitalia development; IMP:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IMP:BHF-UCL.
DR   GO; GO:0042472; P:inner ear morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060173; P:limb development; IMP:BHF-UCL.
DR   GO; GO:0043584; P:nose development; IMP:BHF-UCL.
DR   GO; GO:0060021; P:palate development; IMP:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0060123; P:regulation of growth hormone secretion; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:BHF-UCL.
DR   GO; GO:0060041; P:retina development in camera-type eye; IMP:BHF-UCL.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IMP:BHF-UCL.
DR   GO; GO:0030217; P:T cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD8_HUMAN              Reviewed;        2581 AA.
AC   Q9HCK8; Q4G0D8; Q68DQ0; Q6DKH9; Q6P440; Q6ZNL7; Q8N3Z9; Q8NCY4;
AC   Q8TBR9; Q96F26;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 8;
DE            Short=CHD-8;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD8;
DE   AltName: Full=Helicase with SNF2 domain 1;
GN   Name=CHD8; Synonyms=HELSNF1, KIAA1564;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; IMP:UniProtKB.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; ISS:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IMP:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IMP:GOC.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHD9_HUMAN              Reviewed;        2897 AA.
AC   Q3L8U1; B2RTU2; B9ZVQ0; O15025; Q1WF12; Q6DTK9; Q9H9V7; Q9UHM2;
DE   RecName: Full=Chromodomain-helicase-DNA-binding protein 9;
DE            Short=CHD-9;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase CHD9;
DE   AltName: Full=Chromatin-related mesenchymal modulator;
DE            Short=CReMM;
DE   AltName: Full=Chromatin-remodeling factor CHROM1;
DE   AltName: Full=Kismet homolog 2;
DE   AltName: Full=PPAR-alpha-interacting complex protein 320 kDa;
DE   AltName: Full=Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein;
GN   Name=CHD9; Synonyms=KIAA0308, KISH2, PRIC320; ORFNames=AD-013, x0008;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHDC2_HUMAN             Reviewed;         502 AA.
AC   Q8N9S7;
DE   RecName: Full=Calponin homology domain-containing protein 2;
GN   Name=CHDC2; Synonyms=CXorf59;
//
ID   CHDH_HUMAN              Reviewed;         594 AA.
AC   Q8NE62; Q9NY17;
DE   RecName: Full=Choline dehydrogenase, mitochondrial;
DE            Short=CDH;
DE            Short=CHD;
DE            EC=1.1.99.1;
DE   Flags: Precursor;
GN   Name=CHDH;
DR   GO; GO:0008812; F:choline dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0019285; P:glycine betaine biosynthetic process from choline; IEA:UniProtKB-UniPathway.
//
ID   CHERP_HUMAN             Reviewed;         916 AA.
AC   Q8IWX8; O00302; Q4G0Y5; Q8WU30; Q99492;
DE   RecName: Full=Calcium homeostasis endoplasmic reticulum protein;
DE   AltName: Full=ERPROT 213-21;
DE   AltName: Full=SR-related CTD-associated factor 6;
GN   Name=CHERP; Synonyms=DAN26, SCAF6;
DR   GO; GO:0044325; F:ion channel binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051533; P:positive regulation of NFAT protein import into nucleus; IMP:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   CHFR_HUMAN              Reviewed;         664 AA.
AC   Q96EP1; A6NEN5; B4DZ77; B4E2L6; Q96SL3; Q9NRT4; Q9NT32; Q9NVD5;
DE   RecName: Full=E3 ubiquitin-protein ligase CHFR;
DE            EC=6.3.2.-;
DE   AltName: Full=Checkpoint with forkhead and RING finger domains protein;
DE   AltName: Full=RING finger protein 196;
GN   Name=CHFR; Synonyms=RNF196;
DR   GO; GO:0000166; F:nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0019941; P:modification-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   CHIA_HUMAN              Reviewed;         476 AA.
AC   Q9BZP6; Q32W79; Q32W80; Q3B866; Q5U5Z5; Q5VUV4; Q86UD8; Q9ULY3;
AC   Q9ULY4;
DE   RecName: Full=Acidic mammalian chitinase;
DE            Short=AMCase;
DE            EC=3.2.1.14;
DE   AltName: Full=Lung-specific protein TSA1902;
DE   Flags: Precursor;
GN   Name=CHIA;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0008061; F:chitin binding; TAS:UniProtKB.
DR   GO; GO:0004568; F:chitinase activity; IDA:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0003796; F:lysozyme activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006037; P:cell wall chitin metabolic process; TAS:UniProtKB.
DR   GO; GO:0006032; P:chitin catabolic process; IDA:UniProtKB.
DR   GO; GO:0006030; P:chitin metabolic process; NAS:UniProtKB.
DR   GO; GO:0007586; P:digestion; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IDA:UniProtKB.
DR   GO; GO:0002532; P:production of molecular mediator involved in inflammatory response; IDA:UniProtKB.
DR   GO; GO:0001101; P:response to acid; TAS:UniProtKB.
DR   GO; GO:0009620; P:response to fungus; TAS:UniProtKB.
//
ID   CHIC1_HUMAN             Reviewed;         224 AA.
AC   Q5VXU3; A0PJZ2; B0QZ87; B9EGS5; Q5CZ84;
DE   RecName: Full=Cysteine-rich hydrophobic domain 1 protein;
DE   AltName: Full=Brain X-linked protein;
GN   Name=CHIC1; Synonyms=BRX;
//
ID   CHIC2_HUMAN             Reviewed;         165 AA.
AC   Q9UKJ5; B2R639;
DE   RecName: Full=Cysteine-rich hydrophobic domain 2 protein;
DE   AltName: Full=BrX-like translocated in leukemia;
GN   Name=CHIC2; Synonyms=BTL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CHID1_HUMAN             Reviewed;         393 AA.
AC   Q9BWS9; B3KWB0; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BY52;
DE   RecName: Full=Chitinase domain-containing protein 1;
DE   AltName: Full=Stabilin-1-interacting chitinase-like protein;
DE            Short=SI-CLP;
DE   Flags: Precursor;
GN   Name=CHID1; ORFNames=GL008, PSEC0104, SB139;
DR   GO; GO:0004568; F:chitinase activity; IEA:InterPro.
DR   GO; GO:0070492; F:oligosaccharide binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:1900016; P:negative regulation of cytokine production involved in inflammatory response; IDA:UniProt.
//
ID   CHIN_HUMAN              Reviewed;         459 AA.
AC   P15882; A8K1M6; B3KNU6; B4DV19; Q53SD6; Q53SH5; Q96FB0;
DE   RecName: Full=N-chimaerin;
DE   AltName: Full=A-chimaerin;
DE   AltName: Full=Alpha-chimerin;
DE   AltName: Full=N-chimerin;
DE            Short=NC;
DE   AltName: Full=Rho GTPase-activating protein 2;
GN   Name=CHN1; Synonyms=ARHGAP2, CHN;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008045; P:motor neuron axon guidance; ISS:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   CHIO_HUMAN              Reviewed;         468 AA.
AC   P52757; A4D1A2; B3VCF1; B3VCF2; B3VCF3; B3VCF7; B3VCG1; C9J7B0;
AC   E9PGE0; F8QPL9; Q2M203; Q75MM2;
DE   RecName: Full=Beta-chimaerin;
DE   AltName: Full=Beta-chimerin;
DE   AltName: Full=Rho GTPase-activating protein 3;
GN   Name=CHN2; Synonyms=ARHGAP3, BCH;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   CHIP_HUMAN              Reviewed;         303 AA.
AC   Q9UNE7; A2IDB9; O60526; Q969U2; Q9HBT1;
DE   RecName: Full=E3 ubiquitin-protein ligase CHIP;
DE            EC=6.3.2.-;
DE   AltName: Full=Antigen NY-CO-7;
DE   AltName: Full=CLL-associated antigen KW-8;
DE   AltName: Full=Carboxy terminus of Hsp70-interacting protein;
DE   AltName: Full=STIP1 homology and U box-containing protein 1;
GN   Name=STUB1; Synonyms=CHIP; ORFNames=PP1131;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; IDA:HGNC.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0051787; F:misfolded protein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; TAS:HGNC.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0030911; F:TPR domain binding; IDA:HGNC.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; ISS:UniProtKB.
DR   GO; GO:0071218; P:cellular response to misfolded protein; IDA:BHF-UCL.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0090035; P:positive regulation of chaperone-mediated protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:HGNC.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:HGNC.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051604; P:protein maturation; TAS:HGNC.
DR   GO; GO:0000209; P:protein polyubiquitination; IMP:UniProtKB.
DR   GO; GO:0031943; P:regulation of glucocorticoid metabolic process; IDA:HGNC.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:HGNC.
//
ID   CHIT1_HUMAN             Reviewed;         466 AA.
AC   Q13231; B3KNW6; J3KN09; Q0VGG5; Q0VGG6; Q3ZAR1; Q6ISC2; Q9H3V8;
AC   Q9UDJ8;
DE   RecName: Full=Chitotriosidase-1;
DE            EC=3.2.1.14;
DE   AltName: Full=Chitinase-1;
DE   Flags: Precursor;
GN   Name=CHIT1;
DR   GO; GO:0008061; F:chitin binding; TAS:UniProtKB.
DR   GO; GO:0004568; F:chitinase activity; TAS:UniProtKB.
DR   GO; GO:0008843; F:endochitinase activity; IDA:UniProtKB.
DR   GO; GO:0006032; P:chitin catabolic process; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009617; P:response to bacterium; TAS:ProtInc.
//
ID   CHK1_HUMAN              Reviewed;         476 AA.
AC   O14757; A8K934; B4DDD0; B4DSK3; B5BTY6; F5H7S4; H2BI51;
DE   RecName: Full=Serine/threonine-protein kinase Chk1;
DE            EC=2.7.11.1;
DE   AltName: Full=CHK1 checkpoint homolog;
DE   AltName: Full=Cell cycle checkpoint kinase;
DE   AltName: Full=Checkpoint kinase-1;
GN   Name=CHEK1; Synonyms=CHK1;
DR   GuidetoPHARMACOLOGY; 1987; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0071313; P:cellular response to caffeine; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0035407; P:histone H3-T11 phosphorylation; IDA:GOC.
DR   GO; GO:0045839; P:negative regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.
DR   GO; GO:0046602; P:regulation of mitotic centrosome separation; IDA:UniProtKB.
DR   GO; GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB.
DR   GO; GO:0090399; P:replicative senescence; NAS:BHF-UCL.
//
ID   CHK2_HUMAN              Reviewed;         543 AA.
AC   O96017; A8K3Y9; B7ZBF3; B7ZBF4; B7ZBF5; Q6QA03; Q6QA04; Q6QA05;
AC   Q6QA06; Q6QA07; Q6QA08; Q6QA10; Q6QA11; Q6QA12; Q6QA13; Q9HBS5;
AC   Q9HCQ8; Q9UGF0; Q9UGF1;
DE   RecName: Full=Serine/threonine-protein kinase Chk2;
DE            EC=2.7.11.1;
DE   AltName: Full=CHK2 checkpoint homolog;
DE   AltName: Full=Cds1 homolog;
DE            Short=Hucds1;
DE            Short=hCds1;
DE   AltName: Full=Checkpoint kinase 2;
GN   Name=CHEK2; Synonyms=CDS1, CHK2, RAD53;
DR   GuidetoPHARMACOLOGY; 1988; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; TAS:UniProtKB.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0090399; P:replicative senescence; NAS:BHF-UCL.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IDA:MGI.
DR   GO; GO:0072428; P:signal transduction involved in intra-S DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHKA_HUMAN              Reviewed;         457 AA.
AC   P35790; Q8NE29;
DE   RecName: Full=Choline kinase alpha;
DE            Short=CK;
DE            EC=2.7.1.32;
DE   AltName: Full=CHETK-alpha;
DE   AltName: Full=Ethanolamine kinase;
DE            Short=EK;
DE            EC=2.7.1.82;
GN   Name=CHKA; Synonyms=CHK, CKI;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0033265; F:choline binding; IEA:Ensembl.
DR   GO; GO:0004103; F:choline kinase activity; IDA:UniProtKB.
DR   GO; GO:0004104; F:cholinesterase activity; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006657; P:CDP-choline pathway; IDA:GOC.
DR   GO; GO:0019695; P:choline metabolic process; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; TAS:ProtInc.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHKB_HUMAN              Reviewed;         395 AA.
AC   Q9Y259; A0PJM6; Q13388;
DE   RecName: Full=Choline/ethanolamine kinase;
DE   AltName: Full=Choline kinase beta;
DE            Short=CK;
DE            Short=CKB;
DE            EC=2.7.1.32;
DE   AltName: Full=Choline kinase-like protein;
DE   AltName: Full=Ethanolamine kinase;
DE            Short=EK;
DE            EC=2.7.1.82;
DE   AltName: Full=Ethanolamine kinase beta;
DE            Short=EKB;
DE   AltName: Full=choline/ethanolamine kinase beta;
DE            Short=CKEKB;
GN   Name=CHKB; Synonyms=CHETK, CHKL;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004103; F:choline kinase activity; IDA:UniProtKB.
DR   GO; GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006657; P:CDP-choline pathway; IDA:GOC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHL1_HUMAN              Reviewed;        1208 AA.
AC   O00533; B7ZL03; Q2M3G2; Q59FY0;
DE   RecName: Full=Neural cell adhesion molecule L1-like protein;
DE   AltName: Full=Close homolog of L1;
DE   Contains:
DE     RecName: Full=Processed neural cell adhesion molecule L1-like protein;
DE   Flags: Precursor;
GN   Name=CHL1; Synonyms=CALL;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0050890; P:cognition; IEA:Ensembl.
DR   GO; GO:0035640; P:exploration behavior; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CHLE_HUMAN              Reviewed;         602 AA.
AC   P06276; A8K7P8;
DE   RecName: Full=Cholinesterase;
DE            EC=3.1.1.8;
DE   AltName: Full=Acylcholine acylhydrolase;
DE   AltName: Full=Butyrylcholine esterase;
DE   AltName: Full=Choline esterase II;
DE   AltName: Full=Pseudocholinesterase;
DE   Flags: Precursor;
GN   Name=BCHE; Synonyms=CHE1;
DR   GuidetoPHARMACOLOGY; 2471; -.
DR   GO; GO:0003990; F:acetylcholinesterase activity; ISS:UniProtKB.
DR   GO; GO:0001540; F:beta-amyloid binding; NAS:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; NAS:UniProtKB.
DR   GO; GO:0033265; F:choline binding; IEA:Ensembl.
DR   GO; GO:0004104; F:cholinesterase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019695; P:choline metabolic process; IBA:RefGenome.
DR   GO; GO:0050783; P:cocaine metabolic process; TAS:UniProtKB.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0050805; P:negative regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0014016; P:neuroblast differentiation; IEA:Ensembl.
DR   GO; GO:0043279; P:response to alkaloid; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IBA:RefGenome.
//
ID   CHM1B_HUMAN             Reviewed;         199 AA.
AC   Q7LBR1; Q96E89; Q9HD41;
DE   RecName: Full=Charged multivesicular body protein 1b;
DE   AltName: Full=CHMP1.5;
DE   AltName: Full=Chromatin-modifying protein 1b;
DE            Short=CHMP1b;
DE   AltName: Full=Vacuolar protein sorting-associated protein 46-2;
DE            Short=Vps46-2;
DE            Short=hVps46-2;
GN   Name=CHMP1B; Synonyms=C18orf2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   CHM1A_HUMAN             Reviewed;         196 AA.
AC   Q9HD42; A2RU09; Q14468; Q15779; Q96G31;
DE   RecName: Full=Charged multivesicular body protein 1a;
DE   AltName: Full=Chromatin-modifying protein 1a;
DE            Short=CHMP1a;
DE   AltName: Full=Vacuolar protein sorting-associated protein 46-1;
DE            Short=Vps46-1;
DE            Short=hVps46-1;
GN   Name=CHMP1A; Synonyms=CHMP1, KIAA0047, PCOLN3, PRSM1;
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0016458; P:gene silencing; IDA:UniProtKB.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
DR   GO; GO:0045014; P:negative regulation of transcription by glucose; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; TAS:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:UniProtKB.
//
ID   CHM2A_HUMAN             Reviewed;         222 AA.
AC   O43633; B2R4W6; Q3ZTT0;
DE   RecName: Full=Charged multivesicular body protein 2a;
DE   AltName: Full=Chromatin-modifying protein 2a;
DE            Short=CHMP2a;
DE   AltName: Full=Putative breast adenocarcinoma marker BC-2;
DE   AltName: Full=Vacuolar protein sorting-associated protein 2-1;
DE            Short=Vps2-1;
DE            Short=hVps2-1;
GN   Name=CHMP2A; Synonyms=BC2, CHMP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:UniProt.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHM2B_HUMAN             Reviewed;         213 AA.
AC   Q9UQN3; B4DJG8; Q53HC7; Q9Y4U6;
DE   RecName: Full=Charged multivesicular body protein 2b;
DE   AltName: Full=CHMP2.5;
DE   AltName: Full=Chromatin-modifying protein 2b;
DE            Short=CHMP2b;
DE   AltName: Full=Vacuolar protein sorting-associated protein 2-2;
DE            Short=Vps2-2;
DE            Short=hVps2-2;
GN   Name=CHMP2B; ORFNames=CGI-84;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHM4A_HUMAN             Reviewed;         222 AA.
AC   Q9BY43; Q32Q79; Q86SZ8; Q96QJ9; Q9P026;
DE   RecName: Full=Charged multivesicular body protein 4a;
DE   AltName: Full=Chromatin-modifying protein 4a;
DE            Short=CHMP4a;
DE   AltName: Full=SNF7 homolog associated with Alix-2;
DE   AltName: Full=SNF7-1;
DE            Short=hSnf-1;
DE   AltName: Full=Vacuolar protein sorting-associated protein 32-1;
DE            Short=Vps32-1;
DE            Short=hVps32-1;
GN   Name=CHMP4A; Synonyms=C14orf123, SHAX2; ORFNames=CDA04, HSPC134;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProt.
DR   GO; GO:0042802; F:identical protein binding; IMP:UniProt.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0006900; P:membrane budding; IMP:UniProt.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0097320; P:membrane tubulation; IMP:UniProt.
DR   GO; GO:1902902; P:negative regulation of autophagic vacuole assembly; IMP:UniProt.
DR   GO; GO:1901215; P:negative regulation of neuron death; IMP:UniProt.
DR   GO; GO:0006620; P:posttranslational protein targeting to membrane; IMP:UniProt.
DR   GO; GO:0051260; P:protein homooligomerization; IMP:UniProt.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHM4B_HUMAN             Reviewed;         224 AA.
AC   Q9H444; E1P5N4; Q53ZD6;
DE   RecName: Full=Charged multivesicular body protein 4b;
DE   AltName: Full=Chromatin-modifying protein 4b;
DE            Short=CHMP4b;
DE   AltName: Full=SNF7 homolog associated with Alix 1;
DE   AltName: Full=SNF7-2;
DE            Short=hSnf7-2;
DE   AltName: Full=Vacuolar protein sorting-associated protein 32-2;
DE            Short=Vps32-2;
DE            Short=hVps32-2;
GN   Name=CHMP4B; Synonyms=C20orf178, SHAX1;
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:1902902; P:negative regulation of autophagic vacuole assembly; IMP:UniProt.
DR   GO; GO:1901215; P:negative regulation of neuron death; IMP:UniProt.
DR   GO; GO:0006620; P:posttranslational protein targeting to membrane; IMP:UniProt.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProt.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHM4C_HUMAN             Reviewed;         233 AA.
AC   Q96CF2; B2RBZ1;
DE   RecName: Full=Charged multivesicular body protein 4c;
DE   AltName: Full=Chromatin-modifying protein 4c;
DE            Short=CHMP4c;
DE   AltName: Full=SNF7 homolog associated with Alix 3;
DE   AltName: Full=SNF7-3;
DE            Short=hSnf7-3;
DE   AltName: Full=Vacuolar protein sorting-associated protein 32-3;
DE            Short=Vps32-3;
DE            Short=hVps32-3;
GN   Name=CHMP4C; Synonyms=SHAX3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHM4P_HUMAN             Reviewed;         171 AA.
AC   P59074; Q8NFA9;
DE   RecName: Full=Putative charged multivesicular body protein 4B-like protein CHMP4BP1;
DE   AltName: Full=Charged multivesicular body protein 4B pseudogene 1;
GN   Name=CHMP4BP1; ORFNames=CGI-301;
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
//
ID   CHMP3_HUMAN             Reviewed;         222 AA.
AC   Q9Y3E7; A8K3W0; B4DG34; B8ZZM0; B8ZZX5; Q3ZTS9; Q53S71; Q53SU5;
AC   Q9NZ51;
DE   RecName: Full=Charged multivesicular body protein 3;
DE   AltName: Full=Chromatin-modifying protein 3;
DE   AltName: Full=Neuroendocrine differentiation factor;
DE   AltName: Full=Vacuolar protein sorting-associated protein 24;
DE            Short=hVps24;
GN   Name=CHMP3; Synonyms=CGI149, NEDF, VPS24; ORFNames=CGI-149;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHMP5_HUMAN             Reviewed;         219 AA.
AC   Q9NZZ3; B2RD95; B4DIR6; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9Y323;
DE   RecName: Full=Charged multivesicular body protein 5;
DE   AltName: Full=Chromatin-modifying protein 5;
DE   AltName: Full=SNF7 domain-containing protein 2;
DE   AltName: Full=Vacuolar protein sorting-associated protein 60;
DE            Short=Vps60;
DE            Short=hVps60;
GN   Name=CHMP5; Synonyms=C9orf83, SNF7DC2;
GN   ORFNames=CGI-34, HSPC177, PNAS-114, PNAS-2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0001919; P:regulation of receptor recycling; IEA:Ensembl.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHMP6_HUMAN             Reviewed;         201 AA.
AC   Q96FZ7; A8K7U0; Q53FU4; Q9HAE8;
DE   RecName: Full=Charged multivesicular body protein 6;
DE   AltName: Full=Chromatin-modifying protein 6;
DE   AltName: Full=Vacuolar protein sorting-associated protein 20;
DE            Short=Vps20;
DE            Short=hVps20;
GN   Name=CHMP6; Synonyms=VPS20;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHMP7_HUMAN             Reviewed;         453 AA.
AC   Q8WUX9; B2RDT3; D3DSS1; Q8NDM1; Q9BT50;
DE   RecName: Full=Charged multivesicular body protein 7;
DE   AltName: Full=Chromatin-modifying protein 7;
GN   Name=CHMP7;
DR   GO; GO:0008565; F:protein transporter activity; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0045324; P:late endosome to vacuole transport; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CHODL_HUMAN             Reviewed;         273 AA.
AC   Q9H9P2; B2R9C0; B4DJB8; Q7Z798; Q7Z799; Q7Z7A0; Q9HCY3;
DE   RecName: Full=Chondrolectin;
DE   AltName: Full=Transmembrane protein MT75;
DE   Flags: Precursor;
GN   Name=CHODL; Synonyms=C21orf68; ORFNames=PRED12, UNQ872/PRO1890;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0007517; P:muscle organ development; NAS:HGNC.
//
ID   CHP1_HUMAN              Reviewed;         195 AA.
AC   Q99653; B2R6H9; Q6FHZ9;
DE   RecName: Full=Calcineurin B homologous protein 1;
DE   AltName: Full=Calcineurin B-like protein;
DE   AltName: Full=Calcium-binding protein CHP;
DE   AltName: Full=Calcium-binding protein p22;
DE   AltName: Full=EF-hand calcium-binding domain-containing protein p22;
GN   Name=CHP1; Synonyms=CHP;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; ISS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; ISS:UniProtKB.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0071468; P:cellular response to acidity; ISS:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; ISS:UniProtKB.
DR   GO; GO:0022406; P:membrane docking; ISS:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; ISS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; ISS:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.
DR   GO; GO:0070885; P:negative regulation of calcineurin-NFAT signaling cascade; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0060050; P:positive regulation of protein glycosylation; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0051222; P:positive regulation of protein transport; ISS:UniProtKB.
DR   GO; GO:0032417; P:positive regulation of sodium:proton antiporter activity; IDA:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0006611; P:protein export from nucleus; ISS:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0051453; P:regulation of intracellular pH; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0045056; P:transcytosis; IEA:Ensembl.
//
ID   CHP2_HUMAN              Reviewed;         196 AA.
AC   O43745; A8K2I8;
DE   RecName: Full=Calcineurin B homologous protein 2;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 520;
GN   Name=CHP2; Synonyms=HCA520;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010922; P:positive regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   CHP3_HUMAN              Reviewed;         214 AA.
AC   Q96BS2; F5H1Y5; Q9NWT9;
DE   RecName: Full=Calcineurin B homologous protein 3;
DE   AltName: Full=Tescalcin;
DE            Short=TSC;
GN   Name=TESC; Synonyms=CHP3;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0019212; F:phosphatase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0030219; P:megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0032417; P:positive regulation of sodium:proton antiporter activity; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0051604; P:protein maturation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.
//
ID   CHPF2_HUMAN             Reviewed;         772 AA.
AC   Q9P2E5; B2DBD8; Q6P2I4; Q6UXD2;
DE   RecName: Full=Chondroitin sulfate glucuronyltransferase;
DE            EC=2.4.1.226;
DE   AltName: Full=CSGlcA-T;
DE   AltName: Full=Chondroitin glucuronyltransferase;
DE   AltName: Full=Chondroitin polymerizing factor 2;
DE            Short=ChPF-2;
DE   AltName: Full=Chondroitin synthase 3;
DE            Short=ChSy-3;
DE   AltName: Full=N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase;
GN   Name=CHPF2; Synonyms=CHSY3, CSGLCAT, KIAA1402; ORFNames=UNQ299/PRO339;
DR   GO; GO:0050510; F:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHPT1_HUMAN             Reviewed;         406 AA.
AC   Q8WUD6; B3KQM2; Q7Z7H0; Q7Z7H1; Q7Z7H2; Q8IWQ4; Q8IWQ5; Q8WYI4;
AC   Q9NRQ6; Q9NRQ7; Q9Y6M6;
DE   RecName: Full=Cholinephosphotransferase 1;
DE            Short=hCPT1;
DE            EC=2.7.8.2;
DE   AltName: Full=AAPT1-like protein;
DE   AltName: Full=Diacylglycerol cholinephosphotransferase 1;
GN   Name=CHPT1; Synonyms=CPT1; ORFNames=MSTP022;
DR   GO; GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.
DR   GO; GO:0004142; F:diacylglycerol cholinephosphotransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006657; P:CDP-choline pathway; NAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006663; P:platelet activating factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHRC1_HUMAN             Reviewed;         131 AA.
AC   Q9NRG0;
DE   RecName: Full=Chromatin accessibility complex protein 1;
DE            Short=CHRAC-1;
DE   AltName: Full=Chromatin accessibility complex 15 kDa protein;
DE            Short=CHRAC-15;
DE            Short=HuCHRAC15;
DE   AltName: Full=DNA polymerase epsilon subunit p15;
GN   Name=CHRAC1; Synonyms=CHRAC15;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; NAS:GOC.
//
ID   CHRD1_HUMAN             Reviewed;         332 AA.
AC   Q9UHD1; B2R6P8; Q6IN49; Q8WVL9; Q9H3D6;
DE   RecName: Full=Cysteine and histidine-rich domain-containing protein 1;
DE   AltName: Full=CHORD domain-containing protein 1;
DE            Short=CHORD-containing protein 1;
DE            Short=CHP-1;
DE   AltName: Full=Protein morgana;
GN   Name=CHORDC1; Synonyms=CHP1;
DR   GO; GO:0051879; F:Hsp90 protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; ISS:UniProtKB.
DR   GO; GO:2000299; P:negative regulation of Rho-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:1900034; P:regulation of cellular response to heat; ISS:UniProtKB.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   CHRD_HUMAN              Reviewed;         955 AA.
AC   Q9H2X0; O95254; Q2M1I8; Q6UW83; Q9H2D3; Q9H2W8; Q9H2W9; Q9P0Z2;
AC   Q9P0Z3; Q9P0Z4; Q9P0Z5;
DE   RecName: Full=Chordin;
DE   Flags: Precursor;
GN   Name=CHRD; ORFNames=UNQ217/PRO243;
DR   GO; GO:0019955; F:cytokine binding; NAS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0021919; P:BMP signaling pathway involved in spinal cord dorsal/ventral patterning; IMP:BHF-UCL.
DR   GO; GO:0033504; P:floor plate development; TAS:BHF-UCL.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; TAS:UniProtKB.
//
ID   CHSP1_HUMAN             Reviewed;         147 AA.
AC   Q9Y2V2; B2R4C3; D3DUF5; Q2YDX5; Q9BQ53;
DE   RecName: Full=Calcium-regulated heat stable protein 1;
DE   AltName: Full=Calcium-regulated heat-stable protein of 24 kDa;
DE            Short=CRHSP-24;
GN   Name=CARHSP1;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   CHSS1_HUMAN             Reviewed;         802 AA.
AC   Q86X52; Q6UX38; Q7LFU5; Q9Y2J5;
DE   RecName: Full=Chondroitin sulfate synthase 1;
DE            EC=2.4.1.175;
DE            EC=2.4.1.226;
DE   AltName: Full=Chondroitin glucuronyltransferase 1;
DE   AltName: Full=Chondroitin synthase 1;
DE            Short=ChSy-1;
DE   AltName: Full=Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1;
DE   AltName: Full=N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1;
DE   AltName: Full=N-acetylgalactosaminyltransferase 1;
GN   Name=CHSY1; Synonyms=CHSY, CSS1, KIAA0990; ORFNames=UNQ756/PRO1487;
DR   GO; GO:0047238; F:glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050510; F:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:MGI.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030279; P:negative regulation of ossification; IMP:UniProtKB.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHSS2_HUMAN             Reviewed;         775 AA.
AC   Q8IZ52; B4DXU0; Q6UXD6; Q7L4G1; Q9H0F8; Q9H618;
DE   RecName: Full=Chondroitin sulfate synthase 2;
DE            EC=2.4.1.175;
DE            EC=2.4.1.226;
DE   AltName: Full=Chondroitin glucuronyltransferase 2;
DE   AltName: Full=Chondroitin-polymerizing factor;
DE            Short=ChPF;
DE   AltName: Full=Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II;
DE   AltName: Full=N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II;
DE   AltName: Full=N-acetylgalactosaminyltransferase 2;
GN   Name=CHPF; Synonyms=CSS2; ORFNames=UNQ651/PRO1281;
DR   GO; GO:0047238; F:glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050510; F:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHSS3_HUMAN             Reviewed;         882 AA.
AC   Q70JA7; B2RP97; Q76L22; Q86Y52;
DE   RecName: Full=Chondroitin sulfate synthase 3;
DE            EC=2.4.1.175;
DE            EC=2.4.1.226;
DE   AltName: Full=Carbohydrate synthase 2;
DE   AltName: Full=Chondroitin glucuronyltransferase 3;
DE   AltName: Full=Chondroitin synthase 2;
DE            Short=ChSy-2;
DE   AltName: Full=Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II;
DE   AltName: Full=N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3;
DE   AltName: Full=N-acetylgalactosaminyltransferase 3;
GN   Name=CHSY3; Synonyms=CHSY2, CSS3;
DR   GO; GO:0047238; F:glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050510; F:N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHST1_HUMAN             Reviewed;         411 AA.
AC   O43916; D3DQP2;
DE   RecName: Full=Carbohydrate sulfotransferase 1;
DE            EC=2.8.2.21;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1;
DE            Short=GST-1;
DE   AltName: Full=Keratan sulfate Gal-6 sulfotransferase;
DE            Short=KS6ST;
DE            Short=KSGal6ST;
DE            Short=KSST;
GN   Name=CHST1;
DR   GO; GO:0045130; F:keratan sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008146; F:sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006012; P:galactose metabolic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; IDA:UniProtKB.
DR   GO; GO:0005976; P:polysaccharide metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST2_HUMAN             Reviewed;         530 AA.
AC   Q9Y4C5; D3DNG5; Q2M370; Q9GZN5; Q9UED5; Q9Y6F2;
DE   RecName: Full=Carbohydrate sulfotransferase 2;
DE            EC=2.8.2.-;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2;
DE            Short=GST-2;
DE   AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 1;
DE            Short=GlcNAc6ST-1;
DE            Short=Gn6ST-1;
GN   Name=CHST2; Synonyms=GN6ST;
DR   GO; GO:0001517; F:N-acetylglucosamine 6-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST3_HUMAN             Reviewed;         479 AA.
AC   Q7LGC8; O75099; Q52M30;
DE   RecName: Full=Carbohydrate sulfotransferase 3;
DE            EC=2.8.2.17;
DE   AltName: Full=Chondroitin 6-O-sulfotransferase 1;
DE            Short=C6ST-1;
DE   AltName: Full=Chondroitin 6-sulfotransferase;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0;
DE            Short=GST-0;
GN   Name=CHST3;
DR   GO; GO:0008459; F:chondroitin 6-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0050698; F:proteoglycan sulfotransferase activity; IEA:Ensembl.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
//
ID   CHST4_HUMAN             Reviewed;         386 AA.
AC   Q8NCG5; Q8IV46; Q9Y5R3;
DE   RecName: Full=Carbohydrate sulfotransferase 4;
DE            EC=2.8.2.-;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3;
DE            Short=GST-3;
DE   AltName: Full=High endothelial cells N-acetylglucosamine 6-O-sulfotransferase;
DE            Short=HEC-GlcNAc6ST;
DE   AltName: Full=L-selectin ligand sulfotransferase;
DE            Short=LSST;
DE   AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 2;
DE            Short=GlcNAc6ST-2;
DE            Short=Gn6st-2;
GN   Name=CHST4;
DR   GO; GO:0001517; F:N-acetylglucosamine 6-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IEA:Ensembl.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006477; P:protein sulfation; TAS:ProtInc.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST5_HUMAN             Reviewed;         411 AA.
AC   Q9GZS9; B2RV23; Q7LCN3; Q9UBY3;
DE   RecName: Full=Carbohydrate sulfotransferase 5;
DE            EC=2.8.2.-;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha;
DE            Short=GST4-alpha;
DE   AltName: Full=Intestinal N-acetylglucosamine-6-O-sulfotransferase;
DE            Short=I-GlcNAc6ST;
DE            Short=Intestinal GlcNAc-6-sulfotransferase;
DE            Short=hIGn6ST;
DE   AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 3;
DE            Short=GlcNAc6ST-3;
DE            Short=Gn6st-3;
GN   Name=CHST5;
DR   GO; GO:0001517; F:N-acetylglucosamine 6-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006477; P:protein sulfation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST6_HUMAN             Reviewed;         395 AA.
AC   Q9GZX3; D3DUK3;
DE   RecName: Full=Carbohydrate sulfotransferase 6;
DE            EC=2.8.2.-;
DE   AltName: Full=Corneal N-acetylglucosamine-6-O-sulfotransferase;
DE            Short=C-GlcNAc6ST;
DE            Short=hCGn6ST;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta;
DE            Short=GST4-beta;
DE   AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 5;
DE            Short=GlcNAc6ST-5;
DE            Short=Gn6st-5;
GN   Name=CHST6;
DR   GO; GO:0001517; F:N-acetylglucosamine 6-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST7_HUMAN             Reviewed;         486 AA.
AC   Q9NS84; O75667;
DE   RecName: Full=Carbohydrate sulfotransferase 7;
DE            EC=2.8.2.-;
DE            EC=2.8.2.17;
DE   AltName: Full=Chondroitin 6-sulfotransferase 2;
DE            Short=C6ST-2;
DE   AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5;
DE            Short=GST-5;
DE   AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 4;
DE            Short=GlcNAc6ST-4;
DE            Short=Gn6st-4;
GN   Name=CHST7;
DR   GO; GO:0008459; F:chondroitin 6-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0001517; F:N-acetylglucosamine 6-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0005976; P:polysaccharide metabolic process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST8_HUMAN             Reviewed;         424 AA.
AC   Q9H2A9; Q9H3N2;
DE   RecName: Full=Carbohydrate sulfotransferase 8;
DE            EC=2.8.2.-;
DE   AltName: Full=GalNAc-4-O-sulfotransferase 1;
DE            Short=GalNAc-4-ST1;
DE            Short=GalNAc4ST-1;
DE   AltName: Full=N-acetylgalactosamine-4-O-sulfotransferase 1;
GN   Name=CHST8;
DR   GO; GO:0001537; F:N-acetylgalactosamine 4-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEP:UniProtKB.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHST9_HUMAN             Reviewed;         443 AA.
AC   Q7L1S5; Q6UX69; Q9BXH3; Q9BXH4; Q9BZW9;
DE   RecName: Full=Carbohydrate sulfotransferase 9;
DE            EC=2.8.2.-;
DE   AltName: Full=GalNAc-4-O-sulfotransferase 2;
DE            Short=GalNAc-4-ST2;
DE            Short=GalNAc4ST-2;
DE   AltName: Full=N-acetylgalactosamine-4-O-sulfotransferase 2;
GN   Name=CHST9; ORFNames=UNQ2549/PRO6175;
DR   GO; GO:0001537; F:N-acetylgalactosamine 4-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; NAS:UniProtKB.
DR   GO; GO:0042446; P:hormone biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IDA:UniProtKB.
//
ID   CHSTA_HUMAN             Reviewed;         356 AA.
AC   O43529; Q53T18;
DE   RecName: Full=Carbohydrate sulfotransferase 10;
DE            EC=2.8.2.-;
DE   AltName: Full=HNK-1 sulfotransferase;
DE            Short=HNK-1ST;
DE            Short=HNK1ST;
DE            Short=HuHNK-1ST;
GN   Name=CHST10;
DR   GO; GO:0016232; F:HNK-1 sulfotransferase activity; IEA:Ensembl.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
//
ID   CHSTC_HUMAN             Reviewed;         414 AA.
AC   Q9NRB3; A4D1Z9; Q502W3; Q9NXY7;
DE   RecName: Full=Carbohydrate sulfotransferase 12;
DE            EC=2.8.2.5;
DE   AltName: Full=Chondroitin 4-O-sulfotransferase 2;
DE   AltName: Full=Chondroitin 4-sulfotransferase 2;
DE            Short=C4ST-2;
DE            Short=C4ST2;
DE   AltName: Full=Sulfotransferase Hlo;
GN   Name=CHST12; ORFNames=UNQ500/PRO1017;
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; NAS:UniProtKB.
DR   GO; GO:0047756; F:chondroitin 4-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHSTB_HUMAN             Reviewed;         352 AA.
AC   Q9NPF2; A8K4F8; Q9NXY6; Q9NY36;
DE   RecName: Full=Carbohydrate sulfotransferase 11;
DE            EC=2.8.2.5;
DE   AltName: Full=Chondroitin 4-O-sulfotransferase 1;
DE   AltName: Full=Chondroitin 4-sulfotransferase 1;
DE            Short=C4S-1;
DE            Short=C4ST-1;
DE            Short=C4ST1;
GN   Name=CHST11;
DR   GO; GO:0047756; F:chondroitin 4-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0001537; F:N-acetylgalactosamine 4-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0050659; F:N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; IEA:Ensembl.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0033037; P:polysaccharide localization; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHSTD_HUMAN             Reviewed;         341 AA.
AC   Q8NET6;
DE   RecName: Full=Carbohydrate sulfotransferase 13;
DE            EC=2.8.2.5;
DE   AltName: Full=Chondroitin 4-O-sulfotransferase 3;
DE   AltName: Full=Chondroitin 4-sulfotransferase 3;
DE            Short=C4ST-3;
DE            Short=C4ST3;
GN   Name=CHST13;
DR   GO; GO:0047756; F:chondroitin 4-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0001537; F:N-acetylgalactosamine 4-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHSTE_HUMAN             Reviewed;         376 AA.
AC   Q8NCH0; Q6PJ31; Q6UXA0; Q96P94;
DE   RecName: Full=Carbohydrate sulfotransferase 14;
DE            EC=2.8.2.35;
DE   AltName: Full=Dermatan 4-sulfotransferase 1;
DE            Short=D4ST-1;
DE            Short=hD4ST1;
GN   Name=CHST14; Synonyms=D4ST1; ORFNames=UNQ1925/PRO4400;
DR   GO; GO:0001537; F:N-acetylgalactosamine 4-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0042301; F:phosphate ion binding; NAS:UniProtKB.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050655; P:dermatan sulfate proteoglycan metabolic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHSTF_HUMAN             Reviewed;         561 AA.
AC   Q7LFX5; O60338; O60474; Q86VM4;
DE   RecName: Full=Carbohydrate sulfotransferase 15;
DE            EC=2.8.2.33;
DE   AltName: Full=B-cell RAG-associated gene protein;
DE            Short=hBRAG;
DE   AltName: Full=N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase;
DE            Short=GalNAc4S-6ST;
GN   Name=CHST15; Synonyms=BRAG, GALNAC4S6ST, KIAA0598;
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; IDA:UniProtKB.
DR   GO; GO:0050659; F:N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0019319; P:hexose biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CHTOP_HUMAN             Reviewed;         248 AA.
AC   Q9Y3Y2; D3DV55; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4;
AC   Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0;
DE   RecName: Full=Chromatin target of PRMT1 protein;
DE   AltName: Full=Friend of PRMT1 protein;
DE   AltName: Full=Small arginine- and glycine-rich protein;
DE            Short=SRAG;
GN   Name=CHTOP; Synonyms=C1orf77, FOP; ORFNames=HT031, PP7704;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CHUR_HUMAN              Reviewed;         139 AA.
AC   Q8WUH1; B3KQ81; G3V1X3; G3V214; Q9H3K7;
DE   RecName: Full=Protein Churchill;
GN   Name=CHURC1; Synonyms=C14orf52, CHCH; ORFNames=My015;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CI009_HUMAN             Reviewed;         222 AA.
AC   Q96E40; Q9UGQ0;
DE   RecName: Full=Uncharacterized protein C9orf9;
GN   Name=C9orf9;
//
ID   CI014_HUMAN             Reviewed;         101 AA.
AC   P0C843;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00032;
GN   Name=LINC00032; Synonyms=C9orf14, NCRNA00032;
//
ID   CI016_HUMAN             Reviewed;          83 AA.
AC   Q9BUW7; Q5SYV8; Q9Y3F7;
DE   RecName: Full=UPF0184 protein C9orf16;
GN   Name=C9orf16; ORFNames=EST00098;
//
ID   CI027_HUMAN             Reviewed;          69 AA.
AC   Q9P2X8; Q08EI2;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00474;
DE   AltName: Full=Protein EST-YD1;
GN   Name=LINC00474; Synonyms=C9orf27;
//
ID   CI037_HUMAN             Reviewed;         176 AA.
AC   Q9H2J1; Q17RM5; Q5T368;
DE   RecName: Full=Uncharacterized protein C9orf37;
GN   Name=C9orf37; ORFNames=AD038;
//
ID   CI040_HUMAN             Reviewed;         194 AA.
AC   Q8IXQ3; Q9NWD3;
DE   RecName: Full=Uncharacterized protein C9orf40;
GN   Name=C9orf40;
//
ID   CI038_HUMAN             Reviewed;         118 AA.
AC   Q9UI66;
DE   RecName: Full=Uncharacterized protein C9orf38;
GN   Name=C9orf38; ORFNames=PRO0365;
//
ID   CI041_HUMAN             Reviewed;         409 AA.
AC   Q8N4J0; Q7Z383; Q8N7C5;
DE   RecName: Full=UPF0586 protein C9orf41;
GN   Name=C9orf41;
//
ID   CI043_HUMAN             Reviewed;         461 AA.
AC   Q8TAL5;
DE   RecName: Full=Uncharacterized protein C9orf43;
GN   Name=C9orf43;
//
ID   CI047_HUMAN             Reviewed;         202 AA.
AC   Q6ZRZ4; B7ZMC7; Q5SQD7; Q7Z568; Q8N1V4;
DE   RecName: Full=Uncharacterized protein C9orf47;
DE   Flags: Precursor;
GN   Name=C9orf47; Synonyms=C9orf108;
//
ID   CI050_HUMAN             Reviewed;         431 AA.
AC   Q5SZB4; Q2M1I2; Q8NA65;
DE   RecName: Full=Uncharacterized protein C9orf50;
GN   Name=C9orf50;
//
ID   CI057_HUMAN             Reviewed;         161 AA.
AC   Q5W0N0;
DE   RecName: Full=Uncharacterized protein C9orf57;
GN   Name=C9orf57;
//
ID   CI062_HUMAN             Reviewed;         152 AA.
AC   Q8N4C0; Q5T7E2;
DE   RecName: Full=Putative uncharacterized protein C9orf62;
GN   Name=C9orf62;
//
ID   CI064_HUMAN             Reviewed;         341 AA.
AC   Q5T6V5; B2RPI6; Q8N2B1; Q9BT18;
DE   RecName: Full=UPF0553 protein C9orf64;
GN   Name=C9orf64;
//
ID   CI069_HUMAN             Reviewed;         139 AA.
AC   H0YL14;
DE   RecName: Full=Protein C9orf69;
DE   AltName: Full=Herpes virus UL25-binding protein;
GN   Name=C9orf69;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0048524; P:positive regulation of viral process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CI066_HUMAN             Reviewed;         295 AA.
AC   Q5T8R8; Q96NB0;
DE   RecName: Full=Uncharacterized protein C9orf66;
GN   Name=C9orf66;
//
ID   CI072_HUMAN             Reviewed;         481 AA.
AC   Q96LT7; A8K5W0; D3DRK6; G8I0B6; Q6NUS9;
DE   RecName: Full=Protein C9orf72;
GN   Name=C9orf72;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
//
ID   CI078_HUMAN             Reviewed;         289 AA.
AC   Q9NZ63; B3KPX8; Q8WVU6; Q9NT39;
DE   RecName: Full=Uncharacterized protein C9orf78;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 59;
GN   Name=C9orf78; Synonyms=HCA59;
//
ID   CI085_HUMAN             Reviewed;         179 AA.
AC   Q96MD7; Q5W0N1; Q5W0N3; Q6PJW9; Q86U95;
DE   RecName: Full=Uncharacterized protein C9orf85;
GN   Name=C9orf85;
//
ID   CI084_HUMAN             Reviewed;        1444 AA.
AC   Q5VXU9; A2A2V3; Q2M1H8; Q96M73;
DE   RecName: Full=Uncharacterized protein C9orf84;
GN   Name=C9orf84;
//
ID   CI091_HUMAN             Reviewed;         342 AA.
AC   Q5VZI3; A0PJA3; Q3KNS4; Q5VZI2; Q6P5Z7; Q8N1P3; Q8ND43;
DE   RecName: Full=Transmembrane protein C9orf91;
GN   Name=C9orf91;
//
ID   CI107_HUMAN             Reviewed;          73 AA.
AC   B1AMM8;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00587;
GN   Name=LINC00587; Synonyms=C9orf107;
//
ID   CI106_HUMAN             Reviewed;         232 AA.
AC   Q8NAJ2;
DE   RecName: Full=Putative uncharacterized protein C9orf106;
GN   Name=C9orf106;
//
ID   CI092_HUMAN             Reviewed;          77 AA.
AC   A6NGG3; A6NMF8;
DE   RecName: Full=Putative uncharacterized protein C9orf92;
GN   Name=C9orf92;
//
ID   CI114_HUMAN             Reviewed;         376 AA.
AC   Q5T280; Q0D2P6; Q6P469; Q6PGP9; Q6PIJ1; Q6PJV9;
DE   RecName: Full=Uncharacterized protein C9orf114;
GN   Name=C9orf114;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CI116_HUMAN             Reviewed;         136 AA.
AC   Q5BN46; Q5T897; Q8WU44;
DE   RecName: Full=UPF0691 protein C9orf116;
DE   AltName: Full=p53-induced expression in RB-null cells protein 1;
DE            Short=Pierce1;
GN   Name=C9orf116;
//
ID   CI118_HUMAN             Reviewed;          69 AA.
AC   A6NHY6;
DE   RecName: Full=Putative uncharacterized protein C9orf118;
GN   Name=C9orf118;
//
ID   CI129_HUMAN             Reviewed;         196 AA.
AC   Q5T035;
DE   RecName: Full=Putative uncharacterized protein C9orf129;
GN   Name=C9orf129;
//
ID   CI130_HUMAN             Reviewed;         136 AA.
AC   Q8WZB0;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00476;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 12 protein;
GN   Name=LINC00476; Synonyms=C9orf130; ORFNames=NAG12;
//
ID   CI117_HUMAN             Reviewed;         520 AA.
AC   Q5JU67; A5D8T9;
DE   RecName: Full=Uncharacterized protein C9orf117;
GN   Name=C9orf117;
//
ID   CI131_HUMAN             Reviewed;        1079 AA.
AC   Q5VYM1; A6NLE6; E9PB26; Q86XC6; Q9UF74;
DE   RecName: Full=Uncharacterized protein C9orf131;
GN   Name=C9orf131;
//
ID   CI139_HUMAN             Reviewed;         190 AA.
AC   Q6ZV77; A2RUA3; B9EGW2; Q5SPY0; Q8N224;
DE   RecName: Full=Uncharacterized protein C9orf139;
GN   Name=C9orf139;
//
ID   CI142_HUMAN             Reviewed;         204 AA.
AC   Q9BUH6; Q8IY19;
DE   RecName: Full=Uncharacterized protein C9orf142;
GN   Name=C9orf142;
//
ID   CI135_HUMAN             Reviewed;         229 AA.
AC   Q5VTT2; B2RN61;
DE   RecName: Full=Uncharacterized protein C9orf135;
GN   Name=C9orf135;
//
ID   CI152_HUMAN             Reviewed;         239 AA.
AC   Q5JTZ5; A8MWT6;
DE   RecName: Full=Uncharacterized protein C9orf152;
GN   Name=C9orf152;
//
ID   CI153_HUMAN             Reviewed;         101 AA.
AC   Q5TBE3; Q5TBE4;
DE   RecName: Full=Uncharacterized protein C9orf153;
GN   Name=C9orf153;
//
ID   CI163_HUMAN             Reviewed;         203 AA.
AC   Q8N9P6;
DE   RecName: Full=Uncharacterized protein C9orf163;
GN   Name=C9orf163;
//
ID   CI169_HUMAN             Reviewed;         144 AA.
AC   A8MQ03; Q86UY7;
DE   RecName: Full=UPF0574 protein C9orf169;
GN   Name=C9orf169;
//
ID   CI170_HUMAN             Reviewed;         121 AA.
AC   A2RU37;
DE   RecName: Full=Uncharacterized protein C9orf170;
GN   Name=C9orf170;
//
ID   CI171_HUMAN             Reviewed;         320 AA.
AC   Q6ZQR2; Q147X1;
DE   RecName: Full=Uncharacterized protein C9orf171;
GN   Name=C9orf171;
//
ID   CI172_HUMAN             Reviewed;         976 AA.
AC   C9J069;
DE   RecName: Full=Uncharacterized protein C9orf172;
GN   Name=C9orf172;
//
ID   CI173_HUMAN             Reviewed;         389 AA.
AC   Q8N7X2; A2RU24; B7ZM72; B7ZM76; Q8NEA3;
DE   RecName: Full=Uncharacterized protein C9orf173;
GN   Name=C9orf173;
//
ID   CIA30_HUMAN             Reviewed;         327 AA.
AC   Q9Y375; Q9BVZ5;
DE   RecName: Full=Complex I intermediate-associated protein 30, mitochondrial;
DE   AltName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1;
DE   Flags: Precursor;
GN   Name=NDUFAF1; Synonyms=CIA30; ORFNames=CGI-65;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
//
ID   CIAO1_HUMAN             Reviewed;         339 AA.
AC   O76071; A0MNN9; Q53FM5;
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein CIAO1;
DE   AltName: Full=WD repeat-containing protein 39;
GN   Name=CIAO1; Synonyms=WDR39;
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IGI:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CIART_HUMAN             Reviewed;         385 AA.
AC   Q8N365; B2RD43; D3DV01; Q8N795; Q96MG6;
DE   RecName: Full=Circadian-associated transcriptional repressor;
DE   AltName: Full=ChIP-derived repressor of network oscillator;
DE            Short=Chrono;
DE   AltName: Full=Computationally highlighted repressor of the network oscillator;
GN   Name=CIART; Synonyms=C1orf51;
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CIB3_HUMAN              Reviewed;         187 AA.
AC   Q96Q77; Q2M1W0;
DE   RecName: Full=Calcium and integrin-binding family member 3;
DE   AltName: Full=Kinase-interacting protein 3;
DE            Short=KIP 3;
GN   Name=CIB3; Synonyms=KIP3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CIB4_HUMAN              Reviewed;         185 AA.
AC   A0PJX0; B2RU18;
DE   RecName: Full=Calcium and integrin-binding family member 4;
GN   Name=CIB4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CIB2_HUMAN              Reviewed;         187 AA.
AC   O75838; B4DDF0; H0YM71; Q05BT6;
DE   RecName: Full=Calcium and integrin-binding family member 2;
DE   AltName: Full=Kinase-interacting protein 2;
DE            Short=KIP 2;
GN   Name=CIB2; Synonyms=KIP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0055074; P:calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:UniProtKB.
//
ID   CIB1_HUMAN              Reviewed;         191 AA.
AC   Q99828; B5BU40; H6WJF3; O00693; O00735; Q6IB49; Q96J54; Q99971;
DE   RecName: Full=Calcium and integrin-binding protein 1;
DE            Short=CIB;
DE   AltName: Full=Calcium- and integrin-binding protein;
DE            Short=CIBP;
DE   AltName: Full=Calmyrin;
DE   AltName: Full=DNA-PKcs-interacting protein;
DE   AltName: Full=Kinase-interacting protein;
DE            Short=KIP;
DE   AltName: Full=SNK-interacting protein 2-28;
DE            Short=SIP2-28;
GN   Name=CIB1; Synonyms=CIB, KIP, PRKDCIP;
DR   GO; GO:0005509; F:calcium ion binding; IMP:HGNC.
DR   GO; GO:0043495; F:protein anchor; IGI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IMP:HGNC.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:HGNC.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IMP:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; TAS:ProtInc.
DR   GO; GO:0007113; P:endomitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045653; P:negative regulation of megakaryocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0030220; P:platelet formation; ISS:UniProtKB.
DR   GO; GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IDA:BHF-UCL.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IGI:BHF-UCL.
DR   GO; GO:1901313; P:positive regulation of gene expression involved in extracellular matrix organization; ISS:UniProtKB.
DR   GO; GO:2000256; P:positive regulation of male germ cell proliferation; ISS:UniProtKB.
DR   GO; GO:0048554; P:positive regulation of metalloenzyme activity; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0051302; P:regulation of cell division; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
DR   GO; GO:0038163; P:thrombopoietin-mediated signaling pathway; ISS:UniProtKB.
//
ID   CIC_HUMAN               Reviewed;        1608 AA.
AC   Q96RK0; Q7LGI1; Q9UEG5; Q9Y6T1;
DE   RecName: Full=Protein capicua homolog;
GN   Name=CIC; Synonyms=KIAA0306;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CIDEA_HUMAN             Reviewed;         219 AA.
AC   O60543; B0YIY7; Q6UPR7;
DE   RecName: Full=Cell death activator CIDE-A;
DE   AltName: Full=Cell death-inducing DFFA-like effector A;
GN   Name=CIDEA;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; ISS:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0019915; P:lipid storage; ISS:BHF-UCL.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IMP:BHF-UCL.
DR   GO; GO:1900118; P:negative regulation of execution phase of apoptosis; ISS:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IMP:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; ISS:BHF-UCL.
DR   GO; GO:1902510; P:regulation of apoptotic DNA fragmentation; ISS:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CIDEB_HUMAN             Reviewed;         219 AA.
AC   Q9UHD4; D3DS73; Q546V8; Q9NNW9;
DE   RecName: Full=Cell death activator CIDE-B;
DE   AltName: Full=Cell death-inducing DFFA-like effector B;
GN   Name=CIDEB;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:0097194; P:execution phase of apoptosis; ISS:BHF-UCL.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
//
ID   CIDEC_HUMAN             Reviewed;         238 AA.
AC   Q96AQ7; C9JMN7; Q67DW9; Q9GZY9;
DE   RecName: Full=Cell death activator CIDE-3;
DE   AltName: Full=Cell death-inducing DFFA-like effector protein C;
DE   AltName: Full=Fat-specific protein FSP27 homolog;
GN   Name=CIDEC; Synonyms=FSP27;
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0034389; P:lipid particle organization; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CIKS_HUMAN              Reviewed;         574 AA.
AC   O43734; B2RAY9; E1P555; Q5R3A3; Q7Z6Q1; Q7Z6Q2; Q7Z6Q3; Q9H5W2;
AC   Q9H6Y3; Q9NS14; Q9UG72;
DE   RecName: Full=Adapter protein CIKS;
DE   AltName: Full=Connection to IKK and SAPK/JNK;
DE   AltName: Full=Nuclear factor NF-kappa-B activator 1;
DE            Short=ACT1;
DE   AltName: Full=TRAF3-interacting protein 2;
GN   Name=TRAF3IP2; Synonyms=C6orf2, C6orf4, C6orf5, C6orf6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001783; P:B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0048305; P:immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
//
ID   CILP1_HUMAN             Reviewed;        1184 AA.
AC   O75339; B2R8F7; Q6UW99; Q8IYI5;
DE   RecName: Full=Cartilage intermediate layer protein 1;
DE            Short=CILP-1;
DE   AltName: Full=Cartilage intermediate-layer protein;
DE   Contains:
DE     RecName: Full=Cartilage intermediate layer protein 1 C1;
DE   Contains:
DE     RecName: Full=Cartilage intermediate layer protein 1 C2;
DE   Flags: Precursor;
GN   Name=CILP; ORFNames=UNQ602/PRO1188;
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
//
ID   CILP2_HUMAN             Reviewed;        1156 AA.
AC   Q8IUL8; Q6NV88; Q8N4A6; Q8WV21;
DE   RecName: Full=Cartilage intermediate layer protein 2;
DE            Short=CILP-2;
DE   Contains:
DE     RecName: Full=Cartilage intermediate layer protein 2 C1;
DE   Contains:
DE     RecName: Full=Cartilage intermediate layer protein 2 C2;
DE   Flags: Precursor;
GN   Name=CILP2;
//
ID   CING_HUMAN              Reviewed;        1197 AA.
AC   Q9P2M7; A6H8L3; A7MD22; Q5T386; Q9NR25;
DE   RecName: Full=Cingulin;
GN   Name=CGN; Synonyms=KIAA1319;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   CINP_HUMAN              Reviewed;         212 AA.
AC   Q9BW66; F5H7P3; F5H8A7; Q9NPF9;
DE   RecName: Full=Cyclin-dependent kinase 2-interacting protein;
DE            Short=CDK2-interacting protein;
GN   Name=CINP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   CIP1_HUMAN              Reviewed;         277 AA.
AC   Q9NPC3;
DE   RecName: Full=E3 ubiquitin-protein ligase CCNB1IP1;
DE            EC=6.3.2.-;
DE   AltName: Full=Cyclin-B1-interacting protein 1;
DE   AltName: Full=Human enhancer of invasion 10;
GN   Name=CCNB1IP1; Synonyms=C14orf18, HEI10;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001825; P:blastocyst formation; IEA:Ensembl.
DR   GO; GO:0051026; P:chiasma assembly; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   CIP2A_HUMAN             Reviewed;         905 AA.
AC   Q8TCG1; A1L4J7; B9EGC3; Q6P4G6; Q8WVP8; Q96PI2; Q9H9C6; Q9P204;
DE   RecName: Full=Protein CIP2A;
DE   AltName: Full=Cancerous inhibitor of PP2A;
DE   AltName: Full=p90 autoantigen;
GN   Name=KIAA1524; Synonyms=CIP2A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CIP4_HUMAN              Reviewed;         601 AA.
AC   Q15642; B2R8A6; B7WP22; D6W645; O15184; Q53G22; Q5TZN1; Q6FI24;
AC   Q8NFL1; Q8TCY1; Q8TDX3; Q96RJ1;
DE   RecName: Full=Cdc42-interacting protein 4;
DE   AltName: Full=Protein Felic;
DE   AltName: Full=Salt tolerant protein;
DE            Short=hSTP;
DE   AltName: Full=Thyroid receptor-interacting protein 10;
DE            Short=TR-interacting protein 10;
DE            Short=TRIP-10;
GN   Name=TRIP10; Synonyms=CIP4, STOT, STP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0007154; P:cell communication; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   CIPC_HUMAN              Reviewed;         399 AA.
AC   Q9C0C6; B2RCI1; Q8N389; Q8NDZ1;
DE   RecName: Full=CLOCK-interacting pacemaker;
DE   AltName: Full=CLOCK-interacting circadian protein;
GN   Name=CIPC; Synonyms=KIAA1737;
DR   GO; GO:0042754; P:negative regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CIR1A_HUMAN             Reviewed;         686 AA.
AC   Q969X6; Q8NCD9; Q8TF14; Q96SP0; Q96SR9; Q96SZ9; Q96T13; Q9BWK6;
DE   RecName: Full=Cirhin;
GN   Name=CIRH1A; Synonyms=KIAA1988, UTP4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CIR1_HUMAN              Reviewed;         450 AA.
AC   Q86X95; A6NFI6; A8K8M4; O95367; Q12804; Q4G1B9; Q6PJI4; Q8IWI2;
DE   RecName: Full=Corepressor interacting with RBPJ 1;
DE   AltName: Full=CBF1-interacting corepressor;
DE   AltName: Full=Recepin;
GN   Name=CIR1; Synonyms=CIR;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:GOC.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
//
ID   CIRBP_HUMAN             Reviewed;         172 AA.
AC   Q14011;
DE   RecName: Full=Cold-inducible RNA-binding protein;
DE   AltName: Full=A18 hnRNP;
DE   AltName: Full=Glycine-rich RNA-binding protein CIRP;
GN   Name=CIRBP; Synonyms=A18HNRNP, CIRP;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070181; F:SSU rRNA binding; IDA:UniProtKB.
DR   GO; GO:0030371; F:translation repressor activity; ISS:UniProtKB.
DR   GO; GO:0048255; P:mRNA stabilization; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0009409; P:response to cold; TAS:ProtInc.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0034063; P:stress granule assembly; ISS:UniProtKB.
//
ID   CISD1_HUMAN             Reviewed;         108 AA.
AC   Q9NZ45; Q1X902;
DE   RecName: Full=CDGSH iron-sulfur domain-containing protein 1;
DE   AltName: Full=MitoNEET;
GN   Name=CISD1; Synonyms=C10orf70, ZCD1; ORFNames=MDS029;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043457; P:regulation of cellular respiration; IEA:Ensembl.
//
ID   CISD2_HUMAN             Reviewed;         135 AA.
AC   Q8N5K1; Q7Z3D5;
DE   RecName: Full=CDGSH iron-sulfur domain-containing protein 2;
DE   AltName: Full=Endoplasmic reticulum intermembrane small protein;
DE   AltName: Full=MitoNEET-related 1 protein;
DE            Short=Miner1;
DE   AltName: Full=Nutrient-deprivation autophagy factor-1;
DE            Short=NAF-1;
GN   Name=CISD2; Synonyms=CDGSH2, ERIS, ZCD2;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000422; P:mitochondrion degradation; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IMP:UniProtKB.
//
ID   CISD3_HUMAN             Reviewed;         127 AA.
AC   P0C7P0;
DE   RecName: Full=CDGSH iron-sulfur domain-containing protein 3, mitochondrial;
DE   AltName: Full=MitoNEET-related protein 2;
DE            Short=Miner2;
DE   Flags: Precursor;
GN   Name=CISD3;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   CISH_HUMAN              Reviewed;         258 AA.
AC   Q9NSE2; B2R9N1; G5E9R1; Q9NS38; Q9Y5R1;
DE   RecName: Full=Cytokine-inducible SH2-containing protein;
DE            Short=CIS;
DE   AltName: Full=CIS-1;
DE   AltName: Full=Protein G18;
DE   AltName: Full=Suppressor of cytokine signaling;
DE            Short=SOCS;
GN   Name=CISH; Synonyms=G18;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   CISY_HUMAN              Reviewed;         466 AA.
AC   O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8;
DE   RecName: Full=Citrate synthase, mitochondrial;
DE            EC=2.3.3.1;
DE   AltName: Full=Citrate (Si)-synthase;
DE   Flags: Precursor;
GN   Name=CS;
DR   GO; GO:0004108; F:citrate (Si)-synthase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   CITE1_HUMAN             Reviewed;         193 AA.
AC   Q99966; B5BU50; B5BUI2;
DE   RecName: Full=Cbp/p300-interacting transactivator 1;
DE   AltName: Full=Melanocyte-specific protein 1;
GN   Name=CITED1; Synonyms=MSG1;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0050693; F:LBD domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0000578; P:embryonic axis specification; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0042438; P:melanin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; TAS:BHF-UCL.
DR   GO; GO:0001656; P:metanephros development; TAS:BHF-UCL.
DR   GO; GO:0003340; P:negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IDA:UniProtKB.
DR   GO; GO:0043473; P:pigmentation; IMP:UniProtKB.
DR   GO; GO:0001890; P:placenta development; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; ISS:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; ISS:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; ISS:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; ISS:UniProtKB.
DR   GO; GO:0070555; P:response to interleukin-1; ISS:UniProtKB.
DR   GO; GO:0071105; P:response to interleukin-11; ISS:UniProtKB.
DR   GO; GO:0070669; P:response to interleukin-2; ISS:UniProtKB.
DR   GO; GO:0070670; P:response to interleukin-4; ISS:UniProtKB.
DR   GO; GO:0070741; P:response to interleukin-6; ISS:UniProtKB.
DR   GO; GO:0071104; P:response to interleukin-9; ISS:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0071107; P:response to parathyroid hormone; ISS:UniProtKB.
DR   GO; GO:0071559; P:response to transforming growth factor beta; IDA:UniProtKB.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   CITE4_HUMAN             Reviewed;         184 AA.
AC   Q96RK1;
DE   RecName: Full=Cbp/p300-interacting transactivator 4;
DE   AltName: Full=MSG1-related protein 2;
DE            Short=MRG-2;
GN   Name=CITED4; Synonyms=MRG2;
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CITE2_HUMAN             Reviewed;         270 AA.
AC   Q99967; O95426; Q5VTF4;
DE   RecName: Full=Cbp/p300-interacting transactivator 2;
DE   AltName: Full=MSG-related protein 1;
DE            Short=MRG-1;
DE   AltName: Full=P35srj;
GN   Name=CITED2; Synonyms=MRG1;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IDA:BHF-UCL.
DR   GO; GO:0050693; F:LBD domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0061308; P:cardiac neural crest cell development involved in heart development; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0021602; P:cranial nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:UniProtKB.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0060971; P:embryonic heart tube left/right pattern formation; ISS:BHF-UCL.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0003197; P:endocardial cushion development; IEA:Ensembl.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0030851; P:granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0070986; P:left/right axis specification; ISS:BHF-UCL.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; ISS:BHF-UCL.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0061428; P:negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:1900164; P:nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; ISS:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.
DR   GO; GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0061156; P:pulmonary artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0003156; P:regulation of organ formation; ISS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IDA:GOC.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0034405; P:response to fluid shear stress; IMP:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007530; P:sex determination; ISS:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; ISS:BHF-UCL.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   CIZ1_HUMAN              Reviewed;         898 AA.
AC   Q9ULV3; A8K9J8; B4E131; B7ZAS8; Q5SYW3; Q5SYW5; Q8WU72; Q9H868;
AC   Q9NYM8; Q9UHK4; Q9Y3F9; Q9Y3G0;
DE   RecName: Full=Cip1-interacting zinc finger protein;
DE   AltName: Full=CDKN1A-interacting zinc finger protein 1;
DE   AltName: Full=Nuclear protein NP94;
DE   AltName: Full=Zinc finger protein 356;
GN   Name=CIZ1; Synonyms=LSFR1, NP94, ZNF356;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IEA:Ensembl.
DR   GO; GO:0032298; P:positive regulation of DNA-dependent DNA replication initiation; IEA:Ensembl.
//
ID   CJ012_HUMAN             Reviewed;        1247 AA.
AC   Q8N655; Q9H945; Q9Y457;
DE   RecName: Full=Uncharacterized protein C10orf12;
GN   Name=C10orf12;
//
ID   CJ011_HUMAN             Reviewed;         198 AA.
AC   Q9H2I8; B1AVW6;
DE   RecName: Full=Leucine-rich repeat-containing protein C10orf11;
GN   Name=C10orf11; ORFNames=CDA017;
DR   GO; GO:0030318; P:melanocyte differentiation; IMP:UniProtKB.
//
ID   CJ025_HUMAN             Reviewed;         122 AA.
AC   Q5T742; A1L424; Q96NM5;
DE   RecName: Full=Uncharacterized protein C10orf25;
DE   Flags: Precursor;
GN   Name=C10orf25;
//
ID   CJ032_HUMAN             Reviewed;         105 AA.
AC   Q96B45; B2R488; B3KUW4; C9K0X3;
DE   RecName: Full=UPF0693 protein C10orf32;
GN   Name=C10orf32;
//
ID   CJ035_HUMAN             Reviewed;         121 AA.
AC   Q96D05;
DE   RecName: Full=Uncharacterized protein C10orf35;
GN   Name=C10orf35;
//
ID   CJ040_HUMAN             Reviewed;         128 AA.
AC   A4QN01; A6NCD0;
DE   RecName: Full=Putative uncharacterized protein C10orf40;
GN   Name=C10orf40;
//
ID   CJ052_HUMAN             Reviewed;         121 AA.
AC   P0C842;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00614;
GN   Name=LINC00614; Synonyms=C10orf52;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   CJ053_HUMAN             Reviewed;          93 AA.
AC   Q8N6V4; A6NI81; A6NLE0; B9ZVK6;
DE   RecName: Full=UPF0728 protein C10orf53;
GN   Name=C10orf53;
//
ID   CJ055_HUMAN             Reviewed;         151 AA.
AC   Q5SWW7; Q3KRG4; Q8NAK4;
DE   RecName: Full=Uncharacterized protein C10orf55;
GN   Name=C10orf55;
//
ID   CJ062_HUMAN             Reviewed;         223 AA.
AC   Q5T681; Q49A70; Q8N3Y6;
DE   RecName: Full=Uncharacterized protein C10orf62;
GN   Name=C10orf62;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CJ068_HUMAN             Reviewed;         628 AA.
AC   Q9H943; B0QZ71; Q08AN7; Q8N7T7;
DE   RecName: Full=Uncharacterized protein C10orf68;
GN   Name=C10orf68;
//
ID   CJ067_HUMAN             Reviewed;         185 AA.
AC   Q8IYJ2; A8MUP9; Q5SWD4;
DE   RecName: Full=Uncharacterized protein C10orf67;
GN   Name=C10orf67;
//
ID   CJ071_HUMAN             Reviewed;        1435 AA.
AC   Q711Q0; A0AVL8;
DE   RecName: Full=Uncharacterized protein C10orf71;
GN   Name=C10orf71;
//
ID   CJ076_HUMAN             Reviewed;         689 AA.
AC   Q5T2E6; Q2TB87; Q9H8Z9;
DE   RecName: Full=UPF0668 protein C10orf76;
GN   Name=C10orf76;
//
ID   CJ082_HUMAN             Reviewed;         230 AA.
AC   Q8WW14; B3KUM9; D3DRC3;
DE   RecName: Full=Uncharacterized protein C10orf82;
GN   Name=C10orf82;
//
ID   CJ090_HUMAN             Reviewed;         699 AA.
AC   Q96M02; B9EIQ9; Q5JRP6; Q5T023; Q8NCV5; Q8WU75;
DE   RecName: Full=Centrosomal protein C10orf90;
DE   AltName: Full=Fragile-site associated tumor suppressor homolog;
GN   Name=C10orf90; Synonyms=FATS;
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
//
ID   CJ088_HUMAN             Reviewed;         445 AA.
AC   Q9H8K7; Q0P6C6; Q8N597;
DE   RecName: Full=Uncharacterized protein C10orf88;
GN   Name=C10orf88;
//
ID   CJ085_HUMAN             Reviewed;         128 AA.
AC   Q8N1V8;
DE   RecName: Full=Uncharacterized protein C10orf85;
GN   Name=C10orf85;
//
ID   CJ095_HUMAN             Reviewed;         257 AA.
AC   Q9H7T3; A0AVQ7;
DE   RecName: Full=Uncharacterized protein C10orf95;
GN   Name=C10orf95;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CJ099_HUMAN             Reviewed;          81 AA.
AC   Q6UWK7;
DE   RecName: Full=Putative uncharacterized protein C10orf99;
DE   Flags: Precursor;
GN   Name=C10orf99; ORFNames=UNQ1833/PRO3446;
//
ID   CJ107_HUMAN             Reviewed;         208 AA.
AC   Q8IVU9; Q5T1B8;
DE   RecName: Full=Uncharacterized protein C10orf107;
GN   Name=C10orf107;
//
ID   CJ091_HUMAN             Reviewed;         145 AA.
AC   Q5T1B1; Q8N0T7;
DE   RecName: Full=Uncharacterized protein C10orf91;
GN   Name=C10orf91;
//
ID   CJ105_HUMAN             Reviewed;         133 AA.
AC   Q8TEF2;
DE   RecName: Full=Uncharacterized protein C10orf105;
GN   Name=C10orf105;
//
ID   CJ111_HUMAN             Reviewed;         155 AA.
AC   Q8N326; B2RAC4;
DE   RecName: Full=Uncharacterized protein C10orf111;
GN   Name=C10orf111;
//
ID   CJ118_HUMAN             Reviewed;         898 AA.
AC   Q7Z3E2; Q2M2V6; Q3ZB81; Q6NS91; Q7RTP1; Q8N117; Q8N3G3; Q8N6C2;
AC   Q9NWA3;
DE   RecName: Full=Uncharacterized protein C10orf118;
DE   AltName: Full=CTCL tumor antigen HD-CL-01/L14-2;
GN   Name=C10orf118;
//
ID   CJ113_HUMAN             Reviewed;         155 AA.
AC   Q5VZT2; B9EIM9; E9PRX7;
DE   RecName: Full=Putative uncharacterized protein C10orf113;
GN   Name=C10orf113;
//
ID   CJ115_HUMAN             Reviewed;          94 AA.
AC   Q5QP74;
DE   RecName: Full=Putative uncharacterized protein C10orf115;
GN   Name=C10orf115;
//
ID   CJ120_HUMAN             Reviewed;         335 AA.
AC   Q5SQS8; B2RU17;
DE   RecName: Full=Uncharacterized protein C10orf120;
GN   Name=C10orf120;
//
ID   CJ126_HUMAN             Reviewed;         172 AA.
AC   Q8N4M7; Q5T2Z8;
DE   RecName: Full=Putative uncharacterized protein C10orf126;
GN   Name=C10orf126;
//
ID   CJ128_HUMAN             Reviewed;         105 AA.
AC   Q5T292; A6XND2; Q5T289; Q5T291;
DE   RecName: Full=Putative uncharacterized protein C10orf128;
DE   Flags: Precursor;
GN   Name=C10orf128;
//
ID   CJ131_HUMAN             Reviewed;         256 AA.
AC   A6NCD4; B1AMZ2; B4DG41;
DE   RecName: Full=Uncharacterized protein C10orf131;
GN   Name=C10orf131;
//
ID   CK001_HUMAN             Reviewed;         150 AA.
AC   Q9H5F2; Q6I9X7; Q9NQC6;
DE   RecName: Full=UPF0686 protein C11orf1;
GN   Name=C11orf1;
//
ID   CK016_HUMAN             Reviewed;         467 AA.
AC   Q9NQ32; Q53FB2; Q8N6Y9;
DE   RecName: Full=Uncharacterized protein C11orf16;
GN   Name=C11orf16;
//
ID   CK021_HUMAN             Reviewed;         132 AA.
AC   Q9P2W6;
DE   RecName: Full=Uncharacterized protein C11orf21;
GN   Name=C11orf21;
//
ID   CK024_HUMAN             Reviewed;         449 AA.
AC   Q96F05; Q9H2K4;
DE   RecName: Full=Uncharacterized protein C11orf24;
DE   AltName: Full=Protein DM4E3;
DE   Flags: Precursor;
GN   Name=C11orf24; ORFNames=FP2568, UNQ1872/PRO4315;
//
ID   CK035_HUMAN             Reviewed;         634 AA.
AC   Q8IXW0;
DE   RecName: Full=Uncharacterized protein C11orf35;
GN   Name=C11orf35;
//
ID   CK037_HUMAN             Reviewed;         147 AA.
AC   Q96N53; B2RP80;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00167;
GN   Name=LINC00167; Synonyms=C11orf37, NCRNA00167;
//
ID   CK039_HUMAN             Reviewed;         140 AA.
AC   Q6ZSK4;
DE   RecName: Full=Putative uncharacterized protein C11orf39;
GN   Name=C11orf39;
//
ID   CK040_HUMAN             Reviewed;         217 AA.
AC   Q8WZ69;
DE   RecName: Full=Putative uncharacterized protein C11orf40;
DE   AltName: Full=Ro/SSA1-related protein;
GN   Name=C11orf40; Synonyms=NOV1;
//
ID   CK042_HUMAN             Reviewed;         333 AA.
AC   Q8N5U0;
DE   RecName: Full=Uncharacterized protein C11orf42;
GN   Name=C11orf42;
//
ID   CK045_HUMAN             Reviewed;         145 AA.
AC   Q8TAV5; B2RAD0;
DE   RecName: Full=Putative uncharacterized protein C11orf45;
DE   Flags: Precursor;
GN   Name=C11orf45;
//
ID   CK044_HUMAN             Reviewed;         122 AA.
AC   Q8N8P7;
DE   RecName: Full=Uncharacterized protein C11orf44;
DE   Flags: Precursor;
GN   Name=C11orf44;
//
ID   CK048_HUMAN             Reviewed;         289 AA.
AC   Q9BQE6; Q96NA4;
DE   RecName: Full=Uncharacterized protein C11orf48;
GN   Name=C11orf48;
//
ID   CK049_HUMAN             Reviewed;         331 AA.
AC   Q9H6J7; D3DQQ8; E9PAX7; Q7L077; Q96CS8; Q9BQH4; Q9BUW5;
DE   RecName: Full=UPF0705 protein C11orf49;
GN   Name=C11orf49;
//
ID   CK053_HUMAN             Reviewed;         236 AA.
AC   Q8IXP5;
DE   RecName: Full=Uncharacterized protein C11orf53;
GN   Name=C11orf53;
//
ID   CK054_HUMAN             Reviewed;         315 AA.
AC   Q9H0W9; A8K850; Q6FI88; Q6XYB0; Q96EI3; Q96IX1; Q9Y6B4;
DE   RecName: Full=Ester hydrolase C11orf54;
DE            EC=3.1.-.-;
GN   Name=C11orf54; ORFNames=LP4947, PTD012;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:FlyBase.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
//
ID   CK052_HUMAN             Reviewed;         123 AA.
AC   Q96A22;
DE   RecName: Full=Uncharacterized protein C11orf52;
GN   Name=C11orf52;
//
ID   CK055_HUMAN             Reviewed;         121 AA.
AC   Q6ZST8;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00610;
GN   Name=LINC00610; Synonyms=C11orf55;
//
ID   CK057_HUMAN             Reviewed;         292 AA.
AC   Q6ZUT1; Q5RL41; Q6IN53; Q7Z357; Q8N2T3;
DE   RecName: Full=Uncharacterized protein C11orf57;
GN   Name=C11orf57;
//
ID   CK063_HUMAN             Reviewed;         778 AA.
AC   Q6NUN7; A8K6G0; Q96GB5; Q9H5D6;
DE   RecName: Full=Uncharacterized protein C11orf63;
GN   Name=C11orf63;
//
ID   CK065_HUMAN             Reviewed;         313 AA.
AC   Q8NCR3; Q6PCA8;
DE   RecName: Full=Uncharacterized protein C11orf65;
GN   Name=C11orf65;
//
ID   CK068_HUMAN             Reviewed;         251 AA.
AC   Q9H3H3; J3KQG9; Q9BT13;
DE   RecName: Full=UPF0696 protein C11orf68;
DE   AltName: Full=Basophilic leukemia-expressed protein Bles03;
DE   AltName: Full=Protein p5326;
GN   Name=C11orf68; Synonyms=BLES03;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CK070_HUMAN             Reviewed;         267 AA.
AC   Q9BRQ4; E9PJU1;
DE   RecName: Full=Uncharacterized protein C11orf70;
GN   Name=C11orf70;
//
ID   CK071_HUMAN             Reviewed;         123 AA.
AC   Q6IPW1; Q6IAD3; Q9NXX1;
DE   RecName: Full=Uncharacterized protein C11orf71;
GN   Name=C11orf71;
//
ID   CK072_HUMAN             Reviewed;         251 AA.
AC   Q8NBR9;
DE   RecName: Full=Uncharacterized protein C11orf72;
GN   Name=C11orf72;
//
ID   CK074_HUMAN             Reviewed;         221 AA.
AC   Q86VG3; D3DR18; Q96DD6;
DE   RecName: Full=Uncharacterized protein C11orf74;
DE   AltName: Full=Protein HEPIS;
GN   Name=C11orf74;
//
ID   CK080_HUMAN             Reviewed;         677 AA.
AC   Q8N6T0; Q9H677;
DE   RecName: Full=Putative uncharacterized protein C11orf80;
DE   Flags: Precursor;
GN   Name=C11orf80;
//
ID   CK083_HUMAN             Reviewed;          93 AA.
AC   Q6UW78; Q5FVD5;
DE   RecName: Full=UPF0723 protein C11orf83;
DE   Flags: Precursor;
GN   Name=C11orf83; ORFNames=UNQ655/PRO1286;
//
ID   CK084_HUMAN             Reviewed;         381 AA.
AC   Q9BUA3; Q68CV7; Q6PHS2; Q96IH0;
DE   RecName: Full=Uncharacterized protein C11orf84;
GN   Name=C11orf84;
//
ID   CK085_HUMAN             Reviewed;         216 AA.
AC   Q3KP22;
DE   RecName: Full=Uncharacterized protein C11orf85;
GN   Name=C11orf85;
//
ID   CK087_HUMAN             Reviewed;         197 AA.
AC   Q6NUJ2; B4E169;
DE   RecName: Full=Uncharacterized protein C11orf87;
DE   Flags: Precursor;
GN   Name=C11orf87;
//
ID   CK086_HUMAN             Reviewed;         115 AA.
AC   A6NJI1;
DE   RecName: Full=Uncharacterized protein C11orf86;
GN   Name=C11orf86;
//
ID   CK088_HUMAN             Reviewed;         169 AA.
AC   Q6PI97; E9PAN0; Q6ZRL3;
DE   RecName: Full=UPF0722 protein C11orf88;
GN   Name=C11orf88;
//
ID   CK091_HUMAN             Reviewed;         193 AA.
AC   Q3C1V1; Q3C1V2;
DE   RecName: Full=Uncharacterized protein C11orf91;
GN   Name=C11orf91;
//
ID   CK094_HUMAN             Reviewed;          98 AA.
AC   C9JXX5;
DE   RecName: Full=Uncharacterized protein C11orf94;
DE   Flags: Precursor;
GN   Name=C11orf94;
//
ID   CK095_HUMAN             Reviewed;         678 AA.
AC   C9JLR9; A6NLS7; Q3C1V4;
DE   RecName: Full=Uncharacterized protein C11orf95;
GN   Name=C11orf95;
//
ID   CK096_HUMAN             Reviewed;         435 AA.
AC   Q7Z7L8;
DE   RecName: Full=Uncharacterized protein C11orf96;
DE   AltName: Full=Protein Ag2 homolog;
GN   Name=C11orf96; Synonyms=AG2;
//
ID   CK2N1_HUMAN             Reviewed;          78 AA.
AC   Q7Z7J9;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase II inhibitor 1;
DE   AltName: Full=CaMKII inhibitory protein alpha;
DE            Short=CaMKIIN-alpha;
GN   Name=CAMK2N1;
DR   GO; GO:0008427; F:calcium-dependent protein kinase inhibitor activity; IEA:Ensembl.
//
ID   CK2N2_HUMAN             Reviewed;          79 AA.
AC   Q96S95;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase II inhibitor 2;
DE   AltName: Full=CaM-KII inhibitory protein;
DE            Short=CaM-KIIN;
GN   Name=CAMK2N2;
DR   GO; GO:0008427; F:calcium-dependent protein kinase inhibitor activity; IEA:Ensembl.
//
ID   CK5P1_HUMAN             Reviewed;         601 AA.
AC   Q96SZ6; A8K7R0; Q5QP46; Q5QP47; Q5QP48; Q675N4; Q675N5; Q9BVG6;
AC   Q9BWZ5; Q9H859; Q9NZZ9; Q9Y3F0;
DE   RecName: Full=CDK5 regulatory subunit-associated protein 1;
DE   AltName: Full=CDK5 activator-binding protein C42;
GN   Name=CDK5RAP1; Synonyms=C20orf34; ORFNames=CGI-05, HSPC167;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019901; F:protein kinase binding; NAS:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; NAS:UniProtKB.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; NAS:UniProtKB.
DR   GO; GO:0006400; P:tRNA modification; IEA:InterPro.
//
ID   CK5P2_HUMAN             Reviewed;        1893 AA.
AC   Q96SN8; Q5JV18; Q7Z3L4; Q7Z3U1; Q7Z7I6; Q9BSW0; Q9H6J6; Q9HCD9;
AC   Q9NV90; Q9UIW9;
DE   RecName: Full=CDK5 regulatory subunit-associated protein 2;
DE   AltName: Full=CDK5 activator-binding protein C48;
DE   AltName: Full=Centrosome-associated protein 215;
GN   Name=CDK5RAP2; Synonyms=CEP215, KIAA1633;
DR   GO; GO:0005516; F:calmodulin binding; IPI:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046600; P:negative regulation of centriole replication; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; NAS:UniProtKB.
DR   GO; GO:0090231; P:regulation of spindle checkpoint; IDA:UniProtKB.
//
ID   CK5P3_HUMAN             Reviewed;         506 AA.
AC   Q96JB5; D3DTU1; D3DTU2; Q53FA2; Q9H3F8; Q9H8G0; Q9HBR9;
DE   RecName: Full=CDK5 regulatory subunit-associated protein 3;
DE   AltName: Full=CDK5 activator-binding protein C53;
DE   AltName: Full=Protein HSF-27;
GN   Name=CDK5RAP3; Synonyms=IC53; ORFNames=MSTP016, OK/SW-cl.114, PP1553;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; NAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; NAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0071569; P:protein ufmylation; IDA:MGI.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; NAS:UniProtKB.
//
ID   CKAP2_HUMAN             Reviewed;         683 AA.
AC   Q8WWK9; A2BDE0; A5YM58; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q96FH9;
AC   Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4;
DE   RecName: Full=Cytoskeleton-associated protein 2;
DE   AltName: Full=CTCL tumor antigen se20-10;
DE   AltName: Full=Tumor- and microtubule-associated protein;
GN   Name=CKAP2; Synonyms=LB1, TMAP;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000281; P:mitotic cytokinesis; IGI:MGI.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
//
ID   CKAP4_HUMAN             Reviewed;         602 AA.
AC   Q07065; Q504S5; Q53ES6;
DE   RecName: Full=Cytoskeleton-associated protein 4;
DE   AltName: Full=63-kDa cytoskeleton-linking membrane protein;
DE            Short=Climp-63;
DE            Short=p63;
GN   Name=CKAP4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CKAP5_HUMAN             Reviewed;        2032 AA.
AC   Q14008; Q05D70; Q0VAX7; Q0VAX8; Q14668; Q2TA89; Q6NSH4;
DE   RecName: Full=Cytoskeleton-associated protein 5;
DE   AltName: Full=Colonic and hepatic tumor overexpressed gene protein;
DE            Short=Ch-TOG;
GN   Name=CKAP5; Synonyms=KIAA0097;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0051297; P:centrosome organization; IMP:HGNC.
DR   GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IMP:HGNC.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0050658; P:RNA transport; ISS:HGNC.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   CKLF2_HUMAN             Reviewed;         248 AA.
AC   Q8TAZ6; Q5I2A4; Q8N7E5;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 2;
DE   AltName: Full=Chemokine-like factor superfamily member 2;
GN   Name=CMTM2; Synonyms=CKLFSF2;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF1_HUMAN             Reviewed;         169 AA.
AC   Q8IZ96; Q2PPY5; Q6PEV5; Q8IU76; Q8IU83; Q8IU86; Q8IU93; Q8IZ87;
AC   Q8IZ88; Q8IZ89; Q8IZ90; Q8IZ91; Q8IZ92; Q8IZ93; Q8IZ94; Q8IZ95;
AC   Q96JC2; Q96JC3;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 1;
DE   AltName: Full=Chemokine-like factor superfamily member 1;
GN   Name=CMTM1; Synonyms=CKLFSF1;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF3_HUMAN             Reviewed;         182 AA.
AC   Q96MX0; A6NCL9; Q8IUU8; Q8IWQ6; Q8IYE2; Q8IZ39; Q8IZ59;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 3;
DE   AltName: Full=Chemokine-like factor superfamily member 3;
GN   Name=CMTM3; Synonyms=CKLFSF3;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF4_HUMAN             Reviewed;         234 AA.
AC   Q8IZR5; Q52M40; Q8IZR4; Q8IZV1;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 4;
DE   AltName: Full=Chemokine-like factor superfamily member 4;
GN   Name=CMTM4; Synonyms=CKLFSF4;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF5_HUMAN             Reviewed;         223 AA.
AC   Q96DZ9; E9PH91; Q5PY48;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 5;
DE   AltName: Full=Chemokine-like factor superfamily member 5;
GN   Name=CMTM5; Synonyms=CKLFSF5;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF6_HUMAN             Reviewed;         183 AA.
AC   Q9NX76; Q6IAC4;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 6;
DE   AltName: Full=Chemokine-like factor superfamily member 6;
GN   Name=CMTM6; Synonyms=CKLFSF6;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF7_HUMAN             Reviewed;         175 AA.
AC   Q96FZ5; Q5VLK1;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 7;
DE   AltName: Full=Chemokine-like factor superfamily member 7;
GN   Name=CMTM7; Synonyms=CKLFSF7;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF8_HUMAN             Reviewed;         173 AA.
AC   Q8IZV2; A5D6I7; Q8IW01;
DE   RecName: Full=CKLF-like MARVEL transmembrane domain-containing protein 8;
DE   AltName: Full=Chemokine-like factor superfamily member 8;
GN   Name=CMTM8; Synonyms=CKLFSF8;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   CKLF_HUMAN              Reviewed;         152 AA.
AC   Q9UBR5; C9JE38; Q9UHM7; Q9UHN8; Q9UI41;
DE   RecName: Full=Chemokine-like factor;
DE   AltName: Full=C32;
GN   Name=CKLF; Synonyms=CKLF1; ORFNames=HSPC224, UNQ410/PRO772;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048246; P:macrophage chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0032940; P:secretion by cell; IDA:UniProtKB.
//
ID   CKP2L_HUMAN             Reviewed;         745 AA.
AC   Q8IYA6; A8K915; B4DZE3; B7ZAC6; F5H0M5; Q53QF8; Q53RS8; Q8N1J8;
DE   RecName: Full=Cytoskeleton-associated protein 2-like;
DE   AltName: Full=Radial fiber and mitotic spindle protein;
DE            Short=Radmis;
GN   Name=CKAP2L;
//
ID   CKS1_HUMAN              Reviewed;          79 AA.
AC   P61024; P33551;
DE   RecName: Full=Cyclin-dependent kinases regulatory subunit 1;
DE            Short=CKS-1;
GN   Name=CKS1B; Synonyms=CKS1; ORFNames=PNAS-143, PNAS-16;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
//
ID   CKS2_HUMAN              Reviewed;          79 AA.
AC   P33552; Q6FGI9; Q6LET5;
DE   RecName: Full=Cyclin-dependent kinases regulatory subunit 2;
DE            Short=CKS-2;
GN   Name=CKS2;
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007127; P:meiosis I; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007051; P:spindle organization; NAS:UniProtKB.
//
ID   CL004_HUMAN             Reviewed;         552 AA.
AC   Q9NQ89; D3DUQ8; Q6MZH5;
DE   RecName: Full=Uncharacterized protein C12orf4;
GN   Name=C12orf4;
//
ID   CL029_HUMAN             Reviewed;         325 AA.
AC   Q8N999; Q569K5; Q6AWA8; Q6PEK5; Q8IYQ5; Q9NT75;
DE   RecName: Full=Uncharacterized protein C12orf29;
GN   Name=C12orf29;
//
ID   CL033_HUMAN             Reviewed;         182 AA.
AC   Q8N6U2; B3KW01;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00612;
GN   Name=LINC00612; Synonyms=C12orf33;
//
ID   CL036_HUMAN             Reviewed;         138 AA.
AC   Q495D7; Q8N280;
DE   RecName: Full=Putative uncharacterized protein C12orf36;
GN   Name=C12orf36;
//
ID   CL042_HUMAN             Reviewed;         360 AA.
AC   Q96LP6; Q49A64; Q4G0S2;
DE   RecName: Full=Uncharacterized protein C12orf42;
GN   Name=C12orf42;
//
ID   CL037_HUMAN             Reviewed;         132 AA.
AC   Q96LM1;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00615;
GN   Name=LINC00615; Synonyms=C12orf37;
//
ID   CL043_HUMAN             Reviewed;         262 AA.
AC   Q96C57; Q53HF0; Q9H9Z7;
DE   RecName: Full=Uncharacterized protein C12orf43;
GN   Name=C12orf43;
//
ID   CL040_HUMAN             Reviewed;         652 AA.
AC   Q86WS4; B7WNU1; Q8IXY6; Q8N818; V9HW02;
DE   RecName: Full=Uncharacterized protein C12orf40;
GN   Name=C12orf40;
//
ID   CL045_HUMAN             Reviewed;         185 AA.
AC   Q8N5I9;
DE   RecName: Full=Uncharacterized protein C12orf45;
GN   Name=C12orf45;
//
ID   CL049_HUMAN             Reviewed;         205 AA.
AC   Q9H741; Q53GE8;
DE   RecName: Full=UPF0454 protein C12orf49;
DE   Flags: Precursor;
GN   Name=C12orf49;
//
ID   CL050_HUMAN             Reviewed;         414 AA.
AC   Q8NA57; Q6P674;
DE   RecName: Full=Uncharacterized protein C12orf50;
GN   Name=C12orf50;
//
ID   CL054_HUMAN             Reviewed;         127 AA.
AC   Q6X4T0; Q6X4S9; Q8N5S2;
DE   RecName: Full=Uncharacterized protein C12orf54;
GN   Name=C12orf54; ORFNames=HSD-29, HSD-30, HSD29, HSD30;
//
ID   CL055_HUMAN             Reviewed;         812 AA.
AC   Q96N23;
DE   RecName: Full=Uncharacterized protein C12orf55;
GN   Name=C12orf55;
//
ID   CL060_HUMAN             Reviewed;         245 AA.
AC   Q5U649; A8K1M7; Q5XKK8; Q8IXY2;
DE   RecName: Full=Uncharacterized protein C12orf60;
GN   Name=C12orf60;
//
ID   CL056_HUMAN             Reviewed;         622 AA.
AC   Q8IXR9;
DE   RecName: Full=Uncharacterized protein C12orf56;
GN   Name=C12orf56;
//
ID   CL063_HUMAN             Reviewed;        1197 AA.
AC   Q6ZTY8;
DE   RecName: Full=Putative uncharacterized protein C12orf63;
GN   Name=C12orf63;
//
ID   CL061_HUMAN             Reviewed;         131 AA.
AC   Q8N7H1; B2RMN9; Q3ZCV4;
DE   RecName: Full=Putative uncharacterized protein C12orf61;
GN   Name=C12orf61;
//
ID   CL065_HUMAN             Reviewed;         166 AA.
AC   Q9H3J6; Q8WUC6;
DE   RecName: Full=Probable peptide chain release factor C12orf65, mitochondrial;
DE   Flags: Precursor;
GN   Name=C12orf65; ORFNames=My030;
DR   GO; GO:0003747; F:translation release factor activity; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   CL066_HUMAN             Reviewed;         445 AA.
AC   Q96MD2; C9JX54; Q8IYA0;
DE   RecName: Full=UPF0536 protein C12orf66;
GN   Name=C12orf66;
//
ID   CL067_HUMAN             Reviewed;         166 AA.
AC   Q96M19;
DE   RecName: Full=Transmembrane protein LINC00477;
GN   Name=LINC00477; Synonyms=C12orf67;
//
ID   CL071_HUMAN             Reviewed;         269 AA.
AC   A8MTZ7;
DE   RecName: Full=Uncharacterized protein C12orf71;
GN   Name=C12orf71;
//
ID   CL073_HUMAN             Reviewed;          71 AA.
AC   Q69YU5;
DE   RecName: Full=Uncharacterized protein C12orf73;
DE   Flags: Precursor;
GN   Name=C12orf73;
//
ID   CL074_HUMAN             Reviewed;         190 AA.
AC   Q32Q52; F5H4P0;
DE   RecName: Full=Uncharacterized protein C12orf74;
GN   Name=C12orf74;
//
ID   CL076_HUMAN             Reviewed;         135 AA.
AC   Q8N812;
DE   RecName: Full=Uncharacterized protein C12orf76;
GN   Name=C12orf76;
//
ID   CL097_HUMAN             Reviewed;         145 AA.
AC   C9JDV5;
DE   RecName: Full=Putative uncharacterized protein C12orf77;
GN   Name=C12orf77;
//
ID   CL079_HUMAN             Reviewed;         115 AA.
AC   G3V211; F8VRL5; F8VVU4;
DE   RecName: Full=Uncharacterized protein C12orf79;
GN   Name=C12orf79;
//
ID   CL12A_HUMAN             Reviewed;         265 AA.
AC   Q5QGZ9; B2RA16; Q6P4H1; Q6RH77; Q6RH78; Q8TDQ6;
DE   RecName: Full=C-type lectin domain family 12 member A;
DE   AltName: Full=C-type lectin-like molecule 1;
DE            Short=CLL-1;
DE   AltName: Full=Dendritic cell-associated lectin 2;
DE            Short=DCAL-2;
DE   AltName: Full=Myeloid inhibitory C-type lectin-like receptor;
DE            Short=MICL;
GN   Name=CLEC12A; Synonyms=CLL1, DCAL2, MICL;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CL12B_HUMAN             Reviewed;         276 AA.
AC   Q2HXU8; Q6UWF2; Q6ZRG0;
DE   RecName: Full=C-type lectin domain family 12 member B;
DE   AltName: Full=Macrophage antigen H;
GN   Name=CLEC12B; ORFNames=UNQ5782/PRO16089;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CL16A_HUMAN             Reviewed;        1053 AA.
AC   Q2KHT3; O15058; Q6ZTB2;
DE   RecName: Full=Protein CLEC16A;
GN   Name=CLEC16A; Synonyms=KIAA0350;
//
ID   CL17A_HUMAN             Reviewed;         378 AA.
AC   Q6ZS10; A8MX68; B2RTX0; B7ZMM4;
DE   RecName: Full=C-type lectin domain family 17, member A;
DE   AltName: Full=Prolectin;
GN   Name=CLEC17A;
DR   GO; GO:0042806; F:fucose binding; IDA:UniProtKB.
DR   GO; GO:0005537; F:mannose binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   CL18A_HUMAN             Reviewed;         446 AA.
AC   A5D8T8; A8K1G9; Q6DCB3; Q7Z5K9; Q96HH2;
DE   RecName: Full=C-type lectin domain family 18 member A;
DE   AltName: Full=Mannose receptor-like protein 2;
DE   Flags: Precursor;
GN   Name=CLEC18A; Synonyms=MRLP2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CL18B_HUMAN             Reviewed;         455 AA.
AC   Q6UXF7; B4DF90;
DE   RecName: Full=C-type lectin domain family 18 member B;
DE   AltName: Full=Mannose receptor-like protein 1;
DE   Flags: Precursor;
GN   Name=CLEC18B; Synonyms=MRLP1; ORFNames=UNQ306/PRO347;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CL18C_HUMAN             Reviewed;         446 AA.
AC   Q8NCF0; Q8IUW8;
DE   RecName: Full=C-type lectin domain family 18 member C;
DE   AltName: Full=Mannose receptor-like protein 3;
DE   Flags: Precursor;
GN   Name=CLEC18C; Synonyms=MRLP3;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CL19A_HUMAN             Reviewed;         136 AA.
AC   Q6UXS0; Q0VF32;
DE   RecName: Full=C-type lectin domain family 19 member A;
DE   Flags: Precursor;
GN   Name=CLEC19A; ORFNames=UNQ5810/PRO19627;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CL3L1_HUMAN             Reviewed;          93 AA.
AC   P16619; A6NGK6; B2RUX4; Q3B7A8; Q53YA5; Q96I68;
DE   RecName: Full=C-C motif chemokine 3-like 1;
DE   AltName: Full=G0/G1 switch regulatory protein 19-2;
DE   AltName: Full=LD78-beta(1-70);
DE   AltName: Full=PAT 464.2;
DE   AltName: Full=Small-inducible cytokine A3-like 1;
DE   AltName: Full=Tonsillar lymphocyte LD78 beta protein;
DE   Contains:
DE     RecName: Full=LD78-beta(3-70);
DE   Contains:
DE     RecName: Full=LD78-beta(5-70);
DE   Flags: Precursor;
GN   Name=CCL3L1; Synonyms=D17S1718, G0S19-2, SCYA3L1;
GN   and
GN   Name=CCL3L3;
DR   GO; GO:0060326; P:cell chemotaxis; IEA:GOC.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
//
ID   CLAP1_HUMAN             Reviewed;        1538 AA.
AC   Q7Z460; B7ZLX3; O75118; Q2KHQ9; Q5H9P0; Q8N5B8; Q9BQT5;
DE   RecName: Full=CLIP-associating protein 1;
DE   AltName: Full=Cytoplasmic linker-associated protein 1;
DE   AltName: Full=Multiple asters homolog 1;
DE   AltName: Full=Protein Orbit homolog 1;
DE            Short=hOrbit1;
GN   Name=CLASP1; Synonyms=KIAA0622, MAST1;
DR   GO; GO:0043515; F:kinetochore binding; IMP:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051301; P:cell division; IDA:MGI.
DR   GO; GO:0051294; P:establishment of spindle orientation; IDA:MGI.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; NAS:UniProtKB.
DR   GO; GO:0010458; P:exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034453; P:microtubule anchoring; IMP:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IGI:UniProtKB.
DR   GO; GO:0007020; P:microtubule nucleation; IMP:UniProtKB.
DR   GO; GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.
DR   GO; GO:0031111; P:negative regulation of microtubule polymerization or depolymerization; IMP:UniProtKB.
//
ID   CLAP2_HUMAN             Reviewed;        1294 AA.
AC   O75122; Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2;
DE   RecName: Full=CLIP-associating protein 2;
DE   AltName: Full=Cytoplasmic linker-associated protein 2;
DE   AltName: Full=Protein Orbit homolog 2;
DE            Short=hOrbit2;
GN   Name=CLASP2; Synonyms=KIAA0627;
DR   GO; GO:0008107; F:galactoside 2-alpha-L-fucosyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.
DR   GO; GO:0036065; P:fucosylation; NAS:GOC.
DR   GO; GO:0034453; P:microtubule anchoring; IMP:UniProtKB.
DR   GO; GO:0007020; P:microtubule nucleation; IMP:UniProtKB.
DR   GO; GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; NAS:UniProtKB.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IMP:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
//
ID   CLASR_HUMAN             Reviewed;         674 AA.
AC   Q8N2M8; O96026; Q6UW71; Q96DX2;
DE   RecName: Full=CLK4-associating serine/arginine rich protein;
DE   AltName: Full=Splicing factor, arginine/serine-rich 16;
DE   AltName: Full=Suppressor of white-apricot homolog 2;
GN   Name=CLASRP; Synonyms=SFRS16, SWAP2; ORFNames=UNQ2428/PRO4988;
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   CLAT_HUMAN              Reviewed;         748 AA.
AC   P28329; A2BDF4; Q16488; Q9BQ23; Q9BQ35; Q9BQE1;
DE   RecName: Full=Choline O-acetyltransferase;
DE            Short=CHOACTase;
DE            Short=ChAT;
DE            Short=Choline acetylase;
DE            EC=2.3.1.6;
GN   Name=CHAT;
DR   GO; GO:0004102; F:choline O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0007529; P:establishment of synaptic specificity at neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007622; P:rhythmic behavior; IEA:Ensembl.
DR   GO; GO:0043179; P:rhythmic excitation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   CLC10_HUMAN             Reviewed;         316 AA.
AC   Q8IUN9; A8K8J8; Q14538; Q6PIW3;
DE   RecName: Full=C-type lectin domain family 10 member A;
DE   AltName: Full=C-type lectin superfamily member 14;
DE   AltName: Full=Macrophage lectin 2;
DE   AltName: CD_antigen=CD301;
GN   Name=CLEC10A; Synonyms=CLECSF13, CLECSF14, HML;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   CLC11_HUMAN             Reviewed;         323 AA.
AC   Q9Y240; B2RAD4;
DE   RecName: Full=C-type lectin domain family 11 member A;
DE   AltName: Full=C-type lectin superfamily member 3;
DE   AltName: Full=Lymphocyte secreted C-type lectin;
DE   AltName: Full=Stem cell growth factor;
DE   AltName: Full=p47;
DE   Flags: Precursor;
GN   Name=CLEC11A; Synonyms=CLECSF3, LSLCL, SCGF;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
//
ID   CLC14_HUMAN             Reviewed;         490 AA.
AC   Q86T13; Q695G9; Q6PWT6; Q8N5V5;
DE   RecName: Full=C-type lectin domain family 14 member A;
DE   AltName: Full=Epidermal growth factor receptor 5;
DE            Short=EGFR-5;
DE   Flags: Precursor;
GN   Name=CLEC14A; Synonyms=C14orf27, EGFR5; ORFNames=UNQ236/PRO269;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CLC1A_HUMAN             Reviewed;         280 AA.
AC   Q8NC01; Q8IUW7; Q9NZH3;
DE   RecName: Full=C-type lectin domain family 1 member A;
DE   AltName: Full=C-type lectin-like receptor 1;
DE            Short=CLEC-1;
GN   Name=CLEC1A; Synonyms=CLEC1; ORFNames=UNQ569/PRO1131;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
//
ID   CLC1B_HUMAN             Reviewed;         229 AA.
AC   Q9P126; Q6UWX7; Q8NHR6;
DE   RecName: Full=C-type lectin domain family 1 member B;
DE   AltName: Full=C-type lectin-like receptor 2;
DE            Short=CLEC-2;
GN   Name=CLEC1B; Synonyms=CLEC2; ORFNames=UNQ721/PRO1384;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
//
ID   CLC2B_HUMAN             Reviewed;         149 AA.
AC   Q92478; B2R9U1; Q8IZE9; Q9BS74; Q9UQB4;
DE   RecName: Full=C-type lectin domain family 2 member B;
DE   AltName: Full=Activation-induced C-type lectin;
DE   AltName: Full=C-type lectin superfamily member 2;
DE   AltName: Full=IFN-alpha-2b-inducing-related protein 1;
GN   Name=CLEC2B; Synonyms=AICL, CLECSF2, IFNRG1;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
//
ID   CLC2A_HUMAN             Reviewed;         174 AA.
AC   Q6UVW9; A5Y4G5; A9QKS2; A9QKS3;
DE   RecName: Full=C-type lectin domain family 2 member A;
DE   AltName: Full=Keratinocyte-associated C-type lectin;
DE            Short=KACL;
DE   AltName: Full=Proliferation-induced lymphocyte-associated receptor;
DE            Short=PILAR;
GN   Name=CLEC2A; Synonyms=KACL; ORFNames=UNQ5792/PRO19597;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; TAS:UniProtKB.
//
ID   CLC2D_HUMAN             Reviewed;         191 AA.
AC   Q9UHP7; D6CI39; D6CI40; D6CI41; Q6YID5; Q8WUP7; Q9HD37; Q9HD38;
DE   RecName: Full=C-type lectin domain family 2 member D;
DE   AltName: Full=Lectin-like NK cell receptor;
DE   AltName: Full=Lectin-like transcript 1;
DE            Short=LLT-1;
DE   AltName: Full=Osteoclast inhibitory lectin;
GN   Name=CLEC2D; Synonyms=CLAX, LLT1, OCIL;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
//
ID   CLC2L_HUMAN             Reviewed;         214 AA.
AC   P0C7M8;
DE   RecName: Full=C-type lectin domain family 2 member L;
GN   Name=CLEC2L;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   CLC3A_HUMAN             Reviewed;         197 AA.
AC   O75596; B2R8C4; Q3SX91; Q6UXF5;
DE   RecName: Full=C-type lectin domain family 3 member A;
DE   AltName: Full=C-type lectin superfamily member 1;
DE   AltName: Full=Cartilage-derived C-type lectin;
DE   Flags: Precursor;
GN   Name=CLEC3A; Synonyms=CLECSF1; ORFNames=UNQ700/PRO1345;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   CLC4A_HUMAN             Reviewed;         237 AA.
AC   Q9UMR7; Q17R69; Q8WXW9; Q9H2Z9; Q9NS33; Q9UI34;
DE   RecName: Full=C-type lectin domain family 4 member A;
DE   AltName: Full=C-type lectin DDB27;
DE   AltName: Full=C-type lectin superfamily member 6;
DE   AltName: Full=Dendritic cell immunoreceptor;
DE   AltName: Full=Lectin-like immunoreceptor;
GN   Name=CLEC4A; Synonyms=CLECSF6, DCIR, LLIR; ORFNames=HDCGC13P;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   CLC4C_HUMAN             Reviewed;         213 AA.
AC   Q8WTT0; D3DUU3; Q3T1C3; Q6UXS8; Q8WXX8;
DE   RecName: Full=C-type lectin domain family 4 member C;
DE   AltName: Full=Blood dendritic cell antigen 2;
DE            Short=BDCA-2;
DE   AltName: Full=C-type lectin superfamily member 7;
DE   AltName: Full=Dendritic lectin;
DE   AltName: CD_antigen=CD303;
GN   Name=CLEC4C; Synonyms=BDCA2, CLECSF11, CLECSF7, DLEC, HECL;
GN   ORFNames=UNQ9361/PRO34150;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   CLC4E_HUMAN             Reviewed;         219 AA.
AC   Q9ULY5; B2R6Q6;
DE   RecName: Full=C-type lectin domain family 4 member E;
DE   AltName: Full=C-type lectin superfamily member 9;
DE   AltName: Full=Macrophage-inducible C-type lectin;
GN   Name=CLEC4E; Synonyms=CLECSF9, MINCLE; ORFNames=UNQ218/PRO244;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
//
ID   CLC4D_HUMAN             Reviewed;         215 AA.
AC   Q8WXI8; Q8N5J5;
DE   RecName: Full=C-type lectin domain family 4 member D;
DE   AltName: Full=C-type lectin superfamily member 8;
DE   AltName: Full=C-type lectin-like receptor 6;
DE            Short=CLEC-6;
GN   Name=CLEC4D; Synonyms=CLECSF8, MCL;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   CLC4F_HUMAN             Reviewed;         589 AA.
AC   Q8N1N0;
DE   RecName: Full=C-type lectin domain family 4 member F;
DE   AltName: Full=C-type lectin superfamily member 13;
DE            Short=C-type lectin 13;
GN   Name=CLEC4F; Synonyms=CLECSF13;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
//
ID   CLC4G_HUMAN             Reviewed;         293 AA.
AC   Q6UXB4;
DE   RecName: Full=C-type lectin domain family 4 member G;
GN   Name=CLEC4G; ORFNames=UNQ431/PRO792;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CLC4K_HUMAN             Reviewed;         328 AA.
AC   Q9UJ71;
DE   RecName: Full=C-type lectin domain family 4 member K;
DE   AltName: Full=Langerin;
DE   AltName: CD_antigen=CD207;
GN   Name=CD207; Synonyms=CLEC4K;
DR   GO; GO:0030246; F:carbohydrate binding; IDA:UniProtKB.
DR   GO; GO:0005537; F:mannose binding; TAS:ProtInc.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
//
ID   CLC4M_HUMAN             Reviewed;         399 AA.
AC   Q9H2X3; A6NKI4; A8K8B3; Q69F40; Q969M4; Q96QP3; Q96QP4; Q96QP5;
AC   Q96QP6; Q9BXS3; Q9H2Q9; Q9H8F0; Q9Y2A8;
DE   RecName: Full=C-type lectin domain family 4 member M;
DE   AltName: Full=CD209 antigen-like protein 1;
DE   AltName: Full=DC-SIGN-related protein;
DE            Short=DC-SIGNR;
DE   AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 2;
DE            Short=DC-SIGN2;
DE   AltName: Full=Liver/lymph node-specific ICAM-3-grabbing non-integrin;
DE            Short=L-SIGN;
DE   AltName: CD_antigen=CD299;
GN   Name=CLEC4M; Synonyms=CD209L, CD209L1, CD299;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0030369; F:ICAM-3 receptor activity; NAS:UniProtKB.
DR   GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0046790; F:virion binding; TAS:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; NAS:UniProtKB.
DR   GO; GO:0009988; P:cell-cell recognition; TAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:UniProtKB.
DR   GO; GO:0046968; P:peptide antigen transport; NAS:UniProtKB.
DR   GO; GO:0019079; P:viral genome replication; NAS:UniProtKB.
DR   GO; GO:0019062; P:virion attachment to host cell; TAS:UniProtKB.
//
ID   CLC5A_HUMAN             Reviewed;         188 AA.
AC   Q9NY25; Q52M11; Q9UKQ0;
DE   RecName: Full=C-type lectin domain family 5 member A;
DE   AltName: Full=C-type lectin superfamily member 5;
DE   AltName: Full=Myeloid DAP12-associating lectin 1;
DE            Short=MDL-1;
GN   Name=CLEC5A; Synonyms=CLECSF5, MDL1;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0001618; F:virus receptor activity; IDA:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0033033; P:negative regulation of myeloid cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; ISS:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CLC6A_HUMAN             Reviewed;         209 AA.
AC   Q6EIG7; A2RUK3;
DE   RecName: Full=C-type lectin domain family 6 member A;
DE   AltName: Full=C-type lectin superfamily member 10;
DE   AltName: Full=Dendritic cell-associated C-type lectin 2;
DE            Short=DC-associated C-type lectin 2;
DE            Short=Dectin-2;
GN   Name=CLEC6A; Synonyms=CLECSF10, DECTIN2;
DR   GO; GO:0030246; F:carbohydrate binding; ISS:UniProtKB.
DR   GO; GO:0050832; P:defense response to fungus; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; ISS:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
//
ID   CLC7A_HUMAN             Reviewed;         247 AA.
AC   Q9BXN2; B2R861; B7Z494; B7Z5A9; B7Z5B9; Q6IPS7; Q96D32; Q96DR9;
AC   Q96LD3; Q96PA4; Q96PA5; Q96PA6; Q96PA7; Q96PA8; Q9H1K3;
DE   RecName: Full=C-type lectin domain family 7 member A;
DE   AltName: Full=Beta-glucan receptor;
DE   AltName: Full=C-type lectin superfamily member 12;
DE   AltName: Full=Dendritic cell-associated C-type lectin 1;
DE            Short=DC-associated C-type lectin 1;
DE            Short=Dectin-1;
GN   Name=CLEC7A; Synonyms=BGR, CLECSF12, DECTIN1; ORFNames=UNQ539/PRO1082;
DR   GO; GO:0001872; F:(1->3)-beta-D-glucan binding; IEA:Ensembl.
DR   GO; GO:0001874; F:(1->3)-beta-D-glucan receptor activity; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0008329; F:signaling pattern recognition receptor activity; IDA:UniProtKB.
DR   GO; GO:0009756; P:carbohydrate mediated signaling; TAS:UniProtKB.
DR   GO; GO:0008037; P:cell recognition; IDA:UniProtKB.
DR   GO; GO:0002752; P:cell surface pattern recognition receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0071226; P:cellular response to molecule of fungal origin; IEA:Ensembl.
DR   GO; GO:0042832; P:defense response to protozoan; NAS:UniProtKB.
DR   GO; GO:0001879; P:detection of yeast; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0002366; P:leukocyte activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IEA:Ensembl.
DR   GO; GO:0006910; P:phagocytosis, recognition; IDA:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
//
ID   CLC9A_HUMAN             Reviewed;         241 AA.
AC   Q6UXN8; B0ZBM2;
DE   RecName: Full=C-type lectin domain family 9 member A;
GN   Name=CLEC9A; ORFNames=UNQ9341/PRO34046;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:UniProtKB.
//
ID   CLCA1_HUMAN             Reviewed;         914 AA.
AC   A8K7I4; B2RAV5; O95151; Q5TDF4; Q9UNF6; Q9UPC6;
DE   RecName: Full=Calcium-activated chloride channel regulator 1;
DE   AltName: Full=Calcium-activated chloride channel family member 1;
DE            Short=hCLCA1;
DE   AltName: Full=Calcium-activated chloride channel protein 1;
DE            Short=CaCC-1;
DE            Short=hCaCC-1;
DE   Flags: Precursor;
GN   Name=CLCA1; Synonyms=CACC1;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCA2_HUMAN             Reviewed;         943 AA.
AC   Q9UQC9; A8K2T3; Q9Y6N2;
DE   RecName: Full=Calcium-activated chloride channel regulator 2;
DE   AltName: Full=Calcium-activated chloride channel family member 2;
DE            Short=hCLCA2;
DE   AltName: Full=Calcium-activated chloride channel protein 3;
DE            Short=CaCC-3;
DE            Short=hCaCC-3;
DE   Contains:
DE     RecName: Full=Calcium-activated chloride channel regulator 2, 109 kDa form;
DE   Contains:
DE     RecName: Full=Calcium-activated chloride channel regulator 2, 35 kDa form;
DE   Flags: Precursor;
GN   Name=CLCA2; Synonyms=CACC3;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCA3_HUMAN             Reviewed;         262 AA.
AC   Q9Y6N3;
DE   RecName: Full=Calcium-activated chloride channel regulator family member 3;
DE            Short=Calcium-activated chloride channel family member 3;
DE            Short=hCLCA3;
DE   Flags: Precursor;
GN   Name=CLCA3P; Synonyms=CLCA3;
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCA4_HUMAN             Reviewed;         919 AA.
AC   Q14CN2; Q6UX81; Q9UNF7;
DE   RecName: Full=Calcium-activated chloride channel regulator 4;
DE   AltName: Full=Calcium-activated chloride channel family member 4;
DE            Short=hCLCA4;
DE   AltName: Full=Calcium-activated chloride channel protein 2;
DE            Short=CaCC-2;
DE            Short=hCaCC-2;
DE   Contains:
DE     RecName: Full=Calcium-activated chloride channel regulator 4, 110 kDa form;
DE   Contains:
DE     RecName: Full=Calcium-activated chloride channel regulator 4, 30 kDa form;
DE   Flags: Precursor;
GN   Name=CLCA4; Synonyms=CaCC2; ORFNames=UNQ562/PRO1124;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCA_HUMAN              Reviewed;         248 AA.
AC   P09496; A8K4W3; B4DIN1; F5H6N3; Q2XPN5; Q53XZ1;
DE   RecName: Full=Clathrin light chain A;
DE            Short=Lca;
GN   Name=CLTA;
DR   GO; GO:0032050; F:clathrin heavy chain binding; IPI:FlyBase.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
//
ID   CLCB_HUMAN              Reviewed;         229 AA.
AC   P09497; Q53Y37; Q6FHW1;
DE   RecName: Full=Clathrin light chain B;
DE            Short=Lcb;
GN   Name=CLTB;
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   CLCC1_HUMAN             Reviewed;         551 AA.
AC   Q96S66; O94861; Q8WYP8; Q8WYP9; Q9BU25;
DE   RecName: Full=Chloride channel CLIC-like protein 1;
DE   AltName: Full=Mid-1-related chloride channel protein 1;
DE   Flags: Precursor;
GN   Name=CLCC1; Synonyms=KIAA0761, MCLC;
DR   GO; GO:0005254; F:chloride channel activity; IEA:Ensembl.
//
ID   CLCF1_HUMAN             Reviewed;         225 AA.
AC   Q9UBD9; B4DNT4; Q6NZA4;
DE   RecName: Full=Cardiotrophin-like cytokine factor 1;
DE   AltName: Full=B-cell-stimulating factor 3;
DE            Short=BSF-3;
DE   AltName: Full=Novel neurotrophin-1;
DE            Short=NNT-1;
DE   Flags: Precursor;
GN   Name=CLCF1; Synonyms=BSF3, CLC, NNT1;
DR   GO; GO:0005127; F:ciliary neurotrophic factor receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:HGNC.
DR   GO; GO:0030183; P:B cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007259; P:JAK-STAT cascade; ISS:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; ISS:BHF-UCL.
DR   GO; GO:0048295; P:positive regulation of isotype switching to IgE isotypes; ISS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
//
ID   CLCKA_HUMAN             Reviewed;         687 AA.
AC   P51800; B4DPD3; E7EPH6; Q5T5P8; Q5T5Q4; Q7Z6D1; Q86VT1;
DE   RecName: Full=Chloride channel protein ClC-Ka;
DE            Short=Chloride channel Ka;
DE   AltName: Full=ClC-K1;
GN   Name=CLCNKA;
DR   GuidetoPHARMACOLOGY; 700; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0044070; P:regulation of anion transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCKB_HUMAN             Reviewed;         687 AA.
AC   P51801; B3KUY3; Q5T5Q7; Q5T5Q8;
DE   RecName: Full=Chloride channel protein ClC-Kb;
DE            Short=Chloride channel Kb;
DE   AltName: Full=ClC-K2;
GN   Name=CLCNKB;
DR   GuidetoPHARMACOLOGY; 701; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0044070; P:regulation of anion transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCL1_HUMAN             Reviewed;         167 AA.
AC   Q8IZS7;
DE   RecName: Full=C-type lectin-like domain family 1;
DE   AltName: Full=Dendritic cell-associated lectin 1;
DE            Short=DC-associated lectin-1;
DE            Short=DCAL-1;
GN   Name=CLECL1; Synonyms=DCAL1;
//
ID   CLCN1_HUMAN             Reviewed;         988 AA.
AC   P35523; A4D2H5; Q2M202;
DE   RecName: Full=Chloride channel protein 1;
DE            Short=ClC-1;
DE   AltName: Full=Chloride channel protein, skeletal muscle;
GN   Name=CLCN1; Synonyms=CLC1;
DR   GuidetoPHARMACOLOGY; 698; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0019227; P:neuronal action potential propagation; IEA:Ensembl.
DR   GO; GO:0044070; P:regulation of anion transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCN2_HUMAN             Reviewed;         898 AA.
AC   P51788; B4DQT9; B4DZ58; E9PBD9; E9PCD2; O14864; Q6IPA9; Q8WU13;
DE   RecName: Full=Chloride channel protein 2;
DE            Short=ClC-2;
GN   Name=CLCN2;
DR   GuidetoPHARMACOLOGY; 699; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; TAS:ProtInc.
DR   GO; GO:0060689; P:cell differentiation involved in salivary gland development; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0044070; P:regulation of anion transport; TAS:GOC.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCN3_HUMAN             Reviewed;         818 AA.
AC   P51790; B7Z932; B9EGJ9; D3DP34; E9PB97; O14918; Q86Z21;
DE   RecName: Full=H(+)/Cl(-) exchange transporter 3;
DE   AltName: Full=Chloride channel protein 3;
DE            Short=ClC-3;
DE   AltName: Full=Chloride transporter ClC-3;
GN   Name=CLCN3;
DR   GuidetoPHARMACOLOGY; 702; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005254; F:chloride channel activity; TAS:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0048388; P:endosomal lumen acidification; TAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0044070; P:regulation of anion transport; TAS:GOC.
DR   GO; GO:0006885; P:regulation of pH; TAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCN4_HUMAN             Reviewed;         760 AA.
AC   P51793; A1L3U1; B7Z5Z4; Q9UBU1;
DE   RecName: Full=H(+)/Cl(-) exchange transporter 4;
DE   AltName: Full=Chloride channel protein 4;
DE            Short=ClC-4;
DE   AltName: Full=Chloride transporter ClC-4;
GN   Name=CLCN4;
DR   GuidetoPHARMACOLOGY; 703; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005254; F:chloride channel activity; IDA:MGI.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:MGI.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0044070; P:regulation of anion transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCN5_HUMAN             Reviewed;         746 AA.
AC   P51795; A1L475; B3KPN6; Q5JQD5; Q7RTN8;
DE   RecName: Full=H(+)/Cl(-) exchange transporter 5;
DE   AltName: Full=Chloride channel protein 5;
DE            Short=ClC-5;
DE   AltName: Full=Chloride transporter ClC-5;
GN   Name=CLCN5; Synonyms=CLCK2;
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLCN6_HUMAN             Reviewed;         869 AA.
AC   P51797; A8K1T4; B4DGT7; F8W9R3; O60818; O60819; O60820; O60821;
AC   P78520; P78521; Q17R81; Q5SNW2; Q5SNW3; Q5SNX1; Q5SNX2; Q5SNX3;
AC   Q99427; Q99428; Q99429;
DE   RecName: Full=Chloride transport protein 6;
DE   AltName: Full=Chloride channel protein 6;
DE            Short=ClC-6;
GN   Name=CLCN6; Synonyms=KIAA0046;
DR   GuidetoPHARMACOLOGY; 705; -.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; NAS:UniProtKB.
DR   GO; GO:0006884; P:cell volume homeostasis; NAS:UniProtKB.
DR   GO; GO:0006821; P:chloride transport; NAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0044070; P:regulation of anion transport; NAS:GOC.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CLCN7_HUMAN             Reviewed;         805 AA.
AC   P51798; A6NEJ7; A8K5T9; A8K7X1; B3KPN3; E9PDB9; Q9NYX5;
DE   RecName: Full=H(+)/Cl(-) exchange transporter 7;
DE   AltName: Full=Chloride channel 7 alpha subunit;
DE   AltName: Full=Chloride channel protein 7;
DE            Short=ClC-7;
GN   Name=CLCN7;
DR   GuidetoPHARMACOLOGY; 706; -.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLD10_HUMAN             Reviewed;         228 AA.
AC   P78369; Q6IBF9; Q96N78;
DE   RecName: Full=Claudin-10;
DE   AltName: Full=OSP-like protein;
GN   Name=CLDN10;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   CLD11_HUMAN             Reviewed;         207 AA.
AC   O75508; B2R7C1; D3DNQ5; Q5U0P3;
DE   RecName: Full=Claudin-11;
DE   AltName: Full=Oligodendrocyte-specific protein;
GN   Name=CLDN11; Synonyms=OSP, OTM;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008366; P:axon ensheathment; IEA:Ensembl.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CLD12_HUMAN             Reviewed;         244 AA.
AC   P56749; D6W5Q4; Q7LDZ0;
DE   RecName: Full=Claudin-12;
GN   Name=CLDN12;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD14_HUMAN             Reviewed;         239 AA.
AC   O95500;
DE   RecName: Full=Claudin-14;
GN   Name=CLDN14; ORFNames=UNQ777/PRO1571;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD15_HUMAN             Reviewed;         228 AA.
AC   P56746; B3KPB5;
DE   RecName: Full=Claudin-15;
GN   Name=CLDN15;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD16_HUMAN             Reviewed;         305 AA.
AC   Q9Y5I7;
DE   RecName: Full=Claudin-16;
DE   AltName: Full=Paracellin-1;
DE            Short=PCLN-1;
GN   Name=CLDN16; Synonyms=PCLN1;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0006875; P:cellular metal ion homeostasis; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0015693; P:magnesium ion transport; TAS:GOC.
//
ID   CLD17_HUMAN             Reviewed;         224 AA.
AC   P56750; Q3MJB5; Q6UY37;
DE   RecName: Full=Claudin-17;
GN   Name=CLDN17; ORFNames=UNQ758/PRO1489;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD18_HUMAN             Reviewed;         261 AA.
AC   P56856; A5PL21; Q96PH4;
DE   RecName: Full=Claudin-18;
GN   Name=CLDN18; ORFNames=UNQ778/PRO1572;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD19_HUMAN             Reviewed;         224 AA.
AC   Q8N6F1; B7Z5I2; F5H5P9; Q5QT57; Q8N8X0;
DE   RecName: Full=Claudin-19;
GN   Name=CLDN19;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:Ensembl.
DR   GO; GO:0043297; P:apical junction assembly; IEA:Ensembl.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0019227; P:neuronal action potential propagation; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   CLD1_HUMAN              Reviewed;         211 AA.
AC   O95832;
DE   RecName: Full=Claudin-1;
DE   AltName: Full=Senescence-associated epithelial membrane protein;
GN   Name=CLDN1; Synonyms=CLD1, SEMP1; ORFNames=UNQ481/PRO944;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0045216; P:cell-cell junction organization; IMP:MGI.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CLD20_HUMAN             Reviewed;         219 AA.
AC   P56880;
DE   RecName: Full=Claudin-20;
GN   Name=CLDN20;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD22_HUMAN             Reviewed;         220 AA.
AC   Q8N7P3;
DE   RecName: Full=Claudin-22;
GN   Name=CLDN22;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD23_HUMAN             Reviewed;         292 AA.
AC   Q96B33; Q08AJ3;
DE   RecName: Full=Claudin-23;
GN   Name=CLDN23;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLD24_HUMAN             Reviewed;         220 AA.
AC   A6NM45; F5H040;
DE   RecName: Full=Putative claudin-24;
GN   Name=CLDN24;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   CLD25_HUMAN             Reviewed;         229 AA.
AC   C9JDP6;
DE   RecName: Full=Putative claudin-25;
GN   Name=CLDN25;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   CLD2_HUMAN              Reviewed;         230 AA.
AC   P57739; B2R6B9;
DE   RecName: Full=Claudin-2;
DE   AltName: Full=SP82;
GN   Name=CLDN2; ORFNames=PSEC0059, SP82, UNQ705/PRO1356;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
//
ID   CLD3_HUMAN              Reviewed;         220 AA.
AC   O15551;
DE   RecName: Full=Claudin-3;
DE   AltName: Full=Clostridium perfringens enterotoxin receptor 2;
DE            Short=CPE-R 2;
DE            Short=CPE-receptor 2;
DE   AltName: Full=Rat ventral prostate.1 protein homolog;
DE            Short=hRVP1;
GN   Name=CLDN3; Synonyms=C7orf1, CPETR2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   CLD4_HUMAN              Reviewed;         209 AA.
AC   O14493;
DE   RecName: Full=Claudin-4;
DE   AltName: Full=Clostridium perfringens enterotoxin receptor;
DE            Short=CPE-R;
DE            Short=CPE-receptor;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 8 protein;
GN   Name=CLDN4; Synonyms=CPER, CPETR1, WBSCR8;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   CLD5_HUMAN              Reviewed;         218 AA.
AC   O00501; B3KS11; Q53XW2; Q8WUW3;
DE   RecName: Full=Claudin-5;
DE   AltName: Full=Transmembrane protein deleted in VCFS;
DE            Short=TMDVCF;
GN   Name=CLDN5; Synonyms=AWAL, TMVCF;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
//
ID   CLD6_HUMAN              Reviewed;         220 AA.
AC   P56747; B3KQP9; D3DUA5;
DE   RecName: Full=Claudin-6;
DE   AltName: Full=Skullin;
GN   Name=CLDN6; ORFNames=UNQ757/PRO1488;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
//
ID   CLD7_HUMAN              Reviewed;         211 AA.
AC   O95471; B2R9X7; D3DTP0; Q6IPN3; Q7Z4Y7; Q9BVN0;
DE   RecName: Full=Claudin-7;
DE            Short=CLDN-7;
GN   Name=CLDN7; Synonyms=CEPTRL2, CPETRL2;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
//
ID   CLD8_HUMAN              Reviewed;         225 AA.
AC   P56748; D3DSE3; Q53EX7;
DE   RecName: Full=Claudin-8;
GN   Name=CLDN8; ORFNames=UNQ779/PRO1573;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
//
ID   CLD9_HUMAN              Reviewed;         217 AA.
AC   O95484;
DE   RecName: Full=Claudin-9;
GN   Name=CLDN9;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016338; P:calcium-independent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CLDN1_HUMAN             Reviewed;         253 AA.
AC   Q9NY35; B3KQR1; D3DN36; F2Z2D9; Q502Y8; Q6UVX2; Q9BUZ9; Q9NZZ5;
AC   Q9Y4S9;
DE   RecName: Full=Claudin domain-containing protein 1;
DE   AltName: Full=Membrane protein GENX-3745;
GN   Name=CLDND1; Synonyms=C3orf4;
GN   ORFNames=HSPC174, PSEC0054, UNQ2511/PRO6000;
//
ID   CLDN2_HUMAN             Reviewed;         167 AA.
AC   Q8NHS1;
DE   RecName: Full=Claudin domain-containing protein 2;
GN   Name=CLDND2;
//
ID   CLGN_HUMAN              Reviewed;         610 AA.
AC   O14967; B3KS90; D3DNY8;
DE   RecName: Full=Calmegin;
DE   Flags: Precursor;
GN   Name=CLGN;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   CLH1_HUMAN              Reviewed;        1675 AA.
AC   Q00610; D3DU00; Q6N0A0; Q86TF2;
DE   RecName: Full=Clathrin heavy chain 1;
DE   AltName: Full=Clathrin heavy chain on chromosome 17;
DE            Short=CLH-17;
GN   Name=CLTC; Synonyms=CLH17, CLTCL2, KIAA0034;
DR   GO; GO:0032051; F:clathrin light chain binding; IPI:FlyBase.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:1900126; P:negative regulation of hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0031623; P:receptor internalization; IMP:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; IMP:BHF-UCL.
//
ID   CLH2_HUMAN              Reviewed;        1640 AA.
AC   P53675; B7Z7U5; Q14017; Q15808; Q15809;
DE   RecName: Full=Clathrin heavy chain 2;
DE   AltName: Full=Clathrin heavy chain on chromosome 22;
DE            Short=CLH-22;
GN   Name=CLTCL1; Synonyms=CLH22, CLTCL, CLTD;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IDA:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   CLHC1_HUMAN             Reviewed;         586 AA.
AC   Q8NHS4; B2RDV1; Q53R93; Q8N403;
DE   RecName: Full=Clathrin heavy chain linker domain-containing protein 1;
GN   Name=CLHC1; Synonyms=C2orf63;
//
ID   CLIC1_HUMAN             Reviewed;         241 AA.
AC   O00299; Q15089; Q502X1;
DE   RecName: Full=Chloride intracellular channel protein 1;
DE   AltName: Full=Chloride channel ABP;
DE   AltName: Full=Nuclear chloride ion channel 27;
DE            Short=NCC27;
DE   AltName: Full=Regulatory nuclear chloride ion channel protein;
DE            Short=hRNCC;
GN   Name=CLIC1; Synonyms=G6, NCC27;
DR   GO; GO:0005254; F:chloride channel activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:MGI.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   CLIC2_HUMAN             Reviewed;         247 AA.
AC   O15247; A8K9S0; O15174; Q5JT80; Q8TCE3;
DE   RecName: Full=Chloride intracellular channel protein 2;
DE   AltName: Full=XAP121;
GN   Name=CLIC2;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0051099; P:positive regulation of binding; IDA:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IC:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CLIC3_HUMAN             Reviewed;         236 AA.
AC   O95833; Q5SPZ7;
DE   RecName: Full=Chloride intracellular channel protein 3;
GN   Name=CLIC3;
DR   GO; GO:0005254; F:chloride channel activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; IMP:GOC.
DR   GO; GO:0006821; P:chloride transport; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CLIC4_HUMAN             Reviewed;         253 AA.
AC   Q9Y696; Q9UFW9; Q9UQJ6;
DE   RecName: Full=Chloride intracellular channel protein 4;
DE   AltName: Full=Intracellular chloride ion channel protein p64H1;
GN   Name=CLIC4;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IMP:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; NAS:UniProtKB.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; NAS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007035; P:vacuolar acidification; IEA:Ensembl.
//
ID   CLIC5_HUMAN             Reviewed;         410 AA.
AC   Q9NZA1; B3KUF1; Q5T4Z0; Q8NBY3; Q96JT5; Q9BWZ0;
DE   RecName: Full=Chloride intracellular channel protein 5;
GN   Name=CLIC5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
DR   GO; GO:0006821; P:chloride transport; IDA:UniProtKB.
DR   GO; GO:0002024; P:diet induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   CLIC6_HUMAN             Reviewed;         704 AA.
AC   Q96NY7; A8K0U8; Q8IX31;
DE   RecName: Full=Chloride intracellular channel protein 6;
DE   AltName: Full=Parchorin;
GN   Name=CLIC6; Synonyms=CLIC1L;
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
//
ID   CLIP1_HUMAN             Reviewed;        1438 AA.
AC   P30622; A0AVD3; Q17RS4; Q29RG0;
DE   RecName: Full=CAP-Gly domain-containing linker protein 1;
DE   AltName: Full=Cytoplasmic linker protein 1;
DE   AltName: Full=Cytoplasmic linker protein 170 alpha-2;
DE            Short=CLIP-170;
DE   AltName: Full=Reed-Sternberg intermediate filament-associated protein;
DE   AltName: Full=Restin;
GN   Name=CLIP1; Synonyms=CYLN1, RSN;
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   CLIP2_HUMAN             Reviewed;        1046 AA.
AC   Q9UDT6; O14527; O43611;
DE   RecName: Full=CAP-Gly domain-containing linker protein 2;
DE   AltName: Full=Cytoplasmic linker protein 115;
DE            Short=CLIP-115;
DE   AltName: Full=Cytoplasmic linker protein 2;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 3 protein;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 4 protein;
GN   Name=CLIP2; Synonyms=CYLN2, KIAA0291, WBSCR3, WBSCR4, WSCR4;
//
ID   CLIP3_HUMAN             Reviewed;         547 AA.
AC   Q96DZ5; A8K0E4; Q8WWL1; Q96C99; Q9UFT7;
DE   RecName: Full=CAP-Gly domain-containing linker protein 3;
DE   AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein;
DE            Short=CLIP-170-related 59 kDa protein;
DE            Short=CLIPR-59;
GN   Name=CLIP3; Synonyms=CLIPR59;
DR   GO; GO:0035594; F:ganglioside binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; IMP:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0044091; P:membrane biogenesis; IMP:UniProtKB.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IMP:UniProtKB.
DR   GO; GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IMP:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0010828; P:positive regulation of glucose transport; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
//
ID   CLIP4_HUMAN             Reviewed;         705 AA.
AC   Q8N3C7; A0AV10; B2RMQ3; B7Z7N8; Q7Z4U3; Q96BR7; Q96MA5; Q9H7C0;
DE   RecName: Full=CAP-Gly domain-containing linker protein 4;
DE   AltName: Full=Restin-like protein 2;
GN   Name=CLIP4; Synonyms=RSNL2;
//
ID   CLK1_HUMAN              Reviewed;         484 AA.
AC   P49759; B4DFW7; Q0P694; Q8N5V8;
DE   RecName: Full=Dual specificity protein kinase CLK1;
DE            EC=2.7.12.1;
DE   AltName: Full=CDC-like kinase 1;
GN   Name=CLK1; Synonyms=CLK;
DR   GuidetoPHARMACOLOGY; 1990; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB.
//
ID   CLK2_HUMAN              Reviewed;         499 AA.
AC   P49760; B1AVS9; B5MBX6; Q96CQ0;
DE   RecName: Full=Dual specificity protein kinase CLK2;
DE            EC=2.7.12.1;
DE   AltName: Full=CDC-like kinase 2;
GN   Name=CLK2;
DR   GuidetoPHARMACOLOGY; 1991; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   CLK3_HUMAN              Reviewed;         638 AA.
AC   P49761; D3DW59; Q53Y48; Q9BRS3; Q9BUJ7;
DE   RecName: Full=Dual specificity protein kinase CLK3;
DE            EC=2.7.12.1;
DE   AltName: Full=CDC-like kinase 3;
GN   Name=CLK3;
DR   GuidetoPHARMACOLOGY; 1992; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
//
ID   CLK4_HUMAN              Reviewed;         481 AA.
AC   Q9HAZ1;
DE   RecName: Full=Dual specificity protein kinase CLK4;
DE            EC=2.7.12.1;
DE   AltName: Full=CDC-like kinase 4;
GN   Name=CLK4;
DR   GuidetoPHARMACOLOGY; 1993; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB.
//
ID   CLLU1_HUMAN             Reviewed;         121 AA.
AC   Q5K131;
DE   RecName: Full=Chronic lymphocytic leukemia up-regulated protein 1;
GN   Name=CLLU1;
//
ID   CLM1_HUMAN              Reviewed;         290 AA.
AC   Q8TDQ1; B2RCL2; C9JDN3; Q3Y6P0; Q6UX24; Q7Z6A6; Q7Z7I4; Q7Z7I5;
AC   Q8N6D0; Q8NAF5;
DE   RecName: Full=CMRF35-like molecule 1;
DE            Short=CLM-1;
DE   AltName: Full=CD300 antigen-like family member F;
DE   AltName: Full=Immune receptor expressed on myeloid cells 1;
DE            Short=IREM-1;
DE   AltName: Full=Immunoglobulin superfamily member 13;
DE            Short=IgSF13;
DE   AltName: Full=NK inhibitory receptor;
DE   AltName: CD_antigen=CD300f;
DE   Flags: Precursor;
GN   Name=CD300LF; Synonyms=CD300F, CLM1, IGSF13, IREM1, NKIR;
GN   ORFNames=UNQ3105/PRO10111;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   CLM2_HUMAN              Reviewed;         205 AA.
AC   Q496F6; B4DNS1; Q7Z7I3;
DE   RecName: Full=CMRF35-like molecule 2;
DE            Short=CLM-2;
DE   AltName: Full=CD300 antigen-like family member E;
DE   AltName: Full=CMRF35-A5;
DE   AltName: Full=Immune receptor expressed on myeloid cells 2;
DE            Short=IREM-2;
DE   AltName: Full=Polymeric immunoglobulin receptor 2;
DE            Short=PIgR-2;
DE            Short=PIgR2;
DE            Short=Poly-Ig receptor 2;
DE   AltName: CD_antigen=CD300e;
DE   Flags: Precursor;
GN   Name=CD300E; Synonyms=CD300LE, CLM2, CMRF35A5, IREM2;
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   CLM4_HUMAN              Reviewed;         194 AA.
AC   Q6UXZ3;
DE   RecName: Full=CMRF35-like molecule 4;
DE            Short=CLM-4;
DE   AltName: Full=CD300 antigen-like family member D;
DE   AltName: Full=CMRF35-A4;
DE   AltName: CD_antigen=CD300d;
DE   Flags: Precursor;
GN   Name=CD300LD; Synonyms=CD300D, CMRF35A4; ORFNames=UNQ9218/PRO28686;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   CLM6_HUMAN              Reviewed;         224 AA.
AC   Q08708;
DE   RecName: Full=CMRF35-like molecule 6;
DE            Short=CLM-6;
DE   AltName: Full=CD300 antigen-like family member C;
DE   AltName: Full=CMRF35-A1;
DE            Short=CMRF-35;
DE   AltName: Full=Immunoglobulin superfamily member 16;
DE            Short=IgSF16;
DE   AltName: CD_antigen=CD300c;
DE   Flags: Precursor;
GN   Name=CD300C; Synonyms=CMRF35, CMRF35A, CMRF35A1, IGSF16;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   CLM7_HUMAN              Reviewed;         201 AA.
AC   A8K4G0; Q1EG73; Q8IX40; Q8N6D1;
DE   RecName: Full=CMRF35-like molecule 7;
DE            Short=CLM-7;
DE   AltName: Full=CD300 antigen-like family member B;
DE   AltName: Full=CMRF35-A2;
DE   AltName: Full=Immune receptor expressed on myeloid cells 3;
DE            Short=IREM-3;
DE   AltName: Full=Leukocyte mono-Ig-like receptor 5;
DE   AltName: Full=Triggering receptor expressed on myeloid cells 5;
DE            Short=TREM-5;
DE   AltName: CD_antigen=CD300b;
DE   Flags: Precursor;
GN   Name=CD300LB; Synonyms=CD300B, CLM7, CMRF35A2, IREM3, LMIR5, TREM5;
GN   ORFNames=UNQ2530/PRO6029;
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   CLM8_HUMAN              Reviewed;         299 AA.
AC   Q9UGN4; A8MW96; O95100; Q9HD97; Q9P0F3; Q9UBK4; Q9UMS9; Q9UMT0;
DE   RecName: Full=CMRF35-like molecule 8;
DE            Short=CLM-8;
DE   AltName: Full=CD300 antigen-like family member A;
DE   AltName: Full=CMRF-35-H9;
DE            Short=CMRF35-H9;
DE   AltName: Full=CMRF35-H;
DE   AltName: Full=IRC1/IRC2;
DE   AltName: Full=Immunoglobulin superfamily member 12;
DE            Short=IgSF12;
DE   AltName: Full=Inhibitory receptor protein 60;
DE            Short=IRp60;
DE   AltName: Full=NK inhibitory receptor;
DE   AltName: CD_antigen=CD300a;
DE   Flags: Precursor;
GN   Name=CD300A; Synonyms=CMRF35H, IGSF12; ORFNames=HSPC083;
DR   GO; GO:0008429; F:phosphatidylethanolamine binding; IDA:UniProt.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0038023; F:signaling receptor activity; IDA:UniProt.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:1902569; P:negative regulation of activation of JAK2 kinase activity; IDA:UniProt.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProt.
DR   GO; GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProt.
DR   GO; GO:1902567; P:negative regulation of eosinophil activation; IDA:UniProt.
DR   GO; GO:2000417; P:negative regulation of eosinophil migration; IDA:UniProt.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IDA:UniProt.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProt.
DR   GO; GO:0033007; P:negative regulation of mast cell activation involved in immune response; IDA:UniProt.
DR   GO; GO:0043305; P:negative regulation of mast cell degranulation; IDA:UniProt.
DR   GO; GO:1902564; P:negative regulation of neutrophil activation; IDA:UniProt.
DR   GO; GO:0051134; P:negative regulation of NK T cell activation; IDA:UniProt.
DR   GO; GO:0060101; P:negative regulation of phagocytosis, engulfment; IMP:UniProt.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProt.
DR   GO; GO:0050856; P:regulation of T cell receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IDA:GOC.
//
ID   CLM9_HUMAN              Reviewed;         332 AA.
AC   Q6UXG3; B4DNY5; F5H7P9; F8W9M3; Q8IX38; Q8IX39; Q8TA95;
DE   RecName: Full=CMRF35-like molecule 9;
DE            Short=CLM-9;
DE   AltName: Full=CD300 antigen-like family member G;
DE   AltName: Full=Triggering receptor expressed on myeloid cells 4;
DE            Short=TREM-4;
DE   AltName: CD_antigen=CD300g;
DE   Flags: Precursor;
GN   Name=CD300LG; Synonyms=CLM9, TREM4; ORFNames=UNQ422/PRO846;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   CLMN_HUMAN              Reviewed;        1002 AA.
AC   Q96JQ2; B2RAR7; Q9H713; Q9HA23; Q9HA57; Q9UFP4; Q9ULN2;
DE   RecName: Full=Calmin;
DE   AltName: Full=Calponin-like transmembrane domain protein;
GN   Name=CLMN; Synonyms=KIAA1188;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
//
ID   CLMP_HUMAN              Reviewed;         373 AA.
AC   Q9H6B4;
DE   RecName: Full=CXADR-like membrane protein;
DE   AltName: Full=Adipocyte adhesion molecule;
DE   AltName: Full=Coxsackie- and adenovirus receptor-like membrane protein;
DE            Short=CAR-like membrane protein;
DE   Flags: Precursor;
GN   Name=CLMP; Synonyms=ACAM, ASAM; ORFNames=UNQ318/PRO363;
DR   GO; GO:0048565; P:digestive tract development; IMP:UniProtKB.
//
ID   CLN3_HUMAN              Reviewed;         438 AA.
AC   Q13286; B2R7J1; O00668; O95089; Q549S9; Q9UP09; Q9UP11; Q9UP12;
AC   Q9UP13; Q9UP14;
DE   RecName: Full=Battenin;
DE   AltName: Full=Batten disease protein;
DE   AltName: Full=Protein CLN3;
DE   Flags: Precursor;
GN   Name=CLN3; Synonyms=BTS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0001508; P:action potential; ISS:UniProtKB.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0015809; P:arginine transport; IDA:UniProtKB.
DR   GO; GO:0008306; P:associative learning; ISS:UniProtKB.
DR   GO; GO:0000046; P:autophagic vacuole fusion; ISS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; IDA:UniProtKB.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0006681; P:galactosylceramide metabolic process; IMP:UniProtKB.
DR   GO; GO:0001575; P:globoside metabolic process; IMP:UniProtKB.
DR   GO; GO:0006678; P:glucosylceramide metabolic process; IMP:UniProtKB.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007042; P:lysosomal lumen acidification; IMP:UniProtKB.
DR   GO; GO:0035752; P:lysosomal lumen pH elevation; IDA:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; ISS:UniProtKB.
DR   GO; GO:0016236; P:macroautophagy; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:UniProtKB.
DR   GO; GO:0016242; P:negative regulation of macroautophagy; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; ISS:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; ISS:UniProtKB.
DR   GO; GO:0042133; P:neurotransmitter metabolic process; ISS:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0016485; P:protein processing; ISS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0006684; P:sphingomyelin metabolic process; IMP:UniProtKB.
DR   GO; GO:0007034; P:vacuolar transport; IBA:RefGenome.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IMP:UniProtKB.
//
ID   CLN5_HUMAN              Reviewed;         358 AA.
AC   O75503; B3KQK7;
DE   RecName: Full=Ceroid-lipofuscinosis neuronal protein 5;
DE            Short=Protein CLN5;
DE   Flags: Precursor;
GN   Name=CLN5;
DR   GO; GO:0005537; F:mannose binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0070085; P:glycosylation; IDA:UniProtKB.
DR   GO; GO:0007042; P:lysosomal lumen acidification; IMP:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; IEP:UniProtKB.
DR   GO; GO:0042551; P:neuron maturation; NAS:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0006465; P:signal peptide processing; IDA:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   CLN6_HUMAN              Reviewed;         311 AA.
AC   Q9NWW5; A8K560; Q6IAB1; Q96SR0;
DE   RecName: Full=Ceroid-lipofuscinosis neuronal protein 6;
DE            Short=Protein CLN6;
GN   Name=CLN6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044265; P:cellular macromolecule catabolic process; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IMP:UniProtKB.
DR   GO; GO:0001573; P:ganglioside metabolic process; IMP:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; IMP:UniProtKB.
DR   GO; GO:0031987; P:locomotion involved in locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007042; P:lysosomal lumen acidification; IMP:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   CLN8_HUMAN              Reviewed;         286 AA.
AC   Q9UBY8; Q86U71; Q96I95;
DE   RecName: Full=Protein CLN8;
GN   Name=CLN8; Synonyms=C8orf61;
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0001306; P:age-dependent response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044257; P:cellular protein catabolic process; IEA:Ensembl.
DR   GO; GO:0046513; P:ceramide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; IMP:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; IMP:UniProtKB.
DR   GO; GO:0051935; P:L-glutamate uptake involved in synaptic transmission; IEA:Ensembl.
DR   GO; GO:0008610; P:lipid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; NAS:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0007006; P:mitochondrial membrane organization; IEA:Ensembl.
DR   GO; GO:0050881; P:musculoskeletal movement; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045861; P:negative regulation of proteolysis; NAS:UniProtKB.
DR   GO; GO:0051348; P:negative regulation of transferase activity; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0060052; P:neurofilament cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; IMP:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0021523; P:somatic motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   CLNK_HUMAN              Reviewed;         428 AA.
AC   Q7Z7G1; Q05C27; Q9P2U9;
DE   RecName: Full=Cytokine-dependent hematopoietic cell linker;
DE   AltName: Full=Mast cell immunoreceptor signal transducer;
GN   Name=CLNK; Synonyms=MIST;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; NAS:GOC.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   CLOCK_HUMAN             Reviewed;         846 AA.
AC   O15516; A0AV01; A2I2N9; O14516; Q9UIT8;
DE   RecName: Full=Circadian locomoter output cycles protein kaput;
DE            Short=hCLOCK;
DE            EC=2.3.1.48;
DE   AltName: Full=Class E basic helix-loop-helix protein 8;
DE            Short=bHLHe8;
GN   Name=CLOCK; Synonyms=BHLHE8, KIAA0334;
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0016573; P:histone acetylation; IMP:GOC.
DR   GO; GO:0009648; P:photoperiodism; TAS:ProtInc.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0042634; P:regulation of hair cycle; IMP:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:2000074; P:regulation of type B pancreatic cell development; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
//
ID   CLP1L_HUMAN             Reviewed;         538 AA.
AC   Q96KA5; D3DTC1; Q658W6; Q7LG29; Q96AZ0; Q9H3N4;
DE   RecName: Full=Cleft lip and palate transmembrane protein 1-like protein;
DE            Short=CLPTM1-like protein;
DE   AltName: Full=Cisplatin resistance-related protein 9;
DE            Short=CRR9p;
GN   Name=CLPTM1L; Synonyms=CRR9;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   CLP1_HUMAN              Reviewed;         425 AA.
AC   Q92989; B2R7J6; B4DTI8;
DE   RecName: Full=Polyribonucleotide 5'-hydroxyl-kinase Clp1;
DE            EC=2.7.1.78;
DE   AltName: Full=Polyadenylation factor Clp1;
DE   AltName: Full=Polynucleotide kinase Clp1;
DE   AltName: Full=Pre-mRNA cleavage complex II protein Clp1;
GN   Name=CLP1; Synonyms=HEAB;
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0046404; F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051736; F:ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity; IDA:UniProtKB.
DR   GO; GO:0051733; F:polydeoxyribonucleotide kinase activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0035087; P:siRNA loading onto RISC involved in RNA interference; IDA:UniProtKB.
DR   GO; GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; IMP:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IDA:UniProtKB.
//
ID   CLPB_HUMAN              Reviewed;         707 AA.
AC   Q9H078; B4DXJ7; B4DXP7; E7EWN6; F8W7P6; Q8ND11; Q9H8Y0;
DE   RecName: Full=Caseinolytic peptidase B protein homolog;
DE   AltName: Full=Suppressor of potassium transport defect 3;
GN   Name=CLPB; Synonyms=HSP78, SKD3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
//
ID   CLPP_HUMAN              Reviewed;         277 AA.
AC   Q16740; B2R4W5;
DE   RecName: Full=ATP-dependent Clp protease proteolytic subunit, mitochondrial;
DE            EC=3.4.21.92;
DE   AltName: Full=Endopeptidase Clp;
DE   Flags: Precursor;
GN   Name=CLPP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.
//
ID   CLPT1_HUMAN             Reviewed;         669 AA.
AC   O96005; Q53ET6; Q9BSS5;
DE   RecName: Full=Cleft lip and palate transmembrane protein 1;
GN   Name=CLPTM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0033081; P:regulation of T cell differentiation in thymus; ISS:BHF-UCL.
//
ID   CLPX_HUMAN              Reviewed;         633 AA.
AC   O76031; A1L428; A8K8F1; B9EGI8; Q9H4D9;
DE   RecName: Full=ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial;
DE   Flags: Precursor;
GN   Name=CLPX;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016504; F:peptidase activator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0010952; P:positive regulation of peptidase activity; IDA:GOC.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.
//
ID   CLRN1_HUMAN             Reviewed;         232 AA.
AC   P58418; D3DNJ3; E1ACU9; Q8N6A9;
DE   RecName: Full=Clarin-1;
DE   AltName: Full=Usher syndrome type-3 protein;
GN   Name=CLRN1; Synonyms=USH3A;
DR   GO; GO:0007015; P:actin filament organization; IDA:MGI.
DR   GO; GO:0048870; P:cell motility; IDA:MGI.
DR   GO; GO:0050957; P:equilibrioception; IMP:HGNC.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   CLRN3_HUMAN             Reviewed;         226 AA.
AC   Q8NCR9; Q6MZX8;
DE   RecName: Full=Clarin-3;
DE   AltName: Full=Transmembrane protein 12;
DE   AltName: Full=Usher syndrome type-3A-like protein 1;
GN   Name=CLRN3; Synonyms=TMEM12, USH3AL1;
//
ID   CLRN2_HUMAN             Reviewed;         232 AA.
AC   A0PK11;
DE   RecName: Full=Clarin-2;
GN   Name=CLRN2;
//
ID   CLSPN_HUMAN             Reviewed;        1339 AA.
AC   Q9HAW4; A6NFL4; Q1RMC6; Q2KHM3; Q5VYG0; Q6P6H5; Q8IWI1;
DE   RecName: Full=Claspin;
DE            Short=hClaspin;
GN   Name=CLSPN;
DR   GO; GO:0010997; F:anaphase-promoting complex binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0033314; P:mitotic DNA replication checkpoint; IMP:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
//
ID   CLTR1_HUMAN             Reviewed;         337 AA.
AC   Q9Y271; B2R954; D3DTE4; Q5JS94; Q8IV19;
DE   RecName: Full=Cysteinyl leukotriene receptor 1;
DE            Short=CysLTR1;
DE   AltName: Full=Cysteinyl leukotriene D4 receptor;
DE            Short=LTD4 receptor;
DE   AltName: Full=G-protein coupled receptor HG55;
DE   AltName: Full=HMTMF81;
GN   Name=CYSLTR1; Synonyms=CYSLT1;
DR   GuidetoPHARMACOLOGY; 269; -.
DR   GO; GO:0004974; F:leukotriene receptor activity; TAS:ProtInc.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
//
ID   CLTR2_HUMAN             Reviewed;         346 AA.
AC   Q9NS75; Q9HCQ2;
DE   RecName: Full=Cysteinyl leukotriene receptor 2;
DE            Short=CysLTR2;
DE   AltName: Full=G-protein coupled receptor GPCR21;
DE            Short=hGPCR21;
DE   AltName: Full=G-protein coupled receptor HG57;
DE   AltName: Full=HPN321;
GN   Name=CYSLTR2; Synonyms=CYSLT2, CYSLT2R; ORFNames=PSEC0146;
DR   GuidetoPHARMACOLOGY; 270; -.
DR   GO; GO:0001631; F:cysteinyl leukotriene receptor activity; IEA:Ensembl.
DR   GO; GO:0004974; F:leukotriene receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
//
ID   CLU1O_HUMAN             Reviewed;         101 AA.
AC   Q5K130;
DE   RecName: Full=Putative chronic lymphocytic leukemia up-regulated protein 1 opposite strand transcript protein;
GN   Name=CLLU1OS;
//
ID   CLUA1_HUMAN             Reviewed;         413 AA.
AC   Q96AJ1; O75138; Q65ZA3; Q9H8R4; Q9H8T1;
DE   RecName: Full=Clusterin-associated protein 1;
DE   AltName: Full=Qilin;
GN   Name=CLUAP1; Synonyms=KIAA0643;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   CLUL1_HUMAN             Reviewed;         466 AA.
AC   Q15846; A0FDN7;
DE   RecName: Full=Clusterin-like protein 1;
DE   AltName: Full=Retinal-specific clusterin-like protein;
DE   Flags: Precursor;
GN   Name=CLUL1;
DR   GO; GO:0008219; P:cell death; IEA:InterPro.
//
ID   CLUP3_HUMAN             Reviewed;         147 AA.
AC   Q96NS8; Q9BW88;
DE   RecName: Full=Putative protein CLUHP3;
DE   AltName: Full=Clustered mitochondria (cluA/CLU1) homolog pseudogene 3;
DE   AltName: Full=KIAA0664-like protein 3;
GN   Name=CLUHP3; Synonyms=C16orf67, KIAA0664L3;
//
ID   CLUS_HUMAN              Reviewed;         449 AA.
AC   P10909; B2R9Q1; B3KSE6; P11380; P11381; Q2TU75; Q5HYC1; Q7Z5B9;
DE   RecName: Full=Clusterin;
DE   AltName: Full=Aging-associated gene 4 protein;
DE   AltName: Full=Apolipoprotein J;
DE            Short=Apo-J;
DE   AltName: Full=Complement cytolysis inhibitor;
DE            Short=CLI;
DE   AltName: Full=Complement-associated protein SP-40,40;
DE   AltName: Full=Ku70-binding protein 1;
DE   AltName: Full=NA1/NA2;
DE   AltName: Full=Testosterone-repressed prostate message 2;
DE            Short=TRPM-2;
DE   Contains:
DE     RecName: Full=Clusterin beta chain;
DE     AltName: Full=ApoJalpha;
DE     AltName: Full=Complement cytolysis inhibitor a chain;
DE   Contains:
DE     RecName: Full=Clusterin alpha chain;
DE     AltName: Full=ApoJbeta;
DE     AltName: Full=Complement cytolysis inhibitor b chain;
DE   Flags: Precursor;
GN   Name=CLU; Synonyms=APOJ, CLI, KUB1; ORFNames=AAG4;
DR   GO; GO:0051787; F:misfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032286; P:central nervous system myelin maintenance; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:ProtInc.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0097435; P:fibril organization; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0001774; P:microglial cell activation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0061518; P:microglial cell proliferation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:1902430; P:negative regulation of beta-amyloid formation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0032463; P:negative regulation of protein homooligomerization; IMP:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:1901216; P:positive regulation of neuron death; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0017038; P:protein import; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:1900221; P:regulation of beta-amyloid clearance; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:1901214; P:regulation of neuron death; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0009966; P:regulation of signal transduction; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IC:BHF-UCL.
DR   GO; GO:0051788; P:response to misfolded protein; IDA:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0043691; P:reverse cholesterol transport; TAS:BHF-UCL.
//
ID   CLU_HUMAN               Reviewed;        1309 AA.
AC   O75153; Q6AHY2; Q6P3X7; Q6ZUG8; Q8N4U7; Q9BTA3; Q9H979;
DE   RecName: Full=Clustered mitochondria protein homolog;
GN   Name=CLUH; Synonyms=KIAA0664;
DR   GO; GO:0048312; P:intracellular distribution of mitochondria; IEA:InterPro.
//
ID   CLVS1_HUMAN             Reviewed;         354 AA.
AC   Q8IUQ0; B2R7M5; C8UZT3; Q8NB32;
DE   RecName: Full=Clavesin-1;
DE   AltName: Full=Cellular retinaldehyde-binding protein-like;
DE   AltName: Full=Retinaldehyde-binding protein 1-like 1;
GN   Name=CLVS1; Synonyms=CRALBPL, RLBP1L1;
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007040; P:lysosome organization; ISS:UniProtKB.
//
ID   CLVS2_HUMAN             Reviewed;         327 AA.
AC   Q5SYC1; B3KTG5; B4DHL0; C8UZT4; Q5SYC0;
DE   RecName: Full=Clavesin-2;
DE   AltName: Full=Retinaldehyde-binding protein 1-like 2;
GN   Name=CLVS2; Synonyms=C6orf212, C6orf213, RLBP1L2;
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007040; P:lysosome organization; ISS:UniProtKB.
//
ID   CLYBL_HUMAN             Reviewed;         340 AA.
AC   Q8N0X4; Q5W0F7; Q8TDH8;
DE   RecName: Full=Citrate lyase subunit beta-like protein, mitochondrial;
DE            Short=Citrate lyase beta-like;
DE            EC=4.1.-.-;
DE   Flags: Precursor;
GN   Name=CLYBL; Synonyms=CLB;
DR   GO; GO:0008815; F:citrate (pro-3S)-lyase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
//
ID   CM029_HUMAN             Reviewed;         164 AA.
AC   Q8IVM7;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00346;
GN   Name=LINC00346; Synonyms=C13orf29;
//
ID   CMA1_HUMAN              Reviewed;         247 AA.
AC   P23946; B5BUM8; Q16018; Q3SY36; Q9UDH5;
DE   RecName: Full=Chymase;
DE            EC=3.4.21.39;
DE   AltName: Full=Alpha-chymase;
DE   AltName: Full=Mast cell protease I;
DE   Flags: Precursor;
GN   Name=CMA1; Synonyms=CYH, CYM;
DR   GuidetoPHARMACOLOGY; 2340; -.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050720; P:interleukin-1 beta biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0006518; P:peptide metabolic process; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.
//
ID   CMAH_HUMAN              Reviewed;          72 AA.
AC   Q9Y471; O95250; Q5TD41; Q5TD42; Q5TD43; Q5TD44; Q68DC3; Q9UEE7;
DE   RecName: Full=Putative cytidine monophosphate-N-acetylneuraminic acid hydroxylase-like protein;
DE            Short=CMP-NeuAc hydroxylase-like protein;
DE   AltName: Full=Cytidine monophosphate-N-acetylneuraminic acid hydroxylase pseudogene;
GN   Name=CMAHP; Synonyms=CMAH;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
//
ID   CMBL_HUMAN              Reviewed;         245 AA.
AC   Q96DG6; D3DTC7; Q8TED6;
DE   RecName: Full=Carboxymethylenebutenolidase homolog;
DE            EC=3.1.-.-;
GN   Name=CMBL;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   CMC1_HUMAN              Reviewed;         678 AA.
AC   O75746; B3KR64; Q96AM8;
DE   RecName: Full=Calcium-binding mitochondrial carrier protein Aralar1;
DE   AltName: Full=Mitochondrial aspartate glutamate carrier 1;
DE   AltName: Full=Solute carrier family 25 member 12;
GN   Name=SLC25A12; Synonyms=ARALAR1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0015183; F:L-aspartate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015810; P:aspartate transport; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0015813; P:L-glutamate transport; IDA:UniProtKB.
DR   GO; GO:0043490; P:malate-aspartate shuttle; IDA:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   CMC2_HUMAN              Reviewed;         675 AA.
AC   Q9UJS0; O14566; O14575; Q546F9; Q9NZW1; Q9UNI7;
DE   RecName: Full=Calcium-binding mitochondrial carrier protein Aralar2;
DE   AltName: Full=Citrin;
DE   AltName: Full=Mitochondrial aspartate glutamate carrier 2;
DE   AltName: Full=Solute carrier family 25 member 13;
GN   Name=SLC25A13; Synonyms=ARALAR2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0015183; F:L-aspartate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0015810; P:aspartate transport; IDA:UniProtKB.
DR   GO; GO:0006754; P:ATP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0045333; P:cellular respiration; IDA:UniProtKB.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0015813; P:L-glutamate transport; IDA:UniProtKB.
DR   GO; GO:0043490; P:malate-aspartate shuttle; IDA:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   CMC4_HUMAN              Reviewed;          68 AA.
AC   P56277; Q5HYP9;
DE   RecName: Full=Cx9C motif-containing protein 4;
DE   AltName: Full=Mature T-cell proliferation 1 neighbor protein;
DE   AltName: Full=Mature T-cell proliferation-1 type A;
DE            Short=MTCP-1 type A;
DE   AltName: Full=Protein p8 MTCP-1;
DE            Short=p8MTCP1;
GN   Name=CMC4; Synonyms=C6.1B, MTCP1, MTCP1NB;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
//
ID   CMGA_HUMAN              Reviewed;         457 AA.
AC   P10645; B2R9E9; Q53FA8; Q6NR84; Q96E84; Q96GL7; Q9BQB5;
DE   RecName: Full=Chromogranin-A;
DE            Short=CgA;
DE   AltName: Full=Pituitary secretory protein I;
DE            Short=SP-I;
DE   Contains:
DE     RecName: Full=Vasostatin-1;
DE     AltName: Full=Vasostatin I;
DE   Contains:
DE     RecName: Full=Vasostatin-2;
DE     AltName: Full=Vasostatin II;
DE   Contains:
DE     RecName: Full=EA-92;
DE   Contains:
DE     RecName: Full=ES-43;
DE   Contains:
DE     RecName: Full=Pancreastatin;
DE   Contains:
DE     RecName: Full=SS-18;
DE   Contains:
DE     RecName: Full=WA-8;
DE   Contains:
DE     RecName: Full=WE-14;
DE   Contains:
DE     RecName: Full=LF-19;
DE   Contains:
DE     RecName: Full=AL-11;
DE   Contains:
DE     RecName: Full=GV-19;
DE   Contains:
DE     RecName: Full=GR-44;
DE   Contains:
DE     RecName: Full=ER-37;
DE   Flags: Precursor;
GN   Name=CHGA;
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
//
ID   CMIP_HUMAN              Reviewed;         773 AA.
AC   Q8IY22; Q9C0G9;
DE   RecName: Full=C-Maf-inducing protein;
DE            Short=c-Mip;
DE   AltName: Full=Truncated c-Maf-inducing protein;
DE            Short=Tc-Mip;
GN   Name=CMIP; Synonyms=KIAA1694, TCMIP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CMKMT_HUMAN             Reviewed;         323 AA.
AC   Q7Z624; Q4ZG15; Q53SS6; Q8N6P5; Q9H5G8;
DE   RecName: Full=Calmodulin-lysine N-methyltransferase;
DE            Short=CLNMT;
DE            Short=CaM KMT;
DE            EC=2.1.1.60;
GN   Name=CAMKMT; Synonyms=C2orf34, CLNMT;
DR   GO; GO:0018025; F:calmodulin-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
//
ID   CML1_HUMAN              Reviewed;         373 AA.
AC   Q99788; A8K6Y5; O75748; Q3KP37; Q5U0H0; Q99789;
DE   RecName: Full=Chemokine-like receptor 1;
DE   AltName: Full=G-protein coupled receptor ChemR23;
DE   AltName: Full=G-protein coupled receptor DEZ;
GN   Name=CMKLR1; Synonyms=CHEMR23, DEZ;
DR   GuidetoPHARMACOLOGY; 79; -.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; ISS:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IMP:DFLAT.
DR   GO; GO:0050848; P:regulation of calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   CMPK2_HUMAN             Reviewed;         449 AA.
AC   Q5EBM0; A2RUB0; A5D8T2; B7ZM18; Q6ZRU2; Q96AL8;
DE   RecName: Full=UMP-CMP kinase 2, mitochondrial;
DE            EC=2.7.4.14;
DE   AltName: Full=Nucleoside-diphosphate kinase;
DE            EC=2.7.4.6;
DE   Flags: Precursor;
GN   Name=CMPK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004127; F:cytidylate kinase activity; IDA:MGI.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0004798; F:thymidylate kinase activity; IEA:Ensembl.
DR   GO; GO:0033862; F:UMP kinase activity; IDA:MGI.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006227; P:dUDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
//
ID   CMS1_HUMAN              Reviewed;         279 AA.
AC   Q9BQ75; A8K5S7; B4DUM1; E9PHS3;
DE   RecName: Full=Protein CMSS1;
DE   AltName: Full=Cms1 ribosomal small subunit homolog;
GN   Name=CMSS1; Synonyms=C3orf26;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CMTA1_HUMAN             Reviewed;        1673 AA.
AC   Q9Y6Y1; A7MBM4; G3V3Z7; Q5VUE1; Q6V701; Q8WYI3; Q96S92;
DE   RecName: Full=Calmodulin-binding transcription activator 1;
GN   Name=CAMTA1; Synonyms=KIAA0833; ORFNames=MSTP023;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CMTA2_HUMAN             Reviewed;        1202 AA.
AC   O94983; B9EGL0; D3DTL5; E7EWU5; Q7Z6M8; Q8N3V0; Q8NDG4; Q96G17;
DE   RecName: Full=Calmodulin-binding transcription activator 2;
GN   Name=CAMTA2; Synonyms=KIAA0909;
DR   GO; GO:0003682; F:chromatin binding; IDA:MGI.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IGI:MGI.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CMTD1_HUMAN             Reviewed;         262 AA.
AC   Q86VU5; Q8TE79;
DE   RecName: Full=Catechol O-methyltransferase domain-containing protein 1;
DE            EC=2.1.1.-;
GN   Name=COMTD1; ORFNames=UNQ766/PRO1558;
DR   GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
//
ID   CMTR1_HUMAN             Reviewed;         835 AA.
AC   Q8N1G2; A8K949; Q14670; Q96FJ9;
DE   RecName: Full=Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1;
DE            EC=2.1.1.57;
DE   AltName: Full=Cap methyltransferase 1;
DE   AltName: Full=Cap1 2'O-ribose methyltransferase 1;
DE            Short=MTr1;
DE            Short=hMTr1;
DE   AltName: Full=FtsJ methyltransferase domain-containing protein 2;
DE   AltName: Full=Interferon-stimulated gene 95 kDa protein;
DE            Short=ISG95;
GN   Name=CMTR1; Synonyms=FTSJD2, KIAA0082, MTR1;
DR   GO; GO:0004483; F:mRNA (nucleoside-2'-O-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IDA:UniProtKB.
DR   GO; GO:0097309; P:cap1 mRNA methylation; IDA:UniProtKB.
DR   GO; GO:0080009; P:mRNA methylation; IDA:UniProtKB.
//
ID   CMTR2_HUMAN             Reviewed;         770 AA.
AC   Q8IYT2; B2RCD5; D3DWS1; Q8NE77; Q8NFR5; Q9H8Z4; Q9NUS3; Q9NXF5;
DE   RecName: Full=Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2;
DE            EC=2.1.1.296;
DE   AltName: Full=Cap methyltransferase 2;
DE   AltName: Full=Cap2 2'O-ribose methyltransferase 2;
DE            Short=HMTr2;
DE            Short=MTr2;
DE   AltName: Full=FtsJ methyltransferase domain-containing protein 1;
DE   AltName: Full=Protein adrift homolog;
GN   Name=CMTR2; Synonyms=AFT, FTSJD1;
DR   GO; GO:0004483; F:mRNA (nucleoside-2'-O-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IDA:UniProtKB.
DR   GO; GO:0097310; P:cap2 mRNA methylation; IDA:UniProtKB.
//
ID   CMYA5_HUMAN             Reviewed;        4069 AA.
AC   Q8N3K9; A0PJB7; Q05CT4; Q2NKX1; Q2T9G9; Q69YQ8; Q69YQ9; Q6P517;
AC   Q6P5U3; Q7Z4I1; Q86T34; Q86T49; Q8N3S4; Q8N3S7; Q8NAG8; Q9UK88;
DE   RecName: Full=Cardiomyopathy-associated protein 5;
DE   AltName: Full=Dystrobrevin-binding protein 2;
DE   AltName: Full=Genethonin-3;
DE   AltName: Full=Myospryn;
DE   AltName: Full=SPRY domain-containing protein 2;
DE   AltName: Full=Tripartite motif-containing protein 76;
GN   Name=CMYA5; Synonyms=C5orf10, DTNBP2, SPRYD2, TRIM76;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070885; P:negative regulation of calcineurin-NFAT signaling cascade; IEA:Ensembl.
DR   GO; GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IEA:Ensembl.
DR   GO; GO:0014733; P:regulation of skeletal muscle adaptation; IEA:Ensembl.
//
ID   CN023_HUMAN             Reviewed;         167 AA.
AC   Q86U37; A8MT64;
DE   RecName: Full=Uncharacterized protein C14orf23;
GN   Name=C14orf23;
//
ID   CN028_HUMAN             Reviewed;         310 AA.
AC   Q4W4Y0;
DE   RecName: Full=Uncharacterized protein C14orf28;
DE   AltName: Full=Dopamine receptor-interacting protein 1;
GN   Name=C14orf28; Synonyms=DRIP1;
//
ID   CN037_HUMAN             Reviewed;         774 AA.
AC   Q86TY3; A8K8Z8; Q6P5Q1; Q86TY1;
DE   RecName: Full=Uncharacterized protein C14orf37;
DE   Flags: Precursor;
GN   Name=C14orf37;
//
ID   CN048_HUMAN             Reviewed;         140 AA.
AC   Q8NCU1; Q8N7S1;
DE   RecName: Full=Uncharacterized protein encoded LINC00521;
GN   Name=LINC00521; Synonyms=C14orf48;
//
ID   CN070_HUMAN             Reviewed;         105 AA.
AC   Q86TU6; A2RUP4;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00523;
GN   Name=LINC00523; Synonyms=C14orf70;
//
ID   CN079_HUMAN             Reviewed;         325 AA.
AC   Q96F83; B2RPK9; Q9BTP4;
DE   RecName: Full=Uncharacterized protein C14orf79;
GN   Name=C14orf79;
//
ID   CN080_HUMAN             Reviewed;         495 AA.
AC   Q86SX3; B5MDG3; E9PAQ4; Q86TT3; Q86TT4; Q86TT5; Q96B41; Q9H7H4;
DE   RecName: Full=Uncharacterized protein C14orf80;
GN   Name=C14orf80;
//
ID   CN105_HUMAN             Reviewed;         296 AA.
AC   Q9NVL8; Q53G04;
DE   RecName: Full=Uncharacterized protein C14orf105;
GN   Name=C14orf105;
//
ID   CN093_HUMAN             Reviewed;         538 AA.
AC   Q9H972; B7WP03; D3DS38; D3DS39; Q86SE6; Q96CF7; Q9HA68;
DE   RecName: Full=Uncharacterized protein C14orf93;
DE   Flags: Precursor;
GN   Name=C14orf93;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CN132_HUMAN             Reviewed;         173 AA.
AC   Q9NPU4; B2R7K5;
DE   RecName: Full=Putative uncharacterized protein C14orf132;
GN   Name=C14orf132;
//
ID   CN119_HUMAN             Reviewed;         140 AA.
AC   Q9NWQ9; Q6IAA7;
DE   RecName: Full=Uncharacterized protein C14orf119;
GN   Name=C14orf119; ORFNames=My028;
//
ID   CN139_HUMAN             Reviewed;         190 AA.
AC   Q9H761; Q6IA18;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00341;
GN   Name=LINC00341; Synonyms=C14orf139;
//
ID   CN144_HUMAN             Reviewed;          54 AA.
AC   Q96I85;
DE   RecName: Full=Putative uncharacterized protein C14orf144;
DE   Flags: Precursor;
GN   Name=C14orf144;
//
ID   CN142_HUMAN             Reviewed;         100 AA.
AC   Q9BXV9; Q0D2N1; Q0P6C4; Q3B7W5;
DE   RecName: Full=Uncharacterized protein C14orf142;
GN   Name=C14orf142;
//
ID   CN159_HUMAN             Reviewed;         616 AA.
AC   Q7Z3D6; B3KUI7; Q86SW3; Q86SX8; Q86SX9; Q86T08; Q86TV5; Q96GW5;
AC   Q9H7G0; Q9H8Y9; Q9H9W6;
DE   RecName: Full=UPF0317 protein C14orf159, mitochondrial;
DE   Flags: Precursor;
GN   Name=C14orf159; ORFNames=UNQ2439/PRO5000;
//
ID   CN164_HUMAN             Reviewed;         300 AA.
AC   A8MTL3;
DE   RecName: Full=RING finger protein C14orf164;
GN   Name=C14orf164;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CN165_HUMAN             Reviewed;         117 AA.
AC   Q86U02;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00596;
GN   Name=LINC00596; Synonyms=C14orf165;
//
ID   CN166_HUMAN             Reviewed;         244 AA.
AC   Q9Y224;
DE   RecName: Full=UPF0568 protein C14orf166;
DE   AltName: Full=CLE7 homolog;
DE            Short=CLE;
GN   Name=C14orf166; ORFNames=CGI-99;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CN178_HUMAN             Reviewed;         122 AA.
AC   Q8N769; Q2HIX2; Q3KNR7;
DE   RecName: Full=Uncharacterized protein C14orf178;
GN   Name=C14orf178;
//
ID   CN182_HUMAN             Reviewed;         154 AA.
AC   A1A4T8; A8MYX4;
DE   RecName: Full=Uncharacterized protein C14orf182;
GN   Name=C14orf182;
//
ID   CN183_HUMAN             Reviewed;         324 AA.
AC   Q8WXQ3;
DE   RecName: Full=Putative uncharacterized protein C14orf183;
GN   Name=C14orf183;
//
ID   CN177_HUMAN             Reviewed;         125 AA.
AC   Q52M58; Q8N7D2;
DE   RecName: Full=Putative uncharacterized protein C14orf177;
GN   Name=C14orf177;
//
ID   CN37_HUMAN              Reviewed;         421 AA.
AC   P09543;
DE   RecName: Full=2',3'-cyclic-nucleotide 3'-phosphodiesterase;
DE            Short=CNP;
DE            Short=CNPase;
DE            EC=3.1.4.37;
DE   Flags: Precursor;
GN   Name=CNP;
DR   GO; GO:0004113; F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0030551; F:cyclic nucleotide binding; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0009214; P:cyclic nucleotide catabolic process; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   CNAS1_HUMAN             Reviewed;         148 AA.
AC   Q8NCQ2;
DE   RecName: Full=Uncharacterized protein CSNK1G2-AS1;
DE   AltName: Full=CSNK1G2 antisense RNA 1;
DE   AltName: Full=CSNK1G2 antisense gene protein 1;
GN   Name=CSNK1G2-AS1; Synonyms=C19orf34;
//
ID   CNBD1_HUMAN             Reviewed;         436 AA.
AC   Q8NA66;
DE   RecName: Full=Cyclic nucleotide-binding domain-containing protein 1;
GN   Name=CNBD1;
//
ID   CNBD2_HUMAN             Reviewed;         576 AA.
AC   Q96M20; Q14C79; Q5JWY7; Q5T3S1; Q9BR36; Q9BWY5;
DE   RecName: Full=Cyclic nucleotide-binding domain-containing protein 2;
GN   Name=CNBD2; Synonyms=C20orf152;
//
ID   CNBP1_HUMAN             Reviewed;          81 AA.
AC   Q9NSA3; Q5T4V2;
DE   RecName: Full=Beta-catenin-interacting protein 1;
DE   AltName: Full=Inhibitor of beta-catenin and Tcf-4;
GN   Name=CTNNBIP1; Synonyms=ICAT;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0072201; P:negative regulation of mesenchymal cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060633; P:negative regulation of transcription initiation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0045657; P:positive regulation of monocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0002528; P:regulation of vascular permeability involved in acute inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CNBP_HUMAN              Reviewed;         177 AA.
AC   P62633; A8K7V4; B2RAV9; D3DNB9; D3DNC0; D3DNC1; E9PDR7; P20694;
AC   Q4JGY0; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3;
DE   RecName: Full=Cellular nucleic acid-binding protein;
DE            Short=CNBP;
DE   AltName: Full=Zinc finger protein 9;
GN   Name=CNBP; Synonyms=RNF163, ZNF9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNCG_HUMAN              Reviewed;          83 AA.
AC   Q13956; Q52LY7;
DE   RecName: Full=Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma;
DE            Short=GMP-PDE gamma;
DE            EC=3.1.4.35;
GN   Name=PDE6H;
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030553; F:cGMP binding; IEA:InterPro.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CND1_HUMAN              Reviewed;        1401 AA.
AC   Q15021; D3DUR4; Q8N6U3;
DE   RecName: Full=Condensin complex subunit 1;
DE   AltName: Full=Chromosome condensation-related SMC-associated protein 1;
DE   AltName: Full=Chromosome-associated protein D2;
DE            Short=hCAP-D2;
DE   AltName: Full=Non-SMC condensin I complex subunit D2;
DE   AltName: Full=XCAP-D2 homolog;
GN   Name=NCAPD2; Synonyms=CAPD2, CNAP1, KIAA0159;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
//
ID   CND2_HUMAN              Reviewed;         741 AA.
AC   Q15003; Q8TB87;
DE   RecName: Full=Condensin complex subunit 2;
DE   AltName: Full=Barren homolog protein 1;
DE   AltName: Full=Chromosome-associated protein H;
DE            Short=hCAP-H;
DE   AltName: Full=Non-SMC condensin I complex subunit H;
DE   AltName: Full=XCAP-H homolog;
GN   Name=NCAPH; Synonyms=BRRN, BRRN1, CAPH, KIAA0074;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
//
ID   CND3_HUMAN              Reviewed;        1015 AA.
AC   Q9BPX3; Q3MJE0; Q96SV9; Q9BUR3; Q9BVY1; Q9H914; Q9H9Z6; Q9HBI9;
DE   RecName: Full=Condensin complex subunit 3;
DE   AltName: Full=Chromosome-associated protein G;
DE   AltName: Full=Condensin subunit CAP-G;
DE            Short=hCAP-G;
DE   AltName: Full=Melanoma antigen NY-MEL-3;
DE   AltName: Full=Non-SMC condensin I complex subunit G;
DE   AltName: Full=XCAP-G homolog;
GN   Name=NCAPG; Synonyms=CAPG, NYMEL3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
//
ID   CNDD3_HUMAN             Reviewed;        1498 AA.
AC   P42695; A6NFS2; Q4KMQ9;
DE   RecName: Full=Condensin-2 complex subunit D3;
DE   AltName: Full=Non-SMC condensin II complex subunit D3;
DE            Short=hCAP-D3;
GN   Name=NCAPD3; Synonyms=CAPD3, KIAA0056;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
//
ID   CNDG2_HUMAN             Reviewed;        1143 AA.
AC   Q86XI2; A4D228; Q7Z3J9; Q8WUG8; Q9BRX6; Q9H8S2; Q9H9K6;
DE   RecName: Full=Condensin-2 complex subunit G2;
DE   AltName: Full=Chromosome-associated protein G2;
DE            Short=CAP-G2;
DE            Short=hCAP-G2;
DE   AltName: Full=Leucine zipper protein 5;
DE   AltName: Full=Non-SMC condensin II complex subunit G2;
GN   Name=NCAPG2; Synonyms=LUZP5;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CNDH2_HUMAN             Reviewed;         605 AA.
AC   Q6IBW4; B7WPH1; O43788; Q13391; Q96C14; Q96GJ0; Q9BQ71; Q9BUT3;
AC   Q9BVD1;
DE   RecName: Full=Condensin-2 complex subunit H2;
DE   AltName: Full=Chromosome-associated protein H2;
DE            Short=hCAP-H2;
DE   AltName: Full=Kleisin-beta;
DE   AltName: Full=Non-SMC condensin II complex subunit H2;
GN   Name=NCAPH2; Synonyms=CAPH2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CNDP1_HUMAN             Reviewed;         507 AA.
AC   Q96KN2; Q14D40; Q17S05; Q2TBG0; Q6UWK2; Q9BT98;
DE   RecName: Full=Beta-Ala-His dipeptidase;
DE            EC=3.4.13.20;
DE   AltName: Full=CNDP dipeptidase 1;
DE   AltName: Full=Carnosine dipeptidase 1;
DE   AltName: Full=Glutamate carboxypeptidase-like protein 2;
DE   AltName: Full=Serum carnosinase;
DE   Flags: Precursor;
GN   Name=CNDP1; Synonyms=CN1, CPGL2; ORFNames=UNQ1915/PRO4380;
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0034701; F:tripeptidase activity; IEA:InterPro.
//
ID   CNDP2_HUMAN             Reviewed;         475 AA.
AC   Q96KP4; B3KUG4; Q8WY59; Q9BQ94; Q9NVB4;
DE   RecName: Full=Cytosolic non-specific dipeptidase;
DE            EC=3.4.13.18;
DE   AltName: Full=CNDP dipeptidase 2;
DE   AltName: Full=Glutamate carboxypeptidase-like protein 1;
DE   AltName: Full=Peptidase A;
GN   Name=CNDP2; Synonyms=CN2, CPGL, PEPA;
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:Reactome.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0034701; F:tripeptidase activity; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006750; P:glutathione biosynthetic process; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CNEP1_HUMAN             Reviewed;         244 AA.
AC   O95476; D3DTN7; Q96GQ9;
DE   RecName: Full=CTD nuclear envelope phosphatase 1;
DE            EC=3.1.3.16;
DE   AltName: Full=Serine/threonine-protein phosphatase dullard;
GN   Name=CTDNEP1; Synonyms=DULLARD;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; IDA:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; IGI:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
//
ID   CNFN_HUMAN              Reviewed;         112 AA.
AC   Q9BYD5; B2R569;
DE   RecName: Full=Cornifelin;
GN   Name=CNFN;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   CNG1O_HUMAN             Reviewed;          81 AA.
AC   Q8IZM0;
DE   RecName: Full=Putative CNGA1-overlapping antisense gene protein;
DE   AltName: Full=Anti-CNG1;
//
ID   CNGA1_HUMAN             Reviewed;         690 AA.
AC   P29973; A8K7K6; J3KPZ2; Q16279; Q16485; Q4W5E3;
DE   RecName: Full=cGMP-gated cation channel alpha-1;
DE   AltName: Full=Cyclic nucleotide-gated cation channel 1;
DE   AltName: Full=Cyclic nucleotide-gated channel alpha-1;
DE            Short=CNG channel alpha-1;
DE            Short=CNG-1;
DE            Short=CNG1;
DE   AltName: Full=Cyclic nucleotide-gated channel, photoreceptor;
DE   AltName: Full=Rod photoreceptor cGMP-gated channel subunit alpha;
GN   Name=CNGA1; Synonyms=CNCG, CNCG1;
DR   GuidetoPHARMACOLOGY; 394; -.
DR   GO; GO:0030553; F:cGMP binding; IBA:RefGenome.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CNGA2_HUMAN             Reviewed;         664 AA.
AC   Q16280; A0AVD0;
DE   RecName: Full=Cyclic nucleotide-gated olfactory channel;
DE   AltName: Full=Cyclic nucleotide-gated cation channel 2;
DE   AltName: Full=Cyclic nucleotide-gated channel alpha-2;
DE            Short=CNG channel alpha-2;
DE            Short=CNG-2;
DE            Short=CNG2;
GN   Name=CNGA2; Synonyms=CNCA, CNCA1, CNCG2;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030553; F:cGMP binding; IBA:RefGenome.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0007603; P:phototransduction, visible light; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
//
ID   CNGA3_HUMAN             Reviewed;         694 AA.
AC   Q16281; Q4VAP7; Q53RD2; Q9UP64;
DE   RecName: Full=Cyclic nucleotide-gated cation channel alpha-3;
DE   AltName: Full=Cone photoreceptor cGMP-gated channel subunit alpha;
DE   AltName: Full=Cyclic nucleotide-gated channel alpha-3;
DE            Short=CNG channel alpha-3;
DE            Short=CNG-3;
DE            Short=CNG3;
GN   Name=CNGA3; Synonyms=CNCG3;
DR   GuidetoPHARMACOLOGY; 396; -.
DR   GO; GO:0030553; F:cGMP binding; IMP:UniProt.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IMP:UniProt.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0006812; P:cation transport; IMP:UniProt.
DR   GO; GO:0007603; P:phototransduction, visible light; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0046549; P:retinal cone cell development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CNGA4_HUMAN             Reviewed;         575 AA.
AC   Q8IV77;
DE   RecName: Full=Cyclic nucleotide-gated cation channel alpha-4;
DE   AltName: Full=Cyclic nucleotide-gated channel alpha-4;
DE            Short=CNG channel alpha-4;
DE            Short=CNG-4;
DE            Short=CNG4;
GN   Name=CNGA4;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030553; F:cGMP binding; IBA:RefGenome.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0007603; P:phototransduction, visible light; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
//
ID   CNGB1_HUMAN             Reviewed;        1251 AA.
AC   Q14028; H3BN09; O43636; Q13059; Q14029; Q9UMG2;
DE   RecName: Full=Cyclic nucleotide-gated cation channel beta-1;
DE   AltName: Full=Cyclic nucleotide-gated cation channel 4;
DE            Short=CNG channel 4;
DE            Short=CNG-4;
DE            Short=CNG4;
DE   AltName: Full=Cyclic nucleotide-gated cation channel gamma;
DE   AltName: Full=Cyclic nucleotide-gated cation channel modulatory subunit;
DE   AltName: Full=Cyclic nucleotide-gated channel beta-1;
DE            Short=CNG channel beta-1;
DE   AltName: Full=Glutamic acid-rich protein;
DE            Short=GARP;
GN   Name=CNGB1; Synonyms=CNCG2, CNCG3L, CNCG4, RCNC2;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030553; F:cGMP binding; IDA:UniProt.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IEA:Ensembl.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IDA:UniProt.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0006812; P:cation transport; IDA:UniProt.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProt.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IMP:UniProt.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CNGB3_HUMAN             Reviewed;         809 AA.
AC   Q9NQW8; C9JA51; Q9NRE9;
DE   RecName: Full=Cyclic nucleotide-gated cation channel beta-3;
DE   AltName: Full=Cone photoreceptor cGMP-gated channel subunit beta;
DE   AltName: Full=Cyclic nucleotide-gated cation channel modulatory subunit;
DE   AltName: Full=Cyclic nucleotide-gated channel beta-3;
DE            Short=CNG channel beta-3;
GN   Name=CNGB3;
DR   GO; GO:0030553; F:cGMP binding; IDA:UniProt.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IBA:RefGenome.
DR   GO; GO:0005223; F:intracellular cGMP activated cation channel activity; IDA:UniProt.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0006812; P:cation transport; IDA:UniProt.
DR   GO; GO:0007603; P:phototransduction, visible light; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CNIH1_HUMAN             Reviewed;         144 AA.
AC   O95406; Q3SYM7;
DE   RecName: Full=Protein cornichon homolog 1;
DE            Short=CNIH-1;
DE   AltName: Full=Cornichon family AMPA receptor auxiliary protein 1;
DE   AltName: Full=Protein cornichon homolog;
DE   AltName: Full=T-cell growth-associated molecule 77;
DE            Short=TGAM77;
GN   Name=CNIH1; Synonyms=CNIH, CNIL; ORFNames=UNQ155/PRO181;
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   CNIH2_HUMAN             Reviewed;         160 AA.
AC   Q6PI25;
DE   RecName: Full=Protein cornichon homolog 2;
DE            Short=CNIH-2;
DE   AltName: Full=Cornichon family AMPA receptor auxiliary protein 2;
DE   AltName: Full=Cornichon-like protein;
GN   Name=CNIH2; Synonyms=CNIL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0051668; P:localization within membrane; IEA:Ensembl.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
//
ID   CNIH3_HUMAN             Reviewed;         160 AA.
AC   Q8TBE1;
DE   RecName: Full=Protein cornichon homolog 3;
DE            Short=CNIH-3;
DE   AltName: Full=Cornichon family AMPA receptor auxiliary protein 3;
GN   Name=CNIH3;
DR   GO; GO:0016247; F:channel regulator activity; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
//
ID   CNIH4_HUMAN             Reviewed;         139 AA.
AC   Q9P003; A8K1Q8; B2R553; Q9H0X8;
DE   RecName: Full=Protein cornichon homolog 4;
DE            Short=CNIH-4;
DE   AltName: Full=Cornichon family AMPA receptor auxiliary protein 4;
GN   Name=CNIH4; ORFNames=HSPC163;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   CNKR1_HUMAN             Reviewed;         720 AA.
AC   Q969H4; B1AMW9; O95381;
DE   RecName: Full=Connector enhancer of kinase suppressor of ras 1;
DE            Short=Connector enhancer of KSR 1;
DE   AltName: Full=CNK homolog protein 1;
DE            Short=CNK1;
DE            Short=hCNK1;
DE   AltName: Full=Connector enhancer of KSR-like;
GN   Name=CNKSR1; Synonyms=CNK1;
DR   GO; GO:0030674; F:protein binding, bridging; IDA:MGI.
DR   GO; GO:0007265; P:Ras protein signal transduction; IPI:MGI.
DR   GO; GO:0007266; P:Rho protein signal transduction; IPI:MGI.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   CNKR2_HUMAN             Reviewed;        1034 AA.
AC   Q8WXI2; B4DGR4; B7ZLJ1; B9EG83; E7ESA4; O94976; Q5JPK4; Q5JPN0;
AC   Q8WXI1;
DE   RecName: Full=Connector enhancer of kinase suppressor of ras 2;
DE            Short=Connector enhancer of KSR 2;
DE   AltName: Full=CNK homolog protein 2;
DE            Short=CNK2;
GN   Name=CNKSR2; Synonyms=CNK2, KIAA0902, KSR2;
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   CNKR3_HUMAN             Reviewed;         555 AA.
AC   Q6P9H4; Q5SGD5; Q96N65;
DE   RecName: Full=Connector enhancer of kinase suppressor of ras 3;
DE            Short=Connector enhancer of KSR 3;
DE   AltName: Full=CNK homolog protein 3;
DE            Short=CNK3;
DE   AltName: Full=CNKSR family member 3;
DE   AltName: Full=Maguin-like protein;
GN   Name=CNKSR3; Synonyms=MAGI1;
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; ISS:UniProtKB.
//
ID   CNN1_HUMAN              Reviewed;         297 AA.
AC   P51911; B2R868; O00638; Q15416; Q8IY93; Q99438;
DE   RecName: Full=Calponin-1;
DE   AltName: Full=Basic calponin;
DE   AltName: Full=Calponin H1, smooth muscle;
GN   Name=CNN1;
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:InterPro.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.
//
ID   CNN2_HUMAN              Reviewed;         309 AA.
AC   Q99439; A5D8U8; A6NFI4; D6W5X9; Q92578;
DE   RecName: Full=Calponin-2;
DE   AltName: Full=Calponin H2, smooth muscle;
DE   AltName: Full=Neutral calponin;
GN   Name=CNN2;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:InterPro.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IDA:MGI.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032970; P:regulation of actin filament-based process; IDA:MGI.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   CNN3_HUMAN              Reviewed;         329 AA.
AC   Q15417; Q6FHA7;
DE   RecName: Full=Calponin-3;
DE   AltName: Full=Calponin, acidic isoform;
GN   Name=CNN3;
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:InterPro.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
//
ID   CNNM1_HUMAN             Reviewed;         951 AA.
AC   Q9NRU3; Q4QQG7; Q4QQH8; Q4QQP9; Q9NT45;
DE   RecName: Full=Metal transporter CNNM1;
DE   AltName: Full=Ancient conserved domain-containing protein 1;
DE   AltName: Full=Cyclin-M1;
GN   Name=CNNM1; Synonyms=ACDP1;
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   CNNM2_HUMAN             Reviewed;         875 AA.
AC   Q9H8M5; Q5T569; Q5T570; Q8WU59; Q9H952; Q9NRK5; Q9NXT4;
DE   RecName: Full=Metal transporter CNNM2;
DE   AltName: Full=Ancient conserved domain-containing protein 2;
DE   AltName: Full=Cyclin-M2;
GN   Name=CNNM2; Synonyms=ACDP2;
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0010960; P:magnesium ion homeostasis; IMP:MGI.
DR   GO; GO:0015693; P:magnesium ion transport; IEA:Ensembl.
//
ID   CNNM3_HUMAN             Reviewed;         707 AA.
AC   Q8NE01; B3KX67; Q8TBV4; Q96IW4; Q9NRK4; Q9NXW6;
DE   RecName: Full=Metal transporter CNNM3;
DE   AltName: Full=Ancient conserved domain-containing protein 3;
DE   AltName: Full=Cyclin-M3;
GN   Name=CNNM3; Synonyms=ACDP3;
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   CNNM4_HUMAN             Reviewed;         775 AA.
AC   Q6P4Q7; B7Z1U0; C7SQM3; C7SQM4; C7SQM5; Q53RE5; Q9H9G3; Q9HCI0;
AC   Q9NRN1;
DE   RecName: Full=Metal transporter CNNM4;
DE   AltName: Full=Ancient conserved domain-containing protein 4;
DE   AltName: Full=Cyclin-M4;
GN   Name=CNNM4; Synonyms=ACDP4, KIAA1592;
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   CNO10_HUMAN             Reviewed;         744 AA.
AC   Q9H9A5; B7Z7L1; F8WAF2; Q9BU30; Q9H5J7; Q9H8X1; Q9H9W0; Q9HAH3;
AC   Q9UFJ2;
DE   RecName: Full=CCR4-NOT transcription complex subunit 10;
GN   Name=CNOT10;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNO11_HUMAN             Reviewed;         510 AA.
AC   Q9UKZ1; Q6P2M9; Q8N681;
DE   RecName: Full=CCR4-NOT transcription complex subunit 11;
GN   Name=CNOT11; Synonyms=C2orf29; ORFNames=C40;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNO6L_HUMAN             Reviewed;         555 AA.
AC   Q96LI5; Q9UF92;
DE   RecName: Full=CCR4-NOT transcription complex subunit 6-like;
DE            EC=3.1.13.4;
DE   AltName: Full=Carbon catabolite repressor protein 4 homolog B;
GN   Name=CNOT6L; Synonyms=CCR4B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0061157; P:mRNA destabilization; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010606; P:positive regulation of cytoplasmic mRNA processing body assembly; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; TAS:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNOT1_HUMAN             Reviewed;        2376 AA.
AC   A5YKK6; Q68DX7; Q7Z3K2; Q8IWB8; Q8TB53; Q9BVZ6; Q9UFR8; Q9UI27;
AC   Q9Y2L0;
DE   RecName: Full=CCR4-NOT transcription complex subunit 1;
DE   AltName: Full=CCR4-associated factor 1;
DE   AltName: Full=Negative regulator of transcription subunit 1 homolog;
DE            Short=NOT1H;
DE            Short=hNOT1;
GN   Name=CNOT1; Synonyms=CDC39, KIAA1007, NOT1; ORFNames=AD-005;
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0010606; P:positive regulation of cytoplasmic mRNA processing body assembly; IDA:UniProtKB.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IMP:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:UniProtKB.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNOT2_HUMAN             Reviewed;         540 AA.
AC   Q9NZN8; Q9H3E0; Q9NSX5; Q9NWR6; Q9P028;
DE   RecName: Full=CCR4-NOT transcription complex subunit 2;
DE   AltName: Full=CCR4-associated factor 2;
GN   Name=CNOT2; Synonyms=CDC36, NOT2; ORFNames=HSPC131, MSTP046;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; TAS:UniProtKB.
DR   GO; GO:0001226; F:RNA polymerase II transcription corepressor binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0010606; P:positive regulation of cytoplasmic mRNA processing body assembly; IMP:UniProtKB.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IMP:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IMP:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   CNOT3_HUMAN             Reviewed;         753 AA.
AC   O75175; Q9NZN7; Q9UF76;
DE   RecName: Full=CCR4-NOT transcription complex subunit 3;
DE   AltName: Full=CCR4-associated factor 3;
DE   AltName: Full=Leukocyte receptor cluster member 2;
GN   Name=CNOT3; Synonyms=KIAA0691, LENG2, NOT3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   CNOT4_HUMAN             Reviewed;         575 AA.
AC   O95628; B7Z6I4; E7ET38; F8VQP3; O95339; O95627; Q8IYM7; Q8NCL0;
AC   Q9NPQ1; Q9NZN6;
DE   RecName: Full=CCR4-NOT transcription complex subunit 4;
DE            EC=6.3.2.-;
DE   AltName: Full=CCR4-associated factor 4;
DE   AltName: Full=E3 ubiquitin-protein ligase CNOT4;
DE   AltName: Full=Potential transcriptional repressor NOT4Hp;
GN   Name=CNOT4; Synonyms=NOT4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   CNOT6_HUMAN             Reviewed;         557 AA.
AC   Q9ULM6; A7MD46; D3DWR0;
DE   RecName: Full=CCR4-NOT transcription complex subunit 6;
DE            EC=3.1.13.4;
DE   AltName: Full=CCR4 carbon catabolite repression 4-like;
DE   AltName: Full=Carbon catabolite repressor protein 4 homolog;
DE   AltName: Full=Cytoplasmic deadenylase;
GN   Name=CNOT6; Synonyms=CCR4, CCR4a, KIAA1194;
DR   GO; GO:0004532; F:exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035195; P:gene silencing by miRNA; TAS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0070966; P:nuclear-transcribed mRNA catabolic process, no-go decay; IMP:UniProtKB.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010606; P:positive regulation of cytoplasmic mRNA processing body assembly; IMP:UniProtKB.
DR   GO; GO:2000327; P:positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNOT7_HUMAN             Reviewed;         285 AA.
AC   Q9UIV1; A8MZM5; B3KMP1; B3KN35; D3DSP6; G3V108; Q7Z530;
DE   RecName: Full=CCR4-NOT transcription complex subunit 7;
DE            EC=3.1.13.4;
DE   AltName: Full=BTG1-binding factor 1;
DE   AltName: Full=CCR4-associated factor 1;
DE            Short=CAF-1;
DE   AltName: Full=Caf1a;
GN   Name=CNOT7; Synonyms=CAF1;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0004532; F:exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IEA:Ensembl.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:Ensembl.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035195; P:gene silencing by miRNA; TAS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IMP:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNOT8_HUMAN             Reviewed;         292 AA.
AC   Q9UFF9; B2RAR8; D3DQI8; O95709; Q7Z521; Q9H6Y1;
DE   RecName: Full=CCR4-NOT transcription complex subunit 8;
DE            EC=3.1.13.4;
DE   AltName: Full=CAF1-like protein;
DE            Short=CALIFp;
DE   AltName: Full=CAF2;
DE   AltName: Full=CCR4-associated factor 8;
DE   AltName: Full=Caf1b;
GN   Name=CNOT8; Synonyms=CALIF, POP2;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035195; P:gene silencing by miRNA; TAS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CNPD1_HUMAN             Reviewed;         410 AA.
AC   Q9BV87; B2RC77; O75548; Q9H4N0; Q9UQN0;
DE   RecName: Full=Protein CNPPD1;
DE   AltName: Full=Cyclin Pas1/PHO80 domain-containing protein 1;
GN   Name=CNPPD1; Synonyms=C2orf24; ORFNames=CDABP0125, CGI-57;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
//
ID   CNPY1_HUMAN             Reviewed;          92 AA.
AC   Q3B7I2; A6NGX3;
DE   RecName: Full=Protein canopy homolog 1;
GN   Name=CNPY1;
//
ID   CNPY2_HUMAN             Reviewed;         182 AA.
AC   Q9Y2B0; B2R7B9; Q9UHE9;
DE   RecName: Full=Protein canopy homolog 2;
DE   AltName: Full=MIR-interacting saposin-like protein;
DE   AltName: Full=Putative secreted protein Zsig9;
DE   AltName: Full=Transmembrane protein 4;
DE   Flags: Precursor;
GN   Name=CNPY2; Synonyms=MSAP, TMEM4, ZSIG9; ORFNames=UNQ1943/PRO4426;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0045716; P:positive regulation of low-density lipoprotein particle receptor biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0010988; P:regulation of low-density lipoprotein particle clearance; ISS:BHF-UCL.
//
ID   CNPY3_HUMAN             Reviewed;         278 AA.
AC   Q9BT09; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9P0F2;
DE   RecName: Full=Protein canopy homolog 3;
DE   AltName: Full=CTG repeat protein 4a;
DE   AltName: Full=Expanded repeat-domain protein CAG/CTG 5;
DE   AltName: Full=Protein associated with TLR4;
DE   AltName: Full=Trinucleotide repeat-containing gene 5 protein;
DE   Flags: Precursor;
GN   Name=CNPY3; Synonyms=CTG4A, ERDA5, PRAT4A, TNRC5;
GN   ORFNames=HSPC084, UNQ1934/PRO4409;
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   CNPY4_HUMAN             Reviewed;         248 AA.
AC   Q8N129; Q8WUN9;
DE   RecName: Full=Protein canopy homolog 4;
DE   Flags: Precursor;
GN   Name=CNPY4; ORFNames=PSEC0237, UNQ1909/PRO4354;
//
ID   CNR1_HUMAN              Reviewed;         472 AA.
AC   P21554; B2R9T4; E1P512; Q13949; Q495Z0; Q4PLI4; Q4VBM6; Q5JVL5;
AC   Q5UB37; Q9UNN0;
DE   RecName: Full=Cannabinoid receptor 1;
DE            Short=CB-R;
DE            Short=CB1;
DE   AltName: Full=CANN6;
GN   Name=CNR1; Synonyms=CNR;
DR   GuidetoPHARMACOLOGY; 56; -.
DR   GO; GO:0004949; F:cannabinoid receptor activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0045759; P:negative regulation of action potential; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0033602; P:negative regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0031999; P:negative regulation of fatty acid beta-oxidation; IEA:Ensembl.
DR   GO; GO:0033004; P:negative regulation of mast cell activation; IEA:Ensembl.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0002866; P:positive regulation of acute inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0031622; P:positive regulation of fever generation; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0060259; P:regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0060405; P:regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CNR2_HUMAN              Reviewed;         360 AA.
AC   P34972; C6ES44; Q4VBK8; Q5JRH7; Q6B0G7; Q6NSY0;
DE   RecName: Full=Cannabinoid receptor 2;
DE            Short=CB-2;
DE            Short=CB2;
DE            Short=hCB2;
DE   AltName: Full=CX5;
GN   Name=CNR2; Synonyms=CB2A, CB2B;
DR   GuidetoPHARMACOLOGY; 57; -.
DR   GO; GO:0004949; F:cannabinoid receptor activity; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045759; P:negative regulation of action potential; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0033004; P:negative regulation of mast cell activation; IEA:Ensembl.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
//
ID   CNRG_HUMAN              Reviewed;          87 AA.
AC   P18545; Q3KP63; Q7Z3U8;
DE   RecName: Full=Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma;
DE            Short=GMP-PDE gamma;
DE            EC=3.1.4.35;
GN   Name=PDE6G; Synonyms=PDEG;
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030553; F:cGMP binding; IEA:InterPro.
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CNRP1_HUMAN             Reviewed;         164 AA.
AC   Q96F85; B2R4D0; Q49AN4; Q9UFZ0;
DE   RecName: Full=CB1 cannabinoid receptor-interacting protein 1;
DE            Short=CRIP-1;
GN   Name=CNRIP1; Synonyms=C2orf32;
//
ID   CNST_HUMAN              Reviewed;         725 AA.
AC   Q6PJW8; Q5VSY9; Q5VTM7; Q8IYA9; Q8N3L5; Q8NB09; Q8TEI2; Q96MR5;
DE   RecName: Full=Consortin;
GN   Name=CNST; Synonyms=C1orf71;
DR   GO; GO:0071253; F:connexin binding; ISS:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042998; P:positive regulation of Golgi to plasma membrane protein transport; IMP:UniProtKB.
//
ID   CNT3B_HUMAN             Reviewed;        1288 AA.
AC   Q96NU0; B1B0V7; B1B0V8; B1B0V9; B1B0W0; B1B0X8; B1B162; Q4VXF0;
AC   Q9H7W3;
DE   RecName: Full=Contactin-associated protein-like 3B;
DE   AltName: Full=Cell recognition molecule Caspr3b;
DE   Flags: Precursor;
GN   Name=CNTNAP3B; Synonyms=CASPR3B;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CNTD1_HUMAN             Reviewed;         330 AA.
AC   Q8N815; Q658Q6; Q8NEP1;
DE   RecName: Full=Cyclin N-terminal domain-containing protein 1;
GN   Name=CNTD1; Synonyms=CNTD;
//
ID   CNTD2_HUMAN             Reviewed;         307 AA.
AC   Q9H8S5; B4DX65;
DE   RecName: Full=Cyclin N-terminal domain-containing protein 2;
GN   Name=CNTD2;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
//
ID   CNTFR_HUMAN             Reviewed;         372 AA.
AC   P26992; Q5U050;
DE   RecName: Full=Ciliary neurotrophic factor receptor subunit alpha;
DE            Short=CNTF receptor subunit alpha;
DE            Short=CNTFR-alpha;
DE   Flags: Precursor;
GN   Name=CNTFR;
DR   GO; GO:0004897; F:ciliary neurotrophic factor receptor activity; TAS:ProtInc.
DR   GO; GO:0019955; F:cytokine binding; IPI:HGNC.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0003360; P:brainstem development; IEA:Ensembl.
DR   GO; GO:0070120; P:ciliary neurotrophic factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007548; P:sex differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0060538; P:skeletal muscle organ development; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
//
ID   CNTF_HUMAN              Reviewed;         200 AA.
AC   P26441; B2RAB2;
DE   RecName: Full=Ciliary neurotrophic factor;
DE            Short=CNTF;
GN   Name=CNTF;
DR   GO; GO:0005127; F:ciliary neurotrophic factor receptor binding; TAS:ProtInc.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005138; F:interleukin-6 receptor binding; IPI:BHF-UCL.
DR   GO; GO:0070120; P:ciliary neurotrophic factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0046533; P:negative regulation of photoreceptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0046668; P:regulation of retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CNTLN_HUMAN             Reviewed;        1405 AA.
AC   Q9NXG0; A5Z2X6; Q5VYJ0; Q8N1G9; Q9HAJ5;
DE   RecName: Full=Centlein;
DE   AltName: Full=Centrosomal protein;
GN   Name=CNTLN; Synonyms=C9orf101, C9orf39;
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
//
ID   CNTN1_HUMAN             Reviewed;        1018 AA.
AC   Q12860; A8K0H9; A8K0Y3; Q12861; Q14030; Q7M4P0; Q8N466;
DE   RecName: Full=Contactin-1;
DE   AltName: Full=Glycoprotein gp135;
DE   AltName: Full=Neural cell surface protein F3;
DE   Flags: Precursor;
GN   Name=CNTN1;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
//
ID   CNTN2_HUMAN             Reviewed;        1040 AA.
AC   Q02246; P78432; Q5T054;
DE   RecName: Full=Contactin-2;
DE   AltName: Full=Axonal glycoprotein TAG-1;
DE   AltName: Full=Axonin-1;
DE   AltName: Full=Transient axonal glycoprotein 1;
DE            Short=TAX-1;
DE   Flags: Precursor;
GN   Name=CNTN2; Synonyms=AXT, TAG1, TAX1;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; TAS:BHF-UCL.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0034613; P:cellular protein localization; ISS:BHF-UCL.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0021853; P:cerebral cortex GABAergic interneuron migration; IEA:Ensembl.
DR   GO; GO:0045163; P:clustering of voltage-gated potassium channels; ISS:BHF-UCL.
DR   GO; GO:0071206; P:establishment of protein localization to juxtaparanode region of axon; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0060168; P:positive regulation of adenosine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010954; P:positive regulation of protein processing; IEA:Ensembl.
DR   GO; GO:0097090; P:presynaptic membrane organization; IMP:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IEA:Ensembl.
DR   GO; GO:0048710; P:regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0031133; P:regulation of axon diameter; IEA:Ensembl.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
//
ID   CNTN3_HUMAN             Reviewed;        1028 AA.
AC   Q9P232; B9EK50; Q9H039;
DE   RecName: Full=Contactin-3;
DE   AltName: Full=Brain-derived immunoglobulin superfamily protein 1;
DE            Short=BIG-1;
DE   AltName: Full=Plasmacytoma-associated neuronal glycoprotein;
DE   Flags: Precursor;
GN   Name=CNTN3; Synonyms=KIAA1496, PANG;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
//
ID   CNTN4_HUMAN             Reviewed;        1026 AA.
AC   Q8IWV2; B2RAX3; Q8IX14; Q8TC35;
DE   RecName: Full=Contactin-4;
DE   AltName: Full=Brain-derived immunoglobulin superfamily protein 2;
DE            Short=BIG-2;
DE   Flags: Precursor;
GN   Name=CNTN4;
DR   GO; GO:0007411; P:axon guidance; TAS:UniProtKB.
DR   GO; GO:0007413; P:axonal fasciculation; TAS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; TAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; TAS:UniProtKB.
//
ID   CNTN5_HUMAN             Reviewed;        1100 AA.
AC   O94779; A1L4P0; B7ZM07; E9PKE8; O94780; Q49AF3;
DE   RecName: Full=Contactin-5;
DE   AltName: Full=Neural recognition molecule NB-2;
DE            Short=hNB-2;
DE   Flags: Precursor;
GN   Name=CNTN5;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   CNTN6_HUMAN             Reviewed;        1028 AA.
AC   Q9UQ52; Q2KHM2;
DE   RecName: Full=Contactin-6;
DE   AltName: Full=Neural recognition molecule NB-3;
DE            Short=hNB-3;
DE   Flags: Precursor;
GN   Name=CNTN6;
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
//
ID   CNTP1_HUMAN             Reviewed;        1384 AA.
AC   P78357;
DE   RecName: Full=Contactin-associated protein 1;
DE            Short=Caspr;
DE            Short=Caspr1;
DE   AltName: Full=Neurexin IV;
DE   AltName: Full=Neurexin-4;
DE   AltName: Full=p190;
DE   Flags: Precursor;
GN   Name=CNTNAP1; Synonyms=CASPR, NRXN4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0008088; P:axon cargo transport; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0019227; P:neuronal action potential propagation; ISS:BHF-UCL.
DR   GO; GO:0030913; P:paranodal junction assembly; ISS:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0002175; P:protein localization to paranode region of axon; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CNTP2_HUMAN             Reviewed;        1331 AA.
AC   Q9UHC6; D3DWG2; Q14DG2; Q52LV1; Q5H9Q7; Q9UQ12;
DE   RecName: Full=Contactin-associated protein-like 2;
DE   AltName: Full=Cell recognition molecule Caspr2;
DE   Flags: Precursor;
GN   Name=CNTNAP2; Synonyms=CASPR2, KIAA0868;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0007420; P:brain development; TAS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034613; P:cellular protein localization; ISS:BHF-UCL.
DR   GO; GO:0021987; P:cerebral cortex development; IEP:BHF-UCL.
DR   GO; GO:0045163; P:clustering of voltage-gated potassium channels; ISS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0021761; P:limbic system development; IEP:BHF-UCL.
DR   GO; GO:0031175; P:neuron projection development; ISS:BHF-UCL.
DR   GO; GO:0008038; P:neuron recognition; NAS:UniProtKB.
DR   GO; GO:0071205; P:protein localization to juxtaparanode region of axon; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0021756; P:striatum development; IEP:BHF-UCL.
DR   GO; GO:0071109; P:superior temporal gyrus development; IEP:BHF-UCL.
DR   GO; GO:0021794; P:thalamus development; IEP:BHF-UCL.
DR   GO; GO:0019226; P:transmission of nerve impulse; NAS:UniProtKB.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   CNTP3_HUMAN             Reviewed;        1288 AA.
AC   Q9BZ76; B1AMA0; Q9C0E9;
DE   RecName: Full=Contactin-associated protein-like 3;
DE   AltName: Full=Cell recognition molecule Caspr3;
DE   Flags: Precursor;
GN   Name=CNTNAP3; Synonyms=CASPR3, KIAA1714;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008037; P:cell recognition; NAS:UniProtKB.
//
ID   CNTP4_HUMAN             Reviewed;        1308 AA.
AC   Q9C0A0; E9PFZ6; Q86YZ7;
DE   RecName: Full=Contactin-associated protein-like 4;
DE   AltName: Full=Cell recognition molecule Caspr4;
DE   Flags: Precursor;
GN   Name=CNTNAP4; Synonyms=CASPR4, KIAA1763;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CNTP5_HUMAN             Reviewed;        1306 AA.
AC   Q8WYK1; Q4ZFW2; Q4ZG21; Q53R09; Q53RX1; Q53SG3; Q584P3; Q96MS7;
DE   RecName: Full=Contactin-associated protein-like 5;
DE   AltName: Full=Cell recognition molecule Caspr5;
DE   Flags: Precursor;
GN   Name=CNTNAP5; Synonyms=CASPR5;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   CNTRB_HUMAN             Reviewed;         903 AA.
AC   Q8N137; A6NHQ1; Q331K3; Q69YV7; Q8NCB8; Q8WXV3; Q96CQ7; Q9C060;
DE   RecName: Full=Centrobin;
DE   AltName: Full=Centrosomal BRCA2-interacting protein;
DE   AltName: Full=LYST-interacting protein 8;
GN   Name=CNTROB; Synonyms=LIP8; ORFNames=PP1221;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0007099; P:centriole replication; IMP:HGNC.
DR   GO; GO:0051299; P:centrosome separation; IMP:HGNC.
DR   GO; GO:0000910; P:cytokinesis; IMP:HGNC.
//
ID   CNTRL_HUMAN             Reviewed;        2325 AA.
AC   Q7Z7A1; A2A2Y1; B2RP67; Q3MN79; Q5FWF8; Q5JVD0; Q6MZR3; Q6PKC1;
AC   Q8TEP3; Q9Y489;
DE   RecName: Full=Centriolin;
DE   AltName: Full=Centrosomal protein 1;
DE   AltName: Full=Centrosomal protein of 110 kDa;
DE            Short=Cep110;
GN   Name=CNTRL; Synonyms=CEP1, CEP110;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CO005_HUMAN             Reviewed;          94 AA.
AC   Q9H2U6; Q3SY27; Q9UMC1;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00597;
GN   Name=LINC00597; Synonyms=C15orf5;
//
ID   CO026_HUMAN             Reviewed;         301 AA.
AC   Q6P656; Q8N906;
DE   RecName: Full=Uncharacterized protein C15orf26;
GN   Name=C15orf26;
//
ID   CO027_HUMAN             Reviewed;         531 AA.
AC   Q2M3C6; Q8N993; Q96LL5;
DE   RecName: Full=Transmembrane protein C15orf27;
GN   Name=C15orf27;
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
//
ID   CO032_HUMAN             Reviewed;         178 AA.
AC   Q32M92; C5HTZ8; Q96M45;
DE   RecName: Full=Uncharacterized protein C15orf32;
GN   Name=C15orf32;
//
ID   CO037_HUMAN             Reviewed;         130 AA.
AC   Q8NBB2;
DE   RecName: Full=Putative uncharacterized protein C15orf37;
GN   Name=C15orf37;
//
ID   CO039_HUMAN             Reviewed;        1047 AA.
AC   Q6ZRI6; B3KWI3; C9J888; Q71JB1; Q7L3S0; Q8N3F2; Q96FB6; Q9NTU5;
DE   RecName: Full=Uncharacterized protein C15orf39;
GN   Name=C15orf39; ORFNames=FP6578;
//
ID   CO041_HUMAN             Reviewed;         281 AA.
AC   Q9Y2V0; B2RD87;
DE   RecName: Full=Uncharacterized protein C15orf41;
DE   AltName: Full=Protein HH114;
GN   Name=C15orf41;
//
ID   CO040_HUMAN             Reviewed;         153 AA.
AC   Q8WUR7; A6NIC9; B2R5E7; F5GX92; F8WD31; G5EA00;
DE   RecName: Full=UPF0235 protein C15orf40;
GN   Name=C15orf40;
//
ID   CO043_HUMAN             Reviewed;         220 AA.
AC   Q8NHR7;
DE   RecName: Full=Uncharacterized protein C15orf43;
GN   Name=C15orf43;
//
ID   CO052_HUMAN             Reviewed;         534 AA.
AC   Q6ZUT6; B9EIQ8; Q68DG9; Q6ZTM3; Q6ZU22;
DE   RecName: Full=Uncharacterized protein C15orf52;
GN   Name=C15orf52;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CO053_HUMAN             Reviewed;         179 AA.
AC   Q8NAA6;
DE   RecName: Full=Uncharacterized protein C15orf53;
GN   Name=C15orf53;
//
ID   CO054_HUMAN             Reviewed;         183 AA.
AC   Q8N8G6; B7ZVZ9;
DE   RecName: Full=Putative uncharacterized protein C15orf54;
GN   Name=C15orf54;
//
ID   CO056_HUMAN             Reviewed;         161 AA.
AC   Q8N910;
DE   RecName: Full=Putative uncharacterized protein C15orf56;
GN   Name=C15orf56;
//
ID   CO057_HUMAN             Reviewed;         185 AA.
AC   Q9BV29; A8KAL4; Q86TC4; Q8N788; Q8NAR7;
DE   RecName: Full=Uncharacterized protein C15orf57;
DE   AltName: Full=Protein CCDC32;
GN   Name=C15orf57; Synonyms=CCDC32;
//
ID   CO059_HUMAN             Reviewed;         293 AA.
AC   Q2T9L4;
DE   RecName: Full=UPF0583 protein C15orf59;
GN   Name=C15orf59;
//
ID   CO061_HUMAN             Reviewed;         157 AA.
AC   A6NNL5; B4DFB2;
DE   RecName: Full=Uncharacterized protein C15orf61;
DE   Flags: Precursor;
GN   Name=C15orf61;
//
ID   CO062_HUMAN             Reviewed;         175 AA.
AC   A8K5M9; A6NK01;
DE   RecName: Full=Uncharacterized protein C15orf62, mitochondrial;
DE   Flags: Precursor;
GN   Name=C15orf62;
//
ID   CO065_HUMAN             Reviewed;         121 AA.
AC   H3BRN8;
DE   RecName: Full=Uncharacterized protein C15orf65;
GN   Name=C15orf65;
//
ID   CO1A1_HUMAN             Reviewed;        1464 AA.
AC   P02452; O76045; P78441; Q13896; Q13902; Q13903; Q14037; Q14992;
AC   Q15176; Q15201; Q16050; Q59F64; Q7KZ30; Q7KZ34; Q8IVI5; Q8N473;
AC   Q9UML6; Q9UMM7;
DE   RecName: Full=Collagen alpha-1(I) chain;
DE   AltName: Full=Alpha-1 type I collagen;
DE   Flags: Precursor;
GN   Name=COL1A1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001568; P:blood vessel development; IMP:UniProtKB.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0032964; P:collagen biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:UniProtKB.
DR   GO; GO:0048706; P:embryonic skeletal system development; IMP:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0001957; P:intramembranous ossification; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0043589; P:skin morphogenesis; IMP:UniProtKB.
DR   GO; GO:0034505; P:tooth mineralization; IMP:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CO1A2_HUMAN             Reviewed;        1366 AA.
AC   P08123; P02464; Q13897; Q13997; Q13998; Q14038; Q14057; Q15177;
AC   Q15947; Q16480; Q16511; Q7Z5S6; Q9UEB6; Q9UEF9; Q9UM83; Q9UMI1;
AC   Q9UML5; Q9UMM6; Q9UPH0;
DE   RecName: Full=Collagen alpha-2(I) chain;
DE   AltName: Full=Alpha-2 type I collagen;
DE   Flags: Precursor;
GN   Name=COL1A2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001568; P:blood vessel development; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0042476; P:odontogenesis; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0043589; P:skin morphogenesis; IMP:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
//
ID   CO2A1_HUMAN             Reviewed;        1487 AA.
AC   P02458; A6NGA0; Q12985; Q14009; Q14044; Q14045; Q14046; Q14047;
AC   Q14056; Q14058; Q16672; Q1JQ82; Q2V4X7; Q6LBY1; Q6LBY2; Q6LBY3;
AC   Q96IT5; Q99227; Q9UE38; Q9UE39; Q9UE40; Q9UE41; Q9UE42; Q9UE43;
DE   RecName: Full=Collagen alpha-1(II) chain;
DE   AltName: Full=Alpha-1 type II collagen;
DE   Contains:
DE     RecName: Full=Collagen alpha-1(II) chain;
DE   Contains:
DE     RecName: Full=Chondrocalcin;
DE   Flags: Precursor;
GN   Name=COL2A1;
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IC:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; NAS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; TAS:BHF-UCL.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:BHF-UCL.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR   GO; GO:0071599; P:otic vesicle development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; IMP:BHF-UCL.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CO2_HUMAN               Reviewed;         752 AA.
AC   P06681; B4DPF3; B4DV20; E9PFN7; O19694; Q13904;
DE   RecName: Full=Complement C2;
DE            EC=3.4.21.43;
DE   AltName: Full=C3/C5 convertase;
DE   Contains:
DE     RecName: Full=Complement C2b fragment;
DE   Contains:
DE     RecName: Full=Complement C2a fragment;
DE   Flags: Precursor;
GN   Name=C2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO3A1_HUMAN             Reviewed;        1466 AA.
AC   P02461; D3DPH4; P78429; Q15112; Q16403; Q53S91; Q541P8; Q6LDB3;
AC   Q6LDJ2; Q6LDJ3; Q7KZ56; Q8N6U4; Q9UC88; Q9UC89; Q9UC90; Q9UC91;
DE   RecName: Full=Collagen alpha-1(III) chain;
DE   Flags: Precursor;
GN   Name=COL3A1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IMP:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:UniProtKB.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0043206; P:extracellular fibril organization; IMP:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0050777; P:negative regulation of immune response; IMP:UniProtKB.
DR   GO; GO:2001223; P:negative regulation of neuron migration; ISS:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IDA:UniProtKB.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IMP:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IDA:UniProtKB.
//
ID   CO3_HUMAN               Reviewed;        1663 AA.
AC   P01024; A7E236;
DE   RecName: Full=Complement C3;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1;
DE   Contains:
DE     RecName: Full=Complement C3 beta chain;
DE   Contains:
DE     RecName: Full=Complement C3 alpha chain;
DE   Contains:
DE     RecName: Full=C3a anaphylatoxin;
DE   Contains:
DE     RecName: Full=Acylation stimulating protein;
DE              Short=ASP;
DE     AltName: Full=C3adesArg;
DE   Contains:
DE     RecName: Full=Complement C3b alpha' chain;
DE   Contains:
DE     RecName: Full=Complement C3c alpha' chain fragment 1;
DE   Contains:
DE     RecName: Full=Complement C3dg fragment;
DE   Contains:
DE     RecName: Full=Complement C3g fragment;
DE   Contains:
DE     RecName: Full=Complement C3d fragment;
DE   Contains:
DE     RecName: Full=Complement C3f fragment;
DE   Contains:
DE     RecName: Full=Complement C3c alpha' chain fragment 2;
DE   Flags: Precursor;
GN   Name=C3; Synonyms=CPAMD1;
DR   GO; GO:0031715; F:C5L2 anaphylatoxin chemotactic receptor binding; IDA:UniProtKB.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006957; P:complement activation, alternative pathway; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001970; P:positive regulation of activation of membrane attack complex; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010828; P:positive regulation of glucose transport; IDA:UniProtKB.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IDA:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001798; P:positive regulation of type IIa hypersensitivity; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0010866; P:regulation of triglyceride biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CO4A1_HUMAN             Reviewed;        1669 AA.
AC   P02462; A7E2W4; B1AM70; Q1P9S9; Q5VWF6; Q86X41; Q8NF88; Q9NYC5;
DE   RecName: Full=Collagen alpha-1(IV) chain;
DE   Contains:
DE     RecName: Full=Arresten;
DE   Flags: Precursor;
GN   Name=COL4A1;
DR   GO; GO:0030023; F:extracellular matrix constituent conferring elasticity; IC:BHF-UCL.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IMP:BHF-UCL.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0071711; P:basement membrane organization; IMP:BHF-UCL.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0007420; P:brain development; IMP:BHF-UCL.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IMP:BHF-UCL.
DR   GO; GO:0061333; P:renal tubule morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0061304; P:retinal blood vessel morphogenesis; IMP:BHF-UCL.
//
ID   CO4A2_HUMAN             Reviewed;        1712 AA.
AC   P08572; Q14052; Q548C3; Q5VZA9; Q66K23;
DE   RecName: Full=Collagen alpha-2(IV) chain;
DE   Contains:
DE     RecName: Full=Canstatin;
DE   Flags: Precursor;
GN   Name=COL4A2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:Ensembl.
//
ID   CO4A3_HUMAN             Reviewed;        1670 AA.
AC   Q01955; Q53QQ1; Q53R14; Q53RW8; Q9BQT2; Q9NYC4; Q9UDJ9; Q9UDK9;
AC   Q9UDL0; Q9UDL1;
DE   RecName: Full=Collagen alpha-3(IV) chain;
DE   AltName: Full=Goodpasture antigen;
DE   Contains:
DE     RecName: Full=Tumstatin;
DE   Flags: Precursor;
GN   Name=COL4A3;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; IDA:UniProtKB.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0072577; P:endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; NAS:GOC.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   CO4A4_HUMAN             Reviewed;        1690 AA.
AC   P53420; A8MTZ1; Q53RW9; Q53S42; Q53WR1;
DE   RecName: Full=Collagen alpha-4(IV) chain;
DE   Flags: Precursor;
GN   Name=COL4A4;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.
//
ID   CO4A5_HUMAN             Reviewed;        1685 AA.
AC   P29400; Q16006; Q16126; Q6LD84; Q7Z700; Q9NUB7;
DE   RecName: Full=Collagen alpha-5(IV) chain;
DE   Flags: Precursor;
GN   Name=COL4A5;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
//
ID   CO4A6_HUMAN             Reviewed;        1691 AA.
AC   Q14031; Q12823; Q14053; Q5JYH6; Q5JYH8; Q9NQM5; Q9NTX3; Q9UJ76;
AC   Q9UMG6; Q9Y4L4;
DE   RecName: Full=Collagen alpha-6(IV) chain;
DE   Flags: Precursor;
GN   Name=COL4A6;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   CO4A_HUMAN              Reviewed;        1744 AA.
AC   P0C0L4; A6H8M8; A6NHJ5; A7E2V2; B0QZR6; B0V2C8; B2RUT6; B7ZVZ6;
AC   P01028; P78445; Q13160; Q13906; Q14033; Q14835; Q4LE82; Q5JNX2;
AC   Q5JQM8; Q6P4R1; Q6U2E5; Q6U2E8; Q6U2F0; Q6U2F3; Q6U2F4; Q6U2F6;
AC   Q6U2F8; Q6U2G0; Q96EG2; Q96SA8; Q9NPK5; Q9UIP5;
DE   RecName: Full=Complement C4-A;
DE   AltName: Full=Acidic complement C4;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2;
DE   Contains:
DE     RecName: Full=Complement C4 beta chain;
DE   Contains:
DE     RecName: Full=Complement C4-A alpha chain;
DE   Contains:
DE     RecName: Full=C4a anaphylatoxin;
DE   Contains:
DE     RecName: Full=C4b-A;
DE   Contains:
DE     RecName: Full=C4d-A;
DE   Contains:
DE     RecName: Full=Complement C4 gamma chain;
DE   Flags: Precursor;
GN   Name=C4A; Synonyms=CO4, CPAMD2;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO4B_HUMAN              Reviewed;        1744 AA.
AC   P0C0L5; A2BHY4; P01028; P78445; Q13160; Q13906; Q14033; Q14835;
AC   Q6U2E9; Q6U2G1; Q6U2I5; Q6U2L1; Q6U2L7; Q6U2L9; Q6U2M5; Q6VCV8;
AC   Q96SA7; Q9NPK5; Q9UIP5;
DE   RecName: Full=Complement C4-B;
DE   AltName: Full=Basic complement C4;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3;
DE   Contains:
DE     RecName: Full=Complement C4 beta chain;
DE   Contains:
DE     RecName: Full=Complement C4-B alpha chain;
DE   Contains:
DE     RecName: Full=C4a anaphylatoxin;
DE   Contains:
DE     RecName: Full=C4b-B;
DE   Contains:
DE     RecName: Full=C4d-B;
DE   Contains:
DE     RecName: Full=Complement C4 gamma chain;
DE   Flags: Precursor;
GN   Name=C4B; Synonyms=CO4, CPAMD3;
GN   and
GN   Name=C4B_2;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO5A1_HUMAN             Reviewed;        1838 AA.
AC   P20908; Q15094; Q5SUX4;
DE   RecName: Full=Collagen alpha-1(V) chain;
DE   Flags: Precursor;
GN   Name=COL5A1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:Ensembl.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0032964; P:collagen biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:UniProtKB.
DR   GO; GO:0043206; P:extracellular fibril organization; IMP:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0048592; P:eye morphogenesis; IMP:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0045112; P:integrin biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0051128; P:regulation of cellular component organization; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IMP:UniProtKB.
DR   GO; GO:0035989; P:tendon development; IEA:Ensembl.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IMP:UniProtKB.
//
ID   CO5A2_HUMAN             Reviewed;        1499 AA.
AC   P05997; P78440; Q13908; Q53WR4; Q59GR4; Q6LDJ5; Q7KZ55; Q86XF6;
AC   Q96QB0; Q96QB3;
DE   RecName: Full=Collagen alpha-2(V) chain;
DE   Flags: Precursor;
GN   Name=COL5A2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0048592; P:eye morphogenesis; IMP:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IMP:UniProtKB.
//
ID   CO5A3_HUMAN             Reviewed;        1745 AA.
AC   P25940; Q9NZQ6;
DE   RecName: Full=Collagen alpha-3(V) chain;
DE   Flags: Precursor;
GN   Name=COL5A3;
DR   GO; GO:0005518; F:collagen binding; NAS:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; NAS:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0043588; P:skin development; NAS:UniProtKB.
//
ID   CO5_HUMAN               Reviewed;        1676 AA.
AC   P01031; Q14CJ0; Q27I61;
DE   RecName: Full=Complement C5;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4;
DE   Contains:
DE     RecName: Full=Complement C5 beta chain;
DE   Contains:
DE     RecName: Full=Complement C5 alpha chain;
DE   Contains:
DE     RecName: Full=C5a anaphylatoxin;
DE   Contains:
DE     RecName: Full=Complement C5 alpha' chain;
DE   Flags: Precursor;
GN   Name=C5; Synonyms=CPAMD4;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002523; P:leukocyte migration involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0033602; P:negative regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0010760; P:negative regulation of macrophage chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IDA:BHF-UCL.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   CO6A1_HUMAN             Reviewed;        1028 AA.
AC   P12109; O00117; O00118; Q14040; Q14041; Q16258; Q7Z645; Q9BSA8;
DE   RecName: Full=Collagen alpha-1(VI) chain;
DE   Flags: Precursor;
GN   Name=COL6A1;
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:MGI.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0070208; P:protein heterotrimerization; IPI:MGI.
//
ID   CO6A2_HUMAN             Reviewed;        1019 AA.
AC   P12110; Q13909; Q13910; Q13911; Q14048; Q14049; Q16259; Q16597;
AC   Q6P0Q1; Q9UML3; Q9Y4S8;
DE   RecName: Full=Collagen alpha-2(VI) chain;
DE   Flags: Precursor;
GN   Name=COL6A2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0070208; P:protein heterotrimerization; IPI:MGI.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
//
ID   CO6A3_HUMAN             Reviewed;        3177 AA.
AC   P12111; A8MT30; B4E3U5; B7ZMJ7; E9PFQ6; E9PGQ9; Q16501; Q53QF4;
AC   Q53QF6;
DE   RecName: Full=Collagen alpha-3(VI) chain;
DE   Flags: Precursor;
GN   Name=COL6A3;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   CO6A5_HUMAN             Reviewed;        2615 AA.
AC   A8TX70; A9J6L2; A9J6L4; A9J6L6; A9J6L7; A9J6M0; A9J6M1; A9J6M2;
AC   B5MEA7; Q6ZW26; Q8NA36;
DE   RecName: Full=Collagen alpha-5(VI) chain;
DE   AltName: Full=Collagen alpha-1(XXIX) chain;
DE   AltName: Full=von Willebrand factor A domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=COL6A5; Synonyms=COL29A1, VWA4;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   CO6A6_HUMAN             Reviewed;        2263 AA.
AC   A6NMZ7; A7DZQ0; A7DZQ1; A7DZQ2; Q69YT0;
DE   RecName: Full=Collagen alpha-6(VI) chain;
DE   Flags: Precursor;
GN   Name=COL6A6;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   CO6_HUMAN               Reviewed;         934 AA.
AC   P13671;
DE   RecName: Full=Complement component C6;
DE   Flags: Precursor;
GN   Name=C6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:ProtInc.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001970; P:positive regulation of activation of membrane attack complex; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO7A1_HUMAN             Reviewed;        2944 AA.
AC   Q02388; Q14054; Q16507;
DE   RecName: Full=Collagen alpha-1(VII) chain;
DE   AltName: Full=Long-chain collagen;
DE            Short=LC collagen;
DE   Flags: Precursor;
GN   Name=COL7A1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   CO7_HUMAN               Reviewed;         843 AA.
AC   P10643; Q6P3T5; Q92489;
DE   RecName: Full=Complement component C7;
DE   Flags: Precursor;
GN   Name=C7;
DR   GO; GO:0006883; P:cellular sodium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006956; P:complement activation; TAS:ProtInc.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO8A1_HUMAN             Reviewed;         744 AA.
AC   P27658; D3DN42; Q53XI6; Q96D07;
DE   RecName: Full=Collagen alpha-1(VIII) chain;
DE   AltName: Full=Endothelial collagen;
DE   Contains:
DE     RecName: Full=Vastatin;
DE   Flags: Precursor;
GN   Name=COL8A1; Synonyms=C3orf7;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   CO8A2_HUMAN             Reviewed;         703 AA.
AC   P25067; Q5JV31; Q8TEJ5;
DE   RecName: Full=Collagen alpha-2(VIII) chain;
DE   AltName: Full=Endothelial collagen;
DE   Flags: Precursor;
GN   Name=COL8A2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
//
ID   CO8A_HUMAN              Reviewed;         584 AA.
AC   P07357; A2RUI4; A2RUI5; Q13668; Q9H130;
DE   RecName: Full=Complement component C8 alpha chain;
DE   AltName: Full=Complement component 8 subunit alpha;
DE   Flags: Precursor;
GN   Name=C8A;
DR   GO; GO:0006956; P:complement activation; IDA:MGI.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO8B_HUMAN              Reviewed;         591 AA.
AC   P07358; A1L4K7;
DE   RecName: Full=Complement component C8 beta chain;
DE   AltName: Full=Complement component 8 subunit beta;
DE   Flags: Precursor;
GN   Name=C8B;
DR   GO; GO:0006956; P:complement activation; TAS:ProtInc.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO8G_HUMAN              Reviewed;         202 AA.
AC   P07360; Q14CT8; Q14CU0; Q5SQ07;
DE   RecName: Full=Complement component C8 gamma chain;
DE   Flags: Precursor;
GN   Name=C8G;
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CO9A1_HUMAN             Reviewed;         921 AA.
AC   P20849; Q13699; Q13700; Q5TF52; Q6P467; Q96BM8; Q99225; Q9H151;
AC   Q9H152; Q9Y6P2; Q9Y6P3;
DE   RecName: Full=Collagen alpha-1(IX) chain;
DE   Flags: Precursor;
GN   Name=COL9A1;
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IC:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
//
ID   CO9A2_HUMAN             Reviewed;         689 AA.
AC   Q14055; B2RMP9;
DE   RecName: Full=Collagen alpha-2(IX) chain;
DE   Flags: Precursor;
GN   Name=COL9A2;
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IC:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   CO9A3_HUMAN             Reviewed;         684 AA.
AC   Q14050; Q13681; Q9H4G9; Q9UPE2;
DE   RecName: Full=Collagen alpha-3(IX) chain;
DE   Flags: Precursor;
GN   Name=COL9A3;
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; IC:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
//
ID   CO9_HUMAN               Reviewed;         559 AA.
AC   P02748;
DE   RecName: Full=Complement component C9;
DE   Contains:
DE     RecName: Full=Complement component C9a;
DE   Contains:
DE     RecName: Full=Complement component C9b;
DE   Flags: Precursor;
GN   Name=C9;
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019836; P:hemolysis by symbiont of host erythrocytes; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   COA1_HUMAN              Reviewed;         146 AA.
AC   Q9GZY4; A6NJU8; A8KAH8; Q9HAB7; Q9NVD2;
DE   RecName: Full=Cytochrome c oxidase assembly factor 1 homolog;
DE   AltName: Full=Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa;
GN   Name=COA1; Synonyms=C7orf44, MITRAC15;
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0033617; P:mitochondrial respiratory chain complex IV assembly; IMP:UniProtKB.
//
ID   COA3_HUMAN              Reviewed;         106 AA.
AC   Q9Y2R0; A8K498;
DE   RecName: Full=Cytochrome c oxidase assembly factor 3 homolog, mitochondrial;
DE   AltName: Full=Coiled-coil domain-containing protein 56;
DE   AltName: Full=Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa;
GN   Name=COA3; Synonyms=CCDC56, MITRAC12; ORFNames=HSPC009;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033617; P:mitochondrial respiratory chain complex IV assembly; IMP:UniProtKB.
DR   GO; GO:0070131; P:positive regulation of mitochondrial translation; IMP:UniProtKB.
//
ID   COA4_HUMAN              Reviewed;          87 AA.
AC   Q9NYJ1; B2RAA0; Q69YU4;
DE   RecName: Full=Cytochrome c oxidase assembly factor 4 homolog, mitochondrial;
DE   AltName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 8;
DE   AltName: Full=E2-induced gene 2 protein;
GN   Name=COA4; Synonyms=CHCHD8, E2IG2;
//
ID   COA5_HUMAN              Reviewed;          74 AA.
AC   Q86WW8;
DE   RecName: Full=Cytochrome c oxidase assembly factor 5;
GN   Name=COA5; Synonyms=C2orf64;
//
ID   COA6_HUMAN              Reviewed;         125 AA.
AC   Q5JTJ3; Q5JTJ2; Q5JTJ4; Q8TA88;
DE   RecName: Full=Cytochrome c oxidase assembly factor 6 homolog;
GN   Name=COA6; Synonyms=C1orf31;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   COA7_HUMAN              Reviewed;         231 AA.
AC   Q96BR5; Q0P6I7; Q9H9Z9;
DE   RecName: Full=Cytochrome c oxidase assembly factor 7;
DE   AltName: Full=Beta-lactamase hcp-like protein;
DE   AltName: Full=Respiratory chain assembly factor 1;
DE   AltName: Full=Sel1 repeat-containing protein 1;
GN   Name=COA7; Synonyms=C1orf163, RESA1, SELRC1;
//
ID   COAA1_HUMAN             Reviewed;         680 AA.
AC   Q03692; A1L4P2;
DE   RecName: Full=Collagen alpha-1(X) chain;
DE   Flags: Precursor;
GN   Name=COL10A1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   COAC_HUMAN              Reviewed;         204 AA.
AC   Q96CD2; Q96SX0; Q9HC17;
DE   RecName: Full=Phosphopantothenoylcysteine decarboxylase;
DE            Short=PPC-DC;
DE            EC=4.1.1.36;
DE   AltName: Full=CoaC;
GN   Name=PPCDC; Synonyms=COAC; ORFNames=MDS018, UNQ9365/PRO34154;
DR   GO; GO:0004633; F:phosphopantothenoylcysteine decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009108; P:coenzyme biosynthetic process; TAS:Reactome.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   COASY_HUMAN             Reviewed;         564 AA.
AC   Q13057; B2RA78; B4DLU0; Q6GS23; Q8NBM7; Q8NEW1; Q8WXD4; Q9NRM3;
DE   RecName: Full=Bifunctional coenzyme A synthase;
DE            Short=CoA synthase;
DE   AltName: Full=NBP;
DE   AltName: Full=POV-2;
DE   Includes:
DE     RecName: Full=Phosphopantetheine adenylyltransferase;
DE              EC=2.7.7.3;
DE     AltName: Full=Dephospho-CoA pyrophosphorylase;
DE     AltName: Full=Pantetheine-phosphate adenylyltransferase;
DE              Short=PPAT;
DE   Includes:
DE     RecName: Full=Dephospho-CoA kinase;
DE              Short=DPCK;
DE              EC=2.7.1.24;
DE     AltName: Full=Dephosphocoenzyme A kinase;
DE              Short=DPCOAK;
GN   Name=COASY; ORFNames=PSEC0106;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IDA:UniProtKB.
DR   GO; GO:0004595; F:pantetheine-phosphate adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009108; P:coenzyme biosynthetic process; TAS:Reactome.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   COAS1_HUMAN             Reviewed;          56 AA.
AC   Q5SY13;
DE   RecName: Full=Putative uncharacterized protein encoded by COL5A1-AS1;
DE   AltName: Full=COL5A1 antisense RNA 1;
DE   AltName: Full=COL5A1 antisense gene protein 1;
GN   Name=COL5A1-AS1; Synonyms=C9orf104;
//
ID   COBA1_HUMAN             Reviewed;        1806 AA.
AC   P12107; B1ASK7; D3DT73; E9PCU0; Q14034; Q149N0; Q9UIT4; Q9UIT5;
AC   Q9UIT6;
DE   RecName: Full=Collagen alpha-1(XI) chain;
DE   Flags: Precursor;
GN   Name=COL11A1; Synonyms=COLL6;
DR   GO; GO:0050840; F:extracellular matrix binding; NAS:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; NAS:UniProtKB.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0035989; P:tendon development; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   COBA2_HUMAN             Reviewed;        1736 AA.
AC   P13942; A6NLX2; E7ER90; Q07751; Q13271; Q13272; Q13273; Q5JP94;
AC   Q5SUI8; Q7Z6C3; Q99866; Q9UIP9;
DE   RecName: Full=Collagen alpha-2(XI) chain;
DE   Flags: Precursor;
GN   Name=COL11A2;
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; IMP:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IDA:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060021; P:palate development; IMP:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0060023; P:soft palate development; IMP:UniProtKB.
//
ID   COBL1_HUMAN             Reviewed;        1204 AA.
AC   Q53SF7; A6NMZ3; Q6IQ33; Q7Z3I6; Q9BRH4; Q9UG88; Q9Y2I3;
DE   RecName: Full=Cordon-bleu protein-like 1;
GN   Name=COBLL1; Synonyms=KIAA0977;
//
ID   COBL_HUMAN              Reviewed;        1261 AA.
AC   O75128; A4D257; A7E2B0; B7ZLW9; B9EGF8; Q2T9J3; Q504Y4; Q86XA7;
AC   Q8N304; Q8TCM1;
DE   RecName: Full=Protein cordon-bleu;
GN   Name=COBL; Synonyms=KIAA0633;
DR   GO; GO:0003785; F:actin monomer binding; ISS:BHF-UCL.
DR   GO; GO:0051639; P:actin filament network formation; ISS:BHF-UCL.
DR   GO; GO:0030041; P:actin filament polymerization; ISS:BHF-UCL.
DR   GO; GO:0048669; P:collateral sprouting in absence of injury; ISS:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; ISS:BHF-UCL.
DR   GO; GO:0000578; P:embryonic axis specification; ISS:BHF-UCL.
DR   GO; GO:0033504; P:floor plate development; ISS:BHF-UCL.
DR   GO; GO:0001889; P:liver development; ISS:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; ISS:BHF-UCL.
DR   GO; GO:0030903; P:notochord development; ISS:BHF-UCL.
DR   GO; GO:1900006; P:positive regulation of dendrite development; ISS:BHF-UCL.
DR   GO; GO:0001757; P:somite specification; ISS:BHF-UCL.
//
ID   COCA1_HUMAN             Reviewed;        3063 AA.
AC   Q99715; O43853; Q15955; Q5VYK1; Q5VYK2; Q71UR3; Q99716;
DE   RecName: Full=Collagen alpha-1(XII) chain;
DE   Flags: Precursor;
GN   Name=COL12A1; Synonyms=COL12A1L;
DR   GO; GO:0030020; F:extracellular matrix structural constituent conferring tensile strength; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; NAS:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   COCH_HUMAN              Reviewed;         550 AA.
AC   O43405; A8K9K9; D3DS84;
DE   RecName: Full=Cochlin;
DE   AltName: Full=COCH-5B2;
DE   Flags: Precursor;
GN   Name=COCH; Synonyms=COCH5B2; ORFNames=UNQ257/PRO294;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   CODA1_HUMAN             Reviewed;         717 AA.
AC   Q5TAT6; A6NFR5; B9EGD2; E7EWL8; Q13992; Q13993; Q13994; Q13995;
AC   Q13996; Q5TAT4; Q5TAT5; Q7KZ33; Q7KZ49; Q99228; Q9NQ52;
DE   RecName: Full=Collagen alpha-1(XIII) chain;
DE   AltName: Full=COLXIIIA1;
GN   Name=COL13A1;
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEP:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IPI:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0001958; P:endochondral ossification; ISS:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; ISS:UniProtKB.
//
ID   COE1_HUMAN              Reviewed;         591 AA.
AC   Q9UH73; Q8IW11;
DE   RecName: Full=Transcription factor COE1;
DE            Short=O/E-1;
DE            Short=OE-1;
DE   AltName: Full=Early B-cell factor;
GN   Name=EBF1; Synonyms=COE1, EBF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   COE2_HUMAN              Reviewed;         575 AA.
AC   Q9HAK2; A0PJM4; A6NMF7; Q6DK36; Q6IS86; Q6ISA4;
DE   RecName: Full=Transcription factor COE2;
DE   AltName: Full=Early B-cell factor 2;
DE            Short=EBF-2;
GN   Name=EBF2; Synonyms=COE2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   COE3_HUMAN              Reviewed;         596 AA.
AC   Q9H4W6; A0AUY1; Q5T6H9; Q9H4W5;
DE   RecName: Full=Transcription factor COE3;
DE   AltName: Full=Early B-cell factor 3;
DE            Short=EBF-3;
DE   AltName: Full=Olf-1/EBF-like 2;
DE            Short=O/E-2;
DE            Short=OE-2;
GN   Name=EBF3; Synonyms=COE3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   COE4_HUMAN              Reviewed;         602 AA.
AC   Q9BQW3; Q1MTP7; Q5JY53; Q9NUB6; Q9P2A6;
DE   RecName: Full=Transcription factor COE4;
DE   AltName: Full=Early B-cell factor 4;
DE            Short=EBF-4;
DE   AltName: Full=Olf-1/EBF-like 4;
DE            Short=O/E-4;
DE            Short=OE-4;
GN   Name=EBF4; Synonyms=COE4, KIAA1442;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   COEA1_HUMAN             Reviewed;        1796 AA.
AC   Q05707; B2RU07; O00260; O00261; O00262; Q05708; Q5XJ18; Q96C67;
AC   Q9UDF6;
DE   RecName: Full=Collagen alpha-1(XIV) chain;
DE   AltName: Full=Undulin;
DE   Flags: Precursor;
GN   Name=COL14A1; Synonyms=UND;
DR   GO; GO:0005518; F:collagen binding; NAS:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; NAS:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0061050; P:regulation of cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0003229; P:ventricular cardiac muscle tissue development; IEA:Ensembl.
//
ID   COF1_HUMAN              Reviewed;         166 AA.
AC   P23528; B3KUQ1; Q53Y87; Q9UCA2;
DE   RecName: Full=Cofilin-1;
DE   AltName: Full=18 kDa phosphoprotein;
DE            Short=p18;
DE   AltName: Full=Cofilin, non-muscle isoform;
GN   Name=CFL1; Synonyms=CFL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0030042; P:actin filament depolymerization; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0045792; P:negative regulation of cell size; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0001842; P:neural fold formation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
//
ID   COF2_HUMAN              Reviewed;         166 AA.
AC   Q9Y281; G3V5P4;
DE   RecName: Full=Cofilin-2;
DE   AltName: Full=Cofilin, muscle isoform;
GN   Name=CFL2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030042; P:actin filament depolymerization; IEA:InterPro.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; IMP:UniProt.
//
ID   COFA1_HUMAN             Reviewed;        1388 AA.
AC   P39059; Q5T6J4; Q9UDC5; Q9Y4W4;
DE   RecName: Full=Collagen alpha-1(XV) chain;
DE   Contains:
DE     RecName: Full=Restin;
DE     AltName: Full=Endostatin-XV;
DE     AltName: Full=Related to endostatin;
DE     AltName: Full=Restin-I;
DE   Contains:
DE     RecName: Full=Restin-2;
DE     AltName: Full=Restin-II;
DE   Contains:
DE     RecName: Full=Restin-3;
DE     AltName: Full=Restin-III;
DE   Contains:
DE     RecName: Full=Restin-4;
DE     AltName: Full=Restin-IV;
DE   Flags: Precursor;
GN   Name=COL15A1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IC:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IC:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   COG1_HUMAN              Reviewed;         980 AA.
AC   Q8WTW3; Q9NPV9; Q9P2G6;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 1;
DE            Short=COG complex subunit 1;
DE   AltName: Full=Component of oligomeric Golgi complex 1;
GN   Name=COG1; Synonyms=KIAA1381, LDLB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007030; P:Golgi organization; NAS:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   COG2_HUMAN              Reviewed;         738 AA.
AC   Q14746; Q86U99;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 2;
DE            Short=COG complex subunit 2;
DE   AltName: Full=Component of oligomeric Golgi complex 2;
DE   AltName: Full=Low density lipoprotein receptor defect C-complementing protein;
GN   Name=COG2; Synonyms=LDLC;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   COG3_HUMAN              Reviewed;         828 AA.
AC   Q96JB2; B2RAW5; Q5VT70; Q8IXX4; Q9BZ92;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 3;
DE            Short=COG complex subunit 3;
DE   AltName: Full=Component of oligomeric Golgi complex 3;
DE   AltName: Full=Vesicle-docking protein SEC34 homolog;
DE   AltName: Full=p94;
GN   Name=COG3; Synonyms=SEC34;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IMP:UniProtKB.
DR   GO; GO:0033365; P:protein localization to organelle; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.
//
ID   COG5_HUMAN              Reviewed;         839 AA.
AC   Q9UP83; A4D0R6; A4D0R7; O14555; O95008; Q6NUL5;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 5;
DE            Short=COG complex subunit 5;
DE   AltName: Full=13S Golgi transport complex 90 kDa subunit;
DE            Short=GTC-90;
DE   AltName: Full=Component of oligomeric Golgi complex 5;
DE   AltName: Full=Golgi transport complex 1;
GN   Name=COG5; Synonyms=GOLTC1, GTC90;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   COG4_HUMAN              Reviewed;         785 AA.
AC   Q9H9E3; B4DMN8; C9JS23; Q96D40; Q9BRF0; Q9BVZ2; Q9H5Y4; Q9Y3W3;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 4;
DE            Short=COG complex subunit 4;
DE   AltName: Full=Component of oligomeric Golgi complex 4;
GN   Name=COG4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0048213; P:Golgi vesicle prefusion complex stabilization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.
//
ID   COG6_HUMAN              Reviewed;         657 AA.
AC   Q9Y2V7; Q5T0U1; Q6AI19; Q86V49; Q9ULT5;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=COG6; Synonyms=KIAA1134;
DR   GO; GO:0070085; P:glycosylation; IMP:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   COG7_HUMAN              Reviewed;         770 AA.
AC   P83436; Q6UWU7;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 7;
DE            Short=COG complex subunit 7;
DE   AltName: Full=Component of oligomeric Golgi complex 7;
GN   Name=COG7; ORFNames=UNQ3082/PRO10013;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; IMP:UniProtKB.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IMP:UniProtKB.
DR   GO; GO:0033365; P:protein localization to organelle; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.
//
ID   COG8_HUMAN              Reviewed;         612 AA.
AC   Q96MW5; Q0VAK2; Q8WVV6; Q9H6F8;
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 8;
DE            Short=COG complex subunit 8;
DE   AltName: Full=Component of oligomeric Golgi complex 8;
GN   Name=COG8;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   COGA1_HUMAN             Reviewed;        1604 AA.
AC   Q07092; Q16593; Q59F89; Q71RG9;
DE   RecName: Full=Collagen alpha-1(XVI) chain;
DE   Flags: Precursor;
GN   Name=COL16A1; ORFNames=FP1572;
DR   GO; GO:0005178; F:integrin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:UniProtKB.
//
ID   COHA1_HUMAN             Reviewed;        1497 AA.
AC   Q9UMD9; Q02802; Q5JV36; Q99018; Q9NQK9; Q9UC14;
DE   RecName: Full=Collagen alpha-1(XVII) chain;
DE   AltName: Full=180 kDa bullous pemphigoid antigen 2;
DE   AltName: Full=Bullous pemphigoid antigen 2;
DE   Contains:
DE     RecName: Full=120 kDa linear IgA disease antigen;
DE     AltName: Full=120 kDa linear IgA dermatosis antigen;
DE     AltName: Full=Linear IgA disease antigen 1;
DE              Short=LAD-1;
DE   Contains:
DE     RecName: Full=97 kDa linear IgA disease antigen;
DE     AltName: Full=97 kDa linear IgA bullous dermatosis antigen;
DE              Short=97 kDa LAD antigen;
DE              Short=97-LAD;
DE     AltName: Full=Linear IgA bullous disease antigen of 97 kDa;
DE              Short=LABD97;
GN   Name=COL17A1; Synonyms=BP180, BPAG2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
//
ID   COIA1_HUMAN             Reviewed;        1754 AA.
AC   P39060; A8MVI4; Q58EX6; Q6RZ39; Q6RZ40; Q6RZ41; Q8N4S4; Q8WXI5;
AC   Q96T70; Q9UK38; Q9Y6Q7; Q9Y6Q8;
DE   RecName: Full=Collagen alpha-1(XVIII) chain;
DE   Contains:
DE     RecName: Full=Endostatin;
DE   Flags: Precursor;
GN   Name=COL18A1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051599; P:response to hydrostatic pressure; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   COIL_HUMAN              Reviewed;         576 AA.
AC   P38432; B2R931;
DE   RecName: Full=Coilin;
DE   AltName: Full=p80-coilin;
GN   Name=COIL; Synonyms=CLN80;
DR   GO; GO:0015036; F:disulfide oxidoreductase activity; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
//
ID   COJA1_HUMAN             Reviewed;        1142 AA.
AC   Q14993; Q00559; Q05850; Q12885; Q13676; Q14DH1; Q5JUF0; Q5T424;
AC   Q9H572; Q9NPZ2; Q9NQP2;
DE   RecName: Full=Collagen alpha-1(XIX) chain;
DE   AltName: Full=Collagen alpha-1(Y) chain;
DE   Flags: Precursor;
GN   Name=COL19A1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   COKA1_HUMAN             Reviewed;        1284 AA.
AC   Q9P218; Q4VXQ4; Q6PI59; Q8WUT2; Q96CY9; Q9BQU6; Q9BQU7;
DE   RecName: Full=Collagen alpha-1(XX) chain;
DE   Flags: Precursor;
GN   Name=COL20A1; Synonyms=KIAA1510;
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COL10_HUMAN             Reviewed;         277 AA.
AC   Q9Y6Z7; Q3SYH6; Q6UW19;
DE   RecName: Full=Collectin-10;
DE   AltName: Full=Collectin liver protein 1;
DE            Short=CL-L1;
DE   AltName: Full=Collectin-34;
DE            Short=CL-34;
DE   Flags: Precursor;
GN   Name=COLEC10; Synonyms=CLL1; ORFNames=UNQ366/PRO702;
DR   GO; GO:0005537; F:mannose binding; TAS:ProtInc.
//
ID   COL11_HUMAN             Reviewed;         271 AA.
AC   Q9BWP8; A1IGE4; A1IGE5; A1IGE6; A7VJJ2; A7VJJ3; A7VJJ4; A7VJJ5;
AC   B2R9M5; B4E1G0; J3KQY9; Q5CZ85; Q7Z6N1;
DE   RecName: Full=Collectin-11;
DE   AltName: Full=Collectin kidney protein 1;
DE            Short=CL-K1;
DE   Flags: Precursor;
GN   Name=COLEC11; ORFNames=UNQ596/PRO1182;
DR   GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
DR   GO; GO:0032502; P:developmental process; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   COL12_HUMAN             Reviewed;         742 AA.
AC   Q5KU26; Q6P9F2; Q8TCR2; Q8WZA4; Q9BY85; Q9BYH7;
DE   RecName: Full=Collectin-12;
DE   AltName: Full=Collectin placenta protein 1;
DE            Short=CL-P1;
DE            Short=hCL-P1;
DE   AltName: Full=Nurse cell scavenger receptor 2;
DE   AltName: Full=Scavenger receptor class A member 4;
DE   AltName: Full=Scavenger receptor with C-type lectin;
GN   Name=COLEC12; Synonyms=CLP1, NSR2, SCARA4, SRCL;
DR   GO; GO:0005534; F:galactose binding; NAS:UniProtKB.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005044; F:scavenger receptor activity; TAS:UniProtKB.
DR   GO; GO:0008329; F:signaling pattern recognition receptor activity; IDA:UniProtKB.
DR   GO; GO:0009756; P:carbohydrate mediated signaling; NAS:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; IDA:GOC.
DR   GO; GO:0006910; P:phagocytosis, recognition; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; NAS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:GOC.
//
ID   COLA1_HUMAN             Reviewed;         957 AA.
AC   Q96P44; A6NIX5; B2R8J9; Q49A51; Q71RF4; Q8WXV8; Q9H0V3;
DE   RecName: Full=Collagen alpha-1(XXI) chain;
DE   Flags: Precursor;
GN   Name=COL21A1; Synonyms=COL1AL; ORFNames=FP633;
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COLC1_HUMAN             Reviewed;         124 AA.
AC   Q6ZS62;
DE   RecName: Full=Colorectal cancer-associated protein 1;
GN   Name=COLCA1; Synonyms=C11orf92;
//
ID   COLC2_HUMAN             Reviewed;         154 AA.
AC   A8K830; E9PMJ8; Q2TBJ3;
DE   RecName: Full=Colorectal cancer-associated protein 2;
DE   AltName: Full=Cancer susceptibility candidate protein 13;
GN   Name=COLCA2; Synonyms=C11orf93, CASC13;
//
ID   COLI_HUMAN              Reviewed;         267 AA.
AC   P01189; P78442; Q53T23; Q9UD39; Q9UD40;
DE   RecName: Full=Pro-opiomelanocortin;
DE            Short=POMC;
DE   AltName: Full=Corticotropin-lipotropin;
DE   Contains:
DE     RecName: Full=NPP;
DE   Contains:
DE     RecName: Full=Melanotropin gamma;
DE     AltName: Full=Gamma-MSH;
DE   Contains:
DE     RecName: Full=Potential peptide;
DE   Contains:
DE     RecName: Full=Corticotropin;
DE     AltName: Full=Adrenocorticotropic hormone;
DE              Short=ACTH;
DE   Contains:
DE     RecName: Full=Melanotropin alpha;
DE     AltName: Full=Alpha-MSH;
DE   Contains:
DE     RecName: Full=Corticotropin-like intermediary peptide;
DE              Short=CLIP;
DE   Contains:
DE     RecName: Full=Lipotropin beta;
DE     AltName: Full=Beta-LPH;
DE   Contains:
DE     RecName: Full=Lipotropin gamma;
DE     AltName: Full=Gamma-LPH;
DE   Contains:
DE     RecName: Full=Melanotropin beta;
DE     AltName: Full=Beta-MSH;
DE   Contains:
DE     RecName: Full=Beta-endorphin;
DE   Contains:
DE     RecName: Full=Met-enkephalin;
DE   Flags: Precursor;
GN   Name=POMC;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005179; F:hormone activity; IMP:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IMP:UniProtKB.
DR   GO; GO:0070996; F:type 1 melanocortin receptor binding; IDA:BHF-UCL.
DR   GO; GO:0031781; F:type 3 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031782; F:type 4 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; IMP:UniProtKB.
DR   GO; GO:0033059; P:cellular pigmentation; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IMP:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032098; P:regulation of appetite; IMP:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
//
ID   COLL1_HUMAN             Reviewed;         121 AA.
AC   A2RUU4; A7E2T6; B2RPE2; B5G4V2; B6ZDM9; Q5T9G1;
DE   RecName: Full=Colipase-like protein 1;
DE   Flags: Precursor;
GN   Name=CLPSL1; Synonyms=C6orf127;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
//
ID   COLL2_HUMAN             Reviewed;         100 AA.
AC   Q6UWE3; B0QZ45; Q5T9G3;
DE   RecName: Full=Colipase-like protein 2;
DE   Flags: Precursor;
GN   Name=CLPSL2; Synonyms=C6orf126; ORFNames=UNQ3045/PRO9861;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
//
ID   COLQ_HUMAN              Reviewed;         455 AA.
AC   Q9Y215; B3KY09; Q6DK18; Q6YH18; Q6YH19; Q6YH20; Q6YH21; Q9NP18;
AC   Q9NP19; Q9NP20; Q9NP21; Q9NP22; Q9NP23; Q9NP24; Q9UP88;
DE   RecName: Full=Acetylcholinesterase collagenic tail peptide;
DE   AltName: Full=AChE Q subunit;
DE   AltName: Full=Acetylcholinesterase-associated collagen;
DE   Flags: Precursor;
GN   Name=COLQ;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001507; P:acetylcholine catabolic process in synaptic cleft; TAS:ProtInc.
DR   GO; GO:0008105; P:asymmetric protein localization; TAS:ProtInc.
//
ID   COL_HUMAN               Reviewed;         112 AA.
AC   P04118; Q5T9G7; Q5U809;
DE   RecName: Full=Colipase;
DE   Flags: Precursor;
GN   Name=CLPS;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044241; P:lipid digestion; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COM1_HUMAN              Reviewed;         897 AA.
AC   Q99708; A6NKN2; A8K8W6; E7ETY1; O75371; Q8NHQ3;
DE   RecName: Full=DNA endonuclease RBBP8;
DE            EC=3.1.-.-;
DE   AltName: Full=CtBP-interacting protein;
DE            Short=CtIP;
DE   AltName: Full=Retinoblastoma-binding protein 8;
DE            Short=RBBP-8;
DE   AltName: Full=Retinoblastoma-interacting protein and myosin-like;
DE            Short=RIM;
DE   AltName: Full=Sporulation in the absence of SPO11 protein 2 homolog;
DE            Short=SAE2;
GN   Name=RBBP8; Synonyms=CTIP;
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0000014; F:single-stranded DNA endodeoxyribonuclease activity; IMP:UniProtKB.
DR   GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
DR   GO; GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IMP:GOC.
DR   GO; GO:0010792; P:DNA double-strand break processing involved in repair via single-strand annealing; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   COMA1_HUMAN             Reviewed;        1626 AA.
AC   Q8NFW1; B7ZMH0; C9K0G4; Q8IVT9;
DE   RecName: Full=Collagen alpha-1(XXII) chain;
DE   Flags: Precursor;
GN   Name=COL22A1;
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COMD2_HUMAN             Reviewed;         199 AA.
AC   Q86X83; Q9H3L5; Q9Y5V1;
DE   RecName: Full=COMM domain-containing protein 2;
GN   Name=COMMD2; ORFNames=HSPC042, My004;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   COMD3_HUMAN             Reviewed;         195 AA.
AC   Q9UBI1; D3DRU7; Q5T8Y9;
DE   RecName: Full=COMM domain-containing protein 3;
DE   AltName: Full=Protein Bup;
DE   AltName: Full=Protein PIL;
GN   Name=COMMD3; Synonyms=BUP, C10orf8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   COMD1_HUMAN             Reviewed;         190 AA.
AC   Q8N668; Q96GS0;
DE   RecName: Full=COMM domain-containing protein 1;
DE   AltName: Full=Protein Murr1;
GN   Name=COMMD1; Synonyms=C2orf5, MURR1;
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0055070; P:copper ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   COMD4_HUMAN             Reviewed;         199 AA.
AC   Q9H0A8; B2RBN4; Q7L637; Q9NX43;
DE   RecName: Full=COMM domain-containing protein 4;
GN   Name=COMMD4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   COMD5_HUMAN             Reviewed;         224 AA.
AC   Q9GZQ3; D3DWN7; Q9NVN6; Q9UHX5;
DE   RecName: Full=COMM domain-containing protein 5;
DE   AltName: Full=Hypertension-related calcium-regulated gene protein;
DE            Short=HCaRG;
GN   Name=COMMD5; ORFNames=HT002;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   COMD6_HUMAN             Reviewed;          85 AA.
AC   Q7Z4G1; A6NF28; B7ZLN0; Q5TBK4;
DE   RecName: Full=COMM domain-containing protein 6;
GN   Name=COMMD6; ORFNames=MSTP076;
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:MGI.
//
ID   COMD7_HUMAN             Reviewed;         200 AA.
AC   Q86VX2; A2BHJ2; B3KTZ2; Q5JYB0; Q96SI7; Q9BW53;
DE   RecName: Full=COMM domain-containing protein 7;
GN   Name=COMMD7; Synonyms=C20orf92;
DR   GO; GO:0051059; F:NF-kappaB binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
//
ID   COMD9_HUMAN             Reviewed;         198 AA.
AC   Q9P000; E9PAN2; Q96FI2; Q9H0R0;
DE   RecName: Full=COMM domain-containing protein 9;
GN   Name=COMMD9; ORFNames=HSPC166;
//
ID   COMD8_HUMAN             Reviewed;         183 AA.
AC   Q9NX08; Q8WUR4; Q9HC15;
DE   RecName: Full=COMM domain-containing protein 8;
GN   Name=COMMD8; ORFNames=MDS022;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   COMDA_HUMAN             Reviewed;         202 AA.
AC   Q9Y6G5; D3DT07; Q9P077;
DE   RecName: Full=COMM domain-containing protein 10;
GN   Name=COMMD10; ORFNames=HSPC305, PTD002;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   COMP_HUMAN              Reviewed;         757 AA.
AC   P49747; O14592; Q16388; Q16389; Q2NL86; Q8N4T2;
DE   RecName: Full=Cartilage oligomeric matrix protein;
DE            Short=COMP;
DE   AltName: Full=Thrombospondin-5;
DE            Short=TSP5;
DE   Flags: Precursor;
GN   Name=COMP;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0043395; F:heparan sulfate proteoglycan binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR   GO; GO:0060173; P:limb development; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   COMT_HUMAN              Reviewed;         271 AA.
AC   P21964; A8MPV9; Q6IB07; Q6ICE6;
DE   RecName: Full=Catechol O-methyltransferase;
DE            EC=2.1.1.6;
GN   Name=COMT;
DR   GuidetoPHARMACOLOGY; 2472; -.
DR   GO; GO:0016206; F:catechol O-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0008171; F:O-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0042420; P:dopamine catabolic process; IEA:Ensembl.
DR   GO; GO:0008210; P:estrogen metabolic process; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0048609; P:multicellular organismal reproductive process; IEA:Ensembl.
DR   GO; GO:0045963; P:negative regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0050668; P:positive regulation of homocysteine metabolic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CONA1_HUMAN             Reviewed;         540 AA.
AC   Q86Y22; Q8IVR4; Q9NT93;
DE   RecName: Full=Collagen alpha-1(XXIII) chain;
GN   Name=COL23A1;
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COOA1_HUMAN             Reviewed;        1714 AA.
AC   Q17RW2; C9J1X6; Q14BD7; Q59EX5; Q5VY50; Q7Z5L5;
DE   RecName: Full=Collagen alpha-1(XXIV) chain;
DE   Flags: Precursor;
GN   Name=COL24A1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COPA1_HUMAN             Reviewed;         654 AA.
AC   Q9BXS0; A8MPZ6; Q9BXR9;
DE   RecName: Full=Collagen alpha-1(XXV) chain;
DE   AltName: Full=Alzheimer disease amyloid-associated protein;
DE            Short=AMY;
DE   AltName: Full=CLAC-P;
DE   Contains:
DE     RecName: Full=Collagen-like Alzheimer amyloid plaque component;
DE              Short=CLAC;
GN   Name=COL25A1;
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COPA_HUMAN              Reviewed;        1224 AA.
AC   P53621; Q5T201; Q8IXZ9;
DE   RecName: Full=Coatomer subunit alpha;
DE   AltName: Full=Alpha-coat protein;
DE            Short=Alpha-COP;
DE   AltName: Full=HEP-COP;
DE            Short=HEPCOP;
DE   Contains:
DE     RecName: Full=Xenin;
DE     AltName: Full=Xenopsin-related peptide;
DE   Contains:
DE     RecName: Full=Proxenin;
GN   Name=COPA;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0030157; P:pancreatic juice secretion; IDA:MGI.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
//
ID   COPB2_HUMAN             Reviewed;         906 AA.
AC   P35606;
DE   RecName: Full=Coatomer subunit beta';
DE   AltName: Full=Beta'-coat protein;
DE            Short=Beta'-COP;
DE   AltName: Full=p102;
GN   Name=COPB2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
//
ID   COPB_HUMAN              Reviewed;         953 AA.
AC   P53618; D3DQX0; Q6GTT7; Q9NTK2; Q9UNW7;
DE   RecName: Full=Coatomer subunit beta;
DE   AltName: Full=Beta-coat protein;
DE            Short=Beta-COP;
GN   Name=COPB1; Synonyms=COPB; ORFNames=MSTP026;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   COPD_HUMAN              Reviewed;         511 AA.
AC   P48444; B4E1X2; E9PEU4; Q52M80;
DE   RecName: Full=Coatomer subunit delta;
DE   AltName: Full=Archain;
DE   AltName: Full=Delta-coat protein;
DE            Short=Delta-COP;
GN   Name=ARCN1; Synonyms=COPD;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0021691; P:cerebellar Purkinje cell layer maturation; IEA:Ensembl.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
//
ID   COPE_HUMAN              Reviewed;         308 AA.
AC   O14579; A6NE29; A6NKA3; O76097; Q6IBB8; Q9UGP6;
DE   RecName: Full=Coatomer subunit epsilon;
DE   AltName: Full=Epsilon-coat protein;
DE            Short=Epsilon-COP;
GN   Name=COPE;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
//
ID   COPG1_HUMAN             Reviewed;         874 AA.
AC   Q9Y678; A8K6M8; B3KMF6; Q54AC4;
DE   RecName: Full=Coatomer subunit gamma-1;
DE   AltName: Full=Gamma-1-coat protein;
DE            Short=Gamma-1-COP;
GN   Name=COPG1; Synonyms=COPG;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0051683; P:establishment of Golgi localization; ISS:BHF-UCL.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0072384; P:organelle transport along microtubule; ISS:BHF-UCL.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
//
ID   COPG2_HUMAN             Reviewed;         871 AA.
AC   Q9UBF2; A6NH74; Q54AC3; Q8WVW8;
DE   RecName: Full=Coatomer subunit gamma-2;
DE   AltName: Full=Gamma-2-coat protein;
DE            Short=Gamma-2-COP;
GN   Name=COPG2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
//
ID   COPRS_HUMAN             Reviewed;         184 AA.
AC   Q9NQ92; A6NP14; E1P656; Q96EF5; Q96P75;
DE   RecName: Full=Coordinator of PRMT5 and differentiation stimulator;
DE   AltName: Full=Cooperator of PRMT5;
DE   AltName: Full=Protein TTP1;
GN   Name=COPRS; Synonyms=C17orf79, COPR5;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043985; P:histone H4-R3 methylation; IDA:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   COPT1_HUMAN             Reviewed;         190 AA.
AC   O15431; A8K8Z6; Q53GR5; Q5T1M4;
DE   RecName: Full=High affinity copper uptake protein 1;
DE   AltName: Full=Copper transporter 1;
DE            Short=hCTR1;
DE   AltName: Full=Solute carrier family 31 member 1;
GN   Name=SLC31A1; Synonyms=COPT1, CTR1;
DR   GO; GO:0005375; F:copper ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006825; P:copper ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   COPT2_HUMAN             Reviewed;         143 AA.
AC   O15432;
DE   RecName: Full=Probable low affinity copper uptake protein 2;
DE   AltName: Full=Copper transporter 2;
DE            Short=hCTR2;
DE   AltName: Full=Solute carrier family 31 member 2;
GN   Name=SLC31A2; Synonyms=COPT2, CTR2;
DR   GO; GO:0005375; F:copper ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006825; P:copper ion transport; TAS:ProtInc.
//
ID   COPZ1_HUMAN             Reviewed;         177 AA.
AC   P61923; B4DHZ0; Q549N6; Q9Y3C3;
DE   RecName: Full=Coatomer subunit zeta-1;
DE   AltName: Full=Zeta-1-coat protein;
DE            Short=Zeta-1 COP;
GN   Name=COPZ1; Synonyms=COPZ; ORFNames=CGI-120, HSPC181;
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB.
//
ID   COPZ2_HUMAN             Reviewed;         210 AA.
AC   Q9P299;
DE   RecName: Full=Coatomer subunit zeta-2;
DE   AltName: Full=Zeta-2-coat protein;
DE            Short=Zeta-2 COP;
GN   Name=COPZ2;
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   COQ2_HUMAN              Reviewed;         371 AA.
AC   Q96H96; O95331; Q1JQ78; Q684R2;
DE   RecName: Full=4-hydroxybenzoate polyprenyltransferase, mitochondrial;
DE            EC=2.5.1.39;
DE   AltName: Full=COQ2 homolog;
DE            Short=hCOQ2;
DE   AltName: Full=Para-hydroxybenzoate--polyprenyltransferase;
DE            Short=PHB:polyprenyltransferase;
DE   Flags: Precursor;
GN   Name=COQ2; Synonyms=CL640;
DR   GO; GO:0002083; F:4-hydroxybenzoate decaprenyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047293; F:4-hydroxybenzoate nonaprenyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006071; P:glycerol metabolic process; IGI:UniProtKB.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IDA:UniProtKB.
//
ID   COQ3_HUMAN              Reviewed;         369 AA.
AC   Q9NZJ6; B3KPX0; Q5T061; Q6P4F0; Q8IXG6; Q96BG1; Q9H0N1;
DE   RecName: Full=Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial;
DE            EC=2.1.1.114;
DE   AltName: Full=2-polyprenyl-6-hydroxyphenol methylase;
DE            EC=2.1.1.222;
DE   AltName: Full=3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase;
DE            Short=DHHB methyltransferase;
DE            Short=DHHB-MT;
DE            Short=DHHB-MTase;
DE   AltName: Full=3-demethylubiquinone-10 3-methyltransferase;
DE            EC=2.1.1.64;
DE   AltName: Full=Dihydroxyhexaprenylbenzoate methyltransferase;
DE   Flags: Precursor;
GN   Name=COQ3; ORFNames=UG0215E05;
DR   GO; GO:0008425; F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008689; F:3-demethylubiquinone-9 3-O-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004395; F:hexaprenyldihydroxybenzoate methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008171; F:O-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006071; P:glycerol metabolic process; IGI:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IGI:UniProtKB.
//
ID   COQ4_HUMAN              Reviewed;         265 AA.
AC   Q9Y3A0; A8WBK8; B2R958; Q5T4B8; Q96EW4;
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial;
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 homolog;
DE   Flags: Precursor;
GN   Name=COQ4; ORFNames=CGI-92;
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   COQ5_HUMAN              Reviewed;         327 AA.
AC   Q5HYK3; B4DEJ4; Q32Q28; Q53HH0; Q96LV1; Q9BSP8;
DE   RecName: Full=2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial;
DE            EC=2.1.1.201;
DE   AltName: Full=Ubiquinone biosynthesis methyltransferase COQ5;
DE   Flags: Precursor;
GN   Name=COQ5;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; TAS:Reactome.
//
ID   COQ6_HUMAN              Reviewed;         468 AA.
AC   Q9Y2Z9; B7Z3K8; Q53GG6; Q86U30; Q96CA1; Q96CK2;
DE   RecName: Full=Ubiquinone biosynthesis monooxygenase COQ6;
DE            EC=1.14.13.-;
DE   AltName: Full=Coenzyme Q10 monooxygenase 6;
GN   Name=COQ6; ORFNames=CGI-10;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; TAS:Reactome.
//
ID   COQ7_HUMAN              Reviewed;         217 AA.
AC   Q99807; B2RDA9; Q9BTT7; Q9H0T5; Q9UEW5; Q9UNR5;
DE   RecName: Full=Ubiquinone biosynthesis protein COQ7 homolog;
DE   AltName: Full=Coenzyme Q biosynthesis protein 7 homolog;
DE   AltName: Full=Timing protein clk-1 homolog;
DE   Flags: Precursor;
GN   Name=COQ7;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001306; P:age-dependent response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IEA:Ensembl.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; TAS:Reactome.
//
ID   COQ9_HUMAN              Reviewed;         318 AA.
AC   O75208; A8K3L2; Q7L5V7; Q7Z5T6; Q8NBL4; Q9NTJ2; Q9P056;
DE   RecName: Full=Ubiquinone biosynthesis protein COQ9, mitochondrial;
DE   Flags: Precursor;
GN   Name=COQ9; Synonyms=C16orf49; ORFNames=HSPC326, PSEC0129;
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:Ensembl.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   COQA1_HUMAN             Reviewed;         441 AA.
AC   Q96A83; Q32M90;
DE   RecName: Full=Collagen alpha-1(XXVI) chain;
DE   AltName: Full=Alpha-1 type XXVI collagen;
DE   AltName: Full=EMI domain-containing protein 2;
DE   AltName: Full=Emilin and multimerin domain-containing protein 2;
DE            Short=Emu2;
DE   Flags: Precursor;
GN   Name=COL26A1; Synonyms=EMID2, EMU2;
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COR1A_HUMAN             Reviewed;         461 AA.
AC   P31146; B2RBL1; Q2YD73;
DE   RecName: Full=Coronin-1A;
DE   AltName: Full=Coronin-like protein A;
DE            Short=Clipin-A;
DE   AltName: Full=Coronin-like protein p57;
DE   AltName: Full=Tryptophan aspartate-containing coat protein;
DE            Short=TACO;
GN   Name=CORO1A; Synonyms=CORO1;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0008092; F:cytoskeletal protein binding; ISS:UniProtKB.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0030595; P:leukocyte chemotaxis; IBA:RefGenome.
DR   GO; GO:0051126; P:negative regulation of actin nucleation; IDA:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IMP:UniProtKB.
DR   GO; GO:0001845; P:phagolysosome assembly; IMP:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IBA:RefGenome.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0032796; P:uropod organization; IBA:RefGenome.
//
ID   COR1B_HUMAN             Reviewed;         489 AA.
AC   Q9BR76; B2RD45;
DE   RecName: Full=Coronin-1B;
DE   AltName: Full=Coronin-2;
GN   Name=CORO1B;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProt.
DR   GO; GO:0071933; F:Arp2/3 complex binding; IDA:UniProt.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0090135; P:actin filament branching; IDA:UniProt.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:UniProt.
DR   GO; GO:0016477; P:cell migration; IDA:UniProt.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; IDA:UniProt.
DR   GO; GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; IDA:UniProt.
DR   GO; GO:2000394; P:positive regulation of lamellipodium morphogenesis; IDA:UniProt.
DR   GO; GO:1902463; P:protein localization to cell leading edge; IDA:UniProt.
DR   GO; GO:0031529; P:ruffle organization; IDA:UniProt.
DR   GO; GO:0042060; P:wound healing; IDA:UniProt.
//
ID   COR1C_HUMAN             Reviewed;         474 AA.
AC   Q9ULV4; A7MAP0; A7MAP1; B3KU12; Q9NSK5;
DE   RecName: Full=Coronin-1C;
DE   AltName: Full=Coronin-3;
DE   AltName: Full=hCRNN4;
GN   Name=CORO1C; Synonyms=CRN2, CRNN4;
DR   GO; GO:0051015; F:actin filament binding; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0006909; P:phagocytosis; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   COR2A_HUMAN             Reviewed;         525 AA.
AC   Q92828; Q5TBR5; Q92829; Q9BWS5;
DE   RecName: Full=Coronin-2A;
DE   AltName: Full=IR10;
DE   AltName: Full=WD repeat-containing protein 2;
GN   Name=CORO2A; Synonyms=IR10, WDR2;
DR   GO; GO:0051015; F:actin filament binding; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
//
ID   COR2B_HUMAN             Reviewed;         480 AA.
AC   Q9UQ03; A8K0W3; O94767; Q8TAN1;
DE   RecName: Full=Coronin-2B;
DE   AltName: Full=Coronin-like protein C;
DE            Short=Clipin-C;
DE   AltName: Full=Protein FC96;
GN   Name=CORO2B; Synonyms=KIAA0925;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
//
ID   CORA1_HUMAN             Reviewed;        1860 AA.
AC   Q8IZC6; Q66K43; Q96JF7;
DE   RecName: Full=Collagen alpha-1(XXVII) chain;
DE   Flags: Precursor;
GN   Name=COL27A1; Synonyms=KIAA1870;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   CORIN_HUMAN             Reviewed;        1042 AA.
AC   Q9Y5Q5; B0ZBE3; Q2TBD2; Q4W5E5; Q4W5G6; Q9UHY2;
DE   RecName: Full=Atrial natriuretic peptide-converting enzyme;
DE            EC=3.4.21.-;
DE   AltName: Full=Corin;
DE   AltName: Full=Heart-specific serine proteinase ATC2;
DE   AltName: Full=Pro-ANP-converting enzyme;
DE   AltName: Full=Transmembrane protease serine 10;
DE   Contains:
DE     RecName: Full=Atrial natriuretic peptide-converting enzyme, N-terminal propeptide;
DE   Contains:
DE     RecName: Full=Atrial natriuretic peptide-converting enzyme, activated protease fragment;
DE   Contains:
DE     RecName: Full=Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment;
DE   Contains:
DE     RecName: Full=Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment;
DE   Contains:
DE     RecName: Full=Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment;
GN   Name=CORIN; Synonyms=CRN, TMPRSS10;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0070008; F:serine-type exopeptidase activity; IEA:InterPro.
DR   GO; GO:0007565; P:female pregnancy; IMP:UniProtKB.
DR   GO; GO:0016486; P:peptide hormone processing; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:GOC.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0035813; P:regulation of renal sodium excretion; ISS:UniProtKB.
DR   GO; GO:0003050; P:regulation of systemic arterial blood pressure by atrial natriuretic peptide; IMP:UniProtKB.
//
ID   CORO6_HUMAN             Reviewed;         472 AA.
AC   Q6QEF8; B3KU26; Q71MF3; Q8WYH7; Q96K02;
DE   RecName: Full=Coronin-6;
DE   AltName: Full=Coronin-like protein E;
DE            Short=Clipin-E;
GN   Name=CORO6; ORFNames=PP1009, PP1782, PP1881;
DR   GO; GO:0051015; F:actin filament binding; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
//
ID   CORO7_HUMAN             Reviewed;         925 AA.
AC   P57737; B4DFD6; B4DL18; I3L416; Q17RK4;
DE   RecName: Full=Coronin-7;
DE            Short=Crn7;
DE   AltName: Full=70 kDa WD repeat tumor rejection antigen homolog;
GN   Name=CORO7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CORT_HUMAN              Reviewed;         105 AA.
AC   O00230; Q5T6G0; Q6UX11;
DE   RecName: Full=Cortistatin;
DE   Contains:
DE     RecName: Full=Cortistatin-29;
DE   Contains:
DE     RecName: Full=Cortistatin-17;
DE   Flags: Precursor;
GN   Name=CORT; ORFNames=UNQ307/PRO350;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IDA:UniProtKB.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
//
ID   COSA1_HUMAN             Reviewed;        1125 AA.
AC   Q2UY09; A4D101; A4D106; A4D107; A8MVR2; B9EGX9; Q2UY07; Q2UY08;
DE   RecName: Full=Collagen alpha-1(XXVIII) chain;
DE   Flags: Precursor;
GN   Name=COL28A1; Synonyms=COL28;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   COT1_HUMAN              Reviewed;         423 AA.
AC   P10589;
DE   RecName: Full=COUP transcription factor 1;
DE            Short=COUP-TF1;
DE   AltName: Full=COUP transcription factor I;
DE            Short=COUP-TF I;
DE   AltName: Full=Nuclear receptor subfamily 2 group F member 1;
DE   AltName: Full=V-erbA-related protein 3;
DE            Short=EAR-3;
GN   Name=NR2F1; Synonyms=EAR3, ERBAL3, TFCOUP1;
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0044323; F:retinoic acid-responsive element binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   COT2_HUMAN              Reviewed;         414 AA.
AC   P24468; B4DQJ2; B6ZGU1; Q03754; Q3KQR7;
DE   RecName: Full=COUP transcription factor 2;
DE            Short=COUP-TF2;
DE   AltName: Full=Apolipoprotein A-I regulatory protein 1;
DE            Short=ARP-1;
DE   AltName: Full=COUP transcription factor II;
DE            Short=COUP-TF II;
DE   AltName: Full=Nuclear receptor subfamily 2 group F member 2;
GN   Name=NR2F2; Synonyms=ARP1, TFCOUP2;
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0060173; P:limb development; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009956; P:radial pattern formation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0060849; P:regulation of transcription involved in lymphatic endothelial cell fate commitment; IMP:BHF-UCL.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
//
ID   COTL1_HUMAN             Reviewed;         142 AA.
AC   Q14019; B2RDU3; D3DUL9; Q86XM5;
DE   RecName: Full=Coactosin-like protein;
GN   Name=COTL1; Synonyms=CLP;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050832; P:defense response to fungus; IEA:Ensembl.
//
ID   COX10_HUMAN             Reviewed;         443 AA.
AC   Q12887; B2R6U5; O15334; Q969F7;
DE   RecName: Full=Protoheme IX farnesyltransferase, mitochondrial;
DE            EC=2.5.1.-;
DE   AltName: Full=Heme O synthase;
DE   Flags: Precursor;
GN   Name=COX10;
DR   GO; GO:0004311; F:farnesyltranstransferase activity; TAS:ProtInc.
DR   GO; GO:0008495; F:protoheme IX farnesyltransferase activity; IEA:InterPro.
DR   GO; GO:0009060; P:aerobic respiration; IEA:Ensembl.
DR   GO; GO:0045333; P:cellular respiration; IGI:HGNC.
DR   GO; GO:0006784; P:heme a biosynthetic process; IMP:HGNC.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:Reactome.
DR   GO; GO:0048034; P:heme O biosynthetic process; IEA:InterPro.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IC:HGNC.
DR   GO; GO:0000266; P:mitochondrial fission; IEA:Ensembl.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; IMP:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX11_HUMAN             Reviewed;         276 AA.
AC   Q9Y6N1; D3DTY5; I3L220; Q6FHB7; Q9BRX0; Q9UME8;
DE   RecName: Full=Cytochrome c oxidase assembly protein COX11, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX11;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0033132; P:negative regulation of glucokinase activity; IEA:Ensembl.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; TAS:ProtInc.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
//
ID   COX14_HUMAN             Reviewed;          57 AA.
AC   Q96I36; B2R5G6;
DE   RecName: Full=Cytochrome c oxidase assembly protein COX14;
GN   Name=COX14; Synonyms=C12orf62;
DR   GO; GO:0033617; P:mitochondrial respiratory chain complex IV assembly; IMP:UniProtKB.
//
ID   COX15_HUMAN             Reviewed;         410 AA.
AC   Q7KZN9; A8K6I9; O60556; O75878; Q5TD00; Q5TD01; Q7Z3Q3; Q9NTN0;
DE   RecName: Full=Cytochrome c oxidase assembly protein COX15 homolog;
GN   Name=COX15;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:UniProtKB.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; IC:HGNC.
DR   GO; GO:0006784; P:heme a biosynthetic process; IGI:HGNC.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IGI:GOC.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IC:HGNC.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; IMP:HGNC.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX16_HUMAN             Reviewed;         106 AA.
AC   Q9P0S2; A6NDT5; A8K3X8;
DE   RecName: Full=Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=COX16; Synonyms=C14orf112; ORFNames=HSPC203, PTD019;
//
ID   COX17_HUMAN             Reviewed;          63 AA.
AC   Q14061; B2R5D2; D3DN84; Q3MHD6;
DE   RecName: Full=Cytochrome c oxidase copper chaperone;
GN   Name=COX17;
DR   GO; GO:0016531; F:copper chaperone activity; IEA:InterPro.
DR   GO; GO:0005507; F:copper ion binding; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006825; P:copper ion transport; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
//
ID   COX18_HUMAN             Reviewed;         333 AA.
AC   Q8N8Q8; Q2PB66; Q2PB67; Q2PB68; Q49B97; Q6IPP9;
DE   RecName: Full=Mitochondrial inner membrane protein COX18;
DE            Short=COX18Hs;
DE   AltName: Full=Cytochrome c oxidase assembly protein 18;
DE   Flags: Precursor;
GN   Name=COX18; Synonyms=OXA1L2;
DR   GO; GO:0008565; F:protein transporter activity; IGI:UniProtKB.
DR   GO; GO:0051204; P:protein insertion into mitochondrial membrane; IGI:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IGI:GOC.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; IGI:UniProtKB.
//
ID   COX19_HUMAN             Reviewed;          90 AA.
AC   Q49B96; A4FTX0;
DE   RecName: Full=Cytochrome c oxidase assembly protein COX19;
DE            Short=hCOX19;
GN   Name=COX19;
//
ID   COX1_HUMAN              Reviewed;         513 AA.
AC   P00395; Q34770;
DE   RecName: Full=Cytochrome c oxidase subunit 1;
DE            EC=1.9.3.1;
DE   AltName: Full=Cytochrome c oxidase polypeptide I;
GN   Name=MT-CO1; Synonyms=COI, COXI, MTCO1;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX20_HUMAN             Reviewed;         118 AA.
AC   Q5RI15; Q8WV86;
DE   RecName: Full=Cytochrome c oxidase protein 20 homolog;
GN   Name=COX20; Synonyms=FAM36A;
//
ID   COX2_HUMAN              Reviewed;         227 AA.
AC   P00403; Q37526;
DE   RecName: Full=Cytochrome c oxidase subunit 2;
DE   AltName: Full=Cytochrome c oxidase polypeptide II;
GN   Name=MT-CO2; Synonyms=COII, COXII, MTCO2;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX3_HUMAN              Reviewed;         261 AA.
AC   P00414; Q14Y83;
DE   RecName: Full=Cytochrome c oxidase subunit 3;
DE   AltName: Full=Cytochrome c oxidase polypeptide III;
GN   Name=MT-CO3; Synonyms=COIII, COXIII, MTCO3;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019646; P:aerobic electron transport chain; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX41_HUMAN             Reviewed;         169 AA.
AC   P13073; B2R4J2; D3DUM7; Q6P666;
DE   RecName: Full=Cytochrome c oxidase subunit 4 isoform 1, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide IV;
DE   AltName: Full=Cytochrome c oxidase subunit IV isoform 1;
DE            Short=COX IV-1;
DE   Flags: Precursor;
GN   Name=COX4I1; Synonyms=COX4;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX42_HUMAN             Reviewed;         171 AA.
AC   Q96KJ9; Q6GTF4; Q9H0Z4;
DE   RecName: Full=Cytochrome c oxidase subunit 4 isoform 2, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase subunit IV isoform 2;
DE            Short=COX IV-2;
DE   Flags: Precursor;
GN   Name=COX4I2; Synonyms=COX4L2;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IDA:UniProtKB.
DR   GO; GO:0045333; P:cellular respiration; NAS:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; NAS:UniProtKB.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IDA:GOC.
DR   GO; GO:0055114; P:oxidation-reduction process; NAS:UniProtKB.
//
ID   COX5A_HUMAN             Reviewed;         150 AA.
AC   P20674; P30045; Q8TB65;
DE   RecName: Full=Cytochrome c oxidase subunit 5A, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide Va;
DE   Flags: Precursor;
GN   Name=COX5A;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX5B_HUMAN             Reviewed;         129 AA.
AC   P10606; Q53YB7; Q96J18; Q99610;
DE   RecName: Full=Cytochrome c oxidase subunit 5B, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide Vb;
DE   Flags: Precursor;
GN   Name=COX5B;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX6C_HUMAN             Reviewed;          75 AA.
AC   P09669; B2R4D7;
DE   RecName: Full=Cytochrome c oxidase subunit 6C;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIc;
GN   Name=COX6C;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX7B_HUMAN             Reviewed;          80 AA.
AC   P24311; B2R4M3; Q6ICR1;
DE   RecName: Full=Cytochrome c oxidase subunit 7B, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIIb;
DE   Flags: Precursor;
GN   Name=COX7B;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; IMP:UniProtKB.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX7C_HUMAN             Reviewed;          63 AA.
AC   P15954; Q6NR81;
DE   RecName: Full=Cytochrome c oxidase subunit 7C, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIIc;
DE   Flags: Precursor;
GN   Name=COX7C;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX7R_HUMAN             Reviewed;         114 AA.
AC   O14548; Q9P118;
DE   RecName: Full=Cytochrome c oxidase subunit 7A-related protein, mitochondrial;
DE   AltName: Full=COX7a-related protein;
DE   AltName: Full=Cytochrome c oxidase subunit VIIa-related protein;
DE   AltName: Full=EB1;
DE   Flags: Precursor;
GN   Name=COX7A2L; Synonyms=COX7AR, COX7RP;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX7S_HUMAN             Reviewed;         106 AA.
AC   O60397;
DE   RecName: Full=Putative cytochrome c oxidase subunit 7A3, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase subunit VIIa 3;
DE   Flags: Precursor;
GN   Name=COX7A2P2; Synonyms=COX7A3, COX7AL2, COX7AP2;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
//
ID   COX8A_HUMAN             Reviewed;          69 AA.
AC   P10176; P15955;
DE   RecName: Full=Cytochrome c oxidase subunit 8A, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIII-liver/heart;
DE   AltName: Full=Cytochrome c oxidase subunit 8-2;
DE   Flags: Precursor;
GN   Name=COX8A; Synonyms=COX8, COX8L;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   COX8C_HUMAN             Reviewed;          72 AA.
AC   Q7Z4L0; Q495K7;
DE   RecName: Full=Cytochrome c oxidase subunit 8C, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide 8 isoform 3;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIII isoform 3;
DE            Short=COX VIII-3;
DE   AltName: Full=Cytochrome c oxidase subunit 8-3;
DE   Flags: Precursor;
GN   Name=COX8C;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
//
ID   COXM1_HUMAN             Reviewed;         106 AA.
AC   Q7Z7K0; Q68DJ7;
DE   RecName: Full=COX assembly mitochondrial protein homolog;
DE            Short=Cmc1p;
GN   Name=CMC1; Synonyms=C3orf68;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   COXM2_HUMAN             Reviewed;          79 AA.
AC   Q9NRP2; D3DUK6;
DE   RecName: Full=COX assembly mitochondrial protein 2 homolog;
GN   Name=CMC2; Synonyms=C16orf61; ORFNames=DC13;
//
ID   CP003_HUMAN             Reviewed;         125 AA.
AC   O95177; O95176; Q52LX9;
DE   RecName: Full=Uncharacterized protein C16orf3;
GN   Name=C16orf3;
//
ID   CP013_HUMAN             Reviewed;         204 AA.
AC   Q96S19; A8MTR1; A8MWJ8; A8MZA1; B4DG95; B4DIJ3; D6REA6; F6TF62;
AC   F6VM53; Q96IW1; Q96MD6;
DE   RecName: Full=UPF0585 protein C16orf13;
GN   Name=C16orf13; ORFNames=JFP2;
//
ID   CP045_HUMAN             Reviewed;         204 AA.
AC   Q96MC5; O00223; O75769; Q8IZ36; Q96H25;
DE   RecName: Full=Uncharacterized protein C16orf45;
GN   Name=C16orf45;
//
ID   CP046_HUMAN             Reviewed;         395 AA.
AC   Q6P387; Q96MA7;
DE   RecName: Full=Uncharacterized protein C16orf46;
GN   Name=C16orf46;
//
ID   CP047_HUMAN             Reviewed;         133 AA.
AC   Q6ZP98;
DE   RecName: Full=Putative uncharacterized protein C16orf47;
GN   Name=C16orf47;
//
ID   CP054_HUMAN             Reviewed;         224 AA.
AC   Q6UWD8; A6NJR6; Q8NAB0;
DE   RecName: Full=Transmembrane protein C16orf54;
GN   Name=C16orf54; ORFNames=UNQ9389/PRO34280;
//
ID   CP052_HUMAN             Reviewed;         167 AA.
AC   Q8NHV5; H3BNM6;
DE   RecName: Full=Uncharacterized protein C16orf52;
GN   Name=C16orf52;
//
ID   CP058_HUMAN             Reviewed;         468 AA.
AC   Q96GQ5; Q53GL8; Q8NAJ4; Q9BVY3; Q9H887;
DE   RecName: Full=UPF0420 protein C16orf58;
GN   Name=C16orf58;
//
ID   CP059_HUMAN             Reviewed;         433 AA.
AC   Q7L2K0; B4DXD7; Q96H61; Q9H872;
DE   RecName: Full=Uncharacterized protein C16orf59;
GN   Name=C16orf59;
//
ID   CP062_HUMAN             Reviewed;         963 AA.
AC   Q7Z3J2; A8K2M1; O43329; Q69YI1; Q6PDA0; Q7L371; Q86W66; Q8WXA5;
AC   Q9H0L7; Q9H7C8;
DE   RecName: Full=UPF0505 protein C16orf62;
DE   AltName: Full=Esophageal cancer-associated protein;
GN   Name=C16orf62; ORFNames=101F10.2;
//
ID   CP070_HUMAN             Reviewed;         422 AA.
AC   Q9BSU1; Q9HA86;
DE   RecName: Full=UPF0183 protein C16orf70;
GN   Name=C16orf70; Synonyms=C16orf6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CP071_HUMAN             Reviewed;         520 AA.
AC   Q8IYS4; Q8NCV0;
DE   RecName: Full=Uncharacterized protein C16orf71;
GN   Name=C16orf71;
//
ID   CP074_HUMAN             Reviewed;          76 AA.
AC   Q96GX8;
DE   RecName: Full=Uncharacterized protein C16orf74;
GN   Name=C16orf74;
//
ID   CP072_HUMAN             Reviewed;         275 AA.
AC   Q14CZ0;
DE   RecName: Full=UPF0472 protein C16orf72;
GN   Name=C16orf72;
//
ID   CP078_HUMAN             Reviewed;         265 AA.
AC   Q8WTQ4;
DE   RecName: Full=Uncharacterized protein C16orf78;
GN   Name=C16orf78;
//
ID   CP080_HUMAN             Reviewed;         193 AA.
AC   Q9Y6A4;
DE   RecName: Full=UPF0468 protein C16orf80;
DE   AltName: Full=Transcription factor IIB;
GN   Name=C16orf80;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   CP086_HUMAN             Reviewed;         317 AA.
AC   Q6ZW13; B5MCW6;
DE   RecName: Full=Uncharacterized protein C16orf86;
GN   Name=C16orf86;
//
ID   CP087_HUMAN             Reviewed;         154 AA.
AC   Q6PH81; Q63HN9;
DE   RecName: Full=UPF0547 protein C16orf87;
GN   Name=C16orf87;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CP081_HUMAN             Reviewed;         145 AA.
AC   Q8N9R0;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00304;
GN   Name=LINC00304; Synonyms=C16orf81, NCRNA00304;
//
ID   CP089_HUMAN             Reviewed;         402 AA.
AC   Q6UX73; B4DUM5; Q8N2I3; Q8N4T1;
DE   RecName: Full=UPF0764 protein C16orf89;
DE   Flags: Precursor;
GN   Name=C16orf89; ORFNames=UNQ904/PRO1925;
//
ID   CP090_HUMAN             Reviewed;         172 AA.
AC   A8MZG2;
DE   RecName: Full=Uncharacterized protein C16orf90;
GN   Name=C16orf90;
//
ID   CP093_HUMAN             Reviewed;         331 AA.
AC   A1A4V9; A1A4V8; F5GX13; Q569G2;
DE   RecName: Full=Coiled-coil domain-containing protein C16orf93;
GN   Name=C16orf93;
//
ID   CP092_HUMAN             Reviewed;         132 AA.
AC   Q96LL3; Q494R8;
DE   RecName: Full=Uncharacterized protein C16orf92;
GN   Name=C16orf92;
//
ID   CP095_HUMAN             Reviewed;         158 AA.
AC   Q9H693;
DE   RecName: Full=Uncharacterized protein C16orf95;
GN   Name=C16orf95;
//
ID   CP096_HUMAN             Reviewed;        1141 AA.
AC   A6NNT2; C9JH24;
DE   RecName: Full=Putative uncharacterized protein C16orf96;
GN   Name=C16orf96;
//
ID   CP097_HUMAN             Reviewed;         126 AA.
AC   H3BN30;
DE   RecName: Full=Uncharacterized protein C16orf97;
GN   Name=C16orf97;
//
ID   CP098_HUMAN             Reviewed;         204 AA.
AC   I3L0S3;
DE   RecName: Full=Putative uncharacterized protein C16Orf98;
GN   Name=C16orf98;
//
ID   CP110_HUMAN             Reviewed;        1012 AA.
AC   O43303; B7WP23; O43335; Q68DV9; Q8NE13;
DE   RecName: Full=Centriolar coiled-coil protein of 110 kDa;
DE   AltName: Full=Centrosomal protein of 110 kDa;
DE            Short=CP110;
DE            Short=Cep110;
GN   Name=CCP110; Synonyms=CEP110, CP110, KIAA0419;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0007099; P:centriole replication; IMP:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
//
ID   CP11A_HUMAN             Reviewed;         521 AA.
AC   P05108; A8K8D5; B3KPU8; G3XAD7; Q15081; Q16805; Q8N1A7;
DE   RecName: Full=Cholesterol side-chain cleavage enzyme, mitochondrial;
DE            EC=1.14.15.6;
DE   AltName: Full=CYPXIA1;
DE   AltName: Full=Cholesterol desmolase;
DE   AltName: Full=Cytochrome P450 11A1;
DE   AltName: Full=Cytochrome P450(scc);
DE   Flags: Precursor;
GN   Name=CYP11A1; Synonyms=CYP11A;
DR   GuidetoPHARMACOLOGY; 1358; -.
DR   GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR   GO; GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0018879; P:biphenyl metabolic process; IEA:Ensembl.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:UniProtKB.
DR   GO; GO:0018894; P:dibenzo-p-dioxin metabolic process; IEA:Ensembl.
DR   GO; GO:0006703; P:estrogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050756; P:fractalkine metabolic process; IEA:Ensembl.
DR   GO; GO:0060014; P:granulosa cell differentiation; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0007617; P:mating behavior; IEA:Ensembl.
DR   GO; GO:0018958; P:phenol-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:0018963; P:phthalate metabolic process; IEA:Ensembl.
DR   GO; GO:0006701; P:progesterone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043279; P:response to alkaloid; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0060992; P:response to fungicide; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0033595; P:response to genistein; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0017085; P:response to insecticide; IEA:Ensembl.
DR   GO; GO:0033591; P:response to L-ascorbic acid; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0014037; P:Schwann cell differentiation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0061370; P:testosterone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042359; P:vitamin D metabolic process; ISS:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP131_HUMAN             Reviewed;        1083 AA.
AC   Q9UPN4; A6NHI8; B2RN11; Q96F50;
DE   RecName: Full=Centrosomal protein of 131 kDa;
DE   AltName: Full=5-azacytidine-induced protein 1;
DE   AltName: Full=Pre-acrosome localization protein 1;
GN   Name=CEP131; Synonyms=AZI1, KIAA1118;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035735; P:intraciliary transport involved in cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CP135_HUMAN             Reviewed;        1140 AA.
AC   Q66GS9; B2RMY0; O75130; Q58F25; Q9H8H7;
DE   RecName: Full=Centrosomal protein of 135 kDa;
DE            Short=Cep135;
DE   AltName: Full=Centrosomal protein 4;
GN   Name=CEP135; Synonyms=CEP4, KIAA0635;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007099; P:centriole replication; IMP:UniProtKB.
DR   GO; GO:0010457; P:centriole-centriole cohesion; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   CP17A_HUMAN             Reviewed;         508 AA.
AC   P05093; Q5TZV7;
DE   RecName: Full=Steroid 17-alpha-hydroxylase/17,20 lyase;
DE            EC=1.14.99.9;
DE            EC=4.1.2.30;
DE   AltName: Full=17-alpha-hydroxyprogesterone aldolase;
DE   AltName: Full=CYPXVII;
DE   AltName: Full=Cytochrome P450 17A1;
DE   AltName: Full=Cytochrome P450-C17;
DE            Short=Cytochrome P450c17;
DE   AltName: Full=Steroid 17-alpha-monooxygenase;
GN   Name=CYP17A1; Synonyms=CYP17, S17AH;
DR   GuidetoPHARMACOLOGY; 1361; -.
DR   GO; GO:0047442; F:17-alpha-hydroxyprogesterone aldolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0004508; F:steroid 17-alpha-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:Reactome.
DR   GO; GO:0018879; P:biphenyl metabolic process; IEA:Ensembl.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0018894; P:dibenzo-p-dioxin metabolic process; IEA:Ensembl.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0042446; P:hormone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0030728; P:ovulation; IEA:Ensembl.
DR   GO; GO:0018958; P:phenol-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:0018963; P:phthalate metabolic process; IEA:Ensembl.
DR   GO; GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.
DR   GO; GO:0010034; P:response to acetate; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0060992; P:response to fungicide; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0017085; P:response to insecticide; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0007548; P:sex differentiation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0008202; P:steroid metabolic process; IDA:UniProtKB.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP19A_HUMAN             Reviewed;         503 AA.
AC   P11511; Q16731; Q3B764; Q58FA0;
DE   RecName: Full=Aromatase;
DE            EC=1.14.14.14;
DE   AltName: Full=CYPXIX;
DE   AltName: Full=Cytochrome P-450AROM;
DE   AltName: Full=Cytochrome P450 19A1;
DE   AltName: Full=Estrogen synthase;
GN   Name=CYP19A1; Synonyms=ARO1, CYAR, CYP19;
DR   GuidetoPHARMACOLOGY; 1362; -.
DR   GO; GO:0070330; F:aromatase activity; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0060736; P:prostate gland growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP1A1_HUMAN             Reviewed;         512 AA.
AC   P04798; A4F3V9; A4F3W0; Q53G18;
DE   RecName: Full=Cytochrome P450 1A1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIA1;
DE   AltName: Full=Cytochrome P450 form 6;
DE   AltName: Full=Cytochrome P450-C;
DE   AltName: Full=Cytochrome P450-P1;
GN   Name=CYP1A1;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032451; F:demethylase activity; IEA:Ensembl.
DR   GO; GO:0016711; F:flavonoid 3'-monooxygenase activity; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0016679; F:oxidoreductase activity, acting on diphenols and related substances as donors; IEA:Ensembl.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0008395; F:steroid hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0042904; P:9-cis-retinoic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0009308; P:amine metabolic process; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.
DR   GO; GO:0009804; P:coumarin metabolic process; IEA:Ensembl.
DR   GO; GO:0019341; P:dibenzo-p-dioxin catabolic process; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:Ensembl.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0009812; P:flavonoid metabolic process; IEA:Ensembl.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0017143; P:insecticide metabolic process; IEA:Ensembl.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010041; P:response to iron(III) ion; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009624; P:response to nematode; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP1A2_HUMAN             Reviewed;         515 AA.
AC   P05177; Q16754; Q6NWU5; Q9BXX7; Q9UK49;
DE   RecName: Full=Cytochrome P450 1A2;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIA2;
DE   AltName: Full=Cytochrome P(3)450;
DE   AltName: Full=Cytochrome P450 4;
DE   AltName: Full=Cytochrome P450-P3;
GN   Name=CYP1A2;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.
DR   GO; GO:0032451; F:demethylase activity; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IMP:UniProtKB.
DR   GO; GO:0009820; P:alkaloid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0045333; P:cellular respiration; IEA:Ensembl.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0018894; P:dibenzo-p-dioxin metabolic process; IEA:Ensembl.
DR   GO; GO:0042737; P:drug catabolic process; IMP:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0032787; P:monocarboxylic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0071615; P:oxidative deethylation; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.
DR   GO; GO:0009403; P:toxin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP1B1_HUMAN             Reviewed;         543 AA.
AC   Q16678; Q5TZW8; Q93089; Q9H316;
DE   RecName: Full=Cytochrome P450 1B1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIB1;
GN   Name=CYP1B1;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; TAS:UniProtKB.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IDA:MGI.
DR   GO; GO:0019825; F:oxygen binding; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.
DR   GO; GO:0043542; P:endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0071603; P:endothelial cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IDA:UniProtKB.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0009404; P:toxin metabolic process; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   CP20A_HUMAN             Reviewed;         462 AA.
AC   Q6UW02; Q4ZG61; Q8N4Q8; Q8WWA9;
DE   RecName: Full=Cytochrome P450 20A1;
DE            EC=1.14.-.-;
GN   Name=CYP20A1; ORFNames=UNQ667/PRO1301;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
//
ID   CP21A_HUMAN             Reviewed;         494 AA.
AC   P08686; A2BHY6; P04033; Q01204; Q08AG8; Q16749; Q16806; Q5ST44;
AC   Q96NU8;
DE   RecName: Full=Steroid 21-hydroxylase;
DE            EC=1.14.99.10;
DE   AltName: Full=21-OHase;
DE   AltName: Full=Cytochrome P-450c21;
DE   AltName: Full=Cytochrome P450 21;
DE   AltName: Full=Cytochrome P450 XXI;
DE   AltName: Full=Cytochrome P450-C21;
DE   AltName: Full=Cytochrome P450-C21B;
GN   Name=CYP21A2; Synonyms=CYP21, CYP21B;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004509; F:steroid 21-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008395; F:steroid hydroxylase activity; TAS:ProtInc.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006705; P:mineralocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP24A_HUMAN             Reviewed;         514 AA.
AC   Q07973; Q15807; Q32ML3; Q5I2W7;
DE   RecName: Full=1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial;
DE            Short=24-OHase;
DE            Short=Vitamin D(3) 24-hydroxylase;
DE            EC=1.14.13.126;
DE   AltName: Full=Cytochrome P450 24A1;
DE   AltName: Full=Cytochrome P450-CC24;
DE   Flags: Precursor;
GN   Name=CYP24A1; Synonyms=CYP24;
DR   GO; GO:0030342; F:1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0008403; F:25-hydroxycholecalciferol-24-hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; TAS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0033280; P:response to vitamin D; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0042369; P:vitamin D catabolic process; NAS:BHF-UCL.
DR   GO; GO:0042359; P:vitamin D metabolic process; TAS:Reactome.
DR   GO; GO:0070561; P:vitamin D receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP250_HUMAN             Reviewed;        2442 AA.
AC   Q9BV73; E1P5Q3; O14812; O60588; Q9H450;
DE   RecName: Full=Centrosome-associated protein CEP250;
DE   AltName: Full=250 kDa centrosomal protein;
DE            Short=Cep250;
DE   AltName: Full=Centrosomal Nek2-associated protein 1;
DE            Short=C-Nap1;
DE   AltName: Full=Centrosomal protein 2;
GN   Name=CEP250; Synonyms=CEP2, CNAP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0010457; P:centriole-centriole cohesion; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:0030997; P:regulation of centriole-centriole cohesion; IDA:UniProtKB.
//
ID   CP26A_HUMAN             Reviewed;         497 AA.
AC   O43174; B3KNI4; Q5VXH9; Q5VXI0;
DE   RecName: Full=Cytochrome P450 26A1;
DE            EC=1.14.-.-;
DE   AltName: Full=Cytochrome P450 retinoic acid-inactivating 1;
DE            Short=Cytochrome P450RAI;
DE            Short=hP450RAI;
DE   AltName: Full=Retinoic acid 4-hydroxylase;
DE   AltName: Full=Retinoic acid-metabolizing cytochrome;
GN   Name=CYP26A1; Synonyms=CYP26, P450RAI1;
DR   GO; GO:0020037; F:heme binding; NAS:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP26B_HUMAN             Reviewed;         512 AA.
AC   Q9NR63; B2R8M7; B7Z2K6; B7Z2P4; B7Z3B8; E4W5W7; Q32MC0; Q53TW1;
AC   Q9NP41;
DE   RecName: Full=Cytochrome P450 26B1;
DE            EC=1.14.-.-;
DE   AltName: Full=Cytochrome P450 26A2;
DE   AltName: Full=Cytochrome P450 retinoic acid-inactivating 2;
DE            Short=Cytochrome P450RAI-2;
DE   AltName: Full=Retinoic acid-metabolizing cytochrome;
GN   Name=CYP26B1; Synonyms=CYP26A2, P450RAI2;
DR   GO; GO:0020037; F:heme binding; NAS:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0060349; P:bone morphogenesis; IMP:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; ISS:BHF-UCL.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007140; P:male meiosis; ISS:BHF-UCL.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:2001037; P:positive regulation of tongue muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; ISS:BHF-UCL.
DR   GO; GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; ISS:BHF-UCL.
DR   GO; GO:0043587; P:tongue morphogenesis; IEA:Ensembl.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP26C_HUMAN             Reviewed;         522 AA.
AC   Q6V0L0; Q5VXH6;
DE   RecName: Full=Cytochrome P450 26C1;
DE            EC=1.14.-.-;
GN   Name=CYP26C1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.
DR   GO; GO:0007417; P:central nervous system development; ISS:BHF-UCL.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0014032; P:neural crest cell development; ISS:BHF-UCL.
DR   GO; GO:0048284; P:organelle fusion; ISS:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP27A_HUMAN             Reviewed;         531 AA.
AC   Q02318; A8K303; Q6LDB4; Q86YQ6;
DE   RecName: Full=Sterol 26-hydroxylase, mitochondrial;
DE            EC=1.14.13.15;
DE   AltName: Full=5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase;
DE   AltName: Full=Cytochrome P-450C27/25;
DE   AltName: Full=Cytochrome P450 27;
DE   AltName: Full=Sterol 27-hydroxylase;
DE   AltName: Full=Vitamin D(3) 25-hydroxylase;
DE   Flags: Precursor;
GN   Name=CYP27A1; Synonyms=CYP27;
DR   GO; GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031073; F:cholesterol 26-hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008395; F:steroid hydroxylase activity; TAS:ProtInc.
DR   GO; GO:0030343; F:vitamin D3 25-hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP27B_HUMAN             Reviewed;         508 AA.
AC   O15528; B2RC61; Q548T3;
DE   RecName: Full=25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;
DE            EC=1.14.13.13;
DE   AltName: Full=25-OHD-1 alpha-hydroxylase;
DE   AltName: Full=25-hydroxyvitamin D(3) 1-alpha-hydroxylase;
DE            Short=VD3 1A hydroxylase;
DE   AltName: Full=Calcidiol 1-monooxygenase;
DE   AltName: Full=Cytochrome P450 subfamily XXVIIB polypeptide 1;
DE   AltName: Full=Cytochrome P450C1 alpha;
DE   AltName: Full=Cytochrome P450VD1-alpha;
DE   AltName: Full=Cytochrome p450 27B1;
DE   Flags: Precursor;
GN   Name=CYP27B1; Synonyms=CYP1ALPHA, CYP27B;
DR   GO; GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0030282; P:bone mineralization; IEP:BHF-UCL.
DR   GO; GO:0036378; P:calcitriol biosynthetic process from calciol; IDA:BHF-UCL.
DR   GO; GO:0055074; P:calcium ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; ISS:BHF-UCL.
DR   GO; GO:0046697; P:decidualization; IEP:BHF-UCL.
DR   GO; GO:0070314; P:G1 to G0 transition; IMP:BHF-UCL.
DR   GO; GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0070564; P:positive regulation of vitamin D receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030500; P:regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEP:BHF-UCL.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0033280; P:response to vitamin D; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0042369; P:vitamin D catabolic process; IEA:Ensembl.
DR   GO; GO:0042359; P:vitamin D metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2A6_HUMAN             Reviewed;         494 AA.
AC   P11509; A7YAE5; B2R7F6; P00190; P10890; Q16803; Q4VAT9; Q4VAU0;
AC   Q4VAU1; Q9H1Z7; Q9UCU0; Q9UK48;
DE   RecName: Full=Cytochrome P450 2A6;
DE            EC=1.14.13.-;
DE   AltName: Full=1,4-cineole 2-exo-monooxygenase;
DE   AltName: Full=CYPIIA6;
DE   AltName: Full=Coumarin 7-hydroxylase;
DE   AltName: Full=Cytochrome P450 IIA3;
DE   AltName: Full=Cytochrome P450(I);
GN   Name=CYP2A6; Synonyms=CYP2A3;
DR   GO; GO:0008389; F:coumarin 7-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   GO; GO:0046226; P:coumarin catabolic process; IDA:BHF-UCL.
DR   GO; GO:0009804; P:coumarin metabolic process; IDA:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2A7_HUMAN             Reviewed;         494 AA.
AC   P20853; Q13121;
DE   RecName: Full=Cytochrome P450 2A7;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIA7;
DE   AltName: Full=Cytochrome P450 IIA4;
GN   Name=CYP2A7;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
//
ID   CP2AD_HUMAN             Reviewed;         494 AA.
AC   Q16696; Q53YR8; Q6R569; Q6R570; Q9H2X2;
DE   RecName: Full=Cytochrome P450 2A13;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIA13;
GN   Name=CYP2A13;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2B6_HUMAN             Reviewed;         491 AA.
AC   P20813; Q2V565; Q9UK46;
DE   RecName: Full=Cytochrome P450 2B6;
DE            EC=1.14.13.-;
DE   AltName: Full=1,4-cineole 2-exo-monooxygenase;
DE   AltName: Full=CYPIIB6;
DE   AltName: Full=Cytochrome P450 IIB1;
GN   Name=CYP2B6;
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   GO; GO:0042180; P:cellular ketone metabolic process; IDA:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   CP2C8_HUMAN             Reviewed;         490 AA.
AC   P10632; A8K9N8; B0AZN2; B7Z1F6; Q5VX93; Q8WWB1; Q9UCZ9;
DE   RecName: Full=Cytochrome P450 2C8;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIC8;
DE   AltName: Full=Cytochrome P450 IIC2;
DE   AltName: Full=Cytochrome P450 MP-12;
DE   AltName: Full=Cytochrome P450 MP-20;
DE   AltName: Full=Cytochrome P450 form 1;
DE   AltName: Full=S-mephenytoin 4-hydroxylase;
GN   Name=CYP2C8;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0006082; P:organic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2C9_HUMAN             Reviewed;         490 AA.
AC   P11712; P11713; Q16756; Q16872; Q5VX92;
DE   RecName: Full=Cytochrome P450 2C9;
DE            EC=1.14.13.-;
DE   AltName: Full=(R)-limonene 6-monooxygenase;
DE            EC=1.14.13.80;
DE   AltName: Full=(S)-limonene 6-monooxygenase;
DE            EC=1.14.13.48;
DE   AltName: Full=(S)-limonene 7-monooxygenase;
DE            EC=1.14.13.49;
DE   AltName: Full=CYPIIC9;
DE   AltName: Full=Cytochrome P-450MP;
DE   AltName: Full=Cytochrome P450 MP-4;
DE   AltName: Full=Cytochrome P450 MP-8;
DE   AltName: Full=Cytochrome P450 PB-1;
DE   AltName: Full=S-mephenytoin 4-hydroxylase;
GN   Name=CYP2C9; Synonyms=CYP2C10;
DR   GO; GO:0052741; F:(R)-limonene 6-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018675; F:(S)-limonene 6-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018676; F:(S)-limonene 7-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; NAS:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0008395; F:steroid hydroxylase activity; IMP:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0043603; P:cellular amide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042737; P:drug catabolic process; IMP:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IMP:UniProtKB.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0032787; P:monocarboxylic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0019627; P:urea metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2CI_HUMAN             Reviewed;         490 AA.
AC   P33260; B2R8K2; Q16703; Q16751; Q4VAT5; Q6GRG1;
DE   RecName: Full=Cytochrome P450 2C18;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIC18;
DE   AltName: Full=Cytochrome P450-6b/29c;
GN   Name=CYP2C18;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; TAS:ProtInc.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2CJ_HUMAN             Reviewed;         490 AA.
AC   P33261; P33259; Q8WZB1; Q8WZB2; Q9UCD4;
DE   RecName: Full=Cytochrome P450 2C19;
DE            EC=1.14.13.-;
DE   AltName: Full=(R)-limonene 6-monooxygenase;
DE            EC=1.14.13.80;
DE   AltName: Full=(S)-limonene 6-monooxygenase;
DE            EC=1.14.13.48;
DE   AltName: Full=(S)-limonene 7-monooxygenase;
DE            EC=1.14.13.49;
DE   AltName: Full=CYPIIC17;
DE   AltName: Full=CYPIIC19;
DE   AltName: Full=Cytochrome P450-11A;
DE   AltName: Full=Cytochrome P450-254C;
DE   AltName: Full=Mephenytoin 4-hydroxylase;
GN   Name=CYP2C19;
DR   GO; GO:0052741; F:(R)-limonene 6-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018675; F:(S)-limonene 6-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018676; F:(S)-limonene 7-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0008395; F:steroid hydroxylase activity; IMP:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.
DR   GO; GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2D6_HUMAN             Reviewed;         497 AA.
AC   P10635; Q16752; Q2XND6; Q2XND7; Q2XNE0; Q6B012; Q6NXU8;
DE   RecName: Full=Cytochrome P450 2D6;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIID6;
DE   AltName: Full=Cytochrome P450-DB1;
DE   AltName: Full=Debrisoquine 4-hydroxylase;
GN   Name=CYP2D6; Synonyms=CYP2DL1;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0009820; P:alkaloid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0009804; P:coumarin metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042737; P:drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.
DR   GO; GO:0033076; P:isoquinoline alkaloid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051100; P:negative regulation of binding; IDA:BHF-UCL.
DR   GO; GO:0090350; P:negative regulation of cellular organofluorine metabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL.
//
ID   CP2E1_HUMAN             Reviewed;         493 AA.
AC   P05181; Q5VZD5; Q6NWT9; Q9UK47;
DE   RecName: Full=Cytochrome P450 2E1;
DE            EC=1.14.13.-;
DE   AltName: Full=4-nitrophenol 2-hydroxylase;
DE            EC=1.14.13.n7;
DE   AltName: Full=CYPIIE1;
DE   AltName: Full=Cytochrome P450-J;
DE   Contains:
DE     RecName: Full=Cytochrome P450 2E1, N-terminally processed;
GN   Name=CYP2E1; Synonyms=CYP2E;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; TAS:UniProtKB.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:Ensembl.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.
DR   GO; GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0010193; P:response to ozone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2F1_HUMAN             Reviewed;         491 AA.
AC   P24903; A7KAU6; A7KAU7; A7KAU8; A7KAU9; A7KAV0; Q8WWJ2;
DE   RecName: Full=Cytochrome P450 2F1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIF1;
GN   Name=CYP2F1;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; TAS:ProtInc.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IDA:UniProtKB.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0018931; P:naphthalene metabolic process; IDA:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0018979; P:trichloroethylene metabolic process; IEA:Ensembl.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2J2_HUMAN             Reviewed;         502 AA.
AC   P51589; B2RD33; Q8TF13;
DE   RecName: Full=Cytochrome P450 2J2;
DE            EC=1.14.14.1;
DE   AltName: Full=Arachidonic acid epoxygenase;
DE   AltName: Full=CYPIIJ2;
GN   Name=CYP2J2;
DR   GO; GO:0008405; F:arachidonic acid 11,12-epoxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0008404; F:arachidonic acid 14,15-epoxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0008392; F:arachidonic acid epoxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0071614; F:linoleic acid epoxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; IDA:BHF-UCL.
DR   GO; GO:0006690; P:icosanoid metabolic process; TAS:ProtInc.
DR   GO; GO:0043651; P:linoleic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:BHF-UCL.
//
ID   CP2R1_HUMAN             Reviewed;         501 AA.
AC   Q6VVX0; Q2M3H3; Q5RT65;
DE   RecName: Full=Vitamin D 25-hydroxylase;
DE            EC=1.14.13.159;
DE   AltName: Full=Cytochrome P450 2R1;
GN   Name=CYP2R1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0030343; F:vitamin D3 25-hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0010164; P:response to cesium ion; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0042359; P:vitamin D metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2S1_HUMAN             Reviewed;         504 AA.
AC   Q96SQ9; Q9BZ66;
DE   RecName: Full=Cytochrome P450 2S1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIS1;
GN   Name=CYP2S1; ORFNames=UNQ891/PRO1906;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2U1_HUMAN             Reviewed;         544 AA.
AC   Q7Z449; B2RMV7; Q96EQ6;
DE   RecName: Full=Cytochrome P450 2U1;
DE            EC=1.14.14.1;
GN   Name=CYP2U1;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP2W1_HUMAN             Reviewed;         490 AA.
AC   Q8TAV3;
DE   RecName: Full=Cytochrome P450 2W1;
DE            EC=1.14.14.-;
DE   AltName: Full=CYPIIW1;
GN   Name=CYP2W1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP343_HUMAN             Reviewed;         503 AA.
AC   Q9HB55; Q75MK2; Q9HB52; Q9HB53; Q9HB54; Q9HB57;
DE   RecName: Full=Cytochrome P450 3A43;
DE            EC=1.14.14.1;
GN   Name=CYP3A43;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP39A_HUMAN             Reviewed;         469 AA.
AC   Q9NYL5; Q5VTT0; Q96FW5;
DE   RecName: Full=24-hydroxycholesterol 7-alpha-hydroxylase;
DE            EC=1.14.13.99;
DE   AltName: Full=Cytochrome P450 39A1;
DE            Short=hCYP39A1;
DE   AltName: Full=Oxysterol 7-alpha-hydroxylase;
GN   Name=CYP39A1;
DR   GO; GO:0033782; F:24-hydroxycholesterol 7alpha-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0008387; F:steroid 7-alpha-hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0006707; P:cholesterol catabolic process; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP3A4_HUMAN             Reviewed;         503 AA.
AC   P08684; P05184; Q16757; Q9UK50;
DE   RecName: Full=Cytochrome P450 3A4;
DE            EC=1.14.13.-;
DE   AltName: Full=1,8-cineole 2-exo-monooxygenase;
DE            EC=1.14.13.157;
DE   AltName: Full=Albendazole monooxygenase;
DE            EC=1.14.13.32;
DE   AltName: Full=Albendazole sulfoxidase;
DE   AltName: Full=CYPIIIA3;
DE   AltName: Full=CYPIIIA4;
DE   AltName: Full=Cytochrome P450 3A3;
DE   AltName: Full=Cytochrome P450 HLp;
DE   AltName: Full=Cytochrome P450 NF-25;
DE   AltName: Full=Cytochrome P450-PCN1;
DE   AltName: Full=Nifedipine oxidase;
DE   AltName: Full=Quinine 3-monooxygenase;
DE            EC=1.14.13.67;
DE   AltName: Full=Taurochenodeoxycholate 6-alpha-hydroxylase;
DE            EC=1.14.13.97;
GN   Name=CYP3A4; Synonyms=CYP3A3;
DR   GuidetoPHARMACOLOGY; 1337; -.
DR   GO; GO:0047638; F:albendazole monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IDA:BHF-UCL.
DR   GO; GO:0004497; F:monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0050591; F:quinine 3-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005496; F:steroid binding; IDA:BHF-UCL.
DR   GO; GO:0008395; F:steroid hydroxylase activity; IMP:BHF-UCL.
DR   GO; GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:BHF-UCL.
DR   GO; GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0008209; P:androgen metabolic process; TAS:BHF-UCL.
DR   GO; GO:0036378; P:calcitriol biosynthetic process from calciol; IDA:GOC.
DR   GO; GO:0042737; P:drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.
DR   GO; GO:0008202; P:steroid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP3A5_HUMAN             Reviewed;         502 AA.
AC   P20815; A4D289; B7Z5I7; Q53WY8; Q75MV0; Q9HB56;
DE   RecName: Full=Cytochrome P450 3A5;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIIA5;
DE   AltName: Full=Cytochrome P450 HLp2;
DE   AltName: Full=Cytochrome P450-PCN3;
GN   Name=CYP3A5;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0042737; P:drug catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP3A7_HUMAN             Reviewed;         503 AA.
AC   P24462; A4D288;
DE   RecName: Full=Cytochrome P450 3A7;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIIIA7;
DE   AltName: Full=Cytochrome P450-HFLA;
GN   Name=CYP3A7;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP46A_HUMAN             Reviewed;         500 AA.
AC   Q9Y6A2; B4DHP8; E7EQG9; Q8N2B0;
DE   RecName: Full=Cholesterol 24-hydroxylase;
DE            Short=CH24H;
DE            EC=1.14.13.98;
DE   AltName: Full=Cytochrome P450 46A1;
GN   Name=CYP46A1; Synonyms=CYP46;
DR   GO; GO:0033781; F:cholesterol 24-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008395; F:steroid hydroxylase activity; TAS:ProtInc.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0006707; P:cholesterol catabolic process; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   CP4AB_HUMAN             Reviewed;         519 AA.
AC   Q02928; Q06766; Q16865; Q16866; Q5VSP8; Q86SU6; Q8IWY5;
DE   RecName: Full=Cytochrome P450 4A11;
DE   AltName: Full=20-hydroxyeicosatetraenoic acid synthase;
DE            Short=20-HETE synthase;
DE   AltName: Full=CYP4AII;
DE   AltName: Full=CYPIVA11;
DE   AltName: Full=Cytochrome P-450HK-omega;
DE   AltName: Full=Cytochrome P450HL-omega;
DE   AltName: Full=Fatty acid omega-hydroxylase;
DE   AltName: Full=Lauric acid omega-hydroxylase;
DE            EC=1.14.15.3;
DE   Flags: Precursor;
GN   Name=CYP4A11; Synonyms=CYP4A2;
DR   GO; GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; TAS:ProtInc.
DR   GO; GO:0036101; P:leukotriene B4 catabolic process; IDA:GOC.
DR   GO; GO:0006691; P:leukotriene metabolic process; IDA:UniProtKB.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.
DR   GO; GO:0003095; P:pressure natriuresis; IEP:UniProtKB.
DR   GO; GO:0003091; P:renal water homeostasis; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4AM_HUMAN             Reviewed;         519 AA.
AC   Q5TCH4; Q5TCH3; Q6JXK7; Q6JXK8; Q9NRM4;
DE   RecName: Full=Cytochrome P450 4A22;
DE   AltName: Full=CYPIVA22;
DE   AltName: Full=Fatty acid omega-hydroxylase;
DE   AltName: Full=Lauric acid omega-hydroxylase;
DE            EC=1.14.15.3;
DE   Flags: Precursor;
GN   Name=CYP4A22;
DR   GO; GO:0018685; F:alkane 1-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
//
ID   CP4B1_HUMAN             Reviewed;         511 AA.
AC   P13584; Q1HBI2; Q8TD85; Q8WWF2; Q8WWU9; Q8WWV0;
DE   RecName: Full=Cytochrome P450 4B1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIVB1;
DE   AltName: Full=Cytochrome P450-HP;
GN   Name=CYP4B1;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0018585; F:fluorene oxygenase activity; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0018879; P:biphenyl metabolic process; IEA:Ensembl.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IEA:Ensembl.
DR   GO; GO:0018917; P:fluorene metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4F2_HUMAN             Reviewed;         520 AA.
AC   P78329; A8K425; Q16677; Q6NWT4; Q6NWT6; Q9NNZ0; Q9UIU8;
DE   RecName: Full=Leukotriene-B(4) omega-hydroxylase 1;
DE            EC=1.14.13.30;
DE   AltName: Full=CYPIVF2;
DE   AltName: Full=Cytochrome P450 4F2;
DE   AltName: Full=Cytochrome P450-LTB-omega;
DE   AltName: Full=Leukotriene-B(4) 20-monooxygenase 1;
GN   Name=CYP4F2;
DR   GO; GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0052869; F:arachidonic acid omega-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0052872; F:tocotrienol omega-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IMP:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0017144; P:drug metabolic process; IMP:UniProtKB.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.
DR   GO; GO:0006690; P:icosanoid metabolic process; TAS:Reactome.
DR   GO; GO:0036101; P:leukotriene B4 catabolic process; IDA:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IMP:UniProtKB.
DR   GO; GO:0032304; P:negative regulation of icosanoid secretion; IMP:UniProtKB.
DR   GO; GO:0097267; P:omega-hydroxylase P450 pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.
DR   GO; GO:0003095; P:pressure natriuresis; IEP:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:UniProtKB.
DR   GO; GO:0003091; P:renal water homeostasis; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042360; P:vitamin E metabolic process; IDA:UniProtKB.
DR   GO; GO:0042371; P:vitamin K biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4F3_HUMAN             Reviewed;         520 AA.
AC   Q08477; B7Z8Z3; O60634; Q5U740;
DE   RecName: Full=Leukotriene-B(4) omega-hydroxylase 2;
DE            EC=1.14.13.30;
DE   AltName: Full=CYPIVF3;
DE   AltName: Full=Cytochrome P450 4F3;
DE   AltName: Full=Cytochrome P450-LTB-omega;
DE   AltName: Full=Leukotriene-B(4) 20-monooxygenase 2;
GN   Name=CYP4F3; Synonyms=LTB4H;
DR   GO; GO:0052871; F:alpha-tocopherol omega-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004497; F:monooxygenase activity; TAS:ProtInc.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006690; P:icosanoid metabolic process; TAS:Reactome.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4FB_HUMAN             Reviewed;         524 AA.
AC   Q9HBI6; O75254; Q96AQ5;
DE   RecName: Full=Cytochrome P450 4F11;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIVF11;
GN   Name=CYP4F11;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; TAS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4F8_HUMAN             Reviewed;         520 AA.
AC   P98187;
DE   RecName: Full=Cytochrome P450 4F8;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIVF8;
GN   Name=CYP4F8;
DR   GO; GO:0018685; F:alkane 1-monooxygenase activity; TAS:ProtInc.
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0006690; P:icosanoid metabolic process; TAS:Reactome.
DR   GO; GO:0006693; P:prostaglandin metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4FC_HUMAN             Reviewed;         524 AA.
AC   Q9HCS2; O60389; Q9HCS1;
DE   RecName: Full=Cytochrome P450 4F12;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIVF12;
GN   Name=CYP4F12; ORFNames=UNQ568/PRO1129;
DR   GO; GO:0018685; F:alkane 1-monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0008392; F:arachidonic acid epoxygenase activity; ISS:UniProtKB.
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050051; F:leukotriene-B4 20-monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; ISS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0017144; P:drug metabolic process; ISS:UniProtKB.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; ISS:UniProtKB.
DR   GO; GO:0036101; P:leukotriene B4 catabolic process; ISS:UniProtKB.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:UniProtKB.
DR   GO; GO:0003095; P:pressure natriuresis; ISS:UniProtKB.
DR   GO; GO:0003091; P:renal water homeostasis; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055078; P:sodium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0042360; P:vitamin E metabolic process; ISS:UniProtKB.
DR   GO; GO:0042371; P:vitamin K biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP4FN_HUMAN             Reviewed;         531 AA.
AC   Q6NT55; Q8N8H4;
DE   RecName: Full=Cytochrome P450 4F22;
DE            EC=1.14.14.-;
GN   Name=CYP4F22;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
//
ID   CP4V2_HUMAN             Reviewed;         525 AA.
AC   Q6ZWL3; B7U6W2; Q6ZTM4;
DE   RecName: Full=Cytochrome P450 4V2;
DE            EC=1.14.13.-;
GN   Name=CYP4V2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0010430; P:fatty acid omega-oxidation; IDA:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   CP4X1_HUMAN             Reviewed;         509 AA.
AC   Q8N118; G3V1U1; Q5VVE5; Q6ZN67; Q8NAZ3;
DE   RecName: Full=Cytochrome P450 4X1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIVX1;
GN   Name=CYP4X1; ORFNames=UNQ1929/PRO4404;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
//
ID   CP4Z1_HUMAN             Reviewed;         505 AA.
AC   Q86W10; Q5VVE4;
DE   RecName: Full=Cytochrome P450 4Z1;
DE            EC=1.14.14.1;
DE   AltName: Full=CYPIVZ1;
GN   Name=CYP4Z1; ORFNames=UNQ3060/PRO9882;
DR   GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
//
ID   CP4Z2_HUMAN             Reviewed;         340 AA.
AC   Q8N1L4; Q66ZJ5;
DE   RecName: Full=Putative inactive cytochrome P450 family member 4Z2;
GN   Name=CYP4Z2P;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
//
ID   CP51A_HUMAN             Reviewed;         503 AA.
AC   Q16850; A4D1F8; B2RAI4; B4DJ55; O00770; O00772; Q16784; Q8N1A8;
AC   Q99868;
DE   RecName: Full=Lanosterol 14-alpha demethylase;
DE            Short=LDM;
DE            EC=1.14.13.70;
DE   AltName: Full=CYPLI;
DE   AltName: Full=Cytochrome P450 51A1;
DE   AltName: Full=Cytochrome P450-14DM;
DE            Short=Cytochrome P45014DM;
DE   AltName: Full=Cytochrome P450LI;
DE   AltName: Full=Sterol 14-alpha demethylase;
GN   Name=CYP51A1; Synonyms=CYP51;
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008398; F:sterol 14-demethylase activity; IDA:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0033488; P:cholesterol biosynthetic process via 24,25-dihydrolanosterol; IEA:Ensembl.
DR   GO; GO:0070988; P:demethylation; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP7A1_HUMAN             Reviewed;         504 AA.
AC   P22680; P78454; Q3MIL8; Q7KZ19;
DE   RecName: Full=Cholesterol 7-alpha-monooxygenase;
DE            EC=1.14.13.17;
DE   AltName: Full=CYPVII;
DE   AltName: Full=Cholesterol 7-alpha-hydroxylase;
DE   AltName: Full=Cytochrome P450 7A1;
GN   Name=CYP7A1; Synonyms=CYP7;
DR   GO; GO:0008123; F:cholesterol 7-alpha-monooxygenase activity; ISS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.
DR   GO; GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0070857; P:regulation of bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP7B1_HUMAN             Reviewed;         506 AA.
AC   O75881; B2RN07; Q9UNF5;
DE   RecName: Full=25-hydroxycholesterol 7-alpha-hydroxylase;
DE            EC=1.14.13.100;
DE   AltName: Full=Cytochrome P450 7B1;
DE   AltName: Full=Oxysterol 7-alpha-hydroxylase;
GN   Name=CYP7B1;
DR   GO; GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; TAS:ProtInc.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CP8B1_HUMAN             Reviewed;         501 AA.
AC   Q9UNU6; B2RCY3; O75958; Q6NWT2; Q6NWT3;
DE   RecName: Full=7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase;
DE            EC=1.14.13.95;
DE   AltName: Full=7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase;
DE   AltName: Full=CYPVIIIB1;
DE   AltName: Full=Cytochrome P450 8B1;
DE   AltName: Full=Sterol 12-alpha-hydroxylase;
GN   Name=CYP8B1; Synonyms=CYP12;
DR   GO; GO:0033778; F:7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IBA:RefGenome.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; TAS:ProtInc.
DR   GO; GO:0008397; F:sterol 12-alpha-hydroxylase activity; IBA:RefGenome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; IBA:RefGenome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016125; P:sterol metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   CPEB1_HUMAN             Reviewed;         566 AA.
AC   Q9BZB8; B7Z6C6; Q86W46; Q8IV41; Q9BZB7; Q9H8V5;
DE   RecName: Full=Cytoplasmic polyadenylation element-binding protein 1;
DE            Short=CPE-BP1;
DE            Short=CPE-binding protein 1;
DE            Short=h-CEBP;
DE            Short=hCPEB-1;
GN   Name=CPEB1; Synonyms=CPEB;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; ISS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; ISS:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:2000766; P:negative regulation of cytoplasmic translation; IMP:UniProtKB.
//
ID   CPEB2_HUMAN             Reviewed;         589 AA.
AC   Q7Z5Q1; Q3B8N6; Q3MI89; Q3MI90; Q3MI92; Q7Z5Q0;
DE   RecName: Full=Cytoplasmic polyadenylation element-binding protein 2;
DE            Short=CPE-BP2;
DE            Short=CPE-binding protein 2;
DE            Short=hCPEB-2;
GN   Name=CPEB2;
DR   GO; GO:0005095; F:GTPase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; ISS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043023; F:ribosomal large subunit binding; ISS:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; ISS:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; ISS:UniProtKB.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; ISS:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:2000766; P:negative regulation of cytoplasmic translation; IMP:UniProtKB.
DR   GO; GO:1900248; P:negative regulation of cytoplasmic translational elongation; ISS:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; ISS:UniProtKB.
//
ID   CPEB3_HUMAN             Reviewed;         698 AA.
AC   Q8NE35; Q5T389; Q9NQJ7; Q9Y2E9;
DE   RecName: Full=Cytoplasmic polyadenylation element-binding protein 3;
DE            Short=CPE-BP3;
DE            Short=CPE-binding protein 3;
DE            Short=hCPEB-3;
GN   Name=CPEB3; Synonyms=KIAA0940;
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; ISS:UniProtKB.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0035613; F:RNA stem-loop binding; ISS:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; ISS:UniProtKB.
DR   GO; GO:0061158; P:3'-UTR-mediated mRNA destabilization; IDA:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IDA:UniProtKB.
DR   GO; GO:0007616; P:long-term memory; ISS:UniProtKB.
DR   GO; GO:1900248; P:negative regulation of cytoplasmic translational elongation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.
DR   GO; GO:1900365; P:positive regulation of mRNA polyadenylation; ISS:UniProtKB.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; ISS:UniProtKB.
DR   GO; GO:0060998; P:regulation of dendritic spine development; ISS:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; IDA:GOC.
//
ID   CPEB4_HUMAN             Reviewed;         729 AA.
AC   Q17RY0; B7ZLQ7; Q7Z310; Q8N405; Q9C0J0;
DE   RecName: Full=Cytoplasmic polyadenylation element-binding protein 4;
DE            Short=CPE-BP4;
DE            Short=CPE-binding protein 4;
DE            Short=hCPEB-4;
GN   Name=CPEB4; Synonyms=KIAA1673;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0036294; P:cellular response to decreased oxygen levels; ISS:UniProtKB.
DR   GO; GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; ISS:UniProtKB.
//
ID   CPED1_HUMAN             Reviewed;        1026 AA.
AC   A4D0V7; A8K1R3; Q6UXT1; Q86T76; Q86T84; Q8N2T5; Q96NC9;
DE   RecName: Full=Cadherin-like and PC-esterase domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=CPED1; Synonyms=C7orf58; ORFNames=UNQ9432/PRO34713;
//
ID   CPIN1_HUMAN             Reviewed;         312 AA.
AC   Q6FI81; A8K8B6; O75206; O75207; Q9H0W1; Q9P1L7;
DE   RecName: Full=Anamorsin;
DE   AltName: Full=Cytokine-induced apoptosis inhibitor 1;
DE   AltName: Full=Fe-S cluster assembly protein DRE2 homolog;
GN   Name=CIAPIN1; ORFNames=CUA001, PRO0915;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009055; F:electron carrier activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030097; P:hemopoiesis; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CPLX1_HUMAN             Reviewed;         134 AA.
AC   O14810; A6NI80; B2R4R5; D3DVN3;
DE   RecName: Full=Complexin-1;
DE   AltName: Full=Complexin I;
DE            Short=CPX I;
DE   AltName: Full=Synaphin-2;
GN   Name=CPLX1;
DR   GO; GO:0005326; F:neurotransmitter transporter activity; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
//
ID   CPLX2_HUMAN             Reviewed;         134 AA.
AC   Q6PUV4; B2RAG2; O09056; Q13329; Q28184; Q52M15; Q64386;
DE   RecName: Full=Complexin-2;
DE   AltName: Full=Complexin II;
DE            Short=CPX II;
DE   AltName: Full=Synaphin-1;
GN   Name=CPLX2;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043303; P:mast cell degranulation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; TAS:ProtInc.
//
ID   CPLX4_HUMAN             Reviewed;         160 AA.
AC   Q7Z7G2; F1T0L6;
DE   RecName: Full=Complexin-4;
DE   AltName: Full=Complexin IV;
DE            Short=CPX IV;
DE   Flags: Precursor;
GN   Name=CPLX4;
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
//
ID   CPLX3_HUMAN             Reviewed;         158 AA.
AC   Q8WVH0; D3DW66; Q8TEM6; Q9H818;
DE   RecName: Full=Complexin-3;
DE   AltName: Full=Complexin III;
DE            Short=CPX III;
DE   Flags: Precursor;
GN   Name=CPLX3; ORFNames=Nbla11589;
DR   GO; GO:0005326; F:neurotransmitter transporter activity; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
//
ID   CPMD8_HUMAN             Reviewed;        1885 AA.
AC   Q8IZJ3; Q8NC09; Q9ULD7;
DE   RecName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8;
DE   Flags: Precursor;
GN   Name=CPAMD8; Synonyms=KIAA1283;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   CPN2_HUMAN              Reviewed;         545 AA.
AC   P22792; B2RPE7; Q86SU4; Q8N5V4;
DE   RecName: Full=Carboxypeptidase N subunit 2;
DE   AltName: Full=Carboxypeptidase N 83 kDa chain;
DE   AltName: Full=Carboxypeptidase N large subunit;
DE   AltName: Full=Carboxypeptidase N polypeptide 2;
DE   AltName: Full=Carboxypeptidase N regulatory subunit;
DE   Flags: Precursor;
GN   Name=CPN2; Synonyms=ACBP;
DR   GO; GO:0030234; F:enzyme regulator activity; NAS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; NAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; NAS:GOC.
//
ID   CPNE1_HUMAN             Reviewed;         537 AA.
AC   Q99829; E1P5Q4; Q6IBL3; Q9H243; Q9NTZ7;
DE   RecName: Full=Copine-1;
DE   AltName: Full=Copine I;
GN   Name=CPNE1; Synonyms=CPN1;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; TAS:ProtInc.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:MGI.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   CPNE2_HUMAN             Reviewed;         548 AA.
AC   Q96FN4; Q68D19; Q86XP9;
DE   RecName: Full=Copine-2;
DE   AltName: Full=Copine II;
GN   Name=CPNE2;
//
ID   CPNE3_HUMAN             Reviewed;         537 AA.
AC   O75131; A8KA47; Q8IYA1;
DE   RecName: Full=Copine-3;
DE   AltName: Full=Copine III;
GN   Name=CPNE3; Synonyms=CPN3, KIAA0636;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   CPNE4_HUMAN             Reviewed;         557 AA.
AC   Q96A23; D3DNC5; Q8TEX1;
DE   RecName: Full=Copine-4;
DE   AltName: Full=Copine IV;
DE   AltName: Full=Copine-8;
GN   Name=CPNE4;
//
ID   CPNE5_HUMAN             Reviewed;         593 AA.
AC   Q9HCH3;
DE   RecName: Full=Copine-5;
DE   AltName: Full=Copine V;
GN   Name=CPNE5; Synonyms=KIAA1599;
//
ID   CPNE6_HUMAN             Reviewed;         557 AA.
AC   O95741; B2RAG6; B7Z1M3; D3DS55; F5GXN1; Q53HA6; Q8WVG1;
DE   RecName: Full=Copine-6;
DE   AltName: Full=Copine VI;
DE   AltName: Full=Neuronal-copine;
DE            Short=N-copine;
GN   Name=CPNE6;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   CPNE7_HUMAN             Reviewed;         633 AA.
AC   Q9UBL6;
DE   RecName: Full=Copine-7;
DE   AltName: Full=Copine VII;
GN   Name=CPNE7;
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:GOC.
//
ID   CPNE8_HUMAN             Reviewed;         564 AA.
AC   Q86YQ8; Q2TB41;
DE   RecName: Full=Copine-8;
DE   AltName: Full=Copine VIII;
GN   Name=CPNE8;
//
ID   CPNE9_HUMAN             Reviewed;         553 AA.
AC   Q8IYJ1; A1L430; A6NDX6; A8MSP8;
DE   RecName: Full=Copine-9;
DE   AltName: Full=Copine IX;
GN   Name=CPNE9;
//
ID   CPNS1_HUMAN             Reviewed;         268 AA.
AC   P04632; A8K0P1; Q8WTX3; Q96EW0;
DE   RecName: Full=Calpain small subunit 1;
DE            Short=CSS1;
DE   AltName: Full=Calcium-activated neutral proteinase small subunit;
DE            Short=CANP small subunit;
DE   AltName: Full=Calcium-dependent protease small subunit;
DE            Short=CDPS;
DE   AltName: Full=Calcium-dependent protease small subunit 1;
DE   AltName: Full=Calpain regulatory subunit;
GN   Name=CAPNS1; Synonyms=CAPN4, CAPNS;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CPNS2_HUMAN             Reviewed;         248 AA.
AC   Q96L46; Q9BPV4;
DE   RecName: Full=Calpain small subunit 2;
DE            Short=CSS2;
DE   AltName: Full=Calcium-dependent protease small subunit 2;
GN   Name=CAPNS2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   CPPED_HUMAN             Reviewed;         314 AA.
AC   Q9BRF8; Q6MZY9; Q9H9M9; Q9NUT6;
DE   RecName: Full=Calcineurin-like phosphoesterase domain-containing protein 1;
DE            EC=3.1.-.-;
DE   AltName: Full=Complete S-transactivated protein 1;
GN   Name=CPPED1; Synonyms=CSTP1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   CPS4L_HUMAN             Reviewed;         179 AA.
AC   A6NMK7; A8MU95; B2RXI9;
DE   RecName: Full=Putative cleavage and polyadenylation specificity factor subunit 4-like protein;
GN   Name=CPSF4L;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   CPSF1_HUMAN             Reviewed;        1443 AA.
AC   Q10570; Q96AF0;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 1;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 160 kDa subunit;
DE            Short=CPSF 160 kDa subunit;
GN   Name=CPSF1; Synonyms=CPSF160;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006378; P:mRNA polyadenylation; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CPSF2_HUMAN             Reviewed;         782 AA.
AC   Q9P2I0; B3KME1; Q6NSJ1; Q9H3W7;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 2;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 100 kDa subunit;
DE            Short=CPSF 100 kDa subunit;
GN   Name=CPSF2; Synonyms=CPSF100, KIAA1367;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006398; P:histone mRNA 3'-end processing; IDA:UniProtKB.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; IEA:InterPro.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CPSF3_HUMAN             Reviewed;         684 AA.
AC   Q9UKF6; O14769; Q53RS2; Q96F36;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 3;
DE            EC=3.1.27.-;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 73 kDa subunit;
DE            Short=CPSF 73 kDa subunit;
DE   AltName: Full=mRNA 3'-end-processing endonuclease CPSF-73;
GN   Name=CPSF3; Synonyms=CPSF73;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; ISS:UniProtKB.
DR   GO; GO:0004521; F:endoribonuclease activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006398; P:histone mRNA 3'-end processing; IDA:UniProtKB.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; TAS:ProtInc.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; ISS:GOC.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CPSF4_HUMAN             Reviewed;         269 AA.
AC   O95639; D6W5S8; Q6FGE6; Q86TF8; Q9BTW6;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 4;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 30 kDa subunit;
DE            Short=CPSF 30 kDa subunit;
DE   AltName: Full=NS1 effector domain-binding protein 1;
DE            Short=Neb-1;
DE   AltName: Full=No arches homolog;
GN   Name=CPSF4; Synonyms=CPSF30, NAR, NEB1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046778; P:modification by virus of host mRNA processing; TAS:Reactome.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:Reactome.
DR   GO; GO:0019054; P:modulation by virus of host process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
//
ID   CPSF5_HUMAN             Reviewed;         227 AA.
AC   O43809; Q6IB85; Q6NE84;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 5;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 25 kDa subunit;
DE            Short=CFIm25;
DE            Short=CPSF 25 kDa subunit;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 21;
DE            Short=Nudix motif 21;
DE   AltName: Full=Pre-mRNA cleavage factor Im 25 kDa subunit;
GN   Name=NUDT21; Synonyms=CFIM25, CPSF25, CPSF5;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CPSF6_HUMAN             Reviewed;         551 AA.
AC   Q16630; A8K7K9; Q53ES1; Q9BSJ7; Q9BW18;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 6;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 68 kDa subunit;
DE            Short=CFIm68;
DE            Short=CPSF 68 kDa subunit;
DE   AltName: Full=Pre-mRNA cleavage factor Im 68 kDa subunit;
DE   AltName: Full=Protein HPBRII-4/7;
GN   Name=CPSF6; Synonyms=CFIM68;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
//
ID   CPSF7_HUMAN             Reviewed;         471 AA.
AC   Q8N684; B3KU04; C9K0Q4; Q7Z3H9; Q9H025; Q9H9V1;
DE   RecName: Full=Cleavage and polyadenylation specificity factor subunit 7;
DE   AltName: Full=Cleavage and polyadenylation specificity factor 59 kDa subunit;
DE            Short=CFIm59;
DE            Short=CPSF 59 kDa subunit;
DE   AltName: Full=Pre-mRNA cleavage factor Im 59 kDa subunit;
GN   Name=CPSF7;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CPSM_HUMAN              Reviewed;        1500 AA.
AC   P31327; B7Z818; J3KQL0; O43774; Q53TL5; Q59HF8; Q7Z5I5;
DE   RecName: Full=Carbamoyl-phosphate synthase [ammonia], mitochondrial;
DE            EC=6.3.4.16;
DE   AltName: Full=Carbamoyl-phosphate synthetase I;
DE            Short=CPSase I;
DE   Flags: Precursor;
GN   Name=CPS1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IMP:BHF-UCL.
DR   GO; GO:0004175; F:endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0055081; P:anion homeostasis; IEA:Ensembl.
DR   GO; GO:0070409; P:carbamoyl phosphate biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; IEA:Ensembl.
DR   GO; GO:0071400; P:cellular response to oleic acid; IEA:Ensembl.
DR   GO; GO:0019240; P:citrulline biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0006543; P:glutamine catabolic process; IEA:InterPro.
DR   GO; GO:0005980; P:glycogen catabolic process; IMP:BHF-UCL.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0007494; P:midgut development; IEA:Ensembl.
DR   GO; GO:0046209; P:nitric oxide metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IMP:BHF-UCL.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0071548; P:response to dexamethasone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0060416; P:response to growth hormone; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; IMP:BHF-UCL.
DR   GO; GO:0000050; P:urea cycle; NAS:BHF-UCL.
//
ID   CPT1A_HUMAN             Reviewed;         773 AA.
AC   P50416; Q8TCU0; Q9BWK0;
DE   RecName: Full=Carnitine O-palmitoyltransferase 1, liver isoform;
DE            Short=CPT1-L;
DE            EC=2.3.1.21;
DE   AltName: Full=Carnitine O-palmitoyltransferase I, liver isoform;
DE            Short=CPT I;
DE            Short=CPTI-L;
DE   AltName: Full=Carnitine palmitoyltransferase 1A;
GN   Name=CPT1A; Synonyms=CPT1;
DR   GO; GO:0004095; F:carnitine O-palmitoyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0009437; P:carnitine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   CPT1B_HUMAN             Reviewed;         772 AA.
AC   Q92523; B7Z4U4; B7Z5T8; E9PCP2; Q13389; Q99655; Q9BY90;
DE   RecName: Full=Carnitine O-palmitoyltransferase 1, muscle isoform;
DE            Short=CPT1-M;
DE            EC=2.3.1.21;
DE   AltName: Full=Carnitine O-palmitoyltransferase I, muscle isoform;
DE            Short=CPT I;
DE            Short=CPTI-M;
DE   AltName: Full=Carnitine palmitoyltransferase 1B;
DE   AltName: Full=Carnitine palmitoyltransferase I-like protein;
GN   Name=CPT1B; Synonyms=KIAA1670;
DR   GO; GO:0004095; F:carnitine O-palmitoyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CPT1C_HUMAN             Reviewed;         803 AA.
AC   Q8TCG5; A8K0Z8; Q5K6N5; Q8N6Q9; Q8NDS6; Q8TE84;
DE   RecName: Full=Carnitine O-palmitoyltransferase 1, brain isoform;
DE            Short=CPT1-B;
DE            EC=2.3.1.21;
DE   AltName: Full=CPT IC;
DE   AltName: Full=Carnitine O-palmitoyltransferase I, brain isoform;
DE            Short=CPTI-B;
DE   AltName: Full=Carnitine palmitoyltransferase 1C;
GN   Name=CPT1C; Synonyms=CATL1;
DR   GO; GO:0004095; F:carnitine O-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:Ensembl.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
//
ID   CPT2_HUMAN              Reviewed;         658 AA.
AC   P23786; B2R6S0; Q5SW68; Q9BQ26;
DE   RecName: Full=Carnitine O-palmitoyltransferase 2, mitochondrial;
DE            EC=2.3.1.21;
DE   AltName: Full=Carnitine palmitoyltransferase II;
DE            Short=CPT II;
DE   Flags: Precursor;
GN   Name=CPT2; Synonyms=CPT1;
DR   GO; GO:0004095; F:carnitine O-palmitoyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CPTP_HUMAN              Reviewed;         214 AA.
AC   Q5TA50; Q4G0E6; Q7L5A4;
DE   RecName: Full=Ceramide-1-phosphate transfer protein;
DE            Short=CPTP;
DE   AltName: Full=Glycolipid transfer protein domain-containing protein 1;
DE            Short=GLTP domain-containing protein 1;
GN   Name=GLTPD1;
DR   GO; GO:1902387; F:ceramide 1-phosphate binding; IDA:UniProtKB.
DR   GO; GO:1902388; F:ceramide 1-phosphate transporter activity; IDA:UniProtKB.
DR   GO; GO:0051861; F:glycolipid binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005548; F:phospholipid transporter activity; IDA:UniProtKB.
DR   GO; GO:1902389; P:ceramide 1-phosphate transport; IDA:UniProtKB.
//
ID   CPVL_HUMAN              Reviewed;         476 AA.
AC   Q9H3G5; A4D1A4; Q6UX20; Q8NBL7; Q96AR7; Q9HB41;
DE   RecName: Full=Probable serine carboxypeptidase CPVL;
DE            EC=3.4.16.-;
DE   AltName: Full=Carboxypeptidase, vitellogenic-like;
DE   AltName: Full=Vitellogenic carboxypeptidase-like protein;
DE            Short=VCP-like protein;
DE            Short=hVLP;
DE   Flags: Precursor;
GN   Name=CPVL; Synonyms=VLP; ORFNames=PSEC0124, UNQ197/PRO223;
DR   GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
//
ID   CPXCR_HUMAN             Reviewed;         301 AA.
AC   Q8N123; B2R9F9; D3DTE7; Q96RS3;
DE   RecName: Full=CPX chromosomal region candidate gene 1 protein;
DE   AltName: Full=Cancer/testis antigen 77;
DE            Short=CT77;
GN   Name=CPXCR1;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
//
ID   CPXM1_HUMAN             Reviewed;         734 AA.
AC   Q96SM3; Q6P4G8; Q6UW65; Q9NUB5;
DE   RecName: Full=Probable carboxypeptidase X1;
DE            EC=3.4.17.-;
DE   AltName: Full=Metallocarboxypeptidase CPX-1;
DE   Flags: Precursor;
GN   Name=CPXM1; Synonyms=CPX1, CPXM; ORFNames=UNQ3015/PRO9782;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   CPXM2_HUMAN             Reviewed;         756 AA.
AC   Q8N436; B4E3Q2;
DE   RecName: Full=Inactive carboxypeptidase-like protein X2;
DE   Flags: Precursor;
GN   Name=CPXM2; ORFNames=UNQ676/PRO1310;
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   CPZIP_HUMAN             Reviewed;         416 AA.
AC   Q6JBY9; B1AK48; Q4G0E7; Q6IN93; Q8IZM2; Q96DX0; Q9NST4;
DE   RecName: Full=CapZ-interacting protein;
DE   AltName: Full=Protein kinase substrate CapZIP;
DE   AltName: Full=RCSD domain-containing protein 1;
GN   Name=RCSD1; Synonyms=CAPZIP;
DR   GO; GO:0051015; F:actin filament binding; IPI:BHF-UCL.
DR   GO; GO:0071474; P:cellular hyperosmotic response; IDA:BHF-UCL.
DR   GO; GO:0003009; P:skeletal muscle contraction; ISS:BHF-UCL.
//
ID   CQ047_HUMAN             Reviewed;         570 AA.
AC   Q8NEP4; Q8N821;
DE   RecName: Full=Uncharacterized protein C17orf47;
GN   Name=C17orf47;
//
ID   CQ050_HUMAN             Reviewed;         174 AA.
AC   Q8WW18; Q6Q621;
DE   RecName: Full=Uncharacterized protein C17orf50;
GN   Name=C17orf50;
//
ID   CQ051_HUMAN             Reviewed;         221 AA.
AC   A8MQB3; B2RN29; B5MCL4;
DE   RecName: Full=Uncharacterized protein C17orf51;
GN   Name=C17orf51;
//
ID   CQ053_HUMAN             Reviewed;         647 AA.
AC   Q8N3J3; A8K7A9; Q9BWM9; Q9HAI1;
DE   RecName: Full=Uncharacterized protein C17orf53;
GN   Name=C17orf53;
//
ID   CQ054_HUMAN             Reviewed;         141 AA.
AC   Q8N7U9; Q495E4;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00469;
GN   Name=LINC00469; Synonyms=C17orf54;
//
ID   CQ055_HUMAN             Reviewed;         264 AA.
AC   Q8N8I6;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00482;
GN   Name=LINC00482; Synonyms=C17orf55;
//
ID   CQ058_HUMAN             Reviewed;          97 AA.
AC   Q2M2W7; A8MQV2;
DE   RecName: Full=UPF0450 protein C17orf58;
GN   Name=C17orf58;
//
ID   CQ059_HUMAN             Reviewed;         357 AA.
AC   Q96GS4; Q53HS4; Q9NXW8;
DE   RecName: Full=Uncharacterized protein C17orf59;
GN   Name=C17orf59;
//
ID   CQ062_HUMAN             Reviewed;         187 AA.
AC   Q9BQA9; E1B6X3; Q96NR1;
DE   RecName: Full=Uncharacterized protein C17orf62;
GN   Name=C17orf62;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CQ064_HUMAN             Reviewed;         236 AA.
AC   Q86WR6; Q8IY87;
DE   RecName: Full=Uncharacterized protein C17orf64;
GN   Name=C17orf64;
//
ID   CQ066_HUMAN             Reviewed;         570 AA.
AC   A2RTY3; B4DX21; B4DXA4; B4DXF0; Q8N4R4; Q96M46;
DE   RecName: Full=Uncharacterized protein C17orf66;
GN   Name=C17orf66;
//
ID   CQ067_HUMAN             Reviewed;         114 AA.
AC   Q0P5P2;
DE   RecName: Full=Uncharacterized protein C17orf67;
DE   Flags: Precursor;
GN   Name=C17orf67;
//
ID   CQ073_HUMAN             Reviewed;         154 AA.
AC   Q53H64; Q9NWQ1;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00483;
GN   Name=LINC00483; Synonyms=C17orf73;
//
ID   CQ074_HUMAN             Reviewed;         501 AA.
AC   Q0P670;
DE   RecName: Full=Uncharacterized protein C17orf74;
GN   Name=C17orf74;
//
ID   CQ078_HUMAN             Reviewed;         275 AA.
AC   Q8N4C9; Q8N8D2;
DE   RecName: Full=Uncharacterized protein C17orf78;
GN   Name=C17orf78;
//
ID   CQ077_HUMAN             Reviewed;         243 AA.
AC   Q96MU5;
DE   RecName: Full=Uncharacterized protein C17orf77;
DE   Flags: Precursor;
GN   Name=C17orf77;
//
ID   CQ080_HUMAN             Reviewed;         609 AA.
AC   Q9BSJ5; A8K9X3; Q5JB45; Q6YAU3; Q9H0L9; Q9H5E6; Q9NWN5;
DE   RecName: Full=Uncharacterized protein C17orf80;
DE   AltName: Full=Cell migration-inducing gene 3 protein;
DE   AltName: Full=Human lung cancer oncogene 8 protein;
DE            Short=HLC-8;
GN   Name=C17orf80; ORFNames=HLC8, MIG3;
//
ID   CQ085_HUMAN             Reviewed;         620 AA.
AC   Q53F19; B3KWG7; Q7L406; Q96FK1; Q9NXZ4;
DE   RecName: Full=Uncharacterized protein C17orf85;
DE   AltName: Full=Protein ELG;
GN   Name=C17orf85;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CQ082_HUMAN             Reviewed;         251 AA.
AC   Q86X59;
DE   RecName: Full=Putative uncharacterized protein C17orf82;
GN   Name=C17orf82;
//
ID   CQ089_HUMAN             Reviewed;          74 AA.
AC   A1L188;
DE   RecName: Full=Uncharacterized protein C17orf89;
GN   Name=C17orf89;
//
ID   CQ091_HUMAN             Reviewed;          57 AA.
AC   Q0VDD5; Q0VDD6;
DE   RecName: Full=Putative uncharacterized protein encoded by MIR22HG;
GN   Name=MIR22HG; Synonyms=C17orf91;
//
ID   CQ096_HUMAN             Reviewed;         379 AA.
AC   A6NHQ4;
DE   RecName: Full=Uncharacterized protein C17orf96;
GN   Name=C17orf96;
//
ID   CQ097_HUMAN             Reviewed;         453 AA.
AC   Q6ZQX7; A5D8T6; Q6NSI2; Q6PFW9;
DE   RecName: Full=Uncharacterized protein C17orf97;
GN   Name=C17orf97;
//
ID   CQ099_HUMAN             Reviewed;         265 AA.
AC   Q6UX52;
DE   RecName: Full=Uncharacterized protein C17orf99;
DE   Flags: Precursor;
GN   Name=C17orf99; ORFNames=UNQ464/PRO809;
//
ID   CQ098_HUMAN             Reviewed;         154 AA.
AC   A8MV24;
DE   RecName: Full=Uncharacterized protein C17orf98;
GN   Name=C17orf98;
//
ID   CQ100_HUMAN             Reviewed;         164 AA.
AC   A8MU93;
DE   RecName: Full=Uncharacterized protein C17orf100;
GN   Name=C17orf100;
//
ID   CQ104_HUMAN             Reviewed;         952 AA.
AC   A2RUB1; B4DXJ2; B5MD93; B9EGQ6; C4AM97; Q4G0Y1; Q8IVZ7; Q8NA45;
DE   RecName: Full=Uncharacterized protein C17orf104;
GN   Name=C17orf104;
//
ID   CQ102_HUMAN             Reviewed;         167 AA.
AC   A2RUQ5; A5PKX0; Q6ZTB3;
DE   RecName: Full=Uncharacterized protein C17orf102;
GN   Name=C17orf102;
//
ID   CQ105_HUMAN             Reviewed;         164 AA.
AC   B2RV13;
DE   RecName: Full=Uncharacterized protein C17orf105;
GN   Name=C17orf105;
//
ID   CQ107_HUMAN             Reviewed;         190 AA.
AC   Q6ZR85;
DE   RecName: Full=Uncharacterized protein C17orf107;
GN   Name=C17orf107;
//
ID   CQ10A_HUMAN             Reviewed;         247 AA.
AC   Q96MF6; Q6GMR6; Q6UWB9; Q86X16; Q8TAL2; Q96MF1; Q9BUP4;
DE   RecName: Full=Coenzyme Q-binding protein COQ10 homolog A, mitochondrial;
DE   Flags: Precursor;
GN   Name=COQ10A; ORFNames=UNQ6192/PRO20219;
//
ID   CQ10B_HUMAN             Reviewed;         238 AA.
AC   Q9H8M1;
DE   RecName: Full=Coenzyme Q-binding protein COQ10 homolog B, mitochondrial;
DE   Flags: Precursor;
GN   Name=COQ10B;
//
ID   CQ112_HUMAN             Reviewed;         114 AA.
AC   F2Z3M2;
DE   RecName: Full=Uncharacterized protein C17orf112;
GN   Name=C17orf112;
//
ID   CR002_HUMAN             Reviewed;          86 AA.
AC   Q9BZP3; Q9BZP2; Q9BZP4;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00470;
GN   Name=LINC00470; Synonyms=C18orf2;
//
ID   CR012_HUMAN             Reviewed;         178 AA.
AC   Q96KH6;
DE   RecName: Full=Uncharacterized protein C18orf12;
DE   AltName: Full=Protein HEIL1;
GN   Name=C18orf12;
//
ID   CR015_HUMAN             Reviewed;         181 AA.
AC   Q96N68;
DE   RecName: Full=Putative uncharacterized protein C18orf15;
GN   Name=C18orf15;
//
ID   CR018_HUMAN             Reviewed;          95 AA.
AC   Q96FQ7; A8K9M8;
DE   RecName: Full=Putative uncharacterized protein encoded LINC00526;
GN   Name=LINC00526; Synonyms=C18orf18;
//
ID   CR021_HUMAN             Reviewed;         220 AA.
AC   Q32NC0; Q6GW03; Q9BXV6; Q9BXW2;
DE   RecName: Full=UPF0711 protein C18orf21;
DE   AltName: Full=HBV X-transactivated gene 13 protein;
DE   AltName: Full=HBV XAg-transactivated protein 13;
GN   Name=C18orf21; Synonyms=XTP13; ORFNames=PNAS-124, PNAS-131;
//
ID   CR020_HUMAN             Reviewed;         112 AA.
AC   Q7Z4B0; Q8NHR5;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00305;
DE   Flags: Precursor;
GN   Name=LINC00305; Synonyms=C18orf20, NCRNA00305;
//
ID   CR025_HUMAN             Reviewed;         403 AA.
AC   Q96B23; A8K123; A8KAB6; Q5XG78; Q6N058; Q86TB5; Q8TCQ5;
DE   RecName: Full=Uncharacterized protein C18orf25;
GN   Name=C18orf25;
//
ID   CR032_HUMAN             Reviewed;          76 AA.
AC   Q8TCD1;
DE   RecName: Full=UPF0729 protein C18orf32;
DE   AltName: Full=Putative NF-kappa-B-activating protein 200;
GN   Name=C18orf32;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   CR042_HUMAN             Reviewed;          69 AA.
AC   P0CW23;
DE   RecName: Full=Putative uncharacterized protein C18orf42;
GN   Name=C18orf42;
//
ID   CR056_HUMAN             Reviewed;         123 AA.
AC   Q8TAI1; A8K1S1;
DE   RecName: Full=Putative uncharacterized protein C18orf56;
GN   Name=C18orf56;
//
ID   CR063_HUMAN             Reviewed;         685 AA.
AC   Q68DL7; A6NME8;
DE   RecName: Full=Uncharacterized protein C18orf63;
GN   Name=C18orf63;
//
ID   CR064_HUMAN             Reviewed;         135 AA.
AC   J3KSC0;
DE   RecName: Full=Putative uncharacterized protein C18orf64;
GN   Name=C18orf64;
//
ID   CR1L_HUMAN              Reviewed;         569 AA.
AC   Q2VPA4; Q32MC9; Q8NEU7;
DE   RecName: Full=Complement component receptor 1-like protein;
DE   AltName: Full=Complement C4b-binding protein CR-1-like protein;
DE   Flags: Precursor;
GN   Name=CR1L;
//
ID   CR1_HUMAN               Reviewed;        2039 AA.
AC   P17927; Q16744; Q16745; Q5SR43; Q5SR45; Q9UQV2;
DE   RecName: Full=Complement receptor type 1;
DE   AltName: Full=C3b/C4b receptor;
DE   AltName: CD_antigen=CD35;
DE   Flags: Precursor;
GN   Name=CR1; Synonyms=C3BR;
DR   GO; GO:0001851; F:complement component C3b binding; IDA:UniProtKB.
DR   GO; GO:0004877; F:complement component C3b receptor activity; IDA:UniProtKB.
DR   GO; GO:0001855; F:complement component C4b binding; IDA:UniProtKB.
DR   GO; GO:0001861; F:complement component C4b receptor activity; IDA:UniProtKB.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0002430; P:complement receptor mediated signaling pathway; IDA:GOC.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045957; P:negative regulation of complement activation, alternative pathway; IDA:UniProtKB.
DR   GO; GO:0045959; P:negative regulation of complement activation, classical pathway; IDA:UniProtKB.
DR   GO; GO:1900004; P:negative regulation of serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:1900005; P:positive regulation of serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   CR2_HUMAN               Reviewed;        1033 AA.
AC   P20023; C9JHD2; Q13866; Q14212; Q53EL2; Q5BKT9; Q5SR46; Q5SR48;
DE   RecName: Full=Complement receptor type 2;
DE            Short=Cr2;
DE   AltName: Full=Complement C3d receptor;
DE   AltName: Full=Epstein-Barr virus receptor;
DE            Short=EBV receptor;
DE   AltName: CD_antigen=CD21;
DE   Flags: Precursor;
GN   Name=CR2; Synonyms=C3DR;
DR   GO; GO:0001848; F:complement binding; IDA:UniProt.
DR   GO; GO:0004875; F:complement receptor activity; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IDA:UniProt.
DR   GO; GO:0042100; P:B cell proliferation; IDA:UniProt.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   CR3L1_HUMAN             Reviewed;         519 AA.
AC   Q96BA8; Q8N2D5; Q96CP0;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 1;
DE            Short=cAMP-responsive element-binding protein 3-like protein 1;
DE   AltName: Full=Old astrocyte specifically-induced substance;
DE            Short=OASIS;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-responsive element-binding protein 3-like protein 1;
GN   Name=CREB3L1; Synonyms=OASIS; ORFNames=PSEC0238;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   CR3L2_HUMAN             Reviewed;         520 AA.
AC   Q70SY1; Q6P454; Q6ZMR6;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 2;
DE            Short=cAMP-responsive element-binding protein 3-like protein 2;
DE   AltName: Full=BBF2 human homolog on chromosome 7;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-responsive element-binding protein 3-like protein 2;
GN   Name=CREB3L2; Synonyms=BBF2H7;
DR   GO; GO:0035497; F:cAMP response element binding; IMP:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEP:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CR3L3_HUMAN             Reviewed;         461 AA.
AC   Q68CJ9; B2R7S6; B7ZL69; Q6ZMC5; Q96TB9;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 3;
DE            Short=cAMP-responsive element-binding protein 3-like protein 3;
DE   AltName: Full=Transcription factor CREB-H;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-responsive element-binding protein 3-like protein 3;
GN   Name=CREB3L3; Synonyms=CREBH; ORFNames=HYST1481;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CR3L4_HUMAN             Reviewed;         395 AA.
AC   Q8TEY5; D3DV62; Q5T4L0; Q86YW6;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 4;
DE            Short=cAMP-responsive element-binding protein 3-like protein 4;
DE   AltName: Full=Androgen-induced basic leucine zipper protein;
DE            Short=AIbZIP;
DE   AltName: Full=Attaching to CRE-like 1;
DE            Short=ATCE1;
DE   AltName: Full=Cyclic AMP-responsive element-binding protein 4;
DE            Short=CREB-4;
DE            Short=cAMP-responsive element-binding protein 4;
DE   AltName: Full=Transcript induced in spermiogenesis protein 40;
DE            Short=Tisp40;
DE   AltName: Full=hJAL;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-responsive element-binding protein 3-like protein 4;
GN   Name=CREB3L4; Synonyms=AIBZIP, CREB4, JAL;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CRAC1_HUMAN             Reviewed;         661 AA.
AC   Q9NQ79; B1ALN4; Q5T4F8; Q8N4H6; Q8TE52; Q9NQ78; Q9NQ80; Q9NW46;
DE   RecName: Full=Cartilage acidic protein 1;
DE   AltName: Full=68 kDa chondrocyte-expressed protein;
DE            Short=CEP-68;
DE   AltName: Full=ASPIC;
DE   Flags: Precursor;
GN   Name=CRTAC1; Synonyms=ASPIC1, CEP68;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   CRADD_HUMAN             Reviewed;         199 AA.
AC   P78560;
DE   RecName: Full=Death domain-containing protein CRADD;
DE   AltName: Full=Caspase and RIP adapter with death domain;
DE   AltName: Full=RIP-associated protein with a death domain;
GN   Name=CRADD; Synonyms=RAIDD;
DR   GO; GO:0070513; F:death domain binding; IPI:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; IPI:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IC:BHF-UCL.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
//
ID   CRAS1_HUMAN             Reviewed;         109 AA.
AC   A6NIL9; B3KVZ2;
DE   RecName: Full=Putative uncharacterized protein CRYM-AS1;
DE   AltName: Full=CRYM antisense RNA 1;
DE   AltName: Full=CRYM antisense gene protein 1;
GN   Name=CRYM-AS1; Synonyms=NCRNA00169;
//
ID   CRBA1_HUMAN             Reviewed;         215 AA.
AC   P05813; Q13633; Q14CM9;
DE   RecName: Full=Beta-crystallin A3;
DE   Contains:
DE     RecName: Full=Beta-crystallin A3, isoform A1, Delta4 form;
DE   Contains:
DE     RecName: Full=Beta-crystallin A3, isoform A1, Delta7 form;
DE   Contains:
DE     RecName: Full=Beta-crystallin A3, isoform A1, Delta8 form;
GN   Name=CRYBA1; Synonyms=CRYB1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CRBA2_HUMAN             Reviewed;         197 AA.
AC   P53672; Q4ZFX0; Q9Y562;
DE   RecName: Full=Beta-crystallin A2;
DE   AltName: Full=Beta-A2 crystallin;
GN   Name=CRYBA2;
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
//
ID   CRBA4_HUMAN             Reviewed;         196 AA.
AC   P53673; Q4VB22; Q6ICE4;
DE   RecName: Full=Beta-crystallin A4;
DE   AltName: Full=Beta-A4 crystallin;
GN   Name=CRYBA4;
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0043010; P:camera-type eye development; IMP:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CRBB1_HUMAN             Reviewed;         252 AA.
AC   P53674;
DE   RecName: Full=Beta-crystallin B1;
DE   AltName: Full=Beta-B1 crystallin;
GN   Name=CRYBB1;
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CRBB2_HUMAN             Reviewed;         205 AA.
AC   P43320; Q9UCM8;
DE   RecName: Full=Beta-crystallin B2;
DE   AltName: Full=Beta-B2 crystallin;
DE   AltName: Full=Beta-crystallin Bp;
GN   Name=CRYBB2; Synonyms=CRYB2, CRYB2A;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CRBB3_HUMAN             Reviewed;         211 AA.
AC   P26998; Q3B7S9; Q3T1B7; Q6ISK6; Q92965; Q9UH09;
DE   RecName: Full=Beta-crystallin B3;
DE   AltName: Full=Beta-B3 crystallin;
DE   Contains:
DE     RecName: Full=Beta-crystallin B3, N-terminally processed;
GN   Name=CRYBB3; Synonyms=CRYB3;
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CRBG3_HUMAN             Reviewed;        1022 AA.
AC   Q68DQ2; Q4G0V8; Q7Z4R9; Q86VD0; Q8N262; Q8N7F1; Q8NDQ8;
DE   RecName: Full=Beta/gamma crystallin domain-containing protein 3;
GN   Name=CRYBG3;
//
ID   CRBL2_HUMAN             Reviewed;         120 AA.
AC   O60519; B5BUM5;
DE   RecName: Full=cAMP-responsive element-binding protein-like 2;
GN   Name=CREBL2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; ISS:UniProtKB.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   CRBN_HUMAN              Reviewed;         442 AA.
AC   Q96SW2; B2R6H4; C9IZA9; C9JAH6; Q6AI62; Q6NVZ0; Q9UHW4;
DE   RecName: Full=Protein cereblon;
GN   Name=CRBN; ORFNames=AD-006;
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034766; P:negative regulation of ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0032463; P:negative regulation of protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0090073; P:positive regulation of protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
//
ID   CRBS_HUMAN              Reviewed;         178 AA.
AC   P22914; B2RAF8;
DE   RecName: Full=Beta-crystallin S;
DE   AltName: Full=Gamma-S-crystallin;
DE   AltName: Full=Gamma-crystallin S;
GN   Name=CRYGS; Synonyms=CRYG8;
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
//
ID   CRCM1_HUMAN             Reviewed;         301 AA.
AC   Q96D31; Q3MHV3; Q6DHX2; Q96BP7; Q96K71;
DE   RecName: Full=Calcium release-activated calcium channel protein 1;
DE   AltName: Full=Protein orai-1;
DE   AltName: Full=Transmembrane protein 142A;
GN   Name=ORAI1; Synonyms=CRACM1, TMEM142A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0002115; P:store-operated calcium entry; IEA:Ensembl.
//
ID   CRCM_HUMAN              Reviewed;         829 AA.
AC   P23508; D3DT05; Q6ZR04;
DE   RecName: Full=Colorectal mutant cancer protein;
DE            Short=Protein MCC;
GN   Name=MCC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CRCT1_HUMAN             Reviewed;          99 AA.
AC   Q9UGL9; A4QN00; Q6IAD7;
DE   RecName: Full=Cysteine-rich C-terminal protein 1;
DE   AltName: Full=Protein NICE-1;
GN   Name=CRCT1; Synonyms=C1orf42, NICE1;
//
ID   CRDL1_HUMAN             Reviewed;         450 AA.
AC   Q9BU40; B1AKD0; B4DMP3; D3DUY6; E9PGS5; Q539E4; Q9Y3H7;
DE   RecName: Full=Chordin-like protein 1;
DE   AltName: Full=Neuralin-1;
DE   AltName: Full=Neurogenesin-1;
DE   AltName: Full=Ventroptin;
DE   Flags: Precursor;
GN   Name=CHRDL1; Synonyms=NRLN1;
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048749; P:compound eye development; IMP:UniProtKB.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
//
ID   CRDL2_HUMAN             Reviewed;         429 AA.
AC   Q6WN34; A5PKU9; Q6WN30; Q6WN31; Q6WN32; Q7Z5J3;
DE   RecName: Full=Chordin-like protein 2;
DE   AltName: Full=Breast tumor novel factor 1;
DE            Short=BNF-1;
DE   AltName: Full=Chordin-related protein 2;
DE   Flags: Precursor;
GN   Name=CHRDL2; Synonyms=BNF1, CHL2; ORFNames=UNQ765/PRO1557;
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
//
ID   CREB1_HUMAN             Reviewed;         341 AA.
AC   P16220; P21934; Q6V963; Q9UMA7;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 1;
DE            Short=CREB-1;
DE            Short=cAMP-responsive element-binding protein 1;
GN   Name=CREB1;
DR   GO; GO:0035497; F:cAMP response element binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0060430; P:lung saccule development; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:MGI.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IDA:MGI.
DR   GO; GO:0033363; P:secretory granule organization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060509; P:Type I pneumocyte differentiation; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CREB3_HUMAN             Reviewed;         395 AA.
AC   O43889; D0PTW6; O14671; O14919; Q5TCV1; Q96GK8; Q9H2W3; Q9UE77;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 3;
DE            Short=CREB-3;
DE            Short=cAMP-responsive element-binding protein 3;
DE   AltName: Full=Leucine zipper protein;
DE   AltName: Full=Luman;
DE   AltName: Full=Transcription factor LZIP-alpha;
DE   Contains:
DE     RecName: Full=Processed cyclic AMP-responsive element-binding protein 3;
DE              Short=N-terminal Luman;
DE              Short=Transcriptionally active form;
GN   Name=CREB3; Synonyms=LZIP;
DR   GO; GO:0008140; F:cAMP response element binding protein binding; IDA:UniProtKB.
DR   GO; GO:0031726; F:CCR1 chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IDA:UniProtKB.
DR   GO; GO:0019043; P:establishment of viral latency; IDA:UniProtKB.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; NAS:UniProtKB.
DR   GO; GO:2000326; P:negative regulation of ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0090045; P:positive regulation of deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:UniProtKB.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006990; P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0019046; P:release from viral latency; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CREB5_HUMAN             Reviewed;         508 AA.
AC   Q02930; A8KA51; B4DU13; B5BUH3; C9JK47; Q05886; Q06246; Q75N02;
AC   Q86UJ9;
DE   RecName: Full=Cyclic AMP-responsive element-binding protein 5;
DE            Short=CREB-5;
DE            Short=cAMP-responsive element-binding protein 5;
DE   AltName: Full=CRE-BPa;
GN   Name=CREB5; Synonyms=CREBPA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CREG1_HUMAN             Reviewed;         220 AA.
AC   O75629; B2RDD4; Q8N9A3;
DE   RecName: Full=Protein CREG1;
DE   AltName: Full=Cellular repressor of E1A-stimulated genes 1;
DE   Flags: Precursor;
GN   Name=CREG1; Synonyms=CREG; ORFNames=UNQ727/PRO1409;
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CREG2_HUMAN             Reviewed;         290 AA.
AC   Q8IUH2; Q86X03; Q8N540; Q8N9E3;
DE   RecName: Full=Protein CREG2;
DE   Flags: Precursor;
GN   Name=CREG2;
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
//
ID   CREL1_HUMAN             Reviewed;         420 AA.
AC   Q96HD1; A8MX90; B2RAA9; Q6I9X5; Q8NFT4; Q9Y409;
DE   RecName: Full=Cysteine-rich with EGF-like domain protein 1;
DE   Flags: Precursor;
GN   Name=CRELD1; Synonyms=CIRRIN; ORFNames=UNQ188/PRO214;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003279; P:cardiac septum development; TAS:BHF-UCL.
DR   GO; GO:0003197; P:endocardial cushion development; TAS:BHF-UCL.
//
ID   CREL2_HUMAN             Reviewed;         353 AA.
AC   Q6UXH1; A5GZA2; A5GZA3; A5GZA4; A5GZA5; A5GZA6; Q4W0V0; Q86UC0;
AC   Q9BU47;
DE   RecName: Full=Cysteine-rich with EGF-like domain protein 2;
DE   Flags: Precursor;
GN   Name=CRELD2; ORFNames=UNQ185/PRO211;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CREM_HUMAN              Reviewed;         361 AA.
AC   Q03060; A8K014; A8K3J7; A8K6A1; A8MPQ2; B4DXC1; C9J785; C9JZ10;
AC   E9PAR4; E9PHM1; O75519; Q14501; Q14503; Q14504; Q14505; Q14506;
AC   Q15731; Q16114; Q16116; Q5T9H7; Q5W1A6; Q5W1A7; Q5W1A8; Q5W1A9;
AC   Q5W1B0; Q5W1B2; Q7Z2Q6; Q8IVD4; Q96AG7; Q9NZ98; Q9NZ99; Q9NZB9;
DE   RecName: Full=cAMP-responsive element modulator;
DE   AltName: Full=Inducible cAMP early repressor;
DE            Short=ICER;
GN   Name=CREM;
DR   GO; GO:0008140; F:cAMP response element binding protein binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CRERF_HUMAN             Reviewed;         639 AA.
AC   Q8IUR6; B3DFH2; B3KW49; D3DQM2; F5GXN3; Q5HYG4; Q5HYK0; Q86YR3;
AC   Q8IZG1;
DE   RecName: Full=CREB3 regulatory factor;
DE   AltName: Full=Luman recruitment factor;
DE            Short=LRF;
GN   Name=CREBRF; Synonyms=C5orf41;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1900102; P:negative regulation of endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032388; P:positive regulation of intracellular transport; IDA:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051222; P:positive regulation of protein transport; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   CREST_HUMAN             Reviewed;         396 AA.
AC   O75177; A6NNE3; A8K620; B3KWR8; E1P5H7; Q5JXJ3; Q6MZV9; Q6NTH3;
AC   Q6XYD9; Q8NE69; Q9BR55; Q9H4K6;
DE   RecName: Full=Calcium-responsive transactivator;
DE   AltName: Full=SS18-like protein 1;
DE   AltName: Full=SYT homolog 1;
GN   Name=SS18L1; Synonyms=CREST, KIAA0693;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0050773; P:regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CRFM7_HUMAN             Reviewed;         412 AA.
AC   Q494W8; A8KAB9;
DE   RecName: Full=CHRNA7-FAM7A fusion protein;
DE   AltName: Full=CHRNA7-DR1;
DE   AltName: Full=D-10;
GN   Name=CHRFAM7A;
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
//
ID   CRFR1_HUMAN             Reviewed;         444 AA.
AC   P34998; B4DIE9; Q13008; Q4QRJ1; Q9UK64;
DE   RecName: Full=Corticotropin-releasing factor receptor 1;
DE            Short=CRF-R-1;
DE            Short=CRF-R1;
DE            Short=CRFR-1;
DE   AltName: Full=Corticotropin-releasing hormone receptor 1;
DE            Short=CRH-R-1;
DE            Short=CRH-R1;
DE   Flags: Precursor;
GN   Name=CRHR1; Synonyms=CRFR, CRFR1, CRHR;
DR   GuidetoPHARMACOLOGY; 212; -.
DR   GO; GO:0015056; F:corticotrophin-releasing factor receptor activity; IDA:UniProtKB.
DR   GO; GO:0051424; F:corticotropin-releasing hormone binding; IEA:Ensembl.
DR   GO; GO:0043404; F:corticotropin-releasing hormone receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0048149; P:behavioral response to ethanol; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0071376; P:cellular response to corticotropin-releasing hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0051458; P:corticotropin secretion; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0042596; P:fear response; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; NAS:ProtInc.
DR   GO; GO:0051867; P:general adaptation syndrome, behavioral process; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0032811; P:negative regulation of epinephrine secretion; IEA:Ensembl.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:1901386; P:negative regulation of voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:Ensembl.
DR   GO; GO:0007567; P:parturition; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0010578; P:regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:2000852; P:regulation of corticosterone secretion; ISS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0035902; P:response to immobilization stress; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   CRFR2_HUMAN             Reviewed;         411 AA.
AC   Q13324; B2R967; B3SXS6; B3SXS7; B3SXS8; B3SXT0; F8WA81; O43461;
AC   Q4QRJ4; Q99431;
DE   RecName: Full=Corticotropin-releasing factor receptor 2;
DE            Short=CRF-R-2;
DE            Short=CRF-R2;
DE            Short=CRFR-2;
DE   AltName: Full=Corticotropin-releasing hormone receptor 2;
DE            Short=CRH-R-2;
DE            Short=CRH-R2;
GN   Name=CRHR2; Synonyms=CRF2R, CRH2R;
DR   GuidetoPHARMACOLOGY; 213; -.
DR   GO; GO:0015056; F:corticotrophin-releasing factor receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0043951; P:negative regulation of cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IEA:Ensembl.
//
ID   CRF_HUMAN               Reviewed;         196 AA.
AC   P06850; B3KQS4;
DE   RecName: Full=Corticoliberin;
DE   AltName: Full=Corticotropin-releasing factor;
DE            Short=CRF;
DE   AltName: Full=Corticotropin-releasing hormone;
DE   Flags: Precursor;
GN   Name=CRH;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0071314; P:cellular response to cocaine; IEA:Ensembl.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0016101; P:diterpenoid metabolic process; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IDA:UniProtKB.
DR   GO; GO:0033494; P:ferulate metabolic process; IEA:Ensembl.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008628; P:hormone-mediated apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0050801; P:ion homeostasis; IEA:Ensembl.
DR   GO; GO:0007611; P:learning or memory; TAS:ProtInc.
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0042322; P:negative regulation of circadian sleep/wake cycle, REM sleep; NAS:BHF-UCL.
DR   GO; GO:0032811; P:negative regulation of epinephrine secretion; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0070093; P:negative regulation of glucagon secretion; IEA:Ensembl.
DR   GO; GO:0033685; P:negative regulation of luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0007567; P:parturition; TAS:ProtInc.
DR   GO; GO:2000987; P:positive regulation of behavioral fear response; IEA:Ensembl.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010841; P:positive regulation of circadian sleep/wake cycle, wakefulness; NAS:BHF-UCL.
DR   GO; GO:2000854; P:positive regulation of corticosterone secretion; IEA:Ensembl.
DR   GO; GO:0051461; P:positive regulation of corticotropin secretion; IEA:Ensembl.
DR   GO; GO:0051464; P:positive regulation of cortisol secretion; IDA:BHF-UCL.
DR   GO; GO:0060456; P:positive regulation of digestive system process; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0014062; P:regulation of serotonin secretion; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0045472; P:response to ether; IEA:Ensembl.
DR   GO; GO:0035902; P:response to immobilization stress; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IDA:UniProtKB.
//
ID   CRGA_HUMAN              Reviewed;         174 AA.
AC   P11844; Q53ST5;
DE   RecName: Full=Gamma-crystallin A;
DE   AltName: Full=Gamma-A-crystallin;
DE   AltName: Full=Gamma-crystallin 5;
GN   Name=CRYGA; Synonyms=CRYG1;
DR   GO; GO:0005212; F:structural constituent of eye lens; NAS:UniProtKB.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; NAS:UniProtKB.
//
ID   CRGB_HUMAN              Reviewed;         175 AA.
AC   P07316; Q17RB5; Q53ST2;
DE   RecName: Full=Gamma-crystallin B;
DE   AltName: Full=Gamma-B-crystallin;
DE   AltName: Full=Gamma-crystallin 1-2;
GN   Name=CRYGB; Synonyms=CRYG2;
DR   GO; GO:0005212; F:structural constituent of eye lens; NAS:UniProtKB.
DR   GO; GO:0070309; P:lens fiber cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; NAS:UniProtKB.
//
ID   CRGC_HUMAN              Reviewed;         174 AA.
AC   P07315; Q53R50;
DE   RecName: Full=Gamma-crystallin C;
DE   AltName: Full=Gamma-C-crystallin;
DE   AltName: Full=Gamma-crystallin 2-1;
DE   AltName: Full=Gamma-crystallin 3;
GN   Name=CRYGC; Synonyms=CRYG3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; NAS:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CRGD_HUMAN              Reviewed;         174 AA.
AC   P07320; Q17RF7; Q53R51; Q99681;
DE   RecName: Full=Gamma-crystallin D;
DE   AltName: Full=Gamma-D-crystallin;
DE   AltName: Full=Gamma-crystallin 4;
GN   Name=CRYGD; Synonyms=CRYG4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; NAS:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0002088; P:lens development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0070306; P:lens fiber cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CRGN_HUMAN              Reviewed;         182 AA.
AC   Q8WXF5; Q496G6;
DE   RecName: Full=Gamma-crystallin N;
DE   AltName: Full=Gamma-N-crystallin;
GN   Name=CRYGN;
//
ID   CRHBP_HUMAN             Reviewed;         322 AA.
AC   P24387; Q53F32; Q6FHT5;
DE   RecName: Full=Corticotropin-releasing factor-binding protein;
DE            Short=CRF-BP;
DE            Short=CRF-binding protein;
DE   AltName: Full=Corticotropin-releasing hormone-binding protein;
DE            Short=CRH-BP;
DE   Flags: Precursor;
GN   Name=CRHBP; Synonyms=CRFBP;
DR   GO; GO:0051424; F:corticotropin-releasing hormone binding; IDA:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048149; P:behavioral response to ethanol; IMP:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.
DR   GO; GO:0071314; P:cellular response to cocaine; ISS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; ISS:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IDA:UniProtKB.
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.
DR   GO; GO:0097211; P:cellular response to gonadotropin-releasing hormone; ISS:UniProtKB.
DR   GO; GO:0035865; P:cellular response to potassium ion; IDA:UniProtKB.
DR   GO; GO:0033554; P:cellular response to stress; IMP:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IDA:UniProtKB.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0007611; P:learning or memory; TAS:UniProtKB.
DR   GO; GO:0002125; P:maternal aggressive behavior; IEA:Ensembl.
DR   GO; GO:0051460; P:negative regulation of corticotropin secretion; IDA:UniProtKB.
DR   GO; GO:1900011; P:negative regulation of corticotropin-releasing hormone receptor activity; IDA:UniProtKB.
DR   GO; GO:0045055; P:regulated secretory pathway; IDA:UniProtKB.
DR   GO; GO:0051459; P:regulation of corticotropin secretion; IDA:UniProtKB.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; ISS:UniProtKB.
//
ID   CRIM1_HUMAN             Reviewed;        1036 AA.
AC   Q9NZV1; Q2M2G4; Q59GH0; Q7LCQ5; Q9H318;
DE   RecName: Full=Cysteine-rich motor neuron 1 protein;
DE            Short=CRIM-1;
DE   AltName: Full=Cysteine-rich repeat-containing protein S52;
DE   Contains:
DE     RecName: Full=Processed cysteine-rich motor neuron 1 protein;
DE   Flags: Precursor;
GN   Name=CRIM1; Synonyms=S52; ORFNames=UNQ1886/PRO4330;
DR   GO; GO:0005010; F:insulin-like growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:MGI.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; TAS:GOC.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
//
ID   CRIP1_HUMAN             Reviewed;          77 AA.
AC   P50238; H3BPI2; Q13628; Q53XY7; Q96J34;
DE   RecName: Full=Cysteine-rich protein 1;
DE            Short=CRP-1;
DE   AltName: Full=Cysteine-rich heart protein;
DE            Short=CRHP;
DE            Short=hCRHP;
DE   AltName: Full=Cysteine-rich intestinal protein;
DE            Short=CRIP;
GN   Name=CRIP1; Synonyms=CRIP, CRP1;
DR   GO; GO:0003680; F:AT DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0071236; P:cellular response to antibiotic; IDA:UniProtKB.
DR   GO; GO:0071493; P:cellular response to UV-B; IDA:UniProtKB.
DR   GO; GO:0007507; P:heart development; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEP:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0060741; P:prostate gland stromal morphogenesis; IEP:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IEP:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IEP:UniProtKB.
DR   GO; GO:0010043; P:response to zinc ion; IDA:UniProtKB.
//
ID   CRIP2_HUMAN             Reviewed;         208 AA.
AC   P52943; A1A4U1; B7Z6C0; E9PD13;
DE   RecName: Full=Cysteine-rich protein 2;
DE            Short=CRP-2;
DE   AltName: Full=Protein ESP1;
GN   Name=CRIP2; Synonyms=CRP2;
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   CRIP3_HUMAN             Reviewed;         217 AA.
AC   Q6Q6R5; A2A436; Q5T043; Q6Q6R4; Q6Q6R6; Q6Q6R7;
DE   RecName: Full=Cysteine-rich protein 3;
DE            Short=CRP-3;
DE   AltName: Full=Chromosome 6 LIM domain only protein;
DE            Short=h6LIMo;
GN   Name=CRIP3; Synonyms=CRP3;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
//
ID   CRIPT_HUMAN             Reviewed;         101 AA.
AC   Q9P021;
DE   RecName: Full=Cysteine-rich PDZ-binding protein;
DE   AltName: Full=Cysteine-rich interactor of PDZ three;
DE            Short=Cysteine-rich interactor of PDZ3;
GN   Name=CRIPT; ORFNames=HSPC139;
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProt.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; ISS:UniProt.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; ISS:UniProt.
DR   GO; GO:0045184; P:establishment of protein localization; ISS:UniProt.
DR   GO; GO:0035372; P:protein localization to microtubule; ISS:UniProt.
DR   GO; GO:1902897; P:regulation of postsynaptic density protein 95 clustering; ISS:UniProt.
//
ID   CRIS1_HUMAN             Reviewed;         249 AA.
AC   P54107; B5BU98; O00698; Q13248; Q14082; Q96SF6;
DE   RecName: Full=Cysteine-rich secretory protein 1;
DE            Short=CRISP-1;
DE   AltName: Full=AEG-like protein;
DE   AltName: Full=ARP;
DE   AltName: Full=Acidic epididymal glycoprotein homolog;
DE   Flags: Precursor;
GN   Name=CRISP1; Synonyms=AEGL1;
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; TAS:ProtInc.
//
ID   CRIS2_HUMAN             Reviewed;         243 AA.
AC   P16562; A8K8M0; Q53FF2; Q5U8Z9; Q7Z7B2;
DE   RecName: Full=Cysteine-rich secretory protein 2;
DE            Short=CRISP-2;
DE   AltName: Full=Cancer/testis antigen 36;
DE            Short=CT36;
DE   AltName: Full=Testis-specific protein TPX-1;
DE   Flags: Precursor;
GN   Name=CRISP2; Synonyms=GAPDL5, TPX1;
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
//
ID   CRIS3_HUMAN             Reviewed;         245 AA.
AC   P54108; A8K9S1; B2R8I8; Q15512; Q3MJ82; Q53FA9; Q5JW83; Q9H108;
DE   RecName: Full=Cysteine-rich secretory protein 3;
DE            Short=CRISP-3;
DE   AltName: Full=Specific granule protein of 28 kDa;
DE            Short=SGP28;
DE   Flags: Precursor;
GN   Name=CRISP3;
DR   GO; GO:0006952; P:defense response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
//
ID   CRIT1_HUMAN             Reviewed;         157 AA.
AC   Q96LR1; C9JG53;
DE   RecName: Full=Putative uncharacterized protein encoded by CRHR1-IT1;
DE   AltName: Full=CRHR1 intronic transcript 1;
DE   Flags: Precursor;
GN   Name=CRHR1-IT1; Synonyms=C17orf69;
//
ID   CRKL_HUMAN              Reviewed;         303 AA.
AC   P46109; A8KA44; D3DX35;
DE   RecName: Full=Crk-like protein;
GN   Name=CRKL;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0060017; P:parathyroid gland development; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   CRK_HUMAN               Reviewed;         304 AA.
AC   P46108; A8MWE8; B0LPE8; D3DTH6; Q96GA9; Q96HJ0;
DE   RecName: Full=Adapter molecule crk;
DE   AltName: Full=Proto-oncogene c-Crk;
DE   AltName: Full=p38;
GN   Name=CRK;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IEA:GOC.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0035020; P:regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   CRLD1_HUMAN             Reviewed;         500 AA.
AC   Q9H336; B2RA60;
DE   RecName: Full=Cysteine-rich secretory protein LCCL domain-containing 1;
DE   AltName: Full=CocoaCrisp;
DE   AltName: Full=Cysteine-rich secretory protein 10;
DE            Short=CRISP-10;
DE   AltName: Full=LCCL domain-containing cysteine-rich secretory protein 1;
DE   AltName: Full=Trypsin inhibitor Hl;
DE   Flags: Precursor;
GN   Name=CRISPLD1; Synonyms=CRISP10, LCRISP1; ORFNames=UNQ342/PRO541;
DR   GO; GO:0060325; P:face morphogenesis; IMP:UniProt.
//
ID   CRLD2_HUMAN             Reviewed;         497 AA.
AC   Q9H0B8; D3DUM0; Q6P590; Q6UWH0; Q6UXC6; Q96IB1; Q96K61;
DE   RecName: Full=Cysteine-rich secretory protein LCCL domain-containing 2;
DE   AltName: Full=Cysteine-rich secretory protein 11;
DE            Short=CRISP-11;
DE   AltName: Full=LCCL domain-containing cysteine-rich secretory protein 2;
DE   Flags: Precursor;
GN   Name=CRISPLD2; Synonyms=CRISP11, LCRISP2;
GN   ORFNames=UNQ2914/PRO1156/PRO9783;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IMP:UniProt.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
//
ID   CRLF1_HUMAN             Reviewed;         422 AA.
AC   O75462; Q9UHH5;
DE   RecName: Full=Cytokine receptor-like factor 1;
DE   AltName: Full=Cytokine-like factor 1;
DE            Short=CLF-1;
DE   AltName: Full=ZcytoR5;
DE   Flags: Precursor;
GN   Name=CRLF1; ORFNames=UNQ288/PRO327;
DR   GO; GO:0019955; F:cytokine binding; IPI:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:2000672; P:negative regulation of motor neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   CRLF2_HUMAN             Reviewed;         371 AA.
AC   Q9HC73; Q9H5R3;
DE   RecName: Full=Cytokine receptor-like factor 2;
DE   AltName: Full=Cytokine receptor-like 2;
DE   AltName: Full=IL-XR;
DE   AltName: Full=Thymic stromal lymphopoietin protein receptor;
DE            Short=TSLP receptor;
DE   Flags: Precursor;
GN   Name=CRLF2; Synonyms=CRL2, ILXR, TSLPR;
//
ID   CRLF3_HUMAN             Reviewed;         442 AA.
AC   Q8IUI8; A6NJF3; B2R8C3; Q2MLY7; Q9UNI3; Q9Y6M8;
DE   RecName: Full=Cytokine receptor-like factor 3;
DE   AltName: Full=Cytokine receptor-like molecule 9;
DE            Short=CREME-9;
DE   AltName: Full=Cytokine receptor-related protein 4;
DE   AltName: Full=Type I cytokine receptor-like factor p48;
GN   Name=CRLF3; Synonyms=CREME9, CRLM9, CYTOR4, P48;
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   CRLS1_HUMAN             Reviewed;         301 AA.
AC   Q9UJA2; D3DW09; E9PAT4; Q27RP0; Q69YQ5;
DE   RecName: Full=Cardiolipin synthase;
DE            Short=CLS;
DE            EC=2.7.8.-;
DE   AltName: Full=Protein GCD10 homolog;
GN   Name=CRLS1; Synonyms=C20orf155, CLS1;
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CRML_HUMAN              Reviewed;        1269 AA.
AC   Q96RY5; A8MZL1; B1AJY1; Q8NDN1; Q9P2C1;
DE   RecName: Full=Protein cramped-like;
DE   AltName: Full=Hematological and neurological expressed 1-like protein;
GN   Name=CRAMP1L; Synonyms=C16orf34, HN1L, KIAA1426;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   CRNL1_HUMAN             Reviewed;         848 AA.
AC   Q9BZJ0; A8K9T4; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ1; Q9BZJ2; Q9GZW7;
AC   Q9H8F8; Q9NQH5; Q9NYD8;
DE   RecName: Full=Crooked neck-like protein 1;
DE   AltName: Full=Crooked neck homolog;
DE            Short=hCrn;
GN   Name=CRNKL1; Synonyms=CRN; ORFNames=CGI-201, MSTP021;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
//
ID   CRNN_HUMAN              Reviewed;         495 AA.
AC   Q9UBG3; B2RE60; Q8N613;
DE   RecName: Full=Cornulin;
DE   AltName: Full=53 kDa putative calcium-binding protein;
DE   AltName: Full=53 kDa squamous epithelial-induced stress protein;
DE   AltName: Full=58 kDa heat shock protein;
DE   AltName: Full=Squamous epithelial heat shock protein 53;
DE   AltName: Full=Tumor-related protein;
GN   Name=CRNN; Synonyms=C1orf10, DRC1, PDRC1, SEP53;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0009408; P:response to heat; IDA:UniProtKB.
//
ID   CRNS1_HUMAN             Reviewed;         827 AA.
AC   A5YM72; A8K1M3; B4DFC6; E9PK38; F5H427; Q8N467; Q9P2F3;
DE   RecName: Full=Carnosine synthase 1;
DE            EC=6.3.2.11;
DE   AltName: Full=ATP-grasp domain-containing protein 1;
GN   Name=CARNS1; Synonyms=ATPGD1, KIAA1394;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:MGI.
DR   GO; GO:0047730; F:carnosine synthase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0035499; P:carnosine biosynthetic process; IDA:UniProtKB.
//
ID   CROC4_HUMAN             Reviewed;         156 AA.
AC   Q13536; B1ALL5; B1ALL8;
DE   RecName: Full=Protein CROC-4;
DE   AltName: Full=Contingent replication of cDNA 4;
GN   Name=C1orf61; Synonyms=CROC4;
//
ID   CROCC_HUMAN             Reviewed;        2017 AA.
AC   Q5TZA2; Q2VHY3; Q66GT7; Q7Z2L4; Q7Z5D7;
DE   RecName: Full=Rootletin;
DE   AltName: Full=Ciliary rootlet coiled-coil protein;
GN   Name=CROCC; Synonyms=KIAA0445;
DR   GO; GO:0019894; F:kinesin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0051297; P:centrosome organization; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
//
ID   CROL2_HUMAN             Reviewed;         287 AA.
AC   Q8IVE0; Q96PW6;
DE   RecName: Full=Putative ciliary rootlet coiled-coil protein-like 2 protein;
DE   AltName: Full=Ciliary rootlet coiled-coil protein pseudogene 3;
GN   Name=CROCCP3; Synonyms=CROCCL2, KIAA1922;
//
ID   CROL1_HUMAN             Reviewed;         111 AA.
AC   Q86T23; Q8NF65; Q96FR5; Q9BRE8;
DE   RecName: Full=Putative ciliary rootlet coiled-coil protein-like 1 protein;
DE   AltName: Full=Ciliary rootlet coiled-coil protein pseudogene 2;
GN   Name=CROCCP2; Synonyms=CROCCL1;
//
ID   CROL3_HUMAN             Reviewed;        2252 AA.
AC   H7BZ55;
DE   RecName: Full=Putative ciliary rootlet coiled-coil protein-like 3 protein;
//
ID   CRPAK_HUMAN             Reviewed;         446 AA.
AC   Q8N1N5; Q8NB03;
DE   RecName: Full=Cysteine-rich PAK1 inhibitor;
DE            Short=CRIPak;
GN   Name=CRIPAK;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:HGNC.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; IDA:HGNC.
DR   GO; GO:0043627; P:response to estrogen; IDA:HGNC.
//
ID   CRP_HUMAN               Reviewed;         224 AA.
AC   P02741; A8K078; D3DVD9; D3DVE0; Q08AK3; Q8WW75;
DE   RecName: Full=C-reactive protein;
DE   Contains:
DE     RecName: Full=C-reactive protein(1-205);
DE   Flags: Precursor;
GN   Name=CRP; Synonyms=PTX1;
DR   GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR   GO; GO:0033265; F:choline binding; TAS:BHF-UCL.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006953; P:acute-phase response; TAS:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; TAS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0010888; P:negative regulation of lipid storage; IDA:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0008228; P:opsonization; TAS:BHF-UCL.
DR   GO; GO:1900006; P:positive regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:0051258; P:protein polymerization; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   CRSPL_HUMAN             Reviewed;         253 AA.
AC   Q9H3Y0;
DE   RecName: Full=Peptidase inhibitor R3HDML;
DE   AltName: Full=Cysteine-rich secretory protein R3HDML;
DE   Flags: Precursor;
GN   Name=R3HDML;
DR   GO; GO:0030414; F:peptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   CRTAM_HUMAN             Reviewed;         393 AA.
AC   O95727; Q59EI1; Q6IRX2;
DE   RecName: Full=Cytotoxic and regulatory T-cell molecule;
DE   AltName: Full=Class-I MHC-restricted T-cell-associated molecule;
DE   AltName: CD_antigen=CD355;
DE   Flags: Precursor;
GN   Name=CRTAM;
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0008037; P:cell recognition; IDA:HGNC.
DR   GO; GO:0051606; P:detection of stimulus; IDA:HGNC.
DR   GO; GO:0002355; P:detection of tumor cell; IDA:HGNC.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:HGNC.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IDA:HGNC.
DR   GO; GO:0002860; P:positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; IDA:HGNC.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   CRTAP_HUMAN             Reviewed;         401 AA.
AC   O75718; B2RBL6;
DE   RecName: Full=Cartilage-associated protein;
DE   Flags: Precursor;
GN   Name=CRTAP; Synonyms=CASP;
DR   GO; GO:0032403; F:protein complex binding; ISS:UniProt.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; ISS:UniProt.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:1901874; P:negative regulation of post-translational protein modification; IMP:UniProt.
DR   GO; GO:0018400; P:peptidyl-proline hydroxylation to 3-hydroxy-L-proline; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CRTC1_HUMAN             Reviewed;         634 AA.
AC   Q6UUV9; A6NMG5; O75114; Q6Y3A3; Q7LDZ2; Q8IUL3; Q8IZ34; Q8IZL1;
AC   Q8N6W3; Q96AI8; Q9H801;
DE   RecName: Full=CREB-regulated transcription coactivator 1;
DE   AltName: Full=Mucoepidermoid carcinoma translocated protein 1;
DE   AltName: Full=Transducer of regulated cAMP response element-binding protein 1;
DE            Short=TORC-1;
DE            Short=Transducer of CREB protein 1;
GN   Name=CRTC1; Synonyms=KIAA0616, MECT1, TORC1, WAMTP1;
DR   GO; GO:0008140; F:cAMP response element binding protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CRTC2_HUMAN             Reviewed;         693 AA.
AC   Q53ET0; Q6UUV8; Q7Z3X7; Q8N332;
DE   RecName: Full=CREB-regulated transcription coactivator 2;
DE   AltName: Full=Transducer of regulated cAMP response element-binding protein 2;
DE            Short=TORC-2;
DE            Short=Transducer of CREB protein 2;
GN   Name=CRTC2; Synonyms=TORC2;
DR   GO; GO:0008140; F:cAMP response element binding protein binding; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CRTC3_HUMAN             Reviewed;         619 AA.
AC   Q6UUV7; Q6DK61; Q6DK62; Q8NF38; Q9H6U2;
DE   RecName: Full=CREB-regulated transcription coactivator 3;
DE   AltName: Full=Transducer of regulated cAMP response element-binding protein 3;
DE            Short=TORC-3;
DE            Short=Transducer of CREB protein 3;
GN   Name=CRTC3; Synonyms=TORC3;
DR   GO; GO:0008140; F:cAMP response element binding protein binding; IEA:InterPro.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IEA:InterPro.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CRUM1_HUMAN             Reviewed;        1406 AA.
AC   P82279; A2A308; B7Z5T2; B9EG71; Q5K3A6; Q5TC28; Q5VUT1; Q6N027;
AC   Q8WWY0; Q8WWY1;
DE   RecName: Full=Protein crumbs homolog 1;
DE   Flags: Precursor;
GN   Name=CRB1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:Ensembl.
//
ID   CRUM2_HUMAN             Reviewed;        1285 AA.
AC   Q5IJ48; A2A3N4; Q0QD46; Q5JS41; Q5JS43; Q6ZTA9; Q6ZWI6;
DE   RecName: Full=Protein crumbs homolog 2;
DE   AltName: Full=Crumbs-like protein 2;
DE   Flags: Precursor;
GN   Name=CRB2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0072358; P:cardiovascular system development; ISS:UniProt.
DR   GO; GO:0045199; P:maintenance of epithelial cell apical/basal polarity; ISS:UniProt.
DR   GO; GO:0001707; P:mesoderm formation; ISS:UniProt.
DR   GO; GO:0014028; P:notochord formation; ISS:UniProt.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProt.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:UniProt.
DR   GO; GO:0001756; P:somitogenesis; ISS:UniProt.
//
ID   CRUM3_HUMAN             Reviewed;         120 AA.
AC   Q9BUF7; A8KA91; D6W643; Q8N0V8; Q8WVA0;
DE   RecName: Full=Protein crumbs homolog 3;
DE   Flags: Precursor;
GN   Name=CRB3; ORFNames=UNQ588/PRO1158;
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   CRX_HUMAN               Reviewed;         299 AA.
AC   O43186; Q0QD45;
DE   RecName: Full=Cone-rod homeobox protein;
GN   Name=CRX; Synonyms=CORD2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0046534; P:positive regulation of photoreceptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CRY1_HUMAN              Reviewed;         586 AA.
AC   Q16526;
DE   RecName: Full=Cryptochrome-1;
GN   Name=CRY1; Synonyms=PHLL1;
DR   GO; GO:0009882; F:blue light photoreceptor activity; NAS:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003913; F:DNA photolyase activity; IEA:InterPro.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0009785; P:blue light signaling pathway; NAS:UniProtKB.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0042754; P:negative regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CRY2_HUMAN              Reviewed;         593 AA.
AC   Q49AN0; B4DH32; O75148; Q8IV71;
DE   RecName: Full=Cryptochrome-2;
GN   Name=CRY2; Synonyms=KIAA0658;
DR   GO; GO:0009882; F:blue light photoreceptor activity; NAS:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003913; F:DNA photolyase activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; ISS:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0009785; P:blue light signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0042754; P:negative regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0032515; P:negative regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:2000118; P:regulation of sodium-dependent phosphate transport; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CRYAA_HUMAN             Reviewed;         173 AA.
AC   P02489; Q53X53;
DE   RecName: Full=Alpha-crystallin A chain;
DE   AltName: Full=Heat shock protein beta-4;
DE            Short=HspB4;
DE   Contains:
DE     RecName: Full=Alpha-crystallin A(1-172);
DE   Contains:
DE     RecName: Full=Alpha-crystallin A(1-168);
DE   Contains:
DE     RecName: Full=Alpha-crystallin A(1-162);
GN   Name=CRYAA; Synonyms=CRYA1, HSPB4;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IMP:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0070309; P:lens fiber cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032387; P:negative regulation of intracellular transport; IDA:HGNC.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0070141; P:response to UV-A; IEA:Ensembl.
DR   GO; GO:0007021; P:tubulin complex assembly; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   CRYAB_HUMAN             Reviewed;         175 AA.
AC   P02511; B0YIX0; O43416; Q9UC37; Q9UC38; Q9UC39; Q9UC40; Q9UC41;
DE   RecName: Full=Alpha-crystallin B chain;
DE   AltName: Full=Alpha(B)-crystallin;
DE   AltName: Full=Heat shock protein beta-5;
DE            Short=HspB5;
DE   AltName: Full=Renal carcinoma antigen NY-REN-27;
DE   AltName: Full=Rosenthal fiber component;
GN   Name=CRYAB; Synonyms=CRYA2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IMP:MGI.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0031109; P:microtubule polymerization or depolymerization; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:HGNC.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032387; P:negative regulation of intracellular transport; IDA:HGNC.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; NAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0010941; P:regulation of cell death; IMP:MGI.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; IEA:Ensembl.
DR   GO; GO:0007021; P:tubulin complex assembly; IEA:Ensembl.
//
ID   CRYL1_HUMAN             Reviewed;         319 AA.
AC   Q9Y2S2; A0PJ43; B3KN92; Q0VDI1; Q7Z4Z9; Q9P0G7;
DE   RecName: Full=Lambda-crystallin homolog;
DE            EC=1.1.1.45;
DE   AltName: Full=L-gulonate 3-dehydrogenase;
DE            Short=Gul3DH;
GN   Name=CRYL1; Synonyms=CRY;
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0050104; F:L-gulonate 3-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0070403; F:NAD+ binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
//
ID   CRYM_HUMAN              Reviewed;         314 AA.
AC   Q14894; D5MNX0; Q5HYB7;
DE   RecName: Full=Ketimine reductase mu-crystallin;
DE            EC=1.5.1.25;
DE   AltName: Full=NADP-regulated thyroid-hormone-binding protein;
GN   Name=CRYM; Synonyms=THBP;
DR   GO; GO:0050661; F:NADP binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0047127; F:thiomorpholine-carboxylate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070324; F:thyroid hormone binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0042403; P:thyroid hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0070327; P:thyroid hormone transport; IMP:UniProtKB.
//
ID   CS010_HUMAN             Reviewed;         173 AA.
AC   Q969H8; D6W628; O75256; O75272; Q9BTK7; Q9NP69;
DE   RecName: Full=UPF0556 protein C19orf10;
DE   AltName: Full=Interleukin-25;
DE            Short=IL-25;
DE   AltName: Full=Stromal cell-derived growth factor SF20;
DE   Flags: Precursor;
GN   Name=C19orf10; Synonyms=IL25;
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
//
ID   CS012_HUMAN             Reviewed;         152 AA.
AC   Q9NSK7; B3KQ16; Q0D2Q0; Q6P4C5; Q9BSL7;
DE   RecName: Full=Protein C19orf12;
GN   Name=C19orf12;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   CS018_HUMAN             Reviewed;         215 AA.
AC   Q8NEA5;
DE   RecName: Full=Uncharacterized protein C19orf18;
DE   Flags: Precursor;
GN   Name=C19orf18;
//
ID   CS024_HUMAN             Reviewed;         132 AA.
AC   Q9BVV8; Q9NWS2;
DE   RecName: Full=Uncharacterized membrane protein C19orf24;
DE   Flags: Precursor;
GN   Name=C19orf24;
//
ID   CS025_HUMAN             Reviewed;         118 AA.
AC   Q9UFG5; B3KQN6; Q8N9R7; Q8WV94;
DE   RecName: Full=UPF0449 protein C19orf25;
GN   Name=C19orf25;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CS035_HUMAN             Reviewed;         473 AA.
AC   Q6ZS72;
DE   RecName: Full=Putative uncharacterized protein C19orf35;
GN   Name=C19orf35;
//
ID   CS043_HUMAN             Reviewed;         176 AA.
AC   Q9BQ61;
DE   RecName: Full=Uncharacterized protein C19orf43;
GN   Name=C19orf43;
//
ID   CS044_HUMAN             Reviewed;         657 AA.
AC   Q9H6X5; Q8N6Y7;
DE   RecName: Full=Uncharacterized protein C19orf44;
GN   Name=C19orf44;
//
ID   CS047_HUMAN             Reviewed;         422 AA.
AC   Q8N9M1; Q8IZ33; Q8N0V9;
DE   RecName: Full=Uncharacterized protein C19orf47;
GN   Name=C19orf47;
//
ID   CS045_HUMAN             Reviewed;         505 AA.
AC   Q8NA69; Q8N115;
DE   RecName: Full=Uncharacterized protein C19orf45;
GN   Name=C19orf45;
//
ID   CS052_HUMAN             Reviewed;         260 AA.
AC   Q9BSF4; Q96EY6; Q96IT8;
DE   RecName: Full=Uncharacterized protein C19orf52;
GN   Name=C19orf52;
//
ID   CS048_HUMAN             Reviewed;         117 AA.
AC   Q6RUI8;
DE   RecName: Full=Uncharacterized protein C19orf48;
DE   AltName: Full=Multidrug resistance-related protein;
GN   Name=C19orf48;
//
ID   CS055_HUMAN             Reviewed;         480 AA.
AC   Q2NL68; Q8NDI3; Q8WWC8; Q96NL4;
DE   RecName: Full=Uncharacterized protein C19orf55;
GN   Name=C19orf55;
//
ID   CS054_HUMAN             Reviewed;         351 AA.
AC   Q5BKX5; A8MSZ5; B4DNU7;
DE   RecName: Full=UPF0692 protein C19orf54;
GN   Name=C19orf54;
//
ID   CS057_HUMAN             Reviewed;         668 AA.
AC   Q0VDD7; Q13411; Q8N825; Q96D63; Q9BU49;
DE   RecName: Full=Uncharacterized protein C19orf57;
DE   AltName: Full=Pre-T/NK cell-associated protein 3B3;
GN   Name=C19orf57;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
//
ID   CS060_HUMAN             Reviewed;         201 AA.
AC   Q96EN9; E9PAS0; Q8NAX4; Q9NWI0;
DE   RecName: Full=Uncharacterized protein C19orf60;
GN   Name=C19orf60;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CS066_HUMAN             Reviewed;         291 AA.
AC   Q9NUL5; A8MQT9; Q4G188; Q8IYH6; Q8N8V1;
DE   RecName: Full=UPF0515 protein C19orf66;
GN   Name=C19orf66;
//
ID   CS067_HUMAN             Reviewed;         358 AA.
AC   A6NJJ6;
DE   RecName: Full=UPF0575 protein C19orf67;
GN   Name=C19orf67;
//
ID   CS068_HUMAN             Reviewed;         627 AA.
AC   Q86XI8;
DE   RecName: Full=Uncharacterized protein C19orf68;
GN   Name=C19orf68;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   CS071_HUMAN             Reviewed;         209 AA.
AC   A6NCJ1;
DE   RecName: Full=Uncharacterized protein C19orf71;
GN   Name=C19orf71;
//
ID   CS073_HUMAN             Reviewed;         129 AA.
AC   Q9NVV2; Q6NSX4;
DE   RecName: Full=Putative uncharacterized protein C19orf73;
GN   Name=C19orf73;
//
ID   CS081_HUMAN             Reviewed;         198 AA.
AC   C9J6K1;
DE   RecName: Full=Putative uncharacterized protein C19orf81;
GN   Name=C19orf81;
//
ID   CS082_HUMAN             Reviewed;         104 AA.
AC   K7EIQ3;
DE   RecName: Full=Uncharacterized protein C19orf82;
GN   Name=C19orf82;
//
ID   CS083_HUMAN             Reviewed;         104 AA.
AC   K7EIZ4;
DE   RecName: Full=Putative uncharacterized protein C19orf83;
GN   Name=C19orf83;
//
ID   CS084_HUMAN             Reviewed;         186 AA.
AC   I3L1E1;
DE   RecName: Full=Uncharacterized protein C19orf84;
GN   Name=C19orf84;
//
ID   CSAD_HUMAN              Reviewed;         493 AA.
AC   Q9Y600; A8K0U4; Q4QQH9; Q9UNJ5; Q9Y601;
DE   RecName: Full=Cysteine sulfinic acid decarboxylase;
DE            EC=4.1.1.29;
DE   AltName: Full=Cysteine-sulfinate decarboxylase;
DE   AltName: Full=Sulfinoalanine decarboxylase;
GN   Name=CSAD; Synonyms=CSD;
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0004782; F:sulfinoalanine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0042412; P:taurine biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   CSAS1_HUMAN             Reviewed;         109 AA.
AC   Q8TBR5;
DE   RecName: Full=Putative uncharacterized protein CIRBP-AS1;
DE   AltName: Full=CIRBP antisense RNA 1;
DE   AltName: Full=CIRBP antisense gene protein 1;
GN   Name=CIRBP-AS1; Synonyms=C19orf23;
//
ID   CSAG1_HUMAN             Reviewed;          78 AA.
AC   Q6PB30; A6NE22;
DE   RecName: Full=Putative chondrosarcoma-associated gene 1 protein;
DE   AltName: Full=Cancer/testis antigen 24.1;
DE            Short=CT24.1;
DE   AltName: Full=Cancer/testis antigen CSAGE;
DE   Flags: Precursor;
GN   Name=CSAG1; Synonyms=CSAGE;
//
ID   CSAG2_HUMAN             Reviewed;         127 AA.
AC   Q9Y5P2; O75605; Q0VDC3; Q96IU8;
DE   RecName: Full=Chondrosarcoma-associated gene 2/3 protein;
DE   AltName: Full=Cancer/testis antigen 24.2;
DE            Short=CT24.2;
DE   AltName: Full=Taxol-resistant-associated gene 3 protein;
DE            Short=TRAG-3;
GN   Name=CSAG2; Synonyms=TRAG3;
GN   and
GN   Name=CSAG3; Synonyms=CSAG3A;
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
//
ID   CSC10_HUMAN             Reviewed;         136 AA.
AC   Q5T4H9; A1L4M3;
DE   RecName: Full=Protein CASC10;
DE   AltName: Full=Cancer susceptibility candidate gene 10 protein;
GN   Name=CASC10; Synonyms=C10orf114;
//
ID   CSC2A_HUMAN             Reviewed;         102 AA.
AC   Q6XLA1; D3DRC5;
DE   RecName: Full=Protein CASC2, isoform 3;
DE   AltName: Full=Cancer susceptibility candidate gene 2 protein, isoform 3;
GN   Name=CASC2; Synonyms=C10orf5;
//
ID   CSDC2_HUMAN             Reviewed;         153 AA.
AC   Q9Y534; Q8ND37;
DE   RecName: Full=Cold shock domain-containing protein C2;
DE   AltName: Full=RNA-binding protein PIPPin;
GN   Name=CSDC2; Synonyms=PIPPIN;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   CSDE1_HUMAN             Reviewed;         798 AA.
AC   O75534; A8K281; E9PGZ0; G5E9Q2; O94961; Q5TF04; Q5TF05; Q68DF1;
AC   Q68DI9; Q9Y2S4;
DE   RecName: Full=Cold shock domain-containing protein E1;
DE   AltName: Full=N-ras upstream gene protein;
DE   AltName: Full=Protein UNR;
GN   Name=CSDE1; Synonyms=D1S155E, KIAA0885, NRU, UNR;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0070966; P:nuclear-transcribed mRNA catabolic process, no-go decay; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   CSEN_HUMAN              Reviewed;         256 AA.
AC   Q9Y2W7; H7BY46; Q3YAC3; Q3YAC4; Q53TJ5; Q96T40; Q9UJ84; Q9UJ85;
DE   RecName: Full=Calsenilin;
DE   AltName: Full=A-type potassium channel modulatory protein 3;
DE   AltName: Full=DRE-antagonist modulator;
DE            Short=DREAM;
DE   AltName: Full=Kv channel-interacting protein 3;
DE            Short=KChIP3;
GN   Name=KCNIP3; Synonyms=CSEN, DREAM, KCHIP3;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CSF1R_HUMAN             Reviewed;         972 AA.
AC   P07333; B5A955; D3DQG2; Q6LDW5; Q6LDY4; Q86VW7;
DE   RecName: Full=Macrophage colony-stimulating factor 1 receptor;
DE   AltName: Full=CSF-1 receptor;
DE            Short=CSF-1-R;
DE            Short=CSF-1R;
DE            Short=M-CSF-R;
DE            EC=2.7.10.1;
DE   AltName: Full=Proto-oncogene c-Fms;
DE   AltName: CD_antigen=CD115;
DE   Flags: Precursor;
GN   Name=CSF1R; Synonyms=FMS;
DR   GuidetoPHARMACOLOGY; 1806; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019955; F:cytokine binding; IDA:UniProtKB.
DR   GO; GO:0005011; F:macrophage colony-stimulating factor receptor activity; IMP:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045217; P:cell-cell junction maintenance; IMP:UniProtKB.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.
DR   GO; GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IMP:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IMP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0038145; P:macrophage colony-stimulating factor signaling pathway; IMP:GOC.
DR   GO; GO:0030225; P:macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0060603; P:mammary gland duct morphogenesis; TAS:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:2000147; P:positive regulation of cell motility; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IMP:UniProtKB.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0045124; P:regulation of bone resorption; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0031529; P:ruffle organization; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB.
//
ID   CSF1_HUMAN              Reviewed;         554 AA.
AC   P09603; A8K6J5; Q13130; Q14086; Q14806; Q5VVF3; Q5VVF4; Q9UQR8;
DE   RecName: Full=Macrophage colony-stimulating factor 1;
DE            Short=CSF-1;
DE            Short=M-CSF;
DE            Short=MCSF;
DE   AltName: Full=Lanimostim;
DE   Contains:
DE     RecName: Full=Processed macrophage colony-stimulating factor 1;
DE   Flags: Precursor;
GN   Name=CSF1;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0005157; F:macrophage colony-stimulating factor receptor binding; TAS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0003006; P:developmental process involved in reproduction; ISS:BHF-UCL.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0030225; P:macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0060763; P:mammary duct terminal end bud growth; IEA:Ensembl.
DR   GO; GO:0060611; P:mammary gland fat development; IEA:Ensembl.
DR   GO; GO:0042117; P:monocyte activation; NAS:BHF-UCL.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0002158; P:osteoclast proliferation; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IDA:BHF-UCL.
DR   GO; GO:0045657; P:positive regulation of monocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0032946; P:positive regulation of mononuclear cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0042488; P:positive regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0010743; P:regulation of macrophage derived foam cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0030278; P:regulation of ossification; IEA:Ensembl.
//
ID   CSF2R_HUMAN             Reviewed;         400 AA.
AC   P15509; A7J003; A8KAM1; B4DW68; J3JS76; J3JS77; O00207; Q14429;
AC   Q14430; Q14431; Q16564;
DE   RecName: Full=Granulocyte-macrophage colony-stimulating factor receptor subunit alpha;
DE            Short=GM-CSF-R-alpha;
DE            Short=GMCSFR-alpha;
DE            Short=GMR-alpha;
DE   AltName: Full=CDw116;
DE   AltName: CD_antigen=CD116;
DE   Flags: Precursor;
GN   Name=CSF2RA; Synonyms=CSF2R, CSF2RY;
DR   GuidetoPHARMACOLOGY; 1707; -.
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
//
ID   CSF2_HUMAN              Reviewed;         144 AA.
AC   P04141; Q14CE8; Q2VPI8; Q8NFI6;
DE   RecName: Full=Granulocyte-macrophage colony-stimulating factor;
DE            Short=GM-CSF;
DE   AltName: Full=Colony-stimulating factor;
DE            Short=CSF;
DE   AltName: Full=Molgramostin;
DE   AltName: Full=Sargramostim;
DE   Flags: Precursor;
GN   Name=CSF2; Synonyms=GMCSF;
DR   GO; GO:0005129; F:granulocyte macrophage colony-stimulating factor receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0097028; P:dendritic cell differentiation; IDA:DFLAT.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0042045; P:epithelial fluid transport; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0042116; P:macrophage activation; IEA:Ensembl.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0045918; P:negative regulation of cytolysis; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0032747; P:positive regulation of interleukin-23 production; IDA:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0071803; P:positive regulation of podosome assembly; IDA:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
//
ID   CSF3R_HUMAN             Reviewed;         836 AA.
AC   Q99062;
DE   RecName: Full=Granulocyte colony-stimulating factor receptor;
DE            Short=G-CSF receptor;
DE            Short=G-CSF-R;
DE   AltName: CD_antigen=CD114;
DE   Flags: Precursor;
GN   Name=CSF3R; Synonyms=GCSFR;
DR   GuidetoPHARMACOLOGY; 1719; -.
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CSF3_HUMAN              Reviewed;         207 AA.
AC   P09919; A8MXR7;
DE   RecName: Full=Granulocyte colony-stimulating factor;
DE            Short=G-CSF;
DE   AltName: Full=Pluripoietin;
DE   AltName: INN=Filgrastim;
DE   AltName: INN=Lenograstim;
DE   Flags: Precursor;
GN   Name=CSF3; Synonyms=C17orf33, GCSF;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005130; F:granulocyte colony-stimulating factor receptor binding; TAS:ProtInc.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IDA:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0030851; P:granulocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   CSHL_HUMAN              Reviewed;         222 AA.
AC   Q14406; D3DU26; D3DU27; Q0VDB2;
DE   RecName: Full=Chorionic somatomammotropin hormone-like 1;
DE            Short=Chorionic somatomammotropin-like;
DE   AltName: Full=Lactogen-like;
DE   Flags: Precursor;
GN   Name=CSHL1; Synonyms=CSHP1, CSL;
DR   GO; GO:0005179; F:hormone activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   CSH_HUMAN               Reviewed;         217 AA.
AC   P01243; Q0VDB1; Q14407;
DE   RecName: Full=Chorionic somatomammotropin hormone;
DE            Short=Choriomammotropin;
DE   AltName: Full=Lactogen;
DE   AltName: Full=Placental lactogen;
DE            Short=PL;
DE   Flags: Precursor;
GN   Name=CSH1;
GN   and
GN   Name=CSH2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   CSK21_HUMAN             Reviewed;         391 AA.
AC   P68400; B4DYS6; D3DVV8; P19138; P20426; Q14013; Q5U065;
DE   RecName: Full=Casein kinase II subunit alpha;
DE            Short=CK II alpha;
DE            EC=2.7.11.1;
GN   Name=CSNK2A1; Synonyms=CK2A1;
DR   GuidetoPHARMACOLOGY; 1549; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051879; F:Hsp90 protein binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071174; P:mitotic spindle checkpoint; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CSK22_HUMAN             Reviewed;         350 AA.
AC   P19784;
DE   RecName: Full=Casein kinase II subunit alpha';
DE            Short=CK II alpha';
DE            EC=2.7.11.1;
GN   Name=CSNK2A2; Synonyms=CK2A2;
DR   GuidetoPHARMACOLOGY; 1550; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071174; P:mitotic spindle checkpoint; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CSK23_HUMAN             Reviewed;         391 AA.
AC   Q8NEV1;
DE   RecName: Full=Casein kinase II subunit alpha 3;
DE            Short=CK II alpha 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Casein kinase II alpha 1 polypeptide pseudogene;
GN   Name=CSNK2A3; Synonyms=CSNK2A1P;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   CSK2B_HUMAN             Reviewed;         215 AA.
AC   P67870; B0UXA9; P07312; P13862; Q4VX47;
DE   RecName: Full=Casein kinase II subunit beta;
DE            Short=CK II beta;
DE   AltName: Full=Phosvitin;
DE   AltName: Full=Protein G5a;
GN   Name=CSNK2B; Synonyms=CK2N, G5A;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0019887; F:protein kinase regulator activity; NAS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0033211; P:adiponectin-activated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0043623; P:cellular protein complex assembly; NAS:BHF-UCL.
DR   GO; GO:0061154; P:endothelial tube morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0032927; P:positive regulation of activin receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:GOC.
DR   GO; GO:0051101; P:regulation of DNA binding; NAS:BHF-UCL.
DR   GO; GO:0045859; P:regulation of protein kinase activity; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CSKI1_HUMAN             Reviewed;        1431 AA.
AC   Q8WXD9; Q9P2P0;
DE   RecName: Full=Caskin-1;
DE   AltName: Full=CASK-interacting protein 1;
GN   Name=CASKIN1; Synonyms=KIAA1306;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
//
ID   CSKI2_HUMAN             Reviewed;        1202 AA.
AC   Q8WXE0; B4DTT3; B7Z9H1; Q7LG69; Q9ULT1;
DE   RecName: Full=Caskin-2;
DE   AltName: Full=CASK-interacting protein 2;
GN   Name=CASKIN2; Synonyms=KIAA1139;
//
ID   CSKP_HUMAN              Reviewed;         926 AA.
AC   O14936; A6NES1; B7ZKY0; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17;
AC   Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3;
DE   RecName: Full=Peripheral plasma membrane protein CASK;
DE            Short=hCASK;
DE            EC=2.7.11.1;
DE   AltName: Full=Calcium/calmodulin-dependent serine protein kinase;
DE   AltName: Full=Protein lin-2 homolog;
GN   Name=CASK; Synonyms=LIN2;
DR   GuidetoPHARMACOLOGY; 1959; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0070509; P:calcium ion import; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0090288; P:negative regulation of cellular response to growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:BHF-UCL.
DR   GO; GO:0061045; P:negative regulation of wound healing; IMP:BHF-UCL.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   CSK_HUMAN               Reviewed;         450 AA.
AC   P41240; Q2M3N2; Q6FGZ6;
DE   RecName: Full=Tyrosine-protein kinase CSK;
DE            EC=2.7.10.2;
DE   AltName: Full=C-Src kinase;
DE   AltName: Full=Protein-tyrosine kinase CYL;
GN   Name=CSK;
DR   GuidetoPHARMACOLOGY; 1994; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0034332; P:adherens junction organization; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; IDA:UniProtKB.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IEA:Ensembl.
DR   GO; GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IEA:Ensembl.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0060368; P:regulation of Fc receptor mediated stimulatory signaling pathway; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   CSMD1_HUMAN             Reviewed;        3565 AA.
AC   Q96PZ7; Q0H0J5; Q96QU9; Q96RM4;
DE   RecName: Full=CUB and sushi domain-containing protein 1;
DE   AltName: Full=CUB and sushi multiple domains protein 1;
DE   Flags: Precursor;
GN   Name=CSMD1; Synonyms=KIAA1890; ORFNames=UNQ5952/PRO19863;
//
ID   CSMT1_HUMAN             Reviewed;         132 AA.
AC   Q4G0I0; Q96RZ0;
DE   RecName: Full=Protein CCSMST1;
DE   Flags: Precursor;
GN   Name=CCSMST1; Synonyms=C16orf91;
//
ID   CSMD2_HUMAN             Reviewed;        3487 AA.
AC   Q7Z408; B1AM50; Q5VT59; Q8N963; Q96Q03; Q9H4V7; Q9H4V8; Q9H4V9;
AC   Q9H4W0; Q9H4W1; Q9H4W2; Q9H4W3; Q9H4W4; Q9HCY5; Q9HCY6; Q9HCY7;
DE   RecName: Full=CUB and sushi domain-containing protein 2;
DE   AltName: Full=CUB and sushi multiple domains protein 2;
GN   Name=CSMD2; Synonyms=KIAA1884;
//
ID   CSMD3_HUMAN             Reviewed;        3707 AA.
AC   Q7Z407; Q96PZ3;
DE   RecName: Full=CUB and sushi domain-containing protein 3;
DE   AltName: Full=CUB and sushi multiple domains protein 3;
GN   Name=CSMD3; Synonyms=KIAA1894;
//
ID   CSN1_HUMAN              Reviewed;         491 AA.
AC   Q13098; Q8NA10; Q9BWL1;
DE   RecName: Full=COP9 signalosome complex subunit 1;
DE            Short=SGN1;
DE            Short=Signalosome subunit 1;
DE   AltName: Full=G protein pathway suppressor 1;
DE            Short=GPS-1;
DE   AltName: Full=JAB1-containing signalosome subunit 1;
DE   AltName: Full=Protein MFH;
GN   Name=GPS1; Synonyms=COPS1, CSN1;
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
//
ID   CSN2_HUMAN              Reviewed;         443 AA.
AC   P61201; O88950; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5;
DE   RecName: Full=COP9 signalosome complex subunit 2;
DE            Short=SGN2;
DE            Short=Signalosome subunit 2;
DE   AltName: Full=Alien homolog;
DE   AltName: Full=JAB1-containing signalosome subunit 2;
DE   AltName: Full=Thyroid receptor-interacting protein 15;
DE            Short=TR-interacting protein 15;
DE            Short=TRIP-15;
GN   Name=COPS2; Synonyms=CSN2, TRIP15;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.
//
ID   CSN3_HUMAN              Reviewed;         423 AA.
AC   Q9UNS2; B2R683; B4DY81; O43191; Q7LDR6;
DE   RecName: Full=COP9 signalosome complex subunit 3;
DE            Short=SGN3;
DE            Short=Signalosome subunit 3;
DE   AltName: Full=JAB1-containing signalosome subunit 3;
GN   Name=COPS3; Synonyms=CSN3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CSN4_HUMAN              Reviewed;         406 AA.
AC   Q9BT78; B3KN88; B3KST5; Q561W7; Q9NW31; Q9Y677;
DE   RecName: Full=COP9 signalosome complex subunit 4;
DE            Short=SGN4;
DE            Short=Signalosome subunit 4;
DE   AltName: Full=JAB1-containing signalosome subunit 4;
GN   Name=COPS4; Synonyms=CSN4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:0000338; P:protein deneddylation; IMP:UniProtKB.
//
ID   CSN5_HUMAN              Reviewed;         334 AA.
AC   Q92905; O15386; Q6AW95; Q86WQ4; Q9BQ17;
DE   RecName: Full=COP9 signalosome complex subunit 5;
DE            Short=SGN5;
DE            Short=Signalosome subunit 5;
DE            EC=3.4.-.-;
DE   AltName: Full=Jun activation domain-binding protein 1;
GN   Name=COPS5; Synonyms=CSN5, JAB1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; TAS:ProtInc.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:1990182; P:exosomal secretion; IDA:FlyBase.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000338; P:protein deneddylation; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0006413; P:translational initiation; TAS:GOC.
//
ID   CSN6_HUMAN              Reviewed;         327 AA.
AC   Q7L5N1; A4D2A3; O15387;
DE   RecName: Full=COP9 signalosome complex subunit 6;
DE            Short=SGN6;
DE            Short=Signalosome subunit 6;
DE   AltName: Full=JAB1-containing signalosome subunit 6;
DE   AltName: Full=MOV34 homolog;
DE   AltName: Full=Vpr-interacting protein;
DE            Short=hVIP;
GN   Name=COPS6; Synonyms=CSN6, HVIP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CSN7A_HUMAN             Reviewed;         275 AA.
AC   Q9UBW8; A8K9A6; Q9NVX3; Q9UJW4;
DE   RecName: Full=COP9 signalosome complex subunit 7a;
DE            Short=SGN7a;
DE            Short=Signalosome subunit 7a;
DE   AltName: Full=Dermal papilla-derived protein 10;
DE   AltName: Full=JAB1-containing signalosome subunit 7a;
GN   Name=COPS7A; Synonyms=CSN7A, DERP10;
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
//
ID   CSN7B_HUMAN             Reviewed;         264 AA.
AC   Q9H9Q2; Q53S22; Q5BJG3; Q9H7V6;
DE   RecName: Full=COP9 signalosome complex subunit 7b;
DE            Short=SGN7b;
DE            Short=Signalosome subunit 7b;
DE   AltName: Full=JAB1-containing signalosome subunit 7b;
GN   Name=COPS7B; Synonyms=CSN7B;
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
//
ID   CSN8_HUMAN              Reviewed;         209 AA.
AC   Q99627; A8K1H6; Q53QS9;
DE   RecName: Full=COP9 signalosome complex subunit 8;
DE            Short=SGN8;
DE            Short=Signalosome subunit 8;
DE   AltName: Full=COP9 homolog;
DE            Short=hCOP9;
DE   AltName: Full=JAB1-containing signalosome subunit 8;
GN   Name=COPS8; Synonyms=CSN8;
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProt.
DR   GO; GO:0010388; P:cullin deneddylation; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProt.
//
ID   CSPG2_HUMAN             Reviewed;        3396 AA.
AC   P13611; P20754; Q13010; Q13189; Q15123; Q9UCL9; Q9UNW5;
DE   RecName: Full=Versican core protein;
DE   AltName: Full=Chondroitin sulfate proteoglycan core protein 2;
DE            Short=Chondroitin sulfate proteoglycan 2;
DE   AltName: Full=Glial hyaluronate-binding protein;
DE            Short=GHAP;
DE   AltName: Full=Large fibroblast proteoglycan;
DE   AltName: Full=PG-M;
DE   Flags: Precursor;
GN   Name=VCAN; Synonyms=CSPG2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005539; F:glycosaminoglycan binding; TAS:ProtInc.
DR   GO; GO:0005540; F:hyaluronic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0008037; P:cell recognition; TAS:ProtInc.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008347; P:glial cell migration; IDA:BHF-UCL.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CSPG4_HUMAN             Reviewed;        2322 AA.
AC   Q6UVK1; D3DW77; Q92675;
DE   RecName: Full=Chondroitin sulfate proteoglycan 4;
DE   AltName: Full=Chondroitin sulfate proteoglycan NG2;
DE   AltName: Full=Melanoma chondroitin sulfate proteoglycan;
DE   AltName: Full=Melanoma-associated chondroitin sulfate proteoglycan;
DE   Flags: Precursor;
GN   Name=CSPG4; Synonyms=MCSP;
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048771; P:tissue remodeling; IEA:UniProtKB-KW.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   CSPG5_HUMAN             Reviewed;         566 AA.
AC   O95196; Q71M39; Q71M40;
DE   RecName: Full=Chondroitin sulfate proteoglycan 5;
DE   AltName: Full=Acidic leucine-rich EGF-like domain-containing brain protein;
DE   AltName: Full=Neuroglycan C;
DE   Flags: Precursor;
GN   Name=CSPG5; Synonyms=CALEB, NGC;
DR   GO; GO:0008083; F:growth factor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0046907; P:intracellular transport; TAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0050804; P:regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CSPP1_HUMAN             Reviewed;        1256 AA.
AC   Q1MSJ5; A6ND63; Q70F00; Q8TBC1;
DE   RecName: Full=Centrosome and spindle pole-associated protein 1;
GN   Name=CSPP1; Synonyms=CSPP;
DR   GO; GO:0051781; P:positive regulation of cell division; IMP:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
//
ID   CSR2B_HUMAN             Reviewed;         782 AA.
AC   Q9H8E8; A2A2I5; Q96GW6; Q96IH3; Q9HBF0; Q9UIY5;
DE   RecName: Full=Cysteine-rich protein 2-binding protein;
DE            Short=CSRP2-binding protein;
DE   AltName: Full=ADA2A-containing complex subunit 2;
DE            Short=ATAC2;
DE   AltName: Full=CRP2-binding partner;
DE            Short=CRP2BP;
GN   Name=CSRP2BP;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:MGI.
DR   GO; GO:0030274; F:LIM domain binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
//
ID   CSRN1_HUMAN             Reviewed;         589 AA.
AC   Q96S65; Q69YY5;
DE   RecName: Full=Cysteine/serine-rich nuclear protein 1;
DE            Short=CSRNP-1;
DE   AltName: Full=Axin-1 up-regulated gene 1 protein;
DE   AltName: Full=Protein URAX1;
DE   AltName: Full=TGF-beta-induced apoptosis protein 3;
DE            Short=TAIP-3;
GN   Name=CSRNP1; Synonyms=AXUD1, TAIP3;
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
//
ID   CSRN2_HUMAN             Reviewed;         543 AA.
AC   Q9H175;
DE   RecName: Full=Cysteine/serine-rich nuclear protein 2;
DE            Short=CSRNP-2;
DE   AltName: Full=Protein FAM130A1;
DE   AltName: Full=TGF-beta-induced apoptosis protein 12;
DE            Short=TAIP-12;
GN   Name=CSRNP2; Synonyms=C12orf22, FAM130A1, TAIP12;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   CSRN3_HUMAN             Reviewed;         585 AA.
AC   Q8WYN3; B3KPR4; Q53SG0; Q6ZTX3; Q9HAF9;
DE   RecName: Full=Cysteine/serine-rich nuclear protein 3;
DE            Short=CSRNP-3;
DE   AltName: Full=Protein FAM130A2;
DE   AltName: Full=TGF-beta-induced apoptosis protein 2;
DE            Short=TAIP-2;
GN   Name=CSRNP3; Synonyms=FAM130A2, TAIP2;
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   CSRP1_HUMAN             Reviewed;         193 AA.
AC   P21291; A8K268; Q5U0J2;
DE   RecName: Full=Cysteine and glycine-rich protein 1;
DE   AltName: Full=Cysteine-rich protein 1;
DE            Short=CRP;
DE            Short=CRP1;
DE   AltName: Full=Epididymis luminal protein 141;
DE            Short=HEL-141;
GN   Name=CSRP1; Synonyms=CSRP, CYRP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
//
ID   CSRP2_HUMAN             Reviewed;         193 AA.
AC   Q16527; Q93030;
DE   RecName: Full=Cysteine and glycine-rich protein 2;
DE   AltName: Full=Cysteine-rich protein 2;
DE            Short=CRP2;
DE   AltName: Full=LIM domain only protein 5;
DE            Short=LMO-5;
DE   AltName: Full=Smooth muscle cell LIM protein;
DE            Short=SmLIM;
GN   Name=CSRP2; Synonyms=LMO5, SMLIM;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   CSRP3_HUMAN             Reviewed;         194 AA.
AC   P50461; Q9P131;
DE   RecName: Full=Cysteine and glycine-rich protein 3;
DE   AltName: Full=Cardiac LIM protein;
DE   AltName: Full=Cysteine-rich protein 3;
DE            Short=CRP3;
DE   AltName: Full=LIM domain protein, cardiac;
DE   AltName: Full=Muscle LIM protein;
GN   Name=CSRP3; Synonyms=CLP, MLP;
DR   GO; GO:0042805; F:actinin binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:BHF-UCL.
DR   GO; GO:0031433; F:telethonin binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0003300; P:cardiac muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:0048738; P:cardiac muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0035995; P:detection of muscle stretch; IMP:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; IMP:BHF-UCL.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:ProtInc.
//
ID   CST11_HUMAN             Reviewed;         138 AA.
AC   Q9H112; Q0VAF2; Q0VAF3; Q8WXU5; Q8WXU6; Q9H113;
DE   RecName: Full=Cystatin-11;
DE   Flags: Precursor;
GN   Name=CST11; Synonyms=CST8L;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   CST1L_HUMAN             Reviewed;         145 AA.
AC   Q9H114; Q17RA8; Q64FF7;
DE   RecName: Full=Cystatin-like 1;
DE   AltName: Full=RCET11;
DE   Flags: Precursor;
GN   Name=CSTL1;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   CST8_HUMAN              Reviewed;         142 AA.
AC   O60676; Q2M2X6;
DE   RecName: Full=Cystatin-8;
DE   AltName: Full=Cystatin-related epididymal spermatogenic protein;
DE   Flags: Precursor;
GN   Name=CST8; Synonyms=CRES;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   CST9L_HUMAN             Reviewed;         147 AA.
AC   Q9H4G1; B2R5A1;
DE   RecName: Full=Cystatin-9-like;
DE   Flags: Precursor;
GN   Name=CST9L; ORFNames=UNQ1835/PRO3543;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   CST9P_HUMAN             Reviewed;         147 AA.
AC   Q5W188;
DE   RecName: Full=Putative cystatin-9-like protein CST9LP1;
DE   AltName: Full=Cystatin-9-like pseudogene 1;
DE   Flags: Precursor;
GN   Name=CST9LP1;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   CST9_HUMAN              Reviewed;         159 AA.
AC   Q5W186; B2RP76; Q8TD53;
DE   RecName: Full=Cystatin-9;
DE   AltName: Full=Cystatin-like molecule;
DE   Flags: Precursor;
GN   Name=CST9; Synonyms=CLM;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   CSTF1_HUMAN             Reviewed;         431 AA.
AC   Q05048; Q5QPD8;
DE   RecName: Full=Cleavage stimulation factor subunit 1;
DE   AltName: Full=CF-1 50 kDa subunit;
DE   AltName: Full=Cleavage stimulation factor 50 kDa subunit;
DE            Short=CSTF 50 kDa subunit;
DE            Short=CstF-50;
GN   Name=CSTF1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; TAS:ProtInc.
DR   GO; GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CSTF2_HUMAN             Reviewed;         577 AA.
AC   P33240; Q5H951; Q6LA74; Q8N502;
DE   RecName: Full=Cleavage stimulation factor subunit 2;
DE   AltName: Full=CF-1 64 kDa subunit;
DE   AltName: Full=Cleavage stimulation factor 64 kDa subunit;
DE            Short=CSTF 64 kDa subunit;
DE            Short=CstF-64;
GN   Name=CSTF2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; TAS:ProtInc.
DR   GO; GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CSTF3_HUMAN             Reviewed;         717 AA.
AC   Q12996; A8K471; D3DR04; E9PB40; Q32P22; Q96FQ8; Q96QD6; Q96QK4;
DE   RecName: Full=Cleavage stimulation factor subunit 3;
DE   AltName: Full=CF-1 77 kDa subunit;
DE   AltName: Full=Cleavage stimulation factor 77 kDa subunit;
DE            Short=CSTF 77 kDa subunit;
DE            Short=CstF-77;
GN   Name=CSTF3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; TAS:ProtInc.
DR   GO; GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   CSTFT_HUMAN             Reviewed;         616 AA.
AC   Q9H0L4; B2RAR9; O75174; Q53HK6; Q7LGE8; Q8N6T1;
DE   RecName: Full=Cleavage stimulation factor subunit 2 tau variant;
DE   AltName: Full=CF-1 64 kDa subunit tau variant;
DE   AltName: Full=Cleavage stimulation factor 64 kDa subunit tau variant;
DE            Short=CSTF 64 kDa subunit tau variant;
DE   AltName: Full=TauCstF-64;
GN   Name=CSTF2T; Synonyms=KIAA0689;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   CSTN1_HUMAN             Reviewed;         981 AA.
AC   O94985; A8K183; Q5SR52; Q5UE58; Q71MN0; Q8N4K9;
DE   RecName: Full=Calsyntenin-1;
DE   AltName: Full=Alcadein-alpha;
DE            Short=Alc-alpha;
DE   AltName: Full=Alzheimer-related cadherin-like protein;
DE   AltName: Full=Non-classical cadherin XB31alpha;
DE   Contains:
DE     RecName: Full=Soluble Alc-alpha;
DE              Short=SAlc-alpha;
DE   Contains:
DE     RecName: Full=CTF1-alpha;
DE     AltName: Full=C-terminal fragment 1-alpha;
DE   Flags: Precursor;
GN   Name=CLSTN1; Synonyms=CS1, KIAA0911;
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042988; F:X11-like protein binding; IPI:UniProt.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProt.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CSTN2_HUMAN             Reviewed;         955 AA.
AC   Q9H4D0; B2RCW5; D3DNF4; Q3SX54; Q3ZB76; Q5UE56; Q96HZ2; Q9BSS0;
DE   RecName: Full=Calsyntenin-2;
DE   AltName: Full=Alcadein-gamma;
DE            Short=Alc-gamma;
DE   Flags: Precursor;
GN   Name=CLSTN2; Synonyms=CS2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CSTN3_HUMAN             Reviewed;         956 AA.
AC   Q9BQT9; D3DUT6; O94831; Q2T9J5; Q5UE57;
DE   RecName: Full=Calsyntenin-3;
DE   AltName: Full=Alcadein-beta;
DE            Short=Alc-beta;
DE   Flags: Precursor;
GN   Name=CLSTN3; Synonyms=CS3, KIAA0726;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   CT024_HUMAN             Reviewed;         137 AA.
AC   Q9BUV8; E1P5U0; O00605; Q5QPG6; Q5QPG7; Q9BT03; Q9BZU7; Q9UI05;
DE   RecName: Full=Uncharacterized protein C20orf24;
DE   AltName: Full=Rab5-interacting protein;
DE            Short=RIP5;
GN   Name=C20orf24; ORFNames=PNAS-11;
//
ID   CT026_HUMAN             Reviewed;        1237 AA.
AC   Q8NHU2; A6NHA1; Q5JXV4; Q5TE18; Q8N5R9; Q96M59; Q9BQL2; Q9H127;
AC   Q9H128; Q9NQH4; Q9UFV8; Q9Y4V7;
DE   RecName: Full=Uncharacterized protein C20orf26;
GN   Name=C20orf26;
//
ID   CT027_HUMAN             Reviewed;         174 AA.
AC   Q9GZN8; A8K4J0; D3DVX8; Q5JX81; Q9NWX3;
DE   RecName: Full=UPF0687 protein C20orf27;
GN   Name=C20orf27;
//
ID   CT062_HUMAN             Reviewed;         170 AA.
AC   Q4KN68; A2A2S9; Q5QPC4;
DE   RecName: Full=Uncharacterized protein C20orf62;
GN   Name=C20orf62;
//
ID   CT085_HUMAN             Reviewed;         137 AA.
AC   Q9H1P6;
DE   RecName: Full=Uncharacterized protein C20orf85;
GN   Name=C20orf85;
//
ID   CT078_HUMAN             Reviewed;         151 AA.
AC   Q9BR46;
DE   RecName: Full=Putative uncharacterized protein C20orf78;
GN   Name=C20orf78;
//
ID   CT096_HUMAN             Reviewed;         363 AA.
AC   Q9NUD7; A3KPE0; B2RPH9; Q8N840; Q8NAX5;
DE   RecName: Full=Uncharacterized protein C20orf96;
GN   Name=C20orf96;
//
ID   CT112_HUMAN             Reviewed;         436 AA.
AC   Q96MY1; Q5JYB7; Q6P0Y4; Q9BR34; Q9NQF6;
DE   RecName: Full=Uncharacterized protein C20orf112;
GN   Name=C20orf112; Synonyms=C20orf113;
//
ID   CT141_HUMAN             Reviewed;         165 AA.
AC   Q9NUB4;
DE   RecName: Full=Uncharacterized protein C20orf141;
GN   Name=C20orf141;
//
ID   CT144_HUMAN             Reviewed;         153 AA.
AC   Q9BQM9; Q1AHR2;
DE   RecName: Full=Uncharacterized protein C20orf144;
DE   AltName: Full=Bcl-2-like protein from testis;
DE            Short=Bclt;
GN   Name=C20orf144;
//
ID   CT166_HUMAN             Reviewed;         117 AA.
AC   Q9H1L0; Q2TB30;
DE   RecName: Full=Uncharacterized protein C20orf166;
GN   Name=C20orf166;
//
ID   CT173_HUMAN             Reviewed;         149 AA.
AC   Q96LM9; A6PVJ1; Q2M293; Q5JWS4; Q9H449;
DE   RecName: Full=Uncharacterized protein C20orf173;
GN   Name=C20orf173;
//
ID   CT187_HUMAN             Reviewed;          50 AA.
AC   Q9UGB4;
DE   RecName: Full=Putative uncharacterized protein C20orf187;
GN   Name=C20orf187;
//
ID   CT18_HUMAN              Reviewed;          33 AA.
AC   P0C5K6;
DE   RecName: Full=Putative tumor antigen NA88-A;
DE   AltName: Full=Cancer/testis antigen 18;
DE            Short=CT18;
GN   Name=VENTXP1;
//
ID   CT191_HUMAN             Reviewed;         102 AA.
AC   Q9H4R4; A2RUA0;
DE   RecName: Full=Putative nuclear receptor corepressor 1-like protein NCOR1P1;
DE   AltName: Full=Nuclear receptor corepressor 1 pseudogene 1;
GN   Name=NCOR1P1; Synonyms=C20orf191;
//
ID   CT194_HUMAN             Reviewed;        1177 AA.
AC   Q5TEA3; Q66K86; Q6P2R9; Q9UFX9;
DE   RecName: Full=Uncharacterized protein C20orf194;
GN   Name=C20orf194;
//
ID   CT195_HUMAN             Reviewed;         318 AA.
AC   Q9BVV2;
DE   RecName: Full=Uncharacterized protein C20orf195;
GN   Name=C20orf195;
//
ID   CT196_HUMAN             Reviewed;         205 AA.
AC   Q8IYI0; A8K9J3; Q5TGA9; Q96LU1;
DE   RecName: Full=Uncharacterized protein C20orf196;
GN   Name=C20orf196;
//
ID   CT197_HUMAN             Reviewed;         126 AA.
AC   Q8N268; Q08EQ0;
DE   RecName: Full=Uncharacterized protein C20orf197;
GN   Name=C20orf197;
//
ID   CT202_HUMAN             Reviewed;         122 AA.
AC   A1L168;
DE   RecName: Full=Uncharacterized protein C20orf202;
GN   Name=C20orf202;
//
ID   CT203_HUMAN             Reviewed;         194 AA.
AC   Q8NBC4; B8JHY2;
DE   RecName: Full=Uncharacterized protein C20orf203;
GN   Name=C20orf203;
//
ID   CT2NL_HUMAN             Reviewed;         639 AA.
AC   Q9P2B4; B3KMS5; Q96B40;
DE   RecName: Full=CTTNBP2 N-terminal-like protein;
GN   Name=CTTNBP2NL; Synonyms=KIAA1433;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CT451_HUMAN             Reviewed;         189 AA.
AC   Q5HYN5; B9EIR8;
DE   RecName: Full=Cancer/testis antigen family 45 member A1;
DE   AltName: Full=Cancer/testis antigen 45-1;
DE   AltName: Full=Cancer/testis antigen 45A1;
GN   Name=CT45A1; Synonyms=CT45-1;
//
ID   CT452_HUMAN             Reviewed;         189 AA.
AC   Q5DJT8; Q5JRH3;
DE   RecName: Full=Cancer/testis antigen family 45 member A2;
DE   AltName: Full=Cancer/testis antigen 45-2;
DE   AltName: Full=Cancer/testis antigen 45A2;
GN   Name=CT45A2; Synonyms=CT45-2;
//
ID   CT453_HUMAN             Reviewed;         189 AA.
AC   Q8NHU0; B2RU20; B7ZMC9; D3DTG6;
DE   RecName: Full=Cancer/testis antigen family 45 member A3;
DE   AltName: Full=Cancer/testis antigen 45-3;
DE   AltName: Full=Cancer/testis antigen 45A3;
GN   Name=CT45A3; Synonyms=CT45-3;
//
ID   CT454_HUMAN             Reviewed;         189 AA.
AC   Q8N7B7;
DE   RecName: Full=Cancer/testis antigen family 45 member A4/A6;
DE   AltName: Full=Cancer/testis antigen 45-4/6;
DE   AltName: Full=Cancer/testis antigen 45A4/45A6;
GN   Name=CT45A4; Synonyms=CT45-4;
GN   and
GN   Name=CT45A6; Synonyms=CT45-6;
//
ID   CT455_HUMAN             Reviewed;         189 AA.
AC   Q6NSH3; A8K842; B7ZMC5;
DE   RecName: Full=Cancer/testis antigen family 45 member A5;
DE   AltName: Full=Cancer/testis antigen 45-5;
DE   AltName: Full=Cancer/testis antigen 45A5;
GN   Name=CT45A5; Synonyms=CT45-5;
//
ID   CT47A_HUMAN             Reviewed;         288 AA.
AC   Q5JQC4; Q8N747;
DE   RecName: Full=Cancer/testis antigen 47A;
DE   AltName: Full=Cancer/testis antigen 47;
DE            Short=CT47;
GN   Name=CT47A1; Synonyms=CT47.1;
GN   and
GN   Name=CT47A2; Synonyms=CT47.2;
GN   and
GN   Name=CT47A3; Synonyms=CT47.3;
GN   and
GN   Name=CT47A4; Synonyms=CT47.4;
GN   and
GN   Name=CT47A5; Synonyms=CT47.5;
GN   and
GN   Name=CT47A6; Synonyms=CT47.6;
GN   and
GN   Name=CT47A7; Synonyms=CT47.7;
GN   and
GN   Name=CT47A8; Synonyms=CT47.8;
GN   and
GN   Name=CT47A9; Synonyms=CT47.9;
GN   and
GN   Name=CT47A10; Synonyms=CT47.10;
GN   and
GN   Name=CT47A11; Synonyms=CT47.11;
GN   and
GN   Name=CT47A12; Synonyms=CT47.12;
//
ID   CT47B_HUMAN             Reviewed;         299 AA.
AC   P0C2W7; A6NM97;
DE   RecName: Full=Cancer/testis antigen 47B;
DE   AltName: Full=Cancer/testis antigen 47.13;
DE            Short=CT47.13;
GN   Name=CT47B1; Synonyms=CT47.13;
//
ID   CT55_HUMAN              Reviewed;         264 AA.
AC   Q8WUE5; Q9NWY8;
DE   RecName: Full=Cancer/testis antigen 55;
DE   AltName: Full=Tumor antigen BJ-HCC-20;
GN   Name=CT55; Synonyms=CXorf48;
//
ID   CT62_HUMAN              Reviewed;         136 AA.
AC   P0C5K7;
DE   RecName: Full=Cancer/testis antigen 62;
DE            Short=CT62;
GN   Name=CT62;
//
ID   CTAG2_HUMAN             Reviewed;         210 AA.
AC   O75638; O75637; Q0VIL6; Q14CD6; Q2Z1N4; Q9BU80; Q9UJ89; Q9Y479;
DE   RecName: Full=Cancer/testis antigen 2;
DE            Short=CT2;
DE   AltName: Full=Autoimmunogenic cancer/testis antigen NY-ESO-2;
DE   AltName: Full=Cancer/testis antigen 6.2;
DE            Short=CT6.2;
DE   AltName: Full=L antigen family member 1;
DE            Short=LAGE-1;
GN   Name=CTAG2; Synonyms=ESO2, LAGE1;
//
ID   CTBL1_HUMAN             Reviewed;         563 AA.
AC   Q8WYA6; Q0VAL9; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454;
AC   Q8NCL2; Q8TBD6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7;
DE   RecName: Full=Beta-catenin-like protein 1;
DE   AltName: Full=Nuclear-associated protein;
DE            Short=NAP;
DE   AltName: Full=Testis development protein NYD-SP19;
GN   Name=CTNNBL1; Synonyms=C20orf33; ORFNames=PP8304;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0016445; P:somatic diversification of immunoglobulins; IMP:UniProtKB.
//
ID   CTBP1_HUMAN             Reviewed;         440 AA.
AC   Q13363; Q4W5N3; Q7Z2Q5;
DE   RecName: Full=C-terminal-binding protein 1;
DE            Short=CtBP1;
DE            EC=1.1.1.-;
GN   Name=CTBP1; Synonyms=CTBP;
DR   GO; GO:0051287; F:NAD binding; ISS:UniProtKB.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IMP:BHF-UCL.
DR   GO; GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.
DR   GO; GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
DR   GO; GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
//
ID   CTBP2_HUMAN             Reviewed;         445 AA.
AC   P56545; A8K2X5; D3DRF5; O43449; Q5SQP7; Q69YI3; Q86SV0; Q9H2T8;
DE   RecName: Full=C-terminal-binding protein 2;
DE            Short=CtBP2;
GN   Name=CTBP2;
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
DR   GO; GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
//
ID   CTC1_HUMAN              Reviewed;        1217 AA.
AC   Q2NKJ3; B3KR66; C9JEX5; Q1PCD1; Q2TBE3; Q8N3S6; Q9H6L0;
DE   RecName: Full=CST complex subunit CTC1;
DE   AltName: Full=Conserved telomere maintenance component 1;
DE   AltName: Full=HBV DNAPTP1-transactivated protein B;
GN   Name=CTC1; Synonyms=C17orf68;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0048539; P:bone marrow development; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0090399; P:replicative senescence; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0010833; P:telomere maintenance via telomere lengthening; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   CTCFL_HUMAN             Reviewed;         663 AA.
AC   Q8NI51; A0S6W1; A1L4C6; A6XGL8; A6XGM2; A6XGM3; A6XGM8; A6XGN0;
AC   A6XGN1; A6XGN2; A6XGN3; A6XGN4; E7EQ27; E7EUE3; E9PBA9; Q5JUG4;
AC   Q9BZ30; Q9NQJ3;
DE   RecName: Full=Transcriptional repressor CTCFL;
DE   AltName: Full=Brother of the regulator of imprinted sites;
DE   AltName: Full=CCCTC-binding factor;
DE   AltName: Full=CTCF paralog;
DE   AltName: Full=CTCF-like protein;
DE   AltName: Full=Cancer/testis antigen 27;
DE            Short=CT27;
DE   AltName: Full=Zinc finger protein CTCF-T;
GN   Name=CTCFL; Synonyms=BORIS;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0016571; P:histone methylation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; ISS:UniProtKB.
DR   GO; GO:0051569; P:regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CTCF_HUMAN              Reviewed;         727 AA.
AC   P49711; B5MC38; Q53XI7; Q59EL8;
DE   RecName: Full=Transcriptional repressor CTCF;
DE   AltName: Full=11-zinc finger protein;
DE   AltName: Full=CCCTC-binding factor;
DE   AltName: Full=CTCFL paralog;
GN   Name=CTCF;
DR   GO; GO:0043035; F:chromatin insulator sequence binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0010216; P:maintenance of DNA methylation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016584; P:nucleosome positioning; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0070602; P:regulation of centromeric sister chromatid cohesion; NAS:UniProtKB.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0040029; P:regulation of gene expression, epigenetic; IMP:UniProtKB.
DR   GO; GO:0035065; P:regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0031060; P:regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:0040030; P:regulation of molecular function, epigenetic; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CTDP1_HUMAN             Reviewed;         961 AA.
AC   Q9Y5B0; A8MY97; Q7Z644; Q96BZ1; Q9Y6F5;
DE   RecName: Full=RNA polymerase II subunit A C-terminal domain phosphatase;
DE            EC=3.1.3.16;
DE   AltName: Full=TFIIF-associating CTD phosphatase;
GN   Name=CTDP1; Synonyms=FCP1;
DR   GO; GO:0008420; F:CTD phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0010458; P:exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CTDS1_HUMAN             Reviewed;         261 AA.
AC   Q9GZU7; C9IYG0; Q7Z5Q3; Q7Z5Q4;
DE   RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1;
DE            EC=3.1.3.16;
DE   AltName: Full=Nuclear LIM interactor-interacting factor 3;
DE            Short=NLI-IF;
DE            Short=NLI-interacting factor 3;
DE   AltName: Full=Small C-terminal domain phosphatase 1;
DE            Short=SCP1;
DE            Short=Small CTD phosphatase 1;
GN   Name=CTDSP1; Synonyms=NIF3, NLIIF, SCP1;
DR   GO; GO:0008420; F:CTD phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   CTDS2_HUMAN             Reviewed;         271 AA.
AC   O14595; A8K5H4; Q53ZR2; Q6NZY3; Q9UEX1;
DE   RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2;
DE            EC=3.1.3.16;
DE   AltName: Full=Nuclear LIM interactor-interacting factor 2;
DE            Short=NLI-interacting factor 2;
DE   AltName: Full=Protein OS-4;
DE   AltName: Full=Small C-terminal domain phosphatase 2;
DE   AltName: Full=Small CTD phosphatase 2;
DE            Short=SCP2;
GN   Name=CTDSP2; Synonyms=NIF2, OS4, SCP2;
DR   GO; GO:0008420; F:CTD phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
//
ID   CTDSL_HUMAN             Reviewed;         276 AA.
AC   O15194; Q3ZTU0; Q70KI4; Q7Z5Q2;
DE   RecName: Full=CTD small phosphatase-like protein;
DE            Short=CTDSP-like;
DE            EC=3.1.3.16;
DE   AltName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3;
DE   AltName: Full=NIF-like protein;
DE   AltName: Full=Nuclear LIM interactor-interacting factor 1;
DE            Short=NLI-interacting factor 1;
DE   AltName: Full=Protein YA22;
DE            Short=hYA22;
DE   AltName: Full=RBSP3;
DE   AltName: Full=Small C-terminal domain phosphatase 3;
DE            Short=SCP3;
DE            Short=Small CTD phosphatase 3;
GN   Name=CTDSPL; Synonyms=C3orf8, NIF1, NIFL, SCP3, YA22;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
//
ID   CTF18_HUMAN             Reviewed;         975 AA.
AC   Q8WVB6; B7ZBA2; D3DU68; Q7Z6Y4; Q7Z6Y6; Q9BR83; Q9BRG5; Q9H7K3;
DE   RecName: Full=Chromosome transmission fidelity protein 18 homolog;
DE            Short=hCTF18;
DE   AltName: Full=CHL12;
GN   Name=CHTF18; Synonyms=C16orf41, CTF18;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   CTF1_HUMAN              Reviewed;         201 AA.
AC   Q16619; A8MVX4; Q5U5Y7;
DE   RecName: Full=Cardiotrophin-1;
DE            Short=CT-1;
GN   Name=CTF1;
DR   GO; GO:0005146; F:leukemia inhibitory factor receptor binding; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048861; P:leukemia inhibitory factor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   CTF8_HUMAN              Reviewed;         121 AA.
AC   P0CG13; A8MYX8; Q71E72; Q8NDH8; Q8WV66; Q9NX73;
DE   RecName: Full=Chromosome transmission fidelity protein 8 homolog;
DE            Short=hCTF8;
GN   Name=CHTF8; Synonyms=CTF8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   CTF8A_HUMAN             Reviewed;         524 AA.
AC   P0CG12; A8MYX8; Q71E72; Q8NDH8; Q8WV66; Q9NX73;
DE   RecName: Full=Chromosome transmission fidelity protein 8 homolog isoform 2;
DE   AltName: Full=Decreased expression in renal and prostate cancer protein;
GN   Name=CHTF8; Synonyms=DERPC;
//
ID   CTGE1_HUMAN             Reviewed;          74 AA.
AC   Q9HC47; B0YIZ3;
DE   RecName: Full=Cutaneous T-cell lymphoma-associated antigen 1;
DE            Short=Protein cTAGE-1;
DE   AltName: Full=Cancer/testis antigen 21.1;
DE            Short=CT21.1;
GN   Name=CTAGE1; Synonyms=CTAGE2;
//
ID   CTG1B_HUMAN             Reviewed;         180 AA.
AC   P78358; A1L417; B7WNL9; Q7LBY4; Q9NY13;
DE   RecName: Full=Cancer/testis antigen 1;
DE   AltName: Full=Autoimmunogenic cancer/testis antigen NY-ESO-1;
DE   AltName: Full=Cancer/testis antigen 6.1;
DE            Short=CT6.1;
DE   AltName: Full=L antigen family member 2;
DE            Short=LAGE-2;
GN   Name=CTAG1A; Synonyms=CTAG, CTAG1, ESO1, LAGE2, LAGE2A;
GN   and
GN   Name=CTAG1B; Synonyms=LAGE2B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CTGE2_HUMAN             Reviewed;         745 AA.
AC   Q96RT6; A2RUF2;
DE   RecName: Full=cTAGE family member 2;
DE            Short=Protein cTAGE-2;
DE   AltName: Full=Cancer/testis antigen 21.2;
DE            Short=CT21.2;
GN   Name=CTAGE1; Synonyms=CTAGE2;
//
ID   CTGE4_HUMAN             Reviewed;         777 AA.
AC   Q8IX94; A8K871; O95046;
DE   RecName: Full=cTAGE family member 4;
DE            Short=Protein cTAGE-4;
GN   Name=CTAGE4;
//
ID   CTGE3_HUMAN             Reviewed;         158 AA.
AC   Q8IX95;
DE   RecName: Full=Putative cTAGE family member 3;
DE            Short=Protein cTAGE-3;
GN   Name=CTAGE3P; Synonyms=CTAGE3;
//
ID   CTGE5_HUMAN             Reviewed;         804 AA.
AC   O15320; B3KRA6; B4DQS6; D3DSA6; G3XAC5; O00169; Q6MZN2; Q6P2R8;
AC   Q86TF6; Q8IX92; Q8IX93;
DE   RecName: Full=cTAGE family member 5;
DE            Short=Protein cTAGE-5;
DE   AltName: Full=Meningioma-expressed antigen 6/11;
GN   Name=CTAGE5; Synonyms=MEA11, MEA6, MGEA11, MGEA6;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
//
ID   CTGE6_HUMAN             Reviewed;         777 AA.
AC   Q86UF2; A4FU29; Q3ZCM5;
DE   RecName: Full=cTAGE family member 6;
DE            Short=Protein cTAGE-6;
GN   Name=CTAGE6; Synonyms=CTAGE6P;
//
ID   CTGE8_HUMAN             Reviewed;         777 AA.
AC   P0CG41;
DE   RecName: Full=cTAGE family member 8;
DE            Short=Protein cTAGE-8;
GN   Name=CTAGE8;
//
ID   CTGE9_HUMAN             Reviewed;         777 AA.
AC   A4FU28;
DE   RecName: Full=cTAGE family member 9;
DE            Short=Protein cTAGE-9;
GN   Name=CTAGE9;
//
ID   CTGEF_HUMAN             Reviewed;         777 AA.
AC   A4D2H0; A6H8Z8;
DE   RecName: Full=cTAGE family member 15;
DE            Short=Protein cTAGE-15;
GN   Name=CTAGE15; Synonyms=CTAGE15P;
//
ID   CTGF_HUMAN              Reviewed;         349 AA.
AC   P29279; E1P578; Q6LCY0; Q96A79; Q96QX2; Q9UDL6;
DE   RecName: Full=Connective tissue growth factor;
DE   AltName: Full=CCN family member 2;
DE   AltName: Full=Hypertrophic chondrocyte-specific protein 24;
DE   AltName: Full=Insulin-like growth factor-binding protein 8;
DE            Short=IBP-8;
DE            Short=IGF-binding protein 8;
DE            Short=IGFBP-8;
DE   Flags: Precursor;
GN   Name=CTGF; Synonyms=CCN2, HCS24, IGFBP8;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005520; F:insulin-like growth factor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0035988; P:chondrocyte proliferation; IEA:Ensembl.
DR   GO; GO:0060401; P:cytosolic calcium ion transport; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0070278; P:extracellular matrix constituent secretion; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010260; P:organ senescence; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0060452; P:positive regulation of cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0050867; P:positive regulation of cell activation; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0070318; P:positive regulation of G0 to G1 transition; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:BHF-UCL.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0034059; P:response to anoxia; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0051385; P:response to mineralocorticoid; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   CTHR1_HUMAN             Reviewed;         243 AA.
AC   Q96CG8; G3V141; Q6UW91; Q8IX63;
DE   RecName: Full=Collagen triple helix repeat-containing protein 1;
DE   AltName: Full=Protein NMTC1;
DE   Flags: Precursor;
GN   Name=CTHRC1; ORFNames=UNQ762/PRO1550;
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0090177; P:establishment of planar polarity involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0060122; P:inner ear receptor stereocilium organization; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0043932; P:ossification involved in bone remodeling; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   CTIF_HUMAN              Reviewed;         598 AA.
AC   O43310; B3KTR8; Q8IVD5;
DE   RecName: Full=CBP80/20-dependent translation initiation factor;
GN   Name=CTIF; Synonyms=KIAA0427;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0006446; P:regulation of translational initiation; IMP:UniProtKB.
//
ID   CTL1_HUMAN              Reviewed;         657 AA.
AC   Q8WWI5; A6NLZ9; Q5VUB3; Q8WVB0; Q96KU3; Q9NY69;
DE   RecName: Full=Choline transporter-like protein 1;
DE   AltName: Full=CDw92;
DE   AltName: Full=Solute carrier family 44 member 1;
DE   AltName: CD_antigen=CD92;
GN   Name=SLC44A1; Synonyms=CD92, CDW92, CTL1;
DR   GuidetoPHARMACOLOGY; 1204; -.
DR   GO; GO:0015220; F:choline transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0015871; P:choline transport; TAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CTL2_HUMAN              Reviewed;         706 AA.
AC   Q8IWA5; B2RBB1; B3KNH3; B4DFJ0; F2Q9D7; Q658V1; Q658Z2; Q6PJV7;
AC   Q8N2F0; Q9NY68;
DE   RecName: Full=Choline transporter-like protein 2;
DE   AltName: Full=Solute carrier family 44 member 2;
GN   Name=SLC44A2; Synonyms=CTL2; ORFNames=PSEC0210;
DR   GO; GO:0015220; F:choline transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0015871; P:choline transport; TAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CTL3_HUMAN              Reviewed;         653 AA.
AC   Q8N4M1; B4DVY4; B4E1M4; B7ZA08; E9PJH2; E9PJY8; Q6UWT1; Q7Z6C5;
AC   Q9BWY7;
DE   RecName: Full=Choline transporter-like protein 3;
DE   AltName: Full=Solute carrier family 44 member 3;
GN   Name=SLC44A3; Synonyms=CTL3; ORFNames=UNQ558/PRO1115;
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CTL4_HUMAN              Reviewed;         710 AA.
AC   Q53GD3; A2BED3; B0UXX8; B0UZY8; B4DU94; B4DWM2; E9PEK7; Q5JP84;
AC   Q5JQ93; Q658S8; Q6UX89; Q8TEW4; Q96C58; Q96K59; Q9Y332;
DE   RecName: Full=Choline transporter-like protein 4;
DE   AltName: Full=Solute carrier family 44 member 4;
GN   Name=SLC44A4; Synonyms=C6orf29, CTL4, NG22; ORFNames=UNQ441/PRO874;
DR   GO; GO:0008292; P:acetylcholine biosynthetic process; IMP:UniProt.
DR   GO; GO:0061526; P:acetylcholine secretion; IMP:UniProt.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProt.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CTL5_HUMAN              Reviewed;         719 AA.
AC   Q8NCS7; B5MCU3; Q4G0K0; Q8NA44; Q8NB86;
DE   RecName: Full=Choline transporter-like protein 5;
DE   AltName: Full=Solute carrier family 44 member 5;
GN   Name=SLC44A5; Synonyms=CTL5;
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CTLA4_HUMAN             Reviewed;         223 AA.
AC   P16410; A0N1S0; E9PDH0; O95653; Q0PP65; Q52MC1; Q53TD5; Q5S005;
AC   Q8WXJ1; Q96P43; Q9UKN9;
DE   RecName: Full=Cytotoxic T-lymphocyte protein 4;
DE   AltName: Full=Cytotoxic T-lymphocyte-associated antigen 4;
DE            Short=CTLA-4;
DE   AltName: CD_antigen=CD152;
DE   Flags: Precursor;
GN   Name=CTLA4; Synonyms=CD152;
DR   GuidetoPHARMACOLOGY; 2743; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050777; P:negative regulation of immune response; IEA:Ensembl.
DR   GO; GO:0045590; P:negative regulation of regulatory T cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   CTLFB_HUMAN             Reviewed;         671 AA.
AC   A8MT82;
DE   RecName: Full=Putative centaurin-gamma-like family member 11P;
GN   Name=CTGLF11P;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   CTNA1_HUMAN             Reviewed;         906 AA.
AC   P35221; Q12795; Q8N1C0;
DE   RecName: Full=Catenin alpha-1;
DE   AltName: Full=Alpha E-catenin;
DE   AltName: Full=Cadherin-associated protein;
DE   AltName: Full=Renal carcinoma antigen NY-REN-13;
GN   Name=CTNNA1;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; IPI:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0043297; P:apical junction assembly; NAS:UniProtKB.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0016264; P:gap junction assembly; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2000146; P:negative regulation of cell motility; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:2001045; P:negative regulation of integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
//
ID   CTNA2_HUMAN             Reviewed;         953 AA.
AC   P26232; B3KXE5; B7Z2W7; B7Z352; B7Z898; Q4ZFW1; Q53R26; Q53R33;
AC   Q53T67; Q53T71; Q53TM8; Q7Z3L1; Q7Z3Y0;
DE   RecName: Full=Catenin alpha-2;
DE   AltName: Full=Alpha N-catenin;
DE   AltName: Full=Alpha-catenin-related protein;
GN   Name=CTNNA2; Synonyms=CAPR;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0060134; P:prepulse inhibition; ISS:UniProtKB.
DR   GO; GO:0021942; P:radial glia guided migration of Purkinje cell; ISS:UniProtKB.
DR   GO; GO:0051823; P:regulation of synapse structural plasticity; ISS:UniProtKB.
//
ID   CTNA3_HUMAN             Reviewed;         895 AA.
AC   Q9UI47; Q5VSR2; Q6P056;
DE   RecName: Full=Catenin alpha-3;
DE   AltName: Full=Alpha T-catenin;
DE   AltName: Full=Cadherin-associated protein;
GN   Name=CTNNA3;
DR   GO; GO:0045296; F:cadherin binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IPI:UniProtKB.
//
ID   CTNB1_HUMAN             Reviewed;         781 AA.
AC   P35222; A8K1L7; Q8NEW9; Q8NI94; Q9H391;
DE   RecName: Full=Catenin beta-1;
DE   AltName: Full=Beta-catenin;
GN   Name=CTNNB1; Synonyms=CTNNB; ORFNames=OK/SW-cl.35, PRO2286;
DR   GO; GO:0045294; F:alpha-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0045296; F:cadherin binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0030331; F:estrogen receptor binding; IPI:BHF-UCL.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IBA:RefGenome.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; NAS:ProtInc.
DR   GO; GO:0046332; F:SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IBA:RefGenome.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0034333; P:adherens junction assembly; IMP:BHF-UCL.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0044336; P:canonical Wnt signaling pathway involved in negative regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0061324; P:canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0044334; P:canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IBA:RefGenome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0022009; P:central nervous system vasculogenesis; IBA:RefGenome.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; IBA:RefGenome.
DR   GO; GO:0048262; P:determination of dorsal/ventral asymmetry; IBA:RefGenome.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IBA:RefGenome.
DR   GO; GO:0007398; P:ectoderm development; IBA:RefGenome.
DR   GO; GO:0000578; P:embryonic axis specification; IBA:RefGenome.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IBA:RefGenome.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IBA:RefGenome.
DR   GO; GO:0036023; P:embryonic skeletal limb joint morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001711; P:endodermal cell fate commitment; IBA:RefGenome.
DR   GO; GO:0061154; P:endothelial tube morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060742; P:epithelial cell differentiation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; TAS:HGNC.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0061198; P:fungiform papilla formation; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IBA:RefGenome.
DR   GO; GO:0035112; P:genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0007403; P:glial cell fate determination; IBA:RefGenome.
DR   GO; GO:0035315; P:hair cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IBA:RefGenome.
DR   GO; GO:0060789; P:hair follicle placode formation; IBA:RefGenome.
DR   GO; GO:0030902; P:hindbrain development; IBA:RefGenome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; IEA:Ensembl.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IBA:RefGenome.
DR   GO; GO:0060479; P:lung cell differentiation; IBA:RefGenome.
DR   GO; GO:0060492; P:lung induction; IBA:RefGenome.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IBA:RefGenome.
DR   GO; GO:0030539; P:male genitalia development; IBA:RefGenome.
DR   GO; GO:0060916; P:mesenchymal cell proliferation involved in lung development; IBA:RefGenome.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IBA:RefGenome.
DR   GO; GO:0007494; P:midgut development; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IBA:RefGenome.
DR   GO; GO:0003136; P:negative regulation of heart induction by canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IBA:RefGenome.
DR   GO; GO:0033234; P:negative regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0072079; P:nephron tubule formation; IBA:RefGenome.
DR   GO; GO:0001840; P:neural plate development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IBA:RefGenome.
DR   GO; GO:0048599; P:oocyte development; IBA:RefGenome.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0060066; P:oviduct development; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IBA:RefGenome.
DR   GO; GO:0001569; P:patterning of blood vessels; IC:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0061047; P:positive regulation of branching involved in lung morphogenesis; IBA:RefGenome.
DR   GO; GO:2000017; P:positive regulation of determination of dorsal identity; IEA:Ensembl.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060769; P:positive regulation of epithelial cell proliferation involved in prostate gland development; IBA:RefGenome.
DR   GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0010909; P:positive regulation of heparan sulfate proteoglycan biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IBA:RefGenome.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IBA:RefGenome.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0034394; P:protein localization to cell surface; IMP:BHF-UCL.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IBA:RefGenome.
DR   GO; GO:0045765; P:regulation of angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0090279; P:regulation of calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0030997; P:regulation of centriole-centriole cohesion; IDA:UniProtKB.
DR   GO; GO:0070602; P:regulation of centromeric sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0048145; P:regulation of fibroblast proliferation; TAS:BHF-UCL.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000008; P:regulation of protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:0003266; P:regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:0048660; P:regulation of smooth muscle cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0042129; P:regulation of T cell proliferation; IBA:RefGenome.
DR   GO; GO:0072053; P:renal inner medulla development; IBA:RefGenome.
DR   GO; GO:0072054; P:renal outer medulla development; IBA:RefGenome.
DR   GO; GO:0072033; P:renal vesicle formation; IBA:RefGenome.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEP:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0014010; P:Schwann cell proliferation; IBA:RefGenome.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IBA:RefGenome.
DR   GO; GO:0050808; P:synapse organization; IBA:RefGenome.
DR   GO; GO:0048489; P:synaptic vesicle transport; IBA:RefGenome.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IBA:RefGenome.
DR   GO; GO:0048538; P:thymus development; IBA:RefGenome.
DR   GO; GO:0043587; P:tongue morphogenesis; IBA:RefGenome.
DR   GO; GO:0060440; P:trachea formation; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
//
ID   CTND1_HUMAN             Reviewed;         968 AA.
AC   O60716; A8K939; O15088; O60713; O60714; O60715; O60935; Q6DHZ7;
AC   Q6RBX8; Q9UP71; Q9UP72; Q9UP73;
DE   RecName: Full=Catenin delta-1;
DE   AltName: Full=Cadherin-associated Src substrate;
DE            Short=CAS;
DE   AltName: Full=p120 catenin;
DE            Short=p120(ctn);
DE   AltName: Full=p120(cas);
GN   Name=CTNND1; Synonyms=KIAA0384;
DR   GO; GO:0045296; F:cadherin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0060690; P:epithelial cell differentiation involved in salivary gland development; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001738; P:morphogenesis of a polarized epithelium; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CTND2_HUMAN             Reviewed;        1225 AA.
AC   Q9UQB3; B0FTZ7; O00379; O15390; O43206; O43840; Q13589; Q9UM66;
AC   Q9UPM3;
DE   RecName: Full=Catenin delta-2;
DE   AltName: Full=Delta-catenin;
DE   AltName: Full=GT24;
DE   AltName: Full=Neural plakophilin-related ARM-repeat protein;
DE            Short=NPRAP;
DE   AltName: Full=Neurojungin;
GN   Name=CTNND2; Synonyms=NPRAP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CTNL1_HUMAN             Reviewed;         734 AA.
AC   Q9UBT7; B5BU47; O76084; Q53FQ2; Q5JTQ7; Q5JTQ8; Q9Y401;
DE   RecName: Full=Alpha-catulin;
DE   AltName: Full=Alpha-catenin-related protein;
DE            Short=ACRP;
DE   AltName: Full=Catenin alpha-like protein 1;
GN   Name=CTNNAL1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:MGI.
//
ID   CTNS_HUMAN              Reviewed;         367 AA.
AC   O60931; D3DTJ5; Q8IZ01; Q9UNK6;
DE   RecName: Full=Cystinosin;
GN   Name=CTNS;
DR   GO; GO:0015184; F:L-cystine transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0046034; P:ATP metabolic process; IMP:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; NAS:UniProtKB.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0048058; P:compound eye corneal lens development; IEA:Ensembl.
DR   GO; GO:0006749; P:glutathione metabolic process; IMP:UniProtKB.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0015811; P:L-cystine transport; IDA:MGI.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   CTR1_HUMAN              Reviewed;         629 AA.
AC   P30825; Q5JR50;
DE   RecName: Full=High affinity cationic amino acid transporter 1;
DE            Short=CAT-1;
DE            Short=CAT1;
DE   AltName: Full=Ecotropic retroviral leukemia receptor homolog;
DE   AltName: Full=Ecotropic retrovirus receptor homolog;
DE            Short=ERR;
DE   AltName: Full=Solute carrier family 7 member 1;
DE   AltName: Full=System Y+ basic amino acid transporter;
GN   Name=SLC7A1; Synonyms=ATRC1, ERR, REC1L;
DR   GO; GO:0015181; F:arginine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   CTR2_HUMAN              Reviewed;         658 AA.
AC   P52569; B7ZL54; O15291; O15292; Q14CQ6; Q6NSZ7; Q86TC6;
DE   RecName: Full=Low affinity cationic amino acid transporter 2;
DE            Short=CAT-2;
DE            Short=CAT2;
DE   AltName: Full=Solute carrier family 7 member 2;
GN   Name=SLC7A2; Synonyms=ATRC2, CAT2;
DR   GO; GO:0015174; F:basic amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005289; F:high affinity arginine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015189; F:L-lysine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0000064; F:L-ornithine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0042116; P:macrophage activation; IEA:Ensembl.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0002537; P:nitric oxide production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043030; P:regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CTR3L_HUMAN             Reviewed;         142 AA.
AC   Q7Z475; M0QY13;
DE   RecName: Full=Putative cationic amino acid transporter 3-like protein;
DE   Flags: Precursor;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
//
ID   CTR3_HUMAN              Reviewed;         619 AA.
AC   Q8WY07; D3DVU7; Q5JQR2; Q8N185; Q8NCA7; Q96SZ7;
DE   RecName: Full=Cationic amino acid transporter 3;
DE            Short=CAT-3;
DE            Short=CAT3;
DE   AltName: Full=Cationic amino acid transporter y+;
DE   AltName: Full=Solute carrier family 7 member 3;
GN   Name=SLC7A3; Synonyms=ATRC3, CAT3;
DR   GO; GO:0015181; F:arginine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015326; F:cationic amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015189; F:L-lysine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CTR4_HUMAN              Reviewed;         635 AA.
AC   O43246; Q0P5U2; Q3KNQ6; Q4VC45; Q6IBY8; Q96H88;
DE   RecName: Full=Cationic amino acid transporter 4;
DE            Short=CAT-4;
DE            Short=CAT4;
DE   AltName: Full=Solute carrier family 7 member 4;
GN   Name=SLC7A4;
DR   GO; GO:0015174; F:basic amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015802; P:basic amino acid transport; TAS:GOC.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CTR9_HUMAN              Reviewed;        1173 AA.
AC   Q6PD62; D3DQV8; Q15015;
DE   RecName: Full=RNA polymerase-associated protein CTR9 homolog;
DE   AltName: Full=SH2 domain-binding protein 1;
GN   Name=CTR9; Synonyms=KIAA0155, SH2BP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007259; P:JAK-STAT cascade; ISS:UniProtKB.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CTRB1_HUMAN             Reviewed;         263 AA.
AC   P17538;
DE   RecName: Full=Chymotrypsinogen B;
DE            EC=3.4.21.1;
DE   Contains:
DE     RecName: Full=Chymotrypsin B chain A;
DE   Contains:
DE     RecName: Full=Chymotrypsin B chain B;
DE   Contains:
DE     RecName: Full=Chymotrypsin B chain C;
DE   Flags: Precursor;
GN   Name=CTRB1; Synonyms=CTRB;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   CTRB2_HUMAN             Reviewed;         263 AA.
AC   Q6GPI1; A8K707;
DE   RecName: Full=Chymotrypsinogen B2;
DE            EC=3.4.21.1;
DE   Contains:
DE     RecName: Full=Chymotrypsin B2 chain A;
DE   Contains:
DE     RecName: Full=Chymotrypsin B2 chain B;
DE   Contains:
DE     RecName: Full=Chymotrypsin B2 chain C;
DE   Flags: Precursor;
GN   Name=CTRB2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   CTRC_HUMAN              Reviewed;         268 AA.
AC   Q99895; A8K082; O00765; Q9NUH5;
DE   RecName: Full=Chymotrypsin-C;
DE            EC=3.4.21.2;
DE   AltName: Full=Caldecrin;
DE   Flags: Precursor;
GN   Name=CTRC; Synonyms=CLCR;
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CTRO_HUMAN              Reviewed;        2027 AA.
AC   O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7;
DE   RecName: Full=Citron Rho-interacting kinase;
DE            Short=CRIK;
DE            EC=2.7.11.1;
DE   AltName: Full=Serine/threonine-protein kinase 21;
GN   Name=CIT; Synonyms=CRIK, KIAA0949, STK21;
DR   GuidetoPHARMACOLOGY; 1509; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProt.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0048699; P:generation of neurons; ISS:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; ISS:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:Ensembl.
DR   GO; GO:0050774; P:negative regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   CTRL_HUMAN              Reviewed;         264 AA.
AC   P40313;
DE   RecName: Full=Chymotrypsin-like protease CTRL-1;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=CTRL; Synonyms=CTRL1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   CTSL2_HUMAN             Reviewed;         466 AA.
AC   Q05D32; Q3ZTU1; Q6AI06; Q8IYI9; Q9NVT2; Q9NZX8; Q9P030;
DE   RecName: Full=CTD small phosphatase-like protein 2;
DE            Short=CTDSP-like 2;
DE            EC=3.1.3.-;
GN   Name=CTDSPL2; ORFNames=HSPC058, HSPC129;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
//
ID   CTSR1_HUMAN             Reviewed;         780 AA.
AC   Q8NEC5; Q96P76;
DE   RecName: Full=Cation channel sperm-associated protein 1;
DE            Short=CatSper1;
DE            Short=hCatSper;
GN   Name=CATSPER1;
DR   GuidetoPHARMACOLOGY; 388; -.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0030317; P:sperm motility; IBA:RefGenome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CTSR2_HUMAN             Reviewed;         530 AA.
AC   Q96P56; Q8NHT9; Q96P54; Q96P55;
DE   RecName: Full=Cation channel sperm-associated protein 2;
DE            Short=CatSper2;
GN   Name=CATSPER2;
DR   GuidetoPHARMACOLOGY; 389; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0030317; P:sperm motility; IBA:RefGenome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CTSR3_HUMAN             Reviewed;         398 AA.
AC   Q86XQ3; Q86XS6;
DE   RecName: Full=Cation channel sperm-associated protein 3;
DE            Short=CatSper3;
DE   AltName: Full=Ca(v)-like protein;
DE   AltName: Full=One-repeat calcium channel-like protein;
GN   Name=CATSPER3;
DR   GuidetoPHARMACOLOGY; 390; -.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:Ensembl.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IBA:RefGenome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CTSR4_HUMAN             Reviewed;         472 AA.
AC   Q7RTX7; A1A4W6; Q5VY71;
DE   RecName: Full=Cation channel sperm-associated protein 4;
DE            Short=CatSper4;
GN   Name=CATSPER4;
DR   GuidetoPHARMACOLOGY; 391; -.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:Ensembl.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IBA:RefGenome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CTSRB_HUMAN             Reviewed;        1116 AA.
AC   Q9H7T0; A0AV51;
DE   RecName: Full=Cation channel sperm-associated protein subunit beta;
DE            Short=CatSper-beta;
GN   Name=CATSPERB; Synonyms=C14orf161;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CTSRD_HUMAN             Reviewed;         798 AA.
AC   Q86XM0; Q6ZRP1;
DE   RecName: Full=Cation channel sperm-associated protein subunit delta;
DE            Short=CatSper-delta;
DE            Short=CatSperdelta;
DE   AltName: Full=Transmembrane protein 146;
DE   Flags: Precursor;
GN   Name=CATSPERD; Synonyms=TMEM146;
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0048240; P:sperm capacitation; ISS:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; ISS:UniProtKB.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   CTSRG_HUMAN             Reviewed;        1159 AA.
AC   Q6ZRH7; A6NEG6; Q659E1;
DE   RecName: Full=Cation channel sperm-associated protein subunit gamma;
DE   Flags: Precursor;
GN   Name=CATSPERG; Synonyms=C19orf15;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CTTB2_HUMAN             Reviewed;        1663 AA.
AC   Q8WZ74; O43389; Q7LG11; Q9C0A5;
DE   RecName: Full=Cortactin-binding protein 2;
DE            Short=CortBP2;
GN   Name=CTTNBP2; Synonyms=C7orf8, CORTBP2, KIAA1758;
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
//
ID   CTU1_HUMAN              Reviewed;         348 AA.
AC   Q7Z7A3; A8K558; Q96GZ7;
DE   RecName: Full=Cytoplasmic tRNA 2-thiolation protein 1;
DE            EC=2.7.7.-;
DE   AltName: Full=ATP-binding domain-containing protein 3;
DE   AltName: Full=Cancer-associated gene protein;
DE   AltName: Full=Cytoplasmic tRNA adenylyltransferase 1;
GN   Name=CTU1; Synonyms=ATPBD3, NCS6;
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032447; P:protein urmylation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034227; P:tRNA thio-modification; NAS:UniProtKB.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; NAS:UniProtKB.
//
ID   CTU2_HUMAN              Reviewed;         515 AA.
AC   Q2VPK5; B2RXK0; Q0P511; Q66K78; Q6P4C8; Q86SV4;
DE   RecName: Full=Cytoplasmic tRNA 2-thiolation protein 2;
GN   Name=CTU2; Synonyms=C16orf84, NCS2;
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR   GO; GO:0032447; P:protein urmylation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034227; P:tRNA thio-modification; NAS:UniProtKB.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; NAS:UniProtKB.
//
ID   CTXN1_HUMAN             Reviewed;          82 AA.
AC   P60606;
DE   RecName: Full=Cortexin-1;
GN   Name=CTXN1; Synonyms=CTXN;
//
ID   CTXN2_HUMAN             Reviewed;          81 AA.
AC   P0C2S0;
DE   RecName: Full=Cortexin-2;
GN   Name=CTXN2;
//
ID   CTXN3_HUMAN             Reviewed;          81 AA.
AC   Q4LDR2; B2RV32; D3DQ82;
DE   RecName: Full=Cortexin-3;
DE   AltName: Full=Kidney and brain-expressed protein;
GN   Name=CTXN3; Synonyms=KABE;
//
ID   CU002_HUMAN             Reviewed;         256 AA.
AC   O43822; A8MPS9; O14993; Q8N5X6; Q99837; Q99838;
DE   RecName: Full=Protein C21orf2;
DE   AltName: Full=C21orf-HUMF09G8.5;
DE   AltName: Full=YF5/A2;
GN   Name=C21orf2;
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   CU024_HUMAN             Reviewed;         140 AA.
AC   Q6XXX2;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00114;
GN   Name=LINC00114; Synonyms=C21orf24, NCRNA00114;
//
ID   CU025_HUMAN             Reviewed;         696 AA.
AC   Q9Y426; Q5R2V7; Q6AHX8; Q9NSE6;
DE   RecName: Full=C2 domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=C2CD2; Synonyms=C21orf25, C21orf258;
//
ID   CU034_HUMAN             Reviewed;         104 AA.
AC   A1L4M7;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00478;
GN   Name=LINC00478; Synonyms=C21orf34, C21orf35;
//
ID   CU037_HUMAN             Reviewed;          74 AA.
AC   A6NIU2;
DE   RecName: Full=Putative uncharacterized protein C21orf37;
GN   Name=C21orf37;
//
ID   CU042_HUMAN             Reviewed;          81 AA.
AC   P58513;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00158;
GN   Name=LINC00158; Synonyms=C21orf42, NCRNA00158;
//
ID   CU049_HUMAN             Reviewed;          79 AA.
AC   Q17RA5;
DE   RecName: Full=Putative uncharacterized protein C21orf49;
GN   Name=C21orf49;
//
ID   CU054_HUMAN             Reviewed;         108 AA.
AC   A6NM66;
DE   RecName: Full=Uncharacterized protein C21orf54;
GN   Name=C21orf54;
//
ID   CU058_HUMAN             Reviewed;         322 AA.
AC   P58505; B3KPI1;
DE   RecName: Full=Uncharacterized protein C21orf58;
GN   Name=C21orf58;
//
ID   CU059_HUMAN             Reviewed;         290 AA.
AC   P57076; Q53FH0;
DE   RecName: Full=UPF0769 protein C21orf59;
GN   Name=C21orf59; Synonyms=C21orf48;
//
ID   CU062_HUMAN             Reviewed;         219 AA.
AC   Q9NYP8; A8K4L8;
DE   RecName: Full=Uncharacterized protein C21orf62;
DE   AltName: Full=B37;
GN   Name=C21orf62; Synonyms=C21orf120;
//
ID   CU067_HUMAN             Reviewed;         204 AA.
AC   P58512; P58556; Q495D3; Q495D5;
DE   RecName: Full=Uncharacterized protein C21orf67;
GN   Name=C21orf67; Synonyms=C21orf69;
//
ID   CU074_HUMAN             Reviewed;          52 AA.
AC   Q8TCZ7;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00308;
GN   Name=LINC00308; Synonyms=C21orf74, NCRNA00308; ORFNames=PRED16;
//
ID   CU077_HUMAN             Reviewed;         126 AA.
AC   Q9NV44; Q8N366;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00846;
GN   Name=LINC00846; Synonyms=C21orf77;
//
ID   CU082_HUMAN             Reviewed;          64 AA.
AC   P59036; Q52LY1;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00310;
GN   Name=LINC00310; Synonyms=C21orf82, NCRNA00310;
//
ID   CU086_HUMAN             Reviewed;         165 AA.
AC   P59089;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00205;
GN   Name=LINC00205; Synonyms=C21orf86, NCRNA00205;
//
ID   CU084_HUMAN             Reviewed;          77 AA.
AC   P59037; Q3KNU0;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00313;
GN   Name=LINC00313; Synonyms=C21orf84, NCRNA00313;
//
ID   CU088_HUMAN             Reviewed;         145 AA.
AC   P59052; Q0VDC1; Q547X5;
DE   RecName: Full=Putative uncharacterized protein C21orf88;
GN   Name=C21orf88;
//
ID   CU090_HUMAN             Reviewed;          65 AA.
AC   P59090; Q3MIX8;
DE   RecName: Full=Putative uncharacterized protein C21orf90;
GN   Name=C21orf90;
//
ID   CU093_HUMAN             Reviewed;         139 AA.
AC   P59091;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00315;
GN   Name=LINC00315; Synonyms=C21orf93, NCRNA00315;
//
ID   CU104_HUMAN             Reviewed;         153 AA.
AC   Q9UJ94;
DE   RecName: Full=Putative uncharacterized protein encoded C21orf104;
DE   Flags: Precursor;
GN   Name=LINC00527; Synonyms=C21orf104;
//
ID   CU113_HUMAN             Reviewed;          66 AA.
AC   P0C852;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00162;
DE   AltName: Full=Putative narcolepsy candidate region 1 gene C protein;
DE            Short=NLC1-C;
GN   Name=LINC00162; Synonyms=C21orf113, NCRNA00162;
//
ID   CU119_HUMAN             Reviewed;          61 AA.
AC   Q96HZ7;
DE   RecName: Full=Putative uncharacterized protein C21orf119;
GN   Name=C21orf119; ORFNames=PRED84;
//
ID   CU128_HUMAN             Reviewed;         162 AA.
AC   Q8N2C9;
DE   RecName: Full=Uncharacterized protein C21orf128;
GN   Name=C21orf128;
//
ID   CU129_HUMAN             Reviewed;         142 AA.
AC   Q96M42; D3DSJ3;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00479;
GN   Name=LINC00479; Synonyms=C21orf129; ORFNames=PRED76;
//
ID   CU136_HUMAN             Reviewed;         302 AA.
AC   Q6ZN03;
DE   RecName: Full=Uncharacterized protein encoded by LINC00322;
GN   Name=LINC00322; Synonyms=C21orf136, NCRNA00322;
//
ID   CU140_HUMAN             Reviewed;         251 AA.
AC   B9A014;
DE   RecName: Full=Uncharacterized protein C21orf140;
GN   Name=C21orf140;
//
ID   CUBN_HUMAN              Reviewed;        3623 AA.
AC   O60494; B0YIZ4; Q5VTA6; Q96RU9;
DE   RecName: Full=Cubilin;
DE   AltName: Full=460 kDa receptor;
DE   AltName: Full=Intestinal intrinsic factor receptor;
DE   AltName: Full=Intrinsic factor-cobalamin receptor;
DE   AltName: Full=Intrinsic factor-vitamin B12 receptor;
DE   Flags: Precursor;
GN   Name=CUBN; Synonyms=IFCR;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0015889; P:cobalamin transport; TAS:ProtInc.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0001894; P:tissue homeostasis; NAS:UniProtKB.
DR   GO; GO:0042359; P:vitamin D metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   CUED1_HUMAN             Reviewed;         386 AA.
AC   Q9NWM3; D3DTZ2; Q9NWD0;
DE   RecName: Full=CUE domain-containing protein 1;
GN   Name=CUEDC1;
//
ID   CUED2_HUMAN             Reviewed;         287 AA.
AC   Q9H467; D3DR88; Q9BWG8;
DE   RecName: Full=CUE domain-containing protein 2;
GN   Name=CUEDC2; Synonyms=C10orf66; ORFNames=HOYS6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CUL1_HUMAN              Reviewed;         776 AA.
AC   Q13616; D3DWG3; O60719; Q08AL6; Q8IYW1;
DE   RecName: Full=Cullin-1;
DE            Short=CUL-1;
GN   Name=CUL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CUL2_HUMAN              Reviewed;         745 AA.
AC   Q13617; B3KT95; B7Z6K8; D3DRY6; G3V1S2; O00200; Q5T2B6; Q9UNF9;
DE   RecName: Full=Cullin-2;
DE            Short=CUL-2;
GN   Name=CUL2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CUL3_HUMAN              Reviewed;         768 AA.
AC   Q13618; A8K536; B8ZZC3; O75415; Q569L3; Q9UBI8; Q9UET7;
DE   RecName: Full=Cullin-3;
DE            Short=CUL-3;
GN   Name=CUL3; Synonyms=KIAA0617;
DR   GO; GO:0031208; F:POZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051322; P:anaphase; IMP:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0048208; P:COPII vesicle coating; IMP:UniProtKB.
DR   GO; GO:0008054; P:cyclin catabolic process; IDA:MGI.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0040016; P:embryonic cleavage; ISS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0000090; P:mitotic anaphase; IMP:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0017145; P:stem cell division; ISS:UniProtKB.
DR   GO; GO:0043149; P:stress fiber assembly; IMP:UniProtKB.
DR   GO; GO:0001831; P:trophectodermal cellular morphogenesis; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   CUL4A_HUMAN             Reviewed;         759 AA.
AC   Q13619; A2A2W2; O75834; Q589T6; Q5TC62; Q6UP08; Q9UP17;
DE   RecName: Full=Cullin-4A;
DE            Short=CUL-4A;
GN   Name=CUL4A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0051246; P:regulation of protein metabolic process; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CUL4B_HUMAN             Reviewed;         913 AA.
AC   Q13620; B1APK5; B3KVX4; B7Z5K8; Q6PIE4; Q6UP07; Q7Z673; Q9BY37;
AC   Q9UEB7; Q9UED7;
DE   RecName: Full=Cullin-4B;
DE            Short=CUL-4B;
GN   Name=CUL4B; Synonyms=KIAA0695;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProt.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0070914; P:UV-damage excision repair; IDA:UniProt.
//
ID   CUL5_HUMAN              Reviewed;         780 AA.
AC   Q93034; A8K960; O14766; Q9BZC6;
DE   RecName: Full=Cullin-5;
DE            Short=CUL-5;
DE   AltName: Full=Vasopressin-activated calcium-mobilizing receptor 1;
DE            Short=VACM-1;
GN   Name=CUL5; Synonyms=VACM1;
DR   GO; GO:0005262; F:calcium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CUL7_HUMAN              Reviewed;        1698 AA.
AC   Q14999; B4DYZ0; F5H0L1; Q5T654;
DE   RecName: Full=Cullin-7;
DE            Short=CUL-7;
GN   Name=CUL7; Synonyms=KIAA0076;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007030; P:Golgi organization; ISS:UniProtKB.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IGI:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CUL9_HUMAN              Reviewed;        2517 AA.
AC   Q8IWT3; O75188; Q5TCY3; Q68CP2; Q68D92; Q8N3W9; Q9BU56;
DE   RecName: Full=Cullin-9;
DE            Short=CUL-9;
DE   AltName: Full=UbcH7-associated protein 1;
DE   AltName: Full=p53-associated parkin-like cytoplasmic protein;
GN   Name=CUL9; Synonyms=H7AP1, KIAA0708, PARC;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   CUTA_HUMAN              Reviewed;         179 AA.
AC   O60888; A2AB26; A2BEL4; Q3B784; Q5JXM9; Q5SU05; Q9NYQ9;
DE   RecName: Full=Protein CutA;
DE   AltName: Full=Acetylcholinesterase-associated protein;
DE   AltName: Full=Brain acetylcholinesterase putative membrane anchor;
DE   Flags: Precursor;
GN   Name=CUTA; Synonyms=ACHAP, C6orf82;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
DR   GO; GO:0010038; P:response to metal ion; IEA:InterPro.
//
ID   CUTC_HUMAN              Reviewed;         273 AA.
AC   Q9NTM9; Q5TCZ8; Q9Y321;
DE   RecName: Full=Copper homeostasis protein cutC homolog;
GN   Name=CUTC; ORFNames=CGI-32;
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0055070; P:copper ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0006825; P:copper ion transport; NAS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IPI:UniProtKB.
//
ID   CUX1_HUMAN              Reviewed;        1505 AA.
AC   P39880; B3KV79; J3KQV9; Q6NYH4; Q75LE5; Q75MT2; Q75MT3; Q86UJ7;
AC   Q9UEV5;
DE   RecName: Full=Homeobox protein cut-like 1;
DE   AltName: Full=CCAAT displacement protein;
DE            Short=CDP;
DE   AltName: Full=Homeobox protein cux-1;
GN   Name=CUX1; Synonyms=CUTL1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; ISS:UniProt.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:UniProt.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0000301; P:retrograde transport, vesicle recycling within Golgi; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CUX2_HUMAN              Reviewed;        1486 AA.
AC   O14529; A7E2Y4;
DE   RecName: Full=Homeobox protein cut-like 2;
DE   AltName: Full=Homeobox protein cux-2;
GN   Name=CUX2; Synonyms=CUTL2, KIAA0293;
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; ISS:UniProt.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0050890; P:cognition; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProt.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:UniProt.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProt.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:UniProt.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProt.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:UniProt.
DR   GO; GO:0007614; P:short-term memory; ISS:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CUZD1_HUMAN             Reviewed;         607 AA.
AC   Q86UP6; A8K080; B2RN93; D3DRE5; Q7Z660; Q7Z661; Q86SG1; Q86UP5;
AC   Q9HAR7;
DE   RecName: Full=CUB and zona pellucida-like domain-containing protein 1;
DE            Short=CUB and ZP domain-containing protein 1;
DE   AltName: Full=Transmembrane protein UO-44;
DE   Flags: Precursor;
GN   Name=CUZD1; ORFNames=UNQ224/PRO257;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0006931; P:substrate-dependent cell migration, cell attachment to substrate; NAS:UniProtKB.
DR   GO; GO:0032023; P:trypsinogen activation; ISS:UniProtKB.
//
ID   CV015_HUMAN             Reviewed;         148 AA.
AC   Q8WYQ4; Q6ICJ7;
DE   RecName: Full=Uncharacterized protein C22orf15;
DE   AltName: Full=Protein N27C7-3;
GN   Name=C22orf15;
//
ID   CV024_HUMAN             Reviewed;         160 AA.
AC   Q9Y442; B2RCT4; Q5K3R1;
DE   RecName: Full=Uncharacterized protein C22orf24;
GN   Name=C22orf24;
//
ID   CV031_HUMAN             Reviewed;         290 AA.
AC   O95567; A0AV97;
DE   RecName: Full=Uncharacterized protein C22orf31;
GN   Name=C22orf31;
//
ID   CV034_HUMAN             Reviewed;         151 AA.
AC   Q6ZV56; Q147Y0; Q5R3D1; Q6ZTN8;
DE   RecName: Full=Uncharacterized protein C22orf34;
GN   Name=C22orf34;
//
ID   CV037_HUMAN             Reviewed;         170 AA.
AC   Q8N1L1;
DE   RecName: Full=Putative uncharacterized protein encoded LINC00528;
GN   Name=LINC00528; Synonyms=C22orf37;
//
ID   CV039_HUMAN             Reviewed;         142 AA.
AC   Q6P5X5; A8MTW6; D3DX18; F5H3A8; J3KNP9;
DE   RecName: Full=UPF0545 protein C22orf39;
GN   Name=C22orf39;
//
ID   CV042_HUMAN             Reviewed;         251 AA.
AC   Q6IC83; A4QPH5;
DE   RecName: Full=Uncharacterized protein C22orf42;
GN   Name=C22orf42;
//
ID   CV046_HUMAN             Reviewed;         243 AA.
AC   C9J442;
DE   RecName: Full=Uncharacterized protein C22orf46;
DE   Flags: Precursor;
GN   Name=C22orf46;
//
ID   CWC15_HUMAN             Reviewed;         229 AA.
AC   Q9P013; B2RC17; Q05BV9; Q05DM1; Q9UI29;
DE   RecName: Full=Spliceosome-associated protein CWC15 homolog;
GN   Name=CWC15; Synonyms=C11orf5; ORFNames=AD-002, HSPC148;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
//
ID   CWC22_HUMAN             Reviewed;         908 AA.
AC   Q9HCG8; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6;
DE   RecName: Full=Pre-mRNA-splicing factor CWC22 homolog;
DE   AltName: Full=Nucampholin homolog;
DE   AltName: Full=fSAPb;
GN   Name=CWC22; Synonyms=KIAA1604, NCM;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   CWC25_HUMAN             Reviewed;         425 AA.
AC   Q9NXE8; A0JLM3; Q68DK5;
DE   RecName: Full=Pre-mRNA-splicing factor CWC25 homolog;
DE   AltName: Full=Coiled-coil domain-containing protein 49;
DE   AltName: Full=Spliceosome-associated protein homolog CWC25;
GN   Name=CWC25; Synonyms=CCDC49;
//
ID   CWC27_HUMAN             Reviewed;         472 AA.
AC   Q6UX04; O60529; O60530; Q96EM3;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase CWC27 homolog;
DE            Short=PPIase CWC27;
DE            EC=5.2.1.8;
DE   AltName: Full=Antigen NY-CO-10;
DE   AltName: Full=Serologically defined colon cancer antigen 10;
GN   Name=CWC27; Synonyms=SDCCAG10; ORFNames=UNQ438/PRO871;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   CX021_HUMAN             Reviewed;         301 AA.
AC   Q9HAI6;
DE   RecName: Full=Uncharacterized protein CXorf21;
GN   Name=CXorf21;
//
ID   CX022_HUMAN             Reviewed;         976 AA.
AC   Q6ZTR5; Q5JRM8; Q8N6X8;
DE   RecName: Full=Uncharacterized protein CXorf22;
GN   Name=CXorf22;
//
ID   CX023_HUMAN             Reviewed;         711 AA.
AC   A2AJT9; A1A4E8; Q5VSM7; Q5VSN1; Q6ZS60; Q8N1W7;
DE   RecName: Full=Uncharacterized protein CXorf23;
GN   Name=CXorf23;
//
ID   CX024_HUMAN             Reviewed;          94 AA.
AC   Q8TB33; Q5H9B1;
DE   RecName: Full=Putative uncharacterized protein CXorf24;
GN   Name=CXorf24;
//
ID   CX028_HUMAN             Reviewed;          62 AA.
AC   A6NGU7;
DE   RecName: Full=Putative uncharacterized protein CXorf28;
GN   Name=CXorf28;
//
ID   CX030_HUMAN             Reviewed;         633 AA.
AC   A6PW82;
DE   RecName: Full=Putative uncharacterized protein CXorf30;
GN   Name=CXorf30;
//
ID   CX031_HUMAN             Reviewed;          79 AA.
AC   Q5VT33;
DE   RecName: Full=Putative uncharacterized protein CXorf31;
GN   Name=CXorf31;
//
ID   CX038_HUMAN             Reviewed;         319 AA.
AC   Q8TB03; B3KW28; D3DWB5; Q5JPF5; Q8N941;
DE   RecName: Full=Uncharacterized protein CXorf38;
GN   Name=CXorf38;
//
ID   CX042_HUMAN             Reviewed;         125 AA.
AC   Q8N9T2; Q05CP2; Q14CJ5; Q7Z3P3;
DE   RecName: Full=Putative uncharacterized protein CXorf42;
DE   AltName: Full=NF-kappa-B-activating protein pseudogene 1;
GN   Name=NKAPP1; Synonyms=CXorf42;
//
ID   CX049_HUMAN             Reviewed;         512 AA.
AC   A8MYA2;
DE   RecName: Full=Putative uncharacterized protein CXorf49;
GN   Name=CXorf49;
GN   and
GN   Name=CXorf49B;
//
ID   CX04A_HUMAN             Reviewed;         158 AA.
AC   Q8TE69; A8K784; B7Z6H6; B7ZL96; D6RA72; E7ENU3; Q2M3E9;
DE   RecName: Full=Protein CXorf40A;
DE   AltName: Full=Endothelial-overexpressed lipopolysaccharide-associated factor 1;
GN   Name=CXorf40A; Synonyms=CXorf40, EOLA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   CX04B_HUMAN             Reviewed;         158 AA.
AC   Q96DE9;
DE   RecName: Full=Protein CXorf40B;
GN   Name=CXorf40B;
//
ID   CX056_HUMAN             Reviewed;         222 AA.
AC   Q9H5V9; A8MPX7; B4DQN2; D3DWH9; F5GWL7; O43351;
DE   RecName: Full=UPF0428 protein CXorf56;
GN   Name=CXorf56;
//
ID   CX057_HUMAN             Reviewed;         855 AA.
AC   Q6NSI4; H7BY89; Q4G0L7; Q5JQS1; Q5JRF9; Q6PHY5; Q6PII9; Q6PJU8;
AC   Q9H7W5; Q9NWA6;
DE   RecName: Full=Uncharacterized protein CXorf57;
GN   Name=CXorf57;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   CX062_HUMAN             Reviewed;         174 AA.
AC   Q8N2A0;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00269;
GN   Name=LINC00269; Synonyms=CXorf62, NCRNA00269;
//
ID   CX058_HUMAN             Reviewed;         332 AA.
AC   Q96LI9;
DE   RecName: Full=Putative uncharacterized protein CXorf58;
GN   Name=CXorf58;
//
ID   CX065_HUMAN             Reviewed;         183 AA.
AC   A6NEN9;
DE   RecName: Full=Uncharacterized protein CXorf65;
GN   Name=CXorf65;
//
ID   CX066_HUMAN             Reviewed;         361 AA.
AC   Q5JRM2;
DE   RecName: Full=Uncharacterized protein CXorf66;
DE   Flags: Precursor;
GN   Name=CXorf66;
//
ID   CX067_HUMAN             Reviewed;         503 AA.
AC   Q86X51;
DE   RecName: Full=Uncharacterized protein CXorf67;
GN   Name=CXorf67;
//
ID   CX3C1_HUMAN             Reviewed;         355 AA.
AC   P49238; A0N0N6; B2R5Z4; J3KP17;
DE   RecName: Full=CX3C chemokine receptor 1;
DE            Short=C-X3-C CKR-1;
DE            Short=CX3CR1;
DE   AltName: Full=Beta chemokine receptor-like 1;
DE   AltName: Full=CMK-BRL-1;
DE            Short=CMK-BRL1;
DE   AltName: Full=Fractalkine receptor;
DE   AltName: Full=G-protein coupled receptor 13;
DE   AltName: Full=V28;
GN   Name=CX3CR1; Synonyms=CMKBRL1, GPR13;
DR   GuidetoPHARMACOLOGY; 74; -.
DR   GO; GO:0016495; F:C-X3-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048246; P:macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CX6A1_HUMAN             Reviewed;         109 AA.
AC   P12074; B2R500; O43714; Q32Q37;
DE   RecName: Full=Cytochrome c oxidase subunit 6A1, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIa-liver;
DE   AltName: Full=Cytochrome c oxidase subunit VIA-liver;
DE            Short=COX VIa-L;
DE   Flags: Precursor;
GN   Name=COX6A1; Synonyms=COX6AL;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CX6A2_HUMAN             Reviewed;          97 AA.
AC   Q02221; O00761; Q6GTW6;
DE   RecName: Full=Cytochrome c oxidase subunit 6A2, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIa-heart;
DE            Short=COXVIAH;
DE   AltName: Full=Cytochrome c oxidase subunit VIA-muscle;
DE            Short=COX VIa-M;
DE   Flags: Precursor;
GN   Name=COX6A2; Synonyms=COX6A, COX6AH;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
//
ID   CX6B1_HUMAN             Reviewed;          86 AA.
AC   P14854; B2R5C9; Q6IBL4;
DE   RecName: Full=Cytochrome c oxidase subunit 6B1;
DE   AltName: Full=Cytochrome c oxidase subunit VIb isoform 1;
DE            Short=COX VIb-1;
GN   Name=COX6B1; Synonyms=COX6B;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; NAS:GOC.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   CX6B2_HUMAN             Reviewed;          88 AA.
AC   Q6YFQ2; Q7L1R4; Q96DL5;
DE   RecName: Full=Cytochrome c oxidase subunit 6B2;
DE   AltName: Full=Cancer/testis antigen 59;
DE            Short=CT59;
DE   AltName: Full=Cytochrome c oxidase subunit VIb isoform 2;
DE            Short=COX VIb-2;
DE   AltName: Full=Cytochrome c oxidase subunit VIb, testis-specific isoform;
GN   Name=COX6B2;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
//
ID   CX7A1_HUMAN             Reviewed;          79 AA.
AC   P24310;
DE   RecName: Full=Cytochrome c oxidase subunit 7A1, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase subunit VIIa-heart;
DE            Short=Cytochrome c oxidase subunit VIIa-H;
DE   AltName: Full=Cytochrome c oxidase subunit VIIa-muscle;
DE            Short=Cytochrome c oxidase subunit VIIa-M;
DE   Flags: Precursor;
GN   Name=COX7A1; Synonyms=COX7AH;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
//
ID   CX7A2_HUMAN             Reviewed;          83 AA.
AC   P14406; B2R5E1; Q3MIH5; Q5TF59; Q6FGI2;
DE   RecName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase subunit VIIa-liver/heart;
DE            Short=Cytochrome c oxidase subunit VIIa-L;
DE            Short=Cytochrome c oxidase subunit VIIaL;
DE   Flags: Precursor;
GN   Name=COX7A2; Synonyms=COX7AL;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
//
ID   CX7B2_HUMAN             Reviewed;          81 AA.
AC   Q8TF08; Q32Q40;
DE   RecName: Full=Cytochrome c oxidase subunit 7B2, mitochondrial;
DE   AltName: Full=Cytochrome c oxidase polypeptide VIIb2;
DE   Flags: Precursor;
GN   Name=COX7B2;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
//
ID   CXA10_HUMAN             Reviewed;         543 AA.
AC   Q969M2;
DE   RecName: Full=Gap junction alpha-10 protein;
DE   AltName: Full=Connexin-62;
DE            Short=Cx62;
GN   Name=GJA10; Synonyms=CX62;
DR   GuidetoPHARMACOLOGY; 734; -.
DR   GO; GO:0005243; F:gap junction channel activity; TAS:Reactome.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
//
ID   CXA1_HUMAN              Reviewed;         382 AA.
AC   P17302; B2R5U9; Q6FHU1; Q9Y5I8;
DE   RecName: Full=Gap junction alpha-1 protein;
DE   AltName: Full=Connexin-43;
DE            Short=Cx43;
DE   AltName: Full=Gap junction 43 kDa heart protein;
GN   Name=GJA1; Synonyms=GJAL;
DR   GuidetoPHARMACOLOGY; 728; -.
DR   GO; GO:0005243; F:gap junction channel activity; IDA:BHF-UCL.
DR   GO; GO:0015075; F:ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0015867; P:ATP transport; IEA:Ensembl.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; TAS:BHF-UCL.
DR   GO; GO:0010644; P:cell communication by electrical coupling; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0003158; P:endothelium development; IEA:Ensembl.
DR   GO; GO:0016264; P:gap junction assembly; TAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:2000987; P:positive regulation of behavioral fear response; IEA:Ensembl.
DR   GO; GO:0010652; P:positive regulation of cell communication by chemical coupling; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0003104; P:positive regulation of glomerular filtration; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IEA:Ensembl.
DR   GO; GO:0034405; P:response to fluid shear stress; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0055085; P:transmembrane transport; IDA:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0010232; P:vascular transport; IEA:Ensembl.
//
ID   CXA3_HUMAN              Reviewed;         435 AA.
AC   Q9Y6H8; Q0VAB7; Q9H537;
DE   RecName: Full=Gap junction alpha-3 protein;
DE   AltName: Full=Connexin-46;
DE            Short=Cx46;
GN   Name=GJA3;
DR   GuidetoPHARMACOLOGY; 730; -.
DR   GO; GO:0005243; F:gap junction channel activity; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CXA4_HUMAN              Reviewed;         333 AA.
AC   P35212; A8K698; D3DPR4; Q9P106; Q9UBL1; Q9UNA9; Q9UNB0; Q9UNB1;
AC   Q9Y5N7;
DE   RecName: Full=Gap junction alpha-4 protein;
DE   AltName: Full=Connexin-37;
DE            Short=Cx37;
GN   Name=GJA4;
DR   GuidetoPHARMACOLOGY; 725; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0003158; P:endothelium development; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CXA5_HUMAN              Reviewed;         358 AA.
AC   P36382; Q5T3B6; Q5U0N6;
DE   RecName: Full=Gap junction alpha-5 protein;
DE   AltName: Full=Connexin-40;
DE            Short=Cx40;
GN   Name=GJA5;
DR   GuidetoPHARMACOLOGY; 726; -.
DR   GO; GO:0086077; F:gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling; IDA:BHF-UCL.
DR   GO; GO:0086075; F:gap junction channel activity involved in cardiac conduction electrical coupling; IDA:BHF-UCL.
DR   GO; GO:0055077; F:gap junction hemi-channel activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0003283; P:atrial septum development; IMP:BHF-UCL.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003294; P:atrial ventricular junction remodeling; IEA:Ensembl.
DR   GO; GO:0086053; P:AV node cell to bundle of His cell communication by electrical coupling; IMP:BHF-UCL.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0003161; P:cardiac conduction system development; IEA:Ensembl.
DR   GO; GO:0010643; P:cell communication by chemical coupling; IEA:Ensembl.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; IDA:BHF-UCL.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0003158; P:endothelium development; IEA:Ensembl.
DR   GO; GO:0035922; P:foramen ovale closure; IEA:Ensembl.
DR   GO; GO:0016264; P:gap junction assembly; IDA:BHF-UCL.
DR   GO; GO:0003174; P:mitral valve development; IMP:BHF-UCL.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0003105; P:negative regulation of glomerular filtration; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0010652; P:positive regulation of cell communication by chemical coupling; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
DR   GO; GO:0003193; P:pulmonary valve formation; IMP:BHF-UCL.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IEA:Ensembl.
DR   GO; GO:1900825; P:regulation of membrane depolarization during cardiac muscle cell action potential; IEA:Ensembl.
DR   GO; GO:1900133; P:regulation of renin secretion into blood stream; IEA:Ensembl.
DR   GO; GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IEA:Ensembl.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IEA:Ensembl.
DR   GO; GO:0086015; P:SA node cell action potential; IEA:Ensembl.
DR   GO; GO:0003284; P:septum primum development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; IDA:GOC.
DR   GO; GO:1990029; P:vasomotion; IEA:Ensembl.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IMP:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
//
ID   CXA8_HUMAN              Reviewed;         433 AA.
AC   P48165; A7L5M5; Q5VVN9; Q9NP25;
DE   RecName: Full=Gap junction alpha-8 protein;
DE   AltName: Full=Connexin-50;
DE            Short=Cx50;
DE   AltName: Full=Lens fiber protein MP70;
GN   Name=GJA8;
DR   GuidetoPHARMACOLOGY; 732; -.
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   CXA9_HUMAN              Reviewed;         515 AA.
AC   P57773; B2R722; B3KVQ2; Q5TA63; Q96KG0;
DE   RecName: Full=Gap junction alpha-9 protein;
DE   AltName: Full=Connexin-58;
DE            Short=Cx58;
DE   AltName: Full=Connexin-59;
DE            Short=Cx59;
DE   AltName: Full=Gap junction alpha-10 protein;
GN   Name=GJA9; Synonyms=GJA10;
DR   GuidetoPHARMACOLOGY; 733; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
//
ID   CXAR_HUMAN              Reviewed;         365 AA.
AC   P78310; B2R8V8; B7WPI3; D3YHP0; O00694; Q8WWT6; Q8WWT7; Q8WWT8;
AC   Q9UKV4;
DE   RecName: Full=Coxsackievirus and adenovirus receptor;
DE            Short=CAR;
DE            Short=hCAR;
DE   AltName: Full=CVB3-binding protein;
DE   AltName: Full=Coxsackievirus B-adenovirus receptor;
DE   AltName: Full=HCVADR;
DE   Flags: Precursor;
GN   Name=CXADR; Synonyms=CAR;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:UniProtKB.
DR   GO; GO:0071253; F:connexin binding; ISS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0086067; P:AV node cell to bundle of His cell communication; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048739; P:cardiac muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0010669; P:epithelial structure maintenance; IMP:UniProtKB.
DR   GO; GO:0046629; P:gamma-delta T cell activation; ISS:UniProtKB.
DR   GO; GO:0008354; P:germ cell migration; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IMP:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0070633; P:transepithelial transport; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   CXB1_HUMAN              Reviewed;         283 AA.
AC   P08034; B2R8R2; D3DVV2; Q5U0S4;
DE   RecName: Full=Gap junction beta-1 protein;
DE   AltName: Full=Connexin-32;
DE            Short=Cx32;
DE   AltName: Full=GAP junction 28 kDa liver protein;
GN   Name=GJB1; Synonyms=CX32;
DR   GuidetoPHARMACOLOGY; 723; -.
DR   GO; GO:0005243; F:gap junction channel activity; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0016264; P:gap junction assembly; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
DR   GO; GO:0015868; P:purine ribonucleotide transport; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CXB2_HUMAN              Reviewed;         226 AA.
AC   P29033; Q508A5; Q508A6; Q5YLL0; Q5YLL1; Q5YLL4; Q6IPV5; Q86U88;
AC   Q96AK0; Q9H536; Q9NNY4;
DE   RecName: Full=Gap junction beta-2 protein;
DE   AltName: Full=Connexin-26;
DE            Short=Cx26;
GN   Name=GJB2;
DR   GuidetoPHARMACOLOGY; 716; -.
DR   GO; GO:0005243; F:gap junction channel activity; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0016264; P:gap junction assembly; TAS:Reactome.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   CXB3_HUMAN              Reviewed;         270 AA.
AC   O75712; B2R790; Q2TAZ8;
DE   RecName: Full=Gap junction beta-3 protein;
DE   AltName: Full=Connexin-31;
DE            Short=Cx31;
GN   Name=GJB3; Synonyms=CX31;
DR   GuidetoPHARMACOLOGY; 720; -.
DR   GO; GO:0005243; F:gap junction channel activity; NAS:UniProtKB.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; NAS:GOC.
//
ID   CXB4_HUMAN              Reviewed;         266 AA.
AC   Q9NTQ9; B3KQ82;
DE   RecName: Full=Gap junction beta-4 protein;
DE   AltName: Full=Connexin-30.3;
DE            Short=Cx30.3;
GN   Name=GJB4;
DR   GuidetoPHARMACOLOGY; 719; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0042048; P:olfactory behavior; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
//
ID   CXB5_HUMAN              Reviewed;         273 AA.
AC   O95377; Q9UPA3;
DE   RecName: Full=Gap junction beta-5 protein;
DE   AltName: Full=Connexin-31.1;
DE            Short=Cx31.1;
GN   Name=GJB5;
DR   GuidetoPHARMACOLOGY; 721; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0060713; P:labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0060708; P:spongiotrophoblast differentiation; IEA:Ensembl.
//
ID   CXB6_HUMAN              Reviewed;         261 AA.
AC   O95452; B3KQN2; Q5Q1H9; Q5Q1I0; Q5Q1I1; Q5T5U0; Q8IUP0;
DE   RecName: Full=Gap junction beta-6 protein;
DE   AltName: Full=Connexin-30;
DE            Short=Cx30;
GN   Name=GJB6;
DR   GuidetoPHARMACOLOGY; 717; -.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0042471; P:ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   CXB7_HUMAN              Reviewed;         223 AA.
AC   Q6PEY0; B3KXL0; Q96KP0;
DE   RecName: Full=Gap junction beta-7 protein;
DE   AltName: Full=Connexin-25;
DE            Short=Cx25;
GN   Name=GJB7; Synonyms=CX25;
DR   GuidetoPHARMACOLOGY; 715; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
//
ID   CXCL2_HUMAN             Reviewed;         107 AA.
AC   P19875; Q6FGD6; Q9UPB8;
DE   RecName: Full=C-X-C motif chemokine 2;
DE   AltName: Full=Growth-regulated protein beta;
DE            Short=Gro-beta;
DE   AltName: Full=Macrophage inflammatory protein 2-alpha;
DE            Short=MIP2-alpha;
DE   Contains:
DE     RecName: Full=GRO-beta(5-73);
DE     AltName: Full=GRO-beta-T;
DE     AltName: Full=Hematopoietic synergistic factor;
DE              Short=HSF;
DE     AltName: Full=SB-251353;
DE   Flags: Precursor;
GN   Name=CXCL2; Synonyms=GRO2, GROB, MIP2A, SCYB2;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IDA:BHF-UCL.
//
ID   CXCL3_HUMAN             Reviewed;         107 AA.
AC   P19876; Q4W5H9;
DE   RecName: Full=C-X-C motif chemokine 3;
DE   AltName: Full=GRO-gamma(1-73);
DE   AltName: Full=Growth-regulated protein gamma;
DE            Short=GRO-gamma;
DE   AltName: Full=Macrophage inflammatory protein 2-beta;
DE            Short=MIP2-beta;
DE   Contains:
DE     RecName: Full=GRO-gamma(5-73);
DE   Flags: Precursor;
GN   Name=CXCL3; Synonyms=GRO3, GROG, SCYB3;
DR   GO; GO:0008009; F:chemokine activity; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB.
//
ID   CXCL7_HUMAN             Reviewed;         128 AA.
AC   P02775; B2R5F3; Q6IBJ8;
DE   RecName: Full=Platelet basic protein;
DE            Short=PBP;
DE   AltName: Full=C-X-C motif chemokine 7;
DE   AltName: Full=Leukocyte-derived growth factor;
DE            Short=LDGF;
DE   AltName: Full=Macrophage-derived growth factor;
DE            Short=MDGF;
DE   AltName: Full=Small-inducible cytokine B7;
DE   Contains:
DE     RecName: Full=Connective tissue-activating peptide III;
DE              Short=CTAP-III;
DE     AltName: Full=LA-PF4;
DE     AltName: Full=Low-affinity platelet factor IV;
DE   Contains:
DE     RecName: Full=TC-2;
DE   Contains:
DE     RecName: Full=Connective tissue-activating peptide III(1-81);
DE              Short=CTAP-III(1-81);
DE   Contains:
DE     RecName: Full=Beta-thromboglobulin;
DE              Short=Beta-TG;
DE   Contains:
DE     RecName: Full=Neutrophil-activating peptide 2(74);
DE              Short=NAP-2(74);
DE   Contains:
DE     RecName: Full=Neutrophil-activating peptide 2(73);
DE              Short=NAP-2(73);
DE   Contains:
DE     RecName: Full=Neutrophil-activating peptide 2;
DE              Short=NAP-2;
DE   Contains:
DE     RecName: Full=TC-1;
DE   Contains:
DE     RecName: Full=Neutrophil-activating peptide 2(1-66);
DE              Short=NAP-2(1-66);
DE   Contains:
DE     RecName: Full=Neutrophil-activating peptide 2(1-63);
DE              Short=NAP-2(1-63);
DE   Flags: Precursor;
GN   Name=PPBP; Synonyms=CTAP3, CXCL7, SCYB7, TGB1, THBGB1;
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060326; P:cell chemotaxis; IEA:GOC.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0015758; P:glucose transport; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
//
ID   CXCL5_HUMAN             Reviewed;         114 AA.
AC   P42830; Q96QE1;
DE   RecName: Full=C-X-C motif chemokine 5;
DE   AltName: Full=ENA-78(1-78);
DE   AltName: Full=Epithelial-derived neutrophil-activating protein 78;
DE   AltName: Full=Neutrophil-activating peptide ENA-78;
DE   AltName: Full=Small-inducible cytokine B5;
DE   Contains:
DE     RecName: Full=ENA-78(8-78);
DE   Contains:
DE     RecName: Full=ENA-78(9-78);
DE   Flags: Precursor;
GN   Name=CXCL5; Synonyms=ENA78, SCYB5;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CXCL6_HUMAN             Reviewed;         114 AA.
AC   P80162; B2R4X3; Q4W5D4;
DE   RecName: Full=C-X-C motif chemokine 6;
DE   AltName: Full=Chemokine alpha 3;
DE            Short=CKA-3;
DE   AltName: Full=Granulocyte chemotactic protein 2;
DE            Short=GCP-2;
DE   AltName: Full=Small-inducible cytokine B6;
DE   Contains:
DE     RecName: Full=Small-inducible cytokine B6, N-processed variant 1;
DE   Contains:
DE     RecName: Full=Small-inducible cytokine B6, N-processed variant 2;
DE   Contains:
DE     RecName: Full=Small-inducible cytokine B6, N-processed variant 3;
DE   Flags: Precursor;
GN   Name=CXCL6; Synonyms=GCP2, SCYB6;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CXCL9_HUMAN             Reviewed;         125 AA.
AC   Q07325; Q503B4;
DE   RecName: Full=C-X-C motif chemokine 9;
DE   AltName: Full=Gamma-interferon-induced monokine;
DE   AltName: Full=Monokine induced by interferon-gamma;
DE            Short=HuMIG;
DE            Short=MIG;
DE   AltName: Full=Small-inducible cytokine B9;
DE   Flags: Precursor;
GN   Name=CXCL9; Synonyms=CMK, MIG, SCYB9;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0048248; F:CXCR3 chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030816; P:positive regulation of cAMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CXCR1_HUMAN             Reviewed;         350 AA.
AC   P25024; B2R6Q3; Q2YEF8; Q2YEG4; Q2YEG5; Q2YEG7; Q2YEG8; Q53R18;
AC   Q6IN95; Q8N6T6; Q9P2T8; Q9P2T9; Q9P2U0; Q9P2U1; Q9P2U2;
DE   RecName: Full=C-X-C chemokine receptor type 1;
DE            Short=CXC-R1;
DE            Short=CXCR-1;
DE   AltName: Full=CDw128a;
DE   AltName: Full=High affinity interleukin-8 receptor A;
DE            Short=IL-8R A;
DE   AltName: Full=IL-8 receptor type 1;
DE   AltName: CD_antigen=CD181;
GN   Name=CXCR1; Synonyms=CMKAR1, IL8RA;
DR   GuidetoPHARMACOLOGY; 68; -.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0019959; F:interleukin-8 binding; IPI:UniProtKB.
DR   GO; GO:0004918; F:interleukin-8 receptor activity; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0038112; P:interleukin-8-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
//
ID   CXCR2_HUMAN             Reviewed;         360 AA.
AC   P25025; Q8IUZ1; Q9P2T6; Q9P2T7;
DE   RecName: Full=C-X-C chemokine receptor type 2;
DE            Short=CXC-R2;
DE            Short=CXCR-2;
DE   AltName: Full=CDw128b;
DE   AltName: Full=GRO/MGSA receptor;
DE   AltName: Full=High affinity interleukin-8 receptor B;
DE            Short=IL-8R B;
DE   AltName: Full=IL-8 receptor type 2;
DE   AltName: CD_antigen=CD182;
GN   Name=CXCR2; Synonyms=IL8RB;
DR   GuidetoPHARMACOLOGY; 69; -.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; IDA:UniProtKB.
DR   GO; GO:0019959; F:interleukin-8 binding; IPI:UniProtKB.
DR   GO; GO:0004918; F:interleukin-8 receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IDA:UniProtKB.
DR   GO; GO:0002438; P:acute inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; IDA:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0038112; P:interleukin-8-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0072173; P:metanephric tubule morphogenesis; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0033030; P:negative regulation of neutrophil apoptotic process; IEA:Ensembl.
DR   GO; GO:0042119; P:neutrophil activation; IDA:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   CXCR3_HUMAN             Reviewed;         368 AA.
AC   P49682; B2R982; O15185; Q7Z710; Q9P2T4; Q9P2T5;
DE   RecName: Full=C-X-C chemokine receptor type 3;
DE            Short=CXC-R3;
DE            Short=CXCR-3;
DE   AltName: Full=CKR-L2;
DE   AltName: Full=G protein-coupled receptor 9;
DE   AltName: Full=Interferon-inducible protein 10 receptor;
DE            Short=IP-10 receptor;
DE   AltName: CD_antigen=CD183;
GN   Name=CXCR3; Synonyms=GPR9;
DR   GuidetoPHARMACOLOGY; 70; -.
DR   GO; GO:0019958; F:C-X-C chemokine binding; IDA:UniProtKB.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0019956; F:chemokine binding; IPI:BHF-UCL.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071954; P:chemokine (C-C motif) ligand 11 production; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:1900118; P:negative regulation of execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0030816; P:positive regulation of cAMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:1900119; P:positive regulation of execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0002685; P:regulation of leukocyte migration; IEA:InterPro.
DR   GO; GO:0010818; P:T cell chemotaxis; IEA:Ensembl.
//
ID   CXCR4_HUMAN             Reviewed;         352 AA.
AC   P61073; B2R5N0; O60835; P30991; P56438; Q53S69; Q9BXA0; Q9UKN2;
DE   RecName: Full=C-X-C chemokine receptor type 4;
DE            Short=CXC-R4;
DE            Short=CXCR-4;
DE   AltName: Full=FB22;
DE   AltName: Full=Fusin;
DE   AltName: Full=HM89;
DE   AltName: Full=LCR1;
DE   AltName: Full=Leukocyte-derived seven transmembrane domain receptor;
DE            Short=LESTR;
DE   AltName: Full=Lipopolysaccharide-associated protein 3;
DE            Short=LAP-3;
DE            Short=LPS-associated protein 3;
DE   AltName: Full=NPYRL;
DE   AltName: Full=Stromal cell-derived factor 1 receptor;
DE            Short=SDF-1 receptor;
DE   AltName: CD_antigen=CD184;
GN   Name=CXCR4;
DR   GuidetoPHARMACOLOGY; 71; -.
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; NAS:UniProtKB.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0032027; F:myosin light chain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0001667; P:ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IMP:MGI.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; NAS:GOC.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0030260; P:entry into host cell; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0043217; P:myelin maintenance; ISS:BHF-UCL.
DR   GO; GO:0061351; P:neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0042119; P:neutrophil activation; IEA:InterPro.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0050920; P:regulation of chemotaxis; IMP:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   CXCR5_HUMAN             Reviewed;         372 AA.
AC   P32302; Q14811;
DE   RecName: Full=C-X-C chemokine receptor type 5;
DE            Short=CXC-R5;
DE            Short=CXCR-5;
DE   AltName: Full=Burkitt lymphoma receptor 1;
DE   AltName: Full=Monocyte-derived receptor 15;
DE            Short=MDR-15;
DE   AltName: CD_antigen=CD185;
GN   Name=CXCR5; Synonyms=BLR1, MDR15;
DR   GuidetoPHARMACOLOGY; 72; -.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
//
ID   CXCR6_HUMAN             Reviewed;         342 AA.
AC   O00574; O00575; Q9HCA5;
DE   RecName: Full=C-X-C chemokine receptor type 6;
DE            Short=CXC-R6;
DE            Short=CXCR-6;
DE   AltName: Full=CDw186;
DE   AltName: Full=G-protein coupled receptor STRL33;
DE   AltName: Full=G-protein coupled receptor bonzo;
DE   AltName: CD_antigen=CD186;
GN   Name=CXCR6; Synonyms=BONZO, STRL33, TYMSTR;
DR   GuidetoPHARMACOLOGY; 73; -.
DR   GO; GO:0016494; F:C-X-C chemokine receptor activity; IEA:Ensembl.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
//
ID   CXD2_HUMAN              Reviewed;         321 AA.
AC   Q9UKL4; Q2M241; Q9P2R0;
DE   RecName: Full=Gap junction delta-2 protein;
DE   AltName: Full=Connexin-36;
DE            Short=Cx36;
DE   AltName: Full=Gap junction alpha-9 protein;
GN   Name=GJD2; Synonyms=GJA9;
DR   GuidetoPHARMACOLOGY; 724; -.
DR   GO; GO:0005243; F:gap junction channel activity; TAS:Reactome.
DR   GO; GO:0001508; P:action potential; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   CXD4_HUMAN              Reviewed;         370 AA.
AC   Q96KN9; Q8N2R7;
DE   RecName: Full=Gap junction delta-4 protein;
DE   AltName: Full=Connexin-40.1;
DE            Short=Cx40.1;
GN   Name=GJD4; Synonyms=CX40.1;
DR   GuidetoPHARMACOLOGY; 727; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0014717; P:regulation of satellite cell activation involved in skeletal muscle regeneration; IEA:Ensembl.
//
ID   CXD3_HUMAN              Reviewed;         294 AA.
AC   Q8N144; Q6ZUW6;
DE   RecName: Full=Gap junction delta-3 protein;
DE   AltName: Full=Connexin-31.9;
DE            Short=Cx31.9;
DE   AltName: Full=Gap junction alpha-11 protein;
DE   AltName: Full=Gap junction chi-1 protein;
GN   Name=GJD3; Synonyms=GJA11, GJC1;
DR   GuidetoPHARMACOLOGY; 722; -.
DR   GO; GO:0005216; F:ion channel activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007154; P:cell communication; TAS:UniProtKB.
DR   GO; GO:0016264; P:gap junction assembly; IDA:UniProtKB.
//
ID   CXE1_HUMAN              Reviewed;         205 AA.
AC   A6NN92;
DE   RecName: Full=Gap junction epsilon-1 protein;
DE   AltName: Full=Connexin-23;
DE            Short=Cx23;
GN   Name=GJE1;
DR   GuidetoPHARMACOLOGY; 714; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
//
ID   CXG1_HUMAN              Reviewed;         396 AA.
AC   P36383; B3KW68; Q4VAY0;
DE   RecName: Full=Gap junction gamma-1 protein;
DE   AltName: Full=Connexin-45;
DE            Short=Cx45;
DE   AltName: Full=Gap junction alpha-7 protein;
GN   Name=GJC1; Synonyms=GJA7;
DR   GuidetoPHARMACOLOGY; 729; -.
DR   GO; GO:0005243; F:gap junction channel activity; IEA:Ensembl.
DR   GO; GO:0005216; F:ion channel activity; IEA:Ensembl.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; TAS:BHF-UCL.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:ProtInc.
DR   GO; GO:0016264; P:gap junction assembly; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   CXG2_HUMAN              Reviewed;         439 AA.
AC   Q5T442; O43440; Q7Z7J2; Q8IWJ9;
DE   RecName: Full=Gap junction gamma-2 protein;
DE   AltName: Full=Connexin-46.6;
DE            Short=Cx46.6;
DE   AltName: Full=Connexin-47;
DE            Short=Cx47;
DE   AltName: Full=Gap junction alpha-12 protein;
GN   Name=GJC2; Synonyms=GJA12;
DR   GuidetoPHARMACOLOGY; 731; -.
DR   GO; GO:0005243; F:gap junction channel activity; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
//
ID   CXG3_HUMAN              Reviewed;         279 AA.
AC   Q8NFK1; A4D296; Q86XI9;
DE   RecName: Full=Gap junction gamma-3 protein;
DE   AltName: Full=Connexin-30.2;
DE            Short=Cx30.2;
DE   AltName: Full=Connexin-31.3;
DE            Short=Cx31.3;
DE   AltName: Full=Gap junction epsilon-1 protein;
GN   Name=GJC3; Synonyms=GJE1;
DR   GuidetoPHARMACOLOGY; 718; -.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   CXL10_HUMAN             Reviewed;          98 AA.
AC   P02778; Q96QJ5;
DE   RecName: Full=C-X-C motif chemokine 10;
DE   AltName: Full=10 kDa interferon gamma-induced protein;
DE            Short=Gamma-IP10;
DE            Short=IP-10;
DE   AltName: Full=Small-inducible cytokine B10;
DE   Contains:
DE     RecName: Full=CXCL10(1-73);
DE   Flags: Precursor;
GN   Name=CXCL10; Synonyms=INP10, SCYB10;
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; TAS:ProtInc.
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0048248; F:CXCR3 chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:MGI.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IMP:UniProt.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030816; P:positive regulation of cAMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IEA:Ensembl.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:UniProtKB.
DR   GO; GO:0009306; P:protein secretion; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0010996; P:response to auditory stimulus; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0010818; P:T cell chemotaxis; IMP:UniProt.
//
ID   CXL11_HUMAN             Reviewed;          94 AA.
AC   O14625; Q53YA3; Q92840;
DE   RecName: Full=C-X-C motif chemokine 11;
DE   AltName: Full=Beta-R1;
DE   AltName: Full=H174;
DE   AltName: Full=Interferon gamma-inducible protein 9;
DE            Short=IP-9;
DE   AltName: Full=Interferon-inducible T-cell alpha chemoattractant;
DE            Short=I-TAC;
DE   AltName: Full=Small-inducible cytokine B11;
DE   Flags: Precursor;
GN   Name=CXCL11; Synonyms=ITAC, SCYB11, SCYB9B;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0048248; F:CXCR3 chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IMP:UniProt.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030816; P:positive regulation of cAMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0010818; P:T cell chemotaxis; IMP:UniProt.
//
ID   CXL13_HUMAN             Reviewed;         109 AA.
AC   O43927;
DE   RecName: Full=C-X-C motif chemokine 13;
DE   AltName: Full=Angie;
DE   AltName: Full=B cell-attracting chemokine 1;
DE            Short=BCA-1;
DE   AltName: Full=B lymphocyte chemoattractant;
DE   AltName: Full=CXC chemokine BLC;
DE   AltName: Full=Small-inducible cytokine B13;
DE   Flags: Precursor;
GN   Name=CXCL13; Synonyms=BCA1, BLC, SCYB13;
DR   GO; GO:0031735; F:CCR10 chemokine receptor binding; IDA:BHF-UCL.
DR   GO; GO:0008009; F:chemokine activity; IDA:BHF-UCL.
DR   GO; GO:0048248; F:CXCR3 chemokine receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031724; F:CXCR5 chemokine receptor binding; IDA:BHF-UCL.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0048018; F:receptor agonist activity; IDA:BHF-UCL.
DR   GO; GO:0032861; P:activation of Rap GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0035754; P:B cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0035769; P:B cell chemotaxis across high endothelial venule; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:BHF-UCL.
DR   GO; GO:0002544; P:chronic inflammatory response; NAS:BHF-UCL.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:BHF-UCL.
DR   GO; GO:0035768; P:endothelial cell chemotaxis to fibroblast growth factor; IDA:BHF-UCL.
DR   GO; GO:0002467; P:germinal center formation; NAS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IC:BHF-UCL.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0002518; P:lymphocyte chemotaxis across high endothelial venule; ISS:BHF-UCL.
DR   GO; GO:2000545; P:negative regulation of endothelial cell chemotaxis to fibroblast growth factor; IDA:BHF-UCL.
DR   GO; GO:0033634; P:positive regulation of cell-cell adhesion mediated by integrin; ISS:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:BHF-UCL.
DR   GO; GO:0033625; P:positive regulation of integrin activation; ISS:BHF-UCL.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0045765; P:regulation of angiogenesis; NAS:BHF-UCL.
DR   GO; GO:0002920; P:regulation of humoral immune response; NAS:BHF-UCL.
//
ID   CXL14_HUMAN             Reviewed;         111 AA.
AC   O95715; B3KQU8; Q6UW97; Q86U69; Q9BTR1; Q9NS21;
DE   RecName: Full=C-X-C motif chemokine 14;
DE   AltName: Full=Chemokine BRAK;
DE   AltName: Full=MIP-2G;
DE   AltName: Full=Small-inducible cytokine B14;
DE   Flags: Precursor;
GN   Name=CXCL14; Synonyms=MIP2G, NJAC, SCYB14;
GN   ORFNames=PSEC0212, UNQ240/PRO273;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CXL16_HUMAN             Reviewed;         254 AA.
AC   Q9H2A7; A0N0N4; A8K7U9; B2RCB0; Q8TC80; Q96K63; Q9BXD6; Q9H2F6;
DE   RecName: Full=C-X-C motif chemokine 16;
DE   AltName: Full=Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein;
DE            Short=SR-PSOX;
DE   AltName: Full=Small-inducible cytokine B16;
DE   AltName: Full=Transmembrane chemokine CXCL16;
DE   Flags: Precursor;
GN   Name=CXCL16; Synonyms=SCYB16, SRPSOX; ORFNames=UNQ2759/PRO6714;
DR   GO; GO:0008009; F:chemokine activity; ISS:UniProtKB.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; NAS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; TAS:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; NAS:UniProtKB.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; NAS:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.
//
ID   CXX1_HUMAN              Reviewed;         209 AA.
AC   O15255; Q6IBF1;
DE   RecName: Full=CAAX box protein 1;
DE   AltName: Full=Cerebral protein 5;
DE   Flags: Precursor;
GN   Name=FAM127A; Synonyms=CXX1, MAR8, MAR8C, MART8; ORFNames=hucep-5;
//
ID   CXXC1_HUMAN             Reviewed;         656 AA.
AC   Q9P0U4; B2RC03; Q8N2W4; Q96BC8; Q9P2V7;
DE   RecName: Full=CXXC-type zinc finger protein 1;
DE   AltName: Full=CpG-binding protein;
DE   AltName: Full=PHD finger and CXXC domain-containing protein 1;
GN   Name=CXXC1; Synonyms=CFP1, CGBP, PCCX1, PHF18;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045322; F:unmethylated CpG binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   CXXC4_HUMAN             Reviewed;         198 AA.
AC   Q9H2H0;
DE   RecName: Full=CXXC-type zinc finger protein 4;
DE   AltName: Full=Inhibition of the Dvl and axin complex protein;
GN   Name=CXXC4; Synonyms=IDAX;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007352; P:zygotic specification of dorsal/ventral axis; ISS:BHF-UCL.
//
ID   CXXC5_HUMAN             Reviewed;         322 AA.
AC   Q7LFL8; B3KND0; C8CBA8; Q8TB79; Q9NV51; Q9P0S8;
DE   RecName: Full=CXXC-type zinc finger protein 5;
DE            Short=CF5;
DE   AltName: Full=Putative MAPK-activating protein PM08;
DE   AltName: Full=Putative NF-kappa-B-activating protein 102;
DE   AltName: Full=Retinoid-inducible nuclear factor;
DE            Short=RINF;
GN   Name=CXXC5; ORFNames=HSPC195, TCCCIA00297;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   CY017_HUMAN             Reviewed;         182 AA.
AC   Q9H606;
DE   RecName: Full=Putative uncharacterized protein CYorf17;
GN   Name=CYorf17;
//
ID   CY1_HUMAN               Reviewed;         325 AA.
AC   P08574; Q5U062; Q6FHS7;
DE   RecName: Full=Cytochrome c1, heme protein, mitochondrial;
DE   AltName: Full=Complex III subunit 4;
DE   AltName: Full=Complex III subunit IV;
DE   AltName: Full=Cytochrome b-c1 complex subunit 4;
DE   AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit;
DE            Short=Cytochrome c-1;
DE   Flags: Precursor;
GN   Name=CYC1;
DR   GO; GO:0045155; F:electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; TAS:ProtInc.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CY24A_HUMAN             Reviewed;         195 AA.
AC   P13498; Q14090; Q9BR72;
DE   RecName: Full=Cytochrome b-245 light chain;
DE   AltName: Full=Cytochrome b(558) alpha chain;
DE   AltName: Full=Cytochrome b558 subunit alpha;
DE   AltName: Full=Neutrophil cytochrome b 22 kDa polypeptide;
DE   AltName: Full=Superoxide-generating NADPH oxidase light chain subunit;
DE   AltName: Full=p22 phagocyte B-cytochrome;
DE   AltName: Full=p22-phox;
DE            Short=p22phox;
GN   Name=CYBA;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:Ensembl.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0017004; P:cytochrome complex assembly; IDA:BHF-UCL.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IMP:BHF-UCL.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0003106; P:negative regulation of glomerular filtration by angiotensin; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IMP:BHF-UCL.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045730; P:respiratory burst; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0014895; P:smooth muscle hypertrophy; ISS:BHF-UCL.
DR   GO; GO:0042554; P:superoxide anion generation; IMP:BHF-UCL.
DR   GO; GO:0006801; P:superoxide metabolic process; IMP:BHF-UCL.
//
ID   CY24B_HUMAN             Reviewed;         570 AA.
AC   P04839; A8K138; Q2PP16;
DE   RecName: Full=Cytochrome b-245 heavy chain;
DE            EC=1.-.-.-;
DE   AltName: Full=CGD91-phox;
DE   AltName: Full=Cytochrome b(558) subunit beta;
DE            Short=Cytochrome b558 subunit beta;
DE   AltName: Full=Heme-binding membrane glycoprotein gp91phox;
DE   AltName: Full=NADPH oxidase 2;
DE   AltName: Full=Neutrophil cytochrome b 91 kDa polypeptide;
DE   AltName: Full=Superoxide-generating NADPH oxidase heavy chain subunit;
DE   AltName: Full=gp91-1;
DE   AltName: Full=gp91-phox;
DE   AltName: Full=p22 phagocyte B-cytochrome;
GN   Name=CYBB; Synonyms=NOX2;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IMP:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IMP:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; TAS:BHF-UCL.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IMP:BHF-UCL.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0045730; P:respiratory burst; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; IDA:BHF-UCL.
DR   GO; GO:0006801; P:superoxide metabolic process; IDA:BHF-UCL.
//
ID   CY561_HUMAN             Reviewed;         251 AA.
AC   P49447; B2RE96; D3DU11; Q5BJG9; Q9BU05; Q9BWR9;
DE   RecName: Full=Cytochrome b561;
DE   AltName: Full=Cytochrome b-561;
GN   Name=CYB561;
DR   GO; GO:0000293; F:ferric-chelate reductase activity; ISS:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0022865; F:transmembrane electron transfer carrier; NAS:UniProtKB.
DR   GO; GO:0022900; P:electron transport chain; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; NAS:GOC.
//
ID   CYAC3_HUMAN             Reviewed;         242 AA.
AC   Q8NBI2; B3KPU2; B4DLN9; J3KQH4; Q6PK96;
DE   RecName: Full=Cytochrome b ascorbate-dependent protein 3;
DE            EC=1.-.-.-;
DE   AltName: Full=Cytochrome b561 family member A3;
DE   AltName: Full=Lysosomal cytochrome b;
DE            Short=LCytb;
GN   Name=CYB561A3; Synonyms=CYBASC3, LCYTB; ORFNames=PSEC0259;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   CYB5B_HUMAN             Reviewed;         146 AA.
AC   O43169; A8K6B1; Q96CC3; Q9BT35;
DE   RecName: Full=Cytochrome b5 type B;
DE   AltName: Full=Cytochrome b5 outer mitochondrial membrane isoform;
DE   Flags: Precursor;
GN   Name=CYB5B; Synonyms=CYB5M, OMB5;
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
//
ID   CYB5_HUMAN              Reviewed;         134 AA.
AC   P00167; A8MV91; F8WEU4; Q6IB14;
DE   RecName: Full=Cytochrome b5;
DE   AltName: Full=Microsomal cytochrome b5 type A;
DE            Short=MCB5;
GN   Name=CYB5A; Synonyms=CYB5;
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:Reactome.
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; TAS:Reactome.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   CYBP_HUMAN              Reviewed;         228 AA.
AC   Q9HB71; B2ZWH2; B3KSF1; O60666; Q5R370; Q5R371;
DE   RecName: Full=Calcyclin-binding protein;
DE            Short=CacyBP;
DE            Short=hCacyBP;
DE   AltName: Full=S100A6-binding protein;
DE   AltName: Full=Siah-interacting protein;
GN   Name=CACYBP; Synonyms=S100A6BP, SIP; ORFNames=PNAS-107;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0060416; P:response to growth hormone; IEA:Ensembl.
//
ID   CYBR1_HUMAN             Reviewed;         286 AA.
AC   Q53TN4; B2RE79; B4DWD7; Q6KC16; Q6KC17; Q6P147; Q6ZR51; Q9H0Q8;
AC   Q9H5G5;
DE   RecName: Full=Cytochrome b reductase 1;
DE            EC=1.-.-.-;
DE   AltName: Full=Duodenal cytochrome b;
DE   AltName: Full=Ferric-chelate reductase 3;
GN   Name=CYBRD1; Synonyms=DCYTB, FRRS3;
DR   GO; GO:0000293; F:ferric-chelate reductase activity; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016722; F:oxidoreductase activity, oxidizing metal ions; TAS:Reactome.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   CYB_HUMAN               Reviewed;         380 AA.
AC   P00156; Q34786; Q8HBR6; Q8HNQ0; Q8HNQ1; Q8HNQ9; Q8HNR4; Q8HNR7;
AC   Q8W7V8; Q8WCV9; Q8WCY2; Q8WCY7; Q8WCY8; Q9B1A6; Q9B1B6; Q9B1B8;
AC   Q9B1D4; Q9B1X6; Q9B2V0; Q9B2V8; Q9B2W0; Q9B2W3; Q9B2W8; Q9B2X1;
AC   Q9B2X7; Q9B2X9; Q9B2Y3; Q9B2Z0; Q9B2Z4; Q9T6H6; Q9T9Y0; Q9TEH4;
DE   RecName: Full=Cytochrome b;
DE   AltName: Full=Complex III subunit 3;
DE   AltName: Full=Complex III subunit III;
DE   AltName: Full=Cytochrome b-c1 complex subunit 3;
DE   AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome b subunit;
GN   Name=MT-CYB; Synonyms=COB, CYTB, MTCYB;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CYC_HUMAN               Reviewed;         105 AA.
AC   P99999; A4D166; B2R4I1; P00001; Q6NUR2; Q6NX69; Q96BV4;
DE   RecName: Full=Cytochrome c;
GN   Name=CYCS; Synonyms=CYC;
DR   GO; GO:0045155; F:electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; TAS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; TAS:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0045333; P:cellular respiration; TAS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   CYFP1_HUMAN             Reviewed;        1253 AA.
AC   Q7L576; A8K6D9; Q14467; Q5IED0; Q6ZSX1; Q9BSD9; Q9BVC7;
DE   RecName: Full=Cytoplasmic FMR1-interacting protein 1;
DE   AltName: Full=Specifically Rac1-associated protein 1;
DE            Short=Sra-1;
DE   AltName: Full=p140sra-1;
GN   Name=CYFIP1; Synonyms=KIAA0068;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0048365; F:Rac GTPase binding; ISS:UniProtKB.
DR   GO; GO:0048675; P:axon extension; IMP:UniProtKB.
DR   GO; GO:0050890; P:cognition; IMP:UniProt.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IMP:UniProt.
DR   GO; GO:0016601; P:Rac protein signal transduction; IMP:UniProt.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0031529; P:ruffle organization; ISS:UniProtKB.
//
ID   CYFP2_HUMAN             Reviewed;        1278 AA.
AC   Q96F07; A6NLT2; D3DQJ3; Q53EN5; Q9NTK4; Q9ULQ2; Q9UN29;
DE   RecName: Full=Cytoplasmic FMR1-interacting protein 2;
DE   AltName: Full=p53-inducible protein 121;
GN   Name=CYFIP2; Synonyms=KIAA1168, PIR121;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
//
ID   CYGB_HUMAN              Reviewed;         190 AA.
AC   Q8WWM9; Q541Y7; Q8N2X5;
DE   RecName: Full=Cytoglobin;
DE   AltName: Full=Histoglobin;
DE            Short=HGb;
DE   AltName: Full=Stellate cell activation-associated protein;
GN   Name=CYGB; Synonyms=STAP;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; NAS:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:GOC.
DR   GO; GO:0015671; P:oxygen transport; NAS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
//
ID   CYH1_HUMAN              Reviewed;         398 AA.
AC   Q15438; A6NFW7; Q9P123; Q9P124;
DE   RecName: Full=Cytohesin-1;
DE   AltName: Full=PH, SEC7 and coiled-coil domain-containing protein 1;
DE   AltName: Full=SEC7 homolog B2-1;
GN   Name=CYTH1; Synonyms=D17S811E, PSCD1;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:Ensembl.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:MGI.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   CYH2_HUMAN              Reviewed;         400 AA.
AC   Q99418; A8K8P0; Q8IXY9; Q92958;
DE   RecName: Full=Cytohesin-2;
DE   AltName: Full=ARF exchange factor;
DE   AltName: Full=ARF nucleotide-binding site opener;
DE            Short=Protein ARNO;
DE   AltName: Full=PH, SEC7 and coiled-coil domain-containing protein 2;
GN   Name=CYTH2; Synonyms=ARNO, PSCD2, PSCD2L;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   CYH3_HUMAN              Reviewed;         400 AA.
AC   O43739; A4D2N8;
DE   RecName: Full=Cytohesin-3;
DE   AltName: Full=ARF nucleotide-binding site opener 3;
DE            Short=Protein ARNO3;
DE   AltName: Full=General receptor of phosphoinositides 1;
DE            Short=Grp1;
DE   AltName: Full=PH, SEC7 and coiled-coil domain-containing protein 3;
GN   Name=CYTH3; Synonyms=ARNO3, GRP1, PSCD3;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:Ensembl.
DR   GO; GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
//
ID   CYH4_HUMAN              Reviewed;         394 AA.
AC   Q9UIA0; Q5R3F9; Q9UGT6;
DE   RecName: Full=Cytohesin-4;
DE   AltName: Full=PH, SEC7 and coiled-coil domain-containing protein 4;
GN   Name=CYTH4; Synonyms=CYT4, PSCD4;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
//
ID   CYHR1_HUMAN             Reviewed;         362 AA.
AC   Q6ZMK1; B3KSX0; D3DWM3; Q9BSF6; Q9BSU6;
DE   RecName: Full=Cysteine and histidine-rich protein 1;
GN   Name=CYHR1; Synonyms=KIAA0496;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   CYLC1_HUMAN             Reviewed;         651 AA.
AC   P35663; A0AVQ8; Q5JQQ9;
DE   RecName: Full=Cylicin-1;
DE   AltName: Full=Cylicin I;
DE   AltName: Full=Multiple-band polypeptide I;
GN   Name=CYLC1; Synonyms=CYL, CYL1;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   CYLC2_HUMAN             Reviewed;         348 AA.
AC   Q14093; B2R8F4; Q5VVJ9;
DE   RecName: Full=Cylicin-2;
DE   AltName: Full=Cylicin II;
DE   AltName: Full=Multiple-band polypeptide II;
GN   Name=CYLC2; Synonyms=CYL2;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   CYLD_HUMAN              Reviewed;         956 AA.
AC   Q9NQC7; O94934; Q7L3N6; Q96EH0; Q9NZX9;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase CYLD;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme CYLD;
DE   AltName: Full=Ubiquitin thioesterase CYLD;
DE   AltName: Full=Ubiquitin-specific-processing protease CYLD;
GN   Name=CYLD; Synonyms=CYLD1, KIAA0849; ORFNames=HSPC057;
DR   GO; GO:0061578; F:Lys63-specific deubiquitinase activity; IDA:UniProtKB.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0070266; P:necroptotic process; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:2001242; P:regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   CYR61_HUMAN             Reviewed;         381 AA.
AC   O00622; O14934; O43775; Q9BZL7;
DE   RecName: Full=Protein CYR61;
DE   AltName: Full=CCN family member 1;
DE   AltName: Full=Cysteine-rich angiogenic inducer 61;
DE   AltName: Full=Insulin-like growth factor-binding protein 10;
DE            Short=IBP-10;
DE            Short=IGF-binding protein 10;
DE            Short=IGFBP-10;
DE   AltName: Full=Protein GIG1;
DE   Flags: Precursor;
GN   Name=CYR61; Synonyms=CCN1, GIG1, IGFBP10;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0003278; P:apoptotic process involved in heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0060591; P:chondroblast differentiation; IEA:Ensembl.
DR   GO; GO:0060710; P:chorio-allantoic fusion; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0002041; P:intussusceptive angiogenesis; IEA:Ensembl.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IGI:BHF-UCL.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:2000304; P:positive regulation of ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0010518; P:positive regulation of phospholipase activity; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
DR   GO; GO:0044319; P:wound healing, spreading of cells; IDA:BHF-UCL.
//
ID   CYS1_HUMAN              Reviewed;         158 AA.
AC   Q717R9;
DE   RecName: Full=Cystin-1;
DE   AltName: Full=Cilia-associated protein;
GN   Name=CYS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
//
ID   CYTA_HUMAN              Reviewed;          98 AA.
AC   P01040; Q6IB90;
DE   RecName: Full=Cystatin-A;
DE   AltName: Full=Cystatin-AS;
DE   AltName: Full=Stefin-A;
DE   Contains:
DE     RecName: Full=Cystatin-A, N-terminally processed;
GN   Name=CSTA; Synonyms=STF1, STFA;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:UniProt.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
//
ID   CYTB_HUMAN              Reviewed;          98 AA.
AC   P04080;
DE   RecName: Full=Cystatin-B;
DE   AltName: Full=CPI-B;
DE   AltName: Full=Liver thiol proteinase inhibitor;
DE   AltName: Full=Stefin-B;
GN   Name=CSTB; Synonyms=CST6, STFB;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:UniProt.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
//
ID   CYTC_HUMAN              Reviewed;         146 AA.
AC   P01034; B2R5J9; D3DW42; Q6FGW9;
DE   RecName: Full=Cystatin-C;
DE   AltName: Full=Cystatin-3;
DE   AltName: Full=Gamma-trace;
DE   AltName: Full=Neuroendocrine basic polypeptide;
DE   AltName: Full=Post-gamma-globulin;
DE   Flags: Precursor;
GN   Name=CST3;
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:BHF-UCL.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006952; P:defense response; IDA:BHF-UCL.
DR   GO; GO:0043206; P:extracellular fibril organization; IGI:BHF-UCL.
DR   GO; GO:0060313; P:negative regulation of blood vessel remodeling; IEP:BHF-UCL.
DR   GO; GO:0010711; P:negative regulation of collagen catabolic process; IEP:BHF-UCL.
DR   GO; GO:0060311; P:negative regulation of elastin catabolic process; IMP:BHF-UCL.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0010716; P:negative regulation of extracellular matrix disassembly; IEP:BHF-UCL.
DR   GO; GO:0010703; P:negative regulation of histolysis; IC:BHF-UCL.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:UniProt.
DR   GO; GO:0034103; P:regulation of tissue remodeling; IEP:BHF-UCL.
//
ID   CYTD_HUMAN              Reviewed;         142 AA.
AC   P28325; Q5JRF5; Q9UCA0;
DE   RecName: Full=Cystatin-D;
DE   AltName: Full=Cystatin-5;
DE   Flags: Precursor;
GN   Name=CST5;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
//
ID   CYTF_HUMAN              Reviewed;         145 AA.
AC   O76096; Q6FH95; Q7Z4J8; Q9UED4;
DE   RecName: Full=Cystatin-F;
DE   AltName: Full=Cystatin-7;
DE   AltName: Full=Cystatin-like metastasis-associated protein;
DE            Short=CMAP;
DE   AltName: Full=Leukocystatin;
DE   Flags: Precursor;
GN   Name=CST7;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   CYTIP_HUMAN             Reviewed;         359 AA.
AC   O60759; Q15630; Q8NE32;
DE   RecName: Full=Cytohesin-interacting protein;
DE   AltName: Full=Cytohesin binder and regulator;
DE            Short=CYBR;
DE   AltName: Full=Cytohesin-associated scaffolding protein;
DE            Short=CASP;
DE   AltName: Full=Cytohesin-binding protein HE;
DE            Short=Cbp HE;
DE   AltName: Full=Pleckstrin homology Sec7 and coiled-coil domains-binding protein;
GN   Name=CYTIP; Synonyms=PSCDBP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:MGI.
//
ID   CYTL1_HUMAN             Reviewed;         136 AA.
AC   Q9NRR1;
DE   RecName: Full=Cytokine-like protein 1;
DE   AltName: Full=Protein C17;
DE   Flags: Precursor;
GN   Name=CYTL1; Synonyms=C4orf4; ORFNames=UNQ1942/PRO4425;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:1990079; P:cartilage homeostasis; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050650; P:chondroitin sulfate proteoglycan biosynthetic process; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   CYTM1_HUMAN             Reviewed;          97 AA.
AC   Q9H1C7; Q8TBA5;
DE   RecName: Full=Cysteine-rich and transmembrane domain-containing protein 1;
GN   Name=CYSTM1; Synonyms=C5orf32; ORFNames=ORF1-FL49;
//
ID   CYTM_HUMAN              Reviewed;         149 AA.
AC   Q15828; Q540N7;
DE   RecName: Full=Cystatin-M;
DE   AltName: Full=Cystatin-6;
DE   AltName: Full=Cystatin-E;
DE   Flags: Precursor;
GN   Name=CST6;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   CYTN_HUMAN              Reviewed;         141 AA.
AC   P01037; Q96LE6; Q9UCQ6;
DE   RecName: Full=Cystatin-SN;
DE   AltName: Full=Cystain-SA-I;
DE   AltName: Full=Cystatin-1;
DE   AltName: Full=Salivary cystatin-SA-1;
DE   Flags: Precursor;
GN   Name=CST1;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   CYTSA_HUMAN             Reviewed;        1117 AA.
AC   Q69YQ0; B7Z758; F5H1H6; O15081;
DE   RecName: Full=Cytospin-A;
DE   AltName: Full=Renal carcinoma antigen NY-REN-22;
DE   AltName: Full=Sperm antigen with calponin homology and coiled-coil domains 1-like;
DE            Short=SPECC1-like protein;
GN   Name=SPECC1L; Synonyms=CYTSA, KIAA0376;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   CYTSB_HUMAN             Reviewed;        1068 AA.
AC   Q5M775; B4DHH0; B7WNS8; Q5IBP1; Q5IBP2; Q5IBP3; Q5IBP4; Q5M772;
AC   Q5M773; Q5M774; Q86XT8; Q8N4U4; Q8WU84; Q9HCQ3;
DE   RecName: Full=Cytospin-B;
DE   AltName: Full=Nuclear structure protein 5;
DE            Short=NSP5;
DE   AltName: Full=Sperm antigen HCMOGT-1;
DE   AltName: Full=Sperm antigen with calponin homology and coiled-coil domains 1;
GN   Name=SPECC1; Synonyms=CYTSB, NSP5;
DR   GO; GO:0007155; P:cell adhesion; IDA:MGI.
//
ID   CYTS_HUMAN              Reviewed;         141 AA.
AC   P01036; Q9UBI5; Q9UCS9;
DE   RecName: Full=Cystatin-S;
DE   AltName: Full=Cystatin-4;
DE   AltName: Full=Cystatin-SA-III;
DE   AltName: Full=Salivary acidic protein 1;
DE   Flags: Precursor;
GN   Name=CST4;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:UniProt.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:UniProt.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   CYTT_HUMAN              Reviewed;         141 AA.
AC   P09228; Q9UCQ7;
DE   RecName: Full=Cystatin-SA;
DE   AltName: Full=Cystatin-2;
DE   AltName: Full=Cystatin-S5;
DE   Flags: Precursor;
GN   Name=CST2;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   CYYR1_HUMAN             Reviewed;         154 AA.
AC   Q96J86; B2R845; Q53ER3; Q5JPD0; Q96NV7;
DE   RecName: Full=Cysteine and tyrosine-rich protein 1;
DE   AltName: Full=Proline-rich domain-containing protein;
DE   Flags: Precursor;
GN   Name=CYYR1; Synonyms=C21orf95;
//
ID   D104A_HUMAN             Reviewed;          72 AA.
AC   Q8WTQ1; Q496I2; Q496I3; Q496I4;
DE   RecName: Full=Beta-defensin 104;
DE   AltName: Full=Beta-defensin 4;
DE            Short=BD-4;
DE            Short=DEFB-4;
DE            Short=hBD-4;
DE   AltName: Full=Defensin, beta 104;
DE   Flags: Precursor;
GN   Name=DEFB104A; Synonyms=DEFB104, DEFB4;
GN   and
GN   Name=DEFB104B;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D103A_HUMAN             Reviewed;          67 AA.
AC   P81534; Q8NFG6; Q9NPF6;
DE   RecName: Full=Beta-defensin 103;
DE   AltName: Full=Beta-defensin 3;
DE            Short=BD-3;
DE            Short=DEFB-3;
DE            Short=HBD3;
DE            Short=hBD-3;
DE   AltName: Full=Defensin, beta 103;
DE   AltName: Full=Defensin-like protein;
DE   Flags: Precursor;
GN   Name=DEFB103A; Synonyms=BD3, DEFB103, DEFB3;
GN   and
GN   Name=DEFB103B;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006965; P:positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria; TAS:UniProtKB.
//
ID   D105A_HUMAN             Reviewed;          78 AA.
AC   Q8NG35; A1A581; Q8IZN8;
DE   RecName: Full=Beta-defensin 105;
DE   AltName: Full=Beta-defensin 5;
DE            Short=BD-5;
DE            Short=DEFB-5;
DE   AltName: Full=Defensin, beta 105;
DE   Flags: Precursor;
GN   Name=DEFB105A; Synonyms=BD5, DEFB105, DEFB5;
GN   and
GN   Name=DEFB105B;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D106A_HUMAN             Reviewed;          65 AA.
AC   Q8N104; Q2NKR0; Q496I8;
DE   RecName: Full=Beta-defensin 106;
DE   AltName: Full=Beta-defensin 6;
DE            Short=BD-6;
DE            Short=DEFB-6;
DE   AltName: Full=Defensin, beta 106;
DE   Flags: Precursor;
GN   Name=DEFB106A; Synonyms=BD6, DEFB106, DEFB6;
GN   and
GN   Name=DEFB106B;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D107A_HUMAN             Reviewed;          70 AA.
AC   Q8IZN7; B2RPM1; Q30E75; Q8NET2;
DE   RecName: Full=Beta-defensin 107;
DE   AltName: Full=Beta-defensin 7;
DE            Short=BD-7;
DE            Short=DEFB-7;
DE   AltName: Full=Defensin, beta 107;
DE   Flags: Precursor;
GN   Name=DEFB107A; Synonyms=DEFB107, DEFB7;
GN   and
GN   Name=DEFB107B;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D108B_HUMAN             Reviewed;          73 AA.
AC   Q8NET1;
DE   RecName: Full=Beta-defensin 108B;
DE   AltName: Full=Beta-defensin 8;
DE            Short=BD-8;
DE            Short=DEFB-8;
DE            Short=hBD-8;
DE   AltName: Full=Defensin, beta 108;
DE   AltName: Full=Defensin, beta 108B;
DE   Flags: Precursor;
GN   Name=DEFB108B; Synonyms=DEFB108, DEFB8;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D108A_HUMAN             Reviewed;          73 AA.
AC   A8MXU0;
DE   RecName: Full=Putative beta-defensin 108A;
DE   AltName: Full=Defensin, beta 108A;
DE   AltName: Full=Putative beta-defensin 108B pseudogene 1/2;
DE   Flags: Precursor;
GN   Name=DEFB108P1; Synonyms=DEFB108A;
GN   and
GN   Name=DEFB108P2;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D108C_HUMAN             Reviewed;          73 AA.
AC   A6NDD2;
DE   RecName: Full=Beta-defensin 108B-like;
DE   Flags: Precursor;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   D10OS_HUMAN             Reviewed;         163 AA.
AC   P0CZ25;
DE   RecName: Full=Uncharacterized protein DNAH10OS;
GN   Name=DNAH10OS;
//
ID   D11L8_HUMAN             Reviewed;         907 AA.
AC   A8MPP1;
DE   RecName: Full=Putative ATP-dependent RNA helicase DDX11-like protein 8;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD/H box protein 11-like 8;
GN   Name=DDX11L8;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   D19L1_HUMAN             Reviewed;         675 AA.
AC   Q2PZI1; O94954; Q4G151;
DE   RecName: Full=Probable C-mannosyltransferase DPY19L1;
DE            EC=2.4.1.-;
DE   AltName: Full=Dpy-19-like protein 1;
DE   AltName: Full=Protein dpy-19 homolog 1;
GN   Name=DPY19L1; Synonyms=GA0500, KIAA0877;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   D19L3_HUMAN             Reviewed;         716 AA.
AC   Q6ZPD9; Q68DC7; Q6ZTB7; Q6ZTS2;
DE   RecName: Full=Probable C-mannosyltransferase DPY19L3;
DE            EC=2.4.1.-;
DE   AltName: Full=Dpy-19-like protein 3;
DE   AltName: Full=Protein dpy-19 homolog 3;
GN   Name=DPY19L3;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   D19L2_HUMAN             Reviewed;         758 AA.
AC   Q6NUT2; A4FVC1; Q3ZCX2; Q6UWG8; Q96LZ9;
DE   RecName: Full=Probable C-mannosyltransferase DPY19L2;
DE            EC=2.4.1.-;
DE   AltName: Full=Dpy-19-like protein 2;
DE   AltName: Full=Protein dpy-19 homolog 2;
GN   Name=DPY19L2; ORFNames=UNQ3127/PRO10284;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IMP:UniProtKB.
//
ID   D19L4_HUMAN             Reviewed;         723 AA.
AC   Q7Z388; Q6ZW32; Q6ZW42; Q7Z329;
DE   RecName: Full=Probable C-mannosyltransferase DPY19L4;
DE            EC=2.4.1.-;
DE   AltName: Full=Dpy-19-like protein 4;
DE   AltName: Full=Protein dpy-19 homolog 4;
GN   Name=DPY19L4;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   D19P1_HUMAN             Reviewed;         242 AA.
AC   Q6NXN4; B4E2E3;
DE   RecName: Full=Putative C-mannosyltransferase DPY19L2P1;
DE            EC=2.4.1.-;
DE   AltName: Full=Dpy-19-like protein 2 pseudogene 1;
DE   AltName: Full=Protein dpy-19 homolog 2-like 1;
GN   Name=DPY19L2P1;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   D19P2_HUMAN             Reviewed;         376 AA.
AC   Q6ZN68; Q8N9V4; Q8ND62;
DE   RecName: Full=Putative C-mannosyltransferase DPY19L2P2;
DE            EC=2.4.1.-;
DE   AltName: Full=Dpy-19-like protein 2 pseudogene 2;
DE   AltName: Full=Protein dpy-19 homolog 2-like 2;
GN   Name=DPY19L2P2;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   D2HDH_HUMAN             Reviewed;         521 AA.
AC   Q8N465; B4E3L6; E7ENP2; Q6IQ24; Q8N5Q8;
DE   RecName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial;
DE            EC=1.1.99.-;
DE   Flags: Precursor;
GN   Name=D2HGDH; Synonyms=D2HGD;
DR   GO; GO:0051990; F:(R)-2-hydroxyglutarate dehydrogenase activity; ISS:HGNC.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; ISS:HGNC.
DR   GO; GO:0032025; P:response to cobalt ion; ISS:HGNC.
DR   GO; GO:0010042; P:response to manganese ion; ISS:HGNC.
DR   GO; GO:0010043; P:response to zinc ion; ISS:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   D39U1_HUMAN             Reviewed;         319 AA.
AC   Q9NRG7; Q6ZW71; Q9BVQ3;
DE   RecName: Full=Epimerase family protein SDR39U1;
DE            EC=1.1.1.-;
DE   AltName: Full=Short-chain dehydrogenase/reductase family 39U member 1;
GN   Name=SDR39U1; Synonyms=C14orf124, HCDI;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   D42E1_HUMAN             Reviewed;         393 AA.
AC   Q8WUS8; B2RDS1; Q9P0D1;
DE   RecName: Full=Short-chain dehydrogenase/reductase family 42E member 1;
DE            EC=1.1.1.-;
GN   Name=SDR42E1; ORFNames=HSPC105;
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
//
ID   D42E2_HUMAN             Reviewed;         422 AA.
AC   A6NKP2;
DE   RecName: Full=Putative short-chain dehydrogenase/reductase family 42E member 2;
DE            EC=1.1.1.-;
GN   Name=SDR42E2;
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
//
ID   DAAF1_HUMAN             Reviewed;         725 AA.
AC   Q8NEP3; B4DJA3; Q69YI8; Q69YJ0; Q69YW5; Q96LP3; Q96MB6;
DE   RecName: Full=Dynein assembly factor 1, axonemal;
DE   AltName: Full=Leucine-rich repeat-containing protein 50;
GN   Name=DNAAF1; Synonyms=LRRC50;
DR   GO; GO:0045502; F:dynein binding; IMP:UniProtKB.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0003341; P:cilium movement; IMP:BHF-UCL.
DR   GO; GO:0071907; P:determination of digestive tract left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0071910; P:determination of liver left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0035469; P:determination of pancreatic left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IC:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0036159; P:inner dynein arm assembly; IMP:BHF-UCL.
DR   GO; GO:0060972; P:left/right pattern formation; IMP:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IMP:BHF-UCL.
DR   GO; GO:0044458; P:motile cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0036158; P:outer dynein arm assembly; IMP:BHF-UCL.
DR   GO; GO:0003356; P:regulation of cilium beat frequency; IMP:BHF-UCL.
//
ID   DAAF3_HUMAN             Reviewed;         541 AA.
AC   Q8N9W5; A8MUY0; E9PAX5; Q6P4F6; Q8N9W0; Q96AR2;
DE   RecName: Full=Dynein assembly factor 3, axonemal;
GN   Name=DNAAF3; Synonyms=C19orf51;
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.
DR   GO; GO:0044458; P:motile cilium assembly; IMP:UniProtKB.
//
ID   DAAM1_HUMAN             Reviewed;        1078 AA.
AC   Q9Y4D1; Q86U34; Q8N1Z8; Q8TB39;
DE   RecName: Full=Disheveled-associated activator of morphogenesis 1;
GN   Name=DAAM1; Synonyms=KIAA0666;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
//
ID   DAAM2_HUMAN             Reviewed;        1068 AA.
AC   Q86T65; G5EA45; Q5T4T8; Q5T4U0; Q9NQI5; Q9Y4G0;
DE   RecName: Full=Disheveled-associated activator of morphogenesis 2;
GN   Name=DAAM2; Synonyms=KIAA0381;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
//
ID   DAB1_HUMAN              Reviewed;         588 AA.
AC   O75553; A4FU90; B3KTG3; Q4LE59; Q5T6M6; Q5T6M9; Q5T835; Q5T836;
AC   Q5T837; Q6NWS9; Q6NWT0; Q6NWT1; Q9NYA8;
DE   RecName: Full=Disabled homolog 1;
GN   Name=DAB1;
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0021813; P:cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration; IEA:Ensembl.
DR   GO; GO:0021589; P:cerebellum structural organization; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0051645; P:Golgi localization; IEA:Ensembl.
DR   GO; GO:0097477; P:lateral motor column neuron migration; IEA:Ensembl.
DR   GO; GO:0007494; P:midgut development; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0021942; P:radial glia guided migration of Purkinje cell; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0021517; P:ventral spinal cord development; IEA:Ensembl.
//
ID   DAB2P_HUMAN             Reviewed;        1189 AA.
AC   Q5VWQ8; A6H8V2; A6NHI9; B0QZB1; G3XA90; Q8TDL2; Q96SE1; Q9C0C0;
DE   RecName: Full=Disabled homolog 2-interacting protein;
DE            Short=DAB2 interaction protein;
DE            Short=DAB2-interacting protein;
DE   AltName: Full=ASK-interacting protein 1;
DE            Short=AIP-1;
DE   AltName: Full=DOC-2/DAB-2 interactive protein;
GN   Name=DAB2IP; Synonyms=AF9Q34, AIP1, KIAA1743;
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:BHF-UCL.
DR   GO; GO:0005123; F:death receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:UniProtKB.
DR   GO; GO:0036312; F:phosphatidylinositol 3-kinase regulatory subunit binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:BHF-UCL.
DR   GO; GO:0005099; F:Ras GTPase activator activity; ISS:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IDA:UniProtKB.
DR   GO; GO:0035591; F:signaling adaptor activity; IDA:BHF-UCL.
DR   GO; GO:0043184; F:vascular endothelial growth factor receptor 2 binding; IPI:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0021814; P:cell motility involved in cerebral cortex radial glia guided migration; ISS:UniProtKB.
DR   GO; GO:0044257; P:cellular protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0072577; P:endothelial cell apoptotic process; TAS:BHF-UCL.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:BHF-UCL.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; ISS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; ISS:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000599; P:negative regulation of cyclin catabolic process; IDA:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0070317; P:negative regulation of G0 to G1 transition; IDA:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; ISS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0043553; P:negative regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0034261; P:negative regulation of Ras GTPase activity; IMP:BHF-UCL.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IC:BHF-UCL.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:1900747; P:negative regulation of vascular endothelial growth factor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:1900006; P:positive regulation of dendrite development; ISS:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:2001224; P:positive regulation of neuron migration; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:1901800; P:positive regulation of proteasomal protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; ISS:UniProtKB.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:1900744; P:regulation of p38MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0006927; P:transformed cell apoptotic process; TAS:BHF-UCL.
DR   GO; GO:0035148; P:tube formation; IMP:UniProtKB.
DR   GO; GO:0036324; P:vascular endothelial growth factor receptor-2 signaling pathway; ISS:UniProtKB.
//
ID   DAB2_HUMAN              Reviewed;         770 AA.
AC   P98082; A6NES5; Q13598; Q9BTY0; Q9UK04;
DE   RecName: Full=Disabled homolog 2;
DE   AltName: Full=DOC-2;
DE   AltName: Full=Differentially-expressed protein 2;
GN   Name=DAB2; Synonyms=DOC2;
DR   GO; GO:0038024; F:cargo receptor activity; IMP:UniProtKB.
DR   GO; GO:0035615; F:clathrin adaptor activity; IMP:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000904; P:cell morphogenesis involved in differentiation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0030099; P:myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0006907; P:pinocytosis; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:2000370; P:positive regulation of clathrin-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:2000643; P:positive regulation of early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IMP:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:2001046; P:positive regulation of integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IEA:Ensembl.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000096; P:positive regulation of Wnt signaling pathway, planar cell polarity pathway; IMP:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DACH1_HUMAN             Reviewed;         760 AA.
AC   Q9UI36; D0FY35; D0FY36; O75523; O75687; Q5VYY3; Q5VYY4; Q96SG3;
AC   Q96SG4; Q9H524; Q9UMH4;
DE   RecName: Full=Dachshund homolog 1;
DE            Short=Dach1;
GN   Name=DACH1; Synonyms=DACH;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001075; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0046545; P:development of primary female sexual characteristics; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IMP:BHF-UCL.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
//
ID   DACH2_HUMAN             Reviewed;         599 AA.
AC   Q96NX9; B1AJV3; B4DQG3; Q8NAY3; Q8ND17; Q96N55;
DE   RecName: Full=Dachshund homolog 2;
DE            Short=Dach2;
GN   Name=DACH2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046545; P:development of primary female sexual characteristics; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DACT1_HUMAN             Reviewed;         836 AA.
AC   Q9NYF0; A8MYJ2; Q86TY0;
DE   RecName: Full=Dapper homolog 1;
DE            Short=hDPR1;
DE   AltName: Full=Dapper antagonist of catenin 1;
DE   AltName: Full=Hepatocellular carcinoma novel gene 3 protein;
GN   Name=DACT1; Synonyms=DPR1, HNG3;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0070097; F:delta-catenin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; IDA:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0048619; P:embryonic hindgut morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IMP:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035412; P:regulation of catenin import into nucleus; IMP:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IDA:UniProtKB.
DR   GO; GO:2000095; P:regulation of Wnt signaling pathway, planar cell polarity pathway; ISS:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DACT3_HUMAN             Reviewed;         629 AA.
AC   Q96B18;
DE   RecName: Full=Dapper homolog 3;
DE   AltName: Full=Antagonist of beta-catenin Dapper homolog 3;
DE   AltName: Full=Arginine-rich region 1 protein;
DE   AltName: Full=Dapper antagonist of catenin 3;
GN   Name=DACT3; Synonyms=RRR1;
DR   GO; GO:0070097; F:delta-catenin binding; ISS:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; ISS:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:UniProtKB.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DAD1_HUMAN              Reviewed;         113 AA.
AC   P61803; D3DS25; O08552; O70364; P46966; P46968; Q6FGA3; Q96GB7;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1;
DE            Short=Oligosaccharyl transferase subunit DAD1;
DE            EC=2.4.99.18;
DE   AltName: Full=Defender against cell death 1;
DE            Short=DAD-1;
GN   Name=DAD1;
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; ISS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IC:HGNC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   DACT2_HUMAN             Reviewed;         774 AA.
AC   Q5SW24; Q2NKJ2; Q569G0; Q8WYW2;
DE   RecName: Full=Dapper homolog 2;
DE   AltName: Full=Dapper antagonist of catenin 2;
GN   Name=DACT2; Synonyms=C6orf116; ORFNames=PP13671;
DR   GO; GO:0008013; F:beta-catenin binding; ISS:UniProtKB.
DR   GO; GO:0070097; F:delta-catenin binding; ISS:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; ISS:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072061; P:inner medullary collecting duct development; ISS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:1900108; P:negative regulation of nodal signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043588; P:skin development; ISS:UniProtKB.
//
ID   DAF_HUMAN               Reviewed;         381 AA.
AC   P08174; B1AP14; D3DT83; D3DT84; E7ER69; P09679; P78361; Q14UF2;
AC   Q14UF3; Q14UF4; Q14UF5; Q14UF6;
DE   RecName: Full=Complement decay-accelerating factor;
DE   AltName: CD_antigen=CD55;
DE   Flags: Precursor;
GN   Name=CD55; Synonyms=CR, DAF;
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0001618; F:virus receptor activity; IDA:UniProt.
DR   GO; GO:0035743; P:CD4-positive, alpha-beta T cell cytokine production; IDA:UniProt.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0045916; P:negative regulation of complement activation; IDA:UniProt.
DR   GO; GO:2000516; P:positive regulation of CD4-positive, alpha-beta T cell activation; IDA:UniProt.
DR   GO; GO:2000563; P:positive regulation of CD4-positive, alpha-beta T cell proliferation; IDA:UniProt.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
DR   GO; GO:0031664; P:regulation of lipopolysaccharide-mediated signaling pathway; IDA:UniProt.
DR   GO; GO:0045730; P:respiratory burst; NAS:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IDA:GOC.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   DAG1_HUMAN              Reviewed;         895 AA.
AC   Q14118; A8K6M7; Q969J9;
DE   RecName: Full=Dystroglycan;
DE   AltName: Full=Dystrophin-associated glycoprotein 1;
DE   Contains:
DE     RecName: Full=Alpha-dystroglycan;
DE              Short=Alpha-DG;
DE   Contains:
DE     RecName: Full=Beta-dystroglycan;
DE              Short=Beta-DG;
DE   Flags: Precursor;
GN   Name=DAG1;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0051393; F:alpha-actinin binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0043237; F:laminin-1 binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0071711; P:basement membrane organization; IEA:Ensembl.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0016340; P:calcium-dependent cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0071679; P:commissural neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; IMP:UniProtKB.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; IMP:UniProtKB.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; IDA:UniProtKB.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0021682; P:nerve maturation; IEA:Ensembl.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
//
ID   DALD3_HUMAN             Reviewed;         543 AA.
AC   Q5D0E6; Q7Z5S7; Q86WY1; Q8N105; Q8NA89; Q9NVU8;
DE   RecName: Full=DALR anticodon-binding domain-containing protein 3;
GN   Name=DALRD3;
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
//
ID   DAND5_HUMAN             Reviewed;         189 AA.
AC   Q8N907;
DE   RecName: Full=DAN domain family member 5;
DE   AltName: Full=Cerberus-like protein 2;
DE            Short=Cerl-2;
DE   AltName: Full=Cysteine knot superfamily 1, BMP antagonist 3;
DE   AltName: Full=Gremlin-3;
DE   Flags: Precursor;
GN   Name=DAND5; Synonyms=CER2, CKTSF1B3, GREM3, SP1;
DR   GO; GO:0016015; F:morphogen activity; ISS:BHF-UCL.
DR   GO; GO:0003283; P:atrial septum development; ISS:BHF-UCL.
DR   GO; GO:0061371; P:determination of heart left/right asymmetry; ISS:BHF-UCL.
DR   GO; GO:0003140; P:determination of left/right asymmetry in lateral mesoderm; ISS:BHF-UCL.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:1900108; P:negative regulation of nodal signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0038101; P:sequestering of nodal from receptor via nodal binding; ISS:BHF-UCL.
DR   GO; GO:0003281; P:ventricular septum development; ISS:BHF-UCL.
//
ID   DANCR_HUMAN             Reviewed;         163 AA.
AC   P0C864;
DE   RecName: Full=Putative uncharacterized protein DANCR;
DE   AltName: Full=Anti-differentiation ncRNA protein;
DE   AltName: Full=Differentiation antagonizing non-protein coding RNA;
DE   AltName: Full=Small nucleolar RNA host gene protein 13;
GN   Name=DANCR; Synonyms=ANCR, KIAA0114, SNHG13;
//
ID   DAOA_HUMAN              Reviewed;         153 AA.
AC   P59103; A6NKG7; Q0VAE6; Q5VX59; Q86Y17; Q8IWM4;
DE   RecName: Full=D-amino acid oxidase activator;
DE   AltName: Full=Protein G72;
GN   Name=DAOA; Synonyms=G72;
DR   GO; GO:0008047; F:enzyme activator activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:1900758; P:negative regulation of D-amino-acid oxidase activity; IDA:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:UniProtKB.
//
ID   DAP1_HUMAN              Reviewed;         102 AA.
AC   P51397; Q6FGC3; Q9BUC9;
DE   RecName: Full=Death-associated protein 1;
DE            Short=DAP-1;
GN   Name=DAP; Synonyms=DAP1;
DR   GO; GO:0070513; F:death domain binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IGI:MGI.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0034198; P:cellular response to amino acid starvation; IDA:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
//
ID   DAPK1_HUMAN             Reviewed;        1430 AA.
AC   P53355; B7ZLD2; B7ZLE7; Q14CQ7; Q1W5W0; Q68CP8; Q6ZRZ3; Q9BTL8;
DE   RecName: Full=Death-associated protein kinase 1;
DE            Short=DAP kinase 1;
DE            EC=2.7.11.1;
GN   Name=DAPK1; Synonyms=DAPK;
DR   GuidetoPHARMACOLOGY; 2002; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   DAPK2_HUMAN             Reviewed;         370 AA.
AC   Q9UIK4; E9JGM7; O75892; Q24JS1;
DE   RecName: Full=Death-associated protein kinase 2;
DE            Short=DAP kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=DAP-kinase-related protein 1;
DE            Short=DRP-1;
GN   Name=DAPK2;
DR   GuidetoPHARMACOLOGY; 2003; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IBA:RefGenome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0043276; P:anoikis; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:2001242; P:regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
//
ID   DAPK3_HUMAN             Reviewed;         454 AA.
AC   O43293; A0AVN4; B3KQE2; Q05JY4;
DE   RecName: Full=Death-associated protein kinase 3;
DE            Short=DAP kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=DAP-like kinase;
DE            Short=Dlk;
DE   AltName: Full=MYPT1 kinase;
DE   AltName: Full=Zipper-interacting protein kinase;
DE            Short=ZIP-kinase;
GN   Name=DAPK3; Synonyms=ZIPK;
DR   GuidetoPHARMACOLOGY; 2004; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IBA:RefGenome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000910; P:cytokinesis; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; TAS:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:UniProtKB.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DAPLE_HUMAN             Reviewed;        2028 AA.
AC   Q9P219; Q69YK1; Q7L1M2; Q86SX7; Q8IYG8;
DE   RecName: Full=Protein Daple;
DE   AltName: Full=Coiled-coil domain-containing protein 88C;
DE   AltName: Full=Dvl-associating protein with a high frequency of leucine residues;
DE            Short=hDaple;
DE   AltName: Full=Hook-related protein 2;
DE            Short=HkRP2;
GN   Name=CCDC88C; Synonyms=DAPLE, KIAA1509;
DR   GO; GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; ISS:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DAPL1_HUMAN             Reviewed;         107 AA.
AC   A0PJW8; A0PJW9; B9EIK6;
DE   RecName: Full=Death-associated protein-like 1;
DE   AltName: Full=Early epithelial differentiation-associated protein;
GN   Name=DAPL1; Synonyms=EEDA;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   DAPP1_HUMAN             Reviewed;         280 AA.
AC   Q9UN19; Q8TCK5; Q9UHF2;
DE   RecName: Full=Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;
DE            Short=hDAPP1;
DE   AltName: Full=B lymphocyte adapter protein Bam32;
DE   AltName: Full=B-cell adapter molecule of 32 kDa;
GN   Name=DAPP1; Synonyms=BAM32; ORFNames=HSPC066;
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; NAS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   DAS1_HUMAN              Reviewed;         148 AA.
AC   A6NH13;
DE   RecName: Full=Putative uncharacterized protein DNAJC9-AS1;
DE   AltName: Full=DNAJC9 antisense RNA 1;
DE   AltName: Full=DNAJC9 antisense gene protein 1;
GN   Name=DNAJC9-AS1; Synonyms=C10orf103;
//
ID   DAW1_HUMAN              Reviewed;         415 AA.
AC   Q8N136; Q6ZRY1; Q8N776;
DE   RecName: Full=Dynein assembly factor with WDR repeat domains 1;
DE   AltName: Full=Outer row dynein assembly protein 16 homolog;
DE   AltName: Full=WD repeat-containing protein 69;
GN   Name=DAW1; Synonyms=WDR69;
//
ID   DAXX_HUMAN              Reviewed;         740 AA.
AC   Q9UER7; B4E1I3; F5H082; O14747; O15141; O15208; Q5STK9; Q9BWI3;
DE   RecName: Full=Death domain-associated protein 6;
DE   AltName: Full=Daxx;
DE            Short=hDaxx;
DE   AltName: Full=ETS1-associated protein 1;
DE            Short=EAP1;
DE   AltName: Full=Fas death domain-associated protein;
GN   Name=DAXX; Synonyms=BING2, DAP6;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0031072; F:heat shock protein binding; TAS:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:ProtInc.
DR   GO; GO:0000281; P:mitotic cytokinesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DAZ1_HUMAN              Reviewed;         744 AA.
AC   Q9NQZ3; Q9NQZ4;
DE   RecName: Full=Deleted in azoospermia protein 1;
GN   Name=DAZ1; Synonyms=DAZ, SPGY;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008494; F:translation activator activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   DAZ2_HUMAN              Reviewed;         558 AA.
AC   Q13117; Q2KHN6; Q96P41; Q9NR91;
DE   RecName: Full=Deleted in azoospermia protein 2;
GN   Name=DAZ2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   DAZ4_HUMAN              Reviewed;         579 AA.
AC   Q86SG3; Q9NR88; Q9NR89;
DE   RecName: Full=Deleted in azoospermia protein 4;
GN   Name=DAZ4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   DAZ3_HUMAN              Reviewed;         486 AA.
AC   Q9NR90; Q2KHN7;
DE   RecName: Full=Deleted in azoospermia protein 3;
GN   Name=DAZ3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   DAZL_HUMAN              Reviewed;         295 AA.
AC   Q92904; O15396; Q5HYB4; Q92909;
DE   RecName: Full=Deleted in azoospermia-like;
DE   AltName: Full=DAZ homolog;
DE   AltName: Full=DAZ-like autosomal;
DE   AltName: Full=Deleted in azoospermia-like 1;
DE   AltName: Full=SPGY-like-autosomal;
GN   Name=DAZL; Synonyms=DAZH, DAZL1, DAZLA, SPGYLA;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008494; F:translation activator activity; IDA:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045836; P:positive regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   DAZP1_HUMAN             Reviewed;         407 AA.
AC   Q96EP5; Q96MJ3; Q9NRR9;
DE   RecName: Full=DAZ-associated protein 1;
DE   AltName: Full=Deleted in azoospermia-associated protein 1;
GN   Name=DAZAP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0035613; F:RNA stem-loop binding; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   DAZP2_HUMAN             Reviewed;         168 AA.
AC   Q15038; A8K254; B4DDT5; B4E1G3; C9JA96; C9JP84; F8VU62;
DE   RecName: Full=DAZ-associated protein 2;
DE   AltName: Full=Deleted in azoospermia-associated protein 2;
GN   Name=DAZAP2; Synonyms=KIAA0058;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
//
ID   DB109_HUMAN             Reviewed;          87 AA.
AC   Q30KR1;
DE   RecName: Full=Beta-defensin 109;
DE   AltName: Full=Defensin, beta 109;
DE   AltName: Full=Defensin, beta 109, pseudogene 1/1B;
DE   Flags: Precursor;
GN   Name=DEFB109P1; Synonyms=DEFB109, DEFB109A;
GN   and
GN   Name=DEFB109P1B;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB110_HUMAN             Reviewed;          67 AA.
AC   Q30KQ9; Q30KR0;
DE   RecName: Full=Beta-defensin 110;
DE   AltName: Full=Beta-defensin 10;
DE            Short=DEFB-10;
DE   AltName: Full=Beta-defensin 11;
DE            Short=DEFB-11;
DE   AltName: Full=Beta-defensin 111;
DE   AltName: Full=Defensin, beta 110;
DE   AltName: Full=Defensin, beta 111;
DE   Flags: Precursor;
GN   Name=DEFB110; Synonyms=DEFB10, DEFB11, DEFB111;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB112_HUMAN             Reviewed;         113 AA.
AC   Q30KQ8; Q8NET0;
DE   RecName: Full=Beta-defensin 112;
DE   AltName: Full=Beta-defensin 12;
DE            Short=DEFB-12;
DE   AltName: Full=Defensin, beta 112;
DE   Flags: Precursor;
GN   Name=DEFB112; Synonyms=DEFB12;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB113_HUMAN             Reviewed;          82 AA.
AC   Q30KQ7;
DE   RecName: Full=Beta-defensin 113;
DE   AltName: Full=Beta-defensin 13;
DE            Short=DEFB-13;
DE   AltName: Full=Defensin, beta 113;
DE   Flags: Precursor;
GN   Name=DEFB113; Synonyms=DEFB13;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB114_HUMAN             Reviewed;          69 AA.
AC   Q30KQ6; Q8NES9;
DE   RecName: Full=Beta-defensin 114;
DE   AltName: Full=Beta-defensin 14;
DE            Short=DEFB-14;
DE   AltName: Full=Defensin, beta 114;
DE   Flags: Precursor;
GN   Name=DEFB114; Synonyms=DEFB14;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
//
ID   DB115_HUMAN             Reviewed;          88 AA.
AC   Q30KQ5;
DE   RecName: Full=Beta-defensin 115;
DE   AltName: Full=Beta-defensin 15;
DE            Short=DEFB-15;
DE   AltName: Full=Defensin, beta 115;
DE   Flags: Precursor;
GN   Name=DEFB115; Synonyms=DEFB15;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB116_HUMAN             Reviewed;         102 AA.
AC   Q30KQ4;
DE   RecName: Full=Beta-defensin 116;
DE   AltName: Full=Beta-defensin 16;
DE            Short=DEFB-16;
DE   AltName: Full=Defensin, beta 116;
DE   Flags: Precursor;
GN   Name=DEFB116; Synonyms=DEFB16;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB118_HUMAN             Reviewed;         123 AA.
AC   Q96PH6; Q17RC4; Q8N691; Q9NUH0;
DE   RecName: Full=Beta-defensin 118;
DE   AltName: Full=Beta-defensin 18;
DE            Short=DEFB-18;
DE   AltName: Full=Defensin, beta 118;
DE   AltName: Full=Epididymal secretory protein 13.6;
DE            Short=ESP13.6;
DE   Flags: Precursor;
GN   Name=DEFB118; Synonyms=C20orf63, DEFB18, ESC42;
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   DB119_HUMAN             Reviewed;          84 AA.
AC   Q8N690; Q5GRG1; Q5JWP1; Q5TH42; Q8N689;
DE   RecName: Full=Beta-defensin 119;
DE   AltName: Full=Beta-defensin 120;
DE   AltName: Full=Beta-defensin 19;
DE            Short=DEFB-19;
DE   AltName: Full=Beta-defensin 20;
DE            Short=DEFB-20;
DE   AltName: Full=Defensin, beta 119;
DE   AltName: Full=Defensin, beta 120;
DE   AltName: Full=ESC42-RELA;
DE   Flags: Precursor;
GN   Name=DEFB119; Synonyms=DEFB120, DEFB19, DEFB20;
GN   ORFNames=UNQ2449/PRO5729;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB121_HUMAN             Reviewed;          76 AA.
AC   Q5J5C9; A1L4N1;
DE   RecName: Full=Beta-defensin 121;
DE   AltName: Full=Beta-defensin 21;
DE            Short=DEFB-21;
DE   AltName: Full=Defensin, beta 121;
DE   Flags: Precursor;
GN   Name=DEFB121; Synonyms=DEFB21;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB123_HUMAN             Reviewed;          67 AA.
AC   Q8N688;
DE   RecName: Full=Beta-defensin 123;
DE   AltName: Full=Beta-defensin 23;
DE            Short=DEFB-23;
DE   AltName: Full=Defensin, beta 123;
DE   Flags: Precursor;
GN   Name=DEFB123; Synonyms=DEFB23; ORFNames=UNQ1963/PRO4485;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB124_HUMAN             Reviewed;          71 AA.
AC   Q8NES8; Q30E74;
DE   RecName: Full=Beta-defensin 124;
DE   AltName: Full=Beta-defensin 24;
DE            Short=DEFB-24;
DE   AltName: Full=Defensin, beta 124;
DE   Flags: Precursor;
GN   Name=DEFB124; Synonyms=DEFB24;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB125_HUMAN             Reviewed;         156 AA.
AC   Q8N687; A1A502; Q7Z7B9;
DE   RecName: Full=Beta-defensin 125;
DE   AltName: Full=Beta-defensin 25;
DE            Short=DEFB-25;
DE   AltName: Full=Defensin, beta 125;
DE   Flags: Precursor;
GN   Name=DEFB125; Synonyms=DEFB25;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB126_HUMAN             Reviewed;         111 AA.
AC   Q9BYW3; Q562G3; Q9H1M5;
DE   RecName: Full=Beta-defensin 126;
DE   AltName: Full=Beta-defensin 26;
DE            Short=DEFB-26;
DE   AltName: Full=Defensin, beta 126;
DE   AltName: Full=Epididymal secretory protein 13.2;
DE            Short=ESP13.2;
DE   Flags: Precursor;
GN   Name=DEFB126; Synonyms=C20orf8, DEFB26;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB127_HUMAN             Reviewed;          99 AA.
AC   Q9H1M4; Q14DW7;
DE   RecName: Full=Beta-defensin 127;
DE   AltName: Full=Beta-defensin 27;
DE            Short=DEFB-27;
DE   AltName: Full=Defensin, beta 127;
DE   Flags: Precursor;
GN   Name=DEFB127; Synonyms=C20orf73, DEFB27; ORFNames=UNQ1956/PRO6071;
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
//
ID   DB128_HUMAN             Reviewed;          93 AA.
AC   Q7Z7B8; B2RU29;
DE   RecName: Full=Beta-defensin 128;
DE   AltName: Full=Beta-defensin 28;
DE            Short=DEFB-28;
DE   AltName: Full=Defensin, beta 128;
DE   Flags: Precursor;
GN   Name=DEFB128; Synonyms=DEFB28;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB129_HUMAN             Reviewed;         183 AA.
AC   Q9H1M3; Q8NES7;
DE   RecName: Full=Beta-defensin 129;
DE   AltName: Full=Beta-defensin 29;
DE            Short=DEFB-29;
DE   AltName: Full=Defensin, beta 129;
DE   Flags: Precursor;
GN   Name=DEFB129; Synonyms=C20orf87, DEFB29; ORFNames=UNQ5794/PRO19599;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB130_HUMAN             Reviewed;          79 AA.
AC   Q30KQ2;
DE   RecName: Full=Beta-defensin 130;
DE   AltName: Full=Beta-defensin 30;
DE            Short=DEFB-30;
DE   AltName: Full=Defensin, beta 130;
DE   Flags: Precursor;
GN   Name=DEFB130; Synonyms=DEFB30;
GN   and
GN   Name=DEFB130L;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB131_HUMAN             Reviewed;          70 AA.
AC   P59861;
DE   RecName: Full=Beta-defensin 131;
DE   AltName: Full=Beta-defensin 31;
DE            Short=DEFB-31;
DE   AltName: Full=Defensin, beta 131;
DE   Flags: Precursor;
GN   Name=DEFB131; Synonyms=DEFB31;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB132_HUMAN             Reviewed;          95 AA.
AC   Q7Z7B7; B2RP72; Q4QY40;
DE   RecName: Full=Beta-defensin 132;
DE   AltName: Full=Beta-defensin 32;
DE            Short=BD-32;
DE            Short=DEFB-32;
DE   AltName: Full=Defensin HEL-75;
DE   AltName: Full=Defensin, beta 132;
DE   Flags: Precursor;
GN   Name=DEFB132; Synonyms=DEFB32; ORFNames=UNQ827/PRO1754;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB133_HUMAN             Reviewed;          61 AA.
AC   Q30KQ1; Q4QY39;
DE   RecName: Full=Beta-defensin 133;
DE   AltName: Full=Defensin, beta 133;
DE   Flags: Precursor;
GN   Name=DEFB133;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB134_HUMAN             Reviewed;          66 AA.
AC   Q4QY38; A1L4A4;
DE   RecName: Full=Beta-defensin 134;
DE   AltName: Full=Defensin, beta 134;
DE   Flags: Precursor;
GN   Name=DEFB134;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB135_HUMAN             Reviewed;          77 AA.
AC   Q30KP9; Q4QY37;
DE   RecName: Full=Beta-defensin 135;
DE   AltName: Full=Defensin, beta 135;
DE   Flags: Precursor;
GN   Name=DEFB135;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DB136_HUMAN             Reviewed;          78 AA.
AC   Q30KP8; Q4QY36;
DE   RecName: Full=Beta-defensin 136;
DE   AltName: Full=Defensin, beta 136;
DE   Flags: Precursor;
GN   Name=DEFB136;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   DBF4A_HUMAN             Reviewed;         674 AA.
AC   Q9UBU7; A4D1D8; A8K954; O75226; Q75MS6; Q75N01; Q9Y2M6;
DE   RecName: Full=Protein DBF4 homolog A;
DE   AltName: Full=Activator of S phase kinase;
DE   AltName: Full=Chiffon homolog A;
DE   AltName: Full=DBF4-type zinc finger-containing protein 1;
GN   Name=DBF4; Synonyms=ASK, DBF4A, ZDBF1;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
//
ID   DBF4B_HUMAN             Reviewed;         615 AA.
AC   Q8NFT6; D3DX56; Q8TEX0; Q96B19; Q9H912;
DE   RecName: Full=Protein DBF4 homolog B;
DE   AltName: Full=Activator of S phase kinase-like protein 1;
DE            Short=ASK-like protein 1;
DE   AltName: Full=Chiffon homolog B;
DE   AltName: Full=Dbf4-related factor 1;
GN   Name=DBF4B; Synonyms=ASKL1, DRF1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:UniProt.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:GOC.
//
ID   DBLOH_HUMAN             Reviewed;         239 AA.
AC   Q9NR28; B2RDQ0; Q6W3F3; Q96LV0; Q9BT11; Q9HAV6;
DE   RecName: Full=Diablo homolog, mitochondrial;
DE   AltName: Full=Direct IAP-binding protein with low pI;
DE   AltName: Full=Second mitochondria-derived activator of caspase;
DE            Short=Smac;
DE   Flags: Precursor;
GN   Name=DIABLO; Synonyms=SMAC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:UniProtKB.
DR   GO; GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:ProtInc.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:UniProtKB.
//
ID   DBND1_HUMAN             Reviewed;         158 AA.
AC   Q9H9R9; B4DQS3; Q69YT2; Q9BW25;
DE   RecName: Full=Dysbindin domain-containing protein 1;
GN   Name=DBNDD1;
//
ID   DBND2_HUMAN             Reviewed;         259 AA.
AC   Q9BQY9; Q331S6; Q5QPV4; Q5QPV6; Q9BQZ0; Q9BVL1; Q9H1F6; Q9NWZ0;
AC   Q9NY07; Q9NZ31;
DE   RecName: Full=Dysbindin domain-containing protein 2;
DE   AltName: Full=Casein kinase-1 binding protein;
DE            Short=CK1BP;
DE   AltName: Full=HSMNP1;
GN   Name=DBNDD2; Synonyms=C20orf35;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
//
ID   DBNL_HUMAN              Reviewed;         430 AA.
AC   Q9UJU6; A4D2I9; B4DEM2; C9J7P1; P84070; Q6IAI8; Q96F30; Q96K74;
AC   Q9HBN8; Q9NR72;
DE   RecName: Full=Drebrin-like protein;
DE   AltName: Full=Cervical SH3P7;
DE   AltName: Full=Cervical mucin-associated protein;
DE   AltName: Full=Drebrin-F;
DE   AltName: Full=HPK1-interacting protein of 55 kDa;
DE            Short=HIP-55;
DE   AltName: Full=SH3 domain-containing protein 7;
GN   Name=DBNL; Synonyms=CMAP, SH3P7; ORFNames=PP5423;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0071800; P:podosome assembly; ISS:UniProtKB.
DR   GO; GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0007416; P:synapse assembly; ISS:UniProtKB.
//
ID   DBP_HUMAN               Reviewed;         325 AA.
AC   Q10586; A2I2P4;
DE   RecName: Full=D site-binding protein;
DE   AltName: Full=Albumin D box-binding protein;
DE   AltName: Full=Albumin D-element-binding protein;
DE   AltName: Full=Tax-responsive enhancer element-binding protein 302;
DE            Short=TaxREB302;
GN   Name=DBP;
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
//
ID   DBR1_HUMAN              Reviewed;         544 AA.
AC   Q9UK59; Q96GH0; Q9NXQ6;
DE   RecName: Full=Lariat debranching enzyme;
DE            EC=3.1.-.-;
GN   Name=DBR1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008419; F:RNA lariat debranching enzyme activity; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IMP:GOC.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; IMP:UniProtKB.
//
ID   DBX1_HUMAN              Reviewed;         343 AA.
AC   A6NMT0;
DE   RecName: Full=Homeobox protein DBX1;
DE   AltName: Full=Developing brain homeobox protein 1;
GN   Name=DBX1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   DBX2_HUMAN              Reviewed;         339 AA.
AC   Q6ZNG2;
DE   RecName: Full=Homeobox protein DBX2;
DE   AltName: Full=Developing brain homeobox protein 2;
GN   Name=DBX2;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
//
ID   DC121_HUMAN             Reviewed;         463 AA.
AC   Q5VU92; Q8IYK3;
DE   RecName: Full=DDB1- and CUL4-associated factor 12-like protein 1;
DE   AltName: Full=WD repeat-containing protein 40B;
GN   Name=DCAF12L1; Synonyms=WDR40B;
//
ID   DC122_HUMAN             Reviewed;         463 AA.
AC   Q5VW00; B2RN42;
DE   RecName: Full=DDB1- and CUL4-associated factor 12-like protein 2;
DE   AltName: Full=WD repeat-containing protein 40C;
GN   Name=DCAF12L2; Synonyms=WDR40C;
//
ID   DC1I1_HUMAN             Reviewed;         645 AA.
AC   O14576; B4DME3; F5H050; G5E9K1; Q8TBF7; Q9Y2X1;
DE   RecName: Full=Cytoplasmic dynein 1 intermediate chain 1;
DE   AltName: Full=Cytoplasmic dynein intermediate chain 1;
DE   AltName: Full=Dynein intermediate chain 1, cytosolic;
DE            Short=DH IC-1;
GN   Name=DYNC1I1; Synonyms=DNCI1, DNCIC1;
DR   GO; GO:0008017; F:microtubule binding; ISS:HGNC.
DR   GO; GO:0003777; F:microtubule motor activity; ISS:HGNC.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0047496; P:vesicle transport along microtubule; ISS:HGNC.
//
ID   DC1I2_HUMAN             Reviewed;         638 AA.
AC   Q13409; B7ZA04; D3DPD4; D3DPD5; D3DPD6; Q32LY9; Q53S84; Q5BJF8;
AC   Q7Z4X1; Q96NG7; Q96S87; Q9BXZ5; Q9NT58;
DE   RecName: Full=Cytoplasmic dynein 1 intermediate chain 2;
DE   AltName: Full=Cytoplasmic dynein intermediate chain 2;
DE   AltName: Full=Dynein intermediate chain 2, cytosolic;
DE            Short=DH IC-2;
GN   Name=DYNC1I2; Synonyms=DNCI2, DNCIC2;
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DC1L1_HUMAN             Reviewed;         523 AA.
AC   Q9Y6G9; A2RRG7; Q53HC8; Q53HK7;
DE   RecName: Full=Cytoplasmic dynein 1 light intermediate chain 1;
DE            Short=LIC1;
DE   AltName: Full=Dynein light chain A;
DE            Short=DLC-A;
DE   AltName: Full=Dynein light intermediate chain 1, cytosolic;
GN   Name=DYNC1LI1; Synonyms=DNCLI1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DC1L2_HUMAN             Reviewed;         492 AA.
AC   O43237; A8K6V1; B4DZP4; Q8TAT3;
DE   RecName: Full=Cytoplasmic dynein 1 light intermediate chain 2;
DE   AltName: Full=Dynein light intermediate chain 2, cytosolic;
DE            Short=LIC-2;
DE   AltName: Full=LIC53/55;
GN   Name=DYNC1LI2; Synonyms=DNCLI2, LIC2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DC2L1_HUMAN             Reviewed;         351 AA.
AC   Q8TCX1; A8MVJ5; Q53F57; Q6PDB2; Q8IWA3; Q96B03; Q96J00; Q9Y370;
AC   Q9Y3S9;
DE   RecName: Full=Cytoplasmic dynein 2 light intermediate chain 1;
DE            Short=Dynein 2 light intermediate chain;
GN   Name=DYNC2LI1; Synonyms=D2LIC, LIC3; ORFNames=CGI-60;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
//
ID   DC4L2_HUMAN             Reviewed;         395 AA.
AC   Q8NA75;
DE   RecName: Full=DDB1- and CUL4-associated factor 4-like protein 2;
DE   AltName: Full=WD repeat-containing protein 21C;
GN   Name=DCAF4L2; Synonyms=WDR21C;
//
ID   DC8L1_HUMAN             Reviewed;         600 AA.
AC   A6NGE4; B3KXX1;
DE   RecName: Full=DDB1- and CUL4-associated factor 8-like protein 1;
DE   AltName: Full=WD repeat-containing protein 42B;
GN   Name=DCAF8L1; Synonyms=WDR42B;
//
ID   DC8L2_HUMAN             Reviewed;         631 AA.
AC   P0C7V8; B2RXH9; J3KT06;
DE   RecName: Full=DDB1- and CUL4-associated factor 8-like protein 2;
DE   AltName: Full=WD repeat-containing protein 42C;
GN   Name=DCAF8L2; Synonyms=WDR42C;
//
ID   DC4L1_HUMAN             Reviewed;         396 AA.
AC   Q3SXM0; B3KVI3; Q3ZCW8; Q499Y5; Q9UFI0;
DE   RecName: Full=DDB1- and CUL4-associated factor 4-like protein 1;
DE   AltName: Full=WD repeat-containing protein 21B;
GN   Name=DCAF4L1; Synonyms=WDR21B;
//
ID   DCA10_HUMAN             Reviewed;         559 AA.
AC   Q5QP82; A4VCJ5; Q32NE2; Q8N2Q5; Q96ET5; Q9BTQ5; Q9H5P6;
DE   RecName: Full=DDB1- and CUL4-associated factor 10;
DE   AltName: Full=WD repeat-containing protein 32;
GN   Name=DCAF10; Synonyms=WDR32;
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCA11_HUMAN             Reviewed;         546 AA.
AC   Q8TEB1; B3KQ83; D3DS56; Q5D039; Q86U00; Q86U39; Q8NDN2; Q9H2J0;
AC   Q9H3A3; Q9H5C9;
DE   RecName: Full=DDB1- and CUL4-associated factor 11;
DE   AltName: Full=WD repeat-containing protein 23;
GN   Name=DCAF11; Synonyms=WDR23; ORFNames=GL014, PRO2389;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCA12_HUMAN             Reviewed;         453 AA.
AC   Q5T6F0; A8KA70; D3DRL6; Q5T6E9; Q5T6F1; Q6P3V0; Q7L4F8; Q96PZ5;
AC   Q9NXA9; Q9UFJ1;
DE   RecName: Full=DDB1- and CUL4-associated factor 12;
DE   AltName: Full=Centrosome-related protein TCC52;
DE   AltName: Full=Testis cancer centrosome-related protein;
DE   AltName: Full=WD repeat-containing protein 40A;
GN   Name=DCAF12; Synonyms=KIAA1892, TCC52, WDR40A;
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCA13_HUMAN             Reviewed;         445 AA.
AC   Q9NV06; Q3MII9; Q8NCH8; Q8TC51; Q96JY7; Q9NZX3;
DE   RecName: Full=DDB1- and CUL4-associated factor 13;
DE   AltName: Full=WD repeat and SOF domain-containing protein 1;
GN   Name=DCAF13; Synonyms=WDSOF1; ORFNames=HSPC064;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   DCA15_HUMAN             Reviewed;         600 AA.
AC   Q66K64; B3KS86; Q96DW0; Q9BU31;
DE   RecName: Full=DDB1- and CUL4-associated factor 15;
GN   Name=DCAF15; Synonyms=C19orf72;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   DCA16_HUMAN             Reviewed;         216 AA.
AC   Q9NXF7; B3KPB7;
DE   RecName: Full=DDB1- and CUL4-associated factor 16;
GN   Name=DCAF16; Synonyms=C4orf30;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCA17_HUMAN             Reviewed;         520 AA.
AC   Q5H9S7; B2RTW5; Q53TN3; Q9H908;
DE   RecName: Full=DDB1- and CUL4-associated factor 17;
GN   Name=DCAF17; Synonyms=C2orf37;
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCAF4_HUMAN             Reviewed;         495 AA.
AC   Q8WV16; B4DUT6; G3V522; Q86U31; Q8IV10; Q96K22; Q9Y4P5;
DE   RecName: Full=DDB1- and CUL4-associated factor 4;
DE   AltName: Full=WD repeat-containing protein 21A;
GN   Name=DCAF4; Synonyms=WDR21, WDR21A;
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCAF5_HUMAN             Reviewed;         942 AA.
AC   Q96JK2; B2RN31; O60559; Q8N3V3; Q8N3V5;
DE   RecName: Full=DDB1- and CUL4-associated factor 5;
DE   AltName: Full=Breakpoint cluster region protein 2;
DE            Short=BCRP2;
DE   AltName: Full=WD repeat-containing protein 22;
GN   Name=DCAF5; Synonyms=BCRG2, KIAA1824, WDR22;
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCAF6_HUMAN             Reviewed;         860 AA.
AC   Q58WW2; A2A295; B4DNB8; Q7L8I0; Q8IXH3; Q8TB19;
DE   RecName: Full=DDB1- and CUL4-associated factor 6;
DE   AltName: Full=Androgen receptor complex-associated protein;
DE            Short=ARCAP;
DE   AltName: Full=IQ motif and WD repeat-containing protein 1;
DE   AltName: Full=Nuclear receptor interaction protein;
DE            Short=NRIP;
GN   Name=DCAF6; Synonyms=IQWD1; ORFNames=MSTP055;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCAF7_HUMAN             Reviewed;         342 AA.
AC   P61962; B4E039; D3DU14; O15491; Q9DAE4;
DE   RecName: Full=DDB1- and CUL4-associated factor 7;
DE   AltName: Full=WD repeat-containing protein 68;
DE   AltName: Full=WD repeat-containing protein An11 homolog;
GN   Name=DCAF7; Synonyms=HAN11, WDR68;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCAF8_HUMAN             Reviewed;         597 AA.
AC   Q5TAQ9; D3DVE6; Q12839; Q4QQI6; Q53F14; Q66K50; Q68CS7; Q96E00;
DE   RecName: Full=DDB1- and CUL4-associated factor 8;
DE   AltName: Full=WD repeat-containing protein 42A;
GN   Name=DCAF8; Synonyms=H326, WDR42A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IC:UniProtKB.
//
ID   DCAKD_HUMAN             Reviewed;         231 AA.
AC   Q8WVC6; A8K3Z0; D3DX60; D3DX62; Q9BR71; Q9H5W1;
DE   RecName: Full=Dephospho-CoA kinase domain-containing protein;
GN   Name=DCAKD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:InterPro.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.
//
ID   DCAM_HUMAN              Reviewed;         334 AA.
AC   P17707; E1P5F7; Q5VXN4; Q5VXN6; Q9BWK4;
DE   RecName: Full=S-adenosylmethionine decarboxylase proenzyme;
DE            Short=AdoMetDC;
DE            Short=SAMDC;
DE            EC=4.1.1.50;
DE   Contains:
DE     RecName: Full=S-adenosylmethionine decarboxylase alpha chain;
DE   Contains:
DE     RecName: Full=S-adenosylmethionine decarboxylase beta chain;
DE   Flags: Precursor;
GN   Name=AMD1; Synonyms=AMD;
DR   GO; GO:0004014; F:adenosylmethionine decarboxylase activity; TAS:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0006557; P:S-adenosylmethioninamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006597; P:spermine biosynthetic process; IEA:InterPro.
//
ID   DCBD1_HUMAN             Reviewed;         715 AA.
AC   Q8N8Z6; Q5H992; Q8IYK5; Q8N7L9; Q96NH2;
DE   RecName: Full=Discoidin, CUB and LCCL domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=DCBLD1;
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   DCBD2_HUMAN             Reviewed;         775 AA.
AC   Q96PD2; B7WNL1; D3DN41; Q8N6M4; Q8TDX2;
DE   RecName: Full=Discoidin, CUB and LCCL domain-containing protein 2;
DE   AltName: Full=CUB, LCCL and coagulation factor V/VIII-homology domains protein 1;
DE   AltName: Full=Endothelial and smooth muscle cell-derived neuropilin-like protein;
DE   Flags: Precursor;
GN   Name=DCBLD2; Synonyms=CLCP1, ESDN;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IDA:UniProtKB.
//
ID   DCC1_HUMAN              Reviewed;         393 AA.
AC   Q9BVC3; Q969N5;
DE   RecName: Full=Sister chromatid cohesion protein DCC1;
DE   AltName: Full=Defective in sister chromatid cohesion protein 1 homolog;
GN   Name=DSCC1; Synonyms=DCC1; ORFNames=UNQ9337/PRO34008;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0034421; P:post-translational protein acetylation; IMP:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; IMP:UniProtKB.
//
ID   DCC_HUMAN               Reviewed;        1447 AA.
AC   P43146;
DE   RecName: Full=Netrin receptor DCC;
DE   AltName: Full=Colorectal cancer suppressor;
DE   AltName: Full=Immunoglobulin superfamily DCC subclass member 1;
DE   AltName: Full=Tumor suppressor protein DCC;
DE   Flags: Precursor;
GN   Name=DCC; Synonyms=IGDCC1;
DR   GO; GO:0005042; F:netrin receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0033564; P:anterior/posterior axon guidance; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007409; P:axonogenesis; TAS:ProtInc.
DR   GO; GO:0033563; P:dorsal/ventral axon guidance; IEA:Ensembl.
DR   GO; GO:0048671; P:negative regulation of collateral sprouting; TAS:BHF-UCL.
DR   GO; GO:2000171; P:negative regulation of dendrite development; TAS:BHF-UCL.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; TAS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0021965; P:spinal cord ventral commissure morphogenesis; IEA:Ensembl.
//
ID   DCD2B_HUMAN             Reviewed;         349 AA.
AC   A2VCK2; B7ZBC6;
DE   RecName: Full=Doublecortin domain-containing protein 2B;
GN   Name=DCDC2B;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DCD2C_HUMAN             Reviewed;         355 AA.
AC   A8MYV0;
DE   RecName: Full=Doublecortin domain-containing protein 2C;
GN   Name=DCDC2C;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DCDC1_HUMAN             Reviewed;         354 AA.
AC   P59894; A6PVL6;
DE   RecName: Full=Doublecortin domain-containing protein 1;
GN   Name=DCDC1;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DCDC2_HUMAN             Reviewed;         476 AA.
AC   Q9UHG0; Q5VTR8; Q5VTR9; Q86W35; Q9UFD1; Q9UHG1; Q9ULR6;
DE   RecName: Full=Doublecortin domain-containing protein 2;
DE   AltName: Full=Protein RU2S;
GN   Name=DCDC2; Synonyms=KIAA1154, RU2;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
//
ID   DCDC5_HUMAN             Reviewed;         648 AA.
AC   Q6ZRR9; B1AL47;
DE   RecName: Full=Doublecortin domain-containing protein 5;
GN   Name=DCDC5; Synonyms=KIAA1493;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DCD_HUMAN               Reviewed;         110 AA.
AC   P81605; A5JHP2; A5JHP3; P58461; Q53YJ2;
DE   RecName: Full=Dermcidin;
DE            EC=3.4.-.-;
DE   AltName: Full=Preproteolysin;
DE   Contains:
DE     RecName: Full=Survival-promoting peptide;
DE   Contains:
DE     RecName: Full=DCD-1;
DE   Flags: Precursor;
GN   Name=DCD; Synonyms=AIDD, DSEP;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   DCE1_HUMAN              Reviewed;         594 AA.
AC   Q99259; Q49AK1; Q53TQ7; Q9BU91; Q9UHH4;
DE   RecName: Full=Glutamate decarboxylase 1;
DE            EC=4.1.1.15;
DE   AltName: Full=67 kDa glutamic acid decarboxylase;
DE            Short=GAD-67;
DE   AltName: Full=Glutamate decarboxylase 67 kDa isoform;
GN   Name=GAD1; Synonyms=GAD, GAD67;
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   GO; GO:0009449; P:gamma-aminobutyric acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006538; P:glutamate catabolic process; TAS:UniProtKB.
DR   GO; GO:0006540; P:glutamate decarboxylation to succinate; TAS:ProtInc.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0018352; P:protein-pyridoxal-5-phosphate linkage; TAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   DCE2_HUMAN              Reviewed;         585 AA.
AC   Q05329; Q9UD87;
DE   RecName: Full=Glutamate decarboxylase 2;
DE            EC=4.1.1.15;
DE   AltName: Full=65 kDa glutamic acid decarboxylase;
DE            Short=GAD-65;
DE   AltName: Full=Glutamate decarboxylase 65 kDa isoform;
GN   Name=GAD2; Synonyms=GAD65;
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:Ensembl.
DR   GO; GO:0006540; P:glutamate decarboxylation to succinate; TAS:ProtInc.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   DCHS_HUMAN              Reviewed;         662 AA.
AC   P19113; A1L4G0;
DE   RecName: Full=Histidine decarboxylase;
DE            Short=HDC;
DE            EC=4.1.1.22;
GN   Name=HDC;
DR   GuidetoPHARMACOLOGY; 1274; -.
DR   GO; GO:0004398; F:histidine decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0042423; P:catecholamine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0001694; P:histamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006548; P:histidine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006547; P:histidine metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DCK_HUMAN               Reviewed;         260 AA.
AC   P27707; B2R8V6; Q5TZY7; Q6FI11;
DE   RecName: Full=Deoxycytidine kinase;
DE            Short=dCK;
DE            EC=2.7.1.74;
GN   Name=DCK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004137; F:deoxycytidine kinase activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0009157; P:deoxyribonucleoside monophosphate biosynthetic process; IDA:GOC.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; EXP:GOC.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0006220; P:pyrimidine nucleotide metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DCLK1_HUMAN             Reviewed;         740 AA.
AC   O15075; B7Z3E9; Q5VZY8; Q5VZZ0; Q5VZZ1;
DE   RecName: Full=Serine/threonine-protein kinase DCLK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Doublecortin domain-containing protein 3A;
DE   AltName: Full=Doublecortin-like and CAM kinase-like 1;
DE   AltName: Full=Doublecortin-like kinase 1;
GN   Name=DCLK1; Synonyms=DCAMKL1, DCDC3A, KIAA0369;
DR   GuidetoPHARMACOLOGY; 2005; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0016197; P:endosomal transport; NAS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   DCLK2_HUMAN             Reviewed;         766 AA.
AC   Q8N568; C9J5Q9; Q59GC8; Q8N399;
DE   RecName: Full=Serine/threonine-protein kinase DCLK2;
DE            EC=2.7.11.1;
DE   AltName: Full=CaMK-like CREB regulatory kinase 2;
DE            Short=CL2;
DE            Short=CLICK-II;
DE            Short=CLICK2;
DE   AltName: Full=Doublecortin domain-containing protein 3B;
DE   AltName: Full=Doublecortin-like and CAM kinase-like 2;
DE   AltName: Full=Doublecortin-like kinase 2;
GN   Name=DCLK2; Synonyms=DCAMKL2, DCDC3B, DCK2;
DR   GuidetoPHARMACOLOGY; 2006; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DCLK3_HUMAN             Reviewed;         648 AA.
AC   Q9C098;
DE   RecName: Full=Serine/threonine-protein kinase DCLK3;
DE            EC=2.7.11.1;
DE   AltName: Full=Doublecortin domain-containing protein 3C;
DE   AltName: Full=Doublecortin-like and CAM kinase-like 3;
DE   AltName: Full=Doublecortin-like kinase 3;
GN   Name=DCLK3; Synonyms=DCAMKL3, DCDC3C, KIAA1765;
DR   GuidetoPHARMACOLOGY; 2007; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   DCMC_HUMAN              Reviewed;         493 AA.
AC   O95822; Q9UNU5; Q9Y3F2;
DE   RecName: Full=Malonyl-CoA decarboxylase, mitochondrial;
DE            Short=MCD;
DE            EC=4.1.1.9;
DE   Flags: Precursor;
GN   Name=MLYCD;
DR   GO; GO:0050080; F:malonyl-CoA decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006085; P:acetyl-CoA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2001294; P:malonyl-CoA catabolic process; IDA:UniProtKB.
DR   GO; GO:0046321; P:positive regulation of fatty acid oxidation; IMP:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IMP:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DCNL3_HUMAN             Reviewed;         304 AA.
AC   Q8IWE4; B3KVY4;
DE   RecName: Full=DCN1-like protein 3;
DE   AltName: Full=DCUN1 domain-containing protein 3;
DE   AltName: Full=Defective in cullin neddylation protein 1-like protein 3;
GN   Name=DCUN1D3;
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0010225; P:response to UV-C; IDA:UniProtKB.
//
ID   DCNL2_HUMAN             Reviewed;         259 AA.
AC   Q6PH85; Q5JSA5; Q5JSA6; Q5JSA7; Q9NVJ1; Q9NXR6;
DE   RecName: Full=DCN1-like protein 2;
DE   AltName: Full=DCUN1 domain-containing protein 2;
DE   AltName: Full=Defective in cullin neddylation protein 1-like protein 2;
GN   Name=DCUN1D2; Synonyms=C13orf17, DCUN1L2;
//
ID   DCNL1_HUMAN             Reviewed;         259 AA.
AC   Q96GG9; B2RB37; Q7L3G9; Q8TEX7; Q9H6M1; Q9HCT3;
DE   RecName: Full=DCN1-like protein 1;
DE   AltName: Full=DCUN1 domain-containing protein 1;
DE   AltName: Full=Defective in cullin neddylation protein 1-like protein 1;
DE   AltName: Full=Squamous cell carcinoma-related oncogene;
GN   Name=DCUN1D1; Synonyms=DCUN1L1, RP42, SCCRO;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   DCNL4_HUMAN             Reviewed;         292 AA.
AC   Q92564; B4DH25; Q7Z3F3; Q7Z6B8;
DE   RecName: Full=DCN1-like protein 4;
DE   AltName: Full=DCUN1 domain-containing protein 4;
DE   AltName: Full=Defective in cullin neddylation protein 1-like protein 4;
GN   Name=DCUN1D4; Synonyms=KIAA0276;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   DCNL5_HUMAN             Reviewed;         237 AA.
AC   Q9BTE7; Q3ZTT2;
DE   RecName: Full=DCN1-like protein 5;
DE   AltName: Full=DCUN1 domain-containing protein 5;
DE   AltName: Full=Defective in cullin neddylation protein 1-like protein 5;
GN   Name=DCUN1D5;
//
ID   DCNP1_HUMAN             Reviewed;         244 AA.
AC   Q8TF63;
DE   RecName: Full=Dendritic cell nuclear protein 1;
GN   Name=DCNP1; Synonyms=C5orf20;
//
ID   DCOR_HUMAN              Reviewed;         461 AA.
AC   P11926; Q53TU3; Q6LDS9;
DE   RecName: Full=Ornithine decarboxylase;
DE            Short=ODC;
DE            EC=4.1.1.17;
GN   Name=ODC1;
DR   GuidetoPHARMACOLOGY; 1276; -.
DR   GO; GO:0004586; F:ornithine decarboxylase activity; TAS:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0033387; P:putrescine biosynthetic process from ornithine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DCP1A_HUMAN             Reviewed;         582 AA.
AC   Q9NPI6;
DE   RecName: Full=mRNA-decapping enzyme 1A;
DE            EC=3.-.-.-;
DE   AltName: Full=Smad4-interacting transcriptional co-activator;
DE   AltName: Full=Transcription factor SMIF;
GN   Name=DCP1A; Synonyms=SMIF;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   DCP1B_HUMAN             Reviewed;         617 AA.
AC   Q8IZD4; Q86XH9; Q96BP8; Q96MZ8;
DE   RecName: Full=mRNA-decapping enzyme 1B;
DE            EC=3.-.-.-;
GN   Name=DCP1B;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   DCP2_HUMAN              Reviewed;         420 AA.
AC   Q8IU60; C9J778; Q6P2D4; Q7Z5W5; Q8NBG5;
DE   RecName: Full=m7GpppN-mRNA hydrolase;
DE            EC=3.6.1.62;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 20;
DE            Short=Nudix motif 20;
DE   AltName: Full=mRNA-decapping enzyme 2;
DE            Short=hDpc;
GN   Name=DCP2; Synonyms=NUDT20;
DR   GO; GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; TAS:Reactome.
DR   GO; GO:0050072; F:m7G(5')pppN diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; TAS:GOC.
//
ID   DCPS_HUMAN              Reviewed;         337 AA.
AC   Q96C86; Q8NHL8; Q9Y2S5;
DE   RecName: Full=m7GpppX diphosphatase;
DE            EC=3.6.1.59;
DE   AltName: Full=DCS-1;
DE   AltName: Full=Decapping scavenger enzyme;
DE   AltName: Full=Hint-related 7meGMP-directed hydrolase;
DE   AltName: Full=Histidine triad nucleotide-binding protein 5;
DE   AltName: Full=Histidine triad protein member 5;
DE            Short=HINT-5;
DE   AltName: Full=Scavenger mRNA-decapping enzyme DcpS;
GN   Name=DCPS; Synonyms=DCS1, HINT5; ORFNames=HSPC015;
DR   GO; GO:0050072; F:m7G(5')pppN diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000340; F:RNA 7-methylguanosine cap binding; IDA:UniProtKB.
DR   GO; GO:0036245; P:cellular response to menadione; IDA:UniProtKB.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IDA:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   DCR1A_HUMAN             Reviewed;        1040 AA.
AC   Q6PJP8; D3DRC1; Q14701; Q6P5Y3; Q6PKL4;
DE   RecName: Full=DNA cross-link repair 1A protein;
DE   AltName: Full=SNM1 homolog A;
DE            Short=hSNM1;
DE            Short=hSNM1A;
GN   Name=DCLRE1A; Synonyms=KIAA0086, SNM1, SNM1A;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:Ensembl.
//
ID   DCR1B_HUMAN             Reviewed;         532 AA.
AC   Q9H816; Q9H9E5;
DE   RecName: Full=5' exonuclease Apollo;
DE            EC=3.1.-.-;
DE   AltName: Full=DNA cross-link repair 1B protein;
DE   AltName: Full=SNM1 homolog B;
DE            Short=SNMIB;
DE            Short=hSNM1B;
GN   Name=DCLRE1B; Synonyms=SNM1B;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0031848; P:protection from non-homologous end joining at telomere; IMP:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0031860; P:telomeric 3' overhang formation; ISS:UniProtKB.
DR   GO; GO:0031627; P:telomeric loop formation; ISS:UniProtKB.
//
ID   DCR1C_HUMAN             Reviewed;         692 AA.
AC   Q96SD1; D3DRT6; Q1HCL2; Q5JSR4; Q5JSR5; Q5JSR7; Q5JSR8; Q5JSR9;
AC   Q5JSS0; Q5JSS7; Q6PK14; Q8N101; Q8N132; Q8TBW9; Q9BVW9; Q9HAM4;
DE   RecName: Full=Protein artemis;
DE            EC=3.1.-.-;
DE   AltName: Full=DNA cross-link repair 1C protein;
DE   AltName: Full=Protein A-SCID;
DE   AltName: Full=SNM1 homolog C;
DE            Short=hSNM1C;
DE   AltName: Full=SNM1-like protein;
GN   Name=DCLRE1C; Synonyms=ARTEMIS, ASCID, SCIDA, SNM1C;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IDA:MGI.
DR   GO; GO:0000014; F:single-stranded DNA endodeoxyribonuclease activity; IDA:MGI.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; IEA:Ensembl.
//
ID   DCST1_HUMAN             Reviewed;         706 AA.
AC   Q5T197; B4DXA0; E9PHV3; Q5T198; Q6P1W6; Q71S70; Q96M70;
DE   RecName: Full=DC-STAMP domain-containing protein 1;
GN   Name=DCST1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   DCST2_HUMAN             Reviewed;         773 AA.
AC   Q5T1A1; Q2M2R2; Q8N810; Q96M03;
DE   RecName: Full=DC-STAMP domain-containing protein 2;
GN   Name=DCST2;
//
ID   DCSTP_HUMAN             Reviewed;         470 AA.
AC   Q9H295; B7ZVW2; E7ESG0; Q2M2D5;
DE   RecName: Full=Dendritic cell-specific transmembrane protein;
DE            Short=DC-STAMP;
DE            Short=hDC-STAMP;
DE   AltName: Full=Dendrocyte-expressed seven transmembrane protein;
DE   AltName: Full=IL-four-induced protein;
DE            Short=FIND;
DE   AltName: Full=Transmembrane 7 superfamily member 4;
GN   Name=DCSTAMP; Synonyms=TM7SF4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IDA:UniProtKB.
DR   GO; GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; ISS:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; ISS:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0072675; P:osteoclast fusion; ISS:UniProtKB.
DR   GO; GO:0045780; P:positive regulation of bone resorption; ISS:UniProtKB.
DR   GO; GO:0034241; P:positive regulation of macrophage fusion; ISS:UniProtKB.
DR   GO; GO:0045657; P:positive regulation of monocyte differentiation; ISS:UniProtKB.
//
ID   DCTD_HUMAN              Reviewed;         178 AA.
AC   P32321; B2R836; D3DP49; D3DP50; Q5M7Z8; Q9BVD8;
DE   RecName: Full=Deoxycytidylate deaminase;
DE            EC=3.5.4.12;
DE   AltName: Full=dCMP deaminase;
GN   Name=DCTD;
DR   GO; GO:0004132; F:dCMP deaminase activity; EXP:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
DR   GO; GO:0006220; P:pyrimidine nucleotide metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DCTN1_HUMAN             Reviewed;        1278 AA.
AC   Q14203; A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; O95296; Q6IQ37;
AC   Q9BRM9; Q9UIU1; Q9UIU2;
DE   RecName: Full=Dynactin subunit 1;
DE   AltName: Full=150 kDa dynein-associated polypeptide;
DE   AltName: Full=DAP-150;
DE            Short=DP-150;
DE   AltName: Full=p135;
DE   AltName: Full=p150-glued;
GN   Name=DCTN1;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; NAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DCTN2_HUMAN             Reviewed;         401 AA.
AC   Q13561; B2RBK5; Q86YN2; Q9BW17;
DE   RecName: Full=Dynactin subunit 2;
DE   AltName: Full=50 kDa dynein-associated polypeptide;
DE   AltName: Full=Dynactin complex 50 kDa subunit;
DE            Short=DCTN-50;
DE   AltName: Full=p50 dynamitin;
GN   Name=DCTN2; Synonyms=DCTN50;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007052; P:mitotic spindle organization; IEA:Ensembl.
//
ID   DCTN3_HUMAN             Reviewed;         186 AA.
AC   O75935; A6NII7; B2RBM5; Q5T1I5; Q5T1I7; Q5T8G3; Q9BPU8;
DE   RecName: Full=Dynactin subunit 3;
DE   AltName: Full=Dynactin complex subunit 22 kDa subunit;
DE            Short=p22;
GN   Name=DCTN3; Synonyms=DCTN22;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   DCTN4_HUMAN             Reviewed;         460 AA.
AC   Q9UJW0; B3KWW0; D3DQH0; E5RGT5; Q8TAN8;
DE   RecName: Full=Dynactin subunit 4;
DE            Short=Dyn4;
DE   AltName: Full=Dynactin subunit p62;
GN   Name=DCTN4;
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
//
ID   DCTN5_HUMAN             Reviewed;         182 AA.
AC   Q9BTE1; A8K9X8; H3BN51; H3BQA4;
DE   RecName: Full=Dynactin subunit 5;
DE   AltName: Full=Dynactin subunit p25;
GN   Name=DCTN5;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
//
ID   DCTN6_HUMAN             Reviewed;         190 AA.
AC   O00399; B2RAC1;
DE   RecName: Full=Dynactin subunit 6;
DE   AltName: Full=Dynactin subunit p27;
DE   AltName: Full=Protein WS-3;
GN   Name=DCTN6; Synonyms=WS3;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
//
ID   DCTP1_HUMAN             Reviewed;         170 AA.
AC   Q9H773;
DE   RecName: Full=dCTP pyrophosphatase 1;
DE            EC=3.6.1.12;
DE   AltName: Full=Deoxycytidine-triphosphatase 1;
DE            Short=dCTPase 1;
DE   AltName: Full=RS21C6;
DE   AltName: Full=XTP3-transactivated gene A protein;
GN   Name=DCTPP1; Synonyms=XTP3TPA; ORFNames=CDA03;
DR   GO; GO:0047840; F:dCTP diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0047429; F:nucleoside-triphosphate diphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0032556; F:pyrimidine deoxyribonucleotide binding; IEA:Ensembl.
DR   GO; GO:0009143; P:nucleoside triphosphate catabolic process; ISS:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
//
ID   DCUP_HUMAN              Reviewed;         367 AA.
AC   P06132; A8K762; Q16863; Q16883; Q53YB8; Q53ZP6; Q6IB28; Q9BUZ0;
DE   RecName: Full=Uroporphyrinogen decarboxylase;
DE            Short=UPD;
DE            Short=URO-D;
DE            EC=4.1.1.37;
GN   Name=UROD;
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0006783; P:heme biosynthetic process; IC:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DCXR_HUMAN              Reviewed;         244 AA.
AC   Q7Z4W1; Q9BTZ3; Q9UHY9;
DE   RecName: Full=L-xylulose reductase;
DE            Short=XR;
DE            EC=1.1.1.10;
DE   AltName: Full=Carbonyl reductase II;
DE   AltName: Full=Dicarbonyl/L-xylulose reductase;
DE   AltName: Full=Kidney dicarbonyl reductase;
DE            Short=kiDCR;
DE   AltName: Full=Sperm surface protein P34H;
GN   Name=DCXR;
DR   GO; GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006006; P:glucose metabolic process; IDA:UniProtKB.
DR   GO; GO:0006739; P:NADP metabolic process; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
//
ID   DCX_HUMAN               Reviewed;         441 AA.
AC   O43602; A6NFY6; A9Z1V8; D3DUY8; D3DUY9; D3DUZ0; O43911; Q5JYZ5;
DE   RecName: Full=Neuronal migration protein doublecortin;
DE   AltName: Full=Doublin;
DE   AltName: Full=Lissencephalin-X;
DE            Short=Lis-X;
GN   Name=DCX; Synonyms=DBCN, LISX;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001764; P:neuron migration; IDA:UniProtKB.
//
ID   DD19A_HUMAN             Reviewed;         478 AA.
AC   Q9NUU7; B2RPL0; Q53FM0;
DE   RecName: Full=ATP-dependent RNA helicase DDX19A;
DE            EC=3.6.4.13;
DE   AltName: Full=DDX19-like protein;
DE   AltName: Full=DEAD box protein 19A;
GN   Name=DDX19A; Synonyms=DDX19L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
//
ID   DD19B_HUMAN             Reviewed;         479 AA.
AC   Q9UMR2; B3KNE9; B4DXS6; E7EMK4; Q6FIB7; Q6IAE0; Q96KE7; Q9H0U0;
DE   RecName: Full=ATP-dependent RNA helicase DDX19B;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box RNA helicase DEAD5;
DE   AltName: Full=DEAD box protein 19B;
GN   Name=DDX19B; Synonyms=DBP5, DDX19, TDBP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DDA1_HUMAN              Reviewed;         102 AA.
AC   Q9BW61;
DE   RecName: Full=DET1- and DDB1-associated protein 1;
DE   AltName: Full=Placenta cross-immune reaction antigen 1;
DE            Short=PCIA-1;
GN   Name=DDA1; Synonyms=C19orf58, PCIA1;
//
ID   DDAH1_HUMAN             Reviewed;         285 AA.
AC   O94760; Q5HYC8; Q86XK5;
DE   RecName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 1;
DE            Short=DDAH-1;
DE            Short=Dimethylarginine dimethylaminohydrolase 1;
DE            EC=3.5.3.18;
DE   AltName: Full=DDAHI;
DE   AltName: Full=Dimethylargininase-1;
GN   Name=DDAH1; Synonyms=DDAH;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0016403; F:dimethylargininase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006527; P:arginine catabolic process; TAS:ProtInc.
DR   GO; GO:0000052; P:citrulline metabolic process; IDA:UniProtKB.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL.
//
ID   DDAH2_HUMAN             Reviewed;         285 AA.
AC   O95865; A2BEZ7;
DE   RecName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 2;
DE            Short=DDAH-2;
DE            Short=Dimethylarginine dimethylaminohydrolase 2;
DE            EC=3.5.3.18;
DE   AltName: Full=DDAHII;
DE   AltName: Full=Dimethylargininase-2;
DE   AltName: Full=Protein G6a;
DE   AltName: Full=S-phase protein;
GN   Name=DDAH2; Synonyms=DDAH, G6A, NG30;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0016403; F:dimethylargininase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006527; P:arginine catabolic process; TAS:ProtInc.
DR   GO; GO:0000052; P:citrulline metabolic process; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:BHF-UCL.
//
ID   DDB1_HUMAN              Reviewed;        1140 AA.
AC   Q16531; A6NG77; B2R648; O15176; Q13289; Q58F96;
DE   RecName: Full=DNA damage-binding protein 1;
DE   AltName: Full=DDB p127 subunit;
DE   AltName: Full=DNA damage-binding protein a;
DE            Short=DDBa;
DE   AltName: Full=Damage-specific DNA-binding protein 1;
DE   AltName: Full=HBV X-associated protein 1;
DE            Short=XAP-1;
DE   AltName: Full=UV-damaged DNA-binding factor;
DE   AltName: Full=UV-damaged DNA-binding protein 1;
DE            Short=UV-DDB 1;
DE   AltName: Full=XPE-binding factor;
DE            Short=XPE-BF;
DE   AltName: Full=Xeroderma pigmentosum group E-complementing protein;
DE            Short=XPCe;
GN   Name=DDB1; Synonyms=XAP1;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProt.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:1901990; P:regulation of mitotic cell cycle phase transition; IMP:UniProtKB.
DR   GO; GO:0070914; P:UV-damage excision repair; IDA:UniProt.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   DDB2_HUMAN              Reviewed;         427 AA.
AC   Q92466; B2R875; Q76E54; Q76E55; Q76E56; Q76E57;
DE   RecName: Full=DNA damage-binding protein 2;
DE   AltName: Full=DDB p48 subunit;
DE            Short=DDBb;
DE   AltName: Full=Damage-specific DNA-binding protein 2;
DE   AltName: Full=UV-damaged DNA-binding protein 2;
DE            Short=UV-DDB 2;
GN   Name=DDB2;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProt.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0070914; P:UV-damage excision repair; IDA:UniProt.
//
ID   DDC8_HUMAN              Reviewed;         621 AA.
AC   Q96MC4;
DE   RecName: Full=Protein DDC8 homolog;
GN   Name=DDC8;
//
ID   DDC_HUMAN               Reviewed;         480 AA.
AC   P20711; C9IYA0; E7ER62; E7EU95; Q16723; Q5W5T9; Q75MJ6;
DE   RecName: Full=Aromatic-L-amino-acid decarboxylase;
DE            Short=AADC;
DE            EC=4.1.1.28;
DE   AltName: Full=DOPA decarboxylase;
DE            Short=DDC;
GN   Name=DDC; Synonyms=AADC;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0004058; F:aromatic-L-amino-acid decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0042423; P:catecholamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071312; P:cellular response to alkaloid; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046219; P:indolalkylamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0033076; P:isoquinoline alkaloid metabolic process; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0052314; P:phytoalexin metabolic process; IEA:Ensembl.
DR   GO; GO:0046684; P:response to pyrethroid; IEA:Ensembl.
DR   GO; GO:0042427; P:serotonin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0015842; P:synaptic vesicle amine transport; IEA:Ensembl.
//
ID   DDHD1_HUMAN             Reviewed;         900 AA.
AC   Q8NEL9; G5E9D1; Q8WVH3; Q96LL2; Q9C0F8;
DE   RecName: Full=Phospholipase DDHD1;
DE            EC=3.1.1.-;
DE   AltName: Full=DDHD domain-containing protein 1;
DE   AltName: Full=Phosphatidic acid-preferring phospholipase A1 homolog;
DE            Short=PA-PLA1;
GN   Name=DDHD1; Synonyms=KIAA1705;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   DDHD2_HUMAN             Reviewed;         711 AA.
AC   O94830; B3KWV2; Q9H8X7;
DE   RecName: Full=Phospholipase DDHD2;
DE            EC=3.1.1.-;
DE   AltName: Full=DDHD domain-containing protein 2;
DE   AltName: Full=KIAA0725p;
DE   AltName: Full=SAM, WWE and DDHD domain-containing protein 1;
GN   Name=DDHD2; Synonyms=KIAA0725, SAMWD1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   DDI1_HUMAN              Reviewed;         396 AA.
AC   Q8WTU0; Q7Z4U6; Q8WTS3;
DE   RecName: Full=Protein DDI1 homolog 1;
GN   Name=DDI1;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
//
ID   DDI2_HUMAN              Reviewed;         399 AA.
AC   Q5TDH0; A8KAE1; Q7RTZ0; Q9BRT1;
DE   RecName: Full=Protein DDI1 homolog 2;
GN   Name=DDI2;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
//
ID   DDIT3_HUMAN             Reviewed;         169 AA.
AC   P35638; F8VS99;
DE   RecName: Full=DNA damage-inducible transcript 3 protein;
DE            Short=DDIT-3;
DE   AltName: Full=C/EBP zeta;
DE   AltName: Full=C/EBP-homologous protein;
DE            Short=CHOP;
DE   AltName: Full=C/EBP-homologous protein 10;
DE            Short=CHOP-10;
DE   AltName: Full=CCAAT/enhancer-binding protein homologous protein;
DE   AltName: Full=Growth arrest and DNA damage-inducible protein GADD153;
GN   Name=DDIT3; Synonyms=CHOP, CHOP10, GADD153;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0001955; P:blood vessel maturation; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IDA:MGI.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006983; P:ER overload response; IEA:Ensembl.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:2000016; P:negative regulation of determination of dorsal identity; IDA:BHF-UCL.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IMP:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0043620; P:regulation of DNA-templated transcription in response to stress; TAS:BHF-UCL.
DR   GO; GO:0044324; P:regulation of transcription involved in anterior/posterior axis specification; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DDIT4_HUMAN             Reviewed;         232 AA.
AC   Q9NX09; Q9H0S3;
DE   RecName: Full=DNA damage-inducible transcript 4 protein;
DE   AltName: Full=HIF-1 responsive protein RTP801;
DE   AltName: Full=Protein regulated in development and DNA damage response 1;
DE            Short=REDD-1;
GN   Name=DDIT4; Synonyms=REDD1, RTP801;
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; ISS:UniProtKB.
DR   GO; GO:0045820; P:negative regulation of glycolytic process; IEA:Ensembl.
DR   GO; GO:1902532; P:negative regulation of intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:1901216; P:positive regulation of neuron death; ISS:UniProtKB.
DR   GO; GO:0043241; P:protein complex disassembly; IEA:Ensembl.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
//
ID   DDR1_HUMAN              Reviewed;         913 AA.
AC   Q08345; B5A975; B5A976; B7Z2K0; Q14196; Q16562; Q2L6H3; Q4LE50;
AC   Q5ST11; Q5ST12; Q6NSK4; Q9UD35; Q9UD36; Q9UD37; Q9UD86; Q9UDL2;
DE   RecName: Full=Epithelial discoidin domain-containing receptor 1;
DE            Short=Epithelial discoidin domain receptor 1;
DE            EC=2.7.10.1;
DE   AltName: Full=CD167 antigen-like family member A;
DE   AltName: Full=Cell adhesion kinase;
DE   AltName: Full=Discoidin receptor tyrosine kinase;
DE   AltName: Full=HGK2;
DE   AltName: Full=Mammary carcinoma kinase 10;
DE            Short=MCK-10;
DE   AltName: Full=Protein-tyrosine kinase 3A;
DE   AltName: Full=Protein-tyrosine kinase RTK-6;
DE   AltName: Full=TRK E;
DE   AltName: Full=Tyrosine kinase DDR;
DE   AltName: Full=Tyrosine-protein kinase CAK;
DE   AltName: CD_antigen=CD167a;
DE   Flags: Precursor;
GN   Name=DDR1; Synonyms=CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE;
DR   GuidetoPHARMACOLOGY; 1843; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0038062; F:protein tyrosine kinase collagen receptor activity; IDA:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0038063; P:collagen-activated tyrosine kinase receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043583; P:ear development; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:UniProtKB-KW.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0038083; P:peptidyl-tyrosine autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0010715; P:regulation of extracellular matrix disassembly; IMP:UniProtKB.
DR   GO; GO:0014909; P:smooth muscle cell migration; IMP:UniProtKB.
DR   GO; GO:0061302; P:smooth muscle cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0044319; P:wound healing, spreading of cells; IMP:UniProtKB.
//
ID   DDR2_HUMAN              Reviewed;         855 AA.
AC   Q16832; Q7Z730;
DE   RecName: Full=Discoidin domain-containing receptor 2;
DE            Short=Discoidin domain receptor 2;
DE            EC=2.7.10.1;
DE   AltName: Full=CD167 antigen-like family member B;
DE   AltName: Full=Discoidin domain-containing receptor tyrosine kinase 2;
DE   AltName: Full=Neurotrophic tyrosine kinase, receptor-related 3;
DE   AltName: Full=Receptor protein-tyrosine kinase TKT;
DE   AltName: Full=Tyrosine-protein kinase TYRO10;
DE   AltName: CD_antigen=CD167b;
DE   Flags: Precursor;
GN   Name=DDR2; Synonyms=NTRKR3, TKT, TYRO10;
DR   GuidetoPHARMACOLOGY; 1844; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0038062; F:protein tyrosine kinase collagen receptor activity; IDA:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031214; P:biomineral tissue development; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0035988; P:chondrocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0030199; P:collagen fibril organization; ISS:UniProtKB.
DR   GO; GO:0038063; P:collagen-activated tyrosine kinase receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0003416; P:endochondral bone growth; ISS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0090091; P:positive regulation of extracellular matrix disassembly; ISS:UniProtKB.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0030500; P:regulation of bone mineralization; IMP:UniProtKB.
DR   GO; GO:0010715; P:regulation of extracellular matrix disassembly; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   DDRGK_HUMAN             Reviewed;         314 AA.
AC   Q96HY6; A6NIU5; C9JSZ5; Q9BW47;
DE   RecName: Full=DDRGK domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=DDRGK1; Synonyms=C20orf116;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   DDT4L_HUMAN             Reviewed;         193 AA.
AC   Q96D03; B2R7C3;
DE   RecName: Full=DNA damage-inducible transcript 4-like protein;
DE   AltName: Full=HIF-1 responsive protein RTP801-like;
DE   AltName: Full=Protein regulated in development and DNA damage response 2;
DE            Short=REDD-2;
GN   Name=DDIT4L; Synonyms=REDD2, RTP801L;
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:InterPro.
//
ID   DDTL_HUMAN              Reviewed;         134 AA.
AC   A6NHG4; B4DJJ7;
DE   RecName: Full=D-dopachrome decarboxylase-like protein;
DE            EC=4.1.1.-;
DE   AltName: Full=D-dopachrome tautomerase-like protein;
GN   Name=DDTL;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
//
ID   DDX10_HUMAN             Reviewed;         875 AA.
AC   Q13206; B2RCQ3; Q5BJD8;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX10;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 10;
GN   Name=DDX10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
//
ID   DDX11_HUMAN             Reviewed;         970 AA.
AC   Q96FC9; Q13333; Q86VQ4; Q86W62; Q92498; Q92770; Q92998; Q92999;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX11;
DE            EC=3.6.4.13;
DE   AltName: Full=CHL1-related protein 1;
DE            Short=hCHLR1;
DE   AltName: Full=DEAD/H box protein 11;
DE   AltName: Full=Keratinocyte growth factor-regulated gene 2 protein;
DE            Short=KRG-2;
GN   Name=DDX11; Synonyms=CHL1, CHLR1, KRG2;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0000084; P:mitotic S phase; TAS:ProtInc.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007062; P:sister chromatid cohesion; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DDX12_HUMAN             Reviewed;         950 AA.
AC   Q92771;
DE   RecName: Full=Putative ATP-dependent RNA helicase DDX12;
DE            EC=3.6.4.13;
DE   AltName: Full=CHL1-related protein 2;
DE            Short=hCHLR2;
DE   AltName: Full=DEAD/H box protein 12;
GN   Name=DDX12P; Synonyms=CHLR2, DDX12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   DDX17_HUMAN             Reviewed;         729 AA.
AC   Q92841; B1AHM0; Q69YT1; Q6ICD6;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX17;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 17;
DE   AltName: Full=DEAD box protein p72;
DE   AltName: Full=RNA-dependent helicase p72;
GN   Name=DDX17;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0008186; F:RNA-dependent ATPase activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2001014; P:regulation of skeletal muscle cell differentiation; IMP:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DDX18_HUMAN             Reviewed;         670 AA.
AC   Q9NVP1; Q6GTZ9; Q6IAU4; Q92732; Q9BQB7;
DE   RecName: Full=ATP-dependent RNA helicase DDX18;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 18;
DE   AltName: Full=Myc-regulated DEAD box protein;
DE            Short=MrDb;
GN   Name=DDX18;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
//
ID   DDX1_HUMAN              Reviewed;         740 AA.
AC   Q92499;
DE   RecName: Full=ATP-dependent RNA helicase DDX1;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 1;
DE   AltName: Full=DEAD box protein retinoblastoma;
DE            Short=DBP-RB;
GN   Name=DDX1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0033677; F:DNA/RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IDA:UniProtKB.
DR   GO; GO:0008143; F:poly(A) binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEP:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006446; P:regulation of translational initiation; NAS:UniProtKB.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEA:Ensembl.
DR   GO; GO:0000245; P:spliceosomal complex assembly; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DDX20_HUMAN             Reviewed;         824 AA.
AC   Q9UHI6; Q96F72; Q9NVM3; Q9UF59; Q9UIY0; Q9Y659;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX20;
DE            EC=3.6.4.13;
DE   AltName: Full=Component of gems 3;
DE   AltName: Full=DEAD box protein 20;
DE   AltName: Full=DEAD box protein DP 103;
DE   AltName: Full=Gemin-3;
GN   Name=DDX20; Synonyms=DP103, GEMIN3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; TAS:ProtInc.
//
ID   DDX21_HUMAN             Reviewed;         783 AA.
AC   Q9NR30; B2RDL0; Q13436; Q5VX41; Q68D35;
DE   RecName: Full=Nucleolar RNA helicase 2;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 21;
DE   AltName: Full=Gu-alpha;
DE   AltName: Full=Nucleolar RNA helicase Gu;
DE   AltName: Full=Nucleolar RNA helicase II;
DE   AltName: Full=RH II/Gu;
GN   Name=DDX21;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEA:Ensembl.
//
ID   DDX23_HUMAN             Reviewed;         820 AA.
AC   Q9BUQ8; B2R600; O43188;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX23;
DE            EC=3.6.4.13;
DE   AltName: Full=100 kDa U5 snRNP-specific protein;
DE   AltName: Full=DEAD box protein 23;
DE   AltName: Full=PRP28 homolog;
DE   AltName: Full=U5-100kD;
GN   Name=DDX23;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0000354; P:cis assembly of pre-catalytic spliceosome; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   DDX24_HUMAN             Reviewed;         859 AA.
AC   Q9GZR7; E7EMJ4; Q4V9L5;
DE   RecName: Full=ATP-dependent RNA helicase DDX24;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 24;
GN   Name=DDX24;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; NAS:UniProtKB.
//
ID   DDX25_HUMAN             Reviewed;         483 AA.
AC   Q9UHL0; B2R6Z0; Q5XVN2; Q86W81; Q8IYP1;
DE   RecName: Full=ATP-dependent RNA helicase DDX25;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 25;
DE   AltName: Full=Gonadotropin-regulated testicular RNA helicase;
GN   Name=DDX25; Synonyms=GRTH;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0006406; P:mRNA export from nucleus; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
//
ID   DDX28_HUMAN             Reviewed;         540 AA.
AC   Q9NUL7;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX28;
DE            EC=3.6.4.13;
DE   AltName: Full=Mitochondrial DEAD box protein 28;
GN   Name=DDX28; Synonyms=MDDX28;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX27_HUMAN             Reviewed;         796 AA.
AC   Q96GQ7; A0AVB6; B7ZLY1; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96L97;
AC   Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX27;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 27;
GN   Name=DDX27; Synonyms=RHLP; ORFNames=HSPC259, PP3241;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX31_HUMAN             Reviewed;         851 AA.
AC   Q9H8H2; Q5K6N2; Q5K6N3; Q5K6N4; Q5VZJ4; Q5VZJ9; Q96E91; Q96NY2;
AC   Q96SX5; Q9H5K6;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX31;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 31;
DE   AltName: Full=Helicain;
GN   Name=DDX31;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX3X_HUMAN             Reviewed;         662 AA.
AC   O00571; A8K538; B4E3E8; O15536;
DE   RecName: Full=ATP-dependent RNA helicase DDX3X;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 3, X-chromosomal;
DE   AltName: Full=DEAD box, X isoform;
DE   AltName: Full=Helicase-like protein 2;
DE            Short=HLP2;
GN   Name=DDX3X; Synonyms=DBX, DDX3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IDA:UniProtKB.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0008143; F:poly(A) binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0035613; F:RNA stem-loop binding; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0031369; F:translation initiation factor binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0042256; P:mature ribosome assembly; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0071651; P:positive regulation of chemokine (C-C motif) ligand 5 production; TAS:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; TAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0010501; P:RNA secondary structure unwinding; IDA:UniProtKB.
DR   GO; GO:0034063; P:stress granule assembly; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DDX3Y_HUMAN             Reviewed;         660 AA.
AC   O15523; Q8IYV7;
DE   RecName: Full=ATP-dependent RNA helicase DDX3Y;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 3, Y-chromosomal;
GN   Name=DDX3Y; Synonyms=DBY;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   DDX41_HUMAN             Reviewed;         622 AA.
AC   Q9UJV9; B2RDC8; Q96BK6; Q96K05; Q9NT96; Q9NW04;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX41;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 41;
DE   AltName: Full=DEAD box protein abstrakt homolog;
GN   Name=DDX41; Synonyms=ABS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   DDX42_HUMAN             Reviewed;         938 AA.
AC   Q86XP3; A6NML1; A8KA43; O75619; Q68G51; Q96BK1; Q96HR7; Q9Y3V8;
DE   RecName: Full=ATP-dependent RNA helicase DDX42;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 42;
DE   AltName: Full=RNA helicase-like protein;
DE            Short=RHELP;
DE   AltName: Full=RNA helicase-related protein;
DE            Short=RNAHP;
DE   AltName: Full=SF3b DEAD box protein;
DE   AltName: Full=Splicing factor 3B-associated 125 kDa protein;
DE            Short=SF3b125;
GN   Name=DDX42;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
//
ID   DDX43_HUMAN             Reviewed;         648 AA.
AC   Q9NXZ2; Q6NXR1;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX43;
DE            EC=3.6.4.13;
DE   AltName: Full=Cancer/testis antigen 13;
DE            Short=CT13;
DE   AltName: Full=DEAD box protein 43;
DE   AltName: Full=DEAD box protein HAGE;
DE   AltName: Full=Helical antigen;
GN   Name=DDX43; Synonyms=HAGE;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
//
ID   DDX46_HUMAN             Reviewed;        1031 AA.
AC   Q7L014; O94894; Q96EI0; Q9Y658;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX46;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 46;
DE   AltName: Full=PRP5 homolog;
GN   Name=DDX46; Synonyms=KIAA0801;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   DDX47_HUMAN             Reviewed;         455 AA.
AC   Q9H0S4; B3KXP4; G5E955; Q96GM0; Q96NV8; Q9UI98;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX47;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 47;
GN   Name=DDX47;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
//
ID   DDX49_HUMAN             Reviewed;         483 AA.
AC   Q9Y6V7; Q53FJ1;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX49;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 49;
GN   Name=DDX49;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX4_HUMAN              Reviewed;         724 AA.
AC   Q9NQI0; A8K8Q2; B3KSF4; D6RDK4; E9PCD8; Q5M7Z3; Q86VX0; Q9NT92;
AC   Q9NYB1;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX4;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 4;
DE   AltName: Full=Vasa homolog;
GN   Name=DDX4; Synonyms=VASA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   DDX50_HUMAN             Reviewed;         737 AA.
AC   Q9BQ39; Q5VX37; Q8WV76; Q9BWI8;
DE   RecName: Full=ATP-dependent RNA helicase DDX50;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 50;
DE   AltName: Full=Gu-beta;
DE   AltName: Full=Nucleolar protein Gu2;
GN   Name=DDX50;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX51_HUMAN             Reviewed;         666 AA.
AC   Q8N8A6; A8MPT9; Q5CZ71; Q8IXK5; Q96ED1;
DE   RecName: Full=ATP-dependent RNA helicase DDX51;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 51;
GN   Name=DDX51;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   DDX52_HUMAN             Reviewed;         599 AA.
AC   Q9Y2R4; Q86YG1; Q8N213; Q9NVE0; Q9Y482;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX52;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase ROK1-like;
DE   AltName: Full=DEAD box protein 52;
GN   Name=DDX52; Synonyms=ROK1; ORFNames=HUSSY-19;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX53_HUMAN             Reviewed;         631 AA.
AC   Q86TM3; Q0D2N2; Q6NVV4;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX53;
DE            EC=3.6.4.13;
DE   AltName: Full=Cancer-associated gene protein;
DE   AltName: Full=Cancer/testis antigen 26;
DE            Short=CT26;
DE   AltName: Full=DEAD box protein 53;
DE   AltName: Full=DEAD box protein CAGE;
GN   Name=DDX53; Synonyms=CAGE;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   DDX54_HUMAN             Reviewed;         881 AA.
AC   Q8TDD1; Q86YT8; Q9BRZ1;
DE   RecName: Full=ATP-dependent RNA helicase DDX54;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase DP97;
DE   AltName: Full=DEAD box RNA helicase 97 kDa;
DE   AltName: Full=DEAD box protein 54;
GN   Name=DDX54;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DDX55_HUMAN             Reviewed;         600 AA.
AC   Q8NHQ9; Q658L6; Q9HCH7;
DE   RecName: Full=ATP-dependent RNA helicase DDX55;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 55;
GN   Name=DDX55; Synonyms=KIAA1595;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DDX58_HUMAN             Reviewed;         925 AA.
AC   O95786; A2RU81; Q5HYE1; Q5VYT1; Q9NT04;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX58;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 58;
DE   AltName: Full=RIG-I-like receptor 1;
DE            Short=RLR-1;
DE   AltName: Full=Retinoic acid-inducible gene 1 protein;
DE            Short=RIG-1;
DE   AltName: Full=Retinoic acid-inducible gene I protein;
DE            Short=RIG-I;
GN   Name=DDX58;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0039528; P:cytoplasmic pattern recognition receptor signaling pathway in response to virus; TAS:UniProtKB.
DR   GO; GO:0009597; P:detection of virus; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IDA:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0039529; P:RIG-I signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DDX56_HUMAN             Reviewed;         547 AA.
AC   Q9NY93; A4D2K9; C9JV95; Q6IAE2; Q9H9I8;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX56;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent 61 kDa nucleolar RNA helicase;
DE   AltName: Full=DEAD box protein 21;
DE   AltName: Full=DEAD box protein 56;
GN   Name=DDX56; Synonyms=DDX21, NOH61;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   DDX59_HUMAN             Reviewed;         619 AA.
AC   Q5T1V6; Q6PJL2; Q8IVW3; Q9H0W3;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX59;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 59;
DE   AltName: Full=Zinc finger HIT domain-containing protein 5;
GN   Name=DDX59; Synonyms=ZNHIT5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   DDX5_HUMAN              Reviewed;         614 AA.
AC   P17844; B5BU21; D3DU32; O75681; Q53Y61;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX5;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 5;
DE   AltName: Full=RNA helicase p68;
GN   Name=DDX5; Synonyms=G17P1, HELR, HLR1;
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IEA:Ensembl.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; IMP:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045069; P:regulation of viral genome replication; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DDX6L_HUMAN             Reviewed;        1706 AA.
AC   Q5H9U9; Q96ND6;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX60-like;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 60-like;
GN   Name=DDX60L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   DDX60_HUMAN             Reviewed;        1712 AA.
AC   Q8IY21; Q6PK35; Q9NVE3;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX60;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 60;
GN   Name=DDX60;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.
DR   GO; GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
//
ID   DDX6_HUMAN              Reviewed;         483 AA.
AC   P26196; Q5D048;
DE   RecName: Full=Probable ATP-dependent RNA helicase DDX6;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase p54;
DE   AltName: Full=DEAD box protein 6;
DE   AltName: Full=Oncogene RCK;
GN   Name=DDX6; Synonyms=HLR2, RCK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IDA:MGI.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   DEAF1_HUMAN             Reviewed;         565 AA.
AC   O75398; A8K1F8; A8K5R8; C7T5V5; O15152; O75399; O75510; O75511;
AC   O75512; O75513; Q9UET1;
DE   RecName: Full=Deformed epidermal autoregulatory factor 1 homolog;
DE   AltName: Full=Nuclear DEAF-1-related transcriptional regulator;
DE            Short=NUDR;
DE   AltName: Full=Suppressin;
DE   AltName: Full=Zinc finger MYND domain-containing protein 5;
GN   Name=DEAF1; Synonyms=SPN, ZMYND5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0048706; P:embryonic skeletal system development; ISS:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; TAS:ProtInc.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   DEC1_HUMAN              Reviewed;          70 AA.
AC   Q9P2X7;
DE   RecName: Full=Deleted in esophageal cancer 1;
DE   AltName: Full=Candidate tumor suppressor CTS9;
GN   Name=DEC1; Synonyms=CTS9;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   DECR2_HUMAN             Reviewed;         292 AA.
AC   Q9NUI1; Q6ZRS7; Q96ET0;
DE   RecName: Full=Peroxisomal 2,4-dienoyl-CoA reductase;
DE            Short=pDCR;
DE            EC=1.3.1.34;
DE   AltName: Full=2,4-dienoyl-CoA reductase 2;
GN   Name=DECR2; Synonyms=PDCR;
DR   GO; GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   DECR_HUMAN              Reviewed;         335 AA.
AC   Q16698; Q2M304; Q93085;
DE   RecName: Full=2,4-dienoyl-CoA reductase, mitochondrial;
DE            EC=1.3.1.34;
DE   AltName: Full=2,4-dienoyl-CoA reductase [NADPH];
DE            Short=4-enoyl-CoA reductase [NADPH];
DE   Flags: Precursor;
GN   Name=DECR1; Synonyms=DECR;
DR   GO; GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DEDD2_HUMAN             Reviewed;         326 AA.
AC   Q8WXF8; Q8NBR2; Q8NES1; Q8TAA8; Q96D35;
DE   RecName: Full=DNA-binding death effector domain-containing protein 2;
DE   AltName: Full=DED-containing protein FLAME-3;
DE   AltName: Full=FADD-like anti-apoptotic molecule 3;
GN   Name=DEDD2; Synonyms=FLAME3; ORFNames=PSEC0004;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; NAS:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; NAS:UniProtKB.
DR   GO; GO:0016075; P:rRNA catabolic process; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DEDD_HUMAN              Reviewed;         318 AA.
AC   O75618; D3DVF5; O60737;
DE   RecName: Full=Death effector domain-containing protein;
DE   AltName: Full=DEDPro1;
DE   AltName: Full=Death effector domain-containing testicular molecule;
DE   AltName: Full=FLDED-1;
GN   Name=DEDD; Synonyms=DEDPRO1, DEFT; ORFNames=KE05;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:ProtInc.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:1901837; P:negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DEF1_HUMAN              Reviewed;          94 AA.
AC   P59665; P11479; Q14125; Q6EZF6;
DE   RecName: Full=Neutrophil defensin 1;
DE   AltName: Full=Defensin, alpha 1;
DE   AltName: Full=HNP-1;
DE            Short=HP-1;
DE            Short=HP1;
DE   Contains:
DE     RecName: Full=HP 1-56;
DE   Contains:
DE     RecName: Full=Neutrophil defensin 2;
DE     AltName: Full=HNP-2;
DE              Short=HP-2;
DE              Short=HP2;
DE   Flags: Precursor;
GN   Name=DEFA1; Synonyms=DEF1, DEFA2, MRS;
GN   and
GN   Name=DEFA1B;
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   DEF3_HUMAN              Reviewed;          94 AA.
AC   P59666; P11479; Q14125;
DE   RecName: Full=Neutrophil defensin 3;
DE   AltName: Full=Defensin, alpha 3;
DE   AltName: Full=HNP-3;
DE            Short=HP-3;
DE            Short=HP3;
DE   Contains:
DE     RecName: Full=HP 3-56;
DE   Contains:
DE     RecName: Full=Neutrophil defensin 2;
DE     AltName: Full=HNP-2;
DE              Short=HP-2;
DE              Short=HP2;
DE   Flags: Precursor;
GN   Name=DEFA3; Synonyms=DEF3;
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   DEF4_HUMAN              Reviewed;          97 AA.
AC   P12838; Q6EZF8;
DE   RecName: Full=Neutrophil defensin 4;
DE   AltName: Full=Defensin, alpha 4;
DE   AltName: Full=HNP-4;
DE            Short=HP-4;
DE   Flags: Precursor;
GN   Name=DEFA4; Synonyms=DEF4;
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   DEF5_HUMAN              Reviewed;          94 AA.
AC   Q01523; A0JDY6; Q3KNV2;
DE   RecName: Full=Defensin-5;
DE   AltName: Full=Defensin, alpha 5;
DE   AltName: Full=HD5(20-94);
DE   Contains:
DE     RecName: Full=HD5(23-94);
DE   Contains:
DE     RecName: Full=HD5(29-94);
DE   Contains:
DE     RecName: Full=HD5(56-94);
DE   Contains:
DE     RecName: Full=HD5(63-94);
DE   Flags: Precursor;
GN   Name=DEFA5; Synonyms=DEF5;
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   DEF6_HUMAN              Reviewed;         100 AA.
AC   Q01524; Q6EZF9;
DE   RecName: Full=Defensin-6;
DE   AltName: Full=Defensin, alpha 6;
DE   Flags: Precursor;
GN   Name=DEFA6; Synonyms=DEF6;
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   DEFB1_HUMAN             Reviewed;          68 AA.
AC   P60022; Q09753;
DE   RecName: Full=Beta-defensin 1;
DE            Short=BD-1;
DE            Short=hBD-1;
DE   AltName: Full=Defensin, beta 1;
DE   Flags: Precursor;
GN   Name=DEFB1; Synonyms=BD1, HBD1;
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; ISS:UniProtKB.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0009617; P:response to bacterium; IDA:UniProtKB.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
//
ID   DEFI6_HUMAN             Reviewed;         631 AA.
AC   Q9H4E7; Q86VF4;
DE   RecName: Full=Differentially expressed in FDCP 6 homolog;
DE            Short=DEF-6;
DE   AltName: Full=IRF4-binding protein;
GN   Name=DEF6; Synonyms=IBP;
//
ID   DEFI8_HUMAN             Reviewed;         512 AA.
AC   Q6ZN54; B3KT65; B4DK62; B4E0S9; B7Z3H6; H3BUG7; Q8N8N3; Q9NXL0;
DE   RecName: Full=Differentially expressed in FDCP 8 homolog;
DE            Short=DEF-8;
GN   Name=DEF8;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DEFM_HUMAN              Reviewed;         243 AA.
AC   Q9HBH1; Q8WUN6;
DE   RecName: Full=Peptide deformylase, mitochondrial;
DE            EC=3.5.1.88;
DE   AltName: Full=Polypeptide deformylase;
DE   Flags: Precursor;
GN   Name=PDF; Synonyms=PDF1A;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0042586; F:peptide deformylase activity; IDA:HGNC.
DR   GO; GO:0031365; P:N-terminal protein amino acid modification; IDA:HGNC.
DR   GO; GO:0018206; P:peptidyl-methionine modification; IDA:HGNC.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
//
ID   DEGS1_HUMAN             Reviewed;         323 AA.
AC   O15121;
DE   RecName: Full=Sphingolipid delta(4)-desaturase DES1;
DE            EC=1.14.-.-;
DE   AltName: Full=Cell migration-inducing gene 15 protein;
DE   AltName: Full=Degenerative spermatocyte homolog 1;
DE   AltName: Full=Membrane lipid desaturase;
GN   Name=DEGS1; Synonyms=DES1, MLD; ORFNames=MIG15;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; TAS:ProtInc.
//
ID   DEGS2_HUMAN             Reviewed;         323 AA.
AC   Q6QHC5; Q6P492;
DE   RecName: Full=Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2;
DE            EC=1.-.-.-;
DE            EC=1.14.-.-;
DE   AltName: Full=Degenerative spermatocyte homolog 2;
GN   Name=DEGS2; Synonyms=C14orf66;
DR   GO; GO:0042284; F:sphingolipid delta-4 desaturase activity; IEA:Ensembl.
DR   GO; GO:0000170; F:sphingosine hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006667; P:sphinganine metabolic process; IEA:Ensembl.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   DEK_HUMAN               Reviewed;         375 AA.
AC   P35659; B2R6K6; B4DN37; Q5TGV4; Q5TGV5;
DE   RecName: Full=Protein DEK;
GN   Name=DEK;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:2000779; P:regulation of double-strand break repair; IMP:MGI.
DR   GO; GO:2001032; P:regulation of double-strand break repair via nonhomologous end joining; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
//
ID   DELE_HUMAN              Reviewed;         515 AA.
AC   Q14154; Q969R4; Q96EU9;
DE   RecName: Full=Death ligand signal enhancer;
DE   Flags: Precursor;
GN   Name=KIAA0141; Synonyms=DELE;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProtKB.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
//
ID   DEMA_HUMAN              Reviewed;         405 AA.
AC   Q08495; A8K0T5; B3KP70; B3KRH3; E9PEJ0; Q13215; Q9BRE3;
DE   RecName: Full=Dematin;
DE   AltName: Full=Dematin actin-binding protein;
DE   AltName: Full=Erythrocyte membrane protein band 4.9;
GN   Name=DMTN; Synonyms=DMT, EPB49;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0090527; P:actin filament reorganization; ISS:UniProtKB.
DR   GO; GO:0035585; P:calcium-mediated signaling using extracellular calcium source; ISS:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; ISS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0048821; P:erythrocyte development; ISS:UniProtKB.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0090315; P:negative regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; ISS:UniProtKB.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.
DR   GO; GO:2001046; P:positive regulation of integrin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:1901731; P:positive regulation of platelet aggregation; ISS:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0070560; P:protein secretion by platelet; ISS:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; IMP:UniProtKB.
DR   GO; GO:0010591; P:regulation of lamellipodium assembly; IMP:UniProtKB.
//
ID   DEN1A_HUMAN             Reviewed;        1009 AA.
AC   Q8TEH3; A8MZA3; B1AM80; B7Z3C8; B7Z669; D3PFD3; Q05C88; Q5VWF0;
AC   Q6PJZ5; Q8IVD6; Q9H796;
DE   RecName: Full=DENN domain-containing protein 1A;
DE   AltName: Full=Connecdenn 1;
DE            Short=Connecdenn;
DE   AltName: Full=Protein FAM31A;
GN   Name=DENND1A; Synonyms=FAM31A, KIAA1608;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0032483; P:regulation of Rab protein signal transduction; IDA:FlyBase.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:Ensembl.
//
ID   DEN1B_HUMAN             Reviewed;         426 AA.
AC   Q6P3S1; B5MD89; D3PFD5; Q5T3B8; Q5T3B9; Q5T3C1; Q5TAI8; Q6B0I8;
AC   Q8NDT1; Q8TBE6; Q9H774; Q9NXU2;
DE   RecName: Full=DENN domain-containing protein 1B;
DE   AltName: Full=Connecdenn 2;
DE   AltName: Full=Protein FAM31B;
GN   Name=DENND1B; Synonyms=C1orf218, FAM31B;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN1C_HUMAN             Reviewed;         801 AA.
AC   Q8IV53; B4E051; D3PFD4; Q8NDB1; Q9H5Z2;
DE   RecName: Full=DENN domain-containing protein 1C;
DE   AltName: Full=Connecdenn 3;
DE   AltName: Full=Protein FAM31C;
GN   Name=DENND1C; Synonyms=FAM31C;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN2A_HUMAN             Reviewed;        1009 AA.
AC   Q9ULE3; C9JUI3; Q1RMD5; Q86XY0;
DE   RecName: Full=DENN domain-containing protein 2A;
GN   Name=DENND2A; Synonyms=KIAA1277;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   DEN2C_HUMAN             Reviewed;         928 AA.
AC   Q68D51; B1AL26; Q5TCX6; Q6P3R3;
DE   RecName: Full=DENN domain-containing protein 2C;
GN   Name=DENND2C;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN2D_HUMAN             Reviewed;         471 AA.
AC   Q9H6A0; Q5T5V6; Q9BSU0;
DE   RecName: Full=DENN domain-containing protein 2D;
GN   Name=DENND2D;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN4B_HUMAN             Reviewed;        1496 AA.
AC   O75064; Q5T4K0;
DE   RecName: Full=DENN domain-containing protein 4B;
GN   Name=DENND4B; Synonyms=KIAA0476;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0032483; P:regulation of Rab protein signal transduction; IDA:FlyBase.
//
ID   DEN4C_HUMAN             Reviewed;        1673 AA.
AC   Q5VZ89; A2A3R1; A2A3R2; A2A3R3; A2A3R9; Q6AI48; Q6ZUB3; Q8NCY7;
AC   Q9H6N4; Q9NUT1; Q9NWA5; Q9NWT3;
DE   RecName: Full=DENN domain-containing protein 4C;
GN   Name=DENND4C; Synonyms=C9orf55, C9orf55B;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN5A_HUMAN             Reviewed;        1287 AA.
AC   Q6IQ26; B4DJ15; E9PS91; Q96GN3; Q9H6U7; Q9UFV0; Q9UPR1;
DE   RecName: Full=DENN domain-containing protein 5A;
DE   AltName: Full=Rab6-interacting protein 1;
DE            Short=Rab6IP1;
GN   Name=DENND5A; Synonyms=KIAA1091, RAB6IP1;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN5B_HUMAN             Reviewed;        1274 AA.
AC   Q6ZUT9; B5ME75; Q59FW8; Q68CZ7; Q6NUJ0; Q7Z3F9; Q8N973; Q8WUC8;
DE   RecName: Full=DENN domain-containing protein 5B;
DE   AltName: Full=Rab6IP1-like protein;
GN   Name=DENND5B;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN6A_HUMAN             Reviewed;         608 AA.
AC   Q8IWF6; Q7Z5T4; Q8N235; Q8TEG8;
DE   RecName: Full=Protein DENND6A;
DE   AltName: Full=DENN domain-containing protein 6A;
GN   Name=DENND6A; Synonyms=FAM116A;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEN6B_HUMAN             Reviewed;         585 AA.
AC   Q8NEG7; A6X8I5;
DE   RecName: Full=Protein DENND6B;
DE   AltName: Full=DENN domain-containing protein 6B;
GN   Name=DENND6B; Synonyms=FAM116B;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEND3_HUMAN             Reviewed;        1198 AA.
AC   A2RUS2; B7ZM28; O94947; Q2TAM7; Q6ZMS6; Q96DK3;
DE   RecName: Full=DENN domain-containing protein 3;
GN   Name=DENND3; Synonyms=KIAA0870;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0044257; P:cellular protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   DEND_HUMAN              Reviewed;         711 AA.
AC   O94850;
DE   RecName: Full=Dendrin;
GN   Name=DDN; Synonyms=KIAA0749;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   DENR_HUMAN              Reviewed;         198 AA.
AC   O43583; Q9H3U6; Q9UKZ0;
DE   RecName: Full=Density-regulated protein;
DE            Short=DRP;
DE   AltName: Full=Protein DRP1;
DE   AltName: Full=Smooth muscle cell-associated protein 3;
DE            Short=SMAP-3;
GN   Name=DENR; Synonyms=DRP1; ORFNames=H14;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
//
ID   DEOC_HUMAN              Reviewed;         318 AA.
AC   Q9Y315; Q53HN9; Q6PHW2;
DE   RecName: Full=Putative deoxyribose-phosphate aldolase;
DE            Short=DERA;
DE            EC=4.1.2.4;
DE   AltName: Full=2-deoxy-D-ribose 5-phosphate aldolase;
DE   AltName: Full=Phosphodeoxyriboaldolase;
DE            Short=Deoxyriboaldolase;
GN   Name=DERA; ORFNames=CGI-26;
DR   GO; GO:0004139; F:deoxyribose-phosphate aldolase activity; IDA:UniProtKB.
DR   GO; GO:0046121; P:deoxyribonucleoside catabolic process; IDA:UniProtKB.
DR   GO; GO:0009264; P:deoxyribonucleotide catabolic process; IEA:InterPro.
DR   GO; GO:0046386; P:deoxyribose phosphate catabolic process; IEA:UniProtKB-UniPathway.
//
ID   DEP1A_HUMAN             Reviewed;         811 AA.
AC   Q5TB30; A8QXE0; A8QXE1; Q05DU3; Q5TB28; Q9H9I3; Q9NX21; Q9NXZ0;
DE   RecName: Full=DEP domain-containing protein 1A;
GN   Name=DEPDC1; Synonyms=DEPDC1A;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DEP1B_HUMAN             Reviewed;         529 AA.
AC   Q8WUY9; A8K3R9; B4DUT4; Q86WJ3; Q8IZY6; Q9NUN3; Q9NW57;
DE   RecName: Full=DEP domain-containing protein 1B;
DE   AltName: Full=HBV X-transactivated gene 8 protein;
DE   AltName: Full=HBV XAg-transactivated protein 8;
GN   Name=DEPDC1B; Synonyms=XTP8;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   DEPD4_HUMAN             Reviewed;         294 AA.
AC   Q8N2C3; Q496C8; Q96BW0;
DE   RecName: Full=DEP domain-containing protein 4;
GN   Name=DEPDC4;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DEPD5_HUMAN             Reviewed;        1603 AA.
AC   O75140; A6H8V6; A8MPX9; B4DH93; B9EGN9; Q5K3V5; Q5THY9; Q5THZ0;
AC   Q5THZ1; Q5THZ3; Q68DR1; Q6MZX3; Q6PEZ1; Q9UGV8; Q9UH13;
DE   RecName: Full=DEP domain-containing protein 5;
GN   Name=DEPDC5; Synonyms=KIAA0645;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DEPD7_HUMAN             Reviewed;         511 AA.
AC   Q96QD5; G5E941; Q8N602; Q8NCU9; Q9UGK5;
DE   RecName: Full=DEP domain-containing protein 7;
DE   AltName: Full=Protein TR2/D15;
GN   Name=DEPDC7;
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   DEPP_HUMAN              Reviewed;         212 AA.
AC   Q9NTK1; B2R6A1; O94997; Q5T735; Q76MX8;
DE   RecName: Full=Protein DEPP;
DE   AltName: Full=Decidual protein induced by progesterone;
DE   AltName: Full=Fasting-induced gene protein;
DE            Short=FIG;
GN   Name=DEPP; Synonyms=C10orf10, FIG;
//
ID   DERL1_HUMAN             Reviewed;         251 AA.
AC   Q9BUN8; B3KW41; E9PH19;
DE   RecName: Full=Derlin-1;
DE   AltName: Full=Degradation in endoplasmic reticulum protein 1;
DE            Short=DERtrin-1;
DE   AltName: Full=Der1-like protein 1;
GN   Name=DERL1; Synonyms=DER1; ORFNames=UNQ243/PRO276;
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; TAS:UniProtKB.
DR   GO; GO:0019060; P:intracellular transport of viral protein in host cell; TAS:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IMP:MGI.
DR   GO; GO:0030970; P:retrograde protein transport, ER to cytosol; IDA:UniProtKB.
//
ID   DERL2_HUMAN             Reviewed;         239 AA.
AC   Q9GZP9; Q9Y3A7;
DE   RecName: Full=Derlin-2;
DE   AltName: Full=Degradation in endoplasmic reticulum protein 2;
DE            Short=DERtrin-2;
DE   AltName: Full=Der1-like protein 2;
DE   AltName: Full=F-LAN-1;
DE   AltName: Full=F-LANa;
GN   Name=DERL2; Synonyms=DER2, FLANA; ORFNames=CGI-101, SBBI53;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030970; P:retrograde protein transport, ER to cytosol; IMP:UniProtKB.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
//
ID   DERL3_HUMAN             Reviewed;         235 AA.
AC   Q96Q80; F2Z3B6; Q6ICJ6; Q6PEX0; Q6ZUB5;
DE   RecName: Full=Derlin-3;
DE   AltName: Full=Degradation in endoplasmic reticulum protein 3;
DE            Short=DERtrin-3;
DE   AltName: Full=Der1-like protein 3;
GN   Name=DERL3; Synonyms=C22orf14, DER3, LLN2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
//
ID   DERM_HUMAN              Reviewed;         201 AA.
AC   Q07507; A8K981; Q8N4R2; Q9UIX8;
DE   RecName: Full=Dermatopontin;
DE   AltName: Full=Tyrosine-rich acidic matrix protein;
DE            Short=TRAMP;
DE   Flags: Precursor;
GN   Name=DPT;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
//
ID   DESI1_HUMAN             Reviewed;         168 AA.
AC   Q6ICB0;
DE   RecName: Full=Desumoylating isopeptidase 1;
DE            Short=DeSI-1;
DE            EC=3.4.-.-;
DE   AltName: Full=PPPDE peptidase domain-containing protein 2;
DE   AltName: Full=Protein FAM152B;
GN   Name=DESI1; Synonyms=FAM152B, PPPDE2;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
//
ID   DESI2_HUMAN             Reviewed;         194 AA.
AC   Q9BSY9; B1APK6; Q5VVC6; Q9NYS2; Q9Y3E4;
DE   RecName: Full=Desumoylating isopeptidase 2;
DE            Short=DeSI-2;
DE            EC=3.4.-.-;
DE   AltName: Full=PPPDE peptidase domain-containing protein 1;
DE   AltName: Full=Protein FAM152A;
GN   Name=DESI2; Synonyms=C1orf121, FAM152A, PPPDE1;
GN   ORFNames=CGI-146, PNAS-4;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
//
ID   DESM_HUMAN              Reviewed;         470 AA.
AC   P17661; Q15787; Q549R7; Q549R8; Q549R9; Q8IZR1; Q8IZR6; Q8NES2;
AC   Q8NEU6; Q8TAC4; Q8TCX2; Q8TD99; Q9UHN5; Q9UJ80;
DE   RecName: Full=Desmin;
GN   Name=DES;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
//
ID   DESP_HUMAN              Reviewed;        2871 AA.
AC   P15924; B2RTT2; D7RX09; O75993; Q14189; Q9UHN4;
DE   RecName: Full=Desmoplakin;
DE            Short=DP;
DE   AltName: Full=250/210 kDa paraneoplastic pemphigus antigen;
GN   Name=DSP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0002934; P:desmosome organization; ISS:BHF-UCL.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0045109; P:intermediate filament organization; ISS:BHF-UCL.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
DR   GO; GO:0071896; P:protein localization to adherens junction; ISS:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0003223; P:ventricular compact myocardium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   DEST_HUMAN              Reviewed;         165 AA.
AC   P60981; B2R6N2; B4DYA6; P18282; Q5W166; Q6IAW2;
DE   RecName: Full=Destrin;
DE   AltName: Full=Actin-depolymerizing factor;
DE            Short=ADF;
GN   Name=DSTN; Synonyms=ACTDP, DSN;
DR   GO; GO:0030042; P:actin filament depolymerization; IEA:InterPro.
DR   GO; GO:0051014; P:actin filament severing; TAS:ProtInc.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; IEA:Ensembl.
//
ID   DET1_HUMAN              Reviewed;         550 AA.
AC   Q7L5Y6; B3KNN6; Q2VPC0; Q9NWD5;
DE   RecName: Full=DET1 homolog;
DE   AltName: Full=De-etiolated-1 homolog;
GN   Name=DET1;
//
ID   DEUP1_HUMAN             Reviewed;         604 AA.
AC   Q05D60; Q8NEF1; Q96LL7;
DE   RecName: Full=Deuterosome protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 67;
GN   Name=CCDC67; Synonyms=DEUP1;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0098535; P:de novo centriole assembly; ISS:UniProtKB.
//
ID   DEXI_HUMAN              Reviewed;          95 AA.
AC   O95424; B2RAA7;
DE   RecName: Full=Dexamethasone-induced protein;
DE   AltName: Full=Protein MYLE;
GN   Name=DEXI; Synonyms=MYLE;
//
ID   DFB4A_HUMAN             Reviewed;          64 AA.
AC   O15263; Q52LC0;
DE   RecName: Full=Beta-defensin 4A;
DE   AltName: Full=Beta-defensin 2;
DE            Short=BD-2;
DE            Short=hBD-2;
DE   AltName: Full=Defensin, beta 2;
DE   AltName: Full=Skin-antimicrobial peptide 1;
DE            Short=SAP1;
DE   Flags: Precursor;
GN   Name=DEFB4A; Synonyms=DEFB102, DEFB2, DEFB4;
GN   and
GN   Name=DEFB4B;
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   DFFA_HUMAN              Reviewed;         331 AA.
AC   O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6;
DE   RecName: Full=DNA fragmentation factor subunit alpha;
DE   AltName: Full=DNA fragmentation factor 45 kDa subunit;
DE            Short=DFF-45;
DE   AltName: Full=Inhibitor of CAD;
DE            Short=ICAD;
GN   Name=DFFA; Synonyms=DFF1, DFF45; ORFNames=H13;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:1902511; P:negative regulation of apoptotic DNA fragmentation; IDA:MGI.
DR   GO; GO:1900118; P:negative regulation of execution phase of apoptosis; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0070242; P:thymocyte apoptotic process; IEA:Ensembl.
//
ID   DFFB_HUMAN              Reviewed;         338 AA.
AC   O76075; O60521; Q5SR22; Q9BYI4; Q9BYI5; Q9BYI6;
DE   RecName: Full=DNA fragmentation factor subunit beta;
DE            EC=3.-.-.-;
DE   AltName: Full=Caspase-activated deoxyribonuclease;
DE            Short=CAD;
DE            Short=Caspase-activated DNase;
DE   AltName: Full=Caspase-activated nuclease;
DE            Short=CPAN;
DE   AltName: Full=DNA fragmentation factor 40 kDa subunit;
DE            Short=DFF-40;
GN   Name=DFFB; Synonyms=CAD, DFF2, DFF40;
DR   GO; GO:0004536; F:deoxyribonuclease activity; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0030263; P:apoptotic chromosome condensation; IDA:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IDA:MGI.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
//
ID   DFNA5_HUMAN             Reviewed;         496 AA.
AC   O60443; A4D156; B2RAX9; B3KT05; O14590; Q08AQ8; Q9UBV3;
DE   RecName: Full=Non-syndromic hearing impairment protein 5;
DE   AltName: Full=Inversely correlated with estrogen receptor expression 1;
DE            Short=ICERE-1;
GN   Name=DFNA5; Synonyms=ICERE1;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060113; P:inner ear receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   DG2L6_HUMAN             Reviewed;         337 AA.
AC   Q6ZPD8; Q6IEE2;
DE   RecName: Full=Diacylglycerol O-acyltransferase 2-like protein 6;
DE            EC=2.3.1.-;
DE   AltName: Full=Diacylglycerol O-acyltransferase candidate 3;
DE            Short=hDC3;
GN   Name=DGAT2L6; Synonyms=DC3;
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
//
ID   DG2L7_HUMAN             Reviewed;         249 AA.
AC   Q6IED9;
DE   RecName: Full=Putative diacylglycerol O-acyltransferase 2-like protein DGAT2L7P;
DE            EC=2.3.1.-;
DE   AltName: Full=Diacylglycerol O-acyltransferase 2-like 7 pseudogene;
DE   Flags: Precursor;
GN   Name=DGAT2L7P;
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
//
ID   DGAT1_HUMAN             Reviewed;         488 AA.
AC   O75907; B2RWQ2; D3DWL6; Q96BB8;
DE   RecName: Full=Diacylglycerol O-acyltransferase 1;
DE            EC=2.3.1.20;
DE   AltName: Full=ACAT-related gene product 1;
DE   AltName: Full=Acyl-CoA retinol O-fatty-acyltransferase;
DE            Short=ARAT;
DE            Short=Retinol O-fatty-acyltransferase;
DE            EC=2.3.1.76;
DE   AltName: Full=Diglyceride acyltransferase;
GN   Name=DGAT1; Synonyms=AGRP1, DGAT;
DR   GO; GO:0003846; F:2-acylglycerol O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050252; F:retinol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; TAS:ProtInc.
DR   GO; GO:0036155; P:acylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046339; P:diacylglycerol metabolic process; ISS:BHF-UCL.
DR   GO; GO:0055089; P:fatty acid homeostasis; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0019915; P:lipid storage; ISS:BHF-UCL.
DR   GO; GO:0035336; P:long-chain fatty-acyl-CoA metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006641; P:triglyceride metabolic process; TAS:ProtInc.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; IMP:BHF-UCL.
//
ID   DGAT2_HUMAN             Reviewed;         388 AA.
AC   Q96PD7; A6ND76; Q5U810; Q68CL3; Q68DJ0; Q8NDB7; Q96BS0; Q9BYE5;
DE   RecName: Full=Diacylglycerol O-acyltransferase 2;
DE            EC=2.3.1.20;
DE   AltName: Full=Acyl-CoA retinol O-fatty-acyltransferase;
DE            Short=ARAT;
DE            Short=Retinol O-fatty-acyltransferase;
DE            EC=2.3.1.76;
DE   AltName: Full=Diglyceride acyltransferase 2;
GN   Name=DGAT2; ORFNames=HMFN1045, UNQ738/PRO1433;
DR   GO; GO:0003846; F:2-acylglycerol O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0050252; F:retinol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0036155; P:acylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071400; P:cellular response to oleic acid; ISS:BHF-UCL.
DR   GO; GO:0035356; P:cellular triglyceride homeostasis; ISS:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0046339; P:diacylglycerol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0060613; P:fat pad development; ISS:BHF-UCL.
DR   GO; GO:0055089; P:fatty acid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0019915; P:lipid storage; ISS:BHF-UCL.
DR   GO; GO:0035336; P:long-chain fatty-acyl-CoA metabolic process; IDA:BHF-UCL.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; ISS:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0097006; P:regulation of plasma lipoprotein particle levels; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IDA:UniProtKB.
//
ID   DGC14_HUMAN             Reviewed;         476 AA.
AC   Q96DF8; Q49AH7; Q9BTZ4;
DE   RecName: Full=Protein DGCR14;
DE   AltName: Full=DiGeorge syndrome critical region 13;
DE   AltName: Full=DiGeorge syndrome critical region 14;
DE   AltName: Full=DiGeorge syndrome protein H;
DE            Short=DGS-H;
DE   AltName: Full=Protein ES2;
GN   Name=DGCR14; Synonyms=DGCR13, DGSH, DGSI, ES2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
//
ID   DGC6L_HUMAN             Reviewed;         220 AA.
AC   Q9BY27; A8K1N7; D3DX29; Q9BW33;
DE   RecName: Full=Protein DGCR6L;
DE   AltName: Full=DiGeorge syndrome critical region 6-like protein;
GN   Name=DGCR6L;
//
ID   DGCR6_HUMAN             Reviewed;         220 AA.
AC   Q14129; B2RCH5; D3DX15; Q9BY28;
DE   RecName: Full=Protein DGCR6;
DE   AltName: Full=DiGeorge syndrome critical region 6;
GN   Name=DGCR6;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
//
ID   DGCR8_HUMAN             Reviewed;         773 AA.
AC   Q8WYQ5; B2R8G1; Q6DCB2; Q6MZE9; Q6Y2L0; Q96G39; Q96GP8; Q9H6L8;
AC   Q9H6T7; Q9NRW2;
DE   RecName: Full=Microprocessor complex subunit DGCR8;
DE   AltName: Full=DiGeorge syndrome critical region 8;
GN   Name=DGCR8; Synonyms=C22orf12, DGCRK6; ORFNames=LP4941;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031053; P:primary miRNA processing; IDA:MGI.
//
ID   DGKA_HUMAN              Reviewed;         735 AA.
AC   P23743; O75481; O75482; O75483; O95217; Q3ZE25; Q8IZ56; Q8N5Q2;
DE   RecName: Full=Diacylglycerol kinase alpha;
DE            Short=DAG kinase alpha;
DE            EC=2.7.1.107;
DE   AltName: Full=80 kDa diacylglycerol kinase;
DE   AltName: Full=Diglyceride kinase alpha;
DE            Short=DGK-alpha;
GN   Name=DGKA; Synonyms=DAGK, DAGK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; TAS:ProtInc.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   DGKB_HUMAN              Reviewed;         804 AA.
AC   Q9Y6T7; A4D116; A4D117; A8MXU2; O75241; Q2M377; Q75MF9; Q75MU7;
AC   Q86UI5; Q86UM9; Q9UQ29;
DE   RecName: Full=Diacylglycerol kinase beta;
DE            Short=DAG kinase beta;
DE            EC=2.7.1.107;
DE   AltName: Full=90 kDa diacylglycerol kinase;
DE   AltName: Full=Diglyceride kinase beta;
DE            Short=DGK-beta;
GN   Name=DGKB; Synonyms=DAGK2, KIAA0718;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   DGKD_HUMAN              Reviewed;        1214 AA.
AC   Q16760; Q14158; Q6PK55; Q8NG53;
DE   RecName: Full=Diacylglycerol kinase delta;
DE            Short=DAG kinase delta;
DE            EC=2.7.1.107;
DE   AltName: Full=130 kDa diacylglycerol kinase;
DE   AltName: Full=Diglyceride kinase delta;
DE            Short=DGK-delta;
GN   Name=DGKD; Synonyms=KIAA0145;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0046339; P:diacylglycerol metabolic process; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010033; P:response to organic substance; IDA:UniProtKB.
DR   GO; GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   DGKE_HUMAN              Reviewed;         567 AA.
AC   P52429; Q9UKQ3;
DE   RecName: Full=Diacylglycerol kinase epsilon;
DE            Short=DAG kinase epsilon;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase epsilon;
DE            Short=DGK-epsilon;
GN   Name=DGKE; Synonyms=DAGK5;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   DGKG_HUMAN              Reviewed;         791 AA.
AC   P49619; B2RAH4; Q2M1H4; Q5FWG1;
DE   RecName: Full=Diacylglycerol kinase gamma;
DE            Short=DAG kinase gamma;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase gamma;
DE            Short=DGK-gamma;
GN   Name=DGKG; Synonyms=DAGK3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; TAS:ProtInc.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   DGKH_HUMAN              Reviewed;        1220 AA.
AC   Q86XP1; A2A2W7; A6NFX7; B4DZ34; Q5VZW0; Q6PI56; Q86XP2; Q8N3N0;
AC   Q8N7J9;
DE   RecName: Full=Diacylglycerol kinase eta;
DE            Short=DAG kinase eta;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase eta;
DE            Short=DGK-eta;
GN   Name=DGKH;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IMP:UniProtKB.
//
ID   DGKK_HUMAN              Reviewed;        1271 AA.
AC   Q5KSL6; B2RP91;
DE   RecName: Full=Diacylglycerol kinase kappa;
DE            Short=DAG kinase kappa;
DE            EC=2.7.1.107;
DE   AltName: Full=142 kDa diacylglycerol kinase;
DE   AltName: Full=Diglyceride kinase kappa;
DE            Short=DGK-kappa;
GN   Name=DGKK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0046339; P:diacylglycerol metabolic process; IDA:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:HGNC.
//
ID   DGKI_HUMAN              Reviewed;        1065 AA.
AC   O75912; A4D1Q9; Q9NZ49;
DE   RecName: Full=Diacylglycerol kinase iota;
DE            Short=DAG kinase iota;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase iota;
DE            Short=DGK-iota;
GN   Name=DGKI;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; TAS:ProtInc.
DR   GO; GO:0005095; F:GTPase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0032317; P:regulation of Rap GTPase activity; IEA:Ensembl.
//
ID   DGKQ_HUMAN              Reviewed;         942 AA.
AC   P52824; Q6P3W4;
DE   RecName: Full=Diacylglycerol kinase theta;
DE            Short=DAG kinase theta;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase theta;
DE            Short=DGK-theta;
GN   Name=DGKQ; Synonyms=DAGK4;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IDA:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0043274; F:phospholipase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070528; P:protein kinase C signaling; IDA:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0033198; P:response to ATP; IDA:UniProtKB.
DR   GO; GO:0070493; P:thrombin receptor signaling pathway; IDA:UniProtKB.
//
ID   DGKZ_HUMAN              Reviewed;        1117 AA.
AC   Q13574; B7Z2M9; E9PPW4; G3V0F6; J3KNJ6; O00542; Q6ZVG7; Q8IVW9;
DE   RecName: Full=Diacylglycerol kinase zeta;
DE            Short=DAG kinase zeta;
DE            EC=2.7.1.107;
DE   AltName: Full=Diglyceride kinase zeta;
DE            Short=DGK-zeta;
GN   Name=DGKZ; Synonyms=DAGK6;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IDA:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR   GO; GO:0001727; F:lipid kinase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046834; P:lipid phosphorylation; IDA:GOC.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IGI:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IGI:UniProtKB.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0016310; P:phosphorylation; IDA:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   DGLA_HUMAN              Reviewed;        1042 AA.
AC   Q9Y4D2; A7E233; Q6WQJ0;
DE   RecName: Full=Sn1-specific diacylglycerol lipase alpha;
DE            Short=DGL-alpha;
DE            EC=3.1.1.-;
DE   AltName: Full=Neural stem cell-derived dendrite regulator;
GN   Name=DAGLA; Synonyms=C11orf11, KIAA0659, NSDDR;
DR   GuidetoPHARMACOLOGY; 1396; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0046340; P:diacylglycerol catabolic process; IDA:UniProtKB.
DR   GO; GO:0071926; P:endocannabinoid signaling pathway; IEA:Ensembl.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
//
ID   DGLB_HUMAN              Reviewed;         672 AA.
AC   Q8NCG7; A4D2P3; B3KV90; B4DQU0; Q6PIX3; Q8N2N2; Q8N9S1; Q8TED3;
AC   Q8WXE6;
DE   RecName: Full=Sn1-specific diacylglycerol lipase beta;
DE            Short=DGL-beta;
DE            EC=3.1.1.-;
DE   AltName: Full=KCCR13L;
GN   Name=DAGLB;
DR   GuidetoPHARMACOLOGY; 1397; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
//
ID   DGUOK_HUMAN             Reviewed;         277 AA.
AC   Q16854; P78532; Q16759; Q4ZG09; Q96BC1;
DE   RecName: Full=Deoxyguanosine kinase, mitochondrial;
DE            Short=dGK;
DE            EC=2.7.1.113;
DE   Flags: Precursor;
GN   Name=DGUOK; Synonyms=DGK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004138; F:deoxyguanosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0009157; P:deoxyribonucleoside monophosphate biosynthetic process; IDA:GOC.
DR   GO; GO:0046070; P:dGTP metabolic process; IEA:Ensembl.
DR   GO; GO:0008617; P:guanosine metabolic process; TAS:ProtInc.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; EXP:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0046122; P:purine deoxyribonucleoside metabolic process; IDA:UniProtKB.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DHAK_HUMAN              Reviewed;         575 AA.
AC   Q3LXA3; Q53EQ9; Q9BVA7; Q9H895;
DE   RecName: Full=Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing);
DE   Includes:
DE     RecName: Full=ATP-dependent dihydroxyacetone kinase;
DE              Short=DHA kinase;
DE              EC=2.7.1.28;
DE              EC=2.7.1.29;
DE     AltName: Full=Glycerone kinase;
DE     AltName: Full=Triokinase;
DE     AltName: Full=Triose kinase;
DE   Includes:
DE     RecName: Full=FAD-AMP lyase (cyclizing);
DE              EC=4.6.1.15;
DE     AltName: Full=FAD-AMP lyase (cyclic FMN forming);
DE     AltName: Full=FMN cyclase;
GN   Name=DAK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034012; F:FAD-AMP lyase (cyclizing) activity; IDA:UniProt.
DR   GO; GO:0004371; F:glycerone kinase activity; IDA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050354; F:triokinase activity; IDA:UniProt.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:UniProt.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IDA:UniProt.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045088; P:regulation of innate immune response; IDA:UniProt.
//
ID   DHAS1_HUMAN             Reviewed;          65 AA.
AC   Q9P1J3;
DE   RecName: Full=Putative uncharacterized protein DHRS4-AS1;
DE   AltName: Full=DHRS4 antisense RNA 1;
DE   AltName: Full=DHRS4 antisense gene protein 1;
GN   Name=DHRS4-AS1; Synonyms=C14orf167; ORFNames=PRO1488;
//
ID   DHB11_HUMAN             Reviewed;         300 AA.
AC   Q8NBQ5; Q96HF6; Q9UKU4;
DE   RecName: Full=Estradiol 17-beta-dehydrogenase 11;
DE            EC=1.1.1.62;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase 11;
DE            Short=17-beta-HSD 11;
DE            Short=17bHSD11;
DE            Short=17betaHSD11;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase XI;
DE            Short=17-beta-HSD XI;
DE            Short=17betaHSDXI;
DE   AltName: Full=Cutaneous T-cell lymphoma-associated antigen HD-CL-03;
DE            Short=CTCL-associated antigen HD-CL-03;
DE   AltName: Full=Dehydrogenase/reductase SDR family member 8;
DE   AltName: Full=Retinal short-chain dehydrogenase/reductase 2;
DE            Short=retSDR2;
DE   Flags: Precursor;
GN   Name=HSD17B11; Synonyms=DHRS8, PAN1B;
GN   ORFNames=PSEC0029, UNQ207/PRO233;
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016229; F:steroid dehydrogenase activity; IDA:HGNC.
DR   GO; GO:0006710; P:androgen catabolic process; IDA:HGNC.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
//
ID   DHB12_HUMAN             Reviewed;         312 AA.
AC   Q53GQ0; A8K9B0; D3DR23; Q96JU2; Q9Y6G8;
DE   RecName: Full=Estradiol 17-beta-dehydrogenase 12;
DE            EC=1.1.1.62;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase 12;
DE            Short=17-beta-HSD 12;
DE   AltName: Full=3-ketoacyl-CoA reductase;
DE            Short=KAR;
DE            EC=1.3.1.-;
GN   Name=HSD17B12;
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006703; P:estrogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   DHB13_HUMAN             Reviewed;         300 AA.
AC   Q7Z5P4; A8K9R9; Q2M1L5; Q86W22; Q86W23;
DE   RecName: Full=17-beta-hydroxysteroid dehydrogenase 13;
DE            Short=17-beta-HSD 13;
DE            EC=1.1.-.-;
DE   AltName: Full=Short-chain dehydrogenase/reductase 9;
DE   Flags: Precursor;
GN   Name=HSD17B13; Synonyms=SCDR9; ORFNames=HMFN0376, UNQ497/PRO1014;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHB14_HUMAN             Reviewed;         270 AA.
AC   Q9BPX1; Q9UKU3;
DE   RecName: Full=17-beta-hydroxysteroid dehydrogenase 14;
DE            Short=17-beta-HSD 14;
DE            EC=1.1.1.-;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase DHRS10;
DE   AltName: Full=Dehydrogenase/reductase SDR family member 10;
DE   AltName: Full=Retinal short-chain dehydrogenase/reductase retSDR3;
GN   Name=HSD17B14; Synonyms=DHRS10, SDR3; ORFNames=UNQ502/PRO474;
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IDA:HGNC.
DR   GO; GO:0006706; P:steroid catabolic process; IDA:HGNC.
//
ID   DHB1_HUMAN              Reviewed;         328 AA.
AC   P14061; B3KXS1; Q2M2L8;
DE   RecName: Full=Estradiol 17-beta-dehydrogenase 1;
DE            EC=1.1.1.62;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase type 1;
DE            Short=17-beta-HSD 1;
DE   AltName: Full=20 alpha-hydroxysteroid dehydrogenase;
DE            Short=20-alpha-HSD;
DE   AltName: Full=E2DH;
DE   AltName: Full=Placental 17-beta-hydroxysteroid dehydrogenase;
GN   Name=HSD17B1; Synonyms=E17KSR, EDH17B1, EDH17B2, EDHB17;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0071248; P:cellular response to metal ion; IEA:Ensembl.
DR   GO; GO:0006703; P:estrogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0008210; P:estrogen metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0061370; P:testosterone biosynthetic process; IEA:Ensembl.
//
ID   DHB2_HUMAN              Reviewed;         387 AA.
AC   P37059; B2R7T4;
DE   RecName: Full=Estradiol 17-beta-dehydrogenase 2;
DE            EC=1.1.1.62;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase type 2;
DE            Short=17-beta-HSD 2;
DE   AltName: Full=20 alpha-hydroxysteroid dehydrogenase;
DE            Short=20-alpha-HSD;
DE   AltName: Full=E2DH;
DE   AltName: Full=Microsomal 17-beta-hydroxysteroid dehydrogenase;
DE   AltName: Full=Testosterone 17-beta-dehydrogenase;
DE            EC=1.1.1.239;
GN   Name=HSD17B2; Synonyms=EDH17B2;
DR   GO; GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
//
ID   DHB3_HUMAN              Reviewed;         310 AA.
AC   P37058;
DE   RecName: Full=Testosterone 17-beta-dehydrogenase 3;
DE            EC=1.1.1.64;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase type 3;
DE            Short=17-beta-HSD 3;
DE   AltName: Full=Testicular 17-beta-hydroxysteroid dehydrogenase;
GN   Name=HSD17B3; Synonyms=EDH17B3;
DR   GO; GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:Reactome.
DR   GO; GO:0030539; P:male genitalia development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0061370; P:testosterone biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   DHB4_HUMAN              Reviewed;         736 AA.
AC   P51659; B4DNV1; B4DVS5; E9PB82; F5HE57;
DE   RecName: Full=Peroxisomal multifunctional enzyme type 2;
DE            Short=MFE-2;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase 4;
DE            Short=17-beta-HSD 4;
DE   AltName: Full=D-bifunctional protein;
DE            Short=DBP;
DE   AltName: Full=Multifunctional protein 2;
DE            Short=MPF-2;
DE   Contains:
DE     RecName: Full=(3R)-hydroxyacyl-CoA dehydrogenase;
DE              EC=1.1.1.n12;
DE   Contains:
DE     RecName: Full=Enoyl-CoA hydratase 2;
DE              EC=4.2.1.107;
DE              EC=4.2.1.119;
DE     AltName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase;
GN   Name=HSD17B4; Synonyms=EDH17B4;
DR   GO; GO:0044594; F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016508; F:long-chain-enoyl-CoA hydratase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0032934; F:sterol binding; IEA:InterPro.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0008209; P:androgen metabolic process; IDA:UniProtKB.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0036112; P:medium-chain fatty-acyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0036111; P:very long-chain fatty-acyl-CoA metabolic process; IDA:UniProtKB.
//
ID   DHB7_HUMAN              Reviewed;         341 AA.
AC   P56937; Q5T246; Q7Z4V9; Q8WWS2; Q9UF00;
DE   RecName: Full=3-keto-steroid reductase;
DE            EC=1.1.1.270;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase 7;
DE            Short=17-beta-HSD 7;
DE   AltName: Full=Estradiol 17-beta-dehydrogenase 7;
DE            EC=1.1.1.62;
GN   Name=HSD17B7; ORFNames=UNQ2563/PRO6243;
DR   GO; GO:0000253; F:3-keto sterol reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006703; P:estrogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DHB8_HUMAN              Reviewed;         261 AA.
AC   Q92506; A6NLX7; Q5STP7; Q9UIQ1;
DE   RecName: Full=Estradiol 17-beta-dehydrogenase 8;
DE            EC=1.1.1.62;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase 8;
DE            Short=17-beta-HSD 8;
DE   AltName: Full=3-oxoacyl-[acyl-carrier-protein] reductase;
DE            EC=1.1.1.-;
DE   AltName: Full=Protein Ke6;
DE            Short=Ke-6;
DE   AltName: Full=Really interesting new gene 2 protein;
DE   AltName: Full=Testosterone 17-beta-dehydrogenase 8;
DE            EC=1.1.1.239;
GN   Name=HSD17B8; Synonyms=FABGL, HKE6, RING2;
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0006703; P:estrogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   DHC24_HUMAN             Reviewed;         516 AA.
AC   Q15392; D3DQ51; Q9HBA8;
DE   RecName: Full=Delta(24)-sterol reductase;
DE            EC=1.3.1.72;
DE   AltName: Full=24-dehydrocholesterol reductase;
DE   AltName: Full=3-beta-hydroxysterol delta-24-reductase;
DE   AltName: Full=Diminuto/dwarf1 homolog;
DE   AltName: Full=Seladin-1;
DE   Flags: Precursor;
GN   Name=DHCR24; Synonyms=KIAA0018;
DR   GO; GO:0050614; F:delta24-sterol reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IDA:MGI.
DR   GO; GO:0042605; F:peptide antigen binding; IPI:UniProtKB.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; NAS:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0031639; P:plasminogen activation; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:1901214; P:regulation of neuron death; NAS:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEP:UniProtKB.
DR   GO; GO:0043588; P:skin development; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009888; P:tissue development; IMP:UniProtKB.
//
ID   DHCR7_HUMAN             Reviewed;         475 AA.
AC   Q9UBM7; B2R6Z2; O60492; O60717;
DE   RecName: Full=7-dehydrocholesterol reductase;
DE            Short=7-DHC reductase;
DE            EC=1.3.1.21;
DE   AltName: Full=Putative sterol reductase SR-2;
DE   AltName: Full=Sterol Delta(7)-reductase;
GN   Name=DHCR7; Synonyms=D7SR;
DR   GO; GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045540; P:regulation of cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DHDDS_HUMAN             Reviewed;         333 AA.
AC   Q86SQ9; B7Z4B9; B7ZB20; D3DPK7; D3DPK8; D3DPK9; E9KL43; Q5T0A4;
AC   Q8NE90; Q9BTG5; Q9BTK3; Q9H905;
DE   RecName: Full=Dehydrodolichyl diphosphate synthase;
DE            Short=Dedol-PP synthase;
DE            EC=2.5.1.-;
DE   AltName: Full=Cis-isoprenyltransferase;
DE            Short=CIT;
DE            Short=Cis-IPTase;
DE   AltName: Full=Epididymis tissue protein Li 189m;
GN   Name=DHDDS; Synonyms=HDS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006489; P:dolichyl diphosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   DHDH_HUMAN              Reviewed;         334 AA.
AC   Q9UQ10;
DE   RecName: Full=Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase;
DE            EC=1.3.1.20;
DE   AltName: Full=D-xylose 1-dehydrogenase;
DE   AltName: Full=D-xylose-NADP dehydrogenase;
DE            EC=1.1.1.179;
DE   AltName: Full=Dimeric dihydrodiol dehydrogenase;
DE   AltName: Full=Hum2DD;
GN   Name=DHDH; Synonyms=2DD;
DR   GO; GO:0047837; F:D-xylose 1-dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0008746; F:NAD(P)+ transhydrogenase activity; TAS:ProtInc.
DR   GO; GO:0047115; F:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0042843; P:D-xylose catabolic process; IEA:Ensembl.
//
ID   DHE3_HUMAN              Reviewed;         558 AA.
AC   P00367; Q5TBU3;
DE   RecName: Full=Glutamate dehydrogenase 1, mitochondrial;
DE            Short=GDH 1;
DE            EC=1.4.1.3;
DE   Flags: Precursor;
GN   Name=GLUD1; Synonyms=GLUD;
DR   GO; GO:0043531; F:ADP binding; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0004353; F:glutamate dehydrogenase [NAD(P)+] activity; IDA:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; TAS:BHF-UCL.
DR   GO; GO:0070728; F:leucine binding; IDA:BHF-UCL.
DR   GO; GO:0070403; F:NAD+ binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006538; P:glutamate catabolic process; IDA:UniProtKB.
DR   GO; GO:0006541; P:glutamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0072350; P:tricarboxylic acid metabolic process; ISS:UniProtKB.
//
ID   DHE4_HUMAN              Reviewed;         558 AA.
AC   P49448; B2R8G0; Q9UDQ4;
DE   RecName: Full=Glutamate dehydrogenase 2, mitochondrial;
DE            Short=GDH 2;
DE            EC=1.4.1.3;
DE   Flags: Precursor;
GN   Name=GLUD2; Synonyms=GLUDP1;
DR   GO; GO:0043531; F:ADP binding; IDA:BHF-UCL.
DR   GO; GO:0004352; F:glutamate dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0004353; F:glutamate dehydrogenase [NAD(P)+] activity; IDA:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0070728; F:leucine binding; IDA:BHF-UCL.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006538; P:glutamate catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
//
ID   DHH_HUMAN               Reviewed;         396 AA.
AC   O43323; Q15794;
DE   RecName: Full=Desert hedgehog protein;
DE            Short=DHH;
DE   AltName: Full=HHG-3;
DE   Contains:
DE     RecName: Full=Desert hedgehog protein N-product;
DE   Contains:
DE     RecName: Full=Desert hedgehog protein C-product;
DE   Flags: Precursor;
GN   Name=DHH;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:InterPro.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   DHI1L_HUMAN             Reviewed;         315 AA.
AC   Q7Z5J1; Q05D45; Q52LF4; Q7Z5I9; Q7Z5J0; Q7Z5P5; Q7Z5P6; Q7Z5P7;
AC   Q7Z5P8;
DE   RecName: Full=Hydroxysteroid 11-beta-dehydrogenase 1-like protein;
DE            EC=1.1.1.-;
DE   AltName: Full=11-beta-hydroxysteroid dehydrogenase type 3;
DE            Short=11-DH3;
DE            Short=11-beta-HSD3;
DE   AltName: Full=Short-chain dehydrogenase/reductase 10;
DE   Flags: Precursor;
GN   Name=HSD11B1L; Synonyms=HSD3, SCDR10;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHI1_HUMAN              Reviewed;         292 AA.
AC   P28845; B2R9Z1; D3DT89;
DE   RecName: Full=Corticosteroid 11-beta-dehydrogenase isozyme 1;
DE            EC=1.1.1.146;
DE   AltName: Full=11-beta-hydroxysteroid dehydrogenase 1;
DE            Short=11-DH;
DE            Short=11-beta-HSD1;
GN   Name=HSD11B1; Synonyms=HSD11, HSD11L;
DR   GuidetoPHARMACOLOGY; 2763; -.
DR   GO; GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; TAS:Reactome.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   DHI2_HUMAN              Reviewed;         405 AA.
AC   P80365; A7LB28; C5HTY7; Q13194; Q6P2G9; Q8N439; Q96QN8; Q9UC50;
AC   Q9UC51; Q9UCW5; Q9UCW6; Q9UCW7; Q9UCW8;
DE   RecName: Full=Corticosteroid 11-beta-dehydrogenase isozyme 2;
DE            EC=1.1.1.-;
DE   AltName: Full=11-beta-hydroxysteroid dehydrogenase type 2;
DE            Short=11-DH2;
DE            Short=11-beta-HSD2;
DE   AltName: Full=11-beta-hydroxysteroid dehydrogenase type II;
DE            Short=-HSD11 type II;
DE   AltName: Full=NAD-dependent 11-beta-hydroxysteroid dehydrogenase;
DE            Short=11-beta-HSD;
GN   Name=HSD11B2; Synonyms=HSD11K;
DR   GO; GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity; IEA:Ensembl.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0005496; F:steroid binding; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006704; P:glucocorticoid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0002017; P:regulation of blood volume by renal aldosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   DHPR_HUMAN              Reviewed;         244 AA.
AC   P09417; A8K158; B3KW71; Q53F52; Q9H3M5;
DE   RecName: Full=Dihydropteridine reductase;
DE            EC=1.5.1.34;
DE   AltName: Full=HDHPR;
DE   AltName: Full=Quinoid dihydropteridine reductase;
GN   Name=QDPR; Synonyms=DHPR;
DR   GO; GO:0004155; F:6,7-dihydropteridine reductase activity; EXP:Reactome.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0070404; F:NADH binding; IEA:Ensembl.
DR   GO; GO:0070402; F:NADPH binding; IEA:Ensembl.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0051066; P:dihydrobiopterin metabolic process; TAS:ProtInc.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0010044; P:response to aluminum ion; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:UniProtKB-KW.
//
ID   DHR11_HUMAN             Reviewed;         260 AA.
AC   Q6UWP2; B2RDZ3; Q9BUC7; Q9H674;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 11;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=DHRS11; ORFNames=UNQ836/PRO1774;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHR12_HUMAN             Reviewed;         317 AA.
AC   A0PJE2; Q96GB2; Q9H8H1;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 12;
DE            EC=1.1.-.-;
GN   Name=DHRS12;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHR13_HUMAN             Reviewed;         377 AA.
AC   Q6UX07; Q96BH7;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 13;
DE            EC=1.1.-.-;
DE   Flags: Precursor;
GN   Name=DHRS13; ORFNames=UNQ419/PRO853;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHRS1_HUMAN             Reviewed;         313 AA.
AC   Q96LJ7; D3DS71; Q8NDG3; Q96B59; Q96CQ5;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 1;
DE            EC=1.1.-.-;
GN   Name=DHRS1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHRS2_HUMAN             Reviewed;         280 AA.
AC   Q13268; D3DS54; Q53GS4; Q7Z789; Q9H2R2;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial;
DE            EC=1.1.1.-;
DE   AltName: Full=Dicarbonyl reductase HEP27;
DE   AltName: Full=Protein D;
DE   Flags: Precursor;
GN   Name=DHRS2;
DR   GO; GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
//
ID   DHRS3_HUMAN             Reviewed;         302 AA.
AC   O75911; B2R7F3; Q5VUY3; Q6UY38; Q9BUC8;
DE   RecName: Full=Short-chain dehydrogenase/reductase 3;
DE            EC=1.1.1.300;
DE   AltName: Full=DD83.1;
DE   AltName: Full=Retinal short-chain dehydrogenase/reductase 1;
DE            Short=retSDR1;
GN   Name=DHRS3; ORFNames=UNQ2424/PRO4983;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; TAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   DHRS4_HUMAN             Reviewed;         278 AA.
AC   Q9BTZ2; B2RB10; B7WNS9; D3YTB8; E2QRL8; O95162; Q20CR0; Q2LC19;
AC   Q2LE81; Q58IU4; Q6E0Y1; Q6UWU3; Q71UQ6; Q8TD03; Q9H3N5; Q9NV08;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 4;
DE            EC=1.1.1.184;
DE   AltName: Full=NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase;
DE            Short=CR;
DE            Short=PHCR;
DE   AltName: Full=NADPH-dependent retinol dehydrogenase/reductase;
DE            Short=NRDR;
DE            Short=humNRDR;
DE   AltName: Full=Peroxisomal short-chain alcohol dehydrogenase;
DE            Short=PSCD;
DE   AltName: Full=SCAD-SRL;
DE   AltName: Full=Short-chain dehydrogenase/reductase family member 4;
GN   Name=DHRS4; ORFNames=UNQ851/PRO1800;
DR   GO; GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.
DR   GO; GO:0018455; F:alcohol dehydrogenase [NAD(P)+] activity; IDA:UniProtKB.
DR   GO; GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.
DR   GO; GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0008202; P:steroid metabolic process; IDA:UniProtKB.
//
ID   DHRS7_HUMAN             Reviewed;         339 AA.
AC   Q9Y394; B2R896; Q9UKU2;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 7;
DE            EC=1.1.-.-;
DE   AltName: Full=Retinal short-chain dehydrogenase/reductase 4;
DE            Short=retSDR4;
DE   Flags: Precursor;
GN   Name=DHRS7; Synonyms=DHRS7A, RETSDR4; ORFNames=CGI-86, UNQ285/PRO3448;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHRS9_HUMAN             Reviewed;         319 AA.
AC   Q9BPW9; B7Z416; D3DPC1; Q5RKX1; Q9NRA9; Q9NRB0;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 9;
DE            EC=1.1.-.-;
DE   AltName: Full=3-alpha hydroxysteroid dehydrogenase;
DE            Short=3-alpha-HSD;
DE   AltName: Full=NADP-dependent retinol dehydrogenase/reductase;
DE   AltName: Full=RDH-E2;
DE   AltName: Full=RDHL;
DE   AltName: Full=Short-chain dehydrogenase/reductase retSDR8;
DE   AltName: Full=Tracheobronchial epithelial cell-specific retinol dehydrogenase;
DE            Short=RDH-TBE;
DE   Flags: Precursor;
GN   Name=DHRS9; ORFNames=UNQ835/PRO1773;
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD) activity; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0016854; F:racemase and epimerase activity; NAS:UniProtKB.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0042904; P:9-cis-retinoic acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0042448; P:progesterone metabolic process; IDA:UniProtKB.
DR   GO; GO:0042572; P:retinol metabolic process; NAS:UniProtKB.
//
ID   DHRSX_HUMAN             Reviewed;         330 AA.
AC   Q8N5I4; Q6UWC7; Q8WUS4; Q96GR8; Q9NTF6;
DE   RecName: Full=Dehydrogenase/reductase SDR family member on chromosome X;
DE            EC=1.1.-.-;
DE   AltName: Full=DHRSXY;
DE   Flags: Precursor;
GN   Name=DHRSX; Synonyms=CXorf11, DHRS5X; ORFNames=UNQ6508/PRO21433;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DHSD_HUMAN              Reviewed;         159 AA.
AC   O14521; A6ND90; B3KQQ8; E9PIC0; E9PIG3; E9PQI9; Q53XW5; Q6IRW2;
DE   RecName: Full=Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial;
DE            Short=CybS;
DE   AltName: Full=CII-4;
DE   AltName: Full=QPs3;
DE   AltName: Full=Succinate dehydrogenase complex subunit D;
DE   AltName: Full=Succinate-ubiquinone oxidoreductase cytochrome b small subunit;
DE   AltName: Full=Succinate-ubiquinone reductase membrane anchor subunit;
DE   Flags: Precursor;
GN   Name=SDHD; Synonyms=SDH4;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000104; F:succinate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0048039; F:ubiquinone binding; ISS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IDA:UniProtKB.
//
ID   DHSO_HUMAN              Reviewed;         357 AA.
AC   Q00796; B2R655; J3JZZ5; Q16682; Q9UMD6;
DE   RecName: Full=Sorbitol dehydrogenase;
DE            EC=1.1.1.14;
DE   AltName: Full=L-iditol 2-dehydrogenase;
GN   Name=SORD;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0003939; F:L-iditol 2-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0046370; P:fructose biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:UniProtKB.
DR   GO; GO:0051160; P:L-xylitol catabolic process; IDA:UniProtKB.
DR   GO; GO:0051164; P:L-xylitol metabolic process; IDA:UniProtKB.
DR   GO; GO:0006062; P:sorbitol catabolic process; IDA:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; ISS:UniProtKB.
//
ID   DHTK1_HUMAN             Reviewed;         919 AA.
AC   Q96HY7; Q68CU5; Q9BUM8; Q9HCE2;
DE   RecName: Full=Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial;
DE            EC=1.2.4.2;
DE   AltName: Full=Dehydrogenase E1 and transketolase domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=DHTKD1; Synonyms=KIAA1630;
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IMP:UniProtKB.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
//
ID   DHX15_HUMAN             Reviewed;         795 AA.
AC   O43143; Q9NQT7;
DE   RecName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase #46;
DE   AltName: Full=DEAH box protein 15;
GN   Name=DHX15; Synonyms=DBP1, DDX15;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   DHX16_HUMAN             Reviewed;        1041 AA.
AC   O60231; O60322; Q5JP45; Q969X7; Q96QC1;
DE   RecName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase #3;
DE   AltName: Full=DEAH-box protein 16;
GN   Name=DHX16; Synonyms=DBP2, DDX16, KIAA0577;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   DHX29_HUMAN             Reviewed;        1369 AA.
AC   Q7Z478; O75549; Q63HN0; Q63HN3; Q8IWW2; Q8N3A1; Q9UMH2;
DE   RecName: Full=ATP-dependent RNA helicase DHX29;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 29;
DE   AltName: Full=Nucleic acid helicase DDXx;
GN   Name=DHX29; Synonyms=DDX29;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
//
ID   DHX30_HUMAN             Reviewed;        1194 AA.
AC   Q7L2E3; A8K5F1; O94965; Q7Z753; Q96CH4; Q9NUQ0;
DE   RecName: Full=Putative ATP-dependent RNA helicase DHX30;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 30;
GN   Name=DHX30; Synonyms=DDX30, KIAA0890;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   DHX32_HUMAN             Reviewed;         743 AA.
AC   Q7L7V1; A8MSV2; D3DRF9; Q49AG5; Q5T3L0; Q5T3L5; Q96NY1; Q9BUN0;
AC   Q9H769; Q9NSL5; Q9NV74; Q9NVJ7;
DE   RecName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD/H box 32;
DE   AltName: Full=DEAD/H helicase-like protein 1;
DE            Short=DHLP1;
DE   AltName: Full=DEAH box protein 32;
DE   AltName: Full=HuDDX32;
GN   Name=DHX32; Synonyms=DDX32;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
//
ID   DHX33_HUMAN             Reviewed;         707 AA.
AC   Q9H6R0; B4DHF9; Q4G149; Q5CZ73; Q9H5M9;
DE   RecName: Full=Putative ATP-dependent RNA helicase DHX33;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 33;
GN   Name=DHX33; Synonyms=DDX33;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000182; F:rDNA binding; IDA:UniProtKB.
DR   GO; GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IDA:UniProtKB.
//
ID   DHX34_HUMAN             Reviewed;        1143 AA.
AC   Q14147; B4DMY8;
DE   RecName: Full=Probable ATP-dependent RNA helicase DHX34;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 34;
GN   Name=DHX34; Synonyms=DDX34, KIAA0134;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProt.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProt.
//
ID   DHX35_HUMAN             Reviewed;         703 AA.
AC   Q9H5Z1; A2RTX3; B4E0J0; F5GXM6; Q5THR0; Q9H4H7; Q9H6T6;
DE   RecName: Full=Probable ATP-dependent RNA helicase DHX35;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 35;
GN   Name=DHX35; Synonyms=C20orf15, DDX35;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   DHX36_HUMAN             Reviewed;        1008 AA.
AC   Q9H2U1; B2RB00; Q70JU3; Q8IYE5; Q9P240;
DE   RecName: Full=ATP-dependent RNA helicase DHX36;
DE            EC=3.6.4.12;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 36;
DE   AltName: Full=G4-resolvase 1;
DE            Short=G4R1;
DE   AltName: Full=MLE-like protein 1;
DE   AltName: Full=RNA helicase associated with AU-rich element ARE;
GN   Name=DHX36; Synonyms=DDX36, KIAA1488, MLEL1, RHAU;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.
DR   GO; GO:0002151; F:G-quadruplex RNA binding; IMP:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; ISS:UniProtKB.
DR   GO; GO:0032206; P:positive regulation of telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEA:Ensembl.
DR   GO; GO:0010501; P:RNA secondary structure unwinding; IDA:UniProtKB.
//
ID   DHX37_HUMAN             Reviewed;        1157 AA.
AC   Q8IY37; Q9BUI7; Q9P211;
DE   RecName: Full=Probable ATP-dependent RNA helicase DHX37;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 37;
GN   Name=DHX37; Synonyms=DDX37, KIAA1517;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   DHX40_HUMAN             Reviewed;         779 AA.
AC   Q8IX18; B3KTJ5; C9JR60; Q5JPH4; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9;
DE   RecName: Full=Probable ATP-dependent RNA helicase DHX40;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 40;
DE   AltName: Full=Protein PAD;
GN   Name=DHX40; Synonyms=DDX40; ORFNames=ARG147;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   DHX57_HUMAN             Reviewed;        1386 AA.
AC   Q6P158; A2RRC7; Q53SI4; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33;
DE   RecName: Full=Putative ATP-dependent RNA helicase DHX57;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 57;
GN   Name=DHX57;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   DHX58_HUMAN             Reviewed;         678 AA.
AC   Q96C10; Q9HAM6;
DE   RecName: Full=Probable ATP-dependent RNA helicase DHX58;
DE            EC=3.6.4.13;
DE   AltName: Full=Probable ATP-dependent helicase LGP2;
DE   AltName: Full=Protein D11Lgp2 homolog;
DE   AltName: Full=RIG-I-like receptor 3;
DE            Short=RLR-3;
DE   AltName: Full=RIG-I-like receptor LGP2;
DE            Short=RLR;
GN   Name=DHX58; Synonyms=D11LGP2E, LGP2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0045824; P:negative regulation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0039534; P:negative regulation of MDA-5 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0039536; P:negative regulation of RIG-I signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; IDA:UniProtKB.
DR   GO; GO:1900245; P:positive regulation of MDA-5 signaling pathway; ISS:UniProtKB.
DR   GO; GO:1900246; P:positive regulation of RIG-I signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; ISS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DHX8_HUMAN              Reviewed;        1220 AA.
AC   Q14562;
DE   RecName: Full=ATP-dependent RNA helicase DHX8;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 8;
DE   AltName: Full=RNA helicase HRH1;
GN   Name=DHX8; Synonyms=DDX8;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   DHX9_HUMAN              Reviewed;        1270 AA.
AC   Q08211; B2RNV4; Q05CI5; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556;
DE   RecName: Full=ATP-dependent RNA helicase A;
DE            Short=RHA;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAH box protein 9;
DE   AltName: Full=Leukophysin;
DE            Short=LKP;
DE   AltName: Full=Nuclear DNA helicase II;
DE            Short=NDH II;
GN   Name=DHX9; Synonyms=DDX9, LKP, NDH2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0070934; P:CRD-mediated mRNA stabilization; IMP:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   DHYS_HUMAN              Reviewed;         369 AA.
AC   P49366; A8K688; M0R1I5; Q13184; Q13276; Q9UDG0;
DE   RecName: Full=Deoxyhypusine synthase;
DE            Short=DHS;
DE            EC=2.5.1.46;
GN   Name=DHPS; Synonyms=DS;
DR   GO; GO:0034038; F:deoxyhypusine synthase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050983; P:deoxyhypusine biosynthetic process from spermidine; TAS:ProtInc.
DR   GO; GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   DI3L1_HUMAN             Reviewed;        1054 AA.
AC   Q8TF46; Q8N1N8; Q8WTU9; Q96CM7;
DE   RecName: Full=DIS3-like exonuclease 1;
DE            EC=3.1.13.-;
GN   Name=DIS3L; Synonyms=DIS3L1, KIAA1955;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0016075; P:rRNA catabolic process; IDA:UniProtKB.
//
ID   DI3L2_HUMAN             Reviewed;         885 AA.
AC   Q8IYB7; Q53S79; Q580W6; Q5XKH0; Q69YG5; Q6AW99; Q7Z4T6; Q8N9K9;
DE   RecName: Full=DIS3-like exonuclease 2;
DE            Short=hDIS3L2;
DE            EC=3.1.13.-;
GN   Name=DIS3L2; Synonyms=FAM6A;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004540; F:ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010587; P:miRNA catabolic process; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0051306; P:mitotic sister chromatid separation; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0000291; P:nuclear-transcribed mRNA catabolic process, exonucleolytic; IMP:UniProtKB.
DR   GO; GO:0034427; P:nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; IEA:InterPro.
DR   GO; GO:1990074; P:polyuridylation-dependent mRNA catabolic process; ISS:UniProtKB.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
//
ID   DIA1_HUMAN              Reviewed;         430 AA.
AC   Q8NDZ4; B2RCF2; B7Z1W3;
DE   RecName: Full=Deleted in autism protein 1;
DE   AltName: Full=Golgi Protein of 49 kDa;
DE            Short=GoPro49;
DE   AltName: Full=Hypoxia and AKT-induced stem cell factor;
DE            Short=HASF;
DE   Flags: Precursor;
GN   Name=C3orf58; Synonyms=DIA1;
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0014066; P:regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
//
ID   DIA1R_HUMAN             Reviewed;         433 AA.
AC   Q9H7Y0; A8MUU5; B2RPN7; Q6UWJ5;
DE   RecName: Full=Deleted in autism-related protein 1;
DE   Flags: Precursor;
GN   Name=CXorf36; Synonyms=DIA1R; ORFNames=UNQ1862/PRO3743;
//
ID   DIAC_HUMAN              Reviewed;         385 AA.
AC   Q01459; Q5VX50;
DE   RecName: Full=Di-N-acetylchitobiase;
DE            EC=3.2.1.-;
DE   Flags: Precursor;
GN   Name=CTBS; Synonyms=CTB;
DR   GO; GO:0004568; F:chitinase activity; IEA:Ensembl.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:Ensembl.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IEA:Ensembl.
//
ID   DIAP1_HUMAN             Reviewed;        1272 AA.
AC   O60610; A6NF18; B7ZKW2; E9PEZ2; Q17RN4; Q59FH8; Q9UC76;
DE   RecName: Full=Protein diaphanous homolog 1;
DE   AltName: Full=Diaphanous-related formin-1;
DE            Short=DRF1;
GN   Name=DIAPH1; Synonyms=DIAP1;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; NAS:ProtInc.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0071420; P:cellular response to histamine; IMP:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0035372; P:protein localization to microtubule; IMP:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   DIAP2_HUMAN             Reviewed;        1101 AA.
AC   O60879; A6NG19; O60878; Q8WX06; Q8WX48; Q9UJL2;
DE   RecName: Full=Protein diaphanous homolog 2;
DE   AltName: Full=Diaphanous-related formin-2;
DE            Short=DRF2;
GN   Name=DIAPH2; Synonyms=DIA;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0000910; P:cytokinesis; TAS:ProtInc.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
//
ID   DIAP3_HUMAN             Reviewed;        1193 AA.
AC   Q9NSV4; A2A3B8; A2A3B9; A2A3C0; Q18P99; Q18PA0; Q18PA1; Q2KPB6;
AC   Q3ZK23; Q5JTP8; Q5T2S7; Q5XKF6; Q6MZF0; Q6NUP0; Q86VS4; Q8NAV4;
DE   RecName: Full=Protein diaphanous homolog 3;
DE   AltName: Full=Diaphanous-related formin-3;
DE            Short=DRF3;
DE   AltName: Full=MDia2;
GN   Name=DIAPH3; Synonyms=DIAP3;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   DICER_HUMAN             Reviewed;        1922 AA.
AC   Q9UPY3; A7E2D3; E0AD28; O95943; Q9UQ02;
DE   RecName: Full=Endoribonuclease Dicer;
DE            EC=3.1.26.3;
DE   AltName: Full=Helicase with RNase motif;
DE            Short=Helicase MOI;
GN   Name=DICER1; Synonyms=DICER, HERNA, KIAA0928;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035198; F:miRNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004525; F:ribonuclease III activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071335; P:hair follicle cell proliferation; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0060119; P:inner ear receptor cell development; IEA:Ensembl.
DR   GO; GO:0060576; P:intestinal epithelial cell development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0021675; P:nerve development; ISS:BHF-UCL.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0021889; P:olfactory bulb interneuron differentiation; IEA:Ensembl.
DR   GO; GO:0032290; P:peripheral nervous system myelin formation; ISS:BHF-UCL.
DR   GO; GO:2000630; P:positive regulation of miRNA metabolic process; IEA:Ensembl.
DR   GO; GO:0031643; P:positive regulation of myelination; ISS:BHF-UCL.
DR   GO; GO:0014040; P:positive regulation of Schwann cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0031054; P:pre-miRNA processing; IDA:UniProtKB.
DR   GO; GO:0035196; P:production of miRNAs involved in gene silencing by miRNA; ISS:BHF-UCL.
DR   GO; GO:0030422; P:production of siRNA involved in RNA interference; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0070173; P:regulation of enamel mineralization; IEA:Ensembl.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048713; P:regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045069; P:regulation of viral genome replication; IEA:Ensembl.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051225; P:spindle assembly; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; IMP:UniProtKB.
DR   GO; GO:0010070; P:zygote asymmetric cell division; IEA:Ensembl.
//
ID   DIC_HUMAN               Reviewed;         287 AA.
AC   Q9UBX3; Q542Z3; Q96BA1; Q96IP1;
DE   RecName: Full=Mitochondrial dicarboxylate carrier;
DE   AltName: Full=Solute carrier family 25 member 10;
GN   Name=SLC25A10; Synonyms=DIC;
DR   GO; GO:0005310; F:dicarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006835; P:dicarboxylic acid transport; TAS:ProtInc.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   DIDO1_HUMAN             Reviewed;        2240 AA.
AC   Q9BTC0; A8MY65; B9EH82; E1P5I1; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1;
AC   Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BW03; Q9H4G6; Q9H4G7;
AC   Q9NTU8; Q9NUM8; Q9UFB6;
DE   RecName: Full=Death-inducer obliterator 1;
DE            Short=DIO-1;
DE            Short=hDido1;
DE   AltName: Full=Death-associated transcription factor 1;
DE            Short=DATF-1;
GN   Name=DIDO1; Synonyms=C20orf158, DATF1, KIAA0333;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   DIEXF_HUMAN             Reviewed;         756 AA.
AC   Q68CQ4; O75992; Q4VY00; Q63HL9;
DE   RecName: Full=Digestive organ expansion factor homolog;
GN   Name=DIEXF; Synonyms=C1orf107, DEF;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   DIM1_HUMAN              Reviewed;         313 AA.
AC   Q9UNQ2; O76025; Q9BU77; Q9UES1;
DE   RecName: Full=Probable dimethyladenosine transferase;
DE            EC=2.1.1.183;
DE   AltName: Full=DIM1 dimethyladenosine transferase 1 homolog;
DE   AltName: Full=DIM1 dimethyladenosine transferase 1-like;
DE   AltName: Full=Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase;
DE   AltName: Full=Probable 18S rRNA dimethylase;
DE   AltName: Full=Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase;
GN   Name=DIMT1; Synonyms=DIMT1L; ORFNames=HUSSY-05;
DR   GO; GO:0052909; F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
//
ID   DIP2A_HUMAN             Reviewed;        1571 AA.
AC   Q14689; A6P4T3; B4E0F0; E7EMA5; Q8IVA3; Q8N4S2; Q8TD89; Q96ML9;
DE   RecName: Full=Disco-interacting protein 2 homolog A;
DE            Short=DIP2 homolog A;
GN   Name=DIP2A; Synonyms=C21orf106, DIP2, KIAA0184;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IMP:UniProt.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProt.
//
ID   DIP2B_HUMAN             Reviewed;        1576 AA.
AC   Q9P265; Q6B011; Q8N1L5; Q8NB38;
DE   RecName: Full=Disco-interacting protein 2 homolog B;
DE            Short=DIP2 homolog B;
GN   Name=DIP2B; Synonyms=KIAA1463;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   DIP2C_HUMAN             Reviewed;        1556 AA.
AC   Q9Y2E4; Q5SS78;
DE   RecName: Full=Disco-interacting protein 2 homolog C;
DE            Short=DIP2 homolog C;
GN   Name=DIP2C; Synonyms=KIAA0934;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   DIRA2_HUMAN             Reviewed;         199 AA.
AC   Q96HU8; B3KVM2;
DE   RecName: Full=GTP-binding protein Di-Ras2;
DE   AltName: Full=Distinct subgroup of the Ras family member 2;
DE   Flags: Precursor;
GN   Name=DIRAS2;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DIRA1_HUMAN             Reviewed;         198 AA.
AC   O95057;
DE   RecName: Full=GTP-binding protein Di-Ras1;
DE   AltName: Full=Distinct subgroup of the Ras family member 1;
DE   AltName: Full=Ras-related inhibitor of cell growth;
DE            Short=Rig;
DE   AltName: Full=Small GTP-binding tumor suppressor 1;
DE   Flags: Precursor;
GN   Name=DIRAS1; Synonyms=GBTS1, RIG;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProt.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProt.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DIRA3_HUMAN             Reviewed;         229 AA.
AC   O95661; B3KMP3;
DE   RecName: Full=GTP-binding protein Di-Ras3;
DE   AltName: Full=Distinct subgroup of the Ras family member 3;
DE   AltName: Full=Rho-related GTP-binding protein RhoI;
DE   Flags: Precursor;
GN   Name=DIRAS3; Synonyms=ARHI, NOEY2, RHOI;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   DIRC1_HUMAN             Reviewed;         104 AA.
AC   Q969H9; Q08AK1;
DE   RecName: Full=Disrupted in renal carcinoma protein 1;
DE   AltName: Full=Disrupted in renal cancer protein;
GN   Name=DIRC1;
//
ID   DIRC2_HUMAN             Reviewed;         478 AA.
AC   Q96SL1; A8K561; Q8NBX9;
DE   RecName: Full=Disrupted in renal carcinoma protein 2;
DE   AltName: Full=Disrupted in renal cancer protein 2;
GN   Name=DIRC2;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DISC1_HUMAN             Reviewed;         854 AA.
AC   Q9NRI5; A6NLH2; C4P091; C4P095; C4P0A1; C4P0A3; C4P0B3; C4P0B6;
AC   C4P0C1; C9J6D0; O75045; Q5VT44; Q5VT45; Q8IXJ0; Q8IXJ1; Q9BX19;
AC   Q9NRI3; Q9NRI4;
DE   RecName: Full=Disrupted in schizophrenia 1 protein;
GN   Name=DISC1; Synonyms=KIAA0457;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IMP:UniProtKB.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IGI:UniProtKB.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IGI:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0090128; P:regulation of synapse maturation; IEA:Ensembl.
DR   GO; GO:0031929; P:TOR signaling; IEA:Ensembl.
//
ID   DISP1_HUMAN             Reviewed;        1524 AA.
AC   Q96F81; Q8N7C2; Q96I92; Q9H698; Q9H8H9; Q9UFA2;
DE   RecName: Full=Protein dispatched homolog 1;
GN   Name=DISP1; Synonyms=DISPA;
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0015197; F:peptide transporter activity; ISS:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0060539; P:diaphragm development; IMP:UniProtKB.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0007225; P:patched ligand maturation; IEA:Ensembl.
DR   GO; GO:0015833; P:peptide transport; ISS:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; ISS:UniProtKB.
DR   GO; GO:0050708; P:regulation of protein secretion; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   DISP2_HUMAN             Reviewed;        1401 AA.
AC   A7MBM2; Q6AHW3; Q9C0C1;
DE   RecName: Full=Protein dispatched homolog 2;
GN   Name=DISP2; Synonyms=DISPB, KIAA1742;
DR   GO; GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB.
//
ID   DIXC1_HUMAN             Reviewed;         683 AA.
AC   Q155Q3; A1A5D8; E9PRV4; Q6P2J8; Q6PIK4; Q86SR7; Q8IVY4; Q96N69;
AC   Q9C0C8;
DE   RecName: Full=Dixin;
DE   AltName: Full=Coiled-coil protein DIX1;
DE            Short=Coiled-coil-DIX1;
DE   AltName: Full=DIX domain-containing protein 1;
GN   Name=DIXDC1; Synonyms=CCD1, KIAA1735;
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0043010; P:camera-type eye development; IBA:RefGenome.
DR   GO; GO:0021695; P:cerebellar cortex development; IBA:RefGenome.
DR   GO; GO:0030900; P:forebrain development; IBA:RefGenome.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IBA:RefGenome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046328; P:regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DJB11_HUMAN             Reviewed;         358 AA.
AC   Q9UBS4; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6;
DE   RecName: Full=DnaJ homolog subfamily B member 11;
DE   AltName: Full=APOBEC1-binding protein 2;
DE            Short=ABBP-2;
DE   AltName: Full=DnaJ protein homolog 9;
DE   AltName: Full=ER-associated DNAJ;
DE   AltName: Full=ER-associated Hsp40 co-chaperone;
DE   AltName: Full=Endoplasmic reticulum DNA J domain-containing protein 3;
DE            Short=ER-resident protein ERdj3;
DE            Short=ERdj3;
DE            Short=ERj3p;
DE   AltName: Full=HEDJ;
DE   AltName: Full=Human DnaJ protein 9;
DE            Short=hDj-9;
DE   AltName: Full=PWP1-interacting protein 4;
DE   Flags: Precursor;
GN   Name=DNAJB11; Synonyms=EDJ, ERJ3, HDJ9;
GN   ORFNames=PSEC0121, UNQ537/PRO1080;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0016556; P:mRNA modification; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   DJB12_HUMAN             Reviewed;         375 AA.
AC   Q9NXW2; B7Z7I3; Q9H6H0;
DE   RecName: Full=DnaJ homolog subfamily B member 12;
GN   Name=DNAJB12;
//
ID   DJB13_HUMAN             Reviewed;         316 AA.
AC   P59910; B3LEP4; Q8IZW5;
DE   RecName: Full=DnaJ homolog subfamily B member 13;
DE   AltName: Full=Testis and spermatogenesis cell-related protein 6;
DE   AltName: Full=Testis spermatocyte apoptosis-related gene 6 protein;
DE   AltName: Full=Testis spermatogenesis apoptosis-related gene 3 protein;
DE   AltName: Full=Testis spermatogenesis apoptosis-related gene 6 protein;
GN   Name=DNAJB13; Synonyms=TSARG3, TSARG6;
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   DJB14_HUMAN             Reviewed;         379 AA.
AC   Q8TBM8; Q6UXN1; Q7Z3P0; Q86TA7; Q86TM0; Q9GZU9;
DE   RecName: Full=DnaJ homolog subfamily B member 14;
GN   Name=DNAJB14; ORFNames=UNQ9427/PRO34683;
//
ID   DJC10_HUMAN             Reviewed;         793 AA.
AC   Q8IXB1; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8NC82;
AC   Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6;
DE   RecName: Full=DnaJ homolog subfamily C member 10;
DE            EC=1.8.4.-;
DE   AltName: Full=Endoplasmic reticulum DNA J domain-containing protein 5;
DE            Short=ER-resident protein ERdj5;
DE            Short=ERdj5;
DE   AltName: Full=Macrothioredoxin;
DE            Short=MTHr;
DE   Flags: Precursor;
GN   Name=DNAJC10; Synonyms=ERDJ5; ORFNames=UNQ495/PRO1012;
DR   GO; GO:0001671; F:ATPase activator activity; ISS:UniProtKB.
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0051087; F:chaperone binding; IDA:UniProtKB.
DR   GO; GO:0015036; F:disulfide oxidoreductase activity; ISS:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.
DR   GO; GO:0051787; F:misfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; ISS:UniProtKB.
DR   GO; GO:0034975; P:protein folding in endoplasmic reticulum; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
//
ID   DJC11_HUMAN             Reviewed;         559 AA.
AC   Q9NVH1; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7;
DE   RecName: Full=DnaJ homolog subfamily C member 11;
GN   Name=DNAJC11;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   DJC12_HUMAN             Reviewed;         198 AA.
AC   Q9UKB3; Q5JVQ1; Q9UKB2;
DE   RecName: Full=DnaJ homolog subfamily C member 12;
DE   AltName: Full=J domain-containing protein 1;
GN   Name=DNAJC12; Synonyms=JDP1;
//
ID   DJC13_HUMAN             Reviewed;        2243 AA.
AC   O75165; Q3L0T1; Q6PI82; Q6UJ77; Q6ZSW1; Q6ZUT5; Q86XG3; Q96DC1;
AC   Q9BWK9;
DE   RecName: Full=DnaJ homolog subfamily C member 13;
DE   AltName: Full=Required for receptor-mediated endocytosis 8;
DE            Short=RME-8;
GN   Name=DNAJC13; Synonyms=KIAA0678, RME8;
//
ID   DJC14_HUMAN             Reviewed;         702 AA.
AC   Q6Y2X3; A5YM67; Q17RY2; Q66K17; Q96N59; Q96T63;
DE   RecName: Full=DnaJ homolog subfamily C member 14;
DE   AltName: Full=DnaJ protein homolog 3;
DE   AltName: Full=Dopamine receptor-interacting protein of 78 kDa;
DE            Short=DRIP78;
DE   AltName: Full=Human DnaJ protein 3;
DE            Short=hDj-3;
GN   Name=DNAJC14; Synonyms=DRIP78, HDJ3;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DJC15_HUMAN             Reviewed;         150 AA.
AC   Q9Y5T4; B2R4L0; Q5T219; Q6X963;
DE   RecName: Full=DnaJ homolog subfamily C member 15;
DE   AltName: Full=Cell growth-inhibiting gene 22 protein;
DE   AltName: Full=Methylation-controlled J protein;
DE            Short=MCJ;
GN   Name=DNAJC15; Synonyms=DNAJD1; ORFNames=GIG22, HSD18;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DJC16_HUMAN             Reviewed;         782 AA.
AC   Q9Y2G8; Q68D57; Q86X32; Q8N5P4;
DE   RecName: Full=DnaJ homolog subfamily C member 16;
DE   Flags: Precursor;
GN   Name=DNAJC16; Synonyms=KIAA0962;
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   DJC17_HUMAN             Reviewed;         304 AA.
AC   Q9NVM6;
DE   RecName: Full=DnaJ homolog subfamily C member 17;
GN   Name=DNAJC17;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   DJC18_HUMAN             Reviewed;         358 AA.
AC   Q9H819;
DE   RecName: Full=DnaJ homolog subfamily C member 18;
GN   Name=DNAJC18;
//
ID   DJC21_HUMAN             Reviewed;         531 AA.
AC   Q5F1R6; Q3B7J9; Q6P086; Q6ZS43; Q86VC6;
DE   RecName: Full=DnaJ homolog subfamily C member 21;
DE   AltName: Full=DnaJ homolog subfamily A member 5;
DE   AltName: Full=Protein GS3;
GN   Name=DNAJC21; Synonyms=DNAJA5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   DJC22_HUMAN             Reviewed;         341 AA.
AC   Q8N4W6; B3KP54;
DE   RecName: Full=DnaJ homolog subfamily C member 22;
GN   Name=DNAJC22;
//
ID   DJC24_HUMAN             Reviewed;         148 AA.
AC   Q6P3W2; A8K0V0; B1ALC1;
DE   RecName: Full=DnaJ homolog subfamily C member 24;
DE   AltName: Full=CSL-type zinc finger-containing protein 3;
DE   AltName: Full=Diphthamide biosynthesis protein 4;
GN   Name=DNAJC24; Synonyms=DPH4, ZCSL3;
DR   GO; GO:0001671; F:ATPase activator activity; IDA:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; TAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.
//
ID   DJC25_HUMAN             Reviewed;         360 AA.
AC   Q9H1X3; Q5QTD8; Q96BN9;
DE   RecName: Full=DnaJ homolog subfamily C member 25;
GN   Name=DNAJC25;
//
ID   DJC27_HUMAN             Reviewed;         273 AA.
AC   Q9NZQ0; Q5JV88; Q86Y24;
DE   RecName: Full=DnaJ homolog subfamily C member 27;
DE   AltName: Full=Rab and DnaJ domain-containing protein;
GN   Name=DNAJC27; Synonyms=RABJS, RBJ;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DJC28_HUMAN             Reviewed;         388 AA.
AC   Q9NX36; D3DSF2;
DE   RecName: Full=DnaJ homolog subfamily C member 28;
GN   Name=DNAJC28; Synonyms=C21orf55, C21orf78;
//
ID   DJC30_HUMAN             Reviewed;         226 AA.
AC   Q96LL9; Q9BSG8;
DE   RecName: Full=DnaJ homolog subfamily C member 30;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 18 protein;
GN   Name=DNAJC30; Synonyms=WBSCR18;
//
ID   DKC1_HUMAN              Reviewed;         514 AA.
AC   O60832; F5BSB3; O43845; Q96G67; Q9Y505;
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit 4;
DE            EC=5.4.99.-;
DE   AltName: Full=CBF5 homolog;
DE   AltName: Full=Dyskerin;
DE   AltName: Full=Nopp140-associated protein of 57 kDa;
DE   AltName: Full=Nucleolar protein NAP57;
DE   AltName: Full=Nucleolar protein family A member 4;
DE   AltName: Full=snoRNP protein DKC1;
GN   Name=DKC1; Synonyms=NOLA4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003720; F:telomerase activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; TAS:Reactome.
//
ID   DKK1_HUMAN              Reviewed;         266 AA.
AC   O94907; B2RC19;
DE   RecName: Full=Dickkopf-related protein 1;
DE            Short=Dickkopf-1;
DE            Short=Dkk-1;
DE            Short=hDkk-1;
DE   AltName: Full=SK;
DE   Flags: Precursor;
GN   Name=DKK1; ORFNames=UNQ492/PRO1008;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048019; F:receptor antagonist activity; IDA:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0000904; P:cell morphogenesis involved in differentiation; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001706; P:endoderm formation; IEA:Ensembl.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; IDA:GOC.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:1901296; P:negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment; IDA:BHF-UCL.
DR   GO; GO:2000726; P:negative regulation of cardiac muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0042662; P:negative regulation of mesodermal cell fate specification; IDA:BHF-UCL.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0090082; P:positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0042663; P:regulation of endodermal cell fate specification; IDA:BHF-UCL.
DR   GO; GO:0002090; P:regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IEA:Ensembl.
//
ID   DKK2_HUMAN              Reviewed;         259 AA.
AC   Q9UBU2; A0AVE9; B2R6S7; Q9UIU3;
DE   RecName: Full=Dickkopf-related protein 2;
DE            Short=Dickkopf-2;
DE            Short=Dkk-2;
DE            Short=hDkk-2;
DE   Flags: Precursor;
GN   Name=DKK2; ORFNames=UNQ682/PRO1316;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DKK4_HUMAN              Reviewed;         224 AA.
AC   Q9UBT3; Q3KNX0; Q9Y4C3;
DE   RecName: Full=Dickkopf-related protein 4;
DE            Short=Dickkopf-4;
DE            Short=Dkk-4;
DE            Short=hDkk-4;
DE   Contains:
DE     RecName: Full=Dickkopf-related protein 4 short form;
DE   Flags: Precursor;
GN   Name=DKK4;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DKK3_HUMAN              Reviewed;         350 AA.
AC   Q9UBP4; A8K1I2; D3DQW1; Q9ULB7;
DE   RecName: Full=Dickkopf-related protein 3;
DE            Short=Dickkopf-3;
DE            Short=Dkk-3;
DE            Short=hDkk-3;
DE   Flags: Precursor;
GN   Name=DKK3; Synonyms=REIC; ORFNames=UNQ258/PRO295;
DR   GO; GO:0030325; P:adrenal gland development; IEP:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0032348; P:negative regulation of aldosterone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:2000065; P:negative regulation of cortisol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DKKL1_HUMAN             Reviewed;         242 AA.
AC   Q9UK85;
DE   RecName: Full=Dickkopf-like protein 1;
DE   AltName: Full=Cancer/testis antigen 34;
DE            Short=CT34;
DE   AltName: Full=Protein soggy-1;
DE            Short=SGY-1;
DE   Flags: Precursor;
GN   Name=DKKL1; Synonyms=SGY1; ORFNames=UNQ735/PRO1429;
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   DLDH_HUMAN              Reviewed;         509 AA.
AC   P09622; B2R5X0; Q14131; Q14167; Q59EV8; Q8WTS4;
DE   RecName: Full=Dihydrolipoyl dehydrogenase, mitochondrial;
DE            EC=1.8.1.4;
DE   AltName: Full=Dihydrolipoamide dehydrogenase;
DE   AltName: Full=Glycine cleavage system L protein;
DE   Flags: Precursor;
GN   Name=DLD; Synonyms=GCSL, LAD, PHE3;
DR   GO; GO:0004148; F:dihydrolipoyl dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048240; P:sperm capacitation; IEA:Ensembl.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   DLEC1_HUMAN             Reviewed;        1755 AA.
AC   Q9Y238; Q9NSW0; Q9NTG5;
DE   RecName: Full=Deleted in lung and esophageal cancer protein 1;
DE   AltName: Full=Deleted in lung cancer protein 1;
DE            Short=DLC-1;
GN   Name=DLEC1; Synonyms=DLC1;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   DLG1_HUMAN              Reviewed;         904 AA.
AC   Q12959; A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9;
AC   E7EWL7; E9PG21; Q12958;
DE   RecName: Full=Disks large homolog 1;
DE   AltName: Full=Synapse-associated protein 97;
DE            Short=SAP-97;
DE            Short=SAP97;
DE   AltName: Full=hDlg;
GN   Name=DLG1;
DR   GO; GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc.
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0097016; F:L27 domain binding; IPI:BHF-UCL.
DR   GO; GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IDA:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0042982; P:amyloid precursor protein metabolic process; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0001935; P:endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.
DR   GO; GO:0060022; P:hard palate development; IEA:Ensembl.
DR   GO; GO:0001771; P:immunological synapse formation; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0031579; P:membrane raft organization; IEA:Ensembl.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; NAS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0030432; P:peristalsis; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IDA:BHF-UCL.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; TAS:BHF-UCL.
DR   GO; GO:0048608; P:reproductive structure development; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0002369; P:T cell cytokine production; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DLG2_HUMAN              Reviewed;         870 AA.
AC   Q15700; B7WNY8; F8W9V6; Q59G57; Q5H9Q4; Q68CQ8; Q6ZTA8;
DE   RecName: Full=Disks large homolog 2;
DE   AltName: Full=Channel-associated protein of synapse-110;
DE            Short=Chapsyn-110;
DE   AltName: Full=Postsynaptic density protein PSD-93;
GN   Name=DLG2;
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   DLG3_HUMAN              Reviewed;         817 AA.
AC   Q92796; B4E0H1; D3DVU5; Q5JUW6; Q5JUW7; Q9ULI8;
DE   RecName: Full=Disks large homolog 3;
DE   AltName: Full=Neuroendocrine-DLG;
DE   AltName: Full=Synapse-associated protein 102;
DE            Short=SAP-102;
DE            Short=SAP102;
DE   AltName: Full=XLMR;
GN   Name=DLG3; Synonyms=KIAA1232;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001736; P:establishment of planar polarity; IEA:Ensembl.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   DLG4_HUMAN              Reviewed;         724 AA.
AC   P78352; B7Z1S1; G5E939; Q92941; Q9UKK8;
DE   RecName: Full=Disks large homolog 4;
DE   AltName: Full=Postsynaptic density protein 95;
DE            Short=PSD-95;
DE   AltName: Full=Synapse-associated protein 90;
DE            Short=SAP-90;
DE            Short=SAP90;
GN   Name=DLG4; Synonyms=PSD95;
DR   GO; GO:0033130; F:acetylcholine receptor binding; ISS:BHF-UCL.
DR   GO; GO:0031697; F:beta-1 adrenergic receptor binding; ISS:BHF-UCL.
DR   GO; GO:0031748; F:D1 dopamine receptor binding; ISS:BHF-UCL.
DR   GO; GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.
DR   GO; GO:0031812; F:P2Y1 nucleotide receptor binding; ISS:BHF-UCL.
DR   GO; GO:0030165; F:PDZ domain binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; ISS:BHF-UCL.
DR   GO; GO:0019903; F:protein phosphatase binding; ISS:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045184; P:establishment of protein localization; IDA:BHF-UCL.
DR   GO; GO:0007612; P:learning; TAS:ProtInc.
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0002091; P:negative regulation of receptor internalization; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0035418; P:protein localization to synapse; IDA:BHF-UCL.
DR   GO; GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.
DR   GO; GO:2000821; P:regulation of grooming behavior; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; ISS:BHF-UCL.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016188; P:synaptic vesicle maturation; ISS:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IEA:Ensembl.
//
ID   DLG5_HUMAN              Reviewed;        1919 AA.
AC   Q8TDM6; A6H8Y3; Q149N1; Q5T1H7; Q5T1H8; Q6DKG3; Q86WC0; Q8TDM7;
AC   Q9UE73; Q9Y4E3;
DE   RecName: Full=Disks large homolog 5;
DE   AltName: Full=Discs large protein P-dlg;
DE   AltName: Full=Placenta and prostate DLG;
GN   Name=DLG5; Synonyms=KIAA0583, PDLG;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:MGI.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   DLGP1_HUMAN             Reviewed;         977 AA.
AC   O14490; A8MWN8; B2RMU8; B7WPA1; B7Z2H2; B7Z2I2; B7Z9Y4; O14489;
AC   P78335;
DE   RecName: Full=Disks large-associated protein 1;
DE            Short=DAP-1;
DE   AltName: Full=Guanylate kinase-associated protein;
DE            Short=hGKAP;
DE   AltName: Full=PSD-95/SAP90-binding protein 1;
DE   AltName: Full=SAP90/PSD-95-associated protein 1;
DE            Short=SAPAP1;
GN   Name=DLGAP1; Synonyms=DAP1, GKAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
//
ID   DLGP2_HUMAN             Reviewed;        1054 AA.
AC   Q9P1A6; A1QCF8; A1QCF9; A5D8Y2; O14488; O14664; Q9P1A7;
DE   RecName: Full=Disks large-associated protein 2;
DE            Short=DAP-2;
DE   AltName: Full=PSD-95/SAP90-binding protein 2;
DE   AltName: Full=SAP90/PSD-95-associated protein 2;
DE            Short=SAPAP2;
GN   Name=DLGAP2; Synonyms=DAP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; NAS:UniProtKB.
//
ID   DLGP3_HUMAN             Reviewed;         979 AA.
AC   O95886; Q5TDD5; Q9H3X7;
DE   RecName: Full=Disks large-associated protein 3;
DE            Short=DAP-3;
DE   AltName: Full=PSD-95/SAP90-binding protein 3;
DE   AltName: Full=SAP90/PSD-95-associated protein 3;
DE            Short=SAPAP3;
GN   Name=DLGAP3; Synonyms=DAP3;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:InterPro.
//
ID   DLGP4_HUMAN             Reviewed;         992 AA.
AC   Q9Y2H0; E1P5T5; Q5QPG4; Q5T2Y4; Q5T2Y5; Q9H137; Q9H138; Q9H1L7;
DE   RecName: Full=Disks large-associated protein 4;
DE            Short=DAP-4;
DE   AltName: Full=PSD-95/SAP90-binding protein 4;
DE   AltName: Full=SAP90/PSD-95-associated protein 4;
DE            Short=SAPAP-4;
GN   Name=DLGAP4; Synonyms=DAP4, KIAA0964, SAPAP4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:InterPro.
//
ID   DLGP5_HUMAN             Reviewed;         846 AA.
AC   Q15398; A8MTM6; B4DRM8; Q86T11; Q8NG58;
DE   RecName: Full=Disks large-associated protein 5;
DE            Short=DAP-5;
DE   AltName: Full=Discs large homolog 7;
DE   AltName: Full=Disks large-associated protein DLG7;
DE   AltName: Full=Hepatoma up-regulated protein;
DE            Short=HURP;
GN   Name=DLGAP5; Synonyms=DLG7, KIAA0008;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0007079; P:mitotic chromosome movement towards spindle pole; NAS:UniProtKB.
DR   GO; GO:0000087; P:mitotic M phase; IDA:UniProtKB.
DR   GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; NAS:UniProtKB.
//
ID   DLK1_HUMAN              Reviewed;         383 AA.
AC   P80370; P15803; Q96DW5;
DE   RecName: Full=Protein delta homolog 1;
DE            Short=DLK-1;
DE   AltName: Full=pG2;
DE   Contains:
DE     RecName: Full=Fetal antigen 1;
DE              Short=FA1;
DE   Flags: Precursor;
GN   Name=DLK1; Synonyms=DLK;
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
//
ID   DLK2_HUMAN              Reviewed;         383 AA.
AC   Q6UY11; B3KNZ7; Q5T3T8; Q9BQ54;
DE   RecName: Full=Protein delta homolog 2;
DE            Short=DLK-2;
DE   AltName: Full=Epidermal growth factor-like protein 9;
DE            Short=EGF-like protein 9;
DE   Flags: Precursor;
GN   Name=DLK2; Synonyms=EGFL9; ORFNames=UNQ2903/PRO28633;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IEA:Ensembl.
//
ID   DLL1_HUMAN              Reviewed;         723 AA.
AC   O00548; B2RAK7; Q9NU41; Q9UJV2;
DE   RecName: Full=Delta-like protein 1;
DE   AltName: Full=Drosophila Delta homolog 1;
DE            Short=Delta1;
DE            Short=H-Delta-1;
DE   Flags: Precursor;
GN   Name=DLL1; ORFNames=UNQ146/PRO172;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005112; F:Notch binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0007386; P:compartment pattern specification; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
DR   GO; GO:0072070; P:loop of Henle development; IEA:Ensembl.
DR   GO; GO:0045608; P:negative regulation of auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IMP:UniProt.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0072014; P:proximal tubule development; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.
DR   GO; GO:0001757; P:somite specification; IEA:Ensembl.
//
ID   DLL3_HUMAN              Reviewed;         618 AA.
AC   Q9NYJ7; E9PFG2; Q8NBS4;
DE   RecName: Full=Delta-like protein 3;
DE   AltName: Full=Drosophila Delta homolog 3;
DE            Short=Delta3;
DE   Flags: Precursor;
GN   Name=DLL3;
DR   GO; GO:0005112; F:Notch binding; NAS:UniProtKB.
DR   GO; GO:0007386; P:compartment pattern specification; IEA:Ensembl.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   DLL4_HUMAN              Reviewed;         685 AA.
AC   Q9NR61; Q3KP23; Q9NQT9;
DE   RecName: Full=Delta-like protein 4;
DE   AltName: Full=Drosophila Delta homolog 4;
DE            Short=Delta4;
DE   Flags: Precursor;
GN   Name=DLL4; ORFNames=UNQ1895/PRO4341;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005112; F:Notch binding; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0072554; P:blood vessel lumenization; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:BHF-UCL.
DR   GO; GO:0003209; P:cardiac atrium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:UniProtKB.
DR   GO; GO:0035912; P:dorsal aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; ISS:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:BHF-UCL.
DR   GO; GO:0003344; P:pericardium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0061074; P:regulation of neural retina development; ISS:UniProtKB.
DR   GO; GO:0050767; P:regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0060579; P:ventral spinal cord interneuron fate commitment; IMP:UniProtKB.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; ISS:BHF-UCL.
//
ID   DLP1_HUMAN              Reviewed;         399 AA.
AC   Q86YH6; Q33DR4; Q4G158; Q5VU38; Q5VU39; Q9NR58;
DE   RecName: Full=Decaprenyl-diphosphate synthase subunit 2;
DE            EC=2.5.1.91;
DE   AltName: Full=All-trans-decaprenyl-diphosphate synthase subunit 2;
DE   AltName: Full=Candidate tumor suppressor protein;
DE   AltName: Full=Decaprenyl pyrophosphate synthase subunit 2;
GN   Name=PDSS2; Synonyms=C6orf210, DLP1;
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:HGNC.
DR   GO; GO:0000010; F:trans-hexaprenyltranstransferase activity; IEA:Ensembl.
DR   GO; GO:0050347; F:trans-octaprenyltranstransferase activity; IEA:Ensembl.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IDA:HGNC.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0050878; P:regulation of body fluid levels; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IDA:HGNC.
//
ID   DLRB1_HUMAN             Reviewed;          96 AA.
AC   Q9NP97; B1AKR5; Q5TC72; Q96IV3; Q9NQM2;
DE   RecName: Full=Dynein light chain roadblock-type 1;
DE   AltName: Full=Bithoraxoid-like protein;
DE            Short=BLP;
DE   AltName: Full=Dynein light chain 2A, cytoplasmic;
DE   AltName: Full=Dynein-associated protein Km23;
DE   AltName: Full=Roadblock domain-containing protein 1;
GN   Name=DYNLRB1; Synonyms=BITH, DNCL2A, DNLC2A, ROBLD1; ORFNames=HSPC162;
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0007632; P:visual behavior; ISS:UniProtKB.
//
ID   DLRB2_HUMAN             Reviewed;          96 AA.
AC   Q8TF09;
DE   RecName: Full=Dynein light chain roadblock-type 2;
DE   AltName: Full=Dynein light chain 2B, cytoplasmic;
DE   AltName: Full=Roadblock domain-containing protein 2;
GN   Name=DYNLRB2; Synonyms=DNCL2B, DNLC2B, ROBLD2;
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DLX2_HUMAN              Reviewed;         328 AA.
AC   Q07687; B4DMK4; B7ZA14;
DE   RecName: Full=Homeobox protein DLX-2;
GN   Name=DLX2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0048755; P:branching morphogenesis of a nerve; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0021893; P:cerebral cortex GABAergic interneuron fate commitment; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0021882; P:regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0021544; P:subpallium development; IEA:Ensembl.
//
ID   DLX1_HUMAN              Reviewed;         255 AA.
AC   P56177; D3DPD7; Q53ZU4; Q7Z724; Q8IYB2;
DE   RecName: Full=Homeobox protein DLX-1;
GN   Name=DLX1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0021893; P:cerebral cortex GABAergic interneuron fate commitment; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0021882; P:regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0021544; P:subpallium development; IEA:Ensembl.
//
ID   DLX4_HUMAN              Reviewed;         240 AA.
AC   Q92988; D3DTX2; D3DTX3; O60480; Q13265; Q6PJK0; Q9HBE0;
DE   RecName: Full=Homeobox protein DLX-4;
DE   AltName: Full=Beta protein 1;
DE   AltName: Full=Homeobox protein DLX-7;
DE   AltName: Full=Homeobox protein DLX-8;
GN   Name=DLX4; Synonyms=BP1, DLX7, DLX8, DLX9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   DLX3_HUMAN              Reviewed;         287 AA.
AC   O60479; B3KQL6;
DE   RecName: Full=Homeobox protein DLX-3;
GN   Name=DLX3;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0071895; P:odontoblast differentiation; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
//
ID   DLX5_HUMAN              Reviewed;         289 AA.
AC   P56178; Q9UPL1;
DE   RecName: Full=Homeobox protein DLX-5;
GN   Name=DLX5;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; ISS:BHF-UCL.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0060166; P:olfactory pit development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:1901522; P:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   DLX6_HUMAN              Reviewed;         175 AA.
AC   P56179; A4D1I2; B3KSQ0; J3KR92; Q3ZAR6; Q9UPL2;
DE   RecName: Full=Homeobox protein DLX-6;
GN   Name=DLX6;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060322; P:head development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   DMAP1_HUMAN             Reviewed;         467 AA.
AC   Q9NPF5; A8K001; D3DPY8; Q0JSM4; Q5TG41; Q7Z3H7; Q9H0S8; Q9P2C2;
DE   RecName: Full=DNA methyltransferase 1-associated protein 1;
DE            Short=DNMAP1;
DE            Short=DNMT1-associated protein 1;
GN   Name=DMAP1; Synonyms=KIAA1425;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; TAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMA_HUMAN               Reviewed;         261 AA.
AC   P28067; Q29639; Q29640;
DE   RecName: Full=HLA class II histocompatibility antigen, DM alpha chain;
DE   AltName: Full=MHC class II antigen DMA;
DE   AltName: Full=Really interesting new gene 6 protein;
DE   Flags: Precursor;
GN   Name=HLA-DMA; Synonyms=DMA, RING6;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:Ensembl.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0050778; P:positive regulation of immune response; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
//
ID   DMBT1_HUMAN             Reviewed;        2413 AA.
AC   Q9UGM3; A6NDG4; A6NDJ5; A8E4R5; B1ARE7; B1ARE8; B1ARE9; B1ARF0;
AC   B7Z8Y2; F8WEF7; Q59EX0; Q5JR26; Q6MZN4; Q96DU4; Q9UGM2; Q9UJ57;
AC   Q9UKJ4; Q9Y211; Q9Y4V9;
DE   RecName: Full=Deleted in malignant brain tumors 1 protein;
DE   AltName: Full=Glycoprotein 340;
DE            Short=Gp-340;
DE   AltName: Full=Hensin;
DE   AltName: Full=Salivary agglutinin;
DE            Short=SAG;
DE   AltName: Full=Surfactant pulmonary-associated D-binding protein;
DE   Flags: Precursor;
GN   Name=DMBT1; Synonyms=GP340;
DR   GO; GO:0048306; F:calcium-dependent protein binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; NAS:UniProtKB.
DR   GO; GO:0008329; F:signaling pattern recognition receptor activity; TAS:UniProtKB.
DR   GO; GO:0035375; F:zymogen binding; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0030855; P:epithelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0043152; P:induction of bacterial agglutination; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; TAS:GOC.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:GOC.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DMBX1_HUMAN             Reviewed;         382 AA.
AC   Q8NFW5; A6NNN2; Q8NFW6; Q8NHD9;
DE   RecName: Full=Diencephalon/mesencephalon homeobox protein 1;
DE   AltName: Full=Orthodenticle homolog 3;
DE   AltName: Full=Paired-like homeobox protein DMBX1;
GN   Name=DMBX1; Synonyms=MBX, OTX3, PAXB;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0008343; P:adult feeding behavior; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0048589; P:developmental growth; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMB_HUMAN               Reviewed;         263 AA.
AC   P28068; O77936; Q13012; Q29751; Q58ZE2; Q5SNZ8; Q5STC4; Q9XRX2;
DE   RecName: Full=HLA class II histocompatibility antigen, DM beta chain;
DE   AltName: Full=MHC class II antigen DMB;
DE   AltName: Full=Really interesting new gene 7 protein;
DE   Flags: Precursor;
GN   Name=HLA-DMB; Synonyms=DMB, RING7;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   DMC1_HUMAN              Reviewed;         340 AA.
AC   Q14565; A8K9A2; Q08AI1; Q99498; Q9UH11;
DE   RecName: Full=Meiotic recombination protein DMC1/LIM15 homolog;
GN   Name=DMC1; Synonyms=DMC1H, LIM15;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   DMD_HUMAN               Reviewed;        3685 AA.
AC   P11532; E9PDN1; Q02295; Q14169; Q14170; Q5JYU0; Q6NSJ9; Q7KZ48;
AC   Q8N754; Q9UCW3; Q9UCW4;
DE   RecName: Full=Dystrophin;
GN   Name=DMD;
DR   GO; GO:0003779; F:actin binding; TAS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0002162; F:dystroglycan binding; IPI:UniProtKB.
DR   GO; GO:0017022; F:myosin binding; IDA:BHF-UCL.
DR   GO; GO:0050998; F:nitric-oxide synthase binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008307; F:structural constituent of muscle; IDA:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0086001; P:cardiac muscle cell action potential; ISS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0043623; P:cellular protein complex assembly; ISS:BHF-UCL.
DR   GO; GO:0034613; P:cellular protein localization; IMP:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0044458; P:motile cilium assembly; TAS:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; NAS:ProtInc.
DR   GO; GO:1902083; P:negative regulation of peptidyl-cysteine S-nitrosylation; ISS:BHF-UCL.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0043043; P:peptide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IMP:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:2000651; P:positive regulation of sodium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; ISS:BHF-UCL.
DR   GO; GO:0090287; P:regulation of cellular response to growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL.
DR   GO; GO:0014819; P:regulation of skeletal muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0014809; P:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; ISS:BHF-UCL.
DR   GO; GO:1901385; P:regulation of voltage-gated calcium channel activity; ISS:BHF-UCL.
//
ID   DMKN_HUMAN              Reviewed;         476 AA.
AC   Q6E0U4; A3EZ79; A3EZ80; A3EZ81; A3EZ82; A3EZ83; C9J4P6; C9J5N8;
AC   C9JAL3; Q32W58; Q32W62; Q32W63; Q32W64; Q32W65; Q32W66; Q32W67;
AC   Q6E0U5; Q6UXC7; Q96EW8; Q9BSY6;
DE   RecName: Full=Dermokine;
DE   AltName: Full=Epidermis-specific secreted protein SK30/SK89;
DE   Flags: Precursor;
GN   Name=DMKN; ORFNames=UNQ729/PRO1411;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   DMP1_HUMAN              Reviewed;         513 AA.
AC   Q13316; A1L4L3; O43265;
DE   RecName: Full=Dentin matrix acidic phosphoprotein 1;
DE            Short=DMP-1;
DE            Short=Dentin matrix protein 1;
DE   Flags: Precursor;
GN   Name=DMP1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   DMP34_HUMAN             Reviewed;         102 AA.
AC   Q6PK57;
DE   RecName: Full=Putative GED domain-containing protein DNM1P34;
DE   AltName: Full=DNM1 pseudogene 34;
GN   Name=DNM1P34;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
//
ID   DMP46_HUMAN             Reviewed;         220 AA.
AC   Q6ZS02; Q3ZCN3;
DE   RecName: Full=Putative GED domain-containing protein DNM1P46;
DE   AltName: Full=DNM1 pseudogene 46;
GN   Name=DNM1P46; Synonyms=C15orf51;
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
//
ID   DMP4_HUMAN              Reviewed;         584 AA.
AC   Q8IXL6; A4D2Q5; L8B5W8; Q5I0W9; Q7Z4I0; Q9NPT2;
DE   RecName: Full=Extracellular serine/threonine protein kinase FAM20C;
DE            EC=2.7.11.1;
DE   AltName: Full=Dentin matrix protein 4;
DE            Short=DMP-4;
DE   AltName: Full=Golgi-enriched fraction casein kinase;
DE            Short=GEF-CK;
DE   AltName: Full=Protein FAM20C;
DE   Flags: Precursor;
GN   Name=FAM20C; Synonyms=DMP4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProt.
DR   GO; GO:0097187; P:dentinogenesis; IEA:Ensembl.
DR   GO; GO:0070166; P:enamel mineralization; IEA:Ensembl.
DR   GO; GO:0071895; P:odontoblast differentiation; IEA:Ensembl.
DR   GO; GO:0036179; P:osteoclast maturation; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051174; P:regulation of phosphorus metabolic process; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   DMPK_HUMAN              Reviewed;         629 AA.
AC   Q09013; Q16205; Q6P5Z6;
DE   RecName: Full=Myotonin-protein kinase;
DE            Short=MT-PK;
DE            EC=2.7.11.1;
DE   AltName: Full=DM-kinase;
DE            Short=DMK;
DE   AltName: Full=DM1 protein kinase;
DE   AltName: Full=DMPK;
DE   AltName: Full=Myotonic dystrophy protein kinase;
GN   Name=DMPK; Synonyms=DM1PK, MDPK;
DR   GuidetoPHARMACOLOGY; 1505; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017020; F:myosin phosphatase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0010657; P:muscle cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0014853; P:regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IDA:UniProtKB.
DR   GO; GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.
DR   GO; GO:0014722; P:regulation of skeletal muscle contraction by calcium ion signaling; IEA:Ensembl.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0051823; P:regulation of synapse structural plasticity; IEA:Ensembl.
//
ID   DMRT1_HUMAN             Reviewed;         373 AA.
AC   Q9Y5R6; B2R913; Q6T1H8; Q6T1H9; Q8IW77;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor 1;
DE   AltName: Full=DM domain expressed in testis protein 1;
GN   Name=DMRT1; Synonyms=DMT1;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0002176; P:male germ cell proliferation; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0030238; P:male sex determination; ISS:UniProtKB.
DR   GO; GO:0046661; P:male sex differentiation; ISS:UniProtKB.
DR   GO; GO:0045835; P:negative regulation of meiosis; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:2000020; P:positive regulation of male gonad development; IEA:Ensembl.
DR   GO; GO:0060903; P:positive regulation of meiosis I; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007530; P:sex determination; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMRT2_HUMAN             Reviewed;         561 AA.
AC   Q9Y5R5; B1ANC0; B9EGJ1; Q9NPG6; Q9NQR6;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor 2;
DE   AltName: Full=Doublesex-like 2 protein;
DE            Short=DSXL-2;
GN   Name=DMRT2; Synonyms=DSXL2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:2000287; P:positive regulation of myotome development; IEA:Ensembl.
DR   GO; GO:0014807; P:regulation of somitogenesis; IEA:Ensembl.
DR   GO; GO:0007530; P:sex determination; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMRT3_HUMAN             Reviewed;         472 AA.
AC   Q9NQL9; Q7LA03; Q7LCH8; Q96SC7; Q9NRQ9;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor 3;
GN   Name=DMRT3; Synonyms=DMRTA3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0046661; P:male sex differentiation; IEA:Ensembl.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0007548; P:sex differentiation; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0021521; P:ventral spinal cord interneuron specification; IEA:Ensembl.
//
ID   DMRTA_HUMAN             Reviewed;         504 AA.
AC   Q5VZB9; A1L481; Q8N8Y9; Q9H4B9;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor A1;
GN   Name=DMRTA1; Synonyms=DMO;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0060179; P:male mating behavior; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMRTB_HUMAN             Reviewed;         342 AA.
AC   Q96MA1; Q96SD2;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor B1;
GN   Name=DMRTB1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMRTD_HUMAN             Reviewed;         367 AA.
AC   Q8IXT2; Q8N6Q2; Q96M39; Q96SD4;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor C2;
GN   Name=DMRTC2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:1900111; P:positive regulation of histone H3-K9 dimethylation; IEA:Ensembl.
DR   GO; GO:1900114; P:positive regulation of histone H3-K9 trimethylation; IEA:Ensembl.
DR   GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007290; P:spermatid nucleus elongation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMRTC_HUMAN             Reviewed;         192 AA.
AC   Q5HYR2; Q5HYR0; Q5U5K2; Q8N6L3; Q96SD3;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor C1;
GN   Name=DMRTC1;
GN   and
GN   Name=DMRTC1B;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMTA2_HUMAN             Reviewed;         542 AA.
AC   Q96SC8; Q5TFQ3;
DE   RecName: Full=Doublesex- and mab-3-related transcription factor A2;
DE   AltName: Full=Doublesex- and mab-3-related transcription factor 5;
GN   Name=DMRTA2; Synonyms=DMRT5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   DMTF1_HUMAN             Reviewed;         760 AA.
AC   Q9Y222; B2RBE1; B4DJS5; Q05C48; Q59G79; Q6IS13; Q969T2; Q9H2Z2;
AC   Q9H2Z3;
DE   RecName: Full=Cyclin-D-binding Myb-like transcription factor 1;
DE            Short=hDMTF1;
DE   AltName: Full=Cyclin-D-interacting Myb-like protein 1;
DE            Short=hDMP1;
GN   Name=DMTF1; Synonyms=DMP1;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DMWD_HUMAN              Reviewed;         674 AA.
AC   Q09019;
DE   RecName: Full=Dystrophia myotonica WD repeat-containing protein;
DE   AltName: Full=Dystrophia myotonica-containing WD repeat motif protein;
DE   AltName: Full=Protein 59;
DE   AltName: Full=Protein DMR-N9;
GN   Name=DMWD; Synonyms=DM9;
//
ID   DMXL1_HUMAN             Reviewed;        3027 AA.
AC   Q9Y485;
DE   RecName: Full=DmX-like protein 1;
DE            Short=X-like 1 protein;
GN   Name=DMXL1; Synonyms=XL1;
//
ID   DMXL2_HUMAN             Reviewed;        3036 AA.
AC   Q8TDJ6; B2RTR3; B7ZMH3; F5GWF1; O94938;
DE   RecName: Full=DmX-like protein 2;
DE   AltName: Full=Rabconnectin-3;
GN   Name=DMXL2; Synonyms=KIAA0856;
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:MGI.
//
ID   DNA2_HUMAN              Reviewed;        1060 AA.
AC   P51530; Q2NKM1; Q5TC49; Q5TC50; Q6P455; Q6PI80; Q7Z6H9; Q8N346;
DE   RecName: Full=DNA replication ATP-dependent helicase/nuclease DNA2;
DE            Short=hDNA2;
DE   AltName: Full=DNA replication ATP-dependent helicase-like homolog;
DE   Includes:
DE     RecName: Full=DNA replication nuclease DNA2;
DE              EC=3.1.-.-;
DE   Includes:
DE     RecName: Full=DNA replication ATP-dependent helicase DNA2;
DE              EC=3.6.4.12;
GN   Name=DNA2; Synonyms=DNA2L, KIAA0083;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; TAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043142; F:single-stranded DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0016890; F:site-specific endodeoxyribonuclease activity, specific for altered base; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0000729; P:DNA double-strand break processing; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0000076; P:DNA replication checkpoint; IMP:UniProtKB.
DR   GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IDA:UniProtKB.
DR   GO; GO:0043137; P:DNA replication, removal of RNA primer; IDA:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0043504; P:mitochondrial DNA repair; IDA:UniProtKB.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
//
ID   DNAI1_HUMAN             Reviewed;         699 AA.
AC   Q9UI46; Q5T8G7; Q8NHQ7; Q9UEZ8;
DE   RecName: Full=Dynein intermediate chain 1, axonemal;
DE   AltName: Full=Axonemal dynein intermediate chain 1;
GN   Name=DNAI1;
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
//
ID   DNAI2_HUMAN             Reviewed;         605 AA.
AC   Q9GZS0; C9J0S6; Q8IUW4; Q9H179; Q9NT53;
DE   RecName: Full=Dynein intermediate chain 2, axonemal;
DE   AltName: Full=Axonemal dynein intermediate chain 2;
GN   Name=DNAI2;
DR   GO; GO:0003777; F:microtubule motor activity; IMP:MGI.
DR   GO; GO:0042384; P:cilium assembly; IMP:MGI.
DR   GO; GO:0008152; P:metabolic process; IMP:GOC.
//
ID   DNAL1_HUMAN             Reviewed;         190 AA.
AC   Q4LDG9; B2RD38; Q5JPB7; Q9BS43;
DE   RecName: Full=Dynein light chain 1, axonemal;
GN   Name=DNAL1; Synonyms=C14orf168;
//
ID   DNAL4_HUMAN             Reviewed;         105 AA.
AC   O96015; Q6FGB2; Q6FGD0;
DE   RecName: Full=Dynein light chain 4, axonemal;
GN   Name=DNAL4;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
//
ID   DNAS1_HUMAN             Reviewed;         282 AA.
AC   P24855; Q14UU9; Q14UV0;
DE   RecName: Full=Deoxyribonuclease-1;
DE            EC=3.1.21.1;
DE   AltName: Full=Deoxyribonuclease I;
DE            Short=DNase I;
DE   AltName: INN=Dornase alfa;
DE   Flags: Precursor;
GN   Name=DNASE1; Synonyms=DNL1, DRNI;
DR   GO; GO:0004530; F:deoxyribonuclease I activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   DND1_HUMAN              Reviewed;         353 AA.
AC   Q8IYX4;
DE   RecName: Full=Dead end protein homolog 1;
DE   AltName: Full=RNA-binding motif, single-stranded-interacting protein 4;
GN   Name=DND1; Synonyms=RBMS4;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0060965; P:negative regulation of gene silencing by miRNA; IDA:UniProtKB.
//
ID   DNER_HUMAN              Reviewed;         737 AA.
AC   Q8NFT8; A6NP39; Q53R88; Q53TP7; Q53TQ5; Q8IYT0; Q8TB42; Q9NTF1;
AC   Q9UDM2;
DE   RecName: Full=Delta and Notch-like epidermal growth factor-related receptor;
DE   Flags: Precursor;
GN   Name=DNER; Synonyms=BET; ORFNames=UNQ262/PRO299;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0030276; F:clathrin binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IEP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; NAS:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; NAS:UniProtKB.
//
ID   DNHD1_HUMAN             Reviewed;        4753 AA.
AC   Q96M86; Q2NKK8; Q6UWI9; Q8NAA2; Q8TEE6; Q9NSZ9;
DE   RecName: Full=Dynein heavy chain domain-containing protein 1;
DE   AltName: Full=Dynein heavy chain domain 1-like protein;
DE   AltName: Full=Protein CCDC35;
GN   Name=DNHD1; Synonyms=C11orf47, CCDC35, DHCD1, DNHD1L;
GN   ORFNames=UNQ5781/PRO12970;
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DNJ5B_HUMAN             Reviewed;         199 AA.
AC   Q9UF47; Q969Y8;
DE   RecName: Full=DnaJ homolog subfamily C member 5B;
DE   AltName: Full=Cysteine string protein beta;
DE            Short=CSP-beta;
GN   Name=DNAJC5B;
//
ID   DNJ5G_HUMAN             Reviewed;         189 AA.
AC   Q8N7S2; Q53SY5; Q8IYQ4; Q96RJ8;
DE   RecName: Full=DnaJ homolog subfamily C member 5G;
DE   AltName: Full=Cysteine string protein-gamma;
DE            Short=CSP-gamma;
GN   Name=DNAJC5G;
//
ID   DNJA1_HUMAN             Reviewed;         397 AA.
AC   P31689; Q5T7Q0; Q86TL9;
DE   RecName: Full=DnaJ homolog subfamily A member 1;
DE   AltName: Full=DnaJ protein homolog 2;
DE   AltName: Full=HSDJ;
DE   AltName: Full=Heat shock 40 kDa protein 4;
DE   AltName: Full=Heat shock protein J2;
DE            Short=HSJ-2;
DE   AltName: Full=Human DnaJ protein 2;
DE            Short=hDj-2;
DE   Flags: Precursor;
GN   Name=DNAJA1; Synonyms=DNAJ2, HDJ2, HSJ2, HSPF4;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0009408; P:response to heat; IEA:InterPro.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   DNJA2_HUMAN             Reviewed;         412 AA.
AC   O60884; B2R7L7; O14711;
DE   RecName: Full=DnaJ homolog subfamily A member 2;
DE   AltName: Full=Cell cycle progression restoration gene 3 protein;
DE   AltName: Full=Dnj3;
DE            Short=Dj3;
DE   AltName: Full=HIRA-interacting protein 4;
DE   AltName: Full=Renal carcinoma antigen NY-REN-14;
DE   Flags: Precursor;
GN   Name=DNAJA2; Synonyms=CPR3, HIRIP4;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0009408; P:response to heat; IEA:InterPro.
//
ID   DNJA4_HUMAN             Reviewed;         397 AA.
AC   Q8WW22; E9PDM9; Q6AW87; Q8N5Z4; Q8N7P2;
DE   RecName: Full=DnaJ homolog subfamily A member 4;
DE   Flags: Precursor;
GN   Name=DNAJA4;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:UniProt.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0009408; P:response to heat; IEA:InterPro.
//
ID   DNJA3_HUMAN             Reviewed;         480 AA.
AC   Q96EY1; B2RAJ5; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96IV1; Q9NYH8;
DE   RecName: Full=DnaJ homolog subfamily A member 3, mitochondrial;
DE   AltName: Full=DnaJ protein Tid-1;
DE            Short=hTid-1;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 57;
DE   AltName: Full=Tumorous imaginal discs protein Tid56 homolog;
DE   Flags: Precursor;
GN   Name=DNAJA3; Synonyms=HCA57, TID1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005133; F:interferon-gamma receptor binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006924; P:activation-induced cell death of T cells; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0009408; P:response to heat; IEA:InterPro.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
//
ID   DNJB1_HUMAN             Reviewed;         340 AA.
AC   P25685;
DE   RecName: Full=DnaJ homolog subfamily B member 1;
DE   AltName: Full=DnaJ protein homolog 1;
DE   AltName: Full=Heat shock 40 kDa protein 1;
DE            Short=HSP40;
DE            Short=Heat shock protein 40;
DE   AltName: Full=Human DnaJ protein 1;
DE            Short=hDj-1;
GN   Name=DNAJB1; Synonyms=DNAJ1, HDJ1, HSPF1;
DR   GO; GO:0001671; F:ATPase activator activity; IDA:BHF-UCL.
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0070389; P:chaperone cofactor-dependent protein refolding; IDA:UniProtKB.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:Ensembl.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:UniProt.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:BHF-UCL.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   DNJB2_HUMAN             Reviewed;         324 AA.
AC   P25686; A8K9P6; Q8IUK1; Q8IUK2; Q96F52;
DE   RecName: Full=DnaJ homolog subfamily B member 2;
DE   AltName: Full=DnaJ protein homolog 1;
DE   AltName: Full=Heat shock 40 kDa protein 3;
DE   AltName: Full=Heat shock protein J1;
DE            Short=HSJ-1;
GN   Name=DNAJB2; Synonyms=HSJ1, HSPF3;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:BHF-UCL.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0070628; F:proteasome binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IGI:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IGI:UniProtKB.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:BHF-UCL.
DR   GO; GO:0090086; P:negative regulation of protein deubiquitination; IDA:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   DNJB3_HUMAN             Reviewed;         145 AA.
AC   Q8WWF6;
DE   RecName: Full=DnaJ homolog subfamily B member 3;
GN   Name=DNAJB3; Synonyms=HCG3;
//
ID   DNJB4_HUMAN             Reviewed;         337 AA.
AC   Q9UDY4; B2R824; Q13431;
DE   RecName: Full=DnaJ homolog subfamily B member 4;
DE   AltName: Full=Heat shock 40 kDa protein 1 homolog;
DE            Short=HSP40 homolog;
DE            Short=Heat shock protein 40 homolog;
DE   AltName: Full=Human liver DnaJ-like protein;
GN   Name=DNAJB4; Synonyms=DNAJW, HLJ1;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0009408; P:response to heat; TAS:ProtInc.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   DNJB5_HUMAN             Reviewed;         348 AA.
AC   O75953; B3KN14; B4DSA6; J3KQM9; J3KR08; Q5T656; Q8TDR7; Q96EM4;
DE   RecName: Full=DnaJ homolog subfamily B member 5;
DE   AltName: Full=Heat shock protein Hsp40-2;
DE   AltName: Full=Heat shock protein Hsp40-3;
DE   AltName: Full=Heat shock protein cognate 40;
DE            Short=Hsc40;
GN   Name=DNAJB5; Synonyms=HSC40;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006986; P:response to unfolded protein; IEP:UniProtKB.
//
ID   DNJB6_HUMAN             Reviewed;         326 AA.
AC   O75190; A4D232; A8K7D8; A8KAG0; B4DN73; E9PCZ2; O95806; Q53EN8;
AC   Q59EF2; Q6FIC8; Q75MA2; Q9UIK6;
DE   RecName: Full=DnaJ homolog subfamily B member 6;
DE   AltName: Full=HHDJ1;
DE   AltName: Full=Heat shock protein J2;
DE            Short=HSJ-2;
DE   AltName: Full=MRJ;
DE   AltName: Full=MSJ-1;
GN   Name=DNAJB6; Synonyms=HSJ2, MRJ, MSJ1;
DR   GO; GO:0001671; F:ATPase activator activity; IDA:UniProtKB.
DR   GO; GO:0051087; F:chaperone binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0031072; F:heat shock protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0060710; P:chorio-allantoic fusion; IEA:Ensembl.
DR   GO; GO:0060717; P:chorion development; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0045109; P:intermediate filament organization; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:UniProt.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:GOC.
DR   GO; GO:0006457; P:protein folding; IDA:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0060715; P:syncytiotrophoblast cell differentiation involved in labyrinthine layer development; IEA:Ensembl.
//
ID   DNJB7_HUMAN             Reviewed;         309 AA.
AC   Q7Z6W7; Q2M220; Q5H904; Q8WYJ7;
DE   RecName: Full=DnaJ homolog subfamily B member 7;
GN   Name=DNAJB7; Synonyms=HSC3;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
//
ID   DNJB8_HUMAN             Reviewed;         232 AA.
AC   Q8NHS0; B3KWV7;
DE   RecName: Full=DnaJ homolog subfamily B member 8;
GN   Name=DNAJB8;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0044183; F:protein binding involved in protein folding; IDA:MGI.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:MGI.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:UniProt.
//
ID   DNJB9_HUMAN             Reviewed;         223 AA.
AC   Q9UBS3;
DE   RecName: Full=DnaJ homolog subfamily B member 9;
DE   AltName: Full=Endoplasmic reticulum DNA J domain-containing protein 4;
DE            Short=ER-resident protein ERdj4;
DE            Short=ERdj4;
DE   AltName: Full=Microvascular endothelial differentiation gene 1 protein;
DE            Short=Mdg-1;
DE   Flags: Precursor;
GN   Name=DNAJB9; Synonyms=MDG1; ORFNames=UNQ743/PRO1471;
DR   GO; GO:0051787; F:misfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   DNJC1_HUMAN             Reviewed;         554 AA.
AC   Q96KC8; B0YIZ8; Q5VX89; Q9H6B8;
DE   RecName: Full=DnaJ homolog subfamily C member 1;
DE   AltName: Full=DnaJ protein homolog MTJ1;
DE   Flags: Precursor;
GN   Name=DNAJC1; Synonyms=HTJ1;
DR   GO; GO:0001671; F:ATPase activator activity; TAS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; TAS:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; TAS:GOC.
DR   GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR   GO; GO:0050708; P:regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
//
ID   DNJC2_HUMAN             Reviewed;         621 AA.
AC   Q99543; A4VCI0; Q9BVX1;
DE   RecName: Full=DnaJ homolog subfamily C member 2;
DE   AltName: Full=M-phase phosphoprotein 11;
DE   AltName: Full=Zuotin-related factor 1;
DE   Contains:
DE     RecName: Full=DnaJ homolog subfamily C member 2, N-terminally processed;
GN   Name=DNAJC2; Synonyms=MPHOSPH11, MPP11, ZRF1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0051083; P:'de novo' cotranslational protein folding; TAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DNJC3_HUMAN             Reviewed;         504 AA.
AC   Q13217; Q86WT9; Q8N4N2;
DE   RecName: Full=DnaJ homolog subfamily C member 3;
DE   AltName: Full=Endoplasmic reticulum DNA J domain-containing protein 6;
DE            Short=ER-resident protein ERdj6;
DE            Short=ERdj6;
DE   AltName: Full=Interferon-induced, double-stranded RNA-activated protein kinase inhibitor;
DE   AltName: Full=Protein kinase inhibitor of 58 kDa;
DE            Short=Protein kinase inhibitor p58;
DE   Flags: Precursor;
GN   Name=DNAJC3; Synonyms=P58IPK, PRKRI;
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:Ensembl.
//
ID   DNJC4_HUMAN             Reviewed;         241 AA.
AC   Q9NNZ3; O14716;
DE   RecName: Full=DnaJ homolog subfamily C member 4;
DE   AltName: Full=DnaJ-like protein HSPF2;
DE   AltName: Full=Multiple endocrine neoplasia type 1 candidate protein number 18;
GN   Name=DNAJC4; Synonyms=HSPF2, MCG18;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   DNJC5_HUMAN             Reviewed;         198 AA.
AC   Q9H3Z4; A8K0M0; B3KY68; E1P5G8; Q9H3Z5; Q9H7H2;
DE   RecName: Full=DnaJ homolog subfamily C member 5;
DE   AltName: Full=Cysteine string protein;
DE            Short=CSP;
GN   Name=DNAJC5; Synonyms=CSP;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   DNJC7_HUMAN             Reviewed;         494 AA.
AC   Q99615; Q7Z784;
DE   RecName: Full=DnaJ homolog subfamily C member 7;
DE   AltName: Full=Tetratricopeptide repeat protein 2;
DE            Short=TPR repeat protein 2;
GN   Name=DNAJC7; Synonyms=TPR2, TTC2;
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070389; P:chaperone cofactor-dependent protein refolding; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
//
ID   DNJC8_HUMAN             Reviewed;         253 AA.
AC   O75937; B4DUU4; D3DPM0; Q6IBA4; Q8N4Z5; Q9P051; Q9P067;
DE   RecName: Full=DnaJ homolog subfamily C member 8;
DE   AltName: Full=Splicing protein spf31;
GN   Name=DNAJC8; Synonyms=SPF31; ORFNames=HSPC315, HSPC331;
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   DNJC9_HUMAN             Reviewed;         260 AA.
AC   Q8WXX5; B2RMW6;
DE   RecName: Full=DnaJ homolog subfamily C member 9;
DE   AltName: Full=DnaJ protein SB73;
GN   Name=DNAJC9;
DR   GO; GO:0035176; P:social behavior; IEP:UniProtKB.
//
ID   DNLI1_HUMAN             Reviewed;         919 AA.
AC   P18858; B2RAI8; Q32P23;
DE   RecName: Full=DNA ligase 1;
DE            EC=6.5.1.1;
DE   AltName: Full=DNA ligase I;
DE   AltName: Full=Polydeoxyribonucleotide synthase [ATP] 1;
GN   Name=LIG1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IBA:RefGenome.
DR   GO; GO:0003909; F:DNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:Ensembl.
DR   GO; GO:0006273; P:lagging strand elongation; IBA:RefGenome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DNLI3_HUMAN             Reviewed;        1009 AA.
AC   P49916; Q16714; Q6NVK3;
DE   RecName: Full=DNA ligase 3;
DE            EC=6.5.1.1;
DE   AltName: Full=DNA ligase III;
DE   AltName: Full=Polydeoxyribonucleotide synthase [ATP] 3;
GN   Name=LIG3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IBA:RefGenome.
DR   GO; GO:0003909; F:DNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006288; P:base-excision repair, DNA ligation; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:Ensembl.
DR   GO; GO:0006273; P:lagging strand elongation; IBA:RefGenome.
DR   GO; GO:0043504; P:mitochondrial DNA repair; IEA:Ensembl.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; IBA:RefGenome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   DNLI4_HUMAN             Reviewed;         911 AA.
AC   P49917; Q8IY66; Q8TEU5;
DE   RecName: Full=DNA ligase 4;
DE            EC=6.5.1.1;
DE   AltName: Full=DNA ligase IV;
DE   AltName: Full=Polydeoxyribonucleotide synthase [ATP] 4;
GN   Name=LIG4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IDA:UniProtKB.
DR   GO; GO:0003909; F:DNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; ISS:UniProtKB.
DR   GO; GO:0006266; P:DNA ligation; IDA:UniProtKB.
DR   GO; GO:0051102; P:DNA ligation involved in DNA recombination; ISS:UniProtKB.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IDA:UniProtKB.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0033152; P:immunoglobulin V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0006273; P:lagging strand elongation; IBA:RefGenome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0002328; P:pro-B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; ISS:UniProtKB.
DR   GO; GO:0010165; P:response to X-ray; IMP:UniProtKB.
DR   GO; GO:0000012; P:single strand break repair; IDA:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0033153; P:T cell receptor V(D)J recombination; ISS:UniProtKB.
DR   GO; GO:0033151; P:V(D)J recombination; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   DNLZ_HUMAN              Reviewed;         178 AA.
AC   Q5SXM8; B2RUX5; B9EJE1;
DE   RecName: Full=DNL-type zinc finger protein;
DE   AltName: Full=Hsp70-escort protein 1;
DE            Short=HEP1;
DE   AltName: Full=mtHsp70-escort protein;
DE   Flags: Precursor;
GN   Name=DNLZ; Synonyms=C9orf151;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   DNM1L_HUMAN             Reviewed;         736 AA.
AC   O00429; A8K4X9; B4DGC9; B4DSU8; J3KPI2; O14541; O60709; Q59GN9;
AC   Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2;
DE   RecName: Full=Dynamin-1-like protein;
DE            EC=3.6.5.5;
DE   AltName: Full=Dnm1p/Vps1p-like protein;
DE            Short=DVLP;
DE   AltName: Full=Dynamin family member proline-rich carboxyl-terminal domain less;
DE            Short=Dymple;
DE   AltName: Full=Dynamin-like protein;
DE   AltName: Full=Dynamin-like protein 4;
DE   AltName: Full=Dynamin-like protein IV;
DE            Short=HdynIV;
DE   AltName: Full=Dynamin-related protein 1;
GN   Name=DNM1L; Synonyms=DLP1, DRP1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0003374; P:dynamin polymerization involved in mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0090149; P:membrane fission involved in mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; IDA:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:MGI.
DR   GO; GO:0070266; P:necroptotic process; IMP:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; TAS:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0010821; P:regulation of mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:1900063; P:regulation of peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0032459; P:regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IMP:UniProtKB.
//
ID   DNM3A_HUMAN             Reviewed;         912 AA.
AC   Q9Y6K1; E9PEB8; Q86TE8; Q86XF5; Q8IZV0; Q8WXU9;
DE   RecName: Full=DNA (cytosine-5)-methyltransferase 3A;
DE            Short=Dnmt3a;
DE            EC=2.1.1.37;
DE   AltName: Full=DNA methyltransferase HsaIIIA;
DE            Short=DNA MTase HsaIIIA;
DE            Short=M.HsaIIIA;
GN   Name=DNMT3A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0051718; F:DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045322; F:unmethylated CpG binding; IEA:Ensembl.
DR   GO; GO:0090116; P:C-5 methylation of cytosine; IDA:GOC.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0006306; P:DNA methylation; IDA:UniProtKB.
DR   GO; GO:0043045; P:DNA methylation involved in embryo development; IEA:Ensembl.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; IEA:Ensembl.
DR   GO; GO:0010424; P:DNA methylation on cytosine within a CG sequence; IEA:Ensembl.
DR   GO; GO:0044027; P:hypermethylation of CpG island; IEA:Ensembl.
DR   GO; GO:0006346; P:methylation-dependent chromatin silencing; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; TAS:UniProtKB.
DR   GO; GO:0046498; P:S-adenosylhomocysteine metabolic process; IEA:Ensembl.
DR   GO; GO:0046499; P:S-adenosylmethioninamine metabolic process; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   DNM3B_HUMAN             Reviewed;         853 AA.
AC   Q9UBC3; A2A2E2; B4DSM8; B4DSU1; E1P5M6; E1P5M7; E7EN63; E9PBF2;
AC   Q9UBD4; Q9UJQ5; Q9UKA6; Q9UNE5; Q9Y5R9; Q9Y5S0;
DE   RecName: Full=DNA (cytosine-5)-methyltransferase 3B;
DE            Short=Dnmt3b;
DE            EC=2.1.1.37;
DE   AltName: Full=DNA methyltransferase HsaIIIB;
DE            Short=DNA MTase HsaIIIB;
DE            Short=M.HsaIIIB;
GN   Name=DNMT3B;
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0051718; F:DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; IEA:Ensembl.
DR   GO; GO:0009008; F:DNA-methyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0045322; F:unmethylated CpG binding; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0006306; P:DNA methylation; NAS:UniProtKB.
DR   GO; GO:0010424; P:DNA methylation on cytosine within a CG sequence; IEA:Ensembl.
DR   GO; GO:0006346; P:methylation-dependent chromatin silencing; IEA:Ensembl.
DR   GO; GO:0051573; P:negative regulation of histone H3-K9 methylation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0031503; P:protein complex localization; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0046498; P:S-adenosylhomocysteine metabolic process; IEA:Ensembl.
DR   GO; GO:0046499; P:S-adenosylmethioninamine metabolic process; IEA:Ensembl.
//
ID   DNM3L_HUMAN             Reviewed;         386 AA.
AC   Q9UJW3; E9PB42; Q9BUJ4;
DE   RecName: Full=DNA (cytosine-5)-methyltransferase 3-like;
GN   Name=DNMT3L;
DR   GO; GO:0008047; F:enzyme activator activity; IDA:MGI.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060718; P:chorionic trophoblast cell differentiation; IEA:Ensembl.
DR   GO; GO:0006306; P:DNA methylation; NAS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   DNMBP_HUMAN             Reviewed;        1577 AA.
AC   Q6XZF7; Q8IVY3; Q9Y2L3;
DE   RecName: Full=Dynamin-binding protein;
DE   AltName: Full=Scaffold protein Tuba;
GN   Name=DNMBP; Synonyms=KIAA1010;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   DNMT1_HUMAN             Reviewed;        1616 AA.
AC   P26358; A0AV63; B7ZLW6; Q9UHG5; Q9ULA2; Q9UMZ6;
DE   RecName: Full=DNA (cytosine-5)-methyltransferase 1;
DE            Short=Dnmt1;
DE            EC=2.1.1.37;
DE   AltName: Full=CXXC-type zinc finger protein 9;
DE   AltName: Full=DNA methyltransferase HsaI;
DE            Short=DNA MTase HsaI;
DE            Short=M.HsaI;
DE   AltName: Full=MCMT;
GN   Name=DNMT1; Synonyms=AIM, CXXC9, DNMT;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0009008; F:DNA-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008327; F:methyl-CpG binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006306; P:DNA methylation; TAS:ProtInc.
DR   GO; GO:0016458; P:gene silencing; IEA:Ensembl.
DR   GO; GO:0010216; P:maintenance of DNA methylation; IDA:UniProtKB.
DR   GO; GO:0051573; P:negative regulation of histone H3-K9 methylation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DNPEP_HUMAN             Reviewed;         475 AA.
AC   Q9ULA0; Q9BW44; Q9NUV5;
DE   RecName: Full=Aspartyl aminopeptidase;
DE            EC=3.4.11.21;
GN   Name=DNPEP; Synonyms=ASPEP, DAP;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006518; P:peptide metabolic process; TAS:ProtInc.
//
ID   DNPH1_HUMAN             Reviewed;         174 AA.
AC   O43598; B2LUJ9;
DE   RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1;
DE            EC=3.2.2.-;
DE   AltName: Full=c-Myc-responsive protein RCL;
GN   Name=DNPH1; Synonyms=C6orf108, RCL;
DR   GO; GO:0070694; F:deoxyribonucleoside 5'-monophosphate N-glycosidase activity; ISS:UniProtKB.
DR   GO; GO:0050144; F:nucleoside deoxyribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0009159; P:deoxyribonucleoside monophosphate catabolic process; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.
//
ID   DNS2A_HUMAN             Reviewed;         360 AA.
AC   O00115; B2RD06; O43910;
DE   RecName: Full=Deoxyribonuclease-2-alpha;
DE            EC=3.1.22.1;
DE   AltName: Full=Acid DNase;
DE   AltName: Full=Deoxyribonuclease II alpha;
DE            Short=DNase II alpha;
DE   AltName: Full=Lysosomal DNase II;
DE   AltName: Full=R31240_2;
DE   Flags: Precursor;
GN   Name=DNASE2; Synonyms=DNASE2A, DNL2;
DR   GO; GO:0004531; F:deoxyribonuclease II activity; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IBA:RefGenome.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
//
ID   DNS2B_HUMAN             Reviewed;         361 AA.
AC   Q8WZ79; Q5VXD0; Q5VXD1; Q8WZ80; Q9NQW3;
DE   RecName: Full=Deoxyribonuclease-2-beta;
DE            EC=3.1.22.1;
DE   AltName: Full=DNase II-like acid DNase;
DE   AltName: Full=DNase2-like acid DNase;
DE   AltName: Full=Deoxyribonuclease II beta;
DE            Short=DNase II beta;
DE   AltName: Full=Endonuclease DLAD;
DE   Flags: Precursor;
GN   Name=DNASE2B; Synonyms=DLAD;
DR   GO; GO:0004531; F:deoxyribonuclease II activity; IBA:RefGenome.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IBA:RefGenome.
//
ID   DNSL1_HUMAN             Reviewed;         302 AA.
AC   P49184; D3DWW7; Q5HY41;
DE   RecName: Full=Deoxyribonuclease-1-like 1;
DE            EC=3.1.21.-;
DE   AltName: Full=DNase X;
DE   AltName: Full=Deoxyribonuclease I-like 1;
DE            Short=DNase I-like 1;
DE   AltName: Full=Muscle-specific DNase I-like;
DE   AltName: Full=XIB;
DE   Flags: Precursor;
GN   Name=DNASE1L1; Synonyms=DNAS1L1, DNL1L;
DR   GO; GO:0004536; F:deoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
//
ID   DNSL2_HUMAN             Reviewed;         299 AA.
AC   Q92874; E9PBY4; Q6JVM2; Q6JVM3;
DE   RecName: Full=Deoxyribonuclease-1-like 2;
DE            EC=3.1.21.-;
DE   AltName: Full=DNase I homolog protein DHP1;
DE   AltName: Full=Deoxyribonuclease I-like 2;
DE            Short=DNase I-like 2;
DE   Flags: Precursor;
GN   Name=DNASE1L2; Synonyms=DHP1, DNAS1L2;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004536; F:deoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
//
ID   DNSL3_HUMAN             Reviewed;         305 AA.
AC   Q13609; B2R8B1; B7Z707; O75803;
DE   RecName: Full=Deoxyribonuclease gamma;
DE            Short=DNase gamma;
DE            EC=3.1.21.-;
DE   AltName: Full=DNase I homolog protein DHP2;
DE   AltName: Full=Deoxyribonuclease I-like 3;
DE            Short=DNase I-like 3;
DE   AltName: Full=Liver and spleen DNase;
DE            Short=LS-DNase;
DE            Short=LSD;
DE   Flags: Precursor;
GN   Name=DNASE1L3; Synonyms=DHP2, DNAS1L3;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004536; F:deoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Ensembl.
DR   GO; GO:0010623; P:developmental programmed cell death; IEA:Ensembl.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
//
ID   DOA_HUMAN               Reviewed;         250 AA.
AC   P06340; Q58HU0; Q58HU1; Q5STC7; Q9TQC6; Q9TQC7; Q9TQC8; Q9TQC9;
AC   Q9TQD0; Q9TQD1; Q9TQD2; Q9TQD3;
DE   RecName: Full=HLA class II histocompatibility antigen, DO alpha chain;
DE   AltName: Full=MHC DN-alpha;
DE   AltName: Full=MHC DZ alpha;
DE   AltName: Full=MHC class II antigen DOA;
DE   Flags: Precursor;
GN   Name=HLA-DOA; Synonyms=HLA-DNA, HLA-DZA;
DR   GO; GO:0032395; F:MHC class II receptor activity; TAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0045580; P:regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   DOB_HUMAN               Reviewed;         273 AA.
AC   P13765; B0V0Y0; Q29746; Q29825; Q6FHC2;
DE   RecName: Full=HLA class II histocompatibility antigen, DO beta chain;
DE   AltName: Full=MHC class II antigen DOB;
DE   Flags: Precursor;
GN   Name=HLA-DOB;
DR   GO; GO:0032395; F:MHC class II receptor activity; TAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   DOC10_HUMAN             Reviewed;        2186 AA.
AC   Q96BY6; B3FL70; O75178; Q9NW06; Q9NXI8;
DE   RecName: Full=Dedicator of cytokinesis protein 10;
DE   AltName: Full=Zizimin-3;
GN   Name=DOCK10; Synonyms=KIAA0694, ZIZ3;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:UniProt.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOC11_HUMAN             Reviewed;        2073 AA.
AC   Q5JSL3; A6NMF0; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3;
DE   RecName: Full=Dedicator of cytokinesis protein 11;
DE   AltName: Full=Activated Cdc42-associated guanine nucleotide exchange factor;
DE            Short=ACG;
DE   AltName: Full=Zizimin-2;
GN   Name=DOCK11; Synonyms=ZIZ2;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOC2A_HUMAN             Reviewed;         400 AA.
AC   Q14183; Q6P4G4; Q7Z5G0; Q8IVX0;
DE   RecName: Full=Double C2-like domain-containing protein alpha;
DE            Short=Doc2;
DE            Short=Doc2-alpha;
GN   Name=DOC2A;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
//
ID   DOC2B_HUMAN             Reviewed;         412 AA.
AC   Q14184;
DE   RecName: Full=Double C2-like domain-containing protein beta;
DE            Short=Doc2-beta;
GN   Name=DOC2B; Synonyms=DOC2BL;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; ISS:UniProtKB.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; ISS:UniProtKB.
//
ID   DOCK1_HUMAN             Reviewed;        1865 AA.
AC   Q14185; A9Z1Z5;
DE   RecName: Full=Dedicator of cytokinesis protein 1;
DE   AltName: Full=180 kDa protein downstream of CRK;
DE            Short=DOCK180;
GN   Name=DOCK1;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.
DR   GO; GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   DOCK2_HUMAN             Reviewed;        1830 AA.
AC   Q92608; Q2M3I0; Q96AK7;
DE   RecName: Full=Dedicator of cytokinesis protein 2;
GN   Name=DOCK2; Synonyms=KIAA0209;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0042608; F:T cell receptor binding; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0046633; P:alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; IEA:Ensembl.
DR   GO; GO:0001768; P:establishment of T cell polarity; IEA:Ensembl.
DR   GO; GO:0001771; P:immunological synapse formation; IEA:Ensembl.
DR   GO; GO:0044351; P:macropinocytosis; ISS:UniProtKB.
DR   GO; GO:0001766; P:membrane raft polarization; IEA:Ensembl.
DR   GO; GO:0002277; P:myeloid dendritic cell activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB.
DR   GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   DOCK3_HUMAN             Reviewed;        2030 AA.
AC   Q8IZD9; O15017;
DE   RecName: Full=Dedicator of cytokinesis protein 3;
DE   AltName: Full=Modifier of cell adhesion;
DE   AltName: Full=Presenilin-binding protein;
DE            Short=PBP;
GN   Name=DOCK3; Synonyms=KIAA0299, MOCA;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOCK4_HUMAN             Reviewed;        1966 AA.
AC   Q8N1I0; O14584; O94824; Q8NB45;
DE   RecName: Full=Dedicator of cytokinesis protein 4;
GN   Name=DOCK4; Synonyms=KIAA0716;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:HGNC.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOCK5_HUMAN             Reviewed;        1870 AA.
AC   Q9H7D0; B2RNY0; Q5XKD5; Q6AI11; Q6PJS6; Q6ZTS6;
DE   RecName: Full=Dedicator of cytokinesis protein 5;
GN   Name=DOCK5;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; ISS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOCK6_HUMAN             Reviewed;        2047 AA.
AC   Q96HP0; A6H8X5; Q7Z7P4; Q9P2F2;
DE   RecName: Full=Dedicator of cytokinesis protein 6;
GN   Name=DOCK6; Synonyms=KIAA1395;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOCK7_HUMAN             Reviewed;        2140 AA.
AC   Q96N67; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32;
AC   Q8TB82; Q96NG6; Q96NI0; Q9C092;
DE   RecName: Full=Dedicator of cytokinesis protein 7;
GN   Name=DOCK7; Synonyms=KIAA1771;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0007409; P:axonogenesis; IMP:BHF-UCL.
DR   GO; GO:0045200; P:establishment of neuroblast polarity; IMP:BHF-UCL.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:BHF-UCL.
DR   GO; GO:0031175; P:neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOCK8_HUMAN             Reviewed;        2099 AA.
AC   Q8NF50; A2A350; A2BDF2; A4FU78; B7ZLP0; E9PH09; Q3MV16; Q5JPJ1;
AC   Q8TEP1; Q8WUY2; Q9BYJ5; Q9H1Q2; Q9H1Q3; Q9H308; Q9H7P2;
DE   RecName: Full=Dedicator of cytokinesis protein 8;
GN   Name=DOCK8;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOCK9_HUMAN             Reviewed;        2069 AA.
AC   Q9BZ29; B3KX25; E9PFM9; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25;
AC   Q9BZ26; Q9BZ27; Q9BZ28; Q9UPU4;
DE   RecName: Full=Dedicator of cytokinesis protein 9;
DE   AltName: Full=Cdc42 guanine nucleotide exchange factor zizimin-1;
GN   Name=DOCK9; Synonyms=KIAA1058;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   DOHH_HUMAN              Reviewed;         302 AA.
AC   Q9BU89; O75265;
DE   RecName: Full=Deoxyhypusine hydroxylase;
DE            Short=hDOHH;
DE            EC=1.14.99.29;
DE   AltName: Full=Deoxyhypusine dioxygenase;
DE   AltName: Full=Deoxyhypusine monooxygenase;
DE   AltName: Full=HEAT-like repeat-containing protein 1;
GN   Name=DOHH; Synonyms=HLRC1;
DR   GO; GO:0019135; F:deoxyhypusine monooxygenase activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   DOK1_HUMAN              Reviewed;         481 AA.
AC   Q99704; O43204; Q53TY2; Q9UHG6;
DE   RecName: Full=Docking protein 1;
DE   AltName: Full=Downstream of tyrosine kinase 1;
DE   AltName: Full=p62(dok);
DE   AltName: Full=pp62;
GN   Name=DOK1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   DOK2_HUMAN              Reviewed;         412 AA.
AC   O60496; Q8N5A4;
DE   RecName: Full=Docking protein 2;
DE   AltName: Full=Downstream of tyrosine kinase 2;
DE   AltName: Full=p56(dok-2);
GN   Name=DOK2;
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   DOK3_HUMAN              Reviewed;         496 AA.
AC   Q7L591; E9PAT0; H7BXS0; Q8N864; Q9BQB3; Q9H666;
DE   RecName: Full=Docking protein 3;
DE   AltName: Full=Downstream of tyrosine kinase 3;
GN   Name=DOK3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
//
ID   DOK4_HUMAN              Reviewed;         326 AA.
AC   Q8TEW6; O75209; Q9BTP2; Q9NVV3;
DE   RecName: Full=Docking protein 4;
DE   AltName: Full=Downstream of tyrosine kinase 4;
DE   AltName: Full=Insulin receptor substrate 5;
DE            Short=IRS-5;
DE            Short=IRS5;
GN   Name=DOK4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   DOK5_HUMAN              Reviewed;         306 AA.
AC   Q9P104; Q5T7Y0; Q5TE53; Q8TEW7; Q96H13; Q9BZ24; Q9NQF4; Q9Y411;
DE   RecName: Full=Docking protein 5;
DE   AltName: Full=Downstream of tyrosine kinase 5;
DE   AltName: Full=Insulin receptor substrate 6;
DE            Short=IRS-6;
DE            Short=IRS6;
GN   Name=DOK5; Synonyms=C20orf180;
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   DOK6_HUMAN              Reviewed;         331 AA.
AC   Q6PKX4; A6NNG3; Q4V9S3; Q8WUZ8; Q96HI2; Q96LU2;
DE   RecName: Full=Docking protein 6;
DE   AltName: Full=Downstream of tyrosine kinase 6;
GN   Name=DOK6; Synonyms=DOK5L;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   DOK7_HUMAN              Reviewed;         504 AA.
AC   Q18PE1; A2A499; A2RRD4; E9PB56; Q6P6A6; Q86XG5; Q8N2J3; Q8NBC1;
DE   RecName: Full=Protein Dok-7;
DE   AltName: Full=Downstream of tyrosine kinase 7;
GN   Name=DOK7; Synonyms=C4orf25;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
//
ID   DOLK_HUMAN              Reviewed;         538 AA.
AC   Q9UPQ8; Q5SRE6;
DE   RecName: Full=Dolichol kinase;
DE            EC=2.7.1.108;
DE   AltName: Full=Transmembrane protein 15;
GN   Name=DOLK; Synonyms=KIAA1094, TMEM15; ORFNames=UNQ2422/PRO4980;
DR   GO; GO:0004168; F:dolichol kinase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006489; P:dolichyl diphosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0043048; P:dolichyl monophosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   DONS_HUMAN              Reviewed;         566 AA.
AC   Q9NYP3; Q8NC53; Q9NSR9; Q9NVZ5; Q9NYP1; Q9NYP2;
DE   RecName: Full=Protein downstream neighbor of Son;
DE   AltName: Full=B17;
GN   Name=DONSON; Synonyms=C21orf60;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   DOP1_HUMAN              Reviewed;        2465 AA.
AC   Q5JWR5; Q86XV1; Q9H5J5; Q9NSL4; Q9UPN5; Q9Y414;
DE   RecName: Full=Protein dopey-1;
GN   Name=DOPEY1; Synonyms=KIAA1117;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DOP2_HUMAN              Reviewed;        2298 AA.
AC   Q9Y3R5; D3DSG5; Q6PJQ7; Q9UEZ3;
DE   RecName: Full=Protein dopey-2;
GN   Name=DOPEY2; Synonyms=C21orf5, KIAA0933;
DR   GO; GO:0007029; P:endoplasmic reticulum organization; ISS:HGNC.
DR   GO; GO:0006895; P:Golgi to endosome transport; ISS:HGNC.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DOPD_HUMAN              Reviewed;         118 AA.
AC   P30046; O00774; O60787; Q13534;
DE   RecName: Full=D-dopachrome decarboxylase;
DE            EC=4.1.1.84;
DE   AltName: Full=D-dopachrome tautomerase;
DE   AltName: Full=Phenylpyruvate tautomerase II;
GN   Name=DDT;
DR   GO; GO:0033981; F:D-dopachrome decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004167; F:dopachrome isomerase activity; TAS:ProtInc.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
//
ID   DOPO_HUMAN              Reviewed;         617 AA.
AC   P09172; Q5T381; Q96AG2;
DE   RecName: Full=Dopamine beta-hydroxylase;
DE            EC=1.14.17.1;
DE   AltName: Full=Dopamine beta-monooxygenase;
DE   Contains:
DE     RecName: Full=Soluble dopamine beta-hydroxylase;
GN   Name=DBH;
DR   GuidetoPHARMACOLOGY; 2486; -.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004500; F:dopamine beta-monooxygenase activity; TAS:Reactome.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0048149; P:behavioral response to ethanol; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0042423; P:catecholamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0042420; P:dopamine catabolic process; IEA:Ensembl.
DR   GO; GO:0042596; P:fear response; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0042309; P:homoiothermy; IEA:Ensembl.
DR   GO; GO:0002443; P:leukocyte mediated immunity; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0042421; P:norepinephrine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2001236; P:regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   DOPP1_HUMAN             Reviewed;         238 AA.
AC   Q86YN1; A8K3U8; B0QZG4; Q96GF8; Q9Y3G1;
DE   RecName: Full=Dolichyldiphosphatase 1;
DE            EC=3.6.1.43;
DE   AltName: Full=Dolichyl pyrophosphate phosphatase 1;
GN   Name=DOLPP1; Synonyms=LSFR2;
DR   GO; GO:0047874; F:dolichyldiphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006489; P:dolichyl diphosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0008610; P:lipid biosynthetic process; IBA:RefGenome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; ISS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   DOS_HUMAN               Reviewed;         725 AA.
AC   Q8N350; O43385;
DE   RecName: Full=Protein Dos;
GN   Name=DOS; Synonyms=C19orf26;
//
ID   DOT1L_HUMAN             Reviewed;        1739 AA.
AC   Q8TEK3; O60379; Q96JL1;
DE   RecName: Full=Histone-lysine N-methyltransferase, H3 lysine-79 specific;
DE            EC=2.1.1.43;
DE   AltName: Full=DOT1-like protein;
DE   AltName: Full=Histone H3-K79 methyltransferase;
DE            Short=H3-K79-HMTase;
DE   AltName: Full=Lysine N-methyltransferase 4;
GN   Name=DOT1L; Synonyms=KIAA1814, KMT4;
DR   GuidetoPHARMACOLOGY; 2650; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0034968; P:histone lysine methylation; IDA:GOC.
DR   GO; GO:0046425; P:regulation of JAK-STAT cascade; IDA:UniProtKB.
DR   GO; GO:2000677; P:regulation of transcription regulatory region DNA binding; IMP:UniProtKB.
//
ID   DOXA1_HUMAN             Reviewed;         343 AA.
AC   Q1HG43; Q8N6K9; Q96MI4;
DE   RecName: Full=Dual oxidase maturation factor 1;
DE   AltName: Full=Dual oxidase activator 1;
DE   AltName: Full=Numb-interacting protein;
GN   Name=DUOXA1; Synonyms=NIP, NUMBIP;
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DOXA2_HUMAN             Reviewed;         320 AA.
AC   Q1HG44; B2RPI9; H0YNQ6;
DE   RecName: Full=Dual oxidase maturation factor 2;
DE   AltName: Full=Dual oxidase activator 2;
GN   Name=DUOXA2;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   DP13A_HUMAN             Reviewed;         709 AA.
AC   Q9UKG1; Q9P2B9;
DE   RecName: Full=DCC-interacting protein 13-alpha;
DE            Short=Dip13-alpha;
DE   AltName: Full=Adapter protein containing PH domain, PTB domain and leucine zipper motif 1;
GN   Name=APPL1; Synonyms=APPL, DIP13A, KIAA1428;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043422; F:protein kinase B binding; IPI:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0090003; P:regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0046324; P:regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   DP13B_HUMAN             Reviewed;         664 AA.
AC   Q8NEU8; B7Z411; B7Z4B0; F5GZG0; F8W1P5; Q8N4R7; Q9NVL2;
DE   RecName: Full=DCC-interacting protein 13-beta;
DE            Short=Dip13-beta;
DE   AltName: Full=Adapter protein containing PH domain, PTB domain and leucine zipper motif 2;
GN   Name=APPL2; Synonyms=DIP13B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   DPA1_HUMAN              Reviewed;         260 AA.
AC   P20036; A9YWH7; B9UKH4; O19722; O46883; P01905; P79554; Q2Q060;
AC   Q2Q061; Q5EY03; Q5STP1; Q6DQK4; Q9BCQ1; Q9TPX3; Q9XS10;
DE   RecName: Full=HLA class II histocompatibility antigen, DP alpha 1 chain;
DE   AltName: Full=DP(W3);
DE   AltName: Full=DP(W4);
DE   AltName: Full=HLA-SB alpha chain;
DE   AltName: Full=MHC class II DP3-alpha;
DE   AltName: Full=MHC class II DPA1;
DE   Flags: Precursor;
GN   Name=HLA-DPA1; Synonyms=HLA-DP1A, HLASB;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DPB1_HUMAN              Reviewed;         258 AA.
AC   P04440; A0PFJ7; A5I886; A8YPB3; B5U8B4; B7VF80; B7VF87; B8ZX68;
AC   B8ZYT0; B9W5S8; B9W6F7; B9W6F9; C0MPP5; C0MPQ2; C0MPQ3; C0MPQ5;
AC   C0MPQ6; C0MPQ7; C4R9J5; C5IZL1; O00259; O19698; O19700; O19702;
AC   O19749; O46884; O77952; O98215; O98216; O98217; O98218; O98219;
AC   O98222; O98223; P01916; P04232; P13763; P79493; P79608; Q0P0L4;
AC   Q0ZFN3; Q14279; Q27S71; Q29682; Q29684; Q29698; Q29714; Q29775;
AC   Q29776; Q29778; Q29779; Q29781; Q29827; Q29828; Q29879; Q29880;
AC   Q29898; Q29977; Q2MGW3; Q30015; Q30031; Q30032; Q30033; Q30034;
AC   Q30050; Q30051; Q30052; Q30053; Q30054; Q30055; Q30174; Q4GY31;
AC   Q4JHD8; Q5ENE0; Q5ENE1; Q5ENW3; Q5EP46; Q5EP47; Q5EP49; Q5EP51;
AC   Q5EP52; Q5EP53; Q5EP56; Q5I4H8; Q5I4H9; Q5ISH4; Q5ISH5; Q5SQ73;
AC   Q5STP2; Q5YLA6; Q6IVX1; Q6LBX2; Q6LBX3; Q6LBX4; Q6LBX5; Q6LBX6;
AC   Q6LBX7; Q6PWX6; Q6TAS4; Q714U1; Q714U2; Q7YQ10; Q860Z7; Q8HWL7;
AC   Q8HWT5; Q8SNC4; Q95HC1; Q95IT7; Q95IT8; Q9BD13; Q9GIM2; Q9GIM4;
AC   Q9GIX6; Q9GJ41; Q9MY67; Q9TNT7; Q9TQE2; Q9XS11; Q9XS12;
DE   RecName: Full=HLA class II histocompatibility antigen, DP beta 1 chain;
DE   AltName: Full=HLA class II histocompatibility antigen, DP(W4) beta chain;
DE   AltName: Full=MHC class II antigen DPB1;
DE   Flags: Precursor;
GN   Name=HLA-DPB1; Synonyms=HLA-DP1B;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DPCA2_HUMAN             Reviewed;         172 AA.
AC   Q86SG4; Q495B5; Q86SH8; Q8N8I5;
DE   RecName: Full=Putative Dresden prostate carcinoma protein 2;
DE            Short=D-PCa-2;
DE   AltName: Full=High mobility group nucleosome-binding domain-containing protein 2 pseudogene 46;
GN   Name=HMGN2P46; Synonyms=C15orf21;
//
ID   DPCD_HUMAN              Reviewed;         203 AA.
AC   Q9BVM2; A8K289; Q6QNL3; Q8N5R1; Q9UFY6;
DE   RecName: Full=Protein DPCD;
GN   Name=DPCD;
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0021670; P:lateral ventricle development; IEA:Ensembl.
DR   GO; GO:0060972; P:left/right pattern formation; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0021678; P:third ventricle development; IEA:Ensembl.
//
ID   DPCR1_HUMAN             Reviewed;         517 AA.
AC   Q3MIW9; C9IZC0; Q658M7; Q8WYN2;
DE   RecName: Full=Diffuse panbronchiolitis critical region protein 1;
DE   Flags: Precursor;
GN   Name=DPCR1; Synonyms=C6orf37, PBLT;
//
ID   DPEP1_HUMAN             Reviewed;         411 AA.
AC   P16444; D3DX80; Q96AK2;
DE   RecName: Full=Dipeptidase 1;
DE            EC=3.4.13.19;
DE   AltName: Full=Dehydropeptidase-I;
DE   AltName: Full=Microsomal dipeptidase;
DE   AltName: Full=Renal dipeptidase;
DE            Short=hRDP;
DE   Flags: Precursor;
GN   Name=DPEP1; Synonyms=MDP, RDP;
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IEA:InterPro.
DR   GO; GO:0034235; F:GPI anchor binding; ISS:UniProtKB.
DR   GO; GO:0070573; F:metallodipeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008235; F:metalloexopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0016999; P:antibiotic metabolic process; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0072340; P:cellular lactam catabolic process; TAS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0071732; P:cellular response to nitric oxide; ISS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DPEP2_HUMAN             Reviewed;         486 AA.
AC   Q9H4A9; B2RCF8; Q6UX92; Q8TC95;
DE   RecName: Full=Dipeptidase 2;
DE            EC=3.4.13.19;
DE   Flags: Precursor;
GN   Name=DPEP2; ORFNames=UNQ284/PRO323;
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DPEP3_HUMAN             Reviewed;         488 AA.
AC   Q9H4B8; B3KQ48; Q6PEZ5; Q6UXE4;
DE   RecName: Full=Dipeptidase 3;
DE            EC=3.4.13.19;
DE   Flags: Precursor;
GN   Name=DPEP3; ORFNames=UNQ834/PRO1772;
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
//
ID   DPF1_HUMAN              Reviewed;         380 AA.
AC   Q92782; B3KSY8; Q08AJ0;
DE   RecName: Full=Zinc finger protein neuro-d4;
DE   AltName: Full=BRG1-associated factor 45B;
DE            Short=BAF45B;
DE   AltName: Full=D4, zinc and double PHD fingers family 1;
GN   Name=DPF1; Synonyms=BAF45B, NEUD4;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DPF3_HUMAN              Reviewed;         378 AA.
AC   Q92784; A8MSI3; Q32UJ0; Q6P9E6; Q6ZT41; Q9H7Y5;
DE   RecName: Full=Zinc finger protein DPF3;
DE   AltName: Full=BRG1-associated factor 45C;
DE            Short=BAF45C;
DE   AltName: Full=Zinc finger protein cer-d4;
GN   Name=DPF3; Synonyms=BAF45C, CERD4;
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DPH1_HUMAN              Reviewed;         443 AA.
AC   Q9BZG8; D3DTI3; Q16439; Q4VBA2; Q9BTW7; Q9UCY0;
DE   RecName: Full=Diphthamide biosynthesis protein 1;
DE   AltName: Full=DPH1 homolog;
DE            Short=HsDph1;
DE   AltName: Full=Diphthamide biosynthesis protein 2 homolog-like 1;
DE            Short=DPH-like 1;
DE            Short=DPH2-like 1;
DE            Short=Diphthamide biosynthesis protein 2-like;
DE   AltName: Full=Ovarian cancer-associated gene 1 protein;
GN   Name=DPH1; Synonyms=DPH2L, DPH2L1, OVCA1;
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   DPH2_HUMAN              Reviewed;         489 AA.
AC   Q9BQC3; A8MVC9; B2RDE3; O60623;
DE   RecName: Full=Diphthamide biosynthesis protein 2;
DE   AltName: Full=DPH2 homolog;
DE            Short=HsDph2;
DE   AltName: Full=Diphthamide biosynthesis protein 2 homolog-like 2;
DE            Short=DPH2-like 2;
GN   Name=DPH2; Synonyms=DPH2L2;
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:UniProtKB-UniPathway.
//
ID   DPH3B_HUMAN             Reviewed;          78 AA.
AC   Q9H4G8;
DE   RecName: Full=Putative DPH3 homolog B;
DE   AltName: Full=CSL-type zinc finger-containing protein 1;
GN   Name=DPH3P1; Synonyms=C20orf143, DPH3B, ZCSL1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   DPH3_HUMAN              Reviewed;          82 AA.
AC   Q96FX2;
DE   RecName: Full=DPH3 homolog;
DE   AltName: Full=CSL-type zinc finger-containing protein 2;
DE   AltName: Full=DelGEF-interacting protein 1;
DE            Short=DelGIP1;
GN   Name=DPH3; Synonyms=DESR1, ZCSL2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; ISS:UniProtKB.
DR   GO; GO:0051099; P:positive regulation of binding; IDA:UniProtKB.
//
ID   DPH5_HUMAN              Reviewed;         285 AA.
AC   Q9H2P9; A8JZY6; D3DT62; Q9P017; Q9P0I4; Q9Y319;
DE   RecName: Full=Diphthine synthase;
DE            EC=2.1.1.98;
DE   AltName: Full=Diphthamide biosynthesis methyltransferase;
GN   Name=DPH5; ORFNames=AD-018, CGI-30, HSPC143, NPD015;
DR   GO; GO:0004164; F:diphthine synthase activity; NAS:UniProtKB.
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; NAS:UniProtKB.
//
ID   DPH6_HUMAN              Reviewed;         267 AA.
AC   Q7L8W6; B3KWG1; Q96HJ6;
DE   RecName: Full=Diphthine--ammonia ligase;
DE            EC=6.3.1.14;
DE   AltName: Full=ATP-binding domain-containing protein 4;
DE   AltName: Full=Diphthamide synthase;
DE   AltName: Full=Diphthamide synthetase;
DE   AltName: Full=Protein DPH6 homolog;
GN   Name=DPH6; Synonyms=ATPBD4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017178; F:diphthine-ammonia ligase activity; TAS:UniProtKB.
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; TAS:UniProtKB.
//
ID   DPH7_HUMAN              Reviewed;         452 AA.
AC   Q9BTV6; Q96AB7;
DE   RecName: Full=Diphthamide biosynthesis protein 7;
DE   AltName: Full=WD repeat-containing protein 85;
GN   Name=DPH7; Synonyms=C9orf112, WDR85;
DR   GO; GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IMP:UniProtKB.
//
ID   DPM1_HUMAN              Reviewed;         260 AA.
AC   O60762; O15157; Q6IB78; Q96HK0;
DE   RecName: Full=Dolichol-phosphate mannosyltransferase subunit 1;
DE            EC=2.4.1.83;
DE   AltName: Full=Dolichol-phosphate mannose synthase subunit 1;
DE            Short=DPM synthase subunit 1;
DE   AltName: Full=Dolichyl-phosphate beta-D-mannosyltransferase subunit 1;
DE   AltName: Full=Mannose-P-dolichol synthase subunit 1;
DE            Short=MPD synthase subunit 1;
GN   Name=DPM1;
DR   GO; GO:0043178; F:alcohol binding; IEA:Ensembl.
DR   GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; IDA:HGNC.
DR   GO; GO:0005537; F:mannose binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019348; P:dolichol metabolic process; IDA:MGI.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0019673; P:GDP-mannose metabolic process; IEA:Ensembl.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0035268; P:protein mannosylation; IDA:HGNC.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0035269; P:protein O-linked mannosylation; IDA:HGNC.
//
ID   DPM2_HUMAN              Reviewed;          84 AA.
AC   O94777; Q5XKK9; Q6FGH3;
DE   RecName: Full=Dolichol phosphate-mannose biosynthesis regulatory protein;
DE   AltName: Full=Dolichol-phosphate mannose synthase subunit 2;
DE            Short=DPM synthase subunit 2;
GN   Name=DPM2; ORFNames=My026;
DR   GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019348; P:dolichol metabolic process; IEA:Ensembl.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0035269; P:protein O-linked mannosylation; TAS:HGNC.
DR   GO; GO:0031647; P:regulation of protein stability; IPI:UniProtKB.
//
ID   DPM3_HUMAN              Reviewed;          92 AA.
AC   Q9P2X0; Q5SR62; Q5SR63; Q9BXN4; Q9BXN5;
DE   RecName: Full=Dolichol-phosphate mannosyltransferase subunit 3;
DE   AltName: Full=Dolichol-phosphate mannose synthase subunit 3;
DE            Short=DPM synthase subunit 3;
DE   AltName: Full=Dolichyl-phosphate beta-D-mannosyltransferase subunit 3;
DE   AltName: Full=Mannose-P-dolichol synthase subunit 3;
DE            Short=MPD synthase subunit 3;
DE   AltName: Full=Prostin-1;
GN   Name=DPM3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018406; P:protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan; TAS:HGNC.
DR   GO; GO:0035268; P:protein mannosylation; TAS:HGNC.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0035269; P:protein O-linked mannosylation; TAS:HGNC.
DR   GO; GO:0031647; P:regulation of protein stability; IPI:UniProtKB.
//
ID   DPOA2_HUMAN             Reviewed;         598 AA.
AC   Q14181; Q9BPV3;
DE   RecName: Full=DNA polymerase alpha subunit B;
DE   AltName: Full=DNA polymerase alpha 70 kDa subunit;
GN   Name=POLA2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; IBA:RefGenome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
//
ID   DPOD1_HUMAN             Reviewed;        1107 AA.
AC   P28340; Q8NER3; Q96H98;
DE   RecName: Full=DNA polymerase delta catalytic subunit;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase subunit delta p125;
GN   Name=POLD1; Synonyms=POLD;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IBA:RefGenome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006287; P:base-excision repair, gap-filling; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0045004; P:DNA replication proofreading; IBA:RefGenome.
DR   GO; GO:0043137; P:DNA replication, removal of RNA primer; IBA:RefGenome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0055089; P:fatty acid homeostasis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IBA:GOC.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IMP:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.
DR   GO; GO:0009411; P:response to UV; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DPOD2_HUMAN             Reviewed;         469 AA.
AC   P49005; A4D2J4; B2R5S4;
DE   RecName: Full=DNA polymerase delta subunit 2;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase delta subunit p50;
GN   Name=POLD2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DPOD3_HUMAN             Reviewed;         466 AA.
AC   Q15054; B7ZAI6; Q32MZ9; Q32N00;
DE   RecName: Full=DNA polymerase delta subunit 3;
DE   AltName: Full=DNA polymerase delta subunit p66;
GN   Name=POLD3; Synonyms=KIAA0039;
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; NAS:UniProtKB.
DR   GO; GO:0006298; P:mismatch repair; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IMP:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DPOD4_HUMAN             Reviewed;         107 AA.
AC   Q9HCU8; F5H506;
DE   RecName: Full=DNA polymerase delta subunit 4;
DE   AltName: Full=DNA polymerase delta subunit p12;
GN   Name=POLD4; Synonyms=POLDS;
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DPOE1_HUMAN             Reviewed;        2286 AA.
AC   Q07864; Q13533; Q86VH9;
DE   RecName: Full=DNA polymerase epsilon catalytic subunit A;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase II subunit A;
GN   Name=POLE; Synonyms=POLE1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IMP:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006287; P:base-excision repair, gap-filling; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:Reactome.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IMP:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DPOE2_HUMAN             Reviewed;         527 AA.
AC   P56282; A0AV55; A4FU92; A4LBB7; A6NH58; B4DDE6; O43560;
DE   RecName: Full=DNA polymerase epsilon subunit 2;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase II subunit 2;
DE   AltName: Full=DNA polymerase epsilon subunit B;
GN   Name=POLE2; Synonyms=DPE2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   DPOE3_HUMAN             Reviewed;         147 AA.
AC   Q9NRF9; Q5W0U1; Q8N758; Q8NCE5; Q9NR32;
DE   RecName: Full=DNA polymerase epsilon subunit 3;
DE            EC=2.7.7.7;
DE   AltName: Full=Arsenic-transactivated protein;
DE            Short=AsTP;
DE   AltName: Full=Chromatin accessibility complex 17 kDa protein;
DE            Short=CHRAC-17;
DE            Short=HuCHRAC17;
DE   AltName: Full=DNA polymerase II subunit 3;
DE   AltName: Full=DNA polymerase epsilon subunit p17;
GN   Name=POLE3; Synonyms=CHRAC17;
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:GOC.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
//
ID   DPOE4_HUMAN             Reviewed;         117 AA.
AC   Q9NR33; Q53TR2;
DE   RecName: Full=DNA polymerase epsilon subunit 4;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase II subunit 4;
DE   AltName: Full=DNA polymerase epsilon subunit p12;
GN   Name=POLE4;
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:GOC.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
//
ID   DPOG1_HUMAN             Reviewed;        1239 AA.
AC   P54098; Q8NFM2; Q92515;
DE   RecName: Full=DNA polymerase subunit gamma-1;
DE            EC=2.7.7.7;
DE   AltName: Full=Mitochondrial DNA polymerase catalytic subunit;
DE   AltName: Full=PolG-alpha;
GN   Name=POLG; Synonyms=MDP1, POLG1, POLGA;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IDA:MGI.
DR   GO; GO:0004527; F:exonuclease activity; IEA:Ensembl.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006287; P:base-excision repair, gap-filling; IDA:MGI.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IEA:Ensembl.
//
ID   DPOG2_HUMAN             Reviewed;         485 AA.
AC   Q9UHN1; O00419; Q0IJ81; Q96GW2; Q9UK35; Q9UK94;
DE   RecName: Full=DNA polymerase subunit gamma-2, mitochondrial;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase gamma accessory 55 kDa subunit;
DE            Short=p55;
DE   AltName: Full=Mitochondrial DNA polymerase accessory subunit;
DE   AltName: Full=MtPolB;
DE   AltName: Full=PolG-beta;
DE   Flags: Precursor;
GN   Name=POLG2; Synonyms=MTPOLB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
//
ID   DPOLA_HUMAN             Reviewed;        1462 AA.
AC   P09884; Q86UQ7;
DE   RecName: Full=DNA polymerase alpha catalytic subunit;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase alpha catalytic subunit p180;
GN   Name=POLA1; Synonyms=POLA;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IBA:RefGenome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001882; F:nucleoside binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; IDA:UniProtKB.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IDA:GOC.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IMP:UniProtKB.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006273; P:lagging strand elongation; IDA:UniProtKB.
DR   GO; GO:0006272; P:leading strand elongation; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000084; P:mitotic S phase; IDA:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IBA:GOC.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0019985; P:translesion synthesis; IBA:RefGenome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DPOLB_HUMAN             Reviewed;         335 AA.
AC   P06746; B2RC78; Q3KP48; Q6FI34;
DE   RecName: Full=DNA polymerase beta;
DE            EC=2.7.7.7;
DE            EC=4.2.99.-;
GN   Name=POLB;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0016829; F:lyase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0006287; P:base-excision repair, gap-filling; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
//
ID   DPOLL_HUMAN             Reviewed;         575 AA.
AC   Q9UGP5; D3DR76; Q5JQP5; Q6NUM2; Q9HA10; Q9HB35;
DE   RecName: Full=DNA polymerase lambda;
DE            Short=Pol Lambda;
DE            EC=2.7.7.7;
DE            EC=4.2.99.-;
DE   AltName: Full=DNA polymerase beta-2;
DE            Short=Pol beta2;
DE   AltName: Full=DNA polymerase kappa;
GN   Name=POLL;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; NAS:GOC.
DR   GO; GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; NAS:UniProtKB.
//
ID   DPOLM_HUMAN             Reviewed;         494 AA.
AC   Q9NP87; D3DVK4;
DE   RecName: Full=DNA-directed DNA/RNA polymerase mu;
DE            Short=Pol Mu;
DE            EC=2.7.7.7;
DE   AltName: Full=Terminal transferase;
GN   Name=POLM; Synonyms=polmu;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Ensembl.
//
ID   DPOLN_HUMAN             Reviewed;         900 AA.
AC   Q7Z5Q5; A2A336; B4E158; Q4TTW4; Q6ZNF4;
DE   RecName: Full=DNA polymerase nu;
DE            EC=2.7.7.7;
GN   Name=POLN;
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IDA:GOC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProt.
DR   GO; GO:0036297; P:interstrand cross-link repair; IMP:UniProt.
DR   GO; GO:0019985; P:translesion synthesis; IDA:UniProt.
//
ID   DPOLQ_HUMAN             Reviewed;        2590 AA.
AC   O75417; O95160; Q6VMB5;
DE   RecName: Full=DNA polymerase theta;
DE            EC=2.7.7.7;
DE   AltName: Full=DNA polymerase eta;
GN   Name=POLQ; Synonyms=POLH;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0043142; F:single-stranded DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IDA:GOC.
//
ID   DPOLZ_HUMAN             Reviewed;        3130 AA.
AC   O60673; O43214; Q5TC33;
DE   RecName: Full=DNA polymerase zeta catalytic subunit;
DE            EC=2.7.7.7;
DE   AltName: Full=Protein reversionless 3-like;
DE            Short=REV3-like;
DE            Short=hREV3;
GN   Name=REV3L; Synonyms=POLZ, REV3;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0019985; P:translesion synthesis; IBA:RefGenome.
//
ID   DPP10_HUMAN             Reviewed;         796 AA.
AC   Q8N608; A8K1Q2; J3KPP2; J3KQ46; Q0GLB8; Q53QT3; Q53S86; Q53SL8;
AC   Q53SS4; Q6TTV4; Q86YR9; Q9P236;
DE   RecName: Full=Inactive dipeptidyl peptidase 10;
DE   AltName: Full=Dipeptidyl peptidase IV-related protein 3;
DE            Short=DPRP-3;
DE   AltName: Full=Dipeptidyl peptidase X;
DE            Short=DPP X;
DE   AltName: Full=Dipeptidyl peptidase-like protein 2;
DE            Short=DPL2;
GN   Name=DPP10; Synonyms=DPRP3, KIAA1492;
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
//
ID   DPP2_HUMAN              Reviewed;         492 AA.
AC   Q9UHL4; A8K7U7; Q5VSF1; Q969X4;
DE   RecName: Full=Dipeptidyl peptidase 2;
DE            EC=3.4.14.2;
DE   AltName: Full=Dipeptidyl aminopeptidase II;
DE   AltName: Full=Dipeptidyl peptidase 7;
DE   AltName: Full=Dipeptidyl peptidase II;
DE            Short=DPP II;
DE   AltName: Full=Quiescent cell proline dipeptidase;
DE   Flags: Precursor;
GN   Name=DPP7; Synonyms=DPP2, QPP;
DR   GuidetoPHARMACOLOGY; 1605; -.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IEA:Ensembl.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   DPP3_HUMAN              Reviewed;         737 AA.
AC   Q9NY33; B2RDB5; B4DLX4; F5H8L6; O95748; Q969H2; Q9BV67; Q9HAL6;
DE   RecName: Full=Dipeptidyl peptidase 3;
DE            EC=3.4.14.4;
DE   AltName: Full=Dipeptidyl aminopeptidase III;
DE   AltName: Full=Dipeptidyl arylamidase III;
DE   AltName: Full=Dipeptidyl peptidase III;
DE            Short=DPP III;
DE   AltName: Full=Enkephalinase B;
GN   Name=DPP3;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   DPP4_HUMAN              Reviewed;         766 AA.
AC   P27487; Q53TN1;
DE   RecName: Full=Dipeptidyl peptidase 4;
DE            EC=3.4.14.5;
DE   AltName: Full=ADABP;
DE   AltName: Full=Adenosine deaminase complexing protein 2;
DE            Short=ADCP-2;
DE   AltName: Full=Dipeptidyl peptidase IV;
DE            Short=DPP IV;
DE   AltName: Full=T-cell activation antigen CD26;
DE   AltName: Full=TP103;
DE   AltName: CD_antigen=CD26;
DE   Contains:
DE     RecName: Full=Dipeptidyl peptidase 4 membrane form;
DE     AltName: Full=Dipeptidyl peptidase IV membrane form;
DE   Contains:
DE     RecName: Full=Dipeptidyl peptidase 4 soluble form;
DE     AltName: Full=Dipeptidyl peptidase IV soluble form;
GN   Name=DPP4; Synonyms=ADCP2, CD26;
DR   GuidetoPHARMACOLOGY; 1612; -.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0043542; P:endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0010716; P:negative regulation of extracellular matrix disassembly; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0033632; P:regulation of cell-cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; IDA:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
//
ID   DPP6_HUMAN              Reviewed;         865 AA.
AC   P42658;
DE   RecName: Full=Dipeptidyl aminopeptidase-like protein 6;
DE   AltName: Full=DPPX;
DE   AltName: Full=Dipeptidyl aminopeptidase-related protein;
DE   AltName: Full=Dipeptidyl peptidase 6;
DE   AltName: Full=Dipeptidyl peptidase IV-like protein;
DE   AltName: Full=Dipeptidyl peptidase VI;
DE            Short=DPP VI;
GN   Name=DPP6;
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; TAS:ProtInc.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0043266; P:regulation of potassium ion transport; IEA:Ensembl.
//
ID   DPP8_HUMAN              Reviewed;         898 AA.
AC   Q6V1X1; Q7Z4C8; Q7Z4D3; Q7Z4E1; Q8IWG7; Q8NEM5; Q96JX1; Q9HBM2;
AC   Q9HBM3; Q9HBM4; Q9HBM5; Q9NXF4;
DE   RecName: Full=Dipeptidyl peptidase 8;
DE            Short=DP8;
DE            EC=3.4.14.5;
DE   AltName: Full=Dipeptidyl peptidase IV-related protein 1;
DE            Short=DPRP-1;
DE   AltName: Full=Dipeptidyl peptidase VIII;
DE            Short=DPP VIII;
DE   AltName: Full=Prolyl dipeptidase DPP8;
GN   Name=DPP8; Synonyms=DPRP1; ORFNames=MSTP097, MSTP135, MSTP141;
DR   GuidetoPHARMACOLOGY; 2356; -.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; NAS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   DPP9_HUMAN              Reviewed;         863 AA.
AC   Q86TI2; O75273; O75868; Q1ZZB8; Q6AI37; Q6UAL0; Q6ZMT2; Q6ZNJ5;
AC   Q8N2J7; Q8N3F5; Q8WXD8; Q96NT8; Q9BVR3;
DE   RecName: Full=Dipeptidyl peptidase 9;
DE            Short=DP9;
DE            EC=3.4.14.5;
DE   AltName: Full=Dipeptidyl peptidase IV-related protein 2;
DE            Short=DPRP-2;
DE   AltName: Full=Dipeptidyl peptidase IX;
DE            Short=DPP IX;
DE   AltName: Full=Dipeptidyl peptidase-like protein 9;
DE            Short=DPLP9;
GN   Name=DPP9; Synonyms=DPRP2;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
//
ID   DPPA2_HUMAN             Reviewed;         298 AA.
AC   Q7Z7J5; Q8WVF0;
DE   RecName: Full=Developmental pluripotency-associated protein 2;
DE   AltName: Full=Pluripotent embryonic stem cell-related gene 1 protein;
GN   Name=DPPA2; Synonyms=PESCRG1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0031060; P:regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DPPA3_HUMAN             Reviewed;         159 AA.
AC   Q6W0C5; Q0P5U3; Q6JZS6;
DE   RecName: Full=Developmental pluripotency-associated protein 3;
DE   AltName: Full=Stella-related protein;
GN   Name=DPPA3; Synonyms=STELLAR;
DR   GO; GO:0035064; F:methylated histone binding; ISS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0040016; P:embryonic cleavage; IEA:Ensembl.
DR   GO; GO:1901536; P:negative regulation of DNA demethylation; ISS:UniProtKB.
DR   GO; GO:0044726; P:protection of DNA demethylation of female pronucleus; ISS:UniProtKB.
DR   GO; GO:2000653; P:regulation of genetic imprinting; ISS:UniProtKB.
//
ID   DPPA4_HUMAN             Reviewed;         304 AA.
AC   Q7L190; A8K4M7; Q9H9N5; Q9NVI6;
DE   RecName: Full=Developmental pluripotency-associated protein 4;
GN   Name=DPPA4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DPPA5_HUMAN             Reviewed;         116 AA.
AC   A6NC42; B2RPQ7;
DE   RecName: Full=Developmental pluripotency-associated 5 protein;
DE            Short=hDPPA5;
DE   AltName: Full=Embryonal stem cell-specific gene 1 protein;
DE            Short=ESG-1;
GN   Name=DPPA5; Synonyms=ESG1;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   DPRX_HUMAN              Reviewed;         191 AA.
AC   A6NFQ7;
DE   RecName: Full=Divergent paired-related homeobox;
GN   Name=DPRX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DPS1_HUMAN              Reviewed;         415 AA.
AC   Q5T2R2; Q53F75; Q6P473; Q86WQ8; Q9Y2W5;
DE   RecName: Full=Decaprenyl-diphosphate synthase subunit 1;
DE            EC=2.5.1.91;
DE   AltName: Full=All-trans-decaprenyl-diphosphate synthase subunit 1;
DE   AltName: Full=Decaprenyl pyrophosphate synthase subunit 1;
DE   AltName: Full=Trans-prenyltransferase 1;
DE            Short=TPT 1;
GN   Name=PDSS1; Synonyms=DPS1, TPRT;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:HGNC.
DR   GO; GO:0000010; F:trans-hexaprenyltranstransferase activity; IEA:Ensembl.
DR   GO; GO:0050347; F:trans-octaprenyltranstransferase activity; IEA:Ensembl.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IDA:HGNC.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IDA:HGNC.
//
ID   DPTOR_HUMAN             Reviewed;         409 AA.
AC   Q8TB45; B2RCL9; B4DN97; E7EV87; Q96EQ1; Q9H0R7; Q9H894; Q9HA07;
DE   RecName: Full=DEP domain-containing mTOR-interacting protein;
DE   AltName: Full=DEP domain-containing protein 6;
GN   Name=DEPTOR; Synonyms=DEPDC6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0045792; P:negative regulation of cell size; IMP:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:2001236; P:regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
//
ID   DPY30_HUMAN             Reviewed;          99 AA.
AC   Q9C005; D6W578;
DE   RecName: Full=Protein dpy-30 homolog;
DE   AltName: Full=Dpy-30-like protein;
DE            Short=Dpy-30L;
GN   Name=DPY30;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DPYD_HUMAN              Reviewed;        1025 AA.
AC   Q12882; A2RRQ2; A2RRQ3; A8K5A2; A8MWG9; B1AN21; E9PFN1; Q16694;
AC   Q16761; Q32NB0; Q96HL6; Q96TH1;
DE   RecName: Full=Dihydropyrimidine dehydrogenase [NADP(+)];
DE            Short=DHPDHase;
DE            Short=DPD;
DE            EC=1.3.1.2;
DE   AltName: Full=Dihydrothymine dehydrogenase;
DE   AltName: Full=Dihydrouracil dehydrogenase;
DE   Flags: Precursor;
GN   Name=DPYD;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004158; F:dihydroorotate oxidase activity; IEA:InterPro.
DR   GO; GO:0017113; F:dihydropyrimidine dehydrogenase (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050661; F:NADP binding; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019483; P:beta-alanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006145; P:purine nucleobase catabolic process; IMP:UniProtKB.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IMP:UniProtKB.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006214; P:thymidine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006210; P:thymine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006222; P:UMP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006212; P:uracil catabolic process; IDA:UniProtKB.
//
ID   DPYL1_HUMAN             Reviewed;         572 AA.
AC   Q14194; A0EJG6; Q13024; Q4W5F1; Q96TC8;
DE   RecName: Full=Dihydropyrimidinase-related protein 1;
DE            Short=DRP-1;
DE   AltName: Full=Collapsin response mediator protein 1;
DE            Short=CRMP-1;
DE   AltName: Full=Unc-33-like phosphoprotein 3;
DE            Short=ULIP-3;
GN   Name=CRMP1; Synonyms=DPYSL1, ULIP3;
DR   GO; GO:0016812; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IEA:InterPro.
//
ID   DPYL2_HUMAN             Reviewed;         572 AA.
AC   Q16555; A8K5H2; B4DR31; D3DSS7; O00424;
DE   RecName: Full=Dihydropyrimidinase-related protein 2;
DE            Short=DRP-2;
DE   AltName: Full=Collapsin response mediator protein 2;
DE            Short=CRMP-2;
DE   AltName: Full=N2A3;
DE   AltName: Full=Unc-33-like phosphoprotein 2;
DE            Short=ULIP-2;
GN   Name=DPYSL2; Synonyms=CRMP2, ULIP2;
DR   GO; GO:0004157; F:dihydropyrimidinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0014049; P:positive regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IEA:InterPro.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0048489; P:synaptic vesicle transport; IEA:Ensembl.
//
ID   DPYL3_HUMAN             Reviewed;         570 AA.
AC   Q14195; B3SXQ8; Q93012;
DE   RecName: Full=Dihydropyrimidinase-related protein 3;
DE            Short=DRP-3;
DE   AltName: Full=Collapsin response mediator protein 4;
DE            Short=CRMP-4;
DE   AltName: Full=Unc-33-like phosphoprotein 1;
DE            Short=ULIP-1;
GN   Name=DPYSL3; Synonyms=CRMP4, DRP3, ULIP, ULIP1;
DR   GO; GO:0035374; F:chondroitin sulfate binding; ISS:UniProtKB.
DR   GO; GO:0016812; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; IEA:InterPro.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
DR   GO; GO:0051764; P:actin crosslink formation; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IEA:InterPro.
DR   GO; GO:0048678; P:response to axon injury; ISS:UniProtKB.
//
ID   DPYL4_HUMAN             Reviewed;         572 AA.
AC   O14531; B2RMQ1; D3DRG5; O00240; Q5T0Q7;
DE   RecName: Full=Dihydropyrimidinase-related protein 4;
DE            Short=DRP-4;
DE   AltName: Full=Collapsin response mediator protein 3;
DE            Short=CRMP-3;
DE   AltName: Full=UNC33-like phosphoprotein 4;
DE            Short=ULIP-4;
GN   Name=DPYSL4; Synonyms=CRMP3, ULIP4;
DR   GO; GO:0016812; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IEA:InterPro.
//
ID   DPYL5_HUMAN             Reviewed;         564 AA.
AC   Q9BPU6; Q8TCL6; Q9NQC4; Q9NRY9;
DE   RecName: Full=Dihydropyrimidinase-related protein 5;
DE            Short=DRP-5;
DE   AltName: Full=CRMP3-associated molecule;
DE            Short=CRAM;
DE   AltName: Full=Collapsin response mediator protein 5;
DE            Short=CRMP-5;
DE   AltName: Full=UNC33-like phosphoprotein 6;
DE            Short=ULIP-6;
GN   Name=DPYSL5; Synonyms=CRMP5, ULIP6;
DR   GO; GO:0016812; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   DPYS_HUMAN              Reviewed;         519 AA.
AC   Q14117;
DE   RecName: Full=Dihydropyrimidinase;
DE            Short=DHP;
DE            Short=DHPase;
DE            EC=3.5.2.2;
DE   AltName: Full=Dihydropyrimidine amidohydrolase;
DE   AltName: Full=Hydantoinase;
GN   Name=DPYS;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0004157; F:dihydropyrimidinase activity; IDA:UniProtKB.
DR   GO; GO:0002059; F:thymine binding; IEA:Ensembl.
DR   GO; GO:0002058; F:uracil binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0019482; P:beta-alanine metabolic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
DR   GO; GO:0006208; P:pyrimidine nucleobase catabolic process; IDA:UniProtKB.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006210; P:thymine catabolic process; ISS:UniProtKB.
DR   GO; GO:0006212; P:uracil catabolic process; IDA:UniProtKB.
//
ID   DQA1_HUMAN              Reviewed;         254 AA.
AC   P01909; O19630; O19706; P01907; P01908; P04225; P04226; P05536;
AC   P79553; Q06751; Q29876; Q29994; Q2Q6Y6; Q2Q6Y7; Q2Q6Y8; Q2WCM3;
AC   Q30064; Q30067; Q30068; Q30070; Q30071; Q30072; Q30073; Q30086;
AC   Q30101; Q5Y7D5; Q5Y7F5; Q6ICU6; Q6PR46; Q6QDB1; Q860W2; Q860W4;
AC   Q9BD37; Q9TPM3; Q9UM31;
DE   RecName: Full=HLA class II histocompatibility antigen, DQ alpha 1 chain;
DE   AltName: Full=DC-1 alpha chain;
DE   AltName: Full=DC-alpha;
DE   AltName: Full=HLA-DCA;
DE   AltName: Full=MHC class II DQA1;
DE   Flags: Precursor;
GN   Name=HLA-DQA1;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DQA2_HUMAN              Reviewed;         255 AA.
AC   P01906; A2BF37; B0V0E7; O19789; Q5SQ94; Q5SR04;
DE   RecName: Full=HLA class II histocompatibility antigen, DQ alpha 2 chain;
DE   AltName: Full=DX alpha chain;
DE   AltName: Full=HLA class II histocompatibility antigen, DQ(6) alpha chain;
DE   AltName: Full=HLA-DQA1;
DE   AltName: Full=MHC class II DQA2;
DE   Flags: Precursor;
GN   Name=HLA-DQA2; Synonyms=HLA-DXA;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DQB1_HUMAN              Reviewed;         261 AA.
AC   P01920; A1KR27; A2RPH3; A4Q9R4; A4USG2; A4USG5; A6N8I7; A9YQA0;
AC   B0S7Y7; B1A0K6; B1GXI3; B3VLT3; B5BLN7; B7VU69; C0MQ34; C0MQ35;
AC   C8ZL52; C8ZLJ8; C8ZLJ9; C9DRQ3; O19708; O19713; O19724; O62861;
AC   O78046; O78221; O78223; O98034; O98201; P01917; P01918; P01919;
AC   P03992; P05537; P79482; P79526; P79544; P79551; Q08GC8; Q09035;
AC   Q0E4V9; Q1M312; Q29731; Q29877; Q29884; Q29915; Q29966; Q2P9N3;
AC   Q2QK85; Q30061; Q30075; Q30076; Q30080; Q30081; Q30082; Q30083;
AC   Q30084; Q30089; Q30095; Q31633; Q38I47; Q45UE3; Q4QZB5; Q53I44;
AC   Q564J6; Q5G841; Q5ISH1; Q5ISH3; Q5W1E1; Q5Y7G8; Q643R4; Q6B9X1;
AC   Q70VH8; Q7YP69; Q8HWH0; Q8MH58; Q8SNB4; Q8SND1; Q8SP70; Q8WMA3;
AC   Q9BD17; Q9MYH2; Q9TPA9; Q9XRY6; Q9XRY7; Q9XRZ2;
DE   RecName: Full=HLA class II histocompatibility antigen, DQ beta 1 chain;
DE   AltName: Full=MHC class II antigen DQB1;
DE   Flags: Precursor;
GN   Name=HLA-DQB1; Synonyms=HLA-DQB;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; IDA:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DQX1_HUMAN              Reviewed;         717 AA.
AC   Q8TE96; Q6B017; Q8NAM8;
DE   RecName: Full=ATP-dependent RNA helicase DQX1;
DE            EC=3.6.4.12;
DE   AltName: Full=DEAQ box polypeptide 1;
GN   Name=DQX1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   DQB2_HUMAN              Reviewed;         268 AA.
AC   P05538; A6NIA5; Q29826; Q29870; Q29871; Q29872; Q29873; Q5SR06;
DE   RecName: Full=HLA class II histocompatibility antigen, DQ beta 2 chain;
DE   AltName: Full=HLA class II histocompatibility antigen, DX beta chain;
DE   AltName: Full=MHC class II antigen DQB2;
DE   Flags: Precursor;
GN   Name=HLA-DQB2; Synonyms=HLA-DXB;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DR4L2_HUMAN             Reviewed;         230 AA.
AC   Q6PKH6; Q3YLD4;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 4-like 2;
DE            EC=1.1.-.-;
DE   Flags: Precursor;
GN   Name=DHRS4L2;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DR4L1_HUMAN             Reviewed;         281 AA.
AC   P0CG22;
DE   RecName: Full=Putative dehydrogenase/reductase SDR family member 4-like 2;
DE            EC=1.1.-.-;
GN   Name=DHRS4L1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DR9C7_HUMAN             Reviewed;         313 AA.
AC   Q8NEX9; B3KVB4;
DE   RecName: Full=Short-chain dehydrogenase/reductase family 9C member 7;
DE            EC=1.1.1.-;
DE   AltName: Full=Orphan short-chain dehydrogenase/reductase;
DE            Short=SDR-O;
DE   AltName: Full=RDH-S;
GN   Name=SDR9C7; Synonyms=RDHS, SDRO;
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
//
ID   DRAM1_HUMAN             Reviewed;         238 AA.
AC   Q8N682; Q7L3E3; Q9NUN1;
DE   RecName: Full=DNA damage-regulated autophagy modulator protein 1;
DE   AltName: Full=Damage-regulated autophagy modulator;
GN   Name=DRAM1; Synonyms=DRAM;
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0097194; P:execution phase of apoptosis; IC:UniProtKB.
//
ID   DRAM2_HUMAN             Reviewed;         266 AA.
AC   Q6UX65; B3SUG9; Q4VWF6; Q86VD3; Q8NBQ4;
DE   RecName: Full=DNA damage-regulated autophagy modulator protein 2;
DE   AltName: Full=Transmembrane protein 77;
GN   Name=DRAM2; Synonyms=TMEM77; ORFNames=PSEC0031, UNQ154/PRO180;
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0097194; P:execution phase of apoptosis; IC:UniProtKB.
//
ID   DRAXI_HUMAN             Reviewed;         349 AA.
AC   Q8NBI3; B6EV15; Q5SNX0; Q6UWK8;
DE   RecName: Full=Draxin;
DE   AltName: Full=Dorsal inhibitory axon guidance protein;
DE   AltName: Full=Dorsal repulsive axon guidance protein;
DE   AltName: Full=Neucrin;
DE   Flags: Precursor;
GN   Name=DRAXIN; Synonyms=C1orf187; ORFNames=PSEC0258, UNQ3119/PRO10268;
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0021528; P:commissural neuron differentiation in spinal cord; ISS:UniProtKB.
DR   GO; GO:0021516; P:dorsal spinal cord development; ISS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; ISS:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DRA_HUMAN               Reviewed;         254 AA.
AC   P01903; A2BET4; Q30160; Q6IAZ1; Q861I2; Q9TP70;
DE   RecName: Full=HLA class II histocompatibility antigen, DR alpha chain;
DE   AltName: Full=MHC class II antigen DRA;
DE   Flags: Precursor;
GN   Name=HLA-DRA; Synonyms=HLA-DRA1;
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DRB3_HUMAN              Reviewed;         266 AA.
AC   P79483; A0ZXY9; A7MA46; B5AU12; B5AU13; B5AU14; B8YAC6; C6H115;
AC   C6H116; O02875; O19590; O46701; O46794; O78049; O78162; P01913;
AC   P79663; Q29721; Q29809; Q2PPD0; Q30144; Q507L8; Q5SP44; Q5STE0;
AC   Q6YJU6; Q70M87; Q7YQ62; Q860I9; Q8SP69; Q8WLT7; Q8WLT8; Q95359;
AC   Q95HM8; Q95IE5; Q96H16; Q9BCP3; Q9BD18; Q9MYA4; Q9MYH3; Q9MYH4;
AC   Q9TP01; Q9TP02; Q9TPB5; Q9TQ21; Q9UIN3; Q9UIN5;
DE   RecName: Full=HLA class II histocompatibility antigen, DR beta 3 chain;
DE   AltName: Full=MHC class II antigen DRB3;
DE   Flags: Precursor;
GN   Name=HLA-DRB3;
DR   GO; GO:0032395; F:MHC class II receptor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DRB5_HUMAN              Reviewed;         266 AA.
AC   Q30154; B2RBV6; C7C4X3; O00157; O00283; O46700; Q29703; Q29787;
AC   Q29788; Q30126; Q30150; Q30199; Q6SJR2; Q7M2H9; Q8HWS7; Q8WLR5;
AC   Q9MY54; Q9XRX6;
DE   RecName: Full=HLA class II histocompatibility antigen, DR beta 5 chain;
DE   AltName: Full=DR beta-5;
DE   AltName: Full=DR2-beta-2;
DE   AltName: Full=Dw2;
DE   AltName: Full=MHC class II antigen DRB5;
DE   Flags: Precursor;
GN   Name=HLA-DRB5;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DRB4_HUMAN              Reviewed;         266 AA.
AC   P13762; B0S863; O78042; P79664; Q29889; Q30163; Q6TLK6; Q860N4;
AC   Q861F3; Q8WLT9; Q9BS54;
DE   RecName: Full=HLA class II histocompatibility antigen, DR beta 4 chain;
DE   AltName: Full=MHC class II antigen DRB4;
DE   Flags: Precursor;
GN   Name=HLA-DRB4;
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   DRC1_HUMAN              Reviewed;         740 AA.
AC   Q96MC2; A8K1N8; Q53R91; Q53TA3; Q8NDI5;
DE   RecName: Full=Dynein regulatory complex protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 164;
GN   Name=DRC1; Synonyms=C2orf39, CCDC164;
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IMP:UniProtKB.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IMP:UniProtKB.
//
ID   DRD1_HUMAN              Reviewed;         446 AA.
AC   P21728; B2RA44; Q4QRJ0;
DE   RecName: Full=D(1A) dopamine receptor;
DE   AltName: Full=Dopamine D1 receptor;
GN   Name=DRD1;
DR   GuidetoPHARMACOLOGY; 214; -.
DR   GO; GO:0035240; F:dopamine binding; IMP:BHF-UCL.
DR   GO; GO:0004952; F:dopamine neurotransmitter receptor activity; IDA:MGI.
DR   GO; GO:0001588; F:dopamine neurotransmitter receptor activity, coupled via Gs; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IDA:BHF-UCL.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; ISS:BHF-UCL.
DR   GO; GO:0014002; P:astrocyte development; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.
DR   GO; GO:0021853; P:cerebral cortex GABAergic interneuron migration; ISS:BHF-UCL.
DR   GO; GO:0001661; P:conditioned taste aversion; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0042417; P:dopamine metabolic process; IC:BHF-UCL.
DR   GO; GO:0015872; P:dopamine transport; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; IDA:BHF-UCL.
DR   GO; GO:0046323; P:glucose import; IEA:Ensembl.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0046959; P:habituation; IEA:Ensembl.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0007617; P:mating behavior; ISS:BHF-UCL.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0035106; P:operant conditioning; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; IEA:Ensembl.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; ISS:BHF-UCL.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0051584; P:regulation of dopamine uptake involved in synaptic transmission; IC:BHF-UCL.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; ISS:BHF-UCL.
DR   GO; GO:0046960; P:sensitization; IEA:Ensembl.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
DR   GO; GO:0019226; P:transmission of nerve impulse; ISS:BHF-UCL.
DR   GO; GO:0042311; P:vasodilation; IEA:InterPro.
DR   GO; GO:0008542; P:visual learning; ISS:BHF-UCL.
//
ID   DRD2_HUMAN              Reviewed;         443 AA.
AC   P14416; Q9NZR3; Q9UPA9;
DE   RecName: Full=D(2) dopamine receptor;
DE   AltName: Full=Dopamine D2 receptor;
GN   Name=DRD2;
DR   GuidetoPHARMACOLOGY; 215; -.
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0035240; F:dopamine binding; IEA:Ensembl.
DR   GO; GO:0001591; F:dopamine neurotransmitter receptor activity, coupled via Gi/Go; IDA:BHF-UCL.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0015459; F:potassium channel regulator activity; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0021984; P:adenohypophysis development; ISS:BHF-UCL.
DR   GO; GO:0007195; P:adenylate cyclase-inhibiting dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007628; P:adult walking behavior; ISS:BHF-UCL.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:BHF-UCL.
DR   GO; GO:0008306; P:associative learning; ISS:BHF-UCL.
DR   GO; GO:0031223; P:auditory behavior; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0048148; P:behavioral response to cocaine; ISS:BHF-UCL.
DR   GO; GO:0048149; P:behavioral response to ethanol; ISS:BHF-UCL.
DR   GO; GO:0048755; P:branching morphogenesis of a nerve; ISS:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IC:BHF-UCL.
DR   GO; GO:0021853; P:cerebral cortex GABAergic interneuron migration; ISS:BHF-UCL.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0042417; P:dopamine metabolic process; IC:BHF-UCL.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IEA:Ensembl.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; ISS:BHF-UCL.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IDA:BHF-UCL.
DR   GO; GO:0045776; P:negative regulation of blood pressure; ISS:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0042321; P:negative regulation of circadian sleep/wake cycle, sleep; IEA:Ensembl.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0060160; P:negative regulation of dopamine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0033602; P:negative regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; ISS:BHF-UCL.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:1901386; P:negative regulation of voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0001976; P:neurological system process involved in regulation of systemic arterial blood pressure; ISS:BHF-UCL.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0021769; P:orbitofrontal cortex development; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; ISS:BHF-UCL.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; ISS:BHF-UCL.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IGI:MGI.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051586; P:positive regulation of dopamine uptake involved in synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; ISS:BHF-UCL.
DR   GO; GO:1900273; P:positive regulation of long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0035810; P:positive regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.
DR   GO; GO:0008104; P:protein localization; ISS:BHF-UCL.
DR   GO; GO:0030814; P:regulation of cAMP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051584; P:regulation of dopamine uptake involved in synaptic transmission; IC:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0090325; P:regulation of locomotion involved in locomotory behavior; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; ISS:BHF-UCL.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:Ensembl.
DR   GO; GO:0043266; P:regulation of potassium ion transport; ISS:BHF-UCL.
DR   GO; GO:0002028; P:regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0051823; P:regulation of synapse structural plasticity; IEA:Ensembl.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:BHF-UCL.
DR   GO; GO:0001975; P:response to amphetamine; ISS:BHF-UCL.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; ISS:BHF-UCL.
DR   GO; GO:0034776; P:response to histamine; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0014854; P:response to inactivity; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; ISS:BHF-UCL.
DR   GO; GO:0043278; P:response to morphine; ISS:BHF-UCL.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:BHF-UCL.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; ISS:BHF-UCL.
DR   GO; GO:0008542; P:visual learning; ISS:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   DRD3_HUMAN              Reviewed;         400 AA.
AC   P35462; A1A4V5; Q4VBM8;
DE   RecName: Full=D(3) dopamine receptor;
DE   AltName: Full=Dopamine D3 receptor;
GN   Name=DRD3;
DR   GuidetoPHARMACOLOGY; 216; -.
DR   GO; GO:0035240; F:dopamine binding; IEA:Ensembl.
DR   GO; GO:0001591; F:dopamine neurotransmitter receptor activity, coupled via Gi/Go; IDA:BHF-UCL.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046717; P:acid secretion; ISS:BHF-UCL.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007195; P:adenylate cyclase-inhibiting dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:BHF-UCL.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEP:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0042417; P:dopamine metabolic process; IC:BHF-UCL.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035483; P:gastric emptying; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; NAS:BHF-UCL.
DR   GO; GO:0007611; P:learning or memory; NAS:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; ISS:BHF-UCL.
DR   GO; GO:0050883; P:musculoskeletal movement, spinal reflex action; ISS:BHF-UCL.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IDA:BHF-UCL.
DR   GO; GO:0045776; P:negative regulation of blood pressure; ISS:BHF-UCL.
DR   GO; GO:0060160; P:negative regulation of dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; ISS:BHF-UCL.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0032416; P:negative regulation of sodium:proton antiporter activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0060161; P:positive regulation of dopamine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; ISS:BHF-UCL.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060134; P:prepulse inhibition; IMP:BHF-UCL.
DR   GO; GO:0002016; P:regulation of blood volume by renin-angiotensin; IEA:Ensembl.
DR   GO; GO:0030814; P:regulation of cAMP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; IEA:Ensembl.
DR   GO; GO:0014059; P:regulation of dopamine secretion; ISS:BHF-UCL.
DR   GO; GO:0051584; P:regulation of dopamine uptake involved in synaptic transmission; IC:BHF-UCL.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0090325; P:regulation of locomotion involved in locomotory behavior; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; ISS:BHF-UCL.
DR   GO; GO:0034776; P:response to histamine; IDA:BHF-UCL.
DR   GO; GO:0043278; P:response to morphine; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; NAS:BHF-UCL.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; ISS:BHF-UCL.
//
ID   DRD4_HUMAN              Reviewed;         467 AA.
AC   P21917; B0M0J7; Q7Z7Q5; Q8NGM5;
DE   RecName: Full=D(4) dopamine receptor;
DE   AltName: Full=D(2C) dopamine receptor;
DE   AltName: Full=Dopamine D4 receptor;
GN   Name=DRD4;
DR   GuidetoPHARMACOLOGY; 217; -.
DR   GO; GO:0035240; F:dopamine binding; IDA:BHF-UCL.
DR   GO; GO:0004952; F:dopamine neurotransmitter receptor activity; IDA:BHF-UCL.
DR   GO; GO:0001591; F:dopamine neurotransmitter receptor activity, coupled via Gi/Go; IDA:BHF-UCL.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0015459; F:potassium channel regulator activity; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:BHF-UCL.
DR   GO; GO:0007195; P:adenylate cyclase-inhibiting dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008344; P:adult locomotory behavior; ISS:BHF-UCL.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:BHF-UCL.
DR   GO; GO:0001662; P:behavioral fear response; NAS:BHF-UCL.
DR   GO; GO:0048148; P:behavioral response to cocaine; ISS:BHF-UCL.
DR   GO; GO:0048149; P:behavioral response to ethanol; TAS:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IC:BHF-UCL.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0042417; P:dopamine metabolic process; IC:BHF-UCL.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042596; P:fear response; ISS:BHF-UCL.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IDA:BHF-UCL.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:1901386; P:negative regulation of voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0008355; P:olfactory learning; IEA:Ensembl.
DR   GO; GO:0009648; P:photoperiodism; IEA:Ensembl.
DR   GO; GO:0051586; P:positive regulation of dopamine uptake involved in synaptic transmission; IC:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IDA:BHF-UCL.
DR   GO; GO:0060406; P:positive regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0032417; P:positive regulation of sodium:proton antiporter activity; IDA:BHF-UCL.
DR   GO; GO:0050848; P:regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; ISS:BHF-UCL.
DR   GO; GO:0034776; P:response to histamine; IDA:BHF-UCL.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007614; P:short-term memory; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; NAS:BHF-UCL.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
//
ID   DRD5_HUMAN              Reviewed;         477 AA.
AC   P21918; B2R9S3; Q8NEQ8;
DE   RecName: Full=D(1B) dopamine receptor;
DE   AltName: Full=D(5) dopamine receptor;
DE   AltName: Full=D1beta dopamine receptor;
DE   AltName: Full=Dopamine D5 receptor;
GN   Name=DRD5; Synonyms=DRD1B, DRD1L2;
DR   GuidetoPHARMACOLOGY; 218; -.
DR   GO; GO:0035240; F:dopamine binding; IDA:UniProtKB.
DR   GO; GO:0004952; F:dopamine neurotransmitter receptor activity; IDA:UniProtKB.
DR   GO; GO:0001588; F:dopamine neurotransmitter receptor activity, coupled via Gs; TAS:BHF-UCL.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:BHF-UCL.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:BHF-UCL.
DR   GO; GO:0071870; P:cellular response to catecholamine stimulus; IDA:BHF-UCL.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0033861; P:negative regulation of NAD(P)H oxidase activity; IDA:UniProtKB.
DR   GO; GO:0001994; P:norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0045762; P:positive regulation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0045924; P:regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0001992; P:regulation of systemic arterial blood pressure by vasopressin; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0046960; P:sensitization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; NAS:UniProtKB.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   DREB_HUMAN              Reviewed;         649 AA.
AC   Q16643; A8MV58; B2RBG0; Q9UFZ5;
DE   RecName: Full=Drebrin;
DE   AltName: Full=Developmentally-regulated brain protein;
GN   Name=DBN1; Synonyms=D0S117E;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0005522; F:profilin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007015; P:actin filament organization; ISS:UniProtKB.
DR   GO; GO:0010643; P:cell communication by chemical coupling; IEA:Ensembl.
DR   GO; GO:0010644; P:cell communication by electrical coupling; IEA:Ensembl.
DR   GO; GO:0032507; P:maintenance of protein location in cell; IEA:Ensembl.
DR   GO; GO:0061351; P:neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0050773; P:regulation of dendrite development; NAS:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; NAS:UniProtKB.
//
ID   DRG1_HUMAN              Reviewed;         367 AA.
AC   Q9Y295; B2RDS8; Q6FGP8; Q8WW69; Q9UGF2;
DE   RecName: Full=Developmentally-regulated GTP-binding protein 1;
DE            Short=DRG-1;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 3;
DE            Short=NEDD-3;
GN   Name=DRG1; Synonyms=NEDD3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   DRG2_HUMAN              Reviewed;         364 AA.
AC   P55039; B2R8G5; Q53Y50; Q9BWB2;
DE   RecName: Full=Developmentally-regulated GTP-binding protein 2;
DE            Short=DRG-2;
GN   Name=DRG2;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   DRGX_HUMAN              Reviewed;         263 AA.
AC   A6NNA5;
DE   RecName: Full=Dorsal root ganglia homeobox protein;
DE   AltName: Full=Paired-related homeobox protein-like 1;
GN   Name=DRGX; Synonyms=PRRXL1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DRIC1_HUMAN             Reviewed;         229 AA.
AC   Q6PGQ1; Q6ICJ8; Q6P4I3; Q9NU31;
DE   RecName: Full=Aspartate-rich protein 1;
GN   Name=DRICH1; Synonyms=C22orf43;
//
ID   DRP2_HUMAN              Reviewed;         957 AA.
AC   Q13474; A6ZKI5; A8K1B0; B1B1F3; B4DIZ0;
DE   RecName: Full=Dystrophin-related protein 2;
DE            Short=DRP-2;
GN   Name=DRP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
//
ID   DRS7C_HUMAN             Reviewed;         312 AA.
AC   A6NNS2; B7ZW74; B9EJH3;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 7C;
DE            EC=1.1.-.-;
DE   Flags: Precursor;
GN   Name=DHRS7C;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IEA:Ensembl.
//
ID   DRS7B_HUMAN             Reviewed;         325 AA.
AC   Q6IAN0; B5MEF4; Q6UX59; Q9BTF9; Q9UFM6; Q9Y3A1;
DE   RecName: Full=Dehydrogenase/reductase SDR family member 7B;
DE            EC=1.1.-.-;
GN   Name=DHRS7B; ORFNames=CGI-93, UNQ212/PRO238;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   DS13A_HUMAN             Reviewed;         188 AA.
AC   Q6B8I1; Q96J67;
DE   RecName: Full=Dual specificity protein phosphatase 13 isoform A;
DE            Short=DUSP13A;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Branching-enzyme interacting DSP;
DE   AltName: Full=Muscle-restricted DSP;
DE            Short=MDSP;
GN   Name=DUSP13; Synonyms=BEDP, DUSP13A, MDSP;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
//
ID   DS13B_HUMAN             Reviewed;         198 AA.
AC   Q9UII6; A8K776; A8K782; B3KPY1; B3KXT0; B4DUK0; Q5JSC6; Q6IAR0;
AC   Q96GC2;
DE   RecName: Full=Dual specificity protein phosphatase 13 isoform B;
DE            Short=DUSP13B;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase SKRP4;
DE   AltName: Full=Testis- and skeletal-muscle-specific DSP;
GN   Name=DUSP13; Synonyms=DUSP13B, TMDP;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   DSA2D_HUMAN             Reviewed;         133 AA.
AC   C9JQL5;
DE   RecName: Full=Putative dispanin subfamily A member 2d;
DE            Short=DSPA2d;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   DSC10_HUMAN             Reviewed;          87 AA.
AC   P59022; Q52LN2;
DE   RecName: Full=Down syndrome critical region protein 10;
GN   Name=DSCR10;
//
ID   DSC1_HUMAN              Reviewed;         894 AA.
AC   Q08554; Q9HB01;
DE   RecName: Full=Desmocollin-1;
DE   AltName: Full=Cadherin family member 1;
DE   AltName: Full=Desmosomal glycoprotein 2/3;
DE            Short=DG2/DG3;
DE   Flags: Precursor;
GN   Name=DSC1; Synonyms=CDHF1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   DSC2_HUMAN              Reviewed;         901 AA.
AC   Q02487;
DE   RecName: Full=Desmocollin-2;
DE   AltName: Full=Cadherin family member 2;
DE   AltName: Full=Desmocollin-3;
DE   AltName: Full=Desmosomal glycoprotein II;
DE   AltName: Full=Desmosomal glycoprotein III;
DE   Flags: Precursor;
GN   Name=DSC2; Synonyms=CDHF2, DSC3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0086042; P:cardiac muscle cell-cardiac muscle cell adhesion; IMP:UniProt.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   DSC3_HUMAN              Reviewed;         896 AA.
AC   Q14574; A6NN35; Q14200; Q9HAZ9;
DE   RecName: Full=Desmocollin-3;
DE   AltName: Full=Cadherin family member 3;
DE   AltName: Full=Desmocollin-4;
DE   AltName: Full=HT-CP;
DE   Flags: Precursor;
GN   Name=DSC3; Synonyms=CDHF3, DSC4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
//
ID   DSCAM_HUMAN             Reviewed;        2012 AA.
AC   O60469; O60468;
DE   RecName: Full=Down syndrome cell adhesion molecule;
DE   AltName: Full=CHD2;
DE   Flags: Precursor;
GN   Name=DSCAM;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0070593; P:dendrite self-avoidance; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0060060; P:post-embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
//
ID   DSCL1_HUMAN             Reviewed;        2053 AA.
AC   Q8TD84; Q76MU9; Q8IZY3; Q8IZY4; Q8WXU7; Q9ULT7;
DE   RecName: Full=Down syndrome cell adhesion molecule-like protein 1;
DE   AltName: Full=Down syndrome cell adhesion molecule 2;
DE   Flags: Precursor;
GN   Name=DSCAML1; Synonyms=DSCAM2, KIAA1132;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; NAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IDA:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; NAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0070593; P:dendrite self-avoidance; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; NAS:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IDA:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
//
ID   DSCR3_HUMAN             Reviewed;         297 AA.
AC   O14972; B2R6T8; D3DSH4; Q2TAY6;
DE   RecName: Full=Down syndrome critical region protein 3;
DE   AltName: Full=Down syndrome critical region protein A;
GN   Name=DSCR3; Synonyms=DCRA, DSCRA;
//
ID   DSCR4_HUMAN             Reviewed;         118 AA.
AC   P56555; Q4VB31;
DE   RecName: Full=Down syndrome critical region protein 4;
DE   AltName: Full=Down syndrome critical region protein B;
GN   Name=DSCR4; Synonyms=DCRB, DSCRB;
//
ID   DSCR6_HUMAN             Reviewed;         190 AA.
AC   P57055;
DE   RecName: Full=Protein ripply3;
DE   AltName: Full=Down syndrome critical region protein 6;
GN   Name=RIPPLY3; Synonyms=DSCR6;
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DSCR8_HUMAN             Reviewed;          97 AA.
AC   Q96T75; Q8N3X0; Q8NDY5; Q96B46;
DE   RecName: Full=Down syndrome critical region protein 8;
DE   AltName: Full=Cancer/testis antigen 25;
DE            Short=CT25;
DE   AltName: Full=Malignant melanoma-associated protein 1;
DE            Short=MMA-1;
DE   AltName: Full=Protein MTAG2;
GN   Name=DSCR8; Synonyms=C21orf65, MTAG2;
//
ID   DSCR9_HUMAN             Reviewed;         149 AA.
AC   P59020; B2R8P8;
DE   RecName: Full=Down syndrome critical region protein 9;
GN   Name=DSCR9;
//
ID   DSEL_HUMAN              Reviewed;        1212 AA.
AC   Q8IZU8; Q17RH1; Q6P5Z3;
DE   RecName: Full=Dermatan-sulfate epimerase-like protein;
DE            EC=5.1.-.-;
DE   Flags: Precursor;
GN   Name=DSEL; Synonyms=C18orf4, NCAG1;
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DSE_HUMAN               Reviewed;         958 AA.
AC   Q9UL01; Q5R3K6;
DE   RecName: Full=Dermatan-sulfate epimerase;
DE            Short=DS epimerase;
DE            EC=5.1.3.19;
DE   AltName: Full=Chondroitin-glucuronate 5-epimerase;
DE   AltName: Full=Squamous cell carcinoma antigen recognized by T-cells 2;
DE            Short=SART-2;
DE   Flags: Precursor;
GN   Name=DSE; Synonyms=SART2;
DR   GO; GO:0047757; F:chondroitin-glucuronate 5-epimerase activity; IDA:HGNC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DSG1_HUMAN              Reviewed;        1049 AA.
AC   Q02413;
DE   RecName: Full=Desmoglein-1;
DE   AltName: Full=Cadherin family member 4;
DE   AltName: Full=Desmosomal glycoprotein 1;
DE            Short=DG1;
DE            Short=DGI;
DE   AltName: Full=Pemphigus foliaceus antigen;
DE   Flags: Precursor;
GN   Name=DSG1; Synonyms=CDHF4;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0015643; F:toxic substance binding; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007043; P:cell-cell junction assembly; NAS:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
//
ID   DSG2_HUMAN              Reviewed;        1118 AA.
AC   Q14126; Q4KKU6;
DE   RecName: Full=Desmoglein-2;
DE   AltName: Full=Cadherin family member 5;
DE   AltName: Full=HDGC;
DE   Flags: Precursor;
GN   Name=DSG2; Synonyms=CDHF5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   DSG3_HUMAN              Reviewed;         999 AA.
AC   P32926; A8K2V2;
DE   RecName: Full=Desmoglein-3;
DE   AltName: Full=130 kDa pemphigus vulgaris antigen;
DE            Short=PVA;
DE   AltName: Full=Cadherin family member 6;
DE   Flags: Precursor;
GN   Name=DSG3; Synonyms=CDHF6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   DSG4_HUMAN              Reviewed;        1040 AA.
AC   Q86SJ6; A2RUI1; Q6Y9L9; Q8IXV4;
DE   RecName: Full=Desmoglein-4;
DE   AltName: Full=Cadherin family member 13;
DE   Flags: Precursor;
GN   Name=DSG4; Synonyms=CDHF13;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
//
ID   DSN1_HUMAN              Reviewed;         356 AA.
AC   Q9H410; B4DWT2; E1P5U9; Q5JW55; Q5JW56; Q9H8P4;
DE   RecName: Full=Kinetochore-associated protein DSN1 homolog;
GN   Name=DSN1; Synonyms=C20orf172, MIS13;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   DSPP_HUMAN              Reviewed;        1301 AA.
AC   Q9NZW4; A8MUI0; O95815;
DE   RecName: Full=Dentin sialophosphoprotein;
DE   Contains:
DE     RecName: Full=Dentin phosphoprotein;
DE     AltName: Full=Dentin phosphophoryn;
DE              Short=DPP;
DE   Contains:
DE     RecName: Full=Dentin sialoprotein;
DE              Short=DSP;
DE   Flags: Precursor;
GN   Name=DSPP;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005518; F:collagen binding; TAS:ProtInc.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0071460; P:cellular response to cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   DSRAD_HUMAN             Reviewed;        1226 AA.
AC   P55265; B1AQQ9; B1AQR0; D3DV76; O15223; O43859; O43860; Q9BYM3;
AC   Q9BYM4;
DE   RecName: Full=Double-stranded RNA-specific adenosine deaminase;
DE            Short=DRADA;
DE            EC=3.5.4.37;
DE   AltName: Full=136 kDa double-stranded RNA-binding protein;
DE            Short=p136;
DE   AltName: Full=Interferon-inducible protein 4;
DE            Short=IFI-4;
DE   AltName: Full=K88DSRBP;
GN   Name=ADAR; Synonyms=ADAR1, DSRAD, G1P1, IFI4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006382; P:adenosine to inosine editing; IDA:UniProtKB.
DR   GO; GO:0016553; P:base conversion or substitution editing; IDA:MGI.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0016556; P:mRNA modification; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0044387; P:negative regulation of protein kinase activity by regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   DSS1_HUMAN              Reviewed;          70 AA.
AC   P60896; Q13437; Q61067;
DE   RecName: Full=26S proteasome complex subunit DSS1;
DE   AltName: Full=Deleted in split hand/split foot protein 1;
DE   AltName: Full=Split hand/foot deleted protein 1;
DE   AltName: Full=Split hand/foot malformation type 1 protein;
GN   Name=SHFM1; Synonyms=DSS1, SHFDG1;
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   DTBP1_HUMAN             Reviewed;         351 AA.
AC   Q96EV8; A8K3V3; Q5THY3; Q5THY4; Q96NV2; Q9H0U2; Q9H3J5;
DE   RecName: Full=Dysbindin;
DE   AltName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 8;
DE            Short=BLOC-1 subunit 8;
DE   AltName: Full=Dysbindin-1;
DE   AltName: Full=Dystrobrevin-binding protein 1;
DE   AltName: Full=Hermansky-Pudlak syndrome 7 protein;
DE            Short=HPS7 protein;
GN   Name=DTNBP1; Synonyms=BLOC1S8; ORFNames=My031;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060155; P:platelet dense granule organization; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0001956; P:positive regulation of neurotransmitter secretion; ISS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0060159; P:regulation of dopamine receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0014059; P:regulation of dopamine secretion; ISS:UniProtKB.
//
ID   DTD1_HUMAN              Reviewed;         209 AA.
AC   Q8TEA8; A8K5X5; D3DW37; Q496D1; Q5W184; Q8WXU8; Q9BW67; Q9H464;
AC   Q9H474;
DE   RecName: Full=D-tyrosyl-tRNA(Tyr) deacylase 1;
DE            EC=3.1.-.-;
DE   AltName: Full=DNA-unwinding element-binding protein B;
DE            Short=DUE-B;
DE   AltName: Full=Histidyl-tRNA synthase-related;
GN   Name=DTD1; Synonyms=C20orf88, DUEB, HARS2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019478; P:D-amino acid catabolic process; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   DTD2_HUMAN              Reviewed;         168 AA.
AC   Q96FN9; D3DS87;
DE   RecName: Full=Probable D-tyrosyl-tRNA(Tyr) deacylase 2;
DE            EC=3.1.-.-;
DE   AltName: Full=D-tyrosyl-tRNA deacylase 2;
GN   Name=DTD2; Synonyms=C14orf126;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0019478; P:D-amino acid catabolic process; IEA:InterPro.
//
ID   DTHD1_HUMAN             Reviewed;         781 AA.
AC   Q6ZMT9; B2RXK4; B4E2N7;
DE   RecName: Full=Death domain-containing protein 1;
GN   Name=DTHD1;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   DTL_HUMAN               Reviewed;         730 AA.
AC   Q9NZJ0; A8K8H8; D3DT98; Q5VT77; Q96SN0; Q9NW03; Q9NW34; Q9NWM5;
DE   RecName: Full=Denticleless protein homolog;
DE   AltName: Full=DDB1- and CUL4-associated factor 2;
DE   AltName: Full=Lethal(2) denticleless protein homolog;
DE   AltName: Full=Retinoic acid-regulated nuclear matrix-associated protein;
GN   Name=DTL; Synonyms=CDT2, CDW1, DCAF2, L2DTL, RAMP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0019985; P:translesion synthesis; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   DTNA_HUMAN              Reviewed;         743 AA.
AC   Q9Y4J8; A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; M0QYX6;
AC   M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498;
AC   Q13499; Q13500; Q59GK7; Q9BS59;
DE   RecName: Full=Dystrobrevin alpha;
DE            Short=DTN-A;
DE   AltName: Full=Alpha-dystrobrevin;
DE   AltName: Full=Dystrophin-related protein 3;
GN   Name=DTNA; Synonyms=DRP3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006941; P:striated muscle contraction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   DTNB_HUMAN              Reviewed;         627 AA.
AC   O60941; B7Z733; F5GZG4; G5E9F6; O43782; O60881; O75538; Q86VR4;
AC   Q96AW0; Q9UE14; Q9UE15; Q9UE16;
DE   RecName: Full=Dystrobrevin beta;
DE            Short=DTN-B;
DE   AltName: Full=Beta-dystrobrevin;
GN   Name=DTNB;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   DTWD1_HUMAN             Reviewed;         304 AA.
AC   Q8N5C7; Q567Q3; Q8WVG9; Q9NRU6;
DE   RecName: Full=DTW domain-containing protein 1;
GN   Name=DTWD1; ORFNames=MDS009;
//
ID   DTX1_HUMAN              Reviewed;         620 AA.
AC   Q86Y01; O60630; Q9BS04;
DE   RecName: Full=E3 ubiquitin-protein ligase DTX1;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein deltex-1;
DE            Short=Deltex1;
DE            Short=hDTX1;
GN   Name=DTX1;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005112; F:Notch binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IGI:UniProtKB.
DR   GO; GO:0045581; P:negative regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; IGI:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   DTX2_HUMAN              Reviewed;         622 AA.
AC   Q86UW9; Q6XM87; Q6XM88; Q96H69; Q9H890; Q9P200;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase DTX2;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein deltex-2;
DE            Short=Deltex2;
DE            Short=hDTX2;
DE   AltName: Full=RING finger protein 58;
GN   Name=DTX2; Synonyms=KIAA1528, RNF58;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   DTWD2_HUMAN             Reviewed;         298 AA.
AC   Q8NBA8;
DE   RecName: Full=DTW domain-containing protein 2;
GN   Name=DTWD2;
//
ID   DTX3L_HUMAN             Reviewed;         740 AA.
AC   Q8TDB6; B3KWH6; Q53ZZ3; Q5MJP7;
DE   RecName: Full=E3 ubiquitin-protein ligase DTX3L;
DE            EC=6.3.2.-;
DE   AltName: Full=B-lymphoma- and BAL-associated protein;
DE   AltName: Full=Protein deltex-3-like;
DE   AltName: Full=Rhysin-2;
DE            Short=Rhysin2;
GN   Name=DTX3L; Synonyms=BBAP;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
//
ID   DTX3_HUMAN              Reviewed;         347 AA.
AC   Q8N9I9; Q53ZZ2; Q8NAU6; Q8NDS8;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase DTX3;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein deltex-3;
DE            Short=Deltex3;
DE   AltName: Full=RING finger protein 154;
GN   Name=DTX3; Synonyms=RNF154;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   DTX4_HUMAN              Reviewed;         619 AA.
AC   Q9Y2E6; Q0VF38;
DE   RecName: Full=E3 ubiquitin-protein ligase DTX4;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein deltex-4;
DE            Short=Deltex4;
DE   AltName: Full=RING finger protein 155;
GN   Name=DTX4; Synonyms=KIAA0937, RNF155;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
//
ID   DU4L2_HUMAN             Reviewed;         424 AA.
AC   P0CJ85;
DE   RecName: Full=Double homeobox protein 4-like protein 2;
GN   Name=DUX4L2;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DU4L3_HUMAN             Reviewed;         424 AA.
AC   P0CJ86;
DE   RecName: Full=Double homeobox protein 4-like protein 3;
GN   Name=DUX4L3;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DU4L7_HUMAN             Reviewed;         424 AA.
AC   P0CJ90;
DE   RecName: Full=Double homeobox protein 4-like protein 7;
GN   Name=DUX4L7;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DU4L4_HUMAN             Reviewed;         422 AA.
AC   P0CJ87;
DE   RecName: Full=Double homeobox protein 4-like protein 4;
GN   Name=DUX4L4;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DU4L5_HUMAN             Reviewed;         424 AA.
AC   P0CJ88;
DE   RecName: Full=Double homeobox protein 4-like protein 5;
GN   Name=DUX4L5;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DU4L6_HUMAN             Reviewed;         424 AA.
AC   P0CJ89;
DE   RecName: Full=Double homeobox protein 4-like protein 6;
GN   Name=DUX4L6;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DUOX1_HUMAN             Reviewed;        1551 AA.
AC   Q9NRD9; A6NH28; Q14C94; Q6ZMB3; Q6ZR09; Q9NZC1;
DE   RecName: Full=Dual oxidase 1;
DE            EC=1.11.1.-;
DE            EC=1.6.3.1;
DE   AltName: Full=Large NOX 1;
DE   AltName: Full=Long NOX 1;
DE   AltName: Full=NADPH thyroid oxidase 1;
DE   AltName: Full=Thyroid oxidase 1;
DE   Flags: Precursor;
GN   Name=DUOX1; Synonyms=DUOX, LNOX1, THOX1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0016174; F:NAD(P)H oxidase activity; NAS:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; NAS:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042335; P:cuticle development; IMP:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; IDA:UniProtKB.
DR   GO; GO:0042554; P:superoxide anion generation; NAS:UniProtKB.
DR   GO; GO:0006590; P:thyroid hormone generation; IEA:UniProtKB-UniPathway.
//
ID   DUOX2_HUMAN             Reviewed;        1548 AA.
AC   Q9NRD8; A8MQ13; Q9NR02; Q9UHF9;
DE   RecName: Full=Dual oxidase 2;
DE            EC=1.11.1.-;
DE            EC=1.6.3.1;
DE   AltName: Full=Large NOX 2;
DE   AltName: Full=Long NOX 2;
DE   AltName: Full=NADH/NADPH thyroid oxidase p138-tox;
DE   AltName: Full=NADPH oxidase/peroxidase DUOX2;
DE   AltName: Full=NADPH thyroid oxidase 2;
DE   AltName: Full=Thyroid oxidase 2;
DE   AltName: Full=p138 thyroid oxidase;
DE   Flags: Precursor;
GN   Name=DUOX2; Synonyms=LNOX2, THOX2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0016174; F:NAD(P)H oxidase activity; IDA:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0048855; P:adenohypophysis morphogenesis; IEA:Ensembl.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0042335; P:cuticle development; ISS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006590; P:thyroid hormone generation; IEA:UniProtKB-UniPathway.
//
ID   DUPD1_HUMAN             Reviewed;         220 AA.
AC   Q68J44; B2RP93;
DE   RecName: Full=Dual specificity phosphatase DUPD1;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase 27;
GN   Name=DUPD1; Synonyms=DUSP27;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS10_HUMAN             Reviewed;         482 AA.
AC   Q9Y6W6; D3DTB4; Q6GSI4; Q9H9Z5;
DE   RecName: Full=Dual specificity protein phosphatase 10;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 5;
DE            Short=MAP kinase phosphatase 5;
DE            Short=MKP-5;
GN   Name=DUSP10; Synonyms=MKP5;
DR   GO; GO:0033549; F:MAP kinase phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0016791; F:phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:ProtInc.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
DR   GO; GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0002819; P:regulation of adaptive immune response; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   DUS11_HUMAN             Reviewed;         330 AA.
AC   O75319; B2RCT8; Q6AI47; Q9BWE3;
DE   RecName: Full=RNA/RNP complex-1-interacting phosphatase;
DE            EC=3.1.3.-;
DE   AltName: Full=Dual specificity protein phosphatase 11;
DE   AltName: Full=Phosphatase that interacts with RNA/RNP complex 1;
GN   Name=DUSP11; Synonyms=PIR1;
DR   GO; GO:0098519; F:nucleotide phosphatase activity, acting on free nucleotides; IMP:UniProtKB.
DR   GO; GO:0016791; F:phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004651; F:polynucleotide 5'-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0098507; P:polynucleotide 5' dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   DUS12_HUMAN             Reviewed;         340 AA.
AC   Q9UNI6; Q5VXA8;
DE   RecName: Full=Dual specificity protein phosphatase 12;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity tyrosine phosphatase YVH1;
GN   Name=DUSP12;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0033133; P:positive regulation of glucokinase activity; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS14_HUMAN             Reviewed;         198 AA.
AC   O95147;
DE   RecName: Full=Dual specificity protein phosphatase 14;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=MKP-1-like protein tyrosine phosphatase;
DE            Short=MKP-L;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 6;
DE            Short=MAP kinase phosphatase 6;
DE            Short=MKP-6;
GN   Name=DUSP14; Synonyms=MKP6;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IBA:RefGenome.
//
ID   DUS15_HUMAN             Reviewed;         295 AA.
AC   Q9H1R2; A6NH79; A8MVC8; Q5QP62; Q5QP63; Q5QP65; Q6PGN7; Q8N826;
AC   Q9BX24;
DE   RecName: Full=Dual specificity protein phosphatase 15;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=VH1-related member Y;
DE   AltName: Full=Vaccinia virus VH1-related dual-specific protein phosphatase Y;
GN   Name=DUSP15; Synonyms=C20orf57, VHY;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS16_HUMAN             Reviewed;         665 AA.
AC   Q9BY84; Q547C7; Q9C0G3;
DE   RecName: Full=Dual specificity protein phosphatase 16;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 7;
DE            Short=MAP kinase phosphatase 7;
DE            Short=MKP-7;
GN   Name=DUSP16; Synonyms=KIAA1700, MKP7;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016311; P:dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0000188; P:inactivation of MAPK activity; TAS:UniProtKB.
DR   GO; GO:0045204; P:MAPK export from nucleus; TAS:UniProtKB.
DR   GO; GO:0045209; P:MAPK phosphatase export from nucleus, leptomycin B sensitive; TAS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS18_HUMAN             Reviewed;         188 AA.
AC   Q8NEJ0; B3KPA4;
DE   RecName: Full=Dual specificity protein phosphatase 18;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Low molecular weight dual specificity phosphatase 20;
DE            Short=LMW-DSP20;
GN   Name=DUSP18; Synonyms=LMWDSP20;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
//
ID   DUS19_HUMAN             Reviewed;         217 AA.
AC   Q8WTR2; B2RA79; Q547H4; Q8WYN4;
DE   RecName: Full=Dual specificity protein phosphatase 19;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase TS-DSP1;
DE   AltName: Full=Low molecular weight dual specificity phosphatase 3;
DE            Short=LMW-DSP3;
DE   AltName: Full=Protein phosphatase SKRP1;
DE   AltName: Full=Stress-activated protein kinase pathway-regulating phosphatase 1;
DE            Short=SAPK pathway-regulating phosphatase 1;
GN   Name=DUSP19; Synonyms=DUSP17, LMWDSP3, SKRP1;
DR   GO; GO:0008579; F:JUN kinase phosphatase activity; IBA:RefGenome.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; ISS:BHF-UCL.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; ISS:BHF-UCL.
DR   GO; GO:0030295; F:protein kinase activator activity; ISS:BHF-UCL.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008330; F:protein tyrosine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007254; P:JNK cascade; IBA:RefGenome.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; ISS:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; ISS:BHF-UCL.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; ISS:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS1L_HUMAN             Reviewed;         473 AA.
AC   Q6P1R4; A6NHV4; Q96AI3;
DE   RecName: Full=tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like;
DE            EC=1.3.1.-;
DE   AltName: Full=tRNA-dihydrouridine synthase 1-like;
GN   Name=DUS1L;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
//
ID   DUS1_HUMAN              Reviewed;         367 AA.
AC   P28562; D3DQL9; Q2V508;
DE   RecName: Full=Dual specificity protein phosphatase 1;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase hVH1;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 1;
DE            Short=MAP kinase phosphatase 1;
DE            Short=MKP-1;
DE   AltName: Full=Protein-tyrosine phosphatase CL100;
GN   Name=DUSP1; Synonyms=CL100, MKP1, PTPN10, VH1;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008330; F:protein tyrosine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0001706; P:endoderm formation; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0051447; P:negative regulation of meiotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0090266; P:regulation of mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
//
ID   DUS21_HUMAN             Reviewed;         190 AA.
AC   Q9H596; Q0VDA6; Q6IAJ6; Q6YDQ8;
DE   RecName: Full=Dual specificity protein phosphatase 21;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Low molecular weight dual specificity phosphatase 21;
DE            Short=LMW-DSP21;
GN   Name=DUSP21; Synonyms=LMWDSP21;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
//
ID   DUS22_HUMAN             Reviewed;         184 AA.
AC   Q9NRW4; B4DK56; Q59GW2; Q5VWR2; Q96AR1;
DE   RecName: Full=Dual specificity protein phosphatase 22;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=JNK-stimulatory phosphatase-1;
DE            Short=JSP-1;
DE   AltName: Full=Low molecular weight dual specificity phosphatase 2;
DE            Short=LMW-DSP2;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase x;
DE            Short=MAP kinase phosphatase x;
DE            Short=MKP-x;
GN   Name=DUSP22; Synonyms=JSP1, LMWDSP2, MKPX;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
//
ID   DUS23_HUMAN             Reviewed;         150 AA.
AC   Q9BVJ7; Q9NX48;
DE   RecName: Full=Dual specificity protein phosphatase 23;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Low molecular mass dual specificity phosphatase 3;
DE            Short=LDP-3;
DE   AltName: Full=VH1-like phosphatase Z;
GN   Name=DUSP23; Synonyms=LDP3, VHZ;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
//
ID   DUS26_HUMAN             Reviewed;         211 AA.
AC   Q9BV47; D3DSV8; Q9BTW0;
DE   RecName: Full=Dual specificity protein phosphatase 26;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase SKRP3;
DE   AltName: Full=Low-molecular-mass dual-specificity phosphatase 4;
DE            Short=DSP-4;
DE            Short=LDP-4;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 8;
DE            Short=MAP kinase phosphatase 8;
DE            Short=MKP-8;
DE   AltName: Full=Novel amplified gene in thyroid anaplastic cancer;
GN   Name=DUSP26; Synonyms=DUSP24, LDP4, MKP8, NATA1, SKRP3;
DR   GO; GO:0002039; F:p53 binding; IPI:UniProt.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProt.
DR   GO; GO:0004647; F:phosphoserine phosphatase activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProt.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:UniProt.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProt.
DR   GO; GO:0044387; P:negative regulation of protein kinase activity by regulation of protein phosphorylation; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProt.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IMP:GOC.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProt.
DR   GO; GO:1902310; P:positive regulation of peptidyl-serine dephosphorylation; IDA:UniProt.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProt.
//
ID   DUS27_HUMAN             Reviewed;        1158 AA.
AC   Q5VZP5; A0AUM4; Q9C074;
DE   RecName: Full=Inactive dual specificity phosphatase 27;
GN   Name=DUSP27;
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS28_HUMAN             Reviewed;         176 AA.
AC   Q4G0W2;
DE   RecName: Full=Dual specificity phosphatase 28;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
GN   Name=DUSP28;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IBA:RefGenome.
//
ID   DUS2L_HUMAN             Reviewed;         493 AA.
AC   Q9NX74; A8K3G3; Q4H4D9;
DE   RecName: Full=tRNA-dihydrouridine(20) synthase [NAD(P)+]-like;
DE            EC=1.3.1.-;
DE   AltName: Full=Dihydrouridine synthase 2;
DE   AltName: Full=Up-regulated in lung cancer protein 8;
DE            Short=URLC8;
DE   AltName: Full=tRNA-dihydrouridine synthase 2-like;
DE            Short=hDUS2;
GN   Name=DUS2; Synonyms=DUS2L;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:GOC.
//
ID   DUS2_HUMAN              Reviewed;         314 AA.
AC   Q05923; Q53T45;
DE   RecName: Full=Dual specificity protein phosphatase 2;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase PAC-1;
GN   Name=DUSP2; Synonyms=PAC1;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0008330; F:protein tyrosine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0001706; P:endoderm formation; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
//
ID   DUS3L_HUMAN             Reviewed;         650 AA.
AC   Q96G46; Q96HM5; Q9BSU4; Q9H877; Q9NPR1;
DE   RecName: Full=tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like;
DE            EC=1.3.1.-;
DE   AltName: Full=tRNA-dihydrouridine synthase 3-like;
GN   Name=DUS3L;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
//
ID   DUS3_HUMAN              Reviewed;         185 AA.
AC   P51452; D3DX45; Q5U0J1;
DE   RecName: Full=Dual specificity protein phosphatase 3;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase VHR;
DE   AltName: Full=Vaccinia H1-related phosphatase;
DE            Short=VHR;
GN   Name=DUSP3; Synonyms=VHR;
DR   GO; GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   DUS4L_HUMAN             Reviewed;         317 AA.
AC   O95620; B4DLX0; Q2NKK1;
DE   RecName: Full=tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like;
DE            EC=1.3.1.-;
DE   AltName: Full=pp35;
DE   AltName: Full=tRNA-dihydrouridine synthase 4-like;
GN   Name=DUS4L;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
//
ID   DUS4_HUMAN              Reviewed;         394 AA.
AC   Q13115; B2RBU5; D3DSU4; G5E930; Q13524;
DE   RecName: Full=Dual specificity protein phosphatase 4;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase hVH2;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 2;
DE            Short=MAP kinase phosphatase 2;
DE            Short=MKP-2;
GN   Name=DUSP4; Synonyms=MKP2, VH2;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008330; F:protein tyrosine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0001706; P:endoderm formation; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:ProtInc.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   DUS5_HUMAN              Reviewed;         384 AA.
AC   Q16690; Q12997; Q5T603;
DE   RecName: Full=Dual specificity protein phosphatase 5;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase hVH3;
GN   Name=DUSP5; Synonyms=VH3;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0001706; P:endoderm formation; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS6_HUMAN              Reviewed;         381 AA.
AC   Q16828; O75109; Q53Y75; Q9BSH6;
DE   RecName: Full=Dual specificity protein phosphatase 6;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase PYST1;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 3;
DE            Short=MAP kinase phosphatase 3;
DE            Short=MKP-3;
GN   Name=DUSP6; Synonyms=MKP3, PYST1;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0042663; P:regulation of endodermal cell fate specification; IBA:RefGenome.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0060420; P:regulation of heart growth; IBA:RefGenome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051409; P:response to nitrosative stress; IEP:UniProtKB.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   DUS7_HUMAN              Reviewed;         419 AA.
AC   Q16829; Q2M3J7; Q8NFJ0;
DE   RecName: Full=Dual specificity protein phosphatase 7;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase PYST2;
GN   Name=DUSP7; Synonyms=PYST2;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   DUS8_HUMAN              Reviewed;         625 AA.
AC   Q13202; Q86SS8;
DE   RecName: Full=Dual specificity protein phosphatase 8;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity protein phosphatase hVH-5;
GN   Name=DUSP8; Synonyms=C11orf81, VH5;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IBA:RefGenome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUS9_HUMAN              Reviewed;         384 AA.
AC   Q99956; D3DWU5;
DE   RecName: Full=Dual specificity protein phosphatase 9;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Mitogen-activated protein kinase phosphatase 4;
DE            Short=MAP kinase phosphatase 4;
DE            Short=MKP-4;
GN   Name=DUSP9; Synonyms=MKP4;
DR   GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IBA:RefGenome.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
//
ID   DUSTY_HUMAN             Reviewed;         929 AA.
AC   Q6XUX3; B7ZL64; O75060; Q17R94; Q5RKT0; Q6IN87; Q6P997; Q86Y03;
AC   Q9P1S5;
DE   RecName: Full=Dual serine/threonine and tyrosine protein kinase;
DE            EC=2.7.12.1;
DE   AltName: Full=Dusty protein kinase;
DE            Short=Dusty PK;
DE   AltName: Full=RIP-homologous kinase;
DE   AltName: Full=Receptor-interacting serine/threonine-protein kinase 5;
DE   AltName: Full=Sugen kinase 496;
DE            Short=SgK496;
GN   Name=DSTYK; Synonyms=KIAA0472, RIP5, RIPK5, SGK496; ORFNames=HDCMD38P;
DR   GuidetoPHARMACOLOGY; 2008; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
//
ID   DUTL_HUMAN              Reviewed;         141 AA.
AC   Q6ZN92;
DE   RecName: Full=Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323;
DE            Short=dUTPase-like protein;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0046080; P:dUTP metabolic process; IEA:InterPro.
//
ID   DUT_HUMAN               Reviewed;         252 AA.
AC   P33316; A8K650; B4DPR5; O14785; Q16708; Q16860; Q6FHN1; Q6NSA3;
AC   Q96Q81;
DE   RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial;
DE            Short=dUTPase;
DE            EC=3.6.1.23;
DE   AltName: Full=dUTP pyrophosphatase;
DE   Flags: Precursor;
GN   Name=DUT;
DR   GO; GO:0004170; F:dUTP diphosphatase activity; EXP:Reactome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006226; P:dUMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046080; P:dUTP metabolic process; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   DUX1_HUMAN              Reviewed;         170 AA.
AC   O43812;
DE   RecName: Full=Double homeobox protein 1;
GN   Name=DUX1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   DUX4C_HUMAN             Reviewed;         374 AA.
AC   Q6RFH8;
DE   RecName: Full=Double homeobox protein 4C;
DE   AltName: Full=Double homeobox protein 4, centromeric;
DE            Short=DUX4c;
DE   AltName: Full=Double homeobox protein 4-like protein 9;
GN   Name=DUX4L9; Synonyms=DUX4C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DUX2_HUMAN              Reviewed;          80 AA.
AC   O75505;
DE   RecName: Full=Putative double homeobox protein 2;
GN   Name=DUX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   DUX3_HUMAN              Reviewed;         197 AA.
AC   Q96PT4; Q9UND2;
DE   RecName: Full=Putative double homeobox protein 3;
GN   Name=DUX3;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
//
ID   DUX5_HUMAN              Reviewed;         197 AA.
AC   Q96PT3;
DE   RecName: Full=Double homeobox protein 5;
GN   Name=DUX5;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
//
ID   DUXA_HUMAN              Reviewed;         204 AA.
AC   A6NLW8;
DE   RecName: Full=Double homeobox protein A;
GN   Name=DUXA;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DUX4_HUMAN              Reviewed;         424 AA.
AC   Q9UBX2;
DE   RecName: Full=Double homeobox protein 4;
DE   AltName: Full=Double homeobox protein 10;
DE   AltName: Full=Double homeobox protein 4/10;
GN   Name=DUX4; Synonyms=DUX10;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   DVL1_HUMAN              Reviewed;         695 AA.
AC   O14640; Q5TA33; Q5TA35;
DE   RecName: Full=Segment polarity protein dishevelled homolog DVL-1;
DE            Short=Dishevelled-1;
DE   AltName: Full=DSH homolog 1;
GN   Name=DVL1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0048365; F:Rac GTPase binding; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0048675; P:axon extension; IBA:RefGenome.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090103; P:cochlea morphogenesis; IBA:RefGenome.
DR   GO; GO:0048668; P:collateral sprouting; IBA:RefGenome.
DR   GO; GO:0060026; P:convergent extension; IBA:RefGenome.
DR   GO; GO:0022007; P:convergent extension involved in neural plate elongation; IEA:Ensembl.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0021915; P:neural tube development; IEP:BHF-UCL.
DR   GO; GO:0007528; P:neuromuscular junction development; ISS:BHF-UCL.
DR   GO; GO:0007269; P:neurotransmitter secretion; ISS:BHF-UCL.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IBA:RefGenome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
DR   GO; GO:0035372; P:protein localization to microtubule; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IMP:BHF-UCL.
DR   GO; GO:0043113; P:receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0001505; P:regulation of neurotransmitter levels; ISS:BHF-UCL.
DR   GO; GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; IBA:RefGenome.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; ISS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IDA:BHF-UCL.
//
ID   DVL2_HUMAN              Reviewed;         736 AA.
AC   O14641; D3DTN3; Q53XM0;
DE   RecName: Full=Segment polarity protein dishevelled homolog DVL-2;
DE            Short=Dishevelled-2;
DE   AltName: Full=DSH homolog 2;
GN   Name=DVL2;
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0044340; P:canonical Wnt signaling pathway involved in regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0021535; P:cell migration in hindbrain; IBA:RefGenome.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IBA:RefGenome.
DR   GO; GO:0060026; P:convergent extension; IBA:RefGenome.
DR   GO; GO:0022007; P:convergent extension involved in neural plate elongation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; IBA:RefGenome.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0001843; P:neural tube closure; ISS:BHF-UCL.
DR   GO; GO:0035567; P:non-canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IBA:RefGenome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007379; P:segment specification; ISS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IGI:MGI.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IDA:BHF-UCL.
//
ID   DVL3_HUMAN              Reviewed;         716 AA.
AC   Q92997; B4E3E5; D3DNT0; O14642; Q13531; Q8N5E9; Q92607;
DE   RecName: Full=Segment polarity protein dishevelled homolog DVL-3;
DE            Short=Dishevelled-3;
DE   AltName: Full=DSH homolog 3;
GN   Name=DVL3; Synonyms=KIAA0208;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090103; P:cochlea morphogenesis; IBA:RefGenome.
DR   GO; GO:0060026; P:convergent extension; IBA:RefGenome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0035567; P:non-canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0038031; P:non-canonical Wnt signaling pathway via JNK cascade; ISS:BHF-UCL.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; IBA:RefGenome.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IBA:RefGenome.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IDA:BHF-UCL.
//
ID   DVLP1_HUMAN             Reviewed;         670 AA.
AC   P54792;
DE   RecName: Full=Putative segment polarity protein dishevelled homolog DVL1P1;
DE   AltName: Full=DSH homolog 1-like;
DE   AltName: Full=Segment polarity protein dishevelled homolog DVL-1-like;
DE            Short=Dishevelled-1-like;
GN   Name=DVL1P1; Synonyms=DVL, DVL1, DVL1L1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; NAS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   DX26B_HUMAN             Reviewed;         861 AA.
AC   Q5JSJ4; Q5CZA2; Q6IPS3; Q6ZTU5; Q6ZWE4;
DE   RecName: Full=Protein DDX26B;
GN   Name=DDX26B;
//
ID   DX39A_HUMAN             Reviewed;         427 AA.
AC   O00148; Q8N5M0; Q9BVP6; Q9H5W0;
DE   RecName: Full=ATP-dependent RNA helicase DDX39A;
DE            EC=3.6.4.13;
DE   AltName: Full=DEAD box protein 39;
DE   AltName: Full=Nuclear RNA helicase URH49;
GN   Name=DDX39A; Synonyms=DDX39;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IGI:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IGI:UniProtKB.
//
ID   DX39B_HUMAN             Reviewed;         428 AA.
AC   Q13838; B0S8C0; O43496; Q0EFA1; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66;
AC   Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6;
AC   Q5STU8; Q71V76;
DE   RecName: Full=Spliceosome RNA helicase DDX39B;
DE            EC=3.6.4.13;
DE   AltName: Full=56 kDa U2AF65-associated protein;
DE   AltName: Full=ATP-dependent RNA helicase p47;
DE   AltName: Full=DEAD box protein UAP56;
DE   AltName: Full=HLA-B-associated transcript 1 protein;
GN   Name=DDX39B; Synonyms=BAT1, UAP56;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043008; F:ATP-dependent protein binding; IDA:BHF-UCL.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008186; F:RNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0030621; F:U4 snRNA binding; IDA:BHF-UCL.
DR   GO; GO:0017070; F:U6 snRNA binding; IDA:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IGI:UniProtKB.
DR   GO; GO:2000002; P:negative regulation of DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IMP:UniProtKB.
DR   GO; GO:0010501; P:RNA secondary structure unwinding; IDA:BHF-UCL.
DR   GO; GO:0008380; P:RNA splicing; IDA:BHF-UCL.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IDA:BHF-UCL.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   DXO_HUMAN               Reviewed;         396 AA.
AC   O77932; A2CER3; B0UZ80; O15004; O78127; O78128; Q5ST60; Q6IPZ2;
AC   Q9NPK4;
DE   RecName: Full=Decapping and exoribonuclease protein;
DE            Short=DXO;
DE            EC=3.1.13.-;
DE            EC=3.6.1.-;
DE   AltName: Full=Dom-3 homolog Z;
GN   Name=DXO; Synonyms=DOM3L, DOM3Z, NG6;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0034353; F:RNA pyrophosphohydrolase activity; ISS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; ISS:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.
DR   GO; GO:0071028; P:nuclear mRNA surveillance; ISS:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; ISS:UniProtKB.
DR   GO; GO:0050779; P:RNA destabilization; ISS:UniProtKB.
//
ID   DYDC1_HUMAN             Reviewed;         177 AA.
AC   Q8WWB3; Q5QP03; Q5QP04; Q6WNP4; Q6ZU87;
DE   RecName: Full=DPY30 domain-containing protein 1;
GN   Name=DYDC1; Synonyms=DPY30D1; ORFNames=RSD-9, RSD9;
//
ID   DYDC2_HUMAN             Reviewed;         177 AA.
AC   Q96IM9; D3DWD6; Q5QP07; Q5QP11;
DE   RecName: Full=DPY30 domain-containing protein 2;
GN   Name=DYDC2;
//
ID   DYH10_HUMAN             Reviewed;        4471 AA.
AC   Q8IVF4; C9JMF5; O95495; Q6ZUC9; Q6ZUP6; Q8N761;
DE   RecName: Full=Dynein heavy chain 10, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 10;
DE   AltName: Full=Ciliary dynein heavy chain 10;
GN   Name=DNAH10; Synonyms=KIAA2017;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH11_HUMAN             Reviewed;        4523 AA.
AC   Q96DT5; Q9UJ82;
DE   RecName: Full=Dynein heavy chain 11, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 11;
DE   AltName: Full=Ciliary dynein heavy chain 11;
GN   Name=DNAH11;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:Ensembl.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH12_HUMAN             Reviewed;        3092 AA.
AC   Q6ZR08; A6NGI2; Q6ZTR8; Q8N7R9; Q8WXK2; Q92816;
DE   RecName: Full=Dynein heavy chain 12, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 12;
DE   AltName: Full=Axonemal dynein heavy chain 12-like protein;
DE   AltName: Full=Axonemal dynein heavy chain 7-like protein;
DE   AltName: Full=Ciliary dynein heavy chain 12;
DE   AltName: Full=Dynein heavy chain 7-like, axonemal;
DE   AltName: Full=Dynein heavy chain domain-containing protein 2;
GN   Name=DNAH12;
GN   Synonyms=DHC3, DLP12, DNAH12L, DNAH7L, DNAHC3, DNHD2, HDHC3, HL19;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH14_HUMAN             Reviewed;        3507 AA.
AC   Q0VDD8; A6NG62; A6NNL2; Q0VDD9; Q4VXC7; Q4VXG4; Q4VXG5; Q5VU33;
AC   Q5VU34;
DE   RecName: Full=Dynein heavy chain 14, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 14;
DE   AltName: Full=Ciliary dynein heavy chain 14;
GN   Name=DNAH14; Synonyms=C1orf67;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH17_HUMAN             Reviewed;        4485 AA.
AC   Q9UFH2; O00431; O15206; Q2M2Y1; Q6ZRQ2; Q8N7Q7;
DE   RecName: Full=Dynein heavy chain 17, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 17;
DE   AltName: Full=Axonemal dynein heavy chain-like protein 1;
DE   AltName: Full=Ciliary dynein heavy chain 17;
DE   AltName: Full=Ciliary dynein heavy chain-like protein 1;
DE   AltName: Full=Dynein light chain 2, axonemal;
GN   Name=DNAH17; Synonyms=DNAHL1, DNEL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH1_HUMAN              Reviewed;        4330 AA.
AC   Q9P2D7; B0I1R6; O00436; O15435; O95491; Q6ZU48; Q86YK7; Q8TEJ4;
AC   Q92863; Q9H8E6; Q9UFW6; Q9Y4Z7;
DE   RecName: Full=Dynein heavy chain 1, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 1;
DE   AltName: Full=Ciliary dynein heavy chain 1;
DE   AltName: Full=Heat shock regulated protein 1;
DE            Short=HSRF-1;
DE   AltName: Full=hDHC7;
GN   Name=DNAH1; Synonyms=DHC7, DNAHC1, KIAA1410;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; NAS:UniProtKB.
//
ID   DYH2_HUMAN              Reviewed;        4427 AA.
AC   Q9P225; A8K992; B5MDX5; O15434; Q6PIH3; Q6ZR42;
DE   RecName: Full=Dynein heavy chain 2, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 2;
DE   AltName: Full=Ciliary dynein heavy chain 2;
DE   AltName: Full=Dynein heavy chain domain-containing protein 3;
GN   Name=DNAH2; Synonyms=DNAHC2, DNHD3, KIAA1503;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH3_HUMAN              Reviewed;        4116 AA.
AC   Q8TD57; O00437; O15437; O43326; Q3C0H2; Q8WUP9; Q9UEM3; Q9UEM5;
AC   Q9UG35;
DE   RecName: Full=Dynein heavy chain 3, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 3;
DE            Short=HsADHC3;
DE   AltName: Full=Ciliary dynein heavy chain 3;
DE   AltName: Full=Dnahc3-b;
GN   Name=DNAH3; Synonyms=DNAHC3B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH5_HUMAN              Reviewed;        4624 AA.
AC   Q8TE73; Q92860; Q96L74; Q9H5S7; Q9HCG9;
DE   RecName: Full=Dynein heavy chain 5, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 5;
DE   AltName: Full=Ciliary dynein heavy chain 5;
GN   Name=DNAH5; Synonyms=DNAHC5, HL1, KIAA1603;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH6_HUMAN              Reviewed;        4158 AA.
AC   Q9C0G6; A0PJN9; B5MEE0; B7ZL99; O95493; Q53QZ1; Q53TE5; Q8N1W6;
AC   Q92861; Q96BL6; Q9H030; Q9H5E1;
DE   RecName: Full=Dynein heavy chain 6, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 6;
DE   AltName: Full=Ciliary dynein heavy chain 6;
GN   Name=DNAH6; Synonyms=DNAHC6, DNHL1, HL2, KIAA1697;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH7_HUMAN              Reviewed;        4024 AA.
AC   Q8WXX0; B8ZZX8; O00433; O95492; Q4G152; Q53QX7; Q53S64; Q53T02;
AC   Q68CY5; Q8N1Z2; Q9UMS3; Q9Y2F3;
DE   RecName: Full=Dynein heavy chain 7, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 7;
DE   AltName: Full=Ciliary dynein heavy chain 7;
DE   AltName: Full=Dynein heavy chain-like protein 2;
DE   AltName: Full=hDHC2;
GN   Name=DNAH7; Synonyms=KIAA0944;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH8_HUMAN              Reviewed;        4490 AA.
AC   Q96JB1; O00438; Q5JYI2; Q5T2M3; Q5T2M4; Q5TG00; Q9UEM4;
DE   RecName: Full=Dynein heavy chain 8, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 8;
DE   AltName: Full=Ciliary dynein heavy chain 8;
GN   Name=DNAH8;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   DYH9_HUMAN              Reviewed;        4486 AA.
AC   Q9NYC9; A2VCQ8; O15064; O95494; Q9NQ28;
DE   RecName: Full=Dynein heavy chain 9, axonemal;
DE   AltName: Full=Axonemal beta dynein heavy chain 9;
DE   AltName: Full=Ciliary dynein heavy chain 9;
GN   Name=DNAH9; Synonyms=DNAH17L, DNAL1, KIAA0357;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   DYHC1_HUMAN             Reviewed;        4646 AA.
AC   Q14204; B0I1R0; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5;
DE   RecName: Full=Cytoplasmic dynein 1 heavy chain 1;
DE   AltName: Full=Cytoplasmic dynein heavy chain 1;
DE   AltName: Full=Dynein heavy chain, cytosolic;
GN   Name=DYNC1H1; Synonyms=DHC1, DNCH1, DNCL, DNECL, DYHC, KIAA0325;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; ISS:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007052; P:mitotic spindle organization; NAS:UniProtKB.
DR   GO; GO:0034063; P:stress granule assembly; ISS:BHF-UCL.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DYHC2_HUMAN             Reviewed;        4307 AA.
AC   Q8NCM8; O00432; Q16693; Q3C1U8; Q4AC93; Q6ZMX7; Q6ZUM6; Q7Z363;
AC   Q8N977; Q92815; Q9HAE4;
DE   RecName: Full=Cytoplasmic dynein 2 heavy chain 1;
DE   AltName: Full=Cytoplasmic dynein 2 heavy chain;
DE   AltName: Full=Dynein cytoplasmic heavy chain 2;
DE   AltName: Full=Dynein heavy chain 11;
DE            Short=hDHC11;
DE   AltName: Full=Dynein heavy chain isotype 1B;
GN   Name=DYNC2H1; Synonyms=DHC1B, DHC2, DNCH2, DYH1B, KIAA1997;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008105; P:asymmetric protein localization; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:InterPro.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007030; P:Golgi organization; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
//
ID   DYL1_HUMAN              Reviewed;          89 AA.
AC   P63167; Q15701;
DE   RecName: Full=Dynein light chain 1, cytoplasmic;
DE   AltName: Full=8 kDa dynein light chain;
DE            Short=DLC8;
DE   AltName: Full=Dynein light chain LC8-type 1;
DE   AltName: Full=Protein inhibitor of neuronal nitric oxide synthase;
DE            Short=PIN;
GN   Name=DYNLL1; Synonyms=DLC1, DNCL1, DNCLC1, HDLC1;
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0030235; F:nitric-oxide synthase regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   DYL2_HUMAN              Reviewed;          89 AA.
AC   Q96FJ2; B2R5B4;
DE   RecName: Full=Dynein light chain 2, cytoplasmic;
DE   AltName: Full=8 kDa dynein light chain b;
DE            Short=DLC8b;
DE   AltName: Full=Dynein light chain LC8-type 2;
GN   Name=DYNLL2; Synonyms=DLC2;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0008039; P:synaptic target recognition; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DYLT1_HUMAN             Reviewed;         113 AA.
AC   P63172; Q15763; Q5VTU4;
DE   RecName: Full=Dynein light chain Tctex-type 1;
DE   AltName: Full=Protein CW-1;
DE   AltName: Full=T-complex testis-specific protein 1 homolog;
GN   Name=DYNLT1; Synonyms=TCTEL1, TCTEX-1, TCTEX1;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; ISS:UniProtKB.
DR   GO; GO:0019060; P:intracellular transport of viral protein in host cell; IMP:UniProtKB.
DR   GO; GO:0075521; P:microtubule-dependent intracellular transport of viral material towards nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
//
ID   DYLT3_HUMAN             Reviewed;         116 AA.
AC   P51808; Q6ICS3;
DE   RecName: Full=Dynein light chain Tctex-type 3;
DE   AltName: Full=Protein 91/23;
DE   AltName: Full=T-complex-associated testis-expressed 1-like;
GN   Name=DYNLT3; Synonyms=TCTE1L, TCTE1XL;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   DYM_HUMAN               Reviewed;         669 AA.
AC   Q7RTS9; A8K5I8; B2RCF9; B4DKI7; Q3ZTS8; Q6P2P5; Q8N2M0; Q9BVE9;
AC   Q9NPU7;
DE   RecName: Full=Dymeclin;
DE   AltName: Full=Dyggve-Melchior-Clausen syndrome protein;
GN   Name=DYM;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060348; P:bone development; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
//
ID   DYN1_HUMAN              Reviewed;         864 AA.
AC   Q05193; A6NLM6; Q5SYX0; Q5SYX2; Q6P3T6; Q86VD2;
DE   RecName: Full=Dynamin-1;
DE            EC=3.6.5.5;
GN   Name=DNM1; Synonyms=DNM;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IMP:BHF-UCL.
DR   GO; GO:0007032; P:endosome organization; IMP:BHF-UCL.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0031623; P:receptor internalization; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
//
ID   DYN2_HUMAN              Reviewed;         870 AA.
AC   P50570; A8K1B6; E7EV30; E9PEQ4; K7ESI9; Q5I0Y0; Q7Z5S3; Q9UPH4;
DE   RecName: Full=Dynamin-2;
DE            EC=3.6.5.5;
GN   Name=DNM2; Synonyms=DYN2;
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; NAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0031623; P:receptor internalization; IMP:BHF-UCL.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048489; P:synaptic vesicle transport; NAS:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; IMP:BHF-UCL.
//
ID   DYNAP_HUMAN             Reviewed;         210 AA.
AC   Q8N1N2;
DE   RecName: Full=Dynactin-associated protein;
DE            Short=Full;
GN   Name=DYNAP; Synonyms=C18orf26;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:UniProtKB.
DR   GO; GO:1901625; P:cellular response to ergosterol; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
//
ID   DYN3_HUMAN              Reviewed;         869 AA.
AC   Q9UQ16; A9Z1Y1; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3;
AC   Q9H548; Q9NQ68; Q9NQN6;
DE   RecName: Full=Dynamin-3;
DE            EC=3.6.5.5;
DE   AltName: Full=Dynamin, testicular;
DE   AltName: Full=T-dynamin;
GN   Name=DNM3; Synonyms=KIAA0820;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; ISS:GOC.
DR   GO; GO:0007416; P:synapse assembly; ISS:UniProtKB.
//
ID   DYR1A_HUMAN             Reviewed;         763 AA.
AC   Q13627; O60769; Q92582; Q92810; Q9UNM5;
DE   RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 1A;
DE            EC=2.7.12.1;
DE   AltName: Full=Dual specificity YAK1-related kinase;
DE   AltName: Full=HP86;
DE   AltName: Full=Protein kinase minibrain homolog;
DE            Short=MNBH;
DE            Short=hMNB;
GN   Name=DYRK1A; Synonyms=DYRK, MNB, MNBH;
DR   GuidetoPHARMACOLOGY; 2009; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0043621; F:protein self-association; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0048156; F:tau protein binding; ISS:BHF-UCL.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0090312; P:positive regulation of protein deacetylation; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
//
ID   DYR1B_HUMAN             Reviewed;         629 AA.
AC   Q9Y463; O75258; O75788; O75789;
DE   RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 1B;
DE            EC=2.7.12.1;
DE   AltName: Full=Minibrain-related kinase;
DE   AltName: Full=Mirk protein kinase;
GN   Name=DYRK1B; Synonyms=MIRK;
DR   GuidetoPHARMACOLOGY; 2010; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   DYRK2_HUMAN             Reviewed;         601 AA.
AC   Q92630; B2R9V9; Q9BRB5;
DE   RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 2;
DE            EC=2.7.12.1;
GN   Name=DYRK2;
DR   GuidetoPHARMACOLOGY; 2011; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB.
//
ID   DYRK3_HUMAN             Reviewed;         588 AA.
AC   O43781; D3DT79; Q7Z752; Q9HBY6; Q9HBY7;
DE   RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 3;
DE            EC=2.7.12.1;
DE   AltName: Full=Regulatory erythroid kinase;
DE            Short=REDK;
GN   Name=DYRK3;
DR   GuidetoPHARMACOLOGY; 2012; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030218; P:erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   DYRK4_HUMAN             Reviewed;         520 AA.
AC   Q9NR20; Q8NEF2; Q92631;
DE   RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 4;
DE            EC=2.7.12.1;
GN   Name=DYRK4;
DR   GuidetoPHARMACOLOGY; 2013; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
//
ID   DYRL1_HUMAN             Reviewed;         187 AA.
AC   Q86XF0; D3DN30; Q6P4I9;
DE   RecName: Full=Dihydrofolate reductase, mitochondrial;
DE            EC=1.5.1.3;
DE   AltName: Full=Dihydrofolate reductase-like protein 1;
GN   Name=DHFRL1; Synonyms=DHFRP4;
DR   GO; GO:0004146; F:dihydrofolate reductase activity; IMP:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0006545; P:glycine biosynthetic process; IEA:InterPro.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IDA:UniProtKB.
DR   GO; GO:0046105; P:thymidine biosynthetic process; IDA:UniProtKB.
//
ID   DYR_HUMAN               Reviewed;         187 AA.
AC   P00374; Q14130; Q6IRW8;
DE   RecName: Full=Dihydrofolate reductase;
DE            EC=1.5.1.3;
GN   Name=DHFR;
DR   GuidetoPHARMACOLOGY; 2603; -.
DR   GO; GO:0004146; F:dihydrofolate reductase activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006545; P:glycine biosynthetic process; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031427; P:response to methotrexate; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   DYSF_HUMAN              Reviewed;        2080 AA.
AC   O75923; A0FK00; B1PZ70; B1PZ71; B1PZ72; B1PZ73; B1PZ74; B1PZ75;
AC   B1PZ76; B1PZ77; B1PZ78; B1PZ79; B1PZ80; B1PZ81; B3KQB9; O75696;
AC   Q09EX5; Q0H395; Q53QY3; Q53TD2; Q8TEL8; Q9UEN7;
DE   RecName: Full=Dysferlin;
DE   AltName: Full=Dystrophy-associated fer-1-like protein;
DE   AltName: Full=Fer-1-like protein 1;
GN   Name=DYSF; Synonyms=FER1L1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IMP:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR   GO; GO:0006906; P:vesicle fusion; IEA:Ensembl.
//
ID   DYST_HUMAN              Reviewed;        7570 AA.
AC   Q03001; B7Z3H1; O94833; Q12825; Q13266; Q13267; Q13775; Q5TBT0;
AC   Q5TBT2; Q5TF23; Q5TF24; Q8N1T8; Q8N8J3; Q8WXK8; Q8WXK9; Q96AK9;
AC   Q96DQ5; Q96J76; Q96QT5; Q9H555; Q9UGD7; Q9UGD8; Q9UN10;
DE   RecName: Full=Dystonin;
DE   AltName: Full=230 kDa bullous pemphigoid antigen;
DE   AltName: Full=230/240 kDa bullous pemphigoid antigen;
DE   AltName: Full=Bullous pemphigoid antigen 1;
DE            Short=BPA;
DE            Short=Bullous pemphigoid antigen;
DE   AltName: Full=Dystonia musculorum protein;
DE   AltName: Full=Hemidesmosomal plaque protein;
GN   Name=DST; Synonyms=BP230, BP240, BPAG1, DMH, DT, KIAA0728;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
DR   GO; GO:0048870; P:cell motility; IMP:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEP:UniProtKB.
DR   GO; GO:0030011; P:maintenance of cell polarity; IMP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IDA:UniProtKB.
DR   GO; GO:0008090; P:retrograde axon cargo transport; IEA:Ensembl.
//
ID   DYTN_HUMAN              Reviewed;         578 AA.
AC   A2CJ06;
DE   RecName: Full=Dystrotelin;
GN   Name=DYTN;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   DYXC1_HUMAN             Reviewed;         420 AA.
AC   Q8WXU2; Q6P5Y9; Q8N1S6;
DE   RecName: Full=Dyslexia susceptibility 1 candidate gene 1 protein;
GN   Name=DYX1C1; Synonyms=EKN1;
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003341; P:cilium movement; IMP:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
DR   GO; GO:0036159; P:inner dynein arm assembly; IMP:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0036158; P:outer dynein arm assembly; IMP:UniProtKB.
DR   GO; GO:0033146; P:regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.
//
ID   DZAN1_HUMAN             Reviewed;         752 AA.
AC   Q9NVP4; B7ZLZ4; Q4F7X1; Q5QPD9; Q5QPE0; Q68DN8; Q6ZMX9; Q96NF0;
AC   Q9H1E0; Q9H442;
DE   RecName: Full=Double zinc ribbon and ankyrin repeat-containing protein 1;
GN   Name=DZANK1; Synonyms=C20orf12, C20orf84;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   DZI1L_HUMAN             Reviewed;         767 AA.
AC   Q8IYY4; C9JUG5; Q96M38;
DE   RecName: Full=Zinc finger protein DZIP1L;
DE   AltName: Full=DAZ-interacting protein 1-like protein;
GN   Name=DZIP1L;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042384; P:cilium assembly; IMP:BHF-UCL.
//
ID   DZIP1_HUMAN             Reviewed;         867 AA.
AC   Q86YF9; Q5W078; Q5W079; Q8WY45; Q8WY46; Q9UGA5; Q9Y2K0;
DE   RecName: Full=Zinc finger protein DZIP1;
DE   AltName: Full=DAZ-interacting protein 1/2;
GN   Name=DZIP1; Synonyms=DZIP, DZIP2, KIAA0996;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0007281; P:germ cell development; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   DZIP3_HUMAN             Reviewed;        1208 AA.
AC   Q86Y13; B3KN01; O75162; Q6P3R9; Q6PH82; Q86Y14; Q86Y15; Q86Y16;
AC   Q8IWI0; Q96RS9;
DE   RecName: Full=E3 ubiquitin-protein ligase DZIP3;
DE            EC=6.3.2.-;
DE   AltName: Full=DAZ-interacting protein 3;
DE   AltName: Full=RNA-binding ubiquitin ligase of 138 kDa;
DE            Short=hRUL138;
GN   Name=DZIP3; Synonyms=KIAA0675;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
//
ID   E2AK1_HUMAN             Reviewed;         630 AA.
AC   Q9BQI3; A8K2R2; Q549K6; Q8NBW3; Q9HC02; Q9NYE0; Q9P0V6; Q9P1J5;
AC   Q9P2H8; Q9UHG4;
DE   RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Heme-controlled repressor;
DE            Short=HCR;
DE   AltName: Full=Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase;
DE   AltName: Full=Heme-regulated inhibitor;
DE   AltName: Full=Hemin-sensitive initiation factor 2-alpha kinase;
GN   Name=EIF2AK1; Synonyms=HRI, KIAA1369; ORFNames=PRO1362;
DR   GuidetoPHARMACOLOGY; 2015; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0046986; P:negative regulation of hemoglobin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0045993; P:negative regulation of translational initiation by iron; NAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0046501; P:protoporphyrinogen IX metabolic process; IEA:Ensembl.
DR   GO; GO:0010999; P:regulation of eIF2 alpha phosphorylation by heme; IEA:Ensembl.
DR   GO; GO:0009605; P:response to external stimulus; IEP:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IEP:UniProtKB.
//
ID   E2AK2_HUMAN             Reviewed;         551 AA.
AC   P19525; A8K3P0; D6W584; E9PC80; Q52M43; Q7Z6F6; Q9UIR4;
DE   RecName: Full=Interferon-induced, double-stranded RNA-activated protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 2;
DE            Short=eIF-2A protein kinase 2;
DE   AltName: Full=Interferon-inducible RNA-dependent protein kinase;
DE   AltName: Full=P1/eIF-2A protein kinase;
DE   AltName: Full=Protein kinase RNA-activated;
DE            Short=PKR;
DE   AltName: Full=Tyrosine-protein kinase EIF2AK2;
DE            EC=2.7.10.2;
DE   AltName: Full=p68 kinase;
GN   Name=EIF2AK2; Synonyms=PKR, PRKR;
DR   GuidetoPHARMACOLOGY; 2016; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; TAS:ProtInc.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0000186; P:activation of MAPKK activity; IMP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0030683; P:evasion or tolerance by virus of host immune response; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:Reactome.
DR   GO; GO:0019054; P:modulation by virus of host process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IMP:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0032722; P:positive regulation of chemokine production; ISS:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:1901224; P:positive regulation of NIK/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:1901532; P:regulation of hematopoietic progenitor cell differentiation; ISS:UniProtKB.
DR   GO; GO:1902036; P:regulation of hematopoietic stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:1902033; P:regulation of hematopoietic stem cell proliferation; ISS:UniProtKB.
DR   GO; GO:1900225; P:regulation of NLRP3 inflammasome complex assembly; ISS:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; IEA:Ensembl.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
//
ID   E2AK3_HUMAN             Reviewed;        1116 AA.
AC   Q9NZJ5; A0AVH1; A0AVH2; B2RCU9; O95846; Q53QY0; Q53SB1;
DE   RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=PRKR-like endoplasmic reticulum kinase;
DE   AltName: Full=Pancreatic eIF2-alpha kinase;
DE            Short=HsPEK;
DE   Flags: Precursor;
GN   Name=EIF2AK3; Synonyms=PEK, PERK;
DR   GuidetoPHARMACOLOGY; 2017; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0030282; P:bone mineralization; ISS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0002063; P:chondrocyte development; ISS:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; IMP:UniProtKB.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; ISS:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0006983; P:ER overload response; IDA:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; ISS:UniProtKB.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0031642; P:negative regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; TAS:UniProtKB.
DR   GO; GO:0032057; P:negative regulation of translational initiation in response to stress; TAS:UniProtKB.
DR   GO; GO:0001503; P:ossification; IMP:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; ISS:UniProtKB.
DR   GO; GO:0032933; P:SREBP signaling pathway; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; IEA:Ensembl.
//
ID   E2AK4_HUMAN             Reviewed;        1649 AA.
AC   Q9P2K8; C9JEC4; Q69YL7; Q6DC97; Q96GN6; Q9H5K1; Q9NSQ3; Q9NSZ5;
AC   Q9UJ56;
DE   RecName: Full=Eukaryotic translation initiation factor 2-alpha kinase 4;
DE            EC=2.7.11.1;
DE   AltName: Full=GCN2-like protein;
GN   Name=EIF2AK4; Synonyms=GCN2, KIAA1338;
DR   GuidetoPHARMACOLOGY; 2018; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004694; F:eukaryotic translation initiation factor 2alpha kinase activity; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006446; P:regulation of translational initiation; ISS:UniProtKB.
DR   GO; GO:0043558; P:regulation of translational initiation in response to stress; IEA:Ensembl.
//
ID   E2F1_HUMAN              Reviewed;         437 AA.
AC   Q01094; Q13143; Q92768;
DE   RecName: Full=Transcription factor E2F1;
DE            Short=E2F-1;
DE   AltName: Full=PBR3;
DE   AltName: Full=Retinoblastoma-associated protein 1;
DE            Short=RBAP-1;
DE   AltName: Full=Retinoblastoma-binding protein 3;
DE            Short=RBBP-3;
DE   AltName: Full=pRB-binding protein E2F-1;
GN   Name=E2F1; Synonyms=RBBP3;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0043276; P:anoikis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:UniProtKB.
DR   GO; GO:1990086; P:lens fiber cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000080; P:mitotic G1 phase; TAS:ProtInc.
DR   GO; GO:0000085; P:mitotic G2 phase; TAS:Reactome.
DR   GO; GO:0048255; P:mRNA stabilization; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0071930; P:negative regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   E2F2_HUMAN              Reviewed;         437 AA.
AC   Q14209; B2R9W1; Q7Z6H1;
DE   RecName: Full=Transcription factor E2F2;
DE            Short=E2F-2;
GN   Name=E2F2;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:1990086; P:lens fiber cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.
//
ID   E2F3_HUMAN              Reviewed;         465 AA.
AC   O00716; Q15000; Q68DT0; Q9BZ44;
DE   RecName: Full=Transcription factor E2F3;
DE            Short=E2F-3;
GN   Name=E2F3; Synonyms=KIAA0075;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000085; P:mitotic G2 phase; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.
//
ID   E2F4_HUMAN              Reviewed;         413 AA.
AC   Q16254; A6NGR8; B5BU56; Q12991; Q15328;
DE   RecName: Full=Transcription factor E2F4;
DE            Short=E2F-4;
GN   Name=E2F4;
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0008015; P:blood circulation; IEA:Ensembl.
DR   GO; GO:0006884; P:cell volume homeostasis; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0002064; P:epithelial cell development; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   E2F5_HUMAN              Reviewed;         346 AA.
AC   Q15329; E9PBN9; Q16601; Q92756;
DE   RecName: Full=Transcription factor E2F5;
DE            Short=E2F-5;
GN   Name=E2F5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   E2F6_HUMAN              Reviewed;         281 AA.
AC   O75461; A8K2Z8; G5E936; O60544; Q53QY9; Q6Q9Z6; Q7Z2H6;
DE   RecName: Full=Transcription factor E2F6;
DE            Short=E2F-6;
GN   Name=E2F6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   E2F7_HUMAN              Reviewed;         911 AA.
AC   Q96AV8; A6NC74; B2RMR7; B3KTZ5; B3KUP8; B5MED9;
DE   RecName: Full=Transcription factor E2F7;
DE            Short=E2F-7;
GN   Name=E2F7;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0060718; P:chorionic trophoblast cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0070365; P:hepatocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0032466; P:negative regulation of cytokinesis; ISS:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0071930; P:negative regulation of transcription involved in G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0001890; P:placenta development; ISS:UniProtKB.
DR   GO; GO:0032877; P:positive regulation of DNA endoreduplication; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
//
ID   E2F8_HUMAN              Reviewed;         867 AA.
AC   A0AVK6; A8K9H3; Q2VPJ3; Q3C1U6; Q5BKY4; Q8N340; Q9H5M0;
DE   RecName: Full=Transcription factor E2F8;
DE            Short=E2F-8;
GN   Name=E2F8;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0033301; P:cell cycle comprising mitosis without cytokinesis; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0060718; P:chorionic trophoblast cell differentiation; ISS:UniProtKB.
DR   GO; GO:0070365; P:hepatocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0032466; P:negative regulation of cytokinesis; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0001890; P:placenta development; ISS:UniProtKB.
DR   GO; GO:0032877; P:positive regulation of DNA endoreduplication; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
//
ID   E400N_HUMAN             Reviewed;         488 AA.
AC   Q6ZTU2; A6NLB7; A8K0Z5; B3KQY2; Q6NXP1; Q8N253; Q8N7S7; Q9UFJ3;
DE   RecName: Full=EP400 N-terminal-like protein;
GN   Name=EP400NL;
//
ID   E41L1_HUMAN             Reviewed;         881 AA.
AC   Q9H4G0; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7;
AC   Q96CV5; Q96L65;
DE   RecName: Full=Band 4.1-like protein 1;
DE   AltName: Full=Neuronal protein 4.1;
DE            Short=4.1N;
GN   Name=EPB41L1; Synonyms=KIAA0338;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   E41L2_HUMAN             Reviewed;        1005 AA.
AC   O43491; B4DHI8; E9PPD9; Q5T4F0; Q68DV2;
DE   RecName: Full=Band 4.1-like protein 2;
DE   AltName: Full=Generally expressed protein 4.1;
DE            Short=4.1G;
GN   Name=EPB41L2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
//
ID   E41L3_HUMAN             Reviewed;        1087 AA.
AC   Q9Y2J2; B7Z4I5; F5GX05; O95713; Q9BRP5;
DE   RecName: Full=Band 4.1-like protein 3;
DE   AltName: Full=4.1B;
DE   AltName: Full=Differentially expressed in adenocarcinoma of the lung protein 1;
DE            Short=DAL-1;
DE   Contains:
DE     RecName: Full=Band 4.1-like protein 3, N-terminally processed;
GN   Name=EPB41L3; Synonyms=DAL1, KIAA0987;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0030865; P:cortical cytoskeleton organization; TAS:BHF-UCL.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:BHF-UCL.
DR   GO; GO:0043217; P:myelin maintenance; ISS:BHF-UCL.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030913; P:paranodal junction assembly; ISS:BHF-UCL.
DR   GO; GO:0071205; P:protein localization to juxtaparanode region of axon; ISS:BHF-UCL.
DR   GO; GO:0002175; P:protein localization to paranode region of axon; ISS:BHF-UCL.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:BHF-UCL.
//
ID   E41L5_HUMAN             Reviewed;         733 AA.
AC   Q9HCM4; Q7Z5S1; Q8IZ12; Q9H975;
DE   RecName: Full=Band 4.1-like protein 5;
GN   Name=EPB41L5; Synonyms=KIAA1548;
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:Ensembl.
DR   GO; GO:0003383; P:apical constriction; IEA:Ensembl.
DR   GO; GO:0048319; P:axial mesoderm morphogenesis; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
DR   GO; GO:0007509; P:mesoderm migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0001839; P:neural plate morphogenesis; IEA:Ensembl.
DR   GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0010608; P:posttranscriptional regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0070201; P:regulation of establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
DR   GO; GO:0006931; P:substrate-dependent cell migration, cell attachment to substrate; IEA:Ensembl.
DR   GO; GO:0009826; P:unidimensional cell growth; IEA:Ensembl.
//
ID   E41LA_HUMAN             Reviewed;         686 AA.
AC   Q9HCS5; A4FUI6;
DE   RecName: Full=Band 4.1-like protein 4A;
DE   AltName: Full=Protein NBL4;
GN   Name=EPB41L4A; Synonyms=EPB41L4;
//
ID   E41LB_HUMAN             Reviewed;         900 AA.
AC   Q9H329; Q5T4G5; Q5T4G6; Q9H328; Q9P2V3;
DE   RecName: Full=Band 4.1-like protein 4B;
DE   AltName: Full=FERM-containing protein CG1;
DE   AltName: Full=Protein EHM2;
GN   Name=EPB41L4B; Synonyms=EHM2;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0031032; P:actomyosin structure organization; IDA:MGI.
//
ID   E4F1_HUMAN              Reviewed;         784 AA.
AC   Q66K89; A8K2R4; O00146;
DE   RecName: Full=Transcription factor E4F1;
DE            EC=6.3.2.-;
DE   AltName: Full=E4F transcription factor 1;
DE   AltName: Full=Putative E3 ubiquitin-protein ligase E4F1;
DE   AltName: Full=Transcription factor E4F;
DE   AltName: Full=p120E4F;
DE   AltName: Full=p50E4F;
GN   Name=E4F1; Synonyms=E4F;
DR   GO; GO:0035497; F:cAMP response element binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0010564; P:regulation of cell cycle process; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0009794; P:regulation of mitotic cell cycle, embryonic; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   EA3L2_HUMAN             Reviewed;         546 AA.
AC   A6NLF2;
DE   RecName: Full=RNA polymerase II transcription factor SIII subunit A3-like-2;
DE   AltName: Full=Elongin-A3-like-2;
DE            Short=EloA3-like-2;
DE   AltName: Full=Transcription elongation factor B polypeptide 3C-like-2;
GN   Name=TCEB3CL2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EA3L1_HUMAN             Reviewed;         546 AA.
AC   Q3SY89; Q3MI93;
DE   RecName: Full=RNA polymerase II transcription factor SIII subunit A3-like-1;
DE   AltName: Full=Elongin-A3-like-1;
DE            Short=EloA3-like-1;
DE   AltName: Full=Transcription elongation factor B polypeptide 3C-like-1;
GN   Name=TCEB3CL;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EAA1_HUMAN              Reviewed;         542 AA.
AC   P43003; B2R5T3; Q4JCQ8;
DE   RecName: Full=Excitatory amino acid transporter 1;
DE   AltName: Full=Sodium-dependent glutamate/aspartate transporter 1;
DE            Short=GLAST-1;
DE   AltName: Full=Solute carrier family 1 member 3;
GN   Name=SLC1A3; Synonyms=EAAT1, GLAST, GLAST1;
DR   GuidetoPHARMACOLOGY; 868; -.
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0005314; F:high-affinity glutamate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0031223; P:auditory behavior; IEA:Ensembl.
DR   GO; GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021545; P:cranial nerve development; IEA:Ensembl.
DR   GO; GO:0070779; P:D-aspartate import; IDA:UniProtKB.
DR   GO; GO:0009449; P:gamma-aminobutyric acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0051938; P:L-glutamate import; IDA:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0001504; P:neurotransmitter uptake; TAS:ProtInc.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   EAA2_HUMAN              Reviewed;         574 AA.
AC   P43004; B4DQE9; Q14417; Q541G6; U3KQQ4;
DE   RecName: Full=Excitatory amino acid transporter 2;
DE   AltName: Full=Glutamate/aspartate transporter II;
DE   AltName: Full=Sodium-dependent glutamate/aspartate transporter 2;
DE   AltName: Full=Solute carrier family 1 member 2;
GN   Name=SLC1A2; Synonyms=EAAT2, GLT1;
DR   GuidetoPHARMACOLOGY; 869; -.
DR   GO; GO:0015501; F:glutamate:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0070779; P:D-aspartate import; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0051938; P:L-glutamate import; IDA:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007632; P:visual behavior; IEA:Ensembl.
//
ID   EAA3_HUMAN              Reviewed;         524 AA.
AC   P43005; O75587; Q5VZ24; Q8N199; Q9UEW2;
DE   RecName: Full=Excitatory amino acid transporter 3;
DE   AltName: Full=Excitatory amino-acid carrier 1;
DE   AltName: Full=Neuronal and epithelial glutamate transporter;
DE   AltName: Full=Sodium-dependent glutamate/aspartate transporter 3;
DE   AltName: Full=Solute carrier family 1 member 1;
GN   Name=SLC1A1; Synonyms=EAAC1, EAAT3;
DR   GuidetoPHARMACOLOGY; 870; -.
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0015501; F:glutamate:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0070779; P:D-aspartate import; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0051938; P:L-glutamate import; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   EAA4_HUMAN              Reviewed;         564 AA.
AC   P48664;
DE   RecName: Full=Excitatory amino acid transporter 4;
DE   AltName: Full=Sodium-dependent glutamate/aspartate transporter;
DE   AltName: Full=Solute carrier family 1 member 6;
GN   Name=SLC1A6; Synonyms=EAAT4;
DR   GuidetoPHARMACOLOGY; 871; -.
DR   GO; GO:0015183; F:L-aspartate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0015810; P:aspartate transport; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015813; P:L-glutamate transport; TAS:ProtInc.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   EAA5_HUMAN              Reviewed;         560 AA.
AC   O00341; Q5VVZ0; Q969Z8;
DE   RecName: Full=Excitatory amino acid transporter 5;
DE   AltName: Full=Retinal glutamate transporter;
DE   AltName: Full=Solute carrier family 1 member 7;
GN   Name=SLC1A7; Synonyms=EAAT5;
DR   GuidetoPHARMACOLOGY; 872; -.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0006835; P:dicarboxylic acid transport; TAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015813; P:L-glutamate transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   EAF1_HUMAN              Reviewed;         268 AA.
AC   Q96JC9; Q8IW10;
DE   RecName: Full=ELL-associated factor 1;
GN   Name=EAF1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EAF2_HUMAN              Reviewed;         260 AA.
AC   Q96CJ1; Q9NZ82;
DE   RecName: Full=ELL-associated factor 2;
DE   AltName: Full=Testosterone-regulated apoptosis inducer and tumor suppressor protein;
GN   Name=EAF2; Synonyms=TRAITS; ORFNames=BM-040;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EAF6_HUMAN              Reviewed;         191 AA.
AC   Q9HAF1; B1AK64; Q4F967; Q7Z311; Q86WE3;
DE   RecName: Full=Chromatin modification-related protein MEAF6;
DE            Short=MYST/Esa1-associated factor 6;
DE   AltName: Full=Esa1-associated factor 6 homolog;
DE            Short=Protein EAF6 homolog;
DE            Short=hEAF6;
DE   AltName: Full=Sarcoma antigen NY-SAR-91;
GN   Name=MEAF6; Synonyms=C1orf149, EAF6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0044154; P:histone H3-K14 acetylation; IDA:UniProtKB.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EAPP_HUMAN              Reviewed;         285 AA.
AC   Q56P03; Q9BVF4; Q9NWV5; Q9NZ86;
DE   RecName: Full=E2F-associated phosphoprotein;
DE            Short=EAPP;
GN   Name=EAPP; Synonyms=C14orf11; ORFNames=BM-036;
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:MGI.
//
ID   EBLN2_HUMAN             Reviewed;         272 AA.
AC   Q6P2I7; Q8WWH3; Q9NW89;
DE   RecName: Full=Endogenous Bornavirus-like nucleoprotein 2;
DE   AltName: Full=Endogenous Borna-like N element-2;
DE            Short=EBLN-2;
GN   Name=EBLN2; ORFNames=GK006;
//
ID   EBLN1_HUMAN             Reviewed;         366 AA.
AC   P0CF75; S4R316;
DE   RecName: Full=Endogenous Bornavirus-like nucleoprotein 1;
DE   AltName: Full=Endogenous Borna-like N element-1;
DE            Short=EBLN-1;
GN   Name=EBLN1;
//
ID   EBP2_HUMAN              Reviewed;         306 AA.
AC   Q99848; Q96A66;
DE   RecName: Full=Probable rRNA-processing protein EBP2;
DE   AltName: Full=EBNA1-binding protein 2;
DE   AltName: Full=Nucleolar protein p40;
GN   Name=EBNA1BP2; Synonyms=EBP2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   EBPL_HUMAN              Reviewed;         206 AA.
AC   Q9BY08; A6NJ59; Q569H7; Q5JVN2; Q5JVN3; Q5JVN4; Q5JVN5; Q5JVN6;
DE   RecName: Full=Emopamil-binding protein-like;
DE   AltName: Full=Emopamil-binding-related protein;
GN   Name=EBPL; Synonyms=EBRP, ERP;
DR   GO; GO:0047750; F:cholestenol delta-isomerase activity; IEA:InterPro.
DR   GO; GO:0016125; P:sterol metabolic process; IEA:InterPro.
//
ID   EBP_HUMAN               Reviewed;         230 AA.
AC   Q15125; Q6FGL3; Q6IBI9;
DE   RecName: Full=3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase;
DE            EC=5.3.3.5;
DE   AltName: Full=Cholestenol Delta-isomerase;
DE   AltName: Full=Delta(8)-Delta(7) sterol isomerase;
DE            Short=D8-D7 sterol isomerase;
DE   AltName: Full=Emopamil-binding protein;
GN   Name=EBP;
DR   GO; GO:0000247; F:C-8 sterol isomerase activity; IEA:Ensembl.
DR   GO; GO:0047750; F:cholestenol delta-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015238; F:drug transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0004769; F:steroid delta-isomerase activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0006855; P:drug transmembrane transport; TAS:GOC.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ECE1_HUMAN              Reviewed;         770 AA.
AC   P42892; A8K3P1; B4E291; Q14217; Q17RN5; Q2Z2K8; Q58GE7; Q5THM5;
AC   Q5THM7; Q5THM8; Q9UJQ6; Q9UPF4; Q9UPM4; Q9Y501;
DE   RecName: Full=Endothelin-converting enzyme 1;
DE            Short=ECE-1;
DE            EC=3.4.24.71;
GN   Name=ECE1;
DR   GuidetoPHARMACOLOGY; 1615; -.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; ISS:BHF-UCL.
DR   GO; GO:0017046; F:peptide hormone binding; IC:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0010815; P:bradykinin catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010816; P:calcitonin catabolic process; IDA:BHF-UCL.
DR   GO; GO:0043583; P:ear development; IMP:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0034959; P:endothelin maturation; IDA:BHF-UCL.
DR   GO; GO:0007507; P:heart development; IMP:BHF-UCL.
DR   GO; GO:0042447; P:hormone catabolic process; IDA:BHF-UCL.
DR   GO; GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IMP:BHF-UCL.
DR   GO; GO:0016485; P:protein processing; IDA:BHF-UCL.
DR   GO; GO:0003100; P:regulation of systemic arterial blood pressure by endothelin; IC:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IC:BHF-UCL.
DR   GO; GO:0010814; P:substance P catabolic process; IDA:BHF-UCL.
//
ID   ECE2_HUMAN              Reviewed;         883 AA.
AC   O60344; A5PLK8; Q6NTG7; Q6UW36; Q8NFD7; Q96NX3; Q96NX4; Q9BRZ8;
DE   RecName: Full=Endothelin-converting enzyme 2;
DE            Short=ECE-2;
DE   Includes:
DE     RecName: Full=Methyltransferase-like region;
DE              EC=2.1.1.-;
DE   Includes:
DE     RecName: Full=Endothelin-converting enzyme 2 region;
DE              EC=3.4.24.71;
GN   Name=ECE2; Synonyms=KIAA0604; ORFNames=UNQ403/PRO740;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0010002; P:cardioblast differentiation; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0016486; P:peptide hormone processing; IDA:UniProtKB.
//
ID   ECEL1_HUMAN             Reviewed;         775 AA.
AC   O95672; Q45UD9; Q53RF9; Q6UW86; Q86TH4; Q9NY95;
DE   RecName: Full=Endothelin-converting enzyme-like 1;
DE            EC=3.4.24.-;
DE   AltName: Full=Xce protein;
GN   Name=ECEL1; Synonyms=XCE; ORFNames=UNQ2431/PRO4991;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0003016; P:respiratory system process; ISS:UniProtKB.
//
ID   ECH1_HUMAN              Reviewed;         328 AA.
AC   Q13011; A8K745; Q8WVX0; Q96EZ9;
DE   RecName: Full=Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial;
DE            EC=5.3.3.-;
DE   Flags: Precursor;
GN   Name=ECH1;
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
//
ID   ECHA_HUMAN              Reviewed;         763 AA.
AC   P40939; B2R7L4; B4DYP2; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5;
DE   RecName: Full=Trifunctional enzyme subunit alpha, mitochondrial;
DE   AltName: Full=78 kDa gastrin-binding protein;
DE   AltName: Full=TP-alpha;
DE   Includes:
DE     RecName: Full=Long-chain enoyl-CoA hydratase;
DE              EC=4.2.1.17;
DE   Includes:
DE     RecName: Full=Long chain 3-hydroxyacyl-CoA dehydrogenase;
DE              EC=1.1.1.211;
DE   Flags: Precursor;
GN   Name=HADHA; Synonyms=HADH;
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:Ensembl.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:Ensembl.
DR   GO; GO:0016509; F:long-chain-3-hydroxyacyl-CoA dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0016508; F:long-chain-enoyl-CoA hydratase activity; IEA:Ensembl.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ECHB_HUMAN              Reviewed;         474 AA.
AC   P55084; B2RB16; B4E2W0; O14969; Q53TA6; Q96C77; Q9H3F5; Q9T2V8;
DE   RecName: Full=Trifunctional enzyme subunit beta, mitochondrial;
DE   AltName: Full=TP-beta;
DE   Includes:
DE     RecName: Full=3-ketoacyl-CoA thiolase;
DE              EC=2.3.1.16;
DE     AltName: Full=Acetyl-CoA acyltransferase;
DE     AltName: Full=Beta-ketothiolase;
DE   Flags: Precursor;
GN   Name=HADHB; ORFNames=MSTP029;
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; TAS:ProtInc.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; TAS:ProtInc.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:Ensembl.
DR   GO; GO:0016509; F:long-chain-3-hydroxyacyl-CoA dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0016508; F:long-chain-enoyl-CoA hydratase activity; IEA:Ensembl.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ECHD1_HUMAN             Reviewed;         307 AA.
AC   Q9NTX5; A6NFJ5; B7Z8S0; E9PEN7; E9PR31; F8W851; Q5TEF6; Q5TEF7;
AC   Q5TEG0; Q5TEG4; Q9NZ30; V9HW18;
DE   RecName: Full=Ethylmalonyl-CoA decarboxylase;
DE            EC=4.1.1.94;
DE   AltName: Full=Enoyl-CoA hydratase domain-containing protein 1;
DE   AltName: Full=Methylmalonyl-CoA decarboxylase;
DE            Short=MMCD;
DE            EC=4.1.1.41;
GN   Name=ECHDC1;
DR   GO; GO:0016831; F:carboxy-lyase activity; ISS:UniProtKB.
DR   GO; GO:0004492; F:methylmalonyl-CoA decarboxylase activity; IEA:UniProtKB-EC.
//
ID   ECHD2_HUMAN             Reviewed;         292 AA.
AC   Q86YB7; D3DQ36; Q9NV38;
DE   RecName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial;
DE   Flags: Precursor;
GN   Name=ECHDC2;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   ECHD3_HUMAN             Reviewed;         303 AA.
AC   Q96DC8; Q53HR9; Q5W0J7; Q8WYY8; Q9BVL8; Q9H7G4;
DE   RecName: Full=Enoyl-CoA hydratase domain-containing protein 3, mitochondrial;
DE   Flags: Precursor;
GN   Name=ECHDC3; ORFNames=PP1494, PP8332;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   ECHM_HUMAN              Reviewed;         290 AA.
AC   P30084; O00739; Q5VWY1; Q96H54;
DE   RecName: Full=Enoyl-CoA hydratase, mitochondrial;
DE            EC=4.2.1.17;
DE   AltName: Full=Enoyl-CoA hydratase 1;
DE   AltName: Full=Short-chain enoyl-CoA hydratase;
DE            Short=SCEH;
DE   Flags: Precursor;
GN   Name=ECHS1;
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ECHP_HUMAN              Reviewed;         723 AA.
AC   Q08426; A8K6Y3; B4DWG3; D3DNU0; Q58EZ5;
DE   RecName: Full=Peroxisomal bifunctional enzyme;
DE            Short=PBE;
DE            Short=PBFE;
DE   Includes:
DE     RecName: Full=Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase;
DE              EC=4.2.1.17;
DE              EC=5.3.3.8;
DE   Includes:
DE     RecName: Full=3-hydroxyacyl-CoA dehydrogenase;
DE              EC=1.1.1.35;
GN   Name=EHHADH; Synonyms=ECHD;
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; NAS:UniProtKB.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0004165; F:dodecenoyl-CoA delta-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004300; F:enoyl-CoA hydratase activity; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; NAS:UniProtKB.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; IDA:UniProtKB.
//
ID   ECI1_HUMAN              Reviewed;         302 AA.
AC   P42126; A8K512; Q13290; Q7Z2L6; Q7Z2L7; Q9BUB8; Q9BW05; Q9UDG6;
DE   RecName: Full=Enoyl-CoA delta isomerase 1, mitochondrial;
DE            EC=5.3.3.8;
DE   AltName: Full=3,2-trans-enoyl-CoA isomerase;
DE   AltName: Full=Delta(3),Delta(2)-enoyl-CoA isomerase;
DE            Short=D3,D2-enoyl-CoA isomerase;
DE   AltName: Full=Dodecenoyl-CoA isomerase;
DE   Flags: Precursor;
GN   Name=ECI1; Synonyms=DCI;
DR   GO; GO:0004165; F:dodecenoyl-CoA delta-isomerase activity; NAS:UniProtKB.
DR   GO; GO:0016860; F:intramolecular oxidoreductase activity; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ECI2_HUMAN              Reviewed;         394 AA.
AC   O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1;
AC   Q9NYH7; Q9UN55;
DE   RecName: Full=Enoyl-CoA delta isomerase 2, mitochondrial;
DE            EC=5.3.3.8;
DE   AltName: Full=DRS-1;
DE   AltName: Full=Delta(3),delta(2)-enoyl-CoA isomerase;
DE            Short=D3,D2-enoyl-CoA isomerase;
DE   AltName: Full=Diazepam-binding inhibitor-related protein 1;
DE            Short=DBI-related protein 1;
DE   AltName: Full=Dodecenoyl-CoA isomerase;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 88;
DE   AltName: Full=Peroxisomal 3,2-trans-enoyl-CoA isomerase;
DE            Short=pECI;
DE   AltName: Full=Renal carcinoma antigen NY-REN-1;
DE   Flags: Precursor;
GN   Name=ECI2; Synonyms=DRS1, HCA88, PECI;
DR   GO; GO:0004165; F:dodecenoyl-CoA delta-isomerase activity; IDA:UniProtKB.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0009062; P:fatty acid catabolic process; IDA:UniProtKB.
//
ID   ECM1_HUMAN              Reviewed;         540 AA.
AC   Q16610; A8K8S0; B4DW49; B4DY60; O43266; Q5T5G4; Q5T5G5; Q5T5G6;
AC   Q8IZ60;
DE   RecName: Full=Extracellular matrix protein 1;
DE   AltName: Full=Secretory component p85;
DE   Flags: Precursor;
GN   Name=ECM1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0043236; F:laminin binding; IPI:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:2000404; P:regulation of T cell migration; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0002828; P:regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   ECM29_HUMAN             Reviewed;        1845 AA.
AC   Q5VYK3; O15074; Q8WU82;
DE   RecName: Full=Proteasome-associated protein ECM29 homolog;
DE            Short=Ecm29;
GN   Name=ECM29; Synonyms=KIAA0368;
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   ECM2_HUMAN              Reviewed;         699 AA.
AC   O94769; B2R730; E2PU11; Q5T9F2; Q7Z3D0;
DE   RecName: Full=Extracellular matrix protein 2;
DE   AltName: Full=Matrix glycoprotein SC1/ECM2;
DE   Flags: Precursor;
GN   Name=ECM2;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   ECP_HUMAN               Reviewed;         160 AA.
AC   P12724; Q4VBC1; Q8WTP7; Q8WZ62; Q9GZN9;
DE   RecName: Full=Eosinophil cationic protein;
DE            Short=ECP;
DE            EC=3.1.27.-;
DE   AltName: Full=Ribonuclease 3;
DE            Short=RNase 3;
DE   Flags: Precursor;
GN   Name=RNASE3; Synonyms=ECP, RNS3;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004540; F:ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
//
ID   ECSCR_HUMAN             Reviewed;         205 AA.
AC   Q19T08; B4E3H7; C3RSF2;
DE   RecName: Full=Endothelial cell-specific chemotaxis regulator;
DE   AltName: Full=Apoptosis regulator through modulating IAP expression;
DE            Short=ARIA;
DE   AltName: Full=Endothelial cell-specific molecule 2;
DE   Flags: Precursor;
GN   Name=ECSCR; Synonyms=ECSM2;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   ECSIT_HUMAN             Reviewed;         431 AA.
AC   Q9BQ95; E9PAN9; Q96HQ7; Q9NYI1;
DE   RecName: Full=Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial;
DE   AltName: Full=Protein SITPEC;
DE   Flags: Precursor;
GN   Name=ECSIT;
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0051341; P:regulation of oxidoreductase activity; IDA:UniProtKB.
//
ID   ECT2L_HUMAN             Reviewed;         904 AA.
AC   Q008S8; B2RUV6; Q5JWK2; Q5JWK3; Q5JWK4;
DE   RecName: Full=Epithelial cell-transforming sequence 2 oncogene-like;
DE   AltName: Full=Lung-specific F-box and DH domain-containing protein;
DE   AltName: Full=Putative guanine nucleotide exchange factor LFDH;
GN   Name=ECT2L; Synonyms=C6orf91, LFDH;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   ECT2_HUMAN              Reviewed;         914 AA.
AC   Q9H8V3; Q0MT80; Q2M269; Q6U836; Q9NSV8; Q9NVW9;
DE   RecName: Full=Protein ECT2;
DE   AltName: Full=Epithelial cell-transforming sequence 2 oncogene;
GN   Name=ECT2;
DR   GO; GO:0005096; F:GTPase activator activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; IMP:UniProtKB.
//
ID   EDAD_HUMAN              Reviewed;         215 AA.
AC   Q8WWZ3; A2VCK5; A8K7B5; B1AL54; B9ZVW5; Q5VYJ7;
DE   RecName: Full=Ectodysplasin-A receptor-associated adapter protein;
DE   AltName: Full=EDAR-associated death domain protein;
DE   AltName: Full=Protein crinkled homolog;
GN   Name=EDARADD;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0061153; P:trachea gland development; IEA:Ensembl.
//
ID   EDAR_HUMAN              Reviewed;         448 AA.
AC   Q9UNE0; B2R9H2; B4DLC5; D3DX74; E9PC98; Q52LL5; Q9UND9;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member EDAR;
DE   AltName: Full=Anhidrotic ectodysplasin receptor 1;
DE   AltName: Full=Downless homolog;
DE   AltName: Full=EDA-A1 receptor;
DE   AltName: Full=Ectodermal dysplasia receptor;
DE   AltName: Full=Ectodysplasin-A receptor;
DE   Flags: Precursor;
GN   Name=EDAR; Synonyms=DL;
DR   GuidetoPHARMACOLOGY; 2325; -.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0004872; F:receptor activity; IDA:HGNC.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; TAS:HGNC.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
//
ID   EDA_HUMAN               Reviewed;         391 AA.
AC   Q92838; A0AUZ2; A2A337; B7ZLU2; B7ZLU4; O75910; Q5JS00; Q5JUM7;
AC   Q9UP77; Q9Y6L0; Q9Y6L1; Q9Y6L2; Q9Y6L3; Q9Y6L4;
DE   RecName: Full=Ectodysplasin-A;
DE   AltName: Full=Ectodermal dysplasia protein;
DE            Short=EDA protein;
DE   Contains:
DE     RecName: Full=Ectodysplasin-A, membrane form;
DE   Contains:
DE     RecName: Full=Ectodysplasin-A, secreted form;
GN   Name=EDA; Synonyms=ED1, EDA2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:HGNC.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; IEA:Ensembl.
DR   GO; GO:0060789; P:hair follicle placode formation; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:HGNC.
DR   GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0061153; P:trachea gland development; IEA:Ensembl.
//
ID   EDC3_HUMAN              Reviewed;         508 AA.
AC   Q96F86; B3KPH0; D3DW61; Q9H797;
DE   RecName: Full=Enhancer of mRNA-decapping protein 3;
DE   AltName: Full=LSM16 homolog;
DE   AltName: Full=YjeF N-terminal domain-containing protein 2;
DE            Short=YjeF_N2;
DE            Short=hYjeF_N2;
DE   AltName: Full=YjeF domain-containing protein 1;
GN   Name=EDC3; Synonyms=LSM16, YJDC, YJEFN2; ORFNames=PP844;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   EDC4_HUMAN              Reviewed;        1401 AA.
AC   Q6P2E9; A6NGM1; A8K4T4; Q13025; Q13826; Q6ZR12; Q7Z6H7;
DE   RecName: Full=Enhancer of mRNA-decapping protein 4;
DE   AltName: Full=Autoantigen Ge-1;
DE   AltName: Full=Autoantigen RCD-8;
DE   AltName: Full=Human enhancer of decapping large subunit;
DE            Short=Hedls;
GN   Name=EDC4; Synonyms=HEDLS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   EDEM1_HUMAN             Reviewed;         657 AA.
AC   Q92611; A8K9C8;
DE   RecName: Full=ER degradation-enhancing alpha-mannosidase-like protein 1;
GN   Name=EDEM1; Synonyms=EDEM, KIAA0212;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0051787; F:misfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   EDEM2_HUMAN             Reviewed;         578 AA.
AC   Q9BV94; B4DTG9; Q6GU33; Q6IA89; Q6UWZ4; Q9H4U0; Q9H886; Q9NTL9;
AC   Q9NVE6;
DE   RecName: Full=ER degradation-enhancing alpha-mannosidase-like protein 2;
DE   Flags: Precursor;
GN   Name=EDEM2; Synonyms=C20orf31, C20orf49; ORFNames=UNQ573/PRO1135;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   EDEM3_HUMAN             Reviewed;         932 AA.
AC   Q9BZQ6; B2RCH6; Q0VGM5; Q5TEZ0; Q9HCW1; Q9UFV7;
DE   RecName: Full=ER degradation-enhancing alpha-mannosidase-like protein 3;
DE            EC=3.2.1.113;
DE   AltName: Full=Alpha-1,2-mannosidase EDEM3;
DE   Flags: Precursor;
GN   Name=EDEM3; Synonyms=C1orf22;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004569; F:glycoprotein endo-alpha-1,2-mannosidase activity; IEA:Ensembl.
DR   GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   EDF1_HUMAN              Reviewed;         148 AA.
AC   O60869; Q5T5T2; Q9UIM1;
DE   RecName: Full=Endothelial differentiation-related factor 1;
DE            Short=EDF-1;
DE   AltName: Full=Multiprotein-bridging factor 1;
DE            Short=MBF1;
GN   Name=EDF1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0045446; P:endothelial cell differentiation; TAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EDIL3_HUMAN             Reviewed;         480 AA.
AC   O43854; B2R763; O43855; Q5D094; Q8N610;
DE   RecName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3;
DE   AltName: Full=Developmentally-regulated endothelial cell locus 1 protein;
DE   AltName: Full=Integrin-binding protein DEL1;
DE   Flags: Precursor;
GN   Name=EDIL3; Synonyms=DEL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   EDN1_HUMAN              Reviewed;         212 AA.
AC   P05305; Q96DA1;
DE   RecName: Full=Endothelin-1;
DE   AltName: Full=Preproendothelin-1;
DE            Short=PPET1;
DE   Contains:
DE     RecName: Full=Endothelin-1;
DE              Short=ET-1;
DE   Contains:
DE     RecName: Full=Big endothelin-1;
DE   Flags: Precursor;
GN   Name=EDN1;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0031707; F:endothelin A receptor binding; IDA:BHF-UCL.
DR   GO; GO:0031708; F:endothelin B receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0007589; P:body fluid secretion; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0042045; P:epithelial fluid transport; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0001821; P:histamine secretion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0045321; P:leukocyte activation; TAS:BHF-UCL.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; TAS:BHF-UCL.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032269; P:negative regulation of cellular protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0051771; P:negative regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0034392; P:negative regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0030185; P:nitric oxide transport; IDA:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0030072; P:peptide hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0031583; P:phospholipase D-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045793; P:positive regulation of cell size; IDA:BHF-UCL.
DR   GO; GO:0070101; P:positive regulation of chemokine-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:BHF-UCL.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; TAS:BHF-UCL.
DR   GO; GO:0010460; P:positive regulation of heart rate; IDA:BHF-UCL.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0042482; P:positive regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0060585; P:positive regulation of prostaglandin-endoperoxide synthase activity; IMP:BHF-UCL.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0060298; P:positive regulation of sarcomere organization; IMP:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0035810; P:positive regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0042313; P:protein kinase C deactivation; IDA:BHF-UCL.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0003100; P:regulation of systemic arterial blood pressure by endothelin; IDA:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0043179; P:rhythmic excitation; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0042310; P:vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0014826; P:vein smooth muscle contraction; IDA:BHF-UCL.
//
ID   EDN2_HUMAN              Reviewed;         178 AA.
AC   P20800; Q5T1R3;
DE   RecName: Full=Endothelin-2;
DE            Short=ET-2;
DE   AltName: Full=Preproendothelin-2;
DE            Short=PPET2;
DE   Flags: Precursor;
GN   Name=EDN2;
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0003058; P:hormonal regulation of the force of heart contraction; TAS:BHF-UCL.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0042116; P:macrophage activation; IDA:BHF-UCL.
DR   GO; GO:0048246; P:macrophage chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:BHF-UCL.
DR   GO; GO:0010460; P:positive regulation of heart rate; IDA:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0060585; P:positive regulation of prostaglandin-endoperoxide synthase activity; IMP:BHF-UCL.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0003099; P:positive regulation of the force of heart contraction by chemical signal; TAS:BHF-UCL.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0003100; P:regulation of systemic arterial blood pressure by endothelin; IDA:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0042310; P:vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0014826; P:vein smooth muscle contraction; IDA:BHF-UCL.
//
ID   EDN3_HUMAN              Reviewed;         238 AA.
AC   P14138; E1P5I5; Q03229; Q7Z6D2; Q9UGT7;
DE   RecName: Full=Endothelin-3;
DE            Short=ET-3;
DE   AltName: Full=Preproendothelin-3;
DE            Short=PPET3;
DE   Flags: Precursor;
GN   Name=EDN3;
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0030072; P:peptide hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IDA:BHF-UCL.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:BHF-UCL.
DR   GO; GO:0048070; P:regulation of developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0003100; P:regulation of systemic arterial blood pressure by endothelin; IDA:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042310; P:vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0014826; P:vein smooth muscle contraction; IDA:BHF-UCL.
//
ID   EDNRA_HUMAN             Reviewed;         427 AA.
AC   P25101; B2R723; B4E2V6; B7Z9G6; D3DP03; E7ER36; O43441; Q16432;
AC   Q16433; Q8TBH2;
DE   RecName: Full=Endothelin-1 receptor;
DE   AltName: Full=Endothelin A receptor;
DE            Short=ET-A;
DE            Short=ETA-R;
DE            Short=hET-AR;
DE   Flags: Precursor;
GN   Name=EDNRA; Synonyms=ETA, ETRA;
DR   GuidetoPHARMACOLOGY; 219; -.
DR   GO; GO:0004962; F:endothelin receptor activity; NAS:UniProtKB.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:InterPro.
DR   GO; GO:0048144; P:fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0003094; P:glomerular filtration; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; ISS:UniProtKB.
DR   GO; GO:0060322; P:head development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0001821; P:histamine secretion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0043084; P:penile erection; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0090184; P:positive regulation of kidney development; IEA:Ensembl.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0042482; P:positive regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:InterPro.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; ISS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048659; P:smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0006939; P:smooth muscle contraction; NAS:UniProtKB.
DR   GO; GO:0042310; P:vasoconstriction; IMP:BHF-UCL.
//
ID   EDNRB_HUMAN             Reviewed;         442 AA.
AC   P24530; A2A2Z8; A8K3T4; O15343; Q59GB1; Q5W0G9; Q8NHM6; Q8NHM7;
AC   Q8NHM8; Q8NHM9; Q9UD23; Q9UQK3;
DE   RecName: Full=Endothelin B receptor;
DE            Short=ET-B;
DE            Short=ET-BR;
DE   AltName: Full=Endothelin receptor non-selective type;
DE   Flags: Precursor;
GN   Name=EDNRB; Synonyms=ETRB;
DR   GuidetoPHARMACOLOGY; 220; -.
DR   GO; GO:0004962; F:endothelin receptor activity; IDA:BHF-UCL.
DR   GO; GO:0017046; F:peptide hormone binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0019934; P:cGMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0086100; P:endothelin receptor signaling pathway; IDA:GOC.
DR   GO; GO:0048484; P:enteric nervous system development; ISS:BHF-UCL.
DR   GO; GO:0035645; P:enteric smooth muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0042045; P:epithelial fluid transport; IEA:Ensembl.
DR   GO; GO:0048246; P:macrophage chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032269; P:negative regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0014043; P:negative regulation of neuron maturation; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0060406; P:positive regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0035810; P:positive regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0007497; P:posterior midgut development; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0031620; P:regulation of fever generation; IEA:Ensembl.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0042310; P:vasoconstriction; IMP:BHF-UCL.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
DR   GO; GO:0014826; P:vein smooth muscle contraction; IMP:BHF-UCL.
//
ID   EDRF1_HUMAN             Reviewed;        1238 AA.
AC   Q3B7T1; B2RC65; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4;
DE   RecName: Full=Erythroid differentiation-related factor 1;
GN   Name=EDRF1; Synonyms=C10orf137;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EEA1_HUMAN              Reviewed;        1411 AA.
AC   Q15075; Q14221;
DE   RecName: Full=Early endosome antigen 1;
DE   AltName: Full=Endosome-associated protein p162;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 2;
GN   Name=EEA1; Synonyms=ZFYVE2;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; NAS:UniProtKB.
DR   GO; GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0016189; P:synaptic vesicle to endosome fusion; TAS:UniProtKB.
DR   GO; GO:0006906; P:vesicle fusion; IMP:UniProtKB.
//
ID   EED_HUMAN               Reviewed;         441 AA.
AC   O75530; A8K7V5; O00149; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7;
DE   RecName: Full=Polycomb protein EED;
DE            Short=hEED;
DE   AltName: Full=WD protein associating with integrin cytoplasmic tails 1;
DE            Short=WAIT-1;
GN   Name=EED;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:MGI.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0061087; P:positive regulation of histone H3-K27 methylation; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EEPD1_HUMAN             Reviewed;         569 AA.
AC   Q7L9B9; Q96K64; Q9C0F7;
DE   RecName: Full=Endonuclease/exonuclease/phosphatase family domain-containing protein 1;
GN   Name=EEPD1; Synonyms=KIAA1706;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
//
ID   EF1A1_HUMAN             Reviewed;         462 AA.
AC   P68104; P04719; P04720;
DE   RecName: Full=Elongation factor 1-alpha 1;
DE            Short=EF-1-alpha-1;
DE   AltName: Full=Elongation factor Tu;
DE            Short=EF-Tu;
DE   AltName: Full=Eukaryotic elongation factor 1 A-1;
DE            Short=eEF1A-1;
DE   AltName: Full=Leukocyte receptor cluster member 7;
GN   Name=EEF1A1; Synonyms=EEF1A, EF1A, LENG7;
DR   GO; GO:0005525; F:GTP binding; TAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006414; P:translational elongation; TAS:UniProtKB.
//
ID   EF1A2_HUMAN             Reviewed;         463 AA.
AC   Q05639; B5BUF3; E1P5J1; P54266; Q0VGC7;
DE   RecName: Full=Elongation factor 1-alpha 2;
DE            Short=EF-1-alpha-2;
DE   AltName: Full=Eukaryotic elongation factor 1 A-2;
DE            Short=eEF1A-2;
DE   AltName: Full=Statin-S1;
GN   Name=EEF1A2; Synonyms=EEF1AL, STN;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; NAS:ProtInc.
DR   GO; GO:1900119; P:positive regulation of execution phase of apoptosis; IEA:Ensembl.
DR   GO; GO:0010035; P:response to inorganic substance; IEA:Ensembl.
//
ID   EF1A3_HUMAN             Reviewed;         462 AA.
AC   Q5VTE0;
DE   RecName: Full=Putative elongation factor 1-alpha-like 3;
DE            Short=EF-1-alpha-like 3;
DE   AltName: Full=Eukaryotic elongation factor 1 A-like 3;
DE            Short=eEF1A-like 3;
DE   AltName: Full=Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5;
GN   Name=EEF1A1P5; Synonyms=EEF1AL3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
//
ID   EF1B_HUMAN              Reviewed;         225 AA.
AC   P24534; A8K795; Q6IBH9;
DE   RecName: Full=Elongation factor 1-beta;
DE            Short=EF-1-beta;
GN   Name=EEF1B2; Synonyms=EEF1B, EF1B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003746; F:translation elongation factor activity; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006414; P:translational elongation; NAS:UniProtKB.
//
ID   EF1DL_HUMAN             Reviewed;         133 AA.
AC   Q658K8; Q08AR3;
DE   RecName: Full=Putative elongation factor 1-delta-like protein;
DE            Short=Putative EF-1-delta-like pseudogene 3 protein;
GN   Name=EEF1DP3;
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
//
ID   EF1D_HUMAN              Reviewed;         281 AA.
AC   P29692; B4DDU4; D3DWK3; E9PBQ9; Q4VBZ6; Q969J1; Q96I38;
DE   RecName: Full=Elongation factor 1-delta;
DE            Short=EF-1-delta;
DE   AltName: Full=Antigen NY-CO-4;
GN   Name=EEF1D; Synonyms=EF1D;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
//
ID   EF1G_HUMAN              Reviewed;         437 AA.
AC   P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196;
DE   RecName: Full=Elongation factor 1-gamma;
DE            Short=EF-1-gamma;
DE   AltName: Full=eEF-1B gamma;
GN   Name=EEF1G; Synonyms=EF1G; ORFNames=PRO1608;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
//
ID   EF2K_HUMAN              Reviewed;         725 AA.
AC   O00418; Q8N588;
DE   RecName: Full=Eukaryotic elongation factor 2 kinase;
DE            Short=eEF-2 kinase;
DE            Short=eEF-2K;
DE            EC=2.7.11.20;
DE   AltName: Full=Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase;
GN   Name=EEF2K;
DR   GuidetoPHARMACOLOGY; 2014; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0004686; F:elongation factor-2 kinase activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0031952; P:regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006414; P:translational elongation; TAS:ProtInc.
//
ID   EF2_HUMAN               Reviewed;         858 AA.
AC   P13639; B2RMP5; D6W618; Q58J86;
DE   RecName: Full=Elongation factor 2;
DE            Short=EF-2;
GN   Name=EEF2; Synonyms=EF2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProt.
DR   GO; GO:0008494; F:translation activator activity; IGI:UniProt.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0010628; P:positive regulation of gene expression; IGI:UniProt.
DR   GO; GO:0045727; P:positive regulation of translation; IGI:UniProt.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
//
ID   EFC10_HUMAN             Reviewed;         127 AA.
AC   A6NFE3;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 10;
GN   Name=EFCAB10;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFC11_HUMAN             Reviewed;         163 AA.
AC   Q9BUY7; B3KT10; B7Z5G9; Q86T09; Q86TV7; Q8NDQ1;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 11;
GN   Name=EFCAB11; Synonyms=C14orf143;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFC12_HUMAN             Reviewed;         572 AA.
AC   Q6NXP0; Q69YX4;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 12;
GN   Name=EFCAB12; Synonyms=C3orf25;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFC13_HUMAN             Reviewed;         973 AA.
AC   Q8IY85; G3V128; Q49AG9;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 13;
GN   Name=EFCAB13; Synonyms=C17orf57;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFC14_HUMAN             Reviewed;         495 AA.
AC   O75071; D3DQ23; Q5SXB8;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 14;
GN   Name=EFCAB14; Synonyms=KIAA0494;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFC2_HUMAN              Reviewed;         527 AA.
AC   P60608;
DE   RecName: Full=HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein;
DE   AltName: Full=Endogenous retrovirus group FC1 member 1;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=Fc2deltaenv;
DE   Includes:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Includes:
DE     RecName: Full=Truncated transmembrane protein;
DE              Short=TM;
GN   Name=ERVFC1-1;
//
ID   EFC4A_HUMAN             Reviewed;         399 AA.
AC   Q8N4Y2; D5LPR2; Q8NBW8;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 4A;
DE   AltName: Full=Calcium release-activated calcium channel regulator 2B;
DE            Short=CRAC channel regulator 2B;
GN   Name=EFCAB4A; Synonyms=CRACR2B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; IEA:Ensembl.
DR   GO; GO:0002115; P:store-operated calcium entry; IMP:UniProtKB.
//
ID   EFC1_HUMAN              Reviewed;         584 AA.
AC   P60507; Q5JTS0;
DE   RecName: Full=HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=Fc1env;
DE   AltName: Full=HERV-Fc1env;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
//
ID   EFC4B_HUMAN             Reviewed;         395 AA.
AC   Q9BSW2; B4E1X0; B9EK63;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 4B;
DE   AltName: Full=Calcium release-activated calcium channel regulator 2A;
DE            Short=CRAC channel regulator 2A;
GN   Name=EFCAB4B; Synonyms=CRACR2A;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032237; P:activation of store-operated calcium channel activity; IMP:UniProtKB.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0002115; P:store-operated calcium entry; IMP:UniProtKB.
//
ID   EFCB1_HUMAN             Reviewed;         211 AA.
AC   Q9HAE3; B4DSB4; E7EVN7;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 1;
GN   Name=EFCAB1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCB3_HUMAN             Reviewed;         438 AA.
AC   Q8N7B9; J3KQM8;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 3;
GN   Name=EFCAB3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCB5_HUMAN             Reviewed;        1503 AA.
AC   A4FU69; B2RPN0; B4DS75; F5GYL2; Q0VD68; Q6ZRM6; Q8NDG9;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 5;
GN   Name=EFCAB5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCB2_HUMAN             Reviewed;         269 AA.
AC   Q5VUJ9; B4DZE9; Q59G23; Q9BS36;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 2;
GN   Name=EFCAB2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCB6_HUMAN             Reviewed;        1501 AA.
AC   Q5THR3; A8K8P6; A8K8Y3; B0QYI4; B0QYI6; Q5U5T6; Q9BY88; Q9H5C4;
AC   Q9NSF5;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 6;
DE   AltName: Full=CAP-binding protein complex-interacting protein 1;
DE   AltName: Full=DJ-1-binding protein;
DE            Short=DJBP;
GN   Name=EFCAB6; Synonyms=DJBP, KIAA1672;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EFCB8_HUMAN             Reviewed;         144 AA.
AC   A8MWE9;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 8;
GN   Name=EFCAB8;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCB7_HUMAN             Reviewed;         629 AA.
AC   A8K855; Q658P0; Q96B95; Q96JM6;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 7;
GN   Name=EFCAB7; Synonyms=KIAA1799;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCC1_HUMAN             Reviewed;         598 AA.
AC   Q9HA90; A8MYE2;
DE   RecName: Full=EF-hand and coiled-coil domain-containing protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 48;
GN   Name=EFCC1; Synonyms=C3orf73, CCDC48;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFCB9_HUMAN             Reviewed;         197 AA.
AC   A8MZ26;
DE   RecName: Full=EF-hand calcium-binding domain-containing protein 9;
GN   Name=EFCAB9;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFGM_HUMAN              Reviewed;         751 AA.
AC   Q96RP9; A6NCI9; B2RCB9; B3KRW1; Q6GTN2; Q96T39;
DE   RecName: Full=Elongation factor G, mitochondrial;
DE            Short=EF-Gmt;
DE   AltName: Full=Elongation factor G 1, mitochondrial;
DE            Short=mEF-G 1;
DE   AltName: Full=Elongation factor G1;
DE            Short=hEFG1;
DE   Flags: Precursor;
GN   Name=GFM1; Synonyms=EFG, EFG1, GFM;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003746; F:translation elongation factor activity; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0070125; P:mitochondrial translational elongation; IDA:UniProtKB.
//
ID   EFHC1_HUMAN             Reviewed;         640 AA.
AC   Q5JVL4; B4DMU3; F5GZD8; Q5XKM4; Q6E1U7; Q6E1U8; Q8WUL2; Q9NVW6;
DE   RecName: Full=EF-hand domain-containing protein 1;
DE   AltName: Full=Myoclonin-1;
GN   Name=EFHC1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
//
ID   EFHB_HUMAN              Reviewed;         833 AA.
AC   Q8N7U6; A6ND25; A8MPR3; Q6ZWK9; Q8IV58; Q96LQ6;
DE   RecName: Full=EF-hand domain-containing family member B;
GN   Name=EFHB;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFHC2_HUMAN             Reviewed;         749 AA.
AC   Q5JST6; Q5JST8; Q68DK4; Q8NEI0; Q9H653;
DE   RecName: Full=EF-hand domain-containing family member C2;
GN   Name=EFHC2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EFHD2_HUMAN             Reviewed;         240 AA.
AC   Q96C19; Q5JYW9;
DE   RecName: Full=EF-hand domain-containing protein D2;
DE   AltName: Full=Swiprosin-1;
GN   Name=EFHD2; Synonyms=SWS1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
//
ID   EFHD1_HUMAN             Reviewed;         239 AA.
AC   Q9BUP0; B2RD83; E9PFH3; Q9BTF8; Q9H8I2; Q9HBQ0;
DE   RecName: Full=EF-hand domain-containing protein D1;
DE   AltName: Full=EF-hand domain-containing protein 1;
DE   AltName: Full=Swiprosin-2;
GN   Name=EFHD1; Synonyms=SWS2; ORFNames=PP3051;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
//
ID   EFNA1_HUMAN             Reviewed;         205 AA.
AC   P20827; D3DV86; Q5SR60; Q5SR61; Q6I9T9; Q8N578;
DE   RecName: Full=Ephrin-A1;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 1;
DE            Short=LERK-1;
DE   AltName: Full=Immediate early response protein B61;
DE   AltName: Full=Tumor necrosis factor alpha-induced protein 4;
DE            Short=TNF alpha-induced protein 4;
DE   Contains:
DE     RecName: Full=Ephrin-A1, secreted form;
DE   Flags: Precursor;
GN   Name=EFNA1; Synonyms=EPLG1, LERK1, TNFAIP4;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IBA:RefGenome.
DR   GO; GO:0003180; P:aortic valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0003199; P:endocardial cushion to mesenchymal transition involved in heart valve formation; ISS:BHF-UCL.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0003183; P:mitral valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0014028; P:notochord formation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045765; P:regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0043535; P:regulation of blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.
//
ID   EFNA2_HUMAN             Reviewed;         213 AA.
AC   O43921; O76020;
DE   RecName: Full=Ephrin-A2;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 6;
DE            Short=LERK-6;
DE   AltName: Full=HEK7 ligand;
DE            Short=HEK7-L;
DE   Flags: Precursor;
GN   Name=EFNA2; Synonyms=EPLG6, LERK6;
DR   GO; GO:0046875; F:ephrin receptor binding; IBA:RefGenome.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0046849; P:bone remodeling; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
//
ID   EFNA4_HUMAN             Reviewed;         201 AA.
AC   P52798; C9JHJ8; G3XAK2; O95457; Q5SR71; Q6FI57;
DE   RecName: Full=Ephrin-A4;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 4;
DE            Short=LERK-4;
DE   Flags: Precursor;
GN   Name=EFNA4; Synonyms=EPLG4, LERK4;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0046849; P:bone remodeling; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0030316; P:osteoclast differentiation; IBA:RefGenome.
//
ID   EFNA3_HUMAN             Reviewed;         238 AA.
AC   P52797; D3DV85; Q0VGC9; Q5SR70;
DE   RecName: Full=Ephrin-A3;
DE   AltName: Full=EFL-2;
DE   AltName: Full=EHK1 ligand;
DE            Short=EHK1-L;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 3;
DE            Short=LERK-3;
DE   Flags: Precursor;
GN   Name=EFNA3; Synonyms=EFL2, EPLG3, LERK3;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
//
ID   EFNA5_HUMAN             Reviewed;         228 AA.
AC   P52803;
DE   RecName: Full=Ephrin-A5;
DE   AltName: Full=AL-1;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 7;
DE            Short=LERK-7;
DE   Flags: Precursor;
GN   Name=EFNA5; Synonyms=EPLG7, LERK7;
DR   GO; GO:0045499; F:chemorepellent activity; IEA:Ensembl.
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
//
ID   EFNB1_HUMAN             Reviewed;         346 AA.
AC   P98172; D3DVU0;
DE   RecName: Full=Ephrin-B1;
DE   AltName: Full=EFL-3;
DE   AltName: Full=ELK ligand;
DE            Short=ELK-L;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 2;
DE            Short=LERK-2;
DE   Flags: Precursor;
GN   Name=EFNB1; Synonyms=EFL3, EPLG2, LERK2;
DR   GO; GO:0046875; F:ephrin receptor binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
//
ID   EFNB2_HUMAN             Reviewed;         333 AA.
AC   P52799; Q5JV56;
DE   RecName: Full=Ephrin-B2;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 5;
DE            Short=LERK-5;
DE   AltName: Full=HTK ligand;
DE            Short=HTK-L;
DE   Flags: Precursor;
GN   Name=EFNB2; Synonyms=EPLG5, HTKL, LERK5;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001945; P:lymph vessel development; IEA:Ensembl.
DR   GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:2000727; P:positive regulation of cardiac muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0050920; P:regulation of chemotaxis; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   EFNB3_HUMAN             Reviewed;         340 AA.
AC   Q15768; B2RBW2; D3DTQ6; O00680; Q8TBH7; Q92875;
DE   RecName: Full=Ephrin-B3;
DE   AltName: Full=EPH-related receptor transmembrane ligand ELK-L3;
DE   AltName: Full=EPH-related receptor tyrosine kinase ligand 8;
DE            Short=LERK-8;
DE   Flags: Precursor;
GN   Name=EFNB3; Synonyms=EPLG8, LERK8;
DR   GO; GO:0046875; F:ephrin receptor binding; IDA:MGI.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; TAS:ProtInc.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0016198; P:axon choice point recognition; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:MGI.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   EFR3A_HUMAN             Reviewed;         821 AA.
AC   Q14156; A7MD19; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18;
DE   RecName: Full=Protein EFR3 homolog A;
DE   AltName: Full=Protein EFR3-like;
GN   Name=EFR3A; Synonyms=KIAA0143;
//
ID   EFR3B_HUMAN             Reviewed;         817 AA.
AC   Q9Y2G0; B7WPL8; Q86XU6;
DE   RecName: Full=Protein EFR3 homolog B;
GN   Name=EFR3B; Synonyms=KIAA0953;
//
ID   EFRD1_HUMAN             Reviewed;         538 AA.
AC   P60508;
DE   RecName: Full=HERV-FRD_6p24.1 provirus ancestral Env polyprotein;
DE   AltName: Full=Endogenous retrovirus group FRD member 1;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-FRD;
DE   AltName: Full=Syncytin-2;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
GN   Name=ERVFRD-1; Synonyms=ERVFRDE1; ORFNames=UNQ6191/PRO20218;
//
ID   EFS_HUMAN               Reviewed;         561 AA.
AC   O43281; B2RAJ7; B4DJ56; E9PGU2; O43282;
DE   RecName: Full=Embryonal Fyn-associated substrate;
DE            Short=hEFS;
DE   AltName: Full=Cas scaffolding protein family member 3;
GN   Name=EFS; Synonyms=CASS3;
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
//
ID   EFTS_HUMAN              Reviewed;         325 AA.
AC   P43897; B4E391; F5H2T7; Q561V7; Q8TBC2; Q9UQK0;
DE   RecName: Full=Elongation factor Ts, mitochondrial;
DE            Short=EF-Ts;
DE            Short=EF-TsMt;
DE   Flags: Precursor;
GN   Name=TSFM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; TAS:ProtInc.
DR   GO; GO:0006414; P:translational elongation; TAS:ProtInc.
//
ID   EFTU_HUMAN              Reviewed;         452 AA.
AC   P49411; O15276;
DE   RecName: Full=Elongation factor Tu, mitochondrial;
DE            Short=EF-Tu;
DE   AltName: Full=P43;
DE   Flags: Precursor;
GN   Name=TUFM;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; IDA:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; IDA:UniProtKB.
//
ID   EGFEM_HUMAN             Reviewed;         195 AA.
AC   Q0D2K5;
DE   RecName: Full=Putative EGF-like and EMI domain-containing protein 1;
GN   Name=EGFEM1P; Synonyms=C3orf50, NCRNA00259;
//
ID   EGFL6_HUMAN             Reviewed;         553 AA.
AC   Q8IUX8; B2RCB1; Q6UXJ1; Q8NBV0; Q8WYG3; Q9NY67; Q9NZL7; Q9UFK6;
DE   RecName: Full=Epidermal growth factor-like protein 6;
DE            Short=EGF-like protein 6;
DE   AltName: Full=MAM and EGF domains-containing gene protein;
DE   Flags: Precursor;
GN   Name=EGFL6; Synonyms=MAEG; ORFNames=PP648, UNQ281/PRO320;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   EGFL7_HUMAN             Reviewed;         273 AA.
AC   Q9UHF1; B3KRP0; M9VTX9; Q5M7Y5; Q5VUD5; Q96EG0;
DE   RecName: Full=Epidermal growth factor-like protein 7;
DE            Short=EGF-like protein 7;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 7;
DE            Short=Multiple EGF-like domains protein 7;
DE   AltName: Full=NOTCH4-like protein;
DE   AltName: Full=Vascular endothelial statin;
DE            Short=VE-statin;
DE   AltName: Full=Zneu1;
DE   Flags: Precursor;
GN   Name=EGFL7; Synonyms=MEGF7; ORFNames=UNQ187/PRO1449;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001568; P:blood vessel development; ISS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IMP:MGI.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:MGI.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
//
ID   EGFL8_HUMAN             Reviewed;         293 AA.
AC   Q99944; B0S884; G5E9Q0; Q5JP23; Q5SSX3; Q8IV30;
DE   RecName: Full=Epidermal growth factor-like protein 8;
DE            Short=EGF-like protein 8;
DE   AltName: Full=Vascular endothelial statin-2;
DE            Short=VE-statin-2;
DE   Flags: Precursor;
GN   Name=EGFL8; Synonyms=C6orf8, NG3; ORFNames=UNQ8752/PRO29920;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   EGFLA_HUMAN             Reviewed;        1017 AA.
AC   Q63HQ2; A8K6D7; Q5U643; Q6P3V1; Q8N124; Q8N197; Q8N7Y0; Q8N8N5;
AC   Q8NAL2;
DE   RecName: Full=Pikachurin;
DE   AltName: Full=Agrin-like protein;
DE   AltName: Full=EGF-like, fibronectin type-III and laminin G-like domain-containing protein;
DE   Flags: Precursor;
GN   Name=EGFLAM; Synonyms=AGRINL, AGRNL;
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   EGFR_HUMAN              Reviewed;        1210 AA.
AC   P00533; O00688; O00732; P06268; Q14225; Q68GS5; Q92795; Q9BZS2;
AC   Q9GZX1; Q9H2C9; Q9H3C9; Q9UMD7; Q9UMD8; Q9UMG5;
DE   RecName: Full=Epidermal growth factor receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=Proto-oncogene c-ErbB-1;
DE   AltName: Full=Receptor tyrosine-protein kinase erbB-1;
DE   Flags: Precursor;
GN   Name=EGFR; Synonyms=ERBB, ERBB1, HER1;
DR   GuidetoPHARMACOLOGY; 1797; -.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005006; F:epidermal growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:MGI.
DR   GO; GO:0043006; P:activation of phospholipase A2 activity by calcium-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:UniProtKB.
DR   GO; GO:0019694; P:alkanesulfonate metabolic process; IEA:Ensembl.
DR   GO; GO:0048143; P:astrocyte activation; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:MGI.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IDA:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0016101; P:diterpenoid metabolic process; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0042743; P:hydrogen peroxide metabolic process; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; ISS:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0010960; P:magnesium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; NAS:GOC.
DR   GO; GO:0060571; P:morphogenesis of an epithelial fold; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; NAS:UniProtKB.
DR   GO; GO:0042698; P:ovulation cycle; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0005976; P:polysaccharide metabolic process; IEA:Ensembl.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0051205; P:protein insertion into membrane; TAS:UniProtKB.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0033590; P:response to cobalamin; IEA:Ensembl.
DR   GO; GO:0033594; P:response to hydroxyisoflavone; IEA:Ensembl.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
DR   GO; GO:0070141; P:response to UV-A; IDA:BHF-UCL.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; IEA:Ensembl.
//
ID   EGF_HUMAN               Reviewed;        1207 AA.
AC   P01133; B4DRK7; E7EVD2; E9PBF0; Q52LZ6;
DE   RecName: Full=Pro-epidermal growth factor;
DE            Short=EGF;
DE   Contains:
DE     RecName: Full=Epidermal growth factor;
DE     AltName: Full=Urogastrone;
DE   Flags: Precursor;
GN   Name=EGF;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; TAS:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030297; F:transmembrane receptor protein tyrosine kinase activator activity; TAS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; TAS:GOC.
DR   GO; GO:0001525; P:angiogenesis; IDA:HGNC.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0090370; P:negative regulation of cholesterol efflux; IEA:Ensembl.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051048; P:negative regulation of secretion; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0021940; P:positive regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; TAS:UniProtKB.
DR   GO; GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:HGNC.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:HGNC.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:HGNC.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0090279; P:regulation of calcium ion import; IDA:BHF-UCL.
DR   GO; GO:2000008; P:regulation of protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0007262; P:STAT protein import into nucleus; ISS:UniProtKB.
//
ID   EGLN1_HUMAN             Reviewed;         426 AA.
AC   Q9GZT9; Q8N3M8; Q9BZS8; Q9BZT0;
DE   RecName: Full=Egl nine homolog 1;
DE            EC=1.14.11.29;
DE   AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 2;
DE            Short=HIF-PH2;
DE            Short=HIF-prolyl hydroxylase 2;
DE            Short=HPH-2;
DE   AltName: Full=Prolyl hydroxylase domain-containing protein 2;
DE            Short=PHD2;
DE   AltName: Full=SM-20;
GN   Name=EGLN1; Synonyms=C1orf12; ORFNames=PNAS-118, PNAS-137;
DR   GO; GO:0019899; F:enzyme binding; ISS:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0031545; F:peptidyl-proline 4-dioxygenase activity; IDA:FlyBase.
DR   GO; GO:0031543; F:peptidyl-proline dioxygenase activity; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0030821; P:negative regulation of cAMP catabolic process; ISS:BHF-UCL.
DR   GO; GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; ISS:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:HGNC.
DR   GO; GO:0032364; P:oxygen homeostasis; IDA:HGNC.
DR   GO; GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:FlyBase.
DR   GO; GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IDA:HGNC.
DR   GO; GO:0071731; P:response to nitric oxide; IDA:UniProtKB.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
//
ID   EGLN2_HUMAN             Reviewed;         407 AA.
AC   Q96KS0; A8K5S0; Q8WWY4; Q9BV14;
DE   RecName: Full=Egl nine homolog 2;
DE            EC=1.14.11.29;
DE   AltName: Full=Estrogen-induced tag 6;
DE   AltName: Full=HPH-3;
DE   AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 1;
DE            Short=HIF-PH1;
DE            Short=HIF-prolyl hydroxylase 1;
DE            Short=HPH-1;
DE   AltName: Full=Prolyl hydroxylase domain-containing protein 1;
DE            Short=PHD1;
GN   Name=EGLN2; Synonyms=EIT6;
DR   GO; GO:0008198; F:ferrous iron binding; NAS:UniProtKB.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.
DR   GO; GO:0019826; F:oxygen sensor activity; IDA:UniProtKB.
DR   GO; GO:0031545; F:peptidyl-proline 4-dioxygenase activity; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:FlyBase.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IMP:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
//
ID   EGLN3_HUMAN             Reviewed;         239 AA.
AC   Q9H6Z9; Q2TA79; Q3B8N4; Q6P1R2;
DE   RecName: Full=Egl nine homolog 3;
DE            EC=1.14.11.29;
DE   AltName: Full=HPH-1;
DE   AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 3;
DE            Short=HIF-PH3;
DE            Short=HIF-prolyl hydroxylase 3;
DE            Short=HPH-3;
DE   AltName: Full=Prolyl hydroxylase domain-containing protein 3;
DE            Short=PHD3;
GN   Name=EGLN3;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0031545; F:peptidyl-proline 4-dioxygenase activity; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:FlyBase.
DR   GO; GO:0018126; P:protein hydroxylation; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEP:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
//
ID   EGLN_HUMAN              Reviewed;         658 AA.
AC   P17813; Q14248; Q14926; Q5T9C0;
DE   RecName: Full=Endoglin;
DE   AltName: CD_antigen=CD105;
DE   Flags: Precursor;
GN   Name=ENG; Synonyms=END;
DR   GO; GO:0048185; F:activin binding; TAS:BHF-UCL.
DR   GO; GO:0005534; F:galactose binding; IDA:BHF-UCL.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IPI:BHF-UCL.
DR   GO; GO:0005072; F:transforming growth factor beta receptor, cytoplasmic mediator activity; IDA:BHF-UCL.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; IPI:BHF-UCL.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IMP:BHF-UCL.
DR   GO; GO:0003273; P:cell migration involved in endocardial cushion formation; IEA:Ensembl.
DR   GO; GO:0048870; P:cell motility; IMP:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0022009; P:central nervous system vasculogenesis; IMP:BHF-UCL.
DR   GO; GO:0001300; P:chronological cell aging; IEA:Ensembl.
DR   GO; GO:0070483; P:detection of hypoxia; IDA:BHF-UCL.
DR   GO; GO:0070278; P:extracellular matrix constituent secretion; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; IMP:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:GOC.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; IMP:BHF-UCL.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:BHF-UCL.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030155; P:regulation of cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0042325; P:regulation of phosphorylation; TAS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:HGNC.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0036273; P:response to statin; IEA:Ensembl.
DR   GO; GO:0071559; P:response to transforming growth factor beta; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; IMP:BHF-UCL.
DR   GO; GO:0048845; P:venous blood vessel morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; IMP:BHF-UCL.
//
ID   EGR1_HUMAN              Reviewed;         543 AA.
AC   P18146;
DE   RecName: Full=Early growth response protein 1;
DE            Short=EGR-1;
DE   AltName: Full=AT225;
DE   AltName: Full=Nerve growth factor-induced protein A;
DE            Short=NGFI-A;
DE   AltName: Full=Transcription factor ETR103;
DE   AltName: Full=Transcription factor Zif268;
DE   AltName: Full=Zinc finger protein 225;
DE   AltName: Full=Zinc finger protein Krox-24;
GN   Name=EGR1; Synonyms=KROX24, ZNF225;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IBA:RefGenome.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IBA:RefGenome.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071504; P:cellular response to heparin; ISS:UniProtKB.
DR   GO; GO:0071455; P:cellular response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0071317; P:cellular response to isoquinoline alkaloid; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IBA:RefGenome.
DR   GO; GO:0033233; P:regulation of protein sumoylation; IDA:BHF-UCL.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0034465; P:response to carbon monoxide; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0071873; P:response to norepinephrine; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IBA:RefGenome.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   EGR2_HUMAN              Reviewed;         476 AA.
AC   P11161; B2R724; B3KRD7; Q68CZ5; Q8IV26; Q9UNA6;
DE   RecName: Full=E3 SUMO-protein ligase EGR2;
DE            EC=6.3.2.-;
DE   AltName: Full=AT591;
DE   AltName: Full=Early growth response protein 2;
DE            Short=EGR-2;
DE   AltName: Full=Zinc finger protein Krox-20;
GN   Name=EGR2; Synonyms=KROX20;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0035284; P:brain segmentation; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071320; P:cellular response to cAMP; IBA:RefGenome.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IBA:RefGenome.
DR   GO; GO:0021612; P:facial nerve structural organization; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006611; P:protein export from nucleus; ISS:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IBA:RefGenome.
DR   GO; GO:0030278; P:regulation of ossification; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0021660; P:rhombomere 3 formation; IEA:Ensembl.
DR   GO; GO:0021666; P:rhombomere 5 formation; IEA:Ensembl.
DR   GO; GO:0007622; P:rhythmic behavior; IEA:Ensembl.
DR   GO; GO:0014037; P:Schwann cell differentiation; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   EGR3_HUMAN              Reviewed;         387 AA.
AC   Q06889; A8K8U9; B4DHJ5; E7EW38; Q2M3W2;
DE   RecName: Full=Early growth response protein 3;
DE            Short=EGR-3;
DE   AltName: Full=Zinc finger protein pilot;
GN   Name=EGR3; Synonyms=PILOT;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0071320; P:cellular response to cAMP; IBA:RefGenome.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IBA:RefGenome.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EGR4_HUMAN              Reviewed;         589 AA.
AC   Q05215; B2RAE3; G3V1T5; Q2Z1P5;
DE   RecName: Full=Early growth response protein 4;
DE            Short=EGR-4;
DE   AltName: Full=AT133;
GN   Name=EGR4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0071320; P:cellular response to cAMP; IBA:RefGenome.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EH1L1_HUMAN             Reviewed;        1523 AA.
AC   Q8N3D4; Q8TB89; Q9H7M7;
DE   RecName: Full=EH domain-binding protein 1-like protein 1;
GN   Name=EHBP1L1;
//
ID   EHBP1_HUMAN             Reviewed;        1231 AA.
AC   Q8NDI1; O94977; Q53TG7; Q53TV6; Q580X2; Q6NX72; Q6PIT3; Q6QNV2;
AC   Q9NWI9;
DE   RecName: Full=EH domain-binding protein 1;
GN   Name=EHBP1; Synonyms=KIAA0903, NACSIN;
//
ID   EHD1_HUMAN              Reviewed;         534 AA.
AC   Q9H4M9; O14611; Q2M3Q4; Q9UNR3;
DE   RecName: Full=EH domain-containing protein 1;
DE   AltName: Full=PAST homolog 1;
DE            Short=hPAST1;
DE   AltName: Full=Testilin;
GN   Name=EHD1; Synonyms=PAST, PAST1; ORFNames=CDABP0131;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0032456; P:endocytic recycling; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; ISS:BHF-UCL.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; ISS:BHF-UCL.
DR   GO; GO:2001137; P:positive regulation of endocytic recycling; ISS:UniProtKB.
DR   GO; GO:1901741; P:positive regulation of myoblast fusion; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
//
ID   EHD2_HUMAN              Reviewed;         543 AA.
AC   Q9NZN4; B2RDH9; Q96CB6;
DE   RecName: Full=EH domain-containing protein 2;
DE   AltName: Full=PAST homolog 2;
GN   Name=EHD2; Synonyms=PAST2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0032456; P:endocytic recycling; IGI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:2001137; P:positive regulation of endocytic recycling; ISS:UniProtKB.
DR   GO; GO:1901741; P:positive regulation of myoblast fusion; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
//
ID   EHD3_HUMAN              Reviewed;         535 AA.
AC   Q9NZN3; D6W574; Q8N514; Q9NZB3;
DE   RecName: Full=EH domain-containing protein 3;
DE   AltName: Full=PAST homolog 3;
GN   Name=EHD3; Synonyms=EHD2, PAST3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0032456; P:endocytic recycling; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IGI:MGI.
DR   GO; GO:0086036; P:regulation of cardiac muscle cell membrane potential; IGI:MGI.
//
ID   EHF_HUMAN               Reviewed;         300 AA.
AC   Q9NZC4; D3DR08; D3DR10; E9PSB2; Q9H509; Q9UKF9; Q9Y5V4; Q9Y5V5;
DE   RecName: Full=ETS homologous factor;
DE            Short=hEHF;
DE   AltName: Full=ETS domain-containing transcription factor;
DE   AltName: Full=Epithelium-specific Ets transcription factor 3;
DE            Short=ESE-3;
GN   Name=EHF; Synonyms=ESE3, ESE3B, ESEJ;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   EHD4_HUMAN              Reviewed;         541 AA.
AC   Q9H223; Q9HAR1; Q9NZN2;
DE   RecName: Full=EH domain-containing protein 4;
DE   AltName: Full=Hepatocellular carcinoma-associated protein 10/11;
DE   AltName: Full=PAST homolog 4;
GN   Name=EHD4; Synonyms=HCA10, HCA11, PAST4; ORFNames=FKSG7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0032456; P:endocytic recycling; IGI:UniProtKB.
DR   GO; GO:0006907; P:pinocytosis; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
//
ID   EHMT1_HUMAN             Reviewed;        1298 AA.
AC   Q9H9B1; B1AQ58; B1AQ59; Q86X08; Q8TCN7; Q96F53; Q96JF1; Q96KH4;
DE   RecName: Full=Histone-lysine N-methyltransferase EHMT1;
DE            EC=2.1.1.-;
DE            EC=2.1.1.43;
DE   AltName: Full=Euchromatic histone-lysine N-methyltransferase 1;
DE            Short=Eu-HMTase1;
DE   AltName: Full=G9a-like protein 1;
DE            Short=GLP;
DE            Short=GLP1;
DE   AltName: Full=Histone H3-K9 methyltransferase 5;
DE            Short=H3-K9-HMTase 5;
DE   AltName: Full=Lysine N-methyltransferase 1D;
GN   Name=EHMT1; Synonyms=EUHMTASE1, GLP, KIAA1876, KMT1D;
DR   GuidetoPHARMACOLOGY; 2651; -.
DR   GO; GO:0046976; F:histone methyltransferase activity (H3-K27 specific); ISS:UniProtKB.
DR   GO; GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008168; F:methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IDA:UniProtKB.
DR   GO; GO:0006306; P:DNA methylation; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0016571; P:histone methylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.
DR   GO; GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.
//
ID   EHMT2_HUMAN             Reviewed;        1210 AA.
AC   Q96KQ7; B0UZY2; Q14349; Q5JP83; Q5JQ92; Q5JQA1; Q5JQG3; Q6PK06;
AC   Q96MH5; Q96QD0; Q9UQL8; Q9Y331;
DE   RecName: Full=Histone-lysine N-methyltransferase EHMT2;
DE            EC=2.1.1.-;
DE            EC=2.1.1.43;
DE   AltName: Full=Euchromatic histone-lysine N-methyltransferase 2;
DE   AltName: Full=HLA-B-associated transcript 8;
DE   AltName: Full=Histone H3-K9 methyltransferase 3;
DE            Short=H3-K9-HMTase 3;
DE   AltName: Full=Lysine N-methyltransferase 1C;
DE   AltName: Full=Protein G9a;
GN   Name=EHMT2; Synonyms=BAT8, C6orf30, G9A, KMT1C, NG36;
DR   GuidetoPHARMACOLOGY; 2652; -.
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProt.
DR   GO; GO:0046976; F:histone methyltransferase activity (H3-K27 specific); ISS:UniProtKB.
DR   GO; GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; ISS:UniProtKB.
DR   GO; GO:0010424; P:DNA methylation on cytosine within a CG sequence; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0016571; P:histone methylation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; IMP:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007130; P:synaptonemal complex assembly; IEA:Ensembl.
//
ID   EI24_HUMAN              Reviewed;         340 AA.
AC   O14681; A8K7D6; Q9BUQ1;
DE   RecName: Full=Etoposide-induced protein 2.4 homolog;
DE   AltName: Full=p53-induced gene 8 protein;
GN   Name=EI24; Synonyms=PIG8;
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:MGI.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   EI2BA_HUMAN             Reviewed;         305 AA.
AC   Q14232; A6NLY9; Q3SXP4;
DE   RecName: Full=Translation initiation factor eIF-2B subunit alpha;
DE   AltName: Full=eIF-2B GDP-GTP exchange factor subunit alpha;
GN   Name=EIF2B1; Synonyms=EIF2BA;
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:Ensembl.
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0032057; P:negative regulation of translational initiation in response to stress; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
DR   GO; GO:0009749; P:response to glucose; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EI2BB_HUMAN             Reviewed;         351 AA.
AC   P49770; O43201;
DE   RecName: Full=Translation initiation factor eIF-2B subunit beta;
DE   AltName: Full=S20I15;
DE   AltName: Full=S20III15;
DE   AltName: Full=eIF-2B GDP-GTP exchange factor subunit beta;
GN   Name=EIF2B2; Synonyms=EIF2BB;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042552; P:myelination; IMP:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.
DR   GO; GO:0009749; P:response to glucose; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EI2BD_HUMAN             Reviewed;         523 AA.
AC   Q9UI10; Q53RY7; Q5BJF4; Q9BUV9; Q9UBG4; Q9UIQ9; Q9UJ95;
DE   RecName: Full=Translation initiation factor eIF-2B subunit delta;
DE   AltName: Full=eIF-2B GDP-GTP exchange factor subunit delta;
GN   Name=EIF2B4; Synonyms=EIF2BD;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0031369; F:translation initiation factor binding; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042552; P:myelination; IMP:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IBA:RefGenome.
DR   GO; GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0006417; P:regulation of translation; NAS:UniProtKB.
DR   GO; GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
DR   GO; GO:0009749; P:response to glucose; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EI2BE_HUMAN             Reviewed;         721 AA.
AC   Q13144; Q541Z1; Q96D04;
DE   RecName: Full=Translation initiation factor eIF-2B subunit epsilon;
DE   AltName: Full=eIF-2B GDP-GTP exchange factor subunit epsilon;
GN   Name=EIF2B5; Synonyms=EIF2BE;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.
DR   GO; GO:0031369; F:translation initiation factor binding; ISS:UniProtKB.
DR   GO; GO:0014002; P:astrocyte development; IMP:UniProtKB.
DR   GO; GO:0048708; P:astrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042552; P:myelination; IMP:UniProtKB.
DR   GO; GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IMP:UniProtKB.
DR   GO; GO:0045948; P:positive regulation of translational initiation; ISS:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:UniProtKB.
DR   GO; GO:0009749; P:response to glucose; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; IMP:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EI2BG_HUMAN             Reviewed;         452 AA.
AC   Q9NR50; B2RBH8; D3DPZ2; Q5QP89; Q5QP90; Q8NDB5; Q8WV57; Q9H850;
DE   RecName: Full=Translation initiation factor eIF-2B subunit gamma;
DE   AltName: Full=eIF-2B GDP-GTP exchange factor subunit gamma;
GN   Name=EIF2B3;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0009749; P:response to glucose; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EID2B_HUMAN             Reviewed;         161 AA.
AC   Q96D98; Q8N8S0;
DE   RecName: Full=EP300-interacting inhibitor of differentiation 2B;
DE            Short=EID-2B;
DE   AltName: Full=EID-2-like inhibitor of differentiation 3;
DE            Short=EID-3;
GN   Name=EID2B; Synonyms=EID3;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EID2_HUMAN              Reviewed;         236 AA.
AC   Q8N6I1; A7YQ71; Q6X7T0; Q6ZR61;
DE   RecName: Full=EP300-interacting inhibitor of differentiation 2;
DE            Short=EID-2;
DE   AltName: Full=CREBBP/EP300 inhibitor 2;
DE   AltName: Full=EID-1-like inhibitor of differentiation 2;
GN   Name=EID2; Synonyms=CRI2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046332; F:SMAD binding; IDA:HGNC.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:HGNC.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007181; P:transforming growth factor beta receptor complex assembly; IDA:HGNC.
//
ID   EID1_HUMAN              Reviewed;         187 AA.
AC   Q9Y6B2; B2RD11; Q8N7I4; Q9BZT9;
DE   RecName: Full=EP300-interacting inhibitor of differentiation 1;
DE   AltName: Full=21 kDa pRb-associated protein;
DE   AltName: Full=CREBBP/EP300 inhibitory protein 1;
DE   AltName: Full=E1A-like inhibitor of differentiation 1;
DE            Short=EID-1;
GN   Name=EID1; Synonyms=C15orf3, CRI1, RBP21; ORFNames=PNAS-22, PTD014;
DR   GO; GO:0035035; F:histone acetyltransferase binding; IDA:UniProtKB.
DR   GO; GO:0035034; F:histone acetyltransferase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035065; P:regulation of histone acetylation; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EID3_HUMAN              Reviewed;         333 AA.
AC   Q8N140;
DE   RecName: Full=EP300-interacting inhibitor of differentiation 3;
DE            Short=EID-3;
DE   AltName: Full=E1A-like inhibitor of differentiation 3;
DE   AltName: Full=EID-1-like inhibitor of differentiation 3;
DE   AltName: Full=Non-structural maintenance of chromosomes element 4 homolog B;
DE            Short=NS4EB;
DE            Short=Non-SMC element 4 homolog B;
GN   Name=EID3;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EIF1A_HUMAN             Reviewed;         165 AA.
AC   Q8N9N8; B2R4N5; Q9BSC1;
DE   RecName: Full=Probable RNA-binding protein EIF1AD;
DE   AltName: Full=Eukaryotic translation initiation factor 1A domain-containing protein;
DE   AltName: Full=Haponin;
GN   Name=EIF1AD;
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
//
ID   EIF1B_HUMAN             Reviewed;         113 AA.
AC   O60739; Q9UQF8;
DE   RecName: Full=Eukaryotic translation initiation factor 1b;
DE            Short=eIF1b;
DE   AltName: Full=Protein translation factor SUI1 homolog GC20;
GN   Name=EIF1B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006446; P:regulation of translational initiation; NAS:UniProtKB.
//
ID   EIF1_HUMAN              Reviewed;         113 AA.
AC   P41567; Q9UNQ9;
DE   RecName: Full=Eukaryotic translation initiation factor 1;
DE            Short=eIF1;
DE   AltName: Full=A121;
DE   AltName: Full=Protein translation factor SUI1 homolog;
DE   AltName: Full=Sui1iso1;
GN   Name=EIF1; Synonyms=SUI1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.
DR   GO; GO:0009048; P:dosage compensation by inactivation of X chromosome; IEA:Ensembl.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   EIF2A_HUMAN             Reviewed;         585 AA.
AC   Q9BY44; A8MPS6; D3DNI9; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81;
DE   RecName: Full=Eukaryotic translation initiation factor 2A;
DE            Short=eIF-2A;
DE   AltName: Full=65 kDa eukaryotic translation initiation factor 2A;
DE   Contains:
DE     RecName: Full=Eukaryotic translation initiation factor 2A, N-terminally processed;
GN   Name=EIF2A; ORFNames=CDA02, MSTP004, MSTP089;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IMP:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IMP:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IMP:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IMP:UniProtKB.
DR   GO; GO:0042255; P:ribosome assembly; IMP:UniProtKB.
DR   GO; GO:0032933; P:SREBP signaling pathway; IEA:Ensembl.
//
ID   EIF2D_HUMAN             Reviewed;         584 AA.
AC   P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18;
AC   Q9NZ21;
DE   RecName: Full=Eukaryotic translation initiation factor 2D;
DE            Short=eIF2d;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 56;
DE   AltName: Full=Ligatin;
GN   Name=EIF2D; Synonyms=HCA56, LGTN;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
//
ID   EIF3A_HUMAN             Reviewed;        1382 AA.
AC   Q14152; B1AMV5; O00653; Q15778;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit A;
DE            Short=eIF3a;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 10;
DE   AltName: Full=eIF-3-theta;
DE   AltName: Full=eIF3 p167;
DE   AltName: Full=eIF3 p180;
DE   AltName: Full=eIF3 p185;
GN   Name=EIF3A; Synonyms=EIF3S10, KIAA0139;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001732; P:formation of translation initiation complex; IDA:UniProtKB.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IC:UniProtKB.
//
ID   EIF3B_HUMAN             Reviewed;         814 AA.
AC   P55884; A4D208; Q2NL77; Q9UMF9;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit B;
DE            Short=eIF3b;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 9;
DE   AltName: Full=Prt1 homolog;
DE            Short=hPrt1;
DE   AltName: Full=eIF-3-eta;
DE   AltName: Full=eIF3 p110;
DE   AltName: Full=eIF3 p116;
GN   Name=EIF3B; Synonyms=EIF3S9;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; TAS:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3C_HUMAN             Reviewed;         913 AA.
AC   Q99613; A8K7Z0; B2RXG3; O00215; Q9BW98;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit C;
DE            Short=eIF3c;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 8;
DE   AltName: Full=eIF3 p110;
GN   Name=EIF3C; Synonyms=EIF3S8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3D_HUMAN             Reviewed;         548 AA.
AC   O15371; B2R7D4; Q3MJD9; Q5M9Q6;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit D;
DE            Short=eIF3d;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 7;
DE   AltName: Full=eIF-3-zeta;
DE   AltName: Full=eIF3 p66;
GN   Name=EIF3D; Synonyms=EIF3S7;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001732; P:formation of translation initiation complex; IEA:Ensembl.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3E_HUMAN             Reviewed;         445 AA.
AC   P60228; O43902; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit E;
DE            Short=eIF3e;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 6;
DE   AltName: Full=Viral integration site protein INT-6 homolog;
DE   AltName: Full=eIF-3 p48;
GN   Name=EIF3E; Synonyms=EIF3S6, INT6;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IC:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045947; P:negative regulation of translational initiation; NAS:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0006446; P:regulation of translational initiation; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3F_HUMAN             Reviewed;         357 AA.
AC   O00303; A8K0S2; Q6IB45; Q8N978;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit F;
DE            Short=eIF3f;
DE   AltName: Full=Deubiquitinating enzyme eIF3f;
DE            EC=3.4.19.12;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 5;
DE   AltName: Full=eIF-3-epsilon;
DE   AltName: Full=eIF3 p47;
GN   Name=EIF3F; Synonyms=EIF3S5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; TAS:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3G_HUMAN             Reviewed;         320 AA.
AC   O75821; O14801; Q969U5;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit G;
DE            Short=eIF3g;
DE   AltName: Full=Eukaryotic translation initiation factor 3 RNA-binding subunit;
DE            Short=eIF-3 RNA-binding subunit;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 4;
DE   AltName: Full=eIF-3-delta;
DE   AltName: Full=eIF3 p42;
DE   AltName: Full=eIF3 p44;
GN   Name=EIF3G; Synonyms=EIF3S4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3H_HUMAN             Reviewed;         352 AA.
AC   O15372;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit H;
DE            Short=eIF3h;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 3;
DE   AltName: Full=eIF-3-gamma;
DE   AltName: Full=eIF3 p40 subunit;
GN   Name=EIF3H; Synonyms=EIF3S3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3I_HUMAN             Reviewed;         325 AA.
AC   Q13347;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit I;
DE            Short=eIF3i;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 2;
DE   AltName: Full=TGF-beta receptor-interacting protein 1;
DE            Short=TRIP-1;
DE   AltName: Full=eIF-3-beta;
DE   AltName: Full=eIF3 p36;
GN   Name=EIF3I; Synonyms=EIF3S2, TRIP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3J_HUMAN             Reviewed;         258 AA.
AC   O75822; B4DUI3; F5H425; Q9BUD2; Q9H8Q2; Q9UI65;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit J;
DE            Short=eIF3j;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 1;
DE   AltName: Full=eIF-3-alpha;
DE   AltName: Full=eIF3 p35;
GN   Name=EIF3J; Synonyms=EIF3S1; ORFNames=PRO0391;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IC:UniProtKB.
//
ID   EIF3K_HUMAN             Reviewed;         218 AA.
AC   Q9UBQ5; A8K0I9; Q96IQ0; Q9Y6D1;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit K;
DE            Short=eIF3k;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 12;
DE   AltName: Full=Muscle-specific gene M9 protein;
DE   AltName: Full=PLAC-24;
DE   AltName: Full=eIF-3 p25;
DE   AltName: Full=eIF-3 p28;
GN   Name=EIF3K; Synonyms=EIF3S12;
GN   ORFNames=ARG134, HSPC029, MSTP001, PTD001;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3L_HUMAN             Reviewed;         564 AA.
AC   Q9Y262; B2RDG6; B4DYB2; G8JLH4; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15;
AC   Q6ICD2;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit L;
DE            Short=eIF3l;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit 6-interacting protein;
DE   AltName: Full=Eukaryotic translation initiation factor 3 subunit E-interacting protein;
GN   Name=EIF3L; Synonyms=EIF3EIP, EIF3S6IP;
GN   ORFNames=HSPC021, HSPC025, MSTP005;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   EIF3M_HUMAN             Reviewed;         374 AA.
AC   Q7L2H7; A8K7X4; O60735; Q2F836; Q53HL6; Q9BXW1;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit M;
DE            Short=eIF3m;
DE   AltName: Full=Fetal lung protein B5;
DE            Short=hFL-B5;
DE   AltName: Full=PCI domain-containing protein 1;
GN   Name=EIF3M; Synonyms=HFLB5, PCID1; ORFNames=GA17, PNAS-125;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0002183; P:cytoplasmic translational initiation; IBA:RefGenome.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006413; P:translational initiation; IC:UniProtKB.
//
ID   EIFCL_HUMAN             Reviewed;         914 AA.
AC   B5ME19;
DE   RecName: Full=Eukaryotic translation initiation factor 3 subunit C-like protein;
GN   Name=EIF3CL;
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:UniProtKB-HAMAP.
//
ID   EKI1_HUMAN              Reviewed;         452 AA.
AC   Q9HBU6; G5E969;
DE   RecName: Full=Ethanolamine kinase 1;
DE            Short=EKI 1;
DE            EC=2.7.1.82;
GN   Name=ETNK1; Synonyms=EKI1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004305; F:ethanolamine kinase activity; IDA:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   EKI2_HUMAN              Reviewed;         386 AA.
AC   Q9NVF9; B7Z7K1; Q5SXX5; Q68CK3; Q96G05;
DE   RecName: Full=Ethanolamine kinase 2;
DE            Short=EKI 2;
DE            EC=2.7.1.82;
DE   AltName: Full=Ethanolamine kinase-like protein;
GN   Name=ETNK2; Synonyms=EKI2; ORFNames=HMFT1716;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004305; F:ethanolamine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ELAF_HUMAN              Reviewed;         117 AA.
AC   P19957; E1P618; Q6FG74;
DE   RecName: Full=Elafin;
DE   AltName: Full=Elastase-specific inhibitor;
DE            Short=ESI;
DE   AltName: Full=Peptidase inhibitor 3;
DE            Short=PI-3;
DE   AltName: Full=Protease inhibitor WAP3;
DE   AltName: Full=Skin-derived antileukoproteinase;
DE            Short=SKALP;
DE   AltName: Full=WAP four-disulfide core domain protein 14;
DE   Flags: Precursor;
GN   Name=PI3; Synonyms=WAP3, WFDC14;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0007620; P:copulation; IEA:InterPro.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   ELAV1_HUMAN             Reviewed;         326 AA.
AC   Q15717; Q53XN6; Q9BTT1;
DE   RecName: Full=ELAV-like protein 1;
DE   AltName: Full=Hu-antigen R;
DE            Short=HuR;
GN   Name=ELAVL1; Synonyms=HUR;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IDA:MGI.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0048255; P:mRNA stabilization; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:MGI.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   ELAV2_HUMAN             Reviewed;         359 AA.
AC   Q12926; D3DRK3; Q13235; Q59G15; Q8NEM4; Q9H1Q8;
DE   RecName: Full=ELAV-like protein 2;
DE   AltName: Full=ELAV-like neuronal protein 1;
DE   AltName: Full=Hu-antigen B;
DE            Short=HuB;
DE   AltName: Full=Nervous system-specific RNA-binding protein Hel-N1;
GN   Name=ELAVL2; Synonyms=HUB;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
//
ID   ELAV3_HUMAN             Reviewed;         367 AA.
AC   Q14576; Q16135; Q96CL8; Q96QS9;
DE   RecName: Full=ELAV-like protein 3;
DE   AltName: Full=Hu-antigen C;
DE            Short=HuC;
DE   AltName: Full=Paraneoplastic cerebellar degeneration-associated antigen;
DE   AltName: Full=Paraneoplastic limbic encephalitis antigen 21;
GN   Name=ELAVL3; Synonyms=HUC, PLE21;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   ELAV4_HUMAN             Reviewed;         380 AA.
AC   P26378; B1APY6; B1APY7; B7Z4G7; Q8IYD4; Q96J74; Q96J75; Q9UD24;
DE   RecName: Full=ELAV-like protein 4;
DE   AltName: Full=Hu-antigen D;
DE            Short=HuD;
DE   AltName: Full=Paraneoplastic encephalomyelitis antigen HuD;
GN   Name=ELAVL4; Synonyms=HUD, PNEM;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   ELA_HUMAN               Reviewed;          54 AA.
AC   P0DMC3;
DE   RecName: Full=Apelin receptor early endogenous ligand;
DE   AltName: Full=Protein Elabela;
DE   AltName: Full=Protein Toddler;
DE   Flags: Precursor;
GN   Name=APELA; Synonyms=ELA, TDL;
DR   GO; GO:0031704; F:apelin receptor binding; ISS:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR   GO; GO:0060183; P:apelin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0090134; P:cell migration involved in mesendoderm migration; ISS:UniProtKB.
DR   GO; GO:0007492; P:endoderm development; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0090133; P:mesendoderm migration; ISS:UniProtKB.
//
ID   ELF1_HUMAN              Reviewed;         619 AA.
AC   P32519; B4E2I5; E9PDQ9; Q8N6F6; Q9UDE1;
DE   RecName: Full=ETS-related transcription factor Elf-1;
DE   AltName: Full=E74-like factor 1;
GN   Name=ELF1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001817; P:regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ELF2_HUMAN              Reviewed;         593 AA.
AC   Q15723; Q15724; Q15725; Q6P1K5;
DE   RecName: Full=ETS-related transcription factor Elf-2;
DE   AltName: Full=E74-like factor 2;
DE   AltName: Full=New ETS-related factor;
GN   Name=ELF2; Synonyms=NERF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ELF3_HUMAN              Reviewed;         371 AA.
AC   P78545; B2R5Q6; Q6IAP8; Q7RU03; Q7Z3X2; Q8NFG2; Q99718;
DE   RecName: Full=ETS-related transcription factor Elf-3;
DE   AltName: Full=E74-like factor 3;
DE   AltName: Full=Epithelial-restricted with serine box;
DE   AltName: Full=Epithelium-restricted Ets protein ESX;
DE   AltName: Full=Epithelium-specific Ets transcription factor 1;
DE            Short=ESE-1;
GN   Name=ELF3; Synonyms=ERT, ESX, JEN;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEP:UniProtKB.
DR   GO; GO:0060056; P:mammary gland involution; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ELF4_HUMAN              Reviewed;         663 AA.
AC   Q99607; D3DTG1; O60435;
DE   RecName: Full=ETS-related transcription factor Elf-4;
DE   AltName: Full=E74-like factor 4;
DE   AltName: Full=Myeloid Elf-1-like factor;
GN   Name=ELF4; Synonyms=ELFR, MEF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0001787; P:natural killer cell proliferation; ISS:UniProtKB.
DR   GO; GO:0001866; P:NK T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ELF5_HUMAN              Reviewed;         265 AA.
AC   Q9UKW6; A6XAE6; A8K452; O95175; Q8N2K9; Q96QY3; Q9UKW5;
DE   RecName: Full=ETS-related transcription factor Elf-5;
DE   AltName: Full=E74-like factor 5;
DE   AltName: Full=Epithelium-restricted ESE-1-related Ets factor;
DE   AltName: Full=Epithelium-specific Ets transcription factor 2;
DE            Short=ESE-2;
GN   Name=ELF5; Synonyms=ESE2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ELFN1_HUMAN             Reviewed;         828 AA.
AC   P0C7U0; H3BS57;
DE   RecName: Full=Protein ELFN1;
DE   AltName: Full=Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 28;
DE   Flags: Precursor;
GN   Name=ELFN1; Synonyms=PPP1R28;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; ISS:UniProtKB.
//
ID   ELK1_HUMAN              Reviewed;         428 AA.
AC   P19419; B2R7H4; O75606; O95058; Q969X8; Q9UJM4;
DE   RecName: Full=ETS domain-containing protein Elk-1;
GN   Name=ELK1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   ELK3_HUMAN              Reviewed;         407 AA.
AC   P41970; B2R6S6; Q6FG57; Q6GU29; Q9UD17;
DE   RecName: Full=ETS domain-containing protein Elk-3;
DE   AltName: Full=ETS-related protein ERP;
DE   AltName: Full=ETS-related protein NET;
DE   AltName: Full=Serum response factor accessory protein 2;
DE            Short=SAP-2;
DE            Short=SRF accessory protein 2;
GN   Name=ELK3; Synonyms=NET, SAP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032422; F:purine-rich negative regulatory element binding; IDA:HGNC.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:HGNC.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   ELK4_HUMAN              Reviewed;         431 AA.
AC   P28324; P28323; Q6GSJ2;
DE   RecName: Full=ETS domain-containing protein Elk-4;
DE   AltName: Full=Serum response factor accessory protein 1;
DE            Short=SAP-1;
DE            Short=SRF accessory protein 1;
GN   Name=ELK4; Synonyms=SAP1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; TAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ELL2_HUMAN              Reviewed;         640 AA.
AC   O00472;
DE   RecName: Full=RNA polymerase II elongation factor ELL2;
GN   Name=ELL2;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ELL3_HUMAN              Reviewed;         397 AA.
AC   Q9HB65; B3KQ66; B3KX08; Q6I9Z7; Q9H634;
DE   RecName: Full=RNA polymerase II elongation factor ELL3;
GN   Name=ELL3;
DR   GO; GO:0035326; F:enhancer binding; ISS:UniProtKB.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   ELL_HUMAN               Reviewed;         621 AA.
AC   P55199;
DE   RecName: Full=RNA polymerase II elongation factor ELL;
DE   AltName: Full=Eleven-nineteen lysine-rich leukemia protein;
GN   Name=ELL; Synonyms=C19orf17;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; TAS:ProtInc.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ELMD1_HUMAN             Reviewed;         334 AA.
AC   Q8N336; B4E167; G5E9S5; Q9NPW3;
DE   RecName: Full=ELMO domain-containing protein 1;
GN   Name=ELMOD1;
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
//
ID   ELMD2_HUMAN             Reviewed;         293 AA.
AC   Q8IZ81; B2R712; D3DNZ0;
DE   RecName: Full=ELMO domain-containing protein 2;
GN   Name=ELMOD2;
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006909; P:phagocytosis; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.
//
ID   ELMO1_HUMAN             Reviewed;         727 AA.
AC   Q92556; A4D1X6; Q29R79; Q6ZTJ0; Q96PB0; Q9H0I1;
DE   RecName: Full=Engulfment and cell motility protein 1;
DE   AltName: Full=Protein ced-12 homolog;
GN   Name=ELMO1; Synonyms=KIAA0281;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IGI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; IGI:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IGI:UniProtKB.
DR   GO; GO:0016601; P:Rac protein signal transduction; IGI:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ELMD3_HUMAN             Reviewed;         381 AA.
AC   Q96FG2; B8ZZD6; D6W5K4; Q2M1K3; Q2XSU3; Q2XSU4; Q8NAC1; Q8TCK4;
AC   Q8WV70; Q8WY75; Q9H6Q8;
DE   RecName: Full=ELMO domain-containing protein 3;
DE   AltName: Full=RNA-binding motif and ELMO domain-containing protein 1;
DE   AltName: Full=RNA-binding motif protein 29;
DE   AltName: Full=RNA-binding protein 29;
GN   Name=ELMOD3; Synonyms=RBED1, RBM29; ORFNames=PP4068;
DR   GO; GO:0006909; P:phagocytosis; IEA:InterPro.
//
ID   ELMO2_HUMAN             Reviewed;         720 AA.
AC   Q96JJ3; E1P5T3; Q5JVZ6; Q96CJ2; Q96ME5; Q96PA9; Q9H938; Q9H9L5;
AC   Q9HAH0; Q9NQQ6;
DE   RecName: Full=Engulfment and cell motility protein 2;
DE   AltName: Full=Protein ced-12 homolog A;
DE            Short=hCed-12A;
GN   Name=ELMO2; Synonyms=CED12A, KIAA1834;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   ELMO3_HUMAN             Reviewed;         720 AA.
AC   Q96BJ8; B4DV86; Q9H8A5;
DE   RecName: Full=Engulfment and cell motility protein 3;
GN   Name=ELMO3;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
//
ID   ELNE_HUMAN              Reviewed;         267 AA.
AC   P08246; P09649; Q6B0D9; Q6LDP5;
DE   RecName: Full=Neutrophil elastase;
DE            EC=3.4.21.37;
DE   AltName: Full=Bone marrow serine protease;
DE   AltName: Full=Elastase-2;
DE   AltName: Full=Human leukocyte elastase;
DE            Short=HLE;
DE   AltName: Full=Medullasin;
DE   AltName: Full=PMN elastase;
DE   Flags: Precursor;
GN   Name=ELANE; Synonyms=ELA2;
DR   GuidetoPHARMACOLOGY; 2358; -.
DR   GO; GO:0019955; F:cytokine binding; IPI:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IMP:UniProt.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0002438; P:acute inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0045079; P:negative regulation of chemokine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050922; P:negative regulation of chemotaxis; NAS:UniProtKB.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; NAS:UniProtKB.
DR   GO; GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
DR   GO; GO:0070947; P:neutrophil mediated killing of fungus; IEA:Ensembl.
DR   GO; GO:0006909; P:phagocytosis; IEA:Ensembl.
DR   GO; GO:0050778; P:positive regulation of immune response; IEA:Ensembl.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; NAS:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:MGI.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0001878; P:response to yeast; IEA:Ensembl.
//
ID   ELN_HUMAN               Reviewed;         786 AA.
AC   P15502; B3KTS6; O15336; O15337; Q14233; Q14234; Q14235; Q14238;
AC   Q6P0L4; Q6ZWJ6; Q75MU5; Q7Z316; Q7Z3F5; Q9UMF5;
DE   RecName: Full=Elastin;
DE   AltName: Full=Tropoelastin;
DE   Flags: Precursor;
GN   Name=ELN;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0030023; F:extracellular matrix constituent conferring elasticity; IEA:Ensembl.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0043149; P:stress fiber assembly; IEA:Ensembl.
//
ID   ELOA3_HUMAN             Reviewed;         546 AA.
AC   Q8NG57;
DE   RecName: Full=RNA polymerase II transcription factor SIII subunit A3;
DE   AltName: Full=Elongin-A3;
DE            Short=EloA3;
DE   AltName: Full=Transcription elongation factor B polypeptide 3C;
GN   Name=TCEB3C; Synonyms=TCEB3L2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ELOA1_HUMAN             Reviewed;         798 AA.
AC   Q14241; B2R7Q8; Q8IXH1;
DE   RecName: Full=Transcription elongation factor B polypeptide 3;
DE   AltName: Full=Elongin 110 kDa subunit;
DE   AltName: Full=Elongin-A;
DE            Short=EloA;
DE   AltName: Full=RNA polymerase II transcription factor SIII subunit A1;
DE   AltName: Full=SIII p110;
GN   Name=TCEB3; ORFNames=MSTP059;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ELOB_HUMAN              Reviewed;         118 AA.
AC   Q15370; B7WPD3;
DE   RecName: Full=Transcription elongation factor B polypeptide 2;
DE   AltName: Full=Elongin 18 kDa subunit;
DE   AltName: Full=Elongin-B;
DE            Short=EloB;
DE   AltName: Full=RNA polymerase II transcription factor SIII subunit B;
DE   AltName: Full=SIII p18;
GN   Name=TCEB2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ELOA2_HUMAN             Reviewed;         753 AA.
AC   Q8IYF1; Q9P2V9;
DE   RecName: Full=RNA polymerase II transcription factor SIII subunit A2;
DE   AltName: Full=Elongin-A2;
DE            Short=EloA2;
DE   AltName: Full=Transcription elongation factor B polypeptide 3B;
GN   Name=TCEB3B; Synonyms=TCEB3L;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ELOC_HUMAN              Reviewed;         112 AA.
AC   Q15369; E5RGD9; Q567Q6;
DE   RecName: Full=Transcription elongation factor B polypeptide 1;
DE   AltName: Full=Elongin 15 kDa subunit;
DE   AltName: Full=Elongin-C;
DE            Short=EloC;
DE   AltName: Full=RNA polymerase II transcription factor SIII subunit C;
DE   AltName: Full=SIII p15;
GN   Name=TCEB1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ELOF1_HUMAN             Reviewed;          83 AA.
AC   P60002; Q8R1J7; Q96II4;
DE   RecName: Full=Transcription elongation factor 1 homolog;
GN   Name=ELOF1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ELOV2_HUMAN             Reviewed;         296 AA.
AC   Q9NXB9; Q6P9E1; Q86W94;
DE   RecName: Full=Elongation of very long chain fatty acids protein 2;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL2;
DE   AltName: Full=ELOVL fatty acid elongase 2;
DE            Short=ELOVL FA elongase 2;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 2;
GN   Name=ELOVL2; Synonyms=SSC2;
DR   GO; GO:0009922; F:fatty acid elongase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034626; P:fatty acid elongation, polyunsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; TAS:Reactome.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   ELOV1_HUMAN             Reviewed;         279 AA.
AC   Q9BW60; B4DP24; Q53HT2; Q5JUY3; Q8WXU3; Q9NVD9; Q9Y396;
DE   RecName: Full=Elongation of very long chain fatty acids protein 1;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL1;
DE   AltName: Full=ELOVL fatty acid elongase 1;
DE            Short=ELOVL FA elongase 1;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 1;
GN   Name=ELOVL1; Synonyms=SSC1; ORFNames=CGI-88;
DR   GO; GO:0009922; F:fatty acid elongase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034625; P:fatty acid elongation, monounsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0019367; P:fatty acid elongation, saturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   ELOV3_HUMAN             Reviewed;         270 AA.
AC   Q9HB03; Q5VZL3; Q8N180;
DE   RecName: Full=Elongation of very long chain fatty acids protein 3;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL3;
DE   AltName: Full=Cold-inducible glycoprotein of 30 kDa;
DE   AltName: Full=ELOVL fatty acid elongase 3;
DE            Short=ELOVL FA elongase 3;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 3;
GN   Name=ELOVL3; Synonyms=CIG30;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034625; P:fatty acid elongation, monounsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0034626; P:fatty acid elongation, polyunsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0019367; P:fatty acid elongation, saturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   ELOV4_HUMAN             Reviewed;         314 AA.
AC   Q9GZR5; B2R6B5; Q5TCS2; Q86YJ1; Q9H139;
DE   RecName: Full=Elongation of very long chain fatty acids protein 4;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL4;
DE   AltName: Full=ELOVL fatty acid elongase 4;
DE            Short=ELOVL FA elongase 4;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 4;
GN   Name=ELOVL4;
DR   GO; GO:0008020; F:G-protein coupled photoreceptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0009584; P:detection of visible light; NAS:GOC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0019367; P:fatty acid elongation, saturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   ELOV5_HUMAN             Reviewed;         299 AA.
AC   Q9NYP7; B4DZJ2; F6SH78; Q59EL3; Q5TGH5; Q6NXE7; Q7L2S5; Q8NCG4;
AC   Q9UI22;
DE   RecName: Full=Elongation of very long chain fatty acids protein 5;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL5;
DE   AltName: Full=ELOVL fatty acid elongase 5;
DE            Short=ELOVL FA elongase 5;
DE   AltName: Full=Fatty acid elongase 1;
DE            Short=hELO1;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 5;
GN   Name=ELOVL5; Synonyms=ELOVL2; ORFNames=PRO0530;
DR   GO; GO:0009922; F:fatty acid elongase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034625; P:fatty acid elongation, monounsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0034626; P:fatty acid elongation, polyunsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; TAS:Reactome.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   ELOV6_HUMAN             Reviewed;         265 AA.
AC   Q9H5J4; Q4W5L0; Q8NCD1;
DE   RecName: Full=Elongation of very long chain fatty acids protein 6;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL6;
DE   AltName: Full=ELOVL fatty acid elongase 6;
DE            Short=ELOVL FA elongase 6;
DE   AltName: Full=Fatty acid elongase 2;
DE            Short=hELO2;
DE   AltName: Full=Fatty acyl-CoA elongase;
DE   AltName: Full=Long-chain fatty-acyl elongase;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 6;
GN   Name=ELOVL6; Synonyms=FACE, LCE;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0019367; P:fatty acid elongation, saturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   ELOV7_HUMAN             Reviewed;         281 AA.
AC   A1L3X0; Q589T3; Q9H5D0; Q9NT66;
DE   RecName: Full=Elongation of very long chain fatty acids protein 7;
DE            EC=2.3.1.199;
DE   AltName: Full=3-keto acyl-CoA synthase ELOVL7;
DE   AltName: Full=ELOVL fatty acid elongase 7;
DE            Short=ELOVL FA elongase 7;
DE   AltName: Full=Very-long-chain 3-oxoacyl-CoA synthase 7;
GN   Name=ELOVL7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034626; P:fatty acid elongation, polyunsaturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0019367; P:fatty acid elongation, saturated fatty acid; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   ELP1_HUMAN              Reviewed;        1332 AA.
AC   O95163; Q5JSV2; Q9H327; Q9UG87;
DE   RecName: Full=Elongator complex protein 1;
DE            Short=ELP1;
DE   AltName: Full=IkappaB kinase complex-associated protein;
DE            Short=IKK complex-associated protein;
DE   AltName: Full=p150;
GN   Name=IKBKAP; Synonyms=ELP1, IKAP;
DR   GO; GO:0008607; F:phosphorylase kinase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:HGNC.
//
ID   ELP2_HUMAN              Reviewed;         826 AA.
AC   Q6IA86; A8KAI6; B4DTG0; B4DXP0; E7EP23; E9PCX0; Q53GZ0; Q687Y8;
AC   Q8N5C2; Q96GV4; Q96PI7; Q9H9N0; Q9NV81;
DE   RecName: Full=Elongator complex protein 2;
DE            Short=ELP2;
DE   AltName: Full=SHINC-2;
DE   AltName: Full=STAT3-interacting protein 1;
DE            Short=StIP1;
GN   Name=ELP2; Synonyms=STATIP1;
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0046425; P:regulation of JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:HGNC.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IC:HGNC.
//
ID   ELP3_HUMAN              Reviewed;         547 AA.
AC   Q9H9T3; Q53G84; Q6AWB0; Q9BVF7; Q9NVZ1;
DE   RecName: Full=Elongator complex protein 3;
DE            Short=hELP3;
DE            EC=2.3.1.48;
GN   Name=ELP3;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008607; F:phosphorylase kinase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:HGNC.
//
ID   ELP4_HUMAN              Reviewed;         424 AA.
AC   Q96EB1; B4E3W0; E7EPZ6; Q9H4E8; Q9NX11;
DE   RecName: Full=Elongator complex protein 4;
DE            Short=hELP4;
DE   AltName: Full=PAX6 neighbor gene protein;
GN   Name=ELP4; Synonyms=C11orf19, PAXNEB;
DR   GO; GO:0008607; F:phosphorylase kinase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; IDA:GOC.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IC:HGNC.
//
ID   ELP6_HUMAN              Reviewed;         266 AA.
AC   Q0PNE2; Q9BW57; Q9NXJ3;
DE   RecName: Full=Elongator complex protein 6;
DE   AltName: Full=Angiotonin-transactivated protein 1;
DE   AltName: Full=Protein TMEM103;
GN   Name=ELP6; Synonyms=ATP1, C3orf75, TMEM103;
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ELP5_HUMAN              Reviewed;         316 AA.
AC   Q8TE02; A8K1M5; D3DTN9; Q659B6; Q7Z2T4; Q8TDR9; Q9BUB2; Q9Y2Q4;
DE   RecName: Full=Elongator complex protein 5;
DE   AltName: Full=Dermal papilla-derived protein 6;
DE   AltName: Full=S-phase 2 protein;
GN   Name=ELP5; Synonyms=C17orf81, DERP6; ORFNames=HSPC002, MSTP071;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ELTD1_HUMAN             Reviewed;         690 AA.
AC   Q9HBW9; B1AR71; Q5KU34;
DE   RecName: Full=EGF, latrophilin and seven transmembrane domain-containing protein 1;
DE   AltName: Full=EGF-TM7-latrophilin-related protein;
DE            Short=ETL protein;
DE   Flags: Precursor;
GN   Name=ELTD1; Synonyms=ETL; ORFNames=UNQ202/PRO228;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   ELYS_HUMAN              Reviewed;        2266 AA.
AC   Q8WYP5; A6NGM0; A8MSG9; A8MZ86; Q7Z4E3; Q8IZA4; Q96EH9; Q9Y4Q6;
DE   RecName: Full=Protein ELYS;
DE   AltName: Full=Embryonic large molecule derived from yolk sac;
DE   AltName: Full=Protein MEL-28;
DE   AltName: Full=Putative AT-hook-containing transcription factor 1;
GN   Name=AHCTF1; Synonyms=ELYS, TMBS62; ORFNames=MSTP108;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   EM55_HUMAN              Reviewed;         466 AA.
AC   Q00013; B4DZV5; G3XAI1; Q2TSB6; Q5J7V5;
DE   RecName: Full=55 kDa erythrocyte membrane protein;
DE            Short=p55;
DE   AltName: Full=Membrane protein, palmitoylated 1;
GN   Name=MPP1; Synonyms=DXS552E, EMP55;
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   EMAL1_HUMAN             Reviewed;         815 AA.
AC   O00423; Q86U15; Q8N536; Q8N5C4; Q8WWL6;
DE   RecName: Full=Echinoderm microtubule-associated protein-like 1;
DE            Short=EMAP-1;
DE            Short=HuEMAP-1;
GN   Name=EML1; Synonyms=EMAP1, EMAPL, EMAPL1;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   EMAL2_HUMAN             Reviewed;         649 AA.
AC   O95834; B7Z3I2; B7Z3Q9; K7ERL7; Q59EN8; Q8N5A2; Q9UG50;
DE   RecName: Full=Echinoderm microtubule-associated protein-like 2;
DE            Short=EMAP-2;
DE            Short=HuEMAP-2;
GN   Name=EML2; Synonyms=EMAP2, EMAPL2;
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   EMAL3_HUMAN             Reviewed;         896 AA.
AC   Q32P44; Q6ZQW7; Q8NA55;
DE   RecName: Full=Echinoderm microtubule-associated protein-like 3;
DE            Short=EMAP-3;
GN   Name=EML3;
//
ID   EMAL4_HUMAN             Reviewed;         981 AA.
AC   Q9HC35; A6H8Y6; B2RBK3; B2RTW7; B5MCW9; Q3SWW0; Q53R29; Q53TW8;
AC   Q6PJ45; Q9NV40;
DE   RecName: Full=Echinoderm microtubule-associated protein-like 4;
DE            Short=EMAP-4;
DE   AltName: Full=Restrictedly overexpressed proliferation-associated protein;
DE   AltName: Full=Ropp 120;
GN   Name=EML4; Synonyms=C2orf2, EMAPL4;
DR   GO; GO:0007017; P:microtubule-based process; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Ensembl.
//
ID   EMAL5_HUMAN             Reviewed;        1969 AA.
AC   Q05BV3; B9EK59; Q5H9N6; Q6UYC9; Q6ZRP3; Q6ZT03;
DE   RecName: Full=Echinoderm microtubule-associated protein-like 5;
DE            Short=EMAP-5;
GN   Name=EML5;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   EMAL6_HUMAN             Reviewed;        1958 AA.
AC   Q6ZMW3; A8MUB5; B6ZDG7;
DE   RecName: Full=Echinoderm microtubule-associated protein-like 6;
DE            Short=EMAP-6;
DE   AltName: Full=Echinoderm microtubule-associated protein-like 5-like;
GN   Name=EML6; Synonyms=EML5L;
//
ID   EMARD_HUMAN             Reviewed;         678 AA.
AC   Q5T6L9; B4DFH0; F8WAF1; Q3ZCS8; Q5T6L8; Q9NUT5; Q9NVU2;
DE   RecName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein;
DE            Short=ER membrane-associated RNA degradation protein;
GN   Name=ERMARD; Synonyms=C6orf70;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   EMC2_HUMAN              Reviewed;         297 AA.
AC   Q15006; Q8WUE1;
DE   RecName: Full=ER membrane protein complex subunit 2;
DE   AltName: Full=Tetratricopeptide repeat protein 35;
DE            Short=TPR repeat protein 35;
GN   Name=EMC2; Synonyms=KIAA0103, TTC35;
//
ID   EMC10_HUMAN             Reviewed;         262 AA.
AC   Q5UCC4; Q5UCC6; Q69YT5; Q6UWP3; Q86YL4; Q8N541;
DE   RecName: Full=ER membrane protein complex subunit 10;
DE   AltName: Full=Hematopoietic signal peptide-containing membrane domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=EMC10; Synonyms=C19orf63, HSM1, INM02; ORFNames=UNQ764/PRO1556;
//
ID   EMC1_HUMAN              Reviewed;         993 AA.
AC   Q8N766; A8K6F3; Q14700; Q5TG62; Q63HL0; Q63HL3; Q8NBH8;
DE   RecName: Full=ER membrane protein complex subunit 1;
DE   Flags: Precursor;
GN   Name=EMC1; Synonyms=KIAA0090; ORFNames=PSEC0263;
//
ID   EMB_HUMAN               Reviewed;         327 AA.
AC   Q6PCB8; B7Z6S3;
DE   RecName: Full=Embigin;
DE   Flags: Precursor;
GN   Name=EMB;
DR   GO; GO:0097159; F:organic cyclic compound binding; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0035879; P:plasma membrane lactate transport; ISS:UniProtKB.
//
ID   EMC3_HUMAN              Reviewed;         261 AA.
AC   Q9P0I2; B2R4Z9; Q53GH8; Q6ZMC2;
DE   RecName: Full=ER membrane protein complex subunit 3;
DE   AltName: Full=Transmembrane protein 111;
GN   Name=EMC3; Synonyms=TMEM111;
//
ID   EMC4_HUMAN              Reviewed;         183 AA.
AC   Q5J8M3; A8K3A9; B4DJQ4; Q96KX9; Q9BUI5; Q9P0T9;
DE   RecName: Full=ER membrane protein complex subunit 4;
DE   AltName: Full=Cell proliferation-inducing gene 17 protein;
DE   AltName: Full=Transmembrane protein 85;
GN   Name=EMC4; Synonyms=TMEM85; ORFNames=HSPC184, PIG17;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   EMC6_HUMAN              Reviewed;         110 AA.
AC   Q9BV81;
DE   RecName: Full=ER membrane protein complex subunit 6;
DE   AltName: Full=Transmembrane protein 93;
GN   Name=EMC6; Synonyms=TMEM93;
//
ID   EMC7_HUMAN              Reviewed;         242 AA.
AC   Q9NPA0; B2RC00; Q96ED5;
DE   RecName: Full=ER membrane protein complex subunit 7;
DE   Flags: Precursor;
GN   Name=EMC7; Synonyms=C11orf3, C15orf24; ORFNames=HT022, UNQ905/PRO1926;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0017076; F:purine nucleotide binding; NAS:UniProtKB.
//
ID   EMC8_HUMAN              Reviewed;         210 AA.
AC   O43402; C9JB21;
DE   RecName: Full=ER membrane protein complex subunit 8;
DE   AltName: Full=Neighbor of COX4;
DE   AltName: Full=Protein FAM158B;
GN   Name=EMC8; Synonyms=C16orf2, C16orf4, COX4AL, COX4NB, FAM158B, NOC4;
//
ID   EMC9_HUMAN              Reviewed;         208 AA.
AC   Q9Y3B6; D3DS60; Q9BUM3;
DE   RecName: Full=ER membrane protein complex subunit 9;
DE   AltName: Full=Protein FAM158A;
GN   Name=EMC9; Synonyms=C14orf122, FAM158A; ORFNames=CGI-112;
//
ID   EMD_HUMAN               Reviewed;         254 AA.
AC   P50402; Q6FI02;
DE   RecName: Full=Emerin;
GN   Name=EMD; Synonyms=EDMD, STA;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IMP:BHF-UCL.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   EME1_HUMAN              Reviewed;         570 AA.
AC   Q96AY2; Q96N62;
DE   RecName: Full=Crossover junction endonuclease EME1;
DE            EC=3.1.22.-;
DE   AltName: Full=MMS4 homolog;
DE            Short=hMMS4;
GN   Name=EME1; Synonyms=MMS4;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
//
ID   EME2_HUMAN              Reviewed;         379 AA.
AC   A4GXA9; Q8TEP2; Q96RY3;
DE   RecName: Full=Probable crossover junction endonuclease EME2;
DE            EC=3.1.22.-;
GN   Name=EME2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
//
ID   EMID1_HUMAN             Reviewed;         441 AA.
AC   Q96A84; B0QYK6; Q6ICG1; Q86SS7;
DE   RecName: Full=EMI domain-containing protein 1;
DE   AltName: Full=Emilin and multimerin domain-containing protein 1;
DE            Short=Emu1;
DE   Flags: Precursor;
GN   Name=EMID1; Synonyms=EMU1;
//
ID   EMIL1_HUMAN             Reviewed;        1016 AA.
AC   Q9Y6C2; A5PL03; Q53SY9; Q96G58; Q9UG76;
DE   RecName: Full=EMILIN-1;
DE   AltName: Full=Elastin microfibril interface-located protein 1;
DE            Short=Elastin microfibril interfacer 1;
DE   Flags: Precursor;
GN   Name=EMILIN1; Synonyms=EMI;
DR   GO; GO:0030023; F:extracellular matrix constituent conferring elasticity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   EMIL2_HUMAN             Reviewed;        1053 AA.
AC   Q9BXX0; B2RMY3; Q8NBH3; Q96JQ4;
DE   RecName: Full=EMILIN-2;
DE   AltName: Full=Elastin microfibril interface-located protein 2;
DE            Short=Elastin microfibril interfacer 2;
DE   AltName: Full=Protein FOAP-10;
DE   Flags: Precursor;
GN   Name=EMILIN2;
DR   GO; GO:0030023; F:extracellular matrix constituent conferring elasticity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   EMIL3_HUMAN             Reviewed;         766 AA.
AC   Q9NT22; Q495S6; Q495S7; Q76KT4;
DE   RecName: Full=EMILIN-3;
DE   AltName: Full=EMILIN-5;
DE   AltName: Full=Elastin microfibril interface-located protein 3;
DE            Short=Elastin microfibril interfacer 3;
DE   AltName: Full=Elastin microfibril interface-located protein 5;
DE            Short=Elastin microfibril interfacer 5;
DE   Flags: Precursor;
GN   Name=EMILIN3; Synonyms=C20orf130, EMILIN5;
//
ID   EMP1_HUMAN              Reviewed;         157 AA.
AC   P54849; B2R5N1; O00681; Q13481; Q13834;
DE   RecName: Full=Epithelial membrane protein 1;
DE            Short=EMP-1;
DE   AltName: Full=CL-20;
DE   AltName: Full=Protein B4B;
DE   AltName: Full=Tumor-associated membrane protein;
GN   Name=EMP1; Synonyms=B4B, TMP;
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   EMP2_HUMAN              Reviewed;         167 AA.
AC   P54851; B2R7V6; D3DUF8;
DE   RecName: Full=Epithelial membrane protein 2;
DE            Short=EMP-2;
DE   AltName: Full=Protein XMP;
GN   Name=EMP2; Synonyms=XMP;
DR   GO; GO:0005178; F:integrin binding; IPI:MGI.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:MGI.
DR   GO; GO:2001046; P:positive regulation of integrin-mediated signaling pathway; IDA:MGI.
//
ID   EMP3_HUMAN              Reviewed;         163 AA.
AC   P54852; Q6FH01;
DE   RecName: Full=Epithelial membrane protein 3;
DE            Short=EMP-3;
DE   AltName: Full=Hematopoietic neural membrane protein 1;
DE            Short=HNMP-1;
DE   AltName: Full=Protein YMP;
GN   Name=EMP3; Synonyms=YMP;
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   EMR1_HUMAN              Reviewed;         886 AA.
AC   Q14246; A6NHV2; B7Z486; B7Z489; E7EPX9; E9PD45; H9KV79; Q2I7G5;
AC   Q6ZMN0; Q8NGA7;
DE   RecName: Full=EGF-like module-containing mucin-like hormone receptor-like 1;
DE   AltName: Full=EGF-like module receptor 1;
DE   AltName: Full=EMR1 hormone receptor;
DE   Flags: Precursor;
GN   Name=EMR1; Synonyms=TM7LN3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   EMR2_HUMAN              Reviewed;         823 AA.
AC   Q9UHX3; B4DQ96; E7ESD7; E9PBR1; E9PEL6; E9PFQ5; E9PG91; Q8NG96;
AC   Q9Y4B1;
DE   RecName: Full=EGF-like module-containing mucin-like hormone receptor-like 2;
DE   AltName: Full=EGF-like module receptor 2;
DE   AltName: CD_antigen=CD312;
DE   Flags: Precursor;
GN   Name=EMR2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0035374; F:chondroitin sulfate binding; IMP:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007155; P:cell adhesion; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0071621; P:granulocyte chemotaxis; IMP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   EMR4_HUMAN              Reviewed;         457 AA.
AC   Q86SQ3; Q86SP1;
DE   RecName: Full=Putative EGF-like module-containing mucin-like hormone receptor-like 4;
DE   AltName: Full=EGF-like module receptor 4;
DE   AltName: Full=G-protein coupled receptor 127;
DE   AltName: Full=G-protein coupled receptor PGR16;
DE   Flags: Precursor;
GN   Name=EMR4P; Synonyms=EMR4, GPR127, PGR16;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   EMR3_HUMAN              Reviewed;         652 AA.
AC   Q9BY15;
DE   RecName: Full=EGF-like module-containing mucin-like hormone receptor-like 3;
DE   AltName: Full=EGF-like module receptor 3;
DE   Contains:
DE     RecName: Full=EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha;
DE   Contains:
DE     RecName: Full=EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta;
DE   Flags: Precursor;
GN   Name=EMR3; ORFNames=UNQ683/PRO1562;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   EMRE_HUMAN              Reviewed;         107 AA.
AC   Q9H4I9; B2R5D1; Q8TAB9;
DE   RecName: Full=Essential MCU regulator, mitochondrial;
DE   AltName: Full=Single-pass membrane protein with aspartate-rich tail 1, mitochondrial;
DE   Flags: Precursor;
GN   Name=SMDT1; Synonyms=C22orf32, EMRE;
DR   GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IMP:UniProtKB.
//
ID   EMSA1_HUMAN             Reviewed;        1045 AA.
AC   Q6PJG2; Q6PK13; Q6PK59; Q6ZS23;
DE   RecName: Full=ELM2 and SANT domain-containing protein 1;
GN   Name=ELMSAN1; Synonyms=C14orf117, C14orf43;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EMSY_HUMAN              Reviewed;        1322 AA.
AC   Q7Z589; B7ZKT8; B7ZKU0; B7ZKU2; Q17RM7; Q4G109; Q8NBU6; Q8TE50;
AC   Q9H8I9; Q9NRH0;
DE   RecName: Full=Protein EMSY;
GN   Name=EMSY; Synonyms=C11orf30; ORFNames=GL002;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EMX1_HUMAN              Reviewed;         257 AA.
AC   Q04741; Q0D2P0; Q53T30; Q86XB0;
DE   RecName: Full=Homeobox protein EMX1;
DE   AltName: Full=Empty spiracles homolog 1;
DE   AltName: Full=Empty spiracles-like protein 1;
GN   Name=EMX1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048854; P:brain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   EMX2_HUMAN              Reviewed;         252 AA.
AC   Q04743; G3V305; Q96NN8; Q9BQF4;
DE   RecName: Full=Homeobox protein EMX2;
DE   AltName: Full=Empty spiracles homolog 2;
DE   AltName: Full=Empty spiracles-like protein 2;
GN   Name=EMX2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0021885; P:forebrain cell migration; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0072001; P:renal system development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   ENAH_HUMAN              Reviewed;         591 AA.
AC   Q8N8S7; D0PQI2; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q9NVF3; Q9UFB8;
DE   RecName: Full=Protein enabled homolog;
GN   Name=ENAH; Synonyms=MENA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   ENAM_HUMAN              Reviewed;        1142 AA.
AC   Q9NRM1; Q17RI5; Q9H3D1;
DE   RecName: Full=Enamelin;
DE   Flags: Precursor;
GN   Name=ENAM;
DR   GO; GO:0097186; P:amelogenesis; IEA:Ensembl.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
//
ID   ENASE_HUMAN             Reviewed;         743 AA.
AC   Q8NFI3; Q659F0; Q8TB86; Q9H6U4;
DE   RecName: Full=Cytosolic endo-beta-N-acetylglucosaminidase;
DE            Short=ENGase;
DE            EC=3.2.1.96;
GN   Name=ENGASE;
DR   GO; GO:0033925; F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity; IEA:UniProtKB-EC.
//
ID   ENC1_HUMAN              Reviewed;         589 AA.
AC   O14682; B4DHJ1; E9PFU0; O75464; Q9UPG9;
DE   RecName: Full=Ectoderm-neural cortex protein 1;
DE            Short=ENC-1;
DE   AltName: Full=Kelch-like protein 37;
DE   AltName: Full=Nuclear matrix protein NRP/B;
DE   AltName: Full=p53-induced gene 10 protein;
GN   Name=ENC1; Synonyms=KLHL37, NRPB, PIG10;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   ENDD1_HUMAN             Reviewed;         500 AA.
AC   O94919; A8K6K8; Q6GQY5; Q8TAQ8;
DE   RecName: Full=Endonuclease domain-containing 1 protein;
DE            EC=3.1.30.-;
DE   Flags: Precursor;
GN   Name=ENDOD1; Synonyms=KIAA0830;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ENDOU_HUMAN             Reviewed;         410 AA.
AC   P21128; B2RBJ3; B3KQS7; B7Z6E1; Q2NKJ4;
DE   RecName: Full=Poly(U)-specific endoribonuclease;
DE            EC=3.1.-.-;
DE   AltName: Full=Placental protein 11;
DE            Short=PP11;
DE   AltName: Full=Protein endoU;
DE   AltName: Full=Uridylate-specific endoribonuclease;
DE   Flags: Precursor;
GN   Name=ENDOU;
DR   GO; GO:0004521; F:endoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; TAS:UniProtKB.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
//
ID   ENDOV_HUMAN             Reviewed;         282 AA.
AC   Q8N8Q3; I3L3S4; Q6P2G2; Q86X99; Q8NAK0;
DE   RecName: Full=Endonuclease V;
DE            Short=hEndoV;
DE            EC=3.1.26.-;
DE   AltName: Full=Inosine-specific endoribonuclease;
GN   Name=ENDOV;
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; ISS:UniProtKB.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0043566; F:structure-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; ISS:GOC.
DR   GO; GO:0006281; P:DNA repair; ISS:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
//
ID   ENH3_HUMAN              Reviewed;         555 AA.
AC   Q9N2J8;
DE   RecName: Full=HERV-H_2q24.1 provirus ancestral Env polyprotein;
DE   AltName: Full=Env protein HERV-H/p59;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-H/env59;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
//
ID   ENHO_HUMAN              Reviewed;          76 AA.
AC   Q6UWT2; Q8N666;
DE   RecName: Full=Adropin;
DE   AltName: Full=Energy homeostasis-associated protein;
DE   Flags: Precursor;
GN   Name=ENHO; Synonyms=C9orf165; ORFNames=UNQ470/PRO830;
//
ID   ENH1_HUMAN              Reviewed;         584 AA.
AC   Q9N2K0; O00354; Q96L63; Q9UNM3;
DE   RecName: Full=HERV-H_2q24.3 provirus ancestral Env polyprotein;
DE   AltName: Full=Env protein HERV-H/p62;
DE   AltName: Full=Env protein HERV-H19;
DE   AltName: Full=Env protein HERV-Hcl.3;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-H/env62;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
//
ID   ENK11_HUMAN             Reviewed;         588 AA.
AC   P61566;
DE   RecName: Full=HERV-K_22q11.21 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K101 envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK12_HUMAN             Reviewed;         588 AA.
AC   P61567;
DE   RecName: Full=HERV-K_1q22 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K(III) envelope protein;
DE   AltName: Full=HERV-K102 envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK13_HUMAN             Reviewed;         191 AA.
AC   P61568;
DE   RecName: Full=HERV-K_1p13.3 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   Includes:
DE     RecName: Full=Truncated surface protein;
DE              Short=SU;
//
ID   ENK14_HUMAN             Reviewed;         482 AA.
AC   Q9NX77; A8K9G3;
DE   RecName: Full=HERV-K_16p3.3 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK17_HUMAN             Reviewed;         661 AA.
AC   P61570;
DE   RecName: Full=HERV-K_11q22.1 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK1_HUMAN              Reviewed;         698 AA.
AC   P61565;
DE   RecName: Full=HERV-K_12q14.1 provirus ancestral Env polyprotein;
DE   AltName: Full=EnvK1 protein;
DE   AltName: Full=Envelope polyprotein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK2_HUMAN              Reviewed;         699 AA.
AC   Q69384; Q8TD93; Q9UBU4; Q9YNA5; Q9YNA9;
DE   RecName: Full=HERV-K_7p22.1 provirus ancestral Env polyprotein;
DE   AltName: Full=EnvK2 protein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K(C7) envelope protein;
DE   AltName: Full=HERV-K(HML-2.HOM) envelope protein;
DE   AltName: Full=HERV-K108 envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
GN   Name=ERVK6;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK3_HUMAN              Reviewed;         699 AA.
AC   O71037; Q69386; Q9YNA7;
DE   RecName: Full=HERV-K_19q12 provirus ancestral Env polyprotein;
DE   AltName: Full=EnvK3 protein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K(C19) envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK4_HUMAN              Reviewed;         698 AA.
AC   Q9UKH3;
DE   RecName: Full=HERV-K_6q14.1 provirus ancestral Env polyprotein;
DE   AltName: Full=EnvK4 protein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K(C6) envelope protein;
DE   AltName: Full=HERV-K109 envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK5_HUMAN              Reviewed;         699 AA.
AC   Q902F9;
DE   RecName: Full=HERV-K_19p13.11 provirus ancestral Env polyprotein;
DE   AltName: Full=EnvK5 protein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K113 envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK6_HUMAN              Reviewed;         699 AA.
AC   Q902F8;
DE   RecName: Full=HERV-K_8p23.1 provirus ancestral Env polyprotein;
DE   AltName: Full=EnvK6 protein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K115 envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK7_HUMAN              Reviewed;         560 AA.
AC   O42043; O95280; Q96PI3; Q96PI6; Q9QC06;
DE   RecName: Full=HERV-K_1q23.3 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K(C1a) envelope protein;
DE   AltName: Full=HERV-K110 envelope protein;
DE   AltName: Full=HERV-K18 envelope protein;
DE   AltName: Full=HERV-K18 superantigen;
DE   AltName: Full=IDDMK1,2 22 envelope protein;
DE   AltName: Full=IDDMK1,2 22 superantigen;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   ENK8_HUMAN              Reviewed;         245 AA.
AC   Q9HDB8;
DE   RecName: Full=HERV-K_3q12.3 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-K(II) envelope protein;
DE   Includes:
DE     RecName: Full=Truncated surface protein;
DE              Short=SU;
GN   Name=ERVK-5; Synonyms=ERVK5;
//
ID   ENKD1_HUMAN             Reviewed;         346 AA.
AC   Q9H0I2; Q6UWD7;
DE   RecName: Full=Enkurin domain-containing protein 1;
GN   Name=ENKD1; Synonyms=C16orf48; ORFNames=UNQ6410/PRO21183;
//
ID   ENKUR_HUMAN             Reviewed;         256 AA.
AC   Q8TC29; A8K8Y0; D3DRV2;
DE   RecName: Full=Enkurin;
GN   Name=ENKUR; Synonyms=C10orf63;
//
ID   ENL_HUMAN               Reviewed;         559 AA.
AC   Q03111; Q14768;
DE   RecName: Full=Protein ENL;
DE   AltName: Full=YEATS domain-containing protein 1;
GN   Name=MLLT1; Synonyms=ENL, LTG19, YEATS1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ENO4_HUMAN              Reviewed;         628 AA.
AC   A6NNW6; B8ZZN9;
DE   RecName: Full=Enolase-like protein ENO4;
GN   Name=ENO4; Synonyms=C10orf134;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:InterPro.
//
ID   ENOA_HUMAN              Reviewed;         434 AA.
AC   P06733; B2RD59; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5;
AC   Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55;
DE   RecName: Full=Alpha-enolase;
DE            EC=4.2.1.11;
DE   AltName: Full=2-phospho-D-glycerate hydro-lyase;
DE   AltName: Full=C-myc promoter-binding protein;
DE   AltName: Full=Enolase 1;
DE   AltName: Full=MBP-1;
DE   AltName: Full=MPB-1;
DE   AltName: Full=Non-neural enolase;
DE            Short=NNE;
DE   AltName: Full=Phosphopyruvate hydratase;
DE   AltName: Full=Plasminogen-binding protein;
GN   Name=ENO1; Synonyms=ENO1L1, MBPB1, MPB1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004634; F:phosphopyruvate hydratase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ENOB_HUMAN              Reviewed;         434 AA.
AC   P13929; B4DUI6; B4DUM6; D3DTL2; E7ENK8; Q96AE2;
DE   RecName: Full=Beta-enolase;
DE            EC=4.2.1.11;
DE   AltName: Full=2-phospho-D-glycerate hydro-lyase;
DE   AltName: Full=Enolase 3;
DE   AltName: Full=Muscle-specific enolase;
DE            Short=MSE;
DE   AltName: Full=Skeletal muscle enolase;
GN   Name=ENO3;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004634; F:phosphopyruvate hydratase activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ENOF1_HUMAN             Reviewed;         443 AA.
AC   Q7L5Y1; A6NMP3; A8K9R5; D3DUH0; Q15407; Q15594; Q15595; Q9HAS5;
AC   Q9HAS6;
DE   RecName: Full=Mitochondrial enolase superfamily member 1;
DE            EC=5.-.-.-;
DE   AltName: Full=Antisense RNA to thymidylate synthase;
DE            Short=rTS;
GN   Name=ENOSF1; Synonyms=RTS, TYMSAS;
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009063; P:cellular amino acid catabolic process; IEA:InterPro.
//
ID   ENOG_HUMAN              Reviewed;         434 AA.
AC   P09104; Q96J33;
DE   RecName: Full=Gamma-enolase;
DE            EC=4.2.1.11;
DE   AltName: Full=2-phospho-D-glycerate hydro-lyase;
DE   AltName: Full=Enolase 2;
DE   AltName: Full=Neural enolase;
DE   AltName: Full=Neuron-specific enolase;
DE            Short=NSE;
GN   Name=ENO2;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004634; F:phosphopyruvate hydratase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ENOPH_HUMAN             Reviewed;         261 AA.
AC   Q9UHY7; Q7Z4C5; Q9BVC2;
DE   RecName: Full=Enolase-phosphatase E1;
DE            EC=3.1.3.77;
DE   AltName: Full=2,3-diketo-5-methylthio-1-phosphopentane phosphatase;
DE   AltName: Full=MASA homolog;
GN   Name=ENOPH1; Synonyms=MASA; ORFNames=MSTP145;
DR   GO; GO:0043874; F:acireductone synthase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; IDA:UniProtKB.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   ENOX1_HUMAN             Reviewed;         643 AA.
AC   Q8TC92; A4GU15; A6NMH9; Q2TU81; Q5VT11; Q9NWE0;
DE   RecName: Full=Ecto-NOX disulfide-thiol exchanger 1;
DE   AltName: Full=Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase;
DE            Short=cCNOX;
DE   AltName: Full=Cell proliferation-inducing gene 38 protein;
DE   AltName: Full=Constitutive Ecto-NOX;
DE            Short=cNOX;
DE   Includes:
DE     RecName: Full=Hydroquinone [NADH] oxidase;
DE              EC=1.-.-.-;
DE   Includes:
DE     RecName: Full=Protein disulfide-thiol oxidoreductase;
DE              EC=1.-.-.-;
GN   Name=ENOX1; ORFNames=PIG38;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
//
ID   ENOX2_HUMAN             Reviewed;         610 AA.
AC   Q16206; A8K197; A8K1C2; Q5VTJ1; Q5VTJ2; Q8WUX0; Q9NTP6; Q9UH82;
DE   RecName: Full=Ecto-NOX disulfide-thiol exchanger 2;
DE   AltName: Full=APK1 antigen;
DE   AltName: Full=Cytosolic ovarian carcinoma antigen 1;
DE   AltName: Full=Tumor-associated hydroquinone oxidase;
DE            Short=tNOX;
DE   Includes:
DE     RecName: Full=Hydroquinone [NADH] oxidase;
DE              EC=1.-.-.-;
DE   Includes:
DE     RecName: Full=Protein disulfide-thiol oxidoreductase;
DE              EC=1.-.-.-;
GN   Name=ENOX2; Synonyms=COVA1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0007624; P:ultradian rhythm; IDA:UniProtKB.
//
ID   ENPLL_HUMAN             Reviewed;         399 AA.
AC   Q58FF3;
DE   RecName: Full=Putative endoplasmin-like protein;
DE   AltName: Full=Putative heat shock protein 90 kDa beta member 2;
GN   Name=HSP90B2P; Synonyms=GRP94B, GRP94P1, TRAP1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   ENPL_HUMAN              Reviewed;         803 AA.
AC   P14625; Q96A97;
DE   RecName: Full=Endoplasmin;
DE   AltName: Full=94 kDa glucose-regulated protein;
DE            Short=GRP-94;
DE   AltName: Full=Heat shock protein 90 kDa beta member 1;
DE   AltName: Full=Tumor rejection antigen 1;
DE   AltName: Full=gp96 homolog;
DE   Flags: Precursor;
GN   Name=HSP90B1; Synonyms=GRP94, TRA1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IDA:MGI.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0046790; F:virion binding; IPI:UniProtKB.
DR   GO; GO:0031247; P:actin rod assembly; IDA:MGI.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071318; P:cellular response to ATP; IDA:MGI.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; NAS:UniProtKB.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IDA:MGI.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0051208; P:sequestering of calcium ion; NAS:UniProtKB.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   ENPP1_HUMAN             Reviewed;         925 AA.
AC   P22413; Q5T9R6; Q9NPZ3; Q9P1P6; Q9UP61; Q9Y6K3;
DE   RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 1;
DE            Short=E-NPP 1;
DE   AltName: Full=Membrane component chromosome 6 surface marker 1;
DE   AltName: Full=Phosphodiesterase I/nucleotide pyrophosphatase 1;
DE   AltName: Full=Plasma-cell membrane glycoprotein PC-1;
DE   Includes:
DE     RecName: Full=Alkaline phosphodiesterase I;
DE              EC=3.1.4.1;
DE   Includes:
DE     RecName: Full=Nucleotide pyrophosphatase;
DE              Short=NPPase;
DE              EC=3.6.1.9;
GN   Name=ENPP1; Synonyms=M6S1, NPPS, PC1, PDNP1;
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; IC:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.
DR   GO; GO:0035529; F:NADH pyrophosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0004551; F:nucleotide diphosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0004528; F:phosphodiesterase I activity; ISS:UniProtKB.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:UniProtKB.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0030505; P:inorganic diphosphate transport; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0046325; P:negative regulation of glucose import; IDA:BHF-UCL.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; ISS:GOC.
DR   GO; GO:0009143; P:nucleoside triphosphate catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030500; P:regulation of bone mineralization; IC:BHF-UCL.
DR   GO; GO:0006771; P:riboflavin metabolic process; TAS:Reactome.
DR   GO; GO:0030730; P:sequestering of triglyceride; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   ENPP2_HUMAN             Reviewed;         863 AA.
AC   Q13822; A8UHA1; E9PHP7; Q13827; Q14555; Q15117; Q9UCQ8; Q9UCR0;
AC   Q9UCR1; Q9UCR2; Q9UCR3; Q9UCR4;
DE   RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 2;
DE            Short=E-NPP 2;
DE            EC=3.1.4.39;
DE   AltName: Full=Autotaxin;
DE   AltName: Full=Extracellular lysophospholipase D;
DE            Short=LysoPLD;
DE   Flags: Precursor;
GN   Name=ENPP2; Synonyms=ATX, PDNP2;
DR   GO; GO:0047391; F:alkylglycerophosphoethanolamine phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0016787; F:hydrolase activity; TAS:UniProtKB.
DR   GO; GO:0004622; F:lysophospholipase activity; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004551; F:nucleotide diphosphatase activity; TAS:ProtInc.
DR   GO; GO:0004528; F:phosphodiesterase I activity; TAS:ProtInc.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0034638; P:phosphatidylcholine catabolic process; IDA:UniProtKB.
DR   GO; GO:0009395; P:phospholipid catabolic process; IDA:UniProt.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:UniProtKB.
//
ID   ENPP3_HUMAN             Reviewed;         875 AA.
AC   O14638; Q5JTL3;
DE   RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 3;
DE            Short=E-NPP 3;
DE   AltName: Full=Phosphodiesterase I beta;
DE            Short=PD-Ibeta;
DE   AltName: Full=Phosphodiesterase I/nucleotide pyrophosphatase 3;
DE   AltName: CD_antigen=CD203c;
DE   Includes:
DE     RecName: Full=Alkaline phosphodiesterase I;
DE              EC=3.1.4.1;
DE   Includes:
DE     RecName: Full=Nucleotide pyrophosphatase;
DE              Short=NPPase;
DE              EC=3.6.1.9;
GN   Name=ENPP3; Synonyms=PDNP3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035529; F:NADH pyrophosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0004551; F:nucleotide diphosphatase activity; TAS:ProtInc.
DR   GO; GO:0004528; F:phosphodiesterase I activity; TAS:ProtInc.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0009143; P:nucleoside triphosphate catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; IDA:BHF-UCL.
//
ID   ENPP4_HUMAN             Reviewed;         453 AA.
AC   Q9Y6X5; A8K5G1; Q7L2N1;
DE   RecName: Full=Bis(5'-adenosyl)-triphosphatase ENPP4;
DE            EC=3.6.1.29;
DE   AltName: Full=AP3A hydrolase;
DE            Short=AP3Aase;
DE   AltName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 4;
DE            Short=E-NPP 4;
DE            Short=NPP-4;
DE   Flags: Precursor;
GN   Name=ENPP4; Synonyms=KIAA0879, NPP4;
DR   GO; GO:0047710; F:bis(5'-adenosyl)-triphosphatase activity; IDA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IDA:UniProt.
DR   GO; GO:0046130; P:purine ribonucleoside catabolic process; IDA:UniProt.
//
ID   ENPP5_HUMAN             Reviewed;         477 AA.
AC   Q9UJA9; Q5TFV2; Q6UX49;
DE   RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 5;
DE            Short=E-NPP 5;
DE            Short=NPP-5;
DE            EC=3.1.-.-;
DE   Flags: Precursor;
GN   Name=ENPP5; ORFNames=UNQ550/PRO1107;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007154; P:cell communication; IEA:Ensembl.
//
ID   ENPP6_HUMAN             Reviewed;         440 AA.
AC   Q6UWR7; Q4W5Q1; Q96M57;
DE   RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 6;
DE            Short=E-NPP 6;
DE            Short=NPP-6;
DE            EC=3.1.4.-;
DE            EC=3.1.4.38;
DE   AltName: Full=Choline-specific glycerophosphodiester phosphodiesterase;
DE   AltName: Full=Glycerophosphocholine cholinephosphodiesterase;
DE            Short=GPC-Cpde;
DE   Flags: Precursor;
GN   Name=ENPP6; ORFNames=UNQ1889/PRO4334;
DR   GO; GO:0047390; F:glycerophosphocholine cholinephosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0019695; P:choline metabolic process; IDA:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IDA:UniProtKB.
//
ID   ENPP7_HUMAN             Reviewed;         458 AA.
AC   Q6UWV6; Q6ZTS5; Q8IUS8;
DE   RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7;
DE            Short=E-NPP 7;
DE            Short=NPP-7;
DE            EC=3.1.4.12;
DE   AltName: Full=Alkaline sphingomyelin phosphodiesterase;
DE   AltName: Full=Intestinal alkaline sphingomyelinase;
DE            Short=Alk-SMase;
DE   Flags: Precursor;
GN   Name=ENPP7; ORFNames=UNQ3077/PRO9912;
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006684; P:sphingomyelin metabolic process; IDA:UniProtKB.
//
ID   ENR1_HUMAN              Reviewed;         604 AA.
AC   Q14264;
DE   RecName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein;
DE   AltName: Full=ERV-3 envelope protein;
DE            Short=ERV3 envelope protein;
DE   AltName: Full=ERV3-1 envelope protein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-R envelope protein;
DE            Short=ERV-R envelope protein;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
GN   Name=ERV3-1; Synonyms=ERV3;
//
ID   ENSA_HUMAN              Reviewed;         121 AA.
AC   O43768; A8K1Z9; E9PB69; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2;
AC   Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0;
DE   RecName: Full=Alpha-endosulfine;
DE   AltName: Full=ARPP-19e;
GN   Name=ENSA;
DR   GO; GO:0008200; F:ion channel inhibitor activity; TAS:ProtInc.
DR   GO; GO:0019212; F:phosphatase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0050790; P:regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ENT1_HUMAN              Reviewed;         626 AA.
AC   P61550; I7GPQ9;
DE   RecName: Full=HERV-T_19q13.11 provirus ancestral Env polyprotein;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-T Env protein;
DE   Includes:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE   Includes:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE   Flags: Precursor;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019058; P:viral life cycle; IEA:InterPro.
//
ID   ENTD1_HUMAN             Reviewed;         607 AA.
AC   Q8IYW4; B0QYD5; Q5H9F7; Q96LK3;
DE   RecName: Full=ENTH domain-containing protein 1;
DE   AltName: Full=Epsin-2B;
GN   Name=ENTHD1;
//
ID   ENTK_HUMAN              Reviewed;        1019 AA.
AC   P98073; Q2NKL7;
DE   RecName: Full=Enteropeptidase;
DE            EC=3.4.21.9;
DE   AltName: Full=Enterokinase;
DE   AltName: Full=Serine protease 7;
DE   AltName: Full=Transmembrane protease serine 15;
DE   Contains:
DE     RecName: Full=Enteropeptidase non-catalytic heavy chain;
DE   Contains:
DE     RecName: Full=Enteropeptidase catalytic light chain;
DE   Flags: Precursor;
GN   Name=TMPRSS15; Synonyms=ENTK, PRSS7;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   ENTP1_HUMAN             Reviewed;         510 AA.
AC   P49961; A9Z1X8; B4DWB9; B4E1X1; B7Z599; G3XAF6; Q5T561; Q5T562;
AC   Q86VV3; Q9UQQ9; Q9Y3Q9;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 1;
DE            Short=NTPDase 1;
DE            EC=3.6.1.5;
DE   AltName: Full=Ecto-ATP diphosphohydrolase 1;
DE            Short=Ecto-ATPDase 1;
DE            Short=Ecto-ATPase 1;
DE   AltName: Full=Ecto-apyrase;
DE   AltName: Full=Lymphoid cell activation antigen;
DE   AltName: CD_antigen=CD39;
GN   Name=ENTPD1; Synonyms=CD39;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside-diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006200; P:ATP catabolic process; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0009181; P:purine ribonucleoside diphosphate catabolic process; IEA:Ensembl.
//
ID   ENTP2_HUMAN             Reviewed;         495 AA.
AC   Q9Y5L3; O15464; Q5SPY6; Q5SPY7;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 2;
DE            Short=NTPDase 2;
DE            EC=3.6.1.-;
DE   AltName: Full=CD39 antigen-like 1;
DE   AltName: Full=Ecto-ATP diphosphohydrolase 2;
DE            Short=Ecto-ATPDase 2;
DE            Short=Ecto-ATPase 2;
GN   Name=ENTPD2; Synonyms=CD39L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside-diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0009181; P:purine ribonucleoside diphosphate catabolic process; IEA:Ensembl.
//
ID   ENTP3_HUMAN             Reviewed;         529 AA.
AC   O75355; B2R8D0; G5E9N0; O60495; Q8N6K2;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 3;
DE            Short=NTPDase 3;
DE            EC=3.6.1.5;
DE   AltName: Full=CD39 antigen-like 3;
DE   AltName: Full=Ecto-ATP diphosphohydrolase 3;
DE            Short=Ecto-ATPDase 3;
DE            Short=Ecto-ATPase 3;
DE   AltName: Full=Ecto-apyrase 3;
DE   AltName: Full=HB6;
GN   Name=ENTPD3; Synonyms=CD39L3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside-diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:Ensembl.
DR   GO; GO:0009134; P:nucleoside diphosphate catabolic process; IEA:Ensembl.
DR   GO; GO:0009143; P:nucleoside triphosphate catabolic process; IEA:Ensembl.
//
ID   ENTP4_HUMAN             Reviewed;         616 AA.
AC   Q9Y227; D3DSS3; O15092;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 4;
DE            Short=NTPDase 4;
DE            EC=3.6.1.6;
DE   AltName: Full=Lysosomal apyrase-like protein of 70 kDa;
DE   AltName: Full=Uridine-diphosphatase;
DE            Short=UDPase;
GN   Name=ENTPD4; Synonyms=KIAA0392, LALP70, LYSAL1;
DR   GO; GO:0045134; F:uridine-diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006256; P:UDP catabolic process; IDA:UniProtKB.
//
ID   ENTP5_HUMAN             Reviewed;         428 AA.
AC   O75356; A1L4C5; Q96RX0;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 5;
DE            Short=NTPDase 5;
DE            EC=3.6.1.6;
DE   AltName: Full=CD39 antigen-like 4;
DE   AltName: Full=ER-UDPase;
DE   AltName: Full=Guanosine-diphosphatase ENTPD5;
DE            Short=GDPase ENTPD5;
DE            EC=3.6.1.42;
DE   AltName: Full=Nucleoside diphosphatase;
DE   AltName: Full=Uridine-diphosphatase ENTPD5;
DE            Short=UDPase ENTPD5;
DE   Flags: Precursor;
GN   Name=ENTPD5; Synonyms=CD39L4, PCPH;
DR   GO; GO:0004382; F:guanosine-diphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0045134; F:uridine-diphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; ISS:UniProtKB.
DR   GO; GO:0046034; P:ATP metabolic process; ISS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006096; P:glycolytic process; IEA:Ensembl.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; ISS:UniProtKB.
DR   GO; GO:0006487; P:protein N-linked glycosylation; ISS:UniProtKB.
DR   GO; GO:0014066; P:regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
//
ID   ENTP6_HUMAN             Reviewed;         484 AA.
AC   O75354; A6NCX6; D3DW49; Q5QPJ2; Q5QPJ5; Q7Z5B5; Q8N3H3; Q8TAS7;
AC   Q9UJD1;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 6;
DE            Short=NTPDase 6;
DE            EC=3.6.1.6;
DE   AltName: Full=CD39 antigen-like 2;
GN   Name=ENTPD6; Synonyms=CD39L2, IL6ST2;
DR   GO; GO:0008894; F:guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:Ensembl.
DR   GO; GO:0045134; F:uridine-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
//
ID   ENTP7_HUMAN             Reviewed;         604 AA.
AC   Q9NQZ7; B2RB83; B3KP21; D3DR64;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 7;
DE            Short=NTPDase 7;
DE            EC=3.6.1.-;
DE   AltName: Full=Lysosomal apyrase-like protein 1;
GN   Name=ENTPD7; Synonyms=LALP1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ENTP8_HUMAN             Reviewed;         495 AA.
AC   Q5MY95; A2BG17; Q6UVZ0;
DE   RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 8;
DE            Short=E-NTPDase 8;
DE            Short=NTPDase 8;
DE            Short=NTPDase8;
DE            EC=3.6.1.5;
GN   Name=ENTPD8; ORFNames=UNQ2492/PRO5779;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside-diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:Ensembl.
DR   GO; GO:0009133; P:nucleoside diphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0009124; P:nucleoside monophosphate biosynthetic process; IEA:Ensembl.
//
ID   ENW1_HUMAN              Reviewed;         538 AA.
AC   Q9UQF0; B2RPD4; O95244; O95245; Q8NHY7; Q9NRZ2; Q9NZG3;
DE   RecName: Full=HERV-W_7q21.2 provirus ancestral Env polyprotein;
DE   AltName: Full=Endogenous retrovirus group W member 1;
DE   AltName: Full=Env-W;
DE   AltName: Full=Envelope polyprotein gPr73;
DE   AltName: Full=Enverin;
DE   AltName: Full=HERV-7q Envelope protein;
DE   AltName: Full=HERV-W envelope protein;
DE   AltName: Full=Syncytin;
DE   AltName: Full=Syncytin-1;
DE   Contains:
DE     RecName: Full=Surface protein;
DE              Short=SU;
DE     AltName: Full=gp50;
DE   Contains:
DE     RecName: Full=Transmembrane protein;
DE              Short=TM;
DE     AltName: Full=gp24;
DE   Flags: Precursor;
GN   Name=ERVW-1; Synonyms=ERVWE1;
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006949; P:syncytium formation; TAS:ProtInc.
//
ID   ENY2_HUMAN              Reviewed;         101 AA.
AC   Q9NPA8; B2RE52; G3V117;
DE   RecName: Full=Transcription and mRNA export factor ENY2;
DE   AltName: Full=Enhancer of yellow 2 transcription factor homolog;
GN   Name=ENY2; ORFNames=DC6;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:UniProtKB-HAMAP.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IEA:UniProtKB-HAMAP.
//
ID   EOGT_HUMAN              Reviewed;         527 AA.
AC   Q5NDL2; A8K2U1; B4DFH5; L7X1M5; Q6MZY0; Q6P985; Q6ZTV0;
DE   RecName: Full=EGF domain-specific O-linked N-acetylglucosamine transferase;
DE            EC=2.4.1.255;
DE   AltName: Full=Extracellular O-linked N-acetylglucosamine transferase;
DE   Flags: Precursor;
GN   Name=EOGT; Synonyms=AER61, C3orf64, EOGT1;
DR   GO; GO:0016262; F:protein N-acetylglucosaminyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0006493; P:protein O-linked glycosylation; ISS:UniProtKB.
//
ID   EOMES_HUMAN             Reviewed;         686 AA.
AC   O95936; B7Z4I2; B7ZA51; G3XAI5; Q8TAZ2; Q9UPM7;
DE   RecName: Full=Eomesodermin homolog;
DE   AltName: Full=T-box brain protein 2;
DE            Short=T-brain-2;
DE            Short=TBR-2;
GN   Name=EOMES; Synonyms=TBR2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0010002; P:cardioblast differentiation; IEA:Ensembl.
DR   GO; GO:0002302; P:CD8-positive, alpha-beta T cell differentiation involved in immune response; IMP:UniProtKB.
DR   GO; GO:0060706; P:cell differentiation involved in embryonic placenta development; ISS:UniProtKB.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR   GO; GO:0001706; P:endoderm formation; ISS:UniProtKB.
DR   GO; GO:0001714; P:endodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; ISS:UniProtKB.
DR   GO; GO:0060809; P:mesodermal to mesenchymal transition involved in gastrulation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   EP15R_HUMAN             Reviewed;         864 AA.
AC   Q9UBC2; A2RRF3; A5PL29; B4DKA3;
DE   RecName: Full=Epidermal growth factor receptor substrate 15-like 1;
DE   AltName: Full=Eps15-related protein;
DE            Short=Eps15R;
GN   Name=EPS15L1; Synonyms=EPS15R;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
//
ID   EP2A2_HUMAN             Reviewed;         344 AA.
AC   B3EWF7;
DE   RecName: Full=Laforin, isoform 9;
GN   Name=EPM2A;
//
ID   EP300_HUMAN             Reviewed;        2414 AA.
AC   Q09472; B1AKC2;
DE   RecName: Full=Histone acetyltransferase p300;
DE            Short=p300 HAT;
DE            EC=2.3.1.48;
DE   AltName: Full=E1A-associated protein p300;
GN   Name=EP300; Synonyms=P300;
DR   GuidetoPHARMACOLOGY; 2735; -.
DR   GO; GO:0016407; F:acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.
DR   GO; GO:0003823; F:antigen binding; IEA:Ensembl.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IMP:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004468; F:lysine N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0043969; P:histone H2B acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0018393; P:internal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:BHF-UCL.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0045793; P:positive regulation of cell size; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0010560; P:positive regulation of glycoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0060298; P:positive regulation of sarcomere organization; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0065004; P:protein-DNA complex assembly; IEA:Ensembl.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060177; P:regulation of angiotensin metabolic process; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0090043; P:regulation of tubulin deacetylation; IDA:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0032025; P:response to cobalt ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   EP3A_HUMAN              Reviewed;         147 AA.
AC   Q14507; Q4KN33;
DE   RecName: Full=Epididymal secretory protein E3-alpha;
DE   AltName: Full=Human epididymis-specific protein 3-alpha;
DE            Short=HE3-alpha;
DE   Flags: Precursor;
GN   Name=EDDM3A; Synonyms=FAM12A, HE3A;
DR   GO; GO:0007321; P:sperm displacement; TAS:ProtInc.
//
ID   EP3B_HUMAN              Reviewed;         147 AA.
AC   P56851; A0PK89;
DE   RecName: Full=Epididymal secretory protein E3-beta;
DE   AltName: Full=Human epididymis-specific protein 3-beta;
DE            Short=HE3-beta;
DE   Flags: Precursor;
GN   Name=EDDM3B; Synonyms=FAM12B, HE3B; ORFNames=UNQ6412/PRO21187;
//
ID   EP400_HUMAN             Reviewed;        3159 AA.
AC   Q96L91; O15411; Q6P2F5; Q8N8Q7; Q8NE05; Q96JK7; Q9P230;
DE   RecName: Full=E1A-binding protein p400;
DE            EC=3.6.4.-;
DE   AltName: Full=CAG repeat protein 32;
DE   AltName: Full=Domino homolog;
DE            Short=hDomino;
DE   AltName: Full=Trinucleotide repeat-containing gene 12 protein;
DE   AltName: Full=p400 kDa SWI2/SNF2-related protein;
GN   Name=EP400; Synonyms=CAGH32, KIAA1498, KIAA1818, TNRC12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
//
ID   EPAB2_HUMAN             Reviewed;         278 AA.
AC   A6NDY0; A1L3B3; A2VDI2;
DE   RecName: Full=Embryonic polyadenylate-binding protein 2;
DE            Short=Embryonic poly(A)-binding protein 2;
DE            Short=ePABP-2;
DE            Short=ePABP2;
DE   AltName: Full=Embryonic poly(A)-binding protein type II;
DE   AltName: Full=Poly(A)-binding protein nuclear-like 1;
GN   Name=PABPN1L; Synonyms=EPABP2, PABPNL1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   EPAG_HUMAN              Reviewed;         149 AA.
AC   Q14236;
DE   RecName: Full=Early lymphoid activation gene protein;
GN   Name=EPAG;
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   EPAS1_HUMAN             Reviewed;         870 AA.
AC   Q99814; Q86VA2; Q99630;
DE   RecName: Full=Endothelial PAS domain-containing protein 1;
DE            Short=EPAS-1;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP2;
DE   AltName: Full=Class E basic helix-loop-helix protein 73;
DE            Short=bHLHe73;
DE   AltName: Full=HIF-1-alpha-like factor;
DE            Short=HLF;
DE   AltName: Full=Hypoxia-inducible factor 2-alpha;
DE            Short=HIF-2-alpha;
DE            Short=HIF2-alpha;
DE   AltName: Full=Member of PAS protein 2;
DE   AltName: Full=PAS domain-containing protein 2;
GN   Name=EPAS1; Synonyms=BHLHE73, HIF2A, MOP2, PASD2;
DR   GO; GO:0003677; F:DNA binding; IGI:MGI.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0048625; P:myoblast fate commitment; ISS:BHF-UCL.
DR   GO; GO:0042415; P:norepinephrine metabolic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   EPB42_HUMAN             Reviewed;         691 AA.
AC   P16452; Q4VB97;
DE   RecName: Full=Erythrocyte membrane protein band 4.2;
DE            Short=Erythrocyte protein 4.2;
DE            Short=P4.2;
GN   Name=EPB42; Synonyms=E42P;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW.
DR   GO; GO:0020027; P:hemoglobin metabolic process; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
//
ID   EPC1_HUMAN              Reviewed;         836 AA.
AC   Q9H2F5; B4DSC3; D3DRX7; Q5VW54; Q5VW56; Q5VW58; Q8NAQ4; Q8NE21;
AC   Q96LF4; Q96RR6; Q9H7T7;
DE   RecName: Full=Enhancer of polycomb homolog 1;
GN   Name=EPC1;
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:MGI.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:UniProtKB.
//
ID   EPC2_HUMAN              Reviewed;         807 AA.
AC   Q52LR7; B3KWT7; D3DP89; Q7L9J1; Q96RR7; Q9NUT8; Q9NVR1; Q9UFM9;
DE   RecName: Full=Enhancer of polycomb homolog 2;
DE   AltName: Full=EPC-like;
GN   Name=EPC2;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EPCAM_HUMAN             Reviewed;         314 AA.
AC   P16422; P18180; Q6FG26; Q6FG49; Q96C47; Q9UCD0;
DE   RecName: Full=Epithelial cell adhesion molecule;
DE            Short=Ep-CAM;
DE   AltName: Full=Adenocarcinoma-associated antigen;
DE   AltName: Full=Cell surface glycoprotein Trop-1;
DE   AltName: Full=Epithelial cell surface antigen;
DE   AltName: Full=Epithelial glycoprotein;
DE            Short=EGP;
DE   AltName: Full=Epithelial glycoprotein 314;
DE            Short=EGP314;
DE            Short=hEGP314;
DE   AltName: Full=KS 1/4 antigen;
DE   AltName: Full=KSA;
DE   AltName: Full=Major gastrointestinal tumor-associated protein GA733-2;
DE   AltName: Full=Tumor-associated calcium signal transducer 1;
DE   AltName: CD_antigen=CD326;
DE   Flags: Precursor;
GN   Name=EPCAM; Synonyms=GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:2000048; P:negative regulation of cell-cell adhesion mediated by cadherin; IDA:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProt.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProt.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IMP:UniProt.
DR   GO; GO:0048863; P:stem cell differentiation; IMP:UniProt.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   EPCR_HUMAN              Reviewed;         238 AA.
AC   Q9UNN8; B2RC04; Q14218; Q6IB56; Q96CB3; Q9ULX1;
DE   RecName: Full=Endothelial protein C receptor;
DE   AltName: Full=Activated protein C receptor;
DE            Short=APC receptor;
DE   AltName: Full=Endothelial cell protein C receptor;
DE   AltName: CD_antigen=CD201;
DE   Flags: Precursor;
GN   Name=PROCR; Synonyms=EPCR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0050819; P:negative regulation of coagulation; IMP:BHF-UCL.
//
ID   EPDR1_HUMAN             Reviewed;         224 AA.
AC   Q9UM22; A8K4C0; C9JYS3; Q06BL0; Q99M77;
DE   RecName: Full=Mammalian ependymin-related protein 1;
DE            Short=MERP-1;
DE   AltName: Full=Upregulated in colorectal cancer gene 1 protein;
DE   Flags: Precursor;
GN   Name=EPDR1; Synonyms=MERP1, UCC1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
//
ID   EPG5_HUMAN              Reviewed;        2579 AA.
AC   Q9HCE0; A2BDF3; Q9H8C8;
DE   RecName: Full=Ectopic P granules protein 5 homolog;
GN   Name=EPG5; Synonyms=KIAA1632;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   EPGN_HUMAN              Reviewed;         154 AA.
AC   Q6UW88; A1BMM3; A1BMM4; A1BMM5; A1BMM6; A1BMM7; A1BMM8; A8K090;
DE   RecName: Full=Epigen;
DE   AltName: Full=Epithelial mitogen;
DE            Short=EPG;
DE   Flags: Precursor;
GN   Name=EPGN; ORFNames=UNQ3072/PRO9904;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:HGNC.
DR   GO; GO:0008083; F:growth factor activity; IDA:HGNC.
DR   GO; GO:0004708; F:MAP kinase kinase activity; ISS:HGNC.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:HGNC.
DR   GO; GO:0001525; P:angiogenesis; IDA:HGNC.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:HGNC.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:HGNC.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:HGNC.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:HGNC.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:HGNC.
//
ID   EPHA1_HUMAN             Reviewed;         976 AA.
AC   P21709; A1L3V3; Q15405;
DE   RecName: Full=Ephrin type-A receptor 1;
DE            Short=hEpha1;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH tyrosine kinase;
DE   AltName: Full=EPH tyrosine kinase 1;
DE   AltName: Full=Erythropoietin-producing hepatoma receptor;
DE   AltName: Full=Tyrosine-protein kinase receptor EPH;
DE   Flags: Precursor;
GN   Name=EPHA1; Synonyms=EPH, EPHT, EPHT1;
DR   GuidetoPHARMACOLOGY; 1821; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.
//
ID   EPHA2_HUMAN             Reviewed;         976 AA.
AC   P29317; Q8N3Z2;
DE   RecName: Full=Ephrin type-A receptor 2;
DE            EC=2.7.10.1;
DE   AltName: Full=Epithelial cell kinase;
DE   AltName: Full=Tyrosine-protein kinase receptor ECK;
DE   Flags: Precursor;
GN   Name=EPHA2; Synonyms=ECK;
DR   GuidetoPHARMACOLOGY; 1822; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005003; F:ephrin receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0048320; P:axial mesoderm formation; IEA:Ensembl.
DR   GO; GO:0046849; P:bone remodeling; ISS:UniProtKB.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0070309; P:lens fiber cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0060035; P:notochord cell development; IEA:Ensembl.
DR   GO; GO:0014028; P:notochord formation; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0043491; P:protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0043535; P:regulation of blood vessel endothelial cell migration; ISS:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0010591; P:regulation of lamellipodium assembly; IMP:UniProtKB.
DR   GO; GO:0070848; P:response to growth factor; IMP:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   EPHA3_HUMAN             Reviewed;         983 AA.
AC   P29320; Q9H2V3; Q9H2V4;
DE   RecName: Full=Ephrin type-A receptor 3;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH-like kinase 4;
DE            Short=EK4;
DE            Short=hEK4;
DE   AltName: Full=HEK;
DE            Short=Human embryo kinase;
DE   AltName: Full=Tyrosine-protein kinase TYRO4;
DE   AltName: Full=Tyrosine-protein kinase receptor ETK1;
DE            Short=Eph-like tyrosine kinase 1;
DE   Flags: Precursor;
GN   Name=EPHA3; Synonyms=ETK, ETK1, HEK, TYRO4;
DR   GuidetoPHARMACOLOGY; 1823; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.
DR   GO; GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB.
//
ID   EPHA4_HUMAN             Reviewed;         986 AA.
AC   P54764; Q2M380;
DE   RecName: Full=Ephrin type-A receptor 4;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH-like kinase 8;
DE            Short=EK8;
DE            Short=hEK8;
DE   AltName: Full=Tyrosine-protein kinase TYRO1;
DE   AltName: Full=Tyrosine-protein kinase receptor SEK;
DE   Flags: Precursor;
GN   Name=EPHA4; Synonyms=HEK8, SEK, TYRO1;
DR   GuidetoPHARMACOLOGY; 1824; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0097161; F:DH domain binding; IDA:UniProtKB.
DR   GO; GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0042731; F:PH domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0021957; P:corticospinal tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.
DR   GO; GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.
DR   GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; ISS:UniProtKB.
DR   GO; GO:0048681; P:negative regulation of axon regeneration; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:2001108; P:positive regulation of Rho guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0048710; P:regulation of astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.
DR   GO; GO:0032317; P:regulation of Rap GTPase activity; ISS:UniProtKB.
//
ID   EPHA5_HUMAN             Reviewed;        1037 AA.
AC   P54756; Q7Z3F2;
DE   RecName: Full=Ephrin type-A receptor 5;
DE            EC=2.7.10.1;
DE   AltName: Full=Brain-specific kinase;
DE   AltName: Full=EPH homology kinase 1;
DE            Short=EHK-1;
DE   AltName: Full=EPH-like kinase 7;
DE            Short=EK7;
DE            Short=hEK7;
DE   Flags: Precursor;
GN   Name=EPHA5; Synonyms=BSK, EHK1, HEK7, TYRO4;
DR   GuidetoPHARMACOLOGY; 1825; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005003; F:ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021766; P:hippocampus development; ISS:UniProtKB.
DR   GO; GO:0051964; P:negative regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEP:UniProtKB.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.
//
ID   EPHA6_HUMAN             Reviewed;        1036 AA.
AC   Q9UF33; D6RAL5;
DE   RecName: Full=Ephrin type-A receptor 6;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH homology kinase 2;
DE            Short=EHK-2;
DE   AltName: Full=EPH-like kinase 12;
DE            Short=EK12;
DE   Flags: Precursor;
GN   Name=EPHA6; Synonyms=EHK2, HEK12;
DR   GuidetoPHARMACOLOGY; 1826; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005003; F:ephrin receptor activity; IEA:InterPro.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
//
ID   EPHA7_HUMAN             Reviewed;         998 AA.
AC   Q15375; A0AUX7; B2R8W1; B7ZLJ9; B7ZLK0; Q59G40; Q5VTU0; Q8N368;
AC   Q9H124;
DE   RecName: Full=Ephrin type-A receptor 7;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH homology kinase 3;
DE            Short=EHK-3;
DE   AltName: Full=EPH-like kinase 11;
DE            Short=EK11;
DE            Short=hEK11;
DE   Flags: Precursor;
GN   Name=EPHA7; Synonyms=EHK3, HEK11;
DR   GuidetoPHARMACOLOGY; 1827; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008046; F:axon guidance receptor activity; ISS:UniProtKB.
DR   GO; GO:0045499; F:chemorepellent activity; ISS:UniProtKB.
DR   GO; GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:GOC.
DR   GO; GO:0016310; P:phosphorylation; ISS:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031952; P:regulation of protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
//
ID   EPHA8_HUMAN             Reviewed;        1005 AA.
AC   P29322; Q6IN80; Q8IUX6; Q9NUA9; Q9P269;
DE   RecName: Full=Ephrin type-A receptor 8;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH- and ELK-related kinase;
DE   AltName: Full=EPH-like kinase 3;
DE            Short=EK3;
DE            Short=hEK3;
DE   AltName: Full=Tyrosine-protein kinase receptor EEK;
DE   Flags: Precursor;
GN   Name=EPHA8; Synonyms=EEK, HEK3, KIAA1459;
DR   GuidetoPHARMACOLOGY; 1828; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005004; F:GPI-linked ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0016322; P:neuron remodeling; ISS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.
DR   GO; GO:0006929; P:substrate-dependent cell migration; ISS:UniProtKB.
//
ID   EPHAA_HUMAN             Reviewed;        1008 AA.
AC   Q5JZY3; A4FU89; J3KPB5; Q6NW42;
DE   RecName: Full=Ephrin type-A receptor 10;
DE            EC=2.7.10.1;
DE   Flags: Precursor;
GN   Name=EPHA10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005003; F:ephrin receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:GOC.
//
ID   EPHB1_HUMAN             Reviewed;         984 AA.
AC   P54762; A8K593; O43569; O95142; O95143; Q0VG87;
DE   RecName: Full=Ephrin type-B receptor 1;
DE            EC=2.7.10.1;
DE   AltName: Full=ELK;
DE   AltName: Full=EPH tyrosine kinase 2;
DE   AltName: Full=EPH-like kinase 6;
DE            Short=EK6;
DE            Short=hEK6;
DE   AltName: Full=Neuronally-expressed EPH-related tyrosine kinase;
DE            Short=NET;
DE   AltName: Full=Tyrosine-protein kinase receptor EPH-2;
DE   Flags: Precursor;
GN   Name=EPHB1; Synonyms=ELK, EPHT2, HEK6, NET;
DR   GuidetoPHARMACOLOGY; 1830; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008046; F:axon guidance receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0031589; P:cell-substrate adhesion; IDA:UniProtKB.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; ISS:UniProtKB.
DR   GO; GO:0060996; P:dendritic spine development; ISS:UniProtKB.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
DR   GO; GO:0021631; P:optic nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB.
//
ID   EPHB2_HUMAN             Reviewed;        1055 AA.
AC   P29323; O43477; Q5T0U6; Q5T0U7; Q5T0U8;
DE   RecName: Full=Ephrin type-B receptor 2;
DE            EC=2.7.10.1;
DE   AltName: Full=Developmentally-regulated Eph-related tyrosine kinase;
DE   AltName: Full=ELK-related tyrosine kinase;
DE   AltName: Full=EPH tyrosine kinase 3;
DE   AltName: Full=EPH-like kinase 5;
DE            Short=EK5;
DE            Short=hEK5;
DE   AltName: Full=Renal carcinoma antigen NY-REN-47;
DE   AltName: Full=Tyrosine-protein kinase TYRO5;
DE   AltName: Full=Tyrosine-protein kinase receptor EPH-3;
DE   Flags: Precursor;
GN   Name=EPHB2; Synonyms=DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5;
DR   GuidetoPHARMACOLOGY; 1831; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008046; F:axon guidance receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0005005; F:transmembrane-ephrin receptor activity; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0007413; P:axonal fasciculation; ISS:UniProtKB.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0071679; P:commissural neuron axon guidance; ISS:UniProtKB.
DR   GO; GO:0022038; P:corpus callosum development; ISS:UniProtKB.
DR   GO; GO:0060996; P:dendritic spine development; ISS:UniProtKB.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0021631; P:optic nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; ISS:UniProtKB.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0050878; P:regulation of body fluid levels; ISS:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0001655; P:urogenital system development; ISS:UniProtKB.
//
ID   EPHB3_HUMAN             Reviewed;         998 AA.
AC   P54753; Q7Z740;
DE   RecName: Full=Ephrin type-B receptor 3;
DE            EC=2.7.10.1;
DE   AltName: Full=EPH-like tyrosine kinase 2;
DE            Short=EPH-like kinase 2;
DE   AltName: Full=Embryonic kinase 2;
DE            Short=EK2;
DE            Short=hEK2;
DE   AltName: Full=Tyrosine-protein kinase TYRO6;
DE   Flags: Precursor;
GN   Name=EPHB3; Synonyms=ETK2, HEK2, TYRO6;
DR   GuidetoPHARMACOLOGY; 1832; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008046; F:axon guidance receptor activity; IEA:Ensembl.
DR   GO; GO:0005003; F:ephrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0007413; P:axonal fasciculation; ISS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0022038; P:corpus callosum development; ISS:UniProtKB.
DR   GO; GO:0060996; P:dendritic spine development; ISS:UniProtKB.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048546; P:digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0048538; P:thymus development; ISS:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; ISS:UniProtKB.
//
ID   EPHB4_HUMAN             Reviewed;         987 AA.
AC   P54760; Q9BTA5; Q9BXP0;
DE   RecName: Full=Ephrin type-B receptor 4;
DE            EC=2.7.10.1;
DE   AltName: Full=Hepatoma transmembrane kinase;
DE   AltName: Full=Tyrosine-protein kinase TYRO11;
DE   Flags: Precursor;
GN   Name=EPHB4; Synonyms=HTK, MYK1, TYRO11;
DR   GuidetoPHARMACOLOGY; 1833; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005003; F:ephrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
//
ID   EPHB6_HUMAN             Reviewed;        1021 AA.
AC   O15197; A4D2I7; A8CDT5; D3DXD3; Q2TB23; Q2TB24;
DE   RecName: Full=Ephrin type-B receptor 6;
DE   AltName: Full=HEP;
DE   AltName: Full=Tyrosine-protein kinase-defective receptor EPH-6;
DE   Flags: Precursor;
GN   Name=EPHB6;
DR   GuidetoPHARMACOLOGY; 1834; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005003; F:ephrin receptor activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0035898; P:parathyroid hormone secretion; IEA:Ensembl.
//
ID   EPHX3_HUMAN             Reviewed;         360 AA.
AC   Q9H6B9; A3KMR3;
DE   RecName: Full=Epoxide hydrolase 3;
DE            EC=3.3.-.-;
DE   AltName: Full=Abhydrolase domain-containing protein 9;
DE   Flags: Precursor;
GN   Name=EPHX3; Synonyms=ABHD9;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   EPHX4_HUMAN             Reviewed;         362 AA.
AC   Q8IUS5; Q8NCC6;
DE   RecName: Full=Epoxide hydrolase 4;
DE            EC=3.3.-.-;
DE   AltName: Full=Abhydrolase domain-containing protein 7;
DE   AltName: Full=Epoxide hydrolase-related protein;
GN   Name=EPHX4; Synonyms=ABHD7, EPHXRP;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   EPIPL_HUMAN             Reviewed;        5090 AA.
AC   P58107; Q76E58; Q9NSU9;
DE   RecName: Full=Epiplakin;
DE   AltName: Full=450 kDa epidermal antigen;
GN   Name=EPPK1; Synonyms=EPIPL;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   EPM2A_HUMAN             Reviewed;         331 AA.
AC   O95278; B3KMU5; B4DRZ2; O95483; Q5T3F5; Q6IS15; Q8IU96; Q8IX24;
AC   Q8IX25; Q9BS66; Q9UEN2;
DE   RecName: Full=Laforin;
DE            EC=3.1.3.-;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=Glucan phosphatase;
DE   AltName: Full=Lafora PTPase;
DE            Short=LAFPTPase;
GN   Name=EPM2A;
DR   GO; GO:0019203; F:carbohydrate phosphatase activity; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:2001070; F:starch binding; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; NAS:UniProtKB.
DR   GO; GO:0046959; P:habituation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   EPMIP_HUMAN             Reviewed;         607 AA.
AC   Q7L775; O94866; Q9H3L3;
DE   RecName: Full=EPM2A-interacting protein 1;
DE   AltName: Full=Laforin-interacting protein;
GN   Name=EPM2AIP1; Synonyms=KIAA0766; ORFNames=My007;
//
ID   EPN1_HUMAN              Reviewed;         576 AA.
AC   Q9Y6I3; Q86ST3; Q9HA18;
DE   RecName: Full=Epsin-1;
DE   AltName: Full=EH domain-binding mitotic phosphoprotein;
DE   AltName: Full=EPS-15-interacting protein 1;
GN   Name=EPN1;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
//
ID   EPN2_HUMAN              Reviewed;         641 AA.
AC   O95208; A8MTV8; B3KRX8; E9PBC2; O95207; Q52LD0; Q9H7Z2; Q9UPT7;
DE   RecName: Full=Epsin-2;
DE   AltName: Full=EPS-15-interacting protein 2;
GN   Name=EPN2; Synonyms=KIAA1065;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
//
ID   EPN3_HUMAN              Reviewed;         632 AA.
AC   Q9H201; A8K6J3; A8KAB2; Q9BVN6; Q9NWK2;
DE   RecName: Full=Epsin-3;
DE   AltName: Full=EPS-15-interacting protein 3;
GN   Name=EPN3;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
//
ID   EPN4_HUMAN              Reviewed;         625 AA.
AC   Q14677; B7Z6F8; D3DQJ6; Q8NAF1; Q96E05;
DE   RecName: Full=Clathrin interactor 1;
DE   AltName: Full=Clathrin-interacting protein localized in the trans-Golgi region;
DE            Short=Clint;
DE   AltName: Full=Enthoprotin;
DE   AltName: Full=Epsin-4;
DE   AltName: Full=Epsin-related protein;
DE            Short=EpsinR;
GN   Name=CLINT1; Synonyms=ENTH, EPN4, EPNR, KIAA0171;
DR   GO; GO:0030276; F:clathrin binding; IPI:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
//
ID   EPOR_HUMAN              Reviewed;         508 AA.
AC   P19235; B2RCG4; Q15443; Q2M205;
DE   RecName: Full=Erythropoietin receptor;
DE            Short=EPO-R;
DE   Flags: Precursor;
GN   Name=EPOR;
DR   GuidetoPHARMACOLOGY; 1718; -.
DR   GO; GO:0004900; F:erythropoietin receptor activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0038162; P:erythropoietin-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   EPO_HUMAN               Reviewed;         193 AA.
AC   P01588; Q2M2L6; Q549U2; Q9UDZ0; Q9UEZ5; Q9UHA0;
DE   RecName: Full=Erythropoietin;
DE   AltName: INN=Epoetin;
DE   Flags: Precursor;
GN   Name=EPO;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030295; F:protein kinase activator activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; NAS:ProtInc.
DR   GO; GO:0071474; P:cellular hyperosmotic response; IDA:BHF-UCL.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010523; P:negative regulation of calcium ion transport into cytosol; IDA:BHF-UCL.
DR   GO; GO:2001258; P:negative regulation of cation channel activity; IDA:BHF-UCL.
DR   GO; GO:1902251; P:negative regulation of erythrocyte apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902219; P:negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; IDA:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   EPPI_HUMAN              Reviewed;         133 AA.
AC   O95925; A6PVD6; Q86TP9; Q96SD7; Q9HD30;
DE   RecName: Full=Eppin;
DE   AltName: Full=Cancer/testis antigen 71;
DE            Short=CT71;
DE   AltName: Full=Epididymal protease inhibitor;
DE   AltName: Full=Protease inhibitor WAP7;
DE   AltName: Full=Serine protease inhibitor-like with Kunitz and WAP domains 1;
DE   AltName: Full=WAP four-disulfide core domain protein 7;
DE   Flags: Precursor;
GN   Name=EPPIN; Synonyms=SPINLW1, WAP7, WFDC7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:UniProtKB.
//
ID   EPS15_HUMAN             Reviewed;         896 AA.
AC   P42566; B2R8J7; D3DPJ2; Q5SRH4;
DE   RecName: Full=Epidermal growth factor receptor substrate 15;
DE            Short=Protein Eps15;
DE   AltName: Full=Protein AF-1p;
GN   Name=EPS15; Synonyms=AF1P;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0048268; P:clathrin coat assembly; IDA:BHF-UCL.
DR   GO; GO:0032456; P:endocytic recycling; IC:BHF-UCL.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016050; P:vesicle organization; TAS:UniProtKB.
//
ID   EPS8_HUMAN              Reviewed;         822 AA.
AC   Q12929; A6NMC3; A8K6W2; A8KA66; Q8N6J0;
DE   RecName: Full=Epidermal growth factor receptor kinase substrate 8;
GN   Name=EPS8;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048365; F:Rac GTPase binding; ISS:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0051764; P:actin crosslink formation; ISS:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
DR   GO; GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB.
DR   GO; GO:0070358; P:actin polymerization-dependent cell motility; ISS:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0051016; P:barbed-end actin filament capping; ISS:UniProtKB.
DR   GO; GO:0048149; P:behavioral response to ethanol; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0036336; P:dendritic cell migration; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0010458; P:exit from mitosis; ISS:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0030832; P:regulation of actin filament length; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   EPT1_HUMAN              Reviewed;         397 AA.
AC   Q9C0D9; Q63ZE3;
DE   RecName: Full=Ethanolaminephosphotransferase 1;
DE            Short=hEPT1;
DE            EC=2.7.8.1;
DE   AltName: Full=Selenoprotein I;
DE            Short=SelI;
GN   Name=EPT1; Synonyms=KIAA1724, SELI;
DR   GO; GO:0004307; F:ethanolaminephosphotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   EPYC_HUMAN              Reviewed;         322 AA.
AC   Q99645; A8K3M7; Q8NEJ5;
DE   RecName: Full=Epiphycan;
DE   AltName: Full=Dermatan sulfate proteoglycan 3;
DE   AltName: Full=Proteoglycan-Lb;
DE            Short=PG-Lb;
DE   AltName: Full=Small chondroitin/dermatan sulfate proteoglycan;
DE   Flags: Precursor;
GN   Name=EPYC; Synonyms=DSPG3, PGLB, SLRR3B;
DR   GO; GO:0005539; F:glycosaminoglycan binding; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   EQTN_HUMAN              Reviewed;         294 AA.
AC   Q9NQ60; B2RPB3; B7ZMK1; Q5TCU1; Q96L22;
DE   RecName: Full=Equatorin;
DE   AltName: Full=Acrosome formation-associated factor;
DE   Flags: Precursor;
GN   Name=EQTN; Synonyms=AFAF, C9orf11;
DR   GO; GO:0060478; P:acrosomal vesicle exocytosis; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IEA:Ensembl.
//
ID   ER6L2_HUMAN             Reviewed;        1561 AA.
AC   Q5T890; A4D997; B2RTP8; Q49AM9; Q5T892; Q8N663; Q8N9D0; Q9NPM7;
DE   RecName: Full=DNA excision repair protein ERCC-6-like 2;
DE            EC=3.6.4.-;
DE   AltName: Full=DNA repair and recombination protein RAD26-like;
GN   Name=ERCC6L2; Synonyms=C9orf102, RAD26L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
//
ID   ERAL1_HUMAN             Reviewed;         437 AA.
AC   O75616; B3KN21; C9JEC6; O75617; Q8WUY4; Q96LE2; Q96TC0;
DE   RecName: Full=GTPase Era, mitochondrial;
DE            Short=H-ERA;
DE            Short=hERA;
DE   AltName: Full=Conserved ERA-like GTPase;
DE            Short=CEGA;
DE   AltName: Full=ERA-W;
DE   AltName: Full=ERA-like protein 1;
DE   Flags: Precursor;
GN   Name=ERAL1; Synonyms=HERA;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IDA:UniProtKB.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IMP:UniProtKB.
//
ID   ERAP1_HUMAN             Reviewed;         941 AA.
AC   Q9NZ08; O60278; Q6UWY6; Q8NEL4; Q8TAD0; Q9UHF8; Q9UKY2;
DE   RecName: Full=Endoplasmic reticulum aminopeptidase 1;
DE            EC=3.4.11.-;
DE   AltName: Full=ARTS-1;
DE   AltName: Full=Adipocyte-derived leucine aminopeptidase;
DE            Short=A-LAP;
DE   AltName: Full=Aminopeptidase PILS;
DE   AltName: Full=Puromycin-insensitive leucyl-specific aminopeptidase;
DE            Short=PILS-AP;
DE   AltName: Full=Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator;
GN   Name=ERAP1; Synonyms=APPILS, ARTS1, KIAA0525; ORFNames=UNQ584/PRO1154;
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005151; F:interleukin-1, Type II receptor binding; TAS:HGNC.
DR   GO; GO:0005138; F:interleukin-6 receptor binding; IPI:UniProtKB.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; TAS:HGNC.
DR   GO; GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; NAS:UniProtKB.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0045444; P:fat cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; NAS:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IEP:BHF-UCL.
//
ID   ERAP2_HUMAN             Reviewed;         960 AA.
AC   Q6P179; Q7Z5K1; Q8TD32; Q8WVJ4; Q9HBX2;
DE   RecName: Full=Endoplasmic reticulum aminopeptidase 2;
DE            EC=3.4.11.-;
DE   AltName: Full=Leukocyte-derived arginine aminopeptidase;
DE            Short=L-RAP;
GN   Name=ERAP2; Synonyms=LRAP;
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:HGNC.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; TAS:HGNC.
DR   GO; GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; TAS:HGNC.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:HGNC.
//
ID   ERAS1_HUMAN             Reviewed;          84 AA.
AC   P0C838;
DE   RecName: Full=Putative uncharacterized protein encoded by ERICH1-AS1;
DE   AltName: Full=ERICH1 antisense RNA 1;
DE   AltName: Full=ERICH1 antisense gene protein 1;
DE   AltName: Full=Putative DAP-2 like protein;
GN   Name=ERICH1-AS1; Synonyms=C8orf68;
//
ID   ERB1_HUMAN              Reviewed;         514 AA.
AC   P60509;
DE   RecName: Full=HERV-R(b)_3p24.3 provirus ancestral Env polyprotein;
DE   AltName: Full=Endogenous retrovirus group PABLB member 1;
DE   AltName: Full=Envelope polyprotein;
DE   AltName: Full=HERV-R(b) Env protein;
DE   Includes:
DE     RecName: Full=Surface protein domain;
DE              Short=SU;
DE   Includes:
DE     RecName: Full=Transmembrane protein domain;
DE              Short=TM;
DE   Flags: Precursor;
GN   Name=ERVPABLB-1;
//
ID   ERBB2_HUMAN             Reviewed;        1255 AA.
AC   P04626; B2RZG3; B4DHN3; Q14256; Q6LDV1; Q9UMK4;
DE   RecName: Full=Receptor tyrosine-protein kinase erbB-2;
DE            EC=2.7.10.1;
DE   AltName: Full=Metastatic lymph node gene 19 protein;
DE            Short=MLN 19;
DE   AltName: Full=Proto-oncogene Neu;
DE   AltName: Full=Proto-oncogene c-ErbB-2;
DE   AltName: Full=Tyrosine kinase-type cell surface receptor HER2;
DE   AltName: Full=p185erbB2;
DE   AltName: CD_antigen=CD340;
DE   Flags: Precursor;
GN   Name=ERBB2; Synonyms=HER2, MLN19, NEU, NGL;
DR   GuidetoPHARMACOLOGY; 2019; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005006; F:epidermal growth factor-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0043125; F:ErbB-3 class receptor binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; NAS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0001042; F:RNA polymerase I core binding; IDA:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:MGI.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030879; P:mammary gland development; TAS:UniProtKB.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0033088; P:negative regulation of immature T cell proliferation in thymus; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IMP:UniProtKB.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0045765; P:regulation of angiogenesis; NAS:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; TAS:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; IDA:BHF-UCL.
//
ID   ERBB3_HUMAN             Reviewed;        1342 AA.
AC   P21860; A8K6L6; B4DIK7; B4DV32; E9PDT8; Q9BUD7;
DE   RecName: Full=Receptor tyrosine-protein kinase erbB-3;
DE            EC=2.7.10.1;
DE   AltName: Full=Proto-oncogene-like protein c-ErbB-3;
DE   AltName: Full=Tyrosine kinase-type cell surface receptor HER3;
DE   Flags: Precursor;
GN   Name=ERBB3; Synonyms=HER3;
DR   GuidetoPHARMACOLOGY; 1798; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:BHF-UCL.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IDA:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; ISS:BHF-UCL.
DR   GO; GO:0021545; P:cranial nerve development; ISS:BHF-UCL.
DR   GO; GO:0003197; P:endocardial cushion development; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0051048; P:negative regulation of secretion; IDA:BHF-UCL.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IDA:BHF-UCL.
DR   GO; GO:0051402; P:neuron apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007422; P:peripheral nervous system development; ISS:BHF-UCL.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; TAS:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IMP:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0014037; P:Schwann cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; NAS:BHF-UCL.
//
ID   ERBB4_HUMAN             Reviewed;        1308 AA.
AC   Q15303; B7ZLD7; B7ZLE2; B7ZLE3; Q2M1W1; Q59EW4;
DE   RecName: Full=Receptor tyrosine-protein kinase erbB-4;
DE            EC=2.7.10.1;
DE   AltName: Full=Proto-oncogene-like protein c-ErbB-4;
DE   AltName: Full=Tyrosine kinase-type cell surface receptor HER4;
DE   AltName: Full=p180erbB4;
DE   Contains:
DE     RecName: Full=ERBB4 intracellular domain;
DE              Short=4ICD;
DE              Short=E4ICD;
DE     AltName: Full=s80HER4;
DE   Flags: Precursor;
GN   Name=ERBB4; Synonyms=HER4;
DR   GuidetoPHARMACOLOGY; 1799; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0061026; P:cardiac muscle tissue regeneration; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0021551; P:central nervous system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IMP:UniProtKB.
DR   GO; GO:0060749; P:mammary gland alveolus development; ISS:UniProtKB.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0021889; P:olfactory bulb interneuron differentiation; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; TAS:UniProtKB.
DR   GO; GO:2000366; P:positive regulation of STAT protein import into nucleus; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:UniProtKB.
//
ID   ERC2_HUMAN              Reviewed;         957 AA.
AC   O15083; Q2T9F6; Q86TK4;
DE   RecName: Full=ERC protein 2;
GN   Name=ERC2; Synonyms=KIAA0378;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   ERC6L_HUMAN             Reviewed;        1250 AA.
AC   Q2NKX8; Q8NCI1; Q96H93; Q9NXQ8;
DE   RecName: Full=DNA excision repair protein ERCC-6-like;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase ERCC6-like;
DE   AltName: Full=PLK1-interacting checkpoint helicase;
DE   AltName: Full=Tumor antigen BJ-HCC-15;
GN   Name=ERCC6L; Synonyms=PICH;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   ERCC1_HUMAN             Reviewed;         297 AA.
AC   P07992; B2RC01; B3KRR0; Q7Z7F5; Q96S40;
DE   RecName: Full=DNA excision repair protein ERCC-1;
GN   Name=ERCC1;
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IGI:MGI.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0006312; P:mitotic recombination; IMP:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0032205; P:negative regulation of telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IDA:MGI.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IMP:UniProtKB.
DR   GO; GO:0006296; P:nucleotide-excision repair, DNA incision, 5'-to lesion; IMP:UniProtKB.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0035166; P:post-embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0000720; P:pyrimidine dimer repair by nucleotide-excision repair; IEA:Ensembl.
DR   GO; GO:0001302; P:replicative cell aging; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0009744; P:response to sucrose; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006949; P:syncytium formation; IEA:Ensembl.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0009650; P:UV protection; IEA:Ensembl.
//
ID   ERCC5_HUMAN             Reviewed;        1186 AA.
AC   P28715; A6NGT4; Q5JUS4; Q5JUS5; Q7Z2V3; Q8IZL6; Q8N1B7; Q9HD59;
AC   Q9HD60;
DE   RecName: Full=DNA repair protein complementing XP-G cells;
DE            EC=3.1.-.-;
DE   AltName: Full=DNA excision repair protein ERCC-5;
DE   AltName: Full=Xeroderma pigmentosum group G-complementing protein;
GN   Name=ERCC5; Synonyms=ERCM2, XPG, XPGC;
DR   GO; GO:0000405; F:bubble DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; TAS:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0010225; P:response to UV-C; IMP:UniProtKB.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0009650; P:UV protection; IGI:MGI.
//
ID   ERCC8_HUMAN             Reviewed;         396 AA.
AC   Q13216; B2RB64; Q6FHX5; Q96GB9;
DE   RecName: Full=DNA excision repair protein ERCC-8;
DE   AltName: Full=Cockayne syndrome WD repeat protein CSA;
GN   Name=ERCC8; Synonyms=CKN1, CSA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.
//
ID   ERD21_HUMAN             Reviewed;         212 AA.
AC   P24390; B2R6N4; Q54A39;
DE   RecName: Full=ER lumen protein-retaining receptor 1;
DE   AltName: Full=KDEL endoplasmic reticulum protein retention receptor 1;
DE            Short=KDEL receptor 1;
DE   AltName: Full=Putative MAPK-activating protein PM23;
GN   Name=KDELR1; Synonyms=ERD2.1;
DR   GO; GO:0005046; F:KDEL sequence binding; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0006621; P:protein retention in ER lumen; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ERCC2_HUMAN             Reviewed;         760 AA.
AC   P18074; Q2TB78; Q2YDY2; Q7KZU6; Q8N721;
DE   RecName: Full=TFIIH basal transcription factor complex helicase XPD subunit;
DE            EC=3.6.4.12;
DE   AltName: Full=Basic transcription factor 2 80 kDa subunit;
DE            Short=BTF2 p80;
DE   AltName: Full=CXPD;
DE   AltName: Full=DNA excision repair protein ERCC-2;
DE   AltName: Full=DNA repair protein complementing XP-D cells;
DE   AltName: Full=TFIIH basal transcription factor complex 80 kDa subunit;
DE            Short=TFIIH 80 kDa subunit;
DE            Short=TFIIH p80;
DE   AltName: Full=Xeroderma pigmentosum group D-complementing protein;
GN   Name=ERCC2; Synonyms=XPD, XPDC;
DR   GO; GO:0000441; ?:?; IEA:Ensembl.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0032289; P:central nervous system myelin formation; IEA:Ensembl.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0040016; P:embryonic cleavage; IEA:Ensembl.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035315; P:hair cell differentiation; IMP:UniProtKB.
DR   GO; GO:0048820; P:hair follicle maturation; IEA:Ensembl.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; NAS:UniProtKB.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0033683; P:nucleotide-excision repair, DNA incision; IMP:UniProtKB.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:1901990; P:regulation of mitotic cell cycle phase transition; IMP:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IDA:UniProtKB.
DR   GO; GO:0009650; P:UV protection; IGI:MGI.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ERCC3_HUMAN             Reviewed;         782 AA.
AC   P19447; Q53QM0;
DE   RecName: Full=TFIIH basal transcription factor complex helicase XPB subunit;
DE            EC=3.6.4.12;
DE   AltName: Full=Basic transcription factor 2 89 kDa subunit;
DE            Short=BTF2 p89;
DE   AltName: Full=DNA excision repair protein ERCC-3;
DE   AltName: Full=DNA repair protein complementing XP-B cells;
DE   AltName: Full=TFIIH basal transcription factor complex 89 kDa subunit;
DE            Short=TFIIH 89 kDa subunit;
DE            Short=TFIIH p89;
DE   AltName: Full=Xeroderma pigmentosum group B-complementing protein;
GN   Name=ERCC3; Synonyms=XPB, XPBC;
DR   GO; GO:0000441; ?:?; IEA:Ensembl.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:Ensembl.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; NAS:UniProtKB.
DR   GO; GO:0032564; F:dATP binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:Ensembl.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IDA:MGI.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0006265; P:DNA topological change; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035315; P:hair cell differentiation; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0000717; P:nucleotide-excision repair, DNA duplex unwinding; IMP:UniProtKB.
DR   GO; GO:0033683; P:nucleotide-excision repair, DNA incision; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:1901990; P:regulation of mitotic cell cycle phase transition; IMP:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IMP:UniProtKB.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IDA:UniProtKB.
DR   GO; GO:0009650; P:UV protection; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   ERD22_HUMAN             Reviewed;         212 AA.
AC   P33947; A4D2P4; Q6IPC5; Q96E30;
DE   RecName: Full=ER lumen protein-retaining receptor 2;
DE   AltName: Full=ERD2-like protein 1;
DE            Short=ELP-1;
DE   AltName: Full=KDEL endoplasmic reticulum protein retention receptor 2;
DE            Short=KDEL receptor 2;
GN   Name=KDELR2; Synonyms=ERD2.2;
DR   GO; GO:0005046; F:KDEL sequence binding; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0006621; P:protein retention in ER lumen; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ERCC6_HUMAN             Reviewed;        1493 AA.
AC   Q03468; D3DX94; Q5W0L9;
DE   RecName: Full=DNA excision repair protein ERCC-6;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase ERCC6;
DE   AltName: Full=Cockayne syndrome protein CSB;
GN   Name=ERCC6; Synonyms=CSB;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007256; P:activation of JNKK activity; IEA:Ensembl.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006284; P:base-excision repair; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:Ensembl.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0000303; P:response to superoxide; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0010224; P:response to UV-B; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.
//
ID   ERD23_HUMAN             Reviewed;         214 AA.
AC   O43731; A8K7T7; B8ZZ26; O95557; Q4V750; Q4V767; Q53FP4; Q53GK1;
DE   RecName: Full=ER lumen protein-retaining receptor 3;
DE   AltName: Full=KDEL endoplasmic reticulum protein retention receptor 3;
DE            Short=KDEL receptor 3;
GN   Name=KDELR3;
DR   GO; GO:0046923; F:ER retention sequence binding; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006621; P:protein retention in ER lumen; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   EREG_HUMAN              Reviewed;         169 AA.
AC   O14944; B2RC66; Q6FH69;
DE   RecName: Full=Proepiregulin;
DE   Contains:
DE     RecName: Full=Epiregulin;
DE              Short=EPR;
DE   Flags: Precursor;
GN   Name=EREG;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007143; P:female meiotic division; ISS:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030216; P:keratinocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0043616; P:keratinocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0042700; P:luteinizing hormone signaling pathway; ISS:UniProtKB.
DR   GO; GO:0009299; P:mRNA transcription; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; TAS:UniProtKB.
DR   GO; GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001556; P:oocyte maturation; ISS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:UniProtKB.
DR   GO; GO:0001550; P:ovarian cumulus expansion; ISS:UniProtKB.
DR   GO; GO:0030728; P:ovulation; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042108; P:positive regulation of cytokine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; ISS:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; ISS:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0045089; P:positive regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0048160; P:primary follicle stage; ISS:UniProtKB.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; TAS:UniProtKB.
//
ID   ERF1_HUMAN              Reviewed;         437 AA.
AC   P62495; B2R6B4; D3DQC1; P46055; Q5M7Z7;
DE   RecName: Full=Eukaryotic peptide chain release factor subunit 1;
DE            Short=Eukaryotic release factor 1;
DE            Short=eRF1;
DE   AltName: Full=Protein Cl1;
DE   AltName: Full=TB3-1;
GN   Name=ETF1; Synonyms=ERF1, RF1, SUP45L1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; TAS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003747; F:translation release factor activity; TAS:UniProtKB.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
DR   GO; GO:0008079; F:translation termination factor activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006479; P:protein methylation; IDA:MGI.
DR   GO; GO:0006449; P:regulation of translational termination; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
//
ID   ERF3A_HUMAN             Reviewed;         499 AA.
AC   P15170; J3KQG6; Q96GF2;
DE   RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit ERF3A;
DE            Short=Eukaryotic peptide chain release factor subunit 3a;
DE            Short=eRF3a;
DE   AltName: Full=G1 to S phase transition protein 1 homolog;
GN   Name=GSPT1; Synonyms=ERF3A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003747; F:translation release factor activity; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:UniProtKB.
DR   GO; GO:0006479; P:protein methylation; IDA:MGI.
DR   GO; GO:0006415; P:translational termination; IMP:GOC.
//
ID   ERF3B_HUMAN             Reviewed;         628 AA.
AC   Q8IYD1; Q9H909; Q9NVY0; Q9NY44;
DE   RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit ERF3B;
DE            Short=Eukaryotic peptide chain release factor subunit 3b;
DE            Short=eRF3b;
DE   AltName: Full=G1 to S phase transition protein 2 homolog;
GN   Name=GSPT2; Synonyms=ERF3B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
//
ID   ERF_HUMAN               Reviewed;         548 AA.
AC   P50548; B2RAP1; Q59G38; Q9UPI7;
DE   RecName: Full=ETS domain-containing transcription factor ERF;
DE   AltName: Full=Ets2 repressor factor;
DE   AltName: Full=PE-2;
GN   Name=ERF;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0060710; P:chorio-allantoic fusion; IEA:Ensembl.
DR   GO; GO:0010668; P:ectodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
//
ID   ERG1_HUMAN              Reviewed;         574 AA.
AC   Q14534; Q9UEK6;
DE   RecName: Full=Squalene monooxygenase;
DE            EC=1.14.13.132;
DE   AltName: Full=Squalene epoxidase;
DE            Short=SE;
GN   Name=SQLE; Synonyms=ERG1;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004506; F:squalene monooxygenase activity; NAS:UniProtKB.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:Ensembl.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016126; P:sterol biosynthetic process; NAS:UniProtKB.
//
ID   ERG24_HUMAN             Reviewed;         418 AA.
AC   O76062; A8K4H0; O95982; Q8IY06; Q96E64; Q96GZ1;
DE   RecName: Full=Delta(14)-sterol reductase;
DE            Short=Delta-14-SR;
DE            EC=1.3.1.70;
DE   AltName: Full=Another new gene 1 protein;
DE   AltName: Full=C-14 sterol reductase;
DE   AltName: Full=Putative sterol reductase SR-1;
DE   AltName: Full=Sterol C14-reductase;
DE   AltName: Full=Transmembrane 7 superfamily member 2;
GN   Name=TM7SF2; Synonyms=ANG1;
DR   GO; GO:0050613; F:delta14-sterol reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ERG28_HUMAN             Reviewed;         140 AA.
AC   Q9UKR5; Q9P093; Q9UPI2;
DE   RecName: Full=Probable ergosterol biosynthetic protein 28;
GN   Name=C14orf1; ORFNames=AD-011, HSPC288, x0006;
DR   GO; GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
//
ID   ERG7_HUMAN              Reviewed;         732 AA.
AC   P48449; B4DJZ9; D3DSN0; E9PEI9; G5E9Q9; Q8IYL6; Q9UEZ1;
DE   RecName: Full=Lanosterol synthase;
DE            EC=5.4.99.7;
DE   AltName: Full=2,3-epoxysqualene--lanosterol cyclase;
DE   AltName: Full=Oxidosqualene--lanosterol cyclase;
DE            Short=OSC;
DE            Short=hOSC;
GN   Name=LSS; Synonyms=OSC;
DR   GuidetoPHARMACOLOGY; 2434; -.
DR   GO; GO:0000250; F:lanosterol synthase activity; TAS:ProtInc.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
//
ID   ERGI1_HUMAN             Reviewed;         290 AA.
AC   Q969X5; Q9H0L0; Q9H2J2; Q9ULN9;
DE   RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1;
DE   AltName: Full=ER-Golgi intermediate compartment 32 kDa protein;
DE            Short=ERGIC-32;
GN   Name=ERGIC1; Synonyms=ERGIC32, KIAA1181; ORFNames=HT034;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:HGNC.
//
ID   ERGI2_HUMAN             Reviewed;         377 AA.
AC   Q96RQ1; A6NHH6; Q53GY2; Q8N2Q9; Q9BVV9; Q9NZA3;
DE   RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 2;
GN   Name=ERGIC2; Synonyms=ERV41, PTX1; ORFNames=CDA14;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ERGI3_HUMAN             Reviewed;         383 AA.
AC   Q9Y282; Q5JWS3; Q6ZWP7; Q9H276; Q9P1L3;
DE   RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-84;
GN   Name=ERGIC3; Synonyms=C20orf47, ERV46, SDBCAG84;
GN   ORFNames=CGI-54, PRO0989;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ERG_HUMAN               Reviewed;         486 AA.
AC   P11308; B4DTW5; B4E0T4; Q16113; Q6XXX4; Q6XXX5; Q8IXK9;
DE   RecName: Full=Transcriptional regulator ERG;
DE   AltName: Full=Transforming protein ERG;
GN   Name=ERG;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ERH_HUMAN               Reviewed;         104 AA.
AC   P84090; B2R5H2; P70659; Q14259;
DE   RecName: Full=Enhancer of rudimentary homolog;
GN   Name=ERH;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006213; P:pyrimidine nucleoside metabolic process; TAS:ProtInc.
//
ID   ERI1_HUMAN              Reviewed;         349 AA.
AC   Q8IV48; A8K4U7; Q9NSX3;
DE   RecName: Full=3'-5' exoribonuclease 1;
DE            EC=3.1.-.-;
DE   AltName: Full=3'-5' exonuclease ERI1;
DE   AltName: Full=Eri-1 homolog;
DE   AltName: Full=Histone mRNA 3'-end-specific exoribonuclease;
DE   AltName: Full=Histone mRNA 3'-exonuclease 1;
DE   AltName: Full=Protein 3'hExo;
DE            Short=HEXO;
GN   Name=ERI1; Synonyms=3'EXO, THEX1;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0071207; F:histone pre-mRNA stem-loop binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0031125; P:rRNA 3'-end processing; ISS:UniProtKB.
//
ID   ERI3_HUMAN              Reviewed;         337 AA.
AC   O43414; B1AK98; Q5T2T7; Q5T2T9; Q5TG35; Q9BQA0; Q9UEB4;
DE   RecName: Full=ERI1 exoribonuclease 3;
DE            EC=3.1.-.-;
DE   AltName: Full=Prion interactor 1;
DE   AltName: Full=Prion protein-interacting protein;
GN   Name=ERI3; Synonyms=PINT1, PRNPIP, PRNPIP1;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   ERI2_HUMAN              Reviewed;         691 AA.
AC   A8K979; Q6ZSJ2; Q96FR9; Q9P224; Q9Y6V3;
DE   RecName: Full=ERI1 exoribonuclease 2;
DE            EC=3.1.-.-;
DE   AltName: Full=Exonuclease domain-containing protein 1;
GN   Name=ERI2; Synonyms=EXOD1, KIAA1504;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ERI6B_HUMAN             Reviewed;         696 AA.
AC   Q5W0A0; Q96MB5;
DE   RecName: Full=Glutamate-rich protein 6B;
DE   AltName: Full=Protein FAM194B;
GN   Name=ERICH6B; Synonyms=FAM194B;
//
ID   ERIC1_HUMAN             Reviewed;         443 AA.
AC   Q86X53; A8K2J9; Q9P063;
DE   RecName: Full=Glutamate-rich protein 1;
GN   Name=ERICH1; ORFNames=HSPC319;
//
ID   ERIC3_HUMAN             Reviewed;        1530 AA.
AC   Q5RHP9; Q68DL8; Q6GMR8; Q6ZSF9; Q8ND41;
DE   RecName: Full=Glutamate-rich protein 3;
GN   Name=ERICH3; Synonyms=C1orf173;
//
ID   ERIC2_HUMAN             Reviewed;         156 AA.
AC   A1L162; A7E2T7;
DE   RecName: Full=Glutamate-rich protein 2;
GN   Name=ERICH2;
//
ID   ERIC4_HUMAN             Reviewed;         130 AA.
AC   A6NGS2;
DE   RecName: Full=Glutamate-rich protein 4;
GN   Name=ERICH4; Synonyms=C19orf69;
//
ID   ERIP6_HUMAN             Reviewed;         663 AA.
AC   Q7L0X2; Q8N9Y8; Q8NCQ6; Q8NCZ6;
DE   RecName: Full=Glutamate-rich protein 6;
DE   AltName: Full=Protein FAM194A;
GN   Name=ERICH6; Synonyms=C3orf44, FAM194A;
//
ID   ERIC5_HUMAN             Reviewed;         374 AA.
AC   Q6P6B1; G3V1K4; Q8N1L8;
DE   RecName: Full=Glutamate-rich protein 5;
GN   Name=ERICH5; Synonyms=C8orf47;
//
ID   ERIT1_HUMAN             Reviewed;         136 AA.
AC   O76042; Q6NT35;
DE   RecName: Full=Putative uncharacterized protein encoded by ERC2-IT1;
DE   AltName: Full=ERC2 intronic transcript protein 1;
DE   AltName: Full=PO42;
GN   Name=ERC2-IT1; Synonyms=C1orf1, C3orf51;
//
ID   ERLEC_HUMAN             Reviewed;         483 AA.
AC   Q96DZ1; B2RDB4; B5MC72; O95901; Q6UWN7; Q9NUY7; Q9UQL4;
DE   RecName: Full=Endoplasmic reticulum lectin 1;
DE   AltName: Full=ER lectin;
DE            Short=Erlectin;
DE   AltName: Full=XTP3-transactivated gene B protein;
DE   Flags: Precursor;
GN   Name=ERLEC1; Synonyms=C2orf30, XTP3TPB; ORFNames=UNQ1878/PRO4321;
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   ERLN1_HUMAN             Reviewed;         346 AA.
AC   O75477; B0QZ42; Q53HV0;
DE   RecName: Full=Erlin-1;
DE   AltName: Full=Endoplasmic reticulum lipid raft-associated protein 1;
DE   AltName: Full=Protein KE04;
DE   AltName: Full=Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1;
DE            Short=SPFH domain-containing protein 1;
GN   Name=ERLIN1; Synonyms=C10orf69, KE04, KEO4, SPFH1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   ERLN2_HUMAN             Reviewed;         339 AA.
AC   O94905; A0JLQ1; A8K5S9; B4DM38; D3DSW0; Q6NW21; Q86VS6; Q86W49;
DE   RecName: Full=Erlin-2;
DE   AltName: Full=Endoplasmic reticulum lipid raft-associated protein 2;
DE   AltName: Full=Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2;
DE            Short=SPFH domain-containing protein 2;
GN   Name=ERLIN2; Synonyms=C8orf2, SPFH2; ORFNames=UNQ2441/PRO5003/PRO9924;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   ERMAP_HUMAN             Reviewed;         475 AA.
AC   Q96PL5; D3DPW8; Q5VV53; Q6DUE0; Q7Z3X0; Q8NCV8; Q8NCW2; Q8NCW3;
AC   Q96PL6;
DE   RecName: Full=Erythroid membrane-associated protein;
DE            Short=hERMAP;
DE   AltName: Full=Radin blood group antigen;
DE   AltName: Full=Scianna blood group antigen;
DE   Flags: Precursor;
GN   Name=ERMAP; Synonyms=RD, SC;
//
ID   ERMIN_HUMAN             Reviewed;         284 AA.
AC   Q8TAM6; B4DKA6; Q9ULN1;
DE   RecName: Full=Ermin;
DE   AltName: Full=Juxtanodin;
DE            Short=JN;
GN   Name=ERMN; Synonyms=KIAA1189;
DR   GO; GO:0007015; P:actin filament organization; IDA:UniProt.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; IEA:Ensembl.
DR   GO; GO:0031344; P:regulation of cell projection organization; IDA:UniProt.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProt.
//
ID   ERMP1_HUMAN             Reviewed;         904 AA.
AC   Q7Z2K6; B2RNA4; Q8N5T5; Q9H5M1;
DE   RecName: Full=Endoplasmic reticulum metallopeptidase 1;
DE            EC=3.4.-.-;
DE   AltName: Full=Felix-ina;
GN   Name=ERMP1; Synonyms=FXNA, KIAA1815;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
//
ID   ERN1_HUMAN              Reviewed;         977 AA.
AC   O75460; A1L457; A8K8N8; A8MXS7; Q59EE2;
DE   RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE1;
DE   AltName: Full=Endoplasmic reticulum-to-nucleus signaling 1;
DE   AltName: Full=Inositol-requiring protein 1;
DE            Short=hIRE1p;
DE   AltName: Full=Ire1-alpha;
DE            Short=IRE1a;
DE   Includes:
DE     RecName: Full=Serine/threonine-protein kinase;
DE              EC=2.7.11.1;
DE   Includes:
DE     RecName: Full=Endoribonuclease;
DE              EC=3.1.26.-;
DE   Flags: Precursor;
GN   Name=ERN1; Synonyms=IRE1;
DR   GuidetoPHARMACOLOGY; 2020; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004521; F:endoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0070055; P:HAC1-type intron splice site recognition and cleavage; IDA:WormBase.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ERN2_HUMAN              Reviewed;         926 AA.
AC   Q76MJ5; Q6ZNC0;
DE   RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2;
DE   AltName: Full=Endoplasmic reticulum-to-nucleus signaling 2;
DE   AltName: Full=Inositol-requiring protein 2;
DE            Short=hIRE2p;
DE   AltName: Full=Ire1-beta;
DE            Short=IRE1b;
DE   Includes:
DE     RecName: Full=Serine/threonine-protein kinase;
DE              EC=2.7.11.1;
DE   Includes:
DE     RecName: Full=Endoribonuclease;
DE              EC=3.1.26.-;
DE   Flags: Precursor;
GN   Name=ERN2; Synonyms=IRE2;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004540; F:ribonuclease activity; IEA:InterPro.
DR   GO; GO:0030263; P:apoptotic chromosome condensation; IMP:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0016075; P:rRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ERO1A_HUMAN             Reviewed;         468 AA.
AC   Q96HE7; A8K9X4; A8MYW1; Q7LD45; Q9P1Q9; Q9UKV6;
DE   RecName: Full=ERO1-like protein alpha;
DE            Short=ERO1-L;
DE            Short=ERO1-L-alpha;
DE            EC=1.8.4.-;
DE   AltName: Full=Endoplasmic oxidoreductin-1-like protein;
DE   AltName: Full=Oxidoreductin-1-L-alpha;
DE   Flags: Precursor;
GN   Name=ERO1L; ORFNames=UNQ434/PRO865;
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IEA:InterPro.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IDA:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0009266; P:response to temperature stimulus; TAS:ProtInc.
//
ID   ERO1B_HUMAN             Reviewed;         467 AA.
AC   Q86YB8; Q5T1H4; Q8IZ11; Q9NR62;
DE   RecName: Full=ERO1-like protein beta;
DE            Short=ERO1-L-beta;
DE            EC=1.8.4.-;
DE   AltName: Full=Endoplasmic reticulum oxidoreductin-1-like protein B;
DE   AltName: Full=Oxidoreductin-1-L-beta;
DE   Flags: Precursor;
GN   Name=ERO1LB;
DR   GO; GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.
DR   GO; GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
//
ID   ERP29_HUMAN             Reviewed;         261 AA.
AC   P30040; C9J183; Q3MJC3; Q6FHT4;
DE   RecName: Full=Endoplasmic reticulum resident protein 29;
DE            Short=ERp29;
DE   AltName: Full=Endoplasmic reticulum resident protein 28;
DE            Short=ERp28;
DE   AltName: Full=Endoplasmic reticulum resident protein 31;
DE            Short=ERp31;
DE   Flags: Precursor;
GN   Name=ERP29; Synonyms=C12orf8, ERP28;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
//
ID   ERP27_HUMAN             Reviewed;         273 AA.
AC   Q96DN0;
DE   RecName: Full=Endoplasmic reticulum resident protein 27;
DE            Short=ER protein 27;
DE            Short=ERp27;
DE   Flags: Precursor;
GN   Name=ERP27; Synonyms=C12orf46; ORFNames=UNQ781/PRO1575;
//
ID   ERP44_HUMAN             Reviewed;         406 AA.
AC   Q9BS26; O60319; Q4VXC1; Q5VWZ7; Q6UW14; Q8WX67;
DE   RecName: Full=Endoplasmic reticulum resident protein 44;
DE            Short=ER protein 44;
DE            Short=ERp44;
DE   AltName: Full=Thioredoxin domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=ERP44; Synonyms=KIAA0573, TXNDC4; ORFNames=UNQ532/PRO1075;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; TAS:UniProtKB.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
//
ID   ERR1_HUMAN              Reviewed;         423 AA.
AC   P11474; Q14514;
DE   RecName: Full=Steroid hormone receptor ERR1;
DE   AltName: Full=Estrogen receptor-like 1;
DE   AltName: Full=Estrogen-related receptor alpha;
DE            Short=ERR-alpha;
DE   AltName: Full=Nuclear receptor subfamily 3 group B member 1;
GN   Name=ESRRA; Synonyms=ERR1, ESRL1, NR3B1;
DR   GuidetoPHARMACOLOGY; 622; -.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0005496; F:steroid binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   ERR2_HUMAN              Reviewed;         508 AA.
AC   O95718; A2VDJ2; B6ZGU4; Q5F0P7; Q5F0P8; Q9HCB4;
DE   RecName: Full=Steroid hormone receptor ERR2;
DE   AltName: Full=ERR beta-2;
DE   AltName: Full=Estrogen receptor-like 2;
DE   AltName: Full=Estrogen-related receptor beta;
DE            Short=ERR-beta;
DE   AltName: Full=Nuclear receptor subfamily 3 group B member 2;
GN   Name=ESRRB; Synonyms=ERRB2, ESRL2, NR3B2;
DR   GuidetoPHARMACOLOGY; 623; -.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0005496; F:steroid binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0001834; P:trophectodermal cell proliferation; IEA:Ensembl.
DR   GO; GO:0001831; P:trophectodermal cellular morphogenesis; IEA:Ensembl.
//
ID   ERR3_HUMAN              Reviewed;         458 AA.
AC   P62508; A8K4I0; A8K6I2; B3KY84; E9PGB7; F8W8J3; O75454; O96021;
AC   Q68DA0; Q6P274; Q6PK28; Q6TS38; Q9R1F3; Q9UNJ4;
DE   RecName: Full=Estrogen-related receptor gamma;
DE   AltName: Full=ERR gamma-2;
DE   AltName: Full=Estrogen receptor-related protein 3;
DE   AltName: Full=Nuclear receptor subfamily 3 group B member 3;
GN   Name=ESRRG; Synonyms=ERR3, ERRG2, KIAA0832, NR3B3;
DR   GuidetoPHARMACOLOGY; 624; -.
DR   GO; GO:0050682; F:AF-2 domain binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003708; F:retinoic acid receptor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0005496; F:steroid binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   ERRFI_HUMAN             Reviewed;         462 AA.
AC   Q9UJM3; B2RDX9; Q9NTG9; Q9UD05;
DE   RecName: Full=ERBB receptor feedback inhibitor 1;
DE   AltName: Full=Mitogen-inducible gene 6 protein;
DE            Short=MIG-6;
GN   Name=ERRFI1; Synonyms=MIG6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0048286; P:lung alveolus development; ISS:UniProtKB.
DR   GO; GO:0060428; P:lung epithelium development; ISS:UniProtKB.
DR   GO; GO:0060426; P:lung vasculature development; ISS:UniProtKB.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0043589; P:skin morphogenesis; ISS:UniProtKB.
//
ID   ERVV2_HUMAN             Reviewed;         535 AA.
AC   B6SEH9;
DE   RecName: Full=HERV-V_19q13.41 provirus ancestral Env polyprotein 2;
DE   AltName: Full=Endogenous retrovirus group V, member 2;
DE   Flags: Precursor;
GN   Name=ERVV-2; Synonyms=ENVV2;
//
ID   ERVV1_HUMAN             Reviewed;         477 AA.
AC   B6SEH8;
DE   RecName: Full=HERV-V_19q13.41 provirus ancestral Env polyprotein 1;
DE   AltName: Full=Endogenous retrovirus group V, member 1;
DE   Flags: Precursor;
GN   Name=ERVV-1; Synonyms=ENVV1;
//
ID   ES1_HUMAN               Reviewed;         268 AA.
AC   P30042; A6NFJ6; A6NJY7; O00650; O00660; O15011; O15012; P55346;
AC   P78474; Q92505; Q92507;
DE   RecName: Full=ES1 protein homolog, mitochondrial;
DE   AltName: Full=Protein GT335;
DE   AltName: Full=Protein KNP-I;
DE   Flags: Precursor;
GN   Name=C21orf33; Synonyms=HES1, KNPI;
//
ID   ES8L1_HUMAN             Reviewed;         723 AA.
AC   Q8TE68; Q71RE2; Q8NC10; Q96BB7; Q9BSQ2; Q9GZQ2; Q9NXH0;
DE   RecName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 1;
DE            Short=EPS8-like protein 1;
DE   AltName: Full=Epidermal growth factor receptor pathway substrate 8-related protein 1;
DE            Short=EPS8-related protein 1;
GN   Name=EPS8L1; Synonyms=DRC3, EPS8R1; ORFNames=PP10566;
DR   GO; GO:0003779; F:actin binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042608; F:T cell receptor binding; IPI:UniProt.
DR   GO; GO:1900029; P:positive regulation of ruffle assembly; IGI:UniProt.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; IDA:UniProt.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProt.
//
ID   ES8L2_HUMAN             Reviewed;         715 AA.
AC   Q9H6S3; B3KSX1; B7ZKL3; Q53GM8; Q8WYW7; Q96K06; Q9H6K9;
DE   RecName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 2;
DE            Short=EPS8-like protein 2;
DE   AltName: Full=Epidermal growth factor receptor pathway substrate 8-related protein 2;
DE            Short=EPS8-related protein 2;
GN   Name=EPS8L2; Synonyms=EPS8R2; ORFNames=PP13181;
DR   GO; GO:0003779; F:actin binding; IDA:UniProt.
DR   GO; GO:1900029; P:positive regulation of ruffle assembly; IGI:UniProt.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; IDA:UniProt.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProt.
//
ID   ES8L3_HUMAN             Reviewed;         593 AA.
AC   Q8TE67; A8K833; Q5T8Q6; Q5T8Q7; Q5T8Q8; Q96E47; Q9H719;
DE   RecName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 3;
DE            Short=EPS8-like protein 3;
DE   AltName: Full=Epidermal growth factor receptor pathway substrate 8-related protein 3;
DE            Short=EPS8-related protein 3;
GN   Name=EPS8L3; Synonyms=EPS8R3;
//
ID   ESAM_HUMAN              Reviewed;         390 AA.
AC   Q96AP7; Q96T50;
DE   RecName: Full=Endothelial cell-selective adhesion molecule;
DE   Flags: Precursor;
GN   Name=ESAM; ORFNames=UNQ220/PRO246;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
//
ID   ESCO1_HUMAN             Reviewed;         840 AA.
AC   Q5FWF5; B0YJ11; B0YJ12; Q69YG4; Q69YS3; Q6IMD7; Q8N3Z5; Q8NBG2;
AC   Q96PX7;
DE   RecName: Full=N-acetyltransferase ESCO1;
DE            EC=2.3.1.-;
DE   AltName: Full=CTF7 homolog 1;
DE   AltName: Full=Establishment factor-like protein 1;
DE            Short=EFO1p;
DE            Short=hEFO1;
DE   AltName: Full=Establishment of cohesion 1 homolog 1;
DE            Short=ECO1 homolog 1;
DE            Short=ESO1 homolog 1;
GN   Name=ESCO1; Synonyms=EFO1, KIAA1911;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034421; P:post-translational protein acetylation; IMP:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; IMP:UniProtKB.
//
ID   ESCO2_HUMAN             Reviewed;         601 AA.
AC   Q56NI9; B3KW59;
DE   RecName: Full=N-acetyltransferase ESCO2;
DE            EC=2.3.1.-;
DE   AltName: Full=Establishment of cohesion 1 homolog 2;
DE            Short=ECO1 homolog 2;
GN   Name=ESCO2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034421; P:post-translational protein acetylation; IMP:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; IMP:UniProtKB.
//
ID   ESF1_HUMAN              Reviewed;         851 AA.
AC   Q9H501; Q86X92; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6;
DE   RecName: Full=ESF1 homolog;
DE   AltName: Full=ABT1-associated protein;
GN   Name=ESF1; Synonyms=ABTAP, C20orf6; ORFNames=HDCMC28P;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ESIP1_HUMAN             Reviewed;         318 AA.
AC   Q96J88; Q8IVC7; Q8NDQ7;
DE   RecName: Full=Epithelial-stromal interaction protein 1;
GN   Name=EPSTI1;
//
ID   ESM1_HUMAN              Reviewed;         184 AA.
AC   Q9NQ30; B2R4G3; Q15330; Q3V4E3; Q96ES3;
DE   RecName: Full=Endothelial cell-specific molecule 1;
DE            Short=ESM-1;
DE   Flags: Precursor;
GN   Name=ESM1;
DR   GO; GO:0005171; F:hepatocyte growth factor receptor binding; IPI:UniProt.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProt.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProt.
DR   GO; GO:1902204; P:positive regulation of hepatocyte growth factor receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0002040; P:sprouting angiogenesis; IMP:UniProt.
//
ID   ESPB1_HUMAN             Reviewed;         223 AA.
AC   Q96BH3; Q96RT0; Q9H4C8;
DE   RecName: Full=Epididymal sperm-binding protein 1;
DE   AltName: Full=Epididymal secretory protein 12;
DE            Short=hE12;
DE   Flags: Precursor;
GN   Name=ELSPBP1; Synonyms=E12;
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
//
ID   ESPL1_HUMAN             Reviewed;        2120 AA.
AC   Q14674;
DE   RecName: Full=Separin;
DE            EC=3.4.22.49;
DE   AltName: Full=Caspase-like protein ESPL1;
DE   AltName: Full=Extra spindle poles-like 1 protein;
DE   AltName: Full=Separase;
GN   Name=ESPL1; Synonyms=ESP1, KIAA0165;
DR   GO; GO:0003824; F:catalytic activity; NAS:UniProtKB.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; NAS:UniProtKB.
DR   GO; GO:0040001; P:establishment of mitotic spindle localization; NAS:UniProtKB.
DR   GO; GO:0045143; P:homologous chromosome segregation; IEA:Ensembl.
DR   GO; GO:0000212; P:meiotic spindle organization; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0045875; P:negative regulation of sister chromatid cohesion; NAS:UniProtKB.
DR   GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; NAS:UniProtKB.
//
ID   ESPNL_HUMAN             Reviewed;        1005 AA.
AC   Q6ZVH7; Q66K27; Q6ZVG1; Q8IVU2;
DE   RecName: Full=Espin-like protein;
GN   Name=ESPNL;
//
ID   ESPN_HUMAN              Reviewed;         854 AA.
AC   B1AK53; Q6XYB2; Q9H0A2; Q9Y329;
DE   RecName: Full=Espin;
DE   AltName: Full=Autosomal recessive deafness type 36 protein;
DE   AltName: Full=Ectoplasmic specialization protein;
GN   Name=ESPN; Synonyms=DFNB36; ORFNames=LP2654;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0051494; P:negative regulation of cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0030046; P:parallel actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
//
ID   ESR1_HUMAN              Reviewed;         595 AA.
AC   P03372; Q13511; Q14276; Q5T5H7; Q6MZQ9; Q9NU51; Q9UDZ7; Q9UIS7;
DE   RecName: Full=Estrogen receptor;
DE            Short=ER;
DE   AltName: Full=ER-alpha;
DE   AltName: Full=Estradiol receptor;
DE   AltName: Full=Nuclear receptor subfamily 3 group A member 1;
GN   Name=ESR1; Synonyms=ESR, NR3A1;
DR   GuidetoPHARMACOLOGY; 620; -.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030284; F:estrogen receptor activity; NAS:UniProtKB.
DR   GO; GO:0034056; F:estrogen response element binding; IDA:UniProtKB.
DR   GO; GO:0038052; F:estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IGI:MGI.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0030235; F:nitric-oxide synthase regulator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:BHF-UCL.
DR   GO; GO:0005496; F:steroid binding; ISS:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0001547; P:antral ovarian follicle growth; IEA:Ensembl.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; ISS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0002064; P:epithelial cell development; IEA:Ensembl.
DR   GO; GO:0060750; P:epithelial cell proliferation involved in mammary gland duct elongation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0060745; P:mammary gland branching involved in pregnancy; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; ISS:UniProtKB.
DR   GO; GO:0048386; P:positive regulation of retinoic acid receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR   GO; GO:0060523; P:prostate epithelial cord elongation; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0060065; P:uterus development; IEA:Ensembl.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   ESR2_HUMAN              Reviewed;         530 AA.
AC   Q92731; A8K8K5; O60608; O60685; O60702; O60703; O75583; O75584;
AC   Q0MWT5; Q0MWT6; Q86Z31; Q9UEV6; Q9UHD3; Q9UQK9;
DE   RecName: Full=Estrogen receptor beta;
DE            Short=ER-beta;
DE   AltName: Full=Nuclear receptor subfamily 3 group A member 2;
GN   Name=ESR2; Synonyms=ESTRB, NR3A2;
DR   GuidetoPHARMACOLOGY; 621; -.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030284; F:estrogen receptor activity; TAS:UniProtKB.
DR   GO; GO:0034056; F:estrogen response element binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048019; F:receptor antagonist activity; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005496; F:steroid binding; ISS:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0060743; P:epithelial cell maturation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; NAS:GOC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008628; P:hormone-mediated apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0060065; P:uterus development; IEA:Ensembl.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   ESRP1_HUMAN             Reviewed;         681 AA.
AC   Q6NXG1; A6NHA8; A8MPX1; E9PB47; Q2M2B0; Q499G3; Q6PJ86; Q9NXL8;
DE   RecName: Full=Epithelial splicing regulatory protein 1;
DE   AltName: Full=RNA-binding motif protein 35A;
DE   AltName: Full=RNA-binding protein 35A;
GN   Name=ESRP1; Synonyms=RBM35A;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   ESRP2_HUMAN             Reviewed;         727 AA.
AC   Q9H6T0; Q8N6H8; Q8WZ15; Q9H6I4;
DE   RecName: Full=Epithelial splicing regulatory protein 2;
DE   AltName: Full=RNA-binding motif protein 35B;
DE   AltName: Full=RNA-binding protein 35B;
GN   Name=ESRP2; Synonyms=RBM35B; ORFNames=PP7059;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   EST1A_HUMAN             Reviewed;        1419 AA.
AC   Q86US8; B7Z874; O94837; Q86VH6; Q9UF60;
DE   RecName: Full=Telomerase-binding protein EST1A;
DE            EC=3.1.-.-;
DE   AltName: Full=EST1-like protein A;
DE   AltName: Full=Ever shorter telomeres 1A;
DE   AltName: Full=Smg-6 homolog;
DE   AltName: Full=Telomerase subunit EST1A;
DE   AltName: Full=hSmg5/7a;
GN   Name=SMG6; Synonyms=C17orf31, EST1A, KIAA0732;
DR   GO; GO:0004521; F:endoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:HGNC.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0035303; P:regulation of dephosphorylation; TAS:HGNC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0000723; P:telomere maintenance; IMP:HGNC.
//
ID   EST1_HUMAN              Reviewed;         567 AA.
AC   P23141; A6NIM1; A8K3K8; A8K844; E9PAU8; P82127; Q00015; Q13657;
AC   Q14062; Q16737; Q16788; Q549X7; Q549X8; Q86UK2; Q96EE8; Q9UC52;
AC   Q9UDG8; Q9UK77; Q9ULY2;
DE   RecName: Full=Liver carboxylesterase 1;
DE   AltName: Full=Acyl-coenzyme A:cholesterol acyltransferase;
DE            Short=ACAT;
DE   AltName: Full=Brain carboxylesterase hBr1;
DE   AltName: Full=Carboxylesterase 1;
DE            Short=CE-1;
DE            Short=hCE-1;
DE            EC=3.1.1.1;
DE   AltName: Full=Cocaine carboxylesterase;
DE   AltName: Full=Egasyn;
DE   AltName: Full=HMSE;
DE   AltName: Full=Methylumbelliferyl-acetate deacetylase 1;
DE            EC=3.1.1.56;
DE   AltName: Full=Monocyte/macrophage serine esterase;
DE   AltName: Full=Retinyl ester hydrolase;
DE            Short=REH;
DE   AltName: Full=Serine esterase 1;
DE   AltName: Full=Triacylglycerol hydrolase;
DE            Short=TGH;
DE   Flags: Precursor;
GN   Name=CES1; Synonyms=CES2, SES1;
DR   GuidetoPHARMACOLOGY; 2592; -.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; TAS:ProtInc.
DR   GO; GO:0047374; F:methylumbelliferyl-acetate deacetylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProt.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0009636; P:response to toxic substance; TAS:ProtInc.
//
ID   EST2_HUMAN              Reviewed;         559 AA.
AC   O00748; A8K367; Q16859; Q5MAB8; Q7Z366; Q8IUP4; Q8TCP8;
DE   RecName: Full=Cocaine esterase;
DE            EC=3.1.1.84;
DE   AltName: Full=Carboxylesterase 2;
DE            Short=CE-2;
DE            Short=hCE-2;
DE            EC=3.1.1.1;
DE   AltName: Full=Methylumbelliferyl-acetate deacetylase 2;
DE            EC=3.1.1.56;
DE   Flags: Precursor;
GN   Name=CES2; Synonyms=ICE;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; TAS:ProtInc.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0047374; F:methylumbelliferyl-acetate deacetylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009056; P:catabolic process; TAS:ProtInc.
//
ID   EST3_HUMAN              Reviewed;         571 AA.
AC   Q6UWW8; B2Z3W9; F5H242; Q7Z6J1; Q9H6X7;
DE   RecName: Full=Carboxylesterase 3;
DE            EC=3.1.1.1;
DE   AltName: Full=Liver carboxylesterase 31 homolog;
DE   Flags: Precursor;
GN   Name=CES3; ORFNames=UNQ869/PRO1887;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-EC.
//
ID   EST4A_HUMAN             Reviewed;         561 AA.
AC   Q5XG92; A8KAJ6; B7Z349; B7Z3L2; B7Z6R3; Q6UX55; Q8N9F4;
DE   RecName: Full=Carboxylesterase 4A;
DE            EC=3.1.1.-;
DE   Flags: Precursor;
GN   Name=CES4A; Synonyms=CES8; ORFNames=UNQ440/PRO873;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   EST5A_HUMAN             Reviewed;         575 AA.
AC   Q6NT32; B7Z252; B7ZLB6; Q8NBC8; Q96DN9;
DE   RecName: Full=Carboxylesterase 5A;
DE            EC=3.1.1.1;
DE   AltName: Full=Carboxylesterase-like urinary excreted protein homolog;
DE            Short=Cauxin;
DE   Flags: Precursor;
GN   Name=CES5A; Synonyms=CES7;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-EC.
//
ID   ESTD_HUMAN              Reviewed;         282 AA.
AC   P10768; Q5TBU8; Q5TBV0; Q5TBV2; Q9BVJ2;
DE   RecName: Full=S-formylglutathione hydrolase;
DE            Short=FGH;
DE            EC=3.1.2.12;
DE   AltName: Full=Esterase D;
DE   AltName: Full=Methylumbelliferyl-acetate deacetylase;
DE            EC=3.1.1.56;
GN   Name=ESD;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; NAS:UniProtKB.
DR   GO; GO:0047374; F:methylumbelliferyl-acetate deacetylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018738; F:S-formylglutathione hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046294; P:formaldehyde catabolic process; IEA:InterPro.
//
ID   ESX1_HUMAN              Reviewed;         406 AA.
AC   Q8N693; B0QYU3; Q7Z6K7;
DE   RecName: Full=Homeobox protein ESX1;
DE   AltName: Full=Extraembryonic, spermatogenesis, homeobox 1;
DE   Contains:
DE     RecName: Full=Homeobox protein ESX1-N;
DE   Contains:
DE     RecName: Full=Homeobox protein ESX1-C;
GN   Name=ESX1; Synonyms=ESX1L, ESX1R;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0060713; P:labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ESYT1_HUMAN             Reviewed;        1104 AA.
AC   Q9BSJ8; A0FGR7; A8K2S2; O94848; Q6PJN4; Q9H6J1; Q9H6W2; Q9Y416;
DE   RecName: Full=Extended synaptotagmin-1;
DE            Short=E-Syt1;
DE   AltName: Full=Membrane-bound C2 domain-containing protein;
GN   Name=ESYT1; Synonyms=FAM62A, KIAA0747, MBC2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ESYT2_HUMAN             Reviewed;         921 AA.
AC   A0FGR8; A4D229; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47;
AC   Q9ULJ2;
DE   RecName: Full=Extended synaptotagmin-2;
DE            Short=E-Syt2;
DE   AltName: Full=Chr2Syt;
GN   Name=ESYT2; Synonyms=FAM62B, KIAA1228;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ESYT3_HUMAN             Reviewed;         886 AA.
AC   A0FGR9; A8K0G5; Q6ZV21; Q8NDZ5; Q9BQR9;
DE   RecName: Full=Extended synaptotagmin-3;
DE            Short=E-Syt3;
DE   AltName: Full=Chr3Syt;
GN   Name=ESYT3; Synonyms=FAM62C;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ETAA1_HUMAN             Reviewed;         926 AA.
AC   Q9NY74; Q05BT7; Q53SC4;
DE   RecName: Full=Ewing's tumor-associated antigen 1;
DE   AltName: Full=Ewing's tumor-associated antigen 16;
GN   Name=ETAA1; Synonyms=ETAA16;
//
ID   ETBR2_HUMAN             Reviewed;         481 AA.
AC   O60883; B2R7M9; Q5SXP7; Q86VP7;
DE   RecName: Full=Prosaposin receptor GPR37L1;
DE   AltName: Full=Endothelin B receptor-like protein 2;
DE            Short=ETBR-LP-2;
DE   AltName: Full=G-protein coupled receptor 37-like 1;
DE   Flags: Precursor;
GN   Name=GPR37L1; Synonyms=ETBRLP2;
DR   GuidetoPHARMACOLOGY; 104; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ETFA_HUMAN              Reviewed;         333 AA.
AC   P13804; B4DT43; Q53XN3;
DE   RecName: Full=Electron transfer flavoprotein subunit alpha, mitochondrial;
DE            Short=Alpha-ETF;
DE   Flags: Precursor;
GN   Name=ETFA;
DR   GO; GO:0009055; F:electron carrier activity; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ETFB_HUMAN              Reviewed;         255 AA.
AC   P38117; B3KNY2; Q6IBH7; Q71RF6; Q9Y3S7;
DE   RecName: Full=Electron transfer flavoprotein subunit beta;
DE            Short=Beta-ETF;
GN   Name=ETFB; ORFNames=FP585;
DR   GO; GO:0009055; F:electron carrier activity; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ETFD_HUMAN              Reviewed;         617 AA.
AC   Q16134; Q7Z347;
DE   RecName: Full=Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial;
DE            Short=ETF-QO;
DE            Short=ETF-ubiquinone oxidoreductase;
DE            EC=1.5.5.1;
DE   AltName: Full=Electron-transferring-flavoprotein dehydrogenase;
DE            Short=ETF dehydrogenase;
DE   Flags: Precursor;
GN   Name=ETFDH;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; IDA:UniProtKB.
DR   GO; GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0043783; F:oxidoreductase activity, oxidizing metal ions with flavin as acceptor; ISS:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IDA:UniProtKB.
DR   GO; GO:0048039; F:ubiquinone binding; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022900; P:electron transport chain; IDA:UniProtKB.
DR   GO; GO:0033539; P:fatty acid beta-oxidation using acyl-CoA dehydrogenase; IMP:BHF-UCL.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ETHE1_HUMAN             Reviewed;         254 AA.
AC   O95571; Q96HR0; Q9H001;
DE   RecName: Full=Persulfide dioxygenase ETHE1, mitochondrial;
DE            EC=1.13.11.18;
DE   AltName: Full=Ethylmalonic encephalopathy protein 1;
DE   AltName: Full=Hepatoma subtracted clone one protein;
DE   AltName: Full=Sulfur dioxygenase ETHE1;
DE   Flags: Precursor;
GN   Name=ETHE1; Synonyms=HSCO;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0050313; F:sulfur dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0070813; P:hydrogen sulfide metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   ETS1_HUMAN              Reviewed;         441 AA.
AC   P14921; A9UL17; F5GYX9; Q14278; Q16080; Q6N087;
DE   RecName: Full=Protein C-ets-1;
DE   AltName: Full=p54;
GN   Name=ETS1; Synonyms=EWSR2;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0060055; P:angiogenesis involved in wound healing; IEA:Ensembl.
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0048870; P:cell motility; IMP:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0060206; P:estrous cycle phase; IEA:Ensembl.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0030578; P:PML body organization; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IMP:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045765; P:regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0010715; P:regulation of extracellular matrix disassembly; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IDA:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETS2_HUMAN              Reviewed;         469 AA.
AC   P15036; A6NM68; D3DSH6; Q53Y89;
DE   RecName: Full=Protein C-ets-2;
GN   Name=ETS2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETUD1_HUMAN             Reviewed;        1120 AA.
AC   Q7Z2Z2; A6NKY5; B7Z6I0; Q9H8Z6;
DE   RecName: Full=Elongation factor Tu GTP-binding domain-containing protein 1;
DE   AltName: Full=Elongation factor-like 1;
DE   AltName: Full=Protein FAM42A;
GN   Name=EFTUD1; Synonyms=EFL1, FAM42A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IMP:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0042256; P:mature ribosome assembly; IMP:UniProtKB.
//
ID   ETV1_HUMAN              Reviewed;         477 AA.
AC   P50549; A4D118; B2R768; B7Z2I4; B7Z618; B7Z9P2; C9JT37; E9PHB1;
AC   F5GXR2; O75849; Q4KMQ6; Q59GA7; Q6AI30; Q9UQ71; Q9Y636;
DE   RecName: Full=ETS translocation variant 1;
DE   AltName: Full=Ets-related protein 81;
GN   Name=ETV1; Synonyms=ER81;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0007638; P:mechanosensory behavior; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ETV2_HUMAN              Reviewed;         342 AA.
AC   O00321; B9EIN1; Q9UEA0;
DE   RecName: Full=ETS translocation variant 2;
DE   AltName: Full=Ets-related protein 71;
GN   Name=ETV2; Synonyms=ER71, ETSRP71;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0060803; P:BMP signaling pathway involved in mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:2000382; P:positive regulation of mesoderm development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   ETV3L_HUMAN             Reviewed;         361 AA.
AC   Q6ZN32;
DE   RecName: Full=ETS translocation variant 3-like protein;
GN   Name=ETV3L;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETV3_HUMAN              Reviewed;         512 AA.
AC   P41162; B4E3M7; Q8TAC8; Q9BX30;
DE   RecName: Full=ETS translocation variant 3;
DE   AltName: Full=ETS domain transcriptional repressor PE1;
DE            Short=PE-1;
DE   AltName: Full=Mitogenic Ets transcriptional suppressor;
GN   Name=ETV3; Synonyms=METS, PE1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETV4_HUMAN              Reviewed;         484 AA.
AC   P43268; A8K314; B7Z5J3; B7Z9J6; Q96AW9;
DE   RecName: Full=ETS translocation variant 4;
DE   AltName: Full=Adenovirus E1A enhancer-binding protein;
DE   AltName: Full=E1A-F;
DE   AltName: Full=Polyomavirus enhancer activator 3 homolog;
DE            Short=Protein PEA3;
GN   Name=ETV4; Synonyms=E1AF, PEA3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETV5_HUMAN              Reviewed;         510 AA.
AC   P41161; A6NH46; Q6IBN5;
DE   RecName: Full=ETS translocation variant 5;
DE   AltName: Full=Ets-related protein ERM;
GN   Name=ETV5; Synonyms=ERM;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0048133; P:male germ-line stem cell division; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0060252; P:positive regulation of glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0050807; P:regulation of synapse organization; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETV6_HUMAN              Reviewed;         452 AA.
AC   P41212; A3QVP6; A8K076; Q9UMF6; Q9UMF7; Q9UMG0;
DE   RecName: Full=Transcription factor ETV6;
DE   AltName: Full=ETS translocation variant 6;
DE   AltName: Full=ETS-related protein Tel1;
DE            Short=Tel;
GN   Name=ETV6; Synonyms=TEL, TEL1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ETV7_HUMAN              Reviewed;         341 AA.
AC   Q9Y603; B3KVC2; B4DVB6; B4E1G4; Q5R3L3; Q5R3L4; Q9NZ65; Q9NZ66;
AC   Q9NZ68; Q9NZR8; Q9UNJ7; Q9Y5K4; Q9Y604;
DE   RecName: Full=Transcription factor ETV7;
DE   AltName: Full=ETS translocation variant 7;
DE   AltName: Full=ETS-related protein Tel2;
DE   AltName: Full=Tel-related Ets factor;
DE   AltName: Full=Transcription factor Tel-2;
GN   Name=ETV7; Synonyms=TEL2, TELB, TREF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   EURL_HUMAN              Reviewed;         297 AA.
AC   Q9NYK6; B2RB30; Q96BK9; Q9H8C6;
DE   RecName: Full=Protein EURL homolog;
GN   Name=EURL; Synonyms=C21orf14, C21orf38, C21orf7, C21orf91, YG81;
//
ID   EVA1A_HUMAN             Reviewed;         152 AA.
AC   Q9H8M9; D6W5J3; Q9HC41;
DE   RecName: Full=Protein eva-1 homolog A;
DE   AltName: Full=Protein FAM176A;
DE   AltName: Full=Transmembrane protein 166;
GN   Name=EVA1A; Synonyms=FAM176A, TMEM166; ORFNames=SP24;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   EVA1B_HUMAN             Reviewed;         165 AA.
AC   Q9NVM1; D3DPS7;
DE   RecName: Full=Protein eva-1 homolog B;
DE   AltName: Full=Protein FAM176B;
GN   Name=EVA1B; Synonyms=C1orf78, FAM176B;
//
ID   EVA1C_HUMAN             Reviewed;         441 AA.
AC   P58658; Q8IXZ0;
DE   RecName: Full=Protein eva-1 homolog C;
DE   AltName: Full=Protein FAM176C;
DE   AltName: Full=SUE21;
DE   Flags: Precursor;
GN   Name=EVA1C; Synonyms=C21orf63, C21orf64, FAM176C;
GN   ORFNames=PRED34, UNQ2504/PRO5993;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   EVC_HUMAN               Reviewed;         992 AA.
AC   P57679;
DE   RecName: Full=Ellis-van Creveld syndrome protein;
DE   AltName: Full=DWF-1;
GN   Name=EVC;
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0003416; P:endochondral bone growth; ISS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:InterPro.
//
ID   EVG1_HUMAN              Reviewed;         217 AA.
AC   Q9BZE7; Q5JYU9; Q96M68;
DE   RecName: Full=UPF0193 protein EVG1;
GN   Name=C22orf23;
//
ID   EVI2A_HUMAN             Reviewed;         236 AA.
AC   P22794; B2R5X2; B4DHX8;
DE   RecName: Full=Protein EVI2A;
DE   AltName: Full=Ecotropic viral integration site 2A protein homolog;
DE            Short=EVI-2A;
DE   Flags: Precursor;
GN   Name=EVI2A; Synonyms=EVDA, EVI2;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   EVI2B_HUMAN             Reviewed;         448 AA.
AC   P34910;
DE   RecName: Full=Protein EVI2B;
DE   AltName: Full=Ecotropic viral integration site 2B protein homolog;
DE            Short=EVI-2B;
DE   AltName: CD_antigen=CD361;
DE   Flags: Precursor;
GN   Name=EVI2B; Synonyms=EVDB;
//
ID   EVI1_HUMAN              Reviewed;        1051 AA.
AC   Q03112; A1L4F3; A8KA00; B7Z8W7; B7ZLQ3; B7ZLQ4; C9JAK0; D3DNP7;
AC   Q16122; Q5HYI1; Q6MZS6; Q8NEI5; Q99917;
DE   RecName: Full=MDS1 and EVI1 complex locus protein EVI1;
DE   AltName: Full=Ecotropic virus integration site 1 protein homolog;
DE            Short=EVI-1;
GN   Name=MECOM; Synonyms=EVI1;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001780; P:neutrophil homeostasis; IEA:Ensembl.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0072001; P:renal system development; IEA:Ensembl.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EVI5_HUMAN              Reviewed;         810 AA.
AC   O60447; A6NKX8; Q9H1Y9;
DE   RecName: Full=Ecotropic viral integration site 5 protein homolog;
DE            Short=EVI-5;
DE   AltName: Full=Neuroblastoma stage 4S gene protein;
GN   Name=EVI5; Synonyms=NB4S;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   EVI5L_HUMAN             Reviewed;         794 AA.
AC   Q96CN4; B9A6I9;
DE   RecName: Full=EVI5-like protein;
DE   AltName: Full=Ecotropic viral integration site 5-like protein;
GN   Name=EVI5L;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   EVL_HUMAN               Reviewed;         416 AA.
AC   Q9UI08; A8K105; O95884; Q7Z522; Q8TBV1; Q9UF25; Q9UIC2;
DE   RecName: Full=Ena/VASP-like protein;
DE   AltName: Full=Ena/vasodilator-stimulated phosphoprotein-like;
GN   Name=EVL; Synonyms=RNB6;
DR   GO; GO:0005522; F:profilin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; TAS:ProtInc.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IMP:UniProt.
DR   GO; GO:1900028; P:negative regulation of ruffle assembly; IMP:UniProt.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProt.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:InterPro.
//
ID   EVPLL_HUMAN             Reviewed;         301 AA.
AC   A8MZ36; B4DPD4;
DE   RecName: Full=Envoplakin-like protein;
GN   Name=EVPLL;
//
ID   EVPL_HUMAN              Reviewed;        2033 AA.
AC   Q92817; A0AUV5;
DE   RecName: Full=Envoplakin;
DE   AltName: Full=210 kDa cornified envelope precursor protein;
DE   AltName: Full=210 kDa paraneoplastic pemphigus antigen;
DE   AltName: Full=p210;
GN   Name=EVPL;
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
//
ID   EVX1_HUMAN              Reviewed;         407 AA.
AC   P49640; A4D199;
DE   RecName: Full=Homeobox even-skipped homolog protein 1;
DE   AltName: Full=EVX-1;
GN   Name=EVX1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021913; P:regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; IEA:Ensembl.
//
ID   EVX2_HUMAN              Reviewed;         476 AA.
AC   Q03828;
DE   RecName: Full=Homeobox even-skipped homolog protein 2;
DE   AltName: Full=EVX-2;
GN   Name=EVX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
//
ID   EWS_HUMAN               Reviewed;         656 AA.
AC   Q01844; B0QYK1; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2;
DE   RecName: Full=RNA-binding protein EWS;
DE   AltName: Full=EWS oncogene;
DE   AltName: Full=Ewing sarcoma breakpoint region 1 protein;
GN   Name=EWSR1; Synonyms=EWS;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EX3L1_HUMAN             Reviewed;         746 AA.
AC   Q86VI1; A8K7I9; Q8NAD2; Q8TEN2;
DE   RecName: Full=Exocyst complex component 3-like protein;
DE   AltName: Full=Protein Jiangli;
GN   Name=EXOC3L1; Synonyms=EXOC3L;
DR   GO; GO:0006887; P:exocytosis; ISS:UniProtKB.
DR   GO; GO:0030072; P:peptide hormone secretion; ISS:UniProtKB.
//
ID   EX3L2_HUMAN             Reviewed;         409 AA.
AC   Q2M3D2; Q8N9W2; Q96GV2;
DE   RecName: Full=Exocyst complex component 3-like protein 2;
DE   AltName: Full=HBV X-transactivated gene 7 protein;
DE   AltName: Full=HBV XAg-transactivated protein 7;
GN   Name=EXOC3L2; Synonyms=XTP7;
DR   GO; GO:0006887; P:exocytosis; IEA:InterPro.
//
ID   EX3L4_HUMAN             Reviewed;         722 AA.
AC   Q17RC7; Q14CR2;
DE   RecName: Full=Exocyst complex component 3-like protein 4;
GN   Name=EXOC3L4; Synonyms=C14orf73;
DR   GO; GO:0006887; P:exocytosis; IEA:InterPro.
//
ID   EXC6B_HUMAN             Reviewed;         811 AA.
AC   Q9Y2D4; B8ZZY3;
DE   RecName: Full=Exocyst complex component 6B;
DE   AltName: Full=Exocyst complex component Sec15B;
DE   AltName: Full=SEC15-like protein 2;
GN   Name=EXOC6B; Synonyms=KIAA0919, SEC15B, SEC15L2;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   EXD1_HUMAN              Reviewed;         514 AA.
AC   Q8NHP7; A8K909; B7Z839; Q6ZW94;
DE   RecName: Full=Exonuclease 3'-5' domain-containing protein 1;
DE   AltName: Full=Exonuclease 3'-5' domain-like-containing protein 1;
GN   Name=EXD1; Synonyms=EXDL1;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   EXD2_HUMAN              Reviewed;         621 AA.
AC   Q9NVH0; B4DIH6; G5E947; Q6AWB6; Q8N3D3;
DE   RecName: Full=Exonuclease 3'-5' domain-containing protein 2;
DE   AltName: Full=Exonuclease 3'-5' domain-like-containing protein 2;
GN   Name=EXD2; Synonyms=C14orf114, EXDL2;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   EXO1_HUMAN              Reviewed;         846 AA.
AC   Q9UQ84; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0;
DE   RecName: Full=Exonuclease 1;
DE            Short=hExo1;
DE            EC=3.1.-.-;
DE   AltName: Full=Exonuclease I;
DE            Short=hExoI;
GN   Name=EXO1; Synonyms=EXOI, HEX1;
DR   GO; GO:0035312; F:5'-3' exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0008409; F:5'-3' exonuclease activity; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0051908; F:double-stranded DNA 5'-3' exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0004527; F:exonuclease activity; TAS:ProtInc.
DR   GO; GO:0048256; F:flap endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0045145; F:single-stranded DNA 5'-3' exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0043566; F:structure-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IGI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0006298; P:mismatch repair; IDA:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; ISS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Ensembl.
//
ID   EXO5_HUMAN              Reviewed;         373 AA.
AC   Q9H790; D3DPV4; Q5SWM7; Q5SWM8; Q5SWM9; Q5SWN0; Q5SWN1; Q8WTW9;
DE   RecName: Full=Exonuclease V;
DE            Short=Exo V;
DE            Short=hExo5;
DE            EC=3.1.-.-;
DE   AltName: Full=Defects in morphology protein 1 homolog;
GN   Name=EXO5; Synonyms=C1orf176, DEM1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0008310; F:single-stranded DNA 3'-5' exodeoxyribonuclease activity; TAS:UniProtKB.
DR   GO; GO:0045145; F:single-stranded DNA 5'-3' exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:GOC.
DR   GO; GO:0036297; P:interstrand cross-link repair; IMP:UniProtKB.
//
ID   EXOC1_HUMAN             Reviewed;         894 AA.
AC   Q9NV70; Q504V4; Q8WUE7; Q96T15; Q9NZE4;
DE   RecName: Full=Exocyst complex component 1;
DE   AltName: Full=Exocyst complex component Sec3;
GN   Name=EXOC1; Synonyms=SEC3, SEC3L1; ORFNames=BM-012;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   EXOC2_HUMAN             Reviewed;         924 AA.
AC   Q96KP1; B2RBE6; Q5JPC8; Q96AN6; Q9NUZ8; Q9UJM7;
DE   RecName: Full=Exocyst complex component 2;
DE   AltName: Full=Exocyst complex component Sec5;
GN   Name=EXOC2; Synonyms=SEC5, SEC5L1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   EXOC3_HUMAN             Reviewed;         756 AA.
AC   O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4;
DE   RecName: Full=Exocyst complex component 3;
DE   AltName: Full=Exocyst complex component Sec6;
GN   Name=EXOC3; Synonyms=SEC6, SEC6L1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   EXOC4_HUMAN             Reviewed;         974 AA.
AC   Q96A65; E9PED2; Q541U8; Q9C0G4; Q9H9K0; Q9P102;
DE   RecName: Full=Exocyst complex component 4;
DE   AltName: Full=Exocyst complex component Sec8;
GN   Name=EXOC4; Synonyms=KIAA1699, SEC8, SEC8L1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   EXOC5_HUMAN             Reviewed;         708 AA.
AC   O00471; B2R6C5;
DE   RecName: Full=Exocyst complex component 5;
DE   AltName: Full=Exocyst complex component Sec10;
DE            Short=hSec10;
GN   Name=EXOC5; Synonyms=SEC10, SEC10L1;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048278; P:vesicle docking; IEA:InterPro.
//
ID   EXOC6_HUMAN             Reviewed;         804 AA.
AC   Q8TAG9; E9PHI3; Q5VXH8; Q9NZ24;
DE   RecName: Full=Exocyst complex component 6;
DE   AltName: Full=Exocyst complex component Sec15A;
DE   AltName: Full=SEC15-like protein 1;
GN   Name=EXOC6; Synonyms=SEC15A, SEC15L, SEC15L1;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   EXOC7_HUMAN             Reviewed;         735 AA.
AC   Q9UPT5; B5MC69; B8XXP2; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3;
AC   Q9HA32;
DE   RecName: Full=Exocyst complex component 7;
DE   AltName: Full=Exocyst complex component Exo70;
GN   Name=EXOC7; Synonyms=EXO70, KIAA1067;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   EXOC8_HUMAN             Reviewed;         725 AA.
AC   Q8IYI6; B3KU33; Q5TE82;
DE   RecName: Full=Exocyst complex component 8;
DE   AltName: Full=Exocyst complex 84 kDa subunit;
GN   Name=EXOC8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   EXOG_HUMAN              Reviewed;         368 AA.
AC   Q9Y2C4; A8K242; B4DVG2; Q3SXM9; Q9Y2C8;
DE   RecName: Full=Nuclease EXOG, mitochondrial;
DE            EC=3.1.30.-;
DE   AltName: Full=Endonuclease G-like 1;
DE            Short=Endo G-like 1;
DE   Flags: Precursor;
GN   Name=EXOG; Synonyms=ENDOGL1, ENDOGL2, ENGL;
DR   GO; GO:0004519; F:endonuclease activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IBA:RefGenome.
//
ID   EXOS2_HUMAN             Reviewed;         293 AA.
AC   Q13868; A3KFL3; B4DKK6; Q9NUY4;
DE   RecName: Full=Exosome complex component RRP4;
DE   AltName: Full=Exosome component 2;
DE   AltName: Full=Ribosomal RNA-processing protein 4;
GN   Name=EXOSC2; Synonyms=RRP4;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; TAS:ProtInc.
DR   GO; GO:0008312; F:7S RNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; TAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
//
ID   EXOS1_HUMAN             Reviewed;         195 AA.
AC   Q9Y3B2; B2R9B3; Q5JTH3;
DE   RecName: Full=Exosome complex component CSL4;
DE   AltName: Full=Exosome component 1;
GN   Name=EXOSC1; Synonyms=CSL4; ORFNames=CGI-108;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   EXOS3_HUMAN             Reviewed;         275 AA.
AC   Q9NQT5; A8K0K6; Q5QP85; Q9Y3A8;
DE   RecName: Full=Exosome complex component RRP40;
DE   AltName: Full=Exosome component 3;
DE   AltName: Full=Ribosomal RNA-processing protein 40;
DE   AltName: Full=p10;
GN   Name=EXOSC3; Synonyms=RRP40; ORFNames=CGI-102;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0071034; P:CUT catabolic process; IMP:UniProtKB.
DR   GO; GO:0045006; P:DNA deamination; IDA:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0045830; P:positive regulation of isotype switching; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; NAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; IDA:UniProtKB.
//
ID   EXOS4_HUMAN             Reviewed;         245 AA.
AC   Q9NPD3;
DE   RecName: Full=Exosome complex component RRP41;
DE   AltName: Full=Exosome component 4;
DE   AltName: Full=Ribosomal RNA-processing protein 41;
DE   AltName: Full=p12A;
GN   Name=EXOSC4; Synonyms=RRP41, SKI6;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:MGI.
DR   GO; GO:0045006; P:DNA deamination; IDA:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0071028; P:nuclear mRNA surveillance; IMP:UniProtKB.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; NAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; NAS:UniProtKB.
//
ID   EXOS5_HUMAN             Reviewed;         235 AA.
AC   Q9NQT4; Q32Q81; Q8NG16; Q96I89;
DE   RecName: Full=Exosome complex component RRP46;
DE   AltName: Full=Chronic myelogenous leukemia tumor antigen 28;
DE   AltName: Full=Exosome component 5;
DE   AltName: Full=Ribosomal RNA-processing protein 46;
DE   AltName: Full=p12B;
GN   Name=EXOSC5; Synonyms=CML28, RRP46;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IMP:MGI.
DR   GO; GO:0045006; P:DNA deamination; IDA:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; NAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; NAS:UniProtKB.
//
ID   EXOS6_HUMAN             Reviewed;         272 AA.
AC   Q5RKV6;
DE   RecName: Full=Exosome complex component MTR3;
DE   AltName: Full=Exosome component 6;
DE   AltName: Full=mRNA transport regulator 3 homolog;
DE            Short=hMtr3;
DE   AltName: Full=p11;
GN   Name=EXOSC6; Synonyms=MTR3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0045006; P:DNA deamination; IDA:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   EXOS7_HUMAN             Reviewed;         291 AA.
AC   Q15024; Q96E72;
DE   RecName: Full=Exosome complex component RRP42;
DE   AltName: Full=Exosome component 7;
DE   AltName: Full=Ribosomal RNA-processing protein 42;
DE   AltName: Full=p8;
GN   Name=EXOSC7; Synonyms=KIAA0116, RRP42;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0006401; P:RNA catabolic process; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; TAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; TAS:UniProtKB.
//
ID   EXOS8_HUMAN             Reviewed;         276 AA.
AC   Q96B26; O43480; Q5TBA5;
DE   RecName: Full=Exosome complex component RRP43;
DE   AltName: Full=Exosome component 8;
DE   AltName: Full=Opa-interacting protein 2;
DE            Short=OIP-2;
DE   AltName: Full=Ribosomal RNA-processing protein 43;
DE   AltName: Full=p9;
GN   Name=EXOSC8; Synonyms=OIP2, RRP43;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   EXOS9_HUMAN             Reviewed;         439 AA.
AC   Q06265; Q12883; Q4W5P5; Q86Y41; Q86Y48;
DE   RecName: Full=Exosome complex component RRP45;
DE   AltName: Full=Autoantigen PM/Scl 1;
DE   AltName: Full=Exosome component 9;
DE   AltName: Full=P75 polymyositis-scleroderma overlap syndrome-associated autoantigen;
DE   AltName: Full=Polymyositis/scleroderma autoantigen 1;
DE   AltName: Full=Polymyositis/scleroderma autoantigen 75 kDa;
DE            Short=PM/Scl-75;
GN   Name=EXOSC9; Synonyms=PMSCL1;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0071028; P:nuclear mRNA surveillance; IMP:UniProtKB.
DR   GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; NAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; NAS:UniProtKB.
//
ID   EXOSX_HUMAN             Reviewed;         885 AA.
AC   Q01780; B1AKQ0; B1AKQ1; Q15158;
DE   RecName: Full=Exosome component 10;
DE            EC=3.1.13.-;
DE   AltName: Full=Autoantigen PM/Scl 2;
DE   AltName: Full=P100 polymyositis-scleroderma overlap syndrome-associated autoantigen;
DE   AltName: Full=Polymyositis/scleroderma autoantigen 100 kDa;
DE            Short=PM/Scl-100;
DE   AltName: Full=Polymyositis/scleroderma autoantigen 2;
GN   Name=EXOSC10; Synonyms=PMSCL, PMSCL2, RRP6;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0004532; F:exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071034; P:CUT catabolic process; IMP:UniProtKB.
DR   GO; GO:0009048; P:dosage compensation by inactivation of X chromosome; IEA:Ensembl.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
DR   GO; GO:0071028; P:nuclear mRNA surveillance; IMP:UniProtKB.
DR   GO; GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0071048; P:nuclear retention of unspliced pre-mRNA at the site of transcription; IMP:UniProtKB.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
//
ID   EXPH5_HUMAN             Reviewed;        1989 AA.
AC   Q8NEV8; Q2KHM1; Q9Y4D6;
DE   RecName: Full=Exophilin-5;
DE   AltName: Full=Synaptotagmin-like protein homolog lacking C2 domains b;
DE            Short=SlaC2-b;
DE            Short=Slp homolog lacking C2 domains b;
GN   Name=EXPH5; Synonyms=KIAA0624, SLAC2B;
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0003334; P:keratinocyte development; IMP:UniProtKB.
DR   GO; GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
//
ID   EXT1_HUMAN              Reviewed;         746 AA.
AC   Q16394; B2R7V2; Q9BVI9;
DE   RecName: Full=Exostosin-1;
DE            EC=2.4.1.224;
DE            EC=2.4.1.225;
DE   AltName: Full=Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;
DE   AltName: Full=Multiple exostoses protein 1;
DE   AltName: Full=Putative tumor suppressor protein EXT1;
GN   Name=EXT1;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0042328; F:heparan sulfate N-acetylglucosaminyltransferase activity; NAS:BHF-UCL.
DR   GO; GO:0050509; F:N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0033692; P:cellular polysaccharide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0072498; P:embryonic skeletal joint development; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IMP:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   EXT2_HUMAN              Reviewed;         718 AA.
AC   Q93063; B2R5Z6; C9JU51; J3KPT2; O15288;
DE   RecName: Full=Exostosin-2;
DE            EC=2.4.1.224;
DE            EC=2.4.1.225;
DE   AltName: Full=Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;
DE   AltName: Full=Multiple exostoses protein 2;
DE   AltName: Full=Putative tumor suppressor protein EXT2;
GN   Name=EXT2;
DR   GO; GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0042328; F:heparan sulfate N-acetylglucosaminyltransferase activity; NAS:BHF-UCL.
DR   GO; GO:0050509; F:N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; NAS:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IDA:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0033692; P:cellular polysaccharide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IMP:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   EXTL1_HUMAN             Reviewed;         676 AA.
AC   Q92935; Q6GSC1;
DE   RecName: Full=Exostosin-like 1;
DE            EC=2.4.1.224;
DE   AltName: Full=Exostosin-L;
DE   AltName: Full=Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;
DE   AltName: Full=Multiple exostosis-like protein;
GN   Name=EXTL1; Synonyms=EXTL;
DR   GO; GO:0050508; F:glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   EXTL2_HUMAN             Reviewed;         330 AA.
AC   Q9UBQ6; B2R795; D3DT60;
DE   RecName: Full=Exostosin-like 2;
DE            EC=2.4.1.223;
DE   AltName: Full=Alpha-1,4-N-acetylhexosaminyltransferase EXTL2;
DE   AltName: Full=Alpha-GalNAcT EXTL2;
DE   AltName: Full=EXT-related protein 2;
DE   AltName: Full=Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;
DE   Contains:
DE     RecName: Full=Processed exostosin-like 2;
GN   Name=EXTL2; Synonyms=EXTR2;
DR   GO; GO:0035248; F:alpha-1,4-N-acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0001888; F:glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IDA:UniProtKB.
DR   GO; GO:0019276; P:UDP-N-acetylgalactosamine metabolic process; IDA:UniProtKB.
//
ID   EXTL3_HUMAN             Reviewed;         919 AA.
AC   O43909; D3DST8; O00225; Q53XT3;
DE   RecName: Full=Exostosin-like 3;
DE            EC=2.4.1.223;
DE   AltName: Full=EXT-related protein 1;
DE   AltName: Full=Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase;
DE   AltName: Full=Hereditary multiple exostoses gene isolog;
DE   AltName: Full=Multiple exostosis-like protein 3;
DE   AltName: Full=Putative tumor suppressor protein EXTL3;
GN   Name=EXTL3; Synonyms=EXTL1L, EXTR1, KIAA0519;
DR   GO; GO:0001888; F:glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
//
ID   EYA2_HUMAN              Reviewed;         538 AA.
AC   O00167; Q5JSW8; Q86U84; Q96CV6; Q96H97; Q99503; Q99812; Q9BWF6;
AC   Q9H4S3; Q9H4S9; Q9NPZ4; Q9UIX7;
DE   RecName: Full=Eyes absent homolog 2;
DE            EC=3.1.3.48;
GN   Name=EYA2; Synonyms=EAB1;
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0016576; P:histone dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0007501; P:mesodermal cell fate specification; TAS:ProtInc.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0014706; P:striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EYA1_HUMAN              Reviewed;         592 AA.
AC   Q99502; A6NHQ0; G5E9R4; Q0P516; Q8WX80;
DE   RecName: Full=Eyes absent homolog 1;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
GN   Name=EYA1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:Ensembl.
DR   GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IEA:Ensembl.
DR   GO; GO:0016576; P:histone dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0071600; P:otic vesicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0042473; P:outer ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0072513; P:positive regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0016925; P:protein sumoylation; ISS:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0014706; P:striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EYA3_HUMAN              Reviewed;         573 AA.
AC   Q99504; A8K190; B4DIR7; B4DNZ7; O95463; Q8IVX7; Q99813;
DE   RecName: Full=Eyes absent homolog 3;
DE            EC=3.1.3.48;
GN   Name=EYA3;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0016576; P:histone dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   EYA4_HUMAN              Reviewed;         639 AA.
AC   O95677; B7Z7F7; O95464; O95679; Q8IW39; Q9NTR7;
DE   RecName: Full=Eyes absent homolog 4;
DE            EC=3.1.3.48;
GN   Name=EYA4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   EYS_HUMAN               Reviewed;        3165 AA.
AC   Q5T1H1; A2RUR2; A8MVE7; B7TYK8; B7UUQ3; B7ZBE7; B7ZBE8; B7ZBR3;
AC   B9ZVD2; Q5SZM4; Q5T3C8; Q5T669; Q5TEL3; Q5TEL4; Q5VVG4; Q6UY05;
AC   Q9H557; Q9NQ15;
DE   RecName: Full=Protein eyes shut homolog;
DE   AltName: Full=Epidermal growth factor-like protein 10;
DE            Short=EGF-like protein 10;
DE   AltName: Full=Epidermal growth factor-like protein 11;
DE            Short=EGF-like protein 11;
DE   AltName: Full=Protein spacemaker homolog;
DE   Flags: Precursor;
GN   Name=EYS; Synonyms=C6orf178, C6orf179, C6orf180, EGFL10, EGFL11, SPAM;
GN   ORFNames=UNQ9424/PRO34591;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProt.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IMP:UniProt.
//
ID   EZH1_HUMAN              Reviewed;         747 AA.
AC   Q92800; A6NCH6; B4DIJ1; B4DIZ7; B4DSS2; B4E3R7; O43287; Q14459;
AC   Q53XP3;
DE   RecName: Full=Histone-lysine N-methyltransferase EZH1;
DE            EC=2.1.1.43;
DE   AltName: Full=ENX-2;
DE   AltName: Full=Enhancer of zeste homolog 1;
GN   Name=EZH1; Synonyms=KIAA0388;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EZH2_HUMAN              Reviewed;         746 AA.
AC   Q15910; B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; Q15755; Q75MG3; Q92857;
AC   Q96FI6;
DE   RecName: Full=Histone-lysine N-methyltransferase EZH2;
DE            EC=2.1.1.43;
DE   AltName: Full=ENX-1;
DE   AltName: Full=Enhancer of zeste homolog 2;
DE   AltName: Full=Lysine N-methyltransferase 6;
GN   Name=EZH2; Synonyms=KMT6;
DR   GuidetoPHARMACOLOGY; 2654; -.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:MGI.
DR   GO; GO:0046976; F:histone methyltransferase activity (H3-K27 specific); TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0021695; P:cerebellar cortex development; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; TAS:ProtInc.
DR   GO; GO:0070314; P:G1 to G0 transition; IEA:Ensembl.
DR   GO; GO:0070734; P:histone H3-K27 methylation; IDA:UniProtKB.
DR   GO; GO:0045605; P:negative regulation of epidermal cell differentiation; IEA:Ensembl.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:UniProtKB.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051154; P:negative regulation of striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0014013; P:regulation of gliogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   EZRI_HUMAN              Reviewed;         586 AA.
AC   P15311; E1P5A8; P23714; Q4VX75; Q96CU8; Q9NSJ4;
DE   RecName: Full=Ezrin;
DE   AltName: Full=Cytovillin;
DE   AltName: Full=Villin-2;
DE   AltName: Full=p81;
GN   Name=EZR; Synonyms=VIL2;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IGI:UniProt.
DR   GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IEA:Ensembl.
DR   GO; GO:0046847; P:filopodium assembly; IEA:Ensembl.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IEP:BHF-UCL.
DR   GO; GO:0022614; P:membrane to membrane docking; IEP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IGI:UniProt.
DR   GO; GO:0031623; P:receptor internalization; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
//
ID   F101A_HUMAN             Reviewed;         216 AA.
AC   Q6ZTI6; A5D8T5;
DE   RecName: Full=Protein FAM101A;
GN   Name=FAM101A;
//
ID   F101B_HUMAN             Reviewed;         214 AA.
AC   Q8N5W9;
DE   RecName: Full=Protein FAM101B;
GN   Name=FAM101B;
DR   GO; GO:0031005; F:filamin binding; IDA:MGI.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
//
ID   F102A_HUMAN             Reviewed;         384 AA.
AC   Q5T9C2; A2A329; Q8TEL4;
DE   RecName: Full=Protein FAM102A;
DE   AltName: Full=Early estrogen-induced gene 1 protein;
GN   Name=FAM102A; Synonyms=C9orf132, EEIG1;
//
ID   F102B_HUMAN             Reviewed;         360 AA.
AC   Q5T8I3; A1L1A1; B0QZ46; B0QZ47; Q68DH7;
DE   RecName: Full=Protein FAM102B;
GN   Name=FAM102B;
//
ID   F104A_HUMAN             Reviewed;         186 AA.
AC   Q969W3; B4E339;
DE   RecName: Full=Protein FAM104A;
GN   Name=FAM104A;
//
ID   F105A_HUMAN             Reviewed;         356 AA.
AC   Q9NUU6; Q53H50; Q9H037;
DE   RecName: Full=Inactive ubiquitin thioesterase FAM105A;
GN   Name=FAM105A;
//
ID   F104B_HUMAN             Reviewed;         115 AA.
AC   Q5XKR9; A6NEH1; B4DSV6; D6R9S5; D6RDJ5; E9PH40; Q8WVU5; Q9BRA1;
DE   RecName: Full=Protein FAM104B;
GN   Name=FAM104B; Synonyms=CXorf44;
//
ID   F106A_HUMAN             Reviewed;         169 AA.
AC   Q4KMX7; Q9HAD1;
DE   RecName: Full=Protein FAM106A;
GN   Name=FAM106A;
//
ID   F106B_HUMAN             Reviewed;         169 AA.
AC   A6NHU5;
DE   RecName: Full=Protein FAM106B;
GN   Name=FAM106B;
//
ID   F107A_HUMAN             Reviewed;         144 AA.
AC   O95990; B3KNQ4; B7ZAY5; J3KR61; Q96NH4;
DE   RecName: Full=Protein FAM107A;
DE   AltName: Full=Down-regulated in renal cell carcinoma 1;
DE   AltName: Full=Protein TU3A;
GN   Name=FAM107A; Synonyms=DRR1, TU3A;
DR   GO; GO:0001558; P:regulation of cell growth; IDA:UniProtKB.
//
ID   F106C_HUMAN             Reviewed;         169 AA.
AC   P0CH98;
DE   RecName: Full=Putative protein FAM106C;
DE   AltName: Full=FAM106C pseudogene;
GN   Name=FAM106CP; Synonyms=FAM106C;
//
ID   F107B_HUMAN             Reviewed;         131 AA.
AC   Q9H098; A8K1P4; D3DRT2; Q5T9K7; Q5T9K8; Q6ZSI4;
DE   RecName: Full=Protein FAM107B;
GN   Name=FAM107B; Synonyms=C10orf45;
//
ID   F10A1_HUMAN             Reviewed;         369 AA.
AC   P50502; O14999; Q2TU77;
DE   RecName: Full=Hsc70-interacting protein;
DE            Short=Hip;
DE   AltName: Full=Aging-associated protein 2;
DE   AltName: Full=Progesterone receptor-associated p48 protein;
DE   AltName: Full=Protein FAM10A1;
DE   AltName: Full=Putative tumor suppressor ST13;
DE   AltName: Full=Renal carcinoma antigen NY-REN-33;
DE   AltName: Full=Suppression of tumorigenicity 13 protein;
GN   Name=ST13; Synonyms=AAG2, FAM10A1, HIP, SNC6;
DR   GO; GO:0032564; F:dATP binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; TAS:ProtInc.
DR   GO; GO:0070389; P:chaperone cofactor-dependent protein refolding; IEA:Ensembl.
DR   GO; GO:0061084; P:negative regulation of protein refolding; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
//
ID   F10A5_HUMAN             Reviewed;         369 AA.
AC   Q8NFI4;
DE   RecName: Full=Putative protein FAM10A5;
DE   AltName: Full=Suppression of tumorigenicity 13 pseudogene 5;
GN   Name=ST13P5; Synonyms=FAM10A5;
//
ID   F10C1_HUMAN             Reviewed;         315 AA.
AC   Q70Z53; C9JCR4; C9JCR5; C9JMY4; Q70Z49; Q70Z50; Q70Z51; Q70Z52;
AC   Q8N293; Q8WVH5; Q96JQ8;
DE   RecName: Full=Protein FRA10AC1;
GN   Name=FRA10AC1; Synonyms=C10orf4; ORFNames=PRO2972;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   F110C_HUMAN             Reviewed;         321 AA.
AC   Q1W6H9;
DE   RecName: Full=Protein FAM110C;
GN   Name=FAM110C;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0060491; P:regulation of cell projection assembly; IMP:UniProtKB.
//
ID   F110D_HUMAN             Reviewed;         271 AA.
AC   Q8TAY7; A8K3V0; Q9H7Z4;
DE   RecName: Full=Protein FAM110D;
GN   Name=FAM110D; Synonyms=GRRP1;
//
ID   F111A_HUMAN             Reviewed;         611 AA.
AC   Q96PZ2; A8K5Y8; Q5RKS9; Q5XKM2; Q68DK9; Q6IPR7; Q9H5Y1;
DE   RecName: Full=Protein FAM111A;
GN   Name=FAM111A; Synonyms=KIAA1895;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0000087; P:mitotic M phase; IEP:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   F110B_HUMAN             Reviewed;         370 AA.
AC   Q8TC76; Q5BM08; Q9Y4K2;
DE   RecName: Full=Protein FAM110B;
GN   Name=FAM110B; Synonyms=C8orf72;
//
ID   F110A_HUMAN             Reviewed;         295 AA.
AC   Q9BQ89; D3DVW2; Q5R1M7;
DE   RecName: Full=Protein FAM110A;
GN   Name=FAM110A; Synonyms=C20orf55, F10;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   F1142_HUMAN             Reviewed;         505 AA.
AC   Q9NRY5; B2R8D8; Q9H7E0;
DE   RecName: Full=Protein FAM114A2;
GN   Name=FAM114A2; Synonyms=C5orf3;
DR   GO; GO:0017076; F:purine nucleotide binding; NAS:UniProtKB.
//
ID   F111B_HUMAN             Reviewed;         734 AA.
AC   Q6SJ93; B4E2G2; Q6P661;
DE   RecName: Full=Protein FAM111B;
DE   AltName: Full=Cancer-associated nucleoprotein;
GN   Name=FAM111B; Synonyms=CANP;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   F115A_HUMAN             Reviewed;         921 AA.
AC   Q9Y4C2; A8K6E0; Q75KM8; Q75KM9; Q7L665; Q9BW63;
DE   RecName: Full=Protein FAM115A;
GN   Name=FAM115A; Synonyms=KIAA0738;
//
ID   F115C_HUMAN             Reviewed;         919 AA.
AC   A6NFQ2; B4DK02; Q14D25; Q17RQ4; Q8IWQ0; Q8NF84;
DE   RecName: Full=Protein FAM115C;
DE   AltName: Full=Protein FAM139A;
GN   Name=FAM115C; Synonyms=FAM139A;
//
ID   F117A_HUMAN             Reviewed;         453 AA.
AC   Q9C073;
DE   RecName: Full=Protein FAM117A;
DE   AltName: Full=C/EBP-induced protein;
GN   Name=FAM117A;
//
ID   F117B_HUMAN             Reviewed;         589 AA.
AC   Q6P1L5; Q53QZ5; Q585T9; Q8N8W1; Q96Q34;
DE   RecName: Full=Protein FAM117B;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 13 protein;
GN   Name=FAM117B; Synonyms=ALS2CR13;
//
ID   F118A_HUMAN             Reviewed;         357 AA.
AC   Q9NWS6; B3KWG4; Q5TII5; Q96CY3;
DE   RecName: Full=Protein FAM118A;
GN   Name=FAM118A; Synonyms=C22orf8;
//
ID   F118B_HUMAN             Reviewed;         351 AA.
AC   Q9BPY3; Q9H7B0;
DE   RecName: Full=Protein FAM118B;
GN   Name=FAM118B;
//
ID   F120A_HUMAN             Reviewed;        1118 AA.
AC   Q9NZB2; A6NGU0; C4AMC6; O60649; Q14688; Q4VXF4; Q4VXF5; Q4VXG2;
AC   Q86V69; Q96I21; Q9NZB1;
DE   RecName: Full=Constitutive coactivator of PPAR-gamma-like protein 1;
DE   AltName: Full=Oxidative stress-associated Src activator;
DE   AltName: Full=Protein FAM120A;
GN   Name=FAM120A; Synonyms=C9orf10, KIAA0183, OSSA;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   F120B_HUMAN             Reviewed;         910 AA.
AC   Q96EK7; Q86V68; Q96JI9;
DE   RecName: Full=Constitutive coactivator of peroxisome proliferator-activated receptor gamma;
DE            Short=Constitutive coactivator of PPAR-gamma;
DE            Short=Constitutive coactivator of PPARG;
DE   AltName: Full=PPARG constitutive coactivator 1;
DE            Short=PGCC1;
DE   AltName: Full=Protein FAM120B;
GN   Name=FAM120B; Synonyms=CCPG, KIAA1838;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   F120C_HUMAN             Reviewed;        1096 AA.
AC   Q9NX05; B2RMT7;
DE   RecName: Full=Constitutive coactivator of PPAR-gamma-like protein 2;
DE   AltName: Full=Protein FAM120C;
DE   AltName: Full=Tumor antigen BJ-HCC-21;
GN   Name=FAM120C; Synonyms=CXorf17;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   F120S_HUMAN             Reviewed;         256 AA.
AC   Q5T036; A6NN20;
DE   RecName: Full=Putative FAM120A opposite strand protein;
GN   Name=FAM120AOS; Synonyms=C9orf10OS;
//
ID   F122A_HUMAN             Reviewed;         287 AA.
AC   Q96E09;
DE   RecName: Full=Protein FAM122A;
GN   Name=FAM122A; Synonyms=C9orf42;
//
ID   F122B_HUMAN             Reviewed;         247 AA.
AC   Q7Z309; A8K902; Q6PIM2; Q6ZU47; Q6ZV64; Q6ZVE4; Q8TB75;
DE   RecName: Full=Protein FAM122B;
GN   Name=FAM122B;
//
ID   F124B_HUMAN             Reviewed;         455 AA.
AC   Q9H5Z6; A6NNC7; Q8NBZ4; Q8TAV7;
DE   RecName: Full=Protein FAM124B;
GN   Name=FAM124B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   F124A_HUMAN             Reviewed;         546 AA.
AC   Q86V42; A2A324; Q8N8P9; Q8NE66; Q96NJ9;
DE   RecName: Full=Protein FAM124A;
GN   Name=FAM124A;
//
ID   F126B_HUMAN             Reviewed;         530 AA.
AC   Q8IXS8; B2RCG7; Q4ZG87; Q53TX6;
DE   RecName: Full=Protein FAM126B;
GN   Name=FAM126B;
//
ID   F127B_HUMAN             Reviewed;         113 AA.
AC   Q9BWD3; A2A2V9; Q8TBU2;
DE   RecName: Full=Protein FAM127B;
DE   AltName: Full=Mammalian retrotransposon derived protein 8A;
GN   Name=FAM127B; Synonyms=CXX1B, MAR8A;
//
ID   F127A_HUMAN             Reviewed;         113 AA.
AC   A6ZKI3;
DE   RecName: Full=Protein FAM127A;
DE   AltName: Full=Mammalian retrotransposon derived protein 8C;
GN   Name=FAM127A; Synonyms=CXX1, MAR8, MAR8C, MART8;
//
ID   F127C_HUMAN             Reviewed;         113 AA.
AC   Q17RB0;
DE   RecName: Full=Protein FAM127C;
DE   AltName: Full=Mammalian retrotransposon derived protein 8B;
GN   Name=FAM127C; Synonyms=CXX1C, MAR8B;
//
ID   F131B_HUMAN             Reviewed;         332 AA.
AC   Q86XD5; A4D2H6; A6NDW3; A8K605; B8ZZN2; D3DXE3; J3KQX2; Q7L0D6;
AC   Q86T97;
DE   RecName: Full=Protein FAM131B;
GN   Name=FAM131B; Synonyms=KIAA0773;
//
ID   F131C_HUMAN             Reviewed;         280 AA.
AC   Q96AQ9; Q5T5Q5; Q8N3X3; Q8N9P9;
DE   RecName: Full=Protein FAM131C;
GN   Name=FAM131C; Synonyms=C1orf117;
//
ID   F132B_HUMAN             Reviewed;         354 AA.
AC   Q4G0M1;
DE   RecName: Full=Protein FAM132B;
DE   AltName: Full=Complement C1q tumor necrosis factor-related protein 15;
DE   AltName: Full=Myonectin;
DE   Flags: Precursor;
GN   Name=FAM132B; Synonyms=C1QTNF15, CTRP15;
DR   GO; GO:2000193; P:positive regulation of fatty acid transport; IEA:Ensembl.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; IEA:Ensembl.
//
ID   F132A_HUMAN             Reviewed;         302 AA.
AC   Q5T7M4; Q5EBL5;
DE   RecName: Full=Protein FAM132A;
DE   Flags: Precursor;
GN   Name=FAM132A; Synonyms=C1QDC2, CTRP12;
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
//
ID   F131A_HUMAN             Reviewed;         335 AA.
AC   Q6UXB0; D3DNT6; G5E9B1; Q8TA84;
DE   RecName: Full=Protein FAM131A;
DE   Flags: Precursor;
GN   Name=FAM131A; Synonyms=C3orf40; ORFNames=UNQ715/PRO1378;
//
ID   F133B_HUMAN             Reviewed;         247 AA.
AC   Q5BKY9; B2R994; Q05D67; Q6P5S6; Q8N0W8;
DE   RecName: Full=Protein FAM133B;
GN   Name=FAM133B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   F133A_HUMAN             Reviewed;         248 AA.
AC   Q8N9E0;
DE   RecName: Full=Protein FAM133A;
GN   Name=FAM133A;
//
ID   F134A_HUMAN             Reviewed;         543 AA.
AC   Q8NC44; Q6P1P5; Q9H0K7;
DE   RecName: Full=Protein FAM134A;
GN   Name=FAM134A; Synonyms=C2orf17;
//
ID   F134B_HUMAN             Reviewed;         497 AA.
AC   Q9H6L5; Q69YN8; Q9H6K6; Q9H764; Q9NXM8;
DE   RecName: Full=Protein FAM134B;
GN   Name=FAM134B;
DR   GO; GO:0019233; P:sensory perception of pain; IMP:UniProtKB.
//
ID   F134C_HUMAN             Reviewed;         466 AA.
AC   Q86VR2;
DE   RecName: Full=Protein FAM134C;
GN   Name=FAM134C;
//
ID   F135A_HUMAN             Reviewed;        1515 AA.
AC   Q9P2D6; A2RRQ5; Q3C0H3; Q5JXK0; Q5JXK1; Q68DW0; Q6P081; Q9H0F2;
AC   Q9NU48; Q9NUQ5; Q9NXL5;
DE   RecName: Full=Protein FAM135A;
GN   Name=FAM135A; Synonyms=KIAA1411;
//
ID   F135B_HUMAN             Reviewed;        1406 AA.
AC   Q49AJ0; B5MDB3; O95879; Q2WGJ7; Q3KP46;
DE   RecName: Full=Protein FAM135B;
GN   Name=FAM135B; Synonyms=C8orfK32;
//
ID   F136A_HUMAN             Reviewed;         138 AA.
AC   Q96C01; Q96SS3;
DE   RecName: Full=Protein FAM136A;
GN   Name=FAM136A;
//
ID   F13A_HUMAN              Reviewed;         732 AA.
AC   P00488; Q59HA7; Q8N6X2; Q96P24; Q9BX29;
DE   RecName: Full=Coagulation factor XIII A chain;
DE            Short=Coagulation factor XIIIa;
DE            EC=2.3.2.13;
DE   AltName: Full=Protein-glutamine gamma-glutamyltransferase A chain;
DE   AltName: Full=Transglutaminase A chain;
DE   Flags: Precursor;
GN   Name=F13A1; Synonyms=F13A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   F13B_HUMAN              Reviewed;         661 AA.
AC   P05160; A8K3E5; Q5VYL5;
DE   RecName: Full=Coagulation factor XIII B chain;
DE   AltName: Full=Fibrin-stabilizing factor B subunit;
DE   AltName: Full=Protein-glutamine gamma-glutamyltransferase B chain;
DE   AltName: Full=Transglutaminase B chain;
DE   Flags: Precursor;
GN   Name=F13B;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
//
ID   F149A_HUMAN             Reviewed;         773 AA.
AC   A5PLN7; B5MDB8; Q2TAN6; Q7Z2S5; Q9Y4T9;
DE   RecName: Full=Protein FAM149A;
GN   Name=FAM149A; ORFNames=MST119;
//
ID   F150A_HUMAN             Reviewed;         129 AA.
AC   Q6UXT8;
DE   RecName: Full=Protein FAM150A;
DE   Flags: Precursor;
GN   Name=FAM150A; ORFNames=UNQ9433/PRO34745;
//
ID   F149B_HUMAN             Reviewed;         582 AA.
AC   Q96BN6; Q9Y2I0;
DE   RecName: Full=Protein FAM149B1;
GN   Name=FAM149B1; Synonyms=KIAA0974;
//
ID   F151A_HUMAN             Reviewed;         585 AA.
AC   Q8WW52; Q5VUG5; Q6DKH5; Q6UWV0; Q8NAX9; Q96KY5;
DE   RecName: Full=Protein FAM151A;
GN   Name=FAM151A; Synonyms=C1orf179; ORFNames=UNQ3034/PRO9836;
//
ID   F150B_HUMAN             Reviewed;         152 AA.
AC   Q6UX46; B5MC76;
DE   RecName: Full=Protein FAM150B;
DE   Flags: Precursor;
GN   Name=FAM150B; ORFNames=UNQ542/PRO1097;
//
ID   F151B_HUMAN             Reviewed;         276 AA.
AC   Q6UXP7; A2RRE4;
DE   RecName: Full=Protein FAM151B;
GN   Name=FAM151B; ORFNames=UNQ9217/PRO28685;
//
ID   F153A_HUMAN             Reviewed;         310 AA.
AC   Q9UHL3; A8K0F3; O94852;
DE   RecName: Full=Protein FAM153A;
DE   AltName: Full=Renal carcinoma antigen NY-REN-7;
GN   Name=FAM153A; Synonyms=KIAA0752;
//
ID   F153B_HUMAN             Reviewed;         387 AA.
AC   P0C7A2; A8MTI1;
DE   RecName: Full=Protein FAM153B;
GN   Name=FAM153B;
//
ID   F153C_HUMAN             Reviewed;         144 AA.
AC   Q494X1; A4IF33; B2RUV5; B7ZW12;
DE   RecName: Full=Protein FAM153C;
GN   Name=FAM153C;
//
ID   F154A_HUMAN             Reviewed;         474 AA.
AC   Q8IYX7; Q5VY58;
DE   RecName: Full=Protein FAM154A;
GN   Name=FAM154A; Synonyms=C9orf138;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   F154B_HUMAN             Reviewed;         398 AA.
AC   Q658L1;
DE   RecName: Full=Protein FAM154B;
GN   Name=FAM154B;
//
ID   F155A_HUMAN             Reviewed;         458 AA.
AC   B1AL88; B2RUV1; B7Z334;
DE   RecName: Full=Transmembrane protein FAM155A;
GN   Name=FAM155A;
//
ID   F157A_HUMAN             Reviewed;         383 AA.
AC   C9JC47;
DE   RecName: Full=Putative protein FAM157A;
GN   Name=FAM157A;
//
ID   F157B_HUMAN             Reviewed;         384 AA.
AC   P0CG42;
DE   RecName: Full=Putative protein FAM157B;
GN   Name=FAM157B;
//
ID   F155B_HUMAN             Reviewed;         473 AA.
AC   O75949; B1ALV6; B9EGK1; D3DVU1;
DE   RecName: Full=Transmembrane protein FAM155B;
DE   AltName: Full=Protein TED;
DE   AltName: Full=Transmembrane protein 28;
GN   Name=FAM155B; Synonyms=TED, TMEM28;
//
ID   F157C_HUMAN             Reviewed;         387 AA.
AC   P0CG43;
DE   RecName: Full=Putative protein FAM157C;
GN   Name=FAM157C;
//
ID   F159A_HUMAN             Reviewed;         190 AA.
AC   Q6UWV7; Q6ZRG4;
DE   RecName: Full=Membrane protein FAM159A;
GN   Name=FAM159A; ORFNames=UNQ2783/PRO7171;
//
ID   F159B_HUMAN             Reviewed;         160 AA.
AC   A6NKW6;
DE   RecName: Full=Membrane protein FAM159B;
GN   Name=FAM159B;
//
ID   F161A_HUMAN             Reviewed;         660 AA.
AC   Q3B820; B4DJV7; Q9H8R2;
DE   RecName: Full=Protein FAM161A;
GN   Name=FAM161A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   F161B_HUMAN             Reviewed;         647 AA.
AC   Q96MY7; B7Z882; J3KNA2;
DE   RecName: Full=Protein FAM161B;
GN   Name=FAM161B; Synonyms=C14orf44;
//
ID   F162A_HUMAN             Reviewed;         154 AA.
AC   Q96A26; Q9NRN6; Q9UJX8;
DE   RecName: Full=Protein FAM162A;
DE   AltName: Full=E2-induced gene 5 protein;
DE   AltName: Full=Growth and transformation-dependent protein;
DE            Short=HGTD-P;
GN   Name=FAM162A; Synonyms=C3orf28, E2IG5; ORFNames=DC16, FWP001;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0006927; P:transformed cell apoptotic process; IDA:UniProtKB.
//
ID   F162B_HUMAN             Reviewed;         162 AA.
AC   Q5T6X4; Q8IXW8;
DE   RecName: Full=Protein FAM162B;
GN   Name=FAM162B; Synonyms=C6orf189;
//
ID   F163A_HUMAN             Reviewed;         167 AA.
AC   Q96GL9; A8K8R7;
DE   RecName: Full=Protein FAM163A;
DE   AltName: Full=Cebelin;
DE   AltName: Full=Neuroblastoma-derived secretory protein;
GN   Name=FAM163A; Synonyms=C1orf76, NDSP;
//
ID   F163B_HUMAN             Reviewed;         166 AA.
AC   P0C2L3; B2RUZ5;
DE   RecName: Full=Protein FAM163B;
GN   Name=FAM163B; Synonyms=C9orf166;
//
ID   F166A_HUMAN             Reviewed;         317 AA.
AC   Q6J272; A6NND9; Q8N830;
DE   RecName: Full=Protein FAM166A;
GN   Name=FAM166A; ORFNames=HSD46;
//
ID   F166B_HUMAN             Reviewed;         275 AA.
AC   A8MTA8; A1L3B2; B7ZBJ0;
DE   RecName: Full=Protein FAM166B;
GN   Name=FAM166B;
//
ID   F167A_HUMAN             Reviewed;         214 AA.
AC   Q96KS9; A8K3T9; Q3SXY1; Q3SXY3; Q8N3M3; Q9NSR0;
DE   RecName: Full=Protein FAM167A;
GN   Name=FAM167A; Synonyms=C8orf13;
//
ID   F167B_HUMAN             Reviewed;         163 AA.
AC   Q9BTA0; Q5TDH6;
DE   RecName: Full=Protein FAM167B;
GN   Name=FAM167B; Synonyms=C1orf90;
//
ID   F168A_HUMAN             Reviewed;         244 AA.
AC   Q92567; A2ICY2; A2ID81; Q86UG2;
DE   RecName: Full=Protein FAM168A;
DE   AltName: Full=Tongue cancer chemotherapy resistance-associated protein 1;
GN   Name=FAM168A; Synonyms=KIAA0280, TCRP1;
//
ID   F168B_HUMAN             Reviewed;         195 AA.
AC   A1KXE4; Q2TAZ6; Q6NZ40;
DE   RecName: Full=Myelin-associated neurite-outgrowth inhibitor;
DE            Short=Mani;
DE   AltName: Full=p20;
GN   Name=FAM168B; Synonyms=KIAA0280L, MANI;
//
ID   F169A_HUMAN             Reviewed;         670 AA.
AC   Q9Y6X4; A8K1T9; Q6MZT0; Q9H989;
DE   RecName: Full=Soluble lamin-associated protein of 75 kDa;
DE            Short=SLAP75;
DE   AltName: Full=Protein FAM169A;
GN   Name=FAM169A; Synonyms=KIAA0888;
//
ID   F169B_HUMAN             Reviewed;         192 AA.
AC   Q8N8A8; B5MDL8;
DE   RecName: Full=Protein FAM169B;
GN   Name=FAM169B; Synonyms=KIAA0888L;
//
ID   F16A1_HUMAN             Reviewed;        1040 AA.
AC   Q05DH4; Q6ZUS2;
DE   RecName: Full=Protein FAM160A1;
GN   Name=FAM160A1;
//
ID   F16A2_HUMAN             Reviewed;         972 AA.
AC   Q8N612; Q9C0A4; Q9H0N3; Q9H624;
DE   RecName: Full=FTS and Hook-interacting protein;
DE            Short=FHIP;
DE   AltName: Full=Protein FAM160A2;
GN   Name=FAM160A2; Synonyms=C11orf56, KIAA1759;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   F16B1_HUMAN             Reviewed;         765 AA.
AC   Q5W0V3; Q5H9P7; Q5W0V2; Q8IY76; Q9HCH2;
DE   RecName: Full=Protein FAM160B1;
GN   Name=FAM160B1; Synonyms=KIAA1600;
//
ID   F16B2_HUMAN             Reviewed;         743 AA.
AC   Q86V87; B2RDQ5; B3KNX1; Q2M211; Q71JB5; Q7L3J6; Q969T0; Q9H6W4;
DE   RecName: Full=Protein FAM160B2;
DE   AltName: Full=Retinoic acid-induced protein 16;
GN   Name=FAM160B2; Synonyms=RAI16; ORFNames=FP13191;
//
ID   F16P1_HUMAN             Reviewed;         338 AA.
AC   P09467; O75571; Q53F94; Q96E46;
DE   RecName: Full=Fructose-1,6-bisphosphatase 1;
DE            Short=FBPase 1;
DE            EC=3.1.3.11;
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase 1;
DE   AltName: Full=Liver FBPase;
GN   Name=FBP1; Synonyms=FBP;
DR   GO; GO:0016208; F:AMP binding; IDA:UniProtKB.
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IMP:UniProtKB.
DR   GO; GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0071286; P:cellular response to magnesium ion; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006000; P:fructose metabolic process; TAS:ProtInc.
DR   GO; GO:0006094; P:gluconeogenesis; IMP:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045820; P:negative regulation of glycolytic process; IDA:UniProtKB.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   F16P2_HUMAN             Reviewed;         339 AA.
AC   O00757; Q17R39; Q6FI53;
DE   RecName: Full=Fructose-1,6-bisphosphatase isozyme 2;
DE            Short=FBPase 2;
DE            EC=3.1.3.11;
DE   AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase 2;
GN   Name=FBP2;
DR   GO; GO:0042132; F:fructose 1,6-bisphosphate 1-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006000; P:fructose metabolic process; TAS:ProtInc.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   F170A_HUMAN             Reviewed;         330 AA.
AC   A1A519; Q66LM8; Q7Z4V2; Q8IW94;
DE   RecName: Full=Protein FAM170A;
DE   AltName: Full=Zinc finger domain-containing protein;
DE   AltName: Full=Zinc finger protein ZNFD;
GN   Name=FAM170A; Synonyms=ZNFD;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   F1711_HUMAN             Reviewed;         890 AA.
AC   Q5VUB5; D3DRT9; Q32M49; Q8N4I0;
DE   RecName: Full=Protein FAM171A1;
DE   AltName: Full=Astroprincin;
DE   Flags: Precursor;
GN   Name=FAM171A1; Synonyms=C10orf38;
//
ID   F170B_HUMAN             Reviewed;         283 AA.
AC   A6NMN3; Q86WY6; Q8N6K8;
DE   RecName: Full=Putative protein FAM170B;
GN   Name=FAM170B; Synonyms=C10orf73;
//
ID   F1712_HUMAN             Reviewed;         826 AA.
AC   A8MVW0; A8MQB4;
DE   RecName: Full=Protein FAM171A2;
DE   Flags: Precursor;
GN   Name=FAM171A2;
//
ID   F171B_HUMAN             Reviewed;         826 AA.
AC   Q6P995; Q53SK3; Q8N1Y4; Q8N3K1; Q8N970; Q8NB81; Q8TF55; Q8WYR8;
DE   RecName: Full=Protein FAM171B;
DE   Flags: Precursor;
GN   Name=FAM171B; Synonyms=KIAA1946; ORFNames=NPD019;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
//
ID   F172A_HUMAN             Reviewed;         416 AA.
AC   Q8WUF8; B2R7C6; B4DJ14; B4DLG5; Q9H0U8;
DE   RecName: Full=Protein FAM172A;
DE   Flags: Precursor;
GN   Name=FAM172A; Synonyms=C5orf21;
//
ID   F172B_HUMAN             Reviewed;         362 AA.
AC   A6NC97;
DE   RecName: Full=Putative protein FAM172B;
DE   AltName: Full=FAM172B pseudogene;
GN   Name=FAM172BP; Synonyms=FAM172B;
//
ID   F173A_HUMAN             Reviewed;         235 AA.
AC   Q9BQD7; A2IDD4;
DE   RecName: Full=Protein FAM173A;
GN   Name=FAM173A; Synonyms=C16orf24; ORFNames=RJD7;
//
ID   F174A_HUMAN             Reviewed;         190 AA.
AC   Q8TBP5; A8K0H4;
DE   RecName: Full=Membrane protein FAM174A;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 6;
DE            Short=HCV NS5A-transactivated protein 6;
DE   AltName: Full=Transmembrane protein 157;
DE   Flags: Precursor;
GN   Name=FAM174A; Synonyms=NS5ATP6, TMEM157; ORFNames=UNQ1912/PRO4371;
//
ID   F173B_HUMAN             Reviewed;         233 AA.
AC   Q6P4H8; B4DT41; B4DXK2; E9PBZ4;
DE   RecName: Full=Protein FAM173B;
GN   Name=FAM173B;
//
ID   F174B_HUMAN             Reviewed;         159 AA.
AC   Q3ZCQ3; Q3ZCR9; Q8NBH7;
DE   RecName: Full=Membrane protein FAM174B;
DE   Flags: Precursor;
GN   Name=FAM174B;
//
ID   F175A_HUMAN             Reviewed;         409 AA.
AC   Q6UWZ7; A5JJ07; Q9H8I1; Q9H9N4;
DE   RecName: Full=BRCA1-A complex subunit Abraxas;
DE   AltName: Full=Coiled-coil domain-containing protein 98;
DE   AltName: Full=Protein FAM175A;
GN   Name=FAM175A; Synonyms=ABRA1, CCDC98; ORFNames=UNQ496/PRO1013;
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
//
ID   F175B_HUMAN             Reviewed;         415 AA.
AC   Q15018; B4DKR2; Q96H11;
DE   RecName: Full=BRISC complex subunit Abro1;
DE   AltName: Full=Abraxas brother protein 1;
DE   AltName: Full=Protein FAM175B;
GN   Name=FAM175B; Synonyms=ABRO1, KIAA0157;
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
//
ID   F177A_HUMAN             Reviewed;         213 AA.
AC   Q8N128; Q68CT2;
DE   RecName: Full=Protein FAM177A1;
GN   Name=FAM177A1; Synonyms=C14orf24;
//
ID   F177B_HUMAN             Reviewed;         158 AA.
AC   A6PVY3; Q6ZUN8;
DE   RecName: Full=Protein FAM177B;
GN   Name=FAM177B;
//
ID   F178B_HUMAN             Reviewed;         827 AA.
AC   Q8IXR5; A8MXN2; E9PD86; Q8IUY0; Q9P0P4;
DE   RecName: Full=Protein FAM178B;
GN   Name=FAM178B; ORFNames=HSPC234;
//
ID   F179A_HUMAN             Reviewed;        1019 AA.
AC   Q6ZUX3; Q6ZUF5;
DE   RecName: Full=Protein FAM179A;
GN   Name=FAM179A;
//
ID   F179B_HUMAN             Reviewed;        1720 AA.
AC   Q9Y4F4; Q68D66; Q6PG27;
DE   RecName: Full=Protein FAM179B;
GN   Name=FAM179B; Synonyms=KIAA0423;
//
ID   F178A_HUMAN             Reviewed;        1173 AA.
AC   Q8IX21; A8K950; B1AL17; Q5W0L8; Q6GMU6; Q9NPE8;
DE   RecName: Full=Protein FAM178A;
GN   Name=FAM178A; Synonyms=C10orf6;
//
ID   F180A_HUMAN             Reviewed;         173 AA.
AC   Q6UWF9; B2RP85;
DE   RecName: Full=Protein FAM180A;
DE   Flags: Precursor;
GN   Name=FAM180A; ORFNames=UNQ1940/PRO4423;
//
ID   F180B_HUMAN             Reviewed;         224 AA.
AC   Q6P0A1;
DE   RecName: Full=Protein FAM180B;
GN   Name=FAM180B;
//
ID   F181A_HUMAN             Reviewed;         354 AA.
AC   Q8N9Y4; B2RD39; Q96GY1;
DE   RecName: Full=Protein FAM181A;
GN   Name=FAM181A; Synonyms=C14orf152; ORFNames=HSD-31, HSD31;
//
ID   F181B_HUMAN             Reviewed;         426 AA.
AC   A6NEQ2; B2RWP1;
DE   RecName: Full=Protein FAM181B;
GN   Name=FAM181B;
//
ID   F182A_HUMAN             Reviewed;         154 AA.
AC   Q5T1J6; A2RRD0; Q8N947;
DE   RecName: Full=Protein FAM182A;
GN   Name=FAM182A; Synonyms=C20orf91;
//
ID   F182B_HUMAN             Reviewed;         152 AA.
AC   Q5T319; Q4G0Q1;
DE   RecName: Full=Protein FAM182B;
GN   Name=FAM182B;
//
ID   F183A_HUMAN             Reviewed;         134 AA.
AC   A6NL82; B7ZBL8;
DE   RecName: Full=Protein FAM183A;
GN   Name=FAM183A;
//
ID   F183B_HUMAN             Reviewed;         135 AA.
AC   Q6ZVS7; A4D1Y1;
DE   RecName: Full=Protein FAM183B;
GN   Name=FAM183B;
//
ID   F184A_HUMAN             Reviewed;        1140 AA.
AC   Q8NB25; B9DI75; F8W8D6; Q5TBS9; Q7Z323; Q96GY8; Q9H0J8; Q9H851;
DE   RecName: Full=Protein FAM184A;
GN   Name=FAM184A; Synonyms=C6orf60;
//
ID   F184B_HUMAN             Reviewed;        1060 AA.
AC   Q9ULE4;
DE   RecName: Full=Protein FAM184B;
GN   Name=FAM184B; Synonyms=KIAA1276;
//
ID   F186A_HUMAN             Reviewed;        2351 AA.
AC   A6NE01;
DE   RecName: Full=Protein FAM186A;
GN   Name=FAM186A;
//
ID   F186B_HUMAN             Reviewed;         893 AA.
AC   Q8IYM0; Q8TCP7; Q9H0L3;
DE   RecName: Full=Protein FAM186B;
GN   Name=FAM186B; Synonyms=C12orf25;
//
ID   F187A_HUMAN             Reviewed;         413 AA.
AC   A6NFU0;
DE   RecName: Full=Ig-like V-type domain-containing protein FAM187A;
DE   Flags: Precursor;
GN   Name=FAM187A;
//
ID   F185A_HUMAN             Reviewed;         392 AA.
AC   Q8N0U4; A8MUR7; B4DQD3; C9IZ91;
DE   RecName: Full=Protein FAM185A;
GN   Name=FAM185A;
//
ID   F187B_HUMAN             Reviewed;         369 AA.
AC   Q17R55; Q8N7G6;
DE   RecName: Full=Protein FAM187B;
DE   AltName: Full=Transmembrane protein 162;
DE   Flags: Precursor;
GN   Name=FAM187B; Synonyms=TMEM162;
//
ID   F1882_HUMAN             Reviewed;         360 AA.
AC   A8MYZ0;
DE   RecName: Full=Protein FAM188B2;
GN   Name=FAM188B2; Synonyms=C3orf76;
//
ID   F188A_HUMAN             Reviewed;         445 AA.
AC   Q9H8M7; Q5SZ68; Q5SZ69; Q5SZ70; Q6IA40; Q6P7P0; Q7Z2S1; Q8WUF1;
AC   Q9H3I4;
DE   RecName: Full=Protein FAM188A;
DE   AltName: Full=Dermal papilla-derived protein 5;
DE   AltName: Full=Protein CARP;
GN   Name=FAM188A; Synonyms=C10orf97, CARP, DERP5; ORFNames=MSTP126, My042;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   F188B_HUMAN             Reviewed;         757 AA.
AC   Q4G0A6; Q71AZ7; Q9H6D2;
DE   RecName: Full=Protein FAM188B;
GN   Name=FAM188B; Synonyms=C7orf67;
//
ID   F1891_HUMAN             Reviewed;         539 AA.
AC   O60320; A0PK09;
DE   RecName: Full=Protein FAM189A1;
DE   AltName: Full=Transmembrane protein 228;
GN   Name=FAM189A1; Synonyms=KIAA0574, TMEM228;
//
ID   F189B_HUMAN             Reviewed;         668 AA.
AC   P81408; B1AVS5; Q8IXL3; Q9BR66;
DE   RecName: Full=Protein FAM189B;
DE   AltName: Full=Protein COTE1;
GN   Name=FAM189B; Synonyms=C1orf2, COTE1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
//
ID   F1892_HUMAN             Reviewed;         450 AA.
AC   Q15884; Q14CN5; Q5T6C8; Q5T6C9; Q6ZTX4; Q96N10;
DE   RecName: Full=Protein FAM189A2;
DE   AltName: Full=Protein X123;
DE   Flags: Precursor;
GN   Name=FAM189A2; Synonyms=C9orf61, X123;
//
ID   F193A_HUMAN             Reviewed;        1265 AA.
AC   P78312; B7ZM85; B9EGR0; E9PFA1; O43607; P78311; P78313; Q9UEG8;
DE   RecName: Full=Protein FAM193A;
DE   AltName: Full=Protein IT14;
GN   Name=FAM193A; Synonyms=C4orf8; ORFNames=RES4-22;
//
ID   F193B_HUMAN             Reviewed;         902 AA.
AC   Q96PV7; E9PET5; Q9NW00;
DE   RecName: Full=Protein FAM193B;
GN   Name=FAM193B; Synonyms=KIAA1931;
//
ID   F195A_HUMAN             Reviewed;         160 AA.
AC   Q9BUT9; Q969E9; Q96KV8;
DE   RecName: Full=Protein FAM195A;
GN   Name=FAM195A; Synonyms=C16orf14;
//
ID   F192A_HUMAN             Reviewed;         254 AA.
AC   Q9GZU8;
DE   RecName: Full=Protein FAM192A;
DE   AltName: Full=NEFA-interacting nuclear protein NIP30;
GN   Name=FAM192A; Synonyms=C16orf94, NIP30; ORFNames=CDA018, CDA10;
//
ID   F195B_HUMAN             Reviewed;          97 AA.
AC   C9JLW8; Q6ZUL0;
DE   RecName: Full=Protein FAM195B;
GN   Name=FAM195B;
//
ID   F196A_HUMAN             Reviewed;         479 AA.
AC   Q6ZSG2; B2RNT4;
DE   RecName: Full=Protein FAM196A;
GN   Name=FAM196A; Synonyms=C10orf141;
//
ID   F196B_HUMAN             Reviewed;         535 AA.
AC   A6NMK8;
DE   RecName: Full=Protein FAM196B;
GN   Name=FAM196B; Synonyms=C5orf57;
//
ID   F198A_HUMAN             Reviewed;         575 AA.
AC   Q9UFP1; B3KR48;
DE   RecName: Full=Protein FAM198A;
DE   Flags: Precursor;
GN   Name=FAM198A; Synonyms=C3orf41;
//
ID   F19A1_HUMAN             Reviewed;         133 AA.
AC   Q7Z5A9; A8K0V3; Q8TCL8;
DE   RecName: Full=Protein FAM19A1;
DE   AltName: Full=Chemokine-like protein TAFA-1;
DE   Flags: Precursor;
GN   Name=FAM19A1; Synonyms=TAFA1;
//
ID   F198B_HUMAN             Reviewed;         519 AA.
AC   Q6UWH4; Q498Z3; Q6IAF9; Q6ZMF2; Q86XL0;
DE   RecName: Full=Protein FAM198B;
DE   AltName: Full=Expressed in nerve and epithelium during development;
GN   Name=FAM198B; Synonyms=C4orf18, ENED; ORFNames=AD021, UNQ2512/PRO6001;
//
ID   F19A2_HUMAN             Reviewed;         131 AA.
AC   Q8N3H0; B3KVV4; Q4G0R9; Q68DK0; Q6GTX6;
DE   RecName: Full=Protein FAM19A2;
DE   AltName: Full=Chemokine-like protein TAFA-2;
DE   Flags: Precursor;
GN   Name=FAM19A2; Synonyms=TAFA2;
//
ID   F199X_HUMAN             Reviewed;         388 AA.
AC   Q6PEV8; Q8WVP6; Q96AV3;
DE   RecName: Full=Protein FAM199X;
GN   Name=FAM199X; Synonyms=CXorf39;
//
ID   F19A3_HUMAN             Reviewed;         133 AA.
AC   Q7Z5A8; B7ZLU0; Q2M1P9; Q7Z5A6;
DE   RecName: Full=Protein FAM19A3;
DE   AltName: Full=Chemokine-like protein TAFA-3;
DE   Flags: Precursor;
GN   Name=FAM19A3; Synonyms=TAFA3;
//
ID   F19A5_HUMAN             Reviewed;         132 AA.
AC   Q7Z5A7; A6NII9; B0QZ13; B0QZ14; B0QZ15; O95902; Q5H9C4; Q6UWC9;
AC   Q8IXR8;
DE   RecName: Full=Protein FAM19A5;
DE   AltName: Full=Chemokine-like protein TAFA-5;
GN   Name=FAM19A5; Synonyms=TAFA5; ORFNames=UNQ5208/PRO34524;
//
ID   F19A4_HUMAN             Reviewed;         140 AA.
AC   Q96LR4; A8MVT2;
DE   RecName: Full=Protein FAM19A4;
DE   AltName: Full=Chemokine-like protein TAFA-4;
DE   Flags: Precursor;
GN   Name=FAM19A4; Synonyms=TAFA4;
//
ID   F200B_HUMAN             Reviewed;         657 AA.
AC   P0CF97;
DE   RecName: Full=Putative protein FAM200B;
GN   Name=FAM200B;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   F200A_HUMAN             Reviewed;         573 AA.
AC   Q8TCP9; A4D293; A8K3V9; B2RD92; C9J6A8; D6W5T2; Q8N9P3;
DE   RecName: Full=Protein FAM200A;
GN   Name=FAM200A; Synonyms=C7orf38;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   F203A_HUMAN             Reviewed;         390 AA.
AC   Q9BTY7;
DE   RecName: Full=Protein FAM203A;
DE   AltName: Full=Brain protein 16;
GN   Name=FAM203A; Synonyms=BRP16, C8orf30A;
//
ID   F203B_HUMAN             Reviewed;         390 AA.
AC   P0CB43;
DE   RecName: Full=Protein FAM203B;
DE   AltName: Full=Brain protein 16-like;
GN   Name=FAM203B; Synonyms=BRP16L, C8orf30B;
//
ID   F205A_HUMAN             Reviewed;        1335 AA.
AC   Q6ZU69; A8MVW7;
DE   RecName: Full=Protein FAM205A;
GN   Name=FAM205A; Synonyms=C9orf144B;
//
ID   F201A_HUMAN             Reviewed;         155 AA.
AC   Q5SY85;
DE   RecName: Full=Protein FAM201A;
GN   Name=FAM201A; Synonyms=C9orf122;
//
ID   F205C_HUMAN             Reviewed;         338 AA.
AC   A6NFA0;
DE   RecName: Full=Putative family with sequence similarity 205, member C protein;
GN   Name=FAM205CP;
//
ID   F205B_HUMAN             Reviewed;         556 AA.
AC   Q63HN1; Q6ZRJ7;
DE   RecName: Full=Protein FAM205B;
GN   Name=FAM205B; Synonyms=C9orf144, C9orf144A;
//
ID   F204A_HUMAN             Reviewed;         233 AA.
AC   Q9H8W3; D3DRC6; Q5T373; Q9H5V5;
DE   RecName: Full=Protein FAM204A;
GN   Name=FAM204A; Synonyms=C10orf84;
//
ID   F206A_HUMAN             Reviewed;         181 AA.
AC   Q9NX38; Q5JTR0; Q5JTR1;
DE   RecName: Full=Protein Simiate;
DE   AltName: Full=Protein FAM206A;
GN   Name=FAM206A; Synonyms=C9orf6;
DR   GO; GO:0006546; P:glycine catabolic process; IEA:InterPro.
//
ID   F208A_HUMAN             Reviewed;        1670 AA.
AC   Q9UK61; A1L3A4; B5ME28; Q9H2F7; Q9UPP7;
DE   RecName: Full=Protein FAM208A;
DE   AltName: Full=CTCL tumor antigen se89-1;
DE   AltName: Full=Retinoblastoma-associated protein RAP140;
GN   Name=FAM208A; Synonyms=C3orf63, KIAA1105;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   F207A_HUMAN             Reviewed;         230 AA.
AC   Q9NSI2;
DE   RecName: Full=Protein FAM207A;
GN   Name=FAM207A; Synonyms=C21orf70; ORFNames=PRED56;
//
ID   F208B_HUMAN             Reviewed;        2430 AA.
AC   Q5VWN6; Q2YD91; Q5VWN5; Q6ZRQ8; Q8IVG4; Q9BUZ7; Q9H5J9; Q9H7A4;
AC   Q9H996; Q9NXA1;
DE   RecName: Full=Protein FAM208B;
GN   Name=FAM208B; Synonyms=C10orf18, KIAA2006;
//
ID   F209A_HUMAN             Reviewed;         171 AA.
AC   Q5JX71; Q05C43;
DE   RecName: Full=Protein FAM209A;
DE   Flags: Precursor;
GN   Name=FAM209A; Synonyms=C20orf106;
//
ID   F210A_HUMAN             Reviewed;         272 AA.
AC   Q96ND0; D3DUJ4;
DE   RecName: Full=Protein FAM210A;
GN   Name=FAM210A; Synonyms=C18orf19;
//
ID   F209B_HUMAN             Reviewed;         171 AA.
AC   Q5JX69; Q3KRB5;
DE   RecName: Full=Protein FAM209B;
DE   Flags: Precursor;
GN   Name=FAM209B; Synonyms=C20orf107;
//
ID   F210B_HUMAN             Reviewed;         192 AA.
AC   Q96KR6; B2RBQ9; E1P5Y7; Q8WVN2; Q9BYL6; Q9H418;
DE   RecName: Full=Protein FAM210B;
GN   Name=FAM210B; Synonyms=C20orf108; ORFNames=PSEC0265;
//
ID   F212B_HUMAN             Reviewed;         297 AA.
AC   Q9NTI7; B3KP38; B4DF94; Q9NTI6;
DE   RecName: Full=Protein FAM212B;
GN   Name=FAM212B; Synonyms=C1orf183;
//
ID   F212A_HUMAN             Reviewed;         285 AA.
AC   Q96EL1;
DE   RecName: Full=Protein FAM212A;
GN   Name=FAM212A; Synonyms=C3orf54;
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
//
ID   F213A_HUMAN             Reviewed;         229 AA.
AC   Q9BRX8; B2RD81; Q6UW08; Q8N2K3; Q8NBK9; Q96JR0;
DE   RecName: Full=Redox-regulatory protein FAM213A;
DE   AltName: Full=Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes;
DE            Short=Protein PAMM;
GN   Name=FAM213A; Synonyms=C10orf58, PAMM;
GN   ORFNames=PRO2290, PSEC0139, UNQ611/PRO1198;
DR   GO; GO:0016209; F:antioxidant activity; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IDA:UniProtKB.
//
ID   F214A_HUMAN             Reviewed;        1076 AA.
AC   Q32MH5; A8KA52; B4DEP5; B4DF40; F5H8G0; Q32MH6; Q4G0R7; Q5XJ16;
AC   Q6PDA3; Q9NV24; Q9P2H7;
DE   RecName: Full=Protein FAM214A;
GN   Name=FAM214A; Synonyms=KIAA1370;
//
ID   F214B_HUMAN             Reviewed;         538 AA.
AC   Q7L5A3; B1AML4; B1AML5; D3DRN5; O60377; Q9BQ60; Q9HAI9; Q9P1Y9;
DE   RecName: Full=Protein FAM214B;
GN   Name=FAM214B; Synonyms=KIAA1539;
//
ID   F215A_HUMAN             Reviewed;         114 AA.
AC   Q9Y5M1; Q6NTD6;
DE   RecName: Full=Putative protein FAM215A;
DE   AltName: Full=Putative apoptosis-related protein 2;
DE            Short=APR-2;
GN   Name=FAM215A; Synonyms=APR2, C17orf88;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   F216A_HUMAN             Reviewed;         273 AA.
AC   Q8WUB2; A6NH30; Q99776;
DE   RecName: Full=Protein FAM216A;
GN   Name=FAM216A; Synonyms=C12orf24;
//
ID   F217A_HUMAN             Reviewed;         508 AA.
AC   Q8IXS0; Q5JYK1;
DE   RecName: Full=Protein FAM217A;
GN   Name=FAM217A; Synonyms=C6orf146;
//
ID   F216B_HUMAN             Reviewed;         139 AA.
AC   Q8N7L0; B1ALI3;
DE   RecName: Full=Protein FAM216B;
GN   Name=FAM216B; Synonyms=C13orf30;
//
ID   F217B_HUMAN             Reviewed;         383 AA.
AC   Q9NTX9; B3KWH1; Q9NTA3;
DE   RecName: Full=Protein FAM217B;
GN   Name=FAM217B; Synonyms=C20orf177;
//
ID   F218A_HUMAN             Reviewed;         157 AA.
AC   Q96MZ4;
DE   RecName: Full=Protein FAM218A;
GN   Name=FAM218A; Synonyms=C4orf39;
//
ID   F219A_HUMAN             Reviewed;         185 AA.
AC   Q8IW50; A2A364; B4DFE1; B4DSR8; Q5T590; Q5T591; Q5T592; Q5T594;
AC   Q5T595; Q8TAZ8;
DE   RecName: Full=Protein FAM219A;
GN   Name=FAM219A; Synonyms=C9orf25;
//
ID   F220A_HUMAN             Reviewed;         259 AA.
AC   Q7Z4H9; Q75ML2; Q8NA52; Q9BRR7;
DE   RecName: Full=Protein FAM220A;
DE   AltName: Full=STAT3-interacting protein as a repressor;
GN   Name=FAM220A; Synonyms=C7orf70, SIPAR;
//
ID   F219B_HUMAN             Reviewed;         198 AA.
AC   Q5XKK7; A8K4Q5; B4DK57; Q9NXY0;
DE   RecName: Full=Protein FAM219B;
GN   Name=FAM219B; Synonyms=C15orf17;
//
ID   F220P_HUMAN             Reviewed;         271 AA.
AC   B1ANY3;
DE   RecName: Full=Putative protein FAM220BP;
DE   AltName: Full=Protein FAM220B pseudogene;
GN   Name=FAM220BP; Synonyms=C9orf51;
//
ID   F221A_HUMAN             Reviewed;         298 AA.
AC   A4D161; Q05CG4; Q4G0Q7; Q6P519;
DE   RecName: Full=Protein FAM221A;
GN   Name=FAM221A; Synonyms=C7orf46;
//
ID   F222A_HUMAN             Reviewed;         452 AA.
AC   Q5U5X8; Q8NCD5; Q96SP6;
DE   RecName: Full=Protein FAM222A;
GN   Name=FAM222A; Synonyms=C12orf34;
//
ID   F222B_HUMAN             Reviewed;         562 AA.
AC   Q8WU58; Q9H6F3; Q9NVJ4; Q9NXN6;
DE   RecName: Full=Protein FAM222B;
GN   Name=FAM222B; Synonyms=C17orf63;
//
ID   F221B_HUMAN             Reviewed;         402 AA.
AC   A6H8Z2; Q5TCW2;
DE   RecName: Full=Protein FAM221B;
GN   Name=FAM221B; Synonyms=C9orf128;
//
ID   F223B_HUMAN             Reviewed;         122 AA.
AC   A6NKX1;
DE   RecName: Full=Protein FAM223B;
GN   Name=FAM223B; Synonyms=CXorf52B, LINC00204B;
//
ID   F227A_HUMAN             Reviewed;         570 AA.
AC   F5H4B4; B0QY52; B7Z7C6; Q5TG08;
DE   RecName: Full=Protein FAM227A;
GN   Name=FAM227A;
//
ID   F227B_HUMAN             Reviewed;         508 AA.
AC   Q96M60; Q86WS2;
DE   RecName: Full=Protein FAM227B;
GN   Name=FAM227B; Synonyms=C15orf33;
//
ID   F222C_HUMAN             Reviewed;         195 AA.
AC   Q6P4D5; F5H036; Q8WVK9;
DE   RecName: Full=Protein FAM122C;
GN   Name=FAM122C;
//
ID   F223A_HUMAN             Reviewed;         122 AA.
AC   Q8IWN6;
DE   RecName: Full=Protein FAM223A;
DE   AltName: Full=SPCX;
GN   Name=FAM223A; Synonyms=CXorf52, LINC00204A, NCRNA00204;
//
ID   F228A_HUMAN             Reviewed;         206 AA.
AC   Q86W67;
DE   RecName: Full=Protein FAM228A;
GN   Name=FAM228A; Synonyms=C2orf84;
//
ID   F228B_HUMAN             Reviewed;         321 AA.
AC   P0C875;
DE   RecName: Full=Protein FAM228B;
GN   Name=FAM228B;
//
ID   F229A_HUMAN             Reviewed;         127 AA.
AC   H3BQW9;
DE   RecName: Full=Protein FAM229A;
GN   Name=FAM229A;
//
ID   F231D_HUMAN             Reviewed;         169 AA.
AC   Q6ZW35; I3L0A6;
DE   RecName: Full=Protein FAM231D;
GN   Name=FAM231D;
//
ID   F231A_HUMAN             Reviewed;         169 AA.
AC   A6NEA5;
DE   RecName: Full=Protein FAM231A/C;
GN   Name=FAM231A;
GN   and
GN   Name=FAM231C;
//
ID   F231B_HUMAN             Reviewed;         169 AA.
AC   A6NCW3;
DE   RecName: Full=Protein FAM231B;
GN   Name=FAM231B;
//
ID   F229B_HUMAN             Reviewed;          80 AA.
AC   Q4G0N7; B8ZZ33;
DE   RecName: Full=Protein FAM229B;
GN   Name=FAM229B; Synonyms=C6orf225;
//
ID   F261_HUMAN              Reviewed;         471 AA.
AC   P16118; B2RA88; B4DUN5; Q5JXS5; Q99951;
DE   RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1;
DE            Short=6PF-2-K/Fru-2,6-P2ase 1;
DE            Short=PFK/FBPase 1;
DE   AltName: Full=6PF-2-K/Fru-2,6-P2ase liver isozyme;
DE   Includes:
DE     RecName: Full=6-phosphofructo-2-kinase;
DE              EC=2.7.1.105;
DE   Includes:
DE     RecName: Full=Fructose-2,6-bisphosphatase;
DE              EC=3.1.3.46;
GN   Name=PFKFB1; Synonyms=F6PK, PFRX;
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:InterPro.
DR   GO; GO:0070095; F:fructose-6-phosphate binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0033133; P:positive regulation of glucokinase activity; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   F25DE_HUMAN             Reviewed;         175 AA.
AC   A8MYX2;
DE   RecName: Full=Protein FAM25D/E;
GN   Name=FAM25D;
GN   and
GN   Name=FAM25E;
//
ID   F262_HUMAN              Reviewed;         505 AA.
AC   O60825; O60824; Q5VVQ3; Q5VVQ4; Q9H3P1;
DE   RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2;
DE            Short=6PF-2-K/Fru-2,6-P2ase 2;
DE            Short=PFK/FBPase 2;
DE   AltName: Full=6PF-2-K/Fru-2,6-P2ase heart-type isozyme;
DE   Includes:
DE     RecName: Full=6-phosphofructo-2-kinase;
DE              EC=2.7.1.105;
DE   Includes:
DE     RecName: Full=Fructose-2,6-bisphosphatase;
DE              EC=3.1.3.46;
GN   Name=PFKFB2;
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:GOC.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006000; P:fructose metabolic process; TAS:ProtInc.
DR   GO; GO:0006007; P:glucose catabolic process; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IDA:UniProtKB.
DR   GO; GO:0006089; P:lactate metabolic process; IEA:Ensembl.
DR   GO; GO:0033133; P:positive regulation of glucokinase activity; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   F263_HUMAN              Reviewed;         520 AA.
AC   Q16875; B7Z955; O43622; O75902; Q5VX15; Q5VX18; Q5VX19;
DE   RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;
DE            Short=6PF-2-K/Fru-2,6-P2ase 3;
DE            Short=PFK/FBPase 3;
DE   AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;
DE   AltName: Full=Renal carcinoma antigen NY-REN-56;
DE   AltName: Full=iPFK-2;
DE   Includes:
DE     RecName: Full=6-phosphofructo-2-kinase;
DE              EC=2.7.1.105;
DE   Includes:
DE     RecName: Full=Fructose-2,6-bisphosphatase;
DE              EC=3.1.3.46;
GN   Name=PFKFB3;
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; NAS:GOC.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   F264_HUMAN              Reviewed;         469 AA.
AC   Q16877; Q5S3G5;
DE   RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4;
DE            Short=6PF-2-K/Fru-2,6-P2ase 4;
DE            Short=PFK/FBPase 4;
DE   AltName: Full=6PF-2-K/Fru-2,6-P2ase testis-type isozyme;
DE   Includes:
DE     RecName: Full=6-phosphofructo-2-kinase;
DE              EC=2.7.1.105;
DE   Includes:
DE     RecName: Full=Fructose-2,6-bisphosphatase;
DE              EC=3.1.3.46;
GN   Name=PFKFB4;
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; NAS:GOC.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   F27D1_HUMAN             Reviewed;         215 AA.
AC   Q5T7N8; Q5VSL6;
DE   RecName: Full=Protein FAM27D1;
GN   Name=FAM27D1;
//
ID   F27E2_HUMAN             Reviewed;         125 AA.
AC   Q5SNX5; A8E4L5;
DE   RecName: Full=Protein FAM27E2;
GN   Name=FAM27E2;
//
ID   F27E3_HUMAN             Reviewed;         113 AA.
AC   Q08E93;
DE   RecName: Full=Protein FAM27E3;
GN   Name=FAM27E3;
//
ID   F27E1_HUMAN             Reviewed;         126 AA.
AC   Q5T7N7;
DE   RecName: Full=Putative protein FAM27E1;
GN   Name=FAM27E1;
//
ID   F71E1_HUMAN             Reviewed;         247 AA.
AC   Q6IPT2; Q96EJ5; Q9BSM9;
DE   RecName: Full=Protein FAM71E1;
GN   Name=FAM71E1;
//
ID   F71F1_HUMAN             Reviewed;         344 AA.
AC   Q96KD3; Q8IY75;
DE   RecName: Full=Protein FAM71F1;
DE   AltName: Full=Protein FAM137A;
DE   AltName: Full=Testis development protein NYD-SP18;
GN   Name=FAM71F1; Synonyms=FAM137A;
//
ID   F71E2_HUMAN             Reviewed;         922 AA.
AC   Q8N5Q1; Q8ND99;
DE   RecName: Full=Putative protein FAM71E2;
GN   Name=FAM71E2; Synonyms=C19orf16;
//
ID   F71F2_HUMAN             Reviewed;         309 AA.
AC   Q6NXP2; Q0VGF6; Q0VGF7; Q86X39;
DE   RecName: Full=Protein FAM71F2;
DE   AltName: Full=Protein FAM137B;
GN   Name=FAM71F2; Synonyms=FAM137B;
//
ID   F74A1_HUMAN             Reviewed;         127 AA.
AC   Q5RGS3; A6NK17;
DE   RecName: Full=Protein FAM74A1/A2;
GN   Name=FAM74A1;
GN   and
GN   Name=FAM74A2;
//
ID   F74A7_HUMAN             Reviewed;         159 AA.
AC   A6NL05;
DE   RecName: Full=Protein FAM74A7;
GN   Name=FAM74A7;
//
ID   F74A3_HUMAN             Reviewed;         159 AA.
AC   Q4VXF1;
DE   RecName: Full=Putative protein FAM74A3;
GN   Name=FAM74A3;
//
ID   F86B2_HUMAN             Reviewed;         330 AA.
AC   P0C5J1;
DE   RecName: Full=Protein FAM86B2;
GN   Name=FAM86B2;
//
ID   F86C2_HUMAN             Reviewed;         165 AA.
AC   A6NEL3;
DE   RecName: Full=Putative protein FAM86C2P;
GN   Name=FAM86C2P;
//
ID   F86B1_HUMAN             Reviewed;         296 AA.
AC   Q8N7N1;
DE   RecName: Full=Protein FAM86B1;
GN   Name=FAM86B1;
//
ID   F90A2_HUMAN             Reviewed;         463 AA.
AC   Q658T7;
DE   RecName: Full=Putative protein FAM90A2P;
GN   Name=FAM90A2P;
//
ID   F8I2_HUMAN              Reviewed;         371 AA.
AC   P23610; Q5HY66; Q8IXP3;
DE   RecName: Full=Factor VIII intron 22 protein;
DE   AltName: Full=CpG island protein;
GN   Name=F8A1; Synonyms=F8A;
GN   and
GN   Name=F8A2; Synonyms=F8A;
GN   and
GN   Name=F8A3; Synonyms=F8A;
//
ID   F90A8_HUMAN             Reviewed;         464 AA.
AC   A6NJQ4;
DE   RecName: Full=Putative protein FAM90A8P;
GN   Name=FAM90A8P; Synonyms=FAM90A8;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AA_HUMAN             Reviewed;         464 AA.
AC   A6NDY2;
DE   RecName: Full=Putative protein FAM90A10P;
GN   Name=FAM90A10P; Synonyms=FAM90A10;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90A1_HUMAN             Reviewed;         464 AA.
AC   Q86YD7; D3DUU9; Q9NVZ6;
DE   RecName: Full=Protein FAM90A1;
GN   Name=FAM90A1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90A5_HUMAN             Reviewed;         464 AA.
AC   A8MXJ8;
DE   RecName: Full=Putative protein FAM90A5P;
GN   Name=FAM90A5P; Synonyms=FAM90A5;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AD_HUMAN             Reviewed;         464 AA.
AC   P0C7W8;
DE   RecName: Full=Putative protein FAM90A13P;
GN   Name=FAM90A13P; Synonyms=FAM90A13;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AC_HUMAN             Reviewed;         464 AA.
AC   A8MX19;
DE   RecName: Full=Putative protein FAM90A12P;
GN   Name=FAM90A12P; Synonyms=FAM90A12;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AE_HUMAN             Reviewed;         464 AA.
AC   P0C7W9;
DE   RecName: Full=Putative protein FAM90A14P;
GN   Name=FAM90A14P; Synonyms=FAM90A14;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AJ_HUMAN             Reviewed;         464 AA.
AC   P0C7V4;
DE   RecName: Full=Putative protein FAM90A15P;
GN   Name=FAM90A15P; Synonyms=FAM90A15;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AK_HUMAN             Reviewed;         464 AA.
AC   A6NIJ5;
DE   RecName: Full=Putative protein FAM90A20P;
GN   Name=FAM90A20P; Synonyms=FAM90A20;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90A7_HUMAN             Reviewed;         464 AA.
AC   A6NKC0;
DE   RecName: Full=Putative protein FAM90A7P;
GN   Name=FAM90A7P; Synonyms=FAM90A7;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AG_HUMAN             Reviewed;         464 AA.
AC   A6NEW6;
DE   RecName: Full=Putative protein FAM90A16P/FAM90A17P;
GN   Name=FAM90A16P; Synonyms=FAM90A16;
GN   and
GN   Name=FAM90A17P; Synonyms=FAM90A17;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AM_HUMAN             Reviewed;         464 AA.
AC   A8MWA6;
DE   RecName: Full=Putative protein FAM90A22P;
GN   Name=FAM90A22P; Synonyms=FAM90A22;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AR_HUMAN             Reviewed;         459 AA.
AC   A6NNH2;
DE   RecName: Full=Protein FAM90A27P;
GN   Name=FAM90A27P;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F91A1_HUMAN             Reviewed;         838 AA.
AC   Q658Y4; B6YY23; Q658T5; Q8TE89;
DE   RecName: Full=Protein FAM91A1;
GN   Name=FAM91A1;
//
ID   F90AO_HUMAN             Reviewed;         464 AA.
AC   P0C7X0; A8MWA1;
DE   RecName: Full=Putative protein FAM90A24P;
GN   Name=FAM90A24P; Synonyms=FAM90A24;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F91A2_HUMAN             Reviewed;         280 AA.
AC   P0C866;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00869;
GN   Name=LINC00869; Synonyms=FAM91A2, KIAA0493;
//
ID   F90AI_HUMAN             Reviewed;         464 AA.
AC   A6NE21;
DE   RecName: Full=Putative protein FAM90A18P/FAM90A19P;
GN   Name=FAM90A18P; Synonyms=FAM90A18;
GN   and
GN   Name=FAM90A19P; Synonyms=FAM90A19;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F90AN_HUMAN             Reviewed;         464 AA.
AC   A8MXZ1;
DE   RecName: Full=Putative protein FAM90A23P;
GN   Name=FAM90A23P; Synonyms=FAM90A23;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   F92A1_HUMAN             Reviewed;         289 AA.
AC   A1XBS5; A1XBS4; Q32ND3; Q6AHW7; Q8N8R1; Q96L09;
DE   RecName: Full=Protein FAM92A1;
GN   Name=FAM92A1;
//
ID   F90A9_HUMAN             Reviewed;         464 AA.
AC   A6NNJ1;
DE   RecName: Full=Putative protein FAM90A9P;
GN   Name=FAM90A9P; Synonyms=FAM90A9;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   FA10_HUMAN              Reviewed;         488 AA.
AC   P00742; Q14340;
DE   RecName: Full=Coagulation factor X;
DE            EC=3.4.21.6;
DE   AltName: Full=Stuart factor;
DE   AltName: Full=Stuart-Prower factor;
DE   Contains:
DE     RecName: Full=Factor X light chain;
DE   Contains:
DE     RecName: Full=Factor X heavy chain;
DE   Contains:
DE     RecName: Full=Activated factor Xa heavy chain;
DE   Flags: Precursor;
GN   Name=F10;
DR   GuidetoPHARMACOLOGY; 2359; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; IC:BHF-UCL.
DR   GO; GO:0007598; P:blood coagulation, extrinsic pathway; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; TAS:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
//
ID   FA11_HUMAN              Reviewed;         625 AA.
AC   P03951; D3DP64; Q4W5C2; Q9Y495;
DE   RecName: Full=Coagulation factor XI;
DE            Short=FXI;
DE            EC=3.4.21.27;
DE   AltName: Full=Plasma thromboplastin antecedent;
DE            Short=PTA;
DE   Contains:
DE     RecName: Full=Coagulation factor XIa heavy chain;
DE   Contains:
DE     RecName: Full=Coagulation factor XIa light chain;
DE   Flags: Precursor;
GN   Name=F11;
DR   GuidetoPHARMACOLOGY; 2360; -.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070009; F:serine-type aminopeptidase activity; IEA:Ensembl.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; NAS:UniProtKB.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0031639; P:plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0051919; P:positive regulation of fibrinolysis; IDA:BHF-UCL.
//
ID   FA12_HUMAN              Reviewed;         615 AA.
AC   P00748; P78339;
DE   RecName: Full=Coagulation factor XII;
DE            EC=3.4.21.38;
DE   AltName: Full=Hageman factor;
DE            Short=HAF;
DE   Contains:
DE     RecName: Full=Coagulation factor XIIa heavy chain;
DE   Contains:
DE     RecName: Full=Beta-factor XIIa part 1;
DE   Contains:
DE     RecName: Full=Beta-factor XIIa part 2;
DE   Contains:
DE     RecName: Full=Coagulation factor XIIa light chain;
DE   Flags: Precursor;
GN   Name=F12;
DR   GuidetoPHARMACOLOGY; 2361; -.
DR   GO; GO:0051787; F:misfolded protein binding; IC:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070009; F:serine-type aminopeptidase activity; IEA:Ensembl.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; IC:BHF-UCL.
DR   GO; GO:0002542; P:Factor XII activation; IDA:BHF-UCL.
DR   GO; GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0002353; P:plasma kallikrein-kinin cascade; IDA:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0051919; P:positive regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0010756; P:positive regulation of plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0016540; P:protein autoprocessing; IDA:BHF-UCL.
DR   GO; GO:0016485; P:protein processing; IDA:BHF-UCL.
DR   GO; GO:0051788; P:response to misfolded protein; IDA:BHF-UCL.
DR   GO; GO:0031638; P:zymogen activation; IDA:BHF-UCL.
//
ID   FA13A_HUMAN             Reviewed;        1023 AA.
AC   O94988; B4DLC1; Q24JP0; Q5PR21; Q8NBA3;
DE   RecName: Full=Protein FAM13A;
GN   Name=FAM13A; Synonyms=FAM13A1, KIAA0914;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   FA13B_HUMAN             Reviewed;         915 AA.
AC   Q9NYF5; D3DQB5; G3V0H9; Q3ZCR0; Q6PGQ2; Q9P0I7;
DE   RecName: Full=Protein FAM13B;
DE   AltName: Full=GAP-like protein N61;
GN   Name=FAM13B; Synonyms=C5orf5, FAM13B1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   FA13C_HUMAN             Reviewed;         585 AA.
AC   Q8NE31; B7ZB77; Q5T631; Q6P2M3; Q99787;
DE   RecName: Full=Protein FAM13C;
GN   Name=FAM13C; Synonyms=FAM13C1;
//
ID   FA156_HUMAN             Reviewed;         213 AA.
AC   Q8NDB6; B3KQ92; Q5JPL2; Q5JPL3; Q5JPL4; Q5JPL5; Q5JPL6; Q68D17;
AC   Q6NVY3; Q9UI49;
DE   RecName: Full=Protein FAM156A/FAM156B;
DE   AltName: Full=Transmembrane protein 29/29B;
GN   Name=FAM156A; Synonyms=TMEM29; ORFNames=PP12994, PRO0659;
GN   and
GN   Name=FAM156B; Synonyms=TMEM29B;
//
ID   FA20A_HUMAN             Reviewed;         541 AA.
AC   Q96MK3; B2RN47; B2RN49; Q9UF95;
DE   RecName: Full=Protein FAM20A;
DE   Flags: Precursor;
GN   Name=FAM20A; ORFNames=UNQ9388/PRO34279;
DR   GO; GO:0070166; P:enamel mineralization; IEA:Ensembl.
//
ID   FA21A_HUMAN             Reviewed;        1341 AA.
AC   Q641Q2; A2A3S2; A2A3U6; Q6DHY0;
DE   RecName: Full=WASH complex subunit FAM21A;
GN   Name=FAM21A;
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   FA21B_HUMAN             Reviewed;        1253 AA.
AC   Q5SNT6;
DE   RecName: Full=WASH complex subunit FAM21B;
GN   Name=FAM21B;
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   FA21D_HUMAN             Reviewed;         308 AA.
AC   Q5SRD0;
DE   RecName: Full=Putative WASH complex subunit FAM21;
GN   Name=FAM21D;
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   FA21C_HUMAN             Reviewed;        1318 AA.
AC   Q9Y4E1; B4DZQ6; B9EK53; F5H0J6; F5H871; Q5SQU4; Q5SQU5; Q7L521;
AC   Q9UG79;
DE   RecName: Full=WASH complex subunit FAM21C;
DE   AltName: Full=Vaccinia virus penetration factor;
DE            Short=VPEF;
GN   Name=FAM21C; Synonyms=KIAA0592;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   FA24B_HUMAN             Reviewed;          94 AA.
AC   Q8N5W8; Q5JPG1;
DE   RecName: Full=Protein FAM24B;
DE   Flags: Precursor;
GN   Name=FAM24B;
//
ID   FA26D_HUMAN             Reviewed;         314 AA.
AC   Q5JW98; B0QZ25; B0QZ27; B4DTQ0; Q96MK0;
DE   RecName: Full=Protein FAM26D;
GN   Name=FAM26D; Synonyms=C6orf78; ORFNames=UNQ6481/PRO21277;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   FA24A_HUMAN             Reviewed;         105 AA.
AC   A6NFZ4;
DE   RecName: Full=Protein FAM24A;
DE   Flags: Precursor;
GN   Name=FAM24A;
//
ID   FA26E_HUMAN             Reviewed;         309 AA.
AC   Q8N5C1; B2RDJ9; B3KSR3;
DE   RecName: Full=Protein FAM26E;
GN   Name=FAM26E; Synonyms=C6orf188;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   FA26F_HUMAN             Reviewed;         315 AA.
AC   Q5R3K3;
DE   RecName: Full=Protein FAM26F;
GN   Name=FAM26F; Synonyms=C6orf187;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   FA27L_HUMAN             Reviewed;          71 AA.
AC   Q8N5T8;
DE   RecName: Full=Protein FAM27L;
GN   Name=FAM27L;
//
ID   FA2H_HUMAN              Reviewed;         372 AA.
AC   Q7L5A8; O75213; Q96DK1; Q9H1A5;
DE   RecName: Full=Fatty acid 2-hydroxylase;
DE            EC=1.-.-.-;
DE   AltName: Full=Fatty acid alpha-hydroxylase;
GN   Name=FA2H; Synonyms=FAAH;
DR   GO; GO:0080132; F:fatty acid alpha-hydroxylase activity; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0032286; P:central nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0030258; P:lipid modification; IEA:Ensembl.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042634; P:regulation of hair cycle; IEA:Ensembl.
DR   GO; GO:0001949; P:sebaceous gland cell differentiation; IEA:Ensembl.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
//
ID   FA32A_HUMAN             Reviewed;         112 AA.
AC   Q9Y421; Q9BT02;
DE   RecName: Full=Protein FAM32A;
DE   AltName: Full=Ovarian tumor-associated gene 12;
DE            Short=OTAG-12;
GN   Name=FAM32A; Synonyms=OTAG12; ORFNames=CGI-144;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   FA35A_HUMAN             Reviewed;         835 AA.
AC   Q86V20; O95885; Q9H991;
DE   RecName: Full=Protein FAM35A;
GN   Name=FAM35A;
//
ID   FA45A_HUMAN             Reviewed;         357 AA.
AC   Q8TCE6; B1AMV6; B4DDC3; D3DRC8; Q9NXW4;
DE   RecName: Full=Protein FAM45A;
GN   Name=FAM45A;
//
ID   FA43A_HUMAN             Reviewed;         423 AA.
AC   Q8N2R8; A3KME2; Q8IXP4; Q8WZ07;
DE   RecName: Full=Protein FAM43A;
GN   Name=FAM43A; ORFNames=PP7298;
//
ID   FA43B_HUMAN             Reviewed;         329 AA.
AC   Q6ZT52; A5PL01;
DE   RecName: Full=Protein FAM43B;
GN   Name=FAM43B;
//
ID   FA45B_HUMAN             Reviewed;         357 AA.
AC   Q6NSW5; Q5H9G7; Q9NZ36;
DE   RecName: Full=Protein FAM45B;
GN   Name=FAM45B; ORFNames=HT011;
//
ID   FA46B_HUMAN             Reviewed;         425 AA.
AC   Q96A09;
DE   RecName: Full=Protein FAM46B;
GN   Name=FAM46B;
//
ID   FA46A_HUMAN             Reviewed;         442 AA.
AC   Q96IP4; A8K7U4; Q5TF86; Q8NFZ9; Q9BW32; Q9NXV5;
DE   RecName: Full=Protein FAM46A;
DE   AltName: Full=HBV X-transactivated gene 11 protein;
DE   AltName: Full=HBV XAg-transactivated protein 11;
GN   Name=FAM46A; Synonyms=C6orf37, XTP11;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   FA46C_HUMAN             Reviewed;         391 AA.
AC   Q5VWP2; A3KMG2; Q8NE25; Q9NXK0;
DE   RecName: Full=Protein FAM46C;
GN   Name=FAM46C;
//
ID   FA46D_HUMAN             Reviewed;         389 AA.
AC   Q8NEK8; B2R9Q6; Q7Z3F6; Q8NHU1;
DE   RecName: Full=Protein FAM46D;
GN   Name=FAM46D;
//
ID   FA47A_HUMAN             Reviewed;         791 AA.
AC   Q5JRC9; A8K8I9; Q8TAA0;
DE   RecName: Full=Protein FAM47A;
GN   Name=FAM47A;
//
ID   FA47C_HUMAN             Reviewed;        1035 AA.
AC   Q5HY64; Q6ZU46;
DE   RecName: Full=Putative protein FAM47C;
GN   Name=FAM47C;
//
ID   FA47D_HUMAN             Reviewed;         397 AA.
AC   A6NHR8;
DE   RecName: Full=Putative protein FAM47D;
GN   Name=FAM47DP;
//
ID   FA47B_HUMAN             Reviewed;         645 AA.
AC   Q8NA70; Q5JQN5; Q6PIG3;
DE   RecName: Full=Protein FAM47B;
GN   Name=FAM47B;
//
ID   FA49A_HUMAN             Reviewed;         323 AA.
AC   Q9H0Q0;
DE   RecName: Full=Protein FAM49A;
GN   Name=FAM49A;
//
ID   FA47E_HUMAN             Reviewed;         393 AA.
AC   Q6ZV65; D6R8Y4;
DE   RecName: Full=Protein FAM47E;
GN   Name=FAM47E;
//
ID   FA49B_HUMAN             Reviewed;         324 AA.
AC   Q9NUQ9; Q96AZ5; Q9NZE7;
DE   RecName: Full=Protein FAM49B;
DE   AltName: Full=L1;
GN   Name=FAM49B; ORFNames=BM-009;
//
ID   FA50A_HUMAN             Reviewed;         339 AA.
AC   Q14320; A8KAQ4; B2R997; Q5HY37;
DE   RecName: Full=Protein FAM50A;
DE   AltName: Full=Protein HXC-26;
DE   AltName: Full=Protein XAP-5;
GN   Name=FAM50A; Synonyms=DXS9928E, HXC26, XAP5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   FA53A_HUMAN             Reviewed;         398 AA.
AC   Q6NSI3; Q6ZUL5;
DE   RecName: Full=Protein FAM53A;
DE   AltName: Full=Dorsal neural-tube nuclear protein;
GN   Name=FAM53A;
//
ID   FA50B_HUMAN             Reviewed;         325 AA.
AC   Q9Y247; Q5T2L6;
DE   RecName: Full=Protein FAM50B;
DE   AltName: Full=Protein XAP-5-like;
GN   Name=FAM50B; Synonyms=X5L;
//
ID   FA53B_HUMAN             Reviewed;         422 AA.
AC   Q14153; D3DRF1; Q5VUW1; Q5VUW2; Q8N5S6;
DE   RecName: Full=Protein FAM53B;
GN   Name=FAM53B; Synonyms=KIAA0140;
//
ID   FA53C_HUMAN             Reviewed;         392 AA.
AC   Q9NYF3; B2RDJ5; D3DQB9;
DE   RecName: Full=Protein FAM53C;
GN   Name=FAM53C; Synonyms=C5orf6;
//
ID   FA57A_HUMAN             Reviewed;         257 AA.
AC   Q8TBR7; A8K7Q0; Q7Z464; Q96D97; Q9H6H3;
DE   RecName: Full=Protein FAM57A;
DE   AltName: Full=Protein CT120;
GN   Name=FAM57A;
//
ID   FA57B_HUMAN             Reviewed;         274 AA.
AC   Q71RH2; Q9H0J1;
DE   RecName: Full=Protein FAM57B;
GN   Name=FAM57B; ORFNames=FP1188;
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
//
ID   FA58A_HUMAN             Reviewed;         248 AA.
AC   Q8N1B3; Q2I380; Q330J9; Q96IU5; Q9BUU1;
DE   RecName: Full=Cyclin-related protein FAM58A;
DE   AltName: Full=Cyclin-M;
GN   Name=FAM58A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   FA58B_HUMAN             Reviewed;         252 AA.
AC   P0C7Q3;
DE   RecName: Full=Putative cyclin-related protein FAM58B;
GN   Name=FAM58BP; Synonyms=FAM58B;
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   FA5_HUMAN               Reviewed;        2224 AA.
AC   P12259; A8K6E8; Q14285; Q2EHR5; Q5R346; Q5R347; Q6UPU6; Q8WWQ6;
DE   RecName: Full=Coagulation factor V;
DE   AltName: Full=Activated protein C cofactor;
DE   AltName: Full=Proaccelerin, labile factor;
DE   Contains:
DE     RecName: Full=Coagulation factor V heavy chain;
DE   Contains:
DE     RecName: Full=Coagulation factor V light chain;
DE   Flags: Precursor;
GN   Name=F5;
DR   GuidetoPHARMACOLOGY; 2606; -.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   FA60A_HUMAN             Reviewed;         221 AA.
AC   Q9NP50; D3DUV8; Q9BSZ8;
DE   RecName: Full=Protein FAM60A;
DE   AltName: Full=Tera protein homolog;
GN   Name=FAM60A; Synonyms=C12orf14; ORFNames=L4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
//
ID   FA63A_HUMAN             Reviewed;         469 AA.
AC   Q8N5J2; B3KWP4; B3KWV8; B4DXF2; B4E1S4; D3DV09; J3KP53; Q5SZF0;
AC   Q9NUL9; Q9P2F7;
DE   RecName: Full=Protein FAM63A;
GN   Name=FAM63A; Synonyms=KIAA1390;
//
ID   FA63B_HUMAN             Reviewed;         621 AA.
AC   Q8NBR6; B2RTT8; Q9ULQ6;
DE   RecName: Full=Protein FAM63B;
GN   Name=FAM63B; Synonyms=KIAA1164;
//
ID   FA64A_HUMAN             Reviewed;         248 AA.
AC   Q9BSJ6; Q96CT4; Q9NVV1; Q9NWB5;
DE   RecName: Full=Protein FAM64A;
DE   AltName: Full=CALM-interactor expressed in thymus and spleen;
DE   AltName: Full=Regulator of chromosome segregation protein 1;
GN   Name=FAM64A; Synonyms=CATS, RCS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   FA65A_HUMAN             Reviewed;        1223 AA.
AC   Q6ZS17; B4DEQ9; B4DIM2; E9PBS3; Q4G0A4; Q7Z5R7; Q8NDA4; Q96J39;
AC   Q96PV8; Q9H8D9;
DE   RecName: Full=Protein FAM65A;
GN   Name=FAM65A; Synonyms=KIAA1930;
//
ID   FA65B_HUMAN             Reviewed;        1068 AA.
AC   Q9Y4F9; A6NHP2; Q13529; Q5VV37; Q5VV38; Q9BQ28;
DE   RecName: Full=Protein FAM65B;
GN   Name=FAM65B; Synonyms=C6orf32, DIFF48, KIAA0386, PL48;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
//
ID   FA65C_HUMAN             Reviewed;         946 AA.
AC   Q96MK2; Q5QPB6; Q9NQQ2;
DE   RecName: Full=Protein FAM65C;
GN   Name=FAM65C; Synonyms=C20orf175;
//
ID   FA66E_HUMAN             Reviewed;          47 AA.
AC   P0C841;
DE   RecName: Full=Putative protein FAM66E;
GN   Name=FAM66E;
//
ID   FA69A_HUMAN             Reviewed;         428 AA.
AC   Q5T7M9; Q6IRV2;
DE   RecName: Full=Protein FAM69A;
GN   Name=FAM69A;
//
ID   FA69B_HUMAN             Reviewed;         431 AA.
AC   Q5VUD6; Q5VUD7; Q8N5N0; Q8WYU5;
DE   RecName: Full=Protein FAM69B;
GN   Name=FAM69B; Synonyms=C9orf136; ORFNames=PP6977;
//
ID   FA69C_HUMAN             Reviewed;         419 AA.
AC   Q0P6D2;
DE   RecName: Full=Protein FAM69C;
GN   Name=FAM69C; Synonyms=C18orf51;
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
//
ID   FA71A_HUMAN             Reviewed;         594 AA.
AC   Q8IYT1; Q5VTZ1;
DE   RecName: Full=Protein FAM71A;
GN   Name=FAM71A;
//
ID   FA71B_HUMAN             Reviewed;         605 AA.
AC   Q8TC56; Q1EDD9; Q8TC64; Q96LY8;
DE   RecName: Full=Protein FAM71B;
GN   Name=FAM71B; ORFNames=HSD-51, HSD51;
//
ID   FA71C_HUMAN             Reviewed;         241 AA.
AC   Q8NEG0; B2R6Y6;
DE   RecName: Full=Protein FAM71C;
GN   Name=FAM71C;
//
ID   FA71D_HUMAN             Reviewed;         422 AA.
AC   Q8N9W8; Q86VN4;
DE   RecName: Full=Protein FAM71D;
GN   Name=FAM71D; Synonyms=C14orf54;
//
ID   FA72A_HUMAN             Reviewed;         149 AA.
AC   Q5TYM5; B2RV15; Q5TYM4;
DE   RecName: Full=Protein FAM72A;
DE   AltName: Full=Latent membrane protein 1-induced protein;
DE            Short=LMP1-induced protein;
DE            Short=LMPIP;
GN   Name=FAM72A; Synonyms=UGENE;
//
ID   FA72D_HUMAN             Reviewed;         149 AA.
AC   Q6L9T8;
DE   RecName: Full=Protein FAM72D;
DE   AltName: Full=Gastric cancer up-regulated protein 2;
GN   Name=FAM72D; Synonyms=GCUD2;
//
ID   FA72B_HUMAN             Reviewed;         149 AA.
AC   Q86X60; B2RPQ5; Q5QP15;
DE   RecName: Full=Protein FAM72B;
GN   Name=FAM72B;
//
ID   FA73A_HUMAN             Reviewed;         632 AA.
AC   Q8NAN2; Q6MZG0;
DE   RecName: Full=Protein FAM73A;
GN   Name=FAM73A;
//
ID   FA72C_HUMAN             Reviewed;         149 AA.
AC   H0Y354;
DE   RecName: Full=Protein FAM72C;
GN   Name=FAM72C;
//
ID   FA73B_HUMAN             Reviewed;         593 AA.
AC   Q7L4E1; Q8NBM3; Q8TEJ6; Q969E6;
DE   RecName: Full=Protein FAM73B;
GN   Name=FAM73B; Synonyms=C9orf54; ORFNames=PSEC0112;
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
//
ID   FA76A_HUMAN             Reviewed;         307 AA.
AC   Q8TAV0; B4DWT3; O95565; O95566; Q8N7J5;
DE   RecName: Full=Protein FAM76A;
GN   Name=FAM76A;
//
ID   FA76B_HUMAN             Reviewed;         339 AA.
AC   Q5HYJ3; Q6PIU3; Q8TC53;
DE   RecName: Full=Protein FAM76B;
GN   Name=FAM76B;
//
ID   FA78A_HUMAN             Reviewed;         283 AA.
AC   Q5JUQ0; Q86VQ9; Q9H7P4;
DE   RecName: Full=Protein FAM78A;
GN   Name=FAM78A; Synonyms=C9orf59;
//
ID   FA78B_HUMAN             Reviewed;         261 AA.
AC   Q5VT40; B7Z693;
DE   RecName: Full=Protein FAM78B;
GN   Name=FAM78B;
//
ID   FA7_HUMAN               Reviewed;         466 AA.
AC   P08709; B0YJC8; Q14339; Q5JVF1; Q5JVF2; Q9UD52; Q9UD53; Q9UD54;
DE   RecName: Full=Coagulation factor VII;
DE            EC=3.4.21.21;
DE   AltName: Full=Proconvertin;
DE   AltName: Full=Serum prothrombin conversion accelerator;
DE            Short=SPCA;
DE   AltName: INN=Eptacog alfa;
DE   Contains:
DE     RecName: Full=Factor VII light chain;
DE   Contains:
DE     RecName: Full=Factor VII heavy chain;
DE   Flags: Precursor;
GN   Name=F7;
DR   GuidetoPHARMACOLOGY; 2363; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007598; P:blood coagulation, extrinsic pathway; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; TAS:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0010641; P:positive regulation of platelet-derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0060416; P:response to growth hormone; IEA:Ensembl.
DR   GO; GO:0032571; P:response to vitamin K; IEA:Ensembl.
//
ID   FA81B_HUMAN             Reviewed;         452 AA.
AC   Q96LP2;
DE   RecName: Full=Protein FAM81B;
GN   Name=FAM81B;
//
ID   FA81A_HUMAN             Reviewed;         368 AA.
AC   Q8TBF8;
DE   RecName: Full=Protein FAM81A;
GN   Name=FAM81A;
//
ID   FA83B_HUMAN             Reviewed;        1011 AA.
AC   Q5T0W9; Q2M1P3; Q96DQ2;
DE   RecName: Full=Protein FAM83B;
GN   Name=FAM83B; Synonyms=C6orf143;
//
ID   FA83A_HUMAN             Reviewed;         434 AA.
AC   Q86UY5; Q71HL2; Q8N7I1; Q96I47;
DE   RecName: Full=Protein FAM83A;
DE   AltName: Full=Tumor antigen BJ-TSA-9;
DE   AltName: Full=Tumor-specific gene expressed in prostate protein;
GN   Name=FAM83A; Synonyms=TSGP;
//
ID   FA83C_HUMAN             Reviewed;         747 AA.
AC   Q9BQN1; Q14D67; Q5JWN6; Q8N276;
DE   RecName: Full=Protein FAM83C;
GN   Name=FAM83C; Synonyms=C20orf128;
//
ID   FA83D_HUMAN             Reviewed;         585 AA.
AC   Q9H4H8; B4E1I7; Q5THR2; Q68EN1; Q6P457; Q7Z6H0; Q96DF5; Q96N89;
AC   Q9BVM8;
DE   RecName: Full=Protein FAM83D;
DE   AltName: Full=Spindle protein CHICA;
GN   Name=FAM83D; Synonyms=C20orf129;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   FA83E_HUMAN             Reviewed;         478 AA.
AC   Q2M2I3; Q9NXK1;
DE   RecName: Full=Protein FAM83E;
GN   Name=FAM83E;
//
ID   FA83G_HUMAN             Reviewed;         823 AA.
AC   A6ND36; Q3KQZ4; Q6ZW60;
DE   RecName: Full=Protein FAM83G;
GN   Name=FAM83G;
//
ID   FA83F_HUMAN             Reviewed;         500 AA.
AC   Q8NEG4; Q96FD6;
DE   RecName: Full=Protein FAM83F;
GN   Name=FAM83F;
//
ID   FA83H_HUMAN             Reviewed;        1179 AA.
AC   Q6ZRV2; A0JLS2; Q8N4W0;
DE   RecName: Full=Protein FAM83H;
GN   Name=FAM83H;
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
//
ID   FA84A_HUMAN             Reviewed;         292 AA.
AC   Q96KN4; A6NP76; Q86UZ2; Q8NAH7; Q8TAM5;
DE   RecName: Full=Protein FAM84A;
DE   AltName: Full=Neurologic sensory protein 1;
DE            Short=NSE1;
GN   Name=FAM84A; Synonyms=NSE1;
//
ID   FA84B_HUMAN             Reviewed;         310 AA.
AC   Q96KN1;
DE   RecName: Full=Protein FAM84B;
DE   AltName: Full=Breast cancer membrane protein 101;
DE   AltName: Full=Protein NSE2;
GN   Name=FAM84B; Synonyms=BCMP101, NSE2;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
//
ID   FA86A_HUMAN             Reviewed;         330 AA.
AC   Q96G04; D3DUF0; Q96S85;
DE   RecName: Full=Protein FAM86A;
GN   Name=FAM86A; ORFNames=SB153;
//
ID   FA86C_HUMAN             Reviewed;         165 AA.
AC   Q9NVL1; Q8N5D3;
DE   RecName: Full=Protein FAM86C1;
DE   AltName: Full=Protein FAM86C;
GN   Name=FAM86C1; Synonyms=FAM86C;
//
ID   FA87A_HUMAN             Reviewed;         286 AA.
AC   P0C7U9;
DE   RecName: Full=Protein FAM87A;
GN   Name=FAM87A;
//
ID   FA87B_HUMAN             Reviewed;         159 AA.
AC   Q8N852;
DE   RecName: Full=Protein FAM87B;
GN   Name=FAM87B;
//
ID   FA89A_HUMAN             Reviewed;         184 AA.
AC   Q96GI7;
DE   RecName: Full=Protein FAM89A;
GN   Name=FAM89A; Synonyms=C1orf153;
//
ID   FA8A1_HUMAN             Reviewed;         413 AA.
AC   Q9UBU6; B2R725;
DE   RecName: Full=Protein FAM8A1;
DE   AltName: Full=Autosomal highly conserved protein;
GN   Name=FAM8A1; Synonyms=AHCP;
//
ID   FA89B_HUMAN             Reviewed;         189 AA.
AC   Q8N5H3; E9PB01; E9PL72; Q6PJ27;
DE   RecName: Full=Protein FAM89B;
GN   Name=FAM89B;
DR   GO; GO:0001222; F:transcription corepressor binding; ISS:UniProtKB.
DR   GO; GO:0060392; P:negative regulation of SMAD protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
//
ID   FA8_HUMAN               Reviewed;        2351 AA.
AC   P00451; Q14286; Q5HY69;
DE   RecName: Full=Coagulation factor VIII;
DE   AltName: Full=Antihemophilic factor;
DE            Short=AHF;
DE   AltName: Full=Procoagulant component;
DE   Contains:
DE     RecName: Full=Factor VIIIa heavy chain, 200 kDa isoform;
DE   Contains:
DE     RecName: Full=Factor VIIIa heavy chain, 92 kDa isoform;
DE   Contains:
DE     RecName: Full=Factor VIII B chain;
DE   Contains:
DE     RecName: Full=Factor VIIIa light chain;
DE   Flags: Precursor;
GN   Name=F8; Synonyms=F8C;
DR   GuidetoPHARMACOLOGY; 2607; -.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   FA92B_HUMAN             Reviewed;         304 AA.
AC   Q6ZTR7;
DE   RecName: Full=Protein FAM92B;
GN   Name=FAM92B;
//
ID   FA96A_HUMAN             Reviewed;         160 AA.
AC   Q9H5X1; A6NKS1; B2R5F8; B7Z8Z5;
DE   RecName: Full=MIP18 family protein FAM96A;
GN   Name=FAM96A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
//
ID   FA98A_HUMAN             Reviewed;         519 AA.
AC   Q8NCA5; B2RNA2; Q9Y3Y6;
DE   RecName: Full=Protein FAM98A;
GN   Name=FAM98A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   FA98C_HUMAN             Reviewed;         349 AA.
AC   Q17RN3; A6NMW3; Q66K45;
DE   RecName: Full=Protein FAM98C;
GN   Name=FAM98C;
//
ID   FA98B_HUMAN             Reviewed;         330 AA.
AC   Q52LJ0; A8MUW5; Q8N935;
DE   RecName: Full=Protein FAM98B;
GN   Name=FAM98B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   FA9_HUMAN               Reviewed;         461 AA.
AC   P00740; A8K9N4; F2RM36; Q5FBE1; Q5JYJ8;
DE   RecName: Full=Coagulation factor IX;
DE            EC=3.4.21.22;
DE   AltName: Full=Christmas factor;
DE   AltName: Full=Plasma thromboplastin component;
DE            Short=PTC;
DE   Contains:
DE     RecName: Full=Coagulation factor IXa light chain;
DE   Contains:
DE     RecName: Full=Coagulation factor IXa heavy chain;
DE   Flags: Precursor;
GN   Name=F9;
DR   GuidetoPHARMACOLOGY; 2364; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007598; P:blood coagulation, extrinsic pathway; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
//
ID   FAAA_HUMAN              Reviewed;         419 AA.
AC   P16930; B2R9X1; D3DW95;
DE   RecName: Full=Fumarylacetoacetase;
DE            Short=FAA;
DE            EC=3.7.1.2;
DE   AltName: Full=Beta-diketonase;
DE   AltName: Full=Fumarylacetoacetate hydrolase;
GN   Name=FAH;
DR   GO; GO:0004334; F:fumarylacetoacetase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006527; P:arginine catabolic process; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006572; P:tyrosine catabolic process; TAS:ProtInc.
//
ID   FAAH1_HUMAN             Reviewed;         579 AA.
AC   O00519; D3DQ19; Q52M86; Q5TDF8;
DE   RecName: Full=Fatty-acid amide hydrolase 1;
DE            EC=3.5.1.99;
DE   AltName: Full=Anandamide amidohydrolase 1;
DE   AltName: Full=Oleamide hydrolase 1;
GN   Name=FAAH; Synonyms=FAAH1;
DR   GuidetoPHARMACOLOGY; 1400; -.
DR   GO; GO:0047372; F:acylglycerol lipase activity; IEA:Ensembl.
DR   GO; GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.
DR   GO; GO:0017064; F:fatty acid amide hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0009062; P:fatty acid catabolic process; IDA:UniProtKB.
//
ID   FAAH2_HUMAN             Reviewed;         532 AA.
AC   Q6GMR7; Q86VT2; Q96N98;
DE   RecName: Full=Fatty-acid amide hydrolase 2;
DE            EC=3.5.1.99;
DE   AltName: Full=Amidase domain-containing protein;
DE   AltName: Full=Anandamide amidohydrolase 2;
DE   AltName: Full=Oleamide hydrolase 2;
GN   Name=FAAH2; Synonyms=AMDD;
DR   GuidetoPHARMACOLOGY; 1401; -.
DR   GO; GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   FABD_HUMAN              Reviewed;         390 AA.
AC   Q8IVS2; B0QY72; O95510; O95511;
DE   RecName: Full=Malonyl-CoA-acyl carrier protein transacylase, mitochondrial;
DE            Short=MCT;
DE            EC=2.3.1.39;
DE   AltName: Full=Mitochondrial malonyl CoA:ACP acyltransferase;
DE   AltName: Full=Mitochondrial malonyltransferase;
DE   AltName: Full=[Acyl-carrier-protein] malonyltransferase;
DE   Flags: Precursor;
GN   Name=MCAT; Synonyms=MT;
DR   GO; GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IDA:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
//
ID   FABP4_HUMAN             Reviewed;         132 AA.
AC   P15090; Q6IBA1;
DE   RecName: Full=Fatty acid-binding protein, adipocyte;
DE   AltName: Full=Adipocyte lipid-binding protein;
DE            Short=ALBP;
DE   AltName: Full=Adipocyte-type fatty acid-binding protein;
DE            Short=A-FABP;
DE            Short=AFABP;
DE   AltName: Full=Fatty acid-binding protein 4;
GN   Name=FABP4;
DR   GO; GO:0005504; F:fatty acid binding; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
DR   GO; GO:0050872; P:white fat cell differentiation; IEA:Ensembl.
//
ID   FABP5_HUMAN             Reviewed;         135 AA.
AC   Q01469; B2R4K0;
DE   RecName: Full=Fatty acid-binding protein, epidermal;
DE   AltName: Full=Epidermal-type fatty acid-binding protein;
DE            Short=E-FABP;
DE   AltName: Full=Fatty acid-binding protein 5;
DE   AltName: Full=Psoriasis-associated fatty acid-binding protein homolog;
DE            Short=PA-FABP;
GN   Name=FABP5;
DR   GO; GO:0005504; F:fatty acid binding; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
//
ID   FABP6_HUMAN             Reviewed;         128 AA.
AC   P51161; Q07DR7; Q8TBI3; Q9UGI7;
DE   RecName: Full=Gastrotropin;
DE            Short=GT;
DE   AltName: Full=Fatty acid-binding protein 6;
DE   AltName: Full=Ileal lipid-binding protein;
DE            Short=ILBP;
DE   AltName: Full=Intestinal 15 kDa protein;
DE            Short=I-15P;
DE   AltName: Full=Intestinal bile acid-binding protein;
DE            Short=I-BABP;
GN   Name=FABP6; Synonyms=ILBP, ILLBP;
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FABP7_HUMAN             Reviewed;         132 AA.
AC   O15540; B2R4L1; O14951; Q6IAU7;
DE   RecName: Full=Fatty acid-binding protein, brain;
DE   AltName: Full=Brain lipid-binding protein;
DE            Short=BLBP;
DE   AltName: Full=Brain-type fatty acid-binding protein;
DE            Short=B-FABP;
DE   AltName: Full=Fatty acid-binding protein 7;
DE   AltName: Full=Mammary-derived growth inhibitor related;
GN   Name=FABP7; Synonyms=BLBP, FABPB, MRG;
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
//
ID   FABP9_HUMAN             Reviewed;         132 AA.
AC   Q0Z7S8;
DE   RecName: Full=Fatty acid-binding protein 9;
DE   AltName: Full=Testis lipid-binding protein;
DE            Short=TLBP;
DE   AltName: Full=Testis-type fatty acid-binding protein;
DE            Short=T-FABP;
GN   Name=FABP9;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
//
ID   FABPH_HUMAN             Reviewed;         133 AA.
AC   P05413; B2RAB6; Q5VV93; Q99957;
DE   RecName: Full=Fatty acid-binding protein, heart;
DE   AltName: Full=Fatty acid-binding protein 3;
DE   AltName: Full=Heart-type fatty acid-binding protein;
DE            Short=H-FABP;
DE   AltName: Full=Mammary-derived growth inhibitor;
DE            Short=MDGI;
DE   AltName: Full=Muscle fatty acid-binding protein;
DE            Short=M-FABP;
GN   Name=FABP3; Synonyms=FABP11, MDGI;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0050543; F:icosatetraenoic acid binding; IEA:Ensembl.
DR   GO; GO:0036041; F:long-chain fatty acid binding; IDA:BHF-UCL.
DR   GO; GO:0005324; F:long-chain fatty acid transporter activity; IEA:Ensembl.
DR   GO; GO:0070538; F:oleic acid binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0044539; P:long-chain fatty acid import; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0055091; P:phospholipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0071073; P:positive regulation of phospholipid biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0046320; P:regulation of fatty acid oxidation; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   FABPI_HUMAN             Reviewed;         132 AA.
AC   P12104; Q2NKJ1;
DE   RecName: Full=Fatty acid-binding protein, intestinal;
DE   AltName: Full=Fatty acid-binding protein 2;
DE   AltName: Full=Intestinal-type fatty acid-binding protein;
DE            Short=I-FABP;
GN   Name=FABP2; Synonyms=FABPI;
DR   GO; GO:0005504; F:fatty acid binding; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
//
ID   FABPL_HUMAN             Reviewed;         127 AA.
AC   P07148;
DE   RecName: Full=Fatty acid-binding protein, liver;
DE   AltName: Full=Fatty acid-binding protein 1;
DE   AltName: Full=Liver-type fatty acid-binding protein;
DE            Short=L-FABP;
GN   Name=FABP1; Synonyms=FABPL;
DR   GO; GO:0016209; F:antioxidant activity; IDA:UniProtKB.
DR   GO; GO:0032052; F:bile acid binding; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0005504; F:fatty acid binding; IEA:Ensembl.
DR   GO; GO:0005324; F:long-chain fatty acid transporter activity; IEA:Ensembl.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IEA:Ensembl.
DR   GO; GO:0051345; P:positive regulation of hydrolase activity; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FACD2_HUMAN             Reviewed;        1471 AA.
AC   Q9BXW9; Q2LA86; Q69YP9; Q6PJN7; Q9BQ06; Q9H9T9;
DE   RecName: Full=Fanconi anemia group D2 protein;
DE            Short=Protein FACD2;
GN   Name=FANCD2; Synonyms=FACD;
DR   GO; GO:0070182; F:DNA polymerase binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   FACOS_HUMAN             Reviewed;         177 AA.
AC   Q96PS1;
DE   RecName: Full=FANCD2 opposite strand protein;
DE   AltName: Full=Fanconi anemia group D2 protein opposite strand transcript protein;
GN   Name=FANCD2OS; Synonyms=C3orf24; ORFNames=HSD19;
//
ID   FACE2_HUMAN             Reviewed;         329 AA.
AC   Q9Y256; Q52LZ9;
DE   RecName: Full=CAAX prenyl protease 2;
DE            EC=3.4.22.-;
DE   AltName: Full=Farnesylated proteins-converting enzyme 2;
DE            Short=FACE-2;
DE   AltName: Full=Prenyl protein-specific endoprotease 2;
DE   AltName: Full=RCE1 homolog;
DE            Short=hRCE1;
GN   Name=RCE1; Synonyms=FACE2, RCE1A, RCE1B;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0071586; P:CAAX-box protein processing; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   FACE1_HUMAN             Reviewed;         475 AA.
AC   O75844; B3KQI7; D3DPU7; Q8NDZ8; Q9UBQ2;
DE   RecName: Full=CAAX prenyl protease 1 homolog;
DE            EC=3.4.24.84;
DE   AltName: Full=Farnesylated proteins-converting enzyme 1;
DE            Short=FACE-1;
DE   AltName: Full=Prenyl protein-specific endoprotease 1;
DE   AltName: Full=Zinc metalloproteinase Ste24 homolog;
GN   Name=ZMPSTE24; Synonyms=FACE1, STE24;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008235; F:metalloexopeptidase activity; TAS:ProtInc.
DR   GO; GO:0006998; P:nuclear envelope organization; IEA:Ensembl.
DR   GO; GO:0030327; P:prenylated protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   FACR1_HUMAN             Reviewed;         515 AA.
AC   Q8WVX9; D3DQW8; Q5CZA3;
DE   RecName: Full=Fatty acyl-CoA reductase 1;
DE            EC=1.2.1.n2;
DE   AltName: Full=Male sterility domain-containing protein 2;
GN   Name=FAR1; Synonyms=MLSTD2; ORFNames=UNQ2423/PRO4981;
DR   GO; GO:0080019; F:fatty-acyl-CoA reductase (alcohol-forming) activity; IDA:UniProtKB.
DR   GO; GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008611; P:ether lipid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0035336; P:long-chain fatty-acyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0010025; P:wax biosynthetic process; IEA:Ensembl.
//
ID   FAD1_HUMAN              Reviewed;         587 AA.
AC   Q8NFF5; Q8N5J1; Q8N686; Q8WU93; Q8WUJ4; Q96CR8; Q99764; Q9HBN6;
DE   RecName: Full=FAD synthase;
DE            EC=2.7.7.2;
DE   AltName: Full=FAD pyrophosphorylase;
DE   AltName: Full=FMN adenylyltransferase;
DE   AltName: Full=Flavin adenine dinucleotide synthase;
DE   Includes:
DE     RecName: Full=Molybdenum cofactor biosynthesis protein-like region;
DE   Includes:
DE     RecName: Full=FAD synthase region;
DE   Flags: Precursor;
GN   Name=FLAD1; ORFNames=PP591;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003919; F:FMN adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006747; P:FAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:InterPro.
DR   GO; GO:0006771; P:riboflavin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   FACR2_HUMAN             Reviewed;         515 AA.
AC   Q96K12; Q9H0D5; Q9NVW8;
DE   RecName: Full=Fatty acyl-CoA reductase 2;
DE            EC=1.2.1.n2;
DE   AltName: Full=Male sterility domain-containing protein 1;
GN   Name=FAR2; Synonyms=MLSTD1;
DR   GO; GO:0080019; F:fatty-acyl-CoA reductase (alcohol-forming) activity; IDA:UniProtKB.
DR   GO; GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008611; P:ether lipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0035336; P:long-chain fatty-acyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FADD_HUMAN              Reviewed;         208 AA.
AC   Q13158; Q14866; Q6IBR4;
DE   RecName: Full=FAS-associated death domain protein;
DE   AltName: Full=FAS-associating death domain-containing protein;
DE   AltName: Full=Growth-inhibiting gene 3 protein;
DE   AltName: Full=Mediator of receptor induced toxicity;
DE   AltName: Full=Protein FADD;
GN   Name=FADD; Synonyms=MORT1; ORFNames=GIG3;
DR   GO; GO:0035877; F:death effector domain binding; IPI:UniProtKB.
DR   GO; GO:0005123; F:death receptor binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032813; F:tumor necrosis factor receptor superfamily binding; IPI:UniProtKB.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048535; P:lymph node development; ISS:UniProtKB.
DR   GO; GO:0097049; P:motor neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097527; P:necroptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0070236; P:negative regulation of activation-induced cell death of T cells; ISS:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0002821; P:positive regulation of adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000454; P:positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation; ISS:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0048536; P:spleen development; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0048538; P:thymus development; ISS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FADS1_HUMAN             Reviewed;         444 AA.
AC   O60427; A8K0I7; B2RAI0; Q53GM5; Q8N3A6; Q8NCC7; Q8NCG0; Q96I39;
AC   Q96SV3; Q96T10; Q9NRP8; Q9NYX1;
DE   RecName: Full=Fatty acid desaturase 1;
DE            EC=1.14.19.-;
DE   AltName: Full=Delta(5) fatty acid desaturase;
DE            Short=D5D;
DE            Short=Delta(5) desaturase;
DE            Short=Delta-5 desaturase;
GN   Name=FADS1; Synonyms=FADSD5;
DR   GO; GO:0000248; F:C-5 sterol desaturase activity; TAS:ProtInc.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0009267; P:cellular response to starvation; IDA:UniProtKB.
DR   GO; GO:0046456; P:icosanoid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0009744; P:response to sucrose; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
//
ID   FADS2_HUMAN             Reviewed;         444 AA.
AC   O95864; A8K2M6; B7Z634; Q6MZQ7; Q96H07; Q96SV8; Q9H3G3; Q9Y3X4;
DE   RecName: Full=Fatty acid desaturase 2;
DE            EC=1.14.19.-;
DE   AltName: Full=Delta(6) fatty acid desaturase;
DE            Short=D6D;
DE            Short=Delta(6) desaturase;
DE            Short=Delta-6 desaturase;
GN   Name=FADS2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR   GO; GO:0004768; F:stearoyl-CoA 9-desaturase activity; IEA:Ensembl.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0043651; P:linoleic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
//
ID   FADS3_HUMAN             Reviewed;         445 AA.
AC   Q9Y5Q0; O60426;
DE   RecName: Full=Fatty acid desaturase 3;
DE            EC=1.14.19.-;
DE   AltName: Full=Cytochrome b5-related protein;
GN   Name=FADS3; Synonyms=CYB5RP;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; NAS:UniProtKB.
//
ID   FADS6_HUMAN             Reviewed;         356 AA.
AC   Q8N9I5; Q17RQ7; Q6XYE1;
DE   RecName: Full=Fatty acid desaturase 6;
DE            EC=1.14.19.-;
GN   Name=FADS6; ORFNames=FP18279;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
//
ID   FAF1_HUMAN              Reviewed;         650 AA.
AC   Q9UNN5; Q549F0; Q9UF34; Q9UNT3; Q9Y2Z3;
DE   RecName: Full=FAS-associated factor 1;
DE            Short=hFAF1;
DE   AltName: Full=UBX domain-containing protein 12;
DE   AltName: Full=UBX domain-containing protein 3A;
GN   Name=FAF1; Synonyms=UBXD12, UBXN3A; ORFNames=CGI-03;
DR   GO; GO:0031072; F:heat shock protein binding; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0019887; F:protein kinase regulator activity; NAS:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IMP:UniProtKB.
DR   GO; GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; NAS:GOC.
//
ID   FAF2_HUMAN              Reviewed;         445 AA.
AC   Q96CS3; O94963; Q8IUF2; Q9BRP2; Q9BVM7;
DE   RecName: Full=FAS-associated factor 2;
DE   AltName: Full=Protein ETEA;
DE   AltName: Full=UBX domain-containing protein 3B;
DE   AltName: Full=UBX domain-containing protein 8;
GN   Name=FAF2; Synonyms=ETEA, KIAA0887, UBXD8, UBXN3B;
DR   GO; GO:0035473; F:lipase binding; IDA:MGI.
DR   GO; GO:0055102; F:lipase inhibitor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.
DR   GO; GO:0034389; P:lipid particle organization; IMP:MGI.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   FAH2A_HUMAN             Reviewed;         314 AA.
AC   Q96GK7; Q9Y3B0;
DE   RecName: Full=Fumarylacetoacetate hydrolase domain-containing protein 2A;
DE            EC=3.-.-.-;
GN   Name=FAHD2A; ORFNames=CGI-105;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   FAH2B_HUMAN             Reviewed;         314 AA.
AC   Q6P2I3; D3DXH7; Q8NDK1;
DE   RecName: Full=Fumarylacetoacetate hydrolase domain-containing protein 2B;
DE            EC=3.-.-.-;
GN   Name=FAHD2B;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   FAHD1_HUMAN             Reviewed;         224 AA.
AC   Q6P587; B1AK40; B1AK41; Q6FIC7; Q96RY1; Q9H0N6;
DE   RecName: Full=Acylpyruvase FAHD1, mitochondrial;
DE            EC=3.7.1.5;
DE   AltName: Full=Fumarylacetoacetate hydrolase domain-containing protein 1;
DE   AltName: Full=YisK-like protein;
DE   Flags: Precursor;
GN   Name=FAHD1; Synonyms=C16orf36, YISKL;
DR   GO; GO:0018773; F:acetylpyruvate hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0047621; F:acylpyruvate hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034545; F:fumarylpyruvate hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   FAIM3_HUMAN             Reviewed;         390 AA.
AC   O60667; A8K7J2; B7Z6Z0; D9MWM3;
DE   RecName: Full=Fas apoptotic inhibitory molecule 3;
DE   AltName: Full=Regulator of Fas-induced apoptosis Toso;
DE   Flags: Precursor;
GN   Name=FAIM3; Synonyms=TOSO;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
//
ID   FAIM1_HUMAN             Reviewed;         179 AA.
AC   Q9NVQ4; Q6IAN2;
DE   RecName: Full=Fas apoptotic inhibitory molecule 1;
GN   Name=FAIM; Synonyms=FAIM1;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
//
ID   FAK1_HUMAN              Reviewed;        1052 AA.
AC   Q05397; B4E2N6; F5H4S4; Q14291; Q9UD85;
DE   RecName: Full=Focal adhesion kinase 1;
DE            Short=FADK 1;
DE            EC=2.7.10.2;
DE   AltName: Full=Focal adhesion kinase-related nonkinase;
DE            Short=FRNK;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 71;
DE            Short=PPP1R71;
DE   AltName: Full=Protein-tyrosine kinase 2;
DE   AltName: Full=p125FAK;
DE   AltName: Full=pp125FAK;
GN   Name=PTK2; Synonyms=FAK, FAK1;
DR   GuidetoPHARMACOLOGY; 2180; -.
DR   GO; GO:0003779; F:actin binding; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008432; F:JUN kinase binding; IDA:BHF-UCL.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:Reactome.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048870; P:cell motility; TAS:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0021955; P:central nervous system neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; TAS:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; TAS:UniProtKB.
DR   GO; GO:0040023; P:establishment of nucleus localization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0051964; P:negative regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0038007; P:netrin-activated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001890; P:placenta development; TAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0010594; P:regulation of endothelial cell migration; TAS:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:UniProtKB.
DR   GO; GO:0007172; P:signal complex assembly; IEA:InterPro.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   FAK2_HUMAN              Reviewed;        1009 AA.
AC   Q14289; D3DST0; Q13475; Q14290; Q16709; Q6PID4;
DE   RecName: Full=Protein-tyrosine kinase 2-beta;
DE            EC=2.7.10.2;
DE   AltName: Full=Calcium-dependent tyrosine kinase;
DE            Short=CADTK;
DE   AltName: Full=Calcium-regulated non-receptor proline-rich tyrosine kinase;
DE   AltName: Full=Cell adhesion kinase beta;
DE            Short=CAK-beta;
DE            Short=CAKB;
DE   AltName: Full=Focal adhesion kinase 2;
DE            Short=FADK 2;
DE   AltName: Full=Proline-rich tyrosine kinase 2;
DE   AltName: Full=Related adhesion focal tyrosine kinase;
DE            Short=RAFTK;
GN   Name=PTK2B; Synonyms=FAK2, PYK2, RAFTK;
DR   GuidetoPHARMACOLOGY; 2181; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; NAS:ProtInc.
DR   GO; GO:0042976; P:activation of Janus kinase activity; IMP:UniProtKB.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0045453; P:bone resorption; ISS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0014009; P:glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0002315; P:marginal zone B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010656; P:negative regulation of muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:UniProtKB.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:2000538; P:positive regulation of B cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0050848; P:regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0030826; P:regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010752; P:regulation of cGMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0010758; P:regulation of macrophage chemotaxis; ISS:UniProtKB.
DR   GO; GO:0045428; P:regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:2000058; P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0007172; P:signal complex assembly; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0043149; P:stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   FAKD1_HUMAN             Reviewed;         847 AA.
AC   Q53R41; Q8N583; Q8TEA9; Q96JM5; Q96N71; Q9H6T4;
DE   RecName: Full=FAST kinase domain-containing protein 1;
GN   Name=FASTKD1; Synonyms=KIAA1800;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; ISS:UniProtKB.
//
ID   FAKD2_HUMAN             Reviewed;         710 AA.
AC   Q9NYY8; Q9NVX6; Q9Y2H7;
DE   RecName: Full=FAST kinase domain-containing protein 2;
GN   Name=FASTKD2; Synonyms=KIAA0971;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; ISS:UniProtKB.
//
ID   FAKD5_HUMAN             Reviewed;         764 AA.
AC   Q7L8L6; Q96JN3; Q9H5D1; Q9H8Y3;
DE   RecName: Full=FAST kinase domain-containing protein 5;
GN   Name=FASTKD5; Synonyms=KIAA1792;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; ISS:UniProtKB.
//
ID   FAKD3_HUMAN             Reviewed;         662 AA.
AC   Q14CZ7; Q9BVD3;
DE   RecName: Full=FAST kinase domain-containing protein 3;
GN   Name=FASTKD3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0045333; P:cellular respiration; IMP:UniProtKB.
//
ID   FAM3A_HUMAN             Reviewed;         230 AA.
AC   P98173; A6QRH6; B2RBI7; B4DFI8; D3DWX4; Q5HY76; Q96H51;
DE   RecName: Full=Protein FAM3A;
DE   AltName: Full=Cytokine-like protein 2-19;
DE   Flags: Precursor;
GN   Name=FAM3A; Synonyms=2-19, 2.19;
//
ID   FAM27_HUMAN             Reviewed;          67 AA.
AC   Q5VT28;
DE   RecName: Full=Protein FAM27A/B/C;
GN   Name=FAM27A; Synonyms=FAM27A1;
GN   and
GN   Name=FAM27B; Synonyms=FAM27A2;
GN   and
GN   Name=FAM27C; Synonyms=FAM27A3;
//
ID   FAM3B_HUMAN             Reviewed;         235 AA.
AC   P58499;
DE   RecName: Full=Protein FAM3B;
DE   AltName: Full=Cytokine-like protein 2-21;
DE   AltName: Full=Pancreatic-derived factor;
DE            Short=PANDER;
DE   Flags: Precursor;
GN   Name=FAM3B; Synonyms=C21orf11, C21orf76;
GN   ORFNames=PRED44, UNQ320/PRO365;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030073; P:insulin secretion; IDA:UniProtKB.
//
ID   FAM3C_HUMAN             Reviewed;         227 AA.
AC   Q92520; A6NDN2; A8K3R7;
DE   RecName: Full=Protein FAM3C;
DE   AltName: Full=Interleukin-like EMT inducer;
DE   Flags: Precursor;
GN   Name=FAM3C; Synonyms=ILEI; ORFNames=GS3786;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   FAM3D_HUMAN             Reviewed;         224 AA.
AC   Q96BQ1; Q547G2;
DE   RecName: Full=Protein FAM3D;
DE   Flags: Precursor;
GN   Name=FAM3D; ORFNames=UNQ567/PRO1130;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IDA:UniProtKB.
//
ID   FAM74_HUMAN             Reviewed;         123 AA.
AC   Q5TZK3; A6NH89; Q6ZSU6;
DE   RecName: Full=Protein FAM74A4/A6;
GN   Name=FAM74A4;
GN   and
GN   Name=FAM74A6;
//
ID   FAM9C_HUMAN             Reviewed;         166 AA.
AC   Q8IZT9; B2R9G7; Q5HYJ6;
DE   RecName: Full=Protein FAM9C;
GN   Name=FAM9C;
//
ID   FAM9B_HUMAN             Reviewed;         186 AA.
AC   Q8IZU0; Q0IJ68;
DE   RecName: Full=Protein FAM9B;
GN   Name=FAM9B;
//
ID   FAM9A_HUMAN             Reviewed;         332 AA.
AC   Q8IZU1; B7ZLH5; Q2M2D1;
DE   RecName: Full=Protein FAM9A;
GN   Name=FAM9A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FANCA_HUMAN             Reviewed;        1455 AA.
AC   O15360; A5D923; B4DRI7; H3BSR5; O75266; Q6PL10; Q92497; Q96H18;
AC   Q9UEA5; Q9UEL8; Q9UEL9; Q9UPK3; Q9Y6M2;
DE   RecName: Full=Fanconi anemia group A protein;
DE            Short=Protein FACA;
GN   Name=FANCA; Synonyms=FAA, FACA, FANCH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
//
ID   FANCB_HUMAN             Reviewed;         859 AA.
AC   Q8NB91; B2RMZ4; Q7Z2U2; Q86XG1;
DE   RecName: Full=Fanconi anemia group B protein;
DE            Short=Protein FACB;
DE   AltName: Full=Fanconi anemia-associated polypeptide of 95 kDa;
DE            Short=FAAP95;
GN   Name=FANCB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   FAN1_HUMAN              Reviewed;        1017 AA.
AC   Q9Y2M0; A8K4M2; Q86WU8;
DE   RecName: Full=Fanconi-associated nuclease 1;
DE            EC=3.1.21.-;
DE            EC=3.1.4.1;
DE   AltName: Full=FANCD2/FANCI-associated nuclease 1;
DE   AltName: Full=Myotubularin-related protein 15;
GN   Name=FAN1; Synonyms=KIAA1018, MTMR15;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; TAS:UniProtKB.
DR   GO; GO:0004528; F:phosphodiesterase I activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0033683; P:nucleotide-excision repair, DNA incision; IDA:UniProtKB.
//
ID   FANCC_HUMAN             Reviewed;         558 AA.
AC   Q00597; B1ALR8;
DE   RecName: Full=Fanconi anemia group C protein;
DE            Short=Protein FACC;
GN   Name=FANCC; Synonyms=FAC, FACC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0002262; P:myeloid cell homeostasis; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0019430; P:removal of superoxide radicals; IEA:Ensembl.
//
ID   FANCE_HUMAN             Reviewed;         536 AA.
AC   Q9HB96; A8K907; Q4ZGH2;
DE   RecName: Full=Fanconi anemia group E protein;
DE            Short=Protein FACE;
GN   Name=FANCE; Synonyms=FACE;
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   FANCF_HUMAN             Reviewed;         374 AA.
AC   Q9NPI8; Q52LM0;
DE   RecName: Full=Fanconi anemia group F protein;
DE            Short=Protein FACF;
GN   Name=FANCF;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   FANCG_HUMAN             Reviewed;         622 AA.
AC   O15287;
DE   RecName: Full=Fanconi anemia group G protein;
DE            Short=Protein FACG;
DE   AltName: Full=DNA repair protein XRCC9;
GN   Name=FANCG; Synonyms=XRCC9;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   FANCI_HUMAN             Reviewed;        1328 AA.
AC   Q9NVI1; A4ZVE4; A5YMH4; A6NJZ0; Q96JN1; Q96ST0; Q9BT96;
DE   RecName: Full=Fanconi anemia group I protein;
DE            Short=Protein FACI;
GN   Name=FANCI; Synonyms=KIAA1794;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0070182; F:DNA polymerase binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:MGI.
//
ID   FANCJ_HUMAN             Reviewed;        1249 AA.
AC   Q9BX63; Q3MJE2; Q8NCI5;
DE   RecName: Full=Fanconi anemia group J protein;
DE            Short=Protein FACJ;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase BRIP1;
DE   AltName: Full=BRCA1-associated C-terminal helicase 1;
DE   AltName: Full=BRCA1-interacting protein C-terminal helicase 1;
DE            Short=BRCA1-interacting protein 1;
GN   Name=BRIP1; Synonyms=BACH1, FANCJ;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; NAS:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; NAS:GOC.
DR   GO; GO:0006302; P:double-strand break repair; NAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FANCL_HUMAN             Reviewed;         375 AA.
AC   Q9NW38; Q6GU60;
DE   RecName: Full=E3 ubiquitin-protein ligase FANCL;
DE            EC=6.3.2.-;
DE   AltName: Full=Fanconi anemia group L protein;
DE   AltName: Full=Fanconi anemia-associated polypeptide of 43 kDa;
DE            Short=FAAP43;
GN   Name=FANCL; Synonyms=PHF9;
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
//
ID   FANCM_HUMAN             Reviewed;        2048 AA.
AC   Q8IYD8; B2RTQ9; Q3YFH9; Q8N9X6; Q9HCH6;
DE   RecName: Full=Fanconi anemia group M protein;
DE            Short=Protein FACM;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase FANCM;
DE   AltName: Full=Fanconi anemia-associated polypeptide of 250 kDa;
DE            Short=FAAP250;
DE   AltName: Full=Protein Hef ortholog;
GN   Name=FANCM; Synonyms=KIAA1596;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006259; P:DNA metabolic process; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IMP:UniProtKB.
//
ID   FANK1_HUMAN             Reviewed;         345 AA.
AC   Q8TC84; Q6UXY9; Q6X7T6;
DE   RecName: Full=Fibronectin type 3 and ankyrin repeat domains protein 1;
GN   Name=FANK1; ORFNames=HSD13, UNQ6504/PRO21382;
//
ID   FAN_HUMAN               Reviewed;         917 AA.
AC   Q92636; B4DFB0; E9PCH0; Q8IW26;
DE   RecName: Full=Protein FAN;
DE   AltName: Full=Factor associated with neutral sphingomyelinase activation;
DE            Short=Factor associated with N-SMase activation;
GN   Name=NSMAF; Synonyms=FAN;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0016230; F:sphingomyelin phosphodiesterase activator activity; IEA:Ensembl.
DR   GO; GO:0006672; P:ceramide metabolic process; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FAP20_HUMAN             Reviewed;         180 AA.
AC   Q6NZ36; A6PW39; A6PW40; A6PW41; A8MQT6; F2Z2L4; Q6ZT64; Q71M24;
AC   Q96ND7;
DE   RecName: Full=Fanconi anemia-associated protein of 20 kDa;
GN   Name=FAAP20; Synonyms=C1orf86; ORFNames=FP7162;
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0036297; P:interstrand cross-link repair; IMP:UniProtKB.
DR   GO; GO:0019985; P:translesion synthesis; IMP:UniProtKB.
//
ID   FAP24_HUMAN             Reviewed;         215 AA.
AC   Q9BTP7; B3KY46; Q8WUJ7; Q96FX6;
DE   RecName: Full=Fanconi anemia-associated protein of 24 kDa;
GN   Name=FAAP24; Synonyms=C19orf40;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   FARP1_HUMAN             Reviewed;        1045 AA.
AC   Q9Y4F1; Q5JVI9; Q6IQ29;
DE   RecName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 1;
DE   AltName: Full=Chondrocyte-derived ezrin-like protein;
DE   AltName: Full=Pleckstrin homology domain-containing family C member 2;
DE            Short=PH domain-containing family C member 2;
GN   Name=FARP1; Synonyms=CDEP, PLEKHC2;
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0007416; P:synapse assembly; ISS:UniProtKB.
//
ID   FARP2_HUMAN             Reviewed;        1054 AA.
AC   O94887; B7Z6J8; F5GZ84; Q53QM5; Q8WU27; Q9UFE7;
DE   RecName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2;
DE   AltName: Full=FERM domain including RhoGEF;
DE            Short=FIR;
DE   AltName: Full=Pleckstrin homology domain-containing family C member 3;
DE            Short=PH domain-containing family C member 3;
GN   Name=FARP2; Synonyms=KIAA0793, PLEKHC3;
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0016322; P:neuron remodeling; IDA:MGI.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0071800; P:podosome assembly; ISS:UniProtKB.
DR   GO; GO:0016601; P:Rac protein signal transduction; IDA:MGI.
DR   GO; GO:0033623; P:regulation of integrin activation; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
//
ID   FASTK_HUMAN             Reviewed;         549 AA.
AC   Q14296; A8K867; F8VTW9; Q59EM8; Q8IVA0;
DE   RecName: Full=Fas-activated serine/threonine kinase;
DE            Short=FAST kinase;
DE            EC=2.7.11.8;
GN   Name=FASTK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0033867; F:Fas-activated serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
//
ID   FAS_HUMAN               Reviewed;        2511 AA.
AC   P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68;
AC   Q96IT0;
DE   RecName: Full=Fatty acid synthase;
DE            EC=2.3.1.85;
DE   Includes:
DE     RecName: Full=[Acyl-carrier-protein] S-acetyltransferase;
DE              EC=2.3.1.38;
DE   Includes:
DE     RecName: Full=[Acyl-carrier-protein] S-malonyltransferase;
DE              EC=2.3.1.39;
DE   Includes:
DE     RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase;
DE              EC=2.3.1.41;
DE   Includes:
DE     RecName: Full=3-oxoacyl-[acyl-carrier-protein] reductase;
DE              EC=1.1.1.100;
DE   Includes:
DE     RecName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase;
DE              EC=4.2.1.59;
DE   Includes:
DE     RecName: Full=Enoyl-[acyl-carrier-protein] reductase;
DE              EC=1.3.1.39;
DE   Includes:
DE     RecName: Full=Oleoyl-[acyl-carrier-protein] hydrolase;
DE              EC=3.1.2.14;
GN   Name=FASN; Synonyms=FAS;
DR   GO; GO:0047451; F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; IEA:InterPro.
DR   GO; GO:0004316; F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004313; F:[acyl-carrier-protein] S-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004314; F:[acyl-carrier-protein] S-malonyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0047117; F:enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004319; F:enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity; IEA:InterPro.
DR   GO; GO:0004312; F:fatty acid synthase activity; TAS:Reactome.
DR   GO; GO:0016295; F:myristoyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070402; F:NADPH binding; IEA:Ensembl.
DR   GO; GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; TAS:ProtInc.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   FAT1_HUMAN              Reviewed;        4588 AA.
AC   Q14517;
DE   RecName: Full=Protocadherin Fat 1;
DE   AltName: Full=Cadherin family member 7;
DE   AltName: Full=Cadherin-related tumor suppressor homolog;
DE   AltName: Full=Protein fat homolog;
DE   Contains:
DE     RecName: Full=Protocadherin Fat 1, nuclear form;
DE   Flags: Precursor;
GN   Name=FAT1; Synonyms=CDHF7, FAT;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; ISS:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   FAT2_HUMAN              Reviewed;        4349 AA.
AC   Q9NYQ8; O75091; Q9NSR7;
DE   RecName: Full=Protocadherin Fat 2;
DE            Short=hFat2;
DE   AltName: Full=Cadherin family member 8;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 1;
DE            Short=Multiple EGF-like domains protein 1;
DE   Flags: Precursor;
GN   Name=FAT2; Synonyms=CDHF8, KIAA0811, MEGF1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0010631; P:epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.
//
ID   FAT3_HUMAN              Reviewed;        4589 AA.
AC   Q8TDW7; B5MDB0; Q96AU6;
DE   RecName: Full=Protocadherin Fat 3;
DE            Short=hFat3;
DE   AltName: Full=Cadherin family member 15;
DE   AltName: Full=FAT tumor suppressor homolog 3;
DE   Flags: Precursor;
GN   Name=FAT3; Synonyms=CDHF15, KIAA1989;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   FAT4_HUMAN              Reviewed;        4981 AA.
AC   Q6V0I7; A8K5Z6; B5MDG4; Q3LIA6; Q8TCK7; Q9H5T6;
DE   RecName: Full=Protocadherin Fat 4;
DE            Short=hFat4;
DE   AltName: Full=Cadherin family member 14;
DE   AltName: Full=FAT tumor suppressor homolog 4;
DE   AltName: Full=Fat-like cadherin protein FAT-J;
DE   Flags: Precursor;
GN   Name=FAT4; Synonyms=CDHF14, FATJ; ORFNames=Nbla00548;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
//
ID   FATE1_HUMAN             Reviewed;         183 AA.
AC   Q969F0;
DE   RecName: Full=Fetal and adult testis-expressed transcript protein;
DE   AltName: Full=Cancer/testis antigen 43;
DE            Short=CT43;
DE   AltName: Full=Tumor antigen BJ-HCC-2;
GN   Name=FATE1; Synonyms=FATE;
//
ID   FAXC_HUMAN              Reviewed;         409 AA.
AC   Q5TGI0; B3KU39; Q96F61; Q96LU3; Q9BSS2;
DE   RecName: Full=Failed axon connections homolog;
GN   Name=FAXC; Synonyms=C6orf168;
//
ID   FB5L3_HUMAN             Reviewed;         101 AA.
AC   A8MUU1;
DE   RecName: Full=Putative fatty acid-binding protein 5-like protein 3;
DE   AltName: Full=Fatty acid-binding protein 5 pseudogene 3;
GN   Name=FABP5P3; Synonyms=FABP5L3;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   FBCD1_HUMAN             Reviewed;         461 AA.
AC   Q8N539; A3KFK0; Q6UXK6; Q96SJ7;
DE   RecName: Full=Fibrinogen C domain-containing protein 1;
GN   Name=FIBCD1; ORFNames=UNQ701/PRO1346;
DR   GO; GO:0008061; F:chitin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   FBAS1_HUMAN             Reviewed;         122 AA.
AC   Q494R0; Q3KR42; Q8NAQ9;
DE   RecName: Full=Putative uncharacterized protein FBXL19-AS1;
DE   AltName: Full=FBXL19 antisense RNA 1;
DE   AltName: Full=FBXL19 antisense gene protein 1;
GN   Name=FBXL19-AS1; Synonyms=NCRNA00095;
//
ID   FBF1_HUMAN              Reviewed;        1133 AA.
AC   Q8TES7; B5MEM5; Q96IF6; Q96JG4; Q96MA8;
DE   RecName: Full=Fas-binding factor 1;
DE            Short=FBF-1;
DE   AltName: Full=Protein albatross;
GN   Name=FBF1; Synonyms=ALB, KIAA1863;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043297; P:apical junction assembly; IMP:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IMP:UniProtKB.
//
ID   FBLI1_HUMAN             Reviewed;         373 AA.
AC   Q8WUP2; B3KNY0; Q5VVE0; Q5VVE1; Q8IX23; Q96T00; Q9UFD6;
DE   RecName: Full=Filamin-binding LIM protein 1;
DE            Short=FBLP-1;
DE   AltName: Full=Migfilin;
DE   AltName: Full=Mitogen-inducible 2-interacting protein;
DE            Short=MIG2-interacting protein;
GN   Name=FBLIM1; Synonyms=FBLP1;
DR   GO; GO:0031005; F:filamin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0033623; P:regulation of integrin activation; IMP:UniProtKB.
//
ID   FBLL1_HUMAN             Reviewed;         333 AA.
AC   A6NHQ2;
DE   RecName: Full=rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1;
DE            EC=2.1.1.-;
DE   AltName: Full=Protein-glutamine methyltransferase;
GN   Name=FBLL1;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:InterPro.
//
ID   FBLN1_HUMAN             Reviewed;         703 AA.
AC   P23142; B0QY42; P23143; P23144; P37888; Q5TIC4; Q8TBH8; Q9HBQ5;
AC   Q9UC21; Q9UGR4; Q9UH41;
DE   RecName: Full=Fibulin-1;
DE            Short=FIBL-1;
DE   Flags: Precursor;
GN   Name=FBLN1; ORFNames=PP213;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0016504; F:peptidase activator activity; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FBLN2_HUMAN             Reviewed;        1184 AA.
AC   P98095; B7Z9C5; Q8IUI0; Q8IUI1;
DE   RecName: Full=Fibulin-2;
DE            Short=FIBL-2;
DE   Flags: Precursor;
GN   Name=FBLN2;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   FBLN3_HUMAN             Reviewed;         493 AA.
AC   Q12805; A8K3I4; B4DW75; D6W5D2; Q541U7;
DE   RecName: Full=EGF-containing fibulin-like extracellular matrix protein 1;
DE   AltName: Full=Extracellular protein S1-5;
DE   AltName: Full=Fibrillin-like protein;
DE   AltName: Full=Fibulin-3;
DE            Short=FIBL-3;
DE   Flags: Precursor;
GN   Name=EFEMP1; Synonyms=FBLN3, FBNL;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0005006; F:epidermal growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   FBLN4_HUMAN             Reviewed;         443 AA.
AC   O95967; A8K7R4; B3KM31; B3KQT1; O75967;
DE   RecName: Full=EGF-containing fibulin-like extracellular matrix protein 2;
DE   AltName: Full=Fibulin-4;
DE            Short=FIBL-4;
DE   AltName: Full=Protein UPH1;
DE   Flags: Precursor;
GN   Name=EFEMP2; Synonyms=FBLN4; ORFNames=UNQ200/PRO226;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   FBLN5_HUMAN             Reviewed;         448 AA.
AC   Q9UBX5; O75966; Q6IAL4; Q6UWA3;
DE   RecName: Full=Fibulin-5;
DE            Short=FIBL-5;
DE   AltName: Full=Developmental arteries and neural crest EGF-like protein;
DE            Short=Dance;
DE   AltName: Full=Urine p50 protein;
DE            Short=UP50;
DE   Flags: Precursor;
GN   Name=FBLN5; Synonyms=DANCE; ORFNames=UNQ184/PRO210;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0048251; P:elastic fiber assembly; ISS:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0034394; P:protein localization to cell surface; ISS:BHF-UCL.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:2000121; P:regulation of removal of superoxide radicals; ISS:BHF-UCL.
//
ID   FBLN7_HUMAN             Reviewed;         439 AA.
AC   Q53RD9; A0JNV1; A0JNV2; Q5H9P5; Q8N9G0;
DE   RecName: Full=Fibulin-7;
DE            Short=FIBL-7;
DE   Flags: Precursor;
GN   Name=FBLN7; Synonyms=TM14;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   FBN1_HUMAN              Reviewed;        2871 AA.
AC   P35555; B2RUU0; D2JYH6; Q15972; Q75N87;
DE   RecName: Full=Fibrillin-1;
DE   Flags: Precursor;
GN   Name=FBN1; Synonyms=FBN;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0035582; P:sequestering of BMP in extracellular matrix; ISS:BHF-UCL.
DR   GO; GO:0035583; P:sequestering of TGFbeta in extracellular matrix; ISS:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
//
ID   FBN2_HUMAN              Reviewed;        2912 AA.
AC   P35556; B4DU01; Q59ES6;
DE   RecName: Full=Fibrillin-2;
DE   Flags: Precursor;
GN   Name=FBN2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0060346; P:bone trabecula formation; ISS:BHF-UCL.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; ISS:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0035583; P:sequestering of TGFbeta in extracellular matrix; ISS:BHF-UCL.
//
ID   FBN3_HUMAN              Reviewed;        2809 AA.
AC   Q75N90; Q75N91; Q75N92; Q75N93; Q86SJ5; Q96JP8;
DE   RecName: Full=Fibrillin-3;
DE   Flags: Precursor;
GN   Name=FBN3; Synonyms=KIAA1776;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IEA:InterPro.
//
ID   FBP12_HUMAN             Reviewed;         140 AA.
AC   A6NFH5; B7SUN0;
DE   RecName: Full=Fatty acid-binding protein 12;
GN   Name=FABP12;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   FBP1L_HUMAN             Reviewed;         605 AA.
AC   Q5T0N5; Q5T0N6; Q6B097; Q6P653; Q6R4Q4; Q9NXG1;
DE   RecName: Full=Formin-binding protein 1-like;
DE   AltName: Full=Transducer of Cdc42-dependent actin assembly protein 1;
DE            Short=Toca-1;
GN   Name=FNBP1L; Synonyms=C1orf39, TOCA1;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0072583; P:clathrin-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0006900; P:membrane budding; IDA:BHF-UCL.
DR   GO; GO:0010324; P:membrane invagination; IDA:BHF-UCL.
DR   GO; GO:0097320; P:membrane tubulation; IDA:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.
DR   GO; GO:0016050; P:vesicle organization; IDA:BHF-UCL.
DR   GO; GO:0030050; P:vesicle transport along actin filament; IDA:BHF-UCL.
//
ID   FBRL_HUMAN              Reviewed;         321 AA.
AC   P22087; B5BUE8; O75259; Q6IAT5; Q9UPI6;
DE   RecName: Full=rRNA 2'-O-methyltransferase fibrillarin;
DE            EC=2.1.1.-;
DE   AltName: Full=34 kDa nucleolar scleroderma antigen;
DE   AltName: Full=Histone-glutamine methyltransferase;
GN   Name=FBL; Synonyms=FIB1, FLRN;
DR   GO; GO:1990259; F:histone-glutamine methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:1990258; P:histone glutamine methylation; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
DR   GO; GO:0016074; P:snoRNA metabolic process; IEA:Ensembl.
DR   GO; GO:0008033; P:tRNA processing; IEA:InterPro.
//
ID   FBRS_HUMAN              Reviewed;         460 AA.
AC   Q9HAH7; B4DP86; Q96CI9; Q9H9X4;
DE   RecName: Full=Probable fibrosin-1;
GN   Name=FBRS; Synonyms=FBS, FBS1;
//
ID   FBSL_HUMAN              Reviewed;        1045 AA.
AC   Q9HCM7; Q86XQ1;
DE   RecName: Full=Fibrosin-1-like protein;
DE   AltName: Full=AUTS2-like protein;
DE   AltName: Full=HBV X-transactivated gene 9 protein;
DE   AltName: Full=HBV XAg-transactivated protein 9;
GN   Name=FBRSL1; Synonyms=AUTS2L, KIAA1545, XTP9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   FBSP1_HUMAN             Reviewed;         286 AA.
AC   P0C2W1; A6NF90; D3DXB5;
DE   RecName: Full=F-box/SPRY domain-containing protein 1;
DE   AltName: Full=F-box only protein 45;
DE            Short=hFbxo45;
GN   Name=FBXO45; Synonyms=FBX45;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBW10_HUMAN             Reviewed;        1052 AA.
AC   Q5XX13; C9JRY8; C9JZD7; Q8TC00; Q9H0F0;
DE   RecName: Full=F-box/WD repeat-containing protein 10;
DE   AltName: Full=F-box and WD-40 domain-containing protein 10;
DE   AltName: Full=Ubiquitin ligase-specificity factor;
GN   Name=FBXW10;
//
ID   FBW12_HUMAN             Reviewed;         464 AA.
AC   Q6X9E4; E9PG36; Q494Y9; Q494Z0;
DE   RecName: Full=F-box/WD repeat-containing protein 12;
DE   AltName: Full=F-box and WD-40 domain-containing protein 12;
DE   AltName: Full=F-box only protein 35;
GN   Name=FBXW12; Synonyms=FBW12, FBXO12, FBXO35;
//
ID   FBW1A_HUMAN             Reviewed;         605 AA.
AC   Q9Y297; B5MD49; Q5W141; Q5W142; Q9Y213;
DE   RecName: Full=F-box/WD repeat-containing protein 1A;
DE   AltName: Full=E3RSIkappaB;
DE   AltName: Full=Epididymis tissue protein Li 2a;
DE   AltName: Full=F-box and WD repeats protein beta-TrCP;
DE   AltName: Full=pIkappaBalpha-E3 receptor subunit;
GN   Name=BTRC; Synonyms=BTRCP, FBW1A, FBXW1A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0031648; P:protein destabilization; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IEA:Ensembl.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   FBW1B_HUMAN             Reviewed;         542 AA.
AC   Q9UKB1; B2RC98; Q9P2S8; Q9P2S9; Q9Y4C6;
DE   RecName: Full=F-box/WD repeat-containing protein 11;
DE   AltName: Full=F-box and WD repeats protein beta-TrCP2;
DE   AltName: Full=F-box/WD repeat-containing protein 1B;
DE   AltName: Full=Homologous to Slimb protein;
DE            Short=HOS;
GN   Name=FBXW11; Synonyms=BTRCP2, FBW1B, FBXW1B, KIAA0696;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   FBX10_HUMAN             Reviewed;         956 AA.
AC   Q9UK96; Q08AL3; Q5JRT8; Q9UKC3;
DE   RecName: Full=F-box only protein 10;
GN   Name=FBXO10; Synonyms=FBX10, PRMT11;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
//
ID   FBX11_HUMAN             Reviewed;         927 AA.
AC   Q86XK2; A1L491; Q52ZP1; Q53EP7; Q53RT5; Q8IXG3; Q96E90; Q9H6V8;
AC   Q9H9L1; Q9NR14; Q9UFK1; Q9UHI1; Q9UKC2;
DE   RecName: Full=F-box only protein 11;
DE   AltName: Full=Protein arginine N-methyltransferase 9;
DE   AltName: Full=Vitiligo-associated protein 1;
DE            Short=VIT-1;
GN   Name=FBXO11; Synonyms=FBX11, PRMT9, VIT1; ORFNames=UG063H01;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:HGNC.
DR   GO; GO:0035246; P:peptidyl-arginine N-methylation; IDA:GOC.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
//
ID   FBX15_HUMAN             Reviewed;         510 AA.
AC   Q8NCQ5; B3KST3;
DE   RecName: Full=F-box only protein 15;
GN   Name=FBXO15; Synonyms=FBX15;
//
ID   FBX16_HUMAN             Reviewed;         292 AA.
AC   Q8IX29; Q3T1B2; Q3T1B3; Q3T1B4;
DE   RecName: Full=F-box only protein 16;
GN   Name=FBXO16; Synonyms=FBX16;
//
ID   FBX17_HUMAN             Reviewed;         278 AA.
AC   Q96EF6; Q96LQ4;
DE   RecName: Full=F-box only protein 17;
DE   AltName: Full=F-box only protein 26;
GN   Name=FBXO17; Synonyms=FBG4, FBX17, FBX26, FBXO26;
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
//
ID   FBX18_HUMAN             Reviewed;        1043 AA.
AC   Q8NFZ0; Q5JVB0; Q5JVB1; Q7Z4Q6; Q7Z4R0; Q8N1P5; Q8N586; Q96E82;
AC   Q96K67; Q96SW7; Q9UFB2;
DE   RecName: Full=F-box only protein 18;
DE            EC=3.6.4.12;
DE   AltName: Full=F-box DNA helicase 1;
GN   Name=FBXO18; Synonyms=FBH1, FBX18;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FBX21_HUMAN             Reviewed;         628 AA.
AC   O94952; B3KMF0; Q5BJG0; Q9H087;
DE   RecName: Full=F-box only protein 21;
GN   Name=FBXO21; Synonyms=FBX21, KIAA0875;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:GOC.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
//
ID   FBX22_HUMAN             Reviewed;         403 AA.
AC   Q8NEZ5; Q0D2P8; Q6PIL5; Q8IXW3; Q9H824; Q9UKC0;
DE   RecName: Full=F-box only protein 22;
DE   AltName: Full=F-box protein FBX22p44;
GN   Name=FBXO22; Synonyms=FBX22;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0048742; P:regulation of skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   FBX24_HUMAN             Reviewed;         580 AA.
AC   O75426; A4D2D4; B4DX91; B4DY42; Q9H0G1;
DE   RecName: Full=F-box only protein 24;
GN   Name=FBXO24; Synonyms=FBX24;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
//
ID   FBX25_HUMAN             Reviewed;         367 AA.
AC   Q8TCJ0; Q6PJ83; Q7Z4V4; Q9UKB8;
DE   RecName: Full=F-box only protein 25;
GN   Name=FBXO25; Synonyms=FBX25;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   FBX27_HUMAN             Reviewed;         283 AA.
AC   Q8NI29; Q96C87;
DE   RecName: Full=F-box only protein 27;
DE   AltName: Full=F-box/G-domain protein 5;
GN   Name=FBXO27; Synonyms=FBG5, FBX27;
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
//
ID   FBX28_HUMAN             Reviewed;         368 AA.
AC   Q9NVF7; E9PEM8; O75070;
DE   RecName: Full=F-box only protein 28;
GN   Name=FBXO28; Synonyms=KIAA0483;
//
ID   FBX2_HUMAN              Reviewed;         296 AA.
AC   Q9UK22; B2R7K7; Q5TGY0; Q6FGJ7; Q8TB29; Q9UKC6;
DE   RecName: Full=F-box only protein 2;
GN   Name=FBXO2; Synonyms=FBX2;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006516; P:glycoprotein catabolic process; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   FBX30_HUMAN             Reviewed;         745 AA.
AC   Q8TB52; Q9BXZ7;
DE   RecName: Full=F-box only protein 30;
GN   Name=FBXO30; Synonyms=FBX30;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   FBX32_HUMAN             Reviewed;         355 AA.
AC   Q969P5; A4KYM0;
DE   RecName: Full=F-box only protein 32;
DE   AltName: Full=Atrogin-1;
DE   AltName: Full=Muscle atrophy F-box protein;
DE            Short=MAFbx;
GN   Name=FBXO32;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; ISS:UniProtKB.
//
ID   FBX31_HUMAN             Reviewed;         539 AA.
AC   Q5XUX0; Q5K680; Q8WYV1; Q96D73; Q9UFV4;
DE   RecName: Full=F-box only protein 31;
GN   Name=FBXO31; Synonyms=FBX14, FBX31; ORFNames=PP2386;
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0008054; P:cyclin catabolic process; IMP:UniProtKB.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBX33_HUMAN             Reviewed;         555 AA.
AC   Q7Z6M2; Q6PIR2; Q86TR2; Q86YE0;
DE   RecName: Full=F-box only protein 33;
GN   Name=FBXO33; Synonyms=FBX33;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   FBX34_HUMAN             Reviewed;         711 AA.
AC   Q9NWN3; Q2VPB5; Q86TY4;
DE   RecName: Full=F-box only protein 34;
GN   Name=FBXO34; Synonyms=FBX34;
//
ID   FBX36_HUMAN             Reviewed;         188 AA.
AC   Q8NEA4; B3KVQ6; Q53TE6; Q8WWD4;
DE   RecName: Full=F-box only protein 36;
GN   Name=FBXO36; Synonyms=FBX36;
//
ID   FBX38_HUMAN             Reviewed;        1188 AA.
AC   Q6PIJ6; Q6PK72; Q7Z2U0; Q86VN3; Q9BXY6; Q9H837; Q9HC40;
DE   RecName: Full=F-box only protein 38;
DE   AltName: Full=Modulator of KLF7 activity homolog;
DE            Short=MoKA;
GN   Name=FBXO38; ORFNames=SP329;
//
ID   FBX39_HUMAN             Reviewed;         442 AA.
AC   Q8N4B4;
DE   RecName: Full=F-box only protein 39;
GN   Name=FBXO39; Synonyms=FBX39;
//
ID   FBX3_HUMAN              Reviewed;         471 AA.
AC   Q9UK99; B3KY16; D3DR05; Q86X90; Q9H0V2; Q9NUX2;
DE   RecName: Full=F-box only protein 3;
GN   Name=FBXO3; Synonyms=FBX3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   FBX40_HUMAN             Reviewed;         709 AA.
AC   Q9UH90; B2RAX7; Q32M70; Q9ULM5;
DE   RecName: Full=F-box only protein 40;
DE   AltName: Full=Muscle disease-related protein;
GN   Name=FBXO40; Synonyms=FBX40, KIAA1195;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042692; P:muscle cell differentiation; ISS:UniProtKB.
//
ID   FBX41_HUMAN             Reviewed;         875 AA.
AC   Q8TF61; G3V0Z7; Q2M1V8;
DE   RecName: Full=F-box only protein 41;
GN   Name=FBXO41; Synonyms=FBX41, KIAA1940;
//
ID   FBX42_HUMAN             Reviewed;         717 AA.
AC   Q6P3S6; B3KP30; Q5TEU8; Q86XI0; Q8N3N4; Q8N5F8; Q9BRM0; Q9P2L4;
DE   RecName: Full=F-box only protein 42;
DE   AltName: Full=Just one F-box and Kelch domain-containing protein;
GN   Name=FBXO42; Synonyms=FBX42, JFK, KIAA1332;
//
ID   FBX43_HUMAN             Reviewed;         708 AA.
AC   Q4G163;
DE   RecName: Full=F-box only protein 43;
DE   AltName: Full=Endogenous meiotic inhibitor 2;
GN   Name=FBXO43; Synonyms=EMI2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0045835; P:negative regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   FBX44_HUMAN             Reviewed;         255 AA.
AC   Q9H4M3; B3KNZ2; B7Z743; Q5TGX2; Q5TGX4; Q5TGX5; Q68DJ9; Q8WWY2;
DE   RecName: Full=F-box only protein 44;
DE   AltName: Full=F-box protein FBX30;
DE   AltName: Full=F-box/G-domain protein 3;
GN   Name=FBXO44; Synonyms=FBG3, FBX30, FBX44, FBX6A, FBXO6A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
//
ID   FBX47_HUMAN             Reviewed;         452 AA.
AC   Q5MNV8; B2RTZ4;
DE   RecName: Full=F-box only protein 47;
GN   Name=FBXO47;
//
ID   FBX46_HUMAN             Reviewed;         603 AA.
AC   Q6PJ61;
DE   RecName: Full=F-box only protein 46;
DE   AltName: Full=F-box only protein 34-like;
GN   Name=FBXO46; Synonyms=FBX46, FBXO34L;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FBX4_HUMAN              Reviewed;         387 AA.
AC   Q9UKT5; Q68CU8; Q86VT8; Q9UK98;
DE   RecName: Full=F-box only protein 4;
GN   Name=FBXO4; Synonyms=FBX4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBX48_HUMAN             Reviewed;         155 AA.
AC   Q5FWF7;
DE   RecName: Full=F-box only protein 48;
GN   Name=FBXO48; Synonyms=FBX48;
//
ID   FBX50_HUMAN             Reviewed;         275 AA.
AC   Q6ZVX7; Q6NVV5;
DE   RecName: Full=F-box only protein 50;
DE   AltName: Full=NCC receptor protein 1 homolog;
DE            Short=NCCRP-1;
DE   AltName: Full=Non-specific cytotoxic cell receptor protein 1 homolog;
GN   Name=NCCRP1; Synonyms=FBXO50;
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
//
ID   FBX6_HUMAN              Reviewed;         293 AA.
AC   Q9NRD1; B1AK42; B2RC88; Q9UKT3;
DE   RecName: Full=F-box only protein 6;
DE   AltName: Full=F-box protein that recognizes sugar chains 2;
DE   AltName: Full=F-box/G-domain protein 2;
GN   Name=FBXO6; Synonyms=FBG2, FBS2, FBX6;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0001948; F:glycoprotein binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0000077; P:DNA damage checkpoint; TAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBX5_HUMAN              Reviewed;         447 AA.
AC   Q9UKT4; B3KNX5; Q5TF47; Q8WV29; Q9UGC8;
DE   RecName: Full=F-box only protein 5;
DE   AltName: Full=Early mitotic inhibitor 1;
GN   Name=FBXO5; Synonyms=EMI1, FBX5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0060565; P:inhibition of mitotic anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046785; P:microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045835; P:negative regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007057; P:spindle assembly involved in female meiosis I; IEA:Ensembl.
DR   GO; GO:0016050; P:vesicle organization; IEA:Ensembl.
//
ID   FBX7_HUMAN              Reviewed;         522 AA.
AC   Q9Y3I1; B4DNB3; B4DWX5; Q5TGC4; Q5TI86; Q96HM6; Q9UF21; Q9UKT2;
DE   RecName: Full=F-box only protein 7;
GN   Name=FBXO7; Synonyms=FBX7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   FBX8_HUMAN              Reviewed;         319 AA.
AC   Q9NRD0; B2RB40; D3DP41; Q6UWN4; Q9NRP5; Q9UKC4;
DE   RecName: Full=F-box only protein 8;
DE   AltName: Full=F-box/SEC7 protein FBS;
GN   Name=FBXO8; Synonyms=FBS, FBX8; ORFNames=DC10, UNQ1877/PRO4320;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
//
ID   FBX9_HUMAN              Reviewed;         447 AA.
AC   Q9UK97; A6NFW3; B3KMM6; O75986; Q59EH8; Q6PKH7; Q9NT57; Q9Y593;
DE   RecName: Full=F-box only protein 9;
DE   AltName: Full=Cross-immune reaction antigen 1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-57;
GN   Name=FBXO9; Synonyms=FBX9, VCIA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0032006; P:regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBXL2_HUMAN             Reviewed;         423 AA.
AC   Q9UKC9; B4DQV0; E9PD06; Q6IAN3; Q9NVQ8; Q9UK27; Q9UKA5; Q9Y3Y9;
DE   RecName: Full=F-box/LRR-repeat protein 2;
DE   AltName: Full=F-box and leucine-rich repeat protein 2;
DE   AltName: Full=F-box protein FBL2/FBL3;
GN   Name=FBXL2; Synonyms=FBL2, FBL3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FBXL3_HUMAN             Reviewed;         428 AA.
AC   Q9UKT7; B2RB04; Q9P122;
DE   RecName: Full=F-box/LRR-repeat protein 3;
DE   AltName: Full=F-box and leucine-rich repeat protein 3A;
DE   AltName: Full=F-box/LRR-repeat protein 3A;
GN   Name=FBXL3; Synonyms=FBL3A, FBXL3A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBXL4_HUMAN             Reviewed;         621 AA.
AC   Q9UKA2; E1P530; O95919; Q5BJH0; Q9UJU0;
DE   RecName: Full=F-box/LRR-repeat protein 4;
DE   AltName: Full=F-box and leucine-rich repeat protein 4;
DE   AltName: Full=F-box protein FBL4/FBL5;
GN   Name=FBXL4; Synonyms=FBL4, FBL5;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   FBXL5_HUMAN             Reviewed;         691 AA.
AC   Q9UKA1; A8MSK4; B4DIB5; Q4W5A8; Q8NHP3; Q9NXN2; Q9P0I0; Q9P0X5;
AC   Q9UJT7; Q9UKC8;
DE   RecName: Full=F-box/LRR-repeat protein 5;
DE   AltName: Full=F-box and leucine-rich repeat protein 5;
DE   AltName: Full=F-box protein FBL4/FBL5;
DE   AltName: Full=p45SKP2-like protein;
GN   Name=FBXL5; Synonyms=FBL4, FBL5, FLR1;
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0055072; P:iron ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBXL6_HUMAN             Reviewed;         539 AA.
AC   Q8N531; Q53G43; Q9H5W9; Q9UKC7;
DE   RecName: Full=F-box/LRR-repeat protein 6;
DE   AltName: Full=F-box and leucine-rich repeat protein 6;
DE   AltName: Full=F-box protein FBL6;
DE   AltName: Full=FBL6A;
GN   Name=FBXL6; Synonyms=FBL6;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   FBXL7_HUMAN             Reviewed;         491 AA.
AC   Q9UJT9; B9EGF1; D6RDY7; O94926;
DE   RecName: Full=F-box/LRR-repeat protein 7;
DE   AltName: Full=F-box and leucine-rich repeat protein 7;
DE   AltName: Full=F-box protein FBL6/FBL7;
GN   Name=FBXL7; Synonyms=FBL6, FBL7, KIAA0840;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
//
ID   FBXL8_HUMAN             Reviewed;         374 AA.
AC   Q96CD0; Q9NUM0;
DE   RecName: Full=F-box/LRR-repeat protein 8;
DE   AltName: Full=F-box and leucine-rich repeat protein 8;
DE   AltName: Full=F-box protein FBL8;
GN   Name=FBXL8; Synonyms=FBL8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FBXW2_HUMAN             Reviewed;         454 AA.
AC   Q9UKT8; B3KRL8; Q4VXH2; Q7Z4V6; Q8WV51; Q9HA09; Q9UKA3;
DE   RecName: Full=F-box/WD repeat-containing protein 2;
DE   AltName: Full=F-box and WD-40 domain-containing protein 2;
DE   AltName: Full=Protein MD6;
GN   Name=FBXW2; Synonyms=FBW2, FWD2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   FBXW4_HUMAN             Reviewed;         412 AA.
AC   P57775; Q5SVS1; Q96IM6;
DE   RecName: Full=F-box/WD repeat-containing protein 4;
DE   AltName: Full=Dactylin;
DE   AltName: Full=F-box and WD-40 domain-containing protein 4;
GN   Name=FBXW4; Synonyms=FBW4, SHFM3;
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; NAS:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   FBXW5_HUMAN             Reviewed;         566 AA.
AC   Q969U6; B2RDZ6; Q59ET5; Q5SPZ8; Q5SPZ9; Q5SQ00; Q5SQ02; Q5SQ03;
AC   Q5SQ04; Q8WY79; Q96GJ6; Q9BSU8; Q9H6A8; Q9HBQ6; Q9NSZ3;
DE   RecName: Full=F-box/WD repeat-containing protein 5;
DE   AltName: Full=F-box and WD-40 domain-containing protein 5;
GN   Name=FBXW5; Synonyms=FBW5; ORFNames=PP3971;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FBXW7_HUMAN             Reviewed;         707 AA.
AC   Q969H0; B7ZLP9; Q68DR0; Q96A16; Q96LE0; Q96RI2; Q9NUX6;
DE   RecName: Full=F-box/WD repeat-containing protein 7;
DE   AltName: Full=Archipelago homolog;
DE            Short=hAgo;
DE   AltName: Full=F-box and WD-40 domain-containing protein 7;
DE   AltName: Full=F-box protein FBX30;
DE   AltName: Full=SEL-10;
DE   AltName: Full=hCdc4;
GN   Name=FBXW7; Synonyms=FBW7, FBX30, SEL10;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.
DR   GO; GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.
DR   GO; GO:2000639; P:negative regulation of SREBP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.
DR   GO; GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0001944; P:vasculature development; TAS:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FBXW8_HUMAN             Reviewed;         598 AA.
AC   Q8N3Y1; Q9UK95;
DE   RecName: Full=F-box/WD repeat-containing protein 8;
DE   AltName: Full=F-box and WD-40 domain-containing protein 8;
DE   AltName: Full=F-box only protein 29;
GN   Name=FBXW8; Synonyms=FBW6, FBW8, FBX29, FBXO29, FBXW6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IGI:UniProtKB.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IDA:UniProtKB.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEA:Ensembl.
//
ID   FBXW9_HUMAN             Reviewed;         488 AA.
AC   Q5XUX1; B3KVP7; Q9BT89;
DE   RecName: Full=F-box/WD repeat-containing protein 9;
DE   AltName: Full=F-box and WD-40 domain-containing protein 9;
GN   Name=FBXW9; Synonyms=FBW9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   FCAMR_HUMAN             Reviewed;         532 AA.
AC   Q8WWV6; Q32M82; Q8WWV5; Q96SA2;
DE   RecName: Full=High affinity immunoglobulin alpha and immunoglobulin mu Fc receptor;
DE   AltName: Full=Fc alpha/mu receptor;
DE   AltName: CD_antigen=CD351;
DE   Flags: Precursor;
GN   Name=FCAMR; ORFNames=FKSG87;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   FCAR_HUMAN              Reviewed;         287 AA.
AC   P24071; Q13603; Q13604; Q15727; Q15728; Q1AJL7; Q1AJL8; Q1AJL9;
AC   Q53X38; Q53X39; Q92587; Q92588; Q92590; Q92592; Q92593; Q9UEK0;
DE   RecName: Full=Immunoglobulin alpha Fc receptor;
DE            Short=IgA Fc receptor;
DE   AltName: CD_antigen=CD89;
DE   Flags: Precursor;
GN   Name=FCAR; Synonyms=CD89;
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   FCER2_HUMAN             Reviewed;         321 AA.
AC   P06734;
DE   RecName: Full=Low affinity immunoglobulin epsilon Fc receptor;
DE   AltName: Full=BLAST-2;
DE   AltName: Full=C-type lectin domain family 4 member J;
DE   AltName: Full=Fc-epsilon-RII;
DE   AltName: Full=Immunoglobulin E-binding factor;
DE   AltName: Full=Lymphocyte IgE receptor;
DE   AltName: CD_antigen=CD23;
DE   Contains:
DE     RecName: Full=Low affinity immunoglobulin epsilon Fc receptor membrane-bound form;
DE   Contains:
DE     RecName: Full=Low affinity immunoglobulin epsilon Fc receptor soluble form;
GN   Name=FCER2; Synonyms=CD23A, CLEC4J, FCE2, IGEBF;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0051712; P:positive regulation of killing of cells of other organism; IDA:BHF-UCL.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IDA:BHF-UCL.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.
//
ID   FCERA_HUMAN             Reviewed;         257 AA.
AC   P12319;
DE   RecName: Full=High affinity immunoglobulin epsilon receptor subunit alpha;
DE   AltName: Full=Fc-epsilon RI-alpha;
DE            Short=FcERI;
DE   AltName: Full=IgE Fc receptor subunit alpha;
DE   Flags: Precursor;
GN   Name=FCER1A; Synonyms=FCE1A;
DR   GO; GO:0019767; F:IgE receptor activity; IEA:Ensembl.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0045425; P:positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045401; P:positive regulation of interleukin-3 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0001812; P:positive regulation of type I hypersensitivity; IEA:Ensembl.
DR   GO; GO:0001820; P:serotonin secretion; IEA:Ensembl.
//
ID   FCERB_HUMAN             Reviewed;         244 AA.
AC   Q01362; Q54A81;
DE   RecName: Full=High affinity immunoglobulin epsilon receptor subunit beta;
DE            Short=FcERI;
DE   AltName: Full=Fc epsilon receptor I beta-chain;
DE   AltName: Full=IgE Fc receptor subunit beta;
DE   AltName: Full=Membrane-spanning 4-domains subfamily A member 2;
GN   Name=MS4A2; Synonyms=APY, FCER1B, IGER;
DR   GO; GO:0007202; P:activation of phospholipase C activity; IEA:Ensembl.
DR   GO; GO:0050663; P:cytokine secretion; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; IMP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
//
ID   FCERG_HUMAN             Reviewed;          86 AA.
AC   P30273; Q5VTW4;
DE   RecName: Full=High affinity immunoglobulin epsilon receptor subunit gamma;
DE   AltName: Full=Fc receptor gamma-chain;
DE            Short=FcRgamma;
DE   AltName: Full=Fc-epsilon RI-gamma;
DE   AltName: Full=IgE Fc receptor subunit gamma;
DE            Short=FceRI gamma;
DE   Flags: Precursor;
GN   Name=FCER1G;
DR   GO; GO:0019767; F:IgE receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; IEA:Ensembl.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0045576; P:mast cell activation; IEA:Ensembl.
DR   GO; GO:0033026; P:negative regulation of mast cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0002283; P:neutrophil activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0032765; P:positive regulation of mast cell cytokine production; IEA:Ensembl.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0001812; P:positive regulation of type I hypersensitivity; IEA:Ensembl.
DR   GO; GO:0001798; P:positive regulation of type IIa hypersensitivity; IEA:Ensembl.
DR   GO; GO:0001805; P:positive regulation of type III hypersensitivity; IEA:Ensembl.
DR   GO; GO:0010543; P:regulation of platelet activation; IEA:Ensembl.
DR   GO; GO:0002554; P:serotonin secretion by platelet; IEA:Ensembl.
//
ID   FCF1_HUMAN              Reviewed;         198 AA.
AC   Q9Y324; Q86TW8; Q8TBL8;
DE   RecName: Full=rRNA-processing protein FCF1 homolog;
GN   Name=FCF1; Synonyms=C14orf111; ORFNames=CGI-35;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   FCG2A_HUMAN             Reviewed;         317 AA.
AC   P12318; Q8WUN1; Q8WW64;
DE   RecName: Full=Low affinity immunoglobulin gamma Fc region receptor II-a;
DE            Short=IgG Fc receptor II-a;
DE   AltName: Full=CDw32;
DE   AltName: Full=Fc-gamma RII-a;
DE            Short=Fc-gamma-RIIa;
DE            Short=FcRII-a;
DE   AltName: CD_antigen=CD32;
DE   Flags: Precursor;
GN   Name=FCGR2A; Synonyms=CD32, FCG2, FCGR2A1, IGFR2;
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   FCG2B_HUMAN             Reviewed;         310 AA.
AC   P31994; A6H8N3; O95649; Q53X85; Q5VXA9; Q8NIA1;
DE   RecName: Full=Low affinity immunoglobulin gamma Fc region receptor II-b;
DE            Short=IgG Fc receptor II-b;
DE   AltName: Full=CDw32;
DE   AltName: Full=Fc-gamma RII-b;
DE            Short=Fc-gamma-RIIb;
DE            Short=FcRII-b;
DE   AltName: CD_antigen=CD32;
DE   Flags: Precursor;
GN   Name=FCGR2B; Synonyms=CD32, FCG2, IGFR2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FCG2C_HUMAN             Reviewed;         323 AA.
AC   P31995; O00523; O00524; O00525;
DE   RecName: Full=Low affinity immunoglobulin gamma Fc region receptor II-c;
DE            Short=IgG Fc receptor II-c;
DE   AltName: Full=CDw32;
DE   AltName: Full=Fc-gamma RII-c;
DE            Short=Fc-gamma-RIIc;
DE            Short=FcRII-c;
DE   AltName: CD_antigen=CD32;
DE   Flags: Precursor;
GN   Name=FCGR2C; Synonyms=CD32, FCG2, IGFR2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   FCG3A_HUMAN             Reviewed;         254 AA.
AC   P08637; A2N6W9; Q53FJ0; Q53FL6; Q5EBR4; Q65ZM6; Q6PIJ0;
DE   RecName: Full=Low affinity immunoglobulin gamma Fc region receptor III-A;
DE   AltName: Full=CD16a antigen;
DE   AltName: Full=Fc-gamma RIII-alpha;
DE            Short=Fc-gamma RIII;
DE            Short=Fc-gamma RIIIa;
DE            Short=FcRIII;
DE            Short=FcRIIIa;
DE   AltName: Full=FcR-10;
DE   AltName: Full=IgG Fc receptor III-2;
DE   AltName: CD_antigen=CD16a;
DE   Flags: Precursor;
GN   Name=FCGR3A; Synonyms=CD16A, FCG3, FCGR3, IGFR3;
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   FCG3B_HUMAN             Reviewed;         233 AA.
AC   O75015;
DE   RecName: Full=Low affinity immunoglobulin gamma Fc region receptor III-B;
DE   AltName: Full=Fc-gamma RIII-beta;
DE            Short=Fc-gamma RIII;
DE            Short=Fc-gamma RIIIb;
DE            Short=FcRIII;
DE            Short=FcRIIIb;
DE   AltName: Full=FcR-10;
DE   AltName: Full=IgG Fc receptor III-1;
DE   AltName: CD_antigen=CD16b;
DE   Flags: Precursor;
GN   Name=FCGR3B; Synonyms=CD16B, FCG3, FCGR3, IGFR3;
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   FCGBP_HUMAN             Reviewed;        5405 AA.
AC   Q9Y6R7; O95784;
DE   RecName: Full=IgGFc-binding protein;
DE   AltName: Full=Fcgamma-binding protein antigen;
DE            Short=FcgammaBP;
DE   Flags: Precursor;
GN   Name=FCGBP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   FCGR1_HUMAN             Reviewed;         374 AA.
AC   P12314; P12315; Q5QNW7; Q92495; Q92663;
DE   RecName: Full=High affinity immunoglobulin gamma Fc receptor I;
DE            Short=IgG Fc receptor I;
DE   AltName: Full=Fc-gamma RI;
DE            Short=FcRI;
DE   AltName: Full=Fc-gamma RIA;
DE            Short=FcgammaRIa;
DE   AltName: CD_antigen=CD64;
DE   Flags: Precursor;
GN   Name=FCGR1A; Synonyms=FCG1, FCGR1, IGFR1;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FCGRB_HUMAN             Reviewed;         280 AA.
AC   Q92637; Q7KZ13; Q92638;
DE   RecName: Full=High affinity immunoglobulin gamma Fc receptor IB;
DE            Short=IgG Fc receptor IB;
DE   AltName: Full=Fc-gamma RIB;
DE            Short=FcRIB;
DE            Short=hFcgammaRIB;
DE   Flags: Precursor;
GN   Name=FCGR1B; Synonyms=IGFRB;
DR   GO; GO:0019763; F:immunoglobulin receptor activity; NAS:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0038093; P:Fc receptor signaling pathway; NAS:GOC.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
//
ID   FCGRC_HUMAN             Reviewed;         280 AA.
AC   A6NKC4;
DE   RecName: Full=Putative high affinity immunoglobulin gamma Fc receptor IC;
DE            Short=IgG Fc receptor IC;
DE   AltName: Full=Fc-gamma RIC;
DE            Short=FcRIC;
DE            Short=hFcgammaRIC;
DE   Flags: Precursor;
GN   Name=FCGR1C; Synonyms=IGFRC;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   FCGRN_HUMAN             Reviewed;         365 AA.
AC   P55899; Q5HYM5; Q9HBV7; Q9NZ19;
DE   RecName: Full=IgG receptor FcRn large subunit p51;
DE            Short=FcRn;
DE   AltName: Full=IgG Fc fragment receptor transporter alpha chain;
DE   AltName: Full=Neonatal Fc receptor;
DE   Flags: Precursor;
GN   Name=FCGRT; Synonyms=FCRN;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0030881; F:beta-2-microglobulin binding; IBA:RefGenome.
DR   GO; GO:0019864; F:IgG binding; IDA:UniProtKB.
DR   GO; GO:0019770; F:IgG receptor activity; IBA:RefGenome.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0038094; P:Fc-gamma receptor signaling pathway; IBA:GOC.
DR   GO; GO:0002416; P:IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   FCHO1_HUMAN             Reviewed;         889 AA.
AC   O14526; A6NHE6; A8K5U5; B4E120; Q05C93; Q8IW22;
DE   RecName: Full=FCH domain only protein 1;
GN   Name=FCHO1; Synonyms=KIAA0290;
DR   GO; GO:0035612; F:AP-2 adaptor complex binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048268; P:clathrin coat assembly; IMP:UniProtKB.
DR   GO; GO:0072583; P:clathrin-mediated endocytosis; IMP:UniProtKB.
//
ID   FCHO2_HUMAN             Reviewed;         810 AA.
AC   Q0JRZ9; A8K6W7; B2RNQ9; B4DHK0; E9PG79; Q0JTJ3; Q96CF5;
DE   RecName: Full=FCH domain only protein 2;
GN   Name=FCHO2;
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048268; P:clathrin coat assembly; IMP:UniProtKB.
DR   GO; GO:0072583; P:clathrin-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0010324; P:membrane invagination; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
//
ID   FCL_HUMAN               Reviewed;         321 AA.
AC   Q13630; B2R8Y7; D3DWK5; Q567Q9; Q9UDG7;
DE   RecName: Full=GDP-L-fucose synthase;
DE            EC=1.1.1.271;
DE   AltName: Full=GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase;
DE   AltName: Full=Protein FX;
DE   AltName: Full=Red cell NADP(H)-binding protein;
DE   AltName: Full=Short-chain dehydrogenase/reductase family 4E member 1;
GN   Name=TSTA3; Synonyms=SDR4E1;
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0042356; F:GDP-4-dehydro-D-rhamnose reductase activity; TAS:UniProtKB.
DR   GO; GO:0050577; F:GDP-L-fucose synthase activity; IDA:UniProtKB.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042351; P:'de novo' GDP-L-fucose biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019835; P:cytolysis; IEA:Ensembl.
DR   GO; GO:0019673; P:GDP-mannose metabolic process; IDA:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; NAS:UniProtKB.
//
ID   FCN1_HUMAN              Reviewed;         326 AA.
AC   O00602; Q5VYV5; Q92596;
DE   RecName: Full=Ficolin-1;
DE   AltName: Full=Collagen/fibrinogen domain-containing protein 1;
DE   AltName: Full=Ficolin-A;
DE   AltName: Full=Ficolin-alpha;
DE   AltName: Full=M-ficolin;
DE   Flags: Precursor;
GN   Name=FCN1; Synonyms=FCNM;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0001867; P:complement activation, lectin pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008228; P:opsonization; TAS:ProtInc.
//
ID   FCN2_HUMAN              Reviewed;         313 AA.
AC   Q15485; A6NFG7; A8K478; Q6IS69; Q7M4P4; Q9UC57;
DE   RecName: Full=Ficolin-2;
DE   AltName: Full=37 kDa elastin-binding protein;
DE   AltName: Full=Collagen/fibrinogen domain-containing protein 2;
DE   AltName: Full=EBP-37;
DE   AltName: Full=Ficolin-B;
DE   AltName: Full=Ficolin-beta;
DE   AltName: Full=Hucolin;
DE   AltName: Full=L-ficolin;
DE   AltName: Full=Serum lectin p35;
DE   Flags: Precursor;
GN   Name=FCN2; Synonyms=FCNL;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0001867; P:complement activation, lectin pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008228; P:opsonization; TAS:ProtInc.
//
ID   FCN3_HUMAN              Reviewed;         299 AA.
AC   O75636; Q6IBJ5; Q8WW86;
DE   RecName: Full=Ficolin-3;
DE   AltName: Full=Collagen/fibrinogen domain-containing lectin 3 p35;
DE   AltName: Full=Collagen/fibrinogen domain-containing protein 3;
DE   AltName: Full=Hakata antigen;
DE   Flags: Precursor;
GN   Name=FCN3; Synonyms=FCNH, HAKA1;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0001867; P:complement activation, lectin pathway; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   FCRL1_HUMAN             Reviewed;         429 AA.
AC   Q96LA6; B2RE05; Q8N759; Q8NDI0; Q96PJ6;
DE   RecName: Full=Fc receptor-like protein 1;
DE            Short=FcR-like protein 1;
DE            Short=FcRL1;
DE   AltName: Full=Fc receptor homolog 1;
DE            Short=FcRH1;
DE   AltName: Full=IFGP family protein 1;
DE            Short=hIFGP1;
DE   AltName: Full=Immune receptor translocation-associated protein 5;
DE   AltName: CD_antigen=CD307a;
DE   Flags: Precursor;
GN   Name=FCRL1; Synonyms=FCRH1, IFGP1, IRTA5;
//
ID   FCRL2_HUMAN             Reviewed;         508 AA.
AC   Q96LA5; A0N0M5; A1L307; A6NMS0; Q6NTA1; Q9BZI4; Q9BZI5; Q9BZI6;
DE   RecName: Full=Fc receptor-like protein 2;
DE            Short=FcR-like protein 2;
DE            Short=FcRL2;
DE   AltName: Full=Fc receptor homolog 2;
DE            Short=FcRH2;
DE   AltName: Full=IFGP family protein 4;
DE   AltName: Full=Immunoglobulin receptor translocation-associated protein 4;
DE   AltName: Full=SH2 domain-containing phosphatase anchor protein 1;
DE   AltName: CD_antigen=CD307b;
DE   Flags: Precursor;
GN   Name=FCRL2; Synonyms=FCRH2, IFGP4, IRTA4, SPAP1;
GN   ORFNames=UNQ9236/PRO31998;
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IPI:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IPI:GOC.
//
ID   FCRL3_HUMAN             Reviewed;         734 AA.
AC   Q96P31; A0N0M4; A8MTH7; D3DVD2; Q5VXZ8; Q8N6S2; Q96LA4; Q96P27;
AC   Q96P28; Q96P29; Q96P30;
DE   RecName: Full=Fc receptor-like protein 3;
DE            Short=FcR-like protein 3;
DE            Short=FcRL3;
DE   AltName: Full=Fc receptor homolog 3;
DE            Short=FcRH3;
DE   AltName: Full=IFGP family protein 3;
DE            Short=hIFGP3;
DE   AltName: Full=Immune receptor translocation-associated protein 3;
DE   AltName: Full=SH2 domain-containing phosphatase anchor protein 2;
DE   AltName: CD_antigen=CD307c;
DE   Flags: Precursor;
GN   Name=FCRL3; Synonyms=FCRH3, IFGP3, IRTA3, SPAP2;
//
ID   FCRL4_HUMAN             Reviewed;         515 AA.
AC   Q96PJ5; Q96PJ3; Q96RE0;
DE   RecName: Full=Fc receptor-like protein 4;
DE            Short=FcR-like protein 4;
DE            Short=FcRL4;
DE   AltName: Full=Fc receptor homolog 4;
DE            Short=FcRH4;
DE   AltName: Full=IFGP family protein 2;
DE            Short=hIFGP2;
DE   AltName: Full=Immune receptor translocation-associated protein 1;
DE   AltName: CD_antigen=CD307d;
DE   Flags: Precursor;
GN   Name=FCRL4; Synonyms=FCRH4, IFGP2, IRTA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   FCRL5_HUMAN             Reviewed;         977 AA.
AC   Q96RD9; A0N0M2; B7WNT9; B7WP94; Q495Q2; Q495Q4; Q5VYK9; Q6UY46;
DE   RecName: Full=Fc receptor-like protein 5;
DE            Short=FcR-like protein 5;
DE            Short=FcRL5;
DE   AltName: Full=BXMAS1;
DE   AltName: Full=Fc receptor homolog 5;
DE            Short=FcRH5;
DE   AltName: Full=Immune receptor translocation-associated protein 2;
DE   AltName: CD_antigen=CD307e;
DE   Flags: Precursor;
GN   Name=FCRL5; Synonyms=FCRH5, IRTA2; ORFNames=UNQ503/PRO820;
//
ID   FCRL6_HUMAN             Reviewed;         434 AA.
AC   Q6DN72; A1KXW6; A2A4D6; Q6DN73; Q6XRC3; Q6ZNI1;
DE   RecName: Full=Fc receptor-like protein 6;
DE            Short=FcR-like protein 6;
DE            Short=FcRL6;
DE   AltName: Full=Fc receptor homolog 6;
DE            Short=FcRH6;
DE   AltName: Full=IFGP6;
DE   Flags: Precursor;
GN   Name=FCRL6; Synonyms=FCRH6;
//
ID   FCRLA_HUMAN             Reviewed;         359 AA.
AC   Q7L513; A0N0M1; Q5VXA1; Q5VXA2; Q5VXA3; Q5VXA4; Q5VXB0; Q8NEW4;
AC   Q8WXH3; Q96PC6; Q96PJ0; Q96PJ1; Q96PJ2; Q96PJ4; Q9BR57;
DE   RecName: Full=Fc receptor-like A;
DE   AltName: Full=Fc receptor homolog expressed in B-cells;
DE   AltName: Full=Fc receptor-like and mucin-like protein 1;
DE   AltName: Full=Fc receptor-like protein;
DE   AltName: Full=Fc receptor-related protein X;
DE            Short=FcRX;
DE   Flags: Precursor;
GN   Name=FCRLA; Synonyms=FCRL, FCRL1, FCRLM1, FCRX, FREB;
GN   ORFNames=UNQ291/PRO329;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   FCRLB_HUMAN             Reviewed;         426 AA.
AC   Q6BAA4; A2A3J5; A2A3J7; Q5VXA6; Q6BAA0; Q6BAA1; Q6BAA2; Q6BAA3;
AC   Q8IXZ7;
DE   RecName: Full=Fc receptor-like B;
DE   AltName: Full=Fc receptor homolog expressed in B-cells protein 2;
DE            Short=FREB-2;
DE   AltName: Full=Fc receptor-like and mucin-like protein 2;
DE   AltName: Full=Fc receptor-like protein 2;
DE   AltName: Full=Fc receptor-related protein Y;
DE            Short=FcRY;
DE   Flags: Precursor;
GN   Name=FCRLB; Synonyms=FCRL2, FCRLM2, FCRY, FREB2;
//
ID   FCSD1_HUMAN             Reviewed;         690 AA.
AC   Q86WN1; Q6UX75; Q86Y77; Q9NXX8;
DE   RecName: Full=FCH and double SH3 domains protein 1;
GN   Name=FCHSD1; ORFNames=UNQ737/PRO1431;
//
ID   FCSD2_HUMAN             Reviewed;         740 AA.
AC   O94868; B4DNI3; Q7L8J9; Q8WVM2; Q96FV7; Q9UF77;
DE   RecName: Full=FCH and double SH3 domains protein 2;
DE   AltName: Full=Carom;
DE   AltName: Full=SH3 multiple domains protein 3;
GN   Name=FCHSD2; Synonyms=KIAA0769, SH3MD3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FDFT_HUMAN              Reviewed;         417 AA.
AC   P37268; Q96GT0;
DE   RecName: Full=Squalene synthase;
DE            Short=SQS;
DE            Short=SS;
DE            EC=2.5.1.21;
DE   AltName: Full=FPP:FPP farnesyltransferase;
DE   AltName: Full=Farnesyl-diphosphate farnesyltransferase;
GN   Name=FDFT1;
DR   GuidetoPHARMACOLOGY; 645; -.
DR   GO; GO:0004310; F:farnesyl-diphosphate farnesyltransferase activity; TAS:Reactome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051996; F:squalene synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0045338; P:farnesyl diphosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
//
ID   FDSCP_HUMAN             Reviewed;          85 AA.
AC   Q8NFU4;
DE   RecName: Full=Follicular dendritic cell secreted peptide;
DE            Short=FDC secreted protein;
DE            Short=FDC-SP;
DE   Flags: Precursor;
GN   Name=FDCSP; Synonyms=C4orf7; ORFNames=UNQ733/PRO1419;
//
ID   FDXA1_HUMAN             Reviewed;         624 AA.
AC   Q9BRP7; A0PJW7;
DE   RecName: Full=Ferredoxin-fold anticodon-binding domain-containing protein 1;
DE            Short=FDX-ACDB domain-containing protein 1;
GN   Name=FDXACB1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR   GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:InterPro.
//
ID   FEAS1_HUMAN             Reviewed;         138 AA.
AC   Q8NA97; B2RPB9;
DE   RecName: Full=Putative uncharacterized protein FER1L6-AS1;
DE   AltName: Full=FER1L6 antisense RNA 1;
DE   AltName: Full=FER1L6 antisense gene protein 1;
GN   Name=FER1L6-AS1; Synonyms=C8orf54;
//
ID   FEAS2_HUMAN             Reviewed;         137 AA.
AC   Q96M78;
DE   RecName: Full=Putative uncharacterized protein encoded by FER1L6-AS2;
DE   AltName: Full=FER1L6 antisense RNA 2;
DE   AltName: Full=FER1L6 antisense gene protein 2;
GN   Name=FER1L6-AS2; Synonyms=C8orf78;
//
ID   FEM1A_HUMAN             Reviewed;         669 AA.
AC   Q9BSK4; B2RDI3; Q711P8; Q9NPN7; Q9NPW8;
DE   RecName: Full=Protein fem-1 homolog A;
DE            Short=FEM1a;
DE   AltName: Full=FEM1-alpha;
DE   AltName: Full=Prostaglandin E receptor 4-associated protein;
GN   Name=FEM1A; Synonyms=EPRAP;
DR   GO; GO:0031867; F:EP4 subtype prostaglandin E2 receptor binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.
//
ID   FEM1B_HUMAN             Reviewed;         627 AA.
AC   Q9UK73; O43146;
DE   RecName: Full=Protein fem-1 homolog B;
DE            Short=FEM1b;
DE   AltName: Full=FEM1-beta;
DE   AltName: Full=Fem-1-like death receptor-binding protein alpha;
DE   AltName: Full=Fem-1-like in apoptotic pathway protein alpha;
DE            Short=F1A-alpha;
GN   Name=FEM1B; Synonyms=F1AA, KIAA0396;
DR   GO; GO:0005123; F:death receptor binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0060442; P:branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0060743; P:epithelial cell maturation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:2000001; P:regulation of DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:1902041; P:regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:0051438; P:regulation of ubiquitin-protein ligase activity; IMP:UniProtKB.
//
ID   FEM1C_HUMAN             Reviewed;         617 AA.
AC   Q96JP0; B2RE47; Q8N3V8; Q9H704; Q9NPL6; Q9NPL9;
DE   RecName: Full=Protein fem-1 homolog C;
DE            Short=FEM1c;
DE   AltName: Full=FEM1-gamma;
GN   Name=FEM1C; Synonyms=KIAA1785;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   FEN1_HUMAN              Reviewed;         380 AA.
AC   P39748;
DE   RecName: Full=Flap endonuclease 1;
DE            Short=FEN-1;
DE            EC=3.1.-.-;
DE   AltName: Full=DNase IV;
DE   AltName: Full=Flap structure-specific endonuclease 1;
DE   AltName: Full=Maturation factor 1;
DE            Short=MF1;
DE            Short=hFEN-1;
GN   Name=FEN1; Synonyms=RAD2;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0008309; F:double-stranded DNA exodeoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0004519; F:endonuclease activity; TAS:ProtInc.
DR   GO; GO:0004527; F:exonuclease activity; TAS:ProtInc.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; TAS:GOC.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0043137; P:DNA replication, removal of RNA primer; IDA:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:ProtInc.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0009650; P:UV protection; TAS:ProtInc.
//
ID   FER3L_HUMAN             Reviewed;         166 AA.
AC   Q96RJ6; Q495K0;
DE   RecName: Full=Fer3-like protein;
DE   AltName: Full=Basic helix-loop-helix protein N-twist;
DE   AltName: Full=Class A basic helix-loop-helix protein 31;
DE            Short=bHLHa31;
DE   AltName: Full=Nephew of atonal 3;
DE   AltName: Full=Neuronal twist;
GN   Name=FERD3L; Synonyms=BHLHA31, NATO3, NTWIST;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0033504; P:floor plate development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0050767; P:regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FERM1_HUMAN             Reviewed;         677 AA.
AC   Q9BQL6; D3DW10; Q8IX34; Q8IYH2; Q9NWM2; Q9NXQ3;
DE   RecName: Full=Fermitin family homolog 1;
DE   AltName: Full=Kindlerin;
DE   AltName: Full=Kindlin syndrome protein;
DE   AltName: Full=Kindlin-1;
DE   AltName: Full=Unc-112-related protein 1;
GN   Name=FERMT1; Synonyms=C20orf42, KIND1, URP1;
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IDA:UniProtKB.
DR   GO; GO:0051546; P:keratinocyte migration; IDA:UniProtKB.
DR   GO; GO:0043616; P:keratinocyte proliferation; IDA:UniProtKB.
//
ID   FERM2_HUMAN             Reviewed;         680 AA.
AC   Q96AC1; B5TJY2; Q14840; Q86TY7;
DE   RecName: Full=Fermitin family homolog 2;
DE   AltName: Full=Kindlin-2;
DE   AltName: Full=Mitogen-inducible gene 2 protein;
DE            Short=MIG-2;
DE   AltName: Full=Pleckstrin homology domain-containing family C member 1;
DE            Short=PH domain-containing family C member 1;
GN   Name=FERMT2; Synonyms=KIND2, MIG2, PLEKHC1;
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0033622; P:integrin activation; IMP:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0072657; P:protein localization to membrane; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:UniProtKB.
//
ID   FER_HUMAN               Reviewed;         822 AA.
AC   P16591; B2RCR4; B4DSQ2; H2FLB8;
DE   RecName: Full=Tyrosine-protein kinase Fer;
DE            EC=2.7.10.2;
DE   AltName: Full=Feline encephalitis virus-related kinase FER;
DE   AltName: Full=Fujinami poultry sarcoma/Feline sarcoma-related protein Fer;
DE   AltName: Full=Proto-oncogene c-Fer;
DE   AltName: Full=Tyrosine kinase 3;
DE   AltName: Full=p94-Fer;
GN   Name=FER; Synonyms=TYK3;
DR   GuidetoPHARMACOLOGY; 2022; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0044331; P:cell-cell adhesion mediated by cadherin; ISS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IMP:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0050904; P:diapedesis; ISS:UniProtKB.
DR   GO; GO:0035426; P:extracellular matrix-cell signaling; ISS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038028; P:insulin receptor signaling pathway via phosphatidylinositol 3-kinase; ISS:UniProtKB.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0038109; P:Kit signaling pathway; ISS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0033007; P:negative regulation of mast cell activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0010762; P:regulation of fibroblast migration; IEA:Ensembl.
DR   GO; GO:0010591; P:regulation of lamellipodium assembly; IDA:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0036119; P:response to platelet-derived growth factor; ISS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.
//
ID   FES_HUMAN               Reviewed;         822 AA.
AC   P07332; B2R6E6; B4DUD0; E9PC94; E9PC95; Q2VXS7; Q2VXS8; Q2VXT0;
AC   Q6GTU5;
DE   RecName: Full=Tyrosine-protein kinase Fes/Fps;
DE            EC=2.7.10.2;
DE   AltName: Full=Feline sarcoma/Fujinami avian sarcoma oncogene homolog;
DE   AltName: Full=Proto-oncogene c-Fes;
DE   AltName: Full=Proto-oncogene c-Fps;
DE   AltName: Full=p93c-fes;
GN   Name=FES; Synonyms=FPS;
DR   GuidetoPHARMACOLOGY; 2023; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IDA:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IMP:UniProtKB.
DR   GO; GO:0045639; P:positive regulation of myeloid cell differentiation; IMP:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0030155; P:regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; IMP:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.
DR   GO; GO:0060627; P:regulation of vesicle-mediated transport; TAS:UniProtKB.
//
ID   FETA_HUMAN              Reviewed;         609 AA.
AC   P02771; B2RBU3;
DE   RecName: Full=Alpha-fetoprotein;
DE   AltName: Full=Alpha-1-fetoprotein;
DE   AltName: Full=Alpha-fetoglobulin;
DE   Flags: Precursor;
GN   Name=AFP; Synonyms=HPAFP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0042448; P:progesterone metabolic process; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   FETUA_HUMAN             Reviewed;         367 AA.
AC   P02765; A8K9N6; B2R7G1; O14961; O14962; Q9P152;
DE   RecName: Full=Alpha-2-HS-glycoprotein;
DE   AltName: Full=Alpha-2-Z-globulin;
DE   AltName: Full=Ba-alpha-2-glycoprotein;
DE   AltName: Full=Fetuin-A;
DE   Contains:
DE     RecName: Full=Alpha-2-HS-glycoprotein chain A;
DE   Contains:
DE     RecName: Full=Alpha-2-HS-glycoprotein chain B;
DE   Flags: Precursor;
GN   Name=AHSG; Synonyms=FETUA; ORFNames=PRO2743;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0019210; F:kinase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IDA:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; NAS:GOC.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0006907; P:pinocytosis; NAS:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0030500; P:regulation of bone mineralization; NAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; NAS:UniProtKB.
//
ID   FETUB_HUMAN             Reviewed;         382 AA.
AC   Q9UGM5; B2RCW6; E9PG06; Q1RMZ0; Q5J876; Q6DK58; Q6GRB6; Q9Y6Z0;
DE   RecName: Full=Fetuin-B;
DE   AltName: Full=16G2;
DE   AltName: Full=Fetuin-like protein IRL685;
DE   AltName: Full=Gugu;
DE   Flags: Precursor;
GN   Name=FETUB;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; ISS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; ISS:UniProtKB.
//
ID   FEV_HUMAN               Reviewed;         238 AA.
AC   Q99581;
DE   RecName: Full=Protein FEV;
DE   AltName: Full=Fifth Ewing variant protein;
DE   AltName: Full=PC12 ETS domain-containing transcription factor 1;
DE            Short=PC12 ETS factor 1;
DE            Short=Pet-1;
GN   Name=FEV; Synonyms=PET1;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   FEZ1_HUMAN              Reviewed;         392 AA.
AC   Q99689; O00679; O00728; Q6IBI7;
DE   RecName: Full=Fasciculation and elongation protein zeta-1;
DE   AltName: Full=Zygin I;
DE   AltName: Full=Zygin-1;
GN   Name=FEZ1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0051654; P:establishment of mitochondrion localization; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   FEZ2_HUMAN              Reviewed;         353 AA.
AC   Q9UHY8; Q5EBN3; Q76LN0; Q99690;
DE   RecName: Full=Fasciculation and elongation protein zeta-2;
DE   AltName: Full=Zygin II;
DE   AltName: Full=Zygin-2;
GN   Name=FEZ2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FEZF1_HUMAN             Reviewed;         475 AA.
AC   A0PJY2; A0PJY3; A4D0W3; B4DUP9; B7ZM98;
DE   RecName: Full=Fez family zinc finger protein 1;
DE   AltName: Full=Zinc finger protein 312B;
GN   Name=FEZF1; Synonyms=FEZ, ZNF312B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FEZF2_HUMAN             Reviewed;         459 AA.
AC   Q8TBJ5; A8K349; Q9BZ91; Q9NWB9;
DE   RecName: Full=Fez family zinc finger protein 2;
DE   AltName: Full=Forebrain embryonic zinc finger-like protein 2;
DE   AltName: Full=Zinc finger protein 312;
DE   AltName: Full=Zinc finger protein Fez-like;
GN   Name=FEZF2; Synonyms=FEZL, ZNF312; ORFNames=FKSG36;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0021853; P:cerebral cortex GABAergic interneuron migration; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FFAR1_HUMAN             Reviewed;         300 AA.
AC   O14842; Q0VAS2; Q4VBL4;
DE   RecName: Full=Free fatty acid receptor 1;
DE   AltName: Full=G-protein coupled receptor 40;
GN   Name=FFAR1; Synonyms=GPR40;
DR   GuidetoPHARMACOLOGY; 225; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FFAR2_HUMAN             Reviewed;         330 AA.
AC   O15552; B0M0J9; Q4VAZ3; Q4VAZ5; Q4VBL5;
DE   RecName: Full=Free fatty acid receptor 2;
DE   AltName: Full=G-protein coupled receptor 43;
GN   Name=FFAR2; Synonyms=GPR43;
DR   GuidetoPHARMACOLOGY; 226; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   FFAR3_HUMAN             Reviewed;         346 AA.
AC   O14843; B2RWM8; Q14CM7;
DE   RecName: Full=Free fatty acid receptor 3;
DE   AltName: Full=G-protein coupled receptor 41;
GN   Name=FFAR3; Synonyms=GPR41;
DR   GuidetoPHARMACOLOGY; 227; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   FFAR4_HUMAN             Reviewed;         377 AA.
AC   Q5NUL3; Q495H1; Q5VY25; Q5VY26; Q7Z605; Q86SM7;
DE   RecName: Full=Free fatty acid receptor 4;
DE   AltName: Full=G-protein coupled receptor 120;
DE   AltName: Full=G-protein coupled receptor 129;
DE   AltName: Full=G-protein coupled receptor GT01;
DE   AltName: Full=G-protein coupled receptor PGR4;
DE   AltName: Full=Omega-3 fatty acid receptor 1;
GN   Name=FFAR4; Synonyms=GPR120, GPR129, O3FAR1, PGR4;
DR   GuidetoPHARMACOLOGY; 127; -.
DR   GO; GO:0005504; F:fatty acid binding; ISS:UniProtKB.
DR   GO; GO:0008527; F:taste receptor activity; IEA:Ensembl.
DR   GO; GO:0046879; P:hormone secretion; IEA:Ensembl.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0010827; P:regulation of glucose transport; ISS:UniProtKB.
//
ID   FGD1_HUMAN              Reviewed;         961 AA.
AC   P98174; Q5H999; Q8N4D9;
DE   RecName: Full=FYVE, RhoGEF and PH domain-containing protein 1;
DE   AltName: Full=Faciogenital dysplasia 1 protein;
DE   AltName: Full=Rho/Rac guanine nucleotide exchange factor FGD1;
DE            Short=Rho/Rac GEF;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 3;
GN   Name=FGD1; Synonyms=FGDY, ZFYVE3;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   FGD2_HUMAN              Reviewed;         655 AA.
AC   Q7Z6J4; Q5T8I1; Q6P6A8; Q6ZNL5; Q8IZ32; Q8N868; Q9H7M2;
DE   RecName: Full=FYVE, RhoGEF and PH domain-containing protein 2;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 4;
GN   Name=FGD2; Synonyms=ZFYVE4;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   FGD3_HUMAN              Reviewed;         725 AA.
AC   Q5JSP0; Q4VX84; Q7Z7D9; Q8N5G1;
DE   RecName: Full=FYVE, RhoGEF and PH domain-containing protein 3;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 5;
GN   Name=FGD3; Synonyms=ZFYVE5;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   FGD4_HUMAN              Reviewed;         766 AA.
AC   Q96M96; Q6ULS2; Q8TCP6;
DE   RecName: Full=FYVE, RhoGEF and PH domain-containing protein 4;
DE   AltName: Full=Actin filament-binding protein frabin;
DE   AltName: Full=FGD1-related F-actin-binding protein;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 6;
GN   Name=FGD4; Synonyms=FRABP, ZFYVE6;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0030035; P:microspike assembly; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   FGD5_HUMAN              Reviewed;        1462 AA.
AC   Q6ZNL6; B3KVQ3; Q6MZY1; Q7Z303; Q8IYP3; Q8N861; Q8N8G4;
DE   RecName: Full=FYVE, RhoGEF and PH domain-containing protein 5;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 23;
GN   Name=FGD5; Synonyms=ZFYVE23;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
//
ID   FGD6_HUMAN              Reviewed;        1430 AA.
AC   Q6ZV73; Q6ZR53; Q7Z2Z7; Q96D44; Q9NUR8; Q9P2I5;
DE   RecName: Full=FYVE, RhoGEF and PH domain-containing protein 6;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 24;
GN   Name=FGD6; Synonyms=KIAA1362, ZFYVE24;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
//
ID   FGF12_HUMAN             Reviewed;         243 AA.
AC   P61328; B2R6B7; B2R976; O35339; P70376; Q8TBG5; Q92912; Q93001;
DE   RecName: Full=Fibroblast growth factor 12;
DE            Short=FGF-12;
DE   AltName: Full=Fibroblast growth factor homologous factor 1;
DE            Short=FHF-1;
DE   AltName: Full=Myocyte-activating factor;
GN   Name=FGF12; Synonyms=FGF12B, FHF1;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; NAS:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; IPI:MGI.
DR   GO; GO:2001258; P:negative regulation of cation channel activity; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0003254; P:regulation of membrane depolarization; IEA:Ensembl.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   FGF11_HUMAN             Reviewed;         225 AA.
AC   Q92914; Q2YDX8;
DE   RecName: Full=Fibroblast growth factor 11;
DE            Short=FGF-11;
DE   AltName: Full=Fibroblast growth factor homologous factor 3;
DE            Short=FHF-3;
GN   Name=FGF11; Synonyms=FHF3;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF16_HUMAN             Reviewed;         207 AA.
AC   O43320;
DE   RecName: Full=Fibroblast growth factor 16;
DE            Short=FGF-16;
GN   Name=FGF16;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0009266; P:response to temperature stimulus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF17_HUMAN             Reviewed;         216 AA.
AC   O60258; B7ZLG4; Q2M2W1;
DE   RecName: Full=Fibroblast growth factor 17;
DE            Short=FGF-17;
DE   Flags: Precursor;
GN   Name=FGF17; ORFNames=UNQ161/PRO187;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005105; F:type 1 fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0005111; F:type 2 fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF13_HUMAN             Reviewed;         245 AA.
AC   Q92913; B1AK18; B7Z4M7; B7Z8N0; D3DWH4; O95830; Q9NZH9; Q9NZI0;
DE   RecName: Full=Fibroblast growth factor 13;
DE            Short=FGF-13;
DE   AltName: Full=Fibroblast growth factor homologous factor 2;
DE            Short=FHF-2;
GN   Name=FGF13; Synonyms=FHF2;
DR   GO; GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0044325; F:ion channel binding; ISS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IGI:MGI.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB.
DR   GO; GO:0045200; P:establishment of neuroblast polarity; ISS:UniProtKB.
DR   GO; GO:0021766; P:hippocampus development; ISS:UniProtKB.
DR   GO; GO:0007612; P:learning; ISS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:MGI.
DR   GO; GO:0007613; P:memory; ISS:UniProtKB.
DR   GO; GO:0046785; P:microtubule polymerization; ISS:UniProtKB.
DR   GO; GO:0048671; P:negative regulation of collateral sprouting; ISS:UniProtKB.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IGI:GOC.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF10_HUMAN             Reviewed;         208 AA.
AC   O15520; Q6FHT6; Q96P59;
DE   RecName: Full=Fibroblast growth factor 10;
DE            Short=FGF-10;
DE   AltName: Full=Keratinocyte growth factor 2;
DE   Flags: Precursor;
GN   Name=FGF10;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0005111; F:type 2 fibroblast growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0060667; P:branch elongation involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IDA:UniProtKB.
DR   GO; GO:0060436; P:bronchiole morphogenesis; IEA:Ensembl.
DR   GO; GO:0060447; P:bud outgrowth involved in lung branching; IDA:MGI.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0030538; P:embryonic genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010631; P:epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0050673; P:epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048807; P:female genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; IDA:MGI.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0070384; P:Harderian gland development; IEA:Ensembl.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0032808; P:lacrimal gland development; IMP:UniProtKB.
DR   GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
DR   GO; GO:0060428; P:lung epithelium development; IDA:MGI.
DR   GO; GO:0061115; P:lung proximal/distal axis specification; IEA:Ensembl.
DR   GO; GO:0060430; P:lung saccule development; IMP:UniProtKB.
DR   GO; GO:0048808; P:male genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0060615; P:mammary gland bud formation; IEA:Ensembl.
DR   GO; GO:0060915; P:mesenchymal cell differentiation involved in lung development; IEA:Ensembl.
DR   GO; GO:0060496; P:mesenchymal-epithelial cell signaling involved in lung development; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; IEP:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; IEP:UniProtKB.
DR   GO; GO:0003338; P:metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0042693; P:muscle cell fate commitment; IEA:Ensembl.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0030916; P:otic vesicle formation; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IMP:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060054; P:positive regulation of epithelial cell proliferation involved in wound healing; NAS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0071338; P:positive regulation of hair follicle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051549; P:positive regulation of keratinocyte migration; IDA:UniProtKB.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0050671; P:positive regulation of lymphocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050677; P:positive regulation of urothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0070352; P:positive regulation of white fat cell proliferation; IEA:Ensembl.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0060019; P:radial glial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032925; P:regulation of activin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060665; P:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; IEA:Ensembl.
DR   GO; GO:0060685; P:regulation of prostatic bud formation; IEA:Ensembl.
DR   GO; GO:0046877; P:regulation of saliva secretion; IMP:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007431; P:salivary gland development; IMP:UniProtKB.
DR   GO; GO:0061033; P:secretion by lung epithelial cell involved in lung growth; IDA:UniProtKB.
DR   GO; GO:0060879; P:semicircular canal fusion; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0060661; P:submandibular salivary gland formation; IEA:Ensembl.
DR   GO; GO:0070075; P:tear secretion; IMP:UniProtKB.
DR   GO; GO:0048538; P:thymus development; IDA:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
DR   GO; GO:0060510; P:Type II pneumocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050674; P:urothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050872; P:white fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IDA:UniProtKB.
//
ID   FGF14_HUMAN             Reviewed;         247 AA.
AC   Q92915; Q86YN7; Q96QX6;
DE   RecName: Full=Fibroblast growth factor 14;
DE            Short=FGF-14;
DE   AltName: Full=Fibroblast growth factor homologous factor 4;
DE            Short=FHF-4;
GN   Name=FGF14; Synonyms=FHF4;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; IPI:MGI.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   FGF19_HUMAN             Reviewed;         216 AA.
AC   O95750;
DE   RecName: Full=Fibroblast growth factor 19;
DE            Short=FGF-19;
DE   Flags: Precursor;
GN   Name=FGF19; ORFNames=UNQ334/PRO533;
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070858; P:negative regulation of bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
//
ID   FGF18_HUMAN             Reviewed;         207 AA.
AC   O76093; D3DQL7; Q6UWF1;
DE   RecName: Full=Fibroblast growth factor 18;
DE            Short=FGF-18;
DE   AltName: Full=zFGF5;
DE   Flags: Precursor;
GN   Name=FGF18; ORFNames=UNQ420/PRO856;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005105; F:type 1 fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0005111; F:type 2 fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001957; P:intramembranous ossification; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF1_HUMAN              Reviewed;         155 AA.
AC   P05230; B2R5T0; D3DQF2; P07502; Q16588;
DE   RecName: Full=Fibroblast growth factor 1;
DE            Short=FGF-1;
DE   AltName: Full=Acidic fibroblast growth factor;
DE            Short=aFGF;
DE   AltName: Full=Endothelial cell growth factor;
DE            Short=ECGF;
DE   AltName: Full=Heparin-binding growth factor 1;
DE            Short=HBGF-1;
DE   Flags: Precursor;
GN   Name=FGF1; Synonyms=FGFA;
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IPI:MGI.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0060681; P:branch elongation involved in ureteric bud branching; IDA:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0072163; P:mesonephric epithelium development; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0045542; P:positive regulation of cholesterol biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:1902533; P:positive regulation of intracellular signal transduction; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   FGF20_HUMAN             Reviewed;         211 AA.
AC   Q9NP95; B2RPH5;
DE   RecName: Full=Fibroblast growth factor 20;
DE            Short=FGF-20;
GN   Name=FGF20;
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060113; P:inner ear receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0060043; P:regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF22_HUMAN             Reviewed;         170 AA.
AC   Q9HCT0; B2RPH4;
DE   RecName: Full=Fibroblast growth factor 22;
DE            Short=FGF-22;
DE   Flags: Precursor;
GN   Name=FGF22; ORFNames=UNQ2500/PRO5800;
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
//
ID   FGF23_HUMAN             Reviewed;         251 AA.
AC   Q9GZV9; Q4V758;
DE   RecName: Full=Fibroblast growth factor 23;
DE            Short=FGF-23;
DE   AltName: Full=Phosphatonin;
DE   AltName: Full=Tumor-derived hypophosphatemia-inducing factor;
DE   Contains:
DE     RecName: Full=Fibroblast growth factor 23 N-terminal peptide;
DE   Contains:
DE     RecName: Full=Fibroblast growth factor 23 C-terminal peptide;
DE   Flags: Precursor;
GN   Name=FGF23; Synonyms=HYPF; ORFNames=UNQ3027/PRO9828;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; ISS:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055062; P:phosphate ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0090080; P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:UniProtKB.
DR   GO; GO:0010966; P:regulation of phosphate transport; IDA:UniProtKB.
DR   GO; GO:0042369; P:vitamin D catabolic process; IDA:UniProtKB.
//
ID   FGF21_HUMAN             Reviewed;         209 AA.
AC   Q9NSA1; Q8N683;
DE   RecName: Full=Fibroblast growth factor 21;
DE            Short=FGF-21;
DE   Flags: Precursor;
GN   Name=FGF21; ORFNames=UNQ3115/PRO10196;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:UniProtKB.
DR   GO; GO:0045716; P:positive regulation of low-density lipoprotein particle receptor biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0090080; P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010988; P:regulation of low-density lipoprotein particle clearance; NAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF2_HUMAN              Reviewed;         288 AA.
AC   P09038; A4LBB8; O00527; P78443; Q16443; Q5PY50; Q7KZ11; Q7KZ72;
AC   Q9UC54; Q9UCS5; Q9UCS6;
DE   RecName: Full=Fibroblast growth factor 2;
DE            Short=FGF-2;
DE   AltName: Full=Basic fibroblast growth factor;
DE            Short=bFGF;
DE   AltName: Full=Heparin-binding growth factor 2;
DE            Short=HBGF-2;
DE   Flags: Precursor;
GN   Name=FGF2; Synonyms=FGFB;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IPI:MGI.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IDA:UniProtKB.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0060591; P:chondroblast differentiation; IDA:UniProtKB.
DR   GO; GO:0060128; P:corticotropin hormone secreting cell differentiation; IEA:Ensembl.
DR   GO; GO:0048598; P:embryonic morphogenesis; TAS:DFLAT.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030214; P:hyaluronan catabolic process; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032958; P:inositol phosphate biosynthetic process; IDA:DFLAT.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0000189; P:MAPK import into nucleus; IEA:Ensembl.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010764; P:negative regulation of fibroblast migration; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0061045; P:negative regulation of wound healing; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:DFLAT.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0042660; P:positive regulation of cell fate specification; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0021940; P:positive regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:DFLAT.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; IDA:DFLAT.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0045765; P:regulation of angiogenesis; TAS:DFLAT.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0046668; P:regulation of retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:DFLAT.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0048864; P:stem cell development; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEA:Ensembl.
DR   GO; GO:0060129; P:thyroid-stimulating hormone-secreting cell differentiation; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; TAS:DFLAT.
//
ID   FGF3_HUMAN              Reviewed;         239 AA.
AC   P11487; Q0VG69;
DE   RecName: Full=Fibroblast growth factor 3;
DE            Short=FGF-3;
DE   AltName: Full=Heparin-binding growth factor 3;
DE            Short=HBGF-3;
DE   AltName: Full=Proto-oncogene Int-2;
DE   Flags: Precursor;
GN   Name=FGF3; Synonyms=INT2;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055026; P:negative regulation of cardiac muscle tissue development; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0030916; P:otic vesicle formation; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   FGF4_HUMAN              Reviewed;         206 AA.
AC   P08620; B7U994;
DE   RecName: Full=Fibroblast growth factor 4;
DE            Short=FGF-4;
DE   AltName: Full=Heparin secretory-transforming protein 1;
DE            Short=HST;
DE            Short=HST-1;
DE            Short=HSTF-1;
DE   AltName: Full=Heparin-binding growth factor 4;
DE            Short=HBGF-4;
DE   AltName: Full=Transforming protein KS3;
DE   Flags: Precursor;
GN   Name=FGF4; Synonyms=HST, HSTF1, KS3;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0060591; P:chondroblast differentiation; IDA:UniProtKB.
DR   GO; GO:0060363; P:cranial suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010463; P:mesenchymal cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   FGF5_HUMAN              Reviewed;         268 AA.
AC   P12034; B2R554; O75846; Q3Y8M3; Q8NF90;
DE   RecName: Full=Fibroblast growth factor 5;
DE            Short=FGF-5;
DE   AltName: Full=Heparin-binding growth factor 5;
DE            Short=HBGF-5;
DE   AltName: Full=Smag-82;
DE   Flags: Precursor;
GN   Name=FGF5;
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IDA:MGI.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:MGI.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
//
ID   FGF6_HUMAN              Reviewed;         208 AA.
AC   P10767; Q0VAE1;
DE   RecName: Full=Fibroblast growth factor 6;
DE            Short=FGF-6;
DE   AltName: Full=Heparin secretory-transforming protein 2;
DE            Short=HST-2;
DE            Short=HSTF-2;
DE   AltName: Full=Heparin-binding growth factor 6;
DE            Short=HBGF-6;
DE   Flags: Precursor;
GN   Name=FGF6; Synonyms=HST2, HSTF2;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FGF7_HUMAN              Reviewed;         194 AA.
AC   P21781;
DE   RecName: Full=Fibroblast growth factor 7;
DE            Short=FGF-7;
DE   AltName: Full=Heparin-binding growth factor 7;
DE            Short=HBGF-7;
DE   AltName: Full=Keratinocyte growth factor;
DE   Flags: Precursor;
GN   Name=FGF7; Synonyms=KGF;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010463; P:mesenchymal cell proliferation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IDA:MGI.
DR   GO; GO:0051549; P:positive regulation of keratinocyte migration; IDA:UniProtKB.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0060665; P:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0061033; P:secretion by lung epithelial cell involved in lung growth; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   FGF8_HUMAN              Reviewed;         233 AA.
AC   P55075; A1A514; Q14915; Q15766;
DE   RecName: Full=Fibroblast growth factor 8;
DE            Short=FGF-8;
DE   AltName: Full=Androgen-induced growth factor;
DE            Short=AIGF;
DE   AltName: Full=Heparin-binding growth factor 8;
DE            Short=HBGF-8;
DE   Flags: Precursor;
GN   Name=FGF8; Synonyms=AIGF;
DR   GO; GO:0042056; F:chemoattractant activity; IEA:Ensembl.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0005105; F:type 1 fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0005111; F:type 2 fibroblast growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; NAS:UniProtKB.
DR   GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0060348; P:bone development; IMP:UniProtKB.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0090134; P:cell migration involved in mesendoderm migration; IEA:Ensembl.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0060128; P:corticotropin hormone secreting cell differentiation; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IDA:UniProtKB.
DR   GO; GO:0033563; P:dorsal/ventral axon guidance; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0021798; P:forebrain dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0007369; P:gastrulation; NAS:UniProtKB.
DR   GO; GO:0008406; P:gonad development; IMP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060425; P:lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0008078; P:mesodermal cell migration; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; IEP:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; IEP:UniProtKB.
DR   GO; GO:0030917; P:midbrain-hindbrain boundary development; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0055026; P:negative regulation of cardiac muscle tissue development; IMP:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0001839; P:neural plate morphogenesis; IEA:Ensembl.
DR   GO; GO:0060563; P:neuroepithelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042476; P:odontogenesis; IEP:UniProtKB.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0030916; P:otic vesicle formation; IEA:Ensembl.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021543; P:pallium development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0021544; P:subpallium development; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0060129; P:thyroid-stimulating hormone-secreting cell differentiation; IEA:Ensembl.
//
ID   FGFP1_HUMAN             Reviewed;         234 AA.
AC   Q14512; A8K5J2;
DE   RecName: Full=Fibroblast growth factor-binding protein 1;
DE            Short=FGF-BP;
DE            Short=FGF-BP1;
DE            Short=FGF-binding protein 1;
DE            Short=FGFBP-1;
DE   AltName: Full=17 kDa heparin-binding growth factor-binding protein;
DE            Short=17 kDa HBGF-binding protein;
DE            Short=HBp17;
DE   Flags: Precursor;
GN   Name=FGFBP1; Synonyms=FGFBP, HBP17;
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   FGF9_HUMAN              Reviewed;         208 AA.
AC   P31371; A8K427; Q3SY32;
DE   RecName: Full=Fibroblast growth factor 9;
DE            Short=FGF-9;
DE   AltName: Full=Glia-activating factor;
DE            Short=GAF;
DE   AltName: Full=Heparin-binding growth factor 9;
DE            Short=HBGF-9;
DE   Flags: Precursor;
GN   Name=FGF9;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0048505; P:regulation of timing of cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   FGFP2_HUMAN             Reviewed;         223 AA.
AC   Q9BYJ0;
DE   RecName: Full=Fibroblast growth factor-binding protein 2;
DE            Short=FGF-BP2;
DE            Short=FGF-binding protein 2;
DE            Short=FGFBP-2;
DE   AltName: Full=37 kDa killer-specific secretory protein;
DE            Short=Ksp37;
DE   AltName: Full=HBp17-related protein;
DE            Short=HBp17-RP;
DE   Flags: Precursor;
GN   Name=FGFBP2; Synonyms=KSP37; ORFNames=UNQ425/PRO1065;
//
ID   FGFP3_HUMAN             Reviewed;         258 AA.
AC   Q8TAT2; B2RD68; Q8NBN0;
DE   RecName: Full=Fibroblast growth factor-binding protein 3;
DE            Short=FGF-BP3;
DE            Short=FGF-binding protein 3;
DE            Short=FGFBP-3;
DE   Flags: Precursor;
GN   Name=FGFBP3; Synonyms=C10orf13; ORFNames=PSEC0101;
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:MGI.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IDA:MGI.
//
ID   FGFR1_HUMAN             Reviewed;         822 AA.
AC   P11362; A8K6T9; A8K8V5; C1KBH8; P17049; Q02063; Q02065; Q14306;
AC   Q14307; Q53H63; Q59H40; Q5BJG2; Q8N685; Q9UD50; Q9UDF0; Q9UDF1;
AC   Q9UDF2;
DE   RecName: Full=Fibroblast growth factor receptor 1;
DE            Short=FGFR-1;
DE            EC=2.7.10.1;
DE   AltName: Full=Basic fibroblast growth factor receptor 1;
DE            Short=BFGFR;
DE            Short=bFGF-R-1;
DE   AltName: Full=Fms-like tyrosine kinase 2;
DE            Short=FLT-2;
DE   AltName: Full=N-sam;
DE   AltName: Full=Proto-oncogene c-Fgr;
DE   AltName: CD_antigen=CD331;
DE   Flags: Precursor;
GN   Name=FGFR1; Synonyms=BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR;
DR   GuidetoPHARMACOLOGY; 1808; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.
DR   GO; GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0060117; P:auditory receptor cell development; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043009; P:chordate embryonic development; TAS:UniProtKB.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; TAS:ProtInc.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; TAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0042473; P:outer ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0090080; P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IMP:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; TAS:UniProtKB.
DR   GO; GO:0010518; P:positive regulation of phospholipase activity; TAS:UniProtKB.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0060665; P:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; IEA:Ensembl.
DR   GO; GO:0045595; P:regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0048378; P:regulation of lateral mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0048705; P:skeletal system morphogenesis; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0021847; P:ventricular zone neuroblast division; IEA:Ensembl.
//
ID   FGFR2_HUMAN             Reviewed;         821 AA.
AC   P21802; B4DFC2; E7EVR6; E9PCR0; P18443; Q01742; Q12922; Q14300;
AC   Q14301; Q14302; Q14303; Q14304; Q14305; Q14672; Q14718; Q14719;
AC   Q1KHY5; Q86YI4; Q8IXC7; Q96KL9; Q96KM0; Q96KM1; Q96KM2; Q9NZU2;
AC   Q9NZU3; Q9UD01; Q9UD02; Q9UIH3; Q9UIH4; Q9UIH5; Q9UIH6; Q9UIH7;
AC   Q9UIH8; Q9UM87; Q9UMC6; Q9UNS7; Q9UQH7; Q9UQH8; Q9UQH9; Q9UQI0;
DE   RecName: Full=Fibroblast growth factor receptor 2;
DE            Short=FGFR-2;
DE            EC=2.7.10.1;
DE   AltName: Full=K-sam;
DE            Short=KGFR;
DE   AltName: Full=Keratinocyte growth factor receptor;
DE   AltName: CD_antigen=CD332;
DE   Flags: Precursor;
GN   Name=FGFR2; Synonyms=BEK, KGFR, KSAM;
DR   GuidetoPHARMACOLOGY; 1809; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.
DR   GO; GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0060348; P:bone development; ISS:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; ISS:UniProtKB.
DR   GO; GO:0060349; P:bone morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060442; P:branching involved in prostate gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.
DR   GO; GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:UniProtKB.
DR   GO; GO:0060365; P:coronal suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; ISS:UniProtKB.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048568; P:embryonic organ development; ISS:UniProtKB.
DR   GO; GO:0048562; P:embryonic organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0061031; P:endodermal digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048730; P:epidermis morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; ISS:UniProtKB.
DR   GO; GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; ISS:UniProtKB.
DR   GO; GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; ISS:UniProtKB.
DR   GO; GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; ISS:UniProtKB.
DR   GO; GO:0022612; P:gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032808; P:lacrimal gland development; ISS:UniProtKB.
DR   GO; GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.
DR   GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR   GO; GO:0060174; P:limb bud formation; ISS:UniProtKB.
DR   GO; GO:0048286; P:lung alveolus development; ISS:UniProtKB.
DR   GO; GO:0030324; P:lung development; ISS:UniProtKB.
DR   GO; GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0060615; P:mammary gland bud formation; ISS:UniProtKB.
DR   GO; GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; ISS:UniProtKB.
DR   GO; GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.
DR   GO; GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.
DR   GO; GO:0048333; P:mesodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; ISS:UniProtKB.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; ISS:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; ISS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045839; P:negative regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042476; P:odontogenesis; ISS:UniProtKB.
DR   GO; GO:0021769; P:orbitofrontal cortex development; ISS:UniProtKB.
DR   GO; GO:0035265; P:organ growth; ISS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030916; P:otic vesicle formation; ISS:UniProtKB.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; ISS:UniProtKB.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.
DR   GO; GO:0060512; P:prostate gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0021860; P:pyramidal neuron development; ISS:UniProtKB.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060688; P:regulation of morphogenesis of a branching structure; ISS:UniProtKB.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; TAS:UniProtKB.
DR   GO; GO:0033688; P:regulation of osteoblast proliferation; TAS:UniProtKB.
DR   GO; GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048608; P:reproductive structure development; ISS:UniProtKB.
DR   GO; GO:0048705; P:skeletal system morphogenesis; TAS:UniProtKB.
DR   GO; GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.
DR   GO; GO:0048489; P:synaptic vesicle transport; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021847; P:ventricular zone neuroblast division; ISS:UniProtKB.
//
ID   FGFR3_HUMAN             Reviewed;         806 AA.
AC   P22607; D3DVP9; D3DVQ0; Q14308; Q16294; Q16608; Q59FL9;
DE   RecName: Full=Fibroblast growth factor receptor 3;
DE            Short=FGFR-3;
DE            EC=2.7.10.1;
DE   AltName: CD_antigen=CD333;
DE   Flags: Precursor;
GN   Name=FGFR3; Synonyms=JTK4;
DR   GuidetoPHARMACOLOGY; 1810; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.
DR   GO; GO:0005007; F:fibroblast growth factor-activated receptor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0061144; P:alveolar secondary septum development; IEA:Ensembl.
DR   GO; GO:0060385; P:axonogenesis involved in innervation; IEA:Ensembl.
DR   GO; GO:0070977; P:bone maturation; ISS:BHF-UCL.
DR   GO; GO:0060349; P:bone morphogenesis; TAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0035988; P:chondrocyte proliferation; TAS:UniProtKB.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0003416; P:endochondral bone growth; TAS:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; TAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0072148; P:epithelial cell fate commitment; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:1902178; P:fibroblast growth factor receptor apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060113; P:inner ear receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; TAS:ProtInc.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048640; P:negative regulation of developmental growth; ISS:BHF-UCL.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045839; P:negative regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0090080; P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:UniProtKB.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEA:Ensembl.
//
ID   FGFR4_HUMAN             Reviewed;         802 AA.
AC   P22455; G3JVM2; G3JVM5; G3JVM7; G3JVM9; O43785; Q14309; Q71TW8;
AC   Q8TDA0; Q96KE5;
DE   RecName: Full=Fibroblast growth factor receptor 4;
DE            Short=FGFR-4;
DE            EC=2.7.10.1;
DE   AltName: CD_antigen=CD334;
DE   Flags: Precursor;
GN   Name=FGFR4; Synonyms=JTK2, TKF;
DR   GuidetoPHARMACOLOGY; 1811; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.
DR   GO; GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0061144; P:alveolar secondary septum development; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0055062; P:phosphate ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0048554; P:positive regulation of metalloenzyme activity; IMP:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0070857; P:regulation of bile acid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:2000188; P:regulation of cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0010715; P:regulation of extracellular matrix disassembly; IMP:UniProtKB.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.
//
ID   FGGY_HUMAN              Reviewed;         551 AA.
AC   Q96C11; B1AK92; B1AK93; B1AK94; B2RDR8; D3DQ56; Q9HA63; Q9NV20;
DE   RecName: Full=FGGY carbohydrate kinase domain-containing protein;
DE            EC=2.7.1.-;
GN   Name=FGGY;
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0070050; P:neuron cellular homeostasis; IMP:UniProtKB.
//
ID   FGL1_HUMAN              Reviewed;         312 AA.
AC   Q08830; A6NKU4; Q4PJH9; Q53YF1; Q96KW6; Q96QM6;
DE   RecName: Full=Fibrinogen-like protein 1;
DE   AltName: Full=HP-041;
DE   AltName: Full=Hepassocin;
DE   AltName: Full=Hepatocyte-derived fibrinogen-related protein 1;
DE            Short=HFREP-1;
DE   AltName: Full=Liver fibrinogen-related protein 1;
DE            Short=LFIRE-1;
DE   Flags: Precursor;
GN   Name=FGL1; Synonyms=HFREP1;
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
//
ID   FGL2_HUMAN              Reviewed;         439 AA.
AC   Q14314;
DE   RecName: Full=Fibroleukin;
DE   AltName: Full=Fibrinogen-like protein 2;
DE   AltName: Full=pT49;
DE   Flags: Precursor;
GN   Name=FGL2;
//
ID   FGOP2_HUMAN             Reviewed;         253 AA.
AC   Q9NVK5; Q6R955; Q8N5L7; Q9P034; Q9UFK8;
DE   RecName: Full=FGFR1 oncogene partner 2;
GN   Name=FGFR1OP2; ORFNames=HSPC123;
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   FGRL1_HUMAN             Reviewed;         504 AA.
AC   Q8N441; B2RAU9; Q6PJN1; Q9BXN7; Q9H4D7;
DE   RecName: Full=Fibroblast growth factor receptor-like 1;
DE            Short=FGF receptor-like protein 1;
DE   AltName: Full=FGF homologous factor receptor;
DE   AltName: Full=FGFR-like protein;
DE   AltName: Full=Fibroblast growth factor receptor 5;
DE            Short=FGFR-5;
DE   Flags: Precursor;
GN   Name=FGFRL1; Synonyms=FGFR5, FHFR; ORFNames=UNQ480/PRO943;
DR   GO; GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0060539; P:diaphragm development; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:GOC.
DR   GO; GO:0003179; P:heart valve morphogenesis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
//
ID   FGR_HUMAN               Reviewed;         529 AA.
AC   P09769; D3DPL7; Q9UIQ3;
DE   RecName: Full=Tyrosine-protein kinase Fgr;
DE            EC=2.7.10.2;
DE   AltName: Full=Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog;
DE   AltName: Full=Proto-oncogene c-Fgr;
DE   AltName: Full=p55-Fgr;
DE   AltName: Full=p58-Fgr;
DE   AltName: Full=p58c-Fgr;
GN   Name=FGR; Synonyms=SRC2;
DR   GuidetoPHARMACOLOGY; 2024; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; ISS:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
//
ID   FHAD1_HUMAN             Reviewed;        1412 AA.
AC   B1AJZ9; Q0P6F5; Q8N8D3; Q8N9T6; Q8NA05;
DE   RecName: Full=Forkhead-associated domain-containing protein 1;
DE            Short=FHA domain-containing protein 1;
GN   Name=FHAD1; Synonyms=KIAA1937;
//
ID   FHDC1_HUMAN             Reviewed;        1143 AA.
AC   Q9C0D6;
DE   RecName: Full=FH2 domain-containing protein 1;
GN   Name=FHDC1; Synonyms=KIAA1727;
//
ID   FHIT_HUMAN              Reviewed;         147 AA.
AC   P49789; A2IAS9; A2IAT0; A2IAT6; A8K1A9; Q45QG9; Q6IU12;
DE   RecName: Full=Bis(5'-adenosyl)-triphosphatase;
DE            EC=3.6.1.29;
DE   AltName: Full=AP3A hydrolase;
DE            Short=AP3Aase;
DE   AltName: Full=Diadenosine 5',5'''-P1,P3-triphosphate hydrolase;
DE   AltName: Full=Dinucleosidetriphosphatase;
DE   AltName: Full=Fragile histidine triad protein;
GN   Name=FHIT;
DR   GO; GO:0047710; F:bis(5'-adenosyl)-triphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0016787; F:hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0009117; P:nucleotide metabolic process; TAS:ProtInc.
DR   GO; GO:0006163; P:purine nucleotide metabolic process; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FHL17_HUMAN             Reviewed;         183 AA.
AC   Q9BXU8; Q6NT24; Q6NTE2;
DE   RecName: Full=Ferritin heavy polypeptide-like 17;
DE   AltName: Full=Cancer/testis antigen 38;
DE            Short=CT38;
GN   Name=FTHL17;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
//
ID   FHL19_HUMAN             Reviewed;         201 AA.
AC   P0C7X4;
DE   RecName: Full=Putative ferritin heavy polypeptide-like 19;
DE   AltName: Full=Ferritin heavy polypeptide 1 pseudogene 19;
GN   Name=FTH1P19; Synonyms=FTHL19;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
//
ID   FHL1_HUMAN              Reviewed;         323 AA.
AC   Q13642; B7Z5T4; B7Z793; O95212; Q13230; Q13645; Q5JXI7; Q5M7Y6;
AC   Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630;
DE   RecName: Full=Four and a half LIM domains protein 1;
DE            Short=FHL-1;
DE   AltName: Full=Skeletal muscle LIM-protein 1;
DE            Short=SLIM;
DE            Short=SLIM-1;
GN   Name=FHL1; Synonyms=SLIM1;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IDA:BHF-UCL.
DR   GO; GO:0003254; P:regulation of membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
//
ID   FHL3_HUMAN              Reviewed;         280 AA.
AC   Q13643; D3DPT6; Q6I9T0; Q9BVA2;
DE   RecName: Full=Four and a half LIM domains protein 3;
DE            Short=FHL-3;
DE   AltName: Full=Skeletal muscle LIM-protein 2;
DE            Short=SLIM-2;
GN   Name=FHL3; Synonyms=SLIM2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   FHL2_HUMAN              Reviewed;         279 AA.
AC   Q14192; Q13229; Q13644; Q2I5I4; Q9P294;
DE   RecName: Full=Four and a half LIM domains protein 2;
DE            Short=FHL-2;
DE   AltName: Full=LIM domain protein DRAL;
DE   AltName: Full=Skeletal muscle LIM-protein 3;
DE            Short=SLIM-3;
GN   Name=FHL2; Synonyms=DRAL, SLIM3;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0055014; P:atrial cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
//
ID   FHL5_HUMAN              Reviewed;         284 AA.
AC   Q5TD97; B2RBD1; E1P526; Q5TD98; Q8WW21; Q9NQU2;
DE   RecName: Full=Four and a half LIM domains protein 5;
DE            Short=FHL-5;
DE   AltName: Full=Activator of cAMP-responsive element modulator in testis;
DE            Short=Activator of CREM in testis;
GN   Name=FHL5; Synonyms=ACT;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   FHOD1_HUMAN             Reviewed;        1164 AA.
AC   Q9Y613; Q59F76; Q6Y1F2; Q76MS8; Q8N521;
DE   RecName: Full=FH1/FH2 domain-containing protein 1;
DE   AltName: Full=Formin homolog overexpressed in spleen 1;
DE            Short=FHOS;
DE   AltName: Full=Formin homology 2 domain-containing protein 1;
GN   Name=FHOD1; Synonyms=FHOS, FHOS1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   FHOD3_HUMAN             Reviewed;        1422 AA.
AC   Q2V2M9; A8MQT4; E5F5Q0; Q642I2; Q6ZRQ7; Q86TF9; Q8N3A5; Q9C0G8;
AC   Q9H604; Q9H6G7;
DE   RecName: Full=FH1/FH2 domain-containing protein 3;
DE   AltName: Full=Formactin-2;
DE   AltName: Full=Formin homolog overexpressed in spleen 2;
DE            Short=hFHOS2;
GN   Name=FHOD3; Synonyms=FHOS2, KIAA1695;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051639; P:actin filament network formation; IEA:Ensembl.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
//
ID   FHR3_HUMAN              Reviewed;         330 AA.
AC   Q02985; B4DPR0; Q9UJ16;
DE   RecName: Full=Complement factor H-related protein 3;
DE            Short=FHR-3;
DE   AltName: Full=DOWN16;
DE   AltName: Full=H factor-like protein 3;
DE   Flags: Precursor;
GN   Name=CFHR3; Synonyms=CFHL3, FHR3;
//
ID   FHR1_HUMAN              Reviewed;         330 AA.
AC   Q03591; A8K465; Q3B774; Q9UJ17;
DE   RecName: Full=Complement factor H-related protein 1;
DE            Short=FHR-1;
DE   AltName: Full=H factor-like protein 1;
DE            Short=H-factor-like 1;
DE   AltName: Full=H36;
DE   Flags: Precursor;
GN   Name=CFHR1; Synonyms=CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2;
DR   GO; GO:0006956; P:complement activation; TAS:ProtInc.
//
ID   FHR2_HUMAN              Reviewed;         270 AA.
AC   P36980; Q14310; Q5T9T1;
DE   RecName: Full=Complement factor H-related protein 2;
DE            Short=FHR-2;
DE   AltName: Full=DDESK59;
DE   AltName: Full=H factor-like 3;
DE   AltName: Full=H factor-like protein 2;
DE   Flags: Precursor;
GN   Name=CFHR2; Synonyms=CFHL2, FHR2, HFL3;
//
ID   FHR4_HUMAN              Reviewed;         578 AA.
AC   Q92496; A8K9N7; B1ALQ9; C9J7J7; Q5DVJ7; Q9UJY6;
DE   RecName: Full=Complement factor H-related protein 4;
DE            Short=FHR-4;
DE   Flags: Precursor;
GN   Name=CFHR4; Synonyms=CFHL4, FHR4;
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; TAS:GOC.
//
ID   FHR5_HUMAN              Reviewed;         569 AA.
AC   Q9BXR6; Q2NKK2;
DE   RecName: Full=Complement factor H-related protein 5;
DE            Short=FHR-5;
DE   Flags: Precursor;
GN   Name=CFHR5; Synonyms=CFHL5, FHR5;
DR   GO; GO:0006957; P:complement activation, alternative pathway; NAS:UniProtKB.
//
ID   FIBA_HUMAN              Reviewed;         866 AA.
AC   P02671; A8K3E4; D3DP14; D3DP15; Q4QQH7; Q9BX62; Q9UCH2;
DE   RecName: Full=Fibrinogen alpha chain;
DE   Contains:
DE     RecName: Full=Fibrinopeptide A;
DE   Contains:
DE     RecName: Full=Fibrinogen alpha chain;
DE   Flags: Precursor;
GN   Name=FGA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0072377; P:blood coagulation, common pathway; IMP:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:2000261; P:negative regulation of blood coagulation, common pathway; TAS:BHF-UCL.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IDA:BHF-UCL.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IDA:BHF-UCL.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0090277; P:positive regulation of peptide hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; NAS:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0051258; P:protein polymerization; IDA:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   FIBB_HUMAN              Reviewed;         491 AA.
AC   P02675; B2R7G3; Q3KPF2;
DE   RecName: Full=Fibrinogen beta chain;
DE   Contains:
DE     RecName: Full=Fibrinopeptide B;
DE   Contains:
DE     RecName: Full=Fibrinogen beta chain;
DE   Flags: Precursor;
GN   Name=FGB;
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0044320; P:cellular response to leptin stimulus; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IDA:BHF-UCL.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IDA:BHF-UCL.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0090277; P:positive regulation of peptide hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; NAS:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0051258; P:protein polymerization; IDA:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   FIBG_HUMAN              Reviewed;         453 AA.
AC   P02679; A8K057; P04469; P04470; Q53Y18; Q96A14; Q96KJ3; Q9UC62;
AC   Q9UC63; Q9UCF3;
DE   RecName: Full=Fibrinogen gamma chain;
DE   Flags: Precursor;
GN   Name=FGG; ORFNames=PRO2061;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0043623; P:cellular protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IDA:BHF-UCL.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IDA:BHF-UCL.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0090277; P:positive regulation of peptide hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; NAS:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IDA:BHF-UCL.
DR   GO; GO:0051258; P:protein polymerization; IMP:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   FIBIN_HUMAN             Reviewed;         211 AA.
AC   Q8TAL6;
DE   RecName: Full=Fin bud initiation factor homolog;
DE   Flags: Precursor;
GN   Name=FIBIN; ORFNames=PSEC0235;
//
ID   FIBP_HUMAN              Reviewed;         364 AA.
AC   O43427; A8K0J7; Q27Q85; Q6IBQ3; Q9HD65;
DE   RecName: Full=Acidic fibroblast growth factor intracellular-binding protein;
DE            Short=aFGF intracellular-binding protein;
DE   AltName: Full=FGF-1 intracellular-binding protein;
GN   Name=FIBP;
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:MGI.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:ProtInc.
//
ID   FICD_HUMAN              Reviewed;         458 AA.
AC   Q9BVA6; O75406;
DE   RecName: Full=Adenosine monophosphate-protein transferase FICD;
DE            EC=2.7.7.n1;
DE   AltName: Full=AMPylator FICD;
DE   AltName: Full=FIC domain-containing protein;
DE   AltName: Full=Huntingtin yeast partner E;
DE   AltName: Full=Huntingtin-interacting protein 13;
DE            Short=HIP-13;
DE   AltName: Full=Huntingtin-interacting protein E;
GN   Name=FICD; Synonyms=HIP13, HYPE; ORFNames=UNQ3041/PRO9857;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0070733; F:protein adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0034259; P:negative regulation of Rho GTPase activity; TAS:UniProtKB.
DR   GO; GO:0018117; P:protein adenylylation; IDA:UniProtKB.
//
ID   FIG4_HUMAN              Reviewed;         907 AA.
AC   Q92562; Q53H49; Q5TCS6;
DE   RecName: Full=Polyphosphoinositide phosphatase;
DE            EC=3.1.3.-;
DE   AltName: Full=Phosphatidylinositol 3,5-bisphosphate 5-phosphatase;
DE   AltName: Full=SAC domain-containing protein 3;
GN   Name=FIG4; Synonyms=KIAA0274, SAC3;
DR   GO; GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; TAS:Reactome.
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IEA:Ensembl.
DR   GO; GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0032288; P:myelin assembly; IEA:Ensembl.
DR   GO; GO:0031642; P:negative regulation of myelination; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; TAS:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007033; P:vacuole organization; IEA:Ensembl.
//
ID   FIGL1_HUMAN             Reviewed;         674 AA.
AC   Q6PIW4; D3DVM6; Q86V18; Q8ND59; Q9H8P1; Q9H917;
DE   RecName: Full=Fidgetin-like protein 1;
DE            EC=3.6.4.-;
GN   Name=FIGNL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046034; P:ATP metabolic process; ISS:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0033687; P:osteoblast proliferation; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.
//
ID   FIGL2_HUMAN             Reviewed;         653 AA.
AC   A6NMB9;
DE   RecName: Full=Putative fidgetin-like protein 2;
GN   Name=FIGNL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
//
ID   FIGLA_HUMAN             Reviewed;         219 AA.
AC   Q6QHK4;
DE   RecName: Full=Factor in the germline alpha;
DE            Short=FIGalpha;
DE   AltName: Full=Class C basic helix-loop-helix protein 8;
DE            Short=bHLHc8;
DE   AltName: Full=Folliculogenesis-specific basic helix-loop-helix protein;
DE   AltName: Full=Transcription factor FIGa;
GN   Name=FIGLA; Synonyms=BHLHC8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048599; P:oocyte development; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FIGN_HUMAN              Reviewed;         759 AA.
AC   Q5HY92; B3KWM0; Q9H6M5; Q9NVZ9;
DE   RecName: Full=Fidgetin;
GN   Name=FIGN;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   FIL1L_HUMAN             Reviewed;        1135 AA.
AC   Q4L180; B2CNV7; B2CNV8; Q13597; Q2YDY5; Q6KFX5; Q6KFX6; Q6KFX7;
AC   Q8IUM3; Q8N6Z0;
DE   RecName: Full=Filamin A-interacting protein 1-like;
DE   AltName: Full=130 kDa GPBP-interacting protein;
DE   AltName: Full=90 kDa GPBP-interacting protein;
DE   AltName: Full=Protein down-regulated in ovarian cancer 1;
DE            Short=DOC-1;
GN   Name=FILIP1L; Synonyms=COL4A3BPIP, DOC1, GIP90;
//
ID   FILA_HUMAN              Reviewed;        4061 AA.
AC   P20930; Q01720; Q5T583; Q9UC71;
DE   RecName: Full=Filaggrin;
GN   Name=FLG;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0061436; P:establishment of skin barrier; IEP:UniProt.
DR   GO; GO:0030216; P:keratinocyte differentiation; TAS:BHF-UCL.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
//
ID   FILA2_HUMAN             Reviewed;        2391 AA.
AC   Q5D862; Q9H4U1;
DE   RecName: Full=Filaggrin-2;
DE            Short=FLG-2;
DE   AltName: Full=Intermediate filament-associated and psoriasis-susceptibility protein;
DE            Short=Ifapsoriasin;
GN   Name=FLG2; Synonyms=IFPS;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0061436; P:establishment of skin barrier; IEP:UniProt.
//
ID   FINC_HUMAN              Reviewed;        2386 AA.
AC   P02751; B7ZLF0; E9PE77; E9PG29; O95609; O95610; Q14312; Q14325;
AC   Q14326; Q17RV7; Q564H7; Q585T2; Q59EH1; Q60FE4; Q68DP8; Q68DP9;
AC   Q68DT4; Q6LDP6; Q6MZS0; Q6MZU5; Q6N025; Q6N0A6; Q86T27; Q8IVI8;
AC   Q96KP7; Q96KP8; Q96KP9; Q9H1B8; Q9HAP3; Q9UMK2;
DE   RecName: Full=Fibronectin;
DE            Short=FN;
DE   AltName: Full=Cold-insoluble globulin;
DE            Short=CIG;
DE   Contains:
DE     RecName: Full=Anastellin;
DE   Contains:
DE     RecName: Full=Ugl-Y1;
DE   Contains:
DE     RecName: Full=Ugl-Y2;
DE   Contains:
DE     RecName: Full=Ugl-Y3;
DE   Flags: Precursor;
GN   Name=FN1; Synonyms=FN;
DR   GO; GO:0005518; F:collagen binding; NAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; NAS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IDA:UniProt.
DR   GO; GO:0016504; F:peptidase activator activity; IEA:Ensembl.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007161; P:calcium-independent cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007044; P:cell-substrate junction assembly; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0009611; P:response to wounding; NAS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
//
ID   FIP1_HUMAN              Reviewed;         594 AA.
AC   Q6UN15; B4DIR3; G3XAD6; Q0VGE0; Q499Y4; Q49AU3; Q7Z608; Q8WVN3;
AC   Q96F80; Q9H077;
DE   RecName: Full=Pre-mRNA 3'-end-processing factor FIP1;
DE            Short=hFip1;
DE   AltName: Full=FIP1-like 1 protein;
DE   AltName: Full=Factor interacting with PAP;
DE   AltName: Full=Rearranged in hypereosinophilia;
GN   Name=FIP1L1; Synonyms=FIP1, RHE;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   FIS1_HUMAN              Reviewed;         152 AA.
AC   Q9Y3D6; Q9BTP3;
DE   RecName: Full=Mitochondrial fission 1 protein;
DE   AltName: Full=FIS1 homolog;
DE            Short=hFis1;
DE   AltName: Full=Tetratricopeptide repeat protein 11;
DE            Short=TPR repeat protein 11;
GN   Name=FIS1; Synonyms=TTC11; ORFNames=CGI-135;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IMP:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008053; P:mitochondrial fusion; IMP:UniProtKB.
DR   GO; GO:0000422; P:mitochondrion degradation; IDA:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:UniProtKB.
DR   GO; GO:0032471; P:negative regulation of endoplasmic reticulum calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IMP:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IMP:UniProtKB.
DR   GO; GO:0010821; P:regulation of mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IMP:UniProtKB.
//
ID   FITM1_HUMAN             Reviewed;         292 AA.
AC   A5D6W6; Q8IUQ7;
DE   RecName: Full=Fat storage-inducing transmembrane protein 1;
DE   AltName: Full=Fat-inducing protein 1;
GN   Name=FITM1; Synonyms=FIT1;
DR   GO; GO:0034389; P:lipid particle organization; ISS:BHF-UCL.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; ISS:BHF-UCL.
//
ID   FITM2_HUMAN             Reviewed;         262 AA.
AC   Q8N6M3; A1L492; B9EGQ4; Q5TE59; Q9H3Y1;
DE   RecName: Full=Fat storage-inducing transmembrane protein 2;
DE   AltName: Full=Fat-inducing protein 2;
GN   Name=FITM2; Synonyms=C20orf142, FIT2;
DR   GO; GO:0035356; P:cellular triglyceride homeostasis; ISS:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0034389; P:lipid particle organization; ISS:UniProtKB.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; ISS:BHF-UCL.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0010866; P:regulation of triglyceride biosynthetic process; ISS:BHF-UCL.
//
ID   FIZ1_HUMAN              Reviewed;         496 AA.
AC   Q96SL8; A2RU72; Q6ZMJ7;
DE   RecName: Full=Flt3-interacting zinc finger protein 1;
DE   AltName: Full=Zinc finger protein 798;
GN   Name=FIZ1; Synonyms=ZNF798;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FJX1_HUMAN              Reviewed;         437 AA.
AC   Q86VR8; B2RCA9; Q9UGK6;
DE   RecName: Full=Four-jointed box protein 1;
DE   AltName: Full=Four-jointed protein homolog;
DE   Flags: Precursor;
GN   Name=FJX1;
//
ID   FKB10_HUMAN             Reviewed;         582 AA.
AC   Q96AY3; Q7Z3R4; Q9H3N3; Q9H6N5; Q9UF89;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP10;
DE            Short=PPIase FKBP10;
DE            EC=5.2.1.8;
DE   AltName: Full=65 kDa FK506-binding protein;
DE            Short=65 kDa FKBP;
DE            Short=FKBP-65;
DE   AltName: Full=FK506-binding protein 10;
DE            Short=FKBP-10;
DE   AltName: Full=Immunophilin FKBP65;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   Name=FKBP10; Synonyms=FKBP65; ORFNames=PSEC0056;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKB11_HUMAN             Reviewed;         201 AA.
AC   Q9NYL4; B4DWB7;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP11;
DE            Short=PPIase FKBP11;
DE            EC=5.2.1.8;
DE   AltName: Full=19 kDa FK506-binding protein;
DE            Short=19 kDa FKBP;
DE            Short=FKBP-19;
DE   AltName: Full=FK506-binding protein 11;
DE            Short=FKBP-11;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   Name=FKBP11; Synonyms=FKBP19; ORFNames=UNQ336/PRO535;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKB14_HUMAN             Reviewed;         211 AA.
AC   Q9NWM8;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP14;
DE            Short=PPIase FKBP14;
DE            EC=5.2.1.8;
DE   AltName: Full=22 kDa FK506-binding protein;
DE            Short=22 kDa FKBP;
DE            Short=FKBP-22;
DE   AltName: Full=FK506-binding protein 14;
DE            Short=FKBP-14;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   Name=FKBP14; Synonyms=FKBP22; ORFNames=UNQ322/PRO381;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKB15_HUMAN             Reviewed;        1219 AA.
AC   Q5T1M5; Q05DK8; Q5T1M2; Q6DD85; Q9Y4D0;
DE   RecName: Full=FK506-binding protein 15;
DE            Short=FKBP-15;
DE   AltName: Full=133 kDa FK506-binding protein;
DE            Short=133 kDa FKBP;
DE            Short=FKBP-133;
DE   AltName: Full=WASP and FKBP-like;
DE            Short=WAFL;
GN   Name=FKBP15; Synonyms=KIAA0674;
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   FKB1A_HUMAN             Reviewed;         108 AA.
AC   P62942; D3DVW6; P20071; Q4VC47; Q6FGD9; Q6LEU3; Q9H103; Q9H566;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1A;
DE            Short=PPIase FKBP1A;
DE            EC=5.2.1.8;
DE   AltName: Full=12 kDa FK506-binding protein;
DE            Short=12 kDa FKBP;
DE            Short=FKBP-12;
DE   AltName: Full=Calstabin-1;
DE   AltName: Full=FK506-binding protein 1A;
DE            Short=FKBP-1A;
DE   AltName: Full=Immunophilin FKBP12;
DE   AltName: Full=Rotamase;
GN   Name=FKBP1A; Synonyms=FKBP1, FKBP12;
DR   GuidetoPHARMACOLOGY; 2609; -.
DR   GO; GO:0048185; F:activin binding; IPI:BHF-UCL.
DR   GO; GO:0005528; F:FK506 binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0005527; F:macrolide binding; NAS:BHF-UCL.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; ISS:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; ISS:BHF-UCL.
DR   GO; GO:0006458; P:'de novo' protein folding; TAS:BHF-UCL.
DR   GO; GO:0034205; P:beta-amyloid formation; IDA:BHF-UCL.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0043206; P:extracellular fibril organization; IDA:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060347; P:heart trabecula formation; ISS:BHF-UCL.
DR   GO; GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IDA:BHF-UCL.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0022417; P:protein maturation by protein folding; TAS:BHF-UCL.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:GOC.
DR   GO; GO:0042026; P:protein refolding; TAS:BHF-UCL.
DR   GO; GO:0032925; P:regulation of activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; IMP:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0042110; P:T cell activation; NAS:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
//
ID   FKB1B_HUMAN             Reviewed;         108 AA.
AC   P68106; Q13664; Q16645; Q53TM2; Q9BQ40;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B;
DE            Short=PPIase FKBP1B;
DE            EC=5.2.1.8;
DE   AltName: Full=12.6 kDa FK506-binding protein;
DE            Short=12.6 kDa FKBP;
DE            Short=FKBP-12.6;
DE   AltName: Full=FK506-binding protein 1B;
DE            Short=FKBP-1B;
DE   AltName: Full=Immunophilin FKBP12.6;
DE   AltName: Full=Rotamase;
DE   AltName: Full=h-FKBP-12;
GN   Name=FKBP1B; Synonyms=FKBP12.6, FKBP1L, FKBP9, OTK4;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0030551; F:cyclic nucleotide binding; IEA:Ensembl.
DR   GO; GO:0005528; F:FK506 binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0006458; P:'de novo' protein folding; TAS:BHF-UCL.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; TAS:BHF-UCL.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; TAS:BHF-UCL.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0010459; P:negative regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0032513; P:negative regulation of protein phosphatase type 2B activity; IDA:BHF-UCL.
DR   GO; GO:0051280; P:negative regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0019227; P:neuronal action potential propagation; IEA:Ensembl.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0048680; P:positive regulation of axon regeneration; IEA:Ensembl.
DR   GO; GO:0051284; P:positive regulation of sequestering of calcium ion; IDA:BHF-UCL.
DR   GO; GO:0022417; P:protein maturation by protein folding; TAS:BHF-UCL.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:BHF-UCL.
DR   GO; GO:0042026; P:protein refolding; TAS:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; ISS:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0051775; P:response to redox state; IDA:BHF-UCL.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0006939; P:smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
//
ID   FKB9L_HUMAN             Reviewed;         142 AA.
AC   Q75LS8; B2R7H1;
DE   RecName: Full=Putative FK506-binding protein 9-like protein;
GN   Name=FKBP9L;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   FKBP2_HUMAN             Reviewed;         142 AA.
AC   P26885; Q5BJH9; Q9BTS7;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP2;
DE            Short=PPIase FKBP2;
DE            EC=5.2.1.8;
DE   AltName: Full=13 kDa FK506-binding protein;
DE            Short=13 kDa FKBP;
DE            Short=FKBP-13;
DE   AltName: Full=FK506-binding protein 2;
DE            Short=FKBP-2;
DE   AltName: Full=Immunophilin FKBP13;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   Name=FKBP2; Synonyms=FKBP13;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKBP3_HUMAN             Reviewed;         224 AA.
AC   Q00688; B2R4Q9; Q14317;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP3;
DE            Short=PPIase FKBP3;
DE            EC=5.2.1.8;
DE   AltName: Full=25 kDa FK506-binding protein;
DE            Short=25 kDa FKBP;
DE            Short=FKBP-25;
DE   AltName: Full=FK506-binding protein 3;
DE            Short=FKBP-3;
DE   AltName: Full=Immunophilin FKBP25;
DE   AltName: Full=Rapamycin-selective 25 kDa immunophilin;
DE   AltName: Full=Rotamase;
GN   Name=FKBP3; Synonyms=FKBP25;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKBP4_HUMAN             Reviewed;         459 AA.
AC   Q02790; D3DUQ1; Q9UCP1; Q9UCV7;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP4;
DE            Short=PPIase FKBP4;
DE            EC=5.2.1.8;
DE   AltName: Full=51 kDa FK506-binding protein;
DE            Short=FKBP51;
DE   AltName: Full=52 kDa FK506-binding protein;
DE            Short=52 kDa FKBP;
DE            Short=FKBP-52;
DE   AltName: Full=59 kDa immunophilin;
DE            Short=p59;
DE   AltName: Full=FK506-binding protein 4;
DE            Short=FKBP-4;
DE   AltName: Full=FKBP59;
DE   AltName: Full=HSP-binding immunophilin;
DE            Short=HBI;
DE   AltName: Full=Immunophilin FKBP52;
DE   AltName: Full=Rotamase;
DE   Contains:
DE     RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed;
GN   Name=FKBP4; Synonyms=FKBP52;
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0005528; F:FK506 binding; TAS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:Ensembl.
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProtKB.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; TAS:ProtInc.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB.
DR   GO; GO:0006825; P:copper ion transport; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0046661; P:male sex differentiation; IEA:Ensembl.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0031111; P:negative regulation of microtubule polymerization or depolymerization; ISS:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0030850; P:prostate gland development; IEA:Ensembl.
DR   GO; GO:0031503; P:protein complex localization; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:GOC.
DR   GO; GO:0006463; P:steroid hormone receptor complex assembly; IEA:Ensembl.
//
ID   FKBP5_HUMAN             Reviewed;         457 AA.
AC   Q13451; F5H7R1; Q59EB8; Q5TGM6;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP5;
DE            Short=PPIase FKBP5;
DE            EC=5.2.1.8;
DE   AltName: Full=51 kDa FK506-binding protein;
DE            Short=51 kDa FKBP;
DE            Short=FKBP-51;
DE   AltName: Full=54 kDa progesterone receptor-associated immunophilin;
DE   AltName: Full=Androgen-regulated protein 6;
DE   AltName: Full=FF1 antigen;
DE   AltName: Full=FK506-binding protein 5;
DE            Short=FKBP-5;
DE   AltName: Full=FKBP54;
DE            Short=p54;
DE   AltName: Full=HSP90-binding immunophilin;
DE   AltName: Full=Rotamase;
GN   Name=FKBP5; Synonyms=AIG6, FKBP51;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProtKB.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:UniProtKB.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:GOC.
//
ID   FKBP7_HUMAN             Reviewed;         259 AA.
AC   Q9Y680; Q4ZG70; Q6V3B2; Q86U65; Q96DA4; Q9Y6B0;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP7;
DE            Short=PPIase FKBP7;
DE            EC=5.2.1.8;
DE   AltName: Full=23 kDa FK506-binding protein;
DE            Short=23 kDa FKBP;
DE            Short=FKBP-23;
DE   AltName: Full=FK506-binding protein 7;
DE            Short=FKBP-7;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   Name=FKBP7; Synonyms=FKBP23; ORFNames=UNQ670/PRO1304;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKBP8_HUMAN             Reviewed;         412 AA.
AC   Q14318; C8C9T5; Q53GU3; Q7Z349; Q86YK6;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP8;
DE            Short=PPIase FKBP8;
DE            EC=5.2.1.8;
DE   AltName: Full=38 kDa FK506-binding protein;
DE            Short=38 kDa FKBP;
DE            Short=FKBP-38;
DE            Short=hFKBP38;
DE   AltName: Full=FK506-binding protein 8;
DE            Short=FKBP-8;
DE   AltName: Full=FKBPR38;
DE   AltName: Full=Rotamase;
GN   Name=FKBP8; Synonyms=FKBP38;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FKBP6_HUMAN             Reviewed;         327 AA.
AC   O75344; B4DXT7; G3V0I2; Q7Z4T4; Q9UDS0;
DE   RecName: Full=Inactive peptidyl-prolyl cis-trans isomerase FKBP6;
DE            Short=Inactive PPIase FKBP6;
DE   AltName: Full=36 kDa FK506-binding protein;
DE            Short=36 kDa FKBP;
DE            Short=FKBP-36;
DE   AltName: Full=FK506-binding protein 6;
DE            Short=FKBP-6;
DE   AltName: Full=Immunophilin FKBP36;
GN   Name=FKBP6; Synonyms=FKBP36;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0051879; F:Hsp90 protein binding; ISS:UniProtKB.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   FKBP9_HUMAN             Reviewed;         570 AA.
AC   O95302; B3KY35; B7Z1G9; B7Z6H3; Q2M2A1; Q3MIR7; Q6IN76; Q6P2N1;
AC   Q96EX5; Q96IJ9;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP9;
DE            Short=PPIase FKBP9;
DE            EC=5.2.1.8;
DE   AltName: Full=63 kDa FK506-binding protein;
DE            Short=63 kDa FKBP;
DE            Short=FKBP-63;
DE   AltName: Full=FK506-binding protein 9;
DE            Short=FKBP-9;
DE   AltName: Full=Rotamase;
DE   Flags: Precursor;
GN   Name=FKBP9; Synonyms=FKBP60, FKBP63;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
//
ID   FKBPL_HUMAN             Reviewed;         349 AA.
AC   Q9UIM3; A8K5V3; B0UYX8; Q9H5G3;
DE   RecName: Full=FK506-binding protein-like;
DE   AltName: Full=WAF-1/CIP1 stabilizing protein 39;
DE            Short=WISp39;
GN   Name=FKBPL; Synonyms=DIR1, NG7;
DR   GO; GO:0005528; F:FK506 binding; IBA:RefGenome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0018208; P:peptidyl-proline modification; IBA:RefGenome.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
DR   GO; GO:0009314; P:response to radiation; NAS:UniProtKB.
//
ID   FKRP_HUMAN              Reviewed;         495 AA.
AC   Q9H9S5; A8K5G7;
DE   RecName: Full=Fukutin-related protein;
DE            EC=2.-.-.-;
GN   Name=FKRP;
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
//
ID   FKTN_HUMAN              Reviewed;         461 AA.
AC   O75072; B4DUX9; J3KP13; Q3MIJ1; Q96TE1; Q9P295;
DE   RecName: Full=Fukutin;
DE            EC=2.-.-.-;
DE   AltName: Full=Fukuyama-type congenital muscular dystrophy protein;
GN   Name=FKTN; Synonyms=FCMD;
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IMP:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0060049; P:regulation of protein glycosylation; NAS:BHF-UCL.
//
ID   FL2D_HUMAN              Reviewed;         396 AA.
AC   Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2;
DE   RecName: Full=Pre-mRNA-splicing regulator WTAP;
DE   AltName: Full=Female-lethal(2)D homolog;
DE            Short=hFL(2)D;
DE   AltName: Full=WT1-associated protein;
DE   AltName: Full=Wilms tumor 1-associating protein;
GN   Name=WTAP; Synonyms=KIAA0105;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0080009; P:mRNA methylation; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   FLCN_HUMAN              Reviewed;         579 AA.
AC   Q8NFG4; A6NJJ8; Q6ZRX1; Q96BD2; Q96BE4;
DE   RecName: Full=Folliculin;
DE   AltName: Full=BHD skin lesion fibrofolliculoma protein;
DE   AltName: Full=Birt-Hogg-Dube syndrome protein;
GN   Name=FLCN; Synonyms=BHD;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0007043; P:cell-cell junction assembly; ISS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:2001170; P:negative regulation of ATP biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:1901723; P:negative regulation of cell proliferation involved in kidney development; ISS:UniProtKB.
DR   GO; GO:2000506; P:negative regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0010823; P:negative regulation of mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:1900181; P:negative regulation of protein localization to nucleus; IDA:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0035065; P:regulation of histone acetylation; ISS:UniProtKB.
DR   GO; GO:2000973; P:regulation of pro-B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032006; P:regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0031929; P:TOR signaling; IMP:UniProtKB.
//
ID   FLI1_HUMAN              Reviewed;         452 AA.
AC   Q01543; B2R8H2; B4DFV4; B4DTC6; G3V183; Q14319; Q92480; Q9UE07;
DE   RecName: Full=Friend leukemia integration 1 transcription factor;
DE   AltName: Full=Proto-oncogene Fli-1;
DE   AltName: Full=Transcription factor ERGB;
GN   Name=FLI1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0007599; P:hemostasis; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FLII_HUMAN              Reviewed;        1269 AA.
AC   Q13045; B4DIL0; F5H407; J3QLG3;
DE   RecName: Full=Protein flightless-1 homolog;
GN   Name=FLII; Synonyms=FLIL;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FLIP1_HUMAN             Reviewed;        1213 AA.
AC   Q7Z7B0; B2RMU6; Q5VUL6; Q86TC3; Q8N8B9; Q96SK6; Q9NVI8; Q9ULE5;
DE   RecName: Full=Filamin-A-interacting protein 1;
DE            Short=FILIP;
GN   Name=FILIP1; Synonyms=KIAA1275;
//
ID   FLNA_HUMAN              Reviewed;        2647 AA.
AC   P21333; E9KL45; Q5HY53; Q5HY55; Q8NF52;
DE   RecName: Full=Filamin-A;
DE            Short=FLN-A;
DE   AltName: Full=Actin-binding protein 280;
DE            Short=ABP-280;
DE   AltName: Full=Alpha-filamin;
DE   AltName: Full=Endothelial actin-binding protein;
DE   AltName: Full=Filamin-1;
DE   AltName: Full=Non-muscle filamin;
GN   Name=FLNA; Synonyms=FLN, FLN1;
DR   GO; GO:0051015; F:actin filament binding; IDA:BHF-UCL.
DR   GO; GO:0034988; F:Fc-gamma receptor I complex binding; IDA:BHF-UCL.
DR   GO; GO:0001948; F:glycoprotein binding; IDA:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:BHF-UCL.
DR   GO; GO:0017160; F:Ral GTPase binding; IDA:BHF-UCL.
DR   GO; GO:0017048; F:Rho GTPase binding; IDA:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0051764; P:actin crosslink formation; IDA:BHF-UCL.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0007195; P:adenylate cyclase-inhibiting dopamine receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0051220; P:cytoplasmic sequestering of protein; IMP:BHF-UCL.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0045184; P:establishment of protein localization; IDA:BHF-UCL.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IMP:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IMP:BHF-UCL.
DR   GO; GO:0043113; P:receptor clustering; IDA:BHF-UCL.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IDA:MGI.
//
ID   FLNB_HUMAN              Reviewed;        2602 AA.
AC   O75369; B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; Q13706; Q59EC2;
AC   Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q9NRB5; Q9NT26;
AC   Q9UEV9;
DE   RecName: Full=Filamin-B;
DE            Short=FLN-B;
DE   AltName: Full=ABP-278;
DE   AltName: Full=ABP-280 homolog;
DE   AltName: Full=Actin-binding-like protein;
DE   AltName: Full=Beta-filamin;
DE   AltName: Full=Filamin homolog 1;
DE            Short=Fh1;
DE   AltName: Full=Filamin-3;
DE   AltName: Full=Thyroid autoantigen;
DE   AltName: Full=Truncated actin-binding protein;
DE            Short=Truncated ABP;
GN   Name=FLNB; Synonyms=FLN1L, FLN3, TABP, TAP;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
//
ID   FLNC_HUMAN              Reviewed;        2725 AA.
AC   Q14315; B2ZZ88; O95303; Q07985; Q9NS12; Q9NYE5; Q9UMR8; Q9Y503;
DE   RecName: Full=Filamin-C;
DE            Short=FLN-C;
DE            Short=FLNc;
DE   AltName: Full=ABP-280-like protein;
DE   AltName: Full=ABP-L;
DE   AltName: Full=Actin-binding-like protein;
DE   AltName: Full=Filamin-2;
DE   AltName: Full=Gamma-filamin;
GN   Name=FLNC; Synonyms=ABPL, FLN2;
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
//
ID   FLOT1_HUMAN             Reviewed;         427 AA.
AC   O75955; Q969J8; Q9UHW1; Q9UNV8;
DE   RecName: Full=Flotillin-1;
GN   Name=FLOT1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:Ensembl.
//
ID   FLOT2_HUMAN             Reviewed;         428 AA.
AC   Q14254;
DE   RecName: Full=Flotillin-2;
DE   AltName: Full=Epidermal surface antigen;
DE            Short=ESA;
DE   AltName: Full=Membrane component chromosome 17 surface marker 1;
GN   Name=FLOT2; Synonyms=ESA1, M17S1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   FLOWR_HUMAN             Reviewed;         172 AA.
AC   Q9UGQ2; B7Z3T8; B7Z5E1; F5GXX4; Q5SXD4; Q8NBM6;
DE   RecName: Full=Calcium channel flower homolog;
DE   AltName: Full=Calcium channel flower domain-containing protein 1;
GN   Name=CACFD1; Synonyms=C9orf7;
GN   ORFNames=PSEC0107, PSEC0248, UNQ3071/PRO9903;
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:InterPro.
//
ID   FLRT1_HUMAN             Reviewed;         646 AA.
AC   Q9NZU1; Q8WVA2;
DE   RecName: Full=Leucine-rich repeat transmembrane protein FLRT1;
DE   AltName: Full=Fibronectin-like domain-containing leucine-rich transmembrane protein 1;
DE   Flags: Precursor;
GN   Name=FLRT1; ORFNames=UNQ752/PRO1483;
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:GOC.
//
ID   FLRT2_HUMAN             Reviewed;         660 AA.
AC   O43155; A0AV84; B7ZLP3;
DE   RecName: Full=Leucine-rich repeat transmembrane protein FLRT2;
DE   AltName: Full=Fibronectin-like domain-containing leucine-rich transmembrane protein 2;
DE   Flags: Precursor;
GN   Name=FLRT2; Synonyms=KIAA0405; ORFNames=UNQ232/PRO265;
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:GOC.
//
ID   FLRT3_HUMAN             Reviewed;         649 AA.
AC   Q9NZU0; D3DW20; Q542Z9; Q96K39; Q96K42; Q96KB1; Q9P259;
DE   RecName: Full=Leucine-rich repeat transmembrane protein FLRT3;
DE   AltName: Full=Fibronectin-like domain-containing leucine-rich transmembrane protein 3;
DE   Flags: Precursor;
GN   Name=FLRT3; Synonyms=KIAA1469; ORFNames=UNQ856/PRO1865;
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:GOC.
//
ID   FLT3L_HUMAN             Reviewed;         235 AA.
AC   P49771; A0AVC2; B9EGH2; Q05C96;
DE   RecName: Full=Fms-related tyrosine kinase 3 ligand;
DE            Short=Flt3 ligand;
DE            Short=Flt3L;
DE   AltName: Full=SL cytokine;
DE   Flags: Precursor;
GN   Name=FLT3LG;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IDA:DFLAT.
DR   GO; GO:0030098; P:lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FLT3_HUMAN              Reviewed;         993 AA.
AC   P36888; A0AVG9; B7ZLT7; B7ZLT8; F5H0A0; Q13414;
DE   RecName: Full=Receptor-type tyrosine-protein kinase FLT3;
DE            EC=2.7.10.1;
DE   AltName: Full=FL cytokine receptor;
DE   AltName: Full=Fetal liver kinase-2;
DE            Short=FLK-2;
DE   AltName: Full=Fms-like tyrosine kinase 3;
DE            Short=FLT-3;
DE   AltName: Full=Stem cell tyrosine kinase 1;
DE            Short=STK-1;
DE   AltName: CD_antigen=CD135;
DE   Flags: Precursor;
GN   Name=FLT3; Synonyms=CD135, FLK2, STK1;
DR   GuidetoPHARMACOLOGY; 1807; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004896; F:cytokine receptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; ISS:UniProtKB.
DR   GO; GO:0035726; P:common myeloid progenitor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IDA:MGI.
DR   GO; GO:0001776; P:leukocyte homeostasis; ISS:UniProtKB.
DR   GO; GO:0046651; P:lymphocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0002318; P:myeloid progenitor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045578; P:negative regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; TAS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; TAS:UniProtKB.
DR   GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; TAS:UniProtKB.
DR   GO; GO:0002328; P:pro-B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0002572; P:pro-T cell differentiation; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
DR   GO; GO:0038084; P:vascular endothelial growth factor signaling pathway; TAS:GOC.
//
ID   FLVC1_HUMAN             Reviewed;         555 AA.
AC   Q9Y5Y0; Q1HE16; Q86XY9; Q9NVR9;
DE   RecName: Full=Feline leukemia virus subgroup C receptor-related protein 1;
DE            Short=Feline leukemia virus subgroup C receptor;
DE            Short=hFLVCR;
GN   Name=FLVCR1; Synonyms=FLVCR;
DR   GO; GO:0015232; F:heme transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IDA:MGI.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW.
DR   GO; GO:0060323; P:head morphogenesis; IEA:Ensembl.
DR   GO; GO:0097037; P:heme export; IMP:UniProtKB.
DR   GO; GO:0015886; P:heme transport; IMP:MGI.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006839; P:mitochondrial transport; IDA:MGI.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0046620; P:regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   FLVC2_HUMAN             Reviewed;         526 AA.
AC   Q9UPI3; B7Z485; Q53ZT9; Q96JY3; Q9NX90;
DE   RecName: Full=Feline leukemia virus subgroup C receptor-related protein 2;
DE   AltName: Full=Calcium-chelate transporter;
DE            Short=CCT;
GN   Name=FLVCR2; Synonyms=C14orf58;
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0015232; F:heme transporter activity; IDA:UniProtKB.
DR   GO; GO:0015886; P:heme transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   FM25A_HUMAN             Reviewed;          89 AA.
AC   B3EWG3; B2RV02; Q5VTM1;
DE   RecName: Full=Protein FAM25A;
GN   Name=FAM25A;
//
ID   FM25B_HUMAN             Reviewed;          89 AA.
AC   B3EWG4; B2RV02; Q5VTM1;
DE   RecName: Full=Protein FAM25B;
GN   Name=FAM25B;
//
ID   FM25C_HUMAN             Reviewed;          89 AA.
AC   B3EWG5; B2RV02; Q5VTM1;
DE   RecName: Full=Protein FAM25C;
GN   Name=FAM25C;
//
ID   FM25G_HUMAN             Reviewed;          89 AA.
AC   B3EWG6; B2RV02; Q5VTM1;
DE   RecName: Full=Protein FAM25G;
GN   Name=FAM25G;
//
ID   FMAS1_HUMAN             Reviewed;         363 AA.
AC   P0C7T7;
DE   RecName: Full=Putative uncharacterized protein FRMD6-AS1;
DE   AltName: Full=FRMD6 antisense RNA 1;
DE   AltName: Full=FRMD6 antisense gene protein 1;
GN   Name=FRMD6-AS1; Synonyms=C14orf82;
//
ID   FMN1_HUMAN              Reviewed;        1419 AA.
AC   Q68DA7; Q3B7I6; Q3ZAR4; Q6ZSY1;
DE   RecName: Full=Formin-1;
DE   AltName: Full=Limb deformity protein homolog;
GN   Name=FMN1; Synonyms=FMN, LD;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR   GO; GO:0035136; P:forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; IEA:Ensembl.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0051127; P:positive regulation of actin nucleation; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
//
ID   FMN2_HUMAN              Reviewed;        1722 AA.
AC   Q9NZ56; B0QZA7; Q59GF6; Q5VU37; Q9NZ55;
DE   RecName: Full=Formin-2;
GN   Name=FMN2;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:UniProtKB.
DR   GO; GO:0051295; P:establishment of meiotic spindle localization; ISS:BHF-UCL.
DR   GO; GO:0070649; P:formin-nucleated actin cable assembly; ISS:UniProtKB.
DR   GO; GO:0051758; P:homologous chromosome movement towards spindle pole involved in homologous chromosome segregation; ISS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046907; P:intracellular transport; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0048477; P:oogenesis; ISS:BHF-UCL.
DR   GO; GO:0040038; P:polar body extrusion after meiotic divisions; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   FMNL2_HUMAN             Reviewed;        1086 AA.
AC   Q96PY5; B2RZH5; Q14CC9; Q4ZG52; Q8N3E0;
DE   RecName: Full=Formin-like protein 2;
DE   AltName: Full=Formin homology 2 domain-containing protein 2;
GN   Name=FMNL2; Synonyms=FHOD2, KIAA1902;
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   FMNL3_HUMAN             Reviewed;        1028 AA.
AC   Q8IVF7; B0JZA7; Q6ZRJ1;
DE   RecName: Full=Formin-like protein 3;
DE   AltName: Full=Formin homology 2 domain-containing protein 3;
DE   AltName: Full=WW domain-binding protein 3;
DE            Short=WBP-3;
GN   Name=FMNL3; Synonyms=FHOD3, KIAA2014, WBP3;
DR   GO; GO:0032794; F:GTPase activating protein binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   FMNL_HUMAN              Reviewed;        1100 AA.
AC   O95466; D2DGW2; Q6DKG5; Q6IBP3; Q86UH1; Q8N671; Q8TDH1; Q96H10;
DE   RecName: Full=Formin-like protein 1;
DE   AltName: Full=CLL-associated antigen KW-13;
DE   AltName: Full=Leukocyte formin;
GN   Name=FMNL1; Synonyms=C17orf1, C17orf1B, FMNL;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0032794; F:GTPase activating protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048365; F:Rac GTPase binding; ISS:UniProtKB.
DR   GO; GO:0051014; P:actin filament severing; ISS:UniProtKB.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0006929; P:substrate-dependent cell migration; IEA:Ensembl.
//
ID   FMO1_HUMAN              Reviewed;         532 AA.
AC   Q01740; A8K248; B7Z3P4; Q5QPT2; Q9UJC2;
DE   RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 1;
DE            EC=1.14.13.8;
DE   AltName: Full=Dimethylaniline oxidase 1;
DE   AltName: Full=Fetal hepatic flavin-containing monooxygenase 1;
DE            Short=FMO 1;
GN   Name=FMO1;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IDA:MGI.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0070995; P:NADPH oxidation; IDA:BHF-UCL.
DR   GO; GO:0006082; P:organic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009404; P:toxin metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   FMO2_HUMAN              Reviewed;         471 AA.
AC   Q99518; Q5EBX4; Q86U73; Q9BRX1;
DE   RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 2;
DE            EC=1.14.13.8;
DE   AltName: Full=Dimethylaniline oxidase 2;
DE   AltName: Full=FMO 1B1;
DE   AltName: Full=Pulmonary flavin-containing monooxygenase 2;
DE            Short=FMO 2;
GN   Name=FMO2;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; TAS:Reactome.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006739; P:NADP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0070995; P:NADPH oxidation; IDA:UniProtKB.
DR   GO; GO:0006082; P:organic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0072592; P:oxygen metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009404; P:toxin metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:BHF-UCL.
//
ID   FMO3_HUMAN              Reviewed;         532 AA.
AC   P31513; B2R816; Q14854; Q8N5N5;
DE   RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 3;
DE            EC=1.14.13.8;
DE   AltName: Full=Dimethylaniline oxidase 3;
DE   AltName: Full=FMO II;
DE   AltName: Full=FMO form 2;
DE   AltName: Full=Hepatic flavin-containing monooxygenase 3;
DE            Short=FMO 3;
DE   AltName: Full=Trimethylamine monooxygenase;
DE            EC=1.14.13.148;
GN   Name=FMO3;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; TAS:Reactome.
DR   GO; GO:0050661; F:NADP binding; IEA:Ensembl.
DR   GO; GO:0034899; F:trimethylamine monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0017144; P:drug metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   FMO4_HUMAN              Reviewed;         558 AA.
AC   P31512; Q53XR0;
DE   RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 4;
DE            EC=1.14.13.8;
DE   AltName: Full=Dimethylaniline oxidase 4;
DE   AltName: Full=Hepatic flavin-containing monooxygenase 4;
DE            Short=FMO 4;
GN   Name=FMO4; Synonyms=FMO2;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; NAS:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
//
ID   FMO5_HUMAN              Reviewed;         533 AA.
AC   P49326; B2RBG1; C9JJD1; Q8IV22;
DE   RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5;
DE            EC=1.14.13.8;
DE   AltName: Full=Dimethylaniline oxidase 5;
DE   AltName: Full=Hepatic flavin-containing monooxygenase 5;
DE            Short=FMO 5;
GN   Name=FMO5;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
//
ID   FMO6_HUMAN              Reviewed;         539 AA.
AC   O60774;
DE   RecName: Full=Putative dimethylaniline monooxygenase [N-oxide-forming] 6;
DE            EC=1.14.13.8;
DE   AltName: Full=Dimethylaniline oxidase 6;
DE   AltName: Full=Flavin-containing monooxygenase 6;
DE            Short=FMO 6;
GN   Name=FMO6P; Synonyms=FMO6;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
//
ID   FMOD_HUMAN              Reviewed;         376 AA.
AC   Q06828; Q15331; Q8IV47;
DE   RecName: Full=Fibromodulin;
DE            Short=FM;
DE   AltName: Full=Collagen-binding 59 kDa protein;
DE   AltName: Full=Keratan sulfate proteoglycan fibromodulin;
DE            Short=KSPG fibromodulin;
DE   Flags: Precursor;
GN   Name=FMOD; Synonyms=FM, SLRR2E;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007181; P:transforming growth factor beta receptor complex assembly; TAS:ProtInc.
//
ID   FMR1N_HUMAN             Reviewed;         255 AA.
AC   Q8N0W7; D3DWT3;
DE   RecName: Full=Fragile X mental retardation 1 neighbor protein;
DE   AltName: Full=Cancer/testis antigen 37;
DE            Short=CT37;
DE   AltName: Full=Sarcoma antigen NY-SAR-35;
GN   Name=FMR1NB;
//
ID   FMR1_HUMAN              Reviewed;         632 AA.
AC   Q06787; A6NNH4; D3DWT0; D3DWT1; D3DWT2; Q16578; Q5PQZ6; Q99054;
DE   RecName: Full=Fragile X mental retardation protein 1;
DE            Short=FMRP;
DE            Short=Protein FMR-1;
GN   Name=FMR1;
DR   GO; GO:0003729; F:mRNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0045947; P:negative regulation of translational initiation; ISS:UniProtKB.
//
ID   FMT_HUMAN               Reviewed;         389 AA.
AC   Q96DP5;
DE   RecName: Full=Methionyl-tRNA formyltransferase, mitochondrial;
DE            Short=MtFMT;
DE            EC=2.1.2.9;
DE   Flags: Precursor;
GN   Name=MTFMT; Synonyms=FMT, FMT1;
DR   GO; GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:UniProtKB-EC.
//
ID   FN3K_HUMAN              Reviewed;         309 AA.
AC   Q9H479;
DE   RecName: Full=Fructosamine-3-kinase;
DE            EC=2.7.1.-;
GN   Name=FN3K;
DR   GO; GO:0030387; F:fructosamine-3-kinase activity; NAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0030393; P:fructoselysine metabolic process; NAS:UniProtKB.
//
ID   FNBP1_HUMAN             Reviewed;         617 AA.
AC   Q96RU3; O60301; Q3MIN8; Q5TC87; Q5TC88; Q6P658; Q7LGG2; Q9H8H8;
AC   Q9NWD1;
DE   RecName: Full=Formin-binding protein 1;
DE   AltName: Full=Formin-binding protein 17;
DE            Short=hFBP17;
GN   Name=FNBP1; Synonyms=FBP17, KIAA0554;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
//
ID   FNBP4_HUMAN             Reviewed;        1017 AA.
AC   Q8N3X1; Q9H985; Q9NT81; Q9Y2L7;
DE   RecName: Full=Formin-binding protein 4;
DE   AltName: Full=Formin-binding protein 30;
GN   Name=FNBP4; Synonyms=FBP30, KIAA1014;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FND3A_HUMAN             Reviewed;        1198 AA.
AC   Q9Y2H6; B4DYG1; Q5HYC9; Q5JVF8; Q5JVF9; Q6EVH3; Q6EVH4; Q6N020;
AC   Q6P9D5; Q6ZME4; Q9H1W1;
DE   RecName: Full=Fibronectin type-III domain-containing protein 3A;
DE   AltName: Full=Human gene expressed in odontoblasts;
GN   Name=FNDC3A; Synonyms=FNDC3, HUGO, KIAA0970;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   FND3B_HUMAN             Reviewed;        1204 AA.
AC   Q53EP0; B2RB36; B3KXR8; D3DNQ7; Q5U5T8; Q6PIJ3; Q6UXG1; Q6UXZ5;
AC   Q8IXB2; Q8NBU7; Q96D78; Q9H5I7; Q9NSQ8;
DE   RecName: Full=Fibronectin type III domain-containing protein 3B;
DE   AltName: Full=Factor for adipocyte differentiation 104;
DE   AltName: Full=HCV NS5A-binding protein 37;
GN   Name=FNDC3B; Synonyms=FAD104, NS5ABP37;
GN   ORFNames=UNQ2421/PRO4979/PRO34274;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
//
ID   FNDC1_HUMAN             Reviewed;        1894 AA.
AC   Q4ZHG4; A6H8X2; B7ZBR4; B7ZBR5; B9EK49; Q5JPI0; Q5VU31; Q5VU32;
AC   Q5VXX4; Q70CQ6; Q96JG1;
DE   RecName: Full=Fibronectin type III domain-containing protein 1;
DE   AltName: Full=Activation-associated cDNA protein;
DE   AltName: Full=Expressed in synovial lining protein;
DE   Flags: Precursor;
GN   Name=FNDC1; Synonyms=FNDC2, KIAA1866, MEL4B3;
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051223; P:regulation of protein transport; IEA:Ensembl.
//
ID   FNDC4_HUMAN             Reviewed;         234 AA.
AC   Q9H6D8; D6W560;
DE   RecName: Full=Fibronectin type III domain-containing protein 4;
DE   AltName: Full=Fibronectin type III repeat-containing protein 1;
DE   Flags: Precursor;
GN   Name=FNDC4; Synonyms=FRCP1; ORFNames=UNQ6389/PRO21134;
//
ID   FNDC5_HUMAN             Reviewed;         212 AA.
AC   Q8NAU1; A6NMC9; D3DPQ6; Q6P6D9; Q7Z676;
DE   RecName: Full=Fibronectin type III domain-containing protein 5;
DE   AltName: Full=Fibronectin type III repeat-containing protein 2;
DE   Contains:
DE     RecName: Full=Irisin;
DE   Flags: Precursor;
GN   Name=FNDC5; Synonyms=FRCP2;
DR   GO; GO:0090336; P:positive regulation of brown fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0014850; P:response to muscle activity; ISS:UniProtKB.
//
ID   FNDC7_HUMAN             Reviewed;         733 AA.
AC   Q5VTL7; A1L468; E9PAZ5; Q6PF16; Q8NA51;
DE   RecName: Full=Fibronectin type III domain-containing protein 7;
DE   Flags: Precursor;
GN   Name=FNDC7;
//
ID   FNDC9_HUMAN             Reviewed;         224 AA.
AC   Q8TBE3; A8K0Y6;
DE   RecName: Full=Fibronectin type III domain-containing protein 9;
GN   Name=FNDC9; Synonyms=C5orf40;
//
ID   FNDC8_HUMAN             Reviewed;         324 AA.
AC   Q8TC99; B2R9G6; Q9UFC2;
DE   RecName: Full=Fibronectin type III domain-containing protein 8;
GN   Name=FNDC8;
//
ID   FNIP1_HUMAN             Reviewed;        1166 AA.
AC   Q8TF40; D6RJH5; Q86T47; Q9BUT0;
DE   RecName: Full=Folliculin-interacting protein 1;
GN   Name=FNIP1; Synonyms=KIAA1961;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:UniProtKB.
DR   GO; GO:0002327; P:immature B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0002904; P:positive regulation of B cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:2000973; P:regulation of pro-B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031929; P:TOR signaling; IMP:UniProtKB.
//
ID   FNIP2_HUMAN             Reviewed;        1114 AA.
AC   Q9P278; Q05DC3; Q96I31; Q9H994;
DE   RecName: Full=Folliculin-interacting protein 2;
DE   AltName: Full=FNIP1-like protein;
DE   AltName: Full=O6-methylguanine-induced apoptosis 1 protein;
GN   Name=FNIP2; Synonyms=FNIPL, KIAA1450, MAPO1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IDA:UniProtKB.
//
ID   FNTA_HUMAN              Reviewed;         379 AA.
AC   P49354; A6NJW0; Q53XJ9; Q9UDC1;
DE   RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha;
DE            EC=2.5.1.58;
DE            EC=2.5.1.59;
DE   AltName: Full=CAAX farnesyltransferase subunit alpha;
DE   AltName: Full=FTase-alpha;
DE   AltName: Full=Ras proteins prenyltransferase subunit alpha;
DE   AltName: Full=Type I protein geranyl-geranyltransferase subunit alpha;
DE            Short=GGTase-I-alpha;
GN   Name=FNTA;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.
DR   GO; GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008017; F:microtubule binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004660; F:protein farnesyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004661; F:protein geranylgeranyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0090045; P:positive regulation of deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0090044; P:positive regulation of tubulin deacetylation; IDA:BHF-UCL.
DR   GO; GO:0018343; P:protein farnesylation; IDA:UniProtKB.
DR   GO; GO:0018344; P:protein geranylgeranylation; IDA:UniProtKB.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   FNTB_HUMAN              Reviewed;         437 AA.
AC   P49356; B2RDX6; B4E1A0;
DE   RecName: Full=Protein farnesyltransferase subunit beta;
DE            Short=FTase-beta;
DE            EC=2.5.1.58;
DE   AltName: Full=CAAX farnesyltransferase subunit beta;
DE   AltName: Full=Ras proteins prenyltransferase subunit beta;
GN   Name=FNTB;
DR   GO; GO:0004311; F:farnesyltranstransferase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004660; F:protein farnesyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IEA:Ensembl.
DR   GO; GO:0018343; P:protein farnesylation; IEA:InterPro.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:InterPro.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0010035; P:response to inorganic substance; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   FOCAD_HUMAN             Reviewed;        1801 AA.
AC   Q5VW36; D3DRJ9; Q6ZME1; Q8IZG0; Q96JM8; Q96MS9; Q9BVF3; Q9NX87;
DE   RecName: Full=Focadhesin;
GN   Name=FOCAD; Synonyms=KIAA1797;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   FOG1_HUMAN              Reviewed;        1006 AA.
AC   Q8IX07;
DE   RecName: Full=Zinc finger protein ZFPM1;
DE   AltName: Full=Friend of GATA protein 1;
DE            Short=FOG-1;
DE            Short=Friend of GATA 1;
DE   AltName: Full=Zinc finger protein 89A;
DE   AltName: Full=Zinc finger protein multitype 1;
GN   Name=ZFPM1; Synonyms=FOG1, ZFN89A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060318; P:definitive erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; ISS:BHF-UCL.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0030851; P:granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   GO; GO:0030219; P:megakaryocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0003192; P:mitral valve formation; ISS:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045403; P:negative regulation of interleukin-4 biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0060377; P:negative regulation of mast cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030220; P:platelet formation; IGI:BHF-UCL.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0060319; P:primitive erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032642; P:regulation of chemokine production; IEA:Ensembl.
DR   GO; GO:0010724; P:regulation of definitive erythrocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0002295; P:T-helper cell lineage commitment; IC:BHF-UCL.
DR   GO; GO:0071733; P:transcriptional activation by promoter-enhancer looping; ISS:BHF-UCL.
DR   GO; GO:0003195; P:tricuspid valve formation; ISS:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   FOG2_HUMAN              Reviewed;        1151 AA.
AC   Q8WW38; Q32MA6; Q9NPL7; Q9NPS4; Q9UNI5;
DE   RecName: Full=Zinc finger protein ZFPM2;
DE   AltName: Full=Friend of GATA protein 2;
DE            Short=FOG-2;
DE            Short=Friend of GATA 2;
DE            Short=hFOG-2;
DE   AltName: Full=Zinc finger protein 89B;
DE   AltName: Full=Zinc finger protein multitype 2;
GN   Name=ZFPM2; Synonyms=FOG2, ZNF89B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001071; F:nucleic acid binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; NAS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.
DR   GO; GO:2000195; P:negative regulation of female gonad development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:2000020; P:positive regulation of male gonad development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0003221; P:right ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL.
//
ID   FOH1B_HUMAN             Reviewed;         442 AA.
AC   Q9HBA9;
DE   RecName: Full=Putative N-acetylated-alpha-linked acidic dipeptidase;
DE            Short=NAALADase;
DE            EC=3.4.-.-;
DE   AltName: Full=Cell growth-inhibiting gene 26 protein;
DE   AltName: Full=Prostate-specific membrane antigen-like protein;
DE   AltName: Full=Putative folate hydrolase 1B;
GN   Name=FOLH1B; Synonyms=PSMAL; ORFNames=GIG26;
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
//
ID   FOLC_HUMAN              Reviewed;         587 AA.
AC   Q05932; B3KPW4; B7Z2Z3; F5H0K6; Q5JU19; Q5JU22; Q6P2P6;
DE   RecName: Full=Folylpolyglutamate synthase, mitochondrial;
DE            EC=6.3.2.17;
DE   AltName: Full=Folylpoly-gamma-glutamate synthetase;
DE            Short=FPGS;
DE   AltName: Full=Tetrahydrofolylpolyglutamate synthase;
DE            Short=Tetrahydrofolate synthase;
DE   Flags: Precursor;
GN   Name=FPGS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   FOLH1_HUMAN             Reviewed;         750 AA.
AC   Q04609; A4UU12; A9CB79; B7Z312; B7Z343; D3DQS5; E9PDX8; O43748;
AC   Q16305; Q541A4; Q8TAY3; Q9NP15; Q9NYE2; Q9P1P8;
DE   RecName: Full=Glutamate carboxypeptidase 2;
DE            EC=3.4.17.21;
DE   AltName: Full=Cell growth-inhibiting gene 27 protein;
DE   AltName: Full=Folate hydrolase 1;
DE   AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase;
DE            Short=FGCP;
DE   AltName: Full=Glutamate carboxypeptidase II;
DE            Short=GCPII;
DE   AltName: Full=Membrane glutamate carboxypeptidase;
DE            Short=mGCP;
DE   AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I;
DE            Short=NAALADase I;
DE   AltName: Full=Prostate-specific membrane antigen;
DE            Short=PSM;
DE            Short=PSMA;
DE   AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;
GN   Name=FOLH1; Synonyms=FOLH, NAALAD1, PSM, PSMA; ORFNames=GIG27;
DR   GuidetoPHARMACOLOGY; 1606; -.
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; NAS:UniProtKB.
DR   GO; GO:0006760; P:folic acid-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   FOLR1_HUMAN             Reviewed;         257 AA.
AC   P15328; Q53EW2; Q6FGT8; Q6LC90; Q9UCT2;
DE   RecName: Full=Folate receptor alpha;
DE            Short=FR-alpha;
DE   AltName: Full=Adult folate-binding protein;
DE            Short=FBP;
DE   AltName: Full=Folate receptor 1;
DE   AltName: Full=Folate receptor, adult;
DE   AltName: Full=KB cells FBP;
DE   AltName: Full=Ovarian tumor-associated antigen MOv18;
DE   Flags: Precursor;
GN   Name=FOLR1; Synonyms=FOLR;
DR   GO; GO:0005542; F:folic acid binding; IDA:UniProtKB.
DR   GO; GO:0008517; F:folic acid transporter activity; IMP:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0046655; P:folic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0015884; P:folic acid transport; IMP:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
//
ID   FOLR2_HUMAN             Reviewed;         255 AA.
AC   P14207;
DE   RecName: Full=Folate receptor beta;
DE            Short=FR-beta;
DE   AltName: Full=Folate receptor 2;
DE   AltName: Full=Folate receptor, fetal/placental;
DE   AltName: Full=Placental folate-binding protein;
DE            Short=FBP;
DE   Flags: Precursor;
GN   Name=FOLR2;
DR   GO; GO:0005542; F:folic acid binding; IDA:UniProtKB.
DR   GO; GO:0008517; F:folic acid transporter activity; IDA:UniProtKB.
DR   GO; GO:0015884; P:folic acid transport; IDA:UniProtKB.
//
ID   FOLR3_HUMAN             Reviewed;         243 AA.
AC   P41439;
DE   RecName: Full=Folate receptor gamma;
DE            Short=FR-gamma;
DE   AltName: Full=Folate receptor 3;
DE   Flags: Precursor;
GN   Name=FOLR3;
DR   GO; GO:0005542; F:folic acid binding; TAS:ProtInc.
DR   GO; GO:0015884; P:folic acid transport; TAS:ProtInc.
//
ID   FONG_HUMAN              Reviewed;         147 AA.
AC   E5RQL4;
DE   RecName: Full=Formiminotransferase N-terminal subdomain-containing protein;
DE   AltName: Full=Formiminotransferase-cyclodeaminase N-terminal-like protein;
DE   Flags: Precursor;
GN   Name=FTCDNL1; Synonyms=FONG;
DR   GO; GO:0005542; F:folic acid binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
//
ID   FOPNL_HUMAN             Reviewed;         174 AA.
AC   Q96NB1;
DE   RecName: Full=LisH domain-containing protein FOPNL;
DE   AltName: Full=FGFR1OP N-terminal-like protein;
DE   AltName: Full=FOP-related protein of 20 kDa;
GN   Name=FOPNL; Synonyms=C16orf63, FOR20, PHSECRG2;
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
//
ID   FOSB_HUMAN              Reviewed;         338 AA.
AC   P53539; A8K9K5; A8VJE1; E9PHJ3;
DE   RecName: Full=Protein fosB;
DE   AltName: Full=G0/G1 switch regulatory protein 3;
GN   Name=FOSB; Synonyms=G0S3;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   FOSL2_HUMAN             Reviewed;         326 AA.
AC   P15408; B2RD58; B3KP27; B4DYV4; Q6FG46;
DE   RecName: Full=Fos-related antigen 2;
DE            Short=FRA-2;
GN   Name=FOSL2; Synonyms=FRA2;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   FOSL1_HUMAN             Reviewed;         271 AA.
AC   P15407; Q6FG51;
DE   RecName: Full=Fos-related antigen 1;
DE            Short=FRA-1;
GN   Name=FOSL1; Synonyms=FRA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007296; P:vitellogenesis; IEA:Ensembl.
//
ID   FOS_HUMAN               Reviewed;         380 AA.
AC   P01100; P18849;
DE   RecName: Full=Proto-oncogene c-Fos;
DE   AltName: Full=Cellular oncogene fos;
DE   AltName: Full=G0/G1 switch regulatory protein 7;
GN   Name=FOS; Synonyms=G0S7;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IDA:BHF-UCL.
DR   GO; GO:0001661; P:conditioned taste aversion; IEA:Ensembl.
DR   GO; GO:0006306; P:DNA methylation; TAS:ProtInc.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   FOXA1_HUMAN             Reviewed;         472 AA.
AC   P55317; B2R9H6; Q9H2A0;
DE   RecName: Full=Hepatocyte nuclear factor 3-alpha;
DE            Short=HNF-3-alpha;
DE            Short=HNF-3A;
DE   AltName: Full=Forkhead box protein A1;
DE   AltName: Full=Transcription factor 3A;
DE            Short=TCF-3A;
GN   Name=FOXA1; Synonyms=HNF3A, TCF3A;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; ISS:UniProtKB.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0060743; P:epithelial cell maturation involved in prostate gland development; IBA:RefGenome.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IBA:RefGenome.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048665; P:neuron fate specification; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IC:BHF-UCL.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IBA:RefGenome.
DR   GO; GO:0060741; P:prostate gland stromal morphogenesis; IBA:RefGenome.
DR   GO; GO:0032355; P:response to estradiol; IDA:UniProtKB.
DR   GO; GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXA2_HUMAN             Reviewed;         457 AA.
AC   Q9Y261; Q8WUW4; Q96DF7;
DE   RecName: Full=Hepatocyte nuclear factor 3-beta;
DE            Short=HNF-3-beta;
DE            Short=HNF-3B;
DE   AltName: Full=Forkhead box protein A2;
DE   AltName: Full=Transcription factor 3B;
DE            Short=TCF-3B;
GN   Name=FOXA2; Synonyms=HNF3B, TCF3B;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0021533; P:cell differentiation in hindbrain; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0061448; P:connective tissue development; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0001705; P:ectoderm formation; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IDA:BHF-UCL.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IBA:RefGenome.
DR   GO; GO:0001701; P:in utero embryonic development; IBA:RefGenome.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:2000971; P:negative regulation of detection of glucose; ISS:BHF-UCL.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0033132; P:negative regulation of glucokinase activity; ISS:BHF-UCL.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; ISS:BHF-UCL.
DR   GO; GO:0048665; P:neuron fate specification; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IC:BHF-UCL.
DR   GO; GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.
DR   GO; GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; ISS:BHF-UCL.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0090009; P:primitive streak formation; ISS:UniProtKB.
DR   GO; GO:0030193; P:regulation of blood coagulation; IDA:UniProtKB.
DR   GO; GO:0010817; P:regulation of hormone levels; IBA:RefGenome.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:BHF-UCL.
DR   GO; GO:0019218; P:regulation of steroid metabolic process; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000976; P:regulation of transcription from RNA polymerase II promoter involved in detection of glucose; ISS:BHF-UCL.
DR   GO; GO:0070741; P:response to interleukin-6; TAS:UniProtKB.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXA3_HUMAN             Reviewed;         350 AA.
AC   P55318; A9LYI5; Q53F16; Q9UMW9;
DE   RecName: Full=Hepatocyte nuclear factor 3-gamma;
DE            Short=HNF-3-gamma;
DE            Short=HNF-3G;
DE   AltName: Full=Fork head-related protein FKH H3;
DE   AltName: Full=Forkhead box protein A3;
DE   AltName: Full=Transcription factor 3G;
DE            Short=TCF-3G;
GN   Name=FOXA3; Synonyms=HNF3G, TCF3G;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0001678; P:cellular glucose homeostasis; TAS:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048665; P:neuron fate specification; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010817; P:regulation of hormone levels; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXB2_HUMAN             Reviewed;         432 AA.
AC   Q5VYV0;
DE   RecName: Full=Forkhead box protein B2;
GN   Name=FOXB2;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048513; P:organ development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXB1_HUMAN             Reviewed;         325 AA.
AC   Q99853; O60652; O75917; Q14CL2;
DE   RecName: Full=Forkhead box protein B1;
DE   AltName: Full=Transcription factor FKH-5;
GN   Name=FOXB1; Synonyms=FKH5;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0007412; P:axon target recognition; ISS:UniProtKB.
DR   GO; GO:0061381; P:cell migration in diencephalon; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0061030; P:epithelial cell differentiation involved in mammary gland alveolus development; ISS:UniProtKB.
DR   GO; GO:0033504; P:floor plate development; ISS:UniProtKB.
DR   GO; GO:0021855; P:hypothalamus cell migration; ISS:UniProtKB.
DR   GO; GO:0061379; P:inferior colliculus development; ISS:UniProtKB.
DR   GO; GO:0007595; P:lactation; ISS:UniProtKB.
DR   GO; GO:0061377; P:mammary gland lobule development; ISS:UniProtKB.
DR   GO; GO:0021767; P:mammillary body development; ISS:UniProtKB.
DR   GO; GO:0061374; P:mammillothalamic axonal tract development; ISS:UniProtKB.
DR   GO; GO:0030901; P:midbrain development; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048513; P:organ development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0001756; P:somitogenesis; ISS:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0022029; P:telencephalon cell migration; ISS:UniProtKB.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0001655; P:urogenital system development; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; ISS:UniProtKB.
//
ID   FOXC1_HUMAN             Reviewed;         553 AA.
AC   Q12948; Q86UP7; Q9BYM1; Q9NUE5; Q9UDD0; Q9UP06;
DE   RecName: Full=Forkhead box protein C1;
DE   AltName: Full=Forkhead-related protein FKHL7;
DE   AltName: Full=Forkhead-related transcription factor 3;
DE            Short=FREAC-3;
GN   Name=FOXC1; Synonyms=FKHL7, FREAC3;
DR   GO; GO:0031490; F:chromatin DNA binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; IDA:MGI.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IDA:MGI.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0032808; P:lacrimal gland development; IEA:Ensembl.
DR   GO; GO:0001945; P:lymph vessel development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:1902257; P:negative regulation of apoptotic process involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IBA:RefGenome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0048341; P:paraxial mesoderm formation; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:Ensembl.
DR   GO; GO:0046620; P:regulation of organ growth; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
//
ID   FOXC2_HUMAN             Reviewed;         501 AA.
AC   Q99958; C6KMR9; Q14DA6;
DE   RecName: Full=Forkhead box protein C2;
DE   AltName: Full=Forkhead-related protein FKHL14;
DE   AltName: Full=Mesenchyme fork head protein 1;
DE            Short=MFH-1 protein;
DE   AltName: Full=Transcription factor FKH-14;
GN   Name=FOXC2; Synonyms=FKHL14, MFH1;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0048844; P:artery morphogenesis; IBA:RefGenome.
DR   GO; GO:0001974; P:blood vessel remodeling; IBA:RefGenome.
DR   GO; GO:0043010; P:camera-type eye development; IBA:RefGenome.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IBA:RefGenome.
DR   GO; GO:0030199; P:collagen fibril organization; IBA:RefGenome.
DR   GO; GO:0035050; P:embryonic heart tube development; IBA:RefGenome.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IBA:RefGenome.
DR   GO; GO:0072011; P:glomerular endothelium development; IEA:Ensembl.
DR   GO; GO:0072144; P:glomerular mesangial cell development; IEA:Ensembl.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IMP:DFLAT.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
DR   GO; GO:0007498; P:mesoderm development; NAS:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:1902257; P:negative regulation of apoptotic process involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IBA:RefGenome.
DR   GO; GO:0001503; P:ossification; IBA:RefGenome.
DR   GO; GO:0048343; P:paraxial mesodermal cell fate commitment; IBA:RefGenome.
DR   GO; GO:0001569; P:patterning of blood vessels; IBA:RefGenome.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:BHF-UCL.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035470; P:positive regulation of vascular wound healing; ISS:BHF-UCL.
DR   GO; GO:0050880; P:regulation of blood vessel size; IBA:RefGenome.
DR   GO; GO:0046620; P:regulation of organ growth; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0001657; P:ureteric bud development; IBA:RefGenome.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IBA:RefGenome.
//
ID   FOXD1_HUMAN             Reviewed;         465 AA.
AC   Q16676; Q12949;
DE   RecName: Full=Forkhead box protein D1;
DE   AltName: Full=Forkhead-related protein FKHL8;
DE   AltName: Full=Forkhead-related transcription factor 4;
DE            Short=FREAC-4;
GN   Name=FOXD1; Synonyms=FKHL8, FREAC4;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0060678; P:dichotomous subdivision of terminal units involved in ureteric bud branching; ISS:UniProtKB.
DR   GO; GO:0072213; P:metanephric capsule development; ISS:UniProtKB.
DR   GO; GO:0072267; P:metanephric capsule specification; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0090184; P:positive regulation of kidney development; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXD2_HUMAN             Reviewed;         495 AA.
AC   O60548; Q5SVZ3;
DE   RecName: Full=Forkhead box protein D2;
DE   AltName: Full=Forkhead-related protein FKHL17;
DE   AltName: Full=Forkhead-related transcription factor 9;
DE            Short=FREAC-9;
GN   Name=FOXD2; Synonyms=FKHL17, FREAC9;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXD3_HUMAN             Reviewed;         478 AA.
AC   Q9UJU5; Q9BYM2; Q9UDD1;
DE   RecName: Full=Forkhead box protein D3;
DE   AltName: Full=HNF3/FH transcription factor genesis;
GN   Name=FOXD3; Synonyms=HFH2;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001227; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0001892; P:embryonic placenta development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IBA:RefGenome.
//
ID   FOXD4_HUMAN             Reviewed;         439 AA.
AC   Q12950; B2RN05; B9EGL7; Q5VVK1; Q8WXT6;
DE   RecName: Full=Forkhead box protein D4;
DE   AltName: Full=Forkhead-related protein FKHL9;
DE   AltName: Full=Forkhead-related transcription factor 5;
DE            Short=FREAC-5;
DE   AltName: Full=Myeloid factor-alpha;
GN   Name=FOXD4; Synonyms=FKHL9, FOXD4A, FREAC5;
DR   GO; GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXE1_HUMAN             Reviewed;         373 AA.
AC   O00358; O75765; Q5T109; Q99526;
DE   RecName: Full=Forkhead box protein E1;
DE   AltName: Full=Forkhead box protein E2;
DE   AltName: Full=Forkhead-related protein FKHL15;
DE   AltName: Full=HFKH4;
DE   AltName: Full=HNF-3/fork head-like protein 5;
DE            Short=HFKL5;
DE   AltName: Full=Thyroid transcription factor 2;
DE            Short=TTF-2;
GN   Name=FOXE1; Synonyms=FKHL15, FOXE2, TITF2, TTF2;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0048562; P:embryonic organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060022; P:hard palate development; IMP:UniProtKB.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0060465; P:pharynx development; IEP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0060023; P:soft palate development; IMP:UniProtKB.
DR   GO; GO:0048538; P:thymus development; IEP:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IMP:UniProtKB.
DR   GO; GO:0006590; P:thyroid hormone generation; ISS:UniProtKB.
//
ID   FOXE3_HUMAN             Reviewed;         319 AA.
AC   Q13461; Q5SVY9; Q9NQV9;
DE   RecName: Full=Forkhead box protein E3;
DE   AltName: Full=Forkhead-related protein FKHL12;
DE   AltName: Full=Forkhead-related transcription factor 8;
DE            Short=FREAC-8;
GN   Name=FOXE3; Synonyms=FKHL12, FREAC8;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0048562; P:embryonic organ morphogenesis; IBA:RefGenome.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IBA:RefGenome.
DR   GO; GO:0060022; P:hard palate development; IBA:RefGenome.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0060023; P:soft palate development; IBA:RefGenome.
DR   GO; GO:0030878; P:thyroid gland development; IBA:RefGenome.
DR   GO; GO:0006590; P:thyroid hormone generation; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:MGI.
//
ID   FOXF1_HUMAN             Reviewed;         379 AA.
AC   Q12946; B2RAF4; Q5FWE5;
DE   RecName: Full=Forkhead box protein F1;
DE   AltName: Full=Forkhead-related activator 1;
DE            Short=FREAC-1;
DE   AltName: Full=Forkhead-related protein FKHL5;
DE   AltName: Full=Forkhead-related transcription factor 1;
GN   Name=FOXF1; Synonyms=FKHL5, FREAC1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IMP:DFLAT.
DR   GO; GO:0060446; P:branching involved in open tracheal system development; IMP:DFLAT.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; IMP:DFLAT.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0014822; P:detection of wounding; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IMP:DFLAT.
DR   GO; GO:0097070; P:ductus arteriosus closure; IMP:DFLAT.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IMP:DFLAT.
DR   GO; GO:0048613; P:embryonic ectodermal digestive tract morphogenesis; IMP:DFLAT.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0003197; P:endocardial cushion development; IMP:DFLAT.
DR   GO; GO:0061030; P:epithelial cell differentiation involved in mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0045198; P:establishment of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IMP:DFLAT.
DR   GO; GO:0001701; P:in utero embryonic development; IMP:DFLAT.
DR   GO; GO:0048371; P:lateral mesodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IMP:DFLAT.
DR   GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
DR   GO; GO:0060426; P:lung vasculature development; IMP:DFLAT.
DR   GO; GO:0090131; P:mesenchyme migration; IEA:Ensembl.
DR   GO; GO:0007494; P:midgut development; IMP:DFLAT.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; IMP:DFLAT.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043305; P:negative regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0031016; P:pancreas development; IMP:DFLAT.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0051150; P:regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0072001; P:renal system development; IMP:DFLAT.
DR   GO; GO:0030323; P:respiratory tube development; IMP:DFLAT.
DR   GO; GO:0060461; P:right lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0060438; P:trachea development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0072189; P:ureter development; IMP:DFLAT.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0060841; P:venous blood vessel development; IMP:DFLAT.
//
ID   FOXF2_HUMAN             Reviewed;         444 AA.
AC   Q12947; Q5TGJ1; Q9UQ85;
DE   RecName: Full=Forkhead box protein F2;
DE   AltName: Full=Forkhead-related activator 2;
DE            Short=FREAC-2;
DE   AltName: Full=Forkhead-related protein FKHL6;
DE   AltName: Full=Forkhead-related transcription factor 2;
GN   Name=FOXF2; Synonyms=FKHL6, FREAC2;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; NAS:UniProtKB.
DR   GO; GO:0042249; P:establishment of planar polarity of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0048806; P:genitalia development; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXG1_HUMAN             Reviewed;         489 AA.
AC   P55316; A6NFY2; P55315; Q14488; Q86XT7;
DE   RecName: Full=Forkhead box protein G1;
DE   AltName: Full=Brain factor 1;
DE            Short=BF-1;
DE            Short=BF1;
DE   AltName: Full=Brain factor 2;
DE            Short=BF-2;
DE            Short=BF2;
DE            Short=hBF-2;
DE   AltName: Full=Forkhead box protein G1A;
DE   AltName: Full=Forkhead box protein G1B;
DE   AltName: Full=Forkhead box protein G1C;
DE   AltName: Full=Forkhead-related protein FKHL1;
DE            Short=HFK1;
DE   AltName: Full=Forkhead-related protein FKHL2;
DE            Short=HFK2;
DE   AltName: Full=Forkhead-related protein FKHL3;
DE            Short=HFK3;
GN   Name=FOXG1;
GN   Synonyms=FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0016199; P:axon midline choice point recognition; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048664; P:neuron fate determination; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0021852; P:pyramidal neuron migration; IEA:Ensembl.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXH1_HUMAN             Reviewed;         365 AA.
AC   O75593; D3DWM4;
DE   RecName: Full=Forkhead box protein H1;
DE   AltName: Full=Forkhead activin signal transducer 1;
DE            Short=Fast-1;
DE            Short=hFAST-1;
DE   AltName: Full=Forkhead activin signal transducer 2;
DE            Short=Fast-2;
GN   Name=FOXH1; Synonyms=FAST1, FAST2;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.
DR   GO; GO:0070410; F:co-SMAD binding; IMP:BHF-UCL.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IMP:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:Ensembl.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0048318; P:axial mesoderm development; IBA:RefGenome.
DR   GO; GO:0001568; P:blood vessel development; IBA:RefGenome.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; IEA:Ensembl.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IBA:RefGenome.
DR   GO; GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; IBA:RefGenome.
DR   GO; GO:0021508; P:floor plate formation; IBA:RefGenome.
DR   GO; GO:0001947; P:heart looping; IBA:RefGenome.
DR   GO; GO:2000824; P:negative regulation of androgen receptor activity; IDA:BHF-UCL.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:1900164; P:nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; NAS:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0003139; P:secondary heart field specification; IEA:Ensembl.
DR   GO; GO:0010159; P:specification of organ position; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
//
ID   FOXI1_HUMAN             Reviewed;         378 AA.
AC   Q12951; Q14518; Q66SR7; Q8N6L8;
DE   RecName: Full=Forkhead box protein I1;
DE   AltName: Full=Forkhead-related protein FKHL10;
DE   AltName: Full=Forkhead-related transcription factor 6;
DE            Short=FREAC-6;
DE   AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 3;
DE            Short=HFH-3;
DE            Short=HNF-3/fork-head homolog 3;
GN   Name=FOXI1; Synonyms=FKHL10, FREAC6;
DR   GO; GO:0008301; F:DNA binding, bending; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXI2_HUMAN             Reviewed;         318 AA.
AC   Q6ZQN5;
DE   RecName: Full=Forkhead box protein I2;
GN   Name=FOXI2;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048513; P:organ development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXI3_HUMAN             Reviewed;         420 AA.
AC   A8MTJ6; B5RI09;
DE   RecName: Full=Forkhead box protein I3;
GN   Name=FOXI3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXJ2_HUMAN             Reviewed;         574 AA.
AC   Q9P0K8; A0AVK4; B2RMP3; Q96PS9; Q9NSN5;
DE   RecName: Full=Forkhead box protein J2;
DE   AltName: Full=Fork head homologous X;
GN   Name=FOXJ2; Synonyms=FHX;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXJ3_HUMAN             Reviewed;         622 AA.
AC   Q9UPW0; A7MBL7; A7MD18; D3DPW2; Q9NSS7;
DE   RecName: Full=Forkhead box protein J3;
GN   Name=FOXJ3; Synonyms=KIAA1041;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXJ1_HUMAN             Reviewed;         421 AA.
AC   Q92949; O00630;
DE   RecName: Full=Forkhead box protein J1;
DE   AltName: Full=Forkhead-related protein FKHL13;
DE   AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 4;
DE            Short=HFH-4;
GN   Name=FOXJ1; Synonyms=FKHL13, HFH4;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0007420; P:brain development; ISS:BHF-UCL.
DR   GO; GO:0002508; P:central tolerance induction; ISS:BHF-UCL.
DR   GO; GO:0042384; P:cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0060429; P:epithelium development; ISS:BHF-UCL.
DR   GO; GO:0035089; P:establishment of apical/basal cell polarity; ISS:BHF-UCL.
DR   GO; GO:0072016; P:glomerular parietal epithelial cell development; IEP:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; IBA:RefGenome.
DR   GO; GO:0006959; P:humoral immune response; ISS:BHF-UCL.
DR   GO; GO:0060972; P:left/right pattern formation; IBA:RefGenome.
DR   GO; GO:0050900; P:leukocyte migration; ISS:BHF-UCL.
DR   GO; GO:0060428; P:lung epithelium development; IEP:BHF-UCL.
DR   GO; GO:0035502; P:metanephric part of ureteric bud development; IEP:BHF-UCL.
DR   GO; GO:0050869; P:negative regulation of B cell activation; ISS:BHF-UCL.
DR   GO; GO:0002635; P:negative regulation of germinal center formation; ISS:BHF-UCL.
DR   GO; GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; ISS:BHF-UCL.
DR   GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0033085; P:negative regulation of T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007389; P:pattern specification process; ISS:BHF-UCL.
DR   GO; GO:0002897; P:positive regulation of central B cell tolerance induction; ISS:BHF-UCL.
DR   GO; GO:1901248; P:positive regulation of lung ciliated cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXK1_HUMAN             Reviewed;         733 AA.
AC   P85037;
DE   RecName: Full=Forkhead box protein K1;
DE   AltName: Full=Myocyte nuclear factor;
DE            Short=MNF;
GN   Name=FOXK1; Synonyms=MNF;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0000287; F:magnesium ion binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXK2_HUMAN             Reviewed;         660 AA.
AC   Q01167; A6NEP5; Q13622; Q13623; Q13624;
DE   RecName: Full=Forkhead box protein K2;
DE   AltName: Full=Cellular transcription factor ILF-1;
DE   AltName: Full=FOXK1;
DE   AltName: Full=Interleukin enhancer-binding factor 1;
GN   Name=FOXK2; Synonyms=ILF, ILF1;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXL1_HUMAN             Reviewed;         345 AA.
AC   Q12952; Q17RR1; Q9H242;
DE   RecName: Full=Forkhead box protein L1;
DE   AltName: Full=Forkhead-related protein FKHL11;
DE   AltName: Full=Forkhead-related transcription factor 7;
DE            Short=FREAC-7;
GN   Name=FOXL1; Synonyms=FKHL11, FREAC7;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0008301; F:DNA binding, bending; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0043010; P:camera-type eye development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007507; P:heart development; IMP:DFLAT.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0061146; P:Peyer's patch morphogenesis; IEA:Ensembl.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007495; P:visceral mesoderm-endoderm interaction involved in midgut development; ISS:UniProtKB.
//
ID   FOXL2_HUMAN             Reviewed;         376 AA.
AC   P58012; Q4ZGJ3;
DE   RecName: Full=Forkhead box protein L2;
GN   Name=FOXL2;
DR   GO; GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0030331; F:estrogen receptor binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IMP:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome.
DR   GO; GO:0002074; P:extraocular skeletal muscle development; IMP:UniProtKB.
DR   GO; GO:0019101; P:female somatic sex determination; IBA:RefGenome.
DR   GO; GO:0060014; P:granulosa cell differentiation; IEA:Ensembl.
DR   GO; GO:0042703; P:menstruation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IMP:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXM1_HUMAN             Reviewed;         763 AA.
AC   Q08050; O43258; O43259; O43260; Q4ZGG7; Q9BRL2;
DE   RecName: Full=Forkhead box protein M1;
DE   AltName: Full=Forkhead-related protein FKHL16;
DE   AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 11;
DE            Short=HFH-11;
DE            Short=HNF-3/fork-head homolog 11;
DE   AltName: Full=M-phase phosphoprotein 2;
DE   AltName: Full=MPM-2 reactive phosphoprotein 2;
DE   AltName: Full=Transcription factor Trident;
DE   AltName: Full=Winged-helix factor from INS-1 cells;
GN   Name=FOXM1; Synonyms=FKHL16, HFH11, MPP2, WIN;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; TAS:UniProtKB.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0001889; P:liver development; IBA:RefGenome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090344; P:negative regulation of cell aging; IMP:UniProtKB.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:2000781; P:positive regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0071156; P:regulation of cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0046578; P:regulation of Ras protein signal transduction; IMP:BHF-UCL.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:GOC.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0001570; P:vasculogenesis; IBA:RefGenome.
//
ID   FOXN1_HUMAN             Reviewed;         648 AA.
AC   O15353; B2R9Q7; O15352;
DE   RecName: Full=Forkhead box protein N1;
DE   AltName: Full=Winged-helix transcription factor nude;
GN   Name=FOXN1; Synonyms=RONU, WHN;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002260; P:lymphocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0035878; P:nail development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0033081; P:regulation of T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   FOXN2_HUMAN             Reviewed;         431 AA.
AC   P32314; Q15769; Q6P4Q2;
DE   RecName: Full=Forkhead box protein N2;
DE   AltName: Full=Human T-cell leukemia virus enhancer factor;
GN   Name=FOXN2; Synonyms=HTLF;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXN3_HUMAN             Reviewed;         490 AA.
AC   O00409; Q96II7; Q9UIE7;
DE   RecName: Full=Forkhead box protein N3;
DE   AltName: Full=Checkpoint suppressor 1;
GN   Name=FOXN3; Synonyms=C14orf116, CHES1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000077; P:DNA damage checkpoint; TAS:ProtInc.
DR   GO; GO:0000085; P:mitotic G2 phase; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXN4_HUMAN             Reviewed;         517 AA.
AC   Q96NZ1; Q6ZMR4; Q96NZ0;
DE   RecName: Full=Forkhead box protein N4;
GN   Name=FOXN4;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0035881; P:amacrine cell differentiation; ISS:UniProtKB.
DR   GO; GO:0036302; P:atrioventricular canal development; ISS:UniProtKB.
DR   GO; GO:0001947; P:heart looping; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008016; P:regulation of heart contraction; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060579; P:ventral spinal cord interneuron fate commitment; ISS:UniProtKB.
//
ID   FOXO1_HUMAN             Reviewed;         655 AA.
AC   Q12778; O43523; Q5VYC7; Q6NSK6;
DE   RecName: Full=Forkhead box protein O1;
DE   AltName: Full=Forkhead box protein O1A;
DE   AltName: Full=Forkhead in rhabdomyosarcoma;
GN   Name=FOXO1; Synonyms=FKHR, FOXO1A;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0001568; P:blood vessel development; IBA:RefGenome.
DR   GO; GO:0001678; P:cellular glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0070417; P:cellular response to cold; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0071732; P:cellular response to nitric oxide; ISS:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006473; P:protein acetylation; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0035947; P:regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; ISS:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
//
ID   FOXO3_HUMAN             Reviewed;         673 AA.
AC   O43524; E1P5E6; O15171; Q5T2I7; Q9BZ04;
DE   RecName: Full=Forkhead box protein O3;
DE   AltName: Full=AF6q21 protein;
DE   AltName: Full=Forkhead in rhabdomyosarcoma-like 1;
GN   Name=FOXO3; Synonyms=FKHRL1, FOXO3A;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0001547; P:antral ovarian follicle growth; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IBA:RefGenome.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0001544; P:initiation of primordial ovarian follicle growth; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.
DR   GO; GO:0006417; P:regulation of translation; IDA:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXO6_HUMAN             Reviewed;         492 AA.
AC   A8MYZ6;
DE   RecName: Full=Forkhead box protein O6;
GN   Name=FOXO6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXO4_HUMAN             Reviewed;         505 AA.
AC   P98177; B7WPJ7; O43821; Q13720; Q3KPF1; Q8TDK9;
DE   RecName: Full=Forkhead box protein O4;
DE   AltName: Full=Fork head domain transcription factor AFX1;
GN   Name=FOXO4; Synonyms=AFX, AFX1, MLLT7;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IMP:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IBA:RefGenome.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070317; P:negative regulation of G0 to G1 transition; IDA:UniProtKB.
DR   GO; GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   FOXP1_HUMAN             Reviewed;         677 AA.
AC   Q9H334; A3QVP8; B3KV70; G5E9V8; Q8NAN6; Q9BSG9; Q9H332; Q9H333;
AC   Q9P0R1;
DE   RecName: Full=Forkhead box protein P1;
GN   Name=FOXP1; ORFNames=HSPC215;
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0033152; P:immunoglobulin V(D)J recombination; IBA:RefGenome.
DR   GO; GO:0030324; P:lung development; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IBA:RefGenome.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IBA:RefGenome.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.
DR   GO; GO:0002329; P:pre-B cell differentiation; IBA:RefGenome.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.
DR   GO; GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXP2_HUMAN             Reviewed;         715 AA.
AC   O15409; A0AUV6; A4D0U8; A6NNW4; B4DLD9; Q6ZND1; Q75MJ3; Q8IZE0;
AC   Q8N0W2; Q8N6B7; Q8N6B8; Q8NFQ1; Q8NFQ2; Q8NFQ3; Q8NFQ4; Q8TD74;
DE   RecName: Full=Forkhead box protein P2;
DE   AltName: Full=CAG repeat protein 44;
DE   AltName: Full=Trinucleotide repeat-containing gene 10 protein;
GN   Name=FOXP2; Synonyms=CAGH44, TNRC10;
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0043010; P:camera-type eye development; IBA:RefGenome.
DR   GO; GO:0021757; P:caudate nucleus development; IMP:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; IBA:RefGenome.
DR   GO; GO:0021987; P:cerebral cortex development; IEP:BHF-UCL.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0040007; P:growth; IBA:RefGenome.
DR   GO; GO:0048286; P:lung alveolus development; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.
DR   GO; GO:0009791; P:post-embryonic development; IBA:RefGenome.
DR   GO; GO:0021758; P:putamen development; IMP:UniProtKB.
DR   GO; GO:0060013; P:righting reflex; IBA:RefGenome.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.
DR   GO; GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042297; P:vocal learning; IBA:RefGenome.
//
ID   FOXP4_HUMAN             Reviewed;         680 AA.
AC   Q8IVH2; Q5W098; Q7Z7F8; Q8IW55; Q96E19;
DE   RecName: Full=Forkhead box protein P4;
DE   AltName: Full=Fork head-related protein-like A;
GN   Name=FOXP4; Synonyms=FKHLA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0061140; P:lung secretory cell differentiation; IEA:Ensembl.
DR   GO; GO:1901250; P:negative regulation of lung goblet cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FOXQ1_HUMAN             Reviewed;         403 AA.
AC   Q9C009; Q9NS06;
DE   RecName: Full=Forkhead box protein Q1;
DE   AltName: Full=HNF-3/forkhead-like protein 1;
DE            Short=HFH-1;
DE   AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 1;
GN   Name=FOXQ1; Synonyms=HFH1;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXP3_HUMAN             Reviewed;         431 AA.
AC   Q9BZS1; A5HJT1; B7ZLG0; B9UN80; O60827; Q14DD8; Q4ZH51;
DE   RecName: Full=Forkhead box protein P3;
DE   AltName: Full=Scurfin;
GN   Name=FOXP3; Synonyms=IPEX; ORFNames=JM2;
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051059; F:NF-kappaB binding; NAS:UniProtKB.
DR   GO; GO:0051525; F:NFAT protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IBA:RefGenome.
DR   GO; GO:0001782; P:B cell homeostasis; IBA:RefGenome.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IBA:RefGenome.
DR   GO; GO:0002361; P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0033152; P:immunoglobulin V(D)J recombination; IBA:RefGenome.
DR   GO; GO:0030324; P:lung development; IBA:RefGenome.
DR   GO; GO:0002262; P:myeloid cell homeostasis; IBA:RefGenome.
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0002677; P:negative regulation of chronic inflammatory response; IBA:RefGenome.
DR   GO; GO:0032792; P:negative regulation of CREB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0042036; P:negative regulation of cytokine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IBA:RefGenome.
DR   GO; GO:0031064; P:negative regulation of histone deacetylation; IGI:BHF-UCL.
DR   GO; GO:0050777; P:negative regulation of immune response; IDA:UniProtKB.
DR   GO; GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IBA:RefGenome.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IDA:UniProtKB.
DR   GO; GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IDA:UniProtKB.
DR   GO; GO:0032713; P:negative regulation of interleukin-4 production; IDA:UniProtKB.
DR   GO; GO:0032714; P:negative regulation of interleukin-5 production; IBA:RefGenome.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IBA:RefGenome.
DR   GO; GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IBA:RefGenome.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0002725; P:negative regulation of T cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IBA:RefGenome.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IBA:RefGenome.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.
DR   GO; GO:0033092; P:positive regulation of immature T cell proliferation in thymus; IBA:RefGenome.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IBA:RefGenome.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0002851; P:positive regulation of peripheral T cell tolerance induction; IBA:RefGenome.
DR   GO; GO:0002669; P:positive regulation of T cell anergy; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032914; P:positive regulation of transforming growth factor beta1 production; IBA:RefGenome.
DR   GO; GO:0002329; P:pre-B cell differentiation; IBA:RefGenome.
DR   GO; GO:0048302; P:regulation of isotype switching to IgG isotypes; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; IDA:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; NAS:UniProtKB.
DR   GO; GO:0002456; P:T cell mediated immunity; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0002513; P:tolerance induction to self antigen; IBA:RefGenome.
//
ID   FOXR2_HUMAN             Reviewed;         311 AA.
AC   Q6PJQ5;
DE   RecName: Full=Forkhead box protein R2;
DE   AltName: Full=Forkhead box protein N6;
GN   Name=FOXR2; Synonyms=FOXN6;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048513; P:organ development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXR1_HUMAN             Reviewed;         292 AA.
AC   Q6PIV2; B0YJ15; Q86UT9; Q8IXX2;
DE   RecName: Full=Forkhead box protein R1;
DE   AltName: Full=Forkhead box protein N5;
GN   Name=FOXR1; Synonyms=FOXN5; ORFNames=DLNB13;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048513; P:organ development; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0009888; P:tissue development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FOXS1_HUMAN             Reviewed;         330 AA.
AC   O43638; Q96D28;
DE   RecName: Full=Forkhead box protein S1;
DE   AltName: Full=Forkhead-like 18 protein;
DE   AltName: Full=Forkhead-related transcription factor 10;
DE            Short=FREAC-10;
GN   Name=FOXS1; Synonyms=FKHL18, FREAC10;
DR   GO; GO:0031490; F:chromatin DNA binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048844; P:artery morphogenesis; IBA:RefGenome.
DR   GO; GO:0001568; P:blood vessel development; ISS:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IBA:RefGenome.
DR   GO; GO:0043010; P:camera-type eye development; IBA:RefGenome.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IBA:RefGenome.
DR   GO; GO:0030199; P:collagen fibril organization; IBA:RefGenome.
DR   GO; GO:0035050; P:embryonic heart tube development; IBA:RefGenome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0001946; P:lymphangiogenesis; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IBA:RefGenome.
DR   GO; GO:0007219; P:Notch signaling pathway; IBA:RefGenome.
DR   GO; GO:0001503; P:ossification; IBA:RefGenome.
DR   GO; GO:0048343; P:paraxial mesodermal cell fate commitment; IBA:RefGenome.
DR   GO; GO:0001569; P:patterning of blood vessels; IBA:RefGenome.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0050880; P:regulation of blood vessel size; IBA:RefGenome.
DR   GO; GO:0046620; P:regulation of organ growth; IBA:RefGenome.
DR   GO; GO:0001756; P:somitogenesis; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IBA:RefGenome.
//
ID   FP100_HUMAN             Reviewed;         881 AA.
AC   Q0VG06; A6NNM1; Q8N3F7; Q9BV13; Q9H6K7; Q9H7E8;
DE   RecName: Full=Fanconi anemia-associated protein of 100 kDa;
GN   Name=FAAP100; Synonyms=C17orf70;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   FPGT_HUMAN              Reviewed;         594 AA.
AC   O14772; A6NMH3; B4DRX2; B4E2Y7; E9PNQ2; Q8N5J7;
DE   RecName: Full=Fucose-1-phosphate guanylyltransferase;
DE            EC=2.7.7.30;
DE   AltName: Full=GDP-L-fucose diphosphorylase;
DE   AltName: Full=GDP-L-fucose pyrophosphorylase;
GN   Name=FPGT; Synonyms=GFPP;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0047341; F:fucose-1-phosphate guanylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006004; P:fucose metabolic process; TAS:ProtInc.
//
ID   FPPS_HUMAN              Reviewed;         419 AA.
AC   P14324; D3DV91; E9PCI9; Q96G29;
DE   RecName: Full=Farnesyl pyrophosphate synthase;
DE            Short=FPP synthase;
DE            Short=FPS;
DE            EC=2.5.1.10;
DE   AltName: Full=(2E,6E)-farnesyl diphosphate synthase;
DE   AltName: Full=Dimethylallyltranstransferase;
DE            EC=2.5.1.1;
DE   AltName: Full=Farnesyl diphosphate synthase;
DE   AltName: Full=Geranyltranstransferase;
GN   Name=FDPS; Synonyms=FPS, KIAA1293;
DR   GuidetoPHARMACOLOGY; 644; -.
DR   GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0045337; P:farnesyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0033384; P:geranyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   FPR1_HUMAN              Reviewed;         350 AA.
AC   P21462; Q14939; Q7Z6A4; Q86U52; Q9NS48;
DE   RecName: Full=fMet-Leu-Phe receptor;
DE            Short=fMLP receptor;
DE   AltName: Full=N-formyl peptide receptor;
DE            Short=FPR;
DE   AltName: Full=N-formylpeptide chemoattractant receptor;
GN   Name=FPR1;
DR   GuidetoPHARMACOLOGY; 222; -.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FPR2_HUMAN              Reviewed;         351 AA.
AC   P25090; A8K3E2;
DE   RecName: Full=N-formyl peptide receptor 2;
DE   AltName: Full=FMLP-related receptor I;
DE            Short=FMLP-R-I;
DE   AltName: Full=Formyl peptide receptor-like 1;
DE   AltName: Full=HM63;
DE   AltName: Full=Lipoxin A4 receptor;
DE            Short=LXA4 receptor;
DE   AltName: Full=RFP;
GN   Name=FPR2; Synonyms=FPRH1, FPRL1, LXA4R;
DR   GuidetoPHARMACOLOGY; 223; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
//
ID   FPR3_HUMAN              Reviewed;         353 AA.
AC   P25089;
DE   RecName: Full=N-formyl peptide receptor 3;
DE   AltName: Full=FMLP-related receptor II;
DE            Short=FMLP-R-II;
DE   AltName: Full=Formyl peptide receptor-like 2;
GN   Name=FPR3; Synonyms=FPRH1, FPRL2;
DR   GuidetoPHARMACOLOGY; 224; -.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FPRP_HUMAN              Reviewed;         879 AA.
AC   Q9P2B2; Q5VVU9; Q8N2K6;
DE   RecName: Full=Prostaglandin F2 receptor negative regulator;
DE   AltName: Full=CD9 partner 1;
DE            Short=CD9P-1;
DE   AltName: Full=Glu-Trp-Ile EWI motif-containing protein F;
DE            Short=EWI-F;
DE   AltName: Full=Prostaglandin F2-alpha receptor regulatory protein;
DE   AltName: Full=Prostaglandin F2-alpha receptor-associated protein;
DE   AltName: CD_antigen=CD315;
DE   Flags: Precursor;
GN   Name=PTGFRN; Synonyms=CD9P1, EWIF, FPRP, KIAA1436;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034389; P:lipid particle organization; IEA:Ensembl.
//
ID   FR1L4_HUMAN             Reviewed;        1794 AA.
AC   A9Z1Z3; Q9GZQ9; Q9H646; Q9H8L7;
DE   RecName: Full=Fer-1-like protein 4;
GN   Name=FER1L4; Synonyms=C20orf124;
//
ID   FR1L5_HUMAN             Reviewed;        2093 AA.
AC   A0AVI2; Q17RH2; Q6ZU24;
DE   RecName: Full=Fer-1-like protein 5;
GN   Name=FER1L5;
//
ID   FR1L6_HUMAN             Reviewed;        1857 AA.
AC   Q2WGJ9;
DE   RecName: Full=Fer-1-like protein 6;
GN   Name=FER1L6; Synonyms=C8orfK23;
//
ID   FR1OP_HUMAN             Reviewed;         399 AA.
AC   O95684; A8K1D1; B2R705; Q49AI0; Q5R3F6; Q96EW1;
DE   RecName: Full=FGFR1 oncogene partner;
GN   Name=FGFR1OP; Synonyms=FOP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0030292; F:protein tyrosine kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034453; P:microtubule anchoring; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
//
ID   FR8P1_HUMAN             Reviewed;         369 AA.
AC   Q9BZ68; A1A4X4;
DE   RecName: Full=Putative FERM domain-containing protein FRMD8P1;
DE   AltName: Full=FERM domain-containing 8 pseudogene 1;
GN   Name=FRMD8P1; ORFNames=FKSG43;
//
ID   FRAS1_HUMAN             Reviewed;        4008 AA.
AC   Q86XX4; A2RRR8; Q86UZ4; Q8N3U9; Q8NAU7; Q96JW7; Q9H6N9; Q9P228;
DE   RecName: Full=Extracellular matrix protein FRAS1;
DE   Flags: Precursor;
GN   Name=FRAS1; Synonyms=KIAA1500;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
//
ID   FRAT1_HUMAN             Reviewed;         279 AA.
AC   Q92837; Q5JTI1; Q8NE74; Q8TDW9;
DE   RecName: Full=Proto-oncogene FRAT1;
DE   AltName: Full=Frequently rearranged in advanced T-cell lymphomas 1;
DE            Short=FRAT-1;
GN   Name=FRAT1;
DR   GO; GO:0000578; P:embryonic axis specification; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   FRAT2_HUMAN             Reviewed;         233 AA.
AC   O75474; Q5JTI0; Q8WUL9; Q9BYG2;
DE   RecName: Full=GSK-3-binding protein FRAT2;
DE   AltName: Full=Frequently rearranged in advanced T-cell lymphomas 2;
DE            Short=FRAT-2;
GN   Name=FRAT2;
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   FRDA_HUMAN              Reviewed;         210 AA.
AC   Q16595; A8MXJ6; C9JJ89; O15545; O95656; Q15294; Q5VZ01;
DE   RecName: Full=Frataxin, mitochondrial;
DE            EC=1.16.3.1;
DE   AltName: Full=Friedreich ataxia protein;
DE            Short=Fxn;
DE   Contains:
DE     RecName: Full=Frataxin intermediate form;
DE              Short=i-FXN;
DE   Contains:
DE     RecName: Full=Frataxin(56-210);
DE     AltName: Full=m56-FXN;
DE   Contains:
DE     RecName: Full=Frataxin(78-210);
DE     AltName: Full=d-FXN;
DE     AltName: Full=m78-FXN;
DE   Contains:
DE     RecName: Full=Frataxin mature form;
DE     AltName: Full=Frataxin(81-210);
DE     AltName: Full=m81-FXN;
DE   Flags: Precursor;
GN   Name=FXN; Synonyms=FRDA, X25;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:BHF-UCL.
DR   GO; GO:0008199; F:ferric iron binding; IDA:BHF-UCL.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:BHF-UCL.
DR   GO; GO:0004322; F:ferroxidase activity; IDA:UniProtKB.
DR   GO; GO:0034986; F:iron chaperone activity; IDA:BHF-UCL.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0009060; P:aerobic respiration; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:Ensembl.
DR   GO; GO:0006783; P:heme biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0018283; P:iron incorporation into metallo-sulfur cluster; IDA:BHF-UCL.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0051349; P:positive regulation of lyase activity; IDA:UniProtKB.
DR   GO; GO:0048554; P:positive regulation of metalloenzyme activity; IMP:BHF-UCL.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IMP:BHF-UCL.
DR   GO; GO:0051347; P:positive regulation of transferase activity; IMP:BHF-UCL.
DR   GO; GO:0019230; P:proprioception; IEA:Ensembl.
DR   GO; GO:0016540; P:protein autoprocessing; IDA:BHF-UCL.
DR   GO; GO:0010722; P:regulation of ferrochelatase activity; IDA:BHF-UCL.
DR   GO; GO:0010039; P:response to iron ion; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FREM1_HUMAN             Reviewed;        2179 AA.
AC   Q5H8C1; B7ZBX4; Q5VV00; Q5VV01; Q6MZI4; Q8NEG9; Q96LI3;
DE   RecName: Full=FRAS1-related extracellular matrix protein 1;
DE   AltName: Full=Protein QBRICK;
DE   Flags: Precursor;
GN   Name=FREM1; Synonyms=C9orf143, C9orf145, C9orf154;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0097094; P:craniofacial suture morphogenesis; IMP:UniProtKB.
//
ID   FREM2_HUMAN             Reviewed;        3169 AA.
AC   Q5SZK8; Q4QQG1; Q5H9N8; Q5T6Q1; Q6N057; Q6ZSB4; Q7Z305; Q7Z341;
DE   RecName: Full=FRAS1-related extracellular matrix protein 2;
DE   AltName: Full=ECM3 homolog;
DE   Flags: Precursor;
GN   Name=FREM2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
//
ID   FREM3_HUMAN             Reviewed;        2139 AA.
AC   P0C091;
DE   RecName: Full=FRAS1-related extracellular matrix protein 3;
DE   Flags: Precursor;
GN   Name=FREM3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; NAS:BHF-UCL.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
//
ID   FRG1B_HUMAN             Reviewed;         182 AA.
AC   Q9BZ01; C4AME5;
DE   RecName: Full=Protein FRG1B;
GN   Name=FRG1B; Synonyms=C20orf80;
//
ID   FRG1_HUMAN              Reviewed;         258 AA.
AC   Q14331; A8K775;
DE   RecName: Full=Protein FRG1;
DE   AltName: Full=FSHD region gene 1 protein;
GN   Name=FRG1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   FRG2_HUMAN              Reviewed;         278 AA.
AC   Q64ET8;
DE   RecName: Full=Protein FRG2;
DE   AltName: Full=FSHD region gene 2 protein;
GN   Name=FRG2; Synonyms=FRG2A;
//
ID   FRG2B_HUMAN             Reviewed;         278 AA.
AC   Q96QU4; Q5VSQ1;
DE   RecName: Full=Protein FRG2-like-1;
DE   AltName: Full=FSHD region gene 2 protein family member B;
DE   AltName: Full=HSA10-FRG2;
GN   Name=FRG2B;
//
ID   FRG2C_HUMAN             Reviewed;         282 AA.
AC   A6NGY1;
DE   RecName: Full=Protein FRG2-like-2;
DE   AltName: Full=FSHD region gene 2 protein family member C;
DE   AltName: Full=HSA3-FRG2;
GN   Name=FRG2C;
//
ID   FRIH_HUMAN              Reviewed;         183 AA.
AC   P02794; B3KNR5; Q3KRA8; Q3SWW1;
DE   RecName: Full=Ferritin heavy chain;
DE            Short=Ferritin H subunit;
DE            EC=1.16.3.1;
DE   AltName: Full=Cell proliferation-inducing gene 15 protein;
DE   Contains:
DE     RecName: Full=Ferritin heavy chain, N-terminally processed;
GN   Name=FTH1; Synonyms=FTH, FTHL6; ORFNames=OK/SW-cl.84, PIG15;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0004322; F:ferroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005506; F:iron ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0006880; P:intracellular sequestering of iron ion; IDA:UniProtKB.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FRIL_HUMAN              Reviewed;         175 AA.
AC   P02792; B2R4B9; Q6IBT7; Q7Z2W1; Q86WI9; Q8WU07; Q96AU9; Q96CU0;
AC   Q9BTZ8;
DE   RecName: Full=Ferritin light chain;
DE            Short=Ferritin L subunit;
GN   Name=FTL;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0055072; P:iron ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FRITZ_HUMAN             Reviewed;         746 AA.
AC   O95876; Q53RW4; Q7Z2Z3;
DE   RecName: Full=WD repeat-containing and planar cell polarity effector protein fritz homolog;
DE            Short=hFRTZ;
DE   AltName: Full=Bardet-Biedl syndrome 15 protein;
DE   AltName: Full=WD repeat-containing and planar cell polarity effector protein;
GN   Name=WDPCP; Synonyms=BBS15, C2orf86, FRITZ;
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0016476; P:regulation of embryonic cell shape; ISS:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
DR   GO; GO:0032185; P:septin cytoskeleton organization; ISS:UniProtKB.
//
ID   FRK_HUMAN               Reviewed;         505 AA.
AC   P42685; Q13128; Q9NTR5;
DE   RecName: Full=Tyrosine-protein kinase FRK;
DE            EC=2.7.10.2;
DE   AltName: Full=FYN-related kinase;
DE   AltName: Full=Nuclear tyrosine protein kinase RAK;
DE   AltName: Full=Protein-tyrosine kinase 5;
GN   Name=FRK; Synonyms=PTK5, RAK;
DR   GuidetoPHARMACOLOGY; 2025; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   FRM4A_HUMAN             Reviewed;        1039 AA.
AC   Q9P2Q2; A7E2Y3; Q5T377;
DE   RecName: Full=FERM domain-containing protein 4A;
GN   Name=FRMD4A; Synonyms=FRMD4, KIAA1294;
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:Ensembl.
//
ID   FRM4B_HUMAN             Reviewed;        1034 AA.
AC   Q9Y2L6; Q8TAI3;
DE   RecName: Full=FERM domain-containing protein 4B;
DE   AltName: Full=GRP1-binding protein GRSP1;
GN   Name=FRMD4B; Synonyms=KIAA1013;
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:Ensembl.
//
ID   FRMD1_HUMAN             Reviewed;         549 AA.
AC   Q8N878; B2RNV8; B3KUM6; Q5SZU7; Q9UFB0;
DE   RecName: Full=FERM domain-containing protein 1;
GN   Name=FRMD1;
//
ID   FRMD6_HUMAN             Reviewed;         622 AA.
AC   Q96NE9; D3DSB9; Q5HYF2; Q8N2X1; Q8WUH7;
DE   RecName: Full=FERM domain-containing protein 6;
DE   AltName: Full=Willin;
GN   Name=FRMD6; Synonyms=C14orf31;
DR   GO; GO:0003383; P:apical constriction; IEA:Ensembl.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0032970; P:regulation of actin filament-based process; IEA:Ensembl.
//
ID   FRMD3_HUMAN             Reviewed;         597 AA.
AC   A2A2Y4; A8MQB0; B4DN14; Q53EP2; Q5JV59; Q5VZA1; Q86WP8; Q8IZ44;
AC   Q8N3Y5; Q8N9L2;
DE   RecName: Full=FERM domain-containing protein 3;
DE   AltName: Full=Band 4.1-like protein 4O;
DE   AltName: Full=Ovary type protein 4.1;
DE            Short=4.1O;
GN   Name=FRMD3; Synonyms=EPB41L4O;
//
ID   FRMD7_HUMAN             Reviewed;         714 AA.
AC   Q6ZUT3; C0LLJ3; Q5JX99;
DE   RecName: Full=FERM domain-containing protein 7;
GN   Name=FRMD7;
DR   GO; GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
//
ID   FRMD8_HUMAN             Reviewed;         464 AA.
AC   Q9BZ67; Q86V56; Q8NCB5;
DE   RecName: Full=FERM domain-containing protein 8;
GN   Name=FRMD8; ORFNames=FKSG44;
//
ID   FRMD5_HUMAN             Reviewed;         570 AA.
AC   Q7Z6J6; Q8NBG4;
DE   RecName: Full=FERM domain-containing protein 5;
GN   Name=FRMD5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   FRP2L_HUMAN             Reviewed;         320 AA.
AC   Q6IN97; B2RPG2; Q5RJ30;
DE   RecName: Full=Putative protein FRMPD2-like;
DE   AltName: Full=FERM and PDZ domain-containing protein 2 pseudogene 1;
DE   AltName: Full=PDZ domain-containing protein 5A;
GN   Name=FRMPD2P1; Synonyms=FRMPD2L1, PDZD5A, PDZK5A;
GN   and
GN   Name=FRMPD2P2; Synonyms=FRMPD2L2, PDZD5B, PDZK5B;
//
ID   FRPD1_HUMAN             Reviewed;        1578 AA.
AC   Q5SYB0; D3DRQ3; Q14C73; Q5HY96; Q9Y2H3;
DE   RecName: Full=FERM and PDZ domain-containing protein 1;
DE   AltName: Full=FERM domain-containing protein 2;
GN   Name=FRMPD1; Synonyms=FRMD2, KIAA0967;
//
ID   FRPD2_HUMAN             Reviewed;        1309 AA.
AC   Q68DX3; B7WNW0; B7ZML5; Q2VY07; Q6GMQ9; Q6ZN38; Q6ZWI2; Q8N5T9;
DE   RecName: Full=FERM and PDZ domain-containing protein 2;
DE   AltName: Full=PDZ domain-containing protein 4;
DE   AltName: Full=PDZ domain-containing protein 5C;
GN   Name=FRMPD2; Synonyms=PDZD5C, PDZK4, PDZK5C;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; IMP:UniProtKB.
//
ID   FRPD4_HUMAN             Reviewed;        1322 AA.
AC   Q14CM0; A8K0X9; O15032;
DE   RecName: Full=FERM and PDZ domain-containing protein 4;
DE   AltName: Full=PDZ domain-containing protein 10;
DE   AltName: Full=PSD-95-interacting regulator of spine morphogenesis;
DE            Short=Preso;
GN   Name=FRMPD4; Synonyms=KIAA0316, PDZD10, PDZK10;
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051835; P:positive regulation of synapse structural plasticity; IMP:UniProtKB.
//
ID   FRPD3_HUMAN             Reviewed;        1810 AA.
AC   Q5JV73; Q96JK8;
DE   RecName: Full=FERM and PDZ domain-containing protein 3;
GN   Name=FRMPD3; Synonyms=KIAA1817;
//
ID   FRRS1_HUMAN             Reviewed;         592 AA.
AC   Q6ZNA5; A6NLN7;
DE   RecName: Full=Ferric-chelate reductase 1;
DE            EC=1.-.-.-;
DE   AltName: Full=Stromal cell-derived receptor 2;
DE            Short=SDR-2;
GN   Name=FRRS1; Synonyms=SDFR2, SDR2;
DR   GO; GO:0000293; F:ferric-chelate reductase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   FRS1L_HUMAN             Reviewed;         344 AA.
AC   Q9P0K9; Q5T4G4;
DE   RecName: Full=DOMON domain-containing protein FRRS1L;
DE   AltName: Full=Brain protein CG-6;
DE   AltName: Full=Ferric-chelate reductase 1-like protein;
GN   Name=FRRS1L; Synonyms=C9orf4;
//
ID   FRS2_HUMAN              Reviewed;         508 AA.
AC   Q8WU20; B0LPF2; B2R684; O43558; Q7LDQ6;
DE   RecName: Full=Fibroblast growth factor receptor substrate 2;
DE            Short=FGFR substrate 2;
DE   AltName: Full=FGFR-signaling adaptor SNT;
DE   AltName: Full=Suc1-associated neurotrophic factor target 1;
DE            Short=SNT-1;
GN   Name=FRS2;
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IPI:MGI.
DR   GO; GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
DR   GO; GO:0019211; F:phosphatase activator activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; TAS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046619; P:optic placode formation involved in camera-type eye formation; IEA:Ensembl.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:UniProtKB.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   FRS3_HUMAN              Reviewed;         492 AA.
AC   O43559; Q5T3D5;
DE   RecName: Full=Fibroblast growth factor receptor substrate 3;
DE            Short=FGFR substrate 3;
DE   AltName: Full=FGFR-signaling adaptor SNT2;
DE   AltName: Full=Suc1-associated neurotrophic factor target 2;
DE            Short=SNT-2;
GN   Name=FRS3;
DR   GO; GO:0005104; F:fibroblast growth factor receptor binding; IPI:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   FRYL_HUMAN              Reviewed;        3013 AA.
AC   O94915; O95640; Q8WTZ5; Q9NT40;
DE   RecName: Full=Protein furry homolog-like;
DE   AltName: Full=ALL1-fused gene from chromosome 4p12 protein;
GN   Name=FRYL; Synonyms=AF4P12, KIAA0826;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FRY_HUMAN               Reviewed;        3013 AA.
AC   Q5TBA9; Q9Y3N6;
DE   RecName: Full=Protein furry homolog;
GN   Name=FRY; Synonyms=C13orf14;
//
ID   FS2P1_HUMAN             Reviewed;         482 AA.
AC   A8MWK0;
DE   RecName: Full=Putative fatty acid desaturase 2-like protein FADS2P1;
DE   AltName: Full=Fatty acid desaturase 2 pseudogene 1;
GN   Name=FADS2P1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR   GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   FSBP_HUMAN              Reviewed;         299 AA.
AC   O95073; Q8N4S5;
DE   RecName: Full=Fibrinogen silencer-binding protein;
GN   Name=FSBP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FSCB_HUMAN              Reviewed;         825 AA.
AC   Q5H9T9; Q5H9U7; Q86YI2; Q9H0J3;
DE   RecName: Full=Fibrous sheath CABYR-binding protein;
GN   Name=FSCB; Synonyms=C14orf155;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
//
ID   FSCN1_HUMAN             Reviewed;         493 AA.
AC   Q16658; A6NI89; B2RE97; Q96IC5; Q9BRF1;
DE   RecName: Full=Fascin;
DE   AltName: Full=55 kDa actin-bundling protein;
DE   AltName: Full=Singed-like protein;
DE   AltName: Full=p55;
GN   Name=FSCN1; Synonyms=FAN1, HSN, SNL;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0048870; P:cell motility; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
//
ID   FSCN2_HUMAN             Reviewed;         492 AA.
AC   O14926; A0AVC4; A8MRA6;
DE   RecName: Full=Fascin-2;
DE   AltName: Full=Retinal fascin;
GN   Name=FSCN2;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   FSD1L_HUMAN             Reviewed;         530 AA.
AC   Q9BXM9; A2A338; A6NKH7; B7Z5S6; B7Z5W3; Q5T879; Q5T880;
DE   RecName: Full=FSD1-like protein;
DE   AltName: Full=Coiled-coil domain-containing protein 10;
DE   AltName: Full=FSD1 N-terminal-like protein;
GN   Name=FSD1L; Synonyms=CCDC10, CSDUFD1, FSD1CL, FSD1NL;
//
ID   FSCN3_HUMAN             Reviewed;         498 AA.
AC   Q9NQT6; A4D0Z2; A6NLL7; B2RA62;
DE   RecName: Full=Fascin-3;
DE   AltName: Full=Testis fascin;
GN   Name=FSCN3;
//
ID   FSD1_HUMAN              Reviewed;         496 AA.
AC   Q9BTV5; B2RDT0; Q9BXN0; Q9HAG4;
DE   RecName: Full=Fibronectin type III and SPRY domain-containing protein 1;
DE   AltName: Full=MID1-related protein 1;
DE   AltName: Full=Microtubule-associated protein GLFND;
GN   Name=FSD1; Synonyms=GLFND, MIR1; ORFNames=VLP27;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   FSD2_HUMAN              Reviewed;         749 AA.
AC   A1L4K1; B3KVG1; B7ZM02;
DE   RecName: Full=Fibronectin type III and SPRY domain-containing protein 2;
DE   AltName: Full=SPRY domain-containing protein 1;
GN   Name=FSD2; Synonyms=SPRYD1;
//
ID   FSHB_HUMAN              Reviewed;         129 AA.
AC   P01225; A2TF08; A5JVV3; Q14D61;
DE   RecName: Full=Follitropin subunit beta;
DE   AltName: Full=Follicle-stimulating hormone beta subunit;
DE            Short=FSH-B;
DE            Short=FSH-beta;
DE   AltName: Full=Follitropin beta chain;
DE   Flags: Precursor;
GN   Name=FSHB;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0042699; P:follicle-stimulating hormone signaling pathway; IEA:Ensembl.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; NAS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0006701; P:progesterone biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0060011; P:Sertoli cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEP:BHF-UCL.
//
ID   FSHR_HUMAN              Reviewed;         695 AA.
AC   P23945; A8K947; G5CBS7; G5E967; J3KQ00; Q05AH0; Q16225; Q4QRJ3;
AC   Q4ZFZ2; Q53RW2;
DE   RecName: Full=Follicle-stimulating hormone receptor;
DE            Short=FSH-R;
DE   AltName: Full=Follitropin receptor;
DE   Flags: Precursor;
GN   Name=FSHR; Synonyms=LGR1;
DR   GuidetoPHARMACOLOGY; 253; -.
DR   GO; GO:0004963; F:follicle-stimulating hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0071711; P:basement membrane organization; IEA:Ensembl.
DR   GO; GO:0009992; P:cellular water homeostasis; IEA:Ensembl.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0008585; P:female gonad development; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008406; P:gonad development; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001545; P:primary ovarian follicle growth; IEA:Ensembl.
DR   GO; GO:0060408; P:regulation of acetylcholine metabolic process; IEA:Ensembl.
DR   GO; GO:0033044; P:regulation of chromosome organization; IEA:Ensembl.
DR   GO; GO:0032350; P:regulation of hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0010640; P:regulation of platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0003073; P:regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0060011; P:Sertoli cell proliferation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0035093; P:spermatogenesis, exchange of chromosomal proteins; IEA:Ensembl.
DR   GO; GO:0045056; P:transcytosis; IEA:Ensembl.
DR   GO; GO:0060065; P:uterus development; IEA:Ensembl.
//
ID   FSIP1_HUMAN             Reviewed;         581 AA.
AC   Q8NA03; Q6X2C8; Q86Y89;
DE   RecName: Full=Fibrous sheath-interacting protein 1;
GN   Name=FSIP1; ORFNames=HSD10;
//
ID   FSIP2_HUMAN             Reviewed;        6907 AA.
AC   Q5CZC0; Q53TL3; Q53TN5; Q5HYH2; Q6ZTZ5; Q6ZU14; Q6ZU21;
DE   RecName: Full=Fibrous sheath-interacting protein 2;
GN   Name=FSIP2;
//
ID   FSTL1_HUMAN             Reviewed;         308 AA.
AC   Q12841; D3DN90; Q549Z0;
DE   RecName: Full=Follistatin-related protein 1;
DE   AltName: Full=Follistatin-like protein 1;
DE   Flags: Precursor;
GN   Name=FSTL1; Synonyms=FRP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
//
ID   FSTL3_HUMAN             Reviewed;         263 AA.
AC   O95633; A8K7E3;
DE   RecName: Full=Follistatin-related protein 3;
DE   AltName: Full=Follistatin-like protein 3;
DE   AltName: Full=Follistatin-related gene protein;
DE   Flags: Precursor;
GN   Name=FSTL3; Synonyms=FLRG; ORFNames=UNQ674/PRO1308;
DR   GO; GO:0048185; F:activin binding; IPI:UniProtKB.
DR   GO; GO:0001968; F:fibronectin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0071248; P:cellular response to metal ion; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0090101; P:negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FSTL5_HUMAN             Reviewed;         847 AA.
AC   Q8N475; E9PCP6; Q9NSW7; Q9ULF7;
DE   RecName: Full=Follistatin-related protein 5;
DE   AltName: Full=Follistatin-like protein 5;
DE   Flags: Precursor;
GN   Name=FSTL5; Synonyms=KIAA1263;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   FSTL4_HUMAN             Reviewed;         842 AA.
AC   Q6MZW2; Q8TBU0; Q9UPU1;
DE   RecName: Full=Follistatin-related protein 4;
DE   AltName: Full=Follistatin-like protein 4;
DE   Flags: Precursor;
GN   Name=FSTL4; Synonyms=KIAA1061;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   FST_HUMAN               Reviewed;         344 AA.
AC   P19883; B5BU94; Q9BTH0;
DE   RecName: Full=Follistatin;
DE            Short=FS;
DE   AltName: Full=Activin-binding protein;
DE   Flags: Precursor;
GN   Name=FST;
DR   GO; GO:0048185; F:activin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IDA:UniProtKB.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0051798; P:positive regulation of hair follicle development; IDA:MGI.
//
ID   FTCD_HUMAN              Reviewed;         541 AA.
AC   O95954; B9EGD0; Q86V03; Q9HCT4; Q9HCT5; Q9HCT6; Q9UHJ2;
DE   RecName: Full=Formimidoyltransferase-cyclodeaminase;
DE   AltName: Full=Formiminotransferase-cyclodeaminase;
DE            Short=FTCD;
DE   AltName: Full=LCHC1;
DE   Includes:
DE     RecName: Full=Glutamate formimidoyltransferase;
DE              EC=2.1.2.5;
DE     AltName: Full=Glutamate formiminotransferase;
DE     AltName: Full=Glutamate formyltransferase;
DE   Includes:
DE     RecName: Full=Formimidoyltetrahydrofolate cyclodeaminase;
DE              EC=4.3.1.4;
DE     AltName: Full=Formiminotetrahydrofolate cyclodeaminase;
GN   Name=FTCD;
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0030412; F:formimidoyltetrahydrofolate cyclodeaminase activity; EXP:Reactome.
DR   GO; GO:0030409; F:glutamate formimidoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0006760; P:folic acid-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006548; P:histidine catabolic process; TAS:Reactome.
DR   GO; GO:0019556; P:histidine catabolic process to glutamate and formamide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019557; P:histidine catabolic process to glutamate and formate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
//
ID   FTMT_HUMAN              Reviewed;         242 AA.
AC   Q8N4E7;
DE   RecName: Full=Ferritin, mitochondrial;
DE            EC=1.16.3.1;
DE   Flags: Precursor;
GN   Name=FTMT;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0004322; F:ferroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0051349; P:positive regulation of lyase activity; IDA:BHF-UCL.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0051347; P:positive regulation of transferase activity; IDA:BHF-UCL.
//
ID   FTM_HUMAN               Reviewed;        1315 AA.
AC   Q68CZ1; A0PJ88; Q9Y2K8;
DE   RecName: Full=Protein fantom;
DE   AltName: Full=Nephrocystin-8;
DE   AltName: Full=RPGR-interacting protein 1-like protein;
DE            Short=RPGRIP1-like protein;
GN   Name=RPGRIP1L; Synonyms=FTM, KIAA1005, NPHP8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031870; F:thromboxane A2 receptor binding; IPI:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0022038; P:corpus callosum development; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0060322; P:head development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0021670; P:lateral ventricle development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0021532; P:neural tube patterning; IEA:Ensembl.
DR   GO; GO:0043584; P:nose development; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
//
ID   FTO_HUMAN               Reviewed;         505 AA.
AC   Q9C0B1; A2RUH1; B2RNS0; Q0P676; Q7Z785;
DE   RecName: Full=Alpha-ketoglutarate-dependent dioxygenase FTO;
DE            EC=1.14.11.-;
DE   AltName: Full=Fat mass and obesity-associated protein;
GN   Name=FTO; Synonyms=KIAA1752;
DR   GO; GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0035516; F:oxidative DNA demethylase activity; IDA:UniProtKB.
DR   GO; GO:0035515; F:oxidative RNA demethylase activity; IDA:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0080111; P:DNA demethylation; IDA:BHF-UCL.
DR   GO; GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.
DR   GO; GO:0035552; P:oxidative single-stranded DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0035553; P:oxidative single-stranded RNA demethylation; IDA:UniProtKB.
DR   GO; GO:0010883; P:regulation of lipid storage; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044065; P:regulation of respiratory system process; IEA:Ensembl.
DR   GO; GO:0070350; P:regulation of white fat cell proliferation; IEA:Ensembl.
DR   GO; GO:0042245; P:RNA repair; IDA:BHF-UCL.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
//
ID   FUBP1_HUMAN             Reviewed;         644 AA.
AC   Q96AE4; Q12828;
DE   RecName: Full=Far upstream element-binding protein 1;
DE            Short=FBP;
DE            Short=FUSE-binding protein 1;
DE   AltName: Full=DNA helicase V;
DE            Short=hDH V;
GN   Name=FUBP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   FUBP2_HUMAN             Reviewed;         711 AA.
AC   Q92945; O00301; Q59EZ9; Q5U4P6; Q9UNT5; Q9UQH5;
DE   RecName: Full=Far upstream element-binding protein 2;
DE            Short=FUSE-binding protein 2;
DE   AltName: Full=KH type-splicing regulatory protein;
DE            Short=KSRP;
DE   AltName: Full=p75;
GN   Name=KHSRP; Synonyms=FUBP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FUBP3_HUMAN             Reviewed;         572 AA.
AC   Q96I24; A3KFK8; A3KFL0; Q92946; Q9BVB6;
DE   RecName: Full=Far upstream element-binding protein 3;
DE            Short=FUSE-binding protein 3;
GN   Name=FUBP3; Synonyms=FBP3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   FUCM_HUMAN              Reviewed;         154 AA.
AC   A2VDF0; A1L300; Q5VWY2; Q5VWY3; Q6ZPD2;
DE   RecName: Full=Fucose mutarotase;
DE            EC=5.1.3.n2;
GN   Name=FUOM; Synonyms=C10orf125;
DR   GO; GO:0042806; F:fucose binding; ISS:UniProtKB.
DR   GO; GO:0016857; F:racemase and epimerase activity, acting on carbohydrates and derivatives; ISS:UniProtKB.
DR   GO; GO:0006004; P:fucose metabolic process; ISS:UniProtKB.
//
ID   FUCO2_HUMAN             Reviewed;         467 AA.
AC   Q9BTY2; Q7Z6Y2; Q8NBK4;
DE   RecName: Full=Plasma alpha-L-fucosidase;
DE            EC=3.2.1.51;
DE   AltName: Full=Alpha-L-fucoside fucohydrolase 2;
DE            Short=Alpha-L-fucosidase 2;
DE   Flags: Precursor;
GN   Name=FUCA2; ORFNames=PSEC0151, UNQ227/PRO260;
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IDA:UniProt.
DR   GO; GO:0042806; F:fucose binding; IBA:RefGenome.
DR   GO; GO:0006004; P:fucose metabolic process; IDA:UniProt.
DR   GO; GO:0016139; P:glycoside catabolic process; IDA:UniProt.
DR   GO; GO:2000535; P:regulation of entry of bacterium into host cell; IMP:UniProt.
DR   GO; GO:0009617; P:response to bacterium; IMP:UniProt.
//
ID   FUCO_HUMAN              Reviewed;         466 AA.
AC   P04066; Q14334; Q14335; Q3LID0; Q8NAC2;
DE   RecName: Full=Tissue alpha-L-fucosidase;
DE            EC=3.2.1.51;
DE   AltName: Full=Alpha-L-fucosidase I;
DE   AltName: Full=Alpha-L-fucoside fucohydrolase 1;
DE            Short=Alpha-L-fucosidase 1;
DE   Flags: Precursor;
GN   Name=FUCA1; ORFNames=Nbla10230;
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; TAS:UniProtKB.
DR   GO; GO:0042806; F:fucose binding; IBA:RefGenome.
DR   GO; GO:0006004; P:fucose metabolic process; IDA:UniProt.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; NAS:UniProtKB.
DR   GO; GO:0016139; P:glycoside catabolic process; IDA:UniProt.
//
ID   FUCT1_HUMAN             Reviewed;         364 AA.
AC   Q96A29; B2RDB2; Q9BV76; Q9NUJ8;
DE   RecName: Full=GDP-fucose transporter 1;
DE   AltName: Full=Solute carrier family 35 member C1;
GN   Name=SLC35C1; Synonyms=FUCT1;
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0030259; P:lipid glycosylation; IEA:Ensembl.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FUK_HUMAN               Reviewed;        1084 AA.
AC   Q8N0W3; Q5PSM3; Q5XKL6; Q6ZRA0; Q96MT9;
DE   RecName: Full=L-fucose kinase;
DE            Short=Fucokinase;
DE            EC=2.7.1.52;
GN   Name=FUK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050201; F:fucokinase activity; NAS:UniProtKB.
//
ID   FUMH_HUMAN              Reviewed;         510 AA.
AC   P07954;
DE   RecName: Full=Fumarate hydratase, mitochondrial;
DE            Short=Fumarase;
DE            EC=4.2.1.2;
DE   Flags: Precursor;
GN   Name=FH;
DR   GO; GO:0004333; F:fumarate hydratase activity; EXP:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006106; P:fumarate metabolic process; TAS:ProtInc.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   FUND1_HUMAN             Reviewed;         155 AA.
AC   Q8IVP5;
DE   RecName: Full=FUN14 domain-containing protein 1;
GN   Name=FUNDC1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000422; P:mitochondrion degradation; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
//
ID   FUND2_HUMAN             Reviewed;         189 AA.
AC   Q9BWH2; B2R7W5; D3DWY5; Q8NHX8; Q9H2I6;
DE   RecName: Full=FUN14 domain-containing protein 2;
DE   AltName: Full=Cervical cancer proto-oncogene 3 protein;
DE            Short=HCC-3;
DE   AltName: Full=Hepatitis C virus core-binding protein 6;
GN   Name=FUNDC2; Synonyms=HCBP6; ORFNames=DC44, HCC3, PD03104;
//
ID   FURIN_HUMAN             Reviewed;         794 AA.
AC   P09958; Q14336; Q6LBS3; Q9UCZ5;
DE   RecName: Full=Furin;
DE            EC=3.4.21.75;
DE   AltName: Full=Dibasic-processing enzyme;
DE   AltName: Full=Paired basic amino acid residue-cleaving enzyme;
DE            Short=PACE;
DE   Flags: Precursor;
GN   Name=FURIN; Synonyms=FUR, PACE, PCSK3;
DR   GuidetoPHARMACOLOGY; 2366; -.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; IDA:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0032804; P:negative regulation of low-density lipoprotein particle receptor catabolic process; IDA:HGNC.
DR   GO; GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:BHF-UCL.
DR   GO; GO:0032455; P:nerve growth factor processing; TAS:Reactome.
DR   GO; GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IC:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016485; P:protein processing; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
DR   GO; GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0032940; P:secretion by cell; IDA:BHF-UCL.
DR   GO; GO:0006465; P:signal peptide processing; IDA:HGNC.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; IEP:BHF-UCL.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   FUS_HUMAN               Reviewed;         526 AA.
AC   P35637; Q9H4A8;
DE   RecName: Full=RNA-binding protein FUS;
DE   AltName: Full=75 kDa DNA-pairing protein;
DE   AltName: Full=Oncogene FUS;
DE   AltName: Full=Oncogene TLS;
DE   AltName: Full=POMp75;
DE   AltName: Full=Translocated in liposarcoma protein;
GN   Name=FUS; Synonyms=TLS;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   FUT10_HUMAN             Reviewed;         479 AA.
AC   Q6P4F1; A8KAC8; Q70GG3; Q8IVI6; Q8IVI7; Q8IVJ3; Q8TE43; Q9BSR3;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 10;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase X;
DE            Short=Fuc-TX;
DE            Short=FucT-X;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase 10;
DE            Short=Fucosyltransferase 10;
GN   Name=FUT10;
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; NAS:UniProtKB.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; NAS:UniProtKB.
DR   GO; GO:0042060; P:wound healing; NAS:UniProtKB.
//
ID   FUT11_HUMAN             Reviewed;         492 AA.
AC   Q495W5; Q495W7; Q8IYE4;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 11;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase XI;
DE            Short=Fuc-TXI;
DE            Short=FucT-XI;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase 11;
DE            Short=Fucosyltransferase 11;
GN   Name=FUT11;
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   FUT1_HUMAN              Reviewed;         365 AA.
AC   P19526; O14505; O14506; O14507;
DE   RecName: Full=Galactoside 2-alpha-L-fucosyltransferase 1;
DE            EC=2.4.1.69;
DE   AltName: Full=Alpha(1,2)FT 1;
DE   AltName: Full=Blood group H alpha 2-fucosyltransferase;
DE   AltName: Full=Fucosyltransferase 1;
DE   AltName: Full=GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1;
GN   Name=FUT1; Synonyms=H, HSC;
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008107; F:galactoside 2-alpha-L-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUT2_HUMAN              Reviewed;         343 AA.
AC   Q10981; Q0VAG5; Q14338; Q5D0G2;
DE   RecName: Full=Galactoside 2-alpha-L-fucosyltransferase 2;
DE            EC=2.4.1.69;
DE   AltName: Full=Alpha(1,2)FT 2;
DE   AltName: Full=Fucosyltransferase 2;
DE   AltName: Full=GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2;
DE   AltName: Full=SE2;
DE   AltName: Full=Secretor blood group alpha-2-fucosyltransferase;
DE   AltName: Full=Secretor factor;
DE            Short=Se;
GN   Name=FUT2; Synonyms=SEC2;
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008107; F:galactoside 2-alpha-L-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUT3_HUMAN              Reviewed;         361 AA.
AC   P21217; B5U7U9; B5U7V0; Q32NE7; Q99448; Q99449;
DE   RecName: Full=Galactoside 3(4)-L-fucosyltransferase;
DE            EC=2.4.1.65;
DE   AltName: Full=Blood group Lewis alpha-4-fucosyltransferase;
DE            Short=Lewis FT;
DE   AltName: Full=Fucosyltransferase 3;
DE   AltName: Full=Fucosyltransferase III;
DE            Short=FucT-III;
GN   Name=FUT3; Synonyms=FT3B, LE;
DR   GO; GO:0017060; F:3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0008417; F:fucosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0009988; P:cell-cell recognition; IC:BHF-UCL.
DR   GO; GO:0036065; P:fucosylation; IDA:GOC.
DR   GO; GO:0043413; P:macromolecule glycosylation; IDA:BHF-UCL.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   FUT4_HUMAN              Reviewed;         530 AA.
AC   P22083; B2RMS0;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 4;
DE            EC=2.4.1.-;
DE   AltName: Full=ELAM-1 ligand fucosyltransferase;
DE   AltName: Full=Fucosyltransferase 4;
DE   AltName: Full=Fucosyltransferase IV;
DE            Short=Fuc-TIV;
DE            Short=FucT-IV;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase;
GN   Name=FUT4; Synonyms=ELFT, FCT3A;
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUT5_HUMAN              Reviewed;         374 AA.
AC   Q11128; A8K4X2;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 5;
DE            EC=2.4.1.65;
DE   AltName: Full=Fucosyltransferase 5;
DE   AltName: Full=Fucosyltransferase V;
DE            Short=Fuc-TV;
DE            Short=FucT-V;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase;
GN   Name=FUT5;
DR   GO; GO:0017060; F:3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUT6_HUMAN              Reviewed;         359 AA.
AC   P51993; A6NEX0; D6W637; Q9UND8;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 6;
DE            EC=2.4.1.65;
DE   AltName: Full=Fucosyltransferase 6;
DE   AltName: Full=Fucosyltransferase VI;
DE            Short=Fuc-TVI;
DE            Short=FucT-VI;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase;
GN   Name=FUT6; Synonyms=FCT3A;
DR   GO; GO:0017060; F:3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUT7_HUMAN              Reviewed;         342 AA.
AC   Q11130; B2R7U7; Q6DK54;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 7;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase 7;
DE   AltName: Full=Fucosyltransferase VII;
DE            Short=Fuc-TVII;
DE            Short=FucT-VII;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase;
DE   AltName: Full=Selectin ligand synthase;
GN   Name=FUT7;
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0002361; P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0002522; P:leukocyte migration involved in immune response; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUT8_HUMAN              Reviewed;         575 AA.
AC   Q9BYC5; B4DFS7; G3V5N0; O00235; Q8IUA5; Q9BYC6; Q9P2U5; Q9P2U6;
DE   RecName: Full=Alpha-(1,6)-fucosyltransferase;
DE            Short=Alpha1-6FucT;
DE            EC=2.4.1.68;
DE   AltName: Full=Fucosyltransferase 8;
DE   AltName: Full=GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase;
DE   AltName: Full=GDP-fucose--glycoprotein fucosyltransferase;
DE   AltName: Full=Glycoprotein 6-alpha-L-fucosyltransferase;
GN   Name=FUT8;
DR   GO; GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0046368; P:GDP-L-fucose metabolic process; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0036071; P:N-glycan fucosylation; IDA:GOC.
DR   GO; GO:0006491; P:N-glycan processing; TAS:UniProtKB.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.
DR   GO; GO:0006487; P:protein N-linked glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IDA:UniProtKB.
DR   GO; GO:0043112; P:receptor metabolic process; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   FUT9_HUMAN              Reviewed;         359 AA.
AC   Q9Y231; Q5T0W4;
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 9;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase 9;
DE   AltName: Full=Fucosyltransferase IX;
DE            Short=Fuc-TIX;
DE            Short=FucT-IX;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase;
GN   Name=FUT9;
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008417; F:fucosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0036065; P:fucosylation; TAS:GOC.
DR   GO; GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; TAS:UniProtKB.
//
ID   FUZZY_HUMAN             Reviewed;         418 AA.
AC   Q9BT04; B2RD86; B5MDH0; Q6PJY0; Q9H613;
DE   RecName: Full=Protein fuzzy homolog;
GN   Name=FUZ; Synonyms=FY;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0010172; P:embryonic body morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021513; P:spinal cord dorsal/ventral patterning; IEA:Ensembl.
//
ID   FWCH1_HUMAN             Reviewed;         716 AA.
AC   Q4VC44; D3DUA1; Q6ZSQ1; Q8WV62; Q9BQG6; Q9BUS5; Q9HCM0;
DE   RecName: Full=FLYWCH-type zinc finger-containing protein 1;
GN   Name=FLYWCH1; Synonyms=KIAA1552;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   FWCH2_HUMAN             Reviewed;         140 AA.
AC   Q96CP2;
DE   RecName: Full=FLYWCH family member 2;
GN   Name=FLYWCH2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   FX4L2_HUMAN             Reviewed;         416 AA.
AC   Q6VB85;
DE   RecName: Full=Forkhead box protein D4-like 2;
DE            Short=FOXD4-like 2;
GN   Name=FOXD4L2;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FX4L3_HUMAN             Reviewed;         417 AA.
AC   Q6VB84; Q5JTX9;
DE   RecName: Full=Forkhead box protein D4-like 3;
DE            Short=FOXD4-like 3;
GN   Name=FOXD4L3;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FX4L4_HUMAN             Reviewed;         416 AA.
AC   Q8WXT5; Q5RIB4;
DE   RecName: Full=Forkhead box protein D4-like 4;
DE            Short=FOXD4-like 4;
DE   AltName: Full=Forkhead box protein D4B;
DE   AltName: Full=Myeloid factor-gamma;
GN   Name=FOXD4L4; Synonyms=FOXD4B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   FX4L1_HUMAN             Reviewed;         408 AA.
AC   Q9NU39; B3KWN1; B9EGF3;
DE   RecName: Full=Forkhead box protein D4-like 1;
DE            Short=FOXD4-like 1;
GN   Name=FOXD4L1;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FX4L5_HUMAN             Reviewed;         416 AA.
AC   Q5VV16;
DE   RecName: Full=Forkhead box protein D4-like 5;
DE            Short=FOXD4-like 5;
GN   Name=FOXD4L5;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FX4L6_HUMAN             Reviewed;         417 AA.
AC   Q3SYB3; B2RPC4; Q4V336;
DE   RecName: Full=Forkhead box protein D4-like 6;
DE            Short=FOXD4-like 6;
GN   Name=FOXD4L6;
DR   GO; GO:0008301; F:DNA binding, bending; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IBA:RefGenome.
DR   GO; GO:0051216; P:cartilage development; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0048484; P:enteric nervous system development; IBA:RefGenome.
DR   GO; GO:0050935; P:iridophore differentiation; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IBA:RefGenome.
DR   GO; GO:0048937; P:lateral line nerve glial cell development; IBA:RefGenome.
DR   GO; GO:0030318; P:melanocyte differentiation; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0007389; P:pattern specification process; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0048485; P:sympathetic nervous system development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   FXDC2_HUMAN             Reviewed;         333 AA.
AC   Q96IV6; Q9BSX6; Q9H8C7;
DE   RecName: Full=Fatty acid hydroxylase domain-containing protein 2;
GN   Name=FAXDC2; Synonyms=C5orf4;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
//
ID   FXL12_HUMAN             Reviewed;         326 AA.
AC   Q9NXK8; B3KSJ8; Q9H5K4;
DE   RecName: Full=F-box/LRR-repeat protein 12;
DE   AltName: Full=F-box and leucine-rich repeat protein 12;
DE   AltName: Full=F-box protein FBL12;
GN   Name=FBXL12; Synonyms=FBL12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   FXL13_HUMAN             Reviewed;         735 AA.
AC   Q8NEE6; C9J565; C9J566; Q6UVW7; Q6UVW8; Q75MN5; Q86UJ5; Q8N7Y4;
AC   Q8TCL2; Q8WUF9; Q8WUG0;
DE   RecName: Full=F-box/LRR-repeat protein 13;
DE   AltName: Full=F-box and leucine-rich repeat protein 13;
GN   Name=FBXL13; Synonyms=FBL13;
//
ID   FXL14_HUMAN             Reviewed;         418 AA.
AC   Q8N1E6;
DE   RecName: Full=F-box/LRR-repeat protein 14;
DE   AltName: Full=F-box and leucine-rich repeat protein 14;
GN   Name=FBXL14; Synonyms=FBL14;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FXL15_HUMAN             Reviewed;         300 AA.
AC   Q9H469; A1L4J8; B1AKX8; B1AKX9; B1AKY0; B1AKY1; C9JWA4; Q0D2Q3;
AC   Q49AL7; Q5JWA5;
DE   RecName: Full=F-box/LRR-repeat protein 15;
DE   AltName: Full=F-box only protein 37;
GN   Name=FBXL15; Synonyms=FBXO37;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; ISS:UniProtKB.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   FXL16_HUMAN             Reviewed;         479 AA.
AC   Q8N461; D3DU60; Q2MHR2; Q96S14; Q9UJI0;
DE   RecName: Full=F-box/LRR-repeat protein 16;
DE   AltName: Full=F-box and leucine-rich repeat protein 16;
GN   Name=FBXL16; Synonyms=C16orf22, FBL16;
//
ID   FXL17_HUMAN             Reviewed;         701 AA.
AC   Q9UF56; A1A4E3;
DE   RecName: Full=F-box/LRR-repeat protein 17;
DE   AltName: Full=F-box and leucine-rich repeat protein 17;
DE   AltName: Full=F-box only protein 13;
GN   Name=FBXL17; Synonyms=FBL17, FBX13, FBXO13;
//
ID   FXL18_HUMAN             Reviewed;         805 AA.
AC   Q96ME1; Q9BR90; Q9BTC7; Q9HAK7;
DE   RecName: Full=F-box/LRR-repeat protein 18;
DE   AltName: Full=F-box and leucine-rich repeat protein 18;
GN   Name=FBXL18; Synonyms=FBL18;
//
ID   FXL19_HUMAN             Reviewed;         694 AA.
AC   Q6PCT2; A8MT10; Q8N789; Q9NT14;
DE   RecName: Full=F-box/LRR-repeat protein 19;
DE   AltName: Full=F-box and leucine-rich repeat protein 19;
GN   Name=FBXL19; Synonyms=FBL19;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:MGI.
//
ID   FXL20_HUMAN             Reviewed;         436 AA.
AC   Q96IG2; A8K729; Q38J52;
DE   RecName: Full=F-box/LRR-repeat protein 20;
DE   AltName: Full=F-box and leucine-rich repeat protein 20;
DE   AltName: Full=F-box/LRR-repeat protein 2-like;
GN   Name=FBXL20; Synonyms=FBL2;
//
ID   FXL21_HUMAN             Reviewed;         434 AA.
AC   Q9UKT6;
DE   RecName: Full=F-box/LRR-repeat protein 21;
DE   AltName: Full=F-box and leucine-rich repeat protein 21;
DE   AltName: Full=F-box and leucine-rich repeat protein 3B;
DE   AltName: Full=F-box/LRR-repeat protein 3B;
GN   Name=FBXL21; Synonyms=FBL21, FBL3, FBXL3B, FBXL3P;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
//
ID   FXL22_HUMAN             Reviewed;         247 AA.
AC   Q6P050;
DE   RecName: Full=F-box and leucine-rich protein 22;
GN   Name=FBXL22;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   FXR1_HUMAN              Reviewed;         621 AA.
AC   P51114; A8K9B8; Q7Z450; Q8N6R8;
DE   RecName: Full=Fragile X mental retardation syndrome-related protein 1;
DE            Short=hFXR1p;
GN   Name=FXR1;
DR   GO; GO:0002151; F:G-quadruplex RNA binding; IEA:Ensembl.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:Ensembl.
//
ID   FXR2_HUMAN              Reviewed;         673 AA.
AC   P51116; B2R9M2; D3DTQ1; Q86V09; Q8WUM2;
DE   RecName: Full=Fragile X mental retardation syndrome-related protein 2;
GN   Name=FXR2; Synonyms=FMR1L2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
//
ID   FXRD1_HUMAN             Reviewed;         486 AA.
AC   Q96CU9; B3KN84; B4DHU2; Q71MG0; Q9BU39; Q9UKY9;
DE   RecName: Full=FAD-dependent oxidoreductase domain-containing protein 1;
DE            EC=1.-.-.-;
GN   Name=FOXRED1; ORFNames=FP634;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   FXRD2_HUMAN             Reviewed;         684 AA.
AC   Q8IWF2; B2RDI4; Q8N378; Q96BD1; Q9H5L5; Q9H6M8;
DE   RecName: Full=FAD-dependent oxidoreductase domain-containing protein 2;
DE   AltName: Full=Endoplasmic reticulum flavoprotein associated with degradation;
DE   Flags: Precursor;
GN   Name=FOXRED2; Synonyms=ERFAD;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   FXYD3_HUMAN             Reviewed;          87 AA.
AC   Q14802; A6NDE0; C9JDU2; F5H174; F8WB34; Q13211; Q6IB59;
DE   RecName: Full=FXYD domain-containing ion transport regulator 3;
DE   AltName: Full=Chloride conductance inducer protein Mat-8;
DE   AltName: Full=Mammary tumor 8 kDa protein;
DE   AltName: Full=Phospholemman-like;
DE   Flags: Precursor;
GN   Name=FXYD3; Synonyms=MAT8, PLML;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FXYD4_HUMAN             Reviewed;          89 AA.
AC   P59646; Q6UWZ1; Q7Z4M5;
DE   RecName: Full=FXYD domain-containing ion transport regulator 4;
DE   Flags: Precursor;
GN   Name=FXYD4; ORFNames=UNQ526/PRO1069;
DR   GO; GO:0005267; F:potassium channel activity; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FXYD5_HUMAN             Reviewed;         178 AA.
AC   Q96DB9; B7WNZ8; Q6UW44; Q9HC34; Q9P039;
DE   RecName: Full=FXYD domain-containing ion transport regulator 5;
DE   AltName: Full=Dysadherin;
DE   Flags: Precursor;
GN   Name=FXYD5; Synonyms=DYSAD, IWU1; ORFNames=HSPC113, UNQ2561/PRO6241;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0045296; F:cadherin binding; IDA:UniProtKB.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0030033; P:microvillus assembly; NAS:UniProtKB.
DR   GO; GO:0046588; P:negative regulation of calcium-dependent cell-cell adhesion; NAS:UniProtKB.
//
ID   FXYD6_HUMAN             Reviewed;          95 AA.
AC   Q9H0Q3; A8K0R4; J3QLD2; Q6FIG9; Q6UW52;
DE   RecName: Full=FXYD domain-containing ion transport regulator 6;
DE   AltName: Full=Phosphohippolin;
DE   Flags: Precursor;
GN   Name=FXYD6; ORFNames=UNQ521/PRO1056;
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FXYD7_HUMAN             Reviewed;          80 AA.
AC   P58549;
DE   RecName: Full=FXYD domain-containing ion transport regulator 7;
GN   Name=FXYD7;
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0043269; P:regulation of ion transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   FXYD8_HUMAN             Reviewed;          94 AA.
AC   P58550; Q5JTT7;
DE   RecName: Full=Putative FXYD domain-containing ion transport regulator 8;
DE   Flags: Precursor;
GN   Name=FXYD6P3; Synonyms=FXYD8;
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
//
ID   FYB_HUMAN               Reviewed;         783 AA.
AC   O15117; A8K2Y8; B4DLN2; E9PBV9; O00359; Q9NZI9;
DE   RecName: Full=FYN-binding protein;
DE   AltName: Full=Adhesion and degranulation promoting adaptor protein;
DE            Short=ADAP;
DE   AltName: Full=FYB-120/130;
DE            Short=p120/p130;
DE   AltName: Full=FYN-T-binding protein;
DE   AltName: Full=SLAP-130;
DE   AltName: Full=SLP-76-associated phosphoprotein;
GN   Name=FYB; Synonyms=SLAP130;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   FYCO1_HUMAN             Reviewed;        1478 AA.
AC   Q9BQS8; B7ZKT7; Q3MJE6; Q86T41; Q86TB1; Q8TEF9; Q96IV5; Q9H8P9;
DE   RecName: Full=FYVE and coiled-coil domain-containing protein 1;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 7;
GN   Name=FYCO1; Synonyms=ZFYVE7;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0072383; P:plus-end-directed vesicle transport along microtubule; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   FYN_HUMAN               Reviewed;         537 AA.
AC   P06241; B5BU57; E1P557; H0UI48; Q16248; Q5R3A6; Q5R3A7; Q8N5D7;
DE   RecName: Full=Tyrosine-protein kinase Fyn;
DE            EC=2.7.10.2;
DE   AltName: Full=Proto-oncogene Syn;
DE   AltName: Full=Proto-oncogene c-Fyn;
DE   AltName: Full=Src-like kinase;
DE            Short=SLK;
DE   AltName: Full=p59-Fyn;
GN   Name=FYN;
DR   GuidetoPHARMACOLOGY; 2026; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0070851; F:growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; EXP:Reactome.
DR   GO; GO:0050798; P:activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:1900182; P:positive regulation of protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   FYV1_HUMAN              Reviewed;        2098 AA.
AC   Q9Y2I7; Q08AR7; Q08AR8; Q53ST3; Q53T36; Q8N5H0; Q8NB67;
DE   RecName: Full=1-phosphatidylinositol 3-phosphate 5-kinase;
DE            Short=Phosphatidylinositol 3-phosphate 5-kinase;
DE            EC=2.7.1.150;
DE   AltName: Full=FYVE finger-containing phosphoinositide kinase;
DE   AltName: Full=PIKfyve;
DE   AltName: Full=Phosphatidylinositol 3-phosphate 5-kinase type III;
DE            Short=PIPkin-III;
DE            Short=Type III PIP kinase;
GN   Name=PIKFYVE; Synonyms=KIAA0981, PIP5K3;
DR   GO; GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; TAS:HGNC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043813; F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0032288; P:myelin assembly; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; TAS:GOC.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; TAS:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0034504; P:protein localization to nucleus; IMP:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   FZD10_HUMAN             Reviewed;         581 AA.
AC   Q9ULW2;
DE   RecName: Full=Frizzled-10;
DE            Short=Fz-10;
DE            Short=hFz10;
DE   AltName: Full=FzE7;
DE   AltName: CD_antigen=CD350;
DE   Flags: Precursor;
GN   Name=FZD10;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0034259; P:negative regulation of Rho GTPase activity; IMP:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0038031; P:non-canonical Wnt signaling pathway via JNK cascade; IMP:BHF-UCL.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:BHF-UCL.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:BHF-UCL.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
//
ID   FZD1_HUMAN              Reviewed;         647 AA.
AC   Q9UP38; A4D1E8; O94815; Q549T8;
DE   RecName: Full=Frizzled-1;
DE            Short=Fz-1;
DE            Short=hFz1;
DE   AltName: Full=FzE1;
DE   Flags: Precursor;
GN   Name=FZD1;
DR   GuidetoPHARMACOLOGY; 229; -.
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0035425; P:autocrine signaling; IDA:BHF-UCL.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0044338; P:canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0044339; P:canonical Wnt signaling pathway involved in osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:BHF-UCL.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IBA:RefGenome.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0060022; P:hard palate development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IBA:RefGenome.
DR   GO; GO:0003149; P:membranous septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003150; P:muscular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IMP:BHF-UCL.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0007223; P:Wnt signaling pathway, calcium modulating pathway; IBA:RefGenome.
//
ID   FZD2_HUMAN              Reviewed;         565 AA.
AC   Q14332; Q0VG82;
DE   RecName: Full=Frizzled-2;
DE            Short=Fz-2;
DE            Short=hFz2;
DE   AltName: Full=FzE2;
DE   Flags: Precursor;
GN   Name=FZD2;
DR   GuidetoPHARMACOLOGY; 230; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IBA:RefGenome.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0060022; P:hard palate development; IEA:Ensembl.
DR   GO; GO:0060119; P:inner ear receptor cell development; IEA:Ensembl.
DR   GO; GO:0003149; P:membranous septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003150; P:muscular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0030825; P:positive regulation of cGMP metabolic process; IMP:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0007223; P:Wnt signaling pathway, calcium modulating pathway; IBA:RefGenome.
//
ID   FZD3_HUMAN              Reviewed;         666 AA.
AC   Q9NPG1; A8K615;
DE   RecName: Full=Frizzled-3;
DE            Short=Fz-3;
DE            Short=hFz3;
DE   Flags: Precursor;
GN   Name=FZD3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IC:BHF-UCL.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0033278; P:cell proliferation in midbrain; IBA:RefGenome.
DR   GO; GO:0071679; P:commissural neuron axon guidance; IBA:RefGenome.
DR   GO; GO:0001736; P:establishment of planar polarity; IBA:RefGenome.
DR   GO; GO:0021754; P:facial nucleus development; IBA:RefGenome.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IBA:RefGenome.
DR   GO; GO:0001843; P:neural tube closure; IBA:RefGenome.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
//
ID   FZD4_HUMAN              Reviewed;         537 AA.
AC   Q9ULV1; A8K9Q3; Q14C97; Q6S9E4;
DE   RecName: Full=Frizzled-4;
DE            Short=Fz-4;
DE            Short=hFz4;
DE   AltName: Full=FzE4;
DE   AltName: CD_antigen=CD344;
DE   Flags: Precursor;
GN   Name=FZD4;
DR   GO; GO:0019955; F:cytokine binding; IPI:BHF-UCL.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0061301; P:cerebellum vasculature morphogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0035426; P:extracellular matrix-cell signaling; IEA:Ensembl.
DR   GO; GO:0031987; P:locomotion involved in locomotory behavior; IEA:Ensembl.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IMP:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0042701; P:progesterone secretion; IBA:RefGenome.
DR   GO; GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IMP:BHF-UCL.
DR   GO; GO:0061304; P:retinal blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IBA:RefGenome.
DR   GO; GO:0001570; P:vasculogenesis; IBA:RefGenome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007223; P:Wnt signaling pathway, calcium modulating pathway; IDA:BHF-UCL.
//
ID   FZD5_HUMAN              Reviewed;         585 AA.
AC   Q13467; A8K2X1; B2RCZ1; Q53R22;
DE   RecName: Full=Frizzled-5;
DE            Short=Fz-5;
DE            Short=hFz5;
DE   AltName: Full=FzE5;
DE   Flags: Precursor;
GN   Name=FZD5; Synonyms=C2orf31;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IC:BHF-UCL.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IBA:RefGenome.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0071219; P:cellular response to molecule of bacterial origin; IDA:BHF-UCL.
DR   GO; GO:0000578; P:embryonic axis specification; IDA:BHF-UCL.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IBA:RefGenome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IMP:BHF-UCL.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0031077; P:post-embryonic camera-type eye development; IBA:RefGenome.
DR   GO; GO:0060061; P:Spemann organizer formation; IDA:BHF-UCL.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IBA:RefGenome.
DR   GO; GO:0044332; P:Wnt signaling pathway involved in dorsal/ventral axis specification; IDA:BHF-UCL.
//
ID   FZD6_HUMAN              Reviewed;         706 AA.
AC   O60353; B4DRN0; Q6N0A5; Q6P9C3; Q8WXR9;
DE   RecName: Full=Frizzled-6;
DE            Short=Fz-6;
DE            Short=hFz6;
DE   Flags: Precursor;
GN   Name=FZD6;
DR   GuidetoPHARMACOLOGY; 234; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0017147; F:Wnt-protein binding; ISS:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IBA:RefGenome.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0033278; P:cell proliferation in midbrain; IBA:RefGenome.
DR   GO; GO:0001736; P:establishment of planar polarity; IBA:RefGenome.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; IBA:RefGenome.
DR   GO; GO:0035567; P:non-canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   FZD7_HUMAN              Reviewed;         574 AA.
AC   O75084; O94816; Q53S59; Q96B74;
DE   RecName: Full=Frizzled-7;
DE            Short=Fz-7;
DE            Short=hFz7;
DE   AltName: Full=FzE3;
DE   Flags: Precursor;
GN   Name=FZD7;
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:BHF-UCL.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; IMP:BHF-UCL.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IMP:BHF-UCL.
DR   GO; GO:0042666; P:negative regulation of ectodermal cell fate specification; IMP:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0038031; P:non-canonical Wnt signaling pathway via JNK cascade; IMP:BHF-UCL.
DR   GO; GO:0060054; P:positive regulation of epithelial cell proliferation involved in wound healing; IMP:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IC:BHF-UCL.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0035412; P:regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0014834; P:satellite cell maintenance involved in skeletal muscle regeneration; IEA:Ensembl.
DR   GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IMP:BHF-UCL.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0007223; P:Wnt signaling pathway, calcium modulating pathway; IBA:RefGenome.
//
ID   FZD8_HUMAN              Reviewed;         694 AA.
AC   Q9H461;
DE   RecName: Full=Frizzled-8;
DE            Short=Fz-8;
DE            Short=hFz8;
DE   Flags: Precursor;
GN   Name=FZD8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; TAS:UniProtKB.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IBA:RefGenome.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
//
ID   FZD9_HUMAN              Reviewed;         591 AA.
AC   O00144;
DE   RecName: Full=Frizzled-9;
DE            Short=Fz-9;
DE            Short=hFz9;
DE   AltName: Full=FzE6;
DE   AltName: CD_antigen=CD349;
DE   Flags: Precursor;
GN   Name=FZD9; Synonyms=FZD3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007405; P:neuroblast proliferation; IBA:RefGenome.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
//
ID   FZR_HUMAN               Reviewed;         496 AA.
AC   Q9UM11; O75869; Q86U66; Q96NW8; Q9UI96; Q9ULH8; Q9UM10; Q9UNQ1;
AC   Q9Y2T8;
DE   RecName: Full=Fizzy-related protein homolog;
DE            Short=Fzr;
DE   AltName: Full=CDC20-like protein 1;
DE   AltName: Full=Cdh1/Hct1 homolog;
DE            Short=hCDH1;
GN   Name=FZR1; Synonyms=CDH1, FYR, FZR, KIAA1242;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090344; P:negative regulation of cell aging; IEA:Ensembl.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IGI:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; TAS:UniProtKB.
DR   GO; GO:0040020; P:regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   G0S2_HUMAN              Reviewed;         103 AA.
AC   P27469; Q6FGC8;
DE   RecName: Full=G0/G1 switch protein 2;
DE   AltName: Full=G0/G1 switch regulatory protein 2;
DE   AltName: Full=Putative lymphocyte G0/G1 switch gene;
GN   Name=G0S2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   G137A_HUMAN             Reviewed;         417 AA.
AC   Q96N19; B4DTG7; B7Z7M1; Q4G0Y9; Q8N4K6;
DE   RecName: Full=Integral membrane protein GPR137;
DE   AltName: Full=Transmembrane 7 superfamily member 1-like 1 protein;
GN   Name=GPR137; Synonyms=C11orf4, GPR137A, TM7SF1L1;
//
ID   G137B_HUMAN             Reviewed;         399 AA.
AC   O60478; Q53EK7; Q5TAE6; Q6FHI3;
DE   RecName: Full=Integral membrane protein GPR137B;
DE   AltName: Full=Transmembrane 7 superfamily member 1 protein;
GN   Name=GPR137B; Synonyms=TM7SF1;
//
ID   G137C_HUMAN             Reviewed;         429 AA.
AC   Q8N3F9; Q86SM2;
DE   RecName: Full=Integral membrane protein GPR137C;
DE   AltName: Full=Transmembrane 7 superfamily member 1-like 2 protein;
GN   Name=GPR137C; Synonyms=TM7SF1L2;
//
ID   G2E3_HUMAN              Reviewed;         706 AA.
AC   Q7L622; Q9BVR2; Q9H9E9; Q9NXC0; Q9P2L3;
DE   RecName: Full=G2/M phase-specific E3 ubiquitin-protein ligase;
DE            EC=6.3.2.-;
GN   Name=G2E3; Synonyms=KIAA1333;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
//
ID   G32P1_HUMAN             Reviewed;         272 AA.
AC   Q8NGA4; Q8TDT1;
DE   RecName: Full=Putative G-protein coupled receptor GPR32P1;
DE   AltName: Full=G-protein coupled 32 pseudogene;
DE   AltName: Full=G-protein coupled 32 pseudogene 1;
DE   AltName: Full=G-protein coupled receptor GPCR39;
DE            Short=hGPCR39;
GN   Name=GPR32P1;
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
//
ID   G3BP1_HUMAN             Reviewed;         466 AA.
AC   Q13283;
DE   RecName: Full=Ras GTPase-activating protein-binding protein 1;
DE            Short=G3BP-1;
DE            EC=3.6.4.12;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent DNA helicase VIII;
DE            Short=hDH VIII;
DE   AltName: Full=GAP SH3 domain-binding protein 1;
GN   Name=G3BP1; Synonyms=G3BP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   G3BP2_HUMAN             Reviewed;         482 AA.
AC   Q9UN86; A8K6X1; O60606; O75149; Q9UPA1;
DE   RecName: Full=Ras GTPase-activating protein-binding protein 2;
DE            Short=G3BP-2;
DE   AltName: Full=GAP SH3 domain-binding protein 2;
GN   Name=G3BP2; Synonyms=KIAA0660;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0007253; P:cytoplasmic sequestering of NF-kappaB; NAS:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
//
ID   G3PT_HUMAN              Reviewed;         408 AA.
AC   O14556; B2RC82; O60823; Q6JTT9; Q9HCU6;
DE   RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase, testis-specific;
DE            EC=1.2.1.12;
DE   AltName: Full=Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2;
DE            Short=GAPDH-2;
DE   AltName: Full=Spermatogenic glyceraldehyde-3-phosphate dehydrogenase;
GN   Name=GAPDHS; Synonyms=GAPD2, GAPDH2, GAPDS; ORFNames=HSD-35, HSD35;
DR   GO; GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; TAS:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030317; P:sperm motility; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   G3P_HUMAN               Reviewed;         335 AA.
AC   P04406; E7EUT4; P00354; Q53X65;
DE   RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase;
DE            Short=GAPDH;
DE            EC=1.2.1.12;
DE   AltName: Full=Peptidyl-cysteine S-nitrosylase GAPDH;
DE            EC=2.6.99.-;
GN   Name=GAPDH; Synonyms=GAPD; ORFNames=CDABP0047, OK/SW-cl.12;
DR   GO; GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; ISS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0035605; F:peptidyl-cysteine S-nitrosylase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0035606; P:peptidyl-cysteine S-trans-nitrosylation; ISS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   G3ST1_HUMAN             Reviewed;         423 AA.
AC   Q99999; Q96C63;
DE   RecName: Full=Galactosylceramide sulfotransferase;
DE            Short=GalCer sulfotransferase;
DE            EC=2.8.2.11;
DE   AltName: Full=3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase;
DE   AltName: Full=3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase;
DE   AltName: Full=Cerebroside sulfotransferase;
GN   Name=GAL3ST1; Synonyms=CST;
DR   GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0006682; P:galactosylceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0006487; P:protein N-linked glycosylation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   G3ST2_HUMAN             Reviewed;         398 AA.
AC   Q9H3Q3; Q17RK0; Q57Z52;
DE   RecName: Full=Galactose-3-O-sulfotransferase 2;
DE            Short=Gal3ST-2;
DE            EC=2.8.2.-;
DE   AltName: Full=Beta-galactose-3-O-sulfotransferase 2;
DE   AltName: Full=Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2;
DE   AltName: Full=Glycoprotein beta-Gal 3'-sulfotransferase 2;
GN   Name=GAL3ST2; Synonyms=GP3ST;
DR   GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0008146; F:sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
//
ID   G3ST3_HUMAN             Reviewed;         431 AA.
AC   Q96A11; Q14D05;
DE   RecName: Full=Galactose-3-O-sulfotransferase 3;
DE            Short=Gal3ST-3;
DE            EC=2.8.2.-;
DE   AltName: Full=Beta-galactose-3-O-sulfotransferase 3;
DE            Short=Gal3ST3;
DE   AltName: Full=Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3;
GN   Name=GAL3ST3;
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; NAS:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0050694; F:galactose 3-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0050698; F:proteoglycan sulfotransferase activity; NAS:UniProtKB.
DR   GO; GO:0005996; P:monosaccharide metabolic process; NAS:UniProtKB.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; NAS:UniProtKB.
DR   GO; GO:0030309; P:poly-N-acetyllactosamine metabolic process; NAS:UniProtKB.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006790; P:sulfur compound metabolic process; NAS:UniProtKB.
//
ID   G3ST4_HUMAN             Reviewed;         486 AA.
AC   Q96RP7; A4D2A8; D6W5U5; Q8N3P7; Q8WZ17; Q96E33; Q9HA78;
DE   RecName: Full=Galactose-3-O-sulfotransferase 4;
DE            Short=Gal3ST-4;
DE            EC=2.8.2.-;
DE   AltName: Full=Beta-galactose-3-O-sulfotransferase 4;
DE   AltName: Full=Gal-beta-1,3-GalNAc 3'-sulfotransferase;
GN   Name=GAL3ST4; ORFNames=PP6968;
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; NAS:UniProtKB.
DR   GO; GO:0050694; F:galactose 3-O-sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0050698; F:proteoglycan sulfotransferase activity; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0009100; P:glycoprotein metabolic process; NAS:UniProtKB.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; NAS:UniProtKB.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006790; P:sulfur compound metabolic process; NAS:UniProtKB.
//
ID   G45IP_HUMAN             Reviewed;         222 AA.
AC   Q8TAE8; Q8IVM3; Q8TE51; Q969P9; Q9BSM6;
DE   RecName: Full=Growth arrest and DNA damage-inducible proteins-interacting protein 1;
DE   AltName: Full=39S ribosomal protein L59, mitochondrial;
DE            Short=MRP-L59;
DE   AltName: Full=CKII beta-associating protein;
DE   AltName: Full=CR6-interacting factor 1;
DE            Short=CRIF1;
DE   AltName: Full=Papillomavirus L2-interacting nuclear protein 1;
DE            Short=PLINP;
DE            Short=PLINP-1;
DE   AltName: Full=p53-responsive gene 6 protein;
GN   Name=GADD45GIP1; Synonyms=MRPL59, PLINP1, PRG6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   G6B_HUMAN               Reviewed;         241 AA.
AC   O95866; A2BEZ1; A2BEZ2; A2BEZ3; A2BEZ4; A2BEZ5; B0UXC4; B0UXC7;
AC   B0UXC8; B0V024; B0V026; Q14CK2; Q96A86; Q96A87; Q96A88; Q96A89;
AC   Q96A90; Q96A91;
DE   RecName: Full=Protein G6b;
DE   Flags: Precursor;
GN   Name=G6B; Synonyms=C6orf25;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
//
ID   G6PC2_HUMAN             Reviewed;         355 AA.
AC   Q9NQR9; E9PAX2; Q6AHZ0;
DE   RecName: Full=Glucose-6-phosphatase 2;
DE            Short=G-6-Pase 2;
DE            Short=G6Pase 2;
DE            EC=3.1.3.9;
DE   AltName: Full=Islet-specific glucose-6-phosphatase catalytic subunit-related protein;
GN   Name=G6PC2; Synonyms=IGRP;
DR   GO; GO:0004346; F:glucose-6-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   G6PC3_HUMAN             Reviewed;         346 AA.
AC   Q9BUM1; Q8WU15;
DE   RecName: Full=Glucose-6-phosphatase 3;
DE            Short=G-6-Pase 3;
DE            Short=G6Pase 3;
DE            EC=3.1.3.9;
DE   AltName: Full=Glucose-6-phosphatase beta;
DE            Short=G6Pase-beta;
DE   AltName: Full=Ubiquitous glucose-6-phosphatase catalytic subunit-related protein;
GN   Name=G6PC3; Synonyms=UGRP;
DR   GO; GO:0004346; F:glucose-6-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0015760; P:glucose-6-phosphate transport; IEA:Ensembl.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   G6PC_HUMAN              Reviewed;         357 AA.
AC   P35575; A1L4C0; B4E1C3; K7EL82;
DE   RecName: Full=Glucose-6-phosphatase;
DE            Short=G-6-Pase;
DE            Short=G6Pase;
DE            EC=3.1.3.9;
DE   AltName: Full=Glucose-6-phosphatase alpha;
DE            Short=G6Pase-alpha;
GN   Name=G6PC; Synonyms=G6PT;
DR   GO; GO:0004346; F:glucose-6-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042301; F:phosphate ion binding; IMP:UniProtKB.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0006094; P:gluconeogenesis; IMP:UniProtKB.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0015760; P:glucose-6-phosphate transport; IEA:Ensembl.
DR   GO; GO:0005980; P:glycogen catabolic process; IEA:Ensembl.
DR   GO; GO:0005977; P:glycogen metabolic process; TAS:ProtInc.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
DR   GO; GO:0046415; P:urate metabolic process; IEA:Ensembl.
//
ID   G6PD_HUMAN              Reviewed;         515 AA.
AC   P11413; D3DWX9; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2;
DE   RecName: Full=Glucose-6-phosphate 1-dehydrogenase;
DE            Short=G6PD;
DE            EC=1.1.1.49;
GN   Name=G6PD;
DR   GO; GO:0005536; F:glucose binding; IDA:BHF-UCL.
DR   GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0001816; P:cytokine production; IMP:BHF-UCL.
DR   GO; GO:0043249; P:erythrocyte maturation; IMP:BHF-UCL.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:BHF-UCL.
DR   GO; GO:0006739; P:NADP metabolic process; IDA:UniProtKB.
DR   GO; GO:0006740; P:NADPH regeneration; IMP:BHF-UCL.
DR   GO; GO:0010734; P:negative regulation of protein glutathionylation; IMP:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IMP:BHF-UCL.
DR   GO; GO:0019322; P:pentose biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IDA:BHF-UCL.
DR   GO; GO:0009051; P:pentose-phosphate shunt, oxidative branch; IMP:BHF-UCL.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0046390; P:ribose phosphate biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   G6PE_HUMAN              Reviewed;         791 AA.
AC   O95479; Q4TT33; Q66I35; Q68DT3;
DE   RecName: Full=GDH/6PGL endoplasmic bifunctional protein;
DE   Includes:
DE     RecName: Full=Glucose 1-dehydrogenase;
DE              EC=1.1.1.47;
DE     AltName: Full=Hexose-6-phosphate dehydrogenase;
DE   Includes:
DE     RecName: Full=6-phosphogluconolactonase;
DE              Short=6PGL;
DE              EC=3.1.1.31;
DE   Flags: Precursor;
GN   Name=H6PD; Synonyms=GDH;
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0047936; F:glucose 1-dehydrogenase [NAD(P)] activity; IEA:UniProtKB-EC.
DR   GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0050661; F:NADP binding; IEA:Ensembl.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:Ensembl.
DR   GO; GO:0097305; P:response to alcohol; IEA:Ensembl.
//
ID   G6PI_HUMAN              Reviewed;         558 AA.
AC   P06744; B4DG39; Q9BRD3; Q9BSK5; Q9UHE6;
DE   RecName: Full=Glucose-6-phosphate isomerase;
DE            Short=GPI;
DE            EC=5.3.1.9;
DE   AltName: Full=Autocrine motility factor;
DE            Short=AMF;
DE   AltName: Full=Neuroleukin;
DE            Short=NLK;
DE   AltName: Full=Phosphoglucose isomerase;
DE            Short=PGI;
DE   AltName: Full=Phosphohexose isomerase;
DE            Short=PHI;
DE   AltName: Full=Sperm antigen 36;
DE            Short=SA-36;
GN   Name=GPI;
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; TAS:Reactome.
DR   GO; GO:0016866; F:intramolecular transferase activity; IEA:Ensembl.
DR   GO; GO:0048029; F:monosaccharide binding; IEA:Ensembl.
DR   GO; GO:0046185; P:aldehyde catabolic process; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0007599; P:hemostasis; TAS:ProtInc.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0019242; P:methylglyoxal biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   G6PT1_HUMAN             Reviewed;         429 AA.
AC   O43826; O96016; Q5J7V4; Q9UI19; Q9UNS4;
DE   RecName: Full=Glucose-6-phosphate translocase;
DE   AltName: Full=Glucose-5-phosphate transporter;
DE   AltName: Full=Solute carrier family 37 member 4;
DE   AltName: Full=Transformation-related gene 19 protein;
DE            Short=TRG-19;
GN   Name=SLC37A4; Synonyms=G6PT, G6PT1; ORFNames=PRO0685, TRG19;
DR   GO; GO:0015152; F:glucose-6-phosphate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; IDA:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; NAS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0015760; P:glucose-6-phosphate transport; IDA:UniProtKB.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   G8_HUMAN                Reviewed;          75 AA.
AC   Q9UBA6; Q9BW21; Q9UBA7; Q9UBA8;
DE   RecName: Full=Protein G8;
GN   Name=C6orf48; Synonyms=G8;
//
ID   GA2L1_HUMAN             Reviewed;         681 AA.
AC   Q99501; Q53EN7; Q92640; Q9BUY9;
DE   RecName: Full=GAS2-like protein 1;
DE   AltName: Full=GAS2-related protein on chromosome 22;
DE   AltName: Full=Growth arrest-specific protein 2-like 1;
GN   Name=GAS2L1; Synonyms=GAR22;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:UniProtKB.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
//
ID   GA2L2_HUMAN             Reviewed;         880 AA.
AC   Q8NHY3; Q8NHY4;
DE   RecName: Full=GAS2-like protein 2;
DE   AltName: Full=GAS2-related protein on chromosome 17;
DE   AltName: Full=Growth arrest-specific protein 2-like 2;
GN   Name=GAS2L2; Synonyms=GAR17;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
DR   GO; GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.
//
ID   GA2L3_HUMAN             Reviewed;         694 AA.
AC   Q86XJ1; B2RCN2;
DE   RecName: Full=GAS2-like protein 3;
DE   AltName: Full=Growth arrest-specific protein 2-like 3;
GN   Name=GAS2L3;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IDA:UniProtKB.
//
ID   GA45A_HUMAN             Reviewed;         165 AA.
AC   P24522; Q5TCA7; Q5TCA8;
DE   RecName: Full=Growth arrest and DNA damage-inducible protein GADD45 alpha;
DE   AltName: Full=DNA damage-inducible transcript 1 protein;
DE            Short=DDIT-1;
GN   Name=GADD45A; Synonyms=DDIT1, GADD45;
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0007098; P:centrosome cycle; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.
//
ID   GA45B_HUMAN             Reviewed;         160 AA.
AC   O75293; A8KAM2; O75960; Q17R46;
DE   RecName: Full=Growth arrest and DNA damage-inducible protein GADD45 beta;
DE   AltName: Full=Myeloid differentiation primary response protein MyD118;
DE   AltName: Full=Negative growth regulatory protein MyD118;
GN   Name=GADD45B; Synonyms=MYD118;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IEA:InterPro.
//
ID   GA45G_HUMAN             Reviewed;         159 AA.
AC   O95257; Q9C076;
DE   RecName: Full=Growth arrest and DNA damage-inducible protein GADD45 gamma;
DE   AltName: Full=Cytokine-responsive protein CR6;
DE   AltName: Full=DNA damage-inducible transcript 2 protein;
DE            Short=DDIT-2;
GN   Name=GADD45G; Synonyms=CR6, DDIT2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IEA:InterPro.
//
ID   GAB1_HUMAN              Reviewed;         694 AA.
AC   Q13480; A8K152; Q4W5G2; Q6P1W2;
DE   RecName: Full=GRB2-associated-binding protein 1;
DE   AltName: Full=GRB2-associated binder 1;
DE   AltName: Full=Growth factor receptor bound protein 2-associated protein 1;
GN   Name=GAB1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
//
ID   GAB2_HUMAN              Reviewed;         676 AA.
AC   Q9UQC2; A2RRM2; A6NEW9; A7MD36; O60317;
DE   RecName: Full=GRB2-associated-binding protein 2;
DE   AltName: Full=GRB2-associated binder 2;
DE   AltName: Full=Growth factor receptor bound protein 2-associated protein 2;
DE   AltName: Full=pp100;
GN   Name=GAB2; Synonyms=KIAA0571;
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030316; P:osteoclast differentiation; IMP:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:GOC.
//
ID   GAB3_HUMAN              Reviewed;         586 AA.
AC   Q8WWW8; E9PB44;
DE   RecName: Full=GRB2-associated-binding protein 3;
DE   AltName: Full=GRB2-associated binder 3;
DE   AltName: Full=Growth factor receptor bound protein 2-associated protein 3;
GN   Name=GAB3;
DR   GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
//
ID   GAB4_HUMAN              Reviewed;         574 AA.
AC   Q2WGN9;
DE   RecName: Full=GRB2-associated-binding protein 4;
DE   AltName: Full=GRB2-associated binder 2-like;
DE            Short=GAB2-like;
DE   AltName: Full=GRB2-associated binder 4;
DE   AltName: Full=GRB2-associated-binding protein 2-like;
DE   AltName: Full=Growth factor receptor bound protein 2-associated protein 4;
GN   Name=GAB4;
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
//
ID   GABP1_HUMAN             Reviewed;         395 AA.
AC   Q06547; A8IE52; Q06545; Q12940; Q12941; Q12942; Q8IYD0;
DE   RecName: Full=GA-binding protein subunit beta-1;
DE            Short=GABP subunit beta-1;
DE            Short=GABPB-1;
DE   AltName: Full=GABP subunit beta-2;
DE            Short=GABPB-2;
DE   AltName: Full=Nuclear respiratory factor 2;
DE   AltName: Full=Transcription factor E4TF1-47;
DE   AltName: Full=Transcription factor E4TF1-53;
GN   Name=GABPB1; Synonyms=E4TF1B, GABPB, GABPB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GABP2_HUMAN             Reviewed;         448 AA.
AC   Q8TAK5; B1AVJ8; D3DV14; Q8NAR5;
DE   RecName: Full=GA-binding protein subunit beta-2;
DE            Short=GABP subunit beta-2;
DE            Short=GABPB-2;
GN   Name=GABPB2;
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GABPA_HUMAN             Reviewed;         454 AA.
AC   Q06546; Q12939;
DE   RecName: Full=GA-binding protein alpha chain;
DE            Short=GABP subunit alpha;
DE   AltName: Full=Nuclear respiratory factor 2 subunit alpha;
DE   AltName: Full=Transcription factor E4TF1-60;
GN   Name=GABPA; Synonyms=E4TF1A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045653; P:negative regulation of megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   GABR1_HUMAN             Reviewed;         961 AA.
AC   Q9UBS5; B0UXY7; O95375; O95468; O95975; O96022; Q5STL4; Q5SUJ8;
AC   Q5SUL3; Q71SG6; Q86W60; Q9UQQ0;
DE   RecName: Full=Gamma-aminobutyric acid type B receptor subunit 1;
DE            Short=GABA-B receptor 1;
DE            Short=GABA-B-R1;
DE            Short=GABA-BR1;
DE            Short=GABABR1;
DE            Short=Gb1;
DE   Flags: Precursor;
GN   Name=GABBR1; Synonyms=GPRC3A;
DR   GuidetoPHARMACOLOGY; 240; -.
DR   GO; GO:0004965; F:G-protein coupled GABA receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GABR2_HUMAN             Reviewed;         941 AA.
AC   O75899; O75974; O75975; Q5VXZ2; Q8WX04; Q9P1R2; Q9UNR1; Q9UNS9;
DE   RecName: Full=Gamma-aminobutyric acid type B receptor subunit 2;
DE            Short=GABA-B receptor 2;
DE            Short=GABA-B-R2;
DE            Short=GABA-BR2;
DE            Short=GABABR2;
DE            Short=Gb2;
DE   AltName: Full=G-protein coupled receptor 51;
DE   AltName: Full=HG20;
DE   Flags: Precursor;
GN   Name=GABBR2; Synonyms=GPR51, GPRC3B;
DR   GO; GO:0004965; F:G-protein coupled GABA receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GABT_HUMAN              Reviewed;         500 AA.
AC   P80404; A8K386; Q16260; Q8N5W2; Q96BG2; Q99800;
DE   RecName: Full=4-aminobutyrate aminotransferase, mitochondrial;
DE            EC=2.6.1.19;
DE   AltName: Full=(S)-3-amino-2-methylpropionate transaminase;
DE            EC=2.6.1.22;
DE   AltName: Full=GABA aminotransferase;
DE            Short=GABA-AT;
DE   AltName: Full=Gamma-amino-N-butyrate transaminase;
DE            Short=GABA transaminase;
DE            Short=GABA-T;
DE   AltName: Full=L-AIBAT;
DE   Flags: Precursor;
GN   Name=ABAT; Synonyms=GABAT;
DR   GuidetoPHARMACOLOGY; 2464; -.
DR   GO; GO:0047298; F:(S)-3-amino-2-methylpropionate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003867; F:4-aminobutyrate transaminase activity; TAS:Reactome.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0032145; F:succinate-semialdehyde dehydrogenase binding; ISS:UniProtKB.
DR   GO; GO:0048148; P:behavioral response to cocaine; ISS:UniProtKB.
DR   GO; GO:0007620; P:copulation; IEA:Ensembl.
DR   GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; NAS:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GADL1_HUMAN             Reviewed;         521 AA.
AC   Q6ZQY3;
DE   RecName: Full=Glutamate decarboxylase-like protein 1;
DE   AltName: Full=Aspartate 1-decarboxylase;
DE            Short=ADC;
DE            Short=HuADC;
DE            EC=4.1.1.11;
DE   AltName: Full=Cysteine sulfinic acid decarboxylase;
DE            Short=CSADC;
DE            Short=HuCSADC;
GN   Name=GADL1;
DR   GO; GO:0004068; F:aspartate 1-decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
//
ID   GAFA1_HUMAN             Reviewed;          74 AA.
AC   Q96PS6;
DE   RecName: Full=Putative uncharacterized protein GAFA-1;
DE   AltName: Full=Gene associated with FGF-2 activity protein 1;
GN   Name=GAFA1;
//
ID   GAG10_HUMAN             Reviewed;         116 AA.
AC   A6NGK3;
DE   RecName: Full=G antigen 10;
DE            Short=GAGE-10;
GN   Name=GAGE10;
//
ID   GAG13_HUMAN             Reviewed;         117 AA.
AC   Q4V321;
DE   RecName: Full=G antigen 13;
DE            Short=GAGE-13;
DE   AltName: Full=G antigen 12A;
DE            Short=GAGE-12A;
GN   Name=GAGE13; Synonyms=GAGE12A;
//
ID   GAG2B_HUMAN             Reviewed;         116 AA.
AC   Q13066; C9K0W9; Q4V322;
DE   RecName: Full=G antigen 2B/2C;
DE            Short=GAGE-2B;
DE            Short=GAGE-2C;
DE   AltName: Full=Cancer/testis antigen 4.2;
DE            Short=CT4.2;
DE   AltName: Full=G antigen 2C;
GN   Name=GAGE2B; Synonyms=GAGE2;
GN   and
GN   Name=GAGE2C;
//
ID   GAG2A_HUMAN             Reviewed;         116 AA.
AC   Q6NT46;
DE   RecName: Full=G antigen 2A;
DE            Short=GAGE-2A;
GN   Name=GAGE2A; Synonyms=GAGE2;
//
ID   GAG2E_HUMAN             Reviewed;         116 AA.
AC   Q4V326; A6NFB1;
DE   RecName: Full=G antigen 2E;
DE            Short=GAGE-2E;
GN   Name=GAGE2E;
//
ID   GAGE1_HUMAN             Reviewed;         139 AA.
AC   Q13065;
DE   RecName: Full=G antigen 1;
DE            Short=GAGE-1;
DE   AltName: Full=Antigen MZ2-F;
DE   AltName: Full=Cancer/testis antigen 4.1;
DE            Short=CT4.1;
GN   Name=GAGE1;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   GAGE3_HUMAN             Reviewed;         118 AA.
AC   Q13067;
DE   RecName: Full=G antigen 3;
DE            Short=GAGE-3;
DE   AltName: Full=Cancer/testis antigen 4.3;
DE            Short=CT4.3;
GN   Name=GAGE3;
//
ID   GAGE4_HUMAN             Reviewed;         117 AA.
AC   Q13068; A8MU85; Q6NT33;
DE   RecName: Full=G antigen 4;
DE            Short=GAGE-4;
DE   AltName: Full=Cancer/testis antigen 4.4;
DE            Short=CT4.4;
GN   Name=GAGE4;
//
ID   GAGE7_HUMAN             Reviewed;         117 AA.
AC   O76087; B7ZM13; Q4V324;
DE   RecName: Full=G antigen 7;
DE            Short=GAGE-7;
DE   AltName: Full=AL4;
DE   AltName: Full=Cancer/testis antigen 4.7;
DE            Short=CT4.7;
DE   AltName: Full=GAGE-12I;
DE   AltName: Full=GAGE-7B;
DE   AltName: Full=GAGE-8;
GN   Name=GAGE7; Synonyms=GAGE12I, GAGE7B;
//
ID   GAGE6_HUMAN             Reviewed;         117 AA.
AC   Q13070;
DE   RecName: Full=G antigen 6;
DE            Short=GAGE-6;
DE   AltName: Full=Cancer/testis antigen 4.6;
DE            Short=CT4.6;
GN   Name=GAGE6;
//
ID   GAGE5_HUMAN             Reviewed;         117 AA.
AC   Q13069; Q6FG72;
DE   RecName: Full=G antigen 5;
DE            Short=GAGE-5;
DE   AltName: Full=Cancer/testis antigen 4.5;
DE            Short=CT4.5;
GN   Name=GAGE5;
//
ID   GAH6_HUMAN              Reviewed;         274 AA.
AC   Q8N8A4;
DE   RecName: Full=HERV-H_22q11.2 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAJU_HUMAN              Reviewed;          10 AA.
AC   P01358;
DE   RecName: Full=Gastric juice peptide 1;
DE   Contains:
DE     RecName: Full=Gastric juice peptide 2;
DR   GO; GO:0007586; P:digestion; NAS:UniProtKB.
//
ID   GAK10_HUMAN             Reviewed;         666 AA.
AC   P87889; P10263; P10264; Q69385; Q9UKH6;
DE   RecName: Full=HERV-K_5q33.3 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K10 Gag protein;
DE   AltName: Full=HERV-K107 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK12_HUMAN             Reviewed;         666 AA.
AC   P63130; Q9UKI0;
DE   RecName: Full=HERV-K_1q22 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K(III) Gag protein;
DE   AltName: Full=HERV-K102 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK11_HUMAN             Reviewed;         666 AA.
AC   P63145; Q9UKI1;
DE   RecName: Full=HERV-K_22q11.21 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K101 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK1_HUMAN              Reviewed;         666 AA.
AC   P62683;
DE   RecName: Full=HERV-K_12q14.1 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK2_HUMAN              Reviewed;         666 AA.
AC   Q7LDI9; Q9UKH5; Q9Y6I1; Q9YNA6; Q9YNB0;
DE   RecName: Full=HERV-K_7p22.1 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K(C7) Gag protein;
DE   AltName: Full=HERV-K(HML-2.HOM) Gag protein;
DE   AltName: Full=HERV-K108 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
GN   Name=ERVK6;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK3_HUMAN              Reviewed;         666 AA.
AC   Q9YNA8;
DE   RecName: Full=HERV-K_19q12 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K(C19) Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK5_HUMAN              Reviewed;         666 AA.
AC   P62684;
DE   RecName: Full=HERV-K_19p13.11 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K113 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK6_HUMAN              Reviewed;         647 AA.
AC   P62685;
DE   RecName: Full=HERV-K_8p23.1 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K115 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK4_HUMAN              Reviewed;         666 AA.
AC   P63126; Q9UKH4;
DE   RecName: Full=HERV-K_6q14.1 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K(C6) Gag protein;
DE   AltName: Full=HERV-K109 Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK8_HUMAN              Reviewed;         667 AA.
AC   Q9HDB9;
DE   RecName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein;
DE            Short=Gag polyprotein;
DE   AltName: Full=HERV-K(II) Gag protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
GN   Name=ERVK-5; Synonyms=ERVK5;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   GAK_HUMAN               Reviewed;        1311 AA.
AC   O14976; Q5U4P5; Q9BVY6;
DE   RecName: Full=Cyclin-G-associated kinase;
DE            EC=2.7.11.1;
GN   Name=GAK;
DR   GuidetoPHARMACOLOGY; 2027; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   GALA_HUMAN              Reviewed;         123 AA.
AC   P22466; Q14413;
DE   RecName: Full=Galanin peptides;
DE   Contains:
DE     RecName: Full=Galanin;
DE   Contains:
DE     RecName: Full=Galanin message-associated peptide;
DE              Short=GMAP;
DE   Flags: Precursor;
GN   Name=GAL; Synonyms=GAL1, GALN, GLNN;
DR   GO; GO:0005184; F:neuropeptide hormone activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IDA:UniProt.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; NAS:UniProtKB.
DR   GO; GO:0050672; P:negative regulation of lymphocyte proliferation; IEA:Ensembl.
DR   GO; GO:1902891; P:negative regulation of root hair elongation; IDA:UniProt.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051795; P:positive regulation of catagen; IDA:UniProt.
DR   GO; GO:0051464; P:positive regulation of cortisol secretion; IDA:UniProt.
DR   GO; GO:1902608; P:positive regulation of large conductance calcium-activated potassium channel activity; IDA:UniProt.
DR   GO; GO:0010737; P:protein kinase A signaling; IDA:UniProt.
DR   GO; GO:0031943; P:regulation of glucocorticoid metabolic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   GALC_HUMAN              Reviewed;         685 AA.
AC   P54803; B4DKE8; B4DYN1; B4DZJ8; B7Z7Z2; J3KN25; J3KPP8; Q8J030;
DE   RecName: Full=Galactocerebrosidase;
DE            Short=GALCERase;
DE            EC=3.2.1.46;
DE   AltName: Full=Galactocerebroside beta-galactosidase;
DE   AltName: Full=Galactosylceramidase;
DE   AltName: Full=Galactosylceramide beta-galactosidase;
DE   Flags: Precursor;
GN   Name=GALC;
DR   GO; GO:0004336; F:galactosylceramidase activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006683; P:galactosylceramide catabolic process; ISS:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   GALE_HUMAN              Reviewed;         348 AA.
AC   Q14376; Q86W41; Q9BVE3; Q9UJB4;
DE   RecName: Full=UDP-glucose 4-epimerase;
DE            EC=5.1.3.2;
DE   AltName: Full=Galactowaldenase;
DE   AltName: Full=UDP-galactose 4-epimerase;
GN   Name=GALE;
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; IEA:InterPro.
DR   GO; GO:0019388; P:galactose catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GALK1_HUMAN             Reviewed;         392 AA.
AC   P51570; B2RC07;
DE   RecName: Full=Galactokinase;
DE            EC=2.7.1.6;
DE   AltName: Full=Galactose kinase;
GN   Name=GALK1; Synonyms=GALK;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004335; F:galactokinase activity; IDA:UniProtKB.
DR   GO; GO:0005534; F:galactose binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019402; P:galactitol metabolic process; IEA:Ensembl.
DR   GO; GO:0019388; P:galactose catabolic process; TAS:Reactome.
DR   GO; GO:0006012; P:galactose metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GALK2_HUMAN             Reviewed;         458 AA.
AC   Q01415; Q7Z4Q4;
DE   RecName: Full=N-acetylgalactosamine kinase;
DE            EC=2.7.1.157;
DE   AltName: Full=GalNAc kinase;
DE   AltName: Full=Galactokinase 2;
GN   Name=GALK2; Synonyms=GK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004335; F:galactokinase activity; IDA:UniProtKB.
DR   GO; GO:0033858; F:N-acetylgalactosamine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
//
ID   GALM_HUMAN              Reviewed;         342 AA.
AC   Q96C23; Q53RY1; Q8NIA2;
DE   RecName: Full=Aldose 1-epimerase;
DE            EC=5.1.3.3;
DE   AltName: Full=Galactose mutarotase;
GN   Name=GALM; ORFNames=BLOCK25;
DR   GO; GO:0004034; F:aldose 1-epimerase activity; IDA:UniProt.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006012; P:galactose metabolic process; IDA:UniProt.
DR   GO; GO:0006006; P:glucose metabolic process; IDA:UniProt.
//
ID   GALNS_HUMAN             Reviewed;         522 AA.
AC   P34059; Q86VK3;
DE   RecName: Full=N-acetylgalactosamine-6-sulfatase;
DE            EC=3.1.6.4;
DE   AltName: Full=Chondroitinsulfatase;
DE            Short=Chondroitinase;
DE   AltName: Full=Galactose-6-sulfate sulfatase;
DE            Short=GalN6S;
DE   AltName: Full=N-acetylgalactosamine-6-sulfate sulfatase;
DE            Short=GalNAc6S sulfatase;
DE   Flags: Precursor;
GN   Name=GALNS;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003943; F:N-acetylgalactosamine-4-sulfatase activity; TAS:ProtInc.
DR   GO; GO:0043890; F:N-acetylgalactosamine-6-sulfatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IDA:MGI.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GALP_HUMAN              Reviewed;         116 AA.
AC   Q9UBC7; A1KXL3;
DE   RecName: Full=Galanin-like peptide;
DE   Flags: Precursor;
GN   Name=GALP;
DR   GO; GO:0042595; P:behavioral response to starvation; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0032098; P:regulation of appetite; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   GALR1_HUMAN             Reviewed;         349 AA.
AC   P47211; Q4VBL7;
DE   RecName: Full=Galanin receptor type 1;
DE            Short=GAL1-R;
DE            Short=GALR-1;
GN   Name=GALR1; Synonyms=GALNR, GALNR1;
DR   GuidetoPHARMACOLOGY; 243; -.
DR   GO; GO:0004966; F:galanin receptor activity; TAS:ProtInc.
DR   GO; GO:0042923; F:neuropeptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0051464; P:positive regulation of cortisol secretion; IMP:UniProt.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:InterPro.
//
ID   GALR2_HUMAN             Reviewed;         387 AA.
AC   O43603; A5JUU4; Q32MN8;
DE   RecName: Full=Galanin receptor type 2;
DE            Short=GAL2-R;
DE            Short=GALR-2;
GN   Name=GALR2; Synonyms=GALNR2;
DR   GuidetoPHARMACOLOGY; 244; -.
DR   GO; GO:0004966; F:galanin receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IEA:InterPro.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:GOC.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:1902608; P:positive regulation of large conductance calcium-activated potassium channel activity; IMP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GALR3_HUMAN             Reviewed;         368 AA.
AC   O60755; Q53YJ4;
DE   RecName: Full=Galanin receptor type 3;
DE            Short=GAL3-R;
DE            Short=GALR-3;
GN   Name=GALR3; Synonyms=GALNR3;
DR   GuidetoPHARMACOLOGY; 245; -.
DR   GO; GO:0004966; F:galanin receptor activity; TAS:ProtInc.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; TAS:ProtInc.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GALT1_HUMAN             Reviewed;         559 AA.
AC   Q10472; Q86TJ7; Q9UM86;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 1;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 1;
DE            Short=GalNAc-T1;
DE            Short=pp-GaNTase 1;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 1;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1;
DE   Contains:
DE     RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 1 soluble form;
GN   Name=GALNT1;
DR   GO; GO:0030145; F:manganese ion binding; IDA:BHF-UCL.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; ISS:UniProtKB.
DR   GO; GO:0018242; P:protein O-linked glycosylation via serine; IDA:BHF-UCL.
DR   GO; GO:0018243; P:protein O-linked glycosylation via threonine; IDA:BHF-UCL.
//
ID   GALT2_HUMAN             Reviewed;         571 AA.
AC   Q10471; A8K1Y3; C5HU00; Q9NPY4;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 2;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 2;
DE            Short=GalNAc-T2;
DE            Short=pp-GaNTase 2;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 2;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2;
DE   Contains:
DE     RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 2 soluble form;
GN   Name=GALNT2;
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0002378; P:immunoglobulin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0018242; P:protein O-linked glycosylation via serine; IDA:BHF-UCL.
DR   GO; GO:0018243; P:protein O-linked glycosylation via threonine; IDA:BHF-UCL.
//
ID   GALT3_HUMAN             Reviewed;         633 AA.
AC   Q14435; Q53TG9; Q7Z476;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 3;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 3;
DE            Short=GalNAc-T3;
DE            Short=pp-GaNTase 3;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 3;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3;
GN   Name=GALNT3;
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0030145; F:manganese ion binding; IDA:BHF-UCL.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018242; P:protein O-linked glycosylation via serine; IDA:BHF-UCL.
DR   GO; GO:0018243; P:protein O-linked glycosylation via threonine; IDA:UniProtKB.
//
ID   GALT4_HUMAN             Reviewed;         578 AA.
AC   Q8N4A0; B2R775; B4DMX6; O00208;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 4;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 4;
DE            Short=GalNAc-T4;
DE            Short=pp-GaNTase 4;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 4;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4;
GN   Name=GALNT4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GALT5_HUMAN             Reviewed;         940 AA.
AC   Q7Z7M9; A5PKZ1; Q9UGK7; Q9UHL6;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 5;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 5;
DE            Short=GalNAc-T5;
DE            Short=pp-GaNTase 5;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 5;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5;
GN   Name=GALNT5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GALT6_HUMAN             Reviewed;         622 AA.
AC   Q8NCL4; Q8IYH4; Q9H6G2; Q9UIV5;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 6;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 6;
DE            Short=GalNAc-T6;
DE            Short=pp-GaNTase 6;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 6;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6;
GN   Name=GALNT6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; TAS:ProtInc.
//
ID   GALT7_HUMAN             Reviewed;         657 AA.
AC   Q86SF2; B3KQU3; Q7Z5W7; Q9UJ28;
DE   RecName: Full=N-acetylgalactosaminyltransferase 7;
DE            EC=2.4.1.-;
DE   AltName: Full=Polypeptide GalNAc transferase 7;
DE            Short=GalNAc-T7;
DE            Short=pp-GaNTase 7;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 7;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7;
GN   Name=GALNT7;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; TAS:ProtInc.
//
ID   GALT8_HUMAN             Reviewed;         637 AA.
AC   Q9NY28; B2RU02;
DE   RecName: Full=Probable polypeptide N-acetylgalactosaminyltransferase 8;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 8;
DE            Short=GalNAc-T8;
DE            Short=pp-GaNTase 8;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 8;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8;
GN   Name=GALNT8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GALT9_HUMAN             Reviewed;         603 AA.
AC   Q9HCQ5; Q52LR8; Q6NT54; Q8NFR1;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 9;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 9;
DE            Short=GalNAc-T9;
DE            Short=pp-GaNTase 9;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 9;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9;
GN   Name=GALNT9;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; NAS:UniProtKB.
//
ID   GALT_HUMAN              Reviewed;         379 AA.
AC   P07902; B4E097; E7ET32; Q14355; Q14356; Q14357; Q14358; Q14359;
AC   Q14360; Q14361; Q14363; Q14364; Q14365; Q14369; Q14370; Q14371;
AC   Q14372; Q14373; Q14374; Q14375; Q14377; Q14378; Q14380; Q14381;
AC   Q14382; Q14383; Q14384; Q14385; Q14386; Q14387; Q14389; Q16766;
AC   Q53XK1; Q5VZ81; Q96BY1;
DE   RecName: Full=Galactose-1-phosphate uridylyltransferase;
DE            Short=Gal-1-P uridylyltransferase;
DE            EC=2.7.7.12;
DE   AltName: Full=UDP-glucose--hexose-1-phosphate uridylyltransferase;
GN   Name=GALT;
DR   GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019388; P:galactose catabolic process; TAS:Reactome.
DR   GO; GO:0006012; P:galactose metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006258; P:UDP-glucose catabolic process; IEA:Ensembl.
//
ID   GAMT_HUMAN              Reviewed;         236 AA.
AC   Q14353; A8K0A0; Q53Y34; Q8WVJ1;
DE   RecName: Full=Guanidinoacetate N-methyltransferase;
DE            EC=2.1.1.2;
GN   Name=GAMT;
DR   GO; GO:0030731; F:guanidinoacetate N-methyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0008168; F:methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006601; P:creatine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   GANAB_HUMAN             Reviewed;         944 AA.
AC   Q14697; A6NC20; Q8WTS9; Q9P0X0;
DE   RecName: Full=Neutral alpha-glucosidase AB;
DE            EC=3.2.1.84;
DE   AltName: Full=Alpha-glucosidase 2;
DE   AltName: Full=Glucosidase II subunit alpha;
DE   Flags: Precursor;
GN   Name=GANAB; Synonyms=G2AN, KIAA0088;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0033919; F:glucan 1,3-alpha-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   GANC_HUMAN              Reviewed;         914 AA.
AC   Q8TET4; Q52LQ4; Q8IWZ0; Q8IZM4; Q8IZM5;
DE   RecName: Full=Neutral alpha-glucosidase C;
DE            EC=3.2.1.20;
GN   Name=GANC;
DR   GO; GO:0004558; F:alpha-glucosidase activity; NAS:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0032450; F:maltose alpha-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   GANP_HUMAN              Reviewed;        1980 AA.
AC   O60318; C9JL56; Q2M3C1; Q6PJP6; Q9BSY5; Q9UMT4;
DE   RecName: Full=Germinal-center associated nuclear protein;
DE            Short=GANP;
DE   AltName: Full=80 kDa MCM3-associated protein;
DE   AltName: Full=MCM3 acetylating protein;
DE            Short=MCM3AP;
DE            EC=2.3.1.-;
DE   AltName: Full=MCM3 acetyltransferase;
GN   Name=MCM3AP; Synonyms=GANP, KIAA0572, MAP80;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006606; P:protein import into nucleus; TAS:ProtInc.
//
ID   GAN_HUMAN               Reviewed;         597 AA.
AC   Q9H2C0;
DE   RecName: Full=Gigaxonin;
DE   AltName: Full=Kelch-like protein 16;
GN   Name=GAN; Synonyms=GAN1, KLHL16;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   GAPD1_HUMAN             Reviewed;        1478 AA.
AC   Q14C86; A8MYK3; B0QZ62; B0QZ63; B0QZ64; Q14C76; Q2Q1W1; Q8ND92;
AC   Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0;
DE   RecName: Full=GTPase-activating protein and VPS9 domain-containing protein 1;
DE   AltName: Full=GAPex-5;
DE   AltName: Full=Rab5-activating protein 6;
GN   Name=GAPVD1; Synonyms=GAPEX5, KIAA1521, RAP6;
DR   GO; GO:0032794; F:GTPase activating protein binding; IMP:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0043087; P:regulation of GTPase activity; IMP:GOC.
DR   GO; GO:0051223; P:regulation of protein transport; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   GAPR1_HUMAN             Reviewed;         154 AA.
AC   Q9H4G4; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36;
DE   RecName: Full=Golgi-associated plant pathogenesis-related protein 1;
DE            Short=GAPR-1;
DE            Short=Golgi-associated PR-1 protein;
DE   AltName: Full=Glioma pathogenesis-related protein 2;
DE            Short=GliPR 2;
GN   Name=GLIPR2; Synonyms=C9orf19, GAPR1;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProt.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProt.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProt.
//
ID   GAPT_HUMAN              Reviewed;         157 AA.
AC   Q8N292;
DE   RecName: Full=Protein GAPT;
DE   AltName: Full=Growth factor receptor-bound protein 2-binding adapter protein, transmembrane;
GN   Name=GAPT; Synonyms=C5orf29;
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
//
ID   GAR1_HUMAN              Reviewed;         217 AA.
AC   Q9NY12; Q5MJQ2;
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit 1;
DE   AltName: Full=Nucleolar protein family A member 1;
DE   AltName: Full=snoRNP protein GAR1;
GN   Name=GAR1; Synonyms=NOLA1;
DR   GO; GO:0005261; F:cation channel activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006812; P:cation transport; TAS:GOC.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   GAREL_HUMAN             Reviewed;         874 AA.
AC   Q75VX8; B5MC97; B7WNK9; Q8NF27; Q9UIK8;
DE   RecName: Full=GRB2-associated and regulator of MAPK protein-like;
DE   AltName: Full=GRB2-associated and regulator of MAPK1-like;
GN   Name=GAREML; Synonyms=FAM59B, KIAA2038; ORFNames=HRIHFB2063;
//
ID   GAREM_HUMAN             Reviewed;         876 AA.
AC   Q9H706; Q0VAG3; Q0VAG4; Q8ND03; Q9BSF5;
DE   RecName: Full=GRB2-associated and regulator of MAPK protein;
DE   AltName: Full=GRB2-associated and regulator of MAPK1;
GN   Name=GAREM; Synonyms=C18orf11, FAM59A;
DR   GO; GO:0070064; F:proline-rich region binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
//
ID   GARL3_HUMAN             Reviewed;        1013 AA.
AC   Q5VVW2; B4DEP7; B7Z3Q6; Q8IYU1; Q8N951; Q8ND89; Q9BQH6;
DE   RecName: Full=GTPase-activating Rap/Ran-GAP domain-like protein 3;
GN   Name=GARNL3;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   GAS1_HUMAN              Reviewed;         345 AA.
AC   P54826; B9EGM4; Q6B086;
DE   RecName: Full=Growth arrest-specific protein 1;
DE            Short=GAS-1;
DE   Flags: Precursor;
GN   Name=GAS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0045165; P:cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEP:UniProtKB.
DR   GO; GO:0021587; P:cerebellum morphogenesis; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; ISS:UniProtKB.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048592; P:eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0010955; P:negative regulation of protein processing; IMP:UniProtKB.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0042473; P:outer ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0012501; P:programmed cell death; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IMP:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
//
ID   GAS2_HUMAN              Reviewed;         313 AA.
AC   O43903; B2R9C8; D3DQZ0; Q6ICV8;
DE   RecName: Full=Growth arrest-specific protein 2;
DE            Short=GAS-2;
GN   Name=GAS2;
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
//
ID   GAS6_HUMAN              Reviewed;         721 AA.
AC   Q14393; B3KRQ7; B3KVL4; E9PBL7; Q6IMN1; Q7Z7N3;
DE   RecName: Full=Growth arrest-specific protein 6;
DE            Short=GAS-6;
DE   AltName: Full=AXL receptor tyrosine kinase ligand;
DE   Flags: Precursor;
GN   Name=GAS6; Synonyms=AXLLG;
DR   GO; GO:0060090; F:binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0048018; F:receptor agonist activity; IDA:MGI.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; ISS:UniProtKB.
DR   GO; GO:0043277; P:apoptotic cell clearance; IDA:UniProtKB.
DR   GO; GO:0035754; P:B cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0031589; P:cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0071307; P:cellular response to vitamin K; IDA:UniProtKB.
DR   GO; GO:0097028; P:dendritic cell differentiation; IEP:UniProtKB.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0085029; P:extracellular matrix assembly; ISS:UniProtKB.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IDA:UniProtKB.
DR   GO; GO:0097241; P:hematopoietic stem cell migration to bone marrow; IDA:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0010934; P:macrophage cytokine production; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0070168; P:negative regulation of biomineral tissue development; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000669; P:negative regulation of dendritic cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0050711; P:negative regulation of interleukin-1 secretion; IDA:UniProtKB.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:UniProtKB.
DR   GO; GO:1900165; P:negative regulation of interleukin-6 secretion; IDA:UniProtKB.
DR   GO; GO:1900142; P:negative regulation of oligodendrocyte apoptotic process; IDA:UniProtKB.
DR   GO; GO:0033159; P:negative regulation of protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:2000533; P:negative regulation of renal albumin absorption; ISS:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; TAS:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:2000510; P:positive regulation of dendritic cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:MGI.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0003104; P:positive regulation of glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IDA:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0043491; P:protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
DR   GO; GO:0046813; P:receptor-mediated virion attachment to host cell; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0046718; P:viral entry into host cell; IDA:UniProtKB.
DR   GO; GO:0019079; P:viral genome replication; IDA:UniProtKB.
//
ID   GAS7_HUMAN              Reviewed;         476 AA.
AC   O60861; A8KAC2; B2RCK9; O43144; Q53Y77; Q7Z571;
DE   RecName: Full=Growth arrest-specific protein 7;
DE            Short=GAS-7;
GN   Name=GAS7; Synonyms=KIAA0394;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
//
ID   GAS8_HUMAN              Reviewed;         478 AA.
AC   O95995; B2RCT1; B7Z4U1; G3V1L5; Q2M234;
DE   RecName: Full=Growth arrest-specific protein 8;
DE            Short=GAS-8;
DE   AltName: Full=Growth arrest-specific protein 11;
DE            Short=GAS-11;
GN   Name=GAS8; Synonyms=GAS11;
DR   GO; GO:0048870; P:cell motility; IEA:InterPro.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
//
ID   GASP1_HUMAN             Reviewed;        1395 AA.
AC   Q5JY77; O43168; Q96LA1;
DE   RecName: Full=G-protein coupled receptor-associated sorting protein 1;
DE            Short=GASP-1;
GN   Name=GPRASP1; Synonyms=GASP, KIAA0443;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:1990172; P:G-protein coupled receptor catabolic process; IMP:UniProtKB.
//
ID   GASP2_HUMAN             Reviewed;         838 AA.
AC   Q96D09; D3DXA0; Q8NAB4;
DE   RecName: Full=G-protein coupled receptor-associated sorting protein 2;
DE            Short=GASP-2;
GN   Name=GPRASP2;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
//
ID   GASR_HUMAN              Reviewed;         447 AA.
AC   P32239; A8K7P9; O75824; Q16144; Q92492; Q96LC6; Q9NYK7; Q9UBV1;
DE   RecName: Full=Gastrin/cholecystokinin type B receptor;
DE            Short=CCK-B receptor;
DE            Short=CCK-BR;
DE   AltName: Full=Cholecystokinin-2 receptor;
DE            Short=CCK2-R;
GN   Name=CCKBR; Synonyms=CCKRB;
DR   GuidetoPHARMACOLOGY; 77; -.
DR   GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; TAS:ProtInc.
DR   GO; GO:0004951; F:cholecystokinin receptor activity; TAS:ProtInc.
DR   GO; GO:0015054; F:gastrin receptor activity; IDA:UniProtKB.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031741; F:type B gastrin/cholecystokinin receptor binding; IDA:NTNU_SB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0038188; P:cholecystokinin signaling pathway; TAS:GOC.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0001696; P:gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0048732; P:gland development; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; TAS:GOC.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
//
ID   GAST_HUMAN              Reviewed;         101 AA.
AC   P01350; P78463; P78464;
DE   RecName: Full=Gastrin;
DE   Contains:
DE     RecName: Full=Gastrin-71;
DE     AltName: Full=Gastrin component I;
DE   Contains:
DE     RecName: Full=Gastrin-52;
DE              Short=G52;
DE   Contains:
DE     RecName: Full=Big gastrin;
DE     AltName: Full=Gastrin component II;
DE     AltName: Full=Gastrin-34;
DE              Short=G34;
DE   Contains:
DE     RecName: Full=Gastrin;
DE     AltName: Full=Gastrin component III;
DE     AltName: Full=Gastrin-17;
DE              Short=G17;
DE   Contains:
DE     RecName: Full=Gastrin-14;
DE              Short=G14;
DE   Contains:
DE     RecName: Full=Gastrin-6;
DE              Short=G6;
DE   Flags: Precursor;
GN   Name=GAST; Synonyms=GAS;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   GATA1_HUMAN             Reviewed;         413 AA.
AC   P15976; Q96GB8;
DE   RecName: Full=Erythroid transcription factor;
DE   AltName: Full=Eryf1;
DE   AltName: Full=GATA-binding factor 1;
DE            Short=GATA-1;
DE            Short=GF-1;
DE   AltName: Full=NF-E1 DNA-binding protein;
GN   Name=GATA1; Synonyms=ERYF1, GF1;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:BHF-UCL.
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IEA:Ensembl.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IMP:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IMP:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030221; P:basophil differentiation; IEP:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0097028; P:dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030222; P:eosinophil differentiation; IEP:BHF-UCL.
DR   GO; GO:0035854; P:eosinophil fate commitment; IDA:BHF-UCL.
DR   GO; GO:0048821; P:erythrocyte development; IMP:BHF-UCL.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IMP:BHF-UCL.
DR   GO; GO:0030219; P:megakaryocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0070527; P:platelet aggregation; IMP:BHF-UCL.
DR   GO; GO:0030220; P:platelet formation; IMP:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0010724; P:regulation of definitive erythrocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0010559; P:regulation of glycoprotein biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0071733; P:transcriptional activation by promoter-enhancer looping; ISS:BHF-UCL.
//
ID   GATA2_HUMAN             Reviewed;         480 AA.
AC   P23769; D3DNB3; Q53YE0; Q96BH0; Q96BH8; Q9BUJ6;
DE   RecName: Full=Endothelial transcription factor GATA-2;
DE   AltName: Full=GATA-binding protein 2;
GN   Name=GATA2;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IDA:MGI.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0021533; P:cell differentiation in hindbrain; IEA:Ensembl.
DR   GO; GO:0001709; P:cell fate determination; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0035854; P:eosinophil fate commitment; IDA:BHF-UCL.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.
DR   GO; GO:0070345; P:negative regulation of fat cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; IEA:Ensembl.
DR   GO; GO:2000178; P:negative regulation of neural precursor cell proliferation; IDA:MGI.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:MGI.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:MGI.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0035065; P:regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0060872; P:semicircular canal development; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; IEA:Ensembl.
DR   GO; GO:0021514; P:ventral spinal cord interneuron differentiation; IEA:Ensembl.
//
ID   GATA3_HUMAN             Reviewed;         443 AA.
AC   P23771; Q5VWG7; Q5VWG8; Q96J16;
DE   RecName: Full=Trans-acting T-cell-specific transcription factor GATA-3;
DE   AltName: Full=GATA-binding factor 3;
GN   Name=GATA3;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0071837; F:HMG box domain binding; IPI:UniProtKB.
DR   GO; GO:0001071; F:nucleic acid binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0003180; P:aortic valve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0061290; P:canonical Wnt signaling pathway involved in metanephric kidney development; ISS:UniProtKB.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; ISS:UniProtKB.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IEP:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEP:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0043583; P:ear development; IMP:UniProtKB.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0072643; P:interferon-gamma secretion; IEA:Ensembl.
DR   GO; GO:0072602; P:interleukin-4 secretion; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IMP:UniProtKB.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0072676; P:lymphocyte migration; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; ISS:UniProtKB.
DR   GO; GO:0060374; P:mast cell differentiation; IEA:Ensembl.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; IDA:UniProtKB.
DR   GO; GO:0001823; P:mesonephros development; ISS:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:2000146; P:negative regulation of cell motility; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:2000607; P:negative regulation of cell proliferation involved in mesonephros development; ISS:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IMP:UniProtKB.
DR   GO; GO:2000703; P:negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.
DR   GO; GO:2000734; P:negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation; ISS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0072179; P:nephric duct formation; ISS:UniProtKB.
DR   GO; GO:0072178; P:nephric duct morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0071599; P:otic vesicle development; IEA:Ensembl.
DR   GO; GO:0060017; P:parathyroid gland development; IEA:Ensembl.
DR   GO; GO:0035898; P:parathyroid hormone secretion; IEA:Ensembl.
DR   GO; GO:0060037; P:pharyngeal system development; ISS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0032736; P:positive regulation of interleukin-13 production; IEA:Ensembl.
DR   GO; GO:2000667; P:positive regulation of interleukin-13 secretion; IDA:UniProtKB.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0032754; P:positive regulation of interleukin-5 production; IEA:Ensembl.
DR   GO; GO:2000664; P:positive regulation of interleukin-5 secretion; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IMP:UniProtKB.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000611; P:positive regulation of thyroid hormone generation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0002572; P:pro-T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043370; P:regulation of CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:2000683; P:regulation of cellular response to X-ray; IMP:UniProtKB.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0061085; P:regulation of histone H3-K27 methylation; IEA:Ensembl.
DR   GO; GO:0051569; P:regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0072182; P:regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEP:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045064; P:T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0045061; P:thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0031929; P:TOR signaling; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0001806; P:type IV hypersensitivity; IEA:Ensembl.
DR   GO; GO:0035799; P:ureter maturation; IEA:Ensembl.
DR   GO; GO:0060676; P:ureteric bud formation; ISS:UniProtKB.
DR   GO; GO:0060065; P:uterus development; ISS:UniProtKB.
DR   GO; GO:0003281; P:ventricular septum development; ISS:UniProtKB.
//
ID   GATA4_HUMAN             Reviewed;         442 AA.
AC   P43694; B7ZKX0; Q3MJ45; Q5IFM8;
DE   RecName: Full=Transcription factor GATA-4;
DE   AltName: Full=GATA-binding factor 4;
GN   Name=GATA4;
DR   GO; GO:0033613; F:activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003289; P:atrial septum primum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003290; P:atrial septum secundum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0061049; P:cell growth involved in cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:BHF-UCL.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035054; P:embryonic heart tube anterior/posterior pattern specification; ISS:BHF-UCL.
DR   GO; GO:0003197; P:endocardial cushion development; IMP:BHF-UCL.
DR   GO; GO:0007492; P:endoderm development; TAS:BHF-UCL.
DR   GO; GO:0001706; P:endoderm formation; IEA:Ensembl.
DR   GO; GO:0072148; P:epithelial cell fate commitment; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060575; P:intestinal epithelial cell differentiation; IDA:MGI.
DR   GO; GO:0060464; P:lung lobe formation; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IMP:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051891; P:positive regulation of cardioblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:BHF-UCL.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IMP:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0072520; P:seminiferous tubule development; IEA:Ensembl.
DR   GO; GO:0060008; P:Sertoli cell differentiation; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0003229; P:ventricular cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; ISS:BHF-UCL.
//
ID   GATA5_HUMAN             Reviewed;         397 AA.
AC   Q9BWX5; Q17RE2;
DE   RecName: Full=Transcription factor GATA-5;
DE   AltName: Full=GATA-binding factor 5;
GN   Name=GATA5;
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0060575; P:intestinal epithelial cell differentiation; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   GATA6_HUMAN             Reviewed;         595 AA.
AC   Q92908; B0YJ17; P78327;
DE   RecName: Full=Transcription factor GATA-6;
DE   AltName: Full=GATA-binding factor 6;
GN   Name=GATA6;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0060947; P:cardiac vascular smooth muscle cell differentiation; IMP:UniProtKB.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0060486; P:Clara cell differentiation; IEA:Ensembl.
DR   GO; GO:0007493; P:endodermal cell fate determination; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060575; P:intestinal epithelial cell differentiation; IDA:MGI.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0060430; P:lung saccule development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032911; P:negative regulation of transforming growth factor beta1 production; IMP:UniProtKB.
DR   GO; GO:0032912; P:negative regulation of transforming growth factor beta2 production; IMP:UniProtKB.
DR   GO; GO:0048645; P:organ formation; IEA:Ensembl.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003310; P:pancreatic A cell differentiation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051891; P:positive regulation of cardioblast differentiation; IEA:Ensembl.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0070848; P:response to growth factor; IDA:UniProtKB.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IMP:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0035239; P:tube morphogenesis; IEA:Ensembl.
DR   GO; GO:0003309; P:type B pancreatic cell differentiation; IEA:Ensembl.
DR   GO; GO:0060510; P:Type II pneumocyte differentiation; IEA:Ensembl.
//
ID   GATA_HUMAN              Reviewed;         528 AA.
AC   Q9H0R6; Q5VWJ4; Q9HA60; Q9NV19;
DE   RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial;
DE            Short=Glu-AdT subunit A;
DE            EC=6.3.5.7;
DE   AltName: Full=Glutaminyl-tRNA synthase-like protein 1;
GN   Name=QRSL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050567; F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0070681; P:glutaminyl-tRNAGln biosynthesis via transamidation; IDA:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; IMP:UniProtKB.
//
ID   GATB_HUMAN              Reviewed;         557 AA.
AC   O75879; Q4W5M8; Q9P0S6; Q9Y2B8;
DE   RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial;
DE            Short=Glu-AdT subunit B;
DE            EC=6.3.5.-;
DE   AltName: Full=Cytochrome c oxidase assembly factor PET112 homolog;
DE   Flags: Precursor;
GN   Name=PET112; Synonyms=PET112L; ORFNames=HSPC199;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050567; F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0070681; P:glutaminyl-tRNAGln biosynthesis via transamidation; IDA:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; IMP:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   GATC_HUMAN              Reviewed;         136 AA.
AC   O43716; B3KSU7; Q3B824; Q3KNR8;
DE   RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial;
DE            Short=Glu-AdT subunit C;
DE            EC=6.3.5.-;
DE   AltName: Full=Protein 15E1.2;
DE   Flags: Precursor;
GN   Name=GATC; Synonyms=15E1.2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050567; F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0070681; P:glutaminyl-tRNAGln biosynthesis via transamidation; IDA:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; IMP:UniProtKB.
DR   GO; GO:0006450; P:regulation of translational fidelity; IEA:InterPro.
//
ID   GATD1_HUMAN             Reviewed;         269 AA.
AC   Q8WUU5; B2RE37; D6W5Q5; Q8N5Y5; Q99995; Q9H689;
DE   RecName: Full=GATA zinc finger domain-containing protein 1;
DE   AltName: Full=Ocular development-associated gene protein;
GN   Name=GATAD1; Synonyms=ODAG;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   GATL1_HUMAN             Reviewed;         329 AA.
AC   A6NNH0;
DE   RecName: Full=GATS-like protein 1;
GN   Name=GATSL1;
//
ID   GATL2_HUMAN             Reviewed;         329 AA.
AC   A6NHX0; B9EJH9;
DE   RecName: Full=GATS-like protein 2;
GN   Name=GATSL2;
//
ID   GATL3_HUMAN             Reviewed;         329 AA.
AC   Q8WTX7; O76052; Q96ND9; Q9UIE8;
DE   RecName: Full=GATS-like protein 3;
GN   Name=GATSL3;
//
ID   GATM_HUMAN              Reviewed;         423 AA.
AC   P50440; B4DH99; B4DPI3; Q53EQ4;
DE   RecName: Full=Glycine amidinotransferase, mitochondrial;
DE            EC=2.1.4.1;
DE   AltName: Full=L-arginine:glycine amidinotransferase;
DE   AltName: Full=Transamidinase;
DE   Flags: Precursor;
GN   Name=GATM; Synonyms=AGAT;
DR   GO; GO:0015068; F:glycine amidinotransferase activity; IDA:MGI.
DR   GO; GO:0016813; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006601; P:creatine biosynthetic process; IDA:MGI.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0046689; P:response to mercury ion; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
//
ID   GATS_HUMAN              Reviewed;         163 AA.
AC   Q8NAP1; D6W5V0; Q68D93; Q6P198; Q6PII7; Q7Z720; Q86UK9;
DE   RecName: Full=Putative protein GATS;
DE   AltName: Full=STAG3 opposite strand transcript protein;
GN   Name=GATS; Synonyms=STAG3OS;
//
ID   GBA2_HUMAN              Reviewed;         927 AA.
AC   Q9HCG7; D3DRP2; Q5TCV6; Q96A51; Q96LY1; Q96SJ2; Q9H2L8;
DE   RecName: Full=Non-lysosomal glucosylceramidase;
DE            Short=NLGase;
DE            EC=3.2.1.45;
DE   AltName: Full=Beta-glucocerebrosidase 2;
DE            Short=Beta-glucosidase 2;
DE   AltName: Full=Glucosylceramidase 2;
GN   Name=GBA2; Synonyms=KIAA1605; ORFNames=AD035;
DR   GO; GO:0008422; F:beta-glucosidase activity; IDA:UniProtKB.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008206; P:bile acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0021954; P:central nervous system neuron development; IMP:UniProtKB.
DR   GO; GO:0006680; P:glucosylceramide catabolic process; IEA:InterPro.
DR   GO; GO:0016139; P:glycoside catabolic process; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   GBA3_HUMAN              Reviewed;         469 AA.
AC   Q9H227; Q32LY7; Q3MIH4; Q53GG8; Q6NSF4; Q8NHT8; Q9H3T4; Q9H4C6;
DE   RecName: Full=Cytosolic beta-glucosidase;
DE            EC=3.2.1.21;
DE   AltName: Full=Cytosolic beta-glucosidase-like protein 1;
GN   Name=GBA3; Synonyms=CBG, CBGL1;
DR   GO; GO:0004565; F:beta-galactosidase activity; IDA:UniProtKB.
DR   GO; GO:0008422; F:beta-glucosidase activity; IDA:UniProtKB.
DR   GO; GO:0017042; F:glycosylceramidase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0016139; P:glycoside catabolic process; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0046477; P:glycosylceramide catabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   GBB1_HUMAN              Reviewed;         340 AA.
AC   P62873; B1AJZ7; P04697; P04901;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;
DE   AltName: Full=Transducin beta chain 1;
GN   Name=GNB1;
DR   GO; GO:0003924; F:GTPase activity; IDA:MGI.
DR   GO; GO:0051020; F:GTPase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0010659; P:cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071870; P:cellular response to catecholamine stimulus; ISS:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBB2_HUMAN              Reviewed;         340 AA.
AC   P62879; P11016; P54312;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2;
DE   AltName: Full=G protein subunit beta-2;
DE   AltName: Full=Transducin beta chain 2;
GN   Name=GNB2;
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0051020; F:GTPase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBB3_HUMAN              Reviewed;         340 AA.
AC   P16520; Q9BQC0;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;
DE   AltName: Full=Transducin beta chain 3;
GN   Name=GNB3;
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0051020; F:GTPase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBB4_HUMAN              Reviewed;         340 AA.
AC   Q9HAV0; B3KMH5; D3DNR8;
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-4;
DE   AltName: Full=Transducin beta chain 4;
GN   Name=GNB4;
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   GBB5_HUMAN              Reviewed;         395 AA.
AC   O14775; B2RBR5; Q9HAU9; Q9UFT3;
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-5;
DE   AltName: Full=Gbeta5;
DE   AltName: Full=Transducin beta chain 5;
GN   Name=GNB5;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProt.
DR   GO; GO:0031682; F:G-protein gamma-subunit binding; IPI:UniProt.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:1901386; P:negative regulation of voltage-gated calcium channel activity; IDA:UniProt.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   GBF1_HUMAN              Reviewed;        1859 AA.
AC   Q92538; Q5VXX3; Q96CK6; Q96HZ3; Q9H473;
DE   RecName: Full=Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1;
DE            Short=BFA-resistant GEF 1;
GN   Name=GBF1; Synonyms=KIAA0248;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:RefGenome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   GBG10_HUMAN             Reviewed;          68 AA.
AC   P50151; Q3B7K2; Q4VC27;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10;
DE   Flags: Precursor;
GN   Name=GNG10; Synonyms=GNGT10;
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG11_HUMAN             Reviewed;          73 AA.
AC   P61952; P50152;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11;
DE   Flags: Precursor;
GN   Name=GNG11; Synonyms=GNGT11;
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GBG12_HUMAN             Reviewed;          72 AA.
AC   Q9UBI6; Q69YP5; Q9BRV5;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12;
DE   Flags: Precursor;
GN   Name=GNG12;
DR   GO; GO:0030165; F:PDZ domain binding; IDA:MGI.
DR   GO; GO:0042301; F:phosphate ion binding; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG13_HUMAN             Reviewed;          67 AA.
AC   Q9P2W3; B2R5C8; Q52LX0; Q9UJJ3;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13;
DE   Flags: Precursor;
GN   Name=GNG13;
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IPI:UniProt.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GBG1_HUMAN              Reviewed;          74 AA.
AC   P63211; A4D1H2; O43835; Q08447; Q16026; Q6LCP6;
DE   RecName: Full=Guanine nucleotide-binding protein G(T) subunit gamma-T1;
DE   AltName: Full=Transducin gamma chain;
DE   Flags: Precursor;
GN   Name=GNGT1;
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0010659; P:cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG2_HUMAN              Reviewed;          71 AA.
AC   P59768; Q5JPE2; Q6P9A9;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2;
DE   AltName: Full=G gamma-I;
DE   Flags: Precursor;
GN   Name=GNG2;
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IPI:UniProt.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071870; P:cellular response to catecholamine stimulus; ISS:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG3_HUMAN              Reviewed;          75 AA.
AC   P63215; B2R4S7; P29798; Q61014;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3;
DE   Flags: Precursor;
GN   Name=GNG3; Synonyms=GNGT3;
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG4_HUMAN              Reviewed;          75 AA.
AC   P50150;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4;
DE   Flags: Precursor;
GN   Name=GNG4; Synonyms=GNGT4;
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG5_HUMAN              Reviewed;          68 AA.
AC   P63218; B2R5A0; P30670; Q5VX54; Q61015;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5;
DE   Flags: Precursor;
GN   Name=GNG5; Synonyms=GNGT5;
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:MGI.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG7_HUMAN              Reviewed;          68 AA.
AC   O60262; B2R496;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7;
DE   Flags: Precursor;
GN   Name=GNG7; Synonyms=GNGT7;
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IEA:Ensembl.
DR   GO; GO:0045761; P:regulation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBG8_HUMAN              Reviewed;          70 AA.
AC   Q9UK08; Q4VBM5;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8;
DE   AltName: Full=Gamma-9;
DE   Flags: Precursor;
GN   Name=GNG8; Synonyms=GNG9, GNGT9;
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBGT1_HUMAN             Reviewed;         347 AA.
AC   Q8N5D6; A8K633; B2RA95; Q45F07; Q5T7U9; Q5T7V1; Q8N2K4; Q9UKI5;
DE   RecName: Full=Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1;
DE            EC=2.4.1.-;
DE   AltName: Full=Forssman glycolipid synthase-like protein;
GN   Name=GBGT1; ORFNames=UNQ2513/PRO6002;
DR   GO; GO:0047277; F:globoside alpha-N-acetylgalactosaminyltransferase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009247; P:glycolipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GBGT2_HUMAN             Reviewed;          69 AA.
AC   O14610; B2R746; D3DTW5;
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2;
DE   AltName: Full=G gamma-C;
DE   AltName: Full=G-gamma-8;
DE   AltName: Full=G-gamma-9;
DE   AltName: Full=Guanine nucleotide binding protein gamma transducing activity polypeptide 2;
DE   Flags: Precursor;
GN   Name=GNGT2; Synonyms=GNG8, GNG9, GNGT8;
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0007602; P:phototransduction; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GBLP_HUMAN              Reviewed;         317 AA.
AC   P63244; B3KTJ0; D3DWS0; P25388; P99049; Q53HU2; Q5J8M6; Q5VLR4;
AC   Q6FH47;
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1;
DE   AltName: Full=Cell proliferation-inducing gene 21 protein;
DE   AltName: Full=Guanine nucleotide-binding protein subunit beta-like protein 12.3;
DE   AltName: Full=Human lung cancer oncogene 7 protein;
DE            Short=HLC-7;
DE   AltName: Full=Receptor for activated C kinase;
DE   AltName: Full=Receptor of activated protein kinase C 1;
DE            Short=RACK1;
DE   Contains:
DE     RecName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed;
GN   Name=GNB2L1; ORFNames=HLC7, PIG21;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0008200; F:ion channel inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; TAS:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IDA:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0030292; F:protein tyrosine kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; NAS:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IDA:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007369; P:gastrulation; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IMP:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030822; P:positive regulation of cAMP catabolic process; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0051343; P:positive regulation of cyclic-nucleotide phosphodiesterase activity; IMP:BHF-UCL.
DR   GO; GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IMP:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0051302; P:regulation of cell division; ISS:UniProtKB.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0090003; P:regulation of establishment of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   GBP1_HUMAN              Reviewed;         592 AA.
AC   P32455; D3DT26; Q5T8M1;
DE   RecName: Full=Interferon-induced guanylate-binding protein 1;
DE   AltName: Full=GTP-binding protein 1;
DE            Short=GBP-1;
DE            Short=HuGBP-1;
DE   AltName: Full=Guanine nucleotide-binding protein 1;
DE   Flags: Precursor;
GN   Name=GBP1;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
//
ID   GBP2_HUMAN              Reviewed;         591 AA.
AC   P32456; Q6GPH0; Q6IAU2; Q86TB0;
DE   RecName: Full=Interferon-induced guanylate-binding protein 2;
DE   AltName: Full=GTP-binding protein 2;
DE            Short=GBP-2;
DE            Short=HuGBP-2;
DE   AltName: Full=Guanine nucleotide-binding protein 2;
DE   Flags: Precursor;
GN   Name=GBP2;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   GBP4_HUMAN              Reviewed;         640 AA.
AC   Q96PP9; B2R630; Q05D63; Q6NSL0; Q86T99;
DE   RecName: Full=Guanylate-binding protein 4;
DE   AltName: Full=GTP-binding protein 4;
DE            Short=GBP-4;
DE   AltName: Full=Guanine nucleotide-binding protein 4;
GN   Name=GBP4;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
//
ID   GBP3_HUMAN              Reviewed;         595 AA.
AC   Q9H0R5; A2A317; A6NF86; B2RTW0; F8UW81; Q05D54; Q5T8L8; Q5T8L9;
AC   Q6P3V3; Q9NV33;
DE   RecName: Full=Guanylate-binding protein 3;
DE   AltName: Full=GTP-binding protein 3;
DE            Short=GBP-3;
DE   AltName: Full=Guanine nucleotide-binding protein 3;
GN   Name=GBP3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
//
ID   GBP5_HUMAN              Reviewed;         586 AA.
AC   Q96PP8; B2RCE1; Q86TM5;
DE   RecName: Full=Guanylate-binding protein 5;
DE   AltName: Full=GBP-TA antigen;
DE   AltName: Full=GTP-binding protein 5;
DE            Short=GBP-5;
DE   AltName: Full=Guanine nucleotide-binding protein 5;
DE   Flags: Precursor;
GN   Name=GBP5; ORFNames=UNQ2427/PRO4987;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEA:Ensembl.
//
ID   GBP6_HUMAN              Reviewed;         633 AA.
AC   Q6ZN66; A2RRM3; Q6ZN86; Q7Z3F0;
DE   RecName: Full=Guanylate-binding protein 6;
DE   AltName: Full=GTP-binding protein 6;
DE            Short=GBP-6;
DE   AltName: Full=Guanine nucleotide-binding protein 6;
GN   Name=GBP6;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; ISS:UniProt.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProt.
DR   GO; GO:0006955; P:immune response; ISS:UniProt.
//
ID   GBP7_HUMAN              Reviewed;         638 AA.
AC   Q8N8V2;
DE   RecName: Full=Guanylate-binding protein 7;
DE   AltName: Full=GTP-binding protein 7;
DE            Short=GBP-7;
DE   AltName: Full=Guanine nucleotide-binding protein 7;
DE   AltName: Full=Guanylate-binding protein 4-like;
GN   Name=GBP7; Synonyms=GBP4L;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
//
ID   GBRA1_HUMAN             Reviewed;         456 AA.
AC   P14867; D3DQK6; Q8N629;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-1;
DE   AltName: Full=GABA(A) receptor subunit alpha-1;
DE   Flags: Precursor;
GN   Name=GABRA1;
DR   GuidetoPHARMACOLOGY; 404; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0008144; F:drug binding; ISS:BHF-UCL.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0051932; P:synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRA2_HUMAN             Reviewed;         451 AA.
AC   P47869; A8K0U7; B7Z1H8; Q59G14;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-2;
DE   AltName: Full=GABA(A) receptor subunit alpha-2;
DE   Flags: Precursor;
GN   Name=GABRA2;
DR   GuidetoPHARMACOLOGY; 405; -.
DR   GO; GO:0008503; F:benzodiazepine receptor activity; IMP:UniProtKB.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006836; P:neurotransmitter transport; IMP:UniProtKB.
DR   GO; GO:0001505; P:regulation of neurotransmitter levels; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GBRA3_HUMAN             Reviewed;         492 AA.
AC   P34903; Q8TAF9;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-3;
DE   AltName: Full=GABA(A) receptor subunit alpha-3;
DE   Flags: Precursor;
GN   Name=GABRA3;
DR   GuidetoPHARMACOLOGY; 406; -.
DR   GO; GO:0008503; F:benzodiazepine receptor activity; TAS:ProtInc.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRA4_HUMAN             Reviewed;         554 AA.
AC   P48169; Q8IYR7;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-4;
DE   AltName: Full=GABA(A) receptor subunit alpha-4;
DE   Flags: Precursor;
GN   Name=GABRA4;
DR   GuidetoPHARMACOLOGY; 407; -.
DR   GO; GO:0008503; F:benzodiazepine receptor activity; TAS:ProtInc.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:2001023; P:regulation of response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRA5_HUMAN             Reviewed;         462 AA.
AC   P31644; A8K338; Q14DC2; Q53XL6; Q9NYT3; Q9NYT4; Q9NYT5;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-5;
DE   AltName: Full=GABA(A) receptor subunit alpha-5;
DE   Flags: Precursor;
GN   Name=GABRA5;
DR   GuidetoPHARMACOLOGY; 408; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:Ensembl.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:InterPro.
DR   GO; GO:0060119; P:inner ear receptor cell development; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRA6_HUMAN             Reviewed;         453 AA.
AC   Q16445; A8K096; Q4VAV2;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit alpha-6;
DE   AltName: Full=GABA(A) receptor subunit alpha-6;
DE   Flags: Precursor;
GN   Name=GABRA6;
DR   GuidetoPHARMACOLOGY; 409; -.
DR   GO; GO:0008503; F:benzodiazepine receptor activity; TAS:ProtInc.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRAP_HUMAN             Reviewed;         117 AA.
AC   O95166;
DE   RecName: Full=Gamma-aminobutyric acid receptor-associated protein;
DE   AltName: Full=GABA(A) receptor-associated protein;
DE   AltName: Full=MM46;
DE   Flags: Precursor;
GN   Name=GABARAP; Synonyms=FLC3B; ORFNames=HT004;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0050811; F:GABA receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GBRB1_HUMAN             Reviewed;         474 AA.
AC   P18505; B2R6U7; Q16166; Q8TBK3;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit beta-1;
DE   AltName: Full=GABA(A) receptor subunit beta-1;
DE   Flags: Precursor;
GN   Name=GABRB1;
DR   GuidetoPHARMACOLOGY; 410; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRB2_HUMAN             Reviewed;         512 AA.
AC   P47870; A8K115; A8K1A0; D1LYT0; D1LYT1; Q16323; Q4FZB2;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit beta-2;
DE   AltName: Full=GABA(A) receptor subunit beta-2;
DE   Flags: Precursor;
GN   Name=GABRB2;
DR   GuidetoPHARMACOLOGY; 411; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0004890; F:GABA-A receptor activity; ISS:BHF-UCL.
DR   GO; GO:0005237; F:inhibitory extracellular ligand-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0060119; P:inner ear receptor cell development; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0051932; P:synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRB3_HUMAN             Reviewed;         473 AA.
AC   P28472; B7Z2W1; B7Z825; F5H3D2; H7BYV8; Q14352; Q96FM5;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit beta-3;
DE   AltName: Full=GABA(A) receptor subunit beta-3;
DE   Flags: Precursor;
GN   Name=GABRB3;
DR   GuidetoPHARMACOLOGY; 412; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0060119; P:inner ear receptor cell development; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRD_HUMAN              Reviewed;         452 AA.
AC   O14764; Q8N4N9;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit delta;
DE   AltName: Full=GABA(A) receptor subunit delta;
DE   Flags: Precursor;
GN   Name=GABRD;
DR   GuidetoPHARMACOLOGY; 416; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRE_HUMAN              Reviewed;         506 AA.
AC   P78334; O15345; O15346; Q99520;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit epsilon;
DE   AltName: Full=GABA(A) receptor subunit epsilon;
DE   Flags: Precursor;
GN   Name=GABRE;
DR   GuidetoPHARMACOLOGY; 417; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRG1_HUMAN             Reviewed;         465 AA.
AC   Q8N1C3; Q5H9T8;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit gamma-1;
DE   AltName: Full=GABA(A) receptor subunit gamma-1;
DE   Flags: Precursor;
GN   Name=GABRG1;
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   GBRG2_HUMAN             Reviewed;         467 AA.
AC   P18507; F5HB82; Q6GRL6; Q6PCC3; Q9UDB3; Q9UN15;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit gamma-2;
DE   AltName: Full=GABA(A) receptor subunit gamma-2;
DE   Flags: Precursor;
GN   Name=GABRG2;
DR   GuidetoPHARMACOLOGY; 414; -.
DR   GO; GO:0008503; F:benzodiazepine receptor activity; TAS:ProtInc.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0051932; P:synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRG3_HUMAN             Reviewed;         467 AA.
AC   Q99928; G3V594; Q9HD46; Q9NYT2;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit gamma-3;
DE   AltName: Full=GABA(A) receptor subunit gamma-3;
DE   Flags: Precursor;
GN   Name=GABRG3;
DR   GuidetoPHARMACOLOGY; 415; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GBRL1_HUMAN             Reviewed;         117 AA.
AC   Q9H0R8; B4E0Y7; Q6FIE6;
DE   RecName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1;
DE   AltName: Full=Early estrogen-regulated protein;
DE   AltName: Full=GABA(A) receptor-associated protein-like 1;
DE   AltName: Full=Glandular epithelial cell protein 1;
DE            Short=GEC-1;
DE   Flags: Precursor;
GN   Name=GABARAPL1; Synonyms=GEC1;
DR   GO; GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0050811; F:GABA receptor binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   GBRL2_HUMAN             Reviewed;         117 AA.
AC   P60520; O08765; Q6FG91; Q9DCP8; Q9UQF7;
DE   RecName: Full=Gamma-aminobutyric acid receptor-associated protein-like 2;
DE   AltName: Full=GABA(A) receptor-associated protein-like 2;
DE   AltName: Full=Ganglioside expression factor 2;
DE            Short=GEF-2;
DE   AltName: Full=General protein transport factor p16;
DE   AltName: Full=Golgi-associated ATPase enhancer of 16 kDa;
DE            Short=GATE-16;
DE   AltName: Full=MAP1 light chain 3-related protein;
DE   Flags: Precursor;
GN   Name=GABARAPL2; Synonyms=FLC3A, GEF2;
DR   GO; GO:0051117; F:ATPase binding; ISS:UniProtKB.
DR   GO; GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0050811; F:GABA receptor binding; ISS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000149; F:SNARE binding; ISS:UniProtKB.
DR   GO; GO:0006914; P:autophagy; NAS:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:1901799; P:negative regulation of proteasomal protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   GBRL3_HUMAN             Reviewed;         117 AA.
AC   Q9BY60;
DE   RecName: Full=Gamma-aminobutyric acid receptor-associated protein-like 3;
DE   AltName: Full=GABA(A) receptor-associated protein-like 3;
DE   Flags: Precursor;
GN   Name=GABARAPL3;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   GBRP_HUMAN              Reviewed;         440 AA.
AC   O00591; A8KA36; D3DQL2; Q32MJ1;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit pi;
DE   AltName: Full=GABA(A) receptor subunit pi;
DE   Flags: Precursor;
GN   Name=GABRP;
DR   GuidetoPHARMACOLOGY; 419; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   GBRR1_HUMAN             Reviewed;         479 AA.
AC   P24046; A1L401; B4DJK8; B4DQT5; B7ZBQ7; Q9BX06;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit rho-1;
DE   AltName: Full=GABA(A) receptor subunit rho-1;
DE   AltName: Full=GABA(C) receptor;
DE   Flags: Precursor;
GN   Name=GABRR1;
DR   GuidetoPHARMACOLOGY; 420; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GBRR2_HUMAN             Reviewed;         465 AA.
AC   P28476; A2BDE4; Q9H153;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit rho-2;
DE   AltName: Full=GABA(A) receptor subunit rho-2;
DE   AltName: Full=GABA(C) receptor;
DE   Flags: Precursor;
GN   Name=GABRR2;
DR   GuidetoPHARMACOLOGY; 421; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; TAS:ProtInc.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   GBRR3_HUMAN             Reviewed;         467 AA.
AC   A8MPY1; Q9UIV9;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit rho-3;
DE   AltName: Full=GABA(A) receptor subunit rho-3;
DE   AltName: Full=GABA(C) receptor;
DE   Flags: Precursor;
GN   Name=GABRR3;
DR   GuidetoPHARMACOLOGY; 422; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; NAS:UniProtKB.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; NAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GBRT_HUMAN              Reviewed;         632 AA.
AC   Q9UN88; A6NFN1; Q32MB4; Q9NZK8;
DE   RecName: Full=Gamma-aminobutyric acid receptor subunit theta;
DE   AltName: Full=GABA(A) receptor subunit theta;
DE   Flags: Precursor;
GN   Name=GABRQ;
DR   GuidetoPHARMACOLOGY; 418; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004890; F:GABA-A receptor activity; IEA:InterPro.
DR   GO; GO:0005326; F:neurotransmitter transporter activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006836; P:neurotransmitter transport; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GBX1_HUMAN              Reviewed;         363 AA.
AC   Q14549;
DE   RecName: Full=Homeobox protein GBX-1;
DE   AltName: Full=Gastrulation and brain-specific homeobox protein 1;
GN   Name=GBX1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0019230; P:proprioception; IEA:Ensembl.
DR   GO; GO:0097374; P:sensory neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GBX2_HUMAN              Reviewed;         348 AA.
AC   P52951; B2RPH7; O43833; Q53RX5; Q9Y5Y1;
DE   RecName: Full=Homeobox protein GBX-2;
DE   AltName: Full=Gastrulation and brain-specific homeobox protein 2;
GN   Name=GBX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0048483; P:autonomic nervous system development; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0021930; P:cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0021555; P:midbrain-hindbrain boundary morphogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0021568; P:rhombomere 2 development; IEA:Ensembl.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GC224_HUMAN             Reviewed;          35 AA.
AC   Q8WZA8;
DE   RecName: Full=Putative gastric cancer-related gene 224 protein;
DE            Short=GCRG-224;
DE            Short=GCRG-p224;
GN   Name=GCRG224;
//
ID   GCC1_HUMAN              Reviewed;         775 AA.
AC   Q96CN9; Q9H6N7;
DE   RecName: Full=GRIP and coiled-coil domain-containing protein 1;
DE   AltName: Full=Golgi coiled-coil protein 1;
GN   Name=GCC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   GCC2_HUMAN              Reviewed;        1684 AA.
AC   Q8IWJ2; A6H8X8; O15045; Q4ZG46; Q8TDH3; Q9H2G8;
DE   RecName: Full=GRIP and coiled-coil domain-containing protein 2;
DE   AltName: Full=185 kDa Golgi coiled-coil protein;
DE            Short=GCC185;
DE   AltName: Full=CLL-associated antigen KW-11;
DE   AltName: Full=CTCL tumor antigen se1-1;
DE   AltName: Full=Ran-binding protein 2-like 4;
DE            Short=RanBP2L4;
DE   AltName: Full=Renal carcinoma antigen NY-REN-53;
GN   Name=GCC2; Synonyms=KIAA0336, RANBP2L4;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0090161; P:Golgi ribbon formation; IMP:UniProtKB.
DR   GO; GO:0034499; P:late endosome to Golgi transport; IMP:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; IMP:UniProtKB.
DR   GO; GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IMP:UniProtKB.
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
DR   GO; GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.
DR   GO; GO:0071955; P:recycling endosome to Golgi transport; IMP:UniProtKB.
DR   GO; GO:0070861; P:regulation of protein exit from endoplasmic reticulum; IMP:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   GCDH_HUMAN              Reviewed;         438 AA.
AC   Q92947; A8K2Z2; O14719;
DE   RecName: Full=Glutaryl-CoA dehydrogenase, mitochondrial;
DE            Short=GCD;
DE            EC=1.3.8.6;
DE   Flags: Precursor;
GN   Name=GCDH;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:Ensembl.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0004361; F:glutaryl-CoA dehydrogenase activity; EXP:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019395; P:fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0046949; P:fatty-acyl-CoA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006568; P:tryptophan metabolic process; IEA:UniProtKB-UniPathway.
//
ID   GCFC2_HUMAN             Reviewed;         781 AA.
AC   P16383; A4UHQ8; O95032; Q53TY0; Q6P2F2;
DE   RecName: Full=GC-rich sequence DNA-binding factor 2;
DE   AltName: Full=GC-rich sequence DNA-binding factor;
DE   AltName: Full=Transcription factor 9;
DE            Short=TCF-9;
GN   Name=GCFC2; Synonyms=C2orf3, GCF, TCF9;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GCH1_HUMAN              Reviewed;         250 AA.
AC   P30793; Q6FHY7; Q9Y4I8;
DE   RecName: Full=GTP cyclohydrolase 1;
DE            EC=3.5.4.16;
DE   AltName: Full=GTP cyclohydrolase I;
DE            Short=GTP-CH-I;
GN   Name=GCH1; Synonyms=DYT5, GCH;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0050662; F:coenzyme binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003934; F:GTP cyclohydrolase I activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0035998; P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IMP:MGI.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0042559; P:pteridine-containing compound biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:UniProtKB.
DR   GO; GO:0014916; P:regulation of lung blood pressure; IEA:Ensembl.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0048265; P:response to pain; ISS:UniProtKB.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   GCKR_HUMAN              Reviewed;         625 AA.
AC   Q14397; A1L4C2; B4DPQ2; Q53RY6; Q99522;
DE   RecName: Full=Glucokinase regulatory protein;
DE            Short=GKRP;
DE            Short=Glucokinase regulator;
GN   Name=GCKR;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR   GO; GO:0070095; F:fructose-6-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0033132; P:negative regulation of glucokinase activity; IDA:UniProtKB.
DR   GO; GO:0033133; P:positive regulation of glucokinase activity; IEA:Ensembl.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; ISS:BHF-UCL.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0009750; P:response to fructose; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:BHF-UCL.
DR   GO; GO:0046415; P:urate metabolic process; IMP:BHF-UCL.
//
ID   GCM1_HUMAN              Reviewed;         436 AA.
AC   Q9NP62; Q4VAQ7; Q5T0X0; Q99468; Q9P1X3;
DE   RecName: Full=Chorion-specific transcription factor GCMa;
DE            Short=hGCMa;
DE   AltName: Full=GCM motif protein 1;
DE   AltName: Full=Glial cells missing homolog 1;
GN   Name=GCM1; Synonyms=GCMA;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0008134; F:transcription factor binding; IPI:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0060018; P:astrocyte fate commitment; IEA:Ensembl.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0060706; P:cell differentiation involved in embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0060143; P:positive regulation of syncytium formation by plasma membrane fusion; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GCM2_HUMAN              Reviewed;         506 AA.
AC   O75603; Q5THN5;
DE   RecName: Full=Chorion-specific transcription factor GCMb;
DE            Short=hGCMb;
DE   AltName: Full=GCM motif protein 2;
DE   AltName: Full=Glial cells missing homolog 2;
GN   Name=GCM2; Synonyms=GCMB;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0060017; P:parathyroid gland development; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GCN1L_HUMAN             Reviewed;        2671 AA.
AC   Q92616; A8KAY1; O95001; O95651; Q6P2S3; Q86X65; Q8N5I5; Q8WU80;
AC   Q99736; Q9UE60;
DE   RecName: Full=Translational activator GCN1;
DE            Short=HsGCN1;
DE   AltName: Full=GCN1-like protein 1;
GN   Name=GCN1L1; Synonyms=KIAA0219;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; NAS:GOC.
//
ID   GCNT1_HUMAN             Reviewed;         428 AA.
AC   Q02742; Q6DJZ4;
DE   RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase;
DE            EC=2.4.1.102;
DE   AltName: Full=Core 2-branching enzyme;
DE   AltName: Full=Core2-GlcNAc-transferase;
DE            Short=C2GNT;
DE            Short=Core 2 GNT;
GN   Name=GCNT1; Synonyms=NACGT2;
DR   GO; GO:0003829; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060352; P:cell adhesion molecule production; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0060993; P:kidney morphogenesis; IEA:Ensembl.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IMP:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0048729; P:tissue morphogenesis; IEA:Ensembl.
//
ID   GCNT3_HUMAN             Reviewed;         438 AA.
AC   O95395;
DE   RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3;
DE            EC=2.4.1.102;
DE            EC=2.4.1.150;
DE   AltName: Full=C2GnT-mucin type;
DE            Short=C2GnT-M;
DE            Short=hC2GnT-M;
DE   AltName: Full=Core 2/core 4 beta-1,6-N-acetylglucosaminyltransferase;
DE            Short=C2/4GnT;
GN   Name=GCNT3;
DR   GO; GO:0047225; F:acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; IEA:Ensembl.
DR   GO; GO:0003829; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008109; F:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0002426; P:immunoglobulin production in mucosal tissue; IEA:Ensembl.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0060993; P:kidney morphogenesis; IEA:Ensembl.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; TAS:ProtInc.
DR   GO; GO:0048729; P:tissue morphogenesis; IEA:Ensembl.
//
ID   GCNT4_HUMAN             Reviewed;         453 AA.
AC   Q9P109;
DE   RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4;
DE            EC=2.4.1.102;
DE   AltName: Full=Core 2-branching enzyme 3;
DE   AltName: Full=Core2-GlcNAc-transferase 3;
DE            Short=C2GnT3;
GN   Name=GCNT4;
DR   GO; GO:0003829; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008109; F:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0002121; P:inter-male aggressive behavior; IEA:Ensembl.
DR   GO; GO:0060993; P:kidney morphogenesis; IEA:Ensembl.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; TAS:ProtInc.
DR   GO; GO:0042403; P:thyroid hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0048729; P:tissue morphogenesis; IEA:Ensembl.
//
ID   GCNT6_HUMAN             Reviewed;         391 AA.
AC   Q5T4J0;
DE   RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 6;
DE            EC=2.4.1.-;
GN   Name=GCNT6;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GCNT7_HUMAN             Reviewed;         430 AA.
AC   Q6ZNI0; Q9HCV8;
DE   RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7;
DE            EC=2.4.1.-;
GN   Name=GCNT7; Synonyms=C20orf105;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GCOM2_HUMAN             Reviewed;         368 AA.
AC   Q9BZD3;
DE   RecName: Full=Putative GRINL1B complex locus protein 2;
DE   AltName: Full=Glutamate receptor-like protein 1B;
GN   Name=GCOM2; Synonyms=GRINL1B;
//
ID   GCP2_HUMAN              Reviewed;         902 AA.
AC   Q9BSJ2; B4DM18; B7ZKL8; F5H4E0; F5H4L0; O43632; Q5VWX7;
DE   RecName: Full=Gamma-tubulin complex component 2;
DE            Short=GCP-2;
DE            Short=hGCP2;
DE   AltName: Full=Gamma-ring complex protein 103 kDa;
DE            Short=h103p;
DE            Short=hGrip103;
DE   AltName: Full=Spindle pole body protein Spc97 homolog;
DE            Short=hSpc97;
GN   Name=TUBGCP2; Synonyms=GCP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   GCP3_HUMAN              Reviewed;         907 AA.
AC   Q96CW5; O43631; O60852; O60853; Q5T8L2; Q7Z4K1; Q96I79;
DE   RecName: Full=Gamma-tubulin complex component 3;
DE            Short=GCP-3;
DE            Short=hGCP3;
DE   AltName: Full=Gamma-ring complex protein 104 kDa;
DE            Short=h104p;
DE            Short=hGrip104;
DE   AltName: Full=Spindle pole body protein Spc98 homolog;
DE            Short=hSpc98;
GN   Name=TUBGCP3; Synonyms=GCP3;
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; NAS:UniProtKB.
//
ID   GCP4_HUMAN              Reviewed;         667 AA.
AC   Q9UGJ1; B3KNK6; Q969X3; Q9NVF0;
DE   RecName: Full=Gamma-tubulin complex component 4;
DE            Short=GCP-4;
DE            Short=hGCP4;
DE   AltName: Full=Gamma-ring complex protein 76 kDa;
DE            Short=h76p;
DE            Short=hGrip76;
GN   Name=TUBGCP4; Synonyms=76P, GCP4;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; NAS:ProtInc.
//
ID   GCP5_HUMAN              Reviewed;        1024 AA.
AC   Q96RT8; E9PB12; Q6IQ52; Q96PY8;
DE   RecName: Full=Gamma-tubulin complex component 5;
DE            Short=GCP-5;
GN   Name=TUBGCP5; Synonyms=GCP5, KIAA1899;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   GCP60_HUMAN             Reviewed;         528 AA.
AC   Q9H3P7; B2RB29; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H6U3;
DE   RecName: Full=Golgi resident protein GCP60;
DE   AltName: Full=Acyl-CoA-binding domain-containing protein 3;
DE   AltName: Full=Golgi complex-associated protein 1;
DE            Short=GOCAP1;
DE   AltName: Full=Golgi phosphoprotein 1;
DE            Short=GOLPH1;
DE   AltName: Full=PBR- and PKA-associated protein 7;
DE   AltName: Full=Peripheral benzodiazepine receptor-associated protein PAP7;
GN   Name=ACBD3; Synonyms=GCP60, GOCAP1, GOLPH1;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   GCP6_HUMAN              Reviewed;        1819 AA.
AC   Q96RT7; Q5JZ80; Q6PJ40; Q86YE9; Q9BY91; Q9UGX3; Q9UGX4;
DE   RecName: Full=Gamma-tubulin complex component 6;
DE            Short=GCP-6;
GN   Name=TUBGCP6; Synonyms=GCP6, KIAA1669;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   GCR_HUMAN               Reviewed;         777 AA.
AC   P04150; A0ZXF9; B0LPG8; D3DQF4; P04151; Q53EP5; Q6N0A4;
DE   RecName: Full=Glucocorticoid receptor;
DE            Short=GR;
DE   AltName: Full=Nuclear receptor subfamily 3 group C member 1;
GN   Name=NR3C1; Synonyms=GRL;
DR   GuidetoPHARMACOLOGY; 625; -.
DR   GO; GO:0004883; F:glucocorticoid receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008211; P:glucocorticoid metabolic process; IEA:Ensembl.
DR   GO; GO:0060603; P:mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0031946; P:regulation of glucocorticoid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   GCSAM_HUMAN             Reviewed;         178 AA.
AC   Q8N6F7; C9JD17; C9JUG6;
DE   RecName: Full=Germinal center-associated signaling and motility protein;
DE   AltName: Full=Germinal center B-cell-expressed transcript 2 protein;
DE   AltName: Full=Germinal center-associated lymphoma protein;
DE            Short=hGAL;
GN   Name=GCSAM; Synonyms=GAL, GCET2;
DR   GO; GO:0003779; F:actin binding; IPI:UniProtKB.
DR   GO; GO:0045159; F:myosin II binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:2000402; P:negative regulation of lymphocyte migration; IMP:UniProtKB.
DR   GO; GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:UniProtKB.
//
ID   GCSH_HUMAN              Reviewed;         173 AA.
AC   P23434; Q9H1E9;
DE   RecName: Full=Glycine cleavage system H protein, mitochondrial;
DE   AltName: Full=Lipoic acid-containing protein;
DE   Flags: Precursor;
GN   Name=GCSH;
DR   GO; GO:0004047; F:aminomethyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006546; P:glycine catabolic process; TAS:ProtInc.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:Ensembl.
DR   GO; GO:0032259; P:methylation; TAS:GOC.
//
ID   GCSP_HUMAN              Reviewed;        1020 AA.
AC   P23378; Q2M2F8;
DE   RecName: Full=Glycine dehydrogenase (decarboxylating), mitochondrial;
DE            EC=1.4.4.2;
DE   AltName: Full=Glycine cleavage system P protein;
DE   AltName: Full=Glycine decarboxylase;
DE   AltName: Full=Glycine dehydrogenase (aminomethyl-transferring);
DE   Flags: Precursor;
GN   Name=GLDC; Synonyms=GCSP;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004375; F:glycine dehydrogenase (decarboxylating) activity; TAS:ProtInc.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006546; P:glycine catabolic process; TAS:ProtInc.
//
ID   GCST_HUMAN              Reviewed;         403 AA.
AC   P48728; A8K3I5; B4DE61; B4DJQ0; E9PBG1; Q96IG6;
DE   RecName: Full=Aminomethyltransferase, mitochondrial;
DE            EC=2.1.2.10;
DE   AltName: Full=Glycine cleavage system T protein;
DE            Short=GCVT;
DE   Flags: Precursor;
GN   Name=AMT; Synonyms=GCST;
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006546; P:glycine catabolic process; TAS:ProtInc.
//
ID   GCYA2_HUMAN             Reviewed;         732 AA.
AC   P33402; A1L4C4; B7ZLT5;
DE   RecName: Full=Guanylate cyclase soluble subunit alpha-2;
DE            Short=GCS-alpha-2;
DE            EC=4.6.1.2;
GN   Name=GUCY1A2; Synonyms=GUC1A2, GUCSA2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GCYA3_HUMAN             Reviewed;         690 AA.
AC   Q02108; D3DP19; D6RDW3; O43843; Q8TAH3;
DE   RecName: Full=Guanylate cyclase soluble subunit alpha-3;
DE            Short=GCS-alpha-3;
DE            EC=4.6.1.2;
DE   AltName: Full=GCS-alpha-1;
DE   AltName: Full=Soluble guanylate cyclase large subunit;
GN   Name=GUCY1A3; Synonyms=GUC1A3, GUCSA3, GUCY1A1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0060087; P:relaxation of vascular smooth muscle; IEA:Ensembl.
DR   GO; GO:0052565; P:response to defense-related host nitric oxide production; IEA:Ensembl.
//
ID   GCYB1_HUMAN             Reviewed;         619 AA.
AC   Q02153; B7Z426; Q86WY5;
DE   RecName: Full=Guanylate cyclase soluble subunit beta-1;
DE            Short=GCS-beta-1;
DE            EC=4.6.1.2;
DE   AltName: Full=Guanylate cyclase soluble subunit beta-3;
DE            Short=GCS-beta-3;
DE   AltName: Full=Soluble guanylate cyclase small subunit;
GN   Name=GUCY1B3; Synonyms=GUC1B3, GUCSB3, GUCY1B1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; TAS:ProtInc.
//
ID   GCYB2_HUMAN             Reviewed;         617 AA.
AC   O75343; Q9NZ64;
DE   RecName: Full=Guanylate cyclase soluble subunit beta-2;
DE            Short=GCS-beta-2;
DE            EC=4.6.1.2;
GN   Name=GUCY1B2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   GD1L1_HUMAN             Reviewed;         367 AA.
AC   Q96MZ0; B7Z621; Q5TE60; Q68CW7; Q9BQJ7; Q9BQV4; Q9BWJ4; Q9H3Y2;
AC   Q9H4G5;
DE   RecName: Full=Ganglioside-induced differentiation-associated protein 1-like 1;
DE            Short=GDAP1-L1;
GN   Name=GDAP1L1;
//
ID   GDAP1_HUMAN             Reviewed;         358 AA.
AC   Q8TB36; A8K957; E7FJF3; E7FJF4;
DE   RecName: Full=Ganglioside-induced differentiation-associated protein 1;
DE            Short=GDAP1;
GN   Name=GDAP1;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0000266; P:mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IMP:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   GDAP2_HUMAN             Reviewed;         497 AA.
AC   Q9NXN4; Q96DZ0;
DE   RecName: Full=Ganglioside-induced differentiation-associated protein 2;
GN   Name=GDAP2;
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   GDC_HUMAN               Reviewed;         332 AA.
AC   P16260; Q8N2U1;
DE   RecName: Full=Graves disease carrier protein;
DE            Short=GDC;
DE   AltName: Full=Graves disease autoantigen;
DE            Short=GDA;
DE   AltName: Full=Mitochondrial solute carrier protein homolog;
DE   AltName: Full=Solute carrier family 25 member 16;
GN   Name=SLC25A16; Synonyms=GDA;
DR   GO; GO:0015297; F:antiporter activity; NAS:UniProtKB.
DR   GO; GO:0009108; P:coenzyme biosynthetic process; TAS:Reactome.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   GDE1_HUMAN              Reviewed;         331 AA.
AC   Q9NZC3; O43334; Q6PKF7; Q7KYR4;
DE   RecName: Full=Glycerophosphodiester phosphodiesterase 1;
DE            EC=3.1.4.44;
DE   AltName: Full=Membrane-interacting protein of RGS16;
DE   AltName: Full=RGS16-interacting membrane protein;
GN   Name=GDE1; Synonyms=MIR16;
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; TAS:UniProtKB.
DR   GO; GO:0047395; F:glycerophosphoinositol glycerophosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:UniProtKB.
//
ID   GDE_HUMAN               Reviewed;        1532 AA.
AC   P35573; A6NCX7; A6NEK2; D3DT51; P78354; P78544; Q59H92; Q6AZ90;
AC   Q9UF08;
DE   RecName: Full=Glycogen debranching enzyme;
DE   AltName: Full=Glycogen debrancher;
DE   Includes:
DE     RecName: Full=4-alpha-glucanotransferase;
DE              EC=2.4.1.25;
DE     AltName: Full=Oligo-1,4-1,4-glucantransferase;
DE   Includes:
DE     RecName: Full=Amylo-alpha-1,6-glucosidase;
DE              Short=Amylo-1,6-glucosidase;
DE              EC=3.2.1.33;
DE     AltName: Full=Dextrin 6-alpha-D-glucosidase;
GN   Name=AGL; Synonyms=GDE;
DR   GO; GO:0004134; F:4-alpha-glucanotransferase activity; IBA:RefGenome.
DR   GO; GO:0004135; F:amylo-alpha-1,6-glucosidase activity; IBA:RefGenome.
DR   GO; GO:0004133; F:glycogen debranching enzyme activity; TAS:ProtInc.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0005980; P:glycogen catabolic process; IBA:RefGenome.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GDF11_HUMAN             Reviewed;         407 AA.
AC   O95390; Q9UID1; Q9UID2;
DE   RecName: Full=Growth/differentiation factor 11;
DE            Short=GDF-11;
DE   AltName: Full=Bone morphogenetic protein 11;
DE            Short=BMP-11;
DE   Flags: Precursor;
GN   Name=GDF11; Synonyms=BMP11;
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0007498; P:mesoderm development; TAS:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:UniProtKB.
DR   GO; GO:0021512; P:spinal cord anterior/posterior patterning; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   GDF1_HUMAN              Reviewed;         372 AA.
AC   P27539; O43344;
DE   RecName: Full=Embryonic growth/differentiation factor 1;
DE            Short=GDF-1;
DE   Flags: Precursor;
GN   Name=GDF1;
DR   GO; GO:0040007; P:growth; IEA:InterPro.
//
ID   GDF15_HUMAN             Reviewed;         308 AA.
AC   Q99988; O14629; P78360; Q9BWA0; Q9NRT0;
DE   RecName: Full=Growth/differentiation factor 15;
DE            Short=GDF-15;
DE   AltName: Full=Macrophage inhibitory cytokine 1;
DE            Short=MIC-1;
DE   AltName: Full=NSAID-activated gene 1 protein;
DE            Short=NAG-1;
DE   AltName: Full=NSAID-regulated gene 1 protein;
DE            Short=NRG-1;
DE   AltName: Full=Placental TGF-beta;
DE   AltName: Full=Placental bone morphogenetic protein;
DE   AltName: Full=Prostate differentiation factor;
DE   Flags: Precursor;
GN   Name=GDF15; Synonyms=MIC1, PDF, PLAB, PTGFB;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   GDF2_HUMAN              Reviewed;         429 AA.
AC   Q9UK05; Q5VSQ9; Q9Y571;
DE   RecName: Full=Growth/differentiation factor 2;
DE            Short=GDF-2;
DE   AltName: Full=Bone morphogenetic protein 9;
DE            Short=BMP-9;
DE   Flags: Precursor;
GN   Name=GDF2; Synonyms=BMP9;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IMP:UniProtKB.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IDA:DFLAT.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; TAS:DFLAT.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:DFLAT.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; TAS:DFLAT.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; TAS:DFLAT.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0008156; P:negative regulation of DNA replication; TAS:DFLAT.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:DFLAT.
DR   GO; GO:0001503; P:ossification; TAS:DFLAT.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; IDA:DFLAT.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:DFLAT.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   GDF3_HUMAN              Reviewed;         364 AA.
AC   Q9NR23; Q8NEJ4;
DE   RecName: Full=Growth/differentiation factor 3;
DE            Short=GDF-3;
DE   Flags: Precursor;
GN   Name=GDF3; ORFNames=UNQ222/PRO248;
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProt.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
DR   GO; GO:0048859; P:formation of anatomical boundary; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProt.
DR   GO; GO:0045605; P:negative regulation of epidermal cell differentiation; IDA:UniProt.
DR   GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; IEA:Ensembl.
DR   GO; GO:0010453; P:regulation of cell fate commitment; IDA:UniProt.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
//
ID   GDF5O_HUMAN             Reviewed;         250 AA.
AC   Q5U4N7; A6PVI8;
DE   RecName: Full=Protein GDF5OS, mitochondrial;
DE   AltName: Full=Growth/differentiation factor 5 opposite strand transcript protein;
DE   Flags: Precursor;
GN   Name=GDF5OS;
//
ID   GDF5_HUMAN              Reviewed;         501 AA.
AC   P43026; E1P5Q2; Q96SB1;
DE   RecName: Full=Growth/differentiation factor 5;
DE            Short=GDF-5;
DE   AltName: Full=Bone morphogenetic protein 14;
DE            Short=BMP-14;
DE   AltName: Full=Cartilage-derived morphogenetic protein 1;
DE            Short=CDMP-1;
DE   AltName: Full=Lipopolysaccharide-associated protein 4;
DE            Short=LAP-4;
DE            Short=LPS-associated protein 4;
DE   AltName: Full=Radotermin;
DE   Flags: Precursor;
GN   Name=GDF5; Synonyms=BMP14, CDMP1;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0035136; P:forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   GDF6_HUMAN              Reviewed;         455 AA.
AC   Q6KF10; Q6PI58;
DE   RecName: Full=Growth/differentiation factor 6;
DE            Short=GDF-6;
DE   AltName: Full=Bone morphogenetic protein 13;
DE            Short=BMP-13;
DE   AltName: Full=Growth/differentiation factor 16;
DE   Flags: Precursor;
GN   Name=GDF6; Synonyms=BMP13, GDF16;
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:1990009; P:retinal cell apoptotic process; ISS:UniProtKB.
//
ID   GDF7_HUMAN              Reviewed;         450 AA.
AC   Q7Z4P5;
DE   RecName: Full=Growth/differentiation factor 7;
DE            Short=GDF-7;
DE   Flags: Precursor;
GN   Name=GDF7;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0022612; P:gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0060571; P:morphogenesis of an epithelial fold; IEA:Ensembl.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:2001051; P:positive regulation of tendon cell differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0048608; P:reproductive structure development; IEA:Ensembl.
DR   GO; GO:0021509; P:roof plate formation; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
//
ID   GDF8_HUMAN              Reviewed;         375 AA.
AC   O14793; A1C2J7; A1C2K0; Q6B0H2;
DE   RecName: Full=Growth/differentiation factor 8;
DE            Short=GDF-8;
DE   AltName: Full=Myostatin;
DE   Flags: Precursor;
GN   Name=MSTN; Synonyms=GDF8;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:HGNC.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0014741; P:negative regulation of muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:0048632; P:negative regulation of skeletal muscle tissue growth; IEA:Ensembl.
DR   GO; GO:0022602; P:ovulation cycle process; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0014732; P:skeletal muscle atrophy; IEA:Ensembl.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   GDF9_HUMAN              Reviewed;         454 AA.
AC   O60383; Q4VAW5;
DE   RecName: Full=Growth/differentiation factor 9;
DE            Short=GDF-9;
DE   Flags: Precursor;
GN   Name=GDF9;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0001555; P:oocyte growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000870; P:regulation of progesterone secretion; IDA:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   GDIA_HUMAN              Reviewed;         447 AA.
AC   P31150; P50394; Q6FG50; Q7Z2G6; Q7Z2G9; Q7Z2H5; Q7Z2I6;
DE   RecName: Full=Rab GDP dissociation inhibitor alpha;
DE            Short=Rab GDI alpha;
DE   AltName: Full=Guanosine diphosphate dissociation inhibitor 1;
DE            Short=GDI-1;
DE   AltName: Full=Oligophrenin-2;
DE   AltName: Full=Protein XAP-4;
GN   Name=GDI1; Synonyms=GDIL, OPHN2, RABGDIA, XAP4;
DR   GO; GO:0005092; F:GDP-dissociation inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0090315; P:negative regulation of protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0032482; P:Rab protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   GDIB_HUMAN              Reviewed;         445 AA.
AC   P50395; O43928; Q5SX88; Q9UQM6;
DE   RecName: Full=Rab GDP dissociation inhibitor beta;
DE            Short=Rab GDI beta;
DE   AltName: Full=Guanosine diphosphate dissociation inhibitor 2;
DE            Short=GDI-2;
GN   Name=GDI2; Synonyms=RABGDIB;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   GDIR1_HUMAN             Reviewed;         204 AA.
AC   P52565; A8MXW0; B2R5X1; B4DDD3; B4DUV9; Q6IBM5;
DE   RecName: Full=Rho GDP-dissociation inhibitor 1;
DE            Short=Rho GDI 1;
DE   AltName: Full=Rho-GDI alpha;
GN   Name=ARHGDIA; Synonyms=GDIA1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005094; F:Rho GDP-dissociation inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   GDIR2_HUMAN             Reviewed;         201 AA.
AC   P52566; B5BU79;
DE   RecName: Full=Rho GDP-dissociation inhibitor 2;
DE            Short=Rho GDI 2;
DE   AltName: Full=Ly-GDI;
DE   AltName: Full=Rho-GDI beta;
GN   Name=ARHGDIB; Synonyms=GDIA2, GDID4, RAP1GN1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005094; F:Rho GDP-dissociation inhibitor activity; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   GDIR3_HUMAN             Reviewed;         225 AA.
AC   Q99819; Q4TT69; Q96S29;
DE   RecName: Full=Rho GDP-dissociation inhibitor 3;
DE            Short=Rho GDI 3;
DE   AltName: Full=Rho-GDI gamma;
GN   Name=ARHGDIG;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005094; F:Rho GDP-dissociation inhibitor activity; TAS:ProtInc.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   GDNF_HUMAN              Reviewed;         211 AA.
AC   P39905; B7WPK7; O95448; O95449; O95986; Q6FH33; Q96L44; Q9UD32;
AC   Q9UD33; Q9UMV2; Q9UP67; Q9UP97;
DE   RecName: Full=Glial cell line-derived neurotrophic factor;
DE            Short=hGDNF;
DE   AltName: Full=Astrocyte-derived trophic factor;
DE            Short=ATF;
DE   Flags: Precursor;
GN   Name=GDNF;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008344; P:adult locomotory behavior; TAS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048484; P:enteric nervous system development; ISS:UniProtKB.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; ISS:UniProtKB.
DR   GO; GO:0048255; P:mRNA stabilization; IDA:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001755; P:neural crest cell migration; IDA:MGI.
DR   GO; GO:0031175; P:neuron projection development; IDA:MGI.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; ISS:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IDA:UniProtKB.
DR   GO; GO:0033603; P:positive regulation of dopamine secretion; TAS:BHF-UCL.
DR   GO; GO:0072108; P:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0032770; P:positive regulation of monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0072107; P:positive regulation of ureteric bud formation; IDA:UniProtKB.
DR   GO; GO:0021784; P:postganglionic parasympathetic nervous system development; ISS:UniProtKB.
DR   GO; GO:0001941; P:postsynaptic membrane organization; IEA:Ensembl.
DR   GO; GO:0051584; P:regulation of dopamine uptake involved in synaptic transmission; IDA:UniProtKB.
DR   GO; GO:0060688; P:regulation of morphogenesis of a branching structure; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
DR   GO; GO:0060676; P:ureteric bud formation; IEA:Ensembl.
//
ID   GDN_HUMAN               Reviewed;         398 AA.
AC   P07093; B2R6A4; B4DIF2; Q53S15; Q5D0C4;
DE   RecName: Full=Glia-derived nexin;
DE            Short=GDN;
DE   AltName: Full=Peptidase inhibitor 7;
DE            Short=PI-7;
DE   AltName: Full=Protease nexin 1;
DE            Short=PN-1;
DE   AltName: Full=Protease nexin I;
DE   AltName: Full=Serpin E2;
DE   Flags: Precursor;
GN   Name=SERPINE2; Synonyms=PI7, PN1;
DR   GO; GO:0005539; F:glycosaminoglycan binding; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0021683; P:cerebellar granular layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0050974; P:detection of mechanical stimulus involved in sensory perception; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0042628; P:mating plug formation; IEA:Ensembl.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0010757; P:negative regulation of plasminogen activation; IMP:BHF-UCL.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IEA:Ensembl.
DR   GO; GO:0090331; P:negative regulation of platelet aggregation; ISS:BHF-UCL.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0010955; P:negative regulation of protein processing; IC:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0010766; P:negative regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0030334; P:regulation of cell migration; NAS:UniProtKB.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0048505; P:regulation of timing of cell differentiation; IEA:Ensembl.
DR   GO; GO:0032940; P:secretion by cell; IEA:Ensembl.
DR   GO; GO:0033363; P:secretory granule organization; IEA:Ensembl.
DR   GO; GO:0061108; P:seminal vesicle epithelium development; IEA:Ensembl.
//
ID   GDPD1_HUMAN             Reviewed;         314 AA.
AC   Q8N9F7; A8W735; Q56VR1; Q8N4E3;
DE   RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 1;
DE            EC=3.1.-.-;
DE   AltName: Full=Glycerophosphodiester phosphodiesterase 4;
GN   Name=GDPD1; Synonyms=GDE4;
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   GDPD2_HUMAN             Reviewed;         539 AA.
AC   Q9HCC8; B4DRH4; B4DVC9; Q9NXJ6;
DE   RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2;
DE            EC=3.1.4.43;
DE   AltName: Full=Glycerophosphodiester phosphodiesterase 3;
DE   AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2;
DE   AltName: Full=Osteoblast differentiation promoting factor;
GN   Name=GDPD2; Synonyms=GDE3, OBDPF; ORFNames=UNQ1935/PRO4418;
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0047394; F:glycerophosphoinositol inositolphosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   GDPD3_HUMAN             Reviewed;         318 AA.
AC   Q7L5L3; Q9H652;
DE   RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 3;
DE            EC=3.1.-.-;
GN   Name=GDPD3;
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   GDPD4_HUMAN             Reviewed;         623 AA.
AC   Q6W3E5; Q7Z5B0;
DE   RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 4;
DE            EC=3.1.-.-;
DE   AltName: Full=Glycerophosphodiester phosphodiesterase 6;
DE   AltName: Full=UgpQ;
GN   Name=GDPD4; Synonyms=GDE6, UGPQ;
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   GDPD5_HUMAN             Reviewed;         605 AA.
AC   Q8WTR4; Q49AQ5; Q6UX76; Q7Z4S0; Q8N781; Q8NCB7; Q8TB77;
DE   RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5;
DE            EC=3.1.-.-;
DE   AltName: Full=Glycerophosphodiester phosphodiesterase 2;
GN   Name=GDPD5; Synonyms=GDE2; ORFNames=PP6037, PP9363, UNQ1850/PRO3580;
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048505; P:regulation of timing of cell differentiation; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
//
ID   GDPP1_HUMAN             Reviewed;         385 AA.
AC   Q6ZNW5;
DE   RecName: Full=GDP-D-glucose phosphorylase 1;
DE            EC=2.7.7.78;
GN   Name=GDPGP1; Synonyms=C15orf58;
DR   GO; GO:0080048; F:GDP-D-glucose phosphorylase activity; IDA:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:UniProtKB.
//
ID   GDS1_HUMAN              Reviewed;         607 AA.
AC   P52306; E9PH06; G5E9P9; Q499L7; Q4KMV2; Q4QQI8; Q9BUW9; Q9BUX6;
AC   Q9NYM2; Q9NZA8;
DE   RecName: Full=Rap1 GTPase-GDP dissociation stimulator 1;
DE   AltName: Full=Exchange factor smgGDS;
DE   AltName: Full=SMG GDS protein;
DE   AltName: Full=SMG P21 stimulatory GDP/GTP exchange protein;
GN   Name=RAP1GDS1;
DR   GO; GO:0005096; F:GTPase activator activity; NAS:UniProtKB.
DR   GO; GO:0031034; P:myosin filament assembly; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0014829; P:vascular smooth muscle contraction; IEA:Ensembl.
//
ID   GELS_HUMAN              Reviewed;         782 AA.
AC   P06396; A2A418; A8MUD1; A8MYN7; B7Z373; B7Z5V1; F5H1A8; Q5T0I2;
AC   Q8WVV7;
DE   RecName: Full=Gelsolin;
DE   AltName: Full=AGEL;
DE   AltName: Full=Actin-depolymerizing factor;
DE            Short=ADF;
DE   AltName: Full=Brevin;
DE   Flags: Precursor;
GN   Name=GSN;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030041; P:actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0051014; P:actin filament severing; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0051016; P:barbed-end actin filament capping; TAS:ProtInc.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:Ensembl.
//
ID   GEMC1_HUMAN             Reviewed;         334 AA.
AC   A6NCL1;
DE   RecName: Full=Geminin coiled-coil domain-containing protein 1;
GN   Name=GMNC; Synonyms=GEMC1;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
//
ID   GEMI2_HUMAN             Reviewed;         280 AA.
AC   O14893; B2R9W8; Q2M3B3; Q9H4F5; Q9NS77; Q9NS78; Q9NS79;
DE   RecName: Full=Gem-associated protein 2;
DE            Short=Gemin-2;
DE   AltName: Full=Component of gems 2;
DE   AltName: Full=Survival of motor neuron protein-interacting protein 1;
DE            Short=SMN-interacting protein 1;
GN   Name=GEMIN2; Synonyms=SIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; TAS:ProtInc.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   GEMI4_HUMAN             Reviewed;        1058 AA.
AC   P57678; Q9NZS7; Q9UG32; Q9Y4Q2;
DE   RecName: Full=Gem-associated protein 4;
DE            Short=Gemin-4;
DE   AltName: Full=Component of gems 4;
DE   AltName: Full=p97;
GN   Name=GEMIN4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   GEMI5_HUMAN             Reviewed;        1508 AA.
AC   Q8TEQ6; Q14CV0; Q8WWV4; Q969W4; Q9H9K3; Q9UFI5;
DE   RecName: Full=Gem-associated protein 5;
DE            Short=Gemin5;
GN   Name=GEMIN5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017069; F:snRNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   GEMI6_HUMAN             Reviewed;         167 AA.
AC   Q8WXD5; B2RDP8; Q53SI5; Q8WVB4; Q9H5G6;
DE   RecName: Full=Gem-associated protein 6;
DE            Short=Gemin-6;
DE   AltName: Full=SIP2;
GN   Name=GEMIN6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IEA:InterPro.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   GEMI7_HUMAN             Reviewed;         131 AA.
AC   Q9H840; Q6IA34;
DE   RecName: Full=Gem-associated protein 7;
DE            Short=Gemin-7;
DE   AltName: Full=SIP3;
GN   Name=GEMIN7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   GEMI8_HUMAN             Reviewed;         242 AA.
AC   Q9NWZ8; C4AMC4; Q2LJ66; Q6ZV27;
DE   RecName: Full=Gem-associated protein 8;
DE            Short=Gemin-8;
DE   AltName: Full=Protein FAM51A1;
GN   Name=GEMIN8; Synonyms=FAM51A1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   GEMI_HUMAN              Reviewed;         209 AA.
AC   O75496; B3KMM8; Q9H1Z1;
DE   RecName: Full=Geminin;
GN   Name=GMNN;
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
//
ID   GEM_HUMAN               Reviewed;         296 AA.
AC   P55040; B2RA31;
DE   RecName: Full=GTP-binding protein GEM;
DE   AltName: Full=GTP-binding mitogen-induced T-cell protein;
DE   AltName: Full=RAS-like protein KIR;
GN   Name=GEM; Synonyms=KIR;
DR   GO; GO:0019003; F:GDP binding; IDA:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0003924; F:GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0051276; P:chromosome organization; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0051310; P:metaphase plate congression; IMP:UniProt.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   GEN_HUMAN               Reviewed;         908 AA.
AC   Q17RS7; Q17RS9; Q6ZN37;
DE   RecName: Full=Flap endonuclease GEN homolog 1;
DE            EC=3.1.-.-;
GN   Name=GEN1;
DR   GO; GO:0008821; F:crossover junction endodeoxyribonuclease activity; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IMP:GOC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0071140; P:resolution of mitotic recombination intermediates; IMP:UniProtKB.
DR   GO; GO:0071139; P:resolution of recombination intermediates; IMP:UniProtKB.
//
ID   GEPH_HUMAN              Reviewed;         736 AA.
AC   Q9NQX3; Q9H4E9; Q9P2G2;
DE   RecName: Full=Gephyrin;
DE   Includes:
DE     RecName: Full=Molybdopterin adenylyltransferase;
DE              Short=MPT adenylyltransferase;
DE              EC=2.7.7.75;
DE     AltName: Full=Domain G;
DE   Includes:
DE     RecName: Full=Molybdopterin molybdenumtransferase;
DE              Short=MPT Mo-transferase;
DE              EC=2.10.1.1;
DE     AltName: Full=Domain E;
GN   Name=GPHN; Synonyms=GPH, KIAA1385;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061598; F:molybdopterin adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0061599; F:molybdopterin molybdotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016740; F:transferase activity; TAS:Reactome.
DR   GO; GO:0007529; P:establishment of synaptic specificity at neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   GET4_HUMAN              Reviewed;         327 AA.
AC   Q7L5D6; A4D2Q1; B3KNC7; Q9UFC9; Q9Y309;
DE   RecName: Full=Golgi to ER traffic protein 4 homolog;
DE   AltName: Full=Conserved edge-expressed protein;
DE   AltName: Full=Transmembrane domain recognition complex 35 kDa subunit;
DE            Short=TRC35;
GN   Name=GET4; Synonyms=C7orf20, CEE, TRC35; ORFNames=CGI-20;
DR   GO; GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   GFAP_HUMAN              Reviewed;         432 AA.
AC   P14136; B2RD44; D3DX59; E9PAX3; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6;
AC   Q7Z5J7; Q96KS4; Q96P18; Q9UFD0;
DE   RecName: Full=Glial fibrillary acidic protein;
DE            Short=GFAP;
GN   Name=GFAP;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0014002; P:astrocyte development; IEA:Ensembl.
DR   GO; GO:0060020; P:Bergmann glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0031102; P:neuron projection regeneration; IEA:Ensembl.
DR   GO; GO:0010625; P:positive regulation of Schwann cell proliferation; IEA:Ensembl.
DR   GO; GO:0051580; P:regulation of neurotransmitter uptake; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
//
ID   GFI1B_HUMAN             Reviewed;         330 AA.
AC   Q5VTD9; O95270; Q5VTD8; Q6FHZ2; Q6T888;
DE   RecName: Full=Zinc finger protein Gfi-1b;
DE   AltName: Full=Growth factor independent protein 1B;
DE   AltName: Full=Potential regulator of CDKN1A translocated in CML;
GN   Name=GFI1B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   GFI1_HUMAN              Reviewed;         422 AA.
AC   Q99684; Q8N564;
DE   RecName: Full=Zinc finger protein Gfi-1;
DE   AltName: Full=Growth factor independent protein 1;
DE   AltName: Full=Zinc finger protein 163;
GN   Name=GFI1; Synonyms=ZNF163;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProt.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007638; P:mechanosensory behavior; IEA:Ensembl.
DR   GO; GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0009996; P:negative regulation of cell fate specification; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0042660; P:positive regulation of cell fate specification; IEA:Ensembl.
DR   GO; GO:0070105; P:positive regulation of interleukin-6-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0034121; P:regulation of toll-like receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:ProtInc.
//
ID   GFOD1_HUMAN             Reviewed;         390 AA.
AC   Q9NXC2; A8E4L6; Q5T058; Q96JD4; Q9H5K2;
DE   RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=GFOD1; Synonyms=C6orf114;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   GFOD2_HUMAN             Reviewed;         385 AA.
AC   Q3B7J2; Q69YL9; Q6UXX6; Q7L648; Q8TE86; Q9BQ07;
DE   RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 2;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=GFOD2; ORFNames=UNQ9430/PRO34691;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
//
ID   GFPT1_HUMAN             Reviewed;         699 AA.
AC   Q06210; Q53QE6; Q9BXF8;
DE   RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1;
DE            EC=2.6.1.16;
DE   AltName: Full=D-fructose-6-phosphate amidotransferase 1;
DE   AltName: Full=Glutamine:fructose-6-phosphate amidotransferase 1;
DE            Short=GFAT 1;
DE            Short=GFAT1;
DE   AltName: Full=Hexosephosphate aminotransferase 1;
GN   Name=GFPT1; Synonyms=GFAT, GFPT;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:ProtInc.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; TAS:ProtInc.
DR   GO; GO:0006042; P:glucosamine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0009744; P:response to sucrose; IEA:Ensembl.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; TAS:Reactome.
//
ID   GFPT2_HUMAN             Reviewed;         682 AA.
AC   O94808; Q53XM2; Q9BWS4;
DE   RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2;
DE            EC=2.6.1.16;
DE   AltName: Full=D-fructose-6-phosphate amidotransferase 2;
DE   AltName: Full=Glutamine:fructose-6-phosphate amidotransferase 2;
DE            Short=GFAT 2;
DE            Short=GFAT2;
DE   AltName: Full=Hexosephosphate aminotransferase 2;
GN   Name=GFPT2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; TAS:ProtInc.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:ProtInc.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; TAS:ProtInc.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; TAS:Reactome.
//
ID   GFRA1_HUMAN             Reviewed;         465 AA.
AC   P56159; A8KA21; O15507; O43912;
DE   RecName: Full=GDNF family receptor alpha-1;
DE            Short=GDNF receptor alpha-1;
DE            Short=GDNFR-alpha-1;
DE            Short=GFR-alpha-1;
DE   AltName: Full=RET ligand 1;
DE   AltName: Full=TGF-beta-related neurotrophic factor receptor 1;
DE   Flags: Precursor;
GN   Name=GFRA1; Synonyms=GDNFRA, RETL1, TRNR1;
DR   GuidetoPHARMACOLOGY; 1743; -.
DR   GO; GO:0016167; F:glial cell-derived neurotrophic factor receptor activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0035860; P:glial cell-derived neurotrophic factor receptor signaling pathway; TAS:GOC.
//
ID   GFRA2_HUMAN             Reviewed;         464 AA.
AC   O00451; E9PD47; O15316; O15328; Q58J92; Q6GTR9; Q7Z5C2;
DE   RecName: Full=GDNF family receptor alpha-2;
DE            Short=GDNF receptor alpha-2;
DE            Short=GDNFR-alpha-2;
DE            Short=GFR-alpha-2;
DE   AltName: Full=GDNF receptor beta;
DE            Short=GDNFR-beta;
DE   AltName: Full=Neurturin receptor alpha;
DE            Short=NRTNR-alpha;
DE            Short=NTNR-alpha;
DE   AltName: Full=RET ligand 2;
DE   AltName: Full=TGF-beta-related neurotrophic factor receptor 2;
DE   Flags: Precursor;
GN   Name=GFRA2; Synonyms=GDNFRB, RETL2, TRNR2;
DR   GO; GO:0016167; F:glial cell-derived neurotrophic factor receptor activity; TAS:ProtInc.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   GFRA3_HUMAN             Reviewed;         400 AA.
AC   O60609; B2RA36; B4DMY9; Q6UW20; Q8IUZ2;
DE   RecName: Full=GDNF family receptor alpha-3;
DE            Short=GDNF receptor alpha-3;
DE            Short=GDNFR-alpha-3;
DE            Short=GFR-alpha-3;
DE   Flags: Precursor;
GN   Name=GFRA3; ORFNames=UNQ339/PRO538/PRO3664;
DR   GO; GO:0008046; F:axon guidance receptor activity; IEA:Ensembl.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Ensembl.
//
ID   GFRA4_HUMAN             Reviewed;         299 AA.
AC   Q9GZZ7; Q5JT74; Q9H191; Q9H192;
DE   RecName: Full=GDNF family receptor alpha-4;
DE            Short=GDNF receptor alpha-4;
DE            Short=GDNFR-alpha-4;
DE            Short=GFR-alpha-4;
DE   AltName: Full=Persephin receptor;
DE   Flags: Precursor;
GN   Name=GFRA4;
DR   GO; GO:0016167; F:glial cell-derived neurotrophic factor receptor activity; IEA:Ensembl.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
//
ID   GFRAL_HUMAN             Reviewed;         394 AA.
AC   Q6UXV0; Q5VTF6;
DE   RecName: Full=GDNF family receptor alpha-like;
DE   Flags: Precursor;
GN   Name=GFRAL; Synonyms=C6orf144; ORFNames=UNQ9356/PRO34128;
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0031098; P:stress-activated protein kinase signaling cascade; IEA:Ensembl.
//
ID   GFRP_HUMAN              Reviewed;          84 AA.
AC   P30047; B2R4L6; Q2M1Q2; Q99749;
DE   RecName: Full=GTP cyclohydrolase 1 feedback regulatory protein;
DE            Short=GFRP;
DE   AltName: Full=GTP cyclohydrolase I feedback regulatory protein;
DE   AltName: Full=p35;
GN   Name=GCHFR; Synonyms=GFRP;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009890; P:negative regulation of biosynthetic process; IEA:InterPro.
DR   GO; GO:0043105; P:negative regulation of GTP cyclohydrolase I activity; IEA:Ensembl.
DR   GO; GO:0042133; P:neurotransmitter metabolic process; TAS:ProtInc.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GFY_HUMAN               Reviewed;         518 AA.
AC   I3L273;
DE   RecName: Full=Golgi-associated olfactory signaling regulator;
DE   AltName: Full=Protein Goofy;
DE   Flags: Precursor;
GN   Name=GFY;
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:UniProtKB.
//
ID   GG12C_HUMAN             Reviewed;         117 AA.
AC   A1L429; A6NHF1; B7ZL74;
DE   RecName: Full=G antigen 12B/C/D/E;
DE            Short=GAGE-12B;
DE            Short=GAGE-12C;
DE            Short=GAGE-12D;
DE            Short=GAGE-12E;
GN   Name=GAGE12B;
GN   and
GN   Name=GAGE12C;
GN   and
GN   Name=GAGE12D;
GN   and
GN   Name=GAGE12E;
//
ID   GG12F_HUMAN             Reviewed;         117 AA.
AC   P0CL80; Q66I50;
DE   RecName: Full=G antigen 12F;
DE            Short=GAGE-12F;
GN   Name=GAGE12F;
//
ID   GG12G_HUMAN             Reviewed;         117 AA.
AC   P0CL81; Q66I50;
DE   RecName: Full=G antigen 12G;
DE            Short=GAGE-12G;
GN   Name=GAGE12G;
//
ID   GG12H_HUMAN             Reviewed;         117 AA.
AC   A6NDE8;
DE   RecName: Full=G antigen 12H;
DE            Short=GAGE-12H;
GN   Name=GAGE12H;
//
ID   GG12I_HUMAN             Reviewed;         117 AA.
AC   P0CL82; Q66I50;
DE   RecName: Full=G antigen 12I;
DE            Short=GAGE-12I;
GN   Name=GAGE12I;
//
ID   GG12J_HUMAN             Reviewed;         117 AA.
AC   A6NER3;
DE   RecName: Full=G antigen 12J;
DE            Short=GAGE-12J;
GN   Name=GAGE12J;
//
ID   GG2L2_HUMAN             Reviewed;         131 AA.
AC   Q9H5Y0; A6NLN5; Q6P168; Q96I56;
DE   RecName: Full=Golgin subfamily A member 2-like protein 2;
//
ID   GG2L3_HUMAN             Reviewed;         131 AA.
AC   Q8NCE8;
DE   RecName: Full=Golgin subfamily A member 2-like protein 3;
//
ID   GG2L5_HUMAN             Reviewed;         110 AA.
AC   A8MS94;
DE   RecName: Full=Putative golgin subfamily A member 2-like protein 5;
//
ID   GG6L1_HUMAN             Reviewed;         621 AA.
AC   Q8N7Z2;
DE   RecName: Full=Golgin subfamily A member 6-like protein 1;
GN   Name=GOLGA6L1;
//
ID   GG6L2_HUMAN             Reviewed;         650 AA.
AC   Q8N9W4; A1L301;
DE   RecName: Full=Golgin subfamily A member 6-like protein 2;
GN   Name=GOLGA6L2;
//
ID   GG6L3_HUMAN             Reviewed;         463 AA.
AC   A6NEY3;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 3;
GN   Name=GOLGA6L3;
//
ID   GG6L4_HUMAN             Reviewed;         574 AA.
AC   A6NEF3; D6REZ9;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 4;
GN   Name=GOLGA6L4;
//
ID   GG6L9_HUMAN             Reviewed;         432 AA.
AC   A6NEM1; Q8IVV3;
DE   RecName: Full=Golgin subfamily A member 6-like protein 9;
GN   Name=GOLGA6L9;
//
ID   GG6LA_HUMAN             Reviewed;         479 AA.
AC   A6NI86;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 10;
GN   Name=GOLGA6L10;
//
ID   GG6L6_HUMAN             Reviewed;         750 AA.
AC   A8MZA4; D3YTC0;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 6;
GN   Name=GOLGA6L6;
//
ID   GG6LR_HUMAN             Reviewed;         536 AA.
AC   D6RB28;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 18;
GN   Name=GOLGA6L18;
//
ID   GG6LS_HUMAN             Reviewed;         550 AA.
AC   H0YKK7;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 19;
GN   Name=GOLGA6L19;
//
ID   GG6LT_HUMAN             Reviewed;         444 AA.
AC   A6NFL8; H0YK89;
DE   RecName: Full=Putative golgin subfamily A member 6-like protein 20;
GN   Name=GOLGA6L20;
//
ID   GG6LV_HUMAN             Reviewed;         854 AA.
AC   H0YM25;
DE   RecName: Full=Golgin subfamily A member 6-like protein 22;
GN   Name=GOLGA6L22;
//
ID   GG8L2_HUMAN             Reviewed;         632 AA.
AC   A6NP81;
DE   RecName: Full=Golgin subfamily A member 8-like protein 2;
//
ID   GGA1_HUMAN              Reviewed;         639 AA.
AC   Q9UJY5; A8K3D3; B0QYR7; Q5TG07; Q86YA9; Q8NCS6; Q9BW94; Q9UG00;
AC   Q9UGW0; Q9UGW1;
DE   RecName: Full=ADP-ribosylation factor-binding protein GGA1;
DE   AltName: Full=Gamma-adaptin-related protein 1;
DE   AltName: Full=Golgi-localized, gamma ear-containing, ARF-binding protein 1;
GN   Name=GGA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   GGA2B_HUMAN             Reviewed;         144 AA.
AC   Q9HBQ8; Q9NSV2;
DE   RecName: Full=Putative golgin subfamily A member 2B;
DE   AltName: Full=Golgin subfamily A member 2-like protein 1;
GN   Name=GOLGA2P5; Synonyms=GOLGA2B, GOLGA2L1; ORFNames=PP1757;
//
ID   GGA2_HUMAN              Reviewed;         613 AA.
AC   Q9UJY4; D3DWF0; O14564; Q9NYN2; Q9UPS2;
DE   RecName: Full=ADP-ribosylation factor-binding protein GGA2;
DE   AltName: Full=Gamma-adaptin-related protein 2;
DE   AltName: Full=Golgi-localized, gamma ear-containing, ARF-binding protein 2;
DE   AltName: Full=VHS domain and ear domain of gamma-adaptin;
DE            Short=Vear;
GN   Name=GGA2; Synonyms=KIAA1080;
DR   GO; GO:0030306; F:ADP-ribosylation factor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   GGA3_HUMAN              Reviewed;         723 AA.
AC   Q9NZ52; B7Z7E2; B7Z7M9; J3KRN0; Q15017; Q6IS16; Q9UJY3;
DE   RecName: Full=ADP-ribosylation factor-binding protein GGA3;
DE   AltName: Full=Golgi-localized, gamma ear-containing, ARF-binding protein 3;
GN   Name=GGA3; Synonyms=KIAA0154;
DR   GO; GO:0030306; F:ADP-ribosylation factor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   GGACT_HUMAN             Reviewed;         153 AA.
AC   Q9BVM4; B3KTN1; Q9BT41;
DE   RecName: Full=Gamma-glutamylaminecyclotransferase;
DE            Short=GGACT;
DE            EC=2.3.2.4;
DE   AltName: Full=AIG2-like domain-containing protein 1;
DE   AltName: Full=Gamma-glutamylamine cyclotransferase;
GN   Name=GGACT; Synonyms=A2LD1;
DR   GO; GO:0003839; F:gamma-glutamylcyclotransferase activity; IDA:UniProtKB.
DR   GO; GO:0042219; P:cellular modified amino acid catabolic process; IDA:UniProtKB.
//
ID   GGCT_HUMAN              Reviewed;         188 AA.
AC   O75223; B2RDN0; B8ZZN4; B8ZZR8; Q9BS37;
DE   RecName: Full=Gamma-glutamylcyclotransferase;
DE            EC=2.3.2.4;
DE   AltName: Full=Cytochrome c-releasing factor 21;
GN   Name=GGCT; Synonyms=C7orf24, CRF21;
DR   GO; GO:0003839; F:gamma-glutamylcyclotransferase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006750; P:glutathione biosynthetic process; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GGE2D_HUMAN             Reviewed;         116 AA.
AC   Q9UEU5; A6NG46; A6NNR8; B7ZL76; Q4V325;
DE   RecName: Full=G antigen 2D;
DE            Short=GAGE-2D;
DE   AltName: Full=Cancer/testis antigen 4.8;
DE            Short=CT4.8;
DE   AltName: Full=G antigen 8;
DE            Short=GAGE-8;
GN   Name=GAGE2D;
GN   and
GN   Name=GAGE8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   GGEE3_HUMAN             Reviewed;         111 AA.
AC   Q5JRK9; A1L414;
DE   RecName: Full=Putative G antigen family E member 3;
DE   AltName: Full=Prostate-associated gene 2B protein;
DE            Short=PAGE-2B;
GN   Name=PAGE2B; Synonyms=GAGEE3;
//
ID   GGH_HUMAN               Reviewed;         318 AA.
AC   Q92820;
DE   RecName: Full=Gamma-glutamyl hydrolase;
DE            EC=3.4.19.9;
DE   AltName: Full=Conjugase;
DE   AltName: Full=GH;
DE   AltName: Full=Gamma-Glu-X carboxypeptidase;
DE   Flags: Precursor;
GN   Name=GGH;
DR   GO; GO:0008238; F:exopeptidase activity; TAS:ProtInc.
DR   GO; GO:0034722; F:gamma-glutamyl-peptidase activity; IDA:UniProtKB.
DR   GO; GO:0008242; F:omega peptidase activity; TAS:ProtInc.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IDA:GOC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
//
ID   GGNB1_HUMAN             Reviewed;         109 AA.
AC   Q5YKI7; Q5YKI8;
DE   RecName: Full=Putative gametogenetin-binding protein 1;
GN   Name=GGNBP1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0000266; P:mitochondrial fission; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   GGNB2_HUMAN             Reviewed;         697 AA.
AC   Q9H3C7; B2RPK7; Q96T90; Q9GZR8; Q9H767;
DE   RecName: Full=Gametogenetin-binding protein 2;
DE   AltName: Full=Laryngeal carcinoma-related protein 1;
DE   AltName: Full=Protein ZNF403;
GN   Name=GGNBP2; Synonyms=LCRG1, LZK1, ZNF403;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   GGN_HUMAN               Reviewed;         652 AA.
AC   Q86UU5; Q7RTU6; Q86UU4; Q8NAA1;
DE   RecName: Full=Gametogenetin;
GN   Name=GGN;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007276; P:gamete generation; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   GGPPS_HUMAN             Reviewed;         300 AA.
AC   O95749; Q5T2C8; Q6NW19;
DE   RecName: Full=Geranylgeranyl pyrophosphate synthase;
DE            Short=GGPP synthase;
DE            Short=GGPPSase;
DE            EC=2.5.1.-;
DE   AltName: Full=(2E,6E)-farnesyl diphosphate synthase;
DE   AltName: Full=Dimethylallyltranstransferase;
DE            EC=2.5.1.1;
DE   AltName: Full=Farnesyl diphosphate synthase;
DE   AltName: Full=Farnesyltranstransferase;
DE            EC=2.5.1.29;
DE   AltName: Full=Geranylgeranyl diphosphate synthase;
DE   AltName: Full=Geranyltranstransferase;
DE            EC=2.5.1.10;
GN   Name=GGPS1;
DR   GuidetoPHARMACOLOGY; 643; -.
DR   GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004311; F:farnesyltranstransferase activity; IDA:UniProtKB.
DR   GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0045337; P:farnesyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0033384; P:geranyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0033386; P:geranylgeranyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006720; P:isoprenoid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GGT1_HUMAN              Reviewed;         569 AA.
AC   P19440; Q08247; Q14404; Q8TBS1; Q9UMK1;
DE   RecName: Full=Gamma-glutamyltranspeptidase 1;
DE            Short=GGT 1;
DE            EC=2.3.2.2;
DE   AltName: Full=Gamma-glutamyltransferase 1;
DE   AltName: Full=Glutathione hydrolase 1;
DE            EC=3.4.19.13;
DE   AltName: Full=Leukotriene-C4 hydrolase;
DE            EC=3.4.19.14;
DE   AltName: CD_antigen=CD224;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltranspeptidase 1 heavy chain;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltranspeptidase 1 light chain;
DE   Flags: Precursor;
GN   Name=GGT1; Synonyms=GGT;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006750; P:glutathione biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006751; P:glutathione catabolic process; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0002682; P:regulation of immune system process; ISS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
DR   GO; GO:0031638; P:zymogen activation; IDA:UniProtKB.
//
ID   GGT2_HUMAN              Reviewed;         569 AA.
AC   P36268;
DE   RecName: Full=Inactive gamma-glutamyltranspeptidase 2;
DE            Short=GGT 2;
DE   AltName: Full=Gamma-glutamyltransferase 2;
DE   AltName: Full=Glutathione hydrolase 2;
DE   Flags: Precursor;
GN   Name=GGT2;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0006750; P:glutathione biosynthetic process; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GGT3_HUMAN              Reviewed;         568 AA.
AC   A6NGU5;
DE   RecName: Full=Putative gamma-glutamyltranspeptidase 3;
DE            Short=GGT 3;
DE            EC=2.3.2.2;
DE   AltName: Full=Gamma-glutamyltransferase 3;
DE   AltName: Full=Glutathione hydrolase 3;
DE            EC=3.4.19.13;
DE   Contains:
DE     RecName: Full=Putative gamma-glutamyltranspeptidase 3 heavy chain;
DE   Contains:
DE     RecName: Full=Putative gamma-glutamyltranspeptidase 3 light chain;
DE   Flags: Precursor;
GN   Name=GGT3P; Synonyms=GGT3;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
//
ID   GGT5_HUMAN              Reviewed;         586 AA.
AC   P36269; Q53XM9; Q6GMP0; Q96FC1; Q9UFM5;
DE   RecName: Full=Gamma-glutamyltransferase 5;
DE            Short=GGT 5;
DE            EC=2.3.2.2;
DE   AltName: Full=Gamma-glutamyl transpeptidase-related enzyme;
DE            Short=GGT-rel;
DE   AltName: Full=Gamma-glutamyltransferase-like activity 1;
DE   AltName: Full=Gamma-glutamyltranspeptidase 5;
DE   AltName: Full=Glutathione hydrolase 5;
DE            EC=3.4.19.13;
DE   AltName: Full=Leukotriene-C4 hydrolase;
DE            EC=3.4.19.14;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltransferase 5 heavy chain;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltransferase 5 light chain;
DE   Flags: Precursor;
GN   Name=GGT5; Synonyms=GGTLA1;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GGT6_HUMAN              Reviewed;         493 AA.
AC   Q6P531; B4DUH4; Q8NCM0;
DE   RecName: Full=Gamma-glutamyltransferase 6;
DE            Short=GGT 6;
DE            EC=2.3.2.2;
DE   AltName: Full=Gamma-glutamyltranspeptidase 6;
DE   AltName: Full=Glutathione hydrolase 6;
DE            EC=3.4.19.13;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltransferase 6 heavy chain;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltransferase 6 light chain;
DE   Flags: Precursor;
GN   Name=GGT6;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
//
ID   GGT7_HUMAN              Reviewed;         662 AA.
AC   Q9UJ14; Q8N899; Q8NF66; Q9BYP5; Q9BYP6;
DE   RecName: Full=Gamma-glutamyltransferase 7;
DE            Short=GGT 7;
DE            EC=2.3.2.2;
DE   AltName: Full=Gamma-glutamyltransferase-like 3;
DE   AltName: Full=Gamma-glutamyltransferase-like 5;
DE   AltName: Full=Gamma-glutamyltranspeptidase 7;
DE   AltName: Full=Glutathione hydrolase 7;
DE            EC=3.4.19.13;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltransferase 7 heavy chain;
DE   Contains:
DE     RecName: Full=Gamma-glutamyltransferase 7 light chain;
DE   Flags: Precursor;
GN   Name=GGT7; Synonyms=GGTL3, GGTL5;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
//
ID   GGTA1_HUMAN             Reviewed;         100 AA.
AC   Q4G0N0; A2JVH9;
DE   RecName: Full=Inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase;
DE   AltName: Full=Glycoprotein alpha-galactosyltransferase 1 pseudogene;
GN   Name=GGTA1P; Synonyms=GGTA1;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0033580; P:protein galactosylation at cell surface; ISS:UniProtKB.
//
ID   GGTL1_HUMAN             Reviewed;         225 AA.
AC   Q9BX51; D3DW43; Q08246;
DE   RecName: Full=Gamma-glutamyltransferase light chain 1;
DE   AltName: Full=Gamma-glutamyltransferase-like activity 4;
DE   AltName: Full=Gamma-glutamyltransferase-like protein 6;
GN   Name=GGTLC1; Synonyms=GGTLA4;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
//
ID   GGTL2_HUMAN             Reviewed;         218 AA.
AC   Q14390; A1A516; A2VCM9; Q5NV76; Q6ISH0;
DE   RecName: Full=Gamma-glutamyltransferase light chain 2;
DE   AltName: Full=Gamma-glutamyltransferase-like protein 4;
GN   Name=GGTLC2; Synonyms=GGTL4;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; NAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
//
ID   GGTL3_HUMAN             Reviewed;         225 AA.
AC   B5MD39; A6NEA2;
DE   RecName: Full=Putative gamma-glutamyltransferase light chain 3;
GN   Name=GGTLC3;
DR   GO; GO:0003840; F:gamma-glutamyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:UniProtKB.
//
ID   GHC1_HUMAN              Reviewed;         323 AA.
AC   Q9H936; A8K366; C9J1H6; E9PJD3; E9PKB2; E9PL68; E9PN26; E9PNQ3;
AC   E9PP01; E9PR97; Q8TBU8;
DE   RecName: Full=Mitochondrial glutamate carrier 1;
DE            Short=GC-1;
DE   AltName: Full=Glutamate/H(+) symporter 1;
DE   AltName: Full=Solute carrier family 25 member 22;
GN   Name=SLC25A22; Synonyms=GC1;
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015813; P:L-glutamate transport; IDA:UniProtKB.
//
ID   GHC2_HUMAN              Reviewed;         315 AA.
AC   Q9H1K4;
DE   RecName: Full=Mitochondrial glutamate carrier 2;
DE            Short=GC-2;
DE   AltName: Full=Glutamate/H(+) symporter 2;
DE   AltName: Full=Solute carrier family 25 member 18;
GN   Name=SLC25A18; Synonyms=GC2;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
//
ID   GHDC_HUMAN              Reviewed;         530 AA.
AC   Q8N2G8; B4DQS4; E9PDB5; Q9BXM6;
DE   RecName: Full=GH3 domain-containing protein;
DE   Flags: Precursor;
GN   Name=GHDC; Synonyms=D11LGP1E, LGP1;
//
ID   GHITM_HUMAN             Reviewed;         345 AA.
AC   Q9H3K2; A8K9Z9; D3DWE0; O95894; Q5VT95; Q9H0P2;
DE   RecName: Full=Growth hormone-inducible transmembrane protein;
DE   AltName: Full=Dermal papilla-derived protein 2;
DE   AltName: Full=Mitochondrial morphology and cristae structure 1;
DE            Short=MICS1;
DE   AltName: Full=Transmembrane BAX inhibitor motif-containing protein 5;
DE   Flags: Precursor;
GN   Name=GHITM; Synonyms=DERP2, MICS1, TMBIM5;
GN   ORFNames=My021, UNQ244/PRO281;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   GHRHR_HUMAN             Reviewed;         423 AA.
AC   Q02643; Q99863;
DE   RecName: Full=Growth hormone-releasing hormone receptor;
DE            Short=GHRH receptor;
DE   AltName: Full=Growth hormone-releasing factor receptor;
DE            Short=GRF receptor;
DE            Short=GRFR;
DE   Flags: Precursor;
GN   Name=GHRHR;
DR   GuidetoPHARMACOLOGY; 247; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IC:BHF-UCL.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0016520; F:growth hormone-releasing hormone receptor activity; IMP:BHF-UCL.
DR   GO; GO:0017046; F:peptide hormone binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IMP:BHF-UCL.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0030252; P:growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0048609; P:multicellular organismal reproductive process; NAS:BHF-UCL.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; NAS:BHF-UCL.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IMP:BHF-UCL.
DR   GO; GO:0033143; P:regulation of intracellular steroid hormone receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051246; P:regulation of protein metabolic process; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IDA:BHF-UCL.
DR   GO; GO:0051384; P:response to glucocorticoid; IDA:BHF-UCL.
DR   GO; GO:0032868; P:response to insulin; IMP:BHF-UCL.
DR   GO; GO:0060133; P:somatotropin secreting cell development; IEA:Ensembl.
DR   GO; GO:0030104; P:water homeostasis; IEA:Ensembl.
//
ID   GHRL_HUMAN              Reviewed;         117 AA.
AC   Q9UBU3; A8CF34; A8CF38; A8CF42; A8DN29; A8DN30; Q86YP8; Q8TAT9;
AC   Q9H3R3;
DE   RecName: Full=Appetite-regulating hormone;
DE   AltName: Full=Growth hormone secretagogue;
DE   AltName: Full=Growth hormone-releasing peptide;
DE   AltName: Full=Motilin-related peptide;
DE   AltName: Full=Protein M46;
DE   Contains:
DE     RecName: Full=Ghrelin-27;
DE   Contains:
DE     RecName: Full=Ghrelin-28;
DE              Short=Ghrelin;
DE   Contains:
DE     RecName: Full=Obestatin;
DE   Flags: Precursor;
GN   Name=GHRL; Synonyms=MTLRP; ORFNames=UNQ524/PRO1066;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; ISS:UniProtKB.
DR   GO; GO:0031768; F:ghrelin receptor binding; ISS:UniProtKB.
DR   GO; GO:0016608; F:growth hormone-releasing hormone activity; ISS:UniProtKB.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IMP:UniProtKB.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IMP:UniProtKB.
DR   GO; GO:0008343; P:adult feeding behavior; ISS:HGNC.
DR   GO; GO:0051216; P:cartilage development; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043400; P:cortisol secretion; NAS:UniProtKB.
DR   GO; GO:0046697; P:decidualization; IDA:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IDA:MGI.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001696; P:gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; NAS:UniProtKB.
DR   GO; GO:0030252; P:growth hormone secretion; TAS:HGNC.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; TAS:HGNC.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0042322; P:negative regulation of circadian sleep/wake cycle, REM sleep; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IDA:UniProtKB.
DR   GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0040013; P:negative regulation of locomotion; IEA:Ensembl.
DR   GO; GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032100; P:positive regulation of appetite; ISS:HGNC.
DR   GO; GO:0046010; P:positive regulation of circadian sleep/wake cycle, non-REM sleep; IDA:BHF-UCL.
DR   GO; GO:0051461; P:positive regulation of corticotropin secretion; IDA:BHF-UCL.
DR   GO; GO:0051464; P:positive regulation of cortisol secretion; IDA:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:UniProtKB.
DR   GO; GO:0060399; P:positive regulation of growth hormone receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IC:HGNC.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IMP:GOC.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IDA:MGI.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
//
ID   GHR_HUMAN               Reviewed;         638 AA.
AC   P10912; Q9HCX2;
DE   RecName: Full=Growth hormone receptor;
DE            Short=GH receptor;
DE   AltName: Full=Somatotropin receptor;
DE   Contains:
DE     RecName: Full=Growth hormone-binding protein;
DE              Short=GH-binding protein;
DE              Short=GHBP;
DE     AltName: Full=Serum-binding protein;
DE   Flags: Precursor;
GN   Name=GHR;
DR   GuidetoPHARMACOLOGY; 1720; -.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0004903; F:growth hormone receptor activity; IEA:Ensembl.
DR   GO; GO:0017046; F:peptide hormone binding; IPI:BHF-UCL.
DR   GO; GO:0070064; F:proline-rich region binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; ISS:BHF-UCL.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0042977; P:activation of JAK2 kinase activity; ISS:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.
DR   GO; GO:0000255; P:allantoin metabolic process; ISS:BHF-UCL.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IMP:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0006101; P:citrate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006600; P:creatine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046449; P:creatinine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0006549; P:isoleucine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; ISS:BHF-UCL.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0044236; P:multicellular organismal metabolic process; IMP:BHF-UCL.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IMP:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; ISS:BHF-UCL.
DR   GO; GO:0031623; P:receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:BHF-UCL.
DR   GO; GO:0046898; P:response to cycloheximide; IDA:BHF-UCL.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0006105; P:succinate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0019530; P:taurine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006573; P:valine metabolic process; ISS:BHF-UCL.
//
ID   GHSR_HUMAN              Reviewed;         366 AA.
AC   Q92847; Q14D12; Q6ISR8; Q92848; Q96RJ7;
DE   RecName: Full=Growth hormone secretagogue receptor type 1;
DE            Short=GHS-R;
DE   AltName: Full=GH-releasing peptide receptor;
DE            Short=GHRP;
DE   AltName: Full=Ghrelin receptor;
GN   Name=GHSR;
DR   GuidetoPHARMACOLOGY; 246; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:HGNC.
DR   GO; GO:0001616; F:growth hormone secretagogue receptor activity; IDA:HGNC.
DR   GO; GO:0016520; F:growth hormone-releasing hormone receptor activity; IDA:HGNC.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; IDA:UniProtKB.
DR   GO; GO:0008343; P:adult feeding behavior; ISS:HGNC.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0030252; P:growth hormone secretion; TAS:HGNC.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IDA:HGNC.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IDA:UniProtKB.
DR   GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032100; P:positive regulation of appetite; ISS:HGNC.
DR   GO; GO:0045923; P:positive regulation of fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IMP:HGNC.
DR   GO; GO:0043134; P:regulation of hindgut contraction; IEA:Ensembl.
DR   GO; GO:0051963; P:regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
//
ID   GI24_HUMAN              Reviewed;         311 AA.
AC   Q9H7M9; A1L0X9; A4ZYV1; A8MVH5; Q6UXF3; Q8WUG3; Q8WYZ8;
DE   RecName: Full=Platelet receptor Gi24;
DE   AltName: Full=Stress-induced secreted protein-1;
DE            Short=Sisp-1;
DE   Flags: Precursor;
GN   Name=C10orf54; Synonyms=SISP1; ORFNames=PP2135, UNQ730/PRO1412;
//
ID   GID4_HUMAN              Reviewed;         300 AA.
AC   Q8IVV7; Q8TEB5; Q9BW50;
DE   RecName: Full=Glucose-induced degradation protein 4 homolog;
DE   AltName: Full=Vacuolar import and degradation protein 24 homolog;
GN   Name=GID4; Synonyms=C17orf39, VID24;
//
ID   GID8_HUMAN              Reviewed;         228 AA.
AC   Q9NWU2; E1P5I3; Q8N5M5;
DE   RecName: Full=Glucose-induced degradation protein 8 homolog;
DE   AltName: Full=Two hybrid-associated protein 1 with RanBPM;
DE            Short=Twa1;
GN   Name=GID8; Synonyms=C20orf11;
//
ID   GILT_HUMAN              Reviewed;         250 AA.
AC   P13284; Q76MF9; Q8NEI4; Q8WU77; Q9UL08;
DE   RecName: Full=Gamma-interferon-inducible lysosomal thiol reductase;
DE            EC=1.8.-.-;
DE   AltName: Full=Gamma-interferon-inducible protein IP-30;
DE   AltName: Full=Legumaturain;
DE   Flags: Precursor;
GN   Name=IFI30; Synonyms=GILT, IP30;
DR   GO; GO:0016667; F:oxidoreductase activity, acting on a sulfur group of donors; IMP:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; ISS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
//
ID   GIMA1_HUMAN             Reviewed;         306 AA.
AC   Q8WWP7; B2RCI3; Q8NAZ0;
DE   RecName: Full=GTPase IMAP family member 1;
DE   AltName: Full=Immunity-associated protein 1;
DE            Short=hIMAP1;
GN   Name=GIMAP1; Synonyms=IMAP1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
//
ID   GIMA2_HUMAN             Reviewed;         337 AA.
AC   Q9UG22; Q96L25;
DE   RecName: Full=GTPase IMAP family member 2;
DE   AltName: Full=Immunity-associated protein 2;
DE            Short=hIMAP2;
GN   Name=GIMAP2; Synonyms=IMAP2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GIMA4_HUMAN             Reviewed;         329 AA.
AC   Q9NUV9;
DE   RecName: Full=GTPase IMAP family member 4;
DE   AltName: Full=Immunity-associated nucleotide 1 protein;
DE            Short=IAN-1;
DE            Short=hIAN1;
DE   AltName: Full=Immunity-associated protein 4;
GN   Name=GIMAP4; Synonyms=IAN1, IMAP4; ORFNames=MSTP062;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GIMA5_HUMAN             Reviewed;         307 AA.
AC   Q96F15; D3DWZ5; Q6IA75; Q96NE4; Q9NUK9;
DE   RecName: Full=GTPase IMAP family member 5;
DE   AltName: Full=Immunity-associated nucleotide 4-like 1 protein;
DE   AltName: Full=Immunity-associated nucleotide 5 protein;
DE            Short=IAN-5;
DE            Short=hIAN5;
DE   AltName: Full=Immunity-associated protein 3;
GN   Name=GIMAP5; Synonyms=IAN4L1, IAN5, IMAP3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IEA:Ensembl.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:0032831; P:positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0045838; P:positive regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0002729; P:positive regulation of natural killer cell cytokine production; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
//
ID   GIMA6_HUMAN             Reviewed;         292 AA.
AC   Q6P9H5; C9J7B6; D3DWZ4; Q5ZPR6; Q9H612;
DE   RecName: Full=GTPase IMAP family member 6;
DE   AltName: Full=Immunity-associated nucleotide 2 protein;
DE            Short=IAN-2;
DE            Short=hIAN2;
DE   AltName: Full=Immunity-associated nucleotide 6 protein;
DE            Short=IAN-6;
DE            Short=hIAN6;
GN   Name=GIMAP6; Synonyms=IAN2, IAN6;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GIMA7_HUMAN             Reviewed;         300 AA.
AC   Q8NHV1;
DE   RecName: Full=GTPase IMAP family member 7;
DE   AltName: Full=Immunity-associated nucleotide 7 protein;
DE            Short=IAN-7;
GN   Name=GIMAP7; Synonyms=IAN7;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
//
ID   GIMA8_HUMAN             Reviewed;         665 AA.
AC   Q8ND71;
DE   RecName: Full=GTPase IMAP family member 8;
DE   AltName: Full=Immune-associated nucleotide-binding protein 9;
DE            Short=IAN-9;
DE   AltName: Full=Protein IanT;
GN   Name=GIMAP8; Synonyms=IAN9, IANT;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GIMD1_HUMAN             Reviewed;         217 AA.
AC   P0DJR0;
DE   RecName: Full=GTPase IMAP family member GIMD1;
DE   AltName: Full=GIMAP family P-loop NTPase domain-containing protein 1;
GN   Name=GIMD1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GIN1_HUMAN              Reviewed;         522 AA.
AC   Q9NXP7; B2RXF7; B4DIV4; Q6AI03; Q96BR2;
DE   RecName: Full=Gypsy retrotransposon integrase-like protein 1;
DE            Short=GIN-1;
DE   AltName: Full=Ty3/Gypsy integrase 1;
DE   AltName: Full=Zinc finger H2C2 domain-containing protein;
GN   Name=GIN1; Synonyms=TGIN1, ZH2C2;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
//
ID   GINM1_HUMAN             Reviewed;         330 AA.
AC   Q9NU53; B2RDY7; E1P5A2;
DE   RecName: Full=Glycoprotein integral membrane protein 1;
DE   Flags: Precursor;
GN   Name=GINM1; Synonyms=C6orf72; ORFNames=UNQ710/PRO1361;
//
ID   GIPC1_HUMAN             Reviewed;         333 AA.
AC   O14908; A8K4I3; A8MZG3; Q9BTC9;
DE   RecName: Full=PDZ domain-containing protein GIPC1;
DE   AltName: Full=GAIP C-terminus-interacting protein;
DE   AltName: Full=RGS-GAIP-interacting protein;
DE   AltName: Full=RGS19-interacting protein 1;
DE   AltName: Full=Synectin;
DE   AltName: Full=Tax interaction protein 2;
DE            Short=TIP-2;
GN   Name=GIPC1; Synonyms=C19orf3, GIPC, RGS19IP1;
DR   GO; GO:0003779; F:actin binding; ISS:BHF-UCL.
DR   GO; GO:0017022; F:myosin binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; ISS:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0014047; P:glutamate secretion; ISS:BHF-UCL.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0006605; P:protein targeting; ISS:BHF-UCL.
DR   GO; GO:0031647; P:regulation of protein stability; ISS:BHF-UCL.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; ISS:BHF-UCL.
//
ID   GIPC2_HUMAN             Reviewed;         315 AA.
AC   Q8TF65; Q8IYD3; Q9NXS7;
DE   RecName: Full=PDZ domain-containing protein GIPC2;
GN   Name=GIPC2;
//
ID   GIPC3_HUMAN             Reviewed;         312 AA.
AC   Q8TF64; O75227;
DE   RecName: Full=PDZ domain-containing protein GIPC3;
GN   Name=GIPC3; Synonyms=C19orf64;
//
ID   GIPR_HUMAN              Reviewed;         466 AA.
AC   P48546; B7WP14; B7ZKQ0; Q14401; Q16400; Q52M04; Q9UPI1;
DE   RecName: Full=Gastric inhibitory polypeptide receptor;
DE            Short=GIP-R;
DE   AltName: Full=Glucose-dependent insulinotropic polypeptide receptor;
DE   Flags: Precursor;
GN   Name=GIPR;
DR   GuidetoPHARMACOLOGY; 248; -.
DR   GO; GO:0016519; F:gastric inhibitory peptide receptor activity; IEA:Ensembl.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
//
ID   GIP_HUMAN               Reviewed;         153 AA.
AC   P09681; Q4VB42; Q6NTD3;
DE   RecName: Full=Gastric inhibitory polypeptide;
DE            Short=GIP;
DE   AltName: Full=Glucose-dependent insulinotropic polypeptide;
DE   AltName: Full=Incretin hormone;
DE   Flags: Precursor;
GN   Name=GIP;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0055123; P:digestive system development; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0035640; P:exploration behavior; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0070094; P:positive regulation of glucagon secretion; IEA:Ensembl.
DR   GO; GO:0010828; P:positive regulation of glucose transport; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0033993; P:response to lipid; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0010269; P:response to selenium ion; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0070328; P:triglyceride homeostasis; IEA:Ensembl.
//
ID   GIT1_HUMAN              Reviewed;         761 AA.
AC   Q9Y2X7; B4DGU9; B4DSV3; Q86SS0; Q9BRJ4;
DE   RecName: Full=ARF GTPase-activating protein GIT1;
DE            Short=ARF GAP GIT1;
DE   AltName: Full=Cool-associated and tyrosine-phosphorylated protein 1;
DE            Short=CAT-1;
DE            Short=CAT1;
DE   AltName: Full=G protein-coupled receptor kinase-interactor 1;
DE   AltName: Full=GRK-interacting protein 1;
GN   Name=GIT1;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
//
ID   GIT2_HUMAN              Reviewed;         759 AA.
AC   Q14161; Q86U59; Q96CI2; Q9BV91; Q9Y5V2;
DE   RecName: Full=ARF GTPase-activating protein GIT2;
DE            Short=ARF GAP GIT2;
DE   AltName: Full=Cool-interacting tyrosine-phosphorylated protein 2;
DE            Short=CAT-2;
DE            Short=CAT2;
DE   AltName: Full=G protein-coupled receptor kinase-interactor 2;
DE   AltName: Full=GRK-interacting protein 2;
GN   Name=GIT2; Synonyms=KIAA0148;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
//
ID   GKAP1_HUMAN             Reviewed;         366 AA.
AC   Q5VSY0; Q96LI0; Q9BYI1; Q9BYI2; Q9H225;
DE   RecName: Full=G kinase-anchoring protein 1;
DE   AltName: Full=cGMP-dependent protein kinase-anchoring protein of 42 kDa;
GN   Name=GKAP1; Synonyms=GKAP42; ORFNames=FKSG21;
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
//
ID   GKN1_HUMAN              Reviewed;         199 AA.
AC   Q9NS71; Q8IUA9;
DE   RecName: Full=Gastrokine-1;
DE   AltName: Full=18 kDa antrum mucosa protein;
DE            Short=AMP-18;
DE   AltName: Full=Protein CA11;
DE   Flags: Precursor;
GN   Name=GKN1; Synonyms=AMP18, CA11; ORFNames=UNQ489/PRO1005;
DR   GO; GO:0007586; P:digestion; NAS:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   GKN2_HUMAN              Reviewed;         184 AA.
AC   Q86XP6; Q6UWS6;
DE   RecName: Full=Gastrokine-2;
DE   AltName: Full=Blottin;
DE   AltName: Full=Down-regulated in gastric cancer;
DE   AltName: Full=Trefoil factor interactions(z) 1;
DE   Flags: Precursor;
GN   Name=GKN2; Synonyms=BLOT, GDDR, TFIZ1; ORFNames=UNQ465/PRO813;
//
ID   GKN3_HUMAN              Reviewed;         181 AA.
AC   P0CG01;
DE   RecName: Full=Gastrokine-3;
DE   Flags: Precursor;
GN   Name=GKN3P;
//
ID   GL1AD_HUMAN             Reviewed;         148 AA.
AC   Q6EEV4; Q6EEV7;
DE   RecName: Full=DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5;
DE   AltName: Full=DNA-directed RNA polymerase II subunit M, isoforms 4/5;
GN   Name=POLR2M; Synonyms=GRINL1A;
//
ID   GL1D1_HUMAN             Reviewed;         346 AA.
AC   Q96MS3; Q86XG8;
DE   RecName: Full=Glycosyltransferase 1 domain-containing protein 1;
DE            EC=2.4.-.-;
DE   Flags: Precursor;
GN   Name=GLT1D1;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
//
ID   GL54D_HUMAN             Reviewed;         374 AA.
AC   A6NG13;
DE   RecName: Full=Glycosyltransferase 54 domain-containing protein;
DE            EC=2.4.1.-;
DE   Flags: Precursor;
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   GL6D1_HUMAN             Reviewed;         308 AA.
AC   Q7Z4J2;
DE   RecName: Full=Glycosyltransferase 6 domain-containing protein 1;
DE            EC=2.4.1.-;
DE   AltName: Full=Galactosyltransferase family 6 domain-containing 1;
GN   Name=GLT6D1; Synonyms=GLTDC1, GT6M7;
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   GL8D1_HUMAN             Reviewed;         371 AA.
AC   Q68CQ7; Q7Z4D1; Q8N2J6; Q9P0I5;
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 1;
DE            EC=2.4.1.-;
GN   Name=GLT8D1; Synonyms=GALA4A;
GN   ORFNames=AD-017, MSTP137, UNQ572/PRO1134;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   GL8D2_HUMAN             Reviewed;         349 AA.
AC   Q9H1C3; Q96KA2;
DE   RecName: Full=Glycosyltransferase 8 domain-containing protein 2;
DE            EC=2.4.1.-;
GN   Name=GLT8D2; Synonyms=GALA4A; ORFNames=UNQ1901/PRO4347;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
//
ID   GLB1L_HUMAN             Reviewed;         654 AA.
AC   Q6UWU2; Q96DR0;
DE   RecName: Full=Beta-galactosidase-1-like protein;
DE            EC=3.2.1.-;
DE   Flags: Precursor;
GN   Name=GLB1L; ORFNames=UNQ229/PRO262;
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   GLBL2_HUMAN             Reviewed;         636 AA.
AC   Q8IW92; A6NCE6; Q6UX60; Q8NC62; Q8NCB3; Q8NCJ1; Q96HP3;
DE   RecName: Full=Beta-galactosidase-1-like protein 2;
DE            EC=3.2.1.-;
DE   Flags: Precursor;
GN   Name=GLB1L2; ORFNames=MSTP014, UNQ210/PRO236;
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   GLBL3_HUMAN             Reviewed;         653 AA.
AC   Q8NCI6; A6NEM0; A6NN15; Q6P3S3; Q96FF8;
DE   RecName: Full=Beta-galactosidase-1-like protein 3;
DE            EC=3.2.1.-;
GN   Name=GLB1L3;
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   GLCE_HUMAN              Reviewed;         617 AA.
AC   O94923; Q6GUQ2;
DE   RecName: Full=D-glucuronyl C5-epimerase;
DE            EC=5.1.3.17;
DE   AltName: Full=Heparan sulfate C5-epimerase;
DE            Short=Hsepi;
DE   AltName: Full=Heparin/heparan sulfate:glucuronic acid C5-epimerase;
DE   AltName: Full=Heparosan-N-sulfate-glucuronate 5-epimerase;
GN   Name=GLCE; Synonyms=KIAA0836;
DR   GO; GO:0047464; F:heparosan-N-sulfate-glucuronate 5-epimerase activity; IMP:UniProtKB.
DR   GO; GO:0016857; F:racemase and epimerase activity, acting on carbohydrates and derivatives; ISS:UniProtKB.
DR   GO; GO:0050379; F:UDP-glucuronate 5'-epimerase activity; IDA:HGNC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030210; P:heparin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLCI1_HUMAN             Reviewed;         547 AA.
AC   Q86VQ1; A4D103; Q96FD0;
DE   RecName: Full=Glucocorticoid-induced transcript 1 protein;
GN   Name=GLCCI1;
//
ID   GLCM1_HUMAN             Reviewed;          47 AA.
AC   Q8IVK1; Q8IUA8;
DE   RecName: Full=Putative glycosylation-dependent cell adhesion molecule 1;
DE            Short=GlyCAM-1;
DE   Flags: Precursor;
GN   Name=GLYCAM1;
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   GLCM_HUMAN              Reviewed;         536 AA.
AC   P04062; A8K796; B7Z5G2; B7Z6S1; J3KQG4; J3KQK9; Q16545; Q4VX22;
AC   Q6I9R6; Q9UMJ8;
DE   RecName: Full=Glucosylceramidase;
DE            EC=3.2.1.45;
DE   AltName: Full=Acid beta-glucosidase;
DE   AltName: Full=Alglucerase;
DE   AltName: Full=Beta-glucocerebrosidase;
DE            Short=Beta-GC;
DE   AltName: Full=D-glucosyl-N-acylsphingosine glucohydrolase;
DE   AltName: Full=Imiglucerase;
DE   Flags: Precursor;
GN   Name=GBA; Synonyms=GC, GLUC;
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0006680; P:glucosylceramide catabolic process; IMP:BHF-UCL.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.
DR   GO; GO:0033561; P:regulation of water loss via skin; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0097066; P:response to thyroid hormone; IEA:Ensembl.
DR   GO; GO:0043589; P:skin morphogenesis; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0023021; P:termination of signal transduction; IMP:BHF-UCL.
//
ID   GLCNE_HUMAN             Reviewed;         722 AA.
AC   Q9Y223; A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7;
AC   F5H499; H0YFA7; Q0VA94;
DE   RecName: Full=Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase;
DE   AltName: Full=UDP-GlcNAc-2-epimerase/ManAc kinase;
DE   Includes:
DE     RecName: Full=UDP-N-acetylglucosamine 2-epimerase (hydrolyzing);
DE              EC=3.2.1.183;
DE     AltName: Full=UDP-GlcNAc-2-epimerase;
DE     AltName: Full=Uridine diphosphate-N-acetylglucosamine-2-epimerase;
DE   Includes:
DE     RecName: Full=N-acetylmannosamine kinase;
DE              EC=2.7.1.60;
DE     AltName: Full=ManAc kinase;
GN   Name=GNE; Synonyms=GLCNE;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009384; F:N-acylmannosamine kinase activity; IEA:InterPro.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; TAS:GOC.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0006045; P:N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046380; P:N-acetylneuraminate biosynthetic process; IEA:InterPro.
DR   GO; GO:0006054; P:N-acetylneuraminate metabolic process; TAS:ProtInc.
DR   GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; IEA:InterPro.
//
ID   GLCTK_HUMAN             Reviewed;         523 AA.
AC   Q8IVS8; Q0P630; Q2EZ43; Q6Y2K6; Q7Z6G5; Q86YR8; Q8TED2; Q8WTY2;
DE   RecName: Full=Glycerate kinase;
DE            EC=2.7.1.31;
DE   AltName: Full=HBeAg-binding protein 4;
GN   Name=GLYCTK; Synonyms=HBEBP4; ORFNames=LP5910;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008887; F:glycerate kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   GLD2_HUMAN              Reviewed;         484 AA.
AC   Q6PIY7; Q86WZ2; Q8N927;
DE   RecName: Full=Poly(A) RNA polymerase GLD2;
DE            Short=hGLD-2;
DE            EC=2.7.7.19;
DE   AltName: Full=PAP-associated domain-containing protein 4;
DE   AltName: Full=Terminal uridylyltransferase 2;
DE            Short=TUTase 2;
GN   Name=PAPD4; Synonyms=GLD2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043631; P:RNA polyadenylation; IDA:UniProtKB.
//
ID   GLDN_HUMAN              Reviewed;         551 AA.
AC   Q6ZMI3; Q6UXZ7; Q7Z359;
DE   RecName: Full=Gliomedin;
GN   Name=GLDN; Synonyms=COLM; ORFNames=UNQ9339/PRO34011;
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; IEA:Ensembl.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0032528; P:microvillus organization; IEA:Ensembl.
//
ID   GLE1_HUMAN              Reviewed;         698 AA.
AC   Q53GS7; O75458; Q53GT9; Q5VVU1; Q8NCP6; Q9UFL6;
DE   RecName: Full=Nucleoporin GLE1;
DE            Short=hGLE1;
DE   AltName: Full=GLE1-like protein;
GN   Name=GLE1; Synonyms=GLE1L;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   GLEM_HUMAN              Reviewed;          10 AA.
AC   P02728;
DE   RecName: Full=Erythrocyte membrane glycopeptide;
//
ID   GLGB_HUMAN              Reviewed;         702 AA.
AC   Q04446; B3KWV3; Q96EN0;
DE   RecName: Full=1,4-alpha-glucan-branching enzyme;
DE            EC=2.4.1.18;
DE   AltName: Full=Brancher enzyme;
DE   AltName: Full=Glycogen-branching enzyme;
GN   Name=GBE1;
DR   GO; GO:0003844; F:1,4-alpha-glucan branching enzyme activity; TAS:ProtInc.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLHA_HUMAN              Reviewed;         116 AA.
AC   P01215;
DE   RecName: Full=Glycoprotein hormones alpha chain;
DE   AltName: Full=Anterior pituitary glycoprotein hormones common subunit alpha;
DE   AltName: Full=Choriogonadotropin alpha chain;
DE   AltName: Full=Chorionic gonadotrophin subunit alpha;
DE            Short=CG-alpha;
DE   AltName: Full=Follicle-stimulating hormone alpha chain;
DE            Short=FSH-alpha;
DE   AltName: Full=Follitropin alpha chain;
DE   AltName: Full=Luteinizing hormone alpha chain;
DE            Short=LSH-alpha;
DE   AltName: Full=Lutropin alpha chain;
DE   AltName: Full=Thyroid-stimulating hormone alpha chain;
DE            Short=TSH-alpha;
DE   AltName: Full=Thyrotropin alpha chain;
DE   Flags: Precursor;
GN   Name=CGA;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0046884; P:follicle-stimulating hormone secretion; IEA:Ensembl.
DR   GO; GO:0008406; P:gonad development; IEA:Ensembl.
DR   GO; GO:0032275; P:luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; NAS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006590; P:thyroid hormone generation; IEA:Ensembl.
//
ID   GLI1_HUMAN              Reviewed;        1106 AA.
AC   P08151; D0EUY3; E9PQQ9; F5H6H8; Q8TDN9;
DE   RecName: Full=Zinc finger protein GLI1;
DE   AltName: Full=Glioma-associated oncogene;
DE   AltName: Full=Oncogene GLI;
GN   Name=GLI1; Synonyms=GLI;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0021696; P:cerebellar cortex morphogenesis; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060032; P:notochord regression; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0007418; P:ventral midline development; IEA:Ensembl.
//
ID   GLI2_HUMAN              Reviewed;        1586 AA.
AC   P10070; O60252; O60253; O60254; O60255; Q15590; Q15591; Q4JHT4;
DE   RecName: Full=Zinc finger protein GLI2;
DE   AltName: Full=Tax helper protein;
GN   Name=GLI2; Synonyms=THP;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0021696; P:cerebellar cortex morphogenesis; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; ISS:UniProtKB.
DR   GO; GO:0048566; P:embryonic digestive tract development; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.
DR   GO; GO:0021508; P:floor plate formation; ISS:UniProtKB.
DR   GO; GO:0060322; P:head development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0030902; P:hindbrain development; ISS:UniProtKB.
DR   GO; GO:0007442; P:hindgut morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0030324; P:lung development; ISS:UniProtKB.
DR   GO; GO:0030879; P:mammary gland development; ISS:UniProtKB.
DR   GO; GO:0060603; P:mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0048666; P:neuron development; ISS:UniProtKB.
DR   GO; GO:0060032; P:notochord regression; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; ISS:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; ISS:UniProtKB.
DR   GO; GO:0021983; P:pituitary gland development; ISS:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0060513; P:prostatic bud formation; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; ISS:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:GOC.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; ISS:UniProtKB.
DR   GO; GO:0021513; P:spinal cord dorsal/ventral patterning; ISS:UniProtKB.
DR   GO; GO:0021965; P:spinal cord ventral commissure morphogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035295; P:tube development; ISS:UniProtKB.
DR   GO; GO:0007418; P:ventral midline development; ISS:UniProtKB.
DR   GO; GO:0021517; P:ventral spinal cord development; ISS:UniProtKB.
//
ID   GLI3_HUMAN              Reviewed;        1580 AA.
AC   P10071; A4D1W1; O75219; Q17RW4; Q75MT0; Q75MU9; Q9UDT5; Q9UJ39;
DE   RecName: Full=Transcriptional activator GLI3;
DE   AltName: Full=GLI3 form of 190 kDa;
DE            Short=GLI3-190;
DE   AltName: Full=GLI3 full length protein;
DE            Short=GLI3FL;
DE   Contains:
DE     RecName: Full=Transcriptional repressor GLI3R;
DE     AltName: Full=GLI3 C-terminally truncated form;
DE     AltName: Full=GLI3 form of 83 kDa;
DE              Short=GLI3-83;
GN   Name=GLI3;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0060873; P:anterior semicircular canal development; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060840; P:artery development; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0061005; P:cell differentiation involved in kidney development; IEA:Ensembl.
DR   GO; GO:0021801; P:cerebral cortex radial glia guided migration; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0048566; P:embryonic digestive tract development; TAS:BHF-UCL.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0021798; P:forebrain dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0021861; P:forebrain radial glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060364; P:frontal suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007442; P:hindgut morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060366; P:lambdoid suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0022018; P:lateral ganglionic eminence cell proliferation; IEA:Ensembl.
DR   GO; GO:0060875; P:lateral semicircular canal development; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060594; P:mammary gland specification; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0046639; P:negative regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045060; P:negative thymic T cell selection; ISS:BHF-UCL.
DR   GO; GO:0043585; P:nose morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0021631; P:optic nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0060367; P:sagittal suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0070242; P:thymocyte apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   GLI4_HUMAN              Reviewed;         376 AA.
AC   P10075; Q96CK9;
DE   RecName: Full=Zinc finger protein GLI4;
DE   AltName: Full=Krueppel-related zinc finger protein 4;
DE   AltName: Full=Protein HKR4;
GN   Name=GLI4; Synonyms=HKR4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   GLIP1_HUMAN             Reviewed;         266 AA.
AC   P48060; A7YET6; F8VUC2; Q15409; Q969K2;
DE   RecName: Full=Glioma pathogenesis-related protein 1;
DE            Short=GliPR 1;
DE   AltName: Full=Protein RTVP-1;
DE   Flags: Precursor;
GN   Name=GLIPR1; Synonyms=GLIPR, RTVP1;
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLIS1_HUMAN             Reviewed;         620 AA.
AC   Q8NBF1; Q2M3G9; Q8N9V9;
DE   RecName: Full=Zinc finger protein GLIS1;
DE   AltName: Full=GLI-similar 1;
GN   Name=GLIS1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   GLIS2_HUMAN             Reviewed;         524 AA.
AC   Q9BZE0; B3KX84;
DE   RecName: Full=Zinc finger protein GLIS2;
DE   AltName: Full=GLI-similar 2;
DE   AltName: Full=Neuronal Krueppel-like protein;
GN   Name=GLIS2; Synonyms=NKL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
//
ID   GLIS3_HUMAN             Reviewed;         775 AA.
AC   Q8NEA6; B1AL19; Q1PHK5;
DE   RecName: Full=Zinc finger protein GLIS3;
DE   AltName: Full=GLI-similar 3;
DE   AltName: Full=Zinc finger protein 515;
GN   Name=GLIS3; Synonyms=ZNF515;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   GLMN_HUMAN              Reviewed;         594 AA.
AC   Q92990; Q5VVC3; Q9BVE8;
DE   RecName: Full=Glomulin;
DE   AltName: Full=FK506-binding protein-associated protein;
DE            Short=FAP;
DE   AltName: Full=FKBP-associated protein;
GN   Name=GLMN; Synonyms=FAP48, FAP68, VMGLOM;
DR   GO; GO:0005171; F:hepatocyte growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:MGI.
DR   GO; GO:0055105; F:ubiquitin-protein ligase inhibitor activity; IGI:MGI.
DR   GO; GO:0042692; P:muscle cell differentiation; IMP:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IGI:GOC.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IMP:UniProtKB.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0040029; P:regulation of gene expression, epigenetic; IMP:UniProtKB.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.
DR   GO; GO:0001570; P:vasculogenesis; IMP:UniProtKB.
//
ID   GLNA_HUMAN              Reviewed;         373 AA.
AC   P15104; Q499Y9; Q5T9Z1; Q7Z3W4; Q8IZ17;
DE   RecName: Full=Glutamine synthetase;
DE            Short=GS;
DE            EC=6.3.1.2;
DE   AltName: Full=Glutamate decarboxylase;
DE            EC=4.1.1.15;
DE   AltName: Full=Glutamate--ammonia ligase;
GN   Name=GLUL; Synonyms=GLNS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016595; F:glutamate binding; IEA:Ensembl.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004356; F:glutamate-ammonia ligase activity; EXP:Reactome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006538; P:glutamate catabolic process; TAS:BHF-UCL.
DR   GO; GO:0006542; P:glutamine biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0001504; P:neurotransmitter uptake; TAS:Reactome.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GLO2_HUMAN              Reviewed;         308 AA.
AC   Q16775; A8K290; B4DRA7;
DE   RecName: Full=Hydroxyacylglutathione hydrolase, mitochondrial;
DE            EC=3.1.2.6;
DE   AltName: Full=Glyoxalase II;
DE            Short=Glx II;
DE   Flags: Precursor;
GN   Name=HAGH; Synonyms=GLO2, HAGH1;
DR   GO; GO:0004416; F:hydroxyacylglutathione hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.
//
ID   GLOD4_HUMAN             Reviewed;         313 AA.
AC   Q9HC38; D3DTG9; D3DTH1; Q96B89; Q9H3J8; Q9HC37; Q9NVN1;
DE   RecName: Full=Glyoxalase domain-containing protein 4;
GN   Name=GLOD4; Synonyms=C17orf25; ORFNames=CGI-150, My027;
//
ID   GLOD5_HUMAN             Reviewed;         160 AA.
AC   A6NK44;
DE   RecName: Full=Glyoxalase domain-containing protein 5;
GN   Name=GLOD5;
//
ID   GLP1R_HUMAN             Reviewed;         463 AA.
AC   P43220; Q2M229; Q99669;
DE   RecName: Full=Glucagon-like peptide 1 receptor;
DE            Short=GLP-1 receptor;
DE            Short=GLP-1-R;
DE            Short=GLP-1R;
DE   Flags: Precursor;
GN   Name=GLP1R;
DR   GuidetoPHARMACOLOGY; 249; -.
DR   GO; GO:0004967; F:glucagon receptor activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLP2R_HUMAN             Reviewed;         553 AA.
AC   O95838; Q4VAT3;
DE   RecName: Full=Glucagon-like peptide 2 receptor;
DE            Short=GLP-2 receptor;
DE            Short=GLP-2-R;
DE            Short=GLP-2R;
GN   Name=GLP2R;
DR   GuidetoPHARMACOLOGY; 250; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004967; F:glucagon receptor activity; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   GLP3L_HUMAN             Reviewed;         285 AA.
AC   Q9H4A5; B1AN09; Q9NVK0;
DE   RecName: Full=Golgi phosphoprotein 3-like;
DE   AltName: Full=GPP34-related protein;
GN   Name=GOLPH3L; Synonyms=GPP34R;
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
//
ID   GLPA_HUMAN              Reviewed;         150 AA.
AC   P02724; A8K3E6; B8Q182; B8Q185; Q9BS51;
DE   RecName: Full=Glycophorin-A;
DE   AltName: Full=MN sialoglycoprotein;
DE   AltName: Full=PAS-2;
DE   AltName: Full=Sialoglycoprotein alpha;
DE   AltName: CD_antigen=CD235a;
DE   Flags: Precursor;
GN   Name=GYPA; Synonyms=GPA;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:Ensembl.
DR   GO; GO:0047484; P:regulation of response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   GLPB_HUMAN              Reviewed;          91 AA.
AC   P06028; B8Q174; E2QBW7; Q0VAF4; Q58HE9; Q58HF0; Q58HF1; Q9UCH7;
DE   RecName: Full=Glycophorin-B;
DE   AltName: Full=PAS-3;
DE   AltName: Full=SS-active sialoglycoprotein;
DE   AltName: Full=Sialoglycoprotein delta;
DE   AltName: CD_antigen=CD235b;
DE   Flags: Precursor;
GN   Name=GYPB; Synonyms=GPB;
//
ID   GLPC_HUMAN              Reviewed;         128 AA.
AC   P04921; B2R522; Q53SV9; Q92642;
DE   RecName: Full=Glycophorin-C;
DE   AltName: Full=Glycoconnectin;
DE   AltName: Full=Glycophorin-D;
DE            Short=GPD;
DE   AltName: Full=Glycoprotein beta;
DE   AltName: Full=PAS-2';
DE   AltName: Full=Sialoglycoprotein D;
DE   AltName: CD_antigen=CD236;
GN   Name=GYPC; Synonyms=GLPC, GPC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   GLPE_HUMAN              Reviewed;          78 AA.
AC   P15421; D3DNZ5;
DE   RecName: Full=Glycophorin-E;
DE   Flags: Precursor;
GN   Name=GYPE; Synonyms=GPE;
//
ID   GLPK2_HUMAN             Reviewed;         553 AA.
AC   Q14410; A8K876; Q6PD73; Q86XV8;
DE   RecName: Full=Glycerol kinase 2;
DE            Short=GK 2;
DE            Short=Glycerokinase 2;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase 2;
DE   AltName: Full=Glycerol kinase, testis specific 2;
GN   Name=GK2; Synonyms=GKP2, GKTA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004370; F:glycerol kinase activity; NAS:UniProtKB.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
//
ID   GLPK3_HUMAN             Reviewed;         553 AA.
AC   Q14409; Q6NXP9;
DE   RecName: Full=Putative glycerol kinase 3;
DE            Short=GK 3;
DE            Short=Glycerokinase 3;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase 3;
DE   AltName: Full=Glycerol kinase, testis specific 1;
GN   Name=GK3P; Synonyms=GKP3, GKTB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004370; F:glycerol kinase activity; NAS:UniProtKB.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
//
ID   GLPK5_HUMAN             Reviewed;         529 AA.
AC   Q6ZS86; B2R9I2; D3DNG2; Q8N2A7; Q8N5E6;
DE   RecName: Full=Putative glycerol kinase 5;
DE            Short=GK 5;
DE            Short=Glycerokinase 5;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase 5;
GN   Name=GK5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
//
ID   GLPK_HUMAN              Reviewed;         559 AA.
AC   P32189; A6NJP5; B2R833; Q6IQ27; Q8IVR5; Q9UMP0; Q9UMP1;
DE   RecName: Full=Glycerol kinase;
DE            Short=GK;
DE            Short=Glycerokinase;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase;
GN   Name=GK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004370; F:glycerol kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006071; P:glycerol metabolic process; IMP:BHF-UCL.
DR   GO; GO:0046167; P:glycerol-3-phosphate biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IMP:BHF-UCL.
//
ID   GLPT_HUMAN              Reviewed;         533 AA.
AC   P57057; D3DSJ7; Q9HAQ1;
DE   RecName: Full=Glycerol-3-phosphate transporter;
DE            Short=G-3-P transporter;
DE   AltName: Full=Glycerol-3-phosphate permease;
DE            Short=G-3-P permease;
DE   AltName: Full=Solute carrier family 37 member 1;
GN   Name=SLC37A1; Synonyms=G3PP;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   GLRA1_HUMAN             Reviewed;         457 AA.
AC   P23415; B2R6T3; Q14C77; Q6DJV9;
DE   RecName: Full=Glycine receptor subunit alpha-1;
DE   AltName: Full=Glycine receptor 48 kDa subunit;
DE   AltName: Full=Glycine receptor strychnine-binding subunit;
DE   Flags: Precursor;
GN   Name=GLRA1;
DR   GuidetoPHARMACOLOGY; 423; -.
DR   GO; GO:0016934; F:extracellular-glycine-gated chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0016594; F:glycine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030977; F:taurine binding; IDA:UniProtKB.
DR   GO; GO:0022824; F:transmitter-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0001508; P:action potential; IEA:Ensembl.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; IDA:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; IMP:UniProtKB.
DR   GO; GO:0051970; P:negative regulation of transmission of nerve impulse; IMP:UniProtKB.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000344; P:positive regulation of acrosome reaction; IMP:UniProtKB.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:MGI.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0060013; P:righting reflex; IEA:Ensembl.
DR   GO; GO:0001964; P:startle response; IMP:UniProtKB.
DR   GO; GO:0060012; P:synaptic transmission, glycinergic; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   GLRA2_HUMAN             Reviewed;         452 AA.
AC   P23416; A8K0J6; B2R6I8; B7Z4F5; J3KQ59; Q53YX7; Q6ICQ0; Q99862;
DE   RecName: Full=Glycine receptor subunit alpha-2;
DE   Flags: Precursor;
GN   Name=GLRA2;
DR   GuidetoPHARMACOLOGY; 424; -.
DR   GO; GO:0016934; F:extracellular-glycine-gated chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0016594; F:glycine binding; IDA:UniProtKB.
DR   GO; GO:0022824; F:transmitter-gated ion channel activity; IEA:InterPro.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GLRA3_HUMAN             Reviewed;         464 AA.
AC   O75311; D3DP44; O75816; Q5D0E3;
DE   RecName: Full=Glycine receptor subunit alpha-3;
DE   Flags: Precursor;
GN   Name=GLRA3;
DR   GuidetoPHARMACOLOGY; 425; -.
DR   GO; GO:0016934; F:extracellular-glycine-gated chloride channel activity; IEA:InterPro.
DR   GO; GO:0016594; F:glycine binding; IEA:InterPro.
DR   GO; GO:0022824; F:transmitter-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GLRA4_HUMAN             Reviewed;         417 AA.
AC   Q5JXX5;
DE   RecName: Full=Glycine receptor subunit alpha-4;
DE   Flags: Precursor;
GN   Name=GLRA4;
DR   GuidetoPHARMACOLOGY; 426; -.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0016594; F:glycine binding; IEA:InterPro.
DR   GO; GO:0022824; F:transmitter-gated ion channel activity; IEA:InterPro.
//
ID   GLRB_HUMAN              Reviewed;         497 AA.
AC   P48167; A8K3K2; D3DP23; F5GWE1;
DE   RecName: Full=Glycine receptor subunit beta;
DE   AltName: Full=Glycine receptor 58 kDa subunit;
DE   Flags: Precursor;
GN   Name=GLRB;
DR   GuidetoPHARMACOLOGY; 427; -.
DR   GO; GO:0016934; F:extracellular-glycine-gated chloride channel activity; TAS:Reactome.
DR   GO; GO:0016933; F:extracellular-glycine-gated ion channel activity; IMP:UniProtKB.
DR   GO; GO:0016594; F:glycine binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0060013; P:righting reflex; IEA:Ensembl.
DR   GO; GO:0001964; P:startle response; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; IMP:UniProtKB.
DR   GO; GO:0060012; P:synaptic transmission, glycinergic; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   GLRX1_HUMAN             Reviewed;         106 AA.
AC   P35754; B2R4L2; Q3KQS1; Q6ICT1;
DE   RecName: Full=Glutaredoxin-1;
DE   AltName: Full=Thioltransferase-1;
DE            Short=TTase-1;
GN   Name=GLRX; Synonyms=GRX;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0015038; F:glutathione disulfide oxidoreductase activity; TAS:ProtInc.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLRX2_HUMAN             Reviewed;         164 AA.
AC   Q9NS18; Q3LR69; Q7L1N7; Q96JC0; Q9Y3D4;
DE   RecName: Full=Glutaredoxin-2, mitochondrial;
DE   Flags: Precursor;
GN   Name=GLRX2; Synonyms=GRX2; ORFNames=CGI-133;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0008794; F:arsenate reductase (glutaredoxin) activity; TAS:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0015038; F:glutathione disulfide oxidoreductase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; TAS:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; TAS:UniProtKB.
DR   GO; GO:0042262; P:DNA protection; NAS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; TAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:GOC.
DR   GO; GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IDA:UniProtKB.
DR   GO; GO:0051775; P:response to redox state; TAS:UniProtKB.
DR   GO; GO:0009266; P:response to temperature stimulus; NAS:UniProtKB.
//
ID   GLRX3_HUMAN             Reviewed;         335 AA.
AC   O76003; B3KMP7; B3KMQ5; D3DRG2; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1;
DE   RecName: Full=Glutaredoxin-3;
DE   AltName: Full=PKC-interacting cousin of thioredoxin;
DE            Short=PICOT;
DE   AltName: Full=PKC-theta-interacting protein;
DE            Short=PKCq-interacting protein;
DE   AltName: Full=Thioredoxin-like protein 2;
GN   Name=GLRX3; Synonyms=PICOT, TXNL2; ORFNames=HUSSY-22;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
//
ID   GLRX5_HUMAN             Reviewed;         157 AA.
AC   Q86SX6; Q0X088; Q3YML0; Q86WY3; Q8IZ54;
DE   RecName: Full=Glutaredoxin-related protein 5, mitochondrial;
DE   AltName: Full=Monothiol glutaredoxin-5;
DE   Flags: Precursor;
GN   Name=GLRX5; Synonyms=C14orf87;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
//
ID   GLR_HUMAN               Reviewed;         477 AA.
AC   P47871; Q2M3M5;
DE   RecName: Full=Glucagon receptor;
DE            Short=GL-R;
DE   Flags: Precursor;
GN   Name=GCGR;
DR   GuidetoPHARMACOLOGY; 251; -.
DR   GO; GO:0004967; F:glucagon receptor activity; IDA:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; IDA:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
DR   GO; GO:0070873; P:regulation of glycogen metabolic process; ISS:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0042594; P:response to starvation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLSK_HUMAN              Reviewed;         669 AA.
AC   O94925; Q9UL05; Q9UL06; Q9UL07; Q9UN40;
DE   RecName: Full=Glutaminase kidney isoform, mitochondrial;
DE            Short=GLS;
DE            EC=3.5.1.2;
DE   AltName: Full=K-glutaminase;
DE   AltName: Full=L-glutamine amidohydrolase;
DE   Flags: Precursor;
GN   Name=GLS; Synonyms=GLS1, KIAA0838;
DR   GO; GO:0004359; F:glutaminase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006543; P:glutamine catabolic process; IDA:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GLSL_HUMAN              Reviewed;         602 AA.
AC   Q9UI32; Q8IX91; Q9NYY2; Q9UI31;
DE   RecName: Full=Glutaminase liver isoform, mitochondrial;
DE            Short=GLS;
DE            EC=3.5.1.2;
DE   AltName: Full=L-glutaminase;
DE   AltName: Full=L-glutamine amidohydrolase;
DE   Flags: Precursor;
GN   Name=GLS2; Synonyms=GA;
DR   GO; GO:0004359; F:glutaminase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:MGI.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GLT10_HUMAN             Reviewed;         603 AA.
AC   Q86SR1; B3KXC9; Q6IN56; Q86VP8; Q8IXJ2; Q8TEJ2; Q96IV2; Q9H8E1;
AC   Q9Y4M4;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 10;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 10;
DE            Short=GalNAc-T10;
DE            Short=pp-GaNTase 10;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 10;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10;
GN   Name=GALNT10;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GLT11_HUMAN             Reviewed;         608 AA.
AC   Q8NCW6; B3KWF4; Q6PCD1; Q9H6C2; Q9H6Z5; Q9UDR8;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 11;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 11;
DE            Short=GalNAc-T11;
DE            Short=pp-GaNTase 11;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 11;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11;
GN   Name=GALNT11;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005112; F:Notch binding; IDA:UniProtKB.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; ISS:UniProtKB.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; ISS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018243; P:protein O-linked glycosylation via threonine; IDA:UniProtKB.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; ISS:UniProtKB.
//
ID   GLT12_HUMAN             Reviewed;         581 AA.
AC   Q8IXK2; Q5TCF7; Q8NG54; Q96CT9; Q9H771;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 12;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 12;
DE            Short=GalNAc-T12;
DE            Short=pp-GaNTase 12;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 12;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12;
GN   Name=GALNT12;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GLT13_HUMAN             Reviewed;         556 AA.
AC   Q8IUC8; Q08ER7; Q6ZWG1; Q96PX0; Q9UIE5;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 13;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 13;
DE            Short=GalNAc-T13;
DE            Short=pp-GaNTase 13;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 13;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13;
GN   Name=GALNT13; Synonyms=KIAA1918;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GLT14_HUMAN             Reviewed;         552 AA.
AC   Q96FL9; B3KV89; Q4ZG75; Q53SU1; Q53TJ0; Q8IVI4; Q9BRH1; Q9H827;
AC   Q9H9J8;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 14;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 14;
DE            Short=GalNAc-T14;
DE            Short=pp-GaNTase 14;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 14;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14;
GN   Name=GALNT14; ORFNames=UNQ2434/PRO4994;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GLT15_HUMAN             Reviewed;         639 AA.
AC   Q8N3T1; A6NMN1; B2R638; F1LIP6; Q86T60; Q96C46; Q96DJ5;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 15;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase-like protein 2;
DE            Short=GalNAc-T-like protein 2;
DE            Short=pp-GaNTase-like protein 2;
DE   AltName: Full=Polypeptide N-acetylgalactosaminyltransferase-like protein 2;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase-like protein 2;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2;
GN   Name=GALNT15; Synonyms=GALNTL2; ORFNames=UNQ770/PRO1564;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   GLT16_HUMAN             Reviewed;         558 AA.
AC   Q8N428; Q4KMG3; Q58A55; Q9ULT9;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 16;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 16;
DE            Short=GalNAc-T16;
DE   AltName: Full=Polypeptide GalNAc transferase-like protein 1;
DE            Short=GalNAc-T-like protein 1;
DE            Short=pp-GaNTase-like protein 1;
DE   AltName: Full=Polypeptide N-acetylgalactosaminyltransferase-like protein 1;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase-like protein 1;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1;
GN   Name=GALNT16; Synonyms=GALNTL1, KIAA1130;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GLT18_HUMAN             Reviewed;         607 AA.
AC   Q6P9A2; O95903; Q8NDY9;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 18;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 18;
DE            Short=GalNAc-T18;
DE   AltName: Full=Polypeptide GalNAc transferase-like protein 4;
DE            Short=GalNAc-T-like protein 4;
DE            Short=pp-GaNTase-like protein 4;
DE   AltName: Full=Polypeptide N-acetylgalactosaminyltransferase-like protein 4;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase-like protein 4;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4;
GN   Name=GALNT18; Synonyms=GALNTL4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GLTD2_HUMAN             Reviewed;         291 AA.
AC   A6NH11; A7E2T2;
DE   RecName: Full=Glycolipid transfer protein domain-containing protein 2;
GN   Name=GLTPD2;
DR   GO; GO:0051861; F:glycolipid binding; IEA:InterPro.
DR   GO; GO:0017089; F:glycolipid transporter activity; IEA:InterPro.
//
ID   GLTL3_HUMAN             Reviewed;         598 AA.
AC   Q6IS24; Q8NFV9; Q9NTA8;
DE   RecName: Full=Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase-like protein 3;
DE            Short=GalNAc-T-like protein 3;
DE            Short=pp-GaNTase-like protein 3;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase-like protein 3;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 17 protein;
GN   Name=WBSCR17; Synonyms=GALNTL3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GLTL5_HUMAN             Reviewed;         443 AA.
AC   Q7Z4T8; Q75KN2; Q75MD3; Q8NCV4; Q8WW05; Q9UDR9;
DE   RecName: Full=Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5;
DE   AltName: Full=Polypeptide GalNAc transferase 15;
DE            Short=GalNAc-T15;
DE            Short=pp-GaNTase 15;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 15;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 15;
GN   Name=GALNTL5; Synonyms=GALNT15;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IMP:UniProtKB.
//
ID   GLTL6_HUMAN             Reviewed;         601 AA.
AC   Q49A17; Q2L4S6;
DE   RecName: Full=Polypeptide N-acetylgalactosaminyltransferase-like 6;
DE            EC=2.4.1.41;
DE   AltName: Full=Polypeptide GalNAc transferase 17;
DE            Short=GalNAc-T17;
DE            Short=pp-GaNTase 17;
DE   AltName: Full=Protein-UDP acetylgalactosaminyltransferase 17;
DE   AltName: Full=Putative polypeptide N-acetylgalactosaminyltransferase 17;
DE   AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17;
GN   Name=GALNTL6; Synonyms=GALNT17;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004653; F:polypeptide N-acetylgalactosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GLTP_HUMAN              Reviewed;         209 AA.
AC   Q9NZD2; Q53Z13; Q96J68;
DE   RecName: Full=Glycolipid transfer protein;
DE            Short=GLTP;
GN   Name=GLTP;
DR   GO; GO:0051861; F:glycolipid binding; IDA:HGNC.
DR   GO; GO:0017089; F:glycolipid transporter activity; IDA:HGNC.
DR   GO; GO:0008289; F:lipid binding; IDA:HGNC.
DR   GO; GO:0046836; P:glycolipid transport; IDA:HGNC.
//
ID   GLU2B_HUMAN             Reviewed;         528 AA.
AC   P14314; A8K318; Q96BU9; Q96D06; Q9P0W9;
DE   RecName: Full=Glucosidase 2 subunit beta;
DE   AltName: Full=80K-H protein;
DE   AltName: Full=Glucosidase II subunit beta;
DE   AltName: Full=Protein kinase C substrate 60.1 kDa protein heavy chain;
DE            Short=PKCSH;
DE   Flags: Precursor;
GN   Name=PRKCSH; Synonyms=G19P1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044325; F:ion channel binding; IPI:UniProt.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProt.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006491; P:N-glycan processing; IEA:InterPro.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0072001; P:renal system development; IEA:Ensembl.
//
ID   GLUC_HUMAN              Reviewed;         180 AA.
AC   P01275; A6NN65; Q53TP6;
DE   RecName: Full=Glucagon;
DE   Contains:
DE     RecName: Full=Glicentin;
DE   Contains:
DE     RecName: Full=Glicentin-related polypeptide;
DE              Short=GRPP;
DE   Contains:
DE     RecName: Full=Oxyntomodulin;
DE              Short=OXM;
DE              Short=OXY;
DE   Contains:
DE     RecName: Full=Glucagon;
DE   Contains:
DE     RecName: Full=Glucagon-like peptide 1;
DE              Short=GLP-1;
DE     AltName: Full=Incretin hormone;
DE   Contains:
DE     RecName: Full=Glucagon-like peptide 1(7-37);
DE              Short=GLP-1(7-37);
DE   Contains:
DE     RecName: Full=Glucagon-like peptide 1(7-36);
DE              Short=GLP-1(7-36);
DE   Contains:
DE     RecName: Full=Glucagon-like peptide 2;
DE              Short=GLP-2;
DE   Flags: Precursor;
GN   Name=GCG;
DR   GO; GO:0031769; F:glucagon receptor binding; IBA:RefGenome.
DR   GO; GO:0005179; F:hormone activity; IBA:RefGenome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:1900118; P:negative regulation of execution phase of apoptosis; IEA:Ensembl.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IBA:RefGenome.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0010737; P:protein kinase A signaling; IBA:RefGenome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0042594; P:response to starvation; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLUR_HUMAN              Reviewed;           8 AA.
AC   P02729;
DE   RecName: Full=Urine glycopeptide;
//
ID   GLYAT_HUMAN             Reviewed;         296 AA.
AC   Q6IB77; O14833; Q96QK7;
DE   RecName: Full=Glycine N-acyltransferase;
DE            EC=2.3.1.13;
DE            EC=2.3.1.71;
DE   AltName: Full=Acyl-CoA:glycine N-acyltransferase;
DE            Short=AAc;
DE   AltName: Full=Aralkyl acyl-CoA N-acyltransferase;
DE   AltName: Full=Aralkyl acyl-CoA:amino acid N-acyltransferase;
DE   AltName: Full=Benzoyl-coenzyme A:glycine N-acyltransferase;
DE   AltName: Full=Glycine N-benzoyltransferase;
DE   AltName: Full=HRP-1(CLP);
GN   Name=GLYAT; Synonyms=ACGNAT, CAT, GAT;
DR   GO; GO:0047961; F:glycine N-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047962; F:glycine N-benzoyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; TAS:ProtInc.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; TAS:ProtInc.
DR   GO; GO:0006544; P:glycine metabolic process; ISS:UniProtKB.
DR   GO; GO:0032787; P:monocarboxylic acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GLYC_HUMAN              Reviewed;         483 AA.
AC   P34896; B4DPM9; D3DXD0; Q96HY0; Q9UMD1; Q9UMD2;
DE   RecName: Full=Serine hydroxymethyltransferase, cytosolic;
DE            Short=SHMT;
DE            EC=2.1.2.1;
DE   AltName: Full=Glycine hydroxymethyltransferase;
DE   AltName: Full=Serine methylase;
GN   Name=SHMT1;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008732; F:L-allo-threonine aldolase activity; IEA:Ensembl.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0045329; P:carnitine biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0046655; P:folic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0019264; P:glycine biosynthetic process from serine; IEA:Ensembl.
DR   GO; GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   GLYG2_HUMAN             Reviewed;         501 AA.
AC   O15488; B7WNN6; O15485; O15486; O15487; O15489; O15490;
DE   RecName: Full=Glycogenin-2;
DE            Short=GN-2;
DE            Short=GN2;
DE            EC=2.4.1.186;
GN   Name=GYG2;
DR   GO; GO:0008466; F:glycogenin glucosyltransferase activity; EXP:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLYG_HUMAN              Reviewed;         350 AA.
AC   P46976; D3DNH0; D3DNH1; D3DNH2; Q6FHZ1; Q9UNV0;
DE   RecName: Full=Glycogenin-1;
DE            Short=GN-1;
DE            Short=GN1;
DE            EC=2.4.1.186;
GN   Name=GYG1; Synonyms=GYG;
DR   GO; GO:0005536; F:glucose binding; IEA:Ensembl.
DR   GO; GO:0008466; F:glycogenin glucosyltransferase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GLYL2_HUMAN             Reviewed;         294 AA.
AC   Q8WU03; A5LGC7; Q86WC3; Q96AT2;
DE   RecName: Full=Glycine N-acyltransferase-like protein 2;
DE            EC=2.3.1.13;
DE   AltName: Full=Acyl-CoA:glycine N-acyltransferase-like protein 2;
GN   Name=GLYATL2;
DR   GO; GO:0047961; F:glycine N-acyltransferase activity; IEA:UniProtKB-EC.
//
ID   GLYL1_HUMAN             Reviewed;         302 AA.
AC   Q969I3; A6NDT0; Q7Z510; Q8NAW8;
DE   RecName: Full=Glycine N-acyltransferase-like protein 1;
DE            EC=2.3.1.68;
DE   AltName: Full=Acyl-CoA:glycine N-acyltransferase-like protein 1;
DE   AltName: Full=Glutamine N-acyltransferase;
GN   Name=GLYATL1; Synonyms=GNAT;
DR   GO; GO:0047946; F:glutamine N-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047961; F:glycine N-acyltransferase activity; IEA:InterPro.
//
ID   GLYL3_HUMAN             Reviewed;         288 AA.
AC   Q5SZD4;
DE   RecName: Full=Glycine N-acyltransferase-like protein 3;
DE            EC=2.3.1.-;
GN   Name=GLYATL3; Synonyms=C6orf140;
DR   GO; GO:0047961; F:glycine N-acyltransferase activity; IEA:InterPro.
//
ID   GLYM_HUMAN              Reviewed;         504 AA.
AC   P34897; B7Z9F1; E7EQ19; E7EU43; O00740; Q8N1A5;
DE   RecName: Full=Serine hydroxymethyltransferase, mitochondrial;
DE            Short=SHMT;
DE            EC=2.1.2.1;
DE   AltName: Full=Glycine hydroxymethyltransferase;
DE   AltName: Full=Serine methylase;
DE   Flags: Precursor;
GN   Name=SHMT2;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008732; F:L-allo-threonine aldolase activity; IEA:Ensembl.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019264; P:glycine biosynthetic process from serine; IEA:Ensembl.
DR   GO; GO:0006564; P:L-serine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006730; P:one-carbon metabolic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
//
ID   GLYR1_HUMAN             Reviewed;         553 AA.
AC   Q49A26; B4DL47; C9JJ40; C9JJ60; Q5U632; Q6P1Q2; Q6V3W7; Q9BTI1;
AC   Q9BXK2;
DE   RecName: Full=Putative oxidoreductase GLYR1;
DE            EC=1.-.-.-;
DE   AltName: Full=3-hydroxyisobutyrate dehydrogenase-like protein;
DE   AltName: Full=Cytokine-like nuclear factor N-PAC;
DE   AltName: Full=Glyoxylate reductase 1 homolog;
DE   AltName: Full=Nuclear protein NP60;
DE   AltName: Full=Nuclear protein of 60 kDa;
GN   Name=GLYR1; Synonyms=HIBDL, NP60;
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
//
ID   GMCL1_HUMAN             Reviewed;         515 AA.
AC   Q96IK5; Q9H826; Q9H8V7; Q9H927;
DE   RecName: Full=Germ cell-less protein-like 1;
GN   Name=GMCL1; Synonyms=GCL;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   GMCLL_HUMAN             Reviewed;         526 AA.
AC   Q8NEA9; B2RDW6; Q8TC88; Q8TC89;
DE   RecName: Full=Putative germ cell-less protein-like 1-like;
GN   Name=GMCL1P1; Synonyms=GCL, GMCL1L;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   GMDS_HUMAN              Reviewed;         372 AA.
AC   O60547; E9PI88; O75357; Q5T954; Q6FH09; Q9UGZ3; Q9UJK9;
DE   RecName: Full=GDP-mannose 4,6 dehydratase;
DE            EC=4.2.1.47;
DE   AltName: Full=GDP-D-mannose dehydratase;
DE            Short=GMD;
GN   Name=GMDS;
DR   GO; GO:0008446; F:GDP-mannose 4,6-dehydratase activity; IDA:UniProtKB.
DR   GO; GO:0070401; F:NADP+ binding; IDA:UniProtKB.
DR   GO; GO:0042351; P:'de novo' GDP-L-fucose biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019673; P:GDP-mannose metabolic process; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.
//
ID   GMEB1_HUMAN             Reviewed;         573 AA.
AC   Q9Y692; B1AT48; Q9NWH1; Q9UKD0;
DE   RecName: Full=Glucocorticoid modulatory element-binding protein 1;
DE            Short=GMEB-1;
DE   AltName: Full=DNA-binding protein p96PIF;
DE   AltName: Full=Parvovirus initiation factor p96;
DE            Short=PIF p96;
GN   Name=GMEB1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GMEB2_HUMAN             Reviewed;         530 AA.
AC   Q9UKD1; E1P5J3; Q5TDS0; Q9H431; Q9H4X7; Q9H4X8; Q9UF78; Q9ULF1;
DE   RecName: Full=Glucocorticoid modulatory element-binding protein 2;
DE            Short=GMEB-2;
DE   AltName: Full=DNA-binding protein p79PIF;
DE   AltName: Full=Parvovirus initiation factor p79;
DE            Short=PIF p79;
GN   Name=GMEB2; Synonyms=KIAA1269;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   GMFG_HUMAN              Reviewed;         142 AA.
AC   O60234; Q6IB37;
DE   RecName: Full=Glia maturation factor gamma;
DE            Short=GMF-gamma;
GN   Name=GMFG;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   GMFB_HUMAN              Reviewed;         142 AA.
AC   P60983; B2R499; P17774;
DE   RecName: Full=Glia maturation factor beta;
DE            Short=GMF-beta;
GN   Name=GMFB;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GMIP_HUMAN              Reviewed;         970 AA.
AC   Q9P107; A0AVN9;
DE   RecName: Full=GEM-interacting protein;
DE            Short=GMIP;
GN   Name=GMIP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0034259; P:negative regulation of Rho GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   GML_HUMAN               Reviewed;         158 AA.
AC   Q99445; A0AVF6; O00686; O00731;
DE   RecName: Full=Glycosyl-phosphatidylinositol-anchored molecule-like protein;
DE   Flags: Precursor;
GN   Name=GML; Synonyms=LY6DL;
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   GMPPA_HUMAN             Reviewed;         420 AA.
AC   Q96IJ6; A6NJ74; A8K3Q6; B3KMT4; Q53GI0; Q9NWC3; Q9Y5P5;
DE   RecName: Full=Mannose-1-phosphate guanyltransferase alpha;
DE   AltName: Full=GDP-mannose pyrophosphorylase A;
DE            Short=GMPP-alpha;
DE   AltName: Full=GTP-mannose-1-phosphate guanylyltransferase alpha;
GN   Name=GMPPA;
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   GMPPB_HUMAN             Reviewed;         360 AA.
AC   Q9Y5P6; A8K6N5; Q9H7U3;
DE   RecName: Full=Mannose-1-phosphate guanyltransferase beta;
DE            EC=2.7.7.13;
DE   AltName: Full=GDP-mannose pyrophosphorylase B;
DE   AltName: Full=GTP-mannose-1-phosphate guanylyltransferase beta;
GN   Name=GMPPB;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   GMPR1_HUMAN             Reviewed;         345 AA.
AC   P36959; Q96HQ6;
DE   RecName: Full=GMP reductase 1;
DE            EC=1.7.1.7;
DE   AltName: Full=Guanosine 5'-monophosphate oxidoreductase 1;
DE            Short=Guanosine monophosphate reductase 1;
GN   Name=GMPR; Synonyms=GMPR1;
DR   GO; GO:0003920; F:GMP reductase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:InterPro.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0009409; P:response to cold; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GMPR2_HUMAN             Reviewed;         348 AA.
AC   Q9P2T1; D3DS66; Q567T0; Q6IAJ8; Q86T14;
DE   RecName: Full=GMP reductase 2;
DE            EC=1.7.1.7;
DE   AltName: Full=Guanosine 5'-monophosphate oxidoreductase 2;
DE            Short=Guanosine monophosphate reductase 2;
GN   Name=GMPR2;
DR   GO; GO:0003920; F:GMP reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046037; P:GMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:InterPro.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GNA11_HUMAN             Reviewed;         359 AA.
AC   P29992; O15109; Q14350; Q6IB00;
DE   RecName: Full=Guanine nucleotide-binding protein subunit alpha-11;
DE            Short=G alpha-11;
DE            Short=G-protein subunit alpha-11;
DE   AltName: Full=Guanine nucleotide-binding protein G(y) subunit alpha;
GN   Name=GNA11; Synonyms=GA11;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0001508; P:action potential; IBA:RefGenome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045634; P:regulation of melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   GNA12_HUMAN             Reviewed;         381 AA.
AC   Q03113; A4D204; Q2T9L1; Q86UM8; Q8TD71; Q9UDU9;
DE   RecName: Full=Guanine nucleotide-binding protein subunit alpha-12;
DE            Short=G alpha-12;
DE            Short=G-protein subunit alpha-12;
GN   Name=GNA12;
DR   GO; GO:0031752; F:D5 dopamine receptor binding; IBA:RefGenome.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0010762; P:regulation of fibroblast migration; ISS:UniProtKB.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0032006; P:regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IBA:RefGenome.
//
ID   GNA13_HUMAN             Reviewed;         377 AA.
AC   Q14344; B2R977; Q8TD70;
DE   RecName: Full=Guanine nucleotide-binding protein subunit alpha-13;
DE            Short=G alpha-13;
DE            Short=G-protein subunit alpha-13;
GN   Name=GNA13;
DR   GO; GO:0031752; F:D5 dopamine receptor binding; IBA:RefGenome.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0031702; F:type 1 angiotensin receptor binding; IBA:RefGenome.
DR   GO; GO:0031584; P:activation of phospholipase D activity; IBA:RefGenome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GNA14_HUMAN             Reviewed;         355 AA.
AC   O95837;
DE   RecName: Full=Guanine nucleotide-binding protein subunit alpha-14;
DE            Short=G alpha-14;
DE            Short=G-protein subunit alpha-14;
GN   Name=GNA14;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GNA15_HUMAN             Reviewed;         374 AA.
AC   P30679; E9KL40; E9KL47; O75247; Q53XK2;
DE   RecName: Full=Guanine nucleotide-binding protein subunit alpha-15;
DE            Short=G alpha-15;
DE            Short=G-protein subunit alpha-15;
DE   AltName: Full=Epididymis tissue protein Li 17E;
DE   AltName: Full=Guanine nucleotide-binding protein subunit alpha-16;
DE            Short=G alpha-16;
DE            Short=G-protein subunit alpha-16;
GN   Name=GNA15; Synonyms=GNA16;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IGI:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007207; P:phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IGI:UniProtKB.
//
ID   GNA1_HUMAN              Reviewed;         184 AA.
AC   Q96EK6;
DE   RecName: Full=Glucosamine 6-phosphate N-acetyltransferase;
DE            EC=2.3.1.4;
DE   AltName: Full=Phosphoglucosamine acetylase;
DE   AltName: Full=Phosphoglucosamine transacetylase;
GN   Name=GNPNAT1; Synonyms=GNA1;
DR   GO; GO:0004343; F:glucosamine 6-phosphate N-acetyltransferase activity; TAS:Reactome.
DR   GO; GO:0048029; F:monosaccharide binding; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006041; P:glucosamine metabolic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; TAS:Reactome.
//
ID   GNAI1_HUMAN             Reviewed;         354 AA.
AC   P63096; A8KA88; B4E2V1; C9J3A4; P04898; P11015; P31871; Q5U074;
AC   Q8TAN5; Q9UGA4;
DE   RecName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-1;
DE   AltName: Full=Adenylate cyclase-inhibiting G alpha protein;
GN   Name=GNAI1;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0031821; F:G-protein coupled serotonin receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; ISS:BHF-UCL.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GNAI2_HUMAN             Reviewed;         355 AA.
AC   P04899; B3KTZ0; B4DYA0; B4E2X5; Q6B6N3; Q8IZ71;
DE   RecName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-2;
DE   AltName: Full=Adenylate cyclase-inhibiting G alpha protein;
GN   Name=GNAI2; Synonyms=GNAI2B;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0001973; P:adenosine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0050805; P:negative regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GNAI3_HUMAN             Reviewed;         354 AA.
AC   P08754; P17539;
DE   RecName: Full=Guanine nucleotide-binding protein G(k) subunit alpha;
DE   AltName: Full=G(i) alpha-3;
GN   Name=GNAI3;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0031821; F:G-protein coupled serotonin receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IDA:UniProtKB.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
DR   GO; GO:0006906; P:vesicle fusion; IEA:Ensembl.
//
ID   GNAL_HUMAN              Reviewed;         381 AA.
AC   P38405; B7ZA26; Q86XU3;
DE   RecName: Full=Guanine nucleotide-binding protein G(olf) subunit alpha;
DE   AltName: Full=Adenylate cyclase-stimulating G alpha protein, olfactory type;
GN   Name=GNAL;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GNAO_HUMAN              Reviewed;         354 AA.
AC   P09471; P29777; Q8TD72; Q9UMV4;
DE   RecName: Full=Guanine nucleotide-binding protein G(o) subunit alpha;
GN   Name=GNAO1;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0031821; F:G-protein coupled serotonin receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
//
ID   GNAQ_HUMAN              Reviewed;         359 AA.
AC   P50148; O15108; Q13462; Q6NT27; Q92471; Q9BZB9;
DE   RecName: Full=Guanine nucleotide-binding protein G(q) subunit alpha;
DE   AltName: Full=Guanine nucleotide-binding protein alpha-q;
GN   Name=GNAQ; Synonyms=GAQ;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0001508; P:action potential; IBA:RefGenome.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0016322; P:neuron remodeling; IEA:Ensembl.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IMP:BHF-UCL.
DR   GO; GO:0035412; P:regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0045634; P:regulation of melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   GNAS1_HUMAN             Reviewed;        1037 AA.
AC   Q5JWF2; A2A2S3; E1P5G3; O75684; O75685; Q5JW67; Q5JWF1; Q9NY42;
DE   RecName: Full=Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas;
DE   AltName: Full=Adenylate cyclase-stimulating G alpha protein;
DE   AltName: Full=Extra large alphas protein;
DE            Short=XLalphas;
GN   Name=GNAS; Synonyms=GNAS1;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0035255; F:ionotropic glutamate receptor binding; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0031852; F:mu-type opioid receptor binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0060348; P:bone development; IMP:UniProt.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0050890; P:cognition; IMP:UniProt.
DR   GO; GO:0048589; P:developmental growth; IMP:UniProt.
DR   GO; GO:0006306; P:DNA methylation; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; IEA:Ensembl.
DR   GO; GO:0071514; P:genetic imprinting; IEA:Ensembl.
DR   GO; GO:0060789; P:hair follicle placode formation; IMP:UniProt.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0070527; P:platelet aggregation; IMP:UniProt.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0040032; P:post-embryonic body morphogenesis; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IBA:RefGenome.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
//
ID   GNAS2_HUMAN             Reviewed;         394 AA.
AC   P63092; A6NI00; E1P5G5; P04895; Q12927; Q14433; Q32P26; Q5JWD2;
AC   Q5JWD4; Q5JWD5; Q6NR75; Q6NXS0; Q8TBC0; Q96H70;
DE   RecName: Full=Guanine nucleotide-binding protein G(s) subunit alpha isoforms short;
DE   AltName: Full=Adenylate cyclase-stimulating G alpha protein;
GN   Name=GNAS; Synonyms=GNAS1, GSP;
DR   GO; GO:0004016; F:adenylate cyclase activity; TAS:Reactome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IDA:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:UniProtKB.
DR   GO; GO:0071880; P:adenylate cyclase-activating adrenergic receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060348; P:bone development; IDA:UniProt.
DR   GO; GO:0006171; P:cAMP biosynthetic process; TAS:GOC.
DR   GO; GO:0071870; P:cellular response to catecholamine stimulus; ISS:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.
DR   GO; GO:0050890; P:cognition; IDA:UniProt.
DR   GO; GO:0048589; P:developmental growth; IDA:UniProt.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0060789; P:hair follicle placode formation; IDA:UniProt.
DR   GO; GO:0046907; P:intracellular transport; NAS:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; IDA:UniProt.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007608; P:sensory perception of smell; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   GNAS3_HUMAN             Reviewed;         245 AA.
AC   O95467; B2RB88; E1P5G2; O95417;
DE   RecName: Full=Neuroendocrine secretory protein 55;
DE            Short=NESP55;
DE   Contains:
DE     RecName: Full=LHAL tetrapeptide;
DE   Contains:
DE     RecName: Full=GPIPIRRH peptide;
DE   Flags: Precursor;
GN   Name=GNAS; Synonyms=GNAS1;
DR   GO; GO:0007565; P:female pregnancy; NAS:UniProtKB.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; ISS:UniProt.
DR   GO; GO:0009306; P:protein secretion; NAS:UniProtKB.
DR   GO; GO:0071107; P:response to parathyroid hormone; IMP:UniProt.
//
ID   GNAT1_HUMAN             Reviewed;         350 AA.
AC   P11488; Q4VBN2;
DE   RecName: Full=Guanine nucleotide-binding protein G(t) subunit alpha-1;
DE   AltName: Full=Transducin alpha-1 chain;
GN   Name=GNAT1; Synonyms=GNATR;
DR   GO; GO:0000035; F:acyl binding; ISS:UniProtKB.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0019003; F:GDP binding; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; ISS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IBA:RefGenome.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProtKB.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; ISS:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; IMP:UniProtKB.
DR   GO; GO:0051343; P:positive regulation of cyclic-nucleotide phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0009642; P:response to light intensity; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; ISS:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0050917; P:sensory perception of umami taste; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:UniProtKB.
//
ID   GNAT2_HUMAN             Reviewed;         354 AA.
AC   P19087;
DE   RecName: Full=Guanine nucleotide-binding protein G(t) subunit alpha-2;
DE   AltName: Full=Transducin alpha-2 chain;
GN   Name=GNAT2; Synonyms=GNATC;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0008020; F:G-protein coupled photoreceptor activity; NAS:UniProtKB.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IBA:RefGenome.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007602; P:phototransduction; NAS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0009642; P:response to light intensity; IEA:Ensembl.
DR   GO; GO:0046549; P:retinal cone cell development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; NAS:UniProtKB.
//
ID   GNAZ_HUMAN              Reviewed;         355 AA.
AC   P19086; B2R6C1; Q4QRJ6;
DE   RecName: Full=Guanine nucleotide-binding protein G(z) subunit alpha;
DE   AltName: Full=G(x) alpha chain;
DE   AltName: Full=Gz-alpha;
GN   Name=GNAZ;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0031821; F:G-protein coupled serotonin receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
//
ID   GNB1L_HUMAN             Reviewed;         327 AA.
AC   Q9BYB4; Q9H2S2; Q9H4M4;
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-like protein 1;
DE            Short=G protein subunit beta-like protein 1;
DE   AltName: Full=DGCRK3;
DE   AltName: Full=WD repeat-containing protein 14;
DE   AltName: Full=WD40 repeat-containing protein deleted in VCFS;
DE            Short=WDVCF;
GN   Name=GNB1L; Synonyms=GY2, KIAA1645, WDR14; ORFNames=FKSG1;
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
//
ID   GNDS_HUMAN              Reviewed;         914 AA.
AC   Q12967; Q5T7V4; Q6KH11; Q9HAX7; Q9HAY1; Q9HCT1; Q9P2N8;
DE   RecName: Full=Ral guanine nucleotide dissociation stimulator;
DE            Short=RalGDS;
DE   AltName: Full=Ral guanine nucleotide exchange factor;
DE            Short=RalGEF;
GN   Name=RALGDS; Synonyms=KIAA1308, RGF;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005083; F:small GTPase regulator activity; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   GNAT3_HUMAN             Reviewed;         354 AA.
AC   A8MTJ3; A4D1B2; A4D1B3; B9EJG5;
DE   RecName: Full=Guanine nucleotide-binding protein G(t) subunit alpha-3;
DE   AltName: Full=Gustducin alpha-3 chain;
GN   Name=GNAT3;
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:RefGenome.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IBA:RefGenome.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IBA:RefGenome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IBA:RefGenome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IBA:RefGenome.
DR   GO; GO:0050917; P:sensory perception of umami taste; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GNL1_HUMAN              Reviewed;         607 AA.
AC   P36915; B0S838; Q96CT5;
DE   RecName: Full=Guanine nucleotide-binding protein-like 1;
DE   AltName: Full=GTP-binding protein HSR1;
GN   Name=GNL1; Synonyms=HSR1;
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IBA:GOC.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0002456; P:T cell mediated immunity; NAS:UniProtKB.
//
ID   GNLY_HUMAN              Reviewed;         145 AA.
AC   P22749; P09325; Q6GU08;
DE   RecName: Full=Granulysin;
DE   AltName: Full=Lymphokine LAG-2;
DE   AltName: Full=Protein NKG5;
DE   AltName: Full=T-cell activation protein 519;
DE   Flags: Precursor;
GN   Name=GNLY; Synonyms=LAG2, NKG5, TLA519;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   GNMT_HUMAN              Reviewed;         295 AA.
AC   Q14749; Q5T8W2; Q9NNZ1; Q9NS24;
DE   RecName: Full=Glycine N-methyltransferase;
DE            EC=2.1.1.20;
GN   Name=GNMT;
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016594; F:glycine binding; IDA:UniProtKB.
DR   GO; GO:0017174; F:glycine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:Ensembl.
DR   GO; GO:0006555; P:methionine metabolic process; IEA:Ensembl.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0046500; P:S-adenosylmethionine metabolic process; IDA:UniProtKB.
//
ID   GNL3_HUMAN              Reviewed;         549 AA.
AC   Q9BVP2; B2RDC1; Q5PU80; Q96SV6; Q96SV7; Q9UJY0;
DE   RecName: Full=Guanine nucleotide-binding protein-like 3;
DE   AltName: Full=E2-induced gene 3 protein;
DE   AltName: Full=Novel nucleolar protein 47;
DE            Short=NNP47;
DE   AltName: Full=Nucleolar GTP-binding protein 3;
DE   AltName: Full=Nucleostemin;
GN   Name=GNL3; Synonyms=E2IG3, NS;
DR   GO; GO:0005525; F:GTP binding; ISS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; IBA:GOC.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
//
ID   GNL3L_HUMAN             Reviewed;         582 AA.
AC   Q9NVN8;
DE   RecName: Full=Guanine nucleotide-binding protein-like 3-like protein;
GN   Name=GNL3L;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006184; P:GTP catabolic process; IBA:GOC.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
//
ID   GNN_HUMAN               Reviewed;        1318 AA.
AC   Q6P2S7; Q05DD4;
DE   RecName: Full=Tetratricopeptide repeat protein GNN;
DE            Short=TPR repeat protein GNN;
DE   AltName: Full=Grp94-neighboring nucleotidase;
GN   Name=GNN;
//
ID   GNPAT_HUMAN             Reviewed;         680 AA.
AC   O15228; Q5TBH7; Q9BWC2;
DE   RecName: Full=Dihydroxyacetone phosphate acyltransferase;
DE            Short=DAP-AT;
DE            Short=DHAP-AT;
DE            EC=2.3.1.42;
DE   AltName: Full=Acyl-CoA:dihydroxyacetonephosphateacyltransferase;
DE   AltName: Full=Glycerone-phosphate O-acyltransferase;
GN   Name=GNPAT; Synonyms=DAPAT, DHAPAT;
DR   GO; GO:0016287; F:glycerone-phosphate O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0021587; P:cerebellum morphogenesis; IEA:Ensembl.
DR   GO; GO:0008611; P:ether lipid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0030913; P:paranodal junction assembly; IEA:Ensembl.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
//
ID   GNPI1_HUMAN             Reviewed;         289 AA.
AC   P46926; D3DQE7;
DE   RecName: Full=Glucosamine-6-phosphate isomerase 1;
DE            EC=3.5.99.6;
DE   AltName: Full=Glucosamine-6-phosphate deaminase 1;
DE            Short=GNPDA 1;
DE            Short=GlcN6P deaminase 1;
DE   AltName: Full=Oscillin;
GN   Name=GNPDA1; Synonyms=GNPI, HLN, KIAA0060;
DR   GO; GO:0004342; F:glucosamine-6-phosphate deaminase activity; IMP:UniProtKB.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IMP:UniProtKB.
DR   GO; GO:0006043; P:glucosamine catabolic process; IMP:UniProtKB.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   GNPI2_HUMAN             Reviewed;         276 AA.
AC   Q8TDQ7; B4DJF3; Q2VYF1; Q59EA7; Q8NCZ8; Q96BJ4; Q96NC6;
DE   RecName: Full=Glucosamine-6-phosphate isomerase 2;
DE            EC=3.5.99.6;
DE   AltName: Full=Glucosamine-6-phosphate deaminase 2;
DE            Short=GNPDA 2;
DE            Short=GlcN6P deaminase 2;
DE   AltName: Full=Glucosamine-6-phosphate isomerase SB52;
GN   Name=GNPDA2; Synonyms=GNP2;
DR   GO; GO:0004342; F:glucosamine-6-phosphate deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro.
//
ID   GNPTA_HUMAN             Reviewed;        1256 AA.
AC   Q3T906; A2RRQ9; Q3ZQK2; Q6IPW5; Q86TQ2; Q96N13; Q9ULL2;
DE   RecName: Full=N-acetylglucosamine-1-phosphotransferase subunits alpha/beta;
DE            EC=2.7.8.17;
DE   AltName: Full=GlcNAc-1-phosphotransferase subunits alpha/beta;
DE   AltName: Full=Stealth protein GNPTAB;
DE   AltName: Full=UDP-N-acetylglucosamine-1-phosphotransferase subunits alpha/beta;
DE   Contains:
DE     RecName: Full=N-acetylglucosamine-1-phosphotransferase subunit alpha;
DE   Contains:
DE     RecName: Full=N-acetylglucosamine-1-phosphotransferase subunit beta;
DE   Flags: Precursor;
GN   Name=GNPTAB; Synonyms=GNPTA, KIAA1208;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003976; F:UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; IDA:UniProtKB.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:InterPro.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0009306; P:protein secretion; IEA:Ensembl.
//
ID   GNPTG_HUMAN             Reviewed;         305 AA.
AC   Q9UJJ9; B2R556; Q6XYD7; Q96L13;
DE   RecName: Full=N-acetylglucosamine-1-phosphotransferase subunit gamma;
DE   AltName: Full=GlcNAc-1-phosphotransferase subunit gamma;
DE   AltName: Full=UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma;
DE   Flags: Precursor;
GN   Name=GNPTG; Synonyms=C16orf27, GNPTAG; ORFNames=CAB56184, LP2537;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0016256; P:N-glycan processing to lysosome; IEA:Ensembl.
//
ID   GNRHR_HUMAN             Reviewed;         328 AA.
AC   P30968; O75793; Q14D13; Q92644;
DE   RecName: Full=Gonadotropin-releasing hormone receptor;
DE            Short=GnRH receptor;
DE            Short=GnRH-R;
GN   Name=GNRHR; Synonyms=GRHR;
DR   GuidetoPHARMACOLOGY; 256; -.
DR   GO; GO:0004968; F:gonadotropin-releasing hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0097211; P:cellular response to gonadotropin-releasing hormone; TAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   GNRR2_HUMAN             Reviewed;         292 AA.
AC   Q96P88; E7EN27; Q8TCX8;
DE   RecName: Full=Putative gonadotropin-releasing hormone II receptor;
DE            Short=GnRH II receptor;
DE            Short=GnRH-II-R;
DE   AltName: Full=Type II GnRH receptor;
GN   Name=GNRHR2;
DR   GuidetoPHARMACOLOGY; 257; -.
DR   GO; GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
//
ID   GNS_HUMAN               Reviewed;         552 AA.
AC   P15586; Q53F05;
DE   RecName: Full=N-acetylglucosamine-6-sulfatase;
DE            EC=3.1.6.14;
DE   AltName: Full=Glucosamine-6-sulfatase;
DE            Short=G6S;
DE   Flags: Precursor;
GN   Name=GNS;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IDA:MGI.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:ProtInc.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GNT2B_HUMAN             Reviewed;         400 AA.
AC   Q06430; Q5W0E9;
DE   RecName: Full=N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B;
DE            Short=N-acetylglucosaminyltransferase;
DE            EC=2.4.1.150;
DE   AltName: Full=I-branching enzyme;
DE   AltName: Full=IGNT;
GN   Name=GCNT2; Synonyms=GCNT5, II, NACGT1;
DR   GO; GO:0008109; F:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
//
ID   GNT2A_HUMAN             Reviewed;         402 AA.
AC   Q8N0V5;
DE   RecName: Full=N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A;
DE            Short=N-acetylglucosaminyltransferase;
DE            EC=2.4.1.150;
DE   AltName: Full=I-branching enzyme;
DE   AltName: Full=IGNT;
GN   Name=GCNT2; Synonyms=GCNT5, II, NACGT1;
DR   GO; GO:0008109; F:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; IMP:UniProt.
DR   GO; GO:0036438; P:maintenance of lens transparency; IMP:UniProt.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IMP:UniProt.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProt.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:UniProt.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProt.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IMP:UniProt.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProt.
DR   GO; GO:0010608; P:posttranscriptional regulation of gene expression; IMP:UniProt.
DR   GO; GO:0006486; P:protein glycosylation; IMP:UniProt.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProt.
//
ID   GNT2C_HUMAN             Reviewed;         402 AA.
AC   Q8NFS9; Q5T4J1; Q6T5E5;
DE   RecName: Full=N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C;
DE            Short=N-acetylglucosaminyltransferase;
DE            EC=2.4.1.150;
DE   AltName: Full=I-branching enzyme;
DE   AltName: Full=IGNT;
GN   Name=GCNT2; Synonyms=GCNT5, II, NACGT1;
DR   GO; GO:0008109; F:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity; IMP:UniProt.
DR   GO; GO:0036438; P:maintenance of lens transparency; IMP:UniProt.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProt.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProt.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:UniProt.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProt.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; ISS:UniProt.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:UniProt.
DR   GO; GO:0010608; P:posttranscriptional regulation of gene expression; ISS:UniProt.
DR   GO; GO:0006486; P:protein glycosylation; IMP:UniProt.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProt.
//
ID   GNTK_HUMAN              Reviewed;         187 AA.
AC   Q5T6J7; A5PLN6; Q5T6J6;
DE   RecName: Full=Probable gluconokinase;
DE            EC=2.7.1.12;
DE   AltName: Full=Gluconate kinase;
GN   Name=IDNK; Synonyms=C9orf103;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046316; F:gluconokinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046177; P:D-gluconate catabolic process; IEA:UniProtKB-UniPathway.
//
ID   GO45_HUMAN              Reviewed;         400 AA.
AC   Q9H2G9; O15298; Q5T531; Q5T533; Q9GZX4;
DE   RecName: Full=Golgin-45;
DE   AltName: Full=Basic leucine zipper nuclear factor 1;
DE   AltName: Full=JEM-1;
DE   AltName: Full=p45 basic leucine-zipper nuclear factor;
GN   Name=BLZF1; Synonyms=JEM1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007030; P:Golgi organization; IDA:MGI.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IDA:MGI.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   GOG6C_HUMAN             Reviewed;         693 AA.
AC   A6NDK9;
DE   RecName: Full=Putative golgin subfamily A member 6C;
GN   Name=GOLGA6C;
//
ID   GOG6A_HUMAN             Reviewed;         693 AA.
AC   Q9NYA3; A8K959; Q9NYA7;
DE   RecName: Full=Golgin subfamily A member 6A;
DE   AltName: Full=Golgin linked to PML;
DE   AltName: Full=Golgin-like protein;
GN   Name=GOLGA6A; Synonyms=GLP, GOLGA6;
//
ID   GOG7B_HUMAN             Reviewed;         167 AA.
AC   Q2TAP0; Q5T4F5;
DE   RecName: Full=Golgin subfamily A member 7B;
GN   Name=GOLGA7B; Synonyms=C10orf132, C10orf133;
//
ID   GOG6D_HUMAN             Reviewed;         693 AA.
AC   P0CG33;
DE   RecName: Full=Putative golgin subfamily A member 6D;
GN   Name=GOLGA6D;
//
ID   GOG6B_HUMAN             Reviewed;         693 AA.
AC   A6NDN3; A8MYY7;
DE   RecName: Full=Putative golgin subfamily A member 6B;
GN   Name=GOLGA6B; Synonyms=GOLGA;
//
ID   GOG8A_HUMAN             Reviewed;         631 AA.
AC   A7E2F4; A7MCY9; B7ZMK5; O94937; Q52M46; Q68DK6; Q9NZG8; Q9NZW0;
AC   Q9NZW3;
DE   RecName: Full=Golgin subfamily A member 8A;
DE   AltName: Full=88 kDa Golgi matrix protein;
DE            Short=GM88;
DE   AltName: Full=GM88 autoantigen;
GN   Name=GOLGA8A;
//
ID   GOG8B_HUMAN             Reviewed;         603 AA.
AC   A8MQT2; A6NLZ2; O94937; Q2M3S9; Q9NZG8; Q9NZW0; Q9NZW3;
DE   RecName: Full=Golgin subfamily A member 8B;
DE   AltName: Full=Golgin-67;
GN   Name=GOLGA8B;
//
ID   GOG8C_HUMAN             Reviewed;         597 AA.
AC   A6NN73;
DE   RecName: Full=Golgin subfamily A member 8C;
GN   Name=GOLGA8CP; Synonyms=GOLGA8C;
//
ID   GOG8D_HUMAN             Reviewed;         430 AA.
AC   Q0D2H9;
DE   RecName: Full=Putative golgin subfamily A member 8D;
GN   Name=GOLGA8DP; Synonyms=GOLGA8D;
//
ID   GOG8H_HUMAN             Reviewed;         632 AA.
AC   P0CJ92;
DE   RecName: Full=Golgin subfamily A member 8H;
GN   Name=GOLGA8H;
//
ID   GOG8I_HUMAN             Reviewed;         632 AA.
AC   A6NC78;
DE   RecName: Full=Golgin subfamily A member 8I;
GN   Name=GOLGA8I; Synonyms=GOLGA8IP;
//
ID   GOG8J_HUMAN             Reviewed;         632 AA.
AC   A6NMD2; H3BRU0;
DE   RecName: Full=Golgin subfamily A member 8J;
GN   Name=GOLGA8J;
//
ID   GOG8K_HUMAN             Reviewed;         607 AA.
AC   D6RF30;
DE   RecName: Full=Golgin subfamily A member 8K;
GN   Name=GOLGA8K;
//
ID   GOG8M_HUMAN             Reviewed;         632 AA.
AC   H3BSY2; A6NCM5; F8WBD5;
DE   RecName: Full=Golgin subfamily A member 8M;
GN   Name=GOLGA8M;
//
ID   GOG8N_HUMAN             Reviewed;         632 AA.
AC   F8WBI6;
DE   RecName: Full=Golgin subfamily A member 8N;
GN   Name=GOLGA8N;
//
ID   GOG8O_HUMAN             Reviewed;         632 AA.
AC   A6NCC3; A6NHZ1; E7ENU5;
DE   RecName: Full=Golgin subfamily A member 8O;
DE   AltName: Full=Golgin subfamily A member 6-like protein 11;
GN   Name=GOLGA8O;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GOG8F_HUMAN             Reviewed;         430 AA.
AC   Q08AF8; A4FTY1; Q1A5X9; Q8NDK0;
DE   RecName: Full=Putative golgin subfamily A member 8F/8G;
GN   Name=GOLGA8F;
GN   and
GN   Name=GOLGA8G;
//
ID   GOG8R_HUMAN             Reviewed;         631 AA.
AC   I6L899; F5GYM5;
DE   RecName: Full=Golgin subfamily A member 8R;
GN   Name=GOLGA8R;
//
ID   GOGA2_HUMAN             Reviewed;        1002 AA.
AC   Q08379; Q6GRM9; Q9BRB0; Q9NYF9;
DE   RecName: Full=Golgin subfamily A member 2;
DE   AltName: Full=130 kDa cis-Golgi matrix protein;
DE            Short=GM130;
DE   AltName: Full=GM130 autoantigen;
DE   AltName: Full=Golgin-95;
GN   Name=GOLGA2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   GOGA1_HUMAN             Reviewed;         767 AA.
AC   Q92805; Q5T164; Q8IYZ9;
DE   RecName: Full=Golgin subfamily A member 1;
DE   AltName: Full=Golgin-97;
GN   Name=GOLGA1;
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   GOGA3_HUMAN             Reviewed;        1498 AA.
AC   Q08378; A5PKX6; O43241; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3;
DE   RecName: Full=Golgin subfamily A member 3;
DE   AltName: Full=Golgi complex-associated protein of 170 kDa;
DE            Short=GCP170;
DE   AltName: Full=Golgin-160;
GN   Name=GOLGA3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; NAS:UniProtKB.
//
ID   GOGA4_HUMAN             Reviewed;        2230 AA.
AC   Q13439; F8W8Q7; Q13270; Q13654; Q14436; Q59EW8;
DE   RecName: Full=Golgin subfamily A member 4;
DE   AltName: Full=256 kDa golgin;
DE   AltName: Full=Golgin-245;
DE   AltName: Full=Protein 72.1;
DE   AltName: Full=Trans-Golgi p230;
GN   Name=GOLGA4;
DR   GO; GO:0051020; F:GTPase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB.
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   GOGA5_HUMAN             Reviewed;         731 AA.
AC   Q8TBA6; C9JRU1; O95287; Q03962; Q2TS49; Q9UQQ7;
DE   RecName: Full=Golgin subfamily A member 5;
DE   AltName: Full=Cell proliferation-inducing gene 31 protein;
DE   AltName: Full=Golgin-84;
DE   AltName: Full=Protein Ret-II;
DE   AltName: Full=RET-fused gene 5 protein;
GN   Name=GOLGA5; Synonyms=RETII, RFG5; ORFNames=PIG31;
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.
//
ID   GOGA7_HUMAN             Reviewed;         137 AA.
AC   Q7Z5G4; D3DSX9; J3KQ24; Q96EQ4; Q9P1S0; Q9Y5U7;
DE   RecName: Full=Golgin subfamily A member 7;
DE   AltName: Full=Golgi complex-associated protein of 16 kDa;
GN   Name=GOLGA7; Synonyms=GCP16; ORFNames=HDCKB03P, HSPC041;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProt.
DR   GO; GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IDA:UniProt.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProt.
//
ID   GOLI4_HUMAN             Reviewed;         696 AA.
AC   O00461;
DE   RecName: Full=Golgi integral membrane protein 4;
DE   AltName: Full=Golgi integral membrane protein, cis;
DE            Short=GIMPc;
DE   AltName: Full=Golgi phosphoprotein 4;
DE   AltName: Full=Golgi-localized phosphoprotein of 130 kDa;
DE            Short=Golgi phosphoprotein of 130 kDa;
GN   Name=GOLIM4; Synonyms=GIMPC, GOLPH4, GPP130;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   GOLI_HUMAN              Reviewed;         419 AA.
AC   Q86XS8; Q32P32; Q641P9; Q6P177; Q7L2U2; Q9P0J9;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF130;
DE            EC=6.3.2.-;
DE   AltName: Full=Goliath homolog;
DE            Short=H-Goliath;
DE   AltName: Full=RING finger protein 130;
DE   Flags: Precursor;
GN   Name=RNF130;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0012501; P:programmed cell death; ISS:UniProtKB.
//
ID   GOLM1_HUMAN             Reviewed;         401 AA.
AC   Q8NBJ4; Q6IAF4; Q9NRB9;
DE   RecName: Full=Golgi membrane protein 1;
DE   AltName: Full=Golgi membrane protein GP73;
DE   AltName: Full=Golgi phosphoprotein 2;
GN   Name=GOLM1; Synonyms=C9orf155, GOLPH2;
GN   ORFNames=PSEC0242, UNQ686/PRO1326;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006997; P:nucleus organization; IEA:Ensembl.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
//
ID   GOLP3_HUMAN             Reviewed;         298 AA.
AC   Q9H4A6; Q9UIW5;
DE   RecName: Full=Golgi phosphoprotein 3;
DE   AltName: Full=Coat protein GPP34;
DE   AltName: Full=Mitochondrial DNA absence factor;
DE            Short=MIDAS;
GN   Name=GOLPH3; Synonyms=GPP34;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060352; P:cell adhesion molecule production; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; IMP:UniProtKB.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.
DR   GO; GO:0048194; P:Golgi vesicle budding; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IMP:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0045053; P:protein retention in Golgi apparatus; IMP:UniProtKB.
DR   GO; GO:0009306; P:protein secretion; IMP:UniProtKB.
DR   GO; GO:0010821; P:regulation of mitochondrion organization; IDA:UniProtKB.
//
ID   GOGB1_HUMAN             Reviewed;        3259 AA.
AC   Q14789; B2ZZ91; D3DN92; E7EP74; Q14398;
DE   RecName: Full=Golgin subfamily B member 1;
DE   AltName: Full=372 kDa Golgi complex-associated protein;
DE            Short=GCP372;
DE   AltName: Full=Giantin;
DE   AltName: Full=Macrogolgin;
GN   Name=GOLGB1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; TAS:ProtInc.
//
ID   GON1_HUMAN              Reviewed;          92 AA.
AC   P01148; A0AVP0;
DE   RecName: Full=Progonadoliberin-1;
DE   AltName: Full=Progonadoliberin I;
DE   Contains:
DE     RecName: Full=Gonadoliberin-1;
DE     AltName: Full=Gonadoliberin I;
DE     AltName: Full=Gonadorelin;
DE     AltName: Full=Gonadotropin-releasing hormone I;
DE              Short=GnRH-I;
DE     AltName: Full=Luliberin I;
DE     AltName: Full=Luteinizing hormone-releasing hormone I;
DE              Short=LH-RH I;
DE   Contains:
DE     RecName: Full=GnRH-associated peptide 1;
DE     AltName: Full=GnRH-associated peptide I;
DE   Flags: Precursor;
GN   Name=GNRH1; Synonyms=GNRH, GRH, LHRH;
DR   GO; GO:0005183; F:gonadotropin hormone-releasing hormone activity; TAS:ProtInc.
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:2001223; P:negative regulation of neuron migration; IEA:Ensembl.
DR   GO; GO:0042698; P:ovulation cycle; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:2000354; P:regulation of ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GON2_HUMAN              Reviewed;         120 AA.
AC   O43555; Q14C68; Q14C69; Q9BYN9; Q9BYP0;
DE   RecName: Full=Progonadoliberin-2;
DE   AltName: Full=Progonadoliberin II;
DE   Contains:
DE     RecName: Full=Gonadoliberin-2;
DE     AltName: Full=Gonadoliberin II;
DE     AltName: Full=Gonadotropin-releasing hormone II;
DE              Short=GnRH II;
DE     AltName: Full=Luliberin II;
DE     AltName: Full=Luteinizing hormone-releasing hormone II;
DE              Short=LH-RH II;
DE   Contains:
DE     RecName: Full=GnRH-associated peptide 2;
DE     AltName: Full=GnRH-associated peptide II;
DE   Flags: Precursor;
GN   Name=GNRH2;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GON4L_HUMAN             Reviewed;        2241 AA.
AC   Q3T8J9; B7ZBL4; Q14C93; Q3T8J8; Q5VYZ5; Q5W0D5; Q6AWA6; Q6P1Q6;
AC   Q7Z3L3; Q8IY79; Q9BQI1; Q9HCG6;
DE   RecName: Full=GON-4-like protein;
DE   AltName: Full=GON-4 homolog;
GN   Name=GON4L; Synonyms=GON4, KIAA1606;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   GOPC_HUMAN              Reviewed;         462 AA.
AC   Q9HD26; A6NM30; Q59FS4; Q969U8;
DE   RecName: Full=Golgi-associated PDZ and coiled-coil motif-containing protein;
DE   AltName: Full=CFTR-associated ligand;
DE   AltName: Full=Fused in glioblastoma;
DE   AltName: Full=PDZ protein interacting specifically with TC10;
DE            Short=PIST;
GN   Name=GOPC; Synonyms=CAL, FIG;
DR   GO; GO:0044325; F:ion channel binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:Ensembl.
DR   GO; GO:0045176; P:apical protein localization; NAS:UniProtKB.
DR   GO; GO:0043004; P:cytoplasmic sequestering of CFTR protein; NAS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; NAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
//
ID   GORAB_HUMAN             Reviewed;         394 AA.
AC   Q5T7V8; Q49A22; Q6P1P9; Q9HAE6; Q9Y350;
DE   RecName: Full=RAB6-interacting golgin;
DE   AltName: Full=N-terminal kinase-like-binding protein 1;
DE            Short=NTKL-BP1;
DE            Short=NTKL-binding protein 1;
DE            Short=hNTKL-BP1;
DE   AltName: Full=SCY1-like 1-binding protein 1;
DE            Short=SCYL1-BP1;
DE            Short=SCYL1-binding protein 1;
GN   Name=GORAB; Synonyms=NTKLBP1, SCYL1BP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   GORS1_HUMAN             Reviewed;         440 AA.
AC   Q9BQQ3; B3KWC8; Q3SYG7; Q8N272; Q96H42;
DE   RecName: Full=Golgi reassembly-stacking protein 1;
DE   AltName: Full=Golgi peripheral membrane protein p65;
DE   AltName: Full=Golgi phosphoprotein 5;
DE            Short=GOLPH5;
DE   AltName: Full=Golgi reassembly-stacking protein of 65 kDa;
DE            Short=GRASP65;
GN   Name=GORASP1; Synonyms=GOLPH5, GRASP65;
DR   GO; GO:0007030; P:Golgi organization; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0050774; P:negative regulation of dendrite morphogenesis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   GORS2_HUMAN             Reviewed;         452 AA.
AC   Q9H8Y8; B4DKT0; Q53TE3; Q96I74; Q96K84; Q9H946; Q9UFW4;
DE   RecName: Full=Golgi reassembly-stacking protein 2;
DE            Short=GRS2;
DE   AltName: Full=Golgi phosphoprotein 6;
DE            Short=GOLPH6;
DE   AltName: Full=Golgi reassembly-stacking protein of 55 kDa;
DE            Short=GRASP55;
DE   AltName: Full=p59;
GN   Name=GORASP2; Synonyms=GOLPH6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006996; P:organelle organization; IMP:UniProtKB.
//
ID   GOR_HUMAN               Reviewed;         675 AA.
AC   Q8IX06; A6NK34; O95107;
DE   RecName: Full=Putative exonuclease GOR;
DE            EC=3.1.-.-;
DE   AltName: Full=Antigen GOR homolog;
DE   AltName: Full=RNA exonuclease 1 homolog-like 1;
GN   Name=REXO1L1P; Synonyms=GOR, REXO1L1;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   GOSR1_HUMAN             Reviewed;         250 AA.
AC   O95249; J3KST5; O75392;
DE   RecName: Full=Golgi SNAP receptor complex member 1;
DE   AltName: Full=28 kDa Golgi SNARE protein;
DE   AltName: Full=28 kDa cis-Golgi SNARE p28;
DE            Short=GOS-28;
GN   Name=GOSR1; Synonyms=GS28;
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:HGNC.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:HGNC.
//
ID   GOSR2_HUMAN             Reviewed;         212 AA.
AC   O14653; D3DXJ5; D3DXJ6; Q8N4B8; Q96DA5; Q9BZZ4;
DE   RecName: Full=Golgi SNAP receptor complex member 2;
DE   AltName: Full=27 kDa Golgi SNARE protein;
DE   AltName: Full=Membrin;
GN   Name=GOSR2; Synonyms=GS27;
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   GOT1A_HUMAN             Reviewed;         132 AA.
AC   Q6ZVE7;
DE   RecName: Full=Vesicle transport protein GOT1A;
DE   AltName: Full=Golgi transport 1 homolog A;
DE   AltName: Full=hGOT1b;
GN   Name=GOLT1A; Synonyms=GOT1B;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   GOT1B_HUMAN             Reviewed;         138 AA.
AC   Q9Y3E0; B2R4R4; Q54A40; Q6I9W6; Q9P1R9;
DE   RecName: Full=Vesicle transport protein GOT1B;
DE   AltName: Full=Germ cell tumor 2;
DE   AltName: Full=Golgi transport 1 homolog B;
DE   AltName: Full=Putative NF-kappa-B-activating protein 470;
DE   AltName: Full=hGOT1a;
GN   Name=GOLT1B; Synonyms=GCT2, GOT1A;
GN   ORFNames=CGI-141, HDCMA39P, UNQ432/PRO793;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   GP101_HUMAN             Reviewed;         508 AA.
AC   Q96P66; Q5JSM8; Q8NG93;
DE   RecName: Full=Probable G-protein coupled receptor 101;
GN   Name=GPR101;
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
//
ID   GP107_HUMAN             Reviewed;         600 AA.
AC   Q5VW38; A6NJ53; Q2TB81; Q5JPA3; Q5VW39; Q96T26; Q9H658; Q9HCE8;
DE   RecName: Full=Protein GPR107;
DE   AltName: Full=Lung seven transmembrane receptor 1;
DE   Flags: Precursor;
GN   Name=GPR107; Synonyms=KIAA1624, LUSTR1;
DR   GuidetoPHARMACOLOGY; 651; -.
//
ID   GP108_HUMAN             Reviewed;         543 AA.
AC   Q9NPR9; B9EJD7;
DE   RecName: Full=Protein GPR108;
DE   AltName: Full=Lung seven transmembrane receptor 2;
DE   Flags: Precursor;
GN   Name=GPR108; Synonyms=LUSTR2;
//
ID   GP110_HUMAN             Reviewed;         910 AA.
AC   Q5T601; Q5KU15; Q5T5Z9; Q5T600; Q86SM1; Q8IXE3; Q8IZF8; Q96DQ1;
AC   Q9H615;
DE   RecName: Full=Probable G-protein coupled receptor 110;
DE   AltName: Full=G-protein coupled receptor KPG_012;
DE   AltName: Full=G-protein coupled receptor PGR19;
DE   Flags: Precursor;
GN   Name=GPR110; Synonyms=PGR19;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP111_HUMAN             Reviewed;         708 AA.
AC   Q8IZF7; Q2PNZ1; Q86SL6; Q8NGU5; Q8TDT5;
DE   RecName: Full=Probable G-protein coupled receptor 111;
DE   AltName: Full=G-protein coupled receptor PGR20;
GN   Name=GPR111; Synonyms=PGR20;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP112_HUMAN             Reviewed;        3080 AA.
AC   Q8IZF6; A2A2J1; A2A2J2; Q5EGP2; Q86SM6;
DE   RecName: Full=Probable G-protein coupled receptor 112;
DE   Flags: Precursor;
GN   Name=GPR112;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP113_HUMAN             Reviewed;        1079 AA.
AC   Q8IZF5; B4DF15; E9PEV1; Q53TA5; Q6UXT7; Q6UXX3; Q86SL7; Q8IXD8;
AC   Q8TDT3;
DE   RecName: Full=Probable G-protein coupled receptor 113;
DE   AltName: Full=G-protein coupled receptor PGR23;
DE   Flags: Precursor;
GN   Name=GPR113; Synonyms=PGR23; ORFNames=UNQ9196/PRO34000;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP114_HUMAN             Reviewed;         528 AA.
AC   Q8IZF4; B3KXZ5; Q6ZMH7; Q6ZML4; Q86SL8; Q8IZ14;
DE   RecName: Full=Probable G-protein coupled receptor 114;
DE   AltName: Full=G-protein coupled receptor PGR27;
DE   Flags: Precursor;
GN   Name=GPR114; Synonyms=PGR27; ORFNames=UNQ2524/PRO6017;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP115_HUMAN             Reviewed;         695 AA.
AC   Q8IZF3; B3KTD0; Q2PNZ0; Q5T5B5; Q5T5B6; Q86SN9; Q8IXE6;
DE   RecName: Full=Probable G-protein coupled receptor 115;
DE   AltName: Full=G-protein coupled receptor PGR18;
DE   Flags: Precursor;
GN   Name=GPR115; Synonyms=PGR18;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP116_HUMAN             Reviewed;        1346 AA.
AC   Q8IZF2; O94858; Q5TF06; Q6RGN2; Q86SP0; Q9Y3Z2;
DE   RecName: Full=Probable G-protein coupled receptor 116;
DE   Flags: Precursor;
GN   Name=GPR116; Synonyms=KIAA0758;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0006112; P:energy reserve metabolic process; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
//
ID   GP119_HUMAN             Reviewed;         335 AA.
AC   Q8TDV5; Q495H7; Q4VBN3;
DE   RecName: Full=Glucose-dependent insulinotropic receptor;
DE   AltName: Full=G-protein coupled receptor 119;
GN   Name=GPR119;
DR   GuidetoPHARMACOLOGY; 126; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
//
ID   GP123_HUMAN             Reviewed;         560 AA.
AC   Q86SQ6; A5HL16; A6NG50; Q5T234; Q86SN7; Q96JJ9;
DE   RecName: Full=Probable G-protein coupled receptor 123;
GN   Name=GPR123; Synonyms=KIAA1828;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   GP124_HUMAN             Reviewed;        1338 AA.
AC   Q96PE1; A6H8W3; D3DSW4; Q8N3R1; Q8TEM3; Q96KB2; Q9P1Z7; Q9UFY4;
DE   RecName: Full=G-protein coupled receptor 124;
DE   AltName: Full=Tumor endothelial marker 5;
DE   Flags: Precursor;
GN   Name=GPR124; Synonyms=KIAA1531, TEM5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:1900747; P:negative regulation of vascular endothelial growth factor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0050920; P:regulation of chemotaxis; ISS:UniProtKB.
DR   GO; GO:0090210; P:regulation of establishment of blood-brain barrier; IEA:Ensembl.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
//
ID   GP125_HUMAN             Reviewed;        1321 AA.
AC   Q8IWK6; Q6UXK9; Q86SQ5; Q8TC55;
DE   RecName: Full=Probable G-protein coupled receptor 125;
DE   Flags: Precursor;
GN   Name=GPR125; ORFNames=UNQ556/PRO1113;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP126_HUMAN             Reviewed;        1221 AA.
AC   Q86SQ4; Q5TGN7; Q6DHZ4; Q6F3F5; Q6F3F6; Q6F3F7; Q6F3F8; Q6MZU7;
AC   Q8IXA4; Q8NC14; Q96JW0;
DE   RecName: Full=G-protein coupled receptor 126;
DE   AltName: Full=Developmentally regulated G-protein-coupled receptor;
DE   AltName: Full=Vascular inducible G protein-coupled receptor;
DE   Flags: Precursor;
GN   Name=GPR126; Synonyms=DREG, VIGR;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP128_HUMAN             Reviewed;         797 AA.
AC   Q96K78; Q14D94; Q86SQ2;
DE   RecName: Full=Probable G-protein coupled receptor 128;
DE   Flags: Precursor;
GN   Name=GPR128;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP132_HUMAN             Reviewed;         380 AA.
AC   Q9UNW8; A8K7X7; B4E144; Q9BSU2;
DE   RecName: Full=Probable G-protein coupled receptor 132;
DE   AltName: Full=G2 accumulation protein;
GN   Name=GPR132; Synonyms=G2A;
DR   GuidetoPHARMACOLOGY; 128; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   GP133_HUMAN             Reviewed;         874 AA.
AC   Q6QNK2; B2CKK9; B7ZLF7; Q2M1L3; Q6ZMQ1; Q7Z7M2; Q86SM4;
DE   RecName: Full=Probable G-protein coupled receptor 133;
DE   AltName: Full=G-protein coupled receptor PGR25;
DE   Flags: Precursor;
GN   Name=GPR133; Synonyms=PGR25;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP135_HUMAN             Reviewed;         494 AA.
AC   Q8IZ08; Q7Z604; Q86SM3; Q8NH39;
DE   RecName: Full=Probable G-protein coupled receptor 135;
GN   Name=GPR135;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP139_HUMAN             Reviewed;         353 AA.
AC   Q6DWJ6; A8K5R9; Q86SP2; Q8TDU8;
DE   RecName: Full=Probable G-protein coupled receptor 139;
DE   AltName: Full=G(q)-coupled orphan receptor GPRg1;
DE   AltName: Full=G-protein-coupled receptor PGR3;
GN   Name=GPR139; Synonyms=GPRG1, PGR3;
DR   GO; GO:0008188; F:neuropeptide receptor activity; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:MGI.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
//
ID   GP141_HUMAN             Reviewed;         305 AA.
AC   Q7Z602; A4D1X7; Q0VAR5; Q86SP3;
DE   RecName: Full=Probable G-protein coupled receptor 141;
DE   AltName: Full=G-protein coupled receptor PGR13;
GN   Name=GPR141; Synonyms=PGR13;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP142_HUMAN             Reviewed;         462 AA.
AC   Q7Z601; A4CYJ8; Q86SL3;
DE   RecName: Full=Probable G-protein coupled receptor 142;
DE   AltName: Full=G-protein coupled receptor PGR2;
GN   Name=GPR142; Synonyms=PGR2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP143_HUMAN             Reviewed;         404 AA.
AC   P51810; Q6NTI7;
DE   RecName: Full=G-protein coupled receptor 143;
DE   AltName: Full=Ocular albinism type 1 protein;
GN   Name=GPR143; Synonyms=OA1;
DR   GuidetoPHARMACOLOGY; 203; -.
DR   GO; GO:0035240; F:dopamine binding; IDA:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0072544; F:L-DOPA binding; IDA:UniProtKB.
DR   GO; GO:0035643; F:L-DOPA receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0072545; F:tyrosine binding; IDA:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IDA:UniProtKB.
DR   GO; GO:0006726; P:eye pigment biosynthetic process; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032400; P:melanosome localization; IDA:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; IMP:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0050848; P:regulation of calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   GP144_HUMAN             Reviewed;         963 AA.
AC   Q7Z7M1; Q86SL4; Q8NH12;
DE   RecName: Full=Probable G-protein coupled receptor 144;
DE   AltName: Full=G-protein coupled receptor PGR24;
GN   Name=GPR144; Synonyms=PGR24;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GP146_HUMAN             Reviewed;         333 AA.
AC   Q96CH1; Q86SP5;
DE   RecName: Full=Probable G-protein coupled receptor 146;
DE   AltName: Full=G-protein coupled receptor PGR8;
GN   Name=GPR146; Synonyms=PGR8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP148_HUMAN             Reviewed;         347 AA.
AC   Q8TDV2; Q2M369; Q86SP7; Q86U87;
DE   RecName: Full=Probable G-protein coupled receptor 148;
DE   AltName: Full=Brain and testis restricted GPCR;
DE   AltName: Full=G-protein coupled receptor PGR6;
GN   Name=GPR148; Synonyms=BTR, PGR6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP149_HUMAN             Reviewed;         731 AA.
AC   Q86SP6;
DE   RecName: Full=Probable G-protein coupled receptor 149;
DE   AltName: Full=G-protein coupled receptor PGR10;
GN   Name=GPR149; Synonyms=PGR10;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001547; P:antral ovarian follicle growth; IEA:Ensembl.
DR   GO; GO:0060206; P:estrous cycle phase; IEA:Ensembl.
DR   GO; GO:0060280; P:negative regulation of ovulation; IEA:Ensembl.
DR   GO; GO:0001546; P:preantral ovarian follicle growth; IEA:Ensembl.
//
ID   GP150_HUMAN             Reviewed;         434 AA.
AC   Q8NGU9;
DE   RecName: Full=Probable G-protein coupled receptor 150;
GN   Name=GPR150;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP151_HUMAN             Reviewed;         419 AA.
AC   Q8TDV0; Q86SN8; Q8NGV2;
DE   RecName: Full=Probable G-protein coupled receptor 151;
DE   AltName: Full=G-protein coupled receptor PGR7;
DE   AltName: Full=GPCR-2037;
GN   Name=GPR151; Synonyms=PGR7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP152_HUMAN             Reviewed;         470 AA.
AC   Q8TDT2; Q0VD88; Q86SM0;
DE   RecName: Full=Probable G-protein coupled receptor 152;
DE   AltName: Full=G-protein coupled receptor PGR5;
GN   Name=GPR152; Synonyms=PGR5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP153_HUMAN             Reviewed;         609 AA.
AC   Q6NV75; Q5TGR5; Q6AHW8; Q86SP8;
DE   RecName: Full=Probable G-protein coupled receptor 153;
DE   AltName: Full=G-protein coupled receptor PGR1;
GN   Name=GPR153; Synonyms=PGR1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP155_HUMAN             Reviewed;         870 AA.
AC   Q7Z3F1; B2RCI2; D3DPE2; Q4G0Y6; Q53SJ3; Q53TA8; Q69YG8; Q86SP9;
AC   Q8N261; Q8N639; Q8N8K3; Q96MV6;
DE   RecName: Full=Integral membrane protein GPR155;
DE   AltName: Full=G-protein coupled receptor PGR22;
GN   Name=GPR155; Synonyms=PGR22;
DR   GO; GO:0050890; P:cognition; IMP:UniProt.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   GP156_HUMAN             Reviewed;         814 AA.
AC   Q8NFN8; B7ZL66; E9PFZ4; Q14CM1; Q86SN6;
DE   RecName: Full=Probable G-protein coupled receptor 156;
DE   AltName: Full=G-protein coupled receptor PGR28;
DE   AltName: Full=GABAB-related G-protein coupled receptor;
GN   Name=GPR156; Synonyms=GABABL, PGR28;
DR   GO; GO:0004965; F:G-protein coupled GABA receptor activity; IEA:InterPro.
//
ID   GP157_HUMAN             Reviewed;         335 AA.
AC   Q5UAW9; A2A334; Q8WWB8; Q9HA73;
DE   RecName: Full=Probable G-protein coupled receptor 157;
GN   Name=GPR157;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP158_HUMAN             Reviewed;        1215 AA.
AC   Q5T848; Q6QR81; Q9ULT3;
DE   RecName: Full=Probable G-protein coupled receptor 158;
DE   Flags: Precursor;
GN   Name=GPR158; Synonyms=KIAA1136;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
//
ID   GP160_HUMAN             Reviewed;         338 AA.
AC   Q9UJ42; D3DNQ2;
DE   RecName: Full=Probable G-protein coupled receptor 160;
DE   AltName: Full=G-protein coupled receptor GPCR1;
DE            Short=hGPCR1;
GN   Name=GPR160; Synonyms=GPCR150;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP161_HUMAN             Reviewed;         529 AA.
AC   Q8N6U8; B3KV34; B7Z5D7; B7Z5E8; B7Z5Z6; F5GXD6; F5H6J7; O75963;
AC   Q5TGK0; Q5TGK1; Q5TGK2;
DE   RecName: Full=G-protein coupled receptor 161;
DE   AltName: Full=G-protein coupled receptor RE2;
GN   Name=GPR161;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:1901621; P:negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; ISS:UniProtKB.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; ISS:UniProtKB.
//
ID   GP162_HUMAN             Reviewed;         588 AA.
AC   Q16538; Q16664; Q59EH5; Q66K56;
DE   RecName: Full=Probable G-protein coupled receptor 162;
DE   AltName: Full=Gene-rich cluster gene A protein;
GN   Name=GPR162; Synonyms=GRCA;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP171_HUMAN             Reviewed;         319 AA.
AC   O14626; D3DNJ4; Q8IV06;
DE   RecName: Full=Probable G-protein coupled receptor 171;
DE   AltName: Full=G-protein coupled receptor H963;
GN   Name=GPR171; Synonyms=H963;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
//
ID   GP173_HUMAN             Reviewed;         373 AA.
AC   Q9NS66; B1B0A5;
DE   RecName: Full=Probable G-protein coupled receptor 173;
DE   AltName: Full=Super conserved receptor expressed in brain 3;
GN   Name=GPR173; Synonyms=SREB3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004968; F:gonadotropin-releasing hormone receptor activity; IEA:Ensembl.
DR   GO; GO:2001223; P:negative regulation of neuron migration; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GP174_HUMAN             Reviewed;         333 AA.
AC   Q9BXC1; Q2M3F7;
DE   RecName: Full=Probable G-protein coupled receptor 174;
GN   Name=GPR174; ORFNames=FKSG79, GPCR17;
DR   GuidetoPHARMACOLOGY; 145; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GP176_HUMAN             Reviewed;         515 AA.
AC   Q14439; Q6NXF6;
DE   RecName: Full=Probable G-protein coupled receptor 176;
DE   AltName: Full=HB-954;
GN   Name=GPR176;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GP179_HUMAN             Reviewed;        2367 AA.
AC   Q6PRD1;
DE   RecName: Full=Probable G-protein coupled receptor 179;
DE   AltName: Full=Probable G-protein coupled receptor 158-like 1;
DE            Short=GPR158-like;
DE   Flags: Precursor;
GN   Name=GPR179; Synonyms=GPR158L, GPR158L1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   GP180_HUMAN             Reviewed;         440 AA.
AC   Q86V85; A8K1D5;
DE   RecName: Full=Integral membrane protein GPR180;
DE   AltName: Full=Intimal thickness-related receptor;
DE   Flags: Precursor;
GN   Name=GPR180; Synonyms=ITR;
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
//
ID   GP182_HUMAN             Reviewed;         404 AA.
AC   O15218;
DE   RecName: Full=G-protein coupled receptor 182;
GN   Name=GPR182; Synonyms=ADMR;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
//
ID   GP183_HUMAN             Reviewed;         361 AA.
AC   P32249; B2R8N5; Q53F99; Q5JUH7;
DE   RecName: Full=G-protein coupled receptor 183;
DE   AltName: Full=Epstein-Barr virus-induced G-protein coupled receptor 2;
DE            Short=EBI2;
DE            Short=EBV-induced G-protein coupled receptor 2;
GN   Name=GPR183; Synonyms=EBI2;
DR   GuidetoPHARMACOLOGY; 81; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008142; F:oxysterol binding; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002313; P:mature B cell differentiation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
//
ID   GP1BA_HUMAN             Reviewed;         652 AA.
AC   P07359; E7ES66; Q14441; Q16469; Q8N1F3; Q8NG39; Q9HDC7; Q9UEK1;
AC   Q9UQS4;
DE   RecName: Full=Platelet glycoprotein Ib alpha chain;
DE            Short=GP-Ib alpha;
DE            Short=GPIb-alpha;
DE            Short=GPIbA;
DE            Short=Glycoprotein Ibalpha;
DE   AltName: Full=Antigen CD42b-alpha;
DE   AltName: CD_antigen=CD42b;
DE   Contains:
DE     RecName: Full=Glycocalicin;
DE   Flags: Precursor;
GN   Name=GP1BA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015057; F:thrombin receptor activity; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IMP:MGI.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IDA:MGI.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042730; P:fibrinolysis; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:UniProtKB.
DR   GO; GO:0030193; P:regulation of blood coagulation; TAS:UniProtKB.
DR   GO; GO:0070493; P:thrombin receptor signaling pathway; TAS:GOC.
//
ID   GP1BB_HUMAN             Reviewed;         206 AA.
AC   P13224; Q14422; Q8NG40;
DE   RecName: Full=Platelet glycoprotein Ib beta chain;
DE            Short=GP-Ib beta;
DE            Short=GPIb-beta;
DE            Short=GPIbB;
DE   AltName: Full=Antigen CD42b-beta;
DE   AltName: CD_antigen=CD42c;
DE   Flags: Precursor;
GN   Name=GP1BB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
//
ID   GP2_HUMAN               Reviewed;         537 AA.
AC   P55259; A6NFM9; A6NJA8; Q13338; Q9UIF1;
DE   RecName: Full=Pancreatic secretory granule membrane major glycoprotein GP2;
DE   AltName: Full=Pancreatic zymogen granule membrane protein GP-2;
DE   AltName: Full=ZAP75;
DE   Flags: Precursor;
GN   Name=GP2;
DR   GO; GO:0003823; F:antigen binding; IEA:Ensembl.
DR   GO; GO:0002412; P:antigen transcytosis by M cells in mucosal-associated lymphoid tissue; IEA:Ensembl.
//
ID   GPA33_HUMAN             Reviewed;         319 AA.
AC   Q99795; Q5VZP6;
DE   RecName: Full=Cell surface A33 antigen;
DE   AltName: Full=Glycoprotein A33;
DE   Flags: Precursor;
GN   Name=GPA33;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
//
ID   GPAA1_HUMAN             Reviewed;         621 AA.
AC   O43292; Q9NSS0; Q9UQ31;
DE   RecName: Full=Glycosylphosphatidylinositol anchor attachment 1 protein;
DE            Short=GPI anchor attachment protein 1;
DE   AltName: Full=GAA1 protein homolog;
DE            Short=hGAA1;
GN   Name=GPAA1; Synonyms=GAA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; NAS:UniProtKB.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; NAS:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0006621; P:protein retention in ER lumen; NAS:UniProtKB.
//
ID   GPAM1_HUMAN             Reviewed;         340 AA.
AC   Q8IXQ4; A8K8X8; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q9C0F9; Q9H2R0;
AC   Q9P0W6;
DE   RecName: Full=GPALPP motifs-containing protein 1;
DE   AltName: Full=Lipopolysaccharide-specific response protein 7;
GN   Name=GPALPP1; Synonyms=KIAA1704, LSR7; ORFNames=AD029;
//
ID   GPAN1_HUMAN             Reviewed;         356 AA.
AC   O95872; A6NG25; B0UXA2; Q5SQ49;
DE   RecName: Full=G patch domain and ankyrin repeat-containing protein 1;
DE   AltName: Full=Ankyrin repeat domain-containing protein 59;
DE   AltName: Full=G patch domain-containing protein 10;
DE   AltName: Full=HLA-B-associated transcript 4;
DE   AltName: Full=Protein G5;
GN   Name=GPANK1; Synonyms=ANKRD59, BAT4, G5, GPATCH10;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   GPAT1_HUMAN             Reviewed;         828 AA.
AC   Q9HCL2; Q5VW51; Q86TA3;
DE   RecName: Full=Glycerol-3-phosphate acyltransferase 1, mitochondrial;
DE            Short=GPAT-1;
DE            EC=2.3.1.15;
DE   Flags: Precursor;
GN   Name=GPAM; Synonyms=GPAT1, KIAA1560;
DR   GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0055089; P:fatty acid homeostasis; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0070970; P:interleukin-2 secretion; IEA:Ensembl.
DR   GO; GO:0070236; P:negative regulation of activation-induced cell death of T cells; IEA:Ensembl.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0055091; P:phospholipid homeostasis; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0050707; P:regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IDA:UniProtKB.
//
ID   GPAT2_HUMAN             Reviewed;         795 AA.
AC   Q6NUI2; Q6P2E4; Q6ZNI3; Q6ZNI5; Q6ZWJ4;
DE   RecName: Full=Glycerol-3-phosphate acyltransferase 2, mitochondrial;
DE            Short=GPAT-2;
DE            EC=2.3.1.15;
DE   AltName: Full=xGPAT1;
GN   Name=GPAT2;
DR   GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; ISS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; ISS:UniProtKB.
//
ID   GPAT3_HUMAN             Reviewed;         434 AA.
AC   Q53EU6; Q68CJ4; Q6GPI6; Q96NA3;
DE   RecName: Full=Glycerol-3-phosphate acyltransferase 3;
DE            Short=GPAT-3;
DE            EC=2.3.1.15;
DE   AltName: Full=1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10;
DE            Short=AGPAT 10;
DE   AltName: Full=1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9;
DE            Short=1-AGP acyltransferase 9;
DE            Short=1-AGPAT 9;
DE            EC=2.3.1.51;
DE   AltName: Full=Acyl-CoA:glycerol-3-phosphate acyltransferase 3;
DE            Short=hGPAT3;
DE   AltName: Full=Lung cancer metastasis-associated protein 1;
DE   AltName: Full=Lysophosphatidic acid acyltransferase theta;
DE            Short=LPAAT-theta;
DE   AltName: Full=MAG-1;
GN   Name=AGPAT9; Synonyms=GPAT3, MAG1; ORFNames=HMFN0839, UNQ2753/PRO6492;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0032006; P:regulation of TOR signaling; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IDA:UniProtKB.
//
ID   GPAT4_HUMAN             Reviewed;         456 AA.
AC   Q86UL3; Q86V89;
DE   RecName: Full=Glycerol-3-phosphate acyltransferase 4;
DE            Short=GPAT4;
DE            EC=2.3.1.15;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 6;
DE            Short=1-AGP acyltransferase 6;
DE            Short=1-AGPAT 6;
DE   AltName: Full=Acyl-CoA:glycerol-3-phosphate acyltransferase 4;
DE   AltName: Full=Lysophosphatidic acid acyltransferase zeta;
DE            Short=LPAAT-zeta;
DE   Flags: Precursor;
GN   Name=AGPAT6; Synonyms=GPAT4; ORFNames=UNQ551/PRO1108;
DR   GO; GO:0004366; F:glycerol-3-phosphate O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046339; P:diacylglycerol metabolic process; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0002071; P:glandular epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; ISS:UniProtKB.
DR   GO; GO:0008610; P:lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; ISS:UniProtKB.
//
ID   GPBAR_HUMAN             Reviewed;         330 AA.
AC   Q8TDU6; B3KV35;
DE   RecName: Full=G-protein coupled bile acid receptor 1;
DE   AltName: Full=G-protein coupled receptor GPCR19;
DE            Short=hGPCR19;
DE   AltName: Full=Membrane-type receptor for bile acids;
DE            Short=M-BAR;
DE   AltName: Full=hBG37;
DE            Short=BG37;
GN   Name=GPBAR1; Synonyms=TGR5;
DR   GuidetoPHARMACOLOGY; 37; -.
DR   GO; GO:0038181; F:bile acid receptor activity; IDA:UniProtKB.
DR   GO; GO:0038182; F:G-protein coupled bile acid receptor activity; NAS:UniProtKB.
DR   GO; GO:0038184; P:cell surface bile acid receptor signaling pathway; IC:UniProtKB.
//
ID   GPBP1_HUMAN             Reviewed;         473 AA.
AC   Q86WP2; A6NKW3; Q6NSH6; Q9H0D4; Q9H785; Q9NSN4;
DE   RecName: Full=Vasculin;
DE   AltName: Full=GC-rich promoter-binding protein 1;
DE   AltName: Full=Vascular wall-linked protein;
GN   Name=GPBP1; Synonyms=GPBP, SSH6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GPBL1_HUMAN             Reviewed;         474 AA.
AC   Q9HC44; D3DQ10; Q9H751;
DE   RecName: Full=Vasculin-like protein 1;
DE   AltName: Full=GC-rich promoter-binding protein 1-like 1;
GN   Name=GPBP1L1; ORFNames=SP192;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GPC1_HUMAN              Reviewed;         558 AA.
AC   P35052; Q53QM4;
DE   RecName: Full=Glypican-1;
DE   Contains:
DE     RecName: Full=Secreted glypican-1;
DE   Flags: Precursor;
GN   Name=GPC1;
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0017134; F:fibroblast growth factor binding; ISS:UniProtKB.
DR   GO; GO:0043236; F:laminin binding; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030200; P:heparan sulfate proteoglycan catabolic process; IDA:UniProtKB.
DR   GO; GO:0032288; P:myelin assembly; ISS:UniProtKB.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:2001016; P:positive regulation of skeletal muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0014037; P:Schwann cell differentiation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPC2_HUMAN              Reviewed;         579 AA.
AC   Q8N158; A4D2A7;
DE   RecName: Full=Glypican-2;
DE   Contains:
DE     RecName: Full=Secreted glypican-2;
DE   Flags: Precursor;
GN   Name=GPC2;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   GPC3_HUMAN              Reviewed;         580 AA.
AC   P51654; C9JLE3; G3V1R0; Q2L880; Q2L882;
DE   RecName: Full=Glypican-3;
DE   AltName: Full=GTR2-2;
DE   AltName: Full=Intestinal protein OCI-5;
DE   AltName: Full=MXR7;
DE   Contains:
DE     RecName: Full=Secreted glypican-3;
DE   Flags: Precursor;
GN   Name=GPC3; Synonyms=OCI5;
DR   GO; GO:0060422; F:peptidyl-dipeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0010171; P:body morphogenesis; IEA:Ensembl.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0072203; P:cell proliferation involved in metanephros development; IEA:Ensembl.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0060976; P:coronary vasculature development; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0072138; P:mesenchymal cell proliferation involved in ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0072180; P:mesonephric duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045926; P:negative regulation of growth; IEA:Ensembl.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:2000096; P:positive regulation of Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPC4_HUMAN              Reviewed;         556 AA.
AC   O75487; B2R6J7; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9;
DE   RecName: Full=Glypican-4;
DE   AltName: Full=K-glypican;
DE   Contains:
DE     RecName: Full=Secreted glypican-4;
DE   Flags: Precursor;
GN   Name=GPC4; ORFNames=UNQ474/PRO937;
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPC5B_HUMAN             Reviewed;         403 AA.
AC   Q9NZH0; D2DFB0; O75205; Q8NBZ8;
DE   RecName: Full=G-protein coupled receptor family C group 5 member B;
DE   AltName: Full=A-69G12.1;
DE   AltName: Full=Retinoic acid-induced gene 2 protein;
DE            Short=RAIG-2;
DE   Flags: Precursor;
GN   Name=GPRC5B; Synonyms=RAIG2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; ISS:UniProt.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:MGI.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProt.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:UniProt.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProt.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProt.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; ISS:UniProt.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProt.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; ISS:UniProt.
//
ID   GPC5C_HUMAN             Reviewed;         441 AA.
AC   Q9NQ84; B5BUN4; Q2NL85; Q9NZG5;
DE   RecName: Full=G-protein coupled receptor family C group 5 member C;
DE   AltName: Full=Retinoic acid-induced gene 3 protein;
DE            Short=RAIG-3;
DE   Flags: Precursor;
GN   Name=GPRC5C; Synonyms=RAIG3; ORFNames=PSEC0087;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPC5D_HUMAN             Reviewed;         345 AA.
AC   Q9NZD1; Q3KNV3; Q7Z5J9; Q8TDS6;
DE   RecName: Full=G-protein coupled receptor family C group 5 member D;
GN   Name=GPRC5D;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPC5_HUMAN              Reviewed;         572 AA.
AC   P78333; B2R726; O60436; Q9BX27;
DE   RecName: Full=Glypican-5;
DE   Contains:
DE     RecName: Full=Secreted glypican-5;
DE   Flags: Precursor;
GN   Name=GPC5;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPC6A_HUMAN             Reviewed;         926 AA.
AC   Q5T6X5; Q6JK43; Q6JK44; Q8NGU8; Q8NHZ9; Q8TDT6;
DE   RecName: Full=G-protein coupled receptor family C group 6 member A;
DE            Short=hGPRC6A;
DE   AltName: Full=G-protein coupled receptor GPCR33;
DE            Short=hGPCR33;
DE   Flags: Precursor;
GN   Name=GPRC6A;
DR   GuidetoPHARMACOLOGY; 55; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IDA:UniProtKB.
//
ID   GPC6_HUMAN              Reviewed;         555 AA.
AC   Q9Y625; A8K279; Q96SG5; Q96SG8; Q9H1P4;
DE   RecName: Full=Glypican-6;
DE   Contains:
DE     RecName: Full=Secreted glypican-6;
DE   Flags: Precursor;
GN   Name=GPC6; ORFNames=UNQ369/PRO705;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPCP1_HUMAN             Reviewed;         672 AA.
AC   Q9NPB8; D3DW06; Q9BQL8; Q9NUX0;
DE   RecName: Full=Glycerophosphocholine phosphodiesterase GPCPD1;
DE            EC=3.1.4.2;
DE   AltName: Full=Glycerophosphodiester phosphodiesterase 5;
GN   Name=GPCPD1; Synonyms=GDE5, KIAA1434;
DR   GO; GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:2001070; F:starch binding; IEA:InterPro.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:InterPro.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPD1L_HUMAN             Reviewed;         351 AA.
AC   Q8N335; A8K9U3; Q14702; Q9BRM5;
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase 1-like protein;
DE            Short=GPD1-L;
DE            EC=1.1.1.8;
GN   Name=GPD1L; Synonyms=KIAA0089;
DR   GO; GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0017080; F:sodium channel regulator activity; IMP:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0019674; P:NAD metabolic process; IMP:BHF-UCL.
DR   GO; GO:0006734; P:NADH metabolic process; IEA:Ensembl.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0090038; P:negative regulation of protein kinase C signaling; IMP:BHF-UCL.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:2000010; P:positive regulation of protein localization to cell surface; IMP:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IMP:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IMP:BHF-UCL.
DR   GO; GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   GPDA_HUMAN              Reviewed;         349 AA.
AC   P21695; F8W1L5; Q8N1B0;
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic;
DE            Short=GPD-C;
DE            Short=GPDH-C;
DE            EC=1.1.1.8;
GN   Name=GPD1;
DR   GO; GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+] activity; TAS:ProtInc.
DR   GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IEA:InterPro.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006116; P:NADH oxidation; IEA:Ensembl.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   GPDM_HUMAN              Reviewed;         727 AA.
AC   P43304; A8K4V0; B3KSA9; Q59FR1; Q9HAP9;
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase, mitochondrial;
DE            Short=GPD-M;
DE            Short=GPDH-M;
DE            EC=1.1.5.3;
DE   AltName: Full=mtGPD;
DE   Flags: Precursor;
GN   Name=GPD2;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0052591; F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GPER1_HUMAN             Reviewed;         375 AA.
AC   Q99527; A8K6C5; B5BUJ1; O00143; O43494; Q13631; Q6FHL1; Q96F42;
AC   Q99981;
DE   RecName: Full=G-protein coupled estrogen receptor 1;
DE   AltName: Full=Chemoattractant receptor-like 2;
DE   AltName: Full=Flow-induced endothelial G-protein coupled receptor 1;
DE            Short=FEG-1;
DE   AltName: Full=G protein-coupled estrogen receptor 1;
DE   AltName: Full=G-protein coupled receptor 30;
DE   AltName: Full=GPCR-Br;
DE   AltName: Full=IL8-related receptor DRY12;
DE   AltName: Full=Lymphocyte-derived G-protein coupled receptor;
DE            Short=LYGPR;
DE   AltName: Full=Membrane estrogen receptor;
DE            Short=mER;
GN   Name=GPER1; Synonyms=CEPR, CMKRL2, DRY12, GPER, GPR30;
DR   GuidetoPHARMACOLOGY; 221; -.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0030284; F:estrogen receptor activity; IDA:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0017082; F:mineralocorticoid receptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005496; F:steroid binding; IDA:UniProtKB.
DR   GO; GO:0030263; P:apoptotic chromosome condensation; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IDA:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0071389; P:cellular response to mineralocorticoid stimulus; ISS:UniProtKB.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0031959; P:mineralocorticoid receptor signaling pathway; ISS:GOC.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051053; P:negative regulation of DNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:0002695; P:negative regulation of leukocyte activation; IDA:UniProtKB.
DR   GO; GO:0051055; P:negative regulation of lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0019228; P:neuronal action potential; ISS:UniProtKB.
DR   GO; GO:0030264; P:nuclear fragmentation involved in apoptotic nuclear change; ISS:UniProtKB.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:UniProtKB.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0001956; P:positive regulation of neurotransmitter secretion; ISS:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; ISS:UniProtKB.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IDA:GOC.
//
ID   GPHA2_HUMAN             Reviewed;         129 AA.
AC   Q96T91; Q52LE2;
DE   RecName: Full=Glycoprotein hormone alpha-2;
DE   AltName: Full=Putative secreted protein Zsig51;
DE   AltName: Full=Thyrostimulin subunit alpha;
DE   Flags: Precursor;
GN   Name=GPHA2; Synonyms=GPA2, ZSIG51;
//
ID   GPHB5_HUMAN             Reviewed;         130 AA.
AC   Q86YW7; Q6NTD0; Q8NFW2;
DE   RecName: Full=Glycoprotein hormone beta-5;
DE   AltName: Full=Thyrostimulin subunit beta;
DE   Flags: Precursor;
GN   Name=GPHB5; Synonyms=GPB5, ZLUT1;
//
ID   GPHRA_HUMAN             Reviewed;         455 AA.
AC   B7ZAQ6; A6NN37; B2RUV3; B3KMN3; B4DXE7; Q53FQ9; Q5T2V8; Q5T5P5;
AC   Q659E2; Q6NVY5; Q9P0S4; Q9Y302;
DE   RecName: Full=Golgi pH regulator A;
DE   AltName: Full=Protein GPR89A;
DE   AltName: Full=Putative MAPK-activating protein PM01;
DE   AltName: Full=Putative NF-kappa-B-activating protein 90;
GN   Name=GPR89A; Synonyms=GPHRA, GPR89, SH120;
GN   ORFNames=CGI-13, UNQ192/PRO218;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008308; F:voltage-gated anion channel activity; IDA:UniProtKB.
DR   GO; GO:0051452; P:intracellular pH reduction; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0044070; P:regulation of anion transport; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   GPHRB_HUMAN             Reviewed;         455 AA.
AC   P0CG08; A6NN37; B2RUV3; B3KMN3; Q53FQ9; Q5T2V8; Q5T5P5; Q659E2;
AC   Q6NVY5; Q9P0S4; Q9Y302;
DE   RecName: Full=Golgi pH regulator B;
DE   AltName: Full=Protein GPR89B;
GN   Name=GPR89B; Synonyms=GPHRB; ORFNames=HSPC201;
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   GPHRC_HUMAN             Reviewed;         320 AA.
AC   A6NKF9;
DE   RecName: Full=Putative Golgi pH regulator C;
DE   AltName: Full=Protein GPR89C;
GN   Name=GPR89C; Synonyms=GPHRC;
//
ID   GPI8_HUMAN              Reviewed;         395 AA.
AC   Q92643; B2R7K3; O14822; Q5TG77;
DE   RecName: Full=GPI-anchor transamidase;
DE            Short=GPI transamidase;
DE            EC=3.-.-.-;
DE   AltName: Full=GPI8 homolog;
DE            Short=hGPI8;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein;
DE            Short=PIG-K;
DE   Flags: Precursor;
GN   Name=PIGK; Synonyms=GPI8;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0003923; F:GPI-anchor transamidase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; TAS:UniProtKB.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; TAS:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:GOC.
//
ID   GPIX_HUMAN              Reviewed;         177 AA.
AC   P14770; Q14445; Q8N1D1; Q92525;
DE   RecName: Full=Platelet glycoprotein IX;
DE            Short=GP-IX;
DE            Short=GPIX;
DE   AltName: Full=Glycoprotein 9;
DE   AltName: CD_antigen=CD42a;
DE   Flags: Precursor;
GN   Name=GP9;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
//
ID   GPKOW_HUMAN             Reviewed;         476 AA.
AC   Q92917; Q59EK5; Q9BQA8;
DE   RecName: Full=G patch domain and KOW motifs-containing protein;
DE   AltName: Full=G patch domain-containing protein 5;
DE   AltName: Full=Protein MOS2 homolog;
DE   AltName: Full=Protein T54;
GN   Name=GPKOW; Synonyms=GPATC5, GPATCH5, T54;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GPM6A_HUMAN             Reviewed;         278 AA.
AC   P51674; B7Z642; E9PHI5; Q92602;
DE   RecName: Full=Neuronal membrane glycoprotein M6-a;
DE            Short=M6a;
GN   Name=GPM6A; Synonyms=M6A;
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0003407; P:neural retina development; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IDA:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; IDA:UniProtKB.
DR   GO; GO:0007416; P:synapse assembly; ISS:UniProtKB.
//
ID   GPM6B_HUMAN             Reviewed;         265 AA.
AC   Q13491; O76077; Q86X43; Q8N956;
DE   RecName: Full=Neuronal membrane glycoprotein M6-b;
DE            Short=M6b;
GN   Name=GPM6B; Synonyms=M6B;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0085029; P:extracellular matrix assembly; IMP:UniProtKB.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; ISS:UniProtKB.
DR   GO; GO:0051612; P:negative regulation of serotonin uptake; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; IMP:UniProtKB.
//
ID   GPN2_HUMAN              Reviewed;         310 AA.
AC   Q9H9Y4; Q96HG4; Q9NUE1; Q9NW30;
DE   RecName: Full=GPN-loop GTPase 2;
DE   AltName: Full=ATP-binding domain 1 family member B;
GN   Name=GPN2; Synonyms=ATPBD1B; ORFNames=UNQ5828/PRO19647;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GPN1_HUMAN              Reviewed;         374 AA.
AC   Q9HCN4; B4DQJ5; B4DQM4; B4DXU4; B5MBZ5; O76004;
DE   RecName: Full=GPN-loop GTPase 1;
DE   AltName: Full=MBD2-interacting protein;
DE            Short=MBDin;
DE   AltName: Full=XPA-binding protein 1;
GN   Name=GPN1; Synonyms=MBDIN, XAB1; ORFNames=HUSSY-23;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   GPN3_HUMAN              Reviewed;         284 AA.
AC   Q9UHW5; B2RC54; D4YWV1; F5H759; Q53FS3; Q6UVZ6; Q7Z3D3; Q8NEI2;
AC   Q96HK9;
DE   RecName: Full=GPN-loop GTPase 3;
DE   AltName: Full=ATP-binding domain 1 family member C;
GN   Name=GPN3; Synonyms=ATPBD1C; ORFNames=AD-009, UNQ1876/PRO4319;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GPNMB_HUMAN             Reviewed;         572 AA.
AC   Q14956; A4D155; Q6UVX1; Q8N1A1;
DE   RecName: Full=Transmembrane glycoprotein NMB;
DE   AltName: Full=Transmembrane glycoprotein HGFIN;
DE   Flags: Precursor;
GN   Name=GPNMB; Synonyms=HGFIN, NMB; ORFNames=UNQ1725/PRO9925;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
//
ID   GPR12_HUMAN             Reviewed;         334 AA.
AC   P47775; Q5T8P3;
DE   RecName: Full=G-protein coupled receptor 12;
GN   Name=GPR12;
DR   GuidetoPHARMACOLOGY; 86; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR15_HUMAN             Reviewed;         360 AA.
AC   P49685; Q3MIL4; Q6ISN6;
DE   RecName: Full=G-protein coupled receptor 15;
DE   AltName: Full=Brother of Bonzo;
DE            Short=BoB;
GN   Name=GPR15;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR17_HUMAN             Reviewed;         367 AA.
AC   Q13304; A8K9L0; B2R9X0; Q8N5S7; Q9UDZ6; Q9UE21;
DE   RecName: Full=Uracil nucleotide/cysteinyl leukotriene receptor;
DE            Short=UDP/CysLT receptor;
DE   AltName: Full=G-protein coupled receptor 17;
DE   AltName: Full=P2Y-like receptor;
DE   AltName: Full=R12;
GN   Name=GPR17;
DR   GuidetoPHARMACOLOGY; 88; -.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR18_HUMAN             Reviewed;         331 AA.
AC   Q14330; Q6GTM3; Q96HI6; Q9H2L2;
DE   RecName: Full=N-arachidonyl glycine receptor;
DE            Short=NAGly receptor;
DE   AltName: Full=G-protein coupled receptor 18;
GN   Name=GPR18; Synonyms=GPCRW;
DR   GuidetoPHARMACOLOGY; 89; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
//
ID   GPR19_HUMAN             Reviewed;         415 AA.
AC   Q15760;
DE   RecName: Full=Probable G-protein coupled receptor 19;
DE   AltName: Full=GPR-NGA;
GN   Name=GPR19;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR1_HUMAN              Reviewed;         355 AA.
AC   P46091; A5JUU6; A8K4L1; Q53TR9; Q6NVX4;
DE   RecName: Full=G-protein coupled receptor 1;
GN   Name=GPR1;
DR   GuidetoPHARMACOLOGY; 82; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR20_HUMAN             Reviewed;         358 AA.
AC   Q99678; Q17R96;
DE   RecName: Full=G-protein coupled receptor 20;
GN   Name=GPR20;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
//
ID   GPR21_HUMAN             Reviewed;         349 AA.
AC   Q99679; B2R8W9; Q6NXU2;
DE   RecName: Full=Probable G-protein coupled receptor 21;
GN   Name=GPR21;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
//
ID   GPR22_HUMAN             Reviewed;         433 AA.
AC   Q99680; O14554;
DE   RecName: Full=Probable G-protein coupled receptor 22;
GN   Name=GPR22;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR25_HUMAN             Reviewed;         361 AA.
AC   O00155; A0AVJ5;
DE   RecName: Full=Probable G-protein coupled receptor 25;
GN   Name=GPR25;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR26_HUMAN             Reviewed;         337 AA.
AC   Q8NDV2; Q2M2E2;
DE   RecName: Full=G-protein coupled receptor 26;
GN   Name=GPR26;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
//
ID   GPR27_HUMAN             Reviewed;         375 AA.
AC   Q9NS67;
DE   RecName: Full=Probable G-protein coupled receptor 27;
DE   AltName: Full=Super conserved receptor expressed in brain 1;
GN   Name=GPR27; Synonyms=SREB1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GPR31_HUMAN             Reviewed;         319 AA.
AC   O00270; B0M0K2; Q4VBL3; Q9NQ20;
DE   RecName: Full=12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor;
DE            Short=12-(S)-HETE receptor;
DE            Short=12-HETER;
DE   AltName: Full=G-protein coupled receptor 31;
GN   Name=GPR31;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR32_HUMAN             Reviewed;         356 AA.
AC   O75388; Q502U7; Q6NWS5;
DE   RecName: Full=Probable G-protein coupled receptor 32;
GN   Name=GPR32;
DR   GuidetoPHARMACOLOGY; 99; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR33_HUMAN             Reviewed;         333 AA.
AC   Q49SQ1;
DE   RecName: Full=Probable G-protein coupled receptor 33;
GN   Name=GPR33;
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
//
ID   GPR35_HUMAN             Reviewed;         309 AA.
AC   Q9HC97; J3KR30; O43495; Q17R58; Q4VBN5; Q4ZFV2; Q6FHI8; Q86UH4;
DE   RecName: Full=G-protein coupled receptor 35;
DE   AltName: Full=Kynurenic acid receptor;
DE            Short=KYNA receptor;
GN   Name=GPR35;
DR   GuidetoPHARMACOLOGY; 102; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
//
ID   GPR34_HUMAN             Reviewed;         381 AA.
AC   Q9UPC5; O95853;
DE   RecName: Full=Probable G-protein coupled receptor 34;
GN   Name=GPR34;
DR   GuidetoPHARMACOLOGY; 101; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR37_HUMAN             Reviewed;         613 AA.
AC   O15354; A4D0Y6; O00348; O14768; Q8TD39;
DE   RecName: Full=Prosaposin receptor GPR37;
DE   AltName: Full=Endothelin B receptor-like protein 1;
DE            Short=ETBR-LP-1;
DE   AltName: Full=G-protein coupled receptor 37;
DE   AltName: Full=Parkin-associated endothelin receptor-like receptor;
DE            Short=PAELR;
DE   Flags: Precursor;
GN   Name=GPR37;
DR   GuidetoPHARMACOLOGY; 103; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR39_HUMAN             Reviewed;         453 AA.
AC   O43194; B2RC12; B6V9G4; Q08AS2; Q53R01;
DE   RecName: Full=G-protein coupled receptor 39;
GN   Name=GPR39;
DR   GuidetoPHARMACOLOGY; 105; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR3_HUMAN              Reviewed;         330 AA.
AC   P46089; A8K570;
DE   RecName: Full=G-protein coupled receptor 3;
DE   AltName: Full=ACCA orphan receptor;
GN   Name=GPR3; Synonyms=ACCA;
DR   GuidetoPHARMACOLOGY; 83; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0040020; P:regulation of meiosis; IEA:Ensembl.
//
ID   GPR42_HUMAN             Reviewed;         346 AA.
AC   O15529;
DE   RecName: Full=G-protein coupled receptor 42;
GN   Name=GPR42; Synonyms=GPR42P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR45_HUMAN             Reviewed;         372 AA.
AC   Q9Y5Y3; Q6NWS4; Q6NXU6;
DE   RecName: Full=Probable G-protein coupled receptor 45;
DE   AltName: Full=PSP24-1;
DE   AltName: Full=PSP24-alpha;
GN   Name=GPR45;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPR4_HUMAN              Reviewed;         362 AA.
AC   P46093; A8K3T3; B0M0K1; Q6NWM4;
DE   RecName: Full=G-protein coupled receptor 4;
DE   AltName: Full=G-protein coupled receptor 19;
GN   Name=GPR4; Synonyms=GPR19;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR52_HUMAN             Reviewed;         361 AA.
AC   Q9Y2T5; O75654; Q4VBL6; Q6ISM0;
DE   RecName: Full=Probable G-protein coupled receptor 52;
GN   Name=GPR52;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR55_HUMAN             Reviewed;         319 AA.
AC   Q9Y2T6; Q8N580;
DE   RecName: Full=G-protein coupled receptor 55;
GN   Name=GPR55;
DR   GuidetoPHARMACOLOGY; 109; -.
DR   GO; GO:0004949; F:cannabinoid receptor activity; IDA:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0045453; P:bone resorption; IDA:UniProtKB.
DR   GO; GO:0038171; P:cannabinoid signaling pathway; IDA:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IDA:UniProtKB.
//
ID   GPR56_HUMAN             Reviewed;         693 AA.
AC   Q9Y653; A6NIT7; A6NJV9; B0M0K4; B4DR54; O95966; Q6ZMP1; Q8NGB3;
AC   Q96HB4;
DE   RecName: Full=G-protein coupled receptor 56;
DE   AltName: Full=Protein TM7XN1;
DE   Contains:
DE     RecName: Full=GPR56 N-terminal fragment;
DE              Short=GPR56 NT;
DE              Short=GPR56(N);
DE     AltName: Full=GPR56 extracellular subunit;
DE     AltName: Full=GPR56 subunit alpha;
DE   Contains:
DE     RecName: Full=GPR56 C-terminal fragment;
DE              Short=GPR56 CT;
DE              Short=GPR56(C);
DE     AltName: Full=GPR56 seven-transmembrane subunit;
DE              Short=GPR56 7TM;
DE     AltName: Full=GPR56 subunit beta;
DE   Flags: Precursor;
GN   Name=GPR56; Synonyms=TM7LN4, TM7XN1; ORFNames=UNQ540/PRO1083;
DR   GO; GO:0005518; F:collagen binding; ISS:UniProtKB.
DR   GO; GO:0050840; F:extracellular matrix binding; ISS:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:GDB.
DR   GO; GO:0007155; P:cell adhesion; IDA:GDB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0021801; P:cerebral cortex radial glia guided migration; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2001223; P:negative regulation of neuron migration; ISS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0070528; P:protein kinase C signaling; IDA:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0010573; P:vascular endothelial growth factor production; IDA:UniProtKB.
//
ID   GPR62_HUMAN             Reviewed;         368 AA.
AC   Q9BZJ7; F1DAM4; Q5KU27;
DE   RecName: Full=Probable G-protein coupled receptor 62;
DE   AltName: Full=G-protein coupled receptor GPCR8;
DE            Short=hGPCR8;
DE   AltName: Full=G-protein coupled receptor KPG_005;
GN   Name=GPR62;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPR63_HUMAN             Reviewed;         419 AA.
AC   Q9BZJ6; Q9UJH3;
DE   RecName: Full=Probable G-protein coupled receptor 63;
DE   AltName: Full=PSP24-2;
DE   AltName: Full=PSP24-beta;
GN   Name=GPR63; Synonyms=PSP24B;
DR   GuidetoPHARMACOLOGY; 112; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPR64_HUMAN             Reviewed;        1017 AA.
AC   Q8IZP9; B1AWB3; B1AWB4; B1AWB6; B1AWB7; O00406; Q14CE0; Q8IWT2;
AC   Q8IZE4; Q8IZE5; Q8IZE6; Q8IZE7; Q8IZP3; Q8IZP4;
DE   RecName: Full=G-protein coupled receptor 64;
DE   AltName: Full=Human epididymis-specific protein 6;
DE            Short=He6;
DE   Flags: Precursor;
GN   Name=GPR64; Synonyms=HE6, TM7LN2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   GPR61_HUMAN             Reviewed;         451 AA.
AC   Q9BZJ8; A8K1W2; Q6NWS0; Q8TDV4; Q96PR4;
DE   RecName: Full=Probable G-protein coupled receptor 61;
DE   AltName: Full=Biogenic amine receptor-like G-protein coupled receptor;
GN   Name=GPR61; Synonyms=BALGR;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPR6_HUMAN              Reviewed;         362 AA.
AC   P46095; Q17RJ7; Q5SYL0;
DE   RecName: Full=G-protein coupled receptor 6;
DE   AltName: Full=Sphingosine 1-phosphate receptor GPR6;
GN   Name=GPR6;
DR   GuidetoPHARMACOLOGY; 85; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
//
ID   GPR75_HUMAN             Reviewed;         540 AA.
AC   O95800; B2RC02; Q6NWR2;
DE   RecName: Full=Probable G-protein coupled receptor 75;
GN   Name=GPR75;
DR   GuidetoPHARMACOLOGY; 115; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   GPR78_HUMAN             Reviewed;         363 AA.
AC   Q96P69; Q8NGV3;
DE   RecName: Full=G-protein coupled receptor 78;
GN   Name=GPR78; ORFNames=UNQ5925/PRO19818;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
//
ID   GPR82_HUMAN             Reviewed;         336 AA.
AC   Q96P67; Q5VT13;
DE   RecName: Full=Probable G-protein coupled receptor 82;
GN   Name=GPR82;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPR83_HUMAN             Reviewed;         423 AA.
AC   Q9NYM4; B0M0K5; Q6NWR4; Q9P1Y8;
DE   RecName: Full=Probable G-protein coupled receptor 83;
DE   AltName: Full=G-protein coupled receptor 72;
DE   Flags: Precursor;
GN   Name=GPR83; Synonyms=GPR72, KIAA1540;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
//
ID   GPR84_HUMAN             Reviewed;         396 AA.
AC   Q9NQS5; B6V9G7;
DE   RecName: Full=G-protein coupled receptor 84;
DE   AltName: Full=Inflammation-related G-protein coupled receptor EX33;
GN   Name=GPR84; Synonyms=EX33;
DR   GuidetoPHARMACOLOGY; 120; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   GPR85_HUMAN             Reviewed;         370 AA.
AC   P60893; Q9JHI6; Q9NPD1;
DE   RecName: Full=Probable G-protein coupled receptor 85;
DE   AltName: Full=Super conserved receptor expressed in brain 2;
GN   Name=GPR85; Synonyms=SREB2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   GPR88_HUMAN             Reviewed;         384 AA.
AC   Q9GZN0; Q29S24; Q6VN48;
DE   RecName: Full=Probable G-protein coupled receptor 88;
DE   AltName: Full=Striatum-specific G-protein coupled receptor;
GN   Name=GPR88; Synonyms=STRG;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
//
ID   GPR87_HUMAN             Reviewed;         358 AA.
AC   Q9BY21; Q5KU35; Q96JZ8; Q9BXC2;
DE   RecName: Full=G-protein coupled receptor 87;
DE   AltName: Full=G-protein coupled receptor 95;
GN   Name=GPR87; Synonyms=GPR95; ORFNames=FKSG78;
DR   GuidetoPHARMACOLOGY; 122; -.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IEA:InterPro.
//
ID   GPR97_HUMAN             Reviewed;         549 AA.
AC   Q86Y34; Q6ZMF4; Q86SL9; Q8IZF1;
DE   RecName: Full=Probable G-protein coupled receptor 97;
DE   AltName: Full=G-protein coupled receptor PGR26;
DE   Flags: Precursor;
GN   Name=GPR97; Synonyms=PGR26;
DR   GuidetoPHARMACOLOGY; 188; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   GPR98_HUMAN             Reviewed;        6306 AA.
AC   Q8WXG9; O75171; Q8TF58; Q9H0X5; Q9UL61;
DE   RecName: Full=G-protein coupled receptor 98;
DE   AltName: Full=Monogenic audiogenic seizure susceptibility protein 1 homolog;
DE   AltName: Full=Usher syndrome type-2C protein;
DE   AltName: Full=Very large G-protein coupled receptor 1;
DE   Flags: Precursor;
GN   Name=GPR98; Synonyms=KIAA0686, KIAA1943, MASS1, VLGR1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:HGNC.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0060122; P:inner ear receptor stereocilium organization; IEA:Ensembl.
DR   GO; GO:0048496; P:maintenance of organ identity; IMP:HGNC.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0050877; P:neurological system process; IMP:HGNC.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   GPRL1_HUMAN             Reviewed;         242 AA.
AC   Q6UWM5; Q96L06;
DE   RecName: Full=GLIPR1-like protein 1;
DE   Flags: Precursor;
GN   Name=GLIPR1L1; ORFNames=UNQ2972/PRO7434;
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
//
ID   GPS2_HUMAN              Reviewed;         327 AA.
AC   Q13227; Q6FHM8;
DE   RecName: Full=G protein pathway suppressor 2;
DE            Short=GPS-2;
GN   Name=GPS2;
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   GPSM1_HUMAN             Reviewed;         675 AA.
AC   Q86YR5; A9Z1X4; B1B0W3; Q86SR5; Q969T1; Q9UFS8;
DE   RecName: Full=G-protein-signaling modulator 1;
DE   AltName: Full=Activator of G-protein signaling 3;
GN   Name=GPSM1; Synonyms=AGS3;
DR   GO; GO:0005092; F:GDP-dissociation inhibitor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:InterPro.
//
ID   GPSM2_HUMAN             Reviewed;         684 AA.
AC   P81274; Q5T1N8; Q6IBL7; Q8N0Z5;
DE   RecName: Full=G-protein-signaling modulator 2;
DE   AltName: Full=Mosaic protein LGN;
GN   Name=GPSM2; Synonyms=LGN;
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
//
ID   GPSM3_HUMAN             Reviewed;         160 AA.
AC   Q9Y4H4; A2BFJ3;
DE   RecName: Full=G-protein-signaling modulator 3;
DE   AltName: Full=Activator of G-protein signaling 4;
DE   AltName: Full=G18.1b;
DE   AltName: Full=Protein G18;
GN   Name=GPSM3; Synonyms=AGS4, C6orf9, G18;
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
//
ID   GPT11_HUMAN             Reviewed;         259 AA.
AC   Q8N954; A8K0D9; B7Z2G4; B8ZZ44;
DE   RecName: Full=G patch domain-containing protein 11;
DE   AltName: Full=Coiled-coil domain-containing protein 75;
GN   Name=GPATCH11; Synonyms=CCDC75;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   GPT2L_HUMAN             Reviewed;         482 AA.
AC   Q9NWQ4; B3KN42; Q6PEJ7; Q9H3M3; Q9NWH0; Q9ULR8;
DE   RecName: Full=G patch domain-containing protein 2-like;
GN   Name=GPATCH2L; Synonyms=C14orf118, KIAA1152;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GPTC1_HUMAN             Reviewed;         931 AA.
AC   Q9BRR8; Q8IZV6; Q8N3B7; Q9NW94;
DE   RecName: Full=G patch domain-containing protein 1;
DE   AltName: Full=Evolutionarily conserved G-patch domain-containing protein;
GN   Name=GPATCH1; Synonyms=ECGP, GPATC1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   GPTC2_HUMAN             Reviewed;         528 AA.
AC   Q9NW75; Q5VYK7; Q5VYK8; Q86YE7;
DE   RecName: Full=G patch domain-containing protein 2;
GN   Name=GPATCH2; Synonyms=GPATC2;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   GPTC3_HUMAN             Reviewed;         525 AA.
AC   Q96I76; Q5JYH2; Q8NDJ2; Q9H9Z3;
DE   RecName: Full=G patch domain-containing protein 3;
GN   Name=GPATCH3; Synonyms=GPATC3;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   GPTC4_HUMAN             Reviewed;         446 AA.
AC   Q5T3I0; Q5T3I1; Q6ZUE7; Q8IWG8; Q9NXH4;
DE   RecName: Full=G patch domain-containing protein 4;
GN   Name=GPATCH4; Synonyms=GPATC4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   GPTC8_HUMAN             Reviewed;        1502 AA.
AC   Q9UKJ3; B9EGP9; O60300; Q8TB99;
DE   RecName: Full=G patch domain-containing protein 8;
GN   Name=GPATCH8; Synonyms=GPATC8, KIAA0553;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GPT_HUMAN               Reviewed;         408 AA.
AC   Q9H3H5; O15216; Q86WV9; Q9BWE6;
DE   RecName: Full=UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase;
DE            EC=2.7.8.15;
DE   AltName: Full=GlcNAc-1-P transferase;
DE            Short=G1PT;
DE            Short=GPT;
DE   AltName: Full=N-acetylglucosamine-1-phosphate transferase;
GN   Name=DPAGT1; Synonyms=DPAGT2;
DR   GO; GO:0008963; F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity; IEA:InterPro.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0003975; F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019408; P:dolichol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IMP:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0051259; P:protein oligomerization; ISS:UniProtKB.
DR   GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; IEA:Ensembl.
//
ID   GPVI_HUMAN              Reviewed;         339 AA.
AC   Q9HCN6; Q9HCN7; Q9UIF2;
DE   RecName: Full=Platelet glycoprotein VI;
DE            Short=GPVI;
DE   AltName: Full=Glycoprotein 6;
DE   Flags: Precursor;
GN   Name=GP6;
DR   GO; GO:0005518; F:collagen binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
//
ID   GPV_HUMAN               Reviewed;         560 AA.
AC   P40197; D1MER9;
DE   RecName: Full=Platelet glycoprotein V;
DE            Short=GPV;
DE   AltName: Full=Glycoprotein 5;
DE   AltName: CD_antigen=CD42d;
DE   Flags: Precursor;
GN   Name=GP5;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
//
ID   GPX1_HUMAN              Reviewed;         203 AA.
AC   P07203; E9PAS1; Q7Z5H1; Q9BW12;
DE   RecName: Full=Glutathione peroxidase 1;
DE            Short=GPx-1;
DE            Short=GSHPx-1;
DE            EC=1.11.1.9;
DE   AltName: Full=Cellular glutathione peroxidase;
GN   Name=GPX1;
DR   GO; GO:0043295; F:glutathione binding; IEA:Ensembl.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IDA:BHF-UCL.
DR   GO; GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:Ensembl.
DR   GO; GO:0008430; F:selenium binding; IEA:Ensembl.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0060055; P:angiogenesis involved in wound healing; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0045454; P:cell redox homeostasis; IDA:BHF-UCL.
DR   GO; GO:0001885; P:endothelial cell development; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:BHF-UCL.
DR   GO; GO:0060047; P:heart contraction; IMP:BHF-UCL.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051702; P:interaction with symbiont; IEA:Ensembl.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0051450; P:myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:BHF-UCL.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0018158; P:protein oxidation; IEA:Ensembl.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0040029; P:regulation of gene expression, epigenetic; IDA:BHF-UCL.
DR   GO; GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IMP:BHF-UCL.
DR   GO; GO:0006982; P:response to lipid hydroperoxide; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0010269; P:response to selenium ion; IMP:BHF-UCL.
DR   GO; GO:0009609; P:response to symbiotic bacterium; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0009410; P:response to xenobiotic stimulus; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
DR   GO; GO:0009650; P:UV protection; IMP:BHF-UCL.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   GPX2_HUMAN              Reviewed;         190 AA.
AC   P18283; Q6PJ52; Q8WWI7; Q9NRP9;
DE   RecName: Full=Glutathione peroxidase 2;
DE            Short=GPx-2;
DE            Short=GSHPx-2;
DE            EC=1.11.1.9;
DE   AltName: Full=Gastrointestinal glutathione peroxidase;
DE   AltName: Full=Glutathione peroxidase-gastrointestinal;
DE            Short=GPx-GI;
DE            Short=GSHPx-GI;
DE   AltName: Full=Glutathione peroxidase-related protein 2;
DE            Short=GPRP-2;
GN   Name=GPX2;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004602; F:glutathione peroxidase activity; TAS:Reactome.
DR   GO; GO:0051702; P:interaction with symbiont; IEA:Ensembl.
DR   GO; GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   GO; GO:0009609; P:response to symbiotic bacterium; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
//
ID   GPX3_HUMAN              Reviewed;         226 AA.
AC   P22352; O43787; Q86W78; Q9NZ74; Q9UEL1;
DE   RecName: Full=Glutathione peroxidase 3;
DE            Short=GPx-3;
DE            Short=GSHPx-3;
DE            EC=1.11.1.9;
DE   AltName: Full=Extracellular glutathione peroxidase;
DE   AltName: Full=Plasma glutathione peroxidase;
DE            Short=GPx-P;
DE            Short=GSHPx-P;
DE   Flags: Precursor;
GN   Name=GPX3; Synonyms=GPXP;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0008430; F:selenium binding; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; TAS:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; TAS:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0006982; P:response to lipid hydroperoxide; TAS:UniProtKB.
//
ID   GPX4_HUMAN              Reviewed;         197 AA.
AC   P36969; O43381; Q6PJ59; Q9UPK2;
DE   RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial;
DE            Short=PHGPx;
DE            EC=1.11.1.12;
DE   AltName: Full=Glutathione peroxidase 4;
DE            Short=GPx-4;
DE            Short=GSHPx-4;
DE   Flags: Precursor;
GN   Name=GPX4;
DR   GO; GO:0043295; F:glutathione binding; IEA:Ensembl.
DR   GO; GO:0004602; F:glutathione peroxidase activity; TAS:UniProtKB.
DR   GO; GO:0047066; F:phospholipid-hydroperoxide glutathione peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008430; F:selenium binding; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; IEA:Ensembl.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:Ensembl.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:Ensembl.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   GPX5_HUMAN              Reviewed;         221 AA.
AC   O75715; A1A4Y0;
DE   RecName: Full=Epididymal secretory glutathione peroxidase;
DE            EC=1.11.1.9;
DE   AltName: Full=Epididymis-specific glutathione peroxidase-like protein;
DE            Short=EGLP;
DE   AltName: Full=Glutathione peroxidase 5;
DE            Short=GPx-5;
DE            Short=GSHPx-5;
DE   Flags: Precursor;
GN   Name=GPX5;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   GPX6_HUMAN              Reviewed;         221 AA.
AC   P59796; Q4PJ17;
DE   RecName: Full=Glutathione peroxidase 6;
DE            Short=GPx-6;
DE            Short=GSHPx-6;
DE            EC=1.11.1.9;
DE   Flags: Precursor;
GN   Name=GPX6;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   GPX7_HUMAN              Reviewed;         187 AA.
AC   Q96SL4; O95337; Q5T501;
DE   RecName: Full=Glutathione peroxidase 7;
DE            Short=GPx-7;
DE            Short=GSHPx-7;
DE            EC=1.11.1.9;
DE   AltName: Full=CL683;
DE   Flags: Precursor;
GN   Name=GPX7; Synonyms=GPX6; ORFNames=UNQ469/PRO828;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004601; F:peroxidase activity; EXP:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   GPX8_HUMAN              Reviewed;         209 AA.
AC   Q8TED1;
DE   RecName: Full=Probable glutathione peroxidase 8;
DE            Short=GPx-8;
DE            Short=GSHPx-8;
DE            EC=1.11.1.9;
GN   Name=GPX8; ORFNames=UNQ847/PRO1785;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004601; F:peroxidase activity; EXP:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   GR6_HUMAN               Reviewed;         149 AA.
AC   O15544;
DE   RecName: Full=Protein GR6;
GN   Name=GR6; Synonyms=C3orf27;
//
ID   GRAA_HUMAN              Reviewed;         262 AA.
AC   P12544; A4PHN1; Q6IB36;
DE   RecName: Full=Granzyme A;
DE            EC=3.4.21.78;
DE   AltName: Full=CTL tryptase;
DE   AltName: Full=Cytotoxic T-lymphocyte proteinase 1;
DE   AltName: Full=Fragmentin-1;
DE   AltName: Full=Granzyme-1;
DE   AltName: Full=Hanukkah factor;
DE            Short=H factor;
DE            Short=HF;
DE   Flags: Precursor;
GN   Name=GZMA; Synonyms=CTLA3, HFSP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0032078; P:negative regulation of endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.
//
ID   GRAB_HUMAN              Reviewed;         247 AA.
AC   P10144; Q8N1D2; Q9UCC1;
DE   RecName: Full=Granzyme B;
DE            EC=3.4.21.79;
DE   AltName: Full=C11;
DE   AltName: Full=CTLA-1;
DE   AltName: Full=Cathepsin G-like 1;
DE            Short=CTSGL1;
DE   AltName: Full=Cytotoxic T-lymphocyte proteinase 2;
DE            Short=Lymphocyte protease;
DE   AltName: Full=Fragmentin-2;
DE   AltName: Full=Granzyme-2;
DE   AltName: Full=Human lymphocyte protein;
DE            Short=HLP;
DE   AltName: Full=SECT;
DE   AltName: Full=T-cell serine protease 1-3E;
DE   Flags: Precursor;
GN   Name=GZMB; Synonyms=CGL1, CSPB, CTLA1, GRB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0008626; P:granzyme-mediated apoptotic signaling pathway; IBA:RefGenome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   GRAH_HUMAN              Reviewed;         246 AA.
AC   P20718; G3V2C5; Q6XGZ0; Q6XGZ1;
DE   RecName: Full=Granzyme H;
DE            EC=3.4.21.-;
DE   AltName: Full=CCP-X;
DE   AltName: Full=Cathepsin G-like 2;
DE            Short=CTSGL2;
DE   AltName: Full=Cytotoxic T-lymphocyte proteinase;
DE   AltName: Full=Cytotoxic serine protease C;
DE            Short=CSP-C;
DE   Flags: Precursor;
GN   Name=GZMH; Synonyms=CGL2, CTSGL2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   GRAK_HUMAN              Reviewed;         264 AA.
AC   P49863; B2R563;
DE   RecName: Full=Granzyme K;
DE            EC=3.4.21.-;
DE   AltName: Full=Fragmentin-3;
DE   AltName: Full=Granzyme-3;
DE   AltName: Full=NK-tryptase-2;
DE            Short=NK-Tryp-2;
DE   Flags: Precursor;
GN   Name=GZMK; Synonyms=TRYP2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   GRAM2_HUMAN             Reviewed;         354 AA.
AC   Q8IUY3; B3KT68;
DE   RecName: Full=GRAM domain-containing protein 2;
GN   Name=GRAMD2;
//
ID   GRAM3_HUMAN             Reviewed;         432 AA.
AC   Q96HH9; B7Z1F2; B7Z3R1; B7Z6D8; B7Z8T2; D3DSZ3; Q9H753;
DE   RecName: Full=GRAM domain-containing protein 3;
DE   AltName: Full=HCV NS3-transactivated protein 2;
GN   Name=GRAMD3; Synonyms=NS3TP2;
//
ID   GRAM4_HUMAN             Reviewed;         578 AA.
AC   Q6IC98; A9IN51; A9IN57; Q68EN0; Q9UGE6; Q9Y4B9;
DE   RecName: Full=GRAM domain-containing protein 4;
DE   AltName: Full=Death-inducing protein;
GN   Name=GRAMD4; Synonyms=DIP, KIAA0767;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   GRAM_HUMAN              Reviewed;         257 AA.
AC   P51124;
DE   RecName: Full=Granzyme M;
DE            EC=3.4.21.-;
DE   AltName: Full=Met-1 serine protease;
DE            Short=Hu-Met-1;
DE   AltName: Full=Met-ase;
DE   AltName: Full=Natural killer cell granular protease;
DE   Flags: Precursor;
GN   Name=GZMM; Synonyms=MET1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   GRAN_HUMAN              Reviewed;         217 AA.
AC   P28676; B2R5X3; Q53TB5; Q59EP3;
DE   RecName: Full=Grancalcin;
GN   Name=GCA; Synonyms=GCL;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   GRAP1_HUMAN             Reviewed;         841 AA.
AC   Q4V328; A6NL78; Q3MJ75; Q4V327; Q4V330; Q5HYG1; Q6N046; Q96DH8;
AC   Q9NQ43; Q9ULQ3;
DE   RecName: Full=GRIP1-associated protein 1;
DE            Short=GRASP-1;
GN   Name=GRIPAP1; Synonyms=KIAA1167;
//
ID   GRAP2_HUMAN             Reviewed;         330 AA.
AC   O75791; O43726; Q9NRB7;
DE   RecName: Full=GRB2-related adapter protein 2;
DE   AltName: Full=Adapter protein GRID;
DE   AltName: Full=GRB-2-like protein;
DE            Short=GRB2L;
DE   AltName: Full=GRBLG;
DE   AltName: Full=GRBX;
DE   AltName: Full=Grf40 adapter protein;
DE            Short=Grf-40;
DE   AltName: Full=Growth factor receptor-binding protein;
DE   AltName: Full=Hematopoietic cell-associated adapter protein GrpL;
DE   AltName: Full=P38;
DE   AltName: Full=Protein GADS;
DE   AltName: Full=SH3-SH2-SH3 adapter Mona;
GN   Name=GRAP2; Synonyms=GADS, GRB2L, GRID;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   GRAPL_HUMAN             Reviewed;         118 AA.
AC   Q8TC17; B2RXI8;
DE   RecName: Full=GRB2-related adapter protein-like;
GN   Name=GRAPL;
//
ID   GRAP_HUMAN              Reviewed;         217 AA.
AC   Q13588;
DE   RecName: Full=GRB2-related adapter protein;
GN   Name=GRAP;
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
//
ID   GRASP_HUMAN             Reviewed;         395 AA.
AC   Q7Z6J2; Q6PIF8; Q7Z741;
DE   RecName: Full=General receptor for phosphoinositides 1-associated scaffold protein;
DE            Short=GRP1-associated scaffold protein;
GN   Name=GRASP;
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
//
ID   GRB10_HUMAN             Reviewed;         594 AA.
AC   Q13322; A4D258; A7VJ95; A8K0E6; D3DVM9; O00427; O00701; O75222;
AC   Q92606; Q92907; Q92948;
DE   RecName: Full=Growth factor receptor-bound protein 10;
DE   AltName: Full=GRB10 adapter protein;
DE   AltName: Full=Insulin receptor-binding protein Grb-IR;
GN   Name=GRB10; Synonyms=GRBIR, KIAA0207;
DR   GO; GO:0005158; F:insulin receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0046325; P:negative regulation of glucose import; ISS:BHF-UCL.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; ISS:BHF-UCL.
//
ID   GRB14_HUMAN             Reviewed;         540 AA.
AC   Q14449; Q7Z6I1;
DE   RecName: Full=Growth factor receptor-bound protein 14;
DE   AltName: Full=GRB14 adapter protein;
GN   Name=GRB14;
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GRB1L_HUMAN             Reviewed;        1923 AA.
AC   Q9C091; A4QN17; Q9H8F1;
DE   RecName: Full=GREB1-like protein;
GN   Name=GREB1L; Synonyms=C18orf6, KIAA1772;
//
ID   GRB2_HUMAN              Reviewed;         217 AA.
AC   P62993; P29354; Q14450; Q63057; Q63059;
DE   RecName: Full=Growth factor receptor-bound protein 2;
DE   AltName: Full=Adapter protein GRB2;
DE   AltName: Full=Protein Ash;
DE   AltName: Full=SH2/SH3 adapter GRB2;
GN   Name=GRB2; Synonyms=ASH;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.
DR   GO; GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IDA:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IMP:BHF-UCL.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   GRB7_HUMAN              Reviewed;         532 AA.
AC   Q14451; B2RAV1; B3KNL0; B3KWP9; B7WP75; J3KQM4; Q53YD3; Q92568;
AC   Q96DF9; Q9Y220;
DE   RecName: Full=Growth factor receptor-bound protein 7;
DE   AltName: Full=B47;
DE   AltName: Full=Epidermal growth factor receptor GRB-7;
DE   AltName: Full=GRB7 adapter protein;
GN   Name=GRB7;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0034063; P:stress granule assembly; ISS:UniProtKB.
//
ID   GRCR1_HUMAN             Reviewed;         290 AA.
AC   A8MXD5;
DE   RecName: Full=Glutaredoxin domain-containing cysteine-rich protein 1;
GN   Name=GRXCR1; Synonyms=DFNB25;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0060119; P:inner ear receptor cell development; ISS:UniProtKB.
DR   GO; GO:0060122; P:inner ear receptor stereocilium organization; ISS:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0048563; P:post-embryonic organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; ISS:UniProtKB.
DR   GO; GO:0060118; P:vestibular receptor cell development; ISS:UniProtKB.
//
ID   GRCR2_HUMAN             Reviewed;         248 AA.
AC   A6NFK2;
DE   RecName: Full=Glutaredoxin domain-containing cysteine-rich protein 2;
DE   AltName: Full=GRXCR1-like protein;
DE   AltName: Full=Glutaredoxin domain-containing cysteine-rich protein 1-like protein;
GN   Name=GRXCR2;
//
ID   GRD2I_HUMAN             Reviewed;        1211 AA.
AC   A4D2P6;
DE   RecName: Full=Delphilin;
DE   AltName: Full=Glutamate receptor, ionotropic, delta 2-interacting protein 1;
GN   Name=GRID2IP;
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
//
ID   GRDN_HUMAN              Reviewed;        1871 AA.
AC   Q3V6T2; A1IGE7; B7ZM78; C9JG83; Q53SF1; Q581G3; Q5HYD0; Q7Z339;
AC   Q7Z3C5;
DE   RecName: Full=Girdin;
DE   AltName: Full=Akt phosphorylation enhancer;
DE            Short=APE;
DE   AltName: Full=Coiled-coil domain-containing protein 88A;
DE   AltName: Full=G alpha-interacting vesicle-associated protein;
DE            Short=GIV;
DE   AltName: Full=Girders of actin filament;
DE   AltName: Full=Hook-related protein 1;
DE            Short=HkRP1;
GN   Name=CCDC88A; Synonyms=APE, GRDN, KIAA1212;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0043422; F:protein kinase B binding; IPI:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; ISS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; ISS:UniProtKB.
DR   GO; GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0031929; P:TOR signaling; ISS:UniProtKB.
//
ID   GREB1_HUMAN             Reviewed;        1949 AA.
AC   Q4ZG55; A6NHD0; A6NKN0; B5MDA9; O60321; Q7Z5S2; Q9H2Q6; Q9H2Q7;
AC   Q9H2Q8;
DE   RecName: Full=Protein GREB1;
DE   AltName: Full=Gene regulated in breast cancer 1 protein;
GN   Name=GREB1; Synonyms=KIAA0575;
//
ID   GREM2_HUMAN             Reviewed;         168 AA.
AC   Q9H772; Q86UD9;
DE   RecName: Full=Gremlin-2;
DE   AltName: Full=Cysteine knot superfamily 1, BMP antagonist 2;
DE   AltName: Full=DAN domain family member 3;
DE   AltName: Full=Protein related to DAN and cerberus;
DE   Flags: Precursor;
GN   Name=GREM2; Synonyms=CKTSF1B2, DAND3, PRDC;
DR   GO; GO:0008201; F:heparin binding; ISS:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0010172; P:embryonic body morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060300; P:regulation of cytokine activity; ISS:UniProtKB.
//
ID   GREM1_HUMAN             Reviewed;         184 AA.
AC   O60565; Q52LV3; Q8N914; Q8N936;
DE   RecName: Full=Gremlin-1;
DE   AltName: Full=Cell proliferation-inducing gene 2 protein;
DE   AltName: Full=Cysteine knot superfamily 1, BMP antagonist 1;
DE   AltName: Full=DAN domain family member 2;
DE   AltName: Full=Down-regulated in Mos-transformed cells protein;
DE   AltName: Full=Increased in high glucose protein 2;
DE            Short=IHG-2;
DE   Flags: Precursor;
GN   Name=GREM1; Synonyms=CKTSF1B1, DAND2, DRM; ORFNames=PIG2;
DR   GO; GO:0036122; F:BMP binding; ISS:BHF-UCL.
DR   GO; GO:0016015; F:morphogen activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048018; F:receptor agonist activity; ISS:BHF-UCL.
DR   GO; GO:0030297; F:transmembrane receptor protein tyrosine kinase activator activity; ISS:BHF-UCL.
DR   GO; GO:0043184; F:vascular endothelial growth factor receptor 2 binding; ISS:BHF-UCL.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; ISS:GOC.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0000902; P:cell morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:BHF-UCL.
DR   GO; GO:0048263; P:determination of dorsal identity; IMP:BHF-UCL.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:1900158; P:negative regulation of bone mineralization involved in bone maturation; IMP:BHF-UCL.
DR   GO; GO:0046851; P:negative regulation of bone remodeling; IMP:BHF-UCL.
DR   GO; GO:1900155; P:negative regulation of bone trabecula formation; IMP:BHF-UCL.
DR   GO; GO:0090191; P:negative regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0090027; P:negative regulation of monocyte chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0090291; P:negative regulation of osteoclast proliferation; IMP:BHF-UCL.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:2000727; P:positive regulation of cardiac muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:1900086; P:positive regulation of peptidyl-tyrosine autophosphorylation; ISS:BHF-UCL.
DR   GO; GO:2000273; P:positive regulation of receptor activity; ISS:BHF-UCL.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; ISS:BHF-UCL.
DR   GO; GO:0051973; P:positive regulation of telomerase activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0003257; P:positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; IMP:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; ISS:BHF-UCL.
DR   GO; GO:0060676; P:ureteric bud formation; IEA:Ensembl.
//
ID   GRHL1_HUMAN             Reviewed;         618 AA.
AC   Q9NZI5; A6NLA4; B2R7E4; B5MEC2; Q53T93; Q6NWN7; Q6NWN8; Q6NWN9;
AC   Q8NI33;
DE   RecName: Full=Grainyhead-like protein 1 homolog;
DE   AltName: Full=Mammalian grainyhead;
DE   AltName: Full=NH32;
DE   AltName: Full=Transcription factor CP2-like 2;
DE   AltName: Full=Transcription factor LBP-32;
GN   Name=GRHL1; Synonyms=LBP32, MGR, TFCP2L2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GRHL3_HUMAN             Reviewed;         626 AA.
AC   Q8TE85; A2A297; B2RCL1; G3XAF0; Q5TH78; Q86Y06; Q8N407;
DE   RecName: Full=Grainyhead-like protein 3 homolog;
DE   AltName: Full=Sister of mammalian grainyhead;
DE   AltName: Full=Transcription factor CP2-like 4;
GN   Name=GRHL3; Synonyms=SOM, TFCP2L4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0001736; P:establishment of planar polarity; IEA:Ensembl.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IGI:MGI.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   GRHL2_HUMAN             Reviewed;         625 AA.
AC   Q6ISB3; A1L303; Q6NT03; Q9H8B8;
DE   RecName: Full=Grainyhead-like protein 2 homolog;
DE   AltName: Full=Brother of mammalian grainyhead;
DE   AltName: Full=Transcription factor CP2-like 3;
GN   Name=GRHL2; Synonyms=BOM, TFCP2L3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GRHPR_HUMAN             Reviewed;         328 AA.
AC   Q9UBQ7; Q5T945; Q9H3E9; Q9UKX1;
DE   RecName: Full=Glyoxylate reductase/hydroxypyruvate reductase;
DE            EC=1.1.1.79;
DE            EC=1.1.1.81;
GN   Name=GRHPR; Synonyms=GLXR; ORFNames=MSTP035;
DR   GO; GO:0031406; F:carboxylic acid binding; IEA:Ensembl.
DR   GO; GO:0008465; F:glycerate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0030267; F:glyoxylate reductase (NADP) activity; IDA:UniProtKB.
DR   GO; GO:0016618; F:hydroxypyruvate reductase activity; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; TAS:UniProtKB.
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0043648; P:dicarboxylic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; IMP:UniProtKB.
DR   GO; GO:0046487; P:glyoxylate metabolic process; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; NAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GRIA1_HUMAN             Reviewed;         906 AA.
AC   P42261; B7Z2S0; B7Z2W8; B7Z3F6; B7Z9G9; D3DQI4; E7ESV8; Q2NKM6;
DE   RecName: Full=Glutamate receptor 1;
DE            Short=GluR-1;
DE   AltName: Full=AMPA-selective glutamate receptor 1;
DE   AltName: Full=GluR-A;
DE   AltName: Full=GluR-K1;
DE   AltName: Full=Glutamate receptor ionotropic, AMPA 1;
DE            Short=GluA1;
DE   Flags: Precursor;
GN   Name=GRIA1; Synonyms=GLUH1, GLUR1;
DR   GuidetoPHARMACOLOGY; 444; -.
DR   GO; GO:0004971; F:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0008066; F:glutamate receptor activity; TAS:ProtInc.
DR   GO; GO:0030165; F:PDZ domain binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0031623; P:receptor internalization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   GRIA2_HUMAN             Reviewed;         883 AA.
AC   P42262; Q96FP6;
DE   RecName: Full=Glutamate receptor 2;
DE            Short=GluR-2;
DE   AltName: Full=AMPA-selective glutamate receptor 2;
DE   AltName: Full=GluR-B;
DE   AltName: Full=GluR-K2;
DE   AltName: Full=Glutamate receptor ionotropic, AMPA 2;
DE            Short=GluA2;
DE   Flags: Precursor;
GN   Name=GRIA2; Synonyms=GLUR2;
DR   GuidetoPHARMACOLOGY; 445; -.
DR   GO; GO:0004971; F:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0004970; F:ionotropic glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   GRIA3_HUMAN             Reviewed;         894 AA.
AC   P42263; D3DTF1; Q4VXD5; Q4VXD6; Q9HDA0; Q9HDA1; Q9HDA2; Q9P0H1;
DE   RecName: Full=Glutamate receptor 3;
DE            Short=GluR-3;
DE   AltName: Full=AMPA-selective glutamate receptor 3;
DE   AltName: Full=GluR-C;
DE   AltName: Full=GluR-K3;
DE   AltName: Full=Glutamate receptor ionotropic, AMPA 3;
DE            Short=GluA3;
DE   Flags: Precursor;
GN   Name=GRIA3; Synonyms=GLUR3, GLURC;
DR   GuidetoPHARMACOLOGY; 446; -.
DR   GO; GO:0004971; F:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GRIA4_HUMAN             Reviewed;         902 AA.
AC   P48058; Q86XE8;
DE   RecName: Full=Glutamate receptor 4;
DE            Short=GluR-4;
DE            Short=GluR4;
DE   AltName: Full=AMPA-selective glutamate receptor 4;
DE   AltName: Full=GluR-D;
DE   AltName: Full=Glutamate receptor ionotropic, AMPA 4;
DE            Short=GluA4;
DE   Flags: Precursor;
GN   Name=GRIA4; Synonyms=GLUR4;
DR   GuidetoPHARMACOLOGY; 447; -.
DR   GO; GO:0004971; F:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0004970; F:ionotropic glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GRID1_HUMAN             Reviewed;        1009 AA.
AC   Q9ULK0; B3KXD5; Q8IXT3;
DE   RecName: Full=Glutamate receptor ionotropic, delta-1;
DE            Short=GluD1;
DE            Short=GluR delta-1 subunit;
DE   Flags: Precursor;
GN   Name=GRID1; Synonyms=KIAA1220;
DR   GuidetoPHARMACOLOGY; 448; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0004970; F:ionotropic glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0035176; P:social behavior; ISS:UniProt.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   GRID2_HUMAN             Reviewed;        1007 AA.
AC   O43424; E9PH24; Q4KKU8; Q4KKU9; Q4KKV0; Q59FZ1;
DE   RecName: Full=Glutamate receptor ionotropic, delta-2;
DE            Short=GluD2;
DE            Short=GluR delta-2 subunit;
DE   Flags: Precursor;
GN   Name=GRID2; Synonyms=GLURD2;
DR   GuidetoPHARMACOLOGY; 449; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0008066; F:glutamate receptor activity; TAS:ProtInc.
DR   GO; GO:0004970; F:ionotropic glutamate receptor activity; IEA:InterPro.
DR   GO; GO:0030165; F:PDZ domain binding; ISS:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0034613; P:cellular protein localization; ISS:BHF-UCL.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GRIFN_HUMAN             Reviewed;         148 AA.
AC   A4D1Z8;
DE   RecName: Full=Putative grifin;
DE   AltName: Full=Galectin-related inter-fiber protein;
GN   Name=GRIFIN;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   GRIK1_HUMAN             Reviewed;         918 AA.
AC   P39086; Q13001; Q86SU9;
DE   RecName: Full=Glutamate receptor ionotropic, kainate 1;
DE            Short=GluK1;
DE   AltName: Full=Excitatory amino acid receptor 3;
DE            Short=EAA3;
DE   AltName: Full=Glutamate receptor 5;
DE            Short=GluR-5;
DE            Short=GluR5;
DE   Flags: Precursor;
GN   Name=GRIK1; Synonyms=GLUR5;
DR   GuidetoPHARMACOLOGY; 450; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0014054; P:positive regulation of gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GRIK2_HUMAN             Reviewed;         908 AA.
AC   Q13002; A6NMY9; B5MCV0; D7RWZ3; D7RWZ4; D7RWZ5; D7RWZ6; D7RWZ7;
AC   Q8WWS1; Q96KS6; Q96KS7; Q96KS8;
DE   RecName: Full=Glutamate receptor ionotropic, kainate 2;
DE            Short=GluK2;
DE   AltName: Full=Excitatory amino acid receptor 4;
DE            Short=EAA4;
DE   AltName: Full=Glutamate receptor 6;
DE            Short=GluR-6;
DE            Short=GluR6;
DE   Flags: Precursor;
GN   Name=GRIK2; Synonyms=GLUR6;
DR   GuidetoPHARMACOLOGY; 451; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IMP:UniProtKB.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:UniProtKB.
DR   GO; GO:0050804; P:regulation of synaptic transmission; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   GRIK3_HUMAN             Reviewed;         919 AA.
AC   Q13003; B1AMS6; Q13004; Q16136;
DE   RecName: Full=Glutamate receptor ionotropic, kainate 3;
DE            Short=GluK3;
DE   AltName: Full=Excitatory amino acid receptor 5;
DE            Short=EAA5;
DE   AltName: Full=Glutamate receptor 7;
DE            Short=GluR-7;
DE            Short=GluR7;
DE   Flags: Precursor;
GN   Name=GRIK3; Synonyms=GLUR7;
DR   GuidetoPHARMACOLOGY; 452; -.
DR   GO; GO:0001640; F:adenylate cyclase inhibiting G-protein coupled glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0008066; F:glutamate receptor activity; TAS:UniProtKB.
DR   GO; GO:0004970; F:ionotropic glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; ISS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   GRIK4_HUMAN             Reviewed;         956 AA.
AC   Q16099; A8K9L1;
DE   RecName: Full=Glutamate receptor ionotropic, kainate 4;
DE            Short=GluK4;
DE   AltName: Full=Excitatory amino acid receptor 1;
DE            Short=EAA1;
DE   AltName: Full=Glutamate receptor KA-1;
DE            Short=KA1;
DE   Flags: Precursor;
GN   Name=GRIK4; Synonyms=GRIK;
DR   GuidetoPHARMACOLOGY; 453; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0015277; F:kainate selective glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0031960; P:response to corticosteroid; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   GRIK5_HUMAN             Reviewed;         980 AA.
AC   Q16478; Q8WWG8;
DE   RecName: Full=Glutamate receptor ionotropic, kainate 5;
DE            Short=GluK5;
DE   AltName: Full=Excitatory amino acid receptor 2;
DE            Short=EAA2;
DE   AltName: Full=Glutamate receptor KA-2;
DE            Short=KA2;
DE   Flags: Precursor;
GN   Name=GRIK5; Synonyms=GRIK2;
DR   GuidetoPHARMACOLOGY; 454; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0015277; F:kainate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0051649; P:establishment of localization in cell; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GOC.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:GOC.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006621; P:protein retention in ER lumen; IEA:Ensembl.
DR   GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0031630; P:regulation of synaptic vesicle fusion to presynaptic membrane; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   GRIN1_HUMAN             Reviewed;        1008 AA.
AC   Q7Z2K8; C9JM70; Q8ND74; Q96PZ4;
DE   RecName: Full=G protein-regulated inducer of neurite outgrowth 1;
DE            Short=GRIN1;
GN   Name=GPRIN1; Synonyms=KIAA1893;
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
//
ID   GRIN2_HUMAN             Reviewed;         458 AA.
AC   O60269; Q5SVF0;
DE   RecName: Full=G protein-regulated inducer of neurite outgrowth 2;
DE            Short=GRIN2;
GN   Name=GPRIN2; Synonyms=KIAA0514;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GRIN3_HUMAN             Reviewed;         776 AA.
AC   Q6ZVF9; Q8IVE4;
DE   RecName: Full=G protein-regulated inducer of neurite outgrowth 3;
DE            Short=GRIN3;
GN   Name=GPRIN3; Synonyms=KIAA2027;
//
ID   GRIP1_HUMAN             Reviewed;        1128 AA.
AC   Q9Y3R0; C9JT59; Q1RLM0;
DE   RecName: Full=Glutamate receptor-interacting protein 1;
DE            Short=GRIP-1;
GN   Name=GRIP1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; TAS:AgBase.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GRIP2_HUMAN             Reviewed;        1043 AA.
AC   Q9C0E4; Q8TEH9; Q9H7H3;
DE   RecName: Full=Glutamate receptor-interacting protein 2;
DE            Short=GRIP-2;
GN   Name=GRIP2; Synonyms=KIAA1719;
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   GRK4_HUMAN              Reviewed;         578 AA.
AC   P32298; O00641; O00642; Q13293; Q13294; Q13295; Q14453; Q14725;
AC   Q15313; Q15314; Q15315; Q15316; Q17RH6; Q53EQ8;
DE   RecName: Full=G protein-coupled receptor kinase 4;
DE            EC=2.7.11.16;
DE   AltName: Full=G protein-coupled receptor kinase GRK4;
DE   AltName: Full=ITI1;
GN   Name=GRK4; Synonyms=GPRK2L, GPRK4;
DR   GuidetoPHARMACOLOGY; 1468; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050254; F:rhodopsin kinase activity; IEA:Ensembl.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IEA:Ensembl.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   GRK5_HUMAN              Reviewed;         590 AA.
AC   P34947; D3DRD0; Q5T059;
DE   RecName: Full=G protein-coupled receptor kinase 5;
DE            EC=2.7.11.16;
DE   AltName: Full=G protein-coupled receptor kinase GRK5;
GN   Name=GRK5; Synonyms=GPRK5;
DR   GuidetoPHARMACOLOGY; 1469; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   GRK6_HUMAN              Reviewed;         576 AA.
AC   P43250; O60541; Q13652;
DE   RecName: Full=G protein-coupled receptor kinase 6;
DE            EC=2.7.11.16;
DE   AltName: Full=G protein-coupled receptor kinase GRK6;
GN   Name=GRK6; Synonyms=GPRK6;
DR   GuidetoPHARMACOLOGY; 1470; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   GRK7_HUMAN              Reviewed;         553 AA.
AC   Q8WTQ7;
DE   RecName: Full=G protein-coupled receptor kinase 7;
DE            EC=2.7.11.14;
DE            EC=2.7.11.16;
DE   AltName: Full=G protein-coupled receptor kinase GRK7;
DE   Flags: Precursor;
GN   Name=GRK7; Synonyms=GPRK7;
DR   GuidetoPHARMACOLOGY; 1471; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050254; F:rhodopsin kinase activity; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   GRL1A_HUMAN             Reviewed;         368 AA.
AC   P0CAP2; Q6EER8; Q6EES2; Q6EEV3; Q6EF00; Q6EF01; Q6EF02; Q6EF46;
AC   Q6EFN8; Q6EM48; Q6K046; Q6K050; Q6K051; Q6ZQZ3; Q8NC58; Q8NCF3;
AC   Q96DI5; Q96JB7; Q96NF5; Q9Y3V6;
DE   RecName: Full=DNA-directed RNA polymerase II subunit GRINL1A;
DE   AltName: Full=DNA-directed RNA polymerase II subunit M;
DE   AltName: Full=Glutamate receptor-like protein 1A;
GN   Name=POLR2M; Synonyms=GRINL1A;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051685; P:maintenance of ER location; IEA:Ensembl.
//
ID   GRM1A_HUMAN             Reviewed;         724 AA.
AC   Q96CP6; A6NKY7; Q8NC77; Q9P1Z5;
DE   RecName: Full=GRAM domain-containing protein 1A;
GN   Name=GRAMD1A; Synonyms=KIAA1533;
//
ID   GRM1B_HUMAN             Reviewed;         738 AA.
AC   Q3KR37; Q6UW85; Q9ULL9;
DE   RecName: Full=GRAM domain-containing protein 1B;
GN   Name=GRAMD1B; Synonyms=KIAA1201; ORFNames=UNQ3032/PRO9834;
//
ID   GRM1C_HUMAN             Reviewed;         662 AA.
AC   Q8IYS0; A8K9Y1; A8KA99; Q6AW94; Q6UWN1; Q8N6S0; Q9UF46;
DE   RecName: Full=GRAM domain-containing protein 1C;
GN   Name=GRAMD1C; ORFNames=UNQ2543/PRO6095;
//
ID   GRM1_HUMAN              Reviewed;        1194 AA.
AC   Q13255; B9EG79; Q13256; Q14757; Q14758; Q5VTF7; Q5VTF8; Q9NU10;
AC   Q9UGS9; Q9UGT0;
DE   RecName: Full=Metabotropic glutamate receptor 1;
DE            Short=mGluR1;
DE   Flags: Precursor;
GN   Name=GRM1; Synonyms=GPRC1A, MGLUR1;
DR   GuidetoPHARMACOLOGY; 289; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GRM2_HUMAN              Reviewed;         872 AA.
AC   Q14416; B0M0K7; Q14CU5; Q52MC6; Q9H3N6;
DE   RecName: Full=Metabotropic glutamate receptor 2;
DE            Short=mGluR2;
DE   Flags: Precursor;
GN   Name=GRM2; Synonyms=GPRC1B, MGLUR2;
DR   GuidetoPHARMACOLOGY; 290; -.
DR   GO; GO:0005246; F:calcium channel regulator activity; IBA:RefGenome.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; TAS:UniProtKB.
DR   GO; GO:0001641; F:group II metabotropic glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0014047; P:glutamate secretion; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GRM3_HUMAN              Reviewed;         879 AA.
AC   Q14832; Q2PNZ6; Q75MV4; Q75N17; Q86YG6; Q8TBH9;
DE   RecName: Full=Metabotropic glutamate receptor 3;
DE            Short=mGluR3;
DE   Flags: Precursor;
GN   Name=GRM3; Synonyms=GPRC1C, MGLUR3;
DR   GuidetoPHARMACOLOGY; 291; -.
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; TAS:UniProtKB.
DR   GO; GO:0001641; F:group II metabotropic glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GRM4_HUMAN              Reviewed;         912 AA.
AC   Q14833; B3KVL9; B7Z1T9; B7Z1U6; F5GXM5; Q5SZ84; Q6ZMQ2;
DE   RecName: Full=Metabotropic glutamate receptor 4;
DE            Short=mGluR4;
DE   Flags: Precursor;
GN   Name=GRM4; Synonyms=GPRC1D, MGLUR4;
DR   GuidetoPHARMACOLOGY; 292; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IMP:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; IMP:UniProtKB.
DR   GO; GO:0001642; F:group III metabotropic glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEP:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; TAS:UniProtKB.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GRM5_HUMAN              Reviewed;        1212 AA.
AC   P41594; Q6J164;
DE   RecName: Full=Metabotropic glutamate receptor 5;
DE            Short=mGluR5;
DE   Flags: Precursor;
GN   Name=GRM5; Synonyms=GPRC1E, MGLUR5;
DR   GuidetoPHARMACOLOGY; 293; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IEA:Ensembl.
DR   GO; GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0040013; P:negative regulation of locomotion; IEA:Ensembl.
DR   GO; GO:0007206; P:phospholipase C-activating G-protein coupled glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   GRM6_HUMAN              Reviewed;         877 AA.
AC   O15303;
DE   RecName: Full=Metabotropic glutamate receptor 6;
DE            Short=mGluR6;
DE   Flags: Precursor;
GN   Name=GRM6; Synonyms=GPRC1F, MGLUR6;
DR   GuidetoPHARMACOLOGY; 294; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; IMP:UniProtKB.
DR   GO; GO:0001642; F:group III metabotropic glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProtKB.
DR   GO; GO:0009584; P:detection of visible light; TAS:ProtInc.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IMP:UniProtKB.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   GRM7_HUMAN              Reviewed;         915 AA.
AC   Q14831; Q8NFS2; Q8NFS3; Q8NFS4;
DE   RecName: Full=Metabotropic glutamate receptor 7;
DE            Short=mGluR7;
DE   Flags: Precursor;
GN   Name=GRM7; Synonyms=GPRC1G, MGLUR7;
DR   GuidetoPHARMACOLOGY; 295; -.
DR   GO; GO:0010855; F:adenylate cyclase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005246; F:calcium channel regulator activity; IBA:RefGenome.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0016595; F:glutamate binding; IDA:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0001642; F:group III metabotropic glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; NAS:UniProtKB.
DR   GO; GO:0070905; F:serine binding; IDA:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0001661; P:conditioned taste aversion; IEA:Ensembl.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; ISS:UniProtKB.
DR   GO; GO:0031279; P:regulation of cyclase activity; IDA:GOC.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0007614; P:short-term memory; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IDA:UniProtKB.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   GRM8_HUMAN              Reviewed;         908 AA.
AC   O00222; A4D0Y3; B0FZ74; B0M0L0; O15493; O95945; O95946; Q3MIV9;
AC   Q52M02; Q6J165;
DE   RecName: Full=Metabotropic glutamate receptor 8;
DE            Short=mGluR8;
DE   Flags: Precursor;
GN   Name=GRM8; Synonyms=GPRC1H, MGLUR8;
DR   GuidetoPHARMACOLOGY; 296; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IMP:UniProtKB.
DR   GO; GO:0008066; F:glutamate receptor activity; IMP:UniProtKB.
DR   GO; GO:0001642; F:group III metabotropic glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0007196; P:adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   GRN_HUMAN               Reviewed;         593 AA.
AC   P28799; D3DX55; P23781; P23782; P23783; P23784; Q53HQ8; Q53Y88;
AC   Q540U8; Q9BWE7; Q9H8S1; Q9UCH0;
DE   RecName: Full=Granulins;
DE   AltName: Full=Proepithelin;
DE            Short=PEPI;
DE   Contains:
DE     RecName: Full=Acrogranin;
DE     AltName: Full=Glycoprotein of 88 Kda;
DE     AltName: Full=Progranulin;
DE   Contains:
DE     RecName: Full=Paragranulin;
DE   Contains:
DE     RecName: Full=Granulin-1;
DE     AltName: Full=Granulin G;
DE   Contains:
DE     RecName: Full=Granulin-2;
DE     AltName: Full=Granulin F;
DE   Contains:
DE     RecName: Full=Granulin-3;
DE     AltName: Full=Granulin B;
DE   Contains:
DE     RecName: Full=Granulin-4;
DE     AltName: Full=Granulin A;
DE   Contains:
DE     RecName: Full=Granulin-5;
DE     AltName: Full=Granulin C;
DE   Contains:
DE     RecName: Full=Granulin-6;
DE     AltName: Full=Granulin D;
DE   Contains:
DE     RecName: Full=Granulin-7;
DE     AltName: Full=Granulin E;
DE   Flags: Precursor;
GN   Name=GRN;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   GROA_HUMAN              Reviewed;         107 AA.
AC   P09341; Q9UCR7;
DE   RecName: Full=Growth-regulated alpha protein;
DE   AltName: Full=C-X-C motif chemokine 1;
DE   AltName: Full=GRO-alpha(1-73);
DE   AltName: Full=Melanoma growth stimulatory activity;
DE            Short=MGSA;
DE   AltName: Full=Neutrophil-activating protein 3;
DE            Short=NAP-3;
DE   Contains:
DE     RecName: Full=GRO-alpha(4-73);
DE   Contains:
DE     RecName: Full=GRO-alpha(5-73);
DE   Contains:
DE     RecName: Full=GRO-alpha(6-73);
DE   Flags: Precursor;
GN   Name=CXCL1; Synonyms=GRO, GRO1, GROA, MGSA, SCYB1;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GRP1_HUMAN              Reviewed;         797 AA.
AC   O95267; Q56CZ0; Q58G75; Q59HB1; Q5I3A8; Q6GV31; Q6NX39; Q7LDG6;
AC   Q9UI94; Q9UNN9;
DE   RecName: Full=RAS guanyl-releasing protein 1;
DE   AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor II;
DE            Short=CalDAG-GEFII;
DE   AltName: Full=Ras guanyl-releasing protein;
GN   Name=RASGRP1; Synonyms=RASGRP;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043303; P:mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0014066; P:regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0032252; P:secretory granule localization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IEA:Ensembl.
//
ID   GRP2_HUMAN              Reviewed;         609 AA.
AC   Q7LDG7; A6NDC7; O00538; Q9UL65;
DE   RecName: Full=RAS guanyl-releasing protein 2;
DE   AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor I;
DE            Short=CalDAG-GEFI;
DE   AltName: Full=Cdc25-like protein;
DE            Short=hCDC25L;
DE   AltName: Full=F25B3.3 kinase-like protein;
GN   Name=RASGRP2; Synonyms=CDC25L, MCG7;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   GRP3_HUMAN              Reviewed;         690 AA.
AC   Q8IV61; D6W583; O94931; Q53SD7;
DE   RecName: Full=Ras guanyl-releasing protein 3;
DE   AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor III;
DE   AltName: Full=Guanine nucleotide exchange factor for Rap1;
GN   Name=RASGRP3; Synonyms=GRP3, KIAA0846;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0046582; F:Rap GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; TAS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; NAS:UniProtKB.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; IDA:GOC.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:UniProtKB.
//
ID   GRP4_HUMAN              Reviewed;         673 AA.
AC   Q8TDF6; A6H8M4; C0LTP2; C0LTP3; C0LTP4; C0LTP5; C0LTP7; C9J416;
AC   C9JHZ1; Q8N858; Q96QN5; Q96QN6; Q96QN7;
DE   RecName: Full=RAS guanyl-releasing protein 4;
GN   Name=RASGRP4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0019992; F:diacylglycerol binding; TAS:UniProtKB.
DR   GO; GO:0030742; F:GTP-dependent protein binding; NAS:UniProtKB.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; NAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; NAS:UniProtKB.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; IDA:GOC.
DR   GO; GO:0009991; P:response to extracellular stimulus; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
//
ID   GRP75_HUMAN             Reviewed;         679 AA.
AC   P38646; B2RCM1; P30036; P31932; Q1HB43; Q53H23; Q6GU03; Q9BWB7;
AC   Q9UC56;
DE   RecName: Full=Stress-70 protein, mitochondrial;
DE   AltName: Full=75 kDa glucose-regulated protein;
DE            Short=GRP-75;
DE   AltName: Full=Heat shock 70 kDa protein 9;
DE   AltName: Full=Mortalin;
DE            Short=MOT;
DE   AltName: Full=Peptide-binding protein 74;
DE            Short=PBP74;
DE   Flags: Precursor;
GN   Name=HSPA9; Synonyms=GRP75, HSPA9B, mt-HSP70;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   GRP78_HUMAN             Reviewed;         654 AA.
AC   P11021; B0QZ61; Q2EF78; Q9NPF1; Q9UK02;
DE   RecName: Full=78 kDa glucose-regulated protein;
DE            Short=GRP-78;
DE   AltName: Full=Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78;
DE   AltName: Full=Heat shock 70 kDa protein 5;
DE   AltName: Full=Immunoglobulin heavy chain-binding protein;
DE            Short=BiP;
DE   Flags: Precursor;
GN   Name=HSPA5; Synonyms=GRP78;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0051087; F:chaperone binding; TAS:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0051787; F:misfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0021589; P:cerebellum structural organization; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:BHF-UCL.
DR   GO; GO:0006983; P:ER overload response; IEA:Ensembl.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; TAS:BHF-UCL.
DR   GO; GO:0035437; P:maintenance of protein localization in endoplasmic reticulum; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0060904; P:regulation of protein folding in endoplasmic reticulum; TAS:BHF-UCL.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   GRPE1_HUMAN             Reviewed;         217 AA.
AC   Q9HAV7; B2R783; Q549M6;
DE   RecName: Full=GrpE protein homolog 1, mitochondrial;
DE   AltName: Full=HMGE;
DE   AltName: Full=Mt-GrpE#1;
DE   Flags: Precursor;
GN   Name=GRPEL1; Synonyms=GREPEL1;
DR   GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   GRPE2_HUMAN             Reviewed;         225 AA.
AC   Q8TAA5; Q49AJ6;
DE   RecName: Full=GrpE protein homolog 2, mitochondrial;
DE   AltName: Full=Mt-GrpE#2;
DE   Flags: Precursor;
GN   Name=GRPEL2;
DR   GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   GRPL2_HUMAN             Reviewed;         344 AA.
AC   Q4G1C9; Q6MZS1; Q8N6N0; Q8NA43;
DE   RecName: Full=GLIPR1-like protein 2;
GN   Name=GLIPR1L2;
//
ID   GRPR_HUMAN              Reviewed;         384 AA.
AC   P30550; B2R910;
DE   RecName: Full=Gastrin-releasing peptide receptor;
DE            Short=GRP-R;
DE   AltName: Full=GRP-preferring bombesin receptor;
GN   Name=GRPR;
DR   GuidetoPHARMACOLOGY; 39; -.
DR   GO; GO:0004946; F:bombesin receptor activity; IEA:InterPro.
DR   GO; GO:0008528; F:G-protein coupled peptide receptor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
//
ID   GRP_HUMAN               Reviewed;         148 AA.
AC   P07492; P07491; P81553; Q14454; Q53YA0; Q9BSY7;
DE   RecName: Full=Gastrin-releasing peptide;
DE            Short=GRP;
DE   Contains:
DE     RecName: Full=Neuromedin-C;
DE     AltName: Full=GRP-10;
DE   Flags: Precursor;
GN   Name=GRP;
DR   GO; GO:0005184; F:neuropeptide hormone activity; IDA:MGI.
DR   GO; GO:0005102; F:receptor binding; NAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   GRSF1_HUMAN             Reviewed;         480 AA.
AC   Q12849; B3KPW0; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2;
DE   RecName: Full=G-rich sequence factor 1;
DE            Short=GRSF-1;
DE   Flags: Precursor;
GN   Name=GRSF1;
DR   GO; GO:0003729; F:mRNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   GRTP1_HUMAN             Reviewed;         336 AA.
AC   Q5TC63; B9A6K2; Q2M232; Q5TC64; Q66K26; Q6P659; Q8N528; Q9H695;
DE   RecName: Full=Growth hormone-regulated TBC protein 1;
DE   AltName: Full=TBC1 domain family member 6;
GN   Name=GRTP1; Synonyms=TBC1D6;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   GRWD1_HUMAN             Reviewed;         446 AA.
AC   Q9BQ67; Q8TF59;
DE   RecName: Full=Glutamate-rich WD repeat-containing protein 1;
GN   Name=GRWD1; Synonyms=GRWD, KIAA1942, WDR28;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   GSAP_HUMAN              Reviewed;         854 AA.
AC   A4D1B5; A4D1B6; Q3MJC0; Q8ND73; Q9UMH3; Q9Y4L9;
DE   RecName: Full=Gamma-secretase-activating protein;
DE            Short=GSAP;
DE   AltName: Full=Protein pigeon homolog;
DE   Contains:
DE     RecName: Full=Gamma-secretase-activating protein 16 kDa C-terminal form;
DE              Short=GSAP-16K;
GN   Name=GSAP; Synonyms=PION;
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:UniProtKB.
DR   GO; GO:0034205; P:beta-amyloid formation; IDA:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IDA:UniProtKB.
//
ID   GSAS1_HUMAN             Reviewed;         163 AA.
AC   Q9NRJ2;
DE   RecName: Full=Putative uncharacterized protein GSN-AS1;
DE   AltName: Full=GSN antisense RNA 1;
DE   AltName: Full=GSN antisense gene protein 1;
DE   AltName: Full=Protein MOST-2;
GN   Name=GSN-AS1; Synonyms=C9orf31, MOST2;
//
ID   GSAML_HUMAN             Reviewed;         135 AA.
AC   Q5JQS6; B2R4Y5; B3KX46; Q5JQT3;
DE   RecName: Full=Germinal center-associated signaling and motility-like protein;
GN   Name=GCSAML; Synonyms=C1orf150;
//
ID   GSC1L_HUMAN             Reviewed;        1079 AA.
AC   Q6AI39; A1L3W2; Q5TFZ3; Q92514;
DE   RecName: Full=GLTSCR1-like protein;
DE   AltName: Full=Glioma tumor suppressor candidate region gene 1 protein-like;
GN   Name=GLTSCR1L; Synonyms=KIAA0240;
//
ID   GSCR1_HUMAN             Reviewed;        1560 AA.
AC   Q9NZM4; A8MW01;
DE   RecName: Full=Glioma tumor suppressor candidate region gene 1 protein;
GN   Name=GLTSCR1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GSC2_HUMAN              Reviewed;         205 AA.
AC   O15499;
DE   RecName: Full=Homeobox protein goosecoid-2;
DE            Short=GSC-2;
DE   AltName: Full=Homeobox protein goosecoid-like;
DE            Short=GSC-L;
GN   Name=GSC2; Synonyms=GSCL;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
//
ID   GSCR2_HUMAN             Reviewed;         478 AA.
AC   Q9NZM5; Q9BTC6; Q9HAX6; Q9NPP1; Q9NPR4; Q9UFI2;
DE   RecName: Full=Glioma tumor suppressor candidate region gene 2 protein;
DE   AltName: Full=p60;
GN   Name=GLTSCR2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   GSC_HUMAN               Reviewed;         257 AA.
AC   P56915; Q86YR1;
DE   RecName: Full=Homeobox protein goosecoid;
GN   Name=GSC;
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007369; P:gastrulation; NAS:UniProtKB.
DR   GO; GO:0042474; P:middle ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
//
ID   GSDMA_HUMAN             Reviewed;         445 AA.
AC   Q96QA5; Q32MC5; Q86VE7; Q8N1M6;
DE   RecName: Full=Gasdermin-A;
DE   AltName: Full=Gasdermin-1;
GN   Name=GSDMA; Synonyms=GSDM, GSDM1; ORFNames=FKSG9;
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
//
ID   GSDMB_HUMAN             Reviewed;         411 AA.
AC   Q8TAX9; B4DKK7; Q7Z377; Q8WY76; Q9NX71; Q9P163;
DE   RecName: Full=Gasdermin-B;
DE   AltName: Full=Gasdermin-like protein;
GN   Name=GSDMB; Synonyms=GSDML; ORFNames=PP4052, PRO2521;
//
ID   GSDMC_HUMAN             Reviewed;         508 AA.
AC   Q9BYG8; Q5XKF3; Q6P494;
DE   RecName: Full=Gasdermin-C;
DE   AltName: Full=Melanoma-derived leucine zipper-containing extranuclear factor;
GN   Name=GSDMC; Synonyms=MLZE;
//
ID   GSE1_HUMAN              Reviewed;        1217 AA.
AC   Q14687; D3DUM4; Q8IY61; Q96GA4; Q9BW09;
DE   RecName: Full=Genetic suppressor element 1;
GN   Name=GSE1; Synonyms=KIAA0182;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GSDMD_HUMAN             Reviewed;         484 AA.
AC   P57764; D3DWJ9; Q96Q98;
DE   RecName: Full=Gasdermin-D;
DE   AltName: Full=Gasdermin domain-containing protein 1;
GN   Name=GSDMD; Synonyms=DFNA5L, GSDMDC1; ORFNames=FKSG10;
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
//
ID   GSG1L_HUMAN             Reviewed;         331 AA.
AC   Q6UXU4; Q7Z6F8; Q8TB81;
DE   RecName: Full=Germ cell-specific gene 1-like protein;
DE            Short=GSG1-like protein;
GN   Name=GSG1L; ORFNames=UNQ5831/PRO19651;
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; IEA:Ensembl.
//
ID   GSG1M_HUMAN             Reviewed;         235 AA.
AC   A8MUP6;
DE   RecName: Full=Putative germ cell-specific gene 1-like protein 2;
DE            Short=GSG1-like protein 2;
DE   Flags: Precursor;
//
ID   GSG1_HUMAN              Reviewed;         349 AA.
AC   Q2KHT4; Q8N4M3; Q8NBR4; Q8NBS0; Q8NBT1; Q96LP9; Q96SI6; Q9BUY4;
DE   RecName: Full=Germ cell-specific gene 1 protein;
GN   Name=GSG1; ORFNames=UNQ709/PRO1360;
//
ID   GSH0_HUMAN              Reviewed;         274 AA.
AC   P48507; A8K334; D3DT45; Q6FHC1; Q9NPX9; Q9NU74;
DE   RecName: Full=Glutamate--cysteine ligase regulatory subunit;
DE   AltName: Full=GCS light chain;
DE   AltName: Full=Gamma-ECS regulatory subunit;
DE   AltName: Full=Gamma-glutamylcysteine synthetase regulatory subunit;
DE   AltName: Full=Glutamate--cysteine ligase modifier subunit;
GN   Name=GCLM; Synonyms=GLCLR;
DR   GO; GO:0004357; F:glutamate-cysteine ligase activity; IEA:Ensembl.
DR   GO; GO:0035226; F:glutamate-cysteine ligase catalytic subunit binding; IPI:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006534; P:cysteine metabolic process; IEA:Ensembl.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0035229; P:positive regulation of glutamate-cysteine ligase activity; IEA:Ensembl.
DR   GO; GO:0050880; P:regulation of blood vessel size; IMP:UniProtKB.
DR   GO; GO:0051900; P:regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSH1_HUMAN              Reviewed;         637 AA.
AC   P48506; Q14399;
DE   RecName: Full=Glutamate--cysteine ligase catalytic subunit;
DE            EC=6.3.2.2;
DE   AltName: Full=GCS heavy chain;
DE   AltName: Full=Gamma-ECS;
DE   AltName: Full=Gamma-glutamylcysteine synthetase;
GN   Name=GCLC; Synonyms=GLCL, GLCLC;
DR   GO; GO:0043531; F:ADP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050662; F:coenzyme binding; IPI:UniProtKB.
DR   GO; GO:0016595; F:glutamate binding; IDA:UniProtKB.
DR   GO; GO:0004357; F:glutamate-cysteine ligase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006534; P:cysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006536; P:glutamate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0050880; P:regulation of blood vessel size; IMP:UniProtKB.
DR   GO; GO:0051900; P:regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
DR   GO; GO:0051409; P:response to nitrosative stress; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSHB_HUMAN              Reviewed;         474 AA.
AC   P48637; B2R697; B6F210; E1P5P9; Q4TTD9;
DE   RecName: Full=Glutathione synthetase;
DE            Short=GSH synthetase;
DE            Short=GSH-S;
DE            EC=6.3.2.3;
DE   AltName: Full=Glutathione synthase;
GN   Name=GSS;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0043295; F:glutathione binding; IDA:UniProtKB.
DR   GO; GO:0004363; F:glutathione synthase activity; TAS:Reactome.
DR   GO; GO:0016594; F:glycine binding; IEA:Ensembl.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006750; P:glutathione biosynthetic process; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSHR_HUMAN              Reviewed;         522 AA.
AC   P00390; C8KIL8; C8KIL9; C8KIM0; D3DSV3; Q7Z5C9; Q9NP63;
DE   RecName: Full=Glutathione reductase, mitochondrial;
DE            Short=GR;
DE            Short=GRase;
DE            EC=1.8.1.7;
DE   Flags: Precursor;
GN   Name=GSR; Synonyms=GLUR, GRD1;
DR   GuidetoPHARMACOLOGY; 2613; -.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004362; F:glutathione-disulfide reductase activity; TAS:Reactome.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GSK3A_HUMAN             Reviewed;         483 AA.
AC   P49840; O14959;
DE   RecName: Full=Glycogen synthase kinase-3 alpha;
DE            Short=GSK-3 alpha;
DE            EC=2.7.11.26;
DE   AltName: Full=Serine/threonine-protein kinase GSK3A;
DE            EC=2.7.11.1;
GN   Name=GSK3A;
DR   GuidetoPHARMACOLOGY; 2029; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0036016; P:cellular response to interleukin-3; ISS:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; ISS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:UniProtKB.
DR   GO; GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0046325; P:negative regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:BHF-UCL.
DR   GO; GO:0051348; P:negative regulation of transferase activity; IMP:BHF-UCL.
DR   GO; GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.
DR   GO; GO:0010905; P:negative regulation of UDP-glucose catabolic process; IC:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:BHF-UCL.
DR   GO; GO:0045823; P:positive regulation of heart contraction; ISS:BHF-UCL.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; NAS:BHF-UCL.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   GSK3B_HUMAN             Reviewed;         420 AA.
AC   P49841; D3DN89; Q9BWH3; Q9UL47;
DE   RecName: Full=Glycogen synthase kinase-3 beta;
DE            Short=GSK-3 beta;
DE            EC=2.7.11.26;
DE   AltName: Full=Serine/threonine-protein kinase GSK3B;
DE            EC=2.7.11.1;
GN   Name=GSK3B;
DR   GuidetoPHARMACOLOGY; 2030; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0016301; F:kinase activity; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IC:UniProtKB.
DR   GO; GO:0044337; P:canonical Wnt signaling pathway involved in positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0036016; P:cellular response to interleukin-3; ISS:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.
DR   GO; GO:0006983; P:ER overload response; IDA:MGI.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; IDA:BHF-UCL.
DR   GO; GO:0021766; P:hippocampus development; IMP:BHF-UCL.
DR   GO; GO:0044027; P:hypermethylation of CpG island; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; TAS:UniProtKB.
DR   GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:0050774; P:negative regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.
DR   GO; GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; ISS:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.
DR   GO; GO:2000738; P:positive regulation of stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0035372; P:protein localization to microtubule; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0000320; P:re-entry into mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0071109; P:superior temporal gyrus development; IMP:BHF-UCL.
//
ID   GSLG1_HUMAN             Reviewed;        1179 AA.
AC   Q92896; B7Z8Y4; D3DUJ7; Q13221; Q6P9D1;
DE   RecName: Full=Golgi apparatus protein 1;
DE   AltName: Full=CFR-1;
DE   AltName: Full=Cysteine-rich fibroblast growth factor receptor;
DE   AltName: Full=E-selectin ligand 1;
DE            Short=ESL-1;
DE   AltName: Full=Golgi sialoglycoprotein MG-160;
DE   Flags: Precursor;
GN   Name=GLG1; Synonyms=CFR1, ESL1, MG160;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0010955; P:negative regulation of protein processing; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; IEA:Ensembl.
//
ID   GSKIP_HUMAN             Reviewed;         139 AA.
AC   Q9P0R6; B3KSZ0; Q9BST1; Q9NWK0;
DE   RecName: Full=GSK3-beta interaction protein;
DE            Short=GSKIP;
GN   Name=GSKIP; Synonyms=C14orf129; ORFNames=HSPC210;
//
ID   GST2_HUMAN              Reviewed;         244 AA.
AC   P0CG29; O60665; P30712; Q6IPV7; Q9HD76;
DE   RecName: Full=Glutathione S-transferase theta-2;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-theta-2;
GN   Name=GSTT2;
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
//
ID   GSTA1_HUMAN             Reviewed;         222 AA.
AC   P08263; Q14750; Q5GHF8; Q5SZC1;
DE   RecName: Full=Glutathione S-transferase A1;
DE            EC=2.5.1.18;
DE   AltName: Full=GST HA subunit 1;
DE   AltName: Full=GST class-alpha member 1;
DE   AltName: Full=GST-epsilon;
DE   AltName: Full=GSTA1-1;
DE   AltName: Full=GTH1;
DE   Contains:
DE     RecName: Full=Glutathione S-transferase A1, N-terminally processed;
GN   Name=GSTA1;
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IC:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTA2_HUMAN             Reviewed;         222 AA.
AC   P09210; Q12759; Q16491; Q9NTY6;
DE   RecName: Full=Glutathione S-transferase A2;
DE            EC=2.5.1.18;
DE   AltName: Full=GST HA subunit 2;
DE   AltName: Full=GST class-alpha member 2;
DE   AltName: Full=GST-gamma;
DE   AltName: Full=GSTA2-2;
DE   AltName: Full=GTH2;
GN   Name=GSTA2; Synonyms=GST2;
DR   GO; GO:0004364; F:glutathione transferase activity; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTA3_HUMAN             Reviewed;         222 AA.
AC   Q16772; O43468; Q068V6; Q8WWA8; Q9H415;
DE   RecName: Full=Glutathione S-transferase A3;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-alpha member 3;
DE   AltName: Full=Glutathione S-transferase A3-3;
GN   Name=GSTA3;
DR   GO; GO:0004364; F:glutathione transferase activity; ISS:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTA4_HUMAN             Reviewed;         222 AA.
AC   O15217; B2RD15; Q5T7Q8; Q9BX18; Q9H414;
DE   RecName: Full=Glutathione S-transferase A4;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-alpha member 4;
DE   AltName: Full=Glutathione S-transferase A4-4;
GN   Name=GSTA4;
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   GSTA5_HUMAN             Reviewed;         222 AA.
AC   Q7RTV2; Q5SZC2;
DE   RecName: Full=Glutathione S-transferase A5;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-alpha member 5;
DE   AltName: Full=Glutathione S-transferase A5-5;
GN   Name=GSTA5;
DR   GO; GO:0004364; F:glutathione transferase activity; ISS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.
//
ID   GSTCD_HUMAN             Reviewed;         633 AA.
AC   Q8NEC7; A8K8J0; A8MVD3; H9KV97; Q9H8S3;
DE   RecName: Full=Glutathione S-transferase C-terminal domain-containing protein;
GN   Name=GSTCD;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GSTK1_HUMAN             Reviewed;         226 AA.
AC   Q9Y2Q3; B4DIH1; B4DSY2; Q6P4H0; Q7Z520; Q9P1S4;
DE   RecName: Full=Glutathione S-transferase kappa 1;
DE            EC=2.5.1.18;
DE   AltName: Full=GST 13-13;
DE   AltName: Full=GST class-kappa;
DE   AltName: Full=GSTK1-1;
DE            Short=hGSTK1;
DE   AltName: Full=Glutathione S-transferase subunit 13;
GN   Name=GSTK1; ORFNames=HDCMD47P;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
//
ID   GSTM1_HUMAN             Reviewed;         218 AA.
AC   P09488; Q5GHG0; Q6FH88; Q8TC98; Q9UC96;
DE   RecName: Full=Glutathione S-transferase Mu 1;
DE            EC=2.5.1.18;
DE   AltName: Full=GST HB subunit 4;
DE   AltName: Full=GST class-mu 1;
DE   AltName: Full=GSTM1-1;
DE   AltName: Full=GSTM1a-1a;
DE   AltName: Full=GSTM1b-1b;
DE   AltName: Full=GTH4;
GN   Name=GSTM1; Synonyms=GST1;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0043295; F:glutathione binding; IDA:BHF-UCL.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0070458; P:cellular detoxification of nitrogen compound; IDA:BHF-UCL.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:BHF-UCL.
DR   GO; GO:0018916; P:nitrobenzene metabolic process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTM2_HUMAN             Reviewed;         218 AA.
AC   P28161; B4DRY4; E9PEM9; Q2M318; Q5TZY5; Q8WWE1;
DE   RecName: Full=Glutathione S-transferase Mu 2;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-mu 2;
DE   AltName: Full=GSTM2-2;
GN   Name=GSTM2; Synonyms=GST4;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0043295; F:glutathione binding; IDA:BHF-UCL.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0070458; P:cellular detoxification of nitrogen compound; IDA:BHF-UCL.
DR   GO; GO:0071313; P:cellular response to caffeine; IDA:BHF-UCL.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0018916; P:nitrobenzene metabolic process; IDA:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IC:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL.
DR   GO; GO:0014809; P:regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; IC:BHF-UCL.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; TAS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTM3_HUMAN             Reviewed;         225 AA.
AC   P21266; O60550; Q96HA3;
DE   RecName: Full=Glutathione S-transferase Mu 3;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-mu 3;
DE   AltName: Full=GSTM3-3;
DE            Short=hGSTM3-3;
GN   Name=GSTM3; Synonyms=GST5;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0043295; F:glutathione binding; IDA:BHF-UCL.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0070458; P:cellular detoxification of nitrogen compound; IDA:BHF-UCL.
DR   GO; GO:0008065; P:establishment of blood-nerve barrier; TAS:ProtInc.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0018916; P:nitrobenzene metabolic process; IDA:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTM4_HUMAN             Reviewed;         218 AA.
AC   Q03013; A8K765; Q05465; Q32NC1; Q4JNT8; Q6FH87;
DE   RecName: Full=Glutathione S-transferase Mu 4;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-mu 4;
DE   AltName: Full=GST-Mu2;
DE   AltName: Full=GSTM4-4;
GN   Name=GSTM4;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0043295; F:glutathione binding; IDA:BHF-UCL.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTM5_HUMAN             Reviewed;         218 AA.
AC   P46439; A8K0V8; Q6PD78;
DE   RecName: Full=Glutathione S-transferase Mu 5;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-mu 5;
DE   AltName: Full=GSTM5-5;
GN   Name=GSTM5;
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTO1_HUMAN             Reviewed;         241 AA.
AC   P78417; D3DRA3; F5H7H0; Q5TA03; Q7Z3T2;
DE   RecName: Full=Glutathione S-transferase omega-1;
DE            Short=GSTO-1;
DE            EC=2.5.1.18;
DE   AltName: Full=Glutathione S-transferase omega 1-1;
DE            Short=GSTO 1-1;
DE   AltName: Full=Glutathione-dependent dehydroascorbate reductase;
DE            EC=1.8.5.1;
DE   AltName: Full=Monomethylarsonic acid reductase;
DE            Short=MMA(V) reductase;
DE            EC=1.20.4.2;
DE   AltName: Full=S-(Phenacyl)glutathione reductase;
DE            Short=SPG-R;
GN   Name=GSTO1; Synonyms=GSTTLP28;
DR   GO; GO:0045174; F:glutathione dehydrogenase (ascorbate) activity; IDA:UniProtKB.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0050610; F:methylarsonate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0014810; P:positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; IC:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IC:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTO2_HUMAN             Reviewed;         243 AA.
AC   Q9H4Y5; A8K771; B4DJW6; E7ESD6; Q49TW5; Q5GM70; Q5JU15; Q86WP3;
DE   RecName: Full=Glutathione S-transferase omega-2;
DE            Short=GSTO-2;
DE            EC=2.5.1.18;
DE   AltName: Full=Glutathione S-transferase omega 2-2;
DE            Short=GSTO 2-2;
DE   AltName: Full=Glutathione-dependent dehydroascorbate reductase;
DE            EC=1.8.5.1;
DE   AltName: Full=Monomethylarsonic acid reductase;
DE            Short=MMA(V) reductase;
DE            EC=1.20.4.2;
GN   Name=GSTO2;
DR   GO; GO:0045174; F:glutathione dehydrogenase (ascorbate) activity; IDA:UniProtKB.
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050610; F:methylarsonate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   GSTP1_HUMAN             Reviewed;         210 AA.
AC   P09211; O00460; Q15690; Q5TZY3;
DE   RecName: Full=Glutathione S-transferase P;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-pi;
DE   AltName: Full=GSTP1-1;
GN   Name=GSTP1; Synonyms=FAEES3, GST3;
DR   GO; GO:0035731; F:dinitrosyl-iron complex binding; IDA:BHF-UCL.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0008432; F:JUN kinase binding; ISS:BHF-UCL.
DR   GO; GO:0019207; F:kinase regulator activity; ISS:BHF-UCL.
DR   GO; GO:0070026; F:nitric oxide binding; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035730; F:S-nitrosoglutathione binding; IDA:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0035726; P:common myeloid progenitor cell proliferation; ISS:BHF-UCL.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; NAS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0009890; P:negative regulation of biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; ISS:BHF-UCL.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IDA:BHF-UCL.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0070664; P:negative regulation of leukocyte proliferation; ISS:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; NAS:BHF-UCL.
DR   GO; GO:0071638; P:negative regulation of monocyte chemotactic protein-1 production; IDA:BHF-UCL.
DR   GO; GO:0051771; P:negative regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0035732; P:nitric oxide storage; NAS:BHF-UCL.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; ISS:BHF-UCL.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0000302; P:response to reactive oxygen species; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   GSTT1_HUMAN             Reviewed;         240 AA.
AC   P30711; O00226; Q5TZY2; Q969K8; Q96IY3;
DE   RecName: Full=Glutathione S-transferase theta-1;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-theta-1;
DE   AltName: Full=Glutathione transferase T1-1;
GN   Name=GSTT1;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSTT2_HUMAN             Reviewed;         244 AA.
AC   P0CG30; O60665; P30712; Q6IPV7; Q9HD76;
DE   RecName: Full=Glutathione S-transferase theta-2B;
DE            EC=2.5.1.18;
DE   AltName: Full=GST class-theta-2;
DE   AltName: Full=Glutathione S-transferase theta-2;
GN   Name=GSTT2B; Synonyms=GSTT2;
DR   GO; GO:0004364; F:glutathione transferase activity; NAS:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   GSX1_HUMAN              Reviewed;         264 AA.
AC   Q9H4S2; Q9UD62;
DE   RecName: Full=GS homeobox 1;
DE   AltName: Full=Homeobox protein GSH-1;
GN   Name=GSX1; Synonyms=GSH1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0021984; P:adenohypophysis development; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GSX2_HUMAN              Reviewed;         304 AA.
AC   Q9BZM3;
DE   RecName: Full=GS homeobox 2;
DE   AltName: Full=Homeobox protein GSH-2;
GN   Name=GSX2; Synonyms=GSH2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0021798; P:forebrain dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021575; P:hindbrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0021889; P:olfactory bulb interneuron differentiation; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0060163; P:subpallium neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GT251_HUMAN             Reviewed;         622 AA.
AC   Q8NBJ5; Q8NC64;
DE   RecName: Full=Procollagen galactosyltransferase 1;
DE            EC=2.4.1.50;
DE   AltName: Full=Collagen beta(1-O)galactosyltransferase 1;
DE   AltName: Full=Glycosyltransferase 25 family member 1;
DE   AltName: Full=Hydroxylysine galactosyltransferase 1;
DE   Flags: Precursor;
GN   Name=COLGALT1; Synonyms=GLT25D1; ORFNames=PSEC0241;
DR   GO; GO:0050211; F:procollagen galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
//
ID   GT252_HUMAN             Reviewed;         626 AA.
AC   Q8IYK4; O60327; Q9BZR0;
DE   RecName: Full=Procollagen galactosyltransferase 2;
DE            EC=2.4.1.50;
DE   AltName: Full=Collagen beta(1-O)galactosyltransferase 2;
DE   AltName: Full=Glycosyltransferase 25 family member 2;
DE   AltName: Full=Hydroxylysine galactosyltransferase 2;
DE   Flags: Precursor;
GN   Name=COLGALT2; Synonyms=C1orf17, GLT25D2, KIAA0584;
DR   GO; GO:0050211; F:procollagen galactosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
//
ID   GT2D1_HUMAN             Reviewed;         959 AA.
AC   Q9UHL9; O95444; Q6DSU6; Q75MX7; Q86UM3; Q8WVC4; Q9UHK8; Q9UI91;
DE   RecName: Full=General transcription factor II-I repeat domain-containing protein 1;
DE            Short=GTF2I repeat domain-containing protein 1;
DE   AltName: Full=General transcription factor III;
DE   AltName: Full=MusTRD1/BEN;
DE   AltName: Full=Muscle TFII-I repeat domain-containing protein 1;
DE   AltName: Full=Slow-muscle-fiber enhancer-binding protein;
DE   AltName: Full=USE B1-binding protein;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 11 protein;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 12 protein;
GN   Name=GTF2IRD1;
GN   Synonyms=CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; NAS:GOC.
//
ID   GT253_HUMAN             Reviewed;         595 AA.
AC   Q5T4B2; A7MD00; C4AMA2; Q0VDF3; Q2VPJ4; Q4KMP2; Q5T4B1; Q8N107;
AC   Q96EZ5; Q9P226; Q9UMW5;
DE   RecName: Full=Probable inactive glycosyltransferase 25 family member 3;
DE   AltName: Full=Cerebral endothelial cell adhesion molecule;
DE   Flags: Precursor;
GN   Name=CERCAM; Synonyms=CEECAM1, GLT25D3, KIAA1502;
DR   GO; GO:0007155; P:cell adhesion; IDA:MGI.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; TAS:ProtInc.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
//
ID   GTD2A_HUMAN             Reviewed;         949 AA.
AC   Q86UP8; A8K5W6; B3KUZ2; Q69G40; Q6EKI8; Q6EKI9; Q6NVW2; Q6P7N8;
AC   Q86WX4; Q8ND85; Q8NDE5;
DE   RecName: Full=General transcription factor II-I repeat domain-containing protein 2A;
DE            Short=GTF2I repeat domain-containing protein 2A;
DE   AltName: Full=Transcription factor GTF2IRD2-alpha;
GN   Name=GTF2IRD2; Synonyms=GTF2IRD2A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GTD2B_HUMAN             Reviewed;         949 AA.
AC   Q6EKJ0; B2RNE9; Q69GU6; Q8N979; Q9H739;
DE   RecName: Full=General transcription factor II-I repeat domain-containing protein 2B;
DE            Short=GTF2I repeat domain-containing protein 2B;
DE   AltName: Full=Transcription factor GTF2IRD2-beta;
GN   Name=GTF2IRD2B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   GTDC1_HUMAN             Reviewed;         458 AA.
AC   Q4AE62; A8K5P2; D3DP81; Q53SM7; Q53TC5; Q6P7E7; Q6PJB6; Q6WKW6;
AC   Q9HAE5;
DE   RecName: Full=Glycosyltransferase-like domain-containing protein 1;
DE   AltName: Full=Mat-Xa;
GN   Name=GTDC1;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
//
ID   GTF2I_HUMAN             Reviewed;         998 AA.
AC   P78347; O14743; O15359; O43546; O43588; O43589; Q75M85; Q75M86;
AC   Q75M87; Q75M88; Q9BSZ4;
DE   RecName: Full=General transcription factor II-I;
DE            Short=GTFII-I;
DE            Short=TFII-I;
DE   AltName: Full=Bruton tyrosine kinase-associated protein 135;
DE            Short=BAP-135;
DE            Short=BTK-associated protein 135;
DE   AltName: Full=SRF-Phox1-interacting protein;
DE            Short=SPIN;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 6 protein;
GN   Name=GTF2I; Synonyms=BAP135, WBSCR6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:MGI.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:ProtInc.
//
ID   GTL3B_HUMAN             Reviewed;         113 AA.
AC   Q8N6N6; A8MWQ7; B3KX70;
DE   RecName: Full=Protein GTLF3B;
GN   Name=GTLF3B; Synonyms=C17orf103;
//
ID   GTPB1_HUMAN             Reviewed;         669 AA.
AC   O00178; Q6IC67;
DE   RecName: Full=GTP-binding protein 1;
DE            Short=G-protein 1;
DE            Short=GP-1;
DE            Short=GP1;
GN   Name=GTPBP1;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0061014; P:positive regulation of mRNA catabolic process; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   GTPB2_HUMAN             Reviewed;         602 AA.
AC   Q9BX10; Q5T7E8; Q8ND84; Q8TAH7; Q8WUA5; Q9HCS9; Q9NRU4; Q9NX60;
DE   RecName: Full=GTP-binding protein 2;
GN   Name=GTPBP2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   GTPB3_HUMAN             Reviewed;         492 AA.
AC   Q969Y2; A6NFH1; A6NIG5; A6NKR4; A8K7B4; B7Z4V8; Q8TCY6; Q8WUW9;
AC   Q969G4; Q9BX61;
DE   RecName: Full=tRNA modification GTPase GTPBP3, mitochondrial;
DE   AltName: Full=GTP-binding protein 3;
DE   AltName: Full=Mitochondrial GTP-binding protein 1;
DE   Flags: Precursor;
GN   Name=GTPBP3; Synonyms=MTGP1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006400; P:tRNA modification; IEA:InterPro.
//
ID   GTPB6_HUMAN             Reviewed;         516 AA.
AC   O43824; Q53F77; Q5HYX8;
DE   RecName: Full=Putative GTP-binding protein 6;
DE   AltName: Full=Pseudoautosomal GTP-binding protein-like;
GN   Name=GTPBP6; Synonyms=PGPL;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
//
ID   GTPB8_HUMAN             Reviewed;         284 AA.
AC   Q8N3Z3; A6NE99; A6NN11; A8K0P6; Q5I0Y4;
DE   RecName: Full=GTP-binding protein 8;
GN   Name=GTPBP8;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000917; P:barrier septum assembly; IEA:InterPro.
//
ID   GTPBA_HUMAN             Reviewed;         387 AA.
AC   A4D1E9; B4DFY6; Q3B7A6; Q5H9V2; Q8IXG8; Q8N982; Q8WU16; Q9BSP1;
AC   Q9Y6T6;
DE   RecName: Full=GTP-binding protein 10;
DE   AltName: Full=Protein obg homolog 2;
DE            Short=ObgH2;
GN   Name=GTPBP10; Synonyms=OBGH2; ORFNames=UG0751c10;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   GTPC1_HUMAN             Reviewed;         377 AA.
AC   Q9GZT8; Q53TX4; Q6X735; Q9H2D2; Q9HC18;
DE   RecName: Full=Putative GTP cyclohydrolase 1 type 2 NIF3L1;
DE            EC=3.5.4.16;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein;
DE   AltName: Full=GTP cyclohydrolase I;
DE   AltName: Full=NIF3-like protein 1;
GN   Name=NIF3L1; Synonyms=ALS2CR1; ORFNames=MDS015, My018;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003934; F:GTP cyclohydrolase I activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0035998; P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
//
ID   GTR10_HUMAN             Reviewed;         541 AA.
AC   O95528; A8K4J6; Q3MIX5; Q9H4I6;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 10;
DE   AltName: Full=Glucose transporter type 10;
DE            Short=GLUT-10;
GN   Name=SLC2A10; Synonyms=GLUT10;
DR   GO; GO:0005351; F:sugar:proton symporter activity; NAS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; NAS:UniProtKB.
DR   GO; GO:0015992; P:proton transport; NAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR11_HUMAN             Reviewed;         496 AA.
AC   Q9BYW1; E9PH55; Q542Y4; Q6ICJ5; Q8WXF9; Q8WYM4;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 11;
DE   AltName: Full=Glucose transporter type 10;
DE            Short=GLUT-10;
DE   AltName: Full=Glucose transporter type 11;
DE            Short=GLUT-11;
GN   Name=SLC2A11; Synonyms=GLUT10, GLUT11;
DR   GO; GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR12_HUMAN             Reviewed;         617 AA.
AC   Q8TD20; B3KV17; Q7Z6U3; Q96MR8;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 12;
DE   AltName: Full=Glucose transporter type 12;
DE            Short=GLUT-12;
GN   Name=SLC2A12; Synonyms=GLUT12, GLUT8;
DR   GO; GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR14_HUMAN             Reviewed;         520 AA.
AC   Q8TDB8; B3KVB5; B3KWW7; Q6UY84; Q8TDB9;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 14;
DE   AltName: Full=Glucose transporter type 14;
DE            Short=GLUT-14;
GN   Name=SLC2A14; Synonyms=GLUT14, GLUT3;
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   GTR1_HUMAN              Reviewed;         492 AA.
AC   P11166; A8K9S6; B2R620; D3DPX0; O75535; Q147X2;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 1;
DE   AltName: Full=Glucose transporter type 1, erythrocyte/brain;
DE            Short=GLUT-1;
DE   AltName: Full=HepG2 glucose transporter;
GN   Name=SLC2A1; Synonyms=GLUT1;
DR   GuidetoPHARMACOLOGY; 875; -.
DR   GO; GO:0055056; F:D-glucose transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0033300; F:dehydroascorbic acid transporter activity; IEA:Ensembl.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0042910; F:xenobiotic transporter activity; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   GTR2_HUMAN              Reviewed;         524 AA.
AC   P11168; A8K481; B2R936; B7Z547; F8W8V8; Q9UCW9;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 2;
DE   AltName: Full=Glucose transporter type 2, liver;
DE            Short=GLUT-2;
GN   Name=SLC2A2; Synonyms=GLUT2;
DR   GuidetoPHARMACOLOGY; 876; -.
DR   GO; GO:0055056; F:D-glucose transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0033300; F:dehydroascorbic acid transporter activity; IEA:Ensembl.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; EXP:Reactome.
DR   GO; GO:0015149; F:hexose transmembrane transporter activity; TAS:Reactome.
DR   GO; GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0035428; P:hexose transmembrane transport; TAS:GOC.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR3_HUMAN              Reviewed;         496 AA.
AC   P11169; B2R606; D3DUU6; Q6I9U2; Q9UG15;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 3;
DE   AltName: Full=Glucose transporter type 3, brain;
DE            Short=GLUT-3;
GN   Name=SLC2A3; Synonyms=GLUT3;
DR   GuidetoPHARMACOLOGY; 877; -.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   GTR4_HUMAN              Reviewed;         509 AA.
AC   P14672; Q14CX2;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 4;
DE   AltName: Full=Glucose transporter type 4, insulin-responsive;
DE            Short=GLUT-4;
GN   Name=SLC2A4; Synonyms=GLUT4;
DR   GuidetoPHARMACOLOGY; 878; -.
DR   GO; GO:0055056; F:D-glucose transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010021; P:amylopectin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IDA:BHF-UCL.
DR   GO; GO:0046323; P:glucose import; NAS:BHF-UCL.
DR   GO; GO:0015758; P:glucose transport; TAS:UniProtKB.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR5_HUMAN              Reviewed;         501 AA.
AC   P22732; Q14770; Q5T977; Q8IVB3;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 5;
DE   AltName: Full=Fructose transporter;
DE   AltName: Full=Glucose transporter type 5, small intestine;
DE            Short=GLUT-5;
GN   Name=SLC2A5; Synonyms=GLUT5;
DR   GO; GO:0005353; F:fructose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071332; P:cellular response to fructose stimulus; ISS:UniProtKB.
DR   GO; GO:0015755; P:fructose transport; TAS:ProtInc.
DR   GO; GO:0015758; P:glucose transport; TAS:ProtInc.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR6_HUMAN              Reviewed;         507 AA.
AC   Q9UGQ3; A6NNU6; Q5SXD7; Q8NCC2;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 6;
DE   AltName: Full=Glucose transporter type 6;
DE            Short=GLUT-6;
DE   AltName: Full=Glucose transporter type 9;
DE            Short=GLUT-9;
GN   Name=SLC2A6; Synonyms=GLUT9;
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; NAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR7_HUMAN              Reviewed;         512 AA.
AC   Q6PXP3; A2A333;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 7;
DE   AltName: Full=Glucose transporter type 7;
DE            Short=GLUT-7;
GN   Name=SLC2A7; Synonyms=GLUT7;
DR   GO; GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR8_HUMAN              Reviewed;         477 AA.
AC   Q9NY64; Q8WUZ9; Q9NSC4;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 8;
DE   AltName: Full=Glucose transporter type 8;
DE            Short=GLUT-8;
DE   AltName: Full=Glucose transporter type X1;
GN   Name=SLC2A8; Synonyms=GLUT8, GLUTX1;
DR   GO; GO:0005536; F:glucose binding; IEA:Ensembl.
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0015758; P:glucose transport; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   GTR9_HUMAN              Reviewed;         540 AA.
AC   Q9NRM0; Q0VGC4; Q4W5D1; Q8WV30; Q96P00;
DE   RecName: Full=Solute carrier family 2, facilitated glucose transporter member 9;
DE   AltName: Full=Glucose transporter type 9;
DE            Short=GLUT-9;
GN   Name=SLC2A9; Synonyms=GLUT9;
DR   GO; GO:0005355; F:glucose transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005351; F:sugar:proton symporter activity; NAS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; NAS:UniProtKB.
DR   GO; GO:0015992; P:proton transport; NAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046415; P:urate metabolic process; IMP:UniProtKB.
//
ID   GTSF1_HUMAN             Reviewed;         167 AA.
AC   Q8WW33; B3KQ60; Q0VGM4; Q8N778;
DE   RecName: Full=Gametocyte-specific factor 1;
DE   AltName: Full=Protein FAM112B;
GN   Name=GTSF1; Synonyms=FAM112B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   GTSC1_HUMAN             Reviewed;         136 AA.
AC   Q86UQ5;
DE   RecName: Full=Gilles de la Tourette syndrome chromosomal region candidate gene 1 protein;
GN   Name=GTSCR1;
//
ID   GTSE1_HUMAN             Reviewed;         720 AA.
AC   Q9NYZ3; B0QYM3; Q20WK2; Q53GX5; Q5R3I6; Q6DHX4; Q9BRE0; Q9UGZ9;
AC   Q9Y557;
DE   RecName: Full=G2 and S phase-expressed protein 1;
DE            Short=GTSE-1;
DE   AltName: Full=Protein B99 homolog;
GN   Name=GTSE1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; NAS:UniProtKB.
DR   GO; GO:0007017; P:microtubule-based process; NAS:UniProtKB.
DR   GO; GO:0000085; P:mitotic G2 phase; NAS:UniProtKB.
//
ID   GTSFL_HUMAN             Reviewed;         148 AA.
AC   Q9H1H1; Q5JWH5;
DE   RecName: Full=Gametocyte-specific factor 1-like;
DE   AltName: Full=Protein FAM112A;
GN   Name=GTSF1L; Synonyms=C20orf65, FAM112A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   GUAA_HUMAN              Reviewed;         693 AA.
AC   P49915; A8K639; B4DXV7; F8W720;
DE   RecName: Full=GMP synthase [glutamine-hydrolyzing];
DE            EC=6.3.5.2;
DE   AltName: Full=GMP synthetase;
DE   AltName: Full=Glutamine amidotransferase;
GN   Name=GMPS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0003921; F:GMP synthase activity; TAS:ProtInc.
DR   GO; GO:0016462; F:pyrophosphatase activity; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GUAD_HUMAN              Reviewed;         454 AA.
AC   Q9Y2T3; B4DTY5; Q5SZC7; Q9H335; Q9ULG2;
DE   RecName: Full=Guanine deaminase;
DE            Short=Guanase;
DE            Short=Guanine aminase;
DE            EC=3.5.4.3;
DE   AltName: Full=Guanine aminohydrolase;
DE            Short=GAH;
DE   AltName: Full=p51-nedasin;
GN   Name=GDA; Synonyms=KIAA1258;
DR   GO; GO:0008892; F:guanine deaminase activity; EXP:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006147; P:guanine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GUC1A_HUMAN             Reviewed;         201 AA.
AC   P43080; B3KWT4; Q7Z6T1; Q9NU14;
DE   RecName: Full=Guanylyl cyclase-activating protein 1;
DE            Short=GCAP 1;
DE   AltName: Full=Guanylate cyclase activator 1A;
GN   Name=GUCA1A; Synonyms=C6orf131, GCAP, GCAP1, GUCA1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008048; F:calcium sensitive guanylate cyclase activator activity; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   GUC1B_HUMAN             Reviewed;         200 AA.
AC   Q9UMX6; Q9NU15;
DE   RecName: Full=Guanylyl cyclase-activating protein 2;
DE            Short=GCAP 2;
DE   AltName: Full=Guanylate cyclase activator 1B;
GN   Name=GUCA1B; Synonyms=GCAP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008048; F:calcium sensitive guanylate cyclase activator activity; TAS:ProtInc.
DR   GO; GO:0007589; P:body fluid secretion; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; TAS:GOC.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   GUC1C_HUMAN             Reviewed;         209 AA.
AC   O95843; O95844; Q9UNM0;
DE   RecName: Full=Guanylyl cyclase-activating protein 3;
DE            Short=GCAP 3;
DE   AltName: Full=Guanylate cyclase activator 1C;
GN   Name=GUCA1C; Synonyms=GCAP3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008048; F:calcium sensitive guanylate cyclase activator activity; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; TAS:GOC.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   GUC2A_HUMAN             Reviewed;         115 AA.
AC   Q02747;
DE   RecName: Full=Guanylin;
DE   AltName: Full=Guanylate cyclase activator 2A;
DE   AltName: Full=Guanylate cyclase-activating protein 1;
DE   AltName: Full=Guanylate cyclase-activating protein I;
DE            Short=GCAP-I;
DE   Contains:
DE     RecName: Full=HMW-guanylin;
DE   Contains:
DE     RecName: Full=Guanylin;
DE   Flags: Precursor;
GN   Name=GUCA2A; Synonyms=GUCA2;
DR   GO; GO:0030250; F:guanylate cyclase activator activity; NAS:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; NAS:UniProtKB.
//
ID   GUC2B_HUMAN             Reviewed;         112 AA.
AC   Q16661; Q52LV0;
DE   RecName: Full=Guanylate cyclase activator 2B;
DE   Contains:
DE     RecName: Full=Guanylate cyclase C-activating peptide 2;
DE     AltName: Full=Guanylate cyclase C-activating peptide II;
DE              Short=GCAP-II;
DE   Contains:
DE     RecName: Full=Uroguanylin;
DE              Short=UGN;
DE   Flags: Precursor;
GN   Name=GUCA2B;
DR   GO; GO:0008048; F:calcium sensitive guanylate cyclase activator activity; TAS:ProtInc.
DR   GO; GO:0007589; P:body fluid secretion; IEA:Ensembl.
DR   GO; GO:0006182; P:cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; TAS:GOC.
//
ID   GUC2C_HUMAN             Reviewed;        1073 AA.
AC   P25092; B2RMY6;
DE   RecName: Full=Heat-stable enterotoxin receptor;
DE            Short=STA receptor;
DE            Short=hSTAR;
DE            EC=4.6.1.2;
DE   AltName: Full=Guanylyl cyclase C;
DE            Short=GC-C;
DE   AltName: Full=Intestinal guanylate cyclase;
DE   Flags: Precursor;
GN   Name=GUCY2C; Synonyms=GUC2C, STAR;
DR   GuidetoPHARMACOLOGY; 1750; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0015643; F:toxic substance binding; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; TAS:ProtInc.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
//
ID   GUC2D_HUMAN             Reviewed;        1103 AA.
AC   Q02846; Q6LEA7;
DE   RecName: Full=Retinal guanylyl cyclase 1;
DE            Short=RETGC-1;
DE            EC=4.6.1.2;
DE   AltName: Full=Guanylate cyclase 2D, retinal;
DE   AltName: Full=Rod outer segment membrane guanylate cyclase;
DE            Short=ROS-GC;
DE   Flags: Precursor;
GN   Name=GUCY2D; Synonyms=CORD6, GUC1A4, GUC2D, RETGC, RETGC1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   GUC2F_HUMAN             Reviewed;        1108 AA.
AC   P51841; Q9UJF1;
DE   RecName: Full=Retinal guanylyl cyclase 2;
DE            Short=RETGC-2;
DE            EC=4.6.1.2;
DE   AltName: Full=Guanylate cyclase 2F, retinal;
DE   AltName: Full=Guanylate cyclase F;
DE            Short=GC-F;
DE   AltName: Full=Rod outer segment membrane guanylate cyclase 2;
DE            Short=ROS-GC2;
DE   Flags: Precursor;
GN   Name=GUCY2F; Synonyms=GUC2F, RETGC2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   GUCD1_HUMAN             Reviewed;         240 AA.
AC   Q96NT3; B5MCB8; Q96Q79; Q9BU32;
DE   RecName: Full=Protein GUCD1;
DE   AltName: Full=Guanylyl cyclase domain-containing protein 1;
DE   AltName: Full=Protein LLN4;
GN   Name=GUCD1; Synonyms=C22orf13, LLN4;
//
ID   GUF1_HUMAN              Reviewed;         669 AA.
AC   Q8N442; Q5XKM8; Q9H710; Q9H8U4;
DE   RecName: Full=Translation factor GUF1, mitochondrial;
DE            EC=3.6.5.-;
DE   AltName: Full=Elongation factor 4 homolog;
DE            Short=EF-4;
DE   AltName: Full=GTPase GUF1;
DE   AltName: Full=Ribosomal back-translocase;
DE   Flags: Precursor;
GN   Name=GUF1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043022; F:ribosome binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
//
ID   GULP1_HUMAN             Reviewed;         304 AA.
AC   Q9UBP9; B2RB51; B4DQ40; B8ZZ72; D3DPH1; E9PB86; Q53PC1; Q53RF3;
AC   Q9BVL3;
DE   RecName: Full=PTB domain-containing engulfment adapter protein 1;
DE   AltName: Full=Cell death protein 6 homolog;
DE   AltName: Full=PTB domain adapter protein CED-6;
DE   AltName: Full=Protein GULP;
GN   Name=GULP1; Synonyms=CED6, GULP;
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   GUSP1_HUMAN             Reviewed;         140 AA.
AC   Q15486; A6NLY8; A8K1B7; Q969T8; Q9BUH2;
DE   RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;
GN   Name=GUSBP1; Synonyms=SMA3;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   GVIN1_HUMAN             Reviewed;        2422 AA.
AC   Q7Z2Y8; A6NFL2; Q9H8N5;
DE   RecName: Full=Interferon-induced very large GTPase 1;
DE   AltName: Full=Interferon-induced very large GTPase pseudogene 1;
GN   Name=GVINP1; Synonyms=GVIN1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
//
ID   GVQW1_HUMAN             Reviewed;         195 AA.
AC   Q8N7I0;
DE   RecName: Full=Protein GVQW1;
DE   AltName: Full=GVQW motif-containing protein 1;
DE   AltName: Full=Tigger transposable element-derived 1-like protein 2;
DE   Flags: Precursor;
GN   Name=GVQW1; Synonyms=TIGD1L2;
//
ID   GWL_HUMAN               Reviewed;         879 AA.
AC   Q96GX5; Q5T8D5; Q5T8D7; Q8NCD6; Q96SJ5;
DE   RecName: Full=Serine/threonine-protein kinase greatwall;
DE            Short=GW;
DE            Short=GWL;
DE            Short=hGWL;
DE            EC=2.7.11.1;
DE   AltName: Full=Microtubule-associated serine/threonine-protein kinase-like;
DE            Short=MAST-L;
GN   Name=MASTL; Synonyms=GW, GWL, THC2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IDA:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034048; P:negative regulation of protein phosphatase type 2A activity; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
//
ID   GXLT1_HUMAN             Reviewed;         440 AA.
AC   Q4G148; B3KWJ2; Q8IXV1; Q96BH4;
DE   RecName: Full=Glucoside xylosyltransferase 1;
DE            EC=2.4.2.n2;
DE   AltName: Full=Glycosyltransferase 8 domain-containing protein 3;
GN   Name=GXYLT1; Synonyms=GLT8D3;
DR   GO; GO:0035252; F:UDP-xylosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GXLT2_HUMAN             Reviewed;         443 AA.
AC   A0PJZ3;
DE   RecName: Full=Glucoside xylosyltransferase 2;
DE            EC=2.4.2.n2;
DE   AltName: Full=Glycosyltransferase 8 domain-containing protein 4;
GN   Name=GXYLT2; Synonyms=GLT8D4;
DR   GO; GO:0035252; F:UDP-xylosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; IDA:UniProtKB.
//
ID   GYS1_HUMAN              Reviewed;         737 AA.
AC   P13807; Q9BTT9;
DE   RecName: Full=Glycogen [starch] synthase, muscle;
DE            EC=2.4.1.11;
GN   Name=GYS1; Synonyms=GYS;
DR   GO; GO:0005536; F:glucose binding; IEA:Ensembl.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IDA:UniProtKB.
DR   GO; GO:0061547; F:glycogen synthase activity, transferring glucose-1-phosphate; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GYS2_HUMAN              Reviewed;         703 AA.
AC   P54840; A0AVD8;
DE   RecName: Full=Glycogen [starch] synthase, liver;
DE            EC=2.4.1.11;
GN   Name=GYS2;
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IDA:UniProtKB.
DR   GO; GO:0061547; F:glycogen synthase activity, transferring glucose-1-phosphate; TAS:Reactome.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009749; P:response to glucose; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   GZF1_HUMAN              Reviewed;         711 AA.
AC   Q9H116; A8K199; B2RBC3; B3KPL4; D3DW39; Q54A22; Q96N08; Q9BQK9;
AC   Q9H117; Q9H6W6;
DE   RecName: Full=GDNF-inducible zinc finger protein 1;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 23;
DE   AltName: Full=Zinc finger protein 336;
GN   Name=GZF1; Synonyms=ZBTB23, ZNF336;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   H10_HUMAN               Reviewed;         194 AA.
AC   P07305; B2R6I0; B4DRD6; Q6FG88; Q8N6R3;
DE   RecName: Full=Histone H1.0;
DE   AltName: Full=Histone H1';
DE   AltName: Full=Histone H1(0);
DE   Contains:
DE     RecName: Full=Histone H1.0, N-terminally processed;
GN   Name=H1F0; Synonyms=H1FV;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H11_HUMAN               Reviewed;         215 AA.
AC   Q02539; Q3MJ34;
DE   RecName: Full=Histone H1.1;
DE   AltName: Full=Histone H1a;
GN   Name=HIST1H1A; Synonyms=H1F1;
DR   GO; GO:0031490; F:chromatin DNA binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   H12_HUMAN               Reviewed;         213 AA.
AC   P16403; A8K4I2;
DE   RecName: Full=Histone H1.2;
DE   AltName: Full=Histone H1c;
DE   AltName: Full=Histone H1d;
DE   AltName: Full=Histone H1s-1;
GN   Name=HIST1H1C; Synonyms=H1F2;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0016584; P:nucleosome positioning; IEA:Ensembl.
//
ID   H13_HUMAN               Reviewed;         221 AA.
AC   P16402; B2R751; Q2M2I2;
DE   RecName: Full=Histone H1.3;
DE   AltName: Full=Histone H1c;
DE   AltName: Full=Histone H1s-2;
GN   Name=HIST1H1D; Synonyms=H1F3;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0016584; P:nucleosome positioning; IEA:Ensembl.
//
ID   H14_HUMAN               Reviewed;         219 AA.
AC   P10412; Q4VB25;
DE   RecName: Full=Histone H1.4;
DE   AltName: Full=Histone H1b;
DE   AltName: Full=Histone H1s-4;
GN   Name=HIST1H1E; Synonyms=H1F4;
DR   GO; GO:0031490; F:chromatin DNA binding; IMP:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0016584; P:nucleosome positioning; IEA:Ensembl.
//
ID   H15_HUMAN               Reviewed;         226 AA.
AC   P16401; Q14529; Q3MJ42;
DE   RecName: Full=Histone H1.5;
DE   AltName: Full=Histone H1a;
DE   AltName: Full=Histone H1b;
DE   AltName: Full=Histone H1s-3;
GN   Name=HIST1H1B; Synonyms=H1F5;
DR   GO; GO:0031490; F:chromatin DNA binding; IMP:UniProt.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; IMP:UniProt.
DR   GO; GO:0071169; P:establishment of protein localization to chromatin; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProt.
DR   GO; GO:0051574; P:positive regulation of histone H3-K9 methylation; IMP:UniProt.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
//
ID   H17B6_HUMAN             Reviewed;         317 AA.
AC   O14756; O43275;
DE   RecName: Full=17-beta-hydroxysteroid dehydrogenase type 6;
DE            Short=17-beta-HSD 6;
DE            Short=17-beta-HSD6;
DE            EC=1.1.1.105;
DE            EC=1.1.1.239;
DE            EC=1.1.1.62;
DE   AltName: Full=3-alpha->beta-hydroxysteroid epimerase;
DE            Short=3-alpha->beta-HSE;
DE   AltName: Full=Oxidative 3-alpha hydroxysteroid dehydrogenase;
DE   Flags: Precursor;
GN   Name=HSD17B6; Synonyms=RODH;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047035; F:testosterone dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006702; P:androgen biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006710; P:androgen catabolic process; TAS:UniProtKB.
//
ID   H1BP3_HUMAN             Reviewed;         392 AA.
AC   Q53T59; B2RAW2; D6W529; Q86VC2; Q8N367;
DE   RecName: Full=HCLS1-binding protein 3;
DE   AltName: Full=HS1-binding protein 3;
DE            Short=HSP1BP-3;
GN   Name=HS1BP3;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
//
ID   H1AS1_HUMAN             Reviewed;          97 AA.
AC   Q4G0G2;
DE   RecName: Full=Putative uncharacterized protein H1FX-AS1;
DE   AltName: Full=H1FX antisense RNA 1;
GN   Name=H1FX-AS1; Synonyms=C3orf47;
//
ID   H1FNT_HUMAN             Reviewed;         255 AA.
AC   Q75WM6; Q147U8; Q5GKZ5; Q7Z694;
DE   RecName: Full=Testis-specific H1 histone;
DE   AltName: Full=Haploid germ cell-specific nuclear protein 1;
DE   AltName: Full=Histone H1t2;
GN   Name=H1FNT; Synonyms=HANP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0035092; P:sperm chromatin condensation; ISS:UniProtKB.
DR   GO; GO:0007290; P:spermatid nucleus elongation; ISS:UniProtKB.
//
ID   H1FOO_HUMAN             Reviewed;         346 AA.
AC   Q8IZA3; Q86WT7;
DE   RecName: Full=Histone H1oo;
DE   AltName: Full=Oocyte-specific histone H1;
DE   AltName: Full=Oocyte-specific linker histone H1;
DE            Short=osH1;
GN   Name=H1FOO; Synonyms=H1OO, OSH1;
DR   GO; GO:0031492; F:nucleosomal DNA binding; ISS:UniProt.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:2000737; P:negative regulation of stem cell differentiation; ISS:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0016584; P:nucleosome positioning; ISS:UniProt.
DR   GO; GO:0044030; P:regulation of DNA methylation; ISS:UniProt.
//
ID   H1T_HUMAN               Reviewed;         207 AA.
AC   P22492; Q6ISI1; Q8IUE8;
DE   RecName: Full=Histone H1t;
DE   AltName: Full=Testicular H1 histone;
GN   Name=HIST1H1T; Synonyms=H1FT, H1T;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   H1X_HUMAN               Reviewed;         213 AA.
AC   Q92522;
DE   RecName: Full=Histone H1x;
GN   Name=H1FX;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1A_HUMAN             Reviewed;         131 AA.
AC   Q96QV6;
DE   RecName: Full=Histone H2A type 1-A;
DE   AltName: Full=Histone H2A/r;
GN   Name=HIST1H2AA; Synonyms=H2AFR;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1B_HUMAN             Reviewed;         130 AA.
AC   P04908; P28001; Q76P63;
DE   RecName: Full=Histone H2A type 1-B/E;
DE   AltName: Full=Histone H2A.2;
DE   AltName: Full=Histone H2A/a;
DE   AltName: Full=Histone H2A/m;
GN   Name=HIST1H2AB; Synonyms=H2AFM;
GN   and
GN   Name=HIST1H2AE; Synonyms=H2AFA;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1C_HUMAN             Reviewed;         130 AA.
AC   Q93077; B2R4F7; O00775; O00776; O00777; O00778; Q540R1;
DE   RecName: Full=Histone H2A type 1-C;
DE   AltName: Full=Histone H2A/l;
GN   Name=HIST1H2AC; Synonyms=H2AFL;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1D_HUMAN             Reviewed;         130 AA.
AC   P20671; A0PK91; P57754; Q6FGY6;
DE   RecName: Full=Histone H2A type 1-D;
DE   AltName: Full=Histone H2A.3;
DE   AltName: Full=Histone H2A/g;
GN   Name=HIST1H2AD; Synonyms=H2AFG;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1H_HUMAN             Reviewed;         128 AA.
AC   Q96KK5;
DE   RecName: Full=Histone H2A type 1-H;
DE   AltName: Full=Histone H2A/s;
GN   Name=HIST1H2AH; Synonyms=HIST1H2AI;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1J_HUMAN             Reviewed;         128 AA.
AC   Q99878; A2RUU6; Q5JXQ5;
DE   RecName: Full=Histone H2A type 1-J;
DE   AltName: Full=Histone H2A/e;
GN   Name=HIST1H2AJ; Synonyms=H2AFE;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A1_HUMAN              Reviewed;         130 AA.
AC   P0C0S8; P02261; Q2M1R2; Q76PA6;
DE   RecName: Full=Histone H2A type 1;
DE            Short=H2A.1;
DE   AltName: Full=Histone H2A/p;
GN   Name=HIST1H2AG; Synonyms=H2AFP;
GN   and
GN   Name=HIST1H2AI; Synonyms=H2AFC;
GN   and
GN   Name=HIST1H2AK; Synonyms=H2AFD;
GN   and
GN   Name=HIST1H2AL; Synonyms=H2AFI;
GN   and
GN   Name=HIST1H2AM; Synonyms=H2AFN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A2A_HUMAN             Reviewed;         130 AA.
AC   Q6FI13; B2R5F0; P20670;
DE   RecName: Full=Histone H2A type 2-A;
DE   AltName: Full=Histone H2A.2;
DE   AltName: Full=Histone H2A/o;
GN   Name=HIST2H2AA3; Synonyms=H2AFO, HIST2H2AA;
GN   and
GN   Name=HIST2H2AA4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A2B_HUMAN             Reviewed;         130 AA.
AC   Q8IUE6;
DE   RecName: Full=Histone H2A type 2-B;
GN   Name=HIST2H2AB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A2C_HUMAN             Reviewed;         129 AA.
AC   Q16777; Q6DRA7; Q8IUE5;
DE   RecName: Full=Histone H2A type 2-C;
DE   AltName: Full=Histone H2A-GL101;
DE   AltName: Full=Histone H2A/q;
GN   Name=HIST2H2AC; Synonyms=H2AFQ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2A3_HUMAN              Reviewed;         130 AA.
AC   Q7L7L0; B2R4S4;
DE   RecName: Full=Histone H2A type 3;
GN   Name=HIST3H2A;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0006337; P:nucleosome disassembly; IMP:UniProt.
DR   GO; GO:0070914; P:UV-damage excision repair; IMP:UniProt.
//
ID   H2AB1_HUMAN             Reviewed;         115 AA.
AC   P0C5Y9; A0PK90; P98176; Q5TZB2; Q6FG78; Q96PR7;
DE   RecName: Full=Histone H2A-Bbd type 1;
DE   AltName: Full=H2A Barr body-deficient;
DE            Short=H2A.Bbd;
GN   Name=H2AFB1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IMP:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
//
ID   H2AB2_HUMAN             Reviewed;         115 AA.
AC   P0C5Z0; A1L4E4; P98176; Q5TZB2; Q6FG78; Q96PR7;
DE   RecName: Full=Histone H2A-Bbd type 2/3;
DE   AltName: Full=H2A Barr body-deficient;
DE            Short=H2A.Bbd;
GN   Name=H2AFB2;
GN   and
GN   Name=H2AFB3; Synonyms=H2ABBD, H2AFB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IMP:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
//
ID   H2AJ_HUMAN              Reviewed;         129 AA.
AC   Q9BTM1; Q9NV63;
DE   RecName: Full=Histone H2A.J;
DE            Short=H2a/j;
GN   Name=H2AFJ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2AW_HUMAN              Reviewed;         372 AA.
AC   Q9P0M6; Q5SQT2;
DE   RecName: Full=Core histone macro-H2A.2;
DE            Short=Histone macroH2A2;
DE            Short=mH2A2;
GN   Name=H2AFY2; Synonyms=MACROH2A2;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProt.
DR   GO; GO:0007420; P:brain development; IMP:UniProt.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007549; P:dosage compensation; IDA:MGI.
DR   GO; GO:0071169; P:establishment of protein localization to chromatin; IMP:UniProt.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
DR   GO; GO:1901837; P:negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IGI:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2AV_HUMAN              Reviewed;         128 AA.
AC   Q71UI9; A6NFA8; A6NKY0; A6NN01; A8MQC5; Q59GV8; Q6PK98;
DE   RecName: Full=Histone H2A.V;
DE   AltName: Full=H2A.F/Z;
GN   Name=H2AFV; Synonyms=H2AV;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2AX_HUMAN              Reviewed;         143 AA.
AC   P16104; Q4ZGJ7; Q6IAS5;
DE   RecName: Full=Histone H2AX;
DE            Short=H2a/x;
DE   AltName: Full=Histone H2A.X;
GN   Name=H2AFX; Synonyms=H2AX;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:BHF-UCL.
DR   GO; GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; NAS:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; NAS:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   H2AY_HUMAN              Reviewed;         372 AA.
AC   O75367; O75377; Q503A8; Q7Z5E3; Q96D41; Q9H8P3; Q9UP96;
DE   RecName: Full=Core histone macro-H2A.1;
DE            Short=Histone macroH2A1;
DE            Short=mH2A1;
DE   AltName: Full=Histone H2A.y;
DE            Short=H2A/y;
DE   AltName: Full=Medulloblastoma antigen MU-MB-50.205;
GN   Name=H2AFY; Synonyms=MACROH2A1;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0010385; F:double-stranded methylated DNA binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProt.
DR   GO; GO:0030291; F:protein serine/threonine kinase inhibitor activity; IMP:UniProt.
DR   GO; GO:0000182; F:rDNA binding; IDA:UniProt.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProt.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007549; P:dosage compensation; IDA:MGI.
DR   GO; GO:0071169; P:establishment of protein localization to chromatin; IMP:UniProt.
DR   GO; GO:1902750; P:negative regulation of cell cycle G2/M phase transition; IMP:UniProt.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IMP:UniProt.
DR   GO; GO:0033128; P:negative regulation of histone phosphorylation; IMP:UniProt.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
DR   GO; GO:1901837; P:negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2AZ_HUMAN              Reviewed;         128 AA.
AC   P0C0S5; B2RD56; P17317; Q6I9U0;
DE   RecName: Full=Histone H2A.Z;
DE            Short=H2A/z;
GN   Name=H2AFZ; Synonyms=H2AZ;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IMP:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
//
ID   H2B1A_HUMAN             Reviewed;         127 AA.
AC   Q96A08; B2R544; Q6NZ98; Q6NZA0; Q6NZA1;
DE   RecName: Full=Histone H2B type 1-A;
DE   AltName: Full=Histone H2B, testis;
DE            Short=TSH2B.1;
DE   AltName: Full=Testis-specific histone H2B;
GN   Name=HIST1H2BA; Synonyms=TSH2B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0071229; P:cellular response to acid; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0071674; P:mononuclear cell migration; IEA:Ensembl.
DR   GO; GO:0006334; P:nucleosome assembly; ISS:UniProtKB.
DR   GO; GO:0006337; P:nucleosome disassembly; ISS:UniProtKB.
DR   GO; GO:0031639; P:plasminogen activation; IEA:Ensembl.
DR   GO; GO:0051099; P:positive regulation of binding; IEA:Ensembl.
DR   GO; GO:0035093; P:spermatogenesis, exchange of chromosomal proteins; ISS:UniProtKB.
//
ID   H2B1B_HUMAN             Reviewed;         126 AA.
AC   P33778; Q4KN36;
DE   RecName: Full=Histone H2B type 1-B;
DE   AltName: Full=Histone H2B.1;
DE   AltName: Full=Histone H2B.f;
DE            Short=H2B/f;
GN   Name=HIST1H2BB; Synonyms=H2BFF;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1C_HUMAN             Reviewed;         126 AA.
AC   P62807; P02278; Q3B872; Q4VB69; Q93078; Q93080;
DE   RecName: Full=Histone H2B type 1-C/E/F/G/I;
DE   AltName: Full=Histone H2B.1 A;
DE   AltName: Full=Histone H2B.a;
DE            Short=H2B/a;
DE   AltName: Full=Histone H2B.g;
DE            Short=H2B/g;
DE   AltName: Full=Histone H2B.h;
DE            Short=H2B/h;
DE   AltName: Full=Histone H2B.k;
DE            Short=H2B/k;
DE   AltName: Full=Histone H2B.l;
DE            Short=H2B/l;
GN   Name=HIST1H2BC; Synonyms=H2BFL;
GN   and
GN   Name=HIST1H2BE; Synonyms=H2BFH;
GN   and
GN   Name=HIST1H2BF; Synonyms=H2BFG;
GN   and
GN   Name=HIST1H2BG; Synonyms=H2BFA;
GN   and
GN   Name=HIST1H2BI; Synonyms=H2BFK;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1D_HUMAN             Reviewed;         126 AA.
AC   P58876;
DE   RecName: Full=Histone H2B type 1-D;
DE   AltName: Full=HIRA-interacting protein 2;
DE   AltName: Full=Histone H2B.1 B;
DE   AltName: Full=Histone H2B.b;
DE            Short=H2B/b;
GN   Name=HIST1H2BD; Synonyms=H2BFB, HIRIP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2B1H_HUMAN             Reviewed;         126 AA.
AC   Q93079; B2R541; Q4VB74;
DE   RecName: Full=Histone H2B type 1-H;
DE   AltName: Full=Histone H2B.j;
DE            Short=H2B/j;
GN   Name=HIST1H2BH; Synonyms=H2BFJ;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1J_HUMAN             Reviewed;         126 AA.
AC   P06899; B2R4J4; O60816;
DE   RecName: Full=Histone H2B type 1-J;
DE   AltName: Full=Histone H2B.1;
DE   AltName: Full=Histone H2B.r;
DE            Short=H2B/r;
GN   Name=HIST1H2BJ; Synonyms=H2BFR;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1K_HUMAN             Reviewed;         126 AA.
AC   O60814; A8K7P7; Q2VPI7;
DE   RecName: Full=Histone H2B type 1-K;
DE            Short=H2B K;
DE   AltName: Full=HIRA-interacting protein 1;
GN   Name=HIST1H2BK; Synonyms=H2BFT, HIRIP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2B1L_HUMAN             Reviewed;         126 AA.
AC   Q99880; B2R5A3; Q52LW9;
DE   RecName: Full=Histone H2B type 1-L;
DE   AltName: Full=Histone H2B.c;
DE            Short=H2B/c;
GN   Name=HIST1H2BL; Synonyms=H2BFC;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1M_HUMAN             Reviewed;         126 AA.
AC   Q99879; Q6NWQ3;
DE   RecName: Full=Histone H2B type 1-M;
DE   AltName: Full=Histone H2B.e;
DE            Short=H2B/e;
GN   Name=HIST1H2BM; Synonyms=H2BFE;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1N_HUMAN             Reviewed;         126 AA.
AC   Q99877; B2R5L4; Q494S8; Q96FB7;
DE   RecName: Full=Histone H2B type 1-N;
DE   AltName: Full=Histone H2B.d;
DE            Short=H2B/d;
GN   Name=HIST1H2BN; Synonyms=H2BFD;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B1O_HUMAN             Reviewed;         126 AA.
AC   P23527; Q3KPI7; Q8TCV6;
DE   RecName: Full=Histone H2B type 1-O;
DE   AltName: Full=Histone H2B.2;
DE   AltName: Full=Histone H2B.n;
DE            Short=H2B/n;
GN   Name=HIST1H2BO; Synonyms=H2BFH, H2BFN;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B2C_HUMAN             Reviewed;         193 AA.
AC   Q6DN03; B7Z677;
DE   RecName: Full=Putative histone H2B type 2-C;
DE   AltName: Full=Histone H2B.t;
DE            Short=H2B/t;
GN   Name=HIST2H2BC;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2B2D_HUMAN             Reviewed;         164 AA.
AC   Q6DRA6;
DE   RecName: Full=Putative histone H2B type 2-D;
GN   Name=HIST2H2BD;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2B2E_HUMAN             Reviewed;         126 AA.
AC   Q16778; A3KMC7; A8K110; Q4KMY1; Q5QNX0; Q9UE88;
DE   RecName: Full=Histone H2B type 2-E;
DE   AltName: Full=Histone H2B-GL105;
DE   AltName: Full=Histone H2B.q;
DE            Short=H2B/q;
GN   Name=HIST2H2BE; Synonyms=H2BFQ;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
//
ID   H2B2F_HUMAN             Reviewed;         126 AA.
AC   Q5QNW6; A8K0U9; B4DLA9;
DE   RecName: Full=Histone H2B type 2-F;
GN   Name=HIST2H2BF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2B3B_HUMAN             Reviewed;         126 AA.
AC   Q8N257; A4FU05; Q3ZCP6; Q5TA30;
DE   RecName: Full=Histone H2B type 3-B;
DE   AltName: Full=H2B type 12;
GN   Name=HIST3H2BB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2BFS_HUMAN             Reviewed;         126 AA.
AC   P57053; A0AVF9; Q5R2W0;
DE   RecName: Full=Histone H2B type F-S;
DE   AltName: Full=Histone H2B.s;
DE            Short=H2B/s;
GN   Name=H2BFS;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   H2BFM_HUMAN             Reviewed;         154 AA.
AC   P0C1H6; A6NP82;
DE   RecName: Full=Histone H2B type F-M;
DE   AltName: Full=Histone H2B.s;
DE            Short=H2B/s;
GN   Name=H2BFM;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H2BWT_HUMAN             Reviewed;         175 AA.
AC   Q7Z2G1; B1AK72; Q147W3;
DE   RecName: Full=Histone H2B type W-T;
DE   AltName: Full=H2B histone family member W testis-specific;
GN   Name=H2BFWT;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H31T_HUMAN              Reviewed;         136 AA.
AC   Q16695; B2R5K3; Q6FGU4;
DE   RecName: Full=Histone H3.1t;
DE            Short=H3/t;
DE            Short=H3t;
DE   AltName: Full=H3/g;
GN   Name=HIST3H3; Synonyms=H3FT;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
//
ID   H31_HUMAN               Reviewed;         136 AA.
AC   P68431; A0PJT7; A5PLR1; P02295; P02296; P16106; Q6ISV8; Q6NWP8;
AC   Q6NWP9; Q6NXU4; Q71DJ3; Q93081;
DE   RecName: Full=Histone H3.1;
DE   AltName: Full=Histone H3/a;
DE   AltName: Full=Histone H3/b;
DE   AltName: Full=Histone H3/c;
DE   AltName: Full=Histone H3/d;
DE   AltName: Full=Histone H3/f;
DE   AltName: Full=Histone H3/h;
DE   AltName: Full=Histone H3/i;
DE   AltName: Full=Histone H3/j;
DE   AltName: Full=Histone H3/k;
DE   AltName: Full=Histone H3/l;
GN   Name=HIST1H3A; Synonyms=H3FA;
GN   and
GN   Name=HIST1H3B; Synonyms=H3FL;
GN   and
GN   Name=HIST1H3C; Synonyms=H3FC;
GN   and
GN   Name=HIST1H3D; Synonyms=H3FB;
GN   and
GN   Name=HIST1H3E; Synonyms=H3FD;
GN   and
GN   Name=HIST1H3F; Synonyms=H3FI;
GN   and
GN   Name=HIST1H3G; Synonyms=H3FH;
GN   and
GN   Name=HIST1H3H; Synonyms=H3FK;
GN   and
GN   Name=HIST1H3I; Synonyms=H3FF;
GN   and
GN   Name=HIST1H3J; Synonyms=H3FJ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0060968; P:regulation of gene silencing; IDA:BHF-UCL.
//
ID   H32_HUMAN               Reviewed;         136 AA.
AC   Q71DI3; A2BDF6; A6NFS4; Q6B053;
DE   RecName: Full=Histone H3.2;
DE   AltName: Full=Histone H3/m;
DE   AltName: Full=Histone H3/o;
GN   Name=HIST2H3A;
GN   and
GN   Name=HIST2H3C; Synonyms=H3F2, H3FM;
GN   and
GN   Name=HIST2H3D;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H33_HUMAN               Reviewed;         136 AA.
AC   P84243; P06351; P33155; Q5VV55; Q5VV56; Q66I33; Q9V3W4;
DE   RecName: Full=Histone H3.3;
GN   Name=H3F3A; Synonyms=H3.3A, H3F3; ORFNames=PP781;
GN   and
GN   Name=H3F3B; Synonyms=H3.3B;
DR   GO; GO:0031492; F:nucleosomal DNA binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProt.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
//
ID   H3C_HUMAN               Reviewed;         135 AA.
AC   Q6NXT2; E9P281;
DE   RecName: Full=Histone H3.3C;
DE   AltName: Full=Histone H3.5;
GN   Name=H3F3C;
DR   GO; GO:0031492; F:nucleosomal DNA binding; IDA:UniProt.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProt.
//
ID   H4G_HUMAN               Reviewed;          98 AA.
AC   Q99525;
DE   RecName: Full=Histone H4-like protein type G;
GN   Name=HIST1H4G; Synonyms=H4/L, H4FL;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   H4_HUMAN                Reviewed;         103 AA.
AC   P62805; A2VCL0; P02304; P02305; Q6DRA9; Q6FGB8; Q6NWP7;
DE   RecName: Full=Histone H4;
GN   Name=HIST1H4A; Synonyms=H4/A, H4FA;
GN   and
GN   Name=HIST1H4B; Synonyms=H4/I, H4FI;
GN   and
GN   Name=HIST1H4C; Synonyms=H4/G, H4FG;
GN   and
GN   Name=HIST1H4D; Synonyms=H4/B, H4FB;
GN   and
GN   Name=HIST1H4E; Synonyms=H4/J, H4FJ;
GN   and
GN   Name=HIST1H4F; Synonyms=H4/C, H4FC;
GN   and
GN   Name=HIST1H4H; Synonyms=H4/H, H4FH;
GN   and
GN   Name=HIST1H4I; Synonyms=H4/M, H4FM;
GN   and
GN   Name=HIST1H4J; Synonyms=H4/E, H4FE;
GN   and
GN   Name=HIST1H4K; Synonyms=H4/D, H4FD;
GN   and
GN   Name=HIST1H4L; Synonyms=H4/K, H4FK;
GN   and
GN   Name=HIST2H4A; Synonyms=H4/N, H4F2, H4FN, HIST2H4;
GN   and
GN   Name=HIST2H4B; Synonyms=H4/O, H4FO;
GN   and
GN   Name=HIST4H4;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0035575; F:histone demethylase activity (H4-K20 specific); TAS:Reactome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0035574; P:histone H4-K20 demethylation; TAS:GOC.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045653; P:negative regulation of megakaryocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
//
ID   H6ST1_HUMAN             Reviewed;         411 AA.
AC   O60243; B4DEP2; B4DJ29; Q53SL2; Q9BVI1;
DE   RecName: Full=Heparan-sulfate 6-O-sulfotransferase 1;
DE            Short=HS6ST-1;
DE            EC=2.8.2.-;
GN   Name=HS6ST1; Synonyms=HS6ST;
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015015; P:heparan sulfate proteoglycan biosynthetic process, enzymatic modification; TAS:ProtInc.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   H6ST2_HUMAN             Reviewed;         605 AA.
AC   Q96MM7; B9WRT4; B9WRT5; E9PDY5; Q2TB13; Q4VC07; Q6PIC4; Q86SM9;
AC   Q8N3T4; Q8NBN4; Q96SJ4;
DE   RecName: Full=Heparan-sulfate 6-O-sulfotransferase 2;
DE            Short=HS6ST-2;
DE            EC=2.8.2.-;
GN   Name=HS6ST2; ORFNames=PSEC0092;
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   H6ST3_HUMAN             Reviewed;         471 AA.
AC   Q8IZP7; Q5W0L0; Q68CW6;
DE   RecName: Full=Heparan-sulfate 6-O-sulfotransferase 3;
DE            Short=HS6ST-3;
DE            EC=2.8.2.-;
GN   Name=HS6ST3;
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
//
ID   H90B2_HUMAN             Reviewed;         381 AA.
AC   Q58FF8;
DE   RecName: Full=Putative heat shock protein HSP 90-beta 2;
DE   AltName: Full=Heat shock protein 90-beta b;
DE            Short=Heat shock protein 90Bb;
GN   Name=HSP90AB2P; Synonyms=HSP90BB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   H90B3_HUMAN             Reviewed;         597 AA.
AC   Q58FF7;
DE   RecName: Full=Putative heat shock protein HSP 90-beta-3;
DE   AltName: Full=Heat shock protein 90-beta c;
DE            Short=Heat shock protein 90Bc;
GN   Name=HSP90AB3P; Synonyms=HSP90BC;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   H90B4_HUMAN             Reviewed;         505 AA.
AC   Q58FF6;
DE   RecName: Full=Putative heat shock protein HSP 90-beta 4;
GN   Name=HSP90AB4P;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HABP2_HUMAN             Reviewed;         560 AA.
AC   Q14520; A8K467; B7Z8U5; F5H5M6; O00663;
DE   RecName: Full=Hyaluronan-binding protein 2;
DE            EC=3.4.21.-;
DE   AltName: Full=Factor VII-activating protease;
DE   AltName: Full=Factor seven-activating protease;
DE            Short=FSAP;
DE   AltName: Full=Hepatocyte growth factor activator-like protein;
DE   AltName: Full=Plasma hyaluronan-binding protein;
DE   Contains:
DE     RecName: Full=Hyaluronan-binding protein 2 50 kDa heavy chain;
DE   Contains:
DE     RecName: Full=Hyaluronan-binding protein 2 50 kDa heavy chain alternate form;
DE   Contains:
DE     RecName: Full=Hyaluronan-binding protein 2 27 kDa light chain;
DE   Contains:
DE     RecName: Full=Hyaluronan-binding protein 2 27 kDa light chain alternate form;
DE   Flags: Precursor;
GN   Name=HABP2; Synonyms=HGFAL, PHBP;
DR   GO; GO:0005539; F:glycosaminoglycan binding; TAS:ProtInc.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
//
ID   HABP4_HUMAN             Reviewed;         413 AA.
AC   Q5JVS0; O75804; Q8WV33; Q9NYJ2;
DE   RecName: Full=Intracellular hyaluronan-binding protein 4;
DE            Short=IHABP-4;
DE            Short=IHABP4;
DE   AltName: Full=Ki-1/57 intracellular antigen;
GN   Name=HABP4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HACD1_HUMAN             Reviewed;         288 AA.
AC   B0YJ81; B0YJ80; Q6JIC5; Q96FW7; Q9HB93; Q9UHX2;
DE   RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1;
DE            EC=4.2.1.134;
DE   AltName: Full=3-hydroxyacyl-CoA dehydratase 1;
DE            Short=HACD1;
DE   AltName: Full=Cementum attachment protein;
DE   AltName: Full=Protein-tyrosine phosphatase-like member A;
GN   Name=PTPLA; Synonyms=HACD1;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   HACD2_HUMAN             Reviewed;         254 AA.
AC   Q6Y1H2;
DE   RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2;
DE            EC=4.2.1.134;
DE   AltName: Full=3-hydroxyacyl-CoA dehydratase 2;
DE            Short=HACD2;
DE   AltName: Full=Protein-tyrosine phosphatase-like member B;
GN   Name=PTPLB; Synonyms=HACD2;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
//
ID   HACD3_HUMAN             Reviewed;         362 AA.
AC   Q9P035; A0PJA1; Q280Z3; Q6PD63; Q8IUI5; Q8NC86; Q8NCB1; Q96T12;
AC   Q9NQA7;
DE   RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3;
DE            EC=4.2.1.134;
DE   AltName: Full=3-hydroxyacyl-CoA dehydratase 3;
DE            Short=HACD3;
DE   AltName: Full=Butyrate-induced protein 1;
DE            Short=B-ind1;
DE            Short=hB-ind1;
DE   AltName: Full=Protein tyrosine phosphatase-like protein PTPLAD1;
DE   AltName: Full=Protein-tyrosine phosphatase-like A domain-containing protein 1;
GN   Name=PTPLAD1; Synonyms=BIND1, HACD3;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0016601; P:Rac protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   HACD4_HUMAN             Reviewed;         232 AA.
AC   Q5VWC8; Q7Z385;
DE   RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 4;
DE            EC=4.2.1.134;
DE   AltName: Full=3-hydroxyacyl-CoA dehydratase 4;
DE            Short=HACD4;
DE   AltName: Full=Protein tyrosine phosphatase-like protein PTPLAD2;
DE   AltName: Full=Protein-tyrosine phosphatase-like A domain-containing protein 2;
GN   Name=PTPLAD2; Synonyms=HACD4;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
//
ID   HACE1_HUMAN             Reviewed;         909 AA.
AC   Q8IYU2; A8K6U5; B3KY89; B4DFM6; B4DTQ4; B7Z9X6; E9PGP0; Q5VU99;
AC   Q5VUA0; Q8ND12; Q9P2M6;
DE   RecName: Full=E3 ubiquitin-protein ligase HACE1;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1;
GN   Name=HACE1; Synonyms=KIAA1320;
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007030; P:Golgi organization; IDA:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; IMP:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016601; P:Rac protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HACL1_HUMAN             Reviewed;         578 AA.
AC   Q9UJ83; B4DWI1; B4DXI5; E9PEN4; Q9BV42; Q9P0A2;
DE   RecName: Full=2-hydroxyacyl-CoA lyase 1;
DE            EC=4.1.-.-;
DE   AltName: Full=2-hydroxyphytanoyl-CoA lyase;
DE            Short=2-HPCL;
DE   AltName: Full=Phytanoyl-CoA 2-hydroxylase 2;
GN   Name=HACL1; Synonyms=HPCL, HPCL2, PHYH2; ORFNames=HSPC279;
DR   GO; GO:0016830; F:carbon-carbon lyase activity; IDA:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; IDA:HGNC.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HAIR_HUMAN              Reviewed;        1189 AA.
AC   O43593; Q6GS30; Q96H33; Q9NPE1;
DE   RecName: Full=Lysine-specific demethylase hairless;
DE            EC=1.14.11.-;
GN   Name=HR;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HAGHL_HUMAN             Reviewed;         290 AA.
AC   Q6PII5; A6NCC4; D3DU64; Q59FX8; Q96BZ3; Q96NR5; Q96S11; Q9BT45;
DE   RecName: Full=Hydroxyacylglutathione hydrolase-like protein;
DE            EC=3.1.2.-;
GN   Name=HAGHL;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   HAKAI_HUMAN             Reviewed;         491 AA.
AC   Q75N03; B7ZM03; Q8TAJ4; Q9H5S6;
DE   RecName: Full=E3 ubiquitin-protein ligase Hakai;
DE            EC=6.3.2.-;
DE   AltName: Full=Casitas B-lineage lymphoma-transforming sequence-like protein 1;
DE   AltName: Full=RING finger protein 188;
DE   AltName: Full=c-Cbl-like protein 1;
GN   Name=CBLL1; Synonyms=HAKAI, RNF188;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0045807; P:positive regulation of endocytosis; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:UniProtKB.
//
ID   HAND1_HUMAN             Reviewed;         215 AA.
AC   O96004;
DE   RecName: Full=Heart- and neural crest derivatives-expressed protein 1;
DE   AltName: Full=Class A basic helix-loop-helix protein 27;
DE            Short=bHLHa27;
DE   AltName: Full=Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1;
DE            Short=eHAND;
GN   Name=HAND1; Synonyms=BHLHA27, EHAND;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0001824; P:blastocyst development; IEP:BHF-UCL.
DR   GO; GO:0003218; P:cardiac left ventricle formation; IMP:BHF-UCL.
DR   GO; GO:0003219; P:cardiac right ventricle formation; IMP:BHF-UCL.
DR   GO; GO:0060411; P:cardiac septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0035050; P:embryonic heart tube development; ISS:BHF-UCL.
DR   GO; GO:0003144; P:embryonic heart tube formation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0060485; P:mesenchyme development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEP:BHF-UCL.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   HAND2_HUMAN             Reviewed;         217 AA.
AC   P61296; B6ECG9; O95300; O95301; P97833;
DE   RecName: Full=Heart- and neural crest derivatives-expressed protein 2;
DE   AltName: Full=Class A basic helix-loop-helix protein 26;
DE            Short=bHLHa26;
DE   AltName: Full=Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2;
DE            Short=dHAND;
GN   Name=HAND2; Synonyms=BHLHA26, DHAND;
DR   GO; GO:0033613; F:activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0003680; F:AT DNA binding; IDA:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0007512; P:adult heart development; IEP:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0003278; P:apoptotic process involved in heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0061309; P:cardiac neural crest cell development involved in outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003253; P:cardiac neural crest cell migration involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0003219; P:cardiac right ventricle formation; IEA:Ensembl.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0061325; P:cell proliferation involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0060982; P:coronary artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; NAS:UniProtKB.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0010463; P:mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0014032; P:neural crest cell development; ISS:BHF-UCL.
DR   GO; GO:0003357; P:noradrenergic neuron differentiation; NAS:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; IEA:Ensembl.
DR   GO; GO:2000764; P:positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000763; P:positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0003266; P:regulation of secondary heart field cardioblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; ISS:BHF-UCL.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0061032; P:visceral serous pericardium development; IEA:Ensembl.
//
ID   HAOX1_HUMAN             Reviewed;         370 AA.
AC   Q9UJM8; Q14CQ0; Q9UPZ0; Q9Y3I7;
DE   RecName: Full=Hydroxyacid oxidase 1;
DE            Short=HAOX1;
DE            EC=1.1.3.15;
DE   AltName: Full=Glycolate oxidase;
DE            Short=GOX;
GN   Name=HAO1; Synonyms=GOX1, HAOX1;
DR   GO; GO:0003973; F:(S)-2-hydroxy-acid oxidase activity; IDA:UniProtKB.
DR   GO; GO:0010181; F:FMN binding; IDA:UniProtKB.
DR   GO; GO:0008891; F:glycolate oxidase activity; IDA:UniProtKB.
DR   GO; GO:0047969; F:glyoxylate oxidase activity; TAS:Reactome.
DR   GO; GO:0052853; F:long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052854; F:medium-chain-(S)-2-hydroxy-acid oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0052852; F:very-long-chain-(S)-2-hydroxy-acid oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; IDA:UniProtKB.
DR   GO; GO:0046296; P:glycolate catabolic process; IDA:UniProtKB.
DR   GO; GO:0046487; P:glyoxylate metabolic process; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HAOX2_HUMAN             Reviewed;         351 AA.
AC   Q9NYQ3; Q2TU86; Q9UJS6;
DE   RecName: Full=Hydroxyacid oxidase 2;
DE            Short=HAOX2;
DE            EC=1.1.3.15;
DE   AltName: Full=(S)-2-hydroxy-acid oxidase, peroxisomal;
DE   AltName: Full=Cell growth-inhibiting gene 16 protein;
DE   AltName: Full=Long chain alpha-hydroxy acid oxidase;
DE   AltName: Full=Long-chain L-2-hydroxy acid oxidase;
GN   Name=HAO2; Synonyms=HAOX2; ORFNames=GIG16;
DR   GO; GO:0003973; F:(S)-2-hydroxy-acid oxidase activity; IDA:UniProtKB.
DR   GO; GO:0010181; F:FMN binding; IEA:Ensembl.
DR   GO; GO:0052853; F:long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity; IDA:UniProtKB.
DR   GO; GO:0052854; F:medium-chain-(S)-2-hydroxy-acid oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0052852; F:very-long-chain-(S)-2-hydroxy-acid oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019395; P:fatty acid oxidation; IDA:UniProtKB.
DR   GO; GO:0018924; P:mandelate metabolic process; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
//
ID   HAP1_HUMAN              Reviewed;         671 AA.
AC   P54257; A8MQB5; O75358; Q59GK4; Q9H4G3; Q9HA98; Q9NY90;
DE   RecName: Full=Huntingtin-associated protein 1;
DE            Short=HAP-1;
DE   AltName: Full=Neuroan 1;
GN   Name=HAP1; Synonyms=HAP2, HLP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; NAS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IEA:Ensembl.
//
ID   HAP28_HUMAN             Reviewed;         181 AA.
AC   Q13442; D6W5S5; Q92906;
DE   RecName: Full=28 kDa heat- and acid-stable phosphoprotein;
DE   AltName: Full=PDGF-associated protein;
DE            Short=PAP;
DE   AltName: Full=PDGFA-associated protein 1;
DE            Short=PAP1;
GN   Name=PDAP1; Synonyms=HASPP28;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   HARB1_HUMAN             Reviewed;         349 AA.
AC   Q96MB7; D3DQP9;
DE   RecName: Full=Putative nuclease HARBI1;
DE            EC=3.1.-.-;
DE   AltName: Full=Harbinger transposase-derived nuclease;
GN   Name=HARBI1; Synonyms=C11orf77;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
//
ID   HASP_HUMAN              Reviewed;         798 AA.
AC   Q8TF76; Q5U5K3; Q96MN1; Q9BXS7;
DE   RecName: Full=Serine/threonine-protein kinase haspin;
DE            EC=2.7.11.1;
DE   AltName: Full=Germ cell-specific gene 2 protein;
DE   AltName: Full=H-haspin;
DE   AltName: Full=Haploid germ cell-specific nuclear protein kinase;
GN   Name=GSG2;
DR   GuidetoPHARMACOLOGY; 2028; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0072354; F:histone kinase activity (H3-T3 specific); IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:2000751; P:histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0071459; P:protein localization to chromosome, centromeric region; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0090231; P:regulation of spindle checkpoint; IMP:UniProtKB.
//
ID   HAT1_HUMAN              Reviewed;         419 AA.
AC   O14929; Q49A44; Q53QF0; Q53SU4; Q6P594; Q8WWB9;
DE   RecName: Full=Histone acetyltransferase type B catalytic subunit;
DE            EC=2.3.1.48;
DE   AltName: Full=Histone acetyltransferase 1;
GN   Name=HAT1; Synonyms=KAT1;
DR   GO; GO:0004402; F:histone acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006348; P:chromatin silencing at telomere; IEA:InterPro.
DR   GO; GO:0006323; P:DNA packaging; TAS:ProtInc.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; TAS:ProtInc.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   HAUS1_HUMAN             Reviewed;         278 AA.
AC   Q96CS2; B2RDM7; Q8N837;
DE   RecName: Full=HAUS augmin-like complex subunit 1;
DE   AltName: Full=Coiled-coil domain-containing protein 5;
DE   AltName: Full=Enhancer of invasion-cluster;
DE            Short=HEI-C;
GN   Name=HAUS1; Synonyms=CCDC5, HEIC;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS3_HUMAN             Reviewed;         603 AA.
AC   Q68CZ6; O43606; Q8TAZ5; Q9BTJ9;
DE   RecName: Full=HAUS augmin-like complex subunit 3;
GN   Name=HAUS3; Synonyms=C4orf15;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS2_HUMAN             Reviewed;         235 AA.
AC   Q9NVX0; C9JH36; Q9H9B3;
DE   RecName: Full=HAUS augmin-like complex subunit 2;
DE   AltName: Full=Centrosomal protein of 27 kDa;
DE            Short=Cep27;
GN   Name=HAUS2; Synonyms=C15orf25, CEP27;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS5_HUMAN             Reviewed;         633 AA.
AC   O94927; B2RXK1; Q6P2P7; Q7L3D5; Q96CT8;
DE   RecName: Full=HAUS augmin-like complex subunit 5;
GN   Name=HAUS5; Synonyms=KIAA0841;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS6_HUMAN             Reviewed;         955 AA.
AC   Q7Z4H7; B3KPK4; B4DX82; Q05CG1; Q14CB6; Q14CD9; Q2TA91; Q6IQ10;
AC   Q6NZX5; Q8IZQ4; Q96FN0; Q9H950; Q9H998; Q9HCJ8; Q9NXT8;
DE   RecName: Full=HAUS augmin-like complex subunit 6;
GN   Name=HAUS6; Synonyms=DGT6, FAM29A, KIAA1574;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS4_HUMAN             Reviewed;         363 AA.
AC   Q9H6D7; B7WP17; D3DS34; Q86T15; Q86T16; Q86U43; Q9NX59;
DE   RecName: Full=HAUS augmin-like complex subunit 4;
GN   Name=HAUS4; Synonyms=C14orf94;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS7_HUMAN             Reviewed;         368 AA.
AC   Q99871; B4DUH6; D3DWT9; Q96HS8; Q9NP54; Q9UFH9;
DE   RecName: Full=HAUS augmin-like complex subunit 7;
DE   AltName: Full=26S proteasome-associated UCH37-interacting protein 1;
DE   AltName: Full=UCHL5-interacting protein;
DE   AltName: Full=X-linked protein STS1769;
GN   Name=HAUS7; Synonyms=UCHL5IP, UIP1;
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAUS8_HUMAN             Reviewed;         410 AA.
AC   Q9BT25; B4DJA7; C9JBZ4; Q49AC4; Q86WF0; Q96FX3;
DE   RecName: Full=HAUS augmin-like complex subunit 8;
DE   AltName: Full=HEC1/NDC80-interacting centrosome-associated protein 1;
DE   AltName: Full=Sarcoma antigen NY-SAR-48;
GN   Name=HAUS8; Synonyms=HICE1;
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   HAVR1_HUMAN             Reviewed;         359 AA.
AC   Q96D42; O43656;
DE   RecName: Full=Hepatitis A virus cellular receptor 1;
DE            Short=HAVcr-1;
DE   AltName: Full=Kidney injury molecule 1;
DE            Short=KIM-1;
DE   AltName: Full=T-cell immunoglobulin and mucin domain-containing protein 1;
DE            Short=TIMD-1;
DE   AltName: Full=T-cell immunoglobulin mucin receptor 1;
DE            Short=TIM;
DE            Short=TIM-1;
DE   AltName: Full=T-cell membrane protein 1;
DE   Flags: Precursor;
GN   Name=HAVCR1; Synonyms=KIM1, TIM1, TIMD1;
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HAVR2_HUMAN             Reviewed;         301 AA.
AC   Q8TDQ0; B2RAY2; Q8WW60; Q96K94;
DE   RecName: Full=Hepatitis A virus cellular receptor 2;
DE            Short=HAVcr-2;
DE   AltName: Full=T-cell immunoglobulin and mucin domain-containing protein 3;
DE            Short=TIMD-3;
DE   AltName: Full=T-cell immunoglobulin mucin receptor 3;
DE            Short=TIM-3;
DE   AltName: Full=T-cell membrane protein 3;
DE   Flags: Precursor;
GN   Name=HAVCR2; Synonyms=TIM3, TIMD3;
//
ID   HAX1_HUMAN              Reviewed;         279 AA.
AC   O00165; A8W4W9; A8W4X0; B4DUJ7; Q5VYD5; Q5VYD7; Q96AU4; Q9BS80;
DE   RecName: Full=HCLS1-associated protein X-1;
DE   AltName: Full=HS1-associating protein X-1;
DE            Short=HAX-1;
DE   AltName: Full=HS1-binding protein 1;
DE            Short=HSP1BP-1;
GN   Name=HAX1; Synonyms=HS1BP1;
DR   GO; GO:0019966; F:interleukin-1 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IDA:UniProtKB.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IMP:BHF-UCL.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:BHF-UCL.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IMP:BHF-UCL.
//
ID   HBAP1_HUMAN             Reviewed;         488 AA.
AC   Q96EW2; Q6P476; Q8N8J4; Q8NHH6; Q8WWF0;
DE   RecName: Full=HSPB1-associated protein 1;
DE   AltName: Full=27 kDa heat shock protein-associated protein 1;
DE   AltName: Full=Protein associated with small stress protein 1;
GN   Name=HSPBAP1; Synonyms=PASS1;
//
ID   HBAT_HUMAN              Reviewed;         142 AA.
AC   P09105; Q13723; Q1W6G5;
DE   RecName: Full=Hemoglobin subunit theta-1;
DE   AltName: Full=Hemoglobin theta-1 chain;
DE   AltName: Full=Theta-1-globin;
GN   Name=HBQ1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015671; P:oxygen transport; TAS:ProtInc.
//
ID   HBAZ_HUMAN              Reviewed;         142 AA.
AC   P02008; Q6IBF6;
DE   RecName: Full=Hemoglobin subunit zeta;
DE   AltName: Full=HBAZ;
DE   AltName: Full=Hemoglobin zeta chain;
DE   AltName: Full=Zeta-globin;
GN   Name=HBZ; Synonyms=HBZ2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   HBA_HUMAN               Reviewed;         142 AA.
AC   P69905; P01922; Q1HDT5; Q3MIF5; Q53F97; Q96KF1; Q9NYR7; Q9UCM0;
DE   RecName: Full=Hemoglobin subunit alpha;
DE   AltName: Full=Alpha-globin;
DE   AltName: Full=Hemoglobin alpha chain;
GN   Name=HBA1;
GN   and
GN   Name=HBA2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0015671; P:oxygen transport; TAS:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IDA:BHF-UCL.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HBB_HUMAN               Reviewed;         147 AA.
AC   P68871; A4GX73; B2ZUE0; P02023; Q13852; Q14481; Q14510; Q45KT0;
AC   Q549N7; Q6FI08; Q6R7N2; Q8IZI1; Q9BX96; Q9UCD6; Q9UCP8; Q9UCP9;
DE   RecName: Full=Hemoglobin subunit beta;
DE   AltName: Full=Beta-globin;
DE   AltName: Full=Hemoglobin beta chain;
DE   Contains:
DE     RecName: Full=LVV-hemorphin-7;
DE   Contains:
DE     RecName: Full=Spinorphin;
GN   Name=HBB;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0030492; F:hemoglobin binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IDA:UniProtKB.
DR   GO; GO:0005344; F:oxygen transporter activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0030185; P:nitric oxide transport; NAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0015671; P:oxygen transport; NAS:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IDA:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:UniProtKB-KW.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:UniProtKB-KW.
DR   GO; GO:0070293; P:renal absorption; IMP:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HBD_HUMAN               Reviewed;         147 AA.
AC   P02042; Q3Y5H3; Q8WXT7;
DE   RecName: Full=Hemoglobin subunit delta;
DE   AltName: Full=Delta-globin;
DE   AltName: Full=Hemoglobin delta chain;
GN   Name=HBD;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
//
ID   HBEGF_HUMAN             Reviewed;         208 AA.
AC   Q99075; B2R821;
DE   RecName: Full=Proheparin-binding EGF-like growth factor;
DE   Contains:
DE     RecName: Full=Heparin-binding EGF-like growth factor;
DE              Short=HB-EGF;
DE              Short=HBEGF;
DE     AltName: Full=Diphtheria toxin receptor;
DE              Short=DT-R;
DE   Flags: Precursor;
GN   Name=HBEGF; Synonyms=DTR, DTS, HEGFL;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; TAS:ProtInc.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IMP:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0051545; P:negative regulation of elastin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0051549; P:positive regulation of keratinocyte migration; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0090303; P:positive regulation of wound healing; IMP:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IEA:Ensembl.
//
ID   HBE_HUMAN               Reviewed;         147 AA.
AC   P02100; Q6FH44;
DE   RecName: Full=Hemoglobin subunit epsilon;
DE   AltName: Full=Epsilon-globin;
DE   AltName: Full=Hemoglobin epsilon chain;
GN   Name=HBE1; Synonyms=HBE;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
//
ID   HBG1_HUMAN              Reviewed;         147 AA.
AC   P69891; P02096; P62027; Q549G1; Q8TDA1; Q96FH7;
DE   RecName: Full=Hemoglobin subunit gamma-1;
DE   AltName: Full=Gamma-1-globin;
DE   AltName: Full=Hb F Agamma;
DE   AltName: Full=Hemoglobin gamma-1 chain;
DE   AltName: Full=Hemoglobin gamma-A chain;
GN   Name=HBG1; ORFNames=PRO2979;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
//
ID   HBG2_HUMAN              Reviewed;         147 AA.
AC   P69892; A8MZE0; P02096; P62027; Q14491; Q68NH9; Q96FH6; Q96FH7;
DE   RecName: Full=Hemoglobin subunit gamma-2;
DE   AltName: Full=Gamma-2-globin;
DE   AltName: Full=Hb F Ggamma;
DE   AltName: Full=Hemoglobin gamma-2 chain;
DE   AltName: Full=Hemoglobin gamma-G chain;
GN   Name=HBG2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
//
ID   HBM_HUMAN               Reviewed;         141 AA.
AC   Q6B0K9;
DE   RecName: Full=Hemoglobin subunit mu;
DE   AltName: Full=Hemoglobin mu chain;
DE   AltName: Full=Mu-globin;
GN   Name=HBM; Synonyms=HBAP2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
//
ID   HBP1_HUMAN              Reviewed;         514 AA.
AC   O60381; B3KVB7; Q8TBM1; Q8TE93; Q96AJ2;
DE   RecName: Full=HMG box-containing protein 1;
DE   AltName: Full=HMG box transcription factor 1;
DE   AltName: Full=High mobility group box transcription factor 1;
GN   Name=HBP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0007050; P:cell cycle arrest; NAS:UniProtKB.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   HBS1L_HUMAN             Reviewed;         684 AA.
AC   Q9Y450; B7Z365; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3;
DE   RecName: Full=HBS1-like protein;
DE   AltName: Full=ERFS;
GN   Name=HBS1L; Synonyms=HBS1, KIAA1038;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   HCAR1_HUMAN             Reviewed;         346 AA.
AC   Q9BXC0; B2R9X4; Q3Y5J3; Q4VBN1; Q6NXU5;
DE   RecName: Full=Hydroxycarboxylic acid receptor 1;
DE   AltName: Full=G-protein coupled receptor 104;
DE   AltName: Full=G-protein coupled receptor 81;
GN   Name=HCAR1; Synonyms=GPR104, GPR81, HCA1; ORFNames=FKSG80;
DR   GuidetoPHARMACOLOGY; 311; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
//
ID   HCAR2_HUMAN             Reviewed;         363 AA.
AC   Q8TDS4; A0PJL5; A7LGG3;
DE   RecName: Full=Hydroxycarboxylic acid receptor 2;
DE   AltName: Full=G-protein coupled receptor 109A;
DE   AltName: Full=G-protein coupled receptor HM74A;
DE   AltName: Full=Niacin receptor 1;
DE   AltName: Full=Nicotinic acid receptor;
GN   Name=HCAR2; Synonyms=GPR109A, HCA2, HM74A, NIACR1;
DR   GuidetoPHARMACOLOGY; 312; -.
DR   GO; GO:0070553; F:nicotinic acid receptor activity; ISS:UniProtKB.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.
DR   GO; GO:0001781; P:neutrophil apoptotic process; IDA:UniProtKB.
DR   GO; GO:0070165; P:positive regulation of adiponectin secretion; ISS:UniProtKB.
DR   GO; GO:0033031; P:positive regulation of neutrophil apoptotic process; IDA:UniProtKB.
//
ID   HCAR3_HUMAN             Reviewed;         387 AA.
AC   P49019; A8K4G5; B2R830; E9PI97; Q8NGE4;
DE   RecName: Full=Hydroxycarboxylic acid receptor 3;
DE   AltName: Full=G-protein coupled receptor 109B;
DE   AltName: Full=G-protein coupled receptor HM74;
DE   AltName: Full=G-protein coupled receptor HM74B;
DE   AltName: Full=Niacin receptor 2;
DE   AltName: Full=Nicotinic acid receptor 2;
GN   Name=HCAR3; Synonyms=GPR109B, HCA3, HM74B, NIACR2;
DR   GuidetoPHARMACOLOGY; 313; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   HCD2_HUMAN              Reviewed;         261 AA.
AC   Q99714; Q5H927; Q6IBS9; Q8TCV9; Q96HD5;
DE   RecName: Full=3-hydroxyacyl-CoA dehydrogenase type-2;
DE            EC=1.1.1.35;
DE   AltName: Full=17-beta-hydroxysteroid dehydrogenase 10;
DE            Short=17-beta-HSD 10;
DE            EC=1.1.1.51;
DE   AltName: Full=3-hydroxy-2-methylbutyryl-CoA dehydrogenase;
DE            EC=1.1.1.178;
DE   AltName: Full=3-hydroxyacyl-CoA dehydrogenase type II;
DE   AltName: Full=Endoplasmic reticulum-associated amyloid beta-peptide-binding protein;
DE   AltName: Full=Mitochondrial ribonuclease P protein 2;
DE            Short=Mitochondrial RNase P protein 2;
DE   AltName: Full=Short-chain type dehydrogenase/reductase XH98G2;
DE   AltName: Full=Type II HADH;
GN   Name=HSD17B10; Synonyms=ERAB, HADH2, MRPP2, SCHAD, XH98G2;
DR   GO; GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; EXP:Reactome.
DR   GO; GO:0008709; F:cholate 7-alpha-dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030283; F:testosterone dehydrogenase [NAD(P)] activity; IEA:UniProtKB-EC.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   HCDH_HUMAN              Reviewed;         314 AA.
AC   Q16836; J3KQ17; O00324; O00397; O00753; Q4W5B4;
DE   RecName: Full=Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial;
DE            Short=HCDH;
DE            EC=1.1.1.35;
DE   AltName: Full=Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase;
DE   AltName: Full=Short-chain 3-hydroxyacyl-CoA dehydrogenase;
DE   Flags: Precursor;
GN   Name=HADH; Synonyms=HAD, HADHSC, SCHAD;
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HCFC1_HUMAN             Reviewed;        2035 AA.
AC   P51610; Q6P4G5;
DE   RecName: Full=Host cell factor 1;
DE            Short=HCF;
DE            Short=HCF-1;
DE   AltName: Full=C1 factor;
DE   AltName: Full=CFF;
DE   AltName: Full=VCAF;
DE   AltName: Full=VP16 accessory protein;
DE   Contains:
DE     RecName: Full=HCF N-terminal chain 1;
DE   Contains:
DE     RecName: Full=HCF N-terminal chain 2;
DE   Contains:
DE     RecName: Full=HCF N-terminal chain 3;
DE   Contains:
DE     RecName: Full=HCF N-terminal chain 4;
DE   Contains:
DE     RecName: Full=HCF N-terminal chain 5;
DE   Contains:
DE     RecName: Full=HCF N-terminal chain 6;
DE   Contains:
DE     RecName: Full=HCF C-terminal chain 1;
DE   Contains:
DE     RecName: Full=HCF C-terminal chain 2;
DE   Contains:
DE     RecName: Full=HCF C-terminal chain 3;
DE   Contains:
DE     RecName: Full=HCF C-terminal chain 4;
DE   Contains:
DE     RecName: Full=HCF C-terminal chain 5;
DE   Contains:
DE     RecName: Full=HCF C-terminal chain 6;
GN   Name=HCFC1; Synonyms=HCF1, HFC1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0019046; P:release from viral latency; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   HCFC2_HUMAN             Reviewed;         792 AA.
AC   Q9Y5Z7; B2R8Q5;
DE   RecName: Full=Host cell factor 2;
DE            Short=HCF-2;
DE   AltName: Full=C2 factor;
GN   Name=HCFC2;
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:ProtInc.
//
ID   HCK_HUMAN               Reviewed;         526 AA.
AC   P08631; A8K1I1; B4DQB6; E1P5M2; Q29RX1; Q2VPE2; Q504R5; Q5T7K1;
AC   Q5T7K2; Q96CC0; Q9H5Y5; Q9NUA4; Q9UMJ5;
DE   RecName: Full=Tyrosine-protein kinase HCK;
DE            EC=2.7.10.2;
DE   AltName: Full=Hematopoietic cell kinase;
DE   AltName: Full=Hemopoietic cell kinase;
DE   AltName: Full=p59-HCK/p60-HCK;
DE   AltName: Full=p59Hck;
DE   AltName: Full=p61Hck;
GN   Name=HCK;
DR   GuidetoPHARMACOLOGY; 2032; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IMP:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002758; P:innate immune response-activating signal transduction; TAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0043299; P:leukocyte degranulation; TAS:UniProtKB.
DR   GO; GO:0002522; P:leukocyte migration involved in immune response; TAS:UniProtKB.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IMP:UniProtKB.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; TAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.
DR   GO; GO:0050764; P:regulation of phagocytosis; IMP:UniProtKB.
DR   GO; GO:0071801; P:regulation of podosome assembly; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045728; P:respiratory burst after phagocytosis; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   HCLS1_HUMAN             Reviewed;         486 AA.
AC   P14317; Q53Y93; Q6IBK9; Q9UDK0;
DE   RecName: Full=Hematopoietic lineage cell-specific protein;
DE   AltName: Full=Hematopoietic cell-specific LYN substrate 1;
DE   AltName: Full=LckBP1;
DE   AltName: Full=p75;
GN   Name=HCLS1; Synonyms=HS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:InterPro.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IMP:BHF-UCL.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:2000107; P:negative regulation of leukocyte apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IC:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0009725; P:response to hormone; ISS:UniProtKB.
//
ID   HCN1_HUMAN              Reviewed;         890 AA.
AC   O60741;
DE   RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1;
DE   AltName: Full=Brain cyclic nucleotide-gated channel 1;
DE            Short=BCNG-1;
GN   Name=HCN1; Synonyms=BCNG1;
DR   GuidetoPHARMACOLOGY; 400; -.
DR   GO; GO:0030552; F:cAMP binding; ISS:UniProtKB.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; ISS:UniProtKB.
DR   GO; GO:0005267; F:potassium channel activity; NAS:UniProtKB.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; ISS:UniProtKB.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IMP:UniProt.
DR   GO; GO:0045176; P:apical protein localization; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:UniProt.
DR   GO; GO:0046549; P:retinal cone cell development; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IMP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   HCN2_HUMAN              Reviewed;         889 AA.
AC   Q9UL51; O60742; O60743; O75267; Q9UBS2;
DE   RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2;
DE   AltName: Full=Brain cyclic nucleotide-gated channel 2;
DE            Short=BCNG-2;
GN   Name=HCN2; Synonyms=BCNG2;
DR   GuidetoPHARMACOLOGY; 401; -.
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IDA:UniProtKB.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IMP:UniProt.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0071321; P:cellular response to cGMP; IDA:UniProt.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:UniProt.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IMP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   HCN4_HUMAN              Reviewed;        1203 AA.
AC   Q9Y3Q4; Q9UMQ7;
DE   RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4;
GN   Name=HCN4;
DR   GuidetoPHARMACOLOGY; 403; -.
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005261; F:cation channel activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005222; F:intracellular cAMP activated cation channel activity; IDA:UniProtKB.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IMP:UniProt.
DR   GO; GO:0008015; P:blood circulation; NAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; TAS:ProtInc.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0071321; P:cellular response to cGMP; IDA:UniProt.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:UniProt.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IMP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   HCN3_HUMAN              Reviewed;         774 AA.
AC   Q9P1Z3; D3DV90; Q4VX12; Q8N6W6; Q9BWQ2;
DE   RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3;
GN   Name=HCN3; Synonyms=KIAA1535;
DR   GuidetoPHARMACOLOGY; 402; -.
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IMP:UniProt.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IMP:UniProt.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IMP:UniProt.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:UniProt.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IMP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   HCP5_HUMAN              Reviewed;         132 AA.
AC   Q6MZN7; Q04490;
DE   RecName: Full=HLA class I histocompatibility antigen protein P5;
DE   AltName: Full=HLA complex protein P5;
DE   AltName: Full=Protein P5-1;
GN   Name=HCP5;
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
//
ID   HCST_HUMAN              Reviewed;          93 AA.
AC   Q9UBK5; Q9UBS1; Q9Y3Y0;
DE   RecName: Full=Hematopoietic cell signal transducer;
DE   AltName: Full=DNAX-activation protein 10;
DE   AltName: Full=Membrane protein DAP10;
DE   AltName: Full=Transmembrane adapter protein KAP10;
DE   Flags: Precursor;
GN   Name=HCST; Synonyms=DAP10, KAP10, PIK3AP; ORFNames=UNQ587/PRO1157;
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HDA11_HUMAN             Reviewed;         347 AA.
AC   Q96DB2; B4DDK1; Q9H6I7; Q9H6X3; Q9NTC9;
DE   RecName: Full=Histone deacetylase 11;
DE            Short=HD11;
DE            EC=3.5.1.98;
GN   Name=HDAC11;
DR   GuidetoPHARMACOLOGY; 2615; -.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0008134; F:transcription factor binding; TAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; TAS:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDA10_HUMAN             Reviewed;         669 AA.
AC   Q969S8; Q08AP4; Q6STF9; Q96P77; Q96P78; Q9H028; Q9UGX1; Q9UGX2;
DE   RecName: Full=Histone deacetylase 10;
DE            Short=HD10;
DE            EC=3.5.1.98;
GN   Name=HDAC10;
DR   GuidetoPHARMACOLOGY; 2614; -.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; NAS:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDAC1_HUMAN             Reviewed;         482 AA.
AC   Q13547; Q92534;
DE   RecName: Full=Histone deacetylase 1;
DE            Short=HD1;
DE            EC=3.5.1.98;
GN   Name=HDAC1; Synonyms=RPD3L1;
DR   GuidetoPHARMACOLOGY; 2658; -.
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004407; F:histone deacetylase activity; IMP:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; TAS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IC:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.
DR   GO; GO:0016575; P:histone deacetylation; IMP:UniProtKB.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IMP:UniProtKB.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HDAC2_HUMAN             Reviewed;         488 AA.
AC   Q92769; B4DL58; E1P561; Q5SRI8; Q5SZ86; Q8NEH4;
DE   RecName: Full=Histone deacetylase 2;
DE            Short=HD2;
DE            EC=3.5.1.98;
GN   Name=HDAC2;
DR   GuidetoPHARMACOLOGY; 2616; -.
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IMP:BHF-UCL.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IC:BHF-UCL.
DR   GO; GO:0016358; P:dendrite development; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0009913; P:epidermal cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0061198; P:fungiform papilla formation; ISS:BHF-UCL.
DR   GO; GO:0060789; P:hair follicle placode formation; ISS:BHF-UCL.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0016575; P:histone deacetylation; IMP:BHF-UCL.
DR   GO; GO:0006344; P:maintenance of chromatin silencing; IMP:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045347; P:negative regulation of MHC class II biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IMP:BHF-UCL.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IC:BHF-UCL.
DR   GO; GO:0090311; P:regulation of protein deacetylation; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0060297; P:regulation of sarcomere organization; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDAC3_HUMAN             Reviewed;         428 AA.
AC   O15379; D3DQE1; O43268; Q9UEI5; Q9UEV0;
DE   RecName: Full=Histone deacetylase 3;
DE            Short=HD3;
DE            EC=3.5.1.98;
DE   AltName: Full=RPD3-2;
DE   AltName: Full=SMAP45;
GN   Name=HDAC3;
DR   GuidetoPHARMACOLOGY; 2617; -.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004407; F:histone deacetylase activity; IMP:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; TAS:UniProtKB.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDAC4_HUMAN             Reviewed;        1084 AA.
AC   P56524; Q9UND6;
DE   RecName: Full=Histone deacetylase 4;
DE            Short=HD4;
DE            EC=3.5.1.98;
GN   Name=HDAC4; Synonyms=KIAA0288;
DR   GuidetoPHARMACOLOGY; 2659; -.
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0030955; F:potassium ion binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; TAS:BHF-UCL.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0016575; P:histone deacetylation; IDA:BHF-UCL.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045820; P:negative regulation of glycolytic process; ISS:BHF-UCL.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; IMP:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0010882; P:regulation of cardiac muscle contraction by calcium ion signaling; IEA:Ensembl.
DR   GO; GO:0043393; P:regulation of protein binding; IMP:BHF-UCL.
DR   GO; GO:0048742; P:regulation of skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDAC5_HUMAN             Reviewed;        1122 AA.
AC   Q9UQL6; C9JFV9; O60340; O60528; Q96DY4;
DE   RecName: Full=Histone deacetylase 5;
DE            Short=HD5;
DE            EC=3.5.1.98;
DE   AltName: Full=Antigen NY-CO-9;
GN   Name=HDAC5; Synonyms=KIAA0600;
DR   GuidetoPHARMACOLOGY; 2660; -.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; NAS:BHF-UCL.
DR   GO; GO:0016568; P:chromatin modification; TAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:ProtInc.
DR   GO; GO:0006342; P:chromatin silencing; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0016575; P:histone deacetylation; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; IMP:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; IMP:BHF-UCL.
DR   GO; GO:0048742; P:regulation of skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDAC6_HUMAN             Reviewed;        1215 AA.
AC   Q9UBN7; O94975; Q6NT75; Q7L3E5; Q96CY0;
DE   RecName: Full=Histone deacetylase 6;
DE            Short=HD6;
DE            EC=3.5.1.98;
GN   Name=HDAC6; Synonyms=KIAA0901; ORFNames=JM21;
DR   GuidetoPHARMACOLOGY; 2618; -.
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0070840; F:dynein complex binding; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048156; F:tau protein binding; IDA:BHF-UCL.
DR   GO; GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070842; P:aggresome assembly; IMP:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IMP:BHF-UCL.
DR   GO; GO:0071218; P:cellular response to misfolded protein; IEA:Ensembl.
DR   GO; GO:0035967; P:cellular response to topologically incorrect protein; IMP:BHF-UCL.
DR   GO; GO:0016575; P:histone deacetylation; ISS:UniProtKB.
DR   GO; GO:0070846; P:Hsp90 deacetylation; IMP:BHF-UCL.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:BHF-UCL.
DR   GO; GO:0032418; P:lysosome localization; IMP:BHF-UCL.
DR   GO; GO:0016236; P:macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0010727; P:negative regulation of hydrogen peroxide metabolic process; IC:BHF-UCL.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Ensembl.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IC:BHF-UCL.
DR   GO; GO:0043242; P:negative regulation of protein complex disassembly; IMP:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; IMP:BHF-UCL.
DR   GO; GO:0070845; P:polyubiquitinated misfolded protein transport; IMP:BHF-UCL.
DR   GO; GO:0090035; P:positive regulation of chaperone-mediated protein complex assembly; IMP:BHF-UCL.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IMP:BHF-UCL.
DR   GO; GO:1901300; P:positive regulation of hydrogen peroxide-mediated programmed cell death; IDA:BHF-UCL.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IMP:BHF-UCL.
DR   GO; GO:0043241; P:protein complex disassembly; IEA:Ensembl.
DR   GO; GO:0006476; P:protein deacetylation; IMP:BHF-UCL.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0070201; P:regulation of establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0060632; P:regulation of microtubule-based movement; IC:BHF-UCL.
DR   GO; GO:0010469; P:regulation of receptor activity; IMP:BHF-UCL.
DR   GO; GO:0070848; P:response to growth factor; IMP:BHF-UCL.
DR   GO; GO:0051788; P:response to misfolded protein; IMP:BHF-UCL.
DR   GO; GO:0010033; P:response to organic substance; IMP:BHF-UCL.
DR   GO; GO:0009636; P:response to toxic substance; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0090042; P:tubulin deacetylation; ISS:UniProtKB.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:Ensembl.
//
ID   HDAC7_HUMAN             Reviewed;         952 AA.
AC   Q8WUI4; B3KY08; B4DWI0; B4E0Q5; Q6P1W9; Q6W9G7; Q7Z4K2; Q7Z5I1;
AC   Q96K01; Q9BR73; Q9H7L0; Q9NW41; Q9NWA9; Q9NYK9; Q9UFU7;
DE   RecName: Full=Histone deacetylase 7;
DE            Short=HD7;
DE            EC=3.5.1.98;
DE   AltName: Full=Histone deacetylase 7A;
DE            Short=HD7a;
GN   Name=HDAC7; Synonyms=HDAC7A;
DR   GuidetoPHARMACOLOGY; 2661; -.
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0007043; P:cell-cell junction assembly; IEA:Ensembl.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IDA:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   HDAC8_HUMAN             Reviewed;         377 AA.
AC   Q9BY41; A6ND12; A6ND61; A6NET3; A6NJR3; A8MQ62; B4DKN0; B4DV22;
AC   Q86VC8; Q9NP76; Q9NYH4;
DE   RecName: Full=Histone deacetylase 8;
DE            Short=HD8;
DE            EC=3.5.1.98;
GN   Name=HDAC8; Synonyms=HDACL1; ORFNames=CDA07;
DR   GuidetoPHARMACOLOGY; 2619; -.
DR   GO; GO:0004407; F:histone deacetylase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0008134; F:transcription factor binding; TAS:UniProtKB.
DR   GO; GO:0006333; P:chromatin assembly or disassembly; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0071922; P:regulation of cohesin localization to chromatin; IMP:UniProtKB.
DR   GO; GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDAC9_HUMAN             Reviewed;        1011 AA.
AC   Q9UKV0; A7E2F3; B7Z4I4; B7Z917; B7Z928; B7Z940; C9JS87; E7EX34;
AC   F8W9E0; O94845; O95028; Q2M2R6; Q86SL1; Q86US3;
DE   RecName: Full=Histone deacetylase 9;
DE            Short=HD9;
DE            EC=3.5.1.98;
DE   AltName: Full=Histone deacetylase 7B;
DE            Short=HD7;
DE            Short=HD7b;
DE   AltName: Full=Histone deacetylase-related protein;
DE   AltName: Full=MEF2-interacting transcription repressor MITR;
GN   Name=HDAC9; Synonyms=HDAC7, HDAC7B, HDRP, KIAA0744, MITR;
DR   GuidetoPHARMACOLOGY; 2620; -.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:UniProtKB-EC.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IEA:UniProtKB-EC.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IDA:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0016575; P:histone deacetylation; IDA:BHF-UCL.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; IDA:BHF-UCL.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0048742; P:regulation of skeletal muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0051153; P:regulation of striated muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HDBP1_HUMAN             Reviewed;         184 AA.
AC   Q8IV16; Q6P3T2; Q86W15;
DE   RecName: Full=Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1;
DE            Short=GPI-HBP1;
DE            Short=GPI-anchored HDL-binding protein 1;
DE   AltName: Full=High density lipoprotein-binding protein 1;
DE   Flags: Precursor;
GN   Name=GPIHBP1; Synonyms=HBP1;
DR   GO; GO:0035478; F:chylomicron binding; IDA:BHF-UCL.
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0035473; F:lipase binding; IPI:BHF-UCL.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0071813; F:lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:Ensembl.
DR   GO; GO:0090321; P:positive regulation of chylomicron remnant clearance; ISS:BHF-UCL.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IMP:BHF-UCL.
DR   GO; GO:0017038; P:protein import; ISS:BHF-UCL.
DR   GO; GO:0034394; P:protein localization to cell surface; ISS:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; ISS:BHF-UCL.
DR   GO; GO:0071806; P:protein transmembrane transport; ISS:GOC.
DR   GO; GO:0071503; P:response to heparin; IMP:BHF-UCL.
DR   GO; GO:0045056; P:transcytosis; ISS:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:BHF-UCL.
//
ID   HDC_HUMAN               Reviewed;         543 AA.
AC   Q9UBI9;
DE   RecName: Full=Headcase protein homolog;
DE            Short=hHDC;
GN   Name=HECA; Synonyms=HDC;
DR   GO; GO:0030323; P:respiratory tube development; NAS:UniProtKB.
//
ID   HDDC2_HUMAN             Reviewed;         204 AA.
AC   Q7Z4H3; Q5TDQ4; Q6NZ49; Q9BTT2; Q9BV31; Q9Y3D1;
DE   RecName: Full=HD domain-containing protein 2;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 2;
DE            Short=HCV NS5A-transactivated protein 2;
GN   Name=HDDC2; Synonyms=C6orf74, NS5ATP2; ORFNames=CGI-130;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   HDGF_HUMAN              Reviewed;         240 AA.
AC   P51858; B3KU21; D3DVC9; Q5SZ07; Q5SZ08; Q5SZ09;
DE   RecName: Full=Hepatoma-derived growth factor;
DE            Short=HDGF;
DE   AltName: Full=High mobility group protein 1-like 2;
DE            Short=HMG-1L2;
GN   Name=HDGF; Synonyms=HMG1L2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0001222; F:transcription corepressor binding; IPI:BHF-UCL.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   HDGL1_HUMAN             Reviewed;         251 AA.
AC   Q5TGJ6; Q96MJ6;
DE   RecName: Full=Hepatoma-derived growth factor-like protein 1;
DE   AltName: Full=PWWP domain-containing protein 1;
GN   Name=HDGFL1; Synonyms=PWWP1;
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
//
ID   HDGR2_HUMAN             Reviewed;         671 AA.
AC   Q7Z4V5; I3L080; Q96GI5; Q9BW08;
DE   RecName: Full=Hepatoma-derived growth factor-related protein 2;
DE            Short=HRP-2;
DE   AltName: Full=Hepatoma-derived growth factor 2;
DE            Short=HDGF-2;
GN   Name=HDGFRP2; Synonyms=HDGF2; ORFNames=UNQ785/PRO1604;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   HDGR3_HUMAN             Reviewed;         203 AA.
AC   Q9Y3E1;
DE   RecName: Full=Hepatoma-derived growth factor-related protein 3;
DE            Short=HRP-3;
DE   AltName: Full=Hepatoma-derived growth factor 2;
DE            Short=HDGF-2;
GN   Name=HDGFRP3; Synonyms=HDGF2; ORFNames=CGI-142;
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
//
ID   HDHD2_HUMAN             Reviewed;         259 AA.
AC   Q9H0R4; A8K7T3; Q96NV4;
DE   RecName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 2;
GN   Name=HDHD2;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   HDHD1_HUMAN             Reviewed;         228 AA.
AC   Q08623; B2R7X6; B4DV93; B7Z6Q3; E9PAV8; F5GWZ2; Q53F84; Q96EB8;
DE   RecName: Full=Pseudouridine-5'-monophosphatase;
DE            Short=5'-PsiMPase;
DE            EC=3.1.3.n6;
DE   AltName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 1;
DE   AltName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 1A;
DE   AltName: Full=Protein GS1;
GN   Name=HDHD1; Synonyms=DXF68S1E, FAM16AX, GS1, HDHD1A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
//
ID   HDHD3_HUMAN             Reviewed;         251 AA.
AC   Q9BSH5; B2RD47;
DE   RecName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 3;
GN   Name=HDHD3; Synonyms=C9orf158;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   HDX_HUMAN               Reviewed;         690 AA.
AC   Q7Z353; A8K1Y5; B7ZL18; Q5JZB4; Q96NK7;
DE   RecName: Full=Highly divergent homeobox;
GN   Name=HDX; Synonyms=CXorf43;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   HD_HUMAN                Reviewed;        3142 AA.
AC   P42858; Q9UQB7;
DE   RecName: Full=Huntingtin;
DE   AltName: Full=Huntington disease protein;
DE            Short=HD protein;
GN   Name=HTT; Synonyms=HD, IT15;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0050809; F:diazepam binding; IEA:Ensembl.
DR   GO; GO:0034452; F:dynactin binding; IPI:UniProtKB.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IBA:RefGenome.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0000052; P:citrulline metabolic process; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:Ensembl.
DR   GO; GO:0016197; P:endosomal transport; IEA:Ensembl.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0051938; P:L-glutamate import; IEA:Ensembl.
DR   GO; GO:0019244; P:lactate biosynthetic process from pyruvate; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0021990; P:neural plate formation; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0021988; P:olfactory lobe development; IEA:Ensembl.
DR   GO; GO:0048513; P:organ development; IBA:RefGenome.
DR   GO; GO:0048341; P:paraxial mesoderm formation; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0019805; P:quinolinate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:0046825; P:regulation of protein export from nucleus; IMP:UniProtKB.
DR   GO; GO:0034047; P:regulation of protein phosphatase type 2A activity; IMP:dictyBase.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
DR   GO; GO:0000050; P:urea cycle; IEA:Ensembl.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IMP:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   HEAS1_HUMAN             Reviewed;         139 AA.
AC   Q9H8Q6;
DE   RecName: Full=Putative uncharacterized protein encoded by HEXA-AS1;
DE   AltName: Full=HEXA antisense RNA 1;
DE   AltName: Full=HEXA antisense gene protein 1;
GN   Name=HEXA-AS1; Synonyms=C15orf34;
//
ID   HEAT1_HUMAN             Reviewed;        2144 AA.
AC   Q9H583; Q5T3Q8; Q6P197; Q9NW23;
DE   RecName: Full=HEAT repeat-containing protein 1;
DE   AltName: Full=Protein BAP28;
DE   Contains:
DE     RecName: Full=HEAT repeat-containing protein 1, N-terminally processed;
GN   Name=HEATR1; Synonyms=BAP28;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   HEAT2_HUMAN             Reviewed;         855 AA.
AC   Q86Y56; Q69YL1; Q96FI9; Q9NX75;
DE   RecName: Full=HEAT repeat-containing protein 2;
GN   Name=HEATR2;
//
ID   HEAT3_HUMAN             Reviewed;         680 AA.
AC   Q7Z4Q2; A8K1N4; Q8N525; Q8WV56; Q96CC9; Q9NWN7;
DE   RecName: Full=HEAT repeat-containing protein 3;
GN   Name=HEATR3;
//
ID   HEAT4_HUMAN             Reviewed;        1026 AA.
AC   Q86WZ0; B7Z7V9; E9KL41;
DE   RecName: Full=HEAT repeat-containing protein 4;
GN   Name=HEATR4;
//
ID   HEAT6_HUMAN             Reviewed;        1181 AA.
AC   Q6AI08; B3KXP3; Q6MZX1; Q6MZY2; Q8TDM9; Q9H6B3; Q9H6M7;
DE   RecName: Full=HEAT repeat-containing protein 6;
DE   AltName: Full=Amplified in breast cancer protein 1;
GN   Name=HEATR6; Synonyms=ABC1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   HEBP1_HUMAN             Reviewed;         189 AA.
AC   Q9NRV9; A8K1G2; Q9Y5Z5;
DE   RecName: Full=Heme-binding protein 1;
DE   AltName: Full=p22HBP;
GN   Name=HEBP1; Synonyms=HBP;
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
//
ID   HEBP2_HUMAN             Reviewed;         205 AA.
AC   Q9Y5Z4; Q96P57;
DE   RecName: Full=Heme-binding protein 2;
DE   AltName: Full=Placental protein 23;
DE            Short=PP23;
DE   AltName: Full=Protein SOUL;
GN   Name=HEBP2; Synonyms=C6orf34, SOUL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0010917; P:negative regulation of mitochondrial membrane potential; IMP:UniProt.
DR   GO; GO:0035794; P:positive regulation of mitochondrial membrane permeability; IMP:UniProt.
DR   GO; GO:0010940; P:positive regulation of necrotic cell death; IMP:UniProt.
//
ID   HECA2_HUMAN             Reviewed;         462 AA.
AC   A8MVW5; B3KTT4; B4DPJ1; B9EG93; E9PDV5; Q6UXI0;
DE   RecName: Full=HEPACAM family member 2;
DE   AltName: Full=Mitotic kinetics regulator;
DE   Flags: Precursor;
GN   Name=HEPACAM2; Synonyms=MIKI; ORFNames=UNQ305/PRO346;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   HECAM_HUMAN             Reviewed;         416 AA.
AC   Q14CZ8; Q67IP8; Q6ZWL4; Q8N7I3; Q8ND35;
DE   RecName: Full=Hepatocyte cell adhesion molecule;
DE            Short=Protein hepaCAM;
DE   Flags: Precursor;
GN   Name=HEPACAM;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   HECD1_HUMAN             Reviewed;        2610 AA.
AC   Q9ULT8; D3DS86; Q6P445; Q86VJ1; Q96F34; Q9UFZ7;
DE   RecName: Full=E3 ubiquitin-protein ligase HECTD1;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ligase for inhibin receptor;
DE   AltName: Full=EULIR;
DE   AltName: Full=HECT domain-containing protein 1;
GN   Name=HECTD1; Synonyms=KIAA1131;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HECD2_HUMAN             Reviewed;         776 AA.
AC   Q5U5R9; Q5VZ97; Q5VZ98; Q5VZ99; Q8N1X7; Q8TCP5;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase HECTD2;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain-containing protein 2;
GN   Name=HECTD2;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HECD3_HUMAN             Reviewed;         861 AA.
AC   Q5T447; B3KPV7; B3KRH4; Q5T448; Q9H783;
DE   RecName: Full=E3 ubiquitin-protein ligase HECTD3;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain-containing protein 3;
GN   Name=HECTD3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HECD4_HUMAN             Reviewed;        3996 AA.
AC   Q9Y4D8; L8B0P6; Q3MJD5; Q6P0A0; Q7L530; Q8NB70; Q8WU73; Q96NT9;
AC   Q9NZS4; Q9UFT6;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase HECTD4;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain-containing protein 4;
GN   Name=HECTD4; Synonyms=C12orf51, KIAA0614;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProt.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:UniProt.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HECW1_HUMAN             Reviewed;        1606 AA.
AC   Q76N89; A7E2X0; A8MYS3; B4DH42; O15036; Q9HCC7;
DE   RecName: Full=E3 ubiquitin-protein ligase HECW1;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT, C2 and WW domain-containing protein 1;
DE   AltName: Full=NEDD4-like E3 ubiquitin-protein ligase 1;
DE            Short=hNEDL1;
GN   Name=HECW1; Synonyms=KIAA0322, NEDL1;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HECW2_HUMAN             Reviewed;        1572 AA.
AC   Q9P2P5; B8ZZB4; Q17RT5; Q68DF8; Q9NPS9;
DE   RecName: Full=E3 ubiquitin-protein ligase HECW2;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT, C2 and WW domain-containing protein 2;
DE   AltName: Full=NEDD4-like E3 ubiquitin-protein ligase 2;
GN   Name=HECW2; Synonyms=KIAA1301, NEDL2;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HEG1_HUMAN              Reviewed;        1381 AA.
AC   Q9ULI3; Q6NX66; Q8NC40; Q9BSV0;
DE   RecName: Full=Protein HEG homolog 1;
DE   Flags: Precursor;
GN   Name=HEG1; Synonyms=KIAA1237;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003209; P:cardiac atrium morphogenesis; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; IEA:Ensembl.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0003017; P:lymph circulation; IEA:Ensembl.
DR   GO; GO:0001945; P:lymph vessel development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0050878; P:regulation of body fluid levels; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0048845; P:venous blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   HELB_HUMAN              Reviewed;        1087 AA.
AC   Q8NG08; A8K4C9; Q4G0T2; Q9H7L5;
DE   RecName: Full=DNA helicase B;
DE            Short=hDHB;
DE            EC=3.6.4.12;
GN   Name=HELB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0017116; F:single-stranded DNA-dependent ATP-dependent DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IDA:UniProtKB.
//
ID   HELLS_HUMAN             Reviewed;         838 AA.
AC   Q9NRZ9; B2RB41; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79;
AC   Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5;
DE   RecName: Full=Lymphoid-specific helicase;
DE            EC=3.6.4.-;
DE   AltName: Full=Proliferation-associated SNF2-like protein;
DE   AltName: Full=SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6;
GN   Name=HELLS; Synonyms=PASG, SMARCA6; ORFNames=Nbla10143;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031508; P:centromeric heterochromatin assembly; ISS:UniProtKB.
DR   GO; GO:0046651; P:lymphocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0010216; P:maintenance of DNA methylation; ISS:UniProtKB.
DR   GO; GO:0006346; P:methylation-dependent chromatin silencing; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001655; P:urogenital system development; IEA:Ensembl.
//
ID   HELQ_HUMAN              Reviewed;        1101 AA.
AC   Q8TDG4; Q05DF9; Q502W9; Q659B8; Q6ZQX4; Q6ZTS4; Q96EX7;
DE   RecName: Full=Helicase POLQ-like;
DE            EC=3.6.4.12;
DE   AltName: Full=Mus308-like helicase;
DE   AltName: Full=POLQ-like helicase;
GN   Name=HELQ; Synonyms=HEL308;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProt.
//
ID   HELT_HUMAN              Reviewed;         327 AA.
AC   A6NFD8; B2RTS5; B7ZMI8;
DE   RecName: Full=Hairy and enhancer of split-related protein HELT;
DE   AltName: Full=HES/HEY-like transcription factor;
GN   Name=HELT;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0021858; P:GABAergic neuron differentiation in basal ganglia; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HELZ2_HUMAN             Reviewed;        2649 AA.
AC   Q9BYK8; Q3C2G2; Q4VXQ1; Q8TEF3; Q96ND3; Q9C094;
DE   RecName: Full=Helicase with zinc finger domain 2;
DE   AltName: Full=ATP-dependent helicase PRIC285;
DE   AltName: Full=Helicase with zinc finger 2, transcriptional coactivator;
DE   AltName: Full=PPAR-alpha-interacting complex protein 285;
DE   AltName: Full=PPAR-gamma DNA-binding domain-interacting protein 1;
DE            Short=PDIP1;
DE            Short=PPAR-gamma DBD-interacting protein 1;
DE   AltName: Full=Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein;
DE            EC=3.6.4.-;
GN   Name=HELZ2; Synonyms=KIAA1769, PRIC285;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HELZ_HUMAN              Reviewed;        1942 AA.
AC   P42694; I6L9H4;
DE   RecName: Full=Probable helicase with zinc finger domain;
DE            EC=3.6.4.-;
DE   AltName: Full=Down-regulated in human cancers protein;
GN   Name=HELZ; Synonyms=DRHC, KIAA0054;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   HEM0_HUMAN              Reviewed;         587 AA.
AC   P22557; A8K3F0; A8K6C4; Q13735; Q5JZF5; Q8N6H3;
DE   RecName: Full=5-aminolevulinate synthase, erythroid-specific, mitochondrial;
DE            Short=ALAS-E;
DE            EC=2.3.1.37;
DE   AltName: Full=5-aminolevulinic acid synthase 2;
DE   AltName: Full=Delta-ALA synthase 2;
DE   AltName: Full=Delta-aminolevulinate synthase 2;
DE   Flags: Precursor;
GN   Name=ALAS2; Synonyms=ALASE, ASB;
DR   GO; GO:0003870; F:5-aminolevulinate synthase activity; IDA:UniProtKB.
DR   GO; GO:0050662; F:coenzyme binding; ISS:UniProtKB.
DR   GO; GO:0016594; F:glycine binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0032364; P:oxygen homeostasis; NAS:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HEM1_HUMAN              Reviewed;         640 AA.
AC   P13196;
DE   RecName: Full=5-aminolevulinate synthase, nonspecific, mitochondrial;
DE            Short=ALAS-H;
DE            EC=2.3.1.37;
DE   AltName: Full=5-aminolevulinic acid synthase 1;
DE   AltName: Full=Delta-ALA synthase 1;
DE   AltName: Full=Delta-aminolevulinate synthase 1;
DE   Flags: Precursor;
GN   Name=ALAS1; Synonyms=ALAS3, ALASH; ORFNames=OK/SW-cl.121;
DR   GO; GO:0003870; F:5-aminolevulinate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:Reactome.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HEM2_HUMAN              Reviewed;         330 AA.
AC   P13716; A8K375; B2R6F2; Q16870; Q16871; Q9BVQ9;
DE   RecName: Full=Delta-aminolevulinic acid dehydratase;
DE            Short=ALADH;
DE            EC=4.2.1.24;
DE   AltName: Full=Porphobilinogen synthase;
GN   Name=ALAD;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0032791; F:lead ion binding; IDA:UniProtKB.
DR   GO; GO:0004655; F:porphobilinogen synthase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0006783; P:heme biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HEM3_HUMAN              Reviewed;         361 AA.
AC   P08397; A8K2L0; G3V1P4; G5EA58; P08396; Q16012;
DE   RecName: Full=Porphobilinogen deaminase;
DE            Short=PBG-D;
DE            EC=2.5.1.61;
DE   AltName: Full=Hydroxymethylbilane synthase;
DE            Short=HMBS;
DE   AltName: Full=Pre-uroporphyrinogen synthase;
GN   Name=HMBS; Synonyms=PBGD, UPS;
DR   GO; GO:0004418; F:hydroxymethylbilane synthase activity; IDA:UniProtKB.
DR   GO; GO:0006783; P:heme biosynthetic process; IC:UniProtKB.
DR   GO; GO:0018160; P:peptidyl-pyrromethane cofactor linkage; IEA:InterPro.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HEM4_HUMAN              Reviewed;         265 AA.
AC   P10746; B2RC13; D3DRF7; Q9H2T1;
DE   RecName: Full=Uroporphyrinogen-III synthase;
DE            Short=UROIIIS;
DE            Short=UROS;
DE            EC=4.2.1.75;
DE   AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing];
DE   AltName: Full=Uroporphyrinogen-III cosynthase;
GN   Name=UROS;
DR   GO; GO:0048037; F:cofactor binding; IEA:Ensembl.
DR   GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IDA:UniProtKB.
DR   GO; GO:0071418; P:cellular response to amine stimulus; IEA:Ensembl.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0006783; P:heme biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IDA:UniProtKB.
//
ID   HEM6_HUMAN              Reviewed;         454 AA.
AC   P36551; A8K275; Q14060; Q53F08; Q8IZ45; Q96AF3;
DE   RecName: Full=Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial;
DE            Short=COX;
DE            Short=Coprogen oxidase;
DE            Short=Coproporphyrinogenase;
DE            EC=1.3.3.3;
DE   Flags: Precursor;
GN   Name=CPOX; Synonyms=CPO, CPX;
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; TAS:Reactome.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:Ensembl.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:Reactome.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0017085; P:response to insecticide; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HEMGN_HUMAN             Reviewed;         484 AA.
AC   Q9BXL5; Q6XAR3; Q86XY5; Q9NPC0;
DE   RecName: Full=Hemogen;
DE   AltName: Full=Erythroid differentiation-associated gene protein;
DE            Short=EDAG-1;
DE   AltName: Full=Hemopoietic gene protein;
DE   AltName: Full=Negative differentiation regulator protein;
GN   Name=HEMGN; Synonyms=EDAG, NDR; ORFNames=PRO1037, PRO1620;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IEA:Ensembl.
//
ID   HEMH_HUMAN              Reviewed;         423 AA.
AC   P22830; A8KA72; Q8IXN1; Q8NAN0;
DE   RecName: Full=Ferrochelatase, mitochondrial;
DE            EC=4.99.1.1;
DE   AltName: Full=Heme synthase;
DE   AltName: Full=Protoheme ferro-lyase;
DE   Flags: Precursor;
GN   Name=FECH;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004325; F:ferrochelatase activity; IDA:BHF-UCL.
DR   GO; GO:0008198; F:ferrous iron binding; TAS:ProtInc.
DR   GO; GO:0020037; F:heme binding; IEA:Ensembl.
DR   GO; GO:0030350; F:iron-responsive element binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0009589; P:detection of UV; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:Reactome.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0046501; P:protoporphyrinogen IX metabolic process; IDA:BHF-UCL.
DR   GO; GO:0010999; P:regulation of eIF2 alpha phosphorylation by heme; IEA:Ensembl.
DR   GO; GO:0046984; P:regulation of hemoglobin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0017085; P:response to insecticide; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; TAS:ProtInc.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
DR   GO; GO:0070541; P:response to platinum ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; IEA:Ensembl.
//
ID   HEMK1_HUMAN             Reviewed;         338 AA.
AC   Q9Y5R4;
DE   RecName: Full=HemK methyltransferase family member 1;
DE            EC=2.1.1.-;
DE   AltName: Full=M.HsaHemKP;
GN   Name=HEMK1; Synonyms=HEMK;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
//
ID   HEMK2_HUMAN             Reviewed;         214 AA.
AC   Q9Y5N5; Q96F73;
DE   RecName: Full=HemK methyltransferase family member 2;
DE            EC=2.1.1.-;
DE   AltName: Full=M.HsaHemK2P;
DE   AltName: Full=N(6)-adenine-specific DNA methyltransferase 1;
GN   Name=N6AMT1; Synonyms=C21orf127, HEMK2; ORFNames=PRED28;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008276; F:protein methyltransferase activity; IDA:MGI.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:MGI.
DR   GO; GO:0006479; P:protein methylation; IDA:GOC.
//
ID   HEMO_HUMAN              Reviewed;         462 AA.
AC   P02790; B2R957;
DE   RecName: Full=Hemopexin;
DE   AltName: Full=Beta-1B-glycoprotein;
DE   Flags: Precursor;
GN   Name=HPX;
DR   GO; GO:0015232; F:heme transporter activity; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:ProtInc.
DR   GO; GO:0042168; P:heme metabolic process; IEA:Ensembl.
DR   GO; GO:0015886; P:heme transport; TAS:ProtInc.
DR   GO; GO:0020027; P:hemoglobin metabolic process; IEA:Ensembl.
DR   GO; GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IEA:Ensembl.
DR   GO; GO:0060335; P:positive regulation of interferon-gamma-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HEN1_HUMAN              Reviewed;         133 AA.
AC   Q02575;
DE   RecName: Full=Helix-loop-helix protein 1;
DE            Short=HEN-1;
DE   AltName: Full=Class A basic helix-loop-helix protein 35;
DE            Short=bHLHa35;
DE   AltName: Full=Nescient helix loop helix 1;
DE            Short=NSCL-1;
GN   Name=NHLH1; Synonyms=BHLHA35, HEN1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HEN2_HUMAN              Reviewed;         135 AA.
AC   Q02577; Q5T1P6;
DE   RecName: Full=Helix-loop-helix protein 2;
DE            Short=HEN-2;
DE   AltName: Full=Class A basic helix-loop-helix protein 34;
DE            Short=bHLHa34;
DE   AltName: Full=Nescient helix loop helix 2;
DE            Short=NSCL-2;
GN   Name=NHLH2; Synonyms=BHLHA34, HEN2, KIAA0490;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007617; P:mating behavior; IEA:Ensembl.
DR   GO; GO:0042698; P:ovulation cycle; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HENMT_HUMAN             Reviewed;         393 AA.
AC   Q5T8I9; A8MRR6; B1AM16; B1AM17; Q96EJ7; Q96NN0;
DE   RecName: Full=Small RNA 2'-O-methyltransferase;
DE            EC=2.1.1.n8;
DE   AltName: Full=HEN1 methyltransferase homolog 1;
GN   Name=HENMT1; Synonyms=C1orf59;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008171; F:O-methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008173; F:RNA methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0001510; P:RNA methylation; ISS:UniProtKB.
//
ID   HEP2_HUMAN              Reviewed;         499 AA.
AC   P05546; B2RAI1; D3DX34; Q6IBZ5;
DE   RecName: Full=Heparin cofactor 2;
DE   AltName: Full=Heparin cofactor II;
DE            Short=HC-II;
DE   AltName: Full=Protease inhibitor leuserpin-2;
DE            Short=HLS2;
DE   AltName: Full=Serpin D1;
DE   Flags: Precursor;
GN   Name=SERPIND1; Synonyms=HCF2;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   HEPC_HUMAN              Reviewed;          84 AA.
AC   P81172; Q1HE14; Q9BY68;
DE   RecName: Full=Hepcidin;
DE   AltName: Full=Liver-expressed antimicrobial peptide 1;
DE            Short=LEAP-1;
DE   AltName: Full=Putative liver tumor regressor;
DE            Short=PLTR;
DE   Contains:
DE     RecName: Full=Hepcidin-25;
DE              Short=Hepc25;
DE   Contains:
DE     RecName: Full=Hepcidin-20;
DE              Short=Hepc20;
DE   Flags: Precursor;
GN   Name=HAMP; Synonyms=HEPC, LEAP1; ORFNames=UNQ487/PRO1003;
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   HEPH_HUMAN              Reviewed;        1158 AA.
AC   Q9BQS7; B1AJX8; D3DVT7; E9PHN8; O75180; Q6UW45; Q9C058;
DE   RecName: Full=Hephaestin;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=HEPH; Synonyms=KIAA0698; ORFNames=UNQ2562/PRO6242;
DR   GO; GO:0005507; F:copper ion binding; IMP:UniProt.
DR   GO; GO:0008198; F:ferrous iron binding; IMP:UniProt.
DR   GO; GO:0004322; F:ferroxidase activity; IMP:UniProt.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IMP:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   HEPN1_HUMAN             Reviewed;          88 AA.
AC   Q6WQI6;
DE   RecName: Full=Putative cancer susceptibility gene HEPN1 protein;
GN   Name=HEPN1;
//
ID   HEPS_HUMAN              Reviewed;         417 AA.
AC   P05981; B2RDS4;
DE   RecName: Full=Serine protease hepsin;
DE            EC=3.4.21.106;
DE   AltName: Full=Transmembrane protease serine 1;
DE   Contains:
DE     RecName: Full=Serine protease hepsin non-catalytic chain;
DE   Contains:
DE     RecName: Full=Serine protease hepsin catalytic chain;
GN   Name=HPN; Synonyms=TMPRSS1;
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; ISS:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0070008; F:serine-type exopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0034769; P:basement membrane disassembly; IDA:UniProtKB.
DR   GO; GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; ISS:UniProtKB.
DR   GO; GO:0060429; P:epithelium development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0097195; P:pilomotor reflex; ISS:UniProtKB.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:2000347; P:positive regulation of hepatocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0010756; P:positive regulation of plasminogen activation; IDA:UniProtKB.
DR   GO; GO:2000611; P:positive regulation of thyroid hormone generation; ISS:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0097066; P:response to thyroid hormone; ISS:UniProtKB.
//
ID   HERC1_HUMAN             Reviewed;        4861 AA.
AC   Q15751; Q8IW65;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase HERC1;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain and RCC1-like domain-containing protein 1;
DE   AltName: Full=p532;
DE   AltName: Full=p619;
GN   Name=HERC1;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0010507; P:negative regulation of autophagy; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   HERC2_HUMAN             Reviewed;        4834 AA.
AC   O95714; Q86SV7; Q86SV8; Q86SV9; Q86YY3; Q86YY4; Q86YY5; Q86YY6;
AC   Q86YY7; Q86YY8; Q86YY9; Q86YZ0; Q86YZ1;
DE   RecName: Full=E3 ubiquitin-protein ligase HERC2;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain and RCC1-like domain-containing protein 2;
GN   Name=HERC2;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032183; F:SUMO binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0043087; P:regulation of GTPase activity; NAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   HERC3_HUMAN             Reviewed;        1050 AA.
AC   Q15034; A8K1S5;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase HERC3;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain and RCC1-like domain-containing protein 3;
GN   Name=HERC3; Synonyms=KIAA0032;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HERC4_HUMAN             Reviewed;        1057 AA.
AC   Q5GLZ8; Q5GC98; Q5GC99; Q5GCA0; Q8IXP9; Q9HCH9;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase HERC4;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain and RCC1-like domain-containing protein 4;
GN   Name=HERC4; Synonyms=KIAA1593;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   HERC5_HUMAN             Reviewed;        1024 AA.
AC   Q9UII4; B2RTQ1; Q69G20;
DE   RecName: Full=E3 ISG15--protein ligase HERC5;
DE            EC=6.3.2.-;
DE   AltName: Full=Cyclin-E-binding protein 1;
DE   AltName: Full=HECT domain and RCC1-like domain-containing protein 5;
GN   Name=HERC5; Synonyms=CEB1, CEBP1;
DR   GO; GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.
//
ID   HERC6_HUMAN             Reviewed;        1022 AA.
AC   Q8IVU3; B4DIY5; Q5GC90; Q5GRH3; Q5HYM6; Q5JPB6; Q6PIF4; Q8NAN3;
AC   Q9NWS4;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase HERC6;
DE            EC=6.3.2.-;
DE   AltName: Full=HECT domain and RCC1-like domain-containing protein 6;
GN   Name=HERC6;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HERP2_HUMAN             Reviewed;         406 AA.
AC   Q9BSE4; A4D1Y8; Q9H6F9;
DE   RecName: Full=Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein;
GN   Name=HERPUD2;
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   HERP1_HUMAN             Reviewed;         391 AA.
AC   Q15011; E9PGD1; O60644; Q6IAN8; Q96D92;
DE   RecName: Full=Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein;
DE   AltName: Full=Methyl methanesulfonate (MMF)-inducible fragment protein 1;
GN   Name=HERPUD1; Synonyms=HERP, KIAA0025, MIF1;
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; IEP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   HES2_HUMAN              Reviewed;         173 AA.
AC   Q9Y543; A2RTZ9; Q96EN4; Q9Y542;
DE   RecName: Full=Transcription factor HES-2;
DE   AltName: Full=Class B basic helix-loop-helix protein 40;
DE            Short=bHLHb40;
DE   AltName: Full=Hairy and enhancer of split 2;
GN   Name=HES2; Synonyms=BHLHB40;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HES1_HUMAN              Reviewed;         280 AA.
AC   Q14469; Q6FHB2;
DE   RecName: Full=Transcription factor HES-1;
DE   AltName: Full=Class B basic helix-loop-helix protein 39;
DE            Short=bHLHb39;
DE   AltName: Full=Hairy and enhancer of split 1;
DE   AltName: Full=Hairy homolog;
DE   AltName: Full=Hairy-like protein;
DE            Short=hHL;
GN   Name=HES1; Synonyms=BHLHB39, HL, HRY;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0071820; F:N-box binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0021984; P:adenohypophysis development; IEA:Ensembl.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042668; P:auditory receptor cell fate determination; IEA:Ensembl.
DR   GO; GO:0061309; P:cardiac neural crest cell development involved in outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0072049; P:comma-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0061009; P:common bile duct development; IEA:Ensembl.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0021861; P:forebrain radial glial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072012; P:glomerulus vasculature development; IEA:Ensembl.
DR   GO; GO:0021575; P:hindbrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0046331; P:lateral inhibition; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0072282; P:metanephric nephron tubule morphogenesis; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0021555; P:midbrain-hindbrain boundary morphogenesis; IEA:Ensembl.
DR   GO; GO:0045608; P:negative regulation of auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:2000978; P:negative regulation of forebrain neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:2000227; P:negative regulation of pancreatic A cell differentiation; IEA:Ensembl.
DR   GO; GO:2000974; P:negative regulation of pro-B cell differentiation; IMP:UniProtKB.
DR   GO; GO:2000737; P:negative regulation of stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0061106; P:negative regulation of stomach neuroendocrine cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0021557; P:oculomotor nerve development; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.
DR   GO; GO:0045977; P:positive regulation of mitotic cell cycle, embryonic; ISS:BHF-UCL.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; ISS:UniProtKB.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0003266; P:regulation of secondary heart field cardioblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0060164; P:regulation of timing of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0072141; P:renal interstitial cell development; IEA:Ensembl.
DR   GO; GO:0072050; P:S-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0007262; P:STAT protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; ISS:BHF-UCL.
DR   GO; GO:0021558; P:trochlear nerve development; IEA:Ensembl.
DR   GO; GO:0060675; P:ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0097084; P:vascular smooth muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0003281; P:ventricular septum development; ISS:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   HES3_HUMAN              Reviewed;         186 AA.
AC   Q5TGS1; Q5TGS0;
DE   RecName: Full=Transcription factor HES-3;
DE   AltName: Full=Class B basic helix-loop-helix protein 43;
DE            Short=bHLHb43;
DE   AltName: Full=Hairy and enhancer of split 3;
GN   Name=HES3; Synonyms=BHLHB43;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0021575; P:hindbrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0021555; P:midbrain-hindbrain boundary morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021557; P:oculomotor nerve development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060164; P:regulation of timing of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021558; P:trochlear nerve development; IEA:Ensembl.
//
ID   HES4_HUMAN              Reviewed;         221 AA.
AC   Q9HCC6; Q5SVA5;
DE   RecName: Full=Transcription factor HES-4;
DE            Short=hHES4;
DE   AltName: Full=Class B basic helix-loop-helix protein 42;
DE            Short=bHLHb42;
DE   AltName: Full=Hairy and enhancer of split 4;
DE   AltName: Full=bHLH factor Hes4;
GN   Name=HES4; Synonyms=BHLHB42;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HES5_HUMAN              Reviewed;         166 AA.
AC   Q5TA89; B9DI85;
DE   RecName: Full=Transcription factor HES-5;
DE   AltName: Full=Class B basic helix-loop-helix protein 38;
DE            Short=bHLHb38;
DE   AltName: Full=Hairy and enhancer of split 5;
GN   Name=HES5; Synonyms=BHLHB38;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0048708; P:astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042668; P:auditory receptor cell fate determination; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; ISS:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0048469; P:cell maturation; ISS:UniProtKB.
DR   GO; GO:0022010; P:central nervous system myelination; ISS:UniProtKB.
DR   GO; GO:0072049; P:comma-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0021861; P:forebrain radial glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0021781; P:glial cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0072282; P:metanephric nephron tubule morphogenesis; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:2000978; P:negative regulation of forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:2000981; P:negative regulation of inner ear receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:2000974; P:negative regulation of pro-B cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000737; P:negative regulation of stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0021915; P:neural tube development; ISS:UniProtKB.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IGI:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; ISS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0031641; P:regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0050767; P:regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0072050; P:S-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0072086; P:specification of loop of Henle identity; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; ISS:UniProtKB.
//
ID   HES6_HUMAN              Reviewed;         224 AA.
AC   Q96HZ4; A8KAP6; Q53SN9; Q8N2J2; Q96T93; Q9P2S3;
DE   RecName: Full=Transcription cofactor HES-6;
DE   AltName: Full=C-HAIRY1;
DE   AltName: Full=Class B basic helix-loop-helix protein 41;
DE            Short=bHLHb41;
DE   AltName: Full=Hairy and enhancer of split 6;
GN   Name=HES6; Synonyms=BHLHB41;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HES7_HUMAN              Reviewed;         225 AA.
AC   Q9BYE0; F8VPC9;
DE   RecName: Full=Transcription factor HES-7;
DE            Short=hHes7;
DE   AltName: Full=Class B basic helix-loop-helix protein 37;
DE            Short=bHLHb37;
DE   AltName: Full=Hairy and enhancer of split 7;
DE   AltName: Full=bHLH factor Hes7;
GN   Name=HES7; Synonyms=BHLHB37;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0007498; P:mesoderm development; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0014807; P:regulation of somitogenesis; IEA:Ensembl.
DR   GO; GO:0048511; P:rhythmic process; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HESRG_HUMAN             Reviewed;         222 AA.
AC   Q1W209;
DE   RecName: Full=Embryonic stem cell-related gene protein;
DE            Short=hES cell-related gene protein;
GN   Name=HESRG;
//
ID   HESX1_HUMAN             Reviewed;         185 AA.
AC   Q9UBX0; Q52LC5; Q99667;
DE   RecName: Full=Homeobox expressed in ES cells 1;
DE   AltName: Full=Homeobox protein ANF;
DE            Short=hAnf;
GN   Name=HESX1; Synonyms=HANF;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0043584; P:nose development; IEA:Ensembl.
DR   GO; GO:0030916; P:otic vesicle formation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HEXA_HUMAN              Reviewed;         529 AA.
AC   P06865; Q53HS8; Q6AI32;
DE   RecName: Full=Beta-hexosaminidase subunit alpha;
DE            EC=3.2.1.52;
DE   AltName: Full=Beta-N-acetylhexosaminidase subunit alpha;
DE            Short=Hexosaminidase subunit A;
DE   AltName: Full=N-acetyl-beta-glucosaminidase subunit alpha;
DE   Flags: Precursor;
GN   Name=HEXA;
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Ensembl.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006689; P:ganglioside catabolic process; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0019953; P:sexual reproduction; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   HEXB_HUMAN              Reviewed;         556 AA.
AC   P07686;
DE   RecName: Full=Beta-hexosaminidase subunit beta;
DE            EC=3.2.1.52;
DE   AltName: Full=Beta-N-acetylhexosaminidase subunit beta;
DE            Short=Hexosaminidase subunit B;
DE   AltName: Full=Cervical cancer proto-oncogene 7 protein;
DE            Short=HCC-7;
DE   AltName: Full=N-acetyl-beta-glucosaminidase subunit beta;
DE   Contains:
DE     RecName: Full=Beta-hexosaminidase subunit beta chain B;
DE   Contains:
DE     RecName: Full=Beta-hexosaminidase subunit beta chain A;
DE   Flags: Precursor;
GN   Name=HEXB; ORFNames=HCC7;
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; TAS:ProtInc.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0043615; P:astrocyte cell migration; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:Ensembl.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006689; P:ganglioside catabolic process; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0008049; P:male courtship behavior; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IEA:Ensembl.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0007341; P:penetration of zona pellucida; IEA:Ensembl.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   HEXDC_HUMAN             Reviewed;         486 AA.
AC   Q8WVB3; B7UUP6; Q8IYN4; Q8TE81;
DE   RecName: Full=Hexosaminidase D;
DE            EC=3.2.1.52;
DE   AltName: Full=Beta-N-acetylhexosaminidase;
DE   AltName: Full=Beta-hexosaminidase D;
DE   AltName: Full=Hexosaminidase domain-containing protein;
DE   AltName: Full=N-acetyl-beta-galactosaminidase;
GN   Name=HEXDC;
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   HEXI1_HUMAN             Reviewed;         359 AA.
AC   O94992; B2R8Y5;
DE   RecName: Full=Protein HEXIM1;
DE   AltName: Full=Cardiac lineage protein 1;
DE   AltName: Full=Estrogen down-regulated gene 1 protein;
DE   AltName: Full=Hexamethylene bis-acetamide-inducible protein 1;
DE   AltName: Full=Menage a quatre protein 1;
GN   Name=HEXIM1; Synonyms=CLP1, EDG1, HIS1, MAQ1;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017069; F:snRNA binding; IDA:HGNC.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:HGNC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HEXI2_HUMAN             Reviewed;         286 AA.
AC   Q96MH2; D3DX66;
DE   RecName: Full=Protein HEXIM2;
DE   AltName: Full=Hexamethylene bis-acetamide-inducible protein 2;
GN   Name=HEXIM2; ORFNames=L3;
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0017069; F:snRNA binding; IDA:HGNC.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:HGNC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HEY1_HUMAN              Reviewed;         304 AA.
AC   Q9Y5J3; B2R883; Q5TZS3; Q8NAM2; Q9NYP4;
DE   RecName: Full=Hairy/enhancer-of-split related with YRPW motif protein 1;
DE   AltName: Full=Cardiovascular helix-loop-helix factor 2;
DE            Short=CHF-2;
DE   AltName: Full=Class B basic helix-loop-helix protein 31;
DE            Short=bHLHb31;
DE   AltName: Full=HES-related repressor protein 1;
DE   AltName: Full=Hairy and enhancer of split-related protein 1;
DE            Short=HESR-1;
DE   AltName: Full=Hairy-related transcription factor 1;
DE            Short=HRT-1;
DE            Short=hHRT1;
GN   Name=HEY1; Synonyms=BHLHB31, CHF2, HERP2, HESR1, HRT1;
DR   GO; GO:0035939; F:microsatellite binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0060842; P:arterial endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0003190; P:atrioventricular valve formation; ISS:BHF-UCL.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0060411; P:cardiac septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0035912; P:dorsal aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003199; P:endocardial cushion to mesenchymal transition involved in heart valve formation; IEA:Ensembl.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.
DR   GO; GO:0060347; P:heart trabecula formation; ISS:BHF-UCL.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; ISS:BHF-UCL.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; IC:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:2001212; P:regulation of vasculogenesis; ISS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
DR   GO; GO:0036304; P:umbilical cord morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
//
ID   HEY2_HUMAN              Reviewed;         337 AA.
AC   Q9UBP5;
DE   RecName: Full=Hairy/enhancer-of-split related with YRPW motif protein 2;
DE   AltName: Full=Cardiovascular helix-loop-helix factor 1;
DE            Short=hCHF1;
DE   AltName: Full=Class B basic helix-loop-helix protein 32;
DE            Short=bHLHb32;
DE   AltName: Full=HES-related repressor protein 2;
DE   AltName: Full=Hairy and enhancer of split-related protein 2;
DE            Short=HESR-2;
DE   AltName: Full=Hairy-related transcription factor 2;
DE            Short=HRT-2;
DE            Short=hHRT2;
DE   AltName: Full=Protein gridlock homolog;
GN   Name=HEY2; Synonyms=BHLHB32, CHF1, GRL, HERP, HERP1, HRT2;
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0035939; F:microsatellite binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0060842; P:arterial endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003171; P:atrioventricular valve development; IEA:Ensembl.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060411; P:cardiac septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060948; P:cardiac vascular smooth muscle cell development; IEA:Ensembl.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0060977; P:coronary vasculature morphogenesis; IEA:Ensembl.
DR   GO; GO:0035912; P:dorsal aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003199; P:endocardial cushion to mesenchymal transition involved in heart valve formation; IEA:Ensembl.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; ISS:BHF-UCL.
DR   GO; GO:0014031; P:mesenchymal cell development; ISS:BHF-UCL.
DR   GO; GO:0003150; P:muscular septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:2000723; P:negative regulation of cardiac vascular smooth muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0010621; P:negative regulation of transcription by transcription factor localization; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000820; P:negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060633; P:negative regulation of transcription initiation from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; IC:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0065004; P:protein-DNA complex assembly; IEA:Ensembl.
DR   GO; GO:0061156; P:pulmonary artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045607; P:regulation of auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:2001212; P:regulation of vasculogenesis; ISS:BHF-UCL.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
DR   GO; GO:0003195; P:tricuspid valve formation; IEA:Ensembl.
DR   GO; GO:0003186; P:tricuspid valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0036304; P:umbilical cord morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0097084; P:vascular smooth muscle cell development; IEP:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; ISS:UniProtKB.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
//
ID   HEYL_HUMAN              Reviewed;         328 AA.
AC   Q9NQ87; Q5TG99;
DE   RecName: Full=Hairy/enhancer-of-split related with YRPW motif-like protein;
DE            Short=hHeyL;
DE   AltName: Full=Class B basic helix-loop-helix protein 33;
DE            Short=bHLHb33;
DE   AltName: Full=Hairy-related transcription factor 3;
DE            Short=HRT-3;
DE            Short=hHRT3;
GN   Name=HEYL; Synonyms=BHLHB33, HRT3;
DR   GO; GO:0050683; F:AF-1 domain binding; IPI:UniProtKB.
DR   GO; GO:0035939; F:microsatellite binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000988; F:protein binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:UniProtKB.
DR   GO; GO:0032835; P:glomerulus development; IEA:Ensembl.
DR   GO; GO:0014031; P:mesenchymal cell development; ISS:BHF-UCL.
DR   GO; GO:2000824; P:negative regulation of androgen receptor activity; IDA:UniProtKB.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0072014; P:proximal tubule development; IEA:Ensembl.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   HFE_HUMAN               Reviewed;         348 AA.
AC   Q30201; B2CKL0; O75929; O75930; O75931; Q17RT0; Q96KU5; Q96KU6;
AC   Q96KU7; Q96KU8; Q9HC64; Q9HC68; Q9HC70; Q9HC83;
DE   RecName: Full=Hereditary hemochromatosis protein;
DE   AltName: Full=HLA-H;
DE   Flags: Precursor;
GN   Name=HFE; Synonyms=HLAH;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:ProtInc.
DR   GO; GO:0010106; P:cellular response to iron ion starvation; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0097459; P:iron ion import into cell; IDA:UniProtKB.
DR   GO; GO:0060586; P:multicellular organismal iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   HFM1_HUMAN              Reviewed;        1435 AA.
AC   A2PYH4; B1B0B6; Q8N9Q0;
DE   RecName: Full=Probable ATP-dependent DNA helicase HFM1;
DE            EC=3.6.4.12;
DE   AltName: Full=SEC63 domain-containing protein 1;
GN   Name=HFM1; Synonyms=SEC3D1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IEA:Ensembl.
//
ID   HG2A_HUMAN              Reviewed;         296 AA.
AC   P04233; A8K7R1; B4DNE8; D3DQG3; D3DQG4; Q14597; Q29832; Q5U0J8;
AC   Q8SNA0; Q8WLP6;
DE   RecName: Full=HLA class II histocompatibility antigen gamma chain;
DE   AltName: Full=HLA-DR antigens-associated invariant chain;
DE   AltName: Full=Ia antigen-associated invariant chain;
DE            Short=Ii;
DE   AltName: Full=p33;
DE   AltName: CD_antigen=CD74;
GN   Name=CD74; Synonyms=DHLAG;
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:BHF-UCL.
DR   GO; GO:0019955; F:cytokine binding; IPI:UniProtKB.
DR   GO; GO:0004896; F:cytokine receptor activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; TAS:UniProtKB.
DR   GO; GO:0035718; F:macrophage migration inhibitory factor binding; IPI:BHF-UCL.
DR   GO; GO:0042289; F:MHC class II protein binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0019883; P:antigen processing and presentation of endogenous antigen; NAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; IEA:Ensembl.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0035691; P:macrophage migration inhibitory factor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:0002906; P:negative regulation of mature B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0002792; P:negative regulation of peptide secretion; IDA:BHF-UCL.
DR   GO; GO:0045581; P:negative regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:BHF-UCL.
DR   GO; GO:2000343; P:positive regulation of chemokine (C-X-C motif) ligand 2 production; ISS:BHF-UCL.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; ISS:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0002830; P:positive regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; ISS:UniProtKB.
DR   GO; GO:0043030; P:regulation of macrophage activation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0045058; P:T cell selection; NAS:UniProtKB.
//
ID   HGB1A_HUMAN             Reviewed;         211 AA.
AC   B2RPK0;
DE   RecName: Full=Putative high mobility group protein B1-like 1;
DE   AltName: Full=High mobility group protein B1 pseudogene 1;
DE   AltName: Full=Putative high mobility group protein 1-like 1;
DE            Short=HMG-1L1;
GN   Name=HMGB1P1; Synonyms=HMG1L1, HMGB1L1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   HGD_HUMAN               Reviewed;         445 AA.
AC   Q93099; A8K417; B2R8Z0;
DE   RecName: Full=Homogentisate 1,2-dioxygenase;
DE            EC=1.13.11.5;
DE   AltName: Full=Homogentisate oxygenase;
DE   AltName: Full=Homogentisic acid oxidase;
DE   AltName: Full=Homogentisicase;
GN   Name=HGD; Synonyms=HGO;
DR   GO; GO:0004411; F:homogentisate 1,2-dioxygenase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006572; P:tyrosine catabolic process; TAS:ProtInc.
//
ID   HGFA_HUMAN              Reviewed;         655 AA.
AC   Q04756; Q14726; Q2M1W7; Q53X47;
DE   RecName: Full=Hepatocyte growth factor activator;
DE            Short=HGF activator;
DE            Short=HGFA;
DE            EC=3.4.21.-;
DE   Contains:
DE     RecName: Full=Hepatocyte growth factor activator short chain;
DE   Contains:
DE     RecName: Full=Hepatocyte growth factor activator long chain;
DE   Flags: Precursor;
GN   Name=HGFAC;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   HGFL_HUMAN              Reviewed;         711 AA.
AC   P26927; A6NLA3; A8MSX3; Q13350; Q14870; Q6GTN4;
DE   RecName: Full=Hepatocyte growth factor-like protein;
DE   AltName: Full=Macrophage stimulatory protein;
DE   AltName: Full=Macrophage-stimulating protein;
DE            Short=MSP;
DE   Contains:
DE     RecName: Full=Hepatocyte growth factor-like protein alpha chain;
DE   Contains:
DE     RecName: Full=Hepatocyte growth factor-like protein beta chain;
DE   Flags: Precursor;
GN   Name=MST1; Synonyms=D3F15S2, DNF15S2, HGFL;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   HGF_HUMAN               Reviewed;         728 AA.
AC   P14210; A1L3U6; Q02935; Q13494; Q14519; Q3KRB2; Q8TCE2; Q9BYL9;
AC   Q9BYM0; Q9UDU6;
DE   RecName: Full=Hepatocyte growth factor;
DE   AltName: Full=Hepatopoietin-A;
DE   AltName: Full=Scatter factor;
DE            Short=SF;
DE   Contains:
DE     RecName: Full=Hepatocyte growth factor alpha chain;
DE   Contains:
DE     RecName: Full=Hepatocyte growth factor beta chain;
DE   Flags: Precursor;
GN   Name=HGF; Synonyms=HPTA;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; TAS:HGNC.
DR   GO; GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0051450; P:myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:1901299; P:negative regulation of hydrogen peroxide-mediated programmed cell death; IDA:BHF-UCL.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; NAS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0060665; P:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; IDA:MGI.
//
ID   HGNAT_HUMAN             Reviewed;         663 AA.
AC   Q68CP4; B4E2V0;
DE   RecName: Full=Heparan-alpha-glucosaminide N-acetyltransferase;
DE            EC=2.3.1.78;
DE   AltName: Full=Transmembrane protein 76;
GN   Name=HGSNAT; Synonyms=TMEM76;
DR   GO; GO:0015019; F:heparan-alpha-glucosaminide N-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007041; P:lysosomal transport; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HGS_HUMAN               Reviewed;         777 AA.
AC   O14964; Q9NR36;
DE   RecName: Full=Hepatocyte growth factor-regulated tyrosine kinase substrate;
DE   AltName: Full=Hrs;
DE   AltName: Full=Protein pp110;
GN   Name=HGS; Synonyms=HRS;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; NAS:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:HGNC.
DR   GO; GO:0042176; P:regulation of protein catabolic process; TAS:HGNC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   HHATL_HUMAN             Reviewed;         504 AA.
AC   Q9HCP6; Q8TBG3; Q9ULP7;
DE   RecName: Full=Protein-cysteine N-palmitoyltransferase HHAT-like protein;
DE   AltName: Full=Glycerol uptake/transporter homolog;
DE   AltName: Full=Hedgehog acyltransferase-like protein;
GN   Name=HHATL; Synonyms=C3orf3, GUP1, KIAA1173;
DR   GO; GO:0060262; P:negative regulation of N-terminal protein palmitoylation; ISS:UniProtKB.
//
ID   HHCM_HUMAN              Reviewed;         467 AA.
AC   Q05877;
DE   RecName: Full=Hepatocellular carcinoma protein HHCM;
DE            Short=HHC(M);
//
ID   HHAT_HUMAN              Reviewed;         493 AA.
AC   Q5VTY9; B7Z4D5; B7Z5I1; B7Z868; B7ZA75; D3DT91; F5H444; Q17RZ7;
AC   Q4G0K3; Q5CZ95; Q5TGI2; Q9NVH9; Q9Y3N8;
DE   RecName: Full=Protein-cysteine N-palmitoyltransferase HHAT;
DE            EC=2.3.1.-;
DE   AltName: Full=Hedgehog acyltransferase;
DE   AltName: Full=Melanoma antigen recognized by T-cells 2;
DE            Short=MART-2;
DE   AltName: Full=Skinny hedgehog protein 1;
GN   Name=HHAT; Synonyms=MART2, SKI1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016409; F:palmitoyltransferase activity; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0018345; P:protein palmitoylation; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   HHEX_HUMAN              Reviewed;         270 AA.
AC   Q03014; B1AQ17; Q96CE9;
DE   RecName: Full=Hematopoietically-expressed homeobox protein HHEX;
DE            Short=Homeobox protein HEX;
DE   AltName: Full=Homeobox protein PRH;
GN   Name=HHEX; Synonyms=HEX, PRH, PRHX;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:BHF-UCL.
DR   GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0070491; F:repressing transcription factor binding; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0017025; F:TBP-class protein binding; TAS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IC:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0061009; P:common bile duct development; IEA:Ensembl.
DR   GO; GO:0071103; P:DNA conformation change; IDA:BHF-UCL.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0061010; P:gall bladder development; IEA:Ensembl.
DR   GO; GO:0061011; P:hepatic duct development; IEA:Ensembl.
DR   GO; GO:0061017; P:hepatoblast differentiation; IEA:Ensembl.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0022027; P:interkinetic nuclear migration; IEA:Ensembl.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:BHF-UCL.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0002573; P:myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; TAS:BHF-UCL.
DR   GO; GO:0010621; P:negative regulation of transcription by transcription factor localization; IC:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060431; P:primary lung bud formation; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   HHIP_HUMAN              Reviewed;         700 AA.
AC   Q96QV1; Q6PK09; Q8NCI7; Q9BXK3; Q9H1J4; Q9H7E7;
DE   RecName: Full=Hedgehog-interacting protein;
DE            Short=HHIP;
DE            Short=HIP;
DE   Flags: Precursor;
GN   Name=HHIP; Synonyms=HIP; ORFNames=UNQ5825/PRO19644;
DR   GO; GO:0097108; F:hedgehog family protein binding; IPI:BHF-UCL.
DR   GO; GO:0016901; F:oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IDA:UniProtKB.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   HHLA1_HUMAN             Reviewed;         531 AA.
AC   C9JL84;
DE   RecName: Full=HERV-H LTR-associating protein 1;
DE   Flags: Precursor;
GN   Name=HHLA1;
//
ID   HHLA3_HUMAN             Reviewed;         114 AA.
AC   Q9XRX5; D3DQ74; Q5VZP2; Q96FH5; Q9XRX4;
DE   RecName: Full=HERV-H LTR-associating protein 3;
DE   AltName: Full=Human endogenous retrovirus-H long terminal repeat-associating protein 3;
GN   Name=HHLA3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   HHLA2_HUMAN             Reviewed;         414 AA.
AC   Q9UM44; B4DKN2; D3DN60; Q9NWQ6;
DE   RecName: Full=HERV-H LTR-associating protein 2;
DE   AltName: Full=Human endogenous retrovirus-H long terminal repeat-associating protein 2;
DE   Flags: Precursor;
GN   Name=HHLA2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
//
ID   HIAL1_HUMAN             Reviewed;         506 AA.
AC   Q5SR56; Q3KQT4; Q53GU5; Q8WU95; Q96SM4;
DE   RecName: Full=Hippocampus abundant transcript-like protein 1;
GN   Name=HIATL1;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   HIAT1_HUMAN             Reviewed;         490 AA.
AC   Q96MC6; Q6P2N7; Q8N8K2; Q8NBV3; Q96NY0; Q9NT25;
DE   RecName: Full=Hippocampus abundant transcript 1 protein;
DE   AltName: Full=Putative tetracycline transporter-like protein;
GN   Name=HIAT1;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   HIAL2_HUMAN             Reviewed;         134 AA.
AC   Q5VZR4; Q9BSG7;
DE   RecName: Full=Hippocampus abundant transcript-like protein 2;
GN   Name=HIATL2;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   HIBCH_HUMAN             Reviewed;         386 AA.
AC   Q6NVY1; D3DPI4; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q92931; Q9BS94;
DE   RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial;
DE            EC=3.1.2.4;
DE   AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase;
DE            Short=HIB-CoA hydrolase;
DE            Short=HIBYL-CoA-H;
DE   Flags: Precursor;
GN   Name=HIBCH;
DR   GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006574; P:valine catabolic process; IEA:UniProtKB-UniPathway.
//
ID   HIC1_HUMAN              Reviewed;         733 AA.
AC   Q14526; D3DTI4;
DE   RecName: Full=Hypermethylated in cancer 1 protein;
DE            Short=Hic-1;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 29;
GN   Name=HIC1; Synonyms=ZBTB29;
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   HIC2_HUMAN              Reviewed;         615 AA.
AC   Q96JB3; Q504T6; Q96KR3; Q9NSM9; Q9UPX9;
DE   RecName: Full=Hypermethylated in cancer 2 protein;
DE            Short=Hic-2;
DE   AltName: Full=HIC1-related gene on chromosome 22 protein;
DE   AltName: Full=Hic-3;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 30;
GN   Name=HIC2; Synonyms=HRG22, KIAA1020, ZBTB30;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HID1_HUMAN              Reviewed;         788 AA.
AC   Q8IV36; Q8N5L6; Q8TE83; Q9NT34;
DE   RecName: Full=Protein HID1;
DE   AltName: Full=Down-regulated in multiple cancers 1;
DE   AltName: Full=HID1 domain-containing protein;
DE   AltName: Full=Protein hid-1 homolog;
GN   Name=HID1; Synonyms=C17orf28, DMC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006886; P:intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0031001; P:response to brefeldin A; IDA:UniProtKB.
//
ID   HIDE1_HUMAN             Reviewed;         230 AA.
AC   A8MVS5; B2RXI3;
DE   RecName: Full=Protein HIDE1;
DE   Flags: Precursor;
GN   Name=HIDE1; Synonyms=C19orf38;
//
ID   HIF1A_HUMAN             Reviewed;         826 AA.
AC   Q16665; C0LZJ3; Q53XP6; Q96PT9; Q9UPB1;
DE   RecName: Full=Hypoxia-inducible factor 1-alpha;
DE            Short=HIF-1-alpha;
DE            Short=HIF1-alpha;
DE   AltName: Full=ARNT-interacting protein;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP1;
DE   AltName: Full=Class E basic helix-loop-helix protein 78;
DE            Short=bHLHe78;
DE   AltName: Full=Member of PAS protein 1;
DE   AltName: Full=PAS domain-containing protein 8;
GN   Name=HIF1A; Synonyms=BHLHE78, MOP1, PASD8;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0019896; P:axon transport of mitochondrion; IMP:UniProtKB.
DR   GO; GO:0001922; P:B-1 B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0032963; P:collagen metabolic process; ISS:BHF-UCL.
DR   GO; GO:0002248; P:connective tissue replacement involved in inflammatory response wound healing; ISS:BHF-UCL.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051541; P:elastin metabolic process; ISS:BHF-UCL.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0061030; P:epithelial cell differentiation involved in mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060574; P:intestinal epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0006089; P:lactate metabolic process; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IC:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0045926; P:negative regulation of growth; IEA:Ensembl.
DR   GO; GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0021502; P:neural fold elevation formation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0032364; P:oxygen homeostasis; IDA:HGNC.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IC:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; TAS:BHF-UCL.
DR   GO; GO:0070101; P:positive regulation of chemokine-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IC:BHF-UCL.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; ISS:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IC:BHF-UCL.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IC:BHF-UCL.
DR   GO; GO:0046886; P:positive regulation of hormone biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; TAS:BHF-UCL.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IMP:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032909; P:regulation of transforming growth factor beta2 production; IMP:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:BHF-UCL.
DR   GO; GO:0010573; P:vascular endothelial growth factor production; IDA:BHF-UCL.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   HIF1N_HUMAN             Reviewed;         349 AA.
AC   Q9NWT6; D3DR69; Q5W147; Q969Q7; Q9NPV5;
DE   RecName: Full=Hypoxia-inducible factor 1-alpha inhibitor;
DE            EC=1.14.11.30;
DE            EC=1.14.11.n4;
DE   AltName: Full=Factor inhibiting HIF-1;
DE            Short=FIH-1;
DE   AltName: Full=Hypoxia-inducible factor asparagine hydroxylase;
GN   Name=HIF1AN; Synonyms=FIH1;
DR   GO; GO:0071532; F:ankyrin repeat binding; IPI:UniProtKB.
DR   GO; GO:0031406; F:carboxylic acid binding; IDA:UniProtKB.
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0005112; F:Notch binding; IPI:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; EXP:Reactome.
DR   GO; GO:0019826; F:oxygen sensor activity; NAS:UniProtKB.
DR   GO; GO:0036140; F:peptidyl-asparagine 3-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0036139; F:peptidyl-histidine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0061428; P:negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0042265; P:peptidyl-asparagine hydroxylation; IDA:UniProtKB.
DR   GO; GO:0042264; P:peptidyl-aspartic acid hydroxylation; IDA:UniProtKB.
DR   GO; GO:0036138; P:peptidyl-histidine hydroxylation; IDA:UniProtKB.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; NAS:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HIF3A_HUMAN             Reviewed;         669 AA.
AC   Q9Y2N7; B0M185; B4DNA2; Q58A43; Q66K72; Q8WXA1; Q96K34; Q9H7Z9;
AC   Q9HAI2;
DE   RecName: Full=Hypoxia-inducible factor 3-alpha;
DE            Short=HIF-3-alpha;
DE            Short=HIF3-alpha;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP7;
DE   AltName: Full=Class E basic helix-loop-helix protein 17;
DE            Short=bHLHe17;
DE   AltName: Full=HIF3-alpha-1;
DE   AltName: Full=Inhibitory PAS domain protein;
DE            Short=IPAS;
DE   AltName: Full=Member of PAS protein 7;
DE   AltName: Full=PAS domain-containing protein 7;
GN   Name=HIF3A; Synonyms=BHLHE17, MOP7, PASD7;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   HIG1A_HUMAN             Reviewed;          93 AA.
AC   Q9Y241; Q9UFZ2;
DE   RecName: Full=HIG1 domain family member 1A, mitochondrial;
DE   AltName: Full=Hypoxia-inducible gene 1 protein;
DE   AltName: Full=RCF1 homolog A;
DE            Short=RCF1a;
GN   Name=HIGD1A; Synonyms=HIG1; ORFNames=HSPC010;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HIG1B_HUMAN             Reviewed;          99 AA.
AC   Q9P298; D3DX57; Q9P297;
DE   RecName: Full=HIG1 domain family member 1B;
DE   AltName: Full=Protein CLST 11240;
GN   Name=HIGD1B;
//
ID   HIG1C_HUMAN             Reviewed;          97 AA.
AC   A8MV81;
DE   RecName: Full=HIG1 domain family member 1C;
GN   Name=HIGD1C; Synonyms=UBIE, UBIE2;
//
ID   HIG2A_HUMAN             Reviewed;         106 AA.
AC   Q9BW72;
DE   RecName: Full=HIG1 domain family member 2A, mitochondrial;
DE   AltName: Full=RCF1 homolog B;
DE            Short=RCF1b;
GN   Name=HIGD2A;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
//
ID   HIG2B_HUMAN             Reviewed;         106 AA.
AC   Q4VC39;
DE   RecName: Full=Putative HIG1 domain family member 2B;
DE   AltName: Full=HIG1 domain family member 2B pseudogene;
GN   Name=HIGD2B; Synonyms=HIGD2BP;
//
ID   HIKES_HUMAN             Reviewed;         197 AA.
AC   Q53FT3; Q8WVE8; Q9NVQ2; Q9NZZ1; Q9P022; Q9P0N1;
DE   RecName: Full=Protein Hikeshi;
GN   Name=C11orf73; ORFNames=HSPC138, HSPC179, HSPC248;
DR   GO; GO:0030544; F:Hsp70 protein binding; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
//
ID   HILS1_HUMAN             Reviewed;         231 AA.
AC   P60008;
DE   RecName: Full=Spermatid-specific linker histone H1-like protein;
GN   Name=HILS1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0006342; P:chromatin silencing; IDA:UniProtKB.
DR   GO; GO:0030261; P:chromosome condensation; IDA:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HINFP_HUMAN             Reviewed;         517 AA.
AC   Q9BQA5; B3KPH6; B4DWB4; E9PQF4; Q96E65; Q9Y4M7;
DE   RecName: Full=Histone H4 transcription factor;
DE   AltName: Full=Histone nuclear factor P;
DE            Short=HiNF-P;
DE   AltName: Full=MBD2-interacting zinc finger protein;
DE   AltName: Full=Methyl-CpG-binding protein 2-interacting zinc finger protein;
GN   Name=HINFP; Synonyms=MIZF, ZNF743;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0045445; P:myoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HINT1_HUMAN             Reviewed;         126 AA.
AC   P49773; Q9H5W8;
DE   RecName: Full=Histidine triad nucleotide-binding protein 1;
DE            EC=3.-.-.-;
DE   AltName: Full=Adenosine 5'-monophosphoramidase;
DE   AltName: Full=Protein kinase C inhibitor 1;
DE   AltName: Full=Protein kinase C-interacting protein 1;
DE            Short=PKCI-1;
GN   Name=HINT1; Synonyms=HINT, PKCI1, PRKCNH1;
DR   GO; GO:0016787; F:hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005080; F:protein kinase C binding; TAS:ProtInc.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0009154; P:purine ribonucleotide catabolic process; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HINT2_HUMAN             Reviewed;         163 AA.
AC   Q9BX68; Q5TCW3;
DE   RecName: Full=Histidine triad nucleotide-binding protein 2, mitochondrial;
DE            Short=HINT-2;
DE            EC=3.-.-.-;
DE   AltName: Full=HINT-3;
DE   AltName: Full=HIT-17kDa;
DE   AltName: Full=PKCI-1-related HIT protein;
DE   Flags: Precursor;
GN   Name=HINT2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
//
ID   HINT3_HUMAN             Reviewed;         182 AA.
AC   Q9NQE9; B3KQ91; Q8N0Y9;
DE   RecName: Full=Histidine triad nucleotide-binding protein 3;
DE            Short=HINT-3;
DE            EC=3.-.-.-;
GN   Name=HINT3;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
//
ID   HIP1R_HUMAN             Reviewed;        1068 AA.
AC   O75146; A6NHQ6; Q6NXG8; Q9UED9;
DE   RecName: Full=Huntingtin-interacting protein 1-related protein;
DE            Short=HIP1-related protein;
DE   AltName: Full=Huntingtin-interacting protein 12;
DE            Short=HIP-12;
GN   Name=HIP1R; Synonyms=HIP12, KIAA0655;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
//
ID   HIP1_HUMAN              Reviewed;        1037 AA.
AC   O00291; B4E3I7; E7ES17; O00328; Q2TB58; Q8TDL4;
DE   RecName: Full=Huntingtin-interacting protein 1;
DE            Short=HIP-1;
DE   AltName: Full=Huntingtin-interacting protein I;
DE            Short=HIP-I;
GN   Name=HIP1;
DR   GO; GO:0030276; F:clathrin binding; IDA:MGI.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048268; P:clathrin coat assembly; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HIPK1_HUMAN             Reviewed;        1210 AA.
AC   Q86Z02; A6NJ34; O75125; Q5SQL2; Q5SQL4; Q5SQL5; Q8IYD7; Q8NDN5;
AC   Q8NEB6; Q8TBZ1;
DE   RecName: Full=Homeodomain-interacting protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Nuclear body-associated kinase 2;
GN   Name=HIPK1; Synonyms=KIAA0630, MYAK, NBAK2;
DR   GuidetoPHARMACOLOGY; 2033; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0072577; P:endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001654; P:eye development; ISS:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0061072; P:iris morphogenesis; IEA:Ensembl.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0016926; P:protein desumoylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0010803; P:regulation of tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HIPK2_HUMAN             Reviewed;        1198 AA.
AC   Q9H2X6; Q75MR7; Q8WWI4; Q9H2Y1;
DE   RecName: Full=Homeodomain-interacting protein kinase 2;
DE            Short=hHIPk2;
DE            EC=2.7.11.1;
GN   Name=HIPK2;
DR   GuidetoPHARMACOLOGY; 2034; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0046790; F:virion binding; IPI:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:UniProtKB.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:BHF-UCL.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0001654; P:eye development; ISS:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; NAS:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; TAS:UniProtKB.
DR   GO; GO:0061072; P:iris morphogenesis; IEA:Ensembl.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; NAS:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0030578; P:PML body organization; TAS:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; ISS:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050882; P:voluntary musculoskeletal movement; IEA:Ensembl.
//
ID   HIPK3_HUMAN             Reviewed;        1215 AA.
AC   Q9H422; O14632; Q2PBG4; Q2PBG5; Q92632; Q9HAS2;
DE   RecName: Full=Homeodomain-interacting protein kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Androgen receptor-interacting nuclear protein kinase;
DE            Short=ANPK;
DE   AltName: Full=Fas-interacting serine/threonine-protein kinase;
DE            Short=FIST;
DE   AltName: Full=Homolog of protein kinase YAK1;
GN   Name=HIPK3; Synonyms=DYRK6, FIST3, PKY;
DR   GuidetoPHARMACOLOGY; 2035; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0009299; P:mRNA transcription; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HIPK4_HUMAN             Reviewed;         616 AA.
AC   Q8NE63; A8K863; Q96M54;
DE   RecName: Full=Homeodomain-interacting protein kinase 4;
DE            EC=2.7.11.1;
GN   Name=HIPK4;
DR   GuidetoPHARMACOLOGY; 2036; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   HIPL1_HUMAN             Reviewed;         782 AA.
AC   Q96JK4; A2RUF8; B2RN09; Q6UXX2;
DE   RecName: Full=HHIP-like protein 1;
DE   Flags: Precursor;
GN   Name=HHIPL1; Synonyms=HHIP2, KIAA1822; ORFNames=UNQ9245/PRO34761;
DR   GO; GO:0016901; F:oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   HIPL2_HUMAN             Reviewed;         724 AA.
AC   Q6UWX4; Q6GU65; Q96BT4; Q96BU5; Q9H8A0;
DE   RecName: Full=HHIP-like protein 2;
DE   Flags: Precursor;
GN   Name=HHIPL2; Synonyms=HHIP3, KIAA1822L; ORFNames=UNQ841/PRO1779;
DR   GO; GO:0016901; F:oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   HIRA_HUMAN              Reviewed;        1017 AA.
AC   P54198; Q05BU9; Q8IXN2;
DE   RecName: Full=Protein HIRA;
DE   AltName: Full=TUP1-like enhancer of split protein 1;
GN   Name=HIRA; Synonyms=DGCR1, HIR, TUPLE1;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HIRP3_HUMAN             Reviewed;         556 AA.
AC   Q9BW71; H3BSR3; O75707; O75708;
DE   RecName: Full=HIRA-interacting protein 3;
GN   Name=HIRIP3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006333; P:chromatin assembly or disassembly; TAS:ProtInc.
//
ID   HIS1_HUMAN              Reviewed;          57 AA.
AC   P15515;
DE   RecName: Full=Histatin-1;
DE   AltName: Full=Histidine-rich protein 1;
DE   AltName: Full=Post-PB protein;
DE            Short=PPB;
DE   Contains:
DE     RecName: Full=His1-(31-57)-peptide;
DE              Short=His1 31/57;
DE     AltName: Full=His1-(12-38)-peptide;
DE              Short=His1 12/38;
DE     AltName: Full=Histatin-2;
DE   Flags: Precursor;
GN   Name=HTN1; Synonyms=HIS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; NAS:UniProtKB.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   HIS3_HUMAN              Reviewed;          51 AA.
AC   P15516; Q16243; Q502Z1;
DE   RecName: Full=Histatin-3;
DE   AltName: Full=Basic histidine-rich protein;
DE            Short=Hst;
DE   AltName: Full=Histidine-rich protein 3;
DE   AltName: Full=PB;
DE   Contains:
DE     RecName: Full=Histatin-3;
DE   Contains:
DE     RecName: Full=His3-(20-44)-peptide;
DE              Short=His3 20/44;
DE     AltName: Full=His3-(1-25)-peptide;
DE              Short=His3 1/25;
DE     AltName: Full=Histatin-3 1/25;
DE     AltName: Full=Histatin-6;
DE   Contains:
DE     RecName: Full=His3-(20-43)-peptide;
DE              Short=His3 20/43;
DE     AltName: Full=His3-(1-24)-peptide;
DE              Short=His3 1/24;
DE     AltName: Full=Histatin-3 1/24;
DE     AltName: Full=Histatin-5;
DE   Contains:
DE     RecName: Full=His3-(20-32)-peptide;
DE              Short=His3 20/32;
DE     AltName: Full=His3-(1-13)-peptide;
DE              Short=His3 1/13;
DE     AltName: Full=Histatin-3 1/13;
DE   Contains:
DE     RecName: Full=His3-(20-31)-peptide;
DE              Short=His3 20/31;
DE     AltName: Full=His3-(1-12)-peptide;
DE              Short=His3 1/12;
DE     AltName: Full=Histatin-3 1/12;
DE   Contains:
DE     RecName: Full=His3-(20-30)-peptide;
DE              Short=His3 20/30;
DE     AltName: Full=His3-(1-11)-peptide;
DE              Short=His3 1/11;
DE     AltName: Full=Histatin-3 1/11;
DE   Contains:
DE     RecName: Full=His3-(24-32)-peptide;
DE              Short=His3 24/32;
DE     AltName: Full=His3-(5-13)-peptide;
DE              Short=His3 5/13;
DE     AltName: Full=Histatin-3 5/13;
DE   Contains:
DE     RecName: Full=His3-(24-31)-peptide;
DE              Short=His3 24/31;
DE     AltName: Full=His3-(5-12)-peptide;
DE              Short=His3 5/12;
DE     AltName: Full=Histatin-11;
DE     AltName: Full=Histatin-3 5/12;
DE   Contains:
DE     RecName: Full=His3-(24-30)-peptide;
DE              Short=His3 24/30;
DE     AltName: Full=His3-(5-11)-peptide;
DE              Short=His3 5/11;
DE     AltName: Full=Histatin-12;
DE     AltName: Full=Histatin-3 5/11;
DE   Contains:
DE     RecName: Full=His3-(25-32)-peptide;
DE              Short=His3 25/32;
DE     AltName: Full=His3-(6-13)-peptide;
DE              Short=His3 6/13;
DE     AltName: Full=Histatin-3 6/13;
DE   Contains:
DE     RecName: Full=His3-(25-30)-peptide;
DE              Short=His3 25/30;
DE     AltName: Full=His3-(6-11)-peptide;
DE              Short=His3 6/11;
DE     AltName: Full=Histatin-3 6/11;
DE   Contains:
DE     RecName: Full=His3-(26-32)-peptide;
DE              Short=His3 26/32;
DE     AltName: Full=His3-(7-13)-peptide;
DE              Short=His3 7/13;
DE     AltName: Full=Histatin-3 7/13;
DE   Contains:
DE     RecName: Full=His3-(26-31)-peptide;
DE              Short=His3 26/31;
DE     AltName: Full=His3-(7-12)-peptide;
DE              Short=His3 7/12;
DE     AltName: Full=Histatin-3 7/12;
DE   Contains:
DE     RecName: Full=His3-(26-30)-peptide;
DE              Short=His3 26/30;
DE     AltName: Full=His3-(7-11)-peptide;
DE              Short=His3 7/11;
DE     AltName: Full=Histatin-3 7/11;
DE   Contains:
DE     RecName: Full=His3-(31-51)-peptide;
DE              Short=His3 31/51;
DE     AltName: Full=His3-(12-32)-peptide;
DE              Short=His3 12/32;
DE     AltName: Full=Histatin-3 12/32;
DE     AltName: Full=Histatin-4;
DE   Contains:
DE     RecName: Full=His3-(31-44)-peptide;
DE              Short=His3 31/44;
DE     AltName: Full=His3-(12-25)-peptide;
DE              Short=His3 12/25;
DE     AltName: Full=Histatin-3 12/25;
DE     AltName: Full=Histatin-9;
DE   Contains:
DE     RecName: Full=His3-(31-43)-peptide;
DE              Short=His3 31/43;
DE     AltName: Full=His3-(12-24)-peptide;
DE              Short=His3 12/24;
DE     AltName: Full=Histatin-3 12/24;
DE     AltName: Full=Histatin-7;
DE   Contains:
DE     RecName: Full=His3-(32-44)-peptide;
DE              Short=His3 32/44;
DE     AltName: Full=His3-(13-25)-peptide;
DE              Short=His3 13/25;
DE     AltName: Full=Histatin-10;
DE     AltName: Full=Histatin-3 13/25;
DE   Contains:
DE     RecName: Full=His3-(32-43)-peptide;
DE              Short=His3 32-43;
DE     AltName: Full=His3-(13-24)-peptide;
DE              Short=His3 13/24;
DE     AltName: Full=Histatin-3 13/24;
DE     AltName: Full=Histatin-8;
DE   Contains:
DE     RecName: Full=His3-(33-44)-peptide;
DE              Short=His3 33/44;
DE     AltName: Full=His3-(14-25)-peptide;
DE              Short=His3 14/25;
DE     AltName: Full=Histatin-3 14/25;
DE   Contains:
DE     RecName: Full=His3-(33-43)-peptide;
DE              Short=His3 33/43;
DE     AltName: Full=His3-(14-24)-peptide;
DE              Short=His3 14/24;
DE     AltName: Full=Histatin-3 14/24;
DE   Contains:
DE     RecName: Full=His3-(34-44)-peptide;
DE              Short=His3 34/44;
DE     AltName: Full=His3-(15-25)-peptide;
DE              Short=His3 15/25;
DE     AltName: Full=Histatin-3 15/25;
DE   Contains:
DE     RecName: Full=His3-(34-43)-peptide;
DE              Short=His3 34/43;
DE     AltName: Full=His3-(15-24)-peptide;
DE              Short=His3 15/24;
DE     AltName: Full=Histatin-3 15/24;
DE   Contains:
DE     RecName: Full=His3-(45-51)-peptide;
DE              Short=His3 45/51;
DE     AltName: Full=His3-(26-32)-peptide;
DE              Short=His3 26/32;
DE     AltName: Full=Histatin-3 26/32;
DE   Contains:
DE     RecName: Full=His3-(47-51)-peptide;
DE              Short=His3 47/51;
DE     AltName: Full=His3-(28-32)-peptide;
DE              Short=His3 28/32;
DE     AltName: Full=Histatin-3 28/32;
DE   Contains:
DE     RecName: Full=His3-(48-51)-peptide;
DE              Short=His3 48/51;
DE     AltName: Full=His3-(29-32)-peptide;
DE              Short=His3 29/32;
DE     AltName: Full=Histatin-3 29/32;
DE   Flags: Precursor;
GN   Name=HTN3; Synonyms=HIS2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; NAS:UniProtKB.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
//
ID   HJURP_HUMAN             Reviewed;         748 AA.
AC   Q8NCD3; A8IRH5; B4DWR0; B4DZV4; Q9BUT2; Q9NSL8;
DE   RecName: Full=Holliday junction recognition protein;
DE   AltName: Full=14-3-3-associated AKT substrate;
DE   AltName: Full=Fetal liver-expressing gene 1 protein;
DE   AltName: Full=Up-regulated in lung cancer 9;
GN   Name=HJURP; Synonyms=FAKTS, FLEG1, URLC9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0051101; P:regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IDA:UniProtKB.
//
ID   HKDC1_HUMAN             Reviewed;         917 AA.
AC   Q2TB90; B5MDN9; Q2TB91; Q5VTC7; Q7Z373; Q8WU37; Q96EH2; Q9H5Y9;
DE   RecName: Full=Putative hexokinase HKDC1;
DE            EC=2.7.1.1;
DE   AltName: Full=Hexokinase domain-containing protein 1;
GN   Name=HKDC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IBA:RefGenome.
DR   GO; GO:0004340; F:glucokinase activity; IBA:RefGenome.
DR   GO; GO:0019158; F:mannokinase activity; IBA:RefGenome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IBA:GOC.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IBA:RefGenome.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IBA:GOC.
DR   GO; GO:0006096; P:glycolytic process; IBA:RefGenome.
DR   GO; GO:0019318; P:hexose metabolic process; IEA:UniProtKB-UniPathway.
//
ID   HKR1_HUMAN              Reviewed;         659 AA.
AC   P10072; A8MRS7; Q6PJD0; Q9BSW9; Q9UM09;
DE   RecName: Full=Krueppel-related zinc finger protein 1;
DE   AltName: Full=Protein HKR1;
DE   AltName: Full=Zinc finger protein 875;
GN   Name=HKR1; Synonyms=ZNF875;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HLAE_HUMAN              Reviewed;         358 AA.
AC   P13747; Q30169; Q9BT83; Q9GIY7; Q9GIY8;
DE   RecName: Full=HLA class I histocompatibility antigen, alpha chain E;
DE   AltName: Full=MHC class I antigen E;
DE   Flags: Precursor;
GN   Name=HLA-E; Synonyms=HLA-6.2, HLAE;
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProt.
DR   GO; GO:0042605; F:peptide antigen binding; IDA:UniProt.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0002476; P:antigen processing and presentation of endogenous peptide antigen via MHC class Ib; IDA:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002717; P:positive regulation of natural killer cell mediated immunity; IDA:UniProt.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0042270; P:protection from natural killer cell mediated cytotoxicity; IDA:UniProt.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   HLAF_HUMAN              Reviewed;         346 AA.
AC   P30511; Q5JQI8; Q5JQJ1; Q5SPT5; Q860R0; Q8MGQ1; Q8WLP5; Q95HC0;
AC   Q9TP68;
DE   RecName: Full=HLA class I histocompatibility antigen, alpha chain F;
DE   AltName: Full=CDA12;
DE   AltName: Full=HLA F antigen;
DE   AltName: Full=Leukocyte antigen F;
DE   AltName: Full=MHC class I antigen F;
DE   Flags: Precursor;
GN   Name=HLA-F; Synonyms=HLA-5.4, HLAF;
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IBA:RefGenome.
DR   GO; GO:0046978; F:TAP1 binding; IPI:UniProt.
DR   GO; GO:0046979; F:TAP2 binding; IPI:UniProt.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   HLAG_HUMAN              Reviewed;         338 AA.
AC   P17693;
DE   RecName: Full=HLA class I histocompatibility antigen, alpha chain G;
DE   AltName: Full=HLA G antigen;
DE   AltName: Full=MHC class I antigen G;
DE   Flags: Precursor;
GN   Name=HLA-G; Synonyms=HLA-6.0, HLAG;
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002767; P:immune response-inhibiting cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:2001199; P:negative regulation of dendritic cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:BHF-UCL.
DR   GO; GO:0045591; P:positive regulation of regulatory T cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0002666; P:positive regulation of T cell tolerance induction; IMP:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   HLAH_HUMAN              Reviewed;         362 AA.
AC   P01893;
DE   RecName: Full=Putative HLA class I histocompatibility antigen, alpha chain H;
DE   AltName: Full=HLA-12.4;
DE   AltName: Full=HLA-AR;
DE   AltName: Full=MHC class I antigen H;
DE   Flags: Precursor;
GN   Name=HLA-H; Synonyms=HLAH;
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
//
ID   HLF_HUMAN               Reviewed;         295 AA.
AC   Q16534; A8K1X8; Q6FHS9;
DE   RecName: Full=Hepatic leukemia factor;
GN   Name=HLF;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   HLPDA_HUMAN             Reviewed;          63 AA.
AC   Q9Y5L2; A4D0Z5; Q52LY5; Q53HJ7;
DE   RecName: Full=Hypoxia-inducible lipid droplet-associated protein;
DE   AltName: Full=Hypoxia-inducible gene 2 protein;
GN   Name=HILPDA; Synonyms=C7orf68, HIG2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0035425; P:autocrine signaling; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   HLTF_HUMAN              Reviewed;        1009 AA.
AC   Q14527; D3DNH3; Q14536; Q16051; Q7KYJ6; Q86YA5; Q92652; Q96KM9;
DE   RecName: Full=Helicase-like transcription factor;
DE            EC=3.6.4.-;
DE            EC=6.3.2.-;
DE   AltName: Full=DNA-binding protein/plasminogen activator inhibitor 1 regulator;
DE   AltName: Full=HIP116;
DE   AltName: Full=RING finger protein 80;
DE   AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3;
DE   AltName: Full=Sucrose nonfermenting protein 2-like 3;
GN   Name=HLTF; Synonyms=HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HLX_HUMAN               Reviewed;         488 AA.
AC   Q14774; B2R8A8; Q15988; Q59HE7; Q9NZ75;
DE   RecName: Full=H2.0-like homeobox protein;
DE   AltName: Full=Homeobox protein HB24;
DE   AltName: Full=Homeobox protein HLX1;
GN   Name=HLX; Synonyms=HLX1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045629; P:negative regulation of T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0045627; P:positive regulation of T-helper 1 cell differentiation; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HM13_HUMAN              Reviewed;         377 AA.
AC   Q8TCT9; B2RAY5; E1P5L3; Q15K36; Q540H8; Q5JWP2; Q5JWP3; Q5JWP4;
AC   Q5JWP5; Q7Z4F2; Q86Y35; Q95H87; Q9H110; Q9H111;
DE   RecName: Full=Minor histocompatibility antigen H13;
DE            EC=3.4.23.-;
DE   AltName: Full=Intramembrane protease 1;
DE            Short=IMP-1;
DE            Short=IMPAS-1;
DE            Short=hIMP1;
DE   AltName: Full=Presenilin-like protein 3;
DE   AltName: Full=Signal peptide peptidase;
GN   Name=HM13; Synonyms=H13, IMP1, PSL3, SPP; ORFNames=MSTP086;
DR   GO; GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.
//
ID   HM20A_HUMAN             Reviewed;         347 AA.
AC   Q9NP66; A6NHY3; D3DW78; Q53G31; Q9NSF6;
DE   RecName: Full=High mobility group protein 20A;
DE   AltName: Full=HMG box-containing protein 20A;
DE   AltName: Full=HMG domain-containing protein 1;
DE   AltName: Full=HMG domain-containing protein HMGX1;
GN   Name=HMG20A; Synonyms=HMGX1, HMGXB1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HM20B_HUMAN             Reviewed;         317 AA.
AC   Q9P0W2; A6NMS5; D6W616; Q6IBP8; Q8NBD5; Q9HD21; Q9Y491; Q9Y4A2;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;
DE            Short=SMARCE1-related protein;
DE   AltName: Full=BRCA2-associated factor 35;
DE   AltName: Full=HMG box-containing protein 20B;
DE   AltName: Full=HMG domain-containing protein 2;
DE   AltName: Full=HMG domain-containing protein HMGX2;
DE   AltName: Full=Sox-like transcriptional factor;
DE   AltName: Full=Structural DNA-binding protein BRAF35;
GN   Name=HMG20B; Synonyms=BRAF35, HMGX2, HMGXB2, SMARCE1R;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0033234; P:negative regulation of protein sumoylation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HMBX1_HUMAN             Reviewed;         420 AA.
AC   Q6NT76; A4K385; A8K3R8; B4DHY5; D3DSU0; Q3Y6P1; Q96GS5; Q9H701;
DE   RecName: Full=Homeobox-containing protein 1;
GN   Name=HMBOX1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HMCES_HUMAN             Reviewed;         354 AA.
AC   Q96FZ2; A6NJR9; Q96G34; Q9NRP3;
DE   RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein;
DE            Short=ES cell-specific 5hmC-binding protein;
DE   AltName: Full=Putative peptidase SRAPD1;
DE            EC=3.4.-.-;
DE   AltName: Full=SRAP domain-containing protein 1;
GN   Name=HMCES; Synonyms=C3orf37, DC12, SRAPD1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
//
ID   HMCN1_HUMAN             Reviewed;        5635 AA.
AC   Q96RW7; A6NGE3; Q5TYR7; Q96DN3; Q96DN8; Q96SC3;
DE   RecName: Full=Hemicentin-1;
DE   AltName: Full=Fibulin-6;
DE            Short=FIBL-6;
DE   Flags: Precursor;
GN   Name=HMCN1; Synonyms=FIBL6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   HMCN2_HUMAN             Reviewed;        5065 AA.
AC   Q8NDA2; Q8N225; Q8TCI8;
DE   RecName: Full=Hemicentin-2;
DE   Flags: Precursor;
GN   Name=HMCN2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
//
ID   HMCS1_HUMAN             Reviewed;         520 AA.
AC   Q01581; B2RDL8;
DE   RecName: Full=Hydroxymethylglutaryl-CoA synthase, cytoplasmic;
DE            Short=HMG-CoA synthase;
DE            EC=2.3.3.10;
DE   AltName: Full=3-hydroxy-3-methylglutaryl coenzyme A synthase;
GN   Name=HMGCS1; Synonyms=HMGCS;
DR   GuidetoPHARMACOLOGY; 638; -.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004421; F:hydroxymethylglutaryl-CoA synthase activity; TAS:ProtInc.
DR   GO; GO:0016853; F:isomerase activity; IEA:Ensembl.
DR   GO; GO:0043177; F:organic acid binding; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071397; P:cellular response to cholesterol; IEA:Ensembl.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0055094; P:response to lipoprotein particle; IEA:Ensembl.
DR   GO; GO:0009645; P:response to low light intensity stimulus; IEA:Ensembl.
DR   GO; GO:0014074; P:response to purine-containing compound; IEA:Ensembl.
DR   GO; GO:0046690; P:response to tellurium ion; IEA:Ensembl.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HMCS2_HUMAN             Reviewed;         508 AA.
AC   P54868; B7Z8R3; D3Y5K6; Q5SZU2; Q6IBF4;
DE   RecName: Full=Hydroxymethylglutaryl-CoA synthase, mitochondrial;
DE            Short=HMG-CoA synthase;
DE            EC=2.3.3.10;
DE   AltName: Full=3-hydroxy-3-methylglutaryl coenzyme A synthase;
DE   Flags: Precursor;
GN   Name=HMGCS2;
DR   GO; GO:0004421; F:hydroxymethylglutaryl-CoA synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046950; P:cellular ketone body metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   GO; GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HMDH_HUMAN              Reviewed;         888 AA.
AC   P04035; B7Z3Y9; Q8N190;
DE   RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase;
DE            Short=HMG-CoA reductase;
DE            EC=1.1.1.34;
GN   Name=HMGCR;
DR   GuidetoPHARMACOLOGY; 639; -.
DR   GO; GO:0050662; F:coenzyme binding; IDA:UniProtKB.
DR   GO; GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0042282; F:hydroxymethylglutaryl-CoA reductase activity; IDA:UniProtKB.
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0010664; P:negative regulation of striated muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045908; P:negative regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0061045; P:negative regulation of wound healing; IEA:Ensembl.
DR   GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006743; P:ubiquinone metabolic process; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   HME1_HUMAN              Reviewed;         392 AA.
AC   Q05925; Q4ZG44;
DE   RecName: Full=Homeobox protein engrailed-1;
DE            Short=Homeobox protein en-1;
DE            Short=Hu-En-1;
GN   Name=EN1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0030917; P:midbrain-hindbrain boundary development; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   HME2_HUMAN              Reviewed;         333 AA.
AC   P19622; A4D252; Q549U3; Q9UD58;
DE   RecName: Full=Homeobox protein engrailed-2;
DE            Short=Homeobox protein en-2;
DE            Short=Hu-En-2;
GN   Name=EN2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   HMGA1_HUMAN             Reviewed;         107 AA.
AC   P17096; P10910; Q5T6U9; Q9UKB0;
DE   RecName: Full=High mobility group protein HMG-I/HMG-Y;
DE            Short=HMG-I(Y);
DE   AltName: Full=High mobility group AT-hook protein 1;
DE            Short=High mobility group protein A1;
DE   AltName: Full=High mobility group protein R;
GN   Name=HMGA1; Synonyms=HMGIY;
DR   GO; GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; IDA:UniProtKB.
DR   GO; GO:0003680; F:AT DNA binding; TAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0042975; F:peroxisome proliferator activated receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IDA:UniProtKB.
DR   GO; GO:0046965; F:retinoid X receptor binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; NAS:UniProtKB.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0031936; P:negative regulation of chromatin silencing; TAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006337; P:nucleosome disassembly; TAS:UniProtKB.
DR   GO; GO:0090402; P:oncogene-induced cell senescence; IDA:UniProtKB.
DR   GO; GO:2000774; P:positive regulation of cellular senescence; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0035986; P:senescence-associated heterochromatin focus assembly; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   HMGA2_HUMAN             Reviewed;         109 AA.
AC   P52926; E7EP85; E7EWA2; Q1M182; Q1M185; Q1M186; Q1M187; Q1M188;
DE   RecName: Full=High mobility group protein HMGI-C;
DE   AltName: Full=High mobility group AT-hook protein 2;
GN   Name=HMGA2; Synonyms=HMGIC;
DR   GO; GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; IDA:UniProtKB.
DR   GO; GO:0003680; F:AT DNA binding; IDA:UniProtKB.
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IMP:UniProtKB.
DR   GO; GO:0035497; F:cAMP response element binding; IDA:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0004677; F:DNA-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0035501; F:MH1 domain binding; IDA:UniProtKB.
DR   GO; GO:0035500; F:MH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000975; F:regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0035988; P:chondrocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:UniProtKB.
DR   GO; GO:0031052; P:chromosome breakage; IDA:UniProtKB.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.
DR   GO; GO:0035987; P:endodermal cell differentiation; IMP:UniProtKB.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IMP:UniProtKB.
DR   GO; GO:0060613; P:fat pad development; IEA:Ensembl.
DR   GO; GO:0031507; P:heterochromatin assembly; IDA:UniProtKB.
DR   GO; GO:0035978; P:histone H2A-S139 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; IMP:UniProtKB.
DR   GO; GO:0048333; P:mesodermal cell differentiation; IMP:UniProtKB.
DR   GO; GO:0003131; P:mesodermal-endodermal cell signaling; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:2001033; P:negative regulation of double-strand break repair via nonhomologous end joining; IDA:UniProtKB.
DR   GO; GO:0033144; P:negative regulation of intracellular steroid hormone receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0090402; P:oncogene-induced cell senescence; IDA:UniProtKB.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:2000685; P:positive regulation of cellular response to X-ray; IDA:UniProtKB.
DR   GO; GO:2000774; P:positive regulation of cellular senescence; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010564; P:regulation of cell cycle process; IDA:UniProtKB.
DR   GO; GO:2001038; P:regulation of cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0060123; P:regulation of growth hormone secretion; IEA:Ensembl.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0035986; P:senescence-associated heterochromatin focus assembly; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0048863; P:stem cell differentiation; IEP:UniProtKB.
//
ID   HMGB1_HUMAN             Reviewed;         215 AA.
AC   P09429; A5D8W9; Q14321; Q5T7C3; Q6IBE1;
DE   RecName: Full=High mobility group protein B1;
DE   AltName: Full=High mobility group protein 1;
DE            Short=HMG-1;
GN   Name=HMGB1; Synonyms=HMG1;
DR   GO; GO:0042056; F:chemoattractant activity; ISS:UniProtKB.
DR   GO; GO:0005125; F:cytokine activity; ISS:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; ISS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IMP:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; ISS:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006288; P:base-excision repair, DNA ligation; IDA:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; ISS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; ISS:UniProtKB.
DR   GO; GO:0006265; P:DNA topological change; ISS:UniProtKB.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001773; P:myeloid dendritic cell activation; ISS:UniProtKB.
DR   GO; GO:2000426; P:negative regulation of apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0017055; P:negative regulation of RNA polymerase II transcriptional preinitiation complex assembly; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; ISS:GOC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0033151; P:V(D)J recombination; IDA:UniProtKB.
//
ID   HMGB4_HUMAN             Reviewed;         186 AA.
AC   Q8WW32; B2R4X7; Q0QWA4;
DE   RecName: Full=High mobility group protein B4;
GN   Name=HMGB4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   HMGB3_HUMAN             Reviewed;         200 AA.
AC   O15347; O95556; Q6NS40;
DE   RecName: Full=High mobility group protein B3;
DE   AltName: Full=High mobility group protein 2a;
DE            Short=HMG-2a;
DE   AltName: Full=High mobility group protein 4;
DE            Short=HMG-4;
GN   Name=HMGB3; Synonyms=HMG2A, HMG4;
DR   GO; GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   HMGB2_HUMAN             Reviewed;         209 AA.
AC   P26583; B2R4K8; D3DP37; Q5U072;
DE   RecName: Full=High mobility group protein B2;
DE   AltName: Full=High mobility group protein 2;
DE            Short=HMG-2;
GN   Name=HMGB2; Synonyms=HMG2;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; IGI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006288; P:base-excision repair, DNA ligation; IDA:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; ISS:UniProtKB.
DR   GO; GO:0006265; P:DNA topological change; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0032075; P:positive regulation of nuclease activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
DR   GO; GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
//
ID   HMGC2_HUMAN             Reviewed;         370 AA.
AC   Q8TB92; B1AQ42; B3KNV0; B7Z1S7; F8W793; Q6ZSA9;
DE   RecName: Full=3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic;
DE            EC=4.1.3.4;
DE   AltName: Full=3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1;
DE   AltName: Full=Endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase;
DE            Short=er-cHL;
GN   Name=HMGCLL1;
DR   GO; GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; ISS:UniProtKB.
DR   GO; GO:0046951; P:ketone body biosynthetic process; IDA:UniProtKB.
//
ID   HMGCL_HUMAN             Reviewed;         325 AA.
AC   P35914; B4DUP4; B7UCC6; D3Y5K7; Q6IBC0; Q96FP8;
DE   RecName: Full=Hydroxymethylglutaryl-CoA lyase, mitochondrial;
DE            Short=HL;
DE            Short=HMG-CoA lyase;
DE            EC=4.1.3.4;
DE   AltName: Full=3-hydroxy-3-methylglutarate-CoA lyase;
DE   Flags: Precursor;
GN   Name=HMGCL;
DR   GO; GO:0031406; F:carboxylic acid binding; IEA:Ensembl.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IEA:Ensembl.
DR   GO; GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0046950; P:cellular ketone body metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0046951; P:ketone body biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006552; P:leucine catabolic process; NAS:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HMGN1_HUMAN             Reviewed;         100 AA.
AC   P05114; Q3KQR8;
DE   RecName: Full=Non-histone chromosomal protein HMG-14;
DE   AltName: Full=High mobility group nucleosome-binding domain-containing protein 1;
GN   Name=HMGN1; Synonyms=HMG14;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; IEA:Ensembl.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; TAS:ProtInc.
DR   GO; GO:0048597; P:post-embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0000720; P:pyrimidine dimer repair by nucleotide-excision repair; IEA:Ensembl.
DR   GO; GO:0040034; P:regulation of development, heterochronic; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010224; P:response to UV-B; IEA:Ensembl.
DR   GO; GO:0010225; P:response to UV-C; IEA:Ensembl.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IEA:Ensembl.
//
ID   HMGN2_HUMAN             Reviewed;          90 AA.
AC   P05204; Q0VGD5; Q6FGI5; Q96C64;
DE   RecName: Full=Non-histone chromosomal protein HMG-17;
DE   AltName: Full=High mobility group nucleosome-binding domain-containing protein 2;
GN   Name=HMGN2; Synonyms=HMG17;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   HMGN3_HUMAN             Reviewed;          99 AA.
AC   Q15651; B2RD37; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7;
DE   RecName: Full=High mobility group nucleosome-binding domain-containing protein 3;
DE   AltName: Full=Thyroid receptor-interacting protein 7;
DE            Short=TR-interacting protein 7;
DE            Short=TRIP-7;
GN   Name=HMGN3; Synonyms=TRIP7; ORFNames=PNAS-24;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
//
ID   HMGN5_HUMAN             Reviewed;         282 AA.
AC   P82970; Q5JSL1;
DE   RecName: Full=High mobility group nucleosome-binding domain-containing protein 5;
DE   AltName: Full=Nucleosome-binding protein 1;
GN   Name=HMGN5; Synonyms=NSBP1;
DR   GO; GO:0003682; F:chromatin binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HMGN4_HUMAN             Reviewed;          90 AA.
AC   O00479; B2R4I6; Q53XL9;
DE   RecName: Full=High mobility group nucleosome-binding domain-containing protein 4;
DE   AltName: Full=Non-histone chromosomal protein HMG-17-like 3;
DE            Short=Non-histone chromosomal protein;
GN   Name=HMGN4; Synonyms=HMG17L3, NHC;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   HMGX3_HUMAN             Reviewed;        1538 AA.
AC   Q12766; G5E9Y4; Q86UG3; Q9UMF4;
DE   RecName: Full=HMG domain-containing protein 3;
DE   AltName: Full=HMG box-containing protein 3;
DE   AltName: Full=Protein SMF;
GN   Name=HMGXB3; Synonyms=KIAA0194, SMF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; NAS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; NAS:GOC.
//
ID   HMGX4_HUMAN             Reviewed;         601 AA.
AC   Q9UGU5; O75672; O75673; Q9UMT5;
DE   RecName: Full=HMG domain-containing protein 4;
DE   AltName: Full=HMG box-containing protein 4;
DE   AltName: Full=High mobility group protein 2-like 1;
DE   AltName: Full=Protein HMGBCG;
GN   Name=HMGXB4; Synonyms=HMG2L1, HMGBCG;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008333; P:endosome to lysosome transport; NAS:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   HMHA1_HUMAN             Reviewed;        1136 AA.
AC   Q92619; B4DTS4; F6QP70; Q6P189; Q7LE26; Q86WS1; Q8HX84; Q9GJN9;
AC   Q9GJP0; Q9GJP1; Q9MY24;
DE   RecName: Full=Minor histocompatibility protein HA-1;
DE   Contains:
DE     RecName: Full=Minor histocompatibility antigen HA-1;
DE              Short=mHag HA-1;
GN   Name=HMHA1; Synonyms=KIAA0223;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   HMHB1_HUMAN             Reviewed;          41 AA.
AC   O97980; Q9MY25;
DE   RecName: Full=Minor histocompatibility protein HB-1;
DE   Contains:
DE     RecName: Full=Minor histocompatibility antigen HB-1;
DE              Short=mHag HB-1;
GN   Name=HMHB1;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   HMMR_HUMAN              Reviewed;         724 AA.
AC   O75330; A8K3G2; B4E114; D3DQK9; D3DQL0; E9PCS0; Q32N02; Q92767;
DE   RecName: Full=Hyaluronan mediated motility receptor;
DE   AltName: Full=Intracellular hyaluronic acid-binding protein;
DE   AltName: Full=Receptor for hyaluronan-mediated motility;
DE   AltName: CD_antigen=CD168;
GN   Name=HMMR; Synonyms=IHABP, RHAMM;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HMN10_HUMAN             Reviewed;          24 AA.
AC   P0CJ77;
DE   RecName: Full=Humanin-like protein 10;
DE            Short=HN10;
DE   AltName: Full=MT-RNR2-like protein 10;
GN   Name=MTRNR2L10;
//
ID   HMN2_HUMAN              Reviewed;          28 AA.
AC   P0CJ69;
DE   RecName: Full=Humanin-like protein 2;
DE            Short=HN2;
DE   AltName: Full=MT-RNR2-like protein 2;
GN   Name=MTRNR2L2;
//
ID   HMN1_HUMAN              Reviewed;          24 AA.
AC   P0CJ68;
DE   RecName: Full=Humanin-like protein 1;
DE            Short=HN1;
DE   AltName: Full=MT-RNR2-like protein 1;
GN   Name=MTRNR2L1;
//
ID   HMN3_HUMAN              Reviewed;          24 AA.
AC   P0CJ70;
DE   RecName: Full=Humanin-like protein 3;
DE            Short=HN3;
DE   AltName: Full=MT-RNR2-like protein 3;
GN   Name=MTRNR2L3;
//
ID   HMN5_HUMAN              Reviewed;          24 AA.
AC   P0CJ72;
DE   RecName: Full=Humanin-like protein 5;
DE            Short=HN5;
DE   AltName: Full=MT-RNR2-like protein 5;
GN   Name=MTRNR2L5;
//
ID   HMN4_HUMAN              Reviewed;          28 AA.
AC   P0CJ71;
DE   RecName: Full=Humanin-like protein 4;
DE            Short=HN4;
DE   AltName: Full=MT-RNR2-like protein 4;
GN   Name=MTRNR2L4;
//
ID   HMN6_HUMAN              Reviewed;          24 AA.
AC   P0CJ73;
DE   RecName: Full=Humanin-like protein 6;
DE            Short=HN6;
DE   AltName: Full=MT-RNR2-like protein 6;
GN   Name=MTRNR2L6;
//
ID   HMN7_HUMAN              Reviewed;          24 AA.
AC   P0CJ74;
DE   RecName: Full=Humanin-like protein 7;
DE            Short=HN7;
DE   AltName: Full=MT-RNR2-like protein 7;
GN   Name=MTRNR2L7;
//
ID   HMN8_HUMAN              Reviewed;          24 AA.
AC   P0CJ75;
DE   RecName: Full=Humanin-like protein 8;
DE            Short=HN8;
DE   AltName: Full=MT-RNR2-like protein 8;
GN   Name=MTRNR2L8;
//
ID   HMN9_HUMAN              Reviewed;          24 AA.
AC   P0CJ76;
DE   RecName: Full=Humanin-like protein 9;
DE            Short=HN9;
DE   AltName: Full=MT-RNR2-like protein 9;
GN   Name=MTRNR2L9;
//
ID   HMOX1_HUMAN             Reviewed;         288 AA.
AC   P09601;
DE   RecName: Full=Heme oxygenase 1;
DE            Short=HO-1;
DE            EC=1.14.99.3;
GN   Name=HMOX1; Synonyms=HO, HO1;
DR   GO; GO:0019899; F:enzyme binding; ISS:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:BHF-UCL.
DR   GO; GO:0004392; F:heme oxygenase (decyclizing) activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004630; F:phospholipase D activity; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0008219; P:cell death; ISS:BHF-UCL.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0031670; P:cellular response to nutrient; IEA:Ensembl.
DR   GO; GO:0001935; P:endothelial cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007588; P:excretion; IC:BHF-UCL.
DR   GO; GO:0042167; P:heme catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006788; P:heme oxidation; IDA:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:BHF-UCL.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; TAS:BHF-UCL.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:0002686; P:negative regulation of leukocyte migration; TAS:BHF-UCL.
DR   GO; GO:0032764; P:negative regulation of mast cell cytokine production; IEA:Ensembl.
DR   GO; GO:0043305; P:negative regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0010656; P:negative regulation of muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IC:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0045765; P:regulation of angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; ISS:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; ISS:BHF-UCL.
DR   GO; GO:0035094; P:response to nicotine; IDA:BHF-UCL.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0014806; P:smooth muscle hyperplasia; TAS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0002246; P:wound healing involved in inflammatory response; IMP:BHF-UCL.
//
ID   HMOX2_HUMAN             Reviewed;         316 AA.
AC   P30519; A8MT35; D3DUD5; O60605;
DE   RecName: Full=Heme oxygenase 2;
DE            Short=HO-2;
DE            EC=1.14.99.3;
GN   Name=HMOX2; Synonyms=HO2;
DR   GO; GO:0004392; F:heme oxygenase (decyclizing) activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0042167; P:heme catabolic process; TAS:Reactome.
DR   GO; GO:0006788; P:heme oxidation; IEA:InterPro.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   HMR1_HUMAN              Reviewed;         341 AA.
AC   Q95460; A8K2V9; B4E3B1; O97985; O97986; Q53GM1; Q95HB8; Q9MY23;
AC   Q9NPL2; Q9TQB3; Q9TQB9; Q9TQK3;
DE   RecName: Full=Major histocompatibility complex class I-related gene protein;
DE            Short=MHC class I-related gene protein;
DE   AltName: Full=Class I histocompatibility antigen-like protein;
DE   Flags: Precursor;
GN   Name=MR1;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0032393; F:MHC class I receptor activity; TAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
DR   GO; GO:0002367; P:cytokine production involved in immune response; IEA:Ensembl.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0032611; P:interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0032620; P:interleukin-17 production; IEA:Ensembl.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   HMSDV_HUMAN             Reviewed;          53 AA.
AC   P0C7T4;
DE   RecName: Full=Minor histocompatibility protein HMSD variant form;
DE            Short=HSMD-v;
DE   Contains:
DE     RecName: Full=Minor histocompatibility antigen ACC-6;
DE              Short=mHA ACC-6;
GN   Name=HMSD; Synonyms=C18orf53;
//
ID   HMSD_HUMAN              Reviewed;         139 AA.
AC   A8MTL9;
DE   RecName: Full=Serpin-like protein HMSD;
DE   AltName: Full=Minor histocompatibility protein HMSD;
DE   AltName: Full=Minor histocompatibility serpin domain-containing protein;
DE   Flags: Precursor;
GN   Name=HMSD;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   HMX1_HUMAN              Reviewed;         348 AA.
AC   Q9NP08;
DE   RecName: Full=Homeobox protein HMX1;
DE   AltName: Full=Homeobox protein H6;
GN   Name=HMX1; Synonyms=H6;
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HMX2_HUMAN              Reviewed;         273 AA.
AC   A2RU54; B2RNV5;
DE   RecName: Full=Homeobox protein HMX2;
DE   AltName: Full=Homeobox protein H6 family member 2;
GN   Name=HMX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HMX3_HUMAN              Reviewed;         357 AA.
AC   A6NHT5; A8MU06;
DE   RecName: Full=Homeobox protein HMX3;
DE   AltName: Full=Homeobox protein H6 family member 3;
DE   AltName: Full=Homeobox protein Nkx-5.1;
GN   Name=HMX3; Synonyms=NKX-5.1, NKX5-1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HN1L_HUMAN              Reviewed;         190 AA.
AC   Q9H910; B1AJY2; Q6EIC7;
DE   RecName: Full=Hematological and neurological expressed 1-like protein;
DE            Short=HN1-like protein;
GN   Name=HN1L; Synonyms=C16orf34; ORFNames=L11;
//
ID   HN1_HUMAN               Reviewed;         154 AA.
AC   Q9UK76; B2R6K3; Q53FG7; Q7Z2D2; Q7Z2F0;
DE   RecName: Full=Hematological and neurological expressed 1 protein;
DE   AltName: Full=Androgen-regulated protein 2;
DE   Contains:
DE     RecName: Full=Hematological and neurological expressed 1 protein, N-terminally processed;
GN   Name=HN1; Synonyms=ARM2;
//
ID   HNF1A_HUMAN             Reviewed;         631 AA.
AC   P20823; A5Z2R8; E0YMJ5; E0YMK0; E0YMK1; E2I9R4; E2I9R5; F5H5U3;
AC   Q2M3H2; Q99861;
DE   RecName: Full=Hepatocyte nuclear factor 1-alpha;
DE            Short=HNF-1-alpha;
DE            Short=HNF-1A;
DE   AltName: Full=Liver-specific transcription factor LF-B1;
DE            Short=LFB1;
DE   AltName: Full=Transcription factor 1;
DE            Short=TCF-1;
GN   Name=HNF1A; Synonyms=TCF1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
DR   GO; GO:0046323; P:glucose import; IMP:UniProtKB.
DR   GO; GO:0030073; P:insulin secretion; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IGI:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0035623; P:renal glucose absorption; IMP:UniProtKB.
//
ID   HNF1B_HUMAN             Reviewed;         557 AA.
AC   P35680; B4DKM3; E0YMJ9;
DE   RecName: Full=Hepatocyte nuclear factor 1-beta;
DE            Short=HNF-1-beta;
DE            Short=HNF-1B;
DE   AltName: Full=Homeoprotein LFB3;
DE   AltName: Full=Transcription factor 2;
DE            Short=TCF-2;
DE   AltName: Full=Variant hepatic nuclear factor 1;
DE            Short=vHNF1;
GN   Name=HNF1B; Synonyms=TCF2;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IMP:UniProtKB.
DR   GO; GO:0001714; P:endodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0048806; P:genitalia development; IMP:UniProtKB.
DR   GO; GO:0061017; P:hepatoblast differentiation; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0001826; P:inner cell mass cell differentiation; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IDA:UniProtKB.
DR   GO; GO:0072181; P:mesonephric duct formation; IEA:Ensembl.
DR   GO; GO:0061296; P:negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis; IEA:Ensembl.
DR   GO; GO:1900212; P:negative regulation of mesenchymal cell apoptotic process involved in metanephros development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0039020; P:pronephric nephron tubule development; IGI:UniProtKB.
DR   GO; GO:0048793; P:pronephros development; IMP:UniProtKB.
DR   GO; GO:0072095; P:regulation of branch elongation involved in ureteric bud branching; IEA:Ensembl.
DR   GO; GO:0042663; P:regulation of endodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0035565; P:regulation of pronephros size; IMP:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0060677; P:ureteric bud elongation; IEA:Ensembl.
//
ID   HNF4G_HUMAN             Reviewed;         408 AA.
AC   Q14541; Q7Z2V9; Q9UH81; Q9UIS6;
DE   RecName: Full=Hepatocyte nuclear factor 4-gamma;
DE            Short=HNF-4-gamma;
DE   AltName: Full=Nuclear receptor subfamily 2 group A member 2;
GN   Name=HNF4G; Synonyms=NR2A2;
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   HNF4A_HUMAN             Reviewed;         474 AA.
AC   P41235; A5JW41; B2RPP8; O00659; O00723; Q14540; Q5QPB8; Q6B4V5;
AC   Q6B4V6; Q6B4V7; Q92653; Q92654; Q92655; Q99864; Q9NQH0;
DE   RecName: Full=Hepatocyte nuclear factor 4-alpha;
DE            Short=HNF-4-alpha;
DE   AltName: Full=Nuclear receptor subfamily 2 group A member 1;
DE   AltName: Full=Transcription factor 14;
DE            Short=TCF-14;
DE   AltName: Full=Transcription factor HNF-4;
GN   Name=HNF4A; Synonyms=HNF4, NR2A1, TCF14;
DR   GuidetoPHARMACOLOGY; 608; -.
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0005504; F:fatty acid binding; IDA:BHF-UCL.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IDA:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; IMP:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0006591; P:ornithine metabolic process; IMP:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:2000189; P:positive regulation of cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0010470; P:regulation of gastrulation; IEA:Ensembl.
DR   GO; GO:0060398; P:regulation of growth hormone receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; ISS:BHF-UCL.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; ISS:BHF-UCL.
DR   GO; GO:0007548; P:sex differentiation; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IMP:BHF-UCL.
//
ID   HNF6_HUMAN              Reviewed;         465 AA.
AC   Q9UBC0; B2RTV4; Q99744; Q9UMR6;
DE   RecName: Full=Hepatocyte nuclear factor 6;
DE            Short=HNF-6;
DE   AltName: Full=One cut domain family member 1;
DE   AltName: Full=One cut homeobox 1;
GN   Name=ONECUT1; Synonyms=HNF6, HNF6A;
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0002064; P:epithelial cell development; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
//
ID   HNMT_HUMAN              Reviewed;         292 AA.
AC   P50135; B2R9J3; Q546Z6; Q7Z7I2; Q8IU56; Q8WW98; Q9BRW6;
DE   RecName: Full=Histamine N-methyltransferase;
DE            Short=HMT;
DE            EC=2.1.1.8;
GN   Name=HNMT;
DR   GO; GO:0046539; F:histamine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0002347; P:response to tumor cell; IEA:Ensembl.
//
ID   HNRDL_HUMAN             Reviewed;         420 AA.
AC   O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like;
DE            Short=hnRNP D-like;
DE            Short=hnRNP DL;
DE   AltName: Full=AU-rich element RNA-binding factor;
DE   AltName: Full=JKT41-binding protein;
DE   AltName: Full=Protein laAUF1;
GN   Name=HNRNPDL; Synonyms=HNRPDL, JKTBP;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0034046; F:poly(G) binding; IDA:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HNRCL_HUMAN             Reviewed;         293 AA.
AC   O60812; B2RP44;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein C-like 1;
DE            Short=hnRNP C-like-1;
DE   AltName: Full=hnRNP core protein C-like 1;
GN   Name=HNRNPCL1; Synonyms=HNRPCL1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   HNRH1_HUMAN             Reviewed;         449 AA.
AC   P31943; B3KW86; D3DWQ2; Q6IBM4;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein H;
DE            Short=hnRNP H;
DE   Contains:
DE     RecName: Full=Heterogeneous nuclear ribonucleoprotein H, N-terminally processed;
GN   Name=HNRNPH1; Synonyms=HNRPH, HNRPH1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRH2_HUMAN             Reviewed;         449 AA.
AC   P55795; A1L400; Q9HHA7;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein H2;
DE            Short=hnRNP H2;
DE   AltName: Full=FTP-3;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein H';
DE            Short=hnRNP H';
DE   Contains:
DE     RecName: Full=Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed;
GN   Name=HNRNPH2; Synonyms=FTP3, HNRPH2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRH3_HUMAN             Reviewed;         346 AA.
AC   P31942; A8K682; B3KRE1; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4;
AC   Q9UFU4; Q9Y4J5;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein H3;
DE            Short=hnRNP H3;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein 2H9;
DE            Short=hnRNP 2H9;
GN   Name=HNRNPH3; Synonyms=HNRPH3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; NAS:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   HNRL1_HUMAN             Reviewed;         856 AA.
AC   Q9BUJ2; B3KMW7; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9HAL3;
AC   Q9UG75;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1;
DE   AltName: Full=Adenovirus early region 1B-associated protein 5;
DE   AltName: Full=E1B-55 kDa-associated protein 5;
DE            Short=E1B-AP5;
GN   Name=HNRNPUL1; Synonyms=E1BAP5, HNRPUL1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HNRL2_HUMAN             Reviewed;         747 AA.
AC   Q1KMD3; Q8N3B3;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 2;
DE   AltName: Full=Scaffold-attachment factor A2;
DE            Short=SAF-A2;
GN   Name=HNRNPUL2; Synonyms=HNRPUL2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   HNRLL_HUMAN             Reviewed;         542 AA.
AC   Q8WVV9; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q96HR5;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein L-like;
DE            Short=hnRNPLL;
DE   AltName: Full=Stromal RNA-regulating factor;
GN   Name=HNRNPLL; Synonyms=HNRPLL, SRRF; ORFNames=BLOCK24;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   GO; GO:0033120; P:positive regulation of RNA splicing; IDA:UniProtKB.
//
ID   HNRPC_HUMAN             Reviewed;         306 AA.
AC   P07910; D3DS19; D3DS22; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8;
AC   Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3;
DE   RecName: Full=Heterogeneous nuclear ribonucleoproteins C1/C2;
DE            Short=hnRNP C1/C2;
GN   Name=HNRNPC; Synonyms=HNRPC;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProt.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IDA:UniProt.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:HGNC.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IMP:UniProt.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRPD_HUMAN             Reviewed;         355 AA.
AC   Q14103; A8K9J2; P07029; Q01858; Q14100; Q14101; Q14102; Q4W5A1;
AC   Q9UCE8; Q9UCE9;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein D0;
DE            Short=hnRNP D0;
DE   AltName: Full=AU-rich element RNA-binding protein 1;
GN   Name=HNRNPD; Synonyms=AUF1, HNRPD;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HNRPF_HUMAN             Reviewed;         415 AA.
AC   P52597; B3KM84; Q5T0N2; Q96AU2;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein F;
DE            Short=hnRNP F;
DE   AltName: Full=Nucleolin-like protein mcs94-1;
DE   Contains:
DE     RecName: Full=Heterogeneous nuclear ribonucleoprotein F, N-terminally processed;
GN   Name=HNRNPF; Synonyms=HNRPF;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRPK_HUMAN             Reviewed;         463 AA.
AC   P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q922Y7; Q96J62;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein K;
DE            Short=hnRNP K;
DE   AltName: Full=Transformation up-regulated nuclear protein;
DE            Short=TUNP;
GN   Name=HNRNPK; Synonyms=HNRPK;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IMP:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0045716; P:positive regulation of low-density lipoprotein particle receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0072369; P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0010988; P:regulation of low-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HNRPM_HUMAN             Reviewed;         730 AA.
AC   P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein M;
DE            Short=hnRNP M;
GN   Name=HNRNPM; Synonyms=HNRPM, NAGR1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:HGNC.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IMP:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRPL_HUMAN             Reviewed;         589 AA.
AC   P14866; A6ND69; A6NIT8; Q9H3P3;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein L;
DE            Short=hnRNP L;
GN   Name=HNRNPL; Synonyms=HNRPL; ORFNames=P/OKcl.14;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRPQ_HUMAN             Reviewed;         623 AA.
AC   O60506; E1P501; E1P502; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599;
AC   Q96LC1; Q96LC2; Q9Y583;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein Q;
DE            Short=hnRNP Q;
DE   AltName: Full=Glycine- and tyrosine-rich RNA-binding protein;
DE            Short=GRY-RBP;
DE   AltName: Full=NS1-associated protein 1;
DE   AltName: Full=Synaptotagmin-binding, cytoplasmic RNA-interacting protein;
GN   Name=SYNCRIP; Synonyms=HNRPQ, NSAP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0070934; P:CRD-mediated mRNA stabilization; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HNRPR_HUMAN             Reviewed;         633 AA.
AC   O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein R;
DE            Short=hnRNP R;
GN   Name=HNRNPR; Synonyms=HNRPR;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; NAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HNRPU_HUMAN             Reviewed;         825 AA.
AC   Q00839; O75507; Q8N174; Q96HY9; Q9BQ09;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein U;
DE            Short=hnRNP U;
DE   AltName: Full=Scaffold attachment factor A;
DE            Short=SAF-A;
DE   AltName: Full=p120;
DE   AltName: Full=pp120;
GN   Name=HNRNPU; Synonyms=HNRPU, SAFA, U21.1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0070934; P:CRD-mediated mRNA stabilization; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   HOGA1_HUMAN             Reviewed;         327 AA.
AC   Q86XE5; A8K075; Q5T680; Q5T684; Q711P0; Q8N9F2; Q96EV5;
DE   RecName: Full=4-hydroxy-2-oxoglutarate aldolase, mitochondrial;
DE            EC=4.1.3.16;
DE   AltName: Full=Dihydrodipicolinate synthase-like;
DE            Short=DHDPS-like protein;
DE   AltName: Full=Probable 2-keto-4-hydroxyglutarate aldolase;
DE            Short=Probable KHG-aldolase;
DE   AltName: Full=Protein 569272;
DE   Flags: Precursor;
GN   Name=HOGA1; Synonyms=C10orf65, DHDPSL;
DR   GO; GO:0008700; F:4-hydroxy-2-oxoglutarate aldolase activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0019470; P:4-hydroxyproline catabolic process; IDA:BHF-UCL.
DR   GO; GO:0009436; P:glyoxylate catabolic process; IMP:UniProtKB.
DR   GO; GO:0046487; P:glyoxylate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0033609; P:oxalate metabolic process; IMP:BHF-UCL.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IDA:BHF-UCL.
//
ID   HOIL1_HUMAN             Reviewed;         510 AA.
AC   Q9BYM8; O95623; Q86SL2; Q96BS3; Q9BYM9;
DE   RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1;
DE            EC=6.3.2.-;
DE   AltName: Full=HBV-associated factor 4;
DE   AltName: Full=Heme-oxidized IRP2 ubiquitin ligase 1;
DE            Short=HOIL-1;
DE   AltName: Full=Hepatitis B virus X-associated protein 4;
DE   AltName: Full=RING finger protein 54;
DE   AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 3;
GN   Name=RBCK1; Synonyms=C20orf18, RNF54, UBCE7IP3, XAP3, XAP4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HOME1_HUMAN             Reviewed;         354 AA.
AC   Q86YM7; B2R688; O96003; Q86YM5;
DE   RecName: Full=Homer protein homolog 1;
DE            Short=Homer-1;
GN   Name=HOMER1; Synonyms=SYN47;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0035591; F:signaling adaptor activity; IC:BHF-UCL.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0048875; P:chemical homeostasis within a tissue; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0007206; P:phospholipase C-activating G-protein coupled glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IC:BHF-UCL.
DR   GO; GO:0035418; P:protein localization to synapse; IEA:Ensembl.
DR   GO; GO:0090279; P:regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:2001257; P:regulation of cation channel activity; TAS:BHF-UCL.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; TAS:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0003009; P:skeletal muscle contraction; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   HOME2_HUMAN             Reviewed;         354 AA.
AC   Q9NSB8; O95269; O95349; Q9NSB6; Q9NSB7; Q9UNT7;
DE   RecName: Full=Homer protein homolog 2;
DE            Short=Homer-2;
DE   AltName: Full=Cupidin;
GN   Name=HOMER2;
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IEA:Ensembl.
DR   GO; GO:0048875; P:chemical homeostasis within a tissue; IEA:Ensembl.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
//
ID   HOME3_HUMAN             Reviewed;         361 AA.
AC   Q9NSC5; E9PCW9; O14580; O95350; Q9NSB9; Q9NSC0; Q9NSC1;
DE   RecName: Full=Homer protein homolog 3;
DE            Short=Homer-3;
GN   Name=HOMER3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006605; P:protein targeting; TAS:UniProtKB.
//
ID   HOMEZ_HUMAN             Reviewed;         550 AA.
AC   Q8IX15; A1L445; B4DZ80; F8WCA3; Q6P049; Q86XB6; Q9P2A5;
DE   RecName: Full=Homeobox and leucine zipper protein Homez;
DE   AltName: Full=Homeodomain leucine zipper-containing factor;
GN   Name=HOMEZ; Synonyms=KIAA1443;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HOOK1_HUMAN             Reviewed;         728 AA.
AC   Q9UJC3; A8K8E9; O60561; Q5TG44;
DE   RecName: Full=Protein Hook homolog 1;
DE            Short=h-hook1;
DE            Short=hHK1;
GN   Name=HOOK1;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   HOOK3_HUMAN             Reviewed;         718 AA.
AC   Q86VS8; D3DSY8; Q8NBH0; Q9BY13;
DE   RecName: Full=Protein Hook homolog 3;
DE            Short=h-hook3;
DE            Short=hHK3;
GN   Name=HOOK3;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IMP:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0051645; P:Golgi localization; IMP:UniProtKB.
DR   GO; GO:0022027; P:interkinetic nuclear migration; ISS:BHF-UCL.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0034454; P:microtubule anchoring at centrosome; ISS:BHF-UCL.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:BHF-UCL.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0071539; P:protein localization to centrosome; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   HOOK2_HUMAN             Reviewed;         719 AA.
AC   Q96ED9; O60562;
DE   RecName: Full=Protein Hook homolog 2;
DE            Short=h-hook2;
DE            Short=hHK2;
GN   Name=HOOK2;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   HOP2_HUMAN              Reviewed;         217 AA.
AC   Q9P2W1; C5ILB7; Q14458; Q8WXG2; Q96HA2;
DE   RecName: Full=Homologous-pairing protein 2 homolog;
DE   AltName: Full=Nuclear receptor coactivator GT198;
DE   AltName: Full=PSMC3-interacting protein;
DE   AltName: Full=Proteasome 26S ATPase subunit 3-interacting protein;
DE   AltName: Full=Tat-binding protein 1-interacting protein;
DE            Short=TBP-1-interacting protein;
GN   Name=PSMC3IP; Synonyms=HOP2, TBPIP;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IMP:GOC.
//
ID   HOP_HUMAN               Reviewed;          73 AA.
AC   Q9BPY8; A8K0Z2; E9PB55; G3V294; Q8N0V6; Q96CI1;
DE   RecName: Full=Homeodomain-only protein;
DE   AltName: Full=Lung cancer-associated Y protein;
DE   AltName: Full=Not expressed in choriocarcinoma protein 1;
DE   AltName: Full=Odd homeobox protein 1;
GN   Name=HOPX; Synonyms=HOD, HOP, LAGY, NECC1, OB1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0016575; P:histone deacetylation; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IDA:MGI.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043415; P:positive regulation of skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0051155; P:positive regulation of striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IDA:MGI.
//
ID   HORM1_HUMAN             Reviewed;         394 AA.
AC   Q86X24; A6NMK2; B3KUK1; Q4G114; Q5T5I3; Q5T5I4; Q5T5I5; Q6FIC1;
AC   Q9H0K8;
DE   RecName: Full=HORMA domain-containing protein 1;
DE   AltName: Full=Cancer/testis antigen 46;
DE            Short=CT46;
DE   AltName: Full=Newborn ovary HORMA protein;
GN   Name=HORMAD1; Synonyms=NOHMA;
DR   GO; GO:0001824; P:blastocyst development; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; ISS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0051598; P:meiotic recombination checkpoint; ISS:UniProtKB.
DR   GO; GO:0051177; P:meiotic sister chromatid cohesion; ISS:UniProtKB.
DR   GO; GO:0048477; P:oogenesis; ISS:UniProtKB.
DR   GO; GO:0060629; P:regulation of homologous chromosome segregation; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
//
ID   HORM2_HUMAN             Reviewed;         307 AA.
AC   Q8N7B1; B5MEB2; Q8NHR2;
DE   RecName: Full=HORMA domain-containing protein 2;
GN   Name=HORMAD2;
DR   GO; GO:0007126; P:meiotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0051177; P:meiotic sister chromatid cohesion; ISS:UniProtKB.
//
ID   HORN_HUMAN              Reviewed;        2850 AA.
AC   Q86YZ3; Q5DT20; Q5U1F4;
DE   RecName: Full=Hornerin;
GN   Name=HRNR; Synonyms=S100A18;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0061436; P:establishment of skin barrier; IEP:UniProt.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   HOT_HUMAN               Reviewed;         467 AA.
AC   Q8IWW8; B4DTJ8; Q49A19; Q68CI7; Q6P2B6; Q96MF9;
DE   RecName: Full=Hydroxyacid-oxoacid transhydrogenase, mitochondrial;
DE            Short=HOT;
DE            EC=1.1.99.24;
DE   AltName: Full=Alcohol dehydrogenase iron-containing protein 1;
DE            Short=ADHFe1;
DE   AltName: Full=Fe-containing alcohol dehydrogenase;
DE   Flags: Precursor;
GN   Name=ADHFE1; ORFNames=HMFT2263;
DR   GO; GO:0047988; F:hydroxyacid-oxoacid transhydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0015993; P:molecular hydrogen transport; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HP1B3_HUMAN             Reviewed;         553 AA.
AC   Q5SSJ5; A6NI71; A8K5D7; B3KMZ8; B4E210; Q05BI0; Q5SSJ6; Q5SWC6;
AC   Q6PIM9; Q8NDF0; Q9UHY0;
DE   RecName: Full=Heterochromatin protein 1-binding protein 3;
DE   AltName: Full=Protein HP1-BP74;
GN   Name=HP1BP3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   HPBP1_HUMAN             Reviewed;         362 AA.
AC   Q9NZL4; B3KQP0; B4DG11; O95351; Q6ZNU5;
DE   RecName: Full=Hsp70-binding protein 1;
DE            Short=HspBP1;
DE   AltName: Full=Heat shock protein-binding protein 1;
DE   AltName: Full=Hsp70-binding protein 2;
DE            Short=HspBP2;
DE   AltName: Full=Hsp70-interacting protein 1;
DE   AltName: Full=Hsp70-interacting protein 2;
GN   Name=HSPBP1; Synonyms=HSPBP; ORFNames=PP1845;
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
//
ID   HPCA_HUMAN              Reviewed;         193 AA.
AC   P84074; B2R9T3; D3DPQ7; P32076; P41211; P70510;
DE   RecName: Full=Neuron-specific calcium-binding protein hippocalcin;
DE   AltName: Full=Calcium-binding protein BDR-2;
GN   Name=HPCA; Synonyms=BDR2;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
//
ID   HPCL1_HUMAN             Reviewed;         193 AA.
AC   P37235; Q969S5;
DE   RecName: Full=Hippocalcin-like protein 1;
DE   AltName: Full=Calcium-binding protein BDR-1;
DE   AltName: Full=HLP2;
DE   AltName: Full=Visinin-like protein 3;
DE            Short=VILIP-3;
GN   Name=HPCAL1; Synonyms=BDR1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
//
ID   HPCL4_HUMAN             Reviewed;         191 AA.
AC   Q9UM19; B2R5U2; D3DPU1; Q5TG97; Q8N611;
DE   RecName: Full=Hippocalcin-like protein 4;
DE            Short=HLP4;
GN   Name=HPCAL4;
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
//
ID   HPDL_HUMAN              Reviewed;         371 AA.
AC   Q96IR7; B2R9B0;
DE   RecName: Full=4-hydroxyphenylpyruvate dioxygenase-like protein;
DE            EC=1.13.-.-;
DE   AltName: Full=Glyoxalase domain-containing protein 1;
GN   Name=HPDL; Synonyms=GLOXD1;
DR   GO; GO:0003868; F:4-hydroxyphenylpyruvate dioxygenase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009072; P:aromatic amino acid family metabolic process; IEA:InterPro.
//
ID   HPGDS_HUMAN             Reviewed;         199 AA.
AC   O60760; Q6FHT9;
DE   RecName: Full=Hematopoietic prostaglandin D synthase;
DE            Short=H-PGDS;
DE            EC=5.3.99.2;
DE   AltName: Full=GST class-sigma;
DE   AltName: Full=Glutathione S-transferase;
DE            EC=2.5.1.18;
DE   AltName: Full=Glutathione-dependent PGD synthase;
DE   AltName: Full=Glutathione-requiring prostaglandin D synthase;
DE   AltName: Full=Prostaglandin-H2 D-isomerase;
GN   Name=HPGDS; Synonyms=GSTS, PGDS, PTGDS2;
DR   GuidetoPHARMACOLOGY; 1381; -.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0004364; F:glutathione transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004667; F:prostaglandin-D synthase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0007626; P:locomotory behavior; TAS:ProtInc.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   HPHL1_HUMAN             Reviewed;        1159 AA.
AC   Q6MZM0; Q3C1W7;
DE   RecName: Full=Hephaestin-like protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=HEPHL1;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0004322; F:ferroxidase activity; IDA:MGI.
DR   GO; GO:0006825; P:copper ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IC:MGI.
//
ID   HPIP_HUMAN              Reviewed;         138 AA.
AC   Q9NWW0; D3DUA7; Q68EN7;
DE   RecName: Full=Host cell factor C1 regulator 1;
DE   AltName: Full=HCF-1 beta-propeller-interacting protein;
GN   Name=HCFC1R1; Synonyms=HPIP;
//
ID   HPLN1_HUMAN             Reviewed;         354 AA.
AC   P10915; B2R9A9;
DE   RecName: Full=Hyaluronan and proteoglycan link protein 1;
DE   AltName: Full=Cartilage-linking protein 1;
DE            Short=Cartilage-link protein;
DE   AltName: Full=Proteoglycan link protein;
DE   Flags: Precursor;
GN   Name=HAPLN1; Synonyms=CRTL1;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   HPLN2_HUMAN             Reviewed;         340 AA.
AC   Q9GZV7; Q5T3J0;
DE   RecName: Full=Hyaluronan and proteoglycan link protein 2;
DE   AltName: Full=Brain link protein 1;
DE   Flags: Precursor;
GN   Name=HAPLN2; Synonyms=BRAL1;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   HPLN3_HUMAN             Reviewed;         360 AA.
AC   Q96S86; A8K7P0;
DE   RecName: Full=Hyaluronan and proteoglycan link protein 3;
DE   Flags: Precursor;
GN   Name=HAPLN3; Synonyms=EXLD1; ORFNames=UNQ238/PRO271;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   HPLN4_HUMAN             Reviewed;         402 AA.
AC   Q86UW8; A5PKW5; Q96PW2;
DE   RecName: Full=Hyaluronan and proteoglycan link protein 4;
DE   AltName: Full=Brain link protein 2;
DE   Flags: Precursor;
GN   Name=HAPLN4; Synonyms=BRAL2, KIAA1926;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   HPPD_HUMAN              Reviewed;         393 AA.
AC   P32754; A8K461; B3KQ63; Q13234;
DE   RecName: Full=4-hydroxyphenylpyruvate dioxygenase;
DE            EC=1.13.11.27;
DE   AltName: Full=4-hydroxyphenylpyruvic acid oxidase;
DE            Short=4HPPD;
DE            Short=HPD;
DE            Short=HPPDase;
GN   Name=HPD; Synonyms=PPD;
DR   GO; GO:0003868; F:4-hydroxyphenylpyruvate dioxygenase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006572; P:tyrosine catabolic process; ISS:UniProtKB.
//
ID   HPRT_HUMAN              Reviewed;         218 AA.
AC   P00492; A6NHF0; B2R8M9;
DE   RecName: Full=Hypoxanthine-guanine phosphoribosyltransferase;
DE            Short=HGPRT;
DE            Short=HGPRTase;
DE            EC=2.4.2.8;
GN   Name=HPRT1; Synonyms=HPRT;
DR   GO; GO:0052657; F:guanine phosphoribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004422; F:hypoxanthine phosphoribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006168; P:adenine salvage; IBA:RefGenome.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0019835; P:cytolysis; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0042417; P:dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0046038; P:GMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0032263; P:GMP salvage; IBA:RefGenome.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0006178; P:guanine salvage; IDA:UniProtKB.
DR   GO; GO:0046100; P:hypoxanthine metabolic process; IMP:UniProtKB.
DR   GO; GO:0043103; P:hypoxanthine salvage; IDA:UniProtKB.
DR   GO; GO:0046040; P:IMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0032264; P:IMP salvage; IBA:RefGenome.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0046651; P:lymphocyte proliferation; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0045964; P:positive regulation of dopamine metabolic process; IMP:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IMP:UniProtKB.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
//
ID   HPS1_HUMAN              Reviewed;         700 AA.
AC   Q92902; A8MRT2; O15402; O15502; Q5TAA3; Q8WXE5;
DE   RecName: Full=Hermansky-Pudlak syndrome 1 protein;
GN   Name=HPS1; Synonyms=HPS;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0048069; P:eye pigmentation; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; TAS:ProtInc.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0033299; P:secretion of lysosomal enzymes; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   HPS4_HUMAN              Reviewed;         708 AA.
AC   Q9NQG7; B1AHQ4; Q5H8V6; Q96LX6; Q9BY93; Q9UH37; Q9UH38;
DE   RecName: Full=Hermansky-Pudlak syndrome 4 protein;
DE   AltName: Full=Light-ear protein homolog;
GN   Name=HPS4; Synonyms=KIAA1667;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0007599; P:hemostasis; TAS:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IDA:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048075; P:positive regulation of eye pigmentation; TAS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IPI:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IDA:UniProtKB.
//
ID   HPS3_HUMAN              Reviewed;        1004 AA.
AC   Q969F9; A8K6G6; Q8WTV6; Q96AP1; Q96MR3; Q9H608;
DE   RecName: Full=Hermansky-Pudlak syndrome 3 protein;
GN   Name=HPS3;
DR   GO; GO:0006996; P:organelle organization; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
//
ID   HPS5_HUMAN              Reviewed;        1129 AA.
AC   Q9UPZ3; A8K6J8; A8K8S1; D3DQX9; D3DQY0; O95942; Q8N4U0;
DE   RecName: Full=Hermansky-Pudlak syndrome 5 protein;
DE   AltName: Full=Alpha-integrin-binding protein 63;
DE   AltName: Full=Ruby-eye protein 2 homolog;
DE            Short=Ru2;
GN   Name=HPS5; Synonyms=AIBP63, KIAA1017;
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0006996; P:organelle organization; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
//
ID   HPS6_HUMAN              Reviewed;         775 AA.
AC   Q86YV9; Q5VV69; Q9H685;
DE   RecName: Full=Hermansky-Pudlak syndrome 6 protein;
DE   AltName: Full=Ruby-eye protein homolog;
DE            Short=Ru;
GN   Name=HPS6;
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006996; P:organelle organization; IEA:Ensembl.
//
ID   HPSE2_HUMAN             Reviewed;         592 AA.
AC   Q8WWQ2; Q5VUH4; Q5VUH5; Q5VUH6; Q8WWQ1; Q9HB37; Q9HB38; Q9HB39;
DE   RecName: Full=Inactive heparanase-2;
DE            Short=Hpa2;
DE   Flags: Precursor;
GN   Name=HPSE2; Synonyms=HPA2;
DR   GO; GO:0043395; F:heparan sulfate proteoglycan binding; IDA:UniProtKB.
DR   GO; GO:0030305; F:heparanase activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HPSE_HUMAN              Reviewed;         543 AA.
AC   Q9Y251; A9JIG7; C7F7I3; C7F7I4; E9PCA9; E9PGR1; Q53GE5; Q9UL39;
DE   RecName: Full=Heparanase;
DE            EC=3.2.1.166;
DE   AltName: Full=Endo-glucoronidase;
DE   AltName: Full=Heparanase-1;
DE            Short=Hpa1;
DE   Contains:
DE     RecName: Full=Heparanase 8 kDa subunit;
DE   Contains:
DE     RecName: Full=Heparanase 50 kDa subunit;
DE   Flags: Precursor;
GN   Name=HPSE; Synonyms=HEP, HPA, HPA1, HPR1, HPSE1, HSE1;
DR   GO; GO:0004566; F:beta-glucuronidase activity; TAS:ProtInc.
DR   GO; GO:0030305; F:heparanase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0045545; F:syndecan binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030200; P:heparan sulfate proteoglycan catabolic process; IDA:UniProtKB.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IDA:UniProtKB.
DR   GO; GO:0051798; P:positive regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:UniProtKB.
DR   GO; GO:0006029; P:proteoglycan metabolic process; TAS:ProtInc.
DR   GO; GO:0051797; P:regulation of hair follicle development; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0061042; P:vascular wound healing; IEA:Ensembl.
//
ID   HPT_HUMAN               Reviewed;         406 AA.
AC   P00738; B0AZL5; P00737; Q0VAC4; Q0VAC5; Q2PP15; Q3B7J0; Q6LBY9;
AC   Q9UC67;
DE   RecName: Full=Haptoglobin;
DE   AltName: Full=Zonulin;
DE   Contains:
DE     RecName: Full=Haptoglobin alpha chain;
DE   Contains:
DE     RecName: Full=Haptoglobin beta chain;
DE   Flags: Precursor;
GN   Name=HP;
DR   GO; GO:0016209; F:antioxidant activity; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030492; F:hemoglobin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:2000296; P:negative regulation of hydrogen peroxide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:BHF-UCL.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:BHF-UCL.
//
ID   HPTR_HUMAN              Reviewed;         348 AA.
AC   P00739; Q7LE20; Q92658; Q92659; Q9ULB0;
DE   RecName: Full=Haptoglobin-related protein;
DE   Flags: Precursor;
GN   Name=HPR;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030492; F:hemoglobin binding; NAS:UniProtKB.
//
ID   HRC23_HUMAN             Reviewed;        1158 AA.
AC   Q9BVR0;
DE   RecName: Full=Putative HERC2-like protein 3;
GN   Name=HERC2P3;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
//
ID   HRCT1_HUMAN             Reviewed;         115 AA.
AC   Q6UXD1; B7ZBJ1;
DE   RecName: Full=Histidine-rich carboxyl terminus protein 1;
GN   Name=HRCT1; ORFNames=UNQ338/PRO537;
//
ID   HRES1_HUMAN             Reviewed;         223 AA.
AC   P13985;
DE   RecName: Full=Putative HTLV-1-related endogenous sequence;
DE   AltName: Full=p25;
GN   Name=HRES1;
//
ID   HRG1_HUMAN              Reviewed;         146 AA.
AC   Q6P1K1; Q9BUB3; Q9NX17;
DE   RecName: Full=Heme transporter HRG1;
DE   AltName: Full=Heme-responsive gene 1 protein homolog;
DE            Short=HRG-1;
DE            Short=hHRG-1;
DE   AltName: Full=Solute carrier family 48 member 1;
GN   Name=SLC48A1; Synonyms=HRG1;
DR   GO; GO:0015232; F:heme transporter activity; IEA:InterPro.
DR   GO; GO:0015886; P:heme transport; IMP:MGI.
//
ID   HRG_HUMAN               Reviewed;         525 AA.
AC   P04196; B9EK35; D3DNU7;
DE   RecName: Full=Histidine-rich glycoprotein;
DE   AltName: Full=Histidine-proline-rich glycoprotein;
DE            Short=HPRG;
DE   Flags: Precursor;
GN   Name=HRG;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0043395; F:heparan sulfate proteoglycan binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0019865; F:immunoglobulin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; ISS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2001027; P:negative regulation of endothelial cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IEA:Ensembl.
DR   GO; GO:0010593; P:negative regulation of lamellipodium assembly; IDA:UniProtKB.
DR   GO; GO:1900747; P:negative regulation of vascular endothelial growth factor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; IDA:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000504; P:positive regulation of blood vessel remodeling; IDA:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0002839; P:positive regulation of immune response to tumor cell; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0030193; P:regulation of blood coagulation; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010543; P:regulation of platelet activation; ISS:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IDA:UniProtKB.
//
ID   HRH1_HUMAN              Reviewed;         487 AA.
AC   P35367; A8K047; Q6P9E5;
DE   RecName: Full=Histamine H1 receptor;
DE            Short=H1R;
DE            Short=HH1R;
GN   Name=HRH1;
DR   GuidetoPHARMACOLOGY; 262; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004969; F:histamine receptor activity; ISS:BHF-UCL.
DR   GO; GO:0071420; P:cellular response to histamine; ISS:BHF-UCL.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; ISS:BHF-UCL.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0043114; P:regulation of vascular permeability; IEA:InterPro.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   HRH2_HUMAN              Reviewed;         359 AA.
AC   P25021; B5BUP7; Q14464; Q7Z5R9;
DE   RecName: Full=Histamine H2 receptor;
DE            Short=H2R;
DE            Short=HH2R;
DE   AltName: Full=Gastric receptor I;
GN   Name=HRH2;
DR   GuidetoPHARMACOLOGY; 263; -.
DR   GO; GO:0004969; F:histamine receptor activity; TAS:ProtInc.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0001698; P:gastrin-induced gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0048732; P:gland development; IEA:Ensembl.
DR   GO; GO:0001697; P:histamine-induced gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:InterPro.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   HRH3_HUMAN              Reviewed;         445 AA.
AC   Q9Y5N1; Q4QRI7; Q9GZX2; Q9H4K8;
DE   RecName: Full=Histamine H3 receptor;
DE            Short=H3R;
DE            Short=HH3R;
DE   AltName: Full=G-protein coupled receptor 97;
GN   Name=HRH3; Synonyms=GPCR97;
DR   GuidetoPHARMACOLOGY; 264; -.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004969; F:histamine receptor activity; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0042756; P:drinking behavior; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0014053; P:negative regulation of gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0014063; P:negative regulation of serotonin secretion; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0014061; P:regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
//
ID   HRH4_HUMAN              Reviewed;         390 AA.
AC   Q9H3N8; B0YJ19; B2KJ48; Q4G0I6; Q9GZQ0;
DE   RecName: Full=Histamine H4 receptor;
DE            Short=H4R;
DE            Short=HH4R;
DE   AltName: Full=AXOR35;
DE   AltName: Full=G-protein coupled receptor 105;
DE   AltName: Full=GPRv53;
DE   AltName: Full=Pfi-013;
DE   AltName: Full=SP9144;
GN   Name=HRH4; Synonyms=GPCR105;
DR   GuidetoPHARMACOLOGY; 265; -.
DR   GO; GO:0004969; F:histamine receptor activity; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:InterPro.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:InterPro.
//
ID   HRK_HUMAN               Reviewed;          91 AA.
AC   O00198;
DE   RecName: Full=Activator of apoptosis harakiri;
DE   AltName: Full=BH3-interacting domain-containing protein 3;
DE   AltName: Full=Neuronal death protein DP5;
GN   Name=HRK; Synonyms=BID3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.
//
ID   HRSL3_HUMAN             Reviewed;         162 AA.
AC   P53816; B2R7Q4; B7XAK5; Q3SYI3; Q9HDD1;
DE   RecName: Full=HRAS-like suppressor 3;
DE            Short=HRSL3;
DE            EC=3.1.1.32;
DE            EC=3.1.1.4;
DE   AltName: Full=Adipose-specific phospholipase A2;
DE            Short=AdPLA;
DE   AltName: Full=Group XVI phospholipase A1/A2;
DE   AltName: Full=H-rev 107 protein homolog;
DE   AltName: Full=HRAS-like suppressor 1;
DE   AltName: Full=HREV107-1;
DE   AltName: Full=HREV107-3;
DE   AltName: Full=Renal carcinoma antigen NY-REN-65;
GN   Name=PLA2G16; Synonyms=HRASLS3, HREV107;
DR   GO; GO:0052740; F:1-acyl-2-lysophosphatidylserine acylhydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008970; F:phosphatidylcholine 1-acylhydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052739; F:phosphatidylserine 1-acylhydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HRSL2_HUMAN             Reviewed;         162 AA.
AC   Q9NWW9; B9A7L8;
DE   RecName: Full=HRAS-like suppressor 2;
DE            EC=2.3.1.-;
DE            EC=3.1.1.-;
GN   Name=HRASLS2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   HRSL4_HUMAN             Reviewed;         164 AA.
AC   Q9UL19; B2R599; B4DDW2; E7ENZ7; O95200;
DE   RecName: Full=Retinoic acid receptor responder protein 3;
DE            EC=3.1.1.-;
DE   AltName: Full=HRAS-like suppressor 4;
DE            Short=HRSL4;
DE   AltName: Full=RAR-responsive protein TIG3;
DE   AltName: Full=Retinoid-inducible gene 1 protein;
DE   AltName: Full=Tazarotene-induced gene 3 protein;
GN   Name=RARRES3; Synonyms=RIG1, TIG3;
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006644; P:phospholipid metabolic process; IDA:UniProtKB.
//
ID   HRSL5_HUMAN             Reviewed;         279 AA.
AC   Q96KN8; B7X6T1; F5GZ87; F5H4Y9;
DE   RecName: Full=Ca(2+)-independent N-acyltransferase;
DE            Short=iNAT;
DE            EC=2.3.1.-;
DE   AltName: Full=H-rev107-like protein 5;
DE   AltName: Full=HRAS-like suppressor 5;
DE            Short=HRSL5;
GN   Name=HRASLS5; Synonyms=HRLP5;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
//
ID   HRSL1_HUMAN             Reviewed;         168 AA.
AC   Q9HDD0; D2KX19;
DE   RecName: Full=Phospholipid-metabolizing enzyme A-C1;
DE            EC=2.3.1.-;
DE            EC=3.1.1.-;
DE   AltName: Full=HRAS-like suppressor 1;
DE            Short=HRSL1;
GN   Name=HRASLS;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   HS105_HUMAN             Reviewed;         858 AA.
AC   Q92598; B4DYH1; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q9UPC4;
DE   RecName: Full=Heat shock protein 105 kDa;
DE   AltName: Full=Antigen NY-CO-25;
DE   AltName: Full=Heat shock 110 kDa protein;
GN   Name=HSPH1; Synonyms=HSP105, HSP110, KIAA0201;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:Ensembl.
DR   GO; GO:0045345; P:positive regulation of MHC class I biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0051135; P:positive regulation of NK T cell activation; TAS:BHF-UCL.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   HS12B_HUMAN             Reviewed;         686 AA.
AC   Q96MM6; D3DVX7; Q2TAK3; Q9BR52;
DE   RecName: Full=Heat shock 70 kDa protein 12B;
GN   Name=HSPA12B; Synonyms=C20orf60;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   HS12A_HUMAN             Reviewed;         675 AA.
AC   O43301;
DE   RecName: Full=Heat shock 70 kDa protein 12A;
GN   Name=HSPA12A; Synonyms=KIAA0417;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   HS2ST_HUMAN             Reviewed;         356 AA.
AC   Q7LGA3; D3DT22; O75036; Q32NB5; Q8TAC5; Q9H441; Q9NUJ9;
DE   RecName: Full=Heparan sulfate 2-O-sulfotransferase 1;
DE            Short=2-O-sulfotransferase;
DE            Short=2OST;
DE            EC=2.8.2.-;
GN   Name=HS2ST1; Synonyms=HS2ST, KIAA0448;
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS3S1_HUMAN             Reviewed;         307 AA.
AC   O14792; B3KUA6; Q6PEY8;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1;
DE            EC=2.8.2.23;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1;
DE            Short=3-OST-1;
DE            Short=Heparan sulfate 3-O-sulfotransferase 1;
DE            Short=h3-OST-1;
DE   Flags: Precursor;
GN   Name=HS3ST1; Synonyms=3OST, 3OST1;
DR   GO; GO:0008467; F:[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; IEA:UniProtKB-EC.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS3S4_HUMAN             Reviewed;         456 AA.
AC   Q9Y661; Q5QI42; Q8NDC2;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 4;
DE            EC=2.8.2.23;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4;
DE            Short=3-OST-4;
DE            Short=Heparan sulfate 3-O-sulfotransferase 4;
DE            Short=h3-OST-4;
GN   Name=HS3ST4; Synonyms=3OST4;
DR   GO; GO:0008467; F:[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; NAS:UniProtKB.
DR   GO; GO:0030201; P:heparan sulfate proteoglycan metabolic process; NAS:UniProtKB.
//
ID   HS3S2_HUMAN             Reviewed;         367 AA.
AC   Q9Y278; Q52LZ1;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 2;
DE            EC=2.8.2.29;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2;
DE            Short=3-OST-2;
DE            Short=Heparan sulfate 3-O-sulfotransferase 2;
DE            Short=h3-OST-2;
GN   Name=HS3ST2; Synonyms=3OST2; ORFNames=UNQ2442/PRO5004;
DR   GO; GO:0033871; F:[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity; IEA:UniProtKB-EC.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS3S5_HUMAN             Reviewed;         346 AA.
AC   Q8IZT8; A8K1J2; Q52LI2; Q8N285;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 5;
DE            EC=2.8.2.23;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 5;
DE            Short=3-OST-5;
DE            Short=Heparan sulfate 3-O-sulfotransferase 5;
DE            Short=h3-OST-5;
GN   Name=HS3ST5; Synonyms=3OST5, HS3OST5;
DR   GO; GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; NAS:UniProtKB.
DR   GO; GO:0008467; F:[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015015; P:heparan sulfate proteoglycan biosynthetic process, enzymatic modification; IDA:UniProtKB.
DR   GO; GO:0050819; P:negative regulation of coagulation; IDA:UniProtKB.
DR   GO; GO:0006477; P:protein sulfation; IDA:UniProtKB.
DR   GO; GO:0046596; P:regulation of viral entry into host cell; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS3S6_HUMAN             Reviewed;         342 AA.
AC   Q96QI5; Q96RX7;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 6;
DE            EC=2.8.2.23;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6;
DE            Short=3-OST-6;
DE            Short=Heparan sulfate 3-O-sulfotransferase 6;
DE            Short=h3-OST-6;
GN   Name=HS3ST6; Synonyms=HS3ST5;
DR   GO; GO:0008467; F:[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS3SA_HUMAN             Reviewed;         406 AA.
AC   Q9Y663; A8K7N2;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3A1;
DE            EC=2.8.2.30;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1;
DE            Short=3-OST-3A;
DE            Short=Heparan sulfate 3-O-sulfotransferase 3A1;
DE            Short=h3-OST-3A;
GN   Name=HS3ST3A1; Synonyms=3OST3A1, HS3ST3A; ORFNames=UNQ2551/PRO6180;
DR   GO; GO:0033872; F:[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity; IEA:UniProtKB-EC.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS3SB_HUMAN             Reviewed;         390 AA.
AC   Q9Y662; B3KN58; D3DTS6;
DE   RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3B1;
DE            EC=2.8.2.30;
DE   AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1;
DE            Short=3-OST-3B;
DE            Short=Heparan sulfate 3-O-sulfotransferase 3B1;
DE            Short=h3-OST-3B;
GN   Name=HS3ST3B1; Synonyms=3OST3B1, HS3ST3B;
DR   GO; GO:0008467; F:[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; TAS:ProtInc.
DR   GO; GO:0033872; F:[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; TAS:ProtInc.
DR   GO; GO:0015015; P:heparan sulfate proteoglycan biosynthetic process, enzymatic modification; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS71L_HUMAN             Reviewed;         641 AA.
AC   P34931; A6NNB0; B0UXW8; O75634; Q2HXR3; Q8NE72; Q96QC9; Q9UQM1;
DE   RecName: Full=Heat shock 70 kDa protein 1-like;
DE            Short=Heat shock 70 kDa protein 1L;
DE   AltName: Full=Heat shock 70 kDa protein 1-Hom;
DE            Short=HSP70-Hom;
GN   Name=HSPA1L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   HS74L_HUMAN             Reviewed;         839 AA.
AC   O95757; A2ICT2; Q4W5M5; Q8IWA2;
DE   RecName: Full=Heat shock 70 kDa protein 4L;
DE   AltName: Full=Heat shock 70-related protein APG-1;
DE   AltName: Full=Osmotic stress protein 94;
GN   Name=HSPA4L; Synonyms=APG1, OSP94;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; ISS:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
//
ID   HS902_HUMAN             Reviewed;         343 AA.
AC   Q14568;
DE   RecName: Full=Putative heat shock protein HSP 90-alpha A2;
DE   AltName: Full=Heat shock 90 kDa protein 1 alpha-like 3;
GN   Name=HSP90AA2; Synonyms=HSPCAL3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HS905_HUMAN             Reviewed;         334 AA.
AC   Q58FG0;
DE   RecName: Full=Putative heat shock protein HSP 90-alpha A5;
DE   AltName: Full=Heat shock protein 90-alpha E;
DE            Short=Heat shock protein 90Ae;
GN   Name=HSP90AA5P; Synonyms=HSP90AE;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HS904_HUMAN             Reviewed;         418 AA.
AC   Q58FG1;
DE   RecName: Full=Putative heat shock protein HSP 90-alpha A4;
DE   AltName: Full=Heat shock 90 kDa protein 1 alpha-like 2;
DE   AltName: Full=Heat shock protein 90-alpha D;
DE            Short=Heat shock protein 90Ad;
GN   Name=HSP90AA4P; Synonyms=HSP90AD, HSPCAL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HS90A_HUMAN             Reviewed;         732 AA.
AC   P07900; A8K500; B3KPJ9; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5;
DE   RecName: Full=Heat shock protein HSP 90-alpha;
DE   AltName: Full=Heat shock 86 kDa;
DE            Short=HSP 86;
DE            Short=HSP86;
DE   AltName: Full=Lipopolysaccharide-associated protein 2;
DE            Short=LAP-2;
DE            Short=LPS-associated protein 2;
DE   AltName: Full=Renal carcinoma antigen NY-REN-38;
GN   Name=HSP90AA1; Synonyms=HSP90A, HSPC1, HSPCA;
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0030235; F:nitric-oxide synthase regulator activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0030911; F:TPR domain binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006839; P:mitochondrial transport; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0045040; P:protein import into mitochondrial outer membrane; IDA:BHF-UCL.
DR   GO; GO:0042026; P:protein refolding; TAS:UniProtKB.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HS90B_HUMAN             Reviewed;         724 AA.
AC   P08238; B2R5P0; Q5T9W7; Q9NQW0; Q9NTK6;
DE   RecName: Full=Heat shock protein HSP 90-beta;
DE            Short=HSP 90;
DE   AltName: Full=Heat shock 84 kDa;
DE            Short=HSP 84;
DE            Short=HSP84;
GN   Name=HSP90AB1; Synonyms=HSP90B, HSPC2, HSPCB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0002135; F:CTP binding; IEA:Ensembl.
DR   GO; GO:0032564; F:dATP binding; IEA:Ensembl.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0005525; F:GTP binding; IEA:Ensembl.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0030235; F:nitric-oxide synthase regulator activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030911; F:TPR domain binding; ISS:UniProtKB.
DR   GO; GO:0002134; F:UTP binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0045793; P:positive regulation of cell size; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; IMP:MGI.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; IMP:MGI.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
//
ID   HSBP1_HUMAN             Reviewed;          76 AA.
AC   O75506; Q53XA8; Q7Z5Z3;
DE   RecName: Full=Heat shock factor-binding protein 1;
DE   AltName: Full=Nasopharyngeal carcinoma-associated antigen 13;
DE            Short=NPC-A-13;
GN   Name=HSBP1; Synonyms=HSF1BP;
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   HSBPL_HUMAN             Reviewed;          74 AA.
AC   C9JCN9; B2RXG9;
DE   RecName: Full=Heat shock factor-binding protein 1-like protein 1;
GN   Name=HSBP1L1;
//
ID   HSC20_HUMAN             Reviewed;         235 AA.
AC   Q8IWL3; Q9BWS7;
DE   RecName: Full=Iron-sulfur cluster co-chaperone protein HscB, mitochondrial;
DE   AltName: Full=DnaJ homolog subfamily C member 20;
DE   AltName: Full=Hsc20;
DE   Flags: Precursor;
GN   Name=HSCB; Synonyms=DNAJC20, HSC20;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0051259; P:protein oligomerization; IEA:InterPro.
//
ID   HSDL1_HUMAN             Reviewed;         330 AA.
AC   Q3SXM5; B4DSL2; D3DUL4; Q3SXM4; Q8NC98; Q9BY22;
DE   RecName: Full=Inactive hydroxysteroid dehydrogenase-like protein 1;
GN   Name=HSDL1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
//
ID   HSDL2_HUMAN             Reviewed;         418 AA.
AC   Q6YN16; A8K1L4; A8K8X1; A8MSV3; Q658M8; Q9BT58;
DE   RecName: Full=Hydroxysteroid dehydrogenase-like protein 2;
DE            EC=1.-.-.-;
GN   Name=HSDL2; Synonyms=C9orf99;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032934; F:sterol binding; IEA:InterPro.
//
ID   HSF1_HUMAN              Reviewed;         529 AA.
AC   Q00613; A8K4L0; A8MW26; Q53XT4;
DE   RecName: Full=Heat shock factor protein 1;
DE            Short=HSF 1;
DE   AltName: Full=Heat shock transcription factor 1;
DE            Short=HSTF 1;
GN   Name=HSF1; Synonyms=HSTF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001162; F:RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0006952; P:defense response; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0007143; P:female meiotic division; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0090231; P:regulation of spindle checkpoint; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HSF2B_HUMAN             Reviewed;         334 AA.
AC   O75031; B4DX36;
DE   RecName: Full=Heat shock factor 2-binding protein;
GN   Name=HSF2BP;
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   HSF2_HUMAN              Reviewed;         536 AA.
AC   Q03933; B4DGJ4; Q0VAH9; Q2M1K4; Q9H445;
DE   RecName: Full=Heat shock factor protein 2;
DE            Short=HSF 2;
DE   AltName: Full=Heat shock transcription factor 2;
DE            Short=HSTF 2;
GN   Name=HSF2; Synonyms=HSTF2;
DR   GO; GO:0001162; F:RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   HSF4_HUMAN              Reviewed;         492 AA.
AC   Q9ULV5; Q99472; Q9ULV6;
DE   RecName: Full=Heat shock factor protein 4;
DE            Short=HSF 4;
DE            Short=hHSF4;
DE   AltName: Full=Heat shock transcription factor 4;
DE            Short=HSTF 4;
GN   Name=HSF4;
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProt.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HSF5_HUMAN              Reviewed;         596 AA.
AC   Q4G112; Q08EH7; Q8N7V2;
DE   RecName: Full=Heat shock factor protein 5;
DE            Short=HSF 5;
DE   AltName: Full=Heat shock transcription factor 5;
DE            Short=HSTF 5;
GN   Name=HSF5; Synonyms=HSTF5;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HSFX1_HUMAN             Reviewed;         423 AA.
AC   Q9UBD0;
DE   RecName: Full=Heat shock transcription factor, X-linked;
GN   Name=HSFX1; Synonyms=LW-1;
GN   and
GN   Name=HSFX2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HSFY1_HUMAN             Reviewed;         401 AA.
AC   Q96LI6; Q17RC0; Q7Z4L8; Q9BZA2; Q9BZA3;
DE   RecName: Full=Heat shock transcription factor, Y-linked;
DE   AltName: Full=Heat shock transcription factor 2-like protein;
DE            Short=HSF2-like;
GN   Name=HSFY1; Synonyms=HSF2L, HSFY;
GN   and
GN   Name=HSFY2; Synonyms=HSF2L, HSFY;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HSH2D_HUMAN             Reviewed;         352 AA.
AC   Q96JZ2; B5ME72; Q6ZNG7;
DE   RecName: Full=Hematopoietic SH2 domain-containing protein;
DE            Short=Hematopoietic SH2 protein;
DE   AltName: Full=Adaptor in lymphocytes of unknown function X;
GN   Name=HSH2D; Synonyms=ALX;
//
ID   HSP13_HUMAN             Reviewed;         471 AA.
AC   P48723; B2R616; Q8NE40;
DE   RecName: Full=Heat shock 70 kDa protein 13;
DE   AltName: Full=Microsomal stress-70 protein ATPase core;
DE   AltName: Full=Stress-70 protein chaperone microsome-associated 60 kDa protein;
DE   Flags: Precursor;
GN   Name=HSPA13; Synonyms=STCH;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   HSP1_HUMAN              Reviewed;          51 AA.
AC   P04553;
DE   RecName: Full=Sperm protamine P1;
DE   AltName: Full=Cysteine-rich protamine;
GN   Name=PRM1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0006323; P:DNA packaging; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   HSP71_HUMAN             Reviewed;         641 AA.
AC   P08107; B4E3B6; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0;
DE   RecName: Full=Heat shock 70 kDa protein 1A/1B;
DE   AltName: Full=Heat shock 70 kDa protein 1/2;
DE            Short=HSP70-1/HSP70-2;
DE            Short=HSP70.1/HSP70.2;
GN   Name=HSPA1A; Synonyms=HSPA1, HSX70;
GN   and
GN   Name=HSPA1B;
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0016887; F:ATPase activity; IDA:BHF-UCL.
DR   GO; GO:0042623; F:ATPase activity, coupled; IDA:UniProt.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0031072; F:heat shock protein binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044183; F:protein binding involved in protein folding; IDA:BHF-UCL.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070370; P:cellular heat acclimation; IMP:UniProt.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProt.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:UniProt.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0042026; P:protein refolding; IDA:BHF-UCL.
DR   GO; GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   HSP72_HUMAN             Reviewed;         639 AA.
AC   P54652; Q15508; Q53XM3; Q9UE78;
DE   RecName: Full=Heat shock-related 70 kDa protein 2;
DE            Short=Heat shock 70 kDa protein 2;
GN   Name=HSPA2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0051861; F:glycolipid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0007140; P:male meiosis; TAS:ProtInc.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IDA:UniProt.
DR   GO; GO:0031662; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
DR   GO; GO:0007286; P:spermatid development; TAS:ProtInc.
DR   GO; GO:0070194; P:synaptonemal complex disassembly; IEA:Ensembl.
//
ID   HSP74_HUMAN             Reviewed;         840 AA.
AC   P34932; O95756; Q2TAL4;
DE   RecName: Full=Heat shock 70 kDa protein 4;
DE   AltName: Full=HSP70RY;
DE   AltName: Full=Heat shock 70-related protein APG-2;
GN   Name=HSPA4; Synonyms=APG2;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0045040; P:protein import into mitochondrial outer membrane; IDA:BHF-UCL.
DR   GO; GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
//
ID   HSP76_HUMAN             Reviewed;         643 AA.
AC   P17066; Q1HBA8; Q8IYK7; Q9BT95;
DE   RecName: Full=Heat shock 70 kDa protein 6;
DE   AltName: Full=Heat shock 70 kDa protein B';
GN   Name=HSPA6; Synonyms=HSP70B';
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042623; F:ATPase activity, coupled; IDA:UniProt.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProt.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProt.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProt.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   HSP77_HUMAN             Reviewed;         367 AA.
AC   P48741; P19790;
DE   RecName: Full=Putative heat shock 70 kDa protein 7;
DE   AltName: Full=Heat shock 70 kDa protein B;
GN   Name=HSPA7; Synonyms=HSP70B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HSP7C_HUMAN             Reviewed;         646 AA.
AC   P11142; Q9H3R6;
DE   RecName: Full=Heat shock cognate 71 kDa protein;
DE   AltName: Full=Heat shock 70 kDa protein 8;
DE   AltName: Full=Lipopolysaccharide-associated protein 1;
DE            Short=LAP-1;
DE            Short=LPS-associated protein 1;
GN   Name=HSPA8; Synonyms=HSC70, HSP73, HSPA10;
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0016887; F:ATPase activity; IDA:BHF-UCL.
DR   GO; GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0031072; F:heat shock protein binding; IPI:BHF-UCL.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProt.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0042026; P:protein refolding; IDA:UniProt.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HSP7E_HUMAN             Reviewed;         509 AA.
AC   Q0VDF9; A8K8F8; B0YIY9; Q9P0X2; Q9UI07;
DE   RecName: Full=Heat shock 70 kDa protein 14;
DE   AltName: Full=HSP70-like protein 1;
DE   AltName: Full=Heat shock protein HSP60;
GN   Name=HSPA14; Synonyms=HSP60, HSP70L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051083; P:'de novo' cotranslational protein folding; TAS:UniProtKB.
//
ID   HSPB1_HUMAN             Reviewed;         205 AA.
AC   P04792; B2R4N8; Q6FI47; Q96C20; Q96EI7; Q9UC31; Q9UC34; Q9UC35;
AC   Q9UC36;
DE   RecName: Full=Heat shock protein beta-1;
DE            Short=HspB1;
DE   AltName: Full=28 kDa heat shock protein;
DE   AltName: Full=Estrogen-regulated 24 kDa protein;
DE   AltName: Full=Heat shock 27 kDa protein;
DE            Short=HSP 27;
DE   AltName: Full=Stress-responsive protein 27;
DE            Short=SRP27;
GN   Name=HSPB1; Synonyms=HSP27, HSP28;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:BHF-UCL.
DR   GO; GO:0008426; F:protein kinase C inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0043130; F:ubiquitin binding; ISS:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:BHF-UCL.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; ISS:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; ISS:GOC.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0038033; P:positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; ISS:BHF-UCL.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; ISS:BHF-UCL.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0006986; P:response to unfolded protein; NAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   HSPB2_HUMAN             Reviewed;         182 AA.
AC   Q16082; Q6I9U7;
DE   RecName: Full=Heat shock protein beta-2;
DE            Short=HspB2;
DE   AltName: Full=DMPK-binding protein;
DE            Short=MKBP;
GN   Name=HSPB2;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006986; P:response to unfolded protein; NAS:ProtInc.
//
ID   HSPB3_HUMAN             Reviewed;         150 AA.
AC   Q12988;
DE   RecName: Full=Heat shock protein beta-3;
DE            Short=HspB3;
DE   AltName: Full=Heat shock 17 kDa protein;
DE            Short=HSP 17;
DE   AltName: Full=Protein 3;
GN   Name=HSPB3; Synonyms=HSP27, HSPL27;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   HSPB6_HUMAN             Reviewed;         160 AA.
AC   O14558; O14551; Q6NVI3; Q96MG9;
DE   RecName: Full=Heat shock protein beta-6;
DE            Short=HspB6;
DE   AltName: Full=Heat shock 20 kDa-like protein p20;
GN   Name=HSPB6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:InterPro.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HSPB7_HUMAN             Reviewed;         170 AA.
AC   Q9UBY9; B3KQ37; C9K0Y0; Q9NU17;
DE   RecName: Full=Heat shock protein beta-7;
DE            Short=HspB7;
DE   AltName: Full=Cardiovascular heat shock protein;
DE            Short=cvHsp;
GN   Name=HSPB7; Synonyms=CVHSP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   HSPB8_HUMAN             Reviewed;         196 AA.
AC   Q9UJY1; B2R6A6; Q6FIH3; Q9UKS3;
DE   RecName: Full=Heat shock protein beta-8;
DE            Short=HspB8;
DE   AltName: Full=Alpha-crystallin C chain;
DE   AltName: Full=E2-induced gene 1 protein;
DE   AltName: Full=Protein kinase H11;
DE   AltName: Full=Small stress protein-like protein HSP22;
GN   Name=HSPB8; Synonyms=CRYAC, E2IG1, HSP22; ORFNames=PP1629;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HSPB9_HUMAN             Reviewed;         159 AA.
AC   Q9BQS6; B3KSG6; Q52LB4;
DE   RecName: Full=Heat shock protein beta-9;
DE            Short=HspB9;
DE   AltName: Full=Cancer/testis antigen 51;
DE            Short=CT51;
GN   Name=HSPB9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   HTAI2_HUMAN             Reviewed;         242 AA.
AC   Q9BUP3; A8K7S7; D3DQY8; O15383; O60520; O95345; Q53GC1; Q53GG2;
AC   Q6IBI3;
DE   RecName: Full=Oxidoreductase HTATIP2;
DE            EC=1.1.1.-;
DE   AltName: Full=30 kDa HIV-1 TAT-interacting protein;
DE   AltName: Full=HIV-1 TAT-interactive protein 2;
GN   Name=HTATIP2; Synonyms=CC3, TIP30;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0051170; P:nuclear import; IDA:UniProtKB.
DR   GO; GO:0045765; P:regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   HTD2_HUMAN              Reviewed;         168 AA.
AC   P86397;
DE   RecName: Full=Hydroxyacyl-thioester dehydratase type 2, mitochondrial;
DE            Short=HsHTD2;
DE            EC=4.2.1.-;
DE   AltName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase;
DE   Flags: Precursor;
GN   Name=RPP14;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   HTF4_HUMAN              Reviewed;         682 AA.
AC   Q99081; Q7Z3D9; Q86TC1; Q86VM2;
DE   RecName: Full=Transcription factor 12;
DE            Short=TCF-12;
DE   AltName: Full=Class B basic helix-loop-helix protein 20;
DE            Short=bHLHb20;
DE   AltName: Full=DNA-binding protein HTF4;
DE   AltName: Full=E-box-binding protein;
DE   AltName: Full=Transcription factor HTF-4;
GN   Name=TCF12; Synonyms=BHLHB20, HEB, HTF4;
DR   GO; GO:0070888; F:E-box binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HTR5A_HUMAN             Reviewed;        2040 AA.
AC   Q86XA9; Q68DD8; Q6P3S5; Q6P5R9; Q9H8D7; Q9NXB7; Q9P2N0; Q9UFQ3;
DE   RecName: Full=HEAT repeat-containing protein 5A;
GN   Name=HEATR5A; Synonyms=C14orf125, KIAA1316;
//
ID   HTR5B_HUMAN             Reviewed;        2071 AA.
AC   Q9P2D3; B5MDU8; Q7Z3B2; Q9NVL7;
DE   RecName: Full=HEAT repeat-containing protein 5B;
GN   Name=HEATR5B; Synonyms=KIAA1414;
//
ID   HTRA1_HUMAN             Reviewed;         480 AA.
AC   Q92743; D3DRE4; Q9UNS5;
DE   RecName: Full=Serine protease HTRA1;
DE            EC=3.4.21.-;
DE   AltName: Full=High-temperature requirement A serine peptidase 1;
DE   AltName: Full=L56;
DE   AltName: Full=Serine protease 11;
DE   Flags: Precursor;
GN   Name=HTRA1; Synonyms=HTRA, PRSS11;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008236; F:serine-type peptidase activity; ISS:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
//
ID   HTRA2_HUMAN             Reviewed;         458 AA.
AC   O43464; Q9HBZ4; Q9P0Y3; Q9P0Y4;
DE   RecName: Full=Serine protease HTRA2, mitochondrial;
DE            EC=3.4.21.108;
DE   AltName: Full=High temperature requirement protein A2;
DE            Short=HtrA2;
DE   AltName: Full=Omi stress-regulated endoprotease;
DE   AltName: Full=Serine protease 25;
DE   AltName: Full=Serine proteinase OMI;
DE   Flags: Precursor;
GN   Name=HTRA2; Synonyms=OMI, PRSS25;
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IMP:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; IEA:Ensembl.
DR   GO; GO:0097194; P:execution phase of apoptosis; TAS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:ParkinsonsUK-UCL.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0019742; P:pentacyclic triterpenoid metabolic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001269; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IMP:ParkinsonsUK-UCL.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
DR   GO; GO:0016540; P:protein autoprocessing; TAS:ParkinsonsUK-UCL.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
//
ID   HTRA3_HUMAN             Reviewed;         453 AA.
AC   P83110; Q7Z7A2;
DE   RecName: Full=Serine protease HTRA3;
DE            EC=3.4.21.-;
DE   AltName: Full=High-temperature requirement factor A3;
DE   AltName: Full=Pregnancy-related serine protease;
DE   Flags: Precursor;
GN   Name=HTRA3; Synonyms=PRSP;
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
//
ID   HTRA4_HUMAN             Reviewed;         476 AA.
AC   P83105; Q542Z4; Q6PF13;
DE   RecName: Full=Serine protease HTRA4;
DE            EC=3.4.21.-;
DE   AltName: Full=High-temperature requirement factor A4;
DE   Flags: Precursor;
GN   Name=HTRA4;
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:BHF-UCL.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
//
ID   HTSF1_HUMAN             Reviewed;         755 AA.
AC   O43719; D3DWG9; Q59G06; Q99730;
DE   RecName: Full=HIV Tat-specific factor 1;
DE            Short=Tat-SF1;
GN   Name=HTATSF1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
//
ID   HUG1_HUMAN              Reviewed;         362 AA.
AC   O75698;
DE   RecName: Full=Putative uncharacterized protein HUG-1;
DE   AltName: Full=HOX11 upstream gene 1 protein;
GN   Name=HUG1; Synonyms=C10orf1;
//
ID   HUMMR_HUMAN             Reviewed;         240 AA.
AC   Q8TDB4; Q9BZC3;
DE   RecName: Full=Protein MGARP;
DE   AltName: Full=Corneal endothelium-specific protein 1;
DE            Short=CESP-1;
DE   AltName: Full=Hypoxia up-regulated mitochondrial movement regulator protein;
DE   AltName: Full=Mitochondria-localized glutamic acid-rich protein;
DE   AltName: Full=Ovary-specific acidic protein;
GN   Name=MGARP; Synonyms=C4orf49, CESP1, HUMMR, OSAP; ORFNames=GS3582;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0019896; P:axon transport of mitochondrion; ISS:UniProtKB.
DR   GO; GO:0097211; P:cellular response to gonadotropin-releasing hormone; ISS:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; ISS:UniProtKB.
DR   GO; GO:0010822; P:positive regulation of mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; ISS:UniProtKB.
DR   GO; GO:0008090; P:retrograde axon cargo transport; ISS:UniProtKB.
//
ID   HUNIN_HUMAN             Reviewed;          24 AA.
AC   Q8IVG9;
DE   RecName: Full=Putative humanin peptide;
GN   Name=MT-RNR2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048019; F:receptor antagonist activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; NAS:UniProtKB.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; IDA:GOC.
DR   GO; GO:0030595; P:leukocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
//
ID   HUNK_HUMAN              Reviewed;         714 AA.
AC   P57058;
DE   RecName: Full=Hormonally up-regulated neu tumor-associated kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=B19;
DE   AltName: Full=Serine/threonine-protein kinase MAK-V;
GN   Name=HUNK; Synonyms=MAKV;
DR   GuidetoPHARMACOLOGY; 2037; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   HUS1B_HUMAN             Reviewed;         278 AA.
AC   Q8NHY5; Q5T4Z2;
DE   RecName: Full=Checkpoint protein HUS1B;
DE            Short=hHUS1B;
GN   Name=HUS1B;
DR   GO; GO:0000077; P:DNA damage checkpoint; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
//
ID   HUS1_HUMAN              Reviewed;         280 AA.
AC   O60921;
DE   RecName: Full=Checkpoint protein HUS1;
DE            Short=hHUS1;
GN   Name=HUS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IEA:Ensembl.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
//
ID   HUTH_HUMAN              Reviewed;         657 AA.
AC   P42357; B4DQC1; B4E0V8; F5GXF2; F5H1U5; Q4VB92; Q4VB93;
DE   RecName: Full=Histidine ammonia-lyase;
DE            Short=Histidase;
DE            EC=4.3.1.3;
GN   Name=HAL; Synonyms=HIS;
DR   GO; GO:0004397; F:histidine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006548; P:histidine catabolic process; TAS:Reactome.
DR   GO; GO:0019556; P:histidine catabolic process to glutamate and formamide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019557; P:histidine catabolic process to glutamate and formate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HUTI_HUMAN              Reviewed;         426 AA.
AC   Q96NU7; A8K463; Q68CI8;
DE   RecName: Full=Probable imidazolonepropionase;
DE            EC=3.5.2.7;
DE   AltName: Full=Amidohydrolase domain-containing protein 1;
GN   Name=AMDHD1; ORFNames=HMFT1272;
DR   GO; GO:0050480; F:imidazolonepropionase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006548; P:histidine catabolic process; TAS:Reactome.
DR   GO; GO:0019556; P:histidine catabolic process to glutamate and formamide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019557; P:histidine catabolic process to glutamate and formate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HUTU_HUMAN              Reviewed;         676 AA.
AC   Q96N76; E9PE13; Q14C64; Q68CJ7;
DE   RecName: Full=Urocanate hydratase;
DE            Short=Urocanase;
DE            EC=4.2.1.49;
DE   AltName: Full=Imidazolonepropionate hydrolase;
GN   Name=UROC1;
DR   GO; GO:0016153; F:urocanate hydratase activity; IDA:BHF-UCL.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006548; P:histidine catabolic process; IMP:BHF-UCL.
DR   GO; GO:0019556; P:histidine catabolic process to glutamate and formamide; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019557; P:histidine catabolic process to glutamate and formate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HUWE1_HUMAN             Reviewed;        4374 AA.
AC   Q7Z6Z7; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q8NG67; Q9BUI0; Q9HCJ4;
AC   Q9NSL6; Q9P0A9;
DE   RecName: Full=E3 ubiquitin-protein ligase HUWE1;
DE            EC=6.3.2.-;
DE   AltName: Full=ARF-binding protein 1;
DE            Short=ARF-BP1;
DE   AltName: Full=HECT, UBA and WWE domain-containing protein 1;
DE   AltName: Full=Homologous to E6AP carboxyl terminus homologous protein 9;
DE            Short=HectH9;
DE   AltName: Full=Large structure of UREB1;
DE            Short=LASU1;
DE   AltName: Full=Mcl-1 ubiquitin ligase E3;
DE            Short=Mule;
DE   AltName: Full=Upstream regulatory element-binding protein 1;
DE            Short=URE-B1;
DE            Short=URE-binding protein 1;
GN   Name=HUWE1; Synonyms=KIAA0312, KIAA1578, UREB1; ORFNames=HSPC272;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; IMP:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016574; P:histone ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   HV101_HUMAN             Reviewed;         117 AA.
AC   P01742;
DE   RecName: Full=Ig heavy chain V-I region EU;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV102_HUMAN             Reviewed;         117 AA.
AC   P01743;
DE   RecName: Full=Ig heavy chain V-I region HG3;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV103_HUMAN             Reviewed;         117 AA.
AC   P23083;
DE   RecName: Full=Ig heavy chain V-I region V35;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   HV104_HUMAN             Reviewed;         147 AA.
AC   P01744;
DE   RecName: Full=Ig heavy chain V-I region ND;
DE   Flags: Precursor; Fragments;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV105_HUMAN             Reviewed;         124 AA.
AC   P01760;
DE   RecName: Full=Ig heavy chain V-I region WOL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV107_HUMAN             Reviewed;         125 AA.
AC   P06326;
DE   RecName: Full=Ig heavy chain V-I region Mot;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV106_HUMAN             Reviewed;         124 AA.
AC   P01761;
DE   RecName: Full=Ig heavy chain V-I region SIE;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV108_HUMAN             Reviewed;         120 AA.
AC   P80421;
DE   RecName: Full=Ig heavy chain V-I region DOT;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   HV201_HUMAN             Reviewed;         126 AA.
AC   P01814;
DE   RecName: Full=Ig heavy chain V-II region OU;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV202_HUMAN             Reviewed;         120 AA.
AC   P01815;
DE   RecName: Full=Ig heavy chain V-II region COR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV203_HUMAN             Reviewed;         119 AA.
AC   P01816;
DE   RecName: Full=Ig heavy chain V-II region DAW;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV204_HUMAN             Reviewed;         125 AA.
AC   P01817;
DE   RecName: Full=Ig heavy chain V-II region MCE;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV205_HUMAN             Reviewed;         121 AA.
AC   P01818;
DE   RecName: Full=Ig heavy chain V-II region HE;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV207_HUMAN             Reviewed;         117 AA.
AC   P01825;
DE   RecName: Full=Ig heavy chain V-II region NEWM;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV206_HUMAN             Reviewed;         129 AA.
AC   P01824;
DE   RecName: Full=Ig heavy chain V-II region WAH;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV209_HUMAN             Reviewed;         146 AA.
AC   P06331;
DE   RecName: Full=Ig heavy chain V-II region ARH-77;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV208_HUMAN             Reviewed;         147 AA.
AC   P04438;
DE   RecName: Full=Ig heavy chain V-II region SESS;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV305_HUMAN             Reviewed;         120 AA.
AC   P01766;
DE   RecName: Full=Ig heavy chain V-III region BRO;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV302_HUMAN             Reviewed;         114 AA.
AC   P01763;
DE   RecName: Full=Ig heavy chain V-III region WEA;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV301_HUMAN             Reviewed;         122 AA.
AC   P01762;
DE   RecName: Full=Ig heavy chain V-III region TRO;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV307_HUMAN             Reviewed;         122 AA.
AC   P01768;
DE   RecName: Full=Ig heavy chain V-III region CAM;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV303_HUMAN             Reviewed;         117 AA.
AC   P01764;
DE   RecName: Full=Ig heavy chain V-III region VH26;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV306_HUMAN             Reviewed;         115 AA.
AC   P01767;
DE   RecName: Full=Ig heavy chain V-III region BUT;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV308_HUMAN             Reviewed;         122 AA.
AC   P01769;
DE   RecName: Full=Ig heavy chain V-III region GA;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV304_HUMAN             Reviewed;         115 AA.
AC   P01765;
DE   RecName: Full=Ig heavy chain V-III region TIL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV309_HUMAN             Reviewed;         119 AA.
AC   P01770;
DE   RecName: Full=Ig heavy chain V-III region NIE;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV310_HUMAN             Reviewed;         121 AA.
AC   P01771;
DE   RecName: Full=Ig heavy chain V-III region HIL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV312_HUMAN             Reviewed;         119 AA.
AC   P01773;
DE   RecName: Full=Ig heavy chain V-III region BUR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV313_HUMAN             Reviewed;         119 AA.
AC   P01774;
DE   RecName: Full=Ig heavy chain V-III region POM;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV314_HUMAN             Reviewed;         119 AA.
AC   P01775;
DE   RecName: Full=Ig heavy chain V-III region LAY;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV311_HUMAN             Reviewed;         126 AA.
AC   P01772;
DE   RecName: Full=Ig heavy chain V-III region KOL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV315_HUMAN             Reviewed;         117 AA.
AC   P01776;
DE   RecName: Full=Ig heavy chain V-III region WAS;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV316_HUMAN             Reviewed;         119 AA.
AC   P01777;
DE   RecName: Full=Ig heavy chain V-III region TEI;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV318_HUMAN             Reviewed;         116 AA.
AC   P01779;
DE   RecName: Full=Ig heavy chain V-III region TUR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV317_HUMAN             Reviewed;         116 AA.
AC   P01778;
DE   RecName: Full=Ig heavy chain V-III region ZAP;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV321_HUMAN             Reviewed;         120 AA.
AC   P01782;
DE   RecName: Full=Ig heavy chain V-III region DOB;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV319_HUMAN             Reviewed;         115 AA.
AC   P01780;
DE   RecName: Full=Ig heavy chain V-III region JON;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV320_HUMAN             Reviewed;         116 AA.
AC   P01781;
DE   RecName: Full=Ig heavy chain V-III region GAL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   HV322_HUMAN             Reviewed;         118 AA.
AC   P80419;
DE   RecName: Full=Ig heavy chain V-III region GAR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   HVCN1_HUMAN             Reviewed;         273 AA.
AC   Q96D96; A8MQ37; B4DEB3; F8WCH5; Q6UW11; Q96IS5;
DE   RecName: Full=Voltage-gated hydrogen channel 1;
DE   AltName: Full=Hydrogen voltage-gated channel 1;
DE            Short=HV1;
DE   AltName: Full=Voltage sensor domain-only protein;
GN   Name=HVCN1; Synonyms=VSOP; ORFNames=UNQ578/PRO1140;
DR   GuidetoPHARMACOLOGY; 746; -.
DR   GO; GO:0022843; F:voltage-gated cation channel activity; TAS:Reactome.
DR   GO; GO:0030171; F:voltage-gated proton channel activity; IDA:UniProtKB.
DR   GO; GO:0071467; P:cellular response to pH; IDA:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IDA:UniProtKB.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; IDA:UniProtKB.
DR   GO; GO:0009268; P:response to pH; ISS:HGNC.
DR   GO; GO:0010043; P:response to zinc ion; IDA:HGNC.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
//
ID   HXA10_HUMAN             Reviewed;         410 AA.
AC   P31260; O43370; O43605; Q15949; Q504T1;
DE   RecName: Full=Homeobox protein Hox-A10;
DE   AltName: Full=Homeobox protein Hox-1.8;
DE   AltName: Full=Homeobox protein Hox-1H;
DE   AltName: Full=PL;
GN   Name=HOXA10; Synonyms=HOX1H;
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA11_HUMAN             Reviewed;         313 AA.
AC   P31270; A4D190;
DE   RecName: Full=Homeobox protein Hox-A11;
DE   AltName: Full=Homeobox protein Hox-1I;
GN   Name=HOXA11; Synonyms=HOX1I;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048589; P:developmental growth; ISS:UniProtKB.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0007501; P:mesodermal cell fate specification; ISS:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; ISS:UniProtKB.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0010720; P:positive regulation of cell development; ISS:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA13_HUMAN             Reviewed;         388 AA.
AC   P31271; A4D188; O43371;
DE   RecName: Full=Homeobox protein Hox-A13;
DE   AltName: Full=Homeobox protein Hox-1J;
GN   Name=HOXA13; Synonyms=HOX1J;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0060442; P:branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060847; P:endothelial cell fate specification; IEA:Ensembl.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:2001055; P:positive regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030510; P:regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   HXA1_HUMAN              Reviewed;         335 AA.
AC   P49639; A4D184; B2R8U7; O43363;
DE   RecName: Full=Homeobox protein Hox-A1;
DE   AltName: Full=Homeobox protein Hox-1F;
GN   Name=HOXA1; Synonyms=HOX1F;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0021599; P:abducens nerve formation; IMP:DFLAT.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; IMP:DFLAT.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060840; P:artery development; IMP:DFLAT.
DR   GO; GO:0048844; P:artery morphogenesis; IMP:DFLAT.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IMP:DFLAT.
DR   GO; GO:0090103; P:cochlea morphogenesis; IMP:DFLAT.
DR   GO; GO:0050890; P:cognition; IDA:DFLAT.
DR   GO; GO:0048702; P:embryonic neurocranium morphogenesis; IMP:DFLAT.
DR   GO; GO:0021612; P:facial nerve structural organization; IEA:Ensembl.
DR   GO; GO:0021754; P:facial nucleus development; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IMP:DFLAT.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0050905; P:neuromuscular process; IDA:DFLAT.
DR   GO; GO:0007634; P:optokinetic behavior; IDA:DFLAT.
DR   GO; GO:0042473; P:outer ear morphogenesis; IDA:DFLAT.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050795; P:regulation of behavior; IDA:DFLAT.
DR   GO; GO:0021569; P:rhombomere 3 development; IEA:Ensembl.
DR   GO; GO:0021570; P:rhombomere 4 development; IEA:Ensembl.
DR   GO; GO:0021571; P:rhombomere 5 development; IEA:Ensembl.
DR   GO; GO:0060876; P:semicircular canal formation; IMP:DFLAT.
DR   GO; GO:0007605; P:sensory perception of sound; IDA:DFLAT.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA2_HUMAN              Reviewed;         376 AA.
AC   O43364; A1L4K3; B2RMW3;
DE   RecName: Full=Homeobox protein Hox-A2;
DE   AltName: Full=Homeobox protein Hox-1K;
GN   Name=HOXA2; Synonyms=HOX1K;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0035284; P:brain segmentation; IEA:Ensembl.
DR   GO; GO:0001709; P:cell fate determination; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021568; P:rhombomere 2 development; IEA:Ensembl.
DR   GO; GO:0021658; P:rhombomere 3 morphogenesis; IEA:Ensembl.
DR   GO; GO:0007379; P:segment specification; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA3_HUMAN              Reviewed;         443 AA.
AC   O43365; A4D181;
DE   RecName: Full=Homeobox protein Hox-A3;
DE   AltName: Full=Homeobox protein Hox-1E;
GN   Name=HOXA3; Synonyms=HOX1E;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0021615; P:glossopharyngeal nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0048645; P:organ formation; IEA:Ensembl.
DR   GO; GO:0060017; P:parathyroid gland development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010159; P:specification of organ position; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA4_HUMAN              Reviewed;         320 AA.
AC   Q00056; A4D180; O43366;
DE   RecName: Full=Homeobox protein Hox-A4;
DE   AltName: Full=Homeobox protein Hox-1.4;
DE   AltName: Full=Homeobox protein Hox-1D;
GN   Name=HOXA4; Synonyms=HOX1D;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA5_HUMAN              Reviewed;         270 AA.
AC   P20719; A4D179; O43367; Q96CY6;
DE   RecName: Full=Homeobox protein Hox-A5;
DE   AltName: Full=Homeobox protein Hox-1C;
GN   Name=HOXA5; Synonyms=HOX1C;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060435; P:bronchiole development; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0060764; P:cell-cell signaling involved in mammary gland development; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0060574; P:intestinal epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0060480; P:lung goblet cell differentiation; IEA:Ensembl.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060638; P:mesenchymal-epithelial cell signaling; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045639; P:positive regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0060535; P:trachea cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA6_HUMAN              Reviewed;         233 AA.
AC   P31267; A4D192; Q2M3G3; Q9UPM0;
DE   RecName: Full=Homeobox protein Hox-A6;
DE   AltName: Full=Homeobox protein Hox-1B;
GN   Name=HOXA6; Synonyms=HOX1B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA7_HUMAN              Reviewed;         230 AA.
AC   P31268; A4D191; O43368; O43486; O95655; Q9NSC8; Q9UDM1;
DE   RecName: Full=Homeobox protein Hox-A7;
DE   AltName: Full=Homeobox protein Hox 1.1;
DE   AltName: Full=Homeobox protein Hox-1A;
GN   Name=HOXA7; Synonyms=HOX1A;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; IDA:MGI.
DR   GO; GO:0002686; P:negative regulation of leukocyte migration; IDA:UniProtKB.
DR   GO; GO:0045656; P:negative regulation of monocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXA9_HUMAN              Reviewed;         272 AA.
AC   P31269; O43369; O43429; Q99820;
DE   RecName: Full=Homeobox protein Hox-A9;
DE   AltName: Full=Homeobox protein Hox-1G;
GN   Name=HOXA9; Synonyms=HOX1G;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0042118; P:endothelial cell activation; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB13_HUMAN             Reviewed;         284 AA.
AC   Q92826; B2R878; Q96QM4; Q99810;
DE   RecName: Full=Homeobox protein Hox-B13;
GN   Name=HOXB13;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0060743; P:epithelial cell maturation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR   GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB1_HUMAN              Reviewed;         301 AA.
AC   P14653;
DE   RecName: Full=Homeobox protein Hox-B1;
DE   AltName: Full=Homeobox protein Hox-2I;
GN   Name=HOXB1; Synonyms=HOX2I;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0021612; P:facial nerve structural organization; IEA:Ensembl.
DR   GO; GO:0021754; P:facial nucleus development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; TAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0021570; P:rhombomere 4 development; IEA:Ensembl.
DR   GO; GO:0021571; P:rhombomere 5 development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB2_HUMAN              Reviewed;         356 AA.
AC   P14652; P10913; P17485;
DE   RecName: Full=Homeobox protein Hox-B2;
DE   AltName: Full=Homeobox protein Hox-2.8;
DE   AltName: Full=Homeobox protein Hox-2H;
DE   AltName: Full=K8;
GN   Name=HOXB2; Synonyms=HOX2H;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0021612; P:facial nerve structural organization; IEA:Ensembl.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048857; P:neural nucleus development; IEA:Ensembl.
DR   GO; GO:0021569; P:rhombomere 3 development; IEA:Ensembl.
DR   GO; GO:0021570; P:rhombomere 4 development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB3_HUMAN              Reviewed;         431 AA.
AC   P14651; A8K567; D3DTV3; O95615; P17484;
DE   RecName: Full=Homeobox protein Hox-B3;
DE   AltName: Full=Homeobox protein Hox-2.7;
DE   AltName: Full=Homeobox protein Hox-2G;
GN   Name=HOXB3; Synonyms=HOX2G;
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0060324; P:face development; IEA:Ensembl.
DR   GO; GO:0021615; P:glossopharyngeal nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050767; P:regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0021546; P:rhombomere development; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB4_HUMAN              Reviewed;         251 AA.
AC   P17483; Q9NTA0;
DE   RecName: Full=Homeobox protein Hox-B4;
DE   AltName: Full=Homeobox protein Hox-2.6;
DE   AltName: Full=Homeobox protein Hox-2F;
GN   Name=HOXB4; Synonyms=HOX2F;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048539; P:bone marrow development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2000738; P:positive regulation of stem cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB5_HUMAN              Reviewed;         269 AA.
AC   P09067; B2RC69; P09069; Q17RP4;
DE   RecName: Full=Homeobox protein Hox-B5;
DE   AltName: Full=Homeobox protein HHO.C10;
DE   AltName: Full=Homeobox protein Hox-2A;
DE   AltName: Full=Homeobox protein Hu-1;
GN   Name=HOXB5; Synonyms=HOX2A;
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0045446; P:endothelial cell differentiation; IEA:Ensembl.
//
ID   HXB6_HUMAN              Reviewed;         224 AA.
AC   P17509; A8K835; D3DTV5; P09068; Q9HB11; Q9UGH2;
DE   RecName: Full=Homeobox protein Hox-B6;
DE   AltName: Full=Homeobox protein Hox-2.2;
DE   AltName: Full=Homeobox protein Hox-2B;
DE   AltName: Full=Homeobox protein Hu-2;
GN   Name=HOXB6; Synonyms=HOX2B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB7_HUMAN              Reviewed;         217 AA.
AC   P09629; A8K3N8; Q15957; Q53FN3; Q96BQ6;
DE   RecName: Full=Homeobox protein Hox-B7;
DE   AltName: Full=Homeobox protein HHO.C1;
DE   AltName: Full=Homeobox protein Hox-2C;
GN   Name=HOXB7; Synonyms=HOX2C;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB8_HUMAN              Reviewed;         243 AA.
AC   P17481; Q9H1I2;
DE   RecName: Full=Homeobox protein Hox-B8;
DE   AltName: Full=Homeobox protein Hox-2.4;
DE   AltName: Full=Homeobox protein Hox-2D;
GN   Name=HOXB8; Synonyms=HOX2D;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0021516; P:dorsal spinal cord development; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXB9_HUMAN              Reviewed;         250 AA.
AC   P17482; B2RDB7; Q9H1I1;
DE   RecName: Full=Homeobox protein Hox-B9;
DE   AltName: Full=Homeobox protein Hox-2.5;
DE   AltName: Full=Homeobox protein Hox-2E;
GN   Name=HOXB9; Synonyms=HOX2E;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC11_HUMAN             Reviewed;         304 AA.
AC   O43248; A8K7D1; Q96DH2;
DE   RecName: Full=Homeobox protein Hox-C11;
DE   AltName: Full=Homeobox protein Hox-3H;
GN   Name=HOXC11; Synonyms=HOX3H;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:NTNU_SB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:NTNU_SB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; TAS:ProtInc.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:NTNU_SB.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
//
ID   HXC12_HUMAN             Reviewed;         282 AA.
AC   P31275; Q9BXJ6;
DE   RecName: Full=Homeobox protein Hox-C12;
DE   AltName: Full=Homeobox protein Hox-3F;
GN   Name=HOXC12; Synonyms=HOC3F, HOX3F;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC13_HUMAN             Reviewed;         330 AA.
AC   P31276; Q5BL02; Q96J32; Q9NR24; Q9NYD5;
DE   RecName: Full=Homeobox protein Hox-C13;
DE   AltName: Full=Homeobox protein Hox-3G;
GN   Name=HOXC13; Synonyms=HOX3G;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0035878; P:nail development; IEA:Ensembl.
DR   GO; GO:0043587; P:tongue morphogenesis; IEA:Ensembl.
//
ID   HXC10_HUMAN             Reviewed;         342 AA.
AC   Q9NYD6; O15219; O15220; Q9BVD5;
DE   RecName: Full=Homeobox protein Hox-C10;
DE   AltName: Full=Homeobox protein Hox-3I;
GN   Name=HOXC10; Synonyms=HOX3I;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC4_HUMAN              Reviewed;         264 AA.
AC   P09017;
DE   RecName: Full=Homeobox protein Hox-C4;
DE   AltName: Full=Homeobox protein CP19;
DE   AltName: Full=Homeobox protein Hox-3E;
GN   Name=HOXC4; Synonyms=HOX3E;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC5_HUMAN              Reviewed;         222 AA.
AC   Q00444;
DE   RecName: Full=Homeobox protein Hox-C5;
DE   AltName: Full=Homeobox protein CP11;
DE   AltName: Full=Homeobox protein Hox-3D;
GN   Name=HOXC5; Synonyms=HOX3D;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC6_HUMAN              Reviewed;         235 AA.
AC   P09630; B2RBV2; Q6DK09;
DE   RecName: Full=Homeobox protein Hox-C6;
DE   AltName: Full=Homeobox protein CP25;
DE   AltName: Full=Homeobox protein HHO.C8;
DE   AltName: Full=Homeobox protein Hox-3C;
GN   Name=HOXC6; Synonyms=HOX3C;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC8_HUMAN              Reviewed;         242 AA.
AC   P31273; A8K4J4; O15221; O15362;
DE   RecName: Full=Homeobox protein Hox-C8;
DE   AltName: Full=Homeobox protein Hox-3A;
GN   Name=HOXC8; Synonyms=HOX3A;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXC9_HUMAN              Reviewed;         260 AA.
AC   P31274; B2RCN7; Q9H1I0;
DE   RecName: Full=Homeobox protein Hox-C9;
DE   AltName: Full=Homeobox protein Hox-3B;
GN   Name=HOXC9; Synonyms=HOX3B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD10_HUMAN             Reviewed;         340 AA.
AC   P28358; Q6NT10;
DE   RecName: Full=Homeobox protein Hox-D10;
DE   AltName: Full=Homeobox protein Hox-4D;
DE   AltName: Full=Homeobox protein Hox-4E;
GN   Name=HOXD10; Synonyms=HOX4D, HOX4E;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0035136; P:forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD11_HUMAN             Reviewed;         338 AA.
AC   P31277; A6NIS4; Q9NS02;
DE   RecName: Full=Homeobox protein Hox-D11;
DE   AltName: Full=Homeobox protein Hox-4F;
GN   Name=HOXD11; Synonyms=HOX4F;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0010720; P:positive regulation of cell development; IEA:Ensembl.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD12_HUMAN             Reviewed;         270 AA.
AC   P35452; B5MCP0; Q9NS03;
DE   RecName: Full=Homeobox protein Hox-D12;
DE   AltName: Full=Homeobox protein Hox-4H;
GN   Name=HOXD12; Synonyms=HOX4H;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD13_HUMAN             Reviewed;         343 AA.
AC   P35453;
DE   RecName: Full=Homeobox protein Hox-D13;
DE   AltName: Full=Homeobox protein Hox-4I;
GN   Name=HOXD13; Synonyms=HOX4I;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060602; P:branch elongation of an epithelium; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048619; P:embryonic hindgut morphogenesis; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0060571; P:morphogenesis of an epithelial fold; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   HXD1_HUMAN              Reviewed;         328 AA.
AC   Q9GZZ0; B2RAB4;
DE   RecName: Full=Homeobox protein Hox-D1;
DE   AltName: Full=Homeobox protein Hox-GG;
GN   Name=HOXD1; Synonyms=HOX4, HOX4G;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD3_HUMAN              Reviewed;         432 AA.
AC   P31249; Q99955; Q9BSC5;
DE   RecName: Full=Homeobox protein Hox-D3;
DE   AltName: Full=Homeobox protein Hox-4A;
GN   Name=HOXD3; Synonyms=HOX1D, HOX4A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; ISS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021615; P:glossopharyngeal nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IMP:UniProtKB.
//
ID   HXD4_HUMAN              Reviewed;         255 AA.
AC   P09016; B2R9R3; Q96AU0;
DE   RecName: Full=Homeobox protein Hox-D4;
DE   AltName: Full=Homeobox protein HHO.C13;
DE   AltName: Full=Homeobox protein Hox-4B;
DE   AltName: Full=Homeobox protein Hox-5.1;
GN   Name=HOXD4; Synonyms=HOX4B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD8_HUMAN              Reviewed;         290 AA.
AC   P13378; F8WBG7; Q5BL00; Q8IXZ1;
DE   RecName: Full=Homeobox protein Hox-D8;
DE   AltName: Full=Homeobox protein Hox-4E;
DE   AltName: Full=Homeobox protein Hox-5.4;
GN   Name=HOXD8; Synonyms=HOX4E;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXD9_HUMAN              Reviewed;         352 AA.
AC   P28356; Q86ST1;
DE   RecName: Full=Homeobox protein Hox-D9;
DE   AltName: Full=Homeobox protein Hox-4C;
DE   AltName: Full=Homeobox protein Hox-5.2;
GN   Name=HOXD9; Synonyms=HOX4C;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   HXK1_HUMAN              Reviewed;         917 AA.
AC   P19367; E9PCK0; O43443; O43444; O75574; Q5VTC3; Q96HC8; Q9NNZ4;
AC   Q9NNZ5;
DE   RecName: Full=Hexokinase-1;
DE            EC=2.7.1.1;
DE   AltName: Full=Brain form hexokinase;
DE   AltName: Full=Hexokinase type I;
DE            Short=HK I;
GN   Name=HK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IBA:RefGenome.
DR   GO; GO:0004340; F:glucokinase activity; IBA:RefGenome.
DR   GO; GO:0004396; F:hexokinase activity; TAS:ProtInc.
DR   GO; GO:0019158; F:mannokinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IBA:GOC.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IBA:RefGenome.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IBA:GOC.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IBA:RefGenome.
DR   GO; GO:0019318; P:hexose metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   HXK2_HUMAN              Reviewed;         917 AA.
AC   P52789; D6W5J2; Q8WU87; Q9UN82;
DE   RecName: Full=Hexokinase-2;
DE            EC=2.7.1.1;
DE   AltName: Full=Hexokinase type II;
DE            Short=HK II;
DE   AltName: Full=Muscle form hexokinase;
GN   Name=HK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IBA:RefGenome.
DR   GO; GO:0004340; F:glucokinase activity; IBA:RefGenome.
DR   GO; GO:0005536; F:glucose binding; IEA:Ensembl.
DR   GO; GO:0004396; F:hexokinase activity; TAS:ProtInc.
DR   GO; GO:0019158; F:mannokinase activity; IBA:RefGenome.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IBA:RefGenome.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IBA:GOC.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IBA:RefGenome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0046324; P:regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   HXK3_HUMAN              Reviewed;         923 AA.
AC   P52790; Q8N1E7;
DE   RecName: Full=Hexokinase-3;
DE            EC=2.7.1.1;
DE   AltName: Full=Hexokinase type III;
DE            Short=HK III;
GN   Name=HK3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008865; F:fructokinase activity; IBA:RefGenome.
DR   GO; GO:0004340; F:glucokinase activity; IBA:RefGenome.
DR   GO; GO:0004396; F:hexokinase activity; IDA:MGI.
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0019158; F:mannokinase activity; IBA:RefGenome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:GOC.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IBA:RefGenome.
DR   GO; GO:0051156; P:glucose 6-phosphate metabolic process; IBA:GOC.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0019318; P:hexose metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   HXK4_HUMAN              Reviewed;         465 AA.
AC   P35557; A4D2J2; A4D2J3; Q05810;
DE   RecName: Full=Glucokinase;
DE            EC=2.7.1.2;
DE   AltName: Full=Hexokinase type IV;
DE            Short=HK IV;
DE   AltName: Full=Hexokinase-4;
DE            Short=HK4;
DE   AltName: Full=Hexokinase-D;
GN   Name=GCK;
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004340; F:glucokinase activity; IDA:UniProtKB.
DR   GO; GO:0005536; F:glucose binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070509; P:calcium ion import; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IBA:RefGenome.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.
DR   GO; GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.
DR   GO; GO:0051594; P:detection of glucose; IMP:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0006739; P:NADP metabolic process; IEA:Ensembl.
DR   GO; GO:0032811; P:negative regulation of epinephrine secretion; IEA:Ensembl.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0006110; P:regulation of glycolytic process; NAS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0043266; P:regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0019932; P:second-messenger-mediated signaling; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   HYAL1_HUMAN             Reviewed;         435 AA.
AC   Q12794; Q6FH23; Q6PIZ6; Q7KYU2; Q7LE34; Q8NFK5; Q8NFK6; Q8NFK7;
AC   Q8NFK8; Q8NFK9; Q93013; Q9UKD5; Q9UNI8;
DE   RecName: Full=Hyaluronidase-1;
DE            Short=Hyal-1;
DE            EC=3.2.1.35;
DE   AltName: Full=Hyaluronoglucosaminidase-1;
DE   AltName: Full=Lung carcinoma protein 1;
DE            Short=LuCa-1;
DE   Flags: Precursor;
GN   Name=HYAL1; Synonyms=LUCA1;
DR   GO; GO:0050501; F:hyaluronan synthase activity; IDA:UniProtKB.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0051216; P:cartilage development; IEP:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071467; P:cellular response to pH; IDA:UniProtKB.
DR   GO; GO:0036120; P:cellular response to platelet-derived growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0071493; P:cellular response to UV-B; IDA:UniProtKB.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030213; P:hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030214; P:hyaluronan catabolic process; IDA:UniProtKB.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045927; P:positive regulation of growth; IDA:UniProtKB.
DR   GO; GO:1900106; P:positive regulation of hyaluranon cable assembly; IDA:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IDA:UniProtKB.
DR   GO; GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HYAL2_HUMAN             Reviewed;         473 AA.
AC   Q12891; B3KRZ2; O15177; Q9BW29;
DE   RecName: Full=Hyaluronidase-2;
DE            Short=Hyal-2;
DE            EC=3.2.1.35;
DE   AltName: Full=Hyaluronoglucosaminidase-2;
DE   AltName: Full=Lung carcinoma protein 2;
DE            Short=LuCa-2;
DE   Flags: Precursor;
GN   Name=HYAL2; Synonyms=LUCA2;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0005540; F:hyaluronic acid binding; IDA:UniProtKB.
DR   GO; GO:0033906; F:hyaluronoglucuronidase activity; IDA:UniProtKB.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030294; F:receptor signaling protein tyrosine kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0050431; F:transforming growth factor beta binding; ISS:BHF-UCL.
DR   GO; GO:0001618; F:virus receptor activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0051216; P:cartilage development; IEP:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0071493; P:cellular response to UV-B; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IDA:UniProtKB.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0030214; P:hyaluronan catabolic process; IDA:UniProtKB.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0042117; P:monocyte activation; IDA:UniProtKB.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0060586; P:multicellular organismal iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0010764; P:negative regulation of fibroblast migration; IDA:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:2000778; P:positive regulation of interleukin-6 secretion; IDA:UniProtKB.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IDA:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0035810; P:positive regulation of urine volume; ISS:UniProtKB.
DR   GO; GO:0070295; P:renal water absorption; ISS:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IEP:UniProtKB.
DR   GO; GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019087; P:transformation of host cell by virus; IDA:UniProtKB.
DR   GO; GO:0046718; P:viral entry into host cell; ISS:UniProtKB.
//
ID   HYAL4_HUMAN             Reviewed;         481 AA.
AC   Q2M3T9; D0VXG1; Q9UL99; Q9Y6T9;
DE   RecName: Full=Hyaluronidase-4;
DE            Short=Hyal-4;
DE            EC=3.2.1.35;
DE   AltName: Full=Chondroitin sulfate endo-beta-N-acetylgalactosaminidase;
DE   AltName: Full=Chondroitin sulfate hydrolase;
DE            Short=CSHY;
DE   AltName: Full=Hyaluronoglucosaminidase-4;
GN   Name=HYAL4;
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; IEA:Ensembl.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:ProtInc.
//
ID   HYAL3_HUMAN             Reviewed;         417 AA.
AC   O43820; O60540; Q8NFK2; Q8NFK3; Q8NFK4; Q96E56; Q9BRW9;
DE   RecName: Full=Hyaluronidase-3;
DE            Short=Hyal-3;
DE            EC=3.2.1.35;
DE   AltName: Full=Hyaluronoglucosaminidase-3;
DE   AltName: Full=Lung carcinoma protein 3;
DE            Short=LuCa-3;
DE   Flags: Precursor;
GN   Name=HYAL3; Synonyms=LUCA3;
DR   GO; GO:0033906; F:hyaluronoglucuronidase activity; IDA:UniProtKB.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0051216; P:cartilage development; IEP:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0071493; P:cellular response to UV-B; IDA:UniProtKB.
DR   GO; GO:0030214; P:hyaluronan catabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IEP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
//
ID   HYALP_HUMAN             Reviewed;         509 AA.
AC   P38567; Q8TC30;
DE   RecName: Full=Hyaluronidase PH-20;
DE            Short=Hyal-PH20;
DE            EC=3.2.1.35;
DE   AltName: Full=Hyaluronoglucosaminidase PH-20;
DE   AltName: Full=Sperm adhesion molecule 1;
DE   AltName: Full=Sperm surface protein PH-20;
DE   Flags: Precursor;
GN   Name=SPAM1; Synonyms=HYAL3, PH20;
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IEA:InterPro.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
//
ID   HYAS1_HUMAN             Reviewed;         578 AA.
AC   Q92839; Q14470; Q9NS49;
DE   RecName: Full=Hyaluronan synthase 1;
DE            EC=2.4.1.212;
DE   AltName: Full=Hyaluronate synthase 1;
DE   AltName: Full=Hyaluronic acid synthase 1;
DE            Short=HA synthase 1;
DE            Short=HuHAS1;
GN   Name=HAS1; Synonyms=HAS;
DR   GO; GO:0050501; F:hyaluronan synthase activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0036120; P:cellular response to platelet-derived growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0085029; P:extracellular matrix assembly; ISS:UniProtKB.
DR   GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:ProtInc.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030213; P:hyaluronan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0010764; P:negative regulation of fibroblast migration; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HYAS2_HUMAN             Reviewed;         552 AA.
AC   Q92819; Q32MM3;
DE   RecName: Full=Hyaluronan synthase 2;
DE            EC=2.4.1.212;
DE   AltName: Full=Hyaluronate synthase 2;
DE   AltName: Full=Hyaluronic acid synthase 2;
DE            Short=HA synthase 2;
GN   Name=HAS2;
DR   GO; GO:0050501; F:hyaluronan synthase activity; ISS:UniProtKB.
DR   GO; GO:0036302; P:atrioventricular canal development; ISS:UniProtKB.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0071498; P:cellular response to fluid shear stress; IEP:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.
DR   GO; GO:0036120; P:cellular response to platelet-derived growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:BHF-UCL.
DR   GO; GO:0090500; P:endocardial cushion to mesenchymal transition; ISS:UniProtKB.
DR   GO; GO:0085029; P:extracellular matrix assembly; ISS:UniProtKB.
DR   GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030213; P:hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:1900625; P:positive regulation of monocyte aggregation; IMP:BHF-UCL.
DR   GO; GO:0035810; P:positive regulation of urine volume; ISS:UniProtKB.
DR   GO; GO:0070295; P:renal water absorption; ISS:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
//
ID   HYAS3_HUMAN             Reviewed;         553 AA.
AC   O00219; A8K5T5; Q8WTZ0; Q9NYP0;
DE   RecName: Full=Hyaluronan synthase 3;
DE            EC=2.4.1.212;
DE   AltName: Full=Hyaluronate synthase 3;
DE   AltName: Full=Hyaluronic acid synthase 3;
DE            Short=HA synthase 3;
GN   Name=HAS3;
DR   GO; GO:0050501; F:hyaluronan synthase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0085029; P:extracellular matrix assembly; ISS:UniProtKB.
DR   GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030213; P:hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:1900106; P:positive regulation of hyaluranon cable assembly; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   HYCCI_HUMAN             Reviewed;         521 AA.
AC   Q9BYI3; A4D145; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6;
DE   RecName: Full=Hyccin;
DE   AltName: Full=Down-regulated by CTNNB1 protein A;
DE   AltName: Full=Protein FAM126A;
GN   Name=FAM126A; Synonyms=DRCTNNB1A;
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   HYDIN_HUMAN             Reviewed;        5121 AA.
AC   Q4G0P3; A6NC70; A6NLZ0; B4DQY4; B4DRN4; F5H6V3; Q8N3H8; Q8N3P6;
AC   Q8TC08; Q96JG3; Q96SS4; Q9H5U3; Q9H9B8; Q9NTI0; Q9UBE5;
DE   RecName: Full=Hydrocephalus-inducing protein homolog;
GN   Name=HYDIN; Synonyms=HYDIN1, KIAA1864;
//
ID   HYEP_HUMAN              Reviewed;         455 AA.
AC   P07099; B2R8N0; Q5VTJ6; Q9NP75; Q9NPE7; Q9NQU6; Q9NQU7; Q9NQU8;
AC   Q9NQU9; Q9NQV0; Q9NQV1; Q9NQV2;
DE   RecName: Full=Epoxide hydrolase 1;
DE            EC=3.3.2.9;
DE   AltName: Full=Epoxide hydratase;
DE   AltName: Full=Microsomal epoxide hydrolase;
GN   Name=EPHX1; Synonyms=EPHX, EPOX;
DR   GO; GO:0033961; F:cis-stilbene-oxide hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004301; F:epoxide hydrolase activity; TAS:ProtInc.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:UniProtKB-KW.
//
ID   HYES_HUMAN              Reviewed;         555 AA.
AC   P34913; B2Z3B1; B3KTU8; B3KUA0; G3V134; J3KPH7; Q16764; Q9HBJ1;
AC   Q9HBJ2;
DE   RecName: Full=Bifunctional epoxide hydrolase 2;
DE   Includes:
DE     RecName: Full=Cytosolic epoxide hydrolase 2;
DE              Short=CEH;
DE              EC=3.3.2.10;
DE     AltName: Full=Epoxide hydratase;
DE     AltName: Full=Soluble epoxide hydrolase;
DE              Short=SEH;
DE   Includes:
DE     RecName: Full=Lipid-phosphate phosphatase;
DE              EC=3.1.3.76;
GN   Name=EPHX2;
DR   GO; GO:0033885; F:10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004301; F:epoxide hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0042577; F:lipid phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0016791; F:phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0015643; F:toxic substance binding; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0017144; P:drug metabolic process; NAS:UniProtKB.
DR   GO; GO:0019373; P:epoxygenase P450 pathway; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0046839; P:phospholipid dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; NAS:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; NAS:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:UniProtKB.
DR   GO; GO:0090181; P:regulation of cholesterol metabolic process; IMP:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046272; P:stilbene catabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; NAS:UniProtKB.
//
ID   HYI_HUMAN               Reviewed;         277 AA.
AC   Q5T013; D3DPX4; D3DPX5; Q5Q9A2; Q7Z778; Q96S83; Q9BZR3; Q9BZR4;
DE   RecName: Full=Putative hydroxypyruvate isomerase;
DE            EC=5.3.1.22;
DE   AltName: Full=Endothelial cell apoptosis protein E-CE1;
GN   Name=HYI; ORFNames=HT036, SB156;
DR   GO; GO:0008903; F:hydroxypyruvate isomerase activity; IEA:UniProtKB-EC.
//
ID   HYKK_HUMAN              Reviewed;         373 AA.
AC   A2RU49; B7ZMA5; F8W6X5; Q6ZTN0;
DE   RecName: Full=Hydroxylysine kinase;
DE            Short=5-hydroxy-L-lysine kinase;
DE            EC=2.7.1.81;
DE   AltName: Full=Aminoglycoside phosphotransferase domain-containing protein 1;
GN   Name=HYKK; Synonyms=AGPHD1;
DR   GO; GO:0047992; F:hydroxylysine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
//
ID   HYLS1_HUMAN             Reviewed;         299 AA.
AC   Q96M11; B3KXI8; Q96BX9;
DE   RecName: Full=Hydrolethalus syndrome protein 1;
GN   Name=HYLS1; Synonyms=HLS;
//
ID   HYOU1_HUMAN             Reviewed;         999 AA.
AC   Q9Y4L1; A8C1Z0; Q2I204; Q53H25;
DE   RecName: Full=Hypoxia up-regulated protein 1;
DE   AltName: Full=150 kDa oxygen-regulated protein;
DE            Short=ORP-150;
DE   AltName: Full=170 kDa glucose-regulated protein;
DE            Short=GRP-170;
DE   Flags: Precursor;
GN   Name=HYOU1; Synonyms=GRP170, ORP150;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   HYPK_HUMAN              Reviewed;         129 AA.
AC   Q9NX55; C9JKJ0; O75408; Q8WUW8; Q9P024;
DE   RecName: Full=Huntingtin-interacting protein K;
DE   AltName: Full=Huntingtin yeast partner K;
GN   Name=HYPK; Synonyms=C15orf63; ORFNames=HSPC136;
//
ID   HYPM_HUMAN              Reviewed;         117 AA.
AC   O75409; A1A4D3;
DE   RecName: Full=Huntingtin-interacting protein M;
DE   AltName: Full=Huntingtin yeast partner M;
GN   Name=CXorf27; Synonyms=HYPM;
//
ID   I10R1_HUMAN             Reviewed;         578 AA.
AC   Q13651; A8K6I0; B0YJ27;
DE   RecName: Full=Interleukin-10 receptor subunit alpha;
DE            Short=IL-10 receptor subunit alpha;
DE            Short=IL-10R subunit alpha;
DE            Short=IL-10RA;
DE   AltName: Full=CDw210a;
DE   AltName: Full=Interleukin-10 receptor subunit 1;
DE            Short=IL-10R subunit 1;
DE            Short=IL-10R1;
DE   AltName: CD_antigen=CD210;
DE   Flags: Precursor;
GN   Name=IL10RA; Synonyms=IL10R;
DR   GO; GO:0004920; F:interleukin-10 receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   I10R2_HUMAN             Reviewed;         325 AA.
AC   Q08334; Q9BUU4;
DE   RecName: Full=Interleukin-10 receptor subunit beta;
DE            Short=IL-10 receptor subunit beta;
DE            Short=IL-10R subunit beta;
DE            Short=IL-10RB;
DE   AltName: Full=Cytokine receptor class-II member 4;
DE   AltName: Full=Cytokine receptor family 2 member 4;
DE            Short=CRF2-4;
DE   AltName: Full=Interleukin-10 receptor subunit 2;
DE            Short=IL-10R subunit 2;
DE            Short=IL-10R2;
DE   AltName: CD_antigen=CDw210b;
DE   Flags: Precursor;
GN   Name=IL10RB; Synonyms=CRFB4, D21S58, D21S66;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   I11RA_HUMAN             Reviewed;         422 AA.
AC   Q14626; Q16542; Q5VZ80; Q7KYJ7;
DE   RecName: Full=Interleukin-11 receptor subunit alpha;
DE            Short=IL-11 receptor subunit alpha;
DE            Short=IL-11R subunit alpha;
DE            Short=IL-11R-alpha;
DE            Short=IL-11RA;
DE   Flags: Precursor;
GN   Name=IL11RA;
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0032502; P:developmental process; IMP:UniProtKB.
DR   GO; GO:0060322; P:head development; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   I12R1_HUMAN             Reviewed;         662 AA.
AC   P42701; A8K308; B2RPF1; B7ZKK3; Q8N6Q7;
DE   RecName: Full=Interleukin-12 receptor subunit beta-1;
DE            Short=IL-12 receptor subunit beta-1;
DE            Short=IL-12R subunit beta-1;
DE            Short=IL-12R-beta-1;
DE            Short=IL-12RB1;
DE   AltName: Full=IL-12 receptor beta component;
DE   AltName: CD_antigen=CD212;
DE   Flags: Precursor;
GN   Name=IL12RB1; Synonyms=IL12R, IL12RB;
DR   GO; GO:0004896; F:cytokine receptor activity; TAS:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0035722; P:interleukin-12-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0038155; P:interleukin-23-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0043382; P:positive regulation of memory T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; ISS:BHF-UCL.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IDA:BHF-UCL.
DR   GO; GO:2000330; P:positive regulation of T-helper 17 cell lineage commitment; ISS:BHF-UCL.
DR   GO; GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IC:BHF-UCL.
//
ID   I12R2_HUMAN             Reviewed;         862 AA.
AC   Q99665; B1AN98; B7ZKL9; F5H7L6; Q2M3V3;
DE   RecName: Full=Interleukin-12 receptor subunit beta-2;
DE            Short=IL-12 receptor subunit beta-2;
DE            Short=IL-12R subunit beta-2;
DE            Short=IL-12R-beta-2;
DE            Short=IL-12RB2;
DE   Flags: Precursor;
GN   Name=IL12RB2;
DR   GO; GO:0004896; F:cytokine receptor activity; TAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   I13R1_HUMAN             Reviewed;         427 AA.
AC   P78552; O95646; Q5JSL4; Q99656;
DE   RecName: Full=Interleukin-13 receptor subunit alpha-1;
DE            Short=IL-13 receptor subunit alpha-1;
DE            Short=IL-13R subunit alpha-1;
DE            Short=IL-13R-alpha-1;
DE            Short=IL-13RA1;
DE   AltName: Full=Cancer/testis antigen 19;
DE            Short=CT19;
DE   AltName: CD_antigen=CD213a1;
DE   Flags: Precursor;
GN   Name=IL13RA1; Synonyms=IL13R, IL13RA;
DR   GO; GO:0016515; F:interleukin-13 receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IEA:Ensembl.
//
ID   I13R2_HUMAN             Reviewed;         380 AA.
AC   Q14627; A8K7E2; O00667;
DE   RecName: Full=Interleukin-13 receptor subunit alpha-2;
DE            Short=IL-13 receptor subunit alpha-2;
DE            Short=IL-13R subunit alpha-2;
DE            Short=IL-13R-alpha-2;
DE            Short=IL-13RA2;
DE   AltName: Full=Interleukin-13-binding protein;
DE   AltName: CD_antigen=CD213a2;
DE   Flags: Precursor;
GN   Name=IL13RA2; Synonyms=IL13R;
DR   GO; GO:0004896; F:cytokine receptor activity; TAS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   I15RA_HUMAN             Reviewed;         267 AA.
AC   Q13261; B4E2C2; Q5JVA1; Q5JVA2; Q5JVA4; Q6B0J2; Q7LDR4; Q7Z609;
DE   RecName: Full=Interleukin-15 receptor subunit alpha;
DE            Short=IL-15 receptor subunit alpha;
DE            Short=IL-15R-alpha;
DE            Short=IL-15RA;
DE   AltName: CD_antigen=CD215;
DE   Contains:
DE     RecName: Full=Soluble interleukin-15 receptor subunit alpha;
DE              Short=sIL-15 receptor subunit alpha;
DE              Short=sIL-15R-alpha;
DE              Short=sIL-15RA;
DE   Flags: Precursor;
GN   Name=IL15RA;
DR   GO; GO:0004896; F:cytokine receptor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0007259; P:JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   I17RA_HUMAN             Reviewed;         866 AA.
AC   Q96F46; O43844; Q20WK1;
DE   RecName: Full=Interleukin-17 receptor A;
DE            Short=IL-17 receptor A;
DE            Short=IL-17RA;
DE   AltName: Full=CDw217;
DE   AltName: CD_antigen=CD217;
DE   Flags: Precursor;
GN   Name=IL17RA; Synonyms=IL17R;
DR   GO; GO:0030368; F:interleukin-17 receptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:GOC.
DR   GO; GO:0072537; P:fibroblast activation; IDA:BHF-UCL.
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0032747; P:positive regulation of interleukin-23 production; IDA:BHF-UCL.
//
ID   I17EL_HUMAN             Reviewed;         336 AA.
AC   Q6ZVW7; A6NCN4; A6PVC1;
DE   RecName: Full=Putative interleukin-17 receptor E-like;
DE            Short=IL-17 receptor E-like;
DE            Short=IL-17RE-like;
GN   Name=IL17REL;
//
ID   I17RB_HUMAN             Reviewed;         502 AA.
AC   Q9NRM6; Q9BPZ0; Q9NRL4; Q9NRM5;
DE   RecName: Full=Interleukin-17 receptor B;
DE            Short=IL-17 receptor B;
DE            Short=IL-17RB;
DE   AltName: Full=Cytokine receptor-like 4;
DE   AltName: Full=IL-17 receptor homolog 1;
DE            Short=IL-17Rh1;
DE            Short=IL17Rh1;
DE   AltName: Full=Interleukin-17B receptor;
DE            Short=IL-17B receptor;
DE   Flags: Precursor;
GN   Name=IL17RB; Synonyms=CRL4, EVI27, IL17BR; ORFNames=UNQ2501/PRO19612;
DR   GO; GO:0004896; F:cytokine receptor activity; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:GOC.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   I17RC_HUMAN             Reviewed;         791 AA.
AC   Q8NAC3; E9PHG1; E9PHJ6; Q6UVY3; Q6UWD4; Q8NFS1; Q9BR97;
DE   RecName: Full=Interleukin-17 receptor C;
DE            Short=IL-17 receptor C;
DE            Short=IL-17RC;
DE   AltName: Full=Interleukin-17 receptor homolog;
DE            Short=IL17Rhom;
DE   AltName: Full=Interleukin-17 receptor-like protein;
DE            Short=IL-17RL;
DE   AltName: Full=ZcytoR14;
DE   Flags: Precursor;
GN   Name=IL17RC; ORFNames=UNQ6118/PRO20040/PRO38901;
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IDA:MGI.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
//
ID   I17RD_HUMAN             Reviewed;         739 AA.
AC   Q8NFM7; Q2NKP7; Q58EZ7; Q6RVF4; Q6UWI5; Q8N113; Q8NFS0; Q9UFA0;
DE   RecName: Full=Interleukin-17 receptor D;
DE            Short=IL-17 receptor D;
DE            Short=IL-17RD;
DE   AltName: Full=IL17Rhom;
DE   AltName: Full=Interleukin-17 receptor-like protein;
DE   AltName: Full=Sef homolog;
DE            Short=hSef;
DE   Flags: Precursor;
GN   Name=IL17RD; Synonyms=IL17RLM, SEF; ORFNames=UNQ6115/PRO20026;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   I18BP_HUMAN             Reviewed;         194 AA.
AC   O95998; B3KUZ0; B7WPK4; O95993; O96027; Q9NZA9; Q9UBR7;
DE   RecName: Full=Interleukin-18-binding protein;
DE            Short=IL-18BP;
DE   AltName: Full=Tadekinig-alfa;
DE   Flags: Precursor;
GN   Name=IL18BP;
DR   GO; GO:0042007; F:interleukin-18 binding; IDA:UniProtKB.
DR   GO; GO:0048019; F:receptor antagonist activity; TAS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:1900116; P:extracellular negative regulation of signal transduction; TAS:GOC.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042088; P:T-helper 1 type immune response; IDA:UniProtKB.
//
ID   I18RA_HUMAN             Reviewed;         599 AA.
AC   O95256; B2RPJ3; Q3KPE7; Q53TT4; Q53TU5;
DE   RecName: Full=Interleukin-18 receptor accessory protein;
DE            Short=IL-18 receptor accessory protein;
DE            Short=IL-18RAcP;
DE   AltName: Full=Accessory protein-like;
DE            Short=AcPL;
DE   AltName: Full=CD218 antigen-like family member B;
DE   AltName: Full=CDw218b;
DE   AltName: Full=IL-1R accessory protein-like;
DE            Short=IL-1RAcPL;
DE   AltName: Full=Interleukin-1 receptor 7;
DE            Short=IL-1R-7;
DE            Short=IL-1R7;
DE   AltName: Full=Interleukin-18 receptor accessory protein-like;
DE   AltName: Full=Interleukin-18 receptor beta;
DE            Short=IL-18R-beta;
DE            Short=IL-18Rbeta;
DE   AltName: CD_antigen=CD218b;
DE   Flags: Precursor;
GN   Name=IL18RAP; Synonyms=IL1R7;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
//
ID   I17RE_HUMAN             Reviewed;         667 AA.
AC   Q8NFR9; B2RB34; B2RNR1; B9EH65; Q6P532; Q8N8H7; Q8N8H8; Q8TEC2;
DE   RecName: Full=Interleukin-17 receptor E;
DE            Short=IL-17 receptor E;
DE            Short=IL-17RE;
DE   Flags: Precursor;
GN   Name=IL17RE; ORFNames=UNQ3056/PRO9877;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
//
ID   I20L2_HUMAN             Reviewed;         353 AA.
AC   Q9H9L3; D3DVC6; Q64KA2;
DE   RecName: Full=Interferon-stimulated 20 kDa exonuclease-like 2;
DE            EC=3.1.-.-;
GN   Name=ISG20L2; ORFNames=HSD-38, HSD38;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   I20RA_HUMAN             Reviewed;         553 AA.
AC   Q9UHF4; B4DLR5; F5H675; Q14CW2; Q6UWA9; Q96SH8;
DE   RecName: Full=Interleukin-20 receptor subunit alpha;
DE            Short=IL-20 receptor subunit alpha;
DE            Short=IL-20R-alpha;
DE            Short=IL-20RA;
DE   AltName: Full=Cytokine receptor class-II member 8;
DE   AltName: Full=Cytokine receptor family 2 member 8;
DE            Short=CRF2-8;
DE   AltName: Full=IL-20R1;
DE   AltName: Full=ZcytoR7;
DE   Flags: Precursor;
GN   Name=IL20RA; ORFNames=UNQ681/PRO1315;
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045124; P:regulation of bone resorption; IEA:Ensembl.
//
ID   I22R2_HUMAN             Reviewed;         263 AA.
AC   Q969J5; Q08AH7; Q6UWM1; Q96A41; Q96QR0;
DE   RecName: Full=Interleukin-22 receptor subunit alpha-2;
DE            Short=IL-22 receptor subunit alpha-2;
DE            Short=IL-22R-alpha-2;
DE            Short=IL-22RA2;
DE   AltName: Full=Cytokine receptor class-II member 10;
DE   AltName: Full=Cytokine receptor family 2 member 10;
DE            Short=CRF2-10;
DE   AltName: Full=Cytokine receptor family type 2, soluble 1;
DE            Short=CRF2-S1;
DE   AltName: Full=Interleukin-22-binding protein;
DE            Short=IL-22BP;
DE            Short=IL22BP;
DE   AltName: Full=ZcytoR16;
DE   Flags: Precursor;
GN   Name=IL22RA2; ORFNames=UNQ5793/PRO19598/PRO19822;
DR   GO; GO:0042017; F:interleukin-22 binding; IDA:UniProtKB.
DR   GO; GO:0042018; F:interleukin-22 receptor activity; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0042516; P:regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.
//
ID   I20RB_HUMAN             Reviewed;         311 AA.
AC   Q6UXL0; B4DL40; Q6P438; Q8IYY5; Q8TAJ7;
DE   RecName: Full=Interleukin-20 receptor subunit beta;
DE            Short=IL-20 receptor subunit beta;
DE            Short=IL-20R-beta;
DE            Short=IL-20RB;
DE   AltName: Full=Fibronectin type III domain containing 6;
DE            Short=FNDC6;
DE   AltName: Full=IL-20R2;
DE   Flags: Precursor;
GN   Name=IL20RB; Synonyms=DIRS1; ORFNames=UNQ557/PRO1114;
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0002765; P:immune response-inhibiting signal transduction; IEA:Ensembl.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0001808; P:negative regulation of type IV hypersensitivity; IEA:Ensembl.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
//
ID   I22R1_HUMAN             Reviewed;         574 AA.
AC   Q8N6P7; A8K839; B2R9Y9; Q9HB22;
DE   RecName: Full=Interleukin-22 receptor subunit alpha-1;
DE            Short=IL-22 receptor subunit alpha-1;
DE            Short=IL-22R-alpha-1;
DE            Short=IL-22RA1;
DE   AltName: Full=Cytokine receptor class-II member 9;
DE   AltName: Full=Cytokine receptor family 2 member 9;
DE            Short=CRF2-9;
DE   AltName: Full=ZcytoR11;
DE   Flags: Precursor;
GN   Name=IL22RA1; Synonyms=IL22R;
DR   GO; GO:0004904; F:interferon receptor activity; TAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
//
ID   I23O1_HUMAN             Reviewed;         403 AA.
AC   P14902; Q540B4;
DE   RecName: Full=Indoleamine 2,3-dioxygenase 1;
DE            Short=IDO-1;
DE            EC=1.13.11.52;
DE   AltName: Full=Indoleamine-pyrrole 2,3-dioxygenase;
GN   Name=IDO1; Synonyms=IDO, INDO;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0002534; P:cytokine production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0034276; P:kynurenic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl.
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0070233; P:negative regulation of T cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0002678; P:positive regulation of chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0002666; P:positive regulation of T cell tolerance induction; IEA:Ensembl.
DR   GO; GO:0002830; P:positive regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0036269; P:swimming behavior; IEA:Ensembl.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:UniProtKB-UniPathway.
//
ID   I23O2_HUMAN             Reviewed;         407 AA.
AC   Q6ZQW0; A4UD41;
DE   RecName: Full=Indoleamine 2,3-dioxygenase 2;
DE            Short=IDO-2;
DE            EC=1.13.11.-;
DE   AltName: Full=Indoleamine 2,3-dioxygenase-like protein 1;
DE   AltName: Full=Indoleamine-pyrrole 2,3-dioxygenase-like protein 1;
GN   Name=IDO2; Synonyms=INDOL1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB.
//
ID   I27L2_HUMAN             Reviewed;         130 AA.
AC   Q9H2X8; Q8TBD7; Q9NYL0;
DE   RecName: Full=Interferon alpha-inducible protein 27-like protein 2;
DE   AltName: Full=Interferon-stimulated gene 12b protein;
DE            Short=ISG12(b);
DE   AltName: Full=Protein TLH29;
DE   AltName: Full=pIFI27-like protein;
DE   Flags: Precursor;
GN   Name=IFI27L2; Synonyms=FAM14A, TLH29;
//
ID   I27L1_HUMAN             Reviewed;         104 AA.
AC   Q96BM0;
DE   RecName: Full=Interferon alpha-inducible protein 27-like protein 1;
DE   AltName: Full=Interferon-stimulated gene 12c protein;
DE            Short=ISG12(c);
GN   Name=IFI27L1; Synonyms=FAM14B;
//
ID   I27RA_HUMAN             Reviewed;         636 AA.
AC   Q6UWB1; A0N0L1; O60624;
DE   RecName: Full=Interleukin-27 receptor subunit alpha;
DE            Short=IL-27 receptor subunit alpha;
DE            Short=IL-27R subunit alpha;
DE            Short=IL-27R-alpha;
DE            Short=IL-27RA;
DE   AltName: Full=Cytokine receptor WSX-1;
DE   AltName: Full=Cytokine receptor-like 1;
DE   AltName: Full=Type I T-cell cytokine receptor;
DE            Short=TCCR;
DE   AltName: Full=ZcytoR1;
DE   Flags: Precursor;
GN   Name=IL27RA; Synonyms=CRL1, TCCR, WSX1; ORFNames=UNQ296/PRO336;
DR   GO; GO:0045509; F:interleukin-27 receptor activity; IEA:Ensembl.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002829; P:negative regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IEA:Ensembl.
DR   GO; GO:0048302; P:regulation of isotype switching to IgG isotypes; IEA:Ensembl.
//
ID   I2BP2_HUMAN             Reviewed;         587 AA.
AC   Q7Z5L9; B1AM35; B1AM36; Q6P083; Q7Z5L8; Q8N351; Q8WUH8;
DE   RecName: Full=Interferon regulatory factor 2-binding protein 2;
DE            Short=IRF-2-binding protein 2;
DE            Short=IRF-2BP2;
GN   Name=IRF2BP2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   I2BP1_HUMAN             Reviewed;         584 AA.
AC   Q8IU81; Q53EL7; Q6DC95; Q9BRZ9; Q9Y4P4;
DE   RecName: Full=Interferon regulatory factor 2-binding protein 1;
DE            Short=IRF-2-binding protein 1;
DE            Short=IRF-2BP1;
DE   AltName: Full=Probable E3 ubiquitin-protein ligase IRF2BP1;
DE            EC=6.3.2.-;
GN   Name=IRF2BP1;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   I2BPL_HUMAN             Reviewed;         796 AA.
AC   Q9H1B7; Q8NDQ2; Q96JG2; Q9H3I7;
DE   RecName: Full=Interferon regulatory factor 2-binding protein-like;
DE   AltName: Full=Enhanced at puberty protein 1;
GN   Name=IRF2BPL; Synonyms=C14orf4, EAP1, KIAA1865; ORFNames=My039;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   I36RA_HUMAN             Reviewed;         155 AA.
AC   Q9UBH0; A8K2I4; Q56AT9; Q7RTZ6;
DE   RecName: Full=Interleukin-36 receptor antagonist protein;
DE   AltName: Full=FIL1 delta;
DE   AltName: Full=IL-1-related protein 3;
DE            Short=IL-1RP3;
DE   AltName: Full=Interleukin-1 HY1;
DE            Short=IL-1HY1;
DE   AltName: Full=Interleukin-1 delta;
DE            Short=IL-1 delta;
DE   AltName: Full=Interleukin-1 family member 5;
DE            Short=IL-1F5;
DE   AltName: Full=Interleukin-1 receptor antagonist homolog 1;
DE            Short=IL-1ra homolog 1;
DE   AltName: Full=Interleukin-1-like protein 1;
DE            Short=IL-1L1;
GN   Name=IL36RN; Synonyms=FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3;
GN   ORFNames=UNQ1896/PRO4342;
DR   GO; GO:0005152; F:interleukin-1 receptor antagonist activity; TAS:ProtInc.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
//
ID   I4E1B_HUMAN             Reviewed;         242 AA.
AC   A6NMX2;
DE   RecName: Full=Eukaryotic translation initiation factor 4E type 1B;
GN   Name=EIF4E1B;
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   I5P1_HUMAN              Reviewed;         412 AA.
AC   Q14642; D3DXI3; Q14640; Q5JSF1;
DE   RecName: Full=Type I inositol 1,4,5-trisphosphate 5-phosphatase;
DE            Short=5PTase;
DE            EC=3.1.3.56;
DE   Flags: Precursor;
GN   Name=INPP5A;
DR   GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0042731; F:PH domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   I5P2_HUMAN              Reviewed;         993 AA.
AC   P32019; C9J6U5; Q5VSG9; Q5VSH0; Q5VSH1; Q658Q5; Q6P6D4; Q6PD53;
AC   Q86YE1;
DE   RecName: Full=Type II inositol 1,4,5-trisphosphate 5-phosphatase;
DE            EC=3.1.3.36;
DE   AltName: Full=75 kDa inositol polyphosphate-5-phosphatase;
DE   AltName: Full=Phosphoinositide 5-phosphatase;
DE            Short=5PTase;
DE   Flags: Precursor;
GN   Name=INPP5B; Synonyms=OCRL2;
DR   GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0070613; P:regulation of protein processing; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   IAH1_HUMAN              Reviewed;         248 AA.
AC   Q2TAA2;
DE   RecName: Full=Isoamyl acetate-hydrolyzing esterase 1 homolog;
DE            EC=3.1.-.-;
GN   Name=IAH1;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   IAPP_HUMAN              Reviewed;          89 AA.
AC   P10997; Q0ZD87; Q14598;
DE   RecName: Full=Islet amyloid polypeptide;
DE   AltName: Full=Amylin;
DE   AltName: Full=Diabetes-associated peptide;
DE            Short=DAP;
DE   AltName: Full=Insulinoma amyloid peptide;
DE   Flags: Precursor;
GN   Name=IAPP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IASPP_HUMAN             Reviewed;         828 AA.
AC   Q8WUF5; Q2PNZ9; Q5DU71; Q5I1X4; Q6P1R7; Q6PKF8; Q9Y290;
DE   RecName: Full=RelA-associated inhibitor;
DE   AltName: Full=Inhibitor of ASPP protein;
DE            Short=Protein iASPP;
DE   AltName: Full=NFkB-interacting protein 1;
DE   AltName: Full=PPP1R13B-like protein;
GN   Name=PPP1R13L; Synonyms=IASPP, NKIP1, PPP1R13BL, RAI;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; IEA:Ensembl.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0042633; P:hair cycle; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048871; P:multicellular organismal homeostasis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0003229; P:ventricular cardiac muscle tissue development; IEA:Ensembl.
//
ID   IBAS1_HUMAN             Reviewed;         110 AA.
AC   B1ANH7;
DE   RecName: Full=Putative uncharacterized protein IBA57-AS1;
DE   AltName: Full=IBA57 antisense RNA 1;
DE   AltName: Full=IBA57 antisense gene protein 1;
GN   Name=IBA57-AS1; Synonyms=C1orf148;
//
ID   IBP1_HUMAN              Reviewed;         259 AA.
AC   P08833; A4D2F4; D3DVL9; Q8IYP5;
DE   RecName: Full=Insulin-like growth factor-binding protein 1;
DE            Short=IBP-1;
DE            Short=IGF-binding protein 1;
DE            Short=IGFBP-1;
DE   AltName: Full=Placental protein 12;
DE            Short=PP12;
DE   Flags: Precursor;
GN   Name=IGFBP1; Synonyms=IBP1;
DR   GO; GO:0005520; F:insulin-like growth factor binding; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
//
ID   IBP2_HUMAN              Reviewed;         325 AA.
AC   P18065; Q14619; Q9UCL3;
DE   RecName: Full=Insulin-like growth factor-binding protein 2;
DE            Short=IBP-2;
DE            Short=IGF-binding protein 2;
DE            Short=IGFBP-2;
DE   Flags: Precursor;
GN   Name=IGFBP2; Synonyms=BP2, IBP2;
DR   GO; GO:0031994; F:insulin-like growth factor I binding; IDA:UniProtKB.
DR   GO; GO:0031995; F:insulin-like growth factor II binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0043567; P:regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
//
ID   IBP3_HUMAN              Reviewed;         291 AA.
AC   P17936; A4D2F5; D3DVM0; Q2V509; Q6P1M6; Q9UCL4;
DE   RecName: Full=Insulin-like growth factor-binding protein 3;
DE            Short=IBP-3;
DE            Short=IGF-binding protein 3;
DE            Short=IGFBP-3;
DE   Flags: Precursor;
GN   Name=IGFBP3; Synonyms=IBP3;
DR   GO; GO:0005520; F:insulin-like growth factor binding; NAS:UniProtKB.
DR   GO; GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008160; F:protein tyrosine phosphatase activator activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0009968; P:negative regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:MGI.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0044342; P:type B pancreatic cell proliferation; IEA:Ensembl.
//
ID   IBP4_HUMAN              Reviewed;         258 AA.
AC   P22692; A0N9W2; Q5U012; Q9UCL6;
DE   RecName: Full=Insulin-like growth factor-binding protein 4;
DE            Short=IBP-4;
DE            Short=IGF-binding protein 4;
DE            Short=IGFBP-4;
DE   Flags: Precursor;
GN   Name=IGFBP4; Synonyms=IBP4;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044342; P:type B pancreatic cell proliferation; IEA:Ensembl.
//
ID   IBP5_HUMAN              Reviewed;         272 AA.
AC   P24593; Q5U0A3;
DE   RecName: Full=Insulin-like growth factor-binding protein 5;
DE            Short=IBP-5;
DE            Short=IGF-binding protein 5;
DE            Short=IGFBP-5;
DE   Flags: Precursor;
GN   Name=IGFBP5; Synonyms=IBP5;
DR   GO; GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0060056; P:mammary gland involution; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0048630; P:skeletal muscle tissue growth; IEA:Ensembl.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0044342; P:type B pancreatic cell proliferation; IEA:Ensembl.
//
ID   IBP6_HUMAN              Reviewed;         240 AA.
AC   P24592; Q14492;
DE   RecName: Full=Insulin-like growth factor-binding protein 6;
DE            Short=IBP-6;
DE            Short=IGF-binding protein 6;
DE            Short=IGFBP-6;
DE   Flags: Precursor;
GN   Name=IGFBP6; Synonyms=IBP6;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   IBP7_HUMAN              Reviewed;         282 AA.
AC   Q16270; B4E1N2; B7Z9W7; Q07822; Q53YE6; Q9UCA8;
DE   RecName: Full=Insulin-like growth factor-binding protein 7;
DE            Short=IBP-7;
DE            Short=IGF-binding protein 7;
DE            Short=IGFBP-7;
DE   AltName: Full=IGFBP-rP1;
DE   AltName: Full=MAC25 protein;
DE   AltName: Full=PGI2-stimulating factor;
DE   AltName: Full=Prostacyclin-stimulating factor;
DE   AltName: Full=Tumor-derived adhesion factor;
DE            Short=TAF;
DE   Flags: Precursor;
GN   Name=IGFBP7; Synonyms=MAC25, PSF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051414; P:response to cortisol; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   IBPL1_HUMAN             Reviewed;         278 AA.
AC   Q8WX77;
DE   RecName: Full=Insulin-like growth factor-binding protein-like 1;
DE   AltName: Full=IGFBP-related protein 10;
DE   AltName: Full=Insulin-like growth factor-binding-related protein 4;
DE            Short=IGFBP-rP4;
DE   Flags: Precursor;
GN   Name=IGFBPL1; Synonyms=IGFBPRP4;
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
//
ID   IBTK_HUMAN              Reviewed;        1353 AA.
AC   Q9P2D0; Q2QKU2; Q2QKU3; Q2QKU4; Q5TFD7; Q5TFD9; Q8IUQ9; Q8IUY7;
AC   Q8TAI4; Q9HBI8; Q9Y3T8;
DE   RecName: Full=Inhibitor of Bruton tyrosine kinase;
DE            Short=IBtk;
GN   Name=IBTK; Synonyms=BTKI, KIAA1417;
DR   GO; GO:0019901; F:protein kinase binding; IDA:MGI.
DR   GO; GO:0030292; F:protein tyrosine kinase inhibitor activity; IDA:MGI.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:MGI.
//
ID   IC1_HUMAN               Reviewed;         500 AA.
AC   P05155; A6NMU0; A8KAI9; B2R6L5; Q16304; Q547W3; Q59EI5; Q7Z455;
AC   Q96FE0; Q9UC49; Q9UCF9;
DE   RecName: Full=Plasma protease C1 inhibitor;
DE            Short=C1 Inh;
DE            Short=C1Inh;
DE   AltName: Full=C1 esterase inhibitor;
DE   AltName: Full=C1-inhibiting factor;
DE   AltName: Full=Serpin G1;
DE   Flags: Precursor;
GN   Name=SERPING1; Synonyms=C1IN, C1NH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0001869; P:negative regulation of complement activation, lectin pathway; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   ICA1L_HUMAN             Reviewed;         482 AA.
AC   Q8NDH6; B3KRW6; Q53P45; Q53QZ4; Q53T97; Q96N47; Q96Q32; Q9BVQ2;
DE   RecName: Full=Islet cell autoantigen 1-like protein;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein;
GN   Name=ICA1L; Synonyms=ALS2CR14, ALS2CR15;
//
ID   ICA69_HUMAN             Reviewed;         483 AA.
AC   Q05084; A8K7U1; B3FTQ2; P78506; Q13824;
DE   RecName: Full=Islet cell autoantigen 1;
DE   AltName: Full=69 kDa islet cell autoantigen;
DE            Short=ICA69;
DE   AltName: Full=Islet cell autoantigen p69;
DE            Short=ICAp69;
DE            Short=p69;
GN   Name=ICA1;
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
//
ID   ICAL_HUMAN              Reviewed;         708 AA.
AC   P20810; G5E946; G5E9D3; O95360; Q05DE8; Q7Z4K0; Q96D08; Q9H1Z5;
DE   RecName: Full=Calpastatin;
DE   AltName: Full=Calpain inhibitor;
DE   AltName: Full=Sperm BS-17 component;
GN   Name=CAST;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:2000675; P:negative regulation of type B pancreatic cell apoptotic process; IDA:BHF-UCL.
//
ID   ICAM1_HUMAN             Reviewed;         532 AA.
AC   P05362; B2R6M3; Q5NKV7; Q96B50;
DE   RecName: Full=Intercellular adhesion molecule 1;
DE            Short=ICAM-1;
DE   AltName: Full=Major group rhinovirus receptor;
DE   AltName: CD_antigen=CD54;
DE   Flags: Precursor;
GN   Name=ICAM1;
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0051856; ?:?; IDA:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0071312; P:cellular response to alkaloid; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0031669; P:cellular response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IGI:UniProt.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; IEP:BHF-UCL.
DR   GO; GO:0022614; P:membrane to membrane docking; IEP:BHF-UCL.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0002693; P:positive regulation of cellular extravasation; IMP:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0046813; P:receptor-mediated virion attachment to host cell; IDA:BHF-UCL.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0001910; P:regulation of leukocyte mediated cytotoxicity; TAS:BHF-UCL.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0034698; P:response to gonadotropin; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0010477; P:response to sulfur dioxide; IEA:Ensembl.
DR   GO; GO:0002291; P:T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IMP:BHF-UCL.
DR   GO; GO:0002457; P:T cell antigen processing and presentation; IEA:Ensembl.
//
ID   ICAM2_HUMAN             Reviewed;         275 AA.
AC   P13598; Q14600;
DE   RecName: Full=Intercellular adhesion molecule 2;
DE            Short=ICAM-2;
DE   AltName: CD_antigen=CD102;
DE   Flags: Precursor;
GN   Name=ICAM2;
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   ICAM3_HUMAN             Reviewed;         547 AA.
AC   P32942; Q6PD68;
DE   RecName: Full=Intercellular adhesion molecule 3;
DE            Short=ICAM-3;
DE   AltName: Full=CDw50;
DE   AltName: Full=ICAM-R;
DE   AltName: CD_antigen=CD50;
DE   Flags: Precursor;
GN   Name=ICAM3;
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   ICAM5_HUMAN             Reviewed;         924 AA.
AC   Q9UMF0; Q9Y6F3;
DE   RecName: Full=Intercellular adhesion molecule 5;
DE            Short=ICAM-5;
DE   AltName: Full=Telencephalin;
DE   Flags: Precursor;
GN   Name=ICAM5; Synonyms=TLCN, TLN;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0006909; P:phagocytosis; IEA:Ensembl.
//
ID   ICAM4_HUMAN             Reviewed;         271 AA.
AC   Q14773; A0M8X2; Q14771; Q14772; Q16375; Q9BWR0;
DE   RecName: Full=Intercellular adhesion molecule 4;
DE            Short=ICAM-4;
DE   AltName: Full=Landsteiner-Wiener blood group glycoprotein;
DE            Short=LW blood group protein;
DE   AltName: CD_antigen=CD242;
DE   Flags: Precursor;
GN   Name=ICAM4; Synonyms=LW;
DR   GO; GO:0005178; F:integrin binding; TAS:ProtInc.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   ICEF1_HUMAN             Reviewed;         437 AA.
AC   Q8WWN9; A8K1K2; B7ZL78; B7ZL80; O43153; Q5HYL8;
DE   RecName: Full=Interactor protein for cytohesin exchange factors 1;
DE   AltName: Full=Phosphoinositide-binding protein PIP3-E;
GN   Name=IPCEF1; Synonyms=KIAA0403;
DR   GO; GO:0005344; F:oxygen transporter activity; NAS:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:GOC.
DR   GO; GO:0015671; P:oxygen transport; NAS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
//
ID   ICK_HUMAN               Reviewed;         632 AA.
AC   Q9UPZ9; A7MD41; O75985; Q5THL2; Q8IYH8; Q9BX17; Q9NYX3;
DE   RecName: Full=Serine/threonine-protein kinase ICK;
DE            EC=2.7.11.22;
DE   AltName: Full=Intestinal cell kinase;
DE            Short=hICK;
DE   AltName: Full=Laryngeal cancer kinase 2;
DE            Short=LCK2;
DE   AltName: Full=MAK-related kinase;
DE            Short=MRK;
GN   Name=ICK; Synonyms=KIAA0936;
DR   GuidetoPHARMACOLOGY; 2038; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   ICLN_HUMAN              Reviewed;         237 AA.
AC   P54105; B2RCS9; Q0VDK6; Q9NRD2; Q9NRD3;
DE   RecName: Full=Methylosome subunit pICln;
DE   AltName: Full=Chloride channel, nucleotide sensitive 1A;
DE   AltName: Full=Chloride conductance regulatory protein ICln;
DE            Short=I(Cln);
DE   AltName: Full=Chloride ion current inducer protein;
DE            Short=ClCI;
DE   AltName: Full=Reticulocyte pICln;
GN   Name=CLNS1A; Synonyms=CLCI, ICLN;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   ICMT_HUMAN              Reviewed;         284 AA.
AC   O60725; Q6FHT0;
DE   RecName: Full=Protein-S-isoprenylcysteine O-methyltransferase;
DE            EC=2.1.1.100;
DE   AltName: Full=Isoprenylcysteine carboxylmethyltransferase;
DE   AltName: Full=Prenylated protein carboxyl methyltransferase;
DE            Short=PPMT;
DE   AltName: Full=Prenylcysteine carboxyl methyltransferase;
DE            Short=pcCMT;
GN   Name=ICMT; Synonyms=PCCMT;
DR   GO; GO:0008140; F:cAMP response element binding protein binding; IEA:Ensembl.
DR   GO; GO:0003880; F:protein C-terminal carboxyl O-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0004671; F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006481; P:C-terminal protein methylation; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006612; P:protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0046578; P:regulation of Ras protein signal transduction; IEA:Ensembl.
//
ID   ICOS_HUMAN              Reviewed;         199 AA.
AC   Q9Y6W8; Q8N6W8;
DE   RecName: Full=Inducible T-cell costimulator;
DE   AltName: Full=Activation-inducible lymphocyte immunomediatory molecule;
DE   AltName: CD_antigen=CD278;
DE   Flags: Precursor;
GN   Name=ICOS; Synonyms=AILIM;
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0002517; P:T cell tolerance induction; IEA:Ensembl.
//
ID   ICOSL_HUMAN             Reviewed;         302 AA.
AC   O75144; A8MUZ1; Q9HD18; Q9NRQ1;
DE   RecName: Full=ICOS ligand;
DE   AltName: Full=B7 homolog 2;
DE            Short=B7-H2;
DE   AltName: Full=B7-like protein Gl50;
DE   AltName: Full=B7-related protein 1;
DE            Short=B7RP-1;
DE   AltName: CD_antigen=CD275;
DE   Flags: Precursor;
GN   Name=ICOSLG; Synonyms=B7H2, B7RP1, ICOSL, KIAA0653;
DR   GO; GO:0005102; F:receptor binding; TAS:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; NAS:UniProtKB.
DR   GO; GO:0006972; P:hyperosmotic response; NAS:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; TAS:UniProtKB.
DR   GO; GO:0045404; P:positive regulation of interleukin-4 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   ICT1_HUMAN              Reviewed;         206 AA.
AC   Q14197; B2RAD1; Q53HM7; Q53Y11;
DE   RecName: Full=Peptidyl-tRNA hydrolase ICT1, mitochondrial;
DE            EC=3.1.1.29;
DE   AltName: Full=39S ribosomal protein L58, mitochondrial;
DE            Short=MRP-L58;
DE   AltName: Full=Digestion substraction 1;
DE            Short=DS-1;
DE   AltName: Full=Immature colon carcinoma transcript 1 protein;
DE   Flags: Precursor;
GN   Name=ICT1; Synonyms=DS1;
DR   GO; GO:0004045; F:aminoacyl-tRNA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0016150; F:translation release factor activity, codon nonspecific; IDA:UniProtKB.
DR   GO; GO:0070126; P:mitochondrial translational termination; IDA:UniProtKB.
//
ID   ID1_HUMAN               Reviewed;         155 AA.
AC   P41134; A8K537; E1P5L4; O00651; O00652; Q16371; Q16377; Q5TE66;
AC   Q5TE67; Q969Z7; Q9H0Z5; Q9H109;
DE   RecName: Full=DNA-binding protein inhibitor ID-1;
DE   AltName: Full=Class B basic helix-loop-helix protein 24;
DE            Short=bHLHb24;
DE   AltName: Full=Inhibitor of DNA binding 1;
GN   Name=ID1; Synonyms=BHLHB24, ID;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; TAS:BHF-UCL.
DR   GO; GO:0048514; P:blood vessel morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0032963; P:collagen metabolic process; IEA:Ensembl.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0060425; P:lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0060426; P:lung vasculature development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:GDB.
DR   GO; GO:0010621; P:negative regulation of transcription by transcription factor localization; TAS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:GDB.
DR   GO; GO:0031648; P:protein destabilization; IEA:Ensembl.
DR   GO; GO:0045765; P:regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:BHF-UCL.
//
ID   ID2B_HUMAN              Reviewed;          36 AA.
AC   Q14602;
DE   RecName: Full=Putative DNA-binding protein inhibitor ID-2B;
DE   AltName: Full=Inhibitor of DNA binding 2B;
GN   Name=ID2B;
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ID2_HUMAN               Reviewed;         134 AA.
AC   Q02363;
DE   RecName: Full=DNA-binding protein inhibitor ID-2;
DE   AltName: Full=Class B basic helix-loop-helix protein 26;
DE            Short=bHLHb26;
DE   AltName: Full=Inhibitor of DNA binding 2;
GN   Name=ID2; Synonyms=BHLHB26;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0003166; P:bundle of His development; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0090398; P:cellular senescence; ISS:UniProtKB.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061031; P:endodermal digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009649; P:entrainment of circadian clock; IEA:Ensembl.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0061030; P:epithelial cell differentiation involved in mammary gland alveolus development; ISS:UniProtKB.
DR   GO; GO:0060749; P:mammary gland alveolus development; ISS:UniProtKB.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0003149; P:membranous septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0045578; P:negative regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:2000178; P:negative regulation of neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:GDB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:GDB.
DR   GO; GO:0048663; P:neuron fate commitment; ISS:UniProtKB.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0071931; P:positive regulation of transcription involved in G1/S transition of mitotic cell cycle; IC:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
//
ID   ID3_HUMAN               Reviewed;         119 AA.
AC   Q02535; A8K1T8; O75641;
DE   RecName: Full=DNA-binding protein inhibitor ID-3;
DE   AltName: Full=Class B basic helix-loop-helix protein 25;
DE            Short=bHLHb25;
DE   AltName: Full=Helix-loop-helix protein HEIR-1;
DE   AltName: Full=ID-like protein inhibitor HLH 1R21;
DE   AltName: Full=Inhibitor of DNA binding 3;
GN   Name=ID3; Synonyms=1R21, BHLHB25, HEIR1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:GDB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:GDB.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:Ensembl.
//
ID   ID4_HUMAN               Reviewed;         161 AA.
AC   P47928; Q13005;
DE   RecName: Full=DNA-binding protein inhibitor ID-4;
DE   AltName: Full=Class B basic helix-loop-helix protein 27;
DE            Short=bHLHb27;
DE   AltName: Full=Inhibitor of DNA binding 4;
GN   Name=ID4; Synonyms=BHLHB27;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:GDB.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   IDAS1_HUMAN             Reviewed;         188 AA.
AC   Q9NZ38;
DE   RecName: Full=Uncharacterized protein IDI2-AS1;
DE   AltName: Full=IDI2 antisense RNA 1;
DE   AltName: Full=IDI2 antisense gene protein 1;
GN   Name=IDI2-AS1; Synonyms=C10orf110; ORFNames=HT009;
//
ID   IDD_HUMAN               Reviewed;         550 AA.
AC   P98153; A6NIB5; A8K6K5; B7Z935;
DE   RecName: Full=Integral membrane protein DGCR2/IDD;
DE   Flags: Precursor;
GN   Name=DGCR2; Synonyms=IDD, KIAA0163;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
//
ID   IDE_HUMAN               Reviewed;        1019 AA.
AC   P14735; B2R721; B7ZAU2; D3DR35; Q5T5N2;
DE   RecName: Full=Insulin-degrading enzyme;
DE            EC=3.4.24.56;
DE   AltName: Full=Abeta-degrading protease;
DE   AltName: Full=Insulin protease;
DE            Short=Insulinase;
DE   AltName: Full=Insulysin;
GN   Name=IDE;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IEA:Ensembl.
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0031626; F:beta-endorphin binding; IEA:Ensembl.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProtKB.
DR   GO; GO:0043559; F:insulin binding; IDA:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.
DR   GO; GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.
DR   GO; GO:0008340; P:determination of adult lifespan; IDA:UniProtKB.
DR   GO; GO:0042447; P:hormone catabolic process; IEA:Ensembl.
DR   GO; GO:1901143; P:insulin catabolic process; IDA:UniProtKB.
DR   GO; GO:1901142; P:insulin metabolic process; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0010992; P:ubiquitin homeostasis; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IDH3A_HUMAN             Reviewed;         366 AA.
AC   P50213; D3DW83; Q9H3X0;
DE   RecName: Full=Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial;
DE            EC=1.1.1.41;
DE   AltName: Full=Isocitric dehydrogenase subunit alpha;
DE   AltName: Full=NAD(+)-specific ICDH subunit alpha;
DE   Flags: Precursor;
GN   Name=IDH3A;
DR   GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   IDH3B_HUMAN             Reviewed;         385 AA.
AC   O43837; B2RDR1; D3DVX2; D3DVX3; O95106; Q5JXS8; Q9NQ06; Q9NQ07;
AC   Q9NUZ0; Q9UEX0; Q9UG99;
DE   RecName: Full=Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial;
DE            EC=1.1.1.41;
DE   AltName: Full=Isocitric dehydrogenase subunit beta;
DE   AltName: Full=NAD(+)-specific ICDH subunit beta;
DE   Flags: Precursor;
GN   Name=IDH3B;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; TAS:ProtInc.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006102; P:isocitrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006734; P:NADH metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   IDH3G_HUMAN             Reviewed;         393 AA.
AC   P51553; E9PDD5; Q9BUU5;
DE   RecName: Full=Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial;
DE            EC=1.1.1.41;
DE   AltName: Full=Isocitric dehydrogenase subunit gamma;
DE   AltName: Full=NAD(+)-specific ICDH subunit gamma;
DE   Flags: Precursor;
GN   Name=IDH3G;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   IDHC_HUMAN              Reviewed;         414 AA.
AC   O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8;
DE   RecName: Full=Isocitrate dehydrogenase [NADP] cytoplasmic;
DE            Short=IDH;
DE            EC=1.1.1.42;
DE   AltName: Full=Cytosolic NADP-isocitrate dehydrogenase;
DE   AltName: Full=IDP;
DE   AltName: Full=NADP(+)-specific ICDH;
DE   AltName: Full=Oxalosuccinate decarboxylase;
GN   Name=IDH1; Synonyms=PICD;
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:Ensembl.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006102; P:isocitrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006740; P:NADPH regeneration; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
//
ID   IDHP_HUMAN              Reviewed;         452 AA.
AC   P48735; B2R6L6; Q96GT3;
DE   RecName: Full=Isocitrate dehydrogenase [NADP], mitochondrial;
DE            Short=IDH;
DE            EC=1.1.1.42;
DE   AltName: Full=ICD-M;
DE   AltName: Full=IDP;
DE   AltName: Full=NADP(+)-specific ICDH;
DE   AltName: Full=Oxalosuccinate decarboxylase;
DE   Flags: Precursor;
GN   Name=IDH2;
DR   GO; GO:0004450; F:isocitrate dehydrogenase (NADP+) activity; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006102; P:isocitrate metabolic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   IDI1_HUMAN              Reviewed;         227 AA.
AC   Q13907; B4E155; Q32Q13; Q53GQ6; Q86U81; Q8WUX8; Q96IZ4; Q9BQ74;
DE   RecName: Full=Isopentenyl-diphosphate Delta-isomerase 1;
DE            EC=5.3.3.2;
DE   AltName: Full=Isopentenyl pyrophosphate isomerase 1;
DE            Short=IPP isomerase 1;
DE            Short=IPPI1;
GN   Name=IDI1;
DR   GuidetoPHARMACOLOGY; 646; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IDI2_HUMAN              Reviewed;         227 AA.
AC   Q9BXS1;
DE   RecName: Full=Isopentenyl-diphosphate delta-isomerase 2;
DE            EC=5.3.3.2;
DE   AltName: Full=Isopentenyl pyrophosphate isomerase 2;
DE            Short=IPP isomerase 2;
DE            Short=IPPI2;
GN   Name=IDI2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0050992; P:dimethylallyl diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046490; P:isopentenyl diphosphate metabolic process; IDA:MGI.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IDLC_HUMAN              Reviewed;         258 AA.
AC   O14645; A8K387; Q05BL9; Q5HYE2; Q5TGH0; Q7L0I5;
DE   RecName: Full=Axonemal dynein light intermediate polypeptide 1;
DE   AltName: Full=Inner dynein arm light chain, axonemal;
DE   AltName: Full=hp28;
GN   Name=DNALI1;
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   IDS_HUMAN               Reviewed;         550 AA.
AC   P22304; D3DWT4; Q14604; Q9BRM3;
DE   RecName: Full=Iduronate 2-sulfatase;
DE            EC=3.1.6.13;
DE   AltName: Full=Alpha-L-iduronate sulfate sulfatase;
DE            Short=Idursulfase;
DE   Contains:
DE     RecName: Full=Iduronate 2-sulfatase 42 kDa chain;
DE   Contains:
DE     RecName: Full=Iduronate 2-sulfatase 14 kDa chain;
DE   Flags: Precursor;
GN   Name=IDS; Synonyms=SIDS;
DR   GO; GO:0004423; F:iduronate-2-sulfatase activity; TAS:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IDUA_HUMAN              Reviewed;         653 AA.
AC   P35475;
DE   RecName: Full=Alpha-L-iduronidase;
DE            EC=3.2.1.76;
DE   Flags: Precursor;
GN   Name=IDUA;
DR   GO; GO:0003940; F:L-iduronidase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0048878; P:chemical homeostasis; IEA:Ensembl.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030209; P:dermatan sulfate catabolic process; IDA:UniProtKB.
DR   GO; GO:0005984; P:disaccharide metabolic process; TAS:ProtInc.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IER5L_HUMAN             Reviewed;         404 AA.
AC   Q5T953; Q6P3E2;
DE   RecName: Full=Immediate early response gene 5-like protein;
GN   Name=IER5L;
//
ID   IER2_HUMAN              Reviewed;         223 AA.
AC   Q9BTL4; Q03827; Q2TAZ2;
DE   RecName: Full=Immediate early response gene 2 protein;
DE   AltName: Full=Protein ETR101;
GN   Name=IER2; Synonyms=ETR101;
//
ID   IER5_HUMAN              Reviewed;         327 AA.
AC   Q5VY09; B2RBV3; Q8WY68; Q9NY49; Q9NZP9;
DE   RecName: Full=Immediate early response gene 5 protein;
GN   Name=IER5; ORFNames=PP4583, SBBI48;
//
ID   IEX1_HUMAN              Reviewed;         156 AA.
AC   P46695; Q5SU30; Q92691; Q93044;
DE   RecName: Full=Radiation-inducible immediate-early gene IEX-1;
DE   AltName: Full=Differentiation-dependent gene 2 protein;
DE            Short=Protein DIF-2;
DE   AltName: Full=Immediate early protein GLY96;
DE   AltName: Full=Immediate early response 3 protein;
DE   AltName: Full=PACAP-responsive gene 1 protein;
DE            Short=Protein PRG1;
GN   Name=IER3; Synonyms=DIF2, IEX1, PRG1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0045820; P:negative regulation of glycolytic process; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0003085; P:negative regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006282; P:regulation of DNA repair; IEA:Ensembl.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:2001020; P:regulation of response to DNA damage stimulus; IMP:MGI.
DR   GO; GO:0001562; P:response to protozoan; IEA:Ensembl.
//
ID   IF122_HUMAN             Reviewed;        1241 AA.
AC   Q9HBG6; G3XAB1; Q53G36; Q9BTB9; Q9BTY4; Q9HAT9; Q9HBG5; Q9UF80;
DE   RecName: Full=Intraflagellar transport protein 122 homolog;
DE   AltName: Full=WD repeat-containing protein 10;
DE   AltName: Full=WD repeat-containing protein 140;
GN   Name=IFT122; Synonyms=SPG, WDR10, WDR140;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010172; P:embryonic body morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035050; P:embryonic heart tube development; ISS:UniProtKB.
DR   GO; GO:0035721; P:intraciliary retrograde transport; ISS:UniProtKB.
DR   GO; GO:0060173; P:limb development; ISS:UniProtKB.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
//
ID   IF140_HUMAN             Reviewed;        1462 AA.
AC   Q96RY7; A2A2A8; D3DU75; O60332;
DE   RecName: Full=Intraflagellar transport protein 140 homolog;
DE   AltName: Full=WD and tetratricopeptide repeats protein 2;
GN   Name=IFT140; Synonyms=KIAA0590, WDTC2;
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0061512; P:protein localization to cilium; IMP:UniProt.
DR   GO; GO:1902017; P:regulation of cilium assembly; IMP:UniProt.
DR   GO; GO:0072001; P:renal system development; IMP:UniProt.
DR   GO; GO:0060041; P:retina development in camera-type eye; IMP:UniProt.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IMP:UniProt.
//
ID   IF16_HUMAN              Reviewed;         785 AA.
AC   Q16666; B4DJT8; H3BLV7; Q59GX0; Q5T3W7; Q5T3W8; Q5T3X0; Q5T3X1;
AC   Q5T3X2; Q8N9E5; Q8NEQ7; Q96AJ5; Q9UH78;
DE   RecName: Full=Gamma-interferon-inducible protein 16;
DE            Short=Ifi-16;
DE   AltName: Full=Interferon-inducible myeloid differentiation transcriptional activator;
GN   Name=IFI16; Synonyms=IFNGIP1;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0002218; P:activation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:MGI.
DR   GO; GO:0030224; P:monocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; NAS:UniProtKB.
DR   GO; GO:2000117; P:negative regulation of cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045824; P:negative regulation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; TAS:UniProtKB.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0010506; P:regulation of autophagy; IEP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IF172_HUMAN             Reviewed;        1749 AA.
AC   Q9UG01; A5PKZ0; B2RNU5; Q86X44; Q96HW4; Q9UFJ9; Q9ULP1;
DE   RecName: Full=Intraflagellar transport protein 172 homolog;
GN   Name=IFT172; Synonyms=KIAA1179;
DR   GO; GO:0042384; P:cilium assembly; IDA:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
//
ID   IF1AX_HUMAN             Reviewed;         144 AA.
AC   P47813; B2R5U5; Q0VGC2; Q5JPS5; Q5JPS6;
DE   RecName: Full=Eukaryotic translation initiation factor 1A, X-chromosomal;
DE            Short=eIF-1A X isoform;
DE   AltName: Full=Eukaryotic translation initiation factor 4C;
DE            Short=eIF-4C;
GN   Name=EIF1AX; Synonyms=EIF1A, EIF4C;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   IF1AY_HUMAN             Reviewed;         144 AA.
AC   O14602; Q9BS77;
DE   RecName: Full=Eukaryotic translation initiation factor 1A, Y-chromosomal;
DE            Short=eIF-1A Y isoform;
DE   AltName: Full=Eukaryotic translation initiation factor 4C;
DE            Short=eIF-4C;
GN   Name=EIF1AY;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
//
ID   IF2A_HUMAN              Reviewed;         315 AA.
AC   P05198;
DE   RecName: Full=Eukaryotic translation initiation factor 2 subunit 1;
DE   AltName: Full=Eukaryotic translation initiation factor 2 subunit alpha;
DE            Short=eIF-2-alpha;
DE            Short=eIF-2A;
DE            Short=eIF-2alpha;
GN   Name=EIF2S1; Synonyms=EIF2A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0043558; P:regulation of translational initiation in response to stress; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   IF2B1_HUMAN             Reviewed;         577 AA.
AC   Q9NZI8; C9JT33;
DE   RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 1;
DE            Short=IGF2 mRNA-binding protein 1;
DE            Short=IMP-1;
DE            Short=IMP1;
DE   AltName: Full=Coding region determinant-binding protein;
DE            Short=CRD-BP;
DE   AltName: Full=IGF-II mRNA-binding protein 1;
DE   AltName: Full=VICKZ family member 1;
DE   AltName: Full=Zipcode-binding protein 1;
DE            Short=ZBP-1;
GN   Name=IGF2BP1; Synonyms=CRDBP, VICKZ1, ZBP1;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IDA:BHF-UCL.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045182; F:translation regulator activity; IDA:BHF-UCL.
DR   GO; GO:0070934; P:CRD-mediated mRNA stabilization; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:BHF-UCL.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0010610; P:regulation of mRNA stability involved in response to stress; IMP:UniProtKB.
//
ID   IF2B2_HUMAN             Reviewed;         599 AA.
AC   Q9Y6M1; A0A4Z0; B3FTN2; B3FTN3; B3FTN4;
DE   RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 2;
DE            Short=IGF2 mRNA-binding protein 2;
DE            Short=IMP-2;
DE   AltName: Full=Hepatocellular carcinoma autoantigen p62;
DE   AltName: Full=IGF-II mRNA-binding protein 2;
DE   AltName: Full=VICKZ family member 2;
GN   Name=IGF2BP2; Synonyms=IMP2, VICKZ2;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IDA:BHF-UCL.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045182; F:translation regulator activity; ISS:BHF-UCL.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:BHF-UCL.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; IC:BHF-UCL.
//
ID   IF2B3_HUMAN             Reviewed;         579 AA.
AC   O00425; A0A4Z5; Q63HM0; Q6MZZ2; Q86VB1;
DE   RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 3;
DE            Short=IGF2 mRNA-binding protein 3;
DE            Short=IMP-3;
DE   AltName: Full=IGF-II mRNA-binding protein 3;
DE   AltName: Full=KH domain-containing protein overexpressed in cancer;
DE            Short=hKOC;
DE   AltName: Full=VICKZ family member 3;
GN   Name=IGF2BP3; Synonyms=IMP3, KOC1, VICKZ3;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IDA:BHF-UCL.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0045182; F:translation regulator activity; ISS:BHF-UCL.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:BHF-UCL.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   IF2B_HUMAN              Reviewed;         333 AA.
AC   P20042; Q9BVU0; Q9UJE4;
DE   RecName: Full=Eukaryotic translation initiation factor 2 subunit 2;
DE   AltName: Full=Eukaryotic translation initiation factor 2 subunit beta;
DE            Short=eIF-2-beta;
GN   Name=EIF2S2; Synonyms=EIF2B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0002176; P:male germ cell proliferation; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   IF2GL_HUMAN             Reviewed;         472 AA.
AC   Q2VIR3; Q5I0X0; Q6KF84;
DE   RecName: Full=Putative eukaryotic translation initiation factor 2 subunit 3-like protein;
DE   AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma A;
DE            Short=eIF-2-gamma A;
DE            Short=eIF-2gA;
GN   Name=EIF2S3L;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
//
ID   IF2G_HUMAN              Reviewed;         472 AA.
AC   P41091; B5BTZ4;
DE   RecName: Full=Eukaryotic translation initiation factor 2 subunit 3;
DE   AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma X;
DE            Short=eIF-2-gamma X;
DE            Short=eIF-2gX;
GN   Name=EIF2S3; Synonyms=EIF2G;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IDA:UniProtKB.
//
ID   IF2M_HUMAN              Reviewed;         727 AA.
AC   P46199; D6W5D0;
DE   RecName: Full=Translation initiation factor IF-2, mitochondrial;
DE            Short=IF-2(Mt);
DE            Short=IF-2Mt;
DE            Short=IF2(mt);
DE   Flags: Precursor;
GN   Name=MTIF2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; ISS:HGNC.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; ISS:HGNC.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001732; P:formation of translation initiation complex; ISS:BHF-UCL.
DR   GO; GO:0006446; P:regulation of translational initiation; ISS:HGNC.
DR   GO; GO:0032790; P:ribosome disassembly; ISS:BHF-UCL.
//
ID   IF2P_HUMAN              Reviewed;        1220 AA.
AC   O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7;
DE   RecName: Full=Eukaryotic translation initiation factor 5B;
DE            Short=eIF-5B;
DE   AltName: Full=Translation initiation factor IF-2;
GN   Name=EIF5B; Synonyms=IF2, KIAA0741;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   IF3M_HUMAN              Reviewed;         278 AA.
AC   Q9H2K0; Q05BL8; Q5W0V0; Q86X68;
DE   RecName: Full=Translation initiation factor IF-3, mitochondrial;
DE            Short=IF-3(Mt);
DE            Short=IF-3Mt;
DE            Short=IF3(mt);
DE            Short=IF3mt;
DE   Flags: Precursor;
GN   Name=MTIF3; ORFNames=DC38;
DR   GO; GO:0043024; F:ribosomal small subunit binding; IDA:BHF-UCL.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; IDA:BHF-UCL.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001732; P:formation of translation initiation complex; IDA:BHF-UCL.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:BHF-UCL.
DR   GO; GO:0032790; P:ribosome disassembly; IDA:BHF-UCL.
//
ID   IF44L_HUMAN             Reviewed;         452 AA.
AC   Q53G44; Q86TE1; Q96B64; Q99984;
DE   RecName: Full=Interferon-induced protein 44-like;
GN   Name=IFI44L; Synonyms=C1orf29; ORFNames=GS3686;
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
//
ID   IF4A1_HUMAN             Reviewed;         406 AA.
AC   P60842; B2R6L8; D3DTP9; J3QLC4; P04765; Q5U018; Q61516;
DE   RecName: Full=Eukaryotic initiation factor 4A-I;
DE            Short=eIF-4A-I;
DE            Short=eIF4A-I;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase eIF4A-1;
GN   Name=EIF4A1; Synonyms=DDX2A, EIF4A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0004386; F:helicase activity; TAS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000339; F:RNA cap binding; TAS:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IF4A2_HUMAN             Reviewed;         407 AA.
AC   Q14240; D3DNU9; Q53XJ6; Q96B90; Q96EA8;
DE   RecName: Full=Eukaryotic initiation factor 4A-II;
DE            Short=eIF-4A-II;
DE            Short=eIF4A-II;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase eIF4A-2;
GN   Name=EIF4A2; Synonyms=DDX2B, EIF4F;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003743; F:translation initiation factor activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IF4A3_HUMAN             Reviewed;         411 AA.
AC   P38919; Q15033; Q6IBQ2; Q96A18;
DE   RecName: Full=Eukaryotic initiation factor 4A-III;
DE            Short=eIF-4A-III;
DE            Short=eIF4A-III;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase DDX48;
DE   AltName: Full=ATP-dependent RNA helicase eIF4A-3;
DE   AltName: Full=DEAD box protein 48;
DE   AltName: Full=Eukaryotic initiation factor 4A-like NUK-34;
DE   AltName: Full=Eukaryotic translation initiation factor 4A isoform 3;
DE   AltName: Full=Nuclear matrix protein 265;
DE            Short=NMP 265;
DE            Short=hNMP 265;
DE   Contains:
DE     RecName: Full=Eukaryotic initiation factor 4A-III, N-terminally processed;
GN   Name=EIF4A3; Synonyms=DDX48, KIAA0111;
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:HGNC.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0008143; F:poly(A) binding; IDA:HGNC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:HGNC.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   IF4B_HUMAN              Reviewed;         611 AA.
AC   P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5;
DE   RecName: Full=Eukaryotic translation initiation factor 4B;
DE            Short=eIF-4B;
GN   Name=EIF4B;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   IF4E2_HUMAN             Reviewed;         245 AA.
AC   O60573; B8ZZJ9; O75349;
DE   RecName: Full=Eukaryotic translation initiation factor 4E type 2;
DE            Short=eIF-4E type 2;
DE            Short=eIF4E type 2;
DE   AltName: Full=Eukaryotic translation initiation factor 4E homologous protein;
DE   AltName: Full=Eukaryotic translation initiation factor 4E-like 3;
DE   AltName: Full=eIF4E-like protein 4E-LP;
DE   AltName: Full=mRNA cap-binding protein 4EHP;
DE   AltName: Full=mRNA cap-binding protein type 3;
GN   Name=EIF4E2; Synonyms=EIF4EL3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000339; F:RNA cap binding; TAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IMP:MGI.
//
ID   IF4E3_HUMAN             Reviewed;         224 AA.
AC   Q8N5X7; B2R963; Q6NUT1;
DE   RecName: Full=Eukaryotic translation initiation factor 4E type 3;
DE            Short=eIF-4E type 3;
DE            Short=eIF-4E3;
DE            Short=eIF4E type 3;
DE            Short=eIF4E-3;
GN   Name=EIF4E3;
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   IF4E_HUMAN              Reviewed;         217 AA.
AC   P06730; B7Z6V1; D6RCQ6; Q96E95;
DE   RecName: Full=Eukaryotic translation initiation factor 4E;
DE            Short=eIF-4E;
DE            Short=eIF4E;
DE   AltName: Full=eIF-4F 25 kDa subunit;
DE   AltName: Full=mRNA cap-binding protein;
GN   Name=EIF4E; Synonyms=EIF4EL1, EIF4F;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000339; F:RNA cap binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IF4G1_HUMAN             Reviewed;        1599 AA.
AC   Q04637; D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; O43177; O95066;
AC   Q5HYG0; Q6ZN21; Q8N102;
DE   RecName: Full=Eukaryotic translation initiation factor 4 gamma 1;
DE            Short=eIF-4-gamma 1;
DE            Short=eIF-4G 1;
DE            Short=eIF-4G1;
DE   AltName: Full=p220;
GN   Name=EIF4G1; Synonyms=EIF4F, EIF4G, EIF4GI;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; TAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IF4G2_HUMAN             Reviewed;         907 AA.
AC   P78344; O60877; P78404; Q0VH00; Q0VH01; Q2NKW9; Q49A79; Q53EU1;
AC   Q58EZ2; Q8NI71; Q96C16;
DE   RecName: Full=Eukaryotic translation initiation factor 4 gamma 2;
DE            Short=eIF-4-gamma 2;
DE            Short=eIF-4G 2;
DE            Short=eIF4G 2;
DE   AltName: Full=Death-associated protein 5;
DE            Short=DAP-5;
DE   AltName: Full=p97;
GN   Name=EIF4G2; Synonyms=DAP5; ORFNames=OK/SW-cl.75;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.
//
ID   IF4G3_HUMAN             Reviewed;        1585 AA.
AC   O43432; B9EGQ7; Q15597; Q504Z1; Q5SWC3; Q8NEN1;
DE   RecName: Full=Eukaryotic translation initiation factor 4 gamma 3;
DE            Short=eIF-4-gamma 3;
DE            Short=eIF-4G 3;
DE            Short=eIF4G 3;
DE   AltName: Full=eIF-4-gamma II;
DE            Short=eIF4GII;
GN   Name=EIF4G3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000339; F:RNA cap binding; TAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060903; P:positive regulation of meiosis I; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IF4H_HUMAN              Reviewed;         248 AA.
AC   Q15056; A8K3R1; D3DXF6; D3DXF8;
DE   RecName: Full=Eukaryotic translation initiation factor 4H;
DE            Short=eIF-4H;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 1 protein;
GN   Name=EIF4H; Synonyms=KIAA0038, WBSCR1, WSCR1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0019953; P:sexual reproduction; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IF5A1_HUMAN             Reviewed;         154 AA.
AC   P63241; A8K9A0; D3DTP2; P10159; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2;
DE   RecName: Full=Eukaryotic translation initiation factor 5A-1;
DE            Short=eIF-5A-1;
DE            Short=eIF-5A1;
DE   AltName: Full=Eukaryotic initiation factor 5A isoform 1;
DE            Short=eIF-5A;
DE   AltName: Full=Rev-binding factor;
DE   AltName: Full=eIF-4D;
GN   Name=EIF5A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003746; F:translation elongation factor activity; ISS:UniProtKB.
DR   GO; GO:0017070; F:U6 snRNA binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IMP:UniProtKB.
DR   GO; GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:UniProtKB.
DR   GO; GO:0045901; P:positive regulation of translational elongation; ISS:UniProtKB.
DR   GO; GO:0045905; P:positive regulation of translational termination; IEA:InterPro.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006611; P:protein export from nucleus; IMP:UniProtKB.
DR   GO; GO:0006452; P:translational frameshifting; IEA:InterPro.
//
ID   IF5A2_HUMAN             Reviewed;         153 AA.
AC   Q9GZV4; B2R4V5;
DE   RecName: Full=Eukaryotic translation initiation factor 5A-2;
DE            Short=eIF-5A-2;
DE            Short=eIF-5A2;
DE   AltName: Full=Eukaryotic initiation factor 5A isoform 2;
GN   Name=EIF5A2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; TAS:Reactome.
DR   GO; GO:0010509; P:polyamine homeostasis; NAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:UniProtKB.
DR   GO; GO:0045901; P:positive regulation of translational elongation; IEA:InterPro.
DR   GO; GO:0045905; P:positive regulation of translational termination; IEA:InterPro.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
DR   GO; GO:0006452; P:translational frameshifting; IEA:InterPro.
//
ID   IF5AL_HUMAN             Reviewed;         154 AA.
AC   Q6IS14;
DE   RecName: Full=Eukaryotic translation initiation factor 5A-1-like;
DE            Short=eIF-5A-1-like;
DE            Short=eIF-5A1-like;
DE   AltName: Full=Eukaryotic initiation factor 5A isoform 1-like;
GN   Name=EIF5AL1;
DR   GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; IEA:InterPro.
DR   GO; GO:0045901; P:positive regulation of translational elongation; IEA:InterPro.
DR   GO; GO:0045905; P:positive regulation of translational termination; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006452; P:translational frameshifting; IEA:InterPro.
//
ID   IF5_HUMAN               Reviewed;         431 AA.
AC   P55010; Q53XB3; Q9H5N2; Q9UG48;
DE   RecName: Full=Eukaryotic translation initiation factor 5;
DE            Short=eIF-5;
GN   Name=EIF5;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0006446; P:regulation of translational initiation; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; NAS:UniProtKB.
//
ID   IF6_HUMAN               Reviewed;         245 AA.
AC   P56537; B7ZBG9; Q6IBN8; Q96TD5;
DE   RecName: Full=Eukaryotic translation initiation factor 6;
DE            Short=eIF-6;
DE   AltName: Full=B(2)GCN homolog;
DE   AltName: Full=B4 integrin interactor;
DE   AltName: Full=CAB;
DE   AltName: Full=p27(BBP);
GN   Name=EIF6; Synonyms=EIF3A, ITGB4BP; ORFNames=OK/SW-cl.27;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0042256; P:mature ribosome assembly; IMP:UniProtKB.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000054; P:ribosomal subunit export from nucleus; IEA:UniProtKB-HAMAP.
//
ID   IFFO1_HUMAN             Reviewed;         559 AA.
AC   Q0D2I5; Q24JT6; Q7L5J9; Q7Z5X4; Q9BQ46;
DE   RecName: Full=Intermediate filament family orphan 1;
DE   AltName: Full=Tumor antigen HOM-TES-103;
GN   Name=IFFO1; Synonyms=IFFO;
//
ID   IFFO2_HUMAN             Reviewed;         517 AA.
AC   Q5TF58; Q9H7K0;
DE   RecName: Full=Intermediate filament family orphan 2;
GN   Name=IFFO2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   IFI27_HUMAN             Reviewed;         119 AA.
AC   P40305; Q53YA6; Q6IEC1; Q96BK3;
DE   RecName: Full=Interferon alpha-inducible protein 27, mitochondrial;
DE            Short=p27;
DE   AltName: Full=Interferon alpha-induced 11.5 kDa protein;
DE   AltName: Full=Interferon-stimulated gene 12a protein;
DE            Short=ISG12(a);
DE   Flags: Precursor;
GN   Name=IFI27;
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFG15_HUMAN             Reviewed;         131 AA.
AC   Q9H496; Q05BU2;
DE   RecName: Full=Torsin-1A-interacting protein 2, isoform IFRG15;
DE   AltName: Full=15 kDa interferon-responsive protein;
DE            Short=IFRG15;
GN   Name=TOR1AIP2; Synonyms=IFRG15;
//
ID   IFI44_HUMAN             Reviewed;         444 AA.
AC   Q8TCB0; D3DQ80; Q14496;
DE   RecName: Full=Interferon-induced protein 44;
DE            Short=p44;
DE   AltName: Full=Microtubule-associated protein 44;
GN   Name=IFI44; Synonyms=MTAP44;
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
//
ID   IFI6_HUMAN              Reviewed;         130 AA.
AC   P09912; Q13141; Q13142; Q5VVR2; Q5VVR3; Q6IE95; Q969M8;
DE   RecName: Full=Interferon alpha-inducible protein 6;
DE   AltName: Full=Interferon-induced protein 6-16;
DE            Short=Ifi-6-16;
DE   Flags: Precursor;
GN   Name=IFI6; Synonyms=G1P3;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:HGNC.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:0051902; P:negative regulation of mitochondrial depolarization; IMP:HGNC.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IMP:HGNC.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFIH1_HUMAN             Reviewed;        1025 AA.
AC   Q9BYX4; Q2NKL6; Q6DC96; Q86X56; Q96MX8; Q9H3G6;
DE   RecName: Full=Interferon-induced helicase C domain-containing protein 1;
DE            EC=3.6.4.13;
DE   AltName: Full=Clinically amyopathic dermatomyositis autoantigen 140 kDa;
DE            Short=CADM-140 autoantigen;
DE   AltName: Full=Helicase with 2 CARD domains;
DE            Short=Helicard;
DE   AltName: Full=Interferon-induced with helicase C domain protein 1;
DE   AltName: Full=Melanoma differentiation-associated protein 5;
DE            Short=MDA-5;
DE   AltName: Full=Murabutide down-regulated protein;
DE   AltName: Full=RIG-I-like receptor 2;
DE            Short=RLR-2;
DE   AltName: Full=RNA helicase-DEAD box protein 116;
GN   Name=IFIH1; Synonyms=MDA5, RH116;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0039528; P:cytoplasmic pattern recognition receptor signaling pathway in response to virus; TAS:UniProtKB.
DR   GO; GO:0009597; P:detection of virus; TAS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IFIT1_HUMAN             Reviewed;         478 AA.
AC   P09914; B3KS50; D3DR31; Q5T7J1; Q96QM5;
DE   RecName: Full=Interferon-induced protein with tetratricopeptide repeats 1;
DE            Short=IFIT-1;
DE   AltName: Full=Interferon-induced 56 kDa protein;
DE            Short=IFI-56K;
DE            Short=P56;
GN   Name=IFIT1; Synonyms=G10P1, IFI56, IFNAI1, ISG56;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IDA:BHF-UCL.
DR   GO; GO:0071357; P:cellular response to type I interferon; IDA:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0019060; P:intracellular transport of viral protein in host cell; IDA:BHF-UCL.
DR   GO; GO:0050689; P:negative regulation of defense response to virus by host; IDA:BHF-UCL.
DR   GO; GO:0051097; P:negative regulation of helicase activity; IDA:BHF-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFIT2_HUMAN             Reviewed;         472 AA.
AC   P09913; Q5T767;
DE   RecName: Full=Interferon-induced protein with tetratricopeptide repeats 2;
DE            Short=IFIT-2;
DE   AltName: Full=ISG-54 K;
DE   AltName: Full=Interferon-induced 54 kDa protein;
DE            Short=IFI-54K;
DE            Short=P54;
GN   Name=IFIT2; Synonyms=CIG-42, G10P2, IFI54, ISG54;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; TAS:UniProtKB.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFIT3_HUMAN             Reviewed;         490 AA.
AC   O14879; Q99634; Q9BSK7;
DE   RecName: Full=Interferon-induced protein with tetratricopeptide repeats 3;
DE            Short=IFIT-3;
DE   AltName: Full=CIG49;
DE   AltName: Full=ISG-60;
DE   AltName: Full=Interferon-induced 60 kDa protein;
DE            Short=IFI-60K;
DE   AltName: Full=Interferon-induced protein with tetratricopeptide repeats 4;
DE            Short=IFIT-4;
DE   AltName: Full=Retinoic acid-induced gene G protein;
DE            Short=P60;
DE            Short=RIG-G;
GN   Name=IFIT3; Synonyms=CIG-49, IFI60, IFIT4, ISG60;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFIT5_HUMAN             Reviewed;         482 AA.
AC   Q13325; B2R5X9; Q5T7I9; Q6IAX3;
DE   RecName: Full=Interferon-induced protein with tetratricopeptide repeats 5;
DE            Short=IFIT-5;
DE   AltName: Full=Interferon-induced 58 kDa protein;
DE   AltName: Full=Retinoic acid- and interferon-inducible 58 kDa protein;
DE            Short=P58;
GN   Name=IFIT5; Synonyms=ISG58, RI58;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   IFIX_HUMAN              Reviewed;         492 AA.
AC   Q6K0P9; Q5T3W6; Q6K0P6; Q6K0P7; Q6K0P8; Q8WW65;
DE   RecName: Full=Pyrin and HIN domain-containing protein 1;
DE   AltName: Full=Interferon-inducible protein X;
GN   Name=PYHIN1; Synonyms=IFIX;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   IFM10_HUMAN             Reviewed;         228 AA.
AC   A6NMD0; A6NEU7;
DE   RecName: Full=Interferon-induced transmembrane protein 10;
DE   AltName: Full=Dispanin subfamily A member 3;
DE            Short=DSPA3;
GN   Name=IFITM10;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   IFM1_HUMAN              Reviewed;         125 AA.
AC   P13164; Q15322; Q53XZ0;
DE   RecName: Full=Interferon-induced transmembrane protein 1;
DE   AltName: Full=Dispanin subfamily A member 2a;
DE            Short=DSPA2a;
DE   AltName: Full=Interferon-induced protein 17;
DE   AltName: Full=Interferon-inducible protein 9-27;
DE   AltName: Full=Leu-13 antigen;
DE   AltName: CD_antigen=CD225;
GN   Name=IFITM1; Synonyms=CD225, IFI17;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0035456; P:response to interferon-beta; IDA:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFM3_HUMAN              Reviewed;         133 AA.
AC   Q01628; Q53Y76; Q96HK8; Q96J15;
DE   RecName: Full=Interferon-induced transmembrane protein 3;
DE   AltName: Full=Dispanin subfamily A member 2b;
DE            Short=DSPA2b;
DE   AltName: Full=Interferon-inducible protein 1-8U;
GN   Name=IFITM3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0035456; P:response to interferon-beta; IDA:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFM2_HUMAN              Reviewed;         132 AA.
AC   Q01629; Q6FH82; Q96DA8;
DE   RecName: Full=Interferon-induced transmembrane protein 2;
DE   AltName: Full=Dispanin subfamily A member 2c;
DE            Short=DSPA2c;
DE   AltName: Full=Interferon-inducible protein 1-8D;
GN   Name=IFITM2;
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0035456; P:response to interferon-beta; IDA:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFM5_HUMAN              Reviewed;         132 AA.
AC   A6NNB3;
DE   RecName: Full=Interferon-induced transmembrane protein 5;
DE   AltName: Full=Bone-restricted interferon-induced transmembrane protein-like protein;
DE            Short=BRIL;
DE   AltName: Full=Dispanin subfamily A member 1;
DE            Short=DSPA1;
GN   Name=IFITM5;
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   IFN16_HUMAN             Reviewed;         189 AA.
AC   P05015; Q5VV12;
DE   RecName: Full=Interferon alpha-16;
DE            Short=IFN-alpha-16;
DE   AltName: Full=Interferon alpha-WA;
DE   Flags: Precursor;
GN   Name=IFNA16;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFN10_HUMAN             Reviewed;         189 AA.
AC   P01566; Q5VV13;
DE   RecName: Full=Interferon alpha-10;
DE            Short=IFN-alpha-10;
DE   AltName: Full=Interferon alpha-6L;
DE   AltName: Full=Interferon alpha-C;
DE            Short=LeIF C;
DE   Flags: Precursor;
GN   Name=IFNA10;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFN14_HUMAN             Reviewed;         189 AA.
AC   P01570; Q5VZ56; Q7M4S1;
DE   RecName: Full=Interferon alpha-14;
DE            Short=IFN-alpha-14;
DE   AltName: Full=Interferon alpha-H;
DE            Short=LeIF H;
DE   AltName: Full=Interferon lambda-2-H;
DE   Flags: Precursor;
GN   Name=IFNA14;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005126; F:cytokine receptor binding; TAS:ProtInc.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFN17_HUMAN             Reviewed;         189 AA.
AC   P01571; Q14639; Q4KMT4; Q5VZ53; Q7M4Q4;
DE   RecName: Full=Interferon alpha-17;
DE            Short=IFN-alpha-17;
DE   AltName: Full=Interferon alpha-88;
DE   AltName: Full=Interferon alpha-I';
DE            Short=LeIF I;
DE   AltName: Full=Interferon alpha-T;
DE   Flags: Precursor;
GN   Name=IFNA17;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFN21_HUMAN             Reviewed;         189 AA.
AC   P01568; Q14608; Q5VWD1; Q7M4Q4;
DE   RecName: Full=Interferon alpha-21;
DE            Short=IFN-alpha-21;
DE   AltName: Full=Interferon alpha-F;
DE            Short=LeIF F;
DE   Flags: Precursor;
GN   Name=IFNA21;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005126; F:cytokine receptor binding; TAS:ProtInc.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA1_HUMAN             Reviewed;         189 AA.
AC   P01562; D4Q9M8; Q14605; Q2M1L8; Q52LB8; Q5VYQ2; Q7M4Q1; Q8WZ68;
AC   Q9UMJ3;
DE   RecName: Full=Interferon alpha-1/13;
DE            Short=IFN-alpha-1/13;
DE   AltName: Full=Interferon alpha-D;
DE            Short=LeIF D;
DE   Flags: Precursor;
GN   Name=IFNA1;
GN   and
GN   Name=IFNA13;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA2_HUMAN             Reviewed;         188 AA.
AC   P01563; P01564; Q14606; Q96KI6;
DE   RecName: Full=Interferon alpha-2;
DE            Short=IFN-alpha-2;
DE   AltName: Full=Interferon alpha-A;
DE            Short=LeIF A;
DE   Flags: Precursor;
GN   Name=IFNA2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005132; F:type I interferon receptor binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2000666; P:negative regulation of interleukin-13 secretion; IDA:UniProtKB.
DR   GO; GO:2000663; P:negative regulation of interleukin-5 secretion; IDA:UniProtKB.
DR   GO; GO:0045581; P:negative regulation of T cell differentiation; IDA:UniProtKB.
DR   GO; GO:2000552; P:negative regulation of T-helper 2 cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA4_HUMAN             Reviewed;         189 AA.
AC   P05014; P13358; Q14CS4; Q5VV15;
DE   RecName: Full=Interferon alpha-4;
DE            Short=IFN-alpha-4;
DE   AltName: Full=Interferon alpha-4B;
DE   AltName: Full=Interferon alpha-76;
DE   AltName: Full=Interferon alpha-M1;
DE   Flags: Precursor;
GN   Name=IFNA4;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA5_HUMAN             Reviewed;         189 AA.
AC   P01569; Q52LX3;
DE   RecName: Full=Interferon alpha-5;
DE            Short=IFN-alpha-5;
DE   AltName: Full=Interferon alpha-61;
DE   AltName: Full=Interferon alpha-G;
DE            Short=LeIF G;
DE   Flags: Precursor;
GN   Name=IFNA5;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005126; F:cytokine receptor binding; TAS:ProtInc.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA6_HUMAN             Reviewed;         189 AA.
AC   P05013; Q5VYQ1;
DE   RecName: Full=Interferon alpha-6;
DE            Short=IFN-alpha-6;
DE   AltName: Full=Interferon alpha-54;
DE   AltName: Full=Interferon alpha-K;
DE            Short=LeIF K;
DE   Flags: Precursor;
GN   Name=IFNA6;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA7_HUMAN             Reviewed;         189 AA.
AC   P01567; Q14607; Q5VV14;
DE   RecName: Full=Interferon alpha-7;
DE            Short=IFN-alpha-7;
DE   AltName: Full=Interferon alpha-J;
DE            Short=LeIF J;
DE   AltName: Full=Interferon alpha-J1;
DE            Short=IFN-alpha-J1;
DE   Flags: Precursor;
GN   Name=IFNA7;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNA8_HUMAN             Reviewed;         189 AA.
AC   P32881; P01565; P09236; Q5VWV7; Q5VYQ3;
DE   RecName: Full=Interferon alpha-8;
DE            Short=IFN-alpha-8;
DE   AltName: Full=Interferon alpha-B;
DE            Short=LeIF B;
DE   AltName: Full=Interferon alpha-B2;
DE   Flags: Precursor;
GN   Name=IFNA8;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005126; F:cytokine receptor binding; TAS:ProtInc.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNB_HUMAN              Reviewed;         187 AA.
AC   P01574;
DE   RecName: Full=Interferon beta;
DE            Short=IFN-beta;
DE   AltName: Full=Fibroblast interferon;
DE   Flags: Precursor;
GN   Name=IFNB1; Synonyms=IFB, IFNB;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0005132; F:type I interferon receptor binding; NAS:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; IEA:Ensembl.
DR   GO; GO:0002312; P:B cell activation involved in immune response; IMP:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; TAS:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; TAS:BHF-UCL.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0045581; P:negative regulation of T cell differentiation; IDA:UniProtKB.
DR   GO; GO:2000552; P:negative regulation of T-helper 2 cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045089; P:positive regulation of innate immune response; NAS:UniProtKB.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IDA:MGI.
DR   GO; GO:0009615; P:response to virus; NAS:UniProtKB.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IFNE_HUMAN              Reviewed;         208 AA.
AC   Q86WN2;
DE   RecName: Full=Interferon epsilon;
DE            Short=IFN-epsilon;
DE   AltName: Full=Interferon epsilon-1;
DE   Flags: Precursor;
GN   Name=IFNE; Synonyms=IFNE1; ORFNames=UNQ360/PRO655;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
//
ID   IFNG_HUMAN              Reviewed;         166 AA.
AC   P01579; B5BU88; Q53ZV4;
DE   RecName: Full=Interferon gamma;
DE            Short=IFN-gamma;
DE   AltName: Full=Immune interferon;
DE   Flags: Precursor;
GN   Name=IFNG;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005133; F:interferon-gamma receptor binding; TAS:ProtInc.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IGI:MGI.
DR   GO; GO:0002302; P:CD8-positive, alpha-beta T cell differentiation involved in immune response; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071351; P:cellular response to interleukin-18; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0003340; P:negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0072308; P:negative regulation of metanephric nephron tubule epithelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0031642; P:negative regulation of myelination; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0001781; P:neutrophil apoptotic process; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0060559; P:positive regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060550; P:positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0060552; P:positive regulation of fructose 1,6-bisphosphate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IEA:Ensembl.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:UniProtKB.
DR   GO; GO:0032747; P:positive regulation of interleukin-23 production; IDA:BHF-UCL.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl.
DR   GO; GO:0051712; P:positive regulation of killing of cells of other organism; IDA:BHF-UCL.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; NAS:BHF-UCL.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2000309; P:positive regulation of tumor necrosis factor (ligand) superfamily member 11 production; IDA:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IDA:BHF-UCL.
DR   GO; GO:0060557; P:positive regulation of vitamin D biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IDA:MGI.
//
ID   IFNL1_HUMAN             Reviewed;         200 AA.
AC   Q8IU54; A0AV25; Q17R34;
DE   RecName: Full=Interferon lambda-1;
DE            Short=IFN-lambda-1;
DE   AltName: Full=Cytokine Zcyto21;
DE   AltName: Full=Interleukin-29;
DE            Short=IL-29;
DE   Flags: Precursor;
GN   Name=IFNL1; Synonyms=IL29, ZCYTO21;
DR   GO; GO:0032003; F:interleukin-28 receptor binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0032696; P:negative regulation of interleukin-13 production; IDA:UniProtKB.
DR   GO; GO:0032714; P:negative regulation of interleukin-5 production; IDA:UniProtKB.
DR   GO; GO:0043381; P:negative regulation of memory T cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045581; P:negative regulation of T cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0002829; P:negative regulation of type 2 immune response; IDA:UniProtKB.
DR   GO; GO:0050778; P:positive regulation of immune response; TAS:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB.
DR   GO; GO:0045345; P:positive regulation of MHC class I biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IDA:UniProtKB.
//
ID   IFNK_HUMAN              Reviewed;         207 AA.
AC   Q9P0W0; Q5T166;
DE   RecName: Full=Interferon kappa;
DE            Short=IFN-kappa;
DE   Flags: Precursor;
GN   Name=IFNK; ORFNames=UNQ6124/PRO20084;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005132; F:type I interferon receptor binding; IDA:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0045089; P:positive regulation of innate immune response; TAS:UniProtKB.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
//
ID   IFNL2_HUMAN             Reviewed;         200 AA.
AC   Q8IZJ0; Q45KQ8; Q6VN55; Q8IWL7;
DE   RecName: Full=Interferon lambda-2;
DE            Short=IFN-lambda-2;
DE   AltName: Full=Cytokine Zcyto20;
DE   AltName: Full=Interleukin-28A;
DE            Short=IL-28A;
DE   Flags: Precursor;
GN   Name=IFNL2; Synonyms=IL28A, ZCYTO20;
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0002385; P:mucosal immune response; ISS:UniProtKB.
//
ID   IFNL3_HUMAN             Reviewed;         196 AA.
AC   Q8IZI9; A2BDE1; Q6VN56; Q7Z4J3; Q8IWL6;
DE   RecName: Full=Interferon lambda-3;
DE            Short=IFN-lambda-3;
DE   AltName: Full=Cytokine Zcyto22;
DE   AltName: Full=Interleukin-28B;
DE            Short=IL-28B;
DE   AltName: Full=Interleukin-28C;
DE            Short=IL-28C;
DE   Flags: Precursor;
GN   Name=IFNL3; Synonyms=IL28B, IL28C, ZCYTO22;
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
//
ID   IFNL4_HUMAN             Reviewed;         179 AA.
AC   K9M1U5; K9M1A5; K9M269; K9M2P7;
DE   RecName: Full=Interferon lambda-4;
DE            Short=IFN-lambda-4;
DE   Flags: Precursor;
GN   Name=IFNL4;
DR   GO; GO:0005125; F:cytokine activity; IMP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0042508; P:tyrosine phosphorylation of Stat1 protein; IMP:UniProtKB.
DR   GO; GO:0042502; P:tyrosine phosphorylation of Stat2 protein; IDA:UniProtKB.
//
ID   IFNW1_HUMAN             Reviewed;         195 AA.
AC   P05000; Q13168; Q5U802; Q5VWD0; Q7M4P5;
DE   RecName: Full=Interferon omega-1;
DE   AltName: Full=Interferon alpha-II-1;
DE   Flags: Precursor;
GN   Name=IFNW1;
DR   GO; GO:0005125; F:cytokine activity; IBA:RefGenome.
DR   GO; GO:0005126; F:cytokine receptor binding; TAS:ProtInc.
DR   GO; GO:0005132; F:type I interferon receptor binding; IBA:RefGenome.
DR   GO; GO:0002250; P:adaptive immune response; IBA:RefGenome.
DR   GO; GO:0030183; P:B cell differentiation; IBA:RefGenome.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006959; P:humoral immune response; IBA:RefGenome.
DR   GO; GO:0045087; P:innate immune response; IBA:RefGenome.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IBA:RefGenome.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IBA:RefGenome.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IBA:RefGenome.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IBA:RefGenome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IBA:RefGenome.
//
ID   IFRD1_HUMAN             Reviewed;         451 AA.
AC   O00458; B7Z5G1; O75234; Q5U013; Q9BVE4;
DE   RecName: Full=Interferon-related developmental regulator 1;
DE   AltName: Full=Nerve growth factor-inducible protein PC4;
GN   Name=IFRD1;
DR   GO; GO:0007527; P:adult somatic muscle development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007518; P:myoblast fate determination; TAS:ProtInc.
//
ID   IFRD2_HUMAN             Reviewed;         506 AA.
AC   Q12894; Q9BVB4;
DE   RecName: Full=Interferon-related developmental regulator 2;
DE   AltName: Full=Protein SKMC15;
GN   Name=IFRD2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   IFT20_HUMAN             Reviewed;         132 AA.
AC   Q8IY31; J3QL09; Q5GLZ2; Q9BUG5;
DE   RecName: Full=Intraflagellar transport protein 20 homolog;
DE            Short=hIFT20;
GN   Name=IFT20;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IMP:MGI.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IMP:MGI.
DR   GO; GO:2000785; P:regulation of autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:1902017; P:regulation of cilium assembly; ISS:UniProtKB.
//
ID   IFT1B_HUMAN             Reviewed;         474 AA.
AC   Q5T764; A7E245;
DE   RecName: Full=Interferon-induced protein with tetratricopeptide repeats 1B;
DE   AltName: Full=Interferon-induced protein with tetratricopeptide repeats 1-like protein;
GN   Name=IFIT1B; Synonyms=IFIT1L;
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IEA:InterPro.
DR   GO; GO:0071357; P:cellular response to type I interferon; IEA:InterPro.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:InterPro.
DR   GO; GO:0009615; P:response to virus; IEA:InterPro.
//
ID   IFT22_HUMAN             Reviewed;         185 AA.
AC   Q9H7X7; Q49AG1; Q69YV5; Q9BSW4;
DE   RecName: Full=Intraflagellar transport protein 22 homolog;
DE   AltName: Full=Rab-like protein 5;
GN   Name=IFT22; Synonyms=RABL5;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   IFT25_HUMAN             Reviewed;         144 AA.
AC   Q9Y547; A6NG57; D3DQ45; Q9Y684;
DE   RecName: Full=Intraflagellar transport protein 25 homolog;
DE   AltName: Full=Heat shock protein beta-11;
DE            Short=Hspb11;
DE   AltName: Full=Placental protein 25;
DE            Short=PP25;
GN   Name=HSPB11; Synonyms=C1orf41, IFT25; ORFNames=HSPC034;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
//
ID   IFT27_HUMAN             Reviewed;         186 AA.
AC   Q9BW83; O60897;
DE   RecName: Full=Intraflagellar transport protein 27 homolog;
DE   AltName: Full=Putative GTP-binding protein RAY-like;
DE   AltName: Full=Rab-like protein 4;
GN   Name=IFT27; Synonyms=RABL4, RAYL;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   IFT43_HUMAN             Reviewed;         208 AA.
AC   Q96FT9; B3KPT6; B4DZI9; G3V385; O95418; Q9ULA9;
DE   RecName: Full=Intraflagellar transport protein 43 homolog;
GN   Name=IFT43; Synonyms=C14orf179;
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0035721; P:intraciliary retrograde transport; IMP:UniProtKB.
//
ID   IFT46_HUMAN             Reviewed;         304 AA.
AC   Q9NQC8; A8K0F6; Q9H6V5;
DE   RecName: Full=Intraflagellar transport protein 46 homolog;
GN   Name=IFT46; Synonyms=C11orf2, C11orf60;
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:BHF-UCL.
DR   GO; GO:0042384; P:cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0042073; P:intraciliary transport; ISS:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; ISS:BHF-UCL.
//
ID   IFT52_HUMAN             Reviewed;         437 AA.
AC   Q9Y366; B3KMA1; E1P5W9; Q5H8Z0; Q9H1G3; Q9H1G4; Q9H1H2;
DE   RecName: Full=Intraflagellar transport protein 52 homolog;
DE   AltName: Full=Protein NGD5 homolog;
GN   Name=IFT52; Synonyms=C20orf9, NGD5; ORFNames=CGI-53;
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:BHF-UCL.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   IFT57_HUMAN             Reviewed;         429 AA.
AC   Q9NWB7; Q96DA9;
DE   RecName: Full=Intraflagellar transport protein 57 homolog;
DE   AltName: Full=Dermal papilla-derived protein 8;
DE   AltName: Full=Estrogen-related receptor beta-like protein 1;
DE   AltName: Full=HIP1-interacting protein;
DE   AltName: Full=MHS4R2;
GN   Name=IFT57; Synonyms=DERP8, ESRRBL1, HIPPI;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IFT74_HUMAN             Reviewed;         600 AA.
AC   Q96LB3; Q3B789; Q5VY34; Q6PGQ8; Q9H643; Q9H8G7;
DE   RecName: Full=Intraflagellar transport protein 74 homolog;
DE   AltName: Full=Capillary morphogenesis gene 1 protein;
DE            Short=CMG-1;
DE   AltName: Full=Coiled-coil domain-containing protein 2;
GN   Name=IFT74; Synonyms=CCDC2, CMG1;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0035735; P:intraciliary transport involved in cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   IFT80_HUMAN             Reviewed;         777 AA.
AC   Q9P2H3; B4E0K1; C9J8I0; Q3MJC4; Q86YF4; Q9UIX1;
DE   RecName: Full=Intraflagellar transport protein 80 homolog;
DE   AltName: Full=WD repeat-containing protein 56;
GN   Name=IFT80; Synonyms=KIAA1374, WDR56;
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:2000051; P:negative regulation of non-canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   IFT81_HUMAN             Reviewed;         676 AA.
AC   Q8WYA0; Q2YDY1; Q8NB51; Q9BSV2; Q9UNY8;
DE   RecName: Full=Intraflagellar transport protein 81 homolog;
DE   AltName: Full=Carnitine deficiency-associated protein expressed in ventricle 1;
DE            Short=CDV-1;
GN   Name=IFT81; Synonyms=CDV1;
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0035735; P:intraciliary transport involved in cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   IFT88_HUMAN             Reviewed;         833 AA.
AC   Q13099; A2A491; B4DUS2; Q5SZJ6; Q8N719;
DE   RecName: Full=Intraflagellar transport protein 88 homolog;
DE   AltName: Full=Recessive polycystic kidney disease protein Tg737 homolog;
DE   AltName: Full=Tetratricopeptide repeat protein 10;
DE            Short=TPR repeat protein 10;
GN   Name=IFT88; Synonyms=TG737, TTC10;
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060411; P:cardiac septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; IEA:Ensembl.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060426; P:lung vasculature development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:2000785; P:regulation of autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:1902017; P:regulation of cilium assembly; ISS:UniProtKB.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0021513; P:spinal cord dorsal/ventral patterning; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
//
ID   IF_HUMAN                Reviewed;         417 AA.
AC   P27352; B2RAN8; B4DVZ1;
DE   RecName: Full=Gastric intrinsic factor;
DE   AltName: Full=Intrinsic factor;
DE            Short=IF;
DE            Short=INF;
DE   Flags: Precursor;
GN   Name=GIF; Synonyms=IFMH;
DR   GO; GO:0031419; F:cobalamin binding; IDA:UniProtKB.
DR   GO; GO:0009235; P:cobalamin metabolic process; IBA:RefGenome.
DR   GO; GO:0015889; P:cobalamin transport; IMP:UniProtKB.
DR   GO; GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   IG2R_HUMAN              Reviewed;         113 AA.
AC   P09565; Q96F00;
DE   RecName: Full=Putative insulin-like growth factor 2-associated protein;
DE   AltName: Full=Cell growth-inhibiting gene 44 protein;
DE   AltName: Full=Insulin-like growth factor II-associated protein;
GN   ORFNames=GIG44, PP9974;
DR   GO; GO:0005520; F:insulin-like growth factor binding; NAS:UniProtKB.
//
ID   IG2AS_HUMAN             Reviewed;         168 AA.
AC   Q6U949; A5PKV8; A6NNQ2; Q7Z712; Q9P2W0;
DE   RecName: Full=Putative insulin-like growth factor 2 antisense gene protein;
DE   AltName: Full=IGF2 antisense RNA 1;
DE   AltName: Full=IGF2 antisense gene protein 1;
DE   AltName: Full=PEG8/IGF2AS protein;
DE   AltName: Full=Putative insulin-like growth factor 2 antisense gene protein 1;
DE            Short=IGF2-AS1;
GN   Name=IGF2-AS; Synonyms=IGF2-AS1, IGF2AS;
//
ID   IGBP1_HUMAN             Reviewed;         339 AA.
AC   P78318; Q8TAB2;
DE   RecName: Full=Immunoglobulin-binding protein 1;
DE   AltName: Full=B-cell signal transduction molecule alpha 4;
DE            Short=Protein alpha-4;
DE   AltName: Full=CD79a-binding protein 1;
DE   AltName: Full=Protein phosphatase 2/4/6 regulatory subunit;
DE   AltName: Full=Renal carcinoma antigen NY-REN-16;
GN   Name=IGBP1; Synonyms=IBP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; IDA:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0035308; P:negative regulation of protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0035306; P:positive regulation of dephosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060632; P:regulation of microtubule-based movement; IMP:UniProtKB.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:UniProtKB.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   IGDC3_HUMAN             Reviewed;         814 AA.
AC   Q8IVU1; O95215;
DE   RecName: Full=Immunoglobulin superfamily DCC subclass member 3;
DE   AltName: Full=Putative neuronal cell adhesion molecule;
DE   Flags: Precursor;
GN   Name=IGDCC3; Synonyms=PUNC;
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
//
ID   IGDC4_HUMAN             Reviewed;        1250 AA.
AC   Q8TDY8; Q9HCE4;
DE   RecName: Full=Immunoglobulin superfamily DCC subclass member 4;
DE   AltName: Full=Neighbor of punc e11;
DE   AltName: Full=Protein DDM36;
DE            Short=hDDM36;
DE   Flags: Precursor;
GN   Name=IGDCC4; Synonyms=DDM36, KIAA1628, NOPE;
//
ID   IGF1R_HUMAN             Reviewed;        1367 AA.
AC   P08069; B1B5Y2; Q14CV2; Q9UCC0;
DE   RecName: Full=Insulin-like growth factor 1 receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=Insulin-like growth factor I receptor;
DE            Short=IGF-I receptor;
DE   AltName: CD_antigen=CD221;
DE   Contains:
DE     RecName: Full=Insulin-like growth factor 1 receptor alpha chain;
DE   Contains:
DE     RecName: Full=Insulin-like growth factor 1 receptor beta chain;
DE   Flags: Precursor;
GN   Name=IGF1R;
DR   GuidetoPHARMACOLOGY; 1801; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0043559; F:insulin binding; IPI:BHF-UCL.
DR   GO; GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.
DR   GO; GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.
DR   GO; GO:0005520; F:insulin-like growth factor binding; IDA:UniProtKB.
DR   GO; GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.
DR   GO; GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IMP:BHF-UCL.
DR   GO; GO:0051389; P:inactivation of MAPKK activity; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010656; P:negative regulation of muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IC:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IGF1_HUMAN              Reviewed;         195 AA.
AC   P05019; B2RWM7; E9PD02; P01343; Q14620;
DE   RecName: Full=Insulin-like growth factor I;
DE            Short=IGF-I;
DE   AltName: Full=Mechano growth factor;
DE            Short=MGF;
DE   AltName: Full=Somatomedin-C;
DE   Flags: Precursor;
GN   Name=IGF1; Synonyms=IBP1;
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0005158; F:insulin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0035630; P:bone mineralization involved in bone maturation; IDA:BHF-UCL.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050650; P:chondroitin sulfate proteoglycan biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0009441; P:glycolate metabolic process; TAS:ProtInc.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
DR   GO; GO:0060426; P:lung vasculature development; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0014896; P:muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0045445; P:myoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0051450; P:myoblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0014904; P:myotube cell development; IDA:BHF-UCL.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.
DR   GO; GO:0034392; P:negative regulation of smooth muscle cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IDA:UniProtKB.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0021940; P:positive regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:UniProtKB.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IDA:BHF-UCL.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:2000288; P:positive regulation of myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR   GO; GO:0060736; P:prostate gland growth; IEA:Ensembl.
DR   GO; GO:0060741; P:prostate gland stromal morphogenesis; IEA:Ensembl.
DR   GO; GO:0030166; P:proteoglycan biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0032878; P:regulation of establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEP:BHF-UCL.
DR   GO; GO:0014834; P:satellite cell maintenance involved in skeletal muscle regeneration; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0060509; P:Type I pneumocyte differentiation; IEA:Ensembl.
DR   GO; GO:0060510; P:Type II pneumocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030104; P:water homeostasis; IEA:Ensembl.
//
ID   IGF2_HUMAN              Reviewed;         180 AA.
AC   P01344; B3KX48; B7WP08; C9JAF2; E3UN45; P78449; Q14299; Q1WM26;
AC   Q9UC68; Q9UC69;
DE   RecName: Full=Insulin-like growth factor II;
DE            Short=IGF-II;
DE   AltName: Full=Somatomedin-A;
DE   Contains:
DE     RecName: Full=Insulin-like growth factor II;
DE   Contains:
DE     RecName: Full=Insulin-like growth factor II Ala-25 Del;
DE   Contains:
DE     RecName: Full=Preptin;
DE   Flags: Precursor;
GN   Name=IGF2; ORFNames=PP1446;
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005158; F:insulin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; ISS:BHF-UCL.
DR   GO; GO:0030546; F:receptor activator activity; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0038028; P:insulin receptor signaling pathway via phosphatidylinositol 3-kinase; ISS:BHF-UCL.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; ISS:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IC:BHF-UCL.
DR   GO; GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
//
ID   IGFL1_HUMAN             Reviewed;         110 AA.
AC   Q6UW32;
DE   RecName: Full=Insulin growth factor-like family member 1;
DE   Flags: Precursor;
GN   Name=IGFL1; ORFNames=UNQ644/PRO1274;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   IGFL4_HUMAN             Reviewed;         124 AA.
AC   Q6B9Z1;
DE   RecName: Full=Insulin growth factor-like family member 4;
DE   Flags: Precursor;
GN   Name=IGFL4;
//
ID   IGFL2_HUMAN             Reviewed;         119 AA.
AC   Q6UWQ7; E9PAV1; Q6B9Z3;
DE   RecName: Full=Insulin growth factor-like family member 2;
DE   Flags: Precursor;
GN   Name=IGFL2; ORFNames=UNQ645/PRO1275;
//
ID   IGFN1_HUMAN             Reviewed;        1251 AA.
AC   Q86VF2; F8WAI1; Q9NT72;
DE   RecName: Full=Immunoglobulin-like and fibronectin type III domain-containing protein 1;
DE   AltName: Full=EEF1A2-binding protein 1;
DE   AltName: Full=KY-interacting protein 1;
GN   Name=IGFN1; Synonyms=EEF1A2BP1, KYIP1;
//
ID   IGFL3_HUMAN             Reviewed;         125 AA.
AC   Q6UXB1;
DE   RecName: Full=Insulin growth factor-like family member 3;
DE   Flags: Precursor;
GN   Name=IGFL3; ORFNames=UNQ483/PRO982;
//
ID   IGFR1_HUMAN             Reviewed;         355 AA.
AC   Q9H665; Q8N5X0;
DE   RecName: Full=IGF-like family receptor 1;
DE   AltName: Full=Transmembrane protein 149;
DE   AltName: Full=U2 small nuclear RNA auxiliary factor 1-like 4;
DE   Flags: Precursor;
GN   Name=IGFLR1; Synonyms=TMEM149, U2AF1L4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   IGHA1_HUMAN             Reviewed;         353 AA.
AC   P01876;
DE   RecName: Full=Ig alpha-1 chain C region;
GN   Name=IGHA1;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0003094; P:glomerular filtration; IMP:UniProt.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060267; P:positive regulation of respiratory burst; IDA:UniProt.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   IGHA2_HUMAN             Reviewed;         340 AA.
AC   P01877;
DE   RecName: Full=Ig alpha-2 chain C region;
GN   Name=IGHA2;
DR   GO; GO:0003823; F:antigen binding; TAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0003094; P:glomerular filtration; IMP:UniProt.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060267; P:positive regulation of respiratory burst; IDA:UniProt.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   IGHD_HUMAN              Reviewed;         384 AA.
AC   P01880; Q6P4I8; Q8WU38;
DE   RecName: Full=Ig delta chain C region;
GN   Name=IGHD;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   IGHE_HUMAN              Reviewed;         428 AA.
AC   P01854;
DE   RecName: Full=Ig epsilon chain C region;
GN   Name=IGHE;
DR   GuidetoPHARMACOLOGY; 2741; -.
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   IGHG1_HUMAN             Reviewed;         330 AA.
AC   P01857;
DE   RecName: Full=Ig gamma-1 chain C region;
GN   Name=IGHG1;
DR   GO; GO:0003823; F:antigen binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   IGHG2_HUMAN             Reviewed;         326 AA.
AC   P01859; A6NE66;
DE   RecName: Full=Ig gamma-2 chain C region;
GN   Name=IGHG2;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   IGHG3_HUMAN             Reviewed;         377 AA.
AC   P01860; A2NU35;
DE   RecName: Full=Ig gamma-3 chain C region;
DE   AltName: Full=HDC;
DE   AltName: Full=Heavy chain disease protein;
GN   Name=IGHG3;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   IGHG4_HUMAN             Reviewed;         327 AA.
AC   P01861;
DE   RecName: Full=Ig gamma-4 chain C region;
GN   Name=IGHG4;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   IGHM_HUMAN              Reviewed;         452 AA.
AC   P01871; P20769;
DE   RecName: Full=Ig mu chain C region;
GN   Name=IGHM;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IDA:UniProt.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IDA:UniProt.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
//
ID   IGIP_HUMAN              Reviewed;          53 AA.
AC   A6NJ69;
DE   RecName: Full=IgA-inducing protein homolog;
DE   Flags: Precursor;
GN   Name=IGIP; Synonyms=C5orf53;
//
ID   IGJ_HUMAN               Reviewed;         159 AA.
AC   P01591;
DE   RecName: Full=Immunoglobulin J chain;
DE   Flags: Precursor;
GN   Name=IGJ; Synonyms=IGCJ;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0019862; F:IgA binding; IMP:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0002250; P:adaptive immune response; IDA:UniProt.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0003094; P:glomerular filtration; IMP:UniProt.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IMP:UniProt.
DR   GO; GO:0060267; P:positive regulation of respiratory burst; IDA:UniProt.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   IGKC_HUMAN              Reviewed;         106 AA.
AC   P01834;
DE   RecName: Full=Ig kappa chain C region;
GN   Name=IGKC;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   IGLL1_HUMAN             Reviewed;         213 AA.
AC   P15814; Q0P681;
DE   RecName: Full=Immunoglobulin lambda-like polypeptide 1;
DE   AltName: Full=CD179 antigen-like family member B;
DE   AltName: Full=Ig lambda-5;
DE   AltName: Full=Immunoglobulin omega polypeptide;
DE   AltName: Full=Immunoglobulin-related protein 14.1;
DE   AltName: CD_antigen=CD179b;
DE   Flags: Precursor;
GN   Name=IGLL1; Synonyms=IGL1;
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   IGLL5_HUMAN             Reviewed;         214 AA.
AC   B9A064;
DE   RecName: Full=Immunoglobulin lambda-like polypeptide 5;
DE   AltName: Full=G lambda-1;
DE   AltName: Full=Germline immunoglobulin lambda 1;
DE   Flags: Precursor;
GN   Name=IGLL5;
//
ID   IGLO5_HUMAN             Reviewed;         336 AA.
AC   A6NGN9;
DE   RecName: Full=IgLON family member 5;
DE   Flags: Precursor;
GN   Name=IGLON5;
//
ID   IGS10_HUMAN             Reviewed;        2623 AA.
AC   Q6WRI0; Q86YJ9; Q8N772; Q8NA84;
DE   RecName: Full=Immunoglobulin superfamily member 10;
DE            Short=IgSF10;
DE   AltName: Full=Calvaria mechanical force protein 608;
DE            Short=CMF608;
DE   Flags: Precursor;
GN   Name=IGSF10; Synonyms=CMF608;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
//
ID   IGS11_HUMAN             Reviewed;         431 AA.
AC   Q5DX21; C9JZN0; Q8N4F1; Q8N7T8; Q8NDD2;
DE   RecName: Full=Immunoglobulin superfamily member 11;
DE            Short=IgSF11;
DE   AltName: Full=Brain and testis-specific immunoglobulin superfamily protein;
DE            Short=Bt-IGSF;
DE   AltName: Full=V-set and immunoglobulin domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=IGSF11; Synonyms=BTIGSF, CXADRL1, VSIG3;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   IGS21_HUMAN             Reviewed;         467 AA.
AC   Q96ID5; Q8NBR8;
DE   RecName: Full=Immunoglobulin superfamily member 21;
DE            Short=IgSF21;
DE   Flags: Precursor;
GN   Name=IGSF21;
//
ID   IGS22_HUMAN             Reviewed;         903 AA.
AC   Q8N9C0; A6NNA0; D6RGV7;
DE   RecName: Full=Immunoglobulin superfamily member 22;
DE            Short=IgSF22;
GN   Name=IGSF22;
//
ID   IGS23_HUMAN             Reviewed;         192 AA.
AC   A1L1A6;
DE   RecName: Full=Immunoglobulin superfamily member 23;
GN   Name=IGSF23;
//
ID   IGSF1_HUMAN             Reviewed;        1336 AA.
AC   Q8N6C5; B5MEG2; H9KV64; O15070; Q9NTC8;
DE   RecName: Full=Immunoglobulin superfamily member 1;
DE            Short=IgSF1;
DE   AltName: Full=Immunoglobulin-like domain-containing protein 1;
DE   AltName: Full=Inhibin-binding protein;
DE            Short=InhBP;
DE   AltName: Full=Pituitary gland-specific factor 2;
DE   AltName: Full=p120;
DE   Flags: Precursor;
GN   Name=IGSF1; Synonyms=IGDC1, KIAA0364, PGSF2;
DR   GO; GO:0015026; F:coreceptor activity; IEA:Ensembl.
DR   GO; GO:0034711; F:inhibin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   IGSF2_HUMAN             Reviewed;        1021 AA.
AC   Q93033; Q15856;
DE   RecName: Full=Immunoglobulin superfamily member 2;
DE            Short=IgSF2;
DE   AltName: Full=Cell surface glycoprotein V7;
DE   AltName: Full=Glu-Trp-Ile EWI motif-containing protein 101;
DE            Short=EWI-101;
DE   AltName: CD_antigen=CD101;
DE   Flags: Precursor;
GN   Name=CD101; Synonyms=EWI101, IGSF2, V7;
DR   GO; GO:0016812; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
//
ID   IGSF3_HUMAN             Reviewed;        1194 AA.
AC   O75054; A6NJZ6; A6NMC7;
DE   RecName: Full=Immunoglobulin superfamily member 3;
DE            Short=IgSF3;
DE   AltName: Full=Glu-Trp-Ile EWI motif-containing protein 3;
DE            Short=EWI-3;
DE   Flags: Precursor;
GN   Name=IGSF3; Synonyms=EWI3, KIAA0466;
DR   GO; GO:0032808; P:lacrimal gland development; IMP:UniProt.
//
ID   IGSF5_HUMAN             Reviewed;         407 AA.
AC   Q9NSI5;
DE   RecName: Full=Immunoglobulin superfamily member 5;
DE            Short=IgSF5;
DE   AltName: Full=Junctional adhesion molecule 4;
DE            Short=JAM-4;
GN   Name=IGSF5; Synonyms=JAM4;
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
//
ID   IGSF6_HUMAN             Reviewed;         241 AA.
AC   O95976; Q8WWD8;
DE   RecName: Full=Immunoglobulin superfamily member 6;
DE            Short=IgSF6;
DE   AltName: Full=Protein DORA;
DE   Flags: Precursor;
GN   Name=IGSF6; Synonyms=DORA;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   IGSF8_HUMAN             Reviewed;         613 AA.
AC   Q969P0; Q8NG09; Q96DP4; Q9BTG9;
DE   RecName: Full=Immunoglobulin superfamily member 8;
DE            Short=IgSF8;
DE   AltName: Full=CD81 partner 3;
DE   AltName: Full=Glu-Trp-Ile EWI motif-containing protein 2;
DE            Short=EWI-2;
DE   AltName: Full=Keratinocytes-associated transmembrane protein 4;
DE            Short=KCT-4;
DE   AltName: Full=LIR-D1;
DE   AltName: Full=Prostaglandin regulatory-like protein;
DE            Short=PGRL;
DE   AltName: CD_antigen=CD316;
DE   Flags: Precursor;
GN   Name=IGSF8; Synonyms=CD81P3, EWI2, KCT4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; NAS:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; NAS:UniProtKB.
//
ID   IHH_HUMAN               Reviewed;         411 AA.
AC   Q14623; B9EGM5; O43322; Q8N4B9;
DE   RecName: Full=Indian hedgehog protein;
DE            Short=IHH;
DE   AltName: Full=HHG-2;
DE   Contains:
DE     RecName: Full=Indian hedgehog protein N-product;
DE   Contains:
DE     RecName: Full=Indian hedgehog protein C-product;
DE   Flags: Precursor;
GN   Name=IHH;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005113; F:patched binding; IPI:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0060220; P:camera-type eye photoreceptor cell fate commitment; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:InterPro.
DR   GO; GO:0035988; P:chondrocyte proliferation; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0072498; P:embryonic skeletal joint development; IEA:Ensembl.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0060323; P:head morphogenesis; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0046639; P:negative regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048074; P:negative regulation of eye pigmentation; IEA:Ensembl.
DR   GO; GO:0033088; P:negative regulation of immature T cell proliferation in thymus; ISS:BHF-UCL.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0033085; P:negative regulation of T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IEA:Ensembl.
DR   GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0003406; P:retinal pigment epithelium development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0061053; P:somite development; ISS:BHF-UCL.
DR   GO; GO:0030704; P:vitelline membrane formation; IEA:Ensembl.
//
ID   IIGP5_HUMAN             Reviewed;         463 AA.
AC   Q6NXR0; Q05BR8;
DE   RecName: Full=Interferon-inducible GTPase 5;
DE            EC=3.6.5.-;
DE   AltName: Full=Immunity-related GTPase cinema 1;
GN   Name=IRGC; Synonyms=IIGP5, IRGC1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
//
ID   IKBA_HUMAN              Reviewed;         317 AA.
AC   P25963; B2R8L6;
DE   RecName: Full=NF-kappa-B inhibitor alpha;
DE   AltName: Full=I-kappa-B-alpha;
DE            Short=IkB-alpha;
DE            Short=IkappaBalpha;
DE   AltName: Full=Major histocompatibility complex enhancer-binding protein MAD3;
GN   Name=NFKBIA; Synonyms=IKBA, MAD3, NFKBI;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0070417; P:cellular response to cold; NAS:BHF-UCL.
DR   GO; GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:BHF-UCL.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043392; P:negative regulation of DNA binding; NAS:UniProtKB.
DR   GO; GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:MGI.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070427; P:nucleotide-binding oligomerization domain containing 1 signaling pathway; IEA:Ensembl.
DR   GO; GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IEA:Ensembl.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042345; P:regulation of NF-kappaB import into nucleus; NAS:UniProtKB.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IKBB_HUMAN              Reviewed;         356 AA.
AC   Q15653; A8K3F4; Q96BJ7;
DE   RecName: Full=NF-kappa-B inhibitor beta;
DE            Short=NF-kappa-BIB;
DE   AltName: Full=I-kappa-B-beta;
DE            Short=IkB-B;
DE            Short=IkB-beta;
DE            Short=IkappaBbeta;
DE   AltName: Full=Thyroid receptor-interacting protein 9;
DE            Short=TR-interacting protein 9;
DE            Short=TRIP-9;
GN   Name=NFKBIB; Synonyms=IKBB, TRIP9;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   IKBD_HUMAN              Reviewed;         313 AA.
AC   Q8NI38; Q8NI39; Q9BRG9;
DE   RecName: Full=NF-kappa-B inhibitor delta;
DE   AltName: Full=I-kappa-B-delta;
DE            Short=IkB-delta;
DE            Short=IkappaBdelta;
DE   AltName: Full=IkappaBNS;
DE   AltName: Full=T-cell activation NFKB-like protein;
DE   AltName: Full=TA-NFKBH;
GN   Name=NFKBID; Synonyms=IKBNS;
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0033085; P:negative regulation of T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0070245; P:positive regulation of thymocyte apoptotic process; IEA:Ensembl.
//
ID   IKBE_HUMAN              Reviewed;         500 AA.
AC   O00221; Q5T9V9;
DE   RecName: Full=NF-kappa-B inhibitor epsilon;
DE            Short=NF-kappa-BIE;
DE   AltName: Full=I-kappa-B-epsilon;
DE            Short=IkB-E;
DE            Short=IkB-epsilon;
DE            Short=IkappaBepsilon;
GN   Name=NFKBIE; Synonyms=IKBE;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.
DR   GO; GO:0042942; P:D-serine transport; IEA:Ensembl.
//
ID   IKBL1_HUMAN             Reviewed;         381 AA.
AC   Q9UBC1; A6NL91; B4DUW1; Q14625; Q5HYU4; Q5RJ72; Q5ST96; Q5STV4;
AC   Q5STV5; Q9UBX4;
DE   RecName: Full=NF-kappa-B inhibitor-like protein 1;
DE   AltName: Full=Inhibitor of kappa B-like protein;
DE            Short=I-kappa-B-like protein;
DE            Short=IkappaBL;
DE   AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1;
GN   Name=NFKBIL1; Synonyms=IKBL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.
//
ID   IKBP1_HUMAN             Reviewed;         260 AA.
AC   Q5VVH5;
DE   RecName: Full=Interleukin-1 receptor-associated kinase 1-binding protein 1;
DE            Short=IRAK1-binding protein 1;
GN   Name=IRAK1BP1;
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IKBZ_HUMAN              Reviewed;         718 AA.
AC   Q9BYH8; B3KNR2; D3DN54; Q8IUL4; Q8NAZ8;
DE   RecName: Full=NF-kappa-B inhibitor zeta;
DE   AltName: Full=I-kappa-B-zeta;
DE            Short=IkB-zeta;
DE            Short=IkappaBzeta;
DE   AltName: Full=IL-1 inducible nuclear ankyrin-repeat protein;
DE            Short=INAP;
DE   AltName: Full=Molecule possessing ankyrin repeats induced by lipopolysaccharide;
DE            Short=MAIL;
GN   Name=NFKBIZ; Synonyms=IKBZ, INAP, MAIL;
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IKIP_HUMAN              Reviewed;         350 AA.
AC   Q70UQ0; Q6ZWH4; Q70UP9; Q86V91; Q96ND2;
DE   RecName: Full=Inhibitor of nuclear factor kappa-B kinase-interacting protein;
DE            Short=I kappa-B kinase-interacting protein;
DE            Short=IKBKB-interacting protein;
DE            Short=IKK-interacting protein;
GN   Name=IKBIP; Synonyms=IKIP;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0010165; P:response to X-ray; TAS:BHF-UCL.
//
ID   IKKA_HUMAN              Reviewed;         745 AA.
AC   O15111; O14666; Q13132; Q5W0I4; Q92467;
DE   RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha;
DE            Short=I-kappa-B kinase alpha;
DE            Short=IKK-A;
DE            Short=IKK-alpha;
DE            Short=IkBKA;
DE            Short=IkappaB kinase;
DE            EC=2.7.11.10;
DE   AltName: Full=Conserved helix-loop-helix ubiquitous kinase;
DE   AltName: Full=I-kappa-B kinase 1;
DE            Short=IKK1;
DE   AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha;
DE            Short=NFKBIKA;
DE   AltName: Full=Transcription factor 16;
DE            Short=TCF-16;
GN   Name=CHUK; Synonyms=IKKA, TCF16;
DR   GuidetoPHARMACOLOGY; 1989; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008384; F:IkappaB kinase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0097110; F:scaffold protein binding; IDA:MGI.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0033194; P:response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0003009; P:skeletal muscle contraction; IEA:Ensembl.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   IKKB_HUMAN              Reviewed;         756 AA.
AC   O14920; B4DZ30; B4E0U4; O75327;
DE   RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit beta;
DE            Short=I-kappa-B-kinase beta;
DE            Short=IKK-B;
DE            Short=IKK-beta;
DE            Short=IkBKB;
DE            EC=2.7.11.10;
DE   AltName: Full=I-kappa-B kinase 2;
DE            Short=IKK2;
DE   AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase beta;
DE            Short=NFKBIKB;
GN   Name=IKBKB; Synonyms=IKKB;
DR   GuidetoPHARMACOLOGY; 2039; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008384; F:IkappaB kinase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0097110; F:scaffold protein binding; IDA:MGI.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; TAS:GOC.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:2001259; P:positive regulation of cation channel activity; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0042501; P:serine phosphorylation of STAT protein; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   IKKE_HUMAN              Reviewed;         716 AA.
AC   Q14164; D3DT78; Q3B754; Q3KR43; Q5JTS6;
DE   RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit epsilon;
DE            Short=I-kappa-B kinase epsilon;
DE            Short=IKK-E;
DE            Short=IKK-epsilon;
DE            Short=IkBKE;
DE            EC=2.7.11.10;
DE   AltName: Full=Inducible I kappa-B kinase;
DE            Short=IKK-i;
GN   Name=IKBKE; Synonyms=IKKE, IKKI, KIAA0151;
DR   GuidetoPHARMACOLOGY; 2040; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008384; F:IkappaB kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004704; F:NF-kappaB-inducing kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:UniProtKB.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0038061; P:NIK/NF-kappaB signaling; IDA:GOC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   IKZF1_HUMAN             Reviewed;         519 AA.
AC   Q13422; A4D260; B4E0Z1; D3DVM5; O00598; Q53XL2; Q69BM4; Q8WVA3;
DE   RecName: Full=DNA-binding protein Ikaros;
DE   AltName: Full=Ikaros family zinc finger protein 1;
DE   AltName: Full=Lymphoid transcription factor LyF-1;
GN   Name=IKZF1; Synonyms=IK1, IKAROS, LYF1, ZNFN1A1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0048732; P:gland development; IEA:Ensembl.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045660; P:positive regulation of neutrophil differentiation; IEA:Ensembl.
DR   GO; GO:0051138; P:positive regulation of NK T cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IKZF2_HUMAN             Reviewed;         526 AA.
AC   Q9UKS7; Q8N6S1;
DE   RecName: Full=Zinc finger protein Helios;
DE   AltName: Full=Ikaros family zinc finger protein 2;
GN   Name=IKZF2; Synonyms=HELIOS, ZNFN1A2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IKZF3_HUMAN             Reviewed;         509 AA.
AC   Q9UKT9; Q69BL6; Q69BL7; Q69BL8; Q69BL9; Q69BM0; Q69BM1; Q69BM2;
AC   Q69BM3; Q69BM5; Q8N574; Q8WWQ9; Q8WWR0; Q8WWR1; Q8WWR2; Q8WWR3;
DE   RecName: Full=Zinc finger protein Aiolos;
DE   AltName: Full=Ikaros family zinc finger protein 3;
GN   Name=IKZF3; Synonyms=ZNFN1A3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045577; P:regulation of B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030888; P:regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045619; P:regulation of lymphocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IKZF4_HUMAN             Reviewed;         585 AA.
AC   Q9H2S9; Q96JP3;
DE   RecName: Full=Zinc finger protein Eos;
DE   AltName: Full=Ikaros family zinc finger protein 4;
GN   Name=IKZF4; Synonyms=KIAA1782, ZNFN1A4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IKZF5_HUMAN             Reviewed;         419 AA.
AC   Q9H5V7; B3KVH7; D3DRE7; Q9H2T0;
DE   RecName: Full=Zinc finger protein Pegasus;
DE   AltName: Full=Ikaros family zinc finger protein 5;
GN   Name=IKZF5; Synonyms=ZNFN1A5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IL10_HUMAN              Reviewed;         178 AA.
AC   P22301;
DE   RecName: Full=Interleukin-10;
DE            Short=IL-10;
DE   AltName: Full=Cytokine synthesis inhibitory factor;
DE            Short=CSIF;
DE   Flags: Precursor;
GN   Name=IL10;
DR   GO; GO:0005125; F:cytokine activity; NAS:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0005141; F:interleukin-10 receptor binding; NAS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0042100; P:B cell proliferation; NAS:UniProtKB.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; NAS:BHF-UCL.
DR   GO; GO:0007253; P:cytoplasmic sequestering of NF-kappaB; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0030595; P:leukocyte chemotaxis; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IDA:MGI.
DR   GO; GO:0002875; P:negative regulation of chronic inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0002740; P:negative regulation of cytokine secretion involved in immune response; IDA:BHF-UCL.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0045355; P:negative regulation of interferon-alpha biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0045347; P:negative regulation of MHC class II biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0030886; P:negative regulation of myeloid dendritic cell activation; IEA:Ensembl.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; NAS:UniProtKB.
DR   GO; GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0002904; P:positive regulation of B cell apoptotic process; IDA:MGI.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:BHF-UCL.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0032800; P:receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:MGI.
DR   GO; GO:0045191; P:regulation of isotype switching; NAS:UniProtKB.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0034465; P:response to carbon monoxide; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IDA:BHF-UCL.
DR   GO; GO:0014854; P:response to inactivity; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IDA:UniProtKB.
DR   GO; GO:0042092; P:type 2 immune response; TAS:UniProtKB.
//
ID   IL11_HUMAN              Reviewed;         199 AA.
AC   P20809; B4DQV5; Q96EB4;
DE   RecName: Full=Interleukin-11;
DE            Short=IL-11;
DE   AltName: Full=Adipogenesis inhibitory factor;
DE            Short=AGIF;
DE   AltName: INN=Oprelvekin;
DE   Flags: Precursor;
GN   Name=IL11;
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0005142; F:interleukin-11 receptor binding; NAS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; NAS:UniProtKB.
DR   GO; GO:0030219; P:megakaryocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
//
ID   IL12A_HUMAN             Reviewed;         219 AA.
AC   P29459; Q96QZ1;
DE   RecName: Full=Interleukin-12 subunit alpha;
DE            Short=IL-12A;
DE   AltName: Full=Cytotoxic lymphocyte maturation factor 35 kDa subunit;
DE            Short=CLMF p35;
DE   AltName: Full=IL-12 subunit p35;
DE   AltName: Full=NK cell stimulatory factor chain 1;
DE            Short=NKSF1;
DE   Flags: Precursor;
GN   Name=IL12A; Synonyms=NKSF1;
DR   GO; GO:0005143; F:interleukin-12 receptor binding; NAS:UniProtKB.
DR   GO; GO:0045513; F:interleukin-27 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEP:UniProtKB.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0050671; P:positive regulation of lymphocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IDA:UniProtKB.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0002860; P:positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; IDA:UniProtKB.
DR   GO; GO:0051135; P:positive regulation of NK T cell activation; IDA:BHF-UCL.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0042520; P:positive regulation of tyrosine phosphorylation of Stat4 protein; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0010224; P:response to UV-B; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   IL12B_HUMAN             Reviewed;         328 AA.
AC   P29460;
DE   RecName: Full=Interleukin-12 subunit beta;
DE            Short=IL-12B;
DE   AltName: Full=Cytotoxic lymphocyte maturation factor 40 kDa subunit;
DE            Short=CLMF p40;
DE   AltName: Full=IL-12 subunit p40;
DE   AltName: Full=NK cell stimulatory factor chain 2;
DE            Short=NKSF2;
DE   Flags: Precursor;
GN   Name=IL12B; Synonyms=NKSF2;
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005143; F:interleukin-12 receptor binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IDA:BHF-UCL.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0042095; P:interferon-gamma biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0030101; P:natural killer cell activation; IDA:UniProtKB.
DR   GO; GO:0002323; P:natural killer cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IMP:BHF-UCL.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010535; P:positive regulation of activation of JAK2 kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:BHF-UCL.
DR   GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IDA:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:BHF-UCL.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0050671; P:positive regulation of lymphocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0043382; P:positive regulation of memory T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IDA:UniProtKB.
DR   GO; GO:0002860; P:positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; IDA:UniProtKB.
DR   GO; GO:0032819; P:positive regulation of natural killer cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; TAS:BHF-UCL.
DR   GO; GO:0051135; P:positive regulation of NK T cell activation; IDA:BHF-UCL.
DR   GO; GO:0051142; P:positive regulation of NK T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; ISS:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IDA:BHF-UCL.
DR   GO; GO:2000330; P:positive regulation of T-helper 17 cell lineage commitment; ISS:BHF-UCL.
DR   GO; GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:BHF-UCL.
DR   GO; GO:0034105; P:positive regulation of tissue remodeling; IC:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0042520; P:positive regulation of tyrosine phosphorylation of Stat4 protein; IDA:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042510; P:regulation of tyrosine phosphorylation of Stat1 protein; IDA:BHF-UCL.
DR   GO; GO:0010224; P:response to UV-B; IDA:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0019953; P:sexual reproduction; TAS:BHF-UCL.
DR   GO; GO:0042088; P:T-helper 1 type immune response; TAS:UniProtKB.
DR   GO; GO:0042093; P:T-helper cell differentiation; IDA:UniProtKB.
//
ID   IL13_HUMAN              Reviewed;         146 AA.
AC   P35225; O43644; Q4VB52; Q9UDC7;
DE   RecName: Full=Interleukin-13;
DE            Short=IL-13;
DE   Flags: Precursor;
GN   Name=IL13; Synonyms=NC30;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:1901247; P:negative regulation of lung ciliated cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0071635; P:negative regulation of transforming growth factor beta production; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0032723; P:positive regulation of connective tissue growth factor production; IEA:Ensembl.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IEA:Ensembl.
DR   GO; GO:1901251; P:positive regulation of lung goblet cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:2000231; P:positive regulation of pancreatic stellate cell proliferation; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0042526; P:positive regulation of tyrosine phosphorylation of Stat6 protein; IEA:Ensembl.
DR   GO; GO:0010155; P:regulation of proton transport; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   IL15_HUMAN              Reviewed;         162 AA.
AC   P40933; D3DNZ2; O00440; O43512; Q495Z8; Q6FGX7; Q93058; Q9UBA3;
DE   RecName: Full=Interleukin-15;
DE            Short=IL-15;
DE   Flags: Precursor;
GN   Name=IL15;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071305; P:cellular response to vitamin D; IEA:Ensembl.
DR   GO; GO:0045062; P:extrathymic T cell selection; IEA:Ensembl.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0001866; P:NK T cell proliferation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0050778; P:positive regulation of immune response; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0032819; P:positive regulation of natural killer cell proliferation; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0034105; P:positive regulation of tissue remodeling; IC:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
DR   GO; GO:0050691; P:regulation of defense response to virus by host; IEA:Ensembl.
DR   GO; GO:0045580; P:regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0014732; P:skeletal muscle atrophy; IEA:Ensembl.
//
ID   IL16_HUMAN              Reviewed;        1332 AA.
AC   Q14005; A6NM20; A8MU65; B9EGR6; Q16435; Q6VVE6; Q6ZMQ7; Q9UP18;
DE   RecName: Full=Pro-interleukin-16;
DE   Contains:
DE     RecName: Full=Interleukin-16;
DE              Short=IL-16;
DE     AltName: Full=Lymphocyte chemoattractant factor;
DE              Short=LCF;
GN   Name=IL16;
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0030595; P:leukocyte chemotaxis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IL17B_HUMAN             Reviewed;         180 AA.
AC   Q9UHF5; Q14CE5;
DE   RecName: Full=Interleukin-17B;
DE            Short=IL-17B;
DE   AltName: Full=Cytokine Zcyto7;
DE   AltName: Full=Interleukin-20;
DE            Short=IL-20;
DE   AltName: Full=Neuronal interleukin-17-related factor;
DE   Flags: Precursor;
GN   Name=IL17B; Synonyms=IL20, NIRF, ZCYTO7; ORFNames=UNQ516/PRO1031;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
//
ID   IL17C_HUMAN             Reviewed;         197 AA.
AC   Q9P0M4; Q3MIG8; Q9HC75;
DE   RecName: Full=Interleukin-17C;
DE            Short=IL-17C;
DE   AltName: Full=Cytokine CX2;
DE   Flags: Precursor;
GN   Name=IL17C; ORFNames=UNQ561/PRO1122;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030223; P:neutrophil differentiation; IEA:Ensembl.
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
//
ID   IL17D_HUMAN             Reviewed;         202 AA.
AC   Q8TAD2; B1AM69;
DE   RecName: Full=Interleukin-17D;
DE            Short=IL-17D;
DE   AltName: Full=Interleukin-27;
DE            Short=IL-27;
DE   Flags: Precursor;
GN   Name=IL17D; Synonyms=IL27; ORFNames=UNQ3096/PRO21175;
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
//
ID   IL17F_HUMAN             Reviewed;         163 AA.
AC   Q96PD4; Q6NSI0; Q7Z6P4; Q96PI8; Q9NUE6;
DE   RecName: Full=Interleukin-17F;
DE            Short=IL-17F;
DE   AltName: Full=Cytokine ML-1;
DE   Flags: Precursor;
GN   Name=IL17F;
DR   GO; GO:0005125; F:cytokine activity; IDA:UniProtKB.
DR   GO; GO:0019955; F:cytokine binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; IDA:UniProtKB.
DR   GO; GO:0042089; P:cytokine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0042109; P:lymphotoxin A biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IDA:UniProtKB.
DR   GO; GO:0045423; P:regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045076; P:regulation of interleukin-2 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045408; P:regulation of interleukin-6 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045414; P:regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
//
ID   IL17_HUMAN              Reviewed;         155 AA.
AC   Q16552; Q5T2P0;
DE   RecName: Full=Interleukin-17A;
DE            Short=IL-17;
DE            Short=IL-17A;
DE   AltName: Full=Cytotoxic T-lymphocyte-associated antigen 8;
DE            Short=CTLA-8;
DE   Flags: Precursor;
GN   Name=IL17A; Synonyms=CTLA8, IL17;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0072537; P:fibroblast activation; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:1900017; P:positive regulation of cytokine production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0032747; P:positive regulation of interleukin-23 production; IDA:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   IL18R_HUMAN             Reviewed;         541 AA.
AC   Q13478; B2R9Y5; Q52LC9;
DE   RecName: Full=Interleukin-18 receptor 1;
DE            Short=IL-18R-1;
DE            Short=IL-18R1;
DE   AltName: Full=CD218 antigen-like family member A;
DE   AltName: Full=CDw218a;
DE   AltName: Full=IL1 receptor-related protein;
DE            Short=IL-1Rrp;
DE            Short=IL1R-rp;
DE   AltName: CD_antigen=CD218a;
DE   Flags: Precursor;
GN   Name=IL18R1; Synonyms=IL1RRP;
DR   GO; GO:0004908; F:interleukin-1 receptor activity; IEA:InterPro.
DR   GO; GO:0042008; F:interleukin-18 receptor activity; IEA:Ensembl.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0030101; P:natural killer cell activation; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0045063; P:T-helper 1 cell differentiation; IEA:Ensembl.
//
ID   IL18_HUMAN              Reviewed;         193 AA.
AC   Q14116; O75599; Q6FGY3; Q6WWJ7;
DE   RecName: Full=Interleukin-18;
DE            Short=IL-18;
DE   AltName: Full=Iboctadekin;
DE   AltName: Full=Interferon gamma-inducing factor;
DE            Short=IFN-gamma-inducing factor;
DE   AltName: Full=Interleukin-1 gamma;
DE            Short=IL-1 gamma;
DE   Flags: Precursor;
GN   Name=IL18; Synonyms=IGIF, IL1F4;
DR   GO; GO:0005125; F:cytokine activity; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0042033; P:chemokine biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042253; P:granulocyte macrophage colony-stimulating factor biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0042095; P:interferon-gamma biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042231; P:interleukin-13 biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042094; P:interleukin-2 biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0030101; P:natural killer cell activation; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0032819; P:positive regulation of natural killer cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0051142; P:positive regulation of NK T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0034105; P:positive regulation of tissue remodeling; IC:BHF-UCL.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0030431; P:sleep; ISS:UniProtKB.
DR   GO; GO:0042088; P:T-helper 1 type immune response; IDA:UniProtKB.
DR   GO; GO:0042092; P:type 2 immune response; TAS:UniProtKB.
//
ID   IL1AP_HUMAN             Reviewed;         570 AA.
AC   Q9NPH3; B1NLD0; D3DNW0; O14915; Q86WJ7;
DE   RecName: Full=Interleukin-1 receptor accessory protein;
DE            Short=IL-1 receptor accessory protein;
DE            Short=IL-1RAcP;
DE   AltName: Full=Interleukin-1 receptor 3;
DE            Short=IL-1R-3;
DE            Short=IL-1R3;
DE   Flags: Precursor;
GN   Name=IL1RAP; Synonyms=C3orf13, IL1R3;
DR   GO; GO:0004908; F:interleukin-1 receptor activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0042094; P:interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   IL19_HUMAN              Reviewed;         177 AA.
AC   Q9UHD0; Q5VUT3; Q96QR4; Q9NUA0;
DE   RecName: Full=Interleukin-19;
DE            Short=IL-19;
DE   AltName: Full=Melanoma differentiation-associated protein-like protein;
DE   AltName: Full=NG.1;
DE   Flags: Precursor;
GN   Name=IL19; Synonyms=ZMDA1;
DR   GO; GO:0005125; F:cytokine activity; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0042226; P:interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   IL1A_HUMAN              Reviewed;         271 AA.
AC   P01583; Q53QF9; Q7RU02;
DE   RecName: Full=Interleukin-1 alpha;
DE            Short=IL-1 alpha;
DE   AltName: Full=Hematopoietin-1;
DE   Flags: Precursor;
GN   Name=IL1A; Synonyms=IL1F1;
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0005125; F:cytokine activity; IMP:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0001660; P:fever generation; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:BHF-UCL.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:BHF-UCL.
DR   GO; GO:0046688; P:response to copper ion; IDA:UniProtKB.
//
ID   IL1B_HUMAN              Reviewed;         269 AA.
AC   P01584; Q53X59; Q53XX2; Q7M4S7; Q7RU01; Q96HE5; Q9UCT6;
DE   RecName: Full=Interleukin-1 beta;
DE            Short=IL-1 beta;
DE   AltName: Full=Catabolin;
DE   Flags: Precursor;
GN   Name=IL1B; Synonyms=IL1F2;
DR   GuidetoPHARMACOLOGY; 2623; -.
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0005149; F:interleukin-1 receptor binding; NAS:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0035690; P:cellular response to drug; IDA:MGI.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0071310; P:cellular response to organic substance; IDA:MGI.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; TAS:BHF-UCL.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0001660; P:fever generation; IEA:UniProtKB-KW.
DR   GO; GO:0030213; P:hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0032611; P:interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0070487; P:monocyte aggregation; IDA:UniProtKB.
DR   GO; GO:0070164; P:negative regulation of adiponectin secretion; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:BHF-UCL.
DR   GO; GO:0010829; P:negative regulation of glucose transport; ISS:BHF-UCL.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0045833; P:negative regulation of lipid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; ISS:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060559; P:positive regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0060355; P:positive regulation of cell adhesion molecule production; NAS:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0031622; P:positive regulation of fever generation; ISS:BHF-UCL.
DR   GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IDA:BHF-UCL.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; NAS:BHF-UCL.
DR   GO; GO:0033129; P:positive regulation of histone phosphorylation; NAS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; TAS:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0050996; P:positive regulation of lipid catabolic process; ISS:BHF-UCL.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IMP:BHF-UCL.
DR   GO; GO:0071639; P:positive regulation of monocyte chemotactic protein-1 production; IDA:UniProtKB.
DR   GO; GO:0035505; P:positive regulation of myosin light chain kinase activity; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032308; P:positive regulation of prostaglandin secretion; ISS:BHF-UCL.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; NAS:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0002711; P:positive regulation of T cell mediated immunity; IC:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IDA:BHF-UCL.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0030730; P:sequestering of triglyceride; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0014805; P:smooth muscle adaptation; NAS:BHF-UCL.
//
ID   IL1FA_HUMAN             Reviewed;         152 AA.
AC   Q8WWZ1; Q53SR9; Q56AT8; Q7RTZ5; Q969H5; Q9BYX1;
DE   RecName: Full=Interleukin-1 family member 10;
DE            Short=IL-1F10;
DE   AltName: Full=Family of interleukin 1-theta;
DE            Short=FIL1 theta;
DE   AltName: Full=Interleukin-1 HY2;
DE            Short=IL-1HY2;
DE   AltName: Full=Interleukin-1 theta;
DE            Short=IL-1 theta;
DE   AltName: Full=Interleukin-38;
DE            Short=IL-38;
GN   Name=IL1F10; Synonyms=FIL1T, IL1HY2, IL38;
GN   ORFNames=FKSG75, UNQ6119/PRO20041;
//
ID   IL1R1_HUMAN             Reviewed;         569 AA.
AC   P14778; Q587I7;
DE   RecName: Full=Interleukin-1 receptor type 1;
DE            Short=IL-1R-1;
DE            Short=IL-1RT-1;
DE            Short=IL-1RT1;
DE   AltName: Full=CD121 antigen-like family member A;
DE   AltName: Full=Interleukin-1 receptor alpha;
DE            Short=IL-1R-alpha;
DE   AltName: Full=Interleukin-1 receptor type I;
DE   AltName: Full=p80;
DE   AltName: CD_antigen=CD121a;
DE   Contains:
DE     RecName: Full=Interleukin-1 receptor type 1, membrane form;
DE              Short=mIL-1R1;
DE              Short=mIL-1RI;
DE   Contains:
DE     RecName: Full=Interleukin-1 receptor type 1, soluble form;
DE              Short=sIL-1R1;
DE              Short=sIL-1RI;
DE   Flags: Precursor;
GN   Name=IL1R1; Synonyms=IL1R, IL1RA, IL1RT1;
DR   GO; GO:0004908; F:interleukin-1 receptor activity; IDA:BHF-UCL.
DR   GO; GO:0004909; F:interleukin-1, Type I, activating receptor activity; TAS:ProtInc.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IDA:BHF-UCL.
//
ID   IL1R2_HUMAN             Reviewed;         398 AA.
AC   P27930; D3DVJ5; Q6LCE6; Q9UE68;
DE   RecName: Full=Interleukin-1 receptor type 2;
DE            Short=IL-1R-2;
DE            Short=IL-1RT-2;
DE            Short=IL-1RT2;
DE   AltName: Full=CD121 antigen-like family member B;
DE   AltName: Full=CDw121b;
DE   AltName: Full=IL-1 type II receptor;
DE   AltName: Full=Interleukin-1 receptor beta;
DE            Short=IL-1R-beta;
DE   AltName: Full=Interleukin-1 receptor type II;
DE   AltName: CD_antigen=CD121b;
DE   Contains:
DE     RecName: Full=Interleukin-1 receptor type 2, membrane form;
DE              Short=mIL-1R2;
DE              Short=mIL-1RII;
DE   Contains:
DE     RecName: Full=Interleukin-1 receptor type 2, soluble form;
DE              Short=sIL-1R2;
DE              Short=sIL-1RII;
DE   Flags: Precursor;
GN   Name=IL1R2; Synonyms=IL1RB;
DR   GO; GO:0004908; F:interleukin-1 receptor activity; TAS:ProtInc.
DR   GO; GO:0004910; F:interleukin-1, Type II, blocking receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   IL20_HUMAN              Reviewed;         176 AA.
AC   Q9NYY1; Q17RB3; Q2THG6; Q96QZ6;
DE   RecName: Full=Interleukin-20;
DE            Short=IL-20;
DE   AltName: Full=Cytokine Zcyto10;
DE   Flags: Precursor;
GN   Name=IL20; Synonyms=ZCYTO10; ORFNames=UNQ852/PRO1801;
DR   GO; GO:0045517; F:interleukin-20 receptor binding; TAS:UniProtKB.
DR   GO; GO:0045606; P:positive regulation of epidermal cell differentiation; TAS:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; TAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.
//
ID   IL1RA_HUMAN             Reviewed;         177 AA.
AC   P18510; A8K4G1; Q14628; Q53SC2; Q7RTZ4; Q96GD6; Q9UPC0;
DE   RecName: Full=Interleukin-1 receptor antagonist protein;
DE            Short=IL-1RN;
DE            Short=IL-1ra;
DE            Short=IRAP;
DE   AltName: Full=ICIL-1RA;
DE   AltName: Full=IL1 inhibitor;
DE   AltName: INN=Anakinra;
DE   Flags: Precursor;
GN   Name=IL1RN; Synonyms=IL1F3, IL1RA;
DR   GO; GO:0005152; F:interleukin-1 receptor antagonist activity; IDA:BHF-UCL.
DR   GO; GO:0005149; F:interleukin-1 receptor binding; IDA:BHF-UCL.
DR   GO; GO:0045352; F:interleukin-1 Type I receptor antagonist activity; IDA:BHF-UCL.
DR   GO; GO:0045353; F:interleukin-1 Type II receptor antagonist activity; IDA:BHF-UCL.
DR   GO; GO:0005150; F:interleukin-1, Type I receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005151; F:interleukin-1, Type II receptor binding; IPI:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IDA:BHF-UCL.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0002439; P:chronic inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0001660; P:fever generation; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:2000660; P:negative regulation of interleukin-1-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045837; P:negative regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IDA:BHF-UCL.
DR   GO; GO:0070670; P:response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
//
ID   IL21R_HUMAN             Reviewed;         538 AA.
AC   Q9HBE5; A8K9E8; D3DWF7; Q96HZ1; Q9HB91;
DE   RecName: Full=Interleukin-21 receptor;
DE            Short=IL-21 receptor;
DE            Short=IL-21R;
DE   AltName: Full=Novel interleukin receptor;
DE   AltName: CD_antigen=CD360;
DE   Flags: Precursor;
GN   Name=IL21R; Synonyms=NILR; ORFNames=UNQ3121/PRO10273;
DR   GO; GO:0001532; F:interleukin-21 receptor activity; NAS:UniProtKB.
DR   GO; GO:0038114; P:interleukin-21-mediated signaling pathway; NAS:GOC.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
//
ID   IL21_HUMAN              Reviewed;         155 AA.
AC   Q9HBE4; A5J0L4;
DE   RecName: Full=Interleukin-21;
DE            Short=IL-21;
DE   AltName: Full=Za11;
DE   Flags: Precursor;
GN   Name=IL21;
DR   GO; GO:0005126; F:cytokine receptor binding; TAS:UniProtKB.
DR   GO; GO:0005134; F:interleukin-2 receptor binding; IPI:UniProtKB.
DR   GO; GO:0048469; P:cell maturation; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0002729; P:positive regulation of natural killer cell cytokine production; IEA:Ensembl.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0034105; P:positive regulation of tissue remodeling; IC:BHF-UCL.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IDA:MGI.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   IL22_HUMAN              Reviewed;         179 AA.
AC   Q9GZX6;
DE   RecName: Full=Interleukin-22;
DE            Short=IL-22;
DE   AltName: Full=Cytokine Zcyto18;
DE   AltName: Full=IL-10-related T-cell-derived-inducible factor;
DE            Short=IL-TIF;
DE   Flags: Precursor;
GN   Name=IL22; Synonyms=ILTIF, ZCYTO18; ORFNames=UNQ3099/PRO10096;
DR   GO; GO:0045518; F:interleukin-22 receptor binding; NAS:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
//
ID   IL23A_HUMAN             Reviewed;         189 AA.
AC   Q9NPF7; Q6NZ80; Q6NZ82; Q9H2A5;
DE   RecName: Full=Interleukin-23 subunit alpha;
DE            Short=IL-23 subunit alpha;
DE            Short=IL-23-A;
DE   AltName: Full=Interleukin-23 subunit p19;
DE            Short=IL-23p19;
DE   Flags: Precursor;
GN   Name=IL23A; Synonyms=SGRF; ORFNames=UNQ2498/PRO5798;
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IDA:BHF-UCL.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IMP:BHF-UCL.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010535; P:positive regulation of activation of JAK2 kinase activity; IDA:BHF-UCL.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:BHF-UCL.
DR   GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IDA:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:BHF-UCL.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0043382; P:positive regulation of memory T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IC:BHF-UCL.
DR   GO; GO:0032819; P:positive regulation of natural killer cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; TAS:BHF-UCL.
DR   GO; GO:0051135; P:positive regulation of NK T cell activation; IDA:BHF-UCL.
DR   GO; GO:0051142; P:positive regulation of NK T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; ISS:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IDA:BHF-UCL.
DR   GO; GO:2000330; P:positive regulation of T-helper 17 cell lineage commitment; ISS:BHF-UCL.
DR   GO; GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:BHF-UCL.
DR   GO; GO:0034105; P:positive regulation of tissue remodeling; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0042520; P:positive regulation of tyrosine phosphorylation of Stat4 protein; IDA:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
DR   GO; GO:0042510; P:regulation of tyrosine phosphorylation of Stat1 protein; IDA:BHF-UCL.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0048771; P:tissue remodeling; IEA:UniProtKB-KW.
//
ID   IL24_HUMAN              Reviewed;         206 AA.
AC   Q13007; Q2YHE5; Q53XZ7; Q5YLN8; Q96DB0; Q96KG4;
DE   RecName: Full=Interleukin-24;
DE            Short=IL-24;
DE   AltName: Full=Melanoma differentiation-associated gene 7 protein;
DE            Short=MDA-7;
DE   AltName: Full=Suppression of tumorigenicity 16 protein;
DE   Flags: Precursor;
GN   Name=IL24; Synonyms=MDA7, ST16;
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
DR   GO; GO:0033136; P:serine phosphorylation of STAT3 protein; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   IL23R_HUMAN             Reviewed;         629 AA.
AC   Q5VWK5; C9JGX4; Q4VGP1; Q4VGP2; Q4VGP3; Q4VGP4; Q4VGP5; Q4VGP6;
AC   Q5VWK7; Q8IW84; Q8NFQ9; Q96AS1;
DE   RecName: Full=Interleukin-23 receptor;
DE            Short=IL-23 receptor;
DE            Short=IL-23R;
DE   Flags: Precursor;
GN   Name=IL23R;
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0038155; P:interleukin-23-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IMP:BHF-UCL.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IC:BHF-UCL.
DR   GO; GO:0010535; P:positive regulation of activation of JAK2 kinase activity; IC:BHF-UCL.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:BHF-UCL.
DR   GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; IC:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IDA:BHF-UCL.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IC:BHF-UCL.
DR   GO; GO:0043382; P:positive regulation of memory T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0032819; P:positive regulation of natural killer cell proliferation; IC:BHF-UCL.
DR   GO; GO:0051135; P:positive regulation of NK T cell activation; IC:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IC:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; ISS:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IC:BHF-UCL.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IDA:BHF-UCL.
DR   GO; GO:2000330; P:positive regulation of T-helper 17 cell lineage commitment; ISS:BHF-UCL.
DR   GO; GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IC:BHF-UCL.
DR   GO; GO:0042520; P:positive regulation of tyrosine phosphorylation of Stat4 protein; IC:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IC:BHF-UCL.
DR   GO; GO:0042510; P:regulation of tyrosine phosphorylation of Stat1 protein; IC:BHF-UCL.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.
//
ID   IL25_HUMAN              Reviewed;         177 AA.
AC   Q9H293; Q2M3F0; Q8IZV3; Q8WXB0;
DE   RecName: Full=Interleukin-25;
DE            Short=IL-25;
DE   AltName: Full=Interleukin-17E;
DE            Short=IL-17E;
DE   Flags: Precursor;
GN   Name=IL25; Synonyms=IL17E; ORFNames=UNQ3120/PRO10272;
DR   GO; GO:0030380; F:interleukin-17E receptor binding; TAS:UniProtKB.
DR   GO; GO:0030222; P:eosinophil differentiation; IEA:Ensembl.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009620; P:response to fungus; IEA:Ensembl.
DR   GO; GO:0009624; P:response to nematode; IEA:Ensembl.
//
ID   IL27A_HUMAN             Reviewed;         243 AA.
AC   Q8NEV9; A0N0L2; Q6P676;
DE   RecName: Full=Interleukin-27 subunit alpha;
DE            Short=IL-27 subunit alpha;
DE            Short=IL-27-A;
DE            Short=IL27-A;
DE   AltName: Full=Interleukin-30;
DE   AltName: Full=p28;
DE   Flags: Precursor;
GN   Name=IL27; Synonyms=IL27A, IL30;
DR   GO; GO:0045523; F:interleukin-27 receptor binding; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0042129; P:regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045625; P:regulation of T-helper 1 cell differentiation; IDA:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
//
ID   IL26_HUMAN              Reviewed;         171 AA.
AC   Q9NPH9;
DE   RecName: Full=Interleukin-26;
DE            Short=IL-26;
DE   AltName: Full=Protein AK155;
DE   Flags: Precursor;
GN   Name=IL26; Synonyms=AK155;
DR   GO; GO:0005125; F:cytokine activity; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   IL27B_HUMAN             Reviewed;         229 AA.
AC   Q14213; A0N0N2; O75269;
DE   RecName: Full=Interleukin-27 subunit beta;
DE            Short=IL-27 subunit beta;
DE            Short=IL-27B;
DE   AltName: Full=Epstein-Barr virus-induced gene 3 protein;
DE            Short=EBV-induced gene 3 protein;
DE   Flags: Precursor;
GN   Name=EBI3; Synonyms=IL27B;
DR   GO; GO:0004896; F:cytokine receptor activity; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IPI:GOC.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; TAS:UniProtKB.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042088; P:T-helper 1 type immune response; TAS:UniProtKB.
//
ID   IL2RA_HUMAN             Reviewed;         272 AA.
AC   P01589; Q5W007;
DE   RecName: Full=Interleukin-2 receptor subunit alpha;
DE            Short=IL-2 receptor subunit alpha;
DE            Short=IL-2-RA;
DE            Short=IL-2R subunit alpha;
DE            Short=IL2-RA;
DE   AltName: Full=TAC antigen;
DE   AltName: Full=p55;
DE   AltName: CD_antigen=CD25;
DE   Flags: Precursor;
GN   Name=IL2RA;
DR   GuidetoPHARMACOLOGY; 1695; -.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004911; F:interleukin-2 receptor activity; TAS:ProtInc.
DR   GO; GO:0006924; P:activation-induced cell death of T cells; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IEA:Ensembl.
DR   GO; GO:0050777; P:negative regulation of immune response; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0046013; P:regulation of T cell homeostatic proliferation; IEA:Ensembl.
//
ID   IL2RB_HUMAN             Reviewed;         551 AA.
AC   P14784; B2R765;
DE   RecName: Full=Interleukin-2 receptor subunit beta;
DE            Short=IL-2 receptor subunit beta;
DE            Short=IL-2R subunit beta;
DE            Short=IL-2RB;
DE   AltName: Full=High affinity IL-2 receptor subunit beta;
DE   AltName: Full=p70-75;
DE            Short=p75;
DE   AltName: CD_antigen=CD122;
DE   Flags: Precursor;
GN   Name=IL2RB;
DR   GO; GO:0019976; F:interleukin-2 binding; ISS:UniProtKB.
DR   GO; GO:0004911; F:interleukin-2 receptor activity; IDA:MGI.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:MGI.
DR   GO; GO:0038110; P:interleukin-2-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IL2RG_HUMAN             Reviewed;         369 AA.
AC   P31785; Q5FC12;
DE   RecName: Full=Cytokine receptor common subunit gamma;
DE   AltName: Full=Interleukin-2 receptor subunit gamma;
DE            Short=IL-2 receptor subunit gamma;
DE            Short=IL-2R subunit gamma;
DE            Short=IL-2RG;
DE   AltName: Full=gammaC;
DE   AltName: Full=p64;
DE   AltName: CD_antigen=CD132;
DE   Flags: Precursor;
GN   Name=IL2RG;
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0019976; F:interleukin-2 binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0038110; P:interleukin-2-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0035771; P:interleukin-4-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0038111; P:interleukin-7-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IL2_HUMAN               Reviewed;         153 AA.
AC   P60568; P01585;
DE   RecName: Full=Interleukin-2;
DE            Short=IL-2;
DE   AltName: Full=T-cell growth factor;
DE            Short=TCGF;
DE   AltName: INN=Aldesleukin;
DE   Flags: Precursor;
GN   Name=IL2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0005125; F:cytokine activity; IDA:MGI.
DR   GO; GO:0043208; F:glycosphingolipid binding; IEA:Ensembl.
DR   GO; GO:0008083; F:growth factor activity; TAS:UniProtKB.
DR   GO; GO:0005134; F:interleukin-2 receptor binding; TAS:UniProtKB.
DR   GO; GO:0019209; F:kinase activator activity; TAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0030101; P:natural killer cell activation; TAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0002903; P:negative regulation of B cell apoptotic process; IDA:MGI.
DR   GO; GO:0045822; P:negative regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0050672; P:negative regulation of lymphocyte proliferation; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:MGI.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IDA:MGI.
DR   GO; GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; IEA:Ensembl.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl.
DR   GO; GO:0045591; P:positive regulation of regulatory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0034105; P:positive regulation of tissue remodeling; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0046013; P:regulation of T cell homeostatic proliferation; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; TAS:UniProtKB.
//
ID   IL31R_HUMAN             Reviewed;         732 AA.
AC   Q8NI17; A6NIF8; Q2TBA1; Q6EBC3; Q6EBC4; Q6EBC5; Q6EBC6; Q6UWL8;
AC   Q8WYJ0;
DE   RecName: Full=Interleukin-31 receptor subunit alpha;
DE            Short=IL-31 receptor subunit alpha;
DE            Short=IL-31R subunit alpha;
DE            Short=IL-31R-alpha;
DE            Short=IL-31RA;
DE   AltName: Full=Cytokine receptor-like 3;
DE   AltName: Full=GLM-R;
DE            Short=hGLM-R;
DE   AltName: Full=Gp130-like monocyte receptor;
DE            Short=Gp130-like receptor;
DE   AltName: Full=ZcytoR17;
DE   Flags: Precursor;
GN   Name=IL31RA; Synonyms=CRL3, GPL; ORFNames=UNQ6368/PRO21073/PRO21384;
DR   GO; GO:0019955; F:cytokine binding; NAS:UniProtKB.
DR   GO; GO:0004896; F:cytokine receptor activity; TAS:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006952; P:defense response; NAS:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0007259; P:JAK-STAT cascade; IEP:UniProtKB.
DR   GO; GO:0030225; P:macrophage differentiation; NAS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; NAS:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0043031; P:negative regulation of macrophage activation; NAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IEP:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IEP:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
//
ID   IL31_HUMAN              Reviewed;         164 AA.
AC   Q6EBC2; A2RUQ1;
DE   RecName: Full=Interleukin-31;
DE            Short=IL-31;
DE   Flags: Precursor;
GN   Name=IL31;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   IL32_HUMAN              Reviewed;         234 AA.
AC   P24001; A6NNM0; A8MPX0; B4DJM1; B8Q191; D3DUB0; D3DUB2; Q5VFH7;
AC   Q5VFH8; Q8WV38; Q96GK9;
DE   RecName: Full=Interleukin-32;
DE            Short=IL-32;
DE   AltName: Full=Natural killer cells protein 4;
DE   AltName: Full=Tumor necrosis factor alpha-inducing factor;
DE   Flags: Precursor;
GN   Name=IL32; Synonyms=NK4, TAIF;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   IL33_HUMAN              Reviewed;         270 AA.
AC   O95760; B2R8L1; B4DJ35; B4E1Q9; D3DRI5; E7EAX4; Q2YEJ5;
DE   RecName: Full=Interleukin-33;
DE            Short=IL-33;
DE   AltName: Full=Interleukin-1 family member 11;
DE            Short=IL-1F11;
DE   AltName: Full=Nuclear factor from high endothelial venules;
DE            Short=NF-HEV;
DE   Flags: Precursor;
GN   Name=IL33; Synonyms=C9orf26, IL1F11, NFHEV;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051025; P:negative regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0002686; P:negative regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0002826; P:negative regulation of T-helper 1 type immune response; IEA:Ensembl.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IDA:BHF-UCL.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0032736; P:positive regulation of interleukin-13 production; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0032754; P:positive regulation of interleukin-5 production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0002830; P:positive regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IL34_HUMAN              Reviewed;         242 AA.
AC   Q6ZMJ4; B2RC28; B2Z4A8; B2ZC70; Q8N6L2;
DE   RecName: Full=Interleukin-34;
DE            Short=IL-34;
DE   Flags: Precursor;
GN   Name=IL34; Synonyms=C16orf77;
DR   GO; GO:0005157; F:macrophage colony-stimulating factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
//
ID   IL36A_HUMAN             Reviewed;         158 AA.
AC   Q9UHA7; B2RAD9; Q53SR7; Q5BLR4; Q7RTZ8;
DE   RecName: Full=Interleukin-36 alpha;
DE   AltName: Full=FIL1 epsilon;
DE   AltName: Full=Interleukin-1 epsilon;
DE            Short=IL-1 epsilon;
DE   AltName: Full=Interleukin-1 family member 6;
DE            Short=IL-1F6;
GN   Name=IL36A; Synonyms=FIL1E, IL1E, IL1F6;
DR   GO; GO:0005149; F:interleukin-1 receptor binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
//
ID   IL36B_HUMAN             Reviewed;         164 AA.
AC   Q9NZH7; Q3MIH0; Q53SR6; Q7RTZ7; Q9UHA5;
DE   RecName: Full=Interleukin-36 beta;
DE   AltName: Full=FIL1 eta;
DE   AltName: Full=Interleukin-1 eta;
DE            Short=IL-1 eta;
DE   AltName: Full=Interleukin-1 family member 8;
DE            Short=IL-1F8;
DE   AltName: Full=Interleukin-1 homolog 2;
DE            Short=IL-1H2;
GN   Name=IL36B; Synonyms=IL1F8, IL1H2;
DR   GO; GO:0005149; F:interleukin-1 receptor binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
//
ID   IL36G_HUMAN             Reviewed;         169 AA.
AC   Q9NZH8; Q56B91; Q6UVX7; Q7RTZ9;
DE   RecName: Full=Interleukin-36 gamma;
DE   AltName: Full=IL-1-related protein 2;
DE            Short=IL-1RP2;
DE   AltName: Full=Interleukin-1 epsilon;
DE            Short=IL-1 epsilon;
DE   AltName: Full=Interleukin-1 family member 9;
DE            Short=IL-1F9;
DE   AltName: Full=Interleukin-1 homolog 1;
DE            Short=IL-1H1;
GN   Name=IL36G; Synonyms=IL1E, IL1F9, IL1H1, IL1RP2;
GN   ORFNames=UNQ2456/PRO5737;
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
//
ID   IL37_HUMAN              Reviewed;         218 AA.
AC   Q9NZH6; B5BU97; Q56AP9; Q8TD04; Q8TD05; Q9HBF2; Q9HBF3; Q9UHA6;
DE   RecName: Full=Interleukin-37;
DE   AltName: Full=FIL1 zeta;
DE   AltName: Full=IL-1X;
DE   AltName: Full=Interleukin-1 family member 7;
DE            Short=IL-1F7;
DE   AltName: Full=Interleukin-1 homolog 4;
DE            Short=IL-1H;
DE            Short=IL-1H4;
DE   AltName: Full=Interleukin-1 zeta;
DE            Short=IL-1 zeta;
DE   AltName: Full=Interleukin-1-related protein;
DE            Short=IL-1RP1;
DE   AltName: Full=Interleukin-23;
DE            Short=IL-37;
DE   Flags: Precursor;
GN   Name=IL37; Synonyms=FIL1Z, IL1F7, IL1H4, IL1RP1;
DR   GO; GO:0005149; F:interleukin-1 receptor binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
//
ID   IL3RA_HUMAN             Reviewed;         378 AA.
AC   P26951; A8K3F3; B9VI81; Q5HYQ7;
DE   RecName: Full=Interleukin-3 receptor subunit alpha;
DE            Short=IL-3 receptor subunit alpha;
DE            Short=IL-3R subunit alpha;
DE            Short=IL-3R-alpha;
DE            Short=IL-3RA;
DE   AltName: CD_antigen=CD123;
DE   Flags: Precursor;
GN   Name=IL3RA; Synonyms=IL3R;
DR   GuidetoPHARMACOLOGY; 1705; -.
DR   GO; GO:0004912; F:interleukin-3 receptor activity; TAS:ProtInc.
DR   GO; GO:0036016; P:cellular response to interleukin-3; TAS:GOC.
DR   GO; GO:0038156; P:interleukin-3-mediated signaling pathway; TAS:GOC.
//
ID   IL3RB_HUMAN             Reviewed;         897 AA.
AC   P32927; Q5JZI1; Q6ICE0;
DE   RecName: Full=Cytokine receptor common subunit beta;
DE   AltName: Full=CDw131;
DE   AltName: Full=GM-CSF/IL-3/IL-5 receptor common beta subunit;
DE   AltName: CD_antigen=CD131;
DE   Flags: Precursor;
GN   Name=CSF2RB; Synonyms=IL3RB, IL5RB;
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0036016; P:cellular response to interleukin-3; TAS:GOC.
DR   GO; GO:0038156; P:interleukin-3-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0038043; P:interleukin-5-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   IL3_HUMAN               Reviewed;         152 AA.
AC   P08700; Q6GS87;
DE   RecName: Full=Interleukin-3;
DE            Short=IL-3;
DE   AltName: Full=Hematopoietic growth factor;
DE   AltName: Full=Mast cell growth factor;
DE            Short=MCGF;
DE   AltName: Full=Multipotential colony-stimulating factor;
DE   AltName: Full=P-cell-stimulating factor;
DE   Flags: Precursor;
GN   Name=IL3;
DR   GO; GO:0005135; F:interleukin-3 receptor binding; TAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IDA:DFLAT.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
//
ID   IL4RA_HUMAN             Reviewed;         825 AA.
AC   P24394; B4E076; B9EKU8; H3BSY5; Q96P01; Q9H181; Q9H182; Q9H183;
AC   Q9H184; Q9H185; Q9H186; Q9H187; Q9H188;
DE   RecName: Full=Interleukin-4 receptor subunit alpha;
DE            Short=IL-4 receptor subunit alpha;
DE            Short=IL-4R subunit alpha;
DE            Short=IL-4R-alpha;
DE            Short=IL-4RA;
DE   AltName: CD_antigen=CD124;
DE   Contains:
DE     RecName: Full=Soluble interleukin-4 receptor subunit alpha;
DE              Short=Soluble IL-4 receptor subunit alpha;
DE              Short=Soluble IL-4R-alpha;
DE              Short=sIL4Ralpha/prot;
DE     AltName: Full=IL-4-binding protein;
DE              Short=IL4-BP;
DE   Flags: Precursor;
GN   Name=IL4R; Synonyms=IL4RA; ORFNames=582J2.1;
DR   GO; GO:0004913; F:interleukin-4 receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0035771; P:interleukin-4-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0045626; P:negative regulation of T-helper 1 cell differentiation; IEA:Ensembl.
DR   GO; GO:0030728; P:ovulation; IEA:Ensembl.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IEA:Ensembl.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0002532; P:production of molecular mediator involved in inflammatory response; IEA:InterPro.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IL4_HUMAN               Reviewed;         153 AA.
AC   P05112; Q14630; Q6NZ77;
DE   RecName: Full=Interleukin-4;
DE            Short=IL-4;
DE   AltName: Full=B-cell stimulatory factor 1;
DE            Short=BSF-1;
DE   AltName: Full=Binetrakin;
DE   AltName: Full=Lymphocyte stimulatory factor 1;
DE   AltName: Full=Pitrakinra;
DE   Flags: Precursor;
GN   Name=IL4;
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0005136; F:interleukin-4 receptor binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031296; P:B cell costimulation; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0071288; P:cellular response to mercury ion; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0008203; P:cholesterol metabolic process; ISS:UniProtKB.
DR   GO; GO:0045189; P:connective tissue growth factor biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0097028; P:dendritic cell differentiation; IDA:DFLAT.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002227; P:innate immune response in mucosa; IEA:Ensembl.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0002677; P:negative regulation of chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043031; P:negative regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:2000320; P:negative regulation of T-helper 17 cell differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032736; P:positive regulation of interleukin-13 production; IDA:UniProtKB.
DR   GO; GO:0048295; P:positive regulation of isotype switching to IgE isotypes; ISS:UniProtKB.
DR   GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; ISS:UniProtKB.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IDA:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; ISS:UniProtKB.
DR   GO; GO:0045191; P:regulation of isotype switching; TAS:UniProtKB.
DR   GO; GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.
DR   GO; GO:0010155; P:regulation of proton transport; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0002296; P:T-helper 1 cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0035745; P:T-helper 2 cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0045064; P:T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0042092; P:type 2 immune response; TAS:UniProtKB.
//
ID   IL5RA_HUMAN             Reviewed;         420 AA.
AC   Q01344; B3IU77; B4E2G0; Q14633; Q15469; Q6ISX9;
DE   RecName: Full=Interleukin-5 receptor subunit alpha;
DE            Short=IL-5 receptor subunit alpha;
DE            Short=IL-5R subunit alpha;
DE            Short=IL-5R-alpha;
DE            Short=IL-5RA;
DE   AltName: Full=CDw125;
DE   AltName: CD_antigen=CD125;
DE   Flags: Precursor;
GN   Name=IL5RA; Synonyms=IL5R;
DR   GuidetoPHARMACOLOGY; 1706; -.
DR   GO; GO:0004914; F:interleukin-5 receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0038043; P:interleukin-5-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0032674; P:regulation of interleukin-5 production; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IL5_HUMAN               Reviewed;         134 AA.
AC   P05113; Q13840;
DE   RecName: Full=Interleukin-5;
DE            Short=IL-5;
DE   AltName: Full=B-cell differentiation factor I;
DE   AltName: Full=Eosinophil differentiation factor;
DE   AltName: Full=T-cell replacing factor;
DE            Short=TRF;
DE   Flags: Precursor;
GN   Name=IL5;
DR   GO; GO:0005137; F:interleukin-5 receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0045645; P:positive regulation of eosinophil differentiation; IEA:Ensembl.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0071803; P:positive regulation of podosome assembly; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   IL6RA_HUMAN             Reviewed;         468 AA.
AC   P08887; A8KAE8; B2R6V4; Q16202; Q53EQ7; Q5FWG2; Q5VZ23;
DE   RecName: Full=Interleukin-6 receptor subunit alpha;
DE            Short=IL-6 receptor subunit alpha;
DE            Short=IL-6R subunit alpha;
DE            Short=IL-6R-alpha;
DE            Short=IL-6RA;
DE   AltName: Full=IL-6R 1;
DE   AltName: Full=Membrane glycoprotein 80;
DE            Short=gp80;
DE   AltName: CD_antigen=CD126;
DE   Flags: Precursor;
GN   Name=IL6R;
DR   GO; GO:0070119; F:ciliary neurotrophic factor binding; IPI:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0019981; F:interleukin-6 binding; IPI:BHF-UCL.
DR   GO; GO:0004915; F:interleukin-6 receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; TAS:BHF-UCL.
DR   GO; GO:0070120; P:ciliary neurotrophic factor-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEP:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEP:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; IMP:BHF-UCL.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0002384; P:hepatic immune response; TAS:BHF-UCL.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002548; P:monocyte chemotaxis; IC:BHF-UCL.
DR   GO; GO:0032966; P:negative regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032717; P:negative regulation of interleukin-8 production; IEP:BHF-UCL.
DR   GO; GO:0002446; P:neutrophil mediated immunity; IC:BHF-UCL.
DR   GO; GO:0010536; P:positive regulation of activation of Janus kinase activity; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IC:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; TAS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:BHF-UCL.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
//
ID   IL6RB_HUMAN             Reviewed;         918 AA.
AC   P40189; A0N0L4; Q5FC04; Q9UQ41;
DE   RecName: Full=Interleukin-6 receptor subunit beta;
DE            Short=IL-6 receptor subunit beta;
DE            Short=IL-6R subunit beta;
DE            Short=IL-6R-beta;
DE            Short=IL-6RB;
DE   AltName: Full=CDw130;
DE   AltName: Full=Interleukin-6 signal transducer;
DE   AltName: Full=Membrane glycoprotein 130;
DE            Short=gp130;
DE   AltName: Full=Oncostatin-M receptor subunit alpha;
DE   AltName: CD_antigen=CD130;
DE   Flags: Precursor;
GN   Name=IL6ST;
DR   GO; GO:0004897; F:ciliary neurotrophic factor receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005127; F:ciliary neurotrophic factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0004921; F:interleukin-11 receptor activity; IEA:Ensembl.
DR   GO; GO:0045509; F:interleukin-27 receptor activity; IC:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:BHF-UCL.
DR   GO; GO:0070120; P:ciliary neurotrophic factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:Ensembl.
DR   GO; GO:0070106; P:interleukin-27-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0048861; P:leukemia inhibitory factor signaling pathway; IGI:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:BHF-UCL.
DR   GO; GO:0070104; P:negative regulation of interleukin-6-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0038165; P:oncostatin-M-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IC:BHF-UCL.
DR   GO; GO:0002821; P:positive regulation of adaptive immune response; IC:BHF-UCL.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; TAS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:BHF-UCL.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; TAS:BHF-UCL.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IL6_HUMAN               Reviewed;         212 AA.
AC   P05231; Q9UCU2; Q9UCU3; Q9UCU4;
DE   RecName: Full=Interleukin-6;
DE            Short=IL-6;
DE   AltName: Full=B-cell stimulatory factor 2;
DE            Short=BSF-2;
DE   AltName: Full=CTL differentiation factor;
DE            Short=CDF;
DE   AltName: Full=Hybridoma growth factor;
DE   AltName: Full=Interferon beta-2;
DE            Short=IFN-beta-2;
DE   Flags: Precursor;
GN   Name=IL6; Synonyms=IFNB2;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005138; F:interleukin-6 receptor binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006953; P:acute-phase response; TAS:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:MGI.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEP:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEP:BHF-UCL.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IDA:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; ISS:BHF-UCL.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0070091; P:glucagon secretion; ISS:BHF-UCL.
DR   GO; GO:0002384; P:hepatic immune response; IDA:BHF-UCL.
DR   GO; GO:0006959; P:humoral immune response; IC:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0002548; P:monocyte chemotaxis; IC:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045079; P:negative regulation of chemokine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0032966; P:negative regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0010888; P:negative regulation of lipid storage; NAS:BHF-UCL.
DR   GO; GO:0048635; P:negative regulation of muscle organ development; IEA:Ensembl.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0001781; P:neutrophil apoptotic process; IDA:UniProtKB.
DR   GO; GO:0002446; P:neutrophil mediated immunity; IC:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:BHF-UCL.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; IDA:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IC:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; TAS:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000366; P:positive regulation of STAT protein import into nucleus; IC:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0051971; P:positive regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:2000676; P:positive regulation of type B pancreatic cell apoptotic process; TAS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0045765; P:regulation of angiogenesis; IC:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0045188; P:regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0010574; P:regulation of vascular endothelial growth factor production; IDA:BHF-UCL.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IDA:BHF-UCL.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0032494; P:response to peptidoglycan; IEP:BHF-UCL.
DR   GO; GO:0072540; P:T-helper 17 cell lineage commitment; ISS:UniProtKB.
//
ID   IL7RA_HUMAN             Reviewed;         459 AA.
AC   P16871; B2RCS6; B4DVT1; Q05CU8; Q6NSP4; Q6NWM0; Q6NWM1; Q6NWM2;
AC   Q6NWM3; Q6SV45; Q9UPC1;
DE   RecName: Full=Interleukin-7 receptor subunit alpha;
DE            Short=IL-7 receptor subunit alpha;
DE            Short=IL-7R subunit alpha;
DE            Short=IL-7R-alpha;
DE            Short=IL-7RA;
DE   AltName: Full=CDw127;
DE   AltName: CD_antigen=CD127;
DE   Flags: Precursor;
GN   Name=IL7R;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0004917; F:interleukin-7 receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042100; P:B cell proliferation; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002377; P:immunoglobulin production; IEA:Ensembl.
DR   GO; GO:0038111; P:interleukin-7-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR   GO; GO:0000018; P:regulation of DNA recombination; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
//
ID   IL7_HUMAN               Reviewed;         177 AA.
AC   P13232; A0N0L3; Q5FBY5; Q5FBY9;
DE   RecName: Full=Interleukin-7;
DE            Short=IL-7;
DE   Flags: Precursor;
GN   Name=IL7;
DR   GO; GO:0008083; F:growth factor activity; ISS:UniProtKB.
DR   GO; GO:0005139; F:interleukin-7 receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045453; P:bone resorption; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0002360; P:T cell lineage commitment; IEA:Ensembl.
//
ID   IL8_HUMAN               Reviewed;          99 AA.
AC   P10145; B2R4L8; Q6FGF6; Q6LAE6; Q96RG6; Q9C077; Q9UCE1; Q9UCR8;
AC   Q9UCR9; Q9UCS0;
DE   RecName: Full=Interleukin-8;
DE            Short=IL-8;
DE   AltName: Full=C-X-C motif chemokine 8;
DE   AltName: Full=Chemokine (C-X-C motif) ligand 8;
DE   AltName: Full=Emoctakin;
DE   AltName: Full=Granulocyte chemotactic protein 1;
DE            Short=GCP-1;
DE   AltName: Full=Monocyte-derived neutrophil chemotactic factor;
DE            Short=MDNCF;
DE   AltName: Full=Monocyte-derived neutrophil-activating peptide;
DE            Short=MONAP;
DE   AltName: Full=Neutrophil-activating protein 1;
DE            Short=NAP-1;
DE   AltName: Full=Protein 3-10C;
DE   AltName: Full=T-cell chemotactic factor;
DE   Contains:
DE     RecName: Full=MDNCF-a;
DE     AltName: Full=GCP/IL-8 protein IV;
DE     AltName: Full=IL8/NAP1 form I;
DE   Contains:
DE     RecName: Full=Interleukin-8;
DE     AltName: Full=(Ala-IL-8)77;
DE     AltName: Full=GCP/IL-8 protein II;
DE     AltName: Full=IL-8(1-77);
DE     AltName: Full=IL8/NAP1 form II;
DE     AltName: Full=MDNCF-b;
DE   Contains:
DE     RecName: Full=IL-8(5-77);
DE   Contains:
DE     RecName: Full=IL-8(6-77);
DE     AltName: Full=(Ser-IL-8)72;
DE     AltName: Full=GCP/IL-8 protein I;
DE     AltName: Full=IL8/NAP1 form III;
DE     AltName: Full=Lymphocyte-derived neutrophil-activating factor;
DE              Short=LYNAP;
DE     AltName: Full=MDNCF-c;
DE     AltName: Full=Neutrophil-activating factor;
DE              Short=NAF;
DE   Contains:
DE     RecName: Full=IL-8(7-77);
DE     AltName: Full=GCP/IL-8 protein V;
DE     AltName: Full=IL8/NAP1 form IV;
DE   Contains:
DE     RecName: Full=IL-8(8-77);
DE     AltName: Full=GCP/IL-8 protein VI;
DE     AltName: Full=IL8/NAP1 form V;
DE   Contains:
DE     RecName: Full=IL-8(9-77);
DE     AltName: Full=GCP/IL-8 protein III;
DE     AltName: Full=IL8/NAP1 form VI;
DE   Flags: Precursor;
GN   Name=CXCL8; Synonyms=IL8;
DR   GO; GO:0008009; F:chemokine activity; TAS:UniProtKB.
DR   GO; GO:0005153; F:interleukin-8 receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0001525; P:angiogenesis; TAS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; TAS:UniProtKB.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEP:DFLAT.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IGI:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042119; P:neutrophil activation; TAS:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IGI:UniProtKB.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0045091; P:regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IL9R_HUMAN              Reviewed;         521 AA.
AC   Q01113; B9ZVT0; Q14634; Q8WWU1; Q96TF0;
DE   RecName: Full=Interleukin-9 receptor;
DE            Short=IL-9 receptor;
DE            Short=IL-9R;
DE   AltName: CD_antigen=CD129;
DE   Flags: Precursor;
GN   Name=IL9R;
DR   GO; GO:0004919; F:interleukin-9 receptor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IL9_HUMAN               Reviewed;         144 AA.
AC   P15248;
DE   RecName: Full=Interleukin-9;
DE            Short=IL-9;
DE   AltName: Full=Cytokine P40;
DE   AltName: Full=T-cell growth factor P40;
DE   Flags: Precursor;
GN   Name=IL9;
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045407; P:positive regulation of interleukin-5 biosynthetic process; ISS:UniProtKB.
//
ID   ILDR1_HUMAN             Reviewed;         546 AA.
AC   Q86SU0; Q6ZP61; Q7Z578;
DE   RecName: Full=Immunoglobulin-like domain-containing receptor 1;
DE   Flags: Precursor;
GN   Name=ILDR1;
//
ID   ILDR2_HUMAN             Reviewed;         639 AA.
AC   Q71H61;
DE   RecName: Full=Immunoglobulin-like domain-containing receptor 2;
DE   Flags: Precursor;
GN   Name=ILDR2; Synonyms=C1orf32;
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
//
ID   ILEU_HUMAN              Reviewed;         379 AA.
AC   P30740; A8K5L2; Q53FB9; Q5W0E1; Q9UDF8;
DE   RecName: Full=Leukocyte elastase inhibitor;
DE            Short=LEI;
DE   AltName: Full=Monocyte/neutrophil elastase inhibitor;
DE            Short=EI;
DE            Short=M/NEI;
DE   AltName: Full=Peptidase inhibitor 2;
DE            Short=PI-2;
DE   AltName: Full=Serpin B1;
GN   Name=SERPINB1; Synonyms=ELANH2, MNEI, PI2;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   ILF2_HUMAN              Reviewed;         390 AA.
AC   Q12905; A6NDB0; B2R8G7; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0;
DE   RecName: Full=Interleukin enhancer-binding factor 2;
DE   AltName: Full=Nuclear factor of activated T-cells 45 kDa;
GN   Name=ILF2; Synonyms=NF45; ORFNames=PRO3063;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   ILF3_HUMAN              Reviewed;         894 AA.
AC   Q12906; A8K6F2; G5E9M5; O43409; Q6P1X1; Q86XY7; Q99544; Q99545;
AC   Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0;
AC   Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84;
AC   Q9UNA2;
DE   RecName: Full=Interleukin enhancer-binding factor 3;
DE   AltName: Full=Double-stranded RNA-binding protein 76;
DE            Short=DRBP76;
DE   AltName: Full=M-phase phosphoprotein 4;
DE            Short=MPP4;
DE   AltName: Full=Nuclear factor associated with dsRNA;
DE            Short=NFAR;
DE   AltName: Full=Nuclear factor of activated T-cells 90 kDa;
DE            Short=NF-AT-90;
DE   AltName: Full=Translational control protein 80;
DE            Short=TCP80;
GN   Name=ILF3; Synonyms=DRBF, MPHOSPH4, NF90;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0000279; P:M phase; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ILFT1_HUMAN             Reviewed;         388 AA.
AC   Q8N9Z9; B4DL27; B4DY70; Q8IY38;
DE   RecName: Full=Intermediate filament tail domain-containing protein 1;
GN   Name=IFLTD1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
//
ID   ILKAP_HUMAN             Reviewed;         392 AA.
AC   Q9H0C8; B3KM39;
DE   RecName: Full=Integrin-linked kinase-associated serine/threonine phosphatase 2C;
DE            Short=ILKAP;
DE            EC=3.1.3.16;
GN   Name=ILKAP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0033262; P:regulation of nuclear cell cycle DNA replication; IEA:Ensembl.
//
ID   ILK_HUMAN               Reviewed;         452 AA.
AC   Q13418; B7Z418; D3DQU0; P57043; Q68DZ3;
DE   RecName: Full=Integrin-linked protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=59 kDa serine/threonine-protein kinase;
DE   AltName: Full=ILK-1;
DE   AltName: Full=ILK-2;
DE   AltName: Full=p59ILK;
GN   Name=ILK; Synonyms=ILK1, ILK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0043206; P:extracellular fibril organization; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:MGI.
DR   GO; GO:0032288; P:myelin assembly; IEA:Ensembl.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
//
ID   ILRL1_HUMAN             Reviewed;         556 AA.
AC   Q01638; A8K6B3; B4E0I3; Q53TU7; Q8NEJ3; Q9ULV7; Q9UQ44;
DE   RecName: Full=Interleukin-1 receptor-like 1;
DE   AltName: Full=Protein ST2;
DE   Flags: Precursor;
GN   Name=IL1RL1; Synonyms=DER4, ST2, T1;
DR   GO; GO:0004896; F:cytokine receptor activity; TAS:UniProtKB.
DR   GO; GO:0004908; F:interleukin-1 receptor activity; IEA:InterPro.
DR   GO; GO:0002114; F:interleukin-33 receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0002826; P:negative regulation of T-helper 1 type immune response; IEA:Ensembl.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032754; P:positive regulation of interleukin-5 production; IEA:Ensembl.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ILRL2_HUMAN             Reviewed;         575 AA.
AC   Q9HB29; Q13525; Q45H74; Q53TU8; Q587I8;
DE   RecName: Full=Interleukin-1 receptor-like 2;
DE   AltName: Full=IL-36 receptor;
DE            Short=IL-36R;
DE   AltName: Full=Interleukin-1 receptor-related protein 2;
DE            Short=IL-1Rrp2;
DE            Short=IL1R-rp2;
DE   Flags: Precursor;
GN   Name=IL1RL2; Synonyms=IL1RRP2;
DR   GO; GO:0004908; F:interleukin-1 receptor activity; TAS:ProtInc.
DR   GO; GO:0004909; F:interleukin-1, Type I, activating receptor activity; IEA:InterPro.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ILVBL_HUMAN             Reviewed;         632 AA.
AC   A1L0T0; O43341; Q96F08; Q99651; Q9BWN5; Q9UEB2;
DE   RecName: Full=Acetolactate synthase-like protein;
DE            EC=2.2.1.-;
DE   AltName: Full=IlvB-like protein;
GN   Name=ILVBL; Synonyms=AHAS;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
//
ID   IMA1_HUMAN              Reviewed;         529 AA.
AC   P52292; B9EJD6; Q53YE3; Q9BRU5;
DE   RecName: Full=Importin subunit alpha-1;
DE   AltName: Full=Karyopherin subunit alpha-2;
DE   AltName: Full=RAG cohort protein 1;
DE   AltName: Full=SRP1-alpha;
GN   Name=KPNA2; Synonyms=RCH1, SRP1;
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0000085; P:mitotic G2 phase; TAS:ProtInc.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0000018; P:regulation of DNA recombination; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IMA3_HUMAN              Reviewed;         521 AA.
AC   O00629; A8K4S6; D3DNM2; O00190;
DE   RecName: Full=Importin subunit alpha-3;
DE   AltName: Full=Importin alpha Q1;
DE            Short=Qip1;
DE   AltName: Full=Karyopherin subunit alpha-4;
GN   Name=KPNA4; Synonyms=QIP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
//
ID   IMA4_HUMAN              Reviewed;         521 AA.
AC   O00505; O00191; O43195; Q5JVM9; Q96AA7;
DE   RecName: Full=Importin subunit alpha-4;
DE   AltName: Full=Importin alpha Q2;
DE            Short=Qip2;
DE   AltName: Full=Karyopherin subunit alpha-3;
DE   AltName: Full=SRP1-gamma;
GN   Name=KPNA3; Synonyms=QIP2;
DR   GO; GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
//
ID   IMA5_HUMAN              Reviewed;         538 AA.
AC   P52294; D3DN93; Q6IBQ9; Q9BQ56;
DE   RecName: Full=Importin subunit alpha-5;
DE   AltName: Full=Karyopherin subunit alpha-1;
DE   AltName: Full=Nucleoprotein interactor 1;
DE            Short=NPI-1;
DE   AltName: Full=RAG cohort protein 2;
DE   AltName: Full=SRP1-beta;
DE   Contains:
DE     RecName: Full=Importin subunit alpha-5, N-terminally processed;
GN   Name=KPNA1; Synonyms=RCH2;
DR   GO; GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0000018; P:regulation of DNA recombination; TAS:ProtInc.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   IMA6_HUMAN              Reviewed;         536 AA.
AC   O15131; B2RAI5; Q86X23;
DE   RecName: Full=Importin subunit alpha-6;
DE   AltName: Full=Karyopherin subunit alpha-5;
GN   Name=KPNA5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
//
ID   IMA7_HUMAN              Reviewed;         536 AA.
AC   O60684; B2RDC7; D3DPP5; Q5VVU3;
DE   RecName: Full=Importin subunit alpha-7;
DE   AltName: Full=Karyopherin subunit alpha-6;
GN   Name=KPNA6; Synonyms=IPOA7;
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   IMA8_HUMAN              Reviewed;         516 AA.
AC   A9QM74; A4D277;
DE   RecName: Full=Importin subunit alpha-8;
DE   AltName: Full=Karyopherin subunit alpha-7;
GN   Name=KPNA7;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
//
ID   IMB1_HUMAN              Reviewed;         876 AA.
AC   Q14974; B7ZAV6; D3DTT3; Q14637; Q53XN2; Q96J27;
DE   RecName: Full=Importin subunit beta-1;
DE   AltName: Full=Importin-90;
DE   AltName: Full=Karyopherin subunit beta-1;
DE   AltName: Full=Nuclear factor p97;
DE   AltName: Full=Pore targeting complex 97 kDa subunit;
DE            Short=PTAC97;
GN   Name=KPNB1; Synonyms=NTF97;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:MGI.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.
DR   GO; GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   IMDH1_HUMAN             Reviewed;         514 AA.
AC   P20839; A4D0Z6; A4D0Z7; A6NDW5; A6NNI6; B3KNP7; B3KVM8; B4DE09;
AC   C9JV30; J3KNX8; Q8N194; Q96NU2;
DE   RecName: Full=Inosine-5'-monophosphate dehydrogenase 1;
DE            Short=IMP dehydrogenase 1;
DE            Short=IMPD 1;
DE            Short=IMPDH 1;
DE            EC=1.1.1.205;
DE   AltName: Full=IMPDH-I;
GN   Name=IMPDH1; Synonyms=IMPD1;
DR   GuidetoPHARMACOLOGY; 2624; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003676; F:nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0046651; P:lymphocyte proliferation; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IMDH2_HUMAN             Reviewed;         514 AA.
AC   P12268; Q6LEF3;
DE   RecName: Full=Inosine-5'-monophosphate dehydrogenase 2;
DE            Short=IMP dehydrogenase 2;
DE            Short=IMPD 2;
DE            Short=IMPDH 2;
DE            EC=1.1.1.205;
DE   AltName: Full=IMPDH-II;
GN   Name=IMPDH2; Synonyms=IMPD2;
DR   GuidetoPHARMACOLOGY; 2625; -.
DR   GO; GO:0030554; F:adenyl nucleotide binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IMMT_HUMAN              Reviewed;         758 AA.
AC   Q16891; B1H0U5; B2R5N6; Q14539; Q15092; Q68D41; Q69HW5; Q6IBL0;
AC   Q7Z3X1; Q8TAJ5; Q9P0V2;
DE   RecName: Full=Mitochondrial inner membrane protein;
DE   AltName: Full=Cell proliferation-inducing gene 4/52 protein;
DE   AltName: Full=Mitofilin;
DE   AltName: Full=p87/89;
GN   Name=IMMT; Synonyms=HMP, MINOS2; ORFNames=PIG4, PIG52;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
//
ID   IMP1L_HUMAN             Reviewed;         166 AA.
AC   Q96LU5; D3DQZ7; Q96SH9;
DE   RecName: Full=Mitochondrial inner membrane protease subunit 1;
DE            EC=3.4.21.-;
DE   AltName: Full=IMP1-like protein;
GN   Name=IMMP1L;
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
//
ID   IMP2L_HUMAN             Reviewed;         175 AA.
AC   Q96T52; Q75MF1; Q75MN9; Q75MP0; Q75MS5; Q75MS8; Q96HJ2;
DE   RecName: Full=Mitochondrial inner membrane protease subunit 2;
DE            EC=3.4.21.-;
DE   AltName: Full=IMP2-like protein;
GN   Name=IMMP2L;
DR   GO; GO:0008233; F:peptidase activity; ISS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0030728; P:ovulation; IEA:Ensembl.
DR   GO; GO:0006627; P:protein processing involved in protein targeting to mitochondrion; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   IMP3_HUMAN              Reviewed;         184 AA.
AC   Q9NV31; B3KQ67; Q53G10;
DE   RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP3;
DE            Short=U3 snoRNP protein IMP3;
DE   AltName: Full=BRMS2;
GN   Name=IMP3; Synonyms=C15orf12, MRPS4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   IMP4_HUMAN              Reviewed;         291 AA.
AC   Q96G21; Q3ZTT3;
DE   RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP4;
DE            Short=U3 snoRNP protein IMP4;
DE   AltName: Full=Brix domain-containing protein 4;
GN   Name=IMP4; Synonyms=BXDC4;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006364; P:rRNA processing; NAS:HGNC.
//
ID   IMPA1_HUMAN             Reviewed;         277 AA.
AC   P29218; B2R733; B4DLN3; B7Z6Q4; J3KQT7; Q9UK71;
DE   RecName: Full=Inositol monophosphatase 1;
DE            Short=IMP 1;
DE            Short=IMPase 1;
DE            EC=3.1.3.25;
DE   AltName: Full=Inositol-1(or 4)-monophosphatase 1;
DE   AltName: Full=Lithium-sensitive myo-inositol monophosphatase A1;
GN   Name=IMPA1; Synonyms=IMPA;
DR   GuidetoPHARMACOLOGY; 1463; -.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008934; F:inositol monophosphate 1-phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0052832; F:inositol monophosphate 3-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052833; F:inositol monophosphate 4-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:MGI.
DR   GO; GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IDA:MGI.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; IMP:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IMPA2_HUMAN             Reviewed;         288 AA.
AC   O14732; B0YJ29; Q9UJT3;
DE   RecName: Full=Inositol monophosphatase 2;
DE            Short=IMP 2;
DE            Short=IMPase 2;
DE            EC=3.1.3.25;
DE   AltName: Full=Inositol-1(or 4)-monophosphatase 2;
DE   AltName: Full=Myo-inositol monophosphatase A2;
GN   Name=IMPA2; Synonyms=IMP.18P;
DR   GO; GO:0008934; F:inositol monophosphate 1-phosphatase activity; IDA:MGI.
DR   GO; GO:0052832; F:inositol monophosphate 3-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052833; F:inositol monophosphate 4-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:MGI.
DR   GO; GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IDA:MGI.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IMPA3_HUMAN             Reviewed;         359 AA.
AC   Q9NX62; Q6NVY7;
DE   RecName: Full=Inositol monophosphatase 3;
DE            Short=IMP 3;
DE            Short=IMPase 3;
DE            EC=3.1.3.25;
DE            EC=3.1.3.7;
DE   AltName: Full=Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase;
DE            Short=Golgi-resident PAP phosphatase;
DE            Short=gPAPP;
DE   AltName: Full=Inositol monophosphatase domain-containing protein 1;
DE   AltName: Full=Inositol-1(or 4)-monophosphatase 3;
DE   AltName: Full=Myo-inositol monophosphatase A3;
GN   Name=IMPAD1; Synonyms=IMPA3;
DR   GO; GO:0008441; F:3'(2'),5'-bisphosphate nucleotidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008254; F:3'-nucleotidase activity; IEA:Ensembl.
DR   GO; GO:0008934; F:inositol monophosphate 1-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052832; F:inositol monophosphate 3-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052833; F:inositol monophosphate 4-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
//
ID   IMPCT_HUMAN             Reviewed;         320 AA.
AC   Q9P2X3; A8MXG0; Q49AM0; Q9H2X4;
DE   RecName: Full=Protein IMPACT;
DE   AltName: Full=Imprinted and ancient gene protein homolog;
GN   Name=IMPACT;
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:Ensembl.
//
ID   IMPG1_HUMAN             Reviewed;         797 AA.
AC   Q17R60; A6NNZ6; O43686; O95094; Q9BWZ1;
DE   RecName: Full=Interphotoreceptor matrix proteoglycan 1;
DE   AltName: Full=Interphotoreceptor matrix proteoglycan of 150 kDa;
DE            Short=IPM-150;
DE   AltName: Full=Sialoprotein associated with cones and rods;
DE   Flags: Precursor;
GN   Name=IMPG1; Synonyms=IPM150, SPACR;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   IMPG2_HUMAN             Reviewed;        1241 AA.
AC   Q9BZV3; A8MWT5; Q9UKD4; Q9UKK5;
DE   RecName: Full=Interphotoreceptor matrix proteoglycan 2;
DE   AltName: Full=Interphotoreceptor matrix proteoglycan of 200 kDa;
DE            Short=IPM 200;
DE   AltName: Full=Sialoprotein associated with cones and rods proteoglycan;
DE            Short=Spacrcan;
DE   Flags: Precursor;
GN   Name=IMPG2; Synonyms=IPM200;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005540; F:hyaluronic acid binding; TAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:UniProtKB.
//
ID   IMUP_HUMAN              Reviewed;         106 AA.
AC   Q9GZP8; Q0P6G2; Q96H58; Q9HCR4;
DE   RecName: Full=Immortalization up-regulated protein;
DE   AltName: Full=Hepatocyte growth factor activator inhibitor type 2-related small protein;
DE            Short=H2RSP;
DE            Short=HAI-2-related small protein;
GN   Name=IMUP; Synonyms=C19orf33;
//
ID   IN4L1_HUMAN             Reviewed;         439 AA.
AC   Q96LV5;
DE   RecName: Full=Integrator complex subunit 4-like protein 1;
GN   Name=INTS4L1;
//
ID   IN4L2_HUMAN             Reviewed;         439 AA.
AC   Q2T9F4;
DE   RecName: Full=Integrator complex subunit 4-like protein 2;
GN   Name=INTS4L2;
//
ID   IN80B_HUMAN             Reviewed;         356 AA.
AC   Q9C086;
DE   RecName: Full=INO80 complex subunit B;
DE   AltName: Full=High mobility group AT-hook 1-like 4;
DE   AltName: Full=IES2 homolog;
DE            Short=hIes2;
DE   AltName: Full=PAP-1-associated protein 1;
DE            Short=PAPA-1;
DE   AltName: Full=Zinc finger HIT domain-containing protein 4;
GN   Name=INO80B; Synonyms=HMGA1L4, PAPA1, ZNHIT4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IN35_HUMAN              Reviewed;         286 AA.
AC   P80217; C9JGX1; Q92984; Q99537; Q9BV98;
DE   RecName: Full=Interferon-induced 35 kDa protein;
DE            Short=IFP 35;
DE            Short=Ifi-35;
GN   Name=IFI35; Synonyms=IFP35;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IN80D_HUMAN             Reviewed;         878 AA.
AC   Q53TQ3; B3KU68; B9EG77; Q6PJC6; Q6PJU1; Q6PKA1; Q9NXD5;
DE   RecName: Full=INO80 complex subunit D;
GN   Name=INO80D;
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IN80C_HUMAN             Reviewed;         192 AA.
AC   Q6PI98; B4DUI4; E9PCS7; Q86WR1; Q8N994;
DE   RecName: Full=INO80 complex subunit C;
DE   AltName: Full=IES6 homolog;
DE            Short=hIes6;
GN   Name=INO80C; Synonyms=C18orf37;
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IN80E_HUMAN             Reviewed;         244 AA.
AC   Q8NBZ0;
DE   RecName: Full=INO80 complex subunit E;
DE   AltName: Full=Coiled-coil domain-containing protein 95;
GN   Name=INO80E; Synonyms=CCDC95;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   INADL_HUMAN             Reviewed;        1801 AA.
AC   Q8NI35; O15249; O43742; O60833; Q5VUA5; Q5VUA6; Q5VUA7; Q5VUA8;
AC   Q5VUA9; Q5VUB0; Q8WU78; Q9H3N9;
DE   RecName: Full=InaD-like protein;
DE            Short=Inadl protein;
DE            Short=hINADL;
DE   AltName: Full=Pals1-associated tight junction protein;
DE   AltName: Full=Protein associated to tight junctions;
GN   Name=INADL; Synonyms=PATJ;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   INAR1_HUMAN             Reviewed;         557 AA.
AC   P17181; B2R6L9; D3DSF0; Q53GW9; Q53H11; Q6PKD7; Q7M4L2; Q8WTZ2;
DE   RecName: Full=Interferon alpha/beta receptor 1;
DE            Short=IFN-R-1;
DE            Short=IFN-alpha/beta receptor 1;
DE   AltName: Full=Cytokine receptor class-II member 1;
DE   AltName: Full=Cytokine receptor family 2 member 1;
DE            Short=CRF2-1;
DE   AltName: Full=Type I interferon receptor 1;
DE   Flags: Precursor;
GN   Name=IFNAR1; Synonyms=IFNAR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004905; F:type I interferon receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0045351; P:type I interferon biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   INAR2_HUMAN             Reviewed;         515 AA.
AC   P48551; A8KAJ4; D3DSE8; D3DSE9; Q15467; Q6FHD7;
DE   RecName: Full=Interferon alpha/beta receptor 2;
DE            Short=IFN-R-2;
DE            Short=IFN-alpha binding protein;
DE            Short=IFN-alpha/beta receptor 2;
DE   AltName: Full=Interferon alpha binding protein;
DE   AltName: Full=Type I interferon receptor 2;
DE   Flags: Precursor;
GN   Name=IFNAR2; Synonyms=IFNABR, IFNARB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019962; F:type I interferon binding; IPI:UniProtKB.
DR   GO; GO:0004905; F:type I interferon receptor activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   INCA1_HUMAN             Reviewed;         236 AA.
AC   Q0VD86; Q6J273; Q6PKN9;
DE   RecName: Full=Protein INCA1;
DE   AltName: Full=Inhibitor of CDK interacting with cyclin A1;
GN   Name=INCA1; ORFNames=HSD45;
DR   GO; GO:0030332; F:cyclin binding; IDA:MGI.
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:MGI.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
//
ID   INCE_HUMAN              Reviewed;         918 AA.
AC   Q9NQS7; A8MQD2; Q5Y192;
DE   RecName: Full=Inner centromere protein;
GN   Name=INCENP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   INE1_HUMAN              Reviewed;          51 AA.
AC   O15225; Q5JRR7; Q6NSX0;
DE   RecName: Full=Putative inactivation escape 1 protein;
GN   Name=INE1; Synonyms=DXS6974E;
//
ID   INF2_HUMAN              Reviewed;        1249 AA.
AC   Q27J81; Q27J83; Q69YL8; Q6P1X7; Q6PK22; Q86TR7; Q9BRM1; Q9H6N1;
DE   RecName: Full=Inverted formin-2;
DE   AltName: Full=HBEBP2-binding protein C;
GN   Name=INF2; Synonyms=C14orf151, C14orf173;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0032535; P:regulation of cellular component size; IEA:Ensembl.
DR   GO; GO:0090140; P:regulation of mitochondrial fission; IMP:MGI.
//
ID   ING1_HUMAN              Reviewed;         422 AA.
AC   Q9UK53; O00532; O43658; Q53ZR3; Q5T9G8; Q5T9G9; Q5T9H0; Q5T9H1;
AC   Q9H007; Q9HD98; Q9HD99; Q9NS83; Q9P0U6; Q9UBC6; Q9UIJ1; Q9UIJ2;
AC   Q9UIJ3; Q9UIJ4; Q9UK52;
DE   RecName: Full=Inhibitor of growth protein 1;
GN   Name=ING1;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:InterPro.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0010941; P:regulation of cell death; IEA:Ensembl.
//
ID   ING2_HUMAN              Reviewed;         280 AA.
AC   Q9H160; B6ZDS1; O95698;
DE   RecName: Full=Inhibitor of growth protein 2;
DE   AltName: Full=Inhibitor of growth 1-like protein;
DE            Short=ING1Lp;
DE   AltName: Full=p32;
DE   AltName: Full=p33ING2;
GN   Name=ING2; Synonyms=ING1L;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; ISS:BHF-UCL.
DR   GO; GO:0048133; P:male germ-line stem cell division; ISS:BHF-UCL.
DR   GO; GO:0007141; P:male meiosis I; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:InterPro.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; TAS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000772; P:regulation of cellular senescence; NAS:BHF-UCL.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:2001020; P:regulation of response to DNA damage stimulus; NAS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0072520; P:seminiferous tubule development; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0030317; P:sperm motility; ISS:BHF-UCL.
DR   GO; GO:0007286; P:spermatid development; ISS:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ING3_HUMAN              Reviewed;         418 AA.
AC   Q9NXR8; A8K790; O60394; Q567P3; Q6GMT3; Q7Z762; Q969G0; Q96DT4;
AC   Q9HC99; Q9P081;
DE   RecName: Full=Inhibitor of growth protein 3;
DE   AltName: Full=p47ING3;
GN   Name=ING3; ORFNames=HSPC301;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ING4_HUMAN              Reviewed;         249 AA.
AC   Q9UNL4; A4KYM4; A4KYM6; D3DUR8; Q0EF62; Q0EF63; Q4VBQ6; Q96E15;
AC   Q9H3J0;
DE   RecName: Full=Inhibitor of growth protein 4;
DE   AltName: Full=p29ING4;
GN   Name=ING4; ORFNames=My036;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006473; P:protein acetylation; IDA:UniProtKB.
//
ID   ING5_HUMAN              Reviewed;         240 AA.
AC   Q8WYH8; A8K1P3; Q53NU6; Q57Z54; Q9BS30;
DE   RecName: Full=Inhibitor of growth protein 5;
DE   AltName: Full=p28ING5;
GN   Name=ING5;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006473; P:protein acetylation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   INGR1_HUMAN             Reviewed;         489 AA.
AC   P15260; E1P587; Q53Y96;
DE   RecName: Full=Interferon gamma receptor 1;
DE            Short=IFN-gamma receptor 1;
DE            Short=IFN-gamma-R1;
DE   AltName: Full=CDw119;
DE   AltName: CD_antigen=CD119;
DE   Flags: Precursor;
GN   Name=IFNGR1;
DR   GO; GO:0004906; F:interferon-gamma receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   INGR2_HUMAN             Reviewed;         337 AA.
AC   P38484; Q9BTL5;
DE   RecName: Full=Interferon gamma receptor 2;
DE            Short=IFN-gamma receptor 2;
DE            Short=IFN-gamma-R2;
DE   AltName: Full=Interferon gamma receptor accessory factor 1;
DE            Short=AF-1;
DE   AltName: Full=Interferon gamma transducer 1;
DE   Flags: Precursor;
GN   Name=IFNGR2; Synonyms=IFNGT1;
DR   GO; GO:0004906; F:interferon-gamma receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
//
ID   INHA_HUMAN              Reviewed;         366 AA.
AC   P05111; A8K8H5;
DE   RecName: Full=Inhibin alpha chain;
DE   Flags: Precursor;
GN   Name=INHA;
DR   GO; GO:0005125; F:cytokine activity; TAS:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; TAS:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:HGNC.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0045578; P:negative regulation of B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0046882; P:negative regulation of follicle-stimulating hormone secretion; NAS:UniProtKB.
DR   GO; GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; TAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; NAS:UniProtKB.
DR   GO; GO:0046881; P:positive regulation of follicle-stimulating hormone secretion; TAS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:HGNC.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:HGNC.
DR   GO; GO:0009605; P:response to external stimulus; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   INHBA_HUMAN             Reviewed;         426 AA.
AC   P08476; Q14599;
DE   RecName: Full=Inhibin beta A chain;
DE   AltName: Full=Activin beta-A chain;
DE   AltName: Full=Erythroid differentiation protein;
DE            Short=EDF;
DE   Flags: Precursor;
GN   Name=INHBA;
DR   GO; GO:0005125; F:cytokine activity; IDA:HGNC.
DR   GO; GO:0008083; F:growth factor activity; TAS:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; TAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070699; F:type II activin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:HGNC.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0071397; P:cellular response to cholesterol; IEA:Ensembl.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:HGNC.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0001942; P:hair follicle development; IGI:UniProtKB.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IDA:UniProtKB.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IGI:UniProtKB.
DR   GO; GO:0048333; P:mesodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0045578; P:negative regulation of B cell differentiation; TAS:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:HGNC.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0046882; P:negative regulation of follicle-stimulating hormone secretion; NAS:UniProtKB.
DR   GO; GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; TAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; IGI:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IGI:UniProtKB.
DR   GO; GO:0060021; P:palate development; IGI:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:HGNC.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:UniProtKB.
DR   GO; GO:0046881; P:positive regulation of follicle-stimulating hormone secretion; TAS:UniProtKB.
DR   GO; GO:0060279; P:positive regulation of ovulation; ISS:UniProtKB.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042701; P:progesterone secretion; IGI:UniProtKB.
DR   GO; GO:0046880; P:regulation of follicle-stimulating hormone secretion; IGI:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
//
ID   INHBB_HUMAN             Reviewed;         407 AA.
AC   P09529; Q53T31; Q8N1D3;
DE   RecName: Full=Inhibin beta B chain;
DE   AltName: Full=Activin beta-B chain;
DE   Flags: Precursor;
GN   Name=INHBB;
DR   GO; GO:0005125; F:cytokine activity; TAS:UniProtKB.
DR   GO; GO:0005179; F:hormone activity; TAS:UniProtKB.
DR   GO; GO:0046789; F:host cell surface receptor binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0044320; P:cellular response to leptin stimulus; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0046882; P:negative regulation of follicle-stimulating hormone secretion; IPI:UniProtKB.
DR   GO; GO:0048178; P:negative regulation of hepatocyte growth factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; NAS:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0046881; P:positive regulation of follicle-stimulating hormone secretion; IPI:UniProtKB.
DR   GO; GO:0060279; P:positive regulation of ovulation; ISS:UniProtKB.
DR   GO; GO:0009612; P:response to mechanical stimulus; IDA:UniProtKB.
//
ID   INHBC_HUMAN             Reviewed;         352 AA.
AC   P55103; A1L3Y2;
DE   RecName: Full=Inhibin beta C chain;
DE   AltName: Full=Activin beta-C chain;
DE   Flags: Precursor;
GN   Name=INHBC;
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; TAS:ProtInc.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
//
ID   INHBE_HUMAN             Reviewed;         350 AA.
AC   P58166;
DE   RecName: Full=Inhibin beta E chain;
DE   AltName: Full=Activin beta-E chain;
DE   Flags: Precursor;
GN   Name=INHBE;
DR   GO; GO:0040007; P:growth; IEA:InterPro.
//
ID   INLR1_HUMAN             Reviewed;         520 AA.
AC   Q8IU57; Q5VTX5; Q5VTX7; Q5VTX8; Q6ZML8; Q8IV66; Q8IZI7; Q8IZI8;
DE   RecName: Full=Interferon lambda receptor 1;
DE            Short=IFN-lambda receptor 1;
DE            Short=IFN-lambda-R1;
DE   AltName: Full=Cytokine receptor class-II member 12;
DE   AltName: Full=Cytokine receptor family 2 member 12;
DE            Short=CRF2-12;
DE   AltName: Full=Interleukin-28 receptor subunit alpha;
DE            Short=IL-28 receptor subunit alpha;
DE            Short=IL-28R-alpha;
DE            Short=IL-28RA;
DE   AltName: Full=Likely interleukin or cytokine receptor 2;
DE            Short=LICR2;
DE   Flags: Precursor;
GN   Name=IFNLR1; Synonyms=IL28RA, LICR2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:GOC.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0002385; P:mucosal immune response; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0050691; P:regulation of defense response to virus by host; IDA:UniProtKB.
//
ID   INMT_HUMAN              Reviewed;         263 AA.
AC   O95050; B8ZZ69; Q3KP49; Q9P1Y2; Q9UBY4; Q9UHQ0;
DE   RecName: Full=Indolethylamine N-methyltransferase;
DE            Short=Indolamine N-methyltransferase;
DE            EC=2.1.1.49;
DE            EC=2.1.1.96;
DE   AltName: Full=Aromatic alkylamine N-methyltransferase;
DE            Short=Amine N-methyltransferase;
DE            Short=Arylamine N-methyltransferase;
DE   AltName: Full=Thioether S-methyltransferase;
DE            Short=TEMT;
GN   Name=INMT;
DR   GO; GO:0030748; F:amine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004790; F:thioether S-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009308; P:amine metabolic process; IDA:UniProtKB.
DR   GO; GO:0032259; P:methylation; IDA:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IEA:UniProtKB-KW.
//
ID   INO1_HUMAN              Reviewed;         558 AA.
AC   Q9NPH2; B3KRT1; G5E9U0; Q6NXT5; Q7Z525; Q9BT65; Q9H2Y2; Q9NSU0;
AC   Q9NVW7;
DE   RecName: Full=Inositol-3-phosphate synthase 1;
DE            Short=IPS 1;
DE            EC=5.5.1.4;
DE   AltName: Full=Myo-inositol 1-phosphate synthase;
DE            Short=MI-1-P synthase;
DE            Short=MIP synthase;
DE            Short=hIPS;
DE   AltName: Full=Myo-inositol 1-phosphate synthase A1;
DE            Short=hINO1;
GN   Name=ISYNA1; Synonyms=INO1;
DR   GO; GO:0004512; F:inositol-3-phosphate synthase activity; TAS:Reactome.
DR   GO; GO:0006021; P:inositol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   INO80_HUMAN             Reviewed;        1556 AA.
AC   Q9ULG1; A6H8X4; Q9NTG6;
DE   RecName: Full=DNA helicase INO80;
DE            Short=hINO80;
DE            EC=3.6.4.12;
DE   AltName: Full=INO80 complex subunit A;
DE   AltName: Full=Putative DNA helicase INO80 complex homolog 1;
GN   Name=INO80; Synonyms=INO80A, INOC1, KIAA1259;
DR   GO; GO:0043014; F:alpha-tubulin binding; IMP:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IMP:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
DR   GO; GO:0070914; P:UV-damage excision repair; IMP:UniProtKB.
//
ID   INP4A_HUMAN             Reviewed;         977 AA.
AC   Q96PE3; O15326; Q13187; Q53TD8; Q8TC02;
DE   RecName: Full=Type I inositol 3,4-bisphosphate 4-phosphatase;
DE            EC=3.1.3.66;
DE   AltName: Full=Inositol polyphosphate 4-phosphatase type I;
GN   Name=INPP4A;
DR   GO; GO:0016316; F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034597; F:phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   INP4B_HUMAN             Reviewed;         924 AA.
AC   O15327; Q2TAI2; Q5XLE7; Q6IN59; Q6PJB4;
DE   RecName: Full=Type II inositol 3,4-bisphosphate 4-phosphatase;
DE            EC=3.1.3.66;
DE   AltName: Full=Inositol polyphosphate 4-phosphatase type II;
GN   Name=INPP4B;
DR   GO; GO:0008289; F:lipid binding; IEA:Ensembl.
DR   GO; GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0016316; F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; TAS:ProtInc.
DR   GO; GO:0034597; F:phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0046850; P:regulation of bone remodeling; IEA:Ensembl.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   INP5E_HUMAN             Reviewed;         644 AA.
AC   Q9NRR6; Q15734; Q6PIV5;
DE   RecName: Full=72 kDa inositol polyphosphate 5-phosphatase;
DE            EC=3.1.3.36;
DE   AltName: Full=Phosphatidylinositol 4,5-bisphosphate 5-phosphatase;
DE   AltName: Full=Phosphatidylinositol polyphosphate 5-phosphatase type IV;
GN   Name=INPP5E;
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:UniProtKB.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   INP5K_HUMAN             Reviewed;         448 AA.
AC   Q9BT40; B2R6I2; B2R750; D3DTH8; Q15733; Q9NPJ5; Q9P2R5;
DE   RecName: Full=Inositol polyphosphate 5-phosphatase K;
DE            EC=3.1.3.56;
DE   AltName: Full=Skeletal muscle and kidney-enriched inositol phosphatase;
GN   Name=INPP5K; Synonyms=PPS, SKIP;
DR   GO; GO:0016312; F:inositol bisphosphate phosphatase activity; IDA:MGI.
DR   GO; GO:0046030; F:inositol trisphosphate phosphatase activity; IDA:MGI.
DR   GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042577; F:lipid phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0034595; F:phosphatidylinositol phosphate 5-phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005000; F:vasopressin receptor activity; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; ISS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IDA:MGI.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0035305; P:negative regulation of dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0010829; P:negative regulation of glucose transport; IDA:UniProtKB.
DR   GO; GO:2000466; P:negative regulation of glycogen (starch) synthase activity; ISS:UniProtKB.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0090315; P:negative regulation of protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:0045869; P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; IDA:UniProtKB.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:2001153; P:positive regulation of renal water transport; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0035810; P:positive regulation of urine volume; ISS:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0097178; P:ruffle assembly; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   INPP_HUMAN              Reviewed;         399 AA.
AC   P49441;
DE   RecName: Full=Inositol polyphosphate 1-phosphatase;
DE            Short=IPP;
DE            Short=IPPase;
DE            EC=3.1.3.57;
GN   Name=INPP1;
DR   GO; GO:0052829; F:inositol-1,3,4-trisphosphate 1-phosphatase activity; TAS:Reactome.
DR   GO; GO:0004441; F:inositol-1,4-bisphosphate 1-phosphatase activity; TAS:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   INSC_HUMAN              Reviewed;         579 AA.
AC   Q1MX18; A0PJX5; Q1MX19; Q3C1V6; Q4AC95; Q4AC96; Q4AC97; Q4AC98;
DE   RecName: Full=Protein inscuteable homolog;
GN   Name=INSC;
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:Ensembl.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   INSI1_HUMAN             Reviewed;         277 AA.
AC   O15503; A4D2N1; A8K6L0; Q53XW8; Q9BUV5;
DE   RecName: Full=Insulin-induced gene 1 protein;
DE            Short=INSIG-1;
GN   Name=INSIG1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060363; P:cranial suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:1901303; P:negative regulation of cargo loading into COPII-coated vesicle; IMP:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010894; P:negative regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0032933; P:SREBP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   INSI2_HUMAN             Reviewed;         225 AA.
AC   Q9Y5U4; A8K5W8; Q8TBI8;
DE   RecName: Full=Insulin-induced gene 2 protein;
DE            Short=INSIG-2;
GN   Name=INSIG2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060363; P:cranial suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010894; P:negative regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0032933; P:SREBP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   INSL3_HUMAN             Reviewed;         131 AA.
AC   P51460; B4DZ72; G3XAG0; Q3KPI5; Q3KPI6; Q6YNB5; Q9UEA2; Q9UPH6;
DE   RecName: Full=Insulin-like 3;
DE   AltName: Full=Leydig insulin-like peptide;
DE            Short=Ley-I-L;
DE   AltName: Full=Relaxin-like factor;
DE   Contains:
DE     RecName: Full=Insulin-like 3 B chain;
DE   Contains:
DE     RecName: Full=Insulin-like 3 A chain;
DE   Flags: Precursor;
GN   Name=INSL3; Synonyms=RLF, RLNL;
DR   GO; GO:0005158; F:insulin receptor binding; TAS:ProtInc.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   INSL4_HUMAN             Reviewed;         139 AA.
AC   Q14641; A8K678; Q5W127;
DE   RecName: Full=Early placenta insulin-like peptide;
DE            Short=EPIL;
DE   AltName: Full=Insulin-like peptide 4;
DE   AltName: Full=Placentin;
DE   Contains:
DE     RecName: Full=Early placenta insulin-like peptide B chain;
DE   Contains:
DE     RecName: Full=Early placenta insulin-like peptide A chain;
DE   Flags: Precursor;
GN   Name=INSL4;
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   INSL5_HUMAN             Reviewed;         135 AA.
AC   Q9Y5Q6; Q3MIY4; Q5VYD8;
DE   RecName: Full=Insulin-like peptide INSL5;
DE            Short=Insulin-like peptide 5;
DE   Contains:
DE     RecName: Full=Insulin-like peptide INSL5 B chain;
DE   Contains:
DE     RecName: Full=Insulin-like peptide INSL5 A chain;
DE   Flags: Precursor;
GN   Name=INSL5; ORFNames=UNQ156/PRO182;
//
ID   INSL6_HUMAN             Reviewed;         213 AA.
AC   Q9Y581; A0AVS0; Q9NS16;
DE   RecName: Full=Insulin-like peptide INSL6;
DE            Short=Insulin-like peptide 6;
DE   AltName: Full=Relaxin/insulin-like factor 1;
DE   Contains:
DE     RecName: Full=Insulin-like peptide INSL6 B chain;
DE   Contains:
DE     RecName: Full=Insulin-like peptide INSL6 A chain;
DE   Flags: Precursor;
GN   Name=INSL6; Synonyms=RIF1;
DR   GO; GO:0005179; F:hormone activity; NAS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   INSM1_HUMAN             Reviewed;         510 AA.
AC   Q01101;
DE   RecName: Full=Insulinoma-associated protein 1;
DE   AltName: Full=Zinc finger protein IA-1;
GN   Name=INSM1; Synonyms=IA1;
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0061104; P:adrenal chromaffin cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0003358; P:noradrenergic neuron development; ISS:UniProtKB.
DR   GO; GO:0042421; P:norepinephrine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060290; P:transdifferentiation; IDA:UniProtKB.
DR   GO; GO:0003323; P:type B pancreatic cell development; IEA:Ensembl.
DR   GO; GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB.
//
ID   INSM2_HUMAN             Reviewed;         566 AA.
AC   Q96T92; A1L432; J9Y024; Q8N8K7; Q96Q84;
DE   RecName: Full=Insulinoma-associated protein 2;
DE   AltName: Full=Zinc finger protein IA-6;
GN   Name=INSM2; Synonyms=IA6; ORFNames=Nbla106;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   INSR2_HUMAN             Reviewed;         200 AA.
AC   F8WCM5; Q1WM24;
DE   RecName: Full=Insulin, isoform 2;
DE   AltName: Full=INS-IGF2 readthrough transcript protein;
GN   Name=INS-IGF2;
//
ID   INSRR_HUMAN             Reviewed;        1297 AA.
AC   P14616; O60724; Q5VZS3;
DE   RecName: Full=Insulin receptor-related protein;
DE            Short=IRR;
DE            EC=2.7.10.1;
DE   AltName: Full=IR-related receptor;
DE   Contains:
DE     RecName: Full=Insulin receptor-related protein alpha chain;
DE   Contains:
DE     RecName: Full=Insulin receptor-related protein beta chain;
DE   Flags: Precursor;
GN   Name=INSRR; Synonyms=IRR;
DR   GuidetoPHARMACOLOGY; 1802; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0071469; P:cellular response to alkalinity; IDA:UniProtKB.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB.
//
ID   INSR_HUMAN              Reviewed;        1382 AA.
AC   P06213; Q17RW0; Q59H98; Q9UCB7; Q9UCB8; Q9UCB9;
DE   RecName: Full=Insulin receptor;
DE            Short=IR;
DE            EC=2.7.10.1;
DE   AltName: CD_antigen=CD220;
DE   Contains:
DE     RecName: Full=Insulin receptor subunit alpha;
DE   Contains:
DE     RecName: Full=Insulin receptor subunit beta;
DE   Flags: Precursor;
GN   Name=INSR;
DR   GuidetoPHARMACOLOGY; 1800; -.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0043559; F:insulin binding; IDA:UniProtKB.
DR   GO; GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.
DR   GO; GO:0005009; F:insulin-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.
DR   GO; GO:0031995; F:insulin-like growth factor II binding; IPI:BHF-UCL.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IDA:BHF-UCL.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IMP:UniProtKB.
DR   GO; GO:0051425; F:PTB domain binding; IPI:UniProtKB.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IMP:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0048639; P:positive regulation of developmental growth; IMP:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IMP:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IMP:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060267; P:positive regulation of respiratory burst; IDA:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0051290; P:protein heterotetramerization; IDA:UniProtKB.
DR   GO; GO:0045995; P:regulation of embryonic development; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IDA:GOC.
DR   GO; GO:0019087; P:transformation of host cell by virus; IMP:BHF-UCL.
//
ID   INS_HUMAN               Reviewed;         110 AA.
AC   P01308; Q5EEX2;
DE   RecName: Full=Insulin;
DE   Contains:
DE     RecName: Full=Insulin B chain;
DE   Contains:
DE     RecName: Full=Insulin A chain;
DE   Flags: Precursor;
GN   Name=INS;
DR   GO; GO:0005179; F:hormone activity; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005158; F:insulin receptor binding; IDA:UniProtKB.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IDA:BHF-UCL.
DR   GO; GO:0046631; P:alpha-beta T cell activation; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IC:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0055089; P:fatty acid homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0015758; P:glucose transport; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0045922; P:negative regulation of fatty acid metabolic process; IMP:BHF-UCL.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IDA:DFLAT.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; NAS:BHF-UCL.
DR   GO; GO:0045818; P:negative regulation of glycogen catabolic process; IMP:BHF-UCL.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; NAS:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; NAS:BHF-UCL.
DR   GO; GO:0033861; P:negative regulation of NAD(P)H oxidase activity; IDA:BHF-UCL.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0032460; P:negative regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IMP:BHF-UCL.
DR   GO; GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0045908; P:negative regulation of vasodilation; NAS:UniProtKB.
DR   GO; GO:0090336; P:positive regulation of brown fat cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; NAS:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IDA:BHF-UCL.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; NAS:UniProtKB.
DR   GO; GO:0090277; P:positive regulation of peptide hormone secretion; TAS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; ISS:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0060267; P:positive regulation of respiratory burst; IDA:BHF-UCL.
DR   GO; GO:0045909; P:positive regulation of vasodilation; NAS:UniProtKB.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; IMP:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.
DR   GO; GO:0050708; P:regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:BHF-UCL.
DR   GO; GO:0022898; P:regulation of transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; IDA:BHF-UCL.
//
ID   INT10_HUMAN             Reviewed;         710 AA.
AC   Q9NVR2; Q6IA93; Q7L538; Q7L8C8; Q9H3W8;
DE   RecName: Full=Integrator complex subunit 10;
DE            Short=Int10;
GN   Name=INTS10; Synonyms=C8orf35;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT11_HUMAN             Reviewed;         600 AA.
AC   Q5TA45; A8K5S2; B3KPR3; B4DM87; G3V1S5; Q5TA46; Q5TA48; Q5TA52;
AC   Q5TA53; Q5TA54; Q7L3D7; Q96HY1; Q9BW36; Q9H0F9; Q9H8R5; Q9HAA6;
AC   Q9NWX9;
DE   RecName: Full=Integrator complex subunit 11;
DE            Short=Int11;
DE            EC=3.1.27.-;
DE   AltName: Full=Cleavage and polyadenylation-specific factor 3-like protein;
DE            Short=CPSF3-like protein;
DE   AltName: Full=Protein related to CPSF subunits of 68 kDa;
DE            Short=RC-68;
GN   Name=CPSF3L; Synonyms=INTS11, RC68;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   INT12_HUMAN             Reviewed;         462 AA.
AC   Q96CB8; B2RC48; Q3B6Z3; Q9HD71;
DE   RecName: Full=Integrator complex subunit 12;
DE            Short=Int12;
DE   AltName: Full=PHD finger protein 22;
GN   Name=INTS12; Synonyms=PHF22; ORFNames=SBBI22;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT1_HUMAN              Reviewed;        2190 AA.
AC   Q8N201; A6NJ44; Q6NT70; Q6UX74; Q8WV40; Q96D36; Q9NTD1; Q9P2A8;
AC   Q9Y3W8;
DE   RecName: Full=Integrator complex subunit 1;
DE            Short=Int1;
GN   Name=INTS1; Synonyms=KIAA1440; ORFNames=UNQ1821/PRO3434;
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
DR   GO; GO:0034474; P:U2 snRNA 3'-end processing; IEA:Ensembl.
//
ID   INT2_HUMAN              Reviewed;        1204 AA.
AC   Q9H0H0; Q9ULD3;
DE   RecName: Full=Integrator complex subunit 2;
DE            Short=Int2;
GN   Name=INTS2; Synonyms=KIAA1287;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT3_HUMAN              Reviewed;        1043 AA.
AC   Q68E01; A8K1W0; B4DQC8; B4E3U9; D3DV57; Q4G0E5; Q5VUQ5; Q5VUQ6;
AC   Q5VUR0; Q5VUR1; Q68DJ1; Q69YR5; Q6AI57; Q6DKG7; Q6MZQ4; Q6MZZ9;
AC   Q8NC46; Q8TB23; Q9H6S9;
DE   RecName: Full=Integrator complex subunit 3;
DE            Short=Int3;
DE   AltName: Full=SOSS complex subunit A;
DE   AltName: Full=Sensor of single-strand DNA complex subunit A;
DE            Short=SOSS-A;
DE            Short=Sensor of ssDNA subunit A;
GN   Name=INTS3; Synonyms=C1orf193, C1orf60;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT4_HUMAN              Reviewed;         963 AA.
AC   Q96HW7; Q2YD62; Q6PJG4; Q7Z4E7; Q96G32; Q96GA1; Q9BRC0;
DE   RecName: Full=Integrator complex subunit 4;
DE            Short=Int4;
GN   Name=INTS4; ORFNames=MSTP093;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT5_HUMAN              Reviewed;        1019 AA.
AC   Q6P9B9; Q8N6W5; Q9C0G5;
DE   RecName: Full=Integrator complex subunit 5;
DE            Short=Int5;
GN   Name=INTS5; Synonyms=KIAA1698;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT6_HUMAN              Reviewed;         887 AA.
AC   Q9UL03; Q0P664; Q6PJP4; Q9UFK0; Q9Y5M9;
DE   RecName: Full=Integrator complex subunit 6;
DE            Short=Int6;
DE   AltName: Full=DBI-1;
DE   AltName: Full=Protein DDX26;
DE   AltName: Full=Protein deleted in cancer 1;
DE            Short=DICE1;
GN   Name=INTS6; Synonyms=DBI1, DDX26, DDX26A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT7_HUMAN              Reviewed;         962 AA.
AC   Q9NVH2; B4DLZ6; B7WNP6; B7WPB6; Q8N4K7; Q8WUH5; Q9H9V3; Q9NVU5;
AC   Q9UFC6; Q9UFM3;
DE   RecName: Full=Integrator complex subunit 7;
DE            Short=Int7;
GN   Name=INTS7; Synonyms=C1orf73;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT8_HUMAN              Reviewed;         995 AA.
AC   Q75QN2; B2RN92; Q5RKZ3; Q6P1R5; Q7Z314; Q9NVS6; Q9NWY7;
DE   RecName: Full=Integrator complex subunit 8;
DE            Short=Int8;
DE   AltName: Full=Protein kaonashi-1;
GN   Name=INTS8; Synonyms=C8orf52;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INT9_HUMAN              Reviewed;         658 AA.
AC   Q9NV88; B7Z560; B7Z6M5; O00224; Q8TB16;
DE   RecName: Full=Integrator complex subunit 9;
DE            Short=Int9;
DE   AltName: Full=Protein related to CPSF subunits of 74 kDa;
DE            Short=RC-74;
GN   Name=INTS9; Synonyms=RC74;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IDA:HGNC.
//
ID   INTU_HUMAN              Reviewed;         942 AA.
AC   Q9ULD6; A1L4N5; D6RAE6; D6RBT4; Q4W5I8; Q86V55;
DE   RecName: Full=Protein inturned;
DE   AltName: Full=Inturned planar cell polarity effector homolog;
DE   AltName: Full=PDZ domain-containing protein 6;
GN   Name=INTU; Synonyms=KIAA1284, PDZD6, PDZK6;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060173; P:limb development; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021513; P:spinal cord dorsal/ventral patterning; IEA:Ensembl.
//
ID   INVO_HUMAN              Reviewed;         585 AA.
AC   P07476; Q5T7P4;
DE   RecName: Full=Involucrin;
GN   Name=IVL;
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0018153; P:isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; TAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
DR   GO; GO:0010224; P:response to UV-B; IDA:UniProtKB.
//
ID   INVS_HUMAN              Reviewed;        1065 AA.
AC   Q9Y283; A2A2Y2; Q2NKL0; Q5W0T6; Q8IVX8; Q9BRB9; Q9Y488; Q9Y498;
DE   RecName: Full=Inversin;
DE   AltName: Full=Inversion of embryo turning homolog;
DE   AltName: Full=Nephrocystin-2;
GN   Name=INVS; Synonyms=INV, NPHP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060971; P:embryonic heart tube left/right pattern formation; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   IOD1_HUMAN              Reviewed;         249 AA.
AC   P49895; Q1RN02; Q3KNP8; Q6Q4C1; Q6Q4C2; Q6Q4C3; Q6Q4C4; Q6Q4C5;
AC   Q6Q4C6; Q6Q4C7; Q6Q4C9; Q8WWC6;
DE   RecName: Full=Type I iodothyronine deiodinase;
DE            EC=1.97.1.10;
DE   AltName: Full=5DI;
DE   AltName: Full=DIOI;
DE   AltName: Full=Type 1 DI;
DE   AltName: Full=Type-I 5'-deiodinase;
GN   Name=DIO1; Synonyms=ITDI1, TXDI1;
DR   GO; GO:0008430; F:selenium binding; TAS:ProtInc.
DR   GO; GO:0004800; F:thyroxine 5'-deiodinase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; TAS:Reactome.
//
ID   IOD2_HUMAN              Reviewed;         273 AA.
AC   Q92813; B9EGK0; G3V315; Q6B0A3; Q9HCP8; Q9P1W4; Q9UDZ1;
DE   RecName: Full=Type II iodothyronine deiodinase;
DE            EC=1.97.1.10;
DE   AltName: Full=5DII;
DE   AltName: Full=DIOII;
DE   AltName: Full=Type 2 DI;
DE   AltName: Full=Type-II 5'-deiodinase;
GN   Name=DIO2; Synonyms=ITDI2, TXDI2;
DR   GO; GO:0008430; F:selenium binding; IC:UniProtKB.
DR   GO; GO:0004800; F:thyroxine 5'-deiodinase activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0001514; P:selenocysteine incorporation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; TAS:UniProtKB.
DR   GO; GO:0042403; P:thyroid hormone metabolic process; IDA:UniProtKB.
//
ID   IOD3_HUMAN              Reviewed;         304 AA.
AC   P55073; G3XAM0; Q8WVN5;
DE   RecName: Full=Type III iodothyronine deiodinase;
DE            EC=1.97.1.11;
DE   AltName: Full=5DIII;
DE   AltName: Full=DIOIII;
DE   AltName: Full=Type 3 DI;
DE   AltName: Full=Type-III 5'-deiodinase;
GN   Name=DIO3; Synonyms=ITDI3, TXDI3;
DR   GO; GO:0004800; F:thyroxine 5'-deiodinase activity; IEA:InterPro.
DR   GO; GO:0033798; F:thyroxine 5-deiodinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; TAS:Reactome.
//
ID   IP3KA_HUMAN             Reviewed;         461 AA.
AC   P23677; Q8TAN3;
DE   RecName: Full=Inositol-trisphosphate 3-kinase A;
DE            EC=2.7.1.127;
DE   AltName: Full=Inositol 1,4,5-trisphosphate 3-kinase A;
DE            Short=IP3 3-kinase A;
DE            Short=IP3K A;
DE            Short=InsP 3-kinase A;
GN   Name=ITPKA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:Ensembl.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0097062; P:dendritic spine maintenance; IEA:Ensembl.
DR   GO; GO:0006020; P:inositol metabolic process; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IP3KC_HUMAN             Reviewed;         683 AA.
AC   Q96DU7; Q9UE25; Q9Y475;
DE   RecName: Full=Inositol-trisphosphate 3-kinase C;
DE            EC=2.7.1.127;
DE   AltName: Full=Inositol 1,4,5-trisphosphate 3-kinase C;
DE            Short=IP3 3-kinase C;
DE            Short=IP3K C;
DE            Short=InsP 3-kinase C;
GN   Name=ITPKC; Synonyms=IP3KC;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IP3KB_HUMAN             Reviewed;         946 AA.
AC   P27987; Q5VWL9; Q5VWM0; Q96BZ2; Q96JS1; Q9UH47;
DE   RecName: Full=Inositol-trisphosphate 3-kinase B;
DE            EC=2.7.1.127;
DE   AltName: Full=Inositol 1,4,5-trisphosphate 3-kinase B;
DE            Short=IP3 3-kinase B;
DE            Short=IP3K B;
DE            Short=InsP 3-kinase B;
GN   Name=ITPKB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IP6K1_HUMAN             Reviewed;         441 AA.
AC   Q92551; A8K157; A8MUX4; Q7L3I7; Q96E38;
DE   RecName: Full=Inositol hexakisphosphate kinase 1;
DE            Short=InsP6 kinase 1;
DE            EC=2.7.4.21;
DE   AltName: Full=Inositol hexaphosphate kinase 1;
GN   Name=IP6K1; Synonyms=IHPK1, KIAA0263;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IP6K2_HUMAN             Reviewed;         426 AA.
AC   Q9UHH9; A8K3B1; B4E3G6; G8JLL6; Q6P0N8; Q9BSZ6; Q9BUW3; Q9H4P7;
AC   Q9NT63; Q9UFU6;
DE   RecName: Full=Inositol hexakisphosphate kinase 2;
DE            Short=InsP6 kinase 2;
DE            EC=2.7.4.21;
DE   AltName: Full=P(i)-uptake stimulator;
DE            Short=PiUS;
GN   Name=IP6K2; Synonyms=IHPK2; ORFNames=TCCCIA00113;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:Ensembl.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IP6K3_HUMAN             Reviewed;         410 AA.
AC   Q96PC2; Q96MQ9;
DE   RecName: Full=Inositol hexakisphosphate kinase 3;
DE            Short=InsP6 kinase 3;
DE            EC=2.7.4.21;
DE   AltName: Full=Inositol hexaphosphate kinase 3;
GN   Name=IP6K3; Synonyms=IHPK3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000831; F:inositol hexakisphosphate 6-kinase activity; IDA:MGI.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
DR   GO; GO:0032958; P:inositol phosphate biosynthetic process; IDA:MGI.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IPIL1_HUMAN             Reviewed;         555 AA.
AC   Q6GPH6; F5H1L8; Q8NE61;
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1;
DE   Flags: Precursor;
GN   Name=ITPRIPL1; Synonyms=KIAA1754L;
//
ID   IPIL2_HUMAN             Reviewed;         535 AA.
AC   Q3MIP1;
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2;
DE   Flags: Precursor;
GN   Name=ITPRIPL2;
//
ID   IPKA_HUMAN              Reviewed;          76 AA.
AC   P61925; P04541; Q6IAV2;
DE   RecName: Full=cAMP-dependent protein kinase inhibitor alpha;
DE            Short=PKI-alpha;
DE   AltName: Full=cAMP-dependent protein kinase inhibitor, muscle/brain isoform;
GN   Name=PKIA; Synonyms=PRKACN1;
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:2000480; P:negative regulation of cAMP-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
//
ID   IPKB_HUMAN              Reviewed;          78 AA.
AC   Q9C010; B2RCK2; Q567T9; Q5T0Z7;
DE   RecName: Full=cAMP-dependent protein kinase inhibitor beta;
DE            Short=PKI-beta;
GN   Name=PKIB; Synonyms=PRKACN2;
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IEA:InterPro.
//
ID   IPKG_HUMAN              Reviewed;          76 AA.
AC   Q9Y2B9;
DE   RecName: Full=cAMP-dependent protein kinase inhibitor gamma;
DE            Short=PKI-gamma;
GN   Name=PKIG;
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; TAS:GOC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
//
ID   IPMK_HUMAN              Reviewed;         416 AA.
AC   Q8NFU5;
DE   RecName: Full=Inositol polyphosphate multikinase;
DE            EC=2.7.1.151;
DE   AltName: Full=Inositol 1,3,4,6-tetrakisphosphate 5-kinase;
GN   Name=IPMK; Synonyms=IMPK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000824; F:inositol tetrakisphosphate 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032958; P:inositol phosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IPO11_HUMAN             Reviewed;         975 AA.
AC   Q9UI26; A6NGJ5; B4DZ73; D3DW98; Q8N5R2; Q9NSJ6; Q9NVB1;
DE   RecName: Full=Importin-11;
DE            Short=Imp11;
DE   AltName: Full=Ran-binding protein 11;
DE            Short=RanBP11;
GN   Name=IPO11; Synonyms=RANBP11;
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0006610; P:ribosomal protein import into nucleus; IEA:Ensembl.
//
ID   IPO13_HUMAN             Reviewed;         963 AA.
AC   O94829; D3DPY4; Q5T4X3; Q7LC04; Q96HS3; Q9H8N3; Q9UFR1;
DE   RecName: Full=Importin-13;
DE            Short=Imp13;
DE   AltName: Full=Karyopherin-13;
DE            Short=Kap13;
DE   AltName: Full=Ran-binding protein 13;
DE            Short=RanBP13;
GN   Name=IPO13; Synonyms=KIAA0724, RANBP13;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:MGI.
//
ID   IPO4_HUMAN              Reviewed;        1081 AA.
AC   Q8TEX9; B2RN95; Q2NL96; Q86TZ9; Q8NCG8; Q96SJ3; Q9BTI4; Q9H5L0;
DE   RecName: Full=Importin-4;
DE            Short=Imp4;
DE   AltName: Full=Importin-4b;
DE            Short=Imp4b;
DE   AltName: Full=Ran-binding protein 4;
DE            Short=RanBP4;
GN   Name=IPO4; Synonyms=IMP4B, RANBP4;
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; NAS:UniProtKB.
//
ID   IPO5_HUMAN              Reviewed;        1097 AA.
AC   O00410; B4DZA0; O15257; Q5T578; Q86XC7;
DE   RecName: Full=Importin-5;
DE            Short=Imp5;
DE   AltName: Full=Importin subunit beta-3;
DE   AltName: Full=Karyopherin beta-3;
DE   AltName: Full=Ran-binding protein 5;
DE            Short=RanBP5;
GN   Name=IPO5; Synonyms=KPNB3, RANBP5;
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; ISS:UniProtKB.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IPO7_HUMAN              Reviewed;        1038 AA.
AC   O95373; A6NNM5; B2R786; Q1RMF7; Q9H177; Q9NTE3;
DE   RecName: Full=Importin-7;
DE            Short=Imp7;
DE   AltName: Full=Ran-binding protein 7;
DE            Short=RanBP7;
GN   Name=IPO7; Synonyms=RANBP7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IPO8_HUMAN              Reviewed;        1037 AA.
AC   O15397; B7Z7M3;
DE   RecName: Full=Importin-8;
DE            Short=Imp8;
DE   AltName: Full=Ran-binding protein 8;
DE            Short=RanBP8;
GN   Name=IPO8; Synonyms=RANBP8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IPO9_HUMAN              Reviewed;        1041 AA.
AC   Q96P70; B1ASV5; Q8N1Y1; Q8N3I2; Q8NCG9; Q96SU6; Q9NW01; Q9P0A8;
AC   Q9ULM8;
DE   RecName: Full=Importin-9;
DE            Short=Imp9;
DE   AltName: Full=Ran-binding protein 9;
DE            Short=RanBP9;
GN   Name=IPO9; Synonyms=IMP9, KIAA1192, RANBP9; ORFNames=HSPC273;
DR   GO; GO:0042393; F:histone binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0006606; P:protein import into nucleus; NAS:UniProtKB.
//
ID   IPP2L_HUMAN             Reviewed;         205 AA.
AC   Q96PQ5;
DE   RecName: Full=Putative protein phosphatase inhibitor 2-like protein 1;
DE   AltName: Full=Protein phosphatase 1, regulatory subunit 2 pseudogene 1;
GN   Name=PPP1R2P1;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   IPP2M_HUMAN             Reviewed;         205 AA.
AC   Q6NXS1;
DE   RecName: Full=Protein phosphatase inhibitor 2-like protein 3;
DE   AltName: Full=Protein phosphatase 1, regulatory subunit 2 pseudogene 3;
GN   Name=PPP1R2P3;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   IPP2_HUMAN              Reviewed;         205 AA.
AC   P41236;
DE   RecName: Full=Protein phosphatase inhibitor 2;
DE            Short=IPP-2;
GN   Name=PPP1R2; Synonyms=IPP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   IPP4_HUMAN              Reviewed;         202 AA.
AC   O14990; Q5H958;
DE   RecName: Full=Putative type-1 protein phosphatase inhibitor 4;
DE            Short=I-4;
DE   AltName: Full=Protein phosphatase 1, regulatory subunit 2 pseudogene 9;
GN   Name=PPP1R2P9;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   IPPK_HUMAN              Reviewed;         491 AA.
AC   Q9H8X2; Q5T9F7; Q9H7V8;
DE   RecName: Full=Inositol-pentakisphosphate 2-kinase;
DE            EC=2.7.1.158;
DE   AltName: Full=IPK1 homolog;
DE   AltName: Full=Inositol-1,3,4,5,6-pentakisphosphate 2-kinase;
DE   AltName: Full=Ins(1,3,4,5,6)P5 2-kinase;
DE            Short=InsP5 2-kinase;
GN   Name=IPPK; Synonyms=C9orf12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035299; F:inositol pentakisphosphate 2-kinase activity; IDA:HGNC.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0052746; P:inositol phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IPP_HUMAN               Reviewed;         584 AA.
AC   Q9Y573; A2A6V4; D3DQ11; Q8N5C3;
DE   RecName: Full=Actin-binding protein IPP;
DE   AltName: Full=Intracisternal A particle-promoted polypeptide;
DE            Short=IPP;
DE   AltName: Full=Kelch-like protein 27;
GN   Name=IPP; Synonyms=KLHL27;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
//
ID   IPRI_HUMAN              Reviewed;         547 AA.
AC   Q8IWB1; D3DRA5; Q5JU17; Q96MS8; Q9C0A9;
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein;
DE   AltName: Full=Protein DANGER;
DE   Flags: Precursor;
GN   Name=ITPRIP; Synonyms=DANGER, KIAA1754;
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:Ensembl.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
//
ID   IPSP_HUMAN              Reviewed;         406 AA.
AC   P05154; Q07616; Q9UG30;
DE   RecName: Full=Plasma serine protease inhibitor;
DE   AltName: Full=Acrosomal serine protease inhibitor;
DE   AltName: Full=Plasminogen activator inhibitor 3;
DE            Short=PAI-3;
DE            Short=PAI3;
DE   AltName: Full=Protein C inhibitor;
DE            Short=PCI;
DE   AltName: Full=Serpin A5;
DE   Flags: Precursor;
GN   Name=SERPINA5; Synonyms=PCI, PLANH3, PROCI;
DR   GO; GO:0032190; F:acrosin binding; IPI:UniProtKB.
DR   GO; GO:0005539; F:glycosaminoglycan binding; TAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; TAS:UniProtKB.
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; NAS:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   IPYR2_HUMAN             Reviewed;         334 AA.
AC   Q9H2U2; B4DLP7; F8WDN9; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55;
AC   Q9H0T0; Q9NX37; Q9P033; Q9ULX0;
DE   RecName: Full=Inorganic pyrophosphatase 2, mitochondrial;
DE            EC=3.6.1.1;
DE   AltName: Full=Pyrophosphatase SID6-306;
DE   AltName: Full=Pyrophosphate phospho-hydrolase 2;
DE            Short=PPase 2;
DE   Flags: Precursor;
GN   Name=PPA2; ORFNames=HSPC124;
DR   GO; GO:0004427; F:inorganic diphosphatase activity; TAS:Reactome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0071344; P:diphosphate metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   IPYR_HUMAN              Reviewed;         289 AA.
AC   Q15181; Q2M348; Q5SQT7; Q6P7P4; Q9UQJ5; Q9Y5B1;
DE   RecName: Full=Inorganic pyrophosphatase;
DE            EC=3.6.1.1;
DE   AltName: Full=Pyrophosphate phospho-hydrolase;
DE            Short=PPase;
GN   Name=PPA1; Synonyms=IOPPP, PP;
DR   GO; GO:0004427; F:inorganic diphosphatase activity; EXP:Reactome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0071344; P:diphosphate metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   IQCA1_HUMAN             Reviewed;         822 AA.
AC   Q86XH1; B4DFH9; E7EWQ0; Q4G164; Q53R37; Q53RV3; Q96NS7; Q9H680;
DE   RecName: Full=IQ and AAA domain-containing protein 1;
GN   Name=IQCA1; Synonyms=IQCA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   IQCAL_HUMAN             Reviewed;         817 AA.
AC   A6NCM1;
DE   RecName: Full=Putative IQ and AAA domain-containing protein 1-like;
DE   AltName: Full=Putative IQ and AAA domain-containing protein 1 pseudogene 1;
GN   Name=IQCA1P1; Synonyms=IQCA1L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   IQCB1_HUMAN             Reviewed;         598 AA.
AC   Q15051; Q3KS08; Q3KS09; Q5DKQ7; Q8NI79; Q9BS08;
DE   RecName: Full=IQ calmodulin-binding motif-containing protein 1;
DE   AltName: Full=Nephrocystin-5;
DE   AltName: Full=p53 and DNA damage-regulated IQ motif protein;
DE            Short=PIQ;
GN   Name=IQCB1; Synonyms=KIAA0036, NPHP5; ORFNames=OK/SW-cl.85;
DR   GO; GO:0005516; F:calmodulin binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0048496; P:maintenance of organ identity; IMP:HGNC.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
//
ID   IQCC_HUMAN              Reviewed;         466 AA.
AC   Q4KMZ1; F5H7T8; Q4KMS3; Q4KMZ5; Q53FL2; Q5TFJ8; Q9NVS3;
DE   RecName: Full=IQ domain-containing protein C;
GN   Name=IQCC;
//
ID   IQCD_HUMAN              Reviewed;         449 AA.
AC   Q96DY2; Q6ZSU0;
DE   RecName: Full=IQ domain-containing protein D;
GN   Name=IQCD;
//
ID   IQCE_HUMAN              Reviewed;         695 AA.
AC   Q6IPM2; Q4G0P7; Q6P7T4; Q9H0H7; Q9UPX7;
DE   RecName: Full=IQ domain-containing protein E;
GN   Name=IQCE; Synonyms=KIAA1023;
//
ID   IQCF2_HUMAN             Reviewed;         164 AA.
AC   Q8IXL9;
DE   RecName: Full=IQ domain-containing protein F2;
GN   Name=IQCF2;
//
ID   IQCF1_HUMAN             Reviewed;         205 AA.
AC   Q8N6M8; Q8N711;
DE   RecName: Full=IQ domain-containing protein F1;
GN   Name=IQCF1;
//
ID   IQCF3_HUMAN             Reviewed;         154 AA.
AC   P0C7M6; B2RUV0;
DE   RecName: Full=IQ domain-containing protein F3;
GN   Name=IQCF3;
//
ID   IQCF5_HUMAN             Reviewed;         148 AA.
AC   A8MTL0;
DE   RecName: Full=IQ domain-containing protein F5;
GN   Name=IQCF5;
//
ID   IQCF6_HUMAN             Reviewed;         107 AA.
AC   A8MYZ5;
DE   RecName: Full=IQ domain-containing protein F6;
GN   Name=IQCF6;
//
ID   IQCH_HUMAN              Reviewed;        1027 AA.
AC   Q86VS3; A8K8W3; C9JPR6; D6RJ88; Q4G0S6; Q8NEH9; Q9BWX2; Q9H9Y1;
AC   Q9UF88;
DE   RecName: Full=IQ domain-containing protein H;
DE   AltName: Full=Testis development protein NYD-SP5;
GN   Name=IQCH;
//
ID   IQCG_HUMAN              Reviewed;         443 AA.
AC   Q9H095; Q9BST2; Q9HAG8;
DE   RecName: Full=IQ domain-containing protein G;
GN   Name=IQCG;
//
ID   IQCK_HUMAN              Reviewed;         287 AA.
AC   Q8N0W5; B2RDU0; O43327; Q8NFF4;
DE   RecName: Full=IQ domain-containing protein K;
GN   Name=IQCK;
//
ID   IQCJ_HUMAN              Reviewed;         159 AA.
AC   Q1A5X6; B7ZMM2; B9EH97; Q1A5X5;
DE   RecName: Full=IQ domain-containing protein J;
GN   Name=IQCJ;
//
ID   IQEC1_HUMAN             Reviewed;         963 AA.
AC   Q6DN90; O94863; Q96D85;
DE   RecName: Full=IQ motif and SEC7 domain-containing protein 1;
DE   AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 100;
DE   AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 2;
DE   AltName: Full=Brefeldin-resistant Arf-GEF 2 protein;
GN   Name=IQSEC1; Synonyms=ARFGEP100, BRAG2, KIAA0763;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   IQEC2_HUMAN             Reviewed;        1478 AA.
AC   Q5JU85; B3KT97; C7SDG1; O60275; Q5JUX1;
DE   RecName: Full=IQ motif and SEC7 domain-containing protein 2;
GN   Name=IQSEC2; Synonyms=KIAA0522;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   IQEC3_HUMAN             Reviewed;        1182 AA.
AC   Q9UPP2; A6NIF2; A6NKV9; Q8TB43;
DE   RecName: Full=IQ motif and SEC7 domain-containing protein 3;
GN   Name=IQSEC3; Synonyms=KIAA1110;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   IQGA1_HUMAN             Reviewed;        1657 AA.
AC   P46940; A7MBM3;
DE   RecName: Full=Ras GTPase-activating-like protein IQGAP1;
DE   AltName: Full=p195;
GN   Name=IQGAP1; Synonyms=KIAA0051;
DR   GO; GO:0005509; F:calcium ion binding; TAS:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; IPI:BHF-UCL.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0035305; P:negative regulation of dephosphorylation; IEA:Ensembl.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0001817; P:regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IQGA2_HUMAN             Reviewed;        1575 AA.
AC   Q13576; A8K4V1; B7Z8A4;
DE   RecName: Full=Ras GTPase-activating-like protein IQGAP2;
GN   Name=IQGAP2;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   IQGA3_HUMAN             Reviewed;        1631 AA.
AC   Q86VI3; Q5T3H8;
DE   RecName: Full=Ras GTPase-activating-like protein IQGAP3;
GN   Name=IQGAP3;
DR   GO; GO:0005099; F:Ras GTPase activator activity; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
//
ID   IQUB_HUMAN              Reviewed;         791 AA.
AC   Q8NA54; A4D0X0; Q49AL6; Q4G189; Q5BJD9; Q6NUH6; Q8N9Y2;
DE   RecName: Full=IQ and ubiquitin-like domain-containing protein;
GN   Name=IQUB;
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
//
ID   IR3IP_HUMAN             Reviewed;          82 AA.
AC   Q9Y5U9;
DE   RecName: Full=Immediate early response 3-interacting protein 1;
GN   Name=IER3IP1; ORFNames=HSPC039;
DR   GO; GO:2000269; P:regulation of fibroblast apoptotic process; IMP:UniProtKB.
//
ID   IRAK1_HUMAN             Reviewed;         712 AA.
AC   P51617; D3DWW3; D3DWW4; Q7Z5V4; Q96C06; Q96RL2;
DE   RecName: Full=Interleukin-1 receptor-associated kinase 1;
DE            Short=IRAK-1;
DE            EC=2.7.11.1;
GN   Name=IRAK1; Synonyms=IRAK;
DR   GuidetoPHARMACOLOGY; 2042; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IDA:MGI.
DR   GO; GO:0004704; F:NF-kappaB-inducing kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:Reactome.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; NAS:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:GOC.
DR   GO; GO:0001959; P:regulation of cytokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0032494; P:response to peptidoglycan; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; NAS:UniProtKB.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   IRAK2_HUMAN             Reviewed;         625 AA.
AC   O43187; B4DQZ6; Q08AG6; Q5K546;
DE   RecName: Full=Interleukin-1 receptor-associated kinase-like 2;
DE            Short=IRAK-2;
GN   Name=IRAK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0001959; P:regulation of cytokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   IRAK3_HUMAN             Reviewed;         596 AA.
AC   Q9Y616; B4DQ57;
DE   RecName: Full=Interleukin-1 receptor-associated kinase 3;
DE            Short=IRAK-3;
DE            EC=2.7.11.1;
DE   AltName: Full=IL-1 receptor-associated kinase M;
DE            Short=IRAK-M;
GN   Name=IRAK3;
DR   GuidetoPHARMACOLOGY; 2044; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0045824; P:negative regulation of innate immune response; ISS:BHF-UCL.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IMP:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IMP:BHF-UCL.
DR   GO; GO:0010936; P:negative regulation of macrophage cytokine production; ISS:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0043242; P:negative regulation of protein complex disassembly; IMP:BHF-UCL.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0010933; P:positive regulation of macrophage tolerance induction; ISS:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043244; P:regulation of protein complex disassembly; ISS:UniProtKB.
DR   GO; GO:0043330; P:response to exogenous dsRNA; ISS:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0032494; P:response to peptidoglycan; ISS:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IC:BHF-UCL.
//
ID   IRAK4_HUMAN             Reviewed;         460 AA.
AC   Q9NWZ3; Q69FE1; Q8TDF7; Q9Y589;
DE   RecName: Full=Interleukin-1 receptor-associated kinase 4;
DE            Short=IRAK-4;
DE            EC=2.7.11.1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-64;
GN   Name=IRAK4;
DR   GuidetoPHARMACOLOGY; 2045; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; EXP:Reactome.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; EXP:Reactome.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   IREB2_HUMAN             Reviewed;         963 AA.
AC   P48200; A8KAC7; Q13095; Q1HE21; Q59FQ7; Q9UF17;
DE   RecName: Full=Iron-responsive element-binding protein 2;
DE            Short=IRE-BP 2;
DE   AltName: Full=Iron regulatory protein 2;
DE            Short=IRP2;
GN   Name=IREB2;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0030350; F:iron-responsive element binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0006826; P:iron ion transport; TAS:UniProtKB.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
DR   GO; GO:0010040; P:response to iron(II) ion; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   IRF1_HUMAN              Reviewed;         325 AA.
AC   P10914; Q96GG7;
DE   RecName: Full=Interferon regulatory factor 1;
DE            Short=IRF-1;
GN   Name=IRF1;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0043374; P:CD8-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IDA:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0045590; P:negative regulation of regulatory T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; ISS:UniProtKB.
DR   GO; GO:0002819; P:regulation of adaptive immune response; TAS:UniProtKB.
DR   GO; GO:2000564; P:regulation of CD8-positive, alpha-beta T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; TAS:UniProtKB.
DR   GO; GO:0034124; P:regulation of MyD88-dependent toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF2_HUMAN              Reviewed;         349 AA.
AC   P14316; D6RCK5; H0Y8S3; Q6IAS7; Q96B99;
DE   RecName: Full=Interferon regulatory factor 2;
DE            Short=IRF-2;
GN   Name=IRF2;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF3_HUMAN              Reviewed;         427 AA.
AC   Q14653; A8K7L2; Q5FBY1; Q5FBY2; Q5FBY4; Q7Z5G6;
DE   RecName: Full=Interferon regulatory factor 3;
DE            Short=IRF-3;
GN   Name=IRF3;
DR   GO; GO:0003677; F:DNA binding; NAS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:UniProtKB.
DR   GO; GO:0071359; P:cellular response to dsRNA; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0071888; P:macrophage apoptotic process; TAS:UniProtKB.
DR   GO; GO:0039530; P:MDA-5 signaling pathway; TAS:UniProtKB.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050689; P:negative regulation of defense response to virus by host; IEA:Ensembl.
DR   GO; GO:0045358; P:negative regulation of interferon-beta biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; ISS:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; ISS:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045351; P:type I interferon biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   IRF4_HUMAN              Reviewed;         451 AA.
AC   Q15306; Q5VUI7; Q99660;
DE   RecName: Full=Interferon regulatory factor 4;
DE            Short=IRF-4;
DE   AltName: Full=Lymphocyte-specific interferon regulatory factor;
DE            Short=LSIRF;
DE   AltName: Full=Multiple myeloma oncogene 1;
DE   AltName: Full=NF-EM5;
GN   Name=IRF4; Synonyms=MUM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:Ensembl.
DR   GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IEA:Ensembl.
DR   GO; GO:0043967; P:histone H4 acetylation; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045082; P:positive regulation of interleukin-10 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045368; P:positive regulation of interleukin-13 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045404; P:positive regulation of interleukin-4 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045622; P:regulation of T-helper cell differentiation; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0072540; P:T-helper 17 cell lineage commitment; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF5_HUMAN              Reviewed;         498 AA.
AC   Q13568; A4D1J8; A8DUA8; A8DUA9; E7EQ16; E7EW54; Q1A7B4; Q64GA9;
AC   Q64GB1; Q64GB2; Q6RCM8; Q9BQF0;
DE   RecName: Full=Interferon regulatory factor 5;
DE            Short=IRF-5;
GN   Name=IRF5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IC:BHF-UCL.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IC:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IDA:BHF-UCL.
DR   GO; GO:0032494; P:response to peptidoglycan; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF6_HUMAN              Reviewed;         467 AA.
AC   O14896; B4DLE2; D3DT90; F5GWX8; G0ZTL0;
DE   RecName: Full=Interferon regulatory factor 6;
DE            Short=IRF-6;
GN   Name=IRF6;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF7_HUMAN              Reviewed;         503 AA.
AC   Q92985; B9EGL3; O00331; O00332; O00333; O75924; Q9UE79;
DE   RecName: Full=Interferon regulatory factor 7;
DE            Short=IRF-7;
GN   Name=IRF7;
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0019043; P:establishment of viral latency; TAS:UniProtKB.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0032607; P:interferon-alpha production; ISS:UniProtKB.
DR   GO; GO:0032608; P:interferon-beta production; ISS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0039530; P:MDA-5 signaling pathway; TAS:UniProtKB.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2000110; P:negative regulation of macrophage apoptotic process; TAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; TAS:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; TAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0002819; P:regulation of adaptive immune response; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:UniProtKB.
DR   GO; GO:0045655; P:regulation of monocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0034124; P:regulation of MyD88-dependent toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034127; P:regulation of MyD88-independent toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045351; P:type I interferon biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF9_HUMAN              Reviewed;         393 AA.
AC   Q00978; D3DS61;
DE   RecName: Full=Interferon regulatory factor 9;
DE            Short=IRF-9;
DE   AltName: Full=IFN-alpha-responsive transcription factor subunit;
DE   AltName: Full=ISGF3 p48 subunit;
DE   AltName: Full=Interferon-stimulated gene factor 3 gamma;
DE            Short=ISGF-3 gamma;
DE   AltName: Full=Transcriptional regulator ISGF3 subunit gamma;
GN   Name=IRF9; Synonyms=ISGF3G;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045351; P:type I interferon biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRF8_HUMAN              Reviewed;         426 AA.
AC   Q02556; A0AV82;
DE   RecName: Full=Interferon regulatory factor 8;
DE            Short=IRF-8;
DE   AltName: Full=Interferon consensus sequence-binding protein;
DE            Short=H-ICSBP;
DE            Short=ICSBP;
GN   Name=IRF8; Synonyms=ICSBP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000975; F:regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030099; P:myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006909; P:phagocytosis; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   IRG1_HUMAN              Reviewed;         481 AA.
AC   A6NK06;
DE   RecName: Full=Cis-aconitate decarboxylase;
DE            Short=CAD;
DE            EC=4.1.1.6;
DE   AltName: Full=Aconitate decarboxylase;
DE   AltName: Full=Cis-aconitic acid decarboxylase;
DE   AltName: Full=Immune-responsive gene 1 protein;
GN   Name=IRG1;
DR   GO; GO:0047547; F:2-methylcitrate dehydratase activity; IEA:InterPro.
DR   GO; GO:0047613; F:aconitate decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0035458; P:cellular response to interferon-beta; ISS:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; ISS:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; ISS:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0071219; P:cellular response to molecule of bacterial origin; ISS:UniProtKB.
DR   GO; GO:0071393; P:cellular response to progesterone stimulus; ISS:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:UniProtKB.
DR   GO; GO:0006952; P:defense response; IDA:UniProtKB.
DR   GO; GO:0007566; P:embryo implantation; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0045824; P:negative regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; ISS:UniProtKB.
DR   GO; GO:0002760; P:positive regulation of antimicrobial humoral response; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.
DR   GO; GO:0019543; P:propionate catabolic process; IEA:InterPro.
DR   GO; GO:0072573; P:tolerance induction to lipopolysaccharide; IDA:UniProtKB.
//
ID   IRGM_HUMAN              Reviewed;         181 AA.
AC   A1A4Y4; B3VEX0;
DE   RecName: Full=Immunity-related GTPase family M protein;
DE            EC=3.6.5.-;
DE   AltName: Full=Immunity-related GTPase family M protein 1;
DE   AltName: Full=Interferon-inducible protein 1;
DE   AltName: Full=LPS-stimulated RAW 264.7 macrophage protein 47 homolog;
DE            Short=LRG-47;
GN   Name=IRGM; Synonyms=IFI1, IRGM1, LRG47;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   IRGQ_HUMAN              Reviewed;         623 AA.
AC   Q8WZA9; B2RNP3;
DE   RecName: Full=Immunity-related GTPase family Q protein;
GN   Name=IRGQ; Synonyms=IRGQ1; ORFNames=FKSG27;
//
ID   IRPL1_HUMAN             Reviewed;         696 AA.
AC   Q9NZN1; A0AVG4; Q9UJ53;
DE   RecName: Full=Interleukin-1 receptor accessory protein-like 1;
DE            Short=IL-1-RAPL-1;
DE            Short=IL-1RAPL-1;
DE            Short=IL1RAPL-1;
DE   AltName: Full=Oligophrenin-4;
DE   AltName: Full=Three immunoglobulin domain-containing IL-1 receptor-related 2;
DE            Short=TIGIRR-2;
DE   AltName: Full=X-linked interleukin-1 receptor accessory protein-like 1;
DE   Flags: Precursor;
GN   Name=IL1RAPL1; Synonyms=OPHN4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; ISS:GOC.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0045920; P:negative regulation of exocytosis; IDA:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   IRPL2_HUMAN             Reviewed;         686 AA.
AC   Q9NP60; Q2M3U3; Q9NZN0;
DE   RecName: Full=X-linked interleukin-1 receptor accessory protein-like 2;
DE            Short=IL-1 receptor accessory protein-like 2;
DE            Short=IL-1-RAPL-2;
DE            Short=IL-1RAPL-2;
DE            Short=IL1RAPL-2;
DE   AltName: Full=IL1RAPL-2-related protein;
DE   AltName: Full=Interleukin-1 receptor 9;
DE            Short=IL-1R-9;
DE            Short=IL-1R9;
DE   AltName: Full=Three immunoglobulin domain-containing IL-1 receptor-related 1;
DE            Short=TIGIRR-1;
DE   Flags: Precursor;
GN   Name=IL1RAPL2; Synonyms=IL1R9;
DR   GO; GO:0004908; F:interleukin-1 receptor activity; TAS:ProtInc.
DR   GO; GO:0004910; F:interleukin-1, Type II, blocking receptor activity; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:GOC.
//
ID   IRS1_HUMAN              Reviewed;        1242 AA.
AC   P35568;
DE   RecName: Full=Insulin receptor substrate 1;
DE            Short=IRS-1;
GN   Name=IRS1;
DR   GO; GO:0005158; F:insulin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:BHF-UCL.
DR   GO; GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0010907; P:positive regulation of glucose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:BHF-UCL.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IDA:BHF-UCL.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IRS2_HUMAN              Reviewed;        1338 AA.
AC   Q9Y4H2; Q96RR2; Q9BZG0; Q9Y6I5;
DE   RecName: Full=Insulin receptor substrate 2;
DE            Short=IRS-2;
GN   Name=IRS2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0055088; P:lipid homeostasis; TAS:BHF-UCL.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0002903; P:negative regulation of B cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0033673; P:negative regulation of kinase activity; ISS:BHF-UCL.
DR   GO; GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:0010907; P:positive regulation of glucose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; TAS:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IRS4_HUMAN              Reviewed;        1257 AA.
AC   O14654;
DE   RecName: Full=Insulin receptor substrate 4;
DE            Short=IRS-4;
DE   AltName: Full=160 kDa phosphotyrosine protein;
DE            Short=py160;
DE   AltName: Full=Phosphoprotein of 160 kDa;
DE            Short=pp160;
GN   Name=IRS4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   IRX1_HUMAN              Reviewed;         480 AA.
AC   P78414; Q7Z2F8; Q8N312;
DE   RecName: Full=Iroquois-class homeodomain protein IRX-1;
DE   AltName: Full=Homeodomain protein IRXA1;
DE   AltName: Full=Iroquois homeobox protein 1;
GN   Name=IRX1; Synonyms=IRXA1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0072272; P:proximal/distal pattern formation involved in metanephric nephron development; IEA:Ensembl.
DR   GO; GO:0072086; P:specification of loop of Henle identity; IEA:Ensembl.
//
ID   IRX2_HUMAN              Reviewed;         471 AA.
AC   Q9BZI1; Q68A19; Q7Z2I7;
DE   RecName: Full=Iroquois-class homeodomain protein IRX-2;
DE   AltName: Full=Homeodomain protein IRXA2;
DE   AltName: Full=Iroquois homeobox protein 2;
GN   Name=IRX2; Synonyms=IRXA2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0072272; P:proximal/distal pattern formation involved in metanephric nephron development; IEA:Ensembl.
DR   GO; GO:0072086; P:specification of loop of Henle identity; IEA:Ensembl.
//
ID   IRX3_HUMAN              Reviewed;         501 AA.
AC   P78415; Q7Z4A4; Q7Z4A5; Q8IVC6;
DE   RecName: Full=Iroquois-class homeodomain protein IRX-3;
DE   AltName: Full=Homeodomain protein IRXB1;
DE   AltName: Full=Iroquois homeobox protein 3;
GN   Name=IRX3; Synonyms=IRXB1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0072086; P:specification of loop of Henle identity; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IRX4_HUMAN              Reviewed;         519 AA.
AC   P78413; B2RMW5; D3DTC5; H1AFL0; H1AFL1; Q2NL64; Q9UHR2;
DE   RecName: Full=Iroquois-class homeodomain protein IRX-4;
DE   AltName: Full=Homeodomain protein IRXA3;
DE   AltName: Full=Iroquois homeobox protein 4;
GN   Name=IRX4; Synonyms=IRXA3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048561; P:establishment of organ orientation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
//
ID   IRX5_HUMAN              Reviewed;         483 AA.
AC   P78411; H0YMS7; P78416; Q7Z2E1;
DE   RecName: Full=Iroquois-class homeodomain protein IRX-5;
DE   AltName: Full=Homeodomain protein IRX-2A;
DE   AltName: Full=Homeodomain protein IRXB2;
DE   AltName: Full=Iroquois homeobox protein 5;
GN   Name=IRX5; Synonyms=IRX2A, IRXB2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0005499; F:vitamin D binding; IEA:UniProtKB-KW.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:UniProtKB.
DR   GO; GO:0008406; P:gonad development; IMP:UniProtKB.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060040; P:retinal bipolar neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   IRX6_HUMAN              Reviewed;         446 AA.
AC   P78412; B2RN06; Q7Z2K0;
DE   RecName: Full=Iroquois-class homeodomain protein IRX-6;
DE   AltName: Full=Homeodomain protein IRXB3;
DE   AltName: Full=Iroquois homeobox protein 6;
GN   Name=IRX6; Synonyms=IRX7, IRXB3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   ISCA1_HUMAN             Reviewed;         129 AA.
AC   Q9BUE6; B3KP34; Q8ND75; Q9BZR2;
DE   RecName: Full=Iron-sulfur cluster assembly 1 homolog, mitochondrial;
DE   AltName: Full=HESB-like domain-containing protein 2;
DE   AltName: Full=Iron-sulfur assembly protein IscA;
DE            Short=hIscA;
DE   Flags: Precursor;
GN   Name=ISCA1; Synonyms=HBLD2; ORFNames=GK004;
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
//
ID   ISCA2_HUMAN             Reviewed;         154 AA.
AC   Q86U28; A6NFF1; A8K3W3; Q8IYZ0; Q96BB2;
DE   RecName: Full=Iron-sulfur cluster assembly 2 homolog, mitochondrial;
DE   AltName: Full=HESB-like domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=ISCA2; Synonyms=HBLD1;
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
//
ID   ISCU_HUMAN              Reviewed;         167 AA.
AC   Q9H1K1; Q6P713; Q99617; Q9H1K2;
DE   RecName: Full=Iron-sulfur cluster assembly enzyme ISCU, mitochondrial;
DE   AltName: Full=NifU-like N-terminal domain-containing protein;
DE   AltName: Full=NifU-like protein;
DE   Flags: Precursor;
GN   Name=ISCU; Synonyms=NIFUN;
DR   GO; GO:0005506; F:iron ion binding; TAS:UniProtKB.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:HGNC.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; TAS:UniProtKB.
DR   GO; GO:0009399; P:nitrogen fixation; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ISG15_HUMAN             Reviewed;         165 AA.
AC   P05161; Q5SVA4; Q7Z2G2; Q96GF0;
DE   RecName: Full=Ubiquitin-like protein ISG15;
DE   AltName: Full=Interferon-induced 15 kDa protein;
DE   AltName: Full=Interferon-induced 17 kDa protein;
DE            Short=IP17;
DE   AltName: Full=Ubiquitin cross-reactive protein;
DE            Short=hUCRP;
DE   Flags: Precursor;
GN   Name=ISG15; Synonyms=G1P2, UCRP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031386; F:protein tag; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; IMP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.
DR   GO; GO:0019941; P:modification-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032649; P:regulation of interferon-gamma production; IMP:UniProtKB.
DR   GO; GO:0034340; P:response to type I interferon; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ISG20_HUMAN             Reviewed;         181 AA.
AC   Q96AZ6; O00441; O00586;
DE   RecName: Full=Interferon-stimulated gene 20 kDa protein;
DE            EC=3.1.13.1;
DE   AltName: Full=Estrogen-regulated transcript 45 protein;
DE   AltName: Full=Promyelocytic leukemia nuclear body-associated protein ISG20;
GN   Name=ISG20; Synonyms=HEM45;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0004527; F:exonuclease activity; IMP:UniProtKB.
DR   GO; GO:0008859; F:exoribonuclease II activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008310; F:single-stranded DNA 3'-5' exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0030619; F:U1 snRNA binding; IDA:UniProtKB.
DR   GO; GO:0030620; F:U2 snRNA binding; IDA:UniProtKB.
DR   GO; GO:0034511; F:U3 snoRNA binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   ISK13_HUMAN             Reviewed;          94 AA.
AC   Q1W4C9; A1A4Y2;
DE   RecName: Full=Serine protease inhibitor Kazal-type 13;
DE   AltName: Full=Hepatitis B virus DNA polymerase transactivated serine protease inhibitor;
DE   AltName: Full=Hespintor;
DE   AltName: Full=Serine protease inhibitor Kazal-type 5-like 3;
DE   Flags: Precursor;
GN   Name=SPINK13; Synonyms=HBVDNAPTP1, SPINK5L3;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:1902225; P:negative regulation of acrosome reaction; ISS:UniProtKB.
//
ID   ISK14_HUMAN             Reviewed;          97 AA.
AC   Q6IE38;
DE   RecName: Full=Serine protease inhibitor Kazal-type 14;
DE   Flags: Precursor;
GN   Name=SPINK14; Synonyms=SPINK5L2;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   ISK1_HUMAN              Reviewed;          79 AA.
AC   P00995;
DE   RecName: Full=Pancreatic secretory trypsin inhibitor;
DE   AltName: Full=Serine protease inhibitor Kazal-type 1;
DE   AltName: Full=Tumor-associated trypsin inhibitor;
DE            Short=TATI;
DE   Flags: Precursor;
GN   Name=SPINK1; Synonyms=PSTI;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0090281; P:negative regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0010751; P:negative regulation of nitric oxide mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:1900004; P:negative regulation of serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0060046; P:regulation of acrosome reaction; IEA:Ensembl.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; IEA:Ensembl.
//
ID   ISK2_HUMAN              Reviewed;          84 AA.
AC   P20155; Q6FGH2;
DE   RecName: Full=Serine protease inhibitor Kazal-type 2;
DE   AltName: Full=Acrosin-trypsin inhibitor;
DE   AltName: Full=Epididymis tissue protein Li 172;
DE   AltName: Full=HUSI-II;
DE   Flags: Precursor;
GN   Name=SPINK2;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0002176; P:male germ cell proliferation; IEA:Ensembl.
DR   GO; GO:1900004; P:negative regulation of serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0072520; P:seminiferous tubule development; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   ISK4_HUMAN              Reviewed;          86 AA.
AC   O60575; Q2YDT7;
DE   RecName: Full=Serine protease inhibitor Kazal-type 4;
DE   AltName: Full=Peptide PEC-60 homolog;
DE   Flags: Precursor;
GN   Name=SPINK4;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   ISK5_HUMAN              Reviewed;        1064 AA.
AC   Q9NQ38; A8MYE8; B7WPB7; D6REN5; O75770; Q3LX95; Q3LX96; Q3LX97;
AC   Q96PP2; Q96PP3;
DE   RecName: Full=Serine protease inhibitor Kazal-type 5;
DE   AltName: Full=Lympho-epithelial Kazal-type-related inhibitor;
DE            Short=LEKTI;
DE   Contains:
DE     RecName: Full=Hemofiltrate peptide HF6478;
DE   Contains:
DE     RecName: Full=Hemofiltrate peptide HF7665;
DE   Flags: Precursor;
GN   Name=SPINK5;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0042640; P:anagen; TAS:UniProtKB.
DR   GO; GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; TAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:UniProtKB.
DR   GO; GO:0035315; P:hair cell differentiation; TAS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; TAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0045580; P:regulation of T cell differentiation; TAS:UniProtKB.
//
ID   ISK6_HUMAN              Reviewed;          80 AA.
AC   Q6UWN8; E0X656; Q8N5P0;
DE   RecName: Full=Serine protease inhibitor Kazal-type 6;
DE   AltName: Full=Kallikrein inhibitor;
DE   Flags: Precursor;
GN   Name=SPINK6; ORFNames=UNQ844/PRO1782;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   ISK8_HUMAN              Reviewed;          97 AA.
AC   P0C7L1;
DE   RecName: Full=Serine protease inhibitor Kazal-type 8;
DE   Flags: Precursor;
GN   Name=SPINK8;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   ISK7_HUMAN              Reviewed;          85 AA.
AC   P58062; Q32LY0;
DE   RecName: Full=Serine protease inhibitor Kazal-type 7;
DE   AltName: Full=Esophagus cancer-related gene 2 protein;
DE            Short=ECRG-2;
DE   Flags: Precursor;
GN   Name=SPINK7; Synonyms=ECG2; ORFNames=UNQ745/PRO1474;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   ISK9_HUMAN              Reviewed;          86 AA.
AC   Q5DT21; B2RPN9;
DE   RecName: Full=Serine protease inhibitor Kazal-type 9;
DE   AltName: Full=Lymphoepithelial Kazal-type-related inhibitor 2;
DE   Flags: Precursor;
GN   Name=SPINK9; Synonyms=LEKTI2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
//
ID   ISL2_HUMAN              Reviewed;         359 AA.
AC   Q96A47; B3KM37;
DE   RecName: Full=Insulin gene enhancer protein ISL-2;
DE            Short=Islet-2;
GN   Name=ISL2;
DR   GO; GO:0003677; F:DNA binding; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; TAS:BHF-UCL.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0021524; P:visceral motor neuron differentiation; IEA:Ensembl.
//
ID   ISLR2_HUMAN             Reviewed;         745 AA.
AC   Q6UXK2; A8K352; Q9P263;
DE   RecName: Full=Immunoglobulin superfamily containing leucine-rich repeat protein 2;
DE   AltName: Full=Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein;
DE   Flags: Precursor;
GN   Name=ISLR2; Synonyms=KIAA1465, LINX; ORFNames=UNQ1885/PRO4329;
DR   GO; GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
//
ID   ISL1_HUMAN              Reviewed;         349 AA.
AC   P61371; P20663; P47894;
DE   RecName: Full=Insulin gene enhancer protein ISL-1;
DE            Short=Islet-1;
GN   Name=ISL1;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0030331; F:estrogen receptor binding; ISS:BHF-UCL.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060413; P:atrial septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0060913; P:cardiac cell fate determination; IDA:BHF-UCL.
DR   GO; GO:0060379; P:cardiac muscle cell myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:BHF-UCL.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060384; P:innervation; ISS:BHF-UCL.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0090074; P:negative regulation of protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; ISS:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0031016; P:pancreas development; ISS:BHF-UCL.
DR   GO; GO:0048936; P:peripheral nervous system neuron axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0071657; P:positive regulation of granulocyte colony-stimulating factor production; ISS:BHF-UCL.
DR   GO; GO:0032725; P:positive regulation of granulocyte macrophage colony-stimulating factor production; ISS:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IC:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0032730; P:positive regulation of interleukin-1 alpha production; ISS:BHF-UCL.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; ISS:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; ISS:BHF-UCL.
DR   GO; GO:1901258; P:positive regulation of macrophage colony-stimulating factor production; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:BHF-UCL.
DR   GO; GO:0003266; P:regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0003139; P:secondary heart field specification; IMP:BHF-UCL.
DR   GO; GO:0048880; P:sensory system development; ISS:BHF-UCL.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0021559; P:trigeminal nerve development; ISS:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0021524; P:visceral motor neuron differentiation; IEA:Ensembl.
//
ID   ISLR_HUMAN              Reviewed;         428 AA.
AC   O14498;
DE   RecName: Full=Immunoglobulin superfamily containing leucine-rich repeat protein;
DE   Flags: Precursor;
GN   Name=ISLR; ORFNames=UNQ189/PRO215;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
//
ID   ISM1_HUMAN              Reviewed;         464 AA.
AC   B1AKI9; Q8WVH9;
DE   RecName: Full=Isthmin-1;
DE   Flags: Precursor;
GN   Name=ISM1; Synonyms=C20orf82, ISM;
//
ID   ISM2_HUMAN              Reviewed;         571 AA.
AC   Q6H9L7; A8K6D5; O95432; Q495U5; Q68CN3; Q86TQ7; Q86TW3; Q86TW4;
AC   Q8N501; Q8NBL0;
DE   RecName: Full=Isthmin-2;
DE   AltName: Full=Thrombospondin and AMOP domain-containing isthmin-like protein 1;
DE   AltName: Full=Thrombospondin type-1 domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=ISM2; Synonyms=TAIL1, THSD3; ORFNames=PSEC0137;
//
ID   ISOC1_HUMAN             Reviewed;         298 AA.
AC   Q96CN7; Q7Z770;
DE   RecName: Full=Isochorismatase domain-containing protein 1;
GN   Name=ISOC1; ORFNames=CGI-111;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   ISOC2_HUMAN             Reviewed;         205 AA.
AC   Q96AB3; Q6ZN91; Q9H5G0;
DE   RecName: Full=Isochorismatase domain-containing protein 2, mitochondrial;
DE   Flags: Precursor;
GN   Name=ISOC2;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0031648; P:protein destabilization; IMP:BHF-UCL.
//
ID   ISPD_HUMAN              Reviewed;         451 AA.
AC   A4D126; A8MU35; H9KVB2;
DE   RecName: Full=Isoprenoid synthase domain-containing protein;
DE            EC=2.7.7.-;
DE   AltName: Full=2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein;
GN   Name=ISPD;
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   GO; GO:0035269; P:protein O-linked mannosylation; IMP:UniProtKB.
//
ID   IST1_HUMAN              Reviewed;         364 AA.
AC   P53990; A8KAH5; Q3SYM4; Q9BQ81; Q9BWN2;
DE   RecName: Full=IST1 homolog;
DE            Short=hIST1;
DE   AltName: Full=Putative MAPK-activating protein PM28;
GN   Name=IST1; Synonyms=KIAA0174;
DR   GO; GO:0090541; F:MIT domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0009838; P:abscission; IDA:UniProtKB.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:UniProt.
DR   GO; GO:0048672; P:positive regulation of collateral sprouting; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:0046745; P:viral capsid secondary envelopment; IDA:UniProtKB.
DR   GO; GO:0019076; P:viral release from host cell; IDA:UniProtKB.
//
ID   ISX_HUMAN               Reviewed;         245 AA.
AC   Q2M1V0; Q68DJ5;
DE   RecName: Full=Intestine-specific homeobox;
DE   AltName: Full=RAX-like homeobox;
GN   Name=ISX; Synonyms=RAXLX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:1901738; P:regulation of vitamin A metabolic process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ISY1_HUMAN              Reviewed;         285 AA.
AC   Q9ULR0; Q96IL2; Q9BT05;
DE   RecName: Full=Pre-mRNA-splicing factor ISY1 homolog;
GN   Name=ISY1; Synonyms=KIAA1160;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   ITA10_HUMAN             Reviewed;        1167 AA.
AC   O75578; B2RAM4; B2RTV5; Q6UXJ6; Q9UHZ8;
DE   RecName: Full=Integrin alpha-10;
DE   Flags: Precursor;
GN   Name=ITGA10; ORFNames=UNQ468/PRO827;
DR   GO; GO:0005518; F:collagen binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
//
ID   ITA11_HUMAN             Reviewed;        1188 AA.
AC   Q9UKX5; J3KQM2; Q8WYI8; Q9UKQ1;
DE   RecName: Full=Integrin alpha-11;
DE   Flags: Precursor;
GN   Name=ITGA11; ORFNames=MSTP018;
DR   GO; GO:0005518; F:collagen binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   ITA1_HUMAN              Reviewed;        1179 AA.
AC   P56199; B2RNU0;
DE   RecName: Full=Integrin alpha-1;
DE   AltName: Full=CD49 antigen-like family member A;
DE   AltName: Full=Laminin and collagen receptor;
DE   AltName: Full=VLA-1;
DE   AltName: CD_antigen=CD49a;
DE   Flags: Precursor;
GN   Name=ITGA1;
DR   GO; GO:0005518; F:collagen binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0045123; P:cellular extravasation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   ITA2B_HUMAN             Reviewed;        1039 AA.
AC   P08514; B2RCY8; O95366; Q14443; Q17R67;
DE   RecName: Full=Integrin alpha-IIb;
DE   AltName: Full=GPalpha IIb;
DE            Short=GPIIb;
DE   AltName: Full=Platelet membrane glycoprotein IIb;
DE   AltName: CD_antigen=CD41;
DE   Contains:
DE     RecName: Full=Integrin alpha-IIb heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-IIb light chain, form 1;
DE   Contains:
DE     RecName: Full=Integrin alpha-IIb light chain, form 2;
DE   Flags: Precursor;
GN   Name=ITGA2B; Synonyms=GP2B, ITGAB;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
//
ID   ITA2_HUMAN              Reviewed;        1181 AA.
AC   P17301; Q14595;
DE   RecName: Full=Integrin alpha-2;
DE   AltName: Full=CD49 antigen-like family member B;
DE   AltName: Full=Collagen receptor;
DE   AltName: Full=Platelet membrane glycoprotein Ia;
DE            Short=GPIa;
DE   AltName: Full=VLA-2 subunit alpha;
DE   AltName: CD_antigen=CD49b;
DE   Flags: Precursor;
GN   Name=ITGA2; Synonyms=CD49B;
DR   GO; GO:0005518; F:collagen binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006971; P:hypotonic response; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; IEA:Ensembl.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0031346; P:positive regulation of cell projection organization; IEA:Ensembl.
DR   GO; GO:0033343; P:positive regulation of collagen binding; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0060100; P:positive regulation of phagocytosis, engulfment; IEA:Ensembl.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0051971; P:positive regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0033591; P:response to L-ascorbic acid; IEA:Ensembl.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0043589; P:skin morphogenesis; IEA:Ensembl.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ITA3_HUMAN              Reviewed;        1051 AA.
AC   P26006; A7E246; B7ZM80; B9EGQ1; D3DTX4; D3DTX5;
DE   RecName: Full=Integrin alpha-3;
DE   AltName: Full=CD49 antigen-like family member C;
DE   AltName: Full=FRP-2;
DE   AltName: Full=Galactoprotein B3;
DE            Short=GAPB3;
DE   AltName: Full=VLA-3 subunit alpha;
DE   AltName: CD_antigen=CD49c;
DE   Contains:
DE     RecName: Full=Integrin alpha-3 heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-3 light chain;
DE   Flags: Precursor;
GN   Name=ITGA3; Synonyms=MSK18;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0031345; P:negative regulation of cell projection organization; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0034698; P:response to gonadotropin; IEA:Ensembl.
//
ID   ITA4_HUMAN              Reviewed;        1032 AA.
AC   P13612; D3DPG4;
DE   RecName: Full=Integrin alpha-4;
DE   AltName: Full=CD49 antigen-like family member D;
DE   AltName: Full=Integrin alpha-IV;
DE   AltName: Full=VLA-4 subunit alpha;
DE   AltName: CD_antigen=CD49d;
DE   Flags: Precursor;
GN   Name=ITGA4; Synonyms=CD49D;
DR   GuidetoPHARMACOLOGY; 2443; -.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IC:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0060710; P:chorio-allantoic fusion; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060324; P:face development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0090074; P:negative regulation of protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   ITA5_HUMAN              Reviewed;        1049 AA.
AC   P08648; Q96HA5;
DE   RecName: Full=Integrin alpha-5;
DE   AltName: Full=CD49 antigen-like family member E;
DE   AltName: Full=Fibronectin receptor subunit alpha;
DE   AltName: Full=Integrin alpha-F;
DE   AltName: Full=VLA-5;
DE   AltName: CD_antigen=CD49e;
DE   Contains:
DE     RecName: Full=Integrin alpha-5 heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-5 light chain;
DE   Flags: Precursor;
GN   Name=ITGA5; Synonyms=FNRA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043184; F:vascular endothelial growth factor receptor 2 binding; TAS:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0033631; P:cell-cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0007044; P:cell-substrate junction assembly; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IEP:BHF-UCL.
//
ID   ITA6_HUMAN              Reviewed;        1130 AA.
AC   P23229; B2RMU9; B4DG69; B4DKB8; C4AM96; G5E9H1; Q08443; Q0MRC7;
AC   Q14646; Q16508; Q53RX7; Q59HB7; Q86VL6; Q9UCT1; Q9UN03;
DE   RecName: Full=Integrin alpha-6;
DE   AltName: Full=CD49 antigen-like family member F;
DE   AltName: Full=VLA-6;
DE   AltName: CD_antigen=CD49f;
DE   Contains:
DE     RecName: Full=Integrin alpha-6 heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-6 light chain;
DE   Contains:
DE     RecName: Full=Processed integrin alpha-6;
DE              Short=Alpha6p;
DE   Flags: Precursor;
GN   Name=ITGA6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0007044; P:cell-substrate junction assembly; TAS:ProtInc.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0046847; P:filopodium assembly; IEA:Ensembl.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
//
ID   ITA7_HUMAN              Reviewed;        1181 AA.
AC   Q13683; B4E3U0; C9JMD3; C9JMZ6; O43197; Q86W93; Q9NY89; Q9UET0;
AC   Q9UEV2;
DE   RecName: Full=Integrin alpha-7;
DE   Contains:
DE     RecName: Full=Integrin alpha-7 heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-7 light chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-7 70 kDa form;
DE   Flags: Precursor;
GN   Name=ITGA7; ORFNames=UNQ406/PRO768;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
//
ID   ITA8_HUMAN              Reviewed;        1063 AA.
AC   P53708; B0YJ31; Q5VX94;
DE   RecName: Full=Integrin alpha-8;
DE   Contains:
DE     RecName: Full=Integrin alpha-8 heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-8 light chain;
DE   Flags: Precursor;
GN   Name=ITGA8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030030; P:cell projection organization; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:2000721; P:positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
//
ID   ITA9_HUMAN              Reviewed;        1035 AA.
AC   Q13797; Q14638;
DE   RecName: Full=Integrin alpha-9;
DE   AltName: Full=Integrin alpha-RLC;
DE   Flags: Precursor;
GN   Name=ITGA9;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IGI:MGI.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   ITAD_HUMAN              Reviewed;        1161 AA.
AC   Q13349; Q15575; Q15576;
DE   RecName: Full=Integrin alpha-D;
DE   AltName: Full=ADB2;
DE   AltName: Full=CD11 antigen-like family member D;
DE   AltName: Full=Leukointegrin alpha D;
DE   AltName: CD_antigen=CD11d;
DE   Flags: Precursor;
GN   Name=ITGAD;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050798; P:activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
//
ID   ITAE_HUMAN              Reviewed;        1179 AA.
AC   P38570; Q17RS6; Q9NZU9;
DE   RecName: Full=Integrin alpha-E;
DE   AltName: Full=HML-1 antigen;
DE   AltName: Full=Integrin alpha-IEL;
DE   AltName: Full=Mucosal lymphocyte 1 antigen;
DE   AltName: CD_antigen=CD103;
DE   Contains:
DE     RecName: Full=Integrin alpha-E light chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-E heavy chain;
DE   Flags: Precursor;
GN   Name=ITGAE;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
//
ID   ITAL_HUMAN              Reviewed;        1170 AA.
AC   P20701; O43746; Q45H73; Q96HB1; Q9UBC8;
DE   RecName: Full=Integrin alpha-L;
DE   AltName: Full=CD11 antigen-like family member A;
DE   AltName: Full=Leukocyte adhesion glycoprotein LFA-1 alpha chain;
DE            Short=LFA-1A;
DE   AltName: Full=Leukocyte function-associated molecule 1 alpha chain;
DE   AltName: CD_antigen=CD11a;
DE   Flags: Precursor;
GN   Name=ITGAL; Synonyms=CD11A;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050798; P:activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0002291; P:T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IMP:BHF-UCL.
//
ID   ITAM_HUMAN              Reviewed;        1152 AA.
AC   P11215; Q4VAK0; Q4VAK1; Q4VAK2;
DE   RecName: Full=Integrin alpha-M;
DE   AltName: Full=CD11 antigen-like family member B;
DE   AltName: Full=CR-3 alpha chain;
DE   AltName: Full=Cell surface glycoprotein MAC-1 subunit alpha;
DE   AltName: Full=Leukocyte adhesion receptor MO1;
DE   AltName: Full=Neutrophil adherence receptor;
DE   AltName: CD_antigen=CD11b;
DE   Flags: Precursor;
GN   Name=ITGAM; Synonyms=CD11B, CR3A;
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050798; P:activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0045123; P:cellular extravasation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0014005; P:microglia development; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   ITAV_HUMAN              Reviewed;        1048 AA.
AC   P06756; A0AV67; B0LPF4; B7Z883; B7ZLX0; D3DPG8; E7EWZ6; Q53SK4;
AC   Q59EB7; Q6LD15;
DE   RecName: Full=Integrin alpha-V;
DE   AltName: Full=Vitronectin receptor subunit alpha;
DE   AltName: CD_antigen=CD51;
DE   Contains:
DE     RecName: Full=Integrin alpha-V heavy chain;
DE   Contains:
DE     RecName: Full=Integrin alpha-V light chain;
DE   Flags: Precursor;
GN   Name=ITGAV; Synonyms=MSK8, VNRA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050431; F:transforming growth factor beta binding; ISS:BHF-UCL.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0052066; P:entry of symbiont into host cell by promotion of host phagocytosis; NAS:BHF-UCL.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; ISS:BHF-UCL.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:2000536; P:negative regulation of entry of bacterium into host cell; IDA:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.
DR   GO; GO:0032369; P:negative regulation of lipid transport; IMP:BHF-UCL.
DR   GO; GO:0050748; P:negative regulation of lipoprotein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045715; P:negative regulation of low-density lipoprotein particle receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:2000425; P:regulation of apoptotic cell clearance; ISS:BHF-UCL.
DR   GO; GO:0050764; P:regulation of phagocytosis; IDA:BHF-UCL.
DR   GO; GO:0046718; P:viral entry into host cell; TAS:BHF-UCL.
//
ID   ITAX_HUMAN              Reviewed;        1163 AA.
AC   P20702; Q8IVA6;
DE   RecName: Full=Integrin alpha-X;
DE   AltName: Full=CD11 antigen-like family member C;
DE   AltName: Full=Leu M5;
DE   AltName: Full=Leukocyte adhesion glycoprotein p150,95 alpha chain;
DE   AltName: Full=Leukocyte adhesion receptor p150,95;
DE   AltName: CD_antigen=CD11c;
DE   Flags: Precursor;
GN   Name=ITGAX; Synonyms=CD11C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
//
ID   ITB1_HUMAN              Reviewed;         798 AA.
AC   P05556; A8K6N2; D3DRX9; D3DRY3; D3DRY4; D3DRY5; P78466; P78467;
AC   Q13089; Q13090; Q13091; Q13212; Q14622; Q14647; Q29RW2; Q7Z3V1;
AC   Q8WUM6;
DE   RecName: Full=Integrin beta-1;
DE   AltName: Full=Fibronectin receptor subunit beta;
DE   AltName: Full=Glycoprotein IIa;
DE            Short=GPIIA;
DE   AltName: Full=VLA-4 subunit beta;
DE   AltName: CD_antigen=CD29;
DE   Flags: Precursor;
GN   Name=ITGB1; Synonyms=FNRB, MDF2, MSK12;
DR   GO; GO:0003779; F:actin binding; IDA:BHF-UCL.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030183; P:B cell differentiation; IC:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007161; P:calcium-independent cell-matrix adhesion; IGI:MGI.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; TAS:HGNC.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0033631; P:cell-cell adhesion mediated by integrin; IEP:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0071305; P:cellular response to vitamin D; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0021943; P:formation of radial glial scaffolds; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0031345; P:negative regulation of cell projection organization; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032594; P:protein transport within lipid bilayer; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0034698; P:response to gonadotropin; IEA:Ensembl.
DR   GO; GO:0071559; P:response to transforming growth factor beta; IEA:Ensembl.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IEA:Ensembl.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ITB2_HUMAN              Reviewed;         769 AA.
AC   P05107; B3KTS8; D3DSM1; Q16418; Q53HS5; Q9UD72;
DE   RecName: Full=Integrin beta-2;
DE   AltName: Full=Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;
DE   AltName: Full=Complement receptor C3 subunit beta;
DE   AltName: CD_antigen=CD18;
DE   Flags: Precursor;
GN   Name=ITGB2; Synonyms=CD18, MFI7;
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   ITB3_HUMAN              Reviewed;         788 AA.
AC   P05106; A0PJW2; D3DXJ8; O15495; Q12806; Q13413; Q14648; Q16499;
DE   RecName: Full=Integrin beta-3;
DE   AltName: Full=Platelet membrane glycoprotein IIIa;
DE            Short=GPIIIa;
DE   AltName: CD_antigen=CD61;
DE   Flags: Precursor;
GN   Name=ITGB3; Synonyms=GP3A;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0043184; F:vascular endothelial growth factor receptor 2 binding; IPI:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0060055; P:angiogenesis involved in wound healing; TAS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0007044; P:cell-substrate junction assembly; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.
DR   GO; GO:0032369; P:negative regulation of lipid transport; IMP:BHF-UCL.
DR   GO; GO:0050748; P:negative regulation of lipoprotein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045715; P:negative regulation of low-density lipoprotein particle receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; IMP:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; IMP:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; TAS:BHF-UCL.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; IDA:GOC.
DR   GO; GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.
DR   GO; GO:0014909; P:smooth muscle cell migration; IMP:BHF-UCL.
DR   GO; GO:0035295; P:tube development; TAS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; IC:BHF-UCL.
//
ID   ITB4_HUMAN              Reviewed;        1822 AA.
AC   P16144; A0AVL6; O14690; O14691; O15339; O15340; O15341; Q0VF97;
AC   Q9UIQ4;
DE   RecName: Full=Integrin beta-4;
DE   AltName: Full=GP150;
DE   AltName: CD_antigen=CD104;
DE   Flags: Precursor;
GN   Name=ITGB4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0048870; P:cell motility; IMP:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0046847; P:filopodium assembly; IEA:Ensembl.
DR   GO; GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0009611; P:response to wounding; IDA:UniProtKB.
//
ID   ITB5_HUMAN              Reviewed;         799 AA.
AC   P18084; B0LPF8; B2RD70;
DE   RecName: Full=Integrin beta-5;
DE   Flags: Precursor;
GN   Name=ITGB5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
//
ID   ITB6_HUMAN              Reviewed;         788 AA.
AC   P18564; B2R9W5; Q0VA95; Q16500; Q53RG5; Q53RR6;
DE   RecName: Full=Integrin beta-6;
DE   Flags: Precursor;
GN   Name=ITGB6;
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ITB7_HUMAN              Reviewed;         798 AA.
AC   P26010; Q9UCP7; Q9UCS7;
DE   RecName: Full=Integrin beta-7;
DE   AltName: Full=Gut homing receptor beta subunit;
DE   Flags: Precursor;
GN   Name=ITGB7;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   ITB8_HUMAN              Reviewed;         769 AA.
AC   P26012; A4D133;
DE   RecName: Full=Integrin beta-8;
DE   Flags: Precursor;
GN   Name=ITGB8;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001573; P:ganglioside metabolic process; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0060674; P:placenta blood vessel development; TAS:BHF-UCL.
//
ID   ITBP1_HUMAN             Reviewed;         200 AA.
AC   O14713; D6W4Y9; O14714; Q53RS0;
DE   RecName: Full=Integrin beta-1-binding protein 1;
DE   AltName: Full=Integrin cytoplasmic domain-associated protein 1;
DE            Short=ICAP-1;
GN   Name=ITGB1BP1; Synonyms=ICAP1;
DR   GO; GO:0005092; F:GDP-dissociation inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:UniProtKB.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; TAS:HGNC.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0033622; P:integrin activation; ISS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0051451; P:myoblast migration; ISS:UniProtKB.
DR   GO; GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; ISS:UniProtKB.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0010764; P:negative regulation of fibroblast migration; ISS:UniProtKB.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0090315; P:negative regulation of protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0043113; P:receptor clustering; ISS:UniProtKB.
DR   GO; GO:0050880; P:regulation of blood vessel size; IDA:UniProtKB.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.
DR   GO; GO:2001044; P:regulation of integrin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035148; P:tube formation; IDA:UniProtKB.
//
ID   ITBP2_HUMAN             Reviewed;         347 AA.
AC   Q9UKP3; Q549J7;
DE   RecName: Full=Integrin beta-1-binding protein 2;
DE   AltName: Full=Melusin;
GN   Name=ITGB1BP2; ORFNames=MSTP015;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ITCH_HUMAN              Reviewed;         903 AA.
AC   Q96J02; A6NEW4; B4E234; E1P5P3; F5H217; O43584; Q5QP37; Q5TEL0;
AC   Q96F66; Q9BY75; Q9H451; Q9H4U5;
DE   RecName: Full=E3 ubiquitin-protein ligase Itchy homolog;
DE            Short=Itch;
DE            EC=6.3.2.-;
DE   AltName: Full=Atrophin-1-interacting protein 4;
DE            Short=AIP4;
DE   AltName: Full=NFE2-associated polypeptide 1;
DE            Short=NAPP1;
GN   Name=ITCH;
DR   GO; GO:0045236; F:CXCR chemokine receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; ISS:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0002669; P:positive regulation of T cell anergy; IEA:Ensembl.
DR   GO; GO:0035519; P:protein K29-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0090085; P:regulation of protein deubiquitination; ISS:BHF-UCL.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
//
ID   ITF2_HUMAN              Reviewed;         667 AA.
AC   P15884; B3KT62; B3KUC0; B4DT37; B4DUG3; B7Z5M6; B7Z6Y1; G0LNT9;
AC   G0LNU0; G0LNU1; G0LNU2; G0LNU4; G0LNU5; G0LNU8; G0LNU9; G0LNV0;
AC   G0LNV1; G0LNV2; H3BPQ1; Q08AP2; Q08AP3; Q15439; Q15440; Q15441;
DE   RecName: Full=Transcription factor 4;
DE            Short=TCF-4;
DE   AltName: Full=Class B basic helix-loop-helix protein 19;
DE            Short=bHLHb19;
DE   AltName: Full=Immunoglobulin transcription factor 2;
DE            Short=ITF-2;
DE   AltName: Full=SL3-3 enhancer factor 2;
DE            Short=SEF-2;
GN   Name=TCF4; Synonyms=BHLHB19, ITF2, SEF2;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0001011; F:sequence-specific DNA binding RNA polymerase recruiting transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0001087; F:TFIIB-class binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001093; F:TFIIB-class transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; ISS:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0065004; P:protein-DNA complex assembly; ISS:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   ITFG2_HUMAN             Reviewed;         447 AA.
AC   Q969R8; A8K4Z5; D3DUQ2; Q96SX6;
DE   RecName: Full=Integrin-alpha FG-GAP repeat-containing protein 2;
GN   Name=ITFG2;
//
ID   ITFG3_HUMAN             Reviewed;         552 AA.
AC   Q9H0X4; D3DU45; Q7L416; Q96FR1; Q96MC7; Q96S30;
DE   RecName: Full=Protein ITFG3;
GN   Name=ITFG3; Synonyms=C16orf9;
//
ID   ITGBL_HUMAN             Reviewed;         494 AA.
AC   O95965; A8K5M5; B3KTP1; B4DQ02; Q8N172; Q9NPR0;
DE   RecName: Full=Integrin beta-like protein 1;
DE   AltName: Full=Osteoblast-specific cysteine-rich protein;
DE   AltName: Full=Ten integrin EGF-like repeat domain-containing protein;
DE   Flags: Precursor;
GN   Name=ITGBL1; Synonyms=OSCP, TIED;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
//
ID   ITIH1_HUMAN             Reviewed;         911 AA.
AC   P19827; A8K9N5; B2RAH9; B7Z558; B7Z8C0; F5H165; F5H7Y8; P78455;
AC   Q01746; Q562G1;
DE   RecName: Full=Inter-alpha-trypsin inhibitor heavy chain H1;
DE            Short=ITI heavy chain H1;
DE            Short=ITI-HC1;
DE            Short=Inter-alpha-inhibitor heavy chain 1;
DE   AltName: Full=Inter-alpha-trypsin inhibitor complex component III;
DE   AltName: Full=Serum-derived hyaluronan-associated protein;
DE            Short=SHAP;
DE   Flags: Precursor;
GN   Name=ITIH1; Synonyms=IGHEP1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:InterPro.
//
ID   ITIH2_HUMAN             Reviewed;         946 AA.
AC   P19823; Q14659; Q15484; Q5T986;
DE   RecName: Full=Inter-alpha-trypsin inhibitor heavy chain H2;
DE            Short=ITI heavy chain H2;
DE            Short=ITI-HC2;
DE            Short=Inter-alpha-inhibitor heavy chain 2;
DE   AltName: Full=Inter-alpha-trypsin inhibitor complex component II;
DE   AltName: Full=Serum-derived hyaluronan-associated protein;
DE            Short=SHAP;
DE   Flags: Precursor;
GN   Name=ITIH2; Synonyms=IGHEP2;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:InterPro.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   ITIH3_HUMAN             Reviewed;         890 AA.
AC   Q06033; Q3B7H5; Q53F06; Q6LAM2; Q99085;
DE   RecName: Full=Inter-alpha-trypsin inhibitor heavy chain H3;
DE            Short=ITI heavy chain H3;
DE            Short=ITI-HC3;
DE            Short=Inter-alpha-inhibitor heavy chain 3;
DE   AltName: Full=Serum-derived hyaluronan-associated protein;
DE            Short=SHAP;
DE   Flags: Precursor;
GN   Name=ITIH3;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:InterPro.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   ITIH4_HUMAN             Reviewed;         930 AA.
AC   Q14624; B7Z545; E9PGN5; Q15135; Q9P190; Q9UQ54;
DE   RecName: Full=Inter-alpha-trypsin inhibitor heavy chain H4;
DE            Short=ITI heavy chain H4;
DE            Short=ITI-HC4;
DE            Short=Inter-alpha-inhibitor heavy chain 4;
DE   AltName: Full=Inter-alpha-trypsin inhibitor family heavy chain-related protein;
DE            Short=IHRP;
DE   AltName: Full=Plasma kallikrein sensitive glycoprotein 120;
DE            Short=Gp120;
DE            Short=PK-120;
DE   Contains:
DE     RecName: Full=70 kDa inter-alpha-trypsin inhibitor heavy chain H4;
DE   Contains:
DE     RecName: Full=35 kDa inter-alpha-trypsin inhibitor heavy chain H4;
DE   Flags: Precursor;
GN   Name=ITIH4; Synonyms=IHRP, ITIHL1, PK120; ORFNames=PRO1851;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006953; P:acute-phase response; IEP:UniProtKB.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:InterPro.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0034097; P:response to cytokine; IEP:UniProtKB.
//
ID   ITIH5_HUMAN             Reviewed;         942 AA.
AC   Q86UX2; Q5T664; Q5T665; Q5T666; Q6AI60; Q6UXB7; Q8TF48; Q8WYV2;
AC   Q96K70;
DE   RecName: Full=Inter-alpha-trypsin inhibitor heavy chain H5;
DE            Short=ITI heavy chain H5;
DE            Short=ITI-HC5;
DE            Short=Inter-alpha-inhibitor heavy chain 5;
DE   Flags: Precursor;
GN   Name=ITIH5; Synonyms=KIAA1953; ORFNames=PP14776, UNQ311/PRO354;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:InterPro.
//
ID   ITIH6_HUMAN             Reviewed;        1313 AA.
AC   Q6UXX5; A6NN03;
DE   RecName: Full=Inter-alpha-trypsin inhibitor heavy chain H6;
DE   AltName: Full=Inter-alpha-trypsin inhibitor heavy chain H5-like protein;
DE            Short=Inter-alpha inhibitor H5-like protein;
DE   Flags: Precursor;
GN   Name=ITIH6; Synonyms=ITIH5L; ORFNames=UNQ6369/PRO21074;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:InterPro.
//
ID   ITK_HUMAN               Reviewed;         620 AA.
AC   Q08881; B2R752; Q32ML7;
DE   RecName: Full=Tyrosine-protein kinase ITK/TSK;
DE            EC=2.7.10.2;
DE   AltName: Full=Interleukin-2-inducible T-cell kinase;
DE            Short=IL-2-inducible T-cell kinase;
DE   AltName: Full=Kinase EMT;
DE   AltName: Full=T-cell-specific kinase;
DE   AltName: Full=Tyrosine-protein kinase Lyk;
GN   Name=ITK; Synonyms=EMT, LYK;
DR   GuidetoPHARMACOLOGY; 2046; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0001816; P:cytokine production; ISS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032633; P:interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0001865; P:NK T cell differentiation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
//
ID   ITLN2_HUMAN             Reviewed;         325 AA.
AC   Q8WWU7; Q5VYI0;
DE   RecName: Full=Intelectin-2;
DE   AltName: Full=Endothelial lectin HL-2;
DE   Flags: Precursor;
GN   Name=ITLN2; ORFNames=UNQ2789/PRO7179;
//
ID   ITM2A_HUMAN             Reviewed;         263 AA.
AC   O43736; B2R7X5; B4E062;
DE   RecName: Full=Integral membrane protein 2A;
DE   AltName: Full=Protein E25;
GN   Name=ITM2A; ORFNames=UNQ603/PRO1189;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ITM2B_HUMAN             Reviewed;         266 AA.
AC   Q9Y287; Q9NYH1;
DE   RecName: Full=Integral membrane protein 2B;
DE   AltName: Full=Immature BRI2;
DE            Short=imBRI2;
DE   AltName: Full=Protein E25B;
DE   AltName: Full=Transmembrane protein BRI;
DE            Short=Bri;
DE   Contains:
DE     RecName: Full=BRI2, membrane form;
DE     AltName: Full=Mature BRI2;
DE              Short=mBRI2;
DE   Contains:
DE     RecName: Full=BRI2 intracellular domain;
DE              Short=BRI2 ICD;
DE   Contains:
DE     RecName: Full=BRI2C, soluble form;
DE   Contains:
DE     RecName: Full=Bri23 peptide;
DE              Short=Bri2-23;
DE     AltName: Full=ABri23;
DE     AltName: Full=C-terminal peptide;
DE     AltName: Full=P23 peptide;
GN   Name=ITM2B; Synonyms=BRI, BRI2;
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   ITLN1_HUMAN             Reviewed;         313 AA.
AC   Q8WWA0; Q5IWS4; Q5VYI4; Q6YDJ3; Q9NP67;
DE   RecName: Full=Intelectin-1;
DE            Short=ITLN-1;
DE   AltName: Full=Endothelial lectin HL-1;
DE   AltName: Full=Galactofuranose-binding lectin;
DE   AltName: Full=Intestinal lactoferrin receptor;
DE   AltName: Full=Omentin;
DE   Flags: Precursor;
GN   Name=ITLN1; Synonyms=INTL, ITLN, LFR; ORFNames=UNQ640/PRO1270;
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009624; P:response to nematode; ISS:UniProtKB.
//
ID   ITM2C_HUMAN             Reviewed;         267 AA.
AC   Q9NQX7; B3KPG4; Q4G0A8; Q53H84; Q6IAE7; Q86VK5; Q8N288; Q8TAW0;
AC   Q9BUP8;
DE   RecName: Full=Integral membrane protein 2C;
DE   AltName: Full=Cerebral protein 14;
DE   AltName: Full=Transmembrane protein BRI3;
DE   Contains:
DE     RecName: Full=CT-BRI3;
GN   Name=ITM2C; Synonyms=BRI3; ORFNames=hucep-14, NPD018, PSEC0047;
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0001540; F:beta-amyloid binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
//
ID   ITPA_HUMAN              Reviewed;         194 AA.
AC   Q9BY32; A2A2N2; A4UIM5; B2BCH7; O14878; Q5JWH4; Q9BYN1; Q9BYX0;
AC   Q9H3H8;
DE   RecName: Full=Inosine triphosphate pyrophosphatase;
DE            Short=ITPase;
DE            Short=Inosine triphosphatase;
DE            EC=3.6.1.19;
DE   AltName: Full=Non-canonical purine NTP pyrophosphatase;
DE   AltName: Full=Non-standard purine NTP pyrophosphatase;
DE   AltName: Full=Nucleoside-triphosphate diphosphatase;
DE   AltName: Full=Nucleoside-triphosphate pyrophosphatase;
DE            Short=NTPase;
DE   AltName: Full=Putative oncogene protein hlc14-06-p;
GN   Name=ITPA; Synonyms=C20orf37; ORFNames=My049, OK/SW-cl.9;
DR   GO; GO:0035870; F:dITP diphosphatase activity; EXP:Reactome.
DR   GO; GO:0036220; F:ITP diphosphatase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0036222; F:XTP diphosphatase activity; EXP:Reactome.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0009204; P:deoxyribonucleoside triphosphate catabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006193; P:ITP catabolic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ITPK1_HUMAN             Reviewed;         414 AA.
AC   Q13572; Q9BTL6; Q9H2E7;
DE   RecName: Full=Inositol-tetrakisphosphate 1-kinase;
DE            EC=2.7.1.134;
DE   AltName: Full=Inositol 1,3,4-trisphosphate 5/6-kinase;
DE            Short=Inositol-triphosphate 5/6-kinase;
DE            Short=Ins(1,3,4)P(3) 5/6-kinase;
DE            EC=2.7.1.159;
GN   Name=ITPK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0047325; F:inositol tetrakisphosphate 1-kinase activity; TAS:Reactome.
DR   GO; GO:0052825; F:inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity; TAS:Reactome.
DR   GO; GO:0052831; F:inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity; TAS:Reactome.
DR   GO; GO:0052830; F:inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity; TAS:Reactome.
DR   GO; GO:0052726; F:inositol-1,3,4-trisphosphate 5-kinase activity; TAS:Reactome.
DR   GO; GO:0052725; F:inositol-1,3,4-trisphosphate 6-kinase activity; TAS:Reactome.
DR   GO; GO:0052835; F:inositol-3,4,6-trisphosphate 1-kinase activity; TAS:Reactome.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0032957; P:inositol trisphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ITPR1_HUMAN             Reviewed;        2758 AA.
AC   Q14643; E7EPX7; E9PDE9; Q14660; Q99897;
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor type 1;
DE   AltName: Full=IP3 receptor isoform 1;
DE            Short=IP3R 1;
DE            Short=InsP3R1;
DE   AltName: Full=Type 1 inositol 1,4,5-trisphosphate receptor;
DE            Short=Type 1 InsP3 receptor;
GN   Name=ITPR1; Synonyms=INSP3R1;
DR   GuidetoPHARMACOLOGY; 743; -.
DR   GO; GO:0015085; F:calcium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ISS:UniProtKB.
DR   GO; GO:0005218; F:intracellular ligand-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; ISS:GOC.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050882; P:voluntary musculoskeletal movement; IEA:Ensembl.
//
ID   ITPR2_HUMAN             Reviewed;        2701 AA.
AC   Q14571; O94773;
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor type 2;
DE   AltName: Full=IP3 receptor isoform 2;
DE            Short=IP3R 2;
DE            Short=InsP3R2;
DE   AltName: Full=Type 2 inositol 1,4,5-trisphosphate receptor;
DE            Short=Type 2 InsP3 receptor;
GN   Name=ITPR2;
DR   GuidetoPHARMACOLOGY; 744; -.
DR   GO; GO:0015085; F:calcium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; TAS:ProtInc.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   ITPR3_HUMAN             Reviewed;        2671 AA.
AC   Q14573; Q14649; Q5TAQ2;
DE   RecName: Full=Inositol 1,4,5-trisphosphate receptor type 3;
DE   AltName: Full=IP3 receptor isoform 3;
DE            Short=IP3R 3;
DE            Short=InsP3R3;
DE   AltName: Full=Type 3 inositol 1,4,5-trisphosphate receptor;
DE            Short=Type 3 InsP3 receptor;
GN   Name=ITPR3;
DR   GuidetoPHARMACOLOGY; 745; -.
DR   GO; GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; ISS:BHF-UCL.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ISS:UniProtKB.
DR   GO; GO:0000822; F:inositol hexakisphosphate binding; ISS:BHF-UCL.
DR   GO; GO:0005218; F:intracellular ligand-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; ISS:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; ISS:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0050913; P:sensory perception of bitter taste; IEA:Ensembl.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IEA:Ensembl.
DR   GO; GO:0050917; P:sensory perception of umami taste; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ITSN1_HUMAN             Reviewed;        1721 AA.
AC   Q15811; A7Y322; A8CTX8; A8CTY3; A8CTY7; A8D7D0; A8DCP3; B4DTM2;
AC   E7ERJ1; E9PE44; E9PG01; E9PHV2; O95216; Q0PW94; Q0PW95; Q0PW97;
AC   Q14BD3; Q1ED40; Q20BK3; Q9UET5; Q9UK60; Q9UNK1; Q9UNK2; Q9UQ92;
DE   RecName: Full=Intersectin-1;
DE   AltName: Full=SH3 domain-containing protein 1A;
DE   AltName: Full=SH3P17;
GN   Name=ITSN1; Synonyms=ITSN, SH3D1A;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0019209; F:kinase activator activity; IEA:Ensembl.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; NAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
//
ID   ITSN2_HUMAN             Reviewed;        1697 AA.
AC   Q9NZM3; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9ULG4;
DE   RecName: Full=Intersectin-2;
DE   AltName: Full=SH3 domain-containing protein 1B;
DE   AltName: Full=SH3P18;
DE   AltName: Full=SH3P18-like WASP-associated protein;
GN   Name=ITSN2; Synonyms=KIAA1256, SH3D1B, SWAP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
//
ID   IV1U1_HUMAN             Reviewed;         120 AA.
AC   A6NJS3;
DE   RecName: Full=Putative V-set and immunoglobulin domain-containing-like protein IGHV1OR21-1;
DE   AltName: Full=Immunoglobulin heavy variable 1 orphon 21-1;
DE   Flags: Precursor;
GN   Name=IGHV1OR21-1;
//
ID   IV4F8_HUMAN             Reviewed;         123 AA.
AC   A6NJ16;
DE   RecName: Full=Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8;
DE   AltName: Full=Immunoglobulin heavy variable 4 orphon 15-8;
DE   AltName: Full=Putative V-set and immunoglobulin domain-containing protein 6;
DE   Flags: Precursor;
GN   Name=IGHV4OR15-8; Synonyms=VSIG6;
//
ID   IVD_HUMAN               Reviewed;         423 AA.
AC   P26440; B2RCV5; B3KVI7; Q96AF6;
DE   RecName: Full=Isovaleryl-CoA dehydrogenase, mitochondrial;
DE            Short=IVD;
DE            EC=1.3.8.4;
DE   Flags: Precursor;
GN   Name=IVD;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0008470; F:isovaleryl-CoA dehydrogenase activity; ISS:BHF-UCL.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006552; P:leucine catabolic process; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   IWS1_HUMAN              Reviewed;         819 AA.
AC   Q96ST2; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q9NV97; Q9NWH8;
DE   RecName: Full=Protein IWS1 homolog;
DE   AltName: Full=IWS1-like protein;
GN   Name=IWS1; Synonyms=IWS1L;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:2001253; P:regulation of histone H3-K36 trimethylation; IMP:UniProtKB.
DR   GO; GO:0090239; P:regulation of histone H4 acetylation; IMP:UniProtKB.
DR   GO; GO:0010793; P:regulation of mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0050684; P:regulation of mRNA processing; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   IYD1_HUMAN              Reviewed;         289 AA.
AC   Q6PHW0; C9JFW2; Q2VPW0; Q2VPW1; Q5F1L5; Q5F1L6; Q5THM4; Q6ZP69;
AC   Q7Z7D7; Q7Z7D8;
DE   RecName: Full=Iodotyrosine dehalogenase 1;
DE            Short=IYD-1;
DE            EC=1.22.1.1;
DE   Flags: Precursor;
GN   Name=IYD; Synonyms=C6orf71, DEHAL1;
DR   GO; GO:0004447; F:iodide peroxidase activity; IEA:Ensembl.
DR   GO; GO:0016491; F:oxidoreductase activity; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; TAS:Reactome.
//
ID   IZUM1_HUMAN             Reviewed;         350 AA.
AC   Q8IYV9; Q6Q8P6; Q6Q8P7;
DE   RecName: Full=Izumo sperm-egg fusion protein 1;
DE   AltName: Full=Oocyte binding/fusion factor;
DE            Short=OBF;
DE   AltName: Full=Sperm-specific protein izumo;
DE   Flags: Precursor;
GN   Name=IZUMO1;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IC:HGNC.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IDA:HGNC.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   IZUM3_HUMAN             Reviewed;         239 AA.
AC   Q5VZ72;
DE   RecName: Full=Izumo sperm-egg fusion protein 3;
DE   Flags: Precursor;
GN   Name=IZUMO3; Synonyms=C9orf134;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
//
ID   IZUM2_HUMAN             Reviewed;         221 AA.
AC   Q6UXV1; Q5GRG3; Q5GRG4; Q6ZNM5; Q8NHR8;
DE   RecName: Full=Izumo sperm-egg fusion protein 2;
DE   Flags: Precursor;
GN   Name=IZUMO2; Synonyms=C19orf41, SCRL; ORFNames=UNQ6978/PRO21961;
//
ID   IZUM4_HUMAN             Reviewed;         232 AA.
AC   Q1ZYL8; A7RA93; A7RA94; Q6UXA2; Q96FT6; Q96L02;
DE   RecName: Full=Izumo sperm-egg fusion protein 4;
DE   AltName: Full=Sperm 22 kDa protein c113;
DE   Flags: Precursor;
GN   Name=IZUMO4; Synonyms=C19orf36; ORFNames=UNQ831/PRO1758;
//
ID   JADE1_HUMAN             Reviewed;         842 AA.
AC   Q6IE81; D3DNY0; D3DNY1; Q4W5D5; Q6ZSL7; Q8NC41; Q96JL8; Q96SQ1;
AC   Q9H692;
DE   RecName: Full=Protein Jade-1;
DE   AltName: Full=Jade family PHD finger protein 1;
DE   AltName: Full=PHD finger protein 17;
GN   Name=JADE1; Synonyms=KIAA1807, PHF17;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   JADE3_HUMAN             Reviewed;         823 AA.
AC   Q92613; Q6IE79;
DE   RecName: Full=Protein Jade-3;
DE   AltName: Full=Jade family PHD finger protein 3;
DE   AltName: Full=PHD finger protein 16;
GN   Name=JADE3; Synonyms=KIAA0215, PHF16;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
//
ID   JADE2_HUMAN             Reviewed;         790 AA.
AC   Q9NQC1; D3DQA3; Q6IE80; Q8TEK0; Q92513; Q96GQ6;
DE   RecName: Full=Protein Jade-2;
DE   AltName: Full=Jade family PHD finger protein 2;
DE   AltName: Full=PHD finger protein 15;
GN   Name=JADE2; Synonyms=KIAA0239, PHF15;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
//
ID   JAG1_HUMAN              Reviewed;        1218 AA.
AC   P78504; A0AV43; O14902; O15122; Q15816;
DE   RecName: Full=Protein jagged-1;
DE            Short=Jagged1;
DE            Short=hJ1;
DE   AltName: CD_antigen=CD339;
DE   Flags: Precursor;
GN   Name=JAG1; Synonyms=JAGL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0005112; F:Notch binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0035909; P:aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0061309; P:cardiac neural crest cell development involved in outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060411; P:cardiac septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001709; P:cell fate determination; NAS:UniProtKB.
DR   GO; GO:0072017; P:distal tubule development; IEA:Ensembl.
DR   GO; GO:0061444; P:endocardial cushion cell development; ISS:BHF-UCL.
DR   GO; GO:0045446; P:endothelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0072070; P:loop of Henle development; IEA:Ensembl.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0045445; P:myoblast differentiation; NAS:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:2000737; P:negative regulation of stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; IMP:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045639; P:positive regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0061156; P:pulmonary artery morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0030334; P:regulation of cell migration; NAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0002456; P:T cell mediated immunity; IMP:UniProt.
//
ID   JAG2_HUMAN              Reviewed;        1238 AA.
AC   Q9Y219; Q9UE17; Q9UE99; Q9UNK8; Q9Y6P9; Q9Y6Q0;
DE   RecName: Full=Protein jagged-2;
DE            Short=Jagged2;
DE            Short=hJ2;
DE   Flags: Precursor;
GN   Name=JAG2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0005112; F:Notch binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009912; P:auditory receptor cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:1990134; P:epithelial cell apoptotic process involved in palatal shelf morphogenesis; IEA:Ensembl.
DR   GO; GO:0042492; P:gamma-delta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; NAS:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; NAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045061; P:thymic T cell selection; IDA:UniProtKB.
//
ID   JAGN1_HUMAN             Reviewed;         183 AA.
AC   Q8N5M9; Q8NCF6; Q96SW1;
DE   RecName: Full=Protein jagunal homolog 1;
GN   Name=JAGN1;
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:InterPro.
//
ID   JAK1_HUMAN              Reviewed;        1154 AA.
AC   P23458; Q59GQ2; Q9UD26;
DE   RecName: Full=Tyrosine-protein kinase JAK1;
DE            EC=2.7.10.2;
DE   AltName: Full=Janus kinase 1;
DE            Short=JAK-1;
GN   Name=JAK1; Synonyms=JAK1A, JAK1B;
DR   GuidetoPHARMACOLOGY; 2047; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; EXP:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0038110; P:interleukin-2-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0046677; P:response to antibiotic; IDA:MGI.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   JAK2_HUMAN              Reviewed;        1132 AA.
AC   O60674; O14636; O75297;
DE   RecName: Full=Tyrosine-protein kinase JAK2;
DE            EC=2.7.10.2;
DE   AltName: Full=Janus kinase 2;
DE            Short=JAK-2;
GN   Name=JAK2;
DR   GuidetoPHARMACOLOGY; 2048; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0035401; F:histone kinase activity (H3-Y41 specific); IDA:UniProtKB.
DR   GO; GO:0005143; F:interleukin-12 receptor binding; ISS:BHF-UCL.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:ProtInc.
DR   GO; GO:0019901; F:protein kinase binding; IDA:BHF-UCL.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; NAS:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0097296; P:activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0042977; P:activation of JAK2 kinase activity; ISS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035409; P:histone H3-Y41 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0034050; P:host programmed cell death induced by symbiont; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0035722; P:interleukin-12-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:BHF-UCL.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; ISS:UniProtKB.
DR   GO; GO:0061180; P:mammary gland epithelium development; ISS:BHF-UCL.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0031959; P:mineralocorticoid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; ISS:BHF-UCL.
DR   GO; GO:0045822; P:negative regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0050867; P:positive regulation of cell activation; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0060399; P:positive regulation of growth hormone receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:BHF-UCL.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IEA:Ensembl.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0050727; P:regulation of inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0046677; P:response to antibiotic; IDA:MGI.
DR   GO; GO:0033194; P:response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0070671; P:response to interleukin-12; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
DR   GO; GO:0007262; P:STAT protein import into nucleus; ISS:BHF-UCL.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007260; P:tyrosine phosphorylation of STAT protein; ISS:BHF-UCL.
DR   GO; GO:0042508; P:tyrosine phosphorylation of Stat1 protein; IEA:Ensembl.
DR   GO; GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
DR   GO; GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IEA:Ensembl.
//
ID   JAK3_HUMAN              Reviewed;        1124 AA.
AC   P52333; Q13259; Q13260; Q13611; Q8N1E8; Q99699; Q9Y6S2;
DE   RecName: Full=Tyrosine-protein kinase JAK3;
DE            EC=2.7.10.2;
DE   AltName: Full=Janus kinase 3;
DE            Short=JAK-3;
DE   AltName: Full=Leukocyte janus kinase;
DE            Short=L-JAK;
GN   Name=JAK3;
DR   GuidetoPHARMACOLOGY; 2049; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; ISS:BHF-UCL.
DR   GO; GO:0030183; P:B cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0035771; P:interleukin-4-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:BHF-UCL.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:UniProtKB.
DR   GO; GO:0002731; P:negative regulation of dendritic cell cytokine production; ISS:BHF-UCL.
DR   GO; GO:0045221; P:negative regulation of FasL biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; ISS:BHF-UCL.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0050868; P:negative regulation of T cell activation; ISS:BHF-UCL.
DR   GO; GO:0045626; P:negative regulation of T-helper 1 cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:2000670; P:positive regulation of dendritic cell apoptotic process; IEA:Ensembl.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0070232; P:regulation of T cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0070672; P:response to interleukin-15; TAS:BHF-UCL.
DR   GO; GO:0070669; P:response to interleukin-2; TAS:BHF-UCL.
DR   GO; GO:0070670; P:response to interleukin-4; IDA:BHF-UCL.
DR   GO; GO:0071104; P:response to interleukin-9; TAS:BHF-UCL.
DR   GO; GO:0007262; P:STAT protein import into nucleus; TAS:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; TAS:UniProtKB.
DR   GO; GO:0007260; P:tyrosine phosphorylation of STAT protein; TAS:UniProtKB.
//
ID   JAM1_HUMAN              Reviewed;         299 AA.
AC   Q9Y624;
DE   RecName: Full=Junctional adhesion molecule A;
DE            Short=JAM-A;
DE   AltName: Full=Junctional adhesion molecule 1;
DE            Short=JAM-1;
DE   AltName: Full=Platelet F11 receptor;
DE   AltName: Full=Platelet adhesion molecule 1;
DE            Short=PAM-1;
DE   AltName: CD_antigen=CD321;
DE   Flags: Precursor;
GN   Name=F11R; Synonyms=JAM1, JCAM; ORFNames=UNQ264/PRO301;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   JAM2_HUMAN              Reviewed;         298 AA.
AC   P57087; B2R6T9; B4DGT9; Q6UXG6; Q6YNC1;
DE   RecName: Full=Junctional adhesion molecule B;
DE            Short=JAM-B;
DE   AltName: Full=Junctional adhesion molecule 2;
DE            Short=JAM-2;
DE   AltName: Full=Vascular endothelial junction-associated molecule;
DE            Short=VE-JAM;
DE   AltName: CD_antigen=CD322;
DE   Flags: Precursor;
GN   Name=JAM2; Synonyms=C21orf43, VEJAM; ORFNames=UNQ219/PRO245;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
//
ID   JAM3_HUMAN              Reviewed;         310 AA.
AC   Q9BX67; B3KWG9; Q8WWL8; Q96FL1;
DE   RecName: Full=Junctional adhesion molecule C;
DE            Short=JAM-C;
DE   AltName: Full=JAM-2;
DE   AltName: Full=Junctional adhesion molecule 3;
DE            Short=JAM-3;
DE   Flags: Precursor;
GN   Name=JAM3; ORFNames=UNQ859/PRO1868;
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002250; P:adaptive immune response; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0002523; P:leukocyte migration involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0002318; P:myeloid progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0001780; P:neutrophil homeostasis; IEA:Ensembl.
DR   GO; GO:0090138; P:regulation of actin cytoskeleton organization by cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0090022; P:regulation of neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   JAML1_HUMAN             Reviewed;         394 AA.
AC   Q86YT9; B0YIV1; B0YIV2; Q496M1; Q5DTC6; Q7Z499; Q8N9I7; Q8NF70;
DE   RecName: Full=Junctional adhesion molecule-like;
DE   AltName: Full=Adhesion molecule interacting with CXADR antigen 1;
DE   AltName: Full=Dendritic cell-specific protein CREA7-1;
DE   Flags: Precursor;
GN   Name=AMICA1; Synonyms=JAML; ORFNames=UNQ722/PRO1387;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0046629; P:gamma-delta T cell activation; ISS:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0035696; P:monocyte extravasation; IMP:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IMP:UniProtKB.
DR   GO; GO:0072672; P:neutrophil extravasation; IMP:UniProtKB.
DR   GO; GO:0060054; P:positive regulation of epithelial cell proliferation involved in wound healing; ISS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   JAZF1_HUMAN             Reviewed;         243 AA.
AC   Q86VZ6; A4D195; Q8N3L7;
DE   RecName: Full=Juxtaposed with another zinc finger protein 1;
DE   AltName: Full=TAK1-interacting protein 27;
DE   AltName: Full=Zinc finger protein 802;
GN   Name=JAZF1; Synonyms=TIP27, ZNF802;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:MGI.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   JARD2_HUMAN             Reviewed;        1246 AA.
AC   Q92833; A8K9Z6; B7Z5S5; B7Z8L0; Q5U5L5; Q86X63;
DE   RecName: Full=Protein Jumonji;
DE   AltName: Full=Jumonji/ARID domain-containing protein 2;
GN   Name=JARID2; Synonyms=JMJ;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   JCAD_HUMAN              Reviewed;        1359 AA.
AC   Q9P266; Q5HYA7; Q5T992; Q86WZ9; Q9BYJ2;
DE   RecName: Full=Junctional protein associated with coronary artery disease;
DE            Short=JCAD;
GN   Name=KIAA1462; Synonyms=JCAD;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   JDP2_HUMAN              Reviewed;         163 AA.
AC   Q8WYK2; J3KN58; O95430; Q9UIE4;
DE   RecName: Full=Jun dimerization protein 2;
GN   Name=JDP2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   JERKL_HUMAN             Reviewed;         524 AA.
AC   Q9Y4A0; A8K3G4; B2RAJ3; Q32MC2;
DE   RecName: Full=Jerky protein homolog-like;
DE   AltName: Full=Human homolog of mouse jerky gene protein;
DE            Short=HHMJG;
GN   Name=JRKL;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
//
ID   JERKY_HUMAN             Reviewed;         520 AA.
AC   O75564; O75565;
DE   RecName: Full=Jerky protein homolog;
GN   Name=JRK; Synonyms=JH8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   JHD2C_HUMAN             Reviewed;        2540 AA.
AC   Q15652; A0T124; Q5SQZ8; Q5SQZ9; Q5SR00; Q7Z3E7; Q8N3U0; Q96KB9;
AC   Q9P2G7;
DE   RecName: Full=Probable JmjC domain-containing histone demethylation protein 2C;
DE            EC=1.14.11.-;
DE   AltName: Full=Jumonji domain-containing protein 1C;
DE   AltName: Full=Thyroid receptor-interacting protein 8;
DE            Short=TR-interacting protein 8;
DE            Short=TRIP-8;
GN   Name=JMJD1C; Synonyms=JHDM2C, KIAA1380, TRIP8;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   JIP1_HUMAN              Reviewed;         711 AA.
AC   Q9UQF2; D3DQP4; O43407;
DE   RecName: Full=C-Jun-amino-terminal kinase-interacting protein 1;
DE            Short=JIP-1;
DE            Short=JNK-interacting protein 1;
DE   AltName: Full=Islet-brain 1;
DE            Short=IB-1;
DE   AltName: Full=JNK MAP kinase scaffold protein 1;
DE   AltName: Full=Mitogen-activated protein kinase 8-interacting protein 1;
GN   Name=MAPK8IP1; Synonyms=IB1, JIP1, PRKM8IP;
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0007258; P:JUN phosphorylation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IPI:GOC.
DR   GO; GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   JIP2_HUMAN              Reviewed;         824 AA.
AC   Q13387; Q96G62; Q99771; Q9NZ59; Q9UKQ4;
DE   RecName: Full=C-Jun-amino-terminal kinase-interacting protein 2;
DE            Short=JIP-2;
DE            Short=JNK-interacting protein 2;
DE   AltName: Full=Islet-brain-2;
DE            Short=IB-2;
DE   AltName: Full=JNK MAP kinase scaffold protein 2;
DE   AltName: Full=Mitogen-activated protein kinase 8-interacting protein 2;
GN   Name=MAPK8IP2; Synonyms=IB2, JIP2, PRKM8IPL;
DR   GO; GO:0001540; F:beta-amyloid binding; NAS:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; ISS:UniProtKB.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:MGI.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0001662; P:behavioral fear response; ISS:BHF-UCL.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; IDA:MGI.
DR   GO; GO:0046958; P:nonassociative learning; ISS:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:0009967; P:positive regulation of signal transduction; NAS:GOC.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0010469; P:regulation of receptor activity; ISS:BHF-UCL.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0007172; P:signal complex assembly; TAS:ProtInc.
DR   GO; GO:0035176; P:social behavior; ISS:BHF-UCL.
//
ID   JIP3_HUMAN              Reviewed;        1336 AA.
AC   Q9UPT6; A2A2B3; A7E2B3; Q96RY4; Q9H4I4; Q9H7P1; Q9NUG0;
DE   RecName: Full=C-Jun-amino-terminal kinase-interacting protein 3;
DE            Short=JIP-3;
DE            Short=JNK-interacting protein 3;
DE   AltName: Full=JNK MAP kinase scaffold protein 3;
DE   AltName: Full=Mitogen-activated protein kinase 8-interacting protein 3;
GN   Name=MAPK8IP3; Synonyms=JIP3, KIAA1066;
DR   GO; GO:0019894; F:kinesin binding; ISS:UniProtKB.
DR   GO; GO:0005078; F:MAP-kinase scaffold activity; ISS:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0060425; P:lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   JIP4_HUMAN              Reviewed;        1321 AA.
AC   O60271; A6H8U5; A8MSX0; B4DHH2; O60905; Q3KQU8; Q3MKM7; Q86WC7;
AC   Q86WC8; Q8IZX7; Q96II0; Q9H811;
DE   RecName: Full=C-Jun-amino-terminal kinase-interacting protein 4;
DE            Short=JIP-4;
DE            Short=JNK-interacting protein 4;
DE   AltName: Full=Cancer/testis antigen 89;
DE            Short=CT89;
DE   AltName: Full=Human lung cancer oncogene 6 protein;
DE            Short=HLC-6;
DE   AltName: Full=JNK-associated leucine-zipper protein;
DE            Short=JLP;
DE   AltName: Full=Mitogen-activated protein kinase 8-interacting protein 4;
DE   AltName: Full=Proliferation-inducing protein 6;
DE   AltName: Full=Protein highly expressed in testis;
DE            Short=PHET;
DE   AltName: Full=Sperm surface protein;
DE   AltName: Full=Sperm-associated antigen 9;
DE   AltName: Full=Sperm-specific protein;
DE   AltName: Full=Sunday driver 1;
GN   Name=SPAG9; Synonyms=HSS, KIAA0516, MAPK8IP4, SYD1; ORFNames=HLC6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0090074; P:negative regulation of protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:MGI.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
//
ID   JKAMP_HUMAN             Reviewed;         326 AA.
AC   Q9P055; B4DP67; Q6FIB6; Q6IAJ2; Q7Z5D4; Q86SY6; Q9H0Q6; Q9H2W0;
AC   Q9HAH5; Q9P0R3;
DE   RecName: Full=JNK1/MAPK8-associated membrane protein;
DE            Short=JKAMP;
DE   AltName: Full=JNK1-associated membrane protein;
DE            Short=JAMP;
DE   AltName: Full=Medulloblastoma antigen MU-MB-50.4;
GN   Name=JKAMP; Synonyms=C14orf100, JAMP;
GN   ORFNames=CDA06, HSPC213, HSPC327;
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   JKIP1_HUMAN             Reviewed;         626 AA.
AC   Q96N16; A6H2J2; A6H2J3; A6H2J4; A6H2J5; A8MTK6; B4DHZ8; B8ZZR7;
AC   D3DVT0; Q86Y69; Q8N7G3;
DE   RecName: Full=Janus kinase and microtubule-interacting protein 1;
DE   AltName: Full=GABA-B receptor-binding protein;
DE   AltName: Full=Multiple alpha-helices and RNA-linker protein 1;
DE            Short=Marlin-1;
GN   Name=JAKMIP1; Synonyms=GABABRBP, JAMIP1, MARLIN1;
DR   GO; GO:0050811; F:GABA receptor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:MGI.
DR   GO; GO:0050890; P:cognition; IMP:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   JKIP2_HUMAN             Reviewed;         810 AA.
AC   Q96AA8; A4ZZA7; A8K5G5; O60302; Q548S1;
DE   RecName: Full=Janus kinase and microtubule-interacting protein 2;
DE   AltName: Full=CTCL tumor antigen HD-CL-04;
DE   AltName: Full=Neuroendocrine long coiled-coil protein 1;
GN   Name=JAKMIP2; Synonyms=JAMIP2, KIAA0555, NECC1;
//
ID   JKIP3_HUMAN             Reviewed;         844 AA.
AC   Q5VZ66; A6PW00; Q69YM6; Q6ZT29;
DE   RecName: Full=Janus kinase and microtubule-interacting protein 3;
DE   AltName: Full=Neuroendocrine long coiled-coil protein 2;
GN   Name=JAKMIP3; Synonyms=C10orf14, C10orf39, JAMIP3, NECC2;
//
ID   JMJD4_HUMAN             Reviewed;         463 AA.
AC   Q9H9V9; Q5TBZ1; Q5TBZ6; Q9H970;
DE   RecName: Full=JmjC domain-containing protein 4;
DE   AltName: Full=Jumonji domain-containing protein 4;
GN   Name=JMJD4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   JMJD6_HUMAN             Reviewed;         403 AA.
AC   Q6NYC1; B3KMN8; B4DGX1; Q86VY0; Q8IUM5; Q9Y4E2;
DE   RecName: Full=Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6;
DE            EC=1.14.11.-;
DE   AltName: Full=Histone arginine demethylase JMJD6;
DE   AltName: Full=JmjC domain-containing protein 6;
DE   AltName: Full=Jumonji domain-containing protein 6;
DE   AltName: Full=Lysyl-hydroxylase JMJD6;
DE   AltName: Full=Peptide-lysine 5-dioxygenase JMJD6;
DE   AltName: Full=Phosphatidylserine receptor;
DE            Short=Protein PTDSR;
GN   Name=JMJD6; Synonyms=KIAA0585, PTDSR;
DR   GO; GO:0033746; F:histone demethylase activity (H3-R2 specific); IDA:UniProtKB.
DR   GO; GO:0033749; F:histone demethylase activity (H4-R3 specific); IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0070815; F:peptidyl-lysine 5-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0070078; P:histone H3-R2 demethylation; IDA:BHF-UCL.
DR   GO; GO:0070079; P:histone H4-R3 demethylation; IDA:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0042116; P:macrophage activation; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0018395; P:peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; IDA:UniProtKB.
DR   GO; GO:0070782; P:phosphatidylserine exposure on apoptotic cell surface; IEA:Ensembl.
DR   GO; GO:0043654; P:recognition of apoptotic cell; IEA:Ensembl.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   JMJD8_HUMAN             Reviewed;         334 AA.
AC   Q96S16; B2RNS7; D3DU58; Q4PKE3; Q4VBY1; Q6GMW5; Q71RB8;
DE   RecName: Full=JmjC domain-containing protein 8;
DE   AltName: Full=Jumonji domain-containing protein 8;
GN   Name=JMJD8; Synonyms=C16orf20; ORFNames=PP14397;
//
ID   JMJD7_HUMAN             Reviewed;         316 AA.
AC   P0C870; A5D6V5; O95712; Q59GF9; Q8TB10; Q9UKV7;
DE   RecName: Full=JmjC domain-containing protein 7;
DE   AltName: Full=Jumonji domain-containing protein 7;
GN   Name=JMJD7;
//
ID   JMY_HUMAN               Reviewed;         988 AA.
AC   Q8N9B5; A1L4P5; B5MDS2; B5MDT0;
DE   RecName: Full=Junction-mediating and -regulatory protein;
GN   Name=JMY;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:HGNC.
DR   GO; GO:0070060; P:'de novo' actin filament nucleation; ISS:UniProtKB.
DR   GO; GO:0070358; P:actin polymerization-dependent cell motility; ISS:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:HGNC.
//
ID   JOS1_HUMAN              Reviewed;         202 AA.
AC   Q15040; A8K712;
DE   RecName: Full=Josephin-1;
DE            EC=3.4.19.12;
DE   AltName: Full=Josephin domain-containing protein 1;
GN   Name=JOSD1; Synonyms=JSPH1, KIAA0063;
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
//
ID   JOS2_HUMAN              Reviewed;         188 AA.
AC   Q8TAC2; M0QX25;
DE   RecName: Full=Josephin-2;
DE            EC=3.4.19.12;
DE   AltName: Full=Josephin domain-containing protein 2;
GN   Name=JOSD2; ORFNames=SBBI54;
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
//
ID   JPH1_HUMAN              Reviewed;         661 AA.
AC   Q9HDC5; B2RTZ0;
DE   RecName: Full=Junctophilin-1;
DE            Short=JP-1;
DE   AltName: Full=Junctophilin type 1;
GN   Name=JPH1; Synonyms=JP1;
DR   GO; GO:0008307; F:structural constituent of muscle; IEA:Ensembl.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
//
ID   JPH2_HUMAN              Reviewed;         696 AA.
AC   Q9BR39; E1P5X1; O95913; Q5JY74; Q9UJN4;
DE   RecName: Full=Junctophilin-2;
DE            Short=JP-2;
DE   AltName: Full=Junctophilin type 2;
GN   Name=JPH2; Synonyms=JP2;
DR   GO; GO:0015278; F:calcium-release channel activity; IDA:UniProtKB.
DR   GO; GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0055074; P:calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; IDA:UniProtKB.
DR   GO; GO:0055024; P:regulation of cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
//
ID   JPH3_HUMAN              Reviewed;         748 AA.
AC   Q8WXH2; D3DUN2; Q8N471; Q9HDC3; Q9HDC4;
DE   RecName: Full=Junctophilin-3;
DE            Short=JP-3;
DE   AltName: Full=Junctophilin type 3;
DE   AltName: Full=Trinucleotide repeat-containing gene 22 protein;
GN   Name=JPH3; Synonyms=JP3, TNRC22;
DR   GO; GO:0015278; F:calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.
DR   GO; GO:0035640; P:exploration behavior; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0040011; P:locomotion; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
//
ID   JPH4_HUMAN              Reviewed;         628 AA.
AC   Q96JJ6; D3DS53; Q8ND44; Q96DQ0;
DE   RecName: Full=Junctophilin-4;
DE            Short=JP-4;
DE   AltName: Full=Junctophilin-like 1 protein;
GN   Name=JPH4; Synonyms=JPHL1, KIAA1831;
DR   GO; GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
//
ID   JSPR1_HUMAN             Reviewed;         331 AA.
AC   Q96MG2;
DE   RecName: Full=Junctional sarcoplasmic reticulum protein 1;
DE   AltName: Full=Junctional-face membrane protein of 45 kDa homolog;
DE            Short=JP-45;
GN   Name=JSRP1; Synonyms=JP45;
DR   GO; GO:0072657; P:protein localization to membrane; IEA:Ensembl.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0003009; P:skeletal muscle contraction; IDA:UniProtKB.
//
ID   JUNB_HUMAN              Reviewed;         347 AA.
AC   P17275; Q96GH3;
DE   RecName: Full=Transcription factor jun-B;
GN   Name=JUNB;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0033687; P:osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   JUND_HUMAN              Reviewed;         347 AA.
AC   P17535; Q53EK9;
DE   RecName: Full=Transcription factor jun-D;
GN   Name=JUND;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   JUNO_HUMAN              Reviewed;         250 AA.
AC   A6ND01;
DE   RecName: Full=Sperm-egg fusion protein Juno;
DE   AltName: Full=Folate receptor 4;
DE   AltName: Full=Folate receptor delta;
DE            Short=FR-delta;
DE   Flags: Precursor;
GN   Name=FOLR4; Synonyms=JUNO;
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-KW.
//
ID   JTB_HUMAN               Reviewed;         146 AA.
AC   O76095; O95442; Q6IB19; Q9P0Q4;
DE   RecName: Full=Protein JTB;
DE   AltName: Full=Jumping translocation breakpoint protein;
DE   AltName: Full=Prostate androgen-regulated protein;
DE            Short=PAR protein;
DE   Flags: Precursor;
GN   Name=JTB; ORFNames=HSPC222;
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
//
ID   JUN_HUMAN               Reviewed;         331 AA.
AC   P05412; Q96G93;
DE   RecName: Full=Transcription factor AP-1;
DE   AltName: Full=Activator protein 1;
DE            Short=AP1;
DE   AltName: Full=Proto-oncogene c-Jun;
DE   AltName: Full=V-jun avian sarcoma virus 17 oncogene homolog;
DE   AltName: Full=p39;
GN   Name=JUN;
DR   GO; GO:0035497; F:cAMP response element binding; IDA:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IC:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0051365; P:cellular response to potassium ion starvation; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035026; P:leading edge cell differentiation; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0051899; P:membrane depolarization; IEA:Ensembl.
DR   GO; GO:0001774; P:microglial cell activation; IEA:Ensembl.
DR   GO; GO:0030224; P:monocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045657; P:positive regulation of monocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   K0020_HUMAN             Reviewed;         648 AA.
AC   Q15397; A8K804; Q547G7; Q5SZY9; Q6IB47; Q96B27; Q96L78; Q96L79;
AC   Q96L80;
DE   RecName: Full=Pumilio domain-containing protein KIAA0020;
DE   AltName: Full=HBV X-transactivated gene 5 protein;
DE   AltName: Full=HBV XAg-transactivated protein 5;
DE   AltName: Full=Minor histocompatibility antigen HA-8;
DE            Short=HLA-HA8;
GN   Name=KIAA0020; Synonyms=XTP5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   K0087_HUMAN             Reviewed;         138 AA.
AC   Q14695; A1A524; Q75MW1;
DE   RecName: Full=Uncharacterized protein KIAA0087;
GN   Name=KIAA0087; ORFNames=HA1002;
//
ID   K0100_HUMAN             Reviewed;        2235 AA.
AC   Q14667; A6NCX3; Q3SYN5; Q49A07; Q5H9T4; Q6WG74; Q6ZP51; Q96HH8;
DE   RecName: Full=UPF0378 protein KIAA0100;
DE   AltName: Full=Antigen MLAA-22;
DE   AltName: Full=Breast cancer-overexpressed gene 1 protein;
DE   Flags: Precursor;
GN   Name=KIAA0100; Synonyms=BCOX1;
//
ID   K0040_HUMAN             Reviewed;         153 AA.
AC   Q15053; A8K9H6; Q2NKQ0;
DE   RecName: Full=Uncharacterized protein KIAA0040;
GN   Name=KIAA0040;
//
ID   K0195_HUMAN             Reviewed;        1356 AA.
AC   Q12767; O75536; Q86XF1;
DE   RecName: Full=Uncharacterized protein KIAA0195;
DE   AltName: Full=Transmembrane protein 94;
GN   Name=KIAA0195; Synonyms=TMEM94;
//
ID   K0125_HUMAN             Reviewed;         134 AA.
AC   Q9NZY2; C9J8W9;
DE   RecName: Full=Putative uncharacterized protein KIAA0125;
GN   Name=KIAA0125; Synonyms=C14orf110, FAM30A; ORFNames=HSPC053;
//
ID   K0232_HUMAN             Reviewed;        1395 AA.
AC   Q92628; A7E2D2;
DE   RecName: Full=Uncharacterized protein KIAA0232;
GN   Name=KIAA0232;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   K0319_HUMAN             Reviewed;        1072 AA.
AC   Q5VV43; A7MD37; B2RTU7; B4DHA7; B4DK75; B7ZML3; F5H123; Q9UJC8;
AC   Q9Y4G7;
DE   RecName: Full=Dyslexia-associated protein KIAA0319;
DE   Flags: Precursor;
GN   Name=KIAA0319;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:2000171; P:negative regulation of dendrite development; IGI:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IGI:UniProtKB.
//
ID   K0247_HUMAN             Reviewed;         303 AA.
AC   Q92537;
DE   RecName: Full=Uncharacterized protein KIAA0247;
DE   Flags: Precursor;
GN   Name=KIAA0247;
//
ID   K0513_HUMAN             Reviewed;         411 AA.
AC   O60268; B4DSS5; D3DUM2; Q8N6G0;
DE   RecName: Full=Uncharacterized protein KIAA0513;
GN   Name=KIAA0513;
//
ID   K0355_HUMAN             Reviewed;        1070 AA.
AC   O15063; Q2M3W4;
DE   RecName: Full=Uncharacterized protein KIAA0355;
GN   Name=KIAA0355;
//
ID   K0408_HUMAN             Reviewed;         694 AA.
AC   Q6ZU52; B3KRE5; E1P573; O43158; Q5TF20; Q7L2M2;
DE   RecName: Full=Uncharacterized protein KIAA0408;
GN   Name=KIAA0408;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   K0754_HUMAN             Reviewed;        1291 AA.
AC   O94854; E9PMC2; Q6ZSB2;
DE   RecName: Full=Uncharacterized protein KIAA0754;
GN   Name=KIAA0754;
//
ID   K0825_HUMAN             Reviewed;        1275 AA.
AC   Q8IV33; O94914; Q6ZNN2;
DE   RecName: Full=Uncharacterized protein KIAA0825;
GN   Name=KIAA0825; Synonyms=C5orf36;
//
ID   K0556_HUMAN             Reviewed;        1618 AA.
AC   O60303; A7E2C2;
DE   RecName: Full=Uncharacterized protein KIAA0556;
GN   Name=KIAA0556;
//
ID   K0753_HUMAN             Reviewed;         967 AA.
AC   Q2KHM9; A8KA11; B7Z479; O94853; Q05D97; Q2KHN0; Q9UG45;
DE   RecName: Full=Uncharacterized protein KIAA0753;
GN   Name=KIAA0753;
//
ID   K0907_HUMAN             Reviewed;         614 AA.
AC   Q7Z7F0; O94981; Q7L7Q2; Q7Z7E9; Q8TBQ0;
DE   RecName: Full=UPF0469 protein KIAA0907;
GN   Name=KIAA0907; Synonyms=BLOM7;
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
//
ID   K0930_HUMAN             Reviewed;         404 AA.
AC   Q6ICG6; B0QY17; B0QY19; B3KT48; Q6ZVE5; Q7Z6K9; Q8IZ76; Q9Y2E2;
DE   RecName: Full=Uncharacterized protein KIAA0930;
GN   Name=KIAA0930; Synonyms=C22orf9;
//
ID   K0895_HUMAN             Reviewed;         520 AA.
AC   Q8NCT3; B4DF35; B7ZLT4; B9EGB9; O94969; Q0VGC1; Q7Z4L2;
DE   RecName: Full=Uncharacterized protein KIAA0895;
GN   Name=KIAA0895;
//
ID   K0947_HUMAN             Reviewed;        2266 AA.
AC   Q9Y2F5; Q68DE1; Q6ZT40; Q7L587; Q7Z3A9; Q9NTH9;
DE   RecName: Full=Uncharacterized protein KIAA0947;
GN   Name=KIAA0947;
//
ID   K102L_HUMAN             Reviewed;         190 AA.
AC   P59773; H3BM78;
DE   RecName: Full=UPF0258 protein KIAA1024-like;
GN   Name=KIAA1024L;
//
ID   K1045_HUMAN             Reviewed;         400 AA.
AC   Q9UPV7; B7Z253; Q58FE9; Q5T662;
DE   RecName: Full=Protein KIAA1045;
GN   Name=KIAA1045;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   K1107_HUMAN             Reviewed;        1409 AA.
AC   Q9UPP5; O14767; Q8N3X7;
DE   RecName: Full=Uncharacterized protein KIAA1107;
GN   Name=KIAA1107;
//
ID   K1143_HUMAN             Reviewed;         154 AA.
AC   Q96AT1; A8K0I4; Q96HJ8; Q9ULS7;
DE   RecName: Full=Uncharacterized protein KIAA1143;
GN   Name=KIAA1143;
//
ID   K1024_HUMAN             Reviewed;         916 AA.
AC   Q9UPX6; A7MD43;
DE   RecName: Full=UPF0258 protein KIAA1024;
GN   Name=KIAA1024;
//
ID   K1211_HUMAN             Reviewed;        1233 AA.
AC   Q6ZU35; Q9NTE2; Q9NTP8; Q9ULK9;
DE   RecName: Full=Uncharacterized protein KIAA1211;
GN   Name=KIAA1211;
//
ID   K1109_HUMAN             Reviewed;        5005 AA.
AC   Q2LD37; Q4W598; Q5CZA9; Q6ZS70; Q6ZV75; Q86XA5; Q8WVD8; Q9H742;
AC   Q9NT48; Q9NTC3; Q9NTI4; Q9P2H6; Q9UPP3;
DE   RecName: Full=Uncharacterized protein KIAA1109;
DE   AltName: Full=Fragile site-associated protein;
GN   Name=KIAA1109; Synonyms=FSA, KIAA1371;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:BHF-UCL.
DR   GO; GO:0030856; P:regulation of epithelial cell differentiation; NAS:BHF-UCL.
//
ID   K1257_HUMAN             Reviewed;         409 AA.
AC   Q9ULG3; Q8IXY7; Q8N5T4;
DE   RecName: Full=Uncharacterized protein KIAA1257;
GN   Name=KIAA1257;
//
ID   K1210_HUMAN             Reviewed;        1709 AA.
AC   Q9ULL0; B7ZCI8; Q5JPN4;
DE   RecName: Full=Uncharacterized protein KIAA1210;
GN   Name=KIAA1210;
//
ID   K1161_HUMAN             Reviewed;         714 AA.
AC   Q6NSJ0; Q5T587; Q5T588; Q9ULQ9;
DE   RecName: Full=Uncharacterized family 31 glucosidase KIAA1161;
DE            EC=3.2.1.-;
GN   Name=KIAA1161;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
//
ID   K1328_HUMAN             Reviewed;         577 AA.
AC   Q86T90; Q05DL0; Q49AG6; Q9P2L8;
DE   RecName: Full=Uncharacterized protein KIAA1328;
GN   Name=KIAA1328;
//
ID   K1324_HUMAN             Reviewed;        1013 AA.
AC   Q6UXG2; Q08AE6; Q5T5C9; Q5T5D0; Q5T5D1; Q9P2M2;
DE   RecName: Full=UPF0577 protein KIAA1324;
DE   AltName: Full=Estrogen-induced gene 121 protein;
DE   Flags: Precursor;
GN   Name=KIAA1324; Synonyms=EIG121; ORFNames=UNQ2426/PRO4985;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IMP:BHF-UCL.
DR   GO; GO:0016236; P:macroautophagy; IMP:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:2000786; P:positive regulation of autophagic vacuole assembly; IMP:BHF-UCL.
DR   GO; GO:0044090; P:positive regulation of vacuole organization; IMP:BHF-UCL.
//
ID   K132L_HUMAN             Reviewed;        1029 AA.
AC   A8MWY0; A4D1C9; B4DJV3; Q17RI6; Q96DP2;
DE   RecName: Full=UPF0577 protein KIAA1324-like;
DE   AltName: Full=Estrogen-induced gene 121-like protein;
DE            Short=hEIG121L;
DE   Flags: Precursor;
GN   Name=KIAA1324L; Synonyms=EIG121L;
//
ID   K121L_HUMAN             Reviewed;         962 AA.
AC   Q6NV74;
DE   RecName: Full=Uncharacterized protein KIAA1211-like;
GN   Name=KIAA1211L; Synonyms=C2orf55;
//
ID   K1377_HUMAN             Reviewed;        1117 AA.
AC   Q9P2H0; Q4G0U6;
DE   RecName: Full=Uncharacterized protein KIAA1377;
GN   Name=KIAA1377;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   K1407_HUMAN             Reviewed;         936 AA.
AC   Q8NCU4; Q9P2E0;
DE   RecName: Full=Coiled-coil domain-containing protein KIAA1407;
GN   Name=KIAA1407;
//
ID   K1430_HUMAN             Reviewed;         532 AA.
AC   Q9P2B7; B3KRP7; D3DP60; Q05CU1; Q4W5M4; Q8N6E7; Q9UF45;
DE   RecName: Full=UPF0501 protein KIAA1430;
GN   Name=KIAA1430;
//
ID   K1456_HUMAN             Reviewed;         454 AA.
AC   Q9P272; Q96AW6;
DE   RecName: Full=Putative methyltransferase KIAA1456;
DE            EC=2.1.1.-;
GN   Name=KIAA1456; Synonyms=C8orf79;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   K1467_HUMAN             Reviewed;         622 AA.
AC   A2RU67; Q49AF2; Q5CZ81; Q6ZUV7; Q9P261;
DE   RecName: Full=Uncharacterized protein KIAA1467;
GN   Name=KIAA1467;
//
ID   K1468_HUMAN             Reviewed;        1216 AA.
AC   Q9P260;
DE   RecName: Full=LisH domain and HEAT repeat-containing protein KIAA1468;
GN   Name=KIAA1468;
//
ID   K1522_HUMAN             Reviewed;        1035 AA.
AC   Q9P206; B4DQU8; B5MDY0; C9JH84; Q8TCQ0;
DE   RecName: Full=Uncharacterized protein KIAA1522;
GN   Name=KIAA1522;
//
ID   K154L_HUMAN             Reviewed;        1849 AA.
AC   Q6ZVL6; B0QYU0;
DE   RecName: Full=UPF0606 protein KIAA1549L;
GN   Name=KIAA1549L; Synonyms=C11orf41, C11orf69;
//
ID   K1551_HUMAN             Reviewed;        1747 AA.
AC   Q9HCM1; B2RTU5; Q4KN17; Q9NVL6; Q9NWP9;
DE   RecName: Full=Uncharacterized protein KIAA1551;
GN   Name=KIAA1551; Synonyms=C12orf35;
//
ID   K1549_HUMAN             Reviewed;        1950 AA.
AC   Q9HCM3; B6HY55; B6HY56; B6HY58; B6HY60; B6HY61; B6HY62; B6HY63;
AC   B6HY64; B6HY65; B6HY66; Q5BJD6; Q8IY15; Q9H0M3;
DE   RecName: Full=UPF0606 protein KIAA1549;
GN   Name=KIAA1549;
//
ID   K1586_HUMAN             Reviewed;         787 AA.
AC   Q9HCI6; A8K4M3; Q8IW25;
DE   RecName: Full=Uncharacterized protein KIAA1586;
GN   Name=KIAA1586;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   K1644_HUMAN             Reviewed;         199 AA.
AC   Q3SXP7; A6NHP0; A9Z1Z0; Q3SXP8; Q5JZ71; Q9BYB5;
DE   RecName: Full=Uncharacterized protein KIAA1644;
DE   Flags: Precursor;
GN   Name=KIAA1644;
//
ID   K1654_HUMAN             Reviewed;          83 AA.
AC   Q9BYA6;
DE   RecName: Full=Putative uncharacterized protein KIAA1654;
GN   Name=KIAA1654;
//
ID   K1614_HUMAN             Reviewed;        1190 AA.
AC   Q5VZ46; Q5VZ45; Q9HCF8;
DE   RecName: Full=Uncharacterized protein KIAA1614;
GN   Name=KIAA1614;
//
ID   K1671_HUMAN             Reviewed;        1806 AA.
AC   Q9BY89; B0QYF2; B7ZW08; Q5THZ5;
DE   RecName: Full=Uncharacterized protein KIAA1671;
GN   Name=KIAA1671;
//
ID   K1683_HUMAN             Reviewed;        1180 AA.
AC   Q9H0B3; B4DYH2; E9PDE0; E9PH54; Q2KHR5; Q8N4G8; Q96M14; Q9C0I0;
DE   RecName: Full=Uncharacterized protein KIAA1683;
GN   Name=KIAA1683;
//
ID   K1731_HUMAN             Reviewed;        2601 AA.
AC   Q9C0D2; C9J5H9; C9JQY8; Q8N7L4; Q8N919; Q8N9B0; Q96LT8;
DE   RecName: Full=Centrosomal protein KIAA1731;
GN   Name=KIAA1731;
//
ID   K1751_HUMAN             Reviewed;         762 AA.
AC   Q9C0B2; A4VCI2; Q5T2D9; Q5T2E0; Q6ZSJ4;
DE   RecName: Full=Uncharacterized protein KIAA1751;
GN   Name=KIAA1751;
//
ID   K1920_HUMAN             Reviewed;         444 AA.
AC   Q96PW8;
DE   RecName: Full=Putative uncharacterized protein KIAA1920;
GN   Name=CSPG4P5; Synonyms=KIAA1920;
//
ID   K1755_HUMAN             Reviewed;        1200 AA.
AC   Q5JYT7; Q9C0A8;
DE   RecName: Full=Uncharacterized protein KIAA1755;
GN   Name=KIAA1755;
//
ID   K1875_HUMAN             Reviewed;        1622 AA.
AC   A6NE52; Q96JF2;
DE   RecName: Full=WD repeat-containing protein KIAA1875;
GN   Name=KIAA1875;
//
ID   K1908_HUMAN             Reviewed;         264 AA.
AC   Q96PY0; Q8NAR8; Q8NBC0;
DE   RecName: Full=Putative uncharacterized protein PSMG3-AS1;
DE   AltName: Full=PSMG3 antisense RNA 1;
GN   Name=PSMG3-AS1; Synonyms=KIAA1908;
//
ID   K1958_HUMAN             Reviewed;         716 AA.
AC   Q8N8K9; B7ZKW6; Q2M336; Q5T252; Q8TF43; Q96N02;
DE   RecName: Full=Uncharacterized protein KIAA1958;
GN   Name=KIAA1958;
//
ID   K1841_HUMAN             Reviewed;         718 AA.
AC   Q6NSI8; Q49AF0; Q6ZND0; Q96JI6;
DE   RecName: Full=Uncharacterized protein KIAA1841;
GN   Name=KIAA1841;
//
ID   K1C10_HUMAN             Reviewed;         584 AA.
AC   P13645; Q14664; Q8N175;
DE   RecName: Full=Keratin, type I cytoskeletal 10;
DE   AltName: Full=Cytokeratin-10;
DE            Short=CK-10;
DE   AltName: Full=Keratin-10;
DE            Short=K10;
GN   Name=KRT10; Synonyms=KPP;
DR   GO; GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.
//
ID   K1C12_HUMAN             Reviewed;         494 AA.
AC   Q99456; B2R9E0;
DE   RecName: Full=Keratin, type I cytoskeletal 12;
DE   AltName: Full=Cytokeratin-12;
DE            Short=CK-12;
DE   AltName: Full=Keratin-12;
DE            Short=K12;
GN   Name=KRT12;
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   K1C13_HUMAN             Reviewed;         458 AA.
AC   P13646; Q53G54; Q6AZK5; Q8N240;
DE   RecName: Full=Keratin, type I cytoskeletal 13;
DE   AltName: Full=Cytokeratin-13;
DE            Short=CK-13;
DE   AltName: Full=Keratin-13;
DE            Short=K13;
GN   Name=KRT13;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0043587; P:tongue morphogenesis; IEA:Ensembl.
//
ID   K1C14_HUMAN             Reviewed;         472 AA.
AC   P02533; Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4;
DE   RecName: Full=Keratin, type I cytoskeletal 14;
DE   AltName: Full=Cytokeratin-14;
DE            Short=CK-14;
DE   AltName: Full=Keratin-14;
DE            Short=K14;
GN   Name=KRT14;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
DR   GO; GO:0045110; P:intermediate filament bundle assembly; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
//
ID   K1C15_HUMAN             Reviewed;         456 AA.
AC   P19012; B3KQY1; Q53XV8; Q9BUG4;
DE   RecName: Full=Keratin, type I cytoskeletal 15;
DE   AltName: Full=Cytokeratin-15;
DE            Short=CK-15;
DE   AltName: Full=Keratin-15;
DE            Short=K15;
GN   Name=KRT15; Synonyms=KRTB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   K1C16_HUMAN             Reviewed;         473 AA.
AC   P08779; A8K488; P30654; Q16402; Q9UBG8;
DE   RecName: Full=Keratin, type I cytoskeletal 16;
DE   AltName: Full=Cytokeratin-16;
DE            Short=CK-16;
DE   AltName: Full=Keratin-16;
DE            Short=K16;
GN   Name=KRT16; Synonyms=KRT16A;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:Ensembl.
//
ID   K1C17_HUMAN             Reviewed;         432 AA.
AC   Q04695; A5Z1M9; A5Z1N0; A5Z1N1; A5Z1N2; A6NDV6; A6NKQ2; Q6IP98;
AC   Q8N1P6;
DE   RecName: Full=Keratin, type I cytoskeletal 17;
DE   AltName: Full=39.1;
DE   AltName: Full=Cytokeratin-17;
DE            Short=CK-17;
DE   AltName: Full=Keratin-17;
DE            Short=K17;
GN   Name=KRT17;
DR   GO; GO:0042289; F:MHC class II protein binding; IPI:UniProtKB.
DR   GO; GO:0032395; F:MHC class II receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR   GO; GO:0031424; P:keratinization; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0051798; P:positive regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
//
ID   K1C18_HUMAN             Reviewed;         430 AA.
AC   P05783; Q53G38; Q5U0N8; Q9BW26;
DE   RecName: Full=Keratin, type I cytoskeletal 18;
DE   AltName: Full=Cell proliferation-inducing gene 46 protein;
DE   AltName: Full=Cytokeratin-18;
DE            Short=CK-18;
DE   AltName: Full=Keratin-18;
DE            Short=K18;
GN   Name=KRT18; Synonyms=CYK18; ORFNames=PIG46;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043000; P:Golgi to plasma membrane CFTR protein transport; IDA:UniProtKB.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   K1C19_HUMAN             Reviewed;         400 AA.
AC   P08727; B2R874; Q5XG83; Q6NW33; Q7L5M9; Q96A53; Q96FV1; Q9BYF9;
AC   Q9P1Y4;
DE   RecName: Full=Keratin, type I cytoskeletal 19;
DE   AltName: Full=Cytokeratin-19;
DE            Short=CK-19;
DE   AltName: Full=Keratin-19;
DE            Short=K19;
GN   Name=KRT19;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008307; F:structural constituent of muscle; IDA:UniProtKB.
DR   GO; GO:0060706; P:cell differentiation involved in embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEP:UniProtKB.
DR   GO; GO:0045214; P:sarcomere organization; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   K1C20_HUMAN             Reviewed;         424 AA.
AC   P35900; B2R6W7;
DE   RecName: Full=Keratin, type I cytoskeletal 20;
DE   AltName: Full=Cytokeratin-20;
DE            Short=CK-20;
DE   AltName: Full=Keratin-20;
DE            Short=K20;
DE   AltName: Full=Protein IT;
GN   Name=KRT20;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0033554; P:cellular response to stress; IEA:Ensembl.
DR   GO; GO:0045109; P:intermediate filament organization; IMP:UniProtKB.
DR   GO; GO:0050708; P:regulation of protein secretion; IEA:Ensembl.
//
ID   K1C23_HUMAN             Reviewed;         422 AA.
AC   Q9C075; A8K084; Q9NUR6;
DE   RecName: Full=Keratin, type I cytoskeletal 23;
DE   AltName: Full=Cytokeratin-23;
DE            Short=CK-23;
DE   AltName: Full=Keratin-23;
DE            Short=K23;
GN   Name=KRT23;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K1C24_HUMAN             Reviewed;         525 AA.
AC   Q2M2I5; Q9NXG7;
DE   RecName: Full=Keratin, type I cytoskeletal 24;
DE   AltName: Full=Cytokeratin-24;
DE            Short=CK-24;
DE   AltName: Full=Keratin-24;
DE            Short=K24;
DE   AltName: Full=Type I keratin-24;
GN   Name=KRT24; Synonyms=KA24;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K1C25_HUMAN             Reviewed;         450 AA.
AC   Q7Z3Z0;
DE   RecName: Full=Keratin, type I cytoskeletal 25;
DE   AltName: Full=Cytokeratin-25;
DE            Short=CK-25;
DE   AltName: Full=Keratin-25;
DE            Short=K25;
DE   AltName: Full=Keratin-25A;
DE            Short=K25A;
DE   AltName: Full=Type I inner root sheath-specific keratin-K25irs1;
GN   Name=KRT25; Synonyms=KRT25A;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
//
ID   K1C26_HUMAN             Reviewed;         468 AA.
AC   Q7Z3Y9; A2RUL2; B2RNH8;
DE   RecName: Full=Keratin, type I cytoskeletal 26;
DE   AltName: Full=Cytokeratin-26;
DE            Short=CK-26;
DE   AltName: Full=Keratin-25B;
DE            Short=K25B;
DE   AltName: Full=Keratin-26;
DE            Short=K26;
DE   AltName: Full=Type I inner root sheath-specific keratin-K25irs2;
GN   Name=KRT26; Synonyms=KRT25B;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K1C27_HUMAN             Reviewed;         459 AA.
AC   Q7Z3Y8;
DE   RecName: Full=Keratin, type I cytoskeletal 27;
DE   AltName: Full=Cytokeratin-27;
DE            Short=CK-27;
DE   AltName: Full=Keratin-25C;
DE            Short=K25C;
DE   AltName: Full=Keratin-27;
DE            Short=K27;
DE   AltName: Full=Type I inner root sheath-specific keratin-K25irs3;
GN   Name=KRT27; Synonyms=KRT25C;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
//
ID   K1C28_HUMAN             Reviewed;         464 AA.
AC   Q7Z3Y7; Q6ZP84;
DE   RecName: Full=Keratin, type I cytoskeletal 28;
DE   AltName: Full=Cytokeratin-28;
DE            Short=CK-28;
DE   AltName: Full=Keratin-25D;
DE            Short=K25D;
DE   AltName: Full=Keratin-28;
DE            Short=K28;
DE   AltName: Full=Type I inner root sheath-specific keratin-K25irs4;
GN   Name=KRT28; Synonyms=KRT25D;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K1C39_HUMAN             Reviewed;         491 AA.
AC   Q6A163; B2RXK6; Q6IFU6;
DE   RecName: Full=Keratin, type I cytoskeletal 39;
DE   AltName: Full=Cytokeratin-39;
DE            Short=CK-39;
DE   AltName: Full=Keratin-39;
DE            Short=K39;
DE   AltName: Full=Type I hair keratin Ka35;
GN   Name=KRT39; Synonyms=KA35;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K1C40_HUMAN             Reviewed;         431 AA.
AC   Q6A162; Q6IFU5;
DE   RecName: Full=Keratin, type I cytoskeletal 40;
DE   AltName: Full=Cytokeratin-40;
DE            Short=CK-40;
DE   AltName: Full=Keratin-40;
DE            Short=K40;
DE   AltName: Full=Type I hair keratin Ka36;
GN   Name=KRT40; Synonyms=KA36;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K1C9_HUMAN              Reviewed;         623 AA.
AC   P35527; O00109; Q0IJ47; Q14665;
DE   RecName: Full=Keratin, type I cytoskeletal 9;
DE   AltName: Full=Cytokeratin-9;
DE            Short=CK-9;
DE   AltName: Full=Keratin-9;
DE            Short=K9;
GN   Name=KRT9;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0045109; P:intermediate filament organization; IMP:UniProtKB.
DR   GO; GO:0043588; P:skin development; IDA:UniProtKB.
//
ID   K1H1_HUMAN              Reviewed;         416 AA.
AC   Q15323; Q9UE12;
DE   RecName: Full=Keratin, type I cuticular Ha1;
DE   AltName: Full=Hair keratin, type I Ha1;
DE   AltName: Full=Keratin-31;
DE            Short=K31;
GN   Name=KRT31; Synonyms=HHA1, HKA1, KRTHA1;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   K1H2_HUMAN              Reviewed;         448 AA.
AC   Q14532;
DE   RecName: Full=Keratin, type I cuticular Ha2;
DE   AltName: Full=Hair keratin, type I Ha2;
DE   AltName: Full=Keratin-32;
DE            Short=K32;
GN   Name=KRT32; Synonyms=HHA2, HKA2, KRTHA2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   K2012_HUMAN             Reviewed;         553 AA.
AC   Q0VF49; Q8IVF9;
DE   RecName: Full=Uncharacterized protein KIAA2012;
GN   Name=KIAA2012;
//
ID   K2013_HUMAN             Reviewed;         634 AA.
AC   Q8IYS2; Q5JXC1; Q8IVF8; Q8NDI7; Q9BSY1;
DE   RecName: Full=Uncharacterized protein KIAA2013;
DE   Flags: Precursor;
GN   Name=KIAA2013;
//
ID   K2018_HUMAN             Reviewed;        2245 AA.
AC   Q68DE3; Q7Z3L9; Q8IVF3; Q9H8T4;
DE   RecName: Full=Basic helix-loop-helix domain-containing protein KIAA2018;
GN   Name=KIAA2018;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IEA:InterPro.
//
ID   K2022_HUMAN             Reviewed;        1516 AA.
AC   Q5QGS0; A7YY87; Q5JUX9; Q8IVE9;
DE   RecName: Full=Protein KIAA2022;
GN   Name=KIAA2022;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IBA:RefGenome.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IBA:RefGenome.
DR   GO; GO:0006287; P:base-excision repair, gap-filling; IBA:RefGenome.
DR   GO; GO:0045004; P:DNA replication proofreading; IBA:RefGenome.
DR   GO; GO:0043137; P:DNA replication, removal of RNA primer; IBA:RefGenome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IBA:GOC.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IBA:RefGenome.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IBA:RefGenome.
//
ID   K2026_HUMAN             Reviewed;        2103 AA.
AC   Q5HYC2; A8MTP2; B9EGW7; Q4VXA2; Q8IVE5;
DE   RecName: Full=Uncharacterized protein KIAA2026;
GN   Name=KIAA2026;
//
ID   K226L_HUMAN             Reviewed;         662 AA.
AC   Q9H714; A8XR19; B3KS87; Q5W051; Q5W053; Q6PJ74; Q6PK94; Q86XH7;
AC   Q8N5J6;
DE   RecName: Full=Uncharacterized protein KIAA0226-like;
GN   Name=KIAA0226L; Synonyms=C13orf18;
//
ID   K22E_HUMAN              Reviewed;         639 AA.
AC   P35908; Q4VAQ2;
DE   RecName: Full=Keratin, type II cytoskeletal 2 epidermal;
DE   AltName: Full=Cytokeratin-2e;
DE            Short=CK-2e;
DE   AltName: Full=Epithelial keratin-2e;
DE   AltName: Full=Keratin-2 epidermis;
DE   AltName: Full=Keratin-2e;
DE            Short=K2e;
DE   AltName: Full=Type-II keratin Kb2;
GN   Name=KRT2; Synonyms=KRT2A, KRT2E;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0031424; P:keratinization; IDA:UniProtKB.
DR   GO; GO:0032980; P:keratinocyte activation; IDA:UniProtKB.
DR   GO; GO:0051546; P:keratinocyte migration; IDA:UniProtKB.
DR   GO; GO:0043616; P:keratinocyte proliferation; IDA:UniProtKB.
//
ID   K22O_HUMAN              Reviewed;         638 AA.
AC   Q01546; B4DRR3; Q7Z795;
DE   RecName: Full=Keratin, type II cytoskeletal 2 oral;
DE   AltName: Full=Cytokeratin-2P;
DE            Short=CK-2P;
DE            Short=K2P;
DE   AltName: Full=Keratin-76;
DE            Short=K76;
DE   AltName: Full=Type-II keratin Kb9;
GN   Name=KRT76; Synonyms=KRT2B, KRT2P;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
//
ID   K2C1B_HUMAN             Reviewed;         578 AA.
AC   Q7Z794; Q7RTS8;
DE   RecName: Full=Keratin, type II cytoskeletal 1b;
DE   AltName: Full=Cytokeratin-1B;
DE            Short=CK-1B;
DE   AltName: Full=Keratin-77;
DE            Short=K77;
DE   AltName: Full=Type-II keratin Kb39;
GN   Name=KRT77; Synonyms=KRT1B;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C1_HUMAN              Reviewed;         644 AA.
AC   P04264; B2RA01; Q14720; Q6GSJ0; Q9H298;
DE   RecName: Full=Keratin, type II cytoskeletal 1;
DE   AltName: Full=67 kDa cytokeratin;
DE   AltName: Full=Cytokeratin-1;
DE            Short=CK-1;
DE   AltName: Full=Hair alpha protein;
DE   AltName: Full=Keratin-1;
DE            Short=K1;
DE   AltName: Full=Type-II keratin Kb1;
GN   Name=KRT1; Synonyms=KRTA;
DR   GO; GO:0030246; F:carbohydrate binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0001867; P:complement activation, lectin pathway; IPI:UniProtKB.
DR   GO; GO:0042730; P:fibrinolysis; NAS:UniProtKB.
DR   GO; GO:0045765; P:regulation of angiogenesis; NAS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; NAS:UniProtKB.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   K2C3_HUMAN              Reviewed;         628 AA.
AC   P12035; A6NIS2; Q701L8;
DE   RecName: Full=Keratin, type II cytoskeletal 3;
DE   AltName: Full=65 kDa cytokeratin;
DE   AltName: Full=Cytokeratin-3;
DE            Short=CK-3;
DE   AltName: Full=Keratin-3;
DE            Short=K3;
DE   AltName: Full=Type-II keratin Kb3;
GN   Name=KRT3;
DR   GO; GO:0005198; F:structural molecule activity; IMP:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IMP:UniProtKB.
//
ID   K2C4_HUMAN              Reviewed;         534 AA.
AC   P19013; F8VS64; Q6GTR8; Q96LA7; Q9BTL1;
DE   RecName: Full=Keratin, type II cytoskeletal 4;
DE   AltName: Full=Cytokeratin-4;
DE            Short=CK-4;
DE   AltName: Full=Keratin-4;
DE            Short=K4;
DE   AltName: Full=Type-II keratin Kb4;
GN   Name=KRT4; Synonyms=CYK4;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.
//
ID   K2C5_HUMAN              Reviewed;         590 AA.
AC   P13647; Q6PI71; Q6UBJ0; Q8TA91;
DE   RecName: Full=Keratin, type II cytoskeletal 5;
DE   AltName: Full=58 kDa cytokeratin;
DE   AltName: Full=Cytokeratin-5;
DE            Short=CK-5;
DE   AltName: Full=Keratin-5;
DE            Short=K5;
DE   AltName: Full=Type-II keratin Kb5;
GN   Name=KRT5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
//
ID   K2C6A_HUMAN             Reviewed;         564 AA.
AC   P02538; A4QPC1; P48667; Q08AR4; Q6NT67; Q96CL4;
DE   RecName: Full=Keratin, type II cytoskeletal 6A;
DE   AltName: Full=Cytokeratin-6A;
DE            Short=CK-6A;
DE   AltName: Full=Cytokeratin-6D;
DE            Short=CK-6D;
DE   AltName: Full=Keratin-6A;
DE            Short=K6A;
DE   AltName: Full=Type-II keratin Kb6;
DE   AltName: Allergen=Hom s 5;
GN   Name=KRT6A; Synonyms=K6A, KRT6D;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0007398; P:ectoderm development; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; NAS:UniProtKB.
//
ID   K2C6B_HUMAN             Reviewed;         564 AA.
AC   P04259; P48669;
DE   RecName: Full=Keratin, type II cytoskeletal 6B;
DE   AltName: Full=Cytokeratin-6B;
DE            Short=CK-6B;
DE   AltName: Full=Keratin-6B;
DE            Short=K6B;
DE   AltName: Full=Type-II keratin Kb10;
GN   Name=KRT6B; Synonyms=K6B, KRTL1;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0007398; P:ectoderm development; TAS:ProtInc.
//
ID   K2C6C_HUMAN             Reviewed;         564 AA.
AC   P48668; A1L4L5; P48666; Q2TAZ9; Q7RTN9;
DE   RecName: Full=Keratin, type II cytoskeletal 6C;
DE   AltName: Full=Cytokeratin-6C;
DE            Short=CK-6C;
DE   AltName: Full=Cytokeratin-6E;
DE            Short=CK-6E;
DE   AltName: Full=Keratin K6h;
DE   AltName: Full=Keratin-6C;
DE            Short=K6C;
DE   AltName: Full=Type-II keratin Kb12;
GN   Name=KRT6C; Synonyms=KRT6E;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C71_HUMAN             Reviewed;         523 AA.
AC   Q3SY84; B3KVC1; Q3SY85; Q96DU2;
DE   RecName: Full=Keratin, type II cytoskeletal 71;
DE   AltName: Full=Cytokeratin-71;
DE            Short=CK-71;
DE   AltName: Full=Keratin-71;
DE            Short=K71;
DE   AltName: Full=Type II inner root sheath-specific keratin-K6irs1;
DE            Short=Keratin 6 irs;
DE            Short=hK6irs;
DE            Short=hK6irs1;
DE   AltName: Full=Type-II keratin Kb34;
GN   Name=KRT71; Synonyms=K6IRS1, KB34, KRT6IRS1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
//
ID   K2C72_HUMAN             Reviewed;         511 AA.
AC   Q14CN4; B4DEI8; H9KV51; Q8NA87; Q8WWY9; Q8WWZ0;
DE   RecName: Full=Keratin, type II cytoskeletal 72;
DE   AltName: Full=Cytokeratin-72;
DE            Short=CK-72;
DE   AltName: Full=Keratin-72;
DE            Short=K72;
DE   AltName: Full=Type II inner root sheath-specific keratin-K6irs2;
DE   AltName: Full=Type-II keratin Kb35;
GN   Name=KRT72; Synonyms=K6IRS2, KB35, KRT6, KRT6IRS2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C73_HUMAN             Reviewed;         540 AA.
AC   Q86Y46; Q32MB2;
DE   RecName: Full=Keratin, type II cytoskeletal 73;
DE   AltName: Full=Cytokeratin-73;
DE            Short=CK-73;
DE   AltName: Full=Keratin-73;
DE            Short=K73;
DE   AltName: Full=Type II inner root sheath-specific keratin-K6irs3;
DE   AltName: Full=Type-II keratin Kb36;
GN   Name=KRT73; Synonyms=K6IRS3, KB36, KRT6IRS3;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C74_HUMAN             Reviewed;         529 AA.
AC   Q7RTS7; B5MD61; Q86Y45;
DE   RecName: Full=Keratin, type II cytoskeletal 74;
DE   AltName: Full=Cytokeratin-74;
DE            Short=CK-74;
DE   AltName: Full=Keratin-5c;
DE            Short=K5C;
DE   AltName: Full=Keratin-74;
DE            Short=K74;
DE   AltName: Full=Type II inner root sheath-specific keratin-K6irs4;
DE   AltName: Full=Type-II keratin Kb37;
GN   Name=KRT74; Synonyms=K6IRS4, KB37, KRT5C, KRT6IRS4;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C75_HUMAN             Reviewed;         551 AA.
AC   O95678; B4DQU4; Q9NSA9;
DE   RecName: Full=Keratin, type II cytoskeletal 75;
DE   AltName: Full=Cytokeratin-75;
DE            Short=CK-75;
DE   AltName: Full=Keratin-6 hair follicle;
DE            Short=hK6hf;
DE   AltName: Full=Keratin-75;
DE            Short=K75;
DE   AltName: Full=Type II keratin-K6hf;
DE   AltName: Full=Type-II keratin Kb18;
GN   Name=KRT75; Synonyms=K6HF, KB18;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
//
ID   K2C78_HUMAN             Reviewed;         520 AA.
AC   Q8N1N4; A8K4D6; Q5HYM7; Q7RTT2;
DE   RecName: Full=Keratin, type II cytoskeletal 78;
DE   AltName: Full=Cytokeratin-78;
DE            Short=CK-78;
DE   AltName: Full=Keratin-5b;
DE   AltName: Full=Keratin-78;
DE            Short=K78;
DE   AltName: Full=Type-II keratin Kb40;
GN   Name=KRT78; Synonyms=K5B, KB40;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C79_HUMAN             Reviewed;         535 AA.
AC   Q5XKE5; Q6P465; Q7Z793;
DE   RecName: Full=Keratin, type II cytoskeletal 79;
DE   AltName: Full=Cytokeratin-79;
DE            Short=CK-79;
DE   AltName: Full=Keratin-6-like;
DE            Short=Keratin-6L;
DE   AltName: Full=Keratin-79;
DE            Short=K79;
DE   AltName: Full=Type-II keratin Kb38;
GN   Name=KRT79; Synonyms=K6L, KB38, KRT6L;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C7_HUMAN              Reviewed;         469 AA.
AC   P08729; Q92676; Q9BUD8; Q9Y3R7;
DE   RecName: Full=Keratin, type II cytoskeletal 7;
DE   AltName: Full=Cytokeratin-7;
DE            Short=CK-7;
DE   AltName: Full=Keratin-7;
DE            Short=K7;
DE   AltName: Full=Sarcolectin;
DE   AltName: Full=Type-II keratin Kb7;
GN   Name=KRT7; Synonyms=SCL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   K2C80_HUMAN             Reviewed;         452 AA.
AC   Q6KB66; Q6P1A5; Q7Z3Q0;
DE   RecName: Full=Keratin, type II cytoskeletal 80;
DE   AltName: Full=Cytokeratin-80;
DE            Short=CK-80;
DE   AltName: Full=Keratin-80;
DE            Short=K80;
DE   AltName: Full=Type-II keratin Kb20;
GN   Name=KRT80; Synonyms=KB20;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   K2C8_HUMAN              Reviewed;         483 AA.
AC   P05787; A8K4H3; B0AZN5; F8VXB4; Q14099; Q14716; Q14717; Q53GJ0;
AC   Q6DHW5; Q6GMY0; Q6P4C7; Q96J60;
DE   RecName: Full=Keratin, type II cytoskeletal 8;
DE   AltName: Full=Cytokeratin-8;
DE            Short=CK-8;
DE   AltName: Full=Keratin-8;
DE            Short=K8;
DE   AltName: Full=Type-II keratin Kb8;
GN   Name=KRT8; Synonyms=CYK8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0060706; P:cell differentiation involved in embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0051599; P:response to hydrostatic pressure; IEA:Ensembl.
DR   GO; GO:0051707; P:response to other organism; IEA:Ensembl.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   K319L_HUMAN             Reviewed;        1049 AA.
AC   Q8IZA0; B1AN13; D3DPR8; O95010; Q6PJJ7; Q7L1C9; Q8N2B3; Q8NDA0;
AC   Q8WY39; Q8WYZ5; Q96IC3; Q96JJ0; Q9BUW6; Q9H7V0;
DE   RecName: Full=Dyslexia-associated protein KIAA0319-like protein;
GN   Name=KIAA0319L; Synonyms=KIAA1837; ORFNames=PP791;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   K6PF_HUMAN              Reviewed;         780 AA.
AC   P08237; J3KNX3; Q16814; Q16815; Q6ZTT1;
DE   RecName: Full=6-phosphofructokinase, muscle type;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphofructo-1-kinase isozyme A;
DE            Short=PFK-A;
DE            Short=Phosphofructokinase-M;
DE   AltName: Full=Phosphofructokinase 1;
DE   AltName: Full=Phosphohexokinase;
GN   Name=PFKM; Synonyms=PFKX;
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0070061; F:fructose binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:HGNC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:GOC.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IMP:UniProtKB.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IMP:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   K6PL_HUMAN              Reviewed;         780 AA.
AC   P17858; Q96A64; Q96IH4; Q9BR91;
DE   RecName: Full=6-phosphofructokinase, liver type;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphofructo-1-kinase isozyme B;
DE            Short=PFK-B;
DE   AltName: Full=Phosphofructokinase 1;
DE   AltName: Full=Phosphohexokinase;
GN   Name=PFKL;
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0070061; F:fructose binding; IDA:BHF-UCL.
DR   GO; GO:0070095; F:fructose-6-phosphate binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:GOC.
DR   GO; GO:0030388; P:fructose 1,6-bisphosphate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IDA:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IDA:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   K6PP_HUMAN              Reviewed;         784 AA.
AC   Q01813; B3KS15; Q5VSR7; Q5VSR8;
DE   RecName: Full=6-phosphofructokinase type C;
DE            EC=2.7.1.11;
DE   AltName: Full=6-phosphofructokinase, platelet type;
DE   AltName: Full=Phosphofructo-1-kinase isozyme C;
DE            Short=PFK-C;
DE   AltName: Full=Phosphofructokinase 1;
DE   AltName: Full=Phosphohexokinase;
GN   Name=PFKP; Synonyms=PFKF;
DR   GO; GO:0003872; F:6-phosphofructokinase activity; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; ISS:GOC.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   K895L_HUMAN             Reviewed;         471 AA.
AC   Q68EN5; A2VCS8; Q8N3H9; Q8NAQ5; Q96IE5;
DE   RecName: Full=Uncharacterized protein KIAA0895-like;
GN   Name=KIAA0895L;
//
ID   KAAG1_HUMAN             Reviewed;          84 AA.
AC   Q9UBP8;
DE   RecName: Full=Kidney-associated antigen 1;
DE   AltName: Full=RU2 antisense gene protein;
GN   Name=KAAG1; Synonyms=RU2AS;
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   KAD1_HUMAN              Reviewed;         194 AA.
AC   P00568; Q9BVK9; Q9UQC7;
DE   RecName: Full=Adenylate kinase isoenzyme 1;
DE            Short=AK 1;
DE            EC=2.7.4.3;
DE            EC=2.7.4.6;
DE   AltName: Full=ATP-AMP transphosphorylase 1;
DE   AltName: Full=ATP:AMP phosphotransferase;
DE   AltName: Full=Adenylate monophosphate kinase;
DE   AltName: Full=Myokinase;
GN   Name=AK1;
DR   GO; GO:0004017; F:adenylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:InterPro.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KAD2_HUMAN              Reviewed;         239 AA.
AC   P54819; A8K6L1; B4DHH7; B4DL64; Q16856; Q5EB54; Q5TIF7; Q8TCY2;
AC   Q8TCY3;
DE   RecName: Full=Adenylate kinase 2, mitochondrial;
DE            Short=AK 2;
DE            EC=2.7.4.3;
DE   AltName: Full=ATP-AMP transphosphorylase 2;
DE   AltName: Full=ATP:AMP phosphotransferase;
DE   AltName: Full=Adenylate monophosphate kinase;
DE   Contains:
DE     RecName: Full=Adenylate kinase 2, mitochondrial, N-terminally processed;
GN   Name=AK2; Synonyms=ADK2;
DR   GO; GO:0004017; F:adenylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006172; P:ADP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046033; P:AMP metabolic process; IEA:Ensembl.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0046060; P:dATP metabolic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:Ensembl.
DR   GO; GO:0097066; P:response to thyroid hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KAD3_HUMAN              Reviewed;         227 AA.
AC   Q9UIJ7; B4DP58; D3DRI1; E7ET30; Q5VYW6; Q9H576; Q9HC01; Q9NPB4;
DE   RecName: Full=GTP:AMP phosphotransferase AK3, mitochondrial;
DE            EC=2.7.4.10;
DE   AltName: Full=Adenylate kinase 3;
DE            Short=AK 3;
DE   AltName: Full=Adenylate kinase 3 alpha-like 1;
GN   Name=AK3; Synonyms=AK3L1, AK6, AKL3L;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046899; F:nucleoside triphosphate adenylate kinase activity; IDA:BHF-UCL.
DR   GO; GO:0046033; P:AMP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0046039; P:GTP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0046041; P:ITP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0046051; P:UTP metabolic process; IDA:BHF-UCL.
//
ID   KAD4_HUMAN              Reviewed;         223 AA.
AC   P27144; B2R927; D3DQ62; Q6IBH4; Q6NXQ5; Q8IUU9;
DE   RecName: Full=Adenylate kinase 4, mitochondrial;
DE            Short=AK 4;
DE            EC=2.7.4.10;
DE            EC=2.7.4.6;
DE   AltName: Full=Adenylate kinase 3-like;
DE   AltName: Full=GTP:AMP phosphotransferase AK4;
GN   Name=AK4; Synonyms=AK3, AK3L1;
DR   GO; GO:0004017; F:adenylate kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0046899; F:nucleoside triphosphate adenylate kinase activity; IDA:BHF-UCL.
DR   GO; GO:0046033; P:AMP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0046034; P:ATP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0046039; P:GTP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   KAD5_HUMAN              Reviewed;         562 AA.
AC   Q9Y6K8; Q5U622; Q6FH66; Q7Z4T5; Q86YS0; Q8N464; Q96EC9;
DE   RecName: Full=Adenylate kinase isoenzyme 5;
DE            Short=AK 5;
DE            EC=2.7.4.3;
DE            EC=2.7.4.6;
DE   AltName: Full=ATP-AMP transphosphorylase 5;
GN   Name=AK5;
DR   GO; GO:0004017; F:adenylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
DR   GO; GO:0006172; P:ADP biosynthetic process; TAS:ProtInc.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:InterPro.
DR   GO; GO:0006173; P:dADP biosynthetic process; TAS:ProtInc.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KAD6_HUMAN              Reviewed;         172 AA.
AC   Q9Y3D8; A8MSZ6; Q5F2S9;
DE   RecName: Full=Adenylate kinase isoenzyme 6;
DE            Short=AK6;
DE            EC=2.7.4.3;
DE   AltName: Full=Adrenal gland protein AD-004;
DE   AltName: Full=Coilin-interacting nuclear ATPase protein;
DE            Short=hCINAP;
DE   AltName: Full=Dual activity adenylate kinase/ATPase;
DE            Short=AK/ATPase;
GN   Name=AK6; Synonyms=CINAP; ORFNames=AD-004, CGI-137;
DR   GO; GO:0004017; F:adenylate kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046939; P:nucleotide phosphorylation; IDA:GOC.
//
ID   KAD7_HUMAN              Reviewed;         723 AA.
AC   Q96M32; Q8IYP6;
DE   RecName: Full=Adenylate kinase 7;
DE            Short=AK 7;
DE            EC=2.7.4.3;
DE            EC=2.7.4.6;
DE   AltName: Full=ATP-AMP transphosphorylase 7;
GN   Name=AK7;
DR   GO; GO:0004017; F:adenylate kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004127; F:cytidylate kinase activity; IDA:UniProtKB.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   KAD8_HUMAN              Reviewed;         479 AA.
AC   Q96MA6; A8K821; Q8N9W9;
DE   RecName: Full=Adenylate kinase 8;
DE            Short=AK 8;
DE            EC=2.7.4.3;
DE            EC=2.7.4.6;
DE   AltName: Full=ATP-AMP transphosphorylase 8;
GN   Name=AK8; Synonyms=C9orf98;
DR   GO; GO:0004017; F:adenylate kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004127; F:cytidylate kinase activity; IDA:UniProtKB.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
//
ID   KAD9_HUMAN              Reviewed;        1911 AA.
AC   Q5TCS8; A6NL75; B2RDJ0; B6ZDM7; Q3MIS4; Q5I0W8; Q6ZNF1; Q6ZVR7;
AC   Q8N7C6; Q8WW00; Q96NF4;
DE   RecName: Full=Adenylate kinase 9;
DE            Short=AK 9;
DE            EC=2.7.4.4;
DE            EC=2.7.4.6;
DE   AltName: Full=Adenylate kinase domain-containing protein 1;
DE   AltName: Full=Adenylate kinase domain-containing protein 2;
GN   Name=AK9; Synonyms=AKD1, AKD2, C6orf199, C6orf224;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0050145; F:nucleoside phosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0006757; P:ADP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006756; P:AMP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061508; P:CDP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061566; P:CMP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006174; P:dADP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061565; P:dAMP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061570; P:dCDP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061567; P:dCMP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006186; P:dGDP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061568; P:GDP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061571; P:TDP phosphorylation; IDA:UniProtKB.
DR   GO; GO:0061569; P:UDP phosphorylation; IDA:UniProtKB.
//
ID   KAIN_HUMAN              Reviewed;         427 AA.
AC   P29622; Q53XB5; Q86TR9; Q96BZ5;
DE   RecName: Full=Kallistatin;
DE   AltName: Full=Kallikrein inhibitor;
DE   AltName: Full=Peptidase inhibitor 4;
DE            Short=PI-4;
DE   AltName: Full=Serpin A4;
DE   Flags: Precursor;
GN   Name=SERPINA4; Synonyms=KST, PI4;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   KAL1L_HUMAN             Reviewed;         987 AA.
AC   A0AUZ9; B7ZLN1; I6L9A8; Q53TV8; Q53TW3; Q6IS05; Q8TCI1; Q96MI0;
AC   Q9UFC3;
DE   RecName: Full=KAT8 regulatory NSL complex subunit 1-like protein;
DE   AltName: Full=MSL1v2;
GN   Name=KANSL1L; Synonyms=C2orf67;
//
ID   KAISO_HUMAN             Reviewed;         672 AA.
AC   Q86T24; B2R5U6; O00319; Q7Z361; Q8IVP6; Q8N3P0;
DE   RecName: Full=Transcriptional regulator Kaiso;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 33;
GN   Name=ZBTB33; Synonyms=KAISO, ZNF348;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KALM_HUMAN              Reviewed;         680 AA.
AC   P23352; B2RPF8;
DE   RecName: Full=Anosmin-1;
DE   AltName: Full=Adhesion molecule-like X-linked;
DE   AltName: Full=Kallmann syndrome protein;
DE   Flags: Precursor;
GN   Name=KAL1; Synonyms=ADMLX, KAL, KALIG1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
//
ID   KALRN_HUMAN             Reviewed;        2985 AA.
AC   O60229; A8MSI4; C9JQ37; Q6ZN45; Q8TBQ5; Q9NSZ4; Q9Y2A5;
DE   RecName: Full=Kalirin;
DE            EC=2.7.11.1;
DE   AltName: Full=Huntingtin-associated protein-interacting protein;
DE   AltName: Full=Protein Duo;
DE   AltName: Full=Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain;
GN   Name=KALRN; Synonyms=DUET, DUO, HAPIP, TRAD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:HGNC.
DR   GO; GO:0007399; P:nervous system development; ISS:HGNC.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   KANK1_HUMAN             Reviewed;        1352 AA.
AC   Q14678; A2A2W8; D3DRH3; Q5W0W0; Q8IY65; Q8WX74;
DE   RecName: Full=KN motif and ankyrin repeat domain-containing protein 1;
DE   AltName: Full=Ankyrin repeat domain-containing protein 15;
DE   AltName: Full=Kidney ankyrin repeat-containing protein;
GN   Name=KANK1; Synonyms=ANKRD15, KANK, KIAA0172;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:2000393; P:negative regulation of lamellipodium morphogenesis; IDA:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:1900028; P:negative regulation of ruffle assembly; IDA:UniProtKB.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IMP:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0090303; P:positive regulation of wound healing; IMP:UniProtKB.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KANK2_HUMAN             Reviewed;         851 AA.
AC   Q63ZY3; B0I1P4; Q3KQZ3; Q6GUF5; Q9H8S4; Q9NUP0; Q9P210;
DE   RecName: Full=KN motif and ankyrin repeat domain-containing protein 2;
DE   AltName: Full=Ankyrin repeat domain-containing protein 25;
DE   AltName: Full=Matrix-remodeling-associated protein 3;
DE   AltName: Full=SRC-1-interacting protein;
DE            Short=SIP;
DE            Short=SRC-interacting protein;
DE            Short=SRC1-interacting protein;
GN   Name=KANK2; Synonyms=ANKRD25, KIAA1518, MXRA3, SIP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KANK3_HUMAN             Reviewed;         840 AA.
AC   Q6NY19; Q6NZI1; Q6ZQR3; Q8IUV2;
DE   RecName: Full=KN motif and ankyrin repeat domain-containing protein 3;
DE   AltName: Full=Ankyrin repeat domain-containing protein 47;
GN   Name=KANK3; Synonyms=ANKRD47;
//
ID   KANK4_HUMAN             Reviewed;         995 AA.
AC   Q5T7N3; B1ALP7; Q6P9A0; Q86T71; Q86VE6; Q8NAX3;
DE   RecName: Full=KN motif and ankyrin repeat domain-containing protein 4;
DE   AltName: Full=Ankyrin repeat domain-containing protein 38;
GN   Name=KANK4; Synonyms=ANKRD38;
//
ID   KANL1_HUMAN             Reviewed;        1105 AA.
AC   Q7Z3B3; A8K5E4; Q6AW85; Q8IYH1; Q9BRH0; Q9NTE7; Q9UFT0; Q9ULF3;
DE   RecName: Full=KAT8 regulatory NSL complex subunit 1;
DE   AltName: Full=MLL1/MLL complex subunit KANSL1;
DE   AltName: Full=MSL1 homolog 1;
DE            Short=hMSL1v1;
DE   AltName: Full=NSL complex protein NSL1;
DE   AltName: Full=Non-specific lethal 1 homolog;
GN   Name=KANSL1; Synonyms=KIAA1267, MSL1V1, NSL1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
//
ID   KANL3_HUMAN             Reviewed;         904 AA.
AC   Q9P2N6; A1L184; D3DXH3; D3DXH4; Q05BU4; Q6P3X2; Q6PJH6; Q86T19;
AC   Q96L64; Q9H0C9; Q9H8C9; Q9HAP8; Q9NWE5;
DE   RecName: Full=KAT8 regulatory NSL complex subunit 3;
DE   AltName: Full=NSL complex protein NSL3;
DE   AltName: Full=Non-specific lethal 3 homolog;
DE   AltName: Full=Serum inhibited-related protein;
DE   AltName: Full=Testis development protein PRTD;
GN   Name=KANSL3; Synonyms=KIAA1310, NSL3, PRTD, SI1;
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
//
ID   KANL2_HUMAN             Reviewed;         492 AA.
AC   Q9H9L4; Q8N3B5; Q96CV0; Q9NX51;
DE   RecName: Full=KAT8 regulatory NSL complex subunit 2;
DE   AltName: Full=NSL complex protein NSL2;
DE   AltName: Full=Non-specific lethal 2 homolog;
GN   Name=KANSL2; Synonyms=C12orf41, NSL2;
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
//
ID   KAP0_HUMAN              Reviewed;         381 AA.
AC   P10644; K7ER48; Q567S7;
DE   RecName: Full=cAMP-dependent protein kinase type I-alpha regulatory subunit;
DE   AltName: Full=Tissue-specific extinguisher 1;
DE            Short=TSE1;
DE   Contains:
DE     RecName: Full=cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed;
GN   Name=PRKAR1A; Synonyms=PKR1, PRKAR1, TSE1;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007143; P:female meiotic division; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:2000480; P:negative regulation of cAMP-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045835; P:negative regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KAP1_HUMAN              Reviewed;         381 AA.
AC   P31321; Q8N422;
DE   RecName: Full=cAMP-dependent protein kinase type I-beta regulatory subunit;
GN   Name=PRKAR1B;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; NAS:UniProtKB.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:2000480; P:negative regulation of cAMP-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KAP2_HUMAN              Reviewed;         404 AA.
AC   P13861; Q16823;
DE   RecName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit;
GN   Name=PRKAR2A; Synonyms=PKR2, PRKAR2;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:2000480; P:negative regulation of cAMP-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KAP3_HUMAN              Reviewed;         418 AA.
AC   P31323; A4D0R9;
DE   RecName: Full=cAMP-dependent protein kinase type II-beta regulatory subunit;
GN   Name=PRKAR2B;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004862; F:cAMP-dependent protein kinase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; IDA:BHF-UCL.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:2000480; P:negative regulation of cAMP-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KAPCA_HUMAN             Reviewed;         351 AA.
AC   P17612; Q32P54; Q9H2Y0; Q9NRB4; Q9NRH9;
DE   RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha;
DE            Short=PKA C-alpha;
DE            EC=2.7.11.11;
GN   Name=PRKACA; Synonyms=PKACA;
DR   GuidetoPHARMACOLOGY; 1476; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; TAS:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; TAS:BHF-UCL.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; TAS:BHF-UCL.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IDA:UniProtKB.
DR   GO; GO:0071374; P:cellular response to parathyroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; TAS:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:Reactome.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; TAS:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; TAS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; TAS:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
DR   GO; GO:0050804; P:regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048240; P:sperm capacitation; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KAPCB_HUMAN             Reviewed;         351 AA.
AC   P22694; B1APG4; B4DKB0; B4E2Q1; Q14VH1; Q59GC0; Q5BNE9; Q5BNF0;
AC   Q5BNF1; Q5BNF2; Q5BNF3; Q5CZ92; Q5T1K3; Q7Z3M1; Q8IYR5; Q8IZQ0;
AC   Q96B09;
DE   RecName: Full=cAMP-dependent protein kinase catalytic subunit beta;
DE            Short=PKA C-beta;
DE            EC=2.7.11.11;
GN   Name=PRKACB;
DR   GuidetoPHARMACOLOGY; 1477; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:Reactome.
DR   GO; GO:0051447; P:negative regulation of meiotic cell cycle; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0097338; P:response to clozapine; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KAPCG_HUMAN             Reviewed;         351 AA.
AC   P22612; O60850; Q5VZ02; Q86YI1;
DE   RecName: Full=cAMP-dependent protein kinase catalytic subunit gamma;
DE            Short=PKA C-gamma;
DE            EC=2.7.11.11;
GN   Name=PRKACG;
DR   GuidetoPHARMACOLOGY; 1478; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:Reactome.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   KASH5_HUMAN             Reviewed;         562 AA.
AC   Q8N6L0; Q96MC3;
DE   RecName: Full=Protein KASH5;
DE   AltName: Full=Coiled-coil domain-containing protein 155;
DE   AltName: Full=KASH domain-containing protein 5;
GN   Name=CCDC155; Synonyms=KASH5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   KAT1_HUMAN              Reviewed;         422 AA.
AC   Q16773; Q5T275; Q8N191;
DE   RecName: Full=Kynurenine--oxoglutarate transaminase 1;
DE            EC=2.6.1.7;
DE   AltName: Full=Cysteine-S-conjugate beta-lyase;
DE            EC=4.4.1.13;
DE   AltName: Full=Glutamine transaminase K;
DE            Short=GTK;
DE   AltName: Full=Glutamine--phenylpyruvate transaminase;
DE            EC=2.6.1.64;
DE   AltName: Full=Kynurenine aminotransferase I;
DE            Short=KATI;
DE   AltName: Full=Kynurenine--oxoglutarate transaminase I;
GN   Name=CCBL1;
DR   GO; GO:0047804; F:cysteine-S-conjugate beta-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047316; F:glutamine-phenylpyruvate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016212; F:kynurenine-oxoglutarate transaminase activity; IDA:UniProtKB.
DR   GO; GO:0047945; F:L-glutamine:pyruvate aminotransferase activity; EXP:Reactome.
DR   GO; GO:0036141; F:L-phenylalanine-oxaloacetate transaminase activity; TAS:Reactome.
DR   GO; GO:0047312; F:L-phenylalanine:pyruvate aminotransferase activity; EXP:Reactome.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; TAS:ProtInc.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006575; P:cellular modified amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0070189; P:kynurenine metabolic process; IDA:UniProtKB.
DR   GO; GO:0097053; P:L-kynurenine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
//
ID   KAT2A_HUMAN             Reviewed;         837 AA.
AC   Q92830; Q8N1A2; Q9UCW1;
DE   RecName: Full=Histone acetyltransferase KAT2A;
DE            EC=2.3.1.48;
DE   AltName: Full=General control of amino acid synthesis protein 5-like 2;
DE   AltName: Full=Histone acetyltransferase GCN5;
DE            Short=HsGCN5;
DE   AltName: Full=Lysine acetyltransferase 2A;
DE   AltName: Full=STAF97;
GN   Name=KAT2A; Synonyms=GCN5, GCN5L2, HGCN5;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0010484; F:H3 histone acetyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0043997; F:histone acetyltransferase activity (H4-K12 specific); IEA:Ensembl.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:ProtInc.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0044154; P:histone H3-K14 acetylation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0022037; P:metencephalon development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KAT2B_HUMAN             Reviewed;         832 AA.
AC   Q92831; Q6NSK1;
DE   RecName: Full=Histone acetyltransferase KAT2B;
DE            EC=2.3.1.48;
DE   AltName: Full=Histone acetyltransferase PCAF;
DE            Short=Histone acetylase PCAF;
DE   AltName: Full=Lysine acetyltransferase 2B;
DE   AltName: Full=P300/CBP-associated factor;
DE            Short=P/CAF;
GN   Name=KAT2B; Synonyms=PCAF;
DR   GuidetoPHARMACOLOGY; 2737; -.
DR   GO; GO:0016407; F:acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0004468; F:lysine N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0018393; P:internal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0018394; P:peptidyl-lysine acetylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006473; P:protein acetylation; TAS:ProtInc.
DR   GO; GO:0010835; P:regulation of protein ADP-ribosylation; IDA:BHF-UCL.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KAT3_HUMAN              Reviewed;         454 AA.
AC   Q6YP21; B3KQ13; O95335; Q5JS27; Q5T9T7; Q5T9T8; Q6AI27; Q6ICW1;
AC   Q9BVY5;
DE   RecName: Full=Kynurenine--oxoglutarate transaminase 3;
DE            EC=2.6.1.7;
DE   AltName: Full=Cysteine-S-conjugate beta-lyase 2;
DE            EC=4.4.1.13;
DE   AltName: Full=Kynurenine aminotransferase III;
DE            Short=KATIII;
DE   AltName: Full=Kynurenine--glyoxylate transaminase;
DE            EC=2.6.1.63;
DE   AltName: Full=Kynurenine--oxoglutarate transaminase III;
GN   Name=CCBL2; Synonyms=KAT3;
DR   GO; GO:0047804; F:cysteine-S-conjugate beta-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047315; F:kynurenine-glyoxylate transaminase activity; ISS:UniProtKB.
DR   GO; GO:0016212; F:kynurenine-oxoglutarate transaminase activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IEA:Ensembl.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0070189; P:kynurenine metabolic process; ISS:UniProtKB.
DR   GO; GO:0097052; P:L-kynurenine metabolic process; ISS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
//
ID   KAT5_HUMAN              Reviewed;         513 AA.
AC   Q92993; B4E3C7; C9JL99; O95624; Q13430; Q17RW5; Q561W3; Q6GSE8;
AC   Q9BWK7;
DE   RecName: Full=Histone acetyltransferase KAT5;
DE            EC=2.3.1.48;
DE   AltName: Full=60 kDa Tat-interactive protein;
DE            Short=Tip60;
DE   AltName: Full=Histone acetyltransferase HTATIP;
DE            Short=HIV-1 Tat interactive protein;
DE   AltName: Full=Lysine acetyltransferase 5;
DE   AltName: Full=cPLA(2)-interacting protein;
GN   Name=KAT5; Synonyms=HTATIP, TIP60;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IDA:UniProt.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0016573; P:histone acetylation; IDA:UniProtKB.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KAT6A_HUMAN             Reviewed;        2004 AA.
AC   Q92794; Q76L81;
DE   RecName: Full=Histone acetyltransferase KAT6A;
DE            EC=2.3.1.48;
DE   AltName: Full=MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3;
DE            Short=MYST-3;
DE   AltName: Full=Monocytic leukemia zinc finger protein;
DE   AltName: Full=Runt-related transcription factor-binding protein 2;
DE   AltName: Full=Zinc finger protein 220;
GN   Name=KAT6A; Synonyms=MOZ, MYST3, RUNXBP2, ZNF220;
DR   GO; GO:0016407; F:acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0090398; P:cellular senescence; IMP:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006323; P:DNA packaging; TAS:ProtInc.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0016573; P:histone acetylation; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006473; P:protein acetylation; IDA:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KAT6B_HUMAN             Reviewed;        2073 AA.
AC   Q8WYB5; O15087; Q86Y05; Q8WU81; Q9UKW2; Q9UKW3; Q9UKX0;
DE   RecName: Full=Histone acetyltransferase KAT6B;
DE            EC=2.3.1.48;
DE   AltName: Full=Histone acetyltransferase MOZ2;
DE   AltName: Full=MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;
DE            Short=MYST-4;
DE   AltName: Full=Monocytic leukemia zinc finger protein-related factor;
GN   Name=KAT6B; Synonyms=KIAA0383, MORF, MOZ2, MYST4;
DR   GO; GO:0016407; F:acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KAT7_HUMAN              Reviewed;         611 AA.
AC   O95251; B3KN74; B4DF85; B4DFB4; B4DFE0; B4DGY4; E7ER15; G5E9K7;
DE   RecName: Full=Histone acetyltransferase KAT7;
DE            EC=2.3.1.48;
DE   AltName: Full=Histone acetyltransferase binding to ORC1;
DE   AltName: Full=Lysine acetyltransferase 7;
DE   AltName: Full=MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2;
DE            Short=MYST-2;
GN   Name=KAT7; Synonyms=HBO1, HBOa, MYST2;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043983; P:histone H4-K12 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KAT8_HUMAN              Reviewed;         458 AA.
AC   Q9H7Z6; A8K4Z1; G5E9P2; Q659G0; Q7LC17; Q8IY59; Q8WYB4; Q8WZ14;
AC   Q9HAC5; Q9NR35;
DE   RecName: Full=Histone acetyltransferase KAT8;
DE            EC=2.3.1.48;
DE   AltName: Full=Lysine acetyltransferase 8;
DE   AltName: Full=MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1;
DE            Short=MYST-1;
DE            Short=hMOF;
GN   Name=KAT8; Synonyms=MOF, MYST1; ORFNames=PP7073;
DR   GO; GO:0016407; F:acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; IDA:UniProtKB.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KATL1_HUMAN             Reviewed;         490 AA.
AC   Q9BW62; A8K5X4;
DE   RecName: Full=Katanin p60 ATPase-containing subunit A-like 1;
DE            Short=Katanin p60 subunit A-like 1;
DE            EC=3.6.4.3;
DE   AltName: Full=p60 katanin-like 1;
GN   Name=KATNAL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008568; F:microtubule-severing ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051013; P:microtubule severing; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   KATL2_HUMAN             Reviewed;         538 AA.
AC   Q8IYT4;
DE   RecName: Full=Katanin p60 ATPase-containing subunit A-like 2;
DE            Short=Katanin p60 subunit A-like 2;
DE            EC=3.6.4.3;
DE   AltName: Full=p60 katanin-like 2;
GN   Name=KATNAL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008568; F:microtubule-severing ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051013; P:microtubule severing; IEA:UniProtKB-HAMAP.
//
ID   KAZD1_HUMAN             Reviewed;         304 AA.
AC   Q96I82; D3DR74; Q6ZMB1; Q9BQ73;
DE   RecName: Full=Kazal-type serine protease inhibitor domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=KAZALD1; ORFNames=FKSG28, FKSG40, UNQ2945/PRO21184;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
//
ID   KAZRN_HUMAN             Reviewed;         775 AA.
AC   Q674X7; B0QYQ0; B1AK78; Q5TGF1; Q674X4; Q674X6; Q6ZUD1; Q8IYN7;
AC   Q8N409; Q9UIL2; Q9UPX4;
DE   RecName: Full=Kazrin;
GN   Name=KAZN; Synonyms=KAZ, KIAA1026; ORFNames=HRIHFB2003;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   KBL_HUMAN               Reviewed;         419 AA.
AC   O75600; E2QC23; Q6ZWF1; Q96CA9;
DE   RecName: Full=2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial;
DE            Short=AKB ligase;
DE            EC=2.3.1.29;
DE   AltName: Full=Aminoacetone synthase;
DE   AltName: Full=Glycine acetyltransferase;
DE   Flags: Precursor;
GN   Name=GCAT; Synonyms=KBL;
DR   GO; GO:0008890; F:glycine C-acetyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; NAS:UniProtKB.
DR   GO; GO:0019518; P:L-threonine catabolic process to glycine; IEA:UniProtKB-UniPathway.
//
ID   KBP_HUMAN               Reviewed;         621 AA.
AC   Q96EK5; A8K5M8; Q9BR89; Q9ULE1; Q9Y428;
DE   RecName: Full=KIF1-binding protein;
GN   Name=KIAA1279; Synonyms=KBP;
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006839; P:mitochondrial transport; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   KBRS1_HUMAN             Reviewed;         192 AA.
AC   Q9NYS0; Q96K18;
DE   RecName: Full=NF-kappa-B inhibitor-interacting Ras-like protein 1;
DE   AltName: Full=I-kappa-B-interacting Ras-like protein 1;
DE            Short=Kappa B-Ras protein 1;
DE            Short=KappaB-Ras1;
GN   Name=NKIRAS1; Synonyms=KBRAS1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   KBRS2_HUMAN             Reviewed;         191 AA.
AC   Q9NYR9; A6NCZ5; B3KNN0; B4DNM3; Q6PK52; Q96KC7; Q9NSX1;
DE   RecName: Full=NF-kappa-B inhibitor-interacting Ras-like protein 2;
DE   AltName: Full=I-kappa-B-interacting Ras-like protein 2;
DE            Short=Kappa B-Ras protein 2;
DE            Short=KappaB-Ras2;
GN   Name=NKIRAS2; Synonyms=KBRAS2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   KBTB2_HUMAN             Reviewed;         623 AA.
AC   Q8IY47; A8K9T7; Q86Y62; Q9P239; Q9UFM7; Q9Y382;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 2;
DE   AltName: Full=BTB and kelch domain-containing protein 1;
GN   Name=KBTBD2; Synonyms=BKLHD1, KIAA1489; ORFNames=CGI-73;
//
ID   KBTB3_HUMAN             Reviewed;         608 AA.
AC   Q8NAB2; Q6N066; Q86X38; Q96NK5;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 3;
DE   AltName: Full=BTB and kelch domain-containing protein 3;
GN   Name=KBTBD3; Synonyms=BKLHD3;
//
ID   KBTB4_HUMAN             Reviewed;         518 AA.
AC   Q9NVX7; D3DQS1; D3DQS2; Q6IA85; Q9BUC3; Q9NV76;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 4;
DE   AltName: Full=BTB and kelch domain-containing protein 4;
GN   Name=KBTBD4; Synonyms=BKLHD4;
//
ID   KBTB6_HUMAN             Reviewed;         674 AA.
AC   Q86V97; Q5T6Y8; Q8N8L0; Q8NDM5; Q96MP6;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 6;
GN   Name=KBTBD6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   KBTB8_HUMAN             Reviewed;         601 AA.
AC   Q8NFY9; Q96JI5;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 8;
DE   AltName: Full=T-cell activation kelch repeat protein;
DE            Short=TA-KRP;
GN   Name=KBTBD8; Synonyms=KIAA1842, TAKRP;
//
ID   KBTB7_HUMAN             Reviewed;         684 AA.
AC   Q8WVZ9; B5TZ86; Q5T6Y7; Q8NB99; Q9H0I6;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 7;
GN   Name=KBTBD7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   KBTBD_HUMAN             Reviewed;         458 AA.
AC   C9JR72;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 13;
GN   Name=KBTBD13;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   KBTBB_HUMAN             Reviewed;         623 AA.
AC   O94819; Q3L1I0;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 11;
DE   AltName: Full=Chronic myelogenous leukemia-associated protein;
DE   AltName: Full=Kelch domain-containing protein 7B;
GN   Name=KBTBD11; Synonyms=CMLAP, KIAA0711, KLHDC7C;
//
ID   KBTBC_HUMAN             Reviewed;         623 AA.
AC   Q3ZCT8; B5MCC6; Q6ZRK1;
DE   RecName: Full=Kelch repeat and BTB domain-containing protein 12;
DE   AltName: Full=Kelch domain-containing protein 6;
GN   Name=KBTBD12; Synonyms=KLHDC6;
//
ID   KC1AL_HUMAN             Reviewed;         337 AA.
AC   Q8N752; Q5T2N2;
DE   RecName: Full=Casein kinase I isoform alpha-like;
DE            Short=CKI-alpha-like;
DE            EC=2.7.11.1;
DE   AltName: Full=CK1;
GN   Name=CSNK1A1L;
DR   GuidetoPHARMACOLOGY; 1996; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KC1A_HUMAN              Reviewed;         337 AA.
AC   P48729; D3DQG0; D3DQG1; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q96HD2;
AC   Q9UDK3;
DE   RecName: Full=Casein kinase I isoform alpha;
DE            Short=CKI-alpha;
DE            EC=2.7.11.1;
DE   AltName: Full=CK1;
GN   Name=CSNK1A1;
DR   GuidetoPHARMACOLOGY; 1995; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KC1D_HUMAN              Reviewed;         415 AA.
AC   P48730; A2I2P2; Q96KZ6; Q9BTN5;
DE   RecName: Full=Casein kinase I isoform delta;
DE            Short=CKI-delta;
DE            Short=CKId;
DE            EC=2.7.11.1;
DE   AltName: Full=Tau-protein kinase CSNK1D;
DE            EC=2.7.11.26;
GN   Name=CSNK1D; Synonyms=HCKID;
DR   GuidetoPHARMACOLOGY; 1997; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0050321; F:tau-protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051225; P:spindle assembly; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KC1E_HUMAN              Reviewed;         416 AA.
AC   P49674;
DE   RecName: Full=Casein kinase I isoform epsilon;
DE            Short=CKI-epsilon;
DE            Short=CKIe;
DE            EC=2.7.11.1;
GN   Name=CSNK1E;
DR   GuidetoPHARMACOLOGY; 1998; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KC1G1_HUMAN             Reviewed;         422 AA.
AC   Q9HCP0; Q5JPH1; Q96AE9; Q9HCP1;
DE   RecName: Full=Casein kinase I isoform gamma-1;
DE            Short=CKI-gamma 1;
DE            EC=2.7.11.1;
GN   Name=CSNK1G1;
DR   GuidetoPHARMACOLOGY; 1999; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KC1G2_HUMAN             Reviewed;         415 AA.
AC   P78368; B5BU42; O00704; Q8WUB1;
DE   RecName: Full=Casein kinase I isoform gamma-2;
DE            Short=CKI-gamma 2;
DE            EC=2.7.11.1;
GN   Name=CSNK1G2; Synonyms=CK1G2;
DR   GuidetoPHARMACOLOGY; 2000; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KC1G3_HUMAN             Reviewed;         447 AA.
AC   Q9Y6M4; A8K040; B4DSH2; B7Z9Q4; E7EVD0; Q86WZ7; Q9Y6M3;
DE   RecName: Full=Casein kinase I isoform gamma-3;
DE            Short=CKI-gamma 3;
DE            EC=2.7.11.1;
GN   Name=CSNK1G3;
DR   GuidetoPHARMACOLOGY; 2001; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KCA10_HUMAN             Reviewed;         511 AA.
AC   Q16322;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 10;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.8;
GN   Name=KCNA10;
DR   GuidetoPHARMACOLOGY; 545; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005221; F:intracellular cyclic nucleotide activated cation channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCAB1_HUMAN             Reviewed;         419 AA.
AC   Q14722; A8K9H8; A8KAD4; B3KPZ4; Q13031; Q13302; Q16547; Q6PI60;
AC   Q99869;
DE   RecName: Full=Voltage-gated potassium channel subunit beta-1;
DE   AltName: Full=K(+) channel subunit beta-1;
DE   AltName: Full=Kv-beta-1;
GN   Name=KCNAB1; Synonyms=KCNA1B;
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCAB2_HUMAN             Reviewed;         367 AA.
AC   Q13303; A0AVM9; A8K1A4; B0AZR7; O43659; Q5TG82; Q5TG83; Q6ZNE4;
AC   Q99411;
DE   RecName: Full=Voltage-gated potassium channel subunit beta-2;
DE   AltName: Full=K(+) channel subunit beta-2;
DE   AltName: Full=Kv-beta-2;
DE            Short=hKvbeta2;
GN   Name=KCNAB2; Synonyms=KCNA2B, KCNK2;
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCAB3_HUMAN             Reviewed;         404 AA.
AC   O43448; Q4VAW0;
DE   RecName: Full=Voltage-gated potassium channel subunit beta-3;
DE   AltName: Full=K(+) channel subunit beta-3;
DE   AltName: Full=Kv-beta-3;
GN   Name=KCNAB3; Synonyms=KCNA3B;
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCC1A_HUMAN             Reviewed;         370 AA.
AC   Q14012; Q3KPF6;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type 1;
DE            EC=2.7.11.17;
DE   AltName: Full=CaM kinase I;
DE            Short=CaM-KI;
DE   AltName: Full=CaM kinase I alpha;
DE            Short=CaMKI-alpha;
GN   Name=CAMK1;
DR   GuidetoPHARMACOLOGY; 1952; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; IMP:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0051835; P:positive regulation of synapse structural plasticity; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051147; P:regulation of muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KCC1B_HUMAN             Reviewed;         343 AA.
AC   Q6P2M8; B4DJR8; B4E1A6; B7WPG0; D3DWU7; Q8N4R0;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type 1B;
DE            EC=2.7.11.17;
DE   AltName: Full=CaM kinase I beta;
DE            Short=CaM kinase IB;
DE            Short=CaM-KI beta;
DE            Short=CaMKI-beta;
DE   AltName: Full=Pregnancy up-regulated non-ubiquitously-expressed CaM kinase;
GN   Name=PNCK;
DR   GuidetoPHARMACOLOGY; 2172; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
//
ID   KCC1D_HUMAN             Reviewed;         385 AA.
AC   Q8IU85; B0YIY0; Q9HD31;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type 1D;
DE            EC=2.7.11.17;
DE   AltName: Full=CaM kinase I delta;
DE            Short=CaM kinase ID;
DE            Short=CaM-KI delta;
DE            Short=CaMKI delta;
DE            Short=CaMKID;
DE   AltName: Full=CaMKI-like protein kinase;
DE            Short=CKLiK;
GN   Name=CAMK1D; Synonyms=CAMKID;
DR   GuidetoPHARMACOLOGY; 1953; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IMP:UniProtKB.
DR   GO; GO:0060267; P:positive regulation of respiratory burst; IMP:UniProtKB.
DR   GO; GO:0050773; P:regulation of dendrite development; IMP:UniProtKB.
DR   GO; GO:0071622; P:regulation of granulocyte chemotaxis; IMP:UniProtKB.
//
ID   KCC1G_HUMAN             Reviewed;         476 AA.
AC   Q96NX5; Q86UH5; Q9Y3J7;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type 1G;
DE            EC=2.7.11.17;
DE   AltName: Full=CaM kinase I gamma;
DE            Short=CaM kinase IG;
DE            Short=CaM-KI gamma;
DE            Short=CaMKI gamma;
DE            Short=CaMKIG;
DE   AltName: Full=CaMK-like CREB kinase III;
DE            Short=CLICK III;
GN   Name=CAMK1G; Synonyms=CLICK3, VWS1;
DR   GuidetoPHARMACOLOGY; 1954; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
//
ID   KCC2A_HUMAN             Reviewed;         478 AA.
AC   Q9UQM7; Q9UL21; Q9Y2H4; Q9Y352;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type II subunit alpha;
DE            Short=CaM kinase II subunit alpha;
DE            Short=CaMK-II subunit alpha;
DE            EC=2.7.11.17;
GN   Name=CAMK2A; Synonyms=CAMKA, KIAA0968;
DR   GuidetoPHARMACOLOGY; 1555; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016301; F:kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCC2B_HUMAN             Reviewed;         666 AA.
AC   Q13554; A4D2K0; A4D2K1; A4D2K2; A4D2K3; A4D2K4; A4D2K5; A4D2K6;
AC   O95437; O95438; O95599; Q9UGH7; Q9UGH8; Q9UGH9; Q9UNX0; Q9UNX7;
AC   Q9UP00; Q9Y5N4; Q9Y6F4;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type II subunit beta;
DE            Short=CaM kinase II subunit beta;
DE            Short=CaMK-II subunit beta;
DE            EC=2.7.11.17;
GN   Name=CAMK2B; Synonyms=CAM2, CAMK2, CAMKB;
DR   GuidetoPHARMACOLOGY; 1556; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0060466; P:activation of meiosis involved in egg activation; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0002030; P:inhibitory G-protein coupled receptor phosphorylation; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.
DR   GO; GO:0060998; P:regulation of dendritic spine development; TAS:UniProtKB.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.
DR   GO; GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.
DR   GO; GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
DR   GO; GO:0032222; P:regulation of synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCC2D_HUMAN             Reviewed;         499 AA.
AC   Q13557; A8MVS8; Q52PK4; Q59G21; Q8N553; Q9UGH6; Q9UQE9;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type II subunit delta;
DE            Short=CaM kinase II subunit delta;
DE            Short=CaMK-II subunit delta;
DE            EC=2.7.11.17;
GN   Name=CAMK2D; Synonyms=CAMKD;
DR   GuidetoPHARMACOLOGY; 1558; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0086003; P:cardiac muscle cell contraction; ISS:BHF-UCL.
DR   GO; GO:0071277; P:cellular response to calcium ion; TAS:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0060341; P:regulation of cellular localization; IMP:UniProtKB.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:UniProtKB.
DR   GO; GO:1901725; P:regulation of histone deacetylase activity; TAS:BHF-UCL.
DR   GO; GO:1901897; P:regulation of relaxation of cardiac muscle; IDA:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; TAS:UniProtKB.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; TAS:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; ISS:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCC2G_HUMAN             Reviewed;         558 AA.
AC   Q13555; O00561; O15378; Q13279; Q13282; Q13556; Q5SQZ3; Q5SQZ4;
AC   Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type II subunit gamma;
DE            Short=CaM kinase II subunit gamma;
DE            Short=CaMK-II subunit gamma;
DE            EC=2.7.11.17;
GN   Name=CAMK2G; Synonyms=CAMK, CAMK-II, CAMKG;
DR   GuidetoPHARMACOLOGY; 1557; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; NAS:UniProtKB.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; NAS:GOC.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; NAS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.
DR   GO; GO:1901897; P:regulation of relaxation of cardiac muscle; IEA:Ensembl.
DR   GO; GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCC4_HUMAN              Reviewed;         473 AA.
AC   Q16566; D3DSZ7;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase type IV;
DE            Short=CaMK IV;
DE            EC=2.7.11.17;
DE   AltName: Full=CaM kinase-GR;
GN   Name=CAMK4; Synonyms=CAMK, CAMK-GR, CAMKIV;
DR   GuidetoPHARMACOLOGY; 1955; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007616; P:long-term memory; IGI:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IMP:UniProtKB.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; TAS:UniProtKB.
DR   GO; GO:0033081; P:regulation of T cell differentiation in thymus; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCD12_HUMAN             Reviewed;         325 AA.
AC   Q96CX2;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD12;
DE   AltName: Full=Pfetin;
DE   AltName: Full=Predominantly fetal expressed T1 domain;
GN   Name=KCTD12; Synonyms=C13orf2, KIAA1778, PFET1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD15_HUMAN             Reviewed;         283 AA.
AC   Q96SI1; A8K600; Q9BVI6;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD15;
DE   AltName: Full=Potassium channel tetramerization domain-containing protein 15;
GN   Name=KCTD15;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD11_HUMAN             Reviewed;         232 AA.
AC   Q693B1; B3KPE0;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD11;
GN   Name=KCTD11; Synonyms=C17orf36, REN;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   KCD14_HUMAN             Reviewed;         255 AA.
AC   Q9BQ13; B2R9R8;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD14;
GN   Name=KCTD14;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD16_HUMAN             Reviewed;         428 AA.
AC   Q68DU8; Q9P2M9;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD16;
DE   AltName: Full=Potassium channel tetramerization domain-containing protein 16;
GN   Name=KCTD16; Synonyms=KIAA1317;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
//
ID   KCD17_HUMAN             Reviewed;         321 AA.
AC   Q8N5Z5; B0QYA9; B0QYB0; O95517;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD17;
GN   Name=KCTD17;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD19_HUMAN             Reviewed;         926 AA.
AC   Q17RG1; B4DZ49; Q8N804;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD19;
GN   Name=KCTD19;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD18_HUMAN             Reviewed;         426 AA.
AC   Q6PI47; Q53T21; Q6NW26; Q6PCD8; Q8N9B7; Q96N73;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD18;
GN   Name=KCTD18;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD20_HUMAN             Reviewed;         419 AA.
AC   Q7Z5Y7; B4E2Q3; Q5W105; Q69YQ7; Q8IZ55;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD20;
GN   Name=KCTD20; Synonyms=C6orf69;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCD21_HUMAN             Reviewed;         260 AA.
AC   Q4G0X4; B4DTR0;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD21;
GN   Name=KCTD21;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCE1L_HUMAN             Reviewed;         142 AA.
AC   Q9UJ90;
DE   RecName: Full=Potassium voltage-gated channel subfamily E member 1-like protein;
DE   AltName: Full=AMME syndrome candidate gene 2 protein;
GN   Name=KCNE1L; Synonyms=AMMECR2;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0086013; P:membrane repolarization during cardiac muscle cell action potential; IMP:GOC.
DR   GO; GO:1901380; P:negative regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060372; P:regulation of atrial cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:2001257; P:regulation of cation channel activity; IDA:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:1901379; P:regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   KCIP1_HUMAN             Reviewed;         227 AA.
AC   Q9NZI2; B7Z7B4; Q3YAD0; Q3YAD1; Q3YAD2; Q3YAD3; Q5U822;
DE   RecName: Full=Kv channel-interacting protein 1;
DE            Short=KChIP1;
DE   AltName: Full=A-type potassium channel modulatory protein 1;
DE   AltName: Full=Potassium channel-interacting protein 1;
DE   AltName: Full=Vesicle APC-binding protein;
GN   Name=KCNIP1; Synonyms=KCHIP1, VABP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005513; P:detection of calcium ion; TAS:ProtInc.
DR   GO; GO:0045760; P:positive regulation of action potential; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   KCIP2_HUMAN             Reviewed;         270 AA.
AC   Q9NS61; A6NJE5; A8MQ75; Q3YAC6; Q3YAC8; Q3YAC9; Q7Z6F1; Q96K86;
AC   Q96T41; Q96T42; Q96T43; Q96T44; Q9H0N4; Q9HD10; Q9HD11; Q9NS60;
AC   Q9NY10; Q9NZI1;
DE   RecName: Full=Kv channel-interacting protein 2;
DE            Short=KChIP2;
DE   AltName: Full=A-type potassium channel modulatory protein 2;
DE   AltName: Full=Cardiac voltage-gated potassium channel modulatory subunit;
DE   AltName: Full=Potassium channel-interacting protein 2;
GN   Name=KCNIP2; Synonyms=KCHIP2;
DR   GO; GO:0005250; F:A-type (transient outward) potassium channel activity; TAS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0046923; F:ER retention sequence binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0045163; P:clustering of voltage-gated potassium channels; IDA:UniProtKB.
DR   GO; GO:0005513; P:detection of calcium ion; TAS:ProtInc.
DR   GO; GO:0086009; P:membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; NAS:UniProtKB.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006813; P:potassium ion transport; TAS:UniProtKB.
DR   GO; GO:2001257; P:regulation of cation channel activity; TAS:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
//
ID   KCIP4_HUMAN             Reviewed;         250 AA.
AC   Q6PIL6; Q3YAB8; Q3YAB9; Q3YAC0; Q3YAC1; Q3YAC2; Q4W5G8; Q8NEU0;
AC   Q9BWT2; Q9H294; Q9H2A4;
DE   RecName: Full=Kv channel-interacting protein 4;
DE            Short=KChIP4;
DE   AltName: Full=A-type potassium channel modulatory protein 4;
DE   AltName: Full=Calsenilin-like protein;
DE   AltName: Full=Potassium channel-interacting protein 4;
GN   Name=KCNIP4; Synonyms=CALP, KCHIP4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
//
ID   KCJ10_HUMAN             Reviewed;         379 AA.
AC   P78508; A3KME7; Q5VUT9; Q8N4I7; Q92808;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 10;
DE   AltName: Full=ATP-dependent inwardly rectifying potassium channel Kir4.1;
DE   AltName: Full=Inward rectifier K(+) channel Kir1.2;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 10;
GN   Name=KCNJ10;
DR   GuidetoPHARMACOLOGY; 438; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0051935; P:L-glutamate uptake involved in synaptic transmission; IEA:Ensembl.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0021554; P:optic nerve development; IEA:Ensembl.
DR   GO; GO:0055075; P:potassium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0010107; P:potassium ion import; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0060075; P:regulation of resting membrane potential; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0009637; P:response to blue light; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0051385; P:response to mineralocorticoid; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   KCJ11_HUMAN             Reviewed;         390 AA.
AC   Q14654; B4DWI4; E9PNK0; Q2M1H7; Q58EX3; Q8IW96;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 11;
DE   AltName: Full=IKATP;
DE   AltName: Full=Inward rectifier K(+) channel Kir6.2;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 11;
GN   Name=KCNJ11;
DR   GuidetoPHARMACOLOGY; 442; -.
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; ISS:BHF-UCL.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0030955; F:potassium ion binding; TAS:BHF-UCL.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071316; P:cellular response to nicotine; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0050877; P:neurological system process; IMP:BHF-UCL.
DR   GO; GO:2001259; P:positive regulation of cation channel activity; IEA:Ensembl.
DR   GO; GO:0010107; P:potassium ion import; ISS:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0033198; P:response to ATP; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IMP:BHF-UCL.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCJ12_HUMAN             Reviewed;         433 AA.
AC   Q14500; O43401; Q15756; Q8NG63;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 12;
DE   AltName: Full=Inward rectifier K(+) channel Kir2.2;
DE            Short=IRK-2;
DE   AltName: Full=Inward rectifier K(+) channel Kir2.2v;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 12;
GN   Name=KCNJ12; Synonyms=IRK2, KCNJN1;
DR   GuidetoPHARMACOLOGY; 431; -.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCJ13_HUMAN             Reviewed;         360 AA.
AC   O60928; A0PGH1; O76023; Q53SA1; Q8N3Y4;
DE   RecName: Full=Inward rectifier potassium channel 13;
DE   AltName: Full=Inward rectifier K(+) channel Kir7.1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 13;
GN   Name=KCNJ13;
DR   GuidetoPHARMACOLOGY; 443; -.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; NAS:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
//
ID   KCJ14_HUMAN             Reviewed;         436 AA.
AC   Q9UNX9;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 14;
DE   AltName: Full=Inward rectifier K(+) channel Kir2.4;
DE            Short=IRK-4;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 14;
GN   Name=KCNJ14; Synonyms=IRK4;
DR   GuidetoPHARMACOLOGY; 433; -.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCJ15_HUMAN             Reviewed;         375 AA.
AC   Q99712; D3DSH5; O00564; Q96L28; Q99446;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 15;
DE   AltName: Full=Inward rectifier K(+) channel Kir1.3;
DE   AltName: Full=Inward rectifier K(+) channel Kir4.2;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 15;
GN   Name=KCNJ15; Synonyms=KCNJ14;
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCJ16_HUMAN             Reviewed;         418 AA.
AC   Q9NPI9;
DE   RecName: Full=Inward rectifier potassium channel 16;
DE   AltName: Full=Inward rectifier K(+) channel Kir5.1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 16;
GN   Name=KCNJ16;
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; NAS:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCJ18_HUMAN             Reviewed;         433 AA.
AC   B7U540;
DE   RecName: Full=Inward rectifier potassium channel 18;
DE   AltName: Full=Inward rectifier K(+) channel Kir2.6;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 18;
GN   Name=KCNJ18;
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
//
ID   KCMA1_HUMAN             Reviewed;        1236 AA.
AC   Q12791; F8WA96; Q12886; Q12917; Q12921; Q12960; Q13150; Q5JQ23;
AC   Q5SQR9; Q96LG8; Q9UBB0; Q9UCX0; Q9UQK6;
DE   RecName: Full=Calcium-activated potassium channel subunit alpha-1;
DE   AltName: Full=BK channel;
DE   AltName: Full=BKCA alpha;
DE   AltName: Full=Calcium-activated potassium channel, subfamily M subunit alpha-1;
DE   AltName: Full=K(VCA)alpha;
DE   AltName: Full=KCa1.1;
DE   AltName: Full=Maxi K channel;
DE            Short=MaxiK;
DE   AltName: Full=Slo-alpha;
DE   AltName: Full=Slo1;
DE   AltName: Full=Slowpoke homolog;
DE            Short=Slo homolog;
DE            Short=hSlo;
GN   Name=KCNMA1; Synonyms=KCNMA, SLO;
DR   GuidetoPHARMACOLOGY; 380; -.
DR   GO; GO:0003779; F:actin binding; IDA:BHF-UCL.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0060072; F:large conductance calcium-activated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0030007; P:cellular potassium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0060082; P:eye blink reflex; IEA:Ensembl.
DR   GO; GO:0045475; P:locomotor rhythm; IEA:Ensembl.
DR   GO; GO:0060073; P:micturition; IDA:UniProtKB.
DR   GO; GO:0045794; P:negative regulation of cell volume; IDA:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0032344; P:regulation of aldosterone metabolic process; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:UniProtKB.
DR   GO; GO:0060087; P:relaxation of vascular smooth muscle; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0034465; P:response to carbon monoxide; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0006970; P:response to osmotic stress; IDA:UniProtKB.
DR   GO; GO:0046541; P:saliva secretion; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0060083; P:smooth muscle contraction involved in micturition; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCMB1_HUMAN             Reviewed;         191 AA.
AC   Q16558; O00707; O00708; P78475; Q53YR0; Q8TAX3; Q93005;
DE   RecName: Full=Calcium-activated potassium channel subunit beta-1;
DE   AltName: Full=BK channel subunit beta-1;
DE            Short=BKbeta;
DE            Short=BKbeta1;
DE            Short=Hbeta1;
DE   AltName: Full=Calcium-activated potassium channel, subfamily M subunit beta-1;
DE            Short=Calcium-activated potassium channel subunit beta;
DE   AltName: Full=Charybdotoxin receptor subunit beta-1;
DE   AltName: Full=K(VCA)beta-1;
DE   AltName: Full=Maxi K channel subunit beta-1;
DE   AltName: Full=Slo-beta-1;
DE            Short=Slo-beta;
GN   Name=KCNMB1;
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCMB3_HUMAN             Reviewed;         279 AA.
AC   Q9NPA1; B7Z9C9; D3DNR2; E9PER5; Q9NPG7; Q9NRM9; Q9UHN3;
DE   RecName: Full=Calcium-activated potassium channel subunit beta-3;
DE   AltName: Full=BK channel subunit beta-3;
DE            Short=BKbeta3;
DE            Short=Hbeta3;
DE   AltName: Full=Calcium-activated potassium channel, subfamily M subunit beta-3;
DE   AltName: Full=Charybdotoxin receptor subunit beta-3;
DE   AltName: Full=K(VCA)beta-3;
DE   AltName: Full=Maxi K channel subunit beta-3;
DE   AltName: Full=Slo-beta-3;
GN   Name=KCNMB3; Synonyms=KCNMB2, KCNMBL;
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; NAS:UniProtKB.
DR   GO; GO:0001508; P:action potential; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005513; P:detection of calcium ion; IDA:UniProtKB.
DR   GO; GO:0019228; P:neuronal action potential; IDA:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCMB2_HUMAN             Reviewed;         235 AA.
AC   Q9Y691;
DE   RecName: Full=Calcium-activated potassium channel subunit beta-2;
DE   AltName: Full=BK channel subunit beta-2;
DE            Short=BKbeta2;
DE            Short=Hbeta2;
DE   AltName: Full=Calcium-activated potassium channel, subfamily M subunit beta-2;
DE   AltName: Full=Charybdotoxin receptor subunit beta-2;
DE   AltName: Full=Hbeta3;
DE   AltName: Full=K(VCA)beta-2;
DE   AltName: Full=Maxi K channel subunit beta-2;
DE   AltName: Full=Slo-beta-2;
GN   Name=KCNMB2;
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0008200; F:ion channel inhibitor activity; TAS:ProtInc.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0001508; P:action potential; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005513; P:detection of calcium ion; IDA:UniProtKB.
DR   GO; GO:0019228; P:neuronal action potential; IDA:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0019229; P:regulation of vasoconstriction; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCMB4_HUMAN             Reviewed;         210 AA.
AC   Q86W47; Q8IVR3; Q9NPA4; Q9P0G5;
DE   RecName: Full=Calcium-activated potassium channel subunit beta-4;
DE   AltName: Full=BK channel subunit beta-4;
DE            Short=BKbeta4;
DE            Short=Hbeta4;
DE   AltName: Full=Calcium-activated potassium channel, subfamily M subunit beta-4;
DE   AltName: Full=Charybdotoxin receptor subunit beta-4;
DE   AltName: Full=K(VCA)beta-4;
DE   AltName: Full=Maxi K channel subunit beta-4;
DE   AltName: Full=Slo-beta-4;
GN   Name=KCNMB4;
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001508; P:action potential; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005513; P:detection of calcium ion; IDA:UniProtKB.
DR   GO; GO:0019228; P:neuronal action potential; IDA:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; TAS:UniProtKB.
DR   GO; GO:0019229; P:regulation of vasoconstriction; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCMF1_HUMAN             Reviewed;         381 AA.
AC   Q9P0J7; Q4ZG04; Q53SC7; Q9BWK2; Q9H8P5; Q9UFE8;
DE   RecName: Full=E3 ubiquitin-protein ligase KCMF1;
DE            EC=6.3.2.-;
DE   AltName: Full=FGF-induced in gastric cancer;
DE   AltName: Full=Potassium channel modulatory factor;
DE            Short=PCMF;
DE   AltName: Full=ZZ-type zinc finger-containing protein 1;
GN   Name=KCMF1; Synonyms=FIGC, ZZZ1;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   KCNA1_HUMAN             Reviewed;         495 AA.
AC   Q09470; A6NM83; Q3MIQ9;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 1;
DE   AltName: Full=Voltage-gated K(+) channel HuKI;
DE   AltName: Full=Voltage-gated potassium channel HBK1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.1;
GN   Name=KCNA1;
DR   GuidetoPHARMACOLOGY; 538; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNA2_HUMAN             Reviewed;         499 AA.
AC   P16389; Q86XG6;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 2;
DE   AltName: Full=NGK1;
DE   AltName: Full=Voltage-gated K(+) channel HuKIV;
DE   AltName: Full=Voltage-gated potassium channel HBK5;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.2;
GN   Name=KCNA2;
DR   GuidetoPHARMACOLOGY; 539; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0021633; P:optic nerve structural organization; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNA3_HUMAN             Reviewed;         575 AA.
AC   P22001; Q5VWN2;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 3;
DE   AltName: Full=HGK5;
DE   AltName: Full=HLK3;
DE   AltName: Full=HPCN3;
DE   AltName: Full=Voltage-gated K(+) channel HuKIII;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.3;
GN   Name=KCNA3; Synonyms=HGK5;
DR   GuidetoPHARMACOLOGY; 540; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNA4_HUMAN             Reviewed;         653 AA.
AC   P22459;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 4;
DE   AltName: Full=HPCN2;
DE   AltName: Full=Voltage-gated K(+) channel HuKII;
DE   AltName: Full=Voltage-gated potassium channel HBK4;
DE   AltName: Full=Voltage-gated potassium channel HK1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.4;
GN   Name=KCNA4; Synonyms=KCNA4L;
DR   GuidetoPHARMACOLOGY; 541; -.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNA5_HUMAN             Reviewed;         613 AA.
AC   P22460; Q4KKT8; Q4VAJ1; Q4VAJ2; Q9UDA4;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 5;
DE   AltName: Full=HPCN1;
DE   AltName: Full=Voltage-gated potassium channel HK2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.5;
GN   Name=KCNA5;
DR   GuidetoPHARMACOLOGY; 542; -.
DR   GO; GO:0051393; F:alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0019870; F:potassium channel inhibitor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0086089; F:voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0060081; P:membrane hyperpolarization; IMP:BHF-UCL.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:2000288; P:positive regulation of myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0055075; P:potassium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; IDA:MGI.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0060372; P:regulation of atrial cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0043266; P:regulation of potassium ion transport; IMP:BHF-UCL.
DR   GO; GO:0019229; P:regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNA6_HUMAN             Reviewed;         529 AA.
AC   P17658;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 6;
DE   AltName: Full=Voltage-gated potassium channel HBK2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.6;
GN   Name=KCNA6;
DR   GuidetoPHARMACOLOGY; 543; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNA7_HUMAN             Reviewed;         456 AA.
AC   Q96RP8; A1KYX7; Q9BYS4;
DE   RecName: Full=Potassium voltage-gated channel subfamily A member 7;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv1.7;
GN   Name=KCNA7;
DR   GuidetoPHARMACOLOGY; 544; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNB1_HUMAN             Reviewed;         858 AA.
AC   Q14721; Q14193;
DE   RecName: Full=Potassium voltage-gated channel subfamily B member 1;
DE   AltName: Full=Delayed rectifier potassium channel 1;
DE            Short=DRK1;
DE            Short=h-DRK1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv2.1;
GN   Name=KCNB1;
DR   GuidetoPHARMACOLOGY; 546; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNB2_HUMAN             Reviewed;         911 AA.
AC   Q92953; Q7Z7D0; Q9BXD3;
DE   RecName: Full=Potassium voltage-gated channel subfamily B member 2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv2.2;
GN   Name=KCNB2;
DR   GuidetoPHARMACOLOGY; 547; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNC1_HUMAN             Reviewed;         511 AA.
AC   P48547;
DE   RecName: Full=Potassium voltage-gated channel subfamily C member 1;
DE   AltName: Full=NGK2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv3.1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv4;
GN   Name=KCNC1;
DR   GuidetoPHARMACOLOGY; 548; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNC2_HUMAN             Reviewed;         638 AA.
AC   Q96PR1; B7Z231; F5H030; J3KPP5; Q4LE77; Q86W09; Q8N1V9; Q96PR0;
DE   RecName: Full=Potassium voltage-gated channel subfamily C member 2;
DE   AltName: Full=Voltage-gated potassium channel Kv3.2;
GN   Name=KCNC2;
DR   GuidetoPHARMACOLOGY; 549; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0001508; P:action potential; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNC3_HUMAN             Reviewed;         757 AA.
AC   Q14003;
DE   RecName: Full=Potassium voltage-gated channel subfamily C member 3;
DE   AltName: Full=KSHIIID;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv3.3;
GN   Name=KCNC3;
DR   GuidetoPHARMACOLOGY; 550; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNC4_HUMAN             Reviewed;         635 AA.
AC   Q03721; Q3MIM4; Q5TBI6;
DE   RecName: Full=Potassium voltage-gated channel subfamily C member 4;
DE   AltName: Full=KSHIIIC;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv3.4;
GN   Name=KCNC4;
DR   GuidetoPHARMACOLOGY; 551; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCND1_HUMAN             Reviewed;         647 AA.
AC   Q9NSA2; B2RCG0; O75671;
DE   RecName: Full=Potassium voltage-gated channel subfamily D member 1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv4.1;
GN   Name=KCND1;
DR   GuidetoPHARMACOLOGY; 552; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCND2_HUMAN             Reviewed;         630 AA.
AC   Q9NZV8; O95012; O95021; Q2TBD3; Q9UBY7; Q9UN98; Q9UNH9;
DE   RecName: Full=Potassium voltage-gated channel subfamily D member 2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv4.2;
GN   Name=KCND2; Synonyms=KIAA1044;
DR   GO; GO:0005250; F:A-type (transient outward) potassium channel activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; NAS:UniProtKB.
DR   GO; GO:0001508; P:action potential; TAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   KCND3_HUMAN             Reviewed;         655 AA.
AC   Q9UK17; O60576; O60577; Q14D71; Q5T0M0; Q9UH85; Q9UH86; Q9UK16;
DE   RecName: Full=Potassium voltage-gated channel subfamily D member 3;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv4.3;
GN   Name=KCND3;
DR   GO; GO:0005250; F:A-type (transient outward) potassium channel activity; IBA:RefGenome.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0086009; P:membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNE1_HUMAN             Reviewed;         129 AA.
AC   P15382; A5H1P2; Q8N709; Q91Z94;
DE   RecName: Full=Potassium voltage-gated channel subfamily E member 1;
DE   AltName: Full=Delayed rectifier potassium channel subunit IsK;
DE   AltName: Full=IKs producing slow voltage-gated potassium channel subunit beta Mink;
DE   AltName: Full=Minimal potassium channel;
GN   Name=KCNE1;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031433; F:telethonin binding; IPI:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0071468; P:cellular response to acidity; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:BHF-UCL.
DR   GO; GO:0002070; P:epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0060047; P:heart contraction; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0086009; P:membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0086011; P:membrane repolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0086013; P:membrane repolarization during cardiac muscle cell action potential; IDA:BHF-UCL.
DR   GO; GO:0090315; P:negative regulation of protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:1902259; P:regulation of delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:1901379; P:regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   KCNE2_HUMAN             Reviewed;         123 AA.
AC   Q9Y6J6; A5H1P3; D3DSF8; Q52LJ5;
DE   RecName: Full=Potassium voltage-gated channel subfamily E member 2;
DE   AltName: Full=MinK-related peptide 1;
DE   AltName: Full=Minimum potassium ion channel-related peptide 1;
DE   AltName: Full=Potassium channel subunit beta MiRP1;
GN   Name=KCNE2;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0044325; F:ion channel binding; IDA:BHF-UCL.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:1902282; F:voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IDA:BHF-UCL.
DR   GO; GO:0086009; P:membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0086011; P:membrane repolarization during action potential; IMP:BHF-UCL.
DR   GO; GO:1901800; P:positive regulation of proteasomal protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0010107; P:potassium ion import; IMP:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:1902159; P:regulation of cyclic nucleotide-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:1902259; P:regulation of delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:1901979; P:regulation of inward rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:1901379; P:regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   KCNE3_HUMAN             Reviewed;         103 AA.
AC   Q9Y6H6;
DE   RecName: Full=Potassium voltage-gated channel subfamily E member 3;
DE   AltName: Full=MinK-related peptide 2;
DE   AltName: Full=Minimum potassium ion channel-related peptide 2;
DE   AltName: Full=Potassium channel subunit beta MiRP2;
GN   Name=KCNE3;
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR   GO; GO:0043266; P:regulation of potassium ion transport; IEA:Ensembl.
//
ID   KCNE4_HUMAN             Reviewed;         170 AA.
AC   Q8WWG9; B7Z275; Q53SM4; Q96CC4;
DE   RecName: Full=Potassium voltage-gated channel subfamily E member 4;
DE   AltName: Full=MinK-related peptide 3;
DE   AltName: Full=Minimum potassium ion channel-related peptide 3;
DE   AltName: Full=Potassium channel subunit beta MiRP3;
GN   Name=KCNE4;
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
//
ID   KCNF1_HUMAN             Reviewed;         494 AA.
AC   Q9H3M0; O43527; Q585L3;
DE   RecName: Full=Potassium voltage-gated channel subfamily F member 1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv5.1;
DE   AltName: Full=kH1;
GN   Name=KCNF1;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNG1_HUMAN             Reviewed;         513 AA.
AC   Q9UIX4; A8K3S4; O43528; Q5JXL5; Q9BRC1;
DE   RecName: Full=Potassium voltage-gated channel subfamily G member 1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv6.1;
DE   AltName: Full=kH2;
GN   Name=KCNG1;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; NAS:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNG3_HUMAN             Reviewed;         436 AA.
AC   Q8TAE7; Q53SC1;
DE   RecName: Full=Potassium voltage-gated channel subfamily G member 3;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv10.1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv6.3;
GN   Name=KCNG3;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNG2_HUMAN             Reviewed;         466 AA.
AC   Q9UJ96;
DE   RecName: Full=Potassium voltage-gated channel subfamily G member 2;
DE   AltName: Full=Cardiac potassium channel subunit;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv6.2;
GN   Name=KCNG2; Synonyms=KCNF2;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNG4_HUMAN             Reviewed;         519 AA.
AC   Q8TDN1; Q96H24;
DE   RecName: Full=Potassium voltage-gated channel subfamily G member 4;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv6.4;
GN   Name=KCNG4; Synonyms=KCNG3;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH1_HUMAN             Reviewed;         989 AA.
AC   O95259; B1AQ26; O76035; Q14CL3;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 1;
DE   AltName: Full=Ether-a-go-go potassium channel 1;
DE            Short=EAG channel 1;
DE            Short=h-eag;
DE            Short=hEAG1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv10.1;
GN   Name=KCNH1; Synonyms=EAG, EAG1;
DR   GuidetoPHARMACOLOGY; 570; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007520; P:myoblast fusion; TAS:ProtInc.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH2_HUMAN             Reviewed;        1159 AA.
AC   Q12809; A5H1P7; C4PFH9; D3DX04; O75418; O75680; Q708S9; Q9BT72;
AC   Q9BUT7; Q9H3P0;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 2;
DE   AltName: Full=Eag homolog;
DE   AltName: Full=Ether-a-go-go-related gene potassium channel 1;
DE            Short=ERG-1;
DE            Short=Eag-related protein 1;
DE            Short=Ether-a-go-go-related protein 1;
DE            Short=H-ERG;
DE            Short=hERG-1;
DE            Short=hERG1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv11.1;
GN   Name=KCNH2; Synonyms=ERG, ERG1, HERG;
DR   GuidetoPHARMACOLOGY; 572; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:1902282; F:voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0035690; P:cellular response to drug; IDA:BHF-UCL.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0086011; P:membrane repolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0086013; P:membrane repolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:1902303; P:negative regulation of potassium ion export; IDA:BHF-UCL.
DR   GO; GO:1901380; P:negative regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0055075; P:potassium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0003064; P:regulation of heart rate by hormone; TAS:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:1901379; P:regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   KCNH3_HUMAN             Reviewed;        1083 AA.
AC   Q9ULD8; Q9UQ06;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 3;
DE   AltName: Full=Brain-specific eag-like channel 1;
DE            Short=BEC1;
DE   AltName: Full=Ether-a-go-go-like potassium channel 2;
DE            Short=ELK channel 2;
DE            Short=ELK2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv12.2;
GN   Name=KCNH3; Synonyms=KIAA1282;
DR   GuidetoPHARMACOLOGY; 576; -.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH4_HUMAN             Reviewed;        1017 AA.
AC   Q9UQ05;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 4;
DE   AltName: Full=Brain-specific eag-like channel 2;
DE            Short=BEC2;
DE   AltName: Full=Ether-a-go-go-like potassium channel 1;
DE            Short=ELK channel 1;
DE            Short=ELK1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv12.3;
GN   Name=KCNH4;
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH5_HUMAN             Reviewed;         988 AA.
AC   Q8NCM2; C9JP98;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 5;
DE   AltName: Full=Ether-a-go-go potassium channel 2;
DE            Short=hEAG2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv10.2;
GN   Name=KCNH5; Synonyms=EAG2;
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IDA:MGI.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH6_HUMAN             Reviewed;         994 AA.
AC   Q9H252; Q9BRD7;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 6;
DE   AltName: Full=Ether-a-go-go-related gene potassium channel 2;
DE            Short=ERG-2;
DE            Short=Eag-related protein 2;
DE            Short=Ether-a-go-go-related protein 2;
DE            Short=hERG-2;
DE            Short=hERG2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv11.2;
GN   Name=KCNH6; Synonyms=ERG2;
DR   GuidetoPHARMACOLOGY; 573; -.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH7_HUMAN             Reviewed;        1196 AA.
AC   Q9NS40; Q53QU4; Q53TB7; Q53TP9; Q8IV15;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 7;
DE   AltName: Full=Ether-a-go-go-related gene potassium channel 3;
DE            Short=ERG-3;
DE            Short=Eag-related protein 3;
DE            Short=Ether-a-go-go-related protein 3;
DE            Short=hERG-3;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv11.3;
GN   Name=KCNH7; Synonyms=ERG3;
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNH8_HUMAN             Reviewed;        1107 AA.
AC   Q96L42; Q59GQ6;
DE   RecName: Full=Potassium voltage-gated channel subfamily H member 8;
DE   AltName: Full=ELK1;
DE            Short=hElk1;
DE   AltName: Full=Ether-a-go-go-like potassium channel 3;
DE            Short=ELK channel 3;
DE            Short=ELK3;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv12.1;
GN   Name=KCNH8;
DR   GuidetoPHARMACOLOGY; 575; -.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNJ1_HUMAN             Reviewed;         391 AA.
AC   P48048; B2RMR4; Q6LD67;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 1;
DE   AltName: Full=ATP-regulated potassium channel ROM-K;
DE   AltName: Full=Inward rectifier K(+) channel Kir1.1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 1;
GN   Name=KCNJ1; Synonyms=ROMK1;
DR   GuidetoPHARMACOLOGY; 429; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0072358; P:cardiovascular system development; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:1900128; P:regulation of G-protein activated inward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0070294; P:renal sodium ion absorption; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
//
ID   KCNJ2_HUMAN             Reviewed;         427 AA.
AC   P63252; O15110; P48049;
DE   RecName: Full=Inward rectifier potassium channel 2;
DE   AltName: Full=Cardiac inward rectifier potassium channel;
DE   AltName: Full=Inward rectifier K(+) channel Kir2.1;
DE            Short=IRK-1;
DE            Short=hIRK1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 2;
GN   Name=KCNJ2; Synonyms=IRK1;
DR   GuidetoPHARMACOLOGY; 430; -.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0086008; F:voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0030007; P:cellular potassium ion homeostasis; TAS:BHF-UCL.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0015693; P:magnesium ion transport; IEA:Ensembl.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; TAS:BHF-UCL.
DR   GO; GO:0086011; P:membrane repolarization during action potential; IMP:BHF-UCL.
DR   GO; GO:0086013; P:membrane repolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0010107; P:potassium ion import; IDA:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0060075; P:regulation of resting membrane potential; TAS:BHF-UCL.
DR   GO; GO:0014861; P:regulation of skeletal muscle contraction via regulation of action potential; IMP:BHF-UCL.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; IMP:BHF-UCL.
DR   GO; GO:0090076; P:relaxation of skeletal muscle; IMP:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNJ3_HUMAN             Reviewed;         501 AA.
AC   P48549; B4DEW7; Q8TBI0;
DE   RecName: Full=G protein-activated inward rectifier potassium channel 1;
DE            Short=GIRK-1;
DE   AltName: Full=Inward rectifier K(+) channel Kir3.1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 3;
GN   Name=KCNJ3; Synonyms=GIRK1;
DR   GuidetoPHARMACOLOGY; 434; -.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNJ4_HUMAN             Reviewed;         445 AA.
AC   P48050; Q14D44;
DE   RecName: Full=Inward rectifier potassium channel 4;
DE   AltName: Full=HIRK2;
DE   AltName: Full=HRK1;
DE   AltName: Full=Hippocampal inward rectifier;
DE            Short=HIR;
DE   AltName: Full=Inward rectifier K(+) channel Kir2.3;
DE            Short=IRK-3;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 4;
GN   Name=KCNJ4; Synonyms=IRK3;
DR   GuidetoPHARMACOLOGY; 432; -.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNJ5_HUMAN             Reviewed;         419 AA.
AC   P48544; B2R744; Q6DK13; Q6DK14; Q92807;
DE   RecName: Full=G protein-activated inward rectifier potassium channel 4;
DE            Short=GIRK-4;
DE   AltName: Full=Cardiac inward rectifier;
DE            Short=CIR;
DE   AltName: Full=Heart KATP channel;
DE   AltName: Full=Inward rectifier K(+) channel Kir3.4;
DE            Short=IRK-4;
DE   AltName: Full=KATP-1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 5;
GN   Name=KCNJ5; Synonyms=GIRK4;
DR   GuidetoPHARMACOLOGY; 437; -.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNJ6_HUMAN             Reviewed;         423 AA.
AC   P48051; Q3MJ74; Q53WW6;
DE   RecName: Full=G protein-activated inward rectifier potassium channel 2;
DE            Short=GIRK-2;
DE   AltName: Full=BIR1;
DE   AltName: Full=Inward rectifier K(+) channel Kir3.2;
DE   AltName: Full=KATP-2;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 6;
GN   Name=KCNJ6; Synonyms=GIRK2, KATP2, KCNJ7;
DR   GuidetoPHARMACOLOGY; 435; -.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNJ8_HUMAN             Reviewed;         424 AA.
AC   Q15842; O00657;
DE   RecName: Full=ATP-sensitive inward rectifier potassium channel 8;
DE   AltName: Full=Inward rectifier K(+) channel Kir6.1;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 8;
DE   AltName: Full=uKATP-1;
GN   Name=KCNJ8;
DR   GuidetoPHARMACOLOGY; 441; -.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0010107; P:potassium ion import; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   KCNJ9_HUMAN             Reviewed;         393 AA.
AC   Q92806; Q5JW75;
DE   RecName: Full=G protein-activated inward rectifier potassium channel 3;
DE            Short=GIRK-3;
DE   AltName: Full=Inward rectifier K(+) channel Kir3.3;
DE   AltName: Full=Potassium channel, inwardly rectifying subfamily J member 9;
GN   Name=KCNJ9; Synonyms=GIRK3;
DR   GuidetoPHARMACOLOGY; 436; -.
DR   GO; GO:0015467; F:G-protein activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK1_HUMAN             Reviewed;         336 AA.
AC   O00180; Q13307; Q5T5E8;
DE   RecName: Full=Potassium channel subfamily K member 1;
DE   AltName: Full=Inward rectifying potassium channel protein TWIK-1;
DE   AltName: Full=Potassium channel KCNO1;
GN   Name=KCNK1; Synonyms=HOHO1, KCNO1, TWIK1;
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK2_HUMAN             Reviewed;         426 AA.
AC   O95069; A1Z1V3; A8K618; B2RCS4; B7ZL56; D3DTA5; Q5DP47; Q5DP48;
AC   Q9NRT2; Q9UNE3;
DE   RecName: Full=Potassium channel subfamily K member 2;
DE   AltName: Full=Outward rectifying potassium channel protein TREK-1;
DE   AltName: Full=TREK-1 K(+) channel subunit;
DE   AltName: Full=Two pore domain potassium channel TREK-1;
DE   AltName: Full=Two pore potassium channel TPKC1;
GN   Name=KCNK2; Synonyms=TREK, TREK1;
DR   GuidetoPHARMACOLOGY; 514; -.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK3_HUMAN             Reviewed;         394 AA.
AC   O14649; Q53SU2;
DE   RecName: Full=Potassium channel subfamily K member 3;
DE   AltName: Full=Acid-sensitive potassium channel protein TASK-1;
DE   AltName: Full=TWIK-related acid-sensitive K(+) channel 1;
DE   AltName: Full=Two pore potassium channel KT3.1;
DE            Short=Two pore K(+) channel KT3.1;
GN   Name=KCNK3; Synonyms=TASK, TASK1;
DR   GuidetoPHARMACOLOGY; 515; -.
DR   GO; GO:0005216; F:ion channel activity; IMP:UniProt.
DR   GO; GO:0005252; F:open rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0022841; F:potassium ion leak channel activity; IDA:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProt.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IMP:UniProt.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK4_HUMAN             Reviewed;         393 AA.
AC   Q9NYG8; B5TJL1; Q96T94;
DE   RecName: Full=Potassium channel subfamily K member 4;
DE   AltName: Full=TWIK-related arachidonic acid-stimulated potassium channel protein;
DE            Short=TRAAK;
DE   AltName: Full=Two pore potassium channel KT4.1;
DE            Short=Two pore K(+) channel KT4.1;
GN   Name=KCNK4; Synonyms=TRAAK;
DR   GuidetoPHARMACOLOGY; 516; -.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK5_HUMAN             Reviewed;         499 AA.
AC   O95279; B2RAQ6; B5TJL2; Q5VV76;
DE   RecName: Full=Potassium channel subfamily K member 5;
DE   AltName: Full=Acid-sensitive potassium channel protein TASK-2;
DE   AltName: Full=TWIK-related acid-sensitive K(+) channel 2;
GN   Name=KCNK5; Synonyms=TASK2;
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
//
ID   KCNK7_HUMAN             Reviewed;         307 AA.
AC   Q9Y2U2; Q3SYI2; Q9Y2U3; Q9Y2U4;
DE   RecName: Full=Potassium channel subfamily K member 7;
GN   Name=KCNK7;
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK6_HUMAN             Reviewed;         313 AA.
AC   Q9Y257; Q9HB47;
DE   RecName: Full=Potassium channel subfamily K member 6;
DE   AltName: Full=Inward rectifying potassium channel protein TWIK-2;
DE   AltName: Full=TWIK-originated similarity sequence;
GN   Name=KCNK6; Synonyms=TOSS, TWIK2;
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0003085; P:negative regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0060075; P:regulation of resting membrane potential; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNK9_HUMAN             Reviewed;         374 AA.
AC   Q9NPC2; Q2M290; Q540F2;
DE   RecName: Full=Potassium channel subfamily K member 9;
DE   AltName: Full=Acid-sensitive potassium channel protein TASK-3;
DE   AltName: Full=TWIK-related acid-sensitive K(+) channel 3;
DE   AltName: Full=Two pore potassium channel KT3.2;
DE            Short=Two pore K(+) channel KT3.2;
GN   Name=KCNK9; Synonyms=TASK3;
DR   GuidetoPHARMACOLOGY; 520; -.
DR   GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNKA_HUMAN             Reviewed;         538 AA.
AC   P57789; B2R8T4; B2RCT3; B5TJL4; Q6B014; Q8TDK7; Q8TDK8; Q9HB59;
DE   RecName: Full=Potassium channel subfamily K member 10;
DE   AltName: Full=Outward rectifying potassium channel protein TREK-2;
DE   AltName: Full=TREK-2 K(+) channel subunit;
GN   Name=KCNK10; Synonyms=TREK2;
DR   GuidetoPHARMACOLOGY; 521; -.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   KCNKC_HUMAN             Reviewed;         430 AA.
AC   Q9HB15;
DE   RecName: Full=Potassium channel subfamily K member 12;
DE   AltName: Full=Tandem pore domain halothane-inhibited potassium channel 2;
DE            Short=THIK-2;
GN   Name=KCNK12;
DR   GuidetoPHARMACOLOGY; 522; -.
DR   GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
//
ID   KCNKD_HUMAN             Reviewed;         408 AA.
AC   Q9HB14; B5TJL8; Q96E79;
DE   RecName: Full=Potassium channel subfamily K member 13;
DE   AltName: Full=Tandem pore domain halothane-inhibited potassium channel 1;
DE            Short=THIK-1;
GN   Name=KCNK13;
DR   GuidetoPHARMACOLOGY; 523; -.
DR   GO; GO:0005267; F:potassium channel activity; TAS:Reactome.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNKF_HUMAN             Reviewed;         330 AA.
AC   Q9H427; Q52LL3; Q9HBC8;
DE   RecName: Full=Potassium channel subfamily K member 15;
DE   AltName: Full=Acid-sensitive potassium channel protein TASK-5;
DE   AltName: Full=TWIK-related acid-sensitive K(+) channel 5;
DE   AltName: Full=Two pore potassium channel KT3.3;
DE            Short=Two pore K(+) channel KT3.3;
GN   Name=KCNK15; Synonyms=TASK5;
DR   GuidetoPHARMACOLOGY; 524; -.
DR   GO; GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
//
ID   KCNKG_HUMAN             Reviewed;         309 AA.
AC   Q96T55; B5TJL9; Q2M2N9; Q5TCF3; Q6X6Z3; Q6X6Z4; Q6X6Z5; Q9H591;
DE   RecName: Full=Potassium channel subfamily K member 16;
DE   AltName: Full=2P domain potassium channel Talk-1;
DE   AltName: Full=TWIK-related alkaline pH-activated K(+) channel 1;
DE            Short=TALK-1;
GN   Name=KCNK16; Synonyms=TALK1;
DR   GO; GO:0005267; F:potassium channel activity; IDA:MGI.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; IDA:MGI.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNKH_HUMAN             Reviewed;         332 AA.
AC   Q96T54; E9PB46; Q5TCF4; Q8TAW4; Q9BXD1; Q9H592;
DE   RecName: Full=Potassium channel subfamily K member 17;
DE   AltName: Full=2P domain potassium channel Talk-2;
DE   AltName: Full=Acid-sensitive potassium channel protein TASK-4;
DE   AltName: Full=TWIK-related acid-sensitive K(+) channel 4;
DE   AltName: Full=TWIK-related alkaline pH-activated K(+) channel 2;
DE            Short=TALK-2;
GN   Name=KCNK17; Synonyms=TALK2, TASK4; ORFNames=UNQ5816/PRO19634;
DR   GO; GO:0005267; F:potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNKI_HUMAN             Reviewed;         384 AA.
AC   Q7Z418; Q5SQQ8;
DE   RecName: Full=Potassium channel subfamily K member 18;
DE   AltName: Full=TWIK-related individual potassium channel;
DE   AltName: Full=TWIK-related spinal cord potassium channel;
GN   Name=KCNK18; Synonyms=TRESK, TRIK;
DR   GuidetoPHARMACOLOGY; 527; -.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IEA:Ensembl.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0005267; F:potassium channel activity; TAS:Reactome.
DR   GO; GO:0071467; P:cellular response to pH; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0006813; P:potassium ion transport; IDA:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNN1_HUMAN             Reviewed;         543 AA.
AC   Q92952; Q5KR10; Q6DJU4;
DE   RecName: Full=Small conductance calcium-activated potassium channel protein 1;
DE            Short=SK1;
DE            Short=SKCa 1;
DE            Short=SKCa1;
DE   AltName: Full=KCa2.1;
GN   Name=KCNN1; Synonyms=SK;
DR   GuidetoPHARMACOLOGY; 381; -.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005516; F:calmodulin binding; IBA:RefGenome.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNN2_HUMAN             Reviewed;         579 AA.
AC   Q9H2S1; A6NF94; Q0VFZ4; Q6PJI0; Q6X2Y2;
DE   RecName: Full=Small conductance calcium-activated potassium channel protein 2;
DE            Short=SK2;
DE            Short=SKCa 2;
DE            Short=SKCa2;
DE   AltName: Full=KCa2.2;
GN   Name=KCNN2;
DR   GuidetoPHARMACOLOGY; 382; -.
DR   GO; GO:0051393; F:alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; TAS:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006813; P:potassium ion transport; NAS:UniProtKB.
DR   GO; GO:1901379; P:regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNN3_HUMAN             Reviewed;         736 AA.
AC   Q9UGI6; B1ANX0; O43517; Q86VF9; Q8WXG7;
DE   RecName: Full=Small conductance calcium-activated potassium channel protein 3;
DE            Short=SK3;
DE            Short=SKCa 3;
DE            Short=SKCa3;
DE   AltName: Full=KCa2.3;
GN   Name=KCNN3; Synonyms=K3;
DR   GuidetoPHARMACOLOGY; 383; -.
DR   GO; GO:0005516; F:calmodulin binding; IBA:RefGenome.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNN4_HUMAN             Reviewed;         427 AA.
AC   O15554; Q53XR4;
DE   RecName: Full=Intermediate conductance calcium-activated potassium channel protein 4;
DE            Short=SK4;
DE            Short=SKCa 4;
DE            Short=SKCa4;
DE   AltName: Full=IKCa1;
DE            Short=IK1;
DE   AltName: Full=KCa3.1;
DE   AltName: Full=KCa4;
DE   AltName: Full=Putative Gardos channel;
GN   Name=KCNN4; Synonyms=IK1, IKCA1, KCA4, SK4;
DR   GuidetoPHARMACOLOGY; 384; -.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; IBA:RefGenome.
DR   GO; GO:0022894; F:Intermediate conductance calcium-activated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:0006884; P:cell volume homeostasis; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0045332; P:phospholipid translocation; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IEA:Ensembl.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0046541; P:saliva secretion; IEA:Ensembl.
DR   GO; GO:0030322; P:stabilization of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNQ1_HUMAN             Reviewed;         676 AA.
AC   P51787; O00347; O60607; O94787; Q7Z6G9; Q92960; Q9UMN8; Q9UMN9;
DE   RecName: Full=Potassium voltage-gated channel subfamily KQT member 1;
DE   AltName: Full=IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1;
DE   AltName: Full=KQT-like 1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv7.1;
GN   Name=KCNQ1; Synonyms=KCNA8, KCNA9, KVLQT1;
DR   GuidetoPHARMACOLOGY; 560; -.
DR   GO; GO:0005516; F:calmodulin binding; IDA:BHF-UCL.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IDA:BHF-UCL.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IDA:BHF-UCL.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IDA:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0086089; F:voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:0086008; F:voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:1902282; F:voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization; IMP:BHF-UCL.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0072358; P:cardiovascular system development; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:BHF-UCL.
DR   GO; GO:0035690; P:cellular response to drug; IDA:BHF-UCL.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; TAS:BHF-UCL.
DR   GO; GO:0016458; P:gene silencing; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0086011; P:membrane repolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0086013; P:membrane repolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0060454; P:positive regulation of gastric acid secretion; IEA:Ensembl.
DR   GO; GO:1901381; P:positive regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0071435; P:potassium ion export; IDA:BHF-UCL.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060372; P:regulation of atrial cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IC:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   KCNQ2_HUMAN             Reviewed;         872 AA.
AC   O43526; O43796; O75580; O95845; Q4VXP4; Q4VXR6; Q5VYT8; Q96J59;
AC   Q99454;
DE   RecName: Full=Potassium voltage-gated channel subfamily KQT member 2;
DE   AltName: Full=KQT-like 2;
DE   AltName: Full=Neuroblastoma-specific potassium channel subunit alpha KvLQT2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv7.2;
GN   Name=KCNQ2;
DR   GuidetoPHARMACOLOGY; 561; -.
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   KCNQ3_HUMAN             Reviewed;         872 AA.
AC   O43525; B4DJY4; E7EQ89;
DE   RecName: Full=Potassium voltage-gated channel subfamily KQT member 3;
DE   AltName: Full=KQT-like 3;
DE   AltName: Full=Potassium channel subunit alpha KvLQT3;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv7.3;
GN   Name=KCNQ3;
DR   GuidetoPHARMACOLOGY; 562; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNQ4_HUMAN             Reviewed;         695 AA.
AC   P56696; O96025;
DE   RecName: Full=Potassium voltage-gated channel subfamily KQT member 4;
DE   AltName: Full=KQT-like 4;
DE   AltName: Full=Potassium channel subunit alpha KvLQT4;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv7.4;
GN   Name=KCNQ4;
DR   GuidetoPHARMACOLOGY; 563; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:ProtInc.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNQ5_HUMAN             Reviewed;         932 AA.
AC   Q9NR82; B4DS33; B5MC83; B7ZL37; F5GZV0; Q17RE1; Q5VVP3; Q86W40;
AC   Q9NRN0; Q9NYA6;
DE   RecName: Full=Potassium voltage-gated channel subfamily KQT member 5;
DE   AltName: Full=KQT-like 5;
DE   AltName: Full=Potassium channel subunit alpha KvLQT5;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv7.5;
GN   Name=KCNQ5;
DR   GuidetoPHARMACOLOGY; 564; -.
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006461; P:protein complex assembly; NAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNRG_HUMAN             Reviewed;         272 AA.
AC   Q8N5I3; A2A2X9; Q0P6D0; Q8IU75; Q8N3Q9;
DE   RecName: Full=Potassium channel regulatory protein;
DE            Short=Potassium channel regulator;
DE   AltName: Full=Protein CLLD4;
GN   Name=KCNRG; Synonyms=CLLD4;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCNS1_HUMAN             Reviewed;         526 AA.
AC   Q96KK3; A2RUL9; B7ZM31; O43652; Q6DJU6;
DE   RecName: Full=Potassium voltage-gated channel subfamily S member 1;
DE   AltName: Full=Delayed-rectifier K(+) channel alpha subunit 1;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv9.1;
GN   Name=KCNS1;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; TAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNS2_HUMAN             Reviewed;         477 AA.
AC   Q9ULS6; A8KAN1;
DE   RecName: Full=Potassium voltage-gated channel subfamily S member 2;
DE   AltName: Full=Delayed-rectifier K(+) channel alpha subunit 2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv9.2;
GN   Name=KCNS2; Synonyms=KIAA1144;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNS3_HUMAN             Reviewed;         491 AA.
AC   Q9BQ31; D6W520; O43651; Q4ZFY1; Q96B56;
DE   RecName: Full=Potassium voltage-gated channel subfamily S member 3;
DE   AltName: Full=Delayed-rectifier K(+) channel alpha subunit 3;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv9.3;
GN   Name=KCNS3;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; TAS:ProtInc.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNT1_HUMAN             Reviewed;        1230 AA.
AC   Q5JUK3; B7ZVY4; B9EGP2; Q9P2C5;
DE   RecName: Full=Potassium channel subfamily T member 1;
DE   AltName: Full=KCa4.1;
GN   Name=KCNT1; Synonyms=KIAA1422;
DR   GuidetoPHARMACOLOGY; 385; -.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
//
ID   KCNT2_HUMAN             Reviewed;        1135 AA.
AC   Q6UVM3; Q3SY59; Q5VTN1; Q6ZMT3;
DE   RecName: Full=Potassium channel subfamily T member 2;
DE   AltName: Full=Sequence like an intermediate conductance potassium channel subunit;
DE   AltName: Full=Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1;
GN   Name=KCNT2; Synonyms=SLICK;
DR   GuidetoPHARMACOLOGY; 386; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
//
ID   KCNU1_HUMAN             Reviewed;        1149 AA.
AC   A8MYU2;
DE   RecName: Full=Potassium channel subfamily U member 1;
DE   AltName: Full=Calcium-activated potassium channel subunit alpha-3;
DE   AltName: Full=Calcium-activated potassium channel, subfamily M subunit alpha-3;
DE   AltName: Full=KCa5;
DE   AltName: Full=Slowpoke homolog 3;
GN   Name=KCNU1; Synonyms=KCNMA3, KCNMC1, SLO3;
DR   GuidetoPHARMACOLOGY; 387; -.
DR   GO; GO:0060072; F:large conductance calcium-activated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0005267; F:potassium channel activity; TAS:Reactome.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:RefGenome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
DR   GO; GO:0035036; P:sperm-egg recognition; TAS:Reactome.
//
ID   KCNV1_HUMAN             Reviewed;         500 AA.
AC   Q6PIU1; Q9UHJ4;
DE   RecName: Full=Potassium voltage-gated channel subfamily V member 1;
DE   AltName: Full=Neuronal potassium channel alpha subunit HNKA;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv8.1;
GN   Name=KCNV1;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0008200; F:ion channel inhibitor activity; TAS:ProtInc.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0006813; P:potassium ion transport; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCNV2_HUMAN             Reviewed;         545 AA.
AC   Q8TDN2; Q5T6X0;
DE   RecName: Full=Potassium voltage-gated channel subfamily V member 2;
DE   AltName: Full=Voltage-gated potassium channel subunit Kv8.2;
GN   Name=KCNV2;
DR   GO; GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KCP3_HUMAN              Reviewed;         240 AA.
AC   Q53RY4; B7ZL49; Q6UW42; Q8IWS5;
DE   RecName: Full=Keratinocyte-associated protein 3;
DE            Short=KCP-3;
GN   Name=KRTCAP3; Synonyms=KCP3; ORFNames=UNQ3066/PRO9898;
//
ID   KCP_HUMAN               Reviewed;        1503 AA.
AC   Q6ZWJ8; Q8NBE0;
DE   RecName: Full=Kielin/chordin-like protein;
DE   AltName: Full=Cysteine-rich BMP regulator 2;
DE   AltName: Full=Cysteine-rich motor neuron 2 protein;
DE            Short=CRIM-2;
DE   AltName: Full=Kielin/chordin-like protein 1;
DE            Short=KCP-1;
DE   Flags: Precursor;
GN   Name=KCP; Synonyms=CRIM2, KCP1;
//
ID   KCQ1D_HUMAN             Reviewed;          68 AA.
AC   Q9H478;
DE   RecName: Full=KCNQ1 downstream neighbor protein;
DE   AltName: Full=Beckwith-Wiedemann region transcript protein;
GN   Name=KCNQ1DN; Synonyms=BWRT;
//
ID   KCRB_HUMAN              Reviewed;         381 AA.
AC   P12277; A8K236; B2R5R4; Q2LE07; Q6FG40; Q9UC66;
DE   RecName: Full=Creatine kinase B-type;
DE            EC=2.7.3.2;
DE   AltName: Full=B-CK;
DE   AltName: Full=Creatine kinase B chain;
GN   Name=CKB; Synonyms=CKBB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030644; P:cellular chloride ion homeostasis; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   KCRM_HUMAN              Reviewed;         381 AA.
AC   P06732; Q96QL9;
DE   RecName: Full=Creatine kinase M-type;
DE            EC=2.7.3.2;
DE   AltName: Full=Creatine kinase M chain;
DE   AltName: Full=M-CK;
DE   Contains:
DE     RecName: Full=Creatine kinase M-type, N-terminally processed;
GN   Name=CKM; Synonyms=CKMM;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:0046314; P:phosphocreatine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KCRS_HUMAN              Reviewed;         419 AA.
AC   P17540; Q6ICS8; Q8N1E1;
DE   RecName: Full=Creatine kinase S-type, mitochondrial;
DE            EC=2.7.3.2;
DE   AltName: Full=Basic-type mitochondrial creatine kinase;
DE            Short=Mib-CK;
DE   AltName: Full=Sarcomeric mitochondrial creatine kinase;
DE            Short=S-MtCK;
DE   Flags: Precursor;
GN   Name=CKMT2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KCRU_HUMAN              Reviewed;         417 AA.
AC   P12532; B4DIT8; B7ZA09; Q0VAM3; Q32NF6; Q53FC4;
DE   RecName: Full=Creatine kinase U-type, mitochondrial;
DE            EC=2.7.3.2;
DE   AltName: Full=Acidic-type mitochondrial creatine kinase;
DE            Short=Mia-CK;
DE   AltName: Full=Ubiquitous mitochondrial creatine kinase;
DE            Short=U-MtCK;
DE   Flags: Precursor;
GN   Name=CKMT1A; Synonyms=CKMT;
GN   and
GN   Name=CKMT1B; Synonyms=CKMT;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004111; F:creatine kinase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KCT2_HUMAN              Reviewed;         265 AA.
AC   Q8NC54; B2RD10; D3DQ92; Q9NRG2;
DE   RecName: Full=Keratinocyte-associated transmembrane protein 2;
DE   Flags: Precursor;
GN   Name=KCT2; Synonyms=C5orf15; ORFNames=HTGN29;
//
ID   KCTD1_HUMAN             Reviewed;         257 AA.
AC   Q719H9; A8K1F5;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD1;
DE   AltName: Full=Potassium channel tetramerization domain-containing protein 1;
GN   Name=KCTD1; Synonyms=C18orf5;
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KCTD3_HUMAN             Reviewed;         815 AA.
AC   Q9Y597; A0AV15; D3DTA6; Q49AG7; Q504Q9; Q6PJN6; Q8ND58; Q8NDJ0;
AC   Q8WX16;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD3;
DE   AltName: Full=Renal carcinoma antigen NY-REN-45;
GN   Name=KCTD3;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCTD2_HUMAN             Reviewed;         263 AA.
AC   Q14681;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD2;
DE   AltName: Full=Potassium channel tetramerization domain-containing protein 2;
GN   Name=KCTD2; Synonyms=KIAA0176;
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCTD4_HUMAN             Reviewed;         259 AA.
AC   Q8WVF5; Q5W0P9;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD4;
GN   Name=KCTD4;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCTD5_HUMAN             Reviewed;         234 AA.
AC   Q9NXV2; D3DU96;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD5;
GN   Name=KCTD5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KCTD6_HUMAN             Reviewed;         237 AA.
AC   Q8NC69; B3KNI5; Q8NBS6; Q8TCA6;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD6;
GN   Name=KCTD6;
DR   GO; GO:0030506; F:ankyrin binding; IDA:MGI.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCTD7_HUMAN             Reviewed;         289 AA.
AC   Q96MP8; A4D2M4; Q8IVR0;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD7;
GN   Name=KCTD7;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCTD8_HUMAN             Reviewed;         473 AA.
AC   Q6ZWB6; A2RU39;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD8;
GN   Name=KCTD8;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
//
ID   KCTD9_HUMAN             Reviewed;         389 AA.
AC   Q7L273; Q6NUM8; Q9NXV4;
DE   RecName: Full=BTB/POZ domain-containing protein KCTD9;
GN   Name=KCTD9;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   KCY_HUMAN               Reviewed;         196 AA.
AC   P30085; B4DPU7; E9PGI8; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2;
DE   RecName: Full=UMP-CMP kinase;
DE            EC=2.7.4.14;
DE   AltName: Full=Deoxycytidylate kinase;
DE            Short=CK;
DE            Short=dCMP kinase;
DE   AltName: Full=Nucleoside-diphosphate kinase;
DE            EC=2.7.4.6;
DE   AltName: Full=Uridine monophosphate/cytidine monophosphate kinase;
DE            Short=UMP/CMP kinase;
DE            Short=UMP/CMPK;
GN   Name=CMPK1; Synonyms=CMK, CMPK, UCK, UMK, UMPK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004127; F:cytidylate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0033862; F:UMP kinase activity; IEA:Ensembl.
DR   GO; GO:0004849; F:uridine kinase activity; TAS:ProtInc.
DR   GO; GO:0046705; P:CDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006240; P:dCDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006227; P:dUDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006165; P:nucleoside diphosphate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0022602; P:ovulation cycle process; IEA:Ensembl.
DR   GO; GO:0018963; P:phthalate metabolic process; IEA:Ensembl.
DR   GO; GO:0009220; P:pyrimidine ribonucleotide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006225; P:UDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006222; P:UMP biosynthetic process; TAS:GOC.
//
ID   KDEL1_HUMAN             Reviewed;         502 AA.
AC   Q6UW63; Q53HL3; Q9BVD2;
DE   RecName: Full=KDEL motif-containing protein 1;
DE   AltName: Full=Endoplasmic reticulum resident protein 58;
DE            Short=ER protein 58;
DE            Short=ERp58;
DE   Flags: Precursor;
GN   Name=KDELC1; Synonyms=EP58; ORFNames=UNQ1910/PRO4357;
//
ID   KDEL2_HUMAN             Reviewed;         507 AA.
AC   Q7Z4H8; Q6UWW2; Q6ZUM9; Q8N7L8; Q8NE24;
DE   RecName: Full=KDEL motif-containing protein 2;
DE   Flags: Precursor;
GN   Name=KDELC2; ORFNames=UNQ1904/PRO4350;
//
ID   KDIS_HUMAN              Reviewed;        1771 AA.
AC   Q9ULH0; A1L4N4; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42;
DE   RecName: Full=Kinase D-interacting substrate of 220 kDa;
DE   AltName: Full=Ankyrin repeat-rich membrane-spanning protein;
GN   Name=KIDINS220; Synonyms=ARMS, KIAA1250;
DR   GO; GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0016482; P:cytoplasmic transport; ISS:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0038180; P:nerve growth factor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
//
ID   KDM1A_HUMAN             Reviewed;         852 AA.
AC   O60341; A8MWP9; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3;
AC   Q96AW4;
DE   RecName: Full=Lysine-specific histone demethylase 1A;
DE            EC=1.-.-.-;
DE   AltName: Full=BRAF35-HDAC complex protein BHC110;
DE   AltName: Full=Flavin-containing amine oxidase domain-containing protein 2;
GN   Name=KDM1A; Synonyms=AOF2, KDM1, KIAA0601, LSD1;
DR   GuidetoPHARMACOLOGY; 2669; -.
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0032451; F:demethylase activity; IMP:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0032452; F:histone demethylase activity; IDA:BHF-UCL.
DR   GO; GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:UniProtKB.
DR   GO; GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:UniProtKB.
DR   GO; GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0043426; F:MRF binding; IDA:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0030851; P:granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0034720; P:histone H3-K4 demethylation; IDA:UniProtKB.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0055001; P:muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IC:BHF-UCL.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:0051572; P:negative regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0051573; P:negative regulation of histone H3-K9 methylation; IEA:Ensembl.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0046886; P:positive regulation of hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006482; P:protein demethylation; IMP:BHF-UCL.
DR   GO; GO:0010725; P:regulation of primitive erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM1B_HUMAN             Reviewed;         822 AA.
AC   Q8NB78; A2A2C5; A2A2C6; Q5TGV3; Q6AI15; Q6ZUU4; Q8N258; Q96EL7;
DE   RecName: Full=Lysine-specific histone demethylase 1B;
DE            EC=1.-.-.-;
DE   AltName: Full=Flavin-containing amine oxidase domain-containing protein 1;
DE   AltName: Full=Lysine-specific histone demethylase 2;
GN   Name=KDM1B; Synonyms=AOF1, C6orf193, LSD2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.
DR   GO; GO:0034649; F:histone demethylase activity (H3-monomethyl-K4 specific); ISS:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; IEA:Ensembl.
DR   GO; GO:0034720; P:histone H3-K4 demethylation; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0044030; P:regulation of DNA methylation; ISS:UniProtKB.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM2A_HUMAN             Reviewed;        1162 AA.
AC   Q9Y2K7; D4QA03; E9PIL6; I3VM55; Q49A21; Q4G0M3; Q69YY8; Q9BVH5;
AC   Q9H7H5; Q9UK66;
DE   RecName: Full=Lysine-specific demethylase 2A;
DE            EC=1.14.11.27;
DE   AltName: Full=CXXC-type zinc finger protein 8;
DE   AltName: Full=F-box and leucine-rich repeat protein 11;
DE   AltName: Full=F-box protein FBL7;
DE   AltName: Full=F-box protein Lilina;
DE   AltName: Full=F-box/LRR-repeat protein 11;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 1A;
DE   AltName: Full=[Histone-H3]-lysine-36 demethylase 1A;
GN   Name=KDM2A; Synonyms=CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004;
DR   GuidetoPHARMACOLOGY; 2671; -.
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:UniProtKB-EC.
DR   GO; GO:0045322; F:unmethylated CpG binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070544; P:histone H3-K36 demethylation; IMP:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM2B_HUMAN             Reviewed;        1336 AA.
AC   Q8NHM5; A8MRS1; Q8NCI2; Q96HC7; Q96SL0; Q96T03; Q9NS96; Q9UF75;
DE   RecName: Full=Lysine-specific demethylase 2B;
DE            EC=1.14.11.27;
DE   AltName: Full=CXXC-type zinc finger protein 2;
DE   AltName: Full=F-box and leucine-rich repeat protein 10;
DE   AltName: Full=F-box protein FBL10;
DE   AltName: Full=F-box/LRR-repeat protein 10;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 1B;
DE   AltName: Full=Jumonji domain-containing EMSY-interactor methyltransferase motif protein;
DE            Short=Protein JEMMA;
DE   AltName: Full=Protein-containing CXXC domain 2;
DE   AltName: Full=[Histone-H3]-lysine-36 demethylase 1B;
GN   Name=KDM2B; Synonyms=CXXC2, FBL10, FBXL10, JHDM1B, PCCX2;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0032452; F:histone demethylase activity; TAS:BHF-UCL.
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030900; P:forebrain development; ISS:BHF-UCL.
DR   GO; GO:0021592; P:fourth ventricle development; ISS:BHF-UCL.
DR   GO; GO:0030902; P:hindbrain development; ISS:BHF-UCL.
DR   GO; GO:0016577; P:histone demethylation; TAS:GOC.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0021993; P:initiation of neural tube closure; ISS:BHF-UCL.
DR   GO; GO:0021670; P:lateral ventricle development; ISS:BHF-UCL.
DR   GO; GO:0030901; P:midbrain development; ISS:BHF-UCL.
DR   GO; GO:0021555; P:midbrain-hindbrain boundary morphogenesis; ISS:BHF-UCL.
DR   GO; GO:2000178; P:negative regulation of neural precursor cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; ISS:BHF-UCL.
DR   GO; GO:0021678; P:third ventricle development; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM3A_HUMAN             Reviewed;        1321 AA.
AC   Q9Y4C1; D6W5M3; Q53S72; Q68D47; Q68UT9; Q6N050; Q8IY08;
DE   RecName: Full=Lysine-specific demethylase 3A;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 2A;
DE   AltName: Full=Jumonji domain-containing protein 1A;
GN   Name=KDM3A; Synonyms=JHDM2A, JMJD1, JMJD1A, KIAA0742, TSGA;
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IMP:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046293; P:formaldehyde biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IDA:UniProtKB.
DR   GO; GO:0036123; P:histone H3-K9 dimethylation; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051573; P:negative regulation of histone H3-K9 methylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0007290; P:spermatid nucleus elongation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM3B_HUMAN             Reviewed;        1761 AA.
AC   Q7LBC6; A6H8X7; Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0;
DE   RecName: Full=Lysine-specific demethylase 3B;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 2B;
DE   AltName: Full=Jumonji domain-containing protein 1B;
DE   AltName: Full=Nuclear protein 5qNCA;
GN   Name=KDM3B; Synonyms=C5orf7, JHDM2B, JMJD1B, KIAA1082;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM4A_HUMAN             Reviewed;        1064 AA.
AC   O75164; Q5VVB1;
DE   RecName: Full=Lysine-specific demethylase 4A;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 3A;
DE   AltName: Full=Jumonji domain-containing protein 2A;
GN   Name=KDM4A; Synonyms=JHDM3A, JMJD2, JMJD2A, KIAA0677;
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0016577; P:histone demethylation; IDA:UniProtKB.
DR   GO; GO:0070544; P:histone H3-K36 demethylation; IDA:GOC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KDM4B_HUMAN             Reviewed;        1096 AA.
AC   O94953; B9EGN8; D6W631; O75274; Q6P3R5; Q9P1V1; Q9UF40;
DE   RecName: Full=Lysine-specific demethylase 4B;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 3B;
DE   AltName: Full=Jumonji domain-containing protein 2B;
GN   Name=KDM4B; Synonyms=JHDM3B, JMJD2B, KIAA0876;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM4C_HUMAN             Reviewed;        1056 AA.
AC   Q9H3R0; B4E1Y4; B7ZL46; F5H347; F5H7P0; O94877; Q2M3M0; Q5JUC9;
AC   Q5VYJ2; Q5VYJ3;
DE   RecName: Full=Lysine-specific demethylase 4C;
DE            EC=1.14.11.-;
DE   AltName: Full=Gene amplified in squamous cell carcinoma 1 protein;
DE            Short=GASC-1 protein;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 3C;
DE   AltName: Full=Jumonji domain-containing protein 2C;
GN   Name=KDM4C; Synonyms=GASC1, JHDM3C, JMJD2C, KIAA0780;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM4D_HUMAN             Reviewed;         523 AA.
AC   Q6B0I6; B3KPC4; Q0VF39; Q9NT41; Q9NW76;
DE   RecName: Full=Lysine-specific demethylase 4D;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 3D;
DE   AltName: Full=Jumonji domain-containing protein 2D;
GN   Name=KDM4D; Synonyms=JHDM3D, JMJD2D;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM4E_HUMAN             Reviewed;         506 AA.
AC   B2RXH2;
DE   RecName: Full=Lysine-specific demethylase 4E;
DE            EC=1.14.11.-;
DE   AltName: Full=KDM4D-like protein;
DE   AltName: Full=Lysine-specific demethylase 4D-like;
GN   Name=KDM4E; Synonyms=KDM4DL;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM5A_HUMAN             Reviewed;        1690 AA.
AC   P29375; A8MV76; Q4LE72; Q86XZ1;
DE   RecName: Full=Lysine-specific demethylase 5A;
DE            EC=1.14.11.-;
DE   AltName: Full=Histone demethylase JARID1A;
DE   AltName: Full=Jumonji/ARID domain-containing protein 1A;
DE   AltName: Full=Retinoblastoma-binding protein 2;
DE            Short=RBBP-2;
GN   Name=KDM5A; Synonyms=JARID1A, RBBP2, RBP2;
DR   GuidetoPHARMACOLOGY; 2680; -.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:GDB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   KDM5B_HUMAN             Reviewed;        1544 AA.
AC   Q9UGL1; O95811; Q15752; Q9Y3Q5;
DE   RecName: Full=Lysine-specific demethylase 5B;
DE            EC=1.14.11.-;
DE   AltName: Full=Cancer/testis antigen 31;
DE            Short=CT31;
DE   AltName: Full=Histone demethylase JARID1B;
DE   AltName: Full=Jumonji/ARID domain-containing protein 1B;
DE   AltName: Full=PLU-1;
DE   AltName: Full=Retinoblastoma-binding protein 2 homolog 1;
DE            Short=RBP2-H1;
GN   Name=KDM5B; Synonyms=JARID1B, PLU1, RBBP2H1;
DR   GuidetoPHARMACOLOGY; 2681; -.
DR   GO; GO:0003677; F:DNA binding; IDA:GDB.
DR   GO; GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:UniProtKB.
DR   GO; GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034720; P:histone H3-K4 demethylation; IDA:UniProtKB.
DR   GO; GO:0034721; P:histone H3-K4 demethylation, trimethyl-H3-K4-specific; IDA:GOC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:GDB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM5C_HUMAN             Reviewed;        1560 AA.
AC   P41229; B0QZ44; B4E3I2; F5H3T1; Q5JUX3; Q5JUX4; Q5JUX5; Q7Z5S5;
DE   RecName: Full=Lysine-specific demethylase 5C;
DE            EC=1.14.11.-;
DE   AltName: Full=Histone demethylase JARID1C;
DE   AltName: Full=Jumonji/ARID domain-containing protein 1C;
DE   AltName: Full=Protein SmcX;
DE   AltName: Full=Protein Xe169;
GN   Name=KDM5C; Synonyms=DXS1272E, JARID1C, SMCX, XE169;
DR   GuidetoPHARMACOLOGY; 2682; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034720; P:histone H3-K4 demethylation; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM8_HUMAN              Reviewed;         416 AA.
AC   Q8N371; B4DLU9; Q6VAK5; Q9H8B1;
DE   RecName: Full=Lysine-specific demethylase 8;
DE            EC=1.14.11.27;
DE   AltName: Full=JmjC domain-containing protein 5;
DE   AltName: Full=Jumonji domain-containing protein 5;
GN   Name=KDM8; Synonyms=JMJD5;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0070544; P:histone H3-K36 demethylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDM5D_HUMAN             Reviewed;        1539 AA.
AC   Q9BY66; A2RU19; A6H8V7; B7ZLX1; Q92509; Q92809; Q9HCU1;
DE   RecName: Full=Lysine-specific demethylase 5D;
DE            EC=1.14.11.-;
DE   AltName: Full=Histocompatibility Y antigen;
DE            Short=H-Y;
DE   AltName: Full=Histone demethylase JARID1D;
DE   AltName: Full=Jumonji/ARID domain-containing protein 1D;
DE   AltName: Full=Protein SmcY;
GN   Name=KDM5D; Synonyms=HY, HYA, JARID1D, KIAA0234, SMCY;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0032453; F:histone demethylase activity (H3-K4 specific); IDA:MGI.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034720; P:histone H3-K4 demethylation; IDA:MGI.
//
ID   KDM6B_HUMAN             Reviewed;        1643 AA.
AC   O15054; C9IZ40; Q96G33;
DE   RecName: Full=Lysine-specific demethylase 6B;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing protein 3;
DE   AltName: Full=Jumonji domain-containing protein 3;
DE   AltName: Full=Lysine demethylase 6B;
GN   Name=KDM6B; Synonyms=JMJD3, KIAA0346;
DR   GuidetoPHARMACOLOGY; 2685; -.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071558; F:histone demethylase activity (H3-K27 specific); EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0071557; P:histone H3-K27 demethylation; EXP:GOC.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   KDM6A_HUMAN             Reviewed;        1401 AA.
AC   O15550; Q52LL9; Q5JVQ7;
DE   RecName: Full=Lysine-specific demethylase 6A;
DE            EC=1.14.11.-;
DE   AltName: Full=Histone demethylase UTX;
DE   AltName: Full=Ubiquitously-transcribed TPR protein on the X chromosome;
DE   AltName: Full=Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein;
GN   Name=KDM6A; Synonyms=UTX;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071558; F:histone demethylase activity (H3-K27 specific); IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048333; P:mesodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0048570; P:notochord morphogenesis; IEA:Ensembl.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
//
ID   KDM7A_HUMAN             Reviewed;         941 AA.
AC   Q6ZMT4; A4D1S9; C9JJH9; C9JQU2; Q6MZL8; Q9C0E5;
DE   RecName: Full=Lysine-specific demethylase 7A;
DE            EC=1.14.11.-;
DE   AltName: Full=JmjC domain-containing histone demethylation protein 1D;
DE   AltName: Full=Lysine-specific demethylase 7;
GN   Name=KDM7A; Synonyms=JHDM1D, KDM7, KIAA1718;
DR   GuidetoPHARMACOLOGY; 2686; -.
DR   GO; GO:0071558; F:histone demethylase activity (H3-K27 specific); IDA:UniProtKB.
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.
DR   GO; GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0035575; F:histone demethylase activity (H4-K20 specific); IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0071557; P:histone H3-K27 demethylation; IDA:UniProtKB.
DR   GO; GO:0070544; P:histone H3-K36 demethylation; IDA:UniProtKB.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IDA:UniProtKB.
DR   GO; GO:0035574; P:histone H4-K20 demethylation; IDA:UniProtKB.
DR   GO; GO:0030901; P:midbrain development; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KDSR_HUMAN              Reviewed;         332 AA.
AC   Q06136; B2R5Y1;
DE   RecName: Full=3-ketodihydrosphingosine reductase;
DE            Short=KDS reductase;
DE            EC=1.1.1.102;
DE   AltName: Full=3-dehydrosphinganine reductase;
DE   AltName: Full=Follicular variant translocation protein 1;
DE            Short=FVT-1;
DE   Flags: Precursor;
GN   Name=KDSR; Synonyms=FVT1;
DR   GO; GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.
DR   GO; GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   KEAP1_HUMAN             Reviewed;         624 AA.
AC   Q14145; B3KPD5; Q6LEP0; Q8WTX1; Q9BPY9;
DE   RecName: Full=Kelch-like ECH-associated protein 1;
DE   AltName: Full=Cytosolic inhibitor of Nrf2;
DE            Short=INrf2;
DE   AltName: Full=Kelch-like protein 19;
GN   Name=KEAP1; Synonyms=INRF2, KIAA0132, KLHL19;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0045604; P:regulation of epidermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KELL_HUMAN              Reviewed;         732 AA.
AC   P23276; B2RBV4; Q96RS8; Q99885;
DE   RecName: Full=Kell blood group glycoprotein;
DE            EC=3.4.24.-;
DE   AltName: CD_antigen=CD238;
GN   Name=KEL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042310; P:vasoconstriction; TAS:HGNC.
//
ID   KERA_HUMAN              Reviewed;         352 AA.
AC   O60938;
DE   RecName: Full=Keratocan;
DE            Short=KTN;
DE   AltName: Full=Keratan sulfate proteoglycan keratocan;
DE   Flags: Precursor;
GN   Name=KERA; Synonyms=SLRR2B;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0061303; P:cornea development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   KFA_HUMAN               Reviewed;         303 AA.
AC   Q63HM1; A2RUB3;
DE   RecName: Full=Kynurenine formamidase;
DE            Short=KFA;
DE            Short=KFase;
DE            EC=3.5.1.9;
DE   AltName: Full=Arylformamidase;
DE   AltName: Full=N-formylkynurenine formamidase;
DE            Short=FKF;
GN   Name=AFMID;
DR   GO; GO:0004061; F:arylformamidase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034354; P:'de novo' NAD biosynthetic process from tryptophan; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:UniProtKB-UniPathway.
//
ID   KGFL1_HUMAN             Reviewed;          97 AA.
AC   Q2TVT4;
DE   RecName: Full=Putative keratinocyte growth factor-like protein 1;
DE            Short=KGF-like protein 1;
GN   Name=KGFLP1;
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:InterPro.
//
ID   KGFL2_HUMAN             Reviewed;          97 AA.
AC   Q2TVT3;
DE   RecName: Full=Putative keratinocyte growth factor-like protein 2;
DE            Short=KGF-like protein 2;
GN   Name=KGFLP2;
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:InterPro.
//
ID   KGP1_HUMAN              Reviewed;         671 AA.
AC   Q13976; E2PU10; P14619; Q5JSJ6; Q6P5T7;
DE   RecName: Full=cGMP-dependent protein kinase 1;
DE            Short=cGK 1;
DE            Short=cGK1;
DE            EC=2.7.11.12;
DE   AltName: Full=cGMP-dependent protein kinase I;
DE            Short=cGKI;
GN   Name=PRKG1; Synonyms=PRKG1B, PRKGR1A, PRKGR1B;
DR   GuidetoPHARMACOLOGY; 1492; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005246; F:calcium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0090331; P:negative regulation of platelet aggregation; IMP:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0043087; P:regulation of GTPase activity; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KGP2_HUMAN              Reviewed;         762 AA.
AC   Q13237; O00125; O60916;
DE   RecName: Full=cGMP-dependent protein kinase 2;
DE            Short=cGK 2;
DE            Short=cGK2;
DE            EC=2.7.11.12;
DE   AltName: Full=cGMP-dependent protein kinase II;
DE            Short=cGKII;
GN   Name=PRKG2; Synonyms=PRKGR2;
DR   GuidetoPHARMACOLOGY; 1493; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004692; F:cGMP-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KGUA_HUMAN              Reviewed;         197 AA.
AC   Q16774; B1ANH1;
DE   RecName: Full=Guanylate kinase;
DE            EC=2.7.4.8;
DE   AltName: Full=GMP kinase;
GN   Name=GUK1; Synonyms=GMK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004385; F:guanylate kinase activity; IDA:UniProtKB.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR   GO; GO:0046060; P:dATP metabolic process; IEA:Ensembl.
DR   GO; GO:0006185; P:dGDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046054; P:dGMP metabolic process; IEA:Ensembl.
DR   GO; GO:0017144; P:drug metabolic process; TAS:Reactome.
DR   GO; GO:0046711; P:GDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0019673; P:GDP-mannose metabolic process; IEA:Ensembl.
DR   GO; GO:0034436; P:glycoprotein transport; IEA:Ensembl.
DR   GO; GO:0046037; P:GMP metabolic process; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006163; P:purine nucleotide metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KHD3L_HUMAN             Reviewed;         217 AA.
AC   Q587J8; B2RNW7;
DE   RecName: Full=KHDC3-like protein;
DE   AltName: Full=ES cell-associated transcript 1 protein;
GN   Name=KHDC3L; Synonyms=C6orf221, ECAT1;
//
ID   KHDC1_HUMAN             Reviewed;         237 AA.
AC   Q4VXA5; Q5JSQ7; Q8WTV2; Q96NQ5;
DE   RecName: Full=KH homology domain-containing protein 1;
GN   Name=KHDC1; Synonyms=C6orf148;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   KHDR1_HUMAN             Reviewed;         443 AA.
AC   Q07666; D3DPP3; Q6PJX7; Q8NB97; Q99760;
DE   RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 1;
DE   AltName: Full=GAP-associated tyrosine phosphoprotein p62;
DE   AltName: Full=Src-associated in mitosis 68 kDa protein;
DE            Short=Sam68;
DE   AltName: Full=p21 Ras GTPase-activating protein-associated p62;
DE   AltName: Full=p68;
GN   Name=KHDRBS1; Synonyms=SAM68;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008143; F:poly(A) binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0046833; P:positive regulation of RNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IPI:GOC.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0046831; P:regulation of RNA export from nucleus; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KHDCL_HUMAN             Reviewed;         128 AA.
AC   Q5JSQ8; E1P535;
DE   RecName: Full=Putative KHDC1-like protein;
GN   Name=KHDC1L;
//
ID   KHDR2_HUMAN             Reviewed;         349 AA.
AC   Q5VWX1; A8K7M8; Q8N4I4; Q8TCZ4;
DE   RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 2;
DE   AltName: Full=Sam68-like mammalian protein 1;
DE            Short=SLM-1;
DE            Short=hSLM-1;
GN   Name=KHDRBS2; Synonyms=SLM1;
DR   GO; GO:0008143; F:poly(A) binding; IEA:Ensembl.
DR   GO; GO:0008266; F:poly(U) RNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KHDR3_HUMAN             Reviewed;         346 AA.
AC   O75525; Q6NUL8; Q9UPA8;
DE   RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3;
DE   AltName: Full=RNA-binding protein T-Star;
DE   AltName: Full=Sam68-like mammalian protein 2;
DE            Short=SLM-2;
DE   AltName: Full=Sam68-like phosphotyrosine protein;
GN   Name=KHDRBS3; Synonyms=SALP, SLM2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KHK_HUMAN               Reviewed;         298 AA.
AC   P50053; Q6IBK2; Q99532; Q9BRJ3; Q9UMN1;
DE   RecName: Full=Ketohexokinase;
DE            EC=2.7.1.3;
DE   AltName: Full=Hepatic fructokinase;
GN   Name=KHK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004454; F:ketohexokinase activity; EXP:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; EXP:GOC.
DR   GO; GO:0006001; P:fructose catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KHNYN_HUMAN             Reviewed;         678 AA.
AC   O15037; Q86TZ6; Q8IUQ2; Q96BA9;
DE   RecName: Full=Protein KHNYN;
DE   AltName: Full=KH and NYN domain-containing protein;
GN   Name=KHNYN; Synonyms=KIAA0323;
//
ID   KI13A_HUMAN             Reviewed;        1805 AA.
AC   Q9H1H9; A0JP21; A0JP22; F2Z382; Q5THQ2; Q5THQ3; Q9H193; Q9H194;
AC   Q9H1H8;
DE   RecName: Full=Kinesin-like protein KIF13A;
DE   AltName: Full=Kinesin-like protein RBKIN;
GN   Name=KIF13A; Synonyms=RBKIN;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035459; P:cargo loading into vesicle; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; IMP:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0072383; P:plus-end-directed vesicle transport along microtubule; ISS:UniProtKB.
//
ID   KI13B_HUMAN             Reviewed;        1826 AA.
AC   Q9NQT8; F8VPJ2; O75134; Q9BYJ6;
DE   RecName: Full=Kinesin-like protein KIF13B;
DE   AltName: Full=Kinesin-like protein GAKIN;
GN   Name=KIF13B; Synonyms=GAKIN, KIAA0639;
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; TAS:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
//
ID   KI16B_HUMAN             Reviewed;        1317 AA.
AC   Q96L93; A6NKJ9; A7E2A8; B1AKG3; B1AKT7; C9JDN5; C9JI52; C9JSM8;
AC   C9JWJ7; Q2TBF5; Q5HYC0; Q5HYK1; Q5JWW3; Q5TFK5; Q86VL9; Q86YS5;
AC   Q8IYU0; Q9BQJ8; Q9BQM0; Q9BQM1; Q9BQM5; Q9H5U0; Q9HCI2; Q9NXN9;
DE   RecName: Full=Kinesin-like protein KIF16B;
DE   AltName: Full=Sorting nexin-23;
GN   Name=KIF16B; Synonyms=C20orf23, KIAA1590, SNX23;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; IDA:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0007492; P:endoderm development; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001704; P:formation of primary germ layer; ISS:UniProtKB.
DR   GO; GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0032801; P:receptor catabolic process; IMP:UniProtKB.
DR   GO; GO:0001919; P:regulation of receptor recycling; IMP:UniProtKB.
//
ID   KI18A_HUMAN             Reviewed;         898 AA.
AC   Q8NI77; Q4VPE3; Q86VS5; Q9H0F3;
DE   RecName: Full=Kinesin-like protein KIF18A;
DE   AltName: Full=Marrow stromal KIF18A;
DE            Short=MS-KIF18A;
GN   Name=KIF18A; ORFNames=OK/SW-cl.108;
DR   GO; GO:0003779; F:actin binding; IPI:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070463; F:tubulin-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0007019; P:microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   KI18B_HUMAN             Reviewed;         864 AA.
AC   Q86Y91; A6NJI2; B7ZM49; B9EGM8; D5L6I1;
DE   RecName: Full=Kinesin-like protein KIF18B;
GN   Name=KIF18B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProt.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0007019; P:microtubule depolymerization; IDA:UniProt.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0051302; P:regulation of cell division; IDA:UniProtKB.
//
ID   KI20A_HUMAN             Reviewed;         890 AA.
AC   O95235; D3DQB6;
DE   RecName: Full=Kinesin-like protein KIF20A;
DE   AltName: Full=GG10_2;
DE   AltName: Full=Mitotic kinesin-like protein 2;
DE            Short=MKlp2;
DE   AltName: Full=Rab6-interacting kinesin-like protein;
DE   AltName: Full=Rabkinesin-6;
GN   Name=KIF20A; Synonyms=MKLP2, RAB6KIFL;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   KI20B_HUMAN             Reviewed;        1820 AA.
AC   Q96Q89; A8MXM7; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8;
AC   Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9;
AC   Q86X82; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5;
DE   RecName: Full=Kinesin-like protein KIF20B;
DE   AltName: Full=Cancer/testis antigen 90;
DE            Short=CT90;
DE   AltName: Full=Kinesin-related motor interacting with PIN1;
DE   AltName: Full=M-phase phosphoprotein 1;
DE            Short=MPP1;
GN   Name=KIF20B; Synonyms=KRMP1, MPHOSPH1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007050; P:cell cycle arrest; NAS:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000087; P:mitotic M phase; TAS:ProtInc.
DR   GO; GO:0007088; P:regulation of mitosis; NAS:UniProtKB.
//
ID   KI21A_HUMAN             Reviewed;        1674 AA.
AC   Q7Z4S6; A8MX28; B0I1R9; B9EGE4; F5H0C3; F5H219; Q2UVF1; Q6UKL9;
AC   Q7Z668; Q86WZ5; Q8IVZ8; Q9C0F5; Q9NXU4; Q9Y590;
DE   RecName: Full=Kinesin-like protein KIF21A;
DE   AltName: Full=Kinesin-like protein KIF2;
DE   AltName: Full=Renal carcinoma antigen NY-REN-62;
GN   Name=KIF21A; Synonyms=KIAA1708, KIF2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   KI21B_HUMAN             Reviewed;        1637 AA.
AC   O75037; B2RP62; B7ZMI0; Q5T4J3;
DE   RecName: Full=Kinesin-like protein KIF21B;
GN   Name=KIF21B; Synonyms=KIAA0449;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   KI26A_HUMAN             Reviewed;        1882 AA.
AC   Q9ULI4; Q8TAZ7; Q96GK3; Q9UFL3;
DE   RecName: Full=Kinesin-like protein KIF26A;
GN   Name=KIF26A; Synonyms=KIAA1236;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048484; P:enteric nervous system development; ISS:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0009968; P:negative regulation of signal transduction; ISS:UniProtKB.
DR   GO; GO:0001560; P:regulation of cell growth by extracellular stimulus; ISS:UniProtKB.
//
ID   KI26B_HUMAN             Reviewed;        2108 AA.
AC   Q2KJY2; Q6ZQR9; Q6ZUZ0; Q8IUN3; Q8IVR1; Q9NWB4;
DE   RecName: Full=Kinesin-like protein KIF26B;
GN   Name=KIF26B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0072092; P:ureteric bud invasion; IEA:Ensembl.
//
ID   KI2L1_HUMAN             Reviewed;         348 AA.
AC   P43626; O43470; Q32WE6;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DL1;
DE   AltName: Full=CD158 antigen-like family member A;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 1;
DE            Short=NKAT-1;
DE   AltName: Full=p58 natural killer cell receptor clones CL-42/47.11;
DE            Short=p58 NK receptor CL-42/47.11;
DE   AltName: Full=p58.1 MHC class-I-specific NK receptor;
DE   AltName: CD_antigen=CD158a;
DE   Flags: Precursor;
GN   Name=KIR2DL1; Synonyms=CD158A, NKAT1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002769; P:natural killer cell inhibitory signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KI2L2_HUMAN             Reviewed;         348 AA.
AC   P43627; C6EVR8; Q14951;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DL2;
DE   AltName: Full=CD158 antigen-like family member B1;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 6;
DE            Short=NKAT-6;
DE   AltName: Full=p58 natural killer cell receptor clone CL-43;
DE            Short=p58 NK receptor CL-43;
DE   AltName: CD_antigen=CD158b1;
DE   Flags: Precursor;
GN   Name=KIR2DL2; Synonyms=CD158B1, NKAT6;
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KI2L3_HUMAN             Reviewed;         341 AA.
AC   P43628; O43472; P78402; Q14944; Q14945; Q9UM51; Q9UQ70;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DL3;
DE   AltName: Full=CD158 antigen-like family member B2;
DE   AltName: Full=KIR-023GB;
DE   AltName: Full=Killer inhibitory receptor cl 2-3;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=NKAT2a;
DE   AltName: Full=NKAT2b;
DE   AltName: Full=Natural killer-associated transcript 2;
DE            Short=NKAT-2;
DE   AltName: Full=p58 natural killer cell receptor clone CL-6;
DE            Short=p58 NK receptor CL-6;
DE   AltName: Full=p58.2 MHC class-I-specific NK receptor;
DE   AltName: CD_antigen=CD158b2;
DE   Flags: Precursor;
GN   Name=KIR2DL3; Synonyms=CD158B2, KIRCL23, NKAT2;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KI2L4_HUMAN             Reviewed;         377 AA.
AC   Q99706; A8W795; O14621; O14622; O14623; O14624; O43534; P78400;
AC   P78401; Q8N738; Q99559; Q99560; Q99561; Q99562; Q9UQJ7;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DL4;
DE   AltName: Full=CD158 antigen-like family member D;
DE   AltName: Full=G9P;
DE   AltName: Full=Killer cell inhibitory receptor 103AS;
DE            Short=KIR-103AS;
DE   AltName: Full=MHC class I NK cell receptor KIR103AS;
DE   AltName: CD_antigen=CD158d;
DE   Flags: Precursor;
GN   Name=KIR2DL4; Synonyms=CD158D, KIR103AS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KI2LA_HUMAN             Reviewed;         375 AA.
AC   Q8N109;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DL5A;
DE   AltName: CD_antigen=CD158f1;
DE   Flags: Precursor;
GN   Name=KIR2DL5A; Synonyms=CD158F, CD158F1, KIR2DL5;
//
ID   KI2LB_HUMAN             Reviewed;         375 AA.
AC   Q8NHK3;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DL5B;
DE   AltName: Full=CD158 antigen-like family member F2;
DE   AltName: Full=Killer cell immunoglobulin-like receptor 2DLX;
DE   AltName: CD_antigen=CD158f2;
DE   Flags: Precursor;
GN   Name=KIR2DL5B; Synonyms=CD158F, CD158F2, KIR2DL5, KIR2DLX;
//
ID   KI2S1_HUMAN             Reviewed;         304 AA.
AC   Q14954; O43471;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DS1;
DE   AltName: Full=CD158 antigen-like family member H;
DE   AltName: Full=MHC class I NK cell receptor Eb6 ActI;
DE   AltName: CD_antigen=CD158h;
DE   Flags: Precursor;
GN   Name=KIR2DS1; Synonyms=CD158H;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   KI2S2_HUMAN             Reviewed;         304 AA.
AC   P43631; Q14955; Q6H2G9;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DS2;
DE   AltName: Full=CD158 antigen-like family member J;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=NK receptor 183 ActI;
DE   AltName: Full=Natural killer-associated transcript 5;
DE            Short=NKAT-5;
DE   AltName: Full=p58 natural killer cell receptor clone CL-49;
DE            Short=p58 NK receptor CL-49;
DE   AltName: CD_antigen=CD158j;
DE   Flags: Precursor;
GN   Name=KIR2DS2; Synonyms=CD158J, NKAT5;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   KI2S3_HUMAN             Reviewed;         304 AA.
AC   Q14952; O00644;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DS3;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 7;
DE            Short=NKAT-7;
DE   Flags: Precursor;
GN   Name=KIR2DS3; Synonyms=NKAT7;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   KI2S4_HUMAN             Reviewed;         304 AA.
AC   P43632; Q6H2G7;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DS4;
DE   AltName: Full=CD158 antigen-like family member I;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 8;
DE            Short=NKAT-8;
DE   AltName: Full=P58 natural killer cell receptor clones CL-39/CL-17;
DE            Short=p58 NK receptor CL-39/CL-17;
DE   AltName: CD_antigen=CD158i;
DE   Flags: Precursor;
GN   Name=KIR2DS4; Synonyms=CD158I, KKA3, NKAT8;
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   KI2S5_HUMAN             Reviewed;         304 AA.
AC   Q14953;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 2DS5;
DE   AltName: Full=CD158 antigen-like family member G;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 9;
DE            Short=NKAT-9;
DE   AltName: CD_antigen=CD158g;
DE   Flags: Precursor;
GN   Name=KIR2DS5; Synonyms=CD158G, NKAT9;
DR   GO; GO:0030110; F:HLA-C specific inhibitory MHC class I receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   KI3L1_HUMAN             Reviewed;         444 AA.
AC   P43629; O43473; Q14946; Q16541;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 3DL1;
DE   AltName: Full=CD158 antigen-like family member E;
DE   AltName: Full=HLA-BW4-specific inhibitory NK cell receptor;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 3;
DE            Short=NKAT-3;
DE   AltName: Full=p70 natural killer cell receptor clones CL-2/CL-11;
DE            Short=p70 NK receptor CL-2/CL-11;
DE   AltName: CD_antigen=CD158e;
DE   Flags: Precursor;
GN   Name=KIR3DL1; Synonyms=CD158E, NKAT3, NKB1;
DR   GO; GO:0030109; F:HLA-B specific inhibitory MHC class I receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   KI3L2_HUMAN             Reviewed;         455 AA.
AC   P43630; Q13238; Q14947; Q14948; Q92684; Q95366; Q95367; Q95368;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 3DL2;
DE   AltName: Full=CD158 antigen-like family member K;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 4;
DE            Short=NKAT-4;
DE   AltName: Full=p70 natural killer cell receptor clone CL-5;
DE            Short=p70 NK receptor CL-5;
DE   AltName: CD_antigen=CD158k;
DE   Flags: Precursor;
GN   Name=KIR3DL2; Synonyms=CD158K, NKAT4;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KI3P1_HUMAN             Reviewed;         328 AA.
AC   A8MWS1;
DE   RecName: Full=Putative killer cell immunoglobulin-like receptor like protein KIR3DP1;
DE   AltName: CD_antigen=CD158c;
DE   Flags: Precursor;
GN   Name=KIR3DP1; Synonyms=CD158C, KIR2DS6, KIR48, KIRX;
//
ID   KI3S1_HUMAN             Reviewed;         387 AA.
AC   Q14943;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 3DS1;
DE   AltName: Full=MHC class I NK cell receptor;
DE   AltName: Full=Natural killer-associated transcript 10;
DE            Short=NKAT-10;
DE   Flags: Precursor;
GN   Name=KIR3DS1; Synonyms=NKAT10;
DR   GO; GO:0032393; F:MHC class I receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   KI3L3_HUMAN             Reviewed;         410 AA.
AC   Q8N743; A9PL62; A9PL64; A9PL65; A9PL66; A9PL67; A9PL68; A9PZV4;
AC   A9PZV7; A9PZV8; A9Q066; A9Q0R5; A9Q242; A9Q250; A9Q251; O95056;
AC   Q1X775; Q1X777; Q1X778; Q1X779; Q1X780; Q1X781; Q1X782; Q1X783;
AC   Q7Z7N4; Q8NHI2; Q8NHI3; Q9UEI4;
DE   RecName: Full=Killer cell immunoglobulin-like receptor 3DL3;
DE   AltName: Full=CD158 antigen-like family member Z;
DE   AltName: Full=Killer cell inhibitory receptor 1;
DE   AltName: CD_antigen=CD158z;
DE   Flags: Precursor;
GN   Name=KIR3DL3; Synonyms=CD158Z, KIR3DL7, KIRC1;
//
ID   KI3X1_HUMAN             Reviewed;         352 AA.
AC   Q9H7L2; B7WNL0; Q8N0S4;
DE   RecName: Full=Putative killer cell immunoglobulin-like receptor-like protein KIR3DX1;
DE   AltName: Full=Leukocyte receptor cluster member 12;
DE   Flags: Precursor;
GN   Name=KIR3DX1; Synonyms=KIR3DL0, LENG12;
//
ID   KI67_HUMAN              Reviewed;        3256 AA.
AC   P46013; Q5VWH2;
DE   RecName: Full=Antigen KI-67;
GN   Name=MKI67;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006259; P:DNA metabolic process; IEA:Ensembl.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
//
ID   KIAS3_HUMAN             Reviewed;         241 AA.
AC   Q8N7Y1; Q14CX1;
DE   RecName: Full=Putative uncharacterized protein KIRREL3-AS3;
DE   AltName: Full=KIRREL3 antisense RNA 1;
DE   AltName: Full=KIRREL3 antisense gene protein 1;
DE   AltName: Full=Proline-rich protein 10;
GN   Name=KIRREL3-AS3; Synonyms=NCRNA00288, PRR10;
//
ID   KIAS1_HUMAN             Reviewed;         181 AA.
AC   Q9Y6Z4; Q2M1U8; Q5SZV0; Q5SZV1; Q9Y6Z3;
DE   RecName: Full=Putative uncharacterized protein KIF25-AS1;
DE   AltName: Full=KIF25 antisense RNA 1;
DE   AltName: Full=KIF25 antisense gene protein 1;
DE   AltName: Full=Protein HGC6.1;
GN   Name=KIF25-AS1; Synonyms=C6orf54, NCRNA00300;
//
ID   KIBRA_HUMAN             Reviewed;        1113 AA.
AC   Q8IX03; B4DK05; O94946; Q6MZX4; Q6Y2F8; Q7Z4G8; Q8WVM4; Q9BT29;
DE   RecName: Full=Protein KIBRA;
DE   AltName: Full=HBeAg-binding protein 3;
DE   AltName: Full=Kidney and brain protein;
DE            Short=KIBRA;
DE   AltName: Full=WW domain-containing protein 1;
GN   Name=WWC1; Synonyms=KIAA0869;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0035330; P:regulation of hippo signaling; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KIF11_HUMAN             Reviewed;        1056 AA.
AC   P52732; A0AV49; B2RMV3; Q15716; Q5VWX0;
DE   RecName: Full=Kinesin-like protein KIF11;
DE   AltName: Full=Kinesin-like protein 1;
DE   AltName: Full=Kinesin-like spindle protein HKSP;
DE   AltName: Full=Kinesin-related motor protein Eg5;
DE   AltName: Full=Thyroid receptor-interacting protein 5;
DE            Short=TR-interacting protein 5;
DE            Short=TRIP-5;
GN   Name=KIF11; Synonyms=EG5, KNSL1, TRIP5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0007100; P:mitotic centrosome separation; IEA:Ensembl.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:ProtInc.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IDA:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   KIF12_HUMAN             Reviewed;         646 AA.
AC   Q96FN5; Q5TBE0;
DE   RecName: Full=Kinesin-like protein KIF12;
GN   Name=KIF12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   KIF15_HUMAN             Reviewed;        1388 AA.
AC   Q9NS87; Q17RV9; Q69YL6; Q96JX7; Q9H280;
DE   RecName: Full=Kinesin-like protein KIF15;
DE   AltName: Full=Kinesin-like protein 2;
DE            Short=hKLP2;
DE   AltName: Full=Kinesin-like protein 7;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-62;
GN   Name=KIF15; Synonyms=KLP2, KNSL7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
//
ID   KIF14_HUMAN             Reviewed;        1648 AA.
AC   Q15058; Q14CI8; Q4G0A5; Q5T1W3;
DE   RecName: Full=Kinesin-like protein KIF14;
GN   Name=KIF14; Synonyms=KIAA0042;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IDA:MGI.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0033624; P:negative regulation of integrin activation; IMP:MGI.
DR   GO; GO:0030155; P:regulation of cell adhesion; IMP:MGI.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:MGI.
DR   GO; GO:0032487; P:regulation of Rap protein signal transduction; IMP:MGI.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:MGI.
//
ID   KIF17_HUMAN             Reviewed;        1029 AA.
AC   Q9P2E2; A2A3Q7; A2A3Q8; O95077; Q53YS6; Q5VWA9; Q6GSA8; Q8N411;
DE   RecName: Full=Kinesin-like protein KIF17;
DE   AltName: Full=KIF3-related motor protein;
GN   Name=KIF17; Synonyms=KIAA1405, KIF3X;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:Ensembl.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0031503; P:protein complex localization; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:Ensembl.
//
ID   KIF19_HUMAN             Reviewed;         998 AA.
AC   Q2TAC6; A6NLG2; B7ZKR1; Q52M87; Q8N1X8; Q8TAB6;
DE   RecName: Full=Kinesin-like protein KIF19;
GN   Name=KIF19;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; ISS:UniProtKB.
DR   GO; GO:0060404; P:axonemal microtubule depolymerization; ISS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0070462; P:plus-end specific microtubule depolymerization; ISS:UniProtKB.
//
ID   KIF1A_HUMAN             Reviewed;        1690 AA.
AC   Q12756; B0I1S5; F5H045; O95068; Q13355; Q14752; Q2NKJ6; Q4LE42;
AC   Q53T78; Q59GH1; Q63Z40; Q6P1R9; Q7KZ57;
DE   RecName: Full=Kinesin-like protein KIF1A;
DE   AltName: Full=Axonal transporter of synaptic vesicles;
DE   AltName: Full=Microtubule-based motor KIF1A;
DE   AltName: Full=Unc-104- and KIF1A-related protein;
DE            Short=hUnc-104;
GN   Name=KIF1A; Synonyms=ATSV, C2orf20;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0008089; P:anterograde axon cargo transport; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
//
ID   KIF1B_HUMAN             Reviewed;        1816 AA.
AC   O60333; A6NFS8; A6NKQ4; Q4VXC3; Q4VXC4; Q4VXC5; Q4VXC6; Q96Q94;
AC   Q9BV80; Q9P280;
DE   RecName: Full=Kinesin-like protein KIF1B;
DE            Short=Klp;
GN   Name=KIF1B; Synonyms=KIAA0591, KIAA1448;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; TAS:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; ISS:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; ISS:UniProtKB.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; ISS:UniProtKB.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; ISS:UniProtKB.
//
ID   KIF1C_HUMAN             Reviewed;        1103 AA.
AC   O43896; D3DTL6; O75186; Q5U618;
DE   RecName: Full=Kinesin-like protein KIF1C;
GN   Name=KIF1C; Synonyms=KIAA0706;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:ProtInc.
//
ID   KIF22_HUMAN             Reviewed;         665 AA.
AC   Q14807; B2R5M0; B7Z265; O60845; O94814; Q53F58; Q9BT46;
DE   RecName: Full=Kinesin-like protein KIF22;
DE   AltName: Full=Kinesin-like DNA-binding protein;
DE   AltName: Full=Kinesin-like protein 4;
GN   Name=KIF22; Synonyms=KID, KNSL4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
//
ID   KIF23_HUMAN             Reviewed;         960 AA.
AC   Q02241; Q8WVP0;
DE   RecName: Full=Kinesin-like protein KIF23;
DE   AltName: Full=Kinesin-like protein 5;
DE   AltName: Full=Mitotic kinesin-like protein 1;
GN   Name=KIF23; Synonyms=KNSL5, MKLP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000022; P:mitotic spindle elongation; TAS:ProtInc.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0051256; P:spindle midzone assembly involved in mitosis; IMP:UniProtKB.
//
ID   KIF24_HUMAN             Reviewed;        1368 AA.
AC   Q5T7B8; Q2TB93; Q5T7B5; Q5T7B7; Q6ZU97; Q6ZUZ2; Q86XZ0; Q9NV43;
DE   RecName: Full=Kinesin-like protein KIF24;
GN   Name=KIF24; Synonyms=C9orf48;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0007019; P:microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   KIF25_HUMAN             Reviewed;         384 AA.
AC   Q9UIL4; O94775; Q5SZU9;
DE   RecName: Full=Kinesin-like protein KIF25;
DE   AltName: Full=Kinesin-like protein 3;
GN   Name=KIF25; Synonyms=KNSL3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; TAS:ProtInc.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:BHF-UCL.
DR   GO; GO:0006996; P:organelle organization; TAS:ProtInc.
//
ID   KIF27_HUMAN             Reviewed;        1401 AA.
AC   Q86VH2; B2RTR8; Q5T6W0; Q86VH0; Q86VH1; Q9UF54;
DE   RecName: Full=Kinesin-like protein KIF27;
GN   Name=KIF27;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
//
ID   KIF28_HUMAN             Reviewed;         967 AA.
AC   B7ZC32;
DE   RecName: Full=Kinesin-like protein KIF28P;
DE   AltName: Full=Kinesin-like protein 6;
GN   Name=KIF28P; Synonyms=KLP6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0072384; P:organelle transport along microtubule; ISS:UniProtKB.
//
ID   KIF2A_HUMAN             Reviewed;         706 AA.
AC   O00139; A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; Q7Z5I3; Q8N5Q7;
DE   RecName: Full=Kinesin-like protein KIF2A;
DE   AltName: Full=Kinesin-2;
DE            Short=hK2;
GN   Name=KIF2A; Synonyms=KIF2, KNS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   KIF2B_HUMAN             Reviewed;         673 AA.
AC   Q8N4N8; Q96MA2; Q9BXG6;
DE   RecName: Full=Kinesin-like protein KIF2B;
GN   Name=KIF2B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007019; P:microtubule depolymerization; IMP:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051983; P:regulation of chromosome segregation; IMP:UniProtKB.
//
ID   KIF2C_HUMAN             Reviewed;         725 AA.
AC   Q99661; B3ITR9; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q9BWV8;
DE   RecName: Full=Kinesin-like protein KIF2C;
DE   AltName: Full=Kinesin-like protein 6;
DE   AltName: Full=Mitotic centromere-associated kinesin;
DE            Short=MCAK;
GN   Name=KIF2C; Synonyms=KNSL6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019237; F:centromeric DNA binding; TAS:ProtInc.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IMP:HGNC.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007019; P:microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051983; P:regulation of chromosome segregation; IMP:UniProtKB.
//
ID   KIF3B_HUMAN             Reviewed;         747 AA.
AC   O15066; B2RMP4; E1P5M5;
DE   RecName: Full=Kinesin-like protein KIF3B;
DE   AltName: Full=HH0048;
DE   AltName: Full=Microtubule plus end-directed kinesin motor 3B;
DE   Contains:
DE     RecName: Full=Kinesin-like protein KIF3B, N-terminally processed;
GN   Name=KIF3B; Synonyms=KIAA0359;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0008089; P:anterograde axon cargo transport; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007368; P:determination of left/right symmetry; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007100; P:mitotic centrosome separation; TAS:BHF-UCL.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.
DR   GO; GO:0072383; P:plus-end-directed vesicle transport along microtubule; TAS:BHF-UCL.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IMP:BHF-UCL.
//
ID   KIF3A_HUMAN             Reviewed;         699 AA.
AC   Q9Y496; A8MSW9; Q59EN1; Q86XE9; Q9Y6V4;
DE   RecName: Full=Kinesin-like protein KIF3A;
DE   AltName: Full=Microtubule plus end-directed kinesin motor 3A;
GN   Name=KIF3A; Synonyms=KIF3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008574; F:plus-end-directed microtubule motor activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0006996; P:organelle organization; TAS:ProtInc.
DR   GO; GO:0072383; P:plus-end-directed vesicle transport along microtubule; TAS:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   KIF3C_HUMAN             Reviewed;         793 AA.
AC   O14782; O43544; Q4ZG18; Q53SX5; Q562F7;
DE   RecName: Full=Kinesin-like protein KIF3C;
GN   Name=KIF3C;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
//
ID   KIF4A_HUMAN             Reviewed;        1232 AA.
AC   O95239; B2R7V5; D3DVU4; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3;
DE   RecName: Full=Chromosome-associated kinesin KIF4A;
DE   AltName: Full=Chromokinesin-A;
GN   Name=KIF4A; Synonyms=KIF4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0008089; P:anterograde axon cargo transport; TAS:ProtInc.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0006996; P:organelle organization; TAS:ProtInc.
//
ID   KIF4B_HUMAN             Reviewed;        1234 AA.
AC   Q2VIQ3;
DE   RecName: Full=Chromosome-associated kinesin KIF4B;
DE   AltName: Full=Chromokinesin-B;
GN   Name=KIF4B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
//
ID   KIF5A_HUMAN             Reviewed;        1032 AA.
AC   Q12840; A6H8M5; Q4LE26;
DE   RecName: Full=Kinesin heavy chain isoform 5A;
DE   AltName: Full=Kinesin heavy chain neuron-specific 1;
DE   AltName: Full=Neuronal kinesin heavy chain;
DE            Short=NKHC;
GN   Name=KIF5A; Synonyms=NKHC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   KIF5C_HUMAN             Reviewed;         957 AA.
AC   O60282; O95079; Q2YDC5;
DE   RecName: Full=Kinesin heavy chain isoform 5C;
DE   AltName: Full=Kinesin heavy chain neuron-specific 2;
GN   Name=KIF5C; Synonyms=KIAA0531, NKHC2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0051028; P:mRNA transport; ISS:UniProtKB.
DR   GO; GO:0006996; P:organelle organization; TAS:ProtInc.
//
ID   KIF6_HUMAN              Reviewed;         814 AA.
AC   Q6ZMV9; Q2MDE3; Q2MDE4; Q5T8J6; Q6ZWE3; Q86T87; Q8WTV4;
DE   RecName: Full=Kinesin-like protein KIF6;
GN   Name=KIF6; Synonyms=C6orf102;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   KIF7_HUMAN              Reviewed;        1343 AA.
AC   Q2M1P5; Q3SXY0; Q6UXE9; Q8IW72;
DE   RecName: Full=Kinesin-like protein KIF7;
GN   Name=KIF7; ORFNames=UNQ340/PRO539;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.
//
ID   KIF9_HUMAN              Reviewed;         790 AA.
AC   Q9HAQ2; Q86Z28; Q9H8A4;
DE   RecName: Full=Kinesin-like protein KIF9;
GN   Name=KIF9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
//
ID   KIFA3_HUMAN             Reviewed;         792 AA.
AC   Q92845; B1AKU4; B1AKU5; B2RDL1; B7Z8A3; F5H591; Q8NHU7; Q9H416;
DE   RecName: Full=Kinesin-associated protein 3;
DE            Short=KAP-3;
DE            Short=KAP3;
DE   AltName: Full=Smg GDS-associated protein;
GN   Name=KIFAP3; Synonyms=KIF3AP, SMAP;
DR   GO; GO:0019894; F:kinesin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0072383; P:plus-end-directed vesicle transport along microtubule; TAS:BHF-UCL.
DR   GO; GO:0046587; P:positive regulation of calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KIFC1_HUMAN             Reviewed;         673 AA.
AC   Q9BW19; O60887; Q14834; Q4KMP0; Q5SU09; Q6GMS7; Q6P4A5; Q9UQP7;
DE   RecName: Full=Kinesin-like protein KIFC1;
DE   AltName: Full=Kinesin-like protein 2;
DE   AltName: Full=Kinesin-related protein HSET;
GN   Name=KIFC1; Synonyms=HSET, KNSL2;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; NAS:UniProtKB.
//
ID   KIFC3_HUMAN             Reviewed;         833 AA.
AC   Q9BVG8; A8K6S2; O75299; Q49A29; Q49AQ0; Q59G19; Q8IUT3; Q96HW6;
DE   RecName: Full=Kinesin-like protein KIFC3;
GN   Name=KIFC3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; TAS:ProtInc.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
DR   GO; GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB.
//
ID   KIFC2_HUMAN             Reviewed;         838 AA.
AC   Q96AC6;
DE   RecName: Full=Kinesin-like protein KIFC2;
GN   Name=KIFC2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
//
ID   KILIN_HUMAN             Reviewed;         178 AA.
AC   B2CW77;
DE   RecName: Full=Killin;
GN   Name=KLLN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   KIME_HUMAN              Reviewed;         396 AA.
AC   Q03426;
DE   RecName: Full=Mevalonate kinase;
DE            Short=MK;
DE            EC=2.7.1.36;
GN   Name=MVK;
DR   GuidetoPHARMACOLOGY; 640; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004496; F:mevalonate kinase activity; IDA:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019287; P:isopentenyl diphosphate biosynthetic process, mevalonate pathway; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KIN17_HUMAN             Reviewed;         393 AA.
AC   O60870;
DE   RecName: Full=DNA/RNA-binding protein KIN17;
DE   AltName: Full=Binding to curved DNA;
DE   AltName: Full=KIN, antigenic determinant of recA protein homolog;
GN   Name=KIN; Synonyms=BTCD, KIN17;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KINH_HUMAN              Reviewed;         963 AA.
AC   P33176; A0AVB2; Q5VZ85;
DE   RecName: Full=Kinesin-1 heavy chain;
DE   AltName: Full=Conventional kinesin heavy chain;
DE   AltName: Full=Ubiquitous kinesin heavy chain;
DE            Short=UKHC;
GN   Name=KIF5B; Synonyms=KNS, KNS1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; ISS:HGNC.
DR   GO; GO:0003777; F:microtubule motor activity; ISS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007028; P:cytoplasm organization; IEA:Ensembl.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:ProtInc.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IDA:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0035617; P:stress granule disassembly; ISS:BHF-UCL.
DR   GO; GO:0047496; P:vesicle transport along microtubule; ISS:HGNC.
//
ID   KIRR1_HUMAN             Reviewed;         757 AA.
AC   Q96J84; Q5W0F8; Q5XKC6; Q7Z696; Q7Z7N8; Q8TB15; Q9H9N1; Q9NVA5;
DE   RecName: Full=Kin of IRRE-like protein 1;
DE   AltName: Full=Kin of irregular chiasm-like protein 1;
DE   AltName: Full=Nephrin-like protein 1;
DE   Flags: Precursor;
GN   Name=KIRREL; Synonyms=KIRREL1, NEPH1;
DR   GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
//
ID   KIRR2_HUMAN             Reviewed;         708 AA.
AC   Q6UWL6; C9JHF1; C9JJ76; F1T0I2; Q6P1R1; Q7Z5P1; Q7Z5P2; Q96IQ8;
AC   Q9H0T1;
DE   RecName: Full=Kin of IRRE-like protein 2;
DE   AltName: Full=Kin of irregular chiasm-like protein 2;
DE   AltName: Full=Nephrin-like protein 3;
DE   Flags: Precursor;
GN   Name=KIRREL2; Synonyms=NEPH3; ORFNames=UNQ5827/PRO19646;
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
//
ID   KIRR3_HUMAN             Reviewed;         778 AA.
AC   Q8IZU9; Q3MIJ7; Q6UWJ9; Q6UWL5; Q96JG0;
DE   RecName: Full=Kin of IRRE-like protein 3;
DE   AltName: Full=Kin of irregular chiasm-like protein 3;
DE   AltName: Full=Nephrin-like protein 2;
DE   Flags: Precursor;
GN   Name=KIRREL3; Synonyms=KIAA1867, NEPH2;
GN   ORFNames=UNQ5923/PRO4502/PRO19814;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0021740; P:principal sensory nucleus of trigeminal nerve development; IEA:Ensembl.
//
ID   KISHA_HUMAN             Reviewed;          72 AA.
AC   Q8TBQ9; Q0P692;
DE   RecName: Full=Protein kish-A;
DE   AltName: Full=Transmembrane protein 167;
DE   AltName: Full=Transmembrane protein 167A;
DE   Flags: Precursor;
GN   Name=TMEM167A; Synonyms=TMEM167;
//
ID   KISHB_HUMAN             Reviewed;          74 AA.
AC   Q9NRX6; B2RUU9;
DE   RecName: Full=Protein kish-B;
DE   AltName: Full=Transmembrane protein 167B;
DE   Flags: Precursor;
GN   Name=TMEM167B; Synonyms=C1orf119; ORFNames=AD-020;
//
ID   KISS1_HUMAN             Reviewed;         138 AA.
AC   Q15726; A8K6N0; Q9HBP1;
DE   RecName: Full=Metastasis-suppressor KiSS-1;
DE   AltName: Full=Kisspeptin-1;
DE   Contains:
DE     RecName: Full=Metastin;
DE     AltName: Full=Kisspeptin-54;
DE   Contains:
DE     RecName: Full=Kisspeptin-14;
DE   Contains:
DE     RecName: Full=Kisspeptin-13;
DE   Contains:
DE     RecName: Full=Kisspeptin-10;
DE   Flags: Precursor;
GN   Name=KISS1; ORFNames=PP5098;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0060112; P:generation of ovulation cycle rhythm; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0033686; P:positive regulation of luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
//
ID   KISSR_HUMAN             Reviewed;         398 AA.
AC   Q969F8; A5D8U2; B2RTV1; Q96QG0;
DE   RecName: Full=KiSS-1 receptor;
DE            Short=KiSS-1R;
DE   AltName: Full=G-protein coupled receptor 54;
DE   AltName: Full=G-protein coupled receptor OT7T175;
DE            Short=hOT7T175;
DE   AltName: Full=Hypogonadotropin-1;
DE   AltName: Full=Kisspeptins receptor;
DE   AltName: Full=Metastin receptor;
GN   Name=KISS1R; Synonyms=AXOR12, GPR54;
DR   GuidetoPHARMACOLOGY; 266; -.
DR   GO; GO:0042923; F:neuropeptide binding; IEA:Ensembl.
DR   GO; GO:0008188; F:neuropeptide receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:GOC.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
//
ID   KITH_HUMAN              Reviewed;         234 AA.
AC   P04183; B2RC58; Q969V0; Q9UMG9;
DE   RecName: Full=Thymidine kinase, cytosolic;
DE            EC=2.7.1.21;
GN   Name=TK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
DR   GO; GO:0004797; F:thymidine kinase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009157; P:deoxyribonucleoside monophosphate biosynthetic process; TAS:GOC.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0060138; P:fetal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; EXP:GOC.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0051414; P:response to cortisol; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0014856; P:skeletal muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046104; P:thymidine metabolic process; IEA:Ensembl.
//
ID   KITM_HUMAN              Reviewed;         265 AA.
AC   O00142; B4DGJ7; B4DZK7; B7ZAB1; E9PH08; O15238;
DE   RecName: Full=Thymidine kinase 2, mitochondrial;
DE            EC=2.7.1.21;
DE   AltName: Full=Mt-TK;
DE   Flags: Precursor;
GN   Name=TK2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004137; F:deoxycytidine kinase activity; IEA:Ensembl.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0004797; F:thymidine kinase activity; IEA:Ensembl.
DR   GO; GO:0046092; P:deoxycytidine metabolic process; IEA:Ensembl.
DR   GO; GO:0009157; P:deoxyribonucleoside monophosphate biosynthetic process; TAS:GOC.
DR   GO; GO:0009262; P:deoxyribonucleotide metabolic process; IEA:Ensembl.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046104; P:thymidine metabolic process; IEA:Ensembl.
//
ID   KIT_HUMAN               Reviewed;         976 AA.
AC   P10721; B5A956; D5LXN2; D5M931; F5H8F8; Q6IQ28; Q99662; Q9UM99;
DE   RecName: Full=Mast/stem cell growth factor receptor Kit;
DE            Short=SCFR;
DE            EC=2.7.10.1;
DE   AltName: Full=Piebald trait protein;
DE            Short=PBT;
DE   AltName: Full=Proto-oncogene c-Kit;
DE   AltName: Full=Tyrosine-protein kinase Kit;
DE   AltName: Full=p145 c-kit;
DE   AltName: Full=v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog;
DE   AltName: CD_antigen=CD117;
DE   Flags: Precursor;
GN   Name=KIT; Synonyms=SCFR;
DR   GuidetoPHARMACOLOGY; 1805; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019955; F:cytokine binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0005020; F:stem cell factor receptor activity; IEA:Ensembl.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0002371; P:dendritic cell cytokine production; ISS:UniProtKB.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; ISS:UniProtKB.
DR   GO; GO:0048565; P:digestive tract development; ISS:UniProtKB.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0038162; P:erythropoietin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038093; P:Fc receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; TAS:UniProtKB.
DR   GO; GO:0002327; P:immature B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0038109; P:Kit signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0002551; P:mast cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0032762; P:mast cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0043303; P:mast cell degranulation; IMP:UniProtKB.
DR   GO; GO:0060374; P:mast cell differentiation; ISS:UniProtKB.
DR   GO; GO:0070662; P:mast cell proliferation; TAS:UniProtKB.
DR   GO; GO:0035855; P:megakaryocyte development; ISS:UniProtKB.
DR   GO; GO:0097326; P:melanocyte adhesion; ISS:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0097324; P:melanocyte migration; ISS:UniProtKB.
DR   GO; GO:0002318; P:myeloid progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0043473; P:pigmentation; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:UniProtKB.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; TAS:UniProtKB.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; TAS:UniProtKB.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:UniProtKB.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0048070; P:regulation of developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; TAS:GOC.
DR   GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; TAS:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   KIZ_HUMAN               Reviewed;         673 AA.
AC   Q2M2Z5; B4DDE9; B4DK54; Q4G0M8; Q4G0S5; Q5BKY3; Q6P0M6; Q71ME0;
AC   Q9NZ35;
DE   RecName: Full=Centrosomal protein kizuna;
DE   AltName: Full=Polo-like kinase 1 substrate 1;
GN   Name=KIZ; Synonyms=C20orf19, NCRNA00153, PLK1S1; ORFNames=HT013;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   KKCC1_HUMAN             Reviewed;         505 AA.
AC   Q8N5S9; Q9BQH3;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase kinase 1;
DE            Short=CaM-KK 1;
DE            Short=CaM-kinase kinase 1;
DE            Short=CaMKK 1;
DE            EC=2.7.11.17;
DE   AltName: Full=CaM-kinase IV kinase;
DE   AltName: Full=Calcium/calmodulin-dependent protein kinase kinase alpha;
DE            Short=CaM-KK alpha;
DE            Short=CaM-kinase kinase alpha;
DE            Short=CaMKK alpha;
GN   Name=CAMKK1; Synonyms=CAMKKA;
DR   GuidetoPHARMACOLOGY; 1956; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KKCC2_HUMAN             Reviewed;         588 AA.
AC   Q96RR4; A8K7Q7; O94883; Q8IUG2; Q8IUG3; Q8N3I4; Q8WY03; Q8WY04;
AC   Q8WY05; Q8WY06; Q96RP1; Q96RP2; Q96RR3; Q9BWE9; Q9UER3; Q9UES2;
AC   Q9Y5N2;
DE   RecName: Full=Calcium/calmodulin-dependent protein kinase kinase 2;
DE            Short=CaM-KK 2;
DE            Short=CaM-kinase kinase 2;
DE            Short=CaMKK 2;
DE            EC=2.7.11.17;
DE   AltName: Full=Calcium/calmodulin-dependent protein kinase kinase beta;
DE            Short=CaM-KK beta;
DE            Short=CaM-kinase kinase beta;
DE            Short=CaMKK beta;
GN   Name=CAMKK2; Synonyms=CAMKKB, KIAA0787;
DR   GuidetoPHARMACOLOGY; 1957; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; TAS:UniProtKB.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; TAS:UniProtKB.
//
ID   KKLC1_HUMAN             Reviewed;         113 AA.
AC   Q5H943;
DE   RecName: Full=Kita-kyushu lung cancer antigen 1;
DE            Short=KK-LC-1;
DE   AltName: Full=Cancer/testis antigen 83;
GN   Name=CT83; Synonyms=CXorf61, KKLC1;
//
ID   KLC1_HUMAN              Reviewed;         573 AA.
AC   Q07866; A6NF62; F8VTM4; Q7RTM2; Q7RTM3; Q7RTM5; Q7RTP9; Q7RTQ3;
AC   Q7RTQ5; Q7RTQ6; Q86SF5; Q86TF5; Q86V74; Q86V75; Q86V76; Q86V77;
AC   Q86V78; Q86V79; Q96H62;
DE   RecName: Full=Kinesin light chain 1;
DE            Short=KLC 1;
GN   Name=KLC1; Synonyms=KLC, KNS2;
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0035617; P:stress granule disassembly; ISS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KLAS1_HUMAN             Reviewed;          82 AA.
AC   Q8NEE0;
DE   RecName: Full=Putative uncharacterized protein KLHL30-AS1;
DE   AltName: Full=KLHL30 antisense RNA 1;
GN   Name=KLHL30-AS1; Synonyms=C2orf19;
//
ID   KLC2_HUMAN              Reviewed;         622 AA.
AC   Q9H0B6; A8MXL7; B2RDY4; Q9H9C8; Q9HA20;
DE   RecName: Full=Kinesin light chain 2;
DE            Short=KLC 2;
GN   Name=KLC2;
DR   GO; GO:0019894; F:kinesin binding; ISS:BHF-UCL.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
//
ID   KLC3_HUMAN              Reviewed;         504 AA.
AC   Q6P597; A0AVM3; A2RUT6; Q6GMU2; Q8NAL1; Q8WWJ9;
DE   RecName: Full=Kinesin light chain 3;
DE   AltName: Full=KLC2-like;
DE   AltName: Full=kinesin light chain 2;
GN   Name=KLC3; Synonyms=KLC2, KLC2L;
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Ensembl.
//
ID   KLC4_HUMAN              Reviewed;         619 AA.
AC   Q9NSK0; B3KNY4; B3KPI3; B3KSQ3; Q66K28; Q96EG6;
DE   RecName: Full=Kinesin light chain 4;
DE            Short=KLC 4;
DE   AltName: Full=Kinesin-like protein 8;
GN   Name=KLC4; Synonyms=KNSL8;
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
//
ID   KLD10_HUMAN             Reviewed;         442 AA.
AC   Q6PID8; Q86Y99; Q92554;
DE   RecName: Full=Kelch domain-containing protein 10;
GN   Name=KLHDC10; Synonyms=KIAA0265;
//
ID   KLD7A_HUMAN             Reviewed;         777 AA.
AC   Q5VTJ3; Q8N8W6;
DE   RecName: Full=Kelch domain-containing protein 7A;
GN   Name=KLHDC7A;
//
ID   KLD7B_HUMAN             Reviewed;         594 AA.
AC   Q96G42;
DE   RecName: Full=Kelch domain-containing protein 7B;
GN   Name=KLHDC7B;
//
ID   KLD8A_HUMAN             Reviewed;         350 AA.
AC   Q8IYD2; B3KU70; Q9NVG5;
DE   RecName: Full=Kelch domain-containing protein 8A;
DE   AltName: Full=Substitute for delta-EGFR expression 1;
DE            Short=S-delta-E1;
GN   Name=KLHDC8A;
//
ID   KLD8B_HUMAN             Reviewed;         354 AA.
AC   Q8IXV7;
DE   RecName: Full=Kelch domain-containing protein 8B;
GN   Name=KLHDC8B; ORFNames=FP17659;
//
ID   KLDC1_HUMAN             Reviewed;         406 AA.
AC   Q8N7A1; B3KXD9; Q8WYI1;
DE   RecName: Full=Kelch domain-containing protein 1;
GN   Name=KLHDC1; ORFNames=MSTP025;
//
ID   KLDC2_HUMAN             Reviewed;         406 AA.
AC   Q9Y2U9; B3KPF9; Q6IAF0; Q86TY9;
DE   RecName: Full=Kelch domain-containing protein 2;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 33;
DE   AltName: Full=Host cell factor homolog LCP;
DE   AltName: Full=Host cell factor-like protein 1;
DE            Short=HCLP-1;
GN   Name=KLHDC2; Synonyms=HCA33;
//
ID   KLDC4_HUMAN             Reviewed;         520 AA.
AC   Q8TBB5; D3DUN3; D3DUN4; D3DUN5; Q96F29; Q9BVN3;
DE   RecName: Full=Kelch domain-containing protein 4;
GN   Name=KLHDC4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   KLDC9_HUMAN             Reviewed;         349 AA.
AC   Q8NEP7; Q5SY56; Q6NXT9; Q6PKN4; Q8N5E1; Q8NA16;
DE   RecName: Full=Kelch domain-containing protein 9;
DE   AltName: Full=Kelch/ankyrin repeat-containing cyclin A1-interacting protein;
GN   Name=KLHDC9; Synonyms=KARCA1;
//
ID   KLDC3_HUMAN             Reviewed;         382 AA.
AC   Q9BQ90; A8K2W9;
DE   RecName: Full=Kelch domain-containing protein 3;
DE   AltName: Full=Protein Peas;
DE   AltName: Full=Testis intracellular mediator protein;
GN   Name=KLHDC3; Synonyms=PEAS;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; NAS:UniProtKB.
//
ID   KLF10_HUMAN             Reviewed;         480 AA.
AC   Q13118; A8MVH0; B2R794; L0R4P6; L0R679; O75411; Q503B2;
DE   RecName: Full=Krueppel-like factor 10;
DE   AltName: Full=EGR-alpha;
DE   AltName: Full=Transforming growth factor-beta-inducible early growth response protein 1;
DE            Short=TGFB-inducible early growth response protein 1;
DE            Short=TIEG-1;
GN   Name=KLF10; Synonyms=TIEG, TIEG1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   KLF11_HUMAN             Reviewed;         512 AA.
AC   O14901; B4DZE7; Q9EPF4;
DE   RecName: Full=Krueppel-like factor 11;
DE   AltName: Full=Transforming growth factor-beta-inducible early growth response protein 2;
DE            Short=TGFB-inducible early growth response protein 2;
DE            Short=TIEG-2;
GN   Name=KLF11; Synonyms=FKLF, TIEG2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   KLF12_HUMAN             Reviewed;         402 AA.
AC   Q9Y4X4; A8K5T2; L0R3J4; Q5VZM7; Q9UHZ0;
DE   RecName: Full=Krueppel-like factor 12;
DE   AltName: Full=Transcriptional repressor AP-2rep;
GN   Name=KLF12; Synonyms=AP2REP; ORFNames=HSPC122;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001227; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   KLF13_HUMAN             Reviewed;         288 AA.
AC   Q9Y2Y9; Q9Y356;
DE   RecName: Full=Krueppel-like factor 13;
DE   AltName: Full=Basic transcription element-binding protein 3;
DE            Short=BTE-binding protein 3;
DE   AltName: Full=Novel Sp1-like zinc finger transcription factor 1;
DE   AltName: Full=RANTES factor of late activated T-lymphocytes 1;
DE            Short=RFLAT-1;
DE   AltName: Full=Transcription factor BTEB3;
DE   AltName: Full=Transcription factor NSLP1;
GN   Name=KLF13; Synonyms=BTEB3, NSLP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   KLF14_HUMAN             Reviewed;         323 AA.
AC   Q8TD94; Q19A42; Q19A43;
DE   RecName: Full=Krueppel-like factor 14;
DE   AltName: Full=Basic transcription element-binding protein 5;
DE            Short=BTE-binding protein 5;
DE   AltName: Full=Transcription factor BTEB5;
GN   Name=KLF14; Synonyms=BTEB5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF15_HUMAN             Reviewed;         416 AA.
AC   Q9UIH9;
DE   RecName: Full=Krueppel-like factor 15;
DE   AltName: Full=Kidney-enriched krueppel-like factor;
GN   Name=KLF15; Synonyms=KKLF;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IC:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:2000757; P:negative regulation of peptidyl-lysine acetylation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
//
ID   KLF16_HUMAN             Reviewed;         252 AA.
AC   Q9BXK1;
DE   RecName: Full=Krueppel-like factor 16;
DE   AltName: Full=Basic transcription element-binding protein 4;
DE            Short=BTE-binding protein 4;
DE   AltName: Full=Novel Sp1-like zinc finger transcription factor 2;
DE   AltName: Full=Transcription factor BTEB4;
DE   AltName: Full=Transcription factor NSLP2;
GN   Name=KLF16; Synonyms=BTEB4, NSLP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF17_HUMAN             Reviewed;         389 AA.
AC   Q5JT82; Q86VQ7; Q8N805;
DE   RecName: Full=Krueppel-like factor 17;
DE   AltName: Full=Zinc finger protein 393;
GN   Name=KLF17; Synonyms=ZNF393;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF1_HUMAN              Reviewed;         362 AA.
AC   Q13351; Q6PIJ5; Q92899;
DE   RecName: Full=Krueppel-like factor 1;
DE   AltName: Full=Erythroid krueppel-like transcription factor;
DE            Short=EKLF;
GN   Name=KLF1; Synonyms=EKLF;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF2_HUMAN              Reviewed;         355 AA.
AC   Q9Y5W3; Q6IPC4; Q9UJS5; Q9UKR6;
DE   RecName: Full=Krueppel-like factor 2;
DE   AltName: Full=Lung krueppel-like factor;
GN   Name=KLF2; Synonyms=LKLF;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0071409; P:cellular response to cycloheximide; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0071499; P:cellular response to laminar fluid shear stress; IMP:BHF-UCL.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.
DR   GO; GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060509; P:Type I pneumocyte differentiation; IEA:Ensembl.
//
ID   KLF3_HUMAN              Reviewed;         345 AA.
AC   P57682; Q6PIR1; Q86TN0; Q9P2X6;
DE   RecName: Full=Krueppel-like factor 3;
DE   AltName: Full=Basic krueppel-like factor;
DE   AltName: Full=CACCC-box-binding protein BKLF;
DE   AltName: Full=TEF-2;
GN   Name=KLF3; Synonyms=BKLF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF5_HUMAN              Reviewed;         457 AA.
AC   Q13887; L0R3U5; L0R4T9; Q9UHP8;
DE   RecName: Full=Krueppel-like factor 5;
DE   AltName: Full=Basic transcription element-binding protein 2;
DE            Short=BTE-binding protein 2;
DE   AltName: Full=Colon krueppel-like factor;
DE   AltName: Full=GC-box-binding protein 2;
DE   AltName: Full=Intestinal-enriched krueppel-like factor;
DE   AltName: Full=Transcription factor BTEB2;
GN   Name=KLF5; Synonyms=BTEB2, CKLF, IKLF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0030033; P:microvillus assembly; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   KLF4_HUMAN              Reviewed;         513 AA.
AC   O43474; B2R8S4; B3KT79; L0R3I6; L0R4N5; P78338; Q5T3J8; Q5T3J9;
AC   Q8N717; Q9UNP3;
DE   RecName: Full=Krueppel-like factor 4;
DE   AltName: Full=Epithelial zinc finger protein EZF;
DE   AltName: Full=Gut-enriched krueppel-like factor;
GN   Name=KLF4; Synonyms=EZF, GKLF;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0071409; P:cellular response to cycloheximide; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:1901653; P:cellular response to peptide; IEA:Ensembl.
DR   GO; GO:0009913; P:epidermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0048730; P:epidermis morphogenesis; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0014740; P:negative regulation of muscle hyperplasia; IEA:Ensembl.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0046985; P:positive regulation of hemoglobin biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0031077; P:post-embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0035166; P:post-embryonic hemopoiesis; IMP:BHF-UCL.
DR   GO; GO:0045595; P:regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   KLF6_HUMAN              Reviewed;         283 AA.
AC   Q99612; B2RE86; B4DDN0; D3DRR1; F5H3M5; Q5VUT7; Q5VUT8; Q9BT79;
DE   RecName: Full=Krueppel-like factor 6;
DE   AltName: Full=B-cell-derived protein 1;
DE   AltName: Full=Core promoter element-binding protein;
DE   AltName: Full=GC-rich sites-binding factor GBF;
DE   AltName: Full=Proto-oncogene BCD1;
DE   AltName: Full=Suppressor of tumorigenicity 12 protein;
DE   AltName: Full=Transcription factor Zf9;
GN   Name=KLF6; Synonyms=BCD1, COPEB, CPBP, ST12;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030183; P:B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF7_HUMAN              Reviewed;         302 AA.
AC   O75840; B2RB03; B7Z4F7; C9JF04; E7EWH1; L0R4P2; Q7Z3H8; Q96E51;
DE   RecName: Full=Krueppel-like factor 7;
DE   AltName: Full=Ubiquitous krueppel-like factor;
GN   Name=KLF7; Synonyms=UKLF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF8_HUMAN              Reviewed;         359 AA.
AC   O95600; B4DJN3; E7EQQ8; L0R3U8; L0R4U2; Q2M246; Q59GV5; Q5HYQ5;
AC   Q5JXP7; Q6MZJ7; Q9UGC4;
DE   RecName: Full=Krueppel-like factor 8;
DE   AltName: Full=Basic krueppel-like factor 3;
DE   AltName: Full=Zinc finger protein 741;
GN   Name=KLF8; Synonyms=BKLF3, ZNF741;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLF9_HUMAN              Reviewed;         244 AA.
AC   Q13886; B2R943; Q16196;
DE   RecName: Full=Krueppel-like factor 9;
DE   AltName: Full=Basic transcription element-binding protein 1;
DE            Short=BTE-binding protein 1;
DE   AltName: Full=GC-box-binding protein 1;
DE   AltName: Full=Transcription factor BTEB1;
GN   Name=KLF9; Synonyms=BTEB, BTEB1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0050847; P:progesterone receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLH10_HUMAN             Reviewed;         608 AA.
AC   Q6JEL2; Q6NW28; Q96MC0;
DE   RecName: Full=Kelch-like protein 10;
GN   Name=KLHL10;
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0048808; P:male genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   KLH11_HUMAN             Reviewed;         708 AA.
AC   Q9NVR0;
DE   RecName: Full=Kelch-like protein 11;
DE   Flags: Precursor;
GN   Name=KLHL11;
//
ID   KLH12_HUMAN             Reviewed;         568 AA.
AC   Q53G59; A6NEN8; B7Z7B8; Q9HBX5;
DE   RecName: Full=Kelch-like protein 12;
DE   AltName: Full=CUL3-interacting protein 1;
DE   AltName: Full=DKIR homolog;
DE            Short=hDKIR;
GN   Name=KLHL12; Synonyms=C3IP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048208; P:COPII vesicle coating; IMP:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:UniProtKB.
//
ID   KLH13_HUMAN             Reviewed;         655 AA.
AC   Q9P2N7; B3KV78; B3KWM7; B7Z3S9; B7Z5P2; B7Z802; D3DWH6; Q6P2E3;
AC   Q96QI7; Q9UDN9;
DE   RecName: Full=Kelch-like protein 13;
DE   AltName: Full=BTB and kelch domain-containing protein 2;
GN   Name=KLHL13; Synonyms=BKLHD2, KIAA1309;
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   KLH14_HUMAN             Reviewed;         628 AA.
AC   Q9P2G3; A6NNW1; B4DHA0; Q8WU41;
DE   RecName: Full=Kelch-like protein 14;
DE   AltName: Full=Protein interactor of Torsin-1A;
DE            Short=Printor;
DE            Short=Protein interactor of torsinA;
GN   Name=KLHL14; Synonyms=KIAA1384;
//
ID   KLH15_HUMAN             Reviewed;         604 AA.
AC   Q96M94; Q32MN3; Q8NDA3; Q96BM6; Q9C0I6;
DE   RecName: Full=Kelch-like protein 15;
GN   Name=KLHL15; Synonyms=KIAA1677;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   KLH17_HUMAN             Reviewed;         642 AA.
AC   Q6TDP4; Q5SV94;
DE   RecName: Full=Kelch-like protein 17;
DE   AltName: Full=Actinfilin;
GN   Name=KLHL17;
DR   GO; GO:0032947; F:protein complex scaffold; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   KLH18_HUMAN             Reviewed;         574 AA.
AC   O94889; A8K612; Q7Z3E8; Q8N125;
DE   RecName: Full=Kelch-like protein 18;
GN   Name=KLHL18; Synonyms=KIAA0795; ORFNames=OK/SW-cl.74;
//
ID   KLH20_HUMAN             Reviewed;         609 AA.
AC   Q9Y2M5; B3KMA0; Q5TZF2; Q5ZF45; Q9H457;
DE   RecName: Full=Kelch-like protein 20;
DE   AltName: Full=Kelch-like ECT2-interacting protein;
DE   AltName: Full=Kelch-like protein X;
GN   Name=KLHL20; Synonyms=KLEIP;
DR   GO; GO:0019964; F:interferon-gamma binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; TAS:UniProtKB.
//
ID   KLH21_HUMAN             Reviewed;         597 AA.
AC   Q9UJP4; B3KQP2; O75057; Q5SY26; Q5SY28; Q8N4I6; Q8NF10;
DE   RecName: Full=Kelch-like protein 21;
GN   Name=KLHL21; Synonyms=KIAA0469;
DR   GO; GO:0035853; P:chromosome passenger complex localization to spindle midzone; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
//
ID   KLH22_HUMAN             Reviewed;         634 AA.
AC   Q53GT1; A8K3Q4; A8MTV3; D3DX30; Q96B68; Q96KC6;
DE   RecName: Full=Kelch-like protein 22;
GN   Name=KLHL22;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
//
ID   KLH23_HUMAN             Reviewed;         558 AA.
AC   Q8NBE8; Q8N9B9; Q96FT8;
DE   RecName: Full=Kelch-like protein 23;
GN   Name=KLHL23;
//
ID   KLH24_HUMAN             Reviewed;         600 AA.
AC   Q6TFL4; A5PLN8; Q9H620; Q9NXT9;
DE   RecName: Full=Kelch-like protein 24;
DE   AltName: Full=Kainate receptor-interacting protein for GluR6;
DE            Short=KRIP6;
DE   AltName: Full=Protein DRE1;
GN   Name=KLHL24; Synonyms=DRE1;
//
ID   KLH25_HUMAN             Reviewed;         589 AA.
AC   Q9H0H3; B2RDH2; B3KRT7;
DE   RecName: Full=Kelch-like protein 25;
DE   AltName: Full=Ectoderm-neural cortex protein 2;
DE            Short=ENC-2;
GN   Name=KLHL25; Synonyms=ENC2;
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.
//
ID   KLH26_HUMAN             Reviewed;         615 AA.
AC   Q53HC5; Q8TAP0; Q9NUX3;
DE   RecName: Full=Kelch-like protein 26;
GN   Name=KLHL26;
//
ID   KLH28_HUMAN             Reviewed;         571 AA.
AC   Q9NXS3; Q0VAL5;
DE   RecName: Full=Kelch-like protein 28;
DE   AltName: Full=BTB/POZ domain-containing protein 5;
GN   Name=KLHL28; Synonyms=BTBD5;
//
ID   KLH29_HUMAN             Reviewed;         875 AA.
AC   Q96CT2; Q8N388; Q96BF0; Q96PW7;
DE   RecName: Full=Kelch-like protein 29;
DE   AltName: Full=Kelch repeat and BTB domain-containing protein 9;
GN   Name=KLHL29; Synonyms=KBTBD9, KIAA1921;
//
ID   KLH30_HUMAN             Reviewed;         578 AA.
AC   Q0D2K2; Q6ZUS1;
DE   RecName: Full=Kelch-like protein 30;
GN   Name=KLHL30;
//
ID   KLH31_HUMAN             Reviewed;         634 AA.
AC   Q9H511; A6N9J2; B2RP49;
DE   RecName: Full=Kelch-like protein 31;
DE   AltName: Full=BTB and kelch domain-containing protein 6;
DE   AltName: Full=Kelch repeat and BTB domain-containing protein 1;
DE   AltName: Full=Kelch-like protein KLHL;
GN   Name=KLHL31; Synonyms=BKLHD6, KBTBD1, KLHL;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KLH33_HUMAN             Reviewed;         533 AA.
AC   A6NCF5;
DE   RecName: Full=Kelch-like protein 33;
GN   Name=KLHL33;
//
ID   KLH34_HUMAN             Reviewed;         644 AA.
AC   Q8N239;
DE   RecName: Full=Kelch-like protein 34;
GN   Name=KLHL34;
//
ID   KLH32_HUMAN             Reviewed;         620 AA.
AC   Q96NJ5; B7Z346; B7Z4E2; E1P528; Q5THT0; Q96PY7;
DE   RecName: Full=Kelch-like protein 32;
DE   AltName: Full=BTB and kelch domain-containing protein 5;
GN   Name=KLHL32; Synonyms=BKLHD5, KIAA1900;
//
ID   KLH36_HUMAN             Reviewed;         616 AA.
AC   Q8N4N3; Q8N5G6; Q9H9U6;
DE   RecName: Full=Kelch-like protein 36;
GN   Name=KLHL36; Synonyms=C16orf44;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   KLH35_HUMAN             Reviewed;         363 AA.
AC   Q6PF15; A2RU06; Q86XM7; Q8NBB1;
DE   RecName: Full=Kelch-like protein 35;
GN   Name=KLHL35;
//
ID   KLH38_HUMAN             Reviewed;         581 AA.
AC   Q2WGJ6; A0PK12;
DE   RecName: Full=Kelch-like protein 38;
GN   Name=KLHL38; Synonyms=C8orfK36;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   KLH40_HUMAN             Reviewed;         621 AA.
AC   Q2TBA0; Q86SI1; Q96MR2;
DE   RecName: Full=Kelch-like protein 40;
DE   AltName: Full=Kelch repeat and BTB domain-containing protein 5;
DE   AltName: Full=Sarcosynapsin;
GN   Name=KLHL40; Synonyms=KBTBD5, SRYP;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   KLH41_HUMAN             Reviewed;         606 AA.
AC   O60662; Q53R42;
DE   RecName: Full=Kelch-like protein 41;
DE   AltName: Full=Kel-like protein 23;
DE   AltName: Full=Kelch repeat and BTB domain-containing protein 10;
DE   AltName: Full=Kelch-related protein 1;
DE   AltName: Full=Sarcosin;
GN   Name=KLHL41; Synonyms=KBTBD10, KRP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030239; P:myofibril assembly; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0031275; P:regulation of lateral pseudopodium assembly; IEA:Ensembl.
DR   GO; GO:0045661; P:regulation of myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:2000291; P:regulation of myoblast proliferation; ISS:UniProtKB.
DR   GO; GO:2001014; P:regulation of skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006941; P:striated muscle contraction; TAS:ProtInc.
//
ID   KLH42_HUMAN             Reviewed;         505 AA.
AC   Q9P2K6; Q2VPK1; Q8N334;
DE   RecName: Full=Kelch-like protein 42;
DE   AltName: Full=Cullin-3-binding protein 9;
DE            Short=Ctb9;
DE   AltName: Full=Kelch domain-containing protein 5;
GN   Name=KLHL42; Synonyms=KIAA1340, KLHDC5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
//
ID   KLHL1_HUMAN             Reviewed;         748 AA.
AC   Q9NR64; A8K5X0; Q5VZ64; Q9H4X4; Q9NR65; Q9P238;
DE   RecName: Full=Kelch-like protein 1;
GN   Name=KLHL1; Synonyms=KIAA1490;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
//
ID   KLHL2_HUMAN             Reviewed;         593 AA.
AC   O95198; A6NCM7; B4DFH7; F5H6M3; Q8N484; Q8TBH5;
DE   RecName: Full=Kelch-like protein 2;
DE   AltName: Full=Actin-binding protein Mayven;
GN   Name=KLHL2;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   KLHL3_HUMAN             Reviewed;         587 AA.
AC   Q9UH77; B2RBK7; Q9UH75; Q9UH76; Q9ULU0; Q9Y6V6;
DE   RecName: Full=Kelch-like protein 3;
GN   Name=KLHL3; Synonyms=KIAA1129;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0072156; P:distal tubule morphogenesis; IMP:UniProtKB.
DR   GO; GO:0050801; P:ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0070294; P:renal sodium ion absorption; IMP:UniProtKB.
//
ID   KLHL5_HUMAN             Reviewed;         755 AA.
AC   Q96PQ7; A8K170; B7WP68; E9PCF4; F8WAE7; G3XA92; Q6Y881; Q86XW0;
AC   Q9NUK3; Q9NV27; Q9NVA9; Q9Y2X2;
DE   RecName: Full=Kelch-like protein 5;
GN   Name=KLHL5;
//
ID   KLHL6_HUMAN             Reviewed;         621 AA.
AC   Q8WZ60; B2RB31; D3DNS8; Q8N5I1; Q8N892;
DE   RecName: Full=Kelch-like protein 6;
GN   Name=KLHL6;
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0002467; P:germinal center formation; IEA:Ensembl.
//
ID   KLHL7_HUMAN             Reviewed;         586 AA.
AC   Q8IXQ5; A4D144; B7Z5I9; G5E9G3; Q7Z765; Q96MV2; Q9BQF8; Q9UDQ9;
DE   RecName: Full=Kelch-like protein 7;
GN   Name=KLHL7;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   KLHL4_HUMAN             Reviewed;         718 AA.
AC   Q9C0H6; B2RTW2; Q9Y3J5;
DE   RecName: Full=Kelch-like protein 4;
GN   Name=KLHL4; Synonyms=KIAA1687;
//
ID   KLHL8_HUMAN             Reviewed;         620 AA.
AC   Q9P2G9; Q53XA3; Q6N018;
DE   RecName: Full=Kelch-like protein 8;
GN   Name=KLHL8; Synonyms=KIAA1378;
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   KLHL9_HUMAN             Reviewed;         617 AA.
AC   Q9P2J3; Q8TCQ2;
DE   RecName: Full=Kelch-like protein 9;
GN   Name=KLHL9; Synonyms=KIAA1354;
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   KLK10_HUMAN             Reviewed;         276 AA.
AC   O43240; A6NC12; Q53YL3; Q99920; Q9GZW9;
DE   RecName: Full=Kallikrein-10;
DE            EC=3.4.21.-;
DE   AltName: Full=Normal epithelial cell-specific 1;
DE   AltName: Full=Protease serine-like 1;
DE   Flags: Precursor;
GN   Name=KLK10; Synonyms=NES1, PRSSL1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   KLK11_HUMAN             Reviewed;         282 AA.
AC   Q9UBX7; O75837; Q0WXX5; Q8IXD7; Q9NS65;
DE   RecName: Full=Kallikrein-11;
DE            Short=hK11;
DE            EC=3.4.21.-;
DE   AltName: Full=Hippostasin;
DE   AltName: Full=Serine protease 20;
DE   AltName: Full=Trypsin-like protease;
DE   Contains:
DE     RecName: Full=Kallikrein-11 inactive chain 1;
DE   Contains:
DE     RecName: Full=Kallikrein-11 inactive chain 2;
DE   Flags: Precursor;
GN   Name=KLK11; Synonyms=PRSS20, TLSP; ORFNames=UNQ649/PRO1279;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   KLK12_HUMAN             Reviewed;         248 AA.
AC   Q9UKR0; Q9UKR1; Q9UKR2;
DE   RecName: Full=Kallikrein-12;
DE            EC=3.4.21.-;
DE   AltName: Full=Kallikrein-like protein 5;
DE            Short=KLK-L5;
DE   Flags: Precursor;
GN   Name=KLK12; Synonyms=KLKL5; ORFNames=UNQ669/PRO1303;
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   KLK13_HUMAN             Reviewed;         277 AA.
AC   Q9UKR3; A7UNK6; Q9Y433;
DE   RecName: Full=Kallikrein-13;
DE            EC=3.4.21.-;
DE   AltName: Full=Kallikrein-like protein 4;
DE            Short=KLK-L4;
DE   Flags: Precursor;
GN   Name=KLK13; Synonyms=KLKL4;
DR   GO; GO:0016787; F:hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   KLK14_HUMAN             Reviewed;         267 AA.
AC   Q9P0G3; A7UNK5; Q1RMZ2; Q6B089;
DE   RecName: Full=Kallikrein-14;
DE            Short=hK14;
DE            EC=3.4.21.-;
DE   AltName: Full=Kallikrein-like protein 6;
DE            Short=KLK-L6;
DE   Flags: Precursor;
GN   Name=KLK14; Synonyms=KLKL6;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0048730; P:epidermis morphogenesis; IDA:UniProtKB.
DR   GO; GO:0009566; P:fertilization; IDA:UniProtKB.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0070684; P:seminal clot liquefaction; IDA:UniProtKB.
//
ID   KLK15_HUMAN             Reviewed;         256 AA.
AC   Q9H2R5; A0AUY8; Q15358; Q6ISI0; Q9H2R3; Q9H2R4; Q9H2R6; Q9HBG9;
DE   RecName: Full=Kallikrein-15;
DE            EC=3.4.21.-;
DE   AltName: Full=ACO protease;
DE   Flags: Precursor;
GN   Name=KLK15;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   KLK1_HUMAN              Reviewed;         262 AA.
AC   P06870; Q66US9; Q86U61; Q8TCV8; Q9BS53; Q9NQU4; Q9UD19; Q9UMJ1;
DE   RecName: Full=Kallikrein-1;
DE            EC=3.4.21.35;
DE   AltName: Full=Kidney/pancreas/salivary gland kallikrein;
DE   AltName: Full=Tissue kallikrein;
DE   Flags: Precursor;
GN   Name=KLK1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
//
ID   KLK2_HUMAN              Reviewed;         261 AA.
AC   P20151; B4DU93; B4DUB0; F5H8L3; Q15946; Q9UJZ9;
DE   RecName: Full=Kallikrein-2;
DE            EC=3.4.21.35;
DE   AltName: Full=Glandular kallikrein-1;
DE            Short=hGK-1;
DE   AltName: Full=Tissue kallikrein-2;
DE   Flags: Precursor;
GN   Name=KLK2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   KLK3_HUMAN              Reviewed;         261 AA.
AC   P07288; C9JXH3; G3V0H4; G3XAE3; Q15096; Q16272; Q86TG8; Q8IXI4;
DE   RecName: Full=Prostate-specific antigen;
DE            Short=PSA;
DE            EC=3.4.21.77;
DE   AltName: Full=Gamma-seminoprotein;
DE            Short=Seminin;
DE   AltName: Full=Kallikrein-3;
DE   AltName: Full=P-30 antigen;
DE   AltName: Full=Semenogelase;
DE   Flags: Precursor;
GN   Name=KLK3; Synonyms=APS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; NAS:UniProtKB.
//
ID   KLK4_HUMAN              Reviewed;         254 AA.
AC   Q9Y5K2; Q4VB16; Q9GZL6; Q9UBJ6;
DE   RecName: Full=Kallikrein-4;
DE            EC=3.4.21.-;
DE   AltName: Full=Enamel matrix serine proteinase 1;
DE   AltName: Full=Kallikrein-like protein 1;
DE            Short=KLK-L1;
DE   AltName: Full=Prostase;
DE   AltName: Full=Serine protease 17;
DE   Flags: Precursor;
GN   Name=KLK4; Synonyms=EMSP1, PRSS17, PSTS;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB.
DR   GO; GO:0097186; P:amelogenesis; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   KLK5_HUMAN              Reviewed;         293 AA.
AC   Q9Y337; Q53ZR3; Q9HBG8;
DE   RecName: Full=Kallikrein-5;
DE            EC=3.4.21.-;
DE   AltName: Full=Kallikrein-like protein 2;
DE            Short=KLK-L2;
DE   AltName: Full=Stratum corneum tryptic enzyme;
DE   Flags: Precursor;
GN   Name=KLK5; Synonyms=SCTE; ORFNames=UNQ570/PRO1132;
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
//
ID   KLK7_HUMAN              Reviewed;         253 AA.
AC   P49862; A8K0U5; Q8N5N9; Q8NFV7;
DE   RecName: Full=Kallikrein-7;
DE            Short=hK7;
DE            EC=3.4.21.117;
DE   AltName: Full=Serine protease 6;
DE   AltName: Full=Stratum corneum chymotryptic enzyme;
DE            Short=hSCCE;
DE   Flags: Precursor;
GN   Name=KLK7; Synonyms=PRSS6, SCCE;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   KLK6_HUMAN              Reviewed;         244 AA.
AC   Q92876; A6NJA1; A8MW09; Q6H301;
DE   RecName: Full=Kallikrein-6;
DE            EC=3.4.21.-;
DE   AltName: Full=Neurosin;
DE   AltName: Full=Protease M;
DE   AltName: Full=SP59;
DE   AltName: Full=Serine protease 18;
DE   AltName: Full=Serine protease 9;
DE   AltName: Full=Zyme;
DE   Flags: Precursor;
GN   Name=KLK6; Synonyms=PRSS18, PRSS9;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0042982; P:amyloid precursor protein metabolic process; NAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; NAS:UniProtKB.
DR   GO; GO:0042445; P:hormone metabolic process; NAS:UniProtKB.
DR   GO; GO:0042552; P:myelination; NAS:UniProtKB.
DR   GO; GO:0070997; P:neuron death; IMP:UniProt.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016540; P:protein autoprocessing; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0045595; P:regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; NAS:UniProtKB.
DR   GO; GO:0042246; P:tissue regeneration; NAS:UniProtKB.
//
ID   KLK8_HUMAN              Reviewed;         260 AA.
AC   O60259; Q5V9X1; Q5V9X2; Q8IW69; Q9HCB3; Q9NR68; Q9NR69; Q9UIL9;
AC   Q9UQ47;
DE   RecName: Full=Kallikrein-8;
DE            Short=hK8;
DE            EC=3.4.21.118;
DE   AltName: Full=Neuropsin;
DE            Short=NP;
DE   AltName: Full=Ovasin;
DE   AltName: Full=Serine protease 19;
DE   AltName: Full=Serine protease TADG-14;
DE   AltName: Full=Tumor-associated differentially expressed gene 14 protein;
DE   Flags: Precursor;
GN   Name=KLK8; Synonyms=NRPN, PRSS19, TADG14; ORFNames=UNQ283/PRO322;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; ISS:UniProtKB.
DR   GO; GO:0043616; P:keratinocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0007613; P:memory; ISS:UniProtKB.
DR   GO; GO:0048681; P:negative regulation of axon regeneration; ISS:UniProtKB.
DR   GO; GO:0031642; P:negative regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050807; P:regulation of synapse organization; ISS:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; ISS:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
//
ID   KLK9_HUMAN              Reviewed;         250 AA.
AC   Q9UKQ9;
DE   RecName: Full=Kallikrein-9;
DE            EC=3.4.21.-;
DE   AltName: Full=Kallikrein-like protein 3;
DE            Short=KLK-L3;
DE   Flags: Precursor;
GN   Name=KLK9;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
//
ID   KLKB1_HUMAN             Reviewed;         638 AA.
AC   P03952; A6NH96; B2R8H9; Q17RE8; Q17RE9; Q4W5C3;
DE   RecName: Full=Plasma kallikrein;
DE            EC=3.4.21.34;
DE   AltName: Full=Fletcher factor;
DE   AltName: Full=Kininogenin;
DE   AltName: Full=Plasma prekallikrein;
DE   Contains:
DE     RecName: Full=Plasma kallikrein heavy chain;
DE   Contains:
DE     RecName: Full=Plasma kallikrein light chain;
DE   Flags: Precursor;
GN   Name=KLKB1; Synonyms=KLK3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0002542; P:Factor XII activation; TAS:BHF-UCL.
DR   GO; GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.
DR   GO; GO:0031639; P:plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0051919; P:positive regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0031638; P:zymogen activation; TAS:BHF-UCL.
//
ID   KLOTB_HUMAN             Reviewed;        1044 AA.
AC   Q86Z14; Q2M3K8;
DE   RecName: Full=Beta-klotho;
DE            Short=BKL;
DE            Short=BetaKlotho;
DE   AltName: Full=Klotho beta-like protein;
GN   Name=KLB;
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0090080; P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
//
ID   KLOT_HUMAN              Reviewed;        1012 AA.
AC   Q9UEF7; Q5VZ95; Q96KV5; Q96KW5; Q9UEI9; Q9Y4F0;
DE   RecName: Full=Klotho;
DE            EC=3.2.1.31;
DE   Contains:
DE     RecName: Full=Klotho peptide;
DE   Flags: Precursor;
GN   Name=KL;
DR   GO; GO:0008422; F:beta-glucosidase activity; TAS:ProtInc.
DR   GO; GO:0004566; F:beta-glucuronidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0005499; F:vitamin D binding; IEA:UniProtKB-KW.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IMP:UniProtKB.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006112; P:energy reserve metabolic process; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IMP:UniProtKB.
DR   GO; GO:0090080; P:positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
//
ID   KLRB1_HUMAN             Reviewed;         225 AA.
AC   Q12918; Q24K24;
DE   RecName: Full=Killer cell lectin-like receptor subfamily B member 1;
DE   AltName: Full=C-type lectin domain family 5 member B;
DE   AltName: Full=HNKR-P1a;
DE            Short=NKR-P1A;
DE   AltName: Full=Natural killer cell surface protein P1A;
DE   AltName: CD_antigen=CD161;
GN   Name=KLRB1; Synonyms=CLEC5B, NKRP1A;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
//
ID   KLRD1_HUMAN             Reviewed;         179 AA.
AC   Q13241; O43321; O43773; Q9UBE3; Q9UEQ0;
DE   RecName: Full=Natural killer cells antigen CD94;
DE   AltName: Full=KP43;
DE   AltName: Full=Killer cell lectin-like receptor subfamily D member 1;
DE   AltName: Full=NK cell receptor;
DE   AltName: CD_antigen=CD94;
GN   Name=KLRD1; Synonyms=CD94;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KLRF1_HUMAN             Reviewed;         232 AA.
AC   Q9NZS2; Q4KMT5; Q96PR2; Q96PR3; Q9NZS1;
DE   RecName: Full=Killer cell lectin-like receptor subfamily F member 1;
DE            Short=Lectin-like receptor F1;
DE   AltName: Full=Activating coreceptor NKp80;
DE   AltName: Full=C-type lectin domain family 5 member C;
GN   Name=KLRF1; Synonyms=CLEC5C, ML;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0032393; F:MHC class I receptor activity; TAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
//
ID   KLRF2_HUMAN             Reviewed;         207 AA.
AC   D3W0D1;
DE   RecName: Full=Killer cell lectin-like receptor subfamily F member 2;
DE            Short=Lectin-like receptor F2;
DE   AltName: Full=Activating coreceptor NKp65;
GN   Name=KLRF2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0050663; P:cytokine secretion; TAS:UniProtKB.
DR   GO; GO:0043320; P:natural killer cell degranulation; TAS:UniProtKB.
//
ID   KLRG1_HUMAN             Reviewed;         195 AA.
AC   Q96E93; B7ZAM2; O43198; O75613;
DE   RecName: Full=Killer cell lectin-like receptor subfamily G member 1;
DE   AltName: Full=C-type lectin domain family 15 member A;
DE   AltName: Full=ITIM-containing receptor MAFA-L;
DE   AltName: Full=MAFA-like receptor;
DE   AltName: Full=Mast cell function-associated antigen;
GN   Name=KLRG1; Synonyms=CLEC15A, MAFA, MAFAL;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KLRG2_HUMAN             Reviewed;         409 AA.
AC   A4D1S0; Q2NL79; Q6ZTV6;
DE   RecName: Full=Killer cell lectin-like receptor subfamily G member 2;
DE   AltName: Full=C-type lectin domain family 15 member B;
GN   Name=KLRG2; Synonyms=CLEC15B;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   KMCP1_HUMAN             Reviewed;         291 AA.
AC   Q5SVS4; B2RN96; B4DZK3; F5H8H8;
DE   RecName: Full=Kidney mitochondrial carrier protein 1;
DE   AltName: Full=Solute carrier family 25 member 30;
GN   Name=SLC25A30; Synonyms=KMCP1;
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
//
ID   KMO_HUMAN               Reviewed;         486 AA.
AC   O15229; A2A2U8; A2A2U9; A2A2V0; Q5SY07; Q5SY08; Q5SY09;
DE   RecName: Full=Kynurenine 3-monooxygenase;
DE            EC=1.14.13.9;
DE   AltName: Full=Kynurenine 3-hydroxylase;
GN   Name=KMO;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0004502; F:kynurenine 3-monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0016174; F:NAD(P)H oxidase activity; IDA:UniProtKB.
DR   GO; GO:0034354; P:'de novo' NAD biosynthetic process from tryptophan; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043420; P:anthranilate metabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0070189; P:kynurenine metabolic process; IDA:UniProtKB.
DR   GO; GO:0019805; P:quinolinate biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0009651; P:response to salt stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:Ensembl.
//
ID   KMT2A_HUMAN             Reviewed;        3969 AA.
AC   Q03164; E9PQG7; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1;
AC   Q9HBJ3; Q9UD94; Q9UMA3;
DE   RecName: Full=Histone-lysine N-methyltransferase 2A;
DE            Short=Lysine N-methyltransferase 2A;
DE            EC=2.1.1.43;
DE   AltName: Full=ALL-1;
DE   AltName: Full=CXXC-type zinc finger protein 7;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 1;
DE   AltName: Full=Trithorax-like protein;
DE   AltName: Full=Zinc finger protein HRX;
DE   Contains:
DE     RecName: Full=MLL cleavage product N320;
DE     AltName: Full=N-terminal cleavage product of 320 kDa;
DE              Short=p320;
DE   Contains:
DE     RecName: Full=MLL cleavage product C180;
DE     AltName: Full=C-terminal cleavage product of 180 kDa;
DE              Short=p180;
GN   Name=KMT2A; Synonyms=ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1;
DR   GO; GO:0003680; F:AT DNA binding; NAS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0045322; F:unmethylated CpG binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006306; P:DNA methylation; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; TAS:UniProtKB.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IDA:BHF-UCL.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2001040; P:positive regulation of cellular response to drug; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0032411; P:positive regulation of transporter activity; IMP:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0051569; P:regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   KMT2B_HUMAN             Reviewed;        2715 AA.
AC   Q9UMN6; O15022; O95836; Q96GP2; Q96IP3; Q9UK25; Q9Y668; Q9Y669;
DE   RecName: Full=Histone-lysine N-methyltransferase 2B;
DE            Short=Lysine N-methyltransferase 2B;
DE            EC=2.1.1.43;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 4;
DE   AltName: Full=Trithorax homolog 2;
DE   AltName: Full=WW domain-binding protein 7;
DE            Short=WBP-7;
GN   Name=KMT2B; Synonyms=HRX2, KIAA0304, MLL2, MLL4, TRX2, WBP7;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; NAS:UniProtKB.
DR   GO; GO:0016458; P:gene silencing; IEA:Ensembl.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IEA:Ensembl.
DR   GO; GO:0009994; P:oocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0030728; P:ovulation; IEA:Ensembl.
DR   GO; GO:0051569; P:regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KMT2C_HUMAN             Reviewed;        4911 AA.
AC   Q8NEZ4; Q8NC02; Q8NDF6; Q9H9P4; Q9NR13; Q9P222; Q9UDR7;
DE   RecName: Full=Histone-lysine N-methyltransferase 2C;
DE            Short=Lysine N-methyltransferase 2C;
DE            EC=2.1.1.43;
DE   AltName: Full=Homologous to ALR protein;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 3;
GN   Name=KMT2C; Synonyms=HALR, KIAA1506, MLL3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KMT2D_HUMAN             Reviewed;        5537 AA.
AC   O14686; O14687;
DE   RecName: Full=Histone-lysine N-methyltransferase 2D;
DE            Short=Lysine N-methyltransferase 2D;
DE            EC=2.1.1.43;
DE   AltName: Full=ALL1-related protein;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 2;
GN   Name=KMT2D; Synonyms=ALR, MLL2, MLL4;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006342; P:chromatin silencing; ISS:UniProtKB.
DR   GO; GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001555; P:oocyte growth; ISS:UniProtKB.
DR   GO; GO:0048477; P:oogenesis; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KMT2E_HUMAN             Reviewed;        1858 AA.
AC   Q8IZD2; B6ZDE4; B6ZDM3; M4K8J3; Q6P5Y2; Q6PKG4; Q6T316; Q86TI3;
AC   Q86W12; Q86WG0; Q86WL2; Q8IV78; Q8IWR5; Q8NFF8; Q9NWE7;
DE   RecName: Full=Histone-lysine N-methyltransferase 2E;
DE            Short=Lysine N-methyltransferase 2E;
DE            EC=2.1.1.43;
DE   AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 5;
GN   Name=KMT2E; Synonyms=MLL5;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IDA:BHF-UCL.
DR   GO; GO:0006306; P:DNA methylation; ISS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:BHF-UCL.
DR   GO; GO:0042119; P:neutrophil activation; ISS:UniProtKB.
DR   GO; GO:0002446; P:neutrophil mediated immunity; ISS:UniProtKB.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KNCN_HUMAN              Reviewed;         124 AA.
AC   A6PVL3; A8MXE3;
DE   RecName: Full=Kinocilin;
GN   Name=KNCN;
//
ID   KNG1_HUMAN              Reviewed;         644 AA.
AC   P01042; A8K474; B2RCR2; C9JEX1; P01043; Q53EQ0; Q6PAU9; Q7M4P1;
DE   RecName: Full=Kininogen-1;
DE   AltName: Full=Alpha-2-thiol proteinase inhibitor;
DE   AltName: Full=Fitzgerald factor;
DE   AltName: Full=High molecular weight kininogen;
DE            Short=HMWK;
DE   AltName: Full=Williams-Fitzgerald-Flaujeac factor;
DE   Contains:
DE     RecName: Full=Kininogen-1 heavy chain;
DE   Contains:
DE     RecName: Full=T-kinin;
DE     AltName: Full=Ile-Ser-Bradykinin;
DE   Contains:
DE     RecName: Full=Bradykinin;
DE     AltName: Full=Kallidin I;
DE   Contains:
DE     RecName: Full=Lysyl-bradykinin;
DE     AltName: Full=Kallidin II;
DE   Contains:
DE     RecName: Full=Kininogen-1 light chain;
DE   Contains:
DE     RecName: Full=Low molecular weight growth-promoting factor;
DE   Flags: Precursor;
GN   Name=KNG1; Synonyms=BDK, KNG;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:UniProt.
DR   GO; GO:0008201; F:heparin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IDA:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:UniProt.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; TAS:UniProtKB.
DR   GO; GO:0035810; P:positive regulation of urine volume; TAS:UniProtKB.
DR   GO; GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
DR   GO; GO:0042311; P:vasodilation; IEA:UniProtKB-KW.
//
ID   KNOP1_HUMAN             Reviewed;         458 AA.
AC   Q1ED39; O43328; Q5FWF3;
DE   RecName: Full=Lysine-rich nucleolar protein 1;
DE   AltName: Full=Protein FAM191A;
DE   AltName: Full=Testis-specific gene 118 protein;
GN   Name=KNOP1; Synonyms=C16orf88, FAM191A, TSG118;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   KNTC1_HUMAN             Reviewed;        2209 AA.
AC   P50748; A7E2C4;
DE   RecName: Full=Kinetochore-associated protein 1;
DE   AltName: Full=Rough deal homolog;
DE            Short=HsROD;
DE            Short=Rod;
DE            Short=hRod;
GN   Name=KNTC1; Synonyms=KIAA0166;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0007096; P:regulation of exit from mitosis; NAS:UniProtKB.
//
ID   KPB1_HUMAN              Reviewed;        1223 AA.
AC   P46020; B7ZL05; B7ZL07; Q2M3D7;
DE   RecName: Full=Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform;
DE            Short=Phosphorylase kinase alpha M subunit;
GN   Name=PHKA1; Synonyms=PHKA;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0004689; F:phosphorylase kinase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KPB2_HUMAN              Reviewed;        1235 AA.
AC   P46019; A8K1T1; Q6LAJ5; Q7Z6W0; Q96CR3; Q9UDA1;
DE   RecName: Full=Phosphorylase b kinase regulatory subunit alpha, liver isoform;
DE            Short=Phosphorylase kinase alpha L subunit;
GN   Name=PHKA2; Synonyms=PHKLA, PYK;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0004689; F:phosphorylase kinase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KPBB_HUMAN              Reviewed;        1093 AA.
AC   Q93100; Q8N4T5;
DE   RecName: Full=Phosphorylase b kinase regulatory subunit beta;
DE            Short=Phosphorylase kinase subunit beta;
GN   Name=PHKB;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0004689; F:phosphorylase kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KPCA_HUMAN              Reviewed;         672 AA.
AC   P17252; B5BU22; Q15137; Q32M72; Q96RE4;
DE   RecName: Full=Protein kinase C alpha type;
DE            Short=PKC-A;
DE            Short=PKC-alpha;
DE            EC=2.7.11.13;
GN   Name=PRKCA; Synonyms=PKCA, PRKACA;
DR   GuidetoPHARMACOLOGY; 1482; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004698; F:calcium-dependent protein kinase C activity; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004697; F:protein kinase C activity; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; ISS:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071322; P:cellular response to carbohydrate stimulus; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002159; P:desmosome assembly; IMP:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035408; P:histone H3-T6 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0046325; P:negative regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0036289; P:peptidyl-serine autophosphorylation; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:Ensembl.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0090330; P:regulation of platelet aggregation; IDA:UniProtKB.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KPCB_HUMAN              Reviewed;         671 AA.
AC   P05771; C5IFJ8; D3DWF5; O43744; P05127; Q15138; Q93060; Q9UE49;
AC   Q9UE50; Q9UEH8; Q9UJ30; Q9UJ33;
DE   RecName: Full=Protein kinase C beta type;
DE            Short=PKC-B;
DE            Short=PKC-beta;
DE            EC=2.7.11.13;
GN   Name=PRKCB; Synonyms=PKCB, PRKCB1;
DR   GuidetoPHARMACOLOGY; 1483; -.
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004697; F:protein kinase C activity; TAS:ProtInc.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0042113; P:B cell activation; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071322; P:cellular response to carbohydrate stimulus; IEA:Ensembl.
DR   GO; GO:0035408; P:histone H3-T6 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0042953; P:lipoprotein transport; TAS:BHF-UCL.
DR   GO; GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   KPCD1_HUMAN             Reviewed;         912 AA.
AC   Q15139; A6NL64; B2RAF6;
DE   RecName: Full=Serine/threonine-protein kinase D1;
DE            EC=2.7.11.13;
DE   AltName: Full=Protein kinase C mu type;
DE   AltName: Full=Protein kinase D;
DE   AltName: Full=nPKC-D1;
DE   AltName: Full=nPKC-mu;
GN   Name=PRKD1; Synonyms=PKD, PKD1, PRKCM;
DR   GuidetoPHARMACOLOGY; 1489; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:BHF-UCL.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.
DR   GO; GO:0045806; P:negative regulation of endocytosis; TAS:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.
DR   GO; GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0038033; P:positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IGI:BHF-UCL.
DR   GO; GO:1901727; P:positive regulation of histone deacetylase activity; IGI:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IGI:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:BHF-UCL.
DR   GO; GO:2001044; P:regulation of integrin-mediated signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   KPCD2_HUMAN             Reviewed;         878 AA.
AC   Q9BZL6; Q8TB08; Q9P0T6; Q9Y3X8;
DE   RecName: Full=Serine/threonine-protein kinase D2;
DE            EC=2.7.11.13;
DE   AltName: Full=nPKC-D2;
GN   Name=PRKD2; Synonyms=PKD2; ORFNames=HSPC187;
DR   GuidetoPHARMACOLOGY; 2173; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IMP:BHF-UCL.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0061154; P:endothelial tube morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.
DR   GO; GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0038033; P:positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:1901727; P:positive regulation of histone deacetylase activity; IGI:BHF-UCL.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; ISS:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IMP:UniProtKB.
DR   GO; GO:1902533; P:positive regulation of intracellular signal transduction; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IGI:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   KPCD3_HUMAN             Reviewed;         890 AA.
AC   O94806; D6W587; Q53TR7; Q8NEL8;
DE   RecName: Full=Serine/threonine-protein kinase D3;
DE            EC=2.7.11.13;
DE   AltName: Full=Protein kinase C nu type;
DE   AltName: Full=Protein kinase EPK2;
DE   AltName: Full=nPKC-nu;
GN   Name=PRKD3; Synonyms=EPK2, PRKCN;
DR   GuidetoPHARMACOLOGY; 2174; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004697; F:protein kinase C activity; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   KPCD_HUMAN              Reviewed;         676 AA.
AC   Q05655; B0KZ81; B2R834; Q15144; Q86XJ6;
DE   RecName: Full=Protein kinase C delta type;
DE            EC=2.7.11.13;
DE   AltName: Full=Tyrosine-protein kinase PRKCD;
DE            EC=2.7.10.2;
DE   AltName: Full=nPKC-delta;
DE   Contains:
DE     RecName: Full=Protein kinase C delta type regulatory subunit;
DE   Contains:
DE     RecName: Full=Protein kinase C delta type catalytic subunit;
DE     AltName: Full=Sphingosine-dependent protein kinase-1;
DE              Short=SDK1;
GN   Name=PRKCD;
DR   GuidetoPHARMACOLOGY; 1485; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004699; F:calcium-independent protein kinase C activity; TAS:BHF-UCL.
DR   GO; GO:0008047; F:enzyme activator activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004697; F:protein kinase C activity; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0042100; P:B cell proliferation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0090398; P:cellular senescence; IMP:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032613; P:interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032615; P:interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; TAS:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042119; P:neutrophil activation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:2000304; P:positive regulation of ceramide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:2000753; P:positive regulation of glucosylceramide catabolic process; IMP:BHF-UCL.
DR   GO; GO:1900163; P:positive regulation of phospholipid scramblase activity; IMP:UniProtKB.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:2000755; P:positive regulation of sphingomyelin catabolic process; IMP:BHF-UCL.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; NAS:UniProtKB.
DR   GO; GO:0010469; P:regulation of receptor activity; TAS:BHF-UCL.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0023021; P:termination of signal transduction; IMP:BHF-UCL.
//
ID   KPCE_HUMAN              Reviewed;         737 AA.
AC   Q02156; B0LPH7; Q32MQ3; Q53SL4; Q53SM5; Q9UE81;
DE   RecName: Full=Protein kinase C epsilon type;
DE            EC=2.7.11.13;
DE   AltName: Full=nPKC-epsilon;
GN   Name=PRKCE; Synonyms=PKCE;
DR   GuidetoPHARMACOLOGY; 1486; -.
DR   GO; GO:0003785; F:actin monomer binding; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004699; F:calcium-independent protein kinase C activity; IEA:Ensembl.
DR   GO; GO:0008047; F:enzyme activator activity; IMP:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0035276; F:ethanol binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004697; F:protein kinase C activity; IDA:BHF-UCL.
DR   GO; GO:0030546; F:receptor activator activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0002281; P:macrophage activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:2001031; P:positive regulation of cellular glucuronidation; IMP:BHF-UCL.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0050996; P:positive regulation of lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0070257; P:positive regulation of mucus secretion; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0090303; P:positive regulation of wound healing; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; ISS:UniProtKB.
//
ID   KPCG_HUMAN              Reviewed;         697 AA.
AC   P05129;
DE   RecName: Full=Protein kinase C gamma type;
DE            Short=PKC-gamma;
DE            EC=2.7.11.13;
GN   Name=PRKCG; Synonyms=PKCG;
DR   GuidetoPHARMACOLOGY; 1484; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004698; F:calcium-dependent protein kinase C activity; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; IDA:HGNC.
DR   GO; GO:0004697; F:protein kinase C activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007635; P:chemosensory behavior; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:HGNC.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:HGNC.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016310; P:phosphorylation; IDA:HGNC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0032425; P:positive regulation of mismatch repair; IDA:HGNC.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0043278; P:response to morphine; ISS:UniProtKB.
DR   GO; GO:0048265; P:response to pain; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KPCI_HUMAN              Reviewed;         596 AA.
AC   P41743; D3DNQ4; Q8WW06;
DE   RecName: Full=Protein kinase C iota type;
DE            EC=2.7.11.13;
DE   AltName: Full=Atypical protein kinase C-lambda/iota;
DE            Short=PRKC-lambda/iota;
DE            Short=aPKC-lambda/iota;
DE   AltName: Full=nPKC-iota;
GN   Name=PRKCI; Synonyms=DXS1179E;
DR   GuidetoPHARMACOLOGY; 1490; -.
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004697; F:protein kinase C activity; ISS:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; IMP:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0035089; P:establishment of apical/basal cell polarity; IEA:Ensembl.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; TAS:UniProtKB.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0048194; P:Golgi vesicle budding; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; NAS:UniProtKB.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0046903; P:secretion; NAS:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
//
ID   KPCL_HUMAN              Reviewed;         683 AA.
AC   P24723; Q16246; Q8NE03;
DE   RecName: Full=Protein kinase C eta type;
DE            EC=2.7.11.13;
DE   AltName: Full=PKC-L;
DE   AltName: Full=nPKC-eta;
GN   Name=PRKCH; Synonyms=PKCL, PRKCL;
DR   GuidetoPHARMACOLOGY; 1487; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004699; F:calcium-independent protein kinase C activity; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004697; F:protein kinase C activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0070528; P:protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KPCT_HUMAN              Reviewed;         706 AA.
AC   Q04759; B4DF52; Q14DH6; Q3MJF1; Q64FY5; Q9H508; Q9H549;
DE   RecName: Full=Protein kinase C theta type;
DE            EC=2.7.11.13;
DE   AltName: Full=nPKC-theta;
GN   Name=PRKCQ; Synonyms=PRKCT;
DR   GuidetoPHARMACOLOGY; 1488; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; ISS:BHF-UCL.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0070233; P:negative regulation of T cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.
DR   GO; GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:GOC.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   KPCZ_HUMAN              Reviewed;         592 AA.
AC   Q05513; A8K4N0; A8MU64; B7Z2J7; E9PCW2; Q15207; Q5SYT5; Q969S4;
DE   RecName: Full=Protein kinase C zeta type;
DE            EC=2.7.11.13;
DE   AltName: Full=nPKC-zeta;
GN   Name=PRKCZ; Synonyms=PKC2;
DR   GuidetoPHARMACOLOGY; 1491; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043560; F:insulin receptor substrate binding; IC:BHF-UCL.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
DR   GO; GO:0031584; P:activation of phospholipase D activity; IEA:Ensembl.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0051346; P:negative regulation of hydrolase activity; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:2001181; P:positive regulation of interleukin-10 secretion; ISS:UniProtKB.
DR   GO; GO:2000667; P:positive regulation of interleukin-13 secretion; ISS:UniProtKB.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:2000664; P:positive regulation of interleukin-5 secretion; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:UniProtKB.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0070528; P:protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IEA:Ensembl.
//
ID   KPRA_HUMAN              Reviewed;         356 AA.
AC   Q14558; B2R6M4; Q96H06;
DE   RecName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1;
DE            Short=PRPP synthase-associated protein 1;
DE   AltName: Full=39 kDa phosphoribosypyrophosphate synthase-associated protein;
DE            Short=PAP39;
GN   Name=PRPSAP1;
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
//
ID   KPRB_HUMAN              Reviewed;         369 AA.
AC   O60256; B4E1M8; B4E329; B7ZKZ1; E7EMY2; Q6IAS2;
DE   RecName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 2;
DE            Short=PRPP synthase-associated protein 2;
DE   AltName: Full=41 kDa phosphoribosypyrophosphate synthetase-associated protein;
DE            Short=PAP41;
GN   Name=PRPSAP2;
DR   GO; GO:0004857; F:enzyme inhibitor activity; TAS:ProtInc.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:InterPro.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:InterPro.
//
ID   KPRP_HUMAN              Reviewed;         579 AA.
AC   Q5T749;
DE   RecName: Full=Keratinocyte proline-rich protein;
DE            Short=hKPRP;
GN   Name=KPRP; Synonyms=C1orf45;
//
ID   KPSH1_HUMAN             Reviewed;         424 AA.
AC   P11801; Q9NY19;
DE   RecName: Full=Serine/threonine-protein kinase H1;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein serine kinase H1;
DE            Short=PSK-H1;
GN   Name=PSKH1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   KPSH2_HUMAN             Reviewed;         385 AA.
AC   Q96QS6; A0AV22;
DE   RecName: Full=Serine/threonine-protein kinase H2;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein serine kinase H2;
DE            Short=PSK-H2;
GN   Name=PSKH2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   KPTN_HUMAN              Reviewed;         436 AA.
AC   Q9Y664; B3KN86; B4DQ76; Q96GT1;
DE   RecName: Full=Kaptin;
DE   AltName: Full=Actin-associated protein 2E4;
GN   Name=KPTN;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0007015; P:actin filament organization; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007605; P:sensory perception of sound; NAS:ProtInc.
//
ID   KPYM_HUMAN              Reviewed;         531 AA.
AC   P14618; A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; P14786; Q53GK4;
AC   Q96E76; Q9BWB5; Q9UCV6; Q9UPF2;
DE   RecName: Full=Pyruvate kinase PKM;
DE            EC=2.7.1.40;
DE   AltName: Full=Cytosolic thyroid hormone-binding protein;
DE            Short=CTHBP;
DE   AltName: Full=Opa-interacting protein 3;
DE            Short=OIP-3;
DE   AltName: Full=Pyruvate kinase 2/3;
DE   AltName: Full=Pyruvate kinase muscle isozyme;
DE   AltName: Full=Thyroid hormone-binding protein 1;
DE            Short=THBP1;
DE   AltName: Full=Tumor M2-PK;
DE   AltName: Full=p58;
GN   Name=PKM; Synonyms=OIP3, PK2, PK3, PKM2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0023026; F:MHC class II protein complex binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004743; F:pyruvate kinase activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0012501; P:programmed cell death; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KPYR_HUMAN              Reviewed;         574 AA.
AC   P30613; P11973;
DE   RecName: Full=Pyruvate kinase PKLR;
DE            EC=2.7.1.40;
DE   AltName: Full=Pyruvate kinase 1;
DE   AltName: Full=Pyruvate kinase isozymes L/R;
DE   AltName: Full=R-type/L-type pyruvate kinase;
DE   AltName: Full=Red cell/liver pyruvate kinase;
GN   Name=PKLR; Synonyms=PK1, PKL;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0004743; F:pyruvate kinase activity; TAS:ProtInc.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0051707; P:response to other organism; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KR102_HUMAN             Reviewed;         255 AA.
AC   P60368; Q70LJ5;
DE   RecName: Full=Keratin-associated protein 10-2;
DE   AltName: Full=High sulfur keratin-associated protein 10.2;
DE   AltName: Full=Keratin-associated protein 10.2;
DE   AltName: Full=Keratin-associated protein 18-2;
DE   AltName: Full=Keratin-associated protein 18.2;
GN   Name=KRTAP10-2;
GN   Synonyms=KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2;
//
ID   KR101_HUMAN             Reviewed;         282 AA.
AC   P60331; Q0VAR0; Q0VAR1;
DE   RecName: Full=Keratin-associated protein 10-1;
DE   AltName: Full=High sulfur keratin-associated protein 10.1;
DE   AltName: Full=Keratin-associated protein 10.1;
DE   AltName: Full=Keratin-associated protein 18-1;
DE   AltName: Full=Keratin-associated protein 18.1;
GN   Name=KRTAP10-1;
GN   Synonyms=KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1;
//
ID   KR103_HUMAN             Reviewed;         221 AA.
AC   P60369; A3KN67; Q70LJ4;
DE   RecName: Full=Keratin-associated protein 10-3;
DE   AltName: Full=High sulfur keratin-associated protein 10.3;
DE   AltName: Full=Keratin-associated protein 10.3;
DE   AltName: Full=Keratin-associated protein 18-3;
DE   AltName: Full=Keratin-associated protein 18.3;
GN   Name=KRTAP10-3;
GN   Synonyms=KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3;
//
ID   KR104_HUMAN             Reviewed;         401 AA.
AC   P60372; Q08AS0;
DE   RecName: Full=Keratin-associated protein 10-4;
DE   AltName: Full=High sulfur keratin-associated protein 10.4;
DE   AltName: Full=Keratin-associated protein 10.4;
DE   AltName: Full=Keratin-associated protein 18-4;
DE   AltName: Full=Keratin-associated protein 18.4;
GN   Name=KRTAP10-4;
GN   Synonyms=KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4;
//
ID   KR105_HUMAN             Reviewed;         271 AA.
AC   P60370; Q0VAR7; Q0VAR8; Q70LJ3;
DE   RecName: Full=Keratin-associated protein 10-5;
DE   AltName: Full=High sulfur keratin-associated protein 10.5;
DE   AltName: Full=Keratin-associated protein 10.5;
DE   AltName: Full=Keratin-associated protein 18-5;
DE   AltName: Full=Keratin-associated protein 18.5;
GN   Name=KRTAP10-5;
GN   Synonyms=KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5;
//
ID   KR106_HUMAN             Reviewed;         365 AA.
AC   P60371;
DE   RecName: Full=Keratin-associated protein 10-6;
DE   AltName: Full=High sulfur keratin-associated protein 10.6;
DE   AltName: Full=Keratin-associated protein 10.6;
DE   AltName: Full=Keratin-associated protein 18-6;
DE   AltName: Full=Keratin-associated protein 18.6;
GN   Name=KRTAP10-6;
GN   Synonyms=KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6;
//
ID   KR107_HUMAN             Reviewed;         375 AA.
AC   P60409; Q0VDJ8; Q70LJ2;
DE   RecName: Full=Keratin-associated protein 10-7;
DE   AltName: Full=High sulfur keratin-associated protein 10.7;
DE   AltName: Full=Keratin-associated protein 10.7;
DE   AltName: Full=Keratin-associated protein 18-7;
DE   AltName: Full=Keratin-associated protein 18.7;
GN   Name=KRTAP10-7;
GN   Synonyms=KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7;
//
ID   KR108_HUMAN             Reviewed;         259 AA.
AC   P60410; A0JNW4;
DE   RecName: Full=Keratin-associated protein 10-8;
DE   AltName: Full=High sulfur keratin-associated protein 10.8;
DE   AltName: Full=Keratin-associated protein 10.8;
DE   AltName: Full=Keratin-associated protein 18-8;
DE   AltName: Full=Keratin-associated protein 18.8;
GN   Name=KRTAP10-8;
GN   Synonyms=KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8;
//
ID   KR109_HUMAN             Reviewed;         292 AA.
AC   P60411; A2RRG1; A6NIR9; Q70LJ1;
DE   RecName: Full=Keratin-associated protein 10-9;
DE   AltName: Full=High sulfur keratin-associated protein 10.9;
DE   AltName: Full=Keratin-associated protein 10.9;
DE   AltName: Full=Keratin-associated protein 18-9;
DE   AltName: Full=Keratin-associated protein 18.9;
GN   Name=KRTAP10-9;
GN   Synonyms=KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9;
//
ID   KR10A_HUMAN             Reviewed;         251 AA.
AC   P60014;
DE   RecName: Full=Keratin-associated protein 10-10;
DE   AltName: Full=High sulfur keratin-associated protein 10.10;
DE   AltName: Full=Keratin-associated protein 10.10;
DE   AltName: Full=Keratin-associated protein 18-10;
DE   AltName: Full=Keratin-associated protein 18.10;
GN   Name=KRTAP10-10;
GN   Synonyms=KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10;
//
ID   KR10C_HUMAN             Reviewed;         245 AA.
AC   P60413; B2RPA3;
DE   RecName: Full=Keratin-associated protein 10-12;
DE   AltName: Full=High sulfur keratin-associated protein 10.12;
DE   AltName: Full=Keratin-associated protein 10.12;
DE   AltName: Full=Keratin-associated protein 18-12;
DE   AltName: Full=Keratin-associated protein 18.12;
GN   Name=KRTAP10-12;
GN   Synonyms=KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12;
//
ID   KR10B_HUMAN             Reviewed;         298 AA.
AC   P60412; A2RRF9;
DE   RecName: Full=Keratin-associated protein 10-11;
DE   AltName: Full=High sulfur keratin-associated protein 10.11;
DE   AltName: Full=Keratin-associated protein 10.11;
DE   AltName: Full=Keratin-associated protein 18-11;
DE   AltName: Full=Keratin-associated protein 18.11;
GN   Name=KRTAP10-11;
GN   Synonyms=KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11;
//
ID   KR111_HUMAN             Reviewed;         163 AA.
AC   Q8IUC1; A1L4I8;
DE   RecName: Full=Keratin-associated protein 11-1;
DE   AltName: Full=High sulfur keratin-associated protein 11.1;
GN   Name=KRTAP11-1; Synonyms=KAP11.1, KRTAP11.1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KR121_HUMAN             Reviewed;          96 AA.
AC   P59990; Q0VAS3;
DE   RecName: Full=Keratin-associated protein 12-1;
DE   AltName: Full=High sulfur keratin-associated protein 12.1;
DE   AltName: Full=Keratin-associated protein 12.1;
GN   Name=KRTAP12-1; Synonyms=KAP12.1, KRTAP12.1;
//
ID   KR124_HUMAN             Reviewed;         112 AA.
AC   P60329; Q08AF5;
DE   RecName: Full=Keratin-associated protein 12-4;
DE   AltName: Full=High sulfur keratin-associated protein 12.4;
DE   AltName: Full=Keratin-associated protein 12.4;
GN   Name=KRTAP12-4; Synonyms=KAP12.4, KRTAP12.4;
//
ID   KR123_HUMAN             Reviewed;          96 AA.
AC   P60328;
DE   RecName: Full=Keratin-associated protein 12-3;
DE   AltName: Full=High sulfur keratin-associated protein 12.3;
DE   AltName: Full=Keratin-associated protein 12.3;
GN   Name=KRTAP12-3; Synonyms=KAP12.3, KRTAP12.3;
//
ID   KR131_HUMAN             Reviewed;         172 AA.
AC   Q8IUC0; Q14D20; Q3LI79;
DE   RecName: Full=Keratin-associated protein 13-1;
DE   AltName: Full=High sulfur keratin-associated protein 13.1;
GN   Name=KRTAP13-1; Synonyms=KAP13.1, KRTAP13.1;
//
ID   KR132_HUMAN             Reviewed;         175 AA.
AC   Q52LG2;
DE   RecName: Full=Keratin-associated protein 13-2;
GN   Name=KRTAP13-2; Synonyms=KAP13.2;
//
ID   KR122_HUMAN             Reviewed;         146 AA.
AC   P59991; A6NIS1; A6NMS9; Q0VAS4;
DE   RecName: Full=Keratin-associated protein 12-2;
DE   AltName: Full=High sulfur keratin-associated protein 12.2;
DE   AltName: Full=Keratin-associated protein 12.2;
GN   Name=KRTAP12-2; Synonyms=KAP12.2, KRTAP12.2;
//
ID   KR134_HUMAN             Reviewed;         160 AA.
AC   Q3LI77; A2RRL3;
DE   RecName: Full=Keratin-associated protein 13-4;
GN   Name=KRTAP13-4; Synonyms=KAP13.4;
//
ID   KR133_HUMAN             Reviewed;         172 AA.
AC   Q3SY46; Q3LI78;
DE   RecName: Full=Keratin-associated protein 13-3;
GN   Name=KRTAP13-3; Synonyms=KAP13.3;
//
ID   KR151_HUMAN             Reviewed;         137 AA.
AC   Q3LI76; Q2M3F4;
DE   RecName: Full=Keratin-associated protein 15-1;
GN   Name=KRTAP15-1; Synonyms=KAP15.1;
//
ID   KR161_HUMAN             Reviewed;         517 AA.
AC   A8MUX0;
DE   RecName: Full=Keratin-associated protein 16-1;
GN   Name=KRTAP16-1; Synonyms=KAP16.1;
//
ID   KR191_HUMAN             Reviewed;          90 AA.
AC   Q8IUB9; A4QN27; Q3LI75;
DE   RecName: Full=Keratin-associated protein 19-1;
DE   AltName: Full=High tyrosine-glycine keratin-associated protein 19.1;
GN   Name=KRTAP19-1; Synonyms=KAP19.1, KRTAP19.1;
//
ID   KR171_HUMAN             Reviewed;         105 AA.
AC   Q9BYP8;
DE   RecName: Full=Keratin-associated protein 17-1;
DE   AltName: Full=Keratin-associated protein 16.1;
GN   Name=KRTAP17-1; Synonyms=KAP17.1, KRTAP16.1;
//
ID   KR192_HUMAN             Reviewed;          52 AA.
AC   Q3LHN2;
DE   RecName: Full=Keratin-associated protein 19-2;
GN   Name=KRTAP19-2; Synonyms=KAP19.2;
//
ID   KR194_HUMAN             Reviewed;          84 AA.
AC   Q3LI73; Q17RT4; Q17RT6;
DE   RecName: Full=Keratin-associated protein 19-4;
GN   Name=KRTAP19-4; Synonyms=KAP19.4;
//
ID   KR193_HUMAN             Reviewed;          81 AA.
AC   Q7Z4W3;
DE   RecName: Full=Keratin-associated protein 19-3;
DE   AltName: Full=GTHRP;
DE   AltName: Full=Glycine/tyrosine-rich protein;
GN   Name=KRTAP19-3; Synonyms=KAP19.3;
//
ID   KR195_HUMAN             Reviewed;          72 AA.
AC   Q3LI72; A4IF22;
DE   RecName: Full=Keratin-associated protein 19-5;
GN   Name=KRTAP19-5; Synonyms=KAP19.5;
//
ID   KR196_HUMAN             Reviewed;          58 AA.
AC   Q3LI70; Q3LI71;
DE   RecName: Full=Keratin-associated protein 19-6;
GN   Name=KRTAP19-6; Synonyms=KAP19.6;
//
ID   KR197_HUMAN             Reviewed;          63 AA.
AC   Q3SYF9; Q08EP7;
DE   RecName: Full=Keratin-associated protein 19-7;
GN   Name=KRTAP19-7; Synonyms=KAP19.7;
//
ID   KR198_HUMAN             Reviewed;          63 AA.
AC   Q3LI54;
DE   RecName: Full=Keratin-associated protein 19-8;
GN   Name=KRTAP19-8; Synonyms=KAP19.8;
//
ID   KR202_HUMAN             Reviewed;          65 AA.
AC   Q3LI61;
DE   RecName: Full=Keratin-associated protein 20-2;
GN   Name=KRTAP20-2; Synonyms=KAP20.2;
//
ID   KR203_HUMAN             Reviewed;          44 AA.
AC   Q3LI60;
DE   RecName: Full=Keratin-associated protein 20-3;
GN   Name=KRTAP20-3; Synonyms=KAP20.3;
//
ID   KR204_HUMAN             Reviewed;          44 AA.
AC   Q3LI62;
DE   RecName: Full=Putative keratin-associated protein 20-4;
GN   Name=KRTAP20-4; Synonyms=KAP20.4;
//
ID   KR211_HUMAN             Reviewed;          79 AA.
AC   Q3LI58;
DE   RecName: Full=Keratin-associated protein 21-1;
GN   Name=KRTAP21-1; Synonyms=KAP21.1;
//
ID   KR201_HUMAN             Reviewed;          56 AA.
AC   Q3LI63;
DE   RecName: Full=Keratin-associated protein 20-1;
GN   Name=KRTAP20-1; Synonyms=KAP20.1;
//
ID   KR212_HUMAN             Reviewed;          83 AA.
AC   Q3LI59;
DE   RecName: Full=Keratin-associated protein 21-2;
GN   Name=KRTAP21-2; Synonyms=KAP21.2;
//
ID   KR213_HUMAN             Reviewed;          58 AA.
AC   Q3LHN1;
DE   RecName: Full=Keratin-associated protein 21-3;
GN   Name=KRTAP21-3; Synonyms=KAP21.3;
//
ID   KR222_HUMAN             Reviewed;          45 AA.
AC   Q3LI68;
DE   RecName: Full=Keratin-associated protein 22-2;
GN   Name=KRTAP22-2; Synonyms=KAP22.2;
//
ID   KR231_HUMAN             Reviewed;          65 AA.
AC   A1A580;
DE   RecName: Full=Keratin-associated protein 23-1;
GN   Name=KRTAP23-1; Synonyms=KAP23.1;
//
ID   KR241_HUMAN             Reviewed;         254 AA.
AC   Q3LI83; Q1XDX0;
DE   RecName: Full=Keratin-associated protein 24-1;
GN   Name=KRTAP24-1; Synonyms=KAP24.1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KR221_HUMAN             Reviewed;          48 AA.
AC   Q3MIV0;
DE   RecName: Full=Keratin-associated protein 22-1;
GN   Name=KRTAP22-1; Synonyms=KAP22.1;
//
ID   KR251_HUMAN             Reviewed;         102 AA.
AC   Q3LHN0;
DE   RecName: Full=Keratin-associated protein 25-1;
GN   Name=KRTAP25-1; Synonyms=KAP25.1;
//
ID   KR261_HUMAN             Reviewed;         210 AA.
AC   Q6PEX3; B0RZD3;
DE   RecName: Full=Keratin-associated protein 26-1;
GN   Name=KRTAP26-1; Synonyms=KAP26.1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   KR271_HUMAN             Reviewed;         207 AA.
AC   Q3LI81;
DE   RecName: Full=Keratin-associated protein 27-1;
GN   Name=KRTAP27-1; Synonyms=KAP27.1;
//
ID   KR291_HUMAN             Reviewed;         341 AA.
AC   A8MX34;
DE   RecName: Full=Keratin-associated protein 29-1;
DE   AltName: Full=Keratin-associated protein 29.2;
GN   Name=KRTAP29-1; Synonyms=KAP29.2;
//
ID   KR411_HUMAN             Reviewed;         195 AA.
AC   Q9BYQ6; A0AUY2;
DE   RecName: Full=Keratin-associated protein 4-11;
DE   AltName: Full=Keratin-associated protein 4-14;
DE   AltName: Full=Keratin-associated protein 4.11;
DE   AltName: Full=Keratin-associated protein 4.14;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.14;
GN   Name=KRTAP4-11; Synonyms=KAP4.14, KRTAP4-14, KRTAP4.11, KRTAP4.14;
//
ID   KR412_HUMAN             Reviewed;         201 AA.
AC   Q9BQ66; A3KMC5; Q495I0;
DE   RecName: Full=Keratin-associated protein 4-12;
DE   AltName: Full=Keratin-associated protein 4.12;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.12;
GN   Name=KRTAP4-12; Synonyms=KAP4.12, KRTAP4.12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   KR87P_HUMAN             Reviewed;         255 AA.
AC   A6NCN2; B4DTA1;
DE   RecName: Full=Putative keratin-87 protein;
DE   AltName: Full=Keratin, hair, basic pseudogene 4;
DE   AltName: Full=Keratin-121 pseudogene;
GN   Name=KRT87P; Synonyms=KRT121P, KRTHBP4;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KR511_HUMAN             Reviewed;         156 AA.
AC   Q6L8G4;
DE   RecName: Full=Keratin-associated protein 5-11;
DE   AltName: Full=Keratin-associated protein 5.11;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.11;
GN   Name=KRTAP5-11; Synonyms=KAP5.11, KRTAP5.11;
//
ID   KR510_HUMAN             Reviewed;         202 AA.
AC   Q6L8G5; B9EHA4;
DE   RecName: Full=Keratin-associated protein 5-10;
DE   AltName: Full=Keratin-associated protein 5.10;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.10;
GN   Name=KRTAP5-10; Synonyms=KAP5.10, KRTAP5.10;
//
ID   KRA13_HUMAN             Reviewed;         177 AA.
AC   Q8IUG1; Q07628; Q8IUG0; Q9BYS2;
DE   RecName: Full=Keratin-associated protein 1-3;
DE   AltName: Full=Keratin-associated protein 1.8;
DE   AltName: Full=Keratin-associated protein 1.9;
GN   Name=KRTAP1-3;
GN   Synonyms=B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8;
DR   GO; GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB.
//
ID   KRA11_HUMAN             Reviewed;         177 AA.
AC   Q07627; A6NC32; Q96S60; Q96S67;
DE   RecName: Full=Keratin-associated protein 1-1;
DE   AltName: Full=High sulfur keratin-associated protein 1.1;
DE   AltName: Full=Keratin-associated protein 1.1;
DE   AltName: Full=Keratin-associated protein 1.6;
DE   AltName: Full=Keratin-associated protein 1.7;
GN   Name=KRTAP1-1; Synonyms=B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1;
//
ID   KRA14_HUMAN             Reviewed;         121 AA.
AC   P0C5Y4; A6NJ92;
DE   RecName: Full=Keratin-associated protein 1-4;
DE   AltName: Full=High sulfur keratin-associated protein 1.4;
DE   AltName: Full=Keratin-associated protein 1.4;
GN   Name=KRTAP1-4; Synonyms=KAP1.4, KRTAP1.4;
//
ID   KRA15_HUMAN             Reviewed;         174 AA.
AC   Q9BYS1; A6NJW6; A6NLZ6; B6ZDR1; Q52LP6;
DE   RecName: Full=Keratin-associated protein 1-5;
DE   AltName: Full=High sulfur keratin-associated protein 1.5;
DE   AltName: Full=Keratin-associated protein 1.5;
GN   Name=KRTAP1-5; Synonyms=KAP1.5, KRTAP1.5;
//
ID   KRA21_HUMAN             Reviewed;         128 AA.
AC   Q9BYU5;
DE   RecName: Full=Keratin-associated protein 2-1;
DE   AltName: Full=High sulfur keratin-associated protein 2.1;
DE   AltName: Full=Keratin-associated protein 2.1;
GN   Name=KRTAP2-1; Synonyms=KAP2.1, KRTAP2.1A, KRTAP2.1B;
//
ID   KRA22_HUMAN             Reviewed;         123 AA.
AC   Q9BYT5; A8MTN3; A8MXM4;
DE   RecName: Full=Keratin-associated protein 2-2;
DE   AltName: Full=High sulfur keratin-associated protein 2.2;
DE   AltName: Full=Keratin-associated protein 2.2;
GN   Name=KRTAP2-2; Synonyms=KAP2.2, KRTAP2.2;
//
ID   KRA23_HUMAN             Reviewed;         128 AA.
AC   P0C7H8;
DE   RecName: Full=Keratin-associated protein 2-3;
DE   AltName: Full=High sulfur keratin-associated protein 2.4;
DE   AltName: Full=Keratin-associated protein 2.3;
GN   Name=KRTAP2-3; Synonyms=KAP2.3, KRTAP2.3;
//
ID   KRA24_HUMAN             Reviewed;         128 AA.
AC   Q9BYR9; Q495J2;
DE   RecName: Full=Keratin-associated protein 2-4;
DE   AltName: Full=High sulfur keratin-associated protein 2.4;
DE   AltName: Full=Keratin-associated protein 2.4;
GN   Name=KRTAP2-4; Synonyms=KAP2.4, KRTAP2.4;
//
ID   KRA31_HUMAN             Reviewed;          98 AA.
AC   Q9BYR8; Q14DM4;
DE   RecName: Full=Keratin-associated protein 3-1;
DE   AltName: Full=High sulfur keratin-associated protein 3.1;
DE   AltName: Full=Keratin-associated protein 3.1;
GN   Name=KRTAP3-1; Synonyms=KAP3.1, KRTAP3.1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KRA32_HUMAN             Reviewed;          98 AA.
AC   Q9BYR7;
DE   RecName: Full=Keratin-associated protein 3-2;
DE   AltName: Full=High sulfur keratin-associated protein 3.2;
DE   AltName: Full=Keratin-associated protein 3.2;
GN   Name=KRTAP3-2; Synonyms=KAP3.2, KRTAP3.2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KRA33_HUMAN             Reviewed;          98 AA.
AC   Q9BYR6; Q52LP0; Q6NTD4;
DE   RecName: Full=Keratin-associated protein 3-3;
DE   AltName: Full=High sulfur keratin-associated protein 3.3;
DE   AltName: Full=Keratin-associated protein 3.3;
GN   Name=KRTAP3-3; Synonyms=KAP3.3, KRTAP3.3;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KRA42_HUMAN             Reviewed;         136 AA.
AC   Q9BYR5; A0JP64;
DE   RecName: Full=Keratin-associated protein 4-2;
DE   AltName: Full=Keratin-associated protein 4.2;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.2;
GN   Name=KRTAP4-2; Synonyms=KAP4.2, KRTAP4.2;
//
ID   KRA43_HUMAN             Reviewed;         195 AA.
AC   Q9BYR4;
DE   RecName: Full=Keratin-associated protein 4-3;
DE   AltName: Full=Keratin-associated protein 4.3;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.3;
GN   Name=KRTAP4-3; Synonyms=KAP4.3, KRTAP4.3;
//
ID   KRA41_HUMAN             Reviewed;         146 AA.
AC   Q9BYQ7; A8MWS7; Q3SYF2;
DE   RecName: Full=Keratin-associated protein 4-1;
DE   AltName: Full=Keratin-associated protein 4-10;
DE   AltName: Full=Keratin-associated protein 4.1;
DE   AltName: Full=Keratin-associated protein 4.10;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.10;
GN   Name=KRTAP4-1; Synonyms=KAP4.10, KRTAP4-10, KRTAP4.1, KRTAP4.10;
//
ID   KRA44_HUMAN             Reviewed;         166 AA.
AC   Q9BYR3; Q9BYU7;
DE   RecName: Full=Keratin-associated protein 4-4;
DE   AltName: Full=Keratin-associated protein 4-13;
DE   AltName: Full=Keratin-associated protein 4.13;
DE   AltName: Full=Keratin-associated protein 4.4;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.13;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.4;
GN   Name=KRTAP4-4;
GN   Synonyms=KAP4.13, KAP4.4, KRTAP4-13, KRTAP4.13, KRTAP4.4;
//
ID   KRA45_HUMAN             Reviewed;         181 AA.
AC   Q9BYR2;
DE   RecName: Full=Keratin-associated protein 4-5;
DE   AltName: Full=Keratin-associated protein 4.5;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.5;
GN   Name=KRTAP4-5; Synonyms=KAP4.5, KRTAP4.5;
//
ID   KRA46_HUMAN             Reviewed;         205 AA.
AC   Q9BYQ5; Q9BYR1;
DE   RecName: Full=Keratin-associated protein 4-6;
DE   AltName: Full=Keratin-associated protein 4-15;
DE   AltName: Full=Keratin-associated protein 4.15;
DE   AltName: Full=Keratin-associated protein 4.6;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.15;
GN   Name=KRTAP4-6; Synonyms=KAP4.15, KRTAP4-15, KRTAP4.15, KRTAP4.6;
//
ID   KRA47_HUMAN             Reviewed;         210 AA.
AC   Q9BYR0; A0AVM6; A8MQ08; A8MTL4;
DE   RecName: Full=Keratin-associated protein 4-7;
DE   AltName: Full=Keratin-associated protein 4.7;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.7;
GN   Name=KRTAP4-7; Synonyms=KAP4.7, KRTAP4.7;
//
ID   KRA48_HUMAN             Reviewed;         185 AA.
AC   Q9BYQ9; A8MSH3;
DE   RecName: Full=Keratin-associated protein 4-8;
DE   AltName: Full=Keratin-associated protein 4.8;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.8;
GN   Name=KRTAP4-8; Synonyms=KAP4.8, KRTAP4.8;
//
ID   KRA49_HUMAN             Reviewed;         210 AA.
AC   Q9BYQ8;
DE   RecName: Full=Keratin-associated protein 4-9;
DE   AltName: Full=Keratin-associated protein 4.9;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 4.9;
GN   Name=KRTAP4-9; Synonyms=KAP4.9, KRTAP4.9;
//
ID   KRA51_HUMAN             Reviewed;         278 AA.
AC   Q6L8H4;
DE   RecName: Full=Keratin-associated protein 5-1;
DE   AltName: Full=Keratin, cuticle, ultrahigh sulphur 1-like;
DE   AltName: Full=Keratin-associated protein 5.1;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.1;
GN   Name=KRTAP5-1; Synonyms=KAP5.1, KRN1L, KRTAP5.1;
//
ID   KRA52_HUMAN             Reviewed;         177 AA.
AC   Q701N4; A9JTZ1;
DE   RecName: Full=Keratin-associated protein 5-2;
DE   AltName: Full=Keratin-associated protein 5-8;
DE   AltName: Full=Keratin-associated protein 5.2;
DE   AltName: Full=Keratin-associated protein 5.8;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.2;
GN   Name=KRTAP5-2; Synonyms=KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8;
//
ID   KRA53_HUMAN             Reviewed;         238 AA.
AC   Q6L8H2; Q6PL44; Q701N3;
DE   RecName: Full=Keratin-associated protein 5-3;
DE   AltName: Full=Keratin-associated protein 5-9;
DE   AltName: Full=Keratin-associated protein 5.3;
DE   AltName: Full=Keratin-associated protein 5.9;
DE   AltName: Full=UHS KerB-like;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.3;
GN   Name=KRTAP5-3; Synonyms=KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9;
//
ID   KRA54_HUMAN             Reviewed;         288 AA.
AC   Q6L8H1;
DE   RecName: Full=Keratin-associated protein 5-4;
DE   AltName: Full=Keratin-associated protein 5.4;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.4;
GN   Name=KRTAP5-4; Synonyms=KAP5.4, KRTAP5.4;
//
ID   KRA55_HUMAN             Reviewed;         237 AA.
AC   Q701N2; A8MWN2;
DE   RecName: Full=Keratin-associated protein 5-5;
DE   AltName: Full=Keratin-associated protein 5-11;
DE   AltName: Full=Keratin-associated protein 5.11;
DE   AltName: Full=Keratin-associated protein 5.5;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.5;
GN   Name=KRTAP5-5;
GN   Synonyms=KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5;
//
ID   KRA56_HUMAN             Reviewed;         129 AA.
AC   Q6L8G9; A1L452;
DE   RecName: Full=Keratin-associated protein 5-6;
DE   AltName: Full=Keratin-associated protein 5.6;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.6;
GN   Name=KRTAP5-6; Synonyms=KAP5.6, KRTAP5.6;
//
ID   KRA57_HUMAN             Reviewed;         165 AA.
AC   Q6L8G8; B2RNM3; Q701N5;
DE   RecName: Full=Keratin-associated protein 5-7;
DE   AltName: Full=Keratin-associated protein 5-3;
DE   AltName: Full=Keratin-associated protein 5.3;
DE   AltName: Full=Keratin-associated protein 5.7;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.7;
GN   Name=KRTAP5-7; Synonyms=KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7;
//
ID   KRA58_HUMAN             Reviewed;         187 AA.
AC   O75690; Q6L8G7; Q6UTX6;
DE   RecName: Full=Keratin-associated protein 5-8;
DE   AltName: Full=Keratin, ultra high-sulfur matrix protein B;
DE   AltName: Full=Keratin-associated protein 5.8;
DE   AltName: Full=UHS keratin B;
DE            Short=UHS KerB;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.8;
GN   Name=KRTAP5-8; Synonyms=KAP5.8, KRTAP5.8, UHSKB;
DR   GO; GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB.
//
ID   KRA59_HUMAN             Reviewed;         169 AA.
AC   P26371; Q14564; Q3MIP8;
DE   RecName: Full=Keratin-associated protein 5-9;
DE   AltName: Full=Keratin, cuticle, ultrahigh sulfur 1;
DE   AltName: Full=Keratin, ultra high-sulfur matrix protein A;
DE   AltName: Full=Keratin-associated protein 5.9;
DE   AltName: Full=UHS keratin A;
DE            Short=UHS KerA;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 5.9;
GN   Name=KRTAP5-9; Synonyms=KAP5.9, KRN1, KRTAP5.9, UHSK1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   KRA61_HUMAN             Reviewed;          71 AA.
AC   Q3LI64;
DE   RecName: Full=Keratin-associated protein 6-1;
GN   Name=KRTAP6-1; Synonyms=C21orf103, KAP6.1;
//
ID   KRA62_HUMAN             Reviewed;          62 AA.
AC   Q3LI66;
DE   RecName: Full=Keratin-associated protein 6-2;
GN   Name=KRTAP6-2; Synonyms=KAP6.2;
//
ID   KRA63_HUMAN             Reviewed;         103 AA.
AC   Q3LI67; A4IF26;
DE   RecName: Full=Keratin-associated protein 6-3;
GN   Name=KRTAP6-3; Synonyms=KAP6.3;
//
ID   KRA71_HUMAN             Reviewed;          87 AA.
AC   Q8IUC3; Q3LI56;
DE   RecName: Full=Keratin-associated protein 7-1;
DE   AltName: Full=High tyrosine-glycine keratin-associated protein 7.1;
GN   Name=KRTAP7-1; Synonyms=KAP7.1, KRTAP7.1;
//
ID   KRA81_HUMAN             Reviewed;          63 AA.
AC   Q8IUC2; Q3LI57;
DE   RecName: Full=Keratin-associated protein 8-1;
DE   AltName: Full=High glycine-tyrosine keratin-associated protein 8.1;
GN   Name=KRTAP8-1; Synonyms=KAP8.1, KRTAP8.1;
//
ID   KRA91_HUMAN             Reviewed;         250 AA.
AC   A8MXZ3;
DE   RecName: Full=Keratin-associated protein 9-1;
GN   Name=KRTAP9-1; Synonyms=KAP9.1, KRTAP9.1;
//
ID   KRA92_HUMAN             Reviewed;         174 AA.
AC   Q9BYQ4; Q17RK8; Q2TB15;
DE   RecName: Full=Keratin-associated protein 9-2;
DE   AltName: Full=Keratin-associated protein 9.2;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 9.2;
GN   Name=KRTAP9-2; Synonyms=KAP9.2, KRTAP9.2;
//
ID   KRA93_HUMAN             Reviewed;         159 AA.
AC   Q9BYQ3;
DE   RecName: Full=Keratin-associated protein 9-3;
DE   AltName: Full=Keratin-associated protein 9.3;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 9.3;
GN   Name=KRTAP9-3; Synonyms=KAP9.3, KRTAP9.3;
//
ID   KRA94_HUMAN             Reviewed;         154 AA.
AC   Q9BYQ2; Q0VAE3;
DE   RecName: Full=Keratin-associated protein 9-4;
DE   AltName: Full=Keratin-associated protein 9.4;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 9.4;
GN   Name=KRTAP9-4; Synonyms=KAP9.4, KRTAP9.4;
//
ID   KRA96_HUMAN             Reviewed;         160 AA.
AC   A8MVA2;
DE   RecName: Full=Keratin-associated protein 9-6;
GN   Name=KRTAP9-6; Synonyms=KAP9.6, KRTAP9.6;
//
ID   KRA97_HUMAN             Reviewed;         169 AA.
AC   A8MTY7;
DE   RecName: Full=Keratin-associated protein 9-7;
GN   Name=KRTAP9-7; Synonyms=KAP9.7, KRTAP9.7;
//
ID   KRA98_HUMAN             Reviewed;         159 AA.
AC   Q9BYQ0;
DE   RecName: Full=Keratin-associated protein 9-8;
DE   AltName: Full=Keratin-associated protein 9.8;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 9.8;
GN   Name=KRTAP9-8; Synonyms=KAP9.8, KRTAP9.8;
//
ID   KRA99_HUMAN             Reviewed;         154 AA.
AC   Q9BYP9; B5MDD6; Q9BYQ1;
DE   RecName: Full=Keratin-associated protein 9-9;
DE   AltName: Full=Keratin-associated protein 9-5;
DE   AltName: Full=Keratin-associated protein 9.5;
DE   AltName: Full=Keratin-associated protein 9.9;
DE   AltName: Full=Ultrahigh sulfur keratin-associated protein 9.9;
GN   Name=KRTAP9-9; Synonyms=KAP9.5, KAP9.9, KRTAP9-5, KRTAP9.5, KRTAP9.9;
//
ID   KRBA1_HUMAN             Reviewed;        1030 AA.
AC   A5PL33; A7E2F5; E7ENE9; Q8N4X0; Q96JG5;
DE   RecName: Full=Protein KRBA1;
GN   Name=KRBA1; Synonyms=KIAA1862;
//
ID   KRBA2_HUMAN             Reviewed;         492 AA.
AC   Q6ZNG9; Q8IYY0;
DE   RecName: Full=KRAB-A domain-containing protein 2;
GN   Name=KRBA2;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   KRBX1_HUMAN             Reviewed;         128 AA.
AC   C9JBD0; B4DJE8;
DE   RecName: Full=KRAB domain-containing protein 1;
GN   Name=KRBOX1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   KRBX4_HUMAN             Reviewed;         171 AA.
AC   Q5JUW0; A8K0Y8; B3KU22; Q96EA3; Q9NXB1;
DE   RecName: Full=KRAB domain-containing protein 4;
DE   AltName: Full=KRAB box domain-containing protein 4;
GN   Name=KRBOX4; Synonyms=ZNF673;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   KRCC1_HUMAN             Reviewed;         259 AA.
AC   Q9NPI7; Q3B7J7;
DE   RecName: Full=Lysine-rich coiled-coil protein 1;
DE   AltName: Full=Cryptogenic hepatitis-binding protein 2;
GN   Name=KRCC1; Synonyms=CHBP2; ORFNames=BM-003, BM-044;
//
ID   KREM1_HUMAN             Reviewed;         473 AA.
AC   Q96MU8; B0QY46; B0QY47; B1AJR5; Q5TIB9; Q6P3X6; Q9BY70; Q9UGS5;
AC   Q9UGU1;
DE   RecName: Full=Kremen protein 1;
DE   AltName: Full=Dickkopf receptor;
DE   AltName: Full=Kringle domain-containing transmembrane protein 1;
DE   AltName: Full=Kringle-containing protein marking the eye and the nose;
DE   Flags: Precursor;
GN   Name=KREMEN1; Synonyms=KREMEN, KRM1;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007154; P:cell communication; TAS:UniProtKB.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KREM2_HUMAN             Reviewed;         462 AA.
AC   Q8NCW0; B4DXF6; I3L2S2; Q8N2J4; Q8NCW1; Q96GL8; Q9BTP9;
DE   RecName: Full=Kremen protein 2;
DE   AltName: Full=Dickkopf receptor 2;
DE   AltName: Full=Kringle domain-containing transmembrane protein 2;
DE   AltName: Full=Kringle-containing protein marking the eye and the nose;
DE   Flags: Precursor;
GN   Name=KREMEN2; Synonyms=KRM2;
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   KRI1_HUMAN              Reviewed;         703 AA.
AC   Q8N9T8; Q2M1R5; Q2M1R7; Q7L5J7; Q96G92; Q9BU50; Q9H6I1; Q9H978;
DE   RecName: Full=Protein KRI1 homolog;
GN   Name=KRI1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   KRIP1_HUMAN             Reviewed;         134 AA.
AC   Q107X0;
DE   RecName: Full=Putative protein KRIP1;
DE   AltName: Full=Kallikrein-related in prostate protein 1;
DE   AltName: Full=Kallikrein-related mRNA protein;
DE            Short=KARMA;
GN   Name=KLKP1; Synonyms=KLK31P;
//
ID   KRIT1_HUMAN             Reviewed;         736 AA.
AC   O00522; A6NNU0; O43894; Q506L6; Q6U276; Q75N19; Q9H180; Q9H264;
AC   Q9HAX5;
DE   RecName: Full=Krev interaction trapped protein 1;
DE            Short=Krev interaction trapped 1;
DE   AltName: Full=Cerebral cavernous malformations 1 protein;
GN   Name=KRIT1; Synonyms=CCM1;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   KRR1_HUMAN              Reviewed;         381 AA.
AC   Q13601; A0FIK6; A0JLP0; B2R989; E7EUQ0; Q8NEA8; Q8TC37; Q96AT5;
DE   RecName: Full=KRR1 small subunit processome component homolog;
DE   AltName: Full=HIV-1 Rev-binding protein 2;
DE   AltName: Full=KRR-R motif-containing protein 1;
DE   AltName: Full=Rev-interacting protein 1;
DE            Short=Rip-1;
GN   Name=KRR1; Synonyms=HRB2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   KRT34_HUMAN             Reviewed;         436 AA.
AC   O76011; Q8IUT8; Q8N4W2;
DE   RecName: Full=Keratin, type I cuticular Ha4;
DE   AltName: Full=Hair keratin, type I Ha4;
DE   AltName: Full=Keratin-34;
DE            Short=K34;
GN   Name=KRT34; Synonyms=HHA4, HKA4, KRTHA4;
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   KRT35_HUMAN             Reviewed;         455 AA.
AC   Q92764; O76012; Q92651;
DE   RecName: Full=Keratin, type I cuticular Ha5;
DE   AltName: Full=Hair keratin, type I Ha5;
DE   AltName: Full=Keratin-35;
DE            Short=K35;
GN   Name=KRT35; Synonyms=HHA5, HKA5, KRTHA5;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
//
ID   KRT36_HUMAN             Reviewed;         467 AA.
AC   O76013; Q86XG4;
DE   RecName: Full=Keratin, type I cuticular Ha6;
DE   AltName: Full=Hair keratin, type I Ha6;
DE   AltName: Full=Keratin-36;
DE            Short=K36;
GN   Name=KRT36; Synonyms=HHA6, HKA6, KRTHA6;
DR   GO; GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; IEA:Ensembl.
//
ID   KRT38_HUMAN             Reviewed;         456 AA.
AC   O76015; A2RRM5; Q6A164;
DE   RecName: Full=Keratin, type I cuticular Ha8;
DE   AltName: Full=Hair keratin, type I Ha8;
DE   AltName: Full=Keratin-38;
DE            Short=K38;
GN   Name=KRT38; Synonyms=HHA8, HKA8, KRTHA8;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
//
ID   KRT37_HUMAN             Reviewed;         449 AA.
AC   O76014;
DE   RecName: Full=Keratin, type I cuticular Ha7;
DE   AltName: Full=Hair keratin, type I Ha7;
DE   AltName: Full=Keratin-37;
DE            Short=K37;
GN   Name=KRT37; Synonyms=HHA7, HKA7, KRTHA7;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
//
ID   KRT81_HUMAN             Reviewed;         505 AA.
AC   Q14533; Q14846; Q16274; Q17R48; Q8WU52; Q9BR74;
DE   RecName: Full=Keratin, type II cuticular Hb1;
DE   AltName: Full=Hair keratin K2.9;
DE   AltName: Full=Keratin, hair, basic, 1;
DE   AltName: Full=Keratin-81;
DE            Short=K81;
DE   AltName: Full=Metastatic lymph node 137 gene protein;
DE            Short=MLN 137;
DE   AltName: Full=Type II hair keratin Hb1;
DE   AltName: Full=Type-II keratin Kb21;
DE   AltName: Full=ghHKb1;
DE            Short=ghHb1;
GN   Name=KRT81; Synonyms=KRTHB1, MLN137;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KRT82_HUMAN             Reviewed;         513 AA.
AC   Q9NSB4;
DE   RecName: Full=Keratin, type II cuticular Hb2;
DE   AltName: Full=Keratin-82;
DE            Short=K82;
DE   AltName: Full=Type II hair keratin Hb2;
DE   AltName: Full=Type-II keratin Kb22;
GN   Name=KRT82; Synonyms=KRTHB2;
DR   GO; GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB.
//
ID   KRT83_HUMAN             Reviewed;         493 AA.
AC   P78385; A1A4S9; B2RC21; Q6NT21; Q9NSB3;
DE   RecName: Full=Keratin, type II cuticular Hb3;
DE   AltName: Full=Hair keratin K2.10;
DE   AltName: Full=Keratin-83;
DE            Short=K83;
DE   AltName: Full=Type II hair keratin Hb3;
DE   AltName: Full=Type-II keratin Kb23;
GN   Name=KRT83; Synonyms=KRTHB3;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   KRT84_HUMAN             Reviewed;         600 AA.
AC   Q9NSB2; B2RA43; Q6ISB0; Q701L6;
DE   RecName: Full=Keratin, type II cuticular Hb4;
DE   AltName: Full=Keratin-84;
DE            Short=K84;
DE   AltName: Full=Type II hair keratin Hb4;
DE   AltName: Full=Type-II keratin Kb24;
GN   Name=KRT84; Synonyms=KRTHB4;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0030280; F:structural constituent of epidermis; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; NAS:UniProtKB.
DR   GO; GO:0035878; P:nail development; NAS:UniProtKB.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; IEA:Ensembl.
//
ID   KRT85_HUMAN             Reviewed;         507 AA.
AC   P78386; Q9NSB1;
DE   RecName: Full=Keratin, type II cuticular Hb5;
DE   AltName: Full=Hair keratin K2.12;
DE   AltName: Full=Keratin-85;
DE            Short=K85;
DE   AltName: Full=Type II hair keratin Hb5;
DE   AltName: Full=Type-II keratin Kb25;
GN   Name=KRT85; Synonyms=KRTHB5;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
//
ID   KRT86_HUMAN             Reviewed;         486 AA.
AC   O43790; P78387;
DE   RecName: Full=Keratin, type II cuticular Hb6;
DE   AltName: Full=Hair keratin K2.11;
DE   AltName: Full=Keratin-86;
DE            Short=K86;
DE   AltName: Full=Type II hair keratin Hb6;
DE   AltName: Full=Type-II keratin Kb26;
GN   Name=KRT86; Synonyms=KRTHB6;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KS6A1_HUMAN             Reviewed;         735 AA.
AC   Q15418; A6NGG4; A8K9K7; B2RDY8; B7Z5J0; Q5SVM5; Q5SVM8; Q5SVM9;
AC   Q96C05; Q9BQK2;
DE   RecName: Full=Ribosomal protein S6 kinase alpha-1;
DE            Short=S6K-alpha-1;
DE            EC=2.7.11.1;
DE   AltName: Full=90 kDa ribosomal protein S6 kinase 1;
DE            Short=p90-RSK 1;
DE            Short=p90RSK1;
DE            Short=p90S6K;
DE   AltName: Full=MAP kinase-activated protein kinase 1a;
DE            Short=MAPK-activated protein kinase 1a;
DE            Short=MAPKAP kinase 1a;
DE            Short=MAPKAPK-1a;
DE   AltName: Full=Ribosomal S6 kinase 1;
DE            Short=RSK-1;
GN   Name=RPS6KA1; Synonyms=MAPKAPK1A, RSK1;
DR   GuidetoPHARMACOLOGY; 1527; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:2000491; P:positive regulation of hepatic stellate cell activation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0043620; P:regulation of DNA-templated transcription in response to stress; TAS:UniProtKB.
DR   GO; GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   KS6A2_HUMAN             Reviewed;         733 AA.
AC   Q15349; B3KTK9; Q15419; Q59GJ3; Q5TI68; Q96J38; Q9UJN5;
DE   RecName: Full=Ribosomal protein S6 kinase alpha-2;
DE            Short=S6K-alpha-2;
DE            EC=2.7.11.1;
DE   AltName: Full=90 kDa ribosomal protein S6 kinase 2;
DE            Short=p90-RSK 2;
DE            Short=p90RSK2;
DE   AltName: Full=MAP kinase-activated protein kinase 1c;
DE            Short=MAPK-activated protein kinase 1c;
DE            Short=MAPKAP kinase 1c;
DE            Short=MAPKAPK-1c;
DE   AltName: Full=Ribosomal S6 kinase 3;
DE            Short=RSK-3;
DE   AltName: Full=pp90RSK3;
GN   Name=RPS6KA2; Synonyms=MAPKAPK1C, RSK3;
DR   GuidetoPHARMACOLOGY; 1529; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004711; F:ribosomal protein S6 kinase activity; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0002035; P:brain renin-angiotensin system; IEA:Ensembl.
DR   GO; GO:0010659; P:cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0071322; P:cellular response to carbohydrate stimulus; IEA:Ensembl.
DR   GO; GO:0060047; P:heart contraction; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045835; P:negative regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0070613; P:regulation of protein processing; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   KS6A3_HUMAN             Reviewed;         740 AA.
AC   P51812; B2R9V4; Q4VAP3; Q59H26; Q5JPK8; Q7Z3Z7;
DE   RecName: Full=Ribosomal protein S6 kinase alpha-3;
DE            Short=S6K-alpha-3;
DE            EC=2.7.11.1;
DE   AltName: Full=90 kDa ribosomal protein S6 kinase 3;
DE            Short=p90-RSK 3;
DE            Short=p90RSK3;
DE   AltName: Full=Insulin-stimulated protein kinase 1;
DE            Short=ISPK-1;
DE   AltName: Full=MAP kinase-activated protein kinase 1b;
DE            Short=MAPK-activated protein kinase 1b;
DE            Short=MAPKAP kinase 1b;
DE            Short=MAPKAPK-1b;
DE   AltName: Full=Ribosomal S6 kinase 2;
DE            Short=RSK-2;
DE   AltName: Full=pp90RSK2;
GN   Name=RPS6KA3; Synonyms=ISPK1, MAPKAPK1B, RSK2;
DR   GuidetoPHARMACOLOGY; 1528; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0043620; P:regulation of DNA-templated transcription in response to stress; TAS:UniProtKB.
DR   GO; GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   KS6A4_HUMAN             Reviewed;         772 AA.
AC   O75676; A8K7Z8; O75585; Q53ES8;
DE   RecName: Full=Ribosomal protein S6 kinase alpha-4;
DE            Short=S6K-alpha-4;
DE            EC=2.7.11.1;
DE   AltName: Full=90 kDa ribosomal protein S6 kinase 4;
DE   AltName: Full=Nuclear mitogen- and stress-activated protein kinase 2;
DE   AltName: Full=Ribosomal protein kinase B;
DE            Short=RSKB;
GN   Name=RPS6KA4; Synonyms=MSK2;
DR   GuidetoPHARMACOLOGY; 1524; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0048273; F:mitogen-activated protein kinase p38 binding; IGI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004711; F:ribosomal protein S6 kinase activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0043987; P:histone H3-S10 phosphorylation; IMP:UniProtKB.
DR   GO; GO:0043988; P:histone H3-S28 phosphorylation; IMP:UniProtKB.
DR   GO; GO:0016572; P:histone phosphorylation; TAS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0001818; P:negative regulation of cytokine production; TAS:UniProtKB.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.
DR   GO; GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   KS6A5_HUMAN             Reviewed;         802 AA.
AC   O75582; O95316; Q96AF7;
DE   RecName: Full=Ribosomal protein S6 kinase alpha-5;
DE            Short=S6K-alpha-5;
DE            EC=2.7.11.1;
DE   AltName: Full=90 kDa ribosomal protein S6 kinase 5;
DE   AltName: Full=Nuclear mitogen- and stress-activated protein kinase 1;
DE   AltName: Full=RSK-like protein kinase;
DE            Short=RSKL;
GN   Name=RPS6KA5; Synonyms=MSK1;
DR   GuidetoPHARMACOLOGY; 1523; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0043990; P:histone H2A-S1 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043987; P:histone H3-S10 phosphorylation; IMP:UniProtKB.
DR   GO; GO:0043988; P:histone H3-S28 phosphorylation; IMP:UniProtKB.
DR   GO; GO:0016572; P:histone phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001818; P:negative regulation of cytokine production; TAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.
DR   GO; GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   KS6A6_HUMAN             Reviewed;         745 AA.
AC   Q9UK32; B2R854; Q6FHX2; Q8WX28; Q9H4S6;
DE   RecName: Full=Ribosomal protein S6 kinase alpha-6;
DE            Short=S6K-alpha-6;
DE            EC=2.7.11.1;
DE   AltName: Full=90 kDa ribosomal protein S6 kinase 6;
DE            Short=p90-RSK 6;
DE            Short=p90RSK6;
DE   AltName: Full=Ribosomal S6 kinase 4;
DE            Short=RSK-4;
DE   AltName: Full=pp90RSK4;
GN   Name=RPS6KA6; Synonyms=RSK4;
DR   GuidetoPHARMACOLOGY; 1530; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.
DR   GO; GO:0045992; P:negative regulation of embryonic development; ISS:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:2000381; P:negative regulation of mesoderm development; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   KS6B1_HUMAN             Reviewed;         525 AA.
AC   P23443; B4DLT4; E7ESB8; Q7Z721;
DE   RecName: Full=Ribosomal protein S6 kinase beta-1;
DE            Short=S6K-beta-1;
DE            Short=S6K1;
DE            EC=2.7.11.1;
DE   AltName: Full=70 kDa ribosomal protein S6 kinase 1;
DE            Short=P70S6K1;
DE            Short=p70-S6K 1;
DE   AltName: Full=Ribosomal protein S6 kinase I;
DE   AltName: Full=Serine/threonine-protein kinase 14A;
DE   AltName: Full=p70 ribosomal S6 kinase alpha;
DE            Short=p70 S6 kinase alpha;
DE            Short=p70 S6K-alpha;
DE            Short=p70 S6KA;
GN   Name=RPS6KB1; Synonyms=STK14A;
DR   GuidetoPHARMACOLOGY; 1525; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004711; F:ribosomal protein S6 kinase activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0048633; P:positive regulation of skeletal muscle tissue growth; IEA:Ensembl.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0046324; P:regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0043201; P:response to leucine; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0014732; P:skeletal muscle atrophy; IEA:Ensembl.
DR   GO; GO:0003009; P:skeletal muscle contraction; IEA:Ensembl.
DR   GO; GO:0031929; P:TOR signaling; IDA:UniProtKB.
//
ID   KS6B2_HUMAN             Reviewed;         482 AA.
AC   Q9UBS0; B2RMZ9; O94809; Q9UEC1;
DE   RecName: Full=Ribosomal protein S6 kinase beta-2;
DE            Short=S6K-beta-2;
DE            Short=S6K2;
DE            EC=2.7.11.1;
DE   AltName: Full=70 kDa ribosomal protein S6 kinase 2;
DE            Short=P70S6K2;
DE            Short=p70-S6K 2;
DE   AltName: Full=S6 kinase-related kinase;
DE            Short=SRK;
DE   AltName: Full=Serine/threonine-protein kinase 14B;
DE   AltName: Full=p70 ribosomal S6 kinase beta;
DE            Short=S6K-beta;
DE            Short=p70 S6 kinase beta;
DE            Short=p70 S6K-beta;
DE            Short=p70 S6KB;
DE            Short=p70-beta;
GN   Name=RPS6KB2; Synonyms=STK14B;
DR   GuidetoPHARMACOLOGY; 1526; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004711; F:ribosomal protein S6 kinase activity; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   KS6C1_HUMAN             Reviewed;        1066 AA.
AC   Q96S38; B1APS8; B3KVM4; D3DTA4; Q8TDD3; Q9NSF4; Q9UL66;
DE   RecName: Full=Ribosomal protein S6 kinase delta-1;
DE            Short=S6K-delta-1;
DE            EC=2.7.11.1;
DE   AltName: Full=52 kDa ribosomal protein S6 kinase;
DE   AltName: Full=Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein;
DE   AltName: Full=SPHK1-binding protein;
GN   Name=RPS6KC1; Synonyms=RPK118;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   KSR1_HUMAN              Reviewed;         921 AA.
AC   Q8IVT5; Q13476;
DE   RecName: Full=Kinase suppressor of Ras 1;
GN   Name=KSR1; Synonyms=KSR;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
//
ID   KSR2_HUMAN              Reviewed;         950 AA.
AC   Q6VAB6; A0PJT2; Q3B828; Q8N775;
DE   RecName: Full=Kinase suppressor of Ras 2;
DE            Short=hKSR2;
DE            EC=2.7.11.1;
GN   Name=KSR2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
//
ID   KSYK_HUMAN              Reviewed;         635 AA.
AC   P43405;
DE   RecName: Full=Tyrosine-protein kinase SYK;
DE            EC=2.7.10.2;
DE   AltName: Full=Spleen tyrosine kinase;
DE   AltName: Full=p72-Syk;
GN   Name=SYK;
DR   GuidetoPHARMACOLOGY; 2230; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; EXP:Reactome.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:Ensembl.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0002250; P:adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043366; P:beta selection; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048514; P:blood vessel morphogenesis; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071226; P:cellular response to molecule of fungal origin; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; ISS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0002366; P:leukocyte activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001945; P:lymph vessel development; ISS:UniProtKB.
DR   GO; GO:0002281; P:macrophage activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0002283; P:neutrophil activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; ISS:UniProtKB.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0045425; P:positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045401; P:positive regulation of interleukin-3 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043306; P:positive regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0090237; P:regulation of arachidonic acid secretion; ISS:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0043313; P:regulation of neutrophil degranulation; ISS:UniProtKB.
DR   GO; GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.
DR   GO; GO:0010543; P:regulation of platelet activation; ISS:UniProtKB.
DR   GO; GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0032928; P:regulation of superoxide anion generation; ISS:UniProtKB.
DR   GO; GO:0002554; P:serotonin secretion by platelet; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   KT222_HUMAN             Reviewed;         295 AA.
AC   Q8N1A0; Q7Z368;
DE   RecName: Full=Keratin-like protein KRT222;
DE   AltName: Full=Keratin-222;
DE   AltName: Full=Keratin-222 pseudogene;
GN   Name=KRT222; Synonyms=KA21, KRT222P;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KT33A_HUMAN             Reviewed;         404 AA.
AC   O76009; B2RA87; Q6NTB9; Q6ZZB9;
DE   RecName: Full=Keratin, type I cuticular Ha3-I;
DE   AltName: Full=Hair keratin, type I Ha3-I;
DE   AltName: Full=Keratin-33A;
DE            Short=K33A;
GN   Name=KRT33A; Synonyms=HHA3-I, HKA3A, KRTHA3A;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KT3K_HUMAN              Reviewed;         309 AA.
AC   Q9HA64; Q969F4; Q9H0U7;
DE   RecName: Full=Ketosamine-3-kinase;
DE            EC=2.7.1.-;
DE   AltName: Full=Fructosamine-3-kinase-related protein;
DE            Short=FN3K-RP;
DE            Short=FN3K-related protein;
GN   Name=FN3KRP;
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
//
ID   KT33B_HUMAN             Reviewed;         404 AA.
AC   Q14525; O76010;
DE   RecName: Full=Keratin, type I cuticular Ha3-II;
DE   AltName: Full=Hair keratin, type I Ha3-II;
DE   AltName: Full=Keratin-33B;
DE            Short=K33B;
GN   Name=KRT33B; Synonyms=HHA3-II, HKA3B, KRTHA3B;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   KTAP2_HUMAN             Reviewed;         136 AA.
AC   Q8N6L1; B2R4Q1; Q6PG45; Q86XW2; Q8IWS4;
DE   RecName: Full=Keratinocyte-associated protein 2;
DE            Short=KCP-2;
GN   Name=KRTCAP2; Synonyms=KCP2;
//
ID   KTDAP_HUMAN             Reviewed;          99 AA.
AC   P60985; A1L4D7;
DE   RecName: Full=Keratinocyte differentiation-associated protein;
DE   Flags: Precursor;
GN   Name=KRTDAP; Synonyms=KDAP; ORFNames=UNQ467/PRO826;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   KTAS1_HUMAN             Reviewed;          53 AA.
AC   Q86SY8;
DE   RecName: Full=Putative uncharacterized protein KTN1-AS1;
DE   AltName: Full=KTN1 antisense RNA 1;
DE   AltName: Full=KTN1 antisense gene protein 1;
GN   Name=KTN1-AS1; Synonyms=C14orf33;
//
ID   KTBL1_HUMAN             Reviewed;         304 AA.
AC   Q9H079; A8KAF6; Q2TAC0; Q9H670;
DE   RecName: Full=KATNB1-like protein 1;
DE   AltName: Full=Katanin p80 subunit B-like 1;
GN   Name=KATNBL1; Synonyms=C15orf29;
//
ID   KTHY_HUMAN              Reviewed;         212 AA.
AC   P23919; B7ZW70; Q6FGX1; Q9BUX4;
DE   RecName: Full=Thymidylate kinase;
DE            EC=2.7.4.9;
DE   AltName: Full=dTMP kinase;
GN   Name=DTYMK; Synonyms=CDC8, TMPK, TYMK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050145; F:nucleoside phosphate kinase activity; EXP:Reactome.
DR   GO; GO:0004798; F:thymidylate kinase activity; IDA:MGI.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0006233; P:dTDP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046940; P:nucleoside monophosphate phosphorylation; EXP:GOC.
DR   GO; GO:0046939; P:nucleotide phosphorylation; IDA:GOC.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   KTI12_HUMAN             Reviewed;         354 AA.
AC   Q96EK9;
DE   RecName: Full=Protein KTI12 homolog;
GN   Name=KTI12; ORFNames=SBBI81;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   KTN1_HUMAN              Reviewed;        1357 AA.
AC   Q86UP2; B4DZ88; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86W57;
DE   RecName: Full=Kinectin;
DE   AltName: Full=CG-1 antigen;
DE   AltName: Full=Kinesin receptor;
GN   Name=KTN1; Synonyms=CG1, KIAA0004;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; NAS:ProtInc.
//
ID   KTNA1_HUMAN             Reviewed;         491 AA.
AC   O75449; E1P5A3; Q5TFA8; Q5TFA9; Q86VN2; Q9NU52;
DE   RecName: Full=Katanin p60 ATPase-containing subunit A1;
DE            Short=Katanin p60 subunit A1;
DE            EC=3.6.4.3;
DE   AltName: Full=p60 katanin;
GN   Name=KATNA1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0008568; F:microtubule-severing ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:Ensembl.
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0051013; P:microtubule severing; IEA:UniProtKB-HAMAP.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051329; P:mitotic interphase; IMP:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
//
ID   KTNB1_HUMAN             Reviewed;         655 AA.
AC   Q9BVA0; A6NCG6; O60620;
DE   RecName: Full=Katanin p80 WD40 repeat-containing subunit B1;
DE            Short=Katanin p80 subunit B1;
DE   AltName: Full=p80 katanin;
GN   Name=KATNB1;
DR   GO; GO:0008017; F:microtubule binding; NAS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0051013; P:microtubule severing; IEA:UniProtKB-HAMAP.
DR   GO; GO:0007079; P:mitotic chromosome movement towards spindle pole; IEA:UniProtKB-HAMAP.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0031117; P:positive regulation of microtubule depolymerization; IMP:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; NAS:UniProtKB.
//
ID   KTU_HUMAN               Reviewed;         837 AA.
AC   Q9NVR5; B9WS54; C0JAP7; Q86TR1; Q86TY8; Q969Z5;
DE   RecName: Full=Protein kintoun;
DE   AltName: Full=Dynein assembly factor 2, axonemal;
GN   Name=DNAAF2; Synonyms=C14orf104, KTU;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IMP:UniProtKB.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IMP:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   KV102_HUMAN             Reviewed;         108 AA.
AC   P01594;
DE   RecName: Full=Ig kappa chain V-I region AU;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV101_HUMAN             Reviewed;         108 AA.
AC   P01593;
DE   RecName: Full=Ig kappa chain V-I region AG;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV103_HUMAN             Reviewed;         108 AA.
AC   P01595;
DE   RecName: Full=Ig kappa chain V-I region Bi;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV104_HUMAN             Reviewed;         107 AA.
AC   P01596;
DE   RecName: Full=Ig kappa chain V-I region CAR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV105_HUMAN             Reviewed;         108 AA.
AC   P01597;
DE   RecName: Full=Ig kappa chain V-I region DEE;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV107_HUMAN             Reviewed;         108 AA.
AC   P01599;
DE   RecName: Full=Ig kappa chain V-I region Gal;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV106_HUMAN             Reviewed;         108 AA.
AC   P01598;
DE   RecName: Full=Ig kappa chain V-I region EU;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV108_HUMAN             Reviewed;         108 AA.
AC   P01600;
DE   RecName: Full=Ig kappa chain V-I region Hau;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV109_HUMAN             Reviewed;         117 AA.
AC   P01601;
DE   RecName: Full=Ig kappa chain V-I region HK101;
DE   Flags: Precursor; Fragment;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV110_HUMAN             Reviewed;         117 AA.
AC   P01602;
DE   RecName: Full=Ig kappa chain V-I region HK102;
DE   Flags: Precursor; Fragment;
GN   Name=IGKV1-5;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV112_HUMAN             Reviewed;         108 AA.
AC   P01604;
DE   RecName: Full=Ig kappa chain V-I region Kue;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV111_HUMAN             Reviewed;         108 AA.
AC   P01603;
DE   RecName: Full=Ig kappa chain V-I region Ka;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV113_HUMAN             Reviewed;         108 AA.
AC   P01605;
DE   RecName: Full=Ig kappa chain V-I region Lay;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV114_HUMAN             Reviewed;         108 AA.
AC   P01606;
DE   RecName: Full=Ig kappa chain V-I region OU;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV115_HUMAN             Reviewed;         108 AA.
AC   P01607;
DE   RecName: Full=Ig kappa chain V-I region Rei;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV116_HUMAN             Reviewed;         108 AA.
AC   P01608;
DE   RecName: Full=Ig kappa chain V-I region Roy;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV118_HUMAN             Reviewed;         108 AA.
AC   P01610;
DE   RecName: Full=Ig kappa chain V-I region WEA;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV117_HUMAN             Reviewed;         108 AA.
AC   P01609;
DE   RecName: Full=Ig kappa chain V-I region Scw;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV119_HUMAN             Reviewed;         108 AA.
AC   P01611;
DE   RecName: Full=Ig kappa chain V-I region Wes;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV122_HUMAN             Reviewed;         108 AA.
AC   P04430;
DE   RecName: Full=Ig kappa chain V-I region BAN;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV123_HUMAN             Reviewed;         129 AA.
AC   P04431;
DE   RecName: Full=Ig kappa chain V-I region Walker;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV124_HUMAN             Reviewed;         129 AA.
AC   P04432;
DE   RecName: Full=Ig kappa chain V-I region Daudi;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV120_HUMAN             Reviewed;         109 AA.
AC   P01612;
DE   RecName: Full=Ig kappa chain V-I region Mev;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV125_HUMAN             Reviewed;         108 AA.
AC   P80362;
DE   RecName: Full=Ig kappa chain V-I region WAT;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV121_HUMAN             Reviewed;         112 AA.
AC   P01613;
DE   RecName: Full=Ig kappa chain V-I region Ni;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV202_HUMAN             Reviewed;         113 AA.
AC   P01615;
DE   RecName: Full=Ig kappa chain V-II region FR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV203_HUMAN             Reviewed;         112 AA.
AC   P01616;
DE   RecName: Full=Ig kappa chain V-II region MIL;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV205_HUMAN             Reviewed;         117 AA.
AC   P06309;
DE   RecName: Full=Ig kappa chain V-II region GM607;
DE   Flags: Precursor; Fragment;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV206_HUMAN             Reviewed;         133 AA.
AC   P06310;
DE   RecName: Full=Ig kappa chain V-II region RPMI 6410;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV201_HUMAN             Reviewed;         115 AA.
AC   P01614;
DE   RecName: Full=Ig kappa chain V-II region Cum;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV204_HUMAN             Reviewed;         113 AA.
AC   P01617;
DE   RecName: Full=Ig kappa chain V-II region TEW;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV306_HUMAN             Reviewed;         109 AA.
AC   P01624;
DE   RecName: Full=Ig kappa chain V-III region POM;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV305_HUMAN             Reviewed;         109 AA.
AC   P01623;
DE   RecName: Full=Ig kappa chain V-III region WOL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV302_HUMAN             Reviewed;         109 AA.
AC   P01620;
DE   RecName: Full=Ig kappa chain V-III region SIE;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV309_HUMAN             Reviewed;         115 AA.
AC   P04433;
DE   RecName: Full=Ig kappa chain V-III region VG;
DE   Flags: Precursor; Fragment;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV310_HUMAN             Reviewed;         116 AA.
AC   P04434;
DE   RecName: Full=Ig kappa chain V-III region VH;
DE   Flags: Precursor; Fragment;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV301_HUMAN             Reviewed;         108 AA.
AC   P01619;
DE   RecName: Full=Ig kappa chain V-III region B6;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV303_HUMAN             Reviewed;         100 AA.
AC   P01621;
DE   RecName: Full=Ig kappa chain V-III region NG9;
DE   Flags: Precursor; Fragment;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV312_HUMAN             Reviewed;         129 AA.
AC   P18135;
DE   RecName: Full=Ig kappa chain V-III region HAH;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV307_HUMAN             Reviewed;         109 AA.
AC   P04206;
DE   RecName: Full=Ig kappa chain V-III region GOL;
DE   AltName: Full=Rheumatoid factor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV304_HUMAN             Reviewed;         109 AA.
AC   P01622;
DE   RecName: Full=Ig kappa chain V-III region Ti;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV311_HUMAN             Reviewed;         128 AA.
AC   P06311;
DE   RecName: Full=Ig kappa chain V-III region IARC/BL41;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV313_HUMAN             Reviewed;         129 AA.
AC   P18136;
DE   RecName: Full=Ig kappa chain V-III region HIC;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0003094; P:glomerular filtration; IMP:UniProt.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV308_HUMAN             Reviewed;         129 AA.
AC   P04207;
DE   RecName: Full=Ig kappa chain V-III region CLL;
DE   AltName: Full=Rheumatoid factor;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV402_HUMAN             Reviewed;         114 AA.
AC   P01625;
DE   RecName: Full=Ig kappa chain V-IV region Len;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV403_HUMAN             Reviewed;         133 AA.
AC   P06313;
DE   RecName: Full=Ig kappa chain V-IV region JI;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV404_HUMAN             Reviewed;         134 AA.
AC   P06314;
DE   RecName: Full=Ig kappa chain V-IV region B17;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV405_HUMAN             Reviewed;         109 AA.
AC   P83593;
DE   RecName: Full=Ig kappa chain V-IV region STH;
DE   Flags: Fragment;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV501_HUMAN             Reviewed;         115 AA.
AC   P06315;
DE   RecName: Full=Ig kappa chain V region EV15;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KV401_HUMAN             Reviewed;         121 AA.
AC   P06312;
DE   RecName: Full=Ig kappa chain V-IV region;
DE   Flags: Precursor; Fragment;
GN   Name=IGKV4-1;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   KXDL1_HUMAN             Reviewed;         176 AA.
AC   Q9BQD3; O76098;
DE   RecName: Full=KxDL motif-containing protein 1;
GN   Name=KXD1; Synonyms=C19orf50;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   KYNU_HUMAN              Reviewed;         465 AA.
AC   Q16719; B2RCZ5; D3DP79; Q6I9T2; Q9BVW3;
DE   RecName: Full=Kynureninase;
DE            EC=3.7.1.3;
DE   AltName: Full=L-kynurenine hydrolase;
GN   Name=KYNU;
DR   GO; GO:0030429; F:kynureninase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034354; P:'de novo' NAD biosynthetic process from tryptophan; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043420; P:anthranilate metabolic process; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0097053; P:L-kynurenine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019805; P:quinolinate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0034516; P:response to vitamin B6; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; IMP:UniProtKB.
DR   GO; GO:0019442; P:tryptophan catabolic process to acetyl-CoA; IEA:Ensembl.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:Ensembl.
//
ID   KY_HUMAN                Reviewed;         561 AA.
AC   Q8NBH2; B7Z1S4; Q6ZT15;
DE   RecName: Full=Kyphoscoliosis peptidase;
DE            EC=3.4.-.-;
GN   Name=KY;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
//
ID   L10K_HUMAN              Reviewed;          99 AA.
AC   Q9UNZ5; B2R4J9;
DE   RecName: Full=Leydig cell tumor 10 kDa protein homolog;
GN   Name=C19orf53; ORFNames=HSPC023;
//
ID   L12R1_HUMAN             Reviewed;         196 AA.
AC   Q969J3; Q96QS5;
DE   RecName: Full=Loss of heterozygosity 12 chromosomal region 1 protein;
GN   Name=LOH12CR1;
//
ID   L1CAM_HUMAN             Reviewed;        1257 AA.
AC   P32004; A0AV65; A4ZYW4; B2RMU7; G3XAF4; Q8TA87;
DE   RecName: Full=Neural cell adhesion molecule L1;
DE            Short=N-CAM-L1;
DE            Short=NCAM-L1;
DE   AltName: CD_antigen=CD171;
DE   Flags: Precursor;
GN   Name=L1CAM; Synonyms=CAML1, MIC5;
DR   GO; GO:0033691; F:sialic acid binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0033631; P:cell-cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:BHF-UCL.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IEA:Ensembl.
//
ID   L2GL1_HUMAN             Reviewed;        1064 AA.
AC   Q15334; A7MBM7; O00188; Q58F11; Q86UK6;
DE   RecName: Full=Lethal(2) giant larvae protein homolog 1;
DE            Short=LLGL;
DE   AltName: Full=DLG4;
DE   AltName: Full=Hugl-1;
DE   AltName: Full=Human homolog to the D-lgl gene protein;
GN   Name=LLGL1; Synonyms=DLG4, HUGL, HUGL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; ISS:UniProtKB.
DR   GO; GO:0035090; P:maintenance of apical/basal cell polarity; IEA:Ensembl.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; ISS:GOC.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
//
ID   L2GL2_HUMAN             Reviewed;        1020 AA.
AC   Q6P1M3; Q14521; Q9BR62;
DE   RecName: Full=Lethal(2) giant larvae protein homolog 2;
DE   AltName: Full=HGL;
GN   Name=LLGL2;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0032878; P:regulation of establishment or maintenance of cell polarity; IDA:UniProtKB.
//
ID   L2HDH_HUMAN             Reviewed;         463 AA.
AC   Q9H9P8; Q9BRR1;
DE   RecName: Full=L-2-hydroxyglutarate dehydrogenase, mitochondrial;
DE            EC=1.1.99.2;
DE   AltName: Full=Duranin;
DE   Flags: Precursor;
GN   Name=L2HGDH; Synonyms=C14orf160;
DR   GO; GO:0047545; F:2-hydroxyglutarate dehydrogenase activity; IDA:HGNC.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; IDA:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   L37A1_HUMAN             Reviewed;        1700 AA.
AC   A6NMS7; Q68DY2; Q8IWC7;
DE   RecName: Full=Leucine-rich repeat-containing protein 37A;
DE   Flags: Precursor;
GN   Name=LRRC37A; Synonyms=LRRC37A1;
//
ID   L37A2_HUMAN             Reviewed;        1700 AA.
AC   A6NM11; B7ZMC3;
DE   RecName: Full=Leucine-rich repeat-containing protein 37A2;
DE   Flags: Precursor;
GN   Name=LRRC37A2;
//
ID   L37A3_HUMAN             Reviewed;        1634 AA.
AC   O60309; Q49A01; Q49A80; Q8NB33;
DE   RecName: Full=Leucine-rich repeat-containing protein 37A3;
DE   Flags: Precursor;
GN   Name=LRRC37A3; Synonyms=KIAA0563;
//
ID   L37A5_HUMAN             Reviewed;         106 AA.
AC   Q49AS3; Q5JVP0;
DE   RecName: Full=Putative protein LRRC37A5P;
DE   AltName: Full=Leucine-rich repeat-containing 37 member A5 pseudogene;
GN   Name=LRRC37A5P; Synonyms=C9orf29;
//
ID   L3R2A_HUMAN             Reviewed;          94 AA.
AC   Q9Y6C7;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00312;
DE   AltName: Full=Loss of heterozygosity 3 chromosomal region 2 gene A protein;
GN   Name=LINC00312; Synonyms=LOH3CR2A, NCRNA00312; ORFNames=NAG7;
//
ID   LAAT1_HUMAN             Reviewed;         291 AA.
AC   Q6ZP29; B3KWQ5; Q6ZMJ3; Q6ZP27; Q9NXC7;
DE   RecName: Full=Lysosomal amino acid transporter 1 homolog;
DE   AltName: Full=PQ-loop repeat-containing protein 2;
GN   Name=PQLC2;
DR   GO; GO:0015181; F:arginine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015326; F:cationic amino acid transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015189; F:L-lysine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0080144; P:amino acid homeostasis; IDA:UniProtKB.
DR   GO; GO:0003333; P:amino acid transmembrane transport; ISS:GOC.
DR   GO; GO:0015809; P:arginine transport; IDA:UniProtKB.
DR   GO; GO:0015819; P:lysine transport; IDA:UniProtKB.
//
ID   LAC1_HUMAN              Reviewed;         106 AA.
AC   P0CG04; A0M8Q4; P01842; P80423;
DE   RecName: Full=Ig lambda-1 chain C regions;
GN   Name=IGLC1;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LAC2_HUMAN              Reviewed;         106 AA.
AC   P0CG05; A0M8Q4; P80423;
DE   RecName: Full=Ig lambda-2 chain C regions;
GN   Name=IGLC2;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LAC3_HUMAN              Reviewed;         106 AA.
AC   P0CG06; A0M8Q4; P80423;
DE   RecName: Full=Ig lambda-3 chain C regions;
GN   Name=IGLC3;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LAC6_HUMAN              Reviewed;         106 AA.
AC   P0CF74;
DE   RecName: Full=Ig lambda-6 chain C region;
GN   Name=IGLC6;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LAC7_HUMAN              Reviewed;         106 AA.
AC   A0M8Q6;
DE   RecName: Full=Ig lambda-7 chain C region;
GN   Name=IGLC7;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LACB2_HUMAN             Reviewed;         288 AA.
AC   Q53H82; Q9Y392;
DE   RecName: Full=Beta-lactamase-like protein 2;
DE            EC=3.-.-.-;
GN   Name=LACTB2; ORFNames=CGI-83;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   LACC1_HUMAN             Reviewed;         430 AA.
AC   Q8IV20; A2A3Z6; Q8N8X5;
DE   RecName: Full=Laccase domain-containing protein 1;
GN   Name=LACC1; Synonyms=C13orf31;
//
ID   LACE1_HUMAN             Reviewed;         481 AA.
AC   Q8WV93; Q8N6A3;
DE   RecName: Full=Lactation elevated protein 1;
DE   AltName: Full=Protein AFG1 homolog;
GN   Name=LACE1; Synonyms=AFG1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   LACRT_HUMAN             Reviewed;         138 AA.
AC   Q9GZZ8;
DE   RecName: Full=Extracellular glycoprotein lacritin;
DE   Flags: Precursor;
GN   Name=LACRT;
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0001968; F:fibronectin binding; IDA:UniProtKB.
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0043237; F:laminin-1 binding; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0033173; P:calcineurin-NFAT signaling cascade; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051533; P:positive regulation of NFAT protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0051047; P:positive regulation of secretion; IDA:UniProtKB.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IDA:UniProtKB.
DR   GO; GO:0070075; P:tear secretion; NAS:UniProtKB.
//
ID   LACTB_HUMAN             Reviewed;         547 AA.
AC   P83111; P83096;
DE   RecName: Full=Serine beta-lactamase-like protein LACTB, mitochondrial;
DE            EC=3.4.-.-;
DE   Flags: Precursor;
GN   Name=LACTB; Synonyms=MRPL56; ORFNames=UNQ843/PRO1781;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   LAD1_HUMAN              Reviewed;         517 AA.
AC   O00515; O95614; Q96GD8;
DE   RecName: Full=Ladinin-1;
DE            Short=Lad-1;
DE   AltName: Full=Linear IgA disease antigen;
DE            Short=LADA;
GN   Name=LAD1; Synonyms=LAD;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
//
ID   LAG3_HUMAN              Reviewed;         525 AA.
AC   P18627; A8K7T9;
DE   RecName: Full=Lymphocyte activation gene 3 protein;
DE            Short=LAG-3;
DE   AltName: Full=Protein FDC;
DE   AltName: CD_antigen=CD223;
DE   Flags: Precursor;
GN   Name=LAG3; Synonyms=FDC;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0042289; F:MHC class II protein binding; IDA:MGI.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
//
ID   LAGE3_HUMAN             Reviewed;         143 AA.
AC   Q14657; Q5HY39; Q8IZ78;
DE   RecName: Full=EKC/KEOPS complex subunit LAGE3;
DE   AltName: Full=L antigen family member 3;
DE   AltName: Full=Protein ESO-3;
DE   AltName: Full=Protein ITBA2;
GN   Name=LAGE3; Synonyms=DXS9879E, ESO3, ITBA2;
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   LAIR1_HUMAN             Reviewed;         287 AA.
AC   Q6GTX8;
DE   RecName: Full=Leukocyte-associated immunoglobulin-like receptor 1;
DE            Short=LAIR-1;
DE            Short=hLAIR1;
DE   AltName: CD_antigen=CD305;
DE   Flags: Precursor;
GN   Name=LAIR1; Synonyms=CD305;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   LAIR2_HUMAN             Reviewed;         152 AA.
AC   Q6ISS4; Q6PEZ4;
DE   RecName: Full=Leukocyte-associated immunoglobulin-like receptor 2;
DE            Short=LAIR-2;
DE   AltName: CD_antigen=CD306;
DE   Flags: Precursor;
GN   Name=LAIR2; Synonyms=CD306;
//
ID   LALBA_HUMAN             Reviewed;         142 AA.
AC   P00709; Q6FGX0; Q9UDK4;
DE   RecName: Full=Alpha-lactalbumin;
DE   AltName: Full=Lactose synthase B protein;
DE   AltName: Full=Lysozyme-like protein 7;
DE   Flags: Precursor;
GN   Name=LALBA; Synonyms=LYZL7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004461; F:lactose synthase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:ProtInc.
DR   GO; GO:0005989; P:lactose biosynthetic process; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LAMA1_HUMAN             Reviewed;        3075 AA.
AC   P25391;
DE   RecName: Full=Laminin subunit alpha-1;
DE   AltName: Full=Laminin A chain;
DE   AltName: Full=Laminin-1 subunit alpha;
DE   AltName: Full=Laminin-3 subunit alpha;
DE   AltName: Full=S-laminin subunit alpha;
DE            Short=S-LAM alpha;
DE   Flags: Precursor;
GN   Name=LAMA1; Synonyms=LAMA;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; ISS:UniProtKB.
DR   GO; GO:0043208; F:glycosphingolipid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0045198; P:establishment of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR   GO; GO:0061304; P:retinal blood vessel morphogenesis; IEA:Ensembl.
//
ID   LAMA2_HUMAN             Reviewed;        3122 AA.
AC   P24043; Q14736; Q5VUM2; Q93022;
DE   RecName: Full=Laminin subunit alpha-2;
DE   AltName: Full=Laminin M chain;
DE   AltName: Full=Laminin-12 subunit alpha;
DE   AltName: Full=Laminin-2 subunit alpha;
DE   AltName: Full=Laminin-4 subunit alpha;
DE   AltName: Full=Merosin heavy chain;
DE   Flags: Precursor;
GN   Name=LAMA2; Synonyms=LAMM;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
//
ID   LAMA3_HUMAN             Reviewed;        3333 AA.
AC   Q16787; Q13679; Q13680; Q6VU67; Q6VU68; Q6VU69; Q76E14; Q96TG0;
DE   RecName: Full=Laminin subunit alpha-3;
DE   AltName: Full=Epiligrin 170 kDa subunit;
DE            Short=E170;
DE   AltName: Full=Epiligrin subunit alpha;
DE   AltName: Full=Kalinin subunit alpha;
DE   AltName: Full=Laminin-5 subunit alpha;
DE   AltName: Full=Laminin-6 subunit alpha;
DE   AltName: Full=Laminin-7 subunit alpha;
DE   AltName: Full=Nicein subunit alpha;
DE   Flags: Precursor;
GN   Name=LAMA3; Synonyms=LAMNA;
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
//
ID   LAMA4_HUMAN             Reviewed;        1823 AA.
AC   Q16363; Q14731; Q14735; Q15335; Q4LE44; Q5SZG8; Q9BTB8; Q9UE18;
AC   Q9UJN9;
DE   RecName: Full=Laminin subunit alpha-4;
DE   AltName: Full=Laminin-14 subunit alpha;
DE   AltName: Full=Laminin-8 subunit alpha;
DE   AltName: Full=Laminin-9 subunit alpha;
DE   Flags: Precursor;
GN   Name=LAMA4;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
//
ID   LAMA5_HUMAN             Reviewed;        3695 AA.
AC   O15230; Q8TDF8; Q8WZA7; Q9H1P1;
DE   RecName: Full=Laminin subunit alpha-5;
DE   AltName: Full=Laminin-10 subunit alpha;
DE   AltName: Full=Laminin-11 subunit alpha;
DE   AltName: Full=Laminin-15 subunit alpha;
DE   Flags: Precursor;
GN   Name=LAMA5; Synonyms=KIAA0533, KIAA1907;
DR   GO; GO:0005178; F:integrin binding; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IC:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0008037; P:cell recognition; NAS:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0045446; P:endothelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0001738; P:morphogenesis of a polarized epithelium; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:InterPro.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:InterPro.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
//
ID   LAMB1_HUMAN             Reviewed;        1786 AA.
AC   P07942; Q14D91;
DE   RecName: Full=Laminin subunit beta-1;
DE   AltName: Full=Laminin B1 chain;
DE   AltName: Full=Laminin-1 subunit beta;
DE   AltName: Full=Laminin-10 subunit beta;
DE   AltName: Full=Laminin-12 subunit beta;
DE   AltName: Full=Laminin-2 subunit beta;
DE   AltName: Full=Laminin-6 subunit beta;
DE   AltName: Full=Laminin-8 subunit beta;
DE   Flags: Precursor;
GN   Name=LAMB1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IDA:HGNC.
DR   GO; GO:0043208; F:glycosphingolipid binding; IEA:Ensembl.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:HGNC.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
DR   GO; GO:0021812; P:neuronal-glial interaction involved in cerebral cortex radial glia guided migration; IMP:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; TAS:HGNC.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
//
ID   LAMB2_HUMAN             Reviewed;        1798 AA.
AC   P55268; Q16321;
DE   RecName: Full=Laminin subunit beta-2;
DE   AltName: Full=Laminin B1s chain;
DE   AltName: Full=Laminin-11 subunit beta;
DE   AltName: Full=Laminin-14 subunit beta;
DE   AltName: Full=Laminin-15 subunit beta;
DE   AltName: Full=Laminin-3 subunit beta;
DE   AltName: Full=Laminin-4 subunit beta;
DE   AltName: Full=Laminin-7 subunit beta;
DE   AltName: Full=Laminin-9 subunit beta;
DE   AltName: Full=S-laminin subunit beta;
DE            Short=S-LAM beta;
DE   Flags: Precursor;
GN   Name=LAMB2; Synonyms=LAMS;
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0014002; P:astrocyte development; IEA:Ensembl.
DR   GO; GO:0048677; P:axon extension involved in regeneration; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0072274; P:metanephric glomerular basement membrane development; IEA:Ensembl.
DR   GO; GO:0072249; P:metanephric glomerular visceral epithelial cell development; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0014044; P:Schwann cell development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   LAMB3_HUMAN             Reviewed;        1172 AA.
AC   Q13751; D3DT88; O14947; Q14733; Q9UJK4; Q9UJL1;
DE   RecName: Full=Laminin subunit beta-3;
DE   AltName: Full=Epiligrin subunit bata;
DE   AltName: Full=Kalinin B1 chain;
DE   AltName: Full=Kalinin subunit beta;
DE   AltName: Full=Laminin B1k chain;
DE   AltName: Full=Laminin-5 subunit beta;
DE   AltName: Full=Nicein subunit beta;
DE   Flags: Precursor;
GN   Name=LAMB3; Synonyms=LAMNB1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
//
ID   LAMB4_HUMAN             Reviewed;        1761 AA.
AC   A4D0S4; A5PKU6; B2RTT3; B5MEB9; Q86TP7; Q86XN2; Q8NBX5;
DE   RecName: Full=Laminin subunit beta-4;
DE   AltName: Full=Laminin beta-1-related protein;
DE   Flags: Precursor;
GN   Name=LAMB4;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   LAMC1_HUMAN             Reviewed;        1609 AA.
AC   P11047; Q5VYE7;
DE   RecName: Full=Laminin subunit gamma-1;
DE   AltName: Full=Laminin B2 chain;
DE   AltName: Full=Laminin-1 subunit gamma;
DE   AltName: Full=Laminin-10 subunit gamma;
DE   AltName: Full=Laminin-11 subunit gamma;
DE   AltName: Full=Laminin-2 subunit gamma;
DE   AltName: Full=Laminin-3 subunit gamma;
DE   AltName: Full=Laminin-4 subunit gamma;
DE   AltName: Full=Laminin-6 subunit gamma;
DE   AltName: Full=Laminin-7 subunit gamma;
DE   AltName: Full=Laminin-8 subunit gamma;
DE   AltName: Full=Laminin-9 subunit gamma;
DE   AltName: Full=S-laminin subunit gamma;
DE            Short=S-LAM gamma;
DE   Flags: Precursor;
GN   Name=LAMC1; Synonyms=LAMB2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IMP:HGNC.
DR   GO; GO:0043208; F:glycosphingolipid binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IDA:HGNC.
DR   GO; GO:0016477; P:cell migration; IMP:HGNC.
DR   GO; GO:0007492; P:endoderm development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; IMP:HGNC.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; IMP:HGNC.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; TAS:HGNC.
DR   GO; GO:0006461; P:protein complex assembly; IDA:HGNC.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:BHF-UCL.
//
ID   LAMC2_HUMAN             Reviewed;        1193 AA.
AC   Q13753; Q02536; Q02537; Q13752; Q14941; Q14DF7; Q5VYE8;
DE   RecName: Full=Laminin subunit gamma-2;
DE   AltName: Full=Cell-scattering factor 140 kDa subunit;
DE            Short=CSF 140 kDa subunit;
DE   AltName: Full=Epiligrin subunit gamma;
DE   AltName: Full=Kalinin subunit gamma;
DE   AltName: Full=Kalinin/nicein/epiligrin 100 kDa subunit;
DE   AltName: Full=Ladsin 140 kDa subunit;
DE   AltName: Full=Laminin B2t chain;
DE   AltName: Full=Laminin-5 subunit gamma;
DE   AltName: Full=Large adhesive scatter factor 140 kDa subunit;
DE   AltName: Full=Nicein subunit gamma;
DE   Flags: Precursor;
GN   Name=LAMC2; Synonyms=LAMB2T, LAMNB2;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; TAS:Reactome.
//
ID   LAMC3_HUMAN             Reviewed;        1575 AA.
AC   Q9Y6N6; B1APX9; B1APY0; Q59H72;
DE   RecName: Full=Laminin subunit gamma-3;
DE   AltName: Full=Laminin-12 subunit gamma;
DE   AltName: Full=Laminin-14 subunit gamma;
DE   AltName: Full=Laminin-15 subunit gamma;
DE   Flags: Precursor;
GN   Name=LAMC3;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0014002; P:astrocyte development; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0000904; P:cell morphogenesis involved in differentiation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   LAMP1_HUMAN             Reviewed;         417 AA.
AC   P11279; Q8WU33; Q96I40; Q9BRD2; Q9NP13;
DE   RecName: Full=Lysosome-associated membrane glycoprotein 1;
DE            Short=LAMP-1;
DE            Short=Lysosome-associated membrane protein 1;
DE   AltName: Full=CD107 antigen-like family member A;
DE   AltName: CD_antigen=CD107a;
DE   Flags: Precursor;
GN   Name=LAMP1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048102; P:autophagic cell death; IEA:Ensembl.
DR   GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR   GO; GO:0072594; P:establishment of protein localization to organelle; IMP:UniProt.
DR   GO; GO:0090160; P:Golgi to lysosome transport; IMP:UniProt.
DR   GO; GO:0008626; P:granzyme-mediated apoptotic signaling pathway; IMP:UniProt.
DR   GO; GO:0043323; P:positive regulation of natural killer cell degranulation; IMP:UniProt.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IMP:UniProt.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProt.
DR   GO; GO:1902513; P:regulation of organelle transport along microtubule; IMP:UniProt.
//
ID   LAMP2_HUMAN             Reviewed;         410 AA.
AC   P13473; A8K4X5; D3DTF0; Q16641; Q6Q3G8; Q96J30; Q99534; Q9UD93;
DE   RecName: Full=Lysosome-associated membrane glycoprotein 2;
DE            Short=LAMP-2;
DE            Short=Lysosome-associated membrane protein 2;
DE   AltName: Full=CD107 antigen-like family member B;
DE   AltName: CD_antigen=CD107b;
DE   Flags: Precursor;
GN   Name=LAMP2;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProt.
//
ID   LAMP3_HUMAN             Reviewed;         416 AA.
AC   Q9UQV4; D3DNS4; O94781; Q8NEC8;
DE   RecName: Full=Lysosome-associated membrane glycoprotein 3;
DE            Short=LAMP-3;
DE            Short=Lysosomal-associated membrane protein 3;
DE   AltName: Full=DC-lysosome-associated membrane glycoprotein;
DE            Short=DC LAMP;
DE   AltName: Full=Protein TSC403;
DE   AltName: CD_antigen=CD208;
DE   Flags: Precursor;
GN   Name=LAMP3; Synonyms=DCLAMP, TSC403;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   LAMP5_HUMAN             Reviewed;         280 AA.
AC   Q9UJQ1; B4DHZ7; B7Z9Z9;
DE   RecName: Full=Lysosome-associated membrane glycoprotein 5;
DE   AltName: Full=Brain and dendritic cell-associated LAMP;
DE   AltName: Full=Brain-associated LAMP-like protein;
DE            Short=BAD-LAMP;
DE   AltName: Full=Lysosome-associated membrane protein 5;
DE            Short=LAMP-5;
DE   Flags: Precursor;
GN   Name=LAMP5; Synonyms=C20orf103;
//
ID   LANC1_HUMAN             Reviewed;         399 AA.
AC   O43813;
DE   RecName: Full=LanC-like protein 1;
DE   AltName: Full=40 kDa erythrocyte membrane protein;
DE            Short=p40;
GN   Name=LANCL1; Synonyms=GPR69A;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0043295; F:glutathione binding; IDA:UniProtKB.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   LANC2_HUMAN             Reviewed;         450 AA.
AC   Q9NS86; B2R8D4; Q6NSL4; Q8TCQ3; Q9BSR1;
DE   RecName: Full=LanC-like protein 2;
DE   AltName: Full=Testis-specific adriamycin sensitivity protein;
GN   Name=LANCL2; Synonyms=GPR69B, TASP;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009789; P:positive regulation of abscisic acid-activated signaling pathway; IDA:UniProtKB.
//
ID   LANC3_HUMAN             Reviewed;         420 AA.
AC   Q6ZV70; A6NHE3;
DE   RecName: Full=LanC-like protein 3;
GN   Name=LANCL3;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   LAP2A_HUMAN             Reviewed;         694 AA.
AC   P42166; P08918; P08919; Q14860; Q16295;
DE   RecName: Full=Lamina-associated polypeptide 2, isoform alpha;
DE   AltName: Full=Thymopoietin isoform alpha;
DE            Short=TP alpha;
DE   AltName: Full=Thymopoietin-related peptide isoform alpha;
DE            Short=TPRP isoform alpha;
DE   Contains:
DE     RecName: Full=Thymopoietin;
DE              Short=TP;
DE     AltName: Full=Splenin;
DE   Contains:
DE     RecName: Full=Thymopentin;
DE     AltName: Full=TP5;
GN   Name=TMPO; Synonyms=LAP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005521; F:lamin binding; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   LAP2B_HUMAN             Reviewed;         454 AA.
AC   P42167; Q14861;
DE   RecName: Full=Lamina-associated polypeptide 2, isoforms beta/gamma;
DE   AltName: Full=Thymopoietin, isoforms beta/gamma;
DE            Short=TP beta/gamma;
DE   AltName: Full=Thymopoietin-related peptide isoforms beta/gamma;
DE            Short=TPRP isoforms beta/gamma;
DE   Contains:
DE     RecName: Full=Thymopoietin;
DE              Short=TP;
DE     AltName: Full=Splenin;
DE   Contains:
DE     RecName: Full=Thymopentin;
DE     AltName: Full=TP5;
GN   Name=TMPO; Synonyms=LAP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005521; F:lamin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LAP2_HUMAN              Reviewed;        1412 AA.
AC   Q96RT1; A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; Q1RMD0; Q86W38;
AC   Q9NR18; Q9NW48; Q9ULJ5;
DE   RecName: Full=Protein LAP2;
DE   AltName: Full=Densin-180-like protein;
DE   AltName: Full=Erbb2-interacting protein;
DE            Short=Erbin;
GN   Name=ERBB2IP; Synonyms=ERBIN, KIAA1225, LAP2;
DR   GO; GO:0005176; F:ErbB-2 class receptor binding; TAS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0045175; P:basal protein localization; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; NAS:UniProtKB.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LAP4A_HUMAN             Reviewed;         233 AA.
AC   Q15012; Q6UW22;
DE   RecName: Full=Lysosomal-associated transmembrane protein 4A;
DE   AltName: Full=Golgi 4-transmembrane-spanning transporter MTP;
GN   Name=LAPTM4A; Synonyms=KIAA0108, LAPTM4, MBNT, MTRP;
GN   ORFNames=UNQ1846/PRO3574;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LAP4B_HUMAN             Reviewed;         370 AA.
AC   Q86VI4; Q3ZCV5; Q7L909; Q86VH8; Q9H060;
DE   RecName: Full=Lysosomal-associated transmembrane protein 4B;
DE   AltName: Full=Lysosome-associated transmembrane protein 4-beta;
GN   Name=LAPTM4B; ORFNames=PSEC0001;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LAPM5_HUMAN             Reviewed;         262 AA.
AC   Q13571; Q13240; Q14698; Q3KP54;
DE   RecName: Full=Lysosomal-associated transmembrane protein 5;
DE   AltName: Full=Lysosomal-associated multitransmembrane protein 5;
DE   AltName: Full=Retinoic acid-inducible E3 protein;
GN   Name=LAPTM5; Synonyms=KIAA0085;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LAR1B_HUMAN             Reviewed;         914 AA.
AC   Q659C4; Q2YDB6; Q4W599; Q4W5B2; Q659A0; Q6P5X2; Q7Z3F7; Q86VK7;
AC   Q8N6F4; Q8N7H4; Q8NAF2; Q9H5E7; Q9NW12;
DE   RecName: Full=La-related protein 1B;
DE   AltName: Full=La ribonucleoprotein domain family member 1B;
DE   AltName: Full=La ribonucleoprotein domain family member 2;
DE   AltName: Full=La-related protein 2;
GN   Name=LARP1B; Synonyms=LARP2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   LARG2_HUMAN             Reviewed;         721 AA.
AC   Q8N3Y3; A6NN75; Q8N8Y6; Q8NAK3; Q8WY62;
DE   RecName: Full=Glycosyltransferase-like protein LARGE2;
DE            EC=2.4.-.-;
DE   AltName: Full=Glycosyltransferase-like 1B;
GN   Name=GYLTL1B; Synonyms=LARGE2; ORFNames=PP5656;
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; ISS:UniProtKB.
//
ID   LAR4B_HUMAN             Reviewed;         738 AA.
AC   Q92615; A7MD20; Q5T3R3; Q5T3R4; Q5T3R5; Q68CY4;
DE   RecName: Full=La-related protein 4B;
DE   AltName: Full=La ribonucleoprotein domain family member 4B;
DE   AltName: Full=La ribonucleoprotein domain family member 5;
DE   AltName: Full=La-related protein 5;
GN   Name=LARP4B; Synonyms=KIAA0217, LARP5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
//
ID   LARGE_HUMAN             Reviewed;         756 AA.
AC   O95461; B0QXZ7; O60348; Q17R80; Q9UGD1; Q9UGE7; Q9UGG3; Q9UGZ8;
AC   Q9UH22;
DE   RecName: Full=Glycosyltransferase-like protein LARGE1;
DE            EC=2.4.-.-;
DE   AltName: Full=Acetylglucosaminyltransferase-like 1A;
GN   Name=LARGE; Synonyms=KIAA0609, LARGE1;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; TAS:UniProtKB.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; ISS:UniProtKB.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
//
ID   LARP1_HUMAN             Reviewed;        1096 AA.
AC   Q6PKG0; O94836; Q8N4M2; Q8NB73; Q9UFD7;
DE   RecName: Full=La-related protein 1;
DE   AltName: Full=La ribonucleoprotein domain family member 1;
GN   Name=LARP1; Synonyms=KIAA0731, LARP;
DR   GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IPI:UniProtKB.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000339; F:RNA cap binding; IDA:UniProtKB.
DR   GO; GO:0008494; F:translation activator activity; IMP:UniProtKB.
DR   GO; GO:0031369; F:translation initiation factor binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:GOC.
DR   GO; GO:0031929; P:TOR signaling; IMP:UniProtKB.
DR   GO; GO:0006413; P:translational initiation; IMP:UniProtKB.
//
ID   LARP4_HUMAN             Reviewed;         724 AA.
AC   Q71RC2; A8K6T1; E9PDG5; G3XAA8; G5E976; Q5CZ97; Q6ZV14; Q96NF9;
DE   RecName: Full=La-related protein 4;
DE   AltName: Full=La ribonucleoprotein domain family member 4;
GN   Name=LARP4; ORFNames=PP13296;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   LARP6_HUMAN             Reviewed;         491 AA.
AC   Q9BRS8; Q5XKE4; Q8N3N2; Q9NUR0;
DE   RecName: Full=La-related protein 6;
DE   AltName: Full=Acheron;
DE            Short=Achn;
DE   AltName: Full=La ribonucleoprotein domain family member 6;
GN   Name=LARP6;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   LARP7_HUMAN             Reviewed;         582 AA.
AC   Q4G0J3; B2ZHN6; Q3B7A9; Q9P1S7; Q9Y3Z8;
DE   RecName: Full=La-related protein 7;
DE   AltName: Full=La ribonucleoprotein domain family member 7;
DE   AltName: Full=P-TEFb-interaction protein for 7SK stability;
DE            Short=PIP7S;
GN   Name=LARP7; ORFNames=HDCMA18P;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   LAS1L_HUMAN             Reviewed;         734 AA.
AC   Q9Y4W2; A9X410; Q5JXQ0; Q8TEN5; Q9H9V5;
DE   RecName: Full=Ribosomal biogenesis protein LAS1L;
DE   AltName: Full=Protein LAS1 homolog;
GN   Name=LAS1L; ORFNames=MSTP060;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   LAS2_HUMAN              Reviewed;         372 AA.
AC   Q8IYD9; I7HFJ6; Q6MZU3; Q6ZTL6;
DE   RecName: Full=Lung adenoma susceptibility protein 2;
DE   Flags: Precursor;
GN   Name=LAS2; Synonyms=C18orf54;
//
ID   LASP1_HUMAN             Reviewed;         261 AA.
AC   Q14847; B4DGQ0; Q96ED2; Q96IG0;
DE   RecName: Full=LIM and SH3 domain protein 1;
DE            Short=LASP-1;
DE   AltName: Full=Metastatic lymph node gene 50 protein;
DE            Short=MLN 50;
GN   Name=LASP1; Synonyms=MLN50;
DR   GO; GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; ISS:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
//
ID   LAT1L_HUMAN             Reviewed;         190 AA.
AC   Q9GIP4; Q6IPZ0; Q8MH62;
DE   RecName: Full=Putative L-type amino acid transporter 1-like protein IMAA;
DE   AltName: Full=hLAT1 3-transmembrane protein IMAA;
DE            Short=hLAT1 3TM IMAA;
DE   AltName: Full=hLAT1 3-transmembrane protein MMAA;
DE            Short=hLAT1 3TM MMAA;
GN   Name=SLC7A5P2; Synonyms=IMAA, MMAA;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
//
ID   LAT1N_HUMAN             Reviewed;         180 AA.
AC   Q8MH63;
DE   RecName: Full=Putative L-type amino acid transporter 1-like protein MLAS;
DE   AltName: Full=hLAT1 3-transmembrane protein MLAS;
DE            Short=hLAT1 3TM MLAS;
GN   Name=SLC7A5P1; Synonyms=MLAS;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
//
ID   LAT1_HUMAN              Reviewed;         507 AA.
AC   Q01650; Q8IV97; Q9UBN8; Q9UP15; Q9UQC0;
DE   RecName: Full=Large neutral amino acids transporter small subunit 1;
DE   AltName: Full=4F2 light chain;
DE            Short=4F2 LC;
DE            Short=4F2LC;
DE   AltName: Full=CD98 light chain;
DE   AltName: Full=Integral membrane protein E16;
DE   AltName: Full=L-type amino acid transporter 1;
DE            Short=hLAT1;
DE   AltName: Full=Solute carrier family 7 member 5;
DE   AltName: Full=y+ system cationic amino acid transporter;
GN   Name=SLC7A5; Synonyms=CD98LC, LAT1, MPE16;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0015804; P:neutral amino acid transport; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   LAT2_HUMAN              Reviewed;         535 AA.
AC   Q9UHI5; B2R8Q4; B4DKT4; B4DTV6; D3DS46; F2Z2J4; Q86U05; Q9UKQ6;
AC   Q9UKQ7; Q9UKQ8; Q9Y445;
DE   RecName: Full=Large neutral amino acids transporter small subunit 2;
DE   AltName: Full=L-type amino acid transporter 2;
DE            Short=hLAT2;
DE   AltName: Full=Solute carrier family 7 member 8;
GN   Name=SLC7A8; Synonyms=LAT2;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019534; F:toxin transporter activity; IDA:UniProtKB.
DR   GO; GO:0006865; P:amino acid transport; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0055065; P:metal ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0015804; P:neutral amino acid transport; ISS:UniProtKB.
DR   GO; GO:0015695; P:organic cation transport; IDA:GOC.
DR   GO; GO:0009636; P:response to toxic substance; NAS:UniProtKB.
DR   GO; GO:1901998; P:toxin transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   LAT3_HUMAN              Reviewed;         559 AA.
AC   O75387;
DE   RecName: Full=Large neutral amino acids transporter small subunit 3;
DE   AltName: Full=L-type amino acid transporter 3;
DE   AltName: Full=Prostate cancer overexpressed gene 1 protein;
DE   AltName: Full=Solute carrier family 43 member 1;
GN   Name=SLC43A1; Synonyms=LAT3, PB39, POV1;
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015804; P:neutral amino acid transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   LAT4_HUMAN              Reviewed;         569 AA.
AC   Q8N370; D3DTH9; Q5CD75; Q6IPM1; Q8NBX1; Q8NC21; Q8WZ00;
DE   RecName: Full=Large neutral amino acids transporter small subunit 4;
DE   AltName: Full=L-type amino acid transporter 4;
DE   AltName: Full=Solute carrier family 43 member 2;
GN   Name=SLC43A2; Synonyms=LAT4; ORFNames=PP7664;
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   LATH_HUMAN              Reviewed;         179 AA.
AC   Q86YQ2;
DE   RecName: Full=Putative latherin;
DE   AltName: Full=Breast cancer and salivary gland-expressed protein;
DE   Flags: Precursor;
GN   Name=LATH; Synonyms=BASE;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
//
ID   LATS2_HUMAN             Reviewed;        1088 AA.
AC   Q9NRM7; B1AM47; Q9P2X1;
DE   RecName: Full=Serine/threonine-protein kinase LATS2;
DE            EC=2.7.11.1;
DE   AltName: Full=Kinase phosphorylated during mitosis protein;
DE   AltName: Full=Large tumor suppressor homolog 2;
DE   AltName: Full=Serine/threonine-protein kinase kpm;
DE   AltName: Full=Warts-like kinase;
GN   Name=LATS2; Synonyms=KPM;
DR   GuidetoPHARMACOLOGY; 1516; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; IDA:BHF-UCL.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046620; P:regulation of organ growth; IEA:Ensembl.
//
ID   LATS1_HUMAN             Reviewed;        1130 AA.
AC   O95835; Q6PKD0;
DE   RecName: Full=Serine/threonine-protein kinase LATS1;
DE            EC=2.7.11.1;
DE   AltName: Full=Large tumor suppressor homolog 1;
DE   AltName: Full=WARTS protein kinase;
DE            Short=h-warts;
GN   Name=LATS1; Synonyms=WARTS;
DR   GuidetoPHARMACOLOGY; 1515; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0051220; P:cytoplasmic sequestering of protein; IMP:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; IDA:BHF-UCL.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IMP:BHF-UCL.
DR   GO; GO:0000819; P:sister chromatid segregation; IDA:UniProtKB.
//
ID   LAT_HUMAN               Reviewed;         262 AA.
AC   O43561; B7WPI0; C7C5T6; G5E9K3; O43919;
DE   RecName: Full=Linker for activation of T-cells family member 1;
DE   AltName: Full=36 kDa phospho-tyrosine adapter protein;
DE            Short=pp36;
DE   AltName: Full=p36-38;
GN   Name=LAT;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:HGNC.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019722; P:calcium-mediated signaling; IMP:HGNC.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IDA:HGNC.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0043303; P:mast cell degranulation; IEA:UniProtKB-KW.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IDA:GOC.
DR   GO; GO:0007265; P:Ras protein signal transduction; IMP:HGNC.
DR   GO; GO:0050863; P:regulation of T cell activation; IMP:HGNC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   LAX1_HUMAN              Reviewed;         398 AA.
AC   Q8IWV1; B7Z744; J3KP69; Q6NSZ6; Q9NXB4;
DE   RecName: Full=Lymphocyte transmembrane adapter 1;
DE   AltName: Full=Linker for activation of X cells;
DE   AltName: Full=Membrane-associated adapter protein LAX;
GN   Name=LAX1; Synonyms=LAX;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0019901; F:protein kinase binding; IDA:HGNC.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:HGNC.
DR   GO; GO:0050851; P:antigen receptor-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0042113; P:B cell activation; IDA:HGNC.
DR   GO; GO:0006955; P:immune response; IDA:HGNC.
DR   GO; GO:0048305; P:immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0000188; P:inactivation of MAPK activity; IMP:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IDA:HGNC.
//
ID   LAYN_HUMAN              Reviewed;         382 AA.
AC   Q6UX15; A6NJB0; B4DJU0; Q8TAY8; Q96NC5; Q96NF3;
DE   RecName: Full=Layilin;
DE   Flags: Precursor;
GN   Name=LAYN; ORFNames=UNQ208/PRO234;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005540; F:hyaluronic acid binding; IDA:HGNC.
//
ID   LA_HUMAN                Reviewed;         408 AA.
AC   P05455; Q15367; Q53XJ4;
DE   RecName: Full=Lupus La protein;
DE   AltName: Full=La autoantigen;
DE   AltName: Full=La ribonucleoprotein;
DE   AltName: Full=Sjoegren syndrome type B antigen;
DE            Short=SS-B;
GN   Name=SSB;
DR   GO; GO:0003729; F:mRNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000049; F:tRNA binding; TAS:ProtInc.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:ProtInc.
DR   GO; GO:0006400; P:tRNA modification; TAS:ProtInc.
//
ID   LBH_HUMAN               Reviewed;         105 AA.
AC   Q53QV2; B2RBC2; Q9H0Q1;
DE   RecName: Full=Protein LBH;
DE            Short=hLBH;
GN   Name=LBH;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LBN_HUMAN               Reviewed;        1308 AA.
AC   Q86UK5; Q86YT3; Q86YT4; Q8NG49;
DE   RecName: Full=Limbin;
DE   AltName: Full=Ellis-van Creveld syndrome protein 2;
DE            Short=EVC2;
DE   Flags: Precursor;
GN   Name=EVC2; Synonyms=LBN;
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   LBP_HUMAN               Reviewed;         481 AA.
AC   P18428; B2R938; O43438; Q92672; Q9H403; Q9UD66;
DE   RecName: Full=Lipopolysaccharide-binding protein;
DE            Short=LBP;
DE   Flags: Precursor;
GN   Name=LBP;
DR   GO; GO:0001530; F:lipopolysaccharide binding; ISS:BHF-UCL.
DR   GO; GO:0070891; F:lipoteichoic acid binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IEP:BHF-UCL.
DR   GO; GO:0006968; P:cellular defense response; ISS:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:MGI.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; IDA:MGI.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IDA:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:BHF-UCL.
DR   GO; GO:0032490; P:detection of molecule of bacterial origin; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; ISS:BHF-UCL.
DR   GO; GO:0002232; P:leukocyte chemotaxis involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IDA:BHF-UCL.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0002281; P:macrophage activation involved in immune response; ISS:BHF-UCL.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0008228; P:opsonization; ISS:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IDA:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0060265; P:positive regulation of respiratory burst involved in inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   LBR_HUMAN               Reviewed;         615 AA.
AC   Q14739; B2R5P3; Q14740; Q53GU7; Q59FE6;
DE   RecName: Full=Lamin-B receptor;
DE   AltName: Full=Integral nuclear envelope inner membrane protein;
DE   AltName: Full=LMN2R;
GN   Name=LBR;
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005521; F:lamin binding; TAS:ProtInc.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LBX1_HUMAN              Reviewed;         281 AA.
AC   P52954; B9EGA2; Q05BB2;
DE   RecName: Full=Transcription factor LBX1;
DE   AltName: Full=Ladybird homeobox protein homolog 1;
GN   Name=LBX1; Synonyms=LBX1H;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048664; P:neuron fate determination; IEA:Ensembl.
DR   GO; GO:0021920; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LBX2_HUMAN              Reviewed;         198 AA.
AC   Q6XYB7; Q7Z5Y8;
DE   RecName: Full=Transcription factor LBX2;
DE   AltName: Full=Ladybird homeobox protein homolog 2;
GN   Name=LBX2; ORFNames=LP3727;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LC1L1_HUMAN             Reviewed;         162 AA.
AC   Q5VSP4;
DE   RecName: Full=Putative lipocalin 1-like protein 1;
DE   AltName: Full=Lipocalin 1-like pseudogene 1;
DE   Flags: Precursor;
GN   Name=LCN1P1; Synonyms=LCN1L1;
//
ID   LC7L2_HUMAN             Reviewed;         392 AA.
AC   Q9Y383; B7Z500; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1;
DE   RecName: Full=Putative RNA-binding protein Luc7-like 2;
GN   Name=LUC7L2; ORFNames=CGI-59, CGI-74;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:InterPro.
//
ID   LC7L3_HUMAN             Reviewed;         432 AA.
AC   O95232; B3KN54; D3DTY1; Q6PHR9; Q9NUY0; Q9P2S7;
DE   RecName: Full=Luc7-like protein 3;
DE   AltName: Full=Cisplatin resistance-associated-overexpressed protein;
DE   AltName: Full=Luc7A;
DE   AltName: Full=Okadaic acid-inducible phosphoprotein OA48-18;
DE   AltName: Full=cAMP regulatory element-associated protein 1;
DE            Short=CRE-associated protein 1;
DE            Short=CREAP-1;
GN   Name=LUC7L3; Synonyms=CREAP1, CROP, O48;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IMP:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
//
ID   LCA5L_HUMAN             Reviewed;         670 AA.
AC   O95447; D3DSI0; Q3ZCT0;
DE   RecName: Full=Lebercilin-like protein;
DE   AltName: Full=Leber congenital amaurosis 5-like protein;
GN   Name=LCA5L; Synonyms=C21orf13;
//
ID   LCA10_HUMAN             Reviewed;         164 AA.
AC   Q71F78;
DE   RecName: Full=Putative lung carcinoma-associated protein 10;
GN   Name=LCA10;
//
ID   LCA5_HUMAN              Reviewed;         697 AA.
AC   Q86VQ0; E1P542; Q9BWX7;
DE   RecName: Full=Lebercilin;
DE   AltName: Full=Leber congenital amaurosis 5 protein;
GN   Name=LCA5; Synonyms=C6orf152;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0042073; P:intraciliary transport; IEA:Ensembl.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   LCAP_HUMAN              Reviewed;        1025 AA.
AC   Q9UIQ6; O00769; Q15145; Q59H76; Q9TNQ2; Q9TNQ3; Q9UIQ7;
DE   RecName: Full=Leucyl-cystinyl aminopeptidase;
DE            Short=Cystinyl aminopeptidase;
DE            EC=3.4.11.3;
DE   AltName: Full=Insulin-regulated membrane aminopeptidase;
DE   AltName: Full=Insulin-responsive aminopeptidase;
DE            Short=IRAP;
DE   AltName: Full=Oxytocinase;
DE            Short=OTase;
DE   AltName: Full=Placental leucine aminopeptidase;
DE            Short=P-LAP;
DE   Contains:
DE     RecName: Full=Leucyl-cystinyl aminopeptidase, pregnancy serum form;
GN   Name=LNPEP; Synonyms=OTASE;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:HGNC.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002480; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   LCAT_HUMAN              Reviewed;         440 AA.
AC   P04180; Q53XQ3;
DE   RecName: Full=Phosphatidylcholine-sterol acyltransferase;
DE            EC=2.3.1.43;
DE   AltName: Full=Lecithin-cholesterol acyltransferase;
DE   AltName: Full=Phospholipid-cholesterol acyltransferase;
DE   Flags: Precursor;
GN   Name=LCAT;
DR   GO; GO:0034186; F:apolipoprotein A-I binding; IPI:BHF-UCL.
DR   GO; GO:0004607; F:phosphatidylcholine-sterol O-acyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034435; P:cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030301; P:cholesterol transport; IDA:MGI.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IDA:UniProtKB.
DR   GO; GO:0042158; P:lipoprotein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0090107; P:regulation of high-density lipoprotein particle assembly; IEA:Ensembl.
DR   GO; GO:0043691; P:reverse cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
//
ID   LCE1A_HUMAN             Reviewed;         110 AA.
AC   Q5T7P2;
DE   RecName: Full=Late cornified envelope protein 1A;
DE   AltName: Full=Late envelope protein 1;
GN   Name=LCE1A; Synonyms=LEP1;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE1B_HUMAN             Reviewed;         118 AA.
AC   Q5T7P3; A4IF40;
DE   RecName: Full=Late cornified envelope protein 1B;
DE   AltName: Full=Late envelope protein 2;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 2A;
GN   Name=LCE1B; Synonyms=LEP2, SPRL2A;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE1C_HUMAN             Reviewed;         118 AA.
AC   Q5T751;
DE   RecName: Full=Late cornified envelope protein 1C;
DE   AltName: Full=Late envelope protein 3;
GN   Name=LCE1C; Synonyms=LEP3;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE1D_HUMAN             Reviewed;         114 AA.
AC   Q5T752;
DE   RecName: Full=Late cornified envelope protein 1D;
DE   AltName: Full=Late envelope protein 4;
GN   Name=LCE1D; Synonyms=LEP4;
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:MGI.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE1E_HUMAN             Reviewed;         118 AA.
AC   Q5T753; D3DV30;
DE   RecName: Full=Late cornified envelope protein 1E;
DE   AltName: Full=Late envelope protein 5;
GN   Name=LCE1E; Synonyms=LEP5;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE2A_HUMAN             Reviewed;         106 AA.
AC   Q5TA79; A4QMZ9;
DE   RecName: Full=Late cornified envelope protein 2A;
DE   AltName: Full=Late envelope protein 9;
GN   Name=LCE2A; Synonyms=LEP9;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE1F_HUMAN             Reviewed;         118 AA.
AC   Q5T754;
DE   RecName: Full=Late cornified envelope protein 1F;
DE   AltName: Full=Late envelope protein 6;
GN   Name=LCE1F; Synonyms=LEP6;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE2C_HUMAN             Reviewed;         110 AA.
AC   Q5TA81;
DE   RecName: Full=Late cornified envelope protein 2C;
DE   AltName: Full=Late envelope protein 11;
GN   Name=LCE2C; Synonyms=LEP11;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE2D_HUMAN             Reviewed;         110 AA.
AC   Q5TA82; A1L4M8;
DE   RecName: Full=Late cornified envelope protein 2D;
DE   AltName: Full=Late envelope protein 12;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 1A;
GN   Name=LCE2D; Synonyms=LEP12, SPRL1A;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE2B_HUMAN             Reviewed;         110 AA.
AC   O14633; Q5TA80;
DE   RecName: Full=Late cornified envelope protein 2B;
DE   AltName: Full=Late envelope protein 10;
DE   AltName: Full=Skin-specific protein Xp5;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 1B;
GN   Name=LCE2B; Synonyms=LEP10, SPRL1B, XP5;
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE3B_HUMAN             Reviewed;          95 AA.
AC   Q5TA77;
DE   RecName: Full=Late cornified envelope protein 3B;
DE   AltName: Full=Late envelope protein 14;
GN   Name=LCE3B; Synonyms=LEP14;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE3C_HUMAN             Reviewed;          94 AA.
AC   Q5T5A8; A1L420;
DE   RecName: Full=Late cornified envelope protein 3C;
DE   AltName: Full=Late envelope protein 15;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 3A;
GN   Name=LCE3C; Synonyms=LEP15, SPRL3A;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE3D_HUMAN             Reviewed;          92 AA.
AC   Q9BYE3; Q3MIL1;
DE   RecName: Full=Late cornified envelope protein 3D;
DE   AltName: Full=Late envelope protein 16;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 6A;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 6B;
GN   Name=LCE3D; Synonyms=LEP16, SPRL6A, SPRL6B;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE3E_HUMAN             Reviewed;          92 AA.
AC   Q5T5B0; A2RRM6;
DE   RecName: Full=Late cornified envelope protein 3E;
DE   AltName: Full=Late envelope protein 17;
GN   Name=LCE3E; Synonyms=LEP17;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE3A_HUMAN             Reviewed;          89 AA.
AC   Q5TA76;
DE   RecName: Full=Late cornified envelope protein 3A;
DE   AltName: Full=Late envelope protein 13;
GN   Name=LCE3A; Synonyms=LEP13;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE4A_HUMAN             Reviewed;          99 AA.
AC   Q5TA78; Q14D97;
DE   RecName: Full=Late cornified envelope protein 4A;
DE   AltName: Full=Late envelope protein 8;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 4A;
GN   Name=LCE4A; Synonyms=LEP8, SPRL4A;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE5A_HUMAN             Reviewed;         118 AA.
AC   Q5TCM9;
DE   RecName: Full=Late cornified envelope protein 5A;
DE   AltName: Full=Late envelope protein 18;
DE   AltName: Full=Small proline-rich-like epidermal differentiation complex protein 5A;
GN   Name=LCE5A; Synonyms=LEP18, SPRL5A;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCE6A_HUMAN             Reviewed;          80 AA.
AC   A0A183;
DE   RecName: Full=Late cornified envelope protein 6A;
GN   Name=LCE6A; Synonyms=C1orf44;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   LCHN_HUMAN              Reviewed;         455 AA.
AC   A4D1U4; Q9ULS3;
DE   RecName: Full=Protein LCHN;
GN   Name=LCHN; Synonyms=KIAA1147;
//
ID   LCK_HUMAN               Reviewed;         509 AA.
AC   P06239; D3DPP8; P07100; Q12850; Q13152; Q5TDH8; Q5TDH9; Q7RTZ3;
AC   Q96DW4; Q9NYT8;
DE   RecName: Full=Tyrosine-protein kinase Lck;
DE            EC=2.7.10.2;
DE   AltName: Full=Leukocyte C-terminal Src kinase;
DE            Short=LSK;
DE   AltName: Full=Lymphocyte cell-specific protein-tyrosine kinase;
DE   AltName: Full=Protein YT16;
DE   AltName: Full=Proto-oncogene Lck;
DE   AltName: Full=T cell-specific protein-tyrosine kinase;
DE   AltName: Full=p56-LCK;
GN   Name=LCK;
DR   GuidetoPHARMACOLOGY; 2053; -.
DR   GO; GO:0003823; F:antigen binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.
DR   GO; GO:0042610; F:CD8 receptor binding; IPI:UniProtKB.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IEP:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IDA:UniProtKB.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IEA:Ensembl.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0051249; P:regulation of lymphocyte activation; NAS:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0030217; P:T cell differentiation; IMP:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   LCLT1_HUMAN             Reviewed;         414 AA.
AC   Q6UWP7; A6H8Z7; Q8N1Q7;
DE   RecName: Full=Lysocardiolipin acyltransferase 1;
DE            EC=2.3.1.-;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 8;
DE            Short=1-AGP acyltransferase 8;
DE            Short=1-AGPAT 8;
DE   AltName: Full=Acyl-CoA:lysocardiolipin acyltransferase 1;
GN   Name=LCLAT1; Synonyms=AGPAT8, ALCAT1, LYCAT; ORFNames=UNQ1849/PRO3579;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   LCMT1_HUMAN             Reviewed;         334 AA.
AC   Q9UIC8; A6NL89; A8K770; Q53FC5; Q96CI5; Q9H6I9; Q9NTG4; Q9Y378;
DE   RecName: Full=Leucine carboxyl methyltransferase 1;
DE            EC=2.1.1.233;
DE   AltName: Full=Protein-leucine O-methyltransferase;
DE   AltName: Full=[Phosphatase 2A protein]-leucine-carboxy methyltransferase 1;
GN   Name=LCMT1; Synonyms=LCMT; ORFNames=CGI-68;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003880; F:protein C-terminal carboxyl O-methyltransferase activity; IDA:MGI.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006481; P:C-terminal protein methylation; IDA:MGI.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IMP:MGI.
DR   GO; GO:0006479; P:protein methylation; IMP:MGI.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:MGI.
DR   GO; GO:0090266; P:regulation of mitotic cell cycle spindle assembly checkpoint; IMP:MGI.
//
ID   LCN10_HUMAN             Reviewed;         187 AA.
AC   Q6JVE6; A2RUU3; B0QZ79;
DE   RecName: Full=Epididymal-specific lipocalin-10;
DE   Flags: Precursor;
GN   Name=LCN10;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LCN12_HUMAN             Reviewed;         192 AA.
AC   Q6JVE5; A2AMJ7;
DE   RecName: Full=Epididymal-specific lipocalin-12;
DE   Flags: Precursor;
GN   Name=LCN12;
DR   GO; GO:0001972; F:retinoic acid binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   LCN15_HUMAN             Reviewed;         184 AA.
AC   Q6UWW0;
DE   RecName: Full=Lipocalin-15;
DE   Flags: Precursor;
GN   Name=LCN15; ORFNames=UNQ2541/PRO6093;
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   LCN1_HUMAN              Reviewed;         176 AA.
AC   P31025; Q5T8A1;
DE   RecName: Full=Lipocalin-1;
DE   AltName: Full=Tear lipocalin;
DE            Short=Tlc;
DE   AltName: Full=Tear prealbumin;
DE            Short=TP;
DE   AltName: Full=Von Ebner gland protein;
DE            Short=VEG protein;
DE   Flags: Precursor;
GN   Name=LCN1; Synonyms=VEGP;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LCN6_HUMAN              Reviewed;         163 AA.
AC   P62502; B0QZ80; Q71SF6;
DE   RecName: Full=Epididymal-specific lipocalin-6;
DE   AltName: Full=Lipocalin-5;
DE   Flags: Precursor;
GN   Name=LCN6; Synonyms=LCN5; ORFNames=UNQ643/PRO1273;
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
//
ID   LCN8_HUMAN              Reviewed;         175 AA.
AC   Q6JVE9; A1L4A8; A6NMN9; Q5T5R4;
DE   RecName: Full=Epididymal-specific lipocalin-8;
DE   Flags: Precursor;
GN   Name=LCN8; Synonyms=LCN5;
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LCN9_HUMAN              Reviewed;         176 AA.
AC   Q8WX39; C9J5F0; Q6JVE7;
DE   RecName: Full=Epididymal-specific lipocalin-9;
DE   AltName: Full=MUP-like lipocalin;
DE   Flags: Precursor;
GN   Name=LCN9;
DR   GO; GO:0005550; F:pheromone binding; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   LCNL1_HUMAN             Reviewed;         164 AA.
AC   Q6ZST4;
DE   RecName: Full=Lipocalin-like 1 protein;
GN   Name=LCNL1;
//
ID   LCORL_HUMAN             Reviewed;         602 AA.
AC   Q8N3X6; Q96NK1;
DE   RecName: Full=Ligand-dependent nuclear receptor corepressor-like protein;
DE            Short=LCoR-like protein;
GN   Name=LCORL;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   LCOR_HUMAN              Reviewed;         433 AA.
AC   Q96JN0; D3DR47; Q5VW16; Q7Z723; Q86T32; Q86T33; Q8N3L6;
DE   RecName: Full=Ligand-dependent corepressor;
DE            Short=LCoR;
DE   AltName: Full=Mblk1-related protein 2;
GN   Name=LCOR; Synonyms=KIAA1795, MLR2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   LCP2_HUMAN              Reviewed;         533 AA.
AC   Q13094; A8KA25; Q53XV4;
DE   RecName: Full=Lymphocyte cytosolic protein 2;
DE   AltName: Full=SH2 domain-containing leukocyte protein of 76 kDa;
DE   AltName: Full=SLP-76 tyrosine phosphoprotein;
DE            Short=SLP76;
GN   Name=LCP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050663; P:cytokine secretion; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045576; P:mast cell activation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   LCTL_HUMAN              Reviewed;         567 AA.
AC   Q6UWM7; B3KQY0;
DE   RecName: Full=Lactase-like protein;
DE   AltName: Full=Klotho/lactase-phlorizin hydrolase-related protein;
DE   Flags: Precursor;
GN   Name=LCTL; Synonyms=KLPH; ORFNames=UNQ3022/PRO9820;
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   LDB1_HUMAN              Reviewed;         411 AA.
AC   Q86U70; B4DUC4; O75479; O96010; Q1EQX1; Q9UGM4;
DE   RecName: Full=LIM domain-binding protein 1;
DE            Short=LDB-1;
DE   AltName: Full=Carboxyl-terminal LIM domain-binding protein 2;
DE            Short=CLIM-2;
DE   AltName: Full=LIM domain-binding factor CLIM2;
DE            Short=hLdb1;
DE   AltName: Full=Nuclear LIM interactor;
GN   Name=LDB1; Synonyms=CLIM2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0030274; F:LIM domain binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0022607; P:cellular component assembly; IEA:Ensembl.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0010669; P:epithelial structure maintenance; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0060322; P:head development; IEA:Ensembl.
DR   GO; GO:0043973; P:histone H3-K4 acetylation; ISS:BHF-UCL.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0046985; P:positive regulation of hemoglobin biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:ProtInc.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0000972; P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; ISS:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   LDB2_HUMAN              Reviewed;         373 AA.
AC   O43679; O60619; O75480;
DE   RecName: Full=LIM domain-binding protein 2;
DE            Short=LDB-2;
DE   AltName: Full=Carboxyl-terminal LIM domain-binding protein 1;
DE            Short=CLIM-1;
DE   AltName: Full=LIM domain-binding factor CLIM1;
GN   Name=LDB2; Synonyms=CLIM1;
DR   GO; GO:0030274; F:LIM domain binding; ISS:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0010669; P:epithelial structure maintenance; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0044089; P:positive regulation of cellular component biogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
//
ID   LDB3_HUMAN              Reviewed;         727 AA.
AC   O75112; A2TDB7; A6NIV4; B4E3K3; Q5K6N9; Q5K6P0; Q5K6P1; Q96FH2;
AC   Q9Y4Z3; Q9Y4Z4; Q9Y4Z5;
DE   RecName: Full=LIM domain-binding protein 3;
DE   AltName: Full=Protein cypher;
DE   AltName: Full=Z-band alternatively spliced PDZ-motif protein;
GN   Name=LDB3; Synonyms=KIAA0613, ZASP;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
//
ID   LDH6A_HUMAN             Reviewed;         332 AA.
AC   Q6ZMR3; D3DQY5;
DE   RecName: Full=L-lactate dehydrogenase A-like 6A;
DE            EC=1.1.1.27;
GN   Name=LDHAL6A; Synonyms=LDHL2;
DR   GO; GO:0004459; F:L-lactate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
//
ID   LDH6B_HUMAN             Reviewed;         381 AA.
AC   Q9BYZ2; Q6DUY4; Q96LI2;
DE   RecName: Full=L-lactate dehydrogenase A-like 6B;
DE            EC=1.1.1.27;
GN   Name=LDHAL6B; Synonyms=LDHAL6, LDHL;
DR   GO; GO:0004459; F:L-lactate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
//
ID   LDHA_HUMAN              Reviewed;         332 AA.
AC   P00338; B4DKQ2; B7Z5E3; D3DQY3; F8W819; Q53G53; Q6IBM7; Q6ZNV1;
AC   Q9UDE8; Q9UDE9;
DE   RecName: Full=L-lactate dehydrogenase A chain;
DE            Short=LDH-A;
DE            EC=1.1.1.27;
DE   AltName: Full=Cell proliferation-inducing gene 19 protein;
DE   AltName: Full=LDH muscle subunit;
DE            Short=LDH-M;
DE   AltName: Full=Renal carcinoma antigen NY-REN-59;
GN   Name=LDHA; ORFNames=PIG19;
DR   GO; GO:0004459; F:L-lactate dehydrogenase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0006096; P:glycolytic process; NAS:UniProtKB.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProtKB.
//
ID   LDHB_HUMAN              Reviewed;         334 AA.
AC   P07195;
DE   RecName: Full=L-lactate dehydrogenase B chain;
DE            Short=LDH-B;
DE            EC=1.1.1.27;
DE   AltName: Full=LDH heart subunit;
DE            Short=LDH-H;
DE   AltName: Full=Renal carcinoma antigen NY-REN-46;
GN   Name=LDHB;
DR   GO; GO:0004459; F:L-lactate dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0006089; P:lactate metabolic process; IEA:Ensembl.
DR   GO; GO:0019674; P:NAD metabolic process; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LDHC_HUMAN              Reviewed;         332 AA.
AC   P07864; D3DQY4; Q6GSG8; Q7Z7J4;
DE   RecName: Full=L-lactate dehydrogenase C chain;
DE            Short=LDH-C;
DE            EC=1.1.1.27;
DE   AltName: Full=Cancer/testis antigen 32;
DE            Short=CT32;
DE   AltName: Full=LDH testis subunit;
DE   AltName: Full=LDH-X;
GN   Name=LDHC; Synonyms=LDH3, LDHX;
DR   GO; GO:0004459; F:L-lactate dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0006754; P:ATP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0019244; P:lactate biosynthetic process from pyruvate; IEA:Ensembl.
DR   GO; GO:0019516; P:lactate oxidation; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
//
ID   LDHD_HUMAN              Reviewed;         507 AA.
AC   Q86WU2; Q8IZK5;
DE   RecName: Full=Probable D-lactate dehydrogenase, mitochondrial;
DE            Short=DLD;
DE            Short=Lactate dehydrogenase D;
DE            EC=1.1.2.4;
DE   Flags: Precursor;
GN   Name=LDHD;
DR   GO; GO:0004458; F:D-lactate dehydrogenase (cytochrome) activity; IEA:UniProtKB-EC.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
//
ID   LDLR_HUMAN              Reviewed;         860 AA.
AC   P01130; B4DII3; B4DJZ8; B4DR00; B4DTQ3; C0JYY8; H0YLU8; H0YNT7;
AC   Q53ZD9; Q59FQ1; Q9UDH7;
DE   RecName: Full=Low-density lipoprotein receptor;
DE            Short=LDL receptor;
DE   Flags: Precursor;
GN   Name=LDLR;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030229; F:very-low-density lipoprotein particle receptor activity; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0070508; P:cholesterol import; ISS:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030301; P:cholesterol transport; IMP:HGNC.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; IMP:HGNC.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042159; P:lipoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0015914; P:phospholipid transport; ISS:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:Reactome.
DR   GO; GO:0010899; P:regulation of phosphatidylcholine catabolic process; ISS:BHF-UCL.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   LDOC1_HUMAN             Reviewed;         146 AA.
AC   O95751; Q6IAR6;
DE   RecName: Full=Protein LDOC1;
DE   AltName: Full=Leucine zipper protein down-regulated in cancer cells;
GN   Name=LDOC1; Synonyms=BCUR1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   LDOCL_HUMAN             Reviewed;         239 AA.
AC   Q6ICC9; Q6ZTR1;
DE   RecName: Full=Protein LDOC1L;
DE   AltName: Full=Leucine zipper protein down-regulated in cancer cells-like;
DE   AltName: Full=Mammalian retrotransposon-derived protein 6;
GN   Name=LDOC1L; Synonyms=MAR6, MART6;
//
ID   LEAP2_HUMAN             Reviewed;          77 AA.
AC   Q969E1; D3DQ91;
DE   RecName: Full=Liver-expressed antimicrobial peptide 2;
DE            Short=LEAP-2;
DE   Flags: Precursor;
GN   Name=LEAP2;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
//
ID   LECT1_HUMAN             Reviewed;         334 AA.
AC   O75829; Q5TAM4; Q8TAY6; Q9UM18;
DE   RecName: Full=Leukocyte cell-derived chemotaxin 1;
DE   Contains:
DE     RecName: Full=Chondrosurfactant protein;
DE              Short=CH-SP;
DE   Contains:
DE     RecName: Full=Chondromodulin-1;
DE     AltName: Full=Chondromodulin-I;
DE              Short=ChM-I;
DE   Flags: Precursor;
GN   Name=LECT1; Synonyms=CHMI;
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006029; P:proteoglycan metabolic process; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   LECT2_HUMAN             Reviewed;         151 AA.
AC   O14960; B2RA90; O14565; Q52M49;
DE   RecName: Full=Leukocyte cell-derived chemotaxin-2;
DE            Short=LECT-2;
DE            Short=hLECT2;
DE   Flags: Precursor;
GN   Name=LECT2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   LEF1_HUMAN              Reviewed;         399 AA.
AC   Q9UJU2; B4DG38; B7Z8E2; E9PDK3; Q3ZCU4; Q9HAZ0;
DE   RecName: Full=Lymphoid enhancer-binding factor 1;
DE            Short=LEF-1;
DE   AltName: Full=T cell-specific transcription factor 1-alpha;
DE            Short=TCF1-alpha;
GN   Name=LEF1;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
DR   GO; GO:0035326; F:enhancer binding; IDA:UniProtKB.
DR   GO; GO:0030284; F:estrogen receptor activity; IDA:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0046632; P:alpha-beta T cell differentiation; IBA:RefGenome.
DR   GO; GO:0060033; P:anatomical structure regression; IEA:Ensembl.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IBA:RefGenome.
DR   GO; GO:1902262; P:apoptotic process involved in patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0042100; P:B cell proliferation; IBA:RefGenome.
DR   GO; GO:0030509; P:BMP signaling pathway; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IMP:BHF-UCL.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IDA:UniProtKB.
DR   GO; GO:0060710; P:chorio-allantoic fusion; IBA:RefGenome.
DR   GO; GO:0021542; P:dentate gyrus development; IBA:RefGenome.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IBA:RefGenome.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0048069; P:eye pigmentation; IBA:RefGenome.
DR   GO; GO:0060325; P:face morphogenesis; IBA:RefGenome.
DR   GO; GO:0021873; P:forebrain neuroblast division; IBA:RefGenome.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IBA:RefGenome.
DR   GO; GO:0021861; P:forebrain radial glial cell differentiation; IBA:RefGenome.
DR   GO; GO:0021943; P:formation of radial glial scaffolds; IBA:RefGenome.
DR   GO; GO:0043966; P:histone H3 acetylation; IMP:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.
DR   GO; GO:0021854; P:hypothalamus development; IBA:RefGenome.
DR   GO; GO:0030879; P:mammary gland development; IBA:RefGenome.
DR   GO; GO:0048747; P:muscle fiber development; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0071866; P:negative regulation of apoptotic process in bone marrow; IMP:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0071899; P:negative regulation of estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0032696; P:negative regulation of interleukin-13 production; IDA:UniProtKB.
DR   GO; GO:0032713; P:negative regulation of interleukin-4 production; IDA:UniProtKB.
DR   GO; GO:0032714; P:negative regulation of interleukin-5 production; IDA:UniProtKB.
DR   GO; GO:0045843; P:negative regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0030223; P:neutrophil differentiation; IMP:UniProtKB.
DR   GO; GO:0071895; P:odontoblast differentiation; IBA:RefGenome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0048341; P:paraxial mesoderm formation; IBA:RefGenome.
DR   GO; GO:0001569; P:patterning of blood vessels; IBA:RefGenome.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0090068; P:positive regulation of cell cycle process; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0071864; P:positive regulation of cell proliferation in bone marrow; IMP:UniProtKB.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:AgBase.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IBA:RefGenome.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IBA:RefGenome.
DR   GO; GO:0002040; P:sprouting angiogenesis; IBA:RefGenome.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IDA:GOC.
DR   GO; GO:0033153; P:T cell receptor V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0045063; P:T-helper 1 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0061153; P:trachea gland development; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
//
ID   LEG10_HUMAN             Reviewed;         142 AA.
AC   Q05315; C5HZ13; C5HZ14; Q0VDE3;
DE   RecName: Full=Galectin-10;
DE            Short=Gal-10;
DE   AltName: Full=Charcot-Leyden crystal protein;
DE            Short=CLC;
DE   AltName: Full=Eosinophil lysophospholipase;
DE   AltName: Full=Lysolecithin acylhydrolase;
GN   Name=CLC; Synonyms=LGALS10, LGALS10A;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0046006; P:regulation of activated T cell proliferation; IMP:UniProtKB.
DR   GO; GO:0002667; P:regulation of T cell anergy; IMP:UniProtKB.
DR   GO; GO:0002724; P:regulation of T cell cytokine production; IMP:UniProtKB.
DR   GO; GO:0070231; P:T cell apoptotic process; IDA:UniProtKB.
//
ID   LEG12_HUMAN             Reviewed;         336 AA.
AC   Q96DT0; B2R9N2; Q96DS9; Q96PR9; Q9H258; Q9H259; Q9NZ02;
DE   RecName: Full=Galectin-12;
DE            Short=Gal-12;
DE   AltName: Full=Galectin-related inhibitor of proliferation;
GN   Name=LGALS12; Synonyms=GRIP1;
DR   GO; GO:0030395; F:lactose binding; IDA:MGI.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:MGI.
//
ID   LEG16_HUMAN             Reviewed;         142 AA.
AC   A8MUM7; C5HZ26;
DE   RecName: Full=Galectin-16;
GN   Name=LGALS16;
DR   GO; GO:0030395; F:lactose binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0070234; P:positive regulation of T cell apoptotic process; IDA:UniProtKB.
//
ID   LEG1_HUMAN              Reviewed;         135 AA.
AC   P09382; B2R5E8; Q9UDK5;
DE   RecName: Full=Galectin-1;
DE            Short=Gal-1;
DE   AltName: Full=14 kDa laminin-binding protein;
DE            Short=HLBP14;
DE   AltName: Full=14 kDa lectin;
DE   AltName: Full=Beta-galactoside-binding lectin L-14-I;
DE   AltName: Full=Galaptin;
DE   AltName: Full=HBL;
DE   AltName: Full=HPL;
DE   AltName: Full=Lactose-binding lectin 1;
DE   AltName: Full=Lectin galactoside-binding soluble 1;
DE   AltName: Full=Putative MAPK-activating protein PM12;
DE   AltName: Full=S-Lac lectin 1;
GN   Name=LGALS1;
DR   GO; GO:0016936; F:galactoside binding; IEA:InterPro.
DR   GO; GO:0030395; F:lactose binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0002317; P:plasma cell differentiation; IEA:Ensembl.
DR   GO; GO:0034120; P:positive regulation of erythrocyte aggregation; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
//
ID   LEG2_HUMAN              Reviewed;         132 AA.
AC   P05162; Q6FGY4;
DE   RecName: Full=Galectin-2;
DE            Short=Gal-2;
DE   AltName: Full=Beta-galactoside-binding lectin L-14-II;
DE   AltName: Full=HL14;
DE   AltName: Full=Lactose-binding lectin 2;
DE   AltName: Full=S-Lac lectin 2;
GN   Name=LGALS2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016936; F:galactoside binding; IEA:Ensembl.
//
ID   LEG3_HUMAN              Reviewed;         250 AA.
AC   P17931; B2RC38; Q16005; Q6IBA7; Q96J47;
DE   RecName: Full=Galectin-3;
DE            Short=Gal-3;
DE   AltName: Full=35 kDa lectin;
DE   AltName: Full=Carbohydrate-binding protein 35;
DE            Short=CBP 35;
DE   AltName: Full=Galactose-specific lectin 3;
DE   AltName: Full=Galactoside-binding protein;
DE            Short=GALBP;
DE   AltName: Full=IgE-binding protein;
DE   AltName: Full=L-31;
DE   AltName: Full=Laminin-binding protein;
DE   AltName: Full=Lectin L-29;
DE   AltName: Full=Mac-2 antigen;
GN   Name=LGALS3; Synonyms=MAC2;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.
DR   GO; GO:0019863; F:IgE binding; IDA:BHF-UCL.
DR   GO; GO:0043236; F:laminin binding; IDA:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048246; P:macrophage chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0071674; P:mononuclear cell migration; IDA:BHF-UCL.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IDA:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:2000521; P:negative regulation of immunological synapse formation; ISS:BHF-UCL.
DR   GO; GO:2001189; P:negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; ISS:BHF-UCL.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0071677; P:positive regulation of mononuclear cell migration; IDA:BHF-UCL.
DR   GO; GO:1902041; P:regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:0070232; P:regulation of T cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0042129; P:regulation of T cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   LEG4_HUMAN              Reviewed;         323 AA.
AC   P56470;
DE   RecName: Full=Galectin-4;
DE            Short=Gal-4;
DE   AltName: Full=Antigen NY-CO-27;
DE   AltName: Full=L-36 lactose-binding protein;
DE            Short=L36LBP;
DE   AltName: Full=Lactose-binding lectin 4;
GN   Name=LGALS4;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
//
ID   LEG8_HUMAN              Reviewed;         317 AA.
AC   O00214; O15215; Q5T3P5; Q5T3Q4; Q8TEV1; Q96B92; Q9BXC8; Q9H584;
AC   Q9H585; Q9UEZ6; Q9UP32; Q9UP33; Q9UP34;
DE   RecName: Full=Galectin-8;
DE            Short=Gal-8;
DE   AltName: Full=Po66 carbohydrate-binding protein;
DE            Short=Po66-CBP;
DE   AltName: Full=Prostate carcinoma tumor antigen 1;
DE            Short=PCTA-1;
GN   Name=LGALS8;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002317; P:plasma cell differentiation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
//
ID   LEG7_HUMAN              Reviewed;         136 AA.
AC   P47929; Q6IB87;
DE   RecName: Full=Galectin-7;
DE            Short=Gal-7;
DE   AltName: Full=HKL-14;
DE   AltName: Full=PI7;
DE   AltName: Full=p53-induced gene 1 protein;
GN   Name=LGALS7; Synonyms=PIG1;
GN   and
GN   Name=LGALS7B;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; TAS:ProtInc.
//
ID   LEG9B_HUMAN             Reviewed;         356 AA.
AC   Q3B8N2; A6NLF8; A8K2J8;
DE   RecName: Full=Galectin-9B;
DE            Short=Gal-9B;
DE   AltName: Full=Galectin-9-like protein A;
GN   Name=LGALS9B;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   LEG9C_HUMAN             Reviewed;         356 AA.
AC   Q6DKI2; B0AZM7;
DE   RecName: Full=Galectin-9C;
DE            Short=Gal-9C;
DE   AltName: Full=Galectin-9-like protein B;
GN   Name=LGALS9C;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   LEG9_HUMAN              Reviewed;         355 AA.
AC   O00182; A7VJG6; O14532; O75028; Q3B8N1; Q53FQ0; Q9NQ58;
DE   RecName: Full=Galectin-9;
DE            Short=Gal-9;
DE   AltName: Full=Ecalectin;
DE   AltName: Full=Tumor antigen HOM-HD-21;
GN   Name=LGALS9;
DR   GO; GO:0030246; F:carbohydrate binding; IDA:UniProtKB.
DR   GO; GO:0005534; F:galactose binding; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   LEGL_HUMAN              Reviewed;         172 AA.
AC   Q3ZCW2; B2RBG8; D6W5E8; Q6P5T6; Q9P005;
DE   RecName: Full=Galectin-related protein;
DE   AltName: Full=Lectin galactoside-binding-like protein;
GN   Name=LGALSL; Synonyms=GRP; ORFNames=HSPC159;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   LEKR1_HUMAN             Reviewed;         388 AA.
AC   Q6ZMV7;
DE   RecName: Full=Leucine-, glutamate- and lysine-rich protein 1;
GN   Name=LEKR1;
//
ID   LELP1_HUMAN             Reviewed;          98 AA.
AC   Q5T871; A1L4E1;
DE   RecName: Full=Late cornified envelope-like proline-rich protein 1;
DE   AltName: Full=Novel small proline-rich protein;
GN   Name=LELP1;
//
ID   LEMD2_HUMAN             Reviewed;         503 AA.
AC   Q8NC56; B4DVH5; E7EVT2; Q5T972; Q5T974;
DE   RecName: Full=LEM domain-containing protein 2;
DE            Short=hLEM2;
GN   Name=LEMD2;
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IGI:MGI.
//
ID   LEMD1_HUMAN             Reviewed;         181 AA.
AC   Q68G75; Q6L9T9; Q6L9U0; Q6L9U1; Q6L9U2; Q6L9U3; Q6L9U4;
DE   RecName: Full=LEM domain-containing protein 1;
DE   AltName: Full=Cancer/testis antigen 50;
DE            Short=CT50;
DE   AltName: Full=LEM domain protein 1;
DE            Short=LEMP-1;
GN   Name=LEMD1;
//
ID   LENEP_HUMAN             Reviewed;          61 AA.
AC   Q9Y5L5; B5BUM1; Q5T1A4;
DE   RecName: Full=Lens epithelial cell protein LEP503;
GN   Name=LENEP; Synonyms=LEP503;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   LENG1_HUMAN             Reviewed;         264 AA.
AC   Q96BZ8; Q9HCU7;
DE   RecName: Full=Leukocyte receptor cluster member 1;
GN   Name=LENG1;
//
ID   LENG8_HUMAN             Reviewed;         779 AA.
AC   Q96PV6; B0VJY9; Q8IZ27; Q8NCX6;
DE   RecName: Full=Leukocyte receptor cluster member 8;
GN   Name=LENG8; Synonyms=KIAA1932;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   LENG9_HUMAN             Reviewed;         501 AA.
AC   Q96B70; B2VAM3;
DE   RecName: Full=Leukocyte receptor cluster member 9;
GN   Name=LENG9;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   LEO1_HUMAN              Reviewed;         666 AA.
AC   Q8WVC0; Q96N99;
DE   RecName: Full=RNA polymerase-associated protein LEO1;
DE   AltName: Full=Replicative senescence down-regulated leo1-like protein;
GN   Name=LEO1; Synonyms=RDL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0031442; P:positive regulation of mRNA 3'-end processing; IMP:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   LEPR_HUMAN              Reviewed;        1165 AA.
AC   P48357; Q13592; Q13593; Q13594; Q92919; Q92920; Q92921;
DE   RecName: Full=Leptin receptor;
DE            Short=LEP-R;
DE   AltName: Full=HuB219;
DE   AltName: Full=OB receptor;
DE            Short=OB-R;
DE   AltName: CD_antigen=CD295;
DE   Flags: Precursor;
GN   Name=LEPR; Synonyms=DB, OBR;
DR   GuidetoPHARMACOLOGY; 1712; -.
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0051346; P:negative regulation of hydrolase activity; IEA:Ensembl.
//
ID   LEP_HUMAN               Reviewed;         167 AA.
AC   P41159; O15158; Q56A88;
DE   RecName: Full=Leptin;
DE   AltName: Full=Obese protein;
DE   AltName: Full=Obesity factor;
DE   Flags: Precursor;
GN   Name=LEP; Synonyms=OB, OBS;
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0008343; P:adult feeding behavior; ISS:HGNC.
DR   GO; GO:0008206; P:bile acid metabolic process; IEA:Ensembl.
DR   GO; GO:0035630; P:bone mineralization involved in bone maturation; IEA:Ensembl.
DR   GO; GO:0071298; P:cellular response to L-ascorbic acid; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:ProtInc.
DR   GO; GO:0009062; P:fatty acid catabolic process; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0006114; P:glycerol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0033210; P:leptin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032099; P:negative regulation of appetite; ISS:HGNC.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0070093; P:negative regulation of glucagon secretion; IEA:Ensembl.
DR   GO; GO:2000486; P:negative regulation of glutamine transport; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045906; P:negative regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IDA:DFLAT.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0048639; P:positive regulation of developmental growth; IDA:DFLAT.
DR   GO; GO:0046881; P:positive regulation of follicle-stimulating hormone secretion; IEA:Ensembl.
DR   GO; GO:2000491; P:positive regulation of hepatic stellate cell activation; IEA:Ensembl.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043270; P:positive regulation of ion transport; IEA:Ensembl.
DR   GO; GO:0033686; P:positive regulation of luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0045639; P:positive regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:2000366; P:positive regulation of STAT protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0030300; P:regulation of intestinal cholesterol absorption; IEA:Ensembl.
DR   GO; GO:0060587; P:regulation of lipoprotein lipid oxidation; IEA:Ensembl.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0007260; P:tyrosine phosphorylation of STAT protein; IEA:Ensembl.
//
ID   LERL1_HUMAN             Reviewed;         131 AA.
AC   O95214; E9PHP8; Q9BW48;
DE   RecName: Full=Leptin receptor overlapping transcript-like 1;
DE   AltName: Full=Endospanin-2;
GN   Name=LEPROTL1; ORFNames=My047, UNQ577/PRO1139;
//
ID   LETM1_HUMAN             Reviewed;         739 AA.
AC   O95202; B4DED2; Q9UF65;
DE   RecName: Full=LETM1 and EF-hand domain-containing protein 1, mitochondrial;
DE   AltName: Full=Leucine zipper-EF-hand-containing transmembrane protein 1;
DE   Flags: Precursor;
GN   Name=LETM1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042407; P:cristae formation; IMP:UniProtKB.
//
ID   LETM2_HUMAN             Reviewed;         491 AA.
AC   Q2VYF4; A6NMG3; Q8NCR2; Q96LL1;
DE   RecName: Full=LETM1 domain-containing protein LETM2, mitochondrial;
DE   AltName: Full=LETM1 and EF-hand domain-containing protein 2;
DE   AltName: Full=Leucine zipper-EF-hand-containing transmembrane protein 1-like;
DE   Flags: Precursor;
GN   Name=LETM2;
//
ID   LEU1_HUMAN              Reviewed;          78 AA.
AC   O43261; Q547G6; Q8TE10; Q96QY5;
DE   RecName: Full=Leukemia-associated protein 1;
DE   AltName: Full=Deleted in lymphocytic leukemia 1;
DE   AltName: Full=HBV X-transactivated gene 6 protein;
DE   AltName: Full=HBV XAg-transactivated protein 6;
GN   Name=DLEU1; Synonyms=LEU1, XTP6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LEU7_HUMAN              Reviewed;         221 AA.
AC   Q6UYE1; Q2M2E4; Q6ZT82;
DE   RecName: Full=Leukemia-associated protein 7;
DE   AltName: Full=Deleted in lymphocytic leukemia 7;
GN   Name=DLEU7; Synonyms=LEU7;
//
ID   LEUK_HUMAN              Reviewed;         400 AA.
AC   P16150; A8K9B1;
DE   RecName: Full=Leukosialin;
DE   AltName: Full=Galactoglycoprotein;
DE            Short=GALGP;
DE   AltName: Full=Leukocyte sialoglycoprotein;
DE   AltName: Full=Sialophorin;
DE   AltName: CD_antigen=CD43;
DE   Flags: Precursor;
GN   Name=SPN; Synonyms=CD43;
DR   GO; GO:0005515; F:protein binding; IPI:MTBBASE.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:MGI.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; TAS:ProtInc.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0001808; P:negative regulation of type IV hypersensitivity; IEA:Ensembl.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:MGI.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:Ensembl.
DR   GO; GO:0001562; P:response to protozoan; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
//
ID   LEUTX_HUMAN             Reviewed;         168 AA.
AC   A8MZ59;
DE   RecName: Full=Leucine-twenty homeobox;
GN   Name=LEUTX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   LFA3_HUMAN              Reviewed;         250 AA.
AC   P19256; A8K7G5; Q5U053; Q6IB65; Q96KI9;
DE   RecName: Full=Lymphocyte function-associated antigen 3;
DE            Short=Ag3;
DE   AltName: Full=Surface glycoprotein LFA-3;
DE   AltName: CD_antigen=CD58;
DE   Flags: Precursor;
GN   Name=CD58; Synonyms=LFA3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProt.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProt.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IDA:UniProt.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IMP:UniProt.
//
ID   LFG1_HUMAN              Reviewed;         371 AA.
AC   Q7Z429; B3KXM7; O43836; Q8IVW7;
DE   RecName: Full=Protein lifeguard 1;
DE   AltName: Full=Glutamate [NMDA] receptor-associated protein 1;
DE   AltName: Full=NMDA receptor glutamate-binding subunit;
DE   AltName: Full=Putative MAPK-activating protein PM02;
DE   AltName: Full=Transmembrane BAX inhibitor motif-containing protein 3;
GN   Name=GRINA; Synonyms=LFG1, NMDARA1, TMBIM3;
//
ID   LFG2_HUMAN              Reviewed;         316 AA.
AC   Q9BWQ8; A8K1W6; Q9UJY9; Q9Y2F7;
DE   RecName: Full=Protein lifeguard 2;
DE   AltName: Full=Fas apoptotic inhibitory molecule 2;
DE   AltName: Full=Neural membrane protein 35;
DE   AltName: Full=Transmembrane BAX inhibitor motif-containing protein 2;
GN   Name=FAIM2; Synonyms=KIAA0950, LFG, LFG2, NMP35, TMBIM2;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0021681; P:cerebellar granular layer development; ISS:UniProtKB.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; ISS:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IMP:UniProtKB.
//
ID   LFG3_HUMAN              Reviewed;         311 AA.
AC   Q969X1; B3KQY6; Q8N1R3; Q8TAM3; Q96K13;
DE   RecName: Full=Protein lifeguard 3;
DE   AltName: Full=Protein RECS1 homolog;
DE   AltName: Full=Transmembrane BAX inhibitor motif-containing protein 1;
GN   Name=TMBIM1; Synonyms=LFG3, RECS1; ORFNames=PP1201, PSEC0158;
//
ID   LFG4_HUMAN              Reviewed;         238 AA.
AC   Q9HC24; Q542Z6; Q9UHY5; Q9Y3C2;
DE   RecName: Full=Protein lifeguard 4;
DE   AltName: Full=Golgi anti-apoptotic protein;
DE   AltName: Full=Protein S1R;
DE   AltName: Full=Transmembrane BAX inhibitor motif-containing protein 4;
DE   AltName: Full=Z-protein;
GN   Name=TMBIM4; Synonyms=GAAP, LFG4; ORFNames=CGI-119;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0050848; P:regulation of calcium-mediated signaling; IDA:UniProtKB.
//
ID   LFNG_HUMAN              Reviewed;         379 AA.
AC   Q8NES3; B3KTY6; B5MCR5; O00589; Q96C39; Q9UJW5;
DE   RecName: Full=Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe;
DE            EC=2.4.1.222;
DE   AltName: Full=O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;
GN   Name=LFNG;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0033829; F:O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; ISS:UniProt.
DR   GO; GO:0007386; P:compartment pattern specification; IEA:Ensembl.
DR   GO; GO:0007143; P:female meiotic division; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; ISS:UniProt.
DR   GO; GO:0014807; P:regulation of somitogenesis; IMP:UniProt.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   LFTY2_HUMAN             Reviewed;         366 AA.
AC   O00292; B3KNH4; B4E332; E9PDM4; O75611; Q5TE89; Q8NBQ9;
DE   RecName: Full=Left-right determination factor 2;
DE   AltName: Full=Endometrial bleeding-associated factor;
DE   AltName: Full=Left-right determination factor A;
DE   AltName: Full=Protein lefty-2;
DE   AltName: Full=Protein lefty-A;
DE   AltName: Full=Transforming growth factor beta-4;
DE            Short=TGF-beta-4;
DE   Flags: Precursor;
GN   Name=LEFTY2; Synonyms=EBAF, LEFTA, LEFTYA, TGFB4; ORFNames=PSEC0024;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   LFTY1_HUMAN             Reviewed;         366 AA.
AC   O75610; B2R7U0; Q53H67; Q5TE94;
DE   RecName: Full=Left-right determination factor 1;
DE   AltName: Full=Left-right determination factor B;
DE   AltName: Full=Protein lefty-1;
DE   AltName: Full=Protein lefty-B;
DE   Flags: Precursor;
GN   Name=LEFTY1; Synonyms=LEFTB, LEFTYB; ORFNames=UNQ278/PRO317;
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   LG3BP_HUMAN             Reviewed;         585 AA.
AC   Q08380; Q7M4S0; Q9UCH8; Q9UCH9; Q9UCI0;
DE   RecName: Full=Galectin-3-binding protein;
DE   AltName: Full=Basement membrane autoantigen p105;
DE   AltName: Full=Lectin galactoside-binding soluble 3-binding protein;
DE   AltName: Full=Mac-2-binding protein;
DE            Short=MAC2BP;
DE            Short=Mac-2 BP;
DE   AltName: Full=Tumor-associated antigen 90K;
DE   Flags: Precursor;
GN   Name=LGALS3BP; Synonyms=M2BP;
DR   GO; GO:0005044; F:scavenger receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LGAT1_HUMAN             Reviewed;         370 AA.
AC   Q92604; Q53YL2;
DE   RecName: Full=Acyl-CoA:lysophosphatidylglycerol acyltransferase 1;
DE            EC=2.3.1.-;
GN   Name=LPGAT1; Synonyms=FAM34A, KIAA0205;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LGI1_HUMAN              Reviewed;         557 AA.
AC   O95970; A8K0Z1; B4E1S0; Q5W001; Q5W002; Q8NI23; Q96LF5;
DE   RecName: Full=Leucine-rich glioma-inactivated protein 1;
DE   AltName: Full=Epitempin-1;
DE   Flags: Precursor;
GN   Name=LGI1; Synonyms=EPT; ORFNames=UNQ775/PRO1569;
DR   GO; GO:0005515; F:protein binding; IPI:DFLAT.
DR   GO; GO:0005102; F:receptor binding; IPI:DFLAT.
DR   GO; GO:0007411; P:axon guidance; IMP:DFLAT.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0031175; P:neuron projection development; IMP:DFLAT.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:DFLAT.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
//
ID   LGI2_HUMAN              Reviewed;         545 AA.
AC   Q8N0V4; Q3MIN2; Q8NDW6; Q96PX2; Q9NVK4;
DE   RecName: Full=Leucine-rich repeat LGI family member 2;
DE   AltName: Full=LGI1-like protein 2;
DE   AltName: Full=Leucine-rich glioma-inactivated protein 2;
DE   Flags: Precursor;
GN   Name=LGI2; Synonyms=KIAA1916, LGIL2;
//
ID   LGI3_HUMAN              Reviewed;         548 AA.
AC   Q8N145; Q86TL4; Q8N296;
DE   RecName: Full=Leucine-rich repeat LGI family member 3;
DE   AltName: Full=LGI1-like protein 4;
DE   AltName: Full=Leucine-rich glioma-inactivated protein 3;
DE   Flags: Precursor;
GN   Name=LGI3; Synonyms=LGIL4; ORFNames=UNQ8190/PRO23199;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
//
ID   LGI4_HUMAN              Reviewed;         537 AA.
AC   Q8N135; B2RN53; B9EGS7; Q5M8T1;
DE   RecName: Full=Leucine-rich repeat LGI family member 4;
DE   AltName: Full=LGI1-like protein 3;
DE   AltName: Full=Leucine-rich glioma-inactivated protein 4;
DE   Flags: Precursor;
GN   Name=LGI4; Synonyms=LGIL3; ORFNames=UNQ6515/PRO21485;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0014009; P:glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
//
ID   LGMN_HUMAN              Reviewed;         433 AA.
AC   Q99538; O00123; Q9BTY1;
DE   RecName: Full=Legumain;
DE            EC=3.4.22.34;
DE   AltName: Full=Asparaginyl endopeptidase;
DE   AltName: Full=Protease, cysteine 1;
DE   Flags: Precursor;
GN   Name=LGMN; Synonyms=PRSC1;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:1901185; P:negative regulation of ERBB signaling pathway; ISS:UniProtKB.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0032801; P:receptor catabolic process; ISS:UniProtKB.
DR   GO; GO:0003014; P:renal system process; ISS:UniProtKB.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042359; P:vitamin D metabolic process; TAS:Reactome.
//
ID   LGR4_HUMAN              Reviewed;         951 AA.
AC   Q9BXB1; A6NCH3; G5E9B3; Q8N537; Q9NYD1;
DE   RecName: Full=Leucine-rich repeat-containing G-protein coupled receptor 4;
DE   AltName: Full=G-protein coupled receptor 48;
DE   Flags: Precursor;
GN   Name=LGR4; Synonyms=GPR48;
DR   GuidetoPHARMACOLOGY; 147; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; ISS:UniProtKB.
DR   GO; GO:0046849; P:bone remodeling; ISS:UniProtKB.
DR   GO; GO:0061290; P:canonical Wnt signaling pathway involved in metanephric kidney development; IEA:Ensembl.
DR   GO; GO:0072202; P:cell differentiation involved in metanephros development; IEA:Ensembl.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0072224; P:metanephric glomerulus development; IEA:Ensembl.
DR   GO; GO:0072282; P:metanephric nephron tubule morphogenesis; IEA:Ensembl.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   LGR5_HUMAN              Reviewed;         907 AA.
AC   O75473; D8MCT0; Q4VAM0; Q4VAM2; Q9UP75;
DE   RecName: Full=Leucine-rich repeat-containing G-protein coupled receptor 5;
DE   AltName: Full=G-protein coupled receptor 49;
DE   AltName: Full=G-protein coupled receptor 67;
DE   AltName: Full=G-protein coupled receptor HG38;
DE   Flags: Precursor;
GN   Name=LGR5; Synonyms=GPR49, GPR67;
DR   GuidetoPHARMACOLOGY; 148; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016500; F:protein-hormone receptor activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
//
ID   LGR6_HUMAN              Reviewed;         967 AA.
AC   Q9HBX8; Q5T509; Q5T512; Q6UY15; Q86VU0; Q96K69; Q9BYD7;
DE   RecName: Full=Leucine-rich repeat-containing G-protein coupled receptor 6;
DE   Flags: Precursor;
GN   Name=LGR6; ORFNames=UNQ6427/PRO21331, VTS20631;
DR   GuidetoPHARMACOLOGY; 149; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   LGSN_HUMAN              Reviewed;         509 AA.
AC   Q5TDP6; A1L421; Q0PVN9; Q0PVP0; Q9NYJ0;
DE   RecName: Full=Lengsin;
DE   AltName: Full=Glutamate-ammonia ligase domain-containing protein 1;
DE   AltName: Full=Lens glutamine synthase-like;
GN   Name=LGSN; Synonyms=GLULD1, LGS;
DR   GO; GO:0004356; F:glutamate-ammonia ligase activity; IEA:InterPro.
DR   GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
//
ID   LGUL_HUMAN              Reviewed;         184 AA.
AC   Q04760; B2R6P7; B4DDV0; P78375; Q59EL0; Q5TZW3; Q96FC0; Q96J41;
DE   RecName: Full=Lactoylglutathione lyase;
DE            EC=4.4.1.5;
DE   AltName: Full=Aldoketomutase;
DE   AltName: Full=Glyoxalase I;
DE            Short=Glx I;
DE   AltName: Full=Ketone-aldehyde mutase;
DE   AltName: Full=Methylglyoxalase;
DE   AltName: Full=S-D-lactoylglutathione methylglyoxal lyase;
GN   Name=GLO1;
DR   GO; GO:0004462; F:lactoylglutathione lyase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:Ensembl.
DR   GO; GO:0009438; P:methylglyoxal metabolic process; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   LHFP_HUMAN              Reviewed;         200 AA.
AC   Q9Y693; B2R7M2; Q53FC0; Q96SH5;
DE   RecName: Full=Lipoma HMGIC fusion partner;
DE   Flags: Precursor;
GN   Name=LHFP;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
//
ID   LHPL1_HUMAN             Reviewed;         220 AA.
AC   Q86WI0; A8K1N1; Q496M9; Q496N0; Q6UXU2;
DE   RecName: Full=Lipoma HMGIC fusion partner-like 1 protein;
DE   Flags: Precursor;
GN   Name=LHFPL1; ORFNames=UNQ5824/PRO19643;
//
ID   LHPL2_HUMAN             Reviewed;         228 AA.
AC   Q6ZUX7; B2RMQ6; Q7Z5P0; Q92605;
DE   RecName: Full=Lipoma HMGIC fusion partner-like 2 protein;
GN   Name=LHFPL2; Synonyms=KIAA0206;
//
ID   LHPL3_HUMAN             Reviewed;         236 AA.
AC   Q86UP9; A1L383; A4D0Q5;
DE   RecName: Full=Lipoma HMGIC fusion partner-like 3 protein;
GN   Name=LHFPL3; Synonyms=LHFPL4;
//
ID   LHPL4_HUMAN             Reviewed;         247 AA.
AC   Q7Z7J7; A6NH76; Q29RV7;
DE   RecName: Full=Lipoma HMGIC fusion partner-like 4 protein;
GN   Name=LHFPL4;
//
ID   LHPP_HUMAN              Reviewed;         270 AA.
AC   Q9H008; B3KP20; Q2TBE9; Q5VUV9; Q5VUW0;
DE   RecName: Full=Phospholysine phosphohistidine inorganic pyrophosphate phosphatase;
DE            Short=hLHPP;
DE            EC=3.1.3.-;
DE            EC=3.6.1.1;
GN   Name=LHPP;
DR   GO; GO:0004427; F:inorganic diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0008969; F:phosphohistidine phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; IDA:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
//
ID   LHX1_HUMAN              Reviewed;         406 AA.
AC   P48742; Q3MIW0;
DE   RecName: Full=LIM/homeobox protein Lhx1;
DE            Short=LIM homeobox protein 1;
DE   AltName: Full=Homeobox protein Lim-1;
DE            Short=hLim-1;
GN   Name=LHX1; Synonyms=LIM-1, LIM1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; ISS:UniProtKB.
DR   GO; GO:0021937; P:cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; ISS:UniProtKB.
DR   GO; GO:0060067; P:cervix development; ISS:UniProtKB.
DR   GO; GO:0072049; P:comma-shaped body morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0001705; P:ectoderm formation; ISS:UniProtKB.
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001706; P:endoderm formation; ISS:UniProtKB.
DR   GO; GO:0060429; P:epithelium development; ISS:UniProtKB.
DR   GO; GO:0021871; P:forebrain regionalization; ISS:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; ISS:UniProtKB.
DR   GO; GO:0060322; P:head development; ISS:UniProtKB.
DR   GO; GO:0035852; P:horizontal cell localization; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0097477; P:lateral motor column neuron migration; ISS:UniProtKB.
DR   GO; GO:0072177; P:mesonephric duct development; IEA:Ensembl.
DR   GO; GO:0072278; P:metanephric comma-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0072224; P:metanephric glomerulus development; IEA:Ensembl.
DR   GO; GO:0035502; P:metanephric part of ureteric bud development; IEA:Ensembl.
DR   GO; GO:0072283; P:metanephric renal vesicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0072284; P:metanephric S-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0035849; P:nephric duct elongation; IEA:Ensembl.
DR   GO; GO:0072178; P:nephric duct morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0060066; P:oviduct development; ISS:UniProtKB.
DR   GO; GO:0035846; P:oviduct epithelium development; ISS:UniProtKB.
DR   GO; GO:0061205; P:paramesonephric duct development; ISS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; ISS:UniProtKB.
DR   GO; GO:2000744; P:positive regulation of anterior head development; ISS:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.
DR   GO; GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.
DR   GO; GO:2000768; P:positive regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; ISS:UniProtKB.
DR   GO; GO:0090009; P:primitive streak formation; ISS:UniProtKB.
DR   GO; GO:0048793; P:pronephros development; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0072077; P:renal vesicle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
DR   GO; GO:0072050; P:S-shaped body morphogenesis; ISS:UniProtKB.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; ISS:UniProtKB.
DR   GO; GO:0035847; P:uterine epithelium development; ISS:UniProtKB.
DR   GO; GO:0060065; P:uterus development; ISS:UniProtKB.
DR   GO; GO:0060068; P:vagina development; ISS:UniProtKB.
DR   GO; GO:0021517; P:ventral spinal cord development; IEA:Ensembl.
//
ID   LHX2_HUMAN              Reviewed;         406 AA.
AC   P50458; O95860; Q52M57; Q8N1Z3;
DE   RecName: Full=LIM/homeobox protein Lhx2;
DE            Short=Homeobox protein LH-2;
DE            Short=LIM homeobox protein 2;
GN   Name=LHX2; Synonyms=LH2;
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0021978; P:telencephalon regionalization; IEA:Ensembl.
//
ID   LHX3_HUMAN              Reviewed;         397 AA.
AC   Q9UBR4; Q5TB39; Q5TB40; Q9NZB5; Q9P0I8; Q9P0I9;
DE   RecName: Full=LIM/homeobox protein Lhx3;
DE            Short=LIM homeobox protein 3;
GN   Name=LHX3;
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048839; P:inner ear development; IEP:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0021526; P:medial motor column neuron differentiation; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0021521; P:ventral spinal cord interneuron specification; IEA:Ensembl.
//
ID   LHX9_HUMAN              Reviewed;         397 AA.
AC   Q9NQ69; Q5VUE2; Q5VUE3; Q5VUE6; Q86UH2; Q9BYU6; Q9NQ70;
DE   RecName: Full=LIM/homeobox protein Lhx9;
DE            Short=LIM homeobox protein 9;
GN   Name=LHX9;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0035262; P:gonad morphogenesis; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
//
ID   LHX5_HUMAN              Reviewed;         402 AA.
AC   Q9H2C1; Q32MA4;
DE   RecName: Full=LIM/homeobox protein Lhx5;
DE            Short=LIM homeobox protein 5;
GN   Name=LHX5;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0021937; P:cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LHX4_HUMAN              Reviewed;         390 AA.
AC   Q969G2; Q8NHE0; Q8NHM1; Q8TCJ1; Q8WWX2; Q969W2;
DE   RecName: Full=LIM/homeobox protein Lhx4;
DE            Short=LIM homeobox protein 4;
GN   Name=LHX4;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0021526; P:medial motor column neuron differentiation; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LHX6_HUMAN              Reviewed;         363 AA.
AC   Q9UPM6; A6PVQ1; A6PVQ2; A8K1B2; B7Z4D0; H0YN76; Q5T7S7; Q5T7S8;
AC   Q9NTK3; Q9UPM5;
DE   RecName: Full=LIM/homeobox protein Lhx6;
DE            Short=LIM homeobox protein 6;
DE   AltName: Full=LIM/homeobox protein Lhx6.1;
GN   Name=LHX6; Synonyms=LHX6.1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048469; P:cell maturation; ISS:UniProtKB.
DR   GO; GO:0021853; P:cerebral cortex GABAergic interneuron migration; ISS:UniProtKB.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; ISS:UniProtKB.
DR   GO; GO:0021800; P:cerebral cortex tangential migration; ISS:UniProtKB.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0021877; P:forebrain neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LHX8_HUMAN              Reviewed;         356 AA.
AC   Q68G74; E9PGE3;
DE   RecName: Full=LIM/homeobox protein Lhx8;
DE            Short=LIM homeobox protein 8;
GN   Name=LHX8;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LIAS_HUMAN              Reviewed;         372 AA.
AC   O43766; A8K873; C9JCF6; Q8IV62;
DE   RecName: Full=Lipoyl synthase, mitochondrial;
DE            EC=2.8.1.8;
DE   AltName: Full=Lipoate synthase;
DE            Short=LS;
DE            Short=Lip-syn;
DE   AltName: Full=Lipoic acid synthase;
DE   Flags: Precursor;
GN   Name=LIAS; Synonyms=LAS; ORFNames=HUSSY-01;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016992; F:lipoate synthase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0009107; P:lipoate biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0009249; P:protein lipoylation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
//
ID   LICH_HUMAN              Reviewed;         399 AA.
AC   P38571; B2RBH5; D3DR29; Q16529; Q53H21; Q5T074; Q5T771; Q96EJ0;
DE   RecName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase;
DE            Short=Acid cholesteryl ester hydrolase;
DE            Short=LAL;
DE            EC=3.1.1.13;
DE   AltName: Full=Cholesteryl esterase;
DE   AltName: Full=Lipase A;
DE   AltName: Full=Sterol esterase;
DE   Flags: Precursor;
GN   Name=LIPA;
DR   GO; GO:0016298; F:lipase activity; IDA:UniProtKB.
DR   GO; GO:0004771; F:sterol esterase activity; IDA:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0048771; P:tissue remodeling; IEA:Ensembl.
//
ID   LIFR_HUMAN              Reviewed;        1097 AA.
AC   P42702; Q6LCD9;
DE   RecName: Full=Leukemia inhibitory factor receptor;
DE            Short=LIF receptor;
DE            Short=LIF-R;
DE   AltName: CD_antigen=CD118;
DE   Flags: Precursor;
GN   Name=LIFR;
DR   GO; GO:0005127; F:ciliary neurotrophic factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0004923; F:leukemia inhibitory factor receptor activity; IDA:MGI.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0070120; P:ciliary neurotrophic factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:MGI.
DR   GO; GO:0048861; P:leukemia inhibitory factor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0038165; P:oncostatin-M-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
//
ID   LIF_HUMAN               Reviewed;         202 AA.
AC   P15018; B2RCW7; B5MC23; Q52LZ2;
DE   RecName: Full=Leukemia inhibitory factor;
DE            Short=LIF;
DE   AltName: Full=Differentiation-stimulating factor;
DE            Short=D factor;
DE   AltName: Full=Melanoma-derived LPL inhibitor;
DE            Short=MLPLI;
DE   AltName: INN=Emfilermin;
DE   Flags: Precursor;
GN   Name=LIF; Synonyms=HILDA;
DR   GO; GO:0005125; F:cytokine activity; IDA:MGI.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005146; F:leukemia inhibitory factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0001135; F:RNA polymerase II transcription factor recruiting transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0048861; P:leukemia inhibitory factor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
DR   GO; GO:0060426; P:lung vasculature development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IDA:MGI.
DR   GO; GO:0045835; P:negative regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:1901676; P:positive regulation of histone H3-K27 acetylation; IDA:BHF-UCL.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IDA:MGI.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
DR   GO; GO:0072108; P:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0033141; P:positive regulation of peptidyl-serine phosphorylation of STAT protein; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:1900182; P:positive regulation of protein localization to nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IDA:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0072307; P:regulation of metanephric nephron tubule epithelial cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0060708; P:spongiotrophoblast differentiation; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
DR   GO; GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
//
ID   LIGO1_HUMAN             Reviewed;         620 AA.
AC   Q96FE5; D3DW80; Q6NUK3; Q6UXM3; Q6VVG0; Q6VVG1; Q6VVG2; Q8N3K5;
AC   Q96K52;
DE   RecName: Full=Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1;
DE   AltName: Full=Leucine-rich repeat and immunoglobulin domain-containing protein 1;
DE   AltName: Full=Leucine-rich repeat neuronal protein 1;
DE   AltName: Full=Leucine-rich repeat neuronal protein 6A;
DE   Flags: Precursor;
GN   Name=LINGO1; Synonyms=LERN1, LRRN6A; ORFNames=UNQ201/PRO227;
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
//
ID   LIGO2_HUMAN             Reviewed;         606 AA.
AC   Q7L985; A8K4K7; B2RPM5; Q6ZMD0;
DE   RecName: Full=Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2;
DE   AltName: Full=Leucine-rich repeat neuronal protein 3;
DE   AltName: Full=Leucine-rich repeat neuronal protein 6C;
DE   Flags: Precursor;
GN   Name=LINGO2; Synonyms=LERN3, LRRN6C; ORFNames=UNQ9234/PRO31993;
//
ID   LIGO3_HUMAN             Reviewed;         592 AA.
AC   P0C6S8;
DE   RecName: Full=Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3;
DE   AltName: Full=Leucine-rich repeat neuronal protein 2;
DE   AltName: Full=Leucine-rich repeat neuronal protein 6B;
DE   Flags: Precursor;
GN   Name=LINGO3; Synonyms=LERN2, LRRN6B;
//
ID   LIGO4_HUMAN             Reviewed;         593 AA.
AC   Q6UY18;
DE   RecName: Full=Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4;
DE   AltName: Full=Leucine-rich repeat neuronal protein 6D;
DE   Flags: Precursor;
GN   Name=LINGO4; Synonyms=LRRN6D; ORFNames=UNQ9248/PRO34002;
//
ID   LIM3L_HUMAN             Reviewed;         117 AA.
AC   P0CW20; C9K0W2;
DE   RecName: Full=LIM and senescent cell antigen-like-containing domain protein 3-like;
GN   Name=LIMS3L;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   LIMA1_HUMAN             Reviewed;         759 AA.
AC   Q9UHB6; B2RB09; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96;
AC   Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5;
DE   RecName: Full=LIM domain and actin-binding protein 1;
DE   AltName: Full=Epithelial protein lost in neoplasm;
GN   Name=LIMA1; Synonyms=EPLIN, SREBP3; ORFNames=PP624;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0003785; F:actin monomer binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051017; P:actin filament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0030835; P:negative regulation of actin filament depolymerization; IDA:UniProtKB.
DR   GO; GO:0031529; P:ruffle organization; IDA:UniProtKB.
//
ID   LIMC1_HUMAN             Reviewed;        1083 AA.
AC   Q9UPQ0; A8MXC3; E9PHM7; Q503B5; Q5CZB1; Q5CZB6; Q5H9S8; Q68E07;
AC   Q6PJ44; Q7Z3G5; Q8N3S9; Q8N6M2;
DE   RecName: Full=LIM and calponin homology domains-containing protein 1;
GN   Name=LIMCH1; Synonyms=KIAA1102;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:InterPro.
//
ID   LIMD1_HUMAN             Reviewed;         676 AA.
AC   Q9UGP4; Q17RQ1; Q9BQQ9; Q9NQ47;
DE   RecName: Full=LIM domain-containing protein 1;
GN   Name=LIMD1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:MGI.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0035195; P:gene silencing by miRNA; IMP:MGI.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0035331; P:negative regulation of hippo signaling; IDA:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; ISS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LIME1_HUMAN             Reviewed;         295 AA.
AC   Q9H400; E1P5K5; E1P5K6; Q5JWJ2; Q6XYB3; Q9NX69;
DE   RecName: Full=Lck-interacting transmembrane adapter 1;
DE            Short=Lck-interacting membrane protein;
DE   AltName: Full=Lck-interacting molecule;
GN   Name=LIME1; Synonyms=LIME; ORFNames=LP8067;
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:InterPro.
//
ID   LIMD2_HUMAN             Reviewed;         127 AA.
AC   Q9BT23; D3DU16; Q96S91;
DE   RecName: Full=LIM domain-containing protein 2;
GN   Name=LIMD2; ORFNames=SB143;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   LIMK2_HUMAN             Reviewed;         638 AA.
AC   P53671; A8K6H5; Q7KZ80; Q7L3H5; Q96E10; Q99464; Q9UFU0;
DE   RecName: Full=LIM domain kinase 2;
DE            Short=LIMK-2;
DE            EC=2.7.11.1;
GN   Name=LIMK2;
DR   GuidetoPHARMACOLOGY; 2055; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   LIMS1_HUMAN             Reviewed;         325 AA.
AC   P48059; B2RAJ4; B7Z483; B7Z7R3; B7Z907; Q53TE0; Q9BS44;
DE   RecName: Full=LIM and senescent cell antigen-like-containing domain protein 1;
DE   AltName: Full=Particularly interesting new Cys-His protein 1;
DE            Short=PINCH-1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-48;
GN   Name=LIMS1; Synonyms=PINCH, PINCH1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007569; P:cell aging; TAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   LIMS2_HUMAN             Reviewed;         341 AA.
AC   Q7Z4I7; A6NLH0; B4DMV1; F5H6E6; Q7Z4I2; Q7Z4I6; Q7Z4I8; Q8NFE7;
AC   Q9HA13;
DE   RecName: Full=LIM and senescent cell antigen-like-containing domain protein 2;
DE   AltName: Full=LIM-like protein 2;
DE   AltName: Full=Particularly interesting new Cys-His protein 2;
DE            Short=PINCH-2;
GN   Name=LIMS2; Synonyms=PINCH2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; IEA:Ensembl.
DR   GO; GO:2001046; P:positive regulation of integrin-mediated signaling pathway; IEA:Ensembl.
//
ID   LIMK1_HUMAN             Reviewed;         647 AA.
AC   P53667; B7Z6I8; D3DXF4; D3DXF5; O15283; Q15820; Q15821; Q75MU3;
AC   Q9Y5Q1;
DE   RecName: Full=LIM domain kinase 1;
DE            Short=LIMK-1;
DE            EC=2.7.11.1;
GN   Name=LIMK1; Synonyms=LIMK;
DR   GuidetoPHARMACOLOGY; 2054; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0031072; F:heat shock protein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.
DR   GO; GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LIMS3_HUMAN             Reviewed;         117 AA.
AC   P0CW19; B4DPH6; Q9HB10;
DE   RecName: Full=LIM and senescent cell antigen-like-containing domain protein 3;
DE   AltName: Full=Particularly interesting new Cys-His protein 3;
DE            Short=PINCH-3;
GN   Name=LIMS3; Synonyms=PINCH3;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   LIN37_HUMAN             Reviewed;         246 AA.
AC   Q96GY3; A8KAQ1; O14557; Q7Z2T9;
DE   RecName: Full=Protein lin-37 homolog;
DE   AltName: Full=Antolefinin;
GN   Name=LIN37; ORFNames=MSTP064;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
//
ID   LIN41_HUMAN             Reviewed;         868 AA.
AC   Q2Q1W2;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM71;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein lin-41 homolog;
DE   AltName: Full=Tripartite motif-containing protein 71;
GN   Name=TRIM71; Synonyms=LIN41;
DR   GO; GO:0035198; F:miRNA binding; ISS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0010586; P:miRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; ISS:UniProtKB.
DR   GO; GO:2000637; P:positive regulation of gene silencing by miRNA; IEA:Ensembl.
DR   GO; GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
DR   GO; GO:0060964; P:regulation of gene silencing by miRNA; ISS:UniProtKB.
DR   GO; GO:2000177; P:regulation of neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0072089; P:stem cell proliferation; ISS:UniProtKB.
//
ID   LIN52_HUMAN             Reviewed;         116 AA.
AC   Q52LA3;
DE   RecName: Full=Protein lin-52 homolog;
GN   Name=LIN52; Synonyms=C14orf46;
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   LIN54_HUMAN             Reviewed;         749 AA.
AC   Q6MZP7; Q32M68; Q32M69; Q6N071; Q76B60;
DE   RecName: Full=Protein lin-54 homolog;
DE   AltName: Full=CXC domain-containing protein 1;
GN   Name=LIN54; Synonyms=CXCDC1, KIAA2037;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LIN7A_HUMAN             Reviewed;         233 AA.
AC   O14910; A4FTY3; Q147W1; Q6LES3; Q7LDS4;
DE   RecName: Full=Protein lin-7 homolog A;
DE            Short=Lin-7A;
DE            Short=hLin-7;
DE   AltName: Full=Mammalian lin-seven protein 1;
DE            Short=MALS-1;
DE   AltName: Full=Tax interaction protein 33;
DE            Short=TIP-33;
DE   AltName: Full=Vertebrate lin-7 homolog 1;
DE            Short=Veli-1;
GN   Name=LIN7A; Synonyms=MALS1, VELI1;
DR   GO; GO:0097016; F:L27 domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048489; P:synaptic vesicle transport; IEA:Ensembl.
//
ID   LIN7B_HUMAN             Reviewed;         207 AA.
AC   Q9HAP6;
DE   RecName: Full=Protein lin-7 homolog B;
DE            Short=Lin-7B;
DE            Short=hLin7B;
DE   AltName: Full=Mammalian lin-seven protein 2;
DE            Short=MALS-2;
DE   AltName: Full=Vertebrate lin-7 homolog 2;
DE            Short=Veli-2;
DE            Short=hVeli2;
GN   Name=LIN7B; Synonyms=MALS2, VELI2; ORFNames=UNQ3116/PRO10200;
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   LIN7C_HUMAN             Reviewed;         197 AA.
AC   Q9NUP9;
DE   RecName: Full=Protein lin-7 homolog C;
DE            Short=Lin-7C;
DE   AltName: Full=Mammalian lin-seven protein 3;
DE            Short=MALS-3;
DE   AltName: Full=Vertebrate lin-7 homolog 3;
DE            Short=Veli-3;
GN   Name=LIN7C; Synonyms=MALS3, VELI3;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0097016; F:L27 domain binding; IDA:UniProt.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IMP:UniProt.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   LIN9_HUMAN              Reviewed;         542 AA.
AC   Q5TKA1; Q5U5L8; Q5U7E1; Q6PI55; Q6ZTV4; Q7Z3J1;
DE   RecName: Full=Protein lin-9 homolog;
DE            Short=HuLin-9;
DE            Short=hLin-9;
DE   AltName: Full=Beta subunit-associated regulator of apoptosis;
DE   AltName: Full=TUDOR gene similar protein;
DE   AltName: Full=Type I interferon receptor beta chain-associated protein;
DE   AltName: Full=pRB-associated protein;
GN   Name=LIN9; Synonyms=BARA, TGS;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   LINES_HUMAN             Reviewed;         757 AA.
AC   Q8NG48; Q96FW2; Q9NVQ3;
DE   RecName: Full=Protein Lines homolog;
DE   AltName: Full=Protein Lines homolog 1;
DE   AltName: Full=Wnt-signaling molecule Lines homolog 1;
GN   Name=LINS; Synonyms=LINS1, WINS1;
//
ID   LIPA1_HUMAN             Reviewed;        1202 AA.
AC   Q13136; A6NLE3; Q13135; Q14567; Q8N4I2;
DE   RecName: Full=Liprin-alpha-1;
DE   AltName: Full=LAR-interacting protein 1;
DE            Short=LIP-1;
DE   AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1;
DE            Short=PTPRF-interacting protein alpha-1;
GN   Name=PPFIA1; Synonyms=LIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IMP:MGI.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IMP:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LIPA2_HUMAN             Reviewed;        1257 AA.
AC   O75334; B3KVT5; B3KXA0; B7Z2A6; B7Z3U9; B7Z663; B7ZKZ5; E7ERB8;
AC   E7ETG6; F8VP68; Q2M3G8;
DE   RecName: Full=Liprin-alpha-2;
DE   AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2;
DE            Short=PTPRF-interacting protein alpha-2;
GN   Name=PPFIA2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
//
ID   LIPA3_HUMAN             Reviewed;        1194 AA.
AC   O75145; A8K142; Q3MJA0; Q9H8B5; Q9UEW4;
DE   RecName: Full=Liprin-alpha-3;
DE   AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3;
DE            Short=PTPRF-interacting protein alpha-3;
GN   Name=PPFIA3; Synonyms=KIAA0654;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   LIPA4_HUMAN             Reviewed;        1185 AA.
AC   O75335; A2RUJ5; B1APN8; B1N949; B7ZM43; O94971;
DE   RecName: Full=Liprin-alpha-4;
DE   AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-4;
DE            Short=PTPRF-interacting protein alpha-4;
GN   Name=PPFIA4; Synonyms=KIAA0897;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   LIPB1_HUMAN             Reviewed;        1011 AA.
AC   Q86W92; O75336; Q86X70; Q9NY03; Q9ULJ0;
DE   RecName: Full=Liprin-beta-1;
DE   AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1;
DE            Short=PTPRF-interacting protein-binding protein 1;
DE   AltName: Full=hSGT2;
GN   Name=PPFIBP1; Synonyms=KIAA1230;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
//
ID   LIPB2_HUMAN             Reviewed;         876 AA.
AC   Q8ND30; B7Z433; E9PK77; O75337; Q8WW26;
DE   RecName: Full=Liprin-beta-2;
DE   AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2;
DE            Short=PTPRF-interacting protein-binding protein 2;
GN   Name=PPFIBP2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008907; F:integrase activity; IEA:InterPro.
//
ID   LIPC_HUMAN              Reviewed;         499 AA.
AC   P11150; A2RUB4; A8K9B6; O43571; P78529; Q99465;
DE   RecName: Full=Hepatic triacylglycerol lipase;
DE            Short=HL;
DE            Short=Hepatic lipase;
DE            EC=3.1.1.3;
DE   AltName: Full=Lipase member C;
DE   Flags: Precursor;
GN   Name=LIPC; Synonyms=HTGL;
DR   GO; GO:0034185; F:apolipoprotein binding; ISS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; ISS:BHF-UCL.
DR   GO; GO:0004620; F:phospholipase activity; TAS:BHF-UCL.
DR   GO; GO:0004806; F:triglyceride lipase activity; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0034382; P:chylomicron remnant clearance; TAS:BHF-UCL.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0034373; P:intermediate-density lipoprotein particle remodeling; TAS:BHF-UCL.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0034638; P:phosphatidylcholine catabolic process; TAS:BHF-UCL.
DR   GO; GO:0043691; P:reverse cholesterol transport; IC:BHF-UCL.
DR   GO; GO:0019433; P:triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:BHF-UCL.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
//
ID   LIPE_HUMAN              Reviewed;         500 AA.
AC   Q9Y5X9; B0LPG6; Q6P9C8; Q6UW82;
DE   RecName: Full=Endothelial lipase;
DE            EC=3.1.1.3;
DE   AltName: Full=Endothelial cell-derived lipase;
DE            Short=EDL;
DE            Short=EL;
DE   Flags: Precursor;
GN   Name=LIPG; ORFNames=UNQ387/PRO719;
DR   GuidetoPHARMACOLOGY; 2591; -.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004465; F:lipoprotein lipase activity; IEA:InterPro.
DR   GO; GO:0008970; F:phosphatidylcholine 1-acylhydrolase activity; IDA:MGI.
DR   GO; GO:0004620; F:phospholipase activity; IDA:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; IMP:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0009395; P:phospholipid catabolic process; NAS:BHF-UCL.
DR   GO; GO:0055091; P:phospholipid homeostasis; IMP:BHF-UCL.
DR   GO; GO:0032376; P:positive regulation of cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0010983; P:positive regulation of high-density lipoprotein particle clearance; IMP:BHF-UCL.
DR   GO; GO:0050746; P:regulation of lipoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0043691; P:reverse cholesterol transport; IMP:BHF-UCL.
//
ID   LIPG_HUMAN              Reviewed;         398 AA.
AC   P07098; B7Z723; F5H1P4; Q2M1P6; Q5VXI7; Q5VXI8; Q658L8;
DE   RecName: Full=Gastric triacylglycerol lipase;
DE            Short=GL;
DE            Short=Gastric lipase;
DE            EC=3.1.1.3;
DE   Flags: Precursor;
GN   Name=LIPF;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; NAS:UniProtKB.
DR   GO; GO:0016615; F:malate dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0004806; F:triglyceride lipase activity; TAS:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006108; P:malate metabolic process; IEA:Ensembl.
DR   GO; GO:0006641; P:triglyceride metabolic process; NAS:UniProtKB.
//
ID   LIPH_HUMAN              Reviewed;         451 AA.
AC   Q8WWY8; A2IBA7; Q8TEC7;
DE   RecName: Full=Lipase member H;
DE            Short=LIPH;
DE            EC=3.1.1.-;
DE   AltName: Full=LPD lipase-related protein;
DE   AltName: Full=Membrane-associated phosphatidic acid-selective phospholipase A1-alpha;
DE            Short=mPA-PLA1 alpha;
DE   AltName: Full=Phospholipase A1 member B;
DE   Flags: Precursor;
GN   Name=LIPH; Synonyms=LPDLR, MPAPLA1, PLA1B;
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0004620; F:phospholipase activity; IDA:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IDA:UniProtKB.
//
ID   LIPJ_HUMAN              Reviewed;         366 AA.
AC   Q5W064; A8MT98; Q0P671;
DE   RecName: Full=Lipase member J;
DE            EC=3.1.1.-;
DE   AltName: Full=Lipase-like abhydrolase domain-containing protein 1;
GN   Name=LIPJ; Synonyms=LIPL1;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   LIPK_HUMAN              Reviewed;         399 AA.
AC   Q5VXJ0; A7KIH8;
DE   RecName: Full=Lipase member K;
DE            EC=3.1.1.-;
DE   AltName: Full=Lipase-like abhydrolase domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=LIPK; Synonyms=LIPL2;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   LIPI_HUMAN              Reviewed;         460 AA.
AC   Q6XZB0; G1JSG3; G1JSG4; G1JSG5; G1JSG6; G1JSG7; G1JSG8; G1JSG9;
DE   RecName: Full=Lipase member I;
DE            Short=LIPI;
DE            EC=3.1.1.-;
DE   AltName: Full=Cancer/testis antigen 17;
DE            Short=CT17;
DE   AltName: Full=LPD lipase;
DE   AltName: Full=Membrane-associated phosphatidic acid-selective phospholipase A1-beta;
DE            Short=mPA-PLA1 beta;
DE   Flags: Precursor;
GN   Name=LIPI; Synonyms=LPDL; ORFNames=PRED5;
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0004620; F:phospholipase activity; IDA:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IDA:UniProtKB.
//
ID   LIPL_HUMAN              Reviewed;         475 AA.
AC   P06858; B2R5T9; Q16282; Q16283; Q96FC4;
DE   RecName: Full=Lipoprotein lipase;
DE            Short=LPL;
DE            EC=3.1.1.34;
DE   Flags: Precursor;
GN   Name=LPL; Synonyms=LIPD;
DR   GO; GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0004465; F:lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0004620; F:phospholipase activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0017129; F:triglyceride binding; IEA:Ensembl.
DR   GO; GO:0004806; F:triglyceride lipase activity; IDA:BHF-UCL.
DR   GO; GO:0034371; P:chylomicron remodeling; IC:BHF-UCL.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; IMP:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; IMP:BHF-UCL.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IEA:Ensembl.
DR   GO; GO:0019433; P:triglyceride catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070328; P:triglyceride homeostasis; IGI:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; ISS:BHF-UCL.
DR   GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:BHF-UCL.
//
ID   LIPM_HUMAN              Reviewed;         423 AA.
AC   Q5VYY2; A6PVS3; B5MCR3;
DE   RecName: Full=Lipase member M;
DE            EC=3.1.1.-;
DE   AltName: Full=Lipase-like abhydrolase domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=LIPM; Synonyms=LIPL3;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   LIPN_HUMAN              Reviewed;         398 AA.
AC   Q5VXI9; A7KIH9;
DE   RecName: Full=Lipase member N;
DE            EC=3.1.1.-;
DE   AltName: Full=Lipase-like abhydrolase domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=LIPN; Synonyms=LIPL4;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   LIPP_HUMAN              Reviewed;         465 AA.
AC   P16233; Q5VSQ2;
DE   RecName: Full=Pancreatic triacylglycerol lipase;
DE            Short=PL;
DE            Short=PTL;
DE            Short=Pancreatic lipase;
DE            EC=3.1.1.3;
DE   Flags: Precursor;
GN   Name=PNLIP;
DR   GuidetoPHARMACOLOGY; 2590; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004806; F:triglyceride lipase activity; TAS:ProtInc.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044241; P:lipid digestion; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LIPR1_HUMAN             Reviewed;         467 AA.
AC   P54315; Q68D83; Q68DR6; Q8TAU2; Q9BS82;
DE   RecName: Full=Inactive pancreatic lipase-related protein 1;
DE            Short=PL-RP1;
DE   Flags: Precursor;
GN   Name=PNLIPRP1; Synonyms=PLRP1;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0004806; F:triglyceride lipase activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   LIPR2_HUMAN             Reviewed;         469 AA.
AC   P54317; A8K627; Q6IB55;
DE   RecName: Full=Pancreatic lipase-related protein 2;
DE            Short=PL-RP2;
DE            EC=3.1.1.26;
DE            EC=3.1.1.3;
DE   AltName: Full=Galactolipase;
DE   Flags: Precursor;
GN   Name=PNLIPRP2; Synonyms=PLRP2;
DR   GO; GO:0047372; F:acylglycerol lipase activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0047714; F:galactolipase activity; IDA:UniProtKB.
DR   GO; GO:0004620; F:phospholipase activity; IDA:UniProtKB.
DR   GO; GO:0004806; F:triglyceride lipase activity; TAS:ProtInc.
DR   GO; GO:0019376; P:galactolipid catabolic process; IDA:UniProtKB.
DR   GO; GO:0044241; P:lipid digestion; TAS:Reactome.
DR   GO; GO:0009395; P:phospholipid catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; TAS:ProtInc.
//
ID   LIPR3_HUMAN             Reviewed;         467 AA.
AC   Q17RR3;
DE   RecName: Full=Pancreatic lipase-related protein 3;
DE            Short=PL-RP3;
DE            EC=3.1.1.3;
DE   Flags: Precursor;
GN   Name=PNLIPRP3;
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   LIPS_HUMAN              Reviewed;        1076 AA.
AC   Q05469; Q3LRT2; Q6NSL7;
DE   RecName: Full=Hormone-sensitive lipase;
DE            Short=HSL;
DE            EC=3.1.1.79;
GN   Name=LIPE;
DR   GuidetoPHARMACOLOGY; 2593; -.
DR   GO; GO:0033878; F:hormone-sensitive lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046340; P:diacylglycerol catabolic process; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; ISS:UniProtKB.
DR   GO; GO:0042758; P:long-chain fatty acid catabolic process; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   LIPT2_HUMAN             Reviewed;         231 AA.
AC   A6NK58;
DE   RecName: Full=Putative lipoyltransferase 2, mitochondrial;
DE            EC=2.3.1.181;
DE   AltName: Full=Lipoate-protein ligase B;
DE   AltName: Full=Lipoyl/octanoyl transferase;
DE   AltName: Full=Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase;
DE   Flags: Precursor;
GN   Name=LIPT2;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0033819; F:lipoyl(octanoyl) transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016415; F:octanoyltransferase activity; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
DR   GO; GO:0009107; P:lipoate biosynthetic process; IEA:InterPro.
//
ID   LIPT_HUMAN              Reviewed;         373 AA.
AC   Q9Y234; Q4ZFZ1;
DE   RecName: Full=Lipoyltransferase 1, mitochondrial;
DE            EC=2.3.1.-;
DE   AltName: Full=Lipoate biosynthesis protein;
DE   AltName: Full=Lipoate-protein ligase;
DE   AltName: Full=Lipoyl ligase;
DE   Flags: Precursor;
GN   Name=LIPT1;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0009249; P:protein lipoylation; IEA:InterPro.
//
ID   LIRA1_HUMAN             Reviewed;         489 AA.
AC   O75019; O75018; Q3MJA6;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 1;
DE   AltName: Full=CD85 antigen-like family member I;
DE   AltName: Full=Leukocyte immunoglobulin-like receptor 6;
DE            Short=LIR-6;
DE   AltName: CD_antigen=CD85i;
DE   Flags: Precursor;
GN   Name=LILRA1; Synonyms=LIR6;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LIRA2_HUMAN             Reviewed;         483 AA.
AC   Q8N149; O75020;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 2;
DE   AltName: Full=CD85 antigen-like family member H;
DE   AltName: Full=Immunoglobulin-like transcript 1;
DE            Short=ILT-1;
DE   AltName: Full=Leukocyte immunoglobulin-like receptor 7;
DE            Short=LIR-7;
DE   AltName: CD_antigen=CD85h;
DE   Flags: Precursor;
GN   Name=LILRA2; Synonyms=ILT1, LIR7;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LIRA3_HUMAN             Reviewed;         439 AA.
AC   Q8N6C8; J3KPM2; O15469; O15470; O75016; Q8N151; Q8N154; Q8NHJ1;
AC   Q8NHJ2; Q8NHJ3; Q8NHJ4;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 3;
DE   AltName: Full=CD85 antigen-like family member E;
DE   AltName: Full=Immunoglobulin-like transcript 6;
DE            Short=ILT-6;
DE   AltName: Full=Leukocyte immunoglobulin-like receptor 4;
DE            Short=LIR-4;
DE   AltName: Full=Monocyte inhibitory receptor HM43/HM31;
DE   AltName: CD_antigen=CD85e;
DE   Flags: Precursor;
GN   Name=LILRA3; Synonyms=ILT6, LIR4;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LIRA5_HUMAN             Reviewed;         299 AA.
AC   A6NI73; A6NHI3;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 5;
DE   AltName: Full=CD85 antigen-like family member F;
DE   AltName: Full=Immunoglobulin-like transcript 11;
DE            Short=ILT-11;
DE   AltName: Full=Leukocyte immunoglobulin-like receptor 9;
DE            Short=LIR-9;
DE   AltName: CD_antigen=CD85f;
DE   Flags: Precursor;
GN   Name=LILRA5; Synonyms=ILT11, LILRB7, LIR9;
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   LIRA4_HUMAN             Reviewed;         499 AA.
AC   P59901; Q32MC4;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 4;
DE   AltName: Full=CD85 antigen-like family member G;
DE   AltName: Full=Immunoglobulin-like transcript 7;
DE            Short=ILT-7;
DE   AltName: CD_antigen=CD85g;
DE   Flags: Precursor;
GN   Name=LILRA4; Synonyms=ILT7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   LIRA6_HUMAN             Reviewed;         481 AA.
AC   Q6PI73;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 6;
DE   AltName: Full=Immunoglobulin-like transcript 8;
DE            Short=ILT-8;
DE   AltName: Full=Leukocyte Ig-like receptor;
DE   Flags: Precursor;
GN   Name=LILRA6; Synonyms=ILT8;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   LIRB1_HUMAN             Reviewed;         650 AA.
AC   Q8NHL6; A2IXV4; A8MXT0; O75024; O75025; Q8NHJ9; Q8NHK0;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 1;
DE            Short=LIR-1;
DE            Short=Leukocyte immunoglobulin-like receptor 1;
DE   AltName: Full=CD85 antigen-like family member J;
DE   AltName: Full=Immunoglobulin-like transcript 2;
DE            Short=ILT-2;
DE   AltName: Full=Monocyte/macrophage immunoglobulin-like receptor 7;
DE            Short=MIR-7;
DE   AltName: CD_antigen=CD85j;
DE   Flags: Precursor;
GN   Name=LILRB1; Synonyms=ILT2, LIR1, MIR7;
DR   GO; GO:0030107; F:HLA-A specific inhibitory MHC class I receptor activity; IDA:UniProtKB.
DR   GO; GO:0030109; F:HLA-B specific inhibitory MHC class I receptor activity; IDA:UniProtKB.
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.
DR   GO; GO:0032393; F:MHC class I receptor activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0097028; P:dendritic cell differentiation; IEP:UniProtKB.
DR   GO; GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; IDA:UniProtKB.
DR   GO; GO:0002767; P:immune response-inhibiting cell surface receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0032609; P:interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0072643; P:interferon-gamma secretion; IDA:UniProtKB.
DR   GO; GO:0046636; P:negative regulation of alpha-beta T cell activation; IDA:UniProtKB.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:2001186; P:negative regulation of CD8-positive, alpha-beta T cell activation; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0002740; P:negative regulation of cytokine secretion involved in immune response; IDA:UniProtKB.
DR   GO; GO:2000669; P:negative regulation of dendritic cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001199; P:negative regulation of dendritic cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IDA:UniProtKB.
DR   GO; GO:0035548; P:negative regulation of interferon-beta secretion; IDA:UniProtKB.
DR   GO; GO:0045077; P:negative regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:2001180; P:negative regulation of interleukin-10 secretion; IDA:UniProtKB.
DR   GO; GO:2001183; P:negative regulation of interleukin-12 secretion; IDA:UniProtKB.
DR   GO; GO:0032945; P:negative regulation of mononuclear cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045953; P:negative regulation of natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:2001205; P:negative regulation of osteoclast development; IDA:UniProtKB.
DR   GO; GO:0014063; P:negative regulation of serotonin secretion; IDA:UniProtKB.
DR   GO; GO:2001189; P:negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IDA:UniProtKB.
DR   GO; GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:2001202; P:negative regulation of transforming growth factor-beta secretion; IDA:UniProtKB.
DR   GO; GO:0042536; P:negative regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045919; P:positive regulation of cytolysis; IDA:UniProtKB.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IDA:UniProtKB.
DR   GO; GO:2001193; P:positive regulation of gamma-delta T cell activation involved in immune response; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0031623; P:receptor internalization; TAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0002309; P:T cell proliferation involved in immune response; IDA:UniProtKB.
//
ID   LIRB2_HUMAN             Reviewed;         598 AA.
AC   Q8N423; O75017; Q8NHJ7; Q8NHJ8;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 2;
DE            Short=LIR-2;
DE            Short=Leukocyte immunoglobulin-like receptor 2;
DE   AltName: Full=CD85 antigen-like family member D;
DE   AltName: Full=Immunoglobulin-like transcript 4;
DE            Short=ILT-4;
DE   AltName: Full=Monocyte/macrophage immunoglobulin-like receptor 10;
DE            Short=MIR-10;
DE   AltName: CD_antigen=CD85d;
DE   Flags: Precursor;
GN   Name=LILRB2; Synonyms=ILT4, LIR2, MIR10;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0032396; F:inhibitory MHC class I receptor activity; IDA:BHF-UCL.
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.
DR   GO; GO:0023029; F:MHC class Ib protein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; IDA:UniProtKB.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0002767; P:immune response-inhibiting cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0002578; P:negative regulation of antigen processing and presentation; IDA:BHF-UCL.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; NAS:BHF-UCL.
DR   GO; GO:0045591; P:positive regulation of regulatory T cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0002666; P:positive regulation of T cell tolerance induction; IMP:BHF-UCL.
DR   GO; GO:2001198; P:regulation of dendritic cell differentiation; IC:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IDA:BHF-UCL.
//
ID   LIRB3_HUMAN             Reviewed;         631 AA.
AC   O75022; C9J1P3; C9JIP1; O15471; Q86U49;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 3;
DE            Short=LIR-3;
DE            Short=Leukocyte immunoglobulin-like receptor 3;
DE   AltName: Full=CD85 antigen-like family member A;
DE   AltName: Full=Immunoglobulin-like transcript 5;
DE            Short=ILT-5;
DE   AltName: Full=Monocyte inhibitory receptor HL9;
DE   AltName: CD_antigen=CD85a;
DE   Flags: Precursor;
GN   Name=LILRB3; Synonyms=ILT5, LIR3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
//
ID   LIRB4_HUMAN             Reviewed;         448 AA.
AC   Q8NHJ6; A8MVL8; O15468; O75021; Q6FGQ9; Q8N1C7; Q8NHL5;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 4;
DE   AltName: Full=CD85 antigen-like family member K;
DE   AltName: Full=Immunoglobulin-like transcript 3;
DE            Short=ILT-3;
DE   AltName: Full=Leukocyte immunoglobulin-like receptor 5;
DE            Short=LIR-5;
DE   AltName: Full=Monocyte inhibitory receptor HM18;
DE   AltName: CD_antigen=CD85k;
DE   Flags: Precursor;
GN   Name=LILRB4; Synonyms=ILT3, LIR5;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LIRB5_HUMAN             Reviewed;         590 AA.
AC   O75023; Q8N760;
DE   RecName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 5;
DE   AltName: Full=CD85 antigen-like family member C;
DE   AltName: Full=Leukocyte immunoglobulin-like receptor 8;
DE            Short=LIR-8;
DE   AltName: CD_antigen=CD85c;
DE   Flags: Precursor;
GN   Name=LILRB5; Synonyms=LIR8;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   LIS1_HUMAN              Reviewed;         410 AA.
AC   P43034; B2R7Q7; Q8WZ88; Q8WZ89;
DE   RecName: Full=Platelet-activating factor acetylhydrolase IB subunit alpha;
DE   AltName: Full=Lissencephaly-1 protein;
DE            Short=LIS-1;
DE   AltName: Full=PAF acetylhydrolase 45 kDa subunit;
DE            Short=PAF-AH 45 kDa subunit;
DE   AltName: Full=PAF-AH alpha;
DE            Short=PAFAH alpha;
GN   Name=PAFAH1B1; Synonyms=LIS1, MDCR, MDS, PAFAHA;
DR   GO; GO:0034452; F:dynactin binding; ISS:BHF-UCL.
DR   GO; GO:0045502; F:dynein binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; ISS:BHF-UCL.
DR   GO; GO:0008017; F:microtubule binding; ISS:BHF-UCL.
DR   GO; GO:0043274; F:phospholipase binding; ISS:BHF-UCL.
DR   GO; GO:0051219; F:phosphoprotein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0001675; P:acrosome assembly; ISS:BHF-UCL.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0008344; P:adult locomotory behavior; IMP:BHF-UCL.
DR   GO; GO:0001667; P:ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0048854; P:brain morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0021987; P:cerebral cortex development; IMP:BHF-UCL.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021540; P:corpus callosum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0051660; P:establishment of centrosome localization; IEA:Ensembl.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; ISS:BHF-UCL.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; ISS:BHF-UCL.
DR   GO; GO:0007611; P:learning or memory; ISS:BHF-UCL.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0031023; P:microtubule organizing center organization; IMP:UniProtKB.
DR   GO; GO:0007017; P:microtubule-based process; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0007405; P:neuroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IMP:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IMP:UniProtKB.
DR   GO; GO:0051081; P:nuclear envelope disassembly; IEA:Ensembl.
DR   GO; GO:0007097; P:nuclear migration; IEA:Ensembl.
DR   GO; GO:0036035; P:osteoclast development; IEA:Ensembl.
DR   GO; GO:0046469; P:platelet activating factor metabolic process; ISS:BHF-UCL.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0009306; P:protein secretion; IEA:Ensembl.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0008090; P:retrograde axon cargo transport; ISS:BHF-UCL.
DR   GO; GO:0017145; P:stem cell division; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0019226; P:transmission of nerve impulse; ISS:BHF-UCL.
DR   GO; GO:0047496; P:vesicle transport along microtubule; ISS:BHF-UCL.
//
ID   LITAF_HUMAN             Reviewed;         161 AA.
AC   Q99732; D3DUG1; G5E9K0; Q05DW0; Q9C0L6;
DE   RecName: Full=Lipopolysaccharide-induced tumor necrosis factor-alpha factor;
DE            Short=LPS-induced TNF-alpha factor;
DE   AltName: Full=Small integral membrane protein of lysosome/late endosome;
DE   AltName: Full=p53-induced gene 7 protein;
GN   Name=LITAF; Synonyms=PIG7, SIMPLE;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0001817; P:regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LITD1_HUMAN             Reviewed;         865 AA.
AC   Q5T7N2; Q8NDA1; Q9NUV8; Q9NV78;
DE   RecName: Full=LINE-1 type transposase domain-containing protein 1;
DE   AltName: Full=ES cell-associated protein 11;
GN   Name=L1TD1; Synonyms=ECAT11;
//
ID   LIX1L_HUMAN             Reviewed;         337 AA.
AC   Q8IVB5; Q6AI36;
DE   RecName: Full=LIX1-like protein;
GN   Name=LIX1L;
//
ID   LIX1_HUMAN              Reviewed;         282 AA.
AC   Q8N485; A8K4R9; Q8N7I2;
DE   RecName: Full=Protein limb expression 1 homolog;
GN   Name=LIX1; Synonyms=C5orf11;
//
ID   LKAM1_HUMAN             Reviewed;         194 AA.
AC   Q8TD35; Q8N419; Q8TD36;
DE   RecName: Full=Protein LKAAEAR1;
DE   AltName: Full=LKAAEAR motif-containing protein 1;
GN   Name=LKAAEAR1; Synonyms=C20orf201;
//
ID   LKHA4_HUMAN             Reviewed;         611 AA.
AC   P09960; B4DNQ9; F8VV40; Q6IAT6; Q9UCT7;
DE   RecName: Full=Leukotriene A-4 hydrolase;
DE            Short=LTA-4 hydrolase;
DE            EC=3.3.2.6;
DE   AltName: Full=Leukotriene A(4) hydrolase;
GN   Name=LTA4H; Synonyms=LTA4;
DR   GuidetoPHARMACOLOGY; 1395; -.
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0004301; F:epoxide hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0004463; F:leukotriene-A4 hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; NAS:ProtInc.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0043171; P:peptide catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LLPH_HUMAN              Reviewed;         129 AA.
AC   Q9BRT6; Q3B766;
DE   RecName: Full=Protein LLP homolog;
DE   AltName: Full=Protein LAPS18-like;
GN   Name=LLPH; Synonyms=C12orf31;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   LLR1_HUMAN              Reviewed;         414 AA.
AC   Q96L50; A5D6X3; B4DDE0; Q52M24; Q86SZ1; Q8N6H9;
DE   RecName: Full=Leucine-rich repeat protein 1;
DE   AltName: Full=4-1BB-mediated-signaling molecule;
DE   AltName: Full=4-1BBlrr;
DE   AltName: Full=LRR-repeat protein 1;
DE            Short=LRR-1;
DE   AltName: Full=Peptidylprolyl isomerase-like 5;
GN   Name=LRR1; Synonyms=PPIL5;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   LMA2L_HUMAN             Reviewed;         348 AA.
AC   Q9H0V9; B4DSH3; D3DXH6; Q53GV3; Q53S67; Q63HN6; Q8NBQ6; Q9BQ14;
DE   RecName: Full=VIP36-like protein;
DE   AltName: Full=Lectin mannose-binding 2-like;
DE            Short=LMAN2-like protein;
DE   Flags: Precursor;
GN   Name=LMAN2L; Synonyms=VIPL; ORFNames=PSEC0028, UNQ368/PRO704;
DR   GO; GO:0005537; F:mannose binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
//
ID   LMA1L_HUMAN             Reviewed;         526 AA.
AC   Q9HAT1; Q6UWN2;
DE   RecName: Full=Protein ERGIC-53-like;
DE   AltName: Full=ERGIC53-like protein;
DE   AltName: Full=Lectin mannose-binding 1-like;
DE            Short=LMAN1-like protein;
DE   Flags: Precursor;
GN   Name=LMAN1L; Synonyms=ERGL; ORFNames=UNQ2784/PRO7174;
//
ID   LMAN1_HUMAN             Reviewed;         510 AA.
AC   P49257; Q12895; Q8N5I7; Q9UQG1; Q9UQG2; Q9UQG3; Q9UQG4; Q9UQG5;
AC   Q9UQG6; Q9UQG7; Q9UQG8; Q9UQG9; Q9UQH0; Q9UQH1; Q9UQH2;
DE   RecName: Full=Protein ERGIC-53;
DE   AltName: Full=ER-Golgi intermediate compartment 53 kDa protein;
DE   AltName: Full=Gp58;
DE   AltName: Full=Intracellular mannose-specific lectin MR60;
DE   AltName: Full=Lectin mannose-binding 1;
DE   Flags: Precursor;
GN   Name=LMAN1; Synonyms=ERGIC53, F5F8D;
DR   GO; GO:0005537; F:mannose binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:Ensembl.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0010638; P:positive regulation of organelle organization; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   LMAN2_HUMAN             Reviewed;         356 AA.
AC   Q12907; Q53HH1;
DE   RecName: Full=Vesicular integral-membrane protein VIP36;
DE   AltName: Full=Glycoprotein GP36b;
DE   AltName: Full=Lectin mannose-binding 2;
DE   AltName: Full=Vesicular integral-membrane protein 36;
DE            Short=VIP36;
DE   Flags: Precursor;
GN   Name=LMAN2; Synonyms=C5orf8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   LMBD1_HUMAN             Reviewed;         540 AA.
AC   Q9NUN5; A8K204; E1P531; Q5VUN6; Q86Y70; Q96FW4; Q9BY56; Q9NZD6;
DE   RecName: Full=Probable lysosomal cobalamin transporter;
DE   AltName: Full=HDAg-L-interacting protein NESI;
DE   AltName: Full=LMBR1 domain-containing protein 1;
DE   AltName: Full=Nuclear export signal-interacting protein;
GN   Name=LMBRD1; Synonyms=C6orf209, NESI; ORFNames=BM-021, CD001, MSTP044;
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   LMBD2_HUMAN             Reviewed;         695 AA.
AC   Q68DH5; B3KRB6; Q9NTC7;
DE   RecName: Full=LMBR1 domain-containing protein 2;
GN   Name=LMBRD2;
//
ID   LMBL1_HUMAN             Reviewed;         752 AA.
AC   Q9Y468; B4DRC9; E1P5W7; Q5H8Y8; Q5H8Y9; Q8IUV7; Q9H1E6; Q9H1G5;
AC   Q9UG06; Q9UJB9; Q9Y4C9;
DE   RecName: Full=Lethal(3)malignant brain tumor-like protein 1;
DE            Short=H-l(3)mbt;
DE            Short=H-l(3)mbt protein;
DE            Short=L(3)mbt-like;
DE   AltName: Full=L(3)mbt protein homolog;
DE   AltName: Full=L3MBTL1;
GN   Name=L3MBTL1; Synonyms=KIAA0681, L3MBT, L3MBTL;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0031493; F:nucleosomal histone binding; IDA:UniProtKB.
DR   GO; GO:0031491; F:nucleosome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032093; F:SAM domain binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IDA:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IEP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; NAS:UniProtKB.
DR   GO; GO:0045652; P:regulation of megakaryocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMBL2_HUMAN             Reviewed;         705 AA.
AC   Q969R5; Q8TEN1; Q96SC4; Q9BQI2; Q9UGS4;
DE   RecName: Full=Lethal(3)malignant brain tumor-like protein 2;
DE            Short=H-l(3)mbt-like protein 2;
DE            Short=L(3)mbt-like protein 2;
GN   Name=L3MBTL2;
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMBL3_HUMAN             Reviewed;         780 AA.
AC   Q96JM7; Q4VXE1; Q5VUM9; Q6P9B5;
DE   RecName: Full=Lethal(3)malignant brain tumor-like protein 3;
DE            Short=H-l(3)mbt-like protein 3;
DE            Short=L(3)mbt-like protein 3;
DE   AltName: Full=MBT-1;
GN   Name=L3MBTL3; Synonyms=KIAA1798, MBT1;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMBL4_HUMAN             Reviewed;         623 AA.
AC   Q8NA19; A8MTL8; Q8IXS3;
DE   RecName: Full=Lethal(3)malignant brain tumor-like protein 4;
DE            Short=H-l(3)mbt-like protein 4;
DE            Short=L(3)mbt-like protein 4;
GN   Name=L3MBTL4;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMBR1_HUMAN             Reviewed;         490 AA.
AC   Q8WVP7; A4D242; Q8N3E3; Q96QZ5; Q9H5N0; Q9HAG9; Q9UDN5; Q9Y6U2;
DE   RecName: Full=Limb region 1 protein homolog;
DE   AltName: Full=Differentiation-related gene 14 protein;
GN   Name=LMBR1; Synonyms=C7orf2, DIF14;
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
//
ID   LMBRL_HUMAN             Reviewed;         489 AA.
AC   Q6UX01; Q969J4; Q96BY8; Q96HN8; Q9NT09; Q9NVE1; Q9NVU9; Q9ULP6;
DE   RecName: Full=Protein LMBR1L;
DE   AltName: Full=Limb region 1 protein homolog-like;
DE   AltName: Full=Lipocalin-1-interacting membrane receptor;
DE            Short=Lipocalin-interacting membrane receptor;
GN   Name=LMBR1L; Synonyms=KIAA1174, LIMR; ORFNames=UNQ458/PRO783;
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
//
ID   LMCD1_HUMAN             Reviewed;         365 AA.
AC   Q9NZU5; B4DG80;
DE   RecName: Full=LIM and cysteine-rich domains protein 1;
DE   AltName: Full=Dyxin;
GN   Name=LMCD1;
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0070886; P:positive regulation of calcineurin-NFAT signaling cascade; IMP:UniProtKB.
DR   GO; GO:0010611; P:regulation of cardiac muscle hypertrophy; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMF1_HUMAN              Reviewed;         567 AA.
AC   Q96S06; Q68CJ3; Q96FJ4; Q9H6G4; Q9H9K7;
DE   RecName: Full=Lipase maturation factor 1;
DE   AltName: Full=Transmembrane protein 112;
GN   Name=LMF1; Synonyms=C16orf26, TMEM112; ORFNames=HMFN1876, JFP11;
DR   GO; GO:0034382; P:chylomicron remnant clearance; IEA:Ensembl.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IEA:Ensembl.
DR   GO; GO:0033578; P:protein glycosylation in Golgi; IEA:Ensembl.
DR   GO; GO:0051604; P:protein maturation; IEA:Ensembl.
DR   GO; GO:0009306; P:protein secretion; IEA:Ensembl.
DR   GO; GO:0090181; P:regulation of cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0090207; P:regulation of triglyceride metabolic process; IEA:Ensembl.
//
ID   LMF2_HUMAN              Reviewed;         707 AA.
AC   Q9BU23; A6NEZ0; Q13392; Q6ZNR2; Q8WU74; Q96C62;
DE   RecName: Full=Lipase maturation factor 2;
DE   AltName: Full=Transmembrane protein 112B;
DE   AltName: Full=Transmembrane protein 153;
GN   Name=LMF2; Synonyms=TMEM112B, TMEM153;
//
ID   LMIP_HUMAN              Reviewed;         173 AA.
AC   P55344; Q6B083; Q9BXD0; Q9HAR5;
DE   RecName: Full=Lens fiber membrane intrinsic protein;
DE   AltName: Full=MP18;
DE   AltName: Full=MP19;
DE   AltName: Full=MP20;
GN   Name=LIM2;
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0007043; P:cell-cell junction assembly; NAS:UniProtKB.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
//
ID   LMLN_HUMAN              Reviewed;         655 AA.
AC   Q96KR4; B3LDG9; B3LDH0; C9J796; F8WB28; Q96KR5;
DE   RecName: Full=Leishmanolysin-like peptidase;
DE            EC=3.4.24.-;
DE   AltName: Full=Invadolysin;
GN   Name=LMLN;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   LMNA_HUMAN              Reviewed;         664 AA.
AC   P02545; B4DI32; D3DVB0; D6RAQ3; E7EUI9; P02546; Q5I6Y4; Q5I6Y6;
AC   Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2;
DE   RecName: Full=Prelamin-A/C;
DE   Contains:
DE     RecName: Full=Lamin-A/C;
DE     AltName: Full=70 kDa lamin;
DE     AltName: Full=Renal carcinoma antigen NY-REN-32;
DE   Flags: Precursor;
GN   Name=LMNA; Synonyms=LMN1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; ISS:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; IMP:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0090343; P:positive regulation of cell aging; IDA:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; ISS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0035105; P:sterol regulatory element binding protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
//
ID   LMNB1_HUMAN             Reviewed;         586 AA.
AC   P20700; B2R6J6; Q3SYN7; Q96EI6;
DE   RecName: Full=Lamin-B1;
DE   Flags: Precursor;
GN   Name=LMNB1; Synonyms=LMN2, LMNB;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
//
ID   LMNB2_HUMAN             Reviewed;         600 AA.
AC   Q03252; O75292; Q14734; Q96DF6;
DE   RecName: Full=Lamin-B2;
DE   Flags: Precursor;
GN   Name=LMNB2; Synonyms=LMN2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   LMO3_HUMAN              Reviewed;         145 AA.
AC   Q8TAP4; B4DG90; B4DH35; Q58A66; Q58A67; Q8N974; Q9UDD5;
DE   RecName: Full=LIM domain only protein 3;
DE            Short=LMO-3;
DE   AltName: Full=Neuronal-specific transcription factor DAT1;
DE   AltName: Full=Rhombotin-3;
GN   Name=LMO3; Synonyms=RBTN3, RBTNL2, RHOM3;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMO4_HUMAN              Reviewed;         165 AA.
AC   P61968; D3DT23; O00158; O88894;
DE   RecName: Full=LIM domain transcription factor LMO4;
DE   AltName: Full=Breast tumor autoantigen;
DE   AltName: Full=LIM domain only protein 4;
DE            Short=LMO-4;
GN   Name=LMO4;
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050865; P:regulation of cell activation; IEA:Ensembl.
DR   GO; GO:0042659; P:regulation of cell fate specification; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0021514; P:ventral spinal cord interneuron differentiation; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   LMO7D_HUMAN             Reviewed;         122 AA.
AC   F2Z398; Q8NAG9;
DE   RecName: Full=LMO7 downstream neighbor protein;
GN   Name=LMO7DN; Synonyms=C13orf45;
//
ID   LMO7_HUMAN              Reviewed;        1683 AA.
AC   Q8WWI1; O15462; O95346; Q5TBK6; Q9UKC1; Q9UQM5; Q9Y6A7;
DE   RecName: Full=LIM domain only protein 7;
DE            Short=LMO-7;
DE   AltName: Full=F-box only protein 20;
DE   AltName: Full=LOMP;
GN   Name=LMO7; Synonyms=FBX20, FBXO20, KIAA0858;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
//
ID   LMOD1_HUMAN             Reviewed;         600 AA.
AC   P29536; B1APV6; C4AMB1; Q68EN2;
DE   RecName: Full=Leiomodin-1;
DE   AltName: Full=64 kDa autoantigen 1D;
DE   AltName: Full=64 kDa autoantigen 1D3;
DE   AltName: Full=64 kDa autoantigen D1;
DE   AltName: Full=Leiomodin, muscle form;
DE   AltName: Full=Smooth muscle leiomodin;
DE            Short=SM-Lmod;
DE   AltName: Full=Thyroid-associated ophthalmopathy autoantigen;
GN   Name=LMOD1;
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
//
ID   LMOD2_HUMAN             Reviewed;         547 AA.
AC   Q6P5Q4; A4D0W9; A4D0Y2; Q8WVJ8;
DE   RecName: Full=Leiomodin-2;
DE   AltName: Full=Cardiac leiomodin;
DE            Short=C-LMOD;
GN   Name=LMOD2;
//
ID   LMOD3_HUMAN             Reviewed;         560 AA.
AC   Q0VAK6; B4DT85; Q0JTT2; Q5JPG6; Q8IUK4; Q96LS4;
DE   RecName: Full=Leiomodin-3;
DE   AltName: Full=Leiomodin, fetal form;
GN   Name=LMOD3;
//
ID   LMTK1_HUMAN             Reviewed;        1374 AA.
AC   Q6ZMQ8; O75136; Q6ZN31; Q86X28;
DE   RecName: Full=Serine/threonine-protein kinase LMTK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Apoptosis-associated tyrosine kinase;
DE            Short=AATYK;
DE   AltName: Full=Brain apoptosis-associated tyrosine kinase;
DE   AltName: Full=CDK5-binding protein;
DE   AltName: Full=Lemur tyrosine kinase 1;
DE   AltName: Full=p35-binding protein;
DE            Short=p35BP;
GN   Name=AATK; Synonyms=AATYK, KIAA0641, LMR1, LMTK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0038083; P:peptidyl-tyrosine autophosphorylation; IEA:Ensembl.
DR   GO; GO:0032482; P:Rab protein signal transduction; IEA:Ensembl.
//
ID   LMTK2_HUMAN             Reviewed;        1503 AA.
AC   Q8IWU2; A4D272; Q75MG7; Q9UPS3;
DE   RecName: Full=Serine/threonine-protein kinase LMTK2;
DE            EC=2.7.11.1;
DE   AltName: Full=Apoptosis-associated tyrosine kinase 2;
DE   AltName: Full=Brain-enriched kinase;
DE            Short=hBREK;
DE   AltName: Full=CDK5/p35-regulated kinase;
DE            Short=CPRK;
DE   AltName: Full=Kinase/phosphatase/inhibitor 2;
DE   AltName: Full=Lemur tyrosine kinase 2;
DE   AltName: Full=Serine/threonine-protein kinase KPI-2;
GN   Name=LMTK2; Synonyms=AATYK2, BREK, KIAA1079, KPI2, LMR2;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0070853; F:myosin VI binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; IMP:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001881; P:receptor recycling; IMP:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; IMP:UniProtKB.
//
ID   LMTK3_HUMAN             Reviewed;        1460 AA.
AC   Q96Q04; Q4G0U1;
DE   RecName: Full=Serine/threonine-protein kinase LMTK3;
DE            EC=2.7.11.1;
DE   AltName: Full=Lemur tyrosine kinase 3;
DE   Flags: Precursor;
GN   Name=LMTK3; Synonyms=KIAA1883, TYKLM3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   LMX1A_HUMAN             Reviewed;         382 AA.
AC   Q8TE12; B3KXP6; Q0VDB5; Q5VWG4; Q8TE11;
DE   RecName: Full=LIM homeobox transcription factor 1-alpha;
DE   AltName: Full=LIM/homeobox protein 1.1;
DE            Short=LMX-1.1;
DE   AltName: Full=LIM/homeobox protein LMX1A;
GN   Name=LMX1A;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LMX1B_HUMAN             Reviewed;         402 AA.
AC   O60663; F8W7W6; O75463; Q5JU95; Q6ISC9;
DE   RecName: Full=LIM homeobox transcription factor 1-beta;
DE   AltName: Full=LIM/homeobox protein 1.2;
DE            Short=LMX-1.2;
DE   AltName: Full=LIM/homeobox protein LMX1B;
GN   Name=LMX1B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0021587; P:cerebellum morphogenesis; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; NAS:UniProtKB.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0002930; P:trabecular meshwork development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LN28A_HUMAN             Reviewed;         209 AA.
AC   Q9H9Z2;
DE   RecName: Full=Protein lin-28 homolog A;
DE            Short=Lin-28A;
DE   AltName: Full=Zinc finger CCHC domain-containing protein 1;
GN   Name=LIN28A; Synonyms=CSDD1, LIN28, ZCCHC1;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0035198; F:miRNA binding; IEA:Ensembl.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0010587; P:miRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0045686; P:negative regulation of glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0031054; P:pre-miRNA processing; IMP:UniProtKB.
DR   GO; GO:0060964; P:regulation of gene silencing by miRNA; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031123; P:RNA 3'-end processing; IMP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IMP:UniProtKB.
//
ID   LN28B_HUMAN             Reviewed;         250 AA.
AC   Q6ZN17; A1L165; B2RPN6; Q5TCM4;
DE   RecName: Full=Protein lin-28 homolog B;
DE            Short=Lin-28B;
GN   Name=LIN28B; Synonyms=CSDD2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010587; P:miRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0031054; P:pre-miRNA processing; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0031123; P:RNA 3'-end processing; IMP:UniProtKB.
//
ID   LNP1_HUMAN              Reviewed;         178 AA.
AC   A1A4G5; B7ZLT3;
DE   RecName: Full=Leukemia NUP98 fusion partner 1;
GN   Name=LNP1; Synonyms=NP3;
//
ID   LNP_HUMAN               Reviewed;         428 AA.
AC   Q9C0E8; B7ZLA8; Q2M2V8; Q2YD99; Q658W8; Q8N5V9; Q96MS5;
DE   RecName: Full=Protein lunapark;
GN   Name=LNP; Synonyms=KIAA1715;
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060173; P:limb development; NAS:UniProtKB.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; IEA:Ensembl.
//
ID   LNX1_HUMAN              Reviewed;         728 AA.
AC   Q8TBB1; Q4W5K7; Q8N4C2; Q96MJ7; Q9BY20;
DE   RecName: Full=E3 ubiquitin-protein ligase LNX;
DE            EC=6.3.2.-;
DE   AltName: Full=Ligand of Numb-protein X 1;
DE   AltName: Full=Numb-binding protein 1;
DE   AltName: Full=PDZ domain-containing RING finger protein 2;
GN   Name=LNX1; Synonyms=LNX, PDZRN2; ORFNames=UNQ574/PRO1136;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   LNX2_HUMAN              Reviewed;         690 AA.
AC   Q8N448; Q5W0P0; Q6ZMH2; Q96SH4;
DE   RecName: Full=Ligand of Numb protein X 2;
DE   AltName: Full=Numb-binding protein 2;
DE   AltName: Full=PDZ domain-containing RING finger protein 1;
GN   Name=LNX2; Synonyms=PDZRN1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
//
ID   LONF1_HUMAN             Reviewed;         773 AA.
AC   Q17RB8; B4DM29; B4DU84; Q8TEA0; Q9BSV1;
DE   RecName: Full=LON peptidase N-terminal domain and RING finger protein 1;
DE   AltName: Full=RING finger protein 191;
GN   Name=LONRF1; Synonyms=RNF191;
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   LONF2_HUMAN             Reviewed;         754 AA.
AC   Q1L5Z9; B9A006; Q6ZSR4;
DE   RecName: Full=LON peptidase N-terminal domain and RING finger protein 2;
DE   AltName: Full=Neuroblastoma apoptosis-related protease;
DE   AltName: Full=RING finger protein 192;
GN   Name=LONRF2; Synonyms=RNF192;
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   LONF3_HUMAN             Reviewed;         759 AA.
AC   Q496Y0; Q5JPN6; Q8NB00; Q9H647;
DE   RecName: Full=LON peptidase N-terminal domain and RING finger protein 3;
DE   AltName: Full=RING finger protein 127;
GN   Name=LONRF3; Synonyms=RNF127;
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   LONM_HUMAN              Reviewed;         959 AA.
AC   P36776; D6W635; E5KMH8; P36777; Q8N8K8; Q9UQ95;
DE   RecName: Full=Lon protease homolog, mitochondrial;
DE            EC=3.4.21.-;
DE   AltName: Full=LONHs;
DE   AltName: Full=Lon protease-like protein;
DE            Short=LONP;
DE   AltName: Full=Mitochondrial ATP-dependent protease Lon;
DE   AltName: Full=Serine protease 15;
DE   Flags: Precursor;
GN   Name=LONP1; Synonyms=PRSS15;
DR   GO; GO:0043531; F:ADP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070182; F:DNA polymerase binding; IPI:UniProtKB.
DR   GO; GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.
DR   GO; GO:0070362; F:mitochondrial heavy strand promoter anti-sense binding; IDA:UniProtKB.
DR   GO; GO:0070361; F:mitochondrial light strand promoter anti-sense binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032042; P:mitochondrial DNA metabolic process; NAS:UniProtKB.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; NAS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:0070407; P:oxidation-dependent protein catabolic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0090296; P:regulation of mitochondrial DNA replication; IEA:UniProtKB-HAMAP.
DR   GO; GO:0010044; P:response to aluminum ion; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
//
ID   LONP2_HUMAN             Reviewed;         852 AA.
AC   Q86WA8; Q0D2H6; Q8N3B9; Q8NCE9; Q96K43;
DE   RecName: Full=Lon protease homolog 2, peroxisomal;
DE            EC=3.4.21.-;
DE   AltName: Full=Lon protease-like protein 2;
DE            Short=Lon protease 2;
DE   AltName: Full=Peroxisomal Lon protease;
GN   Name=LONP2; Synonyms=LONP;
DR   GO; GO:0005524; F:ATP binding; IBA:RefGenome.
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:RefGenome.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IBA:RefGenome.
DR   GO; GO:0007031; P:peroxisome organization; NAS:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006625; P:protein targeting to peroxisome; NAS:UniProtKB.
DR   GO; GO:0031998; P:regulation of fatty acid beta-oxidation; IMP:UniProtKB.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006465; P:signal peptide processing; IMP:UniProtKB.
//
ID   LORF1_HUMAN             Reviewed;         338 AA.
AC   Q9UN81; Q15605;
DE   RecName: Full=LINE-1 retrotransposable element ORF1 protein;
DE            Short=L1ORF1p;
DE   AltName: Full=LINE retrotransposable element 1;
DE   AltName: Full=LINE1 retrotransposable element 1;
GN   Name=L1RE1; Synonyms=LRE1;
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0032197; P:transposition, RNA-mediated; IMP:UniProtKB.
//
ID   LORF2_HUMAN             Reviewed;        1275 AA.
AC   O00370;
DE   RecName: Full=LINE-1 retrotransposable element ORF2 protein;
DE            Short=ORF2p;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Endonuclease;
DE              EC=3.1.21.-;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0009036; F:Type II site-specific deoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:UniProtKB.
DR   GO; GO:0032199; P:reverse transcription involved in RNA-mediated transposition; IDA:UniProtKB.
DR   GO; GO:0032197; P:transposition, RNA-mediated; IMP:UniProtKB.
//
ID   LORI_HUMAN              Reviewed;         312 AA.
AC   P23490; Q5T869; Q5XKF8;
DE   RecName: Full=Loricrin;
GN   Name=LOR; Synonyms=LRN;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
//
ID   LOX15_HUMAN             Reviewed;         662 AA.
AC   P16050; A8K2P4; Q8N6R7; Q99657;
DE   RecName: Full=Arachidonate 15-lipoxygenase;
DE            Short=15-LOX;
DE            Short=15-LOX-1;
DE            EC=1.13.11.33;
DE   AltName: Full=12/15-lipoxygenase;
DE   AltName: Full=Arachidonate 12-lipoxygenase, leukocyte-type;
DE            Short=12-LOX;
DE            EC=1.13.11.31;
DE   AltName: Full=Arachidonate omega-6 lipoxygenase;
GN   Name=ALOX15; Synonyms=LOG15;
DR   GO; GO:0004052; F:arachidonate 12-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0050473; F:arachidonate 15-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0097260; F:eoxin A4 synthase activity; TAS:Reactome.
DR   GO; GO:0005506; F:iron ion binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043277; P:apoptotic cell clearance; ISS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; ISS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0035963; P:cellular response to interleukin-13; IMP:UniProtKB.
DR   GO; GO:0051122; P:hepoxilin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:2001303; P:lipoxin A4 biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0019372; P:lipoxygenase pathway; IDA:UniProtKB.
DR   GO; GO:0002820; P:negative regulation of adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0001503; P:ossification; ISS:UniProtKB.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:1901074; P:regulation of engulfment of apoptotic cell; ISS:UniProtKB.
DR   GO; GO:0035358; P:regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
//
ID   LOX12_HUMAN             Reviewed;         663 AA.
AC   P18054; O95569; Q6ISF8; Q9UQM4;
DE   RecName: Full=Arachidonate 12-lipoxygenase, 12S-type;
DE            Short=12S-LOX;
DE            Short=12S-lipoxygenase;
DE            EC=1.13.11.31;
DE   AltName: Full=Lipoxin synthase 12-LO;
DE            EC=3.3.2.-;
DE   AltName: Full=Platelet-type lipoxygenase 12;
GN   Name=ALOX12; Synonyms=12LO, LOG12;
DR   GO; GO:0004052; F:arachidonate 12-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0051120; F:hepoxilin A3 synthase activity; TAS:Reactome.
DR   GO; GO:0047977; F:hepoxilin-epoxide hydrolase activity; ISS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016165; F:linoleate 13S-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; IMP:UniProtKB.
DR   GO; GO:0071396; P:cellular response to lipid; IEA:Ensembl.
DR   GO; GO:0061436; P:establishment of skin barrier; ISS:UniProtKB.
DR   GO; GO:0019395; P:fatty acid oxidation; IMP:UniProtKB.
DR   GO; GO:0051122; P:hepoxilin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051121; P:hepoxilin metabolic process; TAS:Reactome.
DR   GO; GO:1901751; P:leukotriene A4 metabolic process; IDA:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:2001303; P:lipoxin A4 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2001306; P:lipoxin B4 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2001300; P:lipoxin metabolic process; TAS:Reactome.
DR   GO; GO:0019372; P:lipoxygenase pathway; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010656; P:negative regulation of muscle cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042554; P:superoxide anion generation; NAS:UniProtKB.
//
ID   LOX5_HUMAN              Reviewed;         674 AA.
AC   P09917; B7ZLS0; E5FPY5; E5FPY7; E5FPY8; Q5JQ14;
DE   RecName: Full=Arachidonate 5-lipoxygenase;
DE            Short=5-LO;
DE            Short=5-lipoxygenase;
DE            EC=1.13.11.34;
GN   Name=ALOX5; Synonyms=LOG5;
DR   GuidetoPHARMACOLOGY; 1385; -.
DR   GO; GO:0004051; F:arachidonate 5-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0002540; P:leukotriene production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:2001300; P:lipoxin metabolic process; TAS:Reactome.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LOXE3_HUMAN             Reviewed;         711 AA.
AC   Q9BYJ1; B2R981; B7Z3W0; Q3ZB74; Q9H4F2; Q9HC22;
DE   RecName: Full=Hydroperoxide isomerase ALOXE3;
DE            EC=5.4.4.-;
DE   AltName: Full=Epidermis-type lipoxygenase 3;
DE            Short=Epidermal LOX-3;
DE            Short=e-LOX-3;
DE            Short=eLOX-3;
DE            EC=1.13.11.-;
GN   Name=ALOXE3;
DR   GO; GO:0051120; F:hepoxilin A3 synthase activity; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0046513; P:ceramide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0061436; P:establishment of skin barrier; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0051122; P:hepoxilin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0019372; P:lipoxygenase pathway; IDA:UniProtKB.
DR   GO; GO:0035357; P:peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IDA:UniProtKB.
//
ID   LOXH1_HUMAN             Reviewed;        1947 AA.
AC   Q8IVV2; B7WNN3; B7WNT1; B7WPI9; Q6ZRY7; Q86WW9; Q96DL7;
DE   RecName: Full=Lipoxygenase homology domain-containing protein 1;
GN   Name=LOXHD1;
DR   GO; GO:0005262; F:calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GOC.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
//
ID   LOXL1_HUMAN             Reviewed;         574 AA.
AC   Q08397; Q6NUL3; Q96BW7;
DE   RecName: Full=Lysyl oxidase homolog 1;
DE            EC=1.4.3.-;
DE   AltName: Full=Lysyl oxidase-like protein 1;
DE            Short=LOL;
DE   Flags: Precursor;
GN   Name=LOXL1; Synonyms=LOXL;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016641; F:oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0018277; P:protein deamination; TAS:UniProtKB.
//
ID   LOXL2_HUMAN             Reviewed;         774 AA.
AC   Q9Y4K0; B2R5Q0; Q53HV3; Q9BW70; Q9Y5Y8;
DE   RecName: Full=Lysyl oxidase homolog 2;
DE            EC=1.4.3.13;
DE   AltName: Full=Lysyl oxidase-like protein 2;
DE   AltName: Full=Lysyl oxidase-related protein 2;
DE   AltName: Full=Lysyl oxidase-related protein WS9-14;
DE   Flags: Precursor;
GN   Name=LOXL2;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0070492; F:oligosaccharide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004720; F:protein-lysine 6-oxidase activity; IDA:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:UniProtKB.
DR   GO; GO:0030199; P:collagen fibril organization; IMP:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0016570; P:histone modification; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0018277; P:protein deamination; IDA:UniProtKB.
DR   GO; GO:0046688; P:response to copper ion; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; ISS:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LOXL3_HUMAN             Reviewed;         753 AA.
AC   P58215; D6W5J1; Q2EHP2; Q6IPL7; Q96RS1;
DE   RecName: Full=Lysyl oxidase homolog 3;
DE            EC=1.4.3.-;
DE   AltName: Full=Lysyl oxidase-like protein 3;
DE   Flags: Precursor;
GN   Name=LOXL3; Synonyms=LOXL;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016641; F:oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004720; F:protein-lysine 6-oxidase activity; NAS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   LOXL4_HUMAN             Reviewed;         756 AA.
AC   Q96JB6; Q5W0B3; Q96DY1; Q96PC0; Q9H6T5;
DE   RecName: Full=Lysyl oxidase homolog 4;
DE            EC=1.4.3.-;
DE   AltName: Full=Lysyl oxidase-like protein 4;
DE   AltName: Full=Lysyl oxidase-related protein C;
DE   Flags: Precursor;
GN   Name=LOXL4; Synonyms=LOXC;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004720; F:protein-lysine 6-oxidase activity; IEA:Ensembl.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
//
ID   LPAL2_HUMAN             Reviewed;         132 AA.
AC   Q16609; E1P5B4;
DE   RecName: Full=Putative apolipoprotein(a)-like protein 2;
DE            Short=Apo(a)-like protein 2;
DE            Short=Lp(a)-liker protein 2;
DE   AltName: Full=Apolipoprotein a-related gene C protein;
DE            Short=Apo(a)rg-C;
DE   Flags: Precursor;
GN   Name=LPAL2; Synonyms=APOARGC;
//
ID   LPAR1_HUMAN             Reviewed;         364 AA.
AC   Q92633; O00656; O00722; P78351;
DE   RecName: Full=Lysophosphatidic acid receptor 1;
DE            Short=LPA receptor 1;
DE            Short=LPA-1;
DE   AltName: Full=Lysophosphatidic acid receptor Edg-2;
GN   Name=LPAR1; Synonyms=EDG2, LPA1;
DR   GuidetoPHARMACOLOGY; 272; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0070915; F:lysophosphatidic acid receptor activity; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0032060; P:bleb assembly; IEA:Ensembl.
DR   GO; GO:0071453; P:cellular response to oxygen levels; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0071673; P:positive regulation of smooth muscle cell chemotaxis; IEA:Ensembl.
//
ID   LPAR2_HUMAN             Reviewed;         351 AA.
AC   Q9HBW0; O00543; O43431;
DE   RecName: Full=Lysophosphatidic acid receptor 2;
DE            Short=LPA receptor 2;
DE            Short=LPA-2;
DE   AltName: Full=Lysophosphatidic acid receptor Edg-4;
GN   Name=LPAR2; Synonyms=EDG4, LPA2;
DR   GuidetoPHARMACOLOGY; 273; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0070915; F:lysophosphatidic acid receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IEA:Ensembl.
//
ID   LPAR3_HUMAN             Reviewed;         353 AA.
AC   Q9UBY5; A0AVA3;
DE   RecName: Full=Lysophosphatidic acid receptor 3;
DE            Short=LPA receptor 3;
DE            Short=LPA-3;
DE   AltName: Full=Lysophosphatidic acid receptor Edg-7;
GN   Name=LPAR3; Synonyms=EDG7, LPA3;
DR   GuidetoPHARMACOLOGY; 274; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0070915; F:lysophosphatidic acid receptor activity; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0032060; P:bleb assembly; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0048672; P:positive regulation of collateral sprouting; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   LPAR4_HUMAN             Reviewed;         370 AA.
AC   Q99677; B2RAC7; O15132; Q502U9; Q6NSP5;
DE   RecName: Full=Lysophosphatidic acid receptor 4;
DE            Short=LPA receptor 4;
DE            Short=LPA-4;
DE   AltName: Full=G-protein coupled receptor 23;
DE   AltName: Full=P2Y purinoceptor 9;
DE            Short=P2Y9;
DE   AltName: Full=P2Y5-like receptor;
DE   AltName: Full=Purinergic receptor 9;
GN   Name=LPAR4; Synonyms=GPR23, LPA4, P2RY9;
DR   GuidetoPHARMACOLOGY; 94; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   LPAR5_HUMAN             Reviewed;         372 AA.
AC   Q9H1C0;
DE   RecName: Full=Lysophosphatidic acid receptor 5;
DE            Short=LPA receptor 5;
DE            Short=LPA-5;
DE   AltName: Full=G-protein coupled receptor 92;
DE   AltName: Full=G-protein coupled receptor 93;
GN   Name=LPAR5; Synonyms=GPR92, GPR93;
DR   GuidetoPHARMACOLOGY; 124; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   LPAR6_HUMAN             Reviewed;         344 AA.
AC   P43657; A4FTW9; B3KVF2; F2YGU4; O15133; Q3KPF5; Q53FA0; Q5VW44;
AC   Q7Z3S0; Q7Z3S6;
DE   RecName: Full=Lysophosphatidic acid receptor 6;
DE            Short=LPA receptor 6;
DE            Short=LPA-6;
DE   AltName: Full=Oleoyl-L-alpha-lysophosphatidic acid receptor;
DE   AltName: Full=P2Y purinoceptor 5;
DE            Short=P2Y5;
DE   AltName: Full=Purinergic receptor 5;
DE   AltName: Full=RB intron encoded G-protein coupled receptor;
GN   Name=LPAR6; Synonyms=P2RY5;
DR   GuidetoPHARMACOLOGY; 163; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   LPCT4_HUMAN             Reviewed;         524 AA.
AC   Q643R3; A8K2K8; O43412; Q7Z4P4; Q8IUL7; Q8TB38;
DE   RecName: Full=Lysophospholipid acyltransferase LPCAT4;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 7;
DE            Short=1-AGP acyltransferase 7;
DE            Short=1-AGPAT 7;
DE   AltName: Full=1-acylglycerophosphocholine O-acyltransferase;
DE            EC=2.3.1.23;
DE   AltName: Full=1-acylglycerophosphoserine O-acyltransferase;
DE            EC=2.3.1.n6;
DE   AltName: Full=1-alkenylglycerophosphoethanolamine O-acyltransferase;
DE            EC=2.3.1.121;
DE   AltName: Full=1-alkylglycerophosphocholine O-acetyltransferase;
DE            EC=2.3.1.67;
DE   AltName: Full=Acyltransferase-like 3;
DE   AltName: Full=Lysophosphatidylcholine acyltransferase 4;
DE   AltName: Full=Lysophosphatidylethanolamine acyltransferase 2;
DE            EC=2.3.1.n7;
DE   AltName: Full=Plasmalogen synthase;
GN   Name=LPCAT4; Synonyms=AGPAT7, AYTL3, LPEAT2;
DR   GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047166; F:1-alkenylglycerophosphoethanolamine O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047192; F:1-alkylglycerophosphocholine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0071617; F:lysophospholipid acyltransferase activity; IDA:MGI.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   LPD6B_HUMAN             Reviewed;         183 AA.
AC   Q8NI32; D3DP90; Q53TK0; Q7Z747; Q8IXK7;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 6B;
DE   Flags: Precursor;
GN   Name=LYPD6B;
//
ID   LPHN1_HUMAN             Reviewed;        1474 AA.
AC   O94910; Q96IE7; Q9BU07; Q9HAR3;
DE   RecName: Full=Latrophilin-1;
DE   AltName: Full=Calcium-independent alpha-latrotoxin receptor 1;
DE            Short=CIRL-1;
DE   AltName: Full=Lectomedin-2;
DE   Flags: Precursor;
GN   Name=LPHN1; Synonyms=KIAA0821, LEC2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0016524; F:latrotoxin receptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
//
ID   LPHN2_HUMAN             Reviewed;        1459 AA.
AC   O95490; A5XEI2; B1ALT8; B1ALT9; B1ALU0; B1ALU2; B1ALU4; B1ALU5;
AC   B1ALU6; O94882; Q5VX76; Q9UKY5; Q9UKY6;
DE   RecName: Full=Latrophilin-2;
DE   AltName: Full=Calcium-independent alpha-latrotoxin receptor 2;
DE            Short=CIRL-2;
DE   AltName: Full=Latrophilin homolog 1;
DE   AltName: Full=Lectomedin-1;
DE   Flags: Precursor;
GN   Name=LPHN2; Synonyms=KIAA0786, LEC1, LPHH1;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0016524; F:latrotoxin receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   LPHN3_HUMAN             Reviewed;        1447 AA.
AC   Q9HAR2; O94867; Q9NWK5;
DE   RecName: Full=Latrophilin-3;
DE   AltName: Full=Calcium-independent alpha-latrotoxin receptor 3;
DE            Short=CIRL-3;
DE   AltName: Full=Lectomedin-3;
DE   Flags: Precursor;
GN   Name=LPHN3; Synonyms=KIAA0768, LEC3;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   LPH_HUMAN               Reviewed;        1927 AA.
AC   P09848; Q4ZG58;
DE   RecName: Full=Lactase-phlorizin hydrolase;
DE   AltName: Full=Lactase-glycosylceramidase;
DE   Includes:
DE     RecName: Full=Lactase;
DE              EC=3.2.1.108;
DE   Includes:
DE     RecName: Full=Phlorizin hydrolase;
DE              EC=3.2.1.62;
DE   Flags: Precursor;
GN   Name=LCT; Synonyms=LPH;
DR   GO; GO:0017042; F:glycosylceramidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000016; F:lactase activity; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044245; P:polysaccharide digestion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LPIN1_HUMAN             Reviewed;         890 AA.
AC   Q14693; B4DET9; B4DGS4; B4DGZ6; B5MC18; B7Z858; D6W506; E7ESE7;
AC   Q53T25;
DE   RecName: Full=Phosphatidate phosphatase LPIN1;
DE            EC=3.1.3.4;
DE   AltName: Full=Lipin-1;
GN   Name=LPIN1; Synonyms=KIAA0188;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0009062; P:fatty acid catabolic process; ISS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0006642; P:triglyceride mobilization; ISS:UniProtKB.
//
ID   LPIN2_HUMAN             Reviewed;         896 AA.
AC   Q92539; A7MD25; D3DUH3;
DE   RecName: Full=Phosphatidate phosphatase LPIN2;
DE            EC=3.1.3.4;
DE   AltName: Full=Lipin-2;
GN   Name=LPIN2; Synonyms=KIAA0249;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; ISS:GOC.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; ISS:UniProtKB.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   LPIN3_HUMAN             Reviewed;         851 AA.
AC   Q9BQK8; B2RTT5; Q5TDB9; Q9NPY8; Q9UJE5;
DE   RecName: Full=Phosphatidate phosphatase LPIN3;
DE            EC=3.1.3.4;
DE   AltName: Full=Lipin-3;
DE   AltName: Full=Lipin-3-like;
GN   Name=LPIN3; Synonyms=LIPN3L;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LPP1_HUMAN              Reviewed;         284 AA.
AC   O14494; B7ZKN8; G3XA95; O60457; O60463; Q17RZ4;
DE   RecName: Full=Lipid phosphate phosphohydrolase 1;
DE            EC=3.1.3.4;
DE   AltName: Full=PAP2-alpha;
DE   AltName: Full=Phosphatidate phosphohydrolase type 2a;
DE   AltName: Full=Phosphatidic acid phosphatase 2a;
DE            Short=PAP-2a;
DE            Short=PAP2a;
GN   Name=PPAP2A; Synonyms=LPP1;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0008354; P:germ cell migration; TAS:ProtInc.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0046839; P:phospholipid dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   LPP2_HUMAN              Reviewed;         288 AA.
AC   O43688; A6NLV0; E9PAY8;
DE   RecName: Full=Lipid phosphate phosphohydrolase 2;
DE            EC=3.1.3.4;
DE   AltName: Full=PAP2-gamma;
DE            Short=PAP2-G;
DE   AltName: Full=Phosphatidate phosphohydrolase type 2c;
DE   AltName: Full=Phosphatidic acid phosphatase 2c;
DE            Short=PAP-2c;
DE            Short=PAP2c;
GN   Name=PPAP2C; Synonyms=LPP2;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:ProtInc.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   LPP3_HUMAN              Reviewed;         311 AA.
AC   O14495; B2R651; D3DQ52; Q5U0F7; Q96GW0; Q99782;
DE   RecName: Full=Lipid phosphate phosphohydrolase 3;
DE            EC=3.1.3.4;
DE   AltName: Full=PAP2-beta;
DE   AltName: Full=Phosphatidate phosphohydrolase type 2b;
DE   AltName: Full=Phosphatidic acid phosphatase 2b;
DE            Short=PAP-2b;
DE            Short=PAP2b;
DE   AltName: Full=Vascular endothelial growth factor and type I collagen-inducible protein;
DE            Short=VCIP;
GN   Name=PPAP2B; Synonyms=LPP3;
DR   GO; GO:0042577; F:lipid phosphatase activity; IEA:Ensembl.
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0044329; P:canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0044328; P:canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0044330; P:canonical Wnt signaling pathway involved in positive regulation of wound healing; IMP:BHF-UCL.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0008354; P:germ cell migration; TAS:ProtInc.
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   LPP60_HUMAN             Reviewed;         573 AA.
AC   Q86U10; B9EGQ2; Q8IV80;
DE   RecName: Full=60 kDa lysophospholipase;
DE            EC=3.1.1.5;
DE   Includes:
DE     RecName: Full=L-asparaginase;
DE              EC=3.5.1.1;
DE     AltName: Full=L-asparagine amidohydrolase;
DE   Includes:
DE     RecName: Full=Platelet-activating factor acetylhydrolase;
DE              Short=PAF acetylhydrolase;
DE              EC=3.1.1.47;
GN   Name=ASPG; Synonyms=C14orf76;
DR   GO; GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004067; F:asparaginase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006528; P:asparagine metabolic process; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
//
ID   LPPR1_HUMAN             Reviewed;         325 AA.
AC   Q8TBJ4; Q5VX23; Q9NXE2;
DE   RecName: Full=Lipid phosphate phosphatase-related protein type 1;
DE   AltName: Full=Plasticity-related gene 3 protein;
DE            Short=PRG-3;
GN   Name=LPPR1; Synonyms=PRG3;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; IEA:InterPro.
//
ID   LPPR2_HUMAN             Reviewed;         343 AA.
AC   Q96GM1; Q5CZ76; Q8N1U4; Q9H929;
DE   RecName: Full=Lipid phosphate phosphatase-related protein type 2;
DE            EC=3.1.3.4;
DE   AltName: Full=Plasticity-related gene 4 protein;
DE            Short=PRG-4;
GN   Name=LPPR2; Synonyms=PRG4;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
//
ID   LPPR3_HUMAN             Reviewed;         718 AA.
AC   Q6T4P5; Q86XQ4; Q96EH1; Q9BQF9; Q9HAJ4;
DE   RecName: Full=Lipid phosphate phosphatase-related protein type 3;
DE            EC=3.1.3.4;
DE   AltName: Full=PAP-2-like protein 2;
DE   AltName: Full=Plasticity-related gene 2 protein;
DE            Short=PRG-2;
GN   Name=LPPR3; Synonyms=PHP2, PRG2;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
//
ID   LPPR4_HUMAN             Reviewed;         763 AA.
AC   Q7Z2D5; E7EPS1; O75043; Q5T9R9; Q86XQ5; Q8N3F1; Q96MP0;
DE   RecName: Full=Lipid phosphate phosphatase-related protein type 4;
DE            EC=3.1.3.4;
DE   AltName: Full=Brain-specific phosphatidic acid phosphatase-like protein 1;
DE   AltName: Full=Plasticity-related gene 1 protein;
DE            Short=PRG-1;
GN   Name=LPPR4; Synonyms=KIAA0455, PRG1;
DR   GO; GO:0042577; F:lipid phosphatase activity; IEA:InterPro.
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007409; P:axonogenesis; IEA:InterPro.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0046839; P:phospholipid dephosphorylation; IEA:InterPro.
//
ID   LPPRC_HUMAN             Reviewed;        1394 AA.
AC   P42704; A0PJE3; A8K1V1; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84;
DE   RecName: Full=Leucine-rich PPR motif-containing protein, mitochondrial;
DE   AltName: Full=130 kDa leucine-rich protein;
DE            Short=LRP 130;
DE   AltName: Full=GP130;
DE   Flags: Precursor;
GN   Name=LRPPRC; Synonyms=LRP130;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:HGNC.
DR   GO; GO:0008017; F:microtubule binding; TAS:HGNC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; TAS:HGNC.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0000961; P:negative regulation of mitochondrial RNA catabolic process; IEA:Ensembl.
DR   GO; GO:0070129; P:regulation of mitochondrial translation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LPPR5_HUMAN             Reviewed;         321 AA.
AC   Q32ZL2; A8MPX4; B7UCH3; Q32ZD0; Q3ZCU7;
DE   RecName: Full=Lipid phosphate phosphatase-related protein type 5;
DE            EC=3.1.3.-;
DE   AltName: Full=Phosphatidic acid phosphatase 2d;
DE   AltName: Full=Plasticity-related gene 5 protein;
DE            Short=PRG-5;
GN   Name=LPPR5; Synonyms=PAP2D;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   LPP_HUMAN               Reviewed;         612 AA.
AC   Q93052; A1L4L6; D3DNV6; Q8NFX5;
DE   RecName: Full=Lipoma-preferred partner;
DE   AltName: Full=LIM domain-containing preferred translocation partner in lipoma;
GN   Name=LPP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   LPXN_HUMAN              Reviewed;         386 AA.
AC   O60711; B2R8B4; B4DV71; Q53FW6; Q6FI07;
DE   RecName: Full=Leupaxin;
GN   Name=LPXN; Synonyms=LDLP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LQK1_HUMAN              Reviewed;          88 AA.
AC   Q8TAF5;
DE   RecName: Full=Putative uncharacterized protein LQK1;
DE   AltName: Full=FLVCR1 antisense RNA 1;
GN   Name=FLVCR1-AS1; Synonyms=LQK1;
//
ID   LR10B_HUMAN             Reviewed;         292 AA.
AC   A6NIK2;
DE   RecName: Full=Leucine-rich repeat-containing protein 10B;
GN   Name=LRRC10B;
//
ID   LR14B_HUMAN             Reviewed;         514 AA.
AC   A6NHZ5;
DE   RecName: Full=Leucine-rich repeat-containing protein 14B;
GN   Name=LRRC14B;
//
ID   LR16A_HUMAN             Reviewed;        1371 AA.
AC   Q5VZK9; B8X1J0; Q6ZUH5; Q6ZW07; Q9NXU7;
DE   RecName: Full=Leucine-rich repeat-containing protein 16A;
DE   AltName: Full=CARMIL homolog;
GN   Name=LRRC16A; Synonyms=CARMIL, CARMIL1a, LRRC16;
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0007015; P:actin filament organization; NAS:BHF-UCL.
DR   GO; GO:0051638; P:barbed-end actin filament uncapping; ISS:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IMP:BHF-UCL.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:BHF-UCL.
DR   GO; GO:2000813; P:negative regulation of barbed-end actin filament capping; ISS:UniProt.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProt.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProt.
DR   GO; GO:1902745; P:positive regulation of lamellipodium organization; IDA:UniProt.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProt.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IMP:UniProt.
DR   GO; GO:0031529; P:ruffle organization; IMP:BHF-UCL.
DR   GO; GO:0046415; P:urate metabolic process; IMP:BHF-UCL.
//
ID   LR16B_HUMAN             Reviewed;        1372 AA.
AC   Q8ND23; Q8TEF7; Q96HS9;
DE   RecName: Full=Leucine-rich repeat-containing protein 16B;
GN   Name=LRRC16B; Synonyms=C14orf121;
//
ID   LR16C_HUMAN             Reviewed;        1435 AA.
AC   Q6F5E8; B8X2Z3;
DE   RecName: Full=Leucine-rich repeat-containing protein 16C;
DE   AltName: Full=RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein;
GN   Name=RLTPR; Synonyms=CARMIL2b, LRRC16C;
//
ID   LR2BP_HUMAN             Reviewed;         347 AA.
AC   Q9P2M1; A6NJR7; A7E219; B3KX83; Q9NSN6;
DE   RecName: Full=LRP2-binding protein;
DE   AltName: Full=Megalin-binding protein;
DE            Short=MegBP;
GN   Name=LRP2BP; Synonyms=KIAA1325;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
//
ID   LR37B_HUMAN             Reviewed;         947 AA.
AC   Q96QE4; Q17RC9; Q5YKG6;
DE   RecName: Full=Leucine-rich repeat-containing protein 37B;
DE   AltName: Full=C66 SLIT-like testicular protein;
DE   Flags: Precursor;
GN   Name=LRRC37B;
//
ID   LR75A_HUMAN             Reviewed;         344 AA.
AC   Q8NAA5;
DE   RecName: Full=Leucine-rich repeat-containing protein 75A;
DE   AltName: Full=Leucine-rich repeat-containing protein FAM211A;
GN   Name=LRRC75A; Synonyms=C17orf76, FAM211A;
//
ID   LR75B_HUMAN             Reviewed;         315 AA.
AC   Q2VPJ9; Q8N0S9; Q8N8B1;
DE   RecName: Full=Leucine-rich repeat-containing protein 75B;
DE   AltName: Full=Leucine-rich repeat-containing protein FAM211B;
GN   Name=LRRC75B; Synonyms=C22orf36, FAM211B;
//
ID   LRAD1_HUMAN             Reviewed;         205 AA.
AC   Q5T700; A0PJY0; B7ZME3; Q5T6Z9;
DE   RecName: Full=Low-density lipoprotein receptor class A domain-containing protein 1;
GN   Name=LDLRAD1;
//
ID   LRAD2_HUMAN             Reviewed;         272 AA.
AC   Q5SZI1; B9EJB3; Q6ZSN5;
DE   RecName: Full=Low-density lipoprotein receptor class A domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=LDLRAD2;
//
ID   LRAD3_HUMAN             Reviewed;         345 AA.
AC   Q86YD5; B9EG81; Q8NBJ0;
DE   RecName: Full=Low-density lipoprotein receptor class A domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=LDLRAD3;
DR   GO; GO:0001540; F:beta-amyloid binding; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0070613; P:regulation of protein processing; IEA:Ensembl.
//
ID   LRAD4_HUMAN             Reviewed;         306 AA.
AC   O15165; B3KNT9; E9PAY9; K7EN38; O15166; O15167; O15168; Q5U646;
AC   Q6NXP3;
DE   RecName: Full=Low-density lipoprotein receptor class A domain-containing protein 4;
GN   Name=LDLRAD4; Synonyms=C18orf1;
//
ID   LRAT_HUMAN              Reviewed;         230 AA.
AC   O95237; A8K983; Q8N716;
DE   RecName: Full=Lecithin retinol acyltransferase;
DE            EC=2.3.1.135;
DE   AltName: Full=Phosphatidylcholine--retinol O-acyltransferase;
GN   Name=LRAT;
DR   GO; GO:0047173; F:phosphatidylcholine-retinol O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0001972; F:retinoic acid binding; IEA:Ensembl.
DR   GO; GO:0019841; F:retinol binding; IEA:Ensembl.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; TAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   GO; GO:0006776; P:vitamin A metabolic process; IEA:Ensembl.
//
ID   LRBA_HUMAN              Reviewed;        2863 AA.
AC   P50851; Q4W5J4; Q4W5L6; Q8NFQ0; Q9H2U3; Q9H2U4;
DE   RecName: Full=Lipopolysaccharide-responsive and beige-like anchor protein;
DE   AltName: Full=Beige-like protein;
DE   AltName: Full=CDC4-like protein;
GN   Name=LRBA; Synonyms=BGL, CDC4L, LBA;
//
ID   LRC10_HUMAN             Reviewed;         277 AA.
AC   Q5BKY1; Q6ZVY4;
DE   RecName: Full=Leucine-rich repeat-containing protein 10;
GN   Name=LRRC10;
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
//
ID   LRC14_HUMAN             Reviewed;         493 AA.
AC   Q15048; A8K0A8; D3DWM8;
DE   RecName: Full=Leucine-rich repeat-containing protein 14;
GN   Name=LRRC14; Synonyms=KIAA0014;
//
ID   LRC15_HUMAN             Reviewed;         581 AA.
AC   Q8TF66; Q495Q6; Q7RTN7;
DE   RecName: Full=Leucine-rich repeat-containing protein 15;
DE   AltName: Full=Leucine-rich repeat protein induced by beta-amyloid homolog;
DE            Short=hLib;
DE   Flags: Precursor;
GN   Name=LRRC15; Synonyms=LIB;
DR   GO; GO:0005518; F:collagen binding; IDA:UniProt.
DR   GO; GO:0001968; F:fibronectin binding; IDA:UniProt.
DR   GO; GO:0043236; F:laminin binding; IDA:UniProt.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IMP:UniProt.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProt.
DR   GO; GO:0046813; P:receptor-mediated virion attachment to host cell; IMP:UniProt.
//
ID   LRC17_HUMAN             Reviewed;         441 AA.
AC   Q8N6Y2; Q13288; Q6UWA7; Q75MG5;
DE   RecName: Full=Leucine-rich repeat-containing protein 17;
DE   AltName: Full=p37NB;
DE   Flags: Precursor;
GN   Name=LRRC17; Synonyms=P37NB; ORFNames=UNQ3076/PRO9909;
DR   GO; GO:0048539; P:bone marrow development; ISS:UniProtKB.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
//
ID   LRC18_HUMAN             Reviewed;         261 AA.
AC   Q8N456; Q6UY02;
DE   RecName: Full=Leucine-rich repeat-containing protein 18;
GN   Name=LRRC18; ORFNames=UNQ9338/PRO34010;
//
ID   LRC19_HUMAN             Reviewed;         370 AA.
AC   Q9H756; A0AV00; B9EG91;
DE   RecName: Full=Leucine-rich repeat-containing protein 19;
DE   Flags: Precursor;
GN   Name=LRRC19;
//
ID   LRC20_HUMAN             Reviewed;         184 AA.
AC   Q8TCA0; Q5T6D4; Q5T6D6; Q9NVA6; Q9NVG3;
DE   RecName: Full=Leucine-rich repeat-containing protein 20;
GN   Name=LRRC20; ORFNames=UNQ2429/PRO4989;
//
ID   LRC23_HUMAN             Reviewed;         343 AA.
AC   Q53EV4; A8K8C6; D3DUT1; Q8N6K6; Q92977; Q99620;
DE   RecName: Full=Leucine-rich repeat-containing protein 23;
DE   AltName: Full=Leucine-rich protein B7;
GN   Name=LRRC23; Synonyms=LRPB7;
//
ID   LRC24_HUMAN             Reviewed;         513 AA.
AC   Q50LG9;
DE   RecName: Full=Leucine-rich repeat-containing protein 24;
DE   Flags: Precursor;
GN   Name=LRRC24;
//
ID   LRC26_HUMAN             Reviewed;         334 AA.
AC   Q2I0M4; B9EIR7; C3RUL3; Q5VSG2;
DE   RecName: Full=Leucine-rich repeat-containing protein 26;
DE   AltName: Full=BK channel auxiliary gamma subunit LRRC26;
DE   AltName: Full=Cytokeratin-associated protein in cancer;
DE   Flags: Precursor;
GN   Name=LRRC26; Synonyms=CAPC;
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   LRC25_HUMAN             Reviewed;         305 AA.
AC   Q8N386; Q6IQ00; Q8N9A5;
DE   RecName: Full=Leucine-rich repeat-containing protein 25;
DE   AltName: Full=Monocyte and plasmacytoid-activated protein;
DE   Flags: Precursor;
GN   Name=LRRC25; Synonyms=MAPA; ORFNames=UNQ6169/PRO20174;
//
ID   LRC27_HUMAN             Reviewed;         530 AA.
AC   Q9C0I9; A6NE72; A6NJB4; A6NKD3; D3DRH0; Q5SZH6; Q5SZH8; Q5SZH9;
AC   Q86XT5; Q8N7C8; Q8NA21;
DE   RecName: Full=Leucine-rich repeat-containing protein 27;
GN   Name=LRRC27; Synonyms=KIAA1674;
//
ID   LRC28_HUMAN             Reviewed;         367 AA.
AC   Q86X40; A8KA22; Q6UY49; Q6ZSS6;
DE   RecName: Full=Leucine-rich repeat-containing protein 28;
GN   Name=LRRC28; ORFNames=UNQ436/PRO867;
//
ID   LRC30_HUMAN             Reviewed;         301 AA.
AC   A6NM36;
DE   RecName: Full=Leucine-rich repeat-containing protein 30;
GN   Name=LRRC30;
//
ID   LRC31_HUMAN             Reviewed;         552 AA.
AC   Q6UY01; B7ZL44; Q17RA3; Q8N848; Q9H5N5;
DE   RecName: Full=Leucine-rich repeat-containing protein 31;
GN   Name=LRRC31; ORFNames=UNQ9367/PRO34156;
//
ID   LRC29_HUMAN             Reviewed;         223 AA.
AC   Q8WV35; B2RE92; Q9UKA0;
DE   RecName: Full=Leucine-rich repeat-containing protein 29;
DE   AltName: Full=F-box and leucine-rich repeat protein 9;
DE   AltName: Full=F-box protein FBL9;
DE   AltName: Full=F-box/LRR-repeat protein 9;
GN   Name=LRRC29; Synonyms=FBL9, FBXL9;
//
ID   LRC32_HUMAN             Reviewed;         662 AA.
AC   Q14392; Q86V06;
DE   RecName: Full=Leucine-rich repeat-containing protein 32;
DE   AltName: Full=Garpin;
DE   AltName: Full=Glycoprotein A repetitions predominant;
DE            Short=GARP;
DE   Flags: Precursor;
GN   Name=LRRC32; Synonyms=D11S833E, GARP;
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
//
ID   LRC34_HUMAN             Reviewed;         419 AA.
AC   Q8IZ02; B4DEJ7; E9PBH2; G5E9T7;
DE   RecName: Full=Leucine-rich repeat-containing protein 34;
GN   Name=LRRC34;
//
ID   LRC36_HUMAN             Reviewed;         754 AA.
AC   Q1X8D7; A4FTV6; A6NDE9; A8K8E6; Q7Z5K5;
DE   RecName: Full=Leucine-rich repeat-containing protein 36;
DE   AltName: Full=ROR gamma-binding protein 70;
GN   Name=LRRC36; Synonyms=RORBP70;
//
ID   LRC38_HUMAN             Reviewed;         294 AA.
AC   Q5VT99; Q96B32;
DE   RecName: Full=Leucine-rich repeat-containing protein 38;
DE   AltName: Full=BK channel auxiliary gamma subunit LRRC38;
DE   Flags: Precursor;
GN   Name=LRRC38;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   LRC39_HUMAN             Reviewed;         335 AA.
AC   Q96DD0; B3KUD2; D3DT56; Q5VVK7;
DE   RecName: Full=Leucine-rich repeat-containing protein 39;
DE   AltName: Full=Densin hlg;
GN   Name=LRRC39; ORFNames=UNQ6500/PRO21368;
//
ID   LRC3B_HUMAN             Reviewed;         259 AA.
AC   Q96PB8; Q5M8T0;
DE   RecName: Full=Leucine-rich repeat-containing protein 3B;
DE   AltName: Full=Leucine-rich repeat protein LRP15;
DE   Flags: Precursor;
GN   Name=LRRC3B; Synonyms=LRP15; ORFNames=UNQ195/PRO221;
//
ID   LRC40_HUMAN             Reviewed;         602 AA.
AC   Q9H9A6; Q9BTR7; Q9NSK1; Q9NXC1;
DE   RecName: Full=Leucine-rich repeat-containing protein 40;
GN   Name=LRRC40;
//
ID   LRC41_HUMAN             Reviewed;         812 AA.
AC   Q15345; A8K5G8; Q3MJ96; Q5TDF5; Q71RA8; Q9BSM0;
DE   RecName: Full=Leucine-rich repeat-containing protein 41;
DE   AltName: Full=Protein Muf1;
GN   Name=LRRC41; Synonyms=MUF1; ORFNames=PP7759;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   LRC42_HUMAN             Reviewed;         428 AA.
AC   Q9Y546; D3DQ46; Q8N2Q8;
DE   RecName: Full=Leucine-rich repeat-containing protein 42;
GN   Name=LRRC42;
//
ID   LRC43_HUMAN             Reviewed;         656 AA.
AC   Q8N309; Q6ZVT9;
DE   RecName: Full=Leucine-rich repeat-containing protein 43;
GN   Name=LRRC43;
//
ID   LRC45_HUMAN             Reviewed;         670 AA.
AC   Q96CN5;
DE   RecName: Full=Leucine-rich repeat-containing protein 45;
GN   Name=LRRC45;
//
ID   LRC46_HUMAN             Reviewed;         321 AA.
AC   Q96FV0; A8K9Q0;
DE   RecName: Full=Leucine-rich repeat-containing protein 46;
GN   Name=LRRC46;
//
ID   LRC47_HUMAN             Reviewed;         583 AA.
AC   Q8N1G4; Q9ULN5;
DE   RecName: Full=Leucine-rich repeat-containing protein 47;
GN   Name=LRRC47; Synonyms=KIAA1185;
DR   GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LRC48_HUMAN             Reviewed;         523 AA.
AC   Q9H069; A8KAE6; Q86SF9; Q86W73; Q8IWG0;
DE   RecName: Full=Leucine-rich repeat-containing protein 48;
GN   Name=LRRC48;
//
ID   LRC49_HUMAN             Reviewed;         686 AA.
AC   Q8IUZ0; B7Z366; G5E9T5; H0YLN4; Q9NXM6;
DE   RecName: Full=Leucine-rich repeat-containing protein 49;
DE   AltName: Full=Tubulin polyglutamylase complex subunit 4;
DE            Short=PGs4;
GN   Name=LRRC49;
//
ID   LRC4B_HUMAN             Reviewed;         713 AA.
AC   Q9NT99; Q3ZCQ4; Q58F20;
DE   RecName: Full=Leucine-rich repeat-containing protein 4B;
DE   AltName: Full=Netrin-G3 ligand;
DE            Short=NGL-3;
DE   Flags: Precursor;
GN   Name=LRRC4B; Synonyms=LRIG4;
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.
//
ID   LRC4C_HUMAN             Reviewed;         640 AA.
AC   Q9HCJ2; A8K0T1; Q7L0N3;
DE   RecName: Full=Leucine-rich repeat-containing protein 4C;
DE   AltName: Full=Netrin-G1 ligand;
DE            Short=NGL-1;
DE   Flags: Precursor;
GN   Name=LRRC4C; Synonyms=KIAA1580, NGL1; ORFNames=UNQ292/PRO331;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.
//
ID   LRC51_HUMAN             Reviewed;         192 AA.
AC   Q96E66; B2R7X1; B6CZ35; B6CZ36; B6CZ37; B6CZ38; B6CZ39; B7Z5I4;
DE   RecName: Full=Leucine-rich repeat-containing protein 51;
DE   AltName: Full=Protein LRTOMT1;
GN   Name=LRTOMT; Synonyms=LRRC51;
//
ID   LRC52_HUMAN             Reviewed;         313 AA.
AC   Q8N7C0; A2RUN7; Q5T9K5;
DE   RecName: Full=Leucine-rich repeat-containing protein 52;
DE   AltName: Full=BK channel auxiliary gamma subunit LRRC52;
DE   Flags: Precursor;
GN   Name=LRRC52;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   LRC53_HUMAN             Reviewed;        1247 AA.
AC   A6NM62;
DE   RecName: Full=Leucine-rich repeat-containing protein 53;
GN   Name=LRRC53;
//
ID   LRC55_HUMAN             Reviewed;         311 AA.
AC   Q6ZSA7; A7E2U7; B2RN81;
DE   RecName: Full=Leucine-rich repeat-containing protein 55;
DE   AltName: Full=BK channel auxiliary gamma subunit LRRC55;
DE   Flags: Precursor;
GN   Name=LRRC55;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   LRC56_HUMAN             Reviewed;         542 AA.
AC   Q8IYG6; Q8N3Q4;
DE   RecName: Full=Leucine-rich repeat-containing protein 56;
GN   Name=LRRC56;
//
ID   LRC57_HUMAN             Reviewed;         239 AA.
AC   Q8N9N7; Q7Z2Z6; Q8N1T6;
DE   RecName: Full=Leucine-rich repeat-containing protein 57;
GN   Name=LRRC57;
//
ID   LRC58_HUMAN             Reviewed;         371 AA.
AC   Q96CX6;
DE   RecName: Full=Leucine-rich repeat-containing protein 58;
GN   Name=LRRC58;
//
ID   LRC59_HUMAN             Reviewed;         307 AA.
AC   Q96AG4; B2RE83; D3DTX8; Q9P189;
DE   RecName: Full=Leucine-rich repeat-containing protein 59;
DE   AltName: Full=Ribosome-binding protein p34;
DE            Short=p34;
GN   Name=LRRC59; ORFNames=PRO1855;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   LRC61_HUMAN             Reviewed;         259 AA.
AC   Q9BV99; B3KUW0; D3DWY8;
DE   RecName: Full=Leucine-rich repeat-containing protein 61;
GN   Name=LRRC61;
//
ID   LRC66_HUMAN             Reviewed;         880 AA.
AC   Q68CR7;
DE   RecName: Full=Leucine-rich repeat-containing protein 66;
GN   Name=LRRC66;
//
ID   LRC69_HUMAN             Reviewed;         347 AA.
AC   Q6ZNQ3;
DE   RecName: Full=Leucine-rich repeat-containing protein 69;
GN   Name=LRRC69;
//
ID   LRC71_HUMAN             Reviewed;         559 AA.
AC   Q8N4P6; Q96M24;
DE   RecName: Full=Leucine-rich repeat-containing protein 71;
GN   Name=LRRC71; Synonyms=C1orf92;
//
ID   LRC63_HUMAN             Reviewed;         580 AA.
AC   Q05C16; Q5TBN0;
DE   RecName: Full=Leucine-rich repeat-containing protein 63;
GN   Name=LRRC63;
//
ID   LRC72_HUMAN             Reviewed;         287 AA.
AC   A6NJI9;
DE   RecName: Full=Leucine-rich repeat-containing protein 72;
GN   Name=LRRC72;
//
ID   LRC73_HUMAN             Reviewed;         316 AA.
AC   Q5JTD7;
DE   RecName: Full=Leucine-rich repeat-containing protein 73;
GN   Name=LRRC73; Synonyms=C6orf154;
//
ID   LRC74_HUMAN             Reviewed;         488 AA.
AC   Q0VAA2; Q6ZUG6; Q9Y627;
DE   RecName: Full=Leucine-rich repeat-containing protein 74;
GN   Name=LRRC74; Synonyms=C14orf166B;
//
ID   LRC8A_HUMAN             Reviewed;         810 AA.
AC   Q8IWT6; Q6UXM2; Q8NCI0; Q9P2B1;
DE   RecName: Full=Leucine-rich repeat-containing protein 8A;
GN   Name=LRRC8A; Synonyms=KIAA1437, LRRC8; ORFNames=UNQ221/PRO247;
DR   GO; GO:0002329; P:pre-B cell differentiation; ISS:UniProtKB.
//
ID   LRC8B_HUMAN             Reviewed;         803 AA.
AC   Q6P9F7; D3DT28; Q6UY21; Q8N106; Q92627;
DE   RecName: Full=Leucine-rich repeat-containing protein 8B;
DE   AltName: Full=T-cell activation leucine repeat-rich protein;
DE            Short=TA-LRRP;
GN   Name=LRRC8B; Synonyms=KIAA0231; ORFNames=UNQ6413/PRO21207;
//
ID   LRC8C_HUMAN             Reviewed;         803 AA.
AC   Q8TDW0; B3KXS9; Q29RV6; Q9H075;
DE   RecName: Full=Leucine-rich repeat-containing protein 8C;
DE   AltName: Full=Factor for adipocyte differentiation 158;
GN   Name=LRRC8C; Synonyms=AD158, FAD158;
//
ID   LRC8D_HUMAN             Reviewed;         858 AA.
AC   Q7L1W4; D3DT29; Q6UWB2; Q9NVW3;
DE   RecName: Full=Leucine-rich repeat-containing protein 8D;
DE   AltName: Full=Leucine-rich repeat-containing protein 5;
GN   Name=LRRC8D; Synonyms=LRRC5; ORFNames=UNQ213/PRO239;
//
ID   LRC8E_HUMAN             Reviewed;         796 AA.
AC   Q6NSJ5; B3KR78; Q2YDY3; Q7L236; Q8N3B0; Q9H5H8;
DE   RecName: Full=Leucine-rich repeat-containing protein 8E;
GN   Name=LRRC8E;
//
ID   LRCC1_HUMAN             Reviewed;        1032 AA.
AC   Q9C099; B4DYX6; B5RI11; Q8N768; Q96DK7; Q96N01;
DE   RecName: Full=Leucine-rich repeat and coiled-coil domain-containing protein 1;
DE   AltName: Full=Centrosomal leucine-rich repeat and coiled-coil domain-containing protein;
GN   Name=LRRCC1; Synonyms=CLERC, KIAA1764;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   LRCH1_HUMAN             Reviewed;         728 AA.
AC   Q9Y2L9; B7ZLL5; F8W6F0; Q17R43; Q2KHR1; Q5TBU9; Q7Z5F6; Q7Z5F7;
DE   RecName: Full=Leucine-rich repeat and calponin homology domain-containing protein 1;
DE   AltName: Full=Calponin homology domain-containing protein 1;
DE   AltName: Full=Neuronal protein 81;
DE            Short=NP81;
GN   Name=LRCH1; Synonyms=CHDC1, KIAA1016;
//
ID   LRCH2_HUMAN             Reviewed;         765 AA.
AC   Q5VUJ6; F5H2T1; Q08AD5; Q9HA88; Q9P233;
DE   RecName: Full=Leucine-rich repeat and calponin homology domain-containing protein 2;
GN   Name=LRCH2; Synonyms=KIAA1495;
//
ID   LRCH3_HUMAN             Reviewed;         777 AA.
AC   Q96II8; Q96FP9; Q9NT52;
DE   RecName: Full=Leucine-rich repeat and calponin homology domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=LRCH3;
//
ID   LRCH4_HUMAN             Reviewed;         683 AA.
AC   O75427; A4D2D5; Q8WV85; Q96ID0;
DE   RecName: Full=Leucine-rich repeat and calponin homology domain-containing protein 4;
DE   AltName: Full=Leucine-rich repeat neuronal protein 4;
DE            Short=Leucine-rich neuronal protein;
GN   Name=LRCH4; Synonyms=LRN, LRRN1, LRRN4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   LRCL1_HUMAN             Reviewed;         159 AA.
AC   A6NCL2; H9BFB1;
DE   RecName: Full=Leucine-rich colipase-like protein 1;
DE   Flags: Precursor;
GN   Name=LRCOL1;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
//
ID   LRFN1_HUMAN             Reviewed;         771 AA.
AC   Q9P244; Q8TBS9;
DE   RecName: Full=Leucine-rich repeat and fibronectin type III domain-containing protein 1;
DE   AltName: Full=Synaptic adhesion-like molecule 2;
DE   Flags: Precursor;
GN   Name=LRFN1; Synonyms=KIAA1484, SALM2;
//
ID   LRFN2_HUMAN             Reviewed;         789 AA.
AC   Q9ULH4; A5PKU3; Q5SYP9;
DE   RecName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 2;
DE   AltName: Full=Synaptic adhesion-like molecule 1;
DE   Flags: Precursor;
GN   Name=LRFN2; Synonyms=KIAA1246, SALM1;
//
ID   LRFN3_HUMAN             Reviewed;         628 AA.
AC   Q9BTN0; Q6UY10;
DE   RecName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 3;
DE   AltName: Full=Synaptic adhesion-like molecule 4;
DE   Flags: Precursor;
GN   Name=LRFN3; Synonyms=SALM4; ORFNames=UNQ5865/PRO34192;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   LRFN4_HUMAN             Reviewed;         635 AA.
AC   Q6PJG9; Q4VBZ3; Q59GV4; Q8N644; Q9BWJ0;
DE   RecName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=LRFN4; Synonyms=SALM3;
//
ID   LRFN5_HUMAN             Reviewed;         719 AA.
AC   Q96NI6; B3KU78; Q86XL2;
DE   RecName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 5;
DE   Flags: Precursor;
GN   Name=LRFN5; Synonyms=C14orf146, SALM5;
//
ID   LRGUK_HUMAN             Reviewed;         825 AA.
AC   Q96M69; Q2M3I1;
DE   RecName: Full=Leucine-rich repeat and guanylate kinase domain-containing protein;
GN   Name=LRGUK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
//
ID   LRIF1_HUMAN             Reviewed;         769 AA.
AC   Q5T3J3; Q86XS4; Q8N3B6; Q96HT4; Q9NUM5; Q9NV32;
DE   RecName: Full=Ligand-dependent nuclear receptor-interacting factor 1;
DE   AltName: Full=Receptor-interacting factor 1;
GN   Name=LRIF1; Synonyms=C1orf103, RIF1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LRIG1_HUMAN             Reviewed;        1093 AA.
AC   Q96JA1; Q6IQ51; Q96CF9; Q9BYB8; Q9UFI4;
DE   RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 1;
DE            Short=LIG-1;
DE   Flags: Precursor;
GN   Name=LRIG1; Synonyms=LIG1;
//
ID   LRIG2_HUMAN             Reviewed;        1065 AA.
AC   O94898; Q9NSN2;
DE   RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 2;
DE            Short=LIG-2;
DE   Flags: Precursor;
GN   Name=LRIG2; Synonyms=KIAA0806, LIG2;
//
ID   LRIG3_HUMAN             Reviewed;        1119 AA.
AC   Q6UXM1; Q6UXL7; Q8NC72;
DE   RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 3;
DE            Short=LIG-3;
DE   Flags: Precursor;
GN   Name=LRIG3; Synonyms=LIG3; ORFNames=UNQ287/PRO326/PRO335;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   LRIQ1_HUMAN             Reviewed;        1722 AA.
AC   Q96JM4; Q567P4; Q9BS17; Q9HA36;
DE   RecName: Full=Leucine-rich repeat and IQ domain-containing protein 1;
GN   Name=LRRIQ1; Synonyms=KIAA1801;
//
ID   LRIQ3_HUMAN             Reviewed;         624 AA.
AC   A6PVS8; A6PVS9; Q6P5P7; Q6ZMV4; Q8WUE0;
DE   RecName: Full=Leucine-rich repeat and IQ domain-containing protein 3;
DE   AltName: Full=Leucine-rich repeat-containing protein 44;
GN   Name=LRRIQ3; Synonyms=LRRC44;
//
ID   LRIQ4_HUMAN             Reviewed;         560 AA.
AC   A6NIV6;
DE   RecName: Full=Leucine-rich repeat and IQ domain-containing protein 4;
DE   AltName: Full=Leucine-rich repeat-containing protein 64;
GN   Name=LRRIQ4; Synonyms=LRRC64;
//
ID   LRIT1_HUMAN             Reviewed;         623 AA.
AC   Q9P2V4; Q0QD41; Q9Y4N7;
DE   RecName: Full=Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1;
DE   AltName: Full=Leucine-rich repeat-containing protein 21;
DE   AltName: Full=Photoreceptor-associated LRR superfamily protein;
DE   AltName: Full=Retina-specific protein PAL;
DE   Flags: Precursor;
GN   Name=LRIT1; Synonyms=LRRC21, PAL;
//
ID   LRIT2_HUMAN             Reviewed;         550 AA.
AC   A6NDA9; B7ZME6;
DE   RecName: Full=Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2;
DE   AltName: Full=Leucine-rich repeat-containing protein 22;
DE   Flags: Precursor;
GN   Name=LRIT2; Synonyms=LRRC22;
//
ID   LRIT3_HUMAN             Reviewed;         679 AA.
AC   Q3SXY7; C9J1C2; Q6ZTG1;
DE   RecName: Full=Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=LRIT3;
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.
//
ID   LRMP_HUMAN              Reviewed;         555 AA.
AC   Q12912; A0AVM2; B4E077; Q8N301;
DE   RecName: Full=Lymphoid-restricted membrane protein;
DE   AltName: Full=Protein Jaw1;
DE   Contains:
DE     RecName: Full=Processed lymphoid-restricted membrane protein;
GN   Name=LRMP; Synonyms=JAW1;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   GO; GO:0006906; P:vesicle fusion; TAS:ProtInc.
DR   GO; GO:0006903; P:vesicle targeting; TAS:ProtInc.
//
ID   LRN4L_HUMAN             Reviewed;         238 AA.
AC   Q8ND94; A8K5L9;
DE   RecName: Full=LRRN4 C-terminal-like protein;
DE   Flags: Precursor;
GN   Name=LRRN4CL; ORFNames=UNQ728/PRO1410;
//
ID   LRP10_HUMAN             Reviewed;         713 AA.
AC   Q7Z4F1; A8K4R5; D3DS31; O95882; Q14CK7; Q86T02; Q8NCZ4; Q9HC42;
AC   Q9UG33;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 10;
DE            Short=LRP-10;
DE   Flags: Precursor;
GN   Name=LRP10; ORFNames=MSTP087, SP220, UNQ389/PRO724;
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
//
ID   LRP11_HUMAN             Reviewed;         500 AA.
AC   Q86VZ4; Q5VYC0; Q96SN6;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 11;
DE            Short=LRP-11;
DE   Flags: Precursor;
GN   Name=LRP11;
//
ID   LRP12_HUMAN             Reviewed;         859 AA.
AC   Q9Y561; A8K137; B4DRQ2;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 12;
DE            Short=LRP-12;
DE   AltName: Full=Suppressor of tumorigenicity 7 protein;
DE   Flags: Precursor;
GN   Name=LRP12; Synonyms=ST7;
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:GOC.
DR   GO; GO:0040008; P:regulation of growth; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   LRP1B_HUMAN             Reviewed;        4599 AA.
AC   Q9NZR2; Q8WY29; Q8WY30; Q8WY31;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 1B;
DE            Short=LRP-1B;
DE   AltName: Full=Low-density lipoprotein receptor-related protein-deleted in tumor;
DE            Short=LRP-DIT;
DE   Flags: Precursor;
GN   Name=LRP1B; Synonyms=LRPDIT;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; TAS:ProtInc.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
//
ID   LRP1_HUMAN              Reviewed;        4544 AA.
AC   Q07954; Q2PP12; Q8IVG8;
DE   RecName: Full=Prolow-density lipoprotein receptor-related protein 1;
DE            Short=LRP-1;
DE   AltName: Full=Alpha-2-macroglobulin receptor;
DE            Short=A2MR;
DE   AltName: Full=Apolipoprotein E receptor;
DE            Short=APOER;
DE   AltName: CD_antigen=CD91;
DE   Contains:
DE     RecName: Full=Low-density lipoprotein receptor-related protein 1 85 kDa subunit;
DE              Short=LRP-85;
DE   Contains:
DE     RecName: Full=Low-density lipoprotein receptor-related protein 1 515 kDa subunit;
DE              Short=LRP-515;
DE   Contains:
DE     RecName: Full=Low-density lipoprotein receptor-related protein 1 intracellular domain;
DE              Short=LRPICD;
DE   Flags: Precursor;
GN   Name=LRP1; Synonyms=A2MR, APR;
DR   GO; GO:0034185; F:apolipoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0070325; F:lipoprotein particle receptor binding; IC:BHF-UCL.
DR   GO; GO:0042954; F:lipoprotein transporter activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0035909; P:aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0043277; P:apoptotic cell clearance; ISS:BHF-UCL.
DR   GO; GO:0097242; P:beta-amyloid clearance; TAS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0042953; P:lipoprotein transport; NAS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:2000587; P:negative regulation of platelet-derived growth factor receptor-beta signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; ISS:BHF-UCL.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; ISS:BHF-UCL.
DR   GO; GO:0032370; P:positive regulation of lipid transport; ISS:BHF-UCL.
DR   GO; GO:0051222; P:positive regulation of protein transport; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0032374; P:regulation of cholesterol transport; ISS:BHF-UCL.
DR   GO; GO:0032429; P:regulation of phospholipase A2 activity; ISS:BHF-UCL.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
//
ID   LRP2_HUMAN              Reviewed;        4655 AA.
AC   P98164; O00711; Q16215;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 2;
DE            Short=LRP-2;
DE   AltName: Full=Glycoprotein 330;
DE            Short=gp330;
DE   AltName: Full=Megalin;
DE   Flags: Precursor;
GN   Name=LRP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0042359; P:vitamin D metabolic process; TAS:Reactome.
//
ID   LRP3_HUMAN              Reviewed;         770 AA.
AC   O75074; B3KQD6; B4DKF2;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 3;
DE            Short=LRP-3;
DE   AltName: Full=105 kDa low-density lipoprotein receptor-related protein;
DE            Short=hLRp105;
DE   Flags: Precursor;
GN   Name=LRP3;
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
//
ID   LRP4_HUMAN              Reviewed;        1905 AA.
AC   O75096; B2RN39; Q4AC85; Q5KTZ5;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 4;
DE            Short=LRP-4;
DE   AltName: Full=Multiple epidermal growth factor-like domains 7;
DE   Flags: Precursor;
GN   Name=LRP4; Synonyms=KIAA0816, LRP10, MEGF7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProt.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:UniProt.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProt.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IDA:UniProt.
DR   GO; GO:0060173; P:limb development; IDA:UniProt.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; ISS:UniProt.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030279; P:negative regulation of ossification; IMP:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:1901631; P:positive regulation of presynaptic membrane organization; ISS:UniProt.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:UniProt.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:UniProt.
DR   GO; GO:0051290; P:protein heterotetramerization; ISS:UniProt.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; ISS:UniProt.
DR   GO; GO:0050808; P:synapse organization; ISS:UniProt.
DR   GO; GO:0051124; P:synaptic growth at neuromuscular junction; ISS:UniProt.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   LRP5L_HUMAN             Reviewed;         252 AA.
AC   A4QPB2; B0QYF3; B0QYF4; B2RPI5;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 5-like protein;
DE            Short=LRP-5-like;
GN   Name=LRP5L;
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0044332; P:Wnt signaling pathway involved in dorsal/ventral axis specification; IBA:RefGenome.
//
ID   LRP5_HUMAN              Reviewed;        1615 AA.
AC   O75197; Q96TD6; Q9UES7; Q9UP66;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 5;
DE            Short=LRP-5;
DE   Flags: Precursor;
GN   Name=LRP5; Synonyms=LR3, LRP7;
DR   GO; GO:0015026; F:coreceptor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0060612; P:adipose tissue development; IMP:BHF-UCL.
DR   GO; GO:0060033; P:anatomical structure regression; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IBA:RefGenome.
DR   GO; GO:1902262; P:apoptotic process involved in patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0048539; P:bone marrow development; IMP:BHF-UCL.
DR   GO; GO:0060349; P:bone morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0046849; P:bone remodeling; IBA:RefGenome.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0060764; P:cell-cell signaling involved in mammary gland development; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IBA:RefGenome.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IBA:RefGenome.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IBA:RefGenome.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0035426; P:extracellular matrix-cell signaling; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IBA:RefGenome.
DR   GO; GO:0006007; P:glucose catabolic process; IMP:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IMP:BHF-UCL.
DR   GO; GO:0002076; P:osteoblast development; IBA:RefGenome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:BHF-UCL.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:BHF-UCL.
DR   GO; GO:0046850; P:regulation of bone remodeling; IEA:Ensembl.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IBA:RefGenome.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IMP:BHF-UCL.
DR   GO; GO:0061304; P:retinal blood vessel morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0044332; P:Wnt signaling pathway involved in dorsal/ventral axis specification; IDA:BHF-UCL.
//
ID   LRP6_HUMAN              Reviewed;        1613 AA.
AC   O75581; Q17RZ2;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 6;
DE            Short=LRP-6;
DE   Flags: Precursor;
GN   Name=LRP6;
DR   GO; GO:0034185; F:apolipoprotein binding; IBA:RefGenome.
DR   GO; GO:0071936; F:coreceptor activity involved in Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0005109; F:frizzled binding; IPI:BHF-UCL.
DR   GO; GO:0019210; F:kinase inhibitor activity; IMP:BHF-UCL.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0019534; F:toxin transporter activity; IMP:BHF-UCL.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IBA:RefGenome.
DR   GO; GO:0090245; P:axis elongation involved in somitogenesis; IBA:RefGenome.
DR   GO; GO:0060349; P:bone morphogenesis; IBA:RefGenome.
DR   GO; GO:0046849; P:bone remodeling; IBA:RefGenome.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0061310; P:canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development; IEA:Ensembl.
DR   GO; GO:0044335; P:canonical Wnt signaling pathway involved in neural crest cell differentiation; IC:BHF-UCL.
DR   GO; GO:0061324; P:canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation; IEA:Ensembl.
DR   GO; GO:0044340; P:canonical Wnt signaling pathway involved in regulation of cell proliferation; IC:BHF-UCL.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0071397; P:cellular response to cholesterol; IMP:BHF-UCL.
DR   GO; GO:0021587; P:cerebellum morphogenesis; IBA:RefGenome.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IBA:RefGenome.
DR   GO; GO:0060026; P:convergent extension; IBA:RefGenome.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IBA:RefGenome.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IBA:RefGenome.
DR   GO; GO:0009880; P:embryonic pattern specification; IBA:RefGenome.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IBA:RefGenome.
DR   GO; GO:0035261; P:external genitalia morphogenesis; IBA:RefGenome.
DR   GO; GO:0060325; P:face morphogenesis; IBA:RefGenome.
DR   GO; GO:0021861; P:forebrain radial glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0021943; P:formation of radial glial scaffolds; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IBA:RefGenome.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0060596; P:mammary placode formation; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IBA:RefGenome.
DR   GO; GO:0030917; P:midbrain-hindbrain boundary development; IBA:RefGenome.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:2000151; P:negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:2000162; P:negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis; IEA:Ensembl.
DR   GO; GO:2000168; P:negative regulation of planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:2000164; P:negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:2000166; P:negative regulation of planar cell polarity pathway involved in pericardium morphogenesis; IEA:Ensembl.
DR   GO; GO:2000149; P:negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0071901; P:negative regulation of protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0034392; P:negative regulation of smooth muscle cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0014033; P:neural crest cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0014029; P:neural crest formation; IDA:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; IBA:RefGenome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IBA:RefGenome.
DR   GO; GO:0060021; P:palate development; IBA:RefGenome.
DR   GO; GO:0003344; P:pericardium morphogenesis; IBA:RefGenome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IMP:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:2000055; P:positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; IDA:BHF-UCL.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; IBA:RefGenome.
DR   GO; GO:0090118; P:receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport; IBA:RefGenome.
DR   GO; GO:0060284; P:regulation of cell development; IEA:Ensembl.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IBA:RefGenome.
DR   GO; GO:0030278; P:regulation of ossification; IBA:RefGenome.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IBA:RefGenome.
DR   GO; GO:0021794; P:thalamus development; IBA:RefGenome.
DR   GO; GO:1901998; P:toxin transport; IMP:GOC.
DR   GO; GO:0060535; P:trachea cartilage morphogenesis; IBA:RefGenome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0044332; P:Wnt signaling pathway involved in dorsal/ventral axis specification; IDA:BHF-UCL.
DR   GO; GO:0021874; P:Wnt signaling pathway involved in forebrain neuroblast division; IEA:Ensembl.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IBA:RefGenome.
//
ID   LRP8_HUMAN              Reviewed;         963 AA.
AC   Q14114; B1AMT6; B1AMT7; B1AMT8; O14968; Q86V27; Q99876; Q9BR78;
DE   RecName: Full=Low-density lipoprotein receptor-related protein 8;
DE            Short=LRP-8;
DE   AltName: Full=Apolipoprotein E receptor 2;
DE   Flags: Precursor;
GN   Name=LRP8; Synonyms=APOER2;
DR   GO; GO:0034185; F:apolipoprotein binding; IC:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0038025; F:reelin receptor activity; ISS:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0030229; F:very-low-density lipoprotein particle receptor activity; IDA:BHF-UCL.
DR   GO; GO:0021541; P:ammon gyrus development; ISS:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071397; P:cellular response to cholesterol; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IDA:UniProtKB.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:1900006; P:positive regulation of dendrite development; ISS:BHF-UCL.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; ISS:BHF-UCL.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:GOC.
DR   GO; GO:0038026; P:reelin-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0050804; P:regulation of synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LRR70_HUMAN             Reviewed;         622 AA.
AC   Q7Z2Q7; Q6ZWI5;
DE   RecName: Full=Leucine-rich repeat-containing protein 70;
DE   AltName: Full=Synleurin;
DE   Flags: Precursor;
GN   Name=LRRC70; ORFNames=UNQ1891/PRO4337;
//
ID   LRR3C_HUMAN             Reviewed;         275 AA.
AC   A6NJW4;
DE   RecName: Full=Leucine-rich repeat-containing protein 3C;
DE   Flags: Precursor;
GN   Name=LRRC3C;
//
ID   LRRC1_HUMAN             Reviewed;         524 AA.
AC   Q9BTT6; Q5TGN3; Q9HAC0; Q9NVF1;
DE   RecName: Full=Leucine-rich repeat-containing protein 1;
DE   AltName: Full=LANO adapter protein;
DE   AltName: Full=LAP and no PDZ protein;
GN   Name=LRRC1; Synonyms=LANO;
//
ID   LRRC3_HUMAN             Reviewed;         257 AA.
AC   Q9BY71; Q0VDJ2;
DE   RecName: Full=Leucine-rich repeat-containing protein 3;
DE   Flags: Precursor;
GN   Name=LRRC3; Synonyms=C21orf102, LRRC3A; ORFNames=UNQ9233/PRO31982;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LRRC2_HUMAN             Reviewed;         371 AA.
AC   Q9BYS8; B2RDQ7; Q96LT5;
DE   RecName: Full=Leucine-rich repeat-containing protein 2;
GN   Name=LRRC2;
//
ID   LRRC4_HUMAN             Reviewed;         653 AA.
AC   Q9HBW1; A4D0Y9; Q14DU9; Q6ZMI8; Q96A85;
DE   RecName: Full=Leucine-rich repeat-containing protein 4;
DE   AltName: Full=Brain tumor-associated protein BAG;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 14 protein;
DE   AltName: Full=Netrin-G2 ligand;
DE            Short=NGL-2;
DE   Flags: Precursor;
GN   Name=LRRC4; Synonyms=BAG; ORFNames=NAG14, UNQ554/PRO1111;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LRRC7_HUMAN             Reviewed;        1537 AA.
AC   Q96NW7; Q5VXC2; Q5VXC3; Q68D07; Q86VE8; Q8WX20; Q9P2I2;
DE   RecName: Full=Leucine-rich repeat-containing protein 7;
DE   AltName: Full=Densin-180;
DE            Short=Densin;
DE   AltName: Full=Protein LAP1;
GN   Name=LRRC7; Synonyms=KIAA1365, LAP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LRRC9_HUMAN             Reviewed;        1453 AA.
AC   Q6ZRR7;
DE   RecName: Full=Leucine-rich repeat-containing protein 9;
GN   Name=LRRC9;
//
ID   LRRD1_HUMAN             Reviewed;         860 AA.
AC   A4D1F6; B7ZMM9; Q49AT9;
DE   RecName: Full=Leucine-rich repeat and death domain-containing protein 1;
GN   Name=LRRD1;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   LRRDN_HUMAN             Reviewed;         244 AA.
AC   Q9UFM2;
DE   RecName: Full=Putative uncharacterized protein LRRC3DN;
DE   AltName: Full=LRRC3 downstream neighbor protein;
GN   Name=LRRC3DN; Synonyms=C21orf30;
//
ID   LRRF1_HUMAN             Reviewed;         808 AA.
AC   Q32MZ4; E9PGZ2; O75766; O75799; Q32MZ5; Q53T49; Q6PKG2; Q9Y607;
DE   RecName: Full=Leucine-rich repeat flightless-interacting protein 1;
DE            Short=LRR FLII-interacting protein 1;
DE   AltName: Full=GC-binding factor 2;
DE   AltName: Full=TAR RNA-interacting protein;
GN   Name=LRRFIP1; Synonyms=GCF2, TRIP;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LRRK1_HUMAN             Reviewed;        2015 AA.
AC   Q38SD2; Q6NVH5; Q6NYC0; Q6ZNL9; Q6ZNM9; Q96JN5; Q9H5S3;
DE   RecName: Full=Leucine-rich repeat serine/threonine-protein kinase 1;
DE            EC=2.7.11.1;
GN   Name=LRRK1; Synonyms=KIAA1790;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   LRRF2_HUMAN             Reviewed;         721 AA.
AC   Q9Y608; A8K649; Q68CV3; Q9NXH5;
DE   RecName: Full=Leucine-rich repeat flightless-interacting protein 2;
DE            Short=LRR FLII-interacting protein 2;
GN   Name=LRRFIP2;
DR   GO; GO:0030275; F:LRR domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   LRRN1_HUMAN             Reviewed;         716 AA.
AC   Q6UXK5; Q3LID5; Q8IYV5; Q9H8V1; Q9P231;
DE   RecName: Full=Leucine-rich repeat neuronal protein 1;
DE   AltName: Full=Neuronal leucine-rich repeat protein 1;
DE            Short=NLRR-1;
DE   Flags: Precursor;
GN   Name=LRRN1; Synonyms=KIAA1497; ORFNames=Nbla10449, UNQ693/PRO1338;
//
ID   LRRK2_HUMAN             Reviewed;        2527 AA.
AC   Q5S007; A6NJU2; Q6ZS50; Q8NCX9;
DE   RecName: Full=Leucine-rich repeat serine/threonine-protein kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=Dardarin;
GN   Name=LRRK2; Synonyms=PARK8;
DR   GuidetoPHARMACOLOGY; 2059; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044325; F:ion channel binding; IPI:UniProtKB.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; IPI:ParkinsonsUK-UCL.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0015631; F:tubulin binding; IDA:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:GOC.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.
DR   GO; GO:0035640; P:exploration behavior; IMP:BHF-UCL.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IDA:MGI.
DR   GO; GO:1902823; P:negative regulation of late endosome to lysosome transport; TAS:ParkinsonsUK-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; IMP:ParkinsonsUK-UCL.
DR   GO; GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.
DR   GO; GO:0070997; P:neuron death; IMP:BHF-UCL.
DR   GO; GO:0021772; P:olfactory bulb development; IMP:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:2000172; P:regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.
DR   GO; GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.
DR   GO; GO:0051900; P:regulation of mitochondrial depolarization; IMP:ParkinsonsUK-UCL.
DR   GO; GO:1902692; P:regulation of neuroblast proliferation; IMP:ParkinsonsUK-UCL.
DR   GO; GO:1901214; P:regulation of neuron death; IMP:ParkinsonsUK-UCL.
DR   GO; GO:0014041; P:regulation of neuron maturation; IMP:BHF-UCL.
DR   GO; GO:2000300; P:regulation of synaptic vesicle exocytosis; IMP:ParkinsonsUK-UCL.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL.
//
ID   LRRN2_HUMAN             Reviewed;         713 AA.
AC   O75325; B2R624; Q5T0Y0; Q6UXM0; Q8N182;
DE   RecName: Full=Leucine-rich repeat neuronal protein 2;
DE   AltName: Full=Glioma amplified on chromosome 1 protein;
DE   AltName: Full=Leucine-rich repeat neuronal protein 5;
DE   Flags: Precursor;
GN   Name=LRRN2; Synonyms=GAC1, LRRN5; ORFNames=UNQ256/PRO293;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LRRN3_HUMAN             Reviewed;         708 AA.
AC   Q9H3W5; O43377; Q6I9V8; Q8IYQ6;
DE   RecName: Full=Leucine-rich repeat neuronal protein 3;
DE   AltName: Full=Neuronal leucine-rich repeat protein 3;
DE            Short=NLRR-3;
DE   Flags: Precursor;
GN   Name=LRRN3; ORFNames=Nbla10363, UNQ194/PRO220;
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
//
ID   LRRN4_HUMAN             Reviewed;         740 AA.
AC   Q8WUT4; A8K258; Q5JWV6; Q9H419;
DE   RecName: Full=Leucine-rich repeat neuronal protein 4;
DE   AltName: Full=Neuronal leucine-rich repeat protein 4;
DE            Short=NLRR-4;
DE   Flags: Precursor;
GN   Name=LRRN4; Synonyms=C20orf75;
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   LRRT1_HUMAN             Reviewed;         522 AA.
AC   Q86UE6; A8K397; D6W5K1; Q96DN1;
DE   RecName: Full=Leucine-rich repeat transmembrane neuronal protein 1;
DE   Flags: Precursor;
GN   Name=LRRTM1; ORFNames=UNQ675/PRO1309;
DR   GO; GO:0035640; P:exploration behavior; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0035418; P:protein localization to synapse; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
//
ID   LRRT2_HUMAN             Reviewed;         516 AA.
AC   O43300; A0AVL3; A8K4U9; B7ZLN8; Q7L770;
DE   RecName: Full=Leucine-rich repeat transmembrane neuronal protein 2;
DE   AltName: Full=Leucine-rich repeat neuronal 2 protein;
DE   Flags: Precursor;
GN   Name=LRRTM2; Synonyms=KIAA0416, LRRN2;
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
//
ID   LRRT3_HUMAN             Reviewed;         581 AA.
AC   Q86VH5; A8K2A3; Q2NKX7; Q6N0A3;
DE   RecName: Full=Leucine-rich repeat transmembrane neuronal protein 3;
DE   Flags: Precursor;
GN   Name=LRRTM3; ORFNames=UNQ803/PRO1693;
DR   GO; GO:1902004; P:positive regulation of beta-amyloid formation; IMP:MGI.
//
ID   LRRT4_HUMAN             Reviewed;         590 AA.
AC   Q86VH4; Q4FZ98; Q6UXJ7;
DE   RecName: Full=Leucine-rich repeat transmembrane neuronal protein 4;
DE   Flags: Precursor;
GN   Name=LRRTM4; ORFNames=UNQ3075/PRO9907;
//
ID   LRSM1_HUMAN             Reviewed;         723 AA.
AC   Q6UWE0; Q5VVV0; Q8NB40; Q96GT5; Q96MX5; Q96MZ7;
DE   RecName: Full=E3 ubiquitin-protein ligase LRSAM1;
DE            EC=6.3.2.-;
DE   AltName: Full=Leucine-rich repeat and sterile alpha motif-containing protein 1;
DE   AltName: Full=Tsg101-associated ligase;
DE            Short=hTAL;
GN   Name=LRSAM1; Synonyms=TAL; ORFNames=UNQ6496/PRO21356;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0070086; P:ubiquitin-dependent endocytosis; IDA:UniProtKB.
DR   GO; GO:0046755; P:viral budding; IMP:UniProtKB.
//
ID   LRTM1_HUMAN             Reviewed;         345 AA.
AC   Q9HBL6; Q8IUU2;
DE   RecName: Full=Leucine-rich repeat and transmembrane domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=LRTM1; ORFNames=HT017;
//
ID   LRTM2_HUMAN             Reviewed;         370 AA.
AC   Q8N967; A7E2U6;
DE   RecName: Full=Leucine-rich repeat and transmembrane domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=LRTM2;
//
ID   LRWD1_HUMAN             Reviewed;         647 AA.
AC   Q9UFC0; A8K4K2; B2R9G2; Q8N0T9; Q8WV43; Q96GJ2;
DE   RecName: Full=Leucine-rich repeat and WD repeat-containing protein 1;
DE   AltName: Full=Centromere protein 33;
DE            Short=CENP-33;
DE   AltName: Full=Origin recognition complex-associated protein;
DE            Short=ORC-associated protein;
DE            Short=ORCA;
GN   Name=LRWD1; Synonyms=CENP33, ORCA;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; IMP:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:UniProtKB.
DR   GO; GO:0071169; P:establishment of protein localization to chromatin; IDA:UniProtKB.
//
ID   LS14A_HUMAN             Reviewed;         463 AA.
AC   Q8ND56; Q76LX7; Q96AR3; Q96K73; Q96SN5; Q9UFR3;
DE   RecName: Full=Protein LSM14 homolog A;
DE   AltName: Full=Protein FAM61A;
DE   AltName: Full=Protein SCD6 homolog;
DE   AltName: Full=Putative alpha-synuclein-binding protein;
DE            Short=AlphaSNBP;
DE   AltName: Full=RNA-associated protein 55A;
DE            Short=hRAP55;
DE            Short=hRAP55A;
GN   Name=LSM14A; Synonyms=C19orf13, FAM61A, RAP55, RAP55A;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0039529; P:RIG-I signaling pathway; IEA:Ensembl.
//
ID   LS14B_HUMAN             Reviewed;         385 AA.
AC   Q9BX40; Q6PFW8; Q96LH8;
DE   RecName: Full=Protein LSM14 homolog B;
DE   AltName: Full=Protein FAM61B;
DE   AltName: Full=RNA-associated protein 55B;
DE            Short=hRAP55B;
GN   Name=LSM14B; Synonyms=C20orf40, FAM61B, RAP55B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   LSAMP_HUMAN             Reviewed;         338 AA.
AC   Q13449; Q8IV49;
DE   RecName: Full=Limbic system-associated membrane protein;
DE            Short=LSAMP;
DE   AltName: Full=IgLON family member 3;
DE   Flags: Precursor;
GN   Name=LSAMP; Synonyms=IGLON3, LAMP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   LSG1_HUMAN              Reviewed;         658 AA.
AC   Q9H089; A0JLT4; A0PJK3; A6NI18; Q7L9H8; Q9NUK8;
DE   RecName: Full=Large subunit GTPase 1 homolog;
DE            Short=hLsg1;
DE            EC=3.6.1.-;
GN   Name=LSG1;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0051168; P:nuclear export; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
//
ID   LSHB_HUMAN              Reviewed;         141 AA.
AC   P01229; Q9UDI0;
DE   RecName: Full=Lutropin subunit beta;
DE            Short=Lutropin beta chain;
DE   AltName: Full=Luteinizing hormone subunit beta;
DE            Short=LH-B;
DE            Short=LSH-B;
DE            Short=LSH-beta;
DE   Flags: Precursor;
GN   Name=LHB;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0006701; P:progesterone biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   LSHR_HUMAN              Reviewed;         699 AA.
AC   P22888; Q14751; Q15996; Q9UEW9;
DE   RecName: Full=Lutropin-choriogonadotropic hormone receptor;
DE            Short=LH/CG-R;
DE   AltName: Full=Luteinizing hormone receptor;
DE            Short=LHR;
DE            Short=LSH-R;
DE   Flags: Precursor;
GN   Name=LHCGR; Synonyms=LCGR, LGR2, LHRHR;
DR   GuidetoPHARMACOLOGY; 254; -.
DR   GO; GO:0038106; F:choriogonadotropin hormone binding; ISS:BHF-UCL.
DR   GO; GO:0035472; F:choriogonadotropin hormone receptor activity; ISS:BHF-UCL.
DR   GO; GO:0004964; F:luteinizing hormone receptor activity; IEA:InterPro.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; ISS:BHF-UCL.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; ISS:BHF-UCL.
DR   GO; GO:0046544; P:development of secondary male sexual characteristics; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0030539; P:male genitalia development; TAS:ProtInc.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; ISS:BHF-UCL.
DR   GO; GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0090030; P:regulation of steroid hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0072520; P:seminiferous tubule development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0060065; P:uterus development; IEA:Ensembl.
//
ID   LSM11_HUMAN             Reviewed;         360 AA.
AC   P83369; A0AVQ1; Q7Z7P0; Q8N975;
DE   RecName: Full=U7 snRNA-associated Sm-like protein LSm11;
GN   Name=LSM11;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071209; F:U7 snRNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006398; P:histone mRNA 3'-end processing; ISS:UniProtKB.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000084; P:mitotic S phase; IMP:UniProtKB.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   LSM10_HUMAN             Reviewed;         123 AA.
AC   Q969L4;
DE   RecName: Full=U7 snRNA-associated Sm-like protein LSm10;
GN   Name=LSM10;
DR   GO; GO:0071208; F:histone pre-mRNA DCP binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000084; P:mitotic S phase; IMP:UniProtKB.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   LSM12_HUMAN             Reviewed;         195 AA.
AC   Q3MHD2; Q86YB1; Q96NL5;
DE   RecName: Full=Protein LSM12 homolog;
GN   Name=LSM12;
//
ID   LSM2_HUMAN              Reviewed;          95 AA.
AC   Q9Y333; Q6FGG1;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm2;
DE   AltName: Full=Protein G7b;
DE   AltName: Full=Small nuclear ribonuclear protein D homolog;
DE   AltName: Full=snRNP core Sm-like protein Sm-x5;
GN   Name=LSM2; Synonyms=C6orf28, G7B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017070; F:U6 snRNA binding; NAS:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   LSM3_HUMAN              Reviewed;         102 AA.
AC   P62310; Q6IAH0; Q9Y4Z1;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm3;
GN   Name=LSM3; ORFNames=MDS017;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   LSM1_HUMAN              Reviewed;         133 AA.
AC   O15116; B2R5E6;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm1;
DE   AltName: Full=Cancer-associated Sm-like;
DE   AltName: Full=Small nuclear ribonuclear CaSm;
GN   Name=LSM1; Synonyms=CASM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   LSM4_HUMAN              Reviewed;         139 AA.
AC   Q9Y4Z0;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm4;
DE   AltName: Full=Glycine-rich protein;
DE            Short=GRP;
GN   Name=LSM4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   LSM5_HUMAN              Reviewed;          91 AA.
AC   Q9Y4Y9;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm5;
GN   Name=LSM5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   LSM6_HUMAN              Reviewed;          80 AA.
AC   P62312; Q4W5J5; Q9Y4Y8;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm6;
GN   Name=LSM6;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   LSM7_HUMAN              Reviewed;         103 AA.
AC   Q9UK45;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm7;
GN   Name=LSM7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017070; F:U6 snRNA binding; NAS:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   LSM8_HUMAN              Reviewed;          96 AA.
AC   O95777;
DE   RecName: Full=U6 snRNA-associated Sm-like protein LSm8;
GN   Name=LSM8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017070; F:U6 snRNA binding; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   LSMD1_HUMAN             Reviewed;         125 AA.
AC   Q9BRA0; Q8N4M0;
DE   RecName: Full=N-alpha-acetyltransferase 38, NatC auxiliary subunit;
DE   AltName: Full=LSM domain-containing protein 1;
DE   AltName: Full=Phosphonoformate immuno-associated protein 2;
GN   Name=NAA38; Synonyms=LSMD1, MAK31, PFAAP2;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
//
ID   LSME1_HUMAN             Reviewed;         131 AA.
AC   Q8N8F7; Q49AR6;
DE   RecName: Full=Leucine-rich single-pass membrane protein 1;
GN   Name=LSMEM1; Synonyms=C7orf53;
//
ID   LSME2_HUMAN             Reviewed;         164 AA.
AC   Q8N112;
DE   RecName: Full=Leucine-rich single-pass membrane protein 2;
GN   Name=LSMEM2; Synonyms=C3orf45;
//
ID   LSP1_HUMAN              Reviewed;         339 AA.
AC   P33241; B3KPP1; B3KRR6; E9PBV6; E9PFP3; Q16096; Q53H48; Q6FHM3;
AC   Q9BUY8;
DE   RecName: Full=Lymphocyte-specific protein 1;
DE   AltName: Full=47 kDa actin-binding protein;
DE   AltName: Full=52 kDa phosphoprotein;
DE            Short=pp52;
DE   AltName: Full=Lymphocyte-specific antigen WP34;
GN   Name=LSP1; Synonyms=WP34;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   LSR_HUMAN               Reviewed;         649 AA.
AC   Q86X29; A6NDW3; E9PHD4; O00112; O00426; Q6ZT80; Q8NBM0; Q9BT33;
AC   Q9UQL3;
DE   RecName: Full=Lipolysis-stimulated lipoprotein receptor;
GN   Name=LSR; Synonyms=LISCH;
DR   GO; GO:0009790; P:embryo development; ISS:HGNC.
DR   GO; GO:0001889; P:liver development; ISS:HGNC.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
//
ID   LST1_HUMAN              Reviewed;          97 AA.
AC   O00453; B0S8E0; B0S8E1; B0S8E5; O00452; O00454; Q13669; Q2HNT3;
AC   Q5HYS9; Q5SP24; Q5STA5; Q5STA6; Q5STA7; Q5STA8; Q5STW6; Q9UJR5;
AC   Q9UJR6; Q9UJR7; Q9UJR8; Q9UJS1;
DE   RecName: Full=Leukocyte-specific transcript 1 protein;
DE   AltName: Full=Protein B144;
GN   Name=LST1; Synonyms=B144;
DR   GO; GO:0009653; P:anatomical structure morphogenesis; NAS:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0016358; P:dendrite development; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050672; P:negative regulation of lymphocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
//
ID   LST2_HUMAN              Reviewed;         887 AA.
AC   Q9HCC9; B2RP83; B3KX50; B7Z1Q7; B7Z2G9; B7Z2M2; B7ZB19; E9PB54;
AC   E9PB64; E9PG77; Q7Z6J3;
DE   RecName: Full=Lateral signaling target protein 2 homolog;
DE            Short=hLst2;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 28;
GN   Name=ZFYVE28; Synonyms=KIAA1643, LST2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IMP:UniProtKB.
//
ID   LST8_HUMAN              Reviewed;         326 AA.
AC   Q9BVC4; B3KMM4; B4DY00; D3DU88; Q5M800; Q86Y18; Q8WUI5; Q9HA66;
AC   Q9UJV6;
DE   RecName: Full=Target of rapamycin complex subunit LST8;
DE            Short=TORC subunit LST8;
DE   AltName: Full=G protein beta subunit-like;
DE            Short=Gable;
DE            Short=Protein GbetaL;
DE   AltName: Full=Mammalian lethal with SEC13 protein 8;
DE            Short=mLST8;
GN   Name=MLST8; Synonyms=GBL, LST8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   LT4R1_HUMAN             Reviewed;         352 AA.
AC   Q15722; Q13305; Q53XV5; Q92641; Q9BSU5;
DE   RecName: Full=Leukotriene B4 receptor 1;
DE            Short=LTB4-R 1;
DE            Short=LTB4-R1;
DE   AltName: Full=Chemoattractant receptor-like 1;
DE   AltName: Full=G-protein coupled receptor 16;
DE   AltName: Full=P2Y purinoceptor 7;
DE            Short=P2Y7;
GN   Name=LTB4R; Synonyms=BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7;
DR   GuidetoPHARMACOLOGY; 267; -.
DR   GO; GO:0001632; F:leukotriene B4 receptor activity; IEA:Ensembl.
DR   GO; GO:0004974; F:leukotriene receptor activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   LT4R2_HUMAN             Reviewed;         389 AA.
AC   Q9NPC1; Q5KU28; Q9NPE5;
DE   RecName: Full=Leukotriene B4 receptor 2;
DE            Short=LTB4-R 2;
DE            Short=LTB4-R2;
DE   AltName: Full=LTB4 receptor JULF2;
DE   AltName: Full=Leukotriene B4 receptor BLT2;
DE   AltName: Full=Seven transmembrane receptor BLTR2;
GN   Name=LTB4R2; Synonyms=BLT2R, BLTR2;
DR   GuidetoPHARMACOLOGY; 268; -.
DR   GO; GO:0004974; F:leukotriene receptor activity; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; TAS:ProtInc.
//
ID   LTBP1_HUMAN             Reviewed;        1721 AA.
AC   Q14766; A1L3V1; P22064; Q53SD8; Q53SF3; Q53SG1; Q59HF7; Q8TD95;
DE   RecName: Full=Latent-transforming growth factor beta-binding protein 1;
DE            Short=LTBP-1;
DE   AltName: Full=Transforming growth factor beta-1-binding protein 1;
DE            Short=TGF-beta1-BP-1;
DE   Flags: Precursor;
GN   Name=LTBP1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IPI:UniProt.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0035583; P:sequestering of TGFbeta in extracellular matrix; TAS:BHF-UCL.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; NAS:GOC.
//
ID   LTBP2_HUMAN             Reviewed;        1821 AA.
AC   Q14767; Q99907; Q9NS51;
DE   RecName: Full=Latent-transforming growth factor beta-binding protein 2;
DE            Short=LTBP-2;
DE   Flags: Precursor;
GN   Name=LTBP2; Synonyms=C14orf141, LTBP3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009306; P:protein secretion; TAS:ProtInc.
DR   GO; GO:0006605; P:protein targeting; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
//
ID   LTBP3_HUMAN             Reviewed;        1303 AA.
AC   Q9NS15; O15107; Q96HB9; Q9H7K2; Q9UFN4;
DE   RecName: Full=Latent-transforming growth factor beta-binding protein 3;
DE            Short=LTBP-3;
DE   Flags: Precursor;
GN   Name=LTBP3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IPI:UniProt.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060430; P:lung saccule development; IEA:Ensembl.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IMP:UniProt.
DR   GO; GO:1902462; P:positive regulation of mesenchymal stem cell proliferation; IMP:UniProt.
DR   GO; GO:0036363; P:transforming growth factor beta activation; IMP:UniProt.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   LTBP4_HUMAN             Reviewed;        1624 AA.
AC   Q8N2S1; O00508; O75412; O75413;
DE   RecName: Full=Latent-transforming growth factor beta-binding protein 4;
DE            Short=LTBP-4;
DE   Flags: Precursor;
GN   Name=LTBP4;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0005539; F:glycosaminoglycan binding; NAS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IDA:UniProtKB.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030252; P:growth hormone secretion; TAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IDA:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   LTC4S_HUMAN             Reviewed;         150 AA.
AC   Q16873; Q8N6P0; Q9UC73; Q9UD18;
DE   RecName: Full=Leukotriene C4 synthase;
DE            Short=LTC4 synthase;
DE            EC=4.4.1.20;
DE   AltName: Full=Leukotriene-C(4) synthase;
GN   Name=LTC4S;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IBA:RefGenome.
DR   GO; GO:0004364; F:glutathione transferase activity; IBA:RefGenome.
DR   GO; GO:0004464; F:leukotriene-C4 synthase activity; IDA:MGI.
DR   GO; GO:0008289; F:lipid binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IBA:RefGenome.
DR   GO; GO:0006691; P:leukotriene metabolic process; IDA:MGI.
DR   GO; GO:2001300; P:lipoxin metabolic process; TAS:Reactome.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IBA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LTMD1_HUMAN             Reviewed;         360 AA.
AC   Q6P1Q0; A6NER7; B3KXK7; Q6X2E4; Q6X2E5; Q7L2G9; Q7L690; Q8WXW6;
AC   Q96PK7; Q9BY59; Q9Y3X3;
DE   RecName: Full=LETM1 domain-containing protein 1;
DE   AltName: Full=Cervical cancer 1 proto-oncogene protein p40;
DE   AltName: Full=Cervical cancer proto-oncogene 2 protein;
DE   AltName: Full=HCCR-1;
DE   AltName: Full=HCRR-2;
GN   Name=LETMD1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   LTK_HUMAN               Reviewed;         864 AA.
AC   P29376; A6NNJ8; B4DL89; E9PFX4;
DE   RecName: Full=Leukocyte tyrosine kinase receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=Protein tyrosine kinase 1;
DE   Flags: Precursor;
GN   Name=LTK; Synonyms=TYK1;
DR   GuidetoPHARMACOLOGY; 1838; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
//
ID   LTN1_HUMAN              Reviewed;        1766 AA.
AC   O94822; A6NL41; A7E2D0; B2RTS0; C9J7U3; J3KPL4; Q05C47; Q9H8M4;
AC   Q9NUY5; Q9P0E9;
DE   RecName: Full=E3 ubiquitin-protein ligase listerin;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 160;
DE   AltName: Full=Zinc finger protein 294;
GN   Name=LTN1; Synonyms=C21orf10, C21orf98, KIAA0714, RNF160, ZNF294;
GN   ORFNames=HSPC087;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IEA:Ensembl.
//
ID   LTOR2_HUMAN             Reviewed;         125 AA.
AC   Q9Y2Q5; Q5VY97; Q5VY98; Q5VY99;
DE   RecName: Full=Ragulator complex protein LAMTOR2;
DE   AltName: Full=Endosomal adaptor protein p14;
DE   AltName: Full=Late endosomal/lysosomal Mp1-interacting protein;
DE   AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2;
DE   AltName: Full=Mitogen-activated protein-binding protein-interacting protein;
DE            Short=MAPBP-interacting protein;
DE   AltName: Full=Roadblock domain-containing protein 3;
GN   Name=LAMTOR2; Synonyms=MAPBPIP, ROBLD3; ORFNames=HSPC003;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IMP:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
//
ID   LTOR1_HUMAN             Reviewed;         161 AA.
AC   Q6IAA8; Q8WZ09; Q9NWT0;
DE   RecName: Full=Ragulator complex protein LAMTOR1;
DE   AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1;
DE   AltName: Full=Lipid raft adaptor protein p18;
DE   AltName: Full=Protein associated with DRMs and endosomes;
DE   AltName: Full=p27Kip1-releasing factor from RhoA;
DE            Short=p27RF-Rho;
GN   Name=LAMTOR1; Synonyms=C11orf59, PDRO; ORFNames=PP7157;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IMP:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:UniProtKB.
DR   GO; GO:0032439; P:endosome localization; ISS:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; ISS:UniProtKB.
DR   GO; GO:0032418; P:lysosome localization; ISS:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; ISS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0010874; P:regulation of cholesterol efflux; IMP:UniProtKB.
DR   GO; GO:0010872; P:regulation of cholesterol esterification; IMP:UniProtKB.
DR   GO; GO:0060620; P:regulation of cholesterol import; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0001919; P:regulation of receptor recycling; ISS:UniProtKB.
//
ID   LTOR3_HUMAN             Reviewed;         124 AA.
AC   Q9UHA4; B2R4A1; J3KMX4; Q9H364;
DE   RecName: Full=Ragulator complex protein LAMTOR3;
DE   AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3;
DE   AltName: Full=MEK-binding partner 1;
DE            Short=Mp1;
DE   AltName: Full=Mitogen-activated protein kinase kinase 1-interacting protein 1;
DE   AltName: Full=Mitogen-activated protein kinase scaffold protein 1;
GN   Name=LAMTOR3; Synonyms=MAP2K1IP1, MAPKSP1; ORFNames=PRO2783;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034613; P:cellular protein localization; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
//
ID   LTOR5_HUMAN             Reviewed;          91 AA.
AC   O43504; Q6IBD8;
DE   RecName: Full=Ragulator complex protein LAMTOR5;
DE   AltName: Full=Hepatitis B virus X-interacting protein;
DE            Short=HBV X-interacting protein;
DE            Short=HBX-interacting protein;
DE   AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;
GN   Name=LAMTOR5; Synonyms=HBXIP, XIP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0061462; P:protein localization to lysosome; IMP:UniProtKB.
DR   GO; GO:0008361; P:regulation of cell size; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
//
ID   LTOR4_HUMAN             Reviewed;          99 AA.
AC   Q0VGL1;
DE   RecName: Full=Ragulator complex protein LAMTOR4;
DE   AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4;
DE   Contains:
DE     RecName: Full=Ragulator complex protein LAMTOR4, N-terminally processed;
GN   Name=LAMTOR4; Synonyms=C7orf59;
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0061462; P:protein localization to lysosome; IMP:UniProtKB.
DR   GO; GO:0008361; P:regulation of cell size; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
//
ID   LTV1_HUMAN              Reviewed;         475 AA.
AC   Q96GA3; Q96JX8;
DE   RecName: Full=Protein LTV1 homolog;
GN   Name=LTV1; Synonyms=C6orf93;
//
ID   LUC7L_HUMAN             Reviewed;         371 AA.
AC   Q9NQ29; B8ZZ13; Q96S32; Q9NPH4;
DE   RecName: Full=Putative RNA-binding protein Luc7-like 1;
DE   AltName: Full=Putative SR protein LUC7B1;
DE   AltName: Full=SR+89;
GN   Name=LUC7L; Synonyms=LUC7L1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:InterPro.
DR   GO; GO:0045843; P:negative regulation of striated muscle tissue development; IEA:Ensembl.
//
ID   LUM_HUMAN               Reviewed;         338 AA.
AC   P51884; B2R6R5; Q96QM7;
DE   RecName: Full=Lumican;
DE   AltName: Full=Keratan sulfate proteoglycan lumican;
DE            Short=KSPG lumican;
DE   Flags: Precursor;
GN   Name=LUM; Synonyms=LDC, SLRR2D;
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; NAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0070848; P:response to growth factor; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   LUR1L_HUMAN             Reviewed;         231 AA.
AC   Q8IV03; Q5VZX7; Q8N923; Q8NCG2;
DE   RecName: Full=Leucine rich adaptor protein 1-like;
GN   Name=LURAP1L; Synonyms=C9orf150; ORFNames=HYST0841;
//
ID   LURA1_HUMAN             Reviewed;         239 AA.
AC   Q96LR2;
DE   RecName: Full=Leucine rich adaptor protein 1;
DE   AltName: Full=Leucine repeat adapter protein 35A;
GN   Name=LURAP1; Synonyms=C1orf190, LRAP35A, LRP35A;
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
//
ID   LUZP1_HUMAN             Reviewed;        1076 AA.
AC   Q86V48; Q5TH93; Q8N4X3; Q8TEH1;
DE   RecName: Full=Leucine zipper protein 1;
GN   Name=LUZP1;
DR   GO; GO:0060840; P:artery development; IEA:Ensembl.
DR   GO; GO:0021503; P:neural fold bending; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   LUZP2_HUMAN             Reviewed;         346 AA.
AC   Q86TE4; A2RUB8; E9PN53; Q6UXE7; Q6ZS65;
DE   RecName: Full=Leucine zipper protein 2;
DE   Flags: Precursor;
GN   Name=LUZP2; ORFNames=UNQ2566/PRO6246;
//
ID   LUZP4_HUMAN             Reviewed;         313 AA.
AC   Q9P127; B3KSD6;
DE   RecName: Full=Leucine zipper protein 4;
DE   AltName: Full=Cancer/testis antigen 28;
DE            Short=CT-28;
DE            Short=CT28;
DE   AltName: Full=Tumor antigen HOM-TES-85;
GN   Name=LUZP4;
//
ID   LUZP6_HUMAN             Reviewed;          58 AA.
AC   Q538Z0; K7EQW5;
DE   RecName: Full=Leucine zipper protein 6;
DE   AltName: Full=Myeloproliferative disease-associated 6 kDa antigen;
GN   Name=LUZP6; Synonyms=MPD6;
//
ID   LV001_HUMAN             Reviewed;         117 AA.
AC   P04211;
DE   RecName: Full=Ig lambda chain V region 4A;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV105_HUMAN             Reviewed;         103 AA.
AC   P01703;
DE   RecName: Full=Ig lambda chain V-I region NEWM;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV101_HUMAN             Reviewed;         111 AA.
AC   P01699;
DE   RecName: Full=Ig lambda chain V-I region VOR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV107_HUMAN             Reviewed;         130 AA.
AC   P06316;
DE   RecName: Full=Ig lambda chain V-I region BL2;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV106_HUMAN             Reviewed;         109 AA.
AC   P04208;
DE   RecName: Full=Ig lambda chain V-I region WAH;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV103_HUMAN             Reviewed;         111 AA.
AC   P01701;
DE   RecName: Full=Ig lambda chain V-I region NEW;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV109_HUMAN             Reviewed;         109 AA.
AC   P06888;
DE   RecName: Full=Ig lambda chain V-I region EPS;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV102_HUMAN             Reviewed;         112 AA.
AC   P01700;
DE   RecName: Full=Ig lambda chain V-I region HA;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV108_HUMAN             Reviewed;         112 AA.
AC   P06887;
DE   RecName: Full=Ig lambda chain V-I region MEM;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV104_HUMAN             Reviewed;         111 AA.
AC   P01702;
DE   RecName: Full=Ig lambda chain V-I region NIG-64;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV201_HUMAN             Reviewed;         111 AA.
AC   P01704;
DE   RecName: Full=Ig lambda chain V-II region TOG;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV203_HUMAN             Reviewed;         111 AA.
AC   P01706;
DE   RecName: Full=Ig lambda chain V-II region BOH;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV205_HUMAN             Reviewed;         109 AA.
AC   P01708;
DE   RecName: Full=Ig lambda chain V-II region BUR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV204_HUMAN             Reviewed;         111 AA.
AC   P01707;
DE   RecName: Full=Ig lambda chain V-II region TRO;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV209_HUMAN             Reviewed;         111 AA.
AC   P01712;
DE   RecName: Full=Ig lambda chain V-II region WIN;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV208_HUMAN             Reviewed;         111 AA.
AC   P01711;
DE   RecName: Full=Ig lambda chain V-II region VIL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV202_HUMAN             Reviewed;         111 AA.
AC   P01705;
DE   RecName: Full=Ig lambda chain V-II region NEI;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV206_HUMAN             Reviewed;         111 AA.
AC   P01709;
DE   RecName: Full=Ig lambda chain V-II region MGC;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV211_HUMAN             Reviewed;         112 AA.
AC   P04209;
DE   RecName: Full=Ig lambda chain V-II region NIG-84;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV207_HUMAN             Reviewed;         111 AA.
AC   P01710;
DE   RecName: Full=Ig lambda chain V-II region BO;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV302_HUMAN             Reviewed;         111 AA.
AC   P80748;
DE   RecName: Full=Ig lambda chain V-III region LOI;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV210_HUMAN             Reviewed;         110 AA.
AC   P01713;
DE   RecName: Full=Ig lambda chain V-II region NIG-58;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV301_HUMAN             Reviewed;         108 AA.
AC   P01714;
DE   RecName: Full=Ig lambda chain V-III region SH;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV402_HUMAN             Reviewed;         106 AA.
AC   P01716;
DE   RecName: Full=Ig lambda chain V-IV region X;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV403_HUMAN             Reviewed;         107 AA.
AC   P01717;
DE   RecName: Full=Ig lambda chain V-IV region Hil;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV501_HUMAN             Reviewed;         108 AA.
AC   P01719;
DE   RecName: Full=Ig lambda chain V-V region DEL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV212_HUMAN             Reviewed;         111 AA.
AC   P80422;
DE   RecName: Full=Ig gamma lambda chain V-II region DOT;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   LV602_HUMAN             Reviewed;         112 AA.
AC   P01722;
DE   RecName: Full=Ig lambda chain V-VI region NIG-48;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV404_HUMAN             Reviewed;         106 AA.
AC   P01718;
DE   RecName: Full=Ig lambda chain V-IV region Kern;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV603_HUMAN             Reviewed;         111 AA.
AC   P06317;
DE   RecName: Full=Ig lambda chain V-VI region SUT;
DR   GO; GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV604_HUMAN             Reviewed;         111 AA.
AC   P06318;
DE   RecName: Full=Ig lambda chain V-VI region WLT;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV401_HUMAN             Reviewed;         106 AA.
AC   P01715;
DE   RecName: Full=Ig lambda chain V-IV region Bau;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV601_HUMAN             Reviewed;         112 AA.
AC   P01721;
DE   RecName: Full=Ig lambda chain V-VI region AR;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV605_HUMAN             Reviewed;         131 AA.
AC   P06319;
DE   RecName: Full=Ig lambda chain V-VI region EB4;
DE   Flags: Precursor;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV701_HUMAN             Reviewed;         111 AA.
AC   P01720;
DE   RecName: Full=Ig lambda chain V-VII region MOT;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LV405_HUMAN             Reviewed;         106 AA.
AC   P06889;
DE   RecName: Full=Ig lambda chain V-IV region MOL;
DR   GO; GO:0003823; F:antigen binding; NAS:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   LX12B_HUMAN             Reviewed;         701 AA.
AC   O75342;
DE   RecName: Full=Arachidonate 12-lipoxygenase, 12R-type;
DE            Short=12R-LOX;
DE            Short=12R-lipoxygenase;
DE            EC=1.13.11.-;
DE   AltName: Full=Epidermis-type lipoxygenase 12;
GN   Name=ALOX12B;
DR   GO; GO:0004052; F:arachidonate 12-lipoxygenase activity; IMP:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:1990136; F:linoleate 9S-lipoxygenase activity; ISS:UniProtKB.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IMP:UniProtKB.
DR   GO; GO:0046513; P:ceramide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0061436; P:establishment of skin barrier; ISS:UniProtKB.
DR   GO; GO:0051122; P:hepoxilin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0019372; P:lipoxygenase pathway; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0070257; P:positive regulation of mucus secretion; IMP:UniProtKB.
DR   GO; GO:0006497; P:protein lipidation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IDA:UniProtKB.
//
ID   LX15B_HUMAN             Reviewed;         676 AA.
AC   O15296; D3DTR2; Q8IYQ2; Q8TEV3; Q8TEV4; Q8TEV5; Q8TEV6; Q9UKM4;
DE   RecName: Full=Arachidonate 15-lipoxygenase B;
DE            Short=15-LOX-B;
DE            EC=1.13.11.33;
DE   AltName: Full=15-lipoxygenase 2;
DE            Short=15-LOX-2;
DE   AltName: Full=Arachidonate 15-lipoxygenase type II;
DE   AltName: Full=Linoleate 13-lipoxygenase 15-LOb;
DE            EC=1.13.11.-;
GN   Name=ALOX15B;
DR   GO; GO:0050473; F:arachidonate 15-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0036403; F:arachidonate 8(S)-lipoxygenase activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0016165; F:linoleate 13S-lipoxygenase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0051122; P:hepoxilin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0043651; P:linoleic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:UniProtKB.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; IDA:UniProtKB.
DR   GO; GO:0090197; P:positive regulation of chemokine secretion; IMP:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:UniProtKB.
DR   GO; GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030850; P:prostate gland development; NAS:UniProtKB.
DR   GO; GO:0030856; P:regulation of epithelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LXN_HUMAN               Reviewed;         222 AA.
AC   Q9BS40; Q96PN2; Q9NQS6;
DE   RecName: Full=Latexin;
DE   AltName: Full=Endogenous carboxypeptidase inhibitor;
DE            Short=ECI;
DE   AltName: Full=Protein MUM;
DE   AltName: Full=Tissue carboxypeptidase inhibitor;
DE            Short=TCI;
GN   Name=LXN;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
//
ID   LY65B_HUMAN             Reviewed;         201 AA.
AC   Q8NDX9; B0UXB2; B0UZ65; B0UZP8; B7ZCA3; Q5SQ62; Q5SST3; Q9UKT0;
AC   Q9UMQ0;
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G5b;
DE   Flags: Precursor;
GN   Name=LY6G5B; Synonyms=C6orf19, G5B;
//
ID   LY65C_HUMAN             Reviewed;         150 AA.
AC   Q5SRR4; A6NCW4; B0UXB3; B0UXB4; B0UZ69; B0UZQ0; B1B0L9; O95871;
AC   Q5SQ59; Q8NDY0; Q8NDY1;
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G5c;
DE   Flags: Precursor;
GN   Name=LY6G5C; Synonyms=C6orf20, G5C, NG33;
//
ID   LY66D_HUMAN             Reviewed;         133 AA.
AC   O95868; A2BEY8; B0UXC1; B0V019; B0V1Y6; Q4VX50;
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G6d;
DE            Short=Protein Ly6-D;
DE   AltName: Full=Megakaryocyte-enhanced gene transcript 1 protein;
DE   Flags: Precursor;
GN   Name=LY6G6D; Synonyms=C6orf23, G6D, MEGT1, NG25;
//
ID   LY66C_HUMAN             Reviewed;         125 AA.
AC   O95867; Q5SRS8; Q8IY94;
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G6c;
DE   Flags: Precursor;
GN   Name=LY6G6C; Synonyms=C6orf24, G6C, NG24; ORFNames=UNQ1947/PRO4430;
//
ID   LY66F_HUMAN             Reviewed;         297 AA.
AC   Q5SQ64; B0UXB7; O95869; Q7Z5H2; Q96QC7;
DE   RecName: Full=Lymphocyte antigen 6 complex locus protein G6f;
DE   Flags: Precursor;
GN   Name=LY6G6F; Synonyms=C6orf21, G6F, LY6G6D, NG32;
//
ID   LY6D_HUMAN              Reviewed;         128 AA.
AC   Q14210; B2R5F1; D3DWJ0; O43783; Q6GTV9; Q8TBD4; Q92933;
DE   RecName: Full=Lymphocyte antigen 6D;
DE            Short=Ly-6D;
DE   AltName: Full=E48 antigen;
DE   Flags: Precursor;
GN   Name=LY6D; Synonyms=E48;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0030098; P:lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
//
ID   LY6E_HUMAN              Reviewed;         131 AA.
AC   Q16553; B2R4X5; D3DWJ2; Q0VDE5;
DE   RecName: Full=Lymphocyte antigen 6E;
DE            Short=Ly-6E;
DE   AltName: Full=Retinoic acid-induced gene E protein;
DE            Short=RIG-E;
DE   AltName: Full=Stem cell antigen 2;
DE            Short=SCA-2;
DE   AltName: Full=Thymic shared antigen 1;
DE            Short=TSA-1;
DE   Flags: Precursor;
GN   Name=LY6E; Synonyms=9804, RIGE, SCA2, TSA1;
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048242; P:epinephrine secretion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042415; P:norepinephrine metabolic process; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
//
ID   LY6K_HUMAN              Reviewed;         165 AA.
AC   Q17RY6; G3V116; O15227; Q9BVD7;
DE   RecName: Full=Lymphocyte antigen 6K;
DE            Short=Ly-6K;
DE   Flags: Precursor;
GN   Name=LY6K; Synonyms=CO16;
//
ID   LY6H_HUMAN              Reviewed;         140 AA.
AC   O94772; B2RAD2; J3KQI0; Q6IAX0;
DE   RecName: Full=Lymphocyte antigen 6H;
DE            Short=Ly-6H;
DE   Flags: Precursor;
GN   Name=LY6H;
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
//
ID   LY75_HUMAN              Reviewed;        1722 AA.
AC   O60449; O75913; Q53R46; Q53TF5; Q7Z575; Q7Z577;
DE   RecName: Full=Lymphocyte antigen 75;
DE            Short=Ly-75;
DE   AltName: Full=C-type lectin domain family 13 member B;
DE   AltName: Full=DEC-205;
DE   AltName: Full=gp200-MR6;
DE   AltName: CD_antigen=CD205;
DE   Flags: Precursor;
GN   Name=LY75; Synonyms=CD205, CLEC13B;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
//
ID   LY86_HUMAN              Reviewed;         162 AA.
AC   O95711; Q9UQC4;
DE   RecName: Full=Lymphocyte antigen 86;
DE            Short=Ly-86;
DE   AltName: Full=Protein MD-1;
DE   Flags: Precursor;
GN   Name=LY86; Synonyms=MD1;
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IGI:MGI.
//
ID   LY96_HUMAN              Reviewed;         160 AA.
AC   Q9Y6Y9; B3Y6A5;
DE   RecName: Full=Lymphocyte antigen 96;
DE            Short=Ly-96;
DE   AltName: Full=ESOP-1;
DE   AltName: Full=Protein MD-2;
DE   Flags: Precursor;
GN   Name=LY96; Synonyms=ESOP1, MD2;
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0001875; F:lipopolysaccharide receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0032497; P:detection of lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:MGI.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   LY9_HUMAN               Reviewed;         655 AA.
AC   Q9HBG7; A8K7N3; Q14775; Q5VYI3; Q6P2J4; Q9H4N5; Q9NQ24;
DE   RecName: Full=T-lymphocyte surface antigen Ly-9;
DE   AltName: Full=Cell surface molecule Ly-9;
DE   AltName: Full=Lymphocyte antigen 9;
DE   AltName: Full=SLAM family member 3;
DE            Short=SLAMF3;
DE   AltName: Full=Signaling lymphocytic activation molecule 3;
DE   AltName: CD_antigen=CD229;
DE   Flags: Precursor;
GN   Name=LY9; ORFNames=CDABP0070;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   LYAG_HUMAN              Reviewed;         952 AA.
AC   P10253; Q09GN4; Q14351; Q16302; Q8IWE7;
DE   RecName: Full=Lysosomal alpha-glucosidase;
DE            EC=3.2.1.20;
DE   AltName: Full=Acid maltase;
DE   AltName: Full=Aglucosidase alfa;
DE   Contains:
DE     RecName: Full=76 kDa lysosomal alpha-glucosidase;
DE   Contains:
DE     RecName: Full=70 kDa lysosomal alpha-glucosidase;
DE   Flags: Precursor;
GN   Name=GAA;
DR   GO; GO:0004558; F:alpha-glucosidase activity; IDA:BHF-UCL.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0032450; F:maltose alpha-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0002086; P:diaphragm contraction; IMP:BHF-UCL.
DR   GO; GO:0006006; P:glucose metabolic process; IC:BHF-UCL.
DR   GO; GO:0005980; P:glycogen catabolic process; IDA:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IMP:BHF-UCL.
DR   GO; GO:0000023; P:maltose metabolic process; IC:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IMP:BHF-UCL.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0005985; P:sucrose metabolic process; IC:BHF-UCL.
DR   GO; GO:0043587; P:tongue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0043181; P:vacuolar sequestering; IMP:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   LYAM1_HUMAN             Reviewed;         372 AA.
AC   P14151; B2R6Q8; P15023; Q9UJ43;
DE   RecName: Full=L-selectin;
DE   AltName: Full=CD62 antigen-like family member L;
DE   AltName: Full=Leukocyte adhesion molecule 1;
DE            Short=LAM-1;
DE   AltName: Full=Leukocyte surface antigen Leu-8;
DE   AltName: Full=Leukocyte-endothelial cell adhesion molecule 1;
DE            Short=LECAM1;
DE   AltName: Full=Lymph node homing receptor;
DE   AltName: Full=TQ1;
DE   AltName: Full=gp90-MEL;
DE   AltName: CD_antigen=CD62L;
DE   Flags: Precursor;
GN   Name=SELL; Synonyms=LNHR, LYAM1;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0043208; F:glycosphingolipid binding; TAS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; TAS:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
//
ID   LYAM2_HUMAN             Reviewed;         610 AA.
AC   P16581; A2RRD6; P16111;
DE   RecName: Full=E-selectin;
DE   AltName: Full=CD62 antigen-like family member E;
DE   AltName: Full=Endothelial leukocyte adhesion molecule 1;
DE            Short=ELAM-1;
DE   AltName: Full=Leukocyte-endothelial cell adhesion molecule 2;
DE            Short=LECAM2;
DE   AltName: CD_antigen=CD62E;
DE   Flags: Precursor;
GN   Name=SELE; Synonyms=ELAM1;
DR   GO; GO:0070492; F:oligosaccharide binding; IDA:BHF-UCL.
DR   GO; GO:0043274; F:phospholipase binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033691; F:sialic acid binding; IDA:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IMP:BHF-UCL.
DR   GO; GO:0030029; P:actin filament-based process; IDA:BHF-UCL.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IMP:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019722; P:calcium-mediated signaling; TAS:BHF-UCL.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0002523; P:leukocyte migration involved in inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IMP:BHF-UCL.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IDA:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; TAS:BHF-UCL.
DR   GO; GO:0034612; P:response to tumor necrosis factor; TAS:BHF-UCL.
//
ID   LYAM3_HUMAN             Reviewed;         830 AA.
AC   P16109; Q5R344; Q8IVD1;
DE   RecName: Full=P-selectin;
DE   AltName: Full=CD62 antigen-like family member P;
DE   AltName: Full=Granule membrane protein 140;
DE            Short=GMP-140;
DE   AltName: Full=Leukocyte-endothelial cell adhesion molecule 3;
DE            Short=LECAM3;
DE   AltName: Full=Platelet activation dependent granule-external membrane protein;
DE            Short=PADGEM;
DE   AltName: CD_antigen=CD62P;
DE   Flags: Precursor;
GN   Name=SELP; Synonyms=GMRP, GRMP;
DR   GO; GO:0042806; F:fucose binding; IDA:BHF-UCL.
DR   GO; GO:0043208; F:glycosphingolipid binding; TAS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IMP:BHF-UCL.
DR   GO; GO:0070492; F:oligosaccharide binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033691; F:sialic acid binding; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.
DR   GO; GO:0033623; P:regulation of integrin activation; IMP:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IC:BHF-UCL.
//
ID   LYAR_HUMAN              Reviewed;         379 AA.
AC   Q9NX58; D3DVS4; Q6FI78; Q9NYS1;
DE   RecName: Full=Cell growth-regulating nucleolar protein;
GN   Name=LYAR; ORFNames=PNAS-5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
//
ID   LYG2_HUMAN              Reviewed;         212 AA.
AC   Q86SG7; Q53RW0;
DE   RecName: Full=Lysozyme g-like protein 2;
DE            EC=3.2.1.-;
DE   Flags: Precursor;
GN   Name=LYG2; Synonyms=LYGH;
DR   GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
//
ID   LYG1_HUMAN              Reviewed;         194 AA.
AC   Q8N1E2; Q53RV9;
DE   RecName: Full=Lysozyme g-like protein 1;
DE            EC=3.2.1.-;
DE   Flags: Precursor;
GN   Name=LYG1; ORFNames=UNQ1939/PRO4422;
DR   GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
//
ID   LYL1_HUMAN              Reviewed;         280 AA.
AC   P12980; O76102;
DE   RecName: Full=Protein lyl-1;
DE   AltName: Full=Class A basic helix-loop-helix protein 18;
DE            Short=bHLHa18;
DE   AltName: Full=Lymphoblastic leukemia-derived sequence 1;
GN   Name=LYL1; Synonyms=BHLHA18;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001955; P:blood vessel maturation; IMP:UniProtKB.
DR   GO; GO:0060216; P:definitive hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   LYNX1_HUMAN             Reviewed;         131 AA.
AC   Q9BZG9; D3DWI7; G3XAC2; Q86SR0;
DE   RecName: Full=Ly-6/neurotoxin-like protein 1;
DE   AltName: Full=Secreted Ly-6/uPAR domain-containing protein 2;
DE   AltName: Full=Secreted Ly-6/uPAR-related protein 2;
DE            Short=SLURP-2;
DE   Flags: Precursor;
GN   Name=LYNX1; Synonyms=SLURP2;
//
ID   LYOX_HUMAN              Reviewed;         417 AA.
AC   P28300; B2R5Q3; Q5FWF0;
DE   RecName: Full=Protein-lysine 6-oxidase;
DE            EC=1.4.3.13;
DE   AltName: Full=Lysyl oxidase;
DE   Flags: Precursor;
GN   Name=LOX;
DR   GO; GO:0005507; F:copper ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004720; F:protein-lysine 6-oxidase activity; TAS:ProtInc.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0048251; P:elastic fiber assembly; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   LYN_HUMAN               Reviewed;         512 AA.
AC   P07948; A0AVQ5;
DE   RecName: Full=Tyrosine-protein kinase Lyn;
DE            EC=2.7.10.2;
DE   AltName: Full=Lck/Yes-related novel protein tyrosine kinase;
DE   AltName: Full=V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;
DE   AltName: Full=p53Lyn;
DE   AltName: Full=p56Lyn;
GN   Name=LYN; Synonyms=JTK8;
DR   GuidetoPHARMACOLOGY; 2060; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0043208; F:glycosphingolipid binding; IEA:Ensembl.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0001782; P:B cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0050663; P:cytokine secretion; IEA:Ensembl.
DR   GO; GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.
DR   GO; GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0002553; P:histamine secretion by mast cell; IEA:Ensembl.
DR   GO; GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IC:UniProtKB.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.
DR   GO; GO:1902532; P:negative regulation of intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.
DR   GO; GO:0002762; P:negative regulation of myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IDA:UniProtKB.
DR   GO; GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0060369; P:positive regulation of Fc receptor mediated stimulatory signaling pathway; IEA:Ensembl.
DR   GO; GO:0060252; P:positive regulation of glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0070668; P:positive regulation of mast cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0070447; P:positive regulation of oligodendrocyte progenitor proliferation; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0070304; P:positive regulation of stress-activated protein kinase signaling cascade; IDA:UniProtKB.
DR   GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0002902; P:regulation of B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.
DR   GO; GO:0001817; P:regulation of cytokine production; ISS:UniProtKB.
DR   GO; GO:0050707; P:regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0033003; P:regulation of mast cell activation; ISS:UniProtKB.
DR   GO; GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.
DR   GO; GO:0090025; P:regulation of monocyte chemotaxis; IMP:UniProtKB.
DR   GO; GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; TAS:UniProtKB.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; ISS:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006991; P:response to sterol depletion; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; TAS:GOC.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   LYPA1_HUMAN             Reviewed;         230 AA.
AC   O75608; O43202; Q9UQF9;
DE   RecName: Full=Acyl-protein thioesterase 1;
DE            Short=APT-1;
DE            Short=hAPT1;
DE            EC=3.1.2.-;
DE   AltName: Full=Lysophospholipase 1;
DE   AltName: Full=Lysophospholipase I;
DE            Short=LPL-I;
DE            Short=LysoPLA I;
GN   Name=LYPLA1; Synonyms=APT1, LPL1;
DR   GO; GO:0004622; F:lysophospholipase activity; TAS:ProtInc.
DR   GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IMP:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0002084; P:protein depalmitoylation; IEA:Ensembl.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LYPD1_HUMAN             Reviewed;         141 AA.
AC   Q8N2G4; H7BXW6; Q6ZP52; Q6ZWI4; Q96AC2;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 1;
DE   AltName: Full=Putative HeLa tumor suppressor;
DE            Short=PHTS;
DE   Flags: Precursor;
GN   Name=LYPD1; Synonyms=LYPDC1; ORFNames=PSEC0181, UNQ3079/PRO9917;
//
ID   LYPA2_HUMAN             Reviewed;         231 AA.
AC   O95372; Q7Z4Z2;
DE   RecName: Full=Acyl-protein thioesterase 2;
DE            Short=APT-2;
DE            EC=3.1.2.-;
DE   AltName: Full=Lysophospholipase II;
DE            Short=LPL-II;
DE            Short=LysoPLA II;
GN   Name=LYPLA2; Synonyms=APT2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   LYPD2_HUMAN             Reviewed;         125 AA.
AC   Q6UXB3; A8K2R6; Q0VD64; Q0VF31;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=LYPD2; Synonyms=LYPDC2; ORFNames=UNQ430/PRO788;
//
ID   LYPD3_HUMAN             Reviewed;         346 AA.
AC   O95274; Q9UJ74;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 3;
DE   AltName: Full=GPI-anchored metastasis-associated protein C4.4A homolog;
DE   AltName: Full=Matrigel-induced gene C4 protein;
DE            Short=MIG-C4;
DE   Flags: Precursor;
GN   Name=LYPD3; Synonyms=C4.4A; ORFNames=UNQ491/PRO1007;
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
//
ID   LYPD4_HUMAN             Reviewed;         246 AA.
AC   Q6UWN0; Q8IYW0;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=LYPD4; ORFNames=UNQ2552/PRO6181;
//
ID   LYPD5_HUMAN             Reviewed;         251 AA.
AC   Q6UWN5; Q6PEX9; Q96DR2;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 5;
DE   Flags: Precursor;
GN   Name=LYPD5; ORFNames=UNQ1908/PRO4356;
//
ID   LYPD6_HUMAN             Reviewed;         171 AA.
AC   Q86Y78; B3KWC0; Q4G121; Q53TR3; Q659B1;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 6;
DE   Flags: Precursor;
GN   Name=LYPD6; ORFNames=UNQ3023/PRO9821;
//
ID   LYPD8_HUMAN             Reviewed;         237 AA.
AC   Q6UX82;
DE   RecName: Full=Ly6/PLAUR domain-containing protein 8;
DE   Flags: Precursor;
GN   Name=LYPD8; ORFNames=UNQ511/PRO1026;
//
ID   LYPL1_HUMAN             Reviewed;         237 AA.
AC   Q5VWZ2; A8K677; Q5VWZ3; Q7Z4A3; Q96AV0;
DE   RecName: Full=Lysophospholipase-like protein 1;
DE            EC=3.1.2.-;
GN   Name=LYPLAL1;
DR   GO; GO:0004622; F:lysophospholipase activity; NAS:UniProtKB.
DR   GO; GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0002084; P:protein depalmitoylation; IEA:Ensembl.
//
ID   LYRIC_HUMAN             Reviewed;         582 AA.
AC   Q86UE4; Q05DH2; Q52QU9; Q6PK07; Q8TCX3;
DE   RecName: Full=Protein LYRIC;
DE   AltName: Full=3D3/LYRIC;
DE   AltName: Full=Astrocyte elevated gene-1 protein;
DE            Short=AEG-1;
DE   AltName: Full=Lysine-rich CEACAM1 co-isolated protein;
DE   AltName: Full=Metadherin;
DE   AltName: Full=Metastasis adhesion protein;
GN   Name=MTDH; Synonyms=AEG1, LYRIC;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; IEA:Ensembl.
//
ID   LYRM1_HUMAN             Reviewed;         122 AA.
AC   O43325; B2R4M5;
DE   RecName: Full=LYR motif-containing protein 1;
GN   Name=LYRM1;
//
ID   LYRM2_HUMAN             Reviewed;          88 AA.
AC   Q9NU23; B2R4U2; E1P517;
DE   RecName: Full=LYR motif-containing protein 2;
GN   Name=LYRM2;
//
ID   LYRM4_HUMAN             Reviewed;          91 AA.
AC   Q9HD34; A8K543; Q5XKP1;
DE   RecName: Full=LYR motif-containing protein 4;
GN   Name=LYRM4; Synonyms=C6orf149, ISD11; ORFNames=CGI-203;
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   LYRM5_HUMAN             Reviewed;          90 AA.
AC   Q6IPR1; J3KPI7;
DE   RecName: Full=LYR motif-containing protein 5;
GN   Name=LYRM5;
//
ID   LYRM7_HUMAN             Reviewed;         104 AA.
AC   Q5U5X0; A8MPQ9; Q86Y68;
DE   RecName: Full=Complex III assembly factor LYRM7;
DE   AltName: Full=LYR motif-containing protein 7;
GN   Name=LYRM7; Synonyms=C5orf31, MZM1L;
//
ID   LYRM9_HUMAN             Reviewed;          78 AA.
AC   A8MSI8; A6NJT7; Q6X7B8;
DE   RecName: Full=LYR motif-containing protein 9;
GN   Name=LYRM9; Synonyms=C17orf108; ORFNames=HSD24;
//
ID   LYSC_HUMAN              Reviewed;         148 AA.
AC   P61626; P00695; Q13170; Q9UCF8;
DE   RecName: Full=Lysozyme C;
DE            EC=3.2.1.17;
DE   AltName: Full=1,4-beta-N-acetylmuramidase C;
DE   Flags: Precursor;
GN   Name=LYZ; Synonyms=LZM;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0003796; F:lysozyme activity; TAS:UniProtKB.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   LYSM1_HUMAN             Reviewed;         227 AA.
AC   Q96S90; B4DQA1; Q69YX9;
DE   RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 1;
GN   Name=LYSMD1; ORFNames=SB145;
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYSM2_HUMAN             Reviewed;         215 AA.
AC   Q8IV50; Q5CZ88; Q8WTV3;
DE   RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 2;
GN   Name=LYSMD2;
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYSM3_HUMAN             Reviewed;         306 AA.
AC   Q7Z3D4; Q5H9U0; Q6PEK0; Q9NTE9;
DE   RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 3;
GN   Name=LYSMD3;
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYSM4_HUMAN             Reviewed;         296 AA.
AC   Q5XG99; A6NII6; A8K2N1; Q96LY7;
DE   RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 4;
GN   Name=LYSMD4;
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYST_HUMAN              Reviewed;        3801 AA.
AC   Q99698; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99709; Q9H133;
DE   RecName: Full=Lysosomal-trafficking regulator;
DE   AltName: Full=Beige homolog;
GN   Name=LYST; Synonyms=CHS, CHS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0032510; P:endosome to lysosome transport via multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0030595; P:leukocyte chemotaxis; ISS:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0033364; P:mast cell secretory granule organization; ISS:UniProtKB.
DR   GO; GO:0032438; P:melanosome organization; ISS:UniProtKB.
DR   GO; GO:0007017; P:microtubule-based process; IEA:Ensembl.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:UniProtKB.
DR   GO; GO:0002446; P:neutrophil mediated immunity; IEA:Ensembl.
DR   GO; GO:0055091; P:phospholipid homeostasis; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IMP:UniProtKB.
DR   GO; GO:0032816; P:positive regulation of natural killer cell activation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0033299; P:secretion of lysosomal enzymes; IEA:Ensembl.
DR   GO; GO:0002456; P:T cell mediated immunity; IEA:Ensembl.
//
ID   LYVE1_HUMAN             Reviewed;         322 AA.
AC   Q9Y5Y7; Q8TC18; Q9UNF4;
DE   RecName: Full=Lymphatic vessel endothelial hyaluronic acid receptor 1;
DE            Short=LYVE-1;
DE   AltName: Full=Cell surface retention sequence-binding protein 1;
DE            Short=CRSBP-1;
DE   AltName: Full=Extracellular link domain-containing protein 1;
DE   AltName: Full=Hyaluronic acid receptor;
DE   Flags: Precursor;
GN   Name=LYVE1; Synonyms=CRSBP1, HAR, XLKD1; ORFNames=UNQ230/PRO263;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:Ensembl.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   LYZL1_HUMAN             Reviewed;         148 AA.
AC   Q6UWQ5; Q5T921; Q8WW16;
DE   RecName: Full=Lysozyme-like protein 1;
DE            EC=3.2.1.17;
DE   Flags: Precursor;
GN   Name=LYZL1; Synonyms=LYC2; ORFNames=UNQ648/PRO1278;
DR   GO; GO:0003796; F:lysozyme activity; IEA:UniProtKB-EC.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYZL2_HUMAN             Reviewed;         148 AA.
AC   Q7Z4W2; Q6NZ69;
DE   RecName: Full=Lysozyme-like protein 2;
DE            Short=Lysozyme-2;
DE            EC=3.2.1.17;
DE   Flags: Precursor;
GN   Name=LYZL2;
DR   GO; GO:0003796; F:lysozyme activity; IEA:UniProtKB-EC.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYZL5_HUMAN             Reviewed;         159 AA.
AC   Q96QH8; Q6UWD1;
DE   RecName: Full=Sperm acrosome-associated protein 5;
DE            EC=3.2.1.17;
DE   AltName: Full=Lysozyme-like protein 5;
DE   AltName: Full=Sperm-specific lysozyme-like protein X;
DE            Short=SLLP-X;
DE   Flags: Precursor;
GN   Name=SPACA5; Synonyms=LYZL5, SPACA5A; ORFNames=UNQ6288/PRO20753;
GN   and
GN   Name=SPACA5B;
DR   GO; GO:0003796; F:lysozyme activity; IEA:UniProtKB-EC.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYZL4_HUMAN             Reviewed;         146 AA.
AC   Q96KX0;
DE   RecName: Full=Lysozyme-like protein 4;
DE            Short=Lysozyme-4;
DE   Flags: Precursor;
GN   Name=LYZL4; Synonyms=LYC4;
DR   GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LYZL6_HUMAN             Reviewed;         148 AA.
AC   O75951; Q6UW30;
DE   RecName: Full=Lysozyme-like protein 6;
DE            EC=3.2.1.17;
DE   Flags: Precursor;
GN   Name=LYZL6; Synonyms=LYC1; ORFNames=UNQ754/PRO1485;
DR   GO; GO:0003796; F:lysozyme activity; IEA:UniProtKB-EC.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
//
ID   LZIC_HUMAN              Reviewed;         190 AA.
AC   Q8WZA0; B2R6F0; Q96IU1;
DE   RecName: Full=Protein LZIC;
DE   AltName: Full=Leucine zipper and CTNNBIP1 domain-containing protein;
DE   AltName: Full=Leucine zipper and ICAT homologous domain-containing protein;
GN   Name=LZIC;
DR   GO; GO:0007417; P:central nervous system development; IBA:RefGenome.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
//
ID   LZTL1_HUMAN             Reviewed;         299 AA.
AC   Q9NQ48; B3KSI9; B4E0K7; Q8TC61; Q9NQ56;
DE   RecName: Full=Leucine zipper transcription factor-like protein 1;
GN   Name=LZTFL1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0072594; P:establishment of protein localization to organelle; IEA:Ensembl.
//
ID   LZTR1_HUMAN             Reviewed;         840 AA.
AC   Q8N653; Q14776; Q20WK0;
DE   RecName: Full=Leucine-zipper-like transcriptional regulator 1;
DE            Short=LZTR-1;
GN   Name=LZTR1; Synonyms=TCFL2;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
//
ID   LZTS1_HUMAN             Reviewed;         596 AA.
AC   Q9Y250; D3DSQ6; Q9Y5V7; Q9Y5V8; Q9Y5V9; Q9Y5W0; Q9Y5W1; Q9Y5W2;
DE   RecName: Full=Leucine zipper putative tumor suppressor 1;
DE   AltName: Full=F37/esophageal cancer-related gene-coding leucine-zipper motif;
DE   AltName: Full=Fez1;
GN   Name=LZTS1; Synonyms=FEZ1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0016242; P:negative regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   LZTS2_HUMAN             Reviewed;         669 AA.
AC   Q9BRK4; B1AL14; D3DR72; Q8N3I0; Q96J79; Q96JL2;
DE   RecName: Full=Leucine zipper putative tumor suppressor 2;
DE            Short=hLZTS2;
DE   AltName: Full=Protein LAPSER1;
GN   Name=LZTS2; Synonyms=KIAA1813, LAPSER1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000910; P:cytokinesis; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051013; P:microtubule severing; IEA:UniProtKB-HAMAP.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051168; P:nuclear export; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051255; P:spindle midzone assembly; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   LZTS3_HUMAN             Reviewed;         673 AA.
AC   O60299; A2A2Q7; D3DVX6; Q8IXX8;
DE   RecName: Full=Leucine zipper putative tumor suppressor 3;
DE   AltName: Full=ProSAP-interacting protein 1;
DE            Short=ProSAPiP1;
GN   Name=LZTS3; Synonyms=KIAA0552, PROSAPIP1;
//
ID   M10L1_HUMAN             Reviewed;        1211 AA.
AC   Q9BXT6; A7E211; A8MXC6; B7WPP1; B7Z7R1; F5H403; Q5TGD5; Q8NBD4;
AC   Q9NXW3; Q9UFB3; Q9UGX9;
DE   RecName: Full=Putative helicase Mov10l1;
DE            EC=3.6.4.13;
DE   AltName: Full=Moloney leukemia virus 10-like protein 1;
DE            Short=MOV10-like protein 1;
GN   Name=MOV10L1;
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; NAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; TAS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0007281; P:germ cell development; IEP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
//
ID   M17L2_HUMAN             Reviewed;         206 AA.
AC   Q567V2; Q96P34; Q96QA0; Q9BSG4;
DE   RecName: Full=Mpv17-like protein 2;
GN   Name=MPV17L2; Synonyms=FKSG24;
//
ID   M18BP_HUMAN             Reviewed;        1132 AA.
AC   Q6P0N0; D3DSA7; Q86V14; Q96PY4; Q9NUR5; Q9Y4X9;
DE   RecName: Full=Mis18-binding protein 1;
DE   AltName: Full=Kinetochore-associated protein KNL-2 homolog;
DE            Short=HsKNL-2;
DE   AltName: Full=P243;
GN   Name=MIS18BP1; Synonyms=C14orf106, KIAA1903, KNL2, M18BP1;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   M1AP_HUMAN              Reviewed;         530 AA.
AC   Q8TC57; Q6ZP30; Q96L07;
DE   RecName: Full=Meiosis 1 arrest protein;
DE   AltName: Full=Meiosis 1-arresting protein;
DE   AltName: Full=Meiosis 1-associated protein;
DE   AltName: Full=Spermatogenesis-associated protein 37;
GN   Name=M1AP; Synonyms=C2orf65, SPATA37;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0031497; P:chromatin assembly; NAS:UniProtKB.
DR   GO; GO:0007292; P:female gamete generation; ISS:UniProtKB.
DR   GO; GO:0051308; P:male meiosis chromosome separation; ISS:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   M1BL1_HUMAN             Reviewed;          61 AA.
AC   P0DM35;
DE   RecName: Full=Metallothionein 1H-like protein 1;
GN   Name=MT1HL1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   M1IP1_HUMAN             Reviewed;         183 AA.
AC   Q9NPA3; D3DWB2;
DE   RecName: Full=Mid1-interacting protein 1;
DE   AltName: Full=Gastrulation-specific G12-like protein;
DE   AltName: Full=Mid1-interacting G12-like protein;
DE   AltName: Full=Protein STRAIT11499;
DE   AltName: Full=Spot 14-related protein;
DE            Short=S14R;
DE            Short=Spot 14-R;
GN   Name=MID1IP1; Synonyms=MIG12;
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; ISS:UniProtKB.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051351; P:positive regulation of ligase activity; ISS:UniProtKB.
DR   GO; GO:0051258; P:protein polymerization; ISS:UniProtKB.
DR   GO; GO:0046890; P:regulation of lipid biosynthetic process; ISS:UniProtKB.
//
ID   M21D2_HUMAN             Reviewed;         491 AA.
AC   Q8IYB1; Q86VD8;
DE   RecName: Full=Protein MB21D2;
DE   AltName: Full=Mab-21 domain-containing protein 2;
GN   Name=MB21D2; Synonyms=C3orf59;
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
//
ID   M2GD_HUMAN              Reviewed;         866 AA.
AC   Q9UI17; B2RBN0;
DE   RecName: Full=Dimethylglycine dehydrogenase, mitochondrial;
DE            EC=1.5.8.4;
DE   AltName: Full=ME2GLYDH;
DE   Flags: Precursor;
GN   Name=DMGDH;
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:InterPro.
DR   GO; GO:0047865; F:dimethylglycine dehydrogenase activity; IMP:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006579; P:amino-acid betaine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019695; P:choline metabolic process; NAS:UniProtKB.
DR   GO; GO:0006546; P:glycine catabolic process; IEA:InterPro.
DR   GO; GO:0006544; P:glycine metabolic process; IMP:UniProtKB.
//
ID   M2OM_HUMAN              Reviewed;         314 AA.
AC   Q02978; F5GY65; O75537; Q969P7;
DE   RecName: Full=Mitochondrial 2-oxoglutarate/malate carrier protein;
DE            Short=OGCP;
DE   AltName: Full=Solute carrier family 25 member 11;
GN   Name=SLC25A11; Synonyms=SLC20A4;
DR   GO; GO:0015367; F:oxoglutarate:malate antiporter activity; TAS:Reactome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0015742; P:alpha-ketoglutarate transport; TAS:GOC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   M3K10_HUMAN             Reviewed;         954 AA.
AC   Q02779; Q12761; Q14871;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 10;
DE            EC=2.7.11.25;
DE   AltName: Full=Mixed lineage kinase 2;
DE   AltName: Full=Protein kinase MST;
GN   Name=MAP3K10; Synonyms=MLK2, MST;
DR   GuidetoPHARMACOLOGY; 2070; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0007256; P:activation of JNKK activity; ISS:GOC.
DR   GO; GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB.
//
ID   M3K11_HUMAN             Reviewed;         847 AA.
AC   Q16584; Q53H00; Q59F06; Q6P2G4;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 11;
DE            EC=2.7.11.25;
DE   AltName: Full=Mixed lineage kinase 3;
DE   AltName: Full=Src-homology 3 domain-containing proline-rich kinase;
GN   Name=MAP3K11; Synonyms=MLK3, PTK1, SPRK;
DR   GuidetoPHARMACOLOGY; 2071; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IMP:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0007017; P:microtubule-based process; IMP:UniProtKB.
DR   GO; GO:0000080; P:mitotic G1 phase; IMP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   M3K12_HUMAN             Reviewed;         859 AA.
AC   Q12852; B3KSS9; G3V1Y2; Q86VQ5; Q8WY25;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 12;
DE            EC=2.7.11.25;
DE   AltName: Full=Dual leucine zipper bearing kinase;
DE            Short=DLK;
DE   AltName: Full=Leucine-zipper protein kinase;
DE            Short=ZPK;
DE   AltName: Full=MAPK-upstream kinase;
DE            Short=MUK;
DE   AltName: Full=Mixed lineage kinase;
GN   Name=MAP3K12; Synonyms=ZPK;
DR   GuidetoPHARMACOLOGY; 2072; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0016572; P:histone phosphorylation; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   M3K13_HUMAN             Reviewed;         966 AA.
AC   O43283; B2R6U2; B4DLE3; B4DMV2; B4DZJ4; D3DNU1; Q05BY6; Q15450;
AC   Q2NKN3;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 13;
DE            EC=2.7.11.25;
DE   AltName: Full=Leucine zipper-bearing kinase;
DE   AltName: Full=Mixed lineage kinase;
DE            Short=MLK;
GN   Name=MAP3K13; Synonyms=LZK;
DR   GuidetoPHARMACOLOGY; 2073; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   M3K14_HUMAN             Reviewed;         947 AA.
AC   Q99558; A8K2D8; D3DX67; Q8IYN1;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 14;
DE            EC=2.7.11.25;
DE   AltName: Full=NF-kappa-beta-inducing kinase;
DE            Short=HsNIK;
DE   AltName: Full=Serine/threonine-protein kinase NIK;
GN   Name=MAP3K14; Synonyms=NIK;
DR   GuidetoPHARMACOLOGY; 2074; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004704; F:NF-kappaB-inducing kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; ISS:UniProtKB.
DR   GO; GO:0038061; P:NIK/NF-kappaB signaling; ISS:GOC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   M3K15_HUMAN             Reviewed;        1313 AA.
AC   Q6ZN16; A2AI49; A2AI50; A6NJ61; Q5JPR4; Q6ZMV3;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 15;
DE            EC=2.7.11.25;
DE   AltName: Full=Apoptosis signal-regulating kinase 3;
DE   AltName: Full=MAPK/ERK kinase kinase 15;
DE            Short=MEK kinase 15;
DE            Short=MEKK 15;
GN   Name=MAP3K15; Synonyms=ASK3;
DR   GuidetoPHARMACOLOGY; 2075; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000186; P:activation of MAPKK activity; IBA:GOC.
DR   GO; GO:0000165; P:MAPK cascade; IBA:GOC.
//
ID   M3K19_HUMAN             Reviewed;        1328 AA.
AC   Q56UN5; B2RP57; Q56UN1; Q56UN2; Q56UN3; Q56UN4; Q8N4E9; Q9H5T2;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 19;
DE            EC=2.7.11.1;
DE   AltName: Full=Regulated in COPD, protein kinase;
DE   AltName: Full=SPS1/STE20-related protein kinase YSK4;
GN   Name=MAP3K19; Synonyms=RCK, YSK4;
DR   GuidetoPHARMACOLOGY; 2076; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0000186; P:activation of MAPKK activity; IBA:GOC.
DR   GO; GO:0000165; P:MAPK cascade; IBA:GOC.
//
ID   M3K1_HUMAN              Reviewed;        1512 AA.
AC   Q13233;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 1;
DE            EC=2.7.11.25;
DE   AltName: Full=MAPK/ERK kinase kinase 1;
DE            Short=MEK kinase 1;
DE            Short=MEKK 1;
GN   Name=MAP3K1; Synonyms=MAPKKK1, MEKK, MEKK1;
DR   GuidetoPHARMACOLOGY; 2069; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008545; F:JUN kinase kinase activity; IEA:Ensembl.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0000186; P:activation of MAPKK activity; NAS:GOC.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   M3K2_HUMAN              Reviewed;         619 AA.
AC   Q9Y2U5; B9EG87; Q53QL9; Q53S75; Q59GZ6; Q8NC32; Q9NYK3;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 2;
DE            EC=2.7.11.25;
DE   AltName: Full=MAPK/ERK kinase kinase 2;
DE            Short=MEK kinase 2;
DE            Short=MEKK 2;
GN   Name=MAP3K2; Synonyms=MAPKKK2, MEKK2;
DR   GuidetoPHARMACOLOGY; 2077; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   M3K3_HUMAN              Reviewed;         626 AA.
AC   Q99759; B2RCW2; D3DU15; Q5BKZ6; Q8N3I9;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 3;
DE            EC=2.7.11.25;
DE   AltName: Full=MAPK/ERK kinase kinase 3;
DE            Short=MEK kinase 3;
DE            Short=MEKK 3;
GN   Name=MAP3K3; Synonyms=MAPKKK3, MEKK3;
DR   GuidetoPHARMACOLOGY; 2078; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0000165; P:MAPK cascade; TAS:ProtInc.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:MGI.
//
ID   M3K4_HUMAN              Reviewed;        1608 AA.
AC   Q9Y6R4; A6H8W0; B7ZLD3; B9EG75; Q5VTT8; Q5VTT9; Q92612; Q9H408;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 4;
DE            EC=2.7.11.25;
DE   AltName: Full=MAP three kinase 1;
DE   AltName: Full=MAPK/ERK kinase kinase 4;
DE            Short=MEK kinase 4;
DE            Short=MEKK 4;
GN   Name=MAP3K4; Synonyms=KIAA0213, MAPKKK4, MEKK4, MTK1;
DR   GuidetoPHARMACOLOGY; 2079; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:UniProtKB.
DR   GO; GO:0060718; P:chorionic trophoblast cell differentiation; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0019100; P:male germ-line sex determination; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IDA:GOC.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010225; P:response to UV-C; IMP:UniProtKB.
//
ID   M3K6_HUMAN              Reviewed;        1288 AA.
AC   O95382; A2ACE8; A2VDG4; A2VDG5; Q59HF4; Q5SSD4; Q75PK3; Q96B75;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 6;
DE            EC=2.7.11.25;
DE   AltName: Full=Apoptosis signal-regulating kinase 2;
GN   Name=MAP3K6; Synonyms=ASK2, MAPKKK6, MEKK6;
DR   GuidetoPHARMACOLOGY; 2081; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   M3K5_HUMAN              Reviewed;        1374 AA.
AC   Q99683; Q5THN3; Q99461;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 5;
DE            EC=2.7.11.25;
DE   AltName: Full=Apoptosis signal-regulating kinase 1;
DE            Short=ASK-1;
DE   AltName: Full=MAPK/ERK kinase kinase 5;
DE            Short=MEK kinase 5;
DE            Short=MEKK 5;
GN   Name=MAP3K5; Synonyms=ASK1, MAPKKK5, MEKK5;
DR   GuidetoPHARMACOLOGY; 2080; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:GOC.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; IDA:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   M3K7_HUMAN              Reviewed;         606 AA.
AC   O43318; B2RE27; E1P523; O43317; O43319; Q5TDN2; Q5TDN3; Q5TDT7;
AC   Q9NTR3; Q9NZ70;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 7;
DE            EC=2.7.11.25;
DE   AltName: Full=Transforming growth factor-beta-activated kinase 1;
DE            Short=TGF-beta-activated kinase 1;
GN   Name=MAP3K7; Synonyms=TAK1;
DR   GuidetoPHARMACOLOGY; 2082; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IEA:Ensembl.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; EXP:Reactome.
DR   GO; GO:0097110; F:scaffold protein binding; IDA:MGI.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; IDA:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   M3K8_HUMAN              Reviewed;         467 AA.
AC   P41279; A8K2Q5; D3DRX1; Q14275; Q5T855; Q9HC81;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 8;
DE            EC=2.7.11.25;
DE   AltName: Full=Cancer Osaka thyroid oncogene;
DE   AltName: Full=Proto-oncogene c-Cot;
DE   AltName: Full=Serine/threonine-protein kinase cot;
DE   AltName: Full=Tumor progression locus 2;
DE            Short=TPL-2;
GN   Name=MAP3K8; Synonyms=COT, ESTF;
DR   GuidetoPHARMACOLOGY; 2083; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0000186; P:activation of MAPKK activity; IBA:GOC.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000165; P:MAPK cascade; IBA:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   M3K9_HUMAN              Reviewed;        1104 AA.
AC   P80192; A3KN85; Q0D2G7; Q6EH31; Q9H2N5;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase 9;
DE            EC=2.7.11.25;
DE   AltName: Full=Mixed lineage kinase 1;
GN   Name=MAP3K9; Synonyms=MLK1, PRKE1;
DR   GuidetoPHARMACOLOGY; 2084; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.
DR   GO; GO:0004708; F:MAP kinase kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0007256; P:activation of JNKK activity; ISS:GOC.
DR   GO; GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   M3KCL_HUMAN             Reviewed;         242 AA.
AC   P57077; D3DSE0; Q8TCL9;
DE   RecName: Full=MAP3K7 C-terminal-like protein;
DE   AltName: Full=TAK1-like protein;
GN   Name=MAP3K7CL; Synonyms=C21orf7, TAK1L;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   M3KL4_HUMAN             Reviewed;        1036 AA.
AC   Q5TCX8; B2RN34; Q5TCX7; Q5TCX9; Q8WWN1; Q8WWN2; Q96JM1;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase MLK4;
DE            EC=2.7.11.25;
DE   AltName: Full=Mixed lineage kinase 4;
GN   Name=MLK4; Synonyms=KIAA1804;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
//
ID   M4A10_HUMAN             Reviewed;         267 AA.
AC   Q96PG2; B2RP45; Q96PG3;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 10;
DE   AltName: Full=CD20 antigen-like 7;
GN   Name=MS4A10; Synonyms=CD20L7, MS4A9;
//
ID   M4A12_HUMAN             Reviewed;         267 AA.
AC   Q9NXJ0; F5GX98; Q8N6L4;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 12;
GN   Name=MS4A12;
//
ID   M4A13_HUMAN             Reviewed;         152 AA.
AC   Q5J8X5; B2RTS9; Q5J8X3; Q5J8X4;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 13;
DE   AltName: Full=Testis-expressed transmembrane protein 4;
GN   Name=MS4A13;
//
ID   M4A15_HUMAN             Reviewed;         240 AA.
AC   Q8N5U1; A9UJY6; A9UJY7; F2Z2J5;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 15;
GN   Name=MS4A15;
//
ID   M4A4A_HUMAN             Reviewed;         239 AA.
AC   Q96JQ5; Q8TEZ6; Q96PG7; Q9BY18; Q9H3V3; Q9P1S3;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 4A;
DE   AltName: Full=CD20 antigen-like 1;
DE   AltName: Full=Four-span transmembrane protein 1;
GN   Name=MS4A4A; Synonyms=4SPAN1, CD20L1, MS4A4; ORFNames=HDCME31P;
//
ID   M4A14_HUMAN             Reviewed;         679 AA.
AC   Q96JA4; Q2TVT5; Q3B7W3; Q86XH8; Q9NTC2;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 14;
DE   AltName: Full=Testis development protein NYD-SP21;
GN   Name=MS4A14; Synonyms=MS4A13, MS4A16;
//
ID   M4A18_HUMAN             Reviewed;         323 AA.
AC   Q3C1V0;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 18;
GN   Name=MS4A18;
//
ID   M4A4E_HUMAN             Reviewed;         132 AA.
AC   Q96PG1; Q3C1W1; Q3C1W3; Q3C1W4;
DE   RecName: Full=Putative membrane-spanning 4-domains subfamily A member 4E;
GN   Name=MS4A4E;
//
ID   M4A6A_HUMAN             Reviewed;         248 AA.
AC   Q9H2W1; A8K755; Q7Z4E8; Q8TBV7; Q8TEZ4; Q8TEZ5; Q96PG6; Q9H2L1;
AC   Q9H2N3; Q9H3V1; Q9HC76;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 6A;
DE   AltName: Full=CD20 antigen-like 3;
DE   AltName: Full=Four-span transmembrane protein 3;
GN   Name=MS4A6A; Synonyms=4SPAN3, CD20L3, MS4A6; ORFNames=CDA01, MSTP090;
//
ID   M4A8_HUMAN              Reviewed;         250 AA.
AC   Q9BY19; Q8TCA5;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 8;
DE   AltName: Full=Four-span transmembrane protein 4;
DE   AltName: Full=Membrane-spanning 4-domains subfamily A member 8B;
GN   Name=MS4A8; Synonyms=4SPAN4, MS4A8B;
//
ID   M4A6E_HUMAN             Reviewed;         147 AA.
AC   Q96DS6; Q3MIL2; Q8NE56; Q96PG4; Q96PG5;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 6E;
GN   Name=MS4A6E;
//
ID   M4K1_HUMAN              Reviewed;         833 AA.
AC   Q92918;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Hematopoietic progenitor kinase;
DE   AltName: Full=MAPK/ERK kinase kinase kinase 1;
DE            Short=MEK kinase kinase 1;
DE            Short=MEKKK 1;
GN   Name=MAP4K1; Synonyms=HPK1;
DR   GuidetoPHARMACOLOGY; 2085; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IC:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
//
ID   M4K2_HUMAN              Reviewed;         820 AA.
AC   Q12851; Q86VU3;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=B lymphocyte serine/threonine-protein kinase;
DE   AltName: Full=Germinal center kinase;
DE            Short=GC kinase;
DE   AltName: Full=MAPK/ERK kinase kinase kinase 2;
DE            Short=MEK kinase kinase 2;
DE            Short=MEKKK 2;
DE   AltName: Full=Rab8-interacting protein;
GN   Name=MAP4K2; Synonyms=GCK, RAB8IP;
DR   GuidetoPHARMACOLOGY; 2086; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008349; F:MAP kinase kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IBA:GOC.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006903; P:vesicle targeting; IEA:Ensembl.
//
ID   M4K3_HUMAN              Reviewed;         894 AA.
AC   Q8IVH8; Q6IQ39; Q8IVH7; Q9UDM5; Q9Y6R5;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Germinal center kinase-related protein kinase;
DE            Short=GLK;
DE   AltName: Full=MAPK/ERK kinase kinase kinase 3;
DE            Short=MEK kinase kinase 3;
DE            Short=MEKKK 3;
GN   Name=MAP4K3; Synonyms=RAB8IPL1;
DR   GuidetoPHARMACOLOGY; 2087; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008349; F:MAP kinase kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IBA:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
//
ID   M4K4_HUMAN              Reviewed;        1239 AA.
AC   O95819; O75172; Q9NST7;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 4;
DE            EC=2.7.11.1;
DE   AltName: Full=HPK/GCK-like kinase HGK;
DE   AltName: Full=MAPK/ERK kinase kinase kinase 4;
DE            Short=MEK kinase kinase 4;
DE            Short=MEKKK 4;
DE   AltName: Full=Nck-interacting kinase;
GN   Name=MAP4K4; Synonyms=HGK, KIAA0687, NIK;
DR   GuidetoPHARMACOLOGY; 2088; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   M4K5_HUMAN              Reviewed;         846 AA.
AC   Q9Y4K4; Q8IYF6;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 5;
DE            EC=2.7.11.1;
DE   AltName: Full=Kinase homologous to SPS1/STE20;
DE            Short=KHS;
DE   AltName: Full=MAPK/ERK kinase kinase kinase 5;
DE            Short=MEK kinase kinase 5;
DE            Short=MEKKK 5;
GN   Name=MAP4K5;
DR   GuidetoPHARMACOLOGY; 2089; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   MA13P_HUMAN             Reviewed;         341 AA.
AC   A6NCF6;
DE   RecName: Full=Putative MAGE domain-containing protein MAGEA13P;
GN   Name=MAGEA13P;
//
ID   MA1A1_HUMAN             Reviewed;         653 AA.
AC   P33908; Q9NU44; Q9UJI3;
DE   RecName: Full=Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA;
DE            EC=3.2.1.113;
DE   AltName: Full=Man(9)-alpha-mannosidase;
DE            Short=Man9-mannosidase;
DE   AltName: Full=Mannosidase alpha class 1A member 1;
DE   AltName: Full=Processing alpha-1,2-mannosidase IA;
DE            Short=Alpha-1,2-mannosidase IA;
GN   Name=MAN1A1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0015923; F:mannosidase activity; TAS:ProtInc.
DR   GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MA1A2_HUMAN             Reviewed;         641 AA.
AC   O60476; Q9H510;
DE   RecName: Full=Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB;
DE            EC=3.2.1.113;
DE   AltName: Full=Mannosidase alpha class 1A member 2;
DE   AltName: Full=Processing alpha-1,2-mannosidase IB;
DE            Short=Alpha-1,2-mannosidase IB;
GN   Name=MAN1A2; Synonyms=MAN1B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0006491; P:N-glycan processing; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
//
ID   MA1B1_HUMAN             Reviewed;         699 AA.
AC   Q9UKM7; Q5VSG3; Q9BRS9; Q9Y5K7;
DE   RecName: Full=Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase;
DE            EC=3.2.1.113;
DE   AltName: Full=ER alpha-1,2-mannosidase;
DE   AltName: Full=ER mannosidase 1;
DE            Short=ERMan1;
DE   AltName: Full=Man9GlcNAc2-specific-processing alpha-mannosidase;
DE   AltName: Full=Mannosidase alpha class 1B member 1;
GN   Name=MAN1B1; ORFNames=UNQ747/PRO1477;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; NAS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MA1C1_HUMAN             Reviewed;         630 AA.
AC   Q9NR34; A6NNE2; B2RNP2; Q9Y545;
DE   RecName: Full=Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC;
DE            EC=3.2.1.113;
DE   AltName: Full=HMIC;
DE   AltName: Full=Mannosidase alpha class 1C member 1;
DE   AltName: Full=Processing alpha-1,2-mannosidase IC;
DE            Short=Alpha-1,2-mannosidase IC;
GN   Name=MAN1C1; Synonyms=MAN1A3, MAN1C;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0004571; F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; TAS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MA2A1_HUMAN             Reviewed;        1144 AA.
AC   Q16706; Q16767;
DE   RecName: Full=Alpha-mannosidase 2;
DE            EC=3.2.1.114;
DE   AltName: Full=Golgi alpha-mannosidase II;
DE            Short=AMan II;
DE            Short=Man II;
DE   AltName: Full=Mannosidase alpha class 2A member 1;
DE   AltName: Full=Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase;
GN   Name=MAN2A1; Synonyms=MANA2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016799; F:hydrolase activity, hydrolyzing N-glycosyl compounds; IEA:Ensembl.
DR   GO; GO:0004572; F:mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0006491; P:N-glycan processing; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007033; P:vacuole organization; IEA:Ensembl.
//
ID   MA2A2_HUMAN             Reviewed;        1150 AA.
AC   P49641; A6NH12; A8K1E8; Q13754;
DE   RecName: Full=Alpha-mannosidase 2x;
DE            EC=3.2.1.114;
DE   AltName: Full=Alpha-mannosidase IIx;
DE            Short=Man IIx;
DE   AltName: Full=Mannosidase alpha class 2A member 2;
DE   AltName: Full=Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase;
GN   Name=MAN2A2; Synonyms=MANA2X;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016799; F:hydrolase activity, hydrolyzing N-glycosyl compounds; IEA:Ensembl.
DR   GO; GO:0004572; F:mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MA2B1_HUMAN             Reviewed;        1011 AA.
AC   O00754; G5E928; O15330; Q16680; Q93094; Q9BW13;
DE   RecName: Full=Lysosomal alpha-mannosidase;
DE            Short=Laman;
DE            EC=3.2.1.24;
DE   AltName: Full=Lysosomal acid alpha-mannosidase;
DE   AltName: Full=Mannosidase alpha class 2B member 1;
DE   AltName: Full=Mannosidase alpha-B;
DE   Contains:
DE     RecName: Full=Lysosomal alpha-mannosidase A peptide;
DE   Contains:
DE     RecName: Full=Lysosomal alpha-mannosidase B peptide;
DE   Contains:
DE     RecName: Full=Lysosomal alpha-mannosidase C peptide;
DE   Contains:
DE     RecName: Full=Lysosomal alpha-mannosidase D peptide;
DE   Contains:
DE     RecName: Full=Lysosomal alpha-mannosidase E peptide;
DE   Flags: Precursor;
GN   Name=MAN2B1; Synonyms=LAMAN, MANB;
DR   GO; GO:0004559; F:alpha-mannosidase activity; TAS:ProtInc.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:UniProtKB.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   GO; GO:0006517; P:protein deglycosylation; TAS:ProtInc.
//
ID   MA2B2_HUMAN             Reviewed;        1009 AA.
AC   Q9Y2E5; Q66MP2; Q86T67;
DE   RecName: Full=Epididymis-specific alpha-mannosidase;
DE            EC=3.2.1.24;
DE   AltName: Full=Mannosidase alpha class 2B member 2;
DE   Flags: Precursor;
GN   Name=MAN2B2; Synonyms=KIAA0935;
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:Ensembl.
//
ID   MA2C1_HUMAN             Reviewed;        1040 AA.
AC   Q9NTJ4; H3BMX2; H3BQY8; H3BUT6; Q13358; Q68EM8; Q9UL64;
DE   RecName: Full=Alpha-mannosidase 2C1;
DE            EC=3.2.1.24;
DE   AltName: Full=Alpha mannosidase 6A8B;
DE   AltName: Full=Alpha-D-mannoside mannohydrolase;
DE   AltName: Full=Mannosidase alpha class 2C member 1;
GN   Name=MAN2C1; Synonyms=MANA, MANA1;
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
//
ID   MA6D1_HUMAN             Reviewed;         199 AA.
AC   Q9H9H5;
DE   RecName: Full=MAP6 domain-containing protein 1;
DE   AltName: Full=21 kDa STOP-like protein;
DE            Short=SL21;
GN   Name=MAP6D1;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0018009; P:N-terminal peptidyl-L-cysteine N-palmitoylation; IEA:Ensembl.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:Ensembl.
//
ID   MA7D2_HUMAN             Reviewed;         732 AA.
AC   Q96T17; B7Z2J8; B7Z3S7; B9EGC7; C9JMA4; C9JYW0; Q5EBN1; Q5JPS7;
AC   Q6PIC7; Q8N792;
DE   RecName: Full=MAP7 domain-containing protein 2;
GN   Name=MAP7D2;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   MA7D1_HUMAN             Reviewed;         841 AA.
AC   Q3KQU3; D3DPS4; Q7L8J5; Q8N905; Q8TAK0; Q9HBQ2; Q9NW29; Q9ULN3;
DE   RecName: Full=MAP7 domain-containing protein 1;
DE   AltName: Full=Arginine/proline-rich coiled-coil domain-containing protein 1;
DE   AltName: Full=Proline/arginine-rich coiled-coil domain-containing protein 1;
GN   Name=MAP7D1; Synonyms=KIAA1187, PARCC1, RPRC1; ORFNames=PP2464;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   MA7D3_HUMAN             Reviewed;         876 AA.
AC   Q8IWC1; A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; Q5JXI5; Q5JXI6;
AC   Q6P2S1; Q9H9M8;
DE   RecName: Full=MAP7 domain-containing protein 3;
GN   Name=MAP7D3;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   MAAI_HUMAN              Reviewed;         216 AA.
AC   O43708; A6NED0; A6NNB8; A8MWD7; B2RCK3; O15308; O75430; Q6IB17;
AC   Q7Z610; Q9BV63;
DE   RecName: Full=Maleylacetoacetate isomerase;
DE            Short=MAAI;
DE            EC=5.2.1.2;
DE   AltName: Full=GSTZ1-1;
DE   AltName: Full=Glutathione S-transferase zeta 1;
DE            EC=2.5.1.18;
GN   Name=GSTZ1; Synonyms=MAAI;
DR   GO; GO:0004602; F:glutathione peroxidase activity; TAS:ProtInc.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0016034; F:maleylacetoacetate isomerase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IDA:UniProtKB.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006572; P:tyrosine catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   MAAT1_HUMAN             Reviewed;         603 AA.
AC   Q7Z4T9; A0AVK2; A8K1J9; B3KP23; B4DG52; B4DZ14; C9JUG4; Q68DX2;
AC   Q8TD41; Q96A45; Q96JE8;
DE   RecName: Full=Protein MAATS1;
DE   AltName: Full=AMY-1-associating protein expressed in testis 1;
DE            Short=AAT-1;
DE   AltName: Full=MYCBP/AMY-1-associated testis-expressed protein 1;
GN   Name=MAATS1; Synonyms=AAT1, C3orf15;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAAS1_HUMAN             Reviewed;         139 AA.
AC   Q8N8E1;
DE   RecName: Full=Putative uncharacterized protein encoded by MAPKAPK5-AS1;
DE   AltName: Full=MAPKAPK5 antisense RNA 1;
DE   AltName: Full=MAPKAPK5 antisense gene protein 1;
GN   Name=MAPKAPK5-AS1; Synonyms=C12orf47;
//
ID   MABP1_HUMAN             Reviewed;        1514 AA.
AC   O60336; A6NM93; A8K8P9; Q14CB5; Q14CD8; Q49AJ8; Q5W9G9;
DE   RecName: Full=Mitogen-activated protein kinase-binding protein 1;
DE   AltName: Full=JNK-binding protein 1;
DE            Short=JNKBP-1;
GN   Name=MAPKBP1; Synonyms=JNKBP1, KIAA0596;
//
ID   MACC1_HUMAN             Reviewed;         852 AA.
AC   Q6ZN28; A8MUS5; B2RNR9; Q6ZQN8; Q7Z5A5;
DE   RecName: Full=Metastasis-associated in colon cancer protein 1;
DE   AltName: Full=SH3 domain-containing protein 7a5;
GN   Name=MACC1;
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MACD2_HUMAN             Reviewed;         448 AA.
AC   A1Z1Q3; A6NFF7; B0QZ39; B3KWV0; Q0P6D5; Q495E0; Q5W199; Q6ZN71;
DE   RecName: Full=O-acetyl-ADP-ribose deacetylase MACROD2;
DE            EC=3.2.2.-;
DE            EC=3.5.1.-;
DE   AltName: Full=MACRO domain-containing protein 2;
DE   AltName: Full=[Protein ADP-ribosylglutamate] hydrolase;
GN   Name=MACROD2; Synonyms=C20orf133;
DR   GO; GO:0019213; F:deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0051725; P:protein de-ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0042278; P:purine nucleoside metabolic process; IDA:UniProtKB.
//
ID   MACF1_HUMAN             Reviewed;        7388 AA.
AC   Q9UPN3; B1ALC5; E9PJT0; O75053; Q5VW20; Q8WXY1; Q8WXY2; Q96PK2;
AC   Q9H540; Q9UKP0; Q9ULG9;
DE   RecName: Full=Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5;
DE   AltName: Full=620 kDa actin-binding protein;
DE            Short=ABP620;
DE   AltName: Full=Actin cross-linking family protein 7;
DE   AltName: Full=Macrophin-1;
DE   AltName: Full=Trabeculin-alpha;
GN   Name=MACF1; Synonyms=ABP620, ACF7, KIAA0465, KIAA1251;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; NAS:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006620; P:posttranslational protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
//
ID   MACD1_HUMAN             Reviewed;         325 AA.
AC   Q9BQ69; Q9UH96;
DE   RecName: Full=O-acetyl-ADP-ribose deacetylase MACROD1;
DE            EC=3.2.2.-;
DE            EC=3.5.1.-;
DE   AltName: Full=MACRO domain-containing protein 1;
DE   AltName: Full=Protein LRP16;
DE   AltName: Full=[Protein ADP-ribosylglutamate] hydrolase;
GN   Name=MACROD1; Synonyms=LRP16;
DR   GO; GO:0019213; F:deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0051725; P:protein de-ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0042278; P:purine nucleoside metabolic process; IDA:UniProtKB.
//
ID   MACOI_HUMAN             Reviewed;         664 AA.
AC   Q8N5G2; B1AK00; Q2TLX5; Q2TLX6; Q9NVG6;
DE   RecName: Full=Macoilin;
DE   AltName: Full=Transmembrane protein 57;
GN   Name=TMEM57;
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
//
ID   MAD1_HUMAN              Reviewed;         221 AA.
AC   Q05195; B2R6V8; B7ZLI6; D6W5G2; Q6FI41;
DE   RecName: Full=Max dimerization protein 1;
DE            Short=Max dimerizer 1;
DE   AltName: Full=Protein MAD;
GN   Name=MXD1; Synonyms=MAD;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAD3_HUMAN              Reviewed;         206 AA.
AC   Q9BW11; Q53HK1; Q7Z4Y0; Q8NDJ7; Q96ME3;
DE   RecName: Full=Max dimerization protein 3;
DE            Short=Max dimerizer 3;
DE   AltName: Full=Class C basic helix-loop-helix protein 13;
DE            Short=bHLHc13;
DE   AltName: Full=Max-associated protein 3;
DE   AltName: Full=Max-interacting transcriptional repressor MAD3;
DE   AltName: Full=Myx;
GN   Name=MXD3; Synonyms=BHLHC13, MAD3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MADCA_HUMAN             Reviewed;         382 AA.
AC   Q13477; A5PKV4; B2RPL9; O60222; O75867; Q5UGI7;
DE   RecName: Full=Mucosal addressin cell adhesion molecule 1;
DE            Short=MAdCAM-1;
DE            Short=hMAdCAM-1;
DE   Flags: Precursor;
GN   Name=MADCAM1;
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MAD4_HUMAN              Reviewed;         209 AA.
AC   Q14582; A2A335; Q5TZX4;
DE   RecName: Full=Max dimerization protein 4;
DE            Short=Max dimerizer 4;
DE   AltName: Full=Class C basic helix-loop-helix protein 12;
DE            Short=bHLHc12;
DE   AltName: Full=Max-associated protein 4;
DE   AltName: Full=Max-interacting transcriptional repressor MAD4;
GN   Name=MXD4; Synonyms=BHLHC12, MAD4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MADD_HUMAN              Reviewed;        1647 AA.
AC   Q8WXG6; A8K8S7; B5MEE5; D3DQR4; O15065; O15293; Q15732; Q15741;
AC   Q8IWD7; Q8WXG3; Q8WXG4; Q8WXG5; Q8WZ63;
DE   RecName: Full=MAP kinase-activating death domain protein;
DE   AltName: Full=Differentially expressed in normal and neoplastic cells;
DE   AltName: Full=Insulinoma glucagonoma clone 20;
DE   AltName: Full=Rab3 GDP/GTP exchange factor;
GN   Name=MADD; Synonyms=DENN, IG20, KIAA0358;
DR   GO; GO:0005123; F:death receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; TAS:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IMP:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:2001236; P:regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:1902041; P:regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0032483; P:regulation of Rab protein signal transduction; IDA:FlyBase.
//
ID   MADL2_HUMAN             Reviewed;         307 AA.
AC   A6NDP7;
DE   RecName: Full=Myeloid-associated differentiation marker-like protein 2;
GN   Name=MYADML2;
//
ID   MAEA_HUMAN              Reviewed;         396 AA.
AC   Q7L5Y9; O95285; Q5JB54; Q6ZRD6; Q9BQ11; Q9H9V6; Q9H9Z4; Q9NW84;
DE   RecName: Full=Macrophage erythroblast attacher;
DE   AltName: Full=Cell proliferation-inducing gene 5 protein;
DE   AltName: Full=Erythroblast macrophage protein;
DE   AltName: Full=Human lung cancer oncogene 10 protein;
DE            Short=HLC-10;
GN   Name=MAEA; Synonyms=EMP; ORFNames=HLC10, PIG5;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0048822; P:enucleate erythrocyte development; IEA:Ensembl.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW.
DR   GO; GO:0033033; P:negative regulation of myeloid cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; NAS:UniProtKB.
//
ID   MAEL_HUMAN              Reviewed;         434 AA.
AC   Q96JY0; B4DY43; E9JVC3; Q49AP9; Q5VZP8; Q9UIW6;
DE   RecName: Full=Protein maelstrom homolog;
GN   Name=MAEL;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0046620; P:regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   MAF1_HUMAN              Reviewed;         256 AA.
AC   Q9H063; D3DWL4;
DE   RecName: Full=Repressor of RNA polymerase III transcription MAF1 homolog;
GN   Name=MAF1;
DR   GO; GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0016480; P:negative regulation of transcription from RNA polymerase III promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAFA_HUMAN              Reviewed;         353 AA.
AC   Q8NHW3;
DE   RecName: Full=Transcription factor MafA;
DE   AltName: Full=Pancreatic beta-cell-specific transcriptional activator;
DE   AltName: Full=Transcription factor RIPE3b1;
DE   AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog A;
GN   Name=MAFA;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0030073; P:insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0009749; P:response to glucose; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAFB_HUMAN              Reviewed;         323 AA.
AC   Q9Y5Q3; B3KNE1; Q9H1F1;
DE   RecName: Full=Transcription factor MafB;
DE            Short=Maf-B;
DE   AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog B;
GN   Name=MAFB; Synonyms=KRML;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0035284; P:brain segmentation; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0021571; P:rhombomere 5 development; IEA:Ensembl.
DR   GO; GO:0021572; P:rhombomere 6 development; IEA:Ensembl.
DR   GO; GO:0007379; P:segment specification; IEA:Ensembl.
DR   GO; GO:0007423; P:sensory organ development; TAS:ProtInc.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAFF_HUMAN              Reviewed;         164 AA.
AC   Q9ULX9; B4DV49; Q9Y525;
DE   RecName: Full=Transcription factor MafF;
DE   AltName: Full=U-Maf;
DE   AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog F;
GN   Name=MAFF;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007567; P:parturition; TAS:ProtInc.
DR   GO; GO:0045604; P:regulation of epidermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MAFG_HUMAN              Reviewed;         162 AA.
AC   O15525;
DE   RecName: Full=Transcription factor MafG;
DE   AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog G;
DE   AltName: Full=hMAF;
GN   Name=MAFG;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030641; P:regulation of cellular pH; IEA:Ensembl.
DR   GO; GO:0045604; P:regulation of epidermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAFIP_HUMAN             Reviewed;         124 AA.
AC   Q8WZ33;
DE   RecName: Full=MaFF-interacting protein;
DE   AltName: Full=Tektin-4 like protein PP5644;
GN   Name=MAFIP; Synonyms=MIP; ORFNames=PP5644;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAFK_HUMAN              Reviewed;         156 AA.
AC   O60675; A4D214;
DE   RecName: Full=Transcription factor MafK;
DE   AltName: Full=Erythroid transcription factor NF-E2 p18 subunit;
GN   Name=MAFK;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAF_HUMAN               Reviewed;         373 AA.
AC   O75444; Q66I47; Q9UP93;
DE   RecName: Full=Transcription factor Maf;
DE   AltName: Full=Proto-oncogene c-Maf;
DE   AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog;
GN   Name=MAF;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MAGA3_HUMAN             Reviewed;         314 AA.
AC   P43357; Q6FHI6;
DE   RecName: Full=Melanoma-associated antigen 3;
DE   AltName: Full=Antigen MZ2-D;
DE   AltName: Full=Cancer/testis antigen 1.3;
DE            Short=CT1.3;
DE   AltName: Full=MAGE-3 antigen;
GN   Name=MAGEA3; Synonyms=MAGE3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGA2_HUMAN             Reviewed;         314 AA.
AC   P43356; A8K328; Q32NC6;
DE   RecName: Full=Melanoma-associated antigen 2;
DE   AltName: Full=Cancer/testis antigen 1.2;
DE            Short=CT1.2;
DE   AltName: Full=MAGE-2 antigen;
GN   Name=MAGEA2; Synonyms=MAGE2, MAGEA2A;
GN   and
GN   Name=MAGEA2B; Synonyms=MAGE2, MAGEA2;
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0090398; P:cellular senescence; IDA:UniProtKB.
DR   GO; GO:1901984; P:negative regulation of protein acetylation; IDA:UniProtKB.
DR   GO; GO:0033234; P:negative regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0072331; P:signal transduction by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAGA4_HUMAN             Reviewed;         317 AA.
AC   P43358; Q14798;
DE   RecName: Full=Melanoma-associated antigen 4;
DE   AltName: Full=Cancer/testis antigen 1.4;
DE            Short=CT1.4;
DE   AltName: Full=MAGE-4 antigen;
DE   AltName: Full=MAGE-41 antigen;
DE   AltName: Full=MAGE-X2 antigen;
GN   Name=MAGEA4; Synonyms=MAGE4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGA6_HUMAN             Reviewed;         314 AA.
AC   P43360; A8IF93; Q6NW44;
DE   RecName: Full=Melanoma-associated antigen 6;
DE   AltName: Full=Cancer/testis antigen 1.6;
DE            Short=CT1.6;
DE   AltName: Full=MAGE-6 antigen;
DE   AltName: Full=MAGE3B antigen;
GN   Name=MAGEA6; Synonyms=MAGE6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGA1_HUMAN             Reviewed;         309 AA.
AC   P43355; B2RC81; O00346;
DE   RecName: Full=Melanoma-associated antigen 1;
DE   AltName: Full=Antigen MZ2-E;
DE   AltName: Full=Cancer/testis antigen 1.1;
DE            Short=CT1.1;
DE   AltName: Full=MAGE-1 antigen;
GN   Name=MAGEA1; Synonyms=MAGE1, MAGE1A;
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAGA5_HUMAN             Reviewed;         124 AA.
AC   P43359; Q32MD0;
DE   RecName: Full=Melanoma-associated antigen 5;
DE   AltName: Full=Cancer/testis antigen 1.5;
DE            Short=CT1.5;
DE   AltName: Full=MAGE-5 antigen;
GN   Name=MAGEA5; Synonyms=MAGE5;
//
ID   MAGA9_HUMAN             Reviewed;         315 AA.
AC   P43362; A8K8A7; Q7Z5K4; Q92910;
DE   RecName: Full=Melanoma-associated antigen 9;
DE   AltName: Full=Cancer/testis antigen 1.9;
DE            Short=CT1.9;
DE   AltName: Full=MAGE-9 antigen;
GN   Name=MAGEA9; Synonyms=MAGE9, MAGEA9A;
GN   and
GN   Name=MAGEA9B;
//
ID   MAGAB_HUMAN             Reviewed;         429 AA.
AC   P43364; Q5ETU4; Q6ZRZ5;
DE   RecName: Full=Melanoma-associated antigen 11;
DE   AltName: Full=Cancer/testis antigen 1.11;
DE            Short=CT1.11;
DE   AltName: Full=MAGE-11 antigen;
GN   Name=MAGEA11; Synonyms=MAGE11;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGA8_HUMAN             Reviewed;         318 AA.
AC   P43361; Q9BUN9;
DE   RecName: Full=Melanoma-associated antigen 8;
DE   AltName: Full=Cancer/testis antigen 1.8;
DE            Short=CT1.8;
DE   AltName: Full=MAGE-8 antigen;
GN   Name=MAGEA8; Synonyms=MAGE8;
//
ID   MAGAA_HUMAN             Reviewed;         369 AA.
AC   P43363;
DE   RecName: Full=Melanoma-associated antigen 10;
DE   AltName: Full=Cancer/testis antigen 1.10;
DE            Short=CT1.10;
DE   AltName: Full=MAGE-10 antigen;
GN   Name=MAGEA10; Synonyms=MAGE10;
//
ID   MAGAC_HUMAN             Reviewed;         314 AA.
AC   P43365; Q9NSD3;
DE   RecName: Full=Melanoma-associated antigen 12;
DE   AltName: Full=Cancer/testis antigen 1.12;
DE            Short=CT1.12;
DE   AltName: Full=MAGE-12 antigen;
DE   AltName: Full=MAGE12F antigen;
GN   Name=MAGEA12; Synonyms=MAGE12;
//
ID   MAGB1_HUMAN             Reviewed;         347 AA.
AC   P43366; B2RC79; O00601; O75862; Q6FHJ0; Q96CW8;
DE   RecName: Full=Melanoma-associated antigen B1;
DE   AltName: Full=Cancer/testis antigen 3.1;
DE            Short=CT3.1;
DE   AltName: Full=DSS-AHC critical interval MAGE superfamily 10;
DE            Short=DAM10;
DE   AltName: Full=MAGE-B1 antigen;
DE   AltName: Full=MAGE-XP antigen;
GN   Name=MAGEB1; Synonyms=MAGEL1, MAGEXP;
//
ID   MAGB2_HUMAN             Reviewed;         319 AA.
AC   O15479; O75860;
DE   RecName: Full=Melanoma-associated antigen B2;
DE   AltName: Full=Cancer/testis antigen 3.2;
DE            Short=CT3.2;
DE   AltName: Full=DSS-AHC critical interval MAGE superfamily 6;
DE            Short=DAM6;
DE   AltName: Full=MAGE XP-2 antigen;
DE   AltName: Full=MAGE-B2 antigen;
GN   Name=MAGEB2;
//
ID   MAGB3_HUMAN             Reviewed;         346 AA.
AC   O15480; A0AVE4; B3KQ52; O75861;
DE   RecName: Full=Melanoma-associated antigen B3;
DE   AltName: Full=MAGE-B3 antigen;
GN   Name=MAGEB3;
//
ID   MAGB4_HUMAN             Reviewed;         346 AA.
AC   O15481; B2R9G0; Q6FHH4; Q8IZ00;
DE   RecName: Full=Melanoma-associated antigen B4;
DE   AltName: Full=MAGE-B4 antigen;
GN   Name=MAGEB4;
//
ID   MAGB6_HUMAN             Reviewed;         407 AA.
AC   Q8N7X4; Q6GS19; Q9H219;
DE   RecName: Full=Melanoma-associated antigen B6;
DE   AltName: Full=Cancer/testis antigen 3.4;
DE            Short=CT3.4;
DE   AltName: Full=MAGE-B6 antigen;
GN   Name=MAGEB6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGBA_HUMAN             Reviewed;         347 AA.
AC   Q96LZ2; Q494Y6; Q494Y7; Q9BZ78;
DE   RecName: Full=Melanoma-associated antigen B10;
DE   AltName: Full=MAGE-B10 antigen;
GN   Name=MAGEB10;
//
ID   MAGB5_HUMAN             Reviewed;         275 AA.
AC   Q9BZ81;
DE   RecName: Full=Melanoma-associated antigen B5;
DE   AltName: Full=Cancer/testis antigen 3.3;
DE            Short=CT3.3;
DE   AltName: Full=MAGE-B5 antigen;
GN   Name=MAGEB5;
//
ID   MAGBH_HUMAN             Reviewed;         336 AA.
AC   A8MXT2; A6NE98;
DE   RecName: Full=Melanoma-associated antigen B17;
GN   Name=MAGEB17;
//
ID   MAGBG_HUMAN             Reviewed;         324 AA.
AC   A2A368; A8MU30;
DE   RecName: Full=Melanoma-associated antigen B16;
DE   AltName: Full=MAGE-B16 antigen;
GN   Name=MAGEB16;
//
ID   MAGC1_HUMAN             Reviewed;        1142 AA.
AC   O60732; O75451; Q8TCV4;
DE   RecName: Full=Melanoma-associated antigen C1;
DE   AltName: Full=Cancer/testis antigen 7.1;
DE            Short=CT7.1;
DE   AltName: Full=MAGE-C1 antigen;
GN   Name=MAGEC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGC2_HUMAN             Reviewed;         373 AA.
AC   Q9UBF1; Q5JZ00; Q96D45; Q9P1M6; Q9P1M7;
DE   RecName: Full=Melanoma-associated antigen C2;
DE   AltName: Full=Cancer/testis antigen 10;
DE            Short=CT10;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 587;
DE   AltName: Full=MAGE-C2 antigen;
DE   AltName: Full=MAGE-E1 antigen;
GN   Name=MAGEC2; Synonyms=HCA587, MAGEE1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:UniProtKB.
//
ID   MAGBI_HUMAN             Reviewed;         343 AA.
AC   Q96M61;
DE   RecName: Full=Melanoma-associated antigen B18;
DE   AltName: Full=MAGE-B18 antigen;
GN   Name=MAGEB18;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGC3_HUMAN             Reviewed;         643 AA.
AC   Q8TD91; Q3SYA7; Q5JZ43; Q9BZ80;
DE   RecName: Full=Melanoma-associated antigen C3;
DE   AltName: Full=Cancer/testis antigen 7.2;
DE            Short=CT7.2;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 2;
DE   AltName: Full=MAGE-C3 antigen;
GN   Name=MAGEC3; Synonyms=HCA2;
//
ID   MAGD1_HUMAN             Reviewed;         778 AA.
AC   Q9Y5V3; Q5VSH6; Q8IZ84; Q8WY92; Q9H352; Q9HBT4; Q9UF36;
DE   RecName: Full=Melanoma-associated antigen D1;
DE   AltName: Full=MAGE tumor antigen CCF;
DE   AltName: Full=MAGE-D1 antigen;
DE   AltName: Full=Neurotrophin receptor-interacting MAGE homolog;
GN   Name=MAGED1; Synonyms=NRAGE; ORFNames=PP2250, PRO2292;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
//
ID   MAGD2_HUMAN             Reviewed;         606 AA.
AC   Q9UNF1; A6NMX0; O76058; Q5BJF3; Q8NAL6; Q9H218; Q9P0U9; Q9UM52;
DE   RecName: Full=Melanoma-associated antigen D2;
DE   AltName: Full=11B6;
DE   AltName: Full=Breast cancer-associated gene 1 protein;
DE            Short=BCG-1;
DE   AltName: Full=Hepatocellular carcinoma-associated protein JCL-1;
DE   AltName: Full=MAGE-D2 antigen;
GN   Name=MAGED2; Synonyms=BCG1;
//
ID   MAGE1_HUMAN             Reviewed;         957 AA.
AC   Q9HCI5; Q86TG0; Q8TD92; Q9H216;
DE   RecName: Full=Melanoma-associated antigen E1;
DE   AltName: Full=Alpha-dystrobrevin-associated MAGE Protein;
DE            Short=DAMAGE;
DE   AltName: Full=Hepatocellular carcinoma-associated protein 1;
DE   AltName: Full=MAGE-E1 antigen;
GN   Name=MAGEE1; Synonyms=HCA1, KIAA1587;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MAGD4_HUMAN             Reviewed;         741 AA.
AC   Q96JG8; A8K093; Q5HYN6; Q8WXW4; Q9BQ84; Q9BVH1; Q9BYH3; Q9BYH4;
AC   Q9H217;
DE   RecName: Full=Melanoma-associated antigen D4;
DE   AltName: Full=MAGE-D4 antigen;
DE   AltName: Full=MAGE-E1 antigen;
GN   Name=MAGED4; Synonyms=KIAA1859, MAGED4A, MAGEE1;
GN   and
GN   Name=MAGED4B;
//
ID   MAGE2_HUMAN             Reviewed;         523 AA.
AC   Q8TD90; Q5JSI5;
DE   RecName: Full=Melanoma-associated antigen E2;
DE   AltName: Full=Hepatocellular carcinoma-associated protein 3;
DE   AltName: Full=MAGE-E2 antigen;
GN   Name=MAGEE2; Synonyms=HCA3;
//
ID   MAGH1_HUMAN             Reviewed;         219 AA.
AC   Q9H213; B2R8V9; Q5JRJ3; Q9Y5M2;
DE   RecName: Full=Melanoma-associated antigen H1;
DE   AltName: Full=Apoptosis-related protein 1;
DE            Short=APR-1;
DE   AltName: Full=MAGE-H1 antigen;
DE   AltName: Full=Restin;
GN   Name=MAGEH1; Synonyms=APR1;
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
//
ID   MAGI1_HUMAN             Reviewed;        1491 AA.
AC   Q96QZ7; O00309; O43863; O75085; Q96QZ8; Q96QZ9;
DE   RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1;
DE   AltName: Full=Atrophin-1-interacting protein 3;
DE            Short=AIP-3;
DE   AltName: Full=BAI1-associated protein 1;
DE            Short=BAP-1;
DE   AltName: Full=Membrane-associated guanylate kinase inverted 1;
DE            Short=MAGI-1;
DE   AltName: Full=Trinucleotide repeat-containing gene 19 protein;
DE   AltName: Full=WW domain-containing protein 3;
DE            Short=WWP3;
GN   Name=MAGI1; Synonyms=AIP3, BAIAP1, BAP1, TNRC19;
DR   GO; GO:0051393; F:alpha-actinin binding; IPI:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0070997; P:neuron death; IMP:UniProt.
DR   GO; GO:0006461; P:protein complex assembly; NAS:ProtInc.
//
ID   MAGF1_HUMAN             Reviewed;         307 AA.
AC   Q9HAY2; Q9H215;
DE   RecName: Full=Melanoma-associated antigen F1;
DE   AltName: Full=MAGE-F1 antigen;
GN   Name=MAGEF1;
//
ID   MAGG1_HUMAN             Reviewed;         304 AA.
AC   Q96MG7; Q8IW16; Q8TEI6; Q9H214;
DE   RecName: Full=Melanoma-associated antigen G1;
DE   AltName: Full=Hepatocellular carcinoma-associated protein 4;
DE   AltName: Full=MAGE-G1 antigen;
DE   AltName: Full=Necdin-like protein 2;
GN   Name=NDNL2; Synonyms=HCA4, MAGEG1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   MAGI2_HUMAN             Reviewed;        1455 AA.
AC   Q86UL8; A4D1C1; A7E2C3; O60434; O60510; Q86UI7; Q9NP44; Q9UDQ5;
AC   Q9UDU1;
DE   RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2;
DE   AltName: Full=Atrophin-1-interacting protein 1;
DE            Short=AIP-1;
DE   AltName: Full=Atrophin-1-interacting protein A;
DE   AltName: Full=Membrane-associated guanylate kinase inverted 2;
DE            Short=MAGI-2;
GN   Name=MAGI2; Synonyms=ACVRINP1, AIP1, KIAA0705;
DR   GO; GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; ISS:UniProtKB.
DR   GO; GO:0070699; F:type II activin receptor binding; ISS:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0016482; P:cytoplasmic transport; ISS:UniProtKB.
DR   GO; GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0038180; P:nerve growth factor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0003402; P:planar cell polarity pathway involved in axis elongation; NAS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.
DR   GO; GO:0043113; P:receptor clustering; ISS:UniProtKB.
DR   GO; GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.
//
ID   MAGI3_HUMAN             Reviewed;        1506 AA.
AC   Q5TCQ9; Q5TCQ8; Q5TCR0; Q9H2V6; Q9H5Y8; Q9HBC4; Q9HCD8;
DE   RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3;
DE   AltName: Full=Membrane-associated guanylate kinase inverted 3;
DE            Short=MAGI-3;
GN   Name=MAGI3; Synonyms=KIAA1634;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0046939; P:nucleotide phosphorylation; NAS:GOC.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MAGIX_HUMAN             Reviewed;         334 AA.
AC   Q9H6Y5; A6XND4; A8MSX9; B7WP26; Q14C81;
DE   RecName: Full=PDZ domain-containing protein MAGIX;
GN   Name=MAGIX;
//
ID   MAGT1_HUMAN             Reviewed;         335 AA.
AC   Q9H0U3; B2RAR4; D3DTE3; Q53G00; Q8NBN6;
DE   RecName: Full=Magnesium transporter protein 1;
DE            Short=MagT1;
DE   AltName: Full=Implantation-associated protein;
DE            Short=IAP;
DE   Flags: Precursor;
GN   Name=MAGT1; Synonyms=IAG2; ORFNames=PSEC0084, UNQ628/PRO1244;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0015693; P:magnesium ion transport; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; NAS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MAGL2_HUMAN             Reviewed;         529 AA.
AC   Q9UJ55;
DE   RecName: Full=MAGE-like protein 2;
DE   AltName: Full=Necdin-like protein 1;
DE   AltName: Full=Protein nM15;
GN   Name=MAGEL2; Synonyms=NDNL1;
//
ID   MAG_HUMAN               Reviewed;         626 AA.
AC   P20916; B7Z2E5; F5GYC0; Q567S4;
DE   RecName: Full=Myelin-associated glycoprotein;
DE   AltName: Full=Siglec-4a;
DE   Flags: Precursor;
GN   Name=MAG; Synonyms=GMA;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProtKB.
//
ID   MAK16_HUMAN             Reviewed;         300 AA.
AC   Q9BXY0; B2RB44; Q5U5T1; Q86UC4; Q96SY6;
DE   RecName: Full=Protein MAK16 homolog;
DE   AltName: Full=NNP78;
DE   AltName: Full=Protein RBM13;
GN   Name=MAK16; Synonyms=RBM13;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   MAK_HUMAN               Reviewed;         623 AA.
AC   P20794; F1T0K6; G1FL29; Q547D0; Q9NUH7;
DE   RecName: Full=Serine/threonine-protein kinase MAK;
DE            EC=2.7.11.22;
DE   AltName: Full=Male germ cell-associated kinase;
GN   Name=MAK;
DR   GuidetoPHARMACOLOGY; 2061; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAL2_HUMAN              Reviewed;         176 AA.
AC   Q969L2; B2R520; Q6ZMD9;
DE   RecName: Full=Protein MAL2;
GN   Name=MAL2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   MALAT_HUMAN             Reviewed;          57 AA.
AC   Q9UHZ2;
DE   RecName: Full=Metastasis-associated lung adenocarcinoma transcript 1;
GN   Name=MALAT1; ORFNames=PRO1073, PRO2853;
//
ID   MALD1_HUMAN             Reviewed;         173 AA.
AC   Q9BSK0;
DE   RecName: Full=MARVEL domain-containing protein 1;
GN   Name=MARVELD1; Synonyms=MRVLDC1;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   MALD2_HUMAN             Reviewed;         558 AA.
AC   Q8N4S9; A1BQX0; A1BQX1; A8KA97; Q96NM9;
DE   RecName: Full=MARVEL domain-containing protein 2;
DE   AltName: Full=Tricellulin;
GN   Name=MARVELD2; Synonyms=TRIC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0045216; P:cell-cell junction organization; IMP:MGI.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProt.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:MGI.
DR   GO; GO:0070830; P:tight junction assembly; IMP:UniProt.
//
ID   MALD3_HUMAN             Reviewed;         401 AA.
AC   Q96A59; A8K820; H3BQM5; Q96MJ4;
DE   RecName: Full=MARVEL domain-containing protein 3;
GN   Name=MARVELD3; Synonyms=MRVLDC3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0045216; P:cell-cell junction organization; IMP:MGI.
DR   GO; GO:0070830; P:tight junction assembly; IMP:UniProt.
//
ID   MALL_HUMAN              Reviewed;         153 AA.
AC   Q13021; B3KWR6; Q9BTU0;
DE   RecName: Full=MAL-like protein;
DE   AltName: Full=Protein BENE;
GN   Name=MALL; Synonyms=BENE;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042632; P:cholesterol homeostasis; NAS:HGNC.
//
ID   MALR1_HUMAN             Reviewed;        1473 AA.
AC   Q5VYJ5; B7ZBP2;
DE   RecName: Full=MAM and LDL-receptor class A domain-containing protein 1;
GN   Name=MALRD1; Synonyms=C10orf112;
//
ID   MALT1_HUMAN             Reviewed;         824 AA.
AC   Q9UDY8; Q9NTB7; Q9ULX4;
DE   RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1;
DE            EC=3.4.22.-;
DE   AltName: Full=MALT lymphoma-associated translocation;
DE   AltName: Full=Paracaspase;
GN   Name=MALT1; Synonyms=MLT;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.
DR   GO; GO:0001923; P:B-1 B cell differentiation; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; NAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0051168; P:nuclear export; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; NAS:BHF-UCL.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:GOC.
DR   GO; GO:0006508; P:proteolysis; IDA:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0050856; P:regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009620; P:response to fungus; IEA:Ensembl.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IEA:Ensembl.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
//
ID   MAL_HUMAN               Reviewed;         153 AA.
AC   P21145; Q6FH77;
DE   RecName: Full=Myelin and lymphocyte protein;
DE   AltName: Full=T-lymphocyte maturation-associated protein;
GN   Name=MAL;
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:UniProtKB.
DR   GO; GO:0016505; F:peptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019911; F:structural constituent of myelin sheath; IDA:UniProtKB.
DR   GO; GO:0045176; P:apical protein localization; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:UniProtKB.
DR   GO; GO:0001766; P:membrane raft polarization; TAS:UniProtKB.
DR   GO; GO:0042552; P:myelination; NAS:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
//
ID   MAMD1_HUMAN             Reviewed;         774 AA.
AC   Q13495; B2RCQ4; B4DG93; B9EGA5;
DE   RecName: Full=Mastermind-like domain-containing protein 1;
DE   AltName: Full=F18;
DE   AltName: Full=Protein CG1;
GN   Name=MAMLD1; Synonyms=CG1, CXorf6;
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MAMC2_HUMAN             Reviewed;         686 AA.
AC   Q7Z304; Q5VW47; Q8WX43; Q96BM4;
DE   RecName: Full=MAM domain-containing protein 2;
DE   AltName: Full=MAM domain-containing proteoglycan;
DE            Short=Mamcan;
DE   Flags: Precursor;
GN   Name=MAMDC2;
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IEA:Ensembl.
//
ID   MAML3_HUMAN             Reviewed;        1134 AA.
AC   Q96JK9; B2RNU9; B3KVV7;
DE   RecName: Full=Mastermind-like protein 3;
DE            Short=Mam-3;
GN   Name=MAML3; Synonyms=KIAA1816;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MAML2_HUMAN             Reviewed;        1156 AA.
AC   Q8IZL2; A7MD26; Q6AI23; Q6Y3A3; Q8IUL3; Q96JK6;
DE   RecName: Full=Mastermind-like protein 2;
DE            Short=Mam-2;
GN   Name=MAML2; Synonyms=KIAA1819;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MAN1_HUMAN              Reviewed;         911 AA.
AC   Q9Y2U8; Q9NT47; Q9NYA5;
DE   RecName: Full=Inner nuclear membrane protein Man1;
DE   AltName: Full=LEM domain-containing protein 3;
GN   Name=LEMD3; Synonyms=MAN1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
//
ID   MAML1_HUMAN             Reviewed;        1016 AA.
AC   Q92585; Q9NZ12;
DE   RecName: Full=Mastermind-like protein 1;
DE            Short=Mam-1;
GN   Name=MAML1; Synonyms=KIAA0200;
DR   GO; GO:0042605; F:peptide antigen binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0060928; P:atrioventricular node cell development; ISS:BHF-UCL.
DR   GO; GO:0003162; P:atrioventricular node development; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; IGI:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MANBA_HUMAN             Reviewed;         879 AA.
AC   O00462; Q96BC3; Q9NYX9;
DE   RecName: Full=Beta-mannosidase;
DE            EC=3.2.1.25;
DE   AltName: Full=Lysosomal beta A mannosidase;
DE   AltName: Full=Mannanase;
DE            Short=Mannase;
DE   Flags: Precursor;
GN   Name=MANBA; Synonyms=MANB1;
DR   GO; GO:0004567; F:beta-mannosidase activity; TAS:ProtInc.
DR   GO; GO:0005537; F:mannose binding; IEA:Ensembl.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IEA:Ensembl.
DR   GO; GO:0046355; P:mannan catabolic process; IEA:InterPro.
//
ID   MANBL_HUMAN             Reviewed;          85 AA.
AC   Q9NQG1; A8KAA6; E1P5V3;
DE   RecName: Full=Protein MANBAL;
GN   Name=MANBAL;
//
ID   MANEA_HUMAN             Reviewed;         462 AA.
AC   Q5SRI9; A6H8M6; Q5SRJ0; Q6MZV0; Q70JE9; Q7Z3V7; Q8WWX5; Q9H9D2;
DE   RecName: Full=Glycoprotein endo-alpha-1,2-mannosidase;
DE            Short=Endo-alpha mannosidase;
DE            Short=Endomannosidase;
DE            Short=hEndo;
DE            EC=3.2.1.130;
DE   AltName: Full=Mandaselin;
GN   Name=MANEA;
DR   GO; GO:0004569; F:glycoprotein endo-alpha-1,2-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MANEL_HUMAN             Reviewed;         457 AA.
AC   Q5VSG8; Q6DD86; Q6P497; Q8N5P8; Q96G55; Q96N42;
DE   RecName: Full=Glycoprotein endo-alpha-1,2-mannosidase-like protein;
DE            EC=3.2.1.-;
GN   Name=MANEAL;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   MANF_HUMAN              Reviewed;         182 AA.
AC   P55145; Q14CX4; Q86U67; Q96IS4;
DE   RecName: Full=Mesencephalic astrocyte-derived neurotrophic factor;
DE   AltName: Full=Arginine-rich protein;
DE   AltName: Full=Protein ARMET;
DE   Flags: Precursor;
GN   Name=MANF; Synonyms=ARMET, ARP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0002014; P:vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure; IEA:Ensembl.
//
ID   MANS1_HUMAN             Reviewed;         431 AA.
AC   Q9H8J5; Q8NEC1;
DE   RecName: Full=MANSC domain-containing protein 1;
DE   AltName: Full=Loss of heterozygosity 12 chromosomal region 3 protein;
DE   Flags: Precursor;
GN   Name=MANSC1; Synonyms=LOH12CR3; ORFNames=UNQ316/PRO361;
//
ID   MANS4_HUMAN             Reviewed;         340 AA.
AC   A6NHS7;
DE   RecName: Full=MANSC domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=MANSC4;
//
ID   MAOM_HUMAN              Reviewed;         584 AA.
AC   P23368; B2R8J2; Q9BWL6; Q9BYG1; Q9H4B2;
DE   RecName: Full=NAD-dependent malic enzyme, mitochondrial;
DE            Short=NAD-ME;
DE            EC=1.1.1.38;
DE   AltName: Full=Malic enzyme 2;
DE   Flags: Precursor;
GN   Name=ME2;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004471; F:malate dehydrogenase (decarboxylating) (NAD+) activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006108; P:malate metabolic process; IEA:InterPro.
//
ID   MAON_HUMAN              Reviewed;         604 AA.
AC   Q16798; Q8TBJ0;
DE   RecName: Full=NADP-dependent malic enzyme, mitochondrial;
DE            Short=NADP-ME;
DE            EC=1.1.1.40;
DE   AltName: Full=Malic enzyme 3;
DE   Flags: Precursor;
GN   Name=ME3;
DR   GO; GO:0048037; F:cofactor binding; TAS:UniProtKB.
DR   GO; GO:0004471; F:malate dehydrogenase (decarboxylating) (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004473; F:malate dehydrogenase (decarboxylating) (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0004470; F:malic enzyme activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009060; P:aerobic respiration; TAS:UniProtKB.
DR   GO; GO:0006108; P:malate metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0072592; P:oxygen metabolic process; TAS:UniProtKB.
DR   GO; GO:0006090; P:pyruvate metabolic process; IDA:UniProtKB.
//
ID   MAOX_HUMAN              Reviewed;         572 AA.
AC   P48163; Q16797; Q16855; Q53F72; Q5VWA2; Q9BWX8; Q9H1W3; Q9UIY4;
DE   RecName: Full=NADP-dependent malic enzyme;
DE            Short=NADP-ME;
DE            EC=1.1.1.40;
DE   AltName: Full=Malic enzyme 1;
GN   Name=ME1;
DR   GO; GO:0043531; F:ADP binding; TAS:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004471; F:malate dehydrogenase (decarboxylating) (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004473; F:malate dehydrogenase (decarboxylating) (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0004470; F:malic enzyme activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; TAS:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; TAS:UniProtKB.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006108; P:malate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006741; P:NADP biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; TAS:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MAP10_HUMAN             Reviewed;         905 AA.
AC   Q9P2G4; A8K2F1; Q32MI1; Q58EZ9; Q5VV83;
DE   RecName: Full=Microtubule-associated protein 10;
DE   AltName: Full=Microtubule regulator of 120 KDa;
GN   Name=MAP10; Synonyms=KIAA1383, MTR120;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IMP:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
DR   GO; GO:0051256; P:spindle midzone assembly involved in mitosis; IMP:UniProtKB.
//
ID   MAP11_HUMAN             Reviewed;         386 AA.
AC   P53582; B4E2E6;
DE   RecName: Full=Methionine aminopeptidase 1;
DE            Short=MAP 1;
DE            Short=MetAP 1;
DE            EC=3.4.11.18;
DE   AltName: Full=Peptidase M 1;
GN   Name=METAP1; Synonyms=KIAA0094;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008235; F:metalloexopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0031365; P:N-terminal protein amino acid modification; TAS:HGNC.
DR   GO; GO:0018206; P:peptidyl-methionine modification; TAS:HGNC.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0070084; P:protein initiator methionine removal; IEA:UniProtKB-HAMAP.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; TAS:HGNC.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
//
ID   MAP12_HUMAN             Reviewed;         335 AA.
AC   Q6UB28; Q1WNX3;
DE   RecName: Full=Methionine aminopeptidase 1D, mitochondrial;
DE            Short=MAP 1D;
DE            Short=MetAP 1D;
DE            EC=3.4.11.18;
DE   AltName: Full=Methionyl aminopeptidase type 1D, mitochondrial;
DE   AltName: Full=Peptidase M 1D;
DE   Flags: Precursor;
GN   Name=METAP1D; Synonyms=MAP1D;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008235; F:metalloexopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0031365; P:N-terminal protein amino acid modification; TAS:HGNC.
DR   GO; GO:0018206; P:peptidyl-methionine modification; TAS:HGNC.
DR   GO; GO:0070084; P:protein initiator methionine removal; IEA:UniProtKB-HAMAP.
//
ID   MAP1A_HUMAN             Reviewed;        2803 AA.
AC   P78559; O95643; Q12973; Q15882; Q9UJT4;
DE   RecName: Full=Microtubule-associated protein 1A;
DE            Short=MAP-1A;
DE   AltName: Full=Proliferation-related protein p80;
DE   Contains:
DE     RecName: Full=MAP1A heavy chain;
DE   Contains:
DE     RecName: Full=MAP1 light chain LC2;
GN   Name=MAP1A; Synonyms=MAP1L;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   MAP1B_HUMAN             Reviewed;        2468 AA.
AC   P46821; A2BDK5;
DE   RecName: Full=Microtubule-associated protein 1B;
DE            Short=MAP-1B;
DE   Contains:
DE     RecName: Full=MAP1B heavy chain;
DE   Contains:
DE     RecName: Full=MAP1 light chain LC1;
GN   Name=MAP1B;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0009987; P:cellular process; IDA:DFLAT.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0061162; P:establishment of monopolar cell polarity; IEA:Ensembl.
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; IEA:Ensembl.
DR   GO; GO:0032387; P:negative regulation of intracellular transport; IEA:Ensembl.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
//
ID   MAP1S_HUMAN             Reviewed;        1059 AA.
AC   Q66K74; Q27QB1; Q6NXF1; Q8N3L8; Q8N3W5; Q8NI88; Q96H94; Q96IT4;
AC   Q96SP8; Q9BRC6; Q9H928; Q9NVK7;
DE   RecName: Full=Microtubule-associated protein 1S;
DE            Short=MAP-1S;
DE   AltName: Full=BPY2-interacting protein 1;
DE   AltName: Full=Microtubule-associated protein 8;
DE   AltName: Full=Variable charge Y chromosome 2-interacting protein 1;
DE            Short=VCY2-interacting protein 1;
DE            Short=VCY2IP-1;
DE   Contains:
DE     RecName: Full=MAP1S heavy chain;
DE   Contains:
DE     RecName: Full=MAP1S light chain;
GN   Name=MAP1S; Synonyms=BPY2IP1, C19orf5, MAP8, VCY2IP1;
DR   GO; GO:0051015; F:actin filament binding; IDA:HGNC.
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:HGNC.
DR   GO; GO:0003677; F:DNA binding; IDA:HGNC.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:HGNC.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; TAS:BHF-UCL.
DR   GO; GO:0007420; P:brain development; ISS:HGNC.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:BHF-UCL.
DR   GO; GO:0001578; P:microtubule bundle formation; IMP:HGNC.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; TAS:HGNC.
DR   GO; GO:0007399; P:nervous system development; ISS:HGNC.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEP:HGNC.
//
ID   MAP2_HUMAN              Reviewed;         478 AA.
AC   P50579; B2RDI8;
DE   RecName: Full=Methionine aminopeptidase 2;
DE            Short=MAP 2;
DE            Short=MetAP 2;
DE            EC=3.4.11.18;
DE   AltName: Full=Initiation factor 2-associated 67 kDa glycoprotein;
DE            Short=p67;
DE            Short=p67eIF2;
DE   AltName: Full=Peptidase M;
GN   Name=METAP2; Synonyms=MNPEP, P67EIF2;
DR   GuidetoPHARMACOLOGY; 1573; -.
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0031365; P:N-terminal protein amino acid modification; IDA:HGNC.
DR   GO; GO:0018206; P:peptidyl-methionine modification; IDA:HGNC.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0070084; P:protein initiator methionine removal; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016485; P:protein processing; IDA:HGNC.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
//
ID   MAP4_HUMAN              Reviewed;        1152 AA.
AC   P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9;
DE   RecName: Full=Microtubule-associated protein 4;
DE            Short=MAP-4;
GN   Name=MAP4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0051301; P:cell division; IMP:MGI.
DR   GO; GO:0051294; P:establishment of spindle orientation; IMP:MGI.
DR   GO; GO:0051012; P:microtubule sliding; IMP:MGI.
DR   GO; GO:0007052; P:mitotic spindle organization; IMP:MGI.
//
ID   MAP6_HUMAN              Reviewed;         813 AA.
AC   Q96JE9; A7E2A1; Q6P3T0; Q6ZWB8;
DE   RecName: Full=Microtubule-associated protein 6;
DE            Short=MAP-6;
DE   AltName: Full=Stable tubule-only polypeptide;
DE            Short=STOP;
GN   Name=MAP6; Synonyms=KIAA1878;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; IMP:UniProtKB.
DR   GO; GO:0032418; P:lysosome localization; IMP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MAP7_HUMAN              Reviewed;         749 AA.
AC   Q14244; B7Z290; B7Z400; B7Z5S7; B7Z9U7; C9JPS0; E9PCP3; F5H1E2;
AC   Q7Z6S0; Q8TAU5; Q9NY82; Q9NY83;
DE   RecName: Full=Ensconsin;
DE   AltName: Full=Epithelial microtubule-associated protein of 115 kDa;
DE            Short=E-MAP-115;
DE   AltName: Full=Microtubule-associated protein 7;
DE            Short=MAP-7;
GN   Name=MAP7;
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0006997; P:nucleus organization; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0006970; P:response to osmotic stress; ISS:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   MAP9_HUMAN              Reviewed;         647 AA.
AC   Q49MG5; Q4W5I7; Q68DU1; Q9H781; Q9H7B6;
DE   RecName: Full=Microtubule-associated protein 9;
DE   AltName: Full=Aster-associated protein;
GN   Name=MAP9; Synonyms=ASAP;
DR   GO; GO:0000910; P:cytokinesis; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007088; P:regulation of mitosis; IEA:InterPro.
DR   GO; GO:0051225; P:spindle assembly; IEA:InterPro.
//
ID   MAPK2_HUMAN             Reviewed;         400 AA.
AC   P49137; Q5SY30; Q5SY41; Q8IYD6;
DE   RecName: Full=MAP kinase-activated protein kinase 2;
DE            Short=MAPK-activated protein kinase 2;
DE            Short=MAPKAP kinase 2;
DE            Short=MAPKAP-K2;
DE            Short=MAPKAPK-2;
DE            Short=MK-2;
DE            Short=MK2;
DE            EC=2.7.11.1;
GN   Name=MAPKAPK2;
DR   GuidetoPHARMACOLOGY; 2094; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0044351; P:macropinocytosis; ISS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; TAS:ProtInc.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0032675; P:regulation of interleukin-6 production; ISS:UniProtKB.
DR   GO; GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   MAPK3_HUMAN             Reviewed;         382 AA.
AC   Q16644; B5BU67;
DE   RecName: Full=MAP kinase-activated protein kinase 3;
DE            Short=MAPK-activated protein kinase 3;
DE            Short=MAPKAP kinase 3;
DE            Short=MAPKAP-K3;
DE            Short=MAPKAPK-3;
DE            Short=MK-3;
DE            EC=2.7.11.1;
DE   AltName: Full=Chromosome 3p kinase;
DE            Short=3pK;
GN   Name=MAPKAPK3;
DR   GuidetoPHARMACOLOGY; 2095; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0044351; P:macropinocytosis; ISS:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0034097; P:response to cytokine; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MAPK5_HUMAN             Reviewed;         473 AA.
AC   Q8IW41; B3KVA5; O60491; Q86X46; Q9BVX9; Q9UG86;
DE   RecName: Full=MAP kinase-activated protein kinase 5;
DE            Short=MAPK-activated protein kinase 5;
DE            Short=MAPKAP kinase 5;
DE            Short=MAPKAP-K5;
DE            Short=MAPKAPK-5;
DE            Short=MK-5;
DE            Short=MK5;
DE            EC=2.7.11.1;
DE   AltName: Full=p38-regulated/activated protein kinase;
DE            Short=PRAK;
GN   Name=MAPKAPK5; Synonyms=PRAK;
DR   GuidetoPHARMACOLOGY; 2096; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:GOC.
DR   GO; GO:0000165; P:MAPK cascade; TAS:GOC.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0090400; P:stress-induced premature senescence; IDA:UniProtKB.
//
ID   MAR1_HUMAN              Reviewed;         118 AA.
AC   Q16655; Q6ICU4;
DE   RecName: Full=Melanoma antigen recognized by T-cells 1;
DE            Short=MART-1;
DE   AltName: Full=Antigen LB39-AA;
DE   AltName: Full=Antigen SK29-AA;
DE   AltName: Full=Protein Melan-A;
GN   Name=MLANA; Synonyms=MART1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   MARC1_HUMAN             Reviewed;         337 AA.
AC   Q5VT66; A8K447; B2D078; Q5VVS9; Q5VVT0; Q5VVT1; Q8N9P5; Q96FN8;
AC   Q9H6C7;
DE   RecName: Full=Mitochondrial amidoxime-reducing component 1;
DE            Short=mARC1;
DE            EC=1.-.-.-;
DE   AltName: Full=Molybdenum cofactor sulfurase C-terminal domain-containing protein 1;
DE            Short=MOSC domain-containing protein 1;
DE            Short=Moco sulfurase C-terminal domain-containing protein 1;
GN   Name=MARC1; Synonyms=MOSC1;
DR   GO; GO:0030151; F:molybdenum ion binding; IDA:UniProtKB.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IDA:UniProtKB.
DR   GO; GO:0008940; F:nitrate reductase activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0051410; P:detoxification of nitrogen compound; NAS:UniProtKB.
DR   GO; GO:0042126; P:nitrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
//
ID   MARC2_HUMAN             Reviewed;         335 AA.
AC   Q969Z3; B2D0R5; D3DTB3; Q0JSK7; Q5VT67; Q5VXC7; Q7L317; Q9H066;
AC   Q9NWU0;
DE   RecName: Full=Mitochondrial amidoxime reducing component 2;
DE            Short=mARC2;
DE            EC=1.-.-.-;
DE   AltName: Full=Molybdenum cofactor sulfurase C-terminal domain-containing protein 2;
DE            Short=MOSC domain-containing protein 2;
DE            Short=Moco sulfurase C-terminal domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=MARC2; Synonyms=MOSC2;
DR   GO; GO:0030151; F:molybdenum ion binding; IDA:UniProtKB.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IDA:UniProtKB.
DR   GO; GO:0008940; F:nitrate reductase activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0051410; P:detoxification of nitrogen compound; NAS:UniProtKB.
DR   GO; GO:0042126; P:nitrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
//
ID   MARCO_HUMAN             Reviewed;         520 AA.
AC   Q9UEW3; Q9Y5S3;
DE   RecName: Full=Macrophage receptor MARCO;
DE   AltName: Full=Macrophage receptor with collagenous structure;
DE   AltName: Full=Scavenger receptor class A member 2;
GN   Name=MARCO; Synonyms=SCARA2;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0008329; F:signaling pattern recognition receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; TAS:GOC.
//
ID   MARCS_HUMAN             Reviewed;         332 AA.
AC   P29966; E1P560; Q2LA83; Q5TDB7;
DE   RecName: Full=Myristoylated alanine-rich C-kinase substrate;
DE            Short=MARCKS;
DE   AltName: Full=Protein kinase C substrate, 80 kDa protein, light chain;
DE            Short=80K-L protein;
DE            Short=PKCSL;
GN   Name=MARCKS; Synonyms=MACS, PRKCSL;
DR   GO; GO:0051015; F:actin filament binding; TAS:ProtInc.
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MARE1_HUMAN             Reviewed;         268 AA.
AC   Q15691; B2R6I7; E1P5M8; Q3KQS8;
DE   RecName: Full=Microtubule-associated protein RP/EB family member 1;
DE   AltName: Full=APC-binding protein EB1;
DE   AltName: Full=End-binding protein 1;
DE            Short=EB1;
GN   Name=MAPRE1;
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0035372; P:protein localization to microtubule; IDA:UniProtKB.
//
ID   MARE2_HUMAN             Reviewed;         327 AA.
AC   Q15555; B2RE21; B3KR39; B7Z2L3; E9PHR3; F5H1V8; Q9UQ33;
DE   RecName: Full=Microtubule-associated protein RP/EB family member 2;
DE   AltName: Full=APC-binding protein EB2;
DE   AltName: Full=End-binding protein 2;
DE            Short=EB2;
GN   Name=MAPRE2; Synonyms=RP1;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MARE3_HUMAN             Reviewed;         281 AA.
AC   Q9UPY8; B7WPK5; O00265; Q6FHB0; Q6FI15; Q9BZP7; Q9BZP8;
DE   RecName: Full=Microtubule-associated protein RP/EB family member 3;
DE   AltName: Full=EB1 protein family member 3;
DE            Short=EBF3;
DE   AltName: Full=End-binding protein 3;
DE            Short=EB3;
DE   AltName: Full=RP3;
GN   Name=MAPRE3;
DR   GO; GO:0008017; F:microtubule binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
//
ID   MARF1_HUMAN             Reviewed;        1742 AA.
AC   Q9Y4F3; A8MSK2; B2RNX2; B4DYY9; B7ZMG1; B7ZMG2; F8VV09; Q6P1R6;
AC   Q8WYR2; Q9Y4J9;
DE   RecName: Full=Meiosis arrest female protein 1;
DE   AltName: Full=Limkain-b1;
GN   Name=KIAA0430; Synonyms=LKAP, MARF1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0007143; P:female meiotic division; ISS:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0048477; P:oogenesis; ISS:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; ISS:UniProtKB.
//
ID   MARH1_HUMAN             Reviewed;         289 AA.
AC   Q8TCQ1; D3DP29; Q9NWR0;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH1;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 1;
DE   AltName: Full=Membrane-associated RING-CH protein I;
DE            Short=MARCH-I;
DE   AltName: Full=RING finger protein 171;
GN   Name=MARCH1; Synonyms=RNF171;
DR   GO; GO:0042287; F:MHC protein binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
//
ID   MARH2_HUMAN             Reviewed;         246 AA.
AC   Q9P0N8; A6NP10; Q5H785; Q8N5A3; Q96B78;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH2;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 2;
DE   AltName: Full=Membrane-associated RING-CH protein II;
DE            Short=MARCH-II;
DE   AltName: Full=RING finger protein 172;
GN   Name=MARCH2; Synonyms=RNF172; ORFNames=HSPC240;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   MARH3_HUMAN             Reviewed;         253 AA.
AC   Q86UD3; A8K264;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH3;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 3;
DE   AltName: Full=Membrane-associated RING-CH protein III;
DE            Short=MARCH-III;
DE   AltName: Full=RING finger protein 173;
GN   Name=MARCH3; Synonyms=RNF173;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MARH4_HUMAN             Reviewed;         410 AA.
AC   Q9P2E8; Q4KMN7; Q86WR8;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH4;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 4;
DE   AltName: Full=Membrane-associated RING-CH protein IV;
DE            Short=MARCH-IV;
DE   AltName: Full=RING finger protein 174;
DE   Flags: Precursor;
GN   Name=MARCH4; Synonyms=KIAA1399, RNF174;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MARH5_HUMAN             Reviewed;         278 AA.
AC   Q9NX47;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH5;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 5;
DE   AltName: Full=Membrane-associated RING-CH protein V;
DE            Short=MARCH-V;
DE   AltName: Full=Mitochondrial ubiquitin ligase;
DE            Short=MITOL;
DE   AltName: Full=RING finger protein 153;
GN   Name=MARCH5; Synonyms=RNF153;
DR   GO; GO:0051020; F:GTPase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0090344; P:negative regulation of cell aging; IMP:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070585; P:protein localization to mitochondrion; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0090140; P:regulation of mitochondrial fission; IMP:UniProtKB.
//
ID   MARH6_HUMAN             Reviewed;         910 AA.
AC   O60337; A5PKZ4; B4DKJ2; B4DT33; D3DTC8; O14670; Q86X77;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH6;
DE            EC=6.3.2.-;
DE   AltName: Full=Doa10 homolog;
DE   AltName: Full=Membrane-associated RING finger protein 6;
DE   AltName: Full=Membrane-associated RING-CH protein VI;
DE            Short=MARCH-VI;
DE   AltName: Full=Protein TEB-4;
DE   AltName: Full=RING finger protein 176;
GN   Name=MARCH6; Synonyms=KIAA0597, RNF176, TEB4;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
//
ID   MARH7_HUMAN             Reviewed;         704 AA.
AC   Q9H992; A8K9X1; B7Z7P5; D3DPB0; Q53GQ1; Q9BTR9;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH7;
DE            EC=6.3.2.-;
DE   AltName: Full=Axotrophin;
DE   AltName: Full=Membrane-associated RING finger protein 7;
DE   AltName: Full=Membrane-associated RING-CH protein VII;
DE            Short=MARCH-VII;
DE   AltName: Full=RING finger protein 177;
GN   Name=MARCH7; Synonyms=AXOT, RNF177;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MARH8_HUMAN             Reviewed;         291 AA.
AC   Q5T0T0; B2R8E7; Q5T0S8; Q8TC72;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH8;
DE            EC=6.3.2.-;
DE   AltName: Full=Cellular modulator of immune recognition;
DE            Short=c-MIR;
DE   AltName: Full=Membrane-associated RING finger protein 8;
DE   AltName: Full=Membrane-associated RING-CH protein VIII;
DE            Short=MARCH-VIII;
DE   AltName: Full=RING finger protein 178;
GN   Name=MARCH8; Synonyms=MIR, RNF178;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002495; P:antigen processing and presentation of peptide antigen via MHC class II; IEA:Ensembl.
DR   GO; GO:0045347; P:negative regulation of MHC class II biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
//
ID   MARH9_HUMAN             Reviewed;         346 AA.
AC   Q86YJ5; B2R9U9; Q86VN5; Q96GG2;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH9;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 9;
DE   AltName: Full=Membrane-associated RING-CH protein IX;
DE            Short=MARCH-IX;
DE   AltName: Full=RING finger protein 179;
GN   Name=MARCH9; Synonyms=RNF179;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MARHB_HUMAN             Reviewed;         402 AA.
AC   A6NNE9; A7E2S6;
DE   RecName: Full=E3 ubiquitin-protein ligase MARCH11;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 11;
DE   AltName: Full=Membrane-associated RING-CH protein XI;
DE            Short=MARCH-XI;
GN   Name=MARCH11;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MARHA_HUMAN             Reviewed;         808 AA.
AC   Q8NA82; D3DU09; Q8IYS7; Q8N7Z7;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase MARCH10;
DE            EC=6.3.2.-;
DE   AltName: Full=Membrane-associated RING finger protein 10;
DE   AltName: Full=Membrane-associated RING-CH protein X;
DE            Short=MARCH-X;
DE   AltName: Full=RING finger protein 190;
GN   Name=MARCH10; Synonyms=RNF190;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MARK1_HUMAN             Reviewed;         795 AA.
AC   Q9P0L2; D3DTB0; D3DTB1; Q2HIY1; Q5VTF9; Q5VTG0; Q96SW9; Q9P251;
DE   RecName: Full=Serine/threonine-protein kinase MARK1;
DE            EC=2.7.11.1;
DE            EC=2.7.11.26;
DE   AltName: Full=MAP/microtubule affinity-regulating kinase 1;
DE   AltName: Full=PAR1 homolog c;
DE            Short=Par-1c;
DE            Short=Par1c;
GN   Name=MARK1; Synonyms=KIAA1477, MARK;
DR   GuidetoPHARMACOLOGY; 2097; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   MARK2_HUMAN             Reviewed;         788 AA.
AC   Q7KZI7; Q15449; Q15524; Q5XGA3; Q68A18; Q96HB3; Q96RG0;
DE   RecName: Full=Serine/threonine-protein kinase MARK2;
DE            EC=2.7.11.1;
DE            EC=2.7.11.26;
DE   AltName: Full=ELKL motif kinase 1;
DE            Short=EMK-1;
DE   AltName: Full=MAP/microtubule affinity-regulating kinase 2;
DE   AltName: Full=PAR1 homolog;
DE   AltName: Full=PAR1 homolog b;
DE            Short=Par-1b;
DE            Short=Par1b;
GN   Name=MARK2; Synonyms=EMK1;
DR   GuidetoPHARMACOLOGY; 2098; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; IDA:UniProtKB.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; IMP:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   MARK3_HUMAN             Reviewed;         753 AA.
AC   P27448; O60219; Q86TT8; Q8TB41; Q8WX83; Q96RG1; Q9UMY9; Q9UN34;
DE   RecName: Full=MAP/microtubule affinity-regulating kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=C-TAK1;
DE            Short=cTAK1;
DE   AltName: Full=Cdc25C-associated protein kinase 1;
DE   AltName: Full=ELKL motif kinase 2;
DE            Short=EMK-2;
DE   AltName: Full=Protein kinase STK10;
DE   AltName: Full=Ser/Thr protein kinase PAR-1;
DE            Short=Par-1a;
DE   AltName: Full=Serine/threonine-protein kinase p78;
GN   Name=MARK3; Synonyms=CTAK1, EMK2;
DR   GuidetoPHARMACOLOGY; 2099; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
//
ID   MARK4_HUMAN             Reviewed;         752 AA.
AC   Q96L34; Q8NG37; Q96JG7; Q96SQ2; Q9BYD8;
DE   RecName: Full=MAP/microtubule affinity-regulating kinase 4;
DE            EC=2.7.11.1;
DE   AltName: Full=MAP/microtubule affinity-regulating kinase-like 1;
GN   Name=MARK4; Synonyms=KIAA1860, MARKL1;
DR   GuidetoPHARMACOLOGY; 2100; -.
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; NAS:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IEP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IDA:UniProtKB.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:UniProtKB.
//
ID   MAS1L_HUMAN             Reviewed;         378 AA.
AC   P35410; Q5SUN5;
DE   RecName: Full=Mas-related G-protein coupled receptor MRG;
DE            Short=MAS-R;
DE   AltName: Full=MAS1-like;
GN   Name=MAS1L; Synonyms=MRG;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
//
ID   MASP1_HUMAN             Reviewed;         699 AA.
AC   P48740; A8K542; A8K6M1; B4E2L7; O95570; Q68D21; Q8IUV8; Q96RS4;
AC   Q9UF09;
DE   RecName: Full=Mannan-binding lectin serine protease 1;
DE            EC=3.4.21.-;
DE   AltName: Full=Complement factor MASP-3;
DE   AltName: Full=Complement-activating component of Ra-reactive factor;
DE   AltName: Full=Mannose-binding lectin-associated serine protease 1;
DE            Short=MASP-1;
DE   AltName: Full=Mannose-binding protein-associated serine protease;
DE   AltName: Full=Ra-reactive factor serine protease p100;
DE            Short=RaRF;
DE   AltName: Full=Serine protease 5;
DE   Contains:
DE     RecName: Full=Mannan-binding lectin serine protease 1 heavy chain;
DE   Contains:
DE     RecName: Full=Mannan-binding lectin serine protease 1 light chain;
DE   Flags: Precursor;
GN   Name=MASP1; Synonyms=CRARF, CRARF1, PRSS5;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0001867; P:complement activation, lectin pathway; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045916; P:negative regulation of complement activation; IDA:UniProtKB.
//
ID   MASP2_HUMAN             Reviewed;         686 AA.
AC   O00187; A8K458; A8MWJ2; O75754; Q5TEQ5; Q5TER0; Q96QG4; Q9BZH0;
AC   Q9H498; Q9H499; Q9UBP3; Q9UC48; Q9ULC7; Q9UMV3; Q9Y270;
DE   RecName: Full=Mannan-binding lectin serine protease 2;
DE            EC=3.4.21.104;
DE   AltName: Full=MBL-associated serine protease 2;
DE   AltName: Full=Mannose-binding protein-associated serine protease 2;
DE            Short=MASP-2;
DE   Contains:
DE     RecName: Full=Mannan-binding lectin serine protease 2 A chain;
DE   Contains:
DE     RecName: Full=Mannan-binding lectin serine protease 2 B chain;
DE   Flags: Precursor;
GN   Name=MASP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0001867; P:complement activation, lectin pathway; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   MAST1_HUMAN             Reviewed;        1570 AA.
AC   Q9Y2H9; O00114; Q8N6X0;
DE   RecName: Full=Microtubule-associated serine/threonine-protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Syntrophin-associated serine/threonine-protein kinase;
GN   Name=MAST1; Synonyms=KIAA0973, SAST;
DR   GuidetoPHARMACOLOGY; 1510; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
//
ID   MAST2_HUMAN             Reviewed;        1798 AA.
AC   Q6P0Q8; O94899; Q5VT07; Q5VT08; Q7LGC4; Q8NDG1; Q96B94; Q9BYE8;
DE   RecName: Full=Microtubule-associated serine/threonine-protein kinase 2;
DE            EC=2.7.11.1;
GN   Name=MAST2; Synonyms=KIAA0807, MAST205;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045075; P:regulation of interleukin-12 biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0048515; P:spermatid differentiation; ISS:UniProtKB.
//
ID   MAST3_HUMAN             Reviewed;        1309 AA.
AC   O60307; Q7LDZ8; Q9UPI0;
DE   RecName: Full=Microtubule-associated serine/threonine-protein kinase 3;
DE            EC=2.7.11.1;
GN   Name=MAST3; Synonyms=KIAA0561;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   MAST4_HUMAN             Reviewed;        2626 AA.
AC   O15021; A6NL49; B5ME48; Q05EE6; Q6ZN07; Q8N4X4; Q96LY3;
DE   RecName: Full=Microtubule-associated serine/threonine-protein kinase 4;
DE            EC=2.7.11.1;
GN   Name=MAST4; Synonyms=KIAA0303;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   MASTR_HUMAN             Reviewed;         415 AA.
AC   Q6ZN01; B7ZKX4; Q3KQU9; Q8N9Y3;
DE   RecName: Full=MEF2-activating motif and SAP domain-containing transcriptional regulator;
DE   AltName: Full=MEF2-activating SAP transcriptional regulatory protein;
GN   Name=MAMSTR; Synonyms=MASTR;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   MASU1_HUMAN             Reviewed;         234 AA.
AC   Q96EH3; A4D154;
DE   RecName: Full=Mitochondrial assembly of ribosomal large subunit protein 1;
GN   Name=MALSU1; Synonyms=C7orf30;
DR   GO; GO:0070130; P:negative regulation of mitochondrial translation; IDA:UniProtKB.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
//
ID   MAS_HUMAN               Reviewed;         325 AA.
AC   P04201; E1P5B3; Q2TBC9; Q6FG47;
DE   RecName: Full=Proto-oncogene Mas;
GN   Name=MAS1; Synonyms=MAS;
DR   GuidetoPHARMACOLOGY; 150; -.
DR   GO; GO:0001595; F:angiotensin receptor activity; ISS:UniProtKB.
DR   GO; GO:0004945; F:angiotensin type II receptor activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; ISS:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0060732; P:positive regulation of inositol phosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0070528; P:protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0034698; P:response to gonadotropin; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   MAT1_HUMAN              Reviewed;         309 AA.
AC   P51948; G3V1U8; Q15817; Q6ICQ7;
DE   RecName: Full=CDK-activating kinase assembly factor MAT1;
DE   AltName: Full=CDK7/cyclin-H assembly factor;
DE   AltName: Full=Cyclin-G1-interacting protein;
DE   AltName: Full=Menage a trois;
DE   AltName: Full=RING finger protein 66;
DE   AltName: Full=RING finger protein MAT1;
DE   AltName: Full=p35;
DE   AltName: Full=p36;
GN   Name=MNAT1; Synonyms=CAP35, MAT1, RNF66;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0007512; P:adult heart development; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   MAT2B_HUMAN             Reviewed;         334 AA.
AC   Q9NZL9; B2R5Y6; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89;
AC   Q9H3E1; Q9UJ54;
DE   RecName: Full=Methionine adenosyltransferase 2 subunit beta;
DE   AltName: Full=Methionine adenosyltransferase II beta;
DE            Short=MAT II beta;
DE   AltName: Full=Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase;
GN   Name=MAT2B; Synonyms=TGR;
GN   ORFNames=MSTP045, Nbla02999, UNQ2435/PRO4995;
DR   GO; GO:0008831; F:dTDP-4-dehydrorhamnose reductase activity; IEA:InterPro.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0048270; F:methionine adenosyltransferase regulator activity; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0006556; P:S-adenosylmethionine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   MATK_HUMAN              Reviewed;         507 AA.
AC   P42679; B3KNZ9; Q9NST8;
DE   RecName: Full=Megakaryocyte-associated tyrosine-protein kinase;
DE            EC=2.7.10.2;
DE   AltName: Full=CSK homologous kinase;
DE            Short=CHK;
DE   AltName: Full=Hematopoietic consensus tyrosine-lacking kinase;
DE   AltName: Full=Protein kinase HYL;
DE   AltName: Full=Tyrosine-protein kinase CTK;
GN   Name=MATK; Synonyms=CTK, HYL;
DR   GuidetoPHARMACOLOGY; 2101; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   MATN1_HUMAN             Reviewed;         496 AA.
AC   P21941; B2R7E3; Q5TBB9;
DE   RecName: Full=Cartilage matrix protein;
DE   AltName: Full=Matrilin-1;
DE   Flags: Precursor;
GN   Name=MATN1; Synonyms=CMP, CRTM;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0003429; P:growth plate cartilage chondrocyte morphogenesis; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:Ensembl.
//
ID   MATN2_HUMAN             Reviewed;         956 AA.
AC   O00339; A8K106; E7EW74; E9PD48; E9PGL2; Q6UWA5; Q7Z5X1; Q8NDE6;
AC   Q96FT5; Q9NSZ1;
DE   RecName: Full=Matrilin-2;
DE   Flags: Precursor;
GN   Name=MATN2; ORFNames=UNQ193/PRO219;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0031104; P:dendrite regeneration; IEA:Ensembl.
DR   GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
//
ID   MATN3_HUMAN             Reviewed;         486 AA.
AC   O15232; B2CPU0; Q4ZG02;
DE   RecName: Full=Matrilin-3;
DE   Flags: Precursor;
GN   Name=MATN3;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   MATN4_HUMAN             Reviewed;         622 AA.
AC   O95460; A6NH94; A6NKN5; Q5QPU2; Q5QPU3; Q5QPU4; Q8N2M5; Q8N2M7;
AC   Q9H1F8; Q9H1F9;
DE   RecName: Full=Matrilin-4;
DE   Flags: Precursor;
GN   Name=MATN4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
//
ID   MATR3_HUMAN             Reviewed;         847 AA.
AC   P43243; B7ZAV5; D3DQC3; Q9UHW0; Q9UQ27;
DE   RecName: Full=Matrin-3;
GN   Name=MATR3; Synonyms=KIAA0723;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MAVS_HUMAN              Reviewed;         540 AA.
AC   Q7Z434; A8K6X0; B2BD33; B2BD34; F5H6C8; Q2HWT5; Q3I0Y2; Q5T7I6;
AC   Q86VY7; Q9H1H3; Q9H4Y1; Q9H8D3; Q9ULE9;
DE   RecName: Full=Mitochondrial antiviral-signaling protein;
DE            Short=MAVS;
DE   AltName: Full=CARD adapter inducing interferon beta;
DE            Short=Cardif;
DE   AltName: Full=Interferon beta promoter stimulator protein 1;
DE            Short=IPS-1;
DE   AltName: Full=Putative NF-kappa-B-activating protein 031N;
DE   AltName: Full=Virus-induced-signaling adapter;
DE            Short=VISA;
GN   Name=MAVS; Synonyms=IPS1, KIAA1271, VISA;
DR   GO; GO:0050700; F:CARD domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0002218; P:activation of innate immune response; IMP:BHF-UCL.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IMP:BHF-UCL.
DR   GO; GO:0042742; P:defense response to bacterium; IMP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0071651; P:positive regulation of chemokine (C-C motif) ligand 5 production; IDA:BHF-UCL.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0071660; P:positive regulation of IP-10 production; IDA:BHF-UCL.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:1900063; P:regulation of peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0039529; P:RIG-I signaling pathway; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MAX_HUMAN               Reviewed;         160 AA.
AC   P61244; A6NH73; A8K265; A8K4G4; A8K824; P25912; P52163; Q14803;
AC   Q96CY8;
DE   RecName: Full=Protein max;
DE   AltName: Full=Class D basic helix-loop-helix protein 4;
DE            Short=bHLHd4;
DE   AltName: Full=Myc-associated factor X;
GN   Name=MAX; Synonyms=BHLHD4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MAZ_HUMAN               Reviewed;         477 AA.
AC   P56270; A8QJL9; C6G496; G5E927; Q15703; Q8NFN7; Q99443;
DE   RecName: Full=Myc-associated zinc finger protein;
DE            Short=MAZI;
DE   AltName: Full=Pur-1;
DE   AltName: Full=Purine-binding transcription factor;
DE   AltName: Full=Serum amyloid A-activating factor-1;
DE            Short=SAF-1;
DE   AltName: Full=Transcription factor Zif87;
DE   AltName: Full=ZF87;
DE   AltName: Full=Zinc finger protein 801;
GN   Name=MAZ; Synonyms=ZNF801;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MB12A_HUMAN             Reviewed;         273 AA.
AC   Q96EY5; Q96I18;
DE   RecName: Full=Multivesicular body subunit 12A;
DE   AltName: Full=CIN85/CD2AP family-binding protein;
DE   AltName: Full=ESCRT-I complex subunit MVB12A;
DE   AltName: Full=Protein FAM125A;
GN   Name=MVB12A; Synonyms=CFBP, FAM125A;
DR   GO; GO:0008289; F:lipid binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0043130; F:ubiquitin binding; IMP:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IC:UniProt.
//
ID   MB211_HUMAN             Reviewed;         359 AA.
AC   Q13394; Q6I9T5;
DE   RecName: Full=Protein mab-21-like 1;
GN   Name=MAB21L1; Synonyms=CAGR1; ORFNames=Nbla00126;
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   MB12B_HUMAN             Reviewed;         319 AA.
AC   Q9H7P6; Q8N6S7;
DE   RecName: Full=Multivesicular body subunit 12B;
DE   AltName: Full=ESCRT-I complex subunit MVB12B;
DE   AltName: Full=Protein FAM125B;
GN   Name=MVB12B; Synonyms=C9orf28, FAM125B;
DR   GO; GO:0008289; F:lipid binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IC:UniProt.
//
ID   MB212_HUMAN             Reviewed;         359 AA.
AC   Q9Y586; B3KP37; Q9HBA7;
DE   RecName: Full=Protein mab-21-like 2;
GN   Name=MAB21L2;
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0010172; P:embryonic body morphogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   MB213_HUMAN             Reviewed;         362 AA.
AC   Q8N8X9; Q5TDL7;
DE   RecName: Full=Protein mab-21-like 3;
GN   Name=MAB21L3; Synonyms=C1orf161;
//
ID   MB3L1_HUMAN             Reviewed;         194 AA.
AC   Q8WWY6; B5BUM6; Q2M291;
DE   RecName: Full=Methyl-CpG-binding domain protein 3-like 1;
DE            Short=MBD3-like protein 1;
GN   Name=MBD3L1; Synonyms=MBD3L;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MB3L2_HUMAN             Reviewed;         208 AA.
AC   Q8NHZ7;
DE   RecName: Full=Methyl-CpG-binding domain protein 3-like 2;
DE            Short=MBD3-like protein 2;
GN   Name=MBD3L2;
//
ID   MB3L3_HUMAN             Reviewed;         208 AA.
AC   A6NE82;
DE   RecName: Full=Putative methyl-CpG-binding domain protein 3-like 3;
DE            Short=MBD3-like protein 3;
GN   Name=MBD3L3;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MB3L4_HUMAN             Reviewed;         208 AA.
AC   A6NDZ8;
DE   RecName: Full=Putative methyl-CpG-binding domain protein 3-like 4;
DE            Short=MBD3-like protein 4;
GN   Name=MBD3L4;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MB3L5_HUMAN             Reviewed;         208 AA.
AC   A6NJ08;
DE   RecName: Full=Putative methyl-CpG-binding domain protein 3-like 5;
DE            Short=MBD3-like protein 5;
GN   Name=MBD3L5;
//
ID   MBB1A_HUMAN             Reviewed;        1328 AA.
AC   Q9BQG0; Q86VM3; Q9BW49; Q9P0V5; Q9UF99;
DE   RecName: Full=Myb-binding protein 1A;
GN   Name=MYBBP1A; Synonyms=P160;
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MBD2_HUMAN              Reviewed;         411 AA.
AC   Q9UBB5; O95242; Q9UIS8;
DE   RecName: Full=Methyl-CpG-binding domain protein 2;
DE   AltName: Full=Demethylase;
DE            Short=DMTase;
DE   AltName: Full=Methyl-CpG-binding protein MBD2;
GN   Name=MBD2;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003696; F:satellite DNA binding; TAS:ProtInc.
DR   GO; GO:0035197; F:siRNA binding; IEA:Ensembl.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MBD1_HUMAN              Reviewed;         605 AA.
AC   Q9UIS9; A4UTZ0; B4DXJ5; E9PEC5; K7ELI2; K7EQZ4; K7ESN0; O15248;
AC   O95241; Q7Z7B5; Q8N4W4; Q9UNZ6; Q9UNZ7; Q9UNZ8; Q9UNZ9;
DE   RecName: Full=Methyl-CpG-binding domain protein 1;
DE   AltName: Full=CXXC-type zinc finger protein 3;
DE   AltName: Full=Methyl-CpG-binding protein MBD1;
DE   AltName: Full=Protein containing methyl-CpG-binding domain 1;
GN   Name=MBD1; Synonyms=CXXC3, PCM1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008327; F:methyl-CpG binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MBD4_HUMAN              Reviewed;         580 AA.
AC   O95243; B4DZN2; D3DNC3; D3DNC4; E9PEE4; Q2MD36; Q7Z4T3; Q96F09;
DE   RecName: Full=Methyl-CpG-binding domain protein 4;
DE            EC=3.2.2.-;
DE   AltName: Full=Methyl-CpG-binding endonuclease 1;
DE   AltName: Full=Methyl-CpG-binding protein MBD4;
DE   AltName: Full=Mismatch-specific DNA N-glycosylase;
GN   Name=MBD4; Synonyms=MED1;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008263; F:pyrimidine-specific mismatch base pair DNA N-glycosylase activity; IDA:MGI.
DR   GO; GO:0003696; F:satellite DNA binding; TAS:ProtInc.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0045008; P:depyrimidination; TAS:Reactome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; TAS:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
//
ID   MBD5_HUMAN              Reviewed;        1494 AA.
AC   Q9P267; A5HMQ4; A7E2B1; Q53SR1; Q9NUV6;
DE   RecName: Full=Methyl-CpG-binding domain protein 5;
DE   AltName: Full=Methyl-CpG-binding protein MBD5;
GN   Name=MBD5; Synonyms=KIAA1461;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProt.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProt.
DR   GO; GO:0060399; P:positive regulation of growth hormone receptor signaling pathway; ISS:UniProt.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:UniProt.
DR   GO; GO:0044708; P:single-organism behavior; IMP:UniProt.
//
ID   MBD6_HUMAN              Reviewed;        1003 AA.
AC   Q96DN6; Q8N3M0; Q8NA81; Q96Q00;
DE   RecName: Full=Methyl-CpG-binding domain protein 6;
DE   AltName: Full=Methyl-CpG-binding protein MBD6;
GN   Name=MBD6; Synonyms=KIAA1887;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
//
ID   MBD3_HUMAN              Reviewed;         291 AA.
AC   O95983; A8K4B7; D6W5Z2; Q6PIL9; Q6PJZ9; Q86XF4;
DE   RecName: Full=Methyl-CpG-binding domain protein 3;
DE   AltName: Full=Methyl-CpG-binding protein MBD3;
GN   Name=MBD3;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0016573; P:histone acetylation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006346; P:methylation-dependent chromatin silencing; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009888; P:tissue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MBIP1_HUMAN             Reviewed;         344 AA.
AC   Q9NS73; Q86TZ2; Q96AS5; Q9BS93; Q9NZE1;
DE   RecName: Full=MAP3K12-binding inhibitory protein 1;
DE   AltName: Full=MAPK upstream kinase-binding inhibitory protein;
DE            Short=MUK-binding inhibitory protein;
GN   Name=MBIP; ORFNames=BM-015;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; TAS:ProtInc.
//
ID   MBL2_HUMAN              Reviewed;         248 AA.
AC   P11226; Q4VB12; Q4VB13; Q86SI4; Q96KE4; Q96TF7; Q96TF8; Q96TF9;
DE   RecName: Full=Mannose-binding protein C;
DE            Short=MBP-C;
DE   AltName: Full=Collectin-1;
DE   AltName: Full=MBP1;
DE   AltName: Full=Mannan-binding protein;
DE   AltName: Full=Mannose-binding lectin;
DE   Flags: Precursor;
GN   Name=MBL2; Synonyms=COLEC1, MBL;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005537; F:mannose binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; TAS:BHF-UCL.
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0001867; P:complement activation, lectin pathway; IPI:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:MGI.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0051873; P:killing by host of symbiont cells; IEA:Ensembl.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IDA:MGI.
DR   GO; GO:0008228; P:opsonization; TAS:BHF-UCL.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; NAS:UniProtKB.
//
ID   MBLC1_HUMAN             Reviewed;         266 AA.
AC   A4D2B0; Q8N5X8;
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein 1;
DE            EC=3.-.-.-;
GN   Name=MBLAC1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   MBLC2_HUMAN             Reviewed;         279 AA.
AC   Q68D91; D6RJI1; Q8IY16; Q8N8D8;
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein 2;
DE            EC=3.-.-.-;
GN   Name=MBLAC2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   MBNL1_HUMAN             Reviewed;         388 AA.
AC   Q9NR56; E9PBW7; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3;
DE   RecName: Full=Muscleblind-like protein 1;
DE   AltName: Full=Triplet-expansion RNA-binding protein;
GN   Name=MBNL1; Synonyms=EXP, KIAA0428, MBNL;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:Ensembl.
DR   GO; GO:0045445; P:myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IDA:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
//
ID   MBNL2_HUMAN             Reviewed;         373 AA.
AC   Q5VZF2; Q3SXY5; Q58F19; Q8NEV3; Q8TD82;
DE   RecName: Full=Muscleblind-like protein 2;
DE   AltName: Full=Muscleblind-like protein 1;
DE   AltName: Full=Muscleblind-like protein-like;
DE   AltName: Full=Muscleblind-like protein-like 39;
GN   Name=MBNL2; Synonyms=MBLL, MBLL39, MLP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   MBNL3_HUMAN             Reviewed;         354 AA.
AC   Q9NUK0; Q5JXN8; Q5JXN9; Q5JXP4; Q6UDQ1; Q8IUR4; Q8TAD9; Q8TAF4;
AC   Q9H0Z7; Q9UF37;
DE   RecName: Full=Muscleblind-like protein 3;
DE   AltName: Full=Cys3His CCG1-required protein;
DE   AltName: Full=Muscleblind-like X-linked protein;
DE   AltName: Full=Protein HCHCR;
GN   Name=MBNL3; Synonyms=CHCR, MBLX39, MBXL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   MBOA1_HUMAN             Reviewed;         495 AA.
AC   Q6ZNC8; A9EDQ5; B4DL59; B4E3J4; Q86XC2; Q8N9R5;
DE   RecName: Full=Lysophospholipid acyltransferase 1;
DE            Short=LPLAT 1;
DE            EC=2.3.1.-;
DE   AltName: Full=1-acylglycerophosphoserine O-acyltransferase;
DE            EC=2.3.1.n6;
DE   AltName: Full=Lysophosphatidylserine acyltransferase;
DE            Short=LPSAT;
DE            Short=Lyso-PS acyltransferase;
DE   AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 1;
DE            Short=O-acyltransferase domain-containing protein 1;
GN   Name=MBOAT1; Synonyms=OACT1;
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MBOA2_HUMAN             Reviewed;         520 AA.
AC   Q6ZWT7; A9EDR2; Q8NCE7; Q96KY4;
DE   RecName: Full=Lysophospholipid acyltransferase 2;
DE            Short=LPLAT 2;
DE            EC=2.3.1.-;
DE   AltName: Full=1-acylglycerophosphate O-acyltransferase;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerophosphoethanolamine O-acyltransferase;
DE            EC=2.3.1.n7;
DE   AltName: Full=Lysophosphatidic acid acyltransferase;
DE            Short=LPAAT;
DE            Short=Lyso-PA acyltransferase;
DE   AltName: Full=Lysophosphatidylethanolamine acyltransferase;
DE            Short=LPEAT;
DE            Short=Lyso-PE acyltransferase;
DE   AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 2;
DE            Short=O-acyltransferase domain-containing protein 2;
GN   Name=MBOAT2; Synonyms=OACT2;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MBOA5_HUMAN             Reviewed;         487 AA.
AC   Q6P1A2; B2RDH0; B7Z3N3; Q7KZS1; Q92980; Q9BW40;
DE   RecName: Full=Lysophospholipid acyltransferase 5;
DE            Short=LPLAT 5;
DE            EC=2.3.1.-;
DE   AltName: Full=1-acylglycerophosphocholine O-acyltransferase;
DE            EC=2.3.1.23;
DE   AltName: Full=1-acylglycerophosphoserine O-acyltransferase;
DE            EC=2.3.1.n6;
DE   AltName: Full=Lysophosphatidylcholine acyltransferase;
DE            Short=LPCAT;
DE            Short=Lyso-PC acyltransferase;
DE   AltName: Full=Lysophosphatidylcholine acyltransferase 3;
DE            Short=Lyso-PC acyltransferase 3;
DE   AltName: Full=Lysophosphatidylserine acyltransferase;
DE            Short=LPSAT;
DE            Short=Lyso-PS acyltransferase;
DE   AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 5;
DE            Short=O-acyltransferase domain-containing protein 5;
GN   Name=LPCAT3; Synonyms=MBOAT5, OACT5;
DR   GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IMP:MGI.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0097006; P:regulation of plasma lipoprotein particle levels; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MBOA4_HUMAN             Reviewed;         435 AA.
AC   Q96T53; B1Q003;
DE   RecName: Full=Ghrelin O-acyltransferase;
DE            EC=2.3.1.-;
DE   AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 4;
DE            Short=O-acyltransferase domain-containing protein 4;
GN   Name=MBOAT4; Synonyms=GOAT, OACT4; ORFNames=FKSG89;
DR   GO; GO:0016412; F:serine O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0018191; P:peptidyl-serine octanoylation; IDA:UniProtKB.
//
ID   MBOA7_HUMAN             Reviewed;         472 AA.
AC   Q96N66; A9C4B6; B0V3I5; B4DQ87; Q05DF0; Q7L5N2; Q99908; Q9BPV2;
AC   Q9BRE9;
DE   RecName: Full=Lysophospholipid acyltransferase 7;
DE            Short=LPLAT 7;
DE            EC=2.3.1.-;
DE   AltName: Full=1-acylglycerophosphatidylinositol O-acyltransferase;
DE            EC=2.3.1.n4;
DE   AltName: Full=Bladder and breast carcinoma-overexpressed gene 1 protein;
DE   AltName: Full=Leukocyte receptor cluster member 4;
DE   AltName: Full=Lysophosphatidylinositol acyltransferase;
DE            Short=LPIAT;
DE            Short=Lyso-PI acyltransferase;
DE   AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 7;
DE            Short=O-acyltransferase domain-containing protein 7;
DE            Short=h-mboa-7;
GN   Name=MBOAT7; Synonyms=BB1, LENG4, OACT7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
//
ID   MBPHL_HUMAN             Reviewed;         354 AA.
AC   A2RUH7; Q5T2Z7;
DE   RecName: Full=Myosin-binding protein H-like;
GN   Name=MYBPHL;
//
ID   MBP_HUMAN               Reviewed;         304 AA.
AC   P02686; A4FU54; A6NI84; A8MY86; A8MYL4; B3KY66; B7ZKS2; B7ZKS4;
AC   Q15337; Q15338; Q15339; Q15340; Q59GX3; Q65ZS4; Q6AI64; Q6FH37;
AC   Q6FI04; Q6PK23;
DE   RecName: Full=Myelin basic protein;
DE            Short=MBP;
DE   AltName: Full=Myelin A1 protein;
DE   AltName: Full=Myelin membrane encephalitogenic protein;
GN   Name=MBP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019911; F:structural constituent of myelin sheath; IEA:Ensembl.
DR   GO; GO:0008366; P:axon ensheathment; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   MBRL_HUMAN              Reviewed;         620 AA.
AC   Q4ZIN3; O60392; Q8NF79; Q96H30;
DE   RecName: Full=Membralin;
DE   AltName: Full=Transmembrane protein 259;
GN   Name=TMEM259; Synonyms=C19orf6;
//
ID   MBTD1_HUMAN             Reviewed;         628 AA.
AC   Q05BQ5; Q6ZVU7; Q9NXU1;
DE   RecName: Full=MBT domain-containing protein 1;
GN   Name=MBTD1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MBTP1_HUMAN             Reviewed;        1052 AA.
AC   Q14703; A8K6V8; Q24JQ2; Q9UF67;
DE   RecName: Full=Membrane-bound transcription factor site-1 protease;
DE            EC=3.4.21.112;
DE   AltName: Full=Endopeptidase S1P;
DE   AltName: Full=Subtilisin/kexin-isozyme 1;
DE            Short=SKI-1;
DE   Flags: Precursor;
GN   Name=MBTPS1; Synonyms=KIAA0091, S1P, SKI1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; IBA:RefGenome.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
DR   GO; GO:0042990; P:regulation of transcription factor import into nucleus; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MBTP2_HUMAN             Reviewed;         519 AA.
AC   O43462; Q9UM70; Q9UMD3;
DE   RecName: Full=Membrane-bound transcription factor site-2 protease;
DE            EC=3.4.24.85;
DE   AltName: Full=Endopeptidase S2P;
DE   AltName: Full=Sterol regulatory element-binding proteins intramembrane protease;
DE            Short=SREBPs intramembrane protease;
GN   Name=MBTPS2; Synonyms=S2P;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MC3R_HUMAN              Reviewed;         323 AA.
AC   P41968; Q4KN27; Q9H517;
DE   RecName: Full=Melanocortin receptor 3;
DE            Short=MC3-R;
GN   Name=MC3R;
DR   GuidetoPHARMACOLOGY; 284; -.
DR   GO; GO:0004977; F:melanocortin receptor activity; TAS:ProtInc.
DR   GO; GO:0004980; F:melanocyte-stimulating hormone receptor activity; IPI:BHF-UCL.
DR   GO; GO:0042923; F:neuropeptide binding; IPI:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0042309; P:homoiothermy; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0055078; P:sodium ion homeostasis; IEA:Ensembl.
//
ID   MC4R_HUMAN              Reviewed;         332 AA.
AC   P32245; B2RAC3; Q16317; Q3MIJ6;
DE   RecName: Full=Melanocortin receptor 4;
DE            Short=MC4-R;
GN   Name=MC4R;
DR   GuidetoPHARMACOLOGY; 285; -.
DR   GO; GO:0004977; F:melanocortin receptor activity; TAS:ProtInc.
DR   GO; GO:0004980; F:melanocyte-stimulating hormone receptor activity; IPI:BHF-UCL.
DR   GO; GO:0042923; F:neuropeptide binding; IPI:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0002024; P:diet induced thermogenesis; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IMP:HGNC.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:2000821; P:regulation of grooming behavior; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
//
ID   MC5R_HUMAN              Reviewed;         325 AA.
AC   P33032; B0YJ34; Q502V1;
DE   RecName: Full=Melanocortin receptor 5;
DE            Short=MC5-R;
DE   AltName: Full=MC-2;
GN   Name=MC5R;
DR   GuidetoPHARMACOLOGY; 286; -.
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0004977; F:melanocortin receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
//
ID   MCA3_HUMAN              Reviewed;         174 AA.
AC   O43324; C9JLK5; Q5THS2;
DE   RecName: Full=Eukaryotic translation elongation factor 1 epsilon-1;
DE   AltName: Full=Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3;
DE   AltName: Full=Elongation factor p18;
DE   AltName: Full=Multisynthase complex auxiliary component p18;
GN   Name=EEF1E1; Synonyms=AIMP3, P18;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   MCAF1_HUMAN             Reviewed;        1270 AA.
AC   Q6VMQ6; Q4G0T9; Q6P3T3; Q86XW5; Q9NVJ9; Q9NWC2; Q9Y4X8;
DE   RecName: Full=Activating transcription factor 7-interacting protein 1;
DE   AltName: Full=ATF-interacting protein;
DE            Short=ATF-IP;
DE   AltName: Full=ATF7-interacting protein;
DE   AltName: Full=ATFa-associated modulator;
DE            Short=hAM;
DE   AltName: Full=MBD1-containing chromatin-associated factor 1;
DE   AltName: Full=P621;
GN   Name=ATF7IP; Synonyms=MCAF, MCAF1;
DR   GO; GO:0016887; F:ATPase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0006306; P:DNA methylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045898; P:regulation of RNA polymerase II transcriptional preinitiation complex assembly; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MCAF2_HUMAN             Reviewed;         682 AA.
AC   Q5U623; B2RNR2; Q53EZ7; Q658U2; Q6IS97; Q8N9X8; Q9H9L6;
DE   RecName: Full=Activating transcription factor 7-interacting protein 2;
DE            Short=ATF7-interacting protein 2;
DE   AltName: Full=MBD1-containing chromatin-associated factor 2;
GN   Name=ATF7IP2; Synonyms=MCAF2;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MCATL_HUMAN             Reviewed;         303 AA.
AC   Q8N8R3; Q541V0;
DE   RecName: Full=Mitochondrial carnitine/acylcarnitine carrier protein CACL;
DE   AltName: Full=Carnitine/acylcarnitine translocase-like;
DE            Short=CACT-like;
DE   AltName: Full=Mitochondrial ornithine transporter 3;
DE   AltName: Full=Solute carrier family 25 member 29;
GN   Name=SLC25A29; Synonyms=C14orf69, ORNT3;
DR   GO; GO:0015227; F:acyl carnitine transmembrane transporter activity; IEA:Ensembl.
//
ID   MCAT_HUMAN              Reviewed;         301 AA.
AC   O43772; B2R7F4; Q9UIQ2;
DE   RecName: Full=Mitochondrial carnitine/acylcarnitine carrier protein;
DE   AltName: Full=Carnitine/acylcarnitine translocase;
DE            Short=CAC;
DE   AltName: Full=Solute carrier family 25 member 20;
GN   Name=SLC25A20; Synonyms=CAC, CACT;
DR   GO; GO:0006853; P:carnitine shuttle; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MCCA_HUMAN              Reviewed;         725 AA.
AC   Q96RQ3; Q59ES4; Q9H959; Q9NS97;
DE   RecName: Full=Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial;
DE            Short=MCCase subunit alpha;
DE            EC=6.4.1.4;
DE   AltName: Full=3-methylcrotonyl-CoA carboxylase 1;
DE   AltName: Full=3-methylcrotonyl-CoA carboxylase biotin-containing subunit;
DE   AltName: Full=3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha;
DE   Flags: Precursor;
GN   Name=MCCC1; Synonyms=MCCA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0009374; F:biotin binding; NAS:UniProtKB.
DR   GO; GO:0004075; F:biotin carboxylase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006768; P:biotin metabolic process; NAS:UniProtKB.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006552; P:leucine catabolic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MCCB_HUMAN              Reviewed;         563 AA.
AC   Q9HCC0; A6NIY9; Q96C27; Q9Y4L7;
DE   RecName: Full=Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial;
DE            Short=MCCase subunit beta;
DE            EC=6.4.1.4;
DE   AltName: Full=3-methylcrotonyl-CoA carboxylase 2;
DE   AltName: Full=3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit;
DE   AltName: Full=3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta;
DE   Flags: Precursor;
GN   Name=MCCC2; Synonyms=MCCB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0015936; P:coenzyme A metabolic process; IEA:Ensembl.
DR   GO; GO:0006552; P:leucine catabolic process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MCCD1_HUMAN             Reviewed;         119 AA.
AC   P59942; A2AB29; A2RUP7; B0UZB2; Q7RTY2;
DE   RecName: Full=Mitochondrial coiled-coil domain protein 1;
DE   Flags: Precursor;
GN   Name=MCCD1;
//
ID   MCE1_HUMAN              Reviewed;         597 AA.
AC   O60942; E1P513; E1P514; O43483; O60257; O60351; Q5TCW8; Q8WUM8;
DE   RecName: Full=mRNA-capping enzyme;
DE   AltName: Full=HCAP1;
DE   AltName: Full=HCE;
DE   Includes:
DE     RecName: Full=Polynucleotide 5'-triphosphatase;
DE              EC=3.1.3.33;
DE     AltName: Full=mRNA 5'-triphosphatase;
DE              Short=TPase;
DE   Includes:
DE     RecName: Full=mRNA guanylyltransferase;
DE              EC=2.7.7.50;
DE     AltName: Full=GTP--RNA guanylyltransferase;
DE              Short=GTase;
GN   Name=RNGTT; Synonyms=CAP1A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004484; F:mRNA guanylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004651; F:polynucleotide 5'-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008192; F:RNA guanylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0050355; F:triphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006396; P:RNA processing; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   MCEE_HUMAN              Reviewed;         176 AA.
AC   Q96PE7; Q53TP1; Q8WW63;
DE   RecName: Full=Methylmalonyl-CoA epimerase, mitochondrial;
DE            EC=5.1.99.1;
DE   AltName: Full=DL-methylmalonyl-CoA racemase;
DE   Flags: Precursor;
GN   Name=MCEE;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004493; F:methylmalonyl-CoA epimerase activity; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0046491; P:L-methylmalonyl-CoA metabolic process; IDA:UniProtKB.
DR   GO; GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MCEM1_HUMAN             Reviewed;         187 AA.
AC   Q8IX19; Q8IX20;
DE   RecName: Full=Mast cell-expressed membrane protein 1;
GN   Name=MCEMP1; Synonyms=C19orf59;
//
ID   MCES_HUMAN              Reviewed;         476 AA.
AC   O43148; B0YJ90; D3DUJ5; O94996; Q9UIJ9;
DE   RecName: Full=mRNA cap guanine-N7 methyltransferase;
DE            EC=2.1.1.56;
DE   AltName: Full=RG7MT1;
DE   AltName: Full=mRNA (guanine-N(7)-)-methyltransferase;
DE   AltName: Full=mRNA cap methyltransferase;
DE            Short=hCMT1;
DE            Short=hMet;
DE            Short=hcm1p;
GN   Name=RNMT; Synonyms=KIAA0398;
DR   GO; GO:0004482; F:mRNA (guanine-N7-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IMP:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0036265; P:RNA (guanine-N7)-methylation; IDA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   MCF2L_HUMAN             Reviewed;        1137 AA.
AC   O15068; A2A2X1; A2A2X2; A2A3G6; A2A3G8; B4DHD6; B4DIL6; E9PDN8;
AC   Q5JU56; Q5VXT1; Q6ZWD4; Q765G8; Q765G9; Q8N679;
DE   RecName: Full=Guanine nucleotide exchange factor DBS;
DE   AltName: Full=DBL's big sister;
DE   AltName: Full=MCF2-transforming sequence-like protein;
GN   Name=MCF2L; Synonyms=KIAA0362;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   MCF2_HUMAN              Reviewed;         925 AA.
AC   P10911; B7Z3Y5; B7Z869; B7ZAV1; E9PH77; F5H091; P14919; Q5JYJ2;
AC   Q5JYJ3; Q5JYJ4; Q8IUF3; Q8IUF4; Q9UJB3;
DE   RecName: Full=Proto-oncogene DBL;
DE   AltName: Full=Proto-oncogene MCF-2;
DE   Contains:
DE     RecName: Full=MCF2-transforming protein;
DE   Contains:
DE     RecName: Full=DBL-transforming protein;
GN   Name=MCF2; Synonyms=DBL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   MCFD2_HUMAN             Reviewed;         146 AA.
AC   Q8NI22; A8K7W2; D6W5A9; E9PD95; Q53SS3; Q68D61; Q8N3M5;
DE   RecName: Full=Multiple coagulation factor deficiency protein 2;
DE   AltName: Full=Neural stem cell-derived neuronal survival protein;
DE   Flags: Precursor;
GN   Name=MCFD2; Synonyms=SDNSF;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   MCHL2_HUMAN             Reviewed;          86 AA.
AC   Q9BQD1;
DE   RecName: Full=Putative pro-MCH-like protein 2;
DE   AltName: Full=Pro-melanin-concentrating hormone-like protein 2;
GN   Name=PMCHL2;
DR   GO; GO:0007268; P:synaptic transmission; IEA:InterPro.
//
ID   MCHR1_HUMAN             Reviewed;         422 AA.
AC   Q99705; B2RBX6; Q5R3J1; Q96S47; Q9BV08;
DE   RecName: Full=Melanin-concentrating hormone receptor 1;
DE            Short=MCH receptor 1;
DE            Short=MCH-R1;
DE            Short=MCHR-1;
DE   AltName: Full=G-protein coupled receptor 24;
DE   AltName: Full=MCH-1R;
DE            Short=MCH1R;
DE            Short=MCHR;
DE   AltName: Full=SLC-1;
DE   AltName: Full=Somatostatin receptor-like protein;
GN   Name=MCHR1; Synonyms=GPR24, SLC1;
DR   GuidetoPHARMACOLOGY; 280; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0030273; F:melanin-concentrating hormone receptor activity; IEA:Ensembl.
DR   GO; GO:0008188; F:neuropeptide receptor activity; TAS:ProtInc.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
//
ID   MCHL1_HUMAN             Reviewed;          86 AA.
AC   Q16048; Q9BQ10;
DE   RecName: Full=Putative pro-MCH-like protein 1;
DE   AltName: Full=Pro-MCH variant;
DE   AltName: Full=Pro-melanin-concentrating hormone-like protein 1;
GN   Name=PMCHL1;
DR   GO; GO:0007268; P:synaptic transmission; IEA:InterPro.
//
ID   MCHR2_HUMAN             Reviewed;         340 AA.
AC   Q969V1; B3KVW4; E1P5D7; Q5VTV7; Q6Q377; Q9BXA8;
DE   RecName: Full=Melanin-concentrating hormone receptor 2;
DE            Short=MCH receptor 2;
DE            Short=MCH-R2;
DE            Short=MCHR-2;
DE   AltName: Full=G-protein coupled receptor 145;
DE   AltName: Full=GPRv17;
DE   AltName: Full=MCH-2R;
DE            Short=MCH2;
DE            Short=MCH2R;
GN   Name=MCHR2; Synonyms=GPR145, SLT;
DR   GuidetoPHARMACOLOGY; 281; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MCH_HUMAN               Reviewed;         165 AA.
AC   P20382; Q16044; Q8WVG0;
DE   RecName: Full=Pro-MCH;
DE   Contains:
DE     RecName: Full=Neuropeptide-glycine-glutamic acid;
DE              Short=NGE;
DE              Short=Neuropeptide G-E;
DE   Contains:
DE     RecName: Full=Neuropeptide-glutamic acid-isoleucine;
DE              Short=NEI;
DE              Short=Neuropeptide E-I;
DE   Contains:
DE     RecName: Full=Melanin-concentrating hormone;
DE              Short=MCH;
DE   Flags: Precursor;
GN   Name=PMCH; Synonyms=MCH;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007631; P:feeding behavior; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; IEA:InterPro.
//
ID   MCIN_HUMAN              Reviewed;         385 AA.
AC   D6RGH6; C9JGY3; D6R920; F8KGQ8;
DE   RecName: Full=Multicilin;
DE   AltName: Full=Multiciliate differentiation and DNA synthesis-associated cell cycle protein;
DE   AltName: Full=Protein Idas;
GN   Name=MCIDAS; Synonyms=IDAS, MCI, MCIN;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MCL1_HUMAN              Reviewed;         350 AA.
AC   Q07820; B2R6B2; D3DV03; D3DV04; Q9HD91; Q9NRQ3; Q9NRQ4; Q9UHR7;
AC   Q9UHR8; Q9UHR9; Q9UNJ1;
DE   RecName: Full=Induced myeloid leukemia cell differentiation protein Mcl-1;
DE   AltName: Full=Bcl-2-like protein 3;
DE            Short=Bcl2-L-3;
DE   AltName: Full=Bcl-2-related protein EAT/mcl1;
DE   AltName: Full=mcl1/EAT;
GN   Name=MCL1; Synonyms=BCL2L3;
DR   GO; GO:0051434; F:BH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015266; F:protein channel activity; TAS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0001709; P:cell fate determination; NAS:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; NAS:UniProtKB.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:1900118; P:negative regulation of execution phase of apoptosis; TAS:UniProtKB.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IBA:RefGenome.
DR   GO; GO:0071806; P:protein transmembrane transport; TAS:GOC.
DR   GO; GO:2001020; P:regulation of response to DNA damage stimulus; IMP:MGI.
DR   GO; GO:0034097; P:response to cytokine; IDA:MGI.
//
ID   MCLN1_HUMAN             Reviewed;         580 AA.
AC   Q9GZU1; D6W647; Q7Z4F7; Q9H292; Q9H4B3; Q9H4B5;
DE   RecName: Full=Mucolipin-1;
DE   AltName: Full=MG-2;
DE   AltName: Full=Mucolipidin;
GN   Name=MCOLN1; Synonyms=ML4; ORFNames=MSTP080;
DR   GuidetoPHARMACOLOGY; 501; -.
DR   GO; GO:0005261; F:cation channel activity; NAS:UniProtKB.
DR   GO; GO:0072345; F:NAADP-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006812; P:cation transport; NAS:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MCLN2_HUMAN             Reviewed;         566 AA.
AC   Q8IZK6; A6NI99; Q2M3I6; Q5TAG5; Q8N9R3;
DE   RecName: Full=Mucolipin-2;
GN   Name=MCOLN2;
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MCLN3_HUMAN             Reviewed;         553 AA.
AC   Q8TDD5; Q5T4H5; Q5T4H6; Q9NV09;
DE   RecName: Full=Mucolipin-3;
GN   Name=MCOLN3;
DR   GuidetoPHARMACOLOGY; 503; -.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MCM10_HUMAN             Reviewed;         875 AA.
AC   Q7L590; A8K9I6; B7ZKZ8; Q3MIR3; Q7LD55; Q96GX4; Q96NB6; Q9H0D7;
AC   Q9H3P9; Q9P177;
DE   RecName: Full=Protein MCM10 homolog;
DE            Short=HsMCM10;
GN   Name=MCM10; ORFNames=PRO2249;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCM2_HUMAN              Reviewed;         904 AA.
AC   P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7;
DE   RecName: Full=DNA replication licensing factor MCM2;
DE            EC=3.6.4.12;
DE   AltName: Full=Minichromosome maintenance protein 2 homolog;
DE   AltName: Full=Nuclear protein BM28;
GN   Name=MCM2; Synonyms=BM28, CCNL1, CDCL1, KIAA0030;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; IMP:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:Ensembl.
//
ID   MCM3_HUMAN              Reviewed;         808 AA.
AC   P25205; Q92660; Q9BTR3; Q9NUE7;
DE   RecName: Full=DNA replication licensing factor MCM3;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA polymerase alpha holoenzyme-associated protein P1;
DE   AltName: Full=P1-MCM3;
DE   AltName: Full=RLF subunit beta;
DE   AltName: Full=p102;
GN   Name=MCM3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCM4_HUMAN              Reviewed;         863 AA.
AC   P33991; Q8NEH1; Q99658;
DE   RecName: Full=DNA replication licensing factor MCM4;
DE            EC=3.6.4.12;
DE   AltName: Full=CDC21 homolog;
DE   AltName: Full=P1-CDC21;
GN   Name=MCM4; Synonyms=CDC21;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCM5_HUMAN              Reviewed;         734 AA.
AC   P33992; O60785; Q14578; Q9BTJ4; Q9BWL8;
DE   RecName: Full=DNA replication licensing factor MCM5;
DE            EC=3.6.4.12;
DE   AltName: Full=CDC46 homolog;
DE   AltName: Full=P1-CDC46;
GN   Name=MCM5; Synonyms=CDC46;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCM6_HUMAN              Reviewed;         821 AA.
AC   Q14566; B2R6H2; Q13504; Q99859;
DE   RecName: Full=DNA replication licensing factor MCM6;
DE            EC=3.6.4.12;
DE   AltName: Full=p105MCM;
GN   Name=MCM6;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCM7_HUMAN              Reviewed;         719 AA.
AC   P33993; A4D2A1; A4D2A2; E9PGN9; Q15076; Q96D34; Q96GL1;
DE   RecName: Full=DNA replication licensing factor MCM7;
DE            EC=3.6.4.12;
DE   AltName: Full=CDC47 homolog;
DE   AltName: Full=P1.1-MCM3;
GN   Name=MCM7; Synonyms=CDC47, MCM2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   MCM8_HUMAN              Reviewed;         840 AA.
AC   Q9UJA3; B2RBG7; D3DW08; E7EQU7; Q495R4; Q495R6; Q495R7; Q86US4;
AC   Q969I5;
DE   RecName: Full=DNA helicase MCM8;
DE            EC=3.6.4.12;
DE   AltName: Full=Minichromosome maintenance 8;
GN   Name=MCM8; Synonyms=C20orf154;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0007292; P:female gamete generation; ISS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048232; P:male gamete generation; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCM9_HUMAN              Reviewed;        1143 AA.
AC   Q9NXL9; B4DR30; B9DI77; Q2KHJ0; Q8N5S5; Q9HCV5;
DE   RecName: Full=DNA helicase MCM9;
DE            Short=hMCM9;
DE            EC=3.6.4.12;
DE   AltName: Full=Mini-chromosome maintenance deficient domain-containing protein 1;
DE   AltName: Full=Minichromosome maintenance 9;
GN   Name=MCM9; Synonyms=C6orf61, MCMDC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:0007292; P:female gamete generation; ISS:UniProtKB.
//
ID   MCMBP_HUMAN             Reviewed;         642 AA.
AC   Q9BTE3; B3KSP7; Q6IA56; Q9BVT9; Q9H916;
DE   RecName: Full=Mini-chromosome maintenance complex-binding protein;
DE            Short=MCM-BP;
DE            Short=MCM-binding protein;
GN   Name=MCMBP; Synonyms=C10orf119;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000084; P:mitotic S phase; IMP:UniProtKB.
DR   GO; GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.
//
ID   MCMD2_HUMAN             Reviewed;         681 AA.
AC   Q4G0Z9; B4DYZ3; B4DZM4; B4E293; Q6P533; Q7Z3P4;
DE   RecName: Full=MCM domain-containing protein 2;
GN   Name=MCMDC2; Synonyms=C8orf45;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
//
ID   MCP1_HUMAN              Reviewed;         290 AA.
AC   P0CW71;
DE   RecName: Full=Putative metaphase chromosome protein 1;
DE   AltName: Full=Metaphase chromosome protein 30;
GN   Name=HSMCR30; Synonyms=MCP1, MCP30;
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   MCPH1_HUMAN             Reviewed;         835 AA.
AC   Q8NEM0; B4DWW2; E9PGU5; E9PH63; Q66GU1; Q9H9C7;
DE   RecName: Full=Microcephalin;
GN   Name=MCPH1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MCP_HUMAN               Reviewed;         392 AA.
AC   P15529; A0T1T0; A0T1T1; A0T1T2; Q15429; Q53GV9; Q5HY94; Q5VWS6;
AC   Q5VWS7; Q5VWS8; Q5VWS9; Q5VWT0; Q5VWT1; Q5VWT2; Q6N0A1; Q7Z3R5;
AC   Q9NNW2; Q9NNW3; Q9NNW4; Q9UCJ4;
DE   RecName: Full=Membrane cofactor protein;
DE   AltName: Full=TLX;
DE   AltName: Full=Trophoblast leukocyte common antigen;
DE   AltName: CD_antigen=CD46;
DE   Flags: Precursor;
GN   Name=CD46; Synonyms=MCP, MIC10;
DR   GO; GO:0045296; F:cadherin binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0002250; P:adaptive immune response; IC:UniProt.
DR   GO; GO:0006958; P:complement activation, classical pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032613; P:interleukin-10 production; IDA:UniProt.
DR   GO; GO:0045916; P:negative regulation of complement activation; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProt.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProt.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IDA:UniProt.
DR   GO; GO:0043382; P:positive regulation of memory T cell differentiation; IDA:UniProt.
DR   GO; GO:0045591; P:positive regulation of regulatory T cell differentiation; IDA:UniProt.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:UniProt.
DR   GO; GO:0071636; P:positive regulation of transforming growth factor beta production; IDA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IEA:Ensembl.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; IDA:UniProt.
DR   GO; GO:0035581; P:sequestering of extracellular ligand from receptor; IDA:UniProt.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   GO; GO:0002456; P:T cell mediated immunity; IMP:UniProt.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MCRS1_HUMAN             Reviewed;         462 AA.
AC   Q96EZ8; O14742; O75497; Q6VN53; Q7Z372;
DE   RecName: Full=Microspherule protein 1;
DE   AltName: Full=58 kDa microspherule protein;
DE   AltName: Full=Cell cycle-regulated factor p78;
DE   AltName: Full=INO80 complex subunit J;
DE   AltName: Full=MCRS2;
GN   Name=MCRS1; Synonyms=INO80Q, MSP58;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MCR_HUMAN               Reviewed;         984 AA.
AC   P08235; B0ZBF5; B0ZBF7; Q2NKL1; Q96KQ8; Q96KQ9;
DE   RecName: Full=Mineralocorticoid receptor;
DE            Short=MR;
DE   AltName: Full=Nuclear receptor subfamily 3 group C member 2;
GN   Name=NR3C2; Synonyms=MCR, MLR;
DR   GuidetoPHARMACOLOGY; 626; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MCSP_HUMAN              Reviewed;         116 AA.
AC   P49901; Q96A42;
DE   RecName: Full=Sperm mitochondrial-associated cysteine-rich protein;
GN   Name=SMCP; Synonyms=MCS, MCSP;
DR   GO; GO:0007341; P:penetration of zona pellucida; ISS:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; ISS:UniProtKB.
//
ID   MCTP2_HUMAN             Reviewed;         878 AA.
AC   Q6DN12; A2RRC2; C6G483; C6G484; Q49AB0; Q8TAX2; Q9NUS2; Q9NUW7;
DE   RecName: Full=Multiple C2 and transmembrane domain-containing protein 2;
GN   Name=MCTP2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:HGNC.
DR   GO; GO:0019722; P:calcium-mediated signaling; NAS:HGNC.
//
ID   MCTP1_HUMAN             Reviewed;         999 AA.
AC   Q6DN14; Q6DN13; Q8N2W1; Q8NBA2; Q96LX0; Q9H6E8;
DE   RecName: Full=Multiple C2 and transmembrane domain-containing protein 1;
GN   Name=MCTP1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:HGNC.
DR   GO; GO:0019722; P:calcium-mediated signaling; NAS:HGNC.
//
ID   MCTS1_HUMAN             Reviewed;         181 AA.
AC   Q9ULC4; B4DGY2; Q502X6;
DE   RecName: Full=Malignant T-cell-amplified sequence 1;
DE            Short=MCT-1;
DE   AltName: Full=Multiple copies T-cell malignancies;
GN   Name=MCTS1; Synonyms=MCT1;
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MCUR1_HUMAN             Reviewed;         359 AA.
AC   Q96AQ8; Q96JS7; Q9H7F8;
DE   RecName: Full=Mitochondrial calcium uniporter regulator 1;
DE   AltName: Full=Coiled-coil domain-containing protein 90A, mitochondrial;
GN   Name=MCUR1; Synonyms=C6orf79, CCDC90A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070509; P:calcium ion import; IMP:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IMP:UniProtKB.
//
ID   MCUB_HUMAN              Reviewed;         336 AA.
AC   Q9NWR8; A8K4Y3; Q6IAC1;
DE   RecName: Full=Mitochondrial calcium uniporter regulatory subunit MCUb;
DE            Short=MCUb;
DE   AltName: Full=Coiled-coil domain-containing protein 109B;
DE   AltName: Full=Essential MCU regulator;
DE            Short=EMRE;
GN   Name=CCDC109B; Synonyms=MCUB;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0051560; P:mitochondrial calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; ISS:UniProtKB.
//
ID   MCU_HUMAN               Reviewed;         351 AA.
AC   Q8NE86; B2RDF3; B3KXV7; Q96FL3;
DE   RecName: Full=Calcium uniporter protein, mitochondrial;
DE   AltName: Full=Coiled-coil domain-containing protein 109A;
GN   Name=MCU; Synonyms=C10orf42, CCDC109A;
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015292; F:uniporter activity; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0035786; P:protein complex oligomerization; IDA:UniProtKB.
//
ID   MD12L_HUMAN             Reviewed;        2145 AA.
AC   Q86YW9; Q96PC7; Q96PC8; Q9H9M5; Q9HCD7; Q9UI69;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 12-like protein;
DE   AltName: Full=Mediator complex subunit 12-like protein;
DE   AltName: Full=Thyroid hormone receptor-associated-like protein;
DE   AltName: Full=Trinucleotide repeat-containing gene 11 protein-like;
GN   Name=MED12L; Synonyms=KIAA1635, TNRC11L, TRALP, TRALPUSH;
GN   ORFNames=PRO0314;
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MD13L_HUMAN             Reviewed;        2210 AA.
AC   Q71F56; A1L469; Q68DN4; Q9H8C0; Q9NSY9; Q9UFD8; Q9UPX5;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 13-like;
DE   AltName: Full=Mediator complex subunit 13-like;
DE   AltName: Full=Thyroid hormone receptor-associated protein 2;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 240 kDa component-like;
GN   Name=MED13L; Synonyms=KIAA1025, PROSIT240, THRAP2, TRAP240L;
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MD1L1_HUMAN             Reviewed;         718 AA.
AC   Q9Y6D9; Q13312; Q75MI0; Q86UM4; Q9UNH0;
DE   RecName: Full=Mitotic spindle assembly checkpoint protein MAD1;
DE   AltName: Full=Mitotic arrest deficient 1-like protein 1;
DE            Short=MAD1-like protein 1;
DE   AltName: Full=Mitotic checkpoint MAD1 protein homolog;
DE            Short=HsMAD1;
DE            Short=hMAD1;
DE   AltName: Full=Tax-binding protein 181;
GN   Name=MAD1L1; Synonyms=MAD1, TXBP181;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000090; P:mitotic anaphase; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; NAS:UniProtKB.
DR   GO; GO:0000089; P:mitotic metaphase; NAS:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0000093; P:mitotic telophase; NAS:UniProtKB.
DR   GO; GO:0090235; P:regulation of metaphase plate congression; IDA:UniProtKB.
//
ID   MD2BP_HUMAN             Reviewed;         274 AA.
AC   Q15013; B4DLV3; E9PAT7; Q6IBB1;
DE   RecName: Full=MAD2L1-binding protein;
DE   AltName: Full=Caught by MAD2 protein;
GN   Name=MAD2L1BP; Synonyms=CMT2, KIAA0110;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0007096; P:regulation of exit from mitosis; IMP:UniProtKB.
//
ID   MD2L1_HUMAN             Reviewed;         205 AA.
AC   Q13257; Q53F56; Q548X9; Q6IRW7; Q8IZX3;
DE   RecName: Full=Mitotic spindle assembly checkpoint protein MAD2A;
DE            Short=HsMAD2;
DE   AltName: Full=Mitotic arrest deficient 2-like protein 1;
DE            Short=MAD2-like protein 1;
GN   Name=MAD2L1; Synonyms=MAD2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:Ensembl.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
//
ID   MD2L2_HUMAN             Reviewed;         211 AA.
AC   Q9UI95; B3KNE3; Q5TGW7; Q9UNA7; Q9Y6I6;
DE   RecName: Full=Mitotic spindle assembly checkpoint protein MAD2B;
DE   AltName: Full=Mitotic arrest deficient 2-like protein 2;
DE            Short=MAD2-like protein 2;
DE   AltName: Full=REV7 homolog;
DE            Short=hREV7;
GN   Name=MAD2L2; Synonyms=MAD2B, REV7;
DR   GO; GO:0008432; F:JUN kinase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0007015; P:actin filament organization; IMP:BHF-UCL.
DR   GO; GO:0042772; P:DNA damage response, signal transduction resulting in transcription; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IGI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:ProtInc.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:2000048; P:negative regulation of cell-cell adhesion mediated by cadherin; IMP:BHF-UCL.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IMP:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; IGI:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MDC1_HUMAN              Reviewed;        2089 AA.
AC   Q14676; A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; Q0EFC2; Q2L6H7;
AC   Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2;
DE   RecName: Full=Mediator of DNA damage checkpoint protein 1;
DE   AltName: Full=Nuclear factor with BRCT domains 1;
GN   Name=MDC1; Synonyms=KIAA0170, NFBD1;
DR   GO; GO:0070975; F:FHA domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; TAS:UniProtKB.
//
ID   MDFIC_HUMAN             Reviewed;         246 AA.
AC   Q9P1T7; Q9P1T6;
DE   RecName: Full=MyoD family inhibitor domain-containing protein;
DE   AltName: Full=I-mfa domain-containing protein;
DE            Short=hIC;
GN   Name=MDFIC;
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030957; F:Tat protein binding; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0042308; P:negative regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; IDA:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MDFI_HUMAN              Reviewed;         246 AA.
AC   Q99750;
DE   RecName: Full=MyoD family inhibitor;
DE   AltName: Full=Myogenic repressor I-mf;
GN   Name=MDFI;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; TAS:ProtInc.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
//
ID   MDGA1_HUMAN             Reviewed;         955 AA.
AC   Q8NFP4; A6NHG0; Q8NBE3;
DE   RecName: Full=MAM domain-containing glycosylphosphatidylinositol anchor protein 1;
DE   AltName: Full=GPI and MAM protein;
DE            Short=GPIM;
DE   AltName: Full=Glycosylphosphatidylinositol-MAM;
DE   AltName: Full=MAM domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=MDGA1; Synonyms=MAMDC3;
DR   GO; GO:0007420; P:brain development; ISS:HGNC.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; ISS:HGNC.
//
ID   MDGA2_HUMAN             Reviewed;         956 AA.
AC   Q7Z553; F6W3S7; J3KPX6;
DE   RecName: Full=MAM domain-containing glycosylphosphatidylinositol anchor protein 2;
DE   AltName: Full=MAM domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=MDGA2; Synonyms=MAMDC1; ORFNames=UNQ8188/PRO23197;
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; ISS:HGNC.
//
ID   MDH1B_HUMAN             Reviewed;         518 AA.
AC   Q5I0G3; A8K8M1; Q53TK9; Q8IV51;
DE   RecName: Full=Putative malate dehydrogenase 1B;
DE            EC=1.1.1.-;
GN   Name=MDH1B;
DR   GO; GO:0016615; F:malate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006108; P:malate metabolic process; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
//
ID   MDHC_HUMAN              Reviewed;         334 AA.
AC   P40925; B2R5V5; B4DUN2; B7Z3I7; F5H098; Q6I9V0;
DE   RecName: Full=Malate dehydrogenase, cytoplasmic;
DE            EC=1.1.1.37;
DE   AltName: Full=Cytosolic malate dehydrogenase;
DE   AltName: Full=Diiodophenylpyruvate reductase;
DE            EC=1.1.1.96;
GN   Name=MDH1; Synonyms=MDHA;
DR   GO; GO:0047860; F:diiodophenylpyruvate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030060; F:L-malate dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0004470; F:malic enzyme activity; TAS:ProtInc.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006108; P:malate metabolic process; IEA:Ensembl.
DR   GO; GO:0006734; P:NADH metabolic process; IEA:Ensembl.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
//
ID   MDHM_HUMAN              Reviewed;         338 AA.
AC   P40926; A8K414; B2RE78; O43682;
DE   RecName: Full=Malate dehydrogenase, mitochondrial;
DE            EC=1.1.1.37;
DE   Flags: Precursor;
GN   Name=MDH2;
DR   GO; GO:0030060; F:L-malate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0046554; F:malate dehydrogenase (NADP+) activity; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; IDA:UniProtKB.
DR   GO; GO:0006108; P:malate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006734; P:NADH metabolic process; IEA:Ensembl.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   MDM1_HUMAN              Reviewed;         714 AA.
AC   Q8TC05; B4DM65; E7EPQ3; O43406; Q8WTV9; Q9NR04;
DE   RecName: Full=Nuclear protein MDM1;
GN   Name=MDM1;
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
//
ID   MDM2_HUMAN              Reviewed;         491 AA.
AC   Q00987; A6NL51; A8K2S6; Q13226; Q13297; Q13298; Q13299; Q13300;
AC   Q13301; Q53XW0; Q71TW9; Q8WYJ1; Q8WYJ2; Q9UGI3; Q9UMT8;
DE   RecName: Full=E3 ubiquitin-protein ligase Mdm2;
DE            EC=6.3.2.-;
DE   AltName: Full=Double minute 2 protein;
DE            Short=Hdm2;
DE   AltName: Full=Oncoprotein Mdm2;
DE   AltName: Full=p53-binding protein Mdm2;
GN   Name=MDM2;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0071229; P:cellular response to acid; IEA:Ensembl.
DR   GO; GO:0071312; P:cellular response to alkaloid; IEA:Ensembl.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071494; P:cellular response to UV-C; IEA:Ensembl.
DR   GO; GO:0071301; P:cellular response to vitamin B1; IEA:Ensembl.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045184; P:establishment of protein localization; IDA:BHF-UCL.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0010955; P:negative regulation of protein processing; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018205; P:peptidyl-lysine modification; IMP:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IDA:BHF-UCL.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:BHF-UCL.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IEP:UniProtKB.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045472; P:response to ether; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007089; P:traversing start control point of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MDM4_HUMAN              Reviewed;         490 AA.
AC   O15151; Q2M2Y2; Q32SL2; Q6GS18; Q8IV83;
DE   RecName: Full=Protein Mdm4;
DE   AltName: Full=Double minute 4 protein;
DE   AltName: Full=Mdm2-like p53-binding protein;
DE   AltName: Full=Protein Mdmx;
DE   AltName: Full=p53-binding protein Mdm4;
GN   Name=MDM4; Synonyms=MDMX;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEP:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IEP:UniProtKB.
DR   GO; GO:0045023; P:G0 to G1 transition; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IEA:InterPro.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IEP:UniProtKB.
//
ID   MDN1_HUMAN              Reviewed;        5596 AA.
AC   Q9NU22; O15019; Q5T794;
DE   RecName: Full=Midasin;
DE   AltName: Full=MIDAS-containing protein;
GN   Name=MDN1; Synonyms=KIAA0301;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
//
ID   MDR1_HUMAN              Reviewed;        1280 AA.
AC   P08183; A8K294; Q12755; Q14812;
DE   RecName: Full=Multidrug resistance protein 1;
DE            EC=3.6.3.44;
DE   AltName: Full=ATP-binding cassette sub-family B member 1;
DE   AltName: Full=P-glycoprotein 1;
DE   AltName: CD_antigen=CD243;
GN   Name=ABCB1; Synonyms=MDR1, PGY1;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006855; P:drug transmembrane transport; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:DFLAT.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0072089; P:stem cell proliferation; IMP:DFLAT.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MDR3_HUMAN              Reviewed;        1286 AA.
AC   P21439; A0A2V7; A4D1D3; A4D1D4; A4D1D5; D6W5P3; D6W5P4; Q14813;
DE   RecName: Full=Multidrug resistance protein 3;
DE            EC=3.6.3.44;
DE   AltName: Full=ATP-binding cassette sub-family B member 4;
DE   AltName: Full=P-glycoprotein 3;
GN   Name=ABCB4; Synonyms=MDR3, PGY3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IBA:RefGenome.
DR   GO; GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MDS1_HUMAN              Reviewed;         169 AA.
AC   Q13465; Q13466; Q6FH90;
DE   RecName: Full=MDS1 and EVI1 complex locus protein MDS1;
DE   AltName: Full=Myelodysplasia syndrome 1 protein;
DE   AltName: Full=Myelodysplasia syndrome-associated protein 1;
GN   Name=MECOM; Synonyms=MDS1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
//
ID   MDS2_HUMAN              Reviewed;         140 AA.
AC   Q8NDY4;
DE   RecName: Full=Myelodysplastic syndrome 2 translocation-associated protein;
GN   Name=MDS2;
//
ID   ME3L1_HUMAN             Reviewed;         274 AA.
AC   A6NDR6;
DE   RecName: Full=Putative homeobox protein Meis3-like 1;
GN   Name=MEIS3P1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   ME3L2_HUMAN             Reviewed;         358 AA.
AC   A8K0S8;
DE   RecName: Full=Putative homeobox protein Meis3-like 2;
GN   Name=MEIS3P2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   MEA1_HUMAN              Reviewed;         185 AA.
AC   Q16626; Q5TC36; Q9BV01;
DE   RecName: Full=Male-enhanced antigen 1;
DE            Short=MEA-1;
GN   Name=MEA1; Synonyms=MEA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   ME15P_HUMAN             Reviewed;         234 AA.
AC   P0C7V9;
DE   RecName: Full=Putative methyltransferase-like protein 15P1;
DE            EC=2.1.1.-;
DE   AltName: Full=Methyltransferase 5 domain-containing protein 2;
DE   AltName: Full=Methyltransferase-like protein 15 pseudogene 1;
GN   Name=METTL15P1; Synonyms=METT5D2;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MECP2_HUMAN             Reviewed;         486 AA.
AC   P51608; O15233; Q6QHH9; Q7Z384;
DE   RecName: Full=Methyl-CpG-binding protein 2;
DE            Short=MeCp-2 protein;
DE            Short=MeCp2;
GN   Name=MECP2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0010385; F:double-stranded methylated DNA binding; IMP:MGI.
DR   GO; GO:0008327; F:methyl-CpG binding; IEA:Ensembl.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0035197; F:siRNA binding; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0032048; P:cardiolipin metabolic process; IEA:Ensembl.
DR   GO; GO:0050432; P:catecholamine secretion; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0006342; P:chromatin silencing; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0008211; P:glucocorticoid metabolic process; IEA:Ensembl.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:Ensembl.
DR   GO; GO:0016573; P:histone acetylation; IEA:Ensembl.
DR   GO; GO:0016571; P:histone methylation; IEA:Ensembl.
DR   GO; GO:0006020; P:inositol metabolic process; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:Ensembl.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0031061; P:negative regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001976; P:neurological system process involved in regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0009405; P:pathogenesis; IEA:Ensembl.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0019230; P:proprioception; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   MECR_HUMAN              Reviewed;         373 AA.
AC   Q9BV79; B3KT72; Q5SYU0; Q5SYU1; Q5SYU2; Q6IBU9; Q9Y373;
DE   RecName: Full=Trans-2-enoyl-CoA reductase, mitochondrial;
DE            EC=1.3.1.38;
DE   AltName: Full=Nuclear receptor-binding factor 1;
DE            Short=HsNrbf-1;
DE            Short=NRBF-1;
DE   Flags: Precursor;
GN   Name=MECR; Synonyms=NBRF1; ORFNames=CGI-63;
DR   GO; GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:UniProtKB.
//
ID   MED10_HUMAN             Reviewed;         135 AA.
AC   Q9BTT4; C6G491;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 10;
DE   AltName: Full=Mediator complex subunit 10;
DE   AltName: Full=Transformation-related gene 17 protein;
DE            Short=TRG-17;
DE   AltName: Full=Transformation-related gene 20 protein;
DE            Short=TRG-20;
GN   Name=MED10; ORFNames=L6, TRG17, TRG20;
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED11_HUMAN             Reviewed;         117 AA.
AC   Q9P086; Q6NS89;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 11;
DE   AltName: Full=Mediator complex subunit 11;
GN   Name=MED11; ORFNames=HSPC296;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MED12_HUMAN             Reviewed;        2177 AA.
AC   Q93074; O15410; O75557; Q9UHV6; Q9UND7;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 12;
DE   AltName: Full=Activator-recruited cofactor 240 kDa component;
DE            Short=ARC240;
DE   AltName: Full=CAG repeat protein 45;
DE   AltName: Full=Mediator complex subunit 12;
DE   AltName: Full=OPA-containing protein;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 230 kDa component;
DE            Short=Trap230;
DE   AltName: Full=Trinucleotide repeat-containing gene 11 protein;
GN   Name=MED12; Synonyms=ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0090245; P:axis elongation involved in somitogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0014044; P:Schwann cell development; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   MED13_HUMAN             Reviewed;        2174 AA.
AC   Q9UHV7; B2RU05; O60334;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 13;
DE   AltName: Full=Activator-recruited cofactor 250 kDa component;
DE            Short=ARC250;
DE   AltName: Full=Mediator complex subunit 13;
DE   AltName: Full=Thyroid hormone receptor-associated protein 1;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 240 kDa component;
DE            Short=Trap240;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex component DRIP250;
DE            Short=DRIP250;
GN   Name=MED13; Synonyms=ARC250, KIAA0593, THRAP1, TRAP240;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED14_HUMAN             Reviewed;        1454 AA.
AC   O60244; Q4KMR7; Q9UNB3;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 14;
DE   AltName: Full=Activator-recruited cofactor 150 kDa component;
DE            Short=ARC150;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 2;
DE            Short=CRSP complex subunit 2;
DE   AltName: Full=Mediator complex subunit 14;
DE   AltName: Full=RGR1 homolog;
DE            Short=hRGR1;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 170 kDa component;
DE            Short=Trap170;
DE   AltName: Full=Transcriptional coactivator CRSP150;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex 150 kDa component;
DE            Short=DRIP150;
GN   Name=MED14;
GN   Synonyms=ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED15_HUMAN             Reviewed;         788 AA.
AC   Q96RN5; D3DX31; D3DX32; O15413; Q6IC31; Q8NF16; Q96CT0; Q96IH7;
AC   Q9P1T3;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 15;
DE   AltName: Full=Activator-recruited cofactor 105 kDa component;
DE            Short=ARC105;
DE   AltName: Full=CTG repeat protein 7a;
DE   AltName: Full=Mediator complex subunit 15;
DE   AltName: Full=Positive cofactor 2 glutamine/Q-rich-associated protein;
DE            Short=PC2 glutamine/Q-rich-associated protein;
DE   AltName: Full=TPA-inducible gene 1 protein;
DE            Short=TIG-1;
DE   AltName: Full=Trinucleotide repeat-containing gene 7 protein;
GN   Name=MED15; Synonyms=ARC105, CTG7A, PCQAP, TIG1, TNRC7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED16_HUMAN             Reviewed;         877 AA.
AC   Q9Y2X0; Q6PJT2; Q96AD4; Q96I35; Q9Y652;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 16;
DE   AltName: Full=Mediator complex subunit 16;
DE   AltName: Full=Thyroid hormone receptor-associated protein 5;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 95 kDa component;
DE            Short=Trap95;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex 92 kDa component;
DE            Short=DRIP92;
GN   Name=MED16; Synonyms=DRIP92, THRAP5;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0030375; F:thyroid hormone receptor coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000273; P:positive regulation of receptor activity; IDA:GOC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED17_HUMAN             Reviewed;         651 AA.
AC   Q9NVC6; B3KN07; Q9HA81; Q9UNP7; Q9Y2W0; Q9Y660;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 17;
DE   AltName: Full=Activator-recruited cofactor 77 kDa component;
DE            Short=ARC77;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 6;
DE            Short=CRSP complex subunit 6;
DE   AltName: Full=Mediator complex subunit 17;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 80 kDa component;
DE            Short=Trap80;
DE   AltName: Full=Transcriptional coactivator CRSP77;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex 80 kDa component;
DE            Short=DRIP80;
GN   Name=MED17; Synonyms=ARC77, CRSP6, DRIP77, DRIP80, TRAP80;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED18_HUMAN             Reviewed;         208 AA.
AC   Q9BUE0; D3DPM1; Q9NXU9;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 18;
DE   AltName: Full=Mediator complex subunit 18;
DE   AltName: Full=p28b;
GN   Name=MED18;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MED19_HUMAN             Reviewed;         244 AA.
AC   A0JLT2; Q8IV02; Q8IZD1;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 19;
DE   AltName: Full=Lung cancer metastasis-related protein 1;
DE   AltName: Full=Mediator complex subunit 19;
GN   Name=MED19; Synonyms=LCMR1;
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MED1_HUMAN              Reviewed;        1581 AA.
AC   Q15648; A2RRQ6; O43810; O75447; Q6P9H7; Q6PK58; Q9HD39;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 1;
DE   AltName: Full=Activator-recruited cofactor 205 kDa component;
DE            Short=ARC205;
DE   AltName: Full=Mediator complex subunit 1;
DE   AltName: Full=Peroxisome proliferator-activated receptor-binding protein;
DE            Short=PBP;
DE            Short=PPAR-binding protein;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 220 kDa component;
DE            Short=Trap220;
DE   AltName: Full=Thyroid receptor-interacting protein 2;
DE            Short=TR-interacting protein 2;
DE            Short=TRIP-2;
DE   AltName: Full=Vitamin D receptor-interacting protein complex component DRIP205;
DE   AltName: Full=p53 regulatory protein RB18A;
GN   Name=MED1;
GN   Synonyms=ARC205, CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP,
GN   PPARGBP, RB18A, TRAP220, TRIP2;
DR   GO; GO:0003682; F:chromatin binding; IMP:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.
DR   GO; GO:0050693; F:LBD domain binding; IPI:UniProtKB.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0036033; F:mediator complex binding; IDA:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0030375; F:thyroid hormone receptor coactivator activity; IMP:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; IPI:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0048822; P:enucleate erythrocyte development; IEA:Ensembl.
DR   GO; GO:0060750; P:epithelial cell proliferation involved in mammary gland duct elongation; IEA:Ensembl.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0048821; P:erythrocyte development; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IDA:MGI.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0060745; P:mammary gland branching involved in pregnancy; IEA:Ensembl.
DR   GO; GO:0060744; P:mammary gland branching involved in thelarche; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; ISS:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0035357; P:peroxisome proliferator activated receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0070318; P:positive regulation of G0 to G1 transition; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2000347; P:positive regulation of hepatocyte proliferation; IEA:Ensembl.
DR   GO; GO:0060335; P:positive regulation of interferon-gamma-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:2000273; P:positive regulation of receptor activity; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; NAS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006356; P:regulation of transcription from RNA polymerase I promoter; IDA:UniProtKB.
DR   GO; GO:0070562; P:regulation of vitamin D receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0003406; P:retinal pigment epithelium development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; IEA:Ensembl.
DR   GO; GO:0002154; P:thyroid hormone mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
//
ID   MED20_HUMAN             Reviewed;         212 AA.
AC   Q9H944; O95821; Q5T8J4; Q9Y429;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 20;
DE   AltName: Full=Mediator complex subunit 20;
DE   AltName: Full=TRF-proximal protein homolog;
DE            Short=hTRFP;
GN   Name=MED20; Synonyms=TRFP;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   MED21_HUMAN             Reviewed;         144 AA.
AC   Q13503; B2R4I3; Q6IB05; Q92811;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 21;
DE   AltName: Full=Mediator complex subunit 21;
DE   AltName: Full=RNA polymerase II holoenzyme component SRB7;
DE            Short=RNAPII complex component SRB7;
DE            Short=hSrb7;
GN   Name=MED21; Synonyms=SRB7, SURB7;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MED22_HUMAN             Reviewed;         200 AA.
AC   Q15528; B3KW83; B3KWX4; O76072; Q5T8U0;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 22;
DE   AltName: Full=Mediator complex subunit 22;
DE   AltName: Full=Surfeit locus protein 5;
DE            Short=Surf-5;
GN   Name=MED22; Synonyms=SURF5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MED23_HUMAN             Reviewed;        1368 AA.
AC   Q9ULK4; B9TX55; O95403; Q5JWT3; Q5JWT4; Q6P9H6; Q9H0J2; Q9NTT9;
AC   Q9NTU0; Q9Y5P7; Q9Y667;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 23;
DE   AltName: Full=Activator-recruited cofactor 130 kDa component;
DE            Short=ARC130;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 3;
DE            Short=CRSP complex subunit 3;
DE   AltName: Full=Mediator complex subunit 23;
DE   AltName: Full=Protein sur-2 homolog;
DE            Short=hSur-2;
DE   AltName: Full=Transcriptional coactivator CRSP130;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex 130 kDa component;
DE            Short=DRIP130;
GN   Name=MED23; Synonyms=ARC130, CRSP3, DRIP130, KIAA1216, SUR2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED24_HUMAN             Reviewed;         989 AA.
AC   O75448; A8K4S5; B3KMR9; Q14143; Q9NNY5;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 24;
DE   AltName: Full=Activator-recruited cofactor 100 kDa component;
DE            Short=ARC100;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 4;
DE            Short=CRSP complex subunit 4;
DE   AltName: Full=Mediator complex subunit 24;
DE   AltName: Full=Thyroid hormone receptor-associated protein 4;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 100 kDa component;
DE            Short=Trap100;
DE            Short=hTRAP100;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex 100 kDa component;
DE            Short=DRIP100;
GN   Name=MED24;
GN   Synonyms=ARC100, CRSP4, DRIP100, KIAA0130, THRAP4, TRAP100;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:Ensembl.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED25_HUMAN             Reviewed;         747 AA.
AC   Q71SY5; A8K095; B9TX30; O95783; Q6P143; Q6QMH5; Q707U4; Q8TB55;
AC   Q9H0L5; Q9HB34;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 25;
DE   AltName: Full=Activator interaction domain-containing protein 1;
DE   AltName: Full=Activator-recruited cofactor 92 kDa component;
DE            Short=ARC92;
DE   AltName: Full=Mediator complex subunit 25;
DE   AltName: Full=p78;
GN   Name=MED25; Synonyms=ACID1, ARC92, PTOV2; ORFNames=TCBAP0758;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.
DR   GO; GO:0046965; F:retinoid X receptor binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0035563; P:positive regulation of chromatin binding; IMP:UniProtKB.
DR   GO; GO:2001178; P:positive regulation of mediator complex assembly; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED26_HUMAN             Reviewed;         600 AA.
AC   O95402; A1A4S3; Q0VGB6;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 26;
DE   AltName: Full=Activator-recruited cofactor 70 kDa component;
DE            Short=ARC70;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 7;
DE            Short=CRSP complex subunit 7;
DE   AltName: Full=Mediator complex subunit 26;
DE   AltName: Full=Transcriptional coactivator CRSP70;
GN   Name=MED26; Synonyms=ARC70, CRSP7;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED27_HUMAN             Reviewed;         311 AA.
AC   Q6P2C8; O95401; Q4F964; Q5VTA4; Q5VTA5; Q9BU57; Q9NYR4;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 27;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 8;
DE            Short=CRSP complex subunit 8;
DE   AltName: Full=Mediator complex subunit 27;
DE   AltName: Full=P37 TRAP/SMCC/PC2 subunit;
DE   AltName: Full=Transcriptional coactivator CRSP34;
GN   Name=MED27; Synonyms=CRSP34, CRSP8;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED28_HUMAN             Reviewed;         178 AA.
AC   Q9H204; Q9BZJ5;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 28;
DE   AltName: Full=Endothelial-derived protein 1;
DE   AltName: Full=Mediator complex subunit 28;
DE   AltName: Full=Merlin and Grb2-interacting cytoskeletal protein;
DE            Short=Magicin;
DE   AltName: Full=Tumor angiogenesis marker EG-1;
GN   Name=MED28; Synonyms=EG1; ORFNames=FKSG20;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051151; P:negative regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MED29_HUMAN             Reviewed;         200 AA.
AC   Q9NX70; Q5XX09; Q9NTF4;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 29;
DE   AltName: Full=Intersex-like protein;
DE   AltName: Full=Mediator complex subunit 29;
GN   Name=MED29; Synonyms=IXL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MED30_HUMAN             Reviewed;         178 AA.
AC   Q96HR3; C6GKU9;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 30;
DE   AltName: Full=Mediator complex subunit 30;
DE   AltName: Full=TRAP/Mediator complex component TRAP25;
DE   AltName: Full=Thyroid hormone receptor-associated protein 6;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 25 kDa component;
DE            Short=Trap25;
GN   Name=MED30; Synonyms=THRAP6, TRAP25;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED31_HUMAN             Reviewed;         131 AA.
AC   Q9Y3C7; B2R4L9;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 31;
DE   AltName: Full=Mediator complex subunit 31;
DE   AltName: Full=Mediator complex subunit SOH1;
DE            Short=hSOH1;
GN   Name=MED31; Synonyms=SOH1; ORFNames=CGI-125;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0060173; P:limb development; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED4_HUMAN              Reviewed;         270 AA.
AC   Q9NPJ6; B4DX67; Q53GB4; Q53H68; Q5T912; Q6FHC4; Q6IA79; Q9BS95;
AC   Q9NYR5;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 4;
DE   AltName: Full=Activator-recruited cofactor 36 kDa component;
DE            Short=ARC36;
DE   AltName: Full=Mediator complex subunit 4;
DE   AltName: Full=TRAP/SMCC/PC2 subunit p36 subunit;
DE   AltName: Full=Vitamin D3 receptor-interacting protein complex 36 kDa component;
DE            Short=DRIP36;
GN   Name=MED4; Synonyms=ARC36, DRIP36, VDRIP; ORFNames=HSPC126;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   MED6_HUMAN              Reviewed;         246 AA.
AC   O75586; B4DU17; B4E2P0; O15401; Q53FE3; Q53HJ3; Q6FHQ4; Q9BTH1;
AC   Q9UHL1;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 6;
DE   AltName: Full=Activator-recruited cofactor 33 kDa component;
DE            Short=ARC33;
DE   AltName: Full=Mediator complex subunit 6;
DE            Short=hMed6;
DE   AltName: Full=Renal carcinoma antigen NY-REN-28;
GN   Name=MED6; Synonyms=ARC33;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED7_HUMAN              Reviewed;         233 AA.
AC   O43513;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 7;
DE            Short=hMED7;
DE   AltName: Full=Activator-recruited cofactor 34 kDa component;
DE            Short=ARC34;
DE   AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 9;
DE            Short=CRSP complex subunit 9;
DE   AltName: Full=Mediator complex subunit 7;
DE   AltName: Full=RNA polymerase transcriptional regulation mediator subunit 7 homolog;
DE   AltName: Full=Transcriptional coactivator CRSP33;
GN   Name=MED7; Synonyms=ARC34, CRSP9;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED8_HUMAN              Reviewed;         268 AA.
AC   Q96G25; A9IZ91; A9IZ92; Q5JUY8; Q96FQ4;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 8;
DE   AltName: Full=Activator-recruited cofactor 32 kDa component;
DE            Short=ARC32;
DE   AltName: Full=Mediator complex subunit 8;
GN   Name=MED8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   MED9_HUMAN              Reviewed;         146 AA.
AC   Q9NWA0;
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9;
DE   AltName: Full=Mediator complex subunit 9;
GN   Name=MED9; Synonyms=MED25;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
//
ID   MEDAG_HUMAN             Reviewed;         303 AA.
AC   Q5VYS4; Q8IXF1; Q96K26; Q96NC8;
DE   RecName: Full=Mesenteric estrogen-dependent adipogenesis protein;
DE   AltName: Full=Activated in W/Wv mouse stomach 3 homolog;
DE            Short=hAWMS3;
DE   AltName: Full=Mesenteric estrogen-dependent adipose 4;
DE            Short=MEDA-4;
GN   Name=MEDAG; Synonyms=AWMS3, C13orf33, MEDA4;
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
//
ID   MEF2A_HUMAN             Reviewed;         507 AA.
AC   Q02078; B4DFQ7; F6XG23; O43814; Q14223; Q14224; Q59GX4; Q7Z6C9;
AC   Q96D14;
DE   RecName: Full=Myocyte-specific enhancer factor 2A;
DE   AltName: Full=Serum response factor-like protein 1;
GN   Name=MEF2A; Synonyms=MEF2;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0061337; P:cardiac conduction; ISS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0070375; P:ERK5 cascade; IMP:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; ISS:UniProtKB.
DR   GO; GO:0048311; P:mitochondrion distribution; ISS:UniProtKB.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; NAS:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055005; P:ventricular cardiac myofibril assembly; ISS:UniProtKB.
//
ID   MEF2B_HUMAN             Reviewed;         365 AA.
AC   Q02080; A0AV80; B4DVH7; B7ZVY1; G5E9M1;
DE   RecName: Full=Myocyte-specific enhancer factor 2B;
DE   AltName: Full=RSRFR2;
DE   AltName: Full=Serum response factor-like protein 2;
GN   Name=MEF2B; Synonyms=XMEF2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MEF2C_HUMAN             Reviewed;         473 AA.
AC   Q06413; C9JMZ0; D7F7N5; F8W7V7;
DE   RecName: Full=Myocyte-specific enhancer factor 2C;
GN   Name=MEF2C;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003680; F:AT DNA binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0035198; F:miRNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0001782; P:B cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0042100; P:B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; ISS:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:UniProtKB.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; ISS:UniProtKB.
DR   GO; GO:0071498; P:cellular response to fluid shear stress; ISS:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0071374; P:cellular response to parathyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.
DR   GO; GO:0035984; P:cellular response to trichostatin A; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; ISS:UniProtKB.
DR   GO; GO:2001013; P:epithelial cell proliferation involved in renal tubule morphogenesis; ISS:UniProtKB.
DR   GO; GO:0002467; P:germinal center formation; ISS:UniProtKB.
DR   GO; GO:0072102; P:glomerulus morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; ISS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; ISS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007521; P:muscle cell fate determination; ISS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0014902; P:myotube differentiation; IEP:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0030279; P:negative regulation of ossification; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0072160; P:nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0014033; P:neural crest cell differentiation; ISS:UniProtKB.
DR   GO; GO:0048666; P:neuron development; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IEP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0030220; P:platelet formation; ISS:UniProtKB.
DR   GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:2000987; P:positive regulation of behavioral fear response; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:2000727; P:positive regulation of cardiac muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:0071864; P:positive regulation of cell proliferation in bone marrow; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2000111; P:positive regulation of macrophage apoptotic process; ISS:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0090073; P:positive regulation of protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:2001016; P:positive regulation of skeletal muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0003138; P:primary heart field specification; ISS:UniProtKB.
DR   GO; GO:0002634; P:regulation of germinal center formation; ISS:UniProtKB.
DR   GO; GO:0045652; P:regulation of megakaryocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0060297; P:regulation of sarcomere organization; IEA:Ensembl.
DR   GO; GO:0060025; P:regulation of synaptic activity; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0061333; P:renal tubule morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0033197; P:response to vitamin E; IEA:Ensembl.
DR   GO; GO:0003139; P:secondary heart field specification; ISS:UniProtKB.
DR   GO; GO:0003185; P:sinoatrial valve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; ISS:UniProtKB.
//
ID   MEF2D_HUMAN             Reviewed;         521 AA.
AC   Q14814; D3DVC0; Q14815; Q5T9U5; Q5T9U6;
DE   RecName: Full=Myocyte-specific enhancer factor 2D;
GN   Name=MEF2D;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0007512; P:adult heart development; IEP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   MEFV_HUMAN              Reviewed;         781 AA.
AC   O15553; D3DUC0; F5H0Q3; Q3MJ84; Q96PN4; Q96PN5;
DE   RecName: Full=Pyrin;
DE   AltName: Full=Marenostrin;
GN   Name=MEFV; Synonyms=MEF;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IMP:BHF-UCL.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IMP:BHF-UCL.
DR   GO; GO:0071641; P:negative regulation of macrophage inflammatory protein 1 alpha production; IMP:BHF-UCL.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2001056; P:positive regulation of cysteine-type endopeptidase activity; IDA:UniProtKB.
//
ID   MEG10_HUMAN             Reviewed;        1140 AA.
AC   Q96KG7; Q68DE5; Q8WUL3;
DE   RecName: Full=Multiple epidermal growth factor-like domains protein 10;
DE            Short=Multiple EGF-like domains protein 10;
DE   Flags: Precursor;
GN   Name=MEGF10; Synonyms=KIAA1780;
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0055001; P:muscle cell development; IMP:UniProtKB.
DR   GO; GO:0043654; P:recognition of apoptotic cell; IEA:Ensembl.
DR   GO; GO:0051147; P:regulation of muscle cell differentiation; IMP:UniProtKB.
DR   GO; GO:0048641; P:regulation of skeletal muscle tissue development; IMP:UniProtKB.
DR   GO; GO:0014719; P:satellite cell activation; ISS:UniProtKB.
DR   GO; GO:0014816; P:satellite cell differentiation; IMP:UniProtKB.
DR   GO; GO:0014841; P:satellite cell proliferation; ISS:UniProtKB.
//
ID   MEG11_HUMAN             Reviewed;        1044 AA.
AC   A6BM72; Q17R86; Q6UXS5; Q8ND91; Q96KG6;
DE   RecName: Full=Multiple epidermal growth factor-like domains protein 11;
DE            Short=Multiple EGF-like domains protein 11;
DE   Flags: Precursor;
GN   Name=MEGF11; Synonyms=KIAA1781; ORFNames=UNQ1949/PRO4432;
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
//
ID   MEGF6_HUMAN             Reviewed;        1541 AA.
AC   O75095; Q4AC86; Q5VV39;
DE   RecName: Full=Multiple epidermal growth factor-like domains protein 6;
DE            Short=Multiple EGF-like domains protein 6;
DE   AltName: Full=Epidermal growth factor-like protein 3;
DE            Short=EGF-like protein 3;
DE   Flags: Precursor;
GN   Name=MEGF6; Synonyms=EGFL3, KIAA0815;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MEI4L_HUMAN             Reviewed;         385 AA.
AC   A8MW99; R4GMV8;
DE   RecName: Full=Meiosis-specific protein MEI4-like;
GN   Name=MEI4;
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; ISS:UniProtKB.
DR   GO; GO:0048477; P:oogenesis; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007129; P:synapsis; ISS:UniProtKB.
//
ID   MEGF8_HUMAN             Reviewed;        2845 AA.
AC   Q7Z7M0; A8KAY0; O75097;
DE   RecName: Full=Multiple epidermal growth factor-like domains protein 8;
DE            Short=Multiple EGF-like domains protein 8;
DE   AltName: Full=Epidermal growth factor-like protein 4;
DE            Short=EGF-like protein 4;
DE   Flags: Precursor;
GN   Name=MEGF8; Synonyms=C19orf49, EGFL4, KIAA0817;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:UniProt.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IMP:UniProt.
DR   GO; GO:0097094; P:craniofacial suture morphogenesis; IMP:UniProt.
DR   GO; GO:0071907; P:determination of digestive tract left/right asymmetry; ISS:UniProt.
DR   GO; GO:0061371; P:determination of heart left/right asymmetry; IMP:UniProt.
DR   GO; GO:0060971; P:embryonic heart tube left/right pattern formation; ISS:UniProt.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; ISS:UniProt.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:UniProt.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProt.
DR   GO; GO:0055113; P:epiboly involved in gastrulation with mouth forming second; IMP:UniProt.
DR   GO; GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProt.
DR   GO; GO:0060972; P:left/right pattern formation; IMP:UniProt.
DR   GO; GO:0035108; P:limb morphogenesis; IMP:UniProt.
DR   GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; ISS:UniProt.
DR   GO; GO:0010468; P:regulation of gene expression; ISS:UniProt.
//
ID   MEGF9_HUMAN             Reviewed;         602 AA.
AC   Q9H1U4; B7Z315; O75098;
DE   RecName: Full=Multiple epidermal growth factor-like domains protein 9;
DE            Short=Multiple EGF-like domains protein 9;
DE   AltName: Full=Epidermal growth factor-like protein 5;
DE            Short=EGF-like protein 5;
DE   Flags: Precursor;
GN   Name=MEGF9; Synonyms=EGFL5, KIAA0818; ORFNames=UNQ671/PRO1305;
//
ID   MEI1_HUMAN              Reviewed;        1274 AA.
AC   Q5TIA1; B7Z745; Q1XAP1; Q1XAP2; Q8IYJ5; Q8N5K5; Q8N9H3; Q8TC68;
DE   RecName: Full=Meiosis inhibitor protein 1;
DE   AltName: Full=Meiosis defective protein 1;
GN   Name=MEI1;
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   MEIG1_HUMAN             Reviewed;          88 AA.
AC   Q5JSS6;
DE   RecName: Full=Meiosis expressed gene 1 protein homolog;
GN   Name=MEIG1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   MEIOB_HUMAN             Reviewed;         442 AA.
AC   Q8N635; B1AK39; C9J0S1; Q96RY0;
DE   RecName: Full=Meiosis-specific with OB domain-containing protein;
DE            EC=3.1.-.-;
GN   Name=MEIOB; Synonyms=C16orf73;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0008310; F:single-stranded DNA 3'-5' exodeoxyribonuclease activity; ISS:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; ISS:GOC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.
DR   GO; GO:0007144; P:female meiosis I; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; ISS:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; ISS:UniProtKB.
DR   GO; GO:0007129; P:synapsis; ISS:UniProtKB.
//
ID   MEIS1_HUMAN             Reviewed;         390 AA.
AC   O00470; A8MV50;
DE   RecName: Full=Homeobox protein Meis1;
GN   Name=MEIS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MEIS2_HUMAN             Reviewed;         477 AA.
AC   O14770; A6NJI5; A8MWD5; B3KP98; B3KPQ6; Q96DI2; Q96KI4; Q96KI5;
AC   Q9NRS1; Q9NRS2; Q9NRS3;
DE   RecName: Full=Homeobox protein Meis2;
DE   AltName: Full=Meis1-related protein 1;
GN   Name=MEIS2; Synonyms=MRG1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0001654; P:eye development; IEA:Ensembl.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0070848; P:response to growth factor; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MEIS3_HUMAN             Reviewed;         375 AA.
AC   Q99687; A8K1N5; Q6NT73; Q8TC66; Q9NPW2;
DE   RecName: Full=Homeobox protein Meis3;
DE   AltName: Full=Meis1-related protein 2;
GN   Name=MEIS3; Synonyms=MRG2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
//
ID   MELK_HUMAN              Reviewed;         651 AA.
AC   Q14680; A6P3A7; A6P3A8; B1AMQ6; B7Z1E6; B7Z5M5; B7Z6Q7; B7Z6R8;
AC   B7Z6Y0; B7Z7Q1; D3DRP8; F5H0Y0; F5H2R4; F5H689; Q7L3C3;
DE   RecName: Full=Maternal embryonic leucine zipper kinase;
DE            Short=hMELK;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase Eg3;
DE            Short=pEg3 kinase;
DE   AltName: Full=Protein kinase PK38;
DE            Short=hPK38;
DE   AltName: Full=Tyrosine-protein kinase MELK;
DE            EC=2.7.10.2;
GN   Name=MELK; Synonyms=KIAA0175;
DR   GuidetoPHARMACOLOGY; 2102; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
//
ID   MELPH_HUMAN             Reviewed;         600 AA.
AC   Q9BV36; B4DKW7; Q9HA71;
DE   RecName: Full=Melanophilin;
DE   AltName: Full=Exophilin-3;
DE   AltName: Full=Slp homolog lacking C2 domains a;
DE            Short=SlaC2-a;
DE   AltName: Full=Synaptotagmin-like protein 2a;
GN   Name=MLPH; Synonyms=SLAC2A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032400; P:melanosome localization; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
//
ID   MELT_HUMAN              Reviewed;         833 AA.
AC   Q14D04; D3DNL0; F5GZ91; Q2TAA9; Q3MIX2; Q6PEL3; Q86TL5; Q8TCR3;
AC   Q96SP7; Q9C0H1; Q9H9Q7;
DE   RecName: Full=Ventricular zone-expressed PH domain-containing protein homolog 1;
DE   AltName: Full=Protein melted;
GN   Name=VEPH1; Synonyms=KIAA1692, VEPH;
//
ID   MEMO1_HUMAN             Reviewed;         297 AA.
AC   Q9Y316; B4DLS0; D6W575; Q5R2V8; Q5R2V9; Q6NSL5;
DE   RecName: Full=Protein MEMO1;
DE   AltName: Full=C21orf19-like protein;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 7;
DE            Short=HCV NS5A-transactivated protein 7;
DE   AltName: Full=Mediator of ErbB2-driven cell motility 1;
DE            Short=Mediator of cell motility 1;
DE            Short=Memo-1;
GN   Name=MEMO1; Synonyms=C2orf4, MEMO, NS5ATP7; ORFNames=CGI-27;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.
//
ID   MEN1_HUMAN              Reviewed;         615 AA.
AC   O00255; A5HBC6; A5HBC7; A5HBC8; A5HBC9; A5HBD0; A5HBD1; A5HBD2;
AC   O00632; Q9BUF0; Q9BUK2;
DE   RecName: Full=Menin;
GN   Name=MEN1; Synonyms=SCG2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0000400; F:four-way junction DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0034968; P:histone lysine methylation; IDA:GOC.
DR   GO; GO:0001776; P:leukocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IMP:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IGI:MGI.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; IGI:MGI.
DR   GO; GO:0002051; P:osteoblast fate commitment; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0031062; P:positive regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032925; P:regulation of activin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   MENT_HUMAN              Reviewed;         341 AA.
AC   Q9BUN1; B2RDU8; Q9NWZ4;
DE   RecName: Full=Protein MENT;
DE   AltName: Full=Methylated in normal thymocytes protein;
DE   Flags: Precursor;
GN   Name=MENT; Synonyms=C1orf56; ORFNames=UNQ547/PRO1104;
//
ID   MENTO_HUMAN             Reviewed;         234 AA.
AC   O95772; A4D1X0;
DE   RecName: Full=MLN64 N-terminal domain homolog;
DE   AltName: Full=STARD3 N-terminal-like protein;
GN   Name=STARD3NL; Synonyms=MENTHO; ORFNames=UNQ855/PRO1864;
//
ID   MEOX1_HUMAN             Reviewed;         254 AA.
AC   P50221; A8MWF9; Q15069;
DE   RecName: Full=Homeobox protein MOX-1;
DE   AltName: Full=Mesenchyme homeobox 1;
GN   Name=MEOX1; Synonyms=MOX1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001757; P:somite specification; IEA:Ensembl.
//
ID   MEOX2_HUMAN             Reviewed;         304 AA.
AC   P50222; B2R8I7; O75263; Q9UPL6;
DE   RecName: Full=Homeobox protein MOX-2;
DE   AltName: Full=Growth arrest-specific homeobox;
DE   AltName: Full=Mesenchyme homeobox 2;
GN   Name=MEOX2; Synonyms=GAX, MOX2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0060173; P:limb development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0070997; P:neuron death; IMP:UniProt.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0001757; P:somite specification; IEA:Ensembl.
//
ID   MEP1A_HUMAN             Reviewed;         746 AA.
AC   Q16819; A2RRM4; B0AZP9; B2RCS2; Q8TDC9; Q9H1R1;
DE   RecName: Full=Meprin A subunit alpha;
DE            EC=3.4.24.18;
DE   AltName: Full=Endopeptidase-2;
DE   AltName: Full=N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha;
DE   AltName: Full=PABA peptide hydrolase;
DE   AltName: Full=PPH alpha;
DE   Flags: Precursor;
GN   Name=MEP1A;
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
//
ID   MEP1B_HUMAN             Reviewed;         701 AA.
AC   Q16820; B7ZM35; B9EGL6; Q670J1;
DE   RecName: Full=Meprin A subunit beta;
DE            EC=3.4.24.63;
DE   AltName: Full=Endopeptidase-2;
DE   AltName: Full=Meprin B;
DE   AltName: Full=N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta;
DE   AltName: Full=PABA peptide hydrolase;
DE   AltName: Full=PPH beta;
DE   Flags: Precursor;
GN   Name=MEP1B;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
//
ID   MEP50_HUMAN             Reviewed;         342 AA.
AC   Q9BQA1; B3KMW6; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BWY3;
DE   RecName: Full=Methylosome protein 50;
DE            Short=MEP-50;
DE   AltName: Full=Androgen receptor cofactor p44;
DE   AltName: Full=WD repeat-containing protein 77;
DE   AltName: Full=p44/Mep50;
GN   Name=WDR77; Synonyms=MEP50, WD45; ORFNames=HKMT1069, Nbla10071;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IGI:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IEA:Ensembl.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
//
ID   MEPE_HUMAN              Reviewed;         525 AA.
AC   Q9NQ76; A1A4X9; A8MTA3; D2CFR4; F5H5C5;
DE   RecName: Full=Matrix extracellular phosphoglycoprotein;
DE   AltName: Full=Osteoblast/osteocyte factor 45;
DE            Short=OF45;
DE   Flags: Precursor;
GN   Name=MEPE;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0046850; P:regulation of bone remodeling; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   MEPCE_HUMAN             Reviewed;         689 AA.
AC   Q7L2J0; B3KP86; D6W5V7; Q9NPD4;
DE   RecName: Full=7SK snRNA methylphosphate capping enzyme;
DE            Short=MePCE;
DE            EC=2.1.1.-;
DE   AltName: Full=Bicoid-interacting protein 3 homolog;
DE            Short=Bin3 homolog;
GN   Name=MEPCE; Synonyms=BCDIN3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035562; P:negative regulation of chromatin binding; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0001510; P:RNA methylation; IDA:UniProtKB.
DR   GO; GO:0016073; P:snRNA metabolic process; IDA:UniProtKB.
DR   GO; GO:0040031; P:snRNA modification; IDA:UniProtKB.
//
ID   MER34_HUMAN             Reviewed;         563 AA.
AC   Q9H9K5; B3KTB4; Q0P5R3; Q6NWN0;
DE   RecName: Full=HERV-MER_4q12 provirus ancestral Env polyprotein;
DE   AltName: Full=Endogenous retrovirus group MER34 member 1;
DE   Flags: Precursor;
GN   Name=ERVMER34-1; ORFNames=LP9056;
//
ID   MERL_HUMAN              Reviewed;         595 AA.
AC   P35240; O95683; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32;
AC   Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4;
DE   RecName: Full=Merlin;
DE   AltName: Full=Moesin-ezrin-radixin-like protein;
DE   AltName: Full=Neurofibromin-2;
DE   AltName: Full=Schwannomerlin;
DE   AltName: Full=Schwannomin;
GN   Name=NF2; Synonyms=SCH;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:HGNC.
DR   GO; GO:0045216; P:cell-cell junction organization; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; TAS:HGNC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IDA:HGNC.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; TAS:HGNC.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:HGNC.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:HGNC.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; IDA:HGNC.
DR   GO; GO:0042524; P:negative regulation of tyrosine phosphorylation of Stat5 protein; IDA:HGNC.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:HGNC.
DR   GO; GO:0035330; P:regulation of hippo signaling; IMP:UniProtKB.
DR   GO; GO:0014010; P:Schwann cell proliferation; IMP:HGNC.
//
ID   MERTK_HUMAN             Reviewed;         999 AA.
AC   Q12866; Q9HBB4;
DE   RecName: Full=Tyrosine-protein kinase Mer;
DE            EC=2.7.10.1;
DE   AltName: Full=Proto-oncogene c-Mer;
DE   AltName: Full=Receptor tyrosine kinase MerTK;
DE   Flags: Precursor;
GN   Name=MERTK; Synonyms=MER;
DR   GuidetoPHARMACOLOGY; 1837; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0051250; P:negative regulation of lymphocyte activation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0006909; P:phagocytosis; IMP:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0032940; P:secretion by cell; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   MESD1_HUMAN             Reviewed;         362 AA.
AC   Q9H1K6;
DE   RecName: Full=Mesoderm development candidate 1;
GN   Name=MESDC1;
//
ID   MESH1_HUMAN             Reviewed;         179 AA.
AC   Q8N4P3;
DE   RecName: Full=Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1;
DE            EC=3.1.7.2;
DE   AltName: Full=HD domain-containing protein 3;
DE   AltName: Full=Metazoan SpoT homolog 1;
DE            Short=MESH1;
DE   AltName: Full=Penta-phosphate guanosine-3'-pyrophosphohydrolase;
DE            Short=(ppGpp)ase;
GN   Name=HDDC3; Synonyms=MESH1;
DR   GO; GO:0008893; F:guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   MESD_HUMAN              Reviewed;         234 AA.
AC   Q14696; D3DW96; Q969U1;
DE   RecName: Full=LDLR chaperone MESD;
DE   AltName: Full=Mesoderm development candidate 2;
DE   AltName: Full=Mesoderm development protein;
DE   AltName: Full=Renal carcinoma antigen NY-REN-61;
DE   Flags: Precursor;
GN   Name=MESDC2; Synonyms=KIAA0081, MESD; ORFNames=UNQ1911/PRO4369;
DR   GO; GO:0007498; P:mesoderm development; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; ISS:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   MESP2_HUMAN             Reviewed;         397 AA.
AC   Q0VG99; Q7RTU2;
DE   RecName: Full=Mesoderm posterior protein 2;
DE   AltName: Full=Class C basic helix-loop-helix protein 6;
DE            Short=bHLHc6;
GN   Name=MESP2; Synonyms=BHLHC6, SCDO2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008078; P:mesodermal cell migration; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MESP1_HUMAN             Reviewed;         268 AA.
AC   Q9BRJ9; Q9NSF1; Q9NSF2;
DE   RecName: Full=Mesoderm posterior protein 1;
DE   AltName: Full=Class C basic helix-loop-helix protein 5;
DE            Short=bHLHc5;
GN   Name=MESP1; Synonyms=BHLHC5;
DR   GO; GO:0035326; F:enhancer binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003210; P:cardiac atrium formation; IMP:BHF-UCL.
DR   GO; GO:0060913; P:cardiac cell fate determination; ISS:BHF-UCL.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0060947; P:cardiac vascular smooth muscle cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0003211; P:cardiac ventricle formation; IMP:BHF-UCL.
DR   GO; GO:0003259; P:cardioblast anterior-lateral migration; ISS:BHF-UCL.
DR   GO; GO:0060975; P:cardioblast migration to the midline involved in heart field formation; ISS:BHF-UCL.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045446; P:endothelial cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0007369; P:gastrulation; ISS:BHF-UCL.
DR   GO; GO:0003241; P:growth involved in heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0048368; P:lateral mesoderm development; ISS:BHF-UCL.
DR   GO; GO:0008078; P:mesodermal cell migration; IEA:Ensembl.
DR   GO; GO:0042664; P:negative regulation of endodermal cell fate specification; ISS:BHF-UCL.
DR   GO; GO:0042662; P:negative regulation of mesodermal cell fate specification; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0022008; P:neurogenesis; IMP:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0090082; P:positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0070368; P:positive regulation of hepatocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0035481; P:positive regulation of Notch signaling pathway involved in heart induction; IEA:Ensembl.
DR   GO; GO:0051155; P:positive regulation of striated muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0003139; P:secondary heart field specification; ISS:BHF-UCL.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060921; P:sinoatrial node cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0003236; P:sinus venosus morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MEST_HUMAN              Reviewed;         335 AA.
AC   Q5EB52; B2R6S1; O14973; O15007; Q6AI49; Q92571;
DE   RecName: Full=Mesoderm-specific transcript homolog protein;
DE            EC=3.-.-.-;
DE   AltName: Full=Paternally-expressed gene 1 protein;
GN   Name=MEST; Synonyms=PEG1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0010883; P:regulation of lipid storage; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   MET10_HUMAN             Reviewed;         291 AA.
AC   Q5JPI9; A8MPY7;
DE   RecName: Full=Methyltransferase-like protein 10;
DE            EC=2.1.1.-;
GN   Name=METTL10; Synonyms=C10orf138;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET13_HUMAN             Reviewed;         699 AA.
AC   Q8N6R0; A6NFK0; A8K6S5; O94940; Q53EZ6; Q5TGP9; Q5TGQ0; Q8N2P8;
AC   Q96J11; Q96SQ0; Q9Y2Z1; Q9Y3M6;
DE   RecName: Full=Methyltransferase-like protein 13;
DE            EC=2.1.1.-;
GN   Name=METTL13; Synonyms=KIAA0859; ORFNames=CGI-01;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET12_HUMAN             Reviewed;         240 AA.
AC   A8MUP2; B7Z4C1;
DE   RecName: Full=Methyltransferase-like protein 12, mitochondrial;
DE            EC=2.1.1.-;
DE   Flags: Precursor;
GN   Name=METTL12;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET14_HUMAN             Reviewed;         456 AA.
AC   Q9HCE5; A6NIG1; Q969V2;
DE   RecName: Full=N6-adenosine-methyltransferase subunit METTL14;
DE            EC=2.1.1.62;
DE   AltName: Full=Methyltransferase-like protein 14;
GN   Name=METTL14; Synonyms=KIAA1627;
DR   GO; GO:0016422; F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0061157; P:mRNA destabilization; ISS:UniProtKB.
DR   GO; GO:0080009; P:mRNA methylation; IMP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
//
ID   MET15_HUMAN             Reviewed;         407 AA.
AC   A6NJ78; A8MRS5; B7WNU2; Q3MHD3; Q8N601; Q8NBA7;
DE   RecName: Full=Probable methyltransferase-like protein 15;
DE            EC=2.1.1.-;
DE   AltName: Full=Methyltransferase 5 domain-containing protein 1;
GN   Name=METTL15; Synonyms=METT5D1;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET16_HUMAN             Reviewed;         562 AA.
AC   Q86W50; D3DTI8; Q86TE5; Q96T16; Q9BVG7;
DE   RecName: Full=Methyltransferase-like protein 16;
DE            EC=2.1.1.-;
DE   AltName: Full=Methyltransferase 10 domain-containing protein;
GN   Name=METTL16; Synonyms=METT10D;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   MET17_HUMAN             Reviewed;         456 AA.
AC   Q9H7H0; Q9BSH1; Q9BZH2; Q9BZH3;
DE   RecName: Full=Methyltransferase-like protein 17, mitochondrial;
DE            EC=2.1.1.-;
DE   AltName: Full=False p73 target gene protein;
DE   AltName: Full=Methyltransferase 11 domain-containing protein 1;
DE   AltName: Full=Protein RSM22 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=METTL17; Synonyms=METT11D1;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   MET18_HUMAN             Reviewed;         372 AA.
AC   O95568; B2R9T5;
DE   RecName: Full=Histidine protein methyltransferase 1 homolog;
DE            EC=2.1.1.-;
DE   AltName: Full=Arsenic-transactivated protein 2;
DE            Short=AsTP2;
DE   AltName: Full=Methyltransferase-like protein 18;
GN   Name=METTL18; Synonyms=ASTP2, C1orf156;
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
//
ID   MET20_HUMAN             Reviewed;         262 AA.
AC   Q8IXQ9; D3DUW3;
DE   RecName: Full=Methyltransferase-like protein 20;
DE            EC=2.1.1.-;
GN   Name=METTL20; Synonyms=C12orf72;
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
//
ID   MET23_HUMAN             Reviewed;         190 AA.
AC   Q86XA0; H9ZYJ0;
DE   RecName: Full=Methyltransferase-like protein 23;
DE            EC=2.1.1.-;
GN   Name=METTL23; Synonyms=C17orf95;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET22_HUMAN             Reviewed;         404 AA.
AC   Q9BUU2; B2RD29; D3DUF2; Q6XYB4; Q9HA03;
DE   RecName: Full=Methyltransferase-like protein 22;
DE            EC=2.1.1.-;
GN   Name=METTL22; Synonyms=C16orf68; ORFNames=LP8272;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET24_HUMAN             Reviewed;         366 AA.
AC   Q5JXM2; Q6ZSU5;
DE   RecName: Full=Methyltransferase-like protein 24;
DE            EC=2.1.1.-;
DE   Flags: Precursor;
GN   Name=METTL24; Synonyms=C6orf186;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET25_HUMAN             Reviewed;         603 AA.
AC   Q8N6Q8; Q9H5Y3;
DE   RecName: Full=Methyltransferase-like protein 25;
DE            EC=2.1.1.-;
GN   Name=METTL25; Synonyms=C12orf26;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET2A_HUMAN             Reviewed;         378 AA.
AC   Q96IZ6; A6NNC4; Q9H9G9; Q9NUI8; Q9P0B5;
DE   RecName: Full=Methyltransferase-like protein 2A;
DE            EC=2.1.1.-;
GN   Name=METTL2A; Synonyms=METTL2; ORFNames=HSPC266;
DR   GO; GO:0016427; F:tRNA (cytosine) methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0030488; P:tRNA methylation; ISS:UniProtKB.
//
ID   MET2B_HUMAN             Reviewed;         378 AA.
AC   Q6P1Q9; B4DZ68; Q0IJ54; Q3B7J1;
DE   RecName: Full=Methyltransferase-like protein 2B;
DE            EC=2.1.1.-;
GN   Name=METTL2B;
DR   GO; GO:0016427; F:tRNA (cytosine) methyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0030488; P:tRNA methylation; IMP:UniProtKB.
//
ID   MET7A_HUMAN             Reviewed;         244 AA.
AC   Q9H8H3; Q9H7R3; Q9UHZ7; Q9Y422;
DE   RecName: Full=Methyltransferase-like protein 7A;
DE            EC=2.1.1.-;
DE   AltName: Full=Protein AAM-B;
DE   Flags: Precursor;
GN   Name=METTL7A; ORFNames=PRO0066, UNQ1902/PRO4348;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MET7B_HUMAN             Reviewed;         244 AA.
AC   Q6UX53; A8K247; Q8WUI1;
DE   RecName: Full=Methyltransferase-like protein 7B;
DE            EC=2.1.1.-;
DE   Flags: Precursor;
GN   Name=METTL7B; ORFNames=UNQ594/PRO1180;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   METH_HUMAN              Reviewed;        1265 AA.
AC   Q99707; A1L4N8; A9Z1W4; B9EGF7; Q99713; Q99723;
DE   RecName: Full=Methionine synthase;
DE            EC=2.1.1.13;
DE   AltName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase;
DE   AltName: Full=Vitamin-B12 dependent methionine synthase;
DE            Short=MS;
GN   Name=MTR;
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0008898; F:S-adenosylmethionine-homocysteine S-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008705; F:methionine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   METK1_HUMAN             Reviewed;         395 AA.
AC   Q00266; D3DWD5; Q5QP09;
DE   RecName: Full=S-adenosylmethionine synthase isoform type-1;
DE            Short=AdoMet synthase 1;
DE            EC=2.5.1.6;
DE   AltName: Full=Methionine adenosyltransferase 1;
DE            Short=MAT 1;
DE   AltName: Full=Methionine adenosyltransferase I/III;
DE            Short=MAT-I/III;
GN   Name=MAT1A; Synonyms=AMS1, MATA1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004478; F:methionine adenosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006556; P:S-adenosylmethionine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   METK2_HUMAN             Reviewed;         395 AA.
AC   P31153; A8K511; D6W5L1; Q53SP5;
DE   RecName: Full=S-adenosylmethionine synthase isoform type-2;
DE            Short=AdoMet synthase 2;
DE            EC=2.5.1.6;
DE   AltName: Full=Methionine adenosyltransferase 2;
DE            Short=MAT 2;
DE   AltName: Full=Methionine adenosyltransferase II;
DE            Short=MAT-II;
GN   Name=MAT2A; Synonyms=AMS2, MATA2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004478; F:methionine adenosyltransferase activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006556; P:S-adenosylmethionine biosynthetic process; IDA:UniProt.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   METL5_HUMAN             Reviewed;         209 AA.
AC   Q9NRN9; D3DPC9; Q9NVX1;
DE   RecName: Full=Methyltransferase-like protein 5;
DE            EC=2.1.1.-;
GN   Name=METTL5; ORFNames=DC3, HSPC133;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   METL4_HUMAN             Reviewed;         472 AA.
AC   Q8N3J2; B2RNA1; Q2TAA7; Q9H5U9;
DE   RecName: Full=Methyltransferase-like protein 4;
DE            EC=2.1.1.-;
GN   Name=METTL4;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
//
ID   METL8_HUMAN             Reviewed;         291 AA.
AC   Q9H825; Q53TM9; Q53TQ0;
DE   RecName: Full=Methyltransferase-like protein 8;
DE            EC=2.1.1.-;
GN   Name=METTL8;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   METL6_HUMAN             Reviewed;         284 AA.
AC   Q8TCB7; Q96LU4;
DE   RecName: Full=Methyltransferase-like protein 6;
DE            EC=2.1.1.-;
GN   Name=METTL6;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   METL9_HUMAN             Reviewed;         318 AA.
AC   Q9H1A3; Q8NBT8; Q9BWJ7; Q9H1A2; Q9Y390;
DE   RecName: Full=Methyltransferase-like protein 9;
DE   AltName: Full=DORA reverse strand protein;
DE            Short=DREV;
DE   AltName: Full=DREV1;
DE   Flags: Precursor;
GN   Name=METTL9; Synonyms=DREV; ORFNames=CGI-81;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   METRL_HUMAN             Reviewed;         311 AA.
AC   Q641Q3; Q86VM0;
DE   RecName: Full=Meteorin-like protein;
DE   Flags: Precursor;
GN   Name=METRNL;
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProt.
//
ID   METRN_HUMAN             Reviewed;         293 AA.
AC   Q9UJH8; Q9UJH9;
DE   RecName: Full=Meteorin;
DE   Flags: Precursor;
GN   Name=METRN; Synonyms=C16orf23; ORFNames=RJD6;
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
//
ID   MET_HUMAN               Reviewed;        1390 AA.
AC   P08581; A1L467; B5A932; E7EQ94; O60366; Q12875; Q9UDX7; Q9UPL8;
DE   RecName: Full=Hepatocyte growth factor receptor;
DE            Short=HGF receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=HGF/SF receptor;
DE   AltName: Full=Proto-oncogene c-Met;
DE   AltName: Full=Scatter factor receptor;
DE            Short=SF receptor;
DE   AltName: Full=Tyrosine-protein kinase Met;
DE   Flags: Precursor;
GN   Name=MET;
DR   GuidetoPHARMACOLOGY; 1815; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005008; F:hepatocyte growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0014812; P:muscle cell migration; IEA:Ensembl.
DR   GO; GO:0051450; P:myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0014902; P:myotube differentiation; IEA:Ensembl.
DR   GO; GO:1901299; P:negative regulation of hydrogen peroxide-mediated programmed cell death; IMP:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; NAS:GOC.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0010828; P:positive regulation of glucose transport; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0060665; P:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; IEA:Ensembl.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
//
ID   MEX3A_HUMAN             Reviewed;         520 AA.
AC   A1L020;
DE   RecName: Full=RNA-binding protein MEX3A;
DE   AltName: Full=RING finger and KH domain-containing protein 4;
GN   Name=MEX3A; Synonyms=RKHD4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MEX3B_HUMAN             Reviewed;         569 AA.
AC   Q6ZN04; Q4G0W1; Q8IVG2; Q9H0J0;
DE   RecName: Full=RNA-binding protein MEX3B;
DE   AltName: Full=RING finger and KH domain-containing protein 3;
DE   AltName: Full=RING finger protein 195;
GN   Name=MEX3B; Synonyms=KIAA2009, RKHD3, RNF195;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
//
ID   MEX3C_HUMAN             Reviewed;         659 AA.
AC   Q5U5Q3; A1L022; Q9NZE3;
DE   RecName: Full=RNA-binding E3 ubiquitin-protein ligase MEX3C;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger and KH domain-containing protein 2;
DE   AltName: Full=RING finger protein 194;
GN   Name=MEX3C; Synonyms=RKHD2, RNF194; ORFNames=BM-013;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0003415; P:chondrocyte hypertrophy; IEA:Ensembl.
DR   GO; GO:0097009; P:energy homeostasis; IEA:Ensembl.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IEA:Ensembl.
//
ID   MEX3D_HUMAN             Reviewed;         651 AA.
AC   Q86XN8; A0PJL8; A1L023; E9PAL6; Q71M49;
DE   RecName: Full=RNA-binding protein MEX3D;
DE   AltName: Full=RING finger and KH domain-containing protein 1;
DE   AltName: Full=RING finger protein 193;
DE   AltName: Full=TINO;
GN   Name=MEX3D; Synonyms=KIAA2031, RKHD1, RNF193;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0061157; P:mRNA destabilization; NAS:BHF-UCL.
DR   GO; GO:0010609; P:mRNA localization resulting in posttranscriptional regulation of gene expression; NAS:BHF-UCL.
//
ID   MF2L2_HUMAN             Reviewed;        1114 AA.
AC   Q86YR7; O94942; Q6P2B8; Q6ZVJ5; Q8N318;
DE   RecName: Full=Probable guanine nucleotide exchange factor MCF2L2;
DE   AltName: Full=Dbs-related Rho family guanine nucleotide exchange factor;
DE   AltName: Full=MCF2-transforming sequence-like protein 2;
GN   Name=MCF2L2; Synonyms=DRG, KIAA0861;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   MF2NB_HUMAN             Reviewed;         119 AA.
AC   Q96FH0; B2RXF9; Q9BT01;
DE   RecName: Full=Protein MEF2BNB;
DE   AltName: Full=MEF2B neighbor gene protein;
GN   Name=MEF2BNB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007507; P:heart development; IEP:UniProtKB.
//
ID   MFA3L_HUMAN             Reviewed;         409 AA.
AC   O75121; A8K1X6; D3DP35; Q4W5N7; Q4W5N9; Q6TNA8; Q9BVE1; Q9BXK0;
DE   RecName: Full=Microfibrillar-associated protein 3-like;
DE   AltName: Full=Testis development protein NYD-SP9;
DE   Flags: Precursor;
GN   Name=MFAP3L; Synonyms=KIAA0626; ORFNames=HSD-39, HSD39;
//
ID   MFAP1_HUMAN             Reviewed;         439 AA.
AC   P55081; Q86TG6;
DE   RecName: Full=Microfibrillar-associated protein 1;
GN   Name=MFAP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   MFAP2_HUMAN             Reviewed;         183 AA.
AC   P55001; Q53X60; Q5JXY0;
DE   RecName: Full=Microfibrillar-associated protein 2;
DE            Short=MFAP-2;
DE   AltName: Full=Microfibril-associated glycoprotein 1;
DE            Short=MAGP;
DE            Short=MAGP-1;
DE   Flags: Precursor;
GN   Name=MFAP2; Synonyms=MAGP1;
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030220; P:platelet formation; IEA:Ensembl.
//
ID   MFAP3_HUMAN             Reviewed;         362 AA.
AC   P55082; B2RDK0; B4DKA1; Q9NXA7;
DE   RecName: Full=Microfibril-associated glycoprotein 3;
DE   Flags: Precursor;
GN   Name=MFAP3;
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   MFAP4_HUMAN             Reviewed;         255 AA.
AC   P55083; A8KAJ1; A8MVM2; B4E317; Q6P680;
DE   RecName: Full=Microfibril-associated glycoprotein 4;
DE   Flags: Precursor;
GN   Name=MFAP4;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0071493; P:cellular response to UV-B; IDA:BHF-UCL.
DR   GO; GO:0048251; P:elastic fiber assembly; IDA:BHF-UCL.
DR   GO; GO:0043206; P:extracellular fibril organization; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010712; P:regulation of collagen metabolic process; IDA:BHF-UCL.
DR   GO; GO:0009650; P:UV protection; IDA:BHF-UCL.
//
ID   MFAP5_HUMAN             Reviewed;         173 AA.
AC   Q13361; B0AZL6; D3DUV1;
DE   RecName: Full=Microfibrillar-associated protein 5;
DE            Short=MFAP-5;
DE   AltName: Full=MP25;
DE   AltName: Full=Microfibril-associated glycoprotein 2;
DE            Short=MAGP-2;
DE   Flags: Precursor;
GN   Name=MFAP5; Synonyms=MAGP2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0043206; P:extracellular fibril organization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   MFGM_HUMAN              Reviewed;         387 AA.
AC   Q08431; B2R6M7; Q53FU9; Q7Z3D2; Q9BTL9;
DE   RecName: Full=Lactadherin;
DE   AltName: Full=Breast epithelial antigen BA46;
DE   AltName: Full=HMFG;
DE   AltName: Full=MFGM;
DE   AltName: Full=Milk fat globule-EGF factor 8;
DE            Short=MFG-E8;
DE   AltName: Full=SED1;
DE   Contains:
DE     RecName: Full=Lactadherin short form;
DE   Contains:
DE     RecName: Full=Medin;
DE   Flags: Precursor;
GN   Name=MFGE8;
DR   GO; GO:0008429; F:phosphatidylethanolamine binding; IEA:Ensembl.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IEA:Ensembl.
DR   GO; GO:0006910; P:phagocytosis, recognition; IEA:Ensembl.
DR   GO; GO:2000427; P:positive regulation of apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MFF_HUMAN               Reviewed;         342 AA.
AC   Q9GZY8; Q567U1; Q658R6; Q9BVZ1; Q9H690; Q9NRG8;
DE   RecName: Full=Mitochondrial fission factor;
GN   Name=MFF; Synonyms=C2orf33; ORFNames=AD030, AD033, GL004;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; ISS:UniProtKB.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008053; P:mitochondrial fusion; IMP:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:MGI.
DR   GO; GO:0016559; P:peroxisome fission; IMP:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IMP:UniProtKB.
DR   GO; GO:0010821; P:regulation of mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:1900063; P:regulation of peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IMP:UniProtKB.
//
ID   MFHA1_HUMAN             Reviewed;        1052 AA.
AC   Q9Y4C4; Q96CI0;
DE   RecName: Full=Malignant fibrous histiocytoma-amplified sequence 1;
DE   AltName: Full=Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1;
GN   Name=MFHAS1; Synonyms=MASL1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MFN1_HUMAN              Reviewed;         741 AA.
AC   Q8IWA4; B2RAR1; D3DNR6; O15323; O60639; Q9BZB5; Q9NWQ2;
DE   RecName: Full=Mitofusin-1;
DE            EC=3.6.5.-;
DE   AltName: Full=Fzo homolog;
DE   AltName: Full=Transmembrane GTPase MFN1;
GN   Name=MFN1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008053; P:mitochondrial fusion; IMP:UniProtKB.
//
ID   MFN2_HUMAN              Reviewed;         757 AA.
AC   O95140; A8K1B3; O95572; Q5JXC3; Q5JXC4; Q9H131; Q9NSX8;
DE   RecName: Full=Mitofusin-2;
DE            EC=3.6.5.-;
DE   AltName: Full=Transmembrane GTPase MFN2;
GN   Name=MFN2; Synonyms=CPRP1, KIAA0214;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0001825; P:blastocyst formation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0008053; P:mitochondrial fusion; IMP:UniProtKB.
DR   GO; GO:0007006; P:mitochondrial membrane organization; IDA:UniProtKB.
DR   GO; GO:0051646; P:mitochondrion localization; IDA:UniProtKB.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IDA:UniProtKB.
//
ID   MFNG_HUMAN              Reviewed;         321 AA.
AC   O00587; B4DLT6; O43730; Q504S9;
DE   RecName: Full=Beta-1,3-N-acetylglucosaminyltransferase manic fringe;
DE            EC=2.4.1.222;
DE   AltName: Full=O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;
GN   Name=MFNG;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0033829; F:O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007389; P:pattern specification process; TAS:ProtInc.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
//
ID   MFR1L_HUMAN             Reviewed;         292 AA.
AC   Q9H019; A6NCB4; B7WNV5; D3DPJ4; Q63HP1; Q7Z2S7; Q9NUI7;
DE   RecName: Full=Mitochondrial fission regulator 1-like;
GN   Name=MTFR1L; Synonyms=FAM54B; ORFNames=HYST1888, MSTP116;
//
ID   MFRN1_HUMAN             Reviewed;         338 AA.
AC   Q9NYZ2; A2RU93; Q53FT7; Q69YJ8; Q969S1; Q9P0J2;
DE   RecName: Full=Mitoferrin-1;
DE   AltName: Full=Mitochondrial iron transporter 1;
DE   AltName: Full=Mitochondrial solute carrier protein;
DE   AltName: Full=Solute carrier family 25 member 37;
GN   Name=SLC25A37; Synonyms=MFRN, MSCP; ORFNames=HT015;
DR   GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0048250; P:mitochondrial iron ion transport; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MFRN2_HUMAN             Reviewed;         364 AA.
AC   Q96A46; Q4VBZ0; Q5T777; Q86VX5; Q969G8; Q9H2J3;
DE   RecName: Full=Mitoferrin-2;
DE   AltName: Full=Mitochondrial RNA-splicing protein 3/4 homolog;
DE            Short=MRS3/4;
DE            Short=hMRS3/4;
DE   AltName: Full=Mitochondrial iron transporter 2;
DE   AltName: Full=Solute carrier family 25 member 28;
GN   Name=SLC25A28; Synonyms=MFRN2; ORFNames=NPD016;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MFRP_HUMAN              Reviewed;         579 AA.
AC   Q9BY79; B0YJ36; B0YJ37; Q335M3; Q96DQ9;
DE   RecName: Full=Membrane frizzled-related protein;
DE   AltName: Full=Membrane-type frizzled-related protein;
GN   Name=MFRP;
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
//
ID   MFS10_HUMAN             Reviewed;         455 AA.
AC   Q14728; Q07706;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 10;
DE   AltName: Full=Tetracycline transporter-like protein;
GN   Name=MFSD10; Synonyms=TETRAN;
DR   GO; GO:0008493; F:tetracycline transporter activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0015904; P:tetracycline transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MFS11_HUMAN             Reviewed;         449 AA.
AC   O43934; O43442; Q9NXI5;
DE   RecName: Full=UNC93-like protein MFSD11;
DE   AltName: Full=Major facilitator superfamily domain-containing protein 11;
DE   AltName: Full=Protein ET;
GN   Name=MFSD11; Synonyms=ET;
//
ID   MFS12_HUMAN             Reviewed;         480 AA.
AC   Q6NUT3; A8MXP7; D6W615; E9PAJ8; Q8N459;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 12;
GN   Name=MFSD12; Synonyms=C19orf28;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MFS2A_HUMAN             Reviewed;         543 AA.
AC   Q8NA29; A8K675; Q6UWU5; Q96F59; Q9BRC8;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 2A;
GN   Name=MFSD2A; Synonyms=MFSD2; ORFNames=HMFN0656, PP9177, UNQ300/PRO341;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MFS2B_HUMAN             Reviewed;         497 AA.
AC   A6NFX1; B5MC32;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 2B;
GN   Name=MFSD2B;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MFS6L_HUMAN             Reviewed;         586 AA.
AC   Q8IWD5; Q6YL34; Q8NA76;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 6-like;
GN   Name=MFSD6L; ORFNames=FP7072;
//
ID   MFSD1_HUMAN             Reviewed;         465 AA.
AC   Q9H3U5; B4DGJ8; B4DMR8; B4DU49; B4DWU1; C9JS94; J3KQL7; Q05C07;
AC   Q5XKJ1; Q8IVS1; Q8IXG4; Q9H7X1;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 1;
DE   AltName: Full=Smooth muscle cell-associated protein 4;
DE            Short=SMAP-4;
GN   Name=MFSD1; Synonyms=SMAP4; ORFNames=UG0581B09;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFSD3_HUMAN             Reviewed;         412 AA.
AC   Q96ES6;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 3;
GN   Name=MFSD3;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFSD4_HUMAN             Reviewed;         514 AA.
AC   Q8N468; Q6UY25; Q8NAY0; Q8TCP4;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 4;
GN   Name=MFSD4; ORFNames=UNQ3064/PRO9894;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFSD5_HUMAN             Reviewed;         450 AA.
AC   Q6N075; G3V1N7; Q6NW04; Q8N7W8; Q8NCK0; Q96IA5;
DE   RecName: Full=Molybdate-anion transporter;
DE   AltName: Full=Major facilitator superfamily domain-containing protein 5;
DE   AltName: Full=Molybdate transporter 2 homolog;
DE            Short=hsMOT2;
GN   Name=MFSD5; ORFNames=UNQ832/PRO1759;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   MFSD6_HUMAN             Reviewed;         791 AA.
AC   Q6ZSS7; D3KSZ4; Q86TH2; Q9NXM3;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 6;
DE   AltName: Full=Macrophage MHC class I receptor 2 homolog;
GN   Name=MFSD6; Synonyms=MMR2;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFSD7_HUMAN             Reviewed;         560 AA.
AC   Q6UXD7; A8K7J5; Q6XYD4; Q8N6H1; Q9H6H6;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 7;
DE   AltName: Full=Myosin light polypeptide 5 regulatory protein;
DE            Short=MYL5;
GN   Name=MFSD7; ORFNames=LP2561, UNQ385/PRO717;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFSD8_HUMAN             Reviewed;         518 AA.
AC   Q8NHS3; B2RDM1; Q8N2P3;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 8;
DE   AltName: Full=Ceroid-lipofuscinosis neuronal protein 7;
GN   Name=MFSD8; Synonyms=CLN7;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFSD9_HUMAN             Reviewed;         474 AA.
AC   Q8NBP5; Q4ZG89; Q53TU0; Q96GQ4; Q9BRI8;
DE   RecName: Full=Major facilitator superfamily domain-containing protein 9;
GN   Name=MFSD9; ORFNames=PSEC0066;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   MFTC_HUMAN              Reviewed;         315 AA.
AC   Q9H2D1; Q96JZ6; Q96SU7;
DE   RecName: Full=Mitochondrial folate transporter/carrier;
DE   AltName: Full=Solute carrier family 25 member 32;
GN   Name=SLC25A32; Synonyms=MFT, MFTC;
DR   GO; GO:0008517; F:folic acid transporter activity; NAS:UniProtKB.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0015884; P:folic acid transport; NAS:UniProtKB.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MGAL1_HUMAN             Reviewed;         646 AA.
AC   Q6ZN80;
DE   RecName: Full=Putative maltase-glucoamylase-like protein FLJ16351;
DE            EC=3.2.1.-;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   MGAP_HUMAN              Reviewed;        3026 AA.
AC   Q8IWI9; E7ENI0; F5H7K2; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9;
DE   RecName: Full=MAX gene-associated protein;
DE   AltName: Full=MAX dimerization protein 5;
GN   Name=MGA; Synonyms=KIAA0518, MAD5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MGAL2_HUMAN             Reviewed;         482 AA.
AC   Q2M2H8; A4D2I3;
DE   RecName: Full=Putative inactive maltase-glucoamylase-like protein LOC93432;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   MGAT1_HUMAN             Reviewed;         445 AA.
AC   P26572; A8K404; B3KRU8; D3DWR1; Q6IBE3;
DE   RecName: Full=Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase;
DE            EC=2.4.1.101;
DE   AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I;
DE            Short=GNT-I;
DE            Short=GlcNAc-T I;
GN   Name=MGAT1; Synonyms=GGNT1, GLCT1, GLYT1, MGAT;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0003827; F:alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006049; P:UDP-N-acetylglucosamine catabolic process; IEA:Ensembl.
//
ID   MGAT2_HUMAN             Reviewed;         447 AA.
AC   Q10469; B3KPC5;
DE   RecName: Full=Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase;
DE            EC=2.4.1.143;
DE   AltName: Full=Beta-1,2-N-acetylglucosaminyltransferase II;
DE   AltName: Full=GlcNAc-T II;
DE            Short=GNT-II;
DE   AltName: Full=Mannoside acetylglucosaminyltransferase 2;
DE   AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II;
GN   Name=MGAT2;
DR   GO; GO:0008455; F:alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MGAT3_HUMAN             Reviewed;         533 AA.
AC   Q09327; A6NGD0; Q14CK5; Q6IC49; Q9UH32;
DE   RecName: Full=Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase;
DE            EC=2.4.1.144;
DE   AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III;
DE            Short=GNT-III;
DE            Short=GlcNAc-T III;
DE            Short=N-acetylglucosaminyltransferase III;
GN   Name=MGAT3; Synonyms=GGNT3;
DR   GO; GO:0003830; F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MGA_HUMAN               Reviewed;        1857 AA.
AC   O43451; Q0VAX6; Q75ME7; Q86UM5;
DE   RecName: Full=Maltase-glucoamylase, intestinal;
DE   Includes:
DE     RecName: Full=Maltase;
DE              EC=3.2.1.20;
DE     AltName: Full=Alpha-glucosidase;
DE   Includes:
DE     RecName: Full=Glucoamylase;
DE              EC=3.2.1.3;
DE     AltName: Full=Glucan 1,4-alpha-glucosidase;
GN   Name=MGAM; Synonyms=MGA, MGAML;
DR   GO; GO:0004558; F:alpha-glucosidase activity; TAS:Reactome.
DR   GO; GO:0016160; F:amylase activity; IEA:Ensembl.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0004339; F:glucan 1,4-alpha-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032450; F:maltose alpha-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044245; P:polysaccharide digestion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0005983; P:starch catabolic process; TAS:ProtInc.
//
ID   MGDP1_HUMAN             Reviewed;         176 AA.
AC   Q86V88; Q86Y84; Q8NAD9;
DE   RecName: Full=Magnesium-dependent phosphatase 1;
DE            Short=MDP-1;
DE            EC=3.1.3.-;
DE            EC=3.1.3.48;
GN   Name=MDP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
//
ID   MGLL_HUMAN              Reviewed;         303 AA.
AC   Q99685; B3KRC2; B7Z9D1; Q6IBG9; Q96AA5;
DE   RecName: Full=Monoglyceride lipase;
DE            Short=MGL;
DE            EC=3.1.1.23;
DE   AltName: Full=HU-K5;
DE   AltName: Full=Lysophospholipase homolog;
DE   AltName: Full=Lysophospholipase-like;
DE   AltName: Full=Monoacylglycerol lipase;
DE            Short=MAGL;
GN   Name=MGLL;
DR   GuidetoPHARMACOLOGY; 1399; -.
DR   GO; GO:0047372; F:acylglycerol lipase activity; ISS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:Ensembl.
DR   GO; GO:0004622; F:lysophospholipase activity; TAS:ProtInc.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0036155; P:acylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0046464; P:acylglycerol catabolic process; ISS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:2000124; P:regulation of endocannabinoid signaling pathway; ISS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   MGME1_HUMAN             Reviewed;         344 AA.
AC   Q9BQP7; B2RDG5; D3DW29; Q96SW3;
DE   RecName: Full=Mitochondrial genome maintenance exonuclease 1;
DE            EC=3.1.-.-;
DE   Flags: Precursor;
GN   Name=MGME1; Synonyms=C20orf72, DDK1;
DR   GO; GO:0008297; F:single-stranded DNA exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:GOC.
DR   GO; GO:0043504; P:mitochondrial DNA repair; TAS:UniProtKB.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IMP:UniProtKB.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IMP:UniProtKB.
//
ID   MGMT_HUMAN              Reviewed;         207 AA.
AC   P16455; Q5VY78;
DE   RecName: Full=Methylated-DNA--protein-cysteine methyltransferase;
DE            EC=2.1.1.63;
DE   AltName: Full=6-O-methylguanine-DNA methyltransferase;
DE            Short=MGMT;
DE   AltName: Full=O-6-methylguanine-DNA-alkyltransferase;
GN   Name=MGMT;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0009008; F:DNA-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0003908; F:methylated-DNA-[protein]-cysteine S-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008168; F:methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0006307; P:DNA dealkylation involved in DNA repair; IEA:Ensembl.
DR   GO; GO:0006266; P:DNA ligation; TAS:ProtInc.
DR   GO; GO:0006306; P:DNA methylation; TAS:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IEA:Ensembl.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
//
ID   MGN2_HUMAN              Reviewed;         148 AA.
AC   Q96A72;
DE   RecName: Full=Protein mago nashi homolog 2;
GN   Name=MAGOHB; Synonyms=MAGOH2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   MGN_HUMAN               Reviewed;         146 AA.
AC   P61326; B2R5A2; O35169; P50606; Q5SW69;
DE   RecName: Full=Protein mago nashi homolog;
GN   Name=MAGOH; Synonyms=MAGOHA;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   MGP_HUMAN               Reviewed;         103 AA.
AC   P08493; A0M8W5; B2R519; J3KMX7; Q2TU41; Q567P9; Q6ICN5;
DE   RecName: Full=Matrix Gla protein;
DE            Short=MGP;
DE   AltName: Full=Cell growth-inhibiting gene 36 protein;
DE   Flags: Precursor;
GN   Name=MGP; Synonyms=MGLAP; ORFNames=GIG36;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0008147; F:structural constituent of bone; TAS:ProtInc.
DR   GO; GO:0001502; P:cartilage condensation; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:InterPro.
//
ID   MGRN1_HUMAN             Reviewed;         552 AA.
AC   O60291; A4URL3; A4URL4; Q86W76;
DE   RecName: Full=E3 ubiquitin-protein ligase MGRN1;
DE            EC=6.3.2.-;
DE   AltName: Full=Mahogunin RING finger protein 1;
DE   AltName: Full=RING finger protein 156;
GN   Name=MGRN1; Synonyms=KIAA0544, RNF156;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
//
ID   MGST1_HUMAN             Reviewed;         155 AA.
AC   P10620; A8K533; G5EA53;
DE   RecName: Full=Microsomal glutathione S-transferase 1;
DE            Short=Microsomal GST-1;
DE            EC=2.5.1.18;
DE   AltName: Full=Microsomal GST-I;
GN   Name=MGST1; Synonyms=GST12, MGST;
DR   GO; GO:0043295; F:glutathione binding; IEA:Ensembl.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071449; P:cellular response to lipid hydroperoxide; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   MGST2_HUMAN             Reviewed;         147 AA.
AC   Q99735; D6RBB5; Q7Z5B8;
DE   RecName: Full=Microsomal glutathione S-transferase 2;
DE            Short=Microsomal GST-2;
DE            EC=2.5.1.18;
DE   AltName: Full=Microsomal GST-II;
GN   Name=MGST2; Synonyms=GST2;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IBA:RefGenome.
DR   GO; GO:0004364; F:glutathione transferase activity; IDA:UniProtKB.
DR   GO; GO:0004464; F:leukotriene-C4 synthase activity; IDA:UniProtKB.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IDA:UniProtKB.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IBA:GOC.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   MGST3_HUMAN             Reviewed;         152 AA.
AC   O14880; B2R592; Q6ICN4;
DE   RecName: Full=Microsomal glutathione S-transferase 3;
DE            Short=Microsomal GST-3;
DE            EC=2.5.1.18;
DE   AltName: Full=Microsomal GST-III;
GN   Name=MGST3;
DR   GO; GO:0004602; F:glutathione peroxidase activity; IBA:RefGenome.
DR   GO; GO:0004364; F:glutathione transferase activity; IBA:RefGenome.
DR   GO; GO:0004601; F:peroxidase activity; TAS:ProtInc.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0055114; P:oxidation-reduction process; IBA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   MGT4A_HUMAN             Reviewed;         535 AA.
AC   Q9UM21; B4E2R6; D3DVH6; E9PEN2; Q53S97; Q86Z15;
DE   RecName: Full=Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A;
DE            EC=2.4.1.145;
DE   AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa;
DE            Short=GlcNAc-T IVa;
DE            Short=GnT-IVa;
DE            Short=N-acetylglucosaminyltransferase IVa;
DE   AltName: Full=UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa;
DE   Contains:
DE     RecName: Full=Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form;
GN   Name=MGAT4A;
DR   GO; GO:0008454; F:alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006491; P:N-glycan processing; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MGT4B_HUMAN             Reviewed;         548 AA.
AC   Q9UQ53; A8MPR0; Q86TF1; Q96GH4; Q9NSK6;
DE   RecName: Full=Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B;
DE            EC=2.4.1.145;
DE   AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb;
DE            Short=GlcNAc-T IVb;
DE            Short=GnT-IVb;
DE            Short=N-acetylglucosaminyltransferase IVb;
DE   AltName: Full=UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb;
GN   Name=MGAT4B; ORFNames=UNQ906/PRO1927;
DR   GO; GO:0008454; F:alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006491; P:N-glycan processing; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MGT4C_HUMAN             Reviewed;         478 AA.
AC   Q9UBM8; Q4G199; Q9UIU5;
DE   RecName: Full=Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C;
DE            EC=2.4.1.145;
DE   AltName: Full=N-acetylglucosaminyltransferase IV homolog;
DE            Short=hGnT-IV-H;
DE   AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVc;
DE            Short=GlcNAc-T IVc;
DE            Short=GnT-IVc;
DE            Short=N-acetylglucosaminyltransferase IVc;
DE   AltName: Full=UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVc;
GN   Name=MGAT4C;
DR   GO; GO:0008454; F:alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MGT4L_HUMAN             Reviewed;         205 AA.
AC   Q49AQ9;
DE   RecName: Full=Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515;
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   MGT5A_HUMAN             Reviewed;         741 AA.
AC   Q09328; D3DP70;
DE   RecName: Full=Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A;
DE            EC=2.4.1.155;
DE   AltName: Full=Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase;
DE   AltName: Full=GlcNAc-T V;
DE            Short=GNT-V;
DE   AltName: Full=Mannoside acetylglucosaminyltransferase 5;
DE   AltName: Full=N-acetylglucosaminyl-transferase V;
GN   Name=MGAT5; Synonyms=GGNT5;
DR   GO; GO:0030144; F:alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MGT5B_HUMAN             Reviewed;         792 AA.
AC   Q3V5L5; Q6P3S8; Q6P6B3; Q766X5; Q76D04; Q96LS2;
DE   RecName: Full=Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B;
DE            EC=2.4.1.-;
DE            EC=2.4.1.155;
DE   AltName: Full=Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B;
DE   AltName: Full=GlcNAc-T Vb;
DE            Short=GNT-Vb;
DE            Short=hGnTVb;
DE   AltName: Full=Mannoside acetylglucosaminyltransferase 5B;
DE   AltName: Full=N-acetylglucosaminyl-transferase Vb;
DE   AltName: Full=N-acetylglucosaminyltransferase IX;
DE            Short=GNT-IX;
GN   Name=MGAT5B; Synonyms=KIAA2008;
DR   GO; GO:0030144; F:alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IEA:InterPro.
//
ID   MI4GD_HUMAN             Reviewed;         222 AA.
AC   A9UHW6; B4DUM7; Q8N4Q5; Q9HBL5;
DE   RecName: Full=MIF4G domain-containing protein;
DE   AltName: Full=SLBP-interacting protein 1;
DE            Short=hSLIP1;
GN   Name=MIF4GD; Synonyms=SLIP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   MIA2_HUMAN              Reviewed;         542 AA.
AC   Q96PC5; A1L4H0; Q9H6C1;
DE   RecName: Full=Melanoma inhibitory activity protein 2;
DE   Flags: Precursor;
GN   Name=MIA2;
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0070328; P:triglyceride homeostasis; IEA:Ensembl.
//
ID   MIA3_HUMAN              Reviewed;        1907 AA.
AC   Q5JRA6; A8K2S0; A8MT05; A8MT13; B7Z430; Q14083; Q3S4X3; Q5JRA5;
AC   Q5JRB0; Q5JRB1; Q5JRB2; Q6UVY8; Q86Y60; Q8N8M5; Q92580;
DE   RecName: Full=Melanoma inhibitory activity protein 3;
DE   AltName: Full=C219-reactive peptide;
DE   AltName: Full=D320;
DE   AltName: Full=Transport and Golgi organization protein 1;
DE   Flags: Precursor;
GN   Name=MIA3; Synonyms=KIAA0268, TANGO, TANGO1;
GN   ORFNames=UNQ6077/PRO20088;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IMP:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IDA:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IDA:BHF-UCL.
//
ID   MIA40_HUMAN             Reviewed;         142 AA.
AC   Q8N4Q1; A8K3Z9; Q96AI2; Q96MY6;
DE   RecName: Full=Mitochondrial intermembrane space import and assembly protein 40;
DE   AltName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 4;
GN   Name=CHCHD4; Synonyms=MIA40;
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IMP:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0045041; P:protein import into mitochondrial intermembrane space; IMP:UniProtKB.
DR   GO; GO:0022417; P:protein maturation by protein folding; IMP:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   MIA_HUMAN               Reviewed;         131 AA.
AC   Q16674; Q6FHV3;
DE   RecName: Full=Melanoma-derived growth regulatory protein;
DE   AltName: Full=Melanoma inhibitory activity protein;
DE   Flags: Precursor;
GN   Name=MIA;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
//
ID   MIB1_HUMAN              Reviewed;        1006 AA.
AC   Q86YT6; B0YJ38; Q2TB37; Q68D01; Q6YI51; Q8NBY0; Q8TCB5; Q8TCL7;
AC   Q9P2M3;
DE   RecName: Full=E3 ubiquitin-protein ligase MIB1;
DE            EC=6.3.2.-;
DE   AltName: Full=DAPK-interacting protein 1;
DE            Short=DIP-1;
DE   AltName: Full=Mind bomb homolog 1;
DE   AltName: Full=Zinc finger ZZ type with ankyrin repeat domain protein 2;
GN   Name=MIB1; Synonyms=DIP1, KIAA1323, ZZANK2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   MIB2_HUMAN              Reviewed;        1013 AA.
AC   Q96AX9; A2AGM5; A2AGM6; B3KV93; B3KVF4; B3KXY1; B4DZ57; E9PGU1;
AC   E9PHQ1; F8WA73; J3KNZ7; Q7Z437; Q8IY62; Q8N786; Q8N897; Q8N8R2;
AC   Q8N911; Q8NB36; Q8NCY1; Q8NG59; Q8NG60; Q8NG61; Q8NI59; Q8WYN1;
DE   RecName: Full=E3 ubiquitin-protein ligase MIB2;
DE            EC=6.3.2.-;
DE   AltName: Full=Mind bomb homolog 2;
DE   AltName: Full=Novel zinc finger protein;
DE            Short=Novelzin;
DE   AltName: Full=Putative NF-kappa-B-activating protein 002N;
DE   AltName: Full=Skeletrophin;
DE   AltName: Full=Zinc finger ZZ type with ankyrin repeat domain protein 1;
GN   Name=MIB2; Synonyms=SKD, ZZANK1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
//
ID   MIC1_HUMAN              Reviewed;         657 AA.
AC   Q96DM3; Q9BU17; Q9Y5M0;
DE   RecName: Full=Uncharacterized protein C18orf8;
DE   AltName: Full=Colon cancer-associated protein Mic1;
DE            Short=Mic-1;
GN   Name=C18orf8; Synonyms=MIC1;
//
ID   MICA1_HUMAN             Reviewed;        1067 AA.
AC   Q8TDZ2; B7Z3R5; E1P5F0; Q7Z633; Q8IVS9; Q96G47; Q9H6X6; Q9H7I0;
AC   Q9HAA1; Q9UFF7;
DE   RecName: Full=Protein-methionine sulfoxide oxidase MICAL1;
DE            EC=1.14.13.-;
DE   AltName: Full=Molecule interacting with CasL protein 1;
DE            Short=MICAL-1;
DE   AltName: Full=NEDD9-interacting protein with calponin homology and LIM domains;
GN   Name=MICAL1; Synonyms=MICAL, NICAL;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0071949; F:FAD binding; IDA:UniProtKB.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030042; P:actin filament depolymerization; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0019417; P:sulfur oxidation; ISS:UniProtKB.
//
ID   MICA2_HUMAN             Reviewed;        1124 AA.
AC   O94851; B4DGZ0; B7Z849; D3DQW5; G3XAC8; Q5KTR3; Q5KTR4; Q7Z3A8;
DE   RecName: Full=Protein-methionine sulfoxide oxidase MICAL2;
DE            EC=1.14.13.-;
DE   AltName: Full=Molecule interacting with CasL protein 2;
DE            Short=MICAL-2;
GN   Name=MICAL2; Synonyms=KIAA0750, MICAL2PV1, MICAL2PV2;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0071949; F:FAD binding; ISS:UniProtKB.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:UniProtKB.
DR   GO; GO:0019417; P:sulfur oxidation; ISS:UniProtKB.
//
ID   MICA3_HUMAN             Reviewed;        2002 AA.
AC   Q7RTP6; B2RXJ5; E9PEF0; O94909; Q5U4P4; Q6ICK4; Q96DF2; Q9P2I3;
DE   RecName: Full=Protein-methionine sulfoxide oxidase MICAL3;
DE            EC=1.14.13.-;
DE   AltName: Full=Molecule interacting with CasL protein 3;
DE            Short=MICAL-3;
GN   Name=MICAL3; Synonyms=KIAA0819, KIAA1364;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0071949; F:FAD binding; ISS:UniProtKB.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030042; P:actin filament depolymerization; ISS:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:UniProtKB.
//
ID   MICA_HUMAN              Reviewed;         383 AA.
AC   Q29983; A8KQR0; A9LRW5; A9QVE0; B1VJF1; O60917; O60918; O60919;
AC   O60920; O60933; O77956; O78150; O78151; O78152; O78153; O97987;
AC   O97988; O97989; O97990; O97991; O97992; O97993; O97994; O97995;
AC   O98234; O98235; O98236; O98237; O98238; P79506; P79507; P79508;
AC   P79509; P79510; P79511; P79512; P79513; P79514; P79515; P79516;
AC   P79517; P79518; P79519; P79520; P79521; Q5C9P8; Q5XM81; Q70I48;
AC   Q70I49; Q7JFH9; Q7JFI0; Q7JFI1; Q7JFI2; Q7YQ98; Q861I1; Q95464;
AC   Q95HA2; Q95HD6; Q95HN4; Q95HN5; Q95HN6; Q95IB2; Q95IY7; Q99692;
AC   Q9BCR3; Q9BCR4; Q9BCR5; Q9BCR6; Q9BCR7; Q9BCR8; Q9BCR9; Q9BCS0;
AC   Q9BCS1; Q9BCS2; Q9BCS3; Q9BCS4; Q9BD20; Q9GIZ1; Q9GIZ2; Q9GIZ3;
AC   Q9GIZ4; Q9GIZ5; Q9GIZ6; Q9GJ01; Q9GJ02; Q9GJ03; Q9GJ04; Q9GJ05;
AC   Q9GJ06; Q9GJ07; Q9GJ08; Q9GJ09; Q9MY21; Q9TQ86; Q9TQ87; Q9TQ88;
AC   Q9TQ89; Q9TQ92; Q9TQ93; Q9TQ94; Q9TQ95; Q9TQ96; Q9TQ97; Q9TQ98;
AC   Q9TQ99; Q9TQA0; Q9TQA1; Q9TQA2; Q9TQA3; Q9TQA4; Q9TQI9; Q9TQJ0;
AC   Q9TQJ1; Q9TQJ9; Q9TQK0; Q9TQK1; Q9TQK2; Q9TQK8; Q9TQK9; Q9TQL0;
AC   Q9TQL1; Q9TQL2; Q9TQL3; Q9TQL4; Q9UE04; Q9UE05; Q9UE06; Q9UE11;
DE   RecName: Full=MHC class I polypeptide-related sequence A;
DE            Short=MIC-A;
DE   Flags: Precursor;
GN   Name=MICA; Synonyms=PERB11.1;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0046629; P:gamma-delta T cell activation; IDA:UniProtKB.
DR   GO; GO:0002418; P:immune response to tumor cell; IDA:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0009408; P:response to heat; IDA:UniProtKB.
DR   GO; GO:0001913; P:T cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MICB_HUMAN              Reviewed;         383 AA.
AC   Q29980; A6NP85; B0UZ10; O14499; O14500; O19798; O19799; O19800;
AC   O19801; O19802; O19803; O78099; O78100; O78101; O78102; O78103;
AC   O78104; P79525; P79541; Q5GR31; Q5GR37; Q5GR41; Q5GR42; Q5GR43;
AC   Q5GR44; Q5GR46; Q5GR48; Q5RIY6; Q5SSK1; Q5ST25; Q7JK51; Q7YQ89;
AC   Q9MY18; Q9MY19; Q9MY20; Q9UBH4; Q9UBZ8; Q9UEJ0;
DE   RecName: Full=MHC class I polypeptide-related sequence B;
DE            Short=MIC-B;
DE   Flags: Precursor;
GN   Name=MICB; Synonyms=PERB11.2;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IDA:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0046629; P:gamma-delta T cell activation; IDA:UniProtKB.
DR   GO; GO:0002429; P:immune response-activating cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IBA:RefGenome.
DR   GO; GO:0050689; P:negative regulation of defense response to virus by host; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0009408; P:response to heat; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0001913; P:T cell mediated cytotoxicity; IBA:RefGenome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MICLK_HUMAN             Reviewed;         695 AA.
AC   Q6ZW33; Q7RTP7; Q96JU6;
DE   RecName: Full=MICAL C-terminal-like protein;
DE   AltName: Full=ERK2-binding testicular protein 1;
DE   AltName: Full=Ebitein-1;
GN   Name=MICALCL;
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   MICU1_HUMAN             Reviewed;         476 AA.
AC   Q9BPX6; A8MV96; B3KN20; B4DJH9; B4DPI1; B5MBY3; D3YTJ3; O75785;
AC   Q9H9N6; Q9UFX0;
DE   RecName: Full=Calcium uptake protein 1, mitochondrial;
DE   AltName: Full=Atopy-related autoantigen CALC;
DE            Short=ara CALC;
DE   AltName: Full=Calcium-binding atopy-related autoantigen 1;
DE   AltName: Allergen=Hom s 4;
GN   Name=MICU1; Synonyms=CALC, CBARA1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0070509; P:calcium ion import; IDA:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0051560; P:mitochondrial calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   MICU2_HUMAN             Reviewed;         434 AA.
AC   Q8IYU8; Q8N0T6; Q8NAX8;
DE   RecName: Full=Calcium uptake protein 2, mitochondrial;
DE   AltName: Full=EF-hand domain-containing family member A1;
DE   Flags: Precursor;
GN   Name=MICU2; Synonyms=EFHA1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0051562; P:negative regulation of mitochondrial calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0051561; P:positive regulation of mitochondrial calcium ion concentration; IEA:Ensembl.
//
ID   MICU3_HUMAN             Reviewed;         530 AA.
AC   Q86XE3; Q8IYZ3;
DE   RecName: Full=Calcium uptake protein 3, mitochondrial;
DE   AltName: Full=EF-hand domain-containing family member A2;
GN   Name=MICU3; Synonyms=EFHA2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   MID49_HUMAN             Reviewed;         454 AA.
AC   Q96C03; J3KPT3; Q6ZRD4; Q96N07;
DE   RecName: Full=Mitochondrial dynamics protein MID49;
DE   AltName: Full=Mitochondrial dynamics protein of 49 kDa;
DE   AltName: Full=Mitochondrial elongation factor 2;
DE   AltName: Full=Smith-Magenis syndrome chromosomal region candidate gene 7 protein;
GN   Name=MIEF2; Synonyms=MID49, SMCR7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; IDA:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IDA:UniProtKB.
//
ID   MID51_HUMAN             Reviewed;         463 AA.
AC   Q9NQG6; Q9BUI3;
DE   RecName: Full=Mitochondrial dynamics protein MID51;
DE   AltName: Full=Mitochondrial dynamics protein of 51 kDa;
DE   AltName: Full=Mitochondrial elongation factor 1;
DE   AltName: Full=Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like;
DE            Short=SMCR7-like protein;
GN   Name=MIEF1; Synonyms=MID51, SMCR7L;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; IMP:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IDA:UniProtKB.
//
ID   MIDN_HUMAN              Reviewed;         468 AA.
AC   Q504T8; Q96BW8;
DE   RecName: Full=Midnolin;
DE   AltName: Full=Midbrain nucleolar protein;
GN   Name=MIDN;
//
ID   MIEAP_HUMAN             Reviewed;         538 AA.
AC   Q8TC71; B4E2R0; E5RLK1; Q8IY48; Q8N7D7;
DE   RecName: Full=Mitochondria-eating protein;
DE   AltName: Full=Spermatogenesis-associated protein 18;
GN   Name=SPATA18; Synonyms=MIEAP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0035694; P:mitochondrial protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0035695; P:mitochondrion degradation by induced vacuole formation; IMP:UniProtKB.
//
ID   MIEN1_HUMAN             Reviewed;         115 AA.
AC   Q9BRT3;
DE   RecName: Full=Migration and invasion enhancer 1;
DE   AltName: Full=HBV X-transactivated gene 4 protein;
DE   AltName: Full=HBV XAg-transactivated protein 4;
DE   AltName: Full=Protein C35;
DE   Flags: Precursor;
GN   Name=MIEN1; Synonyms=C17orf37, RDX12, XTP4;
DR   GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IDA:UniProtKB.
//
ID   MIER1_HUMAN             Reviewed;         512 AA.
AC   Q8N108; C9JFD4; Q08AE0; Q32NC4; Q5T104; Q5TAD2; Q5TAD4; Q5TAD5;
AC   Q6AHY8; Q86TB4; Q8N156; Q8N161; Q8NC37; Q8NES4; Q8NES5; Q8NES6;
AC   Q8WWG2; Q9HCG2;
DE   RecName: Full=Mesoderm induction early response protein 1;
DE            Short=Early response 1;
DE            Short=Er1;
DE            Short=Mi-er1;
DE            Short=hMi-er1;
GN   Name=MIER1; Synonyms=KIAA1610;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0031937; P:positive regulation of chromatin silencing; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MIER2_HUMAN             Reviewed;         545 AA.
AC   Q8N344; Q9ULM7;
DE   RecName: Full=Mesoderm induction early response protein 2;
DE            Short=Mi-er2;
GN   Name=MIER2; Synonyms=KIAA1193;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MIER3_HUMAN             Reviewed;         550 AA.
AC   Q7Z3K6; B4DRI9; B8ZZQ0; Q5CZI0; Q68CS3; Q6MZS7; Q86YG8; Q8NA13;
DE   RecName: Full=Mesoderm induction early response protein 3;
DE            Short=Mi-er3;
GN   Name=MIER3;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MIF_HUMAN               Reviewed;         115 AA.
AC   P14174; A5Z1R8; B2R4S3; Q2V4Y5; Q6FHV0;
DE   RecName: Full=Macrophage migration inhibitory factor;
DE            Short=MIF;
DE            EC=5.3.2.1;
DE   AltName: Full=Glycosylation-inhibiting factor;
DE            Short=GIF;
DE   AltName: Full=L-dopachrome isomerase;
DE   AltName: Full=L-dopachrome tautomerase;
DE            EC=5.3.3.12;
DE   AltName: Full=Phenylpyruvate tautomerase;
GN   Name=MIF; Synonyms=GLIF, MMIF;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.
DR   GO; GO:0005125; F:cytokine activity; IDA:UniProtKB.
DR   GO; GO:0005126; F:cytokine receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004167; F:dopachrome isomerase activity; IDA:UniProtKB.
DR   GO; GO:0050178; F:phenylpyruvate tautomerase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090344; P:negative regulation of cell aging; IDA:BHF-UCL.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0032269; P:negative regulation of cellular protein metabolic process; IEA:Ensembl.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0002906; P:negative regulation of mature B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0033033; P:negative regulation of myeloid cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0090238; P:positive regulation of arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000343; P:positive regulation of chemokine (C-X-C motif) ligand 2 production; IEA:Ensembl.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0061081; P:positive regulation of myeloid leukocyte cytokine production involved in immune response; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0061078; P:positive regulation of prostaglandin secretion involved in immune response; IEA:Ensembl.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; IDA:BHF-UCL.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; IPI:UniProtKB.
DR   GO; GO:0043030; P:regulation of macrophage activation; NAS:UniProtKB.
//
ID   MIIP_HUMAN              Reviewed;         388 AA.
AC   Q5JXC2; C0KL22; Q96HU6; Q9H839; Q9HA00;
DE   RecName: Full=Migration and invasion-inhibitory protein;
DE   AltName: Full=IGFBP2-binding protein;
DE   AltName: Full=Invasion-inhibitory protein 45;
DE            Short=IIp45;
GN   Name=MIIP; Synonyms=IIP45;
//
ID   MILK1_HUMAN             Reviewed;         863 AA.
AC   Q8N3F8; Q5TI16; Q7RTP5; Q8N3N8; Q9BVL9; Q9BY92; Q9UH43; Q9UH44;
AC   Q9UH45;
DE   RecName: Full=MICAL-like protein 1;
DE   AltName: Full=Molecule interacting with Rab13;
DE            Short=MIRab13;
GN   Name=MICALL1; Synonyms=KIAA1668, MIRAB13;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0097320; P:membrane tubulation; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0036010; P:protein localization to endosome; IMP:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:1990126; P:retrograde transport, endosome to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0032458; P:slow endocytic recycling; IMP:UniProtKB.
//
ID   MILK2_HUMAN             Reviewed;         904 AA.
AC   Q8IY33; D3YTD2; Q7RTP4; Q7Z655; Q8TEQ4; Q9H5F9;
DE   RecName: Full=MICAL-like protein 2;
DE   AltName: Full=Junctional Rab13-binding protein;
DE   AltName: Full=Molecule interacting with CasL-like 2;
DE            Short=MICAL-L2;
GN   Name=MICALL2; Synonyms=JRAB;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0031005; F:filamin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; ISS:UniProtKB.
//
ID   MILR1_HUMAN             Reviewed;         343 AA.
AC   Q7Z6M3; A1L458; B4DUS1; B7ZM50; B9EGN0; D6RUW6; D6RUW8;
DE   RecName: Full=Allergin-1;
DE   AltName: Full=Allergy inhibitory receptor 1;
DE   AltName: Full=Mast cell antigen 32;
DE            Short=MCA-32;
DE   AltName: Full=Mast cell immunoglobulin-like receptor 1;
DE   Flags: Precursor;
GN   Name=MILR1; Synonyms=C17orf60, MCA32;
DR   GO; GO:0043303; P:mast cell degranulation; ISS:UniProtKB.
DR   GO; GO:0033004; P:negative regulation of mast cell activation; ISS:UniProtKB.
//
ID   MIME_HUMAN              Reviewed;         298 AA.
AC   P20774; Q6FIB0; Q9UF90; Q9UNK5;
DE   RecName: Full=Mimecan;
DE   AltName: Full=Osteoglycin;
DE   AltName: Full=Osteoinductive factor;
DE            Short=OIF;
DE   Flags: Precursor;
GN   Name=OGN; Synonyms=OIF, SLRR3A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MIMIT_HUMAN             Reviewed;         169 AA.
AC   Q8N183; A8K5I1;
DE   RecName: Full=Mimitin, mitochondrial;
DE   AltName: Full=B17.2-like;
DE            Short=B17.2L;
DE   AltName: Full=Myc-induced mitochondrial protein;
DE            Short=MMTN;
DE   AltName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2;
DE   AltName: Full=NDUFA12-like protein;
DE   Flags: Precursor;
GN   Name=NDUFAF2; Synonyms=NDUFA12L;
DR   GO; GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
//
ID   MINA_HUMAN              Reviewed;         465 AA.
AC   Q8IUF8; D3DN35; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q96C17;
AC   Q96KB0;
DE   RecName: Full=Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA;
DE            EC=1.14.11.-;
DE   AltName: Full=60S ribosomal protein L27a histidine hydroxylase;
DE   AltName: Full=Histone lysine demethylase MINA;
DE   AltName: Full=MYC-induced nuclear antigen;
DE   AltName: Full=Mineral dust-induced gene protein;
DE   AltName: Full=Nucleolar protein 52;
DE   AltName: Full=Ribosomal oxygenase MINA;
DE            Short=ROX;
GN   Name=MINA; Synonyms=MDIG, MINA53, NO52;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   MINK1_HUMAN             Reviewed;        1332 AA.
AC   Q8N4C8; D3DTK3; D3DTK4; Q5U8Z0; Q9P1X1; Q9P2R8;
DE   RecName: Full=Misshapen-like kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=GCK family kinase MiNK;
DE   AltName: Full=MAPK/ERK kinase kinase kinase 6;
DE            Short=MEK kinase kinase 6;
DE            Short=MEKKK 6;
DE   AltName: Full=Misshapen/NIK-related kinase;
DE   AltName: Full=Mitogen-activated protein kinase kinase kinase kinase 6;
GN   Name=MINK1; Synonyms=B55, MAP4K6, MINK, YSK2, ZC3;
DR   GuidetoPHARMACOLOGY; 2103; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; ISS:UniProtKB.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0006950; P:response to stress; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; ISS:UniProtKB.
//
ID   MINP1_HUMAN             Reviewed;         487 AA.
AC   Q9UNW1; F5H683; O95172; O95286; Q59EJ2; Q9UGA3;
DE   RecName: Full=Multiple inositol polyphosphate phosphatase 1;
DE            EC=3.1.3.62;
DE   AltName: Full=2,3-bisphosphoglycerate 3-phosphatase;
DE            Short=2,3-BPG phosphatase;
DE            EC=3.1.3.80;
DE   AltName: Full=Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase;
DE            Short=Ins(1,3,4,5)P(4) 3-phosphatase;
DE   Flags: Precursor;
GN   Name=MINPP1; Synonyms=MIPP; ORFNames=UNQ900/PRO1917;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR   GO; GO:0034417; F:bisphosphoglycerate 3-phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0052826; F:inositol hexakisphosphate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008969; F:phosphohistidine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0030282; P:bone mineralization; NAS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; NAS:UniProtKB.
DR   GO; GO:0006797; P:polyphosphate metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MINT_HUMAN              Reviewed;        3664 AA.
AC   Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556;
DE   RecName: Full=Msx2-interacting protein;
DE   AltName: Full=SMART/HDAC1-associated repressor protein;
DE   AltName: Full=SPEN homolog;
GN   Name=SPEN; Synonyms=KIAA0929, MINT, SHARP;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MIOX_HUMAN              Reviewed;         285 AA.
AC   Q9UGB7; Q05DJ6; Q5S8C9; Q9BZZ1; Q9UHB8;
DE   RecName: Full=Inositol oxygenase;
DE            EC=1.13.99.1;
DE   AltName: Full=Aldehyde reductase-like 6;
DE   AltName: Full=Kidney-specific protein 32;
DE   AltName: Full=Myo-inositol oxygenase;
DE            Short=MI oxygenase;
DE   AltName: Full=Renal-specific oxidoreductase;
GN   Name=MIOX; Synonyms=ALDRL6, KSP32, RSOR;
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; ISS:UniProtKB.
DR   GO; GO:0008199; F:ferric iron binding; IDA:UniProtKB.
DR   GO; GO:0050113; F:inositol oxygenase activity; IDA:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; IEA:Ensembl.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:Ensembl.
DR   GO; GO:0016701; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; ISS:UniProtKB.
DR   GO; GO:0019310; P:inositol catabolic process; IDA:UniProtKB.
//
ID   MIO_HUMAN               Reviewed;         875 AA.
AC   Q9NXC5; B2RTV6; O75216; Q7L551; Q9H092;
DE   RecName: Full=WD repeat-containing protein mio;
GN   Name=MIOS;
//
ID   MIP18_HUMAN             Reviewed;         163 AA.
AC   Q9Y3D0;
DE   RecName: Full=Mitotic spindle-associated MMXD complex subunit MIP18;
DE   AltName: Full=MSS19-interacting protein of 18 kDa;
DE   AltName: Full=Protein FAM96B;
GN   Name=FAM96B; Synonyms=MIP18; ORFNames=CGI-128, HSPC118;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MIPEP_HUMAN             Reviewed;         713 AA.
AC   Q99797; Q5JV15; Q5T9Q9; Q96G65;
DE   RecName: Full=Mitochondrial intermediate peptidase;
DE            Short=MIP;
DE            EC=3.4.24.59;
DE   Flags: Precursor;
GN   Name=MIPEP; Synonyms=MIP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0006627; P:protein processing involved in protein targeting to mitochondrion; TAS:ProtInc.
//
ID   MIPO1_HUMAN             Reviewed;         442 AA.
AC   Q8TD10; D3DSA4; Q7Z3J0; Q8IV14;
DE   RecName: Full=Mirror-image polydactyly gene 1 protein;
GN   Name=MIPOL1;
//
ID   MIPT3_HUMAN             Reviewed;         691 AA.
AC   Q8TDR0; Q6PCT1; Q7L8N9; Q9NRD6; Q9Y4Q1;
DE   RecName: Full=TRAF3-interacting protein 1;
DE   AltName: Full=Interleukin-13 receptor alpha 1-binding protein 1;
DE   AltName: Full=Microtubule-interacting protein associated with TRAF3;
DE            Short=MIP-T3;
GN   Name=TRAF3IP1; Synonyms=MIPT3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MIP_HUMAN               Reviewed;         263 AA.
AC   P30301; Q17R41;
DE   RecName: Full=Lens fiber major intrinsic protein;
DE   AltName: Full=Aquaporin-0;
DE   AltName: Full=MIP26;
DE            Short=MP26;
GN   Name=MIP; Synonyms=AQP0;
DR   GuidetoPHARMACOLOGY; 687; -.
DR   GO; GO:0005516; F:calmodulin binding; ISS:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015250; F:water channel activity; ISS:UniProtKB.
DR   GO; GO:0015722; P:canalicular bile acid transport; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   GO; GO:0006833; P:water transport; ISS:UniProtKB.
//
ID   MIRH1_HUMAN             Reviewed;          70 AA.
AC   Q75NE6; A4QMU7; Q75NE7;
DE   RecName: Full=Putative microRNA 17 host gene protein;
DE   AltName: Full=Putative microRNA host gene 1 protein;
GN   Name=MIR17HG; Synonyms=C13orf25, MIRH1, MIRHG1;
//
ID   MIRO1_HUMAN             Reviewed;         618 AA.
AC   Q8IXI2; A4FVB6; A6NFV0; B4DG48; J9JIH9; Q6NUR3; Q6P9F8; Q6PJG1;
AC   Q6YMW8; Q86UB0; Q8IW28; Q8IXJ7; Q9H067; Q9H9N8; Q9NUZ2;
DE   RecName: Full=Mitochondrial Rho GTPase 1;
DE            Short=MIRO-1;
DE            Short=hMiro-1;
DE            EC=3.6.5.-;
DE   AltName: Full=Rac-GTP-binding protein-like protein;
DE   AltName: Full=Ras homolog gene family member T1;
GN   Name=RHOT1; Synonyms=ARHT1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; IMP:UniProtKB.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IMP:UniProtKB.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   MIRO2_HUMAN             Reviewed;         618 AA.
AC   Q8IXI1; A2IDC2; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8;
DE   RecName: Full=Mitochondrial Rho GTPase 2;
DE            Short=MIRO-2;
DE            Short=hMiro-2;
DE            EC=3.6.5.-;
DE   AltName: Full=Ras homolog gene family member T2;
GN   Name=RHOT2; Synonyms=ARHT2, C16orf39;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; IMP:UniProtKB.
DR   GO; GO:0097345; P:mitochondrial outer membrane permeabilization; IMP:UniProtKB.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   MIS12_HUMAN             Reviewed;         205 AA.
AC   Q9H081; Q96N24;
DE   RecName: Full=Protein MIS12 homolog;
GN   Name=MIS12;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0051382; P:kinetochore assembly; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   MISP_HUMAN              Reviewed;         679 AA.
AC   Q8IVT2;
DE   RecName: Full=Mitotic interactor and substrate of PLK1;
DE   AltName: Full=Mitotic spindle positioning protein;
GN   Name=MISP; Synonyms=C19orf21;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   MISSL_HUMAN             Reviewed;         245 AA.
AC   Q8NDC0; B2RDD8; Q96BG5;
DE   RecName: Full=MAPK-interacting and spindle-stabilizing protein-like;
DE   AltName: Full=Mitogen-activated protein kinase 1-interacting protein 1-like;
GN   Name=MAPK1IP1L; Synonyms=C14orf32;
//
ID   MIS_HUMAN               Reviewed;         560 AA.
AC   P03971; O75246; Q6GTN3;
DE   RecName: Full=Muellerian-inhibiting factor;
DE   AltName: Full=Anti-Muellerian hormone;
DE            Short=AMH;
DE   AltName: Full=Muellerian-inhibiting substance;
DE            Short=MIS;
DE   Flags: Precursor;
GN   Name=AMH; Synonyms=MIF;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0001880; P:Mullerian duct regression; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001546; P:preantral ovarian follicle growth; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0007530; P:sex determination; TAS:ProtInc.
DR   GO; GO:0007548; P:sex differentiation; TAS:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; IEA:Ensembl.
//
ID   MITD1_HUMAN             Reviewed;         249 AA.
AC   Q8WV92; Q69YV0;
DE   RecName: Full=MIT domain-containing protein 1;
GN   Name=MITD1;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IMP:UniProt.
DR   GO; GO:0000920; P:cytokinetic cell separation; IMP:UniProtKB.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:UniProtKB.
DR   GO; GO:1902409; P:mitotic cytokinetic cell separation; IMP:UniProt.
DR   GO; GO:0032091; P:negative regulation of protein binding; IMP:UniProt.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MITF_HUMAN              Reviewed;         526 AA.
AC   O75030; B4DJL2; D3K197; E9PFN0; Q14841; Q9P2V0; Q9P2V1; Q9P2V2;
AC   Q9P2Y8;
DE   RecName: Full=Microphthalmia-associated transcription factor;
DE   AltName: Full=Class E basic helix-loop-helix protein 32;
DE            Short=bHLHe32;
GN   Name=MITF; Synonyms=BHLHE32;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0044336; P:canonical Wnt signaling pathway involved in negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   MIXL1_HUMAN             Reviewed;         232 AA.
AC   Q9H2W2; B7ZLF9;
DE   RecName: Full=Homeobox protein MIXL1;
DE   AltName: Full=Homeodomain protein MIX;
DE            Short=hMix;
DE   AltName: Full=MIX1 homeobox-like protein 1;
DE   AltName: Full=Mix.1 homeobox-like protein;
GN   Name=MIXL1; Synonyms=MIXL;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; ISS:BHF-UCL.
DR   GO; GO:0007492; P:endoderm development; ISS:BHF-UCL.
DR   GO; GO:0035987; P:endodermal cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007369; P:gastrulation; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:1901533; P:negative regulation of hematopoietic progenitor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:2000382; P:positive regulation of mesoderm development; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   MK01_HUMAN              Reviewed;         360 AA.
AC   P28482; A8CZ64;
DE   RecName: Full=Mitogen-activated protein kinase 1;
DE            Short=MAP kinase 1;
DE            Short=MAPK 1;
DE            EC=2.7.11.24;
DE   AltName: Full=ERT1;
DE   AltName: Full=Extracellular signal-regulated kinase 2;
DE            Short=ERK-2;
DE   AltName: Full=MAP kinase isoform p42;
DE            Short=p42-MAPK;
DE   AltName: Full=Mitogen-activated protein kinase 2;
DE            Short=MAP kinase 2;
DE            Short=MAPK 2;
GN   Name=MAPK1; Synonyms=ERK2, PRKM1, PRKM2;
DR   GuidetoPHARMACOLOGY; 1495; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; TAS:ProtInc.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0019858; P:cytosine metabolic process; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038127; P:ERBB signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0000189; P:MAPK import into nucleus; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.
DR   GO; GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; ISS:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0070849; P:response to epidermal growth factor; IDA:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MK03_HUMAN              Reviewed;         379 AA.
AC   P27361; A8CZ58; B0LPG3; Q8NHX1;
DE   RecName: Full=Mitogen-activated protein kinase 3;
DE            Short=MAP kinase 3;
DE            Short=MAPK 3;
DE            EC=2.7.11.24;
DE   AltName: Full=ERT2;
DE   AltName: Full=Extracellular signal-regulated kinase 1;
DE            Short=ERK-1;
DE   AltName: Full=Insulin-stimulated MAP2 kinase;
DE   AltName: Full=MAP kinase isoform p44;
DE            Short=p44-MAPK;
DE   AltName: Full=Microtubule-associated protein 2 kinase;
DE   AltName: Full=p44-ERK1;
GN   Name=MAPK3; Synonyms=ERK1, PRKM3;
DR   GuidetoPHARMACOLOGY; 1494; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; NAS:BHF-UCL.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2000657; P:negative regulation of apolipoprotein binding; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0038083; P:peptidyl-tyrosine autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.
DR   GO; GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.
DR   GO; GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0070849; P:response to epidermal growth factor; IDA:UniProtKB.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MK06_HUMAN              Reviewed;         721 AA.
AC   Q16659; B2R945; B5BU65; Q68DH4; Q8IYN8;
DE   RecName: Full=Mitogen-activated protein kinase 6;
DE            Short=MAP kinase 6;
DE            Short=MAPK 6;
DE            EC=2.7.11.24;
DE   AltName: Full=Extracellular signal-regulated kinase 3;
DE            Short=ERK-3;
DE   AltName: Full=MAP kinase isoform p97;
DE            Short=p97-MAPK;
GN   Name=MAPK6; Synonyms=ERK3, PRKM6;
DR   GuidetoPHARMACOLOGY; 2092; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MK04_HUMAN              Reviewed;         587 AA.
AC   P31152;
DE   RecName: Full=Mitogen-activated protein kinase 4;
DE            Short=MAP kinase 4;
DE            Short=MAPK 4;
DE            EC=2.7.11.24;
DE   AltName: Full=Extracellular signal-regulated kinase 4;
DE            Short=ERK-4;
DE   AltName: Full=MAP kinase isoform p63;
DE            Short=p63-MAPK;
GN   Name=MAPK4; Synonyms=ERK4, PRKM4;
DR   GuidetoPHARMACOLOGY; 2091; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0000165; P:MAPK cascade; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   MK07_HUMAN              Reviewed;         816 AA.
AC   Q13164; Q16634; Q59F50; Q6QLU7; Q7L4P4; Q969G1; Q96G51;
DE   RecName: Full=Mitogen-activated protein kinase 7;
DE            Short=MAP kinase 7;
DE            Short=MAPK 7;
DE            EC=2.7.11.24;
DE   AltName: Full=Big MAP kinase 1;
DE            Short=BMK-1;
DE   AltName: Full=Extracellular signal-regulated kinase 5;
DE            Short=ERK-5;
GN   Name=MAPK7; Synonyms=BMK1, ERK5, PRKM7;
DR   GuidetoPHARMACOLOGY; 2093; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; TAS:ProtInc.
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IGI:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IMP:BHF-UCL.
DR   GO; GO:0071499; P:cellular response to laminar fluid shear stress; IMP:BHF-UCL.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030821; P:negative regulation of cAMP catabolic process; NAS:BHF-UCL.
DR   GO; GO:0051344; P:negative regulation of cyclic-nucleotide phosphodiesterase activity; NAS:BHF-UCL.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IGI:BHF-UCL.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IGI:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0051534; P:negative regulation of NFAT protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0060761; P:negative regulation of response to cytokine stimulus; IGI:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.
DR   GO; GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IMP:BHF-UCL.
DR   GO; GO:0045765; P:regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MK08_HUMAN              Reviewed;         427 AA.
AC   P45983; B5BTZ5; B7ZLV4; D3DX88; D3DX92; Q15709; Q15712; Q15713;
AC   Q308M2;
DE   RecName: Full=Mitogen-activated protein kinase 8;
DE            Short=MAP kinase 8;
DE            Short=MAPK 8;
DE            EC=2.7.11.24;
DE   AltName: Full=JNK-46;
DE   AltName: Full=Stress-activated protein kinase 1c;
DE            Short=SAPK1c;
DE   AltName: Full=Stress-activated protein kinase JNK1;
DE   AltName: Full=c-Jun N-terminal kinase 1;
GN   Name=MAPK8; Synonyms=JNK1, PRKM8, SAPK1, SAPK1C;
DR   GuidetoPHARMACOLOGY; 1496; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0035033; F:histone deacetylase regulator activity; IMP:BHF-UCL.
DR   GO; GO:0004705; F:JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0004707; F:MAP kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:MGI.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; IDA:UniProtKB.
DR   GO; GO:0007258; P:JUN phosphorylation; IDA:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0090045; P:positive regulation of deacetylase activity; IMP:BHF-UCL.
DR   GO; GO:2000017; P:positive regulation of determination of dorsal identity; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0031063; P:regulation of histone deacetylation; IMP:GOC.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0009411; P:response to UV; IDA:MGI.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MK09_HUMAN              Reviewed;         424 AA.
AC   P45984; A8K0S3; B5BU66; B5M0B4; D3DWQ8; D3DWQ9; Q15708; Q15710;
AC   Q15711; Q8N5C5;
DE   RecName: Full=Mitogen-activated protein kinase 9;
DE            Short=MAP kinase 9;
DE            Short=MAPK 9;
DE            EC=2.7.11.24;
DE   AltName: Full=JNK-55;
DE   AltName: Full=Stress-activated protein kinase 1a;
DE            Short=SAPK1a;
DE   AltName: Full=Stress-activated protein kinase JNK2;
DE   AltName: Full=c-Jun N-terminal kinase 2;
GN   Name=MAPK9; Synonyms=JNK2, PRKM9, SAPK1A;
DR   GuidetoPHARMACOLOGY; 1497; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0004705; F:JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; IDA:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0010770; P:positive regulation of cell morphogenesis involved in differentiation; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IEA:Ensembl.
DR   GO; GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032308; P:positive regulation of prostaglandin secretion; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IEA:Ensembl.
DR   GO; GO:0046328; P:regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MK11_HUMAN              Reviewed;         364 AA.
AC   Q15759; B0LPG1; O00284; O15472; Q2XNF2;
DE   RecName: Full=Mitogen-activated protein kinase 11;
DE            Short=MAP kinase 11;
DE            Short=MAPK 11;
DE            EC=2.7.11.24;
DE   AltName: Full=Mitogen-activated protein kinase p38 beta;
DE            Short=MAP kinase p38 beta;
DE            Short=p38b;
DE   AltName: Full=Stress-activated protein kinase 2b;
DE            Short=SAPK2b;
DE   AltName: Full=p38-2;
GN   Name=MAPK11; Synonyms=PRKM11, SAPK2, SAPK2B;
DR   GuidetoPHARMACOLOGY; 1500; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MK12_HUMAN              Reviewed;         367 AA.
AC   P53778; Q14260; Q99588; Q99672;
DE   RecName: Full=Mitogen-activated protein kinase 12;
DE            Short=MAP kinase 12;
DE            Short=MAPK 12;
DE            EC=2.7.11.24;
DE   AltName: Full=Extracellular signal-regulated kinase 6;
DE            Short=ERK-6;
DE   AltName: Full=Mitogen-activated protein kinase p38 gamma;
DE            Short=MAP kinase p38 gamma;
DE   AltName: Full=Stress-activated protein kinase 3;
GN   Name=MAPK12; Synonyms=ERK6, SAPK3;
DR   GuidetoPHARMACOLOGY; 1501; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004707; F:MAP kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0045445; P:myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MK10_HUMAN              Reviewed;         464 AA.
AC   P53779; A6NFS3; A6NG28; B3KQ94; Q15707; Q49AP1;
DE   RecName: Full=Mitogen-activated protein kinase 10;
DE            Short=MAP kinase 10;
DE            Short=MAPK 10;
DE            EC=2.7.11.24;
DE   AltName: Full=MAP kinase p49 3F12;
DE   AltName: Full=Stress-activated protein kinase 1b;
DE            Short=SAPK1b;
DE   AltName: Full=Stress-activated protein kinase JNK3;
DE   AltName: Full=c-Jun N-terminal kinase 3;
GN   Name=MAPK10; Synonyms=JNK3, JNK3A, PRKM10, SAPK1B;
DR   GuidetoPHARMACOLOGY; 1498; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004705; F:JUN kinase activity; ISS:UniProtKB.
DR   GO; GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:GOC.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; ISS:UniProtKB.
DR   GO; GO:0007258; P:JUN phosphorylation; ISS:GOC.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MK13_HUMAN              Reviewed;         365 AA.
AC   O15264; O14739; O15124; Q6FI46; Q9UNU0;
DE   RecName: Full=Mitogen-activated protein kinase 13;
DE            Short=MAP kinase 13;
DE            Short=MAPK 13;
DE            EC=2.7.11.24;
DE   AltName: Full=Mitogen-activated protein kinase p38 delta;
DE            Short=MAP kinase p38 delta;
DE   AltName: Full=Stress-activated protein kinase 4;
GN   Name=MAPK13; Synonyms=PRKM13, SAPK4;
DR   GuidetoPHARMACOLOGY; 1502; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:GOC.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006970; P:response to osmotic stress; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MK14_HUMAN              Reviewed;         360 AA.
AC   Q16539; A6ZJ92; A8K6P4; B0LPH0; O60776; Q13083; Q14084; Q8TDX0;
DE   RecName: Full=Mitogen-activated protein kinase 14;
DE            Short=MAP kinase 14;
DE            Short=MAPK 14;
DE            EC=2.7.11.24;
DE   AltName: Full=Cytokine suppressive anti-inflammatory drug-binding protein;
DE            Short=CSAID-binding protein;
DE            Short=CSBP;
DE   AltName: Full=MAP kinase MXI2;
DE   AltName: Full=MAX-interacting protein 2;
DE   AltName: Full=Mitogen-activated protein kinase p38 alpha;
DE            Short=MAP kinase p38 alpha;
DE   AltName: Full=Stress-activated protein kinase 2a;
DE            Short=SAPK2a;
GN   Name=MAPK14; Synonyms=CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A;
DR   GuidetoPHARMACOLOGY; 1499; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.
DR   GO; GO:0051525; F:NFAT protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; TAS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:MGI.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000077; P:DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0019395; P:fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:BHF-UCL.
DR   GO; GO:0038066; P:p38MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:1901741; P:positive regulation of myoblast fusion; ISS:UniProtKB.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; ISS:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0090400; P:stress-induced premature senescence; IMP:BHF-UCL.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IEA:Ensembl.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   MK15_HUMAN              Reviewed;         544 AA.
AC   Q8TD08; Q2TCF9; Q8N362;
DE   RecName: Full=Mitogen-activated protein kinase 15;
DE            Short=MAP kinase 15;
DE            Short=MAPK 15;
DE            EC=2.7.11.24;
DE   AltName: Full=Extracellular signal-regulated kinase 7;
DE            Short=ERK-7;
DE   AltName: Full=Extracellular signal-regulated kinase 8;
DE            Short=ERK-8;
GN   Name=MAPK15; Synonyms=ERK7, ERK8;
DR   GuidetoPHARMACOLOGY; 2090; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; NAS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:GOC.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
//
ID   MK67I_HUMAN             Reviewed;         293 AA.
AC   Q9BYG3; A8K788; Q8TB66; Q96ED4;
DE   RecName: Full=MKI67 FHA domain-interacting nucleolar phosphoprotein;
DE   AltName: Full=Nucleolar phosphoprotein Nopp34;
DE   AltName: Full=Nucleolar protein interacting with the FHA domain of pKI-67;
DE            Short=hNIFK;
GN   Name=NIFK; Synonyms=MKI67IP, NOPP34;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0016072; P:rRNA metabolic process; NAS:UniProtKB.
DR   GO; GO:0009303; P:rRNA transcription; NAS:UniProtKB.
//
ID   MKKS_HUMAN              Reviewed;         570 AA.
AC   Q9NPJ1; A8K7B0; D3DW18;
DE   RecName: Full=McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin;
DE   AltName: Full=Bardet-Biedl syndrome 6 protein;
GN   Name=MKKS; Synonyms=BBS6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0014824; P:artery smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060027; P:convergent extension involved in gastrulation; ISS:BHF-UCL.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; ISS:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0008406; P:gonad development; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0021766; P:hippocampus development; ISS:BHF-UCL.
DR   GO; GO:0046907; P:intracellular transport; ISS:BHF-UCL.
DR   GO; GO:0032402; P:melanosome transport; ISS:BHF-UCL.
DR   GO; GO:0038108; P:negative regulation of appetite by leptin-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; IEA:Ensembl.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:BHF-UCL.
DR   GO; GO:0051877; P:pigment granule aggregation in cell center; ISS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0060296; P:regulation of cilium beat frequency involved in ciliary motility; ISS:BHF-UCL.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; ISS:BHF-UCL.
DR   GO; GO:0007286; P:spermatid development; ISS:BHF-UCL.
DR   GO; GO:0021756; P:striatum development; ISS:BHF-UCL.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   MKL1_HUMAN              Reviewed;         931 AA.
AC   Q969V6; Q8TCL1; Q96SC5; Q96SC6; Q9P2B0;
DE   RecName: Full=MKL/myocardin-like protein 1;
DE   AltName: Full=Megakaryoblastic leukemia 1 protein;
DE   AltName: Full=Megakaryocytic acute leukemia protein;
DE   AltName: Full=Myocardin-related transcription factor A;
DE            Short=MRTF-A;
GN   Name=MKL1; Synonyms=KIAA1438, MAL;
DR   GO; GO:0003785; F:actin monomer binding; ISS:UniProtKB.
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MKLN1_HUMAN             Reviewed;         735 AA.
AC   Q9UL63; A4D1M8; A6NG43; Q9NSK4; Q9NUS8;
DE   RecName: Full=Muskelin;
GN   Name=MKLN1;
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   MKL2_HUMAN              Reviewed;        1088 AA.
AC   Q9ULH7; A6ND53; B4DGT8; Q68CT1; Q6UB16; Q86WW2; Q8N226;
DE   RecName: Full=MKL/myocardin-like protein 2;
DE   AltName: Full=Megakaryoblastic leukemia 2;
DE   AltName: Full=Myocardin-related transcription factor B;
DE            Short=MRTF-B;
GN   Name=MKL2; Synonyms=KIAA1243, MRTFB;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045844; P:positive regulation of striated muscle tissue development; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MKNK1_HUMAN             Reviewed;         465 AA.
AC   Q9BUB5; D3DQ20; D3DQ21; O00312; Q5TC06; Q5TC07; Q6V0N6;
DE   RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=MAP kinase signal-integrating kinase 1;
DE            Short=MAPK signal-integrating kinase 1;
DE            Short=Mnk1;
GN   Name=MKNK1; Synonyms=MNK1;
DR   GuidetoPHARMACOLOGY; 2104; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
//
ID   MKNK2_HUMAN             Reviewed;         465 AA.
AC   Q9HBH9; Q6GPI3; Q9HBH8; Q9UHR0; Q9Y2N6;
DE   RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=MAP kinase signal-integrating kinase 2;
DE            Short=MAPK signal-integrating kinase 2;
DE            Short=Mnk2;
GN   Name=MKNK2; Synonyms=GPRK7, MNK2;
DR   GuidetoPHARMACOLOGY; 2105; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   MKRN1_HUMAN             Reviewed;         482 AA.
AC   Q9UHC7; A4D1T7; B3KXB4; Q256Y7; Q59G11; Q6GSF1; Q9H0G0; Q9UEZ7;
AC   Q9UHW2;
DE   RecName: Full=E3 ubiquitin-protein ligase makorin-1;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 61;
GN   Name=MKRN1; Synonyms=RNF61;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MKRN2_HUMAN             Reviewed;         416 AA.
AC   Q9H000; A6NIA2; B3KRC5; Q8N391; Q96BD4; Q9BUY2; Q9NRY1;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase makorin-2;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 62;
GN   Name=MKRN2; Synonyms=RNF62; ORFNames=HSPC070;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MKRN3_HUMAN             Reviewed;         507 AA.
AC   Q13064;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase makorin-3;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 63;
DE   AltName: Full=Zinc finger protein 127;
GN   Name=MKRN3; Synonyms=D15S9, RNF63, ZNF127;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MKRN5_HUMAN             Reviewed;          33 AA.
AC   Q6NVV0;
DE   RecName: Full=Putative makorin-5;
DE   AltName: Full=Makorin ring finger protein pseudogene 6;
DE   AltName: Full=Makorin ring finger protein pseudogene 9;
DE   AltName: Full=Putative RING finger protein 65;
GN   Name=MKRN9P; Synonyms=MKRN5, MKRN9, MKRNP6, RNF65, ZNF127L3;
//
ID   MKRN4_HUMAN             Reviewed;         485 AA.
AC   Q13434;
DE   RecName: Full=Putative E3 ubiquitin-protein ligase makorin-4;
DE            EC=6.3.2.-;
DE   AltName: Full=Makorin RING finger protein pseudogene 4;
DE   AltName: Full=Makorin RING finger protein pseudogene 5;
DE   AltName: Full=RING finger protein 64;
DE   AltName: Full=Zinc finger protein 127-Xp;
DE            Short=ZNF127-Xp;
DE   AltName: Full=Zinc finger protein 127-like 1;
GN   Name=MKRN4P; Synonyms=MKRN4, MKRNP5, RNF64, ZNF127L1;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   MKS1_HUMAN              Reviewed;         559 AA.
AC   Q9NXB0; B7WNX4; F5H885; Q284T0; Q96G13;
DE   RecName: Full=Meckel syndrome type 1 protein;
GN   Name=MKS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
//
ID   MKS3_HUMAN              Reviewed;         995 AA.
AC   Q5HYA8; B3KRU5; B3KT47; G5E9H2; Q3ZCX3; Q7Z5T8; Q8IZ06;
DE   RecName: Full=Meckelin;
DE   AltName: Full=Meckel syndrome type 3 protein;
DE   AltName: Full=Transmembrane protein 67;
GN   Name=TMEM67; Synonyms=MKS3;
DR   GO; GO:0031005; F:filamin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0010826; P:negative regulation of centrosome duplication; IMP:UniProtKB.
//
ID   MK_HUMAN                Reviewed;         143 AA.
AC   P21741; Q2LEK4; Q9UCC7;
DE   RecName: Full=Midkine;
DE            Short=MK;
DE   AltName: Full=Amphiregulin-associated protein;
DE            Short=ARAP;
DE   AltName: Full=Midgestation and kidney protein;
DE   AltName: Full=Neurite outgrowth-promoting factor 2;
DE   AltName: Full=Neurite outgrowth-promoting protein;
DE   Flags: Precursor;
GN   Name=MDK; Synonyms=MK1, NEGF2;
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; ISS:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0021681; P:cerebellar granular layer development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0030421; P:defecation; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0050795; P:regulation of behavior; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; ISS:UniProtKB.
DR   GO; GO:0007614; P:short-term memory; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   ML12A_HUMAN             Reviewed;         171 AA.
AC   P19105; Q53X45;
DE   RecName: Full=Myosin regulatory light chain 12A;
DE   AltName: Full=Epididymis secretory protein Li 24;
DE            Short=HEL-S-24;
DE   AltName: Full=MLC-2B;
DE   AltName: Full=Myosin RLC;
DE   AltName: Full=Myosin regulatory light chain 2, nonsarcomeric;
DE   AltName: Full=Myosin regulatory light chain MRLC3;
GN   Name=MYL12A; Synonyms=MLCB, MRLC3, RLC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
//
ID   ML12B_HUMAN             Reviewed;         172 AA.
AC   O14950; D3DUH6; Q13182; Q7Z5Z4;
DE   RecName: Full=Myosin regulatory light chain 12B;
DE   AltName: Full=MLC-2A;
DE            Short=MLC-2;
DE   AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform;
DE   AltName: Full=Myosin regulatory light chain 20 kDa;
DE            Short=MLC20;
DE   AltName: Full=Myosin regulatory light chain MRLC2;
DE   AltName: Full=SHUJUN-1;
GN   Name=MYL12B; Synonyms=MRLC2, MYLC2B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
//
ID   MKX_HUMAN               Reviewed;         352 AA.
AC   Q8IYA7; B3KWM5;
DE   RecName: Full=Homeobox protein Mohawk;
GN   Name=MKX; Synonyms=C10orf48, IRXL1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; ISS:HGNC.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0035990; P:tendon cell differentiation; IEA:Ensembl.
DR   GO; GO:0002932; P:tendon sheath development; IEA:Ensembl.
//
ID   MLAS1_HUMAN             Reviewed;         254 AA.
AC   Q9Y6Z5; B4DW86; Q8NB23;
DE   RecName: Full=Putative uncharacterized protein MLLT4-AS1;
DE   AltName: Full=MLLT4 antisense RNA 1;
DE   AltName: Full=MLLT4 antisense gene protein 1;
DE   AltName: Full=Protein HGC6.4;
GN   Name=MLLT4-AS1; Synonyms=C6orf124;
//
ID   MLC1_HUMAN              Reviewed;         377 AA.
AC   Q15049; B3KW61; Q5JZ83; Q8TAG4; Q96RP5; Q9UGY8;
DE   RecName: Full=Membrane protein MLC1;
GN   Name=MLC1; Synonyms=KIAA0027, WKL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0072584; P:caveolin-mediated endocytosis; ISS:UniProtKB.
DR   GO; GO:0071397; P:cellular response to cholesterol; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0032388; P:positive regulation of intracellular transport; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0047484; P:regulation of response to osmotic stress; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   MLEC_HUMAN              Reviewed;         292 AA.
AC   Q14165;
DE   RecName: Full=Malectin;
DE   Flags: Precursor;
GN   Name=MLEC; Synonyms=KIAA0152;
DR   GO; GO:0030246; F:carbohydrate binding; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MLF1_HUMAN              Reviewed;         268 AA.
AC   P58340; E9PEU9; Q2TLE3; Q2TLE5; Q8N8F8; Q96MH1;
DE   RecName: Full=Myeloid leukemia factor 1;
DE   AltName: Full=Myelodysplasia-myeloid leukemia factor 1;
GN   Name=MLF1;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0002318; P:myeloid progenitor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:UniProtKB.
//
ID   MLF2_HUMAN              Reviewed;         248 AA.
AC   Q15773;
DE   RecName: Full=Myeloid leukemia factor 2;
DE   AltName: Full=Myelodysplasia-myeloid leukemia factor 2;
GN   Name=MLF2;
DR   GO; GO:0006952; P:defense response; IMP:UniProtKB.
//
ID   MLH1_HUMAN              Reviewed;         756 AA.
AC   P40692; B4DI13; B4DQ11; E9PCU2;
DE   RecName: Full=DNA mismatch repair protein Mlh1;
DE   AltName: Full=MutL protein homolog 1;
GN   Name=MLH1; Synonyms=COCA2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0032137; F:guanine/thymine mispair binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
DR   GO; GO:0007060; P:male meiosis chromosome segregation; IEA:Ensembl.
DR   GO; GO:0043060; P:meiotic metaphase I plate congression; IEA:Ensembl.
DR   GO; GO:0006298; P:mismatch repair; IGI:MGI.
DR   GO; GO:0045950; P:negative regulation of mitotic recombination; IEA:Ensembl.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IEA:Ensembl.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IEA:Ensembl.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0051257; P:spindle midzone assembly involved in meiosis; IEA:Ensembl.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   MLKL_HUMAN              Reviewed;         471 AA.
AC   Q8NB16; A6NCE4; Q8N6V0;
DE   RecName: Full=Mixed lineage kinase domain-like protein;
DE            Short=hMLKL;
GN   Name=MLKL;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0070266; P:necroptotic process; IMP:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
//
ID   MLIP_HUMAN              Reviewed;         458 AA.
AC   Q5VWP3; B7Z2N0; Q96H08; Q96NF7;
DE   RecName: Full=Muscular LMNA-interacting protein;
DE   AltName: Full=Muscular-enriched A-type laminin-interacting protein;
GN   Name=MLIP; Synonyms=C6orf142;
//
ID   MLH3_HUMAN              Reviewed;        1453 AA.
AC   Q9UHC1; P49751; Q56DK9; Q9P292; Q9UHC0;
DE   RecName: Full=DNA mismatch repair protein Mlh3;
DE   AltName: Full=MutL protein homolog 3;
GN   Name=MLH3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0019237; F:centromeric DNA binding; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003696; F:satellite DNA binding; TAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0007144; P:female meiosis I; IEA:Ensembl.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0006298; P:mismatch repair; NAS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; NAS:UniProtKB.
DR   GO; GO:0007130; P:synaptonemal complex assembly; IEA:Ensembl.
//
ID   MLP3A_HUMAN             Reviewed;         121 AA.
AC   Q9H492; E1P5P4; E1P5P5; Q9BXW5;
DE   RecName: Full=Microtubule-associated proteins 1A/1B light chain 3A;
DE   AltName: Full=Autophagy-related protein LC3 A;
DE   AltName: Full=Autophagy-related ubiquitin-like modifier LC3 A;
DE   AltName: Full=MAP1 light chain 3-like protein 1;
DE   AltName: Full=MAP1A/MAP1B light chain 3 A;
DE            Short=MAP1A/MAP1B LC3 A;
DE   AltName: Full=Microtubule-associated protein 1 light chain 3 alpha;
DE   Flags: Precursor;
GN   Name=MAP1LC3A;
DR   GO; GO:0008429; F:phosphatidylethanolamine binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:0000422; P:mitochondrion degradation; IGI:MGI.
//
ID   MLP3B_HUMAN             Reviewed;         125 AA.
AC   Q9GZQ8; Q6NW02;
DE   RecName: Full=Microtubule-associated proteins 1A/1B light chain 3B;
DE   AltName: Full=Autophagy-related protein LC3 B;
DE   AltName: Full=Autophagy-related ubiquitin-like modifier LC3 B;
DE   AltName: Full=MAP1 light chain 3-like protein 2;
DE   AltName: Full=MAP1A/MAP1B light chain 3 B;
DE            Short=MAP1A/MAP1B LC3 B;
DE   AltName: Full=Microtubule-associated protein 1 light chain 3 beta;
DE   Flags: Precursor;
GN   Name=MAP1LC3B; Synonyms=MAP1ALC3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   MLP3C_HUMAN             Reviewed;         147 AA.
AC   Q9BXW4; A0PJY8; A2RUP0;
DE   RecName: Full=Microtubule-associated proteins 1A/1B light chain 3C;
DE   AltName: Full=Autophagy-related protein LC3 C;
DE   AltName: Full=Autophagy-related ubiquitin-like modifier LC3 C;
DE   AltName: Full=MAP1 light chain 3-like protein 3;
DE   AltName: Full=MAP1A/MAP1B light chain 3 C;
DE            Short=MAP1A/MAP1B LC3 C;
DE   AltName: Full=Microtubule-associated protein 1 light chain 3 gamma;
DE   Flags: Precursor;
GN   Name=MAP1LC3C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   MLRA_HUMAN              Reviewed;         175 AA.
AC   Q01449; B2R4L3;
DE   RecName: Full=Myosin regulatory light chain 2, atrial isoform;
DE            Short=MLC-2a;
DE            Short=MLC2a;
DE            Short=Myosin light chain 2a;
DE   AltName: Full=Myosin regulatory light chain 7;
GN   Name=MYL7; Synonyms=MYL2A, MYLC2A;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   MLRS_HUMAN              Reviewed;         169 AA.
AC   Q96A32; B2RA83; Q14843; Q6IB41;
DE   RecName: Full=Myosin regulatory light chain 2, skeletal muscle isoform;
DE   AltName: Full=Fast skeletal myosin light chain 2;
DE   AltName: Full=MLC2B;
GN   Name=MYLPF;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008307; F:structural constituent of muscle; ISS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; ISS:BHF-UCL.
//
ID   MLRV_HUMAN              Reviewed;         166 AA.
AC   P10916; Q16123;
DE   RecName: Full=Myosin regulatory light chain 2, ventricular/cardiac muscle isoform;
DE            Short=MLC-2;
DE            Short=MLC-2v;
GN   Name=MYL2;
DR   GO; GO:0003785; F:actin monomer binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IDA:MGI.
DR   GO; GO:0032036; F:myosin heavy chain binding; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.
DR   GO; GO:0060047; P:heart contraction; ISS:BHF-UCL.
DR   GO; GO:0042694; P:muscle cell fate specification; IEA:Ensembl.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; TAS:ProtInc.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   MLTK_HUMAN              Reviewed;         800 AA.
AC   Q9NYL2; B3KPG2; Q53SX1; Q580W8; Q59GY5; Q86YW8; Q9HCC4; Q9HCC5;
AC   Q9HDD2; Q9NYE9;
DE   RecName: Full=Mitogen-activated protein kinase kinase kinase MLT;
DE            EC=2.7.11.25;
DE   AltName: Full=Human cervical cancer suppressor gene 4 protein;
DE            Short=HCCS-4;
DE   AltName: Full=Leucine zipper- and sterile alpha motif-containing kinase;
DE   AltName: Full=MLK-like mitogen-activated protein triple kinase;
DE   AltName: Full=Mixed lineage kinase-related kinase;
DE            Short=MLK-related kinase;
DE            Short=MRK;
DE   AltName: Full=Sterile alpha motif- and leucine zipper-containing kinase AZK;
GN   Name=ZAK; Synonyms=MLTK; ORFNames=HCCS4;
DR   GuidetoPHARMACOLOGY; 2289; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   MLXIP_HUMAN             Reviewed;         919 AA.
AC   Q9HAP2; A7MBN0; O94945; Q7LC47; Q8IXP1; Q8TAH9; Q8WVQ0; Q8WYA5;
DE   RecName: Full=MLX-interacting protein;
DE   AltName: Full=Class E basic helix-loop-helix protein 36;
DE            Short=bHLHe36;
DE   AltName: Full=Transcriptional activator MondoA;
GN   Name=MLXIP; Synonyms=BHLHE36, KIAA0867, MIR, MONDOA;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MLXPL_HUMAN             Reviewed;         852 AA.
AC   Q9NP71; C5HU02; C5HU03; C5HU04; Q96E48; Q9BY03; Q9BY04; Q9BY05;
AC   Q9BY06; Q9Y2P3;
DE   RecName: Full=Carbohydrate-responsive element-binding protein;
DE            Short=ChREBP;
DE   AltName: Full=Class D basic helix-loop-helix protein 14;
DE            Short=bHLHd14;
DE   AltName: Full=MLX interactor;
DE   AltName: Full=MLX-interacting protein-like;
DE   AltName: Full=WS basic-helix-loop-helix leucine zipper protein;
DE            Short=WS-bHLH;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 14 protein;
GN   Name=MLXIPL; Synonyms=BHLHD14, MIO, WBSCR14;
DR   GO; GO:0035538; F:carbohydrate response element binding; TAS:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; NAS:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:BHF-UCL.
DR   GO; GO:0010255; P:glucose mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:Reactome.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0090324; P:negative regulation of oxidative phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0045821; P:positive regulation of glycolytic process; IMP:BHF-UCL.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0070328; P:triglyceride homeostasis; NAS:BHF-UCL.
//
ID   MLX_HUMAN               Reviewed;         298 AA.
AC   Q9UH92; A8K2J3; B2RAV8; B2RD73; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1;
AC   Q9H2V2; Q9NXN3;
DE   RecName: Full=Max-like protein X;
DE   AltName: Full=Class D basic helix-loop-helix protein 13;
DE            Short=bHLHd13;
DE   AltName: Full=Max-like bHLHZip protein;
DE   AltName: Full=Protein BigMax;
DE   AltName: Full=Transcription factor-like protein 4;
GN   Name=MLX; Synonyms=BHLHD13, TCFL4;
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MMAA_HUMAN              Reviewed;         418 AA.
AC   Q8IVH4; B3KX40; Q495G7;
DE   RecName: Full=Methylmalonic aciduria type A protein, mitochondrial;
DE            EC=3.6.-.-;
DE   Flags: Precursor;
GN   Name=MMAA;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MMAB_HUMAN              Reviewed;         250 AA.
AC   Q96EY8; C5HU05; Q9BSH0;
DE   RecName: Full=Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial;
DE            EC=2.5.1.17;
DE   AltName: Full=Cob(I)alamin adenosyltransferase;
DE   AltName: Full=Methylmalonic aciduria type B protein;
DE   Flags: Precursor;
GN   Name=MMAB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008817; F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity; TAS:Reactome.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MMAC_HUMAN              Reviewed;         282 AA.
AC   Q9Y4U1; Q5T157; Q9BRQ7;
DE   RecName: Full=Methylmalonic aciduria and homocystinuria type C protein;
GN   Name=MMACHC;
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MMAD_HUMAN              Reviewed;         296 AA.
AC   Q9H3L0; B2R895; D3DP91; O95891;
DE   RecName: Full=Methylmalonic aciduria and homocystinuria type D protein, mitochondrial;
DE   Flags: Precursor;
GN   Name=MMADHC; Synonyms=C2orf25, CL25022; ORFNames=HSPC161, My011;
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MMEL1_HUMAN             Reviewed;         779 AA.
AC   Q495T6; B9DI79; Q495T7; Q495T8; Q5SZS6; Q96PH9;
DE   RecName: Full=Membrane metallo-endopeptidase-like 1;
DE            EC=3.4.24.11;
DE   AltName: Full=Membrane metallo-endopeptidase-like 2;
DE   AltName: Full=NEP2(m);
DE   AltName: Full=Neprilysin II;
DE            Short=NEPII;
DE   AltName: Full=Neprilysin-2;
DE            Short=NEP2;
DE            Short=NL2;
DE   Contains:
DE     RecName: Full=Membrane metallo-endopeptidase-like 1, soluble form;
DE     AltName: Full=Neprilysin-2 secreted;
DE              Short=NEP2(s);
GN   Name=MMEL1; Synonyms=MELL1, MMEL2, NEP2;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
//
ID   MMGT1_HUMAN             Reviewed;         131 AA.
AC   Q8N4V1; B2R625; B4DIY3; D3DWG7; Q5JPP7;
DE   RecName: Full=Membrane magnesium transporter 1;
DE   AltName: Full=ER membrane protein complex subunit 5;
DE   AltName: Full=Transmembrane protein 32;
DE   Flags: Precursor;
GN   Name=MMGT1; Synonyms=EMC5, TMEM32;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015693; P:magnesium ion transport; ISS:UniProtKB.
//
ID   MMP10_HUMAN             Reviewed;         476 AA.
AC   P09238; B2R9X9; Q53HH9;
DE   RecName: Full=Stromelysin-2;
DE            Short=SL-2;
DE            EC=3.4.24.22;
DE   AltName: Full=Matrix metalloproteinase-10;
DE            Short=MMP-10;
DE   AltName: Full=Transin-2;
DE   Flags: Precursor;
GN   Name=MMP10; Synonyms=STMY2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
//
ID   MMP11_HUMAN             Reviewed;         488 AA.
AC   P24347; Q5FX24; Q6PEZ6; Q9UC26;
DE   RecName: Full=Stromelysin-3;
DE            Short=SL-3;
DE            Short=ST3;
DE            EC=3.4.24.-;
DE   AltName: Full=Matrix metalloproteinase-11;
DE            Short=MMP-11;
DE   Flags: Precursor;
GN   Name=MMP11; Synonyms=STMY3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071711; P:basement membrane organization; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   MMP12_HUMAN             Reviewed;         470 AA.
AC   P39900; B2R9X8; B7ZLF6; Q2M1L9;
DE   RecName: Full=Macrophage metalloelastase;
DE            Short=MME;
DE            EC=3.4.24.65;
DE   AltName: Full=Macrophage elastase;
DE            Short=ME;
DE            Short=hME;
DE   AltName: Full=Matrix metalloproteinase-12;
DE            Short=MMP-12;
DE   Flags: Precursor;
GN   Name=MMP12; Synonyms=HME;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004175; F:endopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060054; P:positive regulation of epithelial cell proliferation involved in wound healing; IDA:BHF-UCL.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IDA:BHF-UCL.
//
ID   MMP13_HUMAN             Reviewed;         471 AA.
AC   P45452; A8K846; B2RCZ3; Q6NWN6;
DE   RecName: Full=Collagenase 3;
DE            EC=3.4.24.-;
DE   AltName: Full=Matrix metalloproteinase-13;
DE            Short=MMP-13;
DE   Flags: Precursor;
GN   Name=MMP13;
DR   GuidetoPHARMACOLOGY; 1637; -.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0060349; P:bone morphogenesis; IDA:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:UniProtKB.
DR   GO; GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   MMP14_HUMAN             Reviewed;         582 AA.
AC   P50281; A8K5L0; Q6GSF3; Q92678;
DE   RecName: Full=Matrix metalloproteinase-14;
DE            Short=MMP-14;
DE            EC=3.4.24.80;
DE   AltName: Full=MMP-X1;
DE   AltName: Full=Membrane-type matrix metalloproteinase 1;
DE            Short=MT-MMP 1;
DE            Short=MTMMP1;
DE   AltName: Full=Membrane-type-1 matrix metalloproteinase;
DE            Short=MT1-MMP;
DE            Short=MT1MMP;
DE   Flags: Precursor;
GN   Name=MMP14;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0016504; F:peptidase activator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0043615; P:astrocyte cell migration; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0001935; P:endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0048771; P:tissue remodeling; IEA:Ensembl.
DR   GO; GO:0031638; P:zymogen activation; IEA:Ensembl.
//
ID   MMP16_HUMAN             Reviewed;         607 AA.
AC   P51512; B2RAN7; Q14824; Q52H48;
DE   RecName: Full=Matrix metalloproteinase-16;
DE            Short=MMP-16;
DE            EC=3.4.24.-;
DE   AltName: Full=MMP-X2;
DE   AltName: Full=Membrane-type matrix metalloproteinase 3;
DE            Short=MT-MMP 3;
DE            Short=MTMMP3;
DE   AltName: Full=Membrane-type-3 matrix metalloproteinase;
DE            Short=MT3-MMP;
DE            Short=MT3MMP;
DE   Flags: Precursor;
GN   Name=MMP16; Synonyms=MMPX2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
//
ID   MMP15_HUMAN             Reviewed;         669 AA.
AC   P51511; A0A2U6; Q14111;
DE   RecName: Full=Matrix metalloproteinase-15;
DE            Short=MMP-15;
DE            EC=3.4.24.-;
DE   AltName: Full=Membrane-type matrix metalloproteinase 2;
DE            Short=MT-MMP 2;
DE            Short=MTMMP2;
DE   AltName: Full=Membrane-type-2 matrix metalloproteinase;
DE            Short=MT2-MMP;
DE            Short=MT2MMP;
DE   AltName: Full=SMCP-2;
DE   Flags: Precursor;
GN   Name=MMP15;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
//
ID   MMP17_HUMAN             Reviewed;         603 AA.
AC   Q9ULZ9; Q14850;
DE   RecName: Full=Matrix metalloproteinase-17;
DE            Short=MMP-17;
DE            EC=3.4.24.-;
DE   AltName: Full=Membrane-type matrix metalloproteinase 4;
DE            Short=MT-MMP 4;
DE            Short=MTMMP4;
DE   AltName: Full=Membrane-type-4 matrix metalloproteinase;
DE            Short=MT4-MMP;
DE            Short=MT4MMP;
DE   Flags: Precursor;
GN   Name=MMP17; Synonyms=MT4MMP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
//
ID   MMP19_HUMAN             Reviewed;         508 AA.
AC   Q99542; B4E030; O15278; O95606; Q99580;
DE   RecName: Full=Matrix metalloproteinase-19;
DE            Short=MMP-19;
DE            EC=3.4.24.-;
DE   AltName: Full=Matrix metalloproteinase RASI;
DE   AltName: Full=Matrix metalloproteinase-18;
DE            Short=MMP-18;
DE   Flags: Precursor;
GN   Name=MMP19; Synonyms=MMP18, RASI;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001554; P:luteolysis; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
//
ID   MMP1_HUMAN              Reviewed;         469 AA.
AC   P03956; P08156;
DE   RecName: Full=Interstitial collagenase;
DE            EC=3.4.24.7;
DE   AltName: Full=Fibroblast collagenase;
DE   AltName: Full=Matrix metalloproteinase-1;
DE            Short=MMP-1;
DE   Contains:
DE     RecName: Full=22 kDa interstitial collagenase;
DE   Contains:
DE     RecName: Full=27 kDa interstitial collagenase;
DE   Flags: Precursor;
GN   Name=MMP1; Synonyms=CLG;
DR   GuidetoPHARMACOLOGY; 1628; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MMP20_HUMAN             Reviewed;         483 AA.
AC   O60882; Q6DKT9;
DE   RecName: Full=Matrix metalloproteinase-20;
DE            Short=MMP-20;
DE            EC=3.4.24.-;
DE   AltName: Full=Enamel metalloproteinase;
DE   AltName: Full=Enamelysin;
DE   Flags: Precursor;
GN   Name=MMP20;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0097186; P:amelogenesis; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0070173; P:regulation of enamel mineralization; TAS:BHF-UCL.
//
ID   MMP21_HUMAN             Reviewed;         569 AA.
AC   Q8N119; Q5VZP9; Q8NG02;
DE   RecName: Full=Matrix metalloproteinase-21;
DE            Short=MMP-21;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=MMP21;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MMP23_HUMAN             Reviewed;         390 AA.
AC   O75900; A2AGN0; A2AGN1; O75894; O75895; Q5QPQ8; Q76P96; Q7LDM6;
AC   Q7LDM7; Q9UBR9; Q9UJK8;
DE   RecName: Full=Matrix metalloproteinase-23;
DE            Short=MMP-23;
DE            EC=3.4.24.-;
DE   AltName: Full=Femalysin;
DE   AltName: Full=MIFR-1;
DE   AltName: Full=Matrix metalloproteinase-21;
DE            Short=MMP-21;
DE   AltName: Full=Matrix metalloproteinase-22;
DE            Short=MMP-22;
DE   Contains:
DE     RecName: Full=Matrix metalloproteinase-23, soluble form;
DE   Flags: Precursor;
GN   Name=MMP23A; Synonyms=MMP21;
GN   and
GN   Name=MMP23B; Synonyms=MMP21, MMP22;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008237; F:metallopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0000003; P:reproduction; IEP:UniProtKB.
//
ID   MMP24_HUMAN             Reviewed;         645 AA.
AC   Q9Y5R2; B7ZBG8; Q9H440;
DE   RecName: Full=Matrix metalloproteinase-24;
DE            Short=MMP-24;
DE            EC=3.4.24.-;
DE   AltName: Full=Membrane-type matrix metalloproteinase 5;
DE            Short=MT-MMP 5;
DE            Short=MTMMP5;
DE   AltName: Full=Membrane-type-5 matrix metalloproteinase;
DE            Short=MT5-MMP;
DE            Short=MT5MMP;
DE   Contains:
DE     RecName: Full=Processed matrix metalloproteinase-24;
DE   Flags: Precursor;
GN   Name=MMP24; Synonyms=MT5MMP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   MMP25_HUMAN             Reviewed;         562 AA.
AC   Q9NPA2; D3DUA8; Q9H3Q0;
DE   RecName: Full=Matrix metalloproteinase-25;
DE            Short=MMP-25;
DE            EC=3.4.24.-;
DE   AltName: Full=Leukolysin;
DE   AltName: Full=Membrane-type matrix metalloproteinase 6;
DE            Short=MT-MMP 6;
DE            Short=MTMMP6;
DE   AltName: Full=Membrane-type-6 matrix metalloproteinase;
DE            Short=MT6-MMP;
DE            Short=MT6MMP;
DE   Flags: Precursor;
GN   Name=MMP25; Synonyms=MMP20, MMPL1, MT6MMP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060022; P:hard palate development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   MMP26_HUMAN             Reviewed;         261 AA.
AC   Q9NRE1; Q3MJ78; Q9GZS2; Q9NR87;
DE   RecName: Full=Matrix metalloproteinase-26;
DE            Short=MMP-26;
DE            EC=3.4.24.-;
DE   AltName: Full=Endometase;
DE   AltName: Full=Matrilysin-2;
DE   Flags: Precursor;
GN   Name=MMP26;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   MMP27_HUMAN             Reviewed;         513 AA.
AC   Q9H306; Q6UWK6;
DE   RecName: Full=Matrix metalloproteinase-27;
DE            Short=MMP-27;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=MMP27; ORFNames=UNQ2503/PRO5992;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
//
ID   MMP2_HUMAN              Reviewed;         660 AA.
AC   P08253; B2R6U1; B4DWH3; E9PE45; Q9UCJ8;
DE   RecName: Full=72 kDa type IV collagenase;
DE            EC=3.4.24.24;
DE   AltName: Full=72 kDa gelatinase;
DE   AltName: Full=Gelatinase A;
DE   AltName: Full=Matrix metalloproteinase-2;
DE            Short=MMP-2;
DE   AltName: Full=TBE-1;
DE   Contains:
DE     RecName: Full=PEX;
DE   Flags: Precursor;
GN   Name=MMP2; Synonyms=CLG4A;
DR   GuidetoPHARMACOLOGY; 1629; -.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001955; P:blood vessel maturation; IEA:Ensembl.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0001957; P:intramembranous ossification; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   MMP28_HUMAN             Reviewed;         520 AA.
AC   Q9H239; Q96F04; Q96TE2;
DE   RecName: Full=Matrix metalloproteinase-28;
DE            Short=MMP-28;
DE            EC=3.4.24.-;
DE   AltName: Full=Epilysin;
DE   Flags: Precursor;
GN   Name=MMP28; Synonyms=MMP25; ORFNames=UNQ1893/PRO4339;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MMP3_HUMAN              Reviewed;         477 AA.
AC   P08254; B2R8B8; Q3B7S0; Q6GRF8;
DE   RecName: Full=Stromelysin-1;
DE            Short=SL-1;
DE            EC=3.4.24.17;
DE   AltName: Full=Matrix metalloproteinase-3;
DE            Short=MMP-3;
DE   AltName: Full=Transin-1;
DE   Flags: Precursor;
GN   Name=MMP3; Synonyms=STMY1;
DR   GuidetoPHARMACOLOGY; 1630; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
//
ID   MMP7_HUMAN              Reviewed;         267 AA.
AC   P09237; Q9BTK9;
DE   RecName: Full=Matrilysin;
DE            EC=3.4.24.23;
DE   AltName: Full=Matrin;
DE   AltName: Full=Matrix metalloproteinase-7;
DE            Short=MMP-7;
DE   AltName: Full=Pump-1 protease;
DE   AltName: Full=Uterine metalloproteinase;
DE   Flags: Precursor;
GN   Name=MMP7; Synonyms=MPSL1, PUMP1;
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002779; P:antibacterial peptide secretion; IEA:Ensembl.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   MMP8_HUMAN              Reviewed;         467 AA.
AC   P22894; Q45F99;
DE   RecName: Full=Neutrophil collagenase;
DE            EC=3.4.24.34;
DE   AltName: Full=Matrix metalloproteinase-8;
DE            Short=MMP-8;
DE   AltName: Full=PMNL collagenase;
DE            Short=PMNL-CL;
DE   Flags: Precursor;
GN   Name=MMP8; Synonyms=CLG1;
DR   GuidetoPHARMACOLOGY; 1632; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   MMP9_HUMAN              Reviewed;         707 AA.
AC   P14780; B2R7V9; Q3LR70; Q8N725; Q9H4Z1; Q9UCJ9; Q9UCL1; Q9UDK2;
DE   RecName: Full=Matrix metalloproteinase-9;
DE            Short=MMP-9;
DE            EC=3.4.24.35;
DE   AltName: Full=92 kDa gelatinase;
DE   AltName: Full=92 kDa type IV collagenase;
DE   AltName: Full=Gelatinase B;
DE            Short=GELB;
DE   Contains:
DE     RecName: Full=67 kDa matrix metalloproteinase-9;
DE   Contains:
DE     RecName: Full=82 kDa matrix metalloproteinase-9;
DE   Flags: Precursor;
GN   Name=MMP9; Synonyms=CLG4B;
DR   GuidetoPHARMACOLOGY; 1633; -.
DR   GO; GO:0005518; F:collagen binding; TAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; TAS:Reactome.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; IEA:InterPro.
DR   GO; GO:0030225; P:macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:2001258; P:negative regulation of cation channel activity; IDA:UniProt.
DR   GO; GO:0001503; P:ossification; IEA:InterPro.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051549; P:positive regulation of keratinocyte migration; IMP:BHF-UCL.
DR   GO; GO:1900122; P:positive regulation of receptor binding; IDA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   MMRN1_HUMAN             Reviewed;        1228 AA.
AC   Q13201; Q4W5L1; Q6P3T8; Q6ZUL9;
DE   RecName: Full=Multimerin-1;
DE   AltName: Full=EMILIN-4;
DE   AltName: Full=Elastin microfibril interface located protein 4;
DE            Short=Elastin microfibril interfacer 4;
DE   AltName: Full=Endothelial cell multimerin;
DE   Contains:
DE     RecName: Full=Platelet glycoprotein Ia*;
DE   Contains:
DE     RecName: Full=155 kDa platelet multimerin;
DE              Short=p-155;
DE              Short=p155;
DE   Flags: Precursor;
GN   Name=MMRN1; Synonyms=ECM, EMILIN4, GPIA*, MMRN;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   MMRN2_HUMAN             Reviewed;         949 AA.
AC   Q9H8L6; Q504V7; Q6P2N2;
DE   RecName: Full=Multimerin-2;
DE   AltName: Full=EMILIN-3;
DE   AltName: Full=Elastin microfibril interface located protein 3;
DE            Short=Elastin microfibril interfacer 3;
DE   AltName: Full=EndoGlyx-1 p125/p140 subunit;
DE   Flags: Precursor;
GN   Name=MMRN2; Synonyms=EMILIN3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
//
ID   MMS19_HUMAN             Reviewed;        1030 AA.
AC   Q96T76; B0QZ75; B3KPE5; B4DQX2; B4E2I3; D3DR55; F8W9Y2; Q17RZ8;
AC   Q5T455; Q66K82; Q7L4W8; Q969Z1; Q96DF1; Q96MR1; Q96RK5; Q96SK1;
AC   Q9BUE2; Q9BYS9;
DE   RecName: Full=MMS19 nucleotide excision repair protein homolog;
DE            Short=hMMS19;
DE   AltName: Full=MET18 homolog;
DE   AltName: Full=MMS19-like protein;
GN   Name=MMS19; Synonyms=MMS19L;
DR   GO; GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006259; P:DNA metabolic process; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; NAS:UniProtKB.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   MMS22_HUMAN             Reviewed;        1243 AA.
AC   Q6ZRQ5; D6R9Y8; D6RBQ4; E1P529; Q5THT2; Q68CQ6; Q68D32;
DE   RecName: Full=Protein MMS22-like;
DE   AltName: Full=Methyl methanesulfonate-sensitivity protein 22-like;
GN   Name=MMS22L; Synonyms=C6orf167;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
//
ID   MMSA_HUMAN              Reviewed;         535 AA.
AC   Q02252; B2R609; Q9UKM8;
DE   RecName: Full=Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial;
DE            Short=MMSDH;
DE            Short=Malonate-semialdehyde dehydrogenase [acylating];
DE            EC=1.2.1.18;
DE            EC=1.2.1.27;
DE   AltName: Full=Aldehyde dehydrogenase family 6 member A1;
DE   Flags: Precursor;
GN   Name=ALDH6A1; Synonyms=MMSDH;
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; ISS:UniProtKB.
DR   GO; GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; ISS:UniProtKB.
DR   GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating) activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006210; P:thymine catabolic process; IMP:BHF-UCL.
DR   GO; GO:0019859; P:thymine metabolic process; ISS:UniProtKB.
DR   GO; GO:0006574; P:valine catabolic process; IMP:BHF-UCL.
DR   GO; GO:0006573; P:valine metabolic process; ISS:UniProtKB.
//
ID   MMTA2_HUMAN             Reviewed;         263 AA.
AC   Q9BU76; Q6P5Y0; Q6ZTZ6; Q6ZWA6; Q8IZH3;
DE   RecName: Full=Multiple myeloma tumor-associated protein 2;
DE            Short=hMMTAG2;
GN   Name=MMTAG2; Synonyms=C1orf35;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MN1_HUMAN               Reviewed;        1320 AA.
AC   Q10571; A9Z1V9;
DE   RecName: Full=Probable tumor suppressor protein MN1;
GN   Name=MN1;
DR   GO; GO:0001957; P:intramembranous ossification; IEA:Ensembl.
//
ID   MND1_HUMAN              Reviewed;         205 AA.
AC   Q9BWT6; B2R5F9;
DE   RecName: Full=Meiotic nuclear division protein 1 homolog;
GN   Name=MND1; Synonyms=GAJ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   MNDA_HUMAN              Reviewed;         407 AA.
AC   P41218;
DE   RecName: Full=Myeloid cell nuclear differentiation antigen;
GN   Name=MNDA;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MNS1_HUMAN              Reviewed;         495 AA.
AC   Q8NEH6; Q8IYT6; Q9NUP4;
DE   RecName: Full=Meiosis-specific nuclear structural protein 1;
GN   Name=MNS1;
DR   GO; GO:0042802; F:identical protein binding; IDA:MGI.
DR   GO; GO:0044782; P:cilium organization; IEA:Ensembl.
DR   GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   MNT_HUMAN               Reviewed;         582 AA.
AC   Q99583; A8K6D1; D3DTI7; Q1ED38;
DE   RecName: Full=Max-binding protein MNT;
DE   AltName: Full=Class D basic helix-loop-helix protein 3;
DE            Short=bHLHd3;
DE   AltName: Full=Myc antagonist MNT;
DE   AltName: Full=Protein ROX;
GN   Name=MNT; Synonyms=BHLHD3, ROX;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MNX1_HUMAN              Reviewed;         401 AA.
AC   P50219; F5H401; Q9Y648;
DE   RecName: Full=Motor neuron and pancreas homeobox protein 1;
DE   AltName: Full=Homeobox protein HB9;
GN   Name=MNX1; Synonyms=HLXB9;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0060539; P:diaphragm development; IEA:Ensembl.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MO2R1_HUMAN             Reviewed;         325 AA.
AC   Q8TD46; B3KWZ9; E9PCM9; Q52LJ7; Q6IS95; Q6UW94; Q6WHB8; Q8TD44;
AC   Q8TD45; Q8TD52;
DE   RecName: Full=Cell surface glycoprotein CD200 receptor 1;
DE   AltName: Full=CD200 cell surface glycoprotein receptor;
DE   AltName: Full=Cell surface glycoprotein OX2 receptor 1;
DE   Flags: Precursor;
GN   Name=CD200R1; Synonyms=CD200R, CRTR2, MOX2R, OX2R;
GN   ORFNames=UNQ2522/PRO6015;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MO2R2_HUMAN             Reviewed;         271 AA.
AC   Q6Q8B3; Q6WHB7;
DE   RecName: Full=Cell surface glycoprotein CD200 receptor 2;
DE   AltName: Full=CD200 cell surface glycoprotein receptor-like 2;
DE            Short=CD200 receptor-like 2;
DE            Short=HuCD200R2;
DE   AltName: Full=CD200 cell surface glycoprotein receptor-like a;
DE            Short=CD200RLa;
DE   AltName: Full=Cell surface glycoprotein CD200 receptor 1-like;
DE   AltName: Full=Cell surface glycoprotein OX2 receptor 2;
DE   Flags: Precursor;
GN   Name=CD200R1L; Synonyms=CD200R2;
//
ID   MO4L1_HUMAN             Reviewed;         362 AA.
AC   Q9UBU8; B4DKN6; B7Z6R1; D3DW88; O95899; Q5QTS1; Q6NVX8; Q86YT7;
AC   Q9HBP6; Q9NSW5;
DE   RecName: Full=Mortality factor 4-like protein 1;
DE   AltName: Full=MORF-related gene 15 protein;
DE   AltName: Full=Protein MSL3-1;
DE   AltName: Full=Transcription factor-like protein MRG15;
GN   Name=MORF4L1; Synonyms=MRG15;
GN   ORFNames=FWP006, HSPC008, HSPC061, PP368;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MO4L2_HUMAN             Reviewed;         288 AA.
AC   Q15014; B3KP92; D3DXA5; Q567V0; Q8J026;
DE   RecName: Full=Mortality factor 4-like protein 2;
DE   AltName: Full=MORF-related gene X protein;
DE   AltName: Full=Protein MSL3-2;
DE   AltName: Full=Transcription factor-like protein MRGX;
GN   Name=MORF4L2; Synonyms=KIAA0026, MRGX;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0051155; P:positive regulation of striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MOAP1_HUMAN             Reviewed;         351 AA.
AC   Q96BY2; B2RDF6; Q9H833; Q9HAS1;
DE   RecName: Full=Modulator of apoptosis 1;
DE            Short=MAP-1;
DE            Short=MAP1;
DE   AltName: Full=Paraneoplastic antigen Ma4;
GN   Name=MOAP1; Synonyms=PNMA4;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:BHF-UCL.
DR   GO; GO:0001844; P:protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; IMP:BHF-UCL.
//
ID   MOB1A_HUMAN             Reviewed;         216 AA.
AC   Q9H8S9; Q53S34; Q9H3T5; Q9HAI0; Q9NVE2;
DE   RecName: Full=MOB kinase activator 1A;
DE   AltName: Full=Mob1 alpha;
DE            Short=Mob1A;
DE   AltName: Full=Mob1 homolog 1B;
DE   AltName: Full=Mps one binder kinase activator-like 1B;
GN   Name=MOB1A; Synonyms=C2orf6, MOB4B, MOBK1B, MOBKL1B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
//
ID   MOB1B_HUMAN             Reviewed;         216 AA.
AC   Q7L9L4; B2R8U6; B4DRY3; Q8IY23;
DE   RecName: Full=MOB kinase activator 1B;
DE   AltName: Full=Mob1 homolog 1A;
DE            Short=Mob1A;
DE   AltName: Full=Mob1B;
DE   AltName: Full=Mps one binder kinase activator-like 1A;
GN   Name=MOB1B; Synonyms=MOB4A, MOBKL1A;
DR   GO; GO:0019209; F:kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
//
ID   MOB2_HUMAN              Reviewed;         237 AA.
AC   Q70IA6; B4DKP3; Q96M67;
DE   RecName: Full=MOB kinase activator 2;
DE   AltName: Full=HCCA2;
DE   AltName: Full=Mob2 homolog;
DE   AltName: Full=Mps one binder kinase activator-like 2;
GN   Name=MOB2; Synonyms=HCCA2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
//
ID   MOB3A_HUMAN             Reviewed;         217 AA.
AC   Q96BX8; B3KTF1; O75249; Q8TF69;
DE   RecName: Full=MOB kinase activator 3A;
DE   AltName: Full=MOB-LAK;
DE   AltName: Full=Mob1 homolog 2A;
DE   AltName: Full=Mps one binder kinase activator-like 2A;
GN   Name=MOB3A; Synonyms=MOBKL2A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   MOB3B_HUMAN             Reviewed;         216 AA.
AC   Q86TA1; Q8NEB4; Q9H8V4;
DE   RecName: Full=MOB kinase activator 3B;
DE   AltName: Full=Mob1 homolog 2b;
DE   AltName: Full=Mps one binder kinase activator-like 2B;
GN   Name=MOB3B; Synonyms=MOBKL2B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MOB3C_HUMAN             Reviewed;         216 AA.
AC   Q70IA8; D3DQ22; Q0VA98; Q5TC10; Q5TC11; Q8NAZ2; Q8NF28;
DE   RecName: Full=MOB kinase activator 3C;
DE   AltName: Full=Mob1 homolog 2C;
DE   AltName: Full=Mps one binder kinase activator-like 2C;
GN   Name=MOB3C; Synonyms=MOBKL2C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   MOBP_HUMAN              Reviewed;         183 AA.
AC   Q13875; A8K2C2; Q13874; Q6DHZ6; Q8TBJ1;
DE   RecName: Full=Myelin-associated oligodendrocyte basic protein;
GN   Name=MOBP;
DR   GO; GO:0019911; F:structural constituent of myelin sheath; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   MOC2A_HUMAN             Reviewed;          88 AA.
AC   O96033;
DE   RecName: Full=Molybdopterin synthase sulfur carrier subunit;
DE   AltName: Full=MOCO1-A;
DE   AltName: Full=Molybdenum cofactor synthesis protein 2 small subunit;
DE   AltName: Full=Molybdenum cofactor synthesis protein 2A;
DE            Short=MOCS2A;
DE   AltName: Full=Molybdopterin-synthase small subunit;
DE   AltName: Full=Sulfur carrier protein MOCS2A;
GN   Name=MOCS2; Synonyms=MOCO1;
DR   GO; GO:0030366; F:molybdopterin synthase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MOC2B_HUMAN             Reviewed;         188 AA.
AC   O96007; Q6IAI3;
DE   RecName: Full=Molybdopterin synthase catalytic subunit;
DE            EC=2.8.1.12;
DE   AltName: Full=MOCO1-B;
DE   AltName: Full=Molybdenum cofactor synthesis protein 2 large subunit;
DE   AltName: Full=Molybdenum cofactor synthesis protein 2B;
DE            Short=MOCS2B;
DE   AltName: Full=Molybdopterin-synthase large subunit;
DE            Short=MPT synthase large subunit;
GN   Name=MOCS2; Synonyms=MCBPE, MOCO1;
DR   GO; GO:0030366; F:molybdopterin synthase activity; IDA:UniProtKB.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MOCOS_HUMAN             Reviewed;         888 AA.
AC   Q96EN8; Q53GP5; Q8N3A4; Q9NWM7;
DE   RecName: Full=Molybdenum cofactor sulfurase;
DE            Short=MCS;
DE            Short=MOS;
DE            Short=MoCo sulfurase;
DE            Short=hMCS;
DE            EC=2.8.1.9;
DE   AltName: Full=Molybdenum cofactor sulfurtransferase;
GN   Name=MOCOS;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008265; F:Mo-molybdopterin cofactor sulfurase activity; IMP:UniProtKB.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0043545; P:molybdopterin cofactor metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MOCS1_HUMAN             Reviewed;         636 AA.
AC   Q9NZB8; B3KPT7; B4DTP1; O14940; O14941; O75710; Q5J7W0; Q5TCE1;
AC   Q5TCE2; Q5TCE6; Q5TCE9; Q5TCF0; Q5TCF1; Q8N418; Q9NZB7; Q9UEM1;
DE   RecName: Full=Molybdenum cofactor biosynthesis protein 1;
DE   AltName: Full=Cell migration-inducing gene 11 protein;
DE   AltName: Full=Molybdenum cofactor synthesis-step 1 protein A-B;
DE   Includes:
DE     RecName: Full=Cyclic pyranopterin monophosphate synthase;
DE              EC=4.1.99.18;
DE     AltName: Full=Molybdenum cofactor biosynthesis protein A;
DE   Includes:
DE     RecName: Full=Cyclic pyranopterin monophosphate synthase accessory protein;
DE     AltName: Full=Molybdenum cofactor biosynthesis protein C;
GN   Name=MOCS1; ORFNames=MIG11;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0061597; F:cyclic pyranopterin monophosphate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MOCS3_HUMAN             Reviewed;         460 AA.
AC   O95396;
DE   RecName: Full=Adenylyltransferase and sulfurtransferase MOCS3;
DE   AltName: Full=Molybdenum cofactor synthesis protein 3;
DE   AltName: Full=Molybdopterin synthase sulfurylase;
DE            Short=MPT synthase sulfurylase;
DE   Includes:
DE     RecName: Full=Molybdopterin-synthase adenylyltransferase;
DE              EC=2.7.7.80;
DE     AltName: Full=Adenylyltransferase MOCS3;
DE     AltName: Full=Sulfur carrier protein MOCS2A adenylyltransferase;
DE   Includes:
DE     RecName: Full=Molybdopterin-synthase sulfurtransferase;
DE              EC=2.8.1.11;
DE     AltName: Full=Sulfur carrier protein MOCS2A sulfurtransferase;
DE     AltName: Full=Sulfurtransferase MOCS3;
GN   Name=MOCS3; Synonyms=UBA4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061605; F:molybdopterin-synthase adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0061604; F:molybdopterin-synthase sulfurtransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016783; F:sulfurtransferase activity; IDA:UniProtKB.
DR   GO; GO:0004792; F:thiosulfate sulfurtransferase activity; IMP:UniProtKB.
DR   GO; GO:0042292; F:URM1 activating enzyme activity; IDA:UniProtKB.
DR   GO; GO:0018192; P:enzyme active site formation via L-cysteine persulfide; IDA:UniProtKB.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034227; P:tRNA thio-modification; IDA:UniProtKB.
DR   GO; GO:0002143; P:tRNA wobble position uridine thiolation; IEA:InterPro.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IDA:UniProtKB.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MOD5_HUMAN              Reviewed;         467 AA.
AC   Q9H3H1; A1A4X7; Q3T7B5; Q5QPK5; Q5QPK6; Q6IAC9; Q96FJ3; Q96L45;
AC   Q9NXT7;
DE   RecName: Full=tRNA dimethylallyltransferase, mitochondrial;
DE            EC=2.5.1.75;
DE   AltName: Full=Isopentenyl-diphosphate:tRNA isopentenyltransferase;
DE            Short=IPP transferase;
DE            Short=IPPT;
DE   AltName: Full=hGRO1;
DE   AltName: Full=tRNA isopentenyltransferase;
DE            Short=IPTase;
DE   Flags: Precursor;
GN   Name=TRIT1; Synonyms=IPT, MOD5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0052381; F:tRNA dimethylallyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   MOES_HUMAN              Reviewed;         577 AA.
AC   P26038;
DE   RecName: Full=Moesin;
DE   AltName: Full=Membrane-organizing extension spike protein;
GN   Name=MSN;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IGI:UniProt.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IEP:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; IEP:BHF-UCL.
DR   GO; GO:0022614; P:membrane to membrane docking; IEP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IGI:UniProt.
DR   GO; GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
//
ID   MOFA1_HUMAN             Reviewed;         127 AA.
AC   Q9Y605; B3KVT2; D3DVT3;
DE   RecName: Full=MORF4 family-associated protein 1;
DE   AltName: Full=Protein PGR1;
DE   AltName: Full=Protein associated with MRG of 14 kDa;
GN   Name=MRFAP1; Synonyms=PAM14, PGR1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   MOG1_HUMAN              Reviewed;         186 AA.
AC   Q9HD47; D3DTR6; Q68DI3; Q9BR68; Q9HD48; Q9NRU9; Q9P001; Q9P0P2;
DE   RecName: Full=Ran guanine nucleotide release factor;
DE            Short=RanGNRF;
DE   AltName: Full=Ran-binding protein MOG1;
GN   Name=RANGRF; Synonyms=MOG1, RANGNRF; ORFNames=HSPC165, HSPC236, MDS5;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0008565; F:protein transporter activity; IMP:BHF-UCL.
DR   GO; GO:0008536; F:Ran GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:BHF-UCL.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:2000010; P:positive regulation of protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:0032527; P:protein exit from endoplasmic reticulum; IMP:BHF-UCL.
DR   GO; GO:0043087; P:regulation of GTPase activity; ISS:GOC.
DR   GO; GO:0002027; P:regulation of heart rate; TAS:BHF-UCL.
DR   GO; GO:0003254; P:regulation of membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:1900825; P:regulation of membrane depolarization during cardiac muscle cell action potential; TAS:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL.
//
ID   MOGS_HUMAN              Reviewed;         837 AA.
AC   Q13724; A8K938; F5H6D0; Q17RN9; Q8TCT5;
DE   RecName: Full=Mannosyl-oligosaccharide glucosidase;
DE            EC=3.2.1.106;
DE   AltName: Full=Processing A-glucosidase I;
GN   Name=MOGS; Synonyms=GCS1;
DR   GO; GO:0015926; F:glucosidase activity; TAS:ProtInc.
DR   GO; GO:0004573; F:mannosyl-oligosaccharide glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IEA:InterPro.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MOGT1_HUMAN             Reviewed;         335 AA.
AC   Q96PD6; Q6IEE5;
DE   RecName: Full=2-acylglycerol O-acyltransferase 1;
DE            EC=2.3.1.22;
DE   AltName: Full=Acyl-CoA:monoacylglycerol acyltransferase 1;
DE            Short=MGAT1;
DE   AltName: Full=Diacylglycerol O-acyltransferase candidate 2;
DE            Short=hDC2;
DE   AltName: Full=Diacylglycerol acyltransferase 2-like protein 1;
DE   AltName: Full=Monoacylglycerol O-acyltransferase 1;
GN   Name=MOGAT1; Synonyms=DC2, DGAT2L1;
DR   GO; GO:0003846; F:2-acylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0006651; P:diacylglycerol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   MOGT2_HUMAN             Reviewed;         334 AA.
AC   Q3SYC2; A8K7I3; Q3SYC1; Q6ZQZ2; Q86UH6; Q9H630;
DE   RecName: Full=2-acylglycerol O-acyltransferase 2;
DE            EC=2.3.1.22;
DE   AltName: Full=Acyl-CoA:monoacylglycerol acyltransferase 2;
DE            Short=MGAT2;
DE            Short=hMGAT2;
DE   AltName: Full=Diacylglycerol O-acyltransferase candidate 5;
DE            Short=hDC5;
DE   AltName: Full=Diacylglycerol acyltransferase 2-like protein 5;
DE   AltName: Full=Monoacylglycerol O-acyltransferase 2;
GN   Name=MOGAT2; Synonyms=DC5, DGAT2L5;
DR   GO; GO:0003846; F:2-acylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016407; F:acetyltransferase activity; IEA:Ensembl.
DR   GO; GO:0006651; P:diacylglycerol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   MOGT3_HUMAN             Reviewed;         341 AA.
AC   Q86VF5; Q496A6; Q496A7; Q496A8; Q9UDW7;
DE   RecName: Full=2-acylglycerol O-acyltransferase 3;
DE            EC=2.3.1.20;
DE            EC=2.3.1.22;
DE   AltName: Full=Acyl-CoA:monoacylglycerol acyltransferase 3;
DE            Short=MGAT3;
DE   AltName: Full=Diacylglycerol O-acyltransferase candidate 7;
DE            Short=hDC7;
DE   AltName: Full=Diacylglycerol acyltransferase 2-like protein 7;
DE   AltName: Full=Monoacylglycerol O-acyltransferase 3;
GN   Name=MOGAT3; Synonyms=DC7, DGAT2L7; ORFNames=UNQ9383/PRO34208;
DR   GO; GO:0003846; F:2-acylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004144; F:diacylglycerol O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   MOG_HUMAN               Reviewed;         247 AA.
AC   Q16653; A6NDR4; A6NNJ9; A8MY31; B0UZR9; E9PGF0; F8W9D5; O00713;
AC   O00714; O00715; Q13054; Q13055; Q14855; Q29ZN8; Q56UY0; Q5JNX7;
AC   Q5JNY1; Q5JNY2; Q5JNY4; Q5SSB5; Q5SSB6; Q5STL9; Q5STM0; Q5STM1;
AC   Q5STM5; Q5SUK7; Q5SUK8; Q5SUK9; Q5SUL0; Q5SUL1; Q92891; Q92892;
AC   Q92893; Q92894; Q92895; Q93053; Q96KU9; Q96KV0; Q96KV1; Q99605;
DE   RecName: Full=Myelin-oligodendrocyte glycoprotein;
DE   Flags: Precursor;
GN   Name=MOG;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0034126; P:positive regulation of MyD88-dependent toll-like receptor signaling pathway; ISS:BHF-UCL.
//
ID   MOK_HUMAN               Reviewed;         419 AA.
AC   Q9UQ07; B2R6Z4; B7Z7P6; E7ER76; E7ERR8; Q92790; Q93067;
DE   RecName: Full=MAPK/MAK/MRK overlapping kinase;
DE            EC=2.7.11.22;
DE   AltName: Full=MOK protein kinase;
DE   AltName: Full=Renal tumor antigen 1;
DE            Short=RAGE-1;
GN   Name=MOK; Synonyms=RAGE, RAGE1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MON1A_HUMAN             Reviewed;         555 AA.
AC   Q86VX9; B2RDQ1; G5E9N1; Q8NAV7; Q9BRF3;
DE   RecName: Full=Vacuolar fusion protein MON1 homolog A;
GN   Name=MON1A; Synonyms=SAND1;
//
ID   MON1B_HUMAN             Reviewed;         547 AA.
AC   Q7L1V2; B4DDZ0; O94949;
DE   RecName: Full=Vacuolar fusion protein MON1 homolog B;
DE   AltName: Full=HSV-1 stimulation-related gene 1 protein;
DE   AltName: Full=HSV-I stimulating-related protein;
GN   Name=MON1B; Synonyms=HSRG1, KIAA0872, SAND2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MON2_HUMAN              Reviewed;        1718 AA.
AC   Q7Z3U7; A5D8U7; A7E2Y0; B9EGP5; Q86TA2; Q8N3I5; Q8NAI0; Q8NHE2;
AC   Q9UPW1;
DE   RecName: Full=Protein MON2 homolog;
DE   AltName: Full=Protein SF21;
GN   Name=MON2; Synonyms=KIAA1040, SF21;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0006895; P:Golgi to endosome transport; ISS:HGNC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:RefGenome.
//
ID   MORC1_HUMAN             Reviewed;         984 AA.
AC   Q86VD1; Q7L8E2; Q9NSG7; Q9Y6D4;
DE   RecName: Full=MORC family CW-type zinc finger protein 1;
DE   AltName: Full=Cancer/testis antigen 33;
DE            Short=CT33;
GN   Name=MORC1; Synonyms=MORC;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   MORC2_HUMAN             Reviewed;        1032 AA.
AC   Q9Y6X9; B2RNB1; Q9UF28; Q9Y6V2;
DE   RecName: Full=MORC family CW-type zinc finger protein 2;
DE   AltName: Full=Zinc finger CW-type coiled-coil domain protein 1;
GN   Name=MORC2; Synonyms=KIAA0852, ZCWCC1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MORC3_HUMAN             Reviewed;         939 AA.
AC   Q14149; A8KA92; Q9UEZ2;
DE   RecName: Full=MORC family CW-type zinc finger protein 3;
DE   AltName: Full=Zinc finger CW-type coiled-coil domain protein 3;
GN   Name=MORC3; Synonyms=KIAA0136, ZCWCC3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007569; P:cell aging; IDA:MGI.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:MGI.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IDA:MGI.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:MGI.
DR   GO; GO:0050821; P:protein stabilization; IDA:MGI.
//
ID   MORN1_HUMAN             Reviewed;         497 AA.
AC   Q5T089; A6NKZ6; Q8WW30; Q9H852;
DE   RecName: Full=MORN repeat-containing protein 1;
GN   Name=MORN1;
//
ID   MORN2_HUMAN             Reviewed;          79 AA.
AC   Q502X0; Q6UL00;
DE   RecName: Full=MORN repeat-containing protein 2;
DE   AltName: Full=MORN motif protein in testis;
GN   Name=MORN2; Synonyms=MOPT;
//
ID   MORC4_HUMAN             Reviewed;         937 AA.
AC   Q8TE76; A1YR23; A1YR24; H7BXF1; Q5JUK7; Q96MZ2; Q9HAI7;
DE   RecName: Full=MORC family CW-type zinc finger protein 4;
DE   AltName: Full=Zinc finger CW-type coiled-coil domain protein 2;
GN   Name=MORC4; Synonyms=ZCWCC2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   MORN3_HUMAN             Reviewed;         240 AA.
AC   Q6PF18; Q86YQ9;
DE   RecName: Full=MORN repeat-containing protein 3;
GN   Name=MORN3;
//
ID   MORN5_HUMAN             Reviewed;         161 AA.
AC   Q5VZ52; Q6ZQN1;
DE   RecName: Full=MORN repeat-containing protein 5;
GN   Name=MORN5; Synonyms=C9orf113, C9orf18;
//
ID   MORN_HUMAN              Reviewed;          11 AA.
AC   P69208; P01163;
DE   RecName: Full=Morphogenetic neuropeptide;
DE   AltName: Full=Head activator;
DE            Short=HA;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   MORN4_HUMAN             Reviewed;         146 AA.
AC   Q8NDC4; Q86Y54;
DE   RecName: Full=MORN repeat-containing protein 4;
DE   AltName: Full=Protein 44050;
GN   Name=MORN4; Synonyms=C10orf83;
//
ID   MOS1_HUMAN              Reviewed;          78 AA.
AC   Q5TGZ0; Q96G68;
DE   RecName: Full=Mitochondrial inner membrane organizing system protein 1;
GN   Name=MINOS1; Synonyms=C1orf151;
//
ID   MOST1_HUMAN             Reviewed;          99 AA.
AC   Q9NRJ1;
DE   RecName: Full=Protein MOST-1;
GN   Name=C8orf17;
//
ID   MOS_HUMAN               Reviewed;         346 AA.
AC   P00540; Q3KPG9; Q3KPH0;
DE   RecName: Full=Proto-oncogene serine/threonine-protein kinase mos;
DE            EC=2.7.11.1;
DE   AltName: Full=Oocyte maturation factor mos;
DE   AltName: Full=Proto-oncogene c-Mos;
GN   Name=MOS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProt.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProt.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:UniProt.
DR   GO; GO:0000186; P:activation of MAPKK activity; ISS:UniProt.
DR   GO; GO:0006325; P:chromatin organization; ISS:UniProt.
DR   GO; GO:0051296; P:establishment of meiotic spindle orientation; ISS:UniProt.
DR   GO; GO:0000165; P:MAPK cascade; ISS:GOC.
DR   GO; GO:0000212; P:meiotic spindle organization; ISS:UniProt.
DR   GO; GO:1902103; P:negative regulation of metaphase/anaphase transition of meiotic cell cycle; ISS:UniProt.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProt.
DR   GO; GO:0040020; P:regulation of meiosis; IEA:Ensembl.
//
ID   MOT10_HUMAN             Reviewed;         515 AA.
AC   Q8TF71; B3KWY0; Q6ZMG0; Q8WVI5;
DE   RecName: Full=Monocarboxylate transporter 10;
DE            Short=MCT 10;
DE   AltName: Full=Aromatic amino acid transporter 1;
DE   AltName: Full=Solute carrier family 16 member 10;
DE   AltName: Full=T-type amino acid transporter 1;
GN   Name=SLC16A10; Synonyms=MCT10, TAT1;
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0015801; P:aromatic amino acid transport; TAS:HGNC.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MOT11_HUMAN             Reviewed;         471 AA.
AC   Q8NCK7;
DE   RecName: Full=Monocarboxylate transporter 11;
DE            Short=MCT 11;
DE   AltName: Full=Solute carrier family 16 member 11;
GN   Name=SLC16A11; Synonyms=MCT11;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IDA:UniProtKB.
//
ID   MOT12_HUMAN             Reviewed;         486 AA.
AC   Q6ZSM3; Q5M9M9; Q5T7J2; Q6ZV76;
DE   RecName: Full=Monocarboxylate transporter 12;
DE            Short=MCT 12;
DE   AltName: Full=Solute carrier family 16 member 12;
GN   Name=SLC16A12; Synonyms=MCT12;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
//
ID   MOT13_HUMAN             Reviewed;         426 AA.
AC   Q7RTY0; A3KMG3; A5PKU5; Q2VP92;
DE   RecName: Full=Monocarboxylate transporter 13;
DE            Short=MCT 13;
DE   AltName: Full=Solute carrier family 16 member 13;
GN   Name=SLC16A13; Synonyms=MCT13;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
//
ID   MOT14_HUMAN             Reviewed;         510 AA.
AC   Q7RTX9; A8KA08; Q53R92; Q96NI7;
DE   RecName: Full=Monocarboxylate transporter 14;
DE            Short=MCT 14;
DE   AltName: Full=Solute carrier family 16 member 14;
GN   Name=SLC16A14; Synonyms=MCT14;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
//
ID   MOT1_HUMAN              Reviewed;         500 AA.
AC   P53985; Q5T8R6; Q9NSJ9;
DE   RecName: Full=Monocarboxylate transporter 1;
DE            Short=MCT 1;
DE   AltName: Full=Solute carrier family 16 member 1;
GN   Name=SLC16A1; Synonyms=MCT1;
DR   GO; GO:0015130; F:mevalonate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0097159; F:organic cyclic compound binding; IEA:Ensembl.
DR   GO; GO:0015355; F:secondary active monocarboxylate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0015728; P:mevalonate transport; TAS:ProtInc.
DR   GO; GO:0015718; P:monocarboxylic acid transport; TAS:ProtInc.
DR   GO; GO:0035879; P:plasma membrane lactate transport; ISS:UniProtKB.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MOT2_HUMAN              Reviewed;         478 AA.
AC   O60669; Q8NEM3; Q9UPB3;
DE   RecName: Full=Monocarboxylate transporter 2;
DE            Short=MCT 2;
DE   AltName: Full=Solute carrier family 16 member 7;
GN   Name=SLC16A7; Synonyms=MCT2;
DR   GO; GO:0015129; F:lactate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005477; F:pyruvate secondary active transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0050833; F:pyruvate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015355; F:secondary active monocarboxylate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0035873; P:lactate transmembrane transport; IMP:UniProtKB.
DR   GO; GO:1901475; P:pyruvate transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MOT3_HUMAN              Reviewed;         504 AA.
AC   O95907; Q9UBE2;
DE   RecName: Full=Monocarboxylate transporter 3;
DE            Short=MCT 3;
DE   AltName: Full=Solute carrier family 16 member 8;
GN   Name=SLC16A8; Synonyms=MCT3;
DR   GO; GO:0015129; F:lactate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015355; F:secondary active monocarboxylate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0035873; P:lactate transmembrane transport; TAS:GOC.
DR   GO; GO:0015727; P:lactate transport; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MOT4_HUMAN              Reviewed;         465 AA.
AC   O15427; B3KXG8; Q2M1P8;
DE   RecName: Full=Monocarboxylate transporter 4;
DE            Short=MCT 4;
DE   AltName: Full=Solute carrier family 16 member 3;
GN   Name=SLC16A3; Synonyms=MCT4;
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0015355; F:secondary active monocarboxylate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0015718; P:monocarboxylic acid transport; TAS:ProtInc.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MOT5_HUMAN              Reviewed;         487 AA.
AC   O15374; A8K3V5; B2R9C9; B4DJ67; B4DPX7; E7EPY8; G3V175; Q5T612;
AC   Q8WU09;
DE   RecName: Full=Monocarboxylate transporter 5;
DE            Short=MCT 5;
DE   AltName: Full=Monocarboxylate transporter 4;
DE            Short=MCT 4;
DE   AltName: Full=Solute carrier family 16 member 4;
GN   Name=SLC16A4; Synonyms=MCT4, MCT5;
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015718; P:monocarboxylic acid transport; TAS:ProtInc.
//
ID   MOT6_HUMAN              Reviewed;         505 AA.
AC   O15375;
DE   RecName: Full=Monocarboxylate transporter 6;
DE            Short=MCT 6;
DE   AltName: Full=Monocarboxylate transporter 5;
DE            Short=MCT 5;
DE   AltName: Full=Solute carrier family 16 member 5;
GN   Name=SLC16A5; Synonyms=MCT5, MCT6;
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015355; F:secondary active monocarboxylate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015718; P:monocarboxylic acid transport; TAS:ProtInc.
//
ID   MOT7_HUMAN              Reviewed;         523 AA.
AC   O15403; Q6P1X3;
DE   RecName: Full=Monocarboxylate transporter 7;
DE            Short=MCT 7;
DE   AltName: Full=Monocarboxylate transporter 6;
DE            Short=MCT 6;
DE   AltName: Full=Solute carrier family 16 member 6;
GN   Name=SLC16A6; Synonyms=MCT6, MCT7;
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015718; P:monocarboxylic acid transport; TAS:ProtInc.
//
ID   MOT8_HUMAN              Reviewed;         539 AA.
AC   P36021; Q7Z797;
DE   RecName: Full=Monocarboxylate transporter 8;
DE            Short=MCT 8;
DE   AltName: Full=Monocarboxylate transporter 7;
DE            Short=MCT 7;
DE   AltName: Full=Solute carrier family 16 member 2;
DE   AltName: Full=X-linked PEST-containing transporter;
GN   Name=SLC16A2; Synonyms=MCT8, XPCT;
DR   GO; GO:0008028; F:monocarboxylic acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015718; P:monocarboxylic acid transport; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MOT9_HUMAN              Reviewed;         509 AA.
AC   Q7RTY1; Q6ZMI2; Q9UFH8;
DE   RecName: Full=Monocarboxylate transporter 9;
DE            Short=MCT 9;
DE   AltName: Full=Solute carrier family 16 member 9;
GN   Name=SLC16A9; Synonyms=C10orf36, MCT9;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0046415; P:urate metabolic process; IMP:BHF-UCL.
//
ID   MOTI_HUMAN              Reviewed;         115 AA.
AC   P12872; B7ZLR7; E9PDN2; J3KN51; Q2M1L2; Q5T975; Q6NSY7;
DE   RecName: Full=Promotilin;
DE   Contains:
DE     RecName: Full=Motilin;
DE   Contains:
DE     RecName: Full=Motilin-associated peptide;
DE              Short=MAP;
DE   Flags: Precursor;
GN   Name=MLN;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   MOV10_HUMAN             Reviewed;        1003 AA.
AC   Q9HCE1; Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9;
DE   RecName: Full=Putative helicase MOV-10;
DE            EC=3.6.4.13;
DE   AltName: Full=Moloney leukemia virus 10 protein;
GN   Name=MOV10; Synonyms=KIAA1631;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035279; P:mRNA cleavage involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MOXD1_HUMAN             Reviewed;         613 AA.
AC   Q6UVY6; Q5THU6; Q8NC97; Q8WV49; Q9H4M6; Q9Y4U3;
DE   RecName: Full=DBH-like monooxygenase protein 1;
DE            EC=1.14.17.-;
DE   AltName: Full=Monooxygenase X;
DE   Flags: Precursor;
GN   Name=MOXD1; Synonyms=MOX; ORFNames=UNQ2493/PRO5780;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016715; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
//
ID   MOXD2_HUMAN             Reviewed;         499 AA.
AC   A6NHM9;
DE   RecName: Full=Putative DBH-like monooxygenase protein 2;
DE            EC=1.14.17.-;
DE   AltName: Full=DBH-like monooxygenase protein 2 pseudogene;
DE   Flags: Precursor;
GN   Name=MOXD2P; Synonyms=MOXD2;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016715; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
//
ID   MP17L_HUMAN             Reviewed;         196 AA.
AC   Q2QL34; B4DDY1; Q6P7T6; Q8N8E9;
DE   RecName: Full=Mpv17-like protein;
DE   AltName: Full=M-LP homolog;
DE            Short=M-LPH;
GN   Name=MPV17L;
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0010730; P:negative regulation of hydrogen peroxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
//
ID   MP2K1_HUMAN             Reviewed;         393 AA.
AC   Q02750;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 1;
DE            Short=MAP kinase kinase 1;
DE            Short=MAPKK 1;
DE            Short=MKK1;
DE            EC=2.7.12.2;
DE   AltName: Full=ERK activator kinase 1;
DE   AltName: Full=MAPK/ERK kinase 1;
DE            Short=MEK 1;
GN   Name=MAP2K1; Synonyms=MEK1, PRKMK1;
DR   GuidetoPHARMACOLOGY; 2062; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0048870; P:cell motility; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0090398; P:cellular senescence; IMP:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048313; P:Golgi inheritance; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0032402; P:melanosome transport; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0034111; P:negative regulation of homotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProt.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.
DR   GO; GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0003056; P:regulation of vascular smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IEA:Ensembl.
//
ID   MP2K2_HUMAN             Reviewed;         400 AA.
AC   P36507;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 2;
DE            Short=MAP kinase kinase 2;
DE            Short=MAPKK 2;
DE            EC=2.7.12.2;
DE   AltName: Full=ERK activator kinase 2;
DE   AltName: Full=MAPK/ERK kinase 2;
DE            Short=MEK 2;
GN   Name=MAP2K2; Synonyms=MEK2, MKK2, PRKMK2;
DR   GuidetoPHARMACOLOGY; 2063; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0036289; P:peptidyl-serine autophosphorylation; IDA:UniProtKB.
DR   GO; GO:2000147; P:positive regulation of cell motility; IEA:Ensembl.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.
DR   GO; GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MP2K3_HUMAN             Reviewed;         347 AA.
AC   P46734; B3KSK7; Q99441; Q9UE71; Q9UE72;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3;
DE            Short=MAP kinase kinase 3;
DE            Short=MAPKK 3;
DE            EC=2.7.12.2;
DE   AltName: Full=MAPK/ERK kinase 3;
DE            Short=MEK 3;
DE   AltName: Full=Stress-activated protein kinase kinase 2;
DE            Short=SAPK kinase 2;
DE            Short=SAPKK-2;
DE            Short=SAPKK2;
GN   Name=MAP2K3; Synonyms=MEK3, MKK3, PRKMK3, SKK2;
DR   GuidetoPHARMACOLOGY; 2064; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MP2K4_HUMAN             Reviewed;         399 AA.
AC   P45985; B2R7N7; B3KYB2; D3DTS5; Q5U0B8; Q6FHX4; Q6P9H2; Q6PIE6;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 4;
DE            Short=MAP kinase kinase 4;
DE            Short=MAPKK 4;
DE            EC=2.7.12.2;
DE   AltName: Full=JNK-activating kinase 1;
DE   AltName: Full=MAPK/ERK kinase 4;
DE            Short=MEK 4;
DE   AltName: Full=SAPK/ERK kinase 1;
DE            Short=SEK1;
DE   AltName: Full=Stress-activated protein kinase kinase 1;
DE            Short=SAPK kinase 1;
DE            Short=SAPKK-1;
DE            Short=SAPKK1;
DE   AltName: Full=c-Jun N-terminal kinase kinase 1;
DE            Short=JNKK;
GN   Name=MAP2K4; Synonyms=JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1;
DR   GuidetoPHARMACOLOGY; 2065; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008545; F:JUN kinase kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0072709; P:cellular response to sorbitol; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MP2K5_HUMAN             Reviewed;         448 AA.
AC   Q13163; B4DE43; Q92961; Q92962;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 5;
DE            Short=MAP kinase kinase 5;
DE            Short=MAPKK 5;
DE            EC=2.7.12.2;
DE   AltName: Full=MAPK/ERK kinase 5;
DE            Short=MEK 5;
GN   Name=MAP2K5; Synonyms=MEK5, MKK5, PRKMK5;
DR   GuidetoPHARMACOLOGY; 2066; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; ISS:BHF-UCL.
DR   GO; GO:0071499; P:cellular response to laminar fluid shear stress; TAS:BHF-UCL.
DR   GO; GO:0070375; P:ERK5 cascade; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.
DR   GO; GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; ISS:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; ISS:BHF-UCL.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0060761; P:negative regulation of response to cytokine stimulus; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0051247; P:positive regulation of protein metabolic process; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MP2K6_HUMAN             Reviewed;         334 AA.
AC   P52564;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6;
DE            Short=MAP kinase kinase 6;
DE            Short=MAPKK 6;
DE            EC=2.7.12.2;
DE   AltName: Full=MAPK/ERK kinase 6;
DE            Short=MEK 6;
DE   AltName: Full=Stress-activated protein kinase kinase 3;
DE            Short=SAPK kinase 3;
DE            Short=SAPKK-3;
DE            Short=SAPKK3;
GN   Name=MAP2K6; Synonyms=MEK6, MKK6, PRKMK6, SKK3;
DR   GuidetoPHARMACOLOGY; 2067; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0072709; P:cellular response to sorbitol; IEA:Ensembl.
DR   GO; GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MP2K7_HUMAN             Reviewed;         419 AA.
AC   O14733; B2R9S5; D6W659; O14648; O14816; O60452; O60453; Q1PG43;
AC   Q8IY10;
DE   RecName: Full=Dual specificity mitogen-activated protein kinase kinase 7;
DE            Short=MAP kinase kinase 7;
DE            Short=MAPKK 7;
DE            EC=2.7.12.2;
DE   AltName: Full=JNK-activating kinase 2;
DE   AltName: Full=MAPK/ERK kinase 7;
DE            Short=MEK 7;
DE   AltName: Full=Stress-activated protein kinase kinase 4;
DE            Short=SAPK kinase 4;
DE            Short=SAPKK-4;
DE            Short=SAPKK4;
DE   AltName: Full=c-Jun N-terminal kinase kinase 2;
DE            Short=JNK kinase 2;
DE            Short=JNKK 2;
GN   Name=MAP2K7; Synonyms=JNKK2, MEK7, MKK7, PRKMK7, SKK4;
DR   GuidetoPHARMACOLOGY; 2068; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008545; F:JUN kinase kinase activity; IEA:Ensembl.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; ISS:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007257; P:activation of JUN kinase activity; ISS:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0072709; P:cellular response to sorbitol; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   MP3B2_HUMAN             Reviewed;         125 AA.
AC   A6NCE7;
DE   RecName: Full=Microtubule-associated proteins 1A/1B light chain 3 beta 2;
DE   AltName: Full=Microtubule-associated proteins 1A/1B light chain 3B-like;
DE   Flags: Precursor;
GN   Name=MAP1LC3B2;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   MPC1L_HUMAN             Reviewed;         136 AA.
AC   P0DKB6;
DE   RecName: Full=Mitochondrial pyruvate carrier 1-like protein;
GN   Name=MPC1L;
DR   GO; GO:0006850; P:mitochondrial pyruvate transport; IEA:InterPro.
//
ID   MPC1_HUMAN              Reviewed;         109 AA.
AC   Q9Y5U8; B2R5I7; Q5TI66; Q9HB67; Q9UQN4;
DE   RecName: Full=Mitochondrial pyruvate carrier 1;
DE   AltName: Full=Brain protein 44-like protein;
GN   Name=MPC1; Synonyms=BRP44L; ORFNames=CGI-129, HSPC040, PNAS-115;
DR   GO; GO:0050833; F:pyruvate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006850; P:mitochondrial pyruvate transport; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MPC2_HUMAN              Reviewed;         127 AA.
AC   O95563; A8K261; Q3SXR6; Q6FIF3;
DE   RecName: Full=Mitochondrial pyruvate carrier 2;
DE   AltName: Full=Brain protein 44;
GN   Name=MPC2; Synonyms=BRP44;
DR   GO; GO:0050833; F:pyruvate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006850; P:mitochondrial pyruvate transport; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MPCP_HUMAN              Reviewed;         362 AA.
AC   Q00325; B3KS34; Q7Z7N7; Q96A03;
DE   RecName: Full=Phosphate carrier protein, mitochondrial;
DE   AltName: Full=Phosphate transport protein;
DE            Short=PTP;
DE   AltName: Full=Solute carrier family 25 member 3;
DE   Flags: Precursor;
GN   Name=SLC25A3; Synonyms=PHC; ORFNames=OK/SW-cl.48;
DR   GO; GO:0015320; F:phosphate ion carrier activity; TAS:ProtInc.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MPDZ_HUMAN              Reviewed;        2070 AA.
AC   O75970; A6NLC2; B2RTS3; B7ZMI4; O43798; Q4LE30; Q5CZ80; Q5JTX3;
AC   Q5JTX6; Q5JTX7; Q5JUC3; Q5JUC4; Q5VZ62; Q8N790;
DE   RecName: Full=Multiple PDZ domain protein;
DE   AltName: Full=Multi-PDZ domain protein 1;
GN   Name=MPDZ; Synonyms=MUPP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MPEG1_HUMAN             Reviewed;         716 AA.
AC   Q2M385; Q2M1T6; Q8TEF8;
DE   RecName: Full=Macrophage-expressed gene 1 protein;
DE            Short=Macrophage gene 1 protein;
DE            Short=Mpg-1;
DE   Flags: Precursor;
GN   Name=MPEG1;
//
ID   MPH6_HUMAN              Reviewed;         160 AA.
AC   Q99547; B2RAF0;
DE   RecName: Full=M-phase phosphoprotein 6;
GN   Name=MPHOSPH6; Synonyms=MPP6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
DR   GO; GO:0000087; P:mitotic M phase; TAS:ProtInc.
//
ID   MPIP1_HUMAN             Reviewed;         524 AA.
AC   P30304; Q8IZH5; Q96IL3; Q9H2F2;
DE   RecName: Full=M-phase inducer phosphatase 1;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase Cdc25A;
GN   Name=CDC25A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; IDA:UniProtKB.
//
ID   MPIP2_HUMAN             Reviewed;         580 AA.
AC   P30305; D3DVY1; D3DVY2; D3DVY3; D3DVY4; O43551; Q13971; Q5JX77;
AC   Q6RSS1; Q9BRA6;
DE   RecName: Full=M-phase inducer phosphatase 2;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase Cdc25B;
GN   Name=CDC25B; Synonyms=CDC25HU2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.
DR   GO; GO:0007144; P:female meiosis I; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   MPIP3_HUMAN             Reviewed;         473 AA.
AC   P30307; D3DQB8; Q96PL3; Q9H168; Q9H2E8; Q9H2E9; Q9H2F1;
DE   RecName: Full=M-phase inducer phosphatase 3;
DE            EC=3.1.3.48;
DE   AltName: Full=Dual specificity phosphatase Cdc25C;
GN   Name=CDC25C;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IPI:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; NAS:GOC.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   MPI_HUMAN               Reviewed;         423 AA.
AC   P34949; A8K8K9; Q96AB0;
DE   RecName: Full=Mannose-6-phosphate isomerase;
DE            EC=5.3.1.8;
DE   AltName: Full=Phosphohexomutase;
DE   AltName: Full=Phosphomannose isomerase;
DE            Short=PMI;
GN   Name=MPI; Synonyms=PMI1;
DR   GO; GO:0004476; F:mannose-6-phosphate isomerase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   MPLKI_HUMAN             Reviewed;         179 AA.
AC   Q8TAP9;
DE   RecName: Full=M-phase-specific PLK1-interacting protein;
DE   AltName: Full=TTD non-photosensitive 1 protein;
GN   Name=MPLKIP; Synonyms=C7orf11, TTDN1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   MPND_HUMAN              Reviewed;         471 AA.
AC   Q8N594; Q96SJ0; Q9Y2P1; Q9Y2P2;
DE   RecName: Full=MPN domain-containing protein;
DE            EC=3.4.-.-;
GN   Name=MPND;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
//
ID   MPP10_HUMAN             Reviewed;         681 AA.
AC   O00566; A0AVJ8;
DE   RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10;
DE   AltName: Full=M phase phosphoprotein 10;
GN   Name=MPHOSPH10; Synonyms=MPP10;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; NAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; NAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; NAS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   MPP2_HUMAN              Reviewed;         576 AA.
AC   Q14168; Q53ES9; Q5CZB9; Q9BQJ2;
DE   RecName: Full=MAGUK p55 subfamily member 2;
DE   AltName: Full=Discs large homolog 2;
DE   AltName: Full=Protein MPP2;
GN   Name=MPP2; Synonyms=DLG2;
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MPP3_HUMAN              Reviewed;         585 AA.
AC   Q13368; B2R7N0; D3DX47; Q4GX05; Q6PGR3; Q86SV1;
DE   RecName: Full=MAGUK p55 subfamily member 3;
DE   AltName: Full=Discs large homolog 3;
DE   AltName: Full=Protein MPP3;
GN   Name=MPP3; Synonyms=DLG3;
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MPP4_HUMAN              Reviewed;         637 AA.
AC   Q96JB8; C9IZK4; Q53TT3; Q6ZNH6; Q96Q43; Q96Q44;
DE   RecName: Full=MAGUK p55 subfamily member 4;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein;
DE   AltName: Full=Discs large homolog 6;
GN   Name=MPP4; Synonyms=ALS2CR5, DLG6;
DR   GO; GO:0035418; P:protein localization to synapse; IEA:Ensembl.
//
ID   MPP5_HUMAN              Reviewed;         675 AA.
AC   Q8N3R9; A1L380; Q7Z631; Q86T98; Q8N7I5; Q9H9Q0;
DE   RecName: Full=MAGUK p55 subfamily member 5;
GN   Name=MPP5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0032288; P:myelin assembly; IEA:Ensembl.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:0035750; P:protein localization to myelin sheath abaxonal region; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   MPP6_HUMAN              Reviewed;         540 AA.
AC   Q9NZW5; A4D157; Q9H0E1;
DE   RecName: Full=MAGUK p55 subfamily member 6;
DE   AltName: Full=Veli-associated MAGUK 1;
DE            Short=VAM-1;
GN   Name=MPP6; Synonyms=VAM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
//
ID   MPP7_HUMAN              Reviewed;         576 AA.
AC   Q5T2T1; B2RCC9; B5MDZ3; D3DRW3; Q5T2T0; Q8IY28;
DE   RecName: Full=MAGUK p55 subfamily member 7;
GN   Name=MPP7;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0035591; F:signaling adaptor activity; NAS:BHF-UCL.
DR   GO; GO:0030010; P:establishment of cell polarity; TAS:BHF-UCL.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; NAS:GOC.
DR   GO; GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.
DR   GO; GO:0070830; P:tight junction assembly; IDA:BHF-UCL.
//
ID   MPP9_HUMAN              Reviewed;        1031 AA.
AC   Q99550; A1L486; A6NEE2; B3KR87; Q9H976;
DE   RecName: Full=M-phase phosphoprotein 9;
GN   Name=MPHOSPH9; Synonyms=MPP9;
DR   GO; GO:0000087; P:mitotic M phase; TAS:ProtInc.
//
ID   MPP8_HUMAN              Reviewed;         860 AA.
AC   Q99549; B7Z6F9; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q9BTP1;
DE   RecName: Full=M-phase phosphoprotein 8;
DE   AltName: Full=Two hybrid-associated protein 3 with RanBPM;
DE            Short=Twa3;
GN   Name=MPHOSPH8; Synonyms=MPP8;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0044030; P:regulation of DNA methylation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MPPA_HUMAN              Reviewed;         525 AA.
AC   Q10713; B4DKL3; E7ET61; Q16639; Q5SXM9; Q8N513;
DE   RecName: Full=Mitochondrial-processing peptidase subunit alpha;
DE            EC=3.4.24.64;
DE   AltName: Full=Alpha-MPP;
DE   AltName: Full=P-55;
DE   Flags: Precursor;
GN   Name=PMPCA; Synonyms=INPP5E, KIAA0123, MPPA;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:UniProtKB.
//
ID   MPPD1_HUMAN             Reviewed;         326 AA.
AC   O15442; A8K159; Q8N361;
DE   RecName: Full=Metallophosphoesterase domain-containing protein 1;
DE            EC=3.1.-.-;
DE   AltName: Full=Adult brain protein 239;
DE            Short=239AB;
GN   Name=MPPED1; Synonyms=C22orf1, FAM1A;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   MPPB_HUMAN              Reviewed;         489 AA.
AC   O75439; O60416; Q96FV4;
DE   RecName: Full=Mitochondrial-processing peptidase subunit beta;
DE            EC=3.4.24.64;
DE   AltName: Full=Beta-MPP;
DE   AltName: Full=P-52;
DE   Flags: Precursor;
GN   Name=PMPCB; Synonyms=MPPB;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   MPPD2_HUMAN             Reviewed;         294 AA.
AC   Q15777; D3DQZ5; E9PB10; Q59GE6;
DE   RecName: Full=Metallophosphoesterase MPPED2;
DE            EC=3.1.-.-;
DE   AltName: Full=Fetal brain protein 239;
DE            Short=239FB;
DE   AltName: Full=Metallophosphoesterase domain-containing protein 2;
GN   Name=MPPED2; Synonyms=C11orf8, FAM1B;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   MPPE1_HUMAN             Reviewed;         396 AA.
AC   Q53F39; B0YJ39; B0YJ40; B0YJ41; B5ME53; B7WNJ3; D3DUI5; D3DUI7;
AC   Q6GMP1; Q8TAD6; Q8TE26; Q8WZ32; Q9BU58; Q9H958; Q9HAI4;
DE   RecName: Full=Metallophosphoesterase 1;
DE            EC=3.1.-.-;
DE   AltName: Full=Post-GPI attachment to proteins factor 5;
GN   Name=MPPE1; Synonyms=PGAP5; ORFNames=PP579;
DR   GO; GO:0034235; F:GPI anchor binding; ISS:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; ISS:UniProtKB.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; ISS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; ISS:UniProtKB.
//
ID   MPRA_HUMAN              Reviewed;         346 AA.
AC   Q86WK9; A2A2D3; Q5XKF9; Q86VE4;
DE   RecName: Full=Membrane progestin receptor alpha;
DE            Short=mPR alpha;
DE   AltName: Full=Progestin and adipoQ receptor family member 7;
DE   AltName: Full=Progestin and adipoQ receptor family member VII;
GN   Name=PAQR7; Synonyms=MRPA;
DR   GO; GO:0005496; F:steroid binding; IBA:RefGenome.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0048545; P:response to steroid hormone; IBA:RefGenome.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IBA:GOC.
//
ID   MPRB_HUMAN              Reviewed;         354 AA.
AC   Q8TEZ7; B2RCF6; Q86WL0; Q8N6D3; Q9HD02;
DE   RecName: Full=Membrane progestin receptor beta;
DE            Short=mPR beta;
DE   AltName: Full=Lysosomal membrane protein in brain 1;
DE   AltName: Full=Progestin and adipoQ receptor family member 8;
DE   AltName: Full=Progestin and adipoQ receptor family member VIII;
GN   Name=PAQR8; Synonyms=C6orf33, LMPB1, MPRB;
DR   GO; GO:0005496; F:steroid binding; IBA:RefGenome.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0048545; P:response to steroid hormone; IBA:RefGenome.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IBA:GOC.
//
ID   MPRD_HUMAN              Reviewed;         277 AA.
AC   P20645; A8K528; D3DUV5;
DE   RecName: Full=Cation-dependent mannose-6-phosphate receptor;
DE            Short=CD Man-6-P receptor;
DE            Short=CD-MPR;
DE   AltName: Full=46 kDa mannose 6-phosphate receptor;
DE            Short=MPR 46;
DE   Flags: Precursor;
GN   Name=M6PR; Synonyms=MPR46, MPRD;
DR   GO; GO:0005537; F:mannose binding; IEA:InterPro.
DR   GO; GO:0015578; F:mannose transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0008333; P:endosome to lysosome transport; TAS:ProtInc.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   MPRG_HUMAN              Reviewed;         330 AA.
AC   Q9NXK6; Q8IXU2;
DE   RecName: Full=Membrane progestin receptor gamma;
DE            Short=mPR gamma;
DE   AltName: Full=Progestin and adipoQ receptor family member 5;
DE   AltName: Full=Progestin and adipoQ receptor family member V;
GN   Name=PAQR5; Synonyms=MPRG;
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
//
ID   MPRIP_HUMAN             Reviewed;        1025 AA.
AC   Q6WCQ1; Q3KQZ5; Q5FB94; Q6DHW2; Q7Z5Y2; Q8N390; Q96G40;
DE   RecName: Full=Myosin phosphatase Rho-interacting protein;
DE            Short=M-RIP;
DE   AltName: Full=Rho-interacting protein 3;
DE            Short=RIP3;
DE   AltName: Full=p116Rip;
GN   Name=MPRIP; Synonyms=KIAA0864, MRIP, RHOIP3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MPRI_HUMAN              Reviewed;        2491 AA.
AC   P11717; Q7Z7G9; Q96PT5;
DE   RecName: Full=Cation-independent mannose-6-phosphate receptor;
DE            Short=CI Man-6-P receptor;
DE            Short=CI-MPR;
DE            Short=M6PR;
DE   AltName: Full=300 kDa mannose 6-phosphate receptor;
DE            Short=MPR 300;
DE   AltName: Full=Insulin-like growth factor 2 receptor;
DE   AltName: Full=Insulin-like growth factor II receptor;
DE            Short=IGF-II receptor;
DE   AltName: Full=M6P/IGF2 receptor;
DE            Short=M6P/IGF2R;
DE   AltName: CD_antigen=CD222;
DE   Flags: Precursor;
GN   Name=IGF2R; Synonyms=MPRI;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:Ensembl.
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005010; F:insulin-like growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0005537; F:mannose binding; IEA:Ensembl.
DR   GO; GO:0051219; F:phosphoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0001972; F:retinoic acid binding; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; TAS:GOC.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   MPTX_HUMAN              Reviewed;         137 AA.
AC   A8MV57;
DE   RecName: Full=Putative mucosal pentraxin homolog;
GN   Name=MPTX1; Synonyms=MPTX;
//
ID   MPU1_HUMAN              Reviewed;         247 AA.
AC   O75352; B3KQP1; Q9BUU8;
DE   RecName: Full=Mannose-P-dolichol utilization defect 1 protein;
DE   AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog;
DE            Short=SL15;
GN   Name=MPDU1;
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MPZL1_HUMAN             Reviewed;         269 AA.
AC   O95297; B2REB9; B2REC0; Q5R332; Q8IX11; Q9BWZ3; Q9NYK4; Q9UL20;
DE   RecName: Full=Myelin protein zero-like protein 1;
DE   AltName: Full=Protein zero-related;
DE   Flags: Precursor;
GN   Name=MPZL1; Synonyms=PZR; ORFNames=UNQ849/PRO1787;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   MPV17_HUMAN             Reviewed;         176 AA.
AC   P39210; D6W555; Q53SY2; Q96B08;
DE   RecName: Full=Protein Mpv17;
GN   Name=MPV17;
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; ISS:UniProtKB.
DR   GO; GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; IMP:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; ISS:UniProtKB.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IMP:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; ISS:UniProtKB.
//
ID   MPZL3_HUMAN             Reviewed;         235 AA.
AC   Q6UWV2; A8K025; B4E2I8;
DE   RecName: Full=Myelin protein zero-like protein 3;
DE   Flags: Precursor;
GN   Name=MPZL3; ORFNames=UNQ2966/PRO7425;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0042633; P:hair cycle; IEA:Ensembl.
//
ID   MPZL2_HUMAN             Reviewed;         215 AA.
AC   O60487; A8K2R1;
DE   RecName: Full=Myelin protein zero-like protein 2;
DE   AltName: Full=Epithelial V-like antigen 1;
DE   Flags: Precursor;
GN   Name=MPZL2; Synonyms=EVA, EVA1; ORFNames=UNQ606/PRO1192;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
//
ID   MR1L1_HUMAN             Reviewed;         127 AA.
AC   Q96HT8; B2R6R0; Q6NXT8; Q9P0J5;
DE   RecName: Full=MORF4 family-associated protein 1-like 1;
GN   Name=MRFAP1L1; ORFNames=PP784;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MRAP_HUMAN              Reviewed;         172 AA.
AC   Q8TCY5; Q5EBR3; Q8TDB7; Q8WXC1; Q8WXC2;
DE   RecName: Full=Melanocortin-2 receptor accessory protein;
DE   AltName: Full=B27;
DE   AltName: Full=Fat cell-specific low molecular weight protein;
DE   AltName: Full=Fat tissue-specific low MW protein;
GN   Name=MRAP; Synonyms=C21orf61, FALP;
DR   GO; GO:0031780; F:corticotropin hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0070996; F:type 1 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031781; F:type 3 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031782; F:type 4 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031783; F:type 5 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:BHF-UCL.
//
ID   MRAP2_HUMAN             Reviewed;         205 AA.
AC   Q96G30; A8K9M1; Q8IXM9; Q8N2D1;
DE   RecName: Full=Melanocortin-2 receptor accessory protein 2;
DE            Short=MC2R accessory protein 2;
GN   Name=MRAP2; Synonyms=C6orf117;
DR   GO; GO:0031780; F:corticotropin hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0070996; F:type 1 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031781; F:type 3 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031782; F:type 4 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031783; F:type 5 melanocortin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0097009; P:energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; ISS:UniProtKB.
DR   GO; GO:0007631; P:feeding behavior; ISS:UniProtKB.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:BHF-UCL.
//
ID   MRAS1_HUMAN             Reviewed;         158 AA.
AC   Q2M3A8; Q6TF48; Q8N7R8; Q8N9X7;
DE   RecName: Full=Putative uncharacterized protein MRGPRG-AS1;
DE   AltName: Full=MRGPRG antisense RNA 1;
DE   AltName: Full=MRGPRG antisense gene protein 1;
GN   Name=MRGPRG-AS1; Synonyms=C11orf36; ORFNames=HSD-40, HSD40;
//
ID   MRC1_HUMAN              Reviewed;        1456 AA.
AC   P22897; A5PKW3; Q5VSJ2; Q5VSK2;
DE   RecName: Full=Macrophage mannose receptor 1;
DE            Short=MMR;
DE   AltName: Full=C-type lectin domain family 13 member D;
DE   AltName: Full=C-type lectin domain family 13 member D-like;
DE   AltName: Full=Macrophage mannose receptor 1-like protein 1;
DE   AltName: CD_antigen=CD206;
DE   Flags: Precursor;
GN   Name=MRC1; Synonyms=CLEC13D, CLEC13DL, MRC1L1;
DR   GO; GO:0005537; F:mannose binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:MTBBASE.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:UniProtKB.
//
ID   MRC2_HUMAN              Reviewed;        1479 AA.
AC   Q9UBG0; A6H8K4; D3DU08; Q7LGE7; Q9Y5P9;
DE   RecName: Full=C-type mannose receptor 2;
DE   AltName: Full=C-type lectin domain family 13 member E;
DE   AltName: Full=Endocytic receptor 180;
DE   AltName: Full=Macrophage mannose receptor 2;
DE   AltName: Full=Urokinase-type plasminogen activator receptor-associated protein;
DE            Short=UPAR-associated protein;
DE            Short=Urokinase receptor-associated protein;
DE   AltName: CD_antigen=CD280;
DE   Flags: Precursor;
GN   Name=MRC2; Synonyms=CLEC13E, ENDO180, KIAA0709, UPARAP;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:UniProt.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
//
ID   MRCKA_HUMAN             Reviewed;        1732 AA.
AC   Q5VT25; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT26; Q5VT27; Q86XX2;
AC   Q86XX3; Q99646;
DE   RecName: Full=Serine/threonine-protein kinase MRCK alpha;
DE            EC=2.7.11.1;
DE   AltName: Full=CDC42-binding protein kinase alpha;
DE   AltName: Full=DMPK-like alpha;
DE   AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase alpha;
DE            Short=MRCK alpha;
DE            Short=Myotonic dystrophy protein kinase-like alpha;
GN   Name=CDC42BPA; Synonyms=KIAA0451;
DR   GuidetoPHARMACOLOGY; 1507; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007097; P:nuclear migration; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   MRCKB_HUMAN             Reviewed;        1711 AA.
AC   Q9Y5S2; A9JR72; Q2L7A5; Q86TJ1; Q9ULU5;
DE   RecName: Full=Serine/threonine-protein kinase MRCK beta;
DE            EC=2.7.11.1;
DE   AltName: Full=CDC42-binding protein kinase beta;
DE            Short=CDC42BP-beta;
DE   AltName: Full=DMPK-like beta;
DE   AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase beta;
DE            Short=MRCK beta;
DE            Short=Myotonic dystrophy protein kinase-like beta;
GN   Name=CDC42BPB; Synonyms=KIAA1124;
DR   GuidetoPHARMACOLOGY; 1508; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MRCKG_HUMAN             Reviewed;        1551 AA.
AC   Q6DT37; O00565;
DE   RecName: Full=Serine/threonine-protein kinase MRCK gamma;
DE            EC=2.7.11.1;
DE   AltName: Full=CDC42-binding protein kinase gamma;
DE   AltName: Full=DMPK-like gamma;
DE   AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase gamma;
DE            Short=MRCK gamma;
DE            Short=MRCKG;
DE            Short=Myotonic dystrophy protein kinase-like gamma;
DE   AltName: Full=Myotonic dystrophy protein kinase-like alpha;
GN   Name=CDC42BPG; Synonyms=DMPK2;
DR   GuidetoPHARMACOLOGY; 1506; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   MRE11_HUMAN             Reviewed;         708 AA.
AC   P49959; O43475;
DE   RecName: Full=Double-strand break repair protein MRE11A;
DE   AltName: Full=Meiotic recombination 11 homolog 1;
DE            Short=MRE11 homolog 1;
DE   AltName: Full=Meiotic recombination 11 homolog A;
DE            Short=MRE11 homolog A;
GN   Name=MRE11A; Synonyms=HNGS1, MRE11;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0004518; F:nuclease activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0000014; F:single-stranded DNA endodeoxyribonuclease activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; TAS:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; IMP:BHF-UCL.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IDA:BHF-UCL.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0000019; P:regulation of mitotic recombination; TAS:ProtInc.
DR   GO; GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; TAS:ProtInc.
//
ID   MREG_HUMAN              Reviewed;         214 AA.
AC   Q8N565; Q53R89; Q53TC1; Q5XKB6; Q9NWC9; Q9P1S1;
DE   RecName: Full=Melanoregulin;
DE   AltName: Full=Dilute suppressor protein homolog;
GN   Name=MREG; Synonyms=DSU; ORFNames=HDCGA21P;
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
//
ID   MRFL_HUMAN              Reviewed;         910 AA.
AC   Q96LU7;
DE   RecName: Full=Myelin regulatory factor-like protein;
GN   Name=MYRFL; Synonyms=C12orf15, C12orf28;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   MRF_HUMAN               Reviewed;        1151 AA.
AC   Q9Y2G1; O43582; Q9P1Q6;
DE   RecName: Full=Myelin regulatory factor;
DE            EC=3.4.-.-;
DE   AltName: Full=Myelin gene regulatory factor;
DE   Contains:
DE     RecName: Full=Myelin regulatory factor, N-terminal;
DE   Contains:
DE     RecName: Full=Myelin regulatory factor, C-terminal;
GN   Name=MYRF; Synonyms=C11orf9, KIAA0954, MRF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0032286; P:central nervous system myelin maintenance; ISS:UniProtKB.
DR   GO; GO:0022010; P:central nervous system myelination; ISS:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MRGBP_HUMAN             Reviewed;         204 AA.
AC   Q9NV56; A8C4L5;
DE   RecName: Full=MRG/MORF4L-binding protein;
DE   AltName: Full=MRG-binding protein;
DE   AltName: Full=Up-regulated in colon cancer 4;
DE            Short=Urcc4;
GN   Name=MRGBP; Synonyms=C20orf20;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MRGRD_HUMAN             Reviewed;         321 AA.
AC   Q8TDS7; Q8NGK7;
DE   RecName: Full=Mas-related G-protein coupled receptor member D;
DE   AltName: Full=Beta-alanine receptor;
DE   AltName: Full=G-protein coupled receptor TGR7;
GN   Name=MRGPRD; Synonyms=MRGD;
DR   GuidetoPHARMACOLOGY; 152; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MRGRE_HUMAN             Reviewed;         311 AA.
AC   Q86SM8; Q2M1V7;
DE   RecName: Full=Mas-related G-protein coupled receptor member E;
DE   AltName: Full=G-protein coupled receptor 167;
GN   Name=MRGPRE; Synonyms=GPR167, MRGE;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MRGRG_HUMAN             Reviewed;         289 AA.
AC   Q86SM5;
DE   RecName: Full=Mas-related G-protein coupled receptor member G;
DE   AltName: Full=G-protein coupled receptor 169;
GN   Name=MRGPRG; Synonyms=GPR169, MRGG;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MRGRF_HUMAN             Reviewed;         343 AA.
AC   Q96AM1; B3KV43; Q8NBK8;
DE   RecName: Full=Mas-related G-protein coupled receptor member F;
DE            Short=Mas-related gene F protein;
DE   AltName: Full=G-protein coupled receptor 140;
DE   AltName: Full=G-protein coupled receptor 168;
GN   Name=MRGPRF; Synonyms=GPR140, GPR168, MRGF; ORFNames=PSEC0142;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MRGX1_HUMAN             Reviewed;         322 AA.
AC   Q96LB2; Q4V9L2; Q8TDD8; Q8TDD9;
DE   RecName: Full=Mas-related G-protein coupled receptor member X1;
DE   AltName: Full=Sensory neuron-specific G-protein coupled receptor 3/4;
GN   Name=MRGPRX1; Synonyms=MRGX1, SNSR3, SNSR4;
DR   GuidetoPHARMACOLOGY; 156; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
//
ID   MRGX2_HUMAN             Reviewed;         330 AA.
AC   Q96LB1; B5B0C7; Q4QXW4; Q4QXW7; Q4QXX0; Q4QXX2; Q4QXX3; Q4QXX4;
AC   Q4QXX6; Q4QXX7;
DE   RecName: Full=Mas-related G-protein coupled receptor member X2;
GN   Name=MRGPRX2; Synonyms=MRGX2;
DR   GuidetoPHARMACOLOGY; 157; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0042923; F:neuropeptide binding; IPI:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0019233; P:sensory perception of pain; NAS:UniProtKB.
DR   GO; GO:0030431; P:sleep; NAS:UniProtKB.
//
ID   MRGX3_HUMAN             Reviewed;         322 AA.
AC   Q96LB0; B0M0L1; Q8TDE0; Q8TDE1;
DE   RecName: Full=Mas-related G-protein coupled receptor member X3;
DE   AltName: Full=Sensory neuron-specific G-protein coupled receptor 1/2;
GN   Name=MRGPRX3; Synonyms=MRGX3, SNSR1, SNSR2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MRGX4_HUMAN             Reviewed;         322 AA.
AC   Q96LA9; Q3KNU3; Q3KNU4; Q502W0; Q8TDD6; Q8TDD7;
DE   RecName: Full=Mas-related G-protein coupled receptor member X4;
DE   AltName: Full=Sensory neuron-specific G-protein coupled receptor 5/6;
GN   Name=MRGPRX4; Synonyms=MRGX4, SNSR5, SNSR6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   MRI_HUMAN               Reviewed;         157 AA.
AC   Q9BWK5; Q6NWZ4; Q6ZNR5;
DE   RecName: Full=Modulator of retrovirus infection homolog;
GN   Name=MRI; Synonyms=C7orf49;
//
ID   MRM1_HUMAN              Reviewed;         353 AA.
AC   Q6IN84; A8K8E2; Q96GK2; Q9H664;
DE   RecName: Full=rRNA methyltransferase 1, mitochondrial;
DE            EC=2.1.1.-;
DE   AltName: Full=Mitochondrial large ribosomal RNA ribose methylase;
DE   Flags: Precursor;
GN   Name=MRM1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   MRO2A_HUMAN             Reviewed;        1706 AA.
AC   A6NES4;
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 2A;
DE   AltName: Full=HEAT repeat-containing protein 7B1;
GN   Name=MROH2A; Synonyms=HEATR7B1;
//
ID   MRO2B_HUMAN             Reviewed;        1585 AA.
AC   Q7Z745; Q68DM1; Q7Z4U4; Q8N7X3;
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 2B;
DE   AltName: Full=HEAT repeat-containing protein 7B2;
GN   Name=MROH2B; Synonyms=HEATR7B2;
//
ID   MROH1_HUMAN             Reviewed;        1641 AA.
AC   Q8NDA8; C9JWM5; D3DWL5; Q0P612; Q569G6; Q6NVW4; Q8N230; Q8NAD1;
AC   Q8ND95; Q96JJ4;
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 1;
DE   AltName: Full=HEAT repeat-containing protein 7A;
GN   Name=MROH1; Synonyms=HEATR7A, KIAA1833;
//
ID   MROH5_HUMAN             Reviewed;        1318 AA.
AC   Q6ZUA9;
DE   RecName: Full=Maestro heat-like repeat family member 5;
GN   Name=MROH5;
//
ID   MROH6_HUMAN             Reviewed;         719 AA.
AC   A6NGR9; A8MWB1;
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 6;
GN   Name=MROH6; Synonyms=C8orf73;
//
ID   MROH7_HUMAN             Reviewed;        1323 AA.
AC   Q68CQ1; A0AUX8; Q5TA99; Q6ZP40; Q6ZRH6; Q8N311; Q8NA14;
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 7;
DE   AltName: Full=HEAT repeat-containing protein 8;
GN   Name=MROH7; Synonyms=C1orf175, HEATR8;
//
ID   MROH8_HUMAN             Reviewed;         483 AA.
AC   Q9H579; Q5JYQ6;
DE   RecName: Full=Protein MROH8;
DE   AltName: Full=Maestro heat-like repeat-containing protein family member 8;
GN   Name=MROH8; Synonyms=C20orf131, C20orf132;
//
ID   MROH9_HUMAN             Reviewed;         573 AA.
AC   Q5TGP6; A0PJM0; A0PJM2; F5GWX6; Q9H5D7;
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 9;
GN   Name=MROH9; Synonyms=C1orf129;
//
ID   MRP1_HUMAN              Reviewed;        1531 AA.
AC   P33527; A3RJX2; C9JPJ4; O14819; O43333; P78419; Q59GI9; Q9UQ97;
AC   Q9UQ99; Q9UQA0;
DE   RecName: Full=Multidrug resistance-associated protein 1;
DE   AltName: Full=ATP-binding cassette sub-family C member 1;
DE   AltName: Full=Leukotriene C(4) transporter;
DE            Short=LTC4 transporter;
GN   Name=ABCC1; Synonyms=MRP, MRP1;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0006691; P:leukotriene metabolic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MRP2_HUMAN              Reviewed;        1545 AA.
AC   Q92887; B2RMT8; Q14022; Q5T2B1; Q92500; Q92798; Q99663; Q9UMS2;
DE   RecName: Full=Canalicular multispecific organic anion transporter 1;
DE   AltName: Full=ATP-binding cassette sub-family C member 2;
DE   AltName: Full=Canalicular multidrug resistance protein;
DE   AltName: Full=Multidrug resistance-associated protein 2;
GN   Name=ABCC2; Synonyms=CMOAT, CMOAT1, CMRP, MRP2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030644; P:cellular chloride ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006855; P:drug transmembrane transport; IEA:Ensembl.
DR   GO; GO:0015732; P:prostaglandin transport; IEA:Ensembl.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0031427; P:response to methotrexate; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0070327; P:thyroid hormone transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MRP3_HUMAN              Reviewed;        1527 AA.
AC   O15438; B2RPA9; D3DTX9; O60265; O60922; O75621; O95078; O95289;
AC   O95290; Q86X85; Q9UN52;
DE   RecName: Full=Canalicular multispecific organic anion transporter 2;
DE   AltName: Full=ATP-binding cassette sub-family C member 3;
DE   AltName: Full=Multi-specific organic anion transporter D;
DE            Short=MOAT-D;
DE   AltName: Full=Multidrug resistance-associated protein 3;
GN   Name=ABCC3; Synonyms=CMOAT2, MLP2, MRP3;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MRP5_HUMAN              Reviewed;        1437 AA.
AC   O15440; B9EIQ2; O14517; Q29ZA9; Q29ZB1; Q86W30; Q9UN85; Q9UNP5;
AC   Q9UQC3;
DE   RecName: Full=Multidrug resistance-associated protein 5;
DE   AltName: Full=ATP-binding cassette sub-family C member 5;
DE   AltName: Full=Multi-specific organic anion transporter C;
DE            Short=MOAT-C;
DE   AltName: Full=SMRP;
DE   AltName: Full=pABC11;
GN   Name=ABCC5; Synonyms=MRP5;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030213; P:hyaluronan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0015711; P:organic anion transport; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   MRP4_HUMAN              Reviewed;        1325 AA.
AC   O15439; A9Z1Z7; Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2;
DE   RecName: Full=Multidrug resistance-associated protein 4;
DE   AltName: Full=ATP-binding cassette sub-family C member 4;
DE   AltName: Full=MRP/cMOAT-related ABC transporter;
DE   AltName: Full=Multi-specific organic anion transporter B;
DE            Short=MOAT-B;
GN   Name=ABCC4; Synonyms=MRP4;
DR   GO; GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; NAS:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MRP6_HUMAN              Reviewed;        1503 AA.
AC   O95255; P78420; Q8TCY8; Q9UMZ7;
DE   RecName: Full=Multidrug resistance-associated protein 6;
DE   AltName: Full=ATP-binding cassette sub-family C member 6;
DE   AltName: Full=Anthracycline resistance-associated protein;
DE   AltName: Full=Multi-specific organic anion transporter E;
DE            Short=MOAT-E;
GN   Name=ABCC6; Synonyms=ARA, MRP6;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   MRP7_HUMAN              Reviewed;        1492 AA.
AC   Q5T3U5; Q8NHX7; Q9H7N2; Q9NXY3; Q9UF48;
DE   RecName: Full=Multidrug resistance-associated protein 7;
DE   AltName: Full=ATP-binding cassette sub-family C member 10;
GN   Name=ABCC10; Synonyms=MRP7, SIMRP7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MRP9_HUMAN              Reviewed;        1359 AA.
AC   Q96J65; Q49AL2; Q8TAF0; Q8TEY2;
DE   RecName: Full=Multidrug resistance-associated protein 9;
DE   AltName: Full=ATP-binding cassette sub-family C member 12;
GN   Name=ABCC12; Synonyms=MRP9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
//
ID   MRP_HUMAN               Reviewed;         195 AA.
AC   P49006; D3DPQ0; Q5TEE6; Q6NXS5;
DE   RecName: Full=MARCKS-related protein;
DE   AltName: Full=MARCKS-like protein 1;
DE   AltName: Full=Macrophage myristoylated alanine-rich C kinase substrate;
DE            Short=Mac-MARCKS;
DE            Short=MacMARCKS;
GN   Name=MARCKSL1; Synonyms=MLP, MRP;
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   MRRP1_HUMAN             Reviewed;         403 AA.
AC   Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596;
DE   RecName: Full=Mitochondrial ribonuclease P protein 1;
DE            Short=Mitochondrial RNase P protein 1;
DE            EC=2.1.1.-;
DE   AltName: Full=HBV pre-S2 trans-regulated protein 2;
DE   AltName: Full=RNA (guanine-9-)-methyltransferase domain-containing protein 1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-49;
DE   AltName: Full=tRNA methyltransferase 10 homolog C;
DE   Flags: Precursor;
GN   Name=TRMT10C; Synonyms=MRPP1, RG9MTD1;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000964; P:mitochondrial RNA 5'-end processing; IMP:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   MRRP3_HUMAN             Reviewed;         583 AA.
AC   O15091; B4DXD9; B4E0S8; B4E211; C4AM93; D3DS99; D3DSA1; Q86SZ4;
AC   Q86YB5; Q8N5L5;
DE   RecName: Full=Mitochondrial ribonuclease P protein 3;
DE            Short=Mitochondrial RNase P protein 3;
DE   Flags: Precursor;
GN   Name=KIAA0391; Synonyms=MRPP3;
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   MRS2_HUMAN              Reviewed;         443 AA.
AC   Q9HD23; A8K4U3; B3KNN2; Q5T3Y1; Q6NTG4; Q96KF8; Q9BVP1;
DE   RecName: Full=Magnesium transporter MRS2 homolog, mitochondrial;
DE   AltName: Full=MRS2-like protein;
DE   Flags: Precursor;
GN   Name=MRS2; Synonyms=HPT, MRS2L;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
//
ID   MRT4_HUMAN              Reviewed;         239 AA.
AC   Q9UKD2; B3KNB3; Q5TG55; Q96SS6; Q9BPV9;
DE   RecName: Full=mRNA turnover protein 4 homolog;
GN   Name=MRTO4; Synonyms=C1orf33, MRT4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   MRVI1_HUMAN             Reviewed;         885 AA.
AC   Q9Y6F6; B7Z3T4; B7Z6I2; B7Z9A3; E9PQY6; F5H6A1; J3KQZ7; Q17S00;
AC   Q9UNY1;
DE   RecName: Full=Protein MRVI1;
DE   AltName: Full=Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate;
DE   AltName: Full=JAW1-related protein MRVI1;
GN   Name=MRVI1; Synonyms=IRAG, JAW1L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
//
ID   MS18B_HUMAN             Reviewed;         229 AA.
AC   O43482; Q96BX7;
DE   RecName: Full=Protein Mis18-beta;
DE   AltName: Full=Cancer/testis antigen 86;
DE            Short=CT86;
DE   AltName: Full=Opa-interacting protein 5;
DE            Short=OIP-5;
GN   Name=OIP5; Synonyms=MIS18B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007154; P:cell communication; NAS:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
//
ID   MS18A_HUMAN             Reviewed;         233 AA.
AC   Q9NYP9; B2R562; Q542Z0;
DE   RecName: Full=Protein Mis18-alpha;
DE   AltName: Full=FAPP1-associated protein 1;
GN   Name=MIS18A; Synonyms=C21orf45, C21orf46, FASP1;
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007059; P:chromosome segregation; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0044030; P:regulation of DNA methylation; IEA:Ensembl.
//
ID   MS3L1_HUMAN             Reviewed;         521 AA.
AC   Q8N5Y2; A6NCU2; A6NHW8; A8K165; B4DUV8; Q9UG70; Q9Y5Z8;
DE   RecName: Full=Male-specific lethal 3 homolog;
DE   AltName: Full=Male-specific lethal-3 homolog 1;
DE   AltName: Full=Male-specific lethal-3 protein-like 1;
DE            Short=MSL3-like 1;
GN   Name=MSL3; Synonyms=MSL3L1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MS3L2_HUMAN             Reviewed;         447 AA.
AC   P0C860;
DE   RecName: Full=Putative male-specific lethal-3 protein-like 2;
DE            Short=MSL3-like 2;
DE   AltName: Full=Male-specific lethal-3 homolog 2;
DE   AltName: Full=Male-specific lethal-3 homolog pseudogene 1;
GN   Name=MSL3P1; Synonyms=MSL3L2;
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MS4A3_HUMAN             Reviewed;         214 AA.
AC   Q96HJ5; A8MTP8; Q8NHW2;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 3;
DE   AltName: Full=CD20 antigen-like protein;
DE   AltName: Full=Hematopoietic-specific transmembrane protein 4;
DE            Short=HTm4;
GN   Name=MS4A3; Synonyms=CD20L, HTM4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   MS4A5_HUMAN             Reviewed;         200 AA.
AC   Q9H3V2; Q9BZH1;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 5;
DE   AltName: Full=CD20 antigen-like 2;
DE   AltName: Full=Testis-expressed transmembrane protein 4;
GN   Name=MS4A5; Synonyms=CD20L2, TETM4;
//
ID   MS4A7_HUMAN             Reviewed;         240 AA.
AC   Q9GZW8; A6NP53; Q6IAG8;
DE   RecName: Full=Membrane-spanning 4-domains subfamily A member 7;
DE   AltName: Full=CD20 antigen-like 4;
DE   AltName: Full=CD20/FC-epsilon-RI-beta family member 4;
DE   AltName: Full=Four-span transmembrane protein 2;
GN   Name=MS4A7; Synonyms=4SPAN2, CD20L4, CFFM4;
//
ID   MSD1_HUMAN              Reviewed;         278 AA.
AC   Q6ZTZ1; C9J6V0;
DE   RecName: Full=Myb/SANT-like DNA-binding domain-containing protein 1;
GN   Name=MSANTD1; Synonyms=C4orf44;
//
ID   MSD2_HUMAN              Reviewed;         559 AA.
AC   Q6P1R3; B3KRY6; Q9H042; Q9H5K8;
DE   RecName: Full=Myb/SANT-like DNA-binding domain-containing protein 2;
GN   Name=MSANTD2; Synonyms=C11orf61;
//
ID   MSD3_HUMAN              Reviewed;         275 AA.
AC   Q96H12; B2RC35; Q5T726; Q5T727; Q5T728;
DE   RecName: Full=Myb/SANT-like DNA-binding domain-containing protein 3;
GN   Name=MSANTD3; Synonyms=C9orf30; ORFNames=L8;
//
ID   MSD4_HUMAN              Reviewed;         345 AA.
AC   Q8NCY6; Q96JK1; Q96JZ3; Q9H2N4;
DE   RecName: Full=Myb/SANT-like DNA-binding domain-containing protein 4;
DE   AltName: Full=Myb/SANT-like DNA-binding domain containing 4 with coiled-coils;
GN   Name=MSANTD4; Synonyms=KIAA1826; ORFNames=DC25;
//
ID   MSGN1_HUMAN             Reviewed;         193 AA.
AC   A6NI15;
DE   RecName: Full=Mesogenin-1;
DE   AltName: Full=Paraxial mesoderm-specific mesogenin1;
DE   AltName: Full=pMesogenin1;
DE            Short=pMsgn1;
GN   Name=MSGN1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007379; P:segment specification; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MSH2_HUMAN              Reviewed;         934 AA.
AC   P43246; B4E2Z2; O75488;
DE   RecName: Full=DNA mismatch repair protein Msh2;
DE            Short=hMSH2;
DE   AltName: Full=MutS protein homolog 2;
GN   Name=MSH2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019237; F:centromeric DNA binding; IEA:Ensembl.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.
DR   GO; GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0032137; F:guanine/thymine mispair binding; IMP:MGI.
DR   GO; GO:0000404; F:heteroduplex DNA loop binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0030183; P:B cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0019724; P:B cell mediated immunity; ISS:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; IDA:BHF-UCL.
DR   GO; GO:0006302; P:double-strand break repair; IBA:RefGenome.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IBA:RefGenome.
DR   GO; GO:0045190; P:isotype switching; ISS:BHF-UCL.
DR   GO; GO:0043570; P:maintenance of DNA repeat elements; IMP:HGNC.
DR   GO; GO:0008584; P:male gonad development; ISS:BHF-UCL.
DR   GO; GO:0006311; P:meiotic gene conversion; IBA:RefGenome.
DR   GO; GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.
DR   GO; GO:0006298; P:mismatch repair; IDA:UniProtKB.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0006119; P:oxidative phosphorylation; IEA:Ensembl.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.
DR   GO; GO:0006301; P:postreplication repair; IDA:UniProtKB.
DR   GO; GO:0010224; P:response to UV-B; ISS:BHF-UCL.
DR   GO; GO:0010165; P:response to X-ray; ISS:BHF-UCL.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
DR   GO; GO:0016447; P:somatic recombination of immunoglobulin gene segments; ISS:BHF-UCL.
//
ID   MSH3_HUMAN              Reviewed;        1137 AA.
AC   P20585; A1L480; A1L482; A6NMM6; Q6PJT5; Q86UQ6; Q92867;
DE   RecName: Full=DNA mismatch repair protein Msh3;
DE            Short=hMSH3;
DE   AltName: Full=Divergent upstream protein;
DE            Short=DUP;
DE   AltName: Full=Mismatch repair protein 1;
DE            Short=MRP1;
GN   Name=MSH3; Synonyms=DUC1, DUG;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0019237; F:centromeric DNA binding; IEA:Ensembl.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.
DR   GO; GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0000404; F:heteroduplex DNA loop binding; IBA:RefGenome.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006281; P:DNA repair; IDA:BHF-UCL.
DR   GO; GO:0043570; P:maintenance of DNA repeat elements; IMP:HGNC.
DR   GO; GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IDA:BHF-UCL.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0016447; P:somatic recombination of immunoglobulin gene segments; IBA:RefGenome.
//
ID   MSH4_HUMAN              Reviewed;         936 AA.
AC   O15457; Q5T4U6; Q8NEB3; Q9UNP8;
DE   RecName: Full=MutS protein homolog 4;
DE            Short=hMSH4;
GN   Name=MSH4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.
DR   GO; GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0051026; P:chiasma assembly; IBA:RefGenome.
DR   GO; GO:0007292; P:female gamete generation; IEA:Ensembl.
DR   GO; GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   MSH5_HUMAN              Reviewed;         834 AA.
AC   O43196; B0V033; B0V034; O60586; Q5BLU9; Q5SSR1; Q8IW44; Q9BQC7;
DE   RecName: Full=MutS protein homolog 5;
DE            Short=hMSH5;
GN   Name=MSH5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.
DR   GO; GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0051026; P:chiasma assembly; IBA:RefGenome.
DR   GO; GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0007136; P:meiotic prophase II; TAS:ProtInc.
DR   GO; GO:0006298; P:mismatch repair; TAS:ProtInc.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
//
ID   MSH6_HUMAN              Reviewed;        1360 AA.
AC   P52701; B4DF41; O43706; O43917; Q8TCX4; Q9BTB5;
DE   RecName: Full=DNA mismatch repair protein Msh6;
DE            Short=hMSH6;
DE   AltName: Full=G/T mismatch-binding protein;
DE            Short=GTBP;
DE            Short=GTMBP;
DE   AltName: Full=MutS-alpha 160 kDa subunit;
DE            Short=p160;
GN   Name=MSH6; Synonyms=GTBP;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.
DR   GO; GO:0032137; F:guanine/thymine mispair binding; IEA:Ensembl.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0008340; P:determination of adult lifespan; ISS:BHF-UCL.
DR   GO; GO:0006281; P:DNA repair; IDA:BHF-UCL.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; ISS:BHF-UCL.
DR   GO; GO:0045190; P:isotype switching; ISS:BHF-UCL.
DR   GO; GO:0000710; P:meiotic mismatch repair; ISS:BHF-UCL.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IDA:BHF-UCL.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0009411; P:response to UV; ISS:BHF-UCL.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; ISS:BHF-UCL.
DR   GO; GO:0016447; P:somatic recombination of immunoglobulin gene segments; ISS:BHF-UCL.
//
ID   MSHR_HUMAN              Reviewed;         317 AA.
AC   Q01726; Q66K38; Q6UR93; Q8WWX6; Q8WWX7; Q96I33; Q96RU4; Q9UBF7;
AC   Q9UN58; Q9UN59; Q9UN60; Q9UN61; Q9UN62;
DE   RecName: Full=Melanocyte-stimulating hormone receptor;
DE            Short=MSH-R;
DE   AltName: Full=Melanocortin receptor 1;
DE            Short=MC1-R;
GN   Name=MC1R; Synonyms=MSHR;
DR   GuidetoPHARMACOLOGY; 282; -.
DR   GO; GO:0008528; F:G-protein coupled peptide receptor activity; TAS:BHF-UCL.
DR   GO; GO:0004977; F:melanocortin receptor activity; TAS:ProtInc.
DR   GO; GO:0004980; F:melanocyte-stimulating hormone receptor activity; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:BHF-UCL.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0043473; P:pigmentation; TAS:BHF-UCL.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; ISS:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:BHF-UCL.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0009650; P:UV protection; TAS:ProtInc.
DR   GO; GO:0070914; P:UV-damage excision repair; IDA:BHF-UCL.
//
ID   MSI1H_HUMAN             Reviewed;         362 AA.
AC   O43347; Q96PU0; Q96PU1; Q96PU2; Q96PU3;
DE   RecName: Full=RNA-binding protein Musashi homolog 1;
DE            Short=Musashi-1;
GN   Name=MSI1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
//
ID   MSI2H_HUMAN             Reviewed;         328 AA.
AC   Q96DH6; Q7Z6M7; Q8N9T4;
DE   RecName: Full=RNA-binding protein Musashi homolog 2;
DE            Short=Musashi-2;
GN   Name=MSI2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IEA:Ensembl.
DR   GO; GO:0048864; P:stem cell development; IEA:Ensembl.
//
ID   MSL1_HUMAN              Reviewed;         614 AA.
AC   Q68DK7; Q0VF46; Q69Z03;
DE   RecName: Full=Male-specific lethal 1 homolog;
DE            Short=MSL-1;
DE   AltName: Full=Male-specific lethal 1-like 1;
DE            Short=MSL1-like 1;
DE   AltName: Full=Male-specific lethal-1 homolog 1;
GN   Name=MSL1; Synonyms=MSL1L1;
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
//
ID   MSL2_HUMAN              Reviewed;         577 AA.
AC   Q9HCI7; B4DYL4; G5E9I1; Q0D2P1; Q8NDB4; Q9NVS4;
DE   RecName: Full=E3 ubiquitin-protein ligase MSL2;
DE            EC=6.3.2.-;
DE   AltName: Full=Male-specific lethal 2-like 1;
DE            Short=MSL2-like 1;
DE   AltName: Full=Male-specific lethal-2 homolog;
DE            Short=MSL-2;
DE   AltName: Full=Male-specific lethal-2 homolog 1;
DE   AltName: Full=RING finger protein 184;
GN   Name=MSL2; Synonyms=KIAA1585, MSL2L1, RNF184;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
//
ID   MSLNL_HUMAN             Reviewed;         702 AA.
AC   Q96KJ4;
DE   RecName: Full=Mesothelin-like protein;
DE   AltName: Full=Pre-pro-megakaryocyte-potentiating-factor-like;
DE   Flags: Precursor;
GN   Name=MSLNL; Synonyms=C16orf37, MPFL;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   MSLN_HUMAN              Reviewed;         630 AA.
AC   Q13421; D3DU65; Q14859; Q4VQD5; Q96GR6; Q96KJ5; Q9BR17; Q9BTR2;
AC   Q9UCB2; Q9UK57;
DE   RecName: Full=Mesothelin;
DE   AltName: Full=CAK1 antigen;
DE   AltName: Full=Pre-pro-megakaryocyte-potentiating factor;
DE   Contains:
DE     RecName: Full=Megakaryocyte-potentiating factor;
DE              Short=MPF;
DE   Contains:
DE     RecName: Full=Mesothelin, cleaved form;
DE   Flags: Precursor;
GN   Name=MSLN; Synonyms=MPF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
//
ID   MSMB_HUMAN              Reviewed;         114 AA.
AC   P08118; B1API6; P11999; Q13125; Q6IAY9; Q9UC59;
DE   RecName: Full=Beta-microseminoprotein;
DE   AltName: Full=Immunoglobulin-binding factor;
DE            Short=IGBF;
DE   AltName: Full=PN44;
DE   AltName: Full=Prostate secreted seminal plasma protein;
DE   AltName: Full=Prostate secretory protein of 94 amino acids;
DE            Short=PSP-94;
DE            Short=PSP94;
DE   AltName: Full=Seminal plasma beta-inhibin;
DE   Flags: Precursor;
GN   Name=MSMB; Synonyms=PRSP;
//
ID   MSMO1_HUMAN             Reviewed;         293 AA.
AC   Q15800; A8K8Q3; A8MYF6; D3DP32; Q32Q24;
DE   RecName: Full=Methylsterol monooxygenase 1;
DE            EC=1.14.13.72;
DE   AltName: Full=C-4 methylsterol oxidase;
GN   Name=MSMO1; Synonyms=DESP4, ERG25, SC4MOL;
DR   GO; GO:0000254; F:C-4 methylsterol oxidase activity; TAS:ProtInc.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
//
ID   MSMP_HUMAN              Reviewed;         139 AA.
AC   Q1L6U9;
DE   RecName: Full=Prostate-associated microseminoprotein;
DE   AltName: Full=PC3-secreted microprotein;
DE   Flags: Precursor;
GN   Name=MSMP; Synonyms=PSMP;
//
ID   MSPD1_HUMAN             Reviewed;         213 AA.
AC   Q9UJG1; B2RE62; D3DTG5; Q5H9C5; Q5H9C7;
DE   RecName: Full=Motile sperm domain-containing protein 1;
GN   Name=MOSPD1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   MSPD2_HUMAN             Reviewed;         518 AA.
AC   Q8NHP6; Q8N3H2; Q8NA83;
DE   RecName: Full=Motile sperm domain-containing protein 2;
GN   Name=MOSPD2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   MSPD3_HUMAN             Reviewed;         235 AA.
AC   O75425; A4D2D1; A6NG17; C9JE89; D6W5W1; O75423; O75424;
DE   RecName: Full=Motile sperm domain-containing protein 3;
GN   Name=MOSPD3;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
//
ID   MSRA_HUMAN              Reviewed;         235 AA.
AC   Q9UJ68; E9PAS8; Q52TC4; Q549N4; Q66MI7;
DE   RecName: Full=Mitochondrial peptide methionine sulfoxide reductase;
DE            EC=1.8.4.11;
DE   AltName: Full=Peptide-methionine (S)-S-oxide reductase;
DE            Short=Peptide Met(O) reductase;
DE   AltName: Full=Protein-methionine-S-oxide reductase;
DE            Short=PMSR;
DE   Flags: Precursor;
GN   Name=MSRA;
DR   GO; GO:0008113; F:peptide-methionine (S)-S-oxide reductase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006555; P:methionine metabolic process; TAS:ProtInc.
DR   GO; GO:0030091; P:protein repair; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
//
ID   MSRB1_HUMAN             Reviewed;         116 AA.
AC   Q9NZV6; Q96RX6; Q9BTV2; Q9P0B1;
DE   RecName: Full=Methionine-R-sulfoxide reductase B1;
DE            Short=MsrB1;
DE            EC=1.8.4.-;
DE   AltName: Full=Selenoprotein X;
DE            Short=SelX;
GN   Name=MSRB1; Synonyms=SEPX1; ORFNames=HSPC270;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0070191; F:methionine-R-sulfoxide reductase activity; IEA:Ensembl.
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:HGNC.
DR   GO; GO:0030041; P:actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; ISS:UniProtKB.
DR   GO; GO:0030091; P:protein repair; ISS:HGNC.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   MSRB2_HUMAN             Reviewed;         182 AA.
AC   Q9Y3D2; Q17R44; Q4G1C7; Q9Y5W6;
DE   RecName: Full=Methionine-R-sulfoxide reductase B2, mitochondrial;
DE            Short=MsrB2;
DE            EC=1.8.4.-;
DE   Flags: Precursor;
GN   Name=MSRB2; Synonyms=CBS-1, MSRB; ORFNames=CGI-131;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; ISS:HGNC.
DR   GO; GO:0030041; P:actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0030091; P:protein repair; ISS:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   MSRB3_HUMAN             Reviewed;         192 AA.
AC   Q8IXL7; B4DR19; B7ZAQ0; Q6UXS2;
DE   RecName: Full=Methionine-R-sulfoxide reductase B3;
DE            Short=MsrB3;
DE            EC=1.8.4.-;
DE   Flags: Precursor;
GN   Name=MSRB3; ORFNames=UNQ1965/PRO4487;
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase activity; IDA:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IDA:HGNC.
DR   GO; GO:0030091; P:protein repair; IDA:HGNC.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
//
ID   MSRE_HUMAN              Reviewed;         451 AA.
AC   P21757; D3DSP3; O60505; P21759; Q45F10;
DE   RecName: Full=Macrophage scavenger receptor types I and II;
DE   AltName: Full=Macrophage acetylated LDL receptor I and II;
DE   AltName: Full=Scavenger receptor class A member 1;
DE   AltName: CD_antigen=CD204;
GN   Name=MSR1; Synonyms=SCARA1;
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005044; F:scavenger receptor activity; TAS:ProtInc.
DR   GO; GO:0030301; P:cholesterol transport; ISS:BHF-UCL.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0034381; P:plasma lipoprotein particle clearance; ISS:BHF-UCL.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; ISS:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
//
ID   MSS4_HUMAN              Reviewed;         123 AA.
AC   P47224; B2R4P4; Q92992;
DE   RecName: Full=Guanine nucleotide exchange factor MSS4;
DE   AltName: Full=Rab-interacting factor;
GN   Name=RABIF; Synonyms=MSS4, RASGRF3;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043087; P:regulation of GTPase activity; NAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   MSS51_HUMAN             Reviewed;         460 AA.
AC   Q4VC12; A6NGH6; Q2VP95; Q5F2H5; Q7Z3M9; Q8N8G0;
DE   RecName: Full=Putative protein MSS51 homolog, mitochondrial;
DE   AltName: Full=Zinc finger MYND domain-containing protein 17;
GN   Name=MSS51; Synonyms=ZMYND17;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035176; P:social behavior; IEP:UniProtKB.
//
ID   MST1L_HUMAN             Reviewed;         715 AA.
AC   Q2TV78; B7WPB1; Q13209;
DE   RecName: Full=Putative macrophage stimulating 1-like protein;
DE   AltName: Full=Brain rescue factor 1;
DE            Short=BRF-1;
DE   AltName: Full=Hepatocyte growth factor-like protein homolog;
DE   Flags: Precursor;
GN   Name=MST1L; Synonyms=D1F15S1A, MST1P9, MSTP9;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   MST4_HUMAN              Reviewed;         416 AA.
AC   Q9P289; B2RAU2; Q3ZB77; Q8NC04; Q9BXC3; Q9BXC4;
DE   RecName: Full=Serine/threonine-protein kinase MST4;
DE            EC=2.7.11.1;
DE   AltName: Full=Mammalian STE20-like protein kinase 4;
DE            Short=MST-4;
DE   AltName: Full=Mst3 and SOK1-related kinase;
DE   AltName: Full=STE20-like kinase MST4;
DE   AltName: Full=Serine/threonine-protein kinase MASK;
GN   Name=MST4; Synonyms=MASK;
DR   GuidetoPHARMACOLOGY; 2287; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; IBA:RefGenome.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   MSTN1_HUMAN             Reviewed;          82 AA.
AC   Q8IVN3;
DE   RecName: Full=Musculoskeletal embryonic nuclear protein 1;
GN   Name=MUSTN1;
//
ID   MSTO1_HUMAN             Reviewed;         570 AA.
AC   Q9BUK6; Q53GR8; Q5CZ69; Q5T717; Q68CT6; Q7LBZ8; Q7Z3M7; Q7Z558;
AC   Q8TE05; Q9NQX2; Q9NVU4;
DE   RecName: Full=Protein misato homolog 1;
GN   Name=MSTO1; ORFNames=LST005, SLTP005;
DR   GO; GO:0048311; P:mitochondrion distribution; IMP:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
//
ID   MSTRO_HUMAN             Reviewed;         248 AA.
AC   Q9BYG7; B7Z2I5; B7Z3B2; E9PAT5; E9PBI3; K7EKJ8; Q8N6K5;
DE   RecName: Full=Protein maestro;
DE   AltName: Full=Male-specific transcription in the developing reproductive organs;
DE   AltName: Full=Protein B29;
GN   Name=MRO; Synonyms=B29, C18orf3;
//
ID   MSX1_HUMAN              Reviewed;         303 AA.
AC   P28360; A0SZU5; A8K3M1; Q96NY4;
DE   RecName: Full=Homeobox protein MSX-1;
DE   AltName: Full=Homeobox protein Hox-7;
DE   AltName: Full=Msh homeobox 1-like protein;
GN   Name=MSX1; Synonyms=HOX7;
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0090427; P:activation of meiosis; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0061312; P:BMP signaling pathway involved in heart development; IEA:Ensembl.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0071316; P:cellular response to nicotine; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035880; P:embryonic nail plate morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0061180; P:mammary gland epithelium development; IEA:Ensembl.
DR   GO; GO:0010463; P:mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051154; P:negative regulation of striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:BHF-UCL.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IC:BHF-UCL.
DR   GO; GO:1902255; P:positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:2001055; P:positive regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0042481; P:regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
//
ID   MSX2_HUMAN              Reviewed;         267 AA.
AC   P35548; D3DQN1; Q53XM4; Q9UD60;
DE   RecName: Full=Homeobox protein MSX-2;
DE   AltName: Full=Homeobox protein Hox-8;
GN   Name=MSX2; Synonyms=HOX8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; ISS:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0090427; P:activation of meiosis; IEA:Ensembl.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0061312; P:BMP signaling pathway involved in heart development; IEA:Ensembl.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0060363; P:cranial suture morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035880; P:embryonic nail plate morphogenesis; IEA:Ensembl.
DR   GO; GO:0070166; P:enamel mineralization; IEA:Ensembl.
DR   GO; GO:0003416; P:endochondral bone growth; IEA:Ensembl.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; IEA:Ensembl.
DR   GO; GO:0060364; P:frontal suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032792; P:negative regulation of CREB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0051795; P:positive regulation of catagen; IEA:Ensembl.
DR   GO; GO:2001055; P:positive regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IEA:Ensembl.
//
ID   MT1A_HUMAN              Reviewed;          61 AA.
AC   P04731; Q86YX5;
DE   RecName: Full=Metallothionein-1A;
DE            Short=MT-1A;
DE   AltName: Full=Metallothionein-IA;
DE            Short=MT-IA;
GN   Name=MT1A; Synonyms=MT1S;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1B_HUMAN              Reviewed;          61 AA.
AC   P07438; Q86YX0;
DE   RecName: Full=Metallothionein-1B;
DE            Short=MT-1B;
DE   AltName: Full=Metallothionein-IB;
DE            Short=MT-IB;
GN   Name=MT1B; Synonyms=MT1Q;
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1DP_HUMAN             Reviewed;          49 AA.
AC   A1L3X4; Q86YX1;
DE   RecName: Full=Putative metallothionein MT1DP;
GN   Name=MT1DP; Synonyms=MTM;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   MT1E_HUMAN              Reviewed;          61 AA.
AC   P04732; A2RRF7; Q86YX4; Q8TD51;
DE   RecName: Full=Metallothionein-1E;
DE            Short=MT-1E;
DE   AltName: Full=Metallothionein-IE;
DE            Short=MT-IE;
GN   Name=MT1E;
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1F_HUMAN              Reviewed;          61 AA.
AC   P04733; Q9UI97;
DE   RecName: Full=Metallothionein-1F;
DE            Short=MT-1F;
DE   AltName: Full=Metallothionein-IF;
DE            Short=MT-IF;
GN   Name=MT1F; ORFNames=PRO0376;
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; ISS:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1G_HUMAN              Reviewed;          62 AA.
AC   P13640; P80296;
DE   RecName: Full=Metallothionein-1G;
DE            Short=MT-1G;
DE   AltName: Full=Metallothionein-1K;
DE            Short=MT-1K;
DE   AltName: Full=Metallothionein-IG;
DE            Short=MT-IG;
GN   Name=MT1G; Synonyms=MT1K, MT1M;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEP:UniProtKB.
DR   GO; GO:0071280; P:cellular response to copper ion; IEP:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IDA:UniProtKB.
DR   GO; GO:0042117; P:monocyte activation; NAS:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; IDA:UniProtKB.
//
ID   MT1H_HUMAN              Reviewed;          61 AA.
AC   P80294; B2RUY6;
DE   RecName: Full=Metallothionein-1H;
DE            Short=MT-1H;
DE   AltName: Full=Metallothionein-0;
DE            Short=MT-0;
DE   AltName: Full=Metallothionein-IH;
DE            Short=MT-IH;
GN   Name=MT1H;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1L_HUMAN              Reviewed;          61 AA.
AC   Q93083;
DE   RecName: Full=Metallothionein-1L;
DE            Short=MT-1L;
DE   AltName: Full=Metallothionein-IL;
DE            Short=MT-IL;
GN   Name=MT1L;
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1M_HUMAN              Reviewed;          61 AA.
AC   Q8N339; Q8TDN3;
DE   RecName: Full=Metallothionein-1M;
DE            Short=MT-1M;
DE   AltName: Full=Metallothionein-IM;
DE            Short=MT-IM;
GN   Name=MT1M; Synonyms=MT1K;
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; ISS:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT1X_HUMAN              Reviewed;          61 AA.
AC   P80297; A8MUC7;
DE   RecName: Full=Metallothionein-1X;
DE            Short=MT-1X;
DE   AltName: Full=Metallothionein-IX;
DE            Short=MT-IX;
GN   Name=MT1X;
DR   GO; GO:0046872; F:metal ion binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEP:UniProtKB.
DR   GO; GO:0036018; P:cellular response to erythropoietin; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
DR   GO; GO:0010038; P:response to metal ion; TAS:ProtInc.
//
ID   MT21A_HUMAN             Reviewed;         218 AA.
AC   Q8WXB1; Q53RV0; Q8N1Z9; Q96GH6;
DE   RecName: Full=Protein N-lysine methyltransferase METTL21A;
DE            EC=2.1.1.-;
DE   AltName: Full=HSPA lysine methyltransferase;
DE   AltName: Full=HSPA-KMT;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 557b;
DE   AltName: Full=Methyltransferase-like protein 21A;
GN   Name=METTL21A; Synonyms=FAM119A, HCA557B;
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0018022; P:peptidyl-lysine methylation; IDA:BHF-UCL.
DR   GO; GO:0006479; P:protein methylation; IDA:UniProtKB.
//
ID   MT21B_HUMAN             Reviewed;         226 AA.
AC   Q96AZ1; Q9H749; Q9Y3W2;
DE   RecName: Full=Protein-lysine methyltransferase METTL21B;
DE            EC=2.1.1.-;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 557a;
DE   AltName: Full=Methyltransferase-like protein 21B;
GN   Name=METTL21B; Synonyms=FAM119B, HCA557A;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MT21C_HUMAN             Reviewed;         264 AA.
AC   Q5VZV1;
DE   RecName: Full=Protein-lysine methyltransferase METTL21C;
DE            EC=2.1.1.-;
DE   AltName: Full=Methyltransferase-like protein 21C;
GN   Name=METTL21C; Synonyms=C13orf39;
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0018022; P:peptidyl-lysine methylation; IDA:GOC.
DR   GO; GO:0006479; P:protein methylation; IDA:UniProtKB.
//
ID   MT21D_HUMAN             Reviewed;         229 AA.
AC   Q9H867; B7ZLA3; B7ZLA4; Q2M2X3; Q86T12;
DE   RecName: Full=Protein-lysine methyltransferase METTL21D;
DE            EC=2.1.1.-;
DE   AltName: Full=Methyltransferase-like protein 21D;
DE   AltName: Full=VCP lysine methyltransferase;
DE            Short=VCP-KMT;
DE   AltName: Full=Valosin-containing protein lysine methyltransferase;
GN   Name=VCPKMT; Synonyms=C14orf138, METTL21D;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0018023; P:peptidyl-lysine trimethylation; IDA:UniProtKB.
//
ID   MT21E_HUMAN             Reviewed;         271 AA.
AC   A6NDL7;
DE   RecName: Full=Putative methyltransferase-like protein 21E pseudogene;
DE            EC=2.1.1.-;
GN   Name=METTL21EP; Synonyms=METTL21CP1;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   MT2_HUMAN               Reviewed;          61 AA.
AC   P02795; Q14823; Q2HXR9; Q53XT9;
DE   RecName: Full=Metallothionein-2;
DE            Short=MT-2;
DE   AltName: Full=Metallothionein-2A;
DE   AltName: Full=Metallothionein-II;
DE            Short=MT-II;
GN   Name=MT2A; Synonyms=CES1, MT2;
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; TAS:ProtInc.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0036018; P:cellular response to erythropoietin; IEP:UniProtKB.
DR   GO; GO:0036016; P:cellular response to interleukin-3; IEP:UniProtKB.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEP:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045926; P:negative regulation of growth; ISS:UniProtKB.
//
ID   MT3_HUMAN               Reviewed;          68 AA.
AC   P25713; Q2V574;
DE   RecName: Full=Metallothionein-3;
DE            Short=MT-3;
DE   AltName: Full=GIFB;
DE            Short=GIF;
DE   AltName: Full=Growth inhibitory factor;
DE   AltName: Full=Metallothionein-III;
DE            Short=MT-III;
GN   Name=MT3;
DR   GO; GO:0016209; F:antioxidant activity; NAS:UniProtKB.
DR   GO; GO:0046870; F:cadmium ion binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:UniProtKB.
DR   GO; GO:0014002; P:astrocyte development; ISS:UniProtKB.
DR   GO; GO:0055073; P:cadmium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0044242; P:cellular lipid catabolic process; ISS:UniProtKB.
DR   GO; GO:0006875; P:cellular metal ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0071732; P:cellular response to nitric oxide; IDA:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEP:UniProtKB.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0006707; P:cholesterol catabolic process; ISS:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; ISS:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0016570; P:histone modification; IMP:UniProtKB.
DR   GO; GO:0033210; P:leptin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0030517; P:negative regulation of axon extension; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:2000117; P:negative regulation of cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060547; P:negative regulation of necrotic cell death; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; ISS:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0097214; P:positive regulation of lysosomal membrane permeability; ISS:UniProtKB.
DR   GO; GO:0010940; P:positive regulation of necrotic cell death; IDA:UniProtKB.
DR   GO; GO:2000376; P:positive regulation of oxygen metabolic process; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0036091; P:positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0060049; P:regulation of protein glycosylation; ISS:UniProtKB.
DR   GO; GO:0032095; P:regulation of response to food; ISS:UniProtKB.
DR   GO; GO:0019430; P:removal of superoxide radicals; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0055069; P:zinc ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006829; P:zinc ion transport; ISS:UniProtKB.
//
ID   MT4_HUMAN               Reviewed;          62 AA.
AC   P47944; Q14DA1;
DE   RecName: Full=Metallothionein-4;
DE            Short=MT-4;
DE   AltName: Full=Metallothionein-IV;
DE            Short=MT-IV;
GN   Name=MT4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006875; P:cellular metal ion homeostasis; IEA:Ensembl.
//
ID   MTA1_HUMAN              Reviewed;         715 AA.
AC   Q13330; A5PLK4; Q86SW2; Q8NFI8; Q96GI8;
DE   RecName: Full=Metastasis-associated protein MTA1;
GN   Name=MTA1;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033363; P:secretory granule organization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MTA2_HUMAN              Reviewed;         668 AA.
AC   O94776; Q9UQB5;
DE   RecName: Full=Metastasis-associated protein MTA2;
DE   AltName: Full=Metastasis-associated 1-like 1;
DE            Short=MTA1-L1 protein;
DE   AltName: Full=p53 target protein in deacetylase complex;
GN   Name=MTA2; Synonyms=MTA1L1, PID;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0004407; F:histone deacetylase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006333; P:chromatin assembly or disassembly; TAS:ProtInc.
DR   GO; GO:0006306; P:DNA methylation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   MTA3_HUMAN              Reviewed;         594 AA.
AC   Q9BTC8; Q9NSP2; Q9ULF4;
DE   RecName: Full=Metastasis-associated protein MTA3;
GN   Name=MTA3; Synonyms=KIAA1266;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
//
ID   MTA70_HUMAN             Reviewed;         580 AA.
AC   Q86U44; O14736; Q86V05; Q9HB32;
DE   RecName: Full=N6-adenosine-methyltransferase 70 kDa subunit;
DE            Short=MT-A70;
DE            EC=2.1.1.62;
DE   AltName: Full=Methyltransferase-like protein 3;
GN   Name=METTL3; Synonyms=MTA70;
DR   GO; GO:0016422; F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0061157; P:mRNA destabilization; ISS:UniProtKB.
DR   GO; GO:0080009; P:mRNA methylation; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; ISS:UniProtKB.
DR   GO; GO:0001510; P:RNA methylation; IMP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
//
ID   MTAP2_HUMAN             Reviewed;        1827 AA.
AC   P11137; Q17S04; Q8IUX2; Q99975; Q99976;
DE   RecName: Full=Microtubule-associated protein 2;
DE            Short=MAP-2;
GN   Name=MAP2;
DR   GO; GO:0002162; F:dystroglycan binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEP:DFLAT.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEP:DFLAT.
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEP:DFLAT.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
//
ID   MTAP_HUMAN              Reviewed;         283 AA.
AC   Q13126; I2G7M5; I2G7M6; I2G7M7; I2G7M8; I2G7M9; I2G7N0; Q5T3P3;
AC   Q9H010;
DE   RecName: Full=S-methyl-5'-thioadenosine phosphorylase;
DE            EC=2.4.2.28;
DE   AltName: Full=5'-methylthioadenosine phosphorylase;
DE            Short=MTA phosphorylase;
DE            Short=MTAP;
DE            Short=MTAPase;
GN   Name=MTAP; Synonyms=MSAP;
DR   GO; GO:0004645; F:phosphorylase activity; TAS:ProtInc.
DR   GO; GO:0017061; F:S-methyl-5-thioadenosine phosphorylase activity; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; TAS:Reactome.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   MTBP_HUMAN              Reviewed;         904 AA.
AC   Q96DY7; Q9HA89;
DE   RecName: Full=Mdm2-binding protein;
DE            Short=hMTBP;
GN   Name=MTBP;
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007089; P:traversing start control point of mitotic cell cycle; IEA:Ensembl.
//
ID   MTCH1_HUMAN             Reviewed;         389 AA.
AC   Q9NZJ7; A8KAX5; B2RCE3; Q6PK60; Q6UX45; Q7L465; Q9BW23; Q9NZR6;
AC   Q9UJZ5;
DE   RecName: Full=Mitochondrial carrier homolog 1;
DE   AltName: Full=Presenilin-associated protein;
GN   Name=MTCH1; Synonyms=PSAP; ORFNames=CGI-64, UNQ1871/PRO4314;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045161; P:neuronal ion channel clustering; NAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEP:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MTCH2_HUMAN             Reviewed;         303 AA.
AC   Q9Y6C9; B2R7L8;
DE   RecName: Full=Mitochondrial carrier homolog 2;
DE   AltName: Full=Met-induced mitochondrial protein;
GN   Name=MTCH2; Synonyms=MIMP; ORFNames=HSPC032;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   MTCL1_HUMAN             Reviewed;        1905 AA.
AC   Q9Y4B5; E9PAY7; Q6ZMQ9; Q8IWA9;
DE   RecName: Full=Microtubule cross-linking factor 1;
DE   AltName: Full=Coiled-coil domain-containing protein 165;
DE   AltName: Full=PAR-1-interacting protein;
DE   AltName: Full=SOGA family member 2;
GN   Name=MTCL1; Synonyms=CCDC165, KIAA0802, SOGA2;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.
DR   GO; GO:2000576; P:positive regulation of microtubule motor activity; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
//
ID   MTCP1_HUMAN             Reviewed;         107 AA.
AC   P56278; Q5HYP2;
DE   RecName: Full=Protein p13 MTCP-1;
DE            Short=p13MTCP1;
DE   AltName: Full=Mature T-cell proliferation-1 type B1;
DE            Short=MTCP-1 type B1;
GN   Name=MTCP1; Synonyms=C6.1B;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
//
ID   MTD2L_HUMAN             Reviewed;         347 AA.
AC   Q9H903; Q6P079; Q8N560;
DE   RecName: Full=Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2;
DE   AltName: Full=NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein;
DE            Short=MTHFD2-like;
DE   Includes:
DE     RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase;
DE              EC=1.5.1.15;
DE   Includes:
DE     RecName: Full=Methenyltetrahydrofolate cyclohydrolase;
DE              EC=3.5.4.9;
GN   Name=MTHFD2L;
DR   GO; GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IBA:RefGenome.
DR   GO; GO:0004487; F:methylenetetrahydrofolate dehydrogenase (NAD+) activity; IBA:RefGenome.
DR   GO; GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IBA:RefGenome.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006730; P:one-carbon metabolic process; IBA:RefGenome.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
//
ID   MTDC_HUMAN              Reviewed;         350 AA.
AC   P13995; Q53G90; Q53GV5; Q53S36;
DE   RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial;
DE   Includes:
DE     RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase;
DE              EC=1.5.1.15;
DE   Includes:
DE     RecName: Full=Methenyltetrahydrofolate cyclohydrolase;
DE              EC=3.5.4.9;
DE   Flags: Precursor;
GN   Name=MTHFD2; Synonyms=NMDMC;
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; ISS:UniProtKB.
DR   GO; GO:0004487; F:methylenetetrahydrofolate dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IDA:UniProtKB.
DR   GO; GO:0042301; F:phosphate ion binding; IDA:UniProtKB.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IBA:RefGenome.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IDA:UniProtKB.
//
ID   MTER1_HUMAN             Reviewed;         417 AA.
AC   Q96E29; B3KMG6; G3V130; Q9Y301;
DE   RecName: Full=mTERF domain-containing protein 1, mitochondrial;
DE   AltName: Full=Mitochondrial transcription termination factor 3;
DE            Short=mTERF3;
DE   Flags: Precursor;
GN   Name=MTERFD1; ORFNames=CGI-12;
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MTER2_HUMAN             Reviewed;         381 AA.
AC   Q7Z6M4; A8K6K0; Q9P0E0;
DE   RecName: Full=mTERF domain-containing protein 2;
DE   AltName: Full=Mitochondrial transcription termination factor 4;
DE            Short=MTERF4;
DE   Contains:
DE     RecName: Full=mTERF domain-containing protein 2 processed;
DE   Flags: Precursor;
GN   Name=MTERFD2; ORFNames=HSPC096;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IDA:MGI.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IEA:Ensembl.
DR   GO; GO:0042255; P:ribosome assembly; IEA:Ensembl.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IEA:Ensembl.
//
ID   MTER3_HUMAN             Reviewed;         385 AA.
AC   Q49AM1; Q53HM2; Q9H4L6; Q9H7Y9;
DE   RecName: Full=mTERF domain-containing protein 3, mitochondrial;
DE   AltName: Full=Mitochondrial transcription termination factor 2;
DE            Short=mTERF2;
DE            Short=mTERFL;
DE   AltName: Full=Mitochondrial transcription termination factor-like protein;
DE   Flags: Precursor;
GN   Name=MTERFD3;
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:UniProtKB.
//
ID   MTERF_HUMAN             Reviewed;         399 AA.
AC   Q99551; A4D1E3; Q32NF8; Q53H51; Q9BVR7;
DE   RecName: Full=Transcription termination factor, mitochondrial;
DE   AltName: Full=Mitochondrial transcription termination factor 1;
DE            Short=mTERF;
DE            Short=mTERF1;
DE   Flags: Precursor;
GN   Name=MTERF;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032392; P:DNA geometric change; IDA:UniProtKB.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006393; P:termination of mitochondrial transcription; IDA:UniProtKB.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; TAS:Reactome.
//
ID   MTF1_HUMAN              Reviewed;         753 AA.
AC   Q14872; B2RAK6; Q96CB1;
DE   RecName: Full=Metal regulatory transcription factor 1;
DE   AltName: Full=MRE-binding transcription factor;
DE   AltName: Full=Transcription factor MTF-1;
GN   Name=MTF1;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0010038; P:response to metal ion; TAS:ProtInc.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MTF2_HUMAN              Reviewed;         593 AA.
AC   Q9Y483; A6NGQ9; A8K2Q3; B1AKT5; B1AKT6; Q9UES9; Q9UP40;
DE   RecName: Full=Metal-response element-binding transcription factor 2;
DE   AltName: Full=Metal regulatory transcription factor 2;
DE   AltName: Full=Metal-response element DNA-binding protein M96;
DE   AltName: Full=Polycomb-like protein 2;
DE            Short=hPCl2;
GN   Name=MTF2; Synonyms=PCL2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0061086; P:negative regulation of histone H3-K27 methylation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0061087; P:positive regulation of histone H3-K27 methylation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0007379; P:segment specification; ISS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
//
ID   MTFP1_HUMAN             Reviewed;         166 AA.
AC   Q9UDX5; A6NFQ5; Q9H3K1; Q9P0N6;
DE   RecName: Full=Mitochondrial fission process protein 1;
DE   AltName: Full=Mitochondrial 18 kDa protein;
DE            Short=MTP18;
GN   Name=MTFP1; Synonyms=MTP18; ORFNames=HSPC242, My022;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000266; P:mitochondrial fission; IMP:UniProtKB.
//
ID   MTFR1_HUMAN             Reviewed;         333 AA.
AC   Q15390; E7EP84; Q6IB94; Q7Z669; Q86XH5; Q8IVD7;
DE   RecName: Full=Mitochondrial fission regulator 1;
DE   AltName: Full=Chondrocyte protein with a poly-proline region;
DE   Flags: Precursor;
GN   Name=MTFR1; Synonyms=CHPPR, FAM54A2, KIAA0009;
DR   GO; GO:0009060; P:aerobic respiration; ISS:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
//
ID   MTFR2_HUMAN             Reviewed;         385 AA.
AC   Q6P444; A8K8D8; E1P585; Q5JWR7; Q6ZUE8; Q7L3U6; Q9BZ39;
DE   RecName: Full=Mitochondrial fission regulator 2;
DE   AltName: Full=DUF729 domain-containing protein 1;
GN   Name=MTFR2; Synonyms=DUFD1, FAM54A;
DR   GO; GO:0009060; P:aerobic respiration; ISS:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
//
ID   MTG16_HUMAN             Reviewed;         653 AA.
AC   O75081; D3DX78; O60615; O60616; O60617; O75082; O75107; O75108;
AC   Q0P5Z6; Q6P5W6;
DE   RecName: Full=Protein CBFA2T3;
DE   AltName: Full=MTG8-related protein 2;
DE   AltName: Full=Myeloid translocation gene on chromosome 16 protein;
DE            Short=hMTG16;
DE   AltName: Full=Zinc finger MYND domain-containing protein 4;
GN   Name=CBFA2T3; Synonyms=MTG16, MTGR2, ZMYND4;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0030851; P:granulocyte differentiation; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MTG1_HUMAN              Reviewed;         334 AA.
AC   Q9BT17; Q5VWX8; Q6PIY9; Q8IYJ4; Q8NC48; Q9BVU8;
DE   RecName: Full=Mitochondrial ribosome-associated GTPase 1;
DE   AltName: Full=GTP-binding protein 7;
DE   AltName: Full=Mitochondrial GTPase 1;
DE   Flags: Precursor;
GN   Name=MTG1; Synonyms=GTPBP7;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0070129; P:regulation of mitochondrial translation; IMP:UniProtKB.
DR   GO; GO:0044065; P:regulation of respiratory system process; IMP:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
//
ID   MTG2_HUMAN              Reviewed;         406 AA.
AC   Q9H4K7; A6NDR3; Q96I17; Q9NVG9; Q9UFR4;
DE   RecName: Full=Mitochondrial ribosome-associated GTPase 2;
DE   AltName: Full=GTP-binding protein 5;
DE   AltName: Full=Protein obg homolog 1;
DE            Short=ObgH1;
GN   Name=MTG2; Synonyms=GTPBP5, OBGH1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0070129; P:regulation of mitochondrial translation; IMP:UniProtKB.
DR   GO; GO:0044065; P:regulation of respiratory system process; IMP:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   MTG8_HUMAN              Reviewed;         604 AA.
AC   Q06455; B7Z4P4; E7EPN4; O14784; Q06456; Q14873; Q16239; Q16346;
AC   Q16347; Q6IBL1; Q6NXH1; Q7Z4J5; Q92479; Q9BRZ0;
DE   RecName: Full=Protein CBFA2T1;
DE   AltName: Full=Cyclin-D-related protein;
DE   AltName: Full=Eight twenty one protein;
DE   AltName: Full=Protein ETO;
DE   AltName: Full=Protein MTG8;
DE   AltName: Full=Zinc finger MYND domain-containing protein 2;
GN   Name=RUNX1T1; Synonyms=AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0051101; P:regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MTG8R_HUMAN             Reviewed;         604 AA.
AC   O43439; B2RAE6; F8W6D7; Q5TGE4; Q5TGE5; Q5TGE6; Q5TGE7; Q8IWF3;
AC   Q96B06; Q96L00; Q9H436; Q9UJP8; Q9UJP9; Q9UP24;
DE   RecName: Full=Protein CBFA2T2;
DE   AltName: Full=ETO homologous on chromosome 20;
DE   AltName: Full=MTG8-like protein;
DE   AltName: Full=MTG8-related protein 1;
DE   AltName: Full=Myeloid translocation-related protein 1;
DE   AltName: Full=p85;
GN   Name=CBFA2T2; Synonyms=EHT, MTGR1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   MTHFS_HUMAN             Reviewed;         203 AA.
AC   P49914; H3BQ75;
DE   RecName: Full=5-formyltetrahydrofolate cyclo-ligase;
DE            EC=6.3.3.2;
DE   AltName: Full=5,10-methenyl-tetrahydrofolate synthetase;
DE            Short=MTHFS;
DE            Short=Methenyl-THF synthetase;
GN   Name=MTHFS;
DR   GO; GO:0030272; F:5-formyltetrahydrofolate cyclo-ligase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   GO; GO:0015942; P:formate metabolic process; NAS:UniProtKB.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IDA:UniProtKB.
//
ID   MTHR_HUMAN              Reviewed;         656 AA.
AC   P42898; B2R7A6; Q5SNW6; Q5SNW9; Q7Z6M6; Q8IU73; Q9UQR2;
DE   RecName: Full=Methylenetetrahydrofolate reductase;
DE            EC=1.5.1.20;
GN   Name=MTHFR;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0004489; F:methylenetetrahydrofolate reductase (NAD(P)H) activity; TAS:Reactome.
DR   GO; GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0033274; P:response to vitamin B2; IEA:Ensembl.
DR   GO; GO:0046500; P:S-adenosylmethionine metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MTHSD_HUMAN             Reviewed;         383 AA.
AC   Q2M296; A8MQ77; B7ZLC0; B7ZLC2; D3DUM9; E9PAM1; Q9H878; Q9H954;
DE   RecName: Full=Methenyltetrahydrofolate synthase domain-containing protein;
GN   Name=MTHFSD;
DR   GO; GO:0030272; F:5-formyltetrahydrofolate cyclo-ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
//
ID   MTL5_HUMAN              Reviewed;         508 AA.
AC   Q9Y4I5; A8K8J3; Q4G182; Q6P2E2; Q8NCC8;
DE   RecName: Full=Tesmin;
DE   AltName: Full=Metallothionein-like 5, testis-specific;
DE   AltName: Full=Testis-specific metallothionein-like protein;
GN   Name=MTL5;
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006875; P:cellular metal ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0010038; P:response to metal ion; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   MTLR_HUMAN              Reviewed;         412 AA.
AC   O43193;
DE   RecName: Full=Motilin receptor;
DE   AltName: Full=G-protein coupled receptor 38;
GN   Name=MLNR; Synonyms=GPR38, MTLR, MTLR1;
DR   GuidetoPHARMACOLOGY; 297; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0016520; F:growth hormone-releasing hormone receptor activity; IEA:InterPro.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   MTM1_HUMAN              Reviewed;         603 AA.
AC   Q13496; A6NDB1; Q8NEL1;
DE   RecName: Full=Myotubularin;
DE            EC=3.1.3.64;
GN   Name=MTM1; Synonyms=CG2;
DR   GO; GO:0019215; F:intermediate filament binding; IDA:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0052629; F:phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008333; P:endosome to lysosome transport; IDA:UniProtKB.
DR   GO; GO:0045109; P:intermediate filament organization; IMP:UniProtKB.
DR   GO; GO:0048311; P:mitochondrion distribution; IMP:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IDA:UniProtKB.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0044088; P:regulation of vacuole organization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTMR1_HUMAN             Reviewed;         665 AA.
AC   Q13613; Q9UBX6; Q9UEM0; Q9UQD5;
DE   RecName: Full=Myotubularin-related protein 1;
DE            EC=3.1.3.-;
GN   Name=MTMR1;
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTMR2_HUMAN             Reviewed;         643 AA.
AC   Q13614; A6NN98; Q9UPS9;
DE   RecName: Full=Myotubularin-related protein 2;
DE            EC=3.1.3.-;
GN   Name=MTMR2; Synonyms=KIAA1073;
DR   GO; GO:0052866; F:phosphatidylinositol phosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0097062; P:dendritic spine maintenance; ISS:BHF-UCL.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IEA:Ensembl.
DR   GO; GO:0032288; P:myelin assembly; IEA:Ensembl.
DR   GO; GO:0045806; P:negative regulation of endocytosis; ISS:BHF-UCL.
DR   GO; GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0031642; P:negative regulation of myelination; IEA:Ensembl.
DR   GO; GO:2000645; P:negative regulation of receptor catabolic process; ISS:BHF-UCL.
DR   GO; GO:0002091; P:negative regulation of receptor internalization; ISS:BHF-UCL.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:2000643; P:positive regulation of early endosome to late endosome transport; ISS:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; NAS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTMR3_HUMAN             Reviewed;        1198 AA.
AC   Q13615; A5PL26; A7MD32; Q9NYN5; Q9NYN6; Q9UDX6; Q9UEG3;
DE   RecName: Full=Myotubularin-related protein 3;
DE            EC=3.1.3.48;
DE   AltName: Full=FYVE domain-containing dual specificity protein phosphatase 1;
DE            Short=FYVE-DSP1;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 10;
GN   Name=MTMR3; Synonyms=KIAA0371, ZFYVE10;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTMR4_HUMAN             Reviewed;        1195 AA.
AC   Q9NYA4; D3DTZ6; Q8IV27; Q9Y4D5;
DE   RecName: Full=Myotubularin-related protein 4;
DE            EC=3.1.3.48;
DE   AltName: Full=FYVE domain-containing dual specificity protein phosphatase 2;
DE            Short=FYVE-DSP2;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 11;
GN   Name=MTMR4; Synonyms=KIAA0647, ZFYVE11;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   MTMR5_HUMAN             Reviewed;        1867 AA.
AC   O95248; A6PVG9; O60228; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8;
DE   RecName: Full=Myotubularin-related protein 5;
DE   AltName: Full=SET-binding factor 1;
DE            Short=Sbf1;
GN   Name=SBF1; Synonyms=MTMR5;
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; TAS:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   MTMR6_HUMAN             Reviewed;         621 AA.
AC   Q9Y217; B2RBB5; B3KSB4; Q5JRG6; Q86TB7; Q86YH4; Q96P80;
DE   RecName: Full=Myotubularin-related protein 6;
DE            EC=3.1.3.-;
GN   Name=MTMR6;
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; NAS:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTMR7_HUMAN             Reviewed;         660 AA.
AC   Q9Y216; A1L4K9; B4DG87; Q68DX4;
DE   RecName: Full=Myotubularin-related protein 7;
DE            EC=3.1.3.-;
GN   Name=MTMR7;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTMR8_HUMAN             Reviewed;         704 AA.
AC   Q96EF0; Q5JT99; Q9NXP6;
DE   RecName: Full=Myotubularin-related protein 8;
DE            EC=3.1.3.-;
GN   Name=MTMR8;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
//
ID   MTMR9_HUMAN             Reviewed;         549 AA.
AC   Q96QG7; Q52LU3; Q8WW11; Q96QG6; Q9NX50;
DE   RecName: Full=Myotubularin-related protein 9;
GN   Name=MTMR9; Synonyms=C8orf9, MTMR8;
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:Ensembl.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   MTMRA_HUMAN             Reviewed;         777 AA.
AC   Q9NXD2; Q6P4Q6;
DE   RecName: Full=Myotubularin-related protein 10;
GN   Name=MTMR10;
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
//
ID   MTMRB_HUMAN             Reviewed;         709 AA.
AC   A4FU01; B3KUE4; B4DJI6; B4DQF5; B4E3Q6; Q3ZCP7; Q5SZ62; Q6P2Q8;
AC   Q99752; Q99753;
DE   RecName: Full=Myotubularin-related protein 11;
DE   AltName: Full=Cisplatin resistance-associated protein;
DE            Short=hCRA;
GN   Name=MTMR11;
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
//
ID   MTMRC_HUMAN             Reviewed;         747 AA.
AC   Q9C0I1; Q69YJ4; Q6PFW3; Q96QU2; Q9NX27;
DE   RecName: Full=Myotubularin-related protein 12;
DE   AltName: Full=Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit;
DE            Short=3-PAP;
DE            Short=3-phosphatase adapter protein;
GN   Name=MTMR12; Synonyms=KIAA1682, PIP3AP;
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MTMRD_HUMAN             Reviewed;        1849 AA.
AC   Q86WG5; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2;
AC   Q96FE2; Q9C097;
DE   RecName: Full=Myotubularin-related protein 13;
DE   AltName: Full=SET-binding factor 2;
GN   Name=SBF2; Synonyms=CMT4B2, KIAA1766, MTMR13;
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   GO; GO:0019208; F:phosphatase regulator activity; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0042552; P:myelination; NAS:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IEA:Ensembl.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   MTMRE_HUMAN             Reviewed;         650 AA.
AC   Q8NCE2; Q0JTH5; Q0JU83; Q6PIZ4; Q6QE21; Q86VK9; Q8IYK1; Q8TCM7;
AC   Q9H6C0;
DE   RecName: Full=Myotubularin-related protein 14;
DE            EC=3.1.3.-;
DE   AltName: Full=HCV NS5A-transactivated protein 4 splice variant A-binding protein 1;
DE            Short=NS5ATP4ABP1;
DE   AltName: Full=hJumpy;
GN   Name=MTMR14; Synonyms=C3orf29;
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MTNA_HUMAN              Reviewed;         369 AA.
AC   Q9BV20; Q8NDC9;
DE   RecName: Full=Methylthioribose-1-phosphate isomerase;
DE            Short=M1Pi;
DE            Short=MTR-1-P isomerase;
DE            EC=5.3.1.23;
DE   AltName: Full=Mediator of RhoA-dependent invasion;
DE   AltName: Full=S-methyl-5-thioribose-1-phosphate isomerase;
DE   AltName: Full=Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein;
GN   Name=MRI1; Synonyms=MRDI; ORFNames=UNQ6390/PRO21135;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IBA:RefGenome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019284; P:L-methionine biosynthetic process from S-adenosylmethionine; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; IBA:RefGenome.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   MTNB_HUMAN              Reviewed;         242 AA.
AC   Q96GX9; A8K9D3; Q6PJX6; Q8WVU2; Q96HK2; Q9Y318;
DE   RecName: Full=Methylthioribulose-1-phosphate dehydratase;
DE            Short=MTRu-1-P dehydratase;
DE            EC=4.2.1.109;
DE   AltName: Full=APAF1-interacting protein;
DE            Short=hAPIP;
GN   Name=APIP; ORFNames=CGI-29;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046570; F:methylthioribulose 1-phosphate dehydratase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019284; P:L-methionine biosynthetic process from S-adenosylmethionine; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   MTND_HUMAN              Reviewed;         179 AA.
AC   Q9BV57; D6W4Y3; Q53HW3; Q53QD3; Q57YV7; Q68CK2; Q6ZSF7; Q7Z512;
AC   Q96P85; Q9NV57;
DE   RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase;
DE            EC=1.13.11.54;
DE   AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring);
DE            Short=ARD;
DE            Short=Fe-ARD;
DE   AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1;
DE            Short=MTCBP-1;
DE   AltName: Full=Submergence-induced protein-like factor;
DE            Short=Sip-L;
GN   Name=ADI1; Synonyms=MTCBP1; ORFNames=HMFT1638;
DR   GO; GO:0010309; F:acireductone dioxygenase [iron(II)-requiring] activity; TAS:Reactome.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019509; P:L-methionine salvage from methylthioadenosine; IDA:UniProtKB.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   MTO1_HUMAN              Reviewed;         717 AA.
AC   Q9Y2Z2; B3KQB5; Q5SWL2; Q5SWL3; Q5SWL4; Q8NDN7; Q8WZ57; Q96FE6;
AC   Q9BS06;
DE   RecName: Full=Protein MTO1 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=MTO1; ORFNames=CGI-02;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0070899; P:mitochondrial tRNA wobble uridine modification; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:InterPro.
//
ID   MTOR_HUMAN              Reviewed;        2549 AA.
AC   P42345; Q4LE76; Q5TER1; Q6LE87; Q96QG3; Q9Y4I3;
DE   RecName: Full=Serine/threonine-protein kinase mTOR;
DE            EC=2.7.11.1;
DE   AltName: Full=FK506-binding protein 12-rapamycin complex-associated protein 1;
DE   AltName: Full=FKBP12-rapamycin complex-associated protein;
DE   AltName: Full=Mammalian target of rapamycin;
DE            Short=mTOR;
DE   AltName: Full=Mechanistic target of rapamycin;
DE   AltName: Full=Rapamycin and FKBP12 target 1;
DE   AltName: Full=Rapamycin target protein 1;
GN   Name=MTOR; Synonyms=FRAP, FRAP1, FRAP2, RAFT1, RAPT1;
DR   GuidetoPHARMACOLOGY; 2109; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008144; F:drug binding; IEA:InterPro.
DR   GO; GO:0016301; F:kinase activity; TAS:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.
DR   GO; GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010507; P:negative regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0045792; P:negative regulation of cell size; IEA:Ensembl.
DR   GO; GO:0016242; P:negative regulation of macroautophagy; IEA:Ensembl.
DR   GO; GO:0051534; P:negative regulation of NFAT protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:MGI.
DR   GO; GO:0030163; P:protein catabolic process; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0043610; P:regulation of carbohydrate utilization; IEA:Ensembl.
DR   GO; GO:0031998; P:regulation of fatty acid beta-oxidation; IEA:Ensembl.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0032095; P:regulation of response to food; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IDA:UniProtKB.
DR   GO; GO:0007584; P:response to nutrient; NAS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IMP:UniProtKB.
DR   GO; GO:0031529; P:ruffle organization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0031929; P:TOR signaling; IMP:UniProtKB.
//
ID   MTPN_HUMAN              Reviewed;         118 AA.
AC   P58546;
DE   RecName: Full=Myotrophin;
DE   AltName: Full=Protein V-1;
GN   Name=MTPN;
DR   GO; GO:0006584; P:catecholamine metabolic process; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; NAS:UniProtKB.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.
DR   GO; GO:2000812; P:regulation of barbed-end actin filament capping; IDA:UniProtKB.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; NAS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; NAS:UniProtKB.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
//
ID   MTP_HUMAN               Reviewed;         894 AA.
AC   P55157; A8K428; Q08AM4;
DE   RecName: Full=Microsomal triglyceride transfer protein large subunit;
DE   Flags: Precursor;
GN   Name=MTTP; Synonyms=MTP;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005319; F:lipid transporter activity; TAS:Reactome.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0042953; P:lipoprotein transport; IEA:Ensembl.
DR   GO; GO:0006497; P:protein lipidation; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   MTR1A_HUMAN             Reviewed;         350 AA.
AC   P48039; A0AVC5; B0M0L2;
DE   RecName: Full=Melatonin receptor type 1A;
DE            Short=Mel-1A-R;
DE            Short=Mel1a receptor;
GN   Name=MTNR1A;
DR   GuidetoPHARMACOLOGY; 287; -.
DR   GO; GO:0042562; F:hormone binding; IPI:BHF-UCL.
DR   GO; GO:0008502; F:melatonin receptor activity; TAS:ProtInc.
DR   GO; GO:0097159; F:organic cyclic compound binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007617; P:mating behavior; TAS:ProtInc.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IDA:BHF-UCL.
//
ID   MTR1B_HUMAN             Reviewed;         362 AA.
AC   P49286;
DE   RecName: Full=Melatonin receptor type 1B;
DE            Short=Mel-1B-R;
DE            Short=Mel1b receptor;
GN   Name=MTNR1B;
DR   GuidetoPHARMACOLOGY; 288; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008502; F:melatonin receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   MTR1L_HUMAN             Reviewed;         617 AA.
AC   Q13585; Q0VGG3; Q3ZAR0;
DE   RecName: Full=Melatonin-related receptor;
DE   AltName: Full=G protein-coupled receptor 50;
DE   AltName: Full=H9;
GN   Name=GPR50;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008502; F:melatonin receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   MTRR_HUMAN              Reviewed;         725 AA.
AC   Q9UBK8; O60471; Q32MA9; Q7Z4M8;
DE   RecName: Full=Methionine synthase reductase;
DE            Short=MSR;
DE            EC=1.16.1.8;
GN   Name=MTRR;
DR   GO; GO:0030586; F:[methionine synthase] reductase activity; TAS:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0010181; F:FMN binding; TAS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; TAS:UniProtKB.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:RefGenome.
DR   GO; GO:0016723; F:oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0006306; P:DNA methylation; ISS:UniProtKB.
DR   GO; GO:0046655; P:folic acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006555; P:methionine metabolic process; TAS:UniProtKB.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   MTSS1_HUMAN             Reviewed;         755 AA.
AC   O43312; J3KNK6; Q8TCA2; Q96RX2;
DE   RecName: Full=Metastasis suppressor protein 1;
DE   AltName: Full=Metastasis suppressor YGL-1;
DE   AltName: Full=Missing in metastasis protein;
GN   Name=MTSS1; Synonyms=KIAA0429, MIM;
DR   GO; GO:0003785; F:actin monomer binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0071498; P:cellular response to fluid shear stress; ISS:UniProtKB.
DR   GO; GO:2001013; P:epithelial cell proliferation involved in renal tubule morphogenesis; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IEA:InterPro.
DR   GO; GO:0072102; P:glomerulus morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030035; P:microspike assembly; NAS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0072160; P:nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0061333; P:renal tubule morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:UniProtKB.
//
ID   MTSSL_HUMAN             Reviewed;         747 AA.
AC   Q765P7; A6NJI7; Q9BUA8;
DE   RecName: Full=MTSS1-like protein;
DE   AltName: Full=Actin-bundling with BAIAP2 homology protein 1;
DE            Short=ABBA-1;
GN   Name=MTSS1L;
DR   GO; GO:0046847; P:filopodium assembly; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   MTU1_HUMAN              Reviewed;         421 AA.
AC   O75648; A8K3U7; Q05C99; Q5W9C8; Q66K31; Q6ICC3; Q9NWC1;
DE   RecName: Full=Mitochondrial tRNA-specific 2-thiouridylase 1;
DE            EC=2.8.1.-;
DE   AltName: Full=MTO2 homolog;
GN   Name=TRMU; Synonyms=MTU1, TRMT1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   MTURN_HUMAN             Reviewed;         131 AA.
AC   Q8N3F0; B8ZZW9; Q8N791; Q8N8M4; Q8NEX2;
DE   RecName: Full=Maturin;
DE   AltName: Full=Maturin neural progenitor differentiation regulator protein homolog;
DE   AltName: Full=Protein Ells1;
GN   Name=MTURN; Synonyms=C7orf41;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   MTUS1_HUMAN             Reviewed;        1270 AA.
AC   Q9ULD2; A8K135; B2RBJ6; B3KWJ9; B4DH03; B9EGA1; D3DSP8; Q63HJ6;
AC   Q659F4; Q6PK49; Q6URW7; Q8N4M6; Q8WTT9; Q9H7T2;
DE   RecName: Full=Microtubule-associated tumor suppressor 1;
DE   AltName: Full=AT2 receptor-binding protein;
DE   AltName: Full=Angiotensin-II type 2 receptor-interacting protein;
DE   AltName: Full=Mitochondrial tumor suppressor 1;
GN   Name=MTUS1; Synonyms=ATBP, ATIP, GK1, KIAA1288, MTSG1;
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
//
ID   MTUS2_HUMAN             Reviewed;        1369 AA.
AC   Q5JR59; A7E292; B4DF81; O94872; Q08E97; Q5JQR3; Q8N5E2;
DE   RecName: Full=Microtubule-associated tumor suppressor candidate 2;
DE   AltName: Full=Cardiac zipper protein;
DE   AltName: Full=Microtubule plus-end tracking protein TIP150;
DE            Short=Tracking protein of 150 kDa;
GN   Name=MTUS2; Synonyms=CAZIP, KIAA0774, TIP150;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
//
ID   MTX1_HUMAN              Reviewed;         466 AA.
AC   Q13505; B1AVR9; B1AVS0; B2R9P4; Q9BUU3;
DE   RecName: Full=Metaxin-1;
DE   AltName: Full=Mitochondrial outer membrane import complex protein 1;
GN   Name=MTX1; Synonyms=MTX, MTXN;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   MTX3_HUMAN              Reviewed;         312 AA.
AC   Q5HYI7; B4DL65; E9PB57; Q7Z380; Q8NB92;
DE   RecName: Full=Metaxin-3;
GN   Name=MTX3;
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IEA:InterPro.
//
ID   MTX2_HUMAN              Reviewed;         263 AA.
AC   O75431; A8JZZ4; Q53S50; Q53SQ2; Q5M7Z6; Q8IZ68;
DE   RecName: Full=Metaxin-2;
DE   AltName: Full=Mitochondrial outer membrane import complex protein 2;
GN   Name=MTX2;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006839; P:mitochondrial transport; TAS:ProtInc.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IEA:InterPro.
//
ID   MUC12_HUMAN             Reviewed;        5478 AA.
AC   Q9UKN1; A6ND38; Q9UKN0;
DE   RecName: Full=Mucin-12;
DE            Short=MUC-12;
DE   AltName: Full=Mucin-11;
DE            Short=MUC-11;
DE   Flags: Precursor;
GN   Name=MUC12; Synonyms=MUC11;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   MUC13_HUMAN             Reviewed;         512 AA.
AC   Q9H3R2; Q6UWD9; Q9NXT5;
DE   RecName: Full=Mucin-13;
DE            Short=MUC-13;
DE   AltName: Full=Down-regulated in colon cancer 1;
DE   Flags: Precursor;
GN   Name=MUC13; Synonyms=DRCC1, RECC; ORFNames=UNQ6194/PRO20221;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProt.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC15_HUMAN             Reviewed;         334 AA.
AC   Q8N387; B3KY00; Q6UWS3; Q8IXI8; Q8WW41;
DE   RecName: Full=Mucin-15;
DE            Short=MUC-15;
DE   Flags: Precursor;
GN   Name=MUC15; ORFNames=UNQ750/PRO1481;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC16_HUMAN             Reviewed;       22152 AA.
AC   Q8WXI7; Q6ZQW5; Q96RK2;
DE   RecName: Full=Mucin-16;
DE            Short=MUC-16;
DE   AltName: Full=Ovarian cancer-related tumor marker CA125;
DE            Short=CA-125;
DE   AltName: Full=Ovarian carcinoma antigen CA125;
GN   Name=MUC16; Synonyms=CA125;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC17_HUMAN             Reviewed;        4493 AA.
AC   Q685J3; O14761; Q685J2; Q8TDH7;
DE   RecName: Full=Mucin-17;
DE            Short=MUC-17;
DE   AltName: Full=Small intestinal mucin-3;
DE            Short=MUC-3;
DE   Flags: Precursor;
GN   Name=MUC17; Synonyms=MUC3;
DR   GO; GO:0030197; F:extracellular matrix constituent, lubricant activity; NAS:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC18_HUMAN             Reviewed;         646 AA.
AC   P43121; O95812; Q59E86; Q6PHR3; Q6ZTR2;
DE   RecName: Full=Cell surface glycoprotein MUC18;
DE   AltName: Full=Cell surface glycoprotein P1H12;
DE   AltName: Full=Melanoma cell adhesion molecule;
DE   AltName: Full=Melanoma-associated antigen A32;
DE   AltName: Full=Melanoma-associated antigen MUC18;
DE   AltName: Full=S-endo 1 endothelial-associated antigen;
DE   AltName: CD_antigen=CD146;
DE   Flags: Precursor;
GN   Name=MCAM; Synonyms=MUC18;
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0003094; P:glomerular filtration; IEP:UniProtKB.
DR   GO; GO:0061042; P:vascular wound healing; IEP:UniProtKB.
//
ID   MUC19_HUMAN             Reviewed;        6254 AA.
AC   Q7Z5P9; Q8NA85;
DE   RecName: Full=Mucin-19;
DE            Short=MUC-19;
DE   Flags: Precursor;
GN   Name=MUC19;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC1_HUMAN              Reviewed;        1255 AA.
AC   P15941; A5YRV1; A6ZID9; A6ZIE0; B1AVQ8; B1AVR0; B6ECA1; E7ESE5;
AC   E7EUG9; P13931; P15942; P17626; Q0VAP5; Q0VAP6; Q14128; Q14876;
AC   Q16437; Q16442; Q16615; Q6S4Y3; Q7Z547; Q7Z548; Q7Z550; Q7Z552;
AC   Q9BXA4; Q9UE75; Q9UE76; Q9UQL1; Q9Y4J2;
DE   RecName: Full=Mucin-1;
DE            Short=MUC-1;
DE   AltName: Full=Breast carcinoma-associated antigen DF3;
DE   AltName: Full=Cancer antigen 15-3;
DE            Short=CA 15-3;
DE   AltName: Full=Carcinoma-associated mucin;
DE   AltName: Full=Episialin;
DE   AltName: Full=H23AG;
DE   AltName: Full=Krebs von den Lungen-6;
DE            Short=KL-6;
DE   AltName: Full=PEMT;
DE   AltName: Full=Peanut-reactive urinary mucin;
DE            Short=PUM;
DE   AltName: Full=Polymorphic epithelial mucin;
DE            Short=PEM;
DE   AltName: Full=Tumor-associated epithelial membrane antigen;
DE            Short=EMA;
DE   AltName: Full=Tumor-associated mucin;
DE   AltName: CD_antigen=CD227;
DE   Contains:
DE     RecName: Full=Mucin-1 subunit alpha;
DE              Short=MUC1-NT;
DE              Short=MUC1-alpha;
DE   Contains:
DE     RecName: Full=Mucin-1 subunit beta;
DE              Short=MUC1-beta;
DE     AltName: Full=MUC1-CT;
DE   Flags: Precursor;
GN   Name=MUC1; Synonyms=PUM;
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0090240; P:positive regulation of histone H4 acetylation; IDA:BHF-UCL.
DR   GO; GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0043618; P:regulation of transcription from RNA polymerase II promoter in response to stress; IDA:BHF-UCL.
//
ID   MUC20_HUMAN             Reviewed;         709 AA.
AC   Q8N307; Q6UX97; Q76I83; Q76I85; Q86ST8; Q8NBY6; Q96KA1; Q9P2I8;
DE   RecName: Full=Mucin-20;
DE            Short=MUC-20;
DE   Flags: Precursor;
GN   Name=MUC20; Synonyms=KIAA1359; ORFNames=UNQ2782/PRO7170;
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:MGI.
//
ID   MUC21_HUMAN             Reviewed;         566 AA.
AC   Q5SSG8; B0UZT7; B4DQ55; C9JMK2; D9N007; Q0VGF1; Q3B7T2; Q5SS94;
AC   Q6UXC5;
DE   RecName: Full=Mucin-21;
DE            Short=MUC-21;
DE   AltName: Full=Epiglycanin;
DE   Flags: Precursor;
GN   Name=MUC21; Synonyms=C6orf205; ORFNames=UNQ697/PRO1342;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC22_HUMAN             Reviewed;        1773 AA.
AC   E2RYF6; H3BQR8;
DE   RecName: Full=Mucin-22;
DE   AltName: Full=Panbronchiolitis-related mucin-like protein 1;
DE   Flags: Precursor;
GN   Name=MUC22; Synonyms=G4, PBMUCL1;
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   MUC24_HUMAN             Reviewed;         197 AA.
AC   Q04900; B4DQ85; E1P5E7; E1P5E8; E1P5E9; O95413; Q5JSU6; Q9BPV0;
AC   Q9NR26;
DE   RecName: Full=Sialomucin core protein 24;
DE            Short=MUC-24;
DE   AltName: Full=Endolyn;
DE   AltName: Full=Multi-glycosylated core protein 24;
DE            Short=MGC-24;
DE            Short=MGC-24v;
DE   AltName: CD_antigen=CD164;
DE   Flags: Precursor;
GN   Name=CD164;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:MGI.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IDA:MGI.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MUC2_HUMAN              Reviewed;        5179 AA.
AC   Q02817; Q14878;
DE   RecName: Full=Mucin-2;
DE            Short=MUC-2;
DE   AltName: Full=Intestinal mucin-2;
DE   Flags: Precursor;
GN   Name=MUC2; Synonyms=SMUC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProt.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC3A_HUMAN             Reviewed;        2541 AA.
AC   Q02505; O14650; O14651; O43418; O43421; Q02506; Q6W763; Q9H3Q7;
AC   Q9UKW9; Q9UN93; Q9UN94; Q9UN95;
DE   RecName: Full=Mucin-3A;
DE            Short=MUC-3A;
DE   AltName: Full=Intestinal mucin-3A;
DE   Flags: Precursor;
GN   Name=MUC3A; Synonyms=MUC3;
DR   GO; GO:0030197; F:extracellular matrix constituent, lubricant activity; NAS:UniProtKB.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC3B_HUMAN             Reviewed;        1237 AA.
AC   Q9H195; Q6W762; Q7LDU5; Q9GZZ2; Q9UN95;
DE   RecName: Full=Mucin-3B;
DE            Short=MUC-3B;
DE   AltName: Full=Intestinal mucin-3B;
DE   Flags: Precursor; Fragments;
GN   Name=MUC3B;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC4_HUMAN              Reviewed;        2169 AA.
AC   Q99102; O95938; Q9GZM2; Q9GZV6; Q9H481; Q9H482; Q9H483; Q9H484;
AC   Q9H485; Q9H486; Q9H487; Q9H4D6; Q9H4D8; Q9NPJ0; Q9NY09; Q9NY75;
AC   Q9NY76; Q9NY77; Q9NY78; Q9NY79; Q9NY80; Q9NY81;
DE   RecName: Full=Mucin-4;
DE            Short=MUC-4;
DE   AltName: Full=Ascites sialoglycoprotein;
DE            Short=ASGP;
DE   AltName: Full=Pancreatic adenocarcinoma mucin;
DE   AltName: Full=Testis mucin;
DE   AltName: Full=Tracheobronchial mucin;
DE   Contains:
DE     RecName: Full=Mucin-4 alpha chain;
DE     AltName: Full=Ascites sialoglycoprotein 1;
DE              Short=ASGP-1;
DE   Contains:
DE     RecName: Full=Mucin-4 beta chain;
DE     AltName: Full=Ascites sialoglycoprotein 2;
DE              Short=ASGP-2;
DE   Flags: Precursor;
GN   Name=MUC4;
DR   GO; GO:0005176; F:ErbB-2 class receptor binding; TAS:ProtInc.
DR   GO; GO:0030197; F:extracellular matrix constituent, lubricant activity; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProt.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC5A_HUMAN             Reviewed;        5030 AA.
AC   P98088; O60460; O76065; Q13792; Q14425; Q658Q1; Q7M4S5; Q8N4M9;
AC   Q8WWQ3; Q8WWQ4; Q8WWQ5;
DE   RecName: Full=Mucin-5AC;
DE            Short=MUC-5AC;
DE   AltName: Full=Gastric mucin;
DE   AltName: Full=Lewis B blood group antigen;
DE            Short=LeB;
DE   AltName: Full=Major airway glycoprotein;
DE   AltName: Full=Mucin-5 subtype AC, tracheobronchial;
DE   AltName: Full=Tracheobronchial mucin;
DE            Short=TBM;
DE   Flags: Precursor; Fragments;
GN   Name=MUC5AC; Synonyms=MUC5;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043206; P:extracellular fibril organization; IDA:MGI.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC5B_HUMAN             Reviewed;        5762 AA.
AC   Q9HC84; O00447; O00573; O14985; O15494; O95291; O95451; Q14881;
AC   Q7M4S5; Q99552; Q9UE28;
DE   RecName: Full=Mucin-5B;
DE            Short=MUC-5B;
DE   AltName: Full=Cervical mucin;
DE   AltName: Full=High molecular weight salivary mucin MG1;
DE   AltName: Full=Mucin-5 subtype B, tracheobronchial;
DE   AltName: Full=Sublingual gland mucin;
DE   Flags: Precursor;
GN   Name=MUC5B; Synonyms=MUC5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC6_HUMAN              Reviewed;        2439 AA.
AC   Q6W4X9; O15329; Q14394; Q2TUQ5; Q4L207; Q8N8I1; Q8NAK1;
DE   RecName: Full=Mucin-6;
DE            Short=MUC-6;
DE   AltName: Full=Gastric mucin-6;
DE   Flags: Precursor;
GN   Name=MUC6;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; NAS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUC7_HUMAN              Reviewed;         377 AA.
AC   Q8TAX7; Q9UCD7; Q9UCD8;
DE   RecName: Full=Mucin-7;
DE            Short=MUC-7;
DE   AltName: Full=Apo-MG2;
DE   AltName: Full=Salivary mucin-7;
DE   Flags: Precursor;
GN   Name=MUC7; Synonyms=MG2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUCEN_HUMAN             Reviewed;         261 AA.
AC   Q9ULC0; A8K716; B4E347; Q8NEY5; Q8WWE7; Q9NRM8;
DE   RecName: Full=Endomucin;
DE   AltName: Full=Endomucin-2;
DE   AltName: Full=Gastric cancer antigen Ga34;
DE   AltName: Full=Mucin-14;
DE            Short=MUC-14;
DE   Flags: Precursor;
GN   Name=EMCN; Synonyms=EMCN2, MUC14;
//
ID   MUCB_HUMAN              Reviewed;         391 AA.
AC   P04220;
DE   RecName: Full=Ig mu heavy chain disease protein;
DE   AltName: Full=BOT;
DR   GO; GO:0003823; F:antigen binding; TAS:UniProtKB.
//
ID   MUCL1_HUMAN             Reviewed;          90 AA.
AC   Q96DR8; Q0VG95; Q32ZB5;
DE   RecName: Full=Mucin-like protein 1;
DE   AltName: Full=Protein BS106;
DE   AltName: Full=Small breast epithelial mucin;
DE   Flags: Precursor;
GN   Name=MUCL1; Synonyms=SBEM; ORFNames=UNQ590/PRO1160;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   MUL1_HUMAN              Reviewed;         352 AA.
AC   Q969V5; B5M497; Q7Z431; Q9H9B5;
DE   RecName: Full=Mitochondrial ubiquitin ligase activator of NFKB 1;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 SUMO-protein ligase MUL1;
DE   AltName: Full=E3 ubiquitin-protein ligase MUL1;
DE   AltName: Full=Growth inhibition and death E3 ligase;
DE   AltName: Full=Mitochondrial-anchored protein ligase;
DE            Short=MAPL;
DE   AltName: Full=Putative NF-kappa-B-activating protein 266;
DE   AltName: Full=RING finger protein 218;
GN   Name=MUL1; Synonyms=C1orf166, GIDE, MAPL, MULAN, RNF218;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IDA:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; IMP:UniProtKB.
DR   GO; GO:0051646; P:mitochondrion localization; IMP:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0071650; P:negative regulation of chemokine (C-C motif) ligand 5 production; IMP:UniProtKB.
DR   GO; GO:0050689; P:negative regulation of defense response to virus by host; IMP:UniProtKB.
DR   GO; GO:0045824; P:negative regulation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0010637; P:negative regulation of mitochondrial fusion; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0060339; P:negative regulation of type I interferon-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0090141; P:positive regulation of mitochondrial fission; IDA:UniProtKB.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:1901028; P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IDA:UniProtKB.
//
ID   MUM1_HUMAN              Reviewed;         710 AA.
AC   Q2TAK8; A1L489; B5ME02; B7ZLY8; J3KQD6; Q13109; Q5XKB9; Q8N2I4;
AC   Q96A67;
DE   RecName: Full=PWWP domain-containing protein MUM1;
DE   AltName: Full=Mutated melanoma-associated antigen 1;
DE            Short=MUM-1;
DE   AltName: Full=Protein expandere;
GN   Name=MUM1; Synonyms=EXPAND1;
DR   GO; GO:0031491; F:nucleosome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
//
ID   MUML1_HUMAN             Reviewed;         696 AA.
AC   Q5H9M0; D3DUX2; Q49AS5; Q8N2C0; Q96MT6;
DE   RecName: Full=PWWP domain-containing protein MUM1L1;
DE   AltName: Full=Mutated melanoma-associated antigen 1-like protein 1;
DE            Short=MUM1-like protein 1;
GN   Name=MUM1L1;
//
ID   MURC_HUMAN              Reviewed;         364 AA.
AC   Q5BKX8; B1PRL3; B4DT88;
DE   RecName: Full=Muscle-related coiled-coil protein;
DE   AltName: Full=Muscle-restricted coiled-coil protein;
GN   Name=MURC;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MUS81_HUMAN             Reviewed;         551 AA.
AC   Q96NY9; Q9H7D9;
DE   RecName: Full=Crossover junction endonuclease MUS81;
DE            EC=3.1.22.-;
GN   Name=MUS81;
DR   GO; GO:0048257; F:3'-flap endonuclease activity; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IMP:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
//
ID   MUSC_HUMAN              Reviewed;         206 AA.
AC   O60682; O75946; Q53XZ2; Q9BRE7;
DE   RecName: Full=Musculin;
DE   AltName: Full=Activated B-cell factor 1;
DE            Short=ABF-1;
DE   AltName: Full=Class A basic helix-loop-helix protein 22;
DE            Short=bHLHa22;
GN   Name=MSC; Synonyms=ABF1, BHLHA22;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0014707; P:branchiomeric skeletal muscle development; IEA:Ensembl.
DR   GO; GO:0060539; P:diaphragm development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MUSK_HUMAN              Reviewed;         869 AA.
AC   O15146; Q32MJ8; Q32MJ9; Q5VZW7; Q5VZW8;
DE   RecName: Full=Muscle, skeletal receptor tyrosine-protein kinase;
DE            EC=2.7.10.1;
DE   AltName: Full=Muscle-specific tyrosine-protein kinase receptor;
DE            Short=MuSK;
DE            Short=Muscle-specific kinase receptor;
DE   Flags: Precursor;
GN   Name=MUSK;
DR   GuidetoPHARMACOLOGY; 1847; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007613; P:memory; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007528; P:neuromuscular junction development; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:GOC.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:2000541; P:positive regulation of protein geranylgeranylation; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0008582; P:regulation of synaptic growth at neuromuscular junction; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0071340; P:skeletal muscle acetylcholine-gated channel clustering; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   MUT7_HUMAN              Reviewed;         876 AA.
AC   Q8N9H8; B8A4U7; C9JIQ9; Q2TAK4; Q8N3X4; Q8NHD1; Q96NP1;
DE   RecName: Full=Exonuclease mut-7 homolog;
DE            EC=3.1.-.-;
DE   AltName: Full=Exonuclease 3'-5' domain-containing protein 3;
GN   Name=EXD3; ORFNames=HBE269;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   MUT7B_HUMAN             Reviewed;         252 AA.
AC   Q9NX53; Q6P1M1; Q8IXT8;
DE   RecName: Full=Exonuclease mut-7 homolog, isoform 5;
GN   Name=EXD3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MUTA_HUMAN              Reviewed;         750 AA.
AC   P22033; A8K953; Q5SYZ3; Q96B11; Q9UD64;
DE   RecName: Full=Methylmalonyl-CoA mutase, mitochondrial;
DE            Short=MCM;
DE            EC=5.4.99.2;
DE   AltName: Full=Methylmalonyl-CoA isomerase;
DE   Flags: Precursor;
GN   Name=MUT;
DR   GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004494; F:methylmalonyl-CoA mutase activity; TAS:ProtInc.
DR   GO; GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   MUTYH_HUMAN             Reviewed;         546 AA.
AC   Q9UIF7; D3DPZ4; Q15830; Q9UBP2; Q9UBS7; Q9UIF4; Q9UIF5; Q9UIF6;
DE   RecName: Full=A/G-specific adenine DNA glycosylase;
DE            EC=3.2.2.-;
DE   AltName: Full=MutY homolog;
DE            Short=hMYH;
GN   Name=MUTYH; Synonyms=MYH;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032407; F:MutSalpha complex binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0045007; P:depurination; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006298; P:mismatch repair; TAS:ProtInc.
//
ID   MVD1_HUMAN              Reviewed;         400 AA.
AC   P53602; Q53Y65;
DE   RecName: Full=Diphosphomevalonate decarboxylase;
DE            EC=4.1.1.33;
DE   AltName: Full=Mevalonate (diphospho)decarboxylase;
DE            Short=MDDase;
DE   AltName: Full=Mevalonate pyrophosphate decarboxylase;
GN   Name=MVD; Synonyms=MPD;
DR   GuidetoPHARMACOLOGY; 642; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004163; F:diphosphomevalonate decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0006489; P:dolichyl diphosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   MVP_HUMAN               Reviewed;         893 AA.
AC   Q14764; Q96BG4; Q9BPW6; Q9BQT1; Q9UBD1;
DE   RecName: Full=Major vault protein;
DE            Short=MVP;
DE   AltName: Full=Lung resistance-related protein;
GN   Name=MVP; Synonyms=LRP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0038127; P:ERBB signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0023057; P:negative regulation of signaling; IDA:UniProtKB.
DR   GO; GO:0072376; P:protein activation cascade; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   MX1_HUMAN               Reviewed;         662 AA.
AC   P20591; B2RDA5; B3KU10; C9IYV7; C9J8D6; C9JN19; C9JN88; C9JUL1;
AC   C9JZS6; D3DSI8; Q86YP5; Q96CI3;
DE   RecName: Full=Interferon-induced GTP-binding protein Mx1;
DE   AltName: Full=Interferon-induced protein p78;
DE            Short=IFI-78K;
DE   AltName: Full=Interferon-regulated resistance GTP-binding protein MxA;
DE   AltName: Full=Myxoma resistance protein 1;
DE   AltName: Full=Myxovirus resistance protein 1;
DE   Contains:
DE     RecName: Full=Interferon-induced GTP-binding protein Mx1, N-terminally processed;
GN   Name=MX1;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0034340; P:response to type I interferon; TAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   MX2_HUMAN               Reviewed;         715 AA.
AC   P20592; D3DSI7;
DE   RecName: Full=Interferon-induced GTP-binding protein Mx2;
DE   AltName: Full=Interferon-regulated resistance GTP-binding protein MxB;
DE   AltName: Full=Myxovirus resistance protein 2;
DE   AltName: Full=p78-related protein;
GN   Name=MX2;
DR   GO; GO:0005525; F:GTP binding; IMP:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IMP:UniProtKB.
DR   GO; GO:0035455; P:response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   MXI1_HUMAN              Reviewed;         228 AA.
AC   P50539; B1ANN7; D3DR25; D3DRA9; Q15887; Q6FHW2; Q96E53;
DE   RecName: Full=Max-interacting protein 1;
DE            Short=Max interactor 1;
DE   AltName: Full=Class C basic helix-loop-helix protein 11;
DE            Short=bHLHc11;
GN   Name=MXI1; Synonyms=BHLHC11;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MXRA5_HUMAN             Reviewed;        2828 AA.
AC   Q9NR99; Q6P1M7; Q9Y3Y8;
DE   RecName: Full=Matrix-remodeling-associated protein 5;
DE   AltName: Full=Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan;
DE            Short=Adlican;
DE   Flags: Precursor;
GN   Name=MXRA5;
//
ID   MXRA7_HUMAN             Reviewed;         204 AA.
AC   P84157; Q0P5W3;
DE   RecName: Full=Matrix-remodeling-associated protein 7;
DE   AltName: Full=Transmembrane anchor protein 1;
GN   Name=MXRA7; Synonyms=TMAP1;
//
ID   MXRA8_HUMAN             Reviewed;         442 AA.
AC   Q9BRK3; B3KTR6; B4DE34; Q5TA39; Q96KC3;
DE   RecName: Full=Matrix-remodeling-associated protein 8;
DE   AltName: Full=Limitrin;
DE   Flags: Precursor;
GN   Name=MXRA8;
DR   GO; GO:0060857; P:establishment of glial blood-brain barrier; ISS:UniProt.
//
ID   MY15B_HUMAN             Reviewed;        1530 AA.
AC   Q96JP2;
DE   RecName: Full=Unconventional myosin-XVB;
DE   AltName: Full=Myosin XVBP;
DE   AltName: Full=Unconventional myosin-15B;
GN   Name=MYO15B; Synonyms=KIAA1783, MYO15BP;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MY18A_HUMAN             Reviewed;        2054 AA.
AC   Q92614; Q5H9U3; Q5W9F9; Q5W9G1; Q8IXP8;
DE   RecName: Full=Unconventional myosin-XVIIIa;
DE   AltName: Full=Molecule associated with JAK3 N-terminus;
DE            Short=MAJN;
DE   AltName: Full=Myosin containing a PDZ domain;
GN   Name=MYO18A; Synonyms=KIAA0216, MYSPDZ;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0043531; F:ADP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0006259; P:DNA metabolic process; IEA:InterPro.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0048194; P:Golgi vesicle budding; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
//
ID   MY18B_HUMAN             Reviewed;        2567 AA.
AC   Q8IUG5; B2RWP3; F5GYU7; Q8NDI8; Q8TE65; Q8WWS0; Q96KH2; Q96KR8;
AC   Q96KR9;
DE   RecName: Full=Unconventional myosin-XVIIIb;
GN   Name=MYO18B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYADM_HUMAN             Reviewed;         322 AA.
AC   Q96S97; B2RE58; Q542Z1; Q7Z507; Q8N9R4; Q96CS6; Q96SK9;
DE   RecName: Full=Myeloid-associated differentiation marker;
DE   AltName: Full=Protein SB135;
GN   Name=MYADM; ORFNames=UNQ553/PRO1110;
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProt.
DR   GO; GO:0031579; P:membrane raft organization; IMP:UniProt.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IMP:UniProt.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProt.
DR   GO; GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:UniProt.
DR   GO; GO:0090038; P:negative regulation of protein kinase C signaling; IMP:UniProt.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProt.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProt.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IMP:UniProt.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:UniProt.
//
ID   MYBA_HUMAN              Reviewed;         752 AA.
AC   P10243; E7EW29; Q495F9;
DE   RecName: Full=Myb-related protein A;
DE            Short=A-Myb;
DE   AltName: Full=Myb-like protein 1;
GN   Name=MYBL1; Synonyms=AMYB;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYBB_HUMAN              Reviewed;         700 AA.
AC   P10244; B2RBS5; B7Z8D9; F8W6N6; Q53F07;
DE   RecName: Full=Myb-related protein B;
DE            Short=B-Myb;
DE   AltName: Full=Myb-like protein 2;
GN   Name=MYBL2; Synonyms=BMYB;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYBPH_HUMAN             Reviewed;         477 AA.
AC   Q13203; Q16886; Q86YC5;
DE   RecName: Full=Myosin-binding protein H;
DE            Short=MyBP-H;
DE   AltName: Full=H-protein;
GN   Name=MYBPH;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; TAS:ProtInc.
//
ID   MYBPP_HUMAN             Reviewed;         947 AA.
AC   Q8TBZ2; A6NHJ3; Q8TDV8; Q9H0K0;
DE   RecName: Full=MYCBP-associated protein;
DE   AltName: Full=AMAM-1;
DE   AltName: Full=AMY-1-binding protein 1;
DE            Short=AMAP-1;
GN   Name=MYCBPAP; Synonyms=AMAP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; ISS:UniProtKB.
//
ID   MYB_HUMAN               Reviewed;         640 AA.
AC   P10242; E9PI07; E9PLZ5; E9PNA4; E9PNL6; E9PRS2; P78391; P78392;
AC   P78525; P78526; Q14023; Q14024; Q708E4; Q708E7; Q9UE83;
DE   RecName: Full=Transcriptional activator Myb;
DE   AltName: Full=Proto-oncogene c-Myb;
GN   Name=MYB;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IMP:UniProtKB.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0051574; P:positive regulation of histone H3-K9 methylation; IMP:UniProtKB.
DR   GO; GO:0045624; P:positive regulation of T-helper cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYCB2_HUMAN             Reviewed;        4640 AA.
AC   O75592; A6NJC6; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4;
DE   RecName: Full=E3 ubiquitin-protein ligase MYCBP2;
DE            EC=6.3.2.-;
DE   AltName: Full=Myc-binding protein 2;
DE   AltName: Full=Pam/highwire/rpm-1 protein;
DE   AltName: Full=Protein associated with Myc;
GN   Name=MYCBP2; Synonyms=KIAA0916, PAM;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0021785; P:branchiomotor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYCBP_HUMAN             Reviewed;         103 AA.
AC   Q99417; B2R4N0; Q5TA64; Q96HE2;
DE   RecName: Full=C-Myc-binding protein;
DE   AltName: Full=Associate of Myc 1;
DE            Short=AMY-1;
GN   Name=MYCBP; Synonyms=AMY1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYCD_HUMAN              Reviewed;         938 AA.
AC   Q8IZQ8; Q5UBU5; Q8N7Q1;
DE   RecName: Full=Myocardin;
GN   Name=MYOCD; Synonyms=MYCD;
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IDA:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0035051; P:cardiocyte differentiation; NAS:UniProtKB.
DR   GO; GO:1900222; P:negative regulation of beta-amyloid clearance; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:2001015; P:negative regulation of skeletal muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:2000727; P:positive regulation of cardiac muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:2000724; P:positive regulation of cardiac vascular smooth muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0051152; P:positive regulation of smooth muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0003257; P:positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; IDA:BHF-UCL.
DR   GO; GO:2000721; P:positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035065; P:regulation of histone acetylation; ISS:UniProtKB.
DR   GO; GO:0051150; P:regulation of smooth muscle cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEP:BHF-UCL.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
//
ID   MYCL_HUMAN              Reviewed;         364 AA.
AC   P12524; A2A2C9; B4DJH2; Q14897; Q5QPL0; Q5QPL1; Q9NUE9;
DE   RecName: Full=Protein L-Myc;
DE   AltName: Full=Class E basic helix-loop-helix protein 38;
DE            Short=bHLHe38;
DE   AltName: Full=Protein L-Myc-1;
DE   AltName: Full=V-myc myelocytomatosis viral oncogene homolog;
GN   Name=MYCL; Synonyms=BHLHE38, LMYC, MYCL1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   MYCN_HUMAN              Reviewed;         464 AA.
AC   P04198; Q53XS5; Q6LDT9;
DE   RecName: Full=N-myc proto-oncogene protein;
DE   AltName: Full=Class E basic helix-loop-helix protein 37;
DE            Short=bHLHe37;
GN   Name=MYCN; Synonyms=BHLHE37, NMYC;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   MYCP1_HUMAN             Reviewed;         358 AA.
AC   P12525; O43372;
DE   RecName: Full=Putative myc-like protein MYCLP1;
DE   AltName: Full=Protein L-Myc-2;
DE   AltName: Full=V-myc myelocytomatosis viral oncogene homolog pseudogene 1;
GN   Name=MYCLP1; Synonyms=MYCL1P1, MYCL2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
//
ID   MYCT1_HUMAN             Reviewed;         235 AA.
AC   Q8N699; Q8N396; Q8TBE8; Q9H763;
DE   RecName: Full=Myc target protein 1;
DE   AltName: Full=Myc target in myeloid cells protein 1;
GN   Name=MYCT1; Synonyms=MTLC, MTMC1;
//
ID   MYCPP_HUMAN             Reviewed;        1863 AA.
AC   Q7Z401; E7EPL3; Q14655; Q86T77; Q8IVX2; Q8NB93;
DE   RecName: Full=C-myc promoter-binding protein;
DE   AltName: Full=DENN domain-containing protein 4A;
GN   Name=DENND4A; Synonyms=IRLB, MYCPBP;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYCT_HUMAN              Reviewed;         648 AA.
AC   Q96QE2; Q17S07;
DE   RecName: Full=Proton myo-inositol cotransporter;
DE            Short=H(+)-myo-inositol cotransporter;
DE            Short=Hmit;
DE   AltName: Full=H(+)-myo-inositol symporter;
DE   AltName: Full=Solute carrier family 2 member 13;
GN   Name=SLC2A13;
DR   GO; GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   MYC_HUMAN               Reviewed;         439 AA.
AC   P01106; A8WFE7; P01107; Q14026;
DE   RecName: Full=Myc proto-oncogene protein;
DE   AltName: Full=Class E basic helix-loop-helix protein 39;
DE            Short=bHLHe39;
DE   AltName: Full=Proto-oncogene c-Myc;
DE   AltName: Full=Transcription factor p64;
GN   Name=MYC; Synonyms=BHLHE39;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IEP:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; IDA:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; NAS:UniProtKB.
DR   GO; GO:0044346; P:fibroblast apoptotic process; TAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0051782; P:negative regulation of cell division; IDA:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0045656; P:negative regulation of monocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0032873; P:negative regulation of stress-activated MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0015671; P:oxygen transport; NAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:0090096; P:positive regulation of metanephric cap mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:MGI.
DR   GO; GO:0032204; P:regulation of telomere maintenance; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEP:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0070848; P:response to growth factor; TAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   MYD88_HUMAN             Reviewed;         296 AA.
AC   Q99836; B4DKH8; B4DKU4; B4DQ60; B4DQ72; J3KPU4; J3KQ87; J3KQJ6;
AC   P78397; Q53XS7;
DE   RecName: Full=Myeloid differentiation primary response protein MyD88;
GN   Name=MYD88;
DR   GO; GO:0005123; F:death receptor binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070976; F:TIR domain binding; IPI:BHF-UCL.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:BHF-UCL.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; ISS:BHF-UCL.
DR   GO; GO:0032747; P:positive regulation of interleukin-23 production; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; ISS:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   MYEF2_HUMAN             Reviewed;         600 AA.
AC   Q9P2K5; A7MCZ9; C9J921; C9K0J4; Q6NUM5; Q7L388; Q7Z4B7; Q9H922;
AC   Q9NUQ1;
DE   RecName: Full=Myelin expression factor 2;
DE            Short=MEF-2;
DE            Short=MyEF-2;
DE   AltName: Full=MST156;
GN   Name=MYEF2; Synonyms=KIAA1341;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0014902; P:myotube differentiation; IEP:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IEP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYF5_HUMAN              Reviewed;         255 AA.
AC   P13349; Q6ISR9;
DE   RecName: Full=Myogenic factor 5;
DE            Short=Myf-5;
DE   AltName: Full=Class C basic helix-loop-helix protein 2;
DE            Short=bHLHc2;
GN   Name=MYF5; Synonyms=BHLHC2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0042693; P:muscle cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0060415; P:muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:ProtInc.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
//
ID   MYEOV_HUMAN             Reviewed;         313 AA.
AC   Q96EZ4; Q9UGN6; Q9UGN7;
DE   RecName: Full=Myeloma-overexpressed gene protein;
DE   AltName: Full=Oncogene in multiple myeloma;
GN   Name=MYEOV; Synonyms=OCIM;
//
ID   MYG1_HUMAN              Reviewed;         376 AA.
AC   Q9HB07;
DE   RecName: Full=UPF0160 protein MYG1, mitochondrial;
DE   Flags: Precursor;
GN   Name=C12orf10;
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; NAS:UniProtKB.
//
ID   MYF6_HUMAN              Reviewed;         242 AA.
AC   P23409; B2R898; Q53X80; Q6FHI9;
DE   RecName: Full=Myogenic factor 6;
DE            Short=Myf-6;
DE   AltName: Full=Class C basic helix-loop-helix protein 4;
DE            Short=bHLHc4;
DE   AltName: Full=Muscle-specific regulatory factor 4;
GN   Name=MYF6; Synonyms=BHLHC4, MRF4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0042693; P:muscle cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0060415; P:muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:ProtInc.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   MYG_HUMAN               Reviewed;         154 AA.
AC   P02144; Q52H51; Q5THY7;
DE   RecName: Full=Myoglobin;
GN   Name=MB;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:Ensembl.
DR   GO; GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0031444; P:slow-twitch skeletal muscle fiber contraction; IEA:Ensembl.
//
ID   MYH10_HUMAN             Reviewed;        1976 AA.
AC   P35580; F8VTL3; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16;
DE   RecName: Full=Myosin-10;
DE   AltName: Full=Cellular myosin heavy chain, type B;
DE   AltName: Full=Myosin heavy chain 10;
DE   AltName: Full=Myosin heavy chain, non-muscle IIb;
DE   AltName: Full=Non-muscle myosin heavy chain B;
DE            Short=NMMHC-B;
DE   AltName: Full=Non-muscle myosin heavy chain IIb;
DE            Short=NMMHC II-b;
DE            Short=NMMHC-IIB;
GN   Name=MYH10;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IDA:MGI.
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IDA:MGI.
DR   GO; GO:0043531; F:ADP binding; IDA:MGI.
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; IDA:MGI.
DR   GO; GO:0031032; P:actomyosin structure organization; IMP:UniProt.
DR   GO; GO:0007512; P:adult heart development; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:UniProt.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0055003; P:cardiac myofibril assembly; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0021592; P:fourth ventricle development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0021670; P:lateral ventricle development; IEA:Ensembl.
DR   GO; GO:0000281; P:mitotic cytokinesis; IDA:MGI.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007097; P:nuclear migration; IEA:Ensembl.
DR   GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0006930; P:substrate-dependent cell migration, cell extension; IEA:Ensembl.
DR   GO; GO:0021678; P:third ventricle development; IEA:Ensembl.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
//
ID   MYH13_HUMAN             Reviewed;        1938 AA.
AC   Q9UKX3; O95252; Q9P0U8;
DE   RecName: Full=Myosin-13;
DE   AltName: Full=Myosin heavy chain 13;
DE   AltName: Full=Myosin heavy chain, skeletal muscle, extraocular;
DE            Short=MyHC-EO;
DE   AltName: Full=Myosin heavy chain, skeletal muscle, laryngeal;
DE            Short=MyHC-IIL;
DE   AltName: Full=Superfast myosin;
GN   Name=MYH13;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; TAS:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0006936; P:muscle contraction; TAS:UniProtKB.
//
ID   MYH11_HUMAN             Reviewed;        1972 AA.
AC   P35749; D2JYH7; O00396; O94944; P78422; Q3MIV8; Q3MNF0; Q3MNF1;
DE   RecName: Full=Myosin-11;
DE   AltName: Full=Myosin heavy chain 11;
DE   AltName: Full=Myosin heavy chain, smooth muscle isoform;
DE   AltName: Full=SMMHC;
GN   Name=MYH11; Synonyms=KIAA0866;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0048739; P:cardiac muscle fiber development; IMP:UniProtKB.
DR   GO; GO:0048251; P:elastic fiber assembly; IMP:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030241; P:skeletal muscle myosin thick filament assembly; ISS:UniProtKB.
DR   GO; GO:0006939; P:smooth muscle contraction; ISS:UniProtKB.
//
ID   MYH14_HUMAN             Reviewed;        1995 AA.
AC   Q7Z406; B0I1S2; C3TTN4; Q5CZ75; Q6XYE4; Q76B62; Q8WV23; Q96I22;
AC   Q9BT27; Q9BW35; Q9H882;
DE   RecName: Full=Myosin-14;
DE   AltName: Full=Myosin heavy chain 14;
DE   AltName: Full=Myosin heavy chain, non-muscle IIc;
DE   AltName: Full=Non-muscle myosin heavy chain IIc;
DE            Short=NMHC II-C;
GN   Name=MYH14; Synonyms=KIAA2034; ORFNames=FP17425;
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; IEA:Ensembl.
DR   GO; GO:0030048; P:actin filament-based movement; IEA:Ensembl.
DR   GO; GO:0031032; P:actomyosin structure organization; IDA:UniProt.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProt.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:UniProt.
DR   GO; GO:0019228; P:neuronal action potential; IMP:UniProt.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProt.
DR   GO; GO:0014732; P:skeletal muscle atrophy; IMP:UniProt.
DR   GO; GO:0003009; P:skeletal muscle contraction; IMP:UniProt.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IMP:UniProt.
DR   GO; GO:0071625; P:vocalization behavior; IMP:UniProt.
//
ID   MYH15_HUMAN             Reviewed;        1946 AA.
AC   Q9Y2K3;
DE   RecName: Full=Myosin-15;
DE   AltName: Full=Myosin heavy chain 15;
GN   Name=MYH15; Synonyms=KIAA1000;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYH1_HUMAN              Reviewed;        1939 AA.
AC   P12882; Q14CA4; Q9Y622;
DE   RecName: Full=Myosin-1;
DE   AltName: Full=Myosin heavy chain 1;
DE   AltName: Full=Myosin heavy chain 2x;
DE            Short=MyHC-2x;
DE   AltName: Full=Myosin heavy chain IIx/d;
DE            Short=MyHC-IIx/d;
DE   AltName: Full=Myosin heavy chain, skeletal muscle, adult 1;
GN   Name=MYH1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
//
ID   MYH2_HUMAN              Reviewed;        1941 AA.
AC   Q9UKX2; A0AVL4; Q14322; Q16229; Q86T56;
DE   RecName: Full=Myosin-2;
DE   AltName: Full=Myosin heavy chain 2;
DE   AltName: Full=Myosin heavy chain 2a;
DE            Short=MyHC-2a;
DE   AltName: Full=Myosin heavy chain IIa;
DE            Short=MyHC-IIa;
DE   AltName: Full=Myosin heavy chain, skeletal muscle, adult 2;
GN   Name=MYH2; Synonyms=MYHSA2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0006936; P:muscle contraction; TAS:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; NAS:BHF-UCL.
DR   GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
//
ID   MYH3_HUMAN              Reviewed;        1940 AA.
AC   P11055; Q15492;
DE   RecName: Full=Myosin-3;
DE   AltName: Full=Muscle embryonic myosin heavy chain;
DE   AltName: Full=Myosin heavy chain 3;
DE   AltName: Full=Myosin heavy chain, fast skeletal muscle, embryonic;
DE   AltName: Full=SMHCE;
GN   Name=MYH3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042623; F:ATPase activity, coupled; NAS:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; NAS:BHF-UCL.
DR   GO; GO:0000146; F:microfilament motor activity; NAS:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:BHF-UCL.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IC:BHF-UCL.
DR   GO; GO:0060325; P:face morphogenesis; IC:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0045214; P:sarcomere organization; NAS:BHF-UCL.
DR   GO; GO:0003009; P:skeletal muscle contraction; IMP:BHF-UCL.
//
ID   MYH4_HUMAN              Reviewed;        1939 AA.
AC   Q9Y623;
DE   RecName: Full=Myosin-4;
DE   AltName: Full=Myosin heavy chain 2b;
DE            Short=MyHC-2b;
DE   AltName: Full=Myosin heavy chain 4;
DE   AltName: Full=Myosin heavy chain IIb;
DE            Short=MyHC-IIb;
DE   AltName: Full=Myosin heavy chain, skeletal muscle, fetal;
GN   Name=MYH4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0000146; F:microfilament motor activity; NAS:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:BHF-UCL.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; NAS:BHF-UCL.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
//
ID   MYH7B_HUMAN             Reviewed;        1941 AA.
AC   A7E2Y1; Q5JVW7; Q6NT44; Q6NT57; Q6WG75; Q96I57; Q9NWE2; Q9P216;
DE   RecName: Full=Myosin-7B;
DE   AltName: Full=Antigen MLAA-21;
DE   AltName: Full=Myosin cardiac muscle beta chain;
DE   AltName: Full=Myosin heavy chain 7B, cardiac muscle beta isoform;
DE   AltName: Full=Slow A MYH14;
GN   Name=MYH7B; Synonyms=KIAA1512;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   MYH6_HUMAN              Reviewed;        1939 AA.
AC   P13533; A2RTX1; D9YZU2; Q13943; Q14906; Q14907;
DE   RecName: Full=Myosin-6;
DE   AltName: Full=Myosin heavy chain 6;
DE   AltName: Full=Myosin heavy chain, cardiac muscle alpha isoform;
DE            Short=MyHC-alpha;
GN   Name=MYH6; Synonyms=MYHCA;
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IMP:HGNC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:HGNC.
DR   GO; GO:0000146; F:microfilament motor activity; IDA:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0007512; P:adult heart development; IMP:HGNC.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:BHF-UCL.
DR   GO; GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IMP:HGNC.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0048739; P:cardiac muscle fiber development; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; IDA:HGNC.
DR   GO; GO:0030049; P:muscle filament sliding; IMP:HGNC.
DR   GO; GO:0030239; P:myofibril assembly; ISS:BHF-UCL.
DR   GO; GO:0043462; P:regulation of ATPase activity; ISS:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0060420; P:regulation of heart growth; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IDA:HGNC.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IDA:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; ISS:BHF-UCL.
DR   GO; GO:0006941; P:striated muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:HGNC.
DR   GO; GO:0007522; P:visceral muscle development; ISS:BHF-UCL.
//
ID   MYH7_HUMAN              Reviewed;        1935 AA.
AC   P12883; A2TDB6; B6D424; Q14836; Q14837; Q14904; Q16579; Q2M1Y6;
AC   Q92679; Q9H1D5; Q9UDA2; Q9UMM8;
DE   RecName: Full=Myosin-7;
DE   AltName: Full=Myosin heavy chain 7;
DE   AltName: Full=Myosin heavy chain slow isoform;
DE            Short=MyHC-slow;
DE   AltName: Full=Myosin heavy chain, cardiac muscle beta isoform;
DE            Short=MyHC-beta;
GN   Name=MYH7; Synonyms=MYHCB;
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IMP:HGNC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:HGNC.
DR   GO; GO:0000146; F:microfilament motor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0007512; P:adult heart development; IMP:HGNC.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; IDA:HGNC.
DR   GO; GO:0030049; P:muscle filament sliding; IMP:HGNC.
DR   GO; GO:0002027; P:regulation of heart rate; IDA:HGNC.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IDA:BHF-UCL.
DR   GO; GO:0006941; P:striated muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   MYH8_HUMAN              Reviewed;        1937 AA.
AC   P13535; Q14910;
DE   RecName: Full=Myosin-8;
DE   AltName: Full=Myosin heavy chain 8;
DE   AltName: Full=Myosin heavy chain, skeletal muscle, perinatal;
DE            Short=MyHC-perinatal;
GN   Name=MYH8;
DR   GO; GO:0051015; F:actin filament binding; TAS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IMP:BHF-UCL.
DR   GO; GO:0016887; F:ATPase activity; IMP:BHF-UCL.
DR   GO; GO:0000146; F:microfilament motor activity; IMP:BHF-UCL.
DR   GO; GO:0032027; F:myosin light chain binding; TAS:BHF-UCL.
DR   GO; GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; NAS:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; IMP:BHF-UCL.
DR   GO; GO:0003009; P:skeletal muscle contraction; IMP:BHF-UCL.
//
ID   MYH9_HUMAN              Reviewed;        1960 AA.
AC   P35579; A8K6E4; O60805; Q60FE2; Q86T83;
DE   RecName: Full=Myosin-9;
DE   AltName: Full=Cellular myosin heavy chain, type A;
DE   AltName: Full=Myosin heavy chain 9;
DE   AltName: Full=Myosin heavy chain, non-muscle IIa;
DE   AltName: Full=Non-muscle myosin heavy chain A;
DE            Short=NMMHC-A;
DE   AltName: Full=Non-muscle myosin heavy chain IIa;
DE            Short=NMMHC II-a;
DE            Short=NMMHC-IIA;
GN   Name=MYH9;
DR   GO; GO:0003779; F:actin binding; IDA:MGI.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IDA:MGI.
DR   GO; GO:0043531; F:ADP binding; IDA:MGI.
DR   GO; GO:0005524; F:ATP binding; IDA:MGI.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; IDA:UniProtKB.
DR   GO; GO:0003774; F:motor activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043495; F:protein anchor; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; IDA:UniProtKB.
DR   GO; GO:0031032; P:actomyosin structure organization; IDA:UniProt.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProt.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0051295; P:establishment of meiotic spindle localization; IEA:Ensembl.
DR   GO; GO:0001768; P:establishment of T cell polarity; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; NAS:UniProtKB.
DR   GO; GO:0000212; P:meiotic spindle organization; IEA:Ensembl.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0030220; P:platelet formation; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0032796; P:uropod organization; IEA:Ensembl.
//
ID   MYL10_HUMAN             Reviewed;         226 AA.
AC   Q9BUA6;
DE   RecName: Full=Myosin regulatory light chain 10;
DE   AltName: Full=Myosin light chain 2, lymphocyte-specific;
DE   AltName: Full=Precursor lymphocyte-specific regulatory light chain;
GN   Name=MYL10; Synonyms=MYLC2PL, PLRLC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   MYL1_HUMAN              Reviewed;         194 AA.
AC   P05976; B2R4N6; B2R4T6; P06741; Q6IBD5;
DE   RecName: Full=Myosin light chain 1/3, skeletal muscle isoform;
DE            Short=MLC1/MLC3;
DE            Short=MLC1F/MLC3F;
DE   AltName: Full=Myosin light chain alkali 1/2;
DE            Short=Myosin light chain A1/A2;
GN   Name=MYL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; NAS:BHF-UCL.
//
ID   MYL3_HUMAN              Reviewed;         195 AA.
AC   P08590; B2R534; Q9NRS8;
DE   RecName: Full=Myosin light chain 3;
DE   AltName: Full=Cardiac myosin light chain 1;
DE            Short=CMLC1;
DE   AltName: Full=Myosin light chain 1, slow-twitch muscle B/ventricular isoform;
DE            Short=MLC1SB;
DE   AltName: Full=Ventricular/slow twitch myosin alkali light chain;
GN   Name=MYL3;
DR   GO; GO:0003785; F:actin monomer binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; IEA:Ensembl.
DR   GO; GO:0032038; F:myosin II heavy chain binding; NAS:BHF-UCL.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; ISS:BHF-UCL.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IMP:BHF-UCL.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   MYL4_HUMAN              Reviewed;         197 AA.
AC   P12829; D3DXJ7; P11783;
DE   RecName: Full=Myosin light chain 4;
DE   AltName: Full=Myosin light chain 1, embryonic muscle/atrial isoform;
DE   AltName: Full=Myosin light chain alkali GT-1 isoform;
GN   Name=MYL4; Synonyms=MLC1; ORFNames=PRO1957;
DR   GO; GO:0051015; F:actin filament binding; IMP:BHF-UCL.
DR   GO; GO:0003785; F:actin monomer binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0032038; F:myosin II heavy chain binding; NAS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IMP:BHF-UCL.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IMP:BHF-UCL.
//
ID   MYL5_HUMAN              Reviewed;         173 AA.
AC   Q02045; Q8IXL8;
DE   RecName: Full=Myosin light chain 5;
DE   AltName: Full=Myosin regulatory light chain 5;
DE   AltName: Full=Superfast myosin regulatory light chain 2;
DE            Short=MYLC2;
DE            Short=MyLC-2;
GN   Name=MYL5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.
//
ID   MYL6B_HUMAN             Reviewed;         208 AA.
AC   P14649;
DE   RecName: Full=Myosin light chain 6B;
DE   AltName: Full=Myosin light chain 1 slow-twitch muscle A isoform;
DE            Short=MLC1sa;
DE   AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6B;
GN   Name=MYL6B; Synonyms=MLC1SA;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:HGNC.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0006936; P:muscle contraction; TAS:HGNC.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:HGNC.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:HGNC.
//
ID   MYL9_HUMAN              Reviewed;         172 AA.
AC   P24844; E1P5T6; Q9BQL9; Q9BUF9; Q9H136;
DE   RecName: Full=Myosin regulatory light polypeptide 9;
DE   AltName: Full=20 kDa myosin light chain;
DE            Short=LC20;
DE   AltName: Full=MLC-2C;
DE   AltName: Full=Myosin RLC;
DE   AltName: Full=Myosin regulatory light chain 2, smooth muscle isoform;
DE   AltName: Full=Myosin regulatory light chain 9;
DE   AltName: Full=Myosin regulatory light chain MRLC1;
GN   Name=MYL9; Synonyms=MLC2, MRLC1, MYRL2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.
//
ID   MYL6_HUMAN              Reviewed;         151 AA.
AC   P60660; P16475; P24572; P24573; Q12790; Q561V9; Q6IAZ0; Q6IPY5;
DE   RecName: Full=Myosin light polypeptide 6;
DE   AltName: Full=17 kDa myosin light chain;
DE            Short=LC17;
DE   AltName: Full=Myosin light chain 3;
DE            Short=MLC-3;
DE   AltName: Full=Myosin light chain alkali 3;
DE            Short=Myosin light chain A3;
DE   AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6;
GN   Name=MYL6;
DR   GO; GO:0030898; F:actin-dependent ATPase activity; ISS:HGNC.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003774; F:motor activity; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; IDA:HGNC.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0006936; P:muscle contraction; TAS:HGNC.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:HGNC.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:UniProtKB.
//
ID   MYLIP_HUMAN             Reviewed;         445 AA.
AC   Q8WY64; Q5TIA4; Q9BU73; Q9NRL9; Q9UHE7;
DE   RecName: Full=E3 ubiquitin-protein ligase MYLIP;
DE            EC=6.3.2.-;
DE   AltName: Full=Inducible degrader of the LDL-receptor;
DE            Short=Idol;
DE   AltName: Full=Myosin regulatory light chain interacting protein;
DE            Short=MIR;
GN   Name=MYLIP; Synonyms=BZF1, IDOL; ORFNames=BM-023, PP5242;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006928; P:cellular component movement; IMP:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0031648; P:protein destabilization; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0032803; P:regulation of low-density lipoprotein particle receptor catabolic process; IEA:Ensembl.
//
ID   MYLK2_HUMAN             Reviewed;         596 AA.
AC   Q9H1R3; Q569L1; Q96I84;
DE   RecName: Full=Myosin light chain kinase 2, skeletal/cardiac muscle;
DE            Short=MLCK2;
DE            EC=2.7.11.18;
GN   Name=MYLK2;
DR   GuidetoPHARMACOLOGY; 1553; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; ISS:BHF-UCL.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0004687; F:myosin light chain kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060048; P:cardiac muscle contraction; IC:BHF-UCL.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0032971; P:regulation of muscle filament sliding; IDA:BHF-UCL.
DR   GO; GO:0014816; P:satellite cell differentiation; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0006941; P:striated muscle contraction; IDA:BHF-UCL.
//
ID   MYLK3_HUMAN             Reviewed;         819 AA.
AC   Q32MK0; B5BUL9; B7Z5U8; Q32MK1; Q96DV1;
DE   RecName: Full=Myosin light chain kinase 3;
DE            EC=2.7.11.18;
DE   AltName: Full=Cardiac-MyBP-C-associated Ca/CaM kinase;
DE            Short=Cardiac-MLCK;
GN   Name=MYLK3; Synonyms=MLCK;
DR   GuidetoPHARMACOLOGY; 2110; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0004687; F:myosin light chain kinase activity; ISS:BHF-UCL.
DR   GO; GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0060298; P:positive regulation of sarcomere organization; ISS:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0002528; P:regulation of vascular permeability involved in acute inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; ISS:BHF-UCL.
DR   GO; GO:0048769; P:sarcomerogenesis; ISS:BHF-UCL.
//
ID   MYLK4_HUMAN             Reviewed;         388 AA.
AC   Q86YV6; A2RUC0; Q5TAW2;
DE   RecName: Full=Myosin light chain kinase family member 4;
DE            EC=2.7.11.1;
DE   AltName: Full=Sugen kinase 85;
DE            Short=SgK085;
GN   Name=MYLK4; Synonyms=SGK085;
DR   GuidetoPHARMACOLOGY; 2111; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   MYLK_HUMAN              Reviewed;        1914 AA.
AC   Q15746; B4DUE3; D3DN97; O95796; O95797; O95798; O95799; Q14844;
AC   Q16794; Q17S15; Q3ZCP9; Q5MY99; Q5MYA0; Q6P2N0; Q7Z4J0; Q9C0L5;
AC   Q9UBG5; Q9UBY6; Q9UIT9;
DE   RecName: Full=Myosin light chain kinase, smooth muscle;
DE            Short=MLCK;
DE            Short=smMLCK;
DE            EC=2.7.11.18;
DE   AltName: Full=Kinase-related protein;
DE            Short=KRP;
DE   AltName: Full=Telokin;
DE   Contains:
DE     RecName: Full=Myosin light chain kinase, smooth muscle, deglutamylated form;
GN   Name=MYLK; Synonyms=MLCK, MLCK1, MYLK1;
DR   GuidetoPHARMACOLOGY; 1552; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004687; F:myosin light chain kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007015; P:actin filament organization; IBA:RefGenome.
DR   GO; GO:0060414; P:aorta smooth muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0032060; P:bleb assembly; IMP:UniProtKB.
DR   GO; GO:0071476; P:cellular hypotonic response; IDA:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0090303; P:positive regulation of wound healing; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0006939; P:smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0014820; P:tonic smooth muscle contraction; ISS:UniProtKB.
//
ID   MYNN_HUMAN              Reviewed;         610 AA.
AC   Q9NPC7; B2R6C9; Q6QHA6; Q6QHA7; Q6R3G1; Q6R3G2; Q6R4A0; Q7Z716;
AC   Q7Z717; Q86Z11; Q86Z12; Q9NS01; Q9UIW8;
DE   RecName: Full=Myoneurin;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 31;
GN   Name=MYNN; Synonyms=OSZF, ZBTB31; ORFNames=SBBIZ1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   MYO10_HUMAN             Reviewed;        2058 AA.
AC   Q9HD67; A7E2D1; O94893; Q9NYM7; Q9P110; Q9P111; Q9UHF6;
DE   RecName: Full=Unconventional myosin-X;
DE   AltName: Full=Unconventional myosin-10;
GN   Name=MYO10; Synonyms=KIAA0799;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0030898; F:actin-dependent ATPase activity; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0060002; F:plus-end directed microfilament motor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; ISS:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; IMP:UniProtKB.
//
ID   MYO15_HUMAN             Reviewed;        3530 AA.
AC   Q9UKN7;
DE   RecName: Full=Unconventional myosin-XV;
DE   AltName: Full=Unconventional myosin-15;
GN   Name=MYO15A; Synonyms=MYO15;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   MYO16_HUMAN             Reviewed;        1858 AA.
AC   Q9Y6X6; A6H8Y0; A8MTX3; Q5VYX4; Q5VYX5; Q5VYX6; Q6ZS13; Q8N3C2;
AC   Q8N948;
DE   RecName: Full=Unconventional myosin-XVI;
DE   AltName: Full=Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3;
DE   AltName: Full=Unconventional myosin-16;
GN   Name=MYO16; Synonyms=KIAA0865, MYO16B, NYAP3;
DR   GO; GO:0051015; F:actin filament binding; ISS:HGNC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0021549; P:cerebellum development; ISS:HGNC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:BHF-UCL.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
//
ID   MYO19_HUMAN             Reviewed;         970 AA.
AC   Q96H55; Q59GS4; Q9H5X2;
DE   RecName: Full=Unconventional myosin-XIX;
DE   AltName: Full=Myosin head domain-containing protein 1;
GN   Name=MYO19; Synonyms=MYOHD1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYO1A_HUMAN             Reviewed;        1043 AA.
AC   Q9UBC5; Q9UQD7;
DE   RecName: Full=Unconventional myosin-Ia;
DE   AltName: Full=Brush border myosin I;
DE            Short=BBM-I;
DE            Short=BBMI;
DE   AltName: Full=Myosin I heavy chain;
DE            Short=MIHC;
GN   Name=MYO1A; Synonyms=MYHL;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0030033; P:microvillus assembly; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0051648; P:vesicle localization; IMP:UniProtKB.
//
ID   MYO1B_HUMAN             Reviewed;        1136 AA.
AC   O43795; O43794; Q7Z6L5;
DE   RecName: Full=Unconventional myosin-Ib;
DE   AltName: Full=MYH-1c;
DE   AltName: Full=Myosin I alpha;
DE            Short=MMI-alpha;
DE            Short=MMIa;
GN   Name=MYO1B;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; ISS:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; ISS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
//
ID   MYO1C_HUMAN             Reviewed;        1063 AA.
AC   O00159; Q4LE56; Q6NVJ7; Q86Y95;
DE   RecName: Full=Unconventional myosin-Ic;
DE   AltName: Full=Myosin I beta;
DE            Short=MMI-beta;
DE            Short=MMIb;
GN   Name=MYO1C;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0038089; P:positive regulation of cell migration by vascular endothelial growth factor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:1900748; P:positive regulation of vascular endothelial growth factor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IDA:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB.
//
ID   MYO1D_HUMAN             Reviewed;        1006 AA.
AC   O94832; A6H8V3; Q8NHP9;
DE   RecName: Full=Unconventional myosin-Id;
GN   Name=MYO1D; Synonyms=KIAA0727;
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; IEA:Ensembl.
DR   GO; GO:0061502; P:early endosome to recycling endosome transport; ISS:UniProt.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   MYO1F_HUMAN             Reviewed;        1098 AA.
AC   O00160; Q8WWN7;
DE   RecName: Full=Unconventional myosin-If;
DE   AltName: Full=Myosin-Ie;
GN   Name=MYO1F;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0043312; P:neutrophil degranulation; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0045088; P:regulation of innate immune response; IEA:Ensembl.
//
ID   MYO1G_HUMAN             Reviewed;        1018 AA.
AC   B0I1T2; Q8TEI9; Q8TES2; Q96BE2; Q96RI5; Q96RI6;
DE   RecName: Full=Unconventional myosin-Ig;
DE   Contains:
DE     RecName: Full=Minor histocompatibility antigen HA-2;
DE              Short=mHag HA-2;
GN   Name=MYO1G; Synonyms=HA2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYO1H_HUMAN             Reviewed;        1032 AA.
AC   Q8N1T3; F5H3C6;
DE   RecName: Full=Unconventional myosin-Ih;
DE   AltName: Full=Myosin-1H;
GN   Name=MYO1H;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYO1E_HUMAN             Reviewed;        1108 AA.
AC   Q12965; Q14778;
DE   RecName: Full=Unconventional myosin-Ie;
DE   AltName: Full=Myosin-Ic;
DE   AltName: Full=Unconventional myosin 1E;
GN   Name=MYO1E; Synonyms=MYO1C;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042623; F:ATPase activity, coupled; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; TAS:UniProtKB.
DR   GO; GO:0003774; F:motor activity; TAS:ProtInc.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030048; P:actin filament-based movement; TAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.
DR   GO; GO:0003094; P:glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035166; P:post-embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   MYO3A_HUMAN             Reviewed;        1616 AA.
AC   Q8NEV4; Q5VZ28; Q8WX17; Q9NYS8;
DE   RecName: Full=Myosin-IIIa;
DE            EC=2.7.11.1;
GN   Name=MYO3A;
DR   GuidetoPHARMACOLOGY; 2112; -.
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0043531; F:ADP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; IDA:UniProtKB.
DR   GO; GO:0060002; F:plus-end directed microfilament motor activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   MYO3B_HUMAN             Reviewed;        1341 AA.
AC   Q8WXR4; B8ZZR2; Q53QE1; Q53T08; Q8IX64; Q8IX65; Q8IX66; Q8IX67;
AC   Q8IX68; Q96N94;
DE   RecName: Full=Myosin-IIIb;
DE            EC=2.7.11.1;
GN   Name=MYO3B;
DR   GuidetoPHARMACOLOGY; 2113; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; IEA:Ensembl.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   MYO5A_HUMAN             Reviewed;        1855 AA.
AC   Q9Y4I1; A8MZC5; O60653; Q07902; Q16249; Q9UE30; Q9UE31;
DE   RecName: Full=Unconventional myosin-Va;
DE   AltName: Full=Dilute myosin heavy chain, non-muscle;
DE   AltName: Full=Myosin heavy chain 12;
DE   AltName: Full=Myosin-12;
DE   AltName: Full=Myoxin;
GN   Name=MYO5A; Synonyms=MYH12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0000146; F:microfilament motor activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; NAS:UniProtKB.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0051643; P:endoplasmic reticulum localization; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0031987; P:locomotion involved in locomotory behavior; IEA:Ensembl.
DR   GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032402; P:melanosome transport; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0031585; P:regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0032252; P:secretory granule localization; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   MYO5B_HUMAN             Reviewed;        1848 AA.
AC   Q9ULV0; B0I1R3;
DE   RecName: Full=Unconventional myosin-Vb;
GN   Name=MYO5B; Synonyms=KIAA1119;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000146; F:microfilament motor activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   MYO5C_HUMAN             Reviewed;        1742 AA.
AC   Q9NQX4;
DE   RecName: Full=Unconventional myosin-Vc;
GN   Name=MYO5C;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYO6_HUMAN              Reviewed;        1294 AA.
AC   Q9UM54; A6H8V4; E1P540; Q5TEM5; Q5TEM6; Q5TEM7; Q9BZZ7; Q9UEG2;
DE   RecName: Full=Unconventional myosin-VI;
DE   AltName: Full=Unconventional myosin-6;
GN   Name=MYO6; Synonyms=KIAA0389;
DR   GO; GO:0003779; F:actin binding; TAS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0043531; F:ADP binding; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; ISS:UniProtKB.
DR   GO; GO:0060001; F:minus-end directed microfilament motor activity; NAS:UniProtKB.
DR   GO; GO:0003774; F:motor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030048; P:actin filament-based movement; ISS:UniProtKB.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0014047; P:glutamate secretion; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0051046; P:regulation of secretion; IMP:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   MYO7A_HUMAN             Reviewed;        2215 AA.
AC   Q13402; B9A011; F8VUN5; P78427; Q13321; Q14785; Q92821; Q92822;
DE   RecName: Full=Unconventional myosin-VIIa;
GN   Name=MYO7A; Synonyms=USH1B;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IEA:Ensembl.
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IMP:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0030048; P:actin filament-based movement; IDA:UniProtKB.
DR   GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
DR   GO; GO:0050957; P:equilibrioception; IMP:HGNC.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IC:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0007040; P:lysosome organization; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0001845; P:phagolysosome assembly; IEA:Ensembl.
DR   GO; GO:0051904; P:pigment granule transport; IEA:Ensembl.
DR   GO; GO:0048563; P:post-embryonic organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   MYO7B_HUMAN             Reviewed;        2116 AA.
AC   Q6PIF6; Q14786; Q8TEE1;
DE   RecName: Full=Unconventional myosin-VIIb;
GN   Name=MYO7B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
//
ID   MYO9A_HUMAN             Reviewed;        2548 AA.
AC   B2RTY4; B0I1T5; C9IYB3; C9JA86; Q14787; Q3YLD7; Q3YLD8; Q6P986;
AC   Q9H8T5; Q9NTG2; Q9NUY2; Q9UEP3; Q9UNJ2;
DE   RecName: Full=Unconventional myosin-IXa;
DE   AltName: Full=Unconventional myosin-9a;
GN   Name=MYO9A; Synonyms=MYR7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003774; F:motor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   MYO9B_HUMAN             Reviewed;        2157 AA.
AC   Q13459; O75314; Q9NUJ2; Q9UHN0;
DE   RecName: Full=Unconventional myosin-IXb;
DE   AltName: Full=Unconventional myosin-9b;
GN   Name=MYO9B; Synonyms=MYR5;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0030898; F:actin-dependent ATPase activity; IEA:Ensembl.
DR   GO; GO:0043531; F:ADP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0000146; F:microfilament motor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0030048; P:actin filament-based movement; TAS:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0072673; P:lamellipodium morphogenesis; IEA:Ensembl.
DR   GO; GO:0048246; P:macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:0002548; P:monocyte chemotaxis; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; IC:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   MYOC_HUMAN              Reviewed;         504 AA.
AC   Q99972; B2RD84; O00620; Q7Z6Q9;
DE   RecName: Full=Myocilin;
DE   AltName: Full=Myocilin 55 kDa subunit;
DE   AltName: Full=Trabecular meshwork-induced glucocorticoid response protein;
DE   Contains:
DE     RecName: Full=Myocilin, N-terminal fragment;
DE     AltName: Full=Myocilin 20 kDa N-terminal fragment;
DE   Contains:
DE     RecName: Full=Myocilin, C-terminal fragment;
DE     AltName: Full=Myocilin 35 kDa N-terminal fragment;
DE   Flags: Precursor;
GN   Name=MYOC; Synonyms=GLC1A, TIGR;
DR   GO; GO:0001968; F:fibronectin binding; IPI:UniProtKB.
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0032027; F:myosin light chain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060348; P:bone development; ISS:UniProtKB.
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; ISS:UniProtKB.
DR   GO; GO:0038133; P:ERBB2-ERBB3 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; ISS:UniProtKB.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0038031; P:non-canonical Wnt signaling pathway via JNK cascade; IMP:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0014734; P:skeletal muscle hypertrophy; ISS:UniProtKB.
//
ID   MYOD1_HUMAN             Reviewed;         320 AA.
AC   P15172; O75321;
DE   RecName: Full=Myoblast determination protein 1;
DE   AltName: Full=Class C basic helix-loop-helix protein 1;
DE            Short=bHLHc1;
DE   AltName: Full=Myogenic factor 3;
DE            Short=Myf-3;
GN   Name=MYOD1; Synonyms=BHLHC1, MYF3, MYOD;
DR   GO; GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; ISS:BHF-UCL.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; ISS:UniProtKB.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0071453; P:cellular response to oxygen levels; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0043966; P:histone H3 acetylation; ISS:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0042693; P:muscle cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0007518; P:myoblast fate determination; IEA:Ensembl.
DR   GO; GO:0014904; P:myotube cell development; IDA:BHF-UCL.
DR   GO; GO:0014908; P:myotube differentiation involved in skeletal muscle regeneration; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:1901741; P:positive regulation of myoblast fusion; IDA:BHF-UCL.
DR   GO; GO:0043415; P:positive regulation of skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0043503; P:skeletal muscle fiber adaptation; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
//
ID   MYOF_HUMAN              Reviewed;        2061 AA.
AC   Q9NZM1; B3KQN5; Q5VWW2; Q5VWW3; Q5VWW4; Q5VWW5; Q7Z642; Q8IWH0;
AC   Q9HBU3; Q9NZM0; Q9ULL3; Q9Y4U4;
DE   RecName: Full=Myoferlin;
DE   AltName: Full=Fer-1-like protein 3;
GN   Name=MYOF; Synonyms=FER1L3, KIAA1207;
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0001778; P:plasma membrane repair; ISS:UniProtKB.
DR   GO; GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
//
ID   MYOG_HUMAN              Reviewed;         224 AA.
AC   P15173; Q53XW6;
DE   RecName: Full=Myogenin;
DE   AltName: Full=Class C basic helix-loop-helix protein 3;
DE            Short=bHLHc3;
DE   AltName: Full=Myogenic factor 4;
DE            Short=Myf-4;
GN   Name=MYOG; Synonyms=BHLHC3, MYF4;
DR   GO; GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0070888; F:E-box binding; ISS:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; TAS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; ISS:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; TAS:BHF-UCL.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0042693; P:muscle cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0014737; P:positive regulation of muscle atrophy; ISS:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; ISS:UniProtKB.
DR   GO; GO:0048743; P:positive regulation of skeletal muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:1901739; P:regulation of myoblast fusion; ISS:UniProtKB.
DR   GO; GO:0014842; P:regulation of satellite cell proliferation; ISS:UniProtKB.
DR   GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; ISS:UniProtKB.
DR   GO; GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; ISS:UniProtKB.
DR   GO; GO:0014873; P:response to muscle activity involved in regulation of muscle adaptation; ISS:UniProtKB.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; TAS:ProtInc.
DR   GO; GO:0014891; P:striated muscle atrophy; ISS:UniProtKB.
//
ID   MYOM1_HUMAN             Reviewed;        1685 AA.
AC   P52179; Q14BD6; Q6H969; Q6ZUU0;
DE   RecName: Full=Myomesin-1;
DE   AltName: Full=190 kDa connectin-associated protein;
DE   AltName: Full=190 kDa titin-associated protein;
DE   AltName: Full=Myomesin family member 1;
GN   Name=MYOM1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
//
ID   MYOM2_HUMAN             Reviewed;        1465 AA.
AC   P54296; Q7Z3Y2;
DE   RecName: Full=Myomesin-2;
DE   AltName: Full=165 kDa connectin-associated protein;
DE   AltName: Full=165 kDa titin-associated protein;
DE   AltName: Full=M-protein;
DE   AltName: Full=Myomesin family member 2;
GN   Name=MYOM2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   MYOM3_HUMAN             Reviewed;        1437 AA.
AC   Q5VTT5; A6NF75; Q5VTT6; Q6AWC0; Q6AWC1; Q6NXF9; Q6ZRG7; Q7Z3G9;
AC   Q8NA11; Q96C54;
DE   RecName: Full=Myomesin-3;
DE   AltName: Full=Myomesin family member 3;
GN   Name=MYOM3;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
//
ID   MYOME_HUMAN             Reviewed;        2346 AA.
AC   Q5VU43; A2RU15; O75042; O75065; Q2YDC1; Q5VU42; Q5VU44; Q5VU45;
AC   Q5VU46; Q5VU47; Q5VU48; Q5VU49; Q68DU2; Q6AZ93; Q6PK88; Q86T40;
AC   Q86TB2; Q8N3W0; Q8TAY9; Q9HCP2; Q9HCP3; Q9HCP4; Q9HCP5;
DE   RecName: Full=Myomegalin;
DE   AltName: Full=Cardiomyopathy-associated protein 2;
DE   AltName: Full=Phosphodiesterase 4D-interacting protein;
GN   Name=PDE4DIP; Synonyms=CMYA2, KIAA0454, KIAA0477, MMGL;
DR   GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043623; P:cellular protein complex assembly; ISS:UniProtKB.
//
ID   MYOTI_HUMAN             Reviewed;         498 AA.
AC   Q9UBF9; A0A4R6; B4DT79;
DE   RecName: Full=Myotilin;
DE   AltName: Full=57 kDa cytoskeletal protein;
DE   AltName: Full=Myofibrillar titin-like Ig domains protein;
DE   AltName: Full=Titin immunoglobulin domain protein;
GN   Name=MYOT; Synonyms=TTID;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   MYOV2_HUMAN             Reviewed;          57 AA.
AC   Q8WXC6; Q8N110;
DE   RecName: Full=Myeloma-overexpressed gene 2 protein;
GN   Name=MYEOV2;
//
ID   MYOZ1_HUMAN             Reviewed;         299 AA.
AC   Q9NP98; Q9H1I7;
DE   RecName: Full=Myozenin-1;
DE   AltName: Full=Calsarcin-2;
DE   AltName: Full=Filamin-, actinin- and telethonin-binding protein;
DE   AltName: Full=Protein FATZ;
GN   Name=MYOZ1; Synonyms=MYOZ;
DR   GO; GO:0051373; F:FATZ binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030239; P:myofibril assembly; TAS:UniProtKB.
//
ID   MYOZ2_HUMAN             Reviewed;         264 AA.
AC   Q9NPC6; O43415; Q9HB92;
DE   RecName: Full=Myozenin-2;
DE   AltName: Full=Calsarcin-1;
DE   AltName: Full=FATZ-related protein 2;
GN   Name=MYOZ2; Synonyms=C4orf5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030346; F:protein phosphatase 2B binding; NAS:UniProtKB.
DR   GO; GO:0031433; F:telethonin binding; IPI:BHF-UCL.
//
ID   MYOZ3_HUMAN             Reviewed;         251 AA.
AC   Q8TDC0; B2R9Q4; D3DQG9; Q8IVM1; Q8IVN1;
DE   RecName: Full=Myozenin-3;
DE   AltName: Full=Calsarcin-3;
DE   AltName: Full=FATZ-related protein 3;
GN   Name=MYOZ3; Synonyms=FRP3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   MYP0_HUMAN              Reviewed;         248 AA.
AC   P25189; Q16072; Q5VTH4; Q92677; Q9BR67;
DE   RecName: Full=Myelin protein P0;
DE   AltName: Full=Myelin peripheral protein;
DE            Short=MPP;
DE   AltName: Full=Myelin protein zero;
DE   Flags: Precursor;
GN   Name=MPZ;
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0045217; P:cell-cell junction maintenance; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   MYP2_HUMAN              Reviewed;         132 AA.
AC   P02689; Q6FHL4;
DE   RecName: Full=Myelin P2 protein;
DE   AltName: Full=Peripheral myelin protein 2;
GN   Name=PMP2;
DR   GO; GO:0015485; F:cholesterol binding; IDA:UniProtKB.
DR   GO; GO:0005504; F:fatty acid binding; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; IEA:Ensembl.
//
ID   MYPC1_HUMAN             Reviewed;        1141 AA.
AC   Q00872; B4DKR5; B7Z8G8; B7ZL02; B7ZL09; B7ZL10; E7ESM5; E7EWS6;
AC   G3XAE8; Q15497; Q17RR7; Q569K7; Q86T48; Q86TC8; Q8N3L2;
DE   RecName: Full=Myosin-binding protein C, slow-type;
DE            Short=Slow MyBP-C;
DE   AltName: Full=C-protein, skeletal muscle slow isoform;
GN   Name=MYBPC1; Synonyms=MYBPCS;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0031432; F:titin binding; ISS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
//
ID   MYPC2_HUMAN             Reviewed;        1141 AA.
AC   Q14324; A1L4G9;
DE   RecName: Full=Myosin-binding protein C, fast-type;
DE            Short=Fast MyBP-C;
DE   AltName: Full=C-protein, skeletal muscle fast isoform;
GN   Name=MYBPC2; Synonyms=MYBPCF;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
//
ID   MYPC3_HUMAN             Reviewed;        1274 AA.
AC   Q14896; A5PL00; Q16410; Q6R2F7; Q9UE27; Q9UM53;
DE   RecName: Full=Myosin-binding protein C, cardiac-type;
DE            Short=Cardiac MyBP-C;
DE   AltName: Full=C-protein, cardiac muscle isoform;
GN   Name=MYBPC3;
DR   GO; GO:0001671; F:ATPase activator activity; ISS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017022; F:myosin binding; IDA:BHF-UCL.
DR   GO; GO:0032036; F:myosin heavy chain binding; IPI:BHF-UCL.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:BHF-UCL.
DR   GO; GO:0031432; F:titin binding; NAS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0031034; P:myosin filament assembly; IEA:Ensembl.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; ISS:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0032971; P:regulation of muscle filament sliding; ISS:BHF-UCL.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   MYPN_HUMAN              Reviewed;        1320 AA.
AC   Q86TC9; Q5VV35; Q5VV36; Q86T37; Q8N3L4; Q96K90; Q96KF5;
DE   RecName: Full=Myopalladin;
DE   AltName: Full=145 kDa sarcomeric protein;
GN   Name=MYPN; Synonyms=MYOP;
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:BHF-UCL.
DR   GO; GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IMP:BHF-UCL.
//
ID   MYPOP_HUMAN             Reviewed;         399 AA.
AC   Q86VE0;
DE   RecName: Full=Myb-related transcription factor, partner of profilin;
DE   AltName: Full=Myb-related protein p42POP;
DE   AltName: Full=Partner of profilin;
GN   Name=MYPOP; Synonyms=P42POP;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYPR_HUMAN              Reviewed;         277 AA.
AC   P60201; P04400; P06905; Q502Y1; Q6FHZ6;
DE   RecName: Full=Myelin proteolipid protein;
DE            Short=PLP;
DE   AltName: Full=Lipophilin;
GN   Name=PLP1; Synonyms=PLP;
DR   GO; GO:0019911; F:structural constituent of myelin sheath; IEA:Ensembl.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0008366; P:axon ensheathment; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   MYPT1_HUMAN             Reviewed;        1030 AA.
AC   O14974; B4DZ09; F8VWB4; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 12A;
DE   AltName: Full=Myosin phosphatase-targeting subunit 1;
DE            Short=Myosin phosphatase target subunit 1;
DE   AltName: Full=Protein phosphatase myosin-binding subunit;
GN   Name=PPP1R12A; Synonyms=MBS, MYPT1;
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0019208; F:phosphatase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:ProtInc.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   MYPT2_HUMAN             Reviewed;         982 AA.
AC   O60237; A8MYF5; B7ZMN6; Q2TAI8; Q5T506; Q5VUK2; Q8N179; Q9HCB7;
AC   Q9HCB8;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 12B;
DE   AltName: Full=Myosin phosphatase-targeting subunit 2;
DE            Short=Myosin phosphatase target subunit 2;
GN   Name=PPP1R12B; Synonyms=MYPT2;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   MYRIP_HUMAN             Reviewed;         859 AA.
AC   Q8NFW9; B3KWM3; B3KWW4; B7Z2H1; B7Z9V3; G3XAI8; Q32M41; Q32M42;
AC   Q569F7; Q8IUF5; Q9Y3V4;
DE   RecName: Full=Rab effector MyRIP;
DE   AltName: Full=Exophilin-8;
DE   AltName: Full=Myosin-VIIa- and Rab-interacting protein;
DE   AltName: Full=Synaptotagmin-like protein lacking C2 domains C;
DE            Short=SlaC2-c;
DE            Short=Slp homolog lacking C2 domains c;
GN   Name=MYRIP; Synonyms=SLAC2C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.
//
ID   MYSM1_HUMAN             Reviewed;         828 AA.
AC   Q5VVJ2; A8KA54; B3KX65; Q68DD3; Q6AI53; Q7Z3G8; Q96PX3;
DE   RecName: Full=Histone H2A deubiquitinase MYSM1;
DE            Short=2A-DUB;
DE            EC=3.4.19.-;
DE   AltName: Full=Myb-like, SWIRM and MPN domain-containing protein 1;
GN   Name=MYSM1; Synonyms=KIAA1915;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IMP:UniProtKB.
DR   GO; GO:0035522; P:monoubiquitinated histone H2A deubiquitination; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYT1L_HUMAN             Reviewed;        1186 AA.
AC   Q9UL68; A7E2C7; B2RP54; Q6IQ17; Q9UPP6;
DE   RecName: Full=Myelin transcription factor 1-like protein;
DE            Short=MyT1-L;
DE            Short=MyT1L;
GN   Name=MYT1L; Synonyms=KIAA1106;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYT1_HUMAN              Reviewed;        1121 AA.
AC   Q01538; E1P5H0; F5H7M8; O94922; Q7Z5W2; Q9UPV2;
DE   RecName: Full=Myelin transcription factor 1;
DE            Short=MyT1;
DE   AltName: Full=Myelin transcription factor I;
DE            Short=MyTI;
DE   AltName: Full=PLPB1;
DE   AltName: Full=Proteolipid protein-binding protein;
GN   Name=MYT1; Synonyms=KIAA0835, KIAA1050, MTF1, MYTI, PLPB1;
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MYZAP_HUMAN             Reviewed;         466 AA.
AC   P0CAP1; D2E9U7; Q6EER8; Q6EES2; Q6EEV3; Q6EF00; Q6EF01; Q6EF02;
AC   Q6EF46; Q6EFN8; Q6EM48; Q6K046; Q6K050; Q6K051; Q6ZQZ3; Q8NC58;
AC   Q8NCF3; Q96DI5; Q96JB7; Q96NF5;
DE   RecName: Full=Myocardial zonula adherens protein;
DE   AltName: Full=GRINL1A upstream protein;
DE            Short=Gup;
DE   Flags: Precursor;
GN   Name=MYZAP; Synonyms=MYOZAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
//
ID   MZB1_HUMAN              Reviewed;         189 AA.
AC   Q8WU39; D2IYS0; Q7Z6N2; Q96RL5; Q9P0T3;
DE   RecName: Full=Marginal zone B- and B1-cell-specific protein;
DE   AltName: Full=Mesenteric estrogen-dependent adipose 7;
DE            Short=MEDA-7;
DE   AltName: Full=Plasma cell-induced resident endoplasmic reticulum protein;
DE            Short=Plasma cell-induced resident ER protein;
DE            Short=pERp1;
DE   AltName: Full=Proapoptotic caspase adapter protein;
DE   Flags: Precursor;
GN   Name=MZB1; Synonyms=MEDA7, PACAP; ORFNames=HSPC190;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0033622; P:integrin activation; ISS:UniProtKB.
DR   GO; GO:2001274; P:negative regulation of glucose import in response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0002642; P:positive regulation of immunoglobulin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0030888; P:regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
//
ID   MZF1_HUMAN              Reviewed;         734 AA.
AC   P28698; M0QXU0; Q7Z729; Q96I71; Q9NRY0; Q9UBW2;
DE   RecName: Full=Myeloid zinc finger 1;
DE            Short=MZF-1;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 6;
DE   AltName: Full=Zinc finger protein 42;
GN   Name=MZF1; Synonyms=MZF, ZNF42, ZSCAN6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   MZT1_HUMAN              Reviewed;          82 AA.
AC   Q08AG7; Q5W0P5;
DE   RecName: Full=Mitotic-spindle organizing protein 1;
DE   AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1;
GN   Name=MZT1; Synonyms=C13orf37, MOZART1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033566; P:gamma-tubulin complex localization; IMP:UniProtKB.
//
ID   MZT2A_HUMAN             Reviewed;         158 AA.
AC   Q6P582; Q3SWV8; Q8WVB2;
DE   RecName: Full=Mitotic-spindle organizing protein 2A;
DE   AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A;
GN   Name=MZT2A; Synonyms=FAM128A, MOZART2A;
//
ID   MZT2B_HUMAN             Reviewed;         158 AA.
AC   Q6NZ67; Q96CG4;
DE   RecName: Full=Mitotic-spindle organizing protein 2B;
DE   AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2B;
GN   Name=MZT2B; Synonyms=FAM128B, MOZART2B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   N2DL2_HUMAN             Reviewed;         246 AA.
AC   Q9BZM5; Q5VUN4;
DE   RecName: Full=NKG2D ligand 2;
DE            Short=N2DL-2;
DE            Short=NKG2DL2;
DE   AltName: Full=ALCAN-alpha;
DE   AltName: Full=Retinoic acid early transcript 1H;
DE   AltName: Full=UL16-binding protein 2;
DE   Flags: Precursor;
GN   Name=ULBP2; Synonyms=N2DL2, RAET1H; ORFNames=UNQ463/PRO791;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IDA:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0030101; P:natural killer cell activation; IDA:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IDA:UniProtKB.
//
ID   N2DL1_HUMAN             Reviewed;         244 AA.
AC   Q9BZM6; Q5VY81; Q8IZW3; Q8IZX6;
DE   RecName: Full=NKG2D ligand 1;
DE            Short=N2DL-1;
DE            Short=NKG2DL1;
DE   AltName: Full=ALCAN-beta;
DE   AltName: Full=Retinoic acid early transcript 1I;
DE   AltName: Full=UL16-binding protein 1;
DE   Flags: Precursor;
GN   Name=ULBP1; Synonyms=N2DL1, RAET1I;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IDA:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0030101; P:natural killer cell activation; IDA:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   N2DL3_HUMAN             Reviewed;         244 AA.
AC   Q9BZM4; Q5VY82; Q8IZX5; Q8TE75;
DE   RecName: Full=NKG2D ligand 3;
DE            Short=N2DL-3;
DE            Short=NKG2DL3;
DE   AltName: Full=ALCAN-gamma;
DE   AltName: Full=Retinoic acid early transcript 1N;
DE   Flags: Precursor;
GN   Name=ULBP3; Synonyms=N2DL3, RAET1N;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IDA:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0030101; P:natural killer cell activation; IDA:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   N2DL4_HUMAN             Reviewed;         263 AA.
AC   Q8TD07; A6YF59; Q5VYB7; Q5VYB8; Q8TEZ2; Q96L41;
DE   RecName: Full=NKG2D ligand 4;
DE            Short=N2DL-4;
DE            Short=NKG2DL4;
DE   AltName: Full=Lymphocyte effector toxicity activation ligand;
DE   AltName: Full=RAE-1-like transcript 4;
DE            Short=RL-4;
DE   AltName: Full=Retinoic acid early transcript 1E;
DE   Flags: Precursor;
GN   Name=RAET1E; Synonyms=LETAL, N2DL4, ULBP4; ORFNames=UNQ1867/PRO4303;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0001913; P:T cell mediated cytotoxicity; IBA:RefGenome.
//
ID   N42L1_HUMAN             Reviewed;         243 AA.
AC   Q5TBK1; A4QN21; Q5TBK0;
DE   RecName: Full=NEDD4-binding protein 2-like 1;
GN   Name=N4BP2L1; Synonyms=CG081;
//
ID   N42L2_HUMAN             Reviewed;         583 AA.
AC   Q92802; A3KME8;
DE   RecName: Full=NEDD4-binding protein 2-like 2;
DE   AltName: Full=Phosphonoformate immuno-associated protein 5;
GN   Name=N4BP2L2; Synonyms=CG005, PFAAP5;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:UniProt.
DR   GO; GO:1902037; P:negative regulation of hematopoietic stem cell differentiation; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProt.
DR   GO; GO:1902035; P:positive regulation of hematopoietic stem cell proliferation; IMP:UniProt.
//
ID   N4BP1_HUMAN             Reviewed;         896 AA.
AC   O75113; A7MD49; Q2YDX1;
DE   RecName: Full=NEDD4-binding protein 1;
DE            Short=N4BP1;
GN   Name=N4BP1; Synonyms=KIAA0615;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034644; P:cellular response to UV; IMP:BHF-UCL.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.
//
ID   N4BP2_HUMAN             Reviewed;        1770 AA.
AC   Q86UW6; A0AVR3; Q9NVK2; Q9P2D4;
DE   RecName: Full=NEDD4-binding protein 2;
DE            Short=N4BP2;
DE            EC=3.-.-.-;
DE   AltName: Full=BCL-3-binding protein;
GN   Name=N4BP2; Synonyms=B3BP, KIAA1413;
DR   GO; GO:0005524; F:ATP binding; IDA:MGI.
DR   GO; GO:0046404; F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; IDA:MGI.
DR   GO; GO:0004519; F:endonuclease activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0016310; P:phosphorylation; IDA:GOC.
//
ID   N4BP3_HUMAN             Reviewed;         544 AA.
AC   O15049; B4DIL3; D3DWP3; Q6ZSQ6; Q7Z6I3;
DE   RecName: Full=NEDD4-binding protein 3;
DE            Short=N4BP3;
GN   Name=N4BP3; Synonyms=KIAA0341;
//
ID   N62CL_HUMAN             Reviewed;         184 AA.
AC   Q9H1M0; D3DUX4; Q8WVL6; Q9NXP2;
DE   RecName: Full=Nucleoporin-62 C-terminal-like protein;
GN   Name=NUP62CL; Synonyms=NUP62L;
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   N6MT2_HUMAN             Reviewed;         214 AA.
AC   Q8WVE0; B5G4V1;
DE   RecName: Full=N(6)-adenine-specific DNA methyltransferase 2;
DE            EC=2.1.1.-;
GN   Name=N6AMT2;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   NAA11_HUMAN             Reviewed;         229 AA.
AC   Q9BSU3; Q66K19; Q6P479;
DE   RecName: Full=N-alpha-acetyltransferase 11;
DE            EC=2.3.1.88;
DE   AltName: Full=N-terminal acetyltransferase complex ARD1 subunit homolog B;
DE            Short=hARD2;
DE   AltName: Full=NatA catalytic subunit Naa11;
GN   Name=NAA11; Synonyms=ARD1B, ARD2;
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; IDA:UniProtKB.
//
ID   NAA10_HUMAN             Reviewed;         235 AA.
AC   P41227; A6NM98;
DE   RecName: Full=N-alpha-acetyltransferase 10;
DE            EC=2.3.1.-;
DE            EC=2.3.1.88;
DE   AltName: Full=N-terminal acetyltransferase complex ARD1 subunit homolog A;
DE   AltName: Full=NatA catalytic subunit Naa10;
GN   Name=NAA10; Synonyms=ARD1, ARD1A, TE2;
DR   GO; GO:0008080; F:N-acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006323; P:DNA packaging; TAS:ProtInc.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; TAS:ProtInc.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; IDA:UniProtKB.
//
ID   NAA15_HUMAN             Reviewed;         866 AA.
AC   Q9BXJ9; D3DNY6; Q52LG9; Q8IWH4; Q8NEV2; Q9H8P6;
DE   RecName: Full=N-alpha-acetyltransferase 15, NatA auxiliary subunit;
DE   AltName: Full=Gastric cancer antigen Ga19;
DE   AltName: Full=N-terminal acetyltransferase;
DE   AltName: Full=NMDA receptor-regulated protein 1;
DE   AltName: Full=Protein tubedown-1;
DE   AltName: Full=Tbdn100;
GN   Name=NAA15; Synonyms=GA19, NARG1, NATH, TBDN100;
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProt.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProt.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NAA16_HUMAN             Reviewed;         864 AA.
AC   Q6N069; B0QZ59; Q5VSP9; Q6P2D5; Q8N5J3; Q8N870;
DE   RecName: Full=N-alpha-acetyltransferase 16, NatA auxiliary subunit;
DE   AltName: Full=NMDA receptor-regulated 1-like protein;
DE            Short=NARG1-like protein;
GN   Name=NAA16; Synonyms=NARG1L, NAT2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProt.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProt.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
//
ID   NAA20_HUMAN             Reviewed;         178 AA.
AC   P61599; A6NHA3; B2R4G4; Q5TFT7; Q9D7H8; Q9H0Y4; Q9NQH6; Q9Y6D2;
DE   RecName: Full=N-alpha-acetyltransferase 20;
DE            EC=2.3.1.88;
DE   AltName: Full=Methionine N-acetyltransferase;
DE   AltName: Full=N-acetyltransferase 5;
DE   AltName: Full=N-terminal acetyltransferase B complex catalytic subunit NAA20;
DE   AltName: Full=N-terminal acetyltransferase B complex catalytic subunit NAT5;
DE            Short=NatB complex subunit NAT5;
DE   AltName: Full=NatB catalytic subunit;
GN   Name=NAA20; Synonyms=NAT5;
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IEA:UniProtKB-EC.
//
ID   NAA25_HUMAN             Reviewed;         972 AA.
AC   Q14CX7; A0JLU7; Q6MZH1; Q7Z4N6; Q9H911;
DE   RecName: Full=N-alpha-acetyltransferase 25, NatB auxiliary subunit;
DE   AltName: Full=Mitochondrial distribution and morphology protein 20;
DE   AltName: Full=N-terminal acetyltransferase B complex subunit MDM20;
DE            Short=NatB complex subunit MDM20;
DE   AltName: Full=N-terminal acetyltransferase B complex subunit NAA25;
DE   AltName: Full=p120;
GN   Name=NAA25; Synonyms=C12orf30, MDM20, NAP1;
//
ID   NAA30_HUMAN             Reviewed;         362 AA.
AC   Q147X3; Q0IIN2;
DE   RecName: Full=N-alpha-acetyltransferase 30;
DE            EC=2.3.1.88;
DE   AltName: Full=N-acetyltransferase 12;
DE   AltName: Full=N-acetyltransferase MAK3 homolog;
DE   AltName: Full=NatC catalytic subunit;
GN   Name=NAA30; Synonyms=C14orf35, MAK3, NAT12;
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
//
ID   NAA35_HUMAN             Reviewed;         725 AA.
AC   Q5VZE5; Q9H631; Q9H703;
DE   RecName: Full=N-alpha-acetyltransferase 35, NatC auxiliary subunit;
DE   AltName: Full=Embryonic growth-associated protein homolog;
DE   AltName: Full=Protein MAK10 homolog;
GN   Name=NAA35; Synonyms=EGAP, MAK10;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0048659; P:smooth muscle cell proliferation; ISS:UniProtKB.
//
ID   NAA50_HUMAN             Reviewed;         169 AA.
AC   Q9GZZ1; D3DN74; Q68DQ1;
DE   RecName: Full=N-alpha-acetyltransferase 50;
DE            EC=2.3.1.-;
DE   AltName: Full=N-acetyltransferase 13;
DE   AltName: Full=N-acetyltransferase 5;
DE            Short=hNAT5;
DE   AltName: Full=N-acetyltransferase san homolog;
DE            Short=hSAN;
DE   AltName: Full=NatE catalytic subunit;
GN   Name=NAA50; Synonyms=MAK3, NAT13, NAT5;
DR   GO; GO:0010485; F:H4 histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0052858; F:peptidyl-lysine N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:GOC.
DR   GO; GO:0071962; P:mitotic sister chromatid cohesion, centromeric; IDA:UniProtKB.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; TAS:HGNC.
//
ID   NAA40_HUMAN             Reviewed;         237 AA.
AC   Q86UY6; B4DR03; B4DU10; Q5HYL5; Q9H897;
DE   RecName: Full=N-alpha-acetyltransferase 40;
DE            EC=2.3.1.-;
DE   AltName: Full=N-acetyltransferase 11;
DE   AltName: Full=NatD catalytic subunit;
GN   Name=NAA40; Synonyms=NAT11;
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
//
ID   NAA60_HUMAN             Reviewed;         242 AA.
AC   Q9H7X0; B3KRQ0; B4DLZ0; B4DPZ8; B4DYC4; D3DUC2; E7EQ65; Q6IA31;
AC   Q6UX26;
DE   RecName: Full=N-alpha-acetyltransferase 60;
DE            EC=2.3.1.48;
DE            EC=2.3.1.88;
DE   AltName: Full=Histone acetyltransferase type B protein 4;
DE            Short=HAT4;
DE   AltName: Full=N-acetyltransferase 15;
DE   AltName: Full=NatF catalytic subunit;
GN   Name=NAA60; Synonyms=HAT4, NAT15; ORFNames=UNQ2771/PRO7155;
DR   GO; GO:0010485; F:H4 histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004596; F:peptide alpha-N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; ISS:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0017196; P:N-terminal peptidyl-methionine acetylation; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
//
ID   NAAA_HUMAN              Reviewed;         359 AA.
AC   Q02083; Q5KTF2; Q96EY2; Q9BRA8;
DE   RecName: Full=N-acylethanolamine-hydrolyzing acid amidase;
DE            EC=3.5.1.-;
DE   AltName: Full=Acid ceramidase-like protein;
DE   AltName: Full=N-acylsphingosine amidohydrolase-like;
DE            Short=ASAH-like protein;
DE   Contains:
DE     RecName: Full=N-acylethanolamine-hydrolyzing acid amidase subunit alpha;
DE   Contains:
DE     RecName: Full=N-acylethanolamine-hydrolyzing acid amidase subunit beta;
DE   Flags: Precursor;
GN   Name=NAAA; Synonyms=ASAHL, PLT;
DR   GuidetoPHARMACOLOGY; 1402; -.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IDA:MGI.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   NAB1_HUMAN              Reviewed;         487 AA.
AC   Q13506; O75383; O75384; Q6GTU1; Q9UEV1;
DE   RecName: Full=NGFI-A-binding protein 1;
DE   AltName: Full=EGR-1-binding protein 1;
DE   AltName: Full=Transcriptional regulatory protein p54;
GN   Name=NAB1;
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0045682; P:regulation of epidermis development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0014037; P:Schwann cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NAB2_HUMAN              Reviewed;         525 AA.
AC   Q15742; B2RAK3; O76006; Q14797;
DE   RecName: Full=NGFI-A-binding protein 2;
DE   AltName: Full=EGR-1-binding protein 2;
DE   AltName: Full=Melanoma-associated delayed early response protein;
DE            Short=Protein MADER;
GN   Name=NAB2; Synonyms=MADER;
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0016480; P:negative regulation of transcription from RNA polymerase III promoter; IDA:MGI.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0045682; P:regulation of epidermis development; IEA:Ensembl.
DR   GO; GO:0014037; P:Schwann cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NAC1_HUMAN              Reviewed;         973 AA.
AC   P32418; A8K6N1; D6W595; O95849; Q4QQG6; Q587I6; Q59GN4; Q9UBL8;
AC   Q9UD55; Q9UDN1; Q9UDN2; Q9UKX6;
DE   RecName: Full=Sodium/calcium exchanger 1;
DE   AltName: Full=Na(+)/Ca(2+)-exchange protein 1;
DE   AltName: Full=Solute carrier family 8 member 1;
DE   Flags: Precursor;
GN   Name=SLC8A1; Synonyms=CNC, NCX1;
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0005432; F:calcium:sodium antiporter activity; IDA:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:1901660; P:calcium ion export; IDA:BHF-UCL.
DR   GO; GO:0055074; P:calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0070509; P:calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; ISS:BHF-UCL.
DR   GO; GO:0055013; P:cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; ISS:BHF-UCL.
DR   GO; GO:0071313; P:cellular response to caffeine; ISS:BHF-UCL.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IDA:BHF-UCL.
DR   GO; GO:0060401; P:cytosolic calcium ion transport; TAS:BHF-UCL.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; ISS:BHF-UCL.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; ISS:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; IC:BHF-UCL.
DR   GO; GO:0044557; P:relaxation of smooth muscle; ISS:BHF-UCL.
DR   GO; GO:0071436; P:sodium ion export; IDA:BHF-UCL.
DR   GO; GO:0097369; P:sodium ion import; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0014829; P:vascular smooth muscle contraction; ISS:BHF-UCL.
//
ID   NAC2_HUMAN              Reviewed;         921 AA.
AC   Q9UPR5; B4DYQ9;
DE   RecName: Full=Sodium/calcium exchanger 2;
DE   AltName: Full=Na(+)/Ca(2+)-exchange protein 2;
DE   AltName: Full=Solute carrier family 8 member 2;
DE   Flags: Precursor;
GN   Name=SLC8A2; Synonyms=KIAA1087, NCX2;
DR   GO; GO:0005432; F:calcium:sodium antiporter activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NAC3_HUMAN              Reviewed;         927 AA.
AC   P57103; Q5K3P6; Q5K3P7; Q8IUE9; Q8IUF0; Q8NFI7; Q96QG1; Q96QG2;
DE   RecName: Full=Sodium/calcium exchanger 3;
DE   AltName: Full=Na(+)/Ca(2+)-exchange protein 3;
DE   AltName: Full=Solute carrier family 8 member 3;
DE   Flags: Precursor;
GN   Name=SLC8A3; Synonyms=NCX3;
DR   GO; GO:0005432; F:calcium:sodium antiporter activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:1990034; P:calcium ion export from cell; IEA:Ensembl.
DR   GO; GO:1990035; P:calcium ion import into cell; IEA:Ensembl.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NACA2_HUMAN             Reviewed;         215 AA.
AC   Q9H009; Q2VIR9;
DE   RecName: Full=Nascent polypeptide-associated complex subunit alpha-2;
DE   AltName: Full=Alpha-NAC-like;
DE   AltName: Full=Hom s 2.01;
DE   AltName: Full=Nascent polypeptide-associated complex subunit alpha-like;
DE            Short=NAC-alpha-like;
GN   Name=NACA2; Synonyms=NACAL;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NACAD_HUMAN             Reviewed;        1562 AA.
AC   O15069;
DE   RecName: Full=NAC-alpha domain-containing protein 1;
GN   Name=NACAD; Synonyms=KIAA0363;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NACAM_HUMAN             Reviewed;        2078 AA.
AC   E9PAV3;
DE   RecName: Full=Nascent polypeptide-associated complex subunit alpha, muscle-specific form;
DE   AltName: Full=Alpha-NAC, muscle-specific form;
DE            Short=skNAC;
GN   Name=NACA;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NACA_HUMAN              Reviewed;         215 AA.
AC   Q13765; A8MTN7; B2R4P8; F8VU71; Q3KQV4; Q53A18; Q53G46;
DE   RecName: Full=Nascent polypeptide-associated complex subunit alpha;
DE            Short=NAC-alpha;
DE   AltName: Full=Alpha-NAC;
DE   AltName: Allergen=Hom s 2;
GN   Name=NACA; ORFNames=HSD48;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017025; F:TBP-class protein binding; ISS:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
DR   GO; GO:0003231; P:cardiac ventricle development; ISS:BHF-UCL.
DR   GO; GO:0061384; P:heart trabecula morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0010664; P:negative regulation of striated muscle cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:1901227; P:negative regulation of transcription from RNA polymerase II promoter involved in heart development; ISS:BHF-UCL.
DR   GO; GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0048633; P:positive regulation of skeletal muscle tissue growth; ISS:BHF-UCL.
DR   GO; GO:1901228; P:positive regulation of transcription from RNA polymerase II promoter involved in heart development; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048742; P:regulation of skeletal muscle fiber development; ISS:BHF-UCL.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NACC1_HUMAN             Reviewed;         527 AA.
AC   Q96RE7;
DE   RecName: Full=Nucleus accumbens-associated protein 1;
DE            Short=NAC-1;
DE   AltName: Full=BTB/POZ domain-containing protein 14B;
GN   Name=NACC1; Synonyms=BTBD14B, NAC1;
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NACC2_HUMAN             Reviewed;         587 AA.
AC   Q96BF6;
DE   RecName: Full=Nucleus accumbens-associated protein 2;
DE            Short=NAC-2;
DE   AltName: Full=BTB/POZ domain-containing protein 14A;
GN   Name=NACC2; Synonyms=BTBD14A, NAC2;
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0034629; P:cellular protein complex localization; IDA:BHF-UCL.
DR   GO; GO:0016575; P:histone deacetylation; IDA:GOC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:1900477; P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:1902231; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IDA:BHF-UCL.
DR   GO; GO:0010608; P:posttranscriptional regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   NACP1_HUMAN             Reviewed;         213 AA.
AC   Q9BZK3;
DE   RecName: Full=Putative nascent polypeptide-associated complex subunit alpha-like protein;
DE   AltName: Full=Alpha-NAC pseudogene 1;
DE   AltName: Full=NAC-alpha pseudogene 1;
GN   Name=NACAP1; ORFNames=FKSG17;
//
ID   NADAP_HUMAN             Reviewed;         796 AA.
AC   Q9BWU0; A6NJ39; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9NVN2;
DE   RecName: Full=Kanadaptin;
DE   AltName: Full=Human lung cancer oncogene 3 protein;
DE            Short=HLC-3;
DE   AltName: Full=Kidney anion exchanger adapter protein;
DE   AltName: Full=Solute carrier family 4 anion exchanger member 1 adapter protein;
GN   Name=SLC4A1AP; ORFNames=HLC3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NADC_HUMAN              Reviewed;         297 AA.
AC   Q15274; Q53XW7; Q96G22; Q9BSG6;
DE   RecName: Full=Nicotinate-nucleotide pyrophosphorylase [carboxylating];
DE            EC=2.4.2.19;
DE   AltName: Full=Quinolinate phosphoribosyltransferase [decarboxylating];
DE            Short=QAPRTase;
DE            Short=QPRTase;
GN   Name=QPRT;
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0034213; P:quinolinate catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NADE_HUMAN              Reviewed;         706 AA.
AC   Q6IA69; Q86SN2; Q9HA25; Q9NVM8;
DE   RecName: Full=Glutamine-dependent NAD(+) synthetase;
DE            EC=6.3.5.1;
DE   AltName: Full=NAD(+) synthase [glutamine-hydrolyzing];
DE   AltName: Full=NAD(+) synthetase;
GN   Name=NADSYN1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0003952; F:NAD+ synthase (glutamine-hydrolyzing) activity; TAS:Reactome.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NADK_HUMAN              Reviewed;         446 AA.
AC   O95544; A6NNN3; A8K296; B7Z434; F5GXR5; Q5QPS4; Q9H2P2; Q9H931;
DE   RecName: Full=NAD kinase;
DE            EC=2.7.1.23;
DE   AltName: Full=Poly(P)/ATP NAD kinase;
GN   Name=NADK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IDA:UniProtKB.
DR   GO; GO:0046034; P:ATP metabolic process; NAS:UniProtKB.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NADL2_HUMAN             Reviewed;         795 AA.
AC   Q58DX5; Q658X9; Q6H9J8; Q6H9J9; Q6PG38;
DE   RecName: Full=Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2;
DE            Short=NAALADase L2;
GN   Name=NAALADL2;
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
//
ID   NAF1_HUMAN              Reviewed;         494 AA.
AC   Q96HR8; D3DP28; E9PAZ2;
DE   RecName: Full=H/ACA ribonucleoprotein complex non-core subunit NAF1;
DE            Short=hNAF1;
GN   Name=NAF1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   NAGAB_HUMAN             Reviewed;         411 AA.
AC   P17050;
DE   RecName: Full=Alpha-N-acetylgalactosaminidase;
DE            EC=3.2.1.49;
DE   AltName: Full=Alpha-galactosidase B;
DE   Flags: Precursor;
GN   Name=NAGA;
DR   GO; GO:0004557; F:alpha-galactosidase activity; IBA:RefGenome.
DR   GO; GO:0008456; F:alpha-N-acetylgalactosaminidase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IDA:UniProtKB.
DR   GO; GO:0019377; P:glycolipid catabolic process; IMP:UniProtKB.
DR   GO; GO:0016139; P:glycoside catabolic process; IBA:RefGenome.
DR   GO; GO:0046477; P:glycosylceramide catabolic process; IBA:RefGenome.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IBA:RefGenome.
//
ID   NAGA_HUMAN              Reviewed;         409 AA.
AC   Q9Y303; B4DL77; Q8WV54;
DE   RecName: Full=Putative N-acetylglucosamine-6-phosphate deacetylase;
DE            EC=3.5.1.25;
DE   AltName: Full=Amidohydrolase domain-containing protein 2;
DE   AltName: Full=GlcNAc 6-P deacetylase;
GN   Name=AMDHD2; ORFNames=CGI-14;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008448; F:N-acetylglucosamine-6-phosphate deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro.
DR   GO; GO:0019262; P:N-acetylneuraminate catabolic process; TAS:UniProtKB.
//
ID   NAGK_HUMAN              Reviewed;         344 AA.
AC   Q9UJ70; B4DLZ5; Q53HD5; Q6IA84; Q9BS29; Q9BVP0; Q9NV37;
DE   RecName: Full=N-acetyl-D-glucosamine kinase;
DE            Short=N-acetylglucosamine kinase;
DE            EC=2.7.1.59;
DE   AltName: Full=GlcNAc kinase;
GN   Name=NAGK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0045127; F:N-acetylglucosamine kinase activity; IDA:UniProtKB.
DR   GO; GO:0009384; F:N-acylmannosamine kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:GOC.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; TAS:ProtInc.
DR   GO; GO:0006051; P:N-acetylmannosamine metabolic process; TAS:ProtInc.
DR   GO; GO:0019262; P:N-acetylneuraminate catabolic process; TAS:UniProtKB.
//
ID   NAGPA_HUMAN             Reviewed;         515 AA.
AC   Q9UK23; B2RAS1; Q96EJ8;
DE   RecName: Full=N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase;
DE            EC=3.1.4.45;
DE   AltName: Full=Mannose 6-phosphate-uncovering enzyme;
DE   AltName: Full=Phosphodiester alpha-GlcNAcase;
DE   Flags: Precursor;
GN   Name=NAGPA;
DR   GO; GO:0003944; F:N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0007040; P:lysosome organization; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006622; P:protein targeting to lysosome; TAS:ProtInc.
//
ID   NAGS_HUMAN              Reviewed;         534 AA.
AC   Q8N159; B2RAZ9; Q8IWR4;
DE   RecName: Full=N-acetylglutamate synthase, mitochondrial;
DE            EC=2.3.1.1;
DE   AltName: Full=Amino-acid acetyltransferase;
DE   Contains:
DE     RecName: Full=N-acetylglutamate synthase long form;
DE   Contains:
DE     RecName: Full=N-acetylglutamate synthase short form;
DE   Contains:
DE     RecName: Full=N-acetylglutamate synthase conserved domain form;
DE   Flags: Precursor;
GN   Name=NAGS;
DR   GO; GO:0004042; F:acetyl-CoA:L-glutamate N-acetyltransferase activity; TAS:BHF-UCL.
DR   GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006536; P:glutamate metabolic process; TAS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
//
ID   NAGT1_HUMAN             Reviewed;         518 AA.
AC   Q5TF39; A8K9M0; Q8IYB6; Q96PW9; Q9P0D6;
DE   RecName: Full=Sodium-dependent glucose transporter 1;
GN   Name=NAGLT1; Synonyms=KIAA1919; ORFNames=HSPC100;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   NAIF1_HUMAN             Reviewed;         327 AA.
AC   Q69YI7; B3KV81; Q8WU12;
DE   RecName: Full=Nuclear apoptosis-inducing factor 1;
GN   Name=NAIF1; Synonyms=C9orf90;
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:1902108; P:regulation of mitochondrial membrane permeability involved in apoptotic process; IDA:UniProtKB.
//
ID   NAKD2_HUMAN             Reviewed;         442 AA.
AC   Q4G0N4; B5MC93; Q6UTX5; Q96NM0;
DE   RecName: Full=NAD kinase 2, mitochondrial;
DE            EC=2.7.1.23;
DE   AltName: Full=Mitochondrial NAD kinase;
DE   AltName: Full=NAD kinase domain-containing protein 1, mitochondrial;
DE   Flags: Precursor;
GN   Name=NADK2; Synonyms=C5orf33, MNADK, NADKD1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003951; F:NAD+ kinase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019674; P:NAD metabolic process; IDA:UniProtKB.
DR   GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
//
ID   NAL10_HUMAN             Reviewed;         655 AA.
AC   Q86W26; Q2M3C4; Q6JGT0;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 10;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 8;
GN   Name=NLRP10; Synonyms=NALP10, NOD8, PYNOD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; ISS:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IMP:UniProtKB.
DR   GO; GO:0036336; P:dendritic cell migration; ISS:UniProtKB.
DR   GO; GO:0035397; P:helper T cell enhancement of adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:2000778; P:positive regulation of interleukin-6 secretion; IMP:UniProtKB.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IMP:UniProtKB.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; ISS:UniProtKB.
DR   GO; GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.
//
ID   NAL11_HUMAN             Reviewed;        1033 AA.
AC   P59045; C9JSF5; Q2TV85; Q2TV86; Q53ZZ0; Q8NBF5;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 11;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 17;
DE   AltName: Full=PAAD-and NACHT domain-containing protein 10;
DE   AltName: Full=PYRIN-containing APAF1-like protein 6;
GN   Name=NLRP11; Synonyms=NALP11, NOD17, PAN10, PYPAF6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016715; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NAL12_HUMAN             Reviewed;        1061 AA.
AC   P59046; A8MTQ2; B3KTE7; Q8NEU4; Q9BY26;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 12;
DE   AltName: Full=Monarch-1;
DE   AltName: Full=PYRIN-containing APAF1-like protein 7;
DE   AltName: Full=Regulated by nitric oxide;
GN   Name=NLRP12; Synonyms=NALP12, PYPAF7, RNO;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IEA:Ensembl.
DR   GO; GO:0036336; P:dendritic cell migration; IEA:Ensembl.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IDA:HGNC.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:HGNC.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0050711; P:negative regulation of interleukin-1 secretion; IDA:HGNC.
DR   GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IDA:HGNC.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:1901223; P:negative regulation of NIK/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0031953; P:negative regulation of protein autophosphorylation; IDA:HGNC.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IDA:HGNC.
DR   GO; GO:0045751; P:negative regulation of Toll signaling pathway; IDA:HGNC.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; NAS:UniProtKB.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; NAS:UniProtKB.
DR   GO; GO:0045381; P:regulation of interleukin-18 biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   NAL14_HUMAN             Reviewed;        1093 AA.
AC   Q86W24; Q7RTR6;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 14;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 5;
GN   Name=NLRP14; Synonyms=NALP14, NOD5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IMP:UniProtKB.
//
ID   NAL13_HUMAN             Reviewed;        1043 AA.
AC   Q86W25; Q7RTR5;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 13;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 14;
GN   Name=NLRP13; Synonyms=NALP13, NOD14;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   NALCN_HUMAN             Reviewed;        1738 AA.
AC   Q8IZF0; Q6P2S6; Q6ZMI7; Q8IZZ1; Q8TAH1;
DE   RecName: Full=Sodium leak channel non-selective protein;
DE   AltName: Full=CanIon;
DE   AltName: Full=Voltage gated channel-like protein 1;
GN   Name=NALCN; Synonyms=VGCNL1;
DR   GuidetoPHARMACOLOGY; 750; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005272; F:sodium channel activity; TAS:Reactome.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0070509; P:calcium ion import; IBA:RefGenome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NALD2_HUMAN             Reviewed;         740 AA.
AC   Q9Y3Q0; B3KQR4; Q4KKV4; Q4VAM9;
DE   RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2;
DE            EC=3.4.17.21;
DE   AltName: Full=Glutamate carboxypeptidase III;
DE            Short=GCPIII;
DE   AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II;
DE            Short=NAALADase II;
GN   Name=NAALAD2;
DR   GO; GO:0004180; F:carboxypeptidase activity; NAS:UniProtKB.
DR   GO; GO:0016805; F:dipeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0050129; F:N-formylglutamate deformylase activity; IEA:Ensembl.
DR   GO; GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   NALDL_HUMAN             Reviewed;         740 AA.
AC   Q9UQQ1; C9J8A1; C9J964; C9JL35; C9JSN0; O43176;
DE   RecName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein;
DE            Short=NAALADase L;
DE            EC=3.4.17.21;
DE   AltName: Full=100 kDa ileum brush border membrane protein;
DE            Short=I100;
DE   AltName: Full=Ileal dipeptidylpeptidase;
GN   Name=NAALADL1; Synonyms=NAALADASEL, NAALADL;
DR   GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; NAS:UniProtKB.
//
ID   NALP2_HUMAN             Reviewed;        1062 AA.
AC   Q9NX02; B4DZL7; I3L0G4; Q53FL5; Q59G09; Q8IXT0; Q9BVN5; Q9H6G6;
AC   Q9HAV9; Q9NWK3;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 2;
DE   AltName: Full=Nucleotide-binding site protein 1;
DE   AltName: Full=PYRIN domain and NACHT domain-containing protein 1;
DE   AltName: Full=PYRIN-containing APAF1-like protein 2;
GN   Name=NLRP2; Synonyms=NALP2, NBS1, PAN1, PYPAF2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032090; F:Pyrin domain binding; IPI:HGNC.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.
//
ID   NALP1_HUMAN             Reviewed;        1473 AA.
AC   Q9C000; E9PE50; I6L9D9; Q9BZZ8; Q9BZZ9; Q9H5Z7; Q9H5Z8; Q9HAV8;
AC   Q9UFT4; Q9Y2E0;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 1;
DE   AltName: Full=Caspase recruitment domain-containing protein 7;
DE   AltName: Full=Death effector filament-forming ced-4-like apoptosis protein;
DE   AltName: Full=Nucleotide-binding domain and caspase recruitment domain;
GN   Name=NLRP1; Synonyms=CARD7, DEFCAP, KIAA0926, NAC, NALP1;
DR   GuidetoPHARMACOLOGY; 1768; -.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0051402; P:neuron apoptotic process; IDA:HGNC.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032495; P:response to muramyl dipeptide; ISS:BHF-UCL.
//
ID   NALP3_HUMAN             Reviewed;        1036 AA.
AC   Q96P20; B2RC97; B7ZKS9; B7ZKT2; B7ZKT3; O75434; Q17RS2; Q59H68;
AC   Q5JQS8; Q5JQS9; Q6TG35; Q8TCW0; Q8TEU9; Q8WXH9;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 3;
DE   AltName: Full=Angiotensin/vasopressin receptor AII/AVP-like;
DE   AltName: Full=Caterpiller protein 1.1;
DE            Short=CLR1.1;
DE   AltName: Full=Cold autoinflammatory syndrome 1 protein;
DE   AltName: Full=Cryopyrin;
DE   AltName: Full=PYRIN-containing APAF1-like protein 1;
GN   Name=NLRP3; Synonyms=C1orf7, CIAS1, NALP3, PYPAF1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042834; F:peptidoglycan binding; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0006952; P:defense response; TAS:HGNC.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0009595; P:detection of biotic stimulus; TAS:HGNC.
DR   GO; GO:0006954; P:inflammatory response; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032611; P:interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0050701; P:interleukin-1 secretion; IEA:Ensembl.
DR   GO; GO:0032621; P:interleukin-18 production; IEA:Ensembl.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0050713; P:negative regulation of interleukin-1 beta secretion; IMP:BHF-UCL.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IDA:HGNC.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:HGNC.
DR   GO; GO:0044546; P:NLRP3 inflammasome complex assembly; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; TAS:HGNC.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   NALP4_HUMAN             Reviewed;         994 AA.
AC   Q96MN2; Q86W87; Q96AY6;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 4;
DE   AltName: Full=Cancer/testis antigen 58;
DE            Short=CT58;
DE   AltName: Full=PAAD and NACHT-containing protein 2;
DE            Short=PAN2;
DE   AltName: Full=PYRIN and NACHT-containing protein 2;
DE   AltName: Full=PYRIN-containing APAF1-like protein 4;
DE            Short=PYPAF4;
DE   AltName: Full=Ribonuclease inhibitor 2;
GN   Name=NLRP4; Synonyms=NALP4, PAN2, PYPAF4, RNH2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
//
ID   NALP5_HUMAN             Reviewed;        1200 AA.
AC   P59047; A8MTY4; Q86W29;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 5;
DE   AltName: Full=Mater protein homolog;
GN   Name=NLRP5; Synonyms=MATER, NALP5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0070997; P:neuron death; IMP:UniProt.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
DR   GO; GO:0043487; P:regulation of RNA stability; IEA:Ensembl.
//
ID   NALP6_HUMAN             Reviewed;         892 AA.
AC   P59044; A8K9F3; E9PJZ8;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 6;
DE   AltName: Full=Angiotensin II/vasopressin receptor;
DE   AltName: Full=PYRIN-containing APAF1-like protein 5;
GN   Name=NLRP6; Synonyms=NALP6, PYPAF5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005000; F:vasopressin receptor activity; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:GOC.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0050777; P:negative regulation of immune response; IEA:Ensembl.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   NALP7_HUMAN             Reviewed;         980 AA.
AC   Q8WX94; E9PE16; Q32MH8; Q7RTR1;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 7;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 12;
DE   AltName: Full=PYRIN-containing APAF1-like protein 3;
GN   Name=NLRP7; Synonyms=NALP7, NOD12, PYPAF3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   NALP8_HUMAN             Reviewed;        1048 AA.
AC   Q86W28; Q7RTR4;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 8;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 16;
DE   AltName: Full=PYRIN and NACHT-containing protein 4;
GN   Name=NLRP8; Synonyms=NALP8, NOD16, PAN4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0070997; P:neuron death; IMP:UniProt.
//
ID   NALP9_HUMAN             Reviewed;         991 AA.
AC   Q7RTR0; B2RN12; Q86W27;
DE   RecName: Full=NACHT, LRR and PYD domains-containing protein 9;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 6;
DE   AltName: Full=PYRIN and NACHT-containing protein 12;
GN   Name=NLRP9; Synonyms=NALP9, NOD6, PAN12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   NAMPT_HUMAN             Reviewed;         491 AA.
AC   P43490; A4D0Q9; A4D0R0; Q3KQV0; Q8WW95;
DE   RecName: Full=Nicotinamide phosphoribosyltransferase;
DE            Short=NAmPRTase;
DE            Short=Nampt;
DE            EC=2.4.2.12;
DE   AltName: Full=Pre-B-cell colony-enhancing factor 1;
DE            Short=Pre-B cell-enhancing factor;
DE   AltName: Full=Visfatin;
GN   Name=NAMPT; Synonyms=PBEF, PBEF1;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0047280; F:nicotinamide phosphoribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0006769; P:nicotinamide metabolic process; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NANG2_HUMAN             Reviewed;         232 AA.
AC   Q8N7R0;
DE   RecName: Full=Putative homeobox protein NANOG2;
GN   Name=NANOGP1; Synonyms=NANOG2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NANGN_HUMAN             Reviewed;         188 AA.
AC   Q7Z5D8;
DE   RecName: Full=NANOG neighbor homeobox;
DE   AltName: Full=Homeobox protein C14;
GN   Name=NANOGNB;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   NANO1_HUMAN             Reviewed;         292 AA.
AC   Q8WY41;
DE   RecName: Full=Nanos homolog 1;
DE            Short=NOS-1;
DE   AltName: Full=EC_Rep1a;
GN   Name=NANOS1; Synonyms=NOS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030371; F:translation repressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0010631; P:epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:GOC.
//
ID   NANO2_HUMAN             Reviewed;         138 AA.
AC   P60321; Q17R30; Q4G0P8;
DE   RecName: Full=Nanos homolog 2;
DE            Short=NOS-2;
GN   Name=NANOS2; Synonyms=NOS2;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045835; P:negative regulation of meiosis; ISS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   NANO3_HUMAN             Reviewed;         173 AA.
AC   P60323; Q495E5;
DE   RecName: Full=Nanos homolog 3;
DE            Short=NOS-3;
GN   Name=NANOS3; Synonyms=NOS3;
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007281; P:germ cell development; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   NANOG_HUMAN             Reviewed;         305 AA.
AC   Q9H9S0; D3DUU4; Q2TTG0; Q6JZS5;
DE   RecName: Full=Homeobox protein NANOG;
DE   AltName: Full=Homeobox transcription factor Nanog;
DE            Short=hNanog;
GN   Name=NANOG;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:HGNC.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEP:HGNC.
DR   GO; GO:0008283; P:cell proliferation; IMP:HGNC.
DR   GO; GO:0009790; P:embryo development; IEP:HGNC.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0001714; P:endodermal cell fate specification; IDA:MGI.
DR   GO; GO:0008406; P:gonad development; IEA:Ensembl.
DR   GO; GO:0001710; P:mesodermal cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0010454; P:negative regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045595; P:regulation of cell differentiation; IMP:HGNC.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IMP:UniProtKB.
DR   GO; GO:0017145; P:stem cell division; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NANP_HUMAN              Reviewed;         248 AA.
AC   Q8TBE9; B3KP12; Q5JYN8; Q8TE97; Q9Y3N0;
DE   RecName: Full=N-acylneuraminate-9-phosphatase;
DE            EC=3.1.3.29;
DE   AltName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 4;
DE   AltName: Full=Neu5Ac-9-Pase;
GN   Name=NANP; Synonyms=C20orf147, HDHD4;
DR   GO; GO:0050124; F:N-acylneuraminate-9-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0006045; P:N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046380; P:N-acetylneuraminate biosynthetic process; IDA:UniProtKB.
//
ID   NANP8_HUMAN             Reviewed;         305 AA.
AC   Q6NSW7;
DE   RecName: Full=Putative homeobox protein NANOGP8;
GN   Name=NANOGP8;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NAP1_HUMAN              Reviewed;         441 AA.
AC   Q9BU70; Q5T113; Q86SK0; Q9NXJ7; Q9P0Q7;
DE   RecName: Full=Nef-associated protein 1;
DE            EC=3.1.2.-;
DE   AltName: Full=Thioesterase NAP1;
GN   Name=C9orf156; Synonyms=NAP1; ORFNames=HSPC219;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NAPEP_HUMAN             Reviewed;         393 AA.
AC   Q6IQ20; Q5CZ87; Q769K1;
DE   RecName: Full=N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D;
DE            Short=N-acyl phosphatidylethanolamine phospholipase D;
DE            Short=NAPE-PLD;
DE            Short=NAPE-hydrolyzing phospholipase D;
DE            EC=3.1.4.54;
GN   Name=NAPEPLD; Synonyms=C7orf18;
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:UniProtKB-KW.
//
ID   NAPSA_HUMAN             Reviewed;         420 AA.
AC   O96009; Q8WWD9;
DE   RecName: Full=Napsin-A;
DE            EC=3.4.23.-;
DE   AltName: Full=Aspartyl protease 4;
DE            Short=ASP4;
DE            Short=Asp 4;
DE   AltName: Full=Napsin-1;
DE   AltName: Full=TA01/TA02;
DE   Flags: Precursor;
GN   Name=NAPSA; Synonyms=NAP1, NAPA;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0043129; P:surfactant homeostasis; IDA:UniProtKB.
//
ID   NAR1_HUMAN              Reviewed;         327 AA.
AC   P52961; Q6NTD2; Q96KT9;
DE   RecName: Full=GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1;
DE            EC=2.4.2.31;
DE   AltName: Full=ADP-ribosyltransferase C2 and C3 toxin-like 1;
DE            Short=ARTC1;
DE   AltName: Full=Mono(ADP-ribosyl)transferase 1;
DE   AltName: CD_antigen=CD296;
DE   Flags: Precursor;
GN   Name=ART1;
DR   GO; GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.
//
ID   NAR3_HUMAN              Reviewed;         389 AA.
AC   Q13508; Q53XW3; Q6FHT7; Q8WVJ7; Q93069; Q96HL1;
DE   RecName: Full=Ecto-ADP-ribosyltransferase 3;
DE            EC=2.4.2.31;
DE   AltName: Full=ADP-ribosyltransferase C2 and C3 toxin-like 3;
DE            Short=ARTC3;
DE   AltName: Full=Mono(ADP-ribosyl)transferase 3;
DE   AltName: Full=NAD(P)(+)--arginine ADP-ribosyltransferase 3;
DE   Flags: Precursor;
GN   Name=ART3; Synonyms=TMART;
DR   GO; GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.
//
ID   NAR4_HUMAN              Reviewed;         314 AA.
AC   Q93070; Q9BZ50; Q9BZ51; Q9HB06;
DE   RecName: Full=Ecto-ADP-ribosyltransferase 4;
DE            EC=2.4.2.31;
DE   AltName: Full=ADP-ribosyltransferase C2 and C3 toxin-like 4;
DE            Short=ARTC4;
DE   AltName: Full=Dombrock blood group carrier molecule;
DE   AltName: Full=Mono(ADP-ribosyl)transferase 4;
DE   AltName: Full=NAD(P)(+)--arginine ADP-ribosyltransferase 4;
DE   AltName: CD_antigen=CD297;
DE   Flags: Precursor;
GN   Name=ART4; Synonyms=DO, DOK1;
DR   GO; GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0006525; P:arginine metabolic process; NAS:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; NAS:UniProtKB.
//
ID   NAR5_HUMAN              Reviewed;         291 AA.
AC   Q96L15; C9IYG7; Q6UX84; Q86W02;
DE   RecName: Full=Ecto-ADP-ribosyltransferase 5;
DE            EC=2.4.2.31;
DE   AltName: Full=ADP-ribosyltransferase C2 and C3 toxin-like 5;
DE            Short=ARTC5;
DE   AltName: Full=Mono(ADP-ribosyl)transferase 5;
DE   AltName: Full=NAD(P)(+)--arginine ADP-ribosyltransferase 5;
DE   Flags: Precursor;
GN   Name=ART5; ORFNames=UNQ575/PRO1137;
DR   GO; GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0003953; F:NAD+ nucleosidase activity; IEA:Ensembl.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IEA:Ensembl.
//
ID   NARFL_HUMAN             Reviewed;         476 AA.
AC   Q9H6Q4; A1L385; B3KTJ3; Q53GC6; Q96S10; Q9H6J8;
DE   RecName: Full=Cytosolic Fe-S cluster assembly factor NARFL;
DE   AltName: Full=Iron-only hydrogenase-like protein 1;
DE            Short=IOP1;
DE   AltName: Full=Nuclear prelamin A recognition factor-like protein;
DE   AltName: Full=Protein related to Narf;
GN   Name=NARFL; Synonyms=PRN;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IMP:UniProtKB.
DR   GO; GO:0032364; P:oxygen homeostasis; IDA:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0001666; P:response to hypoxia; IDA:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NARF_HUMAN              Reviewed;         456 AA.
AC   Q9UHQ1; A6NCJ3; B3KPX2; K4DI98; Q96AY9; Q9BWC6;
DE   RecName: Full=Nuclear prelamin A recognition factor;
DE   AltName: Full=Iron-only hydrogenase-like protein 2;
DE            Short=IOP2;
GN   Name=NARF;
DR   GO; GO:0005521; F:lamin binding; IPI:HGNC.
//
ID   NARG2_HUMAN             Reviewed;         982 AA.
AC   Q659A1; B2RU08; Q05CT1; Q3B7W6; Q63HP4; Q658Q0; Q68CN8; Q6IPW7;
AC   Q6UX23; Q71H65; Q96CY5; Q9HAA2;
DE   RecName: Full=NMDA receptor-regulated protein 2;
GN   Name=NARG2; Synonyms=BRCC1; ORFNames=UNQ3101/PRO10100;
//
ID   NARR_HUMAN              Reviewed;         198 AA.
AC   P0DI83;
DE   RecName: Full=Ras-related protein Rab-34, isoform NARR;
DE   AltName: Full=Nine amino-acid residue-repeats;
GN   Name=RAB34; Synonyms=NARR;
//
ID   NASP_HUMAN              Reviewed;         788 AA.
AC   P49321; A8K6H2; B4DQP3; D3DQ07; F5H3J2; Q53GW5; Q5T622; Q5T625;
AC   Q96A69; Q9BTW2;
DE   RecName: Full=Nuclear autoantigenic sperm protein;
DE            Short=NASP;
GN   Name=NASP;
DR   GO; GO:0051879; F:Hsp90 protein binding; ISS:UniProtKB.
DR   GO; GO:0001824; P:blastocyst development; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; ISS:UniProtKB.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0043486; P:histone exchange; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NAT10_HUMAN             Reviewed;        1025 AA.
AC   Q9H0A0; B4DFD5; E7ESU4; E9PMN9; Q86WK5; Q9C0F4; Q9HA61; Q9NVF2;
DE   RecName: Full=N-acetyltransferase 10;
DE            EC=2.3.1.-;
GN   Name=NAT10; Synonyms=ALP, KIAA1709;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NAT14_HUMAN             Reviewed;         206 AA.
AC   Q8WUY8; Q8TDY7; Q9NS72;
DE   RecName: Full=N-acetyltransferase 14;
DE            EC=2.3.1.-;
DE   AltName: Full=K562 cell-derived leucine-zipper-like protein 1;
GN   Name=NAT14; Synonyms=KLP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   NAT16_HUMAN             Reviewed;         369 AA.
AC   Q8N8M0; Q8NDR1;
DE   RecName: Full=Putative N-acetyltransferase 16;
DE            EC=2.3.1.-;
GN   Name=NAT16; Synonyms=C7orf52;
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
//
ID   NAT6_HUMAN              Reviewed;         286 AA.
AC   Q93015; Q93014;
DE   RecName: Full=N-acetyltransferase 6;
DE            EC=2.3.1.-;
DE   AltName: Full=Protein fusion-2;
DE            Short=Protein fus-2;
GN   Name=NAT6; Synonyms=FUS2;
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
//
ID   NAT8B_HUMAN             Reviewed;         227 AA.
AC   Q9UHF3; Q0VAD9; Q6NT18;
DE   RecName: Full=Probable N-acetyltransferase 8B;
DE            EC=2.3.1.-;
DE   AltName: Full=Camello-like protein 2;
GN   Name=NAT8B; Synonyms=CML2;
DR   GO; GO:0008080; F:N-acetyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
//
ID   NAT8L_HUMAN             Reviewed;         302 AA.
AC   Q8N9F0;
DE   RecName: Full=N-acetylaspartate synthetase;
DE            Short=NAA synthetase;
DE            EC=2.3.1.17;
DE   AltName: Full=Camello-like protein 3;
DE   AltName: Full=N-acetyltransferase 8-like protein;
GN   Name=NAT8L; Synonyms=CML3;
DR   GO; GO:0017188; F:aspartate N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0051586; P:positive regulation of dopamine uptake involved in synaptic transmission; IEA:Ensembl.
//
ID   NAT8_HUMAN              Reviewed;         227 AA.
AC   Q9UHE5; O75839; Q6LEU4; Q96QI8; Q9UQ17;
DE   RecName: Full=Probable N-acetyltransferase 8;
DE            EC=2.3.1.-;
DE   AltName: Full=Camello-like protein 1;
GN   Name=NAT8; Synonyms=CML1, GLA, TSC501;
DR   GO; GO:0008080; F:N-acetyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
//
ID   NAT9_HUMAN              Reviewed;         207 AA.
AC   Q9BTE0; B2R7F0; Q9BTD0; Q9Y3T3;
DE   RecName: Full=N-acetyltransferase 9;
DE            EC=2.3.1.-;
DE   AltName: Full=Embryo brain-specific protein;
GN   Name=NAT9; Synonyms=EBS;
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
//
ID   NAV1_HUMAN              Reviewed;        1877 AA.
AC   Q8NEY1; A8MS88; Q5SVH1; Q5SVH2; Q5SVH3; Q5SVH7; Q5VUY9; Q8IVL2;
AC   Q96II1; Q9H7V9; Q9H9S9; Q9H9T5; Q9UGI1; Q9ULK7; Q9ULR9;
DE   RecName: Full=Neuron navigator 1;
DE   AltName: Full=Pore membrane and/or filament-interacting-like protein 3;
DE   AltName: Full=Steerin-1;
DE   AltName: Full=Unc-53 homolog 1;
DE            Short=unc53H1;
GN   Name=NAV1; Synonyms=KIAA1151, KIAA1213, POMFIL3, STEERIN1;
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
//
ID   NAV2_HUMAN              Reviewed;        2488 AA.
AC   Q8IVL1; A6NEC1; Q8IVK3; Q8IVK4; Q8IVK5; Q8IVK6; Q8IVK7; Q8IVK8;
AC   Q8NHC9; Q8NHD0; Q8TDE9; Q8TDF0; Q8TEB3; Q96B30; Q9NUZ6; Q9NVM7;
AC   Q9P2C8;
DE   RecName: Full=Neuron navigator 2;
DE            EC=3.6.4.12;
DE   AltName: Full=Helicase APC down-regulated 1;
DE   AltName: Full=Pore membrane and/or filament-interacting-like protein 2;
DE   AltName: Full=Retinoic acid inducible in neuroblastoma 1;
DE   AltName: Full=Steerin-2;
DE   AltName: Full=Unc-53 homolog 2;
DE            Short=unc53H2;
GN   Name=NAV2; Synonyms=HELAD1, KIAA1419, POMFIL2, RAINB1, STEERIN2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0021563; P:glossopharyngeal nerve development; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0021554; P:optic nerve development; IEA:Ensembl.
DR   GO; GO:0003025; P:regulation of systemic arterial blood pressure by baroreceptor feedback; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0021564; P:vagus nerve development; IEA:Ensembl.
//
ID   NAV3_HUMAN              Reviewed;        2385 AA.
AC   Q8IVL0; Q8NFW7; Q9Y2E7;
DE   RecName: Full=Neuron navigator 3;
DE   AltName: Full=Pore membrane and/or filament-interacting-like protein 1;
DE   AltName: Full=Steerin-3;
DE   AltName: Full=Unc-53 homolog 3;
DE            Short=unc53H3;
GN   Name=NAV3; Synonyms=KIAA0938, POMFIL1, STEERIN3;
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   NB5R1_HUMAN             Reviewed;         305 AA.
AC   Q9UHQ9; A0PK21; B2R8E0; O95329; Q53F73; Q8NCL5; Q9UHJ1;
DE   RecName: Full=NADH-cytochrome b5 reductase 1;
DE            Short=b5R.1;
DE            EC=1.6.2.2;
DE   AltName: Full=Humb5R2;
DE   AltName: Full=NAD(P)H:quinone oxidoreductase type 3 polypeptide A2;
GN   Name=CYB5R1; Synonyms=NQO3A2; ORFNames=UNQ3049/PRO9865;
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; IEA:UniProtKB-EC.
DR   GO; GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
//
ID   NB5R2_HUMAN             Reviewed;         276 AA.
AC   Q6BCY4; Q9BVA3; Q9UF68; Q9UHJ0;
DE   RecName: Full=NADH-cytochrome b5 reductase 2;
DE            Short=b5R.2;
DE            EC=1.6.2.2;
GN   Name=CYB5R2;
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
//
ID   NB5R3_HUMAN             Reviewed;         301 AA.
AC   P00387; B1AHF2; B7Z7L3; O75675; Q8TDL8; Q8WTS8; Q9UEN4; Q9UEN5;
AC   Q9UL55; Q9UL56;
DE   RecName: Full=NADH-cytochrome b5 reductase 3;
DE            Short=B5R;
DE            Short=Cytochrome b5 reductase;
DE            EC=1.6.2.2;
DE   AltName: Full=Diaphorase-1;
DE   Contains:
DE     RecName: Full=NADH-cytochrome b5 reductase 3 membrane-bound form;
DE   Contains:
DE     RecName: Full=NADH-cytochrome b5 reductase 3 soluble form;
GN   Name=CYB5R3; Synonyms=DIA1;
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0016208; F:AMP binding; IEA:Ensembl.
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; TAS:Reactome.
DR   GO; GO:0071949; F:FAD binding; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NB5R4_HUMAN             Reviewed;         521 AA.
AC   Q7L1T6; B1AEM2; Q5TGI9; Q9NUE4; Q9UHI9;
DE   RecName: Full=Cytochrome b5 reductase 4;
DE            EC=1.6.2.2;
DE   AltName: Full=Flavohemoprotein b5/b5R;
DE            Short=b5+b5R;
DE   AltName: Full=N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein;
DE   AltName: Full=cb5/cb5R;
GN   Name=CYB5R4; Synonyms=NCB5OR;
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; IDA:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016174; F:NAD(P)H oxidase activity; IDA:UniProtKB.
DR   GO; GO:0003958; F:NADPH-hemoprotein reductase activity; IEA:Ensembl.
DR   GO; GO:0016653; F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor; IDA:UniProtKB.
DR   GO; GO:0048468; P:cell development; ISS:UniProtKB.
DR   GO; GO:0003032; P:detection of oxygen; NAS:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0030073; P:insulin secretion; ISS:UniProtKB.
DR   GO; GO:0006739; P:NADP metabolic process; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; ISS:UniProtKB.
DR   GO; GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
//
ID   NB5R5_HUMAN             Reviewed;         315 AA.
AC   Q6IPT4; B7ZBS4; Q8NF25;
DE   RecName: Full=NADH-cytochrome b5 reductase-like;
DE            EC=1.6.2.2;
GN   Name=CYB5RL;
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; IEA:UniProtKB-EC.
//
ID   NBAS_HUMAN              Reviewed;        2371 AA.
AC   A2RRP1; O95790; Q2VPJ7; Q53TK6; Q86V39; Q8NFY8; Q9Y3W5;
DE   RecName: Full=Neuroblastoma-amplified sequence;
DE   AltName: Full=Neuroblastoma-amplified gene protein;
GN   Name=NBAS; Synonyms=NAG;
DR   GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProt.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProt.
//
ID   NBEA_HUMAN              Reviewed;        2946 AA.
AC   Q8NFP9; B7Z2H9; Q5T320; Q9HCM8; Q9NSU1; Q9NW98; Q9Y6J1;
DE   RecName: Full=Neurobeachin;
DE   AltName: Full=Lysosomal-trafficking regulator 2;
DE   AltName: Full=Protein BCL8B;
GN   Name=NBEA; Synonyms=BCL8B, KIAA1544, LYST2;
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
//
ID   NBEL1_HUMAN             Reviewed;        2694 AA.
AC   Q6ZS30; A6NHD5; Q6Y876; Q6ZP36; Q6ZQY5; Q8N8R4; Q96Q30; Q96Q31;
DE   RecName: Full=Neurobeachin-like protein 1;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein;
GN   Name=NBEAL1; Synonyms=ALS2CR16, ALS2CR17;
//
ID   NBEL2_HUMAN             Reviewed;        2754 AA.
AC   Q6ZNJ1; O60288; Q6P994; Q6UX91; Q8NAC9;
DE   RecName: Full=Neurobeachin-like protein 2;
GN   Name=NBEAL2; Synonyms=KIAA0540; ORFNames=UNQ253/PRO290;
DR   GO; GO:0030220; P:platelet formation; IMP:UniProtKB.
//
ID   NBL1_HUMAN              Reviewed;         181 AA.
AC   P41271; A3KFI7; Q5TGZ2; Q5U0N4; Q96L68;
DE   RecName: Full=Neuroblastoma suppressor of tumorigenicity 1;
DE   AltName: Full=DAN domain family member 1;
DE   AltName: Full=Protein N03;
DE   AltName: Full=Zinc finger protein DAN;
DE   Flags: Precursor;
GN   Name=NBL1; Synonyms=DAN, DAND1;
DR   GO; GO:0036122; F:BMP binding; ISS:BHF-UCL.
DR   GO; GO:0016015; F:morphogen activity; ISS:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IMP:UniProt.
DR   GO; GO:0048263; P:determination of dorsal identity; ISS:BHF-UCL.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProt.
DR   GO; GO:0090027; P:negative regulation of monocyte chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; ISS:BHF-UCL.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0038098; P:sequestering of BMP from receptor via BMP binding; IDA:UniProt.
DR   GO; GO:0035582; P:sequestering of BMP in extracellular matrix; ISS:BHF-UCL.
//
ID   NBN_HUMAN               Reviewed;         754 AA.
AC   O60934; B2R626; B2RNC5; O60672; Q32NF7; Q53FM6; Q63HR6; Q7LDM2;
DE   RecName: Full=Nibrin;
DE   AltName: Full=Cell cycle regulatory protein p95;
DE   AltName: Full=Nijmegen breakage syndrome protein 1;
GN   Name=NBN; Synonyms=NBS, NBS1, P95;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0001832; P:blastocyst growth; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0000077; P:DNA damage checkpoint; IDA:MGI.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; TAS:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IMP:BHF-UCL.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:UniProtKB.
DR   GO; GO:0007095; P:mitotic G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IDA:BHF-UCL.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0030174; P:regulation of DNA-dependent DNA replication initiation; TAS:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
//
ID   NBP6L_HUMAN             Reviewed;         240 AA.
AC   A8MWS5;
DE   RecName: Full=Putative neuroblastoma breakpoint family member 6-like protein;
//
ID   NBPF1_HUMAN             Reviewed;        1214 AA.
AC   Q3BBV0; Q8N4E8; Q9C0H0;
DE   RecName: Full=Neuroblastoma breakpoint family member 1;
GN   Name=NBPF1; Synonyms=KIAA1693;
//
ID   NBPF3_HUMAN             Reviewed;         633 AA.
AC   Q9H094; A8K965; B4DSP2; I3L0I8; Q3BBW1; Q5VTG2; Q5VTG3; Q5VTG4;
AC   Q8IX78; Q8ND86; Q8TC96;
DE   RecName: Full=Neuroblastoma breakpoint family member 3;
DE   AltName: Full=Protein AE2;
DE   AltName: Full=Protein SHIIIa4;
GN   Name=NBPF3; ORFNames=L7;
//
ID   NBPF4_HUMAN             Reviewed;         638 AA.
AC   Q96M43; Q5T483;
DE   RecName: Full=Neuroblastoma breakpoint family member 4;
GN   Name=NBPF4;
//
ID   NBPF6_HUMAN             Reviewed;         638 AA.
AC   Q5VWK0; A4QN25;
DE   RecName: Full=Neuroblastoma breakpoint family member 6;
GN   Name=NBPF6;
//
ID   NBPF5_HUMAN             Reviewed;         351 AA.
AC   Q86XG9;
DE   RecName: Full=Putative neuroblastoma breakpoint family member 5;
GN   Name=NBPF5P; Synonyms=NBPF5;
//
ID   NBPF7_HUMAN             Reviewed;         421 AA.
AC   P0C2Y1;
DE   RecName: Full=Putative neuroblastoma breakpoint family member 7;
GN   Name=NBPF7;
//
ID   NBPF9_HUMAN             Reviewed;         867 AA.
AC   Q3BBW0;
DE   RecName: Full=Neuroblastoma breakpoint family member 9;
GN   Name=NBPF9;
//
ID   NBPF8_HUMAN             Reviewed;         869 AA.
AC   Q3BBV2;
DE   RecName: Full=Putative neuroblastoma breakpoint family member 8;
GN   Name=NBPF8; Synonyms=NBPF8P;
//
ID   NBPFA_HUMAN             Reviewed;         841 AA.
AC   Q6P3W6; Q5RHC0; Q9NWN6;
DE   RecName: Full=Neuroblastoma breakpoint family member 10;
GN   Name=NBPF10;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NBPFC_HUMAN             Reviewed;         269 AA.
AC   Q5TAG4; O95877;
DE   RecName: Full=Neuroblastoma breakpoint family member 12;
DE   AltName: Full=Chromosome 1 amplified sequence 1;
GN   Name=NBPF12; Synonyms=COAS1, KIAA1245;
//
ID   NBPFB_HUMAN             Reviewed;         865 AA.
AC   Q86T75; B1AKG1; B7Z7R4;
DE   RecName: Full=Neuroblastoma breakpoint family member 11;
GN   Name=NBPF11;
//
ID   NBPFE_HUMAN             Reviewed;         921 AA.
AC   Q5TI25; Q5TI23; Q8IX76; Q9UJI9;
DE   RecName: Full=Neuroblastoma breakpoint family member 14;
GN   Name=NBPF14;
//
ID   NBPFG_HUMAN             Reviewed;         670 AA.
AC   Q5SXJ2; A8MPT6;
DE   RecName: Full=Neuroblastoma breakpoint family member 16;
GN   Name=NBPF16;
//
ID   NBPFF_HUMAN             Reviewed;         670 AA.
AC   Q8N660; Q3BBV9; Q8IX77;
DE   RecName: Full=Neuroblastoma breakpoint family member 15;
GN   Name=NBPF15;
//
ID   NBPFP_HUMAN             Reviewed;         902 AA.
AC   B4DH59;
DE   RecName: Full=Neuroblastoma breakpoint family member 26;
GN   Name=NBPF26;
//
ID   NBPFN_HUMAN             Reviewed;         790 AA.
AC   Q5RGN0;
DE   RecName: Full=Putative neuroblastoma breakpoint family member 24;
GN   Name=NBPF24;
//
ID   NBPFL_HUMAN             Reviewed;         598 AA.
AC   A6NDD8;
DE   RecName: Full=Neuroblastoma breakpoint family member 21;
GN   Name=NBPF21;
//
ID   NBPFK_HUMAN             Reviewed;         942 AA.
AC   Q3BBV1;
DE   RecName: Full=Neuroblastoma breakpoint family member 20;
GN   Name=NBPF20;
//
ID   NBR1_HUMAN              Reviewed;         966 AA.
AC   Q14596; Q13173; Q15026; Q5J7Q8; Q96GB6; Q9NRF7;
DE   RecName: Full=Next to BRCA1 gene 1 protein;
DE   AltName: Full=Cell migration-inducing gene 19 protein;
DE   AltName: Full=Membrane component chromosome 17 surface marker 2;
DE   AltName: Full=Neighbor of BRCA1 gene 1 protein;
DE   AltName: Full=Protein 1A1-3B;
GN   Name=NBR1; Synonyms=1A13B, KIAA0049, M17S2; ORFNames=MIG19;
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016236; P:macroautophagy; IDA:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0030500; P:regulation of bone mineralization; ISS:BHF-UCL.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; ISS:BHF-UCL.
//
ID   NBR2_HUMAN              Reviewed;         112 AA.
AC   O15453; Q3LRJ7;
DE   RecName: Full=Next to BRCA1 gene 2 protein;
DE   AltName: Full=Neighbor of BRCA1 gene 2 protein;
GN   Name=NBR2;
//
ID   NC2A_HUMAN              Reviewed;         205 AA.
AC   Q14919; Q13448;
DE   RecName: Full=Dr1-associated corepressor;
DE   AltName: Full=Dr1-associated protein 1;
DE   AltName: Full=Negative cofactor 2-alpha;
DE            Short=NC2-alpha;
GN   Name=DRAP1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NC2B_HUMAN              Reviewed;         176 AA.
AC   Q01658;
DE   RecName: Full=Protein Dr1;
DE   AltName: Full=Down-regulator of transcription 1;
DE   AltName: Full=Negative cofactor 2-beta;
DE            Short=NC2-beta;
DE   AltName: Full=TATA-binding protein-associated phosphoprotein;
GN   Name=DR1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0017025; F:TBP-class protein binding; IDA:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NC336_HUMAN             Reviewed;         198 AA.
AC   Q6ZUF6;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00336;
GN   Name=LINC00336; Synonyms=C6orf227, NCRNA00336;
//
ID   NC301_HUMAN             Reviewed;          95 AA.
AC   Q8NCQ3;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00301;
GN   Name=LINC00301; Synonyms=C11orf64, NCRNA00301;
//
ID   NCALD_HUMAN             Reviewed;         193 AA.
AC   P61601; P29554; Q8IYC3; Q9H0W2;
DE   RecName: Full=Neurocalcin-delta;
GN   Name=NCALD;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0003073; P:regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
//
ID   NCAM1_HUMAN             Reviewed;         858 AA.
AC   P13591; A8K8T8; P13592; P13593; Q05C58; Q15829; Q16180; Q16209;
AC   Q59FL7; Q86X47; Q96CJ3;
DE   RecName: Full=Neural cell adhesion molecule 1;
DE            Short=N-CAM-1;
DE            Short=NCAM-1;
DE   AltName: CD_antigen=CD56;
DE   Flags: Precursor;
GN   Name=NCAM1; Synonyms=NCAM;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
//
ID   NCAM2_HUMAN             Reviewed;         837 AA.
AC   O15394; A8MQ06; Q7Z7F2;
DE   RecName: Full=Neural cell adhesion molecule 2;
DE            Short=N-CAM-2;
DE            Short=NCAM-2;
DE   Flags: Precursor;
GN   Name=NCAM2; Synonyms=NCAM21;
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:ProtInc.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
//
ID   NCAN_HUMAN              Reviewed;        1321 AA.
AC   O14594; Q9UPK6;
DE   RecName: Full=Neurocan core protein;
DE   AltName: Full=Chondroitin sulfate proteoglycan 3;
DE   Flags: Precursor;
GN   Name=NCAN; Synonyms=CSPG3, NEUR;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0051823; P:regulation of synapse structural plasticity; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NCAS2_HUMAN             Reviewed;          99 AA.
AC   Q69YL0;
DE   RecName: Full=Uncharacterized protein NCBP2-AS2;
DE   AltName: Full=NCBP2 antisense RNA 2;
DE   AltName: Full=NCBP2 antisense gene protein 2;
GN   Name=NCBP2-AS2;
//
ID   NCB2L_HUMAN             Reviewed;         153 AA.
AC   A6PVI3;
DE   RecName: Full=Nuclear cap-binding protein subunit 2-like;
GN   Name=NCBP2L;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0000339; F:RNA cap binding; IEA:InterPro.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
//
ID   NCBP1_HUMAN             Reviewed;         790 AA.
AC   Q09161; B2R718; Q59G76; Q5T1V0; Q5T7X2;
DE   RecName: Full=Nuclear cap-binding protein subunit 1;
DE   AltName: Full=80 kDa nuclear cap-binding protein;
DE            Short=CBP80;
DE            Short=NCBP 80 kDa subunit;
GN   Name=NCBP1; Synonyms=CBP80, NCBP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0000339; F:RNA cap binding; TAS:ProtInc.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:InterPro.
DR   GO; GO:0006379; P:mRNA cleavage; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0031442; P:positive regulation of mRNA 3'-end processing; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NCBP2_HUMAN             Reviewed;         156 AA.
AC   P52298; B2RE91; B4DMK7; E9PAR5; Q14924; Q2TS50;
DE   RecName: Full=Nuclear cap-binding protein subunit 2;
DE   AltName: Full=20 kDa nuclear cap-binding protein;
DE   AltName: Full=Cell proliferation-inducing gene 55 protein;
DE   AltName: Full=NCBP 20 kDa subunit;
DE            Short=CBP20;
DE   AltName: Full=NCBP-interacting protein 1;
DE            Short=NIP1;
GN   Name=NCBP2; Synonyms=CBP20; ORFNames=PIG55;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000340; F:RNA 7-methylguanosine cap binding; IDA:UniProtKB.
DR   GO; GO:0000339; F:RNA cap binding; NAS:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0046833; P:positive regulation of RNA export from nucleus; ISS:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; ISS:UniProtKB.
DR   GO; GO:0006408; P:snRNA export from nucleus; ISS:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NCDN_HUMAN              Reviewed;         729 AA.
AC   Q9UBB6; D3DPR9; Q9UBY2; Q9Y4A6; Q9Y4D9;
DE   RecName: Full=Neurochondrin;
GN   Name=NCDN; Synonyms=KIAA0607;
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
//
ID   NCEH1_HUMAN             Reviewed;         408 AA.
AC   Q6PIU2; B7Z2K4; B7Z3A1; B7Z5U2; B7Z906; B7ZAW6; F5H7K4; Q86WZ1;
AC   Q9P2I4;
DE   RecName: Full=Neutral cholesterol ester hydrolase 1;
DE            Short=NCEH;
DE            EC=3.1.1.-;
DE   AltName: Full=Arylacetamide deacetylase-like 1;
GN   Name=NCEH1; Synonyms=AADACL1, KIAA1363;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   NCF1C_HUMAN             Reviewed;         366 AA.
AC   A8MVU1;
DE   RecName: Full=Putative neutrophil cytosol factor 1C;
DE            Short=NCF-1C;
DE   AltName: Full=Putative SH3 and PX domain-containing protein 1C;
GN   Name=NCF1C; Synonyms=SH3PXD1C;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro.
//
ID   NCF1_HUMAN              Reviewed;         390 AA.
AC   P14598; A6NEH2; A8K7S9; O43842; Q2PP07; Q53FR5; Q9BU90; Q9BXI7;
AC   Q9BXI8; Q9UDV9; Q9UMU2;
DE   RecName: Full=Neutrophil cytosol factor 1;
DE            Short=NCF-1;
DE   AltName: Full=47 kDa autosomal chronic granulomatous disease protein;
DE   AltName: Full=47 kDa neutrophil oxidase factor;
DE   AltName: Full=NCF-47K;
DE   AltName: Full=Neutrophil NADPH oxidase factor 1;
DE   AltName: Full=Nox organizer 2;
DE   AltName: Full=Nox-organizing protein 2;
DE   AltName: Full=SH3 and PX domain-containing protein 1A;
DE   AltName: Full=p47-phox;
GN   Name=NCF1; Synonyms=NOXO2, SH3PXD1A;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IMP:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0006691; P:leukotriene metabolic process; IEA:Ensembl.
DR   GO; GO:0045986; P:negative regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0070947; P:neutrophil mediated killing of fungus; IEA:Ensembl.
DR   GO; GO:0070946; P:neutrophil mediated killing of gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IMP:GOC.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.
DR   GO; GO:0045730; P:respiratory burst; TAS:BHF-UCL.
DR   GO; GO:0002679; P:respiratory burst involved in defense response; IEA:Ensembl.
DR   GO; GO:0001878; P:response to yeast; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; IMP:UniProtKB.
DR   GO; GO:0006801; P:superoxide metabolic process; TAS:BHF-UCL.
//
ID   NCF1B_HUMAN             Reviewed;         391 AA.
AC   A6NI72;
DE   RecName: Full=Putative neutrophil cytosol factor 1B;
DE            Short=NCF-1B;
DE   AltName: Full=Putative SH3 and PX domain-containing protein 1B;
GN   Name=NCF1B; Synonyms=SH3PXD1B;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro.
//
ID   NCF2_HUMAN              Reviewed;         526 AA.
AC   P19878; B2R6Q1; B4DKQ7; B4DQA7; E9PHJ2; E9PHX3; Q2PP06; Q8NFC7;
AC   Q9BV51;
DE   RecName: Full=Neutrophil cytosol factor 2;
DE            Short=NCF-2;
DE   AltName: Full=67 kDa neutrophil oxidase factor;
DE   AltName: Full=NADPH oxidase activator 2;
DE   AltName: Full=Neutrophil NADPH oxidase factor 2;
DE   AltName: Full=p67-phox;
GN   Name=NCF2; Synonyms=NOXA2, P67PHOX;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045730; P:respiratory burst; TAS:BHF-UCL.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; TAS:BHF-UCL.
DR   GO; GO:0006801; P:superoxide metabolic process; TAS:BHF-UCL.
//
ID   NCF4_HUMAN              Reviewed;         339 AA.
AC   Q15080; A8K4F9; O60808; Q86U56; Q9BU98; Q9NP45;
DE   RecName: Full=Neutrophil cytosol factor 4;
DE            Short=NCF-4;
DE   AltName: Full=Neutrophil NADPH oxidase factor 4;
DE   AltName: Full=SH3 and PX domain-containing protein 4;
DE   AltName: Full=p40-phox;
DE            Short=p40phox;
GN   Name=NCF4; Synonyms=SH3PXD4;
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
DR   GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IMP:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IMP:GOC.
//
ID   NCK1_HUMAN              Reviewed;         377 AA.
AC   P16333; B7Z751; D3DNE3;
DE   RecName: Full=Cytoplasmic protein NCK1;
DE   AltName: Full=NCK adaptor protein 1;
DE            Short=Nck-1;
DE   AltName: Full=SH2/SH3 adaptor protein NCK-alpha;
GN   Name=NCK1; Synonyms=NCK;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:Ensembl.
DR   GO; GO:0007172; P:signal complex assembly; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; IMP:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   NCK5L_HUMAN             Reviewed;        1330 AA.
AC   Q9HCH0; Q2TB26; Q71RH1; Q8N4W1; Q96HX2;
DE   RecName: Full=Nck-associated protein 5-like;
DE            Short=NCKAP5-like;
GN   Name=NCKAP5L; Synonyms=KIAA1602; ORFNames=FP1193;
//
ID   NCK2_HUMAN              Reviewed;         380 AA.
AC   O43639; D3DVK1; Q9BWN9; Q9UIC3;
DE   RecName: Full=Cytoplasmic protein NCK2;
DE   AltName: Full=Growth factor receptor-bound protein 4;
DE   AltName: Full=NCK adaptor protein 2;
DE            Short=Nck-2;
DE   AltName: Full=SH2/SH3 adaptor protein NCK-beta;
GN   Name=NCK2; Synonyms=GRB4;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007172; P:signal complex assembly; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
//
ID   NCKP1_HUMAN             Reviewed;        1128 AA.
AC   Q9Y2A7; O60329; Q53QN5; Q53S94; Q53Y35;
DE   RecName: Full=Nck-associated protein 1;
DE            Short=NAP 1;
DE   AltName: Full=Membrane-associated protein HEM-2;
DE   AltName: Full=p125Nap1;
GN   Name=NCKAP1; Synonyms=HEM2, KIAA0587, NAP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0045176; P:apical protein localization; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0045175; P:basal protein localization; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0010172; P:embryonic body morphogenesis; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0035050; P:embryonic heart tube development; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0008078; P:mesodermal cell migration; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0048570; P:notochord morphogenesis; IEA:Ensembl.
DR   GO; GO:0048340; P:paraxial mesoderm morphogenesis; IEA:Ensembl.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IDA:UniProt.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IMP:UniProt.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:0016601; P:Rac protein signal transduction; IDA:UniProt.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0007354; P:zygotic determination of anterior/posterior axis, embryo; IEA:Ensembl.
//
ID   NCKP5_HUMAN             Reviewed;        1909 AA.
AC   O14513; B8ZZL0; Q29SS9; Q29ST0; Q2NL90; Q6ZVE2; Q8NAS3;
DE   RecName: Full=Nck-associated protein 5;
DE            Short=NAP-5;
DE   AltName: Full=Peripheral clock protein;
GN   Name=NCKAP5; Synonyms=ERIH, NAP5;
//
ID   NCKPL_HUMAN             Reviewed;        1127 AA.
AC   P55160; B4DUT5; Q52LW0;
DE   RecName: Full=Nck-associated protein 1-like;
DE   AltName: Full=Hematopoietic protein 1;
DE   AltName: Full=Membrane-associated protein HEM-1;
GN   Name=NCKAP1L; Synonyms=HEM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IMP:UniProtKB.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IMP:UniProtKB.
DR   GO; GO:0070358; P:actin polymerization-dependent cell motility; IMP:UniProtKB.
DR   GO; GO:0001782; P:B cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0048821; P:erythrocyte development; IEP:UniProtKB.
DR   GO; GO:0030011; P:maintenance of cell polarity; IMP:UniProtKB.
DR   GO; GO:0002262; P:myeloid cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; ISS:UniProtKB.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; ISS:UniProtKB.
DR   GO; GO:0035509; P:negative regulation of myosin-light-chain-phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043378; P:positive regulation of CD8-positive, alpha-beta T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045621; P:positive regulation of lymphocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:UniProtKB.
DR   GO; GO:0060100; P:positive regulation of phagocytosis, engulfment; ISS:UniProtKB.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:GOC.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IMP:GOC.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; ISS:UniProtKB.
//
ID   NCKX1_HUMAN             Reviewed;        1099 AA.
AC   O60721; O43485; O75184; Q17RM9;
DE   RecName: Full=Sodium/potassium/calcium exchanger 1;
DE   AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 1;
DE   AltName: Full=Retinal rod Na-Ca+K exchanger;
DE   AltName: Full=Solute carrier family 24 member 1;
GN   Name=SLC24A1; Synonyms=KIAA0702, NCKX1;
DR   GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0009642; P:response to light intensity; NAS:UniProtKB.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
//
ID   NCKX2_HUMAN             Reviewed;         661 AA.
AC   Q9UI40; B7ZLL8; Q9NTN5; Q9NZQ4;
DE   RecName: Full=Sodium/potassium/calcium exchanger 2;
DE   AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 2;
DE   AltName: Full=Retinal cone Na-Ca+K exchanger;
DE   AltName: Full=Solute carrier family 24 member 2;
GN   Name=SLC24A2; Synonyms=NCKX2;
DR   GO; GO:0046870; F:cadmium ion binding; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:MGI.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0016151; F:nickel cation binding; IEA:Ensembl.
DR   GO; GO:0030955; F:potassium ion binding; IEA:Ensembl.
DR   GO; GO:0031402; F:sodium ion binding; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IDA:MGI.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   NCKX3_HUMAN             Reviewed;         644 AA.
AC   Q9HC58; B1AKV7; Q9BQJ9; Q9BQL7; Q9BQY3; Q9H519;
DE   RecName: Full=Sodium/potassium/calcium exchanger 3;
DE   AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 3;
DE   AltName: Full=Solute carrier family 24 member 3;
DE   Flags: Precursor;
GN   Name=SLC24A3; Synonyms=NCKX3;
DR   GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NCKX4_HUMAN             Reviewed;         622 AA.
AC   Q8NFF2; B4DHE7; B9ZVY2; Q8N8U6; Q8NCX1; Q8NFF0; Q8NFF1;
DE   RecName: Full=Sodium/potassium/calcium exchanger 4;
DE   AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 4;
DE   AltName: Full=Solute carrier family 24 member 4;
DE   Flags: Precursor;
GN   Name=SLC24A4; Synonyms=NCKX4;
DR   GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0097186; P:amelogenesis; ISS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NCKX5_HUMAN             Reviewed;         500 AA.
AC   Q71RS6; A5X8Z8; A5X8Z9; Q14CT4; Q6DKH3;
DE   RecName: Full=Sodium/potassium/calcium exchanger 5;
DE   AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 5;
DE   AltName: Full=Solute carrier family 24 member 5;
DE   Flags: Precursor;
GN   Name=SLC24A5; Synonyms=JSX, NCKX5;
DR   GO; GO:0008273; F:calcium, potassium:sodium antiporter activity; IDA:MGI.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IDA:MGI.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NCKX6_HUMAN             Reviewed;         584 AA.
AC   Q6J4K2; A6NP50; Q4KMS9; Q6J4K1; Q9H6I8;
DE   RecName: Full=Sodium/potassium/calcium exchanger 6, mitochondrial;
DE   AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 6;
DE   AltName: Full=Sodium/calcium exchanger protein, mitochondrial;
DE   AltName: Full=Solute carrier family 24 member 6;
DE   AltName: Full=Solute carrier family 8 member B1;
DE   Flags: Precursor;
GN   Name=SLC8B1; Synonyms=NCKX6, NCLX, SLC24A6;
DR   GO; GO:0005432; F:calcium:sodium antiporter activity; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; IDA:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NCOA5_HUMAN             Reviewed;         579 AA.
AC   Q9HCD5; B2RTV9; E1P5R0; Q6HA99; Q9H1F2; Q9H2T2; Q9H4Y9;
DE   RecName: Full=Nuclear receptor coactivator 5;
DE            Short=NCoA-5;
DE   AltName: Full=Coactivator independent of AF-2;
DE            Short=CIA;
GN   Name=NCOA5; Synonyms=KIAA1637;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NCOA4_HUMAN             Reviewed;         614 AA.
AC   Q13772; A8K8W5; B4E260; E9PAV7; J3KQN8; Q14239;
DE   RecName: Full=Nuclear receptor coactivator 4;
DE            Short=NCoA-4;
DE   AltName: Full=Androgen receptor coactivator 70 kDa protein;
DE            Short=70 kDa AR-activator;
DE            Short=70 kDa androgen receptor coactivator;
DE   AltName: Full=Androgen receptor-associated protein of 70 kDa;
DE   AltName: Full=Ret-activating protein ELE1;
GN   Name=NCOA4; Synonyms=ARA70, ELE1, RFG;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NCMAP_HUMAN             Reviewed;         102 AA.
AC   Q5T1S8; A0PK04; B2RV34;
DE   RecName: Full=Noncompact myelin-associated protein;
DE   AltName: Full=Myelin protein of 11 kDa;
DE            Short=MP11;
GN   Name=NCMAP; Synonyms=C1orf130;
DR   GO; GO:0019911; F:structural constituent of myelin sheath; ISS:UniProtKB.
DR   GO; GO:0032290; P:peripheral nervous system myelin formation; ISS:UniProtKB.
DR   GO; GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.
//
ID   NCOA3_HUMAN             Reviewed;        1424 AA.
AC   Q9Y6Q9; A4LAZ5; Q0VF45; Q5JYD9; Q5JYE0; Q9BR49; Q9UPC9; Q9UPG4;
AC   Q9UPG7;
DE   RecName: Full=Nuclear receptor coactivator 3;
DE            Short=NCoA-3;
DE            EC=2.3.1.48;
DE   AltName: Full=ACTR;
DE   AltName: Full=Amplified in breast cancer 1 protein;
DE            Short=AIB-1;
DE   AltName: Full=CBP-interacting protein;
DE            Short=pCIP;
DE   AltName: Full=Class E basic helix-loop-helix protein 42;
DE            Short=bHLHe42;
DE   AltName: Full=Receptor-associated coactivator 3;
DE            Short=RAC-3;
DE   AltName: Full=Steroid receptor coactivator protein 3;
DE            Short=SRC-3;
DE   AltName: Full=Thyroid hormone receptor activator molecule 1;
DE            Short=TRAM-1;
GN   Name=NCOA3; Synonyms=AIB1, BHLHE42, RAC3, TRAM1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IEA:InterPro.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0016573; P:histone acetylation; IDA:GOC.
DR   GO; GO:0060713; P:labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0060744; P:mammary gland branching involved in thelarche; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0035624; P:receptor transactivation; TAS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   NCOA1_HUMAN             Reviewed;        1441 AA.
AC   Q15788; O00150; O43792; O43793; Q13071; Q13420; Q2T9G5; Q53SX3;
AC   Q6GVI5; Q7KYV3;
DE   RecName: Full=Nuclear receptor coactivator 1;
DE            Short=NCoA-1;
DE            EC=2.3.1.48;
DE   AltName: Full=Class E basic helix-loop-helix protein 74;
DE            Short=bHLHe74;
DE   AltName: Full=Protein Hin-2;
DE   AltName: Full=RIP160;
DE   AltName: Full=Renal carcinoma antigen NY-REN-52;
DE   AltName: Full=Steroid receptor coactivator 1;
DE            Short=SRC-1;
GN   Name=NCOA1; Synonyms=BHLHE74, SRC1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0001012; F:RNA polymerase II regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0060206; P:estrous cycle phase; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0043967; P:histone H4 acetylation; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0060713; P:labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0060179; P:male mating behavior; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045925; P:positive regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000435; P:positive regulation of transcription from RNA polymerase II promoter by galactose; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:2001038; P:regulation of cellular response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   NCOA6_HUMAN             Reviewed;        2063 AA.
AC   Q14686; A6NLF1; B2RMN5; E1P5P7; Q9NTZ9; Q9UH74; Q9UK86;
DE   RecName: Full=Nuclear receptor coactivator 6;
DE   AltName: Full=Activating signal cointegrator 2;
DE            Short=ASC-2;
DE   AltName: Full=Amplified in breast cancer protein 3;
DE   AltName: Full=Cancer-amplified transcriptional coactivator ASC-2;
DE   AltName: Full=Nuclear receptor coactivator RAP250;
DE            Short=NRC RAP250;
DE   AltName: Full=Nuclear receptor-activating protein, 250 kDa;
DE   AltName: Full=Peroxisome proliferator-activated receptor-interacting protein;
DE            Short=PPAR-interacting protein;
DE            Short=PRIP;
DE   AltName: Full=Thyroid hormone receptor-binding protein;
GN   Name=NCOA6; Synonyms=AIB3, KIAA0181, RAP250, TRBP;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; TAS:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046965; F:retinoid X receptor binding; TAS:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0006310; P:DNA recombination; NAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0042921; P:glucocorticoid receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   NCOA2_HUMAN             Reviewed;        1464 AA.
AC   Q15596; Q14CD2;
DE   RecName: Full=Nuclear receptor coactivator 2;
DE            Short=NCoA-2;
DE   AltName: Full=Class E basic helix-loop-helix protein 75;
DE            Short=bHLHe75;
DE   AltName: Full=Transcriptional intermediary factor 2;
DE            Short=hTIF2;
GN   Name=NCOA2; Synonyms=BHLHE75, SRC2, TIF2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0030375; F:thyroid hormone receptor coactivator activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NCOA7_HUMAN             Reviewed;         942 AA.
AC   Q8NI08; B2RNS2; B7Z2C4; B9EH71; G8JL91; Q3LID6; Q4G0V1; Q5TF95;
AC   Q6IPQ4; Q6NE83; Q86T89; Q8N1W4;
DE   RecName: Full=Nuclear receptor coactivator 7;
DE   AltName: Full=140 kDa estrogen receptor-associated protein;
DE   AltName: Full=Estrogen nuclear receptor coactivator 1;
GN   Name=NCOA7; Synonyms=ERAP140, ESNA1; ORFNames=Nbla00052, Nbla10993;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NCLN_HUMAN              Reviewed;         563 AA.
AC   Q969V3; D6W613; O75252; Q6FI60; Q6ZMB7; Q8TAT7; Q96H48; Q96IS7;
AC   Q9BQH9; Q9BTX4; Q9NPP2;
DE   RecName: Full=Nicalin;
DE   AltName: Full=Nicastrin-like protein;
DE   Flags: Precursor;
GN   Name=NCLN;
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   NCOAT_HUMAN             Reviewed;         916 AA.
AC   O60502; B7WPB9; D3DR79; E9PGF9; O75166; Q86WV0; Q8IV98; Q9BVA5;
AC   Q9HAR0;
DE   RecName: Full=Bifunctional protein NCOAT;
DE   AltName: Full=Meningioma-expressed antigen 5;
DE   AltName: Full=Nuclear cytoplasmic O-GlcNAcase and acetyltransferase;
DE   Includes:
DE     RecName: Full=Protein O-GlcNAcase;
DE              EC=3.2.1.169;
DE     AltName: Full=Glycoside hydrolase O-GlcNAcase;
DE     AltName: Full=Hexosaminidase C;
DE     AltName: Full=N-acetyl-beta-D-glucosaminidase;
DE     AltName: Full=N-acetyl-beta-glucosaminidase;
DE     AltName: Full=O-GlcNAcase;
DE              Short=OGA;
DE   Includes:
DE     RecName: Full=Histone acetyltransferase;
DE              Short=HAT;
DE              EC=2.3.1.48;
GN   Name=MGEA5; Synonyms=HEXC, KIAA0679, MEA5;
DR   GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0046060; P:dATP metabolic process; IEA:Ensembl.
DR   GO; GO:0006516; P:glycoprotein catabolic process; TAS:ProtInc.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:Ensembl.
DR   GO; GO:0070265; P:necrotic cell death; IEA:Ensembl.
DR   GO; GO:0010616; P:negative regulation of cardiac muscle adaptation; IEA:Ensembl.
DR   GO; GO:0060051; P:negative regulation of protein glycosylation; IEA:Ensembl.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:0031343; P:positive regulation of cell killing; IEA:Ensembl.
DR   GO; GO:0051054; P:positive regulation of DNA metabolic process; IEA:Ensembl.
DR   GO; GO:0046326; P:positive regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0043243; P:positive regulation of protein complex disassembly; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0006612; P:protein targeting to membrane; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
//
ID   NCOR1_HUMAN             Reviewed;        2440 AA.
AC   O75376; B3DLF8; E9PGV6; Q86YY0; Q9UPV5; Q9UQ18;
DE   RecName: Full=Nuclear receptor corepressor 1;
DE            Short=N-CoR;
DE            Short=N-CoR1;
GN   Name=NCOR1; Synonyms=KIAA1047;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0035033; F:histone deacetylase regulator activity; IEA:Ensembl.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0002361; P:CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060318; P:definitive erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:2000191; P:regulation of fatty acid transport; IC:BHF-UCL.
DR   GO; GO:0072362; P:regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0072368; P:regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   NCOR2_HUMAN             Reviewed;        2525 AA.
AC   Q9Y618; O00613; O15416; O15421; Q13354; Q56D06; Q59GM0; Q9Y5U0;
DE   RecName: Full=Nuclear receptor corepressor 2;
DE            Short=N-CoR2;
DE   AltName: Full=CTG repeat protein 26;
DE   AltName: Full=SMAP270;
DE   AltName: Full=Silencing mediator of retinoic acid and thyroid hormone receptor;
DE            Short=SMRT;
DE   AltName: Full=T3 receptor-associating factor;
DE            Short=TRAC;
DE   AltName: Full=Thyroid-, retinoic-acid-receptor-associated corepressor;
GN   Name=NCOR2; Synonyms=CTG26;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005112; F:Notch binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0072365; P:regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   NCPR_HUMAN              Reviewed;         677 AA.
AC   P16435; Q16455; Q197M5; Q8N181; Q9H3M8; Q9UDT3;
DE   RecName: Full=NADPH--cytochrome P450 reductase;
DE            Short=CPR;
DE            Short=P450R;
DE            EC=1.6.2.4;
GN   Name=POR; Synonyms=CYPOR;
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; IEA:Ensembl.
DR   GO; GO:0009055; F:electron carrier activity; IEA:Ensembl.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:Ensembl.
DR   GO; GO:0010181; F:FMN binding; IEA:Ensembl.
DR   GO; GO:0016787; F:hydrolase activity; IEA:Ensembl.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0047726; F:iron-cytochrome-c reductase activity; IEA:Ensembl.
DR   GO; GO:0050661; F:NADP binding; IEA:Ensembl.
DR   GO; GO:0003958; F:NADPH-hemoprotein reductase activity; TAS:UniProtKB.
DR   GO; GO:0008941; F:nitric oxide dioxygenase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:Ensembl.
DR   GO; GO:0090346; P:cellular organofluorine metabolic process; IDA:BHF-UCL.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0070988; P:demethylation; IEA:Ensembl.
DR   GO; GO:0019395; P:fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0009812; P:flavonoid metabolic process; IEA:Ensembl.
DR   GO; GO:0018393; P:internal peptidyl-lysine acetylation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0060192; P:negative regulation of lipase activity; IEA:Ensembl.
DR   GO; GO:0043602; P:nitrate catabolic process; IEA:Ensembl.
DR   GO; GO:0046210; P:nitric oxide catabolic process; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0045542; P:positive regulation of cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032770; P:positive regulation of monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0090031; P:positive regulation of steroid hormone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0003420; P:regulation of growth plate cartilage chondrocyte proliferation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
//
ID   NCS1_HUMAN              Reviewed;         190 AA.
AC   P62166; E9PAY3; P36610; Q9UK26;
DE   RecName: Full=Neuronal calcium sensor 1;
DE            Short=NCS-1;
DE   AltName: Full=Frequenin homolog;
DE   AltName: Full=Frequenin-like protein;
DE   AltName: Full=Frequenin-like ubiquitous protein;
GN   Name=NCS1; Synonyms=FLUP, FREQ;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; ISS:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:Ensembl.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
//
ID   NCTR1_HUMAN             Reviewed;         304 AA.
AC   O76036; B0V3L2; B0V3L3; B0V3L4; B0V3L5; B8JL03; O76016; O76017;
AC   O76018;
DE   RecName: Full=Natural cytotoxicity triggering receptor 1;
DE   AltName: Full=Lymphocyte antigen 94 homolog;
DE   AltName: Full=NK cell-activating receptor;
DE   AltName: Full=Natural killer cell p46-related protein;
DE            Short=NK-p46;
DE            Short=NKp46;
DE            Short=hNKp46;
DE   AltName: CD_antigen=CD335;
DE   Flags: Precursor;
GN   Name=NCR1; Synonyms=LY94;
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
DR   GO; GO:0042269; P:regulation of natural killer cell mediated cytotoxicity; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NCTR2_HUMAN             Reviewed;         276 AA.
AC   O95944; Q9H562; Q9H563; Q9H564; Q9UMT1; Q9UMT2;
DE   RecName: Full=Natural cytotoxicity triggering receptor 2;
DE   AltName: Full=Lymphocyte antigen 95 homolog;
DE   AltName: Full=NK cell-activating receptor;
DE   AltName: Full=Natural killer cell p44-related protein;
DE            Short=NK-p44;
DE            Short=NKp44;
DE   AltName: CD_antigen=CD336;
DE   Flags: Precursor;
GN   Name=NCR2; Synonyms=LY95;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NCTR3_HUMAN             Reviewed;         201 AA.
AC   O14931; B0S8F2; B0S8F4; B0S8F5; O14930; O14932; O95667; O95668;
AC   O95669; Q5ST89; Q5ST90; Q5ST91; Q5ST92; Q5STA3;
DE   RecName: Full=Natural cytotoxicity triggering receptor 3;
DE   AltName: Full=Activating natural killer receptor p30;
DE   AltName: Full=Natural killer cell p30-related protein;
DE            Short=NK-p30;
DE            Short=NKp30;
DE   AltName: CD_antigen=CD337;
DE   Flags: Precursor;
GN   Name=NCR3; Synonyms=1C7, LY117;
DR   GO; GO:0008037; P:cell recognition; TAS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IMP:BHF-UCL.
//
ID   NCUG1_HUMAN             Reviewed;         406 AA.
AC   Q8WWB7; A6NH16; B4DJN4; Q5SZX4; Q6UX96; Q8IV07; Q96F65;
DE   RecName: Full=Lysosomal protein NCU-G1;
DE   Flags: Precursor;
GN   Name=C1orf85; ORFNames=PSEC0030, UNQ2553/PRO6182;
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IMP:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
//
ID   NCYM_HUMAN              Reviewed;         109 AA.
AC   P40205; Q53TD4;
DE   RecName: Full=N-cym protein;
DE   AltName: Full=N-myc opposite strand;
GN   Name=MYCNOS; Synonyms=CYMN, NCYM;
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   NDC1_HUMAN              Reviewed;         674 AA.
AC   Q9BTX1; Q8NB76; Q9H9T6; Q9NSG3; Q9NSG4; Q9NVZ7;
DE   RecName: Full=Nucleoporin NDC1;
DE            Short=hNDC1;
DE   AltName: Full=Transmembrane protein 48;
GN   Name=NDC1; Synonyms=TMEM48;
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IMP:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0031081; P:nuclear pore distribution; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; NAS:UniProtKB.
//
ID   NDC80_HUMAN             Reviewed;         642 AA.
AC   O14777; Q6PJX2;
DE   RecName: Full=Kinetochore protein NDC80 homolog;
DE   AltName: Full=Highly expressed in cancer protein;
DE   AltName: Full=Kinetochore protein Hec1;
DE            Short=HsHec1;
DE   AltName: Full=Kinetochore-associated protein 2;
DE   AltName: Full=Retinoblastoma-associated protein HEC;
GN   Name=NDC80; Synonyms=HEC, HEC1, KNTC2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; TAS:ProtInc.
DR   GO; GO:0007052; P:mitotic spindle organization; IMP:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; NAS:UniProtKB.
//
ID   NDE1_HUMAN              Reviewed;         346 AA.
AC   Q9NXR1; Q49AQ2;
DE   RecName: Full=Nuclear distribution protein nudE homolog 1;
DE            Short=NudE;
GN   Name=NDE1; Synonyms=NUDE;
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; ISS:UniProtKB.
DR   GO; GO:0021987; P:cerebral cortex development; IMP:UniProtKB.
DR   GO; GO:0051303; P:establishment of chromosome localization; IMP:UniProtKB.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IEA:Ensembl.
//
ID   NDEL1_HUMAN             Reviewed;         345 AA.
AC   Q9GZM8; B3KP93; D3DTS0; J3QT32; Q86T80; Q8TAR7; Q9UH50;
DE   RecName: Full=Nuclear distribution protein nudE-like 1;
DE            Short=Protein Nudel;
DE   AltName: Full=Mitosin-associated protein 1;
GN   Name=NDEL1; Synonyms=EOPA, MITAP1, NUDEL;
DR   GO; GO:0070012; F:oligopeptidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032864; P:activation of Cdc42 GTPase activity; IEA:Ensembl.
DR   GO; GO:0021955; P:central nervous system neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0060052; P:neurofilament cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0051081; P:nuclear envelope disassembly; IEA:Ensembl.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0048680; P:positive regulation of axon regeneration; IEA:Ensembl.
DR   GO; GO:0008090; P:retrograde axon cargo transport; IEA:Ensembl.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IEA:Ensembl.
//
ID   NDF1_HUMAN              Reviewed;         356 AA.
AC   Q13562; B2R9I8; F1T0E1; O00343; Q13340; Q5U095; Q96TH0; Q99455;
AC   Q9UEC8;
DE   RecName: Full=Neurogenic differentiation factor 1;
DE            Short=NeuroD;
DE            Short=NeuroD1;
DE   AltName: Full=Class A basic helix-loop-helix protein 3;
DE            Short=bHLHa3;
GN   Name=NEUROD1; Synonyms=BHLHA3, NEUROD;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0035881; P:amacrine cell differentiation; ISS:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; ISS:UniProtKB.
DR   GO; GO:0021542; P:dentate gyrus development; ISS:UniProtKB.
DR   GO; GO:0048562; P:embryonic organ morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.
DR   GO; GO:0035883; P:enteroendocrine cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:BHF-UCL.
DR   GO; GO:0048839; P:inner ear development; ISS:UniProtKB.
DR   GO; GO:0030073; P:insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:2000675; P:negative regulation of type B pancreatic cell apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0022008; P:neurogenesis; TAS:BHF-UCL.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IDA:BHF-UCL.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0003326; P:pancreatic A cell fate commitment; IEA:Ensembl.
DR   GO; GO:0003329; P:pancreatic PP cell fate commitment; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0071156; P:regulation of cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; IC:BHF-UCL.
DR   GO; GO:0060730; P:regulation of intestinal epithelial structure maintenance; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IMP:BHF-UCL.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
//
ID   NDF2_HUMAN              Reviewed;         382 AA.
AC   Q15784; Q8TBI7; Q9UQC6;
DE   RecName: Full=Neurogenic differentiation factor 2;
DE            Short=NeuroD2;
DE   AltName: Full=Class A basic helix-loop-helix protein 1;
DE            Short=bHLHa1;
DE   AltName: Full=NeuroD-related factor;
DE            Short=NDRF;
GN   Name=NEUROD2; Synonyms=BHLHA1, NDRF;
DR   GO; GO:0070888; F:E-box binding; ISS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; ISS:UniProtKB.
DR   GO; GO:0021695; P:cerebellar cortex development; ISS:UniProtKB.
DR   GO; GO:2000297; P:negative regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NDF4_HUMAN              Reviewed;         331 AA.
AC   Q9HD90; B2RAC9;
DE   RecName: Full=Neurogenic differentiation factor 4;
DE            Short=NeuroD4;
DE   AltName: Full=Class A basic helix-loop-helix protein 4;
DE            Short=bHLHa4;
DE   AltName: Full=Protein atonal homolog 3;
DE            Short=ATH-3;
DE            Short=Atoh3;
GN   Name=NEUROD4; Synonyms=ATH3, ATOH3, BHLHA4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035881; P:amacrine cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NDF6_HUMAN              Reviewed;         337 AA.
AC   Q96NK8; Q548T9; Q9H3H6;
DE   RecName: Full=Neurogenic differentiation factor 6;
DE            Short=NeuroD6;
DE   AltName: Full=Class A basic helix-loop-helix protein 2;
DE            Short=bHLHa2;
DE   AltName: Full=Protein atonal homolog 2;
GN   Name=NEUROD6; Synonyms=ATOH2, BHLHA2; ORFNames=My051;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NDK6_HUMAN              Reviewed;         186 AA.
AC   O75414; B4DGW7; B4DM99; Q53HM5; Q96E73; Q9BQ63;
DE   RecName: Full=Nucleoside diphosphate kinase 6;
DE            Short=NDK 6;
DE            Short=NDP kinase 6;
DE            EC=2.7.4.6;
DE   AltName: Full=Inhibitor of p53-induced apoptosis-alpha;
DE            Short=IPIA-alpha;
DE   AltName: Full=nm23-H6;
GN   Name=NME6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045839; P:negative regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDK7_HUMAN              Reviewed;         376 AA.
AC   Q9Y5B8; A8K3T6; A8MY09; B3KSW9; Q5TGZ4;
DE   RecName: Full=Nucleoside diphosphate kinase 7;
DE            Short=NDK 7;
DE            Short=NDP kinase 7;
DE            EC=2.7.4.6;
DE   AltName: Full=nm23-H7;
GN   Name=NME7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0042073; P:intraciliary transport; IEA:Ensembl.
DR   GO; GO:0060972; P:left/right pattern formation; IEA:Ensembl.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDK3_HUMAN              Reviewed;         169 AA.
AC   Q13232; Q9BWH4;
DE   RecName: Full=Nucleoside diphosphate kinase 3;
DE            Short=NDK 3;
DE            Short=NDP kinase 3;
DE            EC=2.7.4.6;
DE   AltName: Full=DR-nm23;
DE   AltName: Full=Nucleoside diphosphate kinase C;
DE            Short=NDPKC;
DE   AltName: Full=nm23-H3;
GN   Name=NME3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDK8_HUMAN              Reviewed;         137 AA.
AC   O60361;
DE   RecName: Full=Putative nucleoside diphosphate kinase;
DE            Short=NDK;
DE            Short=NDP kinase;
DE            EC=2.7.4.6;
GN   Name=NME2P1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDK5_HUMAN              Reviewed;         212 AA.
AC   P56597; B2R5G7;
DE   RecName: Full=Nucleoside diphosphate kinase homolog 5;
DE            Short=NDK-H 5;
DE            Short=NDP kinase homolog 5;
DE   AltName: Full=Inhibitor of p53-induced apoptosis-beta;
DE            Short=IPIA-beta;
DE   AltName: Full=Testis-specific nm23 homolog;
DE   AltName: Full=nm23-H5;
GN   Name=NME5;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; TAS:ProtInc.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0009116; P:nucleoside metabolic process; TAS:ProtInc.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
//
ID   NDKA_HUMAN              Reviewed;         152 AA.
AC   P15531; Q6FGK3; Q86XQ2; Q9UDJ6;
DE   RecName: Full=Nucleoside diphosphate kinase A;
DE            Short=NDK A;
DE            Short=NDP kinase A;
DE            EC=2.7.4.6;
DE   AltName: Full=Granzyme A-activated DNase;
DE            Short=GAAD;
DE   AltName: Full=Metastasis inhibition factor nm23;
DE   AltName: Full=NM23-H1;
DE   AltName: Full=Tumor metastatic process-associated protein;
GN   Name=NME1; Synonyms=NDPKA, NM23;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004536; F:deoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IPI:UniProtKB.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006308; P:DNA catabolic process; IDA:GOC.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0002762; P:negative regulation of myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:HGNC.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDKM_HUMAN              Reviewed;         187 AA.
AC   O00746; A2IDD0; Q5U0M9;
DE   RecName: Full=Nucleoside diphosphate kinase, mitochondrial;
DE            Short=NDK;
DE            Short=NDP kinase, mitochondrial;
DE            EC=2.7.4.6;
DE   AltName: Full=Nucleoside diphosphate kinase D;
DE            Short=NDPKD;
DE   AltName: Full=nm23-H4;
DE   Flags: Precursor;
GN   Name=NME4; Synonyms=NM23D;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009116; P:nucleoside metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDKB_HUMAN              Reviewed;         152 AA.
AC   P22392; A8MWA3; Q1WM23; Q6LCT6;
DE   RecName: Full=Nucleoside diphosphate kinase B;
DE            Short=NDK B;
DE            Short=NDP kinase B;
DE            EC=2.7.4.6;
DE   AltName: Full=C-myc purine-binding transcription factor PUF;
DE   AltName: Full=Histidine protein kinase NDKB;
DE            EC=2.7.13.3;
DE   AltName: Full=nm23-H2;
GN   Name=NME2; Synonyms=NM23B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:HGNC.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:HGNC.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009142; P:nucleoside triphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:HGNC.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:HGNC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045682; P:regulation of epidermis development; IMP:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   NDNF_HUMAN              Reviewed;         568 AA.
AC   Q8TB73; A8K0Q0; Q6UWE5; Q9H5P7;
DE   RecName: Full=Protein NDNF;
DE   AltName: Full=Neuron-derived neurotrophic factor;
DE   Flags: Precursor;
GN   Name=NDNF; Synonyms=C4orf31; ORFNames=UNQ2748/PRO6487;
DR   GO; GO:0005539; F:glycosaminoglycan binding; ISS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; ISS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IDA:UniProtKB.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; ISS:UniProtKB.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
//
ID   NDOR1_HUMAN             Reviewed;         597 AA.
AC   Q9UHB4; D3YTG6; D3YTH9; Q5VSG4; Q86US9; Q96BC6;
DE   RecName: Full=NADPH-dependent diflavin oxidoreductase 1;
DE            EC=1.6.-.-;
DE   AltName: Full=NADPH-dependent FMN and FAD-containing oxidoreductase;
DE   AltName: Full=Novel reductase 1;
GN   Name=NDOR1; Synonyms=NR1;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0010181; F:FMN binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IDA:UniProtKB.
DR   GO; GO:0003958; F:NADPH-hemoprotein reductase activity; IBA:RefGenome.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0036245; P:cellular response to menadione; IDA:UniProtKB.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-HAMAP.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDP_HUMAN               Reviewed;         133 AA.
AC   Q00604; B2R8K6; Q5JYH5;
DE   RecName: Full=Norrin;
DE   AltName: Full=Norrie disease protein;
DE   AltName: Full=X-linked exudative vitreoretinopathy 2 protein;
DE   Flags: Precursor;
GN   Name=NDP; Synonyms=EVR2;
DR   GO; GO:0005109; F:frizzled binding; IPI:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0035426; P:extracellular matrix-cell signaling; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; NAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007033; P:vacuole organization; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
//
ID   NDRG1_HUMAN             Reviewed;         394 AA.
AC   Q92597; B3KR80; B7Z446; O15207; Q6IBG2; Q9NYR6; Q9UK29;
DE   RecName: Full=Protein NDRG1;
DE   AltName: Full=Differentiation-related gene 1 protein;
DE            Short=DRG-1;
DE   AltName: Full=N-myc downstream-regulated gene 1 protein;
DE   AltName: Full=Nickel-specific induction protein Cap43;
DE   AltName: Full=Reducing agents and tunicamycin-responsive protein;
DE            Short=RTP;
DE   AltName: Full=Rit42;
GN   Name=NDRG1; Synonyms=CAP43, DRG1, RTP;
DR   GO; GO:0045296; F:cadherin binding; IDA:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IEP:UniProtKB.
DR   GO; GO:0045576; P:mast cell activation; IEA:Ensembl.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:0090232; P:positive regulation of spindle checkpoint; IDA:UniProtKB.
DR   GO; GO:0010038; P:response to metal ion; TAS:ProtInc.
//
ID   NDRG2_HUMAN             Reviewed;         371 AA.
AC   Q9UN36; B3KUE3; B4DE86; B7WP11; B7WPD5; D3DS07; D3DS10; Q567T1;
AC   Q68DW2; Q86U08; Q86U46; Q96FD3; Q96FT0; Q96JU0; Q96PN0; Q9BQH5;
AC   Q9ULH2;
DE   RecName: Full=Protein NDRG2;
DE   AltName: Full=N-myc downstream-regulated gene 2 protein;
DE   AltName: Full=Protein Syld709613;
GN   Name=NDRG2; Synonyms=KIAA1248, SYLD;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001818; P:negative regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0090361; P:regulation of platelet-derived growth factor production; IEA:Ensembl.
DR   GO; GO:0010574; P:regulation of vascular endothelial growth factor production; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NDRG3_HUMAN             Reviewed;         375 AA.
AC   Q9UGV2; A2A2S8; E1P5U7; E1P5U8; Q5TH32; Q96PL8; Q96SM2; Q9BXY7;
AC   Q9H3N7; Q9H411; Q9H8J6;
DE   RecName: Full=Protein NDRG3;
DE   AltName: Full=N-myc downstream-regulated gene 3 protein;
GN   Name=NDRG3;
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   NDRG4_HUMAN             Reviewed;         352 AA.
AC   Q9ULP0; B3KNU2; B4DK66; B4DSW5; H7C600; Q6ZNE7; Q6ZTI7; Q96PL9;
AC   Q9GZM1; Q9GZN3; Q9GZX0;
DE   RecName: Full=Protein NDRG4;
DE   AltName: Full=Brain development-related molecule 1;
DE   AltName: Full=N-myc downstream-regulated gene 4 protein;
DE   AltName: Full=Vascular smooth muscle cell-associated protein 8;
DE            Short=SMAP-8;
GN   Name=NDRG4; Synonyms=BDM1, KIAA1180;
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   NDST1_HUMAN             Reviewed;         882 AA.
AC   P52848; Q96E57;
DE   RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1;
DE            EC=2.8.2.8;
DE   AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 1;
DE            Short=NDST-1;
DE   AltName: Full=N-heparan sulfate sulfotransferase 1;
DE            Short=N-HSST 1;
DE   AltName: Full=[Heparan sulfate]-glucosamine N-sulfotransferase 1;
DE            Short=HSNST 1;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-deacetylase 1;
DE              EC=3.-.-.-;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-sulfotransferase 1;
DE              EC=2.8.2.-;
GN   Name=NDST1; Synonyms=HSST, HSST1;
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019213; F:deacetylase activity; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0048702; P:embryonic neurocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; TAS:ProtInc.
DR   GO; GO:0030210; P:heparin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   NDST2_HUMAN             Reviewed;         883 AA.
AC   P52849; Q2TB32; Q59H89;
DE   RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2;
DE            EC=2.8.2.8;
DE   AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 2;
DE            Short=NDST-2;
DE   AltName: Full=N-heparan sulfate sulfotransferase 2;
DE            Short=N-HSST 2;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-deacetylase 2;
DE              EC=3.-.-.-;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-sulfotransferase 2;
DE              EC=2.8.2.-;
GN   Name=NDST2; Synonyms=HSST2;
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030210; P:heparin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDST3_HUMAN             Reviewed;         873 AA.
AC   O95803; B4DI67; Q4W5C1; Q4W5D0; Q6UWC5; Q9UP21;
DE   RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3;
DE            EC=2.8.2.8;
DE   AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 3;
DE            Short=NDST-3;
DE            Short=hNDST-3;
DE   AltName: Full=N-heparan sulfate sulfotransferase 3;
DE            Short=N-HSST 3;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-deacetylase 3;
DE              EC=3.-.-.-;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-sulfotransferase 3;
DE              EC=2.8.2.-;
GN   Name=NDST3; Synonyms=HSST3; ORFNames=UNQ2544/PRO4998;
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0019213; F:deacetylase activity; IEA:Ensembl.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030210; P:heparin biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   NDST4_HUMAN             Reviewed;         872 AA.
AC   Q9H3R1;
DE   RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4;
DE            EC=2.8.2.8;
DE   AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 4;
DE            Short=NDST-4;
DE   AltName: Full=N-heparan sulfate sulfotransferase 4;
DE            Short=N-HSST 4;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-deacetylase 4;
DE              EC=3.-.-.-;
DE   Includes:
DE     RecName: Full=Heparan sulfate N-sulfotransferase 4;
DE              EC=2.8.2.-;
GN   Name=NDST4; Synonyms=HSST4;
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019213; F:deacetylase activity; IEA:Ensembl.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030210; P:heparin biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   NDUA1_HUMAN             Reviewed;          70 AA.
AC   O15239;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1;
DE   AltName: Full=Complex I-MWFE;
DE            Short=CI-MWFE;
DE   AltName: Full=NADH-ubiquinone oxidoreductase MWFE subunit;
GN   Name=NDUFA1;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA2_HUMAN             Reviewed;          99 AA.
AC   O43678; D6RJD6; Q6IAY8;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2;
DE   AltName: Full=Complex I-B8;
DE            Short=CI-B8;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B8 subunit;
GN   Name=NDUFA2;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA3_HUMAN             Reviewed;          84 AA.
AC   O95167;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3;
DE   AltName: Full=Complex I-B9;
DE            Short=CI-B9;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B9 subunit;
GN   Name=NDUFA3;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA4_HUMAN             Reviewed;          81 AA.
AC   O00483; A4D109; Q6FHN5;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4;
DE   AltName: Full=Complex I-MLRQ;
DE            Short=CI-MLRQ;
DE   AltName: Full=NADH-ubiquinone oxidoreductase MLRQ subunit;
GN   Name=NDUFA4;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA5_HUMAN             Reviewed;         116 AA.
AC   Q16718; B2RD98; Q6IRX7;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5;
DE   AltName: Full=Complex I subunit B13;
DE   AltName: Full=Complex I-13kD-B;
DE            Short=CI-13kD-B;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 13 kDa-B subunit;
GN   Name=NDUFA5;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA6_HUMAN             Reviewed;         154 AA.
AC   P56556; B2RE54; O43675; Q6FGW0; Q6IBT8; Q6IC39;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6;
DE   AltName: Full=Complex I-B14;
DE            Short=CI-B14;
DE   AltName: Full=LYR motif-containing protein 6;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B14 subunit;
GN   Name=NDUFA6; Synonyms=LYRM6, NADHB14;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA7_HUMAN             Reviewed;         113 AA.
AC   O95182;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7;
DE   AltName: Full=Complex I-B14.5a;
DE            Short=CI-B14.5a;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.5a;
GN   Name=NDUFA7;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA8_HUMAN             Reviewed;         172 AA.
AC   P51970; B1AM93; Q9Y6N0;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8;
DE   AltName: Full=Complex I-19kD;
DE            Short=CI-19kD;
DE   AltName: Full=Complex I-PGIV;
DE            Short=CI-PGIV;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 19 kDa subunit;
GN   Name=NDUFA8;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUA9_HUMAN             Reviewed;         377 AA.
AC   Q16795; Q14076; Q2NKX0;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial;
DE   AltName: Full=Complex I-39kD;
DE            Short=CI-39kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 39 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFA9; Synonyms=NDUFS2L;
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0003954; F:NADH dehydrogenase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
//
ID   NDUAA_HUMAN             Reviewed;         355 AA.
AC   O95299;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial;
DE   AltName: Full=Complex I-42kD;
DE            Short=CI-42kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 42 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFA10;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUAB_HUMAN             Reviewed;         141 AA.
AC   Q86Y39; C9JT23; Q6ZS66;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11;
DE   AltName: Full=Complex I-B14.7;
DE            Short=CI-B14.7;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.7;
GN   Name=NDUFA11;
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUAC_HUMAN             Reviewed;         145 AA.
AC   Q9UI09; F8VQS7; Q53XX0; Q9BRV6;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12;
DE   AltName: Full=13 kDa differentiation-associated protein;
DE   AltName: Full=Complex I-B17.2;
DE            Short=CI-B17.2;
DE            Short=CIB17.2;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B17.2;
GN   Name=NDUFA12; Synonyms=DAP13;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0007585; P:respiratory gaseous exchange; NAS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUAD_HUMAN             Reviewed;         144 AA.
AC   Q9P0J0; Q6PKI0; Q9H2L3; Q9Y327;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13;
DE   AltName: Full=Cell death regulatory protein GRIM-19;
DE   AltName: Full=Complex I-B16.6;
DE            Short=CI-B16.6;
DE   AltName: Full=Gene associated with retinoic and interferon-induced mortality 19 protein;
DE            Short=GRIM-19;
DE            Short=Gene associated with retinoic and IFN-induced mortality 19 protein;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B16.6 subunit;
GN   Name=NDUFA13; Synonyms=GRIM19; ORFNames=CDA016, CGI-39;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IDA:UniProtKB.
DR   GO; GO:0003954; F:NADH dehydrogenase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045039; P:protein import into mitochondrial inner membrane; IDA:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB1_HUMAN             Reviewed;          58 AA.
AC   O75438; A0AV68;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1;
DE   AltName: Full=Complex I-MNLL;
DE            Short=CI-MNLL;
DE   AltName: Full=NADH-ubiquinone oxidoreductase MNLL subunit;
GN   Name=NDUFB1;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB2_HUMAN             Reviewed;         105 AA.
AC   O95178; Q6FGI6;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial;
DE   AltName: Full=Complex I-AGGG;
DE            Short=CI-AGGG;
DE   AltName: Full=NADH-ubiquinone oxidoreductase AGGG subunit;
DE   Flags: Precursor;
GN   Name=NDUFB2;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB3_HUMAN             Reviewed;          98 AA.
AC   O43676; Q6IB80;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3;
DE   AltName: Full=Complex I-B12;
DE            Short=CI-B12;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B12 subunit;
GN   Name=NDUFB3;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB4_HUMAN             Reviewed;         129 AA.
AC   O95168; B2RUY3; B9EJC7;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4;
DE   AltName: Full=Complex I-B15;
DE            Short=CI-B15;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B15 subunit;
GN   Name=NDUFB4;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB5_HUMAN             Reviewed;         189 AA.
AC   O43674; Q561V6;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial;
DE   AltName: Full=Complex I-SGDH;
DE            Short=CI-SGDH;
DE   AltName: Full=NADH-ubiquinone oxidoreductase SGDH subunit;
DE   Flags: Precursor;
GN   Name=NDUFB5;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB6_HUMAN             Reviewed;         128 AA.
AC   O95139; A8K0Y7; Q5VYT2; Q6IB84;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6;
DE   AltName: Full=Complex I-B17;
DE            Short=CI-B17;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B17 subunit;
GN   Name=NDUFB6;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB7_HUMAN             Reviewed;         137 AA.
AC   P17568; Q6ICN9; Q9UI16;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7;
DE   AltName: Full=Cell adhesion protein SQM1;
DE   AltName: Full=Complex I-B18;
DE            Short=CI-B18;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B18 subunit;
GN   Name=NDUFB7;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB8_HUMAN             Reviewed;         186 AA.
AC   O95169; A8K0L4; Q5W143; Q5W144; Q5W145; Q9UG53; Q9UJR4; Q9UQF3;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial;
DE   AltName: Full=Complex I-ASHI;
DE            Short=CI-ASHI;
DE   AltName: Full=NADH-ubiquinone oxidoreductase ASHI subunit;
DE   Flags: Precursor;
GN   Name=NDUFB8;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUB9_HUMAN             Reviewed;         179 AA.
AC   Q9Y6M9; B2R8M6; Q9UQE8;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9;
DE   AltName: Full=Complex I-B22;
DE            Short=CI-B22;
DE   AltName: Full=LYR motif-containing protein 3;
DE   AltName: Full=NADH-ubiquinone oxidoreductase B22 subunit;
GN   Name=NDUFB9; Synonyms=LYRM3, UQOR22;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUBA_HUMAN             Reviewed;         172 AA.
AC   O96000;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10;
DE   AltName: Full=Complex I-PDSW;
DE            Short=CI-PDSW;
DE   AltName: Full=NADH-ubiquinone oxidoreductase PDSW subunit;
GN   Name=NDUFB10;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUBB_HUMAN             Reviewed;         153 AA.
AC   Q9NX14; Q5JRR3; Q5JRR4; Q6IAB6; Q8WZ96; Q9BXX9;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial;
DE   AltName: Full=Complex I-ESSS;
DE            Short=CI-ESSS;
DE   AltName: Full=NADH-ubiquinone oxidoreductase ESSS subunit;
DE   AltName: Full=Neuronal protein 17.3;
DE            Short=Np17.3;
DE            Short=p17.3;
DE   Flags: Precursor;
GN   Name=NDUFB11; ORFNames=UNQ111/PRO1064;
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUC1_HUMAN             Reviewed;          76 AA.
AC   O43677; A8K532; Q3MIJ9;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial;
DE   AltName: Full=Complex I-KFYI;
DE            Short=CI-KFYI;
DE   AltName: Full=NADH-ubiquinone oxidoreductase KFYI subunit;
DE   Flags: Precursor;
GN   Name=NDUFC1;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUC2_HUMAN             Reviewed;         119 AA.
AC   O95298; E9PNU8; E9PRB2; Q549M5; Q6FIH8; Q9UBJ9;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2;
DE   AltName: Full=Complex I-B14.5b;
DE            Short=CI-B14.5b;
DE   AltName: Full=Human lung cancer oncogene 1 protein;
DE            Short=HLC-1;
DE   AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.5b;
GN   Name=NDUFC2; ORFNames=HLC1;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUCR_HUMAN             Reviewed;         114 AA.
AC   E9PQ53;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2;
DE   AltName: Full=NDUFC2-KCTD14 readthrough transcript protein;
GN   Name=NDUFC2-KCTD14;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
//
ID   NDUF3_HUMAN             Reviewed;         184 AA.
AC   Q9BU61;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3;
GN   Name=NDUFAF3; Synonyms=C3orf60;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
//
ID   NDUF4_HUMAN             Reviewed;         175 AA.
AC   Q9P032; B2R4J5;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4;
DE   AltName: Full=Hormone-regulated proliferation-associated protein of 20 kDa;
GN   Name=NDUFAF4; Synonyms=C6orf66, HRPAP20; ORFNames=HSPC125, My013;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
//
ID   NDUF5_HUMAN             Reviewed;         345 AA.
AC   Q5TEU4; A8K166; Q6GPH3; Q9H6F4;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5;
DE   AltName: Full=Probable methyltransferase C20orf7, mitochondrial;
DE            EC=2.1.1.-;
DE   Flags: Precursor;
GN   Name=NDUFAF5; Synonyms=C20orf7;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
//
ID   NDUF7_HUMAN             Reviewed;         441 AA.
AC   Q7L592; Q7Z399; Q9P1G3;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] complex I, assembly factor 7;
DE   AltName: Full=Protein midA homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=NDUFAF7; Synonyms=C2orf56; ORFNames=PRO1853;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0008168; F:methyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0032259; P:methylation; NAS:GOC.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
//
ID   NDUF6_HUMAN             Reviewed;         333 AA.
AC   Q330K2; A8MT28; A8MWF0; B4DQ45; Q8N6U6;
DE   RecName: Full=NADH dehydrogenase (ubiquinone) complex I, assembly factor 6;
DE   AltName: Full=Putative phytoene synthase;
DE   Flags: Precursor;
GN   Name=NDUFAF6; Synonyms=C8orf38;
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
//
ID   NDUS1_HUMAN             Reviewed;         727 AA.
AC   P28331; B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; Q53TR8; Q8N1C4;
AC   Q8TCC9;
DE   RecName: Full=NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=Complex I-75kD;
DE            Short=CI-75kD;
DE   Flags: Precursor;
GN   Name=NDUFS1;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IDA:UniProtKB.
DR   GO; GO:0046034; P:ATP metabolic process; IMP:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0045333; P:cellular respiration; IMP:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUS2_HUMAN             Reviewed;         463 AA.
AC   O75306; D3DVG7; J3KPM7; Q5VTW0; Q969P3; Q9UEV3;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=Complex I-49kD;
DE            Short=CI-49kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 49 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFS2;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUS3_HUMAN             Reviewed;         264 AA.
AC   O75489; B2R9J1; Q9UNQ8;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=Complex I-30kD;
DE            Short=CI-30kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 30 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFS3;
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0003954; F:NADH dehydrogenase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   NDUS4_HUMAN             Reviewed;         175 AA.
AC   O43181; Q9BS69;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial;
DE   AltName: Full=Complex I-18 kDa;
DE            Short=CI-18 kDa;
DE   AltName: Full=Complex I-AQDQ;
DE            Short=CI-AQDQ;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 18 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFS4;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IMP:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0045333; P:cellular respiration; IMP:UniProtKB.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IMP:MGI.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0051591; P:response to cAMP; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUS5_HUMAN             Reviewed;         106 AA.
AC   O43920;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 5;
DE   AltName: Full=Complex I-15 kDa;
DE            Short=CI-15 kDa;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 15 kDa subunit;
GN   Name=NDUFS5;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUS6_HUMAN             Reviewed;         124 AA.
AC   O75380;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial;
DE   AltName: Full=Complex I-13kD-A;
DE            Short=CI-13kD-A;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 13 kDa-A subunit;
DE   Flags: Precursor;
GN   Name=NDUFS6;
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0072358; P:cardiovascular system development; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
DR   GO; GO:0061458; P:reproductive system development; IEA:Ensembl.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUS7_HUMAN             Reviewed;         213 AA.
AC   O75251; Q2T9H7; Q9BV17;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=Complex I-20kD;
DE            Short=CI-20kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 20 kDa subunit;
DE   AltName: Full=PSST subunit;
DE   Flags: Precursor;
GN   Name=NDUFS7;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0016655; F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUS8_HUMAN             Reviewed;         210 AA.
AC   O00217; B2RB86; Q0VDA8;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=Complex I-23kD;
DE            Short=CI-23kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 23 kDa subunit;
DE   AltName: Full=TYKY subunit;
DE   Flags: Precursor;
GN   Name=NDUFS8;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUV1_HUMAN             Reviewed;         464 AA.
AC   P49821; O60924; O60940; Q16104; Q6IBR3; Q96BF8; Q96HS7;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=Complex I-51kD;
DE            Short=CI-51kD;
DE   AltName: Full=NADH dehydrogenase flavoprotein 1;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 51 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFV1; Synonyms=UQOR1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUV2_HUMAN             Reviewed;         249 AA.
AC   P19404; Q9BV41;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial;
DE            EC=1.6.5.3;
DE            EC=1.6.99.3;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 24 kDa subunit;
DE   Flags: Precursor;
GN   Name=NDUFV2;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron carrier activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IMP:UniProtKB.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IMP:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NDUV3_HUMAN             Reviewed;         108 AA.
AC   P56181; A8K0M1; J3KNX7; Q6FGD3; Q8WU60; Q9HCR5;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial;
DE   AltName: Full=Complex I-9kD;
DE            Short=CI-9kD;
DE   AltName: Full=NADH-ubiquinone oxidoreductase 9 kDa subunit;
DE   AltName: Full=Renal carcinoma antigen NY-REN-4;
DE   Flags: Precursor;
GN   Name=NDUFV3;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NEAS1_HUMAN             Reviewed;         246 AA.
AC   Q8NBZ9;
DE   RecName: Full=Putative uncharacterized protein NEXN-AS1;
DE   AltName: Full=NEXN antisense RNA 1;
GN   Name=NEXN-AS1; Synonyms=C1orf118;
//
ID   NEB1_HUMAN              Reviewed;        1098 AA.
AC   Q9ULJ8; A1L494; B2RWQ1; E9PCA0; E9PCK6; E9PDX1; F8W7J9; O76059;
AC   Q9NXT2;
DE   RecName: Full=Neurabin-1;
DE   AltName: Full=Neurabin-I;
DE   AltName: Full=Neural tissue-specific F-actin-binding protein I;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 9A;
GN   Name=PPP1R9A; Synonyms=KIAA1222;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
//
ID   NEB2_HUMAN              Reviewed;         815 AA.
AC   Q96SB3; Q8TCR9;
DE   RecName: Full=Neurabin-2;
DE   AltName: Full=Neurabin-II;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 9B;
DE   AltName: Full=Spinophilin;
GN   Name=PPP1R9B; Synonyms=PPP1R6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; NAS:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0071315; P:cellular response to morphine; ISS:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0046847; P:filopodium assembly; IMP:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0001560; P:regulation of cell growth by extracellular stimulus; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007096; P:regulation of exit from mitosis; NAS:UniProtKB.
DR   GO; GO:2000474; P:regulation of opioid receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; NAS:UniProtKB.
//
ID   NEBL_HUMAN              Reviewed;        1014 AA.
AC   O76041; B0YJ45; Q2TBD0; Q70I54; Q9UIC4;
DE   RecName: Full=Nebulette;
DE   AltName: Full=Actin-binding Z-disk protein;
GN   Name=NEBL; Synonyms=LNEBL;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:UniProtKB.
DR   GO; GO:0031005; F:filamin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.
DR   GO; GO:0005523; F:tropomyosin binding; IPI:UniProtKB.
DR   GO; GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB.
//
ID   NEBU_HUMAN              Reviewed;        6669 AA.
AC   P20929; F8WCL5; F8WCP0; Q15346; Q53QQ2; Q53TG8;
DE   RecName: Full=Nebulin;
GN   Name=NEB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.
DR   GO; GO:0007525; P:somatic muscle development; NAS:UniProtKB.
//
ID   NEC1_HUMAN              Reviewed;         753 AA.
AC   P29120; B7Z8T7; E9PHA1; P78478; Q92532;
DE   RecName: Full=Neuroendocrine convertase 1;
DE            Short=NEC 1;
DE            EC=3.4.21.93;
DE   AltName: Full=Prohormone convertase 1;
DE   AltName: Full=Proprotein convertase 1;
DE            Short=PC1;
DE   Flags: Precursor;
GN   Name=PCSK1; Synonyms=NEC1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; ISS:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0043043; P:peptide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
//
ID   NEC2_HUMAN              Reviewed;         638 AA.
AC   P16519; B1ANH9; B4DFQ3; Q14927; Q5JYQ1; Q8IWA8; Q9NQG3; Q9NUG1;
AC   Q9UJC6;
DE   RecName: Full=Neuroendocrine convertase 2;
DE            Short=NEC 2;
DE            EC=3.4.21.94;
DE   AltName: Full=KEX2-like endoprotease 2;
DE   AltName: Full=Prohormone convertase 2;
DE   AltName: Full=Proprotein convertase 2;
DE            Short=PC2;
DE   Flags: Precursor;
GN   Name=PCSK2; Synonyms=NEC2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0034230; P:enkephalin processing; ISS:BHF-UCL.
DR   GO; GO:0030070; P:insulin processing; IDA:BHF-UCL.
DR   GO; GO:0034231; P:islet amyloid polypeptide processing; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0016540; P:protein autoprocessing; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:BHF-UCL.
//
ID   NECA2_HUMAN             Reviewed;         386 AA.
AC   Q7Z6G3; A2RRG3; O75547; Q6ZSK0;
DE   RecName: Full=N-terminal EF-hand calcium-binding protein 2;
DE            Short=EF-hand calcium-binding protein 2;
DE   AltName: Full=Neuronal calcium-binding protein 2;
DE   AltName: Full=Synaptotagmin-interacting protein 2;
DE            Short=Stip-2;
GN   Name=NECAB2; Synonyms=EFCBP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NECA1_HUMAN             Reviewed;         351 AA.
AC   Q8N987; Q6NUS7; Q96AZ7; Q9HBW8;
DE   RecName: Full=N-terminal EF-hand calcium-binding protein 1;
DE            Short=EF-hand calcium-binding protein 1;
DE   AltName: Full=Neuronal calcium-binding protein 1;
GN   Name=NECAB1; Synonyms=EFCBP1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   NECA3_HUMAN             Reviewed;         396 AA.
AC   Q96P71; A8K780; E1P5N2; Q5JWF5; Q5JWF6; Q5JWF7; Q86VV1; Q9H433;
AC   Q9H8G8; Q9HBW7; Q9HCQ9;
DE   RecName: Full=N-terminal EF-hand calcium-binding protein 3;
DE   AltName: Full=Amyloid beta A4 protein-binding family A member 2-binding protein;
DE   AltName: Full=Nek2-interacting protein 1;
DE   AltName: Full=Neuronal calcium-binding protein 3;
DE   AltName: Full=X11L-binding protein 51;
GN   Name=NECAB3; Synonyms=APBA2BP, NIP1, SYTIP2, XB51;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019538; P:protein metabolic process; IDA:UniProtKB.
DR   GO; GO:0009306; P:protein secretion; NAS:UniProtKB.
DR   GO; GO:0042984; P:regulation of amyloid precursor protein biosynthetic process; IDA:UniProtKB.
//
ID   NECD_HUMAN              Reviewed;         321 AA.
AC   Q99608; B2R6Z5;
DE   RecName: Full=Necdin;
GN   Name=NDN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0071514; P:genetic imprinting; IEA:Ensembl.
DR   GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR   GO; GO:0048871; P:multicellular organismal homeostasis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NECP1_HUMAN             Reviewed;         275 AA.
AC   Q8NC96; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NCB0; Q9BU52; Q9Y407;
DE   RecName: Full=Adaptin ear-binding coat-associated protein 1;
DE   AltName: Full=NECAP endocytosis-associated protein 1;
DE            Short=NECAP-1;
GN   Name=NECAP1;
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NECP2_HUMAN             Reviewed;         263 AA.
AC   Q9NVZ3; B4DY19; E9PGQ8; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1;
DE   RecName: Full=Adaptin ear-binding coat-associated protein 2;
DE   AltName: Full=NECAP endocytosis-associated protein 2;
DE            Short=NECAP-2;
GN   Name=NECAP2;
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NED4L_HUMAN             Reviewed;         975 AA.
AC   Q96PU5; O43165; Q3LSM7; Q7Z5F1; Q7Z5F2; Q7Z5N3; Q8N5A7; Q8WUU9;
AC   Q9BW58; Q9H2W4; Q9NT88;
DE   RecName: Full=E3 ubiquitin-protein ligase NEDD4-like;
DE            EC=6.3.2.-;
DE   AltName: Full=NEDD4.2;
DE   AltName: Full=Nedd4-2;
GN   Name=NEDD4L; Synonyms=KIAA0439, NEDL3;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0019870; F:potassium channel inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019871; F:sodium channel inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0006883; P:cellular sodium ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0007588; P:excretion; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:1901380; P:negative regulation of potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:1901017; P:negative regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:1902306; P:negative regulation of sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:2000650; P:negative regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0003085; P:negative regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2001259; P:positive regulation of cation channel activity; IEA:Ensembl.
DR   GO; GO:2001288; P:positive regulation of caveolin-mediated endocytosis; ISS:BHF-UCL.
DR   GO; GO:0045807; P:positive regulation of endocytosis; NAS:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0003254; P:regulation of membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:0060306; P:regulation of membrane repolarization; IDA:BHF-UCL.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0042176; P:regulation of protein catabolic process; NAS:UniProtKB.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IEA:Ensembl.
DR   GO; GO:0010038; P:response to metal ion; IDA:UniProtKB.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:Ensembl.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; ISS:BHF-UCL.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0030104; P:water homeostasis; NAS:UniProtKB.
//
ID   NEDD1_HUMAN             Reviewed;         660 AA.
AC   Q8NHV4; B0AZN0; B4E145; G3V3F1; Q8NA30;
DE   RecName: Full=Protein NEDD1;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 1;
DE            Short=NEDD-1;
GN   Name=NEDD1;
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   NEDD4_HUMAN             Reviewed;        1319 AA.
AC   P46934; A1KY35; A6ND72; A7MD29; B4E2R7; B7ZM59; B7ZM60; B9EGN5;
AC   D6RF89;
DE   RecName: Full=E3 ubiquitin-protein ligase NEDD4;
DE            EC=6.3.2.-;
DE   AltName: Full=Cell proliferation-inducing gene 53 protein;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 4;
DE            Short=NEDD-4;
GN   Name=NEDD4; Synonyms=KIAA0093, NEDD4-1; ORFNames=PIG53;
DR   GO; GO:0031698; F:beta-2 adrenergic receptor binding; IDA:UniProtKB.
DR   GO; GO:0050815; F:phosphoserine binding; ISS:BHF-UCL.
DR   GO; GO:0050816; F:phosphothreonine binding; ISS:BHF-UCL.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0070063; F:RNA polymerase binding; IPI:BHF-UCL.
DR   GO; GO:0019871; F:sodium channel inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
DR   GO; GO:0002250; P:adaptive immune response; IEA:Ensembl.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IMP:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0044111; P:development involved in symbiotic interaction; IMP:UniProtKB.
DR   GO; GO:0003197; P:endocardial cushion development; IEA:Ensembl.
DR   GO; GO:0042921; P:glucocorticoid receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007041; P:lysosomal transport; IDA:UniProtKB.
DR   GO; GO:0010766; P:negative regulation of sodium ion transport; IDA:UniProtKB.
DR   GO; GO:0010768; P:negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:BHF-UCL.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEP:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0046824; P:positive regulation of nucleocytoplasmic transport; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.
DR   GO; GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IEA:Ensembl.
DR   GO; GO:0006622; P:protein targeting to lysosome; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0032801; P:receptor catabolic process; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0050807; P:regulation of synapse organization; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; TAS:BHF-UCL.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0019089; P:transmission of virus; IMP:BHF-UCL.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:BHF-UCL.
//
ID   NEDD8_HUMAN             Reviewed;          81 AA.
AC   Q15843; Q3SXN8; Q6LES6;
DE   RecName: Full=NEDD8;
DE   AltName: Full=Neddylin;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 8;
DE            Short=NEDD-8;
DE   AltName: Full=Ubiquitin-like protein Nedd8;
DE   Flags: Precursor;
GN   Name=NEDD8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0045116; P:protein neddylation; IDA:MGI.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   NEGR1_HUMAN             Reviewed;         354 AA.
AC   Q7Z3B1; Q5VT21; Q6UY06; Q8NAQ3;
DE   RecName: Full=Neuronal growth regulator 1;
DE   AltName: Full=IgLON family member 4;
DE   Flags: Precursor;
GN   Name=NEGR1; Synonyms=IGLON4; ORFNames=UNQ2433/PRO4993;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
//
ID   NEIL1_HUMAN             Reviewed;         390 AA.
AC   Q96FI4; D3DW75; Q6ZRA7; Q86XW7; Q9H6C3;
DE   RecName: Full=Endonuclease 8-like 1;
DE            EC=3.2.2.-;
DE            EC=4.2.99.18;
DE   AltName: Full=DNA glycosylase/AP lyase Neil1;
DE   AltName: Full=DNA-(apurinic or apyrimidinic site) lyase Neil1;
DE   AltName: Full=Endonuclease VIII-like 1;
DE   AltName: Full=FPG1;
DE   AltName: Full=Nei homolog 1;
DE            Short=NEH1;
DE   AltName: Full=Nei-like protein 1;
GN   Name=NEIL1;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0019104; F:DNA N-glycosylase activity; IEA:Ensembl.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IDA:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0032074; P:negative regulation of nuclease activity; IDA:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
//
ID   NEIL2_HUMAN             Reviewed;         332 AA.
AC   Q969S2; B4DFR7; Q7Z3Q7; Q8N842; Q8NG52;
DE   RecName: Full=Endonuclease 8-like 2;
DE            EC=3.2.2.-;
DE            EC=4.2.99.18;
DE   AltName: Full=DNA glycosylase/AP lyase Neil2;
DE   AltName: Full=DNA-(apurinic or apyrimidinic site) lyase Neil2;
DE   AltName: Full=Endonuclease VIII-like 2;
DE   AltName: Full=Nei homolog 2;
DE            Short=NEH2;
DE   AltName: Full=Nei-like protein 2;
GN   Name=NEIL2;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016799; F:hydrolase activity, hydrolyzing N-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
//
ID   NEIL3_HUMAN             Reviewed;         605 AA.
AC   Q8TAT5; Q2PPJ3; Q8NG51; Q9NV95;
DE   RecName: Full=Endonuclease 8-like 3;
DE            EC=3.2.2.-;
DE            EC=4.2.99.18;
DE   AltName: Full=DNA glycosylase FPG2;
DE   AltName: Full=DNA glycosylase/AP lyase Neil3;
DE   AltName: Full=Endonuclease VIII-like 3;
DE   AltName: Full=Nei-like protein 3;
GN   Name=NEIL3;
DR   GO; GO:0000405; F:bubble DNA binding; ISS:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0019104; F:DNA N-glycosylase activity; ISS:UniProtKB.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; ISS:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
//
ID   NEK10_HUMAN             Reviewed;        1172 AA.
AC   Q6ZWH5; A8MWG1; B9ZVR0; Q45VJ4; Q6ZR11; Q7Z671; Q86XB1; Q96MB3;
DE   RecName: Full=Serine/threonine-protein kinase Nek10;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 10;
DE            Short=NimA-related protein kinase 10;
GN   Name=NEK10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
//
ID   NEK11_HUMAN             Reviewed;         645 AA.
AC   Q8NG66; A6NHD7; Q5JPC0; Q8NG65; Q8TBY1; Q9H5F4;
DE   RecName: Full=Serine/threonine-protein kinase Nek11;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 11;
DE            Short=NimA-related protein kinase 11;
GN   Name=NEK11;
DR   GuidetoPHARMACOLOGY; 2116; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   NEK1_HUMAN              Reviewed;        1258 AA.
AC   Q96PY6; G5E9Z3; Q05DG5; Q14CB7; Q5H9T1; Q6PIB8; Q96SS2; Q9H6P7;
AC   Q9Y594;
DE   RecName: Full=Serine/threonine-protein kinase Nek1;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 1;
DE            Short=NimA-related protein kinase 1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-55;
GN   Name=NEK1; Synonyms=KIAA1901;
DR   GuidetoPHARMACOLOGY; 2114; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:MGI.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
//
ID   NEK2_HUMAN              Reviewed;         445 AA.
AC   P51955; Q53FD6; Q5I1Z9; Q5VXZ1; Q6NZX8; Q7Z634; Q86XH2; Q96QN9;
DE   RecName: Full=Serine/threonine-protein kinase Nek2;
DE            EC=2.7.11.1;
DE   AltName: Full=HSPK 21;
DE   AltName: Full=Never in mitosis A-related kinase 2;
DE            Short=NimA-related protein kinase 2;
DE   AltName: Full=NimA-like protein kinase 1;
GN   Name=NEK2; Synonyms=NEK2A, NLK1;
DR   GuidetoPHARMACOLOGY; 2117; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0051299; P:centrosome separation; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
DR   GO; GO:0046602; P:regulation of mitotic centrosome separation; TAS:UniProtKB.
DR   GO; GO:0051225; P:spindle assembly; TAS:UniProtKB.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IEA:Ensembl.
//
ID   NEK3_HUMAN              Reviewed;         506 AA.
AC   P51956; A8K2J4; Q5TAP2; Q8J023; Q8WUN5;
DE   RecName: Full=Serine/threonine-protein kinase Nek3;
DE            EC=2.7.11.1;
DE   AltName: Full=HSPK 36;
DE   AltName: Full=Never in mitosis A-related kinase 3;
DE            Short=NimA-related protein kinase 3;
GN   Name=NEK3;
DR   GuidetoPHARMACOLOGY; 2118; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
//
ID   NEK4_HUMAN              Reviewed;         841 AA.
AC   P51957; A5YM70; B2R633; B7Z200; Q6P576;
DE   RecName: Full=Serine/threonine-protein kinase Nek4;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 4;
DE            Short=NimA-related protein kinase 4;
DE   AltName: Full=Serine/threonine-protein kinase 2;
DE   AltName: Full=Serine/threonine-protein kinase NRK2;
GN   Name=NEK4; Synonyms=STK2;
DR   GuidetoPHARMACOLOGY; 2119; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   NEK5_HUMAN              Reviewed;         708 AA.
AC   Q6P3R8; Q5TAP5;
DE   RecName: Full=Serine/threonine-protein kinase Nek5;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 5;
DE            Short=NimA-related protein kinase 5;
GN   Name=NEK5;
DR   GuidetoPHARMACOLOGY; 2120; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   NEK6_HUMAN              Reviewed;         313 AA.
AC   Q9HC98; B7Z2D9; Q5TBG3; Q5TBG9; Q6FG86; Q6IAR3; Q96E83; Q9ULX2;
DE   RecName: Full=Serine/threonine-protein kinase Nek6;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 6;
DE            Short=NimA-related protein kinase 6;
DE   AltName: Full=Protein kinase SID6-1512;
GN   Name=NEK6;
DR   GuidetoPHARMACOLOGY; 2121; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IDA:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000772; P:regulation of cellular senescence; TAS:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0051225; P:spindle assembly; TAS:UniProtKB.
//
ID   NEK7_HUMAN              Reviewed;         302 AA.
AC   Q8TDX7; A6NGT8;
DE   RecName: Full=Serine/threonine-protein kinase Nek7;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 7;
DE            Short=NimA-related protein kinase 7;
GN   Name=NEK7;
DR   GuidetoPHARMACOLOGY; 2122; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0051225; P:spindle assembly; TAS:UniProtKB.
//
ID   NEK8_HUMAN              Reviewed;         692 AA.
AC   Q86SG6; A6NIC5; Q14CL7; Q2M1S6; Q8NDH1;
DE   RecName: Full=Serine/threonine-protein kinase Nek8;
DE            EC=2.7.11.1;
DE   AltName: Full=Never in mitosis A-related kinase 8;
DE            Short=NimA-related protein kinase 8;
DE   AltName: Full=Nima-related protein kinase 12a;
GN   Name=NEK8; Synonyms=JCK, NEK12A;
DR   GuidetoPHARMACOLOGY; 2123; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:organ morphogenesis; IMP:UniProtKB.
DR   GO; GO:0035330; P:regulation of hippo signaling; IDA:UniProtKB.
//
ID   NEK9_HUMAN              Reviewed;         979 AA.
AC   Q8TD19; Q52LK6; Q8NCN0; Q8TCY4; Q9UPI4; Q9Y6S4; Q9Y6S5; Q9Y6S6;
DE   RecName: Full=Serine/threonine-protein kinase Nek9;
DE            EC=2.7.11.1;
DE   AltName: Full=Nercc1 kinase;
DE   AltName: Full=Never in mitosis A-related kinase 9;
DE            Short=NimA-related protein kinase 9;
DE   AltName: Full=NimA-related kinase 8;
DE            Short=Nek8;
GN   Name=NEK9; Synonyms=KIAA1995, NEK8, NERCC;
DR   GuidetoPHARMACOLOGY; 2124; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; EXP:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
//
ID   NELFA_HUMAN             Reviewed;         528 AA.
AC   Q9H3P2; A2A2T1; O95392;
DE   RecName: Full=Negative elongation factor A;
DE            Short=NELF-A;
DE   AltName: Full=Wolf-Hirschhorn syndrome candidate 2 protein;
GN   Name=NELFA; Synonyms=WHSC2; ORFNames=P/OKcl.15;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NELFD_HUMAN             Reviewed;         590 AA.
AC   Q8IXH7; B4DE06; Q9BYL2; Q9H405; Q9H888; Q9H8T3; Q9NVX5; Q9P029;
AC   Q9UGN1; Q9UGN2; Q9UGN3;
DE   RecName: Full=Negative elongation factor C/D;
DE            Short=NELF-C/D;
DE   AltName: Full=TH1-like protein;
GN   Name=NELFCD; Synonyms=NELFD, TH1, TH1L; ORFNames=HSPC130;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NELFB_HUMAN             Reviewed;         580 AA.
AC   Q8WX92; A2BFA3; Q96EW5; Q9H9R4; Q9ULN8; Q9Y3W0;
DE   RecName: Full=Negative elongation factor B;
DE            Short=NELF-B;
DE   AltName: Full=Cofactor of BRCA1;
GN   Name=NELFB; Synonyms=COBRA1, KIAA1182;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NELFE_HUMAN             Reviewed;         380 AA.
AC   P18615; A2BE08; Q5JP74; Q5JP75; Q96F56; Q9NPK2;
DE   RecName: Full=Negative elongation factor E;
DE            Short=NELF-E;
DE   AltName: Full=RNA-binding protein RD;
GN   Name=NELFE; Synonyms=RD, RDBP;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NELL1_HUMAN             Reviewed;         810 AA.
AC   Q92832; B2CKC1; Q4VB90; Q4VB91; Q6NSY8; Q9Y472;
DE   RecName: Full=Protein kinase C-binding protein NELL1;
DE   AltName: Full=NEL-like protein 1;
DE   AltName: Full=Nel-related protein 1;
DE   Flags: Precursor;
GN   Name=NELL1; Synonyms=NRP1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:2000599; P:negative regulation of cyclin catabolic process; IDA:UniProtKB.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:UniProtKB.
//
ID   NELL2_HUMAN             Reviewed;         816 AA.
AC   Q99435; B7Z2U7; B7Z5Q4; B7Z9J5; B7Z9U3; Q96JS2;
DE   RecName: Full=Protein kinase C-binding protein NELL2;
DE   AltName: Full=NEL-like protein 2;
DE   AltName: Full=Nel-related protein 2;
DE   Flags: Precursor;
GN   Name=NELL2; Synonyms=NRP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NEMF_HUMAN              Reviewed;        1076 AA.
AC   O60524; A0JLQ3; B3KSK1; B4DDL3; B4DHA9; B4E3F3; Q32Q66; Q8WW70;
AC   Q9NWG1;
DE   RecName: Full=Nuclear export mediator factor NEMF;
DE   AltName: Full=Antigen NY-CO-1;
DE   AltName: Full=Serologically defined colon cancer antigen 1;
GN   Name=NEMF; Synonyms=SDCCAG1;
DR   GO; GO:0051168; P:nuclear export; IMP:UniProtKB.
//
ID   NEMO_HUMAN              Reviewed;         419 AA.
AC   Q9Y6K9; Q7LBY6; Q7Z7F1;
DE   RecName: Full=NF-kappa-B essential modulator;
DE            Short=NEMO;
DE   AltName: Full=FIP-3;
DE   AltName: Full=IkB kinase-associated protein 1;
DE            Short=IKKAP1;
DE   AltName: Full=Inhibitor of nuclear factor kappa-B kinase subunit gamma;
DE            Short=I-kappa-B kinase subunit gamma;
DE            Short=IKK-gamma;
DE            Short=IKKG;
DE            Short=IkB kinase subunit gamma;
DE   AltName: Full=NF-kappa-B essential modifier;
GN   Name=IKBKG; Synonyms=FIP3, NEMO;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NENF_HUMAN              Reviewed;         172 AA.
AC   Q9UMX5; A1KYQ8; Q53FZ6; Q5TM90;
DE   RecName: Full=Neudesin;
DE   AltName: Full=Cell immortalization-related protein 2;
DE   AltName: Full=Neuron-derived neurotrophic factor;
DE   AltName: Full=Secreted protein of unknown function;
DE            Short=SPUF protein;
DE   Flags: Precursor;
GN   Name=NENF; Synonyms=CIR2, SPUF;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
//
ID   NEO1_HUMAN              Reviewed;        1461 AA.
AC   Q92859; B7ZKM9; B7ZKN0; O00340; Q17RX1;
DE   RecName: Full=Neogenin;
DE   AltName: Full=Immunoglobulin superfamily DCC subclass member 2;
DE   Flags: Precursor;
GN   Name=NEO1; Synonyms=IGDCC2, NGN;
DR   GO; GO:0004872; F:receptor activity; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0055072; P:iron ion homeostasis; IGI:MGI.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   NEP1_HUMAN              Reviewed;         244 AA.
AC   Q92979; O00675; O00726;
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase NEP1;
DE            EC=2.1.1.-;
DE   AltName: Full=18S rRNA (pseudouridine-N1-)-methyltransferase NEP1;
DE   AltName: Full=18S rRNA Psi1248 methyltransferase;
DE   AltName: Full=Nucleolar protein EMG1 homolog;
DE   AltName: Full=Protein C2f;
DE   AltName: Full=Ribosome biogenesis protein NEP1;
GN   Name=EMG1; Synonyms=C2F;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0070037; F:rRNA (pseudouridine) methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; ISS:UniProtKB.
DR   GO; GO:0031167; P:rRNA methylation; IDA:GOC.
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
//
ID   NEPR1_HUMAN             Reviewed;         125 AA.
AC   Q8N9A8; Q4G1A9; Q5H9V0; Q8NE06;
DE   RecName: Full=Nuclear envelope phosphatase-regulatory subunit 1;
DE            Short=NEP1-R1;
DE   AltName: Full=Transmembrane protein 188;
GN   Name=CNEP1R1; Synonyms=C16orf69, TMEM188;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; IGI:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
//
ID   NEP_HUMAN               Reviewed;         750 AA.
AC   P08473; A8K6U6; D3DNJ9; Q3MIX4;
DE   RecName: Full=Neprilysin;
DE            EC=3.4.24.11;
DE   AltName: Full=Atriopeptidase;
DE   AltName: Full=Common acute lymphocytic leukemia antigen;
DE            Short=CALLA;
DE   AltName: Full=Enkephalinase;
DE   AltName: Full=Neutral endopeptidase 24.11;
DE            Short=NEP;
DE            Short=Neutral endopeptidase;
DE   AltName: Full=Skin fibroblast elastase;
DE            Short=SFE;
DE   AltName: CD_antigen=CD10;
GN   Name=MME; Synonyms=EPN;
DR   GuidetoPHARMACOLOGY; 1611; -.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0002003; P:angiotensin maturation; TAS:Reactome.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IDA:UniProtKB.
DR   GO; GO:0071492; P:cellular response to UV-A; IDA:UniProtKB.
DR   GO; GO:0071493; P:cellular response to UV-B; IDA:UniProtKB.
DR   GO; GO:0046449; P:creatinine metabolic process; IMP:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEP:UniProtKB.
DR   GO; GO:0006518; P:peptide metabolic process; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0090399; P:replicative senescence; IEP:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
//
ID   NEST_HUMAN              Reviewed;        1621 AA.
AC   P48681; O00552; Q3LIF5; Q5SYZ6;
DE   RecName: Full=Nestin;
GN   Name=NES; ORFNames=Nbla00170;
DR   GO; GO:0019215; F:intermediate filament binding; ISS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0048858; P:cell projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0031076; P:embryonic camera-type eye development; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:DFLAT.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0030844; P:positive regulation of intermediate filament depolymerization; ISS:UniProtKB.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0072089; P:stem cell proliferation; IMP:DFLAT.
//
ID   NET1_HUMAN              Reviewed;         604 AA.
AC   O95631; E9KL51;
DE   RecName: Full=Netrin-1;
DE   AltName: Full=Epididymis tissue protein Li 131P;
DE   Flags: Precursor;
GN   Name=NTN1; Synonyms=NTN1L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033564; P:anterior/posterior axon guidance; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0040023; P:establishment of nucleus localization; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060603; P:mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
//
ID   NET3_HUMAN              Reviewed;         580 AA.
AC   O00634;
DE   RecName: Full=Netrin-3;
DE   AltName: Full=Netrin-2-like protein;
DE   Flags: Precursor;
GN   Name=NTN3; Synonyms=NTN2L;
DR   GO; GO:0007411; P:axon guidance; NAS:UniProtKB.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
//
ID   NET4_HUMAN              Reviewed;         628 AA.
AC   Q9HB63; B2RNC2; Q658K9; Q7L3F1; Q7L9D6; Q7Z5B6; Q9BZP1; Q9NT44;
AC   Q9P133;
DE   RecName: Full=Netrin-4;
DE   AltName: Full=Beta-netrin;
DE   AltName: Full=Hepar-derived netrin-like protein;
DE   Flags: Precursor;
GN   Name=NTN4;
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0016322; P:neuron remodeling; IEA:Ensembl.
DR   GO; GO:0060668; P:regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling; IEA:Ensembl.
//
ID   NET5_HUMAN              Reviewed;         489 AA.
AC   Q8WTR8; Q8N4X9; Q8WU63;
DE   RecName: Full=Netrin-5;
DE   AltName: Full=Netrin-1-like protein;
DE   Flags: Precursor;
GN   Name=NTN5;
//
ID   NETO1_HUMAN             Reviewed;         533 AA.
AC   Q8TDF5; Q86W85; Q8ND78; Q8TDF4;
DE   RecName: Full=Neuropilin and tolloid-like protein 1;
DE   AltName: Full=Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1;
DE   Flags: Precursor;
GN   Name=NETO1; Synonyms=BTCL1;
DR   GO; GO:0007613; P:memory; ISS:UniProtKB.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0008542; P:visual learning; ISS:UniProtKB.
//
ID   NETO2_HUMAN             Reviewed;         525 AA.
AC   Q8NC67; J3KNF1; Q7Z381; Q8ND51; Q96SP4; Q9NVY8;
DE   RecName: Full=Neuropilin and tolloid-like protein 2;
DE   AltName: Full=Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2;
DE   Flags: Precursor;
GN   Name=NETO2; Synonyms=BTCL2; ORFNames=UNQ1926/PRO4401;
DR   GO; GO:2000312; P:regulation of kainate selective glutamate receptor activity; IEA:InterPro.
//
ID   NETR_HUMAN              Reviewed;         875 AA.
AC   P56730; Q9UP16;
DE   RecName: Full=Neurotrypsin;
DE            EC=3.4.21.-;
DE   AltName: Full=Leydin;
DE   AltName: Full=Motopsin;
DE   AltName: Full=Serine protease 12;
DE   Flags: Precursor;
GN   Name=PRSS12;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006887; P:exocytosis; ISS:UniProtKB.
DR   GO; GO:0031638; P:zymogen activation; IEA:Ensembl.
//
ID   NEU1B_HUMAN             Reviewed;         555 AA.
AC   A8MQ27; C9DQJ5; C9DQJ6; C9DQJ7;
DE   RecName: Full=E3 ubiquitin-protein ligase NEURL1B;
DE            EC=6.3.2.-;
DE   AltName: Full=Neuralized-2;
DE            Short=NEUR2;
DE   AltName: Full=Neuralized-like protein 1B;
DE   AltName: Full=Neuralized-like protein 3;
GN   Name=NEURL1B; Synonyms=NEURL3;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   NEU1_HUMAN              Reviewed;         125 AA.
AC   P01178; Q3MIG0;
DE   RecName: Full=Oxytocin-neurophysin 1;
DE            Short=OT-NPI;
DE   Contains:
DE     RecName: Full=Oxytocin;
DE     AltName: Full=Ocytocin;
DE   Contains:
DE     RecName: Full=Neurophysin 1;
DE   Flags: Precursor;
GN   Name=OXT; Synonyms=OT;
DR   GO; GO:0042756; P:drinking behavior; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0042538; P:hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0060179; P:male mating behavior; IEA:Ensembl.
DR   GO; GO:0002125; P:maternal aggressive behavior; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0060455; P:negative regulation of gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0035811; P:negative regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0045925; P:positive regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0060450; P:positive regulation of hindgut contraction; IEA:Ensembl.
DR   GO; GO:0010701; P:positive regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0060406; P:positive regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0032308; P:positive regulation of prostaglandin secretion; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045472; P:response to ether; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0034695; P:response to prostaglandin E; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0009744; P:response to sucrose; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0042713; P:sperm ejaculation; IEA:Ensembl.
//
ID   NEU2_HUMAN              Reviewed;         164 AA.
AC   P01185; A0AV35; O14935;
DE   RecName: Full=Vasopressin-neurophysin 2-copeptin;
DE   AltName: Full=AVP-NPII;
DE   Contains:
DE     RecName: Full=Arg-vasopressin;
DE     AltName: Full=Arginine-vasopressin;
DE   Contains:
DE     RecName: Full=Neurophysin 2;
DE     AltName: Full=Neurophysin-II;
DE   Contains:
DE     RecName: Full=Copeptin;
DE   Flags: Precursor;
GN   Name=AVP; Synonyms=ARVP, VP;
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IDA:UniProtKB.
DR   GO; GO:0031894; F:V1A vasopressin receptor binding; IPI:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0042538; P:hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0002125; P:maternal aggressive behavior; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007621; P:negative regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0051970; P:negative regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0043084; P:penile erection; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032849; P:positive regulation of cellular pH reduction; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0014049; P:positive regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0070528; P:protein kinase C signaling; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0035813; P:regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0042310; P:vasoconstriction; IEA:UniProtKB-KW.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   NEUA_HUMAN              Reviewed;         434 AA.
AC   Q8NFW8; Q96AX5; Q9NQZ0;
DE   RecName: Full=N-acylneuraminate cytidylyltransferase;
DE            EC=2.7.7.43;
DE   AltName: Full=CMP-N-acetylneuraminic acid synthase;
DE            Short=CMP-NeuNAc synthase;
GN   Name=CMAS;
DR   GO; GO:0008781; F:N-acylneuraminate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0006054; P:N-acetylneuraminate metabolic process; IEA:UniProtKB-UniPathway.
//
ID   NEUG_HUMAN              Reviewed;          78 AA.
AC   Q92686;
DE   RecName: Full=Neurogranin;
DE            Short=Ng;
DE   AltName: Full=RC3;
DE   Contains:
DE     RecName: Full=NEUG(55-78);
GN   Name=NRGN;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NEUFC_HUMAN             Reviewed;         264 AA.
AC   Q8WUJ1; B2R7R6; D3DTJ9; I3L1K2;
DE   RecName: Full=Neuferricin;
DE   AltName: Full=Cytochrome b5 domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=CYB5D2;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   NEUL1_HUMAN             Reviewed;         574 AA.
AC   O76050; Q5TDR2; Q5TDR3; Q8TAN0; Q9H463;
DE   RecName: Full=E3 ubiquitin-protein ligase NEURL1;
DE            EC=6.3.2.-;
DE   AltName: Full=Neuralized-like protein 1A;
DE            Short=h-neu;
DE            Short=h-neuralized 1;
DE   AltName: Full=RING finger protein 67;
GN   Name=NEURL1; Synonyms=NEURL, NEURL1A, RNF67;
DR   GO; GO:0045183; F:translation factor activity, non-nucleic acid binding; ISS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0007288; P:sperm axoneme assembly; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
//
ID   NEUL2_HUMAN             Reviewed;         285 AA.
AC   Q9BR09; Q3KR34;
DE   RecName: Full=Neuralized-like protein 2;
GN   Name=NEURL2; Synonyms=C20orf163;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
//
ID   NEUL4_HUMAN             Reviewed;        1562 AA.
AC   Q96JN8; Q6GPI8; Q96IU9; Q9H0B0;
DE   RecName: Full=Neuralized-like protein 4;
GN   Name=NEURL4; Synonyms=KIAA1787;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NEUL3_HUMAN             Reviewed;         262 AA.
AC   Q96EH8;
DE   RecName: Full=E3 ubiquitin-protein ligase NEURL3;
DE            EC=6.3.2.-;
DE   AltName: Full=Lung-inducible neuralized-related C3CH4 RING domain protein;
DE   AltName: Full=Neuralized-like protein 3;
GN   Name=NEURL3; Synonyms=LINCR;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   NEUL_HUMAN              Reviewed;         704 AA.
AC   Q9BYT8; Q9ULJ4;
DE   RecName: Full=Neurolysin, mitochondrial;
DE            EC=3.4.24.16;
DE   AltName: Full=Angiotensin-binding protein;
DE   AltName: Full=Microsomal endopeptidase;
DE            Short=MEP;
DE   AltName: Full=Mitochondrial oligopeptidase M;
DE   AltName: Full=Neurotensin endopeptidase;
DE   Flags: Precursor;
GN   Name=NLN; Synonyms=AGTBP, KIAA1226;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
//
ID   NEUM_HUMAN              Reviewed;         238 AA.
AC   P17677; A8K0Y4;
DE   RecName: Full=Neuromodulin;
DE   AltName: Full=Axonal membrane protein GAP-43;
DE   AltName: Full=Growth-associated protein 43;
DE   AltName: Full=Neural phosphoprotein B-50;
DE   AltName: Full=pp46;
GN   Name=GAP43;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016198; P:axon choice point recognition; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
//
ID   NEUR1_HUMAN             Reviewed;         415 AA.
AC   Q99519;
DE   RecName: Full=Sialidase-1;
DE            EC=3.2.1.18;
DE   AltName: Full=Acetylneuraminyl hydrolase;
DE   AltName: Full=G9 sialidase;
DE   AltName: Full=Lysosomal sialidase;
DE   AltName: Full=N-acetyl-alpha-neuraminidase 1;
DE   Flags: Precursor;
GN   Name=NEU1; Synonyms=NANH;
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   NEUR2_HUMAN             Reviewed;         380 AA.
AC   Q9Y3R4; Q3KNW4; Q6NTB4;
DE   RecName: Full=Sialidase-2;
DE            EC=3.2.1.18;
DE   AltName: Full=Cytosolic sialidase;
DE   AltName: Full=N-acetyl-alpha-neuraminidase 2;
GN   Name=NEU2;
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IDA:UniProtKB.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006689; P:ganglioside catabolic process; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   NEUR3_HUMAN             Reviewed;         428 AA.
AC   Q9UQ49; A8K327; Q9NQE1;
DE   RecName: Full=Sialidase-3;
DE            EC=3.2.1.18;
DE   AltName: Full=Ganglioside sialidase;
DE   AltName: Full=Membrane sialidase;
DE   AltName: Full=N-acetyl-alpha-neuraminidase 3;
GN   Name=NEU3;
DR   GO; GO:0016997; F:alpha-sialidase activity; IDA:MGI.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; ISS:UniProtKB.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; ISS:UniProtKB.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IDA:MGI.
DR   GO; GO:0006689; P:ganglioside catabolic process; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   NEUR4_HUMAN             Reviewed;         484 AA.
AC   Q8WWR8; A8K056; J3KNJ5; Q96D64;
DE   RecName: Full=Sialidase-4;
DE            EC=3.2.1.18;
DE   AltName: Full=N-acetyl-alpha-neuraminidase 4;
GN   Name=NEU4; ORFNames=LP5125;
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006689; P:ganglioside catabolic process; IDA:UniProtKB.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   NEUS_HUMAN              Reviewed;         410 AA.
AC   Q99574; A8K217; D3DNP1; Q6AHZ4;
DE   RecName: Full=Neuroserpin;
DE   AltName: Full=Peptidase inhibitor 12;
DE            Short=PI-12;
DE   AltName: Full=Serpin I1;
DE   Flags: Precursor;
GN   Name=SERPINI1; Synonyms=PI12;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   NEUT_HUMAN              Reviewed;         170 AA.
AC   P30990;
DE   RecName: Full=Neurotensin/neuromedin N;
DE   Contains:
DE     RecName: Full=Large neuromedin N;
DE     AltName: Full=NmN-125;
DE   Contains:
DE     RecName: Full=Neuromedin N;
DE              Short=NN;
DE              Short=NmN;
DE   Contains:
DE     RecName: Full=Neurotensin;
DE              Short=NT;
DE   Contains:
DE     RecName: Full=Tail peptide;
DE   Flags: Precursor;
GN   Name=NTS;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050880; P:regulation of blood vessel size; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   NEXN_HUMAN              Reviewed;         675 AA.
AC   Q0ZGT2; A0PJ84; B4DPZ7; Q0D2H2; Q14CC2; Q14CC3; Q16081; Q7Z2X0;
AC   Q96DL0; Q9Y2V1;
DE   RecName: Full=Nexilin;
DE   AltName: Full=F-actin-binding protein;
DE   AltName: Full=Nelin;
GN   Name=NEXN;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IBA:RefGenome.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:UniProtKB.
DR   GO; GO:0048739; P:cardiac muscle fiber development; IBA:RefGenome.
DR   GO; GO:0006468; P:protein phosphorylation; IBA:GOC.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; IEP:UniProtKB.
//
ID   NF1_HUMAN               Reviewed;        2839 AA.
AC   P21359; O00662; Q14284; Q14930; Q14931; Q9UMK3;
DE   RecName: Full=Neurofibromin;
DE   AltName: Full=Neurofibromatosis-related protein NF-1;
DE   Contains:
DE     RecName: Full=Neurofibromin truncated;
GN   Name=NF1;
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:UniProtKB.
DR   GO; GO:0008429; F:phosphatidylethanolamine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:HGNC.
DR   GO; GO:0030325; P:adrenal gland development; ISS:HGNC.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:HGNC.
DR   GO; GO:0007420; P:brain development; ISS:HGNC.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; ISS:HGNC.
DR   GO; GO:0007154; P:cell communication; ISS:HGNC.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:HGNC.
DR   GO; GO:0050890; P:cognition; IMP:HGNC.
DR   GO; GO:0030199; P:collagen fibril organization; ISS:HGNC.
DR   GO; GO:0030198; P:extracellular matrix organization; ISS:HGNC.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0021897; P:forebrain astrocyte development; ISS:HGNC.
DR   GO; GO:0048853; P:forebrain morphogenesis; ISS:HGNC.
DR   GO; GO:0007507; P:heart development; ISS:HGNC.
DR   GO; GO:0001889; P:liver development; ISS:HGNC.
DR   GO; GO:0000165; P:MAPK cascade; ISS:HGNC.
DR   GO; GO:0001656; P:metanephros development; ISS:HGNC.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; ISS:HGNC.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:MGI.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:HGNC.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; ISS:HGNC.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; ISS:HGNC.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; ISS:HGNC.
DR   GO; GO:0046929; P:negative regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:HGNC.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:HGNC.
DR   GO; GO:0035021; P:negative regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0042992; P:negative regulation of transcription factor import into nucleus; ISS:HGNC.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:HGNC.
DR   GO; GO:0007422; P:peripheral nervous system development; ISS:HGNC.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; ISS:HGNC.
DR   GO; GO:0043473; P:pigmentation; ISS:HGNC.
DR   GO; GO:0045762; P:positive regulation of adenylate cyclase activity; ISS:HGNC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:HGNC.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:HGNC.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; ISS:HGNC.
DR   GO; GO:0045765; P:regulation of angiogenesis; IMP:HGNC.
DR   GO; GO:0043535; P:regulation of blood vessel endothelial cell migration; IMP:HGNC.
DR   GO; GO:0045124; P:regulation of bone resorption; ISS:HGNC.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; ISS:HGNC.
DR   GO; GO:0045685; P:regulation of glial cell differentiation; ISS:HGNC.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; IMP:HGNC.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; ISS:HGNC.
DR   GO; GO:0014044; P:Schwann cell development; ISS:HGNC.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; ISS:HGNC.
DR   GO; GO:0021510; P:spinal cord development; ISS:HGNC.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:HGNC.
DR   GO; GO:0008542; P:visual learning; ISS:HGNC.
DR   GO; GO:0042060; P:wound healing; ISS:HGNC.
//
ID   NF2IP_HUMAN             Reviewed;         419 AA.
AC   Q8NCF5; B7Z4G5; Q66K34; Q6NVK1; Q8NFR2; Q96ST9;
DE   RecName: Full=NFATC2-interacting protein;
DE   AltName: Full=45 kDa NF-AT-interacting protein;
DE            Short=45 kDa NFAT-interacting protein;
DE   AltName: Full=Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein;
GN   Name=NFATC2IP; Synonyms=NIP45;
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   NF2L1_HUMAN             Reviewed;         772 AA.
AC   Q14494; D3DTU3; D3DTU5; Q12877; Q96FN6;
DE   RecName: Full=Nuclear factor erythroid 2-related factor 1;
DE            Short=NF-E2-related factor 1;
DE            Short=NFE2-related factor 1;
DE   AltName: Full=Locus control region-factor 1;
DE   AltName: Full=Nuclear factor, erythroid derived 2, like 1;
DE   AltName: Full=Transcription factor 11;
DE            Short=TCF-11;
DE   AltName: Full=Transcription factor HBZ17;
DE   AltName: Full=Transcription factor LCR-F1;
GN   Name=NFE2L1; Synonyms=HBZ17, NRF1, TCF11;
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NF2L2_HUMAN             Reviewed;         605 AA.
AC   Q16236; B2RBU2; B4E338; E9PGJ7; Q53RW6; Q59HH2; Q96F71;
DE   RecName: Full=Nuclear factor erythroid 2-related factor 2;
DE            Short=NF-E2-related factor 2;
DE            Short=NFE2-related factor 2;
DE   AltName: Full=HEBP1;
DE   AltName: Full=Nuclear factor, erythroid derived 2, like 2;
GN   Name=NFE2L2; Synonyms=NRF2;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IMP:BHF-UCL.
DR   GO; GO:0071499; P:cellular response to laminar fluid shear stress; IMP:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IMP:BHF-UCL.
DR   GO; GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:Ensembl.
DR   GO; GO:2000121; P:regulation of removal of superoxide radicals; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NF2L3_HUMAN             Reviewed;         694 AA.
AC   Q9Y4A8; Q6NUS0; Q7Z498; Q86UJ4; Q86VR5; Q9UQA4;
DE   RecName: Full=Nuclear factor erythroid 2-related factor 3;
DE            Short=NF-E2-related factor 3;
DE            Short=NFE2-related factor 3;
DE   AltName: Full=Nuclear factor, erythroid derived 2, like 3;
GN   Name=NFE2L3; Synonyms=NRF3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFAC1_HUMAN             Reviewed;         943 AA.
AC   O95644; B5B2M4; B5B2M5; B5B2M6; B5B2M7; B5B2M8; B5B2M9; B5B2N1;
AC   Q12865; Q15793; Q2M1S3;
DE   RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 1;
DE            Short=NF-ATc1;
DE            Short=NFATc1;
DE   AltName: Full=NFAT transcription complex cytosolic component;
DE            Short=NF-ATc;
DE            Short=NFATc;
GN   Name=NFATC1; Synonyms=NFAT2, NFATC;
DR   GO; GO:0005528; F:FK506 binding; TAS:ProtInc.
DR   GO; GO:0048273; F:mitogen-activated protein kinase p38 binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFAC2_HUMAN             Reviewed;         925 AA.
AC   Q13469; B5B2N8; B5B2N9; B5B2P2; B5B2P3; Q13468; Q5TFW7; Q5TFW8;
AC   Q9NPX6; Q9NQH3; Q9UJR2;
DE   RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 2;
DE            Short=NF-ATc2;
DE            Short=NFATc2;
DE   AltName: Full=NFAT pre-existing subunit;
DE            Short=NF-ATp;
DE   AltName: Full=T-cell transcription factor NFAT1;
GN   Name=NFATC2; Synonyms=NFAT1, NFATP;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NFAC3_HUMAN             Reviewed;        1075 AA.
AC   Q12968; O75211; Q14516; Q99840; Q99841; Q99842;
DE   RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 3;
DE            Short=NF-ATc3;
DE            Short=NFATc3;
DE   AltName: Full=NFATx;
DE   AltName: Full=T-cell transcription factor NFAT4;
DE            Short=NF-AT4;
GN   Name=NFATC3; Synonyms=NFAT4;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045333; P:cellular respiration; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0055001; P:muscle cell development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFAC4_HUMAN             Reviewed;         902 AA.
AC   Q14934; B4DDG5; B4DY55; B5B2U7; B5B2U8; B5B2U9; B5B2V0; B5B2V1;
AC   B5B2V2; B5B2V3; B5B2V4; B5B2V5; B5B2V7; B5B2V8; B5B2V9; B5B2W0;
AC   B5B2W1; B5B2W2; B5B2W3; B5B2W4; B5B2W5; B5B2W6; B5B2W7; B5B2W8;
AC   B5B2W9; B5B2X0; Q7Z598; Q96H68;
DE   RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 4;
DE            Short=NF-ATc4;
DE            Short=NFATc4;
DE   AltName: Full=T-cell transcription factor NFAT3;
DE            Short=NF-AT3;
GN   Name=NFATC4; Synonyms=NFAT3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0045333; P:cellular respiration; IEA:Ensembl.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0055001; P:muscle cell development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFAM1_HUMAN             Reviewed;         270 AA.
AC   Q8NET5; B0QYD0; Q20WL2; Q5JZ96; Q8IUY8; Q8TEM8;
DE   RecName: Full=NFAT activation molecule 1;
DE   AltName: Full=Calcineurin/NFAT-activating ITAM-containing protein;
DE   AltName: Full=NFAT-activating protein with ITAM motif 1;
DE   Flags: Precursor;
GN   Name=NFAM1; Synonyms=CNAIP;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:HGNC.
DR   GO; GO:0030183; P:B cell differentiation; ISS:HGNC.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; NAS:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:HGNC.
DR   GO; GO:0001819; P:positive regulation of cytokine production; NAS:HGNC.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:HGNC.
DR   GO; GO:0045577; P:regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:HGNC.
//
ID   NFASC_HUMAN             Reviewed;        1347 AA.
AC   O94856; B2RNN8; B3KQZ1; B5MDP6; B5MDR6; B7ZMD8; Q149P5; Q5T2F0;
AC   Q5T2F1; Q5T2F2; Q5T2F3; Q5T2F4; Q5T2F5; Q5T2F6; Q5T2F7; Q5T2F9;
AC   Q5T2G0; Q5W9F8; Q68DH3; Q6ZQV6; Q7Z3K1; Q96HT1; Q96K50;
DE   RecName: Full=Neurofascin;
DE   Flags: Precursor;
GN   Name=NFASC; Synonyms=KIAA0756;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; IEA:Ensembl.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; ISS:BHF-UCL.
DR   GO; GO:0030913; P:paranodal junction assembly; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; ISS:BHF-UCL.
DR   GO; GO:0071205; P:protein localization to juxtaparanode region of axon; IEA:Ensembl.
DR   GO; GO:0002175; P:protein localization to paranode region of axon; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   NFH_HUMAN               Reviewed;        1026 AA.
AC   P12036; B4DYY4; Q96HF8; Q9UJS7; Q9UQ14;
DE   RecName: Full=Neurofilament heavy polypeptide;
DE            Short=NF-H;
DE   AltName: Full=200 kDa neurofilament protein;
DE   AltName: Full=Neurofilament triplet H protein;
GN   Name=NEFH; Synonyms=KIAA0845, NFH;
DR   GO; GO:0045502; F:dynein binding; TAS:BHF-UCL.
DR   GO; GO:0019894; F:kinesin binding; TAS:BHF-UCL.
DR   GO; GO:0008017; F:microtubule binding; TAS:BHF-UCL.
DR   GO; GO:0030674; F:protein binding, bridging; ISS:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; ISS:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; IMP:BHF-UCL.
DR   GO; GO:0061564; P:axon development; IMP:BHF-UCL.
DR   GO; GO:0007409; P:axonogenesis; TAS:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0030031; P:cell projection assembly; TAS:BHF-UCL.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0033693; P:neurofilament bundle assembly; IMP:BHF-UCL.
DR   GO; GO:0048936; P:peripheral nervous system neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:1902513; P:regulation of organelle transport along microtubule; IMP:BHF-UCL.
//
ID   NFE4_HUMAN              Reviewed;         179 AA.
AC   Q86UQ8;
DE   RecName: Full=Transcription factor NF-E4;
GN   Name=NFE4;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NFAT5_HUMAN             Reviewed;        1531 AA.
AC   O94916; A2RRB4; A6H8V5; E9PHR7; O95693; Q7LA65; Q969Q8; Q96QH3;
AC   Q9UN18;
DE   RecName: Full=Nuclear factor of activated T-cells 5;
DE            Short=NF-AT5;
DE   AltName: Full=T-cell transcription factor NFAT5;
DE   AltName: Full=Tonicity-responsive enhancer-binding protein;
DE            Short=TonE-binding protein;
DE            Short=TonEBP;
GN   Name=NFAT5; Synonyms=KIAA0827, TONEBP;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0070884; P:regulation of calcineurin-NFAT signaling cascade; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFE2_HUMAN              Reviewed;         373 AA.
AC   Q16621; Q07720; Q6ICV9;
DE   RecName: Full=Transcription factor NF-E2 45 kDa subunit;
DE   AltName: Full=Leucine zipper protein NF-E2;
DE   AltName: Full=Nuclear factor, erythroid-derived 2 45 kDa subunit;
DE   AltName: Full=p45 NF-E2;
GN   Name=NFE2;
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; TAS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0050699; F:WW domain binding; IPI:BHF-UCL.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0007599; P:hemostasis; TAS:ProtInc.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0034242; P:negative regulation of syncytium formation by plasma membrane fusion; IEA:Ensembl.
DR   GO; GO:0006337; P:nucleosome disassembly; TAS:BHF-UCL.
DR   GO; GO:2000758; P:positive regulation of peptidyl-lysine acetylation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:BHF-UCL.
//
ID   NFIA_HUMAN              Reviewed;         509 AA.
AC   Q12857; B4DRJ3; B4DS53; F5H0R0; F8W8W3; Q8TA97; Q9H3X9; Q9P2A9;
DE   RecName: Full=Nuclear factor 1 A-type;
DE            Short=NF1-A;
DE            Short=Nuclear factor 1/A;
DE   AltName: Full=CCAAT-box-binding transcription factor;
DE            Short=CTF;
DE   AltName: Full=Nuclear factor I/A;
DE            Short=NF-I/A;
DE            Short=NFI-A;
DE   AltName: Full=TGGCA-binding protein;
GN   Name=NFIA; Synonyms=KIAA1439;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; NAS:UniProtKB.
//
ID   NFIB_HUMAN              Reviewed;         420 AA.
AC   O00712; G3V1P1; H7BYE8; O00166; Q12858; Q5VW29; Q63HM5; Q6ZNF9;
AC   Q96J45;
DE   RecName: Full=Nuclear factor 1 B-type;
DE            Short=NF1-B;
DE            Short=Nuclear factor 1/B;
DE   AltName: Full=CCAAT-box-binding transcription factor;
DE            Short=CTF;
DE   AltName: Full=Nuclear factor I/B;
DE            Short=NF-I/B;
DE            Short=NFI-B;
DE   AltName: Full=TGGCA-binding protein;
GN   Name=NFIB;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0021960; P:anterior commissure morphogenesis; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0060486; P:Clara cell differentiation; ISS:UniProtKB.
DR   GO; GO:0071679; P:commissural neuron axon guidance; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0010001; P:glial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0061141; P:lung ciliated cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:2000795; P:negative regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.
DR   GO; GO:2000791; P:negative regulation of mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0021740; P:principal sensory nucleus of trigeminal nerve development; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0060509; P:Type I pneumocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0060510; P:Type II pneumocyte differentiation; ISS:UniProtKB.
//
ID   NFIC_HUMAN              Reviewed;         508 AA.
AC   P08651; A8K1H0; B7Z4U5; B7Z9C3; K7EMU1; P08652; Q14932; Q9UPJ3;
AC   Q9UPJ9; Q9UPK0; Q9UPK1;
DE   RecName: Full=Nuclear factor 1 C-type;
DE            Short=NF1-C;
DE            Short=Nuclear factor 1/C;
DE   AltName: Full=CCAAT-box-binding transcription factor;
DE            Short=CTF;
DE   AltName: Full=Nuclear factor I/C;
DE            Short=NF-I/C;
DE            Short=NFI-C;
DE   AltName: Full=TGGCA-binding protein;
GN   Name=NFIC; Synonyms=NFI;
DR   GO; GO:0001159; F:core promoter proximal region DNA binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFIL3_HUMAN             Reviewed;         462 AA.
AC   Q16649; B2R9Y8; Q14211; Q6FGQ8; Q96HS0;
DE   RecName: Full=Nuclear factor interleukin-3-regulated protein;
DE   AltName: Full=E4 promoter-binding protein 4;
DE   AltName: Full=Interleukin-3 promoter transcriptional activator;
DE   AltName: Full=Interleukin-3-binding protein 1;
DE   AltName: Full=Transcriptional activator NF-IL3A;
GN   Name=NFIL3; Synonyms=E4BP4, IL3BP1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFIP1_HUMAN             Reviewed;         221 AA.
AC   Q9BT67; B2RDB8; D3DQF0; Q658T8; Q8N2E3; Q8N2F9;
DE   RecName: Full=NEDD4 family-interacting protein 1;
DE   AltName: Full=Breast cancer-associated protein SGA-1M;
DE   AltName: Full=NEDD4 WW domain-binding protein 5;
DE   AltName: Full=Putative MAPK-activating protein PM13;
DE   AltName: Full=Putative NF-kappa-B-activating protein 164;
DE   AltName: Full=Putative NFKB and MAPK-activating protein;
GN   Name=NDFIP1; Synonyms=N4WBP5; ORFNames=PSEC0192, PSEC0223;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032713; P:negative regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0048294; P:negative regulation of isotype switching to IgE isotypes; IEA:Ensembl.
DR   GO; GO:0051224; P:negative regulation of protein transport; IMP:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0032410; P:negative regulation of transporter activity; IMP:UniProtKB.
DR   GO; GO:0002829; P:negative regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0048302; P:regulation of isotype switching to IgG isotypes; IEA:Ensembl.
DR   GO; GO:0045619; P:regulation of lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002761; P:regulation of myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:Ensembl.
//
ID   NFIP2_HUMAN             Reviewed;         336 AA.
AC   Q9NV92; Q7Z2H3; Q7Z428; Q8TAR3; Q9ULQ5;
DE   RecName: Full=NEDD4 family-interacting protein 2;
DE   AltName: Full=NEDD4 WW domain-binding protein 5A;
DE   AltName: Full=Putative MAPK-activating protein PM04/PM05/PM06/PM07;
DE   AltName: Full=Putative NF-kappa-B-activating protein 413;
GN   Name=NDFIP2; Synonyms=KIAA1165, N4WBP5A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IPI:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0051224; P:negative regulation of protein transport; IMP:UniProtKB.
DR   GO; GO:0032410; P:negative regulation of transporter activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   NFIX_HUMAN              Reviewed;         502 AA.
AC   Q14938; O60413; Q0VG09; Q12859; Q13050; Q13052; Q5U094; Q9UPH1;
AC   Q9Y6R8;
DE   RecName: Full=Nuclear factor 1 X-type;
DE            Short=NF1-X;
DE            Short=Nuclear factor 1/X;
DE   AltName: Full=CCAAT-box-binding transcription factor;
DE            Short=CTF;
DE   AltName: Full=Nuclear factor I/X;
DE            Short=NF-I/X;
DE            Short=NFI-X;
DE   AltName: Full=TGGCA-binding protein;
GN   Name=NFIX;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0048708; P:astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFKB1_HUMAN             Reviewed;         968 AA.
AC   P19838; A8K5Y5; B3KVE8; Q68D84; Q86V43; Q8N4X7; Q9NZC0;
DE   RecName: Full=Nuclear factor NF-kappa-B p105 subunit;
DE   AltName: Full=DNA-binding factor KBF1;
DE   AltName: Full=EBP-1;
DE   AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1;
DE   Contains:
DE     RecName: Full=Nuclear factor NF-kappa-B p50 subunit;
GN   Name=NFKB1;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0001071; F:nucleic acid binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000975; F:regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IDA:MGI.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:MGI.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0032269; P:negative regulation of cellular protein metabolic process; IC:BHF-UCL.
DR   GO; GO:0032375; P:negative regulation of cholesterol transport; IC:BHF-UCL.
DR   GO; GO:0001818; P:negative regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0045083; P:negative regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0010957; P:negative regulation of vitamin D biosynthetic process; IC:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IC:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   NFKB2_HUMAN             Reviewed;         900 AA.
AC   Q00653; A8K9D9; D3DR83; Q04860; Q9BU75; Q9H471; Q9H472;
DE   RecName: Full=Nuclear factor NF-kappa-B p100 subunit;
DE   AltName: Full=DNA-binding factor KBF2;
DE   AltName: Full=H2TF1;
DE   AltName: Full=Lymphocyte translocation chromosome 10 protein;
DE   AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2;
DE   AltName: Full=Oncogene Lyt-10;
DE            Short=Lyt10;
DE   Contains:
DE     RecName: Full=Nuclear factor NF-kappa-B p52 subunit;
GN   Name=NFKB2; Synonyms=LYT10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0002268; P:follicular dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0002467; P:germinal center formation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   NFL_HUMAN               Reviewed;         543 AA.
AC   P07196; B9ZVN2; Q16154; Q8IU72;
DE   RecName: Full=Neurofilament light polypeptide;
DE            Short=NF-L;
DE   AltName: Full=68 kDa neurofilament protein;
DE   AltName: Full=Neurofilament triplet L protein;
GN   Name=NEFL; Synonyms=NF68, NFL;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; ISS:BHF-UCL.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IDA:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; IMP:UniProtKB.
DR   GO; GO:0019896; P:axon transport of mitochondrion; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0045109; P:intermediate filament organization; IMP:UniProtKB.
DR   GO; GO:0033693; P:neurofilament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0008090; P:retrograde axon cargo transport; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   NFM_HUMAN               Reviewed;         916 AA.
AC   P07197; B4DGN2; E9PBF7; Q4QRK6;
DE   RecName: Full=Neurofilament medium polypeptide;
DE            Short=NF-M;
DE   AltName: Full=160 kDa neurofilament protein;
DE   AltName: Full=Neurofilament 3;
DE   AltName: Full=Neurofilament triplet M protein;
GN   Name=NEFM; Synonyms=NEF3, NFM;
DR   GO; GO:0008017; F:microtubule binding; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0033693; P:neurofilament bundle assembly; TAS:BHF-UCL.
DR   GO; GO:0031133; P:regulation of axon diameter; IEA:Ensembl.
//
ID   NFRKB_HUMAN             Reviewed;        1299 AA.
AC   Q6P4R8; Q12869; Q15312; Q9H048;
DE   RecName: Full=Nuclear factor related to kappa-B-binding protein;
DE   AltName: Full=DNA-binding protein R kappa-B;
DE   AltName: Full=INO80 complex subunit G;
GN   Name=NFRKB; Synonyms=INO80G;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFS1_HUMAN              Reviewed;         457 AA.
AC   Q9Y697; B3KMA5; B4DXK9; E1P5R8; F5GYK5; Q6P0L8; Q9NTZ5; Q9Y481;
DE   RecName: Full=Cysteine desulfurase, mitochondrial;
DE            EC=2.8.1.7;
DE   Flags: Precursor;
GN   Name=NFS1; Synonyms=NIFS; ORFNames=HUSSY-08;
DR   GO; GO:0031071; F:cysteine desulfurase activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006534; P:cysteine metabolic process; IEA:InterPro.
DR   GO; GO:0018283; P:iron incorporation into metallo-sulfur cluster; IDA:HGNC.
DR   GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0032324; P:molybdopterin cofactor biosynthetic process; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NFU1_HUMAN              Reviewed;         254 AA.
AC   Q9UMS0; B4DUL9; Q53QE5; Q6VNZ8; Q7Z5B1; Q7Z5B2; Q9Y322;
DE   RecName: Full=NFU1 iron-sulfur cluster scaffold homolog, mitochondrial;
DE   AltName: Full=HIRA-interacting protein 5;
DE   Flags: Precursor;
GN   Name=NFU1; Synonyms=HIRIP5; ORFNames=CGI-33;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IDA:UniProtKB.
//
ID   NFX1_HUMAN              Reviewed;        1120 AA.
AC   Q12986; A8K6H8; Q5VXW6; Q96EL5; Q9BXI1;
DE   RecName: Full=Transcriptional repressor NF-X1;
DE            EC=6.3.2.-;
DE   AltName: Full=Nuclear transcription factor, X box-binding protein 1;
GN   Name=NFX1; Synonyms=NFX2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045347; P:negative regulation of MHC class II biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NFXL1_HUMAN             Reviewed;         911 AA.
AC   Q6ZNB6; B1Q2K1; Q86VG1; Q8WVH1;
DE   RecName: Full=NF-X1-type zinc finger protein NFXL1;
DE   AltName: Full=Ovarian zinc finger protein;
DE            Short=hOZFP;
GN   Name=NFXL1; Synonyms=OZFP;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   NFYA_HUMAN              Reviewed;         347 AA.
AC   P23511; Q8IXU0;
DE   RecName: Full=Nuclear transcription factor Y subunit alpha;
DE   AltName: Full=CAAT box DNA-binding protein subunit A;
DE   AltName: Full=Nuclear transcription factor Y subunit A;
DE            Short=NF-YA;
GN   Name=NFYA;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NFYB_HUMAN              Reviewed;         207 AA.
AC   P25208; A8K7B9; Q96IY8;
DE   RecName: Full=Nuclear transcription factor Y subunit beta;
DE   AltName: Full=CAAT box DNA-binding protein subunit B;
DE   AltName: Full=Nuclear transcription factor Y subunit B;
DE            Short=NF-YB;
GN   Name=NFYB; Synonyms=HAP3;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NFYC_HUMAN              Reviewed;         458 AA.
AC   Q13952; B4DUS6; B4DW63; D3DPV9; F8VWM3; Q59GY4; Q5T6K8; Q5T6K9;
AC   Q5T6L1; Q5TZR6; Q92869; Q9HBX1; Q9NXB5; Q9UM67; Q9UML0; Q9UMT7;
DE   RecName: Full=Nuclear transcription factor Y subunit gamma;
DE   AltName: Full=CAAT box DNA-binding protein subunit C;
DE   AltName: Full=Nuclear transcription factor Y subunit C;
DE            Short=NF-YC;
DE   AltName: Full=Transactivator HSM-1/2;
GN   Name=NFYC;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NGAL_HUMAN              Reviewed;         198 AA.
AC   P80188; A6NII8; B4DWV4; B7ZAA2; P30150; Q5SYV9; Q5SYW0; Q6FGL5;
AC   Q92683;
DE   RecName: Full=Neutrophil gelatinase-associated lipocalin;
DE            Short=NGAL;
DE   AltName: Full=25 kDa alpha-2-microglobulin-related subunit of MMP-9;
DE   AltName: Full=Lipocalin-2;
DE   AltName: Full=Oncogene 24p3;
DE   AltName: Full=Siderocalin LCN2;
DE   AltName: Full=p25;
DE   Flags: Precursor;
GN   Name=LCN2; Synonyms=HNL, NGAL;
DR   GO; GO:0005506; F:iron ion binding; ISS:UniProtKB.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0031669; P:cellular response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0031346; P:positive regulation of cell projection organization; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEA:Ensembl.
DR   GO; GO:0015891; P:siderophore transport; ISS:UniProtKB.
//
ID   NGAP_HUMAN              Reviewed;        1139 AA.
AC   Q9UJF2; F8W755; O95174; Q2TB22; Q5TFU9;
DE   RecName: Full=Ras GTPase-activating protein nGAP;
DE   AltName: Full=RAS protein activator-like 2;
GN   Name=RASAL2; Synonyms=NGAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NGBR_HUMAN              Reviewed;         293 AA.
AC   Q96E22; B2RWQ4; O00251;
DE   RecName: Full=Nogo-B receptor;
DE            Short=NgBR;
DE   AltName: Full=Nuclear undecaprenyl pyrophosphate synthase 1 homolog;
DE   Flags: Precursor;
GN   Name=NUS1; Synonyms=C6orf68, NGBR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0032367; P:intracellular cholesterol transport; IGI:MGI.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055092; P:sterol homeostasis; IEA:Ensembl.
//
ID   NGB_HUMAN               Reviewed;         151 AA.
AC   Q9NPG2;
DE   RecName: Full=Neuroglobin;
GN   Name=NGB;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen transporter activity; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0015671; P:oxygen transport; NAS:UniProtKB.
//
ID   NGEF_HUMAN              Reviewed;         710 AA.
AC   Q8N5V2; B4DMB8; B9A045; E9PC42; Q53QQ4; Q53ST7; Q6GMQ5; Q9NQD6;
DE   RecName: Full=Ephexin-1;
DE   AltName: Full=Eph-interacting exchange protein;
DE   AltName: Full=Neuronal guanine nucleotide exchange factor;
GN   Name=NGEF;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   NGDN_HUMAN              Reviewed;         315 AA.
AC   Q8NEJ9; A8K760; Q9Y400;
DE   RecName: Full=Neuroguidin;
DE   AltName: Full=Centromere accumulated nuclear protein 1;
DE            Short=CANu1;
DE   AltName: Full=EIF4E-binding protein;
GN   Name=NGDN; Synonyms=C14orf120;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   NGF_HUMAN               Reviewed;         241 AA.
AC   P01138; A1A4E5; Q6FHA0; Q96P60; Q9P2Q8; Q9UKL8;
DE   RecName: Full=Beta-nerve growth factor;
DE            Short=Beta-NGF;
DE   Flags: Precursor;
GN   Name=NGF; Synonyms=NGFB;
DR   GO; GO:0005163; F:nerve growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:2000675; P:negative regulation of type B pancreatic cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0032455; P:nerve growth factor processing; TAS:Reactome.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IDA:MGI.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051388; P:positive regulation of neurotrophin TRK receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0010193; P:response to ozone; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:Reactome.
//
ID   NGLY1_HUMAN             Reviewed;         654 AA.
AC   Q96IV0; B4DJE9; Q59FB1; Q6PJD8; Q9BVR8; Q9NR70;
DE   RecName: Full=Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase;
DE            Short=PNGase;
DE            Short=hPNGase;
DE            EC=3.5.1.52;
DE   AltName: Full=N-glycanase 1;
DE   AltName: Full=Peptide:N-glycanase;
GN   Name=NGLY1; Synonyms=PNG1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000224; F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IDA:UniProtKB.
//
ID   NGN1_HUMAN              Reviewed;         237 AA.
AC   Q92886; Q5U0Q9; Q96HE1;
DE   RecName: Full=Neurogenin-1;
DE            Short=NGN-1;
DE   AltName: Full=Class A basic helix-loop-helix protein 6;
DE            Short=bHLHa6;
DE   AltName: Full=Neurogenic basic-helix-loop-helix protein;
DE   AltName: Full=Neurogenic differentiation factor 3;
DE            Short=NeuroD3;
GN   Name=NEUROG1; Synonyms=BHLHA6, NEUROD3, NGN, NGN1;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0031536; P:positive regulation of exit from mitosis; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NGN2_HUMAN              Reviewed;         272 AA.
AC   Q9H2A3; Q8N416;
DE   RecName: Full=Neurogenin-2;
DE            Short=NGN-2;
DE   AltName: Full=Class A basic helix-loop-helix protein 8;
DE            Short=bHLHa8;
DE   AltName: Full=Protein atonal homolog 4;
GN   Name=NEUROG2; Synonyms=ATOH4, BHLHA8, NGN2;
DR   GO; GO:0070888; F:E-box binding; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NGN3_HUMAN              Reviewed;         214 AA.
AC   Q9Y4Z2; Q5VVI0; Q6DJX6; Q9BY24;
DE   RecName: Full=Neurogenin-3;
DE            Short=NGN-3;
DE   AltName: Full=Class A basic helix-loop-helix protein 7;
DE            Short=bHLHa7;
DE   AltName: Full=Protein atonal homolog 5;
GN   Name=NEUROG3; Synonyms=ATOH5, BHLHA7, NGN3;
DR   GO; GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0060290; P:transdifferentiation; ISS:UniProtKB.
//
ID   NGRNL_HUMAN             Reviewed;         184 AA.
AC   A8MWC7;
DE   RecName: Full=Putative neugrin-like protein;
//
ID   NGRN_HUMAN              Reviewed;         291 AA.
AC   Q9NPE2; B2R6M8; Q4V9L7; Q9HBL4;
DE   RecName: Full=Neugrin;
DE   AltName: Full=Mesenchymal stem cell protein DSC92;
DE   AltName: Full=Neurite outgrowth-associated protein;
DE   AltName: Full=Spinal cord-derived protein FI58G;
DE   Flags: Precursor;
GN   Name=NGRN; Synonyms=FI58G; ORFNames=HT020;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; NAS:UniProtKB.
//
ID   NH2L1_HUMAN             Reviewed;         128 AA.
AC   P55769;
DE   RecName: Full=NHP2-like protein 1;
DE   AltName: Full=High mobility group-like nuclear protein 2 homolog 1;
DE   AltName: Full=OTK27;
DE   AltName: Full=SNU13 homolog;
DE            Short=hSNU13;
DE   AltName: Full=U4/U6.U5 tri-snRNP 15.5 kDa protein;
DE   Contains:
DE     RecName: Full=NHP2-like protein 1, N-terminally processed;
GN   Name=NHP2L1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   NHEJ1_HUMAN             Reviewed;         299 AA.
AC   Q9H9Q4; B8ZZA4; Q4ZFW7; Q6IA64; Q96JS9;
DE   RecName: Full=Non-homologous end-joining factor 1;
DE   AltName: Full=Protein cernunnos;
DE   AltName: Full=XRCC4-like factor;
GN   Name=NHEJ1; Synonyms=XLF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IMP:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.
DR   GO; GO:0051351; P:positive regulation of ligase activity; NAS:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; IMP:UniProtKB.
//
ID   NHLC1_HUMAN             Reviewed;         395 AA.
AC   Q6VVB1; Q3SYB1; Q5VUK7; Q6IMH1;
DE   RecName: Full=E3 ubiquitin-protein ligase NHLRC1;
DE            EC=6.3.2.-;
DE   AltName: Full=Malin;
DE   AltName: Full=NHL repeat-containing protein 1;
GN   Name=NHLRC1; Synonyms=EPM2B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NHLC3_HUMAN             Reviewed;         347 AA.
AC   Q5JS37; B2RTZ2; B4DTL0; Q69YI9;
DE   RecName: Full=NHL repeat-containing protein 3;
DE   Flags: Precursor;
GN   Name=NHLRC3;
//
ID   NHLC4_HUMAN             Reviewed;         123 AA.
AC   P0CG21; B8ZZ27; Q8N233; Q96AX3; Q96S23;
DE   RecName: Full=NHL-repeat-containing protein 4;
GN   Name=NHLRC4;
//
ID   NHLC2_HUMAN             Reviewed;         726 AA.
AC   Q8NBF2; Q8N1H1; Q8N5A6;
DE   RecName: Full=NHL repeat-containing protein 2;
GN   Name=NHLRC2;
//
ID   NHP2_HUMAN              Reviewed;         153 AA.
AC   Q9NX24; A6NKY8; Q9P095;
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit 2;
DE   AltName: Full=Nucleolar protein family A member 2;
DE   AltName: Full=snoRNP protein NHP2;
GN   Name=NHP2; Synonyms=NOLA2; ORFNames=HSPC286;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0031118; P:rRNA pseudouridine synthesis; ISS:UniProtKB.
//
ID   NHRF1_HUMAN             Reviewed;         358 AA.
AC   O14745; O43552; Q86WQ5;
DE   RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF1;
DE            Short=NHERF-1;
DE   AltName: Full=Ezrin-radixin-moesin-binding phosphoprotein 50;
DE            Short=EBP50;
DE   AltName: Full=Regulatory cofactor of Na(+)/H(+) exchanger;
DE   AltName: Full=Sodium-hydrogen exchanger regulatory factor 1;
DE   AltName: Full=Solute carrier family 9 isoform A3 regulatory factor 1;
GN   Name=SLC9A3R1; Synonyms=NHERF, NHERF1;
DR   GO; GO:0031698; F:beta-2 adrenergic receptor binding; IPI:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0017081; F:chloride channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0070851; F:growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032782; P:bile acid secretion; ISS:UniProtKB.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IEA:Ensembl.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0034635; P:glutathione transport; ISS:UniProtKB.
DR   GO; GO:0030033; P:microvillus assembly; IMP:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0010766; P:negative regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0032416; P:negative regulation of sodium:proton antiporter activity; IEA:Ensembl.
DR   GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0044062; P:regulation of excretion; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0032415; P:regulation of sodium:proton antiporter activity; NAS:UniProtKB.
DR   GO; GO:0070293; P:renal absorption; ISS:UniProtKB.
DR   GO; GO:0097291; P:renal phosphate ion absorption; IMP:UniProtKB.
DR   GO; GO:0003096; P:renal sodium ion transport; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NHRF2_HUMAN             Reviewed;         337 AA.
AC   Q15599; D3DU84; D3DU85; H3BSV6; O00272; O00556; Q3KQY7;
DE   RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2;
DE            Short=NHERF-2;
DE   AltName: Full=NHE3 kinase A regulatory protein E3KARP;
DE   AltName: Full=SRY-interacting protein 1;
DE            Short=SIP-1;
DE   AltName: Full=Sodium-hydrogen exchanger regulatory factor 2;
DE   AltName: Full=Solute carrier family 9 isoform A3 regulatory factor 2;
DE   AltName: Full=Tyrosine kinase activator protein 1;
DE            Short=TKA-1;
GN   Name=SLC9A3R2; Synonyms=NHERF2;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   NHRF3_HUMAN             Reviewed;         519 AA.
AC   Q5T2W1; B4DPB9; E7EU02; O60450; Q5T5P6; Q9BQ41;
DE   RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF3;
DE            Short=NHERF-3;
DE   AltName: Full=CFTR-associated protein of 70 kDa;
DE   AltName: Full=Na(+)/H(+) exchanger regulatory factor 3;
DE   AltName: Full=Na/Pi cotransporter C-terminal-associated protein 1;
DE            Short=NaPi-Cap1;
DE   AltName: Full=PDZ domain-containing protein 1;
DE   AltName: Full=Sodium-hydrogen exchanger regulatory factor 3;
GN   Name=PDZK1; Synonyms=CAP70, NHERF3, PDZD1;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:UniProtKB.
DR   GO; GO:0015879; P:carnitine transport; IDA:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0015893; P:drug transport; NAS:UniProtKB.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0034767; P:positive regulation of ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0044070; P:regulation of anion transport; ISS:UniProtKB.
DR   GO; GO:0006810; P:transport; IDA:BHF-UCL.
//
ID   NHRF4_HUMAN             Reviewed;         571 AA.
AC   Q86UT5; Q8N6R4; Q8NAW7; Q8NEX7; Q9H5Z3;
DE   RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF4;
DE            Short=NHERF-4;
DE   AltName: Full=Intestinal and kidney-enriched PDZ protein;
DE   AltName: Full=Natrium-phosphate cotransporter IIa C-terminal-associated protein 2;
DE            Short=Na/Pi cotransporter C-terminal-associated protein 2;
DE            Short=NaPi-Cap2;
DE   AltName: Full=PDZ domain-containing protein 2;
DE   AltName: Full=PDZ domain-containing protein 3;
DE   AltName: Full=Sodium-hydrogen exchanger regulatory factor 4;
GN   Name=PDZD3; Synonyms=IKEPP, NHERF4, PDZK2; ORFNames=DLNB27;
DR   GO; GO:0030251; F:guanylate cyclase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0008200; F:ion channel inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019934; P:cGMP-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; NAS:UniProtKB.
DR   GO; GO:0030827; P:negative regulation of cGMP biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0031283; P:negative regulation of guanylate cyclase activity; IDA:GOC.
DR   GO; GO:0007168; P:receptor guanylyl cyclase signaling pathway; IC:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; TAS:UniProtKB.
DR   GO; GO:0006833; P:water transport; NAS:UniProtKB.
//
ID   NHSL1_HUMAN             Reviewed;        1610 AA.
AC   Q5SYE7; Q3ZCS5; Q5SYE8; Q9P2J0;
DE   RecName: Full=NHS-like protein 1;
GN   Name=NHSL1; Synonyms=C6orf63, KIAA1357;
//
ID   NHSL2_HUMAN             Reviewed;         709 AA.
AC   Q5HYW2; B2RN94;
DE   RecName: Full=NHS-like protein 2;
GN   Name=NHSL2;
//
ID   NHS_HUMAN               Reviewed;        1651 AA.
AC   Q6T4R5; B7ZVX8; E2DH69; Q5J7Q0; Q5J7Q1; Q68DR5;
DE   RecName: Full=Nance-Horan syndrome protein;
DE   AltName: Full=Congenital cataracts and dental anomalies protein;
GN   Name=NHS;
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
//
ID   NIBAN_HUMAN             Reviewed;         928 AA.
AC   Q9BZQ8; Q2TTR2; Q5TEM8; Q8TEI5; Q9H593; Q9H9Y8; Q9HCB9;
DE   RecName: Full=Protein Niban;
DE   AltName: Full=Cell growth-inhibiting gene 39 protein;
DE   AltName: Full=Protein FAM129A;
GN   Name=FAM129A; Synonyms=C1orf24, NIBAN; ORFNames=GIG39;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; ISS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
//
ID   NIBL1_HUMAN             Reviewed;         746 AA.
AC   Q96TA1; Q4LE55; Q5VVW6; Q5VVW7; Q9BUS2; Q9NT35;
DE   RecName: Full=Niban-like protein 1;
DE   AltName: Full=Meg-3;
DE   AltName: Full=Melanoma invasion by ERK;
DE            Short=MINERVA;
DE   AltName: Full=Protein FAM129B;
GN   Name=FAM129B; Synonyms=C9orf88;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
//
ID   NIBL2_HUMAN             Reviewed;         697 AA.
AC   Q86XR2; B4DNU3; B4DVN7; Q7Z6H6; Q86XR3; Q86XR4; Q8TEQ3;
DE   RecName: Full=Niban-like protein 2;
DE   AltName: Full=B-cell novel protein 1;
DE   AltName: Full=Protein FAM129C;
GN   Name=FAM129C; Synonyms=BCNP1;
//
ID   NICA_HUMAN              Reviewed;         709 AA.
AC   Q92542; Q5T207; Q5T208; Q86VV5;
DE   RecName: Full=Nicastrin;
DE   Flags: Precursor;
GN   Name=NCSTN; Synonyms=KIAA0253; ORFNames=UNQ1874/PRO4317;
DR   GO; GO:0004175; F:endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; TAS:HGNC.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IEA:Ensembl.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0002262; P:myeloid cell homeostasis; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:HGNC.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; ISS:UniProtKB.
DR   GO; GO:0016485; P:protein processing; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
//
ID   NICN1_HUMAN             Reviewed;         213 AA.
AC   Q9BSH3; Q8IZQ2;
DE   RecName: Full=Nicolin-1;
DE   AltName: Full=NPCEDRG;
DE   AltName: Full=Tubulin polyglutamylase complex subunit 5;
DE            Short=PGs5;
GN   Name=NICN1;
//
ID   NID1_HUMAN              Reviewed;        1247 AA.
AC   P14543; Q14942; Q59FL2; Q5TAF2; Q5TAF3; Q86XD7;
DE   RecName: Full=Nidogen-1;
DE            Short=NID-1;
DE   AltName: Full=Entactin;
DE   Flags: Precursor;
GN   Name=NID1; Synonyms=NID;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005518; F:collagen binding; IDA:BHF-UCL.
DR   GO; GO:0043236; F:laminin binding; IDA:BHF-UCL.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:BHF-UCL.
DR   GO; GO:0071711; P:basement membrane organization; TAS:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0032836; P:glomerular basement membrane development; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   NID2_HUMAN              Reviewed;        1375 AA.
AC   Q14112; A8K6I7; B4DU19; O43710;
DE   RecName: Full=Nidogen-2;
DE            Short=NID-2;
DE   AltName: Full=Osteonidogen;
DE   Flags: Precursor;
GN   Name=NID2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005518; F:collagen binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071711; P:basement membrane organization; TAS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   NIM1_HUMAN              Reviewed;         436 AA.
AC   Q8IY84; B3KVM1;
DE   RecName: Full=Serine/threonine-protein kinase NIM1;
DE            EC=2.7.11.1;
DE   AltName: Full=NIM1 serine/threonine-protein kinase;
GN   Name=NIM1K; Synonyms=NIM1;
DR   GuidetoPHARMACOLOGY; 2291; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   NINJ1_HUMAN             Reviewed;         152 AA.
AC   Q92982; Q6GU89; Q8WUV5; Q9BT07;
DE   RecName: Full=Ninjurin-1;
DE   AltName: Full=Nerve injury-induced protein 1;
GN   Name=NINJ1;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0042246; P:tissue regeneration; IEA:InterPro.
//
ID   NINJ2_HUMAN             Reviewed;         142 AA.
AC   Q9NZG7;
DE   RecName: Full=Ninjurin-2;
DE   AltName: Full=Nerve injury-induced protein 2;
GN   Name=NINJ2;
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:ProtInc.
DR   GO; GO:0042246; P:tissue regeneration; IEA:InterPro.
//
ID   NINL_HUMAN              Reviewed;        1382 AA.
AC   Q9Y2I6; A6NJN0; B3V9H6; B7Z1V8; Q5JYP0; Q8NE38; Q9NQE3;
DE   RecName: Full=Ninein-like protein;
GN   Name=NINL; Synonyms=KIAA0980, NLP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   NIN_HUMAN               Reviewed;        2090 AA.
AC   Q8N4C6; A6NDB8; B7WPA3; C9JSB6; C9JSG2; C9JXL2; Q5BKU3; Q6P0P6;
AC   Q9BWU6; Q9C012; Q9C013; Q9C014; Q9H5I6; Q9HAT7; Q9HBY5; Q9HCK7;
AC   Q9UH61;
DE   RecName: Full=Ninein;
DE            Short=hNinein;
DE   AltName: Full=Glycogen synthase kinase 3 beta-interacting protein;
DE            Short=GSK3B-interacting protein;
GN   Name=NIN; Synonyms=KIAA1565;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051642; P:centrosome localization; TAS:HGNC.
DR   GO; GO:0090222; P:centrosome-templated microtubule nucleation; IEA:Ensembl.
DR   GO; GO:0034454; P:microtubule anchoring at centrosome; IEA:Ensembl.
//
ID   NIP7_HUMAN              Reviewed;         180 AA.
AC   Q9Y221; B2RD04; Q9NZZ0;
DE   RecName: Full=60S ribosome subunit biogenesis protein NIP7 homolog;
DE   AltName: Full=KD93;
GN   Name=NIP7;
GN   ORFNames=CGI-37, HSPC031, HSPC180, OK/SW-cl.76, OK/SW-cl.78;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042255; P:ribosome assembly; IEA:InterPro.
//
ID   NIPA1_HUMAN             Reviewed;         329 AA.
AC   Q7RTP0; B2RA76; Q5HYA9; Q7KZB0; Q86XW4;
DE   RecName: Full=Magnesium transporter NIPA1;
DE   AltName: Full=Non-imprinted in Prader-Willi/Angelman syndrome region protein 1;
DE   AltName: Full=Spastic paraplegia 6 protein;
GN   Name=NIPA1; Synonyms=SPG6;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   NIPA2_HUMAN             Reviewed;         360 AA.
AC   Q8N8Q9; F8W7Y8; Q96F03; Q9BVS2;
DE   RecName: Full=Magnesium transporter NIPA2;
DE   AltName: Full=Non-imprinted in Prader-Willi/Angelman syndrome region protein 2;
GN   Name=NIPA2;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
//
ID   NIPA3_HUMAN             Reviewed;         410 AA.
AC   Q6NVV3; B3KTB0; Q68DA9;
DE   RecName: Full=Magnesium transporter NIPA3;
DE   AltName: Full=NIPA-like protein 1;
DE   AltName: Full=Non-imprinted in Prader-Willi/Angelman syndrome region protein 3;
GN   Name=NIPAL1; Synonyms=NIPA3, NPAL1;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
//
ID   NIPA4_HUMAN             Reviewed;         466 AA.
AC   Q0D2K0; A8S6F1; A8S6F5; A8S6F8; B4DLF3; Q0D2J8; Q0D2J9;
DE   RecName: Full=Magnesium transporter NIPA4;
DE   AltName: Full=Ichthyin;
DE   AltName: Full=NIPA-like protein 4;
DE   AltName: Full=Non-imprinted in Prader-Willi/Angelman syndrome region protein 4;
GN   Name=NIPAL4; Synonyms=ICHN, NIPA4;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
//
ID   NIPA_HUMAN              Reviewed;         502 AA.
AC   Q86WB0; A6NH66; Q75MF3; Q75MF4; Q8N330; Q96F75; Q9HA34; Q9NVX4;
AC   Q9P0R0;
DE   RecName: Full=Nuclear-interacting partner of ALK;
DE   AltName: Full=Nuclear-interacting partner of anaplastic lymphoma kinase;
DE            Short=hNIPA;
DE   AltName: Full=Zinc finger C3HC-type protein 1;
GN   Name=ZC3HC1; Synonyms=NIPA; ORFNames=HSPC216;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   NIPBL_HUMAN             Reviewed;        2804 AA.
AC   Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4;
DE   RecName: Full=Nipped-B-like protein;
DE   AltName: Full=Delangin;
DE   AltName: Full=SCC2 homolog;
GN   Name=NIPBL; Synonyms=IDN3;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:BHF-UCL.
DR   GO; GO:0034613; P:cellular protein localization; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071481; P:cellular response to X-ray; IMP:UniProtKB.
DR   GO; GO:0050890; P:cognition; IMP:BHF-UCL.
DR   GO; GO:0048589; P:developmental growth; IMP:BHF-UCL.
DR   GO; GO:0042471; P:ear morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0035261; P:external genitalia morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0048592; P:eye morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060325; P:face morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0035136; P:forelimb morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0061010; P:gall bladder development; IMP:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; NAS:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IDA:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0048638; P:regulation of developmental growth; IMP:BHF-UCL.
DR   GO; GO:0045995; P:regulation of embryonic development; IMP:BHF-UCL.
DR   GO; GO:0042634; P:regulation of hair cycle; IMP:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0061038; P:uterus morphogenesis; IMP:BHF-UCL.
//
ID   NIPS1_HUMAN             Reviewed;         284 AA.
AC   Q9BPW8; B2RAY3; O43800;
DE   RecName: Full=Protein NipSnap homolog 1;
DE            Short=NipSnap1;
GN   Name=NIPSNAP1;
DR   GO; GO:0042165; F:neurotransmitter binding; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
//
ID   NIPS2_HUMAN             Reviewed;         286 AA.
AC   O75323; C9IYJ3; O43801; Q53X96;
DE   RecName: Full=Protein NipSnap homolog 2;
DE            Short=NipSnap2;
DE   AltName: Full=Glioblastoma-amplified sequence;
GN   Name=GBAS; Synonyms=NIPSNAP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:2000984; P:negative regulation of ATP citrate synthase activity; IMP:BHF-UCL.
DR   GO; GO:0006119; P:oxidative phosphorylation; IMP:BHF-UCL.
//
ID   NISCH_HUMAN             Reviewed;        1504 AA.
AC   Q9Y2I1; C9J245; Q6PGP3; Q6PIB4; Q7L8M3; Q7Z2X6; Q9UES6; Q9UEU4;
AC   Q9UFW3;
DE   RecName: Full=Nischarin;
DE   AltName: Full=Imidazoline receptor 1;
DE            Short=I-1;
DE            Short=IR1;
DE   AltName: Full=Imidazoline receptor antisera-selected protein;
DE            Short=hIRAS;
DE   AltName: Full=Imidazoline-1 receptor;
DE            Short=I1R;
DE   AltName: Full=Imidazoline-1 receptor candidate protein;
DE            Short=I-1 receptor candidate protein;
DE            Short=I1R candidate protein;
GN   Name=NISCH; Synonyms=IRAS, KIAA0975;
DR   GO; GO:0008227; F:G-protein coupled amine receptor activity; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0048243; P:norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0016601; P:Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
//
ID   NIT1_HUMAN              Reviewed;         327 AA.
AC   Q86X76; B1AQP3; D3DVF4; O76091;
DE   RecName: Full=Nitrilase homolog 1;
DE            EC=3.5.-.-;
GN   Name=NIT1;
DR   GO; GO:0000257; F:nitrilase activity; TAS:ProtInc.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
//
ID   NIT2_HUMAN              Reviewed;         276 AA.
AC   Q9NQR4; B2R9A3; D3DN47; Q8WUF0;
DE   RecName: Full=Omega-amidase NIT2;
DE            EC=3.5.1.3;
DE   AltName: Full=Nitrilase homolog 2;
GN   Name=NIT2; ORFNames=CUA002;
DR   GO; GO:0050152; F:omega-amidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
//
ID   NJMU_HUMAN              Reviewed;         396 AA.
AC   Q9HAS0; Q7Z2H4;
DE   RecName: Full=Protein Njmu-R1;
GN   Name=C17orf75;
//
ID   NK1R_HUMAN              Reviewed;         407 AA.
AC   P25103; A8K150;
DE   RecName: Full=Substance-P receptor;
DE            Short=SPR;
DE   AltName: Full=NK-1 receptor;
DE            Short=NK-1R;
DE   AltName: Full=Tachykinin receptor 1;
GN   Name=TACR1; Synonyms=NK1R, TAC1R;
DR   GuidetoPHARMACOLOGY; 360; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016496; F:substance P receptor activity; IEA:Ensembl.
DR   GO; GO:0004995; F:tachykinin receptor activity; TAS:ProtInc.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0002118; P:aggressive behavior; IEA:Ensembl.
DR   GO; GO:0003051; P:angiotensin-mediated drinking behavior; IEA:Ensembl.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0009582; P:detection of abiotic stimulus; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0035106; P:operant conditioning; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045760; P:positive regulation of action potential; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0050671; P:positive regulation of lymphocyte proliferation; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0046878; P:positive regulation of saliva secretion; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0014910; P:regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0048660; P:regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0010996; P:response to auditory stimulus; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0010193; P:response to ozone; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0060083; P:smooth muscle contraction involved in micturition; IEA:Ensembl.
DR   GO; GO:0042713; P:sperm ejaculation; IEA:Ensembl.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; IDA:BHF-UCL.
//
ID   NK2R_HUMAN              Reviewed;         398 AA.
AC   P21452; A8K7I1; Q4QRI5; Q8NGQ8; Q9UDE6; Q9UDE7;
DE   RecName: Full=Substance-K receptor;
DE            Short=SKR;
DE   AltName: Full=NK-2 receptor;
DE            Short=NK-2R;
DE   AltName: Full=Neurokinin A receptor;
DE   AltName: Full=Tachykinin receptor 2;
GN   Name=TACR2; Synonyms=NK2R, NKNAR, TAC2R;
DR   GuidetoPHARMACOLOGY; 361; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016497; F:substance K receptor activity; IEA:Ensembl.
DR   GO; GO:0004995; F:tachykinin receptor activity; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0014827; P:intestine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0033685; P:negative regulation of luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0035106; P:operant conditioning; IEA:Ensembl.
DR   GO; GO:0014057; P:positive regulation of acetylcholine secretion, neurotransmission; IEA:Ensembl.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0070459; P:prolactin secretion; IEA:Ensembl.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; TAS:ProtInc.
//
ID   NK3R_HUMAN              Reviewed;         465 AA.
AC   P29371; Q0P510;
DE   RecName: Full=Neuromedin-K receptor;
DE            Short=NKR;
DE   AltName: Full=NK-3 receptor;
DE            Short=NK-3R;
DE   AltName: Full=Neurokinin B receptor;
DE   AltName: Full=Tachykinin receptor 3;
GN   Name=TACR3; Synonyms=NK3R, TAC3R;
DR   GuidetoPHARMACOLOGY; 362; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004995; F:tachykinin receptor activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0042538; P:hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0060259; P:regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; TAS:ProtInc.
//
ID   NKAI1_HUMAN             Reviewed;         207 AA.
AC   Q4KMZ8; A2VDJ3; B7Z5W9; Q9H9M7;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1;
DE            Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1;
DE   AltName: Full=Protein FAM77C;
DE   Flags: Precursor;
GN   Name=NKAIN1; Synonyms=FAM77C;
//
ID   NKAI3_HUMAN             Reviewed;         197 AA.
AC   Q8N8D7;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3;
DE            Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3;
DE   AltName: Full=Protein FAM77D;
GN   Name=NKAIN3; Synonyms=FAM77D;
//
ID   NKAI2_HUMAN             Reviewed;         208 AA.
AC   Q5VXU1; Q8IYR4; Q8TF67;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2;
DE            Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2;
DE   AltName: Full=Protein FAM77B;
DE   AltName: Full=T-cell lymphoma breakpoint-associated target protein 1;
GN   Name=NKAIN2; Synonyms=FAM77B, TCBA1;
//
ID   NKAI4_HUMAN             Reviewed;         208 AA.
AC   Q8IVV8; Q4VXQ6; Q9BQU8; Q9BQU9;
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4;
DE            Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4;
DE   AltName: Full=Protein FAM77A;
GN   Name=NKAIN4; Synonyms=C20orf58, FAM77A;
//
ID   NKAPL_HUMAN             Reviewed;         402 AA.
AC   Q5M9Q1; Q3MIV1; Q9H4Q7;
DE   RecName: Full=NKAP-like protein;
GN   Name=NKAPL; Synonyms=C6orf194;
//
ID   NKAP_HUMAN              Reviewed;         415 AA.
AC   Q8N5F7; Q6IPW6; Q96BQ2; Q9H638;
DE   RecName: Full=NF-kappa-B-activating protein;
GN   Name=NKAP;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030851; P:granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IMP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NKD1_HUMAN              Reviewed;         470 AA.
AC   Q969G9; B2RC39; Q8WZ08;
DE   RecName: Full=Protein naked cuticle homolog 1;
DE            Short=Naked-1;
DE            Short=hNkd;
DE            Short=hNkd1;
GN   Name=NKD1; Synonyms=NKD; ORFNames=PP7246;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001754; P:eye photoreceptor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:1901233; P:negative regulation of convergent extension involved in axis elongation; ISS:BHF-UCL.
DR   GO; GO:1901231; P:positive regulation of non-canonical Wnt signaling pathway via JNK cascade; ISS:BHF-UCL.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:2000096; P:positive regulation of Wnt signaling pathway, planar cell polarity pathway; ISS:BHF-UCL.
DR   GO; GO:0090249; P:regulation of cell motility involved in somitogenic axis elongation; ISS:BHF-UCL.
DR   GO; GO:0007525; P:somatic muscle development; ISS:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NKD2_HUMAN              Reviewed;         451 AA.
AC   Q969F2; Q96EK8; Q9BSN0;
DE   RecName: Full=Protein naked cuticle homolog 2;
DE            Short=Naked-2;
DE            Short=hNkd2;
GN   Name=NKD2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0048210; P:Golgi vesicle fusion to target membrane; IMP:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0010954; P:positive regulation of protein processing; IDA:BHF-UCL.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NKG2A_HUMAN             Reviewed;         233 AA.
AC   P26715;
DE   RecName: Full=NKG2-A/NKG2-B type II integral membrane protein;
DE   AltName: Full=CD159 antigen-like family member A;
DE   AltName: Full=NK cell receptor A;
DE   AltName: Full=NKG2-A/B-activating NK receptor;
DE   AltName: CD_antigen=CD159a;
GN   Name=KLRC1; Synonyms=NKG2A;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   NKG2D_HUMAN             Reviewed;         216 AA.
AC   P26718; A8K7K5; A8K7P4; Q9NR41;
DE   RecName: Full=NKG2-D type II integral membrane protein;
DE   AltName: Full=Killer cell lectin-like receptor subfamily K member 1;
DE   AltName: Full=NK cell receptor D;
DE   AltName: Full=NKG2-D-activating NK receptor;
DE   AltName: CD_antigen=CD314;
GN   Name=KLRK1; Synonyms=D12S2489E, NKG2D;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0032394; F:MHC class Ib receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030101; P:natural killer cell activation; TAS:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IDA:UniProtKB.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002223; P:stimulatory C-type lectin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:BHF-UCL.
//
ID   NKG2C_HUMAN             Reviewed;         231 AA.
AC   P26717; O43802; Q52M74; Q9NR42;
DE   RecName: Full=NKG2-C type II integral membrane protein;
DE   AltName: Full=CD159 antigen-like family member C;
DE   AltName: Full=NK cell receptor C;
DE   AltName: Full=NKG2-C-activating NK receptor;
DE   AltName: CD_antigen=CD159c;
GN   Name=KLRC2; Synonyms=NKG2C;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NKG2E_HUMAN             Reviewed;         240 AA.
AC   Q07444; Q8WXA4; Q96RL0; Q9UP04;
DE   RecName: Full=NKG2-E type II integral membrane protein;
DE   AltName: Full=NK cell receptor E;
DE   AltName: Full=NKG2-E-activating NK receptor;
GN   Name=KLRC3; Synonyms=NKG2E;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   NKG2F_HUMAN             Reviewed;         158 AA.
AC   O43908; O60851;
DE   RecName: Full=NKG2-F type II integral membrane protein;
DE   AltName: Full=NK cell receptor F;
DE   AltName: Full=NKG2-F-activating NK receptor;
GN   Name=KLRC4; Synonyms=NKG2F;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   NKG7_HUMAN              Reviewed;         165 AA.
AC   Q16617;
DE   RecName: Full=Protein NKG7;
DE   AltName: Full=G-CSF-induced gene 1 protein;
DE            Short=GIG-1 protein;
DE   AltName: Full=Granule membrane protein of 17 kDa;
DE            Short=GMP-17;
DE   AltName: Full=Natural killer cell protein 7;
DE   AltName: Full=p15-TIA-1;
GN   Name=NKG7; Synonyms=GIG1;
//
ID   NKPD1_HUMAN             Reviewed;         610 AA.
AC   Q17RQ9; B7ZLG6; D6RH15; Q8N2A2;
DE   RecName: Full=NTPase KAP family P-loop domain-containing protein 1;
GN   Name=NKPD1;
//
ID   NKTR_HUMAN              Reviewed;        1462 AA.
AC   P30414;
DE   RecName: Full=NK-tumor recognition protein;
DE            Short=NK-TR protein;
DE   AltName: Full=Natural-killer cells cyclophilin-related protein;
DE   Includes:
DE     RecName: Full=Putative peptidyl-prolyl cis-trans isomerase;
DE              Short=PPIase;
DE              EC=5.2.1.8;
DE     AltName: Full=Rotamase;
GN   Name=NKTR;
DR   GO; GO:0016018; F:cyclosporin A binding; TAS:ProtInc.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   NKRF_HUMAN              Reviewed;         690 AA.
AC   O15226; G3V1N1; Q4VC41; Q9UJ91;
DE   RecName: Full=NF-kappa-B-repressing factor;
DE            Short=NFkB-repressing factor;
DE   AltName: Full=Protein ITBA4;
DE   AltName: Full=Transcription factor NRF;
GN   Name=NKRF; Synonyms=ITBA4, NRF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NKX12_HUMAN             Reviewed;         310 AA.
AC   Q9UD57;
DE   RecName: Full=NK1 transcription factor-related protein 2;
DE   AltName: Full=Homeobox protein SAX-1;
DE   AltName: Full=NKX-1.1;
GN   Name=NKX1-2; Synonyms=C10orf121, NKX1.1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   NKX11_HUMAN             Reviewed;         411 AA.
AC   Q15270;
DE   RecName: Full=NK1 transcription factor-related protein 1;
DE   AltName: Full=Homeobox protein 153;
DE            Short=HPX-153;
DE   AltName: Full=Homeobox protein SAX-2;
DE   AltName: Full=NKX-1.1;
GN   Name=NKX1-1; Synonyms=HPX153;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0050877; P:neurological system process; IEA:Ensembl.
DR   GO; GO:0043467; P:regulation of generation of precursor metabolites and energy; IEA:Ensembl.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IEA:Ensembl.
//
ID   NKX21_HUMAN             Reviewed;         371 AA.
AC   P43699; D3DSA3; O14954; O14955; Q7KZF6; Q9BRJ8;
DE   RecName: Full=Homeobox protein Nkx-2.1;
DE   AltName: Full=Homeobox protein NK-2 homolog A;
DE   AltName: Full=Thyroid nuclear factor 1;
DE   AltName: Full=Thyroid transcription factor 1;
DE            Short=TTF-1;
GN   Name=NKX2-1; Synonyms=NKX2A, TITF1, TTF1;
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0048646; P:anatomical structure formation involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0021892; P:cerebral cortex GABAergic interneuron differentiation; IEA:Ensembl.
DR   GO; GO:0060486; P:Clara cell differentiation; IEA:Ensembl.
DR   GO; GO:0031128; P:developmental induction; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEP:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEP:UniProtKB.
DR   GO; GO:0021798; P:forebrain dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0021877; P:forebrain neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0021759; P:globus pallidus development; IMP:UniProtKB.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEP:UniProtKB.
DR   GO; GO:0060430; P:lung saccule development; IEA:Ensembl.
DR   GO; GO:0042696; P:menarche; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IEP:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IMP:UniProtKB.
DR   GO; GO:0060510; P:Type II pneumocyte differentiation; IEA:Ensembl.
//
ID   NKX23_HUMAN             Reviewed;         364 AA.
AC   Q8TAU0; B4DUZ4; Q9NYS6;
DE   RecName: Full=Homeobox protein Nkx-2.3;
DE   AltName: Full=Homeobox protein NK-2 homolog C;
GN   Name=NKX2-3; Synonyms=NKX23, NKX2C;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043367; P:CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0022612; P:gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0001776; P:leukocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0002317; P:plasma cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048621; P:post-embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   NKX22_HUMAN             Reviewed;         273 AA.
AC   O95096;
DE   RecName: Full=Homeobox protein Nkx-2.2;
DE   AltName: Full=Homeobox protein NK-2 homolog B;
GN   Name=NKX2-2; Synonyms=NKX2.2, NKX2B;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0001159; F:core promoter proximal region DNA binding; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0048708; P:astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0021554; P:optic nerve development; IEA:Ensembl.
DR   GO; GO:0003326; P:pancreatic A cell fate commitment; IEA:Ensembl.
DR   GO; GO:0003329; P:pancreatic PP cell fate commitment; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021530; P:spinal cord oligodendrocyte cell fate specification; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0003323; P:type B pancreatic cell development; IEA:Ensembl.
DR   GO; GO:0003327; P:type B pancreatic cell fate commitment; IEA:Ensembl.
DR   GO; GO:0060580; P:ventral spinal cord interneuron fate determination; IEA:Ensembl.
//
ID   NKX24_HUMAN             Reviewed;         354 AA.
AC   Q9H2Z4; Q5VZV8;
DE   RecName: Full=Homeobox protein Nkx-2.4;
DE   AltName: Full=Homeobox protein NK-2 homolog D;
GN   Name=NKX2-4; Synonyms=NKX2D;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   NKX25_HUMAN             Reviewed;         324 AA.
AC   P52952; A8K3K0; B4DNB6; E9PBU6;
DE   RecName: Full=Homeobox protein Nkx-2.5;
DE   AltName: Full=Cardiac-specific homeobox;
DE   AltName: Full=Homeobox protein CSX;
DE   AltName: Full=Homeobox protein NK-2 homolog E;
GN   Name=NKX2-5; Synonyms=CSX, NKX2.5, NKX2E;
DR   GO; GO:0003682; F:chromatin binding; IDA:MGI.
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:Ensembl.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010736; F:serum response element binding; ISS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0007512; P:adult heart development; IMP:BHF-UCL.
DR   GO; GO:0003278; P:apoptotic process involved in heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0055014; P:atrial cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060928; P:atrioventricular node cell development; IEA:Ensembl.
DR   GO; GO:0060929; P:atrioventricular node cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0003166; P:bundle of His development; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0003161; P:cardiac conduction system development; IMP:MGI.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003211; P:cardiac ventricle formation; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0035050; P:embryonic heart tube development; ISS:BHF-UCL.
DR   GO; GO:0060971; P:embryonic heart tube left/right pattern formation; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.
DR   GO; GO:0051891; P:positive regulation of cardioblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0045823; P:positive regulation of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IMP:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0010735; P:positive regulation of transcription via serum response element binding; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:1901387; P:positive regulation of voltage-gated calcium channel activity; ISS:BHF-UCL.
DR   GO; GO:0003342; P:proepicardium development; IEA:Ensembl.
DR   GO; GO:0003350; P:pulmonary myocardium development; IEA:Ensembl.
DR   GO; GO:0003168; P:Purkinje myocyte differentiation; IEA:Ensembl.
DR   GO; GO:0060043; P:regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0003221; P:right ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0003285; P:septum secundum development; IMP:BHF-UCL.
DR   GO; GO:0048536; P:spleen development; IMP:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IMP:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0055005; P:ventricular cardiac myofibril assembly; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IEA:Ensembl.
//
ID   NKX26_HUMAN             Reviewed;         301 AA.
AC   A6NCS4;
DE   RecName: Full=Homeobox protein Nkx-2.6;
DE   AltName: Full=Homeobox protein NK-2 homolog F;
GN   Name=NKX2-6; Synonyms=NKX2F;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:HGNC.
DR   GO; GO:0055014; P:atrial cardiac muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; ISS:BHF-UCL.
DR   GO; GO:0035050; P:embryonic heart tube development; IMP:HGNC.
DR   GO; GO:0021854; P:hypothalamus development; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0060039; P:pericardium development; ISS:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0043586; P:tongue development; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; ISS:BHF-UCL.
//
ID   NKX28_HUMAN             Reviewed;         239 AA.
AC   O15522; Q8IUT7;
DE   RecName: Full=Homeobox protein Nkx-2.8;
DE   AltName: Full=Homeobox protein NK-2 homolog H;
GN   Name=NKX2-8; Synonyms=NKX-2.8, NKX2G, NKX2H;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; NAS:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   NKX31_HUMAN             Reviewed;         234 AA.
AC   Q99801; O15465; Q9H2P4; Q9H2P5; Q9H2P6; Q9H2P7; Q9HBG0;
DE   RecName: Full=Homeobox protein Nkx-3.1;
DE   AltName: Full=Homeobox protein NK-3 homolog A;
GN   Name=NKX3-1; Synonyms=NKX3.1, NKX3A;
DR   GO; GO:0004882; F:androgen receptor activity; IDA:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0030284; F:estrogen receptor activity; IDA:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060442; P:branching involved in prostate gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; ISS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IEP:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0035907; P:dorsal aorta development; IEA:Ensembl.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; ISS:UniProtKB.
DR   GO; GO:0071899; P:negative regulation of estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:2000836; P:positive regulation of androgen secretion; IDA:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:GOC.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0033574; P:response to testosterone; ISS:UniProtKB.
DR   GO; GO:0007431; P:salivary gland development; ISS:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; IDA:GOC.
//
ID   NKX32_HUMAN             Reviewed;         333 AA.
AC   P78367; Q2M2I7;
DE   RecName: Full=Homeobox protein Nkx-3.2;
DE   AltName: Full=Bagpipe homeobox protein homolog 1;
DE   AltName: Full=Homeobox protein NK-3 homolog B;
GN   Name=NKX3-2; Synonyms=BAPX1, NKX3B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0060576; P:intestinal epithelial cell development; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0048645; P:organ formation; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NKX61_HUMAN             Reviewed;         367 AA.
AC   P78426;
DE   RecName: Full=Homeobox protein Nkx-6.1;
DE   AltName: Full=Homeobox protein NK-6 homolog A;
GN   Name=NKX6-1; Synonyms=NKX6A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IEA:Ensembl.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0051594; P:detection of glucose; ISS:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0045686; P:negative regulation of glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0031016; P:pancreas development; ISS:BHF-UCL.
DR   GO; GO:0045687; P:positive regulation of glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:2000078; P:positive regulation of type B pancreatic cell development; ISS:BHF-UCL.
DR   GO; GO:0021912; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; IEA:Ensembl.
DR   GO; GO:0021913; P:regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0072560; P:type B pancreatic cell maturation; ISS:BHF-UCL.
//
ID   NKX62_HUMAN             Reviewed;         277 AA.
AC   Q9C056; Q5JSF3;
DE   RecName: Full=Homeobox protein Nkx-6.2;
DE   AltName: Full=Homeobox protein NK-6 homolog B;
GN   Name=NKX6-2; Synonyms=GTX, NKX6B;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0022010; P:central nervous system myelination; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0010454; P:negative regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0045686; P:negative regulation of glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0010455; P:positive regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0045687; P:positive regulation of glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0021912; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; IEA:Ensembl.
DR   GO; GO:0021913; P:regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   NKX63_HUMAN             Reviewed;         265 AA.
AC   A6NJ46; Q96LR0;
DE   RecName: Full=Homeobox protein Nkx-6.3;
GN   Name=NKX6-3;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001709; P:cell fate determination; IEA:Ensembl.
DR   GO; GO:0002067; P:glandular epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NLE1_HUMAN              Reviewed;         485 AA.
AC   Q9NVX2; O60868; Q59GJ8; Q9BU54;
DE   RecName: Full=Notchless protein homolog 1;
GN   Name=NLE1; ORFNames=HUSSY-07;
DR   GO; GO:0001826; P:inner cell mass cell differentiation; IEA:Ensembl.
DR   GO; GO:2001268; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
//
ID   NLGN1_HUMAN             Reviewed;         840 AA.
AC   Q8N2Q7; Q9UPT2;
DE   RecName: Full=Neuroligin-1;
DE   Flags: Precursor;
GN   Name=NLGN1; Synonyms=KIAA1070;
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProt.
DR   GO; GO:0046983; F:protein dimerization activity; ISS:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; ISS:BHF-UCL.
DR   GO; GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0048789; P:cytoskeletal matrix organization at active zone; ISS:BHF-UCL.
DR   GO; GO:0045184; P:establishment of protein localization; ISS:BHF-UCL.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0097114; P:N-methyl-D-aspartate receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
DR   GO; GO:0097115; P:neurexin clustering; ISS:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0023041; P:neuronal signal transduction; TAS:BHF-UCL.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:BHF-UCL.
DR   GO; GO:1902533; P:positive regulation of intracellular signal transduction; ISS:BHF-UCL.
DR   GO; GO:1900029; P:positive regulation of ruffle assembly; ISS:BHF-UCL.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:1900244; P:positive regulation of synaptic vesicle endocytosis; ISS:BHF-UCL.
DR   GO; GO:2000302; P:positive regulation of synaptic vesicle exocytosis; ISS:BHF-UCL.
DR   GO; GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:BHF-UCL.
DR   GO; GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.
DR   GO; GO:0006605; P:protein targeting; ISS:UniProtKB.
DR   GO; GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0045664; P:regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; ISS:UniProtKB.
DR   GO; GO:0097091; P:synaptic vesicle clustering; ISS:BHF-UCL.
DR   GO; GO:0016080; P:synaptic vesicle targeting; ISS:UniProtKB.
DR   GO; GO:0072553; P:terminal button organization; ISS:BHF-UCL.
//
ID   NLGN2_HUMAN             Reviewed;         835 AA.
AC   Q8NFZ4; Q9P2I1;
DE   RecName: Full=Neuroligin-2;
DE   Flags: Precursor;
GN   Name=NLGN2; Synonyms=KIAA1366;
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0042043; F:neurexin family protein binding; NAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045217; P:cell-cell junction maintenance; NAS:UniProtKB.
DR   GO; GO:0097116; P:gephyrin clustering; ISS:BHF-UCL.
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0097151; P:positive regulation of inhibitory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; ISS:BHF-UCL.
DR   GO; GO:0050804; P:regulation of synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; NAS:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; ISS:BHF-UCL.
DR   GO; GO:0072553; P:terminal button organization; ISS:BHF-UCL.
//
ID   NLGN3_HUMAN             Reviewed;         848 AA.
AC   Q9NZ94; B2RBK1; D2X2H6; D3DVV0; D3DVV1; Q86V51; Q8NCD0; Q9NZ95;
AC   Q9NZ96; Q9NZ97; Q9P248;
DE   RecName: Full=Neuroligin-3;
DE   AltName: Full=Gliotactin homolog;
DE   Flags: Precursor;
GN   Name=NLGN3; Synonyms=KIAA1480, NL3;
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0042043; F:neurexin family protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; ISS:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0048675; P:axon extension; ISS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; ISS:BHF-UCL.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; IEA:Ensembl.
DR   GO; GO:0060080; P:regulation of inhibitory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:1900271; P:regulation of long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; ISS:BHF-UCL.
DR   GO; GO:0050804; P:regulation of synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:2000331; P:regulation of terminal button organization; IEA:Ensembl.
DR   GO; GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:UniProtKB.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0050808; P:synapse organization; IMP:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   NLGNY_HUMAN             Reviewed;         816 AA.
AC   Q8NFZ3; F5H6W0; Q14D08; Q7Z3T5; Q8N5B6; Q9Y2F8;
DE   RecName: Full=Neuroligin-4, Y-linked;
DE            Short=Neuroligin Y;
DE   Flags: Precursor;
GN   Name=NLGN4Y; Synonyms=KIAA0951;
DR   GO; GO:0050839; F:cell adhesion molecule binding; TAS:BHF-UCL.
DR   GO; GO:0042043; F:neurexin family protein binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; IBA:RefGenome.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   NLGNX_HUMAN             Reviewed;         816 AA.
AC   Q8N0W4; Q6UX10; Q9ULG0;
DE   RecName: Full=Neuroligin-4, X-linked;
DE            Short=Neuroligin X;
DE   AltName: Full=HNLX;
DE   Flags: Precursor;
GN   Name=NLGN4X; Synonyms=KIAA1260, NLGN4; ORFNames=UNQ365/PRO701;
DR   GO; GO:0050839; F:cell adhesion molecule binding; TAS:BHF-UCL.
DR   GO; GO:0031404; F:chloride ion binding; IDA:UniProtKB.
DR   GO; GO:0042043; F:neurexin family protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0003360; P:brainstem development; ISS:BHF-UCL.
DR   GO; GO:0045216; P:cell-cell junction organization; NAS:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; ISS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IDA:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; NAS:BHF-UCL.
DR   GO; GO:0035265; P:organ growth; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; IDA:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; IMP:UniProtKB.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   NLK_HUMAN               Reviewed;         527 AA.
AC   Q9UBE8; B2RCX1; Q2PNI9; Q6P2A3;
DE   RecName: Full=Serine/threonine-protein kinase NLK;
DE            EC=2.7.11.24;
DE   AltName: Full=Nemo-like kinase;
DE   AltName: Full=Protein LAK1;
GN   Name=NLK; Synonyms=LAK1;
DR   GuidetoPHARMACOLOGY; 2125; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0004707; F:MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:Reactome.
DR   GO; GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NLRC3_HUMAN             Reviewed;        1065 AA.
AC   Q7RTR2; Q5EY36; Q8NF48; Q8NI01; Q8NI02; Q8TEL3;
DE   RecName: Full=Protein NLRC3;
DE   AltName: Full=CARD15-like protein;
DE   AltName: Full=Caterpiller protein 16.2;
DE            Short=CLR16.2;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 3;
GN   Name=NLRC3; Synonyms=NOD3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:MGI.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; IEP:UniProtKB.
//
ID   NLRC4_HUMAN             Reviewed;        1024 AA.
AC   Q9NPP4; A8K9F8; B2RBQ3; B3KTF0; D6W580; Q96J81; Q96J82; Q96J83;
DE   RecName: Full=NLR family CARD domain-containing protein 4;
DE   AltName: Full=CARD, LRR, and NACHT-containing protein;
DE            Short=Clan protein;
DE   AltName: Full=Caspase recruitment domain-containing protein 12;
DE   AltName: Full=Ice protease-activating factor;
DE            Short=Ipaf;
GN   Name=NLRC4; Synonyms=CARD12, CLAN, CLAN1, IPAF;
GN   ORFNames=UNQ6189/PRO20215;
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:HGNC.
DR   GO; GO:0002218; P:activation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:HGNC.
DR   GO; GO:0016045; P:detection of bacterium; IDA:HGNC.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050702; P:interleukin-1 beta secretion; IDA:HGNC.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0070269; P:pyroptosis; ISS:UniProtKB.
//
ID   NLRC5_HUMAN             Reviewed;        1866 AA.
AC   Q86WI3; B5MEF1; C9JMD8; Q6P4A6; Q86VM7; Q8NF42; Q8TEE2; Q8TEJ1;
AC   Q969L7;
DE   RecName: Full=Protein NLRC5;
DE   AltName: Full=Caterpiller protein 16.1;
DE            Short=CLR16.1;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 27;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 4;
GN   Name=NLRC5; Synonyms=NOD27, NOD4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0051607; P:defense response to virus; IEP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0060339; P:negative regulation of type I interferon-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060335; P:positive regulation of interferon-gamma-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045345; P:positive regulation of MHC class I biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043549; P:regulation of kinase activity; IDA:UniProtKB.
//
ID   NLRX1_HUMAN             Reviewed;         975 AA.
AC   Q86UT6; A8K6Q1; B3KPK2; B3KTA2; Q7RTR3; Q96D51; Q9H724;
DE   RecName: Full=NLR family member X1;
DE   AltName: Full=Caterpiller protein 11.3;
DE            Short=CLR11.3;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 26;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 5;
DE   AltName: Full=Nucleotide-binding oligomerization domain protein 9;
DE   Flags: Precursor;
GN   Name=NLRX1; Synonyms=NOD26, NOD5, NOD9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0045824; P:negative regulation of innate immune response; IEA:Ensembl.
DR   GO; GO:0032688; P:negative regulation of interferon-beta production; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0039536; P:negative regulation of RIG-I signaling pathway; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NLTP_HUMAN              Reviewed;         547 AA.
AC   P22307; A6NM69; B4DGJ9; B4DHP6; C9JC79; D3DQ37; E1B6W5; F2Z3J1;
AC   Q15432; Q16622; Q5VVZ1; Q6NXF4; Q99430;
DE   RecName: Full=Non-specific lipid-transfer protein;
DE            Short=NSL-TP;
DE            EC=2.3.1.176;
DE   AltName: Full=Propanoyl-CoA C-acyltransferase;
DE   AltName: Full=SCP-chi;
DE   AltName: Full=SCPX;
DE   AltName: Full=Sterol carrier protein 2;
DE            Short=SCP-2;
DE   AltName: Full=Sterol carrier protein X;
DE            Short=SCP-X;
GN   Name=SCP2;
DR   GO; GO:0015485; F:cholesterol binding; IDA:UniProtKB.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IDA:UniProtKB.
DR   GO; GO:0036042; F:long-chain fatty acyl-CoA binding; IDA:UniProtKB.
DR   GO; GO:0070538; F:oleic acid binding; IDA:UniProtKB.
DR   GO; GO:0008526; F:phosphatidylinositol transporter activity; IDA:UniProtKB.
DR   GO; GO:0033814; F:propanoyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0032959; P:inositol trisphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:1901373; P:lipid hydroperoxide transport; IDA:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0007031; P:peroxisome organization; IEA:Ensembl.
DR   GO; GO:0015914; P:phospholipid transport; IDA:UniProtKB.
DR   GO; GO:0032385; P:positive regulation of intracellular cholesterol transport; IDA:UniProtKB.
DR   GO; GO:0045940; P:positive regulation of steroid metabolic process; IDA:UniProtKB.
DR   GO; GO:0006701; P:progesterone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
//
ID   NMBR_HUMAN              Reviewed;         390 AA.
AC   P28336; E9KL38; Q5VUK8;
DE   RecName: Full=Neuromedin-B receptor;
DE            Short=NMB-R;
DE   AltName: Full=Epididymis tissue protein Li 185a;
DE   AltName: Full=Neuromedin-B-preferring bombesin receptor;
GN   Name=NMBR;
DR   GuidetoPHARMACOLOGY; 38; -.
DR   GO; GO:0004946; F:bombesin receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   NMB_HUMAN               Reviewed;         121 AA.
AC   P08949; Q96A06; Q96HH5;
DE   RecName: Full=Neuromedin-B;
DE   Contains:
DE     RecName: Full=Neuromedin-B-32;
DE   Contains:
DE     RecName: Full=Neuromedin-B;
DE   Flags: Precursor;
GN   Name=NMB;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NMD3A_HUMAN             Reviewed;        1115 AA.
AC   Q8TCU5; B3DLF9; Q5VTR3; Q8TF29; Q8WXI6;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 3A;
DE            Short=GluN3A;
DE   AltName: Full=N-methyl-D-aspartate receptor subtype 3A;
DE            Short=NMDAR3A;
DE            Short=NR3A;
DE   AltName: Full=NMDAR-L;
DE   Flags: Precursor;
GN   Name=GRIN3A; Synonyms=KIAA1973;
DR   GuidetoPHARMACOLOGY; 460; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0016594; F:glycine binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IDA:UniProtKB.
DR   GO; GO:0042165; F:neurotransmitter binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; ISS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   NMD3B_HUMAN             Reviewed;        1043 AA.
AC   O60391; Q5EAK7; Q7RTW9;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 3B;
DE            Short=GluN3B;
DE   AltName: Full=N-methyl-D-aspartate receptor subtype 3B;
DE            Short=NMDAR3B;
DE            Short=NR3B;
DE   Flags: Precursor;
GN   Name=GRIN3B;
DR   GuidetoPHARMACOLOGY; 461; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005261; F:cation channel activity; ISS:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0016594; F:glycine binding; ISS:UniProtKB.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0042165; F:neurotransmitter binding; ISS:UniProtKB.
DR   GO; GO:0030594; F:neurotransmitter receptor activity; ISS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0051205; P:protein insertion into membrane; ISS:UniProtKB.
DR   GO; GO:0051924; P:regulation of calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   NMD3_HUMAN              Reviewed;         503 AA.
AC   Q96D46; D3DNM7; Q9Y2Z6;
DE   RecName: Full=60S ribosomal export protein NMD3;
DE            Short=hNMD3;
GN   Name=NMD3; ORFNames=CGI-07;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NMDE1_HUMAN             Reviewed;        1464 AA.
AC   Q12879; O00669; Q17RZ6;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 2A;
DE            Short=GluN2A;
DE   AltName: Full=Glutamate [NMDA] receptor subunit epsilon-1;
DE   AltName: Full=N-methyl D-aspartate receptor subtype 2A;
DE            Short=NMDAR2A;
DE            Short=NR2A;
DE            Short=hNR2A;
DE   Flags: Precursor;
GN   Name=GRIN2A; Synonyms=NMDAR2A;
DR   GuidetoPHARMACOLOGY; 456; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0033058; P:directional locomotion; IEA:Ensembl.
DR   GO; GO:0042417; P:dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007611; P:learning or memory; TAS:ProtInc.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0042428; P:serotonin metabolic process; IEA:Ensembl.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   NMDE2_HUMAN             Reviewed;        1484 AA.
AC   Q13224; Q12919; Q13220; Q13225; Q14CU4; Q9UM56;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 2B;
DE            Short=GluN2B;
DE   AltName: Full=Glutamate [NMDA] receptor subunit epsilon-2;
DE   AltName: Full=N-methyl D-aspartate receptor subtype 2B;
DE            Short=NMDAR2B;
DE            Short=NR2B;
DE   AltName: Full=N-methyl-D-aspartate receptor subunit 3;
DE            Short=NR3;
DE            Short=hNR3;
DE   Flags: Precursor;
GN   Name=GRIN2B; Synonyms=NMDAR2B;
DR   GuidetoPHARMACOLOGY; 457; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0016594; F:glycine binding; IDA:UniProtKB.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007611; P:learning or memory; TAS:ProtInc.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0007423; P:sensory organ development; IEA:Ensembl.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   NMDE3_HUMAN             Reviewed;        1233 AA.
AC   Q14957; B2RTT1;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 2C;
DE            Short=GluN2C;
DE   AltName: Full=Glutamate [NMDA] receptor subunit epsilon-3;
DE   AltName: Full=N-methyl D-aspartate receptor subtype 2C;
DE            Short=NMDAR2C;
DE            Short=NR2C;
DE   Flags: Precursor;
GN   Name=GRIN2C; Synonyms=NMDAR2C;
DR   GuidetoPHARMACOLOGY; 458; -.
DR   GO; GO:0005261; F:cation channel activity; IEA:Ensembl.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033058; P:directional locomotion; IEA:Ensembl.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   NMDE4_HUMAN             Reviewed;        1336 AA.
AC   O15399;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 2D;
DE            Short=GluN2D;
DE   AltName: Full=EB11;
DE   AltName: Full=Glutamate [NMDA] receptor subunit epsilon-4;
DE   AltName: Full=N-methyl D-aspartate receptor subtype 2D;
DE            Short=NMDAR2D;
DE            Short=NR2D;
DE   Flags: Precursor;
GN   Name=GRIN2D; Synonyms=GluN2D, NMDAR2D;
DR   GuidetoPHARMACOLOGY; 459; -.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
//
ID   NMDZ1_HUMAN             Reviewed;         938 AA.
AC   Q05586; A6NLK7; A6NLR1; C9K0X1; P35437; Q12867; Q12868; Q5VSF3;
AC   Q5VSF4; Q5VSF5; Q5VSF6; Q5VSF7; Q5VSF8; Q9UPF8; Q9UPF9;
DE   RecName: Full=Glutamate receptor ionotropic, NMDA 1;
DE            Short=GluN1;
DE   AltName: Full=Glutamate [NMDA] receptor subunit zeta-1;
DE   AltName: Full=N-methyl-D-aspartate receptor subunit NR1;
DE            Short=NMD-R1;
DE   Flags: Precursor;
GN   Name=GRIN1; Synonyms=NMDAR1;
DR   GuidetoPHARMACOLOGY; 455; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; ISS:UniProtKB.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; IBA:RefGenome.
DR   GO; GO:0016595; F:glutamate binding; IDA:UniProtKB.
DR   GO; GO:0016594; F:glycine binding; IDA:UniProtKB.
DR   GO; GO:0004972; F:N-methyl-D-aspartate selective glutamate receptor activity; IEA:Ensembl.
DR   GO; GO:0042165; F:neurotransmitter binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0022843; F:voltage-gated cation channel activity; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0055074; P:calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0006812; P:cation transport; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071287; P:cellular response to manganese ion; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0001661; P:conditioned taste aversion; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0035235; P:ionotropic glutamate receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0060179; P:male mating behavior; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0008355; P:olfactory learning; IEA:Ensembl.
DR   GO; GO:0021586; P:pons maturation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
DR   GO; GO:0018964; P:propylene metabolic process; ISS:BHF-UCL.
DR   GO; GO:0051262; P:protein tetramerization; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; ISS:UniProtKB.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:UniProtKB.
DR   GO; GO:0043576; P:regulation of respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0051963; P:regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IDA:UniProtKB.
DR   GO; GO:0060992; P:response to fungicide; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0048511; P:rhythmic process; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IBA:RefGenome.
DR   GO; GO:0008542; P:visual learning; ISS:UniProtKB.
//
ID   NMES1_HUMAN             Reviewed;          83 AA.
AC   Q9C002;
DE   RecName: Full=Normal mucosa of esophagus-specific gene 1 protein;
DE   AltName: Full=Protein FOAP-11;
GN   Name=NMES1; Synonyms=C15orf48;
//
ID   NMI_HUMAN               Reviewed;         307 AA.
AC   Q13287; B5BU69; Q53TI8; Q9BVE5;
DE   RecName: Full=N-myc-interactor;
DE            Short=Nmi;
DE   AltName: Full=N-myc and STAT interactor;
GN   Name=NMI;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NMNA1_HUMAN             Reviewed;         279 AA.
AC   Q9HAN9; B1AN63; Q8TAE9; Q9H247; Q9H6B6;
DE   RecName: Full=Nicotinamide mononucleotide adenylyltransferase 1;
DE            Short=NMN adenylyltransferase 1;
DE            EC=2.7.7.1;
DE   AltName: Full=Nicotinate-nucleotide adenylyltransferase 1;
DE            Short=NaMN adenylyltransferase 1;
DE            EC=2.7.7.18;
GN   Name=NMNAT1; Synonyms=NMNAT;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009435; P:NAD biosynthetic process; IC:UniProtKB.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NMNA2_HUMAN             Reviewed;         307 AA.
AC   Q9BZQ4; O75067; Q5T1Q3; Q8WU99; Q96QW1;
DE   RecName: Full=Nicotinamide mononucleotide adenylyltransferase 2;
DE            Short=NMN adenylyltransferase 2;
DE            EC=2.7.7.1;
DE   AltName: Full=Nicotinate-nucleotide adenylyltransferase 2;
DE            Short=NaMN adenylyltransferase 2;
DE            EC=2.7.7.18;
GN   Name=NMNAT2; Synonyms=C1orf15, KIAA0479;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; TAS:Reactome.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0009435; P:NAD biosynthetic process; IC:UniProtKB.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NMNA3_HUMAN             Reviewed;         252 AA.
AC   Q96T66; B3KVR6; D3DNF2; D3DNF3; Q8N4G1;
DE   RecName: Full=Nicotinamide mononucleotide adenylyltransferase 3;
DE            Short=NMN adenylyltransferase 3;
DE   AltName: Full=Nicotinate-nucleotide adenylyltransferase 3;
DE            Short=NaMN adenylyltransferase 3;
DE            EC=2.7.7.18;
DE   AltName: Full=Pyridine nucleotide adenylyltransferase 3;
DE            Short=PNAT-3;
DE            EC=2.7.7.1;
GN   Name=NMNAT3; ORFNames=FKSG76;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; TAS:Reactome.
DR   GO; GO:0004515; F:nicotinate-nucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0009435; P:NAD biosynthetic process; IC:UniProtKB.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   NMRL1_HUMAN             Reviewed;         299 AA.
AC   Q9HBL8;
DE   RecName: Full=NmrA-like family domain-containing protein 1;
GN   Name=NMRAL1; Synonyms=HSCARG;
//
ID   NMS_HUMAN               Reviewed;         153 AA.
AC   Q5H8A3;
DE   RecName: Full=Neuromedin-S;
DE   Flags: Precursor;
GN   Name=NMS;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
//
ID   NMT1_HUMAN              Reviewed;         496 AA.
AC   P30419; A8K7C1; Q9UE09;
DE   RecName: Full=Glycylpeptide N-tetradecanoyltransferase 1;
DE            EC=2.3.1.97;
DE   AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase 1;
DE            Short=NMT 1;
DE            Short=Type I N-myristoyltransferase;
DE   AltName: Full=Peptide N-myristoyltransferase 1;
GN   Name=NMT1; Synonyms=NMT;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0004379; F:glycylpeptide N-tetradecanoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006499; P:N-terminal protein myristoylation; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0009249; P:protein lipoylation; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NMT2_HUMAN              Reviewed;         498 AA.
AC   O60551; B0YJ49; Q53Y38; Q5VUC8; Q9BRB4;
DE   RecName: Full=Glycylpeptide N-tetradecanoyltransferase 2;
DE            EC=2.3.1.97;
DE   AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase 2;
DE            Short=NMT 2;
DE   AltName: Full=Peptide N-myristoyltransferase 2;
DE   AltName: Full=Type II N-myristoyltransferase;
GN   Name=NMT2;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0004379; F:glycylpeptide N-tetradecanoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0006499; P:N-terminal protein myristoylation; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0009249; P:protein lipoylation; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   NMUR1_HUMAN             Reviewed;         426 AA.
AC   Q9HB89; O43664; Q7LDP6; Q8NE20;
DE   RecName: Full=Neuromedin-U receptor 1;
DE            Short=NMU-R1;
DE   AltName: Full=G-protein coupled receptor 66;
DE   AltName: Full=G-protein coupled receptor FM-3;
GN   Name=NMUR1; Synonyms=GPR66;
DR   GuidetoPHARMACOLOGY; 298; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:UniProtKB.
DR   GO; GO:0001607; F:neuromedin U receptor activity; IDA:UniProtKB.
DR   GO; GO:0008188; F:neuropeptide receptor activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0006821; P:chloride transport; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006939; P:smooth muscle contraction; IEP:UniProtKB.
//
ID   NMUR2_HUMAN             Reviewed;         415 AA.
AC   Q9GZQ4; Q7LC54; Q96AM5; Q9NRA6;
DE   RecName: Full=Neuromedin-U receptor 2;
DE            Short=NMU-R2;
DE   AltName: Full=G-protein coupled receptor FM-4;
DE   AltName: Full=G-protein coupled receptor TGR-1;
GN   Name=NMUR2; Synonyms=NMU2R, TGR1;
DR   GuidetoPHARMACOLOGY; 299; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0005229; F:intracellular calcium activated chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0042924; F:neuromedin U binding; IDA:UniProtKB.
DR   GO; GO:0001607; F:neuromedin U receptor activity; IDA:UniProtKB.
DR   GO; GO:0043006; P:activation of phospholipase A2 activity by calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; IEP:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:GOC.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0002023; P:reduction of food intake in response to dietary excess; IEA:Ensembl.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; NAS:UniProtKB.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
//
ID   NMU_HUMAN               Reviewed;         174 AA.
AC   P48645;
DE   RecName: Full=Neuromedin-U;
DE   Contains:
DE     RecName: Full=Neuromedin-U-25;
DE              Short=NmU-25;
DE   Flags: Precursor;
GN   Name=NMU;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001696; P:gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0009648; P:photoperiodism; IEA:Ensembl.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; TAS:ProtInc.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NNAT_HUMAN              Reviewed;          81 AA.
AC   Q16517; B2R558; E1P5V6; Q16596; Q5U0N3;
DE   RecName: Full=Neuronatin;
GN   Name=NNAT;
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0009249; P:protein lipoylation; TAS:ProtInc.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   NNMT_HUMAN              Reviewed;         264 AA.
AC   P40261;
DE   RecName: Full=Nicotinamide N-methyltransferase;
DE            EC=2.1.1.1;
GN   Name=NNMT;
DR   GO; GO:0008112; F:nicotinamide N-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   NNRD_HUMAN              Reviewed;         347 AA.
AC   Q8IW45; B4DXT4; Q5T9X3; Q9H7W1; Q9NVF5;
DE   RecName: Full=ATP-dependent (S)-NAD(P)H-hydrate dehydratase;
DE            EC=4.2.1.93;
DE   AltName: Full=ATP-dependent NAD(P)HX dehydratase;
DE   AltName: Full=Carbohydrate kinase domain-containing protein;
DE   Flags: Precursor;
GN   Name=CARKD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047453; F:ATP-dependent NAD(P)H-hydrate dehydratase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0046496; P:nicotinamide nucleotide metabolic process; IEA:UniProtKB-HAMAP.
//
ID   NNRE_HUMAN              Reviewed;         288 AA.
AC   Q8NCW5; B4DGY3; Q496C6; Q5T3I2;
DE   RecName: Full=NAD(P)H-hydrate epimerase;
DE            EC=5.1.99.6;
DE   AltName: Full=Apolipoprotein A-I-binding protein;
DE            Short=AI-BP;
DE   AltName: Full=NAD(P)HX epimerase;
DE   AltName: Full=YjeF N-terminal domain-containing protein 1;
DE            Short=YjeF_N1;
DE   Flags: Precursor;
GN   Name=APOA1BP; Synonyms=AIBP, YJEFN1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0052856; F:NADHX epimerase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
//
ID   NNTM_HUMAN              Reviewed;        1086 AA.
AC   Q13423; Q16796; Q2TB60; Q8N3V4;
DE   RecName: Full=NAD(P) transhydrogenase, mitochondrial;
DE            EC=1.6.1.2;
DE   AltName: Full=Nicotinamide nucleotide transhydrogenase;
DE   AltName: Full=Pyridine nucleotide transhydrogenase;
DE   Flags: Precursor;
GN   Name=NNT;
DR   GO; GO:0051287; F:NAD binding; TAS:UniProtKB.
DR   GO; GO:0008750; F:NAD(P)+ transhydrogenase (AB-specific) activity; IEA:UniProtKB-EC.
DR   GO; GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; TAS:UniProtKB.
DR   GO; GO:0008746; F:NAD(P)+ transhydrogenase activity; EXP:Reactome.
DR   GO; GO:0050661; F:NADP binding; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0015992; P:proton transport; TAS:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:UniProtKB.
//
ID   NO40_HUMAN              Reviewed;         241 AA.
AC   Q9NP64; B4DY38; D3DPN4; Q6PKH4; Q9NYG4; Q9P0M8;
DE   RecName: Full=Nucleolar protein of 40 kDa;
DE            Short=pNO40;
DE   AltName: Full=Pnn-interacting nucleolar protein;
DE   AltName: Full=Putative S1 RNA-binding domain protein;
DE            Short=PS1D protein;
DE   AltName: Full=Zinc finger CCHC domain-containing protein 17;
GN   Name=ZCCHC17; Synonyms=PS1D; ORFNames=HSPC243, HSPC251, LDC4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   NO66_HUMAN              Reviewed;         641 AA.
AC   Q9H6W3; B4DT02;
DE   RecName: Full=Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66;
DE            EC=1.14.11.-;
DE            EC=1.14.11.27;
DE   AltName: Full=60S ribosomal protein L8 histidine hydroxylase;
DE   AltName: Full=Histone lysine demethylase NO66;
DE   AltName: Full=Myc-associated protein with JmjC domain;
DE   AltName: Full=Nucleolar protein 66;
DE            Short=hsNO66;
DE   AltName: Full=Ribosomal oxygenase NO66;
DE            Short=ROX;
GN   Name=NO66; Synonyms=C14orf169, MAPJD;
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.
DR   GO; GO:0032453; F:histone demethylase activity (H3-K4 specific); ISS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; ISS:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070544; P:histone H3-K36 demethylation; ISS:UniProtKB.
DR   GO; GO:0034720; P:histone H3-K4 demethylation; ISS:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NOB1_HUMAN              Reviewed;         412 AA.
AC   Q9ULX3; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0;
DE   RecName: Full=RNA-binding protein NOB1;
DE   AltName: Full=Phosphorylation regulatory protein HP-10;
DE   AltName: Full=Protein ART-4;
GN   Name=NOB1; Synonyms=ART4, NOB1P, PSMD8BP1; ORFNames=MSTP158;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   NOBOX_HUMAN             Reviewed;         691 AA.
AC   O60393; A6NCD3; A8MZN5;
DE   RecName: Full=Homeobox protein NOBOX;
GN   Name=NOBOX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NOA1_HUMAN              Reviewed;         698 AA.
AC   Q8NC60; Q8N7L6; Q9BSQ9;
DE   RecName: Full=Nitric oxide-associated protein 1;
GN   Name=NOA1; Synonyms=C4orf14;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IBA:RefGenome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IBA:GOC.
DR   GO; GO:0032543; P:mitochondrial translation; ISS:UniProtKB.
DR   GO; GO:0010941; P:regulation of cell death; IMP:UniProtKB.
DR   GO; GO:0043457; P:regulation of cellular respiration; IMP:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
//
ID   NOC2L_HUMAN             Reviewed;         749 AA.
AC   Q9Y3T9; Q5SVA3; Q9BTN6;
DE   RecName: Full=Nucleolar complex protein 2 homolog;
DE            Short=Protein NOC2 homolog;
DE   AltName: Full=NOC2-like protein;
DE   AltName: Full=Novel INHAT repressor;
GN   Name=NOC2L; Synonyms=NIR;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0031491; F:nucleosome binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0031497; P:chromatin assembly; IDA:UniProtKB.
DR   GO; GO:0002903; P:negative regulation of B cell apoptotic process; IMP:UniProtKB.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IDA:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032066; P:nucleolus to nucleoplasm transport; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NOC3L_HUMAN             Reviewed;         800 AA.
AC   Q8WTT2; Q9H5M6; Q9H9D8;
DE   RecName: Full=Nucleolar complex protein 3 homolog;
DE            Short=NOC3 protein homolog;
DE   AltName: Full=Factor for adipocyte differentiation 24;
DE   AltName: Full=NOC3-like protein;
DE   AltName: Full=Nucleolar complex-associated protein 3-like protein;
GN   Name=NOC3L; Synonyms=AD24, C10orf117, FAD24;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
//
ID   NOC4L_HUMAN             Reviewed;         516 AA.
AC   Q9BVI4; Q8N2S5; Q96I14;
DE   RecName: Full=Nucleolar complex protein 4 homolog;
DE            Short=NOC4 protein homolog;
DE   AltName: Full=NOC4-like protein;
DE   AltName: Full=Nucleolar complex-associated protein 4-like protein;
GN   Name=NOC4L;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
//
ID   NOCT_HUMAN              Reviewed;         431 AA.
AC   Q9UK39; D3DNY5; Q14D51; Q9HD93; Q9HD94; Q9HD95;
DE   RecName: Full=Nocturnin;
DE            EC=3.1.13.4;
DE   AltName: Full=Carbon catabolite repression 4-like protein;
DE   AltName: Full=Circadian deadenylase NOC;
GN   Name=CCRN4L; Synonyms=CCR4, NOC;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IEA:Ensembl.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   NOD1_HUMAN              Reviewed;         953 AA.
AC   Q9Y239; Q549U4; Q8IWF5;
DE   RecName: Full=Nucleotide-binding oligomerization domain-containing protein 1;
DE   AltName: Full=Caspase recruitment domain-containing protein 4;
GN   Name=NOD1; Synonyms=CARD4;
DR   GuidetoPHARMACOLOGY; 1762; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050700; F:CARD domain binding; IDA:MGI.
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0042834; F:peptidoglycan binding; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:HGNC.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:HGNC.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0016045; P:detection of bacterium; IDA:HGNC.
DR   GO; GO:0009595; P:detection of biotic stimulus; TAS:HGNC.
DR   GO; GO:0006954; P:inflammatory response; TAS:HGNC.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0042228; P:interleukin-8 biosynthetic process; IDA:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:MGI.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; TAS:HGNC.
DR   GO; GO:0007165; P:signal transduction; TAS:HGNC.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   NOD2_HUMAN              Reviewed;        1040 AA.
AC   Q9HC29; E2JEQ6; Q96RH5; Q96RH6; Q96RH8;
DE   RecName: Full=Nucleotide-binding oligomerization domain-containing protein 2;
DE   AltName: Full=Caspase recruitment domain-containing protein 15;
DE   AltName: Full=Inflammatory bowel disease protein 1;
GN   Name=NOD2; Synonyms=CARD15, IBD1;
DR   GuidetoPHARMACOLOGY; 1763; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050700; F:CARD domain binding; IPI:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0032500; F:muramyl dipeptide binding; IDA:HGNC.
DR   GO; GO:0042834; F:peptidoglycan binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0035419; P:activation of MAPK activity involved in innate immune response; ISS:BHF-UCL.
DR   GO; GO:0071225; P:cellular response to muramyl dipeptide; IDA:UniProtKB.
DR   GO; GO:0071224; P:cellular response to peptidoglycan; IEA:Ensembl.
DR   GO; GO:0002367; P:cytokine production involved in immune response; IMP:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:HGNC.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:HGNC.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0016045; P:detection of bacterium; IDA:HGNC.
DR   GO; GO:0009595; P:detection of biotic stimulus; TAS:HGNC.
DR   GO; GO:0032498; P:detection of muramyl dipeptide; IDA:HGNC.
DR   GO; GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0002227; P:innate immune response in mucosa; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0071608; P:macrophage inflammatory protein-1 alpha production; IEA:Ensembl.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProt.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032701; P:negative regulation of interleukin-18 production; IEA:Ensembl.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:2000110; P:negative regulation of macrophage apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0002710; P:negative regulation of T cell mediated immunity; IEA:Ensembl.
DR   GO; GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0052033; P:pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; IEA:Ensembl.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IDA:BHF-UCL.
DR   GO; GO:0006965; P:positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria; IEA:Ensembl.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.
DR   GO; GO:0002732; P:positive regulation of dendritic cell cytokine production; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0046645; P:positive regulation of gamma-delta T cell activation; ISS:BHF-UCL.
DR   GO; GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; IMP:BHF-UCL.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IMP:UniProtKB.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:MGI.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0051353; P:positive regulation of oxidoreductase activity; ISS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:BHF-UCL.
DR   GO; GO:2000363; P:positive regulation of prostaglandin-E synthase activity; ISS:BHF-UCL.
DR   GO; GO:0060585; P:positive regulation of prostaglandin-endoperoxide synthase activity; ISS:BHF-UCL.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0002830; P:positive regulation of type 2 immune response; IMP:BHF-UCL.
DR   GO; GO:0051259; P:protein oligomerization; TAS:HGNC.
DR   GO; GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0090022; P:regulation of neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IDA:BHF-UCL.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   NODAL_HUMAN             Reviewed;         347 AA.
AC   Q96S42; Q2M3A5; Q8N4V3;
DE   RecName: Full=Nodal homolog;
DE   Flags: Precursor;
GN   Name=NODAL;
DR   GO; GO:0016015; F:morphogen activity; NAS:BHF-UCL.
DR   GO; GO:0070698; F:type I activin receptor binding; IMP:BHF-UCL.
DR   GO; GO:0048327; P:axial mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0035987; P:endodermal cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0060802; P:epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0033505; P:floor plate morphogenesis; IEA:Ensembl.
DR   GO; GO:0048859; P:formation of anatomical boundary; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:InterPro.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0002085; P:inhibition of neuroepithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060460; P:left lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0048382; P:mesendoderm development; IMP:BHF-UCL.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:1901383; P:negative regulation of chorionic trophoblast cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:1901164; P:negative regulation of trophoblast cell migration; IDA:BHF-UCL.
DR   GO; GO:0001842; P:neural fold formation; IEA:Ensembl.
DR   GO; GO:1900164; P:nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IMP:BHF-UCL.
DR   GO; GO:0010085; P:polarity specification of proximal/distal axis; IEA:Ensembl.
DR   GO; GO:0032927; P:positive regulation of activin receptor signaling pathway; IGI:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.
DR   GO; GO:1900224; P:positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; ISS:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IMP:BHF-UCL.
DR   GO; GO:0010470; P:regulation of gastrulation; IEA:Ensembl.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; TAS:BHF-UCL.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0090010; P:transforming growth factor beta receptor signaling pathway involved in primitive streak formation; IEA:Ensembl.
DR   GO; GO:0001831; P:trophectodermal cellular morphogenesis; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IEA:Ensembl.
//
ID   NOE1_HUMAN              Reviewed;         485 AA.
AC   Q99784; Q53XZ8; Q6IMJ4; Q969S7; Q99452;
DE   RecName: Full=Noelin;
DE   AltName: Full=Neuronal olfactomedin-related ER localized protein;
DE   AltName: Full=Olfactomedin-1;
DE   Flags: Precursor;
GN   Name=OLFM1; Synonyms=NOE1, NOEL1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
//
ID   NOE2_HUMAN              Reviewed;         454 AA.
AC   O95897; Q6IMJ3; Q96FC2;
DE   RecName: Full=Noelin-2;
DE   AltName: Full=Olfactomedin-2;
DE   Flags: Precursor;
GN   Name=OLFM2; Synonyms=NOE2;
DR   GO; GO:0009306; P:protein secretion; IDA:MGI.
//
ID   NOE3_HUMAN              Reviewed;         478 AA.
AC   Q96PB7; Q5T3V6; Q6IMI7; Q6IMI8; Q6IMI9; Q6IMJ1; Q8TBG1; Q96PB2;
AC   Q96PB3; Q96PB4; Q96PB5; Q96PB6;
DE   RecName: Full=Noelin-3;
DE   AltName: Full=Olfactomedin-3;
DE   AltName: Full=Optimedin;
DE   Flags: Precursor;
GN   Name=OLFM3; Synonyms=NOE3; ORFNames=UNQ1924/PRO4399;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
//
ID   NOG1_HUMAN              Reviewed;         634 AA.
AC   Q9BZE4; B3KMC5; O95446; Q5T3R8; Q9NVJ8;
DE   RecName: Full=Nucleolar GTP-binding protein 1;
DE   AltName: Full=Chronic renal failure gene protein;
DE   AltName: Full=GTP-binding protein NGB;
GN   Name=GTPBP4; Synonyms=CRFG, NOG1;
DR   GO; GO:0005525; F:GTP binding; IDA:HGNC.
DR   GO; GO:0003924; F:GTPase activity; IDA:HGNC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:HGNC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IDA:HGNC.
DR   GO; GO:0033342; P:negative regulation of collagen binding; IMP:HGNC.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:HGNC.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:HGNC.
DR   GO; GO:0050821; P:protein stabilization; IDA:HGNC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   NOG2_HUMAN              Reviewed;         731 AA.
AC   Q13823; Q9BWN7;
DE   RecName: Full=Nucleolar GTP-binding protein 2;
DE   AltName: Full=Autoantigen NGP-1;
GN   Name=GNL2; Synonyms=NGP1;
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IBA:GOC.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
//
ID   NOGG_HUMAN              Reviewed;         232 AA.
AC   Q13253;
DE   RecName: Full=Noggin;
DE   Flags: Precursor;
GN   Name=NOG;
DR   GO; GO:0019955; F:cytokine binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0048318; P:axial mesoderm development; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0021533; P:cell differentiation in hindbrain; IMP:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IDA:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.
DR   GO; GO:0001706; P:endoderm formation; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0060825; P:fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060173; P:limb development; IMP:BHF-UCL.
DR   GO; GO:0060425; P:lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0060302; P:negative regulation of cytokine activity; IPI:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001839; P:neural plate morphogenesis; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0048570; P:notochord morphogenesis; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0090193; P:positive regulation of glomerulus development; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060513; P:prostatic bud formation; IEA:Ensembl.
DR   GO; GO:2000313; P:regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IMP:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IMP:BHF-UCL.
DR   GO; GO:0061053; P:somite development; IEA:Ensembl.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0060676; P:ureteric bud formation; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
//
ID   NOL10_HUMAN             Reviewed;         688 AA.
AC   Q9BSC4; A8K3R5; B4DLV0; Q53RC9; Q96TA5; Q9H7Y7; Q9H855;
DE   RecName: Full=Nucleolar protein 10;
GN   Name=NOL10;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NOL11_HUMAN             Reviewed;         719 AA.
AC   Q9H8H0; B7Z5V9; Q7L5S1; Q9UG18;
DE   RecName: Full=Nucleolar protein 11;
GN   Name=NOL11; ORFNames=L14;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IMP:UniProtKB.
DR   GO; GO:1901838; P:positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NOL12_HUMAN             Reviewed;         213 AA.
AC   Q9UGY1;
DE   RecName: Full=Nucleolar protein 12;
GN   Name=NOL12;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
//
ID   NOL3_HUMAN              Reviewed;         219 AA.
AC   O60936; B4DFL0; O60937;
DE   RecName: Full=Nucleolar protein 3;
DE   AltName: Full=Apoptosis repressor with CARD;
DE   AltName: Full=Muscle-enriched cytoplasmic protein;
DE            Short=Myp;
DE   AltName: Full=Nucleolar protein of 30 kDa;
DE            Short=Nop30;
GN   Name=NOL3; Synonyms=ARC, NOP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   NOL4_HUMAN              Reviewed;         638 AA.
AC   O94818; B4DSQ0; B7Z3Z7; F5H1E3; Q6IBS2; Q9BWF1;
DE   RecName: Full=Nucleolar protein 4;
DE   AltName: Full=Nucleolar-localized protein;
GN   Name=NOL4; Synonyms=NOLP; ORFNames=HRIHFB2255;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
//
ID   NOL7_HUMAN              Reviewed;         257 AA.
AC   Q9UMY1; Q5T297; Q9Y3U7;
DE   RecName: Full=Nucleolar protein 7;
DE   AltName: Full=Nucleolar protein of 27 kDa;
GN   Name=NOL7; Synonyms=C6orf90, NOP27;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NOL8_HUMAN              Reviewed;        1167 AA.
AC   Q76FK4; Q5TCC7; Q5TCC8; Q5TCD3; Q5TCD5; Q5TCD6; Q5TCD7; Q76D35;
AC   Q7L3E2; Q9H586; Q9H795; Q9H7W7; Q9H9J6; Q9NWA4; Q9NWM4;
DE   RecName: Full=Nucleolar protein 8;
DE   AltName: Full=Nucleolar protein Nop132;
GN   Name=NOL8; Synonyms=C9orf34, NOP132;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IMP:HGNC.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:HGNC.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
//
ID   NOL6_HUMAN              Reviewed;        1146 AA.
AC   Q9H6R4; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1;
AC   Q9H675;
DE   RecName: Full=Nucleolar protein 6;
DE   AltName: Full=Nucleolar RNA-associated protein;
DE            Short=Nrap;
GN   Name=NOL6;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
//
ID   NOL9_HUMAN              Reviewed;         702 AA.
AC   Q5SY16; Q2NL84; Q4VBY3; Q6P472; Q7L4D6; Q96EE0; Q9H5L4;
DE   RecName: Full=Polynucleotide 5'-hydroxyl-kinase NOL9;
DE            EC=2.7.1.-;
DE   AltName: Full=Nucleolar protein 9;
GN   Name=NOL9;
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
//
ID   NOLC1_HUMAN             Reviewed;         699 AA.
AC   Q14978; Q15030; Q5VV70; Q9BUV3;
DE   RecName: Full=Nucleolar and coiled-body phosphoprotein 1;
DE   AltName: Full=140 kDa nucleolar phosphoprotein;
DE            Short=Nopp140;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 13;
DE            Short=HCV NS5A-transactivated protein 13;
DE   AltName: Full=Nucleolar 130 kDa protein;
DE   AltName: Full=Nucleolar phosphoprotein p130;
GN   Name=NOLC1; Synonyms=KIAA0035, NS5ATP13;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0007000; P:nucleolus organization; IEA:Ensembl.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
//
ID   NOM1_HUMAN              Reviewed;         860 AA.
AC   Q5C9Z4; Q96I08;
DE   RecName: Full=Nucleolar MIF4G domain-containing protein 1;
DE   AltName: Full=SGD1 homolog;
GN   Name=NOM1; Synonyms=C7orf3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   NOMO1_HUMAN             Reviewed;        1222 AA.
AC   Q15155; P78421; Q8IW21; Q96DG0;
DE   RecName: Full=Nodal modulator 1;
DE   AltName: Full=pM5 protein;
DE   Flags: Precursor;
GN   Name=NOMO1; Synonyms=PM5;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   NOMO3_HUMAN             Reviewed;        1222 AA.
AC   P69849;
DE   RecName: Full=Nodal modulator 3;
DE   AltName: Full=pM5 protein 3;
DE   Flags: Precursor;
GN   Name=NOMO3;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   NOMO2_HUMAN             Reviewed;        1267 AA.
AC   Q5JPE7; Q4G177;
DE   RecName: Full=Nodal modulator 2;
DE   AltName: Full=pM5 protein 2;
DE   Flags: Precursor;
GN   Name=NOMO2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   NONO_HUMAN              Reviewed;         471 AA.
AC   Q15233; B7Z4C2; D3DVV4; F5GYZ3; O00201; P30807; Q12786; Q9BQC5;
DE   RecName: Full=Non-POU domain-containing octamer-binding protein;
DE            Short=NonO protein;
DE   AltName: Full=54 kDa nuclear RNA- and DNA-binding protein;
DE   AltName: Full=55 kDa nuclear protein;
DE   AltName: Full=DNA-binding p52/p100 complex, 52 kDa subunit;
DE   AltName: Full=NMT55;
DE   AltName: Full=p54(nrb);
DE            Short=p54nrb;
GN   Name=NONO; Synonyms=NRB54;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NOP10_HUMAN             Reviewed;          64 AA.
AC   Q9NPE3;
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit 3;
DE   AltName: Full=Nucleolar protein 10;
DE   AltName: Full=Nucleolar protein family A member 3;
DE   AltName: Full=snoRNP protein NOP10;
GN   Name=NOP10; Synonyms=NOLA3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; NAS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   NOP14_HUMAN             Reviewed;         857 AA.
AC   P78316; D3DVR6; Q7LGI5; Q7Z6K0; Q8TBR6;
DE   RecName: Full=Nucleolar protein 14;
DE   AltName: Full=Nucleolar complex protein 14;
GN   Name=NOP14; Synonyms=C4orf9, NOL14; ORFNames=RES4-25;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; ISS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
//
ID   NOP16_HUMAN             Reviewed;         178 AA.
AC   Q9Y3C1; B4DV13; D6RGD3; Q05D05; Q6IAI6; Q8IXL5;
DE   RecName: Full=Nucleolar protein 16;
DE   AltName: Full=HBV pre-S2 trans-regulated protein 3;
GN   Name=NOP16; ORFNames=CGI-117, HSPC111;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NOP2_HUMAN              Reviewed;         812 AA.
AC   P46087; A1A4Z3; B3KPD6; Q05BA7; Q0P5S5; Q3KQS4; Q58F30;
DE   RecName: Full=Putative ribosomal RNA methyltransferase NOP2;
DE            EC=2.1.1.-;
DE   AltName: Full=Nucleolar protein 1;
DE   AltName: Full=Nucleolar protein 2 homolog;
DE   AltName: Full=Proliferating-cell nucleolar antigen p120;
DE   AltName: Full=Proliferation-associated nucleolar protein p120;
GN   Name=NOP2; Synonyms=NOL1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
//
ID   NOP56_HUMAN             Reviewed;         594 AA.
AC   O00567; Q2M3T6; Q9NQ05;
DE   RecName: Full=Nucleolar protein 56;
DE   AltName: Full=Nucleolar protein 5A;
GN   Name=NOP56; Synonyms=NOL5A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0030515; F:snoRNA binding; IDA:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
//
ID   NOP58_HUMAN             Reviewed;         529 AA.
AC   Q9Y2X3; Q53SA4; Q6PK08; Q9P036; Q9UFN3;
DE   RecName: Full=Nucleolar protein 58;
DE   AltName: Full=Nucleolar protein 5;
GN   Name=NOP58; Synonyms=NOL5, NOP5; ORFNames=HSPC120;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030515; F:snoRNA binding; IDA:BHF-UCL.
DR   GO; GO:0016049; P:cell growth; TAS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; TAS:UniProtKB.
DR   GO; GO:0006608; P:snRNP protein import into nucleus; ISS:UniProtKB.
//
ID   NOP9_HUMAN              Reviewed;         636 AA.
AC   Q86U38; Q8IVF0; Q8TBS6;
DE   RecName: Full=Nucleolar protein 9;
GN   Name=NOP9; Synonyms=C14orf21, KIAA2021;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NOS1_HUMAN              Reviewed;        1434 AA.
AC   P29475; E9PH30; O75713;
DE   RecName: Full=Nitric oxide synthase, brain;
DE            EC=1.14.13.39;
DE   AltName: Full=Constitutive NOS;
DE   AltName: Full=NC-NOS;
DE   AltName: Full=NOS type I;
DE   AltName: Full=Neuronal NOS;
DE            Short=N-NOS;
DE            Short=nNOS;
DE   AltName: Full=Peptidyl-cysteine S-nitrosylase NOS1;
DE   AltName: Full=bNOS;
GN   Name=NOS1;
DR   GuidetoPHARMACOLOGY; 1251; -.
DR   GO; GO:0034618; F:arginine binding; TAS:BHF-UCL.
DR   GO; GO:0046870; F:cadmium ion binding; ISS:BHF-UCL.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; ISS:BHF-UCL.
DR   GO; GO:0010181; F:FMN binding; ISS:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; ISS:BHF-UCL.
DR   GO; GO:0003958; F:NADPH-hemoprotein reductase activity; IBA:RefGenome.
DR   GO; GO:0004517; F:nitric-oxide synthase activity; ISS:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0034617; F:tetrahydrobiopterin binding; NAS:BHF-UCL.
DR   GO; GO:0006527; P:arginine catabolic process; IC:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IEA:Ensembl.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IMP:BHF-UCL.
DR   GO; GO:0007520; P:myoblast fusion; TAS:BHF-UCL.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IBA:RefGenome.
DR   GO; GO:0010523; P:negative regulation of calcium ion transport into cytosol; TAS:BHF-UCL.
DR   GO; GO:0051346; P:negative regulation of hydrolase activity; IEA:Ensembl.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0051612; P:negative regulation of serotonin uptake; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IBA:RefGenome.
DR   GO; GO:0018119; P:peptidyl-cysteine S-nitrosylation; ISS:BHF-UCL.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; IBA:RefGenome.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:1902307; P:positive regulation of sodium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IDA:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; TAS:BHF-UCL.
DR   GO; GO:0009408; P:response to heat; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEP:BHF-UCL.
DR   GO; GO:0006941; P:striated muscle contraction; IEA:Ensembl.
//
ID   NOS2_HUMAN              Reviewed;        1153 AA.
AC   P35228; A1L3U5; B7ZLY2; O60757; O94994; Q16263; Q16692; Q4TTS5;
AC   Q9UD42;
DE   RecName: Full=Nitric oxide synthase, inducible;
DE            EC=1.14.13.39;
DE   AltName: Full=Hepatocyte NOS;
DE            Short=HEP-NOS;
DE   AltName: Full=Inducible NO synthase;
DE            Short=Inducible NOS;
DE            Short=iNOS;
DE   AltName: Full=NOS type II;
DE   AltName: Full=Peptidyl-cysteine S-nitrosylase NOS2;
GN   Name=NOS2; Synonyms=NOS2A;
DR   GuidetoPHARMACOLOGY; 1250; -.
DR   GO; GO:0034618; F:arginine binding; ISS:BHF-UCL.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; ISS:BHF-UCL.
DR   GO; GO:0010181; F:FMN binding; ISS:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; ISS:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; TAS:BHF-UCL.
DR   GO; GO:0003958; F:NADPH-hemoprotein reductase activity; IBA:RefGenome.
DR   GO; GO:0004517; F:nitric-oxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0034617; F:tetrahydrobiopterin binding; ISS:BHF-UCL.
DR   GO; GO:0006527; P:arginine catabolic process; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; NAS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IBA:RefGenome.
DR   GO; GO:0002227; P:innate immune response in mucosa; NAS:BHF-UCL.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IBA:RefGenome.
DR   GO; GO:0010629; P:negative regulation of gene expression; IGI:UniProtKB.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IBA:RefGenome.
DR   GO; GO:0018119; P:peptidyl-cysteine S-nitrosylation; ISS:UniProtKB.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; IBA:RefGenome.
DR   GO; GO:0051712; P:positive regulation of killing of cells of other organism; IMP:BHF-UCL.
DR   GO; GO:0001912; P:positive regulation of leukocyte mediated cytotoxicity; TAS:BHF-UCL.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IBA:RefGenome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043457; P:regulation of cellular respiration; TAS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0009617; P:response to bacterium; NAS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
//
ID   NOS3_HUMAN              Reviewed;        1203 AA.
AC   P29474; A0S0A7; A0S0A8; A8KA63; B2RCQ1; E9PFR2; Q13662; Q14251;
AC   Q14434; Q548C1; Q6GSL5; Q9UDC6;
DE   RecName: Full=Nitric oxide synthase, endothelial;
DE            EC=1.14.13.39;
DE   AltName: Full=Constitutive NOS;
DE            Short=cNOS;
DE   AltName: Full=EC-NOS;
DE   AltName: Full=Endothelial NOS;
DE            Short=eNOS;
DE   AltName: Full=NOS type III;
DE            Short=NOSIII;
GN   Name=NOS3;
DR   GO; GO:0003785; F:actin monomer binding; IPI:BHF-UCL.
DR   GO; GO:0034618; F:arginine binding; IDA:BHF-UCL.
DR   GO; GO:0046870; F:cadmium ion binding; NAS:BHF-UCL.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; NAS:BHF-UCL.
DR   GO; GO:0010181; F:FMN binding; NAS:BHF-UCL.
DR   GO; GO:0020037; F:heme binding; IDA:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; NAS:BHF-UCL.
DR   GO; GO:0003958; F:NADPH-hemoprotein reductase activity; IBA:RefGenome.
DR   GO; GO:0004517; F:nitric-oxide synthase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034617; F:tetrahydrobiopterin binding; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006527; P:arginine catabolic process; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001974; P:blood vessel remodeling; ISS:BHF-UCL.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:BHF-UCL.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IBA:RefGenome.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; ISS:BHF-UCL.
DR   GO; GO:0051346; P:negative regulation of hydrolase activity; IEA:Ensembl.
DR   GO; GO:0014740; P:negative regulation of muscle hyperplasia; ISS:BHF-UCL.
DR   GO; GO:0010544; P:negative regulation of platelet activation; NAS:BHF-UCL.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IBA:RefGenome.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:BHF-UCL.
DR   GO; GO:0045909; P:positive regulation of vasodilation; NAS:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; NAS:BHF-UCL.
DR   GO; GO:0050880; P:regulation of blood vessel size; ISS:BHF-UCL.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0003100; P:regulation of systemic arterial blood pressure by endothelin; IMP:BHF-UCL.
DR   GO; GO:0003057; P:regulation of the force of heart contraction by chemical signal; IEA:Ensembl.
DR   GO; GO:0034405; P:response to fluid shear stress; IEP:BHF-UCL.
DR   GO; GO:0009408; P:response to heat; NAS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0014806; P:smooth muscle hyperplasia; ISS:BHF-UCL.
//
ID   NOSIP_HUMAN             Reviewed;         301 AA.
AC   Q9Y314; Q96FD2;
DE   RecName: Full=Nitric oxide synthase-interacting protein;
DE   AltName: Full=eNOS-interacting protein;
GN   Name=NOSIP; ORFNames=CGI-25;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0051001; P:negative regulation of nitric-oxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NOSTN_HUMAN             Reviewed;         506 AA.
AC   Q8IVI9; A8K2I9; B3KSF5; E7EPT9; Q27HG3; Q53S62; Q96CJ9;
DE   RecName: Full=Nostrin;
DE   AltName: Full=BM247 homolog;
DE   AltName: Full=Nitric oxide synthase traffic inducer;
DE   AltName: Full=Nitric oxide synthase trafficker;
DE   AltName: Full=eNOS-trafficking inducer;
GN   Name=NOSTRIN;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NOTC1_HUMAN             Reviewed;        2555 AA.
AC   P46531; Q59ED8; Q5SXM3;
DE   RecName: Full=Neurogenic locus notch homolog protein 1;
DE            Short=Notch 1;
DE            Short=hN1;
DE   AltName: Full=Translocation-associated notch protein TAN-1;
DE   Contains:
DE     RecName: Full=Notch 1 extracellular truncation;
DE              Short=NEXT;
DE   Contains:
DE     RecName: Full=Notch 1 intracellular domain;
DE              Short=NICD;
DE   Flags: Precursor;
GN   Name=NOTCH1; Synonyms=TAN1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR   GO; GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0003180; P:aortic valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:1902263; P:apoptotic process involved in embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0060842; P:arterial endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0003162; P:atrioventricular node development; IEA:Ensembl.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0009912; P:auditory receptor cell fate commitment; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0003209; P:cardiac atrium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003207; P:cardiac chamber formation; ISS:BHF-UCL.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003213; P:cardiac right atrium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003219; P:cardiac right ventricle formation; IEA:Ensembl.
DR   GO; GO:0060411; P:cardiac septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060948; P:cardiac vascular smooth muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0003208; P:cardiac ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0003273; P:cell migration involved in endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IDA:BHF-UCL.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072044; P:collecting duct development; IEA:Ensembl.
DR   GO; GO:0007386; P:compartment pattern specification; IEA:Ensembl.
DR   GO; GO:0060982; P:coronary artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003169; P:coronary vein morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0072017; P:distal tubule development; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060956; P:endocardial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003157; P:endocardium development; ISS:BHF-UCL.
DR   GO; GO:0003160; P:endocardium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007440; P:foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0010001; P:glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0072144; P:glomerular mesangial cell development; IEA:Ensembl.
DR   GO; GO:0003241; P:growth involved in heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IMP:DFLAT.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0061384; P:heart trabecula morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0072602; P:interleukin-4 secretion; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0070986; P:left/right axis specification; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0014031; P:mesenchymal cell development; ISS:BHF-UCL.
DR   GO; GO:0003192; P:mitral valve formation; IMP:BHF-UCL.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:BHF-UCL.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:UniProtKB.
DR   GO; GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IDA:BHF-UCL.
DR   GO; GO:2001027; P:negative regulation of endothelial cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0060253; P:negative regulation of glial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; ISS:UniProtKB.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0048715; P:negative regulation of oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030279; P:negative regulation of ossification; ISS:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0046533; P:negative regulation of photoreceptor cell differentiation; IEA:Ensembl.
DR   GO; GO:2000974; P:negative regulation of pro-B cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000737; P:negative regulation of stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEP:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; IMP:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.
DR   GO; GO:0003270; P:Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:0003344; P:pericardium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; ISS:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; ISS:UniProtKB.
DR   GO; GO:0007221; P:positive regulation of transcription of Notch receptor target; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060768; P:regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:1901201; P:regulation of extracellular matrix assembly; ISS:BHF-UCL.
DR   GO; GO:0014807; P:regulation of somitogenesis; IEA:Ensembl.
DR   GO; GO:0003256; P:regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
DR   GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0035148; P:tube formation; IMP:UniProtKB.
DR   GO; GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060843; P:venous endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; ISS:BHF-UCL.
//
ID   NOTC2_HUMAN             Reviewed;        2471 AA.
AC   Q04721; Q5T3X7; Q99734; Q9H240;
DE   RecName: Full=Neurogenic locus notch homolog protein 2;
DE            Short=Notch 2;
DE            Short=hN2;
DE   Contains:
DE     RecName: Full=Notch 2 extracellular truncation;
DE   Contains:
DE     RecName: Full=Notch 2 intracellular domain;
DE   Flags: Precursor;
GN   Name=NOTCH2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0038049; F:ligand-activated RNA polymerase II transcription factor binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0046849; P:bone remodeling; IMP:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; TAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; TAS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0072602; P:interleukin-4 secretion; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; IC:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEP:UniProtKB.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; TAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NOTC3_HUMAN             Reviewed;        2321 AA.
AC   Q9UM47; Q9UEB3; Q9UPL3; Q9Y6L8;
DE   RecName: Full=Neurogenic locus notch homolog protein 3;
DE            Short=Notch 3;
DE   Contains:
DE     RecName: Full=Notch 3 extracellular truncation;
DE   Contains:
DE     RecName: Full=Notch 3 intracellular domain;
DE   Flags: Precursor;
GN   Name=NOTCH3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0072104; P:glomerular capillary formation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NOTC4_HUMAN             Reviewed;        2003 AA.
AC   Q99466; B0V183; B0V1X5; O00306; Q5SSY7; Q99458; Q99940; Q9H3S8;
AC   Q9UII9; Q9UIJ0;
DE   RecName: Full=Neurogenic locus notch homolog protein 4;
DE            Short=Notch 4;
DE            Short=hNotch4;
DE   Contains:
DE     RecName: Full=Notch 4 extracellular truncation;
DE   Contains:
DE     RecName: Full=Notch 4 intracellular domain;
DE   Flags: Precursor;
GN   Name=NOTCH4; Synonyms=INT3;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; TAS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; TAS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; TAS:UniProtKB.
DR   GO; GO:0030879; P:mammary gland development; IDA:UniProtKB.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; ISS:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0045602; P:negative regulation of endothelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:UniProtKB.
DR   GO; GO:0007221; P:positive regulation of transcription of Notch receptor target; TAS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NOTO_HUMAN              Reviewed;         251 AA.
AC   A8MTQ0; B4DJ59; B7ZAU5;
DE   RecName: Full=Homeobox protein notochord;
GN   Name=NOTO;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NOTUM_HUMAN             Reviewed;         496 AA.
AC   Q6P988; Q8N410; Q8NI82;
DE   RecName: Full=Protein notum homolog;
DE            EC=3.-.-.-;
DE   Flags: Precursor;
GN   Name=NOTUM; ORFNames=OK/SW-CL.30;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   NOVA1_HUMAN             Reviewed;         510 AA.
AC   P51513; A8K0S4; A8K4Q7; D3DS81; D3DS82; Q6B004;
DE   RecName: Full=RNA-binding protein Nova-1;
DE   AltName: Full=Neuro-oncological ventral antigen 1;
DE   AltName: Full=Onconeural ventral antigen 1;
DE   AltName: Full=Paraneoplastic Ri antigen;
DE   AltName: Full=Ventral neuron-specific protein 1;
GN   Name=NOVA1;
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   NOVA2_HUMAN             Reviewed;         492 AA.
AC   Q9UNW9; O43267; Q9UEA1;
DE   RecName: Full=RNA-binding protein Nova-2;
DE   AltName: Full=Astrocytic NOVA1-like RNA-binding protein;
DE   AltName: Full=Neuro-oncological ventral antigen 2;
GN   Name=NOVA2; Synonyms=ANOVA, NOVA3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
//
ID   NOV_HUMAN               Reviewed;         357 AA.
AC   P48745; B2R5X7; Q6I9S3; Q96BY5; Q9UDE4;
DE   RecName: Full=Protein NOV homolog;
DE            Short=NovH;
DE   AltName: Full=CCN family member 3;
DE   AltName: Full=Insulin-like growth factor-binding protein 9;
DE            Short=IBP-9;
DE            Short=IGF-binding protein 9;
DE            Short=IGFBP-9;
DE   AltName: Full=Nephroblastoma-overexpressed gene protein homolog;
DE   Flags: Precursor;
GN   Name=NOV; Synonyms=CCN3, IGFBP9, NOVH;
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
//
ID   NOX1_HUMAN              Reviewed;         564 AA.
AC   Q9Y5S8; A8K836; O95691; Q2PP02;
DE   RecName: Full=NADPH oxidase 1;
DE            Short=NOX-1;
DE            EC=1.-.-.-;
DE   AltName: Full=Mitogenic oxidase 1;
DE            Short=MOX-1;
DE   AltName: Full=NADH/NADPH mitogenic oxidase subunit P65-MOX;
DE   AltName: Full=NOH-1;
GN   Name=NOX1; Synonyms=MOX1, NOH1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050661; F:NADP binding; IC:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0048365; F:Rac GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; TAS:UniProtKB.
DR   GO; GO:0030171; F:voltage-gated proton channel activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IMP:BHF-UCL.
DR   GO; GO:0071468; P:cellular response to acidity; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0042743; P:hydrogen peroxide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0051454; P:intracellular pH elevation; IDA:BHF-UCL.
DR   GO; GO:0006739; P:NADP metabolic process; IC:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0072592; P:oxygen metabolic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045726; P:positive regulation of integrin biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IEP:BHF-UCL.
DR   GO; GO:0015992; P:proton transport; IDA:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:BHF-UCL.
DR   GO; GO:0003081; P:regulation of systemic arterial blood pressure by renin-angiotensin; IEA:Ensembl.
DR   GO; GO:0045730; P:respiratory burst; TAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:BHF-UCL.
DR   GO; GO:0042554; P:superoxide anion generation; IDA:BHF-UCL.
DR   GO; GO:0006801; P:superoxide metabolic process; IMP:BHF-UCL.
//
ID   NOX3_HUMAN              Reviewed;         568 AA.
AC   Q9HBY0; Q9HBJ9;
DE   RecName: Full=NADPH oxidase 3;
DE            EC=1.6.3.-;
DE   AltName: Full=Mitogenic oxidase 2;
DE            Short=MOX-2;
DE   AltName: Full=gp91phox homolog 3;
DE            Short=GP91-3;
GN   Name=NOX3; Synonyms=MOX2;
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:Ensembl.
DR   GO; GO:0009590; P:detection of gravity; IEA:Ensembl.
DR   GO; GO:0048840; P:otolith development; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; IEA:Ensembl.
//
ID   NOX4_HUMAN              Reviewed;         578 AA.
AC   Q9NPH5; A8K715; B7Z520; E7EMD7; Q5K3R4; Q5K3R5; Q5K3R6; Q5K3R8;
AC   Q7Z7G3; Q86V92;
DE   RecName: Full=NADPH oxidase 4;
DE            EC=1.6.3.-;
DE   AltName: Full=Kidney oxidase-1;
DE            Short=KOX-1;
DE   AltName: Full=Kidney superoxide-producing NADPH oxidase;
DE   AltName: Full=Renal NAD(P)H-oxidase;
GN   Name=NOX4; Synonyms=RENOX;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; TAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; TAS:UniProtKB.
DR   GO; GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
DR   GO; GO:0016174; F:NAD(P)H oxidase activity; TAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; TAS:UniProtKB.
DR   GO; GO:0019826; F:oxygen sensor activity; TAS:UniProtKB.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:Ensembl.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0035051; P:cardiocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; ISS:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; ISS:UniProtKB.
//
ID   NOX5_HUMAN              Reviewed;         765 AA.
AC   Q96PH1; B2RBJ4; Q08AN2; Q08AN3; Q8TEQ1; Q8TER4; Q96PH2; Q96PJ8;
AC   Q96PJ9; Q9H6E0; Q9HAM8;
DE   RecName: Full=NADPH oxidase 5;
DE            EC=1.6.3.-;
GN   Name=NOX5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; NAS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; NAS:UniProtKB.
DR   GO; GO:0015252; F:hydrogen ion channel activity; IDA:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0050663; P:cytokine secretion; NAS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; NAS:UniProtKB.
DR   GO; GO:0001935; P:endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0015992; P:proton transport; IDA:GOC.
DR   GO; GO:0043012; P:regulation of fusion of sperm to egg plasma membrane; NAS:UniProtKB.
DR   GO; GO:0010155; P:regulation of proton transport; NAS:UniProtKB.
DR   GO; GO:0042554; P:superoxide anion generation; IDA:UniProtKB.
//
ID   NOXA1_HUMAN             Reviewed;         476 AA.
AC   Q86UR1; O60533; Q29VU9; Q29VV0; Q2TAM1; Q8IUS3;
DE   RecName: Full=NADPH oxidase activator 1;
DE            Short=NOX activator 1;
DE   AltName: Full=Antigen NY-CO-31;
DE   AltName: Full=NCF2-like protein;
DE   AltName: Full=P67phox-like factor;
DE   AltName: Full=p51-nox;
GN   Name=NOXA1; Synonyms=P51NOX;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IDA:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0010310; P:regulation of hydrogen peroxide metabolic process; IMP:BHF-UCL.
DR   GO; GO:0060263; P:regulation of respiratory burst; IMP:BHF-UCL.
DR   GO; GO:0006801; P:superoxide metabolic process; IMP:UniProtKB.
//
ID   NOXO1_HUMAN             Reviewed;         376 AA.
AC   Q8NFA2; Q86YM1; Q8NFA3; Q96B73;
DE   RecName: Full=NADPH oxidase organizer 1;
DE   AltName: Full=NADPH oxidase regulatory protein;
DE   AltName: Full=Nox organizer 1;
DE   AltName: Full=Nox-organizing protein 1;
DE   AltName: Full=SH3 and PX domain-containing protein 5;
GN   Name=NOXO1; Synonyms=P41NOX, SH3PXD5;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005543; F:phospholipid binding; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; TAS:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.
DR   GO; GO:0060263; P:regulation of respiratory burst; TAS:BHF-UCL.
DR   GO; GO:0006801; P:superoxide metabolic process; IEA:Ensembl.
//
ID   NOXIN_HUMAN             Reviewed;         998 AA.
AC   Q8IXT1; Q96LK6; Q9H856;
DE   RecName: Full=Nitric oxide-inducible gene protein;
GN   Name=NOXIN; Synonyms=C11orf82;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0071447; P:cellular response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IEA:Ensembl.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   NP10_HUMAN              Reviewed;          75 AA.
AC   P61580;
DE   RecName: Full=HERV-K_5q33.3 provirus Np9 protein;
DE   AltName: Full=HERV-K10 Np9 protein;
DE   AltName: Full=HERV-K107 Np9 protein;
//
ID   NP12_HUMAN              Reviewed;          75 AA.
AC   P61582;
DE   RecName: Full=HERV-K_1q22 provirus Np9 protein;
DE   AltName: Full=HERV-K(III) Np9 protein;
DE   AltName: Full=HERV-K102 Np9 protein;
//
ID   NP11_HUMAN              Reviewed;          75 AA.
AC   P61581;
DE   RecName: Full=HERV-K_22q11.21 provirus Np9 protein;
DE   AltName: Full=HERV-K101 Np9 protein;
//
ID   NP1L1_HUMAN             Reviewed;         391 AA.
AC   P55209; B3KNT8;
DE   RecName: Full=Nucleosome assembly protein 1-like 1;
DE   AltName: Full=NAP-1-related protein;
DE            Short=hNRP;
DE   Flags: Precursor;
GN   Name=NAP1L1; Synonyms=NRP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   NP1L2_HUMAN             Reviewed;         460 AA.
AC   Q9ULW6; B2RE61; Q8TAN6;
DE   RecName: Full=Nucleosome assembly protein 1-like 2;
DE   AltName: Full=Brain-specific protein, X-linked;
GN   Name=NAP1L2; Synonyms=BPX;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:ProtInc.
//
ID   NP1L3_HUMAN             Reviewed;         506 AA.
AC   Q99457; B2RCM0; O60788;
DE   RecName: Full=Nucleosome assembly protein 1-like 3;
GN   Name=NAP1L3; Synonyms=BNAP;
DR   GO; GO:0006334; P:nucleosome assembly; TAS:ProtInc.
//
ID   NP1L4_HUMAN             Reviewed;         375 AA.
AC   Q99733; B2R6J4; F5HFY4;
DE   RecName: Full=Nucleosome assembly protein 1-like 4;
DE   AltName: Full=Nucleosome assembly protein 2;
DE            Short=NAP-2;
GN   Name=NAP1L4; Synonyms=NAP2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:ProtInc.
//
ID   NP1L5_HUMAN             Reviewed;         182 AA.
AC   Q96NT1;
DE   RecName: Full=Nucleosome assembly protein 1-like 5;
DE   AltName: Full=Down-regulated in liver malignancy;
GN   Name=NAP1L5; Synonyms=DRLM;
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   NP1L6_HUMAN             Reviewed;         107 AA.
AC   A6NFF2;
DE   RecName: Full=Putative nucleosome assembly protein 1-like 6;
GN   Name=NAP1L6;
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   NP8_HUMAN               Reviewed;          75 AA.
AC   P61583;
DE   RecName: Full=HERV-K_3q12.3 provirus Np9 protein;
DE   AltName: Full=Endogenous retrovirus K protein 5;
DE   AltName: Full=HERV-K(II) Np9 protein;
GN   Name=ERVK-5; Synonyms=ERVK5;
//
ID   NPA1P_HUMAN             Reviewed;        2271 AA.
AC   O60287; D3DSE5; Q96NX1; Q9NYQ1;
DE   RecName: Full=Nucleolar pre-ribosomal-associated protein 1;
DE   AltName: Full=Nucleolar protein 254 kDa;
DE   AltName: Full=URB1 ribosome biogenesis 1 homolog;
GN   Name=URB1; Synonyms=C21orf108, KIAA0539, NOP254, NPA1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NPAL2_HUMAN             Reviewed;         368 AA.
AC   Q9H841;
DE   RecName: Full=NIPA-like protein 2;
GN   Name=NIPAL2; Synonyms=NPAL2;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
//
ID   NPAL3_HUMAN             Reviewed;         406 AA.
AC   Q6P499; A2A298; Q6MZT9; Q9BVE6;
DE   RecName: Full=NIPA-like protein 3;
GN   Name=NIPAL3; Synonyms=NPAL3;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
//
ID   NPAP1_HUMAN             Reviewed;        1156 AA.
AC   Q9NZP6;
DE   RecName: Full=Nuclear pore-associated protein 1;
GN   Name=NPAP1; Synonyms=C15orf2;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   NPAS1_HUMAN             Reviewed;         590 AA.
AC   Q99742; B4DR69; Q99632; Q9BY83;
DE   RecName: Full=Neuronal PAS domain-containing protein 1;
DE            Short=Neuronal PAS1;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP5;
DE   AltName: Full=Class E basic helix-loop-helix protein 11;
DE            Short=bHLHe11;
DE   AltName: Full=Member of PAS protein 5;
DE   AltName: Full=PAS domain-containing protein 5;
GN   Name=NPAS1; Synonyms=BHLHE11, MOP5, PASD5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NPAS2_HUMAN             Reviewed;         824 AA.
AC   Q99743; Q4ZFV9; Q53SQ3; Q86V96; Q99629;
DE   RecName: Full=Neuronal PAS domain-containing protein 2;
DE            Short=Neuronal PAS2;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP4;
DE   AltName: Full=Class E basic helix-loop-helix protein 9;
DE            Short=bHLHe9;
DE   AltName: Full=Member of PAS protein 4;
DE   AltName: Full=PAS domain-containing protein 4;
GN   Name=NPAS2; Synonyms=BHLHE9, MOP4, PASD4;
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0042745; P:circadian sleep/wake cycle; IEA:Ensembl.
DR   GO; GO:0045475; P:locomotor rhythm; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:2001020; P:regulation of response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0051775; P:response to redox state; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NPAS3_HUMAN             Reviewed;         933 AA.
AC   Q8IXF0; Q86US6; Q86US7; Q8IXF2; Q9BY81; Q9H323; Q9Y4L8;
DE   RecName: Full=Neuronal PAS domain-containing protein 3;
DE            Short=Neuronal PAS3;
DE   AltName: Full=Basic-helix-loop-helix-PAS protein MOP6;
DE   AltName: Full=Class E basic helix-loop-helix protein 12;
DE            Short=bHLHe12;
DE   AltName: Full=Member of PAS protein 6;
DE   AltName: Full=PAS domain-containing protein 6;
GN   Name=NPAS3; Synonyms=BHLHE12, MOP6, PASD6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NPAS4_HUMAN             Reviewed;         802 AA.
AC   Q8IUM7; Q8N8S5; Q8N9Q9;
DE   RecName: Full=Neuronal PAS domain-containing protein 4;
DE            Short=Neuronal PAS4;
DE   AltName: Full=Class E basic helix-loop-helix protein 79;
DE            Short=bHLHe79;
DE   AltName: Full=HLH-PAS transcription factor NXF;
DE   AltName: Full=PAS domain-containing protein 10;
GN   Name=NPAS4; Synonyms=BHLHE79, NXF, PASD10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NPAT_HUMAN              Reviewed;        1427 AA.
AC   Q14207; A8K1V5; A8K6M2; Q13632; Q14967; Q16580; Q86W55; Q8IWE9;
DE   RecName: Full=Protein NPAT;
DE   AltName: Full=Nuclear protein of the ataxia telangiectasia mutated locus;
DE            Short=Nuclear protein of the ATM locus;
DE   AltName: Full=p220;
GN   Name=NPAT; Synonyms=CAND3, E14;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NPB15_HUMAN             Reviewed;         443 AA.
AC   A6NHN6; C9J9U8;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B15;
DE   AltName: Full=Nuclear pore complex-interacting protein-like 2;
DE   Flags: Precursor;
GN   Name=NPIPB15; Synonyms=NPIPL2;
//
ID   NPB11_HUMAN             Reviewed;        1161 AA.
AC   E5RHQ5;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B11;
GN   Name=NPIPB11;
//
ID   NPBW1_HUMAN             Reviewed;         328 AA.
AC   P48145; Q6NTC7;
DE   RecName: Full=Neuropeptides B/W receptor type 1;
DE   AltName: Full=G-protein coupled receptor 7;
GN   Name=NPBWR1; Synonyms=GPR7;
DR   GuidetoPHARMACOLOGY; 303; -.
DR   GO; GO:0008188; F:neuropeptide receptor activity; IEA:InterPro.
DR   GO; GO:0004985; F:opioid receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; TAS:GOC.
DR   GO; GO:0019222; P:regulation of metabolic process; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   NPBW2_HUMAN             Reviewed;         333 AA.
AC   P48146; Q6NWQ6; Q9H4K3;
DE   RecName: Full=Neuropeptides B/W receptor type 2;
DE   AltName: Full=G-protein coupled receptor 8;
GN   Name=NPBWR2; Synonyms=GPR8;
DR   GuidetoPHARMACOLOGY; 304; -.
DR   GO; GO:0008188; F:neuropeptide receptor activity; IEA:InterPro.
DR   GO; GO:0004985; F:opioid receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; TAS:GOC.
//
ID   NPB_HUMAN               Reviewed;         125 AA.
AC   Q8NG41; A0AUX9; A6NJD6; B9EJC3;
DE   RecName: Full=Neuropeptide B;
DE   AltName: Full=Preproprotein L7;
DE            Short=hPPL7;
DE   Contains:
DE     RecName: Full=Neuropeptide B-23;
DE              Short=NPB23;
DE              Short=hL7;
DE   Contains:
DE     RecName: Full=Neuropeptide B-29;
DE              Short=NPB29;
DE              Short=hL7C;
DE   Flags: Precursor;
GN   Name=NPB; Synonyms=PPL7, PPNPB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
//
ID   NPC1_HUMAN              Reviewed;        1278 AA.
AC   O15118; Q9P130;
DE   RecName: Full=Niemann-Pick C1 protein;
DE   Flags: Precursor;
GN   Name=NPC1;
DR   GO; GO:0015485; F:cholesterol binding; IDA:UniProtKB.
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0015248; F:sterol transporter activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0006914; P:autophagy; IGI:MGI.
DR   GO; GO:0008206; P:bile acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0071404; P:cellular response to low-density lipoprotein particle stimulus; IEA:Ensembl.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030301; P:cholesterol transport; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0007041; P:lysosomal transport; ISS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0016242; P:negative regulation of macroautophagy; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; IDA:UniProtKB.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   NPC2_HUMAN              Reviewed;         151 AA.
AC   P61916; Q15668; Q29413;
DE   RecName: Full=Epididymal secretory protein E1;
DE   AltName: Full=Human epididymis-specific protein 1;
DE            Short=He1;
DE   AltName: Full=Niemann-Pick disease type C2 protein;
DE   Flags: Precursor;
GN   Name=NPC2; Synonyms=HE1;
DR   GO; GO:0015485; F:cholesterol binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030301; P:cholesterol transport; IDA:UniProtKB.
DR   GO; GO:0046836; P:glycolipid transport; TAS:HGNC.
DR   GO; GO:0032367; P:intracellular cholesterol transport; IDA:UniProtKB.
DR   GO; GO:0032366; P:intracellular sterol transport; IDA:HGNC.
DR   GO; GO:0015914; P:phospholipid transport; TAS:HGNC.
DR   GO; GO:0019747; P:regulation of isoprenoid metabolic process; TAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   NPCL1_HUMAN             Reviewed;        1359 AA.
AC   Q9UHC9; A4D2J7; B7ZLE6; D3DVK9; Q17RV5; Q6R3Q4; Q9UHC8;
DE   RecName: Full=Niemann-Pick C1-like protein 1;
DE   Flags: Precursor;
GN   Name=NPC1L1;
DR   GuidetoPHARMACOLOGY; 2629; -.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0031489; F:myosin V binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IMP:HGNC.
DR   GO; GO:0030301; P:cholesterol transport; IMP:HGNC.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; IMP:HGNC.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IMP:HGNC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0015918; P:sterol transport; TAS:Reactome.
//
ID   NPCR1_HUMAN             Reviewed;         106 AA.
AC   Q9BY65; Q8NG33;
DE   RecName: Full=Nasopharyngeal carcinoma down-regulated gene protein 1;
DE            Short=NPCDRG;
DE   AltName: Full=Nasopharyngeal carcinoma-related gene protein;
GN   Name=NPCDR1; Synonyms=NPCR;
//
ID   NPDC1_HUMAN             Reviewed;         325 AA.
AC   Q9NQX5; Q5SPY8; Q9BTD6; Q9BXT3; Q9NQS2; Q9Y434;
DE   RecName: Full=Neural proliferation differentiation and control protein 1;
DE            Short=NPDC-1;
DE   Flags: Precursor;
GN   Name=NPDC1;
//
ID   NPFF1_HUMAN             Reviewed;         430 AA.
AC   Q9GZQ6; A2RRF0; Q8NGR0; Q96RN3;
DE   RecName: Full=Neuropeptide FF receptor 1;
DE   AltName: Full=G-protein coupled receptor 147;
DE   AltName: Full=RFamide-related peptide receptor OT7T022;
GN   Name=NPFFR1; Synonyms=GPR147, NPFF1;
DR   GuidetoPHARMACOLOGY; 300; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0008188; F:neuropeptide receptor activity; NAS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:GOC.
//
ID   NPFF2_HUMAN             Reviewed;         522 AA.
AC   Q9Y5X5; Q96RV1; Q9NR49;
DE   RecName: Full=Neuropeptide FF receptor 2;
DE   AltName: Full=G-protein coupled receptor 74;
DE   AltName: Full=G-protein coupled receptor HLWAR77;
DE   AltName: Full=Neuropeptide G-protein coupled receptor;
GN   Name=NPFFR2; Synonyms=GPR74, NPFF2, NPGPR;
DR   GuidetoPHARMACOLOGY; 301; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008188; F:neuropeptide receptor activity; IEA:InterPro.
DR   GO; GO:0009582; P:detection of abiotic stimulus; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045761; P:regulation of adenylate cyclase activity; IEA:InterPro.
DR   GO; GO:2000479; P:regulation of cAMP-dependent protein kinase activity; IEA:InterPro.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:InterPro.
//
ID   NPFF_HUMAN              Reviewed;         113 AA.
AC   O15130;
DE   RecName: Full=Pro-FMRFamide-related neuropeptide FF;
DE   AltName: Full=FMRFamide-related peptides;
DE   Contains:
DE     RecName: Full=Neuropeptide SF;
DE              Short=NPSF;
DE   Contains:
DE     RecName: Full=Neuropeptide FF;
DE              Short=NPFF;
DE   Contains:
DE     RecName: Full=Neuropeptide AF;
DE              Short=NPAF;
DE   Flags: Precursor;
GN   Name=NPFF;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0002438; P:acute inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0032099; P:negative regulation of appetite; IEA:Ensembl.
DR   GO; GO:0010459; P:negative regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0003254; P:regulation of membrane depolarization; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0070253; P:somatostatin secretion; IEA:Ensembl.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0030103; P:vasopressin secretion; IEA:Ensembl.
//
ID   NPHN_HUMAN              Reviewed;        1241 AA.
AC   O60500; A6NDH2; C3RX61;
DE   RecName: Full=Nephrin;
DE   AltName: Full=Renal glomerulus-specific cell adhesion receptor;
DE   Flags: Precursor;
GN   Name=NPHS1; Synonyms=NPHN;
DR   GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0032836; P:glomerular basement membrane development; IEP:UniProtKB.
DR   GO; GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0044062; P:regulation of excretion; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
//
ID   NPHP1_HUMAN             Reviewed;         732 AA.
AC   O15259; O14837;
DE   RecName: Full=Nephrocystin-1;
DE   AltName: Full=Juvenile nephronophthisis 1 protein;
GN   Name=NPHP1; Synonyms=NPH1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0035845; P:photoreceptor cell outer segment organization; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0048515; P:spermatid differentiation; ISS:UniProtKB.
DR   GO; GO:0007632; P:visual behavior; NAS:UniProtKB.
//
ID   NPHP3_HUMAN             Reviewed;        1330 AA.
AC   Q7Z494; Q5JPE3; Q5JPE6; Q68D99; Q6NVH3; Q7Z492; Q7Z493; Q8N9R2;
AC   Q8NCM5; Q96N70; Q96NK2;
DE   RecName: Full=Nephrocystin-3;
GN   Name=NPHP3; Synonyms=KIAA2000;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003283; P:atrial septum development; IMP:BHF-UCL.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060027; P:convergent extension involved in gastrulation; IGI:BHF-UCL.
DR   GO; GO:0071908; P:determination of intestine left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; IMP:BHF-UCL.
DR   GO; GO:0071910; P:determination of liver left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0035469; P:determination of pancreatic left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0071909; P:determination of stomach left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IC:BHF-UCL.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:0060993; P:kidney morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IMP:BHF-UCL.
DR   GO; GO:0048496; P:maintenance of organ identity; IMP:HGNC.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0030814; P:regulation of cAMP metabolic process; IEA:Ensembl.
DR   GO; GO:2000167; P:regulation of planar cell polarity pathway involved in neural tube closure; IC:BHF-UCL.
DR   GO; GO:2000095; P:regulation of Wnt signaling pathway, planar cell polarity pathway; ISS:UniProtKB.
DR   GO; GO:0072189; P:ureter development; IMP:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NPHP4_HUMAN             Reviewed;        1426 AA.
AC   O75161; Q8IWC0;
DE   RecName: Full=Nephrocystin-4;
DE   AltName: Full=Nephroretinin;
GN   Name=NPHP4; Synonyms=KIAA0673;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007632; P:visual behavior; NAS:UniProtKB.
//
ID   NPIA7_HUMAN             Reviewed;         369 AA.
AC   E9PJI5;
DE   RecName: Full=Nuclear pore complex-interacting protein family member A7;
GN   Name=NPIPA7;
//
ID   NPIA8_HUMAN             Reviewed;         369 AA.
AC   P0DM63;
DE   RecName: Full=Nuclear pore complex-interacting protein family member A8;
GN   Name=NPIPA8;
//
ID   NPIB3_HUMAN             Reviewed;        1050 AA.
AC   Q92617; O43332; Q504Q6; Q59F29; Q6GMR1; Q6P7T2; Q6PIE2; Q6RH21;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B3;
DE   AltName: Full=Nuclear pore complex-interacting protein-like 3;
DE   AltName: Full=Protein pps22-1;
GN   Name=NPIPB3; Synonyms=KIAA0220, NPIPL3;
//
ID   NPIA5_HUMAN             Reviewed;         350 AA.
AC   E9PKD4;
DE   RecName: Full=Nuclear pore complex-interacting protein family member A5;
GN   Name=NPIPA5;
//
ID   NPIA2_HUMAN             Reviewed;         369 AA.
AC   E9PIF3;
DE   RecName: Full=Nuclear pore complex-interacting protein family member A2;
GN   Name=NPIPA2;
//
ID   NPIB5_HUMAN             Reviewed;        1133 AA.
AC   A8MRT5; B4DK13;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B5;
GN   Name=NPIPB5;
//
ID   NPIB4_HUMAN             Reviewed;        1138 AA.
AC   C9JG80;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B4;
GN   Name=NPIPB4;
//
ID   NPIB7_HUMAN             Reviewed;         414 AA.
AC   O75200; E7ERT9;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B7;
DE   AltName: Full=Nuclear pore complex-interacting protein-like 1;
DE   Flags: Precursor;
GN   Name=NPIPB7; Synonyms=NPIPL1;
//
ID   NPIB6_HUMAN             Reviewed;         425 AA.
AC   E9PJ23;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B6;
GN   Name=NPIPB6;
//
ID   NPIB9_HUMAN             Reviewed;         429 AA.
AC   F8W1W9;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B9;
GN   Name=NPIPB9;
//
ID   NPIA3_HUMAN             Reviewed;         350 AA.
AC   F8WFD2;
DE   RecName: Full=Nuclear pore complex-interacting protein family member A3;
GN   Name=NPIPA3;
//
ID   NPIA1_HUMAN             Reviewed;         350 AA.
AC   Q9UND3; O15102;
DE   RecName: Full=Nuclear pore complex-interacting protein family member A1;
DE   AltName: Full=Nuclear pore complex-interacting protein;
DE            Short=NPIP;
GN   Name=NPIPA1; Synonyms=NPIP;
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NPIB8_HUMAN             Reviewed;         432 AA.
AC   E9PQR5;
DE   RecName: Full=Nuclear pore complex-interacting protein family member B8;
GN   Name=NPIPB8;
//
ID   NPIL2_HUMAN             Reviewed;         397 AA.
AC   A6NJ64; J3KPX4;
DE   RecName: Full=Putative NPIP-like protein LOC729978;
//
ID   NPIL5_HUMAN             Reviewed;        1138 AA.
AC   A6NJU9;
DE   RecName: Full=Putative NPIP-like protein LOC613037;
//
ID   NPL4_HUMAN              Reviewed;         608 AA.
AC   Q8TAT6; Q8N3J1; Q9H8V2; Q9H964; Q9NWR5; Q9P229;
DE   RecName: Full=Nuclear protein localization protein 4 homolog;
DE            Short=Protein NPL4;
GN   Name=NPLOC4; Synonyms=KIAA1499, NPL4;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; ISS:HGNC.
DR   GO; GO:0007030; P:Golgi organization; ISS:HGNC.
DR   GO; GO:0061025; P:membrane fusion; ISS:HGNC.
//
ID   NPL_HUMAN               Reviewed;         320 AA.
AC   Q9BXD5; B2R839; Q4G0Q8; Q4G0Z2; Q64L88; Q6PEL0;
DE   RecName: Full=N-acetylneuraminate lyase;
DE            Short=NALase;
DE            EC=4.1.3.3;
DE   AltName: Full=N-acetylneuraminate pyruvate-lyase;
DE   AltName: Full=N-acetylneuraminic acid aldolase;
DE   AltName: Full=Sialate lyase;
DE   AltName: Full=Sialate-pyruvate lyase;
DE   AltName: Full=Sialic acid aldolase;
DE   AltName: Full=Sialic acid lyase;
GN   Name=NPL; Synonyms=C1orf13;
DR   GO; GO:0008747; F:N-acetylneuraminate lyase activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0019262; P:N-acetylneuraminate catabolic process; TAS:UniProtKB.
//
ID   NPM2_HUMAN              Reviewed;         214 AA.
AC   Q86SE8; B3KSU0; D3DSQ8; Q6NVH6;
DE   RecName: Full=Nucleoplasmin-2;
GN   Name=NPM2;
DR   GO; GO:0042393; F:histone binding; TAS:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IMP:UniProtKB.
DR   GO; GO:0009994; P:oocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0045836; P:positive regulation of meiosis; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0007096; P:regulation of exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; IMP:UniProtKB.
//
ID   NPM3_HUMAN              Reviewed;         178 AA.
AC   O75607; Q9UNY6;
DE   RecName: Full=Nucleoplasmin-3;
GN   Name=NPM3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006364; P:rRNA processing; IEA:Ensembl.
DR   GO; GO:0009303; P:rRNA transcription; IEA:Ensembl.
//
ID   NPM_HUMAN               Reviewed;         294 AA.
AC   P06748; A8K3N7; B5BU00; D3DQL6; P08693; Q12826; Q13440; Q13441;
AC   Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962;
AC   Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7;
DE   RecName: Full=Nucleophosmin;
DE            Short=NPM;
DE   AltName: Full=Nucleolar phosphoprotein B23;
DE   AltName: Full=Nucleolar protein NO38;
DE   AltName: Full=Numatrin;
GN   Name=NPM1; Synonyms=NPM;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IMP:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IDA:MGI.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IDA:MGI.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0030957; F:Tat protein binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0007569; P:cell aging; IMP:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0007098; P:centrosome cycle; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010826; P:negative regulation of centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0044387; P:negative regulation of protein kinase activity by regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:MGI.
DR   GO; GO:0046599; P:regulation of centriole replication; IMP:UniProtKB.
DR   GO; GO:0060735; P:regulation of eIF2 alpha phosphorylation by dsRNA; IDA:UniProtKB.
DR   GO; GO:0032071; P:regulation of endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0060699; P:regulation of endoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IMP:UniProtKB.
DR   GO; GO:0042255; P:ribosome assembly; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NPNT_HUMAN              Reviewed;         565 AA.
AC   Q6UXI9; A6NFT9; A8K1W4; B4DIT4; B4DYK3; B4E2H7; B4E3H2; D6RCA1;
AC   E9PCK8; E9PCQ1; E9PE64; E9PF04;
DE   RecName: Full=Nephronectin;
DE   AltName: Full=Preosteoblast EGF-like repeat protein with MAM domain;
DE   AltName: Full=Protein EGFL6-like;
DE   Flags: Precursor;
GN   Name=NPNT; Synonyms=EGFL6L, POEM; ORFNames=UNQ295/PRO334;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; ISS:BHF-UCL.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0033631; P:cell-cell adhesion mediated by integrin; ISS:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; ISS:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:BHF-UCL.
DR   GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; ISS:BHF-UCL.
DR   GO; GO:0097195; P:pilomotor reflex; IEA:Ensembl.
DR   GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:2000721; P:positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; ISS:BHF-UCL.
//
ID   NPRL2_HUMAN             Reviewed;         380 AA.
AC   Q8WTW4; A8K831; Q6FGS2; Q9Y249; Q9Y497;
DE   RecName: Full=Nitrogen permease regulator 2-like protein;
DE            Short=NPR2-like protein;
DE   AltName: Full=Gene 21 protein;
DE            Short=G21 protein;
DE   AltName: Full=Tumor suppressor candidate 4;
GN   Name=NPRL2; Synonyms=TUSC4;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
//
ID   NPRL3_HUMAN             Reviewed;         569 AA.
AC   Q12980; D3DU40; Q1W6H0; Q4TT56; Q92469;
DE   RecName: Full=Nitrogen permease regulator 3-like protein;
DE   AltName: Full=-14 gene protein;
DE   AltName: Full=Alpha-globin regulatory element-containing gene protein;
DE   AltName: Full=Protein CGTHBA;
GN   Name=NPRL3; Synonyms=C16orf35, CGTHBA, MARE;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   NPS3A_HUMAN             Reviewed;         247 AA.
AC   Q9UFN0; A6NM55; Q5VX32; Q9BRV7; Q9H843; Q9P083;
DE   RecName: Full=Protein NipSnap homolog 3A;
DE            Short=NipSnap3A;
DE   AltName: Full=Protein NipSnap homolog 4;
DE            Short=NipSnap4;
DE   AltName: Full=Target for Salmonella secreted protein C;
DE            Short=TassC;
GN   Name=NIPSNAP3A; Synonyms=NIPSNAP4; ORFNames=HSPC299;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NPS3B_HUMAN             Reviewed;         247 AA.
AC   Q9BS92; Q5VX30; Q9NUM2;
DE   RecName: Full=Protein NipSnap homolog 3B;
DE            Short=NipSnap3B;
DE   AltName: Full=SNAP1;
GN   Name=NIPSNAP3B; Synonyms=NIPSNAP3;
//
ID   NPSR1_HUMAN             Reviewed;         371 AA.
AC   Q6W5P4; A2RTZ4; Q2XP58; Q56H76; Q56H77; Q56H78; Q6JSL4; Q6JSL5;
AC   Q6JSL6; Q6JSL7; Q6JSL8; Q6W5P3; Q6ZMB8;
DE   RecName: Full=Neuropeptide S receptor;
DE   AltName: Full=G-protein coupled receptor 154;
DE   AltName: Full=G-protein coupled receptor PGR14;
DE   AltName: Full=G-protein coupled receptor for asthma susceptibility;
GN   Name=NPSR1; Synonyms=GPR154, GPRA, PGR14;
DR   GuidetoPHARMACOLOGY; 302; -.
DR   GO; GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
//
ID   NPS_HUMAN               Reviewed;          89 AA.
AC   P0C0P6;
DE   RecName: Full=Neuropeptide S;
DE   Flags: Precursor;
GN   Name=NPS;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045760; P:positive regulation of action potential; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   NPT1_HUMAN              Reviewed;         467 AA.
AC   Q14916; A8K418; O60761; Q13783; Q3MIP5; Q5MJP8; Q5TB83; Q96KL8;
DE   RecName: Full=Sodium-dependent phosphate transport protein 1;
DE   AltName: Full=Na(+)/PI cotransporter 1;
DE   AltName: Full=Na/Pi-4;
DE   AltName: Full=Renal Na(+)-dependent phosphate cotransporter 1;
DE   AltName: Full=Renal sodium-dependent phosphate transport protein 1;
DE            Short=Renal sodium-phosphate transport protein 1;
DE   AltName: Full=Sodium/phosphate cotransporter 1;
DE   AltName: Full=Solute carrier family 17 member 1;
GN   Name=SLC17A1; Synonyms=NPT1;
DR   GO; GO:0015321; F:sodium-dependent phosphate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006817; P:phosphate ion transport; TAS:ProtInc.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0044341; P:sodium-dependent phosphate transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046415; P:urate metabolic process; IMP:BHF-UCL.
//
ID   NPT2A_HUMAN             Reviewed;         639 AA.
AC   Q06495; B4DPE3;
DE   RecName: Full=Sodium-dependent phosphate transport protein 2A;
DE            Short=Sodium-phosphate transport protein 2A;
DE   AltName: Full=Na(+)-dependent phosphate cotransporter 2A;
DE   AltName: Full=NaPi-3;
DE   AltName: Full=Sodium/phosphate cotransporter 2A;
DE            Short=Na(+)/Pi cotransporter 2A;
DE            Short=NaPi-2a;
DE   AltName: Full=Solute carrier family 34 member 1;
GN   Name=SLC34A1; Synonyms=NPT2, SLC17A2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015321; F:sodium-dependent phosphate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:1901684; P:arsenate ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0071248; P:cellular response to metal ion; IEA:Ensembl.
DR   GO; GO:0071374; P:cellular response to parathyroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0072734; P:cellular response to staurosporine; IEA:Ensembl.
DR   GO; GO:0097187; P:dentinogenesis; IEA:Ensembl.
DR   GO; GO:1901128; P:gentamycin metabolic process; IEA:Ensembl.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0042431; P:indole metabolic process; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0055062; P:phosphate ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006817; P:phosphate ion transport; IDA:UniProtKB.
DR   GO; GO:0045838; P:positive regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:2000187; P:positive regulation of phosphate transmembrane transport; IEA:Ensembl.
DR   GO; GO:2000120; P:positive regulation of sodium-dependent phosphate transport; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0060416; P:response to growth hormone; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IDA:UniProtKB.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0046689; P:response to mercury ion; IDA:UniProtKB.
DR   GO; GO:0035864; P:response to potassium ion; IEA:Ensembl.
DR   GO; GO:0097066; P:response to thyroid hormone; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0072350; P:tricarboxylic acid metabolic process; IEA:Ensembl.
//
ID   NPT2B_HUMAN             Reviewed;         690 AA.
AC   O95436; A5PL17; Q8N2K2; Q8WYA9; Q9P0V7;
DE   RecName: Full=Sodium-dependent phosphate transport protein 2B;
DE            Short=Sodium-phosphate transport protein 2B;
DE   AltName: Full=Na(+)-dependent phosphate cotransporter 2B;
DE   AltName: Full=NaPi3b;
DE   AltName: Full=Sodium/phosphate cotransporter 2B;
DE            Short=Na(+)/Pi cotransporter 2B;
DE            Short=NaPi-2b;
DE   AltName: Full=Solute carrier family 34 member 2;
GN   Name=SLC34A2;
DR   GO; GO:0042301; F:phosphate ion binding; IDA:UniProtKB.
DR   GO; GO:0031402; F:sodium ion binding; IDA:UniProtKB.
DR   GO; GO:0015321; F:sodium-dependent phosphate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006817; P:phosphate ion transport; IDA:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEP:UniProtKB.
DR   GO; GO:0009750; P:response to fructose; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NPT2C_HUMAN             Reviewed;         599 AA.
AC   Q8N130; A2BFA1;
DE   RecName: Full=Sodium-dependent phosphate transport protein 2C;
DE            Short=Sodium-phosphate transport protein 2C;
DE   AltName: Full=Na(+)-dependent phosphate cotransporter 2C;
DE   AltName: Full=Sodium/inorganic phosphate cotransporter IIC;
DE   AltName: Full=Sodium/phosphate cotransporter 2C;
DE            Short=Na(+)/Pi cotransporter 2C;
DE            Short=NaPi-2c;
DE   AltName: Full=Solute carrier family 34 member 3;
GN   Name=SLC34A3; Synonyms=NPT2C, NPTIIC;
DR   GO; GO:0015321; F:sodium-dependent phosphate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; IDA:UniProtKB.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006817; P:phosphate ion transport; IDA:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006814; P:sodium ion transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   NPT3_HUMAN              Reviewed;         439 AA.
AC   O00624; A6NK81; A6NLD6; Q5TB84; Q76P85;
DE   RecName: Full=Sodium-dependent phosphate transport protein 3;
DE   AltName: Full=Na(+)/PI cotransporter 3;
DE   AltName: Full=Sodium/phosphate cotransporter 3;
DE   AltName: Full=Solute carrier family 17 member 2;
GN   Name=SLC17A2; Synonyms=NPT3;
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; TAS:ProtInc.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   NPT4_HUMAN              Reviewed;         420 AA.
AC   O00476; B7WNJ5; B7Z511; Q8WWC7; Q9H533;
DE   RecName: Full=Sodium-dependent phosphate transport protein 4;
DE   AltName: Full=Na(+)/PI cotransporter 4;
DE   AltName: Full=Sodium/phosphate cotransporter 4;
DE   AltName: Full=Solute carrier family 17 member 3;
GN   Name=SLC17A3; Synonyms=NPT4;
DR   GO; GO:0015238; F:drug transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; ISS:UniProtKB.
DR   GO; GO:0019534; F:toxin transporter activity; IDA:UniProtKB.
DR   GO; GO:0015143; F:urate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0008308; F:voltage-gated anion channel activity; IDA:UniProtKB.
DR   GO; GO:0006855; P:drug transmembrane transport; IDA:GOC.
DR   GO; GO:0015893; P:drug transport; IDA:UniProtKB.
DR   GO; GO:0015760; P:glucose-6-phosphate transport; TAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0015849; P:organic acid transport; IDA:GOC.
DR   GO; GO:0015711; P:organic anion transport; IDA:UniProtKB.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; ISS:GOC.
DR   GO; GO:0006817; P:phosphate ion transport; ISS:UniProtKB.
DR   GO; GO:0044070; P:regulation of anion transport; IDA:GOC.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; ISS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; ISS:UniProtKB.
DR   GO; GO:1901998; P:toxin transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046415; P:urate metabolic process; IMP:UniProtKB.
DR   GO; GO:0015747; P:urate transport; IDA:UniProtKB.
//
ID   NPTN_HUMAN              Reviewed;         398 AA.
AC   Q9Y639; B2RAL7; B7Z4D3; B7ZLL2; Q17R52; Q59EJ9; Q6NVX7; Q9Y640;
DE   RecName: Full=Neuroplastin;
DE   AltName: Full=Stromal cell-derived receptor 1;
DE            Short=SDR-1;
DE   Flags: Precursor;
GN   Name=NPTN; Synonyms=SDFR1, SDR1;
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:HGNC.
DR   GO; GO:0005105; F:type 1 fibroblast growth factor receptor binding; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:HGNC.
DR   GO; GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:UniProtKB.
DR   GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; ISS:HGNC.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
//
ID   NPTX1_HUMAN             Reviewed;         432 AA.
AC   Q15818; B3KXH3; Q5FWE6;
DE   RecName: Full=Neuronal pentraxin-1;
DE            Short=NP1;
DE   AltName: Full=Neuronal pentraxin I;
DE            Short=NP-I;
DE   Flags: Precursor;
GN   Name=NPTX1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0060385; P:axonogenesis involved in innervation; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0035865; P:cellular response to potassium ion; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0043653; P:mitochondrial fragmentation involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   NPTX2_HUMAN             Reviewed;         431 AA.
AC   P47972; A4D267; Q86XV7; Q96G70;
DE   RecName: Full=Neuronal pentraxin-2;
DE            Short=NP2;
DE   AltName: Full=Neuronal pentraxin II;
DE            Short=NP-II;
DE   Flags: Precursor;
GN   Name=NPTX2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
//
ID   NPTXR_HUMAN             Reviewed;         500 AA.
AC   O95502;
DE   RecName: Full=Neuronal pentraxin receptor;
GN   Name=NPTXR;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NPVF_HUMAN              Reviewed;         196 AA.
AC   Q9HCQ7; A4D164; Q7LE27; Q96PI9;
DE   RecName: Full=Pro-FMRFamide-related neuropeptide VF;
DE   Contains:
DE     RecName: Full=Neuropeptide NPSF;
DE   Contains:
DE     RecName: Full=Neuropeptide RFRP-1;
DE   Contains:
DE     RecName: Full=Neuropeptide RFRP-2;
DE   Contains:
DE     RecName: Full=Neuropeptide NPVF;
DE     AltName: Full=Neuropeptide RFRP-3;
DE   Flags: Precursor;
GN   Name=NPVF; Synonyms=C7orf9, RFRP;
DR   GO; GO:0032277; P:negative regulation of gonadotropin secretion; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   NPW_HUMAN               Reviewed;         165 AA.
AC   Q8N729;
DE   RecName: Full=Neuropeptide W;
DE   AltName: Full=Preproprotein L8;
DE            Short=hPPL8;
DE   Contains:
DE     RecName: Full=Neuropeptide W-23;
DE              Short=NPW23;
DE              Short=hL8;
DE   Contains:
DE     RecName: Full=Neuropeptide W-30;
DE              Short=NPW30;
DE              Short=hL8C;
DE   Flags: Precursor;
GN   Name=NPW; Synonyms=PPL8, PPNPW;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0007631; P:feeding behavior; IDA:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
//
ID   NPY1R_HUMAN             Reviewed;         384 AA.
AC   P25929; B2R6H5;
DE   RecName: Full=Neuropeptide Y receptor type 1;
DE            Short=NPY1-R;
GN   Name=NPY1R; Synonyms=NPYR, NPYY1;
DR   GuidetoPHARMACOLOGY; 305; -.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; TAS:ProtInc.
DR   GO; GO:0001602; F:pancreatic polypeptide receptor activity; IEA:Ensembl.
DR   GO; GO:0001601; F:peptide YY receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:GOC.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
//
ID   NPY2R_HUMAN             Reviewed;         381 AA.
AC   P49146; Q13281; Q13457; Q4W5G7; Q6AZZ6; Q9UE67;
DE   RecName: Full=Neuropeptide Y receptor type 2;
DE            Short=NPY2-R;
DE   AltName: Full=NPY-Y2 receptor;
DE            Short=Y2 receptor;
GN   Name=NPY2R;
DR   GuidetoPHARMACOLOGY; 306; -.
DR   GO; GO:0005246; F:calcium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; TAS:ProtInc.
DR   GO; GO:0001601; F:peptide YY receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; TAS:ProtInc.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0031645; P:negative regulation of neurological system process; IEA:Ensembl.
DR   GO; GO:0051048; P:negative regulation of secretion; IEA:Ensembl.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:GOC.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0046010; P:positive regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0033603; P:positive regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0002793; P:positive regulation of peptide secretion; IEA:Ensembl.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0046903; P:secretion; IEA:Ensembl.
//
ID   NPY4R_HUMAN             Reviewed;         375 AA.
AC   P50391; Q13456; Q5ISU3; Q5T2X9; Q6FH06;
DE   RecName: Full=Neuropeptide Y receptor type 4;
DE            Short=NPY4-R;
DE   AltName: Full=Pancreatic polypeptide receptor 1;
DE            Short=PP1;
GN   Name=NPY4R; Synonyms=PPYR1;
DR   GuidetoPHARMACOLOGY; 307; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0001602; F:pancreatic polypeptide receptor activity; IEA:Ensembl.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0001601; F:peptide YY receptor activity; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   NPY5R_HUMAN             Reviewed;         445 AA.
AC   Q15761; Q6GTR7; Q92916;
DE   RecName: Full=Neuropeptide Y receptor type 5;
DE            Short=NPY5-R;
DE   AltName: Full=NPY-Y5 receptor;
DE            Short=NPYY5-R;
DE            Short=Y5 receptor;
GN   Name=NPY5R; Synonyms=NPYR5;
DR   GuidetoPHARMACOLOGY; 308; -.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; TAS:ProtInc.
DR   GO; GO:0001602; F:pancreatic polypeptide receptor activity; IEA:Ensembl.
DR   GO; GO:0001601; F:peptide YY receptor activity; IEA:Ensembl.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0060112; P:generation of ovulation cycle rhythm; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:GOC.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
//
ID   NPY6R_HUMAN             Reviewed;         290 AA.
AC   Q99463; D3DQB4;
DE   RecName: Full=Putative neuropeptide Y receptor type 6;
DE            Short=NPY6-R;
DE   AltName: Full=NPY Y1-like receptor;
DE   AltName: Full=Putative pancreatic polypeptide receptor 2;
DE            Short=PP2;
GN   Name=NPY6R; Synonyms=NPY1RL, Y2B;
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
//
ID   NPY_HUMAN               Reviewed;          97 AA.
AC   P01303;
DE   RecName: Full=Pro-neuropeptide Y;
DE   Contains:
DE     RecName: Full=Neuropeptide Y;
DE     AltName: Full=Neuropeptide tyrosine;
DE              Short=NPY;
DE   Contains:
DE     RecName: Full=C-flanking peptide of NPY;
DE              Short=CPON;
DE   Flags: Precursor;
GN   Name=NPY;
DR   GO; GO:0005246; F:calcium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008343; P:adult feeding behavior; ISS:HGNC.
DR   GO; GO:0007610; P:behavior; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; NAS:ProtInc.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0021954; P:central nervous system neuron development; IEP:DFLAT.
DR   GO; GO:0021987; P:cerebral cortex development; IEP:DFLAT.
DR   GO; GO:0007586; P:digestion; NAS:ProtInc.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0031175; P:neuron projection development; IEP:DFLAT.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0032100; P:positive regulation of appetite; ISS:HGNC.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   NQO1_HUMAN              Reviewed;         274 AA.
AC   P15559; B2R5Y9; B4DNM7; B7ZAD1; Q86UK1;
DE   RecName: Full=NAD(P)H dehydrogenase [quinone] 1;
DE            EC=1.6.5.2;
DE   AltName: Full=Azoreductase;
DE   AltName: Full=DT-diaphorase;
DE            Short=DTD;
DE   AltName: Full=Menadione reductase;
DE   AltName: Full=NAD(P)H:quinone oxidoreductase 1;
DE   AltName: Full=Phylloquinone reductase;
DE   AltName: Full=Quinone reductase 1;
DE            Short=QR1;
GN   Name=NQO1; Synonyms=DIA4, NMOR1;
DR   GO; GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; TAS:ProtInc.
DR   GO; GO:0003955; F:NAD(P)H dehydrogenase (quinone) activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006801; P:superoxide metabolic process; IEA:Ensembl.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; TAS:ProtInc.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:ProtInc.
//
ID   NQO2_HUMAN              Reviewed;         231 AA.
AC   P16083; B2R492; Q5TD04;
DE   RecName: Full=Ribosyldihydronicotinamide dehydrogenase [quinone];
DE            EC=1.10.99.2;
DE   AltName: Full=NRH dehydrogenase [quinone] 2;
DE   AltName: Full=NRH:quinone oxidoreductase 2;
DE   AltName: Full=Quinone reductase 2;
DE            Short=QR2;
GN   Name=NQO2; Synonyms=NMOR2;
DR   GO; GO:0001512; F:dihydronicotinamide riboside quinone reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008753; F:NADPH dehydrogenase (quinone) activity; TAS:ProtInc.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
//
ID   NR0B1_HUMAN             Reviewed;         470 AA.
AC   P51843; Q96F69;
DE   RecName: Full=Nuclear receptor subfamily 0 group B member 1;
DE   AltName: Full=DSS-AHC critical region on the X chromosome protein 1;
DE   AltName: Full=Nuclear receptor DAX-1;
GN   Name=NR0B1; Synonyms=AHC, DAX1;
DR   GO; GO:0050682; F:AF-2 domain binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:HGNC.
DR   GO; GO:0032448; F:DNA hairpin binding; IDA:HGNC.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:HGNC.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:HGNC.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0035258; F:steroid hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030325; P:adrenal gland development; IMP:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008406; P:gonad development; IMP:HGNC.
DR   GO; GO:0021854; P:hypothalamus development; NAS:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IMP:UniProtKB.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0033144; P:negative regulation of intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0021983; P:pituitary gland development; NAS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
DR   GO; GO:0035902; P:response to immobilization stress; IEA:Ensembl.
DR   GO; GO:0060008; P:Sertoli cell differentiation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006694; P:steroid biosynthetic process; IDA:HGNC.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR0B2_HUMAN             Reviewed;         257 AA.
AC   Q15466; F1D8P5; Q5QP36;
DE   RecName: Full=Nuclear receptor subfamily 0 group B member 2;
DE   AltName: Full=Orphan nuclear receptor SHP;
DE   AltName: Full=Small heterodimer partner;
GN   Name=NR0B2; Synonyms=SHP;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR1D1_HUMAN             Reviewed;         614 AA.
AC   P20393; Q0P5Z4; Q15304;
DE   RecName: Full=Nuclear receptor subfamily 1 group D member 1;
DE   AltName: Full=Rev-erbA-alpha;
DE   AltName: Full=V-erbA-related protein 1;
DE            Short=EAR-1;
GN   Name=NR1D1; Synonyms=EAR1, HREV, THRAL;
DR   GuidetoPHARMACOLOGY; 596; -.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0001222; F:transcription corepressor binding; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0060086; P:circadian temperature homeostasis; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0010871; P:negative regulation of receptor biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0070859; P:positive regulation of bile acid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0010498; P:proteasomal protein catabolic process; ISS:UniProtKB.
DR   GO; GO:2000188; P:regulation of cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0035947; P:regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.
DR   GO; GO:0061469; P:regulation of type B pancreatic cell proliferation; ISS:UniProtKB.
DR   GO; GO:0044321; P:response to leptin; ISS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR1D2_HUMAN             Reviewed;         579 AA.
AC   Q14995; B2R8Q3; O00402; Q86XD4;
DE   RecName: Full=Nuclear receptor subfamily 1 group D member 2;
DE   AltName: Full=Orphan nuclear hormone receptor BD73;
DE   AltName: Full=Rev-erb alpha-related receptor;
DE            Short=RVR;
DE   AltName: Full=Rev-erb-beta;
DE   AltName: Full=V-erbA-related protein 1-related;
DE            Short=EAR-1R;
GN   Name=NR1D2;
DR   GuidetoPHARMACOLOGY; 597; -.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0055088; P:lipid homeostasis; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.
DR   GO; GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR1H2_HUMAN             Reviewed;         460 AA.
AC   P55055; A8K490; B4DNM6; E7EWA6; Q12970; Q5I0Y1;
DE   RecName: Full=Oxysterols receptor LXR-beta;
DE   AltName: Full=Liver X receptor beta;
DE   AltName: Full=Nuclear receptor NER;
DE   AltName: Full=Nuclear receptor subfamily 1 group H member 2;
DE   AltName: Full=Ubiquitously-expressed nuclear receptor;
GN   Name=NR1H2; Synonyms=LXRB, NER, UNR;
DR   GuidetoPHARMACOLOGY; 601; -.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0010887; P:negative regulation of cholesterol storage; IMP:BHF-UCL.
DR   GO; GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0032369; P:negative regulation of lipid transport; IMP:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0048550; P:negative regulation of pinocytosis; IMP:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.
DR   GO; GO:0032376; P:positive regulation of cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0090108; P:positive regulation of high-density lipoprotein particle assembly; IEA:Ensembl.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IEA:Ensembl.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IMP:BHF-UCL.
DR   GO; GO:0090187; P:positive regulation of pancreatic juice secretion; IEA:Ensembl.
DR   GO; GO:0090340; P:positive regulation of secretion of lysosomal enzymes; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:2000188; P:regulation of cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR1H3_HUMAN             Reviewed;         447 AA.
AC   Q13133; A8K3J9; D3DQR1; Q8IW13; Q96H87;
DE   RecName: Full=Oxysterols receptor LXR-alpha;
DE   AltName: Full=Liver X receptor alpha;
DE   AltName: Full=Nuclear receptor subfamily 1 group H member 3;
GN   Name=NR1H3; Synonyms=LXRA;
DR   GuidetoPHARMACOLOGY; 602; -.
DR   GO; GO:0015485; F:cholesterol binding; TAS:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0032810; F:sterol response element binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043277; P:apoptotic cell clearance; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0010887; P:negative regulation of cholesterol storage; IMP:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0032369; P:negative regulation of lipid transport; IMP:BHF-UCL.
DR   GO; GO:0043031; P:negative regulation of macrophage activation; ISS:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0090188; P:negative regulation of pancreatic juice secretion; ISS:BHF-UCL.
DR   GO; GO:0048550; P:negative regulation of pinocytosis; IMP:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0090341; P:negative regulation of secretion of lysosomal enzymes; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:2000189; P:positive regulation of cholesterol homeostasis; IDA:BHF-UCL.
DR   GO; GO:0032376; P:positive regulation of cholesterol transport; IDA:BHF-UCL.
DR   GO; GO:0045723; P:positive regulation of fatty acid biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0051006; P:positive regulation of lipoprotein lipase activity; IMP:BHF-UCL.
DR   GO; GO:0010870; P:positive regulation of receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:2000188; P:regulation of cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; TAS:BHF-UCL.
DR   GO; GO:0032570; P:response to progesterone; IDA:BHF-UCL.
DR   GO; GO:0055092; P:sterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; ISS:BHF-UCL.
//
ID   NR1I2_HUMAN             Reviewed;         434 AA.
AC   O75469; Q006P5; Q008C8; Q96AC7; Q9UJ22; Q9UJ23; Q9UJ24; Q9UJ25;
AC   Q9UJ26; Q9UJ27; Q9UNW4;
DE   RecName: Full=Nuclear receptor subfamily 1 group I member 2;
DE   AltName: Full=Orphan nuclear receptor PAR1;
DE   AltName: Full=Orphan nuclear receptor PXR;
DE   AltName: Full=Pregnane X receptor;
DE   AltName: Full=Steroid and xenobiotic receptor;
DE            Short=SXR;
GN   Name=NR1I2; Synonyms=PXR;
DR   GuidetoPHARMACOLOGY; 606; -.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046618; P:drug export; IDA:UniProtKB.
DR   GO; GO:0042738; P:exogenous drug catabolic process; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
DR   GO; GO:0042908; P:xenobiotic transport; IDA:UniProtKB.
//
ID   NR1H4_HUMAN             Reviewed;         486 AA.
AC   Q96RI1; A1L4K5; B7Z412; B7ZM06; F8VYG8; Q8NFP5; Q8NFP6; Q92943;
DE   RecName: Full=Bile acid receptor;
DE   AltName: Full=Farnesoid X-activated receptor;
DE   AltName: Full=Farnesol receptor HRR-1;
DE   AltName: Full=Nuclear receptor subfamily 1 group H member 4;
DE   AltName: Full=Retinoid X receptor-interacting protein 14;
DE            Short=RXR-interacting protein 14;
GN   Name=NR1H4; Synonyms=BAR, FXR, HRR1, RIP14;
DR   GuidetoPHARMACOLOGY; 603; -.
DR   GO; GO:0032052; F:bile acid binding; ISS:BHF-UCL.
DR   GO; GO:0038181; F:bile acid receptor activity; IDA:UniProtKB.
DR   GO; GO:1902122; F:chenodeoxycholic acid binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; TAS:BHF-UCL.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:Ensembl.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008206; P:bile acid metabolic process; IEA:Ensembl.
DR   GO; GO:0071229; P:cellular response to acid; IDA:BHF-UCL.
DR   GO; GO:0071417; P:cellular response to organonitrogen compound; ISS:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0038185; P:intracellular bile acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0070858; P:negative regulation of bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0001080; P:nitrogen catabolite activation of transcription from RNA polymerase II promoter; IC:BHF-UCL.
DR   GO; GO:2001250; P:positive regulation of ammonia assimilation cycle; IEA:Ensembl.
DR   GO; GO:2000213; P:positive regulation of glutamate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0070857; P:regulation of bile acid biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0006109; P:regulation of carbohydrate metabolic process; IEA:Ensembl.
DR   GO; GO:0090181; P:regulation of cholesterol metabolic process; TAS:BHF-UCL.
DR   GO; GO:0034255; P:regulation of urea metabolic process; ISS:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR1I3_HUMAN             Reviewed;         352 AA.
AC   Q14994; E9PGH6; E9PH10; E9PHN4; F1D8Q0; F1D8Q1; Q0VAC9; Q4U0F0;
AC   Q5VTW5; Q5VTW6; Q6GZ68; Q6GZ77; Q6GZ78; Q6GZ83; Q6GZ84; Q6GZ85;
AC   Q6GZ87;
DE   RecName: Full=Nuclear receptor subfamily 1 group I member 3;
DE   AltName: Full=Constitutive activator of retinoid response;
DE            Short=Constitutive active response;
DE   AltName: Full=Constitutive androstane receptor;
DE            Short=CAR;
DE   AltName: Full=Orphan nuclear receptor MB67;
GN   Name=NR1I3; Synonyms=CAR;
DR   GuidetoPHARMACOLOGY; 607; -.
DR   GO; GO:0004882; F:androgen receptor activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; TAS:GOC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR2C1_HUMAN             Reviewed;         603 AA.
AC   P13056; A8K5K4; Q15625; Q15626;
DE   RecName: Full=Nuclear receptor subfamily 2 group C member 1;
DE   AltName: Full=Orphan nuclear receptor TR2;
DE   AltName: Full=Testicular receptor 2;
GN   Name=NR2C1; Synonyms=TR2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048386; P:positive regulation of retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR2C2_HUMAN             Reviewed;         596 AA.
AC   P49116; A8K3H5; B6ZGT8; P55092;
DE   RecName: Full=Nuclear receptor subfamily 2 group C member 2;
DE   AltName: Full=Orphan nuclear receptor TAK1;
DE   AltName: Full=Orphan nuclear receptor TR4;
DE   AltName: Full=Testicular receptor 4;
GN   Name=NR2C2; Synonyms=TAK1, TR4;
DR   GuidetoPHARMACOLOGY; 614; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048520; P:positive regulation of behavior; IEA:Ensembl.
DR   GO; GO:0040019; P:positive regulation of embryonic development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR2CA_HUMAN             Reviewed;         139 AA.
AC   Q86WQ0; A6NGP7;
DE   RecName: Full=Nuclear receptor 2C2-associated protein;
DE   AltName: Full=TR4 orphan receptor-associated 16 kDa protein;
GN   Name=NR2C2AP; Synonyms=TRA16;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR2E1_HUMAN             Reviewed;         385 AA.
AC   Q9Y466; Q6ZMP8;
DE   RecName: Full=Nuclear receptor subfamily 2 group E member 1;
DE   AltName: Full=Nuclear receptor TLX;
DE   AltName: Full=Protein tailless homolog;
DE            Short=Tll;
DE            Short=hTll;
GN   Name=NR2E1; Synonyms=TLX;
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002118; P:aggressive behavior; IEA:Ensembl.
DR   GO; GO:0021764; P:amygdala development; IEA:Ensembl.
DR   GO; GO:0021960; P:anterior commissure morphogenesis; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0021872; P:forebrain generation of neurons; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR   GO; GO:0021819; P:layer formation in cerebral cortex; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:2000178; P:negative regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0090049; P:regulation of cell migration involved in sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0060164; P:regulation of timing of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   NR2E3_HUMAN             Reviewed;         410 AA.
AC   Q9Y5X4; B6ZGU0; Q9UHM4;
DE   RecName: Full=Photoreceptor-specific nuclear receptor;
DE   AltName: Full=Nuclear receptor subfamily 2 group E member 3;
DE   AltName: Full=Retina-specific nuclear receptor;
GN   Name=NR2E3; Synonyms=PNR, RNR;
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0007602; P:phototransduction; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   NR2F6_HUMAN             Reviewed;         404 AA.
AC   P10588; B2RC68; Q5XGA0; Q6P586; Q9BUE8;
DE   RecName: Full=Nuclear receptor subfamily 2 group F member 6;
DE   AltName: Full=V-erbA-related protein 2;
DE            Short=EAR-2;
GN   Name=NR2F6; Synonyms=EAR2, ERBAL2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0043153; P:entrainment of circadian clock by photoperiod; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR3L1_HUMAN             Reviewed;         454 AA.
AC   Q68D85; Q7Z3M6;
DE   RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1;
DE   AltName: Full=B7 homolog 6;
DE            Short=B7-H6;
DE   Flags: Precursor;
GN   Name=NCR3LG1; Synonyms=B7H6;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   NR4A1_HUMAN             Reviewed;         598 AA.
AC   P22736; B4DML7; Q15627; Q53Y00; Q6IBU8;
DE   RecName: Full=Nuclear receptor subfamily 4 group A member 1;
DE   AltName: Full=Early response protein NAK1;
DE   AltName: Full=Nuclear hormone receptor NUR/77;
DE            Short=Nur77;
DE   AltName: Full=Orphan nuclear receptor HMR;
DE   AltName: Full=Orphan nuclear receptor TR3;
DE   AltName: Full=ST-59;
DE   AltName: Full=Testicular receptor 3;
GN   Name=NR4A1; Synonyms=GFRP1, HMR, NAK1;
DR   GO; GO:0003677; F:DNA binding; ISS:BHF-UCL.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NR4A2_HUMAN             Reviewed;         598 AA.
AC   P43354; Q16311; Q53RZ2;
DE   RecName: Full=Nuclear receptor subfamily 4 group A member 2;
DE   AltName: Full=Immediate-early response protein NOT;
DE   AltName: Full=Orphan nuclear receptor NURR1;
DE   AltName: Full=Transcriptionally-inducible nuclear receptor;
GN   Name=NR4A2; Synonyms=NOT, NURR1, TINUR;
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IDA:MGI.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0016265; P:death; IEA:Ensembl.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0051866; P:general adaptation syndrome; IEA:Ensembl.
DR   GO; GO:0021986; P:habenula development; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0043576; P:regulation of respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010035; P:response to inorganic substance; IEA:Ensembl.
DR   GO; GO:0017085; P:response to insecticide; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   NR4A3_HUMAN             Reviewed;         626 AA.
AC   Q92570; A2A3I7; Q12935; Q14979; Q16420; Q4VXA8; Q4VXA9; Q9UEK2;
AC   Q9UEK3;
DE   RecName: Full=Nuclear receptor subfamily 4 group A member 3;
DE   AltName: Full=Mitogen-induced nuclear orphan receptor;
DE   AltName: Full=Neuron-derived orphan receptor 1;
DE   AltName: Full=Nuclear hormone receptor NOR-1;
GN   Name=NR4A3; Synonyms=CHN, CSMF, MINOR, NOR1, TEC;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:2000108; P:positive regulation of leukocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0060005; P:vestibular reflex; IEA:Ensembl.
//
ID   NR5A2_HUMAN             Reviewed;         541 AA.
AC   O00482; B4E2P3; O95642; Q147U3;
DE   RecName: Full=Nuclear receptor subfamily 5 group A member 2;
DE   AltName: Full=Alpha-1-fetoprotein transcription factor;
DE   AltName: Full=B1-binding factor;
DE            Short=hB1F;
DE   AltName: Full=CYP7A promoter-binding factor;
DE   AltName: Full=Hepatocytic transcription factor;
DE   AltName: Full=Liver receptor homolog 1;
DE            Short=LRH-1;
GN   Name=NR5A2; Synonyms=B1F, CPF, FTF;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008206; P:bile acid metabolic process; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; TAS:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NR6A1_HUMAN             Reviewed;         480 AA.
AC   Q15406; O00551; O00603; Q5T6F4; Q8NHQ0; Q92898; Q99802;
DE   RecName: Full=Nuclear receptor subfamily 6 group A member 1;
DE   AltName: Full=Germ cell nuclear factor;
DE            Short=GCNF;
DE            Short=hGCNF;
DE   AltName: Full=Retinoid receptor-related testis-specific receptor;
DE            Short=RTR;
DE            Short=hRTR;
GN   Name=NR6A1; Synonyms=GCNF;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007276; P:gamete generation; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NRAC_HUMAN              Reviewed;         160 AA.
AC   Q8N912;
DE   RecName: Full=Nutritionally-regulated adipose and cardiac enriched protein homolog;
GN   Name=NRAC; Synonyms=C14orf180, C14orf77;
//
ID   NRAM1_HUMAN             Reviewed;         550 AA.
AC   P49279; C0H5Y3;
DE   RecName: Full=Natural resistance-associated macrophage protein 1;
DE            Short=NRAMP 1;
DE   AltName: Full=Solute carrier family 11 member 1;
GN   Name=SLC11A1; Synonyms=LSH, NRAMP, NRAMP1;
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0051139; F:metal ion:proton antiporter activity; IGI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0046915; F:transition metal ion transmembrane transporter activity; IGI:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0048002; P:antigen processing and presentation of peptide antigen; ISS:BHF-UCL.
DR   GO; GO:0070574; P:cadmium ion transmembrane transport; IGI:BHF-UCL.
DR   GO; GO:0006876; P:cellular cadmium ion homeostasis; IGI:BHF-UCL.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:BHF-UCL.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; ISS:BHF-UCL.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:BHF-UCL.
DR   GO; GO:0070839; P:divalent metal ion export; ISS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0032623; P:interleukin-2 production; ISS:BHF-UCL.
DR   GO; GO:0032632; P:interleukin-3 production; ISS:BHF-UCL.
DR   GO; GO:0055072; P:iron ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006826; P:iron ion transport; IMP:BHF-UCL.
DR   GO; GO:0043091; P:L-arginine import; ISS:BHF-UCL.
DR   GO; GO:0042116; P:macrophage activation; ISS:BHF-UCL.
DR   GO; GO:0006828; P:manganese ion transport; ISS:BHF-UCL.
DR   GO; GO:0045342; P:MHC class II biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0048255; P:mRNA stabilization; ISS:BHF-UCL.
DR   GO; GO:0060586; P:multicellular organismal iron ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0001818; P:negative regulation of cytokine production; ISS:BHF-UCL.
DR   GO; GO:0015707; P:nitrite transport; ISS:BHF-UCL.
DR   GO; GO:0006909; P:phagocytosis; ISS:BHF-UCL.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0001819; P:positive regulation of cytokine production; ISS:BHF-UCL.
DR   GO; GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; ISS:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; ISS:BHF-UCL.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0045730; P:respiratory burst; ISS:BHF-UCL.
DR   GO; GO:0009617; P:response to bacterium; IDA:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; ISS:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0002369; P:T cell cytokine production; ISS:BHF-UCL.
DR   GO; GO:0002309; P:T cell proliferation involved in immune response; ISS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007035; P:vacuolar acidification; ISS:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; ISS:BHF-UCL.
//
ID   NRAM2_HUMAN             Reviewed;         568 AA.
AC   P49281; B3KT08; B4DK84; F5H741; O43288; O60932; O94801; Q498Z5;
AC   Q8IUD7; Q96J35;
DE   RecName: Full=Natural resistance-associated macrophage protein 2;
DE            Short=NRAMP 2;
DE   AltName: Full=Divalent cation transporter 1;
DE   AltName: Full=Divalent metal transporter 1;
DE            Short=DMT-1;
DE   AltName: Full=Solute carrier family 11 member 2;
GN   Name=SLC11A2; Synonyms=DCT1, DMT1, NRAMP2; ORFNames=OK/SW-cl.20;
DR   GO; GO:0046870; F:cadmium ion binding; IEA:Ensembl.
DR   GO; GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:Ensembl.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR   GO; GO:0005375; F:copper ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0022890; F:inorganic cation transmembrane transporter activity; IGI:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:Ensembl.
DR   GO; GO:0015094; F:lead ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0030145; F:manganese ion binding; IEA:Ensembl.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0016151; F:nickel cation binding; IEA:Ensembl.
DR   GO; GO:0015099; F:nickel cation transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015295; F:solute:proton symporter activity; IDA:UniProtKB.
DR   GO; GO:0015100; F:vanadium ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0070574; P:cadmium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071281; P:cellular response to iron ion; IEA:Ensembl.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0006824; P:cobalt ion transport; IDA:UniProtKB.
DR   GO; GO:0006825; P:copper ion transport; IDA:BHF-UCL.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0003032; P:detection of oxygen; IEP:UniProtKB.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0070627; P:ferrous iron import; IDA:UniProtKB.
DR   GO; GO:0015684; P:ferrous iron transport; IDA:BHF-UCL.
DR   GO; GO:0006783; P:heme biosynthetic process; IEA:Ensembl.
DR   GO; GO:0015692; P:lead ion transport; IDA:BHF-UCL.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0071421; P:manganese ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006828; P:manganese ion transport; IDA:BHF-UCL.
DR   GO; GO:0060586; P:multicellular organismal iron ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0035444; P:nickel cation transmembrane transport; IDA:GOC.
DR   GO; GO:0015675; P:nickel cation transport; IDA:UniProtKB.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0010039; P:response to iron ion; IEP:UniProtKB.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015676; P:vanadium ion transport; IDA:GOC.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IDA:GOC.
//
ID   NRAP_HUMAN              Reviewed;        1730 AA.
AC   Q86VF7; O15500; Q5VWI3; Q5VWI4; Q6MZK3; Q6N026; Q6N059; Q6NSH8;
AC   Q6PDB0; Q719H6; Q86TC5; Q86TD6; Q86TE6; Q86VF6; Q8N3R6; Q8N8F9;
AC   Q8TCH0; Q96MG4;
DE   RecName: Full=Nebulin-related-anchoring protein;
DE            Short=N-RAP;
GN   Name=NRAP;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0051371; F:muscle alpha-actinin binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   NRARP_HUMAN             Reviewed;         114 AA.
AC   Q7Z6K4; B8A4K5;
DE   RecName: Full=Notch-regulated ankyrin repeat-containing protein;
GN   Name=NRARP;
DR   GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IBA:RefGenome.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IMP:MGI.
DR   GO; GO:1902367; P:negative regulation of Notch signaling pathway involved in somitogenesis; IEA:Ensembl.
DR   GO; GO:0045581; P:negative regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IBA:RefGenome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:MGI.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IBA:RefGenome.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
//
ID   NRBF2_HUMAN             Reviewed;         287 AA.
AC   Q96F24; A6PW36; B4DWS0; Q86UR2; Q96NP6; Q9H0S9; Q9H2I2;
DE   RecName: Full=Nuclear receptor-binding factor 2;
DE            Short=NRBF-2;
DE   AltName: Full=Comodulator of PPAR and RXR;
GN   Name=NRBF2; Synonyms=COPR;
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NRBP2_HUMAN             Reviewed;         501 AA.
AC   Q9NSY0; B4DF59; Q2HIX8; Q597G7; Q8NCX8; Q8WYS5;
DE   RecName: Full=Nuclear receptor-binding protein 2;
DE   AltName: Full=Transformation-related gene 16 protein;
DE            Short=TRG-16;
GN   Name=NRBP2; ORFNames=PP9320, TRG16;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0016242; P:negative regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
//
ID   NRBP_HUMAN              Reviewed;         535 AA.
AC   Q9UHY1; B3KV40; D6W558; Q53FZ5; Q96SU3;
DE   RecName: Full=Nuclear receptor-binding protein;
GN   Name=NRBP1; Synonyms=BCON3, NRBP;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   NRCAM_HUMAN             Reviewed;        1304 AA.
AC   Q92823; A4D0S3; E9PDA4; O15051; O15179; Q14BM2; Q9UHI3; Q9UHI4;
DE   RecName: Full=Neuronal cell adhesion molecule;
DE            Short=Nr-CAM;
DE   AltName: Full=Neuronal surface protein Bravo;
DE            Short=hBravo;
DE   AltName: Full=NgCAM-related cell adhesion molecule;
DE            Short=Ng-CAM-related;
DE   Flags: Precursor;
GN   Name=NRCAM; Synonyms=KIAA0343;
DR   GO; GO:0030506; F:ankyrin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007413; P:axonal fasciculation; NAS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; IDA:UniProtKB.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; NAS:UniProtKB.
DR   GO; GO:0019227; P:neuronal action potential propagation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; NAS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0030516; P:regulation of axon extension; NAS:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
//
ID   NRDC_HUMAN              Reviewed;        1150 AA.
AC   O43847; A6NI41; O15241; O15242; Q5VUL0; Q96HB2; Q9NU57;
DE   RecName: Full=Nardilysin;
DE            EC=3.4.24.61;
DE   AltName: Full=N-arginine dibasic convertase;
DE            Short=NRD convertase;
DE            Short=NRD-C;
DE   Flags: Precursor;
GN   Name=NRD1;
DR   GO; GO:0048408; F:epidermal growth factor binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; TAS:ProtInc.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0052548; P:regulation of endopeptidase activity; IDA:BHF-UCL.
//
ID   NRDE2_HUMAN             Reviewed;        1164 AA.
AC   Q9H7Z3; B4DH71; Q4G0A7; Q9NWH6;
DE   RecName: Full=Protein NRDE2 homolog;
GN   Name=NRDE2; Synonyms=C14orf102;
//
ID   NREP_HUMAN              Reviewed;          68 AA.
AC   Q16612; B2RDN8; B7Z5D2; D3DSZ8;
DE   RecName: Full=Neuronal regeneration-related protein;
DE   AltName: Full=Neuronal protein 3.1;
DE   AltName: Full=Protein p311;
GN   Name=NREP; Synonyms=C5orf13, P311;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031103; P:axon regeneration; IEA:Ensembl.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   NRF1_HUMAN              Reviewed;         503 AA.
AC   Q16656; A8K4C6; B4DDV6; Q15305; Q96AN2;
DE   RecName: Full=Nuclear respiratory factor 1;
DE            Short=NRF-1;
DE   AltName: Full=Alpha palindromic-binding protein;
DE            Short=Alpha-pal;
GN   Name=NRF1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NRG1_HUMAN              Reviewed;         640 AA.
AC   Q02297; A5YAK4; A5YAK5; A8K1L2; B7Z4Z3; E9PHH4; O14667; P98202;
AC   Q02298; Q02299; Q07110; Q07111; Q12779; Q12780; Q12781; Q12782;
AC   Q12783; Q12784; Q15491; Q7RTV9; Q7RTW0; Q7RTW1; Q7RTW2; Q8NFN1;
AC   Q8NFN2; Q8NFN3; Q9UPE3;
DE   RecName: Full=Pro-neuregulin-1, membrane-bound isoform;
DE            Short=Pro-NRG1;
DE   Contains:
DE     RecName: Full=Neuregulin-1;
DE     AltName: Full=Acetylcholine receptor-inducing activity;
DE              Short=ARIA;
DE     AltName: Full=Breast cancer cell differentiation factor p45;
DE     AltName: Full=Glial growth factor;
DE     AltName: Full=Heregulin;
DE              Short=HRG;
DE     AltName: Full=Neu differentiation factor;
DE     AltName: Full=Sensory and motor neuron-derived factor;
DE   Flags: Precursor;
GN   Name=NRG1; Synonyms=GGF, HGL, HRGA, NDF, SMDF;
DR   GO; GO:0005125; F:cytokine activity; TAS:BHF-UCL.
DR   GO; GO:0043125; F:ErbB-3 class receptor binding; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; NAS:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:MGI.
DR   GO; GO:0030297; F:transmembrane receptor protein tyrosine kinase activator activity; IC:BHF-UCL.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0003161; P:cardiac conduction system development; IEA:Ensembl.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060379; P:cardiac muscle cell myoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0007154; P:cell communication; TAS:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0043624; P:cellular protein complex disassembly; IGI:MGI.
DR   GO; GO:0009790; P:embryo development; IEA:InterPro.
DR   GO; GO:0060956; P:endocardial cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038127; P:ERBB signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0021781; P:glial cell fate commitment; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; TAS:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:BHF-UCL.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0051048; P:negative regulation of secretion; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0007399; P:nervous system development; TAS:BHF-UCL.
DR   GO; GO:0014032; P:neural crest cell development; TAS:BHF-UCL.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0045213; P:neurotransmitter receptor metabolic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0051155; P:positive regulation of striated muscle cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; TAS:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; IDA:BHF-UCL.
//
ID   NRG2_HUMAN              Reviewed;         850 AA.
AC   O14511;
DE   RecName: Full=Pro-neuregulin-2, membrane-bound isoform;
DE            Short=Pro-NRG2;
DE   Contains:
DE     RecName: Full=Neuregulin-2;
DE              Short=NRG-2;
DE     AltName: Full=Divergent of neuregulin-1;
DE              Short=DON-1;
DE     AltName: Full=Neural- and thymus-derived activator for ERBB kinases;
DE              Short=NTAK;
DE   Flags: Precursor;
GN   Name=NRG2; Synonyms=NTAK;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; IEA:InterPro.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   NRG3_HUMAN              Reviewed;         720 AA.
AC   P56975; A4D7U1; Q0PEH2; Q5VYH3;
DE   RecName: Full=Pro-neuregulin-3, membrane-bound isoform;
DE            Short=Pro-NRG3;
DE   Contains:
DE     RecName: Full=Neuregulin-3;
DE              Short=NRG-3;
DE   Flags: Precursor;
GN   Name=NRG3;
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; NAS:UniProtKB.
DR   GO; GO:0030297; F:transmembrane receptor protein tyrosine kinase activator activity; NAS:UniProtKB.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; NAS:GOC.
DR   GO; GO:0060596; P:mammary placode formation; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   NRG4_HUMAN              Reviewed;         115 AA.
AC   Q8WWG1; A6NIE8;
DE   RecName: Full=Pro-neuregulin-4, membrane-bound isoform;
DE            Short=Pro-NRG4;
DE   Contains:
DE     RecName: Full=Neuregulin-4;
DE              Short=NRG-4;
GN   Name=NRG4;
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
//
ID   NRIP1_HUMAN             Reviewed;        1158 AA.
AC   P48552; Q8IWE8;
DE   RecName: Full=Nuclear receptor-interacting protein 1;
DE   AltName: Full=Nuclear factor RIP140;
DE   AltName: Full=Receptor-interacting protein 140;
GN   Name=NRIP1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.
DR   GO; GO:0035259; F:glucocorticoid receptor binding; IPI:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0001543; P:ovarian follicle rupture; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NRIP2_HUMAN             Reviewed;         281 AA.
AC   Q9BQI9; A2RRE3; B4DV61;
DE   RecName: Full=Nuclear receptor-interacting protein 2;
GN   Name=NRIP2;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NRIP3_HUMAN             Reviewed;         241 AA.
AC   Q9NQ35; Q86WD9;
DE   RecName: Full=Nuclear receptor-interacting protein 3;
DE   AltName: Full=Sarcoma antigen NY-SAR-105;
GN   Name=NRIP3; Synonyms=C11orf14;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
//
ID   NRK1_HUMAN              Reviewed;         199 AA.
AC   Q9NWW6; Q5W124; Q8N430;
DE   RecName: Full=Nicotinamide riboside kinase 1;
DE            Short=NRK 1;
DE            Short=NmR-K 1;
DE            EC=2.7.1.22;
DE   AltName: Full=Nicotinic acid riboside kinase 1;
DE            EC=2.7.1.173;
DE   AltName: Full=Ribosylnicotinamide kinase 1;
DE            Short=RNK 1;
DE   AltName: Full=Ribosylnicotinic acid kinase 1;
GN   Name=NMRK1; Synonyms=C9orf95, NRK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050262; F:ribosylnicotinamide kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004849; F:uridine kinase activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   NRK2_HUMAN              Reviewed;         230 AA.
AC   Q9NPI5; B7ZKR3; Q52M81; Q9NZK3;
DE   RecName: Full=Nicotinamide riboside kinase 2;
DE            Short=NRK 2;
DE            Short=NmR-K 2;
DE            EC=2.7.1.22;
DE   AltName: Full=Integrin beta-1-binding protein 3;
DE   AltName: Full=Muscle integrin-binding protein;
DE            Short=MIBP;
DE   AltName: Full=Nicotinic acid riboside kinase 2;
DE            EC=2.7.1.173;
DE   AltName: Full=Ribosylnicotinamide kinase 2;
DE            Short=RNK 2;
DE   AltName: Full=Ribosylnicotinic acid kinase 2;
GN   Name=NMRK2; Synonyms=ITGB1BP3, NRK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050262; F:ribosylnicotinamide kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IEA:Ensembl.
//
ID   NRK_HUMAN               Reviewed;        1582 AA.
AC   Q7Z2Y5; Q32ND6; Q5H9K2; Q6ZMP2;
DE   RecName: Full=Nik-related protein kinase;
DE            EC=2.7.11.1;
GN   Name=NRK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   NRL_HUMAN               Reviewed;         237 AA.
AC   P54845; Q53XD0;
DE   RecName: Full=Neural retina-specific leucine zipper protein;
DE            Short=NRL;
GN   Name=NRL; Synonyms=D14S46E;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045872; P:positive regulation of rhodopsin gene expression; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007468; P:regulation of rhodopsin gene expression; TAS:ProtInc.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0046548; P:retinal rod cell development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   NRM_HUMAN               Reviewed;         262 AA.
AC   Q8IXM6; B0S7R0; B0S7R1; I3XIE2; I3XIE3; Q5JP57; Q5JP58; Q5JP59;
AC   Q5JP60; Q8WU45; Q9BSX3; Q9UN92;
DE   RecName: Full=Nurim;
DE   AltName: Full=Nuclear envelope membrane protein;
DE   AltName: Full=Nuclear rim protein;
GN   Name=NRM; Synonyms=NRM29; ORFNames=UNQ555/PRO1112;
//
ID   NRN1L_HUMAN             Reviewed;         165 AA.
AC   Q496H8; Q6UWH7;
DE   RecName: Full=Neuritin-like protein;
DE   Flags: Precursor;
GN   Name=NRN1L; ORFNames=UNQ2446/PRO5725;
DR   GO; GO:0007399; P:nervous system development; IEA:InterPro.
//
ID   NRN1_HUMAN              Reviewed;         142 AA.
AC   Q9NPD7; B2RA93; Q7Z4Y1;
DE   RecName: Full=Neuritin;
DE   Flags: Precursor;
GN   Name=NRN1; Synonyms=NRN;
DR   GO; GO:0007399; P:nervous system development; IEA:InterPro.
//
ID   NRP1_HUMAN              Reviewed;         923 AA.
AC   O14786; B0LPG9; O60461; Q5T7F1; Q5T7F2; Q5T7F3; Q86T59; Q96I90;
AC   Q96IH5;
DE   RecName: Full=Neuropilin-1;
DE   AltName: Full=Vascular endothelial cell growth factor 165 receptor;
DE   AltName: CD_antigen=CD304;
DE   Flags: Precursor;
GN   Name=NRP1; Synonyms=NRP, VEGF165R;
DR   GO; GO:0015026; F:coreceptor activity; TAS:BHF-UCL.
DR   GO; GO:0019955; F:cytokine binding; NAS:BHF-UCL.
DR   GO; GO:0019838; F:growth factor binding; IPI:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017154; F:semaphorin receptor activity; NAS:BHF-UCL.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; ISS:BHF-UCL.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; NAS:BHF-UCL.
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0060385; P:axonogenesis involved in innervation; ISS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0071679; P:commissural neuron axon guidance; ISS:BHF-UCL.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0060666; P:dichotomous subdivision of terminal units involved in salivary gland branching; IEA:Ensembl.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0097102; P:endothelial tip cell fate specification; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; ISS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; ISS:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:BHF-UCL.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0050918; P:positive chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; ISS:BHF-UCL.
DR   GO; GO:0060301; P:positive regulation of cytokine activity; TAS:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; TAS:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; TAS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:1902336; P:positive regulation of retinal ganglion cell axon guidance; ISS:BHF-UCL.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; TAS:BHF-UCL.
DR   GO; GO:0090259; P:regulation of retinal ganglion cell axon guidance; ISS:BHF-UCL.
DR   GO; GO:0060627; P:regulation of vesicle-mediated transport; TAS:BHF-UCL.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; ISS:BHF-UCL.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; NAS:BHF-UCL.
DR   GO; GO:1902285; P:semaphorin-plexin signaling pathway involved in neuron projection guidance; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:BHF-UCL.
DR   GO; GO:0097490; P:sympathetic neuron projection extension; ISS:BHF-UCL.
DR   GO; GO:0097491; P:sympathetic neuron projection guidance; ISS:BHF-UCL.
DR   GO; GO:0021636; P:trigeminal nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
//
ID   NRP2_HUMAN              Reviewed;         931 AA.
AC   O60462; E9PF66; O14820; O14821; Q53TQ4; Q53TS3; Q7LBX7; Q9H2D4;
AC   Q9H2D5; Q9H2E2; Q9H2E3; Q9H2E4;
DE   RecName: Full=Neuropilin-2;
DE   AltName: Full=Vascular endothelial cell growth factor 165 receptor 2;
DE   Flags: Precursor;
GN   Name=NRP2; Synonyms=VEGF165R2;
DR   GO; GO:0019955; F:cytokine binding; NAS:BHF-UCL.
DR   GO; GO:0019838; F:growth factor binding; TAS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0017154; F:semaphorin receptor activity; NAS:UniProtKB.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; NAS:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0050919; P:negative chemotaxis; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; ISS:BHF-UCL.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; TAS:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; TAS:BHF-UCL.
DR   GO; GO:1902285; P:semaphorin-plexin signaling pathway involved in neuron projection guidance; ISS:BHF-UCL.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:BHF-UCL.
DR   GO; GO:0097490; P:sympathetic neuron projection extension; ISS:BHF-UCL.
DR   GO; GO:0097491; P:sympathetic neuron projection guidance; ISS:BHF-UCL.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; TAS:Reactome.
//
ID   NRROS_HUMAN             Reviewed;         692 AA.
AC   Q86YC3;
DE   RecName: Full=Negative regulator of reactive oxygen species;
DE   AltName: Full=Leucine-rich repeat-containing protein 33;
DE   Flags: Precursor;
GN   Name=NRROS; Synonyms=LRRC33; ORFNames=UNQ3030/PRO9833;
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   NRSN1_HUMAN             Reviewed;         195 AA.
AC   Q8IZ57; B2RAV4; Q8N8R6; Q96P21;
DE   RecName: Full=Neurensin-1;
DE   AltName: Full=Neuro-p24;
DE   AltName: Full=Vesicular membrane protein of 24 kDa;
DE            Short=Vesicular membrane protein p24;
GN   Name=NRSN1; Synonyms=VMP;
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
//
ID   NRSN2_HUMAN             Reviewed;         204 AA.
AC   Q9GZP1; A8K3B2; Q6FII5; Q9NUD3;
DE   RecName: Full=Neurensin-2;
GN   Name=NRSN2; Synonyms=C20orf98;
//
ID   NRTN_HUMAN              Reviewed;         197 AA.
AC   Q99748; B2RPE8;
DE   RecName: Full=Neurturin;
DE   Flags: Precursor;
GN   Name=NRTN;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:ProtInc.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001755; P:neural crest cell migration; IDA:MGI.
DR   GO; GO:0031175; P:neuron projection development; IDA:MGI.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   NRX1A_HUMAN             Reviewed;        1477 AA.
AC   Q9ULB1; A7KRL9; O60323; Q53TJ9; Q53TQ1; Q9C079; Q9C080; Q9C081;
AC   Q9H3M2; Q9UDM6;
DE   RecName: Full=Neurexin-1;
DE   AltName: Full=Neurexin I-alpha;
DE   AltName: Full=Neurexin-1-alpha;
DE   Flags: Precursor;
GN   Name=NRXN1; Synonyms=KIAA0578;
DR   GO; GO:0033130; F:acetylcholine receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005246; F:calcium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; ISS:BHF-UCL.
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0097109; F:neuroligin family protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0097116; P:gephyrin clustering; ISS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0097118; P:neuroligin clustering; ISS:BHF-UCL.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0007269; P:neurotransmitter secretion; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
DR   GO; GO:2000821; P:regulation of grooming behavior; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0042297; P:vocal learning; IMP:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   NRX1B_HUMAN             Reviewed;         442 AA.
AC   P58400;
DE   RecName: Full=Neurexin-1-beta;
DE   AltName: Full=Neurexin I-beta;
DE   Flags: Precursor;
GN   Name=NRXN1;
DR   GO; GO:0005246; F:calcium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0048306; F:calcium-dependent protein binding; ISS:BHF-UCL.
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097109; F:neuroligin family protein binding; ISS:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045184; P:establishment of protein localization; ISS:BHF-UCL.
DR   GO; GO:0097112; P:gamma-aminobutyric acid receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0097116; P:gephyrin clustering; ISS:BHF-UCL.
DR   GO; GO:0097117; P:guanylate kinase-associated protein clustering; ISS:BHF-UCL.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0097114; P:N-methyl-D-aspartate receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0051490; P:negative regulation of filopodium assembly; ISS:BHF-UCL.
DR   GO; GO:0097118; P:neuroligin clustering; ISS:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0023041; P:neuronal signal transduction; TAS:BHF-UCL.
DR   GO; GO:0007269; P:neurotransmitter secretion; ISS:BHF-UCL.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.
DR   GO; GO:0097120; P:receptor localization to synapse; ISS:BHF-UCL.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0097091; P:synaptic vesicle clustering; ISS:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   NRX2A_HUMAN             Reviewed;        1712 AA.
AC   Q9P2S2; A7E2C1; Q9Y2D6;
DE   RecName: Full=Neurexin-2;
DE   AltName: Full=Neurexin II-alpha;
DE   AltName: Full=Neurexin-2-alpha;
DE   Flags: Precursor;
GN   Name=NRXN2; Synonyms=KIAA0921;
DR   GO; GO:0005246; F:calcium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097109; F:neuroligin family protein binding; ISS:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0097116; P:gephyrin clustering; ISS:BHF-UCL.
DR   GO; GO:0097118; P:neuroligin clustering; ISS:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0007269; P:neurotransmitter secretion; ISS:BHF-UCL.
DR   GO; GO:0097119; P:postsynaptic density protein 95 clustering; ISS:BHF-UCL.
DR   GO; GO:0097104; P:postsynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0042297; P:vocal learning; IMP:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   NRX2B_HUMAN             Reviewed;         666 AA.
AC   P58401;
DE   RecName: Full=Neurexin-2-beta;
DE   AltName: Full=Neurexin II-beta;
DE   Flags: Precursor;
GN   Name=NRXN2;
DR   GO; GO:0050839; F:cell adhesion molecule binding; TAS:BHF-UCL.
DR   GO; GO:0097109; F:neuroligin family protein binding; TAS:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
//
ID   NRX3A_HUMAN             Reviewed;        1643 AA.
AC   Q9Y4C0; A6NGR4; A7MD34; O95378; Q8IUE3; Q9NS47; Q9P1V3; Q9P1V6;
AC   Q9UIE2; Q9UIE3; Q9ULA5; Q9Y486;
DE   RecName: Full=Neurexin-3;
DE   AltName: Full=Neurexin III-alpha;
DE   AltName: Full=Neurexin-3-alpha;
DE   Flags: Precursor;
GN   Name=NRXN3; Synonyms=C14orf60, KIAA0743;
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0050839; F:cell adhesion molecule binding; TAS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097109; F:neuroligin family protein binding; TAS:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0030534; P:adult behavior; IGI:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007612; P:learning; IGI:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:InterPro.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; IEA:InterPro.
DR   GO; GO:0035176; P:social behavior; IGI:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0071625; P:vocalization behavior; IGI:BHF-UCL.
//
ID   NRX3B_HUMAN             Reviewed;         637 AA.
AC   Q9HDB5; A5PKW8; A8MPU5; B3KPM7; Q6NUR0; Q8IUD8;
DE   RecName: Full=Neurexin-3-beta;
DE   AltName: Full=Neurexin III-beta;
DE   Contains:
DE     RecName: Full=Neurexin-3-beta, soluble form;
DE   Contains:
DE     RecName: Full=Neurexin-3-beta, C-terminal fragment;
DE              Short=NRXN3-CTF;
DE   Flags: Precursor;
GN   Name=NRXN3; Synonyms=KIAA0743;
DR   GO; GO:0050839; F:cell adhesion molecule binding; TAS:BHF-UCL.
DR   GO; GO:0097109; F:neuroligin family protein binding; TAS:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IGI:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007612; P:learning; IGI:BHF-UCL.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; TAS:BHF-UCL.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:InterPro.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; IEA:InterPro.
DR   GO; GO:0035176; P:social behavior; IGI:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; IEA:InterPro.
DR   GO; GO:0071625; P:vocalization behavior; IGI:BHF-UCL.
//
ID   NS1BP_HUMAN             Reviewed;         642 AA.
AC   Q9Y6Y0; A8K8R6; Q1G4T6; Q1G4T7; Q5TF75; Q6NW38; Q7LCG2; Q9NZX0;
AC   Q9Y480;
DE   RecName: Full=Influenza virus NS1A-binding protein;
DE            Short=NS1-BP;
DE            Short=NS1-binding protein;
DE   AltName: Full=Aryl hydrocarbon receptor-associated protein 3;
GN   Name=IVNS1ABP; Synonyms=ARA3, FLARA3, KIAA0850, NS1, NS1BP;
GN   ORFNames=HSPC068;
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NSA2_HUMAN              Reviewed;         260 AA.
AC   O95478;
DE   RecName: Full=Ribosome biogenesis protein NSA2 homolog;
DE   AltName: Full=Hairy cell leukemia protein 1;
DE   AltName: Full=TGF-beta-inducible nuclear protein 1;
GN   Name=NSA2; Synonyms=TINP1; ORFNames=HUSSY-29;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   NSD1_HUMAN              Reviewed;        2696 AA.
AC   Q96L73; Q96PD8; Q96RN7;
DE   RecName: Full=Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific;
DE            EC=2.1.1.43;
DE   AltName: Full=Androgen receptor coactivator 267 kDa protein;
DE   AltName: Full=Androgen receptor-associated protein of 267 kDa;
DE   AltName: Full=H3-K36-HMTase;
DE   AltName: Full=H4-K20-HMTase;
DE   AltName: Full=Lysine N-methyltransferase 3B;
DE   AltName: Full=Nuclear receptor-binding SET domain-containing protein 1;
DE            Short=NR-binding SET domain-containing protein;
GN   Name=NSD1; Synonyms=ARA267, KMT3B;
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.
DR   GO; GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IDA:UniProtKB.
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); ISS:UniProtKB.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; ISS:UniProtKB.
DR   GO; GO:0042974; F:retinoic acid receptor binding; ISS:UniProtKB.
DR   GO; GO:0046965; F:retinoid X receptor binding; ISS:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; ISS:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0010452; P:histone H3-K36 methylation; IDA:GOC.
DR   GO; GO:0034770; P:histone H4-K20 methylation; ISS:GOC.
DR   GO; GO:0016571; P:histone methylation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NSD2_HUMAN              Reviewed;        1365 AA.
AC   O96028; A2A2T2; A2A2T3; A2A2T4; A7MCZ1; D3DVQ2; O96031; Q4VBY8;
AC   Q672J1; Q6IS00; Q86V01; Q9BZB4; Q9UI92; Q9UPR2;
DE   RecName: Full=Histone-lysine N-methyltransferase NSD2;
DE            EC=2.1.1.43;
DE   AltName: Full=Multiple myeloma SET domain-containing protein;
DE            Short=MMSET;
DE   AltName: Full=Nuclear SET domain-containing protein 2;
DE            Short=NSD2;
DE   AltName: Full=Protein trithorax-5;
DE   AltName: Full=Wolf-Hirschhorn syndrome candidate 1 protein;
DE            Short=WHSC1;
GN   Name=WHSC1; Synonyms=KIAA1090, MMSET, NSD2, TRX5;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0003289; P:atrial septum primum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003290; P:atrial septum secundum morphogenesis; IEA:Ensembl.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0003149; P:membranous septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NSD3_HUMAN              Reviewed;        1437 AA.
AC   Q9BZ95; B7ZL11; D3DSX1; Q1RMD3; Q3B796; Q6ZSA5; Q9BYU8; Q9BYU9;
AC   Q9H2M8; Q9H9W9; Q9NXA6;
DE   RecName: Full=Histone-lysine N-methyltransferase NSD3;
DE            EC=2.1.1.43;
DE   AltName: Full=Nuclear SET domain-containing protein 3;
DE   AltName: Full=Protein whistle;
DE   AltName: Full=WHSC1-like 1 isoform 9 with methyltransferase activity to lysine;
DE   AltName: Full=Wolf-Hirschhorn syndrome candidate 1-like protein 1;
DE            Short=WHSC1-like protein 1;
GN   Name=WHSC1L1; Synonyms=NSD3; ORFNames=DC28;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034968; P:histone lysine methylation; IDA:GOC.
DR   GO; GO:0016571; P:histone methylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NSDHL_HUMAN             Reviewed;         373 AA.
AC   Q15738; D3DWT6; O00344;
DE   RecName: Full=Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating;
DE            EC=1.1.1.170;
DE   AltName: Full=Protein H105e3;
GN   Name=NSDHL; Synonyms=H105E3;
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0047012; F:sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   NSE1_HUMAN              Reviewed;         266 AA.
AC   Q8WV22; D3DWF6; Q9P045; Q9P049;
DE   RecName: Full=Non-structural maintenance of chromosomes element 1 homolog;
DE            Short=Non-SMC element 1 homolog;
DE            EC=6.3.2.-;
GN   Name=NSMCE1; ORFNames=HSPC333, HSPC337;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:GOC.
//
ID   NSE2_HUMAN              Reviewed;         247 AA.
AC   Q96MF7; Q8N549;
DE   RecName: Full=E3 SUMO-protein ligase NSE2;
DE            EC=6.3.2.-;
DE   AltName: Full=MMS21 homolog;
DE            Short=hMMS21;
DE   AltName: Full=Non-structural maintenance of chromosomes element 2 homolog;
DE            Short=Non-SMC element 2 homolog;
GN   Name=NSMCE2; Synonyms=C8orf36, MMS21;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0090398; P:cellular senescence; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
//
ID   NSE4A_HUMAN             Reviewed;         385 AA.
AC   Q9NXX6; Q5SQQ5; Q6P673; Q8WY66; Q9BS90;
DE   RecName: Full=Non-structural maintenance of chromosomes element 4 homolog A;
DE            Short=NS4EA;
DE            Short=Non-SMC element 4 homolog A;
GN   Name=NSMCE4A; Synonyms=C10orf86; ORFNames=PP4762;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.
//
ID   NSF1C_HUMAN             Reviewed;         370 AA.
AC   Q9UNZ2; A2A2L1; B2RD74; Q5JXA4; Q5JXA5; Q7Z533; Q9H102; Q9NVL9;
AC   Q9UI06;
DE   RecName: Full=NSFL1 cofactor p47;
DE   AltName: Full=UBX domain-containing protein 2C;
DE   AltName: Full=p97 cofactor p47;
GN   Name=NSFL1C; Synonyms=UBXN2C;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NSF_HUMAN               Reviewed;         744 AA.
AC   P46459; A8K2D9; Q8N6D7; Q9UKZ2;
DE   RecName: Full=Vesicle-fusing ATPase;
DE            EC=3.6.4.6;
DE   AltName: Full=N-ethylmaleimide-sensitive fusion protein;
DE            Short=NEM-sensitive fusion protein;
DE   AltName: Full=Vesicular-fusion protein NSF;
GN   Name=NSF;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042623; F:ATPase activity, coupled; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; TAS:UniProtKB.
DR   GO; GO:0045026; P:plasma membrane fusion; TAS:UniProtKB.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IDA:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   NSG1_HUMAN              Reviewed;         185 AA.
AC   P42857; B4DXC5; Q49AQ1;
DE   RecName: Full=Neuron-specific protein family member 1;
DE   AltName: Full=Brain neuron cytoplasmic protein 1;
GN   Name=NSG1; Synonyms=D4S234;
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:InterPro.
//
ID   NSGX_HUMAN              Reviewed;          79 AA.
AC   Q9UH64; Q5VVJ4;
DE   RecName: Full=Susceptibility protein NSG-x;
GN   Name=C9orf53;
//
ID   NSG2_HUMAN              Reviewed;         171 AA.
AC   Q9Y328; B2R5Y0; D3DQN0; Q9UHX8;
DE   RecName: Full=Neuron-specific protein family member 2;
DE   AltName: Full=Protein p19;
DE            Short=Hmp19;
GN   Name=NSG2;
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:InterPro.
//
ID   NSMA2_HUMAN             Reviewed;         655 AA.
AC   Q9NY59; B7ZL82; Q2M1S8;
DE   RecName: Full=Sphingomyelin phosphodiesterase 3;
DE            EC=3.1.4.12;
DE   AltName: Full=Neutral sphingomyelinase 2;
DE            Short=nSMase-2;
DE            Short=nSMase2;
DE   AltName: Full=Neutral sphingomyelinase II;
GN   Name=SMPD3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0030072; P:peptide hormone secretion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006685; P:sphingomyelin catabolic process; TAS:ProtInc.
//
ID   NSL1_HUMAN              Reviewed;         281 AA.
AC   Q96IY1; E7ETD5; Q5SY75; Q9H2M5; Q9NRN8; Q9Y415;
DE   RecName: Full=Kinetochore-associated protein NSL1 homolog;
GN   Name=NSL1; Synonyms=C1orf48; ORFNames=DC31, DC8, MIS14;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   NSMA3_HUMAN             Reviewed;         827 AA.
AC   Q9NXE4; B4DM23; B4DQ31; B4DRB8; B4E0L6; E7ESA2; Q6FI76; Q6P1P7;
AC   Q6ZT43; Q9H0M2; Q9NW20; Q9NWL2; Q9P2C9;
DE   RecName: Full=Sphingomyelin phosphodiesterase 4;
DE            EC=3.1.4.12;
DE   AltName: Full=Neutral sphingomyelinase 3;
DE            Short=nSMase-3;
DE            Short=nSMase3;
DE   AltName: Full=Neutral sphingomyelinase III;
GN   Name=SMPD4; Synonyms=KIAA1418;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; TAS:Reactome.
DR   GO; GO:0050290; F:sphingomyelin phosphodiesterase D activity; IEA:InterPro.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0046475; P:glycerophospholipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006685; P:sphingomyelin catabolic process; IDA:HGNC.
//
ID   NSMA_HUMAN              Reviewed;         423 AA.
AC   O60906; Q5TED1; Q9BWR3;
DE   RecName: Full=Sphingomyelin phosphodiesterase 2;
DE            EC=3.1.4.12;
DE   AltName: Full=Lyso-platelet-activating factor-phospholipase C;
DE            Short=Lyso-PAF-PLC;
DE   AltName: Full=Neutral sphingomyelinase;
DE            Short=N-SMase;
DE            Short=nSMase;
GN   Name=SMPD2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006684; P:sphingomyelin metabolic process; TAS:ProtInc.
//
ID   NSN5C_HUMAN             Reviewed;         315 AA.
AC   Q63ZY6; A8K7U2; Q3KQU7; Q658S2; Q6NZ66; Q6PHS1; Q8N727; Q9HAH4;
DE   RecName: Full=Putative methyltransferase NSUN5C;
DE            EC=2.1.1.-;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 5C;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 20C protein;
GN   Name=NSUN5P2; Synonyms=NSUN5C, WBSCR20B, WBSCR20C;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   NSMF_HUMAN              Reviewed;         530 AA.
AC   Q6X4W1; Q2TB96; Q6X4V7; Q6X4V8; Q6X4V9; Q8N2M2; Q96SY1; Q9NPM4;
AC   Q9NPP3; Q9NPS3;
DE   RecName: Full=NMDA receptor synaptonuclear signaling and neuronal migration factor;
DE   AltName: Full=Nasal embryonic luteinizing hormone-releasing hormone factor;
DE            Short=Nasal embryonic LHRH factor;
GN   Name=NSMF; Synonyms=NELF;
DR   GO; GO:0048306; F:calcium-dependent protein binding; ISS:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; ISS:UniProtKB.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.
DR   GO; GO:2001224; P:positive regulation of neuron migration; IMP:UniProtKB.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; ISS:UniProtKB.
//
ID   NSN5B_HUMAN             Reviewed;         163 AA.
AC   Q3KNT7; B3KX24; Q52LC6; Q8N728;
DE   RecName: Full=Putative NOL1/NOP2/Sun domain family member 5B;
DE            EC=2.1.1.-;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 20B protein;
GN   Name=NSUN5P1; Synonyms=NSUN5B, WBSCR20B;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   NSRP1_HUMAN             Reviewed;         558 AA.
AC   Q9H0G5; Q6FI71;
DE   RecName: Full=Nuclear speckle splicing regulatory protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 55;
DE   AltName: Full=Nuclear speckle-related protein 70;
DE            Short=NSrp70;
GN   Name=NSRP1; Synonyms=CCDC55, NSRP70;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032502; P:developmental process; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   NSUN2_HUMAN             Reviewed;         767 AA.
AC   Q08J23; A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; Q9BVN4; Q9H858;
AC   Q9NXD9;
DE   RecName: Full=tRNA (cytosine(34)-C(5))-methyltransferase;
DE            EC=2.1.1.203;
DE   AltName: Full=Myc-induced SUN domain-containing protein;
DE            Short=Misu;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 2;
DE   AltName: Full=Substrate of AIM1/Aurora kinase B;
DE   AltName: Full=tRNA (cytosine-5-)-methyltransferase;
DE   AltName: Full=tRNA methyltransferase 4 homolog;
DE            Short=hTrm4;
GN   Name=NSUN2; Synonyms=SAKI, TRM4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0016428; F:tRNA (cytosine-5-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0030488; P:tRNA methylation; IDA:UniProtKB.
//
ID   NSUN3_HUMAN             Reviewed;         340 AA.
AC   Q9H649; Q6PG41; Q8IXG9; Q9H6M2;
DE   RecName: Full=Putative methyltransferase NSUN3;
DE            EC=2.1.1.-;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 3;
GN   Name=NSUN3; ORFNames=MSTP077, UG0651E06;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   NSUN4_HUMAN             Reviewed;         384 AA.
AC   Q96CB9; A8K6S6; B3KQ50; B4DHA4; Q5TDF7; Q96AN8; Q9HAJ8;
DE   RecName: Full=5-methylcytosine rRNA methyltransferase NSUN4;
DE            EC=2.1.1.-;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 4;
DE   Flags: Precursor;
GN   Name=NSUN4;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   NSUN5_HUMAN             Reviewed;         429 AA.
AC   Q96P11; B3KX04; B4DP79; G3V0G9; Q6ZUI8; Q96HT9; Q9NW70;
DE   RecName: Full=Putative methyltransferase NSUN5;
DE            EC=2.1.1.-;
DE   AltName: Full=NOL1-related protein;
DE            Short=NOL1R;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 5;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 20A protein;
GN   Name=NSUN5; Synonyms=WBSCR20, WBSCR20A;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NSUN6_HUMAN             Reviewed;         469 AA.
AC   Q8TEA1; B0YJ54;
DE   RecName: Full=Putative methyltransferase NSUN6;
DE            EC=2.1.1.-;
DE   AltName: Full=NOL1/NOP2/Sun and PUA domain-containing protein 1;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 6;
GN   Name=NSUN6; Synonyms=NOPD1;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   NSUN7_HUMAN             Reviewed;         718 AA.
AC   Q8NE18; C9JI19; Q8N9K8; Q9H815;
DE   RecName: Full=Putative methyltransferase NSUN7;
DE            EC=2.1.1.-;
DE   AltName: Full=NOL1/NOP2/Sun domain family member 7;
GN   Name=NSUN7;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   NT2NL_HUMAN             Reviewed;         236 AA.
AC   Q7Z3S9; Q5BKT8; Q5VTG9; Q5XG84; Q6P192; Q8NC23; Q8WUQ9; Q96FY1;
DE   RecName: Full=Notch homolog 2 N-terminal-like protein;
GN   Name=NOTCH2NL; Synonyms=N2N;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
//
ID   NT5C_HUMAN              Reviewed;         201 AA.
AC   Q8TCD5; Q96HS6; Q9NP82;
DE   RecName: Full=5'(3')-deoxyribonucleotidase, cytosolic type;
DE            EC=3.1.3.-;
DE   AltName: Full=Cytosolic 5',3'-pyrimidine nucleotidase;
DE   AltName: Full=Deoxy-5'-nucleotidase 1;
DE            Short=dNT-1;
GN   Name=NT5C; Synonyms=DNT1, UMPH2;
DR   GO; GO:0008253; F:5'-nucleotidase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008252; F:nucleotidase activity; IDA:UniProtKB.
DR   GO; GO:0019103; F:pyrimidine nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0009223; P:pyrimidine deoxyribonucleotide catabolic process; IDA:UniProtKB.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NT5D2_HUMAN             Reviewed;         520 AA.
AC   Q9H857; C9JTZ6; E9PAL9; O95888; Q96C80; Q9H9Z8;
DE   RecName: Full=5'-nucleotidase domain-containing protein 2;
DE            EC=3.1.3.-;
GN   Name=NT5DC2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NT5D3_HUMAN             Reviewed;         548 AA.
AC   Q86UY8; Q9NUM7; Q9P2T2; Q9P2T3;
DE   RecName: Full=5'-nucleotidase domain-containing protein 3;
DE            EC=3.1.3.-;
DE   AltName: Full=GRP94-neighboring nucleotidase;
GN   Name=NT5DC3; Synonyms=GNN, TU12B1-TY;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NT5D1_HUMAN             Reviewed;         455 AA.
AC   Q5TFE4; B2RND9; B3KR35; Q6XYD5;
DE   RecName: Full=5'-nucleotidase domain-containing protein 1;
DE            EC=3.1.3.-;
GN   Name=NT5DC1; Synonyms=NT5C2L1; ORFNames=LP2642;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NT5D4_HUMAN             Reviewed;         428 AA.
AC   Q86YG4;
DE   RecName: Full=5'-nucleotidase domain-containing protein 4;
GN   Name=NT5DC4;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NT5M_HUMAN              Reviewed;         228 AA.
AC   Q9NPB1;
DE   RecName: Full=5'(3')-deoxyribonucleotidase, mitochondrial;
DE            Short=5',3'-nucleotidase, mitochondrial;
DE            EC=3.1.3.-;
DE   AltName: Full=Deoxy-5'-nucleotidase 2;
DE            Short=dNT-2;
DE   Flags: Precursor;
GN   Name=NT5M; Synonyms=DNT2;
DR   GO; GO:0008253; F:5'-nucleotidase activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008252; F:nucleotidase activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0016311; P:dephosphorylation; EXP:GOC.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0046079; P:dUMP catabolic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009223; P:pyrimidine deoxyribonucleotide catabolic process; TAS:ProtInc.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NTAL_HUMAN              Reviewed;         243 AA.
AC   Q9GZY6; A6NFK6; A8K209; A8K4F1; D3DXF9; Q9BXX8; Q9NZY9;
DE   RecName: Full=Linker for activation of T-cells family member 2;
DE   AltName: Full=Linker for activation of B-cells;
DE   AltName: Full=Membrane-associated adapter molecule;
DE   AltName: Full=Non-T-cell activation linker;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 15 protein;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 5 protein;
GN   Name=LAT2; Synonyms=LAB, NTAL, WBS15, WBSCR15, WBSCR5;
GN   ORFNames=HSPC046;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042169; F:SH2 domain binding; IMP:HGNC.
DR   GO; GO:0042113; P:B cell activation; IDA:HGNC.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0019722; P:calcium-mediated signaling; IGI:HGNC.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IGI:HGNC.
DR   GO; GO:0043303; P:mast cell degranulation; IEA:UniProtKB-KW.
//
ID   NTAN1_HUMAN             Reviewed;         310 AA.
AC   Q96AB6; Q7Z4Z0;
DE   RecName: Full=Protein N-terminal asparagine amidohydrolase;
DE            EC=3.5.1.-;
DE   AltName: Full=Protein NH2-terminal asparagine amidohydrolase;
DE            Short=PNAA;
DE   AltName: Full=Protein NH2-terminal asparagine deamidase;
DE            Short=PNAD;
DE            Short=Protein N-terminal Asn amidase;
DE            Short=Protein N-terminal asparagine amidase;
DE            Short=Protein NTN-amidase;
GN   Name=NTAN1;
DR   GO; GO:0008418; F:protein-N-terminal asparagine amidohydrolase activity; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
//
ID   NTAQ1_HUMAN             Reviewed;         205 AA.
AC   Q96HA8; Q9NW95;
DE   RecName: Full=Protein N-terminal glutamine amidohydrolase;
DE            EC=3.5.1.-;
DE   AltName: Full=Protein NH2-terminal glutamine deamidase;
DE            Short=N-terminal Gln amidase;
DE            Short=Nt(Q)-amidase;
DE   AltName: Full=WDYHV motif-containing protein 1;
GN   Name=WDYHV1; Synonyms=C8orf32, NTAQ1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070773; F:protein-N-terminal glutamine amidohydrolase activity; ISS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; ISS:UniProtKB.
//
ID   NTCP2_HUMAN             Reviewed;         348 AA.
AC   Q12908; A1L4F4; Q13839;
DE   RecName: Full=Ileal sodium/bile acid cotransporter;
DE   AltName: Full=Apical sodium-dependent bile acid transporter;
DE            Short=ASBT;
DE   AltName: Full=Ileal Na(+)/bile acid cotransporter;
DE   AltName: Full=Ileal sodium-dependent bile acid transporter;
DE            Short=IBAT;
DE            Short=ISBT;
DE   AltName: Full=Na(+)-dependent ileal bile acid transporter;
DE   AltName: Full=Sodium/taurocholate cotransporting polypeptide, ileal;
DE   AltName: Full=Solute carrier family 10 member 2;
GN   Name=SLC10A2; Synonyms=ASBT, ISBT, NTCP2;
DR   GuidetoPHARMACOLOGY; 960; -.
DR   GO; GO:0008508; F:bile acid:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   NTCP4_HUMAN             Reviewed;         437 AA.
AC   Q96EP9; Q8WUZ2;
DE   RecName: Full=Sodium/bile acid cotransporter 4;
DE   AltName: Full=Na(+)/bile acid cotransporter 4;
DE   AltName: Full=Solute carrier family 10 member 4;
GN   Name=SLC10A4;
DR   GO; GO:0008508; F:bile acid:sodium symporter activity; IEA:InterPro.
//
ID   NTCP5_HUMAN             Reviewed;         438 AA.
AC   Q5PT55; B2RN26;
DE   RecName: Full=Sodium/bile acid cotransporter 5;
DE   AltName: Full=Na(+)/bile acid cotransporter 5;
DE   AltName: Full=Solute carrier family 10 member 5;
DE   Flags: Precursor;
GN   Name=SLC10A5;
DR   GO; GO:0008508; F:bile acid:sodium symporter activity; IEA:InterPro.
//
ID   NTCP7_HUMAN             Reviewed;         358 AA.
AC   Q0GE19; A7E2E6; A7MAX9; Q0VAP9; Q45NG1; Q45NG2; Q5H9S6; Q6P4E6;
AC   Q8IZ62; Q8NBP8; Q9H0M9;
DE   RecName: Full=Sodium/bile acid cotransporter 7;
DE   AltName: Full=Na(+)/bile acid cotransporter 7;
DE   AltName: Full=Solute carrier family 10 member 7;
GN   Name=SLC10A7; Synonyms=C4orf13, P7; ORFNames=PSEC0051;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   NTCP_HUMAN              Reviewed;         349 AA.
AC   Q14973; B9EGB6; Q2TU29;
DE   RecName: Full=Sodium/bile acid cotransporter;
DE   AltName: Full=Cell growth-inhibiting gene 29 protein;
DE   AltName: Full=Na(+)/bile acid cotransporter;
DE   AltName: Full=Na(+)/taurocholate transport protein;
DE   AltName: Full=Sodium/taurocholate cotransporting polypeptide;
DE   AltName: Full=Solute carrier family 10 member 1;
GN   Name=SLC10A1; Synonyms=NTCP; ORFNames=GIG29;
DR   GuidetoPHARMACOLOGY; 959; -.
DR   GO; GO:0008508; F:bile acid:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   NTF2_HUMAN              Reviewed;         127 AA.
AC   P61970; B2R4G7; P13662; Q6IB67;
DE   RecName: Full=Nuclear transport factor 2;
DE            Short=NTF-2;
DE   AltName: Full=Placental protein 15;
DE            Short=PP15;
GN   Name=NUTF2; Synonyms=NTF2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.
//
ID   NTF3_HUMAN              Reviewed;         257 AA.
AC   P20783; B7Z1T5; Q6FH50;
DE   RecName: Full=Neurotrophin-3;
DE            Short=NT-3;
DE   AltName: Full=HDNF;
DE   AltName: Full=Nerve growth factor 2;
DE            Short=NGF-2;
DE   AltName: Full=Neurotrophic factor;
DE   Flags: Precursor;
GN   Name=NTF3;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0032856; P:activation of Ras GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0007403; P:glial cell fate determination; IEA:Ensembl.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0042490; P:mechanoreceptor differentiation; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045687; P:positive regulation of glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050804; P:regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:BHF-UCL.
//
ID   NTF4_HUMAN              Reviewed;         210 AA.
AC   P34130; Q6FH56;
DE   RecName: Full=Neurotrophin-4;
DE            Short=NT-4;
DE   AltName: Full=Neurotrophin-5;
DE            Short=NT-5;
DE   AltName: Full=Neutrophic factor 4;
DE   Flags: Precursor;
GN   Name=NTF4; Synonyms=NTF5;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0008344; P:adult locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; ISS:UniProtKB.
DR   GO; GO:0007402; P:ganglion mother cell fate determination; ISS:UniProtKB.
DR   GO; GO:0007616; P:long-term memory; ISS:UniProtKB.
DR   GO; GO:0042490; P:mechanoreceptor differentiation; IEA:Ensembl.
DR   GO; GO:0008052; P:sensory organ boundary specification; ISS:UniProtKB.
//
ID   NTH_HUMAN               Reviewed;         312 AA.
AC   P78549; Q1MVR1; Q99566; Q99794; Q9BPX2;
DE   RecName: Full=Endonuclease III-like protein 1;
DE            Short=hNTH1;
DE            EC=3.2.2.-;
DE            EC=4.2.99.18;
DE   AltName: Full=Bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase;
DE            Short=DNA glycoslyase/AP lyase;
DE   Flags: Precursor;
GN   Name=NTHL1; Synonyms=NTH1, OCTS3;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0019104; F:DNA N-glycosylase activity; IDA:UniProtKB.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; IDA:UniProtKB.
DR   GO; GO:0045008; P:depyrimidination; TAS:Reactome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006296; P:nucleotide-excision repair, DNA incision, 5'-to lesion; IDA:UniProtKB.
//
ID   NTKL_HUMAN              Reviewed;         808 AA.
AC   Q96KG9; A6NJF1; Q96G50; Q96KG8; Q96KH1; Q9HAW5; Q9HBL3; Q9NR53;
DE   RecName: Full=N-terminal kinase-like protein;
DE   AltName: Full=Coated vesicle-associated kinase of 90 kDa;
DE   AltName: Full=SCY1-like protein 1;
DE   AltName: Full=Telomerase regulation-associated protein;
DE   AltName: Full=Telomerase transcriptional element-interacting factor;
DE   AltName: Full=Teratoma-associated tyrosine kinase;
GN   Name=SCYL1; Synonyms=CVAK90, GKLP, NTKL, TAPK, TEIF, TRAP;
GN   ORFNames=HT019;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; NAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NTM1A_HUMAN             Reviewed;         223 AA.
AC   Q9BV86; A8K4J2; A8K8G7; Q5SZB9; Q9UI28;
DE   RecName: Full=N-terminal Xaa-Pro-Lys N-methyltransferase 1;
DE            EC=2.1.1.244;
DE   AltName: Full=Alpha N-terminal protein methyltransferase 1A;
DE   AltName: Full=Methyltransferase-like protein 11A;
DE   AltName: Full=N-terminal RCC1 methyltransferase;
DE   AltName: Full=X-Pro-Lys N-terminal protein methyltransferase 1A;
DE            Short=NTM1A;
DE   Contains:
DE     RecName: Full=N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed;
GN   Name=NTMT1; Synonyms=C9orf32, METTL11A, NRMT, NRMT1; ORFNames=AD-003;
DR   GO; GO:0008276; F:protein methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0018012; P:N-terminal peptidyl-alanine trimethylation; IEA:Ensembl.
DR   GO; GO:0018016; P:N-terminal peptidyl-proline dimethylation; IDA:UniProtKB.
DR   GO; GO:0035572; P:N-terminal peptidyl-serine dimethylation; IDA:UniProtKB.
DR   GO; GO:0035573; P:N-terminal peptidyl-serine trimethylation; IDA:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   NTM1B_HUMAN             Reviewed;         283 AA.
AC   Q5VVY1; B2RXI0;
DE   RecName: Full=Alpha N-terminal protein methyltransferase 1B;
DE            EC=2.1.1.299;
DE   AltName: Full=Methyltransferase-like protein 11B;
DE   AltName: Full=X-Pro-Lys N-terminal protein methyltransferase 1B;
DE            Short=NTM1B;
GN   Name=METTL11B; Synonyms=C1orf184, NRMT2;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   NTM2D_HUMAN             Reviewed;         806 AA.
AC   Q5VT03; A6NGV9;
DE   RecName: Full=NUT family member 2D;
GN   Name=NUTM2D; Synonyms=FAM22D;
//
ID   NTM2E_HUMAN             Reviewed;         878 AA.
AC   B1AL46; A6NHL0;
DE   RecName: Full=NUT family member 2E;
GN   Name=NUTM2E; Synonyms=FAM22E;
//
ID   NTM2B_HUMAN             Reviewed;         878 AA.
AC   A6NNL0; A6NM73;
DE   RecName: Full=NUT family member 2B;
GN   Name=NUTM2B; Synonyms=FAM22B;
//
ID   NTM2F_HUMAN             Reviewed;         756 AA.
AC   A1L443; B6ZDF0; Q5SR58; Q5SR59; Q9UFB1;
DE   RecName: Full=NUT family member 2F;
GN   Name=NUTM2F; Synonyms=FAM22F;
//
ID   NTM2G_HUMAN             Reviewed;         741 AA.
AC   Q5VZR2; A6NNI5; Q5VZR3;
DE   RecName: Full=NUT family member 2G;
GN   Name=NUTM2G; Synonyms=FAM22G;
//
ID   NTM2A_HUMAN             Reviewed;         878 AA.
AC   Q8IVF1; A6NMX5; C9JDI1; Q5VZW1;
DE   RecName: Full=NUT family member 2A;
GN   Name=NUTM2A; Synonyms=FAM22A, KIAA2020;
//
ID   NTNG1_HUMAN             Reviewed;         539 AA.
AC   Q9Y2I2; Q5VU86; Q5VU87; Q5VU89; Q5VU90; Q5VU91; Q7Z2Y3; Q8N633;
DE   RecName: Full=Netrin-G1;
DE   AltName: Full=Laminet-1;
DE   Flags: Precursor;
GN   Name=NTNG1; Synonyms=KIAA0976, LMNT1; ORFNames=UNQ571/PRO1133;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
//
ID   NTNG2_HUMAN             Reviewed;         530 AA.
AC   Q96CW9; Q5JUJ2; Q6UXY0; Q96JH0;
DE   RecName: Full=Netrin-G2;
DE   AltName: Full=Laminet-2;
DE   Flags: Precursor;
GN   Name=NTNG2; Synonyms=KIAA1857, LMNT2; ORFNames=UNQ9381/PRO34206;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
//
ID   NTPCR_HUMAN             Reviewed;         190 AA.
AC   Q9BSD7;
DE   RecName: Full=Cancer-related nucleoside-triphosphatase;
DE            Short=NTPase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
GN   Name=NTPCR; Synonyms=C1orf57;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0098519; F:nucleotide phosphatase activity, acting on free nucleotides; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NTR1_HUMAN              Reviewed;         418 AA.
AC   P30989; Q9H4H1; Q9H4T5;
DE   RecName: Full=Neurotensin receptor type 1;
DE            Short=NT-R-1;
DE            Short=NTR1;
DE   AltName: Full=High-affinity levocabastine-insensitive neurotensin receptor;
DE   AltName: Full=NTRH;
GN   Name=NTSR1; Synonyms=NTRR;
DR   GuidetoPHARMACOLOGY; 309; -.
DR   GO; GO:0016492; F:G-protein coupled neurotensin receptor activity; IMP:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IMP:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   NTR2_HUMAN              Reviewed;         410 AA.
AC   O95665; Q53QQ5; Q57Z87; Q8IY58; Q8TBH6;
DE   RecName: Full=Neurotensin receptor type 2;
DE            Short=NT-R-2;
DE            Short=NTR2;
DE   AltName: Full=Levocabastine-sensitive neurotensin receptor;
GN   Name=NTSR2;
DR   GuidetoPHARMACOLOGY; 310; -.
DR   GO; GO:0016492; F:G-protein coupled neurotensin receptor activity; IEA:Ensembl.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
//
ID   NTRI_HUMAN              Reviewed;         344 AA.
AC   Q9P121; A0MTT2; Q6UXJ3; Q86VJ9;
DE   RecName: Full=Neurotrimin;
DE            Short=hNT;
DE   AltName: Full=IgLON family member 2;
DE   Flags: Precursor;
GN   Name=NTM; Synonyms=IGLON2, NT; ORFNames=UNQ297/PRO337;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0008038; P:neuron recognition; TAS:ProtInc.
//
ID   NTRK1_HUMAN             Reviewed;         796 AA.
AC   P04629; B2R6T5; B7ZM34; P08119; Q15655; Q15656; Q5D056; Q5VZS2;
AC   Q7Z5C3; Q9UIU7;
DE   RecName: Full=High affinity nerve growth factor receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=Neurotrophic tyrosine kinase receptor type 1;
DE   AltName: Full=TRK1-transforming tyrosine kinase protein;
DE   AltName: Full=Tropomyosin-related kinase A;
DE   AltName: Full=Tyrosine kinase receptor;
DE   AltName: Full=Tyrosine kinase receptor A;
DE            Short=Trk-A;
DE   AltName: Full=gp140trk;
DE   AltName: Full=p140-TrkA;
DE   Flags: Precursor;
GN   Name=NTRK1; Synonyms=MTC, TRK, TRKA;
DR   GuidetoPHARMACOLOGY; 1817; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048406; F:nerve growth factor binding; IDA:UniProtKB.
DR   GO; GO:0010465; F:nerve growth factor receptor activity; IDA:UniProtKB.
DR   GO; GO:0043121; F:neurotrophin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:Reactome.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0060385; P:axonogenesis involved in innervation; ISS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0071316; P:cellular response to nicotine; IEA:Ensembl.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050965; P:detection of temperature stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0010623; P:developmental programmed cell death; ISS:UniProtKB.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0042490; P:mechanoreceptor differentiation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0021553; P:olfactory nerve development; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; ISS:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051599; P:response to hydrostatic pressure; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:Reactome.
//
ID   NTRK2_HUMAN             Reviewed;         822 AA.
AC   Q16620; B1ANZ4; B4DFV9; Q16675; Q59GJ1; Q8WXJ5; Q8WXJ6; Q8WXJ7;
DE   RecName: Full=BDNF/NT-3 growth factors receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=GP145-TrkB;
DE            Short=Trk-B;
DE   AltName: Full=Neurotrophic tyrosine kinase receptor type 2;
DE   AltName: Full=TrkB tyrosine kinase;
DE   AltName: Full=Tropomyosin-related kinase B;
DE   Flags: Precursor;
GN   Name=NTRK2; Synonyms=TRKB;
DR   GuidetoPHARMACOLOGY; 1818; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048403; F:brain-derived neurotrophic factor binding; ISS:UniProtKB.
DR   GO; GO:0060175; F:brain-derived neurotrophic factor-activated receptor activity; IMP:UniProtKB.
DR   GO; GO:0043121; F:neurotrophin binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0031547; P:brain-derived neurotrophic factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IEA:Ensembl.
DR   GO; GO:0021954; P:central nervous system neuron development; ISS:UniProtKB.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:UniProtKB.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0014047; P:glutamate secretion; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; ISS:UniProtKB.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0042490; P:mechanoreceptor differentiation; IEA:Ensembl.
DR   GO; GO:2000811; P:negative regulation of anoikis; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0050773; P:regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.
DR   GO; GO:0010996; P:response to auditory stimulus; IEA:Ensembl.
DR   GO; GO:0046548; P:retinal rod cell development; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:Reactome.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   NTRK3_HUMAN             Reviewed;         839 AA.
AC   Q16288; B7Z4C5; E9PG56; H0YND1; O75682; Q12827; Q16289;
DE   RecName: Full=NT-3 growth factor receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=GP145-TrkC;
DE            Short=Trk-C;
DE   AltName: Full=Neurotrophic tyrosine kinase receptor type 3;
DE   AltName: Full=TrkC tyrosine kinase;
DE   Flags: Precursor;
GN   Name=NTRK3; Synonyms=TRKC;
DR   GuidetoPHARMACOLOGY; 1819; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043121; F:neurotrophin binding; TAS:ProtInc.
DR   GO; GO:0005030; F:neurotrophin receptor activity; IDA:BHF-UCL.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0032856; P:activation of Ras GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0042490; P:mechanoreceptor differentiation; IEA:Ensembl.
DR   GO; GO:0019056; P:modulation by virus of host transcription; IEA:Ensembl.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0038179; P:neurotrophin signaling pathway; IDA:GOC.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0048691; P:positive regulation of axon extension involved in regeneration; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:BHF-UCL.
//
ID   NU107_HUMAN             Reviewed;         925 AA.
AC   P57740; B4DZ67; Q6PJE1;
DE   RecName: Full=Nuclear pore complex protein Nup107;
DE   AltName: Full=107 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup107;
GN   Name=NUP107;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IMP:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU133_HUMAN             Reviewed;        1156 AA.
AC   Q8WUM0; B2RAZ8; Q5T8N0; Q9H9W2; Q9NV71; Q9NVC4;
DE   RecName: Full=Nuclear pore complex protein Nup133;
DE   AltName: Full=133 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup133;
GN   Name=NUP133;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006999; P:nuclear pore organization; IMP:UniProtKB.
DR   GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU153_HUMAN             Reviewed;        1475 AA.
AC   P49790; E7EPX5; Q4LE47; Q5T9I7; Q7Z743;
DE   RecName: Full=Nuclear pore complex protein Nup153;
DE   AltName: Full=153 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup153;
GN   Name=NUP153;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
DR   GO; GO:0043495; F:protein anchor; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IMP:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0046832; P:negative regulation of RNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU155_HUMAN             Reviewed;        1391 AA.
AC   O75694; Q9UBE9; Q9UFL5;
DE   RecName: Full=Nuclear pore complex protein Nup155;
DE   AltName: Full=155 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup155;
GN   Name=NUP155; Synonyms=KIAA0791;
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:Ensembl.
DR   GO; GO:0006998; P:nuclear envelope organization; IDA:MGI.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU160_HUMAN             Reviewed;        1436 AA.
AC   Q12769; B4DYE8; B4E2J9; Q08AD3; Q7Z5X6; Q96GB3; Q9H660;
DE   RecName: Full=Nuclear pore complex protein Nup160;
DE   AltName: Full=160 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup160;
GN   Name=NUP160; Synonyms=KIAA0197, NUP120;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU188_HUMAN             Reviewed;        1749 AA.
AC   Q5SRE5; Q14675; Q2TA87; Q7Z3K8; Q8IWF1;
DE   RecName: Full=Nucleoporin NUP188 homolog;
DE            Short=hNup188;
GN   Name=NUP188; Synonyms=KIAA0169;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU1M_HUMAN              Reviewed;         318 AA.
AC   P03886; C0JKH6; Q37523;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 1;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 1;
GN   Name=MT-ND1; Synonyms=MTND1, NADH1, ND1;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NU205_HUMAN             Reviewed;        2012 AA.
AC   Q92621; A6H8X3; Q86YC1;
DE   RecName: Full=Nuclear pore complex protein Nup205;
DE   AltName: Full=205 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup205;
GN   Name=NUP205; Synonyms=C7orf14, KIAA0225;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IMP:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; TAS:UniProtKB.
DR   GO; GO:0000059; P:protein import into nucleus, docking; TAS:UniProtKB.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU214_HUMAN             Reviewed;        2090 AA.
AC   P35658; A6NFQ0; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3;
DE   RecName: Full=Nuclear pore complex protein Nup214;
DE   AltName: Full=214 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup214;
DE   AltName: Full=Protein CAN;
GN   Name=NUP214; Synonyms=CAIN, CAN, KIAA0023;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006611; P:protein export from nucleus; IMP:MGI.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NU2M_HUMAN              Reviewed;         347 AA.
AC   P03891; Q34769; Q9TGI0; Q9TGI1; Q9TGI2; Q9TGI3; Q9TGI4;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 2;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 2;
GN   Name=MT-ND2; Synonyms=MTND2, NADH2, ND2;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NU3M_HUMAN              Reviewed;         115 AA.
AC   P03897;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 3;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 3;
GN   Name=MT-ND3; Synonyms=MTND3, NADH3, ND3;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NU4LM_HUMAN             Reviewed;          98 AA.
AC   P03901;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 4L;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 4L;
GN   Name=MT-ND4L; Synonyms=MTND4L, NADH4L, ND4L;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NU4M_HUMAN              Reviewed;         459 AA.
AC   P03905; Q6RL39; Q6RQN9; Q8HNR8;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 4;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 4;
GN   Name=MT-ND4; Synonyms=MTND4, NADH4, ND4;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NU5M_HUMAN              Reviewed;         603 AA.
AC   P03915; Q34773; Q8WCY3;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 5;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 5;
GN   Name=MT-ND5; Synonyms=MTND5, NADH5, ND5;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NU6M_HUMAN              Reviewed;         174 AA.
AC   P03923; Q34774; Q8HG30;
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 6;
DE            EC=1.6.5.3;
DE   AltName: Full=NADH dehydrogenase subunit 6;
GN   Name=MT-ND6; Synonyms=MTND6, NADH6, ND6;
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUA4L_HUMAN             Reviewed;          87 AA.
AC   Q9NRX3; Q6IAH9;
DE   RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2;
DE   AltName: Full=NADH-ubiquinone oxidoreductase MLRQ subunit homolog;
DE            Short=NUOMS;
GN   Name=NDUFA4L2;
//
ID   NUAK1_HUMAN             Reviewed;         661 AA.
AC   O60285; A7MD39; Q96KA8;
DE   RecName: Full=NUAK family SNF1-like kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=AMPK-related protein kinase 5;
DE            Short=ARK5;
DE   AltName: Full=Omphalocele kinase 1;
GN   Name=NUAK1; Synonyms=ARK5, KIAA0537, OMPHK1;
DR   GuidetoPHARMACOLOGY; 2129; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.
DR   GO; GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.
//
ID   NUAK2_HUMAN             Reviewed;         628 AA.
AC   Q9H093;
DE   RecName: Full=NUAK family SNF1-like kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=Omphalocele kinase 2;
DE   AltName: Full=SNF1/AMP kinase-related kinase;
DE            Short=SNARK;
GN   Name=NUAK2; Synonyms=OMPHK2, SNARK;
DR   GuidetoPHARMACOLOGY; 2130; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   NUB1_HUMAN              Reviewed;         615 AA.
AC   Q9Y5A7; O95422; Q75MR9; Q8IX22; Q9BXR2;
DE   RecName: Full=NEDD8 ultimate buster 1;
DE   AltName: Full=Negative regulator of ubiquitin-like proteins 1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-18;
GN   Name=NUB1; Synonyms=NYREN18;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   NUBP1_HUMAN             Reviewed;         320 AA.
AC   P53384; Q32M30; Q498A9; Q53FS7;
DE   RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP1;
DE   AltName: Full=Nucleotide-binding protein 1;
DE            Short=NBP 1;
GN   Name=NUBP1; Synonyms=NBP, NBP1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IMP:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IMP:UniProtKB.
DR   GO; GO:0010826; P:negative regulation of centrosome duplication; IEA:Ensembl.
DR   GO; GO:0072697; P:protein localization to cell cortex; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUBP2_HUMAN             Reviewed;         271 AA.
AC   Q9Y5Y2; D3DU80; Q9NWB2;
DE   RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2;
DE   AltName: Full=Nucleotide-binding protein 2;
DE            Short=NBP 2;
GN   Name=NUBP2;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUBPL_HUMAN             Reviewed;         319 AA.
AC   Q8TB37; B4DHZ1; Q86TZ4; Q9H9M2;
DE   RecName: Full=Iron-sulfur protein NUBPL;
DE   AltName: Full=IND1 homolog;
DE   AltName: Full=Nucleotide-binding protein-like;
DE   AltName: Full=huInd1;
DE   Flags: Precursor;
GN   Name=NUBPL; Synonyms=C14orf127;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:UniProtKB.
//
ID   NUCB1_HUMAN             Reviewed;         461 AA.
AC   Q02818; B2RD64; Q15838; Q7Z4J7; Q9BUR1;
DE   RecName: Full=Nucleobindin-1;
DE   AltName: Full=CALNUC;
DE   Flags: Precursor;
GN   Name=NUCB1; Synonyms=NUC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NUCB2_HUMAN             Reviewed;         420 AA.
AC   P80303; A8K642; D3DQX5; Q8NFT5;
DE   RecName: Full=Nucleobindin-2;
DE   AltName: Full=DNA-binding protein NEFA;
DE   AltName: Full=Gastric cancer antigen Zg4;
DE   AltName: Full=Prepronesfatin;
DE   Contains:
DE     RecName: Full=Nesfatin-1;
DE   Flags: Precursor;
GN   Name=NUCB2; Synonyms=NEFA;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NUCG_HUMAN              Reviewed;         297 AA.
AC   Q14249; Q5T281; Q9BSP2;
DE   RecName: Full=Endonuclease G, mitochondrial;
DE            Short=Endo G;
DE            EC=3.1.30.-;
DE   Flags: Precursor;
GN   Name=ENDOG;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IBA:RefGenome.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IBA:RefGenome.
DR   GO; GO:0006310; P:DNA recombination; TAS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
//
ID   NUCKS_HUMAN             Reviewed;         243 AA.
AC   Q9H1E3; Q54AC0; Q5PXE7; Q9H1D6; Q9H723;
DE   RecName: Full=Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1;
DE   AltName: Full=P1;
GN   Name=NUCKS1; Synonyms=NUCKS; ORFNames=JC7;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NUCL_HUMAN              Reviewed;         710 AA.
AC   P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1;
DE   RecName: Full=Nucleolin;
DE   AltName: Full=Protein C23;
GN   Name=NCL;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:1901838; P:positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:UniProt.
//
ID   NUD10_HUMAN             Reviewed;         164 AA.
AC   Q8NFP7; A8K7D7; D3DX69; Q86VK1; Q86VR0;
DE   RecName: Full=Diphosphoinositol polyphosphate phosphohydrolase 3-alpha;
DE            Short=DIPP-3-alpha;
DE            Short=DIPP3-alpha;
DE            Short=hDIPP3alpha;
DE            EC=3.6.1.52;
DE   AltName: Full=Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha;
DE   AltName: Full=Diadenosine hexaphosphate hydrolase (AMP-forming);
DE            EC=3.6.1.60;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 10;
DE            Short=Nudix motif 10;
DE   AltName: Full=hAps2;
GN   Name=NUDT10; Synonyms=APS2, DIPP3A;
DR   GO; GO:0008486; F:diphosphoinositol-polyphosphate diphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0052840; F:inositol diphosphate tetrakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052846; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052847; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052843; F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052848; F:inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052844; F:inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052845; F:inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUD11_HUMAN             Reviewed;         164 AA.
AC   Q96G61; Q9NVN0;
DE   RecName: Full=Diphosphoinositol polyphosphate phosphohydrolase 3-beta;
DE            Short=DIPP-3-beta;
DE            Short=DIPP3-beta;
DE            Short=hDIPP3beta;
DE            EC=3.6.1.52;
DE   AltName: Full=Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta;
DE   AltName: Full=Diadenosine hexaphosphate hydrolase (AMP-forming);
DE            EC=3.6.1.60;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 11;
DE            Short=Nudix motif 11;
DE   AltName: Full=hAps1;
GN   Name=NUDT11; Synonyms=APS1, DIPP3B;
DR   GO; GO:0008486; F:diphosphoinositol-polyphosphate diphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0052840; F:inositol diphosphate tetrakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052846; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052847; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052843; F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052848; F:inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052844; F:inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052845; F:inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUD13_HUMAN             Reviewed;         352 AA.
AC   Q86X67; B4DV90; O95650; Q5SQM4; Q5SQM5; Q9Y3X2;
DE   RecName: Full=Nucleoside diphosphate-linked moiety X motif 13;
DE            Short=Nudix motif 13;
DE            EC=3.-.-.-;
DE   AltName: Full=Protein KiSS-16;
GN   Name=NUDT13;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
//
ID   NUD12_HUMAN             Reviewed;         462 AA.
AC   Q9BQG2; B3KUW2; Q8TAL7;
DE   RecName: Full=Peroxisomal NADH pyrophosphatase NUDT12;
DE            EC=3.6.1.22;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 12;
DE            Short=Nudix motif 12;
GN   Name=NUDT12;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000210; F:NAD+ diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0035529; F:NADH pyrophosphatase activity; IDA:UniProtKB.
DR   GO; GO:0019677; P:NAD catabolic process; IDA:UniProtKB.
DR   GO; GO:0006742; P:NADP catabolic process; IDA:UniProtKB.
//
ID   NUD14_HUMAN             Reviewed;         222 AA.
AC   O95848; Q86SJ8;
DE   RecName: Full=Uridine diphosphate glucose pyrophosphatase;
DE            Short=UDPG pyrophosphatase;
DE            Short=UGPPase;
DE            EC=3.6.1.45;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 14;
DE            Short=Nudix motif 14;
GN   Name=NUDT14; Synonyms=UGPP;
DR   GO; GO:0047631; F:ADP-ribose diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008768; F:UDP-sugar diphosphatase activity; IEA:UniProtKB-EC.
//
ID   NUD15_HUMAN             Reviewed;         164 AA.
AC   Q9NV35; A2RUR6; Q32Q27; Q6P2C9;
DE   RecName: Full=Probable 8-oxo-dGTP diphosphatase NUDT15;
DE            Short=8-oxo-dGTPase NUDT15;
DE            EC=3.6.1.55;
DE   AltName: Full=7,8-dihydro-8-oxoguanine-triphosphatase NUDT15;
DE   AltName: Full=MutT homolog 2;
DE            Short=MTH2;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 15;
DE            Short=Nudix motif 15;
GN   Name=NUDT15; Synonyms=MTH2;
DR   GO; GO:0035539; F:8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008413; F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006203; P:dGTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUD16_HUMAN             Reviewed;         195 AA.
AC   Q96DE0; B4E3B4; E9PED4; F5GYJ1; Q96N82;
DE   RecName: Full=U8 snoRNA-decapping enzyme;
DE            EC=3.6.1.62;
DE   AltName: Full=IDP phosphatase;
DE            Short=IDPase;
DE            EC=3.6.1.-;
DE   AltName: Full=Inosine diphosphate phosphatase;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 16;
DE            Short=Nudix motif 16;
DE   AltName: Full=U8 snoRNA-binding protein H29K;
DE   AltName: Full=m7GpppN-mRNA hydrolase;
GN   Name=NUDT16;
DR   GO; GO:0050897; F:cobalt ion binding; IDA:UniProtKB.
DR   GO; GO:0097383; F:dIDP diphosphatase activity; EXP:Reactome.
DR   GO; GO:0035870; F:dITP diphosphatase activity; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0090450; F:inosine-diphosphatase activity; EXP:Reactome.
DR   GO; GO:1901641; F:ITP binding; IDA:UniProtKB.
DR   GO; GO:0050072; F:m7G(5')pppN diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0098519; F:nucleotide phosphatase activity, acting on free nucleotides; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030515; F:snoRNA binding; IDA:UniProtKB.
DR   GO; GO:1901640; F:XTP binding; IDA:UniProtKB.
DR   GO; GO:0006382; P:adenosine to inosine editing; IMP:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0035863; P:dITP catabolic process; ISS:UniProtKB.
DR   GO; GO:0046709; P:IDP catabolic process; IDA:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:2000233; P:negative regulation of rRNA processing; ISS:UniProtKB.
DR   GO; GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0090068; P:positive regulation of cell cycle process; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:2000781; P:positive regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016077; P:snoRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:1901639; P:XDP catabolic process; IDA:UniProtKB.
//
ID   NUD17_HUMAN             Reviewed;         328 AA.
AC   P0C025;
DE   RecName: Full=Nucleoside diphosphate-linked moiety X motif 17;
DE            Short=Nudix motif 17;
DE            EC=3.6.1.-;
GN   Name=NUDT17;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NUD18_HUMAN             Reviewed;         323 AA.
AC   Q6ZVK8; Q8IZ75; Q9H687;
DE   RecName: Full=8-oxo-dGDP phosphatase NUDT18;
DE            EC=3.6.1.58;
DE   AltName: Full=2-hydroxy-dADP phosphatase;
DE   AltName: Full=7,8-dihydro-8-oxoguanine phosphatase;
DE   AltName: Full=MutT homolog 3;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 18;
DE            Short=Nudix motif 18;
GN   Name=NUDT18; Synonyms=MTH3;
DR   GO; GO:0044717; F:8-hydroxy-dADP phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0044715; F:8-oxo-dGDP phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0044716; F:8-oxo-GDP phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046057; P:dADP catabolic process; IDA:UniProtKB.
DR   GO; GO:0046067; P:dGDP catabolic process; IDA:UniProtKB.
DR   GO; GO:0046712; P:GDP catabolic process; IDA:UniProtKB.
DR   GO; GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUD19_HUMAN             Reviewed;         375 AA.
AC   A8MXV4;
DE   RecName: Full=Nucleoside diphosphate-linked moiety X motif 19, mitochondrial;
DE            Short=Nudix motif 19;
DE            EC=3.6.1.-;
DE   Flags: Precursor;
GN   Name=NUDT19;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
//
ID   NUD22_HUMAN             Reviewed;         303 AA.
AC   Q9BRQ3; C9JY06; Q71RD5;
DE   RecName: Full=Nucleoside diphosphate-linked moiety X motif 22;
DE            Short=Nudix motif 22;
GN   Name=NUDT22; ORFNames=PP11246;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
//
ID   NUDC2_HUMAN             Reviewed;         157 AA.
AC   Q8WVJ2; B2R4V0;
DE   RecName: Full=NudC domain-containing protein 2;
GN   Name=NUDCD2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   NUDC3_HUMAN             Reviewed;         361 AA.
AC   Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4;
DE   RecName: Full=NudC domain-containing protein 3;
GN   Name=NUDCD3; Synonyms=KIAA1068;
//
ID   NUDC1_HUMAN             Reviewed;         583 AA.
AC   Q96RS6; B4DVX6; Q4G130; Q8NDQ5; Q8NG18; Q96SI4; Q9BVR5;
DE   RecName: Full=NudC domain-containing protein 1;
DE   AltName: Full=Chronic myelogenous leukemia tumor antigen 66;
DE   AltName: Full=Tumor antigen CML66;
GN   Name=NUDCD1; Synonyms=CML66;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   NUDC_HUMAN              Reviewed;         331 AA.
AC   Q9Y266; Q5QP31; Q5QP35; Q9H0N2; Q9Y2B6;
DE   RecName: Full=Nuclear migration protein nudC;
DE   AltName: Full=Nuclear distribution protein C homolog;
GN   Name=NUDC;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   NUDT3_HUMAN             Reviewed;         172 AA.
AC   O95989; B2R8N4;
DE   RecName: Full=Diphosphoinositol polyphosphate phosphohydrolase 1;
DE            Short=DIPP-1;
DE            EC=3.6.1.52;
DE   AltName: Full=Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1;
DE            EC=3.6.1.-;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 3;
DE            Short=Nudix motif 3;
GN   Name=NUDT3; Synonyms=DIPP, DIPP1;
DR   GO; GO:0008486; F:diphosphoinositol-polyphosphate diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0052840; F:inositol diphosphate tetrakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052846; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052847; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052843; F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052848; F:inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052844; F:inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052845; F:inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0015961; P:diadenosine polyphosphate catabolic process; TAS:ProtInc.
DR   GO; GO:0071544; P:diphosphoinositol polyphosphate catabolic process; IDA:UniProtKB.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUDT4_HUMAN             Reviewed;         180 AA.
AC   Q9NZJ9; B7Z916; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZK0;
AC   Q9NZK1;
DE   RecName: Full=Diphosphoinositol polyphosphate phosphohydrolase 2;
DE            Short=DIPP-2;
DE            EC=3.6.1.52;
DE   AltName: Full=Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2;
DE            EC=3.6.1.-;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 4;
DE            Short=Nudix motif 4;
GN   Name=NUDT4; Synonyms=DIPP2, KIAA0487; ORFNames=HDCMB47P;
DR   GO; GO:0008486; F:diphosphoinositol-polyphosphate diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0052840; F:inositol diphosphate tetrakisphosphate diphosphatase activity; TAS:Reactome.
DR   GO; GO:0052846; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052847; F:inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052843; F:inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052848; F:inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052844; F:inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052845; F:inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0009187; P:cyclic nucleotide metabolic process; TAS:ProtInc.
DR   GO; GO:0019935; P:cyclic-nucleotide-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0046907; P:intracellular transport; TAS:UniProtKB.
DR   GO; GO:0046831; P:regulation of RNA export from nucleus; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUDT5_HUMAN             Reviewed;         219 AA.
AC   Q9UKK9; A8K516; Q6IAG0; Q9UH49;
DE   RecName: Full=ADP-sugar pyrophosphatase;
DE            EC=3.6.1.13;
DE   AltName: Full=8-oxo-dGDP phosphatase;
DE            EC=3.6.1.58;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 5;
DE            Short=Nudix motif 5;
DE   AltName: Full=YSA1H;
GN   Name=NUDT5; ORFNames=HSPC115;
DR   GO; GO:0047631; F:ADP-ribose diphosphatase activity; EXP:Reactome.
DR   GO; GO:0019144; F:ADP-sugar diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0017110; F:nucleoside-diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0019303; P:D-ribose catabolic process; NAS:UniProtKB.
DR   GO; GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009117; P:nucleotide metabolic process; NAS:ProtInc.
DR   GO; GO:0009191; P:ribonucleoside diphosphate catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUDT7_HUMAN             Reviewed;         238 AA.
AC   P0C024; B4DLE5; H3BUB8;
DE   RecName: Full=Peroxisomal coenzyme A diphosphatase NUDT7;
DE            EC=3.6.1.-;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 7;
DE            Short=Nudix motif 7;
GN   Name=NUDT7;
DR   GO; GO:0003986; F:acetyl-CoA hydrolase activity; ISS:UniProtKB.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0046356; P:acetyl-CoA catabolic process; ISS:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0015938; P:coenzyme A catabolic process; ISS:UniProtKB.
DR   GO; GO:0009132; P:nucleoside diphosphate metabolic process; IEA:InterPro.
//
ID   NUDT6_HUMAN             Reviewed;         316 AA.
AC   P53370; A8K756; O95097; Q9UQD9;
DE   RecName: Full=Nucleoside diphosphate-linked moiety X motif 6;
DE            Short=Nudix motif 6;
DE            EC=3.6.1.-;
DE   AltName: Full=Antisense basic fibroblast growth factor;
DE   AltName: Full=Protein GFG;
GN   Name=NUDT6; Synonyms=FGF2AS;
DR   GO; GO:0008083; F:growth factor activity; TAS:UniProtKB.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   NUDT8_HUMAN             Reviewed;         236 AA.
AC   Q8WV74; Q6ZW59;
DE   RecName: Full=Nucleoside diphosphate-linked moiety X motif 8, mitochondrial;
DE            Short=Nudix motif 8;
DE            EC=3.6.1.-;
DE   Flags: Precursor;
GN   Name=NUDT8;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   NUDT9_HUMAN             Reviewed;         350 AA.
AC   Q9BW91; Q8NBN1; Q8NCB9; Q8NG25;
DE   RecName: Full=ADP-ribose pyrophosphatase, mitochondrial;
DE            EC=3.6.1.13;
DE   AltName: Full=ADP-ribose diphosphatase;
DE   AltName: Full=ADP-ribose phosphohydrolase;
DE   AltName: Full=Adenosine diphosphoribose pyrophosphatase;
DE            Short=ADPR-PPase;
DE   AltName: Full=Nucleoside diphosphate-linked moiety X motif 9;
DE            Short=Nudix motif 9;
DE   Flags: Precursor;
GN   Name=NUDT9; Synonyms=NUDT10; ORFNames=PSEC0099, UNQ3012/PRO9771;
DR   GO; GO:0043262; F:adenosine-diphosphatase activity; IEA:Ensembl.
DR   GO; GO:0047631; F:ADP-ribose diphosphatase activity; EXP:Reactome.
DR   GO; GO:0019144; F:ADP-sugar diphosphatase activity; NAS:UniProtKB.
DR   GO; GO:0046032; P:ADP catabolic process; IEA:Ensembl.
DR   GO; GO:0046709; P:IDP catabolic process; IEA:Ensembl.
DR   GO; GO:0034656; P:nucleobase-containing small molecule catabolic process; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   NUF2_HUMAN              Reviewed;         464 AA.
AC   Q9BZD4; Q8WU69; Q96HJ4; Q96Q78;
DE   RecName: Full=Kinetochore protein Nuf2;
DE            Short=hNuf2;
DE            Short=hNuf2R;
DE            Short=hsNuf2;
DE   AltName: Full=Cell division cycle-associated protein 1;
GN   Name=NUF2; Synonyms=CDCA1, NUF2R;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007059; P:chromosome segregation; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   NUFP2_HUMAN             Reviewed;         695 AA.
AC   Q7Z417; Q9P2M5;
DE   RecName: Full=Nuclear fragile X mental retardation-interacting protein 2;
DE   AltName: Full=82 kDa FMRP-interacting protein;
DE            Short=82-FIP;
DE   AltName: Full=Cell proliferation-inducing gene 1 protein;
DE   AltName: Full=FMRP-interacting protein 2;
GN   Name=NUFIP2; Synonyms=KIAA1321; ORFNames=PIG1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0003723; F:RNA binding; IDA:HGNC.
//
ID   NUFP1_HUMAN             Reviewed;         495 AA.
AC   Q9UHK0; Q8WVM5; Q96SG1;
DE   RecName: Full=Nuclear fragile X mental retardation-interacting protein 1;
DE   AltName: Full=Nuclear FMRP-interacting protein 1;
GN   Name=NUFIP1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IPI:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; IDA:HGNC.
DR   GO; GO:0000492; P:box C/D snoRNP assembly; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:HGNC.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   NUMA1_HUMAN             Reviewed;        2115 AA.
AC   Q14980; H0YH75; Q14981; Q9BTE9;
DE   RecName: Full=Nuclear mitotic apparatus protein 1;
DE            Short=NuMA protein;
DE   AltName: Full=SP-H antigen;
GN   Name=NUMA1; Synonyms=NUMA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000090; P:mitotic anaphase; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006997; P:nucleus organization; TAS:ProtInc.
//
ID   NUMBL_HUMAN             Reviewed;         609 AA.
AC   Q9Y6R0; Q7Z4J9;
DE   RecName: Full=Numb-like protein;
DE   AltName: Full=Numb-related protein;
DE            Short=Numb-R;
GN   Name=NUMBL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0021670; P:lateral ventricle development; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0021849; P:neuroblast division in subventricular zone; ISS:UniProtKB.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0019538; P:protein metabolic process; IDA:UniProtKB.
//
ID   NUMB_HUMAN              Reviewed;         651 AA.
AC   P49757; B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; Q6NUQ7;
AC   Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4;
DE   RecName: Full=Protein numb homolog;
DE            Short=h-Numb;
DE   AltName: Full=Protein S171;
GN   Name=NUMB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034332; P:adherens junction organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0021670; P:lateral ventricle development; ISS:UniProtKB.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0021849; P:neuroblast division in subventricular zone; ISS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0030862; P:positive regulation of polarized epithelial cell differentiation; IEA:Ensembl.
//
ID   NUP37_HUMAN             Reviewed;         326 AA.
AC   Q8NFH4; Q9H644;
DE   RecName: Full=Nucleoporin Nup37;
DE            Short=p37;
DE   AltName: Full=Nup107-160 subcomplex subunit Nup37;
GN   Name=NUP37;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP43_HUMAN             Reviewed;         380 AA.
AC   Q8NFH3; Q9H8S0;
DE   RecName: Full=Nucleoporin Nup43;
DE   AltName: Full=Nup107-160 subcomplex subunit Nup43;
DE   AltName: Full=p42;
GN   Name=NUP43;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP50_HUMAN             Reviewed;         468 AA.
AC   Q9UKX7; B1AHA4; B2RB15; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5;
DE   RecName: Full=Nuclear pore complex protein Nup50;
DE   AltName: Full=50 kDa nucleoporin;
DE   AltName: Full=Nuclear pore-associated protein 60 kDa-like;
DE   AltName: Full=Nucleoporin Nup50;
GN   Name=NUP50; Synonyms=NPAP60L; ORFNames=PRO1146;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP53_HUMAN             Reviewed;         326 AA.
AC   Q8NFH5; Q4ZFZ9; Q53S95; Q8TDJ1;
DE   RecName: Full=Nucleoporin NUP53;
DE   AltName: Full=35 kDa nucleoporin;
DE   AltName: Full=Mitotic phosphoprotein 44;
DE            Short=MP-44;
DE   AltName: Full=Nuclear pore complex protein Nup53;
DE   AltName: Full=Nucleoporin Nup35;
GN   Name=NUP35; Synonyms=MP44, NUP53;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP54_HUMAN             Reviewed;         507 AA.
AC   Q7Z3B4; B2RCK7; B4DT35; Q96EA7; Q9NVL5; Q9P0I1;
DE   RecName: Full=Nucleoporin p54;
DE   AltName: Full=54 kDa nucleoporin;
GN   Name=NUP54;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP62_HUMAN             Reviewed;         522 AA.
AC   P37198; B3KWU5; Q503A4; Q6GTM2; Q96C43; Q9NSL1;
DE   RecName: Full=Nuclear pore glycoprotein p62;
DE   AltName: Full=62 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup62;
GN   Name=NUP62;
DR   GO; GO:0003682; F:chromatin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IMP:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IDA:UniProtKB.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; NAS:GOC.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0046578; P:regulation of Ras protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP85_HUMAN             Reviewed;         656 AA.
AC   Q9BW27; Q8NDI4; Q9H9U1;
DE   RecName: Full=Nuclear pore complex protein Nup85;
DE   AltName: Full=85 kDa nucleoporin;
DE   AltName: Full=FROUNT;
DE   AltName: Full=Nucleoporin Nup75;
DE   AltName: Full=Nucleoporin Nup85;
DE   AltName: Full=Pericentrin-1;
GN   Name=NUP85; Synonyms=NUP75, PCNT1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0048246; P:macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP88_HUMAN             Reviewed;         741 AA.
AC   Q99567; D3DTM2; Q9BWE5;
DE   RecName: Full=Nuclear pore complex protein Nup88;
DE   AltName: Full=88 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup88;
GN   Name=NUP88;
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP93_HUMAN             Reviewed;         819 AA.
AC   Q8N1F7; B3KPQ8; Q14705;
DE   RecName: Full=Nuclear pore complex protein Nup93;
DE   AltName: Full=93 kDa nucleoporin;
DE   AltName: Full=Nucleoporin Nup93;
GN   Name=NUP93; Synonyms=KIAA0095;
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IMP:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUP98_HUMAN             Reviewed;        1817 AA.
AC   P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0;
AC   Q9Y6J4; Q9Y6J5;
DE   RecName: Full=Nuclear pore complex protein Nup98-Nup96;
DE   Contains:
DE     RecName: Full=Nuclear pore complex protein Nup98;
DE     AltName: Full=98 kDa nucleoporin;
DE     AltName: Full=Nucleoporin Nup98;
DE              Short=Nup98;
DE   Contains:
DE     RecName: Full=Nuclear pore complex protein Nup96;
DE     AltName: Full=96 kDa nucleoporin;
DE     AltName: Full=Nucleoporin Nup96;
DE              Short=Nup96;
DE   Flags: Precursor;
GN   Name=NUP98; Synonyms=ADAR2;
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IMP:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0051292; P:nuclear pore complex assembly; IMP:UniProtKB.
DR   GO; GO:0006999; P:nuclear pore organization; NAS:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; TAS:UniProtKB.
DR   GO; GO:0000059; P:protein import into nucleus, docking; NAS:UniProtKB.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUPL1_HUMAN             Reviewed;         599 AA.
AC   Q9BVL2; A6NI12; B4DZJ1; O43160; Q5JRG2; Q5JRG5;
DE   RecName: Full=Nucleoporin p58/p45;
DE   AltName: Full=Nucleoporin-like protein 1;
GN   Name=NUPL1; Synonyms=KIAA0410;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUPL2_HUMAN             Reviewed;         423 AA.
AC   O15504; A4D143; B4DP42; Q49AE7; Q9BS49;
DE   RecName: Full=Nucleoporin-like protein 2;
DE   AltName: Full=NLP-1;
DE   AltName: Full=NUP42 homolog;
DE   AltName: Full=Nucleoporin hCG1;
GN   Name=NUPL2; Synonyms=CG1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006611; P:protein export from nucleus; TAS:ProtInc.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   NUPR1_HUMAN             Reviewed;          82 AA.
AC   O60356; B2R5C4; O60357; Q6FGG3;
DE   RecName: Full=Nuclear protein 1;
DE   AltName: Full=Candidate of metastasis 1;
DE   AltName: Full=Protein p8;
GN   Name=NUPR1; Synonyms=COM1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0031401; P:positive regulation of protein modification process; IEA:Ensembl.
DR   GO; GO:0006473; P:protein acetylation; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:2000194; P:regulation of female gonad development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   NUR1L_HUMAN             Reviewed;          97 AA.
AC   A6NF83;
DE   RecName: Full=Nuclear transcriptional regulator 1-like protein;
GN   Name=NUPR1L;
//
ID   NUSAP_HUMAN             Reviewed;         441 AA.
AC   Q9BXS6; B4DDF1; E7ERR5; J3KN21; Q53GW2; Q8TBT4; Q96E58; Q96FJ1;
AC   Q9GZM9; Q9NZ85; Q9UI70;
DE   RecName: Full=Nucleolar and spindle-associated protein 1;
DE            Short=NuSAP;
GN   Name=NUSAP1; Synonyms=ANKT; ORFNames=BM-037, PRO0310;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0040001; P:establishment of mitotic spindle localization; IDA:MGI.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:MGI.
DR   GO; GO:0000281; P:mitotic cytokinesis; IDA:MGI.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IDA:MGI.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:MGI.
//
ID   NUTM1_HUMAN             Reviewed;        1132 AA.
AC   Q86Y26; Q86YS8; Q8N7F2; Q9NTB3;
DE   RecName: Full=NUT family member 1;
DE   AltName: Full=Nuclear protein in testis;
GN   Name=NUTM1; Synonyms=C15orf55, NUT;
//
ID   NVL_HUMAN               Reviewed;         856 AA.
AC   O15381; B4DMC4; B4DP98; Q96EM7;
DE   RecName: Full=Nuclear valosin-containing protein-like;
DE            Short=NVLp;
DE            Short=Nuclear VCP-like protein;
GN   Name=NVL;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   NWD1_HUMAN              Reviewed;        1564 AA.
AC   Q149M9; C9J021; Q68CT3;
DE   RecName: Full=NACHT and WD repeat domain-containing protein 1;
GN   Name=NWD1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   NWD2_HUMAN              Reviewed;        1742 AA.
AC   Q9ULI1; A8MRU1;
DE   RecName: Full=NACHT and WD repeat domain-containing protein 2;
DE   AltName: Full=Leucine-rich repeat and WD repeat-containing protein KIAA1239;
GN   Name=NWD2; Synonyms=KIAA1239;
//
ID   NXF1_HUMAN              Reviewed;         619 AA.
AC   Q9UBU9; B4E269; Q99799; Q9UQL2;
DE   RecName: Full=Nuclear RNA export factor 1;
DE   AltName: Full=Tip-associated protein;
DE   AltName: Full=Tip-associating protein;
DE   AltName: Full=mRNA export factor TAP;
GN   Name=NXF1; Synonyms=TAP;
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   NXF2_HUMAN              Reviewed;         626 AA.
AC   Q9GZY0; Q9BXU4; Q9NSS1; Q9NX66;
DE   RecName: Full=Nuclear RNA export factor 2;
DE   AltName: Full=Cancer/testis antigen 39;
DE            Short=CT39;
DE   AltName: Full=TAP-like protein 2;
DE            Short=TAPL-2;
GN   Name=NXF2; Synonyms=TAPL2;
GN   and
GN   Name=NXF2B;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; ISS:UniProtKB.
DR   GO; GO:0050658; P:RNA transport; ISS:UniProtKB.
//
ID   NXF5_HUMAN              Reviewed;         397 AA.
AC   Q9H1B4; A2RRM0; B1AV82; B1AV83; B1AV84; B1AV85; Q9H1B0; Q9H1B1;
AC   Q9H1B2; Q9H1B3;
DE   RecName: Full=Nuclear RNA export factor 5;
DE   AltName: Full=TAP-like protein 1;
DE            Short=TAPL-1;
GN   Name=NXF5; Synonyms=TAPL1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEP:UniProtKB.
DR   GO; GO:0050658; P:RNA transport; IDA:UniProtKB.
//
ID   NXF3_HUMAN              Reviewed;         531 AA.
AC   Q9H4D5; Q5H9I1; Q9H1A9;
DE   RecName: Full=Nuclear RNA export factor 3;
DE   AltName: Full=TAP-like protein 3;
DE            Short=TAPL-3;
GN   Name=NXF3; Synonyms=TAPL3;
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:Ensembl.
//
ID   NXNL1_HUMAN             Reviewed;         212 AA.
AC   Q96CM4; Q0QD37;
DE   RecName: Full=Nucleoredoxin-like protein 1;
DE   AltName: Full=Thioredoxin-like protein 6;
GN   Name=NXNL1; Synonyms=TXNL6;
//
ID   NXN_HUMAN               Reviewed;         435 AA.
AC   Q6DKJ4; B4DXQ0; D3DTH2; Q3SWW6; Q6P3U6; Q7L4C6; Q9H9Q1;
DE   RecName: Full=Nucleoredoxin;
DE            EC=1.8.1.8;
GN   Name=NXN; Synonyms=NRX;
DR   GO; GO:0047134; F:protein-disulfide reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase activity; IEA:Ensembl.
DR   GO; GO:0072358; P:cardiovascular system development; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   NXNL2_HUMAN             Reviewed;         156 AA.
AC   Q5VZ03; B1AMD0; Q8TBG6;
DE   RecName: Full=Nucleoredoxin-like protein 2;
DE   AltName: Full=Rod-derived cone viability factor 2;
DE            Short=RdCVF2;
GN   Name=NXNL2; Synonyms=C9orf121;
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:Ensembl.
//
ID   NXP20_HUMAN             Reviewed;         563 AA.
AC   Q8IWE2; A8K9W6; Q9BVL6;
DE   RecName: Full=Protein NOXP20;
DE   AltName: Full=Nervous system overexpressed protein 20;
DE   AltName: Full=Protein FAM114A1;
GN   Name=FAM114A1; Synonyms=NOXP20;
//
ID   NXPE2_HUMAN             Reviewed;         559 AA.
AC   Q96DL1; Q2NKI8;
DE   RecName: Full=NXPE family member 2;
DE   AltName: Full=Protein FAM55B;
GN   Name=NXPE2; Synonyms=FAM55B;
//
ID   NXPE1_HUMAN             Reviewed;         547 AA.
AC   Q8N323; B0YJ13;
DE   RecName: Full=NXPE family member 1;
DE   AltName: Full=Protein FAM55A;
DE   Flags: Precursor;
GN   Name=NXPE1; Synonyms=FAM55A;
//
ID   NXPE3_HUMAN             Reviewed;         559 AA.
AC   Q969Y0; A8K0X4; D3DN53; Q7Z2S8;
DE   RecName: Full=NXPE family member 3;
DE   AltName: Full=Protein FAM55C;
DE   Flags: Precursor;
GN   Name=NXPE3; Synonyms=FAM55C; ORFNames=MSTP115, UNQ5791/PRO19596;
//
ID   NXPE4_HUMAN             Reviewed;         544 AA.
AC   Q6UWF7; Q6QDB4; Q9NXP5;
DE   RecName: Full=NXPE family member 4;
DE   AltName: Full=Protein FAM55D;
DE   Flags: Precursor;
GN   Name=NXPE4; Synonyms=C11orf33, FAM55D; ORFNames=UNQ3018/PRO9799;
//
ID   NXPH1_HUMAN             Reviewed;         271 AA.
AC   P58417; Q8NB31;
DE   RecName: Full=Neurexophilin-1;
DE   Flags: Precursor;
GN   Name=NXPH1; Synonyms=NPH1; ORFNames=Nbla00697;
//
ID   NXPH2_HUMAN             Reviewed;         264 AA.
AC   O95156; B7WP24; Q494R1; Q75QC3;
DE   RecName: Full=Neurexophilin-2;
DE   Flags: Precursor;
GN   Name=NXPH2; Synonyms=NPH2;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   NXPH3_HUMAN             Reviewed;         252 AA.
AC   O95157; Q8NDC3; Q8TBF6; Q9ULR1;
DE   RecName: Full=Neurexophilin-3;
DE   Flags: Precursor;
GN   Name=NXPH3; Synonyms=KIAA1159, NPH3; ORFNames=UNQ687/PRO1327;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   NXRD1_HUMAN             Reviewed;         359 AA.
AC   Q6NXP6; B3KQ47; O95435;
DE   RecName: Full=NADP-dependent oxidoreductase domain-containing protein 1;
DE            EC=1.-.-.-;
DE   AltName: Full=Pyrroline-5-carboxylate reductase-like protein C14orf148;
GN   Name=NOXRED1; Synonyms=C14orf148;
DR   GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:InterPro.
DR   GO; GO:0006561; P:proline biosynthetic process; IEA:InterPro.
//
ID   NXPH4_HUMAN             Reviewed;         308 AA.
AC   O95158; A8K4I4; Q7Z6L3; Q8N462;
DE   RecName: Full=Neurexophilin-4;
DE   Flags: Precursor;
GN   Name=NXPH4; Synonyms=NPH4; ORFNames=UNQ1928/PRO4403;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   NXT1_HUMAN              Reviewed;         140 AA.
AC   Q9UKK6;
DE   RecName: Full=NTF2-related export protein 1;
DE   AltName: Full=Protein p15;
GN   Name=NXT1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0006405; P:RNA export from nucleus; IEA:Ensembl.
//
ID   NXT2_HUMAN              Reviewed;         142 AA.
AC   Q9NPJ8; D3DUY1; Q0VAN8; Q5JYV5; Q5JYV6; Q5JYV7; Q9H8U0; Q9NQ64;
AC   Q9NRL7; Q9Y3M4; Q9Y3M5;
DE   RecName: Full=NTF2-related export protein 2;
DE   AltName: Full=Protein p15-2;
GN   Name=NXT2; ORFNames=BM-025, DC9;
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   NYAP1_HUMAN             Reviewed;         841 AA.
AC   Q6ZVC0; Q6U9Y3; Q8N1V0;
DE   RecName: Full=Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1;
GN   Name=NYAP1; Synonyms=C7orf51;
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
//
ID   NYAP2_HUMAN             Reviewed;         653 AA.
AC   Q9P242; A2RRN4; Q96NL2;
DE   RecName: Full=Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2;
GN   Name=NYAP2; Synonyms=KIAA1486;
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
//
ID   NYX_HUMAN               Reviewed;         481 AA.
AC   Q9GZU5; D3DWC0; Q2M1S4; Q5H983; Q9H4J0;
DE   RecName: Full=Nyctalopin;
DE   Flags: Precursor;
GN   Name=NYX; Synonyms=CLRP;
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   NYNRI_HUMAN             Reviewed;        1898 AA.
AC   Q9P2P1; Q6P153; Q86TR3; Q9HAC4;
DE   RecName: Full=Protein NYNRIN;
DE   AltName: Full=NYN domain and retroviral integrase catalytic domain-containing protein;
DE   AltName: Full=Protein cousin of GIN1;
GN   Name=NYNRIN; Synonyms=CGIN1, KIAA1305;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
//
ID   O10A2_HUMAN             Reviewed;         303 AA.
AC   Q9H208; B2RNL9; Q6IFG9;
DE   RecName: Full=Olfactory receptor 10A2;
DE   AltName: Full=HP4;
DE   AltName: Full=Olfactory receptor OR11-86;
GN   Name=OR10A2; Synonyms=OR10A2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10A4_HUMAN             Reviewed;         315 AA.
AC   Q9H209; B2RNP5; B9EH36; Q96R20;
DE   RecName: Full=Olfactory receptor 10A4;
DE   AltName: Full=HP2;
DE   AltName: Full=Olfactory receptor-like protein JCG5;
GN   Name=OR10A4; Synonyms=OR10A4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
//
ID   O10A5_HUMAN             Reviewed;         317 AA.
AC   Q9H207; O95223; Q52M66; Q96R21; Q96R22;
DE   RecName: Full=Olfactory receptor 10A5;
DE   AltName: Full=HP3;
DE   AltName: Full=Olfactory receptor 10A1;
DE   AltName: Full=Olfactory receptor 11-403;
DE            Short=OR11-403;
DE   AltName: Full=Olfactory receptor-like protein JCG6;
GN   Name=OR10A5; Synonyms=OR10A1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O10A3_HUMAN             Reviewed;         314 AA.
AC   P58181; B9EH39; Q6IF58; Q96R11;
DE   RecName: Full=Olfactory receptor 10A3;
DE   AltName: Full=HTPCRX12;
DE   AltName: Full=Olfactory receptor OR11-97;
GN   Name=OR10A3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O10AC_HUMAN             Reviewed;         325 AA.
AC   Q8NH08;
DE   RecName: Full=Putative olfactory receptor 10AC1;
DE   AltName: Full=Olfactory receptor OR7-5;
GN   Name=OR10AC1P; Synonyms=OR10AC1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10AD_HUMAN             Reviewed;         317 AA.
AC   Q8NGE0; B9EGT9; Q6IFA8;
DE   RecName: Full=Olfactory receptor 10AD1;
DE   AltName: Full=Olfactory receptor OR12-1;
GN   Name=OR10AD1; Synonyms=OR10AD1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10A7_HUMAN             Reviewed;         316 AA.
AC   Q8NGE5; Q6IFD5; Q96R19;
DE   RecName: Full=Olfactory receptor 10A7;
DE   AltName: Full=Olfactory receptor OR12-6;
GN   Name=OR10A7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10A6_HUMAN             Reviewed;         314 AA.
AC   Q8NH74; Q6IF59;
DE   RecName: Full=Olfactory receptor 10A6;
DE   AltName: Full=Olfactory receptor OR11-96;
GN   Name=OR10A6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10AG_HUMAN             Reviewed;         301 AA.
AC   Q8NH19; B2RNH4; Q6IEU3;
DE   RecName: Full=Olfactory receptor 10AG1;
DE   AltName: Full=Olfactory receptor OR11-160;
GN   Name=OR10AG1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10C1_HUMAN             Reviewed;         312 AA.
AC   Q96KK4; Q5SUN7; Q96R18;
DE   RecName: Full=Olfactory receptor 10C1;
DE   AltName: Full=Hs6M1-17;
DE   AltName: Full=Olfactory receptor 10C2;
GN   Name=OR10C1; Synonyms=OR10C2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10D3_HUMAN             Reviewed;         312 AA.
AC   Q8NH80;
DE   RecName: Full=Putative olfactory receptor 10D3;
DE   AltName: Full=HTPCRX09;
DE   AltName: Full=Olfactory receptor OR11-293;
GN   Name=OR10D3; Synonyms=OR10D3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10D4_HUMAN             Reviewed;         298 AA.
AC   Q8NGN7;
DE   RecName: Full=Putative olfactory receptor 10D4;
GN   Name=OR10D4P; Synonyms=OR10D4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G2_HUMAN             Reviewed;         310 AA.
AC   Q8NGC3; B2RPD0;
DE   RecName: Full=Olfactory receptor 10G2;
GN   Name=OR10G2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G4_HUMAN             Reviewed;         311 AA.
AC   Q8NGN3; Q6IEW0;
DE   RecName: Full=Olfactory receptor 10G4;
DE   AltName: Full=Olfactory receptor OR11-278;
GN   Name=OR10G4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G3_HUMAN             Reviewed;         313 AA.
AC   Q8NGC4; Q6IET7; Q96R77;
DE   RecName: Full=Olfactory receptor 10G3;
DE   AltName: Full=Olfactory receptor OR14-40;
GN   Name=OR10G3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G6_HUMAN             Reviewed;         332 AA.
AC   Q8NH81;
DE   RecName: Full=Olfactory receptor 10G6;
DE   AltName: Full=Olfactory receptor OR11-280;
GN   Name=OR10G6; Synonyms=OR10G6P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G7_HUMAN             Reviewed;         311 AA.
AC   Q8NGN6; Q6IFE8;
DE   RecName: Full=Olfactory receptor 10G7;
DE   AltName: Full=Olfactory receptor OR11-283;
GN   Name=OR10G7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G8_HUMAN             Reviewed;         311 AA.
AC   Q8NGN5; B2RNJ3; Q6IEV2;
DE   RecName: Full=Olfactory receptor 10G8;
DE   AltName: Full=Olfactory receptor OR11-282;
GN   Name=OR10G8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10H1_HUMAN             Reviewed;         318 AA.
AC   Q9Y4A9; Q6IFQ2; Q96R59;
DE   RecName: Full=Olfactory receptor 10H1;
DE   AltName: Full=Olfactory receptor OR19-27;
GN   Name=OR10H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10G9_HUMAN             Reviewed;         311 AA.
AC   Q8NGN4;
DE   RecName: Full=Olfactory receptor 10G9;
DE   AltName: Full=Olfactory receptor 10G10;
GN   Name=OR10G9; Synonyms=OR10G10P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10H4_HUMAN             Reviewed;         316 AA.
AC   Q8NGA5; Q6IFJ2; Q96R57;
DE   RecName: Full=Olfactory receptor 10H4;
DE   AltName: Full=Olfactory receptor OR19-28;
GN   Name=OR10H4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10H2_HUMAN             Reviewed;         315 AA.
AC   O60403; Q6IFQ1; Q96R58;
DE   RecName: Full=Olfactory receptor 10H2;
DE   AltName: Full=Olfactory receptor OR19-23;
GN   Name=OR10H2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10H5_HUMAN             Reviewed;         315 AA.
AC   Q8NGA6; Q6IFJ0; Q96R60;
DE   RecName: Full=Olfactory receptor 10H5;
DE   AltName: Full=Olfactory receptor OR19-25;
DE   AltName: Full=Olfactory receptor OR19-26;
GN   Name=OR10H5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10H3_HUMAN             Reviewed;         316 AA.
AC   O60404; Q2HIZ3; Q6IFQ0;
DE   RecName: Full=Olfactory receptor 10H3;
DE   AltName: Full=Olfactory receptor OR19-24;
GN   Name=OR10H3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10J3_HUMAN             Reviewed;         329 AA.
AC   Q5JRS4;
DE   RecName: Full=Olfactory receptor 10J3;
GN   Name=OR10J3; Synonyms=OR10J3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10J4_HUMAN             Reviewed;         311 AA.
AC   P0C629;
DE   RecName: Full=Olfactory receptor 10J4;
GN   Name=OR10J4; Synonyms=OR10J4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10J5_HUMAN             Reviewed;         309 AA.
AC   Q8NHC4; B9EH35; Q6IFH2;
DE   RecName: Full=Olfactory receptor 10J5;
DE   AltName: Full=Olfactory receptor OR1-28;
GN   Name=OR10J5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10J6_HUMAN             Reviewed;         276 AA.
AC   Q8NGY7; Q96R55;
DE   RecName: Full=Putative olfactory receptor 10J6;
GN   Name=OR10J6P; Synonyms=OR10J6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10J1_HUMAN             Reviewed;         320 AA.
AC   P30954; Q2M1M8; Q5VSV1; Q6IET5; Q96R56;
DE   RecName: Full=Olfactory receptor 10J1;
DE   AltName: Full=Olfactory receptor OR1-26;
DE   AltName: Full=Olfactory receptor-like protein HGMP07J;
GN   Name=OR10J1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; TAS:ProtInc.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   O10K1_HUMAN             Reviewed;         313 AA.
AC   Q8NGX5; Q6IFS2;
DE   RecName: Full=Olfactory receptor 10K1;
DE   AltName: Full=Olfactory receptor OR1-6;
GN   Name=OR10K1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10K2_HUMAN             Reviewed;         312 AA.
AC   Q6IF99;
DE   RecName: Full=Olfactory receptor 10K2;
DE   AltName: Full=Olfactory receptor OR1-4;
GN   Name=OR10K2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10P1_HUMAN             Reviewed;         313 AA.
AC   Q8NGE3; B9EGY4;
DE   RecName: Full=Olfactory receptor 10P1;
DE   AltName: Full=Olfactory receptor 10P2;
DE   AltName: Full=Olfactory receptor 10P3;
DE   AltName: Full=Olfactory receptor OR12-7;
GN   Name=OR10P1; Synonyms=OR10P1P, OR10P2P, OR10P3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10Q1_HUMAN             Reviewed;         319 AA.
AC   Q8NGQ4; Q6IFG4;
DE   RecName: Full=Olfactory receptor 10Q1;
DE   AltName: Full=Olfactory receptor OR11-233;
GN   Name=OR10Q1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10R2_HUMAN             Reviewed;         335 AA.
AC   Q8NGX6; Q5VWM8; Q6IFS1; Q96R61;
DE   RecName: Full=Olfactory receptor 10R2;
DE   AltName: Full=Olfactory receptor OR1-8;
GN   Name=OR10R2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10S1_HUMAN             Reviewed;         331 AA.
AC   Q8NGN2; B9EH43; Q6IEV3; Q96R78;
DE   RecName: Full=Olfactory receptor 10S1;
DE   AltName: Full=Olfactory receptor OR11-279;
GN   Name=OR10S1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10T2_HUMAN             Reviewed;         314 AA.
AC   Q8NGX3; Q6IF98;
DE   RecName: Full=Olfactory receptor 10T2;
DE   AltName: Full=Olfactory receptor OR1-3;
GN   Name=OR10T2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10V1_HUMAN             Reviewed;         309 AA.
AC   Q8NGI7; Q6IFD9; Q96R50;
DE   RecName: Full=Olfactory receptor 10V1;
DE   AltName: Full=Olfactory receptor OR11-256;
GN   Name=OR10V1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10W1_HUMAN             Reviewed;         305 AA.
AC   Q8NGF6; A2RUD2; A8MTE1; Q6UXQ2;
DE   RecName: Full=Olfactory receptor 10W1;
DE   AltName: Full=Olfactory receptor OR11-236;
GN   Name=OR10W1; Synonyms=OR10W1P; ORFNames=UNQ6469/PRO34070;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10X1_HUMAN             Reviewed;         326 AA.
AC   Q8NGY0; Q6IFR8;
DE   RecName: Full=Olfactory receptor 10X1;
DE   AltName: Full=Olfactory receptor OR1-14;
GN   Name=OR10X1; Synonyms=OR10X1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O10Z1_HUMAN             Reviewed;         313 AA.
AC   Q8NGY1; Q5VYL0; Q6IFR7;
DE   RecName: Full=Olfactory receptor 10Z1;
DE   AltName: Full=Olfactory receptor OR1-15;
GN   Name=OR10Z1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11A1_HUMAN             Reviewed;         315 AA.
AC   Q9GZK7; A2BF33; A6NFQ3; B0S7T2; Q5ST16; Q9GZK8;
DE   RecName: Full=Olfactory receptor 11A1;
DE   AltName: Full=Hs6M1-18;
DE   AltName: Full=Olfactory receptor 11A2;
DE   AltName: Full=Olfactory receptor OR6-30;
GN   Name=OR11A1; Synonyms=OR11A2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11H1_HUMAN             Reviewed;         326 AA.
AC   Q8NG94; Q6IEX0; Q96R32;
DE   RecName: Full=Olfactory receptor 11H1;
DE   AltName: Full=Olfactory receptor OR22-1;
GN   Name=OR11H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11H2_HUMAN             Reviewed;         326 AA.
AC   Q8NH07;
DE   RecName: Full=Olfactory receptor 11H2;
DE   AltName: Full=Olfactory receptor OR14-1;
GN   Name=OR11H2; Synonyms=C14orf15, OR11H2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11G2_HUMAN             Reviewed;         345 AA.
AC   Q8NGC1; Q6IF09; Q96R33;
DE   RecName: Full=Olfactory receptor 11G2;
DE   AltName: Full=Olfactory receptor OR14-34;
GN   Name=OR11G2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11H4_HUMAN             Reviewed;         324 AA.
AC   Q8NGC9; B2RNQ4; Q6IF07;
DE   RecName: Full=Olfactory receptor 11H4;
DE   AltName: Full=Olfactory receptor OR14-36;
GN   Name=OR11H4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11H6_HUMAN             Reviewed;         330 AA.
AC   Q8NGC7; Q6IF08;
DE   RecName: Full=Olfactory receptor 11H6;
DE   AltName: Full=Olfactory receptor OR14-35;
GN   Name=OR11H6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11HC_HUMAN             Reviewed;         326 AA.
AC   B2RN74;
DE   RecName: Full=Olfactory receptor 11H12;
GN   Name=OR11H12;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11H7_HUMAN             Reviewed;         314 AA.
AC   Q8NGC8;
DE   RecName: Full=Olfactory receptor 11H7;
DE   AltName: Full=Olfactory receptor OR14-32;
GN   Name=OR11H7; Synonyms=OR11H7P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O12D2_HUMAN             Reviewed;         307 AA.
AC   P58182; B0S862; Q5SUN9; Q6IET9;
DE   RecName: Full=Olfactory receptor 12D2;
DE   AltName: Full=Hs6M1-20;
DE   AltName: Full=Olfactory receptor OR6-28;
GN   Name=OR12D2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O12D3_HUMAN             Reviewed;         316 AA.
AC   Q9UGF7; A2BDZ1; Q5SQI8; Q6IF23;
DE   RecName: Full=Olfactory receptor 12D3;
DE   AltName: Full=Hs6M1-27;
DE   AltName: Full=Olfactory receptor OR6-27;
GN   Name=OR12D3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13A1_HUMAN             Reviewed;         328 AA.
AC   Q8NGR1; Q2M3M4; Q5VV57; Q6IFH5; Q6ZMN6;
DE   RecName: Full=Olfactory receptor 13A1;
DE   AltName: Full=Olfactory receptor OR10-3;
GN   Name=OR13A1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O11L1_HUMAN             Reviewed;         322 AA.
AC   Q8NGX0;
DE   RecName: Full=Olfactory receptor 11L1;
GN   Name=OR11L1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13C2_HUMAN             Reviewed;         318 AA.
AC   Q8NGS9; B9EGV8; Q6IF54;
DE   RecName: Full=Olfactory receptor 13C2;
DE   AltName: Full=Olfactory receptor OR9-12;
GN   Name=OR13C2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13C3_HUMAN             Reviewed;         347 AA.
AC   Q8NGS6; Q5VVG1; Q6IF52;
DE   RecName: Full=Olfactory receptor 13C3;
DE   AltName: Full=Olfactory receptor OR9-8;
GN   Name=OR13C3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13C4_HUMAN             Reviewed;         318 AA.
AC   Q8NGS5; Q6IF51; Q96R41;
DE   RecName: Full=Olfactory receptor 13C4;
DE   AltName: Full=Olfactory receptor OR9-7;
GN   Name=OR13C4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13C5_HUMAN             Reviewed;         318 AA.
AC   Q8NGS8; B2RNE5; B9EGW5; Q6IF53;
DE   RecName: Full=Olfactory receptor 13C5;
DE   AltName: Full=Olfactory receptor OR9-11;
GN   Name=OR13C5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13C8_HUMAN             Reviewed;         320 AA.
AC   Q8NGS7; Q5VVG0; Q96R44;
DE   RecName: Full=Olfactory receptor 13C8;
GN   Name=OR13C8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13C9_HUMAN             Reviewed;         318 AA.
AC   Q8NGT0; Q6IFL2;
DE   RecName: Full=Olfactory receptor 13C9;
DE   AltName: Full=Olfactory receptor OR9-13;
GN   Name=OR13C9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13D1_HUMAN             Reviewed;         346 AA.
AC   Q8NGV5; B9EIS1; Q6IFL1;
DE   RecName: Full=Olfactory receptor 13D1;
DE   AltName: Full=Olfactory receptor OR9-15;
GN   Name=OR13D1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13F1_HUMAN             Reviewed;         319 AA.
AC   Q8NGS4; Q6IF50;
DE   RecName: Full=Olfactory receptor 13F1;
DE   AltName: Full=Olfactory receptor OR9-6;
GN   Name=OR13F1;
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13G1_HUMAN             Reviewed;         307 AA.
AC   Q8NGZ3; B2RN80; Q5T2T2; Q6IF86;
DE   RecName: Full=Olfactory receptor 13G1;
DE   AltName: Full=Olfactory receptor OR1-37;
GN   Name=OR13G1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13H1_HUMAN             Reviewed;         308 AA.
AC   Q8NG92; B2RNQ3; Q6IET8; Q96R12;
DE   RecName: Full=Olfactory receptor 13H1;
DE   AltName: Full=Olfactory receptor ORX-1;
GN   Name=OR13H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O13J1_HUMAN             Reviewed;         312 AA.
AC   Q8NGT2; B2RN66; Q6IF20; Q96R40;
DE   RecName: Full=Olfactory receptor 13J1;
DE   AltName: Full=Olfactory receptor OR9-2;
GN   Name=OR13J1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14A2_HUMAN             Reviewed;         314 AA.
AC   Q96R54;
DE   RecName: Full=Olfactory receptor 14A2;
DE   AltName: Full=Olfactory receptor 5AX1;
DE   AltName: Full=Olfactory receptor OR1-31;
GN   Name=OR14A2; Synonyms=OR5AX1, OR5AX1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14AG_HUMAN             Reviewed;         309 AA.
AC   Q8NHC5; Q6IF96;
DE   RecName: Full=Olfactory receptor 14A16;
DE   AltName: Full=Olfactory receptor 5AT1;
DE   AltName: Full=Olfactory receptor OR1-45;
GN   Name=OR14A16; Synonyms=OR5AT1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14CZ_HUMAN             Reviewed;         312 AA.
AC   Q8NHC7; Q6IEZ6;
DE   RecName: Full=Olfactory receptor 14C36;
DE   AltName: Full=Olfactory receptor 5BF1;
DE   AltName: Full=Olfactory receptor OR1-59;
GN   Name=OR14C36; Synonyms=OR5BF1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14I1_HUMAN             Reviewed;         311 AA.
AC   A6ND48;
DE   RecName: Full=Olfactory receptor 14I1;
DE   AltName: Full=Olfactory receptor 5BU1;
GN   Name=OR14I1; Synonyms=OR5BU1, OR5BU1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14J1_HUMAN             Reviewed;         321 AA.
AC   Q9UGF5; A2BEC2; B0V078; Q5ST27;
DE   RecName: Full=Olfactory receptor 14J1;
DE   AltName: Full=Hs6M1-28;
DE   AltName: Full=Olfactory receptor 5U1;
DE   AltName: Full=Olfactory receptor OR6-25;
GN   Name=OR14J1; Synonyms=OR5U1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14K1_HUMAN             Reviewed;         314 AA.
AC   Q8NGZ2; A8MPV5; Q6IF85; Q96R53;
DE   RecName: Full=Olfactory receptor 14K1;
DE   AltName: Full=Olfactory receptor 5AY1;
DE   AltName: Full=Olfactory receptor OR1-39;
GN   Name=OR14K1; Synonyms=OR5AY1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O14L1_HUMAN             Reviewed;         308 AA.
AC   Q8NHC6; Q5JQT0;
DE   RecName: Full=Putative olfactory receptor 14L1;
DE   AltName: Full=Putative olfactory receptor 5AV1;
GN   Name=OR14L1P; Synonyms=OR5AV1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2A12_HUMAN             Reviewed;         310 AA.
AC   Q8NGT7; Q6IF43;
DE   RecName: Full=Olfactory receptor 2A12;
DE   AltName: Full=Olfactory receptor OR7-10;
GN   Name=OR2A12; Synonyms=OR2A12P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2A14_HUMAN             Reviewed;         310 AA.
AC   Q96R47; Q6IF41; Q8NGT8;
DE   RecName: Full=Olfactory receptor 2A14;
DE   AltName: Full=OST182;
DE   AltName: Full=Olfactory receptor 2A6;
DE   AltName: Full=Olfactory receptor OR7-12;
GN   Name=OR2A14; Synonyms=OR2A14P, OR2A6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2A25_HUMAN             Reviewed;         310 AA.
AC   A4D2G3; B2RNC9;
DE   RecName: Full=Olfactory receptor 2A25;
DE   AltName: Full=Olfactory receptor 2A27;
GN   Name=OR2A25; Synonyms=OR2A25P, OR2A27;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2AE1_HUMAN             Reviewed;         323 AA.
AC   Q8NHA4; B2RPD2;
DE   RecName: Full=Olfactory receptor 2AE1;
DE   AltName: Full=Olfactory receptor 2AE2;
GN   Name=OR2AE1; Synonyms=OR2AE2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2AG1_HUMAN             Reviewed;         316 AA.
AC   Q9H205; B9EKV7; Q6IFG7; Q96R26;
DE   RecName: Full=Olfactory receptor 2AG1;
DE   AltName: Full=HT3;
DE   AltName: Full=Olfactory receptor 2AG3;
DE   AltName: Full=Olfactory receptor OR11-79;
GN   Name=OR2AG1; Synonyms=OR2AG3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   O2AG2_HUMAN             Reviewed;         316 AA.
AC   A6NM03;
DE   RecName: Full=Olfactory receptor 2AG2;
GN   Name=OR2AG2; Synonyms=OR2AG2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2AJ1_HUMAN             Reviewed;         328 AA.
AC   Q8NGZ0;
DE   RecName: Full=Olfactory receptor 2AJ1;
GN   Name=OR2AJ1; Synonyms=OR2AJ1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2AK2_HUMAN             Reviewed;         335 AA.
AC   Q8NG84; B2RND1; Q6IF05;
DE   RecName: Full=Olfactory receptor 2AK2;
DE   AltName: Full=Olfactory receptor 2AK1;
DE   AltName: Full=Olfactory receptor OR1-47;
GN   Name=OR2AK2; Synonyms=OR2AK1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2AP1_HUMAN             Reviewed;         309 AA.
AC   Q8NGE2;
DE   RecName: Full=Olfactory receptor 2AP1;
DE   AltName: Full=Olfactory receptor OR12-9;
GN   Name=OR2AP1; Synonyms=OR2AP1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2AT4_HUMAN             Reviewed;         320 AA.
AC   A6NND4; B9EGZ8;
DE   RecName: Full=Olfactory receptor 2AT4;
DE   AltName: Full=Olfactory receptor OR11-265;
GN   Name=OR2AT4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T11_HUMAN             Reviewed;         316 AA.
AC   Q8NH01; Q6IEY6;
DE   RecName: Full=Olfactory receptor 2T11;
DE   AltName: Full=Olfactory receptor OR1-65;
GN   Name=OR2T11;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T12_HUMAN             Reviewed;         320 AA.
AC   Q8NG77;
DE   RecName: Full=Olfactory receptor 2T12;
DE   AltName: Full=Olfactory receptor OR1-57;
GN   Name=OR2T12;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T10_HUMAN             Reviewed;         312 AA.
AC   Q8NGZ9; B2RNK7;
DE   RecName: Full=Olfactory receptor 2T10;
DE   AltName: Full=Olfactory receptor OR1-64;
GN   Name=OR2T10;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T29_HUMAN             Reviewed;         315 AA.
AC   Q8NH02;
DE   RecName: Full=Olfactory receptor 2T29;
GN   Name=OR2T29;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T33_HUMAN             Reviewed;         320 AA.
AC   Q8NG76; B2RNN0;
DE   RecName: Full=Olfactory receptor 2T33;
DE   AltName: Full=Olfactory receptor OR1-56;
GN   Name=OR2T33;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T27_HUMAN             Reviewed;         317 AA.
AC   Q8NH04;
DE   RecName: Full=Olfactory receptor 2T27;
DE   AltName: Full=Olfactory receptor OR1-67;
GN   Name=OR2T27;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T35_HUMAN             Reviewed;         323 AA.
AC   Q8NGX2; Q6IEY7;
DE   RecName: Full=Olfactory receptor 2T35;
DE   AltName: Full=Olfactory receptor OR1-66;
GN   Name=OR2T35;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O2T34_HUMAN             Reviewed;         318 AA.
AC   Q8NGX1; B2RNJ8; Q6IEY5; Q96R31;
DE   RecName: Full=Olfactory receptor 2T34;
DE   AltName: Full=Olfactory receptor OR1-63;
GN   Name=OR2T34;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4A15_HUMAN             Reviewed;         344 AA.
AC   Q8NGL6; Q6IFL4; Q96R65;
DE   RecName: Full=Olfactory receptor 4A15;
DE   AltName: Full=Olfactory receptor OR11-118;
GN   Name=OR4A15;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4A16_HUMAN             Reviewed;         328 AA.
AC   Q8NH70; Q6IFL3;
DE   RecName: Full=Olfactory receptor 4A16;
DE   AltName: Full=Olfactory receptor OR11-117;
GN   Name=OR4A16;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4A47_HUMAN             Reviewed;         309 AA.
AC   Q6IF82;
DE   RecName: Full=Olfactory receptor 4A47;
DE   AltName: Full=Olfactory receptor OR11-113;
GN   Name=OR4A47;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4C45_HUMAN             Reviewed;         311 AA.
AC   A6NMZ5;
DE   RecName: Full=Olfactory receptor 4C45;
GN   Name=OR4C45;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4C46_HUMAN             Reviewed;         309 AA.
AC   A6NHA9;
DE   RecName: Full=Olfactory receptor 4C46;
GN   Name=OR4C46;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4F15_HUMAN             Reviewed;         312 AA.
AC   Q8NGB8; B2RNQ5; Q6IF57; Q96R70;
DE   RecName: Full=Olfactory receptor 4F15;
DE   AltName: Full=Olfactory receptor OR15-14;
GN   Name=OR4F15;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4F17_HUMAN             Reviewed;         305 AA.
AC   Q8NGA8; B2RNE8;
DE   RecName: Full=Olfactory receptor 4F17;
DE   AltName: Full=Olfactory receptor 4F11;
DE   AltName: Full=Olfactory receptor 4F18;
DE   AltName: Full=Olfactory receptor 4F19;
GN   Name=OR4F17; Synonyms=OR4F11P, OR4F18, OR4F19;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51A2_HUMAN             Reviewed;         313 AA.
AC   Q8NGJ7;
DE   RecName: Full=Olfactory receptor 51A2;
GN   Name=OR51A2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51A4_HUMAN             Reviewed;         313 AA.
AC   Q8NGJ6;
DE   RecName: Full=Olfactory receptor 51A4;
GN   Name=OR51A4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O4F21_HUMAN             Reviewed;         312 AA.
AC   O95013; A6NIU1;
DE   RecName: Full=Olfactory receptor 4F21;
GN   Name=OR4F21; Synonyms=OR4F21P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51A7_HUMAN             Reviewed;         312 AA.
AC   Q8NH64; Q6IFH8;
DE   RecName: Full=Olfactory receptor 51A7;
DE   AltName: Full=Olfactory receptor OR11-27;
GN   Name=OR51A7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51B2_HUMAN             Reviewed;         312 AA.
AC   Q9Y5P1; Q96RD4;
DE   RecName: Full=Olfactory receptor 51B2;
DE   AltName: Full=Odorant receptor HOR5'beta3;
DE   AltName: Full=Olfactory receptor 51B1;
GN   Name=OR51B2; Synonyms=OR51B1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51B4_HUMAN             Reviewed;         310 AA.
AC   Q9Y5P0; A7MAV5; Q6NTD7;
DE   RecName: Full=Olfactory receptor 51B4;
DE   AltName: Full=Odorant receptor HOR5'beta1;
GN   Name=OR51B4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51B5_HUMAN             Reviewed;         312 AA.
AC   Q9H339; B2RN59;
DE   RecName: Full=Olfactory receptor 51B5;
DE   AltName: Full=Odorant receptor HOR5'beta5;
DE   AltName: Full=Olfactory receptor OR11-37;
GN   Name=OR51B5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51D1_HUMAN             Reviewed;         324 AA.
AC   Q8NGF3; B9EIK4;
DE   RecName: Full=Olfactory receptor 51D1;
DE   AltName: Full=Olfactory receptor OR11-14;
GN   Name=OR51D1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51B6_HUMAN             Reviewed;         312 AA.
AC   Q9H340;
DE   RecName: Full=Olfactory receptor 51B6;
DE   AltName: Full=Odorant receptor HOR5'beta6;
GN   Name=OR51B6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51E1_HUMAN             Reviewed;         317 AA.
AC   Q8TCB6; A8KAM6; Q5S4P5; Q66X57; Q6IF93;
DE   RecName: Full=Olfactory receptor 51E1;
DE   AltName: Full=D-GPCR;
DE   AltName: Full=G-protein coupled receptor 164;
DE   AltName: Full=Olfactory receptor 52A3;
DE   AltName: Full=Prostate-overexpressed G protein-coupled receptor;
DE   AltName: Full=Prostate-specific G protein-coupled receptor 2;
GN   Name=OR51E1; Synonyms=GPR164, OR51E1P, OR52A3P, POGR, PSGR2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51E2_HUMAN             Reviewed;         320 AA.
AC   Q9H255; B2RA63; Q6IF94;
DE   RecName: Full=Olfactory receptor 51E2;
DE   AltName: Full=HPRAJ;
DE   AltName: Full=Olfactory receptor OR11-16;
DE   AltName: Full=Prostate-specific G-protein coupled receptor;
GN   Name=OR51E2; Synonyms=PSGR;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51F2_HUMAN             Reviewed;         342 AA.
AC   Q8NH61; Q6IFI1;
DE   RecName: Full=Olfactory receptor 51F2;
DE   AltName: Full=Olfactory receptor OR11-23;
GN   Name=OR51F2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51F1_HUMAN             Reviewed;         319 AA.
AC   A6NGY5;
DE   RecName: Full=Olfactory receptor 51F1;
GN   Name=OR51F1; Synonyms=OR51F1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51G2_HUMAN             Reviewed;         314 AA.
AC   Q8NGK0; Q6IFH7;
DE   RecName: Full=Olfactory receptor 51G2;
DE   AltName: Full=Olfactory receptor OR11-28;
GN   Name=OR51G2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51G1_HUMAN             Reviewed;         321 AA.
AC   Q8NGK1; B9EGW8; Q6IFH6;
DE   RecName: Full=Olfactory receptor 51G1;
DE   AltName: Full=Olfactory receptor 51G3;
DE   AltName: Full=Olfactory receptor OR11-29;
GN   Name=OR51G1; Synonyms=OR51G3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51H1_HUMAN             Reviewed;         302 AA.
AC   Q8NH63; Q6IFI3;
DE   RecName: Full=Putative olfactory receptor 51H1;
DE   AltName: Full=Olfactory receptor OR11-25;
GN   Name=OR51H1P; Synonyms=OR51H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51I2_HUMAN             Reviewed;         312 AA.
AC   Q9H344; Q6IF81;
DE   RecName: Full=Olfactory receptor 51I2;
DE   AltName: Full=Odorant receptor HOR5'beta12;
DE   AltName: Full=Olfactory receptor OR11-38;
GN   Name=OR51I2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51I1_HUMAN             Reviewed;         314 AA.
AC   Q9H343; B9EKW2; Q6IF33;
DE   RecName: Full=Olfactory receptor 51I1;
DE   AltName: Full=Odorant receptor HOR5'beta11;
DE   AltName: Full=Olfactory receptor OR11-39;
GN   Name=OR51I1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51J1_HUMAN             Reviewed;         316 AA.
AC   Q9H342;
DE   RecName: Full=Olfactory receptor 51J1;
DE   AltName: Full=Odorant receptor HOR5'beta8;
DE   AltName: Full=Olfactory receptor 51J2;
GN   Name=OR51J1; Synonyms=OR51J1P, OR51J2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51L1_HUMAN             Reviewed;         315 AA.
AC   Q8NGJ5; Q6IFE5;
DE   RecName: Full=Olfactory receptor 51L1;
DE   AltName: Full=Olfactory receptor OR11-31;
GN   Name=OR51L1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51M1_HUMAN             Reviewed;         326 AA.
AC   Q9H341; Q6IF80;
DE   RecName: Full=Olfactory receptor 51M1;
DE   AltName: Full=Odorant receptor HOR5'beta7;
DE   AltName: Full=Olfactory receptor OR11-40;
GN   Name=OR51M1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O51Q1_HUMAN             Reviewed;         317 AA.
AC   Q8NH59; B2RNN1;
DE   RecName: Full=Olfactory receptor 51Q1;
GN   Name=OR51Q1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51S1_HUMAN             Reviewed;         323 AA.
AC   Q8NGJ8; B9EGZ1; Q6IFI2;
DE   RecName: Full=Olfactory receptor 51S1;
DE   AltName: Full=Olfactory receptor OR11-24;
GN   Name=OR51S1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51T1_HUMAN             Reviewed;         327 AA.
AC   Q8NGJ9; Q6IFH9;
DE   RecName: Full=Olfactory receptor 51T1;
DE   AltName: Full=Olfactory receptor OR11-26;
GN   Name=OR51T1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52A1_HUMAN             Reviewed;         312 AA.
AC   Q9UKL2; Q6IF31;
DE   RecName: Full=Olfactory receptor 52A1;
DE   AltName: Full=HPFH1OR;
DE   AltName: Full=Odorant receptor HOR3'beta4;
DE   AltName: Full=Olfactory receptor OR11-319;
GN   Name=OR52A1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007608; P:sensory perception of smell; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   O52A4_HUMAN             Reviewed;         304 AA.
AC   A6NMU1;
DE   RecName: Full=Putative olfactory receptor 52A4;
GN   Name=OR52A4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O51V1_HUMAN             Reviewed;         321 AA.
AC   Q9H2C8;
DE   RecName: Full=Olfactory receptor 51V1;
DE   AltName: Full=Odorant receptor HOR3'beta1;
DE   AltName: Full=Olfactory receptor 51A12;
DE   AltName: Full=Olfactory receptor OR11-36;
GN   Name=OR51V1; Synonyms=OR51A12;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O52A5_HUMAN             Reviewed;         316 AA.
AC   Q9H2C5;
DE   RecName: Full=Olfactory receptor 52A5;
DE   AltName: Full=Odorant receptor HOR3'beta5;
DE   AltName: Full=Olfactory receptor OR11-33;
GN   Name=OR52A5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O52B2_HUMAN             Reviewed;         323 AA.
AC   Q96RD2; Q8NGM7;
DE   RecName: Full=Olfactory receptor 52B2;
DE   AltName: Full=Olfactory receptor OR11-70;
GN   Name=OR52B2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52E1_HUMAN             Reviewed;         308 AA.
AC   Q8NGJ3;
DE   RecName: Full=Olfactory receptor 52E1;
GN   Name=OR52E1; Synonyms=OR52E1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52D1_HUMAN             Reviewed;         318 AA.
AC   Q9H346; B9EGY9; Q6IFI6;
DE   RecName: Full=Olfactory receptor 52D1;
DE   AltName: Full=Odorant receptor HOR5'beta14;
DE   AltName: Full=Olfactory receptor OR11-43;
GN   Name=OR52D1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O52E2_HUMAN             Reviewed;         325 AA.
AC   Q8NGJ4;
DE   RecName: Full=Olfactory receptor 52E2;
GN   Name=OR52E2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52B6_HUMAN             Reviewed;         335 AA.
AC   Q8NGF0; Q6IFI7;
DE   RecName: Full=Olfactory receptor 52B6;
DE   AltName: Full=Olfactory receptor OR11-47;
GN   Name=OR52B6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52E6_HUMAN             Reviewed;         313 AA.
AC   Q96RD3; Q6IFF8;
DE   RecName: Full=Olfactory receptor 52E6;
DE   AltName: Full=Olfactory receptor OR11-58;
GN   Name=OR52E6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52E5_HUMAN             Reviewed;         327 AA.
AC   Q8NH55;
DE   RecName: Full=Olfactory receptor 52E5;
GN   Name=OR52E5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52E4_HUMAN             Reviewed;         312 AA.
AC   Q8NGH9; Q6IFG0;
DE   RecName: Full=Olfactory receptor 52E4;
DE   AltName: Full=Olfactory receptor OR11-55;
GN   Name=OR52E4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52B4_HUMAN             Reviewed;         314 AA.
AC   Q8NGK2; A6NP68; Q6IFK6;
DE   RecName: Full=Olfactory receptor 52B4;
DE   AltName: Full=Olfactory receptor OR11-3;
GN   Name=OR52B4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52E8_HUMAN             Reviewed;         317 AA.
AC   Q6IFG1; B9EH38;
DE   RecName: Full=Olfactory receptor 52E8;
DE   AltName: Full=Olfactory receptor OR11-54;
GN   Name=OR52E8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52I1_HUMAN             Reviewed;         324 AA.
AC   Q8NGK6; Q6IF91;
DE   RecName: Full=Olfactory receptor 52I1;
DE   AltName: Full=Olfactory receptor OR11-13;
GN   Name=OR52I1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52H1_HUMAN             Reviewed;         320 AA.
AC   Q8NGJ2; B9EH26; Q6IF79;
DE   RecName: Full=Olfactory receptor 52H1;
DE   AltName: Full=Olfactory receptor OR11-45;
GN   Name=OR52H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52I2_HUMAN             Reviewed;         350 AA.
AC   Q8NH67; B2RNJ5; B9EKV8; Q6IFJ8;
DE   RecName: Full=Olfactory receptor 52I2;
DE   AltName: Full=Olfactory receptor OR11-12;
GN   Name=OR52I2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52J3_HUMAN             Reviewed;         311 AA.
AC   Q8NH60; Q6IFE4;
DE   RecName: Full=Olfactory receptor 52J3;
DE   AltName: Full=Olfactory receptor OR11-32;
GN   Name=OR52J3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52K1_HUMAN             Reviewed;         314 AA.
AC   Q8NGK4; B9EH54; Q6IFK5;
DE   RecName: Full=Olfactory receptor 52K1;
DE   AltName: Full=Olfactory receptor OR11-8;
GN   Name=OR52K1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52K2_HUMAN             Reviewed;         314 AA.
AC   Q8NGK3; A8MUY8; B2RP35; Q6IFK4;
DE   RecName: Full=Olfactory receptor 52K2;
DE   AltName: Full=Olfactory receptor OR11-7;
GN   Name=OR52K2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52L1_HUMAN             Reviewed;         329 AA.
AC   Q8NGH7; B2RPA6; Q6IFK9;
DE   RecName: Full=Olfactory receptor 52L1;
DE   AltName: Full=Olfactory receptor OR11-50;
GN   Name=OR52L1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52M1_HUMAN             Reviewed;         317 AA.
AC   Q8NGK5;
DE   RecName: Full=Olfactory receptor 52M1;
DE   AltName: Full=Olfactory receptor OR11-11;
GN   Name=OR52M1; Synonyms=OR52M1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52L2_HUMAN             Reviewed;         319 AA.
AC   Q8NGH6; Q6IFK8;
DE   RecName: Full=Putative olfactory receptor 52L2;
DE   AltName: Full=Olfactory receptor OR11-74;
GN   Name=OR52L2P; Synonyms=OR52L2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52N1_HUMAN             Reviewed;         320 AA.
AC   Q8NH53; Q6IFF6;
DE   RecName: Full=Olfactory receptor 52N1;
DE   AltName: Full=Olfactory receptor OR11-61;
GN   Name=OR52N1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52N2_HUMAN             Reviewed;         321 AA.
AC   Q8NGI0; Q6IFF9;
DE   RecName: Full=Olfactory receptor 52N2;
DE   AltName: Full=Olfactory receptor OR11-57;
GN   Name=OR52N2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52N4_HUMAN             Reviewed;         321 AA.
AC   Q8NGI2; B2RNP8; Q6IF77;
DE   RecName: Full=Olfactory receptor 52N4;
DE   AltName: Full=Olfactory receptor OR11-64;
GN   Name=OR52N4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52N5_HUMAN             Reviewed;         324 AA.
AC   Q8NH56; B9EH12; Q6IFG2;
DE   RecName: Full=Olfactory receptor 52N5;
DE   AltName: Full=Olfactory receptor OR11-62;
GN   Name=OR52N5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52P1_HUMAN             Reviewed;         321 AA.
AC   Q8NH57;
DE   RecName: Full=Putative olfactory receptor 52P1;
GN   Name=OR52P1P; Synonyms=OR52P1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52Z1_HUMAN             Reviewed;         297 AA.
AC   P0C646;
DE   RecName: Full=Olfactory receptor 52Z1;
GN   Name=OR52Z1; Synonyms=OR52Z1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52R1_HUMAN             Reviewed;         315 AA.
AC   Q8NGF1; Q6IFI0;
DE   RecName: Full=Olfactory receptor 52R1;
DE   AltName: Full=Olfactory receptor OR11-22;
GN   Name=OR52R1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O52W1_HUMAN             Reviewed;         320 AA.
AC   Q6IF63; Q8NH78;
DE   RecName: Full=Olfactory receptor 52W1;
DE   AltName: Full=Olfactory receptor OR11-71;
GN   Name=OR52W1; Synonyms=OR52W1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56A1_HUMAN             Reviewed;         318 AA.
AC   Q8NGH5; B2RNI2; Q6IFL0;
DE   RecName: Full=Olfactory receptor 56A1;
DE   AltName: Full=Olfactory receptor OR11-75;
GN   Name=OR56A1;
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56A3_HUMAN             Reviewed;         315 AA.
AC   Q8NH54; A6NN77; Q6IFF7;
DE   RecName: Full=Olfactory receptor 56A3;
DE   AltName: Full=Olfactory receptor 56A6;
GN   Name=OR56A3; Synonyms=OR56A3P, OR56A6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56A4_HUMAN             Reviewed;         313 AA.
AC   Q8NGH8; B9EH17;
DE   RecName: Full=Olfactory receptor 56A4;
DE   AltName: Full=Olfactory receptor OR11-49;
GN   Name=OR56A4;
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56A5_HUMAN             Reviewed;         313 AA.
AC   P0C7T3;
DE   RecName: Full=Olfactory receptor 56A5;
GN   Name=OR56A5; Synonyms=OR56A5P;
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56B1_HUMAN             Reviewed;         324 AA.
AC   Q8NGI3; B2RNY6; B3KV42; Q6IF76;
DE   RecName: Full=Olfactory receptor 56B1;
DE   AltName: Full=Olfactory receptor OR11-65;
GN   Name=OR56B1; Synonyms=OR56B1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56B4_HUMAN             Reviewed;         319 AA.
AC   Q8NH76; Q6IFD7;
DE   RecName: Full=Olfactory receptor 56B4;
DE   AltName: Full=Olfactory receptor OR11-67;
GN   Name=OR56B4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AC1_HUMAN             Reviewed;         307 AA.
AC   P0C628;
DE   RecName: Full=Olfactory receptor 5AC1;
DE   AltName: Full=Olfactory receptor OR3-2;
GN   Name=OR5AC1; Synonyms=OR5AC1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AK2_HUMAN             Reviewed;         309 AA.
AC   Q8NH90; B2RNZ9;
DE   RecName: Full=Olfactory receptor 5AK2;
GN   Name=OR5AK2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O56B2_HUMAN             Reviewed;         322 AA.
AC   Q8NGI1;
DE   RecName: Full=Putative olfactory receptor 56B2;
GN   Name=OR56B2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AK3_HUMAN             Reviewed;         298 AA.
AC   Q8NH89;
DE   RecName: Full=Putative olfactory receptor 5AK3;
GN   Name=OR5AK3P; Synonyms=OR5AK3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AL1_HUMAN             Reviewed;         328 AA.
AC   P0C617;
DE   RecName: Full=Olfactory receptor 5AL1;
DE   AltName: Full=Olfactory receptor OR11-184;
GN   Name=OR5AL1; Synonyms=OR5AL1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AC2_HUMAN             Reviewed;         309 AA.
AC   Q9NZP5;
DE   RecName: Full=Olfactory receptor 5AC2;
DE   AltName: Full=HSA1;
GN   Name=OR5AC2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   O5AR1_HUMAN             Reviewed;         310 AA.
AC   Q8NGP9; Q6IF61;
DE   RecName: Full=Olfactory receptor 5AR1;
DE   AltName: Full=Olfactory receptor OR11-209;
GN   Name=OR5AR1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AP2_HUMAN             Reviewed;         316 AA.
AC   Q8NGF4; B2RNM8;
DE   RecName: Full=Olfactory receptor 5AP2;
GN   Name=OR5AP2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AN1_HUMAN             Reviewed;         311 AA.
AC   Q8NGI8; B9EIS2; Q6IEV4;
DE   RecName: Full=Olfactory receptor 5AN1;
DE   AltName: Full=Olfactory receptor OR11-244;
GN   Name=OR5AN1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AS1_HUMAN             Reviewed;         324 AA.
AC   Q8N127; Q6IFB8;
DE   RecName: Full=Olfactory receptor 5AS1;
DE   AltName: Full=Olfactory receptor OR11-168;
GN   Name=OR5AS1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5AU1_HUMAN             Reviewed;         362 AA.
AC   Q8NGC0; B2RP78; Q6IEU2; Q96R10;
DE   RecName: Full=Olfactory receptor 5AU1;
DE   AltName: Full=Olfactory receptor OR14-38;
GN   Name=OR5AU1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5H15_HUMAN             Reviewed;         313 AA.
AC   A6NDH6;
DE   RecName: Full=Olfactory receptor 5H15;
GN   Name=OR5H15;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O5H14_HUMAN             Reviewed;         310 AA.
AC   A6NHG9; B9EH15;
DE   RecName: Full=Olfactory receptor 5H14;
GN   Name=OR5H14;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O6C68_HUMAN             Reviewed;         312 AA.
AC   A6NDL8;
DE   RecName: Full=Olfactory receptor 6C68;
GN   Name=OR6C68;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O6C70_HUMAN             Reviewed;         312 AA.
AC   A6NIJ9;
DE   RecName: Full=Olfactory receptor 6C70;
GN   Name=OR6C70;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O6C65_HUMAN             Reviewed;         312 AA.
AC   A6NJZ3; B2RNH9;
DE   RecName: Full=Olfactory receptor 6C65;
GN   Name=OR6C65;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O6C74_HUMAN             Reviewed;         312 AA.
AC   A6NCV1;
DE   RecName: Full=Olfactory receptor 6C74;
GN   Name=OR6C74;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O6C75_HUMAN             Reviewed;         312 AA.
AC   A6NL08;
DE   RecName: Full=Olfactory receptor 6C75;
GN   Name=OR6C75;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O7E24_HUMAN             Reviewed;         339 AA.
AC   Q6IFN5; B9EJD9; Q9UPJ1;
DE   RecName: Full=Olfactory receptor 7E24;
DE   AltName: Full=Olfactory receptor OR19-14;
GN   Name=OR7E24; Synonyms=OR7E24P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   O6C76_HUMAN             Reviewed;         312 AA.
AC   A6NM76;
DE   RecName: Full=Olfactory receptor 6C76;
GN   Name=OR6C76;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OAF_HUMAN               Reviewed;         273 AA.
AC   Q86UD1;
DE   RecName: Full=Out at first protein homolog;
DE   AltName: Full=HCV NS5A-transactivated protein 13 target protein 2;
DE   Flags: Precursor;
GN   Name=OAF; Synonyms=NS5ATP13TP2;
//
ID   OARD1_HUMAN             Reviewed;         152 AA.
AC   Q9Y530; A6NEK4; A8K4H4; Q96F23;
DE   RecName: Full=O-acetyl-ADP-ribose deacetylase 1;
DE            EC=3.5.1.-;
GN   Name=OARD1; Synonyms=C6orf130;
DR   GO; GO:0019213; F:deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001883; F:purine nucleoside binding; IDA:UniProtKB.
DR   GO; GO:0042278; P:purine nucleoside metabolic process; IDA:UniProtKB.
//
ID   OAS1_HUMAN              Reviewed;         400 AA.
AC   P00973; A8K4N8; P04820; P29080; P29081; P78485; P78486; Q16700;
AC   Q16701; Q1PG42; Q3ZM01; Q53GC5; Q53YA4; Q6A1Z3; Q6IPC6; Q6P7N9;
AC   Q96J61;
DE   RecName: Full=2'-5'-oligoadenylate synthase 1;
DE            Short=(2-5')oligo(A) synthase 1;
DE            Short=2-5A synthase 1;
DE            EC=2.7.7.84;
DE   AltName: Full=E18/E16;
DE   AltName: Full=p46/p42 OAS;
GN   Name=OAS1; Synonyms=OIAS;
DR   GO; GO:0001730; F:2'-5'-oligoadenylate synthetase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProt.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:UniProt.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0060700; P:regulation of ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   OAS2_HUMAN              Reviewed;         719 AA.
AC   P29728; A8K9T1; Q6PJ33; Q86XX8;
DE   RecName: Full=2'-5'-oligoadenylate synthase 2;
DE            Short=(2-5')oligo(A) synthase 2;
DE            Short=2-5A synthase 2;
DE            EC=2.7.7.84;
DE   AltName: Full=p69 OAS / p71 OAS;
DE            Short=p69OAS / p71OAS;
GN   Name=OAS2;
DR   GO; GO:0001730; F:2'-5'-oligoadenylate synthetase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IMP:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; IDA:UniProtKB.
DR   GO; GO:0018377; P:protein myristoylation; IMP:UniProtKB.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   OAS3_HUMAN              Reviewed;        1087 AA.
AC   Q9Y6K5; Q2HJ14; Q9H3P5;
DE   RecName: Full=2'-5'-oligoadenylate synthase 3;
DE            Short=(2-5')oligo(A) synthase 3;
DE            Short=2-5A synthase 3;
DE            EC=2.7.7.84;
DE   AltName: Full=p100 OAS;
DE            Short=p100OAS;
GN   Name=OAS3; ORFNames=P/OKcl.4;
DR   GO; GO:0001730; F:2'-5'-oligoadenylate synthetase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0060700; P:regulation of ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   OASL_HUMAN              Reviewed;         514 AA.
AC   Q15646; B2RAZ2; I1YDD2; O75686; Q17R95; Q9Y6K6; Q9Y6K7;
DE   RecName: Full=2'-5'-oligoadenylate synthase-like protein;
DE   AltName: Full=2'-5'-OAS-related protein;
DE            Short=2'-5'-OAS-RP;
DE   AltName: Full=59 kDa 2'-5'-oligoadenylate synthase-like protein;
DE   AltName: Full=Thyroid receptor-interacting protein 14;
DE            Short=TR-interacting protein 14;
DE            Short=TRIP-14;
DE   AltName: Full=p59 OASL;
DE            Short=p59OASL;
GN   Name=OASL; Synonyms=TRIP14;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; TAS:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   OAT_HUMAN               Reviewed;         439 AA.
AC   P04181; D3DRF0; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03;
DE   RecName: Full=Ornithine aminotransferase, mitochondrial;
DE            EC=2.6.1.13;
DE   AltName: Full=Ornithine delta-aminotransferase;
DE   AltName: Full=Ornithine--oxo-acid aminotransferase;
DE   Contains:
DE     RecName: Full=Ornithine aminotransferase, hepatic form;
DE   Contains:
DE     RecName: Full=Ornithine aminotransferase, renal form;
DE   Flags: Precursor;
GN   Name=OAT;
DR   GO; GO:0004587; F:ornithine-oxo-acid transaminase activity; EXP:Reactome.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0034214; P:protein hexamerization; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   OAZ1_HUMAN              Reviewed;         228 AA.
AC   P54368; O43382; Q14989; Q92595; Q9UPL9;
DE   RecName: Full=Ornithine decarboxylase antizyme 1;
DE            Short=ODC-Az;
GN   Name=OAZ1; Synonyms=OAZ;
DR   GO; GO:0008073; F:ornithine decarboxylase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006596; P:polyamine biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   OAZ2_HUMAN              Reviewed;         189 AA.
AC   O95190;
DE   RecName: Full=Ornithine decarboxylase antizyme 2;
DE            Short=AZ2;
DE            Short=ODC-Az 2;
GN   Name=OAZ2;
DR   GO; GO:0008073; F:ornithine decarboxylase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:ProtInc.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   OAZ3_HUMAN              Reviewed;         187 AA.
AC   Q9UMX2;
DE   RecName: Full=Ornithine decarboxylase antizyme 3;
DE            Short=AZ3;
DE            Short=ODC-Az 3;
GN   Name=OAZ3;
DR   GO; GO:0008073; F:ornithine decarboxylase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   OBF1_HUMAN              Reviewed;         256 AA.
AC   Q16633; B2R8Z9; Q14983;
DE   RecName: Full=POU domain class 2-associating factor 1;
DE   AltName: Full=B-cell-specific coactivator OBF-1;
DE   AltName: Full=BOB-1;
DE   AltName: Full=OCA-B;
DE   AltName: Full=OCT-binding factor 1;
GN   Name=POU2AF1; Synonyms=OBF1;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   OBP2B_HUMAN             Reviewed;         170 AA.
AC   Q9NPH6; Q5VSP6; Q9NY51; Q9NY52;
DE   RecName: Full=Odorant-binding protein 2b;
DE   AltName: Full=Odorant-binding protein IIb;
DE            Short=OBPIIb;
DE   Flags: Precursor;
GN   Name=OBP2B; ORFNames=UNQ653/PRO1283;
DR   GO; GO:0005549; F:odorant binding; NAS:UniProtKB.
DR   GO; GO:0007635; P:chemosensory behavior; TAS:ProtInc.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   OBP2A_HUMAN             Reviewed;         170 AA.
AC   Q9NY56; Q5T8A3; Q9NY50; Q9NY53; Q9NY54; Q9NY55;
DE   RecName: Full=Odorant-binding protein 2a;
DE   AltName: Full=Odorant-binding protein IIa;
DE            Short=OBPIIa;
DE   Flags: Precursor;
GN   Name=OBP2A;
DR   GO; GO:0005549; F:odorant binding; NAS:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; TAS:ProtInc.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   OBRG_HUMAN              Reviewed;         131 AA.
AC   O15243; Q6FHL5;
DE   RecName: Full=Leptin receptor gene-related protein;
DE   AltName: Full=Endospanin-1;
DE   AltName: Full=Leptin receptor overlapping transcript protein;
DE   AltName: Full=OB-R gene-related protein;
DE            Short=OB-RGRP;
GN   Name=LEPROT; Synonyms=LEPR, OBR;
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0060400; P:negative regulation of growth hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:UniProtKB.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IDA:UniProtKB.
//
ID   OBSCN_HUMAN             Reviewed;        7968 AA.
AC   Q5VST9; Q2A664; Q5T7G8; Q5T7G9; Q5VSU2; Q86YC7; Q8NHN0; Q8NHN1;
AC   Q8NHN2; Q8NHN3; Q8NHN4; Q8NHN5; Q8NHN6; Q8NHN7; Q8NHN8; Q8NHN9;
AC   Q96AA2; Q9HCD3; Q9HCL6;
DE   RecName: Full=Obscurin;
DE            EC=2.7.11.1;
DE   AltName: Full=Obscurin-RhoGEF;
DE   AltName: Full=Obscurin-myosin light chain kinase;
DE            Short=Obscurin-MLCK;
GN   Name=OBSCN; Synonyms=KIAA1556, KIAA1639;
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0008307; F:structural constituent of muscle; NAS:BHF-UCL.
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0036309; P:protein localization to M-band; ISS:BHF-UCL.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0045214; P:sarcomere organization; TAS:BHF-UCL.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   OBSL1_HUMAN             Reviewed;        1896 AA.
AC   O75147; A4KVA4; A4KVA5; Q96IW3; S4R3M6;
DE   RecName: Full=Obscurin-like protein 1;
GN   Name=OBSL1; Synonyms=KIAA0657;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; NAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0055003; P:cardiac myofibril assembly; NAS:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:BHF-UCL.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IMP:UniProtKB.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IMP:UniProtKB.
//
ID   OC90_HUMAN              Reviewed;         493 AA.
AC   Q02509; B4DNG8;
DE   RecName: Full=Otoconin-90;
DE            Short=Oc90;
DE   AltName: Full=Phospholipase A2 homolog;
DE   Flags: Precursor;
GN   Name=OC90; Synonyms=PLA2L;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
//
ID   OCAD1_HUMAN             Reviewed;         245 AA.
AC   Q9NX40; C9K030; G8JLN7; Q9BZE8;
DE   RecName: Full=OCIA domain-containing protein 1;
DE   AltName: Full=Ovarian carcinoma immunoreactive antigen;
GN   Name=OCIAD1; Synonyms=OCIA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   OCAD2_HUMAN             Reviewed;         154 AA.
AC   Q56VL3; B4DPE7; Q8N544;
DE   RecName: Full=OCIA domain-containing protein 2;
DE   AltName: Full=Ovarian carcinoma immunoreactive antigen-like protein;
GN   Name=OCIAD2;
//
ID   OCC1_HUMAN              Reviewed;          63 AA.
AC   Q8TAD7;
DE   RecName: Full=Overexpressed in colon carcinoma 1 protein;
DE            Short=OCC-1;
DE   AltName: Full=AGD3;
GN   Name=OCC1; Synonyms=C12orf75;
//
ID   OCEL1_HUMAN             Reviewed;         264 AA.
AC   Q9H607;
DE   RecName: Full=Occludin/ELL domain-containing protein 1;
GN   Name=OCEL1;
//
ID   OCLN_HUMAN              Reviewed;         522 AA.
AC   Q16625; B5BU70; D2DU64; D2DU65; D2IGC0; D2IGC1; E2CYV9; Q5U1V4;
AC   Q8N6K1;
DE   RecName: Full=Occludin;
GN   Name=OCLN;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProt.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008119; F:thiopurine S-methyltransferase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; IMP:MGI.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0046498; P:S-adenosylhomocysteine metabolic process; IEA:Ensembl.
DR   GO; GO:0046500; P:S-adenosylmethionine metabolic process; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IMP:UniProt.
//
ID   OCM2_HUMAN              Reviewed;         109 AA.
AC   P0CE71; P32930; Q6ISI5; Q75MW0;
DE   RecName: Full=Putative oncomodulin-2;
GN   Name=OCM2; Synonyms=OCMN;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
//
ID   OCR1_HUMAN              Reviewed;          76 AA.
AC   Q9BZK8;
DE   RecName: Full=Ovarian cancer-related protein 1;
GN   Name=OCR1;
//
ID   OCRL_HUMAN              Reviewed;         901 AA.
AC   Q01968; A6NKI1; A8KAP2; B7ZLX2; O60800; Q15684; Q15774; Q4VY09;
AC   Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5;
DE   RecName: Full=Inositol polyphosphate 5-phosphatase OCRL-1;
DE            EC=3.1.3.36;
DE   AltName: Full=Lowe oculocerebrorenal syndrome protein;
GN   Name=OCRL; Synonyms=INPP5F, OCRL1;
DR   GO; GO:0052745; F:inositol phosphate phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IDA:FlyBase.
DR   GO; GO:0048365; F:Rac GTPase binding; IPI:FlyBase.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:FlyBase.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   OCSTP_HUMAN             Reviewed;         566 AA.
AC   Q9BR26;
DE   RecName: Full=Osteoclast stimulatory transmembrane protein;
DE            Short=OC-STAMP;
GN   Name=OCSTAMP; Synonyms=C20orf123;
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; ISS:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:UniProtKB.
DR   GO; GO:0072674; P:multinuclear osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0034241; P:positive regulation of macrophage fusion; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0090290; P:positive regulation of osteoclast proliferation; ISS:UniProtKB.
//
ID   OCTC_HUMAN              Reviewed;         612 AA.
AC   Q9UKG9; A4D1D6; E7EQF2; Q86V17; Q8IUW9; Q9Y6I2;
DE   RecName: Full=Peroxisomal carnitine O-octanoyltransferase;
DE            Short=COT;
DE            EC=2.3.1.137;
GN   Name=CROT; Synonyms=COT;
DR   GO; GO:0008458; F:carnitine O-octanoyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0009437; P:carnitine metabolic process; ISS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0015936; P:coenzyme A metabolic process; ISS:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; IMP:UniProtKB.
DR   GO; GO:0015908; P:fatty acid transport; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IDA:UniProtKB.
DR   GO; GO:0051791; P:medium-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   OD3L2_HUMAN             Reviewed;         289 AA.
AC   Q3SX64; Q3SX65; Q8N1L2;
DE   RecName: Full=Outer dense fiber protein 3-like protein 2;
GN   Name=ODF3L2; Synonyms=C19orf19;
//
ID   OD3L1_HUMAN             Reviewed;         274 AA.
AC   Q8IXM7;
DE   RecName: Full=Outer dense fiber protein 3-like protein 1;
GN   Name=ODF3L1;
//
ID   ODAM_HUMAN              Reviewed;         279 AA.
AC   A1E959; Q8WWE5; Q9NWZ9;
DE   RecName: Full=Odontogenic ameloblast-associated protein;
DE   AltName: Full=Apin;
DE   Flags: Precursor;
GN   Name=ODAM; Synonyms=APIN;
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEP:HGNC.
//
ID   ODB2_HUMAN              Reviewed;         482 AA.
AC   P11182; B2R811; Q5VVL8;
DE   RecName: Full=Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial;
DE            EC=2.3.1.168;
DE   AltName: Full=Branched-chain alpha-keto acid dehydrogenase complex component E2;
DE            Short=BCKAD-E2;
DE            Short=BCKADE2;
DE   AltName: Full=Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex;
DE   AltName: Full=Dihydrolipoamide branched chain transacylase;
DE   AltName: Full=Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase;
DE   Flags: Precursor;
GN   Name=DBT; Synonyms=BCATE2;
DR   GO; GO:0043754; F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ODBA_HUMAN              Reviewed;         445 AA.
AC   P12694; Q16034; Q16472;
DE   RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial;
DE            EC=1.2.4.4;
DE   AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain;
DE            Short=BCKDE1A;
DE            Short=BCKDH E1-alpha;
DE   Flags: Precursor;
GN   Name=BCKDHA;
DR   GO; GO:0003863; F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; TAS:ProtInc.
DR   GO; GO:0003826; F:alpha-ketoacid dehydrogenase activity; IDA:HGNC.
DR   GO; GO:0016831; F:carboxy-lyase activity; TAS:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; IDA:HGNC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ODBB_HUMAN              Reviewed;         392 AA.
AC   P21953; Q9BQL0;
DE   RecName: Full=2-oxoisovalerate dehydrogenase subunit beta, mitochondrial;
DE            EC=1.2.4.4;
DE   AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component beta chain;
DE            Short=BCKDE1B;
DE            Short=BCKDH E1-beta;
DE   Flags: Precursor;
GN   Name=BCKDHB;
DR   GO; GO:0003863; F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; TAS:ProtInc.
DR   GO; GO:0003826; F:alpha-ketoacid dehydrogenase activity; IEA:Ensembl.
DR   GO; GO:0016831; F:carboxy-lyase activity; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; IMP:HGNC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ODC_HUMAN               Reviewed;         299 AA.
AC   Q9BQT8; A8K0L0; G3V4L5; Q3MJ99;
DE   RecName: Full=Mitochondrial 2-oxodicarboxylate carrier;
DE   AltName: Full=Solute carrier family 25 member 21;
GN   Name=SLC25A21; Synonyms=ODC;
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   ODF2L_HUMAN             Reviewed;         636 AA.
AC   Q9ULJ1; A8MU56; B4E037; Q05C40; Q5BJG5; Q5TBX3; Q5TBX4; Q86X31;
DE   RecName: Full=Outer dense fiber protein 2-like;
GN   Name=ODF2L; Synonyms=KIAA1229;
//
ID   ODF3A_HUMAN             Reviewed;         254 AA.
AC   Q96PU9; B7ZLT0; Q69YX0;
DE   RecName: Full=Outer dense fiber protein 3;
DE   AltName: Full=Outer dense fiber of sperm tails protein 3;
DE   AltName: Full=Sperm tail protein SHIPPO 1;
DE   AltName: Full=Transcript induced in spermiogenesis protein 50;
GN   Name=ODF3; Synonyms=SHIPPO1, TISP50;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   ODF3B_HUMAN             Reviewed;         253 AA.
AC   A8MYP8; A0PK18;
DE   RecName: Full=Outer dense fiber protein 3B;
DE   AltName: Full=Outer dense fiber protein 3-like protein 3;
GN   Name=ODF3B; Synonyms=ODF3L3;
//
ID   ODFP1_HUMAN             Reviewed;         250 AA.
AC   Q14990; Q3SX72;
DE   RecName: Full=Outer dense fiber protein 1;
GN   Name=ODF1; Synonyms=ODFP;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   ODFP2_HUMAN             Reviewed;         829 AA.
AC   Q5BJF6; B1AND3; B4DRK4; B4DX73; B4DZ02; E7EWL2; F5H6J4; O14721;
AC   O60631; Q1W2J6; Q6UN26; Q7Z5I6; Q96FN2;
DE   RecName: Full=Outer dense fiber protein 2;
DE   AltName: Full=Cenexin;
DE   AltName: Full=Outer dense fiber of sperm tails protein 2;
GN   Name=ODF2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   ODFP4_HUMAN             Reviewed;         257 AA.
AC   Q2M2E3; Q8J021;
DE   RecName: Full=Outer dense fiber protein 4;
DE   AltName: Full=Outer dense fiber of sperm tails protein 4;
DE   AltName: Full=Testis-specific protein oppo 1;
DE            Short=hOPPO1;
GN   Name=ODF4; Synonyms=OPPO1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   ODO1_HUMAN              Reviewed;        1023 AA.
AC   Q02218; B4E2U9; D3DVL0; E9PBM1; Q96DD3; Q9UDX0;
DE   RecName: Full=2-oxoglutarate dehydrogenase, mitochondrial;
DE            EC=1.2.4.2;
DE   AltName: Full=2-oxoglutarate dehydrogenase complex component E1;
DE            Short=OGDC-E1;
DE   AltName: Full=Alpha-ketoglutarate dehydrogenase;
DE   Flags: Precursor;
GN   Name=OGDH;
DR   GO; GO:0034602; F:oxoglutarate dehydrogenase (NAD+) activity; IEA:Ensembl.
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0021695; P:cerebellar cortex development; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; ISS:UniProtKB.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0006734; P:NADH metabolic process; IEA:Ensembl.
DR   GO; GO:0061034; P:olfactory bulb mitral cell layer development; IEA:Ensembl.
DR   GO; GO:0021860; P:pyramidal neuron development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
DR   GO; GO:0006104; P:succinyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IEA:Ensembl.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   ODO2_HUMAN              Reviewed;         453 AA.
AC   P36957; Q7LDY7; Q9BQ32;
DE   RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial;
DE            EC=2.3.1.61;
DE   AltName: Full=2-oxoglutarate dehydrogenase complex component E2;
DE            Short=OGDC-E2;
DE   AltName: Full=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex;
DE   AltName: Full=E2K;
DE   Flags: Precursor;
GN   Name=DLST; Synonyms=DLTS;
DR   GO; GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0033512; P:L-lysine catabolic process to acetyl-CoA via saccharopine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006554; P:lysine catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   ODP2_HUMAN              Reviewed;         647 AA.
AC   P10515; Q16783; Q53EP3;
DE   RecName: Full=Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial;
DE            EC=2.3.1.12;
DE   AltName: Full=70 kDa mitochondrial autoantigen of primary biliary cirrhosis;
DE            Short=PBC;
DE   AltName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex;
DE   AltName: Full=M2 antigen complex 70 kDa subunit;
DE   AltName: Full=Pyruvate dehydrogenase complex component E2;
DE            Short=PDC-E2;
DE            Short=PDCE2;
DE   Flags: Precursor;
GN   Name=DLAT; Synonyms=DLTA;
DR   GO; GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
//
ID   ODPAT_HUMAN             Reviewed;         388 AA.
AC   P29803; B2R9Q3; Q0VDI5; Q4VC02; Q6NXQ1;
DE   RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial;
DE            EC=1.2.4.1;
DE   AltName: Full=PDHE1-A type II;
DE   Flags: Precursor;
GN   Name=PDHA2; Synonyms=PDHAL;
DR   GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IDA:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006096; P:glycolytic process; IEA:InterPro.
DR   GO; GO:0006090; P:pyruvate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
//
ID   ODPA_HUMAN              Reviewed;         390 AA.
AC   P08559; A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; Q53H41; Q5JPT8; Q9NP12;
AC   Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5;
DE   RecName: Full=Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial;
DE            EC=1.2.4.1;
DE   AltName: Full=PDHE1-A type I;
DE   Flags: Precursor;
GN   Name=PDHA1; Synonyms=PHE1A;
DR   GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004738; F:pyruvate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006096; P:glycolytic process; IEA:InterPro.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IDA:UniProtKB.
//
ID   ODPB_HUMAN              Reviewed;         359 AA.
AC   P11177; B2R7L0; B4DDD7; Q6FH45; Q9BQ27; Q9UFK3;
DE   RecName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial;
DE            Short=PDHE1-B;
DE            EC=1.2.4.1;
DE   Flags: Precursor;
GN   Name=PDHB; Synonyms=PHE1B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; TAS:ProtInc.
DR   GO; GO:0004738; F:pyruvate dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IDA:UniProtKB.
//
ID   ODPX_HUMAN              Reviewed;         501 AA.
AC   O00330; B4DW62; D3DR11; E9PB14; E9PBP7; O60221; Q96FV8; Q99783;
DE   RecName: Full=Pyruvate dehydrogenase protein X component, mitochondrial;
DE   AltName: Full=Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex;
DE   AltName: Full=E3-binding protein;
DE            Short=E3BP;
DE   AltName: Full=Lipoyl-containing pyruvate dehydrogenase complex component X;
DE   AltName: Full=proX;
DE   Flags: Precursor;
GN   Name=PDHX; Synonyms=PDX1;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ODR4_HUMAN              Reviewed;         454 AA.
AC   Q5SWX8; B4DNY0; E9PFR7; Q19CC6; Q8WYB6; Q9BTS2; Q9H6A6; Q9NX06;
DE   RecName: Full=Protein odr-4 homolog;
DE            Short=hODR-4;
DE   AltName: Full=LAG1-interacting protein;
DE   AltName: Full=Transactivated by transforming growth factor beta protein 1;
GN   Name=ODR4; Synonyms=C1orf27, TTG1, TTG1A;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   OFD1_HUMAN              Reviewed;        1012 AA.
AC   O75665; B9ZVU5; O75666; Q4VAK4;
DE   RecName: Full=Oral-facial-digital syndrome 1 protein;
DE   AltName: Full=Protein 71-7A;
GN   Name=OFD1; Synonyms=CXorf5;
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   OFCC1_HUMAN             Reviewed;         231 AA.
AC   Q8IZS5; Q7Z2X5; Q8IUL6; Q8IUM1; Q8IZR9; Q8IZS1; Q8IZS3;
DE   RecName: Full=Orofacial cleft 1 candidate gene 1 protein;
DE   AltName: Full=Orofacial clefting chromosomal breakpoint region candidate 1 protein;
GN   Name=OFCC1; Synonyms=MRDS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   OFUT1_HUMAN             Reviewed;         388 AA.
AC   Q9H488; A8K4R8; E1P5M4; Q14685; Q5W185; Q9BW76;
DE   RecName: Full=GDP-fucose protein O-fucosyltransferase 1;
DE            EC=2.4.1.221;
DE   AltName: Full=Peptide-O-fucosyltransferase 1;
DE            Short=O-FucT-1;
DE   Flags: Precursor;
GN   Name=POFUT1; Synonyms=FUT12, KIAA0180;
DR   GO; GO:0008417; F:fucosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046922; F:peptide-O-fucosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; NAS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:UniProtKB.
DR   GO; GO:0036066; P:protein O-linked fucosylation; IDA:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   OFUT2_HUMAN             Reviewed;         429 AA.
AC   Q9Y2G5; Q6PJV1; Q7Z4N0; Q8WWU6; Q9BQS4; Q9BQS5; Q9UFY3;
DE   RecName: Full=GDP-fucose protein O-fucosyltransferase 2;
DE            EC=2.4.1.221;
DE   AltName: Full=Peptide-O-fucosyltransferase 2;
DE            Short=O-FucT-2;
DE   Flags: Precursor;
GN   Name=POFUT2; Synonyms=C21orf80, FUT13, KIAA0958;
DR   GO; GO:0046922; F:peptide-O-fucosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0036066; P:protein O-linked fucosylation; IDA:UniProtKB.
DR   GO; GO:0010717; P:regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0051046; P:regulation of secretion; IDA:UniProtKB.
//
ID   OGDHL_HUMAN             Reviewed;        1010 AA.
AC   Q9ULD0; A8K2G1; B4DKG2; B4E193; Q8TAN9; Q9NVA0;
DE   RecName: Full=2-oxoglutarate dehydrogenase-like, mitochondrial;
DE            EC=1.2.4.-;
DE   AltName: Full=2-oxoglutarate dehydrogenase complex component E1-like;
DE            Short=OGDC-E1-like;
DE   AltName: Full=Alpha-ketoglutarate dehydrogenase-like;
DE   Flags: Precursor;
GN   Name=OGDHL; Synonyms=KIAA1290;
DR   GO; GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
//
ID   OGFD1_HUMAN             Reviewed;         542 AA.
AC   Q8N543; H3BUQ2; Q9H7U5; Q9H9J9; Q9HA87; Q9HCG0; Q9NVB6;
DE   RecName: Full=Prolyl 3-hydroxylase OGFOD1;
DE            EC=1.14.11.-;
DE   AltName: Full=2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1;
DE   AltName: Full=Termination and polyadenylation 1 homolog;
GN   Name=OGFOD1; Synonyms=KIAA1612, TPA1;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
DR   GO; GO:0031544; F:peptidyl-proline 3-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0031543; F:peptidyl-proline dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0019511; P:peptidyl-proline hydroxylation; IDA:GOC.
DR   GO; GO:0018126; P:protein hydroxylation; IDA:UniProtKB.
DR   GO; GO:0006449; P:regulation of translational termination; IMP:UniProtKB.
DR   GO; GO:0034063; P:stress granule assembly; IMP:UniProtKB.
//
ID   OGFD2_HUMAN             Reviewed;         350 AA.
AC   Q6N063; B3KT24; Q4KN13; Q6N023; Q9H8K6;
DE   RecName: Full=2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2;
DE            EC=1.14.11.-;
GN   Name=OGFOD2;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
//
ID   OGFD3_HUMAN             Reviewed;         319 AA.
AC   Q6PK18; C9JDC8; Q8IZ37; Q9H6J2;
DE   RecName: Full=2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3;
DE            EC=1.14.11.-;
GN   Name=OGFOD3; Synonyms=C17orf101;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
//
ID   OGFR_HUMAN              Reviewed;         677 AA.
AC   Q9NZT2; O96029; Q4VXW5; Q96CM2; Q9BQW1; Q9H4H0; Q9H7J5; Q9NZT3;
AC   Q9NZT4;
DE   RecName: Full=Opioid growth factor receptor;
DE            Short=OGFr;
DE   AltName: Full=Protein 7-60;
DE   AltName: Full=Zeta-type opioid receptor;
GN   Name=OGFR;
DR   GO; GO:0004985; F:opioid receptor activity; NAS:UniProtKB.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; NAS:GOC.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   OGG1_HUMAN              Reviewed;         345 AA.
AC   O15527; A8K1E3; O00390; O00670; O00705; O14876; O95488; P78554;
AC   Q9BW42; Q9UIK0; Q9UIK1; Q9UIK2; Q9UL34; Q9Y2C0; Q9Y2C1; Q9Y6C3;
AC   Q9Y6C4;
DE   RecName: Full=N-glycosylase/DNA lyase;
DE   Includes:
DE     RecName: Full=8-oxoguanine DNA glycosylase;
DE              EC=3.2.2.-;
DE   Includes:
DE     RecName: Full=DNA-(apurinic or apyrimidinic site) lyase;
DE              Short=AP lyase;
DE              EC=4.2.99.18;
GN   Name=OGG1; Synonyms=MMH, MUTM, OGH1;
DR   GO; GO:0034039; F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; IEA:Ensembl.
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0004519; F:endonuclease activity; TAS:ProtInc.
DR   GO; GO:0008534; F:oxidized purine nucleobase lesion DNA N-glycosylase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0045007; P:depurination; TAS:Reactome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; TAS:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0033158; P:regulation of protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; IDA:UniProtKB.
//
ID   OGR1_HUMAN              Reviewed;         365 AA.
AC   Q15743; Q13334; Q4VBB4; Q6IX34;
DE   RecName: Full=Ovarian cancer G-protein coupled receptor 1;
DE            Short=OGR-1;
DE   AltName: Full=G-protein coupled receptor 68;
DE   AltName: Full=GPR12A;
DE   AltName: Full=Sphingosylphosphorylcholine receptor;
GN   Name=GPR68; Synonyms=OGR1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
//
ID   OGRL1_HUMAN             Reviewed;         451 AA.
AC   Q5TC84; Q2TAC1; Q8NEQ4; Q9H7B5;
DE   RecName: Full=Opioid growth factor receptor-like protein 1;
GN   Name=OGFRL1;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
//
ID   OGT1_HUMAN              Reviewed;        1046 AA.
AC   O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57;
DE   RecName: Full=UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit;
DE            EC=2.4.1.255;
DE   AltName: Full=O-GlcNAc transferase subunit p110;
DE   AltName: Full=O-linked N-acetylglucosamine transferase 110 kDa subunit;
DE            Short=OGT;
GN   Name=OGT;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008047; F:enzyme activator activity; IDA:BHF-UCL.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016262; F:protein N-acetylglucosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0097363; F:protein O-GlcNAc transferase activity; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0061087; P:positive regulation of histone H3-K27 methylation; IMP:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IDA:BHF-UCL.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0090526; P:regulation of gluconeogenesis involved in cellular glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006110; P:regulation of glycolytic process; IDA:UniProtKB.
DR   GO; GO:0046626; P:regulation of insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035020; P:regulation of Rac protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; IDA:UniProtKB.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   OIT3_HUMAN              Reviewed;         545 AA.
AC   Q8WWZ8; A0AVP3; Q8N1M8;
DE   RecName: Full=Oncoprotein-induced transcript 3 protein;
DE   AltName: Full=Liver-specific zona pellucida domain-containing protein;
DE   Flags: Precursor;
GN   Name=OIT3; Synonyms=LZP; ORFNames=UNQ826/PRO1753;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   OLA1_HUMAN              Reviewed;         396 AA.
AC   Q9NTK5; D7EHM2; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9P1D3; Q9UNY9;
AC   Q9Y6G4;
DE   RecName: Full=Obg-like ATPase 1;
DE   AltName: Full=DNA damage-regulated overexpressed in cancer 45;
DE            Short=DOC45;
DE   AltName: Full=GTP-binding protein 9;
GN   Name=OLA1; Synonyms=GTPBP9; ORFNames=PRO2455, PTD004;
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0016887; F:ATPase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043022; F:ribosome binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:HGNC.
//
ID   OLFL1_HUMAN             Reviewed;         402 AA.
AC   Q6UWY5; B4DP03; Q569G4;
DE   RecName: Full=Olfactomedin-like protein 1;
DE   Flags: Precursor;
GN   Name=OLFML1; ORFNames=UNQ564/PRO1126;
//
ID   OLFL3_HUMAN             Reviewed;         406 AA.
AC   Q9NRN5; Q53FR1; Q53HV9; Q5SQL6; Q69AX9; Q8NBJ2;
DE   RecName: Full=Olfactomedin-like protein 3;
DE   AltName: Full=HNOEL-iso;
DE   AltName: Full=hOLF44;
DE   Flags: Precursor;
GN   Name=OLFML3; ORFNames=PSEC0035, PSEC0173, PSEC0244, UNQ663/PRO1294;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   OLFM4_HUMAN             Reviewed;         510 AA.
AC   Q6UX06; O95362; Q5VWG0; Q86T22;
DE   RecName: Full=Olfactomedin-4;
DE            Short=OLM4;
DE   AltName: Full=Antiapoptotic protein GW112;
DE   AltName: Full=G-CSF-stimulated clone 1 protein;
DE            Short=hGC-1;
DE   AltName: Full=hOLfD;
DE   Flags: Precursor;
GN   Name=OLFM4; Synonyms=GW112; ORFNames=UNQ362/PRO698;
DR   GO; GO:0045296; F:cadherin binding; IMP:UniProt.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IMP:UniProt.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0050777; P:negative regulation of immune response; IEA:Ensembl.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IDA:UniProt.
DR   GO; GO:0051260; P:protein homooligomerization; IMP:UniProt.
//
ID   OLIG1_HUMAN             Reviewed;         271 AA.
AC   Q8TAK6; Q7RTS0;
DE   RecName: Full=Oligodendrocyte transcription factor 1;
DE            Short=Oligo1;
DE   AltName: Full=Class B basic helix-loop-helix protein 6;
DE            Short=bHLHb6;
DE   AltName: Full=Class E basic helix-loop-helix protein 21;
DE            Short=bHLHe21;
GN   Name=OLIG1; Synonyms=BHLHB6, BHLHE21;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   OLM2A_HUMAN             Reviewed;         652 AA.
AC   Q68BL7; Q5JTM5; Q5JTM6; Q6UXW1; Q7Z5V3;
DE   RecName: Full=Olfactomedin-like protein 2A;
DE   AltName: Full=Photomedin-1;
DE   Flags: Precursor;
GN   Name=OLFML2A; ORFNames=UNQ9394/PRO34319;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
//
ID   OLIG3_HUMAN             Reviewed;         272 AA.
AC   Q7RTU3; Q8N8Q0;
DE   RecName: Full=Oligodendrocyte transcription factor 3;
DE            Short=Oligo3;
DE   AltName: Full=Class B basic helix-loop-helix protein 7;
DE            Short=bHLHb7;
DE   AltName: Full=Class E basic helix-loop-helix protein 20;
DE            Short=bHLHe20;
GN   Name=OLIG3; Synonyms=BHLHB7, BHLHE20;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0021520; P:spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0097476; P:spinal cord motor neuron migration; IEA:Ensembl.
//
ID   OLIG2_HUMAN             Reviewed;         323 AA.
AC   Q13516; B3KRF3; Q05BP9; Q49AL3; Q86X04; Q9NZ14;
DE   RecName: Full=Oligodendrocyte transcription factor 2;
DE            Short=Oligo2;
DE   AltName: Full=Class B basic helix-loop-helix protein 1;
DE            Short=bHLHb1;
DE   AltName: Full=Class E basic helix-loop-helix protein 19;
DE            Short=bHLHe19;
DE   AltName: Full=Protein kinase C-binding protein 2;
DE   AltName: Full=Protein kinase C-binding protein RACK17;
GN   Name=OLIG2; Synonyms=BHLHB1, BHLHE19, PRKCBP2, RACK17;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021530; P:spinal cord oligodendrocyte cell fate specification; IEA:Ensembl.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
//
ID   OLM2B_HUMAN             Reviewed;         750 AA.
AC   Q68BL8; B7ZA39; Q5VU96; Q6NX46; Q86X11; Q9Y3X6;
DE   RecName: Full=Olfactomedin-like protein 2B;
DE   AltName: Full=Photomedin-2;
DE   Flags: Precursor;
GN   Name=OLFML2B;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
//
ID   OLR1_HUMAN              Reviewed;         273 AA.
AC   P78380; A8K7V9; B4DI48; G3V1I4; Q2PP00; Q7Z484;
DE   RecName: Full=Oxidized low-density lipoprotein receptor 1;
DE            Short=Ox-LDL receptor 1;
DE   AltName: Full=C-type lectin domain family 8 member A;
DE   AltName: Full=Lectin-like oxidized LDL receptor 1;
DE            Short=LOX-1;
DE            Short=Lectin-like oxLDL receptor 1;
DE            Short=hLOX-1;
DE   AltName: Full=Lectin-type oxidized LDL receptor 1;
DE   Contains:
DE     RecName: Full=Oxidized low-density lipoprotein receptor 1, soluble form;
GN   Name=OLR1; Synonyms=CLEC8A, LOX1;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
//
ID   OMA1_HUMAN              Reviewed;         524 AA.
AC   Q96E52; D3DQ54; Q5T3G6; Q5T3G7; Q5T3G8; Q5T3G9; Q5T3H0; Q8NBB3;
DE   RecName: Full=Metalloendopeptidase OMA1, mitochondrial;
DE            EC=3.4.24.-;
DE   AltName: Full=Metalloprotease-related protein 1;
DE            Short=MPRP-1;
DE   AltName: Full=Overlapping with the m-AAA protease 1 homolog;
DE   Flags: Precursor;
GN   Name=OMA1; Synonyms=MPRP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0042407; P:cristae formation; IEA:Ensembl.
DR   GO; GO:0002024; P:diet induced thermogenesis; IMP:UniProtKB.
DR   GO; GO:0097009; P:energy homeostasis; IMP:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; IMP:UniProtKB.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0034982; P:mitochondrial protein processing; IEA:Ensembl.
DR   GO; GO:0010637; P:negative regulation of mitochondrial fusion; IMP:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
//
ID   OMD_HUMAN               Reviewed;         421 AA.
AC   Q99983; Q5TBF4;
DE   RecName: Full=Osteomodulin;
DE   AltName: Full=Keratan sulfate proteoglycan osteomodulin;
DE            Short=KSPG osteomodulin;
DE   AltName: Full=Osteoadherin;
DE            Short=OSAD;
DE   Flags: Precursor;
GN   Name=OMD; Synonyms=SLRR2C; ORFNames=UNQ190/PRO216;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   OMGP_HUMAN              Reviewed;         440 AA.
AC   P23515; E1P659;
DE   RecName: Full=Oligodendrocyte-myelin glycoprotein;
DE   Flags: Precursor;
GN   Name=OMG; Synonyms=OMGP;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0031102; P:neuron projection regeneration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048683; P:regulation of collateral sprouting of intact axon in response to injury; IEA:Ensembl.
//
ID   OMP_HUMAN               Reviewed;         163 AA.
AC   P47874; Q562G2;
DE   RecName: Full=Olfactory marker protein;
DE   AltName: Full=Olfactory neuronal-specific protein;
GN   Name=OMP;
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   ONCM_HUMAN              Reviewed;         252 AA.
AC   P13725; Q6FHP8; Q9UCP6;
DE   RecName: Full=Oncostatin-M;
DE            Short=OSM;
DE   Flags: Precursor;
GN   Name=OSM;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0005147; F:oncostatin-M receptor binding; IPI:BHF-UCL.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IDA:MGI.
DR   GO; GO:0045835; P:negative regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IC:BHF-UCL.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0042508; P:tyrosine phosphorylation of Stat1 protein; IEA:Ensembl.
DR   GO; GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IEA:Ensembl.
DR   GO; GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IEA:Ensembl.
//
ID   ONCO_HUMAN              Reviewed;         109 AA.
AC   P0CE72; B9EJH7; P32930; Q6ISI5; Q75MW0;
DE   RecName: Full=Oncomodulin-1;
DE            Short=OM;
DE   AltName: Full=Parvalbumin beta;
GN   Name=OCM; Synonyms=OCM1, OCMN;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
//
ID   ONEC2_HUMAN             Reviewed;         504 AA.
AC   O95948;
DE   RecName: Full=One cut domain family member 2;
DE   AltName: Full=Hepatocyte nuclear factor 6-beta;
DE            Short=HNF-6-beta;
DE   AltName: Full=One cut homeobox 2;
DE   AltName: Full=Transcription factor ONECUT-2;
DE            Short=OC-2;
GN   Name=ONECUT2; Synonyms=HNF6B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0002064; P:epithelial cell development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ONEC3_HUMAN             Reviewed;         494 AA.
AC   O60422; A8MZM7;
DE   RecName: Full=One cut domain family member 3;
DE   AltName: Full=One cut homeobox 3;
DE   AltName: Full=Transcription factor ONECUT-3;
DE            Short=OC-3;
GN   Name=ONECUT3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   OOEP_HUMAN              Reviewed;         149 AA.
AC   A6NGQ2; A6NIN5; A9UIB7;
DE   RecName: Full=Oocyte-expressed protein homolog;
DE   AltName: Full=KH homology domain-containing protein 2;
DE   AltName: Full=Oocyte- and embryo-specific protein 19;
DE            Short=hOEP19;
GN   Name=OOEP; Synonyms=C6orf156, KHDC2, OEP19;
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0035088; P:establishment or maintenance of apical/basal cell polarity; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
//
ID   OOSP2_HUMAN             Reviewed;         158 AA.
AC   Q86WS3; E9PJA4; Q8N9U6;
DE   RecName: Full=Oocyte-secreted protein 2;
DE   AltName: Full=Placenta-specific 1-like protein;
DE   AltName: Full=Protein TMEM122;
DE   Flags: Precursor;
GN   Name=OOSP2; Synonyms=PLAC1L, TMEM122;
//
ID   OOSP1_HUMAN             Reviewed;         123 AA.
AC   A8MZH6;
DE   RecName: Full=Putative oocyte-secreted protein 1 homolog;
DE   Flags: Precursor;
GN   Name=OOSP1;
//
ID   OPA1_HUMAN              Reviewed;         960 AA.
AC   O60313; D3DNW4;
DE   RecName: Full=Dynamin-like 120 kDa protein, mitochondrial;
DE            EC=3.6.5.5;
DE   AltName: Full=Optic atrophy protein 1;
DE   Contains:
DE     RecName: Full=Dynamin-like 120 kDa protein, form S1;
DE   Flags: Precursor;
GN   Name=OPA1; Synonyms=KIAA0567;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0019896; P:axon transport of mitochondrion; TAS:UniProtKB.
DR   GO; GO:0090398; P:cellular senescence; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007007; P:inner mitochondrial membrane organization; IDA:UniProtKB.
DR   GO; GO:0000266; P:mitochondrial fission; TAS:UniProtKB.
DR   GO; GO:0008053; P:mitochondrial fusion; IDA:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; NAS:UniProtKB.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   OPA3_HUMAN              Reviewed;         179 AA.
AC   Q9H6K4; Q6P384; Q8N784;
DE   RecName: Full=Optic atrophy 3 protein;
GN   Name=OPA3;
DR   GO; GO:0040007; P:growth; IEA:Ensembl.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   OPALI_HUMAN             Reviewed;         141 AA.
AC   Q96PE5; A8MX69; A8MYG4; B4DK96; B4DKH0; Q5W102;
DE   RecName: Full=Opalin;
DE   AltName: Full=Oligodendrocytic myelin paranodal and inner loop protein;
DE   AltName: Full=Transmembrane protein 10;
GN   Name=OPALIN; Synonyms=HTMP10, TMEM10;
//
ID   OPCM_HUMAN              Reviewed;         345 AA.
AC   Q14982; B2CZX2; B7ZLQ1; Q17RN7; Q7Z3W6;
DE   RecName: Full=Opioid-binding protein/cell adhesion molecule;
DE            Short=OBCAM;
DE            Short=OPCML;
DE            Short=Opioid-binding cell adhesion molecule;
DE   AltName: Full=IgLON family member 1;
DE   Flags: Precursor;
GN   Name=OPCML; Synonyms=IGLON1, OBCAM;
DR   GO; GO:0004985; F:opioid receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0008038; P:neuron recognition; TAS:ProtInc.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; TAS:GOC.
//
ID   OPHN1_HUMAN             Reviewed;         802 AA.
AC   O60890; B9EIP8; Q5JQ81; Q8WX47;
DE   RecName: Full=Oligophrenin-1;
GN   Name=OPHN1;
DR   GO; GO:0005543; F:phospholipid binding; IDA:FlyBase.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:Ensembl.
//
ID   OPN3_HUMAN              Reviewed;         402 AA.
AC   Q9H1Y3; Q8IX08; Q9Y344;
DE   RecName: Full=Opsin-3;
DE   AltName: Full=Encephalopsin;
DE   AltName: Full=Panopsin;
GN   Name=OPN3; Synonyms=ECPN;
DR   GO; GO:0008020; F:G-protein coupled photoreceptor activity; NAS:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0009881; F:photoreceptor activity; NAS:UniProtKB.
DR   GO; GO:0009583; P:detection of light stimulus; NAS:UniProtKB.
DR   GO; GO:0009584; P:detection of visible light; NAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007602; P:phototransduction; NAS:UniProtKB.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0042752; P:regulation of circadian rhythm; NAS:UniProtKB.
//
ID   OPLA_HUMAN              Reviewed;        1288 AA.
AC   O14841; A5PKY8; Q75W65; Q9Y4Q0;
DE   RecName: Full=5-oxoprolinase;
DE            EC=3.5.2.9;
DE   AltName: Full=5-oxo-L-prolinase;
DE            Short=5-OPase;
DE   AltName: Full=Pyroglutamase;
GN   Name=OPLAH;
DR   GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; TAS:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006750; P:glutathione biosynthetic process; TAS:Reactome.
DR   GO; GO:1901687; P:glutathione derivative biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   OPN4_HUMAN              Reviewed;         478 AA.
AC   Q9UHM6; B7ZLB3; Q14D01; Q2PP22; Q8NGQ9;
DE   RecName: Full=Melanopsin;
DE   AltName: Full=Opsin-4;
GN   Name=OPN4; Synonyms=MOP;
DR   GO; GO:0005502; F:11-cis retinal binding; IDA:UniProtKB.
DR   GO; GO:0008020; F:G-protein coupled photoreceptor activity; IDA:UniProtKB.
DR   GO; GO:0007602; P:phototransduction; IDA:UniProtKB.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
//
ID   OPN5_HUMAN              Reviewed;         354 AA.
AC   Q6U736; A0AV33; Q5T5B9; Q5T886; Q7Z603; Q86SL5;
DE   RecName: Full=Opsin-5;
DE   AltName: Full=G-protein coupled receptor 136;
DE   AltName: Full=G-protein coupled receptor PGR12;
DE   AltName: Full=Neuropsin;
DE   AltName: Full=Transmembrane protein 13;
GN   Name=OPN5; Synonyms=GPR136, PGR12, TMEM13;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:InterPro.
//
ID   OPRD_HUMAN              Reviewed;         372 AA.
AC   P41143; B5B0B8;
DE   RecName: Full=Delta-type opioid receptor;
DE            Short=D-OR-1;
DE            Short=DOR-1;
GN   Name=OPRD1; Synonyms=OPRD;
DR   GuidetoPHARMACOLOGY; 317; -.
DR   GO; GO:0038046; F:enkephalin receptor activity; IMP:UniProtKB.
DR   GO; GO:0004985; F:opioid receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:Ensembl.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
//
ID   OPRK_HUMAN              Reviewed;         380 AA.
AC   P41145; E5RHC9; Q499G4;
DE   RecName: Full=Kappa-type opioid receptor;
DE            Short=K-OR-1;
DE            Short=KOR-1;
GN   Name=OPRK1; Synonyms=OPRK;
DR   GuidetoPHARMACOLOGY; 318; -.
DR   GO; GO:0038048; F:dynorphin receptor activity; IDA:UniProtKB.
DR   GO; GO:0004985; F:opioid receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0031635; P:adenylate cyclase-inhibiting opioid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007610; P:behavior; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0046877; P:regulation of saliva secretion; ISS:UniProtKB.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   OPRM_HUMAN              Reviewed;         400 AA.
AC   P35372; B0FXJ1; B2R9S7; B8Q1L7; B8Q1L8; B8Q1L9; E7EWZ3; G8XRH6;
AC   G8XRH8; Q12930; Q4VWM1; Q4VWM2; Q4VWM3; Q4VWM4; Q4VWM6; Q4VWX6;
AC   Q5TDA1; Q6UPP1; Q6UQ80; Q7Z2D8; Q86V80; Q8IWW3; Q8IWW4; Q9UCZ4;
AC   Q9UN57;
DE   RecName: Full=Mu-type opioid receptor;
DE            Short=M-OR-1;
DE            Short=MOR-1;
DE   AltName: Full=Mu opiate receptor;
DE   AltName: Full=Mu opioid receptor;
DE            Short=MOP;
DE            Short=hMOP;
GN   Name=OPRM1; Synonyms=MOR1;
DR   GuidetoPHARMACOLOGY; 319; -.
DR   GO; GO:0004979; F:beta-endorphin receptor activity; IMP:UniProtKB.
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; IDA:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; ISS:UniProtKB.
DR   GO; GO:0038047; F:morphine receptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048149; P:behavioral response to ethanol; IMP:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; ISS:GOC.
DR   GO; GO:0033554; P:cellular response to stress; IMP:UniProtKB.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; ISS:UniProtKB.
DR   GO; GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0061358; P:negative regulation of Wnt protein secretion; IMP:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IMP:GOC.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
DR   GO; GO:0007600; P:sensory perception; NAS:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
//
ID   OPRX_HUMAN              Reviewed;         370 AA.
AC   P41146; Q8TD34; Q8WYH9; Q9H4K4;
DE   RecName: Full=Nociceptin receptor;
DE   AltName: Full=Kappa-type 3 opioid receptor;
DE            Short=KOR-3;
DE   AltName: Full=Orphanin FQ receptor;
GN   Name=OPRL1; Synonyms=OOR, ORL1;
DR   GuidetoPHARMACOLOGY; 320; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IMP:UniProtKB.
DR   GO; GO:0001626; F:nociceptin receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007610; P:behavior; IEA:UniProtKB-KW.
DR   GO; GO:0038003; P:opioid receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IGI:UniProtKB.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:UniProtKB.
//
ID   OPSB_HUMAN              Reviewed;         348 AA.
AC   P03999; Q13877;
DE   RecName: Full=Short-wave-sensitive opsin 1;
DE   AltName: Full=Blue cone photoreceptor pigment;
DE   AltName: Full=Blue-sensitive opsin;
DE            Short=BOP;
GN   Name=OPN1SW; Synonyms=BCP;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007602; P:phototransduction; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   OPSD_HUMAN              Reviewed;         348 AA.
AC   P08100; Q16414; Q2M249;
DE   RecName: Full=Rhodopsin;
DE   AltName: Full=Opsin-2;
GN   Name=RHO; Synonyms=OPN2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016918; F:retinal binding; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0009585; P:red, far-red light phototransduction; IEA:Ensembl.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   OPSG_HUMAN              Reviewed;         364 AA.
AC   P04001;
DE   RecName: Full=Medium-wave-sensitive opsin 1;
DE   AltName: Full=Green cone photoreceptor pigment;
DE   AltName: Full=Green-sensitive opsin;
DE            Short=GOP;
GN   Name=OPN1MW; Synonyms=GCP;
GN   and
GN   Name=OPN1MW2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   OPSR_HUMAN              Reviewed;         364 AA.
AC   P04000;
DE   RecName: Full=Long-wave-sensitive opsin 1;
DE   AltName: Full=Red cone photoreceptor pigment;
DE   AltName: Full=Red-sensitive opsin;
DE            Short=ROP;
GN   Name=OPN1LW; Synonyms=RCP;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009881; F:photoreceptor activity; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   OPSX_HUMAN              Reviewed;         337 AA.
AC   O14718; A1A4V2; Q7RTS4;
DE   RecName: Full=Visual pigment-like receptor peropsin;
GN   Name=RRH;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   OPTN_HUMAN              Reviewed;         577 AA.
AC   Q96CV9; B3KP00; D3DRS4; D3DRS8; Q5T672; Q5T673; Q5T674; Q5T675;
AC   Q7LDL9; Q8N562; Q9UET9; Q9UEV4; Q9Y218;
DE   RecName: Full=Optineurin;
DE   AltName: Full=E3-14.7K-interacting protein;
DE   AltName: Full=FIP-2;
DE   AltName: Full=Huntingtin yeast partner L;
DE   AltName: Full=Huntingtin-interacting protein 7;
DE            Short=HIP-7;
DE   AltName: Full=Huntingtin-interacting protein L;
DE   AltName: Full=NEMO-related protein;
DE   AltName: Full=Optic neuropathy-inducing protein;
DE   AltName: Full=Transcription factor IIIA-interacting protein;
DE            Short=TFIIIA-IntP;
GN   Name=OPTN; Synonyms=FIP2, GLC1E, HIP7, HYPL, NRP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; TAS:ProtInc.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0090161; P:Golgi ribbon formation; IDA:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000042; P:protein targeting to Golgi; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   OPT_HUMAN               Reviewed;         332 AA.
AC   Q9UBM4; Q5T2G4;
DE   RecName: Full=Opticin;
DE   AltName: Full=Oculoglycan;
DE   Flags: Precursor;
GN   Name=OPTC; Synonyms=OPT;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
//
ID   OR1A1_HUMAN             Reviewed;         309 AA.
AC   Q9P1Q5; A5D914; Q6IFM1; Q6NTA9; Q96R87;
DE   RecName: Full=Olfactory receptor 1A1;
DE   AltName: Full=Olfactory receptor 17-7;
DE            Short=OR17-7;
DE   AltName: Full=Olfactory receptor OR17-11;
GN   Name=OR1A1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1A2_HUMAN             Reviewed;         309 AA.
AC   Q9Y585; Q3KPH3; Q6IFM0; Q6NTD8; Q96R86;
DE   RecName: Full=Olfactory receptor 1A2;
DE   AltName: Full=Olfactory receptor 17-6;
DE            Short=OR17-6;
DE   AltName: Full=Olfactory receptor OR17-10;
GN   Name=OR1A2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
//
ID   OR1B1_HUMAN             Reviewed;         318 AA.
AC   Q8NGR6; Q6IFN3;
DE   RecName: Full=Olfactory receptor 1B1;
DE   AltName: Full=Olfactory receptor 9-B;
DE            Short=OR9-B;
DE   AltName: Full=Olfactory receptor OR9-26;
GN   Name=OR1B1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1C1_HUMAN             Reviewed;         314 AA.
AC   Q15619; B9EIR9; Q5VVD2; Q6IF97; Q8NGZ1; Q96R83;
DE   RecName: Full=Olfactory receptor 1C1;
DE   AltName: Full=Olfactory receptor OR1-42;
DE   AltName: Full=Olfactory receptor TPCR27;
GN   Name=OR1C1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR1D2_HUMAN             Reviewed;         312 AA.
AC   P34982; Q6IFL8; Q96RA4; Q9UM78;
DE   RecName: Full=Olfactory receptor 1D2;
DE   AltName: Full=Olfactory receptor 17-4;
DE            Short=OR17-4;
DE   AltName: Full=Olfactory receptor OR17-6;
DE   AltName: Full=Olfactory receptor-like protein HGMP07E;
GN   Name=OR1D2; Synonyms=OLFR1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004984; F:olfactory receptor activity; IDA:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; IDA:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.
DR   GO; GO:0007608; P:sensory perception of smell; TAS:ProtInc.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
//
ID   OR1D4_HUMAN             Reviewed;         311 AA.
AC   P47884; Q96RA5; Q9UM75;
DE   RecName: Full=Olfactory receptor 1D4;
DE   AltName: Full=Olfactory receptor 17-30;
DE            Short=OR17-30;
GN   Name=OR1D4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; TAS:ProtInc.
//
ID   OR1D5_HUMAN             Reviewed;         312 AA.
AC   P58170; Q96RA6;
DE   RecName: Full=Olfactory receptor 1D5;
DE   AltName: Full=Olfactory receptor 17-31;
DE            Short=OR17-31;
GN   Name=OR1D5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004984; F:olfactory receptor activity; TAS:ProtInc.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; TAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007608; P:sensory perception of smell; TAS:ProtInc.
//
ID   OR1E1_HUMAN             Reviewed;         314 AA.
AC   P30953; O43884; P47882; P47885; Q6IFA9; Q6IFM5; Q9UBJ1; Q9UM60;
DE   RecName: Full=Olfactory receptor 1E1;
DE   AltName: Full=Olfactory receptor 13-66;
DE            Short=OR13-66;
DE   AltName: Full=Olfactory receptor 17-2/17-32;
DE            Short=OR17-2;
DE            Short=OR17-32;
DE   AltName: Full=Olfactory receptor 1E5;
DE   AltName: Full=Olfactory receptor 1E6;
DE   AltName: Full=Olfactory receptor 5-85;
DE            Short=OR5-85;
DE   AltName: Full=Olfactory receptor OR17-18;
DE   AltName: Full=Olfactory receptor-like protein HGMP07I;
GN   Name=OR1E1; Synonyms=OR1E5, OR1E6, OR1E9P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR1E2_HUMAN             Reviewed;         323 AA.
AC   P47887; O43877; O95632; Q0VAD5; Q0VAD6; Q9UL13;
DE   RecName: Full=Olfactory receptor 1E2;
DE   AltName: Full=Olfactory receptor 17-93/17-135/17-136;
DE            Short=OR17-135;
DE            Short=OR17-136;
DE            Short=OR17-93;
DE   AltName: Full=Olfactory receptor 1E4;
GN   Name=OR1E2; Synonyms=OR1E4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   OR1E3_HUMAN             Reviewed;         343 AA.
AC   Q8WZA6;
DE   RecName: Full=Olfactory receptor 1E3;
DE   AltName: Full=Olfactory receptor 17-210;
DE            Short=OR17-210;
DE   AltName: Full=Olfactory receptor OR17-7;
GN   Name=OR1E3; Synonyms=OR1E3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1F1_HUMAN             Reviewed;         312 AA.
AC   O43749; O15246; Q6IFL5;
DE   RecName: Full=Olfactory receptor 1F1;
DE   AltName: Full=Olfactory receptor 16-35;
DE            Short=OR16-35;
DE   AltName: Full=Olfactory receptor 1F10;
DE   AltName: Full=Olfactory receptor 1F4;
DE   AltName: Full=Olfactory receptor 1F5;
DE   AltName: Full=Olfactory receptor 1F6;
DE   AltName: Full=Olfactory receptor 1F7;
DE   AltName: Full=Olfactory receptor 1F8;
DE   AltName: Full=Olfactory receptor 1F9;
DE   AltName: Full=Olfactory receptor OR16-4;
GN   Name=OR1F1;
GN   Synonyms=OLFMF, OR1F10, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   OR1F2_HUMAN             Reviewed;         312 AA.
AC   Q96R84;
DE   RecName: Full=Putative olfactory receptor 1F2;
DE   AltName: Full=OLFmf2;
GN   Name=OR1F2P; Synonyms=OR1F2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1FC_HUMAN             Reviewed;         337 AA.
AC   Q8NHA8;
DE   RecName: Full=Olfactory receptor 1F12;
DE   AltName: Full=Hs6M1-35P;
GN   Name=OR1F12; Synonyms=OR1F12P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1G1_HUMAN             Reviewed;         313 AA.
AC   P47890; Q4VBM1; Q6IFL9; Q9UM76;
DE   RecName: Full=Olfactory receptor 1G1;
DE   AltName: Full=Olfactory receptor 17-209;
DE            Short=OR17-209;
DE   AltName: Full=Olfactory receptor 1G2;
DE   AltName: Full=Olfactory receptor OR17-8;
GN   Name=OR1G1; Synonyms=OR1G2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   OR1I1_HUMAN             Reviewed;         355 AA.
AC   O60431; Q96R92;
DE   RecName: Full=Olfactory receptor 1I1;
DE   AltName: Full=Olfactory receptor 19-20;
DE            Short=OR19-20;
GN   Name=OR1I1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1J1_HUMAN             Reviewed;         322 AA.
AC   Q8NGS3; A3KFL8; Q6IF10; Q96R88;
DE   RecName: Full=Olfactory receptor 1J1;
DE   AltName: Full=Olfactory receptor OR9-18;
GN   Name=OR1J1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1J2_HUMAN             Reviewed;         313 AA.
AC   Q8NGS2; A3KFL9; Q6IF14; Q96R90; Q9NZP1;
DE   RecName: Full=Olfactory receptor 1J2;
DE   AltName: Full=HSA5;
DE   AltName: Full=HTPCRX15;
DE   AltName: Full=OST044;
DE   AltName: Full=Olfactory receptor 1J3;
DE   AltName: Full=Olfactory receptor 1J5;
DE   AltName: Full=Olfactory receptor OR9-19;
GN   Name=OR1J2; Synonyms=OR1J3, OR1J5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1J4_HUMAN             Reviewed;         313 AA.
AC   Q8NGS1; A3KFM0; Q6IEZ3; Q96R89;
DE   RecName: Full=Olfactory receptor 1J4;
DE   AltName: Full=HTPCRX01;
DE   AltName: Full=Olfactory receptor OR9-21;
GN   Name=OR1J4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1K1_HUMAN             Reviewed;         316 AA.
AC   Q8NGR3; B9EH41; Q4VXB7; Q96R23;
DE   RecName: Full=Olfactory receptor 1K1;
GN   Name=OR1K1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1L1_HUMAN             Reviewed;         360 AA.
AC   Q8NH94; Q5T7Z3; Q6IFN2;
DE   RecName: Full=Olfactory receptor 1L1;
DE   AltName: Full=Olfactory receptor 1L2;
DE   AltName: Full=Olfactory receptor 9-C;
DE            Short=OR9-C;
DE   AltName: Full=Olfactory receptor OR9-27;
GN   Name=OR1L1; Synonyms=OR1L2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1L3_HUMAN             Reviewed;         324 AA.
AC   Q8NH93; B2RNF4; Q6IFN1;
DE   RecName: Full=Olfactory receptor 1L3;
DE   AltName: Full=Olfactory receptor 9-D;
DE            Short=OR9-D;
DE   AltName: Full=Olfactory receptor OR9-28;
GN   Name=OR1L3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1L6_HUMAN             Reviewed;         347 AA.
AC   Q8NGR2; Q6IFM8; Q96R80;
DE   RecName: Full=Olfactory receptor 1L6;
DE   AltName: Full=Olfactory receptor 1L7;
DE   AltName: Full=Olfactory receptor OR9-30;
GN   Name=OR1L6; Synonyms=OR1L7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1L8_HUMAN             Reviewed;         309 AA.
AC   Q8NGR8; A3KFM3; B9EIR6; Q6IF15; Q96R79;
DE   RecName: Full=Olfactory receptor 1L8;
DE   AltName: Full=Olfactory receptor OR9-24;
GN   Name=OR1L8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1L4_HUMAN             Reviewed;         311 AA.
AC   Q8NGR5; Q6IFN0; Q96R81;
DE   RecName: Full=Olfactory receptor 1L4;
DE   AltName: Full=OST046;
DE   AltName: Full=Olfactory receptor 1L5;
DE   AltName: Full=Olfactory receptor 9-E;
DE            Short=OR9-E;
DE   AltName: Full=Olfactory receptor OR9-29;
GN   Name=OR1L4; Synonyms=OR1L5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1M1_HUMAN             Reviewed;         313 AA.
AC   Q8NGA1; B9EHA6; Q6IFJ3; Q96R91;
DE   RecName: Full=Olfactory receptor 1M1;
DE   AltName: Full=Olfactory receptor 19-6;
DE            Short=OR19-6;
DE   AltName: Full=Olfactory receptor OR19-5;
GN   Name=OR1M1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1N1_HUMAN             Reviewed;         311 AA.
AC   Q8NGS0; A3KFM1; O43870; Q6IF16; Q96R93;
DE   RecName: Full=Olfactory receptor 1N1;
DE   AltName: Full=Olfactory receptor 1-26;
DE            Short=OR1-26;
DE   AltName: Full=Olfactory receptor 1N3;
DE   AltName: Full=Olfactory receptor OR9-22;
GN   Name=OR1N1; Synonyms=OR1N3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1P1_HUMAN             Reviewed;         330 AA.
AC   Q8NH06;
DE   RecName: Full=Olfactory receptor 1P1;
DE   AltName: Full=Olfactory receptor 17-208;
DE            Short=OR17-208;
DE   AltName: Full=Olfactory receptor OR17-9;
GN   Name=OR1P1; Synonyms=OR1P1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1N2_HUMAN             Reviewed;         330 AA.
AC   Q8NGR9; A3KFM2; B2RNY4; Q6IF17; Q96RA3;
DE   RecName: Full=Olfactory receptor 1N2;
DE   AltName: Full=Olfactory receptor OR9-23;
GN   Name=OR1N2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1Q1_HUMAN             Reviewed;         314 AA.
AC   Q15612; Q6IFN4; Q8NGR7; Q96R82;
DE   RecName: Full=Olfactory receptor 1Q1;
DE   AltName: Full=OST226;
DE   AltName: Full=Olfactory receptor 1Q2;
DE   AltName: Full=Olfactory receptor 1Q3;
DE   AltName: Full=Olfactory receptor 9-A;
DE            Short=OR9-A;
DE   AltName: Full=Olfactory receptor OR9-25;
DE   AltName: Full=Olfactory receptor TPCR106;
GN   Name=OR1Q1; Synonyms=OR1Q2, OR1Q3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR1S1_HUMAN             Reviewed;         325 AA.
AC   Q8NH92; Q6IFG3;
DE   RecName: Full=Olfactory receptor 1S1;
DE   AltName: Full=Olfactory receptor OR11-232;
GN   Name=OR1S1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR1S2_HUMAN             Reviewed;         325 AA.
AC   Q8NGQ3; Q6IFG5; Q96R85;
DE   RecName: Full=Olfactory receptor 1S2;
DE   AltName: Full=Olfactory receptor OR11-231;
GN   Name=OR1S2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2A4_HUMAN             Reviewed;         310 AA.
AC   O95047; Q0VAR3; Q6IF18; Q9NQN0;
DE   RecName: Full=Olfactory receptor 2A4;
DE   AltName: Full=Olfactory receptor 2A10;
DE   AltName: Full=Olfactory receptor OR6-37;
GN   Name=OR2A4; Synonyms=OR2A10;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProt.
//
ID   OR2A7_HUMAN             Reviewed;         310 AA.
AC   Q96R45; B2RN57; Q6IFP4;
DE   RecName: Full=Olfactory receptor 2A7;
DE   AltName: Full=Olfactory receptor OR7-18;
GN   Name=OR2A7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2A5_HUMAN             Reviewed;         311 AA.
AC   Q96R48; B9EGX2; O43885; O43888;
DE   RecName: Full=Olfactory receptor 2A5;
DE   AltName: Full=Olfactory receptor 2A26;
DE   AltName: Full=Olfactory receptor 2A8;
DE   AltName: Full=Olfactory receptor 7-138/7-141;
DE            Short=OR7-138;
DE            Short=OR7-141;
GN   Name=OR2A5; Synonyms=OR2A26, OR2A8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2A2_HUMAN             Reviewed;         318 AA.
AC   Q6IF42; B2RN85; Q8NGT6;
DE   RecName: Full=Olfactory receptor 2A2;
DE   AltName: Full=Olfactory receptor 2A17;
DE   AltName: Full=Olfactory receptor OR7-11;
GN   Name=OR2A2; Synonyms=OR2A17P, OR2A2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2B2_HUMAN             Reviewed;         357 AA.
AC   Q9GZK3; B2RNH2; Q9GZL2; Q9Y299;
DE   RecName: Full=Olfactory receptor 2B2;
DE   AltName: Full=Hs6M1-10;
DE   AltName: Full=Olfactory receptor 2B9;
DE   AltName: Full=Olfactory receptor 6-1;
DE            Short=OR6-1;
GN   Name=OR2B2; Synonyms=OR2B9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2A1_HUMAN             Reviewed;         310 AA.
AC   Q8NGT9; Q6IF44; Q96R46;
DE   RecName: Full=Olfactory receptor 2A1/2A42;
DE   AltName: Full=Olfactory receptor OR7-16;
DE   AltName: Full=Olfactory receptor OR7-19;
GN   Name=OR2A1;
GN   and
GN   Name=OR2A42;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2B8_HUMAN             Reviewed;         312 AA.
AC   P59922;
DE   RecName: Full=Putative olfactory receptor 2B8;
DE   AltName: Full=Hs6M1-29P;
GN   Name=OR2B8P; Synonyms=OR2B8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2B6_HUMAN             Reviewed;         313 AA.
AC   P58173; O43883; Q6IF89; Q9H5B0;
DE   RecName: Full=Olfactory receptor 2B6;
DE   AltName: Full=Hs6M1-32;
DE   AltName: Full=Olfactory receptor 2B1;
DE   AltName: Full=Olfactory receptor 2B5;
DE   AltName: Full=Olfactory receptor 5-40;
DE            Short=OR5-40;
DE   AltName: Full=Olfactory receptor 6-31;
DE            Short=OR6-31;
DE   AltName: Full=Olfactory receptor OR6-4;
GN   Name=OR2B6; Synonyms=OR2B1, OR2B1P, OR2B5, OR2B6P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2B3_HUMAN             Reviewed;         313 AA.
AC   O76000; B0UYQ1; Q5ST41; Q96R13;
DE   RecName: Full=Putative olfactory receptor 2B3;
DE   AltName: Full=Hs6M1-1;
DE   AltName: Full=Olfactory receptor OR6-14;
DE            Short=OR6-4;
DE            Short=Olfactory receptor 6-4;
GN   Name=OR2B3; Synonyms=OR2B3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2C1_HUMAN             Reviewed;         312 AA.
AC   O95371; A0AVA4; Q6IF34; Q6IF55;
DE   RecName: Full=Olfactory receptor 2C1;
DE   AltName: Full=OLFmf3;
DE   AltName: Full=Olfactory receptor 2C2;
DE   AltName: Full=Olfactory receptor OR16-1;
DE   AltName: Full=Olfactory receptor OR16-2;
GN   Name=OR2C1; Synonyms=OR2C2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; TAS:ProtInc.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; TAS:GOC.
//
ID   OR2BB_HUMAN             Reviewed;         317 AA.
AC   Q5JQS5; B2RP03;
DE   RecName: Full=Olfactory receptor 2B11;
GN   Name=OR2B11;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2D2_HUMAN             Reviewed;         308 AA.
AC   Q9H210; B9EIL5; O95224; Q6IF28; Q8NGH4; Q96R52;
DE   RecName: Full=Olfactory receptor 2D2;
DE   AltName: Full=HB2;
DE   AltName: Full=Olfactory receptor 11-610;
DE            Short=OR11-610;
DE   AltName: Full=Olfactory receptor 2D1;
DE   AltName: Full=Olfactory receptor OR11-88;
GN   Name=OR2D2; Synonyms=OR2D1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR2F1_HUMAN             Reviewed;         317 AA.
AC   Q13607; A4D2G1; Q6IFP7; Q96R49; Q9UDX1;
DE   RecName: Full=Olfactory receptor 2F1;
DE   AltName: Full=Olfactory receptor 2F3;
DE   AltName: Full=Olfactory receptor 2F4;
DE   AltName: Full=Olfactory receptor 2F5;
DE   AltName: Full=Olfactory receptor-like protein OLF3;
GN   Name=OR2F1; Synonyms=OLF3, OR2F3, OR2F3P, OR2F4, OR2F5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   OR2F2_HUMAN             Reviewed;         317 AA.
AC   O95006; A4D2G0; Q6IFP8;
DE   RecName: Full=Olfactory receptor 2F2;
DE   AltName: Full=Olfactory receptor 7-1;
DE            Short=OR7-1;
DE   AltName: Full=Olfactory receptor OR7-6;
GN   Name=OR2F2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2G2_HUMAN             Reviewed;         317 AA.
AC   Q8NGZ5; Q5JQT2; Q6IEZ0;
DE   RecName: Full=Olfactory receptor 2G2;
DE   AltName: Full=Olfactory receptor OR1-32;
GN   Name=OR2G2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2D3_HUMAN             Reviewed;         330 AA.
AC   Q8NGH3; B2RP06; Q6IFG8; Q96R51;
DE   RecName: Full=Olfactory receptor 2D3;
DE   AltName: Full=Olfactory receptor OR11-89;
GN   Name=OR2D3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2G3_HUMAN             Reviewed;         309 AA.
AC   Q8NGZ4; B2RN64; Q5JQT1; Q6IF45;
DE   RecName: Full=Olfactory receptor 2G3;
DE   AltName: Full=Olfactory receptor OR1-33;
GN   Name=OR2G3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2G6_HUMAN             Reviewed;         316 AA.
AC   Q5TZ20; B2RP33;
DE   RecName: Full=Olfactory receptor 2G6;
GN   Name=OR2G6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2H1_HUMAN             Reviewed;         316 AA.
AC   Q9GZK4; B0S7T4; O43629; O43661; O43662; Q5SUN6; Q9GZK9;
DE   RecName: Full=Olfactory receptor 2H1;
DE   AltName: Full=Hs6M1-16;
DE   AltName: Full=OLFR42A-9004.14/9026.2;
DE   AltName: Full=Olfactory receptor 2H6;
DE   AltName: Full=Olfactory receptor 2H8;
DE   AltName: Full=Olfactory receptor 6-2;
DE            Short=OR6-2;
DE   AltName: Full=Olfactory receptor OR6-32;
GN   Name=OR2H1; Synonyms=OR2H6, OR2H8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2C3_HUMAN             Reviewed;         320 AA.
AC   Q8N628; Q5JQS4; Q6IEZ1; Q8NGW7;
DE   RecName: Full=Olfactory receptor 2C3;
DE   AltName: Full=Olfactory receptor 2C4;
DE   AltName: Full=Olfactory receptor 2C5;
DE   AltName: Full=Olfactory receptor OR1-30;
GN   Name=OR2C3; Synonyms=OR2C4, OR2C5P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2J1_HUMAN             Reviewed;         312 AA.
AC   Q9GZK6; A2AAS1; B0V1T2; Q9GZK1;
DE   RecName: Full=Olfactory receptor 2J1;
DE   AltName: Full=Hs6M1-4;
DE   AltName: Full=Olfactory receptor 6-5;
DE            Short=OR6-5;
GN   Name=OR2J1; Synonyms=OR2J1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2J2_HUMAN             Reviewed;         312 AA.
AC   O76002; A6NCU9; A6NLD0; B0UY53; Q32N09; Q5ST39; Q5SUJ6; Q6IF24;
AC   Q9GZK2; Q9GZL3;
DE   RecName: Full=Olfactory receptor 2J2;
DE   AltName: Full=Hs6M1-6;
DE   AltName: Full=Olfactory receptor 6-8;
DE            Short=OR6-8;
DE   AltName: Full=Olfactory receptor OR6-19;
GN   Name=OR2J2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2K2_HUMAN             Reviewed;         345 AA.
AC   Q8NGT1; Q2TA61; Q5VYK4; Q6IFI5;
DE   RecName: Full=Olfactory receptor 2K2;
DE   AltName: Full=HTPCRH06;
DE   AltName: Full=Olfactory receptor OR9-17;
GN   Name=OR2K2; Synonyms=OR2AR1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2I1_HUMAN             Reviewed;         316 AA.
AC   Q8NGU4;
DE   RecName: Full=Putative olfactory receptor 2I1;
DE   AltName: Full=Putative olfactory receptor 2I2;
DE   AltName: Full=Putative olfactory receptor 2I3;
DE   AltName: Full=Putative olfactory receptor 2I4;
GN   Name=OR2I1P; Synonyms=OR2I2, OR2I3P, OR2I4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2L2_HUMAN             Reviewed;         312 AA.
AC   Q8NH16; Q2M3T5;
DE   RecName: Full=Olfactory receptor 2L2;
DE   AltName: Full=HTPCRH07;
DE   AltName: Full=Olfactory receptor 2L12;
DE   AltName: Full=Olfactory receptor 2L4;
GN   Name=OR2L2; Synonyms=OR2L12, OR2L4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2J3_HUMAN             Reviewed;         311 AA.
AC   O76001; B0UY52; B9EH11; Q5SUJ7; Q6IF25; Q96R15; Q9GZK5; Q9GZL4;
AC   Q9GZL5;
DE   RecName: Full=Olfactory receptor 2J3;
DE   AltName: Full=Hs6M1-3;
DE   AltName: Full=Olfactory receptor OR6-16;
DE            Short=OR6-6;
DE            Short=Olfactory receptor 6-6;
GN   Name=OR2J3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2L3_HUMAN             Reviewed;         312 AA.
AC   Q8NG85; B9EH44;
DE   RecName: Full=Olfactory receptor 2L3;
GN   Name=OR2L3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2L8_HUMAN             Reviewed;         312 AA.
AC   Q8NGY9; Q6IF03;
DE   RecName: Full=Olfactory receptor 2L8;
DE   AltName: Full=Olfactory receptor OR1-46;
GN   Name=OR2L8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2LD_HUMAN             Reviewed;         312 AA.
AC   Q8N349; Q5VUR5;
DE   RecName: Full=Olfactory receptor 2L13;
DE   AltName: Full=Olfactory receptor 2L14;
GN   Name=OR2L13; Synonyms=OR2L14;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   OR2H2_HUMAN             Reviewed;         312 AA.
AC   O95918; Q15062; Q2M1Y3; Q5STL8; Q5SUK1; Q6IFN7; Q6NTB7; Q96R14;
DE   RecName: Full=Olfactory receptor 2H2;
DE   AltName: Full=Hs6M1-12;
DE   AltName: Full=Olfactory receptor 2H3;
DE   AltName: Full=Olfactory receptor-like protein FAT11;
GN   Name=OR2H2; Synonyms=FAT11, OLFR2, OR2H3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; TAS:GOC.
DR   GO; GO:0007618; P:mating; TAS:ProtInc.
//
ID   OR2L5_HUMAN             Reviewed;         312 AA.
AC   Q8NG80; Q6IF04;
DE   RecName: Full=Olfactory receptor 2L5;
DE   AltName: Full=Olfactory receptor 2L11;
DE   AltName: Full=Olfactory receptor OR1-53;
GN   Name=OR2L5; Synonyms=OR2L11;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2M3_HUMAN             Reviewed;         312 AA.
AC   Q8NG83; B9EH06; Q6IEY0;
DE   RecName: Full=Olfactory receptor 2M3;
DE   AltName: Full=Olfactory receptor 2M6;
DE   AltName: Full=Olfactory receptor OR1-54;
GN   Name=OR2M3; Synonyms=OR2M3P, OR2M6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2M5_HUMAN             Reviewed;         312 AA.
AC   A3KFT3;
DE   RecName: Full=Olfactory receptor 2M5;
GN   Name=OR2M5; Synonyms=OR2M5P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2M4_HUMAN             Reviewed;         311 AA.
AC   Q96R27; Q15611; Q8NG82;
DE   RecName: Full=Olfactory receptor 2M4;
DE   AltName: Full=HTPCRX18;
DE   AltName: Full=OST710;
DE   AltName: Full=Olfactory receptor OR1-55;
DE   AltName: Full=Olfactory receptor TPCR100;
GN   Name=OR2M4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR2S1_HUMAN             Reviewed;         319 AA.
AC   Q9NQN1; Q2M3L0; Q6IF19; Q96R42;
DE   RecName: Full=Olfactory receptor 2S2;
DE   AltName: Full=Olfactory receptor OR9-3;
GN   Name=OR2S2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR2M2_HUMAN             Reviewed;         347 AA.
AC   Q96R28; A3KFT4;
DE   RecName: Full=Olfactory receptor 2M2;
DE   AltName: Full=OST423;
GN   Name=OR2M2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T1_HUMAN             Reviewed;         369 AA.
AC   O43869; Q6IEZ9;
DE   RecName: Full=Olfactory receptor 2T1;
DE   AltName: Full=Olfactory receptor 1-25;
DE            Short=OR1-25;
DE   AltName: Full=Olfactory receptor OR1-61;
GN   Name=OR2T1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T2_HUMAN             Reviewed;         324 AA.
AC   Q6IF00; B2RNM1; B9EH01;
DE   RecName: Full=Olfactory receptor 2T2;
DE   AltName: Full=Olfactory receptor OR1-43;
GN   Name=OR2T2; Synonyms=OR2T2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2M7_HUMAN             Reviewed;         312 AA.
AC   Q8NG81; B2RNL0; Q6IEX6;
DE   RecName: Full=Olfactory receptor 2M7;
DE   AltName: Full=Olfactory receptor OR1-58;
GN   Name=OR2M7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T3_HUMAN             Reviewed;         318 AA.
AC   Q8NH03; B2RNJ1;
DE   RecName: Full=Olfactory receptor 2T3;
GN   Name=OR2T3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T4_HUMAN             Reviewed;         348 AA.
AC   Q8NH00; Q6IEZ8;
DE   RecName: Full=Olfactory receptor 2T4;
DE   AltName: Full=Olfactory receptor OR1-60;
GN   Name=OR2T4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T5_HUMAN             Reviewed;         315 AA.
AC   Q6IEZ7;
DE   RecName: Full=Olfactory receptor 2T5;
DE   AltName: Full=Olfactory receptor OR1-62;
GN   Name=OR2T5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T7_HUMAN             Reviewed;         308 AA.
AC   P0C7T2;
DE   RecName: Full=Olfactory receptor 2T7;
DE   AltName: Full=OST723;
DE   AltName: Full=olfactory receptor OR1-44;
GN   Name=OR2T7; Synonyms=OR2T7P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T8_HUMAN             Reviewed;         312 AA.
AC   A6NH00;
DE   RecName: Full=Olfactory receptor 2T8;
GN   Name=OR2T8; Synonyms=OR2T8P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2T6_HUMAN             Reviewed;         308 AA.
AC   Q8NHC8; A6NE36;
DE   RecName: Full=Olfactory receptor 2T6;
DE   AltName: Full=OST703;
DE   AltName: Full=Olfactory receptor 2T9;
GN   Name=OR2T6; Synonyms=OR2T6P, OR2T9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2V1_HUMAN             Reviewed;         315 AA.
AC   Q8NHB1;
DE   RecName: Full=Olfactory receptor 2V1;
GN   Name=OR2V1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2V2_HUMAN             Reviewed;         315 AA.
AC   Q96R30; Q6IFL6; Q8NGV1;
DE   RecName: Full=Olfactory receptor 2V2;
DE   AltName: Full=Olfactory receptor 2V3;
DE   AltName: Full=Olfactory receptor OR5-3;
GN   Name=OR2V2; Synonyms=OR2V3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2W1_HUMAN             Reviewed;         320 AA.
AC   Q9Y3N9; B0S7Y5; Q5JNZ1; Q6IEU0; Q96R17; Q9GZL0; Q9GZL1;
DE   RecName: Full=Olfactory receptor 2W1;
DE   AltName: Full=Hs6M1-15;
DE   AltName: Full=Olfactory receptor OR6-13;
GN   Name=OR2W1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2W5_HUMAN             Reviewed;         320 AA.
AC   A6NFC9; B9EH85;
DE   RecName: Full=Putative olfactory receptor 2W5;
GN   Name=OR2W5; Synonyms=OR2W5P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2W6_HUMAN             Reviewed;         318 AA.
AC   Q8NHA6;
DE   RecName: Full=Putative olfactory receptor 2W6;
DE   AltName: Full=Olfactory receptor OR6-3;
DE   AltName: Full=Putative olfactory receptor 2W7;
GN   Name=OR2W6P; Synonyms=OR2W7P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2W3_HUMAN             Reviewed;         314 AA.
AC   Q7Z3T1; Q6IF06; Q8NG86;
DE   RecName: Full=Olfactory receptor 2W3;
DE   AltName: Full=Olfactory receptor 2W8;
DE   AltName: Full=Olfactory receptor OR1-49;
GN   Name=OR2W3; Synonyms=OR2W3P, OR2W8P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2Y1_HUMAN             Reviewed;         311 AA.
AC   Q8NGV0; B9EIP1; Q6IFB1; Q96R16;
DE   RecName: Full=Olfactory receptor 2Y1;
DE   AltName: Full=Olfactory receptor OR5-2;
GN   Name=OR2Y1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR2Z1_HUMAN             Reviewed;         314 AA.
AC   Q8NG97; B9EH50; Q6IFK0; Q96R25;
DE   RecName: Full=Olfactory receptor 2Z1;
DE   AltName: Full=Olfactory receptor 2Z2;
DE   AltName: Full=Olfactory receptor OR19-4;
GN   Name=OR2Z1; Synonyms=OR2Z2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR3A1_HUMAN             Reviewed;         315 AA.
AC   P47881; Q4VB06; Q6IFM4;
DE   RecName: Full=Olfactory receptor 3A1;
DE   AltName: Full=Olfactory receptor 17-40;
DE            Short=OR17-40;
DE   AltName: Full=Olfactory receptor OR17-15;
GN   Name=OR3A1; Synonyms=OLFRA03;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; TAS:ProtInc.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   OR3A2_HUMAN             Reviewed;         321 AA.
AC   P47893; Q6IFM3; Q9P1Q3;
DE   RecName: Full=Olfactory receptor 3A2;
DE   AltName: Full=Olfactory receptor 17-228;
DE            Short=OR17-228;
DE   AltName: Full=Olfactory receptor OR17-14;
GN   Name=OR3A2; Synonyms=OLFRA04;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   OR3A3_HUMAN             Reviewed;         321 AA.
AC   P47888; Q2VPE4; Q6IFM6; Q9P1Q4; Q9UBE7;
DE   RecName: Full=Olfactory receptor 3A3;
DE   AltName: Full=Olfactory receptor 17-201;
DE            Short=OR17-201;
DE   AltName: Full=Olfactory receptor 3A6;
DE   AltName: Full=Olfactory receptor 3A7;
DE   AltName: Full=Olfactory receptor 3A8;
DE   AltName: Full=Olfactory receptor OR17-22;
GN   Name=OR3A3; Synonyms=OR3A6, OR3A7, OR3A8P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   OR3A4_HUMAN             Reviewed;         348 AA.
AC   P47883; Q96R24;
DE   RecName: Full=Putative olfactory receptor 3A4;
DE   AltName: Full=Olfactory receptor 17-24;
DE            Short=OR17-24;
DE   AltName: Full=Olfactory receptor 3A5;
GN   Name=OR3A4P; Synonyms=OR3A4, OR3A5P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR4A4_HUMAN             Reviewed;         299 AA.
AC   Q8NGN8; Q6IF83; Q96R66;
DE   RecName: Full=Putative olfactory receptor 4A4;
DE   AltName: Full=Olfactory receptor OR11-107;
GN   Name=OR4A4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4A5_HUMAN             Reviewed;         315 AA.
AC   Q8NH83; Q6IF84;
DE   RecName: Full=Olfactory receptor 4A5;
DE   AltName: Full=Olfactory receptor OR11-111;
GN   Name=OR4A5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4A8_HUMAN             Reviewed;         315 AA.
AC   P0C604;
DE   RecName: Full=Putative olfactory receptor 4A8;
DE   AltName: Full=Olfactory receptor OR11-110;
GN   Name=OR4A8P; Synonyms=OR4A8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4B1_HUMAN             Reviewed;         309 AA.
AC   Q8NGF8; Q6IF75; Q96R64;
DE   RecName: Full=Olfactory receptor 4B1;
DE   AltName: Full=OST208;
DE   AltName: Full=Olfactory receptor OR11-106;
GN   Name=OR4B1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4C3_HUMAN             Reviewed;         302 AA.
AC   Q8NH37; B2RNF2; Q6IFB3;
DE   RecName: Full=Olfactory receptor 4C3;
DE   AltName: Full=Olfactory receptor OR11-98;
GN   Name=OR4C3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4C5_HUMAN             Reviewed;         326 AA.
AC   Q8NGB2; Q6IFB2;
DE   RecName: Full=Olfactory receptor 4C5;
DE   AltName: Full=Olfactory receptor OR11-99;
GN   Name=OR4C5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4C6_HUMAN             Reviewed;         309 AA.
AC   Q8NH72; B2RP11; Q6IFD2;
DE   RecName: Full=Olfactory receptor 4C6;
DE   AltName: Full=Olfactory receptor OR11-138;
GN   Name=OR4C6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4CB_HUMAN             Reviewed;         310 AA.
AC   Q6IEV9; B9EIL4; Q8NGL8;
DE   RecName: Full=Olfactory receptor 4C11;
DE   AltName: Full=Olfactory receptor OR11-136;
GN   Name=OR4C11; Synonyms=OR4C11P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4CC_HUMAN             Reviewed;         309 AA.
AC   Q96R67; B2RNF0; Q6IF49;
DE   RecName: Full=Olfactory receptor 4C12;
DE   AltName: Full=Olfactory receptor OR11-259;
GN   Name=OR4C12;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4CD_HUMAN             Reviewed;         309 AA.
AC   Q8NGP0; A6NJJ3; B9EH30; Q6IF48; Q96R68;
DE   RecName: Full=Olfactory receptor 4C13;
DE   AltName: Full=Olfactory receptor OR11-260;
GN   Name=OR4C13;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4CF_HUMAN             Reviewed;         316 AA.
AC   Q8NGM1; Q6IFE2;
DE   RecName: Full=Olfactory receptor 4C15;
DE   AltName: Full=Olfactory receptor OR11-127;
DE   AltName: Full=Olfactory receptor OR11-134;
GN   Name=OR4C15;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4D1_HUMAN             Reviewed;         310 AA.
AC   Q15615; B2RN14; Q8NGB1; Q96R76;
DE   RecName: Full=Olfactory receptor 4D1;
DE   AltName: Full=Olfactory receptor 4D3;
DE   AltName: Full=Olfactory receptor TPCR16;
GN   Name=OR4D1; Synonyms=OR4D3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR4D2_HUMAN             Reviewed;         307 AA.
AC   P58180; Q6IFN8; Q96R75;
DE   RecName: Full=Olfactory receptor 4D2;
DE   AltName: Full=B-lymphocyte membrane protein BC2009;
DE   AltName: Full=Olfactory receptor OR17-24;
GN   Name=OR4D2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4CG_HUMAN             Reviewed;         310 AA.
AC   Q8NGL9; Q6IEV8;
DE   RecName: Full=Olfactory receptor 4C16;
DE   AltName: Full=Olfactory receptor OR11-135;
GN   Name=OR4C16;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4D5_HUMAN             Reviewed;         318 AA.
AC   Q8NGN0; B9EGZ4; Q6IFE6;
DE   RecName: Full=Olfactory receptor 4D5;
DE   AltName: Full=Olfactory receptor OR11-276;
GN   Name=OR4D5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4D9_HUMAN             Reviewed;         314 AA.
AC   Q8NGE8; Q6IFF3;
DE   RecName: Full=Olfactory receptor 4D9;
DE   AltName: Full=Olfactory receptor OR11-253;
GN   Name=OR4D9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4D6_HUMAN             Reviewed;         314 AA.
AC   Q8NGJ1; B2RNP7; Q6IFF5; Q96R74;
DE   RecName: Full=Olfactory receptor 4D6;
DE   AltName: Full=Olfactory receptor OR11-250;
GN   Name=OR4D6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4DA_HUMAN             Reviewed;         311 AA.
AC   Q8NGI6; B2RNH6;
DE   RecName: Full=Olfactory receptor 4D10;
DE   AltName: Full=Olfactory receptor OR11-251;
GN   Name=OR4D10; Synonyms=OR4D10P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4DB_HUMAN             Reviewed;         311 AA.
AC   Q8NGI4;
DE   RecName: Full=Olfactory receptor 4D11;
GN   Name=OR4D11; Synonyms=OR4D11P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4E1_HUMAN             Reviewed;         316 AA.
AC   P0C645;
DE   RecName: Full=Olfactory receptor 4E1;
DE   AltName: Full=Olfactory receptor OR14-43;
GN   Name=OR4E1; Synonyms=OR4E1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4F3_HUMAN             Reviewed;         312 AA.
AC   Q6IEY1; B2RPQ6;
DE   RecName: Full=Olfactory receptor 4F3/4F16/4F29;
DE   AltName: Full=Olfactory receptor OR1-1;
GN   Name=OR4F3;
GN   and
GN   Name=OR4F16;
GN   and
GN   Name=OR4F29;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4E2_HUMAN             Reviewed;         313 AA.
AC   Q8NGC2; Q6IET6; Q96R62;
DE   RecName: Full=Olfactory receptor 4E2;
DE   AltName: Full=Olfactory receptor OR14-42;
GN   Name=OR4E2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4F4_HUMAN             Reviewed;         305 AA.
AC   Q96R69; B2RNI5; Q6IFN9;
DE   RecName: Full=Olfactory receptor 4F4;
DE   AltName: Full=HS14a-1-A;
DE   AltName: Full=Olfactory receptor OR19-3;
GN   Name=OR4F4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4F6_HUMAN             Reviewed;         312 AA.
AC   Q8NGB9; B9EH28; Q6IF95;
DE   RecName: Full=Olfactory receptor 4F6;
DE   AltName: Full=Olfactory receptor 4F12;
DE   AltName: Full=Olfactory receptor OR15-15;
GN   Name=OR4F6; Synonyms=OR4F12;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4F5_HUMAN             Reviewed;         305 AA.
AC   Q8NH21; Q5VT22;
DE   RecName: Full=Olfactory receptor 4F5;
GN   Name=OR4F5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4K1_HUMAN             Reviewed;         311 AA.
AC   Q8NGD4; B9EKV9; Q8NGD6; Q96R73;
DE   RecName: Full=Olfactory receptor 4K1;
DE   AltName: Full=Olfactory receptor OR14-19;
GN   Name=OR4K1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4FL_HUMAN             Reviewed;         273 AA.
AC   Q32VQ0;
DE   RecName: Full=Putative olfactory receptor GPCRLTM7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4K2_HUMAN             Reviewed;         314 AA.
AC   Q8NGD2; B2RNK8; Q6IFA5;
DE   RecName: Full=Olfactory receptor 4K2;
DE   AltName: Full=Olfactory receptor OR14-15;
GN   Name=OR4K2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4K3_HUMAN             Reviewed;         315 AA.
AC   Q96R72; Q6IFA4;
DE   RecName: Full=Olfactory receptor 4K3;
DE   AltName: Full=Olfactory receptor OR14-14;
GN   Name=OR4K3; Synonyms=OR4K3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4K5_HUMAN             Reviewed;         323 AA.
AC   Q8NGD3; Q6IFA7;
DE   RecName: Full=Olfactory receptor 4K5;
DE   AltName: Full=Olfactory receptor OR14-16;
GN   Name=OR4K5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4KD_HUMAN             Reviewed;         304 AA.
AC   Q8NH42; Q6IF13;
DE   RecName: Full=Olfactory receptor 4K13;
DE   AltName: Full=Olfactory receptor OR14-27;
GN   Name=OR4K13;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4KE_HUMAN             Reviewed;         310 AA.
AC   Q8NGD5; Q6IEU1; Q96R71;
DE   RecName: Full=Olfactory receptor 4K14;
DE   AltName: Full=Olfactory receptor OR14-22;
GN   Name=OR4K14;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4KF_HUMAN             Reviewed;         348 AA.
AC   Q8NH41; B9EIL3; Q6IEZ4;
DE   RecName: Full=Olfactory receptor 4K15;
DE   AltName: Full=Olfactory receptor OR14-20;
GN   Name=OR4K15;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4KH_HUMAN             Reviewed;         315 AA.
AC   Q8NGC6; Q6IF12;
DE   RecName: Full=Olfactory receptor 4K17;
DE   AltName: Full=Olfactory receptor OR14-29;
GN   Name=OR4K17;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4L1_HUMAN             Reviewed;         312 AA.
AC   Q8NH43; Q6IEZ5;
DE   RecName: Full=Olfactory receptor 4L1;
DE   AltName: Full=Olfactory receptor 4L2;
DE   AltName: Full=Olfactory receptor OR14-28;
GN   Name=OR4L1; Synonyms=OR4L2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4M1_HUMAN             Reviewed;         313 AA.
AC   Q8NGD0; B9EH18; Q6IFA3;
DE   RecName: Full=Olfactory receptor 4M1;
DE   AltName: Full=Olfactory receptor OR14-7;
GN   Name=OR4M1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4M2_HUMAN             Reviewed;         313 AA.
AC   Q8NGB6; B9EH16; Q6IEY2;
DE   RecName: Full=Olfactory receptor 4M2;
DE   AltName: Full=Olfactory receptor OR15-3;
GN   Name=OR4M2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4N2_HUMAN             Reviewed;         307 AA.
AC   Q8NGD1; Q6IEY9; Q6IFA2;
DE   RecName: Full=Olfactory receptor 4N2;
DE   AltName: Full=Olfactory receptor OR14-13;
DE   AltName: Full=Olfactory receptor OR14-8;
GN   Name=OR4N2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4N4_HUMAN             Reviewed;         316 AA.
AC   Q8N0Y3; Q6IEY3; Q6IF56;
DE   RecName: Full=Olfactory receptor 4N4;
DE   AltName: Full=Olfactory receptor OR15-1;
DE   AltName: Full=Olfactory receptor OR15-5;
GN   Name=OR4N4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4N5_HUMAN             Reviewed;         308 AA.
AC   Q8IXE1; Q6IF11;
DE   RecName: Full=Olfactory receptor 4N5;
DE   AltName: Full=Olfactory receptor OR14-33;
GN   Name=OR4N5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4P4_HUMAN             Reviewed;         312 AA.
AC   Q8NGL7;
DE   RecName: Full=Olfactory receptor 4P4;
DE   AltName: Full=Olfactory receptor 4P3;
GN   Name=OR4P4; Synonyms=OR4P3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4Q3_HUMAN             Reviewed;         313 AA.
AC   Q8NH05; Q6IEX4;
DE   RecName: Full=Olfactory receptor 4Q3;
DE   AltName: Full=Olfactory receptor 4Q4;
DE   AltName: Full=Olfactory receptor OR14-3;
GN   Name=OR4Q3; Synonyms=C14orf13, OR4Q4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4S1_HUMAN             Reviewed;         309 AA.
AC   Q8NGB4; Q6IFB4;
DE   RecName: Full=Olfactory receptor 4S1;
DE   AltName: Full=Olfactory receptor OR11-100;
GN   Name=OR4S1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4S2_HUMAN             Reviewed;         311 AA.
AC   Q8NH73; Q6IF72;
DE   RecName: Full=Olfactory receptor 4S2;
DE   AltName: Full=Olfactory receptor OR11-137;
GN   Name=OR4S2; Synonyms=OR4S2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4Q2_HUMAN             Reviewed;         313 AA.
AC   P0C623;
DE   RecName: Full=Olfactory receptor 4Q2;
DE   AltName: Full=olfactory receptor OR14-21;
GN   Name=OR4Q2; Synonyms=OR4Q2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4X1_HUMAN             Reviewed;         305 AA.
AC   Q8NH49; Q6IF74;
DE   RecName: Full=Olfactory receptor 4X1;
DE   AltName: Full=Olfactory receptor OR11-104;
GN   Name=OR4X1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR4X2_HUMAN             Reviewed;         303 AA.
AC   Q8NGF9; B2RNK3; Q6IF73; Q96R63;
DE   RecName: Full=Olfactory receptor 4X2;
DE   AltName: Full=Olfactory receptor OR11-105;
GN   Name=OR4X2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5A1_HUMAN             Reviewed;         315 AA.
AC   Q8NGJ0; B9EH58; Q6IFF2; Q96RB1;
DE   RecName: Full=Olfactory receptor 5A1;
DE   AltName: Full=OST181;
DE   AltName: Full=Olfactory receptor OR11-249;
GN   Name=OR5A1; Synonyms=OR5A1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5A2_HUMAN             Reviewed;         324 AA.
AC   Q8NGI9; B9EH21; Q6IFF4; Q96RB0;
DE   RecName: Full=Olfactory receptor 5A2;
DE   AltName: Full=Olfactory receptor OR11-248;
GN   Name=OR5A2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5B3_HUMAN             Reviewed;         314 AA.
AC   Q8NH48; Q6IEV6;
DE   RecName: Full=Olfactory receptor 5B3;
DE   AltName: Full=Olfactory receptor 5B13;
DE   AltName: Full=Olfactory receptor OR11-239;
GN   Name=OR5B3; Synonyms=OR5B13;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5B2_HUMAN             Reviewed;         309 AA.
AC   Q96R09; B2RNJ6; B9EGY7; Q6IEV7; Q8NGF5;
DE   RecName: Full=Olfactory receptor 5B2;
DE   AltName: Full=OST073;
DE   AltName: Full=Olfactory receptor OR11-240;
GN   Name=OR5B2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5BC_HUMAN             Reviewed;         314 AA.
AC   Q96R08; B2RNL2; Q6IEV5;
DE   RecName: Full=Olfactory receptor 5B12;
DE   AltName: Full=Olfactory receptor 5B16;
DE   AltName: Full=Olfactory receptor OR11-241;
GN   Name=OR5B12; Synonyms=OR5B12P, OR5B16;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5C1_HUMAN             Reviewed;         320 AA.
AC   Q8NGR4; B2RN54; B9EGT0; Q96RC4;
DE   RecName: Full=Olfactory receptor 5C1;
DE   AltName: Full=Olfactory receptor 5C2;
DE   AltName: Full=Olfactory receptor 9-F;
DE            Short=OR9-F;
GN   Name=OR5C1; Synonyms=OR5C2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5BL_HUMAN             Reviewed;         309 AA.
AC   A6NL26;
DE   RecName: Full=Olfactory receptor 5B21;
GN   Name=OR5B21;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5BH_HUMAN             Reviewed;         314 AA.
AC   Q8NGF7; Q6IEX1;
DE   RecName: Full=Olfactory receptor 5B17;
DE   AltName: Full=Olfactory receptor 5B20;
DE   AltName: Full=Olfactory receptor OR11-237;
GN   Name=OR5B17; Synonyms=OR5B20P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5DD_HUMAN             Reviewed;         314 AA.
AC   Q8NGL4; Q6IF68; Q6IFC9;
DE   RecName: Full=Olfactory receptor 5D13;
DE   AltName: Full=Olfactory receptor OR11-142;
DE   AltName: Full=Olfactory receptor OR11-148;
GN   Name=OR5D13;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5DI_HUMAN             Reviewed;         313 AA.
AC   Q8NGL1; Q6IF67; Q6IFD3; Q96RB3;
DE   RecName: Full=Olfactory receptor 5D18;
DE   AltName: Full=Olfactory receptor OR11-143;
DE   AltName: Full=Olfactory receptor OR11-152;
GN   Name=OR5D18;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5DE_HUMAN             Reviewed;         314 AA.
AC   Q8NGL3; Q6IF69; Q6IFD4; Q96RB5;
DE   RecName: Full=Olfactory receptor 5D14;
DE   AltName: Full=Olfactory receptor OR11-141;
DE   AltName: Full=Olfactory receptor OR11-150;
GN   Name=OR5D14;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5F1_HUMAN             Reviewed;         314 AA.
AC   O95221; Q495D1; Q6IFB9;
DE   RecName: Full=Olfactory receptor 5F1;
DE   AltName: Full=Olfactory receptor 11-10;
DE            Short=OR11-10;
DE   AltName: Full=Olfactory receptor OR11-167;
GN   Name=OR5F1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR5DG_HUMAN             Reviewed;         328 AA.
AC   Q8NGK9; Q6IF65; Q96RB4;
DE   RecName: Full=Olfactory receptor 5D16;
DE   AltName: Full=Olfactory receptor OR11-154;
GN   Name=OR5D16;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5H1_HUMAN             Reviewed;         313 AA.
AC   A6NKK0;
DE   RecName: Full=Olfactory receptor 5H1;
DE   AltName: Full=HTPCRX14;
GN   Name=OR5H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5G3_HUMAN             Reviewed;         314 AA.
AC   P0C626;
DE   RecName: Full=Olfactory receptor 5G3;
DE   AltName: Full=Olfactory receptor 5G6;
DE   AltName: Full=Olfactory receptor OR11-213;
GN   Name=OR5G3; Synonyms=OR5G3P, OR5G6P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5H2_HUMAN             Reviewed;         314 AA.
AC   Q8NGV7; Q6IF87;
DE   RecName: Full=Olfactory receptor 5H2;
DE   AltName: Full=Olfactory receptor OR3-10;
GN   Name=OR5H2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5H6_HUMAN             Reviewed;         325 AA.
AC   Q8NGV6; Q6IF88;
DE   RecName: Full=Olfactory receptor 5H6;
DE   AltName: Full=Olfactory receptor OR3-11;
GN   Name=OR5H6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5I1_HUMAN             Reviewed;         314 AA.
AC   Q13606; Q6IEU4;
DE   RecName: Full=Olfactory receptor 5I1;
DE   AltName: Full=Olfactory receptor OR11-159;
DE   AltName: Full=Olfactory receptor-like protein OLF1;
GN   Name=OR5I1; Synonyms=OLF1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   OR5J2_HUMAN             Reviewed;         312 AA.
AC   Q8NH18; Q6IEU5;
DE   RecName: Full=Olfactory receptor 5J2;
DE   AltName: Full=Olfactory receptor OR11-266;
GN   Name=OR5J2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5K2_HUMAN             Reviewed;         316 AA.
AC   Q8NHB8; B2RN70; Q6IF47;
DE   RecName: Full=Olfactory receptor 5K2;
DE   AltName: Full=Olfactory receptor OR3-9;
GN   Name=OR5K2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5K3_HUMAN             Reviewed;         321 AA.
AC   A6NET4;
DE   RecName: Full=Olfactory receptor 5K3;
GN   Name=OR5K3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5K1_HUMAN             Reviewed;         308 AA.
AC   Q8NHB7; B9EGY5; Q6IF46;
DE   RecName: Full=Olfactory receptor 5K1;
DE   AltName: Full=HTPCRX10;
DE   AltName: Full=Olfactory receptor OR3-8;
GN   Name=OR5K1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5L1_HUMAN             Reviewed;         311 AA.
AC   Q8NGL2; B2RNK6; Q6IFD0;
DE   RecName: Full=Olfactory receptor 5L1;
DE   AltName: Full=OST262;
DE   AltName: Full=Olfactory receptor OR11-151;
GN   Name=OR5L1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5M1_HUMAN             Reviewed;         315 AA.
AC   Q8NGP8; Q6IF60; Q96RB6;
DE   RecName: Full=Olfactory receptor 5M1;
DE   AltName: Full=OST050;
DE   AltName: Full=Olfactory receptor OR11-208;
GN   Name=OR5M1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5K4_HUMAN             Reviewed;         321 AA.
AC   A6NMS3;
DE   RecName: Full=Olfactory receptor 5K4;
GN   Name=OR5K4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5M3_HUMAN             Reviewed;         307 AA.
AC   Q8NGP4; B2RNM7; Q6IEW4; Q96RC0;
DE   RecName: Full=Olfactory receptor 5M3;
DE   AltName: Full=Olfactory receptor OR11-191;
GN   Name=OR5M3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5L2_HUMAN             Reviewed;         311 AA.
AC   Q8NGL0; Q6IF66; Q96RB2;
DE   RecName: Full=Olfactory receptor 5L2;
DE   AltName: Full=HTPCRX16;
DE   AltName: Full=Olfactory receptor OR11-153;
GN   Name=OR5L2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5M8_HUMAN             Reviewed;         311 AA.
AC   Q8NGP6; B2RNM5; Q6IEW3; Q96RB8;
DE   RecName: Full=Olfactory receptor 5M8;
DE   AltName: Full=Olfactory receptor OR11-194;
GN   Name=OR5M8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5M9_HUMAN             Reviewed;         310 AA.
AC   Q8NGP3; Q6IEW5; Q96RB9;
DE   RecName: Full=Olfactory receptor 5M9;
DE   AltName: Full=Olfactory receptor OR11-190;
GN   Name=OR5M9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5MB_HUMAN             Reviewed;         305 AA.
AC   Q96RB7; B2RNL5; B2RNL7;
DE   RecName: Full=Olfactory receptor 5M11;
GN   Name=OR5M11;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5MA_HUMAN             Reviewed;         315 AA.
AC   Q6IEU7; B9EIL9;
DE   RecName: Full=Olfactory receptor 5M10;
DE   AltName: Full=Olfactory receptor OR11-207;
GN   Name=OR5M10;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5P3_HUMAN             Reviewed;         311 AA.
AC   Q8WZ94; Q6IFE1; Q8NGM2;
DE   RecName: Full=Olfactory receptor 5P3;
DE   AltName: Full=Olfactory receptor OR11-94;
DE   AltName: Full=Olfactory receptor-like protein JCG1;
GN   Name=OR5P3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5P2_HUMAN             Reviewed;         322 AA.
AC   Q8WZ92; Q3MIS8;
DE   RecName: Full=Olfactory receptor 5P2;
DE   AltName: Full=Olfactory receptor-like protein JCG3;
GN   Name=OR5P2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5R1_HUMAN             Reviewed;         324 AA.
AC   Q8NH85;
DE   RecName: Full=Olfactory receptor 5R1;
DE   AltName: Full=Olfactory receptor OR11-185;
GN   Name=OR5R1; Synonyms=OR5R1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5T1_HUMAN             Reviewed;         326 AA.
AC   Q8NG75; B2RNM9;
DE   RecName: Full=Olfactory receptor 5T1;
DE   AltName: Full=Olfactory receptor OR11-179;
GN   Name=OR5T1; Synonyms=OR5T1P;
DR   GO; GO:0004935; F:adrenergic receptor activity; IEA:InterPro.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5T2_HUMAN             Reviewed;         359 AA.
AC   Q8NGG2; B9EGX5; Q6IFC8;
DE   RecName: Full=Olfactory receptor 5T2;
DE   AltName: Full=Olfactory receptor OR11-177;
GN   Name=OR5T2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5T3_HUMAN             Reviewed;         340 AA.
AC   Q8NGG3; Q6IFC7;
DE   RecName: Full=Olfactory receptor 5T3;
DE   AltName: Full=Olfactory receptor OR11-178;
GN   Name=OR5T3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5W2_HUMAN             Reviewed;         310 AA.
AC   Q8NH69;
DE   RecName: Full=Olfactory receptor 5W2;
DE   AltName: Full=Olfactory receptor 5W3;
DE   AltName: Full=Olfactory receptor OR11-155;
GN   Name=OR5W2; Synonyms=OR5W2P, OR5W3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR5V1_HUMAN             Reviewed;         321 AA.
AC   Q9UGF6; A2BDZ0; B0S860; Q5SQI9; Q6NTB5; Q8IVL3;
DE   RecName: Full=Olfactory receptor 5V1;
DE   AltName: Full=Hs6M1-21;
DE   AltName: Full=Olfactory receptor OR6-26;
GN   Name=OR5V1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6A2_HUMAN             Reviewed;         327 AA.
AC   O95222; Q3MJC7; Q6IF35; Q9H206;
DE   RecName: Full=Olfactory receptor 6A2;
DE   AltName: Full=Olfactory receptor 11-55;
DE            Short=OR11-55;
DE   AltName: Full=Olfactory receptor 6A1;
DE   AltName: Full=Olfactory receptor OR11-83;
DE   AltName: Full=hP2 olfactory receptor;
GN   Name=OR6A2; Synonyms=OR6A1, OR6A2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   OR6B1_HUMAN             Reviewed;         311 AA.
AC   O95007; A4D2G2; B9EH47; Q6IFP6; Q96R38;
DE   RecName: Full=Olfactory receptor 6B1;
DE   AltName: Full=Olfactory receptor 7-3;
DE            Short=OR7-3;
DE   AltName: Full=Olfactory receptor OR7-9;
GN   Name=OR6B1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6B2_HUMAN             Reviewed;         312 AA.
AC   Q6IFH4; B2RPR3; Q8NGW0;
DE   RecName: Full=Olfactory receptor 6B2;
DE   AltName: Full=Olfactory receptor OR2-1;
GN   Name=OR6B2; Synonyms=OR6B2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6B3_HUMAN             Reviewed;         331 AA.
AC   Q8NGW1; Q6IFH3;
DE   RecName: Full=Olfactory receptor 6B3;
DE   AltName: Full=Olfactory receptor OR2-2;
GN   Name=OR6B3; Synonyms=OR6B3P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6C1_HUMAN             Reviewed;         312 AA.
AC   Q96RD1; B2RNM0;
DE   RecName: Full=Olfactory receptor 6C1;
DE   AltName: Full=OST267;
GN   Name=OR6C1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6C2_HUMAN             Reviewed;         312 AA.
AC   Q9NZP2;
DE   RecName: Full=Olfactory receptor 6C2;
DE   AltName: Full=HSA3;
GN   Name=OR6C2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR6C4_HUMAN             Reviewed;         309 AA.
AC   Q8NGE1; A8MZG7; B2RNN2; Q6IFK1;
DE   RecName: Full=Olfactory receptor 6C4;
DE   AltName: Full=Olfactory receptor OR12-10;
GN   Name=OR6C4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6F1_HUMAN             Reviewed;         308 AA.
AC   Q8NGZ6; B2RNV6; Q6IF02; Q96R39;
DE   RecName: Full=Olfactory receptor 6F1;
DE   AltName: Full=Olfactory receptor OR1-38;
GN   Name=OR6F1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6J1_HUMAN             Reviewed;         347 AA.
AC   Q8NGC5;
DE   RecName: Full=Olfactory receptor 6J1;
DE   AltName: Full=Olfactory receptor 6J2;
GN   Name=OR6J1; Synonyms=OR6J2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6C6_HUMAN             Reviewed;         314 AA.
AC   A6NF89;
DE   RecName: Full=Olfactory receptor 6C6;
GN   Name=OR6C6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6C3_HUMAN             Reviewed;         311 AA.
AC   Q9NZP0;
DE   RecName: Full=Olfactory receptor 6C3;
DE   AltName: Full=HSA8;
GN   Name=OR6C3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR6K3_HUMAN             Reviewed;         331 AA.
AC   Q8NGY3; Q5VUV0; Q6IFR5;
DE   RecName: Full=Olfactory receptor 6K3;
DE   AltName: Full=Olfactory receptor OR1-18;
GN   Name=OR6K3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6K2_HUMAN             Reviewed;         324 AA.
AC   Q8NGY2; B9EH33; Q6IFR6;
DE   RecName: Full=Olfactory receptor 6K2;
DE   AltName: Full=Olfactory receptor OR1-17;
GN   Name=OR6K2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6K6_HUMAN             Reviewed;         343 AA.
AC   Q8NGW6; B9EIM8; Q5VUU9; Q6IFR4;
DE   RecName: Full=Olfactory receptor 6K6;
DE   AltName: Full=Olfactory receptor OR1-21;
GN   Name=OR6K6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6M1_HUMAN             Reviewed;         313 AA.
AC   Q8NGM8; B2RNK0; Q6IEW9; Q96R37;
DE   RecName: Full=Olfactory receptor 6M1;
DE   AltName: Full=Olfactory receptor OR11-271;
GN   Name=OR6M1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6N1_HUMAN             Reviewed;         312 AA.
AC   Q8NGY5; Q5VUU8; Q96R35;
DE   RecName: Full=Olfactory receptor 6N1;
GN   Name=OR6N1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6N2_HUMAN             Reviewed;         317 AA.
AC   Q8NGY6; Q6IFR2;
DE   RecName: Full=Olfactory receptor 6N2;
DE   AltName: Full=Olfactory receptor OR1-23;
GN   Name=OR6N2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6Q1_HUMAN             Reviewed;         317 AA.
AC   Q8NGQ2; B9EKW1; Q6IFH1; Q96R34;
DE   RecName: Full=Olfactory receptor 6Q1;
DE   AltName: Full=Olfactory receptor OR11-226;
GN   Name=OR6Q1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6S1_HUMAN             Reviewed;         331 AA.
AC   Q8NH40; Q6IFJ9;
DE   RecName: Full=Olfactory receptor 6S1;
DE   AltName: Full=Olfactory receptor OR14-37;
GN   Name=OR6S1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6T1_HUMAN             Reviewed;         323 AA.
AC   Q8NGN1; Q6IFE7;
DE   RecName: Full=Olfactory receptor 6T1;
DE   AltName: Full=Olfactory receptor OR11-277;
GN   Name=OR6T1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6V1_HUMAN             Reviewed;         313 AA.
AC   Q8N148; A4D2I0; B9EH48; Q6IF70;
DE   RecName: Full=Olfactory receptor 6V1;
DE   AltName: Full=Olfactory receptor OR7-3;
GN   Name=OR6V1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6X1_HUMAN             Reviewed;         312 AA.
AC   Q8NH79; B9EGW9; Q6IFA0;
DE   RecName: Full=Olfactory receptor 6X1;
DE   AltName: Full=Olfactory receptor OR11-270;
GN   Name=OR6X1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6Y1_HUMAN             Reviewed;         325 AA.
AC   Q8NGX8; Q6IFS0;
DE   RecName: Full=Olfactory receptor 6Y1;
DE   AltName: Full=Olfactory receptor 6Y2;
DE   AltName: Full=Olfactory receptor OR1-11;
GN   Name=OR6Y1; Synonyms=OR6Y2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR6P1_HUMAN             Reviewed;         317 AA.
AC   Q8NGX9; Q6IFR9;
DE   RecName: Full=Olfactory receptor 6P1;
DE   AltName: Full=Olfactory receptor OR1-12;
GN   Name=OR6P1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7A2_HUMAN             Reviewed;         310 AA.
AC   Q8NGA2; Q96R95;
DE   RecName: Full=Putative olfactory receptor 7A2;
DE   AltName: Full=Putative olfactory receptor 7A7;
GN   Name=OR7A2P; Synonyms=OR7A2, OR7A7;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7A5_HUMAN             Reviewed;         319 AA.
AC   Q15622; B2R682; Q6IFP1; Q96R96;
DE   RecName: Full=Olfactory receptor 7A5;
DE   AltName: Full=Olfactory receptor OR19-17;
DE   AltName: Full=Olfactory receptor TPCR92;
GN   Name=OR7A5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR7AH_HUMAN             Reviewed;         309 AA.
AC   O14581; Q6IFQ6; Q96R98;
DE   RecName: Full=Olfactory receptor 7A17;
GN   Name=OR7A17;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7AA_HUMAN             Reviewed;         309 AA.
AC   O76100; Q6IFP0; Q96R97;
DE   RecName: Full=Olfactory receptor 7A10;
DE   AltName: Full=OST027;
DE   AltName: Full=Olfactory receptor OR19-18;
GN   Name=OR7A10;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7C1_HUMAN             Reviewed;         320 AA.
AC   O76099; Q15621; Q6IFP2; Q96R94;
DE   RecName: Full=Olfactory receptor 7C1;
DE   AltName: Full=Olfactory receptor 7C4;
DE   AltName: Full=Olfactory receptor OR19-16;
DE   AltName: Full=Olfactory receptor TPCR86;
GN   Name=OR7C1; Synonyms=OR7C4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   OR7C2_HUMAN             Reviewed;         319 AA.
AC   O60412; O43881; Q6IFP9;
DE   RecName: Full=Olfactory receptor 7C2;
DE   AltName: Full=Olfactory receptor 19-18;
DE            Short=OR19-18;
DE   AltName: Full=Olfactory receptor 7C3;
DE   AltName: Full=Olfactory receptor OR19-22;
GN   Name=OR7C2; Synonyms=OR7C3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7D2_HUMAN             Reviewed;         312 AA.
AC   Q96RA2; Q6IFJ7; Q8N133;
DE   RecName: Full=Olfactory receptor 7D2;
DE   AltName: Full=HTPCRH03;
DE   AltName: Full=Olfactory receptor 19-4;
DE            Short=OR19-4;
DE   AltName: Full=Olfactory receptor OR19-10;
GN   Name=OR7D2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
//
ID   OR7D4_HUMAN             Reviewed;         312 AA.
AC   Q8NG98; A8CAH8; A8CAH9; A8CAI0; A8CAI1; B9EH79;
DE   RecName: Full=Olfactory receptor 7D4;
DE   AltName: Full=OR19-B;
DE   AltName: Full=Odorant receptor family subfamily D member 4RT;
DE   AltName: Full=Olfactory receptor OR19-7;
GN   Name=OR7D4; Synonyms=OR7D4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7G1_HUMAN             Reviewed;         311 AA.
AC   Q8NGA0; Q6IFJ5; Q96RA1;
DE   RecName: Full=Olfactory receptor 7G1;
DE   AltName: Full=Olfactory receptor 19-15;
DE            Short=OR19-15;
DE   AltName: Full=Olfactory receptor OR19-8;
GN   Name=OR7G1; Synonyms=OR7G1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7G2_HUMAN             Reviewed;         324 AA.
AC   Q8NG99; Q6IFJ4; Q96RA0;
DE   RecName: Full=Olfactory receptor 7G2;
DE   AltName: Full=OST260;
DE   AltName: Full=Olfactory receptor 19-13;
DE            Short=OR19-13;
DE   AltName: Full=Olfactory receptor OR19-6;
GN   Name=OR7G2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR7G3_HUMAN             Reviewed;         312 AA.
AC   Q8NG95; Q6IFJ6; Q96R99;
DE   RecName: Full=Olfactory receptor 7G3;
DE   AltName: Full=OST085;
DE   AltName: Full=Olfactory receptor OR19-9;
GN   Name=OR7G3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8A1_HUMAN             Reviewed;         326 AA.
AC   Q8NGG7; Q6IEW7; Q96RC6;
DE   RecName: Full=Olfactory receptor 8A1;
DE   AltName: Full=OST025;
DE   AltName: Full=Olfactory receptor OR11-318;
GN   Name=OR8A1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
//
ID   OR8B2_HUMAN             Reviewed;         313 AA.
AC   Q96RD0; Q8NGH2;
DE   RecName: Full=Olfactory receptor 8B2;
DE   AltName: Full=Olfactory receptor OR11-309;
GN   Name=OR8B2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8B4_HUMAN             Reviewed;         309 AA.
AC   Q96RC9; B2RNF8; Q6IFQ7;
DE   RecName: Full=Olfactory receptor 8B4;
DE   AltName: Full=Olfactory receptor OR11-315;
GN   Name=OR8B4; Synonyms=OR8B4P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8B3_HUMAN             Reviewed;         313 AA.
AC   Q8NGG8; Q6IFQ8; Q8NGH1;
DE   RecName: Full=Olfactory receptor 8B3;
DE   AltName: Full=Olfactory receptor OR11-311;
GN   Name=OR8B3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8B8_HUMAN             Reviewed;         311 AA.
AC   Q15620; A1L446; Q96RC8;
DE   RecName: Full=Olfactory receptor 8B8;
DE   AltName: Full=Olfactory receptor TPCR85;
DE   AltName: Full=Olfactory-like receptor JCG8;
GN   Name=OR8B8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR8BC_HUMAN             Reviewed;         310 AA.
AC   Q8NGG6; B2RNF6; Q6IEW8; Q96RC7;
DE   RecName: Full=Olfactory receptor 8B12;
DE   AltName: Full=Olfactory receptor OR11-317;
GN   Name=OR8B12;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8D2_HUMAN             Reviewed;         311 AA.
AC   Q9GZM6; B9EH49; Q6IFR0;
DE   RecName: Full=Olfactory receptor 8D2;
DE   AltName: Full=Olfactory receptor OR11-303;
DE   AltName: Full=Olfactory receptor-like protein JCG2;
GN   Name=OR8D2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8D1_HUMAN             Reviewed;         308 AA.
AC   Q8WZ84; B2RNL4; Q6IEW1; Q8NGH0;
DE   RecName: Full=Olfactory receptor 8D1;
DE   AltName: Full=OST004;
DE   AltName: Full=Olfactory receptor 8D3;
DE   AltName: Full=Olfactory receptor OR11-301;
DE   AltName: Full=Olfactory receptor-like protein JCG9;
GN   Name=OR8D1; Synonyms=OR8D3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8D4_HUMAN             Reviewed;         314 AA.
AC   Q8NGM9; Q6IFE9;
DE   RecName: Full=Olfactory receptor 8D4;
DE   AltName: Full=Olfactory receptor OR11-275;
GN   Name=OR8D4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8G2_HUMAN             Reviewed;         310 AA.
AC   Q15614; Q6IF38;
DE   RecName: Full=Olfactory receptor 8G2;
DE   AltName: Full=Olfactory receptor 8G4;
DE   AltName: Full=Olfactory receptor OR11-297;
DE   AltName: Full=Olfactory receptor TPCR120;
GN   Name=OR8G2; Synonyms=OR8G2P, OR8G4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR8G1_HUMAN             Reviewed;         311 AA.
AC   Q15617; Q8NG88;
DE   RecName: Full=Olfactory receptor 8G1;
DE   AltName: Full=Olfactory receptor OR11-281;
DE   AltName: Full=Olfactory receptor TPCR25;
GN   Name=OR8G1; Synonyms=OR8G1P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; NAS:UniProtKB.
DR   GO; GO:0050911; P:detection of chemical stimulus involved in sensory perception of smell; NAS:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; NAS:UniProtKB.
//
ID   OR8G5_HUMAN             Reviewed;         346 AA.
AC   Q8NG78; B2RND3; Q6IEU6;
DE   RecName: Full=Olfactory receptor 8G5;
DE   AltName: Full=Olfactory receptor 8G6;
DE   AltName: Full=Olfactory receptor OR11-298;
GN   Name=OR8G5; Synonyms=OR8G5P, OR8G6;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8H2_HUMAN             Reviewed;         312 AA.
AC   Q8N162; Q6IFC1;
DE   RecName: Full=Olfactory receptor 8H2;
DE   AltName: Full=Olfactory receptor OR11-171;
GN   Name=OR8H2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8H1_HUMAN             Reviewed;         311 AA.
AC   Q8NGG4; B2RNI7; Q6IFC5;
DE   RecName: Full=Olfactory receptor 8H1;
DE   AltName: Full=Olfactory receptor OR11-180;
GN   Name=OR8H1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8H3_HUMAN             Reviewed;         312 AA.
AC   Q8N146; Q6IFB7;
DE   RecName: Full=Olfactory receptor 8H3;
DE   AltName: Full=Olfactory receptor OR11-172;
GN   Name=OR8H3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8I2_HUMAN             Reviewed;         310 AA.
AC   Q8N0Y5; B2RNN4; Q6IFC0; Q96RC5;
DE   RecName: Full=Olfactory receptor 8I2;
DE   AltName: Full=Olfactory receptor OR11-170;
GN   Name=OR8I2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8J1_HUMAN             Reviewed;         316 AA.
AC   Q8NGP2; B2RNQ6; B9EH63; Q6IFC2; Q96RC3;
DE   RecName: Full=Olfactory receptor 8J1;
DE   AltName: Full=Olfactory receptor OR11-183;
GN   Name=OR8J1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8J2_HUMAN             Reviewed;         315 AA.
AC   Q8NGG1;
DE   RecName: Full=Olfactory receptor 8J2;
GN   Name=OR8J2; Synonyms=OR8J2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8J3_HUMAN             Reviewed;         315 AA.
AC   Q8NGG0; Q6IFB6; Q96RC2;
DE   RecName: Full=Olfactory receptor 8J3;
DE   AltName: Full=Olfactory receptor OR11-173;
GN   Name=OR8J3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8K1_HUMAN             Reviewed;         319 AA.
AC   Q8NGG5; B9EJB1; Q6IFC3; Q96RC1;
DE   RecName: Full=Olfactory receptor 8K1;
DE   AltName: Full=Olfactory receptor OR11-182;
GN   Name=OR8K1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8K3_HUMAN             Reviewed;         312 AA.
AC   Q8NH51; Q6IFC4;
DE   RecName: Full=Olfactory receptor 8K3;
DE   AltName: Full=Olfactory receptor OR11-181;
GN   Name=OR8K3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8K5_HUMAN             Reviewed;         307 AA.
AC   Q8NH50; Q6IFB5;
DE   RecName: Full=Olfactory receptor 8K5;
DE   AltName: Full=Olfactory receptor OR11-174;
GN   Name=OR8K5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8S1_HUMAN             Reviewed;         359 AA.
AC   Q8NH09;
DE   RecName: Full=Olfactory receptor 8S1;
GN   Name=OR8S1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8U1_HUMAN             Reviewed;         309 AA.
AC   Q8NH10;
DE   RecName: Full=Olfactory receptor 8U1;
GN   Name=OR8U1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8U8_HUMAN             Reviewed;         319 AA.
AC   P0C7N1;
DE   RecName: Full=Olfactory receptor 8U8;
GN   Name=OR8U8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR8U9_HUMAN             Reviewed;         309 AA.
AC   P0C7N5;
DE   RecName: Full=Olfactory receptor 8U9;
GN   Name=OR8U9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9A4_HUMAN             Reviewed;         314 AA.
AC   Q8NGU2; B9EGV6; Q6IFI4;
DE   RecName: Full=Olfactory receptor 9A4;
DE   AltName: Full=Olfactory receptor OR7-1;
GN   Name=OR9A4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9A1_HUMAN             Reviewed;         263 AA.
AC   Q8NGU1;
DE   RecName: Full=Putative olfactory receptor 9A1;
DE   AltName: Full=HSHTPRX06;
GN   Name=OR9A1P; Synonyms=OR9A1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9A2_HUMAN             Reviewed;         310 AA.
AC   Q8NGT5; B9EH51; Q6IF71; Q8NGD9;
DE   RecName: Full=Olfactory receptor 9A2;
DE   AltName: Full=Olfactory receptor OR7-2;
GN   Name=OR9A2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9G1_HUMAN             Reviewed;         305 AA.
AC   Q8NH87; Q6IEU9; Q8NGQ0;
DE   RecName: Full=Olfactory receptor 9G1;
DE   AltName: Full=Olfactory receptor 9G5;
DE   AltName: Full=Olfactory receptor OR11-114;
GN   Name=OR9G1; Synonyms=OR9G5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9G4_HUMAN             Reviewed;         327 AA.
AC   Q8NGQ1; Q6IF62; Q96RA9;
DE   RecName: Full=Olfactory receptor 9G4;
DE   AltName: Full=Olfactory receptor OR11-216;
GN   Name=OR9G4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9G9_HUMAN             Reviewed;         305 AA.
AC   P0C7N8;
DE   RecName: Full=Olfactory receptor 9G9;
GN   Name=OR9G9;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9K2_HUMAN             Reviewed;         335 AA.
AC   Q8NGE7; B9EH19; Q6IFD6;
DE   RecName: Full=Olfactory receptor 9K2;
DE   AltName: Full=Olfactory receptor OR12-2;
GN   Name=OR9K2;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9I1_HUMAN             Reviewed;         314 AA.
AC   Q8NGQ6; Q6IFH0; Q96RA8;
DE   RecName: Full=Olfactory receptor 9I1;
DE   AltName: Full=Olfactory receptor OR11-228;
GN   Name=OR9I1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9Q1_HUMAN             Reviewed;         310 AA.
AC   Q8NGQ5; Q2TAN3; Q96RA7;
DE   RecName: Full=Olfactory receptor 9Q1;
GN   Name=OR9Q1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   OR9Q2_HUMAN             Reviewed;         314 AA.
AC   Q8NGE9;
DE   RecName: Full=Olfactory receptor 9Q2;
GN   Name=OR9Q2; Synonyms=OR9Q2P;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   ORAI2_HUMAN             Reviewed;         254 AA.
AC   Q96SN7; Q6IA68; Q8WY94; Q9H9Y3;
DE   RecName: Full=Protein orai-2;
DE   AltName: Full=CAP-binding protein complex-interacting protein 2;
DE   AltName: Full=Transmembrane protein 142B;
GN   Name=ORAI2; Synonyms=C7orf19, CBCIP2, TMEM142B; ORFNames=PP1729;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   ORAI3_HUMAN             Reviewed;         295 AA.
AC   Q9BRQ5; Q96BI8;
DE   RecName: Full=Protein orai-3;
DE   AltName: Full=Transmembrane protein 142C;
GN   Name=ORAI3; Synonyms=TMEM142C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   ORAV1_HUMAN             Reviewed;         137 AA.
AC   Q8WV07; B2R4R2; Q8NFK0;
DE   RecName: Full=Oral cancer-overexpressed protein 1;
DE   AltName: Full=Tumor-amplified and overexpressed sequence 1;
GN   Name=ORAOV1; Synonyms=TAOS1;
//
ID   ORC1_HUMAN              Reviewed;         861 AA.
AC   Q13415; D3DQ34; Q13471; Q5T0F5;
DE   RecName: Full=Origin recognition complex subunit 1;
DE   AltName: Full=Replication control protein 1;
GN   Name=ORC1; Synonyms=ORC1L, PARC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
//
ID   ORC2_HUMAN              Reviewed;         577 AA.
AC   Q13416; Q13204; Q53TX5;
DE   RecName: Full=Origin recognition complex subunit 2;
GN   Name=ORC2; Synonyms=ORC2L;
DR   GO; GO:0003688; F:DNA replication origin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ORC3_HUMAN              Reviewed;         711 AA.
AC   Q9UBD5; A2A2T5; B4E025; Q13565; Q53GY6; Q5T159; Q6IUY7; Q86TN5;
AC   Q9UG44; Q9UNT6;
DE   RecName: Full=Origin recognition complex subunit 3;
DE   AltName: Full=Origin recognition complex subunit Latheo;
GN   Name=ORC3; Synonyms=LATHEO, ORC3L;
DR   GO; GO:0003688; F:DNA replication origin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0061351; P:neural precursor cell proliferation; IEA:Ensembl.
//
ID   ORC4_HUMAN              Reviewed;         436 AA.
AC   O43929; B7Z3D0; B7Z5F1; D3DP86; F5H069; Q96C42;
DE   RecName: Full=Origin recognition complex subunit 4;
GN   Name=ORC4; Synonyms=ORC4L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IMP:UniProtKB.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006270; P:DNA replication initiation; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   ORC5_HUMAN              Reviewed;         435 AA.
AC   O43913; A4D0P8; O60590; O95268;
DE   RecName: Full=Origin recognition complex subunit 5;
GN   Name=ORC5; Synonyms=ORC5L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   ORC6_HUMAN              Reviewed;         252 AA.
AC   Q9Y5N6; B3KN89;
DE   RecName: Full=Origin recognition complex subunit 6;
GN   Name=ORC6; Synonyms=ORC6L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   OREX_HUMAN              Reviewed;         131 AA.
AC   O43612;
DE   RecName: Full=Orexin;
DE   AltName: Full=Hypocretin;
DE            Short=Hcrt;
DE   Contains:
DE     RecName: Full=Orexin-A;
DE     AltName: Full=Hypocretin-1;
DE              Short=Hcrt1;
DE   Contains:
DE     RecName: Full=Orexin-B;
DE     AltName: Full=Hypocretin-2;
DE              Short=Hcrt2;
DE   Flags: Precursor;
GN   Name=HCRT; Synonyms=OX, PPORX, PPOX;
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0051970; P:negative regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0051971; P:positive regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   ORML1_HUMAN             Reviewed;         153 AA.
AC   Q9P0S3; B2R8W3; D3DPH9;
DE   RecName: Full=ORM1-like protein 1;
DE   AltName: Full=Adoplin-1;
GN   Name=ORMDL1; ORFNames=HSPC202;
DR   GO; GO:0006672; P:ceramide metabolic process; IMP:UniProtKB.
//
ID   ORML2_HUMAN             Reviewed;         153 AA.
AC   Q53FV1; B2RA58; Q7Z4E5; Q8NFX0; Q9P004;
DE   RecName: Full=ORM1-like protein 2;
DE   AltName: Full=Adoplin-2;
GN   Name=ORMDL2; ORFNames=HSPC160, MSTP095;
DR   GO; GO:0006672; P:ceramide metabolic process; IMP:UniProtKB.
//
ID   ORML3_HUMAN             Reviewed;         153 AA.
AC   Q8N138; B3KS83; Q6UY83;
DE   RecName: Full=ORM1-like protein 3;
GN   Name=ORMDL3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; IMP:UniProtKB.
//
ID   ORNT1_HUMAN             Reviewed;         301 AA.
AC   Q9Y619; Q5VZD8; Q9HC45;
DE   RecName: Full=Mitochondrial ornithine transporter 1;
DE   AltName: Full=Solute carrier family 25 member 15;
GN   Name=SLC25A15; Synonyms=ORNT1; ORFNames=SP1855;
DR   GO; GO:0000064; F:L-ornithine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0000066; P:mitochondrial ornithine transport; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
//
ID   ORNT2_HUMAN             Reviewed;         301 AA.
AC   Q9BXI2; Q496C1; Q6XUI0; Q8NFZ2;
DE   RecName: Full=Mitochondrial ornithine transporter 2;
DE   AltName: Full=Solute carrier family 25 member 2;
GN   Name=SLC25A2; Synonyms=ORNT2;
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0000050; P:urea cycle; TAS:Reactome.
//
ID   ORN_HUMAN               Reviewed;         237 AA.
AC   Q9Y3B8; B2R532; Q32Q18; Q53FT1; Q6FIC6; Q9UFY7;
DE   RecName: Full=Oligoribonuclease, mitochondrial;
DE            EC=3.1.-.-;
DE   AltName: Full=RNA exonuclease 2 homolog;
DE   AltName: Full=Small fragment nuclease;
DE   Flags: Precursor;
GN   Name=REXO2; Synonyms=SFN, SMFN; ORFNames=CGI-114;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:MGI.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IDA:MGI.
DR   GO; GO:0009117; P:nucleotide metabolic process; TAS:ProtInc.
//
ID   OS9_HUMAN               Reviewed;         667 AA.
AC   Q13438; A6NDD1; A6NFR7; A6NLB2; A8K5Q9; B4DE28; B4DPX1; B4E1I6;
AC   E7ENT8; E7EW91; F8VUH2; G3XA88; O00579; Q6IBL2; Q8IZ58; Q9BW99;
DE   RecName: Full=Protein OS-9;
DE   AltName: Full=Amplified in osteosarcoma 9;
DE   Flags: Precursor;
GN   Name=OS9;
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006621; P:protein retention in ER lumen; IDA:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
//
ID   OSB10_HUMAN             Reviewed;         764 AA.
AC   Q9BXB5; B4E212; Q9BTU5;
DE   RecName: Full=Oxysterol-binding protein-related protein 10;
DE            Short=ORP-10;
DE            Short=OSBP-related protein 10;
GN   Name=OSBPL10; Synonyms=ORP10, OSBP9;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSB11_HUMAN             Reviewed;         747 AA.
AC   Q9BXB4; A8K9I7;
DE   RecName: Full=Oxysterol-binding protein-related protein 11;
DE            Short=ORP-11;
DE            Short=OSBP-related protein 11;
GN   Name=OSBPL11; Synonyms=ORP11, OSBP12;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; IMP:BHF-UCL.
//
ID   OSBL1_HUMAN             Reviewed;         950 AA.
AC   Q9BXW6; B7Z7D3; Q9BZF5; Q9NW87;
DE   RecName: Full=Oxysterol-binding protein-related protein 1;
DE            Short=ORP-1;
DE            Short=OSBP-related protein 1;
GN   Name=OSBPL1A; Synonyms=ORP1, OSBP8, OSBPL1, OSBPL1B;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
//
ID   OSBL2_HUMAN             Reviewed;         480 AA.
AC   Q9H1P3; A8K736; Q6IBT0; Q9BZB1; Q9Y4B8;
DE   RecName: Full=Oxysterol-binding protein-related protein 2;
DE            Short=ORP-2;
DE            Short=OSBP-related protein 2;
GN   Name=OSBPL2; Synonyms=KIAA0772, ORP2;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSBL3_HUMAN             Reviewed;         887 AA.
AC   Q9H4L5; A4D167; A4D168; A4D169; A4D170; A4D171; A4D172; B8ZZ79;
AC   B8ZZP0; O14591; O43357; O43358; Q8N702; Q8N703; Q8N704; Q8NFH0;
AC   Q8NFH1; Q8NI12; Q8NI13; Q9BZF4; Q9UED6;
DE   RecName: Full=Oxysterol-binding protein-related protein 3;
DE            Short=ORP-3;
DE            Short=OSBP-related protein 3;
GN   Name=OSBPL3; Synonyms=KIAA0704, ORP3, OSBP3;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSBL5_HUMAN             Reviewed;         879 AA.
AC   Q9H0X9; A6NDP0; A6NJS8; Q54A90; Q8N596; Q9BZB0; Q9P1Z4;
DE   RecName: Full=Oxysterol-binding protein-related protein 5;
DE            Short=ORP-5;
DE            Short=OSBP-related protein 5;
DE   AltName: Full=Oxysterol-binding protein homolog 1;
GN   Name=OSBPL5; Synonyms=KIAA1534, OBPH1, ORP5;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0008142; F:oxysterol binding; NAS:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; NAS:UniProtKB.
DR   GO; GO:0030301; P:cholesterol transport; NAS:UniProtKB.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; NAS:UniProtKB.
//
ID   OSBL6_HUMAN             Reviewed;         934 AA.
AC   Q9BZF3; B4DTW1; C4AMC0; C4AME4; D3DPF6; D3DPF7; Q4ZG68; Q53T68;
AC   Q59H61; Q7Z4Q1; Q86V84; Q8N9T0; Q96SR1;
DE   RecName: Full=Oxysterol-binding protein-related protein 6;
DE            Short=ORP-6;
DE            Short=OSBP-related protein 6;
GN   Name=OSBPL6; Synonyms=ORP6;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSBL8_HUMAN             Reviewed;         889 AA.
AC   Q9BZF1; A8K1T2; E9PE66; E9PE68; Q52LQ3; Q68D75; Q8WXP8; Q9P277;
DE   RecName: Full=Oxysterol-binding protein-related protein 8;
DE            Short=ORP-8;
DE            Short=OSBP-related protein 8;
GN   Name=OSBPL8; Synonyms=KIAA1451, ORP8, OSBP10;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0010891; P:negative regulation of sequestering of triglyceride; IDA:BHF-UCL.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0090204; P:protein localization to nuclear pore; IEA:Ensembl.
//
ID   OSBL9_HUMAN             Reviewed;         736 AA.
AC   Q96SU4; B1AKJ8; B3KPQ4; D3DQ31; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17;
AC   Q8TAS8; Q96SK4; Q9H9X2;
DE   RecName: Full=Oxysterol-binding protein-related protein 9;
DE            Short=ORP-9;
DE            Short=OSBP-related protein 9;
GN   Name=OSBPL9; Synonyms=ORP9, OSBP4;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSBP1_HUMAN             Reviewed;         807 AA.
AC   P22059; Q6P524;
DE   RecName: Full=Oxysterol-binding protein 1;
GN   Name=OSBP; Synonyms=OSBP1;
DR   GO; GO:0008142; F:oxysterol binding; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSCP1_HUMAN             Reviewed;         389 AA.
AC   Q8WVF1; A6NHM5; A6NHS9; A6NIN9; Q4AEJ0; Q8N7G2; Q8TDF1;
DE   RecName: Full=Protein OSCP1;
DE            Short=hOSCP1;
DE   AltName: Full=Organic solute transport protein 1;
DE   AltName: Full=Oxidored-nitro domain-containing protein 1;
GN   Name=OSCP1; Synonyms=C1orf102, NOR1;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   OSCAR_HUMAN             Reviewed;         282 AA.
AC   Q8IYS5; B7WNS2; Q5GRG5; Q8N763; Q8NHL4; Q8WXQ0; Q8WXQ1; Q8WXQ2;
DE   RecName: Full=Osteoclast-associated immunoglobulin-like receptor;
DE            Short=Osteoclast-associated receptor;
DE            Short=hOSCAR;
DE   AltName: Full=Polymeric immunoglobulin receptor 3;
DE            Short=PIgR-3;
DE            Short=PIgR3;
DE            Short=Poly-Ig receptor 3;
DE   Flags: Precursor;
GN   Name=OSCAR;
//
ID   OSBL7_HUMAN             Reviewed;         842 AA.
AC   Q9BZF2; D3DTT6;
DE   RecName: Full=Oxysterol-binding protein-related protein 7;
DE            Short=ORP-7;
DE            Short=OSBP-related protein 7;
GN   Name=OSBPL7; Synonyms=ORP7;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0071397; P:cellular response to cholesterol; IMP:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:1901800; P:positive regulation of proteasomal protein catabolic process; IMP:BHF-UCL.
//
ID   OSBP2_HUMAN             Reviewed;         916 AA.
AC   Q969R2; B0QYG1; B4DKE4; O60396; Q0VF99; Q9BY96; Q9BZF0;
DE   RecName: Full=Oxysterol-binding protein 2;
DE   AltName: Full=Oxysterol-binding protein-related protein 4;
DE            Short=ORP-4;
DE            Short=OSBP-related protein 4;
GN   Name=OSBP2; Synonyms=KIAA1664, ORP4, OSBPL4;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   OSER1_HUMAN             Reviewed;         292 AA.
AC   Q9NX31; B2RCK4; O95912; Q9NZ84; Q9P0R8;
DE   RecName: Full=Oxidative stress-responsive serine-rich protein 1;
DE   AltName: Full=Oxidative stress-responsive protein 1;
DE   AltName: Full=Peroxide-inducible transcript 1 protein;
GN   Name=OSER1; Synonyms=C20orf111; ORFNames=BM-038, HSPC168, HSPC207;
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
//
ID   OSGEP_HUMAN             Reviewed;         335 AA.
AC   Q9NPF4; Q6IAC3;
DE   RecName: Full=Probable tRNA N6-adenosine threonylcarbamoyltransferase;
DE            EC=2.6.99.4;
DE   AltName: Full=N6-L-threonylcarbamoyladenine synthase;
DE            Short=t(6)A synthase;
DE   AltName: Full=O-sialoglycoprotein endopeptidase;
DE            Short=hOSGEP;
DE   AltName: Full=t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP;
DE   AltName: Full=tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP;
GN   Name=OSGEP; Synonyms=GCPL1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070526; P:threonylcarbamoyladenosine biosynthetic process; IEA:UniProtKB-HAMAP.
//
ID   OSGI1_HUMAN             Reviewed;         560 AA.
AC   Q9UJX0; Q52M33; Q86UQ1; Q96S88; Q9BZ70;
DE   RecName: Full=Oxidative stress-induced growth inhibitor 1;
DE   AltName: Full=Ovary, kidney and liver protein 38;
DE            Short=huOKL38;
DE   AltName: Full=Pregnancy-induced growth inhibitor OKL38;
GN   Name=OSGIN1; Synonyms=OKL38;
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
//
ID   OSGI2_HUMAN             Reviewed;         505 AA.
AC   Q9Y236;
DE   RecName: Full=Oxidative stress-induced growth inhibitor 2;
DE   AltName: Full=hT41;
GN   Name=OSGIN2; Synonyms=C8orf1;
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   OSGP2_HUMAN             Reviewed;         414 AA.
AC   Q9H4B0; Q96EV9; Q96NH5;
DE   RecName: Full=Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial;
DE            EC=2.6.99.4;
DE   AltName: Full=N6-L-threonylcarbamoyladenine synthase;
DE            Short=t(6)A synthase;
DE   AltName: Full=O-sialoglycoprotein endopeptidase-like protein 1;
DE   AltName: Full=t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1;
DE   AltName: Full=tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1;
DE   Flags: Precursor;
GN   Name=OSGEPL1; Synonyms=GCP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:UniProtKB-HAMAP.
DR   GO; GO:0070526; P:threonylcarbamoyladenosine biosynthetic process; IEA:UniProtKB-HAMAP.
//
ID   OSMR_HUMAN              Reviewed;         979 AA.
AC   Q99650; Q6P4E8; Q96QJ6;
DE   RecName: Full=Oncostatin-M-specific receptor subunit beta;
DE   AltName: Full=Interleukin-31 receptor subunit beta;
DE            Short=IL-31 receptor subunit beta;
DE            Short=IL-31R subunit beta;
DE            Short=IL-31R-beta;
DE            Short=IL-31RB;
DE   Flags: Precursor;
GN   Name=OSMR; Synonyms=OSMRB;
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0004924; F:oncostatin-M receptor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0038165; P:oncostatin-M-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IC:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IGI:BHF-UCL.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
//
ID   OSR2_HUMAN              Reviewed;         312 AA.
AC   Q8N2R0; A8K626; B4E3B7; Q96AM6; Q96LB6; Q96LB7;
DE   RecName: Full=Protein odd-skipped-related 2;
GN   Name=OSR2;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0060349; P:bone morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0072498; P:embryonic skeletal joint development; ISS:BHF-UCL.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0036023; P:embryonic skeletal limb joint morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0060322; P:head development; ISS:BHF-UCL.
DR   GO; GO:0001823; P:mesonephros development; ISS:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; ISS:UniProtKB.
DR   GO; GO:0042474; P:middle ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0042476; P:odontogenesis; ISS:UniProtKB.
DR   GO; GO:0033687; P:osteoblast proliferation; ISS:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:2000543; P:positive regulation of gastrulation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0048793; P:pronephros development; IEA:Ensembl.
//
ID   OSR1_HUMAN              Reviewed;         266 AA.
AC   Q8TAX0; B3KV97; D6W521;
DE   RecName: Full=Protein odd-skipped-related 1;
GN   Name=OSR1; Synonyms=ODD;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0072111; P:cell proliferation involved in kidney development; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0072498; P:embryonic skeletal joint development; ISS:BHF-UCL.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0036023; P:embryonic skeletal limb joint morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0008406; P:gonad development; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0048389; P:intermediate mesoderm development; IEA:Ensembl.
DR   GO; GO:0072143; P:mesangial cell development; ISS:UniProtKB.
DR   GO; GO:0072180; P:mesonephric duct morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001823; P:mesonephros development; ISS:UniProtKB.
DR   GO; GO:0090094; P:metanephric cap mesenchymal cell proliferation involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0072207; P:metanephric epithelium development; ISS:UniProtKB.
DR   GO; GO:0072239; P:metanephric glomerulus vasculature development; ISS:UniProtKB.
DR   GO; GO:0072259; P:metanephric interstitial cell development; ISS:UniProtKB.
DR   GO; GO:0072162; P:metanephric mesenchymal cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0072133; P:metanephric mesenchyme morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072234; P:metanephric nephron tubule development; ISS:UniProtKB.
DR   GO; GO:0072208; P:metanephric smooth muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0042474; P:middle ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072183; P:negative regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0042476; P:odontogenesis; ISS:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0072268; P:pattern specification involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; ISS:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.
DR   GO; GO:0048793; P:pronephros development; IMP:UniProtKB.
DR   GO; GO:0072184; P:renal vesicle progenitor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072168; P:specification of anterior mesonephric tubule identity; ISS:UniProtKB.
DR   GO; GO:0072169; P:specification of posterior mesonephric tubule identity; ISS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0072190; P:ureter urothelium development; ISS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; ISS:UniProtKB.
//
ID   OST48_HUMAN             Reviewed;         456 AA.
AC   P39656; B2RDQ4; O43244; Q5VWA5; Q8NI93; Q9BUI2;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit;
DE            Short=DDOST 48 kDa subunit;
DE            Short=Oligosaccharyl transferase 48 kDa subunit;
DE            EC=2.4.99.18;
DE   Flags: Precursor;
GN   Name=DDOST; Synonyms=KIAA0115, OST48; ORFNames=OK/SW-cl.45;
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; ISS:UniProtKB.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IC:HGNC.
DR   GO; GO:0034097; P:response to cytokine; IDA:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   OST4_HUMAN              Reviewed;          37 AA.
AC   P0C6T2;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4;
GN   Name=OST4;
//
ID   OSTA_HUMAN              Reviewed;         340 AA.
AC   Q86UW1; Q6ZMC7;
DE   RecName: Full=Organic solute transporter subunit alpha;
DE            Short=OST-alpha;
DE   AltName: Full=Solute carrier family 51 subunit alpha;
GN   Name=SLC51A; Synonyms=OSTA;
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IDA:UniProtKB.
DR   GO; GO:0015721; P:bile acid and bile salt transport; ISS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEP:UniProtKB.
//
ID   OSTB_HUMAN              Reviewed;         128 AA.
AC   Q86UW2; Q3SYF5;
DE   RecName: Full=Organic solute transporter subunit beta;
DE            Short=OST-beta;
DE   AltName: Full=Solute carrier family 51 subunit beta;
GN   Name=SLC51B; Synonyms=OSTB;
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:Ensembl.
DR   GO; GO:0015721; P:bile acid and bile salt transport; ISS:UniProtKB.
DR   GO; GO:0070863; P:positive regulation of protein exit from endoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0060050; P:positive regulation of protein glycosylation; ISS:UniProtKB.
DR   GO; GO:0090314; P:positive regulation of protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; ISS:UniProtKB.
//
ID   OSTCN_HUMAN             Reviewed;         100 AA.
AC   P02818; Q5TCK6;
DE   RecName: Full=Osteocalcin;
DE   AltName: Full=Bone Gla protein;
DE            Short=BGP;
DE   AltName: Full=Gamma-carboxyglutamic acid-containing protein;
DE   Flags: Precursor;
GN   Name=BGLAP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0046848; F:hydroxyapatite binding; NAS:UniProtKB.
DR   GO; GO:0008147; F:structural constituent of bone; NAS:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0030282; P:bone mineralization; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071305; P:cellular response to vitamin D; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; NAS:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:InterPro.
DR   GO; GO:0045124; P:regulation of bone resorption; NAS:UniProtKB.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; NAS:UniProtKB.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0033594; P:response to hydroxyisoflavone; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEP:BHF-UCL.
DR   GO; GO:0032571; P:response to vitamin K; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   OSTC_HUMAN              Reviewed;         149 AA.
AC   Q9NRP0; A8MYS2; B2R5H1; D6RH22; Q9P075; Q9P1R4;
DE   RecName: Full=Oligosaccharyltransferase complex subunit OSTC;
DE   AltName: Full=Hydrophobic protein HSF-28;
GN   Name=OSTC; ORFNames=DC2, HDCMD45P, HSPC307;
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IC:HGNC.
//
ID   OSTF1_HUMAN             Reviewed;         214 AA.
AC   Q92882; Q5W126; Q96IJ4;
DE   RecName: Full=Osteoclast-stimulating factor 1;
GN   Name=OSTF1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   OSTN_HUMAN              Reviewed;         133 AA.
AC   P61366; A1A4U3;
DE   RecName: Full=Osteocrin;
DE   AltName: Full=Musclin;
DE   Flags: Precursor;
GN   Name=OSTN;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0003416; P:endochondral bone growth; IEA:Ensembl.
DR   GO; GO:0046325; P:negative regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
//
ID   OSTM1_HUMAN             Reviewed;         334 AA.
AC   Q86WC4; E1P5E3; Q5R391; Q6PCA7; Q7RTW6; Q8NC29; Q8TC82; Q9Y2S9;
DE   RecName: Full=Osteopetrosis-associated transmembrane protein 1;
DE   AltName: Full=Chloride channel 7 beta subunit;
DE   Flags: Precursor;
GN   Name=OSTM1; Synonyms=GL; ORFNames=HSPC019, UNQ6098/PRO21201;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   OSTP_HUMAN              Reviewed;         314 AA.
AC   P10451; B2RDA1; Q15681; Q15682; Q15683; Q4W597; Q567T5; Q8NBK2;
AC   Q96IZ1;
DE   RecName: Full=Osteopontin;
DE   AltName: Full=Bone sialoprotein 1;
DE   AltName: Full=Nephropontin;
DE   AltName: Full=Secreted phosphoprotein 1;
DE            Short=SPP-1;
DE   AltName: Full=Urinary stone protein;
DE   AltName: Full=Uropontin;
DE   Flags: Precursor;
GN   Name=SPP1; Synonyms=BNSP, OPN; ORFNames=PSEC0156;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0046697; P:decidualization; TAS:BHF-UCL.
DR   GO; GO:0007566; P:embryo implantation; TAS:BHF-UCL.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0048685; P:negative regulation of collateral sprouting of intact axon in response to injury; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IDA:BHF-UCL.
//
ID   OTC_HUMAN               Reviewed;         354 AA.
AC   P00480; A8K9P2; D3DWB0; Q3KNR1; Q6B0I1; Q9NYJ5;
DE   RecName: Full=Ornithine carbamoyltransferase, mitochondrial;
DE            EC=2.1.3.3;
DE   AltName: Full=Ornithine transcarbamylase;
DE            Short=OTCase;
DE   Flags: Precursor;
GN   Name=OTC;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0004585; F:ornithine carbamoyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0042301; F:phosphate ion binding; IEA:Ensembl.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0097272; P:ammonia homeostasis; IMP:BHF-UCL.
DR   GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019240; P:citrulline biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007494; P:midgut development; IEA:Ensembl.
DR   GO; GO:0006593; P:ornithine catabolic process; IDA:BHF-UCL.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:Ensembl.
DR   GO; GO:0070781; P:response to biotin; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000050; P:urea cycle; IDA:BHF-UCL.
//
ID   OTOAN_HUMAN             Reviewed;        1153 AA.
AC   Q7RTW8; A1L3A8; A2VDI0; B3KWU3; E9PF51; Q8NA86; Q96M76;
DE   RecName: Full=Otoancorin;
DE   Flags: Precursor;
GN   Name=OTOA;
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   OTOF_HUMAN              Reviewed;        1997 AA.
AC   Q9HC10; B4DJX0; B5MCC1; B9A0H6; Q53R90; Q9HC08; Q9HC09; Q9Y650;
DE   RecName: Full=Otoferlin;
DE   AltName: Full=Fer-1-like protein 2;
GN   Name=OTOF; Synonyms=FER1L2;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB.
//
ID   OTOGL_HUMAN             Reviewed;        2332 AA.
AC   Q3ZCN5; F8W0C3; Q495U8; Q8N8G5; Q8NC28;
DE   RecName: Full=Otogelin-like protein;
DE   Flags: Precursor;
GN   Name=OTOGL; Synonyms=C12orf64;
DR   GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:InterPro.
DR   GO; GO:0046373; P:L-arabinose metabolic process; IEA:InterPro.
//
ID   OTOG_HUMAN              Reviewed;        2925 AA.
AC   Q6ZRI0; A8MTX6; A8MUJ0; B7WPC4;
DE   RecName: Full=Otogelin;
DE   Flags: Precursor;
GN   Name=OTOG; Synonyms=OTGN;
DR   GO; GO:0046556; F:alpha-L-arabinofuranosidase activity; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0046373; P:L-arabinose metabolic process; IEA:InterPro.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   OTOL1_HUMAN             Reviewed;         477 AA.
AC   A6NHN0;
DE   RecName: Full=Otolin-1;
DE   Flags: Precursor;
GN   Name=OTOL1;
//
ID   OTOP2_HUMAN             Reviewed;         562 AA.
AC   Q7RTS6;
DE   RecName: Full=Otopetrin-2;
GN   Name=OTOP2;
//
ID   OTOP3_HUMAN             Reviewed;         596 AA.
AC   Q7RTS5;
DE   RecName: Full=Otopetrin-3;
GN   Name=OTOP3;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
//
ID   OTOR_HUMAN              Reviewed;         128 AA.
AC   Q9NRC9; D3DW22; Q3MIU6;
DE   RecName: Full=Otoraplin;
DE   AltName: Full=Fibrocyte-derived protein;
DE   AltName: Full=Melanoma inhibitory activity-like protein;
DE   Flags: Precursor;
GN   Name=OTOR; Synonyms=FDP, MIAL; ORFNames=UNQ3054/PRO9873;
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   OTOP1_HUMAN             Reviewed;         612 AA.
AC   Q7RTM1; A1L476;
DE   RecName: Full=Otopetrin-1;
GN   Name=OTOP1;
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0009590; P:detection of gravity; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
//
ID   OTOSP_HUMAN             Reviewed;          89 AA.
AC   Q8NHW6; Q53SW6;
DE   RecName: Full=Otospiralin;
DE   Flags: Precursor;
GN   Name=OTOS; Synonyms=OTOSP;
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   OTP_HUMAN               Reviewed;         325 AA.
AC   Q5XKR4;
DE   RecName: Full=Homeobox protein orthopedia;
GN   Name=OTP;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021979; P:hypothalamus cell differentiation; IEA:Ensembl.
DR   GO; GO:0021985; P:neurohypophysis development; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   OTU1_HUMAN              Reviewed;         348 AA.
AC   Q5VVQ6; B2RNX3; Q5VVQ5; Q6ZRS6; Q86T63; Q9P1L8;
DE   RecName: Full=Ubiquitin thioesterase OTU1;
DE            EC=3.4.19.12;
DE   AltName: Full=DUBA-8;
DE   AltName: Full=HIV-1-induced protease 7;
DE            Short=HIN-7;
DE            Short=HsHIN7;
DE   AltName: Full=OTU domain-containing protein 2;
GN   Name=YOD1; Synonyms=DUBA8, HIN7, OTUD2; ORFNames=PRO0907;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:1990167; P:protein K27-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0035523; P:protein K29-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:1990168; P:protein K33-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
//
ID   OTU6A_HUMAN             Reviewed;         288 AA.
AC   Q7L8S5; B2RPB7;
DE   RecName: Full=OTU domain-containing protein 6A;
DE            EC=3.4.19.12;
DE   AltName: Full=DUBA-2;
GN   Name=OTUD6A; Synonyms=DUBA2;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:1990167; P:protein K27-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0035523; P:protein K29-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:1990168; P:protein K33-linked deubiquitination; IDA:UniProtKB.
//
ID   OTU6B_HUMAN             Reviewed;         293 AA.
AC   Q8N6M0; A8K6I1; Q9NTA4; Q9Y387;
DE   RecName: Full=OTU domain-containing protein 6B;
DE            EC=3.4.19.12;
DE   AltName: Full=DUBA-5;
GN   Name=OTUD6B; Synonyms=DUBA5; ORFNames=CGI-77;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
//
ID   OTU7A_HUMAN             Reviewed;         926 AA.
AC   Q8TE49; Q8IWK5;
DE   RecName: Full=OTU domain-containing protein 7A;
DE            EC=3.4.19.12;
DE   AltName: Full=Zinc finger protein Cezanne 2;
GN   Name=OTUD7A; Synonyms=C15orf16, CEZANNE2, OTUD7;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
//
ID   OTU7B_HUMAN             Reviewed;         843 AA.
AC   Q6GQQ9; B7Z643; D3DUZ8; Q5SZ60; Q8WWA7; Q9NQ53; Q9UFF4;
DE   RecName: Full=OTU domain-containing protein 7B;
DE            EC=3.4.19.12;
DE   AltName: Full=Cellular zinc finger anti-NF-kappa-B protein;
DE   AltName: Full=Zinc finger A20 domain-containing protein 1;
DE   AltName: Full=Zinc finger protein Cezanne;
GN   Name=OTUD7B; Synonyms=ZA20D1;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002385; P:mucosal immune response; ISS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:HGNC.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; ISS:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
//
ID   OTUB1_HUMAN             Reviewed;         271 AA.
AC   Q96FW1; Q32Q78; Q96II3; Q9NXQ4; Q9P0B8;
DE   RecName: Full=Ubiquitin thioesterase OTUB1;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme OTUB1;
DE   AltName: Full=OTU domain-containing ubiquitin aldehyde-binding protein 1;
DE   AltName: Full=Otubain-1;
DE            Short=hOTU1;
DE   AltName: Full=Ubiquitin-specific-processing protease OTUB1;
GN   Name=OTUB1; Synonyms=OTB1, OTU1; ORFNames=HSPC263;
DR   GO; GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:2000780; P:negative regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:1901315; P:negative regulation of histone H2A K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
//
ID   OTUB2_HUMAN             Reviewed;         234 AA.
AC   Q96DC9; Q6IA10; Q9H6T1;
DE   RecName: Full=Ubiquitin thioesterase OTUB2;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme OTUB2;
DE   AltName: Full=OTU domain-containing ubiquitin aldehyde-binding protein 2;
DE   AltName: Full=Otubain-2;
DE   AltName: Full=Ubiquitin-specific-processing protease OTUB2;
GN   Name=OTUB2; Synonyms=C14orf137, OTB2, OTU2;
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IMP:UniProtKB.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
//
ID   OTUD1_HUMAN             Reviewed;         481 AA.
AC   Q5VV17;
DE   RecName: Full=OTU domain-containing protein 1;
DE            EC=3.4.19.12;
DE   AltName: Full=DUBA-7;
GN   Name=OTUD1; Synonyms=DUBA7, OTDC1;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
//
ID   OTUD3_HUMAN             Reviewed;         398 AA.
AC   Q5T2D3; O75047;
DE   RecName: Full=OTU domain-containing protein 3;
DE            EC=3.4.19.12;
GN   Name=OTUD3; Synonyms=KIAA0459;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0044313; P:protein K6-linked deubiquitination; IDA:UniProtKB.
//
ID   OTUD4_HUMAN             Reviewed;        1114 AA.
AC   Q01804; B4DYS4; Q147U2; Q1ZYK1; Q6PG39; Q96MQ5; Q9NT94; Q9UPV6;
DE   RecName: Full=OTU domain-containing protein 4;
DE            EC=3.4.19.12;
DE   AltName: Full=HIV-1-induced protein HIN-1;
GN   Name=OTUD4; Synonyms=HIN1, KIAA1046;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
//
ID   OTUD5_HUMAN             Reviewed;         571 AA.
AC   Q96G74; B4DGG7; G5E9D7; Q4KMN9; Q8N6T5; Q9H650; Q9H9U0; Q9NT65;
DE   RecName: Full=OTU domain-containing protein 5;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme A;
DE            Short=DUBA;
GN   Name=OTUD5;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
//
ID   OTUL_HUMAN              Reviewed;         352 AA.
AC   Q96BN8; D3DTD3; Q8NAS0; Q96IA3;
DE   RecName: Full=Ubiquitin thioesterase otulin;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme otulin;
DE   AltName: Full=OTU domain-containing deubiquitinase with linear linkage specificity;
DE   AltName: Full=Ubiquitin thioesterase Gumby;
GN   Name=OTULIN; Synonyms=FAM105B;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IMP:UniProtKB.
DR   GO; GO:1990108; P:protein linear deubiquitination; IDA:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
//
ID   OTX1_HUMAN              Reviewed;         354 AA.
AC   P32242; A6NHA2; B3KTJ4; Q53TG6;
DE   RecName: Full=Homeobox protein OTX1;
DE   AltName: Full=Orthodenticle homolog 1;
GN   Name=OTX1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048852; P:diencephalon morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0022037; P:metencephalon development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   OTX2_HUMAN              Reviewed;         289 AA.
AC   P32243; B2RAN5; Q6GTV3; Q9HAW3; Q9P2R1;
DE   RecName: Full=Homeobox protein OTX2;
DE   AltName: Full=Orthodenticle homolog 2;
GN   Name=OTX2;
DR   GO; GO:0008190; F:eukaryotic initiation factor 4E binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IDA:UniProtKB.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0048852; P:diencephalon morphogenesis; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0042706; P:eye photoreceptor cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; TAS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0022037; P:metencephalon development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; TAS:UniProtKB.
DR   GO; GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.
DR   GO; GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0090009; P:primitive streak formation; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; TAS:UniProtKB.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
//
ID   OVCA2_HUMAN             Reviewed;         227 AA.
AC   Q8WZ82; Q86XN3; Q8IW87; Q9UCX9;
DE   RecName: Full=Ovarian cancer-associated gene 2 protein;
GN   Name=OVCA2;
DR   GO; GO:0016787; F:hydrolase activity; NAS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; NAS:GOC.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:UniProtKB.
//
ID   OVCH1_HUMAN             Reviewed;        1134 AA.
AC   Q7RTY7;
DE   RecName: Full=Ovochymase-1;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=OVCH1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   OVCH2_HUMAN             Reviewed;         564 AA.
AC   Q7RTZ1;
DE   RecName: Full=Ovochymase-2;
DE            EC=3.4.21.-;
DE   AltName: Full=Oviductin;
DE   Flags: Precursor;
GN   Name=OVCH2; Synonyms=OVTN;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   OVGP1_HUMAN             Reviewed;         678 AA.
AC   Q12889; A0AV19; B9EGE1; Q15841;
DE   RecName: Full=Oviduct-specific glycoprotein;
DE   AltName: Full=Estrogen-dependent oviduct protein;
DE   AltName: Full=Mucin-9;
DE   AltName: Full=Oviductal glycoprotein;
DE   AltName: Full=Oviductin;
DE   Flags: Precursor;
GN   Name=OVGP1; Synonyms=MUC9, OGP;
DR   GO; GO:0004568; F:chitinase activity; IEA:InterPro.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:InterPro.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   OVOL1_HUMAN             Reviewed;         267 AA.
AC   O14753; Q6PCB1;
DE   RecName: Full=Putative transcription factor Ovo-like 1;
DE            Short=hOvo1;
GN   Name=OVOL1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:1901994; P:negative regulation of meiotic cell cycle phase transition; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   OVOS1_HUMAN             Reviewed;        1185 AA.
AC   Q6IE37;
DE   RecName: Full=Ovostatin homolog 1;
DE   Flags: Precursor;
GN   Name=OVOS1;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   OVOL3_HUMAN             Reviewed;         214 AA.
AC   O00110;
DE   RecName: Full=Putative transcription factor ovo-like protein 3;
GN   Name=OVOL3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   OVOS2_HUMAN             Reviewed;        1432 AA.
AC   Q6IE36;
DE   RecName: Full=Ovostatin homolog 2;
DE   Flags: Precursor;
GN   Name=OVOS2;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   OVOL2_HUMAN             Reviewed;         275 AA.
AC   Q9BRP0; Q5T8B4; Q9BX22; Q9HA54; Q9Y4M0;
DE   RecName: Full=Transcription factor Ovo-like 2;
DE            Short=hOvo2;
DE   AltName: Full=Zinc finger protein 339;
GN   Name=OVOL2; Synonyms=ZNF339;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0060214; P:endocardium formation; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0001842; P:neural fold formation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.
DR   GO; GO:0010837; P:regulation of keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   OX1R_HUMAN              Reviewed;         425 AA.
AC   O43613; A8K3A6; Q9HBV6;
DE   RecName: Full=Orexin receptor type 1;
DE            Short=Ox-1-R;
DE            Short=Ox1-R;
DE            Short=Ox1R;
DE   AltName: Full=Hypocretin receptor type 1;
GN   Name=HCRTR1;
DR   GuidetoPHARMACOLOGY; 321; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0016499; F:orexin receptor activity; IEA:InterPro.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   OX26_HUMAN              Reviewed;         136 AA.
AC   P83859; A3KFJ6; Q495K6;
DE   RecName: Full=Orexigenic neuropeptide QRFP;
DE   AltName: Full=P518;
DE   Contains:
DE     RecName: Full=QRF-amide;
DE     AltName: Full=Neuropeptide RF-amide;
DE     AltName: Full=Pyroglutamylated arginine-phenylalanine-amide peptide;
DE   Flags: Precursor;
GN   Name=QRFP;
DR   GO; GO:0005184; F:neuropeptide hormone activity; IDA:UniProtKB.
DR   GO; GO:0031854; F:orexigenic neuropeptide QRFP receptor binding; ISS:UniProtKB.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045777; P:positive regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0060259; P:regulation of feeding behavior; ISS:UniProtKB.
//
ID   OX2G_HUMAN              Reviewed;         278 AA.
AC   P41217; B3KQI1; B4DLW9; D3DN65; Q6J2Q6; Q6PIQ4; Q8TB85; Q9H3J3;
DE   RecName: Full=OX-2 membrane glycoprotein;
DE   AltName: CD_antigen=CD200;
DE   Flags: Precursor;
GN   Name=CD200; Synonyms=MOX1, MOX2; ORFNames=My033;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   OX2R_HUMAN              Reviewed;         444 AA.
AC   O43614; Q5VTM0;
DE   RecName: Full=Orexin receptor type 2;
DE            Short=Ox-2-R;
DE            Short=Ox2-R;
DE            Short=Ox2R;
DE   AltName: Full=Hypocretin receptor type 2;
GN   Name=HCRTR2;
DR   GuidetoPHARMACOLOGY; 322; -.
DR   GO; GO:0008188; F:neuropeptide receptor activity; TAS:ProtInc.
DR   GO; GO:0016499; F:orexin receptor activity; IEA:Ensembl.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0022410; P:circadian sleep/wake cycle process; IEA:InterPro.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   OXA1L_HUMAN             Reviewed;         435 AA.
AC   Q15070; B4DPA2;
DE   RecName: Full=Mitochondrial inner membrane protein OXA1L;
DE   AltName: Full=Hsa;
DE   AltName: Full=OXA1Hs;
DE   AltName: Full=Oxidase assembly 1-like protein;
DE            Short=OXA1-like protein;
DE   Flags: Precursor;
GN   Name=OXA1L;
DR   GO; GO:0097177; F:mitochondrial ribosome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0009060; P:aerobic respiration; IMP:UniProtKB.
DR   GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IMP:UniProtKB.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0097031; P:mitochondrial respiratory chain complex I biogenesis; IMP:UniProtKB.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; IMP:UniProtKB.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IMP:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; NAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0051205; P:protein insertion into membrane; IEA:InterPro.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
//
ID   OXDA_HUMAN              Reviewed;         347 AA.
AC   P14920; B2R7I5; Q16758; Q8N6R2;
DE   RecName: Full=D-amino-acid oxidase;
DE            Short=DAAO;
DE            Short=DAMOX;
DE            Short=DAO;
DE            EC=1.4.3.3;
GN   Name=DAO; Synonyms=DAMOX;
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0003884; F:D-amino-acid oxidase activity; IDA:UniProtKB.
DR   GO; GO:0071949; F:FAD binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0055130; P:D-alanine catabolic process; IDA:UniProtKB.
DR   GO; GO:0036088; P:D-serine catabolic process; IDA:UniProtKB.
DR   GO; GO:0070178; P:D-serine metabolic process; IDA:UniProtKB.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046487; P:glyoxylate metabolic process; TAS:Reactome.
DR   GO; GO:0006551; P:leucine metabolic process; IEA:Ensembl.
DR   GO; GO:0006562; P:proline catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   OXDD_HUMAN              Reviewed;         341 AA.
AC   Q99489; A8KAG4; Q5JXM4; Q5JXM5; Q5JXM6; Q8N552;
DE   RecName: Full=D-aspartate oxidase;
DE            Short=DASOX;
DE            Short=DDO;
DE            EC=1.4.3.1;
GN   Name=DDO;
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0008445; F:D-aspartate oxidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006533; P:aspartate catabolic process; IDA:UniProtKB.
DR   GO; GO:0006531; P:aspartate metabolic process; IEA:Ensembl.
DR   GO; GO:0019478; P:D-amino acid catabolic process; IDA:UniProtKB.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0007320; P:insemination; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
//
ID   OXGR1_HUMAN             Reviewed;         337 AA.
AC   Q96P68; Q5T5A7; Q86TL1;
DE   RecName: Full=2-oxoglutarate receptor 1;
DE   AltName: Full=Alpha-ketoglutarate receptor 1;
DE   AltName: Full=G-protein coupled receptor 80;
DE   AltName: Full=G-protein coupled receptor 99;
DE   AltName: Full=P2Y purinoceptor 15;
DE            Short=P2Y15;
DE   AltName: Full=P2Y-like GPCR;
DE   AltName: Full=P2Y-like nucleotide receptor;
GN   Name=OXGR1; Synonyms=GPR80, GPR99, P2RY15, P2Y15;
DR   GuidetoPHARMACOLOGY; 162; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.
//
ID   OXER1_HUMAN             Reviewed;         423 AA.
AC   Q8TDS5; Q86WP7; Q8NGW4;
DE   RecName: Full=Oxoeicosanoid receptor 1;
DE   AltName: Full=5-oxo-ETE G-protein coupled receptor;
DE   AltName: Full=G-protein coupled receptor 170;
DE   AltName: Full=G-protein coupled receptor R527;
DE   AltName: Full=G-protein coupled receptor TG1019;
GN   Name=OXER1; Synonyms=GPR170, TG1019;
DR   GuidetoPHARMACOLOGY; 271; -.
DR   GO; GO:0050648; F:5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; NAS:UniProtKB.
DR   GO; GO:0050647; F:5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; NAS:UniProtKB.
DR   GO; GO:0050646; F:5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; NAS:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0030817; P:regulation of cAMP biosynthetic process; IDA:UniProtKB.
//
ID   OXLA_HUMAN              Reviewed;         567 AA.
AC   Q96RQ9; Q1WMJ3; Q4GZN1; Q4GZN2; Q6P2Q3; Q8TEM5; Q96RQ8;
DE   RecName: Full=L-amino-acid oxidase;
DE            Short=LAAO;
DE            Short=LAO;
DE            EC=1.4.3.2;
DE   AltName: Full=Interleukin-4-induced protein 1;
DE            Short=IL4-induced protein 1;
DE   AltName: Full=Protein Fig-1;
DE            Short=hFIG1;
DE   Flags: Precursor;
GN   Name=IL4I1; Synonyms=FIG1; ORFNames=UNQ636/PRO1265;
DR   GO; GO:0001716; F:L-amino-acid oxidase activity; EXP:Reactome.
//
ID   OXND1_HUMAN             Reviewed;         312 AA.
AC   Q96HP4; Q2HYC7; Q59FA4;
DE   RecName: Full=Oxidoreductase NAD-binding domain-containing protein 1;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=OXNAD1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   OXLD1_HUMAN             Reviewed;         147 AA.
AC   Q5BKU9; A6ND24;
DE   RecName: Full=Oxidoreductase-like domain-containing protein 1;
GN   Name=OXLD1; Synonyms=C17orf90;
//
ID   OXR1_HUMAN              Reviewed;         874 AA.
AC   Q8N573; A6NK11; A8KA34; B3KXL1; B7Z402; B7Z8N5; D3HIS6; Q3LIB5;
AC   Q6ZVK9; Q8N8V0; Q9H266; Q9NWC7;
DE   RecName: Full=Oxidation resistance protein 1;
GN   Name=OXR1; ORFNames=Nbla00307;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:Ensembl.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; IEA:InterPro.
DR   GO; GO:0071447; P:cellular response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; NAS:UniProtKB.
//
ID   OXSM_HUMAN              Reviewed;         459 AA.
AC   Q9NWU1;
DE   RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial;
DE            EC=2.3.1.41;
DE   AltName: Full=Beta-ketoacyl-ACP synthase;
DE   Flags: Precursor;
GN   Name=OXSM;
DR   GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IDA:HGNC.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IDA:HGNC.
DR   GO; GO:0051792; P:medium-chain fatty acid biosynthetic process; IDA:HGNC.
DR   GO; GO:0051790; P:short-chain fatty acid biosynthetic process; IDA:HGNC.
//
ID   OXSR1_HUMAN             Reviewed;         527 AA.
AC   O95747; Q3LR53; Q7Z501; Q9UPQ1;
DE   RecName: Full=Serine/threonine-protein kinase OSR1;
DE            EC=2.7.11.1;
DE   AltName: Full=Oxidative stress-responsive 1 protein;
GN   Name=OXSR1; Synonyms=KIAA1101, OSR1;
DR   GuidetoPHARMACOLOGY; 2132; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   OXYR_HUMAN              Reviewed;         389 AA.
AC   P30559; Q15071;
DE   RecName: Full=Oxytocin receptor;
DE            Short=OT-R;
GN   Name=OXTR;
DR   GuidetoPHARMACOLOGY; 369; -.
DR   GO; GO:0004990; F:oxytocin receptor activity; TAS:ProtInc.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0060206; P:estrous cycle phase; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; TAS:ProtInc.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0060137; P:maternal process involved in parturition; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0060455; P:negative regulation of gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010701; P:positive regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0060406; P:positive regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0070474; P:positive regulation of uterine smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0034059; P:response to anoxia; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0042713; P:sperm ejaculation; IEA:Ensembl.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
//
ID   OZF_HUMAN               Reviewed;         292 AA.
AC   Q15072; Q2TB94;
DE   RecName: Full=Zinc finger protein OZF;
DE   AltName: Full=Only zinc finger protein;
DE   AltName: Full=Zinc finger protein 146;
GN   Name=ZNF146; Synonyms=OZF;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   P121B_HUMAN             Reviewed;         834 AA.
AC   A6NF01;
DE   RecName: Full=Putative nuclear envelope pore membrane protein POM 121B;
GN   Name=POM121B;
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   P121C_HUMAN             Reviewed;        1229 AA.
AC   A8CG34; O75115; Q9Y2N3; Q9Y4S7;
DE   RecName: Full=Nuclear envelope pore membrane protein POM 121C;
DE   AltName: Full=Nuclear pore membrane protein 121-2;
DE            Short=POM121-2;
DE   AltName: Full=Pore membrane protein of 121 kDa C;
GN   Name=POM121C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   P121A_HUMAN             Reviewed;        1249 AA.
AC   Q96HA1; A6NFS9; A8CDT4; A8K933; A8MXF9; O75115; Q96DI0; Q9H9X1;
AC   Q9Y2N3; Q9Y4S7;
DE   RecName: Full=Nuclear envelope pore membrane protein POM 121;
DE   AltName: Full=Nuclear envelope pore membrane protein POM 121A;
DE   AltName: Full=Nucleoporin Nup121;
DE   AltName: Full=Pore membrane protein of 121 kDa;
GN   Name=POM121; Synonyms=KIAA0618, NUP121, POM121A;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   P12L1_HUMAN             Reviewed;         428 AA.
AC   Q3SYA9;
DE   RecName: Full=Putative POM121-like protein 1;
GN   Name=POM121L1P; Synonyms=POM121L1;
//
ID   P12L2_HUMAN             Reviewed;        1035 AA.
AC   Q96KW2; C9J1I7;
DE   RecName: Full=POM121-like protein 2;
GN   Name=POM121L2; Synonyms=POM121L;
//
ID   P12LL_HUMAN             Reviewed;         897 AA.
AC   A6NNC1; A6NNK7; Q8N834;
DE   RecName: Full=Putative POM121-like protein 1-like;
//
ID   P1L12_HUMAN             Reviewed;         296 AA.
AC   Q8N7R1; Q8NDI9;
DE   RecName: Full=POM121-like protein 12;
GN   Name=POM121L12;
//
ID   P20D1_HUMAN             Reviewed;         502 AA.
AC   Q6GTS8; Q6P4E3; Q96DM4;
DE   RecName: Full=Probable carboxypeptidase PM20D1;
DE            EC=3.4.17.-;
DE   AltName: Full=Peptidase M20 domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=PM20D1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:1901215; P:negative regulation of neuron death; IMP:UniProt.
DR   GO; GO:0050691; P:regulation of defense response to virus by host; IMP:UniProt.
DR   GO; GO:0050792; P:regulation of viral process; IMP:UniProt.
//
ID   P20D2_HUMAN             Reviewed;         436 AA.
AC   Q8IYS1; B4DYJ2; Q5T7J9; Q6MZV2; Q86XD9;
DE   RecName: Full=Peptidase M20 domain-containing protein 2;
DE   AltName: Full=Aminoacylase-1-like protein 2;
GN   Name=PM20D2; Synonyms=ACY1L2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
//
ID   P20L1_HUMAN             Reviewed;        1017 AA.
AC   A8MW92; A8MZC9; Q86U89; Q86W43; Q96BT0; Q9H702; Q9HBK3; Q9NYR3;
AC   Q9Y381;
DE   RecName: Full=PHD finger protein 20-like protein 1;
GN   Name=PHF20L1; ORFNames=CGI-72;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   P210L_HUMAN             Reviewed;        1888 AA.
AC   Q5VU65; E7EP56; Q5T4L7; Q6ZRN1; Q6ZRT4; Q6ZU81; Q8NDI6; Q9UF31;
DE   RecName: Full=Nuclear pore membrane glycoprotein 210-like;
DE   AltName: Full=Nucleoporin 210 kDa-like;
DE   AltName: Full=Nucleoporin Nup210-like;
DE   Flags: Precursor;
GN   Name=NUP210L;
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   P23D1_HUMAN             Reviewed;         279 AA.
AC   E9PI22;
DE   RecName: Full=Proline-rich protein 23D1;
GN   Name=PRR23D1;
//
ID   P23D2_HUMAN             Reviewed;         279 AA.
AC   P0DMB1;
DE   RecName: Full=Proline-rich protein 23D2;
GN   Name=PRR23D2;
//
ID   P2R3A_HUMAN             Reviewed;        1150 AA.
AC   Q06190; A8KAE7; B4DNU1; B7ZAE3; Q06189; Q9NPQ5;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha;
DE   AltName: Full=PP2A subunit B isoform PR72/PR130;
DE   AltName: Full=PP2A subunit B isoform R3 isoform;
DE   AltName: Full=PP2A subunit B isoforms B''-PR72/PR130;
DE   AltName: Full=PP2A subunit B isoforms B72/B130;
DE   AltName: Full=Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B;
GN   Name=PPP2R3A; Synonyms=PPP2R3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0001754; P:eye photoreceptor cell differentiation; IGI:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IGI:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0090249; P:regulation of cell motility involved in somitogenic axis elongation; IGI:BHF-UCL.
DR   GO; GO:0007525; P:somatic muscle development; IGI:BHF-UCL.
DR   GO; GO:0061053; P:somite development; ISS:BHF-UCL.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IC:BHF-UCL.
//
ID   P2R3B_HUMAN             Reviewed;         575 AA.
AC   Q9Y5P8; Q6P4G9; Q7RTT1; Q96H01;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta;
DE   AltName: Full=PP2A subunit B isoform PR48;
DE   AltName: Full=Protein phosphatase 2A 48 kDa regulatory subunit;
GN   Name=PPP2R3B; Synonyms=PPP2R3L;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
//
ID   P2R3C_HUMAN             Reviewed;         453 AA.
AC   Q969Q6; B4DEN7; D3DS97; D3DS98; Q5GJ55; Q5GJ56; Q6P4G2; Q86TZ3;
AC   Q9NWR9;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma;
DE   AltName: Full=Protein phosphatase subunit G5PR;
DE   AltName: Full=Rhabdomyosarcoma antigen MU-RMS-40.6A/6C;
GN   Name=PPP2R3C; Synonyms=C14orf10, G5PR;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0032147; P:activation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0002759; P:regulation of antimicrobial humoral response; IEA:Ensembl.
DR   GO; GO:0051900; P:regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
//
ID   P2RX1_HUMAN             Reviewed;         399 AA.
AC   P51575; Q9UK84;
DE   RecName: Full=P2X purinoceptor 1;
DE            Short=P2X1;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RX1; Synonyms=P2X1;
DR   GuidetoPHARMACOLOGY; 478; -.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0005262; F:calcium channel activity; TAS:Reactome.
DR   GO; GO:0005261; F:cation channel activity; IDA:MGI.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; IBA:RefGenome.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006812; P:cation transport; IBA:RefGenome.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007320; P:insemination; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; IDA:MGI.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0043270; P:positive regulation of ion transport; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; IDA:GOC.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0003056; P:regulation of vascular smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0002554; P:serotonin secretion by platelet; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0042310; P:vasoconstriction; IEA:Ensembl.
//
ID   P2RX2_HUMAN             Reviewed;         471 AA.
AC   Q9UBL9; A6NGB4; A6NH93; A6NHC2; A6NHU3; A6NIG9; Q6V9R6; Q9NR37;
AC   Q9NR38; Q9UHD5; Q9UHD6; Q9UHD7; Q9Y637; Q9Y638;
DE   RecName: Full=P2X purinoceptor 2;
DE            Short=P2X2;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RX2; Synonyms=P2X2;
DR   GuidetoPHARMACOLOGY; 479; -.
DR   GO; GO:0005524; F:ATP binding; NAS:BHF-UCL.
DR   GO; GO:0046870; F:cadmium ion binding; IEA:Ensembl.
DR   GO; GO:0050897; F:cobalt ion binding; IEA:Ensembl.
DR   GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0015276; F:ligand-gated ion channel activity; TAS:ProtInc.
DR   GO; GO:0045340; F:mercury ion binding; IEA:Ensembl.
DR   GO; GO:0016151; F:nickel cation binding; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; NAS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0003029; P:detection of hypoxic conditions in blood by carotid body chemoreceptor signaling; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; IEA:Ensembl.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; NAS:BHF-UCL.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:BHF-UCL.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; NAS:GOC.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0014832; P:urinary bladder smooth muscle contraction; IEA:Ensembl.
//
ID   P2RX3_HUMAN             Reviewed;         397 AA.
AC   P56373; Q6DK37; Q9UQB6;
DE   RecName: Full=P2X purinoceptor 3;
DE            Short=P2X3;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RX3;
DR   GuidetoPHARMACOLOGY; 480; -.
DR   GO; GO:0005524; F:ATP binding; NAS:BHF-UCL.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; NAS:BHF-UCL.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; NAS:BHF-UCL.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IEA:Ensembl.
DR   GO; GO:0030432; P:peristalsis; IEA:Ensembl.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; NAS:BHF-UCL.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; NAS:GOC.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0009743; P:response to carbohydrate; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0014832; P:urinary bladder smooth muscle contraction; IEA:Ensembl.
//
ID   P2RX4_HUMAN             Reviewed;         388 AA.
AC   Q99571; E7EPF7; F6RU17; O00450; O14722; Q5U089; Q5U090; Q8N4N1;
AC   Q9UBG9;
DE   RecName: Full=P2X purinoceptor 4;
DE            Short=P2X4;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RX4;
DR   GuidetoPHARMACOLOGY; 481; -.
DR   GO; GO:0005524; F:ATP binding; IC:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; IPI:BHF-UCL.
DR   GO; GO:0005507; F:copper ion binding; ISS:BHF-UCL.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:BHF-UCL.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; ISS:BHF-UCL.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0071318; P:cellular response to ATP; IDA:UniProtKB.
DR   GO; GO:0042118; P:endothelial cell activation; TAS:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0051899; P:membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; NAS:BHF-UCL.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:BHF-UCL.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0032308; P:positive regulation of prostaglandin secretion; NAS:BHF-UCL.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0002028; P:regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; IMP:BHF-UCL.
DR   GO; GO:0033198; P:response to ATP; IDA:BHF-UCL.
DR   GO; GO:0034405; P:response to fluid shear stress; IDA:BHF-UCL.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IDA:BHF-UCL.
DR   GO; GO:0001894; P:tissue homeostasis; NAS:BHF-UCL.
DR   GO; GO:0006810; P:transport; IDA:BHF-UCL.
//
ID   P2RX5_HUMAN             Reviewed;         422 AA.
AC   Q93086; G5E981; O43450; O75540; Q308M5; Q59F38; Q8IXW4; Q93087;
AC   Q9NZV0;
DE   RecName: Full=P2X purinoceptor 5;
DE            Short=P2X5;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RX5; Synonyms=P2X5;
DR   GuidetoPHARMACOLOGY; 482; -.
DR   GO; GO:0005524; F:ATP binding; NAS:BHF-UCL.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; NAS:BHF-UCL.
DR   GO; GO:0005216; F:ion channel activity; TAS:ProtInc.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; NAS:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; NAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; NAS:BHF-UCL.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   P2RX6_HUMAN             Reviewed;         441 AA.
AC   O15547; F6V3D7; Q32MB6; Q58F04; Q6IC33; Q9UL50;
DE   RecName: Full=P2X purinoceptor 6;
DE            Short=P2X6;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=P2XM;
DE   AltName: Full=Purinergic receptor;
DE   AltName: Full=Purinergic receptor P2X-like 1;
GN   Name=P2RX6; Synonyms=P2RXL1, P2X6;
DR   GuidetoPHARMACOLOGY; 483; -.
DR   GO; GO:0005524; F:ATP binding; NAS:BHF-UCL.
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; NAS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; NAS:BHF-UCL.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006812; P:cation transport; IBA:RefGenome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:BHF-UCL.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   P2RX7_HUMAN             Reviewed;         595 AA.
AC   Q99572; A8K2Z0; E7EMK6; F5H6P2; F5H7E8; F8W951; O14991; Q4VKH8;
AC   Q4VKH9; Q4VKI0; Q4VKI1; Q4VKI2; Q4VKI3; Q4VKI4; Q7Z771; Q96EV7;
DE   RecName: Full=P2X purinoceptor 7;
DE            Short=P2X7;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=P2Z receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RX7;
DR   GuidetoPHARMACOLOGY; 484; -.
DR   GO; GO:0005524; F:ATP binding; IC:BHF-UCL.
DR   GO; GO:0004931; F:extracellular ATP-gated cation channel activity; IDA:BHF-UCL.
DR   GO; GO:0001530; F:lipopolysaccharide binding; ISS:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:BHF-UCL.
DR   GO; GO:0001614; F:purinergic nucleotide receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0097190; P:apoptotic signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0032060; P:bleb assembly; ISS:BHF-UCL.
DR   GO; GO:0006812; P:cation transport; IDA:GOC.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0051899; P:membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0045779; P:negative regulation of bone resorption; ISS:BHF-UCL.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046931; P:pore complex assembly; IDA:BHF-UCL.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; ISS:BHF-UCL.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:BHF-UCL.
DR   GO; GO:0045919; P:positive regulation of cytolysis; ISS:BHF-UCL.
DR   GO; GO:0051495; P:positive regulation of cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:BHF-UCL.
DR   GO; GO:0035590; P:purinergic nucleotide receptor signaling pathway; IDA:GOC.
DR   GO; GO:0051709; P:regulation of killing of cells of other organism; NAS:BHF-UCL.
DR   GO; GO:0002028; P:regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0033198; P:response to ATP; IDA:BHF-UCL.
DR   GO; GO:0019233; P:sensory perception of pain; ISS:BHF-UCL.
//
ID   P2RY1_HUMAN             Reviewed;         373 AA.
AC   P47900;
DE   RecName: Full=P2Y purinoceptor 1;
DE            Short=P2Y1;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RY1;
DR   GuidetoPHARMACOLOGY; 323; -.
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0045032; F:ADP-activated nucleotide receptor activity; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0045031; F:ATP-activated nucleotide receptor activity; ISS:BHF-UCL.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0051100; P:negative regulation of binding; IEA:Ensembl.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043270; P:positive regulation of ion transport; IEA:Ensembl.
DR   GO; GO:0060406; P:positive regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0010469; P:regulation of receptor activity; IEA:Ensembl.
DR   GO; GO:0042312; P:regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0090075; P:relaxation of muscle; IEA:InterPro.
DR   GO; GO:0070848; P:response to growth factor; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; ISS:BHF-UCL.
//
ID   P2RY2_HUMAN             Reviewed;         377 AA.
AC   P41231; B2R9W3; Q96EM8;
DE   RecName: Full=P2Y purinoceptor 2;
DE            Short=P2Y2;
DE   AltName: Full=ATP receptor;
DE   AltName: Full=P2U purinoceptor 1;
DE            Short=P2U1;
DE   AltName: Full=P2U receptor 1;
DE   AltName: Full=Purinergic receptor;
GN   Name=P2RY2; Synonyms=P2RU1;
DR   GuidetoPHARMACOLOGY; 324; -.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006873; P:cellular ion homeostasis; TAS:ProtInc.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0070257; P:positive regulation of mucus secretion; IEA:Ensembl.
DR   GO; GO:0042312; P:regulation of vasodilation; IEA:InterPro.
//
ID   P2RY4_HUMAN             Reviewed;         365 AA.
AC   P51582; Q4VBB7; Q4VBB8; Q502W2; Q5JT22;
DE   RecName: Full=P2Y purinoceptor 4;
DE            Short=P2Y4;
DE   AltName: Full=P2P;
DE   AltName: Full=Uridine nucleotide receptor;
DE            Short=UNR;
GN   Name=P2RY4; Synonyms=NRU;
DR   GuidetoPHARMACOLOGY; 325; -.
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0015065; F:uridine nucleotide receptor activity; TAS:ProtInc.
DR   GO; GO:0045030; F:UTP-activated nucleotide receptor activity; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0030321; P:transepithelial chloride transport; IEA:Ensembl.
//
ID   P2RY6_HUMAN             Reviewed;         328 AA.
AC   Q15077; Q15754;
DE   RecName: Full=P2Y purinoceptor 6;
DE            Short=P2Y6;
GN   Name=P2RY6; ORFNames=PP2891;
DR   GuidetoPHARMACOLOGY; 326; -.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0045029; F:UDP-activated nucleotide receptor activity; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0030321; P:transepithelial chloride transport; IEA:Ensembl.
//
ID   P2RY8_HUMAN             Reviewed;         359 AA.
AC   Q86VZ1;
DE   RecName: Full=P2Y purinoceptor 8;
DE            Short=P2Y8;
GN   Name=P2RY8;
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
//
ID   P2Y10_HUMAN             Reviewed;         339 AA.
AC   O00398; D3DTE5; Q4VBN7; Q86V16;
DE   RecName: Full=Putative P2Y purinoceptor 10;
DE            Short=P2Y10;
DE   AltName: Full=P2Y-like receptor;
GN   Name=P2RY10;
DR   GuidetoPHARMACOLOGY; 165; -.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
//
ID   P2Y11_HUMAN             Reviewed;         374 AA.
AC   Q96G91; B2R8X9; O43190; Q9BYU4; Q9H170;
DE   RecName: Full=P2Y purinoceptor 11;
DE            Short=P2Y11;
GN   Name=P2RY11;
DR   GuidetoPHARMACOLOGY; 327; -.
DR   GO; GO:0045031; F:ATP-activated nucleotide receptor activity; IDA:BHF-UCL.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0030594; F:neurotransmitter receptor activity; IDA:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0001973; P:adenosine receptor signaling pathway; IDA:GOC.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0071318; P:cellular response to ATP; IDA:BHF-UCL.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0023041; P:neuronal signal transduction; IDA:BHF-UCL.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; IDA:GOC.
//
ID   P2Y12_HUMAN             Reviewed;         342 AA.
AC   Q9H244; D3DNJ5; Q546J7;
DE   RecName: Full=P2Y purinoceptor 12;
DE            Short=P2Y12;
DE   AltName: Full=ADP-glucose receptor;
DE            Short=ADPG-R;
DE   AltName: Full=P2T(AC);
DE   AltName: Full=P2Y(AC);
DE   AltName: Full=P2Y(cyc);
DE   AltName: Full=P2Y12 platelet ADP receptor;
DE            Short=P2Y(ADP);
DE   AltName: Full=SP1999;
GN   Name=P2RY12; Synonyms=HORK3;
DR   GuidetoPHARMACOLOGY; 328; -.
DR   GO; GO:0001621; F:ADP receptor activity; IEA:Ensembl.
DR   GO; GO:0001609; F:G-protein coupled adenosine receptor activity; IEA:Ensembl.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0030030; P:cell projection organization; IEA:Ensembl.
DR   GO; GO:0007599; P:hemostasis; NAS:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0010700; P:negative regulation of norepinephrine secretion; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0043270; P:positive regulation of ion transport; IEA:Ensembl.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
//
ID   P2Y14_HUMAN             Reviewed;         338 AA.
AC   Q15391; Q8IYT7;
DE   RecName: Full=P2Y purinoceptor 14;
DE            Short=P2Y14;
DE   AltName: Full=G-protein coupled receptor 105;
DE   AltName: Full=UDP-glucose receptor;
GN   Name=P2RY14; Synonyms=GPR105, KIAA0001;
DR   GuidetoPHARMACOLOGY; 330; -.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:InterPro.
DR   GO; GO:0045029; F:UDP-activated nucleotide receptor activity; NAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
//
ID   P2Y13_HUMAN             Reviewed;         354 AA.
AC   Q9BPV8; B2R827; Q05C50; Q6DKN4; Q8IUT5; Q8TDU7; Q9BY61;
DE   RecName: Full=P2Y purinoceptor 13;
DE            Short=P2Y13;
DE   AltName: Full=G-protein coupled receptor 86;
DE   AltName: Full=G-protein coupled receptor 94;
GN   Name=P2RY13; Synonyms=GPR86, GPR94; ORFNames=FKSG77;
DR   GuidetoPHARMACOLOGY; 329; -.
DR   GO; GO:0045028; F:G-protein coupled purinergic nucleotide receptor activity; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IEA:InterPro.
//
ID   P33MX_HUMAN             Reviewed;         305 AA.
AC   Q96A73; B2RD69; B8K1S6; Q6IA24; Q8NDU3; Q9BRE5; Q9H7D5; Q9ULM9;
DE   RecName: Full=Putative monooxygenase p33MONOX;
DE            EC=1.-.-.-;
DE   AltName: Full=Brain-derived rescue factor p60MONOX;
DE   AltName: Full=Flavin monooxygenase motif-containing protein of 33 kDa;
GN   Name=KIAA1191; Synonyms=P33MONOX;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   P3C2A_HUMAN             Reviewed;        1686 AA.
AC   O00443; B0LPH2; Q14CQ9;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha;
DE            Short=PI3K-C2-alpha;
DE            Short=PtdIns-3-kinase C2 subunit alpha;
DE            EC=2.7.1.154;
DE   AltName: Full=Phosphoinositide 3-kinase-C2-alpha;
GN   Name=PIK3C2A;
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IBA:RefGenome.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; TAS:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035004; F:phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0048268; P:clathrin coat assembly; TAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; TAS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0014829; P:vascular smooth muscle contraction; TAS:UniProtKB.
//
ID   P3C2G_HUMAN             Reviewed;        1445 AA.
AC   O75747; A1L3U0;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma;
DE            Short=PI3K-C2-gamma;
DE            Short=PtdIns-3-kinase C2 subunit gamma;
DE            EC=2.7.1.154;
DE   AltName: Full=Phosphoinositide 3-kinase-C2-gamma;
GN   Name=PIK3C2G;
DR   GuidetoPHARMACOLOGY; 2288; -.
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0016307; F:phosphatidylinositol phosphate kinase activity; NAS:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; NAS:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P3C2B_HUMAN             Reviewed;        1634 AA.
AC   O00750; O95666; Q5SW99;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta;
DE            Short=PI3K-C2-beta;
DE            Short=PtdIns-3-kinase C2 subunit beta;
DE            EC=2.7.1.154;
DE   AltName: Full=C2-PI3K;
DE   AltName: Full=Phosphoinositide 3-kinase-C2-beta;
GN   Name=PIK3C2B;
DR   GuidetoPHARMACOLOGY; 2151; -.
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IBA:RefGenome.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; NAS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0001727; F:lipid kinase activity; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; IBA:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P3H1_HUMAN              Reviewed;         736 AA.
AC   Q32P28; Q7KZR4; Q96BR8; Q96SK8; Q96SL5; Q96SN3; Q9H6K3; Q9HC86;
AC   Q9HC87;
DE   RecName: Full=Prolyl 3-hydroxylase 1;
DE            EC=1.14.11.7;
DE   AltName: Full=Growth suppressor 1;
DE   AltName: Full=Leucine- and proline-enriched proteoglycan 1;
DE            Short=Leprecan-1;
DE   Flags: Precursor;
GN   Name=LEPRE1; Synonyms=GROS1, P3H1; ORFNames=PSEC0109;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0019797; F:procollagen-proline 3-dioxygenase activity; ISS:UniProt.
DR   GO; GO:0032403; F:protein complex binding; ISS:UniProt.
DR   GO; GO:0060348; P:bone development; IMP:UniProt.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; ISS:UniProt.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0032963; P:collagen metabolic process; ISS:UniProt.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:1901874; P:negative regulation of post-translational protein modification; IMP:UniProt.
DR   GO; GO:0019511; P:peptidyl-proline hydroxylation; ISS:GOC.
DR   GO; GO:0006457; P:protein folding; IMP:UniProt.
DR   GO; GO:0018126; P:protein hydroxylation; IMP:UniProt.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
DR   GO; GO:0030278; P:regulation of ossification; IEA:Ensembl.
DR   GO; GO:0050708; P:regulation of protein secretion; IMP:UniProt.
//
ID   P3H2_HUMAN              Reviewed;         708 AA.
AC   Q8IVL5; B3KPK0; B3KWI9; D3DNV8; Q9NVI2;
DE   RecName: Full=Prolyl 3-hydroxylase 2;
DE            EC=1.14.11.7;
DE   AltName: Full=Leprecan-like protein 1;
DE   AltName: Full=Myxoid liposarcoma-associated protein 4;
DE   Flags: Precursor;
GN   Name=LEPREL1; Synonyms=MLAT4, P3H2;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0019797; F:procollagen-proline 3-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0032963; P:collagen metabolic process; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0019511; P:peptidyl-proline hydroxylation; IDA:UniProtKB.
//
ID   P3H3_HUMAN              Reviewed;         736 AA.
AC   Q8IVL6; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1;
DE   RecName: Full=Prolyl 3-hydroxylase 3;
DE            EC=1.14.11.7;
DE   AltName: Full=Leprecan-like protein 2;
DE   AltName: Full=Protein B;
DE   Flags: Precursor;
GN   Name=LEPREL2; Synonyms=P3H3;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0019797; F:procollagen-proline 3-dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
//
ID   P3IP1_HUMAN             Reviewed;         263 AA.
AC   Q96FE7; B4DRR9; D1MEI0; O00318; Q49A94; Q86YW2; Q8NCJ9;
DE   RecName: Full=Phosphoinositide-3-kinase-interacting protein 1;
DE   AltName: Full=Kringle domain-containing protein HGFL;
DE   Flags: Precursor;
GN   Name=PIK3IP1; Synonyms=HGFL;
DR   GO; GO:0036313; F:phosphatidylinositol 3-kinase catalytic subunit binding; IPI:UniProtKB.
DR   GO; GO:0043553; P:negative regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
//
ID   P3_HUMAN                Reviewed;         477 AA.
AC   P09131; Q5HY79; Q9BSL2;
DE   RecName: Full=P3 protein;
DE   AltName: Full=Solute carrier family 10 member 3;
GN   Name=SLC10A3; Synonyms=DXS253E, P3;
DR   GO; GO:0008508; F:bile acid:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   P4HA1_HUMAN             Reviewed;         534 AA.
AC   P13674; C9JL12; Q15082; Q15083; Q5VSQ5;
DE   RecName: Full=Prolyl 4-hydroxylase subunit alpha-1;
DE            Short=4-PH alpha-1;
DE            EC=1.14.11.2;
DE   AltName: Full=Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1;
DE   Flags: Precursor;
GN   Name=P4HA1; Synonyms=P4HA;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IEA:Ensembl.
//
ID   P4HA2_HUMAN             Reviewed;         535 AA.
AC   O15460; D3DQ85; D3DQ86; Q8WWN0;
DE   RecName: Full=Prolyl 4-hydroxylase subunit alpha-2;
DE            Short=4-PH alpha-2;
DE            EC=1.14.11.2;
DE   AltName: Full=Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2;
DE   Flags: Precursor;
GN   Name=P4HA2; ORFNames=UNQ290/PRO330;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; TAS:ProtInc.
DR   GO; GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IEA:Ensembl.
//
ID   P4HA3_HUMAN             Reviewed;         544 AA.
AC   Q7Z4N8; A0AV13; B4DUD3; Q5EBL3; Q5JPA9;
DE   RecName: Full=Prolyl 4-hydroxylase subunit alpha-3;
DE            Short=4-PH alpha-3;
DE            EC=1.14.11.2;
DE   AltName: Full=Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3;
DE   Flags: Precursor;
GN   Name=P4HA3; ORFNames=UNQ711/PRO1374;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR   GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; IEA:UniProtKB-EC.
//
ID   P4HTM_HUMAN             Reviewed;         502 AA.
AC   Q9NXG6; Q6PAG6; Q8TCJ9; Q8WV55; Q96F22; Q9BW77;
DE   RecName: Full=Transmembrane prolyl 4-hydroxylase;
DE            Short=P4H-TM;
DE            EC=1.14.11.-;
DE   AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 4;
DE            Short=HIF-PH4;
DE            Short=HIF-prolyl hydroxylase 4;
DE            Short=HPH-4;
GN   Name=P4HTM; Synonyms=PH4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.
//
ID   P4K2A_HUMAN             Reviewed;         479 AA.
AC   Q9BTU6; D3DR59; Q9NSG8;
DE   RecName: Full=Phosphatidylinositol 4-kinase type 2-alpha;
DE            EC=2.7.1.67;
DE   AltName: Full=Phosphatidylinositol 4-kinase type II-alpha;
GN   Name=PI4K2A;
DR   GuidetoPHARMACOLOGY; 2498; -.
DR   GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IDA:UniProtKB.
DR   GO; GO:0035651; F:AP-3 adaptor complex binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IDA:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P4K2B_HUMAN             Reviewed;         481 AA.
AC   Q8TCG2; Q9NUW2;
DE   RecName: Full=Phosphatidylinositol 4-kinase type 2-beta;
DE            EC=2.7.1.67;
DE   AltName: Full=Phosphatidylinositol 4-kinase type II-beta;
DE            Short=PI4KII-BETA;
GN   Name=PI4K2B;
DR   GuidetoPHARMACOLOGY; 2499; -.
DR   GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P4R3B_HUMAN             Reviewed;         849 AA.
AC   Q5MIZ7; Q6P9B0; Q86XB8; Q9BQJ0; Q9BRK2; Q9H913; Q9P2G0;
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 3B;
DE   AltName: Full=SMEK homolog 2;
GN   Name=SMEK2; Synonyms=KIAA1387, PP4R3B, PPP4R3B;
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
//
ID   P4R3A_HUMAN             Reviewed;         833 AA.
AC   Q6IN85; Q69YK6; Q86U23; Q86YI7; Q8IVG1; Q9H3F1; Q9H7U8; Q9NV01;
AC   Q9NWP1;
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 3A;
DE   AltName: Full=SMEK homolog 1;
GN   Name=SMEK1; Synonyms=KIAA2010, PP4R3A, PPP4R3A; ORFNames=MSTP033;
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
//
ID   P52K_HUMAN              Reviewed;         761 AA.
AC   O43422; A8K728; Q17RY9; Q8WTW1; Q9Y3Z4;
DE   RecName: Full=52 kDa repressor of the inhibitor of the protein kinase;
DE            Short=p52rIPK;
DE   AltName: Full=58 kDa interferon-induced protein kinase-interacting protein;
DE            Short=p58IPK-interacting protein;
DE   AltName: Full=Death-associated protein 4;
DE   AltName: Full=THAP domain-containing protein 0;
GN   Name=PRKRIR; Synonyms=DAP4, P52RIPK, THAP0;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   P53_HUMAN               Reviewed;         393 AA.
AC   P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809;
AC   Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4;
AC   Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2;
AC   Q9NZD0; Q9UBI2; Q9UQ61;
DE   RecName: Full=Cellular tumor antigen p53;
DE   AltName: Full=Antigen NY-CO-13;
DE   AltName: Full=Phosphoprotein p53;
DE   AltName: Full=Tumor suppressor p53;
GN   Name=TP53; Synonyms=P53;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0035033; F:histone deacetylase regulator activity; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002039; F:p53 binding; IBA:RefGenome.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProt.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0002326; P:B cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0006284; P:base-excision repair; TAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007569; P:cell aging; IMP:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IEP:UniProtKB.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.
DR   GO; GO:0034644; P:cellular response to UV; IBA:RefGenome.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0031497; P:chromatin assembly; IDA:UniProtKB.
DR   GO; GO:0008340; P:determination of adult lifespan; ISS:BHF-UCL.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:BHF-UCL.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0006983; P:ER overload response; IDA:MGI.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:HGNC.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IMP:BHF-UCL.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IMP:UniProtKB.
DR   GO; GO:0051097; P:negative regulation of helicase activity; TAS:UniProtKB.
DR   GO; GO:1901525; P:negative regulation of macromitophagy; IEA:Ensembl.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0097252; P:oligodendrocyte apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090403; P:oxidative stress-induced premature senescence; IMP:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0090343; P:positive regulation of cell aging; IEA:Ensembl.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IBA:RefGenome.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IBA:RefGenome.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0070245; P:positive regulation of thymocyte apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; TAS:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; TAS:UniProtKB.
DR   GO; GO:1902108; P:regulation of mitochondrial membrane permeability involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0034103; P:regulation of tissue remodeling; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0090399; P:replicative senescence; IMP:BHF-UCL.
DR   GO; GO:0046677; P:response to antibiotic; IEP:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IMP:BHF-UCL.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IBA:RefGenome.
DR   GO; GO:0009303; P:rRNA transcription; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0002360; P:T cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0002309; P:T cell proliferation involved in immune response; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   P55G_HUMAN              Reviewed;         461 AA.
AC   Q92569; B2R9C1; D3DQ12; O60482; Q5T4P1; Q5T4P2;
DE   RecName: Full=Phosphatidylinositol 3-kinase regulatory subunit gamma;
DE            Short=PI3-kinase regulatory subunit gamma;
DE            Short=PI3K regulatory subunit gamma;
DE            Short=PtdIns-3-kinase regulatory subunit gamma;
DE   AltName: Full=Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma;
DE            Short=PI3-kinase subunit p55-gamma;
DE            Short=PtdIns-3-kinase regulatory subunit p55-gamma;
DE   AltName: Full=p55PIK;
GN   Name=PIK3R3;
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:ProtInc.
DR   GO; GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; TAS:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P5CR1_HUMAN             Reviewed;         319 AA.
AC   P32322; A6NFM2; B4DMU0; Q6FHI4; Q96DI6; Q9HBQ4;
DE   RecName: Full=Pyrroline-5-carboxylate reductase 1, mitochondrial;
DE            Short=P5C reductase 1;
DE            Short=P5CR 1;
DE            EC=1.5.1.2;
GN   Name=PYCR1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006561; P:proline biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P5CR2_HUMAN             Reviewed;         320 AA.
AC   Q96C36; A8K798; Q7Z515; Q9Y5J4;
DE   RecName: Full=Pyrroline-5-carboxylate reductase 2;
DE            Short=P5C reductase 2;
DE            Short=P5CR 2;
DE            EC=1.5.1.2;
GN   Name=PYCR2;
DR   GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   P5CR3_HUMAN             Reviewed;         274 AA.
AC   Q53H96; B3KMB5; Q8N3N9; Q96HX4; Q9H896;
DE   RecName: Full=Pyrroline-5-carboxylate reductase 3;
DE            Short=P5C reductase 3;
DE            Short=P5CR 3;
DE            EC=1.5.1.2;
DE   AltName: Full=Pyrroline-5-carboxylate reductase-like protein;
GN   Name=PYCRL;
DR   GO; GO:0004735; F:pyrroline-5-carboxylate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   P5CS_HUMAN              Reviewed;         795 AA.
AC   P54886; B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; O95952; Q3KQU2;
AC   Q5T566; Q5T567; Q9UM72;
DE   RecName: Full=Delta-1-pyrroline-5-carboxylate synthase;
DE            Short=P5CS;
DE   AltName: Full=Aldehyde dehydrogenase family 18 member A1;
DE   Includes:
DE     RecName: Full=Glutamate 5-kinase;
DE              Short=GK;
DE              EC=2.7.2.11;
DE     AltName: Full=Gamma-glutamyl kinase;
DE   Includes:
DE     RecName: Full=Gamma-glutamyl phosphate reductase;
DE              Short=GPR;
DE              EC=1.2.1.41;
DE     AltName: Full=Glutamate-5-semialdehyde dehydrogenase;
DE     AltName: Full=Glutamyl-gamma-semialdehyde dehydrogenase;
GN   Name=ALDH18A1; Synonyms=GSAS, P5CS, PYCS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004349; F:glutamate 5-kinase activity; IDA:UniProtKB.
DR   GO; GO:0004350; F:glutamate-5-semialdehyde dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019240; P:citrulline biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006536; P:glutamate metabolic process; IMP:UniProtKB.
DR   GO; GO:0055129; P:L-proline biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006592; P:ornithine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006561; P:proline biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   P5F1B_HUMAN             Reviewed;         359 AA.
AC   Q06416; D5K9V4; Q2VIK6; Q9BZV7; Q9BZV9;
DE   RecName: Full=Putative POU domain, class 5, transcription factor 1B;
DE   AltName: Full=Octamer-binding protein 3-like;
DE   AltName: Full=Octamer-binding transcription factor 3-like;
GN   Name=POU5F1B; Synonyms=OTF3C, OTF3P1, POU5F1P1, POU5FLC20, POU5FLC8;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   P5I11_HUMAN             Reviewed;         189 AA.
AC   O14683; Q3ZCS0;
DE   RecName: Full=Tumor protein p53-inducible protein 11;
DE   AltName: Full=p53-induced gene 11 protein;
GN   Name=TP53I11; Synonyms=PIG11;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   P5I13_HUMAN             Reviewed;         393 AA.
AC   Q8NBR0; Q7L5U3;
DE   RecName: Full=Tumor protein p53-inducible protein 13;
DE   AltName: Full=Damage-stimulated cytoplasmic protein 1;
DE   Flags: Precursor;
GN   Name=TP53I13; Synonyms=DSCP1;
//
ID   P63_HUMAN               Reviewed;         680 AA.
AC   Q9H3D4; O75080; O75195; O75922; O76078; Q6VEG2; Q6VEG3; Q6VEG4;
AC   Q6VFJ1; Q6VFJ2; Q6VFJ3; Q6VH20; Q7LDI3; Q7LDI4; Q7LDI5; Q96KR0;
AC   Q9H3D2; Q9H3D3; Q9H3P8; Q9NPH7; Q9P1B4; Q9P1B5; Q9P1B6; Q9P1B7;
AC   Q9UBV9; Q9UE10; Q9UP26; Q9UP27; Q9UP28; Q9UP74;
DE   RecName: Full=Tumor protein 63;
DE            Short=p63;
DE   AltName: Full=Chronic ulcerative stomatitis protein;
DE            Short=CUSP;
DE   AltName: Full=Keratinocyte transcription factor KET;
DE   AltName: Full=Transformation-related protein 63;
DE            Short=TP63;
DE   AltName: Full=Tumor protein p73-like;
DE            Short=p73L;
DE   AltName: Full=p40;
DE   AltName: Full=p51;
GN   Name=TP63; Synonyms=KET, P63, P73H, P73L, TP73L;
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0003684; F:damaged DNA binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002039; F:p53 binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IBA:RefGenome.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0060197; P:cloacal septation; IEA:Ensembl.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IBA:RefGenome.
DR   GO; GO:0007499; P:ectoderm and mesoderm interaction; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0010481; P:epidermal cell division; IEA:Ensembl.
DR   GO; GO:0002064; P:epithelial cell development; IEA:Ensembl.
DR   GO; GO:0001736; P:establishment of planar polarity; IEA:Ensembl.
DR   GO; GO:0048807; P:female genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IBA:RefGenome.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IBA:RefGenome.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:2000381; P:negative regulation of mesoderm development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0030859; P:polarized epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; IDA:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0060513; P:prostatic bud formation; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IBA:RefGenome.
DR   GO; GO:0010332; P:response to gamma radiation; IBA:RefGenome.
DR   GO; GO:0010165; P:response to X-ray; IBA:RefGenome.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR   GO; GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; IEA:Ensembl.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Ensembl.
DR   GO; GO:0060157; P:urinary bladder development; IEA:Ensembl.
//
ID   P66A_HUMAN              Reviewed;         633 AA.
AC   Q86YP4; B5MC40; Q7L3J2; Q96F28; Q9NPU2; Q9NXS1;
DE   RecName: Full=Transcriptional repressor p66-alpha;
DE            Short=Hp66alpha;
DE   AltName: Full=GATA zinc finger domain-containing protein 2A;
GN   Name=GATAD2A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0021506; P:anterior neuropore closure; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0006306; P:DNA methylation; TAS:UniProtKB.
DR   GO; GO:0010172; P:embryonic body morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001842; P:neural fold formation; IEA:Ensembl.
DR   GO; GO:0012501; P:programmed cell death; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   P66B_HUMAN              Reviewed;         593 AA.
AC   Q8WXI9; D3DUZ2; Q5VUR2; Q7LG68; Q9ULS0;
DE   RecName: Full=Transcriptional repressor p66-beta;
DE   AltName: Full=GATA zinc finger domain-containing protein 2B;
DE   AltName: Full=p66/p68;
GN   Name=GATAD2B; Synonyms=KIAA1150;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   P73_HUMAN               Reviewed;         636 AA.
AC   O15350; B7Z7J4; B7Z8Z1; B7Z9C1; C9J521; O15351; Q17RN8; Q5TBV5;
AC   Q5TBV6; Q8NHW9; Q8TDY5; Q8TDY6; Q9NTK8;
DE   RecName: Full=Tumor protein p73;
DE   AltName: Full=p53-like transcription factor;
DE   AltName: Full=p53-related protein;
GN   Name=TP73; Synonyms=P73;
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0003684; F:damaged DNA binding; IBA:RefGenome.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002039; F:p53 binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IBA:RefGenome.
DR   GO; GO:0033326; P:cerebrospinal fluid secretion; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IBA:RefGenome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; TAS:ProtInc.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0006298; P:mismatch repair; TAS:ProtInc.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IBA:RefGenome.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IBA:RefGenome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IBA:RefGenome.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045793; P:positive regulation of cell size; IEA:Ensembl.
DR   GO; GO:1902167; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IBA:RefGenome.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   P85A_HUMAN              Reviewed;         724 AA.
AC   P27986; B3KT19; D3DWA0; E7EX19; Q15747; Q4VBZ7; Q53EM6; Q8IXA2;
AC   Q8N1C5;
DE   RecName: Full=Phosphatidylinositol 3-kinase regulatory subunit alpha;
DE            Short=PI3-kinase regulatory subunit alpha;
DE            Short=PI3K regulatory subunit alpha;
DE            Short=PtdIns-3-kinase regulatory subunit alpha;
DE   AltName: Full=Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;
DE            Short=PI3-kinase subunit p85-alpha;
DE            Short=PtdIns-3-kinase regulatory subunit p85-alpha;
GN   Name=PIK3R1; Synonyms=GRB1;
DR   GO; GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.
DR   GO; GO:0043559; F:insulin binding; IDA:UniProtKB.
DR   GO; GO:0005158; F:insulin receptor binding; IPI:UniProtKB.
DR   GO; GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:BHF-UCL.
DR   GO; GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; ISS:BHF-UCL.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051531; P:NFAT protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   P85B_HUMAN              Reviewed;         728 AA.
AC   O00459; Q5EAT5; Q9UPH9;
DE   RecName: Full=Phosphatidylinositol 3-kinase regulatory subunit beta;
DE            Short=PI3-kinase regulatory subunit beta;
DE            Short=PI3K regulatory subunit beta;
DE            Short=PtdIns-3-kinase regulatory subunit beta;
DE   AltName: Full=Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta;
DE            Short=PI3-kinase subunit p85-beta;
DE            Short=PtdIns-3-kinase regulatory subunit p85-beta;
GN   Name=PIK3R2;
DR   GO; GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; ISS:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   PA1B2_HUMAN             Reviewed;         229 AA.
AC   P68402; A8DPS5; A8DPS6; A8DPS7; E9PEJ5; E9PLP3; O00687; Q29459;
AC   Q6IBR6;
DE   RecName: Full=Platelet-activating factor acetylhydrolase IB subunit beta;
DE            EC=3.1.1.47;
DE   AltName: Full=PAF acetylhydrolase 30 kDa subunit;
DE            Short=PAF-AH 30 kDa subunit;
DE   AltName: Full=PAF-AH subunit beta;
DE            Short=PAFAH subunit beta;
GN   Name=PAFAH1B2; Synonyms=PAFAHB;
DR   GO; GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PA1B3_HUMAN             Reviewed;         231 AA.
AC   Q15102; Q53X88;
DE   RecName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma;
DE            EC=3.1.1.47;
DE   AltName: Full=PAF acetylhydrolase 29 kDa subunit;
DE            Short=PAF-AH 29 kDa subunit;
DE   AltName: Full=PAF-AH subunit gamma;
DE            Short=PAFAH subunit gamma;
GN   Name=PAFAH1B3; Synonyms=PAFAHG;
DR   GO; GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PA21B_HUMAN             Reviewed;         148 AA.
AC   P04054; B2R4H5; Q3KPI1;
DE   RecName: Full=Phospholipase A2;
DE            EC=3.1.1.4;
DE   AltName: Full=Group IB phospholipase A2;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 1B;
DE   Flags: Precursor;
GN   Name=PLA2G1B; Synonyms=PLA2, PLA2A, PPLA2;
DR   GO; GO:0032052; F:bile acid binding; ISS:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; IDA:BHF-UCL.
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.
DR   GO; GO:0032431; P:activation of phospholipase A2 activity; TAS:BHF-UCL.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0050482; P:arachidonic acid secretion; TAS:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0015758; P:glucose transport; ISS:BHF-UCL.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0032637; P:interleukin-8 production; ISS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:BHF-UCL.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0044240; P:multicellular organismal lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0002446; P:neutrophil mediated immunity; ISS:BHF-UCL.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IDA:BHF-UCL.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; ISS:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IC:BHF-UCL.
DR   GO; GO:0050778; P:positive regulation of immune response; ISS:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; TAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA24A_HUMAN             Reviewed;         749 AA.
AC   P47712; B1AKG4; Q29R80;
DE   RecName: Full=Cytosolic phospholipase A2;
DE            Short=cPLA2;
DE   AltName: Full=Phospholipase A2 group IVA;
DE   Includes:
DE     RecName: Full=Phospholipase A2;
DE              EC=3.1.1.4;
DE     AltName: Full=Phosphatidylcholine 2-acylhydrolase;
DE   Includes:
DE     RecName: Full=Lysophospholipase;
DE              EC=3.1.1.5;
GN   Name=PLA2G4A; Synonyms=CPLA2, PLA2G4;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; EXP:Reactome.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0046456; P:icosanoid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006690; P:icosanoid metabolic process; NAS:UniProtKB.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006663; P:platelet activating factor biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA24B_HUMAN             Reviewed;         781 AA.
AC   P0C869; B4DRT9; O95712; Q19KD5; Q19KD6; Q59GF9; Q8TB10; Q9UKV7;
DE   RecName: Full=Cytosolic phospholipase A2 beta;
DE            Short=cPLA2-beta;
DE            EC=3.1.1.4;
DE   AltName: Full=Phospholipase A2 group IVB;
GN   Name=PLA2G4B;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; NAS:UniProtKB.
DR   GO; GO:0004622; F:lysophospholipase activity; NAS:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; NAS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0046475; P:glycerophospholipid catabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0007567; P:parturition; NAS:UniProtKB.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA24C_HUMAN             Reviewed;         541 AA.
AC   Q9UP65; B2RB71; B4DI40; O75457; Q6IBI8; Q9UG68;
DE   RecName: Full=Cytosolic phospholipase A2 gamma;
DE            Short=cPLA2-gamma;
DE            EC=3.1.1.4;
DE   AltName: Full=Phospholipase A2 group IVC;
DE   Flags: Precursor;
GN   Name=PLA2G4C;
DR   GO; GO:0047499; F:calcium-independent phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; NAS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; NAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0046475; P:glycerophospholipid catabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0007567; P:parturition; NAS:UniProtKB.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA24D_HUMAN             Reviewed;         818 AA.
AC   Q86XP0; Q8N176;
DE   RecName: Full=Cytosolic phospholipase A2 delta;
DE            Short=cPLA2-delta;
DE            EC=3.1.1.4;
DE   AltName: Full=Phospholipase A2 group IVD;
GN   Name=PLA2G4D;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA24E_HUMAN             Reviewed;         856 AA.
AC   Q3MJ16; Q6ZSC0;
DE   RecName: Full=Cytosolic phospholipase A2 epsilon;
DE            Short=cPLA2-epsilon;
DE            EC=3.1.1.4;
DE   AltName: Full=Phospholipase A2 group IVE;
GN   Name=PLA2G4E;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA24F_HUMAN             Reviewed;         849 AA.
AC   Q68DD2; Q6ZMC8;
DE   RecName: Full=Cytosolic phospholipase A2 zeta;
DE            Short=cPLA2-zeta;
DE            EC=3.1.1.4;
DE   AltName: Full=Phospholipase A2 group IVF;
GN   Name=PLA2G4F;
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; IEA:Ensembl.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2G3_HUMAN             Reviewed;         509 AA.
AC   Q9NZ20; O95768;
DE   RecName: Full=Group 3 secretory phospholipase A2;
DE            EC=3.1.1.4;
DE   AltName: Full=Group III secretory phospholipase A2;
DE            Short=GIII sPLA2;
DE            Short=sPLA2-III;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 3;
DE   Flags: Precursor;
GN   Name=PLA2G3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; TAS:ProtInc.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2G4_HUMAN             Reviewed;         394 AA.
AC   Q9UQ80; O43846; Q9UM59;
DE   RecName: Full=Proliferation-associated protein 2G4;
DE   AltName: Full=Cell cycle protein p38-2G4 homolog;
DE            Short=hG4-1;
DE   AltName: Full=ErbB3-binding protein 1;
GN   Name=PA2G4; Synonyms=EBP1;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PA2G5_HUMAN             Reviewed;         138 AA.
AC   P39877; Q8N435;
DE   RecName: Full=Calcium-dependent phospholipase A2;
DE            EC=3.1.1.4;
DE   AltName: Full=Group V phospholipase A2;
DE   AltName: Full=PLA2-10;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 5;
DE   Flags: Precursor;
GN   Name=PLA2G5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006663; P:platelet activating factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2GA_HUMAN             Reviewed;         144 AA.
AC   P14555; A8K5I7; Q6DN24; Q6IBD9; Q9UCD2;
DE   RecName: Full=Phospholipase A2, membrane associated;
DE            EC=3.1.1.4;
DE   AltName: Full=GIIC sPLA2;
DE   AltName: Full=Group IIA phospholipase A2;
DE   AltName: Full=Non-pancreatic secretory phospholipase A2;
DE            Short=NPS-PLA2;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 2A;
DE   Flags: Precursor;
GN   Name=PLA2G2A; Synonyms=PLA2B, PLA2L, RASF-A;
DR   GuidetoPHARMACOLOGY; 1417; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; TAS:UniProtKB.
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; TAS:BHF-UCL.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; TAS:BHF-UCL.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0046473; P:phosphatidic acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2GC_HUMAN             Reviewed;         149 AA.
AC   Q5R387; Q7M4M6;
DE   RecName: Full=Putative inactive group IIC secretory phospholipase A2;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase-like protein GIIC;
DE   Flags: Precursor;
GN   Name=PLA2G2C;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
//
ID   PA2GF_HUMAN             Reviewed;         168 AA.
AC   Q9BZM2; Q5R385; Q8N217; Q9H506;
DE   RecName: Full=Group IIF secretory phospholipase A2;
DE            Short=GIIF sPLA2;
DE            Short=sPLA2-IIF;
DE            EC=3.1.1.4;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 2F;
DE   Flags: Precursor;
GN   Name=PLA2G2F;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; NAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2GE_HUMAN             Reviewed;         142 AA.
AC   Q9NZK7; Q5VXJ8;
DE   RecName: Full=Group IIE secretory phospholipase A2;
DE            Short=GIIE sPLA2;
DE            Short=sPLA2-IIE;
DE            EC=3.1.1.4;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 2E;
DE   Flags: Precursor;
GN   Name=PLA2G2E;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; TAS:ProtInc.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2GD_HUMAN             Reviewed;         145 AA.
AC   Q9UNK4; A8K2Z1; B1AEL9; Q9UK01;
DE   RecName: Full=Group IID secretory phospholipase A2;
DE            Short=GIID sPLA2;
DE            Short=sPLA2-IID;
DE            EC=3.1.1.4;
DE   AltName: Full=PLA2IID;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 2D;
DE   AltName: Full=Secretory-type PLA, stroma-associated homolog;
DE   Flags: Precursor;
GN   Name=PLA2G2D; Synonyms=SPLASH;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; TAS:ProtInc.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PA2GX_HUMAN             Reviewed;         165 AA.
AC   O15496; Q14DU3; Q6NT23;
DE   RecName: Full=Group 10 secretory phospholipase A2;
DE            EC=3.1.1.4;
DE   AltName: Full=Group X secretory phospholipase A2;
DE            Short=GX sPLA2;
DE            Short=sPLA2-X;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 10;
DE   Flags: Precursor;
GN   Name=PLA2G10;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; TAS:ProtInc.
DR   GO; GO:0004620; F:phospholipase activity; ISS:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; NAS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IDA:MGI.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0051977; P:lysophospholipid transport; IDA:MGI.
DR   GO; GO:0090370; P:negative regulation of cholesterol efflux; ISS:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0090238; P:positive regulation of arachidonic acid secretion; ISS:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IMP:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0032308; P:positive regulation of prostaglandin secretion; IMP:BHF-UCL.
DR   GO; GO:0043030; P:regulation of macrophage activation; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PAAF1_HUMAN             Reviewed;         392 AA.
AC   Q9BRP4; A6NDR5; B4DPB0; B7ZAS9; Q4G165; Q53HS9; Q7Z500; Q8TBU6;
AC   Q9HAB6;
DE   RecName: Full=Proteasomal ATPase-associated factor 1;
DE   AltName: Full=Protein G-16;
DE   AltName: Full=WD repeat-containing protein 71;
GN   Name=PAAF1; Synonyms=WDR71;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PAB4L_HUMAN             Reviewed;         370 AA.
AC   P0CB38;
DE   RecName: Full=Polyadenylate-binding protein 4-like;
DE            Short=PABP-4-like;
DE            Short=Poly(A)-binding protein 4-like;
GN   Name=PABPC4L;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   PABP1_HUMAN             Reviewed;         636 AA.
AC   P11940; Q15097; Q93004;
DE   RecName: Full=Polyadenylate-binding protein 1;
DE            Short=PABP-1;
DE            Short=Poly(A)-binding protein 1;
GN   Name=PABPC1; Synonyms=PAB1, PABP1, PABPC2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008494; F:translation activator activity; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006378; P:mRNA polyadenylation; TAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0048255; P:mRNA stabilization; TAS:UniProtKB.
DR   GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; TAS:GOC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
//
ID   PABP2_HUMAN             Reviewed;         306 AA.
AC   Q86U42; D3DS49; O43484;
DE   RecName: Full=Polyadenylate-binding protein 2;
DE            Short=PABP-2;
DE            Short=Poly(A)-binding protein 2;
DE   AltName: Full=Nuclear poly(A)-binding protein 1;
DE   AltName: Full=Poly(A)-binding protein II;
DE            Short=PABII;
DE   AltName: Full=Polyadenylate-binding nuclear protein 1;
GN   Name=PABPN1; Synonyms=PAB2, PABP2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0046778; P:modification by virus of host mRNA processing; TAS:Reactome.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:Reactome.
DR   GO; GO:0019054; P:modulation by virus of host process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
//
ID   PABP3_HUMAN             Reviewed;         631 AA.
AC   Q9H361; Q8NHV0; Q9H086;
DE   RecName: Full=Polyadenylate-binding protein 3;
DE            Short=PABP-3;
DE            Short=Poly(A)-binding protein 3;
DE   AltName: Full=Testis-specific poly(A)-binding protein;
GN   Name=PABPC3; Synonyms=PABP3, PABPL3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; NAS:UniProtKB.
//
ID   PABP5_HUMAN             Reviewed;         382 AA.
AC   Q96DU9; A8K240; Q5JQF4; Q6P529; Q9UFE5;
DE   RecName: Full=Polyadenylate-binding protein 5;
DE            Short=PABP-5;
DE            Short=Poly(A)-binding protein 5;
GN   Name=PABPC5; Synonyms=PABP5;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   PABP4_HUMAN             Reviewed;         644 AA.
AC   Q13310; B1ANQ8; Q4VC03; Q6P0N3;
DE   RecName: Full=Polyadenylate-binding protein 4;
DE            Short=PABP-4;
DE            Short=Poly(A)-binding protein 4;
DE   AltName: Full=Activated-platelet protein 1;
DE            Short=APP-1;
DE   AltName: Full=Inducible poly(A)-binding protein;
DE            Short=iPABP;
GN   Name=PABPC4; Synonyms=APP1, PABP4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   PACA_HUMAN              Reviewed;         176 AA.
AC   P18509; B2R7N4; Q52LQ0;
DE   RecName: Full=Pituitary adenylate cyclase-activating polypeptide;
DE            Short=PACAP;
DE   Contains:
DE     RecName: Full=PACAP-related peptide;
DE     AltName: Full=PRP-48;
DE   Contains:
DE     RecName: Full=Pituitary adenylate cyclase-activating polypeptide 27;
DE              Short=PACAP-27;
DE              Short=PACAP27;
DE   Contains:
DE     RecName: Full=Pituitary adenylate cyclase-activating polypeptide 38;
DE              Short=PACAP-38;
DE              Short=PACAP38;
DE   Flags: Precursor;
GN   Name=ADCYAP1;
DR   GO; GO:0005184; F:neuropeptide hormone activity; IDA:UniProtKB.
DR   GO; GO:0051428; F:peptide hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0016521; F:pituitary adenylate cyclase activating polypeptide activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:Reactome.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0001821; P:histamine secretion; IEA:Ensembl.
DR   GO; GO:0002865; P:negative regulation of acute inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0002878; P:negative regulation of acute inflammatory response to non-antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0060253; P:negative regulation of glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010656; P:negative regulation of muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0034259; P:negative regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; IDA:UniProtKB.
DR   GO; GO:0090274; P:positive regulation of somatostatin secretion; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070445; P:regulation of oligodendrocyte progenitor proliferation; IEA:Ensembl.
DR   GO; GO:0060078; P:regulation of postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:Reactome.
//
ID   PACE1_HUMAN             Reviewed;         742 AA.
AC   Q8IZE3; A8K8Z2; Q5THA6; Q5THA8; Q8IZN9; Q96C56; Q9UBK6;
DE   RecName: Full=Protein-associating with the carboxyl-terminal domain of ezrin;
DE   AltName: Full=Ezrin-binding protein PACE-1;
DE   AltName: Full=SCY1-like protein 3;
GN   Name=SCYL3; Synonyms=PACE1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
//
ID   PACN1_HUMAN             Reviewed;         444 AA.
AC   Q9BY11; Q9P2G8;
DE   RecName: Full=Protein kinase C and casein kinase substrate in neurons protein 1;
DE   AltName: Full=Syndapin-1;
GN   Name=PACSIN1; Synonyms=KIAA1379;
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0097320; P:membrane tubulation; IDA:UniProtKB.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:1900006; P:positive regulation of dendrite development; ISS:BHF-UCL.
DR   GO; GO:0072657; P:protein localization to membrane; ISS:UniProtKB.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
//
ID   PACN2_HUMAN             Reviewed;         486 AA.
AC   Q9UNF0; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9Y4V2;
DE   RecName: Full=Protein kinase C and casein kinase substrate in neurons protein 2;
DE   AltName: Full=Syndapin-2;
DE   AltName: Full=Syndapin-II;
GN   Name=PACSIN2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0070836; P:caveola assembly; IMP:UniProtKB.
DR   GO; GO:0072584; P:caveolin-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0048858; P:cell projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0097320; P:membrane tubulation; IDA:UniProtKB.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0036010; P:protein localization to endosome; IMP:UniProtKB.
//
ID   PACN3_HUMAN             Reviewed;         424 AA.
AC   Q9UKS6; A6NH84; Q9H331; Q9NWV9;
DE   RecName: Full=Protein kinase C and casein kinase substrate in neurons protein 3;
DE   AltName: Full=SH3 domain-containing protein 6511;
GN   Name=PACSIN3;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0008092; F:cytoskeletal protein binding; ISS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0097320; P:membrane tubulation; IDA:UniProtKB.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0045806; P:negative regulation of endocytosis; ISS:UniProtKB.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.
//
ID   PACRG_HUMAN             Reviewed;         296 AA.
AC   Q96M98; E1P5B5; Q6IMB8; Q8IZM1; Q8NHP5; Q9H1V9;
DE   RecName: Full=Parkin coregulated gene protein;
DE   AltName: Full=Molecular chaperone/chaperonin-binding protein;
DE   AltName: Full=PARK2 coregulated gene protein;
GN   Name=PACRG; Synonyms=GLUP;
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   PACR_HUMAN              Reviewed;         468 AA.
AC   P41586; A8K1Y1; B7ZLA7; B8ZZK3; Q17S10;
DE   RecName: Full=Pituitary adenylate cyclase-activating polypeptide type I receptor;
DE            Short=PACAP type I receptor;
DE            Short=PACAP-R-1;
DE            Short=PACAP-R1;
DE   Flags: Precursor;
GN   Name=ADCYAP1R1;
DR   GuidetoPHARMACOLOGY; 370; -.
DR   GO; GO:0042923; F:neuropeptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004999; F:vasoactive intestinal polypeptide receptor activity; IEA:InterPro.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:Reactome.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IEA:Ensembl.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0046545; P:development of primary female sexual characteristics; IEA:Ensembl.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:0060732; P:positive regulation of inositol phosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:Reactome.
//
ID   PACS1_HUMAN             Reviewed;         963 AA.
AC   Q6VY07; Q6PJY6; Q6PKB6; Q7Z590; Q7Z5W4; Q8N8K6; Q96MW0; Q9NW92;
AC   Q9ULP5;
DE   RecName: Full=Phosphofurin acidic cluster sorting protein 1;
DE            Short=PACS-1;
GN   Name=PACS1; Synonyms=KIAA1175;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:Ensembl.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PACRL_HUMAN             Reviewed;         248 AA.
AC   Q8N7B6; B2RDB9; B4DFF8; B4DMN7; Q8TBA8;
DE   RecName: Full=PACRG-like protein;
GN   Name=PACRGL; Synonyms=C4orf28;
//
ID   PACS2_HUMAN             Reviewed;         889 AA.
AC   Q86VP3; A2VDJ9; G8JLK3; O60342; Q6P191; Q96FL7;
DE   RecName: Full=Phosphofurin acidic cluster sorting protein 2;
DE            Short=PACS-2;
DE   AltName: Full=PACS1-like protein;
GN   Name=PACS2; Synonyms=KIAA0602, PACS1L;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PADC1_HUMAN             Reviewed;         188 AA.
AC   Q9BSG0; Q2Z1P2;
DE   RecName: Full=Protease-associated domain-containing protein 1;
DE   AltName: Full=Protease-associated domain-containing protein of 21 kDa;
DE            Short=hPAP21;
DE   Flags: Precursor;
GN   Name=PRADC1; Synonyms=C2orf7, PAP21; ORFNames=UNQ833/PRO1760;
//
ID   PADI1_HUMAN             Reviewed;         663 AA.
AC   Q9ULC6; A1L4K6; Q70SX6;
DE   RecName: Full=Protein-arginine deiminase type-1;
DE            EC=3.5.3.15;
DE   AltName: Full=Peptidylarginine deiminase I;
DE   AltName: Full=Protein-arginine deiminase type I;
GN   Name=PADI1; Synonyms=PDI1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018101; P:protein citrullination; IEA:InterPro.
//
ID   PADI3_HUMAN             Reviewed;         664 AA.
AC   Q9ULW8; Q58EY7; Q70SX5;
DE   RecName: Full=Protein-arginine deiminase type-3;
DE            EC=3.5.3.15;
DE   AltName: Full=Peptidylarginine deiminase III;
DE   AltName: Full=Protein-arginine deiminase type III;
GN   Name=PADI3; Synonyms=PDI3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; TAS:ProtInc.
DR   GO; GO:0018101; P:protein citrullination; IEA:InterPro.
//
ID   PADI4_HUMAN             Reviewed;         663 AA.
AC   Q9UM07; A8K392; B2RBW0; Q5VTZ8; Q70SX4;
DE   RecName: Full=Protein-arginine deiminase type-4;
DE            EC=3.5.3.15;
DE   AltName: Full=HL-60 PAD;
DE   AltName: Full=Peptidylarginine deiminase IV;
DE   AltName: Full=Protein-arginine deiminase type IV;
GN   Name=PADI4; Synonyms=PADI5, PDI5;
DR   GO; GO:0016990; F:arginine deiminase activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; ISS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; ISS:UniProtKB.
DR   GO; GO:0036414; P:histone citrullination; IDA:UniProtKB.
DR   GO; GO:0036413; P:histone H3-R26 citrullination; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; ISS:UniProtKB.
DR   GO; GO:0018101; P:protein citrullination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PADI2_HUMAN             Reviewed;         665 AA.
AC   Q9Y2J8; Q9UPN2;
DE   RecName: Full=Protein-arginine deiminase type-2;
DE            EC=3.5.3.15;
DE   AltName: Full=PAD-H19;
DE   AltName: Full=Peptidylarginine deiminase II;
DE   AltName: Full=Protein-arginine deiminase type II;
GN   Name=PADI2; Synonyms=KIAA0994, PDI2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030331; F:estrogen receptor binding; IPI:UniProt.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; IDA:UniProt.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProt.
DR   GO; GO:0036413; P:histone H3-R26 citrullination; IDA:UniProt.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0070100; P:negative regulation of chemokine-mediated signaling pathway; IDA:UniProt.
DR   GO; GO:1901624; P:negative regulation of lymphocyte chemotaxis; IDA:UniProt.
DR   GO; GO:0018101; P:protein citrullination; IDA:UniProt.
DR   GO; GO:0010848; P:regulation of chromatin disassembly; IDA:UniProt.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   PADI6_HUMAN             Reviewed;         694 AA.
AC   Q6TGC4; Q330K5; Q70SX3;
DE   RecName: Full=Protein-arginine deiminase type-6;
DE            EC=3.5.3.15;
DE   AltName: Full=Peptidyl arginine deiminase-like protein;
DE   AltName: Full=Peptidylarginine deiminase VI;
DE            Short=hPADVI;
DE   AltName: Full=Protein-arginine deiminase type VI;
GN   Name=PADI6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018101; P:protein citrullination; IEA:InterPro.
//
ID   PAEP_HUMAN              Reviewed;         180 AA.
AC   P09466; Q5T6T1; Q9UG92;
DE   RecName: Full=Glycodelin;
DE            Short=GD;
DE   AltName: Full=Placental protein 14;
DE            Short=PP14;
DE   AltName: Full=Pregnancy-associated endometrial alpha-2 globulin;
DE            Short=PAEG;
DE            Short=PEG;
DE   AltName: Full=Progestagen-associated endometrial protein;
DE   AltName: Full=Progesterone-associated endometrial protein;
DE   Flags: Precursor;
GN   Name=PAEP;
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   PAF15_HUMAN             Reviewed;         111 AA.
AC   Q15004; A6NNU5; A8K3Y3; G9G694; G9G696;
DE   RecName: Full=PCNA-associated factor;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 9;
DE            Short=HCV NS5A-transactivated protein 9;
DE   AltName: Full=Overexpressed in anaplastic thyroid carcinoma 1;
DE            Short=OEATC-1;
DE   AltName: Full=PCNA-associated factor of 15 kDa;
DE            Short=PAF15;
DE            Short=p15PAF;
GN   Name=KIAA0101; Synonyms=NS5ATP9, PAF; ORFNames=L5;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0019985; P:translesion synthesis; IMP:UniProtKB.
//
ID   PAF1_HUMAN              Reviewed;         531 AA.
AC   Q8N7H5; O75239; Q9H166; Q9NUU9;
DE   RecName: Full=RNA polymerase II-associated factor 1 homolog;
DE            Short=hPAF1;
DE   AltName: Full=Pancreatic differentiation protein 2;
GN   Name=PAF1; Synonyms=PD2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0031442; P:positive regulation of mRNA 3'-end processing; IMP:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   PAFA2_HUMAN             Reviewed;         392 AA.
AC   Q99487; D3DPK1; O15458; Q5SY02;
DE   RecName: Full=Platelet-activating factor acetylhydrolase 2, cytoplasmic;
DE            EC=3.1.1.47;
DE   AltName: Full=Serine-dependent phospholipase A2;
DE            Short=SD-PLA2;
DE            Short=hSD-PLA2;
GN   Name=PAFAH2;
DR   GO; GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
//
ID   PAFA_HUMAN              Reviewed;         441 AA.
AC   Q13093; A5HTT5; Q15692; Q5VTT1; Q8IVA2;
DE   RecName: Full=Platelet-activating factor acetylhydrolase;
DE            Short=PAF acetylhydrolase;
DE            EC=3.1.1.47;
DE   AltName: Full=1-alkyl-2-acetylglycerophosphocholine esterase;
DE   AltName: Full=2-acetyl-1-alkylglycerophosphocholine esterase;
DE   AltName: Full=Group-VIIA phospholipase A2;
DE            Short=gVIIA-PLA2;
DE   AltName: Full=LDL-associated phospholipase A2;
DE            Short=LDL-PLA(2);
DE   AltName: Full=PAF 2-acylhydrolase;
DE   Flags: Precursor;
GN   Name=PLA2G7; Synonyms=PAFAH;
DR   GuidetoPHARMACOLOGY; 1432; -.
DR   GO; GO:0003847; F:1-alkyl-2-acetylglycerophosphocholine esterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047499; F:calcium-independent phospholipase A2 activity; IDA:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0034440; P:lipid oxidation; IDA:BHF-UCL.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0034441; P:plasma lipoprotein particle oxidation; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; TAS:BHF-UCL.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:BHF-UCL.
//
ID   PAG15_HUMAN             Reviewed;         412 AA.
AC   Q8NCC3; B3KMF3; Q53GZ1; Q9NPQ6; Q9UG04; Q9Y2B3;
DE   RecName: Full=Group XV phospholipase A2;
DE            EC=2.3.1.-;
DE   AltName: Full=1-O-acylceramide synthase;
DE            Short=ACS;
DE   AltName: Full=LCAT-like lysophospholipase;
DE            Short=LLPL;
DE   AltName: Full=Lysophospholipase 3;
DE   AltName: Full=Lysosomal phospholipase A2;
DE            Short=LPLA2;
DE   Flags: Precursor;
GN   Name=PLA2G15; Synonyms=LYPLA3; ORFNames=UNQ341/PRO540;
DR   GO; GO:0047499; F:calcium-independent phospholipase A2 activity; ISS:UniProtKB.
DR   GO; GO:0004622; F:lysophospholipase activity; TAS:ProtInc.
DR   GO; GO:0008374; F:O-acyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0006672; P:ceramide metabolic process; IEA:Ensembl.
DR   GO; GO:0009062; P:fatty acid catabolic process; TAS:ProtInc.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IEA:Ensembl.
//
ID   PAGE2_HUMAN             Reviewed;         111 AA.
AC   Q7Z2X7; Q5JRK7; Q5JRK8;
DE   RecName: Full=P antigen family member 2;
DE            Short=PAGE-2;
DE   AltName: Full=G antigen family C 2;
DE   AltName: Full=Prostate-associated gene 2 protein;
GN   Name=PAGE2; Synonyms=GAGEC2, GAGEE2;
//
ID   PAGE1_HUMAN             Reviewed;         146 AA.
AC   O75459; Q6FGM3; Q9BSS7;
DE   RecName: Full=P antigen family member 1;
DE            Short=PAGE-1;
DE   AltName: Full=AL5;
DE   AltName: Full=G antigen 9;
DE            Short=GAGE-9;
DE   AltName: Full=G antigen family B member 1;
DE   AltName: Full=Prostate-associated gene 1 protein;
GN   Name=PAGE1; Synonyms=GAGE9, GAGEB1;
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
//
ID   PAGE3_HUMAN             Reviewed;         113 AA.
AC   Q5JUK9; A5D6Y1;
DE   RecName: Full=P antigen family member 3;
DE            Short=PAGE-3;
DE   AltName: Full=G antigen family D member 1;
DE   AltName: Full=Prostate-associated gene 3 protein;
GN   Name=PAGE3; Synonyms=GAGED1;
//
ID   PAGE4_HUMAN             Reviewed;         102 AA.
AC   O60829; B2R529; D3DX68; Q6IBI1;
DE   RecName: Full=P antigen family member 4;
DE            Short=PAGE-4;
DE   AltName: Full=G antigen family C member 1;
DE   AltName: Full=PAGE-1;
GN   Name=PAGE4; Synonyms=GAGEC1; ORFNames=JM27;
//
ID   PAGE5_HUMAN             Reviewed;         130 AA.
AC   Q96GU1; Q2NL97; Q5JUL0; Q8WWL9;
DE   RecName: Full=P antigen family member 5;
DE            Short=PAGE-5;
DE   AltName: Full=Cancer/testis antigen 16.1;
DE            Short=CT16.1;
DE   AltName: Full=G antigen family E member 1;
DE   AltName: Full=Prostate-associated gene 5 protein;
GN   Name=PAGE5; Synonyms=GAGEE1;
//
ID   PAGR1_HUMAN             Reviewed;         254 AA.
AC   Q9BTK6; A2ICR6;
DE   RecName: Full=PAXIP1-associated glutamate-rich protein 1;
DE   AltName: Full=PAXIP1-associated protein 1;
DE   AltName: Full=PTIP-associated protein 1;
GN   Name=PAGR1; Synonyms=C16orf53, PA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PAHO_HUMAN              Reviewed;          95 AA.
AC   P01298;
DE   RecName: Full=Pancreatic prohormone;
DE   AltName: Full=Pancreatic polypeptide;
DE            Short=PP;
DE   AltName: INN=Obinepitide;
DE   Contains:
DE     RecName: Full=Pancreatic hormone;
DE              Short=PH;
DE   Contains:
DE     RecName: Full=Pancreatic icosapeptide;
DE              Short=PI;
DE   Flags: Precursor;
GN   Name=PPY; Synonyms=PNP;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0009306; P:protein secretion; TAS:ProtInc.
//
ID   PAHX_HUMAN              Reviewed;         338 AA.
AC   O14832; A8MTS8; B1ALH5;
DE   RecName: Full=Phytanoyl-CoA dioxygenase, peroxisomal;
DE            EC=1.14.11.18;
DE   AltName: Full=Phytanic acid oxidase;
DE   AltName: Full=Phytanoyl-CoA alpha-hydroxylase;
DE            Short=PhyH;
DE   Flags: Precursor;
GN   Name=PHYH; Synonyms=PAHX;
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048244; F:phytanoyl-CoA dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; IDA:UniProtKB.
DR   GO; GO:0006720; P:isoprenoid metabolic process; IDA:UniProtKB.
DR   GO; GO:0097089; P:methyl-branched fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PAI1_HUMAN              Reviewed;         402 AA.
AC   P05121; B7Z4S0; F8WD53;
DE   RecName: Full=Plasminogen activator inhibitor 1;
DE            Short=PAI;
DE            Short=PAI-1;
DE   AltName: Full=Endothelial plasminogen activator inhibitor;
DE   AltName: Full=Serpin E1;
DE   Flags: Precursor;
GN   Name=SERPINE1; Synonyms=PAI1, PLANH1;
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0001300; P:chronological cell aging; IEP:BHF-UCL.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IGI:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IC:BHF-UCL.
DR   GO; GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0010757; P:negative regulation of plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:2000098; P:negative regulation of smooth muscle cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0061044; P:negative regulation of vascular wound healing; IGI:BHF-UCL.
DR   GO; GO:0061045; P:negative regulation of wound healing; IC:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IMP:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IGI:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IMP:BHF-UCL.
DR   GO; GO:0035491; P:positive regulation of leukotriene production involved in inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IMP:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010469; P:regulation of receptor activity; IDA:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   PAI2_HUMAN              Reviewed;         415 AA.
AC   P05120; Q96E96;
DE   RecName: Full=Plasminogen activator inhibitor 2;
DE            Short=PAI-2;
DE   AltName: Full=Monocyte Arg-serpin;
DE   AltName: Full=Placental plasminogen activator inhibitor;
DE   AltName: Full=Serpin B2;
DE   AltName: Full=Urokinase inhibitor;
DE   Flags: Precursor;
GN   Name=SERPINB2; Synonyms=PAI2, PLANH2;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   PAI2B_HUMAN             Reviewed;         123 AA.
AC   Q9ULR5;
DE   RecName: Full=Polyadenylate-binding protein-interacting protein 2B;
DE            Short=PABP-interacting protein 2B;
DE            Short=PAIP-2B;
DE            Short=Poly(A)-binding protein-interacting protein 2B;
GN   Name=PAIP2B; Synonyms=KIAA1155;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; IDA:HGNC.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IDA:HGNC.
//
ID   PAIP1_HUMAN             Reviewed;         479 AA.
AC   Q9H074; A6NKV8; O60455; Q96B61; Q9BS63;
DE   RecName: Full=Polyadenylate-binding protein-interacting protein 1;
DE            Short=PABP-interacting protein 1;
DE            Short=PAIP-1;
DE            Short=Poly(A)-binding protein-interacting protein 1;
GN   Name=PAIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008494; F:translation activator activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0048255; P:mRNA stabilization; TAS:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:GOC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:ProtInc.
//
ID   PAIP2_HUMAN             Reviewed;         127 AA.
AC   Q9BPZ3; B2RBI1; D3DQC6; Q49A06; Q9H0Y5; Q9P0Q8;
DE   RecName: Full=Polyadenylate-binding protein-interacting protein 2;
DE            Short=PABP-interacting protein 2;
DE            Short=PAIP-2;
DE            Short=Poly(A)-binding protein-interacting protein 2;
GN   Name=PAIP2; Synonyms=PAIP2A; ORFNames=HSPC218;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030371; F:translation repressor activity; IDA:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IDA:UniProtKB.
//
ID   PAIRB_HUMAN             Reviewed;         408 AA.
AC   Q8NC51; Q5VU19; Q5VU20; Q5VU22; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4;
AC   Q9Y367; Q9Y4S3;
DE   RecName: Full=Plasminogen activator inhibitor 1 RNA-binding protein;
DE   AltName: Full=PAI1 RNA-binding protein 1;
DE            Short=PAI-RBP1;
DE   AltName: Full=SERPINE1 mRNA-binding protein 1;
GN   Name=SERBP1; Synonyms=PAIRBP1; ORFNames=CGI-55;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:HGNC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043488; P:regulation of mRNA stability; NAS:HGNC.
//
ID   PAK1_HUMAN              Reviewed;         545 AA.
AC   Q13153; O75561; Q13567; Q32M53; Q32M54; Q86W79;
DE   RecName: Full=Serine/threonine-protein kinase PAK 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Alpha-PAK;
DE   AltName: Full=p21-activated kinase 1;
DE            Short=PAK-1;
DE   AltName: Full=p65-PAK;
GN   Name=PAK1;
DR   GuidetoPHARMACOLOGY; 2133; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005518; F:collagen binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IMP:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; IMP:UniProtKB.
//
ID   PAK2_HUMAN              Reviewed;         524 AA.
AC   Q13177; Q13154; Q6ISC3;
DE   RecName: Full=Serine/threonine-protein kinase PAK 2;
DE            EC=2.7.11.1;
DE   AltName: Full=Gamma-PAK;
DE   AltName: Full=PAK65;
DE   AltName: Full=S6/H4 kinase;
DE   AltName: Full=p21-activated kinase 2;
DE            Short=PAK-2;
DE   AltName: Full=p58;
DE   Contains:
DE     RecName: Full=PAK-2p27;
DE              Short=p27;
DE   Contains:
DE     RecName: Full=PAK-2p34;
DE              Short=p34;
DE     AltName: Full=C-t-PAK2;
GN   Name=PAK2;
DR   GuidetoPHARMACOLOGY; 2134; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0030296; F:protein tyrosine kinase activator activity; IDA:BHF-UCL.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007409; P:axonogenesis; IBA:RefGenome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001271; P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:ProtInc.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:MGI.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:MGI.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PAK3_HUMAN              Reviewed;         559 AA.
AC   O75914; A8K389; B1GX77; B1GX78; B1GX79; Q5JWX1; Q5JWX2; Q7Z2D6;
AC   Q7Z2E4; Q7Z3Z8; Q8WWK5; Q8WX23; Q9P0J8;
DE   RecName: Full=Serine/threonine-protein kinase PAK 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Beta-PAK;
DE   AltName: Full=Oligophrenin-3;
DE   AltName: Full=p21-activated kinase 3;
DE            Short=PAK-3;
GN   Name=PAK3; Synonyms=OPHN3;
DR   GuidetoPHARMACOLOGY; 2135; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:GOC.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; ISS:UniProtKB.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; TAS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:GOC.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
DR   GO; GO:0050808; P:synapse organization; TAS:UniProtKB.
//
ID   PAK4_HUMAN              Reviewed;         591 AA.
AC   O96013; B4DGG6; Q8N4E1; Q8NCH5; Q8NDE3; Q9BU33; Q9ULS8;
DE   RecName: Full=Serine/threonine-protein kinase PAK 4;
DE            EC=2.7.11.1;
DE   AltName: Full=p21-activated kinase 4;
DE            Short=PAK-4;
GN   Name=PAK4; Synonyms=KIAA1142;
DR   GuidetoPHARMACOLOGY; 2136; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; NAS:ProtInc.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016049; P:cell growth; TAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   PAK6_HUMAN              Reviewed;         681 AA.
AC   Q9NQU5; A8K2G2;
DE   RecName: Full=Serine/threonine-protein kinase PAK 6;
DE            EC=2.7.11.1;
DE   AltName: Full=PAK-5;
DE   AltName: Full=p21-activated kinase 6;
DE            Short=PAK-6;
GN   Name=PAK6; Synonyms=PAK5;
DR   GuidetoPHARMACOLOGY; 2137; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   PAK7_HUMAN              Reviewed;         719 AA.
AC   Q9P286; A8K5T6; D3DW14; Q5W115; Q9BX09; Q9ULF6;
DE   RecName: Full=Serine/threonine-protein kinase PAK 7;
DE            EC=2.7.11.1;
DE   AltName: Full=p21-activated kinase 5;
DE            Short=PAK-5;
DE   AltName: Full=p21-activated kinase 7;
DE            Short=PAK-7;
GN   Name=PAK7; Synonyms=KIAA1264, PAK5;
DR   GuidetoPHARMACOLOGY; 2138; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; TAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   PAL4D_HUMAN             Reviewed;         164 AA.
AC   F5H284;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase A-like 4D;
DE            Short=PPIase A-like 4D;
DE            EC=5.2.1.8;
GN   Name=PPIAL4D;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PAL4A_HUMAN             Reviewed;         164 AA.
AC   Q9Y536;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase A-like 4A/B/C;
DE            Short=PPIase A-like 4A;
DE            EC=5.2.1.8;
DE   AltName: Full=Chromosome 1-amplified sequence 2;
DE            Short=COAS-2;
DE   AltName: Full=Cyclophilin homolog overexpressed in liver cancer;
GN   Name=PPIAL4A; Synonyms=COAS2;
GN   and
GN   Name=PPIAL4B;
GN   and
GN   Name=PPIAL4C;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PAL4G_HUMAN             Reviewed;         164 AA.
AC   A2BFH1; A1L431;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase A-like 4G;
DE            Short=PPIase A-like 4G;
DE            EC=5.2.1.8;
DE   AltName: Full=Peptidylprolyl cis-trans isomerase A-like 4;
GN   Name=PPIAL4G;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PALB2_HUMAN             Reviewed;        1186 AA.
AC   Q86YC2; A6NIE1; Q8N7Y6; Q8ND31; Q9H6W1;
DE   RecName: Full=Partner and localizer of BRCA2;
GN   Name=PALB2; Synonyms=FANCN;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   PALD_HUMAN              Reviewed;         856 AA.
AC   Q9ULE6; B2RMS1; B9EGC6; Q5JTK7; Q5JTK8;
DE   RecName: Full=Paladin;
GN   Name=PALD1; Synonyms=KIAA1274, PALD;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PALLD_HUMAN             Reviewed;        1383 AA.
AC   Q8WX93; B3KTG2; B5MD56; B7ZMM5; Q7L3E0; Q7Z3W0; Q86WE8; Q8N1M2;
AC   Q9UGA0; Q9UQF5; Q9Y2J6; Q9Y3E9;
DE   RecName: Full=Palladin;
DE   AltName: Full=SIH002;
DE   AltName: Full=Sarcoma antigen NY-SAR-77;
GN   Name=PALLD; Synonyms=KIAA0992; ORFNames=CGI-151;
DR   GO; GO:0051371; F:muscle alpha-actinin binding; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:HGNC.
//
ID   PALM2_HUMAN             Reviewed;         379 AA.
AC   Q8IXS6; A9Z1X9; Q8N9D5; Q96DU1;
DE   RecName: Full=Paralemmin-2;
DE   Flags: Precursor;
GN   Name=PALM2;
DR   GO; GO:0008360; P:regulation of cell shape; IEA:InterPro.
//
ID   PALM3_HUMAN             Reviewed;         673 AA.
AC   A6NDB9;
DE   RecName: Full=Paralemmin-3;
DE   Flags: Precursor;
GN   Name=PALM3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0008063; P:Toll signaling pathway; IMP:UniProtKB.
//
ID   PALMD_HUMAN             Reviewed;         551 AA.
AC   Q9NP74; Q9H7E6; Q9NPM5; Q9NPM6; Q9NPS0;
DE   RecName: Full=Palmdelphin;
DE   AltName: Full=Paralemmin-like protein;
GN   Name=PALMD; Synonyms=C1orf11, PALML;
DR   GO; GO:0008360; P:regulation of cell shape; IEA:InterPro.
//
ID   PALM_HUMAN              Reviewed;         387 AA.
AC   O75781; O43359; O95673; Q92559; Q9UPJ4; Q9UQS2; Q9UQS3;
DE   RecName: Full=Paralemmin-1;
DE   AltName: Full=Paralemmin;
DE   Flags: Precursor;
GN   Name=PALM; Synonyms=KIAA0270;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007194; P:negative regulation of adenylate cyclase activity; IDA:UniProtKB.
DR   GO; GO:0060160; P:negative regulation of dopamine receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; IEA:Ensembl.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0060074; P:synapse maturation; IEA:Ensembl.
//
ID   PAMR1_HUMAN             Reviewed;         720 AA.
AC   Q6UXH9; Q5EBL7; Q5JPI4; Q6N062; Q71RE9; Q96JW2; Q9Y432;
DE   RecName: Full=Inactive serine protease PAMR1;
DE   AltName: Full=Peptidase domain-containing protein associated with muscle regeneration 1;
DE   AltName: Full=Regeneration-associated muscle protease homolog;
DE   Flags: Precursor;
GN   Name=PAMR1; Synonyms=RAMP; ORFNames=FP938, UNQ699/PRO1344;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   PAN2_HUMAN              Reviewed;        1202 AA.
AC   Q504Q3; O75189; Q76E12; Q8IVE1;
DE   RecName: Full=PAB-dependent poly(A)-specific ribonuclease subunit PAN2;
DE            Short=hPan2;
DE            EC=3.1.13.4;
DE   AltName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 52;
DE   AltName: Full=PAB1P-dependent poly(A)-nuclease;
DE   AltName: Full=PAN deadenylation complex catalytic subunit 2;
GN   Name=PAN2; Synonyms=KIAA0710, USP52;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
//
ID   PAN3_HUMAN              Reviewed;         887 AA.
AC   Q58A45; A0N0X1; A1A4Y8; A1A4Y9; B1ALF1; B7Z3W7; Q0D2P2; Q5HYG6;
AC   Q5T515; Q5T516; Q5TBA0; Q76E13; Q8NBA6;
DE   RecName: Full=PAB-dependent poly(A)-specific ribonuclease subunit PAN3;
DE   AltName: Full=PAB1P-dependent poly(A)-nuclease;
DE   AltName: Full=PAN deadenylation complex subunit 3;
DE            Short=hPan3;
GN   Name=PAN3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0010606; P:positive regulation of cytoplasmic mRNA processing body assembly; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
//
ID   PANK1_HUMAN             Reviewed;         598 AA.
AC   Q8TE04; A6NIP0; Q7RTX6; Q7Z495; Q8TBQ8;
DE   RecName: Full=Pantothenate kinase 1;
DE            Short=hPanK;
DE            Short=hPanK1;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase 1;
GN   Name=PANK1; Synonyms=PANK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009108; P:coenzyme biosynthetic process; TAS:Reactome.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PANK2_HUMAN             Reviewed;         570 AA.
AC   Q9BZ23; B1AK33; B2Z3X0; D3DVZ0; Q5T7I2; Q5T7I4; Q7RTX5; Q8N7Q4;
AC   Q8TCR5; Q9BYW5; Q9HAF2;
DE   RecName: Full=Pantothenate kinase 2, mitochondrial;
DE            Short=hPanK2;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase 2;
DE   Flags: Precursor;
GN   Name=PANK2; Synonyms=C20orf48;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009060; P:aerobic respiration; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009108; P:coenzyme biosynthetic process; TAS:Reactome.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PANK3_HUMAN             Reviewed;         370 AA.
AC   Q9H999; D3DQL1; Q53FJ9; Q7RTX4;
DE   RecName: Full=Pantothenate kinase 3;
DE            Short=hPanK3;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase 3;
GN   Name=PANK3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   PANK4_HUMAN             Reviewed;         773 AA.
AC   Q9NVE7; B9DI84; Q53EU3; Q5TA84; Q7RTX3; Q9H3X5;
DE   RecName: Full=Pantothenate kinase 4;
DE            Short=hPanK4;
DE            EC=2.7.1.33;
DE   AltName: Full=Pantothenic acid kinase 4;
GN   Name=PANK4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004594; F:pantothenate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   PANX1_HUMAN             Reviewed;         426 AA.
AC   Q96RD7; O75968; Q543A0; Q6UW26; Q96AM9; Q96L77; Q96RS5;
DE   RecName: Full=Pannexin-1;
GN   Name=PANX1; Synonyms=MRS1; ORFNames=UNQ2529/PRO6028;
DR   GuidetoPHARMACOLOGY; 735; -.
DR   GO; GO:0005262; F:calcium channel activity; IMP:UniProtKB.
DR   GO; GO:0055077; F:gap junction hemi-channel activity; IDA:UniProtKB.
DR   GO; GO:0022840; F:leak channel activity; IMP:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0006812; P:cation transport; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050717; P:positive regulation of interleukin-1 alpha secretion; IEA:Ensembl.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:BHF-UCL.
DR   GO; GO:0034214; P:protein hexamerization; IDA:UniProtKB.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   PANX2_HUMAN             Reviewed;         677 AA.
AC   Q96RD6; B7Z684; Q96RD5; Q9UGX8;
DE   RecName: Full=Pannexin-2;
GN   Name=PANX2;
DR   GuidetoPHARMACOLOGY; 736; -.
DR   GO; GO:0055077; F:gap junction hemi-channel activity; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0034214; P:protein hexamerization; ISS:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   PANX3_HUMAN             Reviewed;         392 AA.
AC   Q96QZ0;
DE   RecName: Full=Pannexin-3;
GN   Name=PANX3;
DR   GuidetoPHARMACOLOGY; 737; -.
DR   GO; GO:0055077; F:gap junction hemi-channel activity; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0034214; P:protein hexamerization; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; ISS:GOC.
//
ID   PAOX_HUMAN              Reviewed;         649 AA.
AC   Q6QHF9; D3DXI6; Q5VWY0; Q6QHF5; Q6QHF6; Q6QHF7; Q6QHF8; Q6QHG0;
AC   Q6QHG1; Q6QHG2; Q6QHG3; Q6QHG4; Q6QHG5; Q6QHG6; Q86WP9; Q8N555;
AC   Q8NCX3;
DE   RecName: Full=Peroxisomal N(1)-acetyl-spermine/spermidine oxidase;
DE            EC=1.5.3.13;
DE   AltName: Full=Polyamine oxidase;
GN   Name=PAOX; Synonyms=PAO; ORFNames=UNQ1923/PRO4398;
DR   GO; GO:0052899; F:N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0052904; F:N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; TAS:Reactome.
DR   GO; GO:0052903; F:N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046592; F:polyamine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0052902; F:spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0052901; F:spermine:oxygen oxidoreductase (spermidine-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0006596; P:polyamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006598; P:polyamine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:1901307; P:positive regulation of spermidine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009446; P:putrescine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009447; P:putrescine catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046203; P:spermidine catabolic process; IDA:UniProtKB.
DR   GO; GO:0046208; P:spermine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   PAP1L_HUMAN             Reviewed;         614 AA.
AC   Q4VXU2;
DE   RecName: Full=Polyadenylate-binding protein 1-like;
GN   Name=PABPC1L; Synonyms=C20orf119;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   PAP1M_HUMAN             Reviewed;         200 AA.
AC   Q5JQF8; B2RMV9; Q8IVU8;
DE   RecName: Full=Polyadenylate-binding protein 1-like 2;
DE   AltName: Full=RNA-binding motif protein 32;
DE   AltName: Full=RNA-binding protein 32;
GN   Name=PABPC1L2A; Synonyms=PABPC1L2, RBM32A;
GN   and
GN   Name=PABPC1L2B; Synonyms=PABPC1L2, RBM32B;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   PAPAS_HUMAN             Reviewed;         102 AA.
AC   Q5QFB9;
DE   RecName: Full=Protein PAPPAS;
DE   AltName: Full=DIPLA1 antisense RNA 1;
DE   AltName: Full=DIPLA1 antisense gene protein 1;
DE   AltName: Full=DIPLA1-antisense expressed;
DE   AltName: Full=PAPPAS antisense RNA 1;
DE   AltName: Full=PAPPAS antisense gene protein 1;
DE   AltName: Full=PAPPAS-antisense expressed;
GN   Name=PAPPA-AS1; Synonyms=DIPAS, PAPPAS;
//
ID   PAPD1_HUMAN             Reviewed;         582 AA.
AC   Q9NVV4; D3DRX0; Q659E3; Q6P7E5; Q9HA74;
DE   RecName: Full=Poly(A) RNA polymerase, mitochondrial;
DE            Short=PAP;
DE            EC=2.7.7.19;
DE   AltName: Full=PAP-associated domain-containing protein 1;
DE   AltName: Full=Polynucleotide adenylyltransferase;
DE   AltName: Full=Terminal uridylyltransferase 1;
DE            Short=TUTase 1;
DE   AltName: Full=mtPAP;
DE   Flags: Precursor;
GN   Name=MTPAP; Synonyms=PAPD1;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0002134; F:UTP binding; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAPD5_HUMAN             Reviewed;         572 AA.
AC   Q8NDF8; B4DV38; Q9NW67; Q9Y6C0;
DE   RecName: Full=Non-canonical poly(A) RNA polymerase PAPD5;
DE            EC=2.7.7.19;
DE   AltName: Full=PAP-associated domain-containing protein 5;
DE   AltName: Full=Terminal uridylyltransferase 3;
DE            Short=TUTase 3;
DE   AltName: Full=Topoisomerase-related function protein 4-2;
DE            Short=TRF4-2;
GN   Name=PAPD5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   PAPD7_HUMAN             Reviewed;         772 AA.
AC   Q5XG87; A8K1E2; M1JCE6; O43289; Q17RZ1; Q9Y6C1;
DE   RecName: Full=Non-canonical poly(A) RNA polymerase PAPD7;
DE            EC=2.7.7.19;
DE   AltName: Full=DNA polymerase sigma;
DE   AltName: Full=LAK-1;
DE   AltName: Full=PAP-associated domain-containing protein 7;
DE   AltName: Full=TRAMP-like complex polyadenylate polymerase;
DE   AltName: Full=Terminal uridylyltransferase 5;
DE            Short=TUTase 5;
DE   AltName: Full=Topoisomerase-related function protein 4-1;
DE            Short=TRF4-1;
GN   Name=PAPD7; Synonyms=POLS, TRF4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043221; F:SMC family protein binding; TAS:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; NAS:UniProtKB.
DR   GO; GO:0007076; P:mitotic chromosome condensation; NAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0007062; P:sister chromatid cohesion; TAS:UniProtKB.
//
ID   PAPL_HUMAN              Reviewed;         438 AA.
AC   Q6ZNF0; B2RN68;
DE   RecName: Full=Iron/zinc purple acid phosphatase-like protein;
DE            EC=3.1.3.2;
DE   Flags: Precursor;
GN   Name=PAPL;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   PAPOA_HUMAN             Reviewed;         745 AA.
AC   P51003; Q86SX4; Q86TV0; Q8IYF5; Q9BVU2;
DE   RecName: Full=Poly(A) polymerase alpha;
DE            Short=PAP-alpha;
DE            EC=2.7.7.19;
DE   AltName: Full=Polynucleotide adenylyltransferase alpha;
GN   Name=PAPOLA; Synonyms=PAP;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; ISS:UniProtKB.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0043631; P:RNA polyadenylation; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   PAPOB_HUMAN             Reviewed;         636 AA.
AC   Q9NRJ5; Q75LH1; Q8NE14;
DE   RecName: Full=Poly(A) polymerase beta;
DE            Short=PAP-beta;
DE            EC=2.7.7.19;
DE   AltName: Full=Polynucleotide adenylyltransferase beta;
DE   AltName: Full=Testis-specific poly(A) polymerase;
GN   Name=PAPOLB; Synonyms=PAPT;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IBA:RefGenome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006378; P:mRNA polyadenylation; IBA:RefGenome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:RefGenome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; IBA:RefGenome.
//
ID   PAPOG_HUMAN             Reviewed;         736 AA.
AC   Q9BWT3; B2RBH4; Q59G05; Q969N1; Q9H8L2; Q9HAD0;
DE   RecName: Full=Poly(A) polymerase gamma;
DE            Short=PAP-gamma;
DE            EC=2.7.7.19;
DE   AltName: Full=Neo-poly(A) polymerase;
DE            Short=Neo-PAP;
DE   AltName: Full=Polynucleotide adenylyltransferase gamma;
DE   AltName: Full=SRP RNA 3'-adenylating enzyme;
GN   Name=PAPOLG; Synonyms=PAP2, PAPG;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IDA:UniProtKB.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006378; P:mRNA polyadenylation; IBA:RefGenome.
DR   GO; GO:0043631; P:RNA polyadenylation; IEA:InterPro.
//
ID   PAPP1_HUMAN             Reviewed;        1627 AA.
AC   Q13219; B1AMF9; Q08371; Q68G52; Q9UDK7;
DE   RecName: Full=Pappalysin-1;
DE            EC=3.4.24.79;
DE   AltName: Full=Insulin-like growth factor-dependent IGF-binding protein 4 protease;
DE            Short=IGF-dependent IGFBP-4 protease;
DE            Short=IGFBP-4ase;
DE   AltName: Full=Pregnancy-associated plasma protein A;
DE            Short=PAPP-A;
DE   Flags: Precursor;
GN   Name=PAPPA;
DR   GO; GO:0004175; F:endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007565; P:female pregnancy; NAS:UniProtKB.
DR   GO; GO:0032354; P:response to follicle-stimulating hormone; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
//
ID   PAPP2_HUMAN             Reviewed;        1791 AA.
AC   Q9BXP8; A9Z1Y8; Q96PH7; Q96PH8; Q9H4C9;
DE   RecName: Full=Pappalysin-2;
DE            EC=3.4.24.-;
DE   AltName: Full=Pregnancy-associated plasma protein A2;
DE            Short=PAPP-A2;
DE   AltName: Full=Pregnancy-associated plasma protein E1;
DE            Short=PAPP-E;
DE   Flags: Precursor;
GN   Name=PAPPA2; Synonyms=PLAC3;
DR   GO; GO:0008237; F:metallopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   PAPS1_HUMAN             Reviewed;         624 AA.
AC   O43252; O43841; O75332; Q96FB1; Q96TF4; Q9P1P9; Q9UE98;
DE   RecName: Full=Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1;
DE            Short=PAPS synthase 1;
DE            Short=PAPSS 1;
DE   AltName: Full=Sulfurylase kinase 1;
DE            Short=SK 1;
DE            Short=SK1;
DE   Includes:
DE     RecName: Full=Sulfate adenylyltransferase;
DE              EC=2.7.7.4;
DE     AltName: Full=ATP-sulfurylase;
DE     AltName: Full=Sulfate adenylate transferase;
DE              Short=SAT;
DE   Includes:
DE     RecName: Full=Adenylyl-sulfate kinase;
DE              EC=2.7.1.25;
DE     AltName: Full=3'-phosphoadenosine-5'-phosphosulfate synthase;
DE     AltName: Full=APS kinase;
DE     AltName: Full=Adenosine-5'-phosphosulfate 3'-phosphotransferase;
DE     AltName: Full=Adenylylsulfate 3'-phosphotransferase;
GN   Name=PAPSS1; Synonyms=ATPSK1, PAPSS;
DR   GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; ISS:UniProtKB.
DR   GO; GO:0050428; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   PAPS2_HUMAN             Reviewed;         614 AA.
AC   O95340; Q9BZL2; Q9P0G6; Q9UHM1; Q9UKD3; Q9UP30;
DE   RecName: Full=Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2;
DE            Short=PAPS synthase 2;
DE            Short=PAPSS 2;
DE   AltName: Full=Sulfurylase kinase 2;
DE            Short=SK 2;
DE            Short=SK2;
DE   Includes:
DE     RecName: Full=Sulfate adenylyltransferase;
DE              EC=2.7.7.4;
DE     AltName: Full=ATP-sulfurylase;
DE     AltName: Full=Sulfate adenylate transferase;
DE              Short=SAT;
DE   Includes:
DE     RecName: Full=Adenylyl-sulfate kinase;
DE              EC=2.7.1.25;
DE     AltName: Full=3'-phosphoadenosine-5'-phosphosulfate synthase;
DE     AltName: Full=APS kinase;
DE     AltName: Full=Adenosine-5'-phosphosulfate 3'-phosphotransferase;
DE     AltName: Full=Adenylylsulfate 3'-phosphotransferase;
GN   Name=PAPSS2; Synonyms=ATPSK2;
DR   GO; GO:0004020; F:adenylylsulfate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0004781; F:sulfate adenylyltransferase (ATP) activity; ISS:UniProtKB.
DR   GO; GO:0050428; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   PAQR3_HUMAN             Reviewed;         311 AA.
AC   Q6TCH7; A8K5B7; B3KP59; Q6PIQ1; Q86X05; Q8NCP9;
DE   RecName: Full=Progestin and adipoQ receptor family member 3;
DE   AltName: Full=Progestin and adipoQ receptor family member III;
DE   AltName: Full=Raf kinase trapping to Golgi;
DE            Short=RKTG;
GN   Name=PAQR3;
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:MGI.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:MGI.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IPI:MGI.
//
ID   PAQR6_HUMAN             Reviewed;         344 AA.
AC   Q6TCH4; B7Z9R9; D3DVB4; D3DVB6; Q5TCK9; Q6PDU0; Q7Z4Q7; Q7Z4Q9;
AC   Q8N121; Q8N3M2; Q9H621;
DE   RecName: Full=Progestin and adipoQ receptor family member 6;
DE   AltName: Full=Progestin and adipoQ receptor family member VI;
GN   Name=PAQR6;
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
//
ID   PAQR4_HUMAN             Reviewed;         273 AA.
AC   Q8N4S7; A8K5Q8; D3DUA2; D3DUA3; Q8NAS6; Q96NW1;
DE   RecName: Full=Progestin and adipoQ receptor family member 4;
DE   AltName: Full=Progestin and adipoQ receptor family member IV;
GN   Name=PAQR4;
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
//
ID   PAQR9_HUMAN             Reviewed;         377 AA.
AC   Q6ZVX9; Q147T6;
DE   RecName: Full=Progestin and adipoQ receptor family member 9;
DE   AltName: Full=Progestin and adipoQ receptor family member IX;
GN   Name=PAQR9;
DR   GO; GO:0004872; F:receptor activity; IBA:RefGenome.
//
ID   PAQRA_HUMAN             Reviewed;         270 AA.
AC   Q8IY49; B5MBW4; Q6NVU5; Q6TCH0;
DE   RecName: Full=Monocyte to macrophage differentiation factor 2;
DE   AltName: Full=Progestin and adipoQ receptor family member 10;
DE   AltName: Full=Progestin and adipoQ receptor family member X;
GN   Name=MMD2; Synonyms=PAQR10;
//
ID   PAR10_HUMAN             Reviewed;        1025 AA.
AC   Q53GL7; Q8N2I0; Q8WV05; Q96CH7; Q96K72;
DE   RecName: Full=Poly [ADP-ribose] polymerase 10;
DE            Short=PARP-10;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 10;
DE            Short=ARTD10;
GN   Name=PARP10;
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IMP:UniProt.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProt.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProt.
DR   GO; GO:0033159; P:negative regulation of protein import into nucleus, translocation; IMP:UniProt.
DR   GO; GO:1900045; P:negative regulation of protein K63-linked ubiquitination; IMP:UniProt.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProt.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IMP:UniProt.
DR   GO; GO:0070213; P:protein auto-ADP-ribosylation; IMP:UniProt.
DR   GO; GO:0070212; P:protein poly-ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0010847; P:regulation of chromatin assembly; IDA:UniProtKB.
//
ID   PAR11_HUMAN             Reviewed;         331 AA.
AC   Q9NR21; B4DRQ0; Q68DS1; Q8N5Y9;
DE   RecName: Full=Poly [ADP-ribose] polymerase 11;
DE            Short=PARP-11;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 11;
DE            Short=ARTD11;
GN   Name=PARP11; Synonyms=C12orf6;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
//
ID   PAR14_HUMAN             Reviewed;        1801 AA.
AC   Q460N5; B4E2H0; Q460N4; Q8J027; Q9H9X9; Q9NV60; Q9ULF2;
DE   RecName: Full=Poly [ADP-ribose] polymerase 14;
DE            Short=PARP-14;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 8;
DE            Short=ARTD8;
DE   AltName: Full=B aggressive lymphoma protein 2;
GN   Name=PARP14; Synonyms=BAL2, KIAA1268;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAQRB_HUMAN             Reviewed;         238 AA.
AC   Q15546; B2R6X9; D3DTY6; Q8TAN7;
DE   RecName: Full=Monocyte to macrophage differentiation factor;
DE   AltName: Full=Progestin and adipoQ receptor family member 11;
DE   AltName: Full=Progestin and adipoQ receptor family member XI;
GN   Name=MMD; Synonyms=PAQR11;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0019835; P:cytolysis; IEA:InterPro.
//
ID   PAR15_HUMAN             Reviewed;         678 AA.
AC   Q460N3; J3KR47; Q8N1K3;
DE   RecName: Full=Poly [ADP-ribose] polymerase 15;
DE            Short=PARP-15;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 7;
DE            Short=ARTD7;
DE   AltName: Full=B-aggressive lymphoma protein 3;
GN   Name=PARP15; Synonyms=BAL3;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAR12_HUMAN             Reviewed;         701 AA.
AC   Q9H0J9; Q9H610; Q9NP36; Q9NTI3;
DE   RecName: Full=Poly [ADP-ribose] polymerase 12;
DE            Short=PARP-12;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 12;
DE            Short=ARTD12;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 1;
GN   Name=PARP12; Synonyms=ZC3HDC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   PAR16_HUMAN             Reviewed;         322 AA.
AC   Q8N5Y8; Q6PK64; Q9NX03;
DE   RecName: Full=Mono [ADP-ribose] polymerase PARP16;
DE            EC=2.4.2.31;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 15;
DE            Short=ARTD15;
DE   AltName: Full=Poly [ADP-ribose] polymerase 16;
DE            Short=PARP-16;
GN   Name=PARP16; Synonyms=C15orf30;
DR   GO; GO:0019900; F:kinase binding; IPI:UniProt.
DR   GO; GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IMP:UniProt.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IMP:UniProt.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProt.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:UniProt.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:UniProt.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IMP:UniProt.
DR   GO; GO:0070213; P:protein auto-ADP-ribosylation; IMP:UniProt.
//
ID   PAR1_HUMAN              Reviewed;         425 AA.
AC   P25116; Q53XV0; Q96RF7; Q9BUN4;
DE   RecName: Full=Proteinase-activated receptor 1;
DE            Short=PAR-1;
DE   AltName: Full=Coagulation factor II receptor;
DE   AltName: Full=Thrombin receptor;
DE   Flags: Precursor;
GN   Name=F2R; Synonyms=CF2R, PAR1, TR;
DR   GuidetoPHARMACOLOGY; 347; -.
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; ISS:UniProtKB.
DR   GO; GO:0031681; F:G-protein beta-subunit binding; ISS:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0015057; F:thrombin receptor activity; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0000186; P:activation of MAPKK activity; ISS:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0002248; P:connective tissue replacement involved in inflammatory response wound healing; IDA:BHF-UCL.
DR   GO; GO:0007529; P:establishment of synaptic specificity at neuromuscular junction; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:1900134; P:negative regulation of renin secretion into blood stream; ISS:UniProtKB.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; IDA:BHF-UCL.
DR   GO; GO:0060155; P:platelet dense granule organization; IC:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:UniProtKB.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; ISS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:2000778; P:positive regulation of interleukin-6 secretion; IDA:UniProtKB.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IDA:UniProtKB.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; ISS:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030193; P:regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0032651; P:regulation of interleukin-1 beta production; ISS:UniProtKB.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; IDA:BHF-UCL.
DR   GO; GO:0007262; P:STAT protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0007260; P:tyrosine phosphorylation of STAT protein; IDA:BHF-UCL.
//
ID   PAR3L_HUMAN             Reviewed;        1205 AA.
AC   Q8TEW8; E9PE87; Q8IUC7; Q8IUC9; Q96DK9; Q96N09; Q96NX6; Q96NX7;
AC   Q96Q29;
DE   RecName: Full=Partitioning defective 3 homolog B;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein;
DE   AltName: Full=PAR3-beta;
DE   AltName: Full=Partitioning defective 3-like protein;
DE            Short=PAR3-L protein;
GN   Name=PARD3B; Synonyms=ALS2CR19, PAR3B, PAR3L;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   PAR3_HUMAN              Reviewed;         374 AA.
AC   O00254; B2R754; B4DQ13; Q52M68; Q7Z3W3;
DE   RecName: Full=Proteinase-activated receptor 3;
DE            Short=PAR-3;
DE   AltName: Full=Coagulation factor II receptor-like 2;
DE   AltName: Full=Thrombin receptor-like 2;
DE   Flags: Precursor;
GN   Name=F2RL2; Synonyms=PAR3;
DR   GuidetoPHARMACOLOGY; 349; -.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015057; F:thrombin receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
//
ID   PAR4_HUMAN              Reviewed;         385 AA.
AC   Q96RI0; O76067; Q6DK42;
DE   RecName: Full=Proteinase-activated receptor 4;
DE            Short=PAR-4;
DE   AltName: Full=Coagulation factor II receptor-like 3;
DE   AltName: Full=Thrombin receptor-like 3;
DE   Flags: Precursor;
GN   Name=F2RL3; Synonyms=PAR4;
DR   GuidetoPHARMACOLOGY; 350; -.
DR   GO; GO:0015057; F:thrombin receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0060155; P:platelet dense granule organization; IC:BHF-UCL.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PAR2_HUMAN              Reviewed;         397 AA.
AC   P55085; Q13317; Q13346; Q53XJ8;
DE   RecName: Full=Proteinase-activated receptor 2;
DE            Short=PAR-2;
DE   AltName: Full=Coagulation factor II receptor-like 1;
DE   AltName: Full=G-protein coupled receptor 11;
DE   AltName: Full=Thrombin receptor-like 1;
DE   Contains:
DE     RecName: Full=Proteinase-activated receptor 2, alternate cleaved 1;
DE   Contains:
DE     RecName: Full=Proteinase-activated receptor 2, alternate cleaved 2;
DE   Flags: Precursor;
GN   Name=F2RL1; Synonyms=GPR11, PAR2;
DR   GuidetoPHARMACOLOGY; 348; -.
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; ISS:UniProtKB.
DR   GO; GO:0031681; F:G-protein beta-subunit binding; ISS:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0015057; F:thrombin receptor activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:InterPro.
DR   GO; GO:0035926; P:chemokine (C-C motif) ligand 2 secretion; IDA:UniProtKB.
DR   GO; GO:0090195; P:chemokine secretion; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0072643; P:interferon-gamma secretion; ISS:UniProtKB.
DR   GO; GO:0050702; P:interleukin-1 beta secretion; IDA:UniProtKB.
DR   GO; GO:0072608; P:interleukin-10 secretion; IDA:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; IDA:UniProtKB.
DR   GO; GO:0070661; P:leukocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0097029; P:mature dendritic cell differentiation; IDA:UniProtKB.
DR   GO; GO:0090198; P:negative regulation of chemokine secretion; IDA:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0034140; P:negative regulation of toll-like receptor 3 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042119; P:neutrophil activation; IDA:UniProtKB.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; ISS:UniProtKB.
DR   GO; GO:0002741; P:positive regulation of cytokine secretion involved in immune response; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0043311; P:positive regulation of eosinophil degranulation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0003104; P:positive regulation of glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:2000778; P:positive regulation of interleukin-6 secretion; IDA:UniProtKB.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0070963; P:positive regulation of neutrophil mediated killing of gram-negative bacterium; IDA:UniProtKB.
DR   GO; GO:0060100; P:positive regulation of phagocytosis, engulfment; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0031274; P:positive regulation of pseudopodium assembly; ISS:UniProtKB.
DR   GO; GO:1900135; P:positive regulation of renin secretion into blood stream; ISS:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; IDA:UniProtKB.
DR   GO; GO:0034137; P:positive regulation of toll-like receptor 2 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034141; P:positive regulation of toll-like receptor 3 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; ISS:UniProtKB.
DR   GO; GO:0030193; P:regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0002286; P:T cell activation involved in immune response; ISS:UniProtKB.
//
ID   PAR6A_HUMAN             Reviewed;         346 AA.
AC   Q9NPB6; O14911; Q9NPJ7;
DE   RecName: Full=Partitioning defective 6 homolog alpha;
DE            Short=PAR-6;
DE            Short=PAR-6 alpha;
DE            Short=PAR-6A;
DE   AltName: Full=PAR6C;
DE   AltName: Full=Tax interaction protein 40;
DE            Short=TIP-40;
GN   Name=PARD6A; Synonyms=PAR6A;
DR   GO; GO:0030742; F:GTP-dependent protein binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017048; F:Rho GTPase binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045217; P:cell-cell junction maintenance; ISS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:ProtInc.
//
ID   PAR6B_HUMAN             Reviewed;         372 AA.
AC   Q9BYG5; A2A2A7; Q9Y510;
DE   RecName: Full=Partitioning defective 6 homolog beta;
DE            Short=PAR-6 beta;
DE            Short=PAR-6B;
GN   Name=PARD6B; Synonyms=PAR6B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; TAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; TAS:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   PAR6G_HUMAN             Reviewed;         376 AA.
AC   Q9BYG4; A8QM57;
DE   RecName: Full=Partitioning defective 6 homolog gamma;
DE            Short=PAR-6 gamma;
DE   AltName: Full=PAR6D;
GN   Name=PARD6G; Synonyms=PAR6G;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0070830; P:tight junction assembly; TAS:Reactome.
//
ID   PARD3_HUMAN             Reviewed;        1356 AA.
AC   Q8TEW0; F5H5T0; Q5T2U1; Q5VUA2; Q5VUA3; Q5VWV0; Q5VWV1; Q5VWV3;
AC   Q5VWV4; Q5VWV5; Q6IQ47; Q8TCZ9; Q8TEW1; Q8TEW2; Q8TEW3; Q96K28;
AC   Q96RM6; Q96RM7; Q9BY57; Q9BY58; Q9HC48; Q9NWL4; Q9NYE6;
DE   RecName: Full=Partitioning defective 3 homolog;
DE            Short=PAR-3;
DE            Short=PARD-3;
DE   AltName: Full=Atypical PKC isotype-specific-interacting protein;
DE            Short=ASIP;
DE   AltName: Full=CTCL tumor antigen se2-5;
DE   AltName: Full=PAR3-alpha;
GN   Name=PARD3; Synonyms=PAR3, PAR3A;
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003383; P:apical constriction; IEA:Ensembl.
DR   GO; GO:0008356; P:asymmetric cell division; TAS:ProtInc.
DR   GO; GO:0007409; P:axonogenesis; TAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; ISS:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
DR   GO; GO:0032970; P:regulation of actin filament-based process; IEA:Ensembl.
DR   GO; GO:0060341; P:regulation of cellular localization; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; ISS:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0044319; P:wound healing, spreading of cells; IEA:Ensembl.
//
ID   PARG_HUMAN              Reviewed;         976 AA.
AC   Q86W56; A5YBK3; B2RC24; B4DIU5; B4DYR4; I6RUV3; Q6E4P6; Q6E4P7;
AC   Q7Z742; Q9Y4W7;
DE   RecName: Full=Poly(ADP-ribose) glycohydrolase;
DE            EC=3.2.1.143;
GN   Name=PARG;
DR   GO; GO:0004649; F:poly(ADP-ribose) glycohydrolase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0016045; P:detection of bacterium; IEA:Ensembl.
//
ID   PARI_HUMAN              Reviewed;         579 AA.
AC   Q9NWS1; B4E0Y0; Q05C00; Q499L8; Q4FZA0; Q4KMW7; Q6NSC6; Q6PJA1;
AC   Q86W36;
DE   RecName: Full=PCNA-interacting partner;
DE            Short=PARI;
DE   AltName: Full=PARP-1 binding protein;
DE   AltName: Full=PARP1-binding protein;
DE            Short=PARPBP;
GN   Name=PARPBP; Synonyms=C12orf48, PARI;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:2000042; P:negative regulation of double-strand break repair via homologous recombination; IMP:UniProtKB.
//
ID   PARK7_HUMAN             Reviewed;         189 AA.
AC   Q99497; B2R4Z1; O14805; Q6DR95; Q7LFU2;
DE   RecName: Full=Protein DJ-1;
DE            EC=3.4.-.-;
DE   AltName: Full=Oncogene DJ1;
DE   AltName: Full=Parkinson disease protein 7;
DE   Flags: Precursor;
GN   Name=PARK7;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:ParkinsonsUK-UCL.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; ISS:UniProtKB.
DR   GO; GO:0051920; F:peroxiredoxin activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0051583; P:dopamine uptake involved in synaptic transmission; IEA:Ensembl.
DR   GO; GO:0042743; P:hydrogen peroxide metabolic process; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0051899; P:membrane depolarization; IEA:Ensembl.
DR   GO; GO:0060081; P:membrane hyperpolarization; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:GOC.
DR   GO; GO:2000825; P:positive regulation of androgen receptor activity; IMP:ParkinsonsUK-UCL.
DR   GO; GO:2000277; P:positive regulation of oxidative phosphorylation uncoupler activity; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
//
ID   PARL_HUMAN              Reviewed;         379 AA.
AC   Q9H300; Q96CQ4; Q9BTJ6; Q9P1E3;
DE   RecName: Full=Presenilins-associated rhomboid-like protein, mitochondrial;
DE            EC=3.4.21.105;
DE   AltName: Full=Mitochondrial intramembrane cleaving protease PARL;
DE   Contains:
DE     RecName: Full=P-beta;
DE              Short=Pbeta;
DE   Flags: Precursor;
GN   Name=PARL; Synonyms=PSARL; ORFNames=PRO2207;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
//
ID   PARM1_HUMAN             Reviewed;         310 AA.
AC   Q6UWI2; B3KMQ9; Q96DV8; Q9Y4S1;
DE   RecName: Full=Prostate androgen-regulated mucin-like protein 1;
DE            Short=PARM-1;
DE   Flags: Precursor;
GN   Name=PARM1; ORFNames=UNQ1879/PRO4322;
DR   GO; GO:0051973; P:positive regulation of telomerase activity; ISS:UniProtKB.
//
ID   PARN_HUMAN              Reviewed;         639 AA.
AC   O95453; B2RCB3; B4DDG8; B4DWR4; B4E1H6;
DE   RecName: Full=Poly(A)-specific ribonuclease PARN;
DE            EC=3.1.13.4;
DE   AltName: Full=Deadenylating nuclease;
DE   AltName: Full=Deadenylation nuclease;
DE   AltName: Full=Polyadenylate-specific ribonuclease;
GN   Name=PARN; Synonyms=DAN;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; TAS:ProtInc.
DR   GO; GO:0004518; F:nuclease activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0009451; P:RNA modification; TAS:ProtInc.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; TAS:GOC.
//
ID   PARP1_HUMAN             Reviewed;        1014 AA.
AC   P09874; B1ANJ4; Q8IUZ9;
DE   RecName: Full=Poly [ADP-ribose] polymerase 1;
DE            Short=PARP-1;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 1;
DE            Short=ARTD1;
DE   AltName: Full=NAD(+) ADP-ribosyltransferase 1;
DE            Short=ADPRT 1;
DE   AltName: Full=Poly[ADP-ribose] synthase 1;
GN   Name=PARP1; Synonyms=ADPRT, PPOL;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0051287; F:NAD binding; IEA:Ensembl.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030225; P:macrophage differentiation; TAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0016540; P:protein autoprocessing; IEA:Ensembl.
DR   GO; GO:0070212; P:protein poly-ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0040009; P:regulation of growth rate; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   PARP2_HUMAN             Reviewed;         583 AA.
AC   Q9UGN5; Q8TEU4; Q9NUV2; Q9UMR4; Q9Y6C8;
DE   RecName: Full=Poly [ADP-ribose] polymerase 2;
DE            Short=PARP-2;
DE            Short=hPARP-2;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 2;
DE            Short=ARTD2;
DE   AltName: Full=NAD(+) ADP-ribosyltransferase 2;
DE            Short=ADPRT-2;
DE   AltName: Full=Poly[ADP-ribose] synthase 2;
DE            Short=pADPRT-2;
GN   Name=PARP2; Synonyms=ADPRT2, ADPRTL2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006284; P:base-excision repair; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.
//
ID   PARP3_HUMAN             Reviewed;         533 AA.
AC   Q9Y6F1; Q8NER9; Q96CG2; Q9UG81;
DE   RecName: Full=Poly [ADP-ribose] polymerase 3;
DE            Short=PARP-3;
DE            Short=hPARP-3;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 3;
DE            Short=ARTD3;
DE   AltName: Full=IRT1;
DE   AltName: Full=NAD(+) ADP-ribosyltransferase 3;
DE            Short=ADPRT-3;
DE   AltName: Full=Poly[ADP-ribose] synthase 3;
DE            Short=pADPRT-3;
GN   Name=PARP3; Synonyms=ADPRT3, ADPRTL3;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:MGI.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006302; P:double-strand break repair; IDA:MGI.
DR   GO; GO:0051106; P:positive regulation of DNA ligation; IGI:MGI.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IDA:MGI.
DR   GO; GO:1990166; P:protein localization to site of double-strand break; IMP:MGI.
DR   GO; GO:0060236; P:regulation of mitotic spindle organization; IMP:MGI.
DR   GO; GO:0000723; P:telomere maintenance; IMP:MGI.
//
ID   PARP4_HUMAN             Reviewed;        1724 AA.
AC   Q9UKK3; O75903; Q14682; Q5QNZ9; Q9H1M6;
DE   RecName: Full=Poly [ADP-ribose] polymerase 4;
DE            Short=PARP-4;
DE            EC=2.4.2.30;
DE   AltName: Full=193 kDa vault protein;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 4;
DE            Short=ARTD4;
DE   AltName: Full=PARP-related/IalphaI-related H5/proline-rich;
DE            Short=PH5P;
DE   AltName: Full=Vault poly(ADP-ribose) polymerase;
DE            Short=VPARP;
GN   Name=PARP4; Synonyms=ADPRTL1, KIAA0177, PARPL;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IDA:MGI.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IMP:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; NAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IMP:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; NAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   PARP6_HUMAN             Reviewed;         630 AA.
AC   Q2NL67; Q9H7C5; Q9H9X6; Q9HAF3; Q9NPS6; Q9UFG4;
DE   RecName: Full=Poly [ADP-ribose] polymerase 6;
DE            Short=PARP-6;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 17;
DE            Short=ARTD17;
GN   Name=PARP6;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
//
ID   PARP8_HUMAN             Reviewed;         854 AA.
AC   Q8N3A8; Q3KRB7; Q6DHZ1; Q9H754;
DE   RecName: Full=Poly [ADP-ribose] polymerase 8;
DE            Short=PARP-8;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16;
DE            Short=ARTD16;
GN   Name=PARP8;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-EC.
//
ID   PARP9_HUMAN             Reviewed;         854 AA.
AC   Q8IXQ6; A8KA94; B2R8S9; E9PFM7; Q8TCP3; Q9BZL8; Q9BZL9;
DE   RecName: Full=Poly [ADP-ribose] polymerase 9;
DE            Short=PARP-9;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 9;
DE            Short=ARTD9;
DE   AltName: Full=B aggressive lymphoma protein;
GN   Name=PARP9; Synonyms=BAL, BAL1;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0060330; P:regulation of response to interferon-gamma; IDA:UniProtKB.
//
ID   PARPT_HUMAN             Reviewed;         657 AA.
AC   Q7Z3E1; D3DNK6; Q68CY9; Q86VP4; Q9Y4P7;
DE   RecName: Full=TCDD-inducible poly [ADP-ribose] polymerase;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 14;
DE            Short=ARTD14;
DE   AltName: Full=Poly [ADP-ribose] polymerase 7;
DE            Short=PARP-7;
GN   Name=TIPARP; Synonyms=PARP7;
DR   GO; GO:0035326; F:enhancer binding; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:MGI.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.
DR   GO; GO:0008210; P:estrogen metabolic process; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0044236; P:multicellular organismal metabolic process; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:MGI.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IMP:MGI.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   PARVA_HUMAN             Reviewed;         372 AA.
AC   Q9NVD7; Q96C85; Q9HA48;
DE   RecName: Full=Alpha-parvin;
DE   AltName: Full=Actopaxin;
DE   AltName: Full=CH-ILKBP;
DE   AltName: Full=Calponin-like integrin-linked kinase-binding protein;
DE   AltName: Full=Matrix-remodeling-associated protein 2;
GN   Name=PARVA; Synonyms=MXRA2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:InterPro.
DR   GO; GO:0070252; P:actin-mediated cell contraction; ISS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0071670; P:smooth muscle cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
//
ID   PARVB_HUMAN             Reviewed;         364 AA.
AC   Q9HBI1; B0QYM8; B0QYN1; B2R9X6; Q5TGJ5; Q86X93; Q96PN1; Q9NSP7;
AC   Q9UGT3; Q9Y368; Q9Y3L6; Q9Y3L7;
DE   RecName: Full=Beta-parvin;
DE   AltName: Full=Affixin;
GN   Name=PARVB; ORFNames=CGI-56;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0030031; P:cell projection assembly; IMP:UniProtKB.
DR   GO; GO:0071963; P:establishment or maintenance of cell polarity regulating cell shape; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.
//
ID   PARVG_HUMAN             Reviewed;         331 AA.
AC   Q9HBI0; B4DDW5; E7EVM6; Q9BQX5; Q9NSG1;
DE   RecName: Full=Gamma-parvin;
GN   Name=PARVG;
DR   GO; GO:0003779; F:actin binding; TAS:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:InterPro.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:UniProtKB.
//
ID   PASK_HUMAN              Reviewed;        1323 AA.
AC   Q96RG2; G5E9F1; Q05BE4; Q68DY3; Q6GSJ5; Q86XH6; Q99763; Q9UFR7;
DE   RecName: Full=PAS domain-containing serine/threonine-protein kinase;
DE            Short=PAS-kinase;
DE            Short=PASKIN;
DE            Short=hPASK;
DE            EC=2.7.11.1;
GN   Name=PASK; Synonyms=KIAA0135;
DR   GuidetoPHARMACOLOGY; 2139; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; TAS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0070092; P:regulation of glucagon secretion; ISS:UniProtKB.
DR   GO; GO:0043576; P:regulation of respiratory gaseous exchange; ISS:UniProtKB.
//
ID   PASD1_HUMAN             Reviewed;         773 AA.
AC   Q8IV76; Q3MNE0; Q69HD7; Q8N7X9;
DE   RecName: Full=PAS domain-containing protein 1;
DE   AltName: Full=Cancer/testis antigen 63;
DE            Short=CT63;
DE   AltName: Full=OX-TES-1;
GN   Name=PASD1;
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
//
ID   PATE1_HUMAN             Reviewed;         126 AA.
AC   Q8WXA2; Q3KNX2;
DE   RecName: Full=Prostate and testis expressed protein 1;
DE   Flags: Precursor;
GN   Name=PATE1; Synonyms=PATE;
//
ID   PATE2_HUMAN             Reviewed;         113 AA.
AC   Q6UY27; B2RNZ2; B7ZMG4;
DE   RecName: Full=Prostate and testis expressed protein 2;
DE   AltName: Full=PATE-like protein M;
DE            Short=PATE-M;
DE   Flags: Precursor;
GN   Name=PATE2; Synonyms=C11orf38; ORFNames=UNQ3112/PRO10144;
//
ID   PATE4_HUMAN             Reviewed;          98 AA.
AC   P0C8F1;
DE   RecName: Full=Prostate and testis expressed protein 4;
DE   AltName: Full=PATE-like protein B;
DE            Short=PATE-B;
DE   Flags: Precursor;
GN   Name=PATE4;
DR   GO; GO:0050804; P:regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
//
ID   PATE3_HUMAN             Reviewed;          98 AA.
AC   B3GLJ2; B5KFZ3;
DE   RecName: Full=Prostate and testis expressed protein 3;
DE   AltName: Full=Acrosomal vesicle protein HEL-127;
DE   AltName: Full=PATE-like protein DJ;
DE            Short=PATE-DJ;
DE   Flags: Precursor;
GN   Name=PATE3;
//
ID   PATL1_HUMAN             Reviewed;         770 AA.
AC   Q86TB9; B3KXT9; Q2TA86; Q6P166; Q8N9M6; Q8NI63;
DE   RecName: Full=Protein PAT1 homolog 1;
DE   AltName: Full=PAT1-like protein 1;
DE   AltName: Full=Protein PAT1 homolog b;
DE            Short=Pat1b;
DE            Short=hPat1b;
GN   Name=PATL1; ORFNames=OK/KNS-cl.5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0034046; F:poly(G) binding; IDA:MGI.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; IDA:UniProtKB.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IDA:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   PATL2_HUMAN             Reviewed;         543 AA.
AC   C9JE40;
DE   RecName: Full=Protein PAT1 homolog 2;
DE   AltName: Full=PAT1-like protein 2;
DE   AltName: Full=Protein PAT1 homolog a;
DE            Short=Pat1a;
DE            Short=hPat1a;
GN   Name=PATL2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0010607; P:negative regulation of cytoplasmic mRNA processing body assembly; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; ISS:UniProtKB.
//
ID   PATZ1_HUMAN             Reviewed;         687 AA.
AC   Q9HBE1; Q9HBE2; Q9HBE3; Q9P1A9; Q9UDU0; Q9Y529;
DE   RecName: Full=POZ-, AT hook-, and zinc finger-containing protein 1;
DE   AltName: Full=BTB/POZ domain zinc finger transcription factor;
DE   AltName: Full=Protein kinase A RI subunit alpha-associated protein;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 19;
DE   AltName: Full=Zinc finger protein 278;
DE   AltName: Full=Zinc finger sarcoma gene protein;
GN   Name=PATZ1; Synonyms=PATZ, RIAZ, ZBTB19, ZNF278, ZSG;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAWR_HUMAN              Reviewed;         340 AA.
AC   Q96IZ0; O75796; Q6FHY9; Q8N700;
DE   RecName: Full=PRKC apoptosis WT1 regulator protein;
DE   AltName: Full=Prostate apoptosis response 4 protein;
DE            Short=Par-4;
GN   Name=PAWR; Synonyms=PAR4;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IDA:UniProtKB.
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0042094; P:interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0042986; P:positive regulation of amyloid precursor protein biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAX1_HUMAN              Reviewed;         534 AA.
AC   P15863; B4E0D6; Q642X9; Q6NTC0; Q9Y558;
DE   RecName: Full=Paired box protein Pax-1;
DE   AltName: Full=HuP48;
GN   Name=PAX1; Synonyms=HUP48;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0043367; P:CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043374; P:CD8-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0060017; P:parathyroid gland development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0061056; P:sclerotome development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PAX3_HUMAN              Reviewed;         479 AA.
AC   P23760; G5E9C1; Q16448; Q494Z3; Q494Z4; Q53T90; Q6GSJ9; Q86UQ2;
AC   Q86UQ3;
DE   RecName: Full=Paired box protein Pax-3;
DE   AltName: Full=HuP2;
GN   Name=PAX3; Synonyms=HUP2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0060594; P:mammary gland specification; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0014807; P:regulation of somitogenesis; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PAX2_HUMAN              Reviewed;         417 AA.
AC   Q02962; Q15105; Q15110; Q15837; Q5SZP2; Q5SZP3;
DE   RecName: Full=Paired box protein Pax-2;
GN   Name=PAX2;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016175; F:superoxide-generating NADPH oxidase activity; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; TAS:ProtInc.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; ISS:UniProtKB.
DR   GO; GO:0001709; P:cell fate determination; ISS:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; ISS:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0090102; P:cochlea development; ISS:UniProtKB.
DR   GO; GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010001; P:glial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007501; P:mesodermal cell fate specification; ISS:UniProtKB.
DR   GO; GO:0072177; P:mesonephric duct development; IEA:Ensembl.
DR   GO; GO:0072172; P:mesonephric tubule formation; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; ISS:UniProtKB.
DR   GO; GO:0072205; P:metanephric collecting duct development; ISS:UniProtKB.
DR   GO; GO:0072221; P:metanephric distal convoluted tubule development; ISS:UniProtKB.
DR   GO; GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.
DR   GO; GO:0072162; P:metanephric mesenchymal cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:1900215; P:negative regulation of apoptotic process involved in metanephric collecting duct development; ISS:UniProtKB.
DR   GO; GO:1900218; P:negative regulation of apoptotic process involved in metanephric nephron tubule development; ISS:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045918; P:negative regulation of cytolysis; IMP:UniProtKB.
DR   GO; GO:0072305; P:negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis; ISS:UniProtKB.
DR   GO; GO:1900212; P:negative regulation of mesenchymal cell apoptotic process involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; ISS:UniProtKB.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0072179; P:nephric duct formation; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0061360; P:optic chiasma development; ISS:UniProtKB.
DR   GO; GO:0002072; P:optic cup morphogenesis involved in camera-type eye development; ISS:UniProtKB.
DR   GO; GO:0021554; P:optic nerve development; ISS:UniProtKB.
DR   GO; GO:0021631; P:optic nerve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021633; P:optic nerve structural organization; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:GOC.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0061205; P:paramesonephric duct development; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0072108; P:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; ISS:UniProtKB.
DR   GO; GO:2000594; P:positive regulation of metanephric DCT cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072300; P:positive regulation of metanephric glomerulus development; ISS:UniProtKB.
DR   GO; GO:2000597; P:positive regulation of optic nerve formation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0039003; P:pronephric field specification; ISS:UniProtKB.
DR   GO; GO:0048793; P:pronephros development; ISS:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; ISS:UniProtKB.
DR   GO; GO:0072307; P:regulation of metanephric nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0035566; P:regulation of metanephros size; IMP:UniProtKB.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0003406; P:retinal pigment epithelium development; ISS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0072189; P:ureter development; ISS:UniProtKB.
DR   GO; GO:0035799; P:ureter maturation; ISS:UniProtKB.
DR   GO; GO:0072197; P:ureter morphogenesis; IEA:Ensembl.
DR   GO; GO:0001655; P:urogenital system development; ISS:UniProtKB.
DR   GO; GO:0021650; P:vestibulocochlear nerve formation; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PAX5_HUMAN              Reviewed;         391 AA.
AC   Q02548; A3QVP6; A3QVP7; A3QVP8; C0KTF6; C0KTF7; C0KTF8; C0KTF9;
AC   C0KTG0; O75933; Q5SFM2; Q6S728; Q6S729; Q6S730; Q6S731; Q6S732;
DE   RecName: Full=Paired box protein Pax-5;
DE   AltName: Full=B-cell-specific transcription factor;
DE            Short=BSAP;
GN   Name=PAX5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0051573; P:negative regulation of histone H3-K9 methylation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PAX4_HUMAN              Reviewed;         350 AA.
AC   O43316; O95161; Q6B0H0;
DE   RecName: Full=Paired box protein Pax-4;
GN   Name=PAX4;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAX6_HUMAN              Reviewed;         422 AA.
AC   P26367; Q6N006; Q99413;
DE   RecName: Full=Paired box protein Pax-6;
DE   AltName: Full=Aniridia type II protein;
DE   AltName: Full=Oculorhombin;
GN   Name=PAX6; Synonyms=AN2;
DR   GO; GO:0003680; F:AT DNA binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0035035; F:histone acetyltransferase binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; ISS:BHF-UCL.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0048708; P:astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IMP:DFLAT.
DR   GO; GO:0001709; P:cell fate determination; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR   GO; GO:0021902; P:commitment of neuronal cell to specific neuron type in forebrain; IEA:Ensembl.
DR   GO; GO:0061303; P:cornea development in camera-type eye; IMP:DFLAT.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; TAS:ProtInc.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0021798; P:forebrain dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0021905; P:forebrain-midbrain boundary formation; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:DFLAT.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0061072; P:iris morphogenesis; IMP:DFLAT.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032808; P:lacrimal gland development; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; NAS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0021778; P:oligodendrocyte cell fate specification; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0003322; P:pancreatic A cell development; IMP:BHF-UCL.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0042660; P:positive regulation of cell fate specification; IEA:Ensembl.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:GOC.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0048505; P:regulation of timing of cell differentiation; IEA:Ensembl.
DR   GO; GO:0021918; P:regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0021912; P:regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification; IEA:Ensembl.
DR   GO; GO:0021913; P:regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEP:UniProtKB.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0003309; P:type B pancreatic cell differentiation; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PAX7_HUMAN              Reviewed;         520 AA.
AC   P23759; E9PFV9; Q0VA99; Q2PJS5;
DE   RecName: Full=Paired box protein Pax-7;
DE   AltName: Full=HuP1;
GN   Name=PAX7; Synonyms=HUP1;
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0060415; P:muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0031062; P:positive regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:2000288; P:positive regulation of myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010453; P:regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0014813; P:satellite cell commitment; IEA:Ensembl.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
//
ID   PAX9_HUMAN              Reviewed;         341 AA.
AC   P55771; Q99582; Q9UQR4;
DE   RecName: Full=Paired box protein Pax-9;
GN   Name=PAX9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0042481; P:regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAX8_HUMAN              Reviewed;         450 AA.
AC   Q06710; Q09155; Q16337; Q16338; Q16339; Q4ZG35; Q96J49;
DE   RecName: Full=Paired box protein Pax-8;
GN   Name=PAX8;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0004996; F:thyroid-stimulating hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IEP:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEP:UniProtKB.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEP:UniProtKB.
DR   GO; GO:0072164; P:mesonephric tubule development; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; ISS:UniProtKB.
DR   GO; GO:0072278; P:metanephric comma-shaped body morphogenesis; IEP:UniProtKB.
DR   GO; GO:0072221; P:metanephric distal convoluted tubule development; ISS:UniProtKB.
DR   GO; GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.
DR   GO; GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.
DR   GO; GO:0072284; P:metanephric S-shaped body morphogenesis; IEP:UniProtKB.
DR   GO; GO:1900215; P:negative regulation of apoptotic process involved in metanephric collecting duct development; ISS:UniProtKB.
DR   GO; GO:1900218; P:negative regulation of apoptotic process involved in metanephric nephron tubule development; ISS:UniProtKB.
DR   GO; GO:0072305; P:negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis; ISS:UniProtKB.
DR   GO; GO:1900212; P:negative regulation of mesenchymal cell apoptotic process involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0071599; P:otic vesicle development; IEP:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072108; P:positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; ISS:UniProtKB.
DR   GO; GO:2000594; P:positive regulation of metanephric DCT cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000611; P:positive regulation of thyroid hormone generation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0039003; P:pronephric field specification; ISS:UniProtKB.
DR   GO; GO:0048793; P:pronephros development; ISS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0072307; P:regulation of metanephric nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000612; P:regulation of thyroid-stimulating hormone secretion; IMP:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IMP:UniProtKB.
DR   GO; GO:0038194; P:thyroid-stimulating hormone signaling pathway; TAS:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001655; P:urogenital system development; ISS:UniProtKB.
//
ID   PAXB1_HUMAN             Reviewed;         917 AA.
AC   Q9Y5B6; D3DSE7; Q96DU8; Q9NYQ0;
DE   RecName: Full=PAX3- and PAX7-binding protein 1;
DE   AltName: Full=GC-rich sequence DNA-binding factor 1;
GN   Name=PAXBP1; Synonyms=C21orf66, GCFC, GCFC1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0031062; P:positive regulation of histone methylation; IEA:Ensembl.
DR   GO; GO:2000288; P:positive regulation of myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0014842; P:regulation of satellite cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PAXI1_HUMAN             Reviewed;        1069 AA.
AC   Q6ZW49; O15404; Q6N099; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2;
DE   RecName: Full=PAX-interacting protein 1;
DE   AltName: Full=PAX transactivation activation domain-interacting protein;
GN   Name=PAXIP1; Synonyms=PAXIP1L, PTIP; ORFNames=CAGF28;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0060717; P:chorion development; IEA:Ensembl.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043542; P:endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; ISS:UniProtKB.
DR   GO; GO:0000416; P:positive regulation of histone H3-K36 methylation; ISS:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.
DR   GO; GO:0045830; P:positive regulation of isotype switching; ISS:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   PAXI_HUMAN              Reviewed;         591 AA.
AC   P49023; B2RAI3; B7ZMB4; O14970; O14971; O60360; Q5HYA4;
DE   RecName: Full=Paxillin;
GN   Name=PXN;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IEP:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0007172; P:signal complex assembly; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PB1_HUMAN               Reviewed;        1689 AA.
AC   Q86U86; A1L381; A1L382; A4FUJ7; Q1RMD1; Q1RMD2; Q96MS2; Q9H2T3;
AC   Q9H2T4; Q9H2T5; Q9H301; Q9H314;
DE   RecName: Full=Protein polybromo-1;
DE            Short=hPB1;
DE   AltName: Full=BRG1-associated factor 180;
DE            Short=BAF180;
DE   AltName: Full=Polybromo-1D;
GN   Name=PBRM1; Synonyms=BAF180, PB1;
DR   GO; GO:0003682; F:chromatin binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PBDC1_HUMAN             Reviewed;         233 AA.
AC   Q9BVG4;
DE   RecName: Full=Protein PBDC1;
DE   AltName: Full=Polysaccharide biosynthesis domain-containing protein 1;
GN   Name=PBDC1; Synonyms=CXorf26;
//
ID   PBIP1_HUMAN             Reviewed;         731 AA.
AC   Q96AQ6; Q5T174; Q5T176; Q9H8X6; Q9HA02; Q9HD85;
DE   RecName: Full=Pre-B-cell leukemia transcription factor-interacting protein 1;
DE   AltName: Full=Hematopoietic PBX-interacting protein;
GN   Name=PBXIP1; Synonyms=HPIP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   PBMU2_HUMAN             Reviewed;         251 AA.
AC   E2RYF7;
DE   RecName: Full=Protein PBMUCL2;
DE   AltName: Full=HLA complex group 22;
DE   AltName: Full=Panbronchiolitis-related mucin-like protein 2;
DE   Flags: Precursor;
GN   Name=HCG22; Synonyms=G2, PBMUCL2;
//
ID   PBLD_HUMAN              Reviewed;         288 AA.
AC   P30039; A8MZJ3; C9JIM0; Q9HCC2;
DE   RecName: Full=Phenazine biosynthesis-like domain-containing protein;
DE            EC=5.1.-.-;
DE   AltName: Full=MAWD-binding protein;
DE            Short=MAWDBP;
DE   AltName: Full=Unknown protein 32 from 2D-page of liver tissue;
GN   Name=PBLD; Synonyms=MAWBP;
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProt.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IMP:UniProt.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:UniProt.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:UniProt.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IMP:UniProt.
DR   GO; GO:0060392; P:negative regulation of SMAD protein import into nucleus; IGI:UniProt.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:UniProt.
//
ID   PBOV1_HUMAN             Reviewed;         135 AA.
AC   Q9GZY1;
DE   RecName: Full=Prostate and breast cancer overexpressed gene 1 protein;
DE   AltName: Full=Protein UROC28;
DE            Short=UC28;
GN   Name=PBOV1; Synonyms=UROC28;
//
ID   PBX1_HUMAN              Reviewed;         430 AA.
AC   P40424; B4DSC1; F5H4U9; Q5T488;
DE   RecName: Full=Pre-B-cell leukemia transcription factor 1;
DE   AltName: Full=Homeobox protein PBX1;
DE   AltName: Full=Homeobox protein PRL;
GN   Name=PBX1; Synonyms=PRL;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0030278; P:regulation of ossification; IEA:Ensembl.
DR   GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   PBX2_HUMAN              Reviewed;         430 AA.
AC   P40425; A2BFJ2;
DE   RecName: Full=Pre-B-cell leukemia transcription factor 2;
DE   AltName: Full=Homeobox protein PBX2;
DE   AltName: Full=Protein G17;
GN   Name=PBX2; Synonyms=G17;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PBX3_HUMAN              Reviewed;         434 AA.
AC   P40426; E9PB27; Q5JSA0; Q5JSA1; Q5VXL3; Q96PF9; Q96PG0;
DE   RecName: Full=Pre-B-cell leukemia transcription factor 3;
DE   AltName: Full=Homeobox protein PBX3;
GN   Name=PBX3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007387; P:anterior compartment pattern formation; TAS:ProtInc.
DR   GO; GO:0021516; P:dorsal spinal cord development; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0007388; P:posterior compartment specification; TAS:ProtInc.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PBX4_HUMAN              Reviewed;         374 AA.
AC   Q9BYU1; A5D8Y0; B3KUK9;
DE   RecName: Full=Pre-B-cell leukemia transcription factor 4;
DE   AltName: Full=Homeobox protein PBX4;
GN   Name=PBX4;
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IC:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IC:BHF-UCL.
//
ID   PC11X_HUMAN             Reviewed;        1347 AA.
AC   Q9BZA7; A6NIQ4; Q2TJH0; Q2TJH1; Q2TJH3; Q5JVZ0; Q70LR8; Q70LS7;
AC   Q70LS8; Q70LS9; Q70LT7; Q70LT8; Q70LT9; Q70LU0; Q70LU1; Q96RV4;
AC   Q96RW0; Q9BZA6; Q9H4E0; Q9P2M0; Q9P2X5;
DE   RecName: Full=Protocadherin-11 X-linked;
DE            Short=Protocadherin-11;
DE   AltName: Full=Protocadherin on the X chromosome;
DE            Short=PCDH-X;
DE   AltName: Full=Protocadherin-S;
DE   Flags: Precursor;
GN   Name=PCDH11X; Synonyms=KIAA1326, PCDH11, PCDHX;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PC11Y_HUMAN             Reviewed;        1340 AA.
AC   Q9BZA8; Q70LR6; Q70LR8; Q70LS0; Q70LS1; Q70LS2; Q70LS3; Q70LS4;
AC   Q70LS5; Q8WY34; Q9BZA9; Q9H4E1;
DE   RecName: Full=Protocadherin-11 Y-linked;
DE            Short=Protocadherin-11;
DE   AltName: Full=Protocadherin on the Y chromosome;
DE            Short=PCDH-Y;
DE   AltName: Full=Protocadherin prostate cancer;
DE            Short=Protocadherin-PC;
DE   AltName: Full=Protocadherin-22;
DE   Flags: Precursor;
GN   Name=PCDH11Y; Synonyms=PCDH11, PCDH22, PCDHY;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PC4L1_HUMAN             Reviewed;          68 AA.
AC   A6NKN8; B2RV24; B9EJG4;
DE   RecName: Full=Purkinje cell protein 4-like protein 1;
DE            Short=PCP4-like protein 1;
GN   Name=PCP4L1; Synonyms=IQM1;
//
ID   PCAT1_HUMAN             Reviewed;         534 AA.
AC   Q8NF37; Q1HAQ1; Q7Z4G6; Q8N3U7; Q8WUL8; Q9GZW6;
DE   RecName: Full=Lysophosphatidylcholine acyltransferase 1;
DE            Short=LPC acyltransferase 1;
DE            Short=LPCAT-1;
DE            Short=LysoPC acyltransferase 1;
DE            EC=2.3.1.23;
DE   AltName: Full=1-acylglycerophosphocholine O-acyltransferase;
DE   AltName: Full=1-alkylglycerophosphocholine O-acetyltransferase;
DE            EC=2.3.1.67;
DE   AltName: Full=Acetyl-CoA:lyso-platelet-activating factor acetyltransferase;
DE            Short=Acetyl-CoA:lyso-PAF acetyltransferase;
DE            Short=Lyso-PAF acetyltransferase;
DE            Short=LysoPAFAT;
DE   AltName: Full=Acyltransferase-like 2;
DE   AltName: Full=Phosphonoformate immuno-associated protein 3;
GN   Name=LPCAT1; Synonyms=AYTL2, PFAAP3;
DR   GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0047159; F:1-alkenylglycerophosphocholine O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0047192; F:1-alkylglycerophosphocholine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047191; F:1-alkylglycerophosphocholine O-acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:2001246; P:negative regulation of phosphatidylcholine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; IDA:UniProtKB.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   PCAT2_HUMAN             Reviewed;         544 AA.
AC   Q7L5N7; A3KBM1; Q6MZJ6; Q9NX23;
DE   RecName: Full=Lysophosphatidylcholine acyltransferase 2;
DE            Short=LPC acyltransferase 2;
DE            Short=LPCAT-2;
DE            Short=LysoPC acyltransferase 2;
DE            EC=2.3.1.23;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 11;
DE            Short=1-AGP acyltransferase 11;
DE            Short=1-AGPAT 11;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerophosphocholine O-acyltransferase;
DE   AltName: Full=1-alkylglycerophosphocholine O-acetyltransferase;
DE            EC=2.3.1.67;
DE   AltName: Full=Acetyl-CoA:lyso-platelet-activating factor acetyltransferase;
DE            Short=Acetyl-CoA:lyso-PAF acetyltransferase;
DE            Short=Lyso-PAF acetyltransferase;
DE            Short=LysoPAFAT;
DE   AltName: Full=Acyltransferase-like 1;
DE   AltName: Full=Lysophosphatidic acid acyltransferase alpha;
DE            Short=LPAAT-alpha;
GN   Name=LPCAT2; Synonyms=AGPAT11, AYTL1;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0047192; F:1-alkylglycerophosphocholine O-acetyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; ISS:UniProtKB.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006663; P:platelet activating factor biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PCBP1_HUMAN             Reviewed;         356 AA.
AC   Q15365; Q13157; Q14975;
DE   RecName: Full=Poly(rC)-binding protein 1;
DE   AltName: Full=Alpha-CP1;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein E1;
DE            Short=hnRNP E1;
DE   AltName: Full=Nucleic acid-binding protein SUB2.3;
GN   Name=PCBP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   PCBP2_HUMAN             Reviewed;         365 AA.
AC   Q15366; A8K7X6; F8VYL7; G3V0E8; I6L8F9; Q32Q82; Q59HD4; Q68Y55;
AC   Q6IPF4; Q6PKG5;
DE   RecName: Full=Poly(rC)-binding protein 2;
DE   AltName: Full=Alpha-CP2;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein E2;
DE            Short=hnRNP E2;
GN   Name=PCBP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; NAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   PCBP3_HUMAN             Reviewed;         371 AA.
AC   P57721; A8MPS2; A8MQ26; B7WNN9; B7WPC1; Q8N9K6; Q96EP6;
DE   RecName: Full=Poly(rC)-binding protein 3;
DE   AltName: Full=Alpha-CP3;
GN   Name=PCBP3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; NAS:UniProtKB.
//
ID   PCBP4_HUMAN             Reviewed;         403 AA.
AC   P57723; Q96AH7;
DE   RecName: Full=Poly(rC)-binding protein 4;
DE   AltName: Full=Alpha-CP4;
GN   Name=PCBP4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
//
ID   PCCA_HUMAN              Reviewed;         728 AA.
AC   P05165; B4DKY8; B4DPF9; C9JPQ8; Q15979; Q8WXQ7;
DE   RecName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial;
DE            Short=PCCase subunit alpha;
DE            EC=6.4.1.3;
DE   AltName: Full=Propanoyl-CoA:carbon dioxide ligase subunit alpha;
DE   Flags: Precursor;
GN   Name=PCCA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0009374; F:biotin binding; TAS:ProtInc.
DR   GO; GO:0004075; F:biotin carboxylase activity; IEA:InterPro.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004658; F:propionyl-CoA carboxylase activity; TAS:ProtInc.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PCCB_HUMAN              Reviewed;         539 AA.
AC   P05166; B7Z2Z4; Q16813; Q96CX0;
DE   RecName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial;
DE            Short=PCCase subunit beta;
DE            EC=6.4.1.3;
DE   AltName: Full=Propanoyl-CoA:carbon dioxide ligase subunit beta;
DE   Flags: Precursor;
GN   Name=PCCB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004658; F:propionyl-CoA carboxylase activity; TAS:ProtInc.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.
DR   GO; GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PCD10_HUMAN             Reviewed;        1040 AA.
AC   Q9P2E7; Q4W5F6; Q96SF0;
DE   RecName: Full=Protocadherin-10;
DE   Flags: Precursor;
GN   Name=PCDH10; Synonyms=KIAA1400;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
//
ID   PCD12_HUMAN             Reviewed;        1184 AA.
AC   Q9NPG4; Q6UXB6; Q96KB8; Q9H7Y6; Q9H8E0;
DE   RecName: Full=Protocadherin-12;
DE   AltName: Full=Vascular cadherin-2;
DE   AltName: Full=Vascular endothelial cadherin-2;
DE            Short=VE-cad-2;
DE            Short=VE-cadherin-2;
DE   Flags: Precursor;
GN   Name=PCDH12; ORFNames=UNQ395/PRO731;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0008038; P:neuron recognition; TAS:ProtInc.
//
ID   PCD15_HUMAN             Reviewed;        1955 AA.
AC   Q96QU1; A6NL19; C6ZEF5; C6ZEF6; C6ZEF7; Q5VY38; Q5VY39; Q6TRH8;
AC   Q8NDB9; Q96QT8;
DE   RecName: Full=Protocadherin-15;
DE   Flags: Precursor;
GN   Name=PCDH15; Synonyms=USH1F;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050957; P:equilibrioception; IMP:HGNC.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
//
ID   PCD16_HUMAN             Reviewed;        3298 AA.
AC   Q96JQ0; O15098;
DE   RecName: Full=Protocadherin-16;
DE   AltName: Full=Cadherin-19;
DE   AltName: Full=Cadherin-25;
DE   AltName: Full=Fibroblast cadherin-1;
DE   AltName: Full=Protein dachsous homolog 1;
DE   Flags: Precursor;
GN   Name=DCHS1; Synonyms=CDH19, CDH25, FIB1, KIAA1773, PCDH16;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
//
ID   PCD17_HUMAN             Reviewed;        1159 AA.
AC   O14917; A8K1R5; Q5VVW9; Q5VVX0;
DE   RecName: Full=Protocadherin-17;
DE   AltName: Full=Protocadherin-68;
DE   Flags: Precursor;
GN   Name=PCDH17; Synonyms=PCDH68, PCH68;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCD18_HUMAN             Reviewed;        1135 AA.
AC   Q9HCL0; A8K7K3; B7ZKT1; Q52LS2;
DE   RecName: Full=Protocadherin-18;
DE   Flags: Precursor;
GN   Name=PCDH18; Synonyms=KIAA1562;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCD19_HUMAN             Reviewed;        1148 AA.
AC   Q8TAB3; B0LDS4; E9PAM6; Q5JTG1; Q5JTG2; Q68DT7; Q9P2N3;
DE   RecName: Full=Protocadherin-19;
DE   Flags: Precursor;
GN   Name=PCDH19; Synonyms=KIAA1313;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCD20_HUMAN             Reviewed;         951 AA.
AC   Q8N6Y1; A8K1K9; B1AQU2; Q8NDN4; Q9NRT9;
DE   RecName: Full=Protocadherin-20;
DE   AltName: Full=Protocadherin-13;
DE   Flags: Precursor;
GN   Name=PCDH20; Synonyms=PCDH13;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCD23_HUMAN             Reviewed;        2916 AA.
AC   Q6V1P9; B2RU14; E9PC11; Q4W5P9; Q6ZS61; Q9NXU8;
DE   RecName: Full=Protocadherin-23;
DE   AltName: Full=Cadherin-27;
DE   AltName: Full=Cadherin-like protein CDHJ;
DE   AltName: Full=Cadherin-like protein VR8;
DE   AltName: Full=Protein dachsous homolog 2;
DE   AltName: Full=Protocadherin PCDHJ;
GN   Name=DCHS2; Synonyms=CDH27, CDHJ, PCDH23, PCDHJ;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDA1_HUMAN             Reviewed;         950 AA.
AC   Q9Y5I3; O75288; Q9NRT7;
DE   RecName: Full=Protocadherin alpha-1;
DE            Short=PCDH-alpha-1;
DE   Flags: Precursor;
GN   Name=PCDHA1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA2_HUMAN             Reviewed;         948 AA.
AC   Q9Y5H9; O75287; Q9BTV3;
DE   RecName: Full=Protocadherin alpha-2;
DE            Short=PCDH-alpha-2;
DE   Flags: Precursor;
GN   Name=PCDHA2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA3_HUMAN             Reviewed;         950 AA.
AC   Q9Y5H8; O75286;
DE   RecName: Full=Protocadherin alpha-3;
DE            Short=PCDH-alpha-3;
DE   Flags: Precursor;
GN   Name=PCDHA3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA4_HUMAN             Reviewed;         947 AA.
AC   Q9UN74; O75285; Q2M253;
DE   RecName: Full=Protocadherin alpha-4;
DE            Short=PCDH-alpha-4;
DE   Flags: Precursor;
GN   Name=PCDHA4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA5_HUMAN             Reviewed;         936 AA.
AC   Q9Y5H7; O75284; Q8N4R3;
DE   RecName: Full=Protocadherin alpha-5;
DE            Short=PCDH-alpha-5;
DE   Flags: Precursor;
GN   Name=PCDHA5; Synonyms=CNRS6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA6_HUMAN             Reviewed;         950 AA.
AC   Q9UN73; O75283; Q9NRT8;
DE   RecName: Full=Protocadherin alpha-6;
DE            Short=PCDH-alpha-6;
DE   Flags: Precursor;
GN   Name=PCDHA6; Synonyms=CNRS2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA7_HUMAN             Reviewed;         937 AA.
AC   Q9UN72; O75282;
DE   RecName: Full=Protocadherin alpha-7;
DE            Short=PCDH-alpha-7;
DE   Flags: Precursor;
GN   Name=PCDHA7; Synonyms=CNRS4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA8_HUMAN             Reviewed;         950 AA.
AC   Q9Y5H6; B9EGT7; O75281;
DE   RecName: Full=Protocadherin alpha-8;
DE            Short=PCDH-alpha-8;
DE   Flags: Precursor;
GN   Name=PCDHA8;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDA9_HUMAN             Reviewed;         950 AA.
AC   Q9Y5H5; O15053; Q2M3S5;
DE   RecName: Full=Protocadherin alpha-9;
DE            Short=PCDH-alpha-9;
DE   Flags: Precursor;
GN   Name=PCDHA9; Synonyms=KIAA0345;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDAA_HUMAN             Reviewed;         948 AA.
AC   Q9Y5I2; A1L493; O75280; Q9NRU2;
DE   RecName: Full=Protocadherin alpha-10;
DE            Short=PCDH-alpha-10;
DE   Flags: Precursor;
GN   Name=PCDHA10; Synonyms=CNRS8;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDAB_HUMAN             Reviewed;         949 AA.
AC   Q9Y5I1; B2RN58; O75279;
DE   RecName: Full=Protocadherin alpha-11;
DE            Short=PCDH-alpha-11;
DE   Flags: Precursor;
GN   Name=PCDHA11; Synonyms=CNRS7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDAC_HUMAN             Reviewed;         941 AA.
AC   Q9UN75; O75278; Q2M1N8;
DE   RecName: Full=Protocadherin alpha-12;
DE            Short=PCDH-alpha-12;
DE   Flags: Precursor;
GN   Name=PCDHA12;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDAD_HUMAN             Reviewed;         950 AA.
AC   Q9Y5I0; O75277;
DE   RecName: Full=Protocadherin alpha-13;
DE            Short=PCDH-alpha-13;
DE   Flags: Precursor;
GN   Name=PCDHA13; Synonyms=CNRS5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDB1_HUMAN             Reviewed;         818 AA.
AC   Q9Y5F3; Q2M257;
DE   RecName: Full=Protocadherin beta-1;
DE            Short=PCDH-beta-1;
DE   Flags: Precursor;
GN   Name=PCDHB1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDB2_HUMAN             Reviewed;         798 AA.
AC   Q9Y5E7; Q4KMU1;
DE   RecName: Full=Protocadherin beta-2;
DE            Short=PCDH-beta-2;
DE   Flags: Precursor;
GN   Name=PCDHB2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDB3_HUMAN             Reviewed;         796 AA.
AC   Q9Y5E6; B2R8P2;
DE   RecName: Full=Protocadherin beta-3;
DE            Short=PCDH-beta-3;
DE   Flags: Precursor;
GN   Name=PCDHB3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDB4_HUMAN             Reviewed;         795 AA.
AC   Q9Y5E5; Q4V761;
DE   RecName: Full=Protocadherin beta-4;
DE            Short=PCDH-beta-4;
DE   Flags: Precursor;
GN   Name=PCDHB4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDB6_HUMAN             Reviewed;         794 AA.
AC   Q9Y5E3; B2R8R9;
DE   RecName: Full=Protocadherin beta-6;
DE            Short=PCDH-beta-6;
DE   Flags: Precursor;
GN   Name=PCDHB6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDB5_HUMAN             Reviewed;         795 AA.
AC   Q9Y5E4; Q549F4; Q9UFU9;
DE   RecName: Full=Protocadherin beta-5;
DE            Short=PCDH-beta-5;
DE   Flags: Precursor;
GN   Name=PCDHB5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDB7_HUMAN             Reviewed;         793 AA.
AC   Q9Y5E2; A1L3Y8;
DE   RecName: Full=Protocadherin beta-7;
DE            Short=PCDH-beta-7;
DE   Flags: Precursor;
GN   Name=PCDHB7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDB9_HUMAN             Reviewed;         797 AA.
AC   Q9Y5E1; Q2M2U8; Q496X9; Q9NRJ8;
DE   RecName: Full=Protocadherin beta-9;
DE            Short=PCDH-beta-9;
DE   AltName: Full=Protocadherin-3H;
DE   Flags: Precursor;
GN   Name=PCDHB9; Synonyms=PCDH3H;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDBA_HUMAN             Reviewed;         800 AA.
AC   Q9UN67; Q96T99;
DE   RecName: Full=Protocadherin beta-10;
DE            Short=PCDH-beta-10;
DE   Flags: Precursor;
GN   Name=PCDHB10; ORFNames=UNQ1906/PRO4352;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDB8_HUMAN             Reviewed;         801 AA.
AC   Q9UN66; B9EGV1;
DE   RecName: Full=Protocadherin beta-8;
DE            Short=PCDH-beta-8;
DE   AltName: Full=Protocadherin-3I;
DE   Flags: Precursor;
GN   Name=PCDHB8; Synonyms=PCDH3I;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDBB_HUMAN             Reviewed;         797 AA.
AC   Q9Y5F2; Q2M223;
DE   RecName: Full=Protocadherin beta-11;
DE            Short=PCDH-beta-11;
DE   Flags: Precursor;
GN   Name=PCDHB11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDBC_HUMAN             Reviewed;         795 AA.
AC   Q9Y5F1; B4DDU1;
DE   RecName: Full=Protocadherin beta-12;
DE            Short=PCDH-beta-12;
DE   Flags: Precursor;
GN   Name=PCDHB12;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDBD_HUMAN             Reviewed;         798 AA.
AC   Q9Y5F0; A8K9V6;
DE   RecName: Full=Protocadherin beta-13;
DE            Short=PCDH-beta-13;
DE   Flags: Precursor;
GN   Name=PCDHB13; ORFNames=UNQ332/PRO531;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDBF_HUMAN             Reviewed;         787 AA.
AC   Q9Y5E8; Q8IUX5;
DE   RecName: Full=Protocadherin beta-15;
DE            Short=PCDH-beta-15;
DE   Flags: Precursor;
GN   Name=PCDHB15;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDBE_HUMAN             Reviewed;         798 AA.
AC   Q9Y5E9; Q4FZA4; Q4KN11;
DE   RecName: Full=Protocadherin beta-14;
DE            Short=PCDH-beta-14;
DE   Flags: Precursor;
GN   Name=PCDHB14;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDBG_HUMAN             Reviewed;         776 AA.
AC   Q9NRJ7; B3KPK5; Q8IYD5; Q96SE9; Q9HCF1;
DE   RecName: Full=Protocadherin beta-16;
DE            Short=PCDH-beta-16;
DE   AltName: Full=Protocadherin-3X;
DE   Flags: Precursor;
GN   Name=PCDHB16; Synonyms=KIAA1621, PCDH3X;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   PCDBI_HUMAN             Reviewed;         734 AA.
AC   Q96TA0; B3KTF8;
DE   RecName: Full=Putative protocadherin beta-18;
DE            Short=PCDH-beta-18;
DE   AltName: Full=PCDH-psi2;
GN   Name=PCDHB18;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDC1_HUMAN             Reviewed;         963 AA.
AC   Q9H158; Q9Y5F5; Q9Y5I5;
DE   RecName: Full=Protocadherin alpha-C1;
DE            Short=PCDH-alpha-C1;
DE   Flags: Precursor;
GN   Name=PCDHAC1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDC2_HUMAN             Reviewed;        1007 AA.
AC   Q9Y5I4; Q2M3V1; Q9Y5F4;
DE   RecName: Full=Protocadherin alpha-C2;
DE            Short=PCDH-alpha-C2;
DE   Flags: Precursor;
GN   Name=PCDHAC2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDG1_HUMAN             Reviewed;         931 AA.
AC   Q9Y5H4; Q9Y5D6;
DE   RecName: Full=Protocadherin gamma-A1;
DE            Short=PCDH-gamma-A1;
DE   Flags: Precursor;
GN   Name=PCDHGA1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG2_HUMAN             Reviewed;         932 AA.
AC   Q9Y5H1; Q52LL6; Q9Y5D5;
DE   RecName: Full=Protocadherin gamma-A2;
DE            Short=PCDH-gamma-A2;
DE   Flags: Precursor;
GN   Name=PCDHGA2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG3_HUMAN             Reviewed;         932 AA.
AC   Q9Y5H0; Q9Y5D4;
DE   RecName: Full=Protocadherin gamma-A3;
DE            Short=PCDH-gamma-A3;
DE   Flags: Precursor;
GN   Name=PCDHGA3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG4_HUMAN             Reviewed;         931 AA.
AC   Q9Y5G9; Q9Y5D3;
DE   RecName: Full=Protocadherin gamma-A4;
DE            Short=PCDH-gamma-A4;
DE   Flags: Precursor;
GN   Name=PCDHGA4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PCDG5_HUMAN             Reviewed;         931 AA.
AC   Q9Y5G8; Q2M3F5; Q9Y5D2;
DE   RecName: Full=Protocadherin gamma-A5;
DE            Short=PCDH-gamma-A5;
DE   Flags: Precursor;
GN   Name=PCDHGA5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG6_HUMAN             Reviewed;         932 AA.
AC   Q9Y5G7; A6H8K7; B2RN55; Q9Y5D1;
DE   RecName: Full=Protocadherin gamma-A6;
DE            Short=PCDH-gamma-A6;
DE   Flags: Precursor;
GN   Name=PCDHGA6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG7_HUMAN             Reviewed;         932 AA.
AC   Q9Y5G6; B2RN87; Q9Y5D0;
DE   RecName: Full=Protocadherin gamma-A7;
DE            Short=PCDH-gamma-A7;
DE   Flags: Precursor;
GN   Name=PCDHGA7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG8_HUMAN             Reviewed;         932 AA.
AC   Q9Y5G5; A7MCZ4; O15039;
DE   RecName: Full=Protocadherin gamma-A8;
DE            Short=PCDH-gamma-A8;
DE   Flags: Precursor;
GN   Name=PCDHGA8; Synonyms=KIAA0327;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDG9_HUMAN             Reviewed;         932 AA.
AC   Q9Y5G4; A2RU65; Q9Y5C9;
DE   RecName: Full=Protocadherin gamma-A9;
DE            Short=PCDH-gamma-A9;
DE   Flags: Precursor;
GN   Name=PCDHGA9;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGA_HUMAN             Reviewed;         936 AA.
AC   Q9Y5H3; Q9Y5E0;
DE   RecName: Full=Protocadherin gamma-A10;
DE            Short=PCDH-gamma-A10;
DE   Flags: Precursor;
GN   Name=PCDHGA10;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGC_HUMAN             Reviewed;         932 AA.
AC   O60330; O15100; Q6UW70; Q9Y5D7;
DE   RecName: Full=Protocadherin gamma-A12;
DE            Short=PCDH-gamma-A12;
DE   AltName: Full=Cadherin-21;
DE   AltName: Full=Fibroblast cadherin-3;
DE   Flags: Precursor;
GN   Name=PCDHGA12; Synonyms=CDH21, FIB3, KIAA0588; ORFNames=UNQ371/PRO707;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGB_HUMAN             Reviewed;         935 AA.
AC   Q9Y5H2; B7ZVY8; Q9Y5D8; Q9Y5D9;
DE   RecName: Full=Protocadherin gamma-A11;
DE            Short=PCDH-gamma-A11;
DE   Flags: Precursor;
GN   Name=PCDHGA11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGD_HUMAN             Reviewed;         927 AA.
AC   Q9Y5G3; Q3SY75; Q9Y5C8;
DE   RecName: Full=Protocadherin gamma-B1;
DE            Short=PCDH-gamma-B1;
DE   Flags: Precursor;
GN   Name=PCDHGB1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGE_HUMAN             Reviewed;         931 AA.
AC   Q9Y5G2; Q3MIJ3; Q9UN65;
DE   RecName: Full=Protocadherin gamma-B2;
DE            Short=PCDH-gamma-B2;
DE   Flags: Precursor;
GN   Name=PCDHGB2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGF_HUMAN             Reviewed;         929 AA.
AC   Q9Y5G1; A7E229; Q9Y5C7;
DE   RecName: Full=Protocadherin gamma-B3;
DE            Short=PCDH-gamma-B3;
DE   Flags: Precursor;
GN   Name=PCDHGB3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGG_HUMAN             Reviewed;         923 AA.
AC   Q9UN71; O15099; Q2M267; Q9UN64;
DE   RecName: Full=Protocadherin gamma-B4;
DE            Short=PCDH-gamma-B4;
DE   AltName: Full=Cadherin-20;
DE   AltName: Full=Fibroblast cadherin-2;
DE   Flags: Precursor;
GN   Name=PCDHGB4; Synonyms=CDH20, FIB2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGH_HUMAN             Reviewed;         923 AA.
AC   Q9Y5G0; Q52LK8; Q9Y5C6;
DE   RecName: Full=Protocadherin gamma-B5;
DE            Short=PCDH-gamma-B5;
DE   Flags: Precursor;
GN   Name=PCDHGB5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGI_HUMAN             Reviewed;         930 AA.
AC   Q9Y5F9; Q9Y5C5;
DE   RecName: Full=Protocadherin gamma-B6;
DE            Short=PCDH-gamma-B6;
DE   Flags: Precursor;
GN   Name=PCDHGB6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGJ_HUMAN             Reviewed;         929 AA.
AC   Q9Y5F8; Q9UN63;
DE   RecName: Full=Protocadherin gamma-B7;
DE            Short=PCDH-gamma-B7;
DE   Flags: Precursor;
GN   Name=PCDHGB7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGL_HUMAN             Reviewed;         938 AA.
AC   Q9Y5F7; Q495T2; Q9Y5C3;
DE   RecName: Full=Protocadherin gamma-C4;
DE            Short=PCDH-gamma-C4;
DE   Flags: Precursor;
GN   Name=PCDHGC4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDGM_HUMAN             Reviewed;         944 AA.
AC   Q9Y5F6; Q9Y5C2;
DE   RecName: Full=Protocadherin gamma-C5;
DE            Short=PCDH-gamma-C5;
DE   Flags: Precursor;
GN   Name=PCDHGC5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDH1_HUMAN             Reviewed;        1060 AA.
AC   Q08174; Q8IUP2;
DE   RecName: Full=Protocadherin-1;
DE   AltName: Full=Cadherin-like protein 1;
DE   AltName: Full=Protocadherin-42;
DE            Short=PC42;
DE   Flags: Precursor;
GN   Name=PCDH1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PCDGK_HUMAN             Reviewed;         934 AA.
AC   Q9UN70; O60622; Q08192; Q9Y5C4;
DE   RecName: Full=Protocadherin gamma-C3;
DE            Short=PCDH-gamma-C3;
DE   AltName: Full=Protocadherin-2;
DE   AltName: Full=Protocadherin-43;
DE            Short=PC-43;
DE   Flags: Precursor;
GN   Name=PCDHGC3; Synonyms=PCDH2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0016339; P:calcium-dependent cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDH7_HUMAN             Reviewed;        1069 AA.
AC   O60245; O60246; O60247; Q4W5C4;
DE   RecName: Full=Protocadherin-7;
DE   AltName: Full=Brain-heart protocadherin;
DE            Short=BH-Pcdh;
DE   Flags: Precursor;
GN   Name=PCDH7; Synonyms=BHPCDH;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDH8_HUMAN             Reviewed;        1070 AA.
AC   O95206; B4DMV7; Q5TAN1; Q5TAN2; Q8IYE9; Q96SF1;
DE   RecName: Full=Protocadherin-8;
DE   AltName: Full=Arcadlin;
DE   Flags: Precursor;
GN   Name=PCDH8;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   PCDH9_HUMAN             Reviewed;        1237 AA.
AC   Q9HC56; A2A6U1; Q5VT83; Q7Z3U0; Q8N3K7;
DE   RecName: Full=Protocadherin-9;
DE   Flags: Precursor;
GN   Name=PCDH9;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
//
ID   PCDP1_HUMAN             Reviewed;         840 AA.
AC   Q4G0U5; B4DEK0; B4E2T5;
DE   RecName: Full=Primary ciliary dyskinesia protein 1;
GN   Name=PCDP1;
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0003341; P:cilium movement; IEA:Ensembl.
//
ID   PCF11_HUMAN             Reviewed;        1555 AA.
AC   O94913; A6H8W7; O43671; Q6P0X8;
DE   RecName: Full=Pre-mRNA cleavage complex 2 protein Pcf11;
DE   AltName: Full=Pre-mRNA cleavage complex II protein Pcf11;
GN   Name=PCF11; Synonyms=KIAA0824;
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006379; P:mRNA cleavage; NAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   PCFT_HUMAN              Reviewed;         459 AA.
AC   Q96NT5; Q1HE20; Q86T92; Q8TEG3; Q96FL0;
DE   RecName: Full=Proton-coupled folate transporter;
DE   AltName: Full=G21;
DE   AltName: Full=Heme carrier protein 1;
DE   AltName: Full=PCFT/HCP1;
DE   AltName: Full=Solute carrier family 46 member 1;
GN   Name=SLC46A1; Synonyms=HCP1, PCFT;
DR   GuidetoPHARMACOLOGY; 1213; -.
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008517; F:folic acid transporter activity; IDA:UniProtKB.
DR   GO; GO:0015232; F:heme transporter activity; IEA:Ensembl.
DR   GO; GO:0015350; F:methotrexate transporter activity; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0015884; P:folic acid transport; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PCGF1_HUMAN             Reviewed;         259 AA.
AC   Q9BSM1; Q7Z506;
DE   RecName: Full=Polycomb group RING finger protein 1;
DE   AltName: Full=Nervous system Polycomb-1;
DE            Short=NSPc1;
DE   AltName: Full=RING finger protein 68;
GN   Name=PCGF1; Synonyms=NSPC1, RNF68;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PCGF3_HUMAN             Reviewed;         242 AA.
AC   Q3KNV8; D3DVN1; O15262;
DE   RecName: Full=Polycomb group RING finger protein 3;
DE   AltName: Full=RING finger protein 3A;
GN   Name=PCGF3; Synonyms=RNF3, RNF3A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PCGF5_HUMAN             Reviewed;         256 AA.
AC   Q86SE9; B7Z892; D3DR33; Q6PK47; Q86TD0;
DE   RecName: Full=Polycomb group RING finger protein 5;
DE   AltName: Full=RING finger protein 159;
GN   Name=PCGF5; Synonyms=RNF159;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PCGF2_HUMAN             Reviewed;         344 AA.
AC   P35227; A6NGD8;
DE   RecName: Full=Polycomb group RING finger protein 2;
DE   AltName: Full=DNA-binding protein Mel-18;
DE   AltName: Full=RING finger protein 110;
DE   AltName: Full=Zinc finger protein 144;
GN   Name=PCGF2; Synonyms=MEL18, RNF110, ZNF144;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0016573; P:histone acetylation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PCGF6_HUMAN             Reviewed;         350 AA.
AC   Q9BYE7; A8K3R4; Q5SYD1; Q5SYD6; Q96ID9; Q96SJ1;
DE   RecName: Full=Polycomb group RING finger protein 6;
DE   AltName: Full=Mel18 and Bmi1-like RING finger;
DE   AltName: Full=RING finger protein 134;
GN   Name=PCGF6; Synonyms=MBLR, RNF134;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PCH2_HUMAN              Reviewed;         432 AA.
AC   Q15645; C9K0T3; D3DTC0; O15324;
DE   RecName: Full=Pachytene checkpoint protein 2 homolog;
DE   AltName: Full=Human papillomavirus type 16 E1 protein-binding protein;
DE            Short=16E1-BP;
DE            Short=HPV16 E1 protein-binding protein;
DE   AltName: Full=Thyroid hormone receptor interactor 13;
DE   AltName: Full=Thyroid receptor-interacting protein 13;
DE            Short=TR-interacting protein 13;
DE            Short=TRIP-13;
GN   Name=TRIP13; Synonyms=PCH2;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0006302; P:double-strand break repair; ISS:UniProtKB.
DR   GO; GO:0007144; P:female meiosis I; IEA:Ensembl.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0048477; P:oogenesis; ISS:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PCID2_HUMAN             Reviewed;         399 AA.
AC   Q5JVF3; A6NK09; Q3ZCX1; Q5TC57; Q5TC58; Q9H7K1; Q9HBZ7; Q9NUK6;
AC   Q9NVY1; Q9NW44; Q9NWH3;
DE   RecName: Full=PCI domain-containing protein 2;
DE   AltName: Full=CSN12-like protein;
GN   Name=PCID2; ORFNames=HT004;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000117; P:negative regulation of cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0043488; P:regulation of mRNA stability; IMP:UniProtKB.
DR   GO; GO:0048536; P:spleen development; ISS:UniProtKB.
//
ID   PCIF1_HUMAN             Reviewed;         704 AA.
AC   Q9H4Z3; E1P5P1; Q54AB9; Q9NT85;
DE   RecName: Full=Phosphorylated CTD-interacting factor 1;
GN   Name=PCIF1; Synonyms=C20orf67;
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PCKGC_HUMAN             Reviewed;         622 AA.
AC   P35558; A8K437; Q8TCA3; Q9UJD2;
DE   RecName: Full=Phosphoenolpyruvate carboxykinase, cytosolic [GTP];
DE            Short=PEPCK-C;
DE            EC=4.1.1.32;
GN   Name=PCK1; Synonyms=PEPCK1;
DR   GO; GO:0031406; F:carboxylic acid binding; IDA:BHF-UCL.
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:BHF-UCL.
DR   GO; GO:0030145; F:manganese ion binding; IDA:BHF-UCL.
DR   GO; GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; ISS:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0017144; P:drug metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; ISS:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006006; P:glucose metabolic process; IMP:BHF-UCL.
DR   GO; GO:0046327; P:glycerol biosynthetic process from pyruvate; ISS:BHF-UCL.
DR   GO; GO:0006475; P:internal protein amino acid acetylation; IDA:UniProtKB.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PCKGM_HUMAN             Reviewed;         640 AA.
AC   Q16822; O43253; Q86U01; Q9BV62;
DE   RecName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial;
DE            Short=PEPCK-M;
DE            EC=4.1.1.32;
DE   Flags: Precursor;
GN   Name=PCK2; Synonyms=PEPCK2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004613; F:phosphoenolpyruvate carboxykinase (GTP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004611; F:phosphoenolpyruvate carboxykinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006116; P:NADH oxidation; IEA:Ensembl.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PCLI1_HUMAN             Reviewed;         250 AA.
AC   Q7Z2X4; B3KU82; Q68CJ2; Q6ZUS3; Q8IXL0; Q9NWP6;
DE   RecName: Full=PTB-containing, cubilin and LRP1-interacting protein;
DE            Short=P-CLI1;
DE   AltName: Full=Phosphotyrosine interaction domain-containing protein 1;
DE   AltName: Full=Protein NYGGF4;
GN   Name=PID1; Synonyms=NYGGF4, PCLI1; ORFNames=HMFN2073;
DR   GO; GO:0071345; P:cellular response to cytokine stimulus; ISS:BHF-UCL.
DR   GO; GO:0071398; P:cellular response to fatty acid; ISS:BHF-UCL.
DR   GO; GO:0071354; P:cellular response to interleukin-6; ISS:BHF-UCL.
DR   GO; GO:0044320; P:cellular response to leptin stimulus; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; ISS:BHF-UCL.
DR   GO; GO:0006112; P:energy reserve metabolic process; IC:BHF-UCL.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:BHF-UCL.
DR   GO; GO:2001170; P:negative regulation of ATP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:2001274; P:negative regulation of glucose import in response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0090298; P:negative regulation of mitochondrial DNA replication; IMP:BHF-UCL.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:2001171; P:positive regulation of ATP biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0070346; P:positive regulation of fat cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0010635; P:regulation of mitochondrial fusion; IC:BHF-UCL.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; ISS:BHF-UCL.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; ISS:BHF-UCL.
//
ID   PCLO_HUMAN              Reviewed;        5065 AA.
AC   Q9Y6V0; A4D1A7; A6NNX9; O43373; O60305; Q08E72; Q9BVC8; Q9UIV2;
AC   Q9Y6U9;
DE   RecName: Full=Protein piccolo;
DE   AltName: Full=Aczonin;
GN   Name=PCLO; Synonyms=ACZ, KIAA0559;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0005522; F:profilin binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; NAS:UniProtKB.
//
ID   PCM1_HUMAN              Reviewed;        2024 AA.
AC   Q15154; Q58F13; Q6P1K7; Q8NB85; Q9BWC1; Q9H4A2;
DE   RecName: Full=Pericentriolar material 1 protein;
DE            Short=PCM-1;
DE            Short=hPCM-1;
GN   Name=PCM1;
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IMP:BHF-UCL.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0022027; P:interkinetic nuclear migration; ISS:BHF-UCL.
DR   GO; GO:0035735; P:intraciliary transport involved in cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; ISS:BHF-UCL.
DR   GO; GO:0034454; P:microtubule anchoring at centrosome; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:BHF-UCL.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0071539; P:protein localization to centrosome; ISS:BHF-UCL.
//
ID   PCMD1_HUMAN             Reviewed;         357 AA.
AC   Q96MG8; Q96FK9;
DE   RecName: Full=Protein-L-isoaspartate O-methyltransferase domain-containing protein 1;
GN   Name=PCMTD1;
DR   GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
//
ID   PCMD2_HUMAN             Reviewed;         361 AA.
AC   Q9NV79; E1P5H3; Q8IW60; Q9H4K2;
DE   RecName: Full=Protein-L-isoaspartate O-methyltransferase domain-containing protein 2;
GN   Name=PCMTD2; Synonyms=C20orf36;
DR   GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
//
ID   PCNA_HUMAN              Reviewed;         261 AA.
AC   P12004; B2R897; D3DW02;
DE   RecName: Full=Proliferating cell nuclear antigen;
DE            Short=PCNA;
DE   AltName: Full=Cyclin;
GN   Name=PCNA;
DR   GO; GO:0032139; F:dinucleotide insertion or deletion binding; IDA:BHF-UCL.
DR   GO; GO:0070182; F:DNA polymerase binding; IPI:UniProt.
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0032405; F:MutLalpha complex binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000701; F:purine-specific mismatch base pair DNA N-glycosylase activity; IDA:BHF-UCL.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0006298; P:mismatch repair; IDA:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0032077; P:positive regulation of deoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0033993; P:response to lipid; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0019985; P:translesion synthesis; IDA:UniProtKB.
//
ID   PCNP_HUMAN              Reviewed;         178 AA.
AC   Q8WW12; B2RBE7; D3DN52; Q53GF3; Q6AI44; Q96CU3; Q9NS81;
DE   RecName: Full=PEST proteolytic signal-containing nuclear protein;
DE            Short=PCNP;
DE            Short=PEST-containing nuclear protein;
GN   Name=PCNP;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:HGNC.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:HGNC.
//
ID   PCNT_HUMAN              Reviewed;        3336 AA.
AC   O95613; O43152; Q7Z7C9;
DE   RecName: Full=Pericentrin;
DE   AltName: Full=Kendrin;
DE   AltName: Full=Pericentrin-B;
GN   Name=PCNT; Synonyms=KIAA0402, PCNT2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048854; P:brain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021696; P:cerebellar cortex morphogenesis; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IDA:MGI.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0061351; P:neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IEA:Ensembl.
//
ID   PCOC1_HUMAN             Reviewed;         449 AA.
AC   Q15113; B2R9E1; O14550;
DE   RecName: Full=Procollagen C-endopeptidase enhancer 1;
DE   AltName: Full=Procollagen COOH-terminal proteinase enhancer 1;
DE            Short=PCPE-1;
DE            Short=Procollagen C-proteinase enhancer 1;
DE   AltName: Full=Type 1 procollagen C-proteinase enhancer protein;
DE   AltName: Full=Type I procollagen COOH-terminal proteinase enhancer;
DE   Flags: Precursor;
GN   Name=PCOLCE; Synonyms=PCPE1;
DR   GO; GO:0005518; F:collagen binding; IDA:MGI.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0016504; F:peptidase activator activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0010952; P:positive regulation of peptidase activity; IDA:GOC.
DR   GO; GO:0006508; P:proteolysis; IEA:Ensembl.
//
ID   PCOC2_HUMAN             Reviewed;         415 AA.
AC   Q9UKZ9; B2RCH9; D3DNG4; Q9BRH3;
DE   RecName: Full=Procollagen C-endopeptidase enhancer 2;
DE   AltName: Full=Procollagen COOH-terminal proteinase enhancer 2;
DE            Short=PCPE-2;
DE            Short=Procollagen C-proteinase enhancer 2;
DE   Flags: Precursor;
GN   Name=PCOLCE2; Synonyms=PCPE2; ORFNames=UNQ250/PRO287;
DR   GO; GO:0005518; F:collagen binding; IDA:MGI.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0016504; F:peptidase activator activity; IDA:MGI.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0010952; P:positive regulation of peptidase activity; IDA:GOC.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:InterPro.
//
ID   PCOTH_HUMAN             Reviewed;         107 AA.
AC   Q58A44;
DE   RecName: Full=Protein PCOTH;
DE   AltName: Full=Prostate collagen triple helix protein;
GN   Name=PCOTH;
//
ID   PCP4_HUMAN              Reviewed;          62 AA.
AC   P48539; A6NDJ9; Q6ICS4; Q93059;
DE   RecName: Full=Purkinje cell protein 4;
DE   AltName: Full=Brain-specific antigen PCP-4;
DE   AltName: Full=Brain-specific polypeptide PEP-19;
GN   Name=PCP4; Synonyms=PEP19;
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
//
ID   PCP2_HUMAN              Reviewed;         136 AA.
AC   Q8IVA1; Q3KRG7;
DE   RecName: Full=Purkinje cell protein 2 homolog;
GN   Name=PCP2;
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; IEA:Ensembl.
//
ID   PCP_HUMAN               Reviewed;         496 AA.
AC   P42785; A8MU24; B2R7B7; B3KRK5; B5BU34;
DE   RecName: Full=Lysosomal Pro-X carboxypeptidase;
DE            EC=3.4.16.2;
DE   AltName: Full=Angiotensinase C;
DE   AltName: Full=Lysosomal carboxypeptidase C;
DE   AltName: Full=Proline carboxypeptidase;
DE   AltName: Full=Prolylcarboxypeptidase;
DE            Short=PRCP;
DE   Flags: Precursor;
GN   Name=PRCP; Synonyms=PCP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004185; F:serine-type carboxypeptidase activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
//
ID   PCSK1_HUMAN             Reviewed;         260 AA.
AC   Q9UHG2; Q4VC04;
DE   RecName: Full=ProSAAS;
DE   AltName: Full=Proprotein convertase subtilisin/kexin type 1 inhibitor;
DE            Short=Proprotein convertase 1 inhibitor;
DE   AltName: Full=pro-SAAS;
DE   Contains:
DE     RecName: Full=KEP;
DE   Contains:
DE     RecName: Full=Big SAAS;
DE              Short=b-SAAS;
DE   Contains:
DE     RecName: Full=Little SAAS;
DE              Short=l-SAAS;
DE     AltName: Full=N-proSAAS;
DE   Contains:
DE     RecName: Full=Big PEN-LEN;
DE              Short=b-PEN-LEN;
DE     AltName: Full=SAAS CT(1-49);
DE   Contains:
DE     RecName: Full=PEN;
DE   Contains:
DE     RecName: Full=Little LEN;
DE              Short=l-LEN;
DE   Contains:
DE     RecName: Full=Big LEN;
DE              Short=b-LEN;
DE     AltName: Full=SAAS CT(25-40);
DE   Flags: Precursor;
GN   Name=PCSK1N;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0016486; P:peptide hormone processing; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
//
ID   PCSK4_HUMAN             Reviewed;         755 AA.
AC   Q6UW60; Q8IY88; Q9UF79;
DE   RecName: Full=Proprotein convertase subtilisin/kexin type 4;
DE            EC=3.4.21.-;
DE   AltName: Full=Proprotein convertase 4;
DE            Short=PC4;
DE   Flags: Precursor;
GN   Name=PCSK4; Synonyms=PC4; ORFNames=UNQ2757/PRO6496;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0048240; P:sperm capacitation; IEA:Ensembl.
//
ID   PCSK5_HUMAN             Reviewed;        1860 AA.
AC   Q92824; F5H2G7; Q13527; Q96EP4;
DE   RecName: Full=Proprotein convertase subtilisin/kexin type 5;
DE            EC=3.4.21.-;
DE   AltName: Full=Proprotein convertase 5;
DE            Short=PC5;
DE   AltName: Full=Proprotein convertase 6;
DE            Short=PC6;
DE            Short=hPC6;
DE   AltName: Full=Subtilisin/kexin-like protease PC5;
DE   Flags: Precursor;
GN   Name=PCSK5; Synonyms=PC5, PC6;
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0042277; F:peptide binding; ISS:BHF-UCL.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IMP:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0042089; P:cytokine biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0007566; P:embryo implantation; ISS:BHF-UCL.
DR   GO; GO:0048566; P:embryonic digestive tract development; IMP:BHF-UCL.
DR   GO; GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:0035108; P:limb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0032455; P:nerve growth factor processing; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043043; P:peptide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.
DR   GO; GO:0016485; P:protein processing; IDA:BHF-UCL.
DR   GO; GO:0002001; P:renin secretion into blood stream; IEP:BHF-UCL.
DR   GO; GO:0030323; P:respiratory tube development; ISS:BHF-UCL.
DR   GO; GO:0006465; P:signal peptide processing; IDA:HGNC.
DR   GO; GO:0019058; P:viral life cycle; IEP:BHF-UCL.
//
ID   PCSK6_HUMAN             Reviewed;         969 AA.
AC   P29122; Q15099; Q15100; Q9UEG7; Q9UEJ1; Q9UEJ2; Q9UEJ7; Q9UEJ8;
AC   Q9UEJ9; Q9Y4G9; Q9Y4H0; Q9Y4H1;
DE   RecName: Full=Proprotein convertase subtilisin/kexin type 6;
DE            EC=3.4.21.-;
DE   AltName: Full=Paired basic amino acid cleaving enzyme 4;
DE   AltName: Full=Subtilisin-like proprotein convertase 4;
DE            Short=SPC4;
DE   AltName: Full=Subtilisin/kexin-like protease PACE4;
DE   Flags: Precursor;
GN   Name=PCSK6; Synonyms=PACE4;
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0032455; P:nerve growth factor processing; TAS:Reactome.
DR   GO; GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016486; P:peptide hormone processing; IDA:BHF-UCL.
DR   GO; GO:0016485; P:protein processing; IDA:BHF-UCL.
DR   GO; GO:0030510; P:regulation of BMP signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0032940; P:secretion by cell; IDA:BHF-UCL.
DR   GO; GO:0007354; P:zygotic determination of anterior/posterior axis, embryo; IEA:Ensembl.
//
ID   PCSK7_HUMAN             Reviewed;         785 AA.
AC   Q16549; B0YJ60; Q3C1X1; Q53GM4; Q96FK8; Q9UL57;
DE   RecName: Full=Proprotein convertase subtilisin/kexin type 7;
DE            EC=3.4.21.-;
DE   AltName: Full=Lymphoma proprotein convertase;
DE   AltName: Full=Prohormone convertase 7;
DE   AltName: Full=Proprotein convertase 7;
DE            Short=PC7;
DE   AltName: Full=Proprotein convertase 8;
DE            Short=PC8;
DE            Short=hPC8;
DE   AltName: Full=Subtilisin/kexin-like protease PC7;
DE   Flags: Precursor;
GN   Name=PCSK7; Synonyms=LPC, PC7, PC8, SPC7;
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0016486; P:peptide hormone processing; NAS:UniProtKB.
DR   GO; GO:0016485; P:protein processing; IDA:MGI.
//
ID   PCSK9_HUMAN             Reviewed;         692 AA.
AC   Q8NBP7; A8T640; C0JYY9; Q5PSM5; Q5SZQ2;
DE   RecName: Full=Proprotein convertase subtilisin/kexin type 9;
DE            EC=3.4.21.-;
DE   AltName: Full=Neural apoptosis-regulated convertase 1;
DE            Short=NARC-1;
DE   AltName: Full=Proprotein convertase 9;
DE            Short=PC9;
DE   AltName: Full=Subtilisin/kexin-like protease PC9;
DE   Flags: Precursor;
GN   Name=PCSK9; Synonyms=NARC1; ORFNames=PSEC0052;
DR   GO; GO:0034185; F:apolipoprotein binding; ISS:UniProtKB.
DR   GO; GO:0034190; F:apolipoprotein receptor binding; IDA:BHF-UCL.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; ISS:UniProtKB.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:HGNC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:HGNC.
DR   GO; GO:0019871; F:sodium channel inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0034189; F:very-low-density lipoprotein particle binding; ISS:UniProtKB.
DR   GO; GO:0070326; F:very-low-density lipoprotein particle receptor binding; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:HGNC.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:HGNC.
DR   GO; GO:0042632; P:cholesterol homeostasis; IMP:HGNC.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0001822; P:kidney development; ISS:HGNC.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; ISS:HGNC.
DR   GO; GO:0032802; P:low-density lipoprotein particle receptor catabolic process; IDA:UniProtKB.
DR   GO; GO:0007041; P:lysosomal transport; IDA:BHF-UCL.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.
DR   GO; GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0001920; P:negative regulation of receptor recycling; IDA:BHF-UCL.
DR   GO; GO:0022008; P:neurogenesis; ISS:HGNC.
DR   GO; GO:0030182; P:neuron differentiation; ISS:HGNC.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IMP:HGNC.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0016540; P:protein autoprocessing; IDA:HGNC.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0032803; P:regulation of low-density lipoprotein particle receptor catabolic process; IEA:Ensembl.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0010469; P:regulation of receptor activity; IDA:BHF-UCL.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   PCTL_HUMAN              Reviewed;         291 AA.
AC   Q9Y365; O60532;
DE   RecName: Full=PCTP-like protein;
DE            Short=PCTP-L;
DE   AltName: Full=Antigen NY-CO-28;
DE   AltName: Full=START domain-containing protein 10;
DE            Short=StARD10;
DE   AltName: Full=Serologically defined colon cancer antigen 28;
DE   AltName: Full=StAR-related lipid transfer protein 10;
GN   Name=STARD10; Synonyms=SDCCAG28; ORFNames=CGI-52;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   PCX1_HUMAN              Reviewed;        2341 AA.
AC   Q96RV3; B2RTR6; O94897; Q96AI7; Q9Y2J9;
DE   RecName: Full=Pecanex-like protein 1;
DE   AltName: Full=Pecanex homolog;
GN   Name=PCNX; Synonyms=KIAA0805, KIAA0995, PCNXL1;
//
ID   PCX2_HUMAN              Reviewed;        2137 AA.
AC   A6NKB5; O43162; Q5T9Z8; Q5TDF1; Q8TEP4; Q96HP9; Q9HAL8;
DE   RecName: Full=Pecanex-like protein 2;
GN   Name=PCNXL2; Synonyms=KIAA0435;
//
ID   PCX3_HUMAN              Reviewed;        2034 AA.
AC   Q9H6A9; Q6MZN8;
DE   RecName: Full=Pecanex-like protein 3;
GN   Name=PCNXL3;
//
ID   PCX4_HUMAN              Reviewed;        1172 AA.
AC   Q63HM2; A8MXM2; Q9BQG8; Q9H9F2;
DE   RecName: Full=Pecanex-like protein 4;
DE   AltName: Full=Hepatitis C virus F protein-binding protein 2;
DE            Short=HCV F protein-binding protein 2;
GN   Name=PCNXL4; Synonyms=C14orf135, FBP2;
//
ID   PCY1A_HUMAN             Reviewed;         367 AA.
AC   P49585; A9LYK9; D3DXB1; Q86Y88;
DE   RecName: Full=Choline-phosphate cytidylyltransferase A;
DE            EC=2.7.7.15;
DE   AltName: Full=CCT-alpha;
DE   AltName: Full=CTP:phosphocholine cytidylyltransferase A;
DE            Short=CCT A;
DE            Short=CT A;
DE   AltName: Full=Phosphorylcholine transferase A;
GN   Name=PCYT1A; Synonyms=CTPCT, PCYT1;
DR   GO; GO:0004105; F:choline-phosphate cytidylyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:Ensembl.
DR   GO; GO:0006657; P:CDP-choline pathway; ISS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PCY1B_HUMAN             Reviewed;         369 AA.
AC   Q9Y5K3; A8IX00; B2RCX8; B4DK10; E9PD84; O60621; Q86XC9;
DE   RecName: Full=Choline-phosphate cytidylyltransferase B;
DE            EC=2.7.7.15;
DE   AltName: Full=CCT-beta;
DE   AltName: Full=CTP:phosphocholine cytidylyltransferase B;
DE            Short=CCT B;
DE            Short=CT B;
DE   AltName: Full=Phosphorylcholine transferase B;
GN   Name=PCYT1B; Synonyms=CCTB;
DR   GO; GO:0004105; F:choline-phosphate cytidylyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006657; P:CDP-choline pathway; TAS:GOC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PCY2_HUMAN              Reviewed;         389 AA.
AC   Q99447; B7Z7A5; B7ZAS0; F5H8B1; Q6IBM3; Q96G08;
DE   RecName: Full=Ethanolamine-phosphate cytidylyltransferase;
DE            EC=2.7.7.14;
DE   AltName: Full=CTP:phosphoethanolamine cytidylyltransferase;
DE   AltName: Full=Phosphorylethanolamine transferase;
GN   Name=PCYT2;
DR   GO; GO:0004306; F:ethanolamine-phosphate cytidylyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PCYOX_HUMAN             Reviewed;         505 AA.
AC   Q9UHG3; B2RB14; O94982; Q8N4N5; Q96QM8;
DE   RecName: Full=Prenylcysteine oxidase 1;
DE            EC=1.8.3.5;
DE   AltName: Full=Prenylcysteine lyase;
DE   Flags: Precursor;
GN   Name=PCYOX1; Synonyms=KIAA0908, PCL1; ORFNames=UNQ597/PRO1183;
DR   GO; GO:0008555; F:chloride-transporting ATPase activity; IEA:Ensembl.
DR   GO; GO:0001735; F:prenylcysteine oxidase activity; IDA:BHF-UCL.
DR   GO; GO:0030327; P:prenylated protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0030328; P:prenylcysteine catabolic process; IEA:Ensembl.
DR   GO; GO:0030329; P:prenylcysteine metabolic process; NAS:UniProtKB.
//
ID   PCYXL_HUMAN             Reviewed;         494 AA.
AC   Q8NBM8; Q7Z4S2; Q8NCY5; Q8NF69; Q9BTE8; Q9BWS3;
DE   RecName: Full=Prenylcysteine oxidase-like;
DE            EC=1.8.3.-;
DE   Flags: Precursor;
GN   Name=PCYOX1L; ORFNames=PSEC0105;
DR   GO; GO:0001735; F:prenylcysteine oxidase activity; IEA:InterPro.
DR   GO; GO:0030328; P:prenylcysteine catabolic process; IEA:InterPro.
//
ID   PD1L1_HUMAN             Reviewed;         290 AA.
AC   Q9NZQ7; B2RBA2; B4DU27; Q14CJ2; Q2V8D5; Q66RK1; Q6WEX4; Q9NUZ5;
DE   RecName: Full=Programmed cell death 1 ligand 1;
DE            Short=PD-L1;
DE            Short=PDCD1 ligand 1;
DE            Short=Programmed death ligand 1;
DE   AltName: Full=B7 homolog 1;
DE            Short=B7-H1;
DE   AltName: CD_antigen=CD274;
DE   Flags: Precursor;
GN   Name=CD274; Synonyms=B7H1, PDCD1L1, PDCD1LG1, PDL1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:2001181; P:positive regulation of interleukin-10 secretion; IDA:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
//
ID   PD1L2_HUMAN             Reviewed;         273 AA.
AC   Q9BQ51; Q14CN8; Q5T7Z6; Q6JXL8; Q6JXL9;
DE   RecName: Full=Programmed cell death 1 ligand 2;
DE            Short=PD-1 ligand 2;
DE            Short=PD-L2;
DE            Short=PDCD1 ligand 2;
DE            Short=Programmed death ligand 2;
DE   AltName: Full=Butyrophilin B7-DC;
DE            Short=B7-DC;
DE   AltName: CD_antigen=CD273;
DE   Flags: Precursor;
GN   Name=PDCD1LG2; Synonyms=B7DC, CD273, PDCD1L2, PDL2;
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   PD2R2_HUMAN             Reviewed;         395 AA.
AC   Q9Y5Y4; O94765; Q4QRI6;
DE   RecName: Full=Prostaglandin D2 receptor 2;
DE   AltName: Full=Chemoattractant receptor-homologous molecule expressed on Th2 cells;
DE   AltName: Full=G-protein coupled receptor 44;
DE   AltName: CD_antigen=CD294;
GN   Name=PTGDR2; Synonyms=CRTH2, DL1R, GPR44;
DR   GuidetoPHARMACOLOGY; 339; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
DR   GO; GO:0004956; F:prostaglandin D receptor activity; IDA:UniProtKB.
DR   GO; GO:0004958; F:prostaglandin F receptor activity; IEA:Ensembl.
DR   GO; GO:0001785; F:prostaglandin J receptor activity; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
//
ID   PD2R_HUMAN              Reviewed;         359 AA.
AC   Q13258; Q13250; Q13251; Q1ZZ52;
DE   RecName: Full=Prostaglandin D2 receptor;
DE            Short=PGD receptor;
DE            Short=PGD2 receptor;
DE   AltName: Full=Prostanoid DP receptor;
GN   Name=PTGDR;
DR   GuidetoPHARMACOLOGY; 338; -.
DR   GO; GO:0004956; F:prostaglandin D receptor activity; NAS:UniProtKB.
DR   GO; GO:0001785; F:prostaglandin J receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0046085; P:adenosine metabolic process; IEA:Ensembl.
DR   GO; GO:0071799; P:cellular response to prostaglandin D stimulus; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
//
ID   PDC10_HUMAN             Reviewed;         212 AA.
AC   Q9BUL8; A8K515; D3DNN5; O14811;
DE   RecName: Full=Programmed cell death protein 10;
DE   AltName: Full=Cerebral cavernous malformations 3 protein;
DE   AltName: Full=TF-1 cell apoptosis-related protein 15;
GN   Name=PDCD10; Synonyms=CCM3, TFAR15;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
//
ID   PDC6I_HUMAN             Reviewed;         868 AA.
AC   Q8WUM4; E9PFU1; Q6NUS1; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5;
DE   RecName: Full=Programmed cell death 6-interacting protein;
DE            Short=PDCD6-interacting protein;
DE   AltName: Full=ALG-2-interacting protein 1;
DE   AltName: Full=ALG-2-interacting protein X;
DE   AltName: Full=Hp95;
GN   Name=PDCD6IP; Synonyms=AIP1, ALIX, KIAA1375;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PDCD1_HUMAN             Reviewed;         288 AA.
AC   Q15116; O00517; Q8IX89;
DE   RecName: Full=Programmed cell death protein 1;
DE            Short=Protein PD-1;
DE            Short=hPD-1;
DE   AltName: CD_antigen=CD279;
DE   Flags: Precursor;
GN   Name=PDCD1; Synonyms=PD1;
DR   GuidetoPHARMACOLOGY; 2760; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   PDCD2_HUMAN             Reviewed;         344 AA.
AC   Q16342; Q58HM9; Q58HN0; Q9UH12;
DE   RecName: Full=Programmed cell death protein 2;
DE   AltName: Full=Zinc finger MYND domain-containing protein 7;
DE   AltName: Full=Zinc finger protein Rp-8;
GN   Name=PDCD2; Synonyms=RP8, ZMYND7;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
//
ID   PDCD4_HUMAN             Reviewed;         469 AA.
AC   Q53EL6; B2RCV4; B5ME91; O15501; Q5VZS6; Q6PJI5; Q8TAR5; Q99834;
DE   RecName: Full=Programmed cell death protein 4;
DE   AltName: Full=Neoplastic transformation inhibitor protein;
DE   AltName: Full=Nuclear antigen H731-like;
DE   AltName: Full=Protein 197/15a;
GN   Name=PDCD4; Synonyms=H731;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007569; P:cell aging; IDA:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; NAS:UniProtKB.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   PDCD5_HUMAN             Reviewed;         125 AA.
AC   O14737; Q53YC9; Q6IB70;
DE   RecName: Full=Programmed cell death protein 5;
DE   AltName: Full=TF-1 cell apoptosis-related protein 19;
DE            Short=Protein TFAR19;
GN   Name=PDCD5; Synonyms=TFAR19;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:FlyBase.
//
ID   PDCD6_HUMAN             Reviewed;         191 AA.
AC   O75340; B2RD16; E7ESR3; Q2YDC2; Q5TZS0;
DE   RecName: Full=Programmed cell death protein 6;
DE   AltName: Full=Apoptosis-linked gene 2 protein;
DE   AltName: Full=Probable calcium-binding protein ALG-2;
GN   Name=PDCD6; Synonyms=ALG2;
DR   GO; GO:0060090; F:binding, bridging; IMP:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IDA:UniProtKB.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0051592; P:response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0036324; P:vascular endothelial growth factor receptor-2 signaling pathway; IDA:UniProtKB.
//
ID   PDCD7_HUMAN             Reviewed;         485 AA.
AC   Q8N8D1; Q96AK8; Q9Y6D7;
DE   RecName: Full=Programmed cell death protein 7;
DE   AltName: Full=ES18;
DE            Short=hES18;
GN   Name=PDCD7;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0070234; P:positive regulation of T cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; ISS:HGNC.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   PDCL2_HUMAN             Reviewed;         241 AA.
AC   Q8N4E4; A8MWA2; B9ZVQ9;
DE   RecName: Full=Phosducin-like protein 2;
GN   Name=PDCL2;
//
ID   PDCL3_HUMAN             Reviewed;         239 AA.
AC   Q9H2J4; B2RA00; Q53S68;
DE   RecName: Full=Phosducin-like protein 3;
DE   AltName: Full=HTPHLP;
DE   AltName: Full=PhPL3;
DE   AltName: Full=Viral IAP-associated factor 1;
DE            Short=VIAF-1;
GN   Name=PDCL3; Synonyms=PhLP2A, VIAF1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044183; F:protein binding involved in protein folding; IPI:MGI.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:2000059; P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:MGI.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:MGI.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:MGI.
DR   GO; GO:0006457; P:protein folding; IPI:GOC.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PDD2L_HUMAN             Reviewed;         358 AA.
AC   Q9BRP1;
DE   RecName: Full=Programmed cell death protein 2-like;
GN   Name=PDCD2L;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   PDDC1_HUMAN             Reviewed;         220 AA.
AC   Q8NB37; B7ZKW5; Q2NL76; Q6ZQY0; Q8NAE0;
DE   RecName: Full=Parkinson disease 7 domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=PDDC1;
//
ID   PDE10_HUMAN             Reviewed;         779 AA.
AC   Q9Y233; Q6FHX1; Q9HCP9; Q9NTV4; Q9ULW9; Q9Y5T1;
DE   RecName: Full=cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A;
DE            EC=3.1.4.17;
DE            EC=3.1.4.35;
GN   Name=PDE10A;
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0030552; F:cAMP binding; IDA:UniProtKB.
DR   GO; GO:0030553; F:cGMP binding; NAS:UniProtKB.
DR   GO; GO:0004118; F:cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046069; P:cGMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0043949; P:regulation of cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0010738; P:regulation of protein kinase A signaling; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PDE12_HUMAN             Reviewed;         609 AA.
AC   Q6L8Q7; B4DTU8; Q8IYU3; Q8NDU2; Q8TE78;
DE   RecName: Full=2',5'-phosphodiesterase 12;
DE            Short=2'-PDE;
DE            Short=2-PDE;
DE            EC=3.1.4.-;
DE   AltName: Full=Mitochondrial deadenylase;
DE            EC=3.1.13.4;
DE   Flags: Precursor;
GN   Name=PDE12;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   PDE11_HUMAN             Reviewed;         933 AA.
AC   Q9HCR9; Q14CD1; Q53T16; Q96S76; Q9GZY7; Q9HB46; Q9NY45;
DE   RecName: Full=Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A;
DE            EC=3.1.4.17;
DE            EC=3.1.4.35;
DE   AltName: Full=cAMP and cGMP phosphodiesterase 11A;
GN   Name=PDE11A;
DR   GuidetoPHARMACOLOGY; 1311; -.
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0030552; F:cAMP binding; IEA:Ensembl.
DR   GO; GO:0030553; F:cGMP binding; IDA:UniProtKB.
DR   GO; GO:0004118; F:cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0004112; F:cyclic-nucleotide phosphodiesterase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:Ensembl.
DR   GO; GO:0046069; P:cGMP catabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PDE1A_HUMAN             Reviewed;         535 AA.
AC   P54750; D3DPG5; Q86VZ0; Q9C0K8; Q9C0K9; Q9C0L0; Q9C0L1; Q9C0L2;
AC   Q9C0L3; Q9C0L4; Q9UFX3;
DE   RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A;
DE            Short=Cam-PDE 1A;
DE            EC=3.1.4.17;
DE   AltName: Full=61 kDa Cam-PDE;
DE   AltName: Full=hCam-1;
GN   Name=PDE1A;
DR   GuidetoPHARMACOLOGY; 1294; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0048101; F:calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0004117; F:calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0030553; F:cGMP binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:Ensembl.
DR   GO; GO:0046069; P:cGMP catabolic process; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034391; P:regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0048660; P:regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
//
ID   PDE1C_HUMAN             Reviewed;         709 AA.
AC   Q14123; B3KPC6; E9PE92; Q14124; Q8NB10;
DE   RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C;
DE            Short=Cam-PDE 1C;
DE            EC=3.1.4.17;
DE   AltName: Full=hCam-3;
GN   Name=PDE1C;
DR   GuidetoPHARMACOLOGY; 1296; -.
DR   GO; GO:0004117; F:calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
//
ID   PDE1B_HUMAN             Reviewed;         536 AA.
AC   Q01064; Q92825; Q96KP3;
DE   RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B;
DE            Short=Cam-PDE 1B;
DE            EC=3.1.4.17;
DE   AltName: Full=63 kDa Cam-PDE;
GN   Name=PDE1B; Synonyms=PDE1B1, PDES1B;
DR   GuidetoPHARMACOLOGY; 1295; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0048101; F:calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0004117; F:calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0097011; P:cellular response to granulocyte macrophage colony-stimulating factor stimulus; IDA:UniProtKB.
DR   GO; GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IDA:UniProtKB.
DR   GO; GO:0046069; P:cGMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0030224; P:monocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0001505; P:regulation of neurotransmitter levels; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042428; P:serotonin metabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:Reactome.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   PDE2A_HUMAN             Reviewed;         941 AA.
AC   O00408; E9PGI1; F6W5Z0; Q5J793;
DE   RecName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase;
DE            EC=3.1.4.17;
DE   AltName: Full=Cyclic GMP-stimulated phosphodiesterase;
DE            Short=CGS-PDE;
DE            Short=cGSPDE;
GN   Name=PDE2A;
DR   GuidetoPHARMACOLOGY; 1297; -.
DR   GO; GO:0005262; F:calcium channel activity; TAS:UniProtKB.
DR   GO; GO:0030552; F:cAMP binding; IMP:UniProtKB.
DR   GO; GO:0030553; F:cGMP binding; IDA:UniProtKB.
DR   GO; GO:0004118; F:cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0004112; F:cyclic-nucleotide phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0030911; F:TPR domain binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0071321; P:cellular response to cGMP; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IEP:UniProtKB.
DR   GO; GO:0097011; P:cellular response to granulocyte macrophage colony-stimulating factor stimulus; IDA:UniProtKB.
DR   GO; GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0046069; P:cGMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0019934; P:cGMP-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0061028; P:establishment of endothelial barrier; ISS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0030818; P:negative regulation of cAMP biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0033159; P:negative regulation of protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IMP:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IMP:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; ISS:UniProtKB.
//
ID   PDE3A_HUMAN             Reviewed;        1141 AA.
AC   Q14432; O60865; Q13348; Q17RD1;
DE   RecName: Full=cGMP-inhibited 3',5'-cyclic phosphodiesterase A;
DE            EC=3.1.4.17;
DE   AltName: Full=Cyclic GMP-inhibited phosphodiesterase A;
DE            Short=CGI-PDE A;
GN   Name=PDE3A;
DR   GuidetoPHARMACOLOGY; 1298; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0030552; F:cAMP binding; IEA:Ensembl.
DR   GO; GO:0004119; F:cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006198; P:cAMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0071321; P:cellular response to cGMP; IDA:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0019934; P:cGMP-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0016101; P:diterpenoid metabolic process; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IMP:UniProtKB.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0060282; P:positive regulation of oocyte development; IEA:Ensembl.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IMP:UniProtKB.
DR   GO; GO:0040020; P:regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   PDE3B_HUMAN             Reviewed;        1112 AA.
AC   Q13370; B7ZM37; O00639; Q14408; Q6SEI4;
DE   RecName: Full=cGMP-inhibited 3',5'-cyclic phosphodiesterase B;
DE            EC=3.1.4.17;
DE   AltName: Full=CGIPDE1;
DE            Short=CGIP1;
DE   AltName: Full=Cyclic GMP-inhibited phosphodiesterase B;
DE            Short=CGI-PDE B;
GN   Name=PDE3B;
DR   GuidetoPHARMACOLOGY; 1299; -.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; TAS:BHF-UCL.
DR   GO; GO:0004119; F:cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043422; F:protein kinase B binding; ISS:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006198; P:cAMP catabolic process; IEP:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043951; P:negative regulation of cAMP-mediated signaling; IC:BHF-UCL.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IC:BHF-UCL.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IMP:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
//
ID   PDE4A_HUMAN             Reviewed;         886 AA.
AC   P27815; O75522; O76092; Q16255; Q16691; Q5DM53; Q6PMT2; Q8IVA7;
AC   Q8WUQ3; Q9H3H2;
DE   RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4A;
DE            EC=3.1.4.53;
DE   AltName: Full=DPDE2;
DE   AltName: Full=PDE46;
GN   Name=PDE4A; Synonyms=DPDE2;
DR   GuidetoPHARMACOLOGY; 1300; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:BHF-UCL.
DR   GO; GO:0030552; F:cAMP binding; IGI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006198; P:cAMP catabolic process; IMP:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0043949; P:regulation of cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0010738; P:regulation of protein kinase A signaling; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PDE4B_HUMAN             Reviewed;         736 AA.
AC   Q07343; A5YW33; O15443; Q13945; Q5TEK4; Q5TEK5; Q5TEK6;
DE   RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4B;
DE            EC=3.1.4.53;
DE   AltName: Full=DPDE4;
DE   AltName: Full=PDE32;
GN   Name=PDE4B; Synonyms=DPDE4;
DR   GuidetoPHARMACOLOGY; 1301; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:BHF-UCL.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; ISS:BHF-UCL.
DR   GO; GO:0030552; F:cAMP binding; IGI:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006198; P:cAMP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0035690; P:cellular response to drug; ISS:BHF-UCL.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; ISS:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; ISS:BHF-UCL.
DR   GO; GO:1901898; P:negative regulation of relaxation of cardiac muscle; ISS:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0001780; P:neutrophil homeostasis; ISS:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IMP:BHF-UCL.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IMP:BHF-UCL.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; ISS:BHF-UCL.
DR   GO; GO:1901841; P:regulation of high voltage-gated calcium channel activity; ISS:BHF-UCL.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IMP:BHF-UCL.
//
ID   PDE4C_HUMAN             Reviewed;         712 AA.
AC   Q08493; B3KTC4; Q9UN44; Q9UN45; Q9UN46; Q9UPJ6;
DE   RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C;
DE            EC=3.1.4.53;
DE   AltName: Full=DPDE1;
DE   AltName: Full=PDE21;
GN   Name=PDE4C; Synonyms=DPDE1;
DR   GuidetoPHARMACOLOGY; 1302; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PDE4D_HUMAN             Reviewed;         809 AA.
AC   Q08499; O43433; Q13549; Q13550; Q13551; Q7Z2L8; Q8IV84; Q8IVA9;
AC   Q8IVD2; Q8IVD3; Q96HL4; Q9HCX7;
DE   RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D;
DE            EC=3.1.4.53;
DE   AltName: Full=DPDE3;
DE   AltName: Full=PDE43;
GN   Name=PDE4D; Synonyms=DPDE3;
DR   GuidetoPHARMACOLOGY; 1303; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IDA:BHF-UCL.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; NAS:UniProtKB.
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0031698; F:beta-2 adrenergic receptor binding; ISS:BHF-UCL.
DR   GO; GO:0030552; F:cAMP binding; IDA:BHF-UCL.
DR   GO; GO:0008144; F:drug binding; IPI:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0071875; P:adrenergic receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0086024; P:adrenergic receptor signaling pathway involved in positive regulation of heart rate; IC:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006198; P:cAMP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0019933; P:cAMP-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:BHF-UCL.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; IDA:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0061028; P:establishment of endothelial barrier; ISS:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045822; P:negative regulation of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:1901898; P:negative regulation of relaxation of cardiac muscle; ISS:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IMP:BHF-UCL.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IMP:BHF-UCL.
DR   GO; GO:0032754; P:positive regulation of interleukin-5 production; IMP:BHF-UCL.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; ISS:BHF-UCL.
DR   GO; GO:1901844; P:regulation of cell communication by electrical coupling involved in cardiac conduction; IC:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0010469; P:regulation of receptor activity; ISS:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL.
DR   GO; GO:0006939; P:smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IMP:BHF-UCL.
//
ID   PDE5A_HUMAN             Reviewed;         875 AA.
AC   O76074; A0AV69; A8K2C4; O75026; O75887; Q86UI0; Q86V66; Q9Y6Z6;
DE   RecName: Full=cGMP-specific 3',5'-cyclic phosphodiesterase;
DE            EC=3.1.4.35;
DE   AltName: Full=cGMP-binding cGMP-specific phosphodiesterase;
DE            Short=CGB-PDE;
GN   Name=PDE5A; Synonyms=PDE5;
DR   GuidetoPHARMACOLOGY; 1304; -.
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; NAS:UniProtKB.
DR   GO; GO:0030553; F:cGMP binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0046069; P:cGMP catabolic process; IDA:UniProtKB.
DR   GO; GO:0055118; P:negative regulation of cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0060282; P:positive regulation of oocyte development; IEA:Ensembl.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PDE6A_HUMAN             Reviewed;         860 AA.
AC   P16499; Q0P638;
DE   RecName: Full=Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha;
DE            Short=GMP-PDE alpha;
DE            EC=3.1.4.35;
DE   AltName: Full=PDE V-B1;
DE   Flags: Precursor;
GN   Name=PDE6A; Synonyms=PDEA;
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IMP:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0046037; P:GMP metabolic process; IMP:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PDE6B_HUMAN             Reviewed;         854 AA.
AC   P35913; B7Z9T9; E7ETT3; Q53XN5; Q9BWH5; Q9UD49;
DE   RecName: Full=Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta;
DE            Short=GMP-PDE beta;
DE            EC=3.1.4.35;
DE   Flags: Precursor;
GN   Name=PDE6B; Synonyms=PDEB;
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IMP:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0046037; P:GMP metabolic process; IMP:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PDE6C_HUMAN             Reviewed;         858 AA.
AC   P51160; A6NCR6; Q5VY29;
DE   RecName: Full=Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha';
DE            EC=3.1.4.35;
DE   AltName: Full=cGMP phosphodiesterase 6C;
DE   Flags: Precursor;
GN   Name=PDE6C; Synonyms=PDEA2;
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007603; P:phototransduction, visible light; IEA:Ensembl.
DR   GO; GO:0046549; P:retinal cone cell development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PDE6D_HUMAN             Reviewed;         150 AA.
AC   O43924; O43250;
DE   RecName: Full=Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta;
DE            Short=GMP-PDE delta;
DE   AltName: Full=Protein p17;
GN   Name=PDE6D; Synonyms=PDED;
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0005095; F:GTPase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:GOC.
DR   GO; GO:0033124; P:regulation of GTP catabolic process; ISS:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PDE7A_HUMAN             Reviewed;         482 AA.
AC   Q13946; A0AVH6; A8K436; A8K9G5; O15380; Q96T72;
DE   RecName: Full=High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A;
DE            EC=3.1.4.53;
DE   AltName: Full=HCP1;
DE   AltName: Full=TM22;
GN   Name=PDE7A;
DR   GuidetoPHARMACOLOGY; 1305; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PDE7B_HUMAN             Reviewed;         450 AA.
AC   Q9NP56; Q5W154;
DE   RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 7B;
DE            EC=3.1.4.53;
GN   Name=PDE7B;
DR   GuidetoPHARMACOLOGY; 1306; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   PDE8A_HUMAN             Reviewed;         829 AA.
AC   O60658; B3KXE6; H0YMZ7; Q6P9H3; Q969I1; Q96PC9; Q96PD0; Q96PD1;
AC   Q96T71; Q9UMB7; Q9UMC3;
DE   RecName: Full=High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A;
DE            EC=3.1.4.53;
GN   Name=PDE8A;
DR   GuidetoPHARMACOLOGY; 1307; -.
DR   GO; GO:0004115; F:3',5'-cyclic-AMP phosphodiesterase activity; IEA:Ensembl.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009187; P:cyclic nucleotide metabolic process; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   PDE8B_HUMAN             Reviewed;         885 AA.
AC   O95263; Q5J7V7; Q86XK8; Q8IUJ7; Q8IUJ8; Q8IUJ9; Q8IUK0; Q8N3T2;
DE   RecName: Full=High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B;
DE            Short=HsPDE8B;
DE            EC=3.1.4.53;
DE   AltName: Full=Cell proliferation-inducing gene 22 protein;
GN   Name=PDE8B; ORFNames=PIG22;
DR   GuidetoPHARMACOLOGY; 1308; -.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   GO; GO:0006198; P:cAMP catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009187; P:cyclic nucleotide metabolic process; NAS:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
//
ID   PDE9A_HUMAN             Reviewed;         593 AA.
AC   O76083; B2RBI5; B4DFI5; D3DSJ8; D3DSJ9; O75490; O75491; O95225;
AC   Q53Y40; Q5QD39; Q86SF7; Q86SI6; Q86SJ3; Q86WN3; Q86WN4; Q86WN5;
AC   Q86WN6; Q86WN7; Q86WN8; Q86WN9; Q86WP0;
DE   RecName: Full=High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A;
DE            EC=3.1.4.35;
GN   Name=PDE9A;
DR   GuidetoPHARMACOLOGY; 1309; -.
DR   GO; GO:0047555; F:3',5'-cyclic-GMP phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019934; P:cGMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PDGFA_HUMAN             Reviewed;         211 AA.
AC   P04085; B5BU73;
DE   RecName: Full=Platelet-derived growth factor subunit A;
DE            Short=PDGF subunit A;
DE   AltName: Full=PDGF-1;
DE   AltName: Full=Platelet-derived growth factor A chain;
DE   AltName: Full=Platelet-derived growth factor alpha polypeptide;
DE   Flags: Precursor;
GN   Name=PDGFA; Synonyms=PDGF1;
DR   GO; GO:0005518; F:collagen binding; IDA:MGI.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001775; P:cell activation; TAS:BHF-UCL.
DR   GO; GO:0030031; P:cell projection assembly; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; TAS:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001942; P:hair follicle development; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; ISS:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:0035793; P:positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; TAS:BHF-UCL.
DR   GO; GO:0060683; P:regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling; ISS:UniProtKB.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0014910; P:regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010035; P:response to inorganic substance; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IDA:BHF-UCL.
DR   GO; GO:0043588; P:skin development; ISS:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; TAS:BHF-UCL.
//
ID   PDGFC_HUMAN             Reviewed;         345 AA.
AC   Q9NRA1; B4DU34; B9EGR8; Q4W5M9; Q9UL22;
DE   RecName: Full=Platelet-derived growth factor C;
DE            Short=PDGF-C;
DE   AltName: Full=Fallotein;
DE   AltName: Full=Spinal cord-derived growth factor;
DE            Short=SCDGF;
DE   AltName: Full=VEGF-E;
DE   Contains:
DE     RecName: Full=Platelet-derived growth factor C, latent form;
DE              Short=PDGFC latent form;
DE   Contains:
DE     RecName: Full=Platelet-derived growth factor C, receptor-binding form;
DE              Short=PDGFC receptor-binding form;
DE   Flags: Precursor;
GN   Name=PDGFC; Synonyms=SCDGF; ORFNames=UNQ174/PRO200;
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
//
ID   PDGFD_HUMAN             Reviewed;         370 AA.
AC   Q9GZP0; A8K9T6; Q9BWV5;
DE   RecName: Full=Platelet-derived growth factor D;
DE            Short=PDGF-D;
DE   AltName: Full=Iris-expressed growth factor;
DE   AltName: Full=Spinal cord-derived growth factor B;
DE            Short=SCDGF-B;
DE   Contains:
DE     RecName: Full=Platelet-derived growth factor D, latent form;
DE              Short=PDGFD latent form;
DE   Contains:
DE     RecName: Full=Platelet-derived growth factor D, receptor-binding form;
DE              Short=PDGFD receptor-binding form;
DE   Flags: Precursor;
GN   Name=PDGFD; Synonyms=IEGF, SCDGFB; ORFNames=MSTP036, UNQ1899/PRO4345;
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
//
ID   PDGFB_HUMAN             Reviewed;         241 AA.
AC   P01127; G3XAG8; P78431; Q15354; Q6FHE7; Q9UF23;
DE   RecName: Full=Platelet-derived growth factor subunit B;
DE            Short=PDGF subunit B;
DE   AltName: Full=PDGF-2;
DE   AltName: Full=Platelet-derived growth factor B chain;
DE   AltName: Full=Platelet-derived growth factor beta polypeptide;
DE   AltName: Full=Proto-oncogene c-Sis;
DE   AltName: INN=Becaplermin;
DE   Flags: Precursor;
GN   Name=PDGFB; Synonyms=PDGF2, SIS;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:BHF-UCL.
DR   GO; GO:0005518; F:collagen binding; IDA:MGI.
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048514; P:blood vessel morphogenesis; IEA:Ensembl.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0030031; P:cell projection assembly; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0072264; P:metanephric glomerular endothelium development; IEA:Ensembl.
DR   GO; GO:0072255; P:metanephric glomerular mesangial cell development; ISS:UniProtKB.
DR   GO; GO:0072262; P:metanephric glomerular mesangial cell proliferation involved in metanephros development; IEA:Ensembl.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038001; P:paracrine signaling; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; IDA:UniProtKB.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0003104; P:positive regulation of glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0072126; P:positive regulation of glomerular mesangial cell proliferation; IDA:UniProtKB.
DR   GO; GO:1900127; P:positive regulation of hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:2000591; P:positive regulation of metanephric mesenchymal cell migration; IDA:UniProtKB.
DR   GO; GO:0035793; P:positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IDA:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; NAS:UniProtKB.
DR   GO; GO:0006929; P:substrate-dependent cell migration; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
//
ID   PDIA1_HUMAN             Reviewed;         508 AA.
AC   P07237; B2RDQ2; P30037; P32079; Q15205; Q6LDE5;
DE   RecName: Full=Protein disulfide-isomerase;
DE            Short=PDI;
DE            EC=5.3.4.1;
DE   AltName: Full=Cellular thyroid hormone-binding protein;
DE   AltName: Full=Prolyl 4-hydroxylase subunit beta;
DE   AltName: Full=p55;
DE   Flags: Precursor;
GN   Name=P4HB; Synonyms=ERBA2L, PDI, PDIA1, PO4DB;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004656; F:procollagen-proline 4-dioxygenase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0018401; P:peptidyl-proline hydroxylation to 4-hydroxy-L-proline; IDA:MGI.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:1902175; P:regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDIA2_HUMAN             Reviewed;         525 AA.
AC   Q13087; A6ZJ64; B4DI27; Q2WGM4; Q4TT67; Q6B010; Q96KJ6; Q9BW95;
DE   RecName: Full=Protein disulfide-isomerase A2;
DE            EC=5.3.4.1;
DE   AltName: Full=Pancreas-specific protein disulfide isomerase;
DE            Short=PDIp;
DE   Flags: Precursor;
GN   Name=PDIA2; Synonyms=PDIP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0019511; P:peptidyl-proline hydroxylation; IBA:GOC.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.
DR   GO; GO:1902175; P:regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   PDIA3_HUMAN             Reviewed;         505 AA.
AC   P30101; Q13453; Q14255; Q8IYF8; Q9UMU7;
DE   RecName: Full=Protein disulfide-isomerase A3;
DE            EC=5.3.4.1;
DE   AltName: Full=58 kDa glucose-regulated protein;
DE   AltName: Full=58 kDa microsomal protein;
DE            Short=p58;
DE   AltName: Full=Disulfide isomerase ER-60;
DE   AltName: Full=Endoplasmic reticulum resident protein 57;
DE            Short=ER protein 57;
DE            Short=ERp57;
DE   AltName: Full=Endoplasmic reticulum resident protein 60;
DE            Short=ER protein 60;
DE            Short=ERp60;
DE   Flags: Precursor;
GN   Name=PDIA3; Synonyms=ERP57, ERP60, GRP58;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0006606; P:protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:GOC.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PDIA4_HUMAN             Reviewed;         645 AA.
AC   P13667; A8K4K6; Q549T6;
DE   RecName: Full=Protein disulfide-isomerase A4;
DE            EC=5.3.4.1;
DE   AltName: Full=Endoplasmic reticulum resident protein 70;
DE            Short=ER protein 70;
DE            Short=ERp70;
DE   AltName: Full=Endoplasmic reticulum resident protein 72;
DE            Short=ER protein 72;
DE            Short=ERp-72;
DE            Short=ERp72;
DE   Flags: Precursor;
GN   Name=PDIA4; Synonyms=ERP70, ERP72;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; ISS:UniProt.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; ISS:UniProt.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0009306; P:protein secretion; TAS:ProtInc.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   PDIA5_HUMAN             Reviewed;         519 AA.
AC   Q14554; D3DN95;
DE   RecName: Full=Protein disulfide-isomerase A5;
DE            EC=5.3.4.1;
DE   AltName: Full=Protein disulfide isomerase-related protein;
DE   Flags: Precursor;
GN   Name=PDIA5; Synonyms=PDIR;
DR   GO; GO:0016491; F:oxidoreductase activity; TAS:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; TAS:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   PDIA6_HUMAN             Reviewed;         440 AA.
AC   Q15084; B7Z254; Q53RC7; Q6ZSH5; Q99778;
DE   RecName: Full=Protein disulfide-isomerase A6;
DE            EC=5.3.4.1;
DE   AltName: Full=Endoplasmic reticulum protein 5;
DE            Short=ER protein 5;
DE            Short=ERp5;
DE   AltName: Full=Protein disulfide isomerase P5;
DE   AltName: Full=Thioredoxin domain-containing protein 7;
DE   Flags: Precursor;
GN   Name=PDIA6; Synonyms=ERP5, P5, TXNDC7;
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0043277; P:apoptotic cell clearance; IBA:RefGenome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   PDILT_HUMAN             Reviewed;         584 AA.
AC   Q8N807; Q8IVQ5;
DE   RecName: Full=Protein disulfide-isomerase-like protein of the testis;
DE   Flags: Precursor;
GN   Name=PDILT;
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   PDIP2_HUMAN             Reviewed;         368 AA.
AC   Q9Y2S7; B2R846; Q96JE4;
DE   RecName: Full=Polymerase delta-interacting protein 2;
DE   AltName: Full=38 kDa DNA polymerase delta interaction protein;
DE            Short=p38;
GN   Name=POLDIP2; Synonyms=PDIP38, POLD4; ORFNames=HSPC017;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
//
ID   PDIP3_HUMAN             Reviewed;         421 AA.
AC   Q9BY77; A8K6F8; A8K6V9; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9NSP5;
AC   Q9NSP6;
DE   RecName: Full=Polymerase delta-interacting protein 3;
DE   AltName: Full=46 kDa DNA polymerase delta interaction protein;
DE            Short=p46;
DE   AltName: Full=S6K1 Aly/REF-like target;
DE            Short=SKAR;
GN   Name=POLDIP3; Synonyms=KIAA1649, PDIP46;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
//
ID   PDK1L_HUMAN             Reviewed;         341 AA.
AC   Q8N165; B2R777; D3DPK2; Q5T2I0; Q8NDB3;
DE   RecName: Full=Serine/threonine-protein kinase PDIK1L;
DE            EC=2.7.11.1;
DE   AltName: Full=PDLIM1-interacting kinase 1-like;
GN   Name=PDIK1L; Synonyms=CLIK1L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   PDK1_HUMAN              Reviewed;         436 AA.
AC   Q15118; B2R6T1; D3DPD8;
DE   RecName: Full=[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial;
DE            EC=2.7.11.2;
DE   AltName: Full=Pyruvate dehydrogenase kinase isoform 1;
DE            Short=PDH kinase 1;
DE   Flags: Precursor;
GN   Name=PDK1; Synonyms=PDHK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0097411; P:hypoxia-inducible factor-1alpha signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDK2_HUMAN              Reviewed;         407 AA.
AC   Q15119; A8K3A7; B3KNW0; Q6P515; Q9BS05;
DE   RecName: Full=[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial;
DE            EC=2.7.11.2;
DE   AltName: Full=Pyruvate dehydrogenase kinase isoform 2;
DE            Short=PDH kinase 2;
DE            Short=PDKII;
DE   Flags: Precursor;
GN   Name=PDK2; Synonyms=PDHK2;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0031670; P:cellular response to nutrient; ISS:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IMP:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; ISS:UniProtKB.
DR   GO; GO:0010565; P:regulation of cellular ketone metabolic process; ISS:UniProtKB.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; ISS:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0006885; P:regulation of pH; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDK3_HUMAN              Reviewed;         406 AA.
AC   Q15120; B4DXG6;
DE   RecName: Full=[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial;
DE            EC=2.7.11.2;
DE   AltName: Full=Pyruvate dehydrogenase kinase isoform 3;
DE   Flags: Precursor;
GN   Name=PDK3; Synonyms=PDHK3;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0071398; P:cellular response to fatty acid; IMP:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0097411; P:hypoxia-inducible factor-1alpha signaling pathway; IMP:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0035357; P:peroxisome proliferator activated receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; IMP:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IMP:UniProtKB.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDK4_HUMAN              Reviewed;         411 AA.
AC   Q16654;
DE   RecName: Full=[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial;
DE            EC=2.7.11.2;
DE   AltName: Full=Pyruvate dehydrogenase kinase isoform 4;
DE   Flags: Precursor;
GN   Name=PDK4; Synonyms=PDHK4;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004740; F:pyruvate dehydrogenase (acetyl-transferring) kinase activity; ISS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0071398; P:cellular response to fatty acid; IMP:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IDA:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; IMP:UniProtKB.
DR   GO; GO:0045124; P:regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0010565; P:regulation of cellular ketone metabolic process; ISS:UniProtKB.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0046320; P:regulation of fatty acid oxidation; ISS:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; IMP:UniProtKB.
DR   GO; GO:0006885; P:regulation of pH; ISS:UniProtKB.
DR   GO; GO:0042594; P:response to starvation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDLI1_HUMAN             Reviewed;         329 AA.
AC   O00151; B2RBS6; Q5VZH5; Q9BPZ9;
DE   RecName: Full=PDZ and LIM domain protein 1;
DE   AltName: Full=C-terminal LIM domain protein 1;
DE   AltName: Full=Elfin;
DE   AltName: Full=LIM domain protein CLP-36;
GN   Name=PDLIM1; Synonyms=CLIM1, CLP36;
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
//
ID   PDLI2_HUMAN             Reviewed;         352 AA.
AC   Q96JY6; D3DSR5; J3KNH4; Q7Z584; Q86WM8; Q8WZ29; Q9H4L9; Q9H7I2;
DE   RecName: Full=PDZ and LIM domain protein 2;
DE   AltName: Full=PDZ-LIM protein mystique;
GN   Name=PDLIM2; ORFNames=PP6345;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PDLI3_HUMAN             Reviewed;         364 AA.
AC   Q53GG5; B2R866; O43590; O60439; O60440; Q8N6Y6; Q9BVP4;
DE   RecName: Full=PDZ and LIM domain protein 3;
DE   AltName: Full=Actinin-associated LIM protein;
DE   AltName: Full=Alpha-actinin-2-associated LIM protein;
GN   Name=PDLIM3; Synonyms=ALP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008307; F:structural constituent of muscle; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
//
ID   PDLI4_HUMAN             Reviewed;         330 AA.
AC   P50479; B2R8U1; Q53Y39; Q96AT8; Q9BTW8; Q9Y292;
DE   RecName: Full=PDZ and LIM domain protein 4;
DE   AltName: Full=LIM protein RIL;
DE   AltName: Full=Reversion-induced LIM protein;
GN   Name=PDLIM4; Synonyms=RIL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PDLI5_HUMAN             Reviewed;         596 AA.
AC   Q96HC4; A8K6F9; D6RB78; E9PBF5; O60705; Q56VN4; Q5UW38; Q8WVK0;
DE   RecName: Full=PDZ and LIM domain protein 5;
DE   AltName: Full=Enigma homolog;
DE   AltName: Full=Enigma-like PDZ and LIM domains protein;
GN   Name=PDLIM5; Synonyms=ENH; ORFNames=L9;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0042805; F:actinin binding; ISS:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
//
ID   PDLI7_HUMAN             Reviewed;         457 AA.
AC   Q9NR12; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9;
DE   RecName: Full=PDZ and LIM domain protein 7;
DE   AltName: Full=LIM mineralization protein;
DE            Short=LMP;
DE   AltName: Full=Protein enigma;
GN   Name=PDLIM7; Synonyms=ENIGMA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
//
ID   PDP1_HUMAN              Reviewed;         537 AA.
AC   Q9P0J1; B3KX71; J3KPU0; Q5U5K1;
DE   RecName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial;
DE            Short=PDP 1;
DE            EC=3.1.3.43;
DE   AltName: Full=Protein phosphatase 2C;
DE   AltName: Full=Pyruvate dehydrogenase phosphatase catalytic subunit 1;
DE            Short=PDPC 1;
DE   Flags: Precursor;
GN   Name=PDP1; Synonyms=PDP, PPM2C;
DR   GO; GO:0004741; F:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDP2_HUMAN              Reviewed;         529 AA.
AC   Q9P2J9; A8K924;
DE   RecName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial;
DE            Short=PDP 2;
DE            EC=3.1.3.43;
DE   AltName: Full=Pyruvate dehydrogenase phosphatase catalytic subunit 2;
DE            Short=PDPC 2;
DE   Flags: Precursor;
GN   Name=PDP2; Synonyms=KIAA1348;
DR   GO; GO:0004741; F:[pyruvate dehydrogenase (lipoamide)] phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDPFL_HUMAN             Reviewed;          84 AA.
AC   Q8WWR9; G3V137; Q8WVI1;
DE   RecName: Full=Pancreatic progenitor cell differentiation and proliferation factor-like protein;
DE   AltName: Full=Exocrine differentiation and proliferation factor-like protein;
GN   Name=C8orf22;
//
ID   PDPK1_HUMAN             Reviewed;         556 AA.
AC   O15530; H0Y4Z0; Q59EH6; Q6FI20; Q8IV52; Q9BRD5;
DE   RecName: Full=3-phosphoinositide-dependent protein kinase 1;
DE            Short=hPDK1;
DE            EC=2.7.11.1;
GN   Name=PDPK1; Synonyms=PDK1;
DR   GuidetoPHARMACOLOGY; 1519; -.
DR   GO; GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:MGI.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010594; P:regulation of endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0043304; P:regulation of mast cell degranulation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0003323; P:type B pancreatic cell development; IEA:Ensembl.
//
ID   PDPK2_HUMAN             Reviewed;         396 AA.
AC   Q6A1A2;
DE   RecName: Full=Putative 3-phosphoinositide-dependent protein kinase 2;
DE            EC=2.7.11.1;
GN   Name=PDPK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   PDPN_HUMAN              Reviewed;         162 AA.
AC   Q86YL7; A9Z1Y2; B2R6J8; E9PB68; F6QWX5; O60836; O95128; Q7L375;
AC   Q8NBQ8; Q8NBR3;
DE   RecName: Full=Podoplanin;
DE   AltName: Full=Aggrus;
DE   AltName: Full=Glycoprotein 36;
DE            Short=Gp36;
DE   AltName: Full=PA2.26 antigen;
DE   AltName: Full=T1-alpha;
DE            Short=T1A;
DE   Flags: Precursor;
GN   Name=PDPN; Synonyms=GP36; ORFNames=PSEC0003, PSEC0025;
DR   GO; GO:0000902; P:cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; ISS:UniProtKB.
DR   GO; GO:0001946; P:lymphangiogenesis; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; ISS:UniProtKB.
DR   GO; GO:0010572; P:positive regulation of platelet activation; IEA:Ensembl.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0035239; P:tube morphogenesis; IEA:Ensembl.
//
ID   PDPR_HUMAN              Reviewed;         879 AA.
AC   Q8NCN5; A7E298; A8K8Y7; Q6AI20; Q6AWC9;
DE   RecName: Full=Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial;
DE            Short=PDPr;
DE   Flags: Precursor;
GN   Name=PDPR; Synonyms=KIAA1990;
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006546; P:glycine catabolic process; IEA:InterPro.
DR   GO; GO:0006090; P:pyruvate metabolic process; TAS:Reactome.
DR   GO; GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PDRG1_HUMAN             Reviewed;         133 AA.
AC   Q9NUG6; B2R511; Q96GP3; Q9BUW8;
DE   RecName: Full=p53 and DNA damage-regulated protein 1;
GN   Name=PDRG1; Synonyms=C20orf126, PDRG;
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   PDS5A_HUMAN             Reviewed;        1337 AA.
AC   Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4;
DE   RecName: Full=Sister chromatid cohesion protein PDS5 homolog A;
DE   AltName: Full=Cell proliferation-inducing gene 54 protein;
DE   AltName: Full=Sister chromatid cohesion protein 112;
DE            Short=SCC-112;
GN   Name=PDS5A; Synonyms=KIAA0648, PDS5; ORFNames=PIG54;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.
//
ID   PDS5B_HUMAN             Reviewed;        1447 AA.
AC   Q9NTI5; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9Y2I5; Q9Y451;
DE   RecName: Full=Sister chromatid cohesion protein PDS5 homolog B;
DE   AltName: Full=Androgen-induced proliferation inhibitor;
DE   AltName: Full=Androgen-induced prostate proliferative shutoff-associated protein AS3;
GN   Name=PDS5B; Synonyms=APRIN, AS3, KIAA0979;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:MGI.
//
ID   PDX1_HUMAN              Reviewed;         283 AA.
AC   P52945; O60594; Q5VYW2;
DE   RecName: Full=Pancreas/duodenum homeobox protein 1;
DE            Short=PDX-1;
DE   AltName: Full=Glucose-sensitive factor;
DE            Short=GSF;
DE   AltName: Full=Insulin promoter factor 1;
DE            Short=IPF-1;
DE   AltName: Full=Insulin upstream factor 1;
DE            Short=IUF-1;
DE   AltName: Full=Islet/duodenum homeobox-1;
DE            Short=IDX-1;
DE   AltName: Full=Somatostatin-transactivating factor 1;
DE            Short=STF-1;
GN   Name=PDX1; Synonyms=IPF1, STF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0051594; P:detection of glucose; ISS:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IDA:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0010260; P:organ senescence; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0010157; P:response to chlorate; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0010040; P:response to iron(II) ion; IEA:Ensembl.
DR   GO; GO:0043201; P:response to leucine; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0033273; P:response to vitamin; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0060290; P:transdifferentiation; IEA:Ensembl.
DR   GO; GO:0003309; P:type B pancreatic cell differentiation; IDA:BHF-UCL.
//
ID   PDXD1_HUMAN             Reviewed;         788 AA.
AC   Q6P996; O00236; Q4F6X7; Q6PID7; Q86YF1; Q8N4Q9; Q8TBS5;
DE   RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1;
DE            EC=4.1.1.-;
GN   Name=PDXDC1; Synonyms=KIAA0251;
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
//
ID   PDXD2_HUMAN             Reviewed;         469 AA.
AC   Q6P474; A8K9Z5;
DE   RecName: Full=Putative pyridoxal-dependent decarboxylase domain-containing protein 2;
DE            EC=4.1.1.-;
DE   AltName: Full=pyridoxal-dependent decarboxylase domain-containing 2 pseudogene;
GN   Name=PDXDC2P; Synonyms=PDXDC2;
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
//
ID   PDXK_HUMAN              Reviewed;         312 AA.
AC   O00764; Q7Z2Y0; Q9BS02;
DE   RecName: Full=Pyridoxal kinase;
DE            EC=2.7.1.35;
DE   AltName: Full=Pyridoxine kinase;
GN   Name=PDXK; Synonyms=C21orf124, C21orf97, PKH, PNK; ORFNames=PRED79;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0031403; F:lithium ion binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030955; F:potassium ion binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008478; F:pyridoxal kinase activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0031402; F:sodium ion binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0009443; P:pyridoxal 5'-phosphate salvage; IEA:InterPro.
DR   GO; GO:0042823; P:pyridoxal phosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042816; P:vitamin B6 metabolic process; IC:UniProtKB.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PDXL2_HUMAN             Reviewed;         605 AA.
AC   Q9NZ53; Q6UVY4; Q8WUV6;
DE   RecName: Full=Podocalyxin-like protein 2;
DE   AltName: Full=Endoglycan;
DE   Flags: Precursor;
GN   Name=PODXL2; ORFNames=UNQ1861/PRO3742;
DR   GO; GO:0005539; F:glycosaminoglycan binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IDA:UniProtKB.
//
ID   PDYN_HUMAN              Reviewed;         254 AA.
AC   P01213; A8K0Q3;
DE   RecName: Full=Proenkephalin-B;
DE   AltName: Full=Beta-neoendorphin-dynorphin;
DE   AltName: Full=Preprodynorphin;
DE   Contains:
DE     RecName: Full=Alpha-neoendorphin;
DE   Contains:
DE     RecName: Full=Beta-neoendorphin;
DE   Contains:
DE     RecName: Full=Big dynorphin;
DE              Short=Big Dyn;
DE   Contains:
DE     RecName: Full=Dynorphin A(1-17);
DE              Short=Dyn-A17;
DE              Short=Dynorphin A;
DE   Contains:
DE     RecName: Full=Dynorphin A(1-13);
DE   Contains:
DE     RecName: Full=Dynorphin A(1-8);
DE   Contains:
DE     RecName: Full=Leu-enkephalin;
DE   Contains:
DE     RecName: Full=Rimorphin;
DE     AltName: Full=Dynorphin B;
DE              Short=Dyn-B;
DE     AltName: Full=Dynorphin B(1-13);
DE   Contains:
DE     RecName: Full=Leumorphin;
DE     AltName: Full=Dynorphin B-29;
DE   Flags: Precursor;
GN   Name=PDYN;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; IEA:UniProtKB-KW.
//
ID   PDZ11_HUMAN             Reviewed;         140 AA.
AC   Q5EBL8; D3DVU3; Q6UWE1; Q9P0Q1;
DE   RecName: Full=PDZ domain-containing protein 11;
DE   AltName: Full=ATPase-interacting PDZ protein;
DE   AltName: Full=Plasma membrane calcium ATPase-interacting single-PDZ protein;
DE            Short=PMCA-interacting single-PDZ protein;
GN   Name=PDZD11; Synonyms=AIPP1, PDZK11, PISP;
GN   ORFNames=HSPC227, UNQ6486/PRO21335;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
//
ID   PDZD2_HUMAN             Reviewed;        2839 AA.
AC   O15018; Q9BXD4;
DE   RecName: Full=PDZ domain-containing protein 2;
DE   AltName: Full=Activated in prostate cancer protein;
DE   AltName: Full=PDZ domain-containing protein 3;
DE   Contains:
DE     RecName: Full=Processed PDZ domain-containing protein 2;
GN   Name=PDZD2; Synonyms=AIPC, KIAA0300, PDZK3;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   PDZ1P_HUMAN             Reviewed;         402 AA.
AC   A8MUH7;
DE   RecName: Full=Putative PDZ domain-containing protein 1P;
GN   Name=PDZK1P1;
GN   and
GN   Name=PDZK1P2;
//
ID   PDZ1I_HUMAN             Reviewed;         114 AA.
AC   Q13113; Q6ICT9; Q96EI1;
DE   RecName: Full=PDZK1-interacting protein 1;
DE   AltName: Full=17 kDa membrane-associated protein;
DE   AltName: Full=Protein DD96;
GN   Name=PDZK1IP1; Synonyms=MAP17;
//
ID   PDZD7_HUMAN             Reviewed;         517 AA.
AC   Q9H5P4; D5FJ77; Q8N321;
DE   RecName: Full=PDZ domain-containing protein 7;
GN   Name=PDZD7; Synonyms=PDZK7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   PDZD4_HUMAN             Reviewed;         769 AA.
AC   Q76G19; B3KXB1; B7ZKY3; Q8NB75; Q9BUH9; Q9P284;
DE   RecName: Full=PDZ domain-containing protein 4;
DE   AltName: Full=PDZ domain-containing RING finger protein 4-like protein;
GN   Name=PDZD4; Synonyms=KIAA1444, PDZK4, PDZRN4L;
//
ID   PDZD9_HUMAN             Reviewed;         264 AA.
AC   Q8IXQ8; F5GWW8;
DE   RecName: Full=PDZ domain-containing protein 9;
GN   Name=PDZD9; Synonyms=C16orf65;
//
ID   PDZD8_HUMAN             Reviewed;        1154 AA.
AC   Q8NEN9; Q86WE0; Q86WE5; Q9UFF1;
DE   RecName: Full=PDZ domain-containing protein 8;
DE   AltName: Full=Sarcoma antigen NY-SAR-84/NY-SAR-104;
GN   Name=PDZD8; Synonyms=PDZK8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PE2R1_HUMAN             Reviewed;         402 AA.
AC   P34995; Q5U5U4; Q86UH3; Q86VB5; Q8NHB2;
DE   RecName: Full=Prostaglandin E2 receptor EP1 subtype;
DE            Short=PGE receptor EP1 subtype;
DE            Short=PGE2 receptor EP1 subtype;
DE   AltName: Full=Prostanoid EP1 receptor;
GN   Name=PTGER1;
DR   GuidetoPHARMACOLOGY; 340; -.
DR   GO; GO:0004957; F:prostaglandin E receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   PE2R2_HUMAN             Reviewed;         358 AA.
AC   P43116; D3DSC0; Q52LG8;
DE   RecName: Full=Prostaglandin E2 receptor EP2 subtype;
DE            Short=PGE receptor EP2 subtype;
DE            Short=PGE2 receptor EP2 subtype;
DE   AltName: Full=Prostanoid EP2 receptor;
GN   Name=PTGER2;
DR   GuidetoPHARMACOLOGY; 341; -.
DR   GO; GO:0004957; F:prostaglandin E receptor activity; TAS:ProtInc.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; ISS:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   PE2R3_HUMAN             Reviewed;         390 AA.
AC   P43115; B0AZN4; B5BUP5; O00326; Q12943; Q12944; Q12945; Q16546;
AC   Q5CZ59; Q5CZ62; Q5CZ63; Q5CZ64;
DE   RecName: Full=Prostaglandin E2 receptor EP3 subtype;
DE            Short=PGE receptor EP3 subtype;
DE            Short=PGE2 receptor EP3 subtype;
DE   AltName: Full=PGE2-R;
DE   AltName: Full=Prostanoid EP3 receptor;
GN   Name=PTGER3;
DR   GuidetoPHARMACOLOGY; 342; -.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004957; F:prostaglandin E receptor activity; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0031622; P:positive regulation of fever generation; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   PE2R4_HUMAN             Reviewed;         488 AA.
AC   P35408; Q3MJ87;
DE   RecName: Full=Prostaglandin E2 receptor EP4 subtype;
DE            Short=PGE receptor EP4 subtype;
DE            Short=PGE2 receptor EP4 subtype;
DE   AltName: Full=Prostanoid EP4 receptor;
GN   Name=PTGER4; Synonyms=PTGER2;
DR   GuidetoPHARMACOLOGY; 343; -.
DR   GO; GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060348; P:bone development; ISS:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEP:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; ISS:UniProtKB.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:2000420; P:negative regulation of eosinophil extravasation; IDA:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:0033624; P:negative regulation of integrin activation; IDA:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0030278; P:regulation of ossification; IEA:Ensembl.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; ISS:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0042093; P:T-helper cell differentiation; ISS:UniProtKB.
//
ID   PEA15_HUMAN             Reviewed;         130 AA.
AC   Q15121; O00511;
DE   RecName: Full=Astrocytic phosphoprotein PEA-15;
DE   AltName: Full=15 kDa phosphoprotein enriched in astrocytes;
DE   AltName: Full=Phosphoprotein enriched in diabetes;
DE            Short=PED;
GN   Name=PEA15;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProtKB.
DR   GO; GO:0046325; P:negative regulation of glucose import; IDA:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   PEAK1_HUMAN             Reviewed;        1746 AA.
AC   Q9H792; Q6ZS78; Q8NAZ4; Q8NCM3; Q8TEG7;
DE   RecName: Full=Pseudopodium-enriched atypical kinase 1;
DE            EC=2.7.10.2;
DE   AltName: Full=Sugen kinase 269;
DE   AltName: Full=Tyrosine-protein kinase SgK269;
GN   Name=PEAK1; Synonyms=KIAA2002;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.
//
ID   PEAR1_HUMAN             Reviewed;        1037 AA.
AC   Q5VY43; Q8TEK2;
DE   RecName: Full=Platelet endothelial aggregation receptor 1;
DE            Short=hPEAR1;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 12;
DE            Short=Multiple EGF-like domains protein 12;
DE   Flags: Precursor;
GN   Name=PEAR1; Synonyms=MEGF12;
DR   GO; GO:0043654; P:recognition of apoptotic cell; IEA:Ensembl.
//
ID   PEBB_HUMAN              Reviewed;         182 AA.
AC   Q13951; A8K347; Q13124; Q9HCT2;
DE   RecName: Full=Core-binding factor subunit beta;
DE            Short=CBF-beta;
DE   AltName: Full=Polyomavirus enhancer-binding protein 2 beta subunit;
DE            Short=PEA2-beta;
DE            Short=PEBP2-beta;
DE   AltName: Full=SL3-3 enhancer factor 1 subunit beta;
DE   AltName: Full=SL3/AKV core-binding factor beta subunit;
GN   Name=CBFB;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0030098; P:lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030099; P:myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PEBP1_HUMAN             Reviewed;         187 AA.
AC   P30086; B2R4S1;
DE   RecName: Full=Phosphatidylethanolamine-binding protein 1;
DE            Short=PEBP-1;
DE   AltName: Full=HCNPpp;
DE   AltName: Full=Neuropolypeptide h3;
DE   AltName: Full=Prostatic-binding protein;
DE   AltName: Full=Raf kinase inhibitor protein;
DE            Short=RKIP;
DE   Contains:
DE     RecName: Full=Hippocampal cholinergic neurostimulating peptide;
DE              Short=HCNP;
GN   Name=PEBP1; Synonyms=PBP, PEBP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0008429; F:phosphatidylethanolamine binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   PEBP4_HUMAN             Reviewed;         227 AA.
AC   Q96S96; Q5EVA1; Q8WW74;
DE   RecName: Full=Phosphatidylethanolamine-binding protein 4;
DE            Short=PEBP-4;
DE            Short=hPEBP4;
DE   AltName: Full=Protein cousin-of-RKIP 1;
DE   Flags: Precursor;
GN   Name=PEBP4; Synonyms=CORK1; ORFNames=UNQ1933/PRO4408;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PECA1_HUMAN             Reviewed;         738 AA.
AC   P16284; A8K3S7; D3DU31; Q6LDA9; Q8TBH1; Q96RF5; Q96RF6; Q9NP65;
AC   Q9NPB7; Q9NPG9; Q9NQS9; Q9NQT0; Q9NQT1; Q9NQT2;
DE   RecName: Full=Platelet endothelial cell adhesion molecule;
DE            Short=PECAM-1;
DE   AltName: Full=EndoCAM;
DE   AltName: Full=GPIIA';
DE   AltName: Full=PECA1;
DE   AltName: CD_antigen=CD31;
DE   Flags: Precursor;
GN   Name=PECAM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008037; P:cell recognition; TAS:ProtInc.
DR   GO; GO:0050904; P:diapedesis; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0072011; P:glomerular endothelium development; IEP:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0006909; P:phagocytosis; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PECR_HUMAN              Reviewed;         303 AA.
AC   Q9BY49; B2RE42; Q53TC4; Q6IAK9; Q9NRD4; Q9NY60; Q9P1A4;
DE   RecName: Full=Peroxisomal trans-2-enoyl-CoA reductase;
DE            Short=TERP;
DE            EC=1.3.1.38;
DE   AltName: Full=2,4-dienoyl-CoA reductase-related protein;
DE            Short=DCR-RP;
DE   AltName: Full=HPDHase;
DE   AltName: Full=pVI-ARL;
GN   Name=PECR; ORFNames=PRO1004;
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0033306; P:phytol metabolic process; IDA:UniProtKB.
//
ID   PED1B_HUMAN             Reviewed;         432 AA.
AC   Q96HM7; Q96B20;
DE   RecName: Full=PC-esterase domain-containing protein 1B;
DE   AltName: Full=Protein FAM113B;
GN   Name=PCED1B; Synonyms=FAM113B;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
//
ID   PED1A_HUMAN             Reviewed;         454 AA.
AC   Q9H1Q7; Q5JUA5; Q5JUA6; Q6PK19; Q86WF5; Q96CG7; Q9H1Q6; Q9H6D1;
DE   RecName: Full=PC-esterase domain-containing protein 1A;
DE   AltName: Full=Protein FAM113A;
DE   AltName: Full=Sarcoma antigen NY-SAR-23;
GN   Name=PCED1A; Synonyms=C20orf81, FAM113A;
//
ID   PEDF_HUMAN              Reviewed;         418 AA.
AC   P36955; F1T092; Q13236; Q2TU83; Q96CT1; Q96R01; Q9BWA4;
DE   RecName: Full=Pigment epithelium-derived factor;
DE            Short=PEDF;
DE   AltName: Full=Cell proliferation-inducing gene 35 protein;
DE   AltName: Full=EPC-1;
DE   AltName: Full=Serpin F1;
DE   Flags: Precursor;
GN   Name=SERPINF1; Synonyms=PEDF; ORFNames=PIG35;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IDA:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007614; P:short-term memory; IEA:Ensembl.
//
ID   PEF1_HUMAN              Reviewed;         284 AA.
AC   Q9UBV8;
DE   RecName: Full=Peflin;
DE   AltName: Full=PEF protein with a long N-terminal hydrophobic domain;
DE   AltName: Full=Penta-EF hand domain-containing protein 1;
GN   Name=PEF1; Synonyms=ABP32; ORFNames=UNQ1845/PRO3573;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0051592; P:response to calcium ion; IPI:UniProtKB.
//
ID   PEG10_HUMAN             Reviewed;         708 AA.
AC   Q86TG7; Q96A68; Q9UPV1;
DE   RecName: Full=Retrotransposon-derived protein PEG10;
DE   AltName: Full=Embryonal carcinoma differentiation-regulated protein;
DE   AltName: Full=Mammalian retrotransposon-derived protein 2;
DE   AltName: Full=Myelin expression factor 3-like protein 1;
DE            Short=MEF3-like protein 1;
DE   AltName: Full=Paternally expressed gene 10 protein;
DE   AltName: Full=Retrotransposon gag domain-containing protein 3;
DE   AltName: Full=Retrotransposon-derived gag-like polyprotein;
DE   AltName: Full=Ty3/Gypsy-like protein;
GN   Name=PEG10; Synonyms=EDR, KIAA1051, MAR2, MART2, MEF3L1, RGAG3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
//
ID   PEG3_HUMAN              Reviewed;        1588 AA.
AC   Q9GZU2; A7E2B8; B4DIM4; C9JP50; P78418; Q5H9P9; Q7Z7H7; Q8TF75;
AC   Q9GZY2;
DE   RecName: Full=Paternally-expressed gene 3 protein;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 24;
GN   Name=PEG3; Synonyms=KIAA0287, ZSCAN24;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071514; P:genetic imprinting; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   PELI2_HUMAN             Reviewed;         420 AA.
AC   Q9HAT8; B2RDY5;
DE   RecName: Full=E3 ubiquitin-protein ligase pellino homolog 2;
DE            Short=Pellino-2;
DE            EC=6.3.2.-;
GN   Name=PELI2;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008063; P:Toll signaling pathway; IEA:InterPro.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   PELI1_HUMAN             Reviewed;         418 AA.
AC   Q96FA3; Q96SM0; Q9GZY5; Q9HCX0;
DE   RecName: Full=E3 ubiquitin-protein ligase pellino homolog 1;
DE            Short=Pellino-1;
DE            EC=6.3.2.-;
DE   AltName: Full=Pellino-related intracellular-signaling molecule;
GN   Name=PELI1; Synonyms=PRISM;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0034141; P:positive regulation of toll-like receptor 3 signaling pathway; IEA:Ensembl.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IEA:Ensembl.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IEA:Ensembl.
DR   GO; GO:0043331; P:response to dsRNA; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0008063; P:Toll signaling pathway; IEA:InterPro.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   PELI3_HUMAN             Reviewed;         469 AA.
AC   Q8N2H9; Q8N3E1; Q8N9Q6; Q8TAW7; Q8TED5;
DE   RecName: Full=E3 ubiquitin-protein ligase pellino homolog 3;
DE            Short=Pellino-3;
DE            EC=6.3.2.-;
GN   Name=PELI3;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:MGI.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IMP:MGI.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008063; P:Toll signaling pathway; IEA:InterPro.
//
ID   PELO_HUMAN              Reviewed;         385 AA.
AC   Q9BRX2; Q9GZS6; Q9Y306;
DE   RecName: Full=Protein pelota homolog;
DE            EC=3.1.-.-;
GN   Name=PELO; ORFNames=CGI-17;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
//
ID   PELP1_HUMAN             Reviewed;        1130 AA.
AC   Q8IZL8; O15450; Q5EGN3; Q6NTE6; Q96FT1; Q9BU60;
DE   RecName: Full=Proline-, glutamic acid- and leucine-rich protein 1;
DE   AltName: Full=Modulator of non-genomic activity of estrogen receptor;
DE   AltName: Full=Transcription factor HMX3;
GN   Name=PELP1; Synonyms=HMX3, MNAR;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PEMT_HUMAN              Reviewed;         199 AA.
AC   Q9UBM1; A8MZ66; B4DY41; D3DXC3; Q6IAQ5; Q86VL3; Q9BW86; Q9UHY6;
AC   Q9Y6V9;
DE   RecName: Full=Phosphatidylethanolamine N-methyltransferase;
DE            Short=PEAMT;
DE            Short=PEMT;
DE            EC=2.1.1.17;
DE            EC=2.1.1.71;
DE   AltName: Full=PEMT2;
GN   Name=PEMT; Synonyms=PEMPT, PNMT;
DR   GO; GO:0080101; F:phosphatidyl-N-dimethylethanolamine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000773; F:phosphatidyl-N-methylethanolamine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004608; F:phosphatidylethanolamine N-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PEN2_HUMAN              Reviewed;         101 AA.
AC   Q9NZ42; B2R5L9;
DE   RecName: Full=Gamma-secretase subunit PEN-2;
DE   AltName: Full=Presenilin enhancer protein 2;
GN   Name=PSENEN; Synonyms=PEN2; ORFNames=MDS033;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; TAS:HGNC.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:HGNC.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:HGNC.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:HGNC.
DR   GO; GO:0016485; P:protein processing; IDA:HGNC.
//
ID   PENK_HUMAN              Reviewed;         267 AA.
AC   P01210; B2RC23; Q6FHC6; Q6FHE6;
DE   RecName: Full=Proenkephalin-A;
DE   Contains:
DE     RecName: Full=Synenkephalin;
DE   Contains:
DE     RecName: Full=Met-enkephalin;
DE     AltName: Full=Opioid growth factor;
DE              Short=OGF;
DE   Contains:
DE     RecName: Full=PENK(114-133);
DE   Contains:
DE     RecName: Full=PENK(143-183);
DE   Contains:
DE     RecName: Full=Met-enkephalin-Arg-Gly-Leu;
DE   Contains:
DE     RecName: Full=Leu-enkephalin;
DE   Contains:
DE     RecName: Full=PENK(237-258);
DE   Contains:
DE     RecName: Full=Met-enkephalin-Arg-Phe;
DE   Flags: Precursor;
GN   Name=PENK;
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002118; P:aggressive behavior; IEA:Ensembl.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
//
ID   PEO1_HUMAN              Reviewed;         684 AA.
AC   Q96RR1; B2CQL2; Q6MZX2; Q6PJP5; Q96RR0;
DE   RecName: Full=Twinkle protein, mitochondrial;
DE            EC=3.6.4.12;
DE   AltName: Full=Progressive external ophthalmoplegia 1 protein;
DE   AltName: Full=T7 gp4-like protein with intramitochondrial nucleoid localization;
DE   AltName: Full=T7-like mitochondrial DNA helicase;
DE   Flags: Precursor;
GN   Name=PEO1; Synonyms=C10orf2;
DR   GO; GO:0043139; F:5'-3' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:Ensembl.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IMP:UniProtKB.
DR   GO; GO:0034214; P:protein hexamerization; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IMP:UniProtKB.
//
ID   PEPA3_HUMAN             Reviewed;         388 AA.
AC   P0DJD8; A8K749; B2R7D6; B7ZW75; P00790; Q7M4R0; Q8N1E3;
DE   RecName: Full=Pepsin A-3;
DE            EC=3.4.23.1;
DE   AltName: Full=Pepsinogen-3;
DE   Flags: Precursor;
GN   Name=PGA3;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
//
ID   PEPA4_HUMAN             Reviewed;         388 AA.
AC   P0DJD7; A8K749; B7ZW75; P00790; Q7M4R0; Q8N1E3;
DE   RecName: Full=Pepsin A-4;
DE            EC=3.4.23.1;
DE   AltName: Full=Pepsinogen-4;
DE   Flags: Precursor;
GN   Name=PGA4;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
//
ID   PEPA5_HUMAN             Reviewed;         388 AA.
AC   P0DJD9; A8K749; B7ZW62; B7ZW75; P00790; Q7M4R0; Q8N1E3;
DE   RecName: Full=Pepsin A-5;
DE            EC=3.4.23.1;
DE   AltName: Full=Pepsinogen-5;
DE   Flags: Precursor;
GN   Name=PGA5;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
//
ID   PEPC_HUMAN              Reviewed;         388 AA.
AC   P20142; B4DVZ3; Q5T3D7; Q5T3D8;
DE   RecName: Full=Gastricsin;
DE            EC=3.4.23.3;
DE   AltName: Full=Pepsinogen C;
DE   Flags: Precursor;
GN   Name=PGC;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   PEPD_HUMAN              Reviewed;         493 AA.
AC   P12955; A8K3Z1; A8K416; A8K696; A8MX47; B4DDB7; B4DGJ1; E9PCE8;
AC   Q8TBN9; Q9BT75;
DE   RecName: Full=Xaa-Pro dipeptidase;
DE            Short=X-Pro dipeptidase;
DE            EC=3.4.13.9;
DE   AltName: Full=Imidodipeptidase;
DE   AltName: Full=Peptidase D;
DE   AltName: Full=Proline dipeptidase;
DE            Short=Prolidase;
GN   Name=PEPD; Synonyms=PRD;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:InterPro.
DR   GO; GO:0016805; F:dipeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0004181; F:metallocarboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   PEPL1_HUMAN             Reviewed;         523 AA.
AC   Q8NDH3; A6NGZ0; B4DMW7; B7ZBN0; E9PN47; G5EA34; Q53G37; Q5W083;
AC   Q8TF28; Q8WUI2; Q9H1T6; Q9HAI5;
DE   RecName: Full=Probable aminopeptidase NPEPL1;
DE            EC=3.4.11.-;
DE   AltName: Full=Aminopeptidase-like 1;
GN   Name=NPEPL1; Synonyms=KIAA1974;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
//
ID   PEPL_HUMAN              Reviewed;        1756 AA.
AC   O60437; O60314; O60454; Q14C98;
DE   RecName: Full=Periplakin;
DE   AltName: Full=190 kDa paraneoplastic pemphigus antigen;
DE   AltName: Full=195 kDa cornified envelope precursor protein;
GN   Name=PPL; Synonyms=KIAA0568;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   PER1_HUMAN              Reviewed;        1290 AA.
AC   O15534; B2RPA8; D3DTR3;
DE   RecName: Full=Period circadian protein homolog 1;
DE            Short=hPER1;
DE   AltName: Full=Circadian clock protein PERIOD 1;
DE   AltName: Full=Circadian pacemaker protein Rigui;
GN   Name=PER1; Synonyms=KIAA0482, PER, RIGUI;
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0009649; P:entrainment of circadian clock; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0042634; P:regulation of hair cycle; IMP:UniProtKB.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PER2_HUMAN              Reviewed;        1255 AA.
AC   O15055; A2I2P7; Q4ZG49; Q9UQ45;
DE   RecName: Full=Period circadian protein homolog 2;
DE            Short=hPER2;
DE   AltName: Full=Circadian clock protein PERIOD 2;
GN   Name=PER2; Synonyms=KIAA0347;
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0000989; F:transcription factor binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0007623; P:circadian rhythm; TAS:ProtInc.
DR   GO; GO:0042754; P:negative regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0050767; P:regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PER3_HUMAN              Reviewed;        1201 AA.
AC   P56645; Q5H8X4; Q5H8X5; Q969K6; Q96S77; Q96S78; Q9C0J3; Q9NSP9;
AC   Q9UGU8;
DE   RecName: Full=Period circadian protein homolog 3;
DE            Short=hPER3;
DE   AltName: Full=Cell growth-inhibiting gene 13 protein;
DE   AltName: Full=Circadian clock protein PERIOD 3;
GN   Name=PER3; ORFNames=GIG13;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0032922; P:circadian regulation of gene expression; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PERF_HUMAN              Reviewed;         555 AA.
AC   P14222; B2R6X4; Q59F57; Q86WX7;
DE   RecName: Full=Perforin-1;
DE            Short=P1;
DE   AltName: Full=Cytolysin;
DE   AltName: Full=Lymphocyte pore-forming protein;
DE            Short=PFP;
DE   Flags: Precursor;
GN   Name=PRF1; Synonyms=PFP;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0022829; F:wide pore channel activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0019835; P:cytolysis; ISS:UniProtKB.
DR   GO; GO:0002357; P:defense response to tumor cell; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0002418; P:immune response to tumor cell; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; IDA:GOC.
//
ID   PERE_HUMAN              Reviewed;         715 AA.
AC   P11678; Q4TVP3;
DE   RecName: Full=Eosinophil peroxidase;
DE            Short=EPO;
DE            EC=1.11.1.7;
DE   Contains:
DE     RecName: Full=Eosinophil peroxidase light chain;
DE   Contains:
DE     RecName: Full=Eosinophil peroxidase heavy chain;
DE   Flags: Precursor;
GN   Name=EPX; Synonyms=EPER, EPO, EPP;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; TAS:ProtInc.
DR   GO; GO:0002215; P:defense response to nematode; IEA:Ensembl.
DR   GO; GO:0072677; P:eosinophil migration; IEA:Ensembl.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0032693; P:negative regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032714; P:negative regulation of interleukin-5 production; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
//
ID   PERI_HUMAN              Reviewed;         470 AA.
AC   P41219; Q8N577;
DE   RecName: Full=Peripherin;
DE   AltName: Full=Neurofilament 4;
GN   Name=PRPH; Synonyms=NEF4, PRPH1;
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:Ensembl.
//
ID   PERM1_HUMAN             Reviewed;         790 AA.
AC   Q5SV97; Q6ZVZ7; Q9BRF2; S5G239;
DE   RecName: Full=PGC-1 and ERR-induced regulator in muscle protein 1;
DE   AltName: Full=PPARGC1 and ESRR-induced regulator in muscle 1;
DE   AltName: Full=Peroxisome proliferator-activated receptor gamma coactivator 1 and estrogen-related receptor-induced regulator in muscle 1;
GN   Name=PERM1; Synonyms=C1orf170;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0014850; P:response to muscle activity; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PERL_HUMAN              Reviewed;         712 AA.
AC   P22079; A5JUY4; E7EMJ3; Q13408; Q3KNQ2;
DE   RecName: Full=Lactoperoxidase;
DE            Short=LPO;
DE            EC=1.11.1.7;
DE   AltName: Full=Salivary peroxidase;
DE            Short=SPO;
DE   Flags: Precursor;
GN   Name=LPO; Synonyms=SAPX;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036393; F:thiocyanate peroxidase activity; IDA:UniProt.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProt.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006979; P:response to oxidative stress; NAS:UniProtKB.
DR   GO; GO:0018969; P:thiocyanate metabolic process; IDA:GOC.
//
ID   PERM_HUMAN              Reviewed;         745 AA.
AC   P05164; A1L4B8; Q14862; Q4PJH5; Q9UCL7;
DE   RecName: Full=Myeloperoxidase;
DE            Short=MPO;
DE            EC=1.11.2.2;
DE   Contains:
DE     RecName: Full=Myeloperoxidase;
DE   Contains:
DE     RecName: Full=89 kDa myeloperoxidase;
DE   Contains:
DE     RecName: Full=84 kDa myeloperoxidase;
DE   Contains:
DE     RecName: Full=Myeloperoxidase light chain;
DE   Contains:
DE     RecName: Full=Myeloperoxidase heavy chain;
DE   Flags: Precursor;
GN   Name=MPO;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IDA:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0050832; P:defense response to fungus; IEA:Ensembl.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0002149; P:hypochlorous acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0034374; P:low-density lipoprotein particle remodeling; IDA:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:BHF-UCL.
DR   GO; GO:0019430; P:removal of superoxide radicals; IEA:Ensembl.
DR   GO; GO:0002679; P:respiratory burst involved in defense response; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:UniProtKB.
DR   GO; GO:0001878; P:response to yeast; IEA:Ensembl.
//
ID   PERP_HUMAN              Reviewed;         193 AA.
AC   Q96FX8; B2RB73; E1P590; Q8IWS3; Q8N1J6; Q8NC16; Q9H1C5; Q9H230;
DE   RecName: Full=p53 apoptosis effector related to PMP-22;
DE   AltName: Full=Keratinocyte-associated protein 1;
DE            Short=KCP-1;
DE   AltName: Full=P53-induced protein PIGPC1;
DE   AltName: Full=Transmembrane protein THW;
GN   Name=PERP; Synonyms=KCP1, KRTCAP1, PIGPC1, THW;
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0097186; P:amelogenesis; IEA:Ensembl.
DR   GO; GO:0002934; P:desmosome organization; IEA:Ensembl.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
//
ID   PERPL_HUMAN             Reviewed;         196 AA.
AC   A6NN79;
DE   RecName: Full=Putative PERP-like protein;
//
ID   PERQ1_HUMAN             Reviewed;        1035 AA.
AC   O75420; Q6Y7W7; Q8WZ38;
DE   RecName: Full=PERQ amino acid-rich with GYF domain-containing protein 1;
DE   AltName: Full=GRB10-interacting GYF protein 1;
GN   Name=GIGYF1; Synonyms=CDS2, PERQ1; ORFNames=PP3360;
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
//
ID   PERQ2_HUMAN             Reviewed;        1299 AA.
AC   Q6Y7W6; A6H8W4; B9EG55; E9PBB0; O75137; Q7Z2Z8; Q7Z3I2; Q96HU4;
AC   Q9NV82;
DE   RecName: Full=PERQ amino acid-rich with GYF domain-containing protein 2;
DE   AltName: Full=GRB10-interacting GYF protein 2;
DE   AltName: Full=Trinucleotide repeat-containing gene 15 protein;
GN   Name=GIGYF2; Synonyms=KIAA0642, PERQ2, TNRC15;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0050881; P:musculoskeletal movement; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IMP:MGI.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
//
ID   PERT_HUMAN              Reviewed;         933 AA.
AC   P07202; P09934; P09935; Q8IUL0; Q8NF94; Q8NF95; Q8NF96; Q8NF97;
AC   Q8TCI9;
DE   RecName: Full=Thyroid peroxidase;
DE            Short=TPO;
DE            EC=1.11.1.8;
DE   Flags: Precursor;
GN   Name=TPO;
DR   GuidetoPHARMACOLOGY; 2526; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004447; F:iodide peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004601; F:peroxidase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IDA:DFLAT.
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; TAS:Reactome.
//
ID   PESC_HUMAN              Reviewed;         588 AA.
AC   O00541; Q6IC29;
DE   RecName: Full=Pescadillo homolog;
GN   Name=PES1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:UniProtKB.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:UniProtKB.
DR   GO; GO:0007000; P:nucleolus organization; IEA:Ensembl.
DR   GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IC:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IMP:MGI.
//
ID   PEX10_HUMAN             Reviewed;         326 AA.
AC   O60683; B3KWD8; Q5T095; Q9BW90;
DE   RecName: Full=Peroxisome biogenesis factor 10;
DE   AltName: Full=Peroxin-10;
DE   AltName: Full=Peroxisomal biogenesis factor 10;
DE   AltName: Full=Peroxisome assembly protein 10;
DE   AltName: Full=RING finger protein 69;
GN   Name=PEX10; Synonyms=RNF69;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007031; P:peroxisome organization; IDA:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IDA:UniProtKB.
//
ID   PEX12_HUMAN             Reviewed;         359 AA.
AC   O00623; B2R6M2;
DE   RecName: Full=Peroxisome assembly protein 12;
DE   AltName: Full=Peroxin-12;
DE   AltName: Full=Peroxisome assembly factor 3;
DE            Short=PAF-3;
GN   Name=PEX12; Synonyms=PAF3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IMP:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IMP:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; NAS:UniProtKB.
//
ID   PEX13_HUMAN             Reviewed;         403 AA.
AC   Q92968; B2RCS1;
DE   RecName: Full=Peroxisomal membrane protein PEX13;
DE   AltName: Full=Peroxin-13;
GN   Name=PEX13;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0060152; P:microtubule-based peroxisome localization; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; IMP:UniProtKB.
DR   GO; GO:0001967; P:suckling behavior; ISS:UniProtKB.
//
ID   PEX14_HUMAN             Reviewed;         377 AA.
AC   O75381; B2R7N1; B3KML6; B7Z1N2; Q8WX51;
DE   RecName: Full=Peroxisomal membrane protein PEX14;
DE   AltName: Full=PTS1 receptor-docking protein;
DE   AltName: Full=Peroxin-14;
DE   AltName: Full=Peroxisomal membrane anchor protein PEX14;
GN   Name=PEX14;
DR   GO; GO:0048487; F:beta-tubulin binding; IPI:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0034453; P:microtubule anchoring; IDA:UniProtKB.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:1901094; P:negative regulation of protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; ISS:UniProtKB.
DR   GO; GO:0036250; P:peroxisome transport along microtubule; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IMP:UniProtKB.
DR   GO; GO:0044721; P:protein import into peroxisome matrix, substrate release; IDA:UniProtKB.
DR   GO; GO:0016561; P:protein import into peroxisome matrix, translocation; IDA:UniProtKB.
//
ID   PEX16_HUMAN             Reviewed;         336 AA.
AC   Q9Y5Y5; Q9BWB9;
DE   RecName: Full=Peroxisomal membrane protein PEX16;
DE   AltName: Full=Peroxin-16;
DE   AltName: Full=Peroxisomal biogenesis factor 16;
GN   Name=PEX16;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032581; P:ER-dependent peroxisome organization; IDA:UniProtKB.
DR   GO; GO:0016557; P:peroxisome membrane biogenesis; IMP:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IMP:MGI.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IMP:UniProtKB.
DR   GO; GO:0070972; P:protein localization to endoplasmic reticulum; IDA:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; IMP:UniProtKB.
DR   GO; GO:0022615; P:protein to membrane docking; IDA:UniProtKB.
//
ID   PEX19_HUMAN             Reviewed;         299 AA.
AC   P40855; D3DVE7; Q5QNY4; Q8NI97;
DE   RecName: Full=Peroxisomal biogenesis factor 19;
DE   AltName: Full=33 kDa housekeeping protein;
DE   AltName: Full=Peroxin-19;
DE   AltName: Full=Peroxisomal farnesylated protein;
DE   Flags: Precursor;
GN   Name=PEX19; Synonyms=HK33, PXF; ORFNames=OK/SW-cl.22;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0036105; F:peroxisome membrane class-1 targeting sequence binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; IDA:UniProtKB.
DR   GO; GO:0072663; P:establishment of protein localization to peroxisome; IMP:UniProtKB.
DR   GO; GO:1900131; P:negative regulation of lipid binding; IDA:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IMP:UniProtKB.
DR   GO; GO:0016557; P:peroxisome membrane biogenesis; IDA:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   PEX1_HUMAN              Reviewed;        1283 AA.
AC   O43933; A4D1G3; A8KA90; Q96S71; Q96S72; Q96S73; Q99994;
DE   RecName: Full=Peroxisome biogenesis factor 1;
DE   AltName: Full=Peroxin-1;
DE   AltName: Full=Peroxisome biogenesis disorder protein 1;
GN   Name=PEX1;
DR   GO; GO:0005524; F:ATP binding; IMP:UniProtKB.
DR   GO; GO:0042623; F:ATPase activity, coupled; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:GOC.
DR   GO; GO:0060152; P:microtubule-based peroxisome localization; IMP:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IMP:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; IMP:UniProtKB.
//
ID   PEX26_HUMAN             Reviewed;         305 AA.
AC   Q7Z412; F6UBB5; Q7Z413; Q7Z414; Q7Z415; Q7Z416; Q96B12; Q9NWQ0;
AC   Q9NXU0;
DE   RecName: Full=Peroxisome assembly protein 26;
DE   AltName: Full=Peroxin-26;
GN   Name=PEX26;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IDA:UniProtKB.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IEA:InterPro.
//
ID   PEX2_HUMAN              Reviewed;         305 AA.
AC   P28328; Q567S6; Q9BW41;
DE   RecName: Full=Peroxisome biogenesis factor 2;
DE   AltName: Full=35 kDa peroxisomal membrane protein;
DE   AltName: Full=Peroxin-2;
DE   AltName: Full=Peroxisomal membrane protein 3;
DE   AltName: Full=Peroxisome assembly factor 1;
DE            Short=PAF-1;
DE   AltName: Full=RING finger protein 72;
GN   Name=PEX2; Synonyms=PAF1, PMP3, PMP35, PXMP3, RNF72;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IMP:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IMP:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IMP:UniProtKB.
DR   GO; GO:0045540; P:regulation of cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IMP:UniProtKB.
//
ID   PEX3_HUMAN              Reviewed;         373 AA.
AC   P56589; Q6FGP5;
DE   RecName: Full=Peroxisomal biogenesis factor 3;
DE   AltName: Full=Peroxin-3;
DE   AltName: Full=Peroxisomal assembly protein PEX3;
GN   Name=PEX3;
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0016557; P:peroxisome membrane biogenesis; IEA:Ensembl.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   PEX5R_HUMAN             Reviewed;         626 AA.
AC   Q8IYB4; B7Z2A5; B7Z305; B7Z318; B7Z5Z5; B7Z8P2; E7EUV8; E7EUZ0;
AC   E9PEC1; E9PH97; Q9NQD1; Q9P2U3; Q9P2U4;
DE   RecName: Full=PEX5-related protein;
DE   AltName: Full=PEX2-related protein;
DE   AltName: Full=PEX5-like protein;
DE   AltName: Full=Peroxin-5-related protein;
DE   AltName: Full=Peroxisome biogenesis factor 5-like;
DE   AltName: Full=Tetratricopeptide repeat-containing Rab8b-interacting protein;
DE            Short=Pex5Rp;
DE            Short=TRIP8b;
GN   Name=PEX5L; Synonyms=PEX5R, PXR2;
DR   GO; GO:0005052; F:peroxisome matrix targeting signal-1 binding; IBA:RefGenome.
DR   GO; GO:0000268; F:peroxisome targeting sequence binding; IDA:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; IPI:UniProtKB.
DR   GO; GO:0045185; P:maintenance of protein location; IEA:Ensembl.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IBA:RefGenome.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; IBA:RefGenome.
DR   GO; GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
//
ID   PEX5_HUMAN              Reviewed;         639 AA.
AC   P50542; A8K891; B4DZ45; B7ZAD5; D3DUT8; Q15115; Q15266; Q96FN7;
DE   RecName: Full=Peroxisomal targeting signal 1 receptor;
DE            Short=PTS1 receptor;
DE            Short=PTS1R;
DE   AltName: Full=PTS1-BP;
DE   AltName: Full=Peroxin-5;
DE   AltName: Full=Peroxisomal C-terminal targeting signal import receptor;
DE   AltName: Full=Peroxisome receptor 1;
GN   Name=PEX5; Synonyms=PXR1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005052; F:peroxisome matrix targeting signal-1 binding; IDA:UniProtKB.
DR   GO; GO:0000268; F:peroxisome targeting sequence binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; IPI:UniProtKB.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IEA:Ensembl.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:Ensembl.
DR   GO; GO:0007006; P:mitochondrial membrane organization; IEA:Ensembl.
DR   GO; GO:1901094; P:negative regulation of protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IGI:UniProtKB.
DR   GO; GO:0016560; P:protein import into peroxisome matrix, docking; IDA:UniProtKB.
DR   GO; GO:0016561; P:protein import into peroxisome matrix, translocation; IDA:UniProtKB.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IMP:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IEA:Ensembl.
//
ID   PEX6_HUMAN              Reviewed;         980 AA.
AC   Q13608; Q5T8W1; Q8WYQ2; Q99476;
DE   RecName: Full=Peroxisome assembly factor 2;
DE            Short=PAF-2;
DE   AltName: Full=Peroxin-6;
DE   AltName: Full=Peroxisomal biogenesis factor 6;
DE   AltName: Full=Peroxisomal-type ATPase 1;
GN   Name=PEX6; Synonyms=PXAAA1;
DR   GO; GO:0005524; F:ATP binding; IMP:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IMP:UniProtKB.
DR   GO; GO:0042623; F:ATPase activity, coupled; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:GOC.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0016561; P:protein import into peroxisome matrix, translocation; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; IMP:UniProtKB.
//
ID   PEX7_HUMAN              Reviewed;         323 AA.
AC   O00628;
DE   RecName: Full=Peroxisomal targeting signal 2 receptor;
DE            Short=PTS2 receptor;
DE   AltName: Full=Peroxin-7;
GN   Name=PEX7; Synonyms=PTS2R;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005053; F:peroxisome matrix targeting signal-2 binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0008611; P:ether lipid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0016558; P:protein import into peroxisome matrix; IMP:UniProtKB.
//
ID   PF21A_HUMAN             Reviewed;         680 AA.
AC   Q96BD5; D3DQP5; Q6AWA2; Q9C0G7; Q9H8V9; Q9HAK6; Q9NZE9;
DE   RecName: Full=PHD finger protein 21A;
DE   AltName: Full=BHC80a;
DE   AltName: Full=BRAF35-HDAC complex protein BHC80;
GN   Name=PHF21A; Synonyms=BHC80, KIAA1696; ORFNames=BM-006;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PF2R_HUMAN              Reviewed;         359 AA.
AC   P43088; A8K9Y0; Q2KHP3; Q6RYQ6; Q9P1X4;
DE   RecName: Full=Prostaglandin F2-alpha receptor;
DE            Short=PGF receptor;
DE            Short=PGF2-alpha receptor;
DE   AltName: Full=Prostanoid FP receptor;
GN   Name=PTGFR;
DR   GuidetoPHARMACOLOGY; 344; -.
DR   GO; GO:0004958; F:prostaglandin F receptor activity; IDA:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007567; P:parturition; TAS:ProtInc.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   PF21B_HUMAN             Reviewed;         531 AA.
AC   Q96EK2; B0QYW3; B0QYW4; B3KRU4; B7Z4F8; Q5TFL2; Q6ICC0;
DE   RecName: Full=PHD finger protein 21B;
GN   Name=PHF21B; Synonyms=KIAA1661;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PF4V_HUMAN              Reviewed;         104 AA.
AC   P10720; A1L4S0;
DE   RecName: Full=Platelet factor 4 variant;
DE   AltName: Full=C-X-C motif chemokine 4 variant;
DE   AltName: Full=CXCL4L1;
DE   AltName: Full=PF4alt;
DE   AltName: Full=PF4var1;
DE   Contains:
DE     RecName: Full=Platelet factor 4 variant(4-74);
DE   Contains:
DE     RecName: Full=Platelet factor 4 variant(5-74);
DE   Contains:
DE     RecName: Full=Platelet factor 4 variant(6-74);
DE   Flags: Precursor;
GN   Name=PF4V1; Synonyms=CXCL4V1, SCYB4V1;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0060326; P:cell chemotaxis; IEA:GOC.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   PFD1_HUMAN              Reviewed;         122 AA.
AC   O60925; B2RD02; Q53F95; Q96EX6;
DE   RecName: Full=Prefoldin subunit 1;
GN   Name=PFDN1; Synonyms=PFD1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0042113; P:B cell activation; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
//
ID   PFD2_HUMAN              Reviewed;         154 AA.
AC   Q9UHV9; Q9P0P7; Q9UN05;
DE   RecName: Full=Prefoldin subunit 2;
GN   Name=PFDN2; Synonyms=PFD2; ORFNames=HSPC231;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   PFD3_HUMAN              Reviewed;         197 AA.
AC   P61758; B2R8L5; O55228; Q15765; Q5JT81; Q86X96;
DE   RecName: Full=Prefoldin subunit 3;
DE   AltName: Full=HIBBJ46;
DE   AltName: Full=Von Hippel-Lindau-binding protein 1;
DE            Short=VBP-1;
DE            Short=VHL-binding protein 1;
GN   Name=VBP1; Synonyms=PFDN3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
//
ID   PFD4_HUMAN              Reviewed;         134 AA.
AC   Q9NQP4; Q5TD11; Q92779;
DE   RecName: Full=Prefoldin subunit 4;
DE   AltName: Full=Protein C-1;
GN   Name=PFDN4; Synonyms=PFD4;
DR   GO; GO:0051087; F:chaperone binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
//
ID   PFD5_HUMAN              Reviewed;         154 AA.
AC   Q99471; A8K9A8; Q54AA8; Q9C083; Q9C084;
DE   RecName: Full=Prefoldin subunit 5;
DE   AltName: Full=C-Myc-binding protein Mm-1;
DE   AltName: Full=Myc modulator 1;
GN   Name=PFDN5; Synonyms=MM1, PFD5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
//
ID   PFD6_HUMAN              Reviewed;         129 AA.
AC   O15212;
DE   RecName: Full=Prefoldin subunit 6;
DE   AltName: Full=Protein Ke2;
GN   Name=PFDN6; Synonyms=HKE2, PFD6;
DR   GO; GO:0051087; F:chaperone binding; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   PG12A_HUMAN             Reviewed;         189 AA.
AC   Q9BZM1; Q9BZ89;
DE   RecName: Full=Group XIIA secretory phospholipase A2;
DE            Short=GXII sPLA2;
DE            Short=sPLA2-XII;
DE            EC=3.1.1.4;
DE   AltName: Full=Phosphatidylcholine 2-acylhydrolase 12A;
DE   Flags: Precursor;
GN   Name=PLA2G12A; Synonyms=PLA2G12; ORFNames=FKSG38, UNQ2519/PRO6012;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0047498; F:calcium-dependent phospholipase A2 activity; NAS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036148; P:phosphatidylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PG12B_HUMAN             Reviewed;         195 AA.
AC   Q9BX93; B7ZL23; Q52LB2; Q96Q99;
DE   RecName: Full=Group XIIB secretory phospholipase A2-like protein;
DE   AltName: Full=Group XIII secretory phospholipase A2-like protein;
DE            Short=GXIII sPLA2-like;
DE   AltName: Full=sPLA2-GXIIB;
DE            Short=GXIIB;
DE   Flags: Precursor;
GN   Name=PLA2G12B; Synonyms=PLA2G13; ORFNames=FKSG71;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
//
ID   PG2IP_HUMAN             Reviewed;         699 AA.
AC   Q9H720; B2RPD7;
DE   RecName: Full=PGAP2-interacting protein;
DE   AltName: Full=Cell wall biogenesis protein 43 C-terminal homolog;
GN   Name=CWH43; Synonyms=PGAP2IP;
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-KW.
//
ID   PGAM1_HUMAN             Reviewed;         254 AA.
AC   P18669; Q9BWC0;
DE   RecName: Full=Phosphoglycerate mutase 1;
DE            EC=3.1.3.13;
DE            EC=5.4.2.11;
DE            EC=5.4.2.4;
DE   AltName: Full=BPG-dependent PGAM 1;
DE   AltName: Full=Phosphoglycerate mutase isozyme B;
DE            Short=PGAM-B;
GN   Name=PGAM1; Synonyms=PGAMA; ORFNames=CDABP0006;
DR   GO; GO:0004083; F:bisphosphoglycerate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004082; F:bisphosphoglycerate mutase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004619; F:phosphoglycerate mutase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IDA:UniProt.
DR   GO; GO:0006110; P:regulation of glycolytic process; IDA:UniProtKB.
DR   GO; GO:0043456; P:regulation of pentose-phosphate shunt; IDA:UniProtKB.
DR   GO; GO:0045730; P:respiratory burst; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGAM2_HUMAN             Reviewed;         253 AA.
AC   P15259;
DE   RecName: Full=Phosphoglycerate mutase 2;
DE            EC=3.1.3.13;
DE            EC=5.4.2.11;
DE            EC=5.4.2.4;
DE   AltName: Full=BPG-dependent PGAM 2;
DE   AltName: Full=Muscle-specific phosphoglycerate mutase;
DE   AltName: Full=Phosphoglycerate mutase isozyme M;
DE            Short=PGAM-M;
GN   Name=PGAM2; Synonyms=PGAMM;
DR   GO; GO:0046538; F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; IEA:Ensembl.
DR   GO; GO:0004083; F:bisphosphoglycerate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004082; F:bisphosphoglycerate mutase activity; IEA:UniProtKB-EC.
DR   GO; GO:0048037; F:cofactor binding; IEA:Ensembl.
DR   GO; GO:0004619; F:phosphoglycerate mutase activity; IMP:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; IMP:UniProtKB.
DR   GO; GO:0046689; P:response to mercury ion; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006941; P:striated muscle contraction; IMP:UniProtKB.
//
ID   PGAM4_HUMAN             Reviewed;         254 AA.
AC   Q8N0Y7; Q5JPN2; Q8NI24; Q8NI25; Q8NI26;
DE   RecName: Full=Probable phosphoglycerate mutase 4;
DE            EC=3.1.3.13;
DE            EC=5.4.2.11;
DE            EC=5.4.2.4;
GN   Name=PGAM4; Synonyms=PGAM3;
DR   GO; GO:0004083; F:bisphosphoglycerate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004082; F:bisphosphoglycerate mutase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004619; F:phosphoglycerate mutase activity; NAS:UniProtKB.
DR   GO; GO:0006096; P:glycolytic process; NAS:UniProtKB.
DR   GO; GO:1902093; P:positive regulation of sperm motility; NAS:UniProt.
//
ID   PGAM5_HUMAN             Reviewed;         289 AA.
AC   Q96HS1; A9LN06; C9IZY7; Q96JB0;
DE   RecName: Full=Serine/threonine-protein phosphatase PGAM5, mitochondrial;
DE            EC=3.1.3.16;
DE   AltName: Full=Bcl-XL-binding protein v68;
DE   AltName: Full=Phosphoglycerate mutase family member 5;
GN   Name=PGAM5;
DR   GO; GO:0005096; F:GTPase activator activity; IMP:UniProtKB.
DR   GO; GO:0016791; F:phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IMP:GOC.
DR   GO; GO:0070266; P:necroptotic process; IMP:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IMP:GOC.
//
ID   PGAP1_HUMAN             Reviewed;         922 AA.
AC   Q75T13; Q4G0R8; Q4ZG47; Q53SM0; Q6AW92; Q6UWV4; Q9HA24;
DE   RecName: Full=GPI inositol-deacylase;
DE            EC=3.1.-.-;
DE   AltName: Full=Post-GPI attachment to proteins factor 1;
DE            Short=hPGAP1;
GN   Name=PGAP1; ORFNames=UNQ3024/PRO9822;
DR   GO; GO:0004518; F:nuclease activity; ISS:UniProtKB.
DR   GO; GO:0042578; F:phosphoric ester hydrolase activity; ISS:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; TAS:Reactome.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0021871; P:forebrain regionalization; IEA:Ensembl.
DR   GO; GO:0060322; P:head development; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0015798; P:myo-inositol transport; ISS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   PGAP2_HUMAN             Reviewed;         254 AA.
AC   Q9UHJ9; E9PJG5; H7BXL9; Q6UC77; Q96G66; Q9UF01; Q9Y4N1;
DE   RecName: Full=Post-GPI attachment to proteins factor 2;
DE   AltName: Full=FGF receptor-activating protein 1;
GN   Name=PGAP2; Synonyms=FRAG1;
DR   GO; GO:0008565; F:protein transporter activity; ISS:UniProtKB.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IEA:Ensembl.
//
ID   PGAP3_HUMAN             Reviewed;         320 AA.
AC   Q96FM1; Q86Z03; Q8NBJ8;
DE   RecName: Full=Post-GPI attachment to proteins factor 3;
DE   AltName: Full=COS16 homolog;
DE            Short=hCOS16;
DE   AltName: Full=Gene coamplified with ERBB2 protein;
DE   AltName: Full=PER1-like domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=PGAP3; Synonyms=CAB2, PERLD1; ORFNames=UNQ546/PRO1100;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IMP:UniProtKB.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006505; P:GPI anchor metabolic process; IMP:UniProtKB.
//
ID   PGBD2_HUMAN             Reviewed;         592 AA.
AC   Q6P3X8; B3KVR8; Q6MZF8;
DE   RecName: Full=PiggyBac transposable element-derived protein 2;
GN   Name=PGBD2;
//
ID   PGBD3_HUMAN             Reviewed;         593 AA.
AC   Q8N328; B3KQC4; Q5W0M0; Q6PIH0;
DE   RecName: Full=PiggyBac transposable element-derived protein 3;
GN   Name=PGBD3;
//
ID   PGBD4_HUMAN             Reviewed;         585 AA.
AC   Q96DM1; A1L487; A8K0C6; Q8N9E8;
DE   RecName: Full=PiggyBac transposable element-derived protein 4;
GN   Name=PGBD4;
//
ID   PGBD1_HUMAN             Reviewed;         809 AA.
AC   Q96JS3; Q53F43; Q6NTF5; Q8WWS4;
DE   RecName: Full=PiggyBac transposable element-derived protein 1;
DE   AltName: Full=Cerebral protein 4;
GN   Name=PGBD1; ORFNames=hucep-4;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   PGBM_HUMAN              Reviewed;        4391 AA.
AC   P98160; Q16287; Q5SZI3; Q9H3V5;
DE   RecName: Full=Basement membrane-specific heparan sulfate proteoglycan core protein;
DE            Short=HSPG;
DE   AltName: Full=Perlecan;
DE            Short=PLC;
DE   Contains:
DE     RecName: Full=Endorepellin;
DE   Contains:
DE     RecName: Full=LG3 peptide;
DE   Flags: Precursor;
GN   Name=HSPG2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGBD5_HUMAN             Reviewed;         455 AA.
AC   Q8N414; A0PJF3; B9EK58; Q5SR37; Q6PJN2;
DE   RecName: Full=PiggyBac transposable element-derived protein 5;
GN   Name=PGBD5;
//
ID   PGCA_HUMAN              Reviewed;        2415 AA.
AC   P16112; Q13650; Q9UCD3; Q9UCP4; Q9UCP5; Q9UDE0;
DE   RecName: Full=Aggrecan core protein;
DE   AltName: Full=Cartilage-specific proteoglycan core protein;
DE            Short=CSPCP;
DE   AltName: Full=Chondroitin sulfate proteoglycan core protein 1;
DE            Short=Chondroitin sulfate proteoglycan 1;
DE   Contains:
DE     RecName: Full=Aggrecan core protein 2;
DE   Flags: Precursor;
GN   Name=ACAN; Synonyms=AGC1, CSPG1, MSK16;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:UniProtKB.
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGCB_HUMAN              Reviewed;         911 AA.
AC   Q96GW7; D3DVC2; Q5SZ10; Q5T3I5; Q8TBB9; Q9HBK1; Q9HBK4;
DE   RecName: Full=Brevican core protein;
DE   AltName: Full=Brain-enriched hyaluronan-binding protein;
DE            Short=BEHAB;
DE   AltName: Full=Chondroitin sulfate proteoglycan 7;
DE   Flags: Precursor;
GN   Name=BCAN; Synonyms=BEHAB, CSPG7; ORFNames=UNQ2525/PRO6018;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGDH_HUMAN              Reviewed;         266 AA.
AC   P15428; B4DTA4; B4DU74; B4DV57; D3DP43; E7EV11; O00749; Q06F08;
AC   Q12998;
DE   RecName: Full=15-hydroxyprostaglandin dehydrogenase [NAD(+)];
DE            Short=15-PGDH;
DE            EC=1.1.1.141;
DE   AltName: Full=Prostaglandin dehydrogenase 1;
GN   Name=HPGD; Synonyms=PGDH1;
DR   GO; GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IDA:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IDA:UniProtKB.
DR   GO; GO:0070403; F:NAD+ binding; IDA:UniProtKB.
DR   GO; GO:0004957; F:prostaglandin E receptor activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IDA:UniProtKB.
DR   GO; GO:2001300; P:lipoxin metabolic process; TAS:Reactome.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0030728; P:ovulation; ISS:UniProtKB.
DR   GO; GO:0007567; P:parturition; IDA:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
//
ID   PGES2_HUMAN             Reviewed;         377 AA.
AC   Q9H7Z7; Q53EW9; Q5SYV6; Q96GI0; Q96GL2;
DE   RecName: Full=Prostaglandin E synthase 2;
DE            EC=4.1.2.-;
DE            EC=5.3.99.3;
DE   AltName: Full=Microsomal prostaglandin E synthase 2;
DE            Short=mPGES-2;
DE   Contains:
DE     RecName: Full=Prostaglandin E synthase 2 truncated form;
GN   Name=PTGES2; Synonyms=C9orf15, PGES2;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0043295; F:glutathione binding; ISS:UniProtKB.
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0016829; F:lyase activity; ISS:UniProtKB.
DR   GO; GO:0050220; F:prostaglandin-E synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046903; P:secretion; IEA:Ensembl.
//
ID   PGFRA_HUMAN             Reviewed;        1089 AA.
AC   P16234; B2RE69; E9PBH0; Q6P4H5; Q96KZ7; Q9UD28;
DE   RecName: Full=Platelet-derived growth factor receptor alpha;
DE            Short=PDGF-R-alpha;
DE            Short=PDGFR-alpha;
DE            EC=2.7.10.1;
DE   AltName: Full=Alpha platelet-derived growth factor receptor;
DE   AltName: Full=Alpha-type platelet-derived growth factor receptor;
DE   AltName: Full=CD140 antigen-like family member A;
DE   AltName: Full=CD140a antigen;
DE   AltName: Full=Platelet-derived growth factor alpha receptor;
DE   AltName: Full=Platelet-derived growth factor receptor 2;
DE            Short=PDGFR-2;
DE   AltName: CD_antigen=CD140a;
DE   Flags: Precursor;
GN   Name=PDGFRA; Synonyms=PDGFR2, RHEPDGFRA;
DR   GuidetoPHARMACOLOGY; 1803; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005018; F:platelet-derived growth factor alpha-receptor activity; IDA:UniProtKB.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:UniProtKB.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0038085; F:vascular endothelial growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.
DR   GO; GO:0001775; P:cell activation; TAS:BHF-UCL.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008210; P:estrogen metabolic process; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0001553; P:luteinization; ISS:UniProtKB.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.
DR   GO; GO:0010544; P:negative regulation of platelet activation; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; IMP:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035790; P:platelet-derived growth factor receptor-alpha signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IMP:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; TAS:UniProtKB.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.
DR   GO; GO:0050920; P:regulation of chemotaxis; IMP:UniProtKB.
DR   GO; GO:2000739; P:regulation of mesenchymal stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
//
ID   PGFRB_HUMAN             Reviewed;        1106 AA.
AC   P09619; Q8N5L4;
DE   RecName: Full=Platelet-derived growth factor receptor beta;
DE            Short=PDGF-R-beta;
DE            Short=PDGFR-beta;
DE            EC=2.7.10.1;
DE   AltName: Full=Beta platelet-derived growth factor receptor;
DE   AltName: Full=Beta-type platelet-derived growth factor receptor;
DE   AltName: Full=CD140 antigen-like family member B;
DE   AltName: Full=Platelet-derived growth factor receptor 1;
DE            Short=PDGFR-1;
DE   AltName: CD_antigen=CD140b;
DE   Flags: Precursor;
GN   Name=PDGFRB; Synonyms=PDGFR, PDGFR1;
DR   GuidetoPHARMACOLOGY; 1804; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004992; F:platelet activating factor receptor activity; TAS:ProtInc.
DR   GO; GO:0005019; F:platelet-derived growth factor beta-receptor activity; IDA:UniProtKB.
DR   GO; GO:0048407; F:platelet-derived growth factor binding; IDA:UniProtKB.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005017; F:platelet-derived growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0038085; F:vascular endothelial growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0035909; P:aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0055003; P:cardiac myofibril assembly; ISS:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0060981; P:cell migration involved in coronary angiogenesis; ISS:UniProtKB.
DR   GO; GO:0035441; P:cell migration involved in vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0036120; P:cellular response to platelet-derived growth factor stimulus; TAS:GOC.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GOC.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0072278; P:metanephric comma-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.
DR   GO; GO:0072262; P:metanephric glomerular mesangial cell proliferation involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0035789; P:metanephric mesenchymal cell migration; IEA:Ensembl.
DR   GO; GO:0072075; P:metanephric mesenchyme development; IEA:Ensembl.
DR   GO; GO:0072284; P:metanephric S-shaped body morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; IMP:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IMP:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035791; P:platelet-derived growth factor receptor-beta signaling pathway; IMP:UniProtKB.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; ISS:UniProtKB.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0035793; P:positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; ISS:UniProtKB.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; ISS:BHF-UCL.
DR   GO; GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0034405; P:response to fluid shear stress; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0061298; P:retina vasculature development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0071670; P:smooth muscle cell chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   PGFS_HUMAN              Reviewed;         198 AA.
AC   Q8TBF2; A8K793; B3KPY3; B4DQR9; B4E0S5; B7ZAC8; B9DI90; B9DI92;
AC   J3KQD0; Q8N2H0;
DE   RecName: Full=Prostamide/prostaglandin F synthase;
DE            Short=Prostamide/PG F synthase;
DE            Short=Prostamide/PGF synthase;
DE            EC=1.11.1.20;
DE   AltName: Full=Protein FAM213B;
GN   Name=FAM213B; Synonyms=C1orf93;
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; ISS:UniProtKB.
DR   GO; GO:0047017; F:prostaglandin-F synthase activity; ISS:UniProt.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGFRL_HUMAN             Reviewed;         375 AA.
AC   Q15198; A8K085; Q6FH04;
DE   RecName: Full=Platelet-derived growth factor receptor-like protein;
DE            Short=PDGFR-like protein;
DE   AltName: Full=PDGF receptor beta-like tumor suppressor;
DE   Flags: Precursor;
GN   Name=PDGFRL; Synonyms=PRLTS;
DR   GO; GO:0004992; F:platelet activating factor receptor activity; TAS:ProtInc.
DR   GO; GO:0005019; F:platelet-derived growth factor beta-receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GOC.
DR   GO; GO:0035791; P:platelet-derived growth factor receptor-beta signaling pathway; TAS:GOC.
//
ID   PGH1_HUMAN              Reviewed;         599 AA.
AC   P23219; A8K1V7; B4DHQ2; B4E2S5; Q15122; Q3HY28; Q3HY29; Q5T7T6;
AC   Q5T7T7; Q5T7T8;
DE   RecName: Full=Prostaglandin G/H synthase 1;
DE            EC=1.14.99.1;
DE   AltName: Full=Cyclooxygenase-1;
DE            Short=COX-1;
DE   AltName: Full=Prostaglandin H2 synthase 1;
DE            Short=PGH synthase 1;
DE            Short=PGHS-1;
DE            Short=PHS 1;
DE   AltName: Full=Prostaglandin-endoperoxide synthase 1;
DE   Flags: Precursor;
GN   Name=PTGS1; Synonyms=COX1;
DR   GuidetoPHARMACOLOGY; 1375; -.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0004666; F:prostaglandin-endoperoxide synthase activity; IDA:BHF-UCL.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; IDA:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   PGH2_HUMAN              Reviewed;         604 AA.
AC   P35354; A8K802; Q16876;
DE   RecName: Full=Prostaglandin G/H synthase 2;
DE            EC=1.14.99.1;
DE   AltName: Full=Cyclooxygenase-2;
DE            Short=COX-2;
DE   AltName: Full=PHS II;
DE   AltName: Full=Prostaglandin H2 synthase 2;
DE            Short=PGH synthase 2;
DE            Short=PGHS-2;
DE   AltName: Full=Prostaglandin-endoperoxide synthase 2;
DE   Flags: Precursor;
GN   Name=PTGS2; Synonyms=COX2;
DR   GuidetoPHARMACOLOGY; 1376; -.
DR   GO; GO:0050473; F:arachidonate 15-lipoxygenase activity; TAS:Reactome.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; NAS:UniProtKB.
DR   GO; GO:0004666; F:prostaglandin-endoperoxide synthase activity; IDA:UniProtKB.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0071318; P:cellular response to ATP; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0019371; P:cyclooxygenase pathway; IDA:BHF-UCL.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0019372; P:lipoxygenase pathway; TAS:Reactome.
DR   GO; GO:0035633; P:maintenance of blood-brain barrier; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045986; P:negative regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0032227; P:negative regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0030728; P:ovulation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0090336; P:positive regulation of brown fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0031622; P:positive regulation of fever generation; ISS:BHF-UCL.
DR   GO; GO:0090271; P:positive regulation of fibroblast growth factor production; ISS:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0090362; P:positive regulation of platelet-derived growth factor production; ISS:BHF-UCL.
DR   GO; GO:0031394; P:positive regulation of prostaglandin biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0031915; P:positive regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0071636; P:positive regulation of transforming growth factor beta production; ISS:BHF-UCL.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:BHF-UCL.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; TAS:ProtInc.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; NAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0009750; P:response to fructose; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010226; P:response to lithium ion; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGK1_HUMAN              Reviewed;         417 AA.
AC   P00558; A8K4W6; Q5J7W1; Q6IBT6; Q8NI87;
DE   RecName: Full=Phosphoglycerate kinase 1;
DE            EC=2.7.2.3;
DE   AltName: Full=Cell migration-inducing gene 10 protein;
DE   AltName: Full=Primer recognition protein 2;
DE            Short=PRP 2;
GN   Name=PGK1; Synonyms=PGKA; ORFNames=MIG10, OK/SW-cl.110;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0004618; F:phosphoglycerate kinase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0016310; P:phosphorylation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGK2_HUMAN              Reviewed;         417 AA.
AC   P07205; B2R6Y8; Q9H107;
DE   RecName: Full=Phosphoglycerate kinase 2;
DE            EC=2.7.2.3;
DE   AltName: Full=Phosphoglycerate kinase, testis specific;
GN   Name=PGK2; Synonyms=PGKB;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0004618; F:phosphoglycerate kinase activity; ISS:UniProtKB.
DR   GO; GO:0006096; P:glycolytic process; NAS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; ISS:UniProtKB.
//
ID   PGLT1_HUMAN             Reviewed;         392 AA.
AC   Q8NBL1; B2RD13; Q53GJ4; Q8N2T1;
DE   RecName: Full=Protein O-glucosyltransferase 1;
DE            EC=2.4.1.-;
DE   AltName: Full=CAP10-like 46 kDa protein;
DE            Short=hCLP46;
DE   AltName: Full=KTEL motif-containing protein 1;
DE   AltName: Full=Myelodysplastic syndromes relative protein;
DE   AltName: Full=O-glucosyltransferase Rumi homolog;
DE            Short=hRumi;
DE   AltName: Full=Protein O-xylosyltransferase;
DE            EC=2.4.2.26;
DE   Flags: Precursor;
GN   Name=POGLUT1; Synonyms=C3orf9, CLP46, KTELC1, MDSRP;
GN   ORFNames=MDS010, UNQ490/PRO1006;
DR   GO; GO:0046527; F:glucosyltransferase activity; IDA:MGI.
DR   GO; GO:0035251; F:UDP-glucosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0035252; F:UDP-xylosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0072358; P:cardiovascular system development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:MGI.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; IEA:Ensembl.
//
ID   PGM1_HUMAN              Reviewed;         562 AA.
AC   P36871; B2R5N9; B4DPV0; Q16105; Q16106; Q5BKZ9; Q6NW22; Q86U74;
AC   Q96J40; Q9NTY4;
DE   RecName: Full=Phosphoglucomutase-1;
DE            Short=PGM 1;
DE            EC=5.4.2.2;
DE   AltName: Full=Glucose phosphomutase 1;
GN   Name=PGM1;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004614; F:phosphoglucomutase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019388; P:galactose catabolic process; IBA:RefGenome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; NAS:UniProtKB.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IBA:RefGenome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0006096; P:glycolytic process; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGM2L_HUMAN             Reviewed;         622 AA.
AC   Q6PCE3; Q96MQ7; Q9UIK3;
DE   RecName: Full=Glucose 1,6-bisphosphate synthase;
DE            EC=2.7.1.106;
DE   AltName: Full=PMMLP;
DE   AltName: Full=Phosphoglucomutase-2-like 1;
GN   Name=PGM2L1; Synonyms=BM32A;
DR   GO; GO:0047933; F:glucose-1,6-bisphosphate synthase activity; IDA:UniProtKB.
DR   GO; GO:0004614; F:phosphoglucomutase activity; IBA:RefGenome.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IBA:RefGenome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IDA:GOC.
//
ID   PGM2_HUMAN              Reviewed;         612 AA.
AC   Q96G03; Q53FP5; Q5QTR0; Q9H0P9; Q9NV22;
DE   RecName: Full=Phosphoglucomutase-2;
DE            Short=PGM 2;
DE            EC=5.4.2.2;
DE   AltName: Full=Glucose phosphomutase 2;
DE   AltName: Full=Phosphodeoxyribomutase;
DE   AltName: Full=Phosphopentomutase;
DE            EC=5.4.2.7;
GN   Name=PGM2; ORFNames=MSTP006;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004614; F:phosphoglucomutase activity; IBA:RefGenome.
DR   GO; GO:0008973; F:phosphopentomutase activity; IDA:UniProtKB.
DR   GO; GO:0016052; P:carbohydrate catabolic process; IBA:RefGenome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0046386; P:deoxyribose phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019388; P:galactose catabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGM5_HUMAN              Reviewed;         567 AA.
AC   Q15124; B1AM46; B4DLQ6; Q5VYV3; Q8N527; Q9UDH4;
DE   RecName: Full=Phosphoglucomutase-like protein 5;
DE   AltName: Full=Aciculin;
DE   AltName: Full=Phosphoglucomutase-related protein;
DE            Short=PGM-RP;
GN   Name=PGM5; Synonyms=PGMRP;
DR   GO; GO:0016868; F:intramolecular transferase activity, phosphotransferases; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
//
ID   PGPI_HUMAN              Reviewed;         209 AA.
AC   Q9NXJ5; A8K1Q3;
DE   RecName: Full=Pyroglutamyl-peptidase 1;
DE            EC=3.4.19.3;
DE   AltName: Full=5-oxoprolyl-peptidase;
DE   AltName: Full=Pyroglutamyl aminopeptidase I;
DE            Short=PAP-I;
DE   AltName: Full=Pyroglutamyl-peptidase I;
DE            Short=PGP-I;
DE   AltName: Full=Pyrrolidone-carboxylate peptidase;
GN   Name=PGPEP1; Synonyms=PGPI;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
//
ID   PGPIL_HUMAN             Reviewed;         196 AA.
AC   A6NFU8; H0YF86;
DE   RecName: Full=Pyroglutamyl-peptidase 1-like protein;
DE            EC=3.4.19.-;
GN   Name=PGPEP1L;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
//
ID   PGPS1_HUMAN             Reviewed;         556 AA.
AC   Q32NB8; B7ZA32; Q8IYK9; Q8TA85; Q96A75; Q9H7G9; Q9NPW7;
DE   RecName: Full=CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial;
DE            EC=2.7.8.5;
DE   AltName: Full=Phosphatidylglycerophosphate synthase 1;
DE            Short=PGP synthase 1;
DE   Flags: Precursor;
GN   Name=PGS1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; ISS:BHF-UCL.
DR   GO; GO:0008444; F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity; ISS:BHF-UCL.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0046339; P:diacylglycerol metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGP_HUMAN               Reviewed;         321 AA.
AC   A6NDG6;
DE   RecName: Full=Phosphoglycolate phosphatase;
DE            Short=PGP;
DE            Short=PGPase;
DE            EC=3.1.3.18;
DE            EC=3.1.3.48;
GN   Name=PGP;
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0098519; F:nucleotide phosphatase activity, acting on free nucleotides; ISS:UniProtKB.
DR   GO; GO:0008967; F:phosphoglycolate phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0016311; P:dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; ISS:UniProtKB.
//
ID   PGRC1_HUMAN             Reviewed;         195 AA.
AC   O00264; B7Z1L3; Q9UGJ9;
DE   RecName: Full=Membrane-associated progesterone receptor component 1;
DE            Short=mPR;
GN   Name=PGRMC1; Synonyms=HPR6.6, PGRMC;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005496; F:steroid binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
//
ID   PGRC2_HUMAN             Reviewed;         223 AA.
AC   O15173; Q569H1;
DE   RecName: Full=Membrane-associated progesterone receptor component 2;
DE   AltName: Full=Progesterone membrane-binding protein;
DE   AltName: Full=Steroid receptor protein DG6;
GN   Name=PGRMC2; Synonyms=DG6, PMBP;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005496; F:steroid binding; TAS:ProtInc.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0043401; P:steroid hormone mediated signaling pathway; TAS:GOC.
//
ID   PGRP1_HUMAN             Reviewed;         196 AA.
AC   O75594; Q4VB36;
DE   RecName: Full=Peptidoglycan recognition protein 1;
DE   AltName: Full=Peptidoglycan recognition protein short;
DE            Short=PGRP-S;
DE   Flags: Precursor;
GN   Name=PGLYRP1; Synonyms=PGLYRP, PGRP, TNFSF3L;
GN   ORFNames=SBBI68, UNQ639/PRO1269;
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR   GO; GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.
DR   GO; GO:0016019; F:peptidoglycan receptor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
DR   GO; GO:0016045; P:detection of bacterium; IDA:UniProtKB.
DR   GO; GO:0044117; P:growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032827; P:negative regulation of natural killer cell differentiation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; IDA:GOC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
//
ID   PGRP2_HUMAN             Reviewed;         576 AA.
AC   Q96PD5; A8K8C7; B2RMZ2; Q68CK1; Q96N74; Q9UC60;
DE   RecName: Full=N-acetylmuramoyl-L-alanine amidase;
DE            EC=3.5.1.28;
DE   AltName: Full=Peptidoglycan recognition protein 2;
DE   AltName: Full=Peptidoglycan recognition protein long;
DE            Short=PGRP-L;
DE   Flags: Precursor;
GN   Name=PGLYRP2; Synonyms=PGLYRPL, PGRPL; ORFNames=UNQ3103/PRO10102;
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; TAS:UniProtKB.
DR   GO; GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.
DR   GO; GO:0016019; F:peptidoglycan receptor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
DR   GO; GO:0016045; P:detection of bacterium; IDA:UniProtKB.
DR   GO; GO:0044117; P:growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032827; P:negative regulation of natural killer cell differentiation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; IDA:GOC.
DR   GO; GO:0001519; P:peptide amidation; NAS:UniProtKB.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
//
ID   PGRP3_HUMAN             Reviewed;         341 AA.
AC   Q96LB9; A1A4U8; Q5SY65;
DE   RecName: Full=Peptidoglycan recognition protein 3;
DE   AltName: Full=Peptidoglycan recognition protein I-alpha;
DE            Short=PGLYRPIalpha;
DE            Short=PGRP-I-alpha;
DE   AltName: Full=Peptidoglycan recognition protein intermediate alpha;
DE   Flags: Precursor;
GN   Name=PGLYRP3; Synonyms=PGRPIA;
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR   GO; GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.
DR   GO; GO:0016019; F:peptidoglycan receptor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
DR   GO; GO:0016045; P:detection of bacterium; IDA:UniProtKB.
DR   GO; GO:0044117; P:growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032827; P:negative regulation of natural killer cell differentiation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; IDA:GOC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
//
ID   PGRP4_HUMAN             Reviewed;         373 AA.
AC   Q96LB8; A8K838; Q3B822; Q3B823; Q5SY63; Q5SY64; Q9HD75;
DE   RecName: Full=Peptidoglycan recognition protein 4;
DE   AltName: Full=Peptidoglycan recognition protein I-beta;
DE            Short=PGLYRPIbeta;
DE            Short=PGRP-I-beta;
DE   AltName: Full=Peptidoglycan recognition protein intermediate beta;
DE   Flags: Precursor;
GN   Name=PGLYRP4; Synonyms=PGRPIB; ORFNames=SBBI67;
DR   GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR   GO; GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.
DR   GO; GO:0016019; F:peptidoglycan receptor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
DR   GO; GO:0016045; P:detection of bacterium; IDA:UniProtKB.
DR   GO; GO:0044117; P:growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032827; P:negative regulation of natural killer cell differentiation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; IDA:GOC.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
//
ID   PGS1_HUMAN              Reviewed;         368 AA.
AC   P21810; D3DWU3; P13247;
DE   RecName: Full=Biglycan;
DE   AltName: Full=Bone/cartilage proteoglycan I;
DE   AltName: Full=PG-S1;
DE   Flags: Precursor;
GN   Name=BGN; Synonyms=SLRR1A;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PGS2_HUMAN              Reviewed;         359 AA.
AC   P07585; Q9P0Z0; Q9P0Z1; Q9Y5N8; Q9Y5N9;
DE   RecName: Full=Decorin;
DE   AltName: Full=Bone proteoglycan II;
DE   AltName: Full=PG-S2;
DE   AltName: Full=PG40;
DE   Flags: Precursor;
GN   Name=DCN; Synonyms=SLRR1B;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030207; P:chondroitin sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   PGSF1_HUMAN             Reviewed;         128 AA.
AC   Q8N6C7; D6W630; Q17RJ9; Q8N6C6;
DE   RecName: Full=Putative uncharacterized protein encoded by MIR7-3HG;
DE   AltName: Full=Pituitary gland-specific factor 1;
GN   Name=MIR7-3HG; Synonyms=C19orf30, LINC00306, NCRNA00306, PGSF1;
//
ID   PGTA_HUMAN              Reviewed;         567 AA.
AC   Q92696; A8K5N2; D3DS69;
DE   RecName: Full=Geranylgeranyl transferase type-2 subunit alpha;
DE            EC=2.5.1.60;
DE   AltName: Full=Geranylgeranyl transferase type II subunit alpha;
DE   AltName: Full=Rab geranyl-geranyltransferase subunit alpha;
DE            Short=Rab GG transferase alpha;
DE            Short=Rab GGTase alpha;
DE   AltName: Full=Rab geranylgeranyltransferase subunit alpha;
GN   Name=RABGGTA;
DR   GO; GO:0004663; F:Rab geranylgeranyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0018344; P:protein geranylgeranylation; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PGTB1_HUMAN             Reviewed;         377 AA.
AC   P53609; Q5MJP9;
DE   RecName: Full=Geranylgeranyl transferase type-1 subunit beta;
DE            EC=2.5.1.59;
DE   AltName: Full=Geranylgeranyl transferase type I subunit beta;
DE            Short=GGTase-I-beta;
DE   AltName: Full=Type I protein geranyl-geranyltransferase subunit beta;
GN   Name=PGGT1B;
DR   GO; GO:0004662; F:CAAX-protein geranylgeranyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0004661; F:protein geranylgeranyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0051771; P:negative regulation of nitric-oxide synthase biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0018344; P:protein geranylgeranylation; IDA:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
//
ID   PGTB2_HUMAN             Reviewed;         331 AA.
AC   P53611; Q92697;
DE   RecName: Full=Geranylgeranyl transferase type-2 subunit beta;
DE            EC=2.5.1.60;
DE   AltName: Full=Geranylgeranyl transferase type II subunit beta;
DE            Short=GGTase-II-beta;
DE   AltName: Full=Rab geranyl-geranyltransferase subunit beta;
DE            Short=Rab GG transferase beta;
DE            Short=Rab GGTase beta;
DE   AltName: Full=Rab geranylgeranyltransferase subunit beta;
DE   AltName: Full=Type II protein geranyl-geranyltransferase subunit beta;
GN   Name=RABGGTB; Synonyms=GGTB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004663; F:Rab geranylgeranyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0018344; P:protein geranylgeranylation; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PH4H_HUMAN              Reviewed;         452 AA.
AC   P00439; Q16717; Q8TC14;
DE   RecName: Full=Phenylalanine-4-hydroxylase;
DE            Short=PAH;
DE            EC=1.14.16.1;
DE   AltName: Full=Phe-4-monooxygenase;
GN   Name=PAH;
DR   GuidetoPHARMACOLOGY; 1240; -.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004505; F:phenylalanine 4-monooxygenase activity; EXP:Reactome.
DR   GO; GO:0042423; P:catecholamine biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; NAS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PHAG1_HUMAN             Reviewed;         432 AA.
AC   Q9NWQ8; A8K1A3; Q2M1Z9; Q5BKU4; Q9NYK0;
DE   RecName: Full=Phosphoprotein associated with glycosphingolipid-enriched microdomains 1;
DE   AltName: Full=Csk-binding protein;
DE   AltName: Full=Transmembrane adapter protein PAG;
DE   AltName: Full=Transmembrane phosphoprotein Cbp;
GN   Name=PAG1; Synonyms=CBP, PAG;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:HGNC.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; NAS:HGNC.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; NAS:GOC.
DR   GO; GO:0050863; P:regulation of T cell activation; IDA:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   PHAR1_HUMAN             Reviewed;         580 AA.
AC   Q9C0D0; A8K1V2; Q3MJ93; Q5JSJ2;
DE   RecName: Full=Phosphatase and actin regulator 1;
GN   Name=PHACTR1; Synonyms=KIAA1733, RPEL1;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.
DR   GO; GO:0048870; P:cell motility; IMP:UniProtKB.
DR   GO; GO:0043149; P:stress fiber assembly; IMP:UniProtKB.
//
ID   PHAR2_HUMAN             Reviewed;         634 AA.
AC   O75167; A6NKP5; A7MCZ5; A8MZC0; B2RWP7; B4DN76; B4DPB5; B4DTH7;
AC   Q5TFA0; Q68DM2;
DE   RecName: Full=Phosphatase and actin regulator 2;
GN   Name=PHACTR2; Synonyms=C6orf56, KIAA0680;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
//
ID   PHAR3_HUMAN             Reviewed;         559 AA.
AC   Q96KR7; B1AKX0; B1AN68; B1AN69; B2RB46; Q32P33; Q707P6; Q9H4T4;
DE   RecName: Full=Phosphatase and actin regulator 3;
DE   AltName: Full=Scaffold-associated PP1-inhibiting protein;
DE            Short=Scapinin;
GN   Name=PHACTR3; Synonyms=C20orf101, SCAPIN1;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
//
ID   PHAR4_HUMAN             Reviewed;         702 AA.
AC   Q8IZ21; A2APK6; B9ZVW0; D3DPM3; Q68DD4; Q6NUN6; Q8N384; Q9H395;
AC   Q9H6X0; Q9H8W6;
DE   RecName: Full=Phosphatase and actin regulator 4;
GN   Name=PHACTR4; ORFNames=PRO2963;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.
DR   GO; GO:0071862; F:protein phosphatase type 1 activator activity; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0061386; P:closure of optic fissure; ISS:UniProtKB.
DR   GO; GO:0048484; P:enteric nervous system development; ISS:UniProtKB.
DR   GO; GO:2001045; P:negative regulation of integrin-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; ISS:UniProtKB.
//
ID   PHAX_HUMAN              Reviewed;         394 AA.
AC   Q9H814; Q9H8W1;
DE   RecName: Full=Phosphorylated adapter RNA export protein;
DE   AltName: Full=RNA U small nuclear RNA export adapter protein;
GN   Name=PHAX; Synonyms=RNUXA;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015643; F:toxic substance binding; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006408; P:snRNA export from nucleus; TAS:BHF-UCL.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
//
ID   PHB2_HUMAN              Reviewed;         299 AA.
AC   Q99623; B4DP75; Q2YDA4; Q7KYU3; Q92978;
DE   RecName: Full=Prohibitin-2;
DE   AltName: Full=B-cell receptor-associated protein BAP37;
DE   AltName: Full=D-prohibitin;
DE   AltName: Full=Repressor of estrogen receptor activity;
GN   Name=PHB2; Synonyms=BAP, REA;
DR   GO; GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0060744; P:mammary gland branching involved in thelarche; IEA:Ensembl.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHB_HUMAN               Reviewed;         272 AA.
AC   P35232; B4DY47; Q4VBQ0;
DE   RecName: Full=Prohibitin;
GN   Name=PHB;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0071354; P:cellular response to interleukin-6; IDA:BHF-UCL.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0016575; P:histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:2000323; P:negative regulation of glucocorticoid receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   PHC1_HUMAN              Reviewed;        1004 AA.
AC   P78364; D3DUV4; Q8WVM3; Q9BU63;
DE   RecName: Full=Polyhomeotic-like protein 1;
DE            Short=hPH1;
DE   AltName: Full=Early development regulatory protein 1;
GN   Name=PHC1; Synonyms=EDR1, PH1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0016574; P:histone ubiquitination; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   PHC2_HUMAN              Reviewed;         858 AA.
AC   Q8IXK0; A1L4Q1; A8KA40; D3DPR2; Q2TAL3; Q5T0C1; Q6NUJ6; Q6ZQR1;
AC   Q8N306; Q8TAG8; Q96BL4; Q9Y4Y7;
DE   RecName: Full=Polyhomeotic-like protein 2;
DE            Short=hPH2;
DE   AltName: Full=Early development regulatory protein 2;
GN   Name=PHC2; Synonyms=EDR2, PH2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PHC3_HUMAN              Reviewed;         983 AA.
AC   Q8NDX5; A2RRP9; Q5HYF0; Q6NSG2; Q8NFT7; Q8NFZ1; Q8TBM2; Q9H971;
AC   Q9H9I4;
DE   RecName: Full=Polyhomeotic-like protein 3;
DE   AltName: Full=Early development regulatory protein 3;
DE   AltName: Full=Homolog of polyhomeotic 3;
DE            Short=hPH3;
GN   Name=PHC3; Synonyms=EDR3, PH3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   PHEX_HUMAN              Reviewed;         749 AA.
AC   P78562; O00678; Q13646; Q2M325; Q93032; Q99827;
DE   RecName: Full=Phosphate-regulating neutral endopeptidase;
DE            EC=3.4.24.-;
DE   AltName: Full=Metalloendopeptidase homolog PEX;
DE   AltName: Full=Vitamin D-resistant hypophosphatemic rickets protein;
DE   AltName: Full=X-linked hypophosphatemia protein;
DE            Short=HYP;
GN   Name=PHEX; Synonyms=PEX;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0019637; P:organophosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   PHF10_HUMAN             Reviewed;         498 AA.
AC   Q8WUB8; Q2YDA3; Q53HG8; Q9BXD2; Q9NV26;
DE   RecName: Full=PHD finger protein 10;
DE   AltName: Full=BRG1-associated factor 45a;
DE            Short=BAF45a;
DE   AltName: Full=XAP135;
GN   Name=PHF10; Synonyms=BAF45A;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF11_HUMAN             Reviewed;         331 AA.
AC   Q9UIL8; Q5W0A4; Q5W0A6; Q9Y5A2;
DE   RecName: Full=PHD finger protein 11;
DE   AltName: Full=BRCA1 C-terminus-associated protein;
DE   AltName: Full=Renal carcinoma antigen NY-REN-34;
GN   Name=PHF11; Synonyms=BCAP;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF12_HUMAN             Reviewed;        1004 AA.
AC   Q96QT6; Q0VAI5; Q6ZML2; Q9BV34; Q9H7U9; Q9P205;
DE   RecName: Full=PHD finger protein 12;
DE   AltName: Full=PHD factor 1;
DE            Short=Pf1;
GN   Name=PHF12; Synonyms=KIAA1523;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
//
ID   PHF13_HUMAN             Reviewed;         300 AA.
AC   Q86YI8; B3KUQ7; Q59FB6; Q5TH65; Q8N551; Q9UJP2;
DE   RecName: Full=PHD finger protein 13;
DE   AltName: Full=Survival time-associated PHD finger protein in ovarian cancer 1;
DE            Short=SPOC1;
GN   Name=PHF13;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IMP:UniProtKB.
//
ID   PHF14_HUMAN             Reviewed;         888 AA.
AC   O94880; A7MCZ3; B4DI82;
DE   RecName: Full=PHD finger protein 14;
GN   Name=PHF14; Synonyms=KIAA0783;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PHF19_HUMAN             Reviewed;         580 AA.
AC   Q5T6S3; Q32NF2; Q5T6S4; Q6N038; Q8TBL6; Q9UFS9;
DE   RecName: Full=PHD finger protein 19;
DE   AltName: Full=Polycomb-like protein 3;
DE            Short=hPCL3;
GN   Name=PHF19; Synonyms=PCL3;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0061087; P:positive regulation of histone H3-K27 methylation; IMP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF1_HUMAN              Reviewed;         567 AA.
AC   O43189; B1AZX2; B1AZX3; O60929; Q5SU07; Q5SU08; Q96KM7;
DE   RecName: Full=PHD finger protein 1;
DE            Short=Protein PHF1;
DE            Short=hPHF1;
DE   AltName: Full=Polycomb-like protein 1;
DE            Short=hPCl1;
GN   Name=PHF1; Synonyms=PCL1;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0061086; P:negative regulation of histone H3-K27 methylation; IMP:UniProtKB.
DR   GO; GO:0061087; P:positive regulation of histone H3-K27 methylation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF20_HUMAN             Reviewed;        1012 AA.
AC   Q9BVI0; A7E235; B2RB56; E1P5S3; Q566Q2; Q5JWY9; Q66K49; Q9BWV4;
AC   Q9BXA3; Q9BZW3; Q9H421; Q9H4J6; Q9NZ22;
DE   RecName: Full=PHD finger protein 20;
DE   AltName: Full=Glioma-expressed antigen 2;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 58;
DE   AltName: Full=Novel zinc finger protein;
DE   AltName: Full=Transcription factor TZP;
GN   Name=PHF20; Synonyms=C20orf104, GLEA2, HCA58, NZF, TZP;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF23_HUMAN             Reviewed;         403 AA.
AC   Q9BUL5; A1DZ74; D3DTN4; Q8IZK0; Q96HG7; Q9H5X0;
DE   RecName: Full=PHD finger protein 23;
DE   AltName: Full=PDH-containing protein JUNE-1;
GN   Name=PHF23;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PHF2_HUMAN              Reviewed;        1096 AA.
AC   O75151; Q4VXG0; Q8N3K2; Q9Y6N4;
DE   RecName: Full=Lysine-specific demethylase PHF2;
DE            EC=1.14.11.-;
DE   AltName: Full=GRC5;
DE   AltName: Full=PHD finger protein 2;
GN   Name=PHF2; Synonyms=KIAA0662;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0001889; P:liver development; TAS:UniProtKB.
DR   GO; GO:0061188; P:negative regulation of chromatin silencing at rDNA; IMP:UniProtKB.
DR   GO; GO:0006482; P:protein demethylation; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF3_HUMAN              Reviewed;        2039 AA.
AC   Q92576; A3KFI8; Q14CR5; Q5CZI1; Q5T1T6; Q9NQ16; Q9UI45;
DE   RecName: Full=PHD finger protein 3;
GN   Name=PHF3; Synonyms=KIAA0244;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   PHF5A_HUMAN             Reviewed;         110 AA.
AC   Q7RTV0; Q9UH06;
DE   RecName: Full=PHD finger-like domain-containing protein 5A;
DE            Short=PHD finger-like domain protein 5A;
DE   AltName: Full=Splicing factor 3B-associated 14 kDa protein;
DE            Short=SF3b14b;
GN   Name=PHF5A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF6_HUMAN              Reviewed;         365 AA.
AC   Q8IWS0; A8K230; B4E0G4; D3DTG3; E9PC97; Q5JRC7; Q5JRC8; Q96JK3;
AC   Q9BRU0;
DE   RecName: Full=PHD finger protein 6;
DE   AltName: Full=PHD-like zinc finger protein;
GN   Name=PHF6; Synonyms=KIAA1823;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProt.
DR   GO; GO:0042393; F:histone binding; IPI:UniProt.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProt.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProt.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:UniProt.
DR   GO; GO:0015631; F:tubulin binding; IPI:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHF7_HUMAN              Reviewed;         381 AA.
AC   Q9BWX1; K4DI82;
DE   RecName: Full=PHD finger protein 7;
DE   AltName: Full=Testis development protein NYD-SP6;
GN   Name=PHF7;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PHF8_HUMAN              Reviewed;        1060 AA.
AC   Q9UPP1; B3KMV4; B7Z911; Q5H9U5; Q5JPR9; Q5JPS0; Q5JPS2; Q5JPS3;
AC   Q5VUJ4; Q7Z6D4; Q9HAH2;
DE   RecName: Full=Histone lysine demethylase PHF8;
DE            EC=1.14.11.27;
DE   AltName: Full=PHD finger protein 8;
GN   Name=PHF8; Synonyms=KIAA1111, ZNF422;
DR   GuidetoPHARMACOLOGY; 2698; -.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0032452; F:histone demethylase activity; IDA:UniProtKB.
DR   GO; GO:0071558; F:histone demethylase activity (H3-K27 specific); IDA:UniProtKB.
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.
DR   GO; GO:0032454; F:histone demethylase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0035575; F:histone demethylase activity (H4-K20 specific); IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0071557; P:histone H3-K27 demethylation; IDA:UniProtKB.
DR   GO; GO:0070544; P:histone H3-K36 demethylation; IDA:UniProtKB.
DR   GO; GO:0033169; P:histone H3-K9 demethylation; IDA:UniProtKB.
DR   GO; GO:0035574; P:histone H4-K20 demethylation; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0061188; P:negative regulation of chromatin silencing at rDNA; IDA:UniProtKB.
DR   GO; GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHGR1_HUMAN             Reviewed;          82 AA.
AC   C9JFL3;
DE   RecName: Full=Proline, histidine and glycine-rich protein 1;
GN   Name=PHGR1;
//
ID   PHIPL_HUMAN             Reviewed;         376 AA.
AC   Q96FC7; B7WP61; Q68DF3; Q6UXY3; Q8N3W3; Q96JM9; Q96NP7;
DE   RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein-like;
GN   Name=PHYHIPL; Synonyms=KIAA1796; ORFNames=UNQ6309/PRO20934;
//
ID   PHIP_HUMAN              Reviewed;        1821 AA.
AC   Q8WWQ0; A7J992; B2RPK4; Q05CQ9; Q5VVH4; Q66I29; Q69YV1; Q8NBZ5;
AC   Q96H52; Q96ME2; Q9H261;
DE   RecName: Full=PH-interacting protein;
DE            Short=PHIP;
DE   AltName: Full=IRS-1 PH domain-binding protein;
DE   AltName: Full=WD repeat-containing protein 11;
GN   Name=PHIP; Synonyms=WDR11;
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005158; F:insulin receptor binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
//
ID   PHKG1_HUMAN             Reviewed;         387 AA.
AC   Q16816; B7Z1D0; F5H2S1; Q75LP5;
DE   RecName: Full=Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform;
DE            Short=PHK-gamma-M;
DE            EC=2.7.11.19;
DE   AltName: Full=Phosphorylase kinase subunit gamma-1;
DE   AltName: Full=Serine/threonine-protein kinase PHKG1;
DE            EC=2.7.11.1;
DE            EC=2.7.11.26;
GN   Name=PHKG1; Synonyms=PHKG;
DR   GuidetoPHARMACOLOGY; 2145; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004689; F:phosphorylase kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050321; F:tau-protein kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PHKG2_HUMAN             Reviewed;         406 AA.
AC   P15735; A8K0C7; B4DEB7; E9PEU3; P11800;
DE   RecName: Full=Phosphorylase b kinase gamma catalytic chain, liver/testis isoform;
DE            Short=PHK-gamma-LT;
DE            Short=PHK-gamma-T;
DE            EC=2.7.11.19;
DE   AltName: Full=PSK-C3;
DE   AltName: Full=Phosphorylase kinase subunit gamma-2;
GN   Name=PHKG2;
DR   GuidetoPHARMACOLOGY; 2147; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004689; F:phosphorylase kinase activity; TAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:InterPro.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; TAS:ProtInc.
DR   GO; GO:0045819; P:positive regulation of glycogen catabolic process; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PHLA1_HUMAN             Reviewed;         401 AA.
AC   Q8WV24; A1A4G9; Q15184; Q2TAN2; Q9NZ17;
DE   RecName: Full=Pleckstrin homology-like domain family A member 1;
DE   AltName: Full=Apoptosis-associated nuclear protein;
DE   AltName: Full=Proline- and glutamine-rich protein;
DE            Short=PQ-rich protein;
DE            Short=PQR protein;
DE   AltName: Full=Proline- and histidine-rich protein;
DE   AltName: Full=T-cell death-associated gene 51 protein;
GN   Name=PHLDA1; Synonyms=PHRIP, TDAG51;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0045210; P:FasL biosynthetic process; IEA:Ensembl.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
//
ID   PHLA2_HUMAN             Reviewed;         152 AA.
AC   Q53GA4; O00496;
DE   RecName: Full=Pleckstrin homology-like domain family A member 2;
DE   AltName: Full=Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein;
DE   AltName: Full=Imprinted in placenta and liver protein;
DE   AltName: Full=Tumor-suppressing STF cDNA 3 protein;
DE   AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein;
DE   AltName: Full=p17-Beckwith-Wiedemann region 1 C;
DE            Short=p17-BWR1C;
GN   Name=PHLDA2; Synonyms=BWR1C, HLDA2, IPL, TSSC3;
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0045995; P:regulation of embryonic development; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0070873; P:regulation of glycogen metabolic process; IEA:Ensembl.
//
ID   PHLB1_HUMAN             Reviewed;        1377 AA.
AC   Q86UU1; B0YJ63; B0YJ64; O75133; Q4KMF8; Q8TEQ2;
DE   RecName: Full=Pleckstrin homology-like domain family B member 1;
DE   AltName: Full=Protein LL5-alpha;
GN   Name=PHLDB1; Synonyms=KIAA0638, LL5A; ORFNames=DLNB07;
//
ID   PHLA3_HUMAN             Reviewed;         127 AA.
AC   Q9Y5J5; B2R5A4; Q53HD6; Q8NBW9;
DE   RecName: Full=Pleckstrin homology-like domain family A member 3;
DE   AltName: Full=TDAG51/Ipl homolog 1;
GN   Name=PHLDA3; Synonyms=TIH1;
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
//
ID   PHLB2_HUMAN             Reviewed;        1253 AA.
AC   Q86SQ0; A5PKZ3; Q59EA8; Q68CY3; Q6NT98; Q8N8U8; Q8NAB1; Q8NCU5;
DE   RecName: Full=Pleckstrin homology-like domain family B member 2;
DE   AltName: Full=Protein LL5-beta;
GN   Name=PHLDB2; Synonyms=LL5B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PHLB3_HUMAN             Reviewed;         640 AA.
AC   Q6NSJ2; Q8N7Z4;
DE   RecName: Full=Pleckstrin homology-like domain family B member 3;
GN   Name=PHLDB3;
//
ID   PHLD_HUMAN              Reviewed;         840 AA.
AC   P80108; Q15127; Q15128; Q2M2F2; Q5T3Y0; Q7Z6T8; Q8TCV0; Q8WW82;
AC   Q96ID6; Q9H167; Q9H4M1; Q9UJC9;
DE   RecName: Full=Phosphatidylinositol-glycan-specific phospholipase D;
DE            Short=PI-G PLD;
DE            EC=3.1.4.50;
DE   AltName: Full=Glycoprotein phospholipase D;
DE   AltName: Full=Glycosyl-phosphatidylinositol-specific phospholipase D;
DE            Short=GPI-PLD;
DE            Short=GPI-specific phospholipase D;
DE   Flags: Precursor;
GN   Name=GPLD1; Synonyms=PIGPLD1;
DR   GO; GO:0004621; F:glycosylphosphatidylinositol phospholipase D activity; IDA:UniProtKB.
DR   GO; GO:0004630; F:phospholipase D activity; IDA:UniProtKB.
DR   GO; GO:0017080; F:sodium channel regulator activity; ISS:UniProtKB.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0071397; P:cellular response to cholesterol; IMP:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0071467; P:cellular response to pH; IDA:UniProtKB.
DR   GO; GO:0071401; P:cellular response to triglyceride; IMP:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0002430; P:complement receptor mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006507; P:GPI anchor release; IDA:UniProtKB.
DR   GO; GO:0035701; P:hematopoietic stem cell migration; TAS:UniProtKB.
DR   GO; GO:0097241; P:hematopoietic stem cell migration to bone marrow; TAS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010897; P:negative regulation of triglyceride catabolic process; ISS:UniProtKB.
DR   GO; GO:0001503; P:ossification; ISS:UniProtKB.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; ISS:UniProtKB.
DR   GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045919; P:positive regulation of cytolysis; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0010907; P:positive regulation of glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0010983; P:positive regulation of high-density lipoprotein particle clearance; ISS:UniProtKB.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0051047; P:positive regulation of secretion; ISS:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.
DR   GO; GO:1900076; P:regulation of cellular response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0009749; P:response to glucose; IDA:UniProtKB.
DR   GO; GO:0070633; P:transepithelial transport; ISS:UniProtKB.
//
ID   PHLP1_HUMAN             Reviewed;        1717 AA.
AC   O60346; A1A4F5; Q641Q7; Q6P4C4; Q6PJI6; Q86TN6; Q96FK2; Q9NUY1;
DE   RecName: Full=PH domain leucine-rich repeat-containing protein phosphatase 1;
DE            EC=3.1.3.16;
DE   AltName: Full=Pleckstrin homology domain-containing family E member 1;
DE            Short=PH domain-containing family E member 1;
DE   AltName: Full=Suprachiasmatic nucleus circadian oscillatory protein;
DE            Short=hSCOP;
GN   Name=PHLPP1; Synonyms=KIAA0606, PHLPP, PLEKHE1, SCOP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0009649; P:entrainment of circadian clock; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
//
ID   PHLP2_HUMAN             Reviewed;        1323 AA.
AC   Q6ZVD8; A1L374; Q9NV17; Q9Y2E3;
DE   RecName: Full=PH domain leucine-rich repeat-containing protein phosphatase 2;
DE            EC=3.1.3.16;
DE   AltName: Full=PH domain leucine-rich repeat-containing protein phosphatase-like;
DE            Short=PHLPP-like;
GN   Name=PHLPP2; Synonyms=KIAA0931, PHLPPL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
//
ID   PHLP_HUMAN              Reviewed;         301 AA.
AC   Q13371; Q4VXB6; Q96AF1; Q9UEW7; Q9UFL0; Q9UNX1; Q9UNX2;
DE   RecName: Full=Phosducin-like protein;
DE            Short=PHLP;
GN   Name=PDCL; Synonyms=PHLOP1, PhLP1;
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0061084; P:negative regulation of protein refolding; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   PHOCN_HUMAN             Reviewed;         225 AA.
AC   Q9Y3A3; B4DML0; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y4T8;
DE   RecName: Full=MOB-like protein phocein;
DE   AltName: Full=2C4D;
DE   AltName: Full=Class II mMOB1;
DE   AltName: Full=Mob1 homolog 3;
DE            Short=Mob3;
DE   AltName: Full=Mps one binder kinase activator-like 3;
DE   AltName: Full=Preimplantation protein 3;
GN   Name=MOB4; Synonyms=MOB3, MOBKL3, PHOCN, PREI3; ORFNames=CGI-95;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   PHOP1_HUMAN             Reviewed;         267 AA.
AC   Q8TCT1; E9PAM0; Q17RU6;
DE   RecName: Full=Phosphoethanolamine/phosphocholine phosphatase;
DE            EC=3.1.3.75;
GN   Name=PHOSPHO1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0052731; F:phosphocholine phosphatase activity; EXP:Reactome.
DR   GO; GO:0052732; F:phosphoethanolamine phosphatase activity; EXP:Reactome.
DR   GO; GO:0016462; F:pyrophosphatase activity; IDA:MGI.
DR   GO; GO:0035630; P:bone mineralization involved in bone maturation; IEA:Ensembl.
DR   GO; GO:0016311; P:dephosphorylation; EXP:GOC.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030500; P:regulation of bone mineralization; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PHOP2_HUMAN             Reviewed;         241 AA.
AC   Q8TCD6; B2RC30; D3DPC7;
DE   RecName: Full=Pyridoxal phosphate phosphatase PHOSPHO2;
DE            EC=3.1.3.74;
GN   Name=PHOSPHO2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0033883; F:pyridoxal phosphatase activity; IEA:UniProtKB-EC.
//
ID   PHOS_HUMAN              Reviewed;         246 AA.
AC   P20941; Q14816; Q9UP22; Q9UP23;
DE   RecName: Full=Phosducin;
DE            Short=PHD;
DE   AltName: Full=33 kDa phototransducing protein;
DE   AltName: Full=Protein MEKA;
GN   Name=PDC;
DR   GO; GO:0004859; F:phospholipase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007602; P:phototransduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   PHP14_HUMAN             Reviewed;         125 AA.
AC   Q9NRX4; B1AMX0; B1AMX1; Q9H0Y3;
DE   RecName: Full=14 kDa phosphohistidine phosphatase;
DE            EC=3.1.3.-;
DE   AltName: Full=Phosphohistidine phosphatase 1;
DE   AltName: Full=Protein janus-A homolog;
GN   Name=PHPT1; Synonyms=PHP14; ORFNames=CGI-202, HSPC141;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0008969; F:phosphohistidine phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:2000984; P:negative regulation of ATP citrate synthase activity; IDA:BHF-UCL.
DR   GO; GO:0051350; P:negative regulation of lyase activity; IDA:BHF-UCL.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035971; P:peptidyl-histidine dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:2000147; P:positive regulation of cell motility; IMP:BHF-UCL.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; IMP:BHF-UCL.
//
ID   PHRF1_HUMAN             Reviewed;        1649 AA.
AC   Q9P1Y6; A6H8W1; B7ZM64; B9EGP0; C9JS82; Q6PJP2; Q8IVY2; Q8N2Y7;
AC   Q9BSM2;
DE   RecName: Full=PHD and RING finger domain-containing protein 1;
GN   Name=PHRF1; Synonyms=KIAA1542;
DR   GO; GO:0070063; F:RNA polymerase binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   PHS2_HUMAN              Reviewed;         130 AA.
AC   Q9H0N5; Q8TD40;
DE   RecName: Full=Pterin-4-alpha-carbinolamine dehydratase 2;
DE            Short=PHS 2;
DE            EC=4.2.1.96;
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase 2;
DE   AltName: Full=DcoH-like protein DCoHm;
DE   AltName: Full=Dimerization cofactor of hepatocyte nuclear factor 1 from muscle;
DE   AltName: Full=HNF-1-alpha dimerization cofactor;
GN   Name=PCBD2; Synonyms=DCOH2, DCOHM;
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004505; F:phenylalanine 4-monooxygenase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:UniProtKB-KW.
//
ID   PHS_HUMAN               Reviewed;         104 AA.
AC   P61457; P70519; P80095; Q9D930;
DE   RecName: Full=Pterin-4-alpha-carbinolamine dehydratase;
DE            Short=PHS;
DE            EC=4.2.1.96;
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase;
DE   AltName: Full=Dimerization cofactor of hepatocyte nuclear factor 1-alpha;
DE            Short=DCoH;
DE            Short=Dimerization cofactor of HNF1;
DE   AltName: Full=Phenylalanine hydroxylase-stimulating protein;
DE   AltName: Full=Pterin carbinolamine dehydratase;
DE            Short=PCD;
GN   Name=PCBD1; Synonyms=DCOH, PCBD;
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; EXP:Reactome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004505; F:phenylalanine 4-monooxygenase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHTF1_HUMAN             Reviewed;         762 AA.
AC   Q9UMS5; Q5VWP7; Q5VWP8; Q9BUP2; Q9H1X8;
DE   RecName: Full=Putative homeodomain transcription factor 1;
GN   Name=PHTF1; Synonyms=PHTF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHTF2_HUMAN             Reviewed;         785 AA.
AC   Q8N3S3; A0JP04; A0JP05; A4D1C2; E9PEE3; G5E9H7; Q6NW35; Q8TBW4;
AC   Q9H099;
DE   RecName: Full=Putative homeodomain transcription factor 2;
GN   Name=PHTF2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHX2A_HUMAN             Reviewed;         284 AA.
AC   O14813; A8K3N0; Q8IVZ2;
DE   RecName: Full=Paired mesoderm homeobox protein 2A;
DE   AltName: Full=ARIX1 homeodomain protein;
DE   AltName: Full=Aristaless homeobox protein homolog;
DE   AltName: Full=Paired-like homeobox 2A;
GN   Name=PHOX2A; Synonyms=ARIX, PMX2A;
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IC:BHF-UCL.
DR   GO; GO:0021703; P:locus ceruleus development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0003357; P:noradrenergic neuron differentiation; NAS:BHF-UCL.
DR   GO; GO:0021623; P:oculomotor nerve formation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0043576; P:regulation of respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0021523; P:somatic motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021642; P:trochlear nerve formation; IEA:Ensembl.
//
ID   PHX2B_HUMAN             Reviewed;         314 AA.
AC   Q99453; Q6PJD9;
DE   RecName: Full=Paired mesoderm homeobox protein 2B;
DE   AltName: Full=Neuroblastoma Phox;
DE            Short=NBPhox;
DE   AltName: Full=PHOX2B homeodomain protein;
DE   AltName: Full=Paired-like homeobox 2B;
GN   Name=PHOX2B; Synonyms=PMX2B;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048483; P:autonomic nervous system development; IMP:BHF-UCL.
DR   GO; GO:0003360; P:brainstem development; IEP:BHF-UCL.
DR   GO; GO:0021533; P:cell differentiation in hindbrain; ISS:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; ISS:BHF-UCL.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0048894; P:efferent axon development in a lateral line nerve; ISS:BHF-UCL.
DR   GO; GO:0048484; P:enteric nervous system development; IEP:BHF-UCL.
DR   GO; GO:0010001; P:glial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0021934; P:hindbrain tangential cell migration; ISS:BHF-UCL.
DR   GO; GO:0048839; P:inner ear development; ISS:BHF-UCL.
DR   GO; GO:0021723; P:medullary reticular formation development; ISS:BHF-UCL.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:1901166; P:neural crest cell migration involved in autonomic nervous system development; ISS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; ISS:BHF-UCL.
DR   GO; GO:0003358; P:noradrenergic neuron development; ISS:UniProtKB.
DR   GO; GO:0003357; P:noradrenergic neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0048486; P:parasympathetic nervous system development; ISS:BHF-UCL.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; ISS:BHF-UCL.
DR   GO; GO:0060541; P:respiratory system development; ISS:BHF-UCL.
DR   GO; GO:0061452; P:retrotrapezoid nucleus neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PHYD1_HUMAN             Reviewed;         291 AA.
AC   Q5SRE7; A6PWN9; A6PWP0; B3KT57; B4E3X8; Q5SRE9; Q5SRF0; Q7Z623;
AC   Q7Z7P9; Q96GM4;
DE   RecName: Full=Phytanoyl-CoA dioxygenase domain-containing protein 1;
DE            EC=1.-.-.-;
GN   Name=PHYHD1;
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   PHYIP_HUMAN             Reviewed;         330 AA.
AC   Q92561; D3DSR1; Q8N4I9;
DE   RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein;
DE   AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1;
DE            Short=PAHX-AP1;
DE            Short=PAHXAP1;
GN   Name=PHYHIP; Synonyms=DYRK1AP3, KIAA0273;
//
ID   PI15_HUMAN              Reviewed;         258 AA.
AC   O43692; Q68CY1;
DE   RecName: Full=Peptidase inhibitor 15;
DE            Short=PI-15;
DE   AltName: Full=25 kDa trypsin inhibitor;
DE            Short=p25TI;
DE   AltName: Full=Cysteine-rich secretory protein 8;
DE            Short=CRISP-8;
DE   AltName: Full=SugarCrisp;
DE   Flags: Precursor;
GN   Name=PI15; Synonyms=CRISP8, P25TI;
DR   GO; GO:0030414; F:peptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   PI16_HUMAN              Reviewed;         463 AA.
AC   Q6UXB8; Q6ZVG9; Q8IYL8; Q8NBK0; Q8TCB8;
DE   RecName: Full=Peptidase inhibitor 16;
DE            Short=PI-16;
DE   AltName: Full=Cysteine-rich secretory protein 9;
DE            Short=CRISP-9;
DE   AltName: Full=PSP94-binding protein;
DE   Flags: Precursor;
GN   Name=PI16; Synonyms=CRISP9, PSPBP; ORFNames=PSEC0164, UNQ289/PRO328;
DR   GO; GO:0030414; F:peptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   PI2R_HUMAN              Reviewed;         386 AA.
AC   P43119;
DE   RecName: Full=Prostacyclin receptor;
DE   AltName: Full=Prostaglandin I2 receptor;
DE            Short=PGI receptor;
DE            Short=PGI2 receptor;
DE   AltName: Full=Prostanoid IP receptor;
DE   Flags: Precursor;
GN   Name=PTGIR; Synonyms=PRIPR;
DR   GuidetoPHARMACOLOGY; 345; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IMP:BHF-UCL.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   PI3R4_HUMAN             Reviewed;        1358 AA.
AC   Q99570; Q2TBF4;
DE   RecName: Full=Phosphoinositide 3-kinase regulatory subunit 4;
DE            Short=PI3-kinase regulatory subunit 4;
DE            EC=2.7.11.1;
DE   AltName: Full=PI3-kinase p150 subunit;
DE   AltName: Full=Phosphoinositide 3-kinase adaptor protein;
GN   Name=PIK3R4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   PI3R5_HUMAN             Reviewed;         880 AA.
AC   Q8WYR1; B0LPH4; D3DTS3; Q5G936; Q5G938; Q5G939; Q8IZ23; Q9Y2Y2;
DE   RecName: Full=Phosphoinositide 3-kinase regulatory subunit 5;
DE            Short=PI3-kinase regulatory subunit 5;
DE   AltName: Full=PI3-kinase p101 subunit;
DE   AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit;
DE            Short=PtdIns-3-kinase regulatory subunit;
DE   AltName: Full=Protein FOAP-2;
DE   AltName: Full=PtdIns-3-kinase p101;
DE   AltName: Full=p101-PI3K;
GN   Name=PIK3R5;
DR   GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI42A_HUMAN             Reviewed;         406 AA.
AC   P48426; B0YJ66; D3DRV1; P53807; Q5VUX3;
DE   RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha;
DE            EC=2.7.1.149;
DE   AltName: Full=1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha;
DE   AltName: Full=Diphosphoinositide kinase 2-alpha;
DE   AltName: Full=PIP5KIII;
DE   AltName: Full=Phosphatidylinositol 5-phosphate 4-kinase type II alpha;
DE            Short=PI(5)P 4-kinase type II alpha;
DE            Short=PIP4KII-alpha;
DE   AltName: Full=PtdIns(4)P-5-kinase B isoform;
DE   AltName: Full=PtdIns(4)P-5-kinase C isoform;
DE   AltName: Full=PtdIns(5)P-4-kinase isoform 2-alpha;
GN   Name=PIP4K2A; Synonyms=PIP5K2, PIP5K2A;
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; NAS:UniProtKB.
DR   GO; GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; NAS:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI42B_HUMAN             Reviewed;         416 AA.
AC   P78356; Q5U0E8; Q8TBP2;
DE   RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 beta;
DE            EC=2.7.1.149;
DE   AltName: Full=1-phosphatidylinositol 5-phosphate 4-kinase 2-beta;
DE   AltName: Full=Diphosphoinositide kinase 2-beta;
DE   AltName: Full=Phosphatidylinositol 5-phosphate 4-kinase type II beta;
DE            Short=PI(5)P 4-kinase type II beta;
DE            Short=PIP4KII-beta;
DE   AltName: Full=PtdIns(5)P-4-kinase isoform 2-beta;
GN   Name=PIP4K2B; Synonyms=PIP5K2B;
DR   GuidetoPHARMACOLOGY; 2162; -.
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:MGI.
DR   GO; GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IDA:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI3R6_HUMAN             Reviewed;         754 AA.
AC   Q5UE93; Q658R3;
DE   RecName: Full=Phosphoinositide 3-kinase regulatory subunit 6;
DE   AltName: Full=Phosphoinositide 3-kinase gamma adapter protein of 87 kDa;
DE   AltName: Full=p84 PI3K adapter protein;
DE            Short=p84 PIKAP;
DE   AltName: Full=p87 PI3K adapter protein;
DE            Short=p87PIKAP;
GN   Name=PIK3R6; Synonyms=C17orf38;
DR   GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; ISS:UniProtKB.
DR   GO; GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; ISS:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0043551; P:regulation of phosphatidylinositol 3-kinase activity; ISS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI42C_HUMAN             Reviewed;         421 AA.
AC   Q8TBX8; B2RDL3; B4DM11; B4DY44; Q9H6N2;
DE   RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma;
DE            EC=2.7.1.149;
DE   AltName: Full=Phosphatidylinositol 5-phosphate 4-kinase type II gamma;
DE            Short=PI(5)P 4-kinase type II gamma;
DE            Short=PIP4KII-gamma;
GN   Name=PIP4K2C; Synonyms=PIP5K2C;
DR   GuidetoPHARMACOLOGY; 2163; -.
DR   GO; GO:0016309; F:1-phosphatidylinositol-5-phosphate 4-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
//
ID   PI4KA_HUMAN             Reviewed;        2044 AA.
AC   P42356; Q7Z625; Q9UPG2;
DE   RecName: Full=Phosphatidylinositol 4-kinase alpha;
DE            Short=PI4-kinase alpha;
DE            Short=PI4K-alpha;
DE            Short=PtdIns-4-kinase alpha;
DE            EC=2.7.1.67;
GN   Name=PI4KA; Synonyms=PIK4, PIK4CA;
DR   GuidetoPHARMACOLOGY; 2148; -.
DR   GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IBA:RefGenome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI4KB_HUMAN             Reviewed;         816 AA.
AC   Q9UBF8; B4DGI2; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6;
DE   RecName: Full=Phosphatidylinositol 4-kinase beta;
DE            Short=PI4K-beta;
DE            Short=PI4Kbeta;
DE            Short=PtdIns 4-kinase beta;
DE            EC=2.7.1.67;
DE   AltName: Full=NPIK;
DE   AltName: Full=PI4K92;
GN   Name=PI4KB; Synonyms=PIK4CB;
DR   GuidetoPHARMACOLOGY; 2149; -.
DR   GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; TAS:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI4P2_HUMAN             Reviewed;         592 AA.
AC   A4QPH2; Q6ICJ0; Q6ZT68; Q8WUK7;
DE   RecName: Full=Putative phosphatidylinositol 4-kinase alpha-like protein P2;
GN   Name=PI4KAP2;
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
//
ID   PI4P1_HUMAN             Reviewed;         262 AA.
AC   Q8N8J0;
DE   RecName: Full=Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1;
GN   Name=PI4KAP1;
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.
//
ID   PI51B_HUMAN             Reviewed;         540 AA.
AC   O14986; A8K9L9; B4DIG7; P78518; P78519; Q5T5K6; Q5T5K8; Q5T5K9;
AC   Q5VZ00; Q7KYT5; Q8NHQ5; Q92749;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 beta;
DE            Short=PIP5K1-beta;
DE            Short=PtdIns(4)P-5-kinase 1 beta;
DE            EC=2.7.1.68;
DE   AltName: Full=Phosphatidylinositol 4-phosphate 5-kinase type I beta;
DE            Short=PIP5KIbeta;
DE   AltName: Full=Protein STM-7;
DE   AltName: Full=Type I phosphatidylinositol 4-phosphate 5-kinase beta;
GN   Name=PIP5K1B; Synonyms=STM7;
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; NAS:GOC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI51A_HUMAN             Reviewed;         562 AA.
AC   Q99755; A8K4Q0; B4DIN0; Q99754; Q99756;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha;
DE            Short=PIP5K1-alpha;
DE            Short=PtdIns(4)P-5-kinase 1 alpha;
DE            EC=2.7.1.68;
DE   AltName: Full=68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha;
DE   AltName: Full=Phosphatidylinositol 4-phosphate 5-kinase type I alpha;
DE            Short=PIP5KIalpha;
GN   Name=PIP5K1A;
DR   GuidetoPHARMACOLOGY; 2164; -.
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019900; F:kinase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
DR   GO; GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0006650; P:glycerophospholipid metabolic process; TAS:ProtInc.
DR   GO; GO:0030216; P:keratinocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; TAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IDA:GOC.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0097178; P:ruffle assembly; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PI51C_HUMAN             Reviewed;         668 AA.
AC   O60331; B7Z9E7; C6GIJ7; C6GIJ8; Q7LE07;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma;
DE            Short=PIP5K1-gamma;
DE            Short=PtdIns(4)P-5-kinase 1 gamma;
DE            EC=2.7.1.68;
DE   AltName: Full=Phosphatidylinositol 4-phosphate 5-kinase type I gamma;
DE            Short=PIP5KIgamma;
GN   Name=PIP5K1C; Synonyms=KIAA0589;
DR   GuidetoPHARMACOLOGY; 2165; -.
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0034333; P:adherens junction assembly; TAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; TAS:UniProtKB.
DR   GO; GO:0072583; P:clathrin-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; TAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; TAS:UniProtKB.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB.
//
ID   PI5L1_HUMAN             Reviewed;         394 AA.
AC   Q5T9C9; Q8IVS3;
DE   RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase-like protein 1;
DE            Short=PI(4)P 5-kinase-like protein 1;
DE            Short=PtdIns(4)P-5-kinase-like protein 1;
DE            EC=2.7.1.68;
GN   Name=PIP5KL1;
DR   GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   PI5PA_HUMAN             Reviewed;        1006 AA.
AC   Q15735; B3KS54; Q32M61; Q6ZTH6; Q8N902; Q9UDT9;
DE   RecName: Full=Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A;
DE            EC=3.1.3.56;
DE   AltName: Full=Inositol polyphosphate 5-phosphatase J;
GN   Name=INPP5J; Synonyms=PIB5PA, PIPP;
DR   GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PIANP_HUMAN             Reviewed;         282 AA.
AC   Q8IYJ0; A8K0T3; B3KPF7; B3KRI6; Q6UX35;
DE   RecName: Full=PILR alpha-associated neural protein;
DE   AltName: Full=PILR-associating neural protein;
DE   AltName: Full=Paired immunoglobin-like type 2 receptor-associating neural protein;
DE   Flags: Precursor;
GN   Name=PIANP; Synonyms=C12orf53, PANP; ORFNames=UNQ828/PRO1755;
//
ID   PIAS1_HUMAN             Reviewed;         651 AA.
AC   O75925; B2RB67; Q147X4; Q99751; Q9UN02;
DE   RecName: Full=E3 SUMO-protein ligase PIAS1;
DE            EC=6.3.2.-;
DE   AltName: Full=DEAD/H box-binding protein 1;
DE   AltName: Full=Gu-binding protein;
DE            Short=GBP;
DE   AltName: Full=Protein inhibitor of activated STAT protein 1;
DE   AltName: Full=RNA helicase II-binding protein;
GN   Name=PIAS1; Synonyms=DDXBP1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0051152; P:positive regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; ISS:UniProtKB.
DR   GO; GO:0065004; P:protein-DNA complex assembly; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PIAS2_HUMAN             Reviewed;         621 AA.
AC   O75928; O75927; Q96BT5; Q96KE3;
DE   RecName: Full=E3 SUMO-protein ligase PIAS2;
DE            EC=6.3.2.-;
DE   AltName: Full=Androgen receptor-interacting protein 3;
DE            Short=ARIP3;
DE   AltName: Full=DAB2-interacting protein;
DE            Short=DIP;
DE   AltName: Full=Msx-interacting zinc finger protein;
DE            Short=Miz1;
DE   AltName: Full=PIAS-NY protein;
DE   AltName: Full=Protein inhibitor of activated STAT x;
DE   AltName: Full=Protein inhibitor of activated STAT2;
GN   Name=PIAS2; Synonyms=PIASX;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PICK1_HUMAN             Reviewed;         415 AA.
AC   Q9NRD5; B3KS52; O95906;
DE   RecName: Full=PRKCA-binding protein;
DE   AltName: Full=Protein interacting with C kinase 1;
DE   AltName: Full=Protein kinase C-alpha-binding protein;
GN   Name=PICK1; Synonyms=PRKCABP;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0071933; F:Arp2/3 complex binding; ISS:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; ISS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0036294; P:cellular response to decreased oxygen levels; ISS:UniProtKB.
DR   GO; GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.
DR   GO; GO:0097062; P:dendritic spine maintenance; ISS:UniProtKB.
DR   GO; GO:0097061; P:dendritic spine organization; ISS:UniProtKB.
DR   GO; GO:0043045; P:DNA methylation involved in embryo development; NAS:UniProtKB.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; TAS:UniProtKB.
DR   GO; GO:0021782; P:glial cell development; ISS:UniProtKB.
DR   GO; GO:0060292; P:long term synaptic depression; ISS:UniProtKB.
DR   GO; GO:0015844; P:monoamine transport; IDA:UniProtKB.
DR   GO; GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0045161; P:neuronal ion channel clustering; TAS:UniProtKB.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0043113; P:receptor clustering; ISS:UniProtKB.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   PIAS3_HUMAN             Reviewed;         628 AA.
AC   Q9Y6X2; Q9UFI3;
DE   RecName: Full=E3 SUMO-protein ligase PIAS3;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein inhibitor of activated STAT protein 3;
GN   Name=PIAS3;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045838; P:positive regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PIBF1_HUMAN             Reviewed;         757 AA.
AC   Q8WXW3; O95664; Q6U9V2; Q6UG50; Q86V07; Q96SF4;
DE   RecName: Full=Progesterone-induced-blocking factor 1;
GN   Name=PIBF1; Synonyms=C13orf24, PIBF;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PICAL_HUMAN             Reviewed;         652 AA.
AC   Q13492; B4DTM3; E9PN05; F8VPG7; O60700; Q4LE54; Q6GMQ6; Q86XZ9;
DE   RecName: Full=Phosphatidylinositol-binding clathrin assembly protein;
DE   AltName: Full=Clathrin assembly lymphoid myeloid leukemia protein;
GN   Name=PICALM; Synonyms=CALM;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0035615; F:clathrin adaptor activity; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProtKB.
DR   GO; GO:0032050; F:clathrin heavy chain binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0034205; P:beta-amyloid formation; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0035459; P:cargo loading into vesicle; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0008283; P:cell proliferation; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0048268; P:clathrin coat assembly; IMP:BHF-UCL.
DR   GO; GO:0072583; P:clathrin-mediated endocytosis; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0016197; P:endosomal transport; IMP:BHF-UCL.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0097459; P:iron ion import into cell; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0048261; P:negative regulation of receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0031623; P:receptor internalization; IMP:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:UniProtKB.
DR   GO; GO:0030100; P:regulation of endocytosis; IMP:BHF-UCL.
DR   GO; GO:1901214; P:regulation of neuron death; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   PIAS4_HUMAN             Reviewed;         510 AA.
AC   Q8N2W9; O75926; Q96G19; Q9UN16;
DE   RecName: Full=E3 SUMO-protein ligase PIAS4;
DE            EC=6.3.2.-;
DE   AltName: Full=PIASy;
DE   AltName: Full=Protein inhibitor of activated STAT protein 4;
DE   AltName: Full=Protein inhibitor of activated STAT protein gamma;
DE            Short=PIAS-gamma;
GN   Name=PIAS4; Synonyms=PIASG;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IMP:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:1902231; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:1902174; P:positive regulation of keratinocyte apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   PIDD_HUMAN              Reviewed;         910 AA.
AC   Q9HB75; Q59FD1; Q59H10; Q59HC7; Q7Z4P8; Q8NC89; Q8NDL2; Q96C25;
AC   Q9NRE6;
DE   RecName: Full=p53-induced protein with a death domain;
DE   AltName: Full=Leucine-rich repeat and death domain-containing protein;
GN   Name=PIDD; Synonyms=LRDD;
DR   GO; GO:0005123; F:death receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PIEZ1_HUMAN             Reviewed;        2521 AA.
AC   Q92508; A6NHT9; A7E2B7; Q0KKZ9;
DE   RecName: Full=Piezo-type mechanosensitive ion channel component 1;
DE   AltName: Full=Membrane protein induced by beta-amyloid treatment;
DE            Short=Mib;
DE   AltName: Full=Protein FAM38A;
GN   Name=PIEZO1; Synonyms=FAM38A, KIAA0233;
DR   GO; GO:0005261; F:cation channel activity; ISS:UniProtKB.
DR   GO; GO:0008381; F:mechanically-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; ISS:UniProtKB.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0033634; P:positive regulation of cell-cell adhesion mediated by integrin; IMP:UniProtKB.
DR   GO; GO:0033625; P:positive regulation of integrin activation; IMP:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
//
ID   PIEZ2_HUMAN             Reviewed;        2752 AA.
AC   Q9H5I5; B7Z812; Q8N787; Q8NAR6; Q9H5R4;
DE   RecName: Full=Piezo-type mechanosensitive ion channel component 2;
DE   AltName: Full=Protein FAM38B;
GN   Name=PIEZO2; Synonyms=C18orf30, C18orf58, FAM38B;
DR   GO; GO:0005261; F:cation channel activity; IEA:Ensembl.
DR   GO; GO:0008381; F:mechanically-gated ion channel activity; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; ISS:UniProtKB.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
//
ID   PIFO_HUMAN              Reviewed;         191 AA.
AC   Q8TCI5; D9J0A2; D9J0A3; Q4G0K4; Q52LJ6; Q5T5D5; Q5T5D6; Q8N310;
DE   RecName: Full=Protein pitchfork;
GN   Name=PIFO; Synonyms=C1orf88;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IMP:UniProtKB.
DR   GO; GO:0031344; P:regulation of cell projection organization; ISS:UniProtKB.
//
ID   PIGA_HUMAN              Reviewed;         484 AA.
AC   P37287; B4E0V2; Q16025; Q16250;
DE   RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit A;
DE            EC=2.4.1.198;
DE   AltName: Full=GlcNAc-PI synthesis protein;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class A protein;
DE            Short=PIG-A;
GN   Name=PIGA;
DR   GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; TAS:Reactome.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; TAS:HGNC.
DR   GO; GO:0009893; P:positive regulation of metabolic process; TAS:HGNC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIF1_HUMAN              Reviewed;         641 AA.
AC   Q9H611; B2RPL7; Q1W5B6; Q330H5; Q33E24;
DE   RecName: Full=ATP-dependent DNA helicase PIF1;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA repair and recombination helicase PIF1;
DE   AltName: Full=PIF1/RRM3 DNA helicase-like protein;
GN   Name=PIF1; Synonyms=C15orf20;
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IDA:HGNC.
DR   GO; GO:0033682; F:ATP-dependent 5'-3' DNA/RNA helicase activity; IDA:BHF-UCL.
DR   GO; GO:0051880; F:G-quadruplex DNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:HGNC.
DR   GO; GO:0017116; F:single-stranded DNA-dependent ATP-dependent DNA helicase activity; IDA:HGNC.
DR   GO; GO:0010521; F:telomerase inhibitor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:HGNC.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; IEA:UniProtKB-HAMAP.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IDA:HGNC.
DR   GO; GO:0032211; P:negative regulation of telomere maintenance via telomerase; IEA:UniProtKB-HAMAP.
DR   GO; GO:0032204; P:regulation of telomere maintenance; IDA:HGNC.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
//
ID   PIGB_HUMAN              Reviewed;         554 AA.
AC   Q92521; Q53FF9; Q8WVN7;
DE   RecName: Full=GPI mannosyltransferase 3;
DE            EC=2.4.1.-;
DE   AltName: Full=GPI mannosyltransferase III;
DE            Short=GPI-MT-III;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class B protein;
DE            Short=PIG-B;
GN   Name=PIGB;
DR   GO; GO:0000030; F:mannosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0097502; P:mannosylation; IDA:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGC_HUMAN              Reviewed;         297 AA.
AC   Q92535; O14491;
DE   RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit C;
DE            EC=2.4.1.198;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class C protein;
DE            Short=PIG-C;
GN   Name=PIGC; Synonyms=GPI2;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGF_HUMAN              Reviewed;         219 AA.
AC   Q07326; Q8WW20;
DE   RecName: Full=Phosphatidylinositol-glycan biosynthesis class F protein;
DE            Short=PIG-F;
DE   AltName: Full=GPI11 homolog;
GN   Name=PIGF;
DR   GO; GO:0004307; F:ethanolaminephosphotransferase activity; TAS:ProtInc.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGH_HUMAN              Reviewed;         188 AA.
AC   Q14442; B2RAA4;
DE   RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit H;
DE            EC=2.4.1.198;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class H protein;
DE            Short=PIG-H;
GN   Name=PIGH;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; TAS:ProtInc.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGL_HUMAN              Reviewed;         252 AA.
AC   Q9Y2B2; A8KA67;
DE   RecName: Full=N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase;
DE            EC=3.5.1.89;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class L protein;
DE            Short=PIG-L;
GN   Name=PIGL;
DR   GO; GO:0000225; F:N-acetylglucosaminylphosphatidylinositol deacetylase activity; NAS:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGG_HUMAN              Reviewed;         983 AA.
AC   Q5H8A4; B4DKC7; Q2TAK5; Q6UX31; Q7L5Y4; Q8N866; Q8NCC9; Q96SY9;
AC   Q9BVT7; Q9NXG5;
DE   RecName: Full=GPI ethanolamine phosphate transferase 2;
DE            EC=2.-.-.-;
DE   AltName: Full=GPI7 homolog;
DE            Short=hGPI7;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class G protein;
DE            Short=PIG-G;
GN   Name=PIGG; Synonyms=GPI7; ORFNames=UNQ1930/PRO4405;
DR   GO; GO:0051267; F:CP2 mannose-ethanolamine phosphotransferase activity; IDA:MGI.
DR   GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; TAS:Reactome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:MGI.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGM_HUMAN              Reviewed;         423 AA.
AC   Q9H3S5;
DE   RecName: Full=GPI mannosyltransferase 1;
DE            EC=2.4.1.-;
DE   AltName: Full=GPI mannosyltransferase I;
DE            Short=GPI-MT-I;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class M protein;
DE            Short=PIG-M;
GN   Name=PIGM;
DR   GO; GO:0000030; F:mannosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGN_HUMAN              Reviewed;         931 AA.
AC   O95427; Q7L8F8; Q8TC01; Q9NT05;
DE   RecName: Full=GPI ethanolamine phosphate transferase 1;
DE            EC=2.-.-.-;
DE   AltName: Full=MCD4 homolog;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class N protein;
DE            Short=PIG-N;
GN   Name=PIGN; Synonyms=MCD4;
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGO_HUMAN              Reviewed;        1089 AA.
AC   Q8TEQ8; B1AML3; Q6P154; Q6UX80; Q8TDS8; Q96CS9; Q9BVN9; Q9Y4B0;
DE   RecName: Full=GPI ethanolamine phosphate transferase 3;
DE            EC=2.-.-.-;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class O protein;
DE            Short=PIG-O;
GN   Name=PIGO; ORFNames=UNQ632/PRO1249;
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGQ_HUMAN              Reviewed;         760 AA.
AC   Q9BRB3; A2IDE1; D3DU52; O14927; Q96G00; Q96S22; Q9UJH4;
DE   RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q;
DE            EC=2.4.1.198;
DE   AltName: Full=N-acetylglucosamyl transferase component GPI1;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class Q protein;
DE            Short=PIG-Q;
GN   Name=PIGQ; Synonyms=GPI1;
DR   GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGP_HUMAN              Reviewed;         158 AA.
AC   P57054; B2RB18; B2RE99; B5BU92; D3DSG7; J3KR75; Q53Y28; Q96KI1;
AC   Q9NZA6;
DE   RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit P;
DE            EC=2.4.1.198;
DE   AltName: Full=Down syndrome critical region protein 5;
DE   AltName: Full=Down syndrome critical region protein C;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class P protein;
DE            Short=PIG-P;
GN   Name=PIGP; Synonyms=DCRC, DSCR5, DSCRC; ORFNames=NPD010;
DR   GO; GO:0017176; F:phosphatidylinositol N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGR_HUMAN              Reviewed;         764 AA.
AC   P01833; Q68D81; Q8IZY7;
DE   RecName: Full=Polymeric immunoglobulin receptor;
DE            Short=PIgR;
DE            Short=Poly-Ig receptor;
DE   AltName: Full=Hepatocellular carcinoma-associated protein TB6;
DE   Contains:
DE     RecName: Full=Secretory component;
DE   Flags: Precursor;
GN   Name=PIGR;
DR   GO; GO:0001792; F:polymeric immunoglobulin receptor activity; IDA:UniProt.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0038093; P:Fc receptor signaling pathway; IDA:UniProt.
DR   GO; GO:0002415; P:immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; IDA:UniProt.
DR   GO; GO:0043113; P:receptor clustering; IDA:UniProt.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   PIGS_HUMAN              Reviewed;         555 AA.
AC   Q96S52; Q6UVX6;
DE   RecName: Full=GPI transamidase component PIG-S;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class S protein;
GN   Name=PIGS; ORFNames=UNQ1873/PRO4316;
DR   GO; GO:0003923; F:GPI-anchor transamidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; TAS:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   PIGT_HUMAN              Reviewed;         578 AA.
AC   Q969N2; B2RND5; B7Z3N1; B7Z7I8; E1P622; G8JLF5; Q2NL69; Q7Z3N7;
AC   Q9BQY7; Q9BQY8; Q9UJG6; Q9Y2Z5;
DE   RecName: Full=GPI transamidase component PIG-T;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class T protein;
DE   Flags: Precursor;
GN   Name=PIGT; ORFNames=CGI-06, PSEC0163, UNQ716/PRO1379;
DR   GO; GO:0003923; F:GPI-anchor transamidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; TAS:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   PIGV_HUMAN              Reviewed;         493 AA.
AC   Q9NUD9; D3DPL2; Q5JYG7; Q5JYG8; Q5JYG9; Q9NX26;
DE   RecName: Full=GPI mannosyltransferase 2;
DE            EC=2.4.1.-;
DE   AltName: Full=GPI mannosyltransferase II;
DE            Short=GPI-MT-II;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class V protein;
DE            Short=PIG-V;
GN   Name=PIGV;
DR   GO; GO:0000030; F:mannosyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0097502; P:mannosylation; IMP:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGU_HUMAN              Reviewed;         435 AA.
AC   Q9H490; Q7Z489; Q8N2F2;
DE   RecName: Full=Phosphatidylinositol glycan anchor biosynthesis class U protein;
DE   AltName: Full=Cell division cycle protein 91-like 1;
DE            Short=Protein CDC91-like 1;
DE   AltName: Full=GPI transamidase component PIG-U;
GN   Name=PIGU; Synonyms=CDC91L1; ORFNames=PSEC0205, UNQ3055/PRO9875;
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; IMP:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:HGNC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0046425; P:regulation of JAK-STAT cascade; IDA:HGNC.
//
ID   PIGW_HUMAN              Reviewed;         504 AA.
AC   Q7Z7B1; Q8N9G3;
DE   RecName: Full=Phosphatidylinositol-glycan biosynthesis class W protein;
DE            Short=PIG-W;
DE            EC=2.3.-.-;
GN   Name=PIGW;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGX_HUMAN              Reviewed;         258 AA.
AC   Q8TBF5; Q9NWZ2;
DE   RecName: Full=Phosphatidylinositol-glycan biosynthesis class X protein;
DE            Short=PIG-X;
DE   Flags: Precursor;
GN   Name=PIGX;
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016254; P:preassembly of GPI anchor in ER membrane; TAS:Reactome.
//
ID   PIGY_HUMAN              Reviewed;          71 AA.
AC   Q3MUY2;
DE   RecName: Full=Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class Y protein;
DE            Short=PIG-Y;
GN   Name=PIGY;
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IDA:MGI.
//
ID   PIHD1_HUMAN             Reviewed;         290 AA.
AC   Q9NWS0; B4DGN7; B4E2X7; Q9BVL0;
DE   RecName: Full=PIH1 domain-containing protein 1;
DE   AltName: Full=Nucleolar protein 17 homolog;
GN   Name=PIH1D1; Synonyms=NOP17;
DR   GO; GO:0000492; P:box C/D snoRNP assembly; IMP:BHF-UCL.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
//
ID   PIGZ_HUMAN              Reviewed;         579 AA.
AC   Q86VD9; Q9H9G6;
DE   RecName: Full=GPI mannosyltransferase 4;
DE            EC=2.4.1.-;
DE   AltName: Full=GPI mannosyltransferase IV;
DE            Short=GPI-MT-IV;
DE   AltName: Full=Phosphatidylinositol-glycan biosynthesis class Z protein;
DE            Short=PIG-Z;
DE   AltName: Full=SMP3 homolog;
DE            Short=hSMP3;
GN   Name=PIGZ; Synonyms=SMP3;
DR   GO; GO:0000026; F:alpha-1,2-mannosyltransferase activity; IMP:UniProtKB.
DR   GO; GO:0000030; F:mannosyltransferase activity; IGI:UniProtKB.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0097502; P:mannosylation; IMP:GOC.
//
ID   PIHD2_HUMAN             Reviewed;         315 AA.
AC   Q8WWB5; B4DU48; E9PD82;
DE   RecName: Full=PIH1 domain-containing protein 2;
GN   Name=PIH1D2;
//
ID   PIHD3_HUMAN             Reviewed;         214 AA.
AC   Q9NQM4; D3DUX5; Q86WE1;
DE   RecName: Full=Protein PIH1D3;
DE   AltName: Full=PIH1 domain-containing protein 3;
DE   AltName: Full=Sarcoma antigen NY-SAR-97;
GN   Name=PIH1D3; Synonyms=CXorf41;
//
ID   PILRA_HUMAN             Reviewed;         303 AA.
AC   Q9UKJ1; Q8NHI1;
DE   RecName: Full=Paired immunoglobulin-like type 2 receptor alpha;
DE   AltName: Full=Cell surface receptor FDF03;
DE   AltName: Full=Inhibitory receptor PILR-alpha;
DE   Flags: Precursor;
GN   Name=PILRA;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007165; P:signal transduction; IDA:MGI.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PILRB_HUMAN             Reviewed;         227 AA.
AC   Q9UKJ0; Q69YF9; Q9HBS0;
DE   RecName: Full=Paired immunoglobulin-like type 2 receptor beta;
DE   AltName: Full=Activating receptor PILR-beta;
DE   AltName: Full=Cell surface receptor FDFACT;
DE   Flags: Precursor;
GN   Name=PILRB; Synonyms=FDFACT; ORFNames=PP1551;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:UniProtKB.
//
ID   PIM1_HUMAN              Reviewed;         404 AA.
AC   P11309; Q38RT9; Q5T7H7; Q96RG3;
DE   RecName: Full=Serine/threonine-protein kinase pim-1;
DE            EC=2.7.11.1;
GN   Name=PIM1;
DR   GuidetoPHARMACOLOGY; 2158; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030212; P:hyaluronan metabolic process; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   PIM2_HUMAN              Reviewed;         311 AA.
AC   Q9P1W9; A8K4G6; Q99739;
DE   RecName: Full=Serine/threonine-protein kinase pim-2;
DE            EC=2.7.11.1;
DE   AltName: Full=Pim-2h;
GN   Name=PIM2;
DR   GuidetoPHARMACOLOGY; 2159; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   PIM3_HUMAN              Reviewed;         326 AA.
AC   Q86V86; A5D8X8; A8K7J0; B1B0P0; Q68BM2;
DE   RecName: Full=Serine/threonine-protein kinase pim-3;
DE            EC=2.7.11.1;
GN   Name=PIM3;
DR   GuidetoPHARMACOLOGY; 2160; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016572; P:histone phosphorylation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
//
ID   PIMT_HUMAN              Reviewed;         227 AA.
AC   P22061; A8K109; J3KP72; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061;
AC   Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03;
DE   RecName: Full=Protein-L-isoaspartate(D-aspartate) O-methyltransferase;
DE            Short=PIMT;
DE            EC=2.1.1.77;
DE   AltName: Full=L-isoaspartyl protein carboxyl methyltransferase;
DE   AltName: Full=Protein L-isoaspartyl/D-aspartyl methyltransferase;
DE   AltName: Full=Protein-beta-aspartate methyltransferase;
GN   Name=PCMT1;
DR   GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0006479; P:protein methylation; TAS:ProtInc.
DR   GO; GO:0030091; P:protein repair; TAS:UniProtKB.
//
ID   PIN1_HUMAN              Reviewed;         163 AA.
AC   Q13526; A8K4V9; Q53X75;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1;
DE            EC=5.2.1.8;
DE   AltName: Full=Peptidyl-prolyl cis-trans isomerase Pin1;
DE            Short=PPIase Pin1;
DE   AltName: Full=Rotamase Pin1;
GN   Name=PIN1;
DR   GO; GO:0032794; F:GTPase activating protein binding; IPI:BHF-UCL.
DR   GO; GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:BHF-UCL.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.
DR   GO; GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.
DR   GO; GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:2000146; P:negative regulation of cell motility; IDA:BHF-UCL.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IGI:MGI.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IMP:BHF-UCL.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:GOC.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:MGI.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
DR   GO; GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
//
ID   PIN4_HUMAN              Reviewed;         131 AA.
AC   Q9Y237; A8E0G6; B3KXM0; F5H1P5; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6;
AC   Q6IRW4;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4;
DE            EC=5.2.1.8;
DE   AltName: Full=Parvulin-14;
DE            Short=Par14;
DE            Short=hPar14;
DE   AltName: Full=Parvulin-17;
DE            Short=Par17;
DE            Short=hPar17;
DE   AltName: Full=Peptidyl-prolyl cis-trans isomerase Pin4;
DE            Short=PPIase Pin4;
DE   AltName: Full=Peptidyl-prolyl cis/trans isomerase EPVH;
DE            Short=hEPVH;
DE   AltName: Full=Rotamase Pin4;
GN   Name=PIN4;
DR   GO; GO:0003681; F:bent DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
//
ID   PININ_HUMAN             Reviewed;         717 AA.
AC   Q9H307; B4DZX8; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9UHZ9;
AC   Q9UQR9;
DE   RecName: Full=Pinin;
DE   AltName: Full=140 kDa nuclear and cell adhesion-related phosphoprotein;
DE   AltName: Full=Desmosome-associated protein;
DE   AltName: Full=Domain-rich serine protein;
DE            Short=DRS protein;
DE            Short=DRSP;
DE   AltName: Full=Melanoma metastasis clone A protein;
DE   AltName: Full=Nuclear protein SDK3;
DE   AltName: Full=SR-like protein;
GN   Name=PNN; Synonyms=DRS, MEMA;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PINK1_HUMAN             Reviewed;         581 AA.
AC   Q9BXM7; Q8N6T9; Q8NBU3; Q96DE4;
DE   RecName: Full=Serine/threonine-protein kinase PINK1, mitochondrial;
DE            EC=2.7.11.1;
DE   AltName: Full=BRPK;
DE   AltName: Full=PTEN-induced putative kinase protein 1;
DE   Flags: Precursor;
GN   Name=PINK1;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0055131; F:C3HC4-type RING finger domain binding; IPI:BHF-UCL.
DR   GO; GO:0010857; F:calcium-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0016301; F:kinase activity; IDA:MGI.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0097237; P:cellular response to toxic substance; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0033603; P:positive regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IMP:BHF-UCL.
DR   GO; GO:0032226; P:positive regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0043254; P:regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
//
ID   PINL_HUMAN              Reviewed;         100 AA.
AC   O15428; B2RBW1; Q5VW75;
DE   RecName: Full=Putative PIN1-like protein;
DE   AltName: Full=Peptidylprolyl cis-trans isomerase NIMA-interacting 1 pseudogene 1;
GN   Name=PIN1P1; Synonyms=PIN1L;
//
ID   PINX1_HUMAN             Reviewed;         328 AA.
AC   Q96BK5; B2R9B1; Q548A5; Q6QWG9; Q7Z7J8; Q96QD7; Q9HBU7; Q9NWW2;
DE   RecName: Full=PIN2/TERF1-interacting telomerase inhibitor 1;
DE   AltName: Full=Liver-related putative tumor suppressor;
DE   AltName: Full=Pin2-interacting protein X1;
DE   AltName: Full=Protein 67-11-3;
DE   AltName: Full=TRF1-interacting protein 1;
GN   Name=PINX1; Synonyms=LPTL, LPTS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010521; F:telomerase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0070034; F:telomeric RNA binding; IDA:UniProtKB.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; TAS:GOC.
DR   GO; GO:0051972; P:regulation of telomerase activity; TAS:UniProtKB.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; IEA:Ensembl.
//
ID   PINLY_HUMAN             Reviewed;         204 AA.
AC   A6NC86; B7Z457; O95053;
DE   RecName: Full=phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein;
DE   Flags: Precursor;
GN   Name=PINLYP;
DR   GO; GO:0004859; F:phospholipase inhibitor activity; IEA:InterPro.
//
ID   PIPNA_HUMAN             Reviewed;         270 AA.
AC   Q00169;
DE   RecName: Full=Phosphatidylinositol transfer protein alpha isoform;
DE            Short=PI-TP-alpha;
DE            Short=PtdIns transfer protein alpha;
DE            Short=PtdInsTP alpha;
GN   Name=PITPNA; Synonyms=PITPN;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008525; F:phosphatidylcholine transporter activity; TAS:ProtInc.
DR   GO; GO:0008526; F:phosphatidylinositol transporter activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0015914; P:phospholipid transport; TAS:GOC.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PIPNB_HUMAN             Reviewed;         271 AA.
AC   P48739; B3KYB8; Q8N5W1;
DE   RecName: Full=Phosphatidylinositol transfer protein beta isoform;
DE            Short=PI-TP-beta;
DE            Short=PtdIns transfer protein beta;
DE            Short=PtdInsTP beta;
GN   Name=PITPNB;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0015914; P:phospholipid transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PIPSL_HUMAN             Reviewed;         862 AA.
AC   A2A3N6; Q6NUK8;
DE   RecName: Full=Putative PIP5K1A and PSMD4-like protein;
DE            Short=PIP5K1A-PSMD4;
GN   Name=PIPSL; Synonyms=PSMD4P2;
DR   GO; GO:0016307; F:phosphatidylinositol phosphate kinase activity; IEA:InterPro.
//
ID   PIP_HUMAN               Reviewed;         146 AA.
AC   P12273; A0A963; A0A9C3; A0A9F3; A4D2I1;
DE   RecName: Full=Prolactin-inducible protein;
DE   AltName: Full=Gross cystic disease fluid protein 15;
DE            Short=GCDFP-15;
DE   AltName: Full=Prolactin-induced protein;
DE   AltName: Full=Secretory actin-binding protein;
DE            Short=SABP;
DE   AltName: Full=gp17;
DE   Flags: Precursor;
GN   Name=PIP; Synonyms=GCDFP15, GPIP4;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IMP:UniProt.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProt.
DR   GO; GO:0019864; F:IgG binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProt.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0070233; P:negative regulation of T cell apoptotic process; IMP:UniProt.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProt.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProt.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   PIRT_HUMAN              Reviewed;         137 AA.
AC   P0C851; B7Z648;
DE   RecName: Full=Phosphoinositide-interacting protein;
GN   Name=PIRT;
//
ID   PIR_HUMAN               Reviewed;         290 AA.
AC   O00625; Q5U0G0; Q6FHD2;
DE   RecName: Full=Pirin;
DE            EC=1.13.11.24;
DE   AltName: Full=Probable quercetin 2,3-dioxygenase PIR;
DE            Short=Probable quercetinase;
GN   Name=PIR;
DR   GO; GO:0046872; F:metal ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008127; F:quercetin 2,3-dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IMP:UniProtKB.
DR   GO; GO:0030224; P:monocyte differentiation; IMP:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PISD_HUMAN              Reviewed;         409 AA.
AC   Q9UG56; B1AKM7; O43207; O95535; Q6IC28; Q96GQ2; Q9UGA9;
DE   RecName: Full=Phosphatidylserine decarboxylase proenzyme;
DE            EC=4.1.1.65;
DE   Contains:
DE     RecName: Full=Phosphatidylserine decarboxylase alpha chain;
DE   Contains:
DE     RecName: Full=Phosphatidylserine decarboxylase beta chain;
GN   Name=PISD;
DR   GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PIT1_HUMAN              Reviewed;         291 AA.
AC   P28069; O75757; Q15132; Q15133; Q9UD34; Q9UEL3;
DE   RecName: Full=Pituitary-specific positive transcription factor 1;
DE            Short=PIT-1;
DE   AltName: Full=Growth hormone factor 1;
DE            Short=GHF-1;
GN   Name=POU1F1; Synonyms=GHF1, PIT1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051169; P:nuclear transport; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032962; P:positive regulation of inositol trisphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0043567; P:regulation of insulin-like growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060133; P:somatotropin secreting cell development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PITC1_HUMAN             Reviewed;         332 AA.
AC   Q9UKF7; A8K473; J3QR20; Q96I07;
DE   RecName: Full=Cytoplasmic phosphatidylinositol transfer protein 1;
DE   AltName: Full=Mammalian rdgB homolog beta;
DE            Short=M-rdgB beta;
DE            Short=MrdgBbeta;
DE   AltName: Full=Retinal degeneration B homolog beta;
DE            Short=RdgBbeta;
GN   Name=PITPNC1;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008526; F:phosphatidylinositol transporter activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015914; P:phospholipid transport; IMP:GOC.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
//
ID   PITH1_HUMAN             Reviewed;         211 AA.
AC   Q9GZP4; B2R7J4; Q5QPN6; Q5QPN7; Q9NRI8;
DE   RecName: Full=PITH domain-containing protein 1;
GN   Name=PITHD1; Synonyms=C1orf128; ORFNames=AD039, HT014, PP603;
//
ID   PITM2_HUMAN             Reviewed;        1349 AA.
AC   Q9BZ72; Q9P271;
DE   RecName: Full=Membrane-associated phosphatidylinositol transfer protein 2;
DE   AltName: Full=Phosphatidylinositol transfer protein, membrane-associated 2;
DE            Short=PITPnm 2;
DE   AltName: Full=Pyk2 N-terminal domain-interacting receptor 3;
DE            Short=NIR-3;
GN   Name=PITPNM2; Synonyms=KIAA1457, NIR3;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; NAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   PITM3_HUMAN             Reviewed;         974 AA.
AC   Q9BZ71; A1A5D0; F8WEW5; Q59GH9; Q9NPQ4;
DE   RecName: Full=Membrane-associated phosphatidylinositol transfer protein 3;
DE   AltName: Full=Phosphatidylinositol transfer protein, membrane-associated 3;
DE            Short=PITPnm 3;
DE   AltName: Full=Pyk2 N-terminal domain-interacting receptor 1;
DE            Short=NIR-1;
GN   Name=PITPNM3; Synonyms=NIR1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008526; F:phosphatidylinositol transporter activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; TAS:UniProtKB.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; TAS:UniProtKB.
DR   GO; GO:0015914; P:phospholipid transport; TAS:GOC.
//
ID   PITM1_HUMAN             Reviewed;        1244 AA.
AC   O00562; A6NME4; Q6T7X3; Q8TBN3; Q9BZ73;
DE   RecName: Full=Membrane-associated phosphatidylinositol transfer protein 1;
DE   AltName: Full=Drosophila retinal degeneration B homolog;
DE   AltName: Full=Phosphatidylinositol transfer protein, membrane-associated 1;
DE            Short=PITPnm 1;
DE   AltName: Full=Pyk2 N-terminal domain-interacting receptor 2;
DE            Short=NIR-2;
GN   Name=PITPNM1; Synonyms=DRES9, NIR2, PITPNM;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008526; F:phosphatidylinositol transporter activity; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:ProtInc.
DR   GO; GO:0015914; P:phospholipid transport; TAS:GOC.
DR   GO; GO:0007602; P:phototransduction; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   PITX1_HUMAN             Reviewed;         314 AA.
AC   P78337; A8K3M0; D3DQB0; O14677; O60425; Q9BTI5;
DE   RecName: Full=Pituitary homeobox 1;
DE   AltName: Full=Hindlimb-expressed homeobox protein backfoot;
DE   AltName: Full=Homeobox protein PITX1;
DE   AltName: Full=Paired-like homeodomain transcription factor 1;
GN   Name=PITX1; Synonyms=BFT, PTX1;
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0014707; P:branchiomeric skeletal muscle development; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048625; P:myoblast fate commitment; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   PITX3_HUMAN             Reviewed;         302 AA.
AC   O75364; Q5VZL2;
DE   RecName: Full=Pituitary homeobox 3;
DE   AltName: Full=Homeobox protein PITX3;
DE   AltName: Full=Paired-like homeodomain transcription factor 3;
GN   Name=PITX3; Synonyms=PTX3;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0002088; P:lens development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; ISS:UniProtKB.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PITX2_HUMAN             Reviewed;         317 AA.
AC   Q99697; A8K6C6; B2RA02; B3KXS0; O60578; O60579; O60580; Q3KQX9;
AC   Q9BY17;
DE   RecName: Full=Pituitary homeobox 2;
DE   AltName: Full=ALL1-responsive protein ARP1;
DE   AltName: Full=Homeobox protein PITX2;
DE   AltName: Full=Paired-like homeodomain transcription factor 2;
DE   AltName: Full=RIEG bicoid-related homeobox transcription factor;
DE   AltName: Full=Solurshin;
GN   Name=PITX2; Synonyms=ARP1, RGS, RIEG, RIEG1;
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IC:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0008134; F:transcription factor binding; IPI:MGI.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0003171; P:atrioventricular valve development; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IMP:BHF-UCL.
DR   GO; GO:0003253; P:cardiac neural crest cell migration involved in outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0061325; P:cell proliferation involved in outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035993; P:deltoid tuberosity development; IMP:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0061031; P:endodermal digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0002074; P:extraocular skeletal muscle development; IEA:Ensembl.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0035315; P:hair cell differentiation; IC:BHF-UCL.
DR   GO; GO:0021855; P:hypothalamus cell migration; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0061072; P:iris morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060460; P:left lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0070986; P:left/right axis specification; ISS:BHF-UCL.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IMP:BHF-UCL.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:2000288; P:positive regulation of myoblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0060127; P:prolactin secreting cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0003350; P:pulmonary myocardium development; IEA:Ensembl.
DR   GO; GO:0060577; P:pulmonary vein morphogenesis; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0060126; P:somatotropin secreting cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0048536; P:spleen development; ISS:BHF-UCL.
DR   GO; GO:0021763; P:subthalamic nucleus development; IEA:Ensembl.
DR   GO; GO:0060578; P:superior vena cava morphogenesis; IEA:Ensembl.
DR   GO; GO:0035886; P:vascular smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0055015; P:ventricular cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:Ensembl.
//
ID   PIWL1_HUMAN             Reviewed;         861 AA.
AC   Q96J94; A4F266; O95404; Q8NA60; Q8TBY5; Q96JD5;
DE   RecName: Full=Piwi-like protein 1;
GN   Name=PIWIL1; Synonyms=HIWI;
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0034584; F:piRNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
//
ID   PIWL2_HUMAN             Reviewed;         973 AA.
AC   Q8TC59; A8K4S3; A8K8S5; B0AZN9; B0AZP2; B4DR22; E7ECA4; Q96SW6;
AC   Q9NW28;
DE   RecName: Full=Piwi-like protein 2;
DE   AltName: Full=Cancer/testis antigen 80;
DE            Short=CT80;
GN   Name=PIWIL2; Synonyms=HILI;
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0034584; F:piRNA binding; IDA:UniProtKB.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0030718; P:germ-line stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; ISS:UniProtKB.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0060903; P:positive regulation of meiosis I; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; ISS:UniProtKB.
DR   GO; GO:0000966; P:RNA 5'-end processing; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   PIWL4_HUMAN             Reviewed;         852 AA.
AC   Q7Z3Z4; B4DEG5; Q68CZ4; Q8N8G9; Q8N9V8; Q8NEH2;
DE   RecName: Full=Piwi-like protein 4;
GN   Name=PIWIL4; Synonyms=HIWI2, PIWI;
DR   GO; GO:0034584; F:piRNA binding; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   PIWL3_HUMAN             Reviewed;         882 AA.
AC   Q7Z3Z3;
DE   RecName: Full=Piwi-like protein 3;
GN   Name=PIWIL3;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   PJA1_HUMAN              Reviewed;         643 AA.
AC   Q8NG27; A2A322; Q5JUT8; Q5JUT9; Q8NG28; Q9HAC1;
DE   RecName: Full=E3 ubiquitin-protein ligase Praja-1;
DE            Short=Praja1;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 70;
GN   Name=PJA1; Synonyms=RNF70;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
//
ID   PJA2_HUMAN              Reviewed;         708 AA.
AC   O43164; A8K6U4; D3DSZ5; Q68D49; Q8N1G5;
DE   RecName: Full=E3 ubiquitin-protein ligase Praja-2;
DE            Short=Praja2;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 131;
GN   Name=PJA2; Synonyms=KIAA0438, RNF131;
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IMP:UniProtKB.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IMP:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007616; P:long-term memory; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010738; P:regulation of protein kinase A signaling; IMP:UniProtKB.
//
ID   PJVK_HUMAN              Reviewed;         352 AA.
AC   Q0ZLH3; A0PK14; B9EJE2;
DE   RecName: Full=Pejvakin;
DE   AltName: Full=Autosomal recessive deafness type 59 protein;
GN   Name=DFNB59; Synonyms=PJVK;
DR   GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
//
ID   PK1IP_HUMAN             Reviewed;         392 AA.
AC   Q9NWT1; Q5T4J2; Q96QJ8; Q96T87;
DE   RecName: Full=p21-activated protein kinase-interacting protein 1;
DE   AltName: Full=PAK/PLC-interacting protein 1;
DE            Short=hPIP1;
DE   AltName: Full=PAK1-interacting protein 1;
DE   AltName: Full=WD repeat-containing protein 84;
GN   Name=PAK1IP1; Synonyms=PIP1, WDR84;
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
//
ID   PK1L1_HUMAN             Reviewed;        2849 AA.
AC   Q8TDX9; Q6UWK1;
DE   RecName: Full=Polycystic kidney disease protein 1-like 1;
DE   AltName: Full=PC1-like 1 protein;
DE   AltName: Full=Polycystin-1L1;
GN   Name=PKD1L1; ORFNames=UNQ5785/PRO19563;
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome.
DR   GO; GO:0003127; P:detection of nodal flow; ISS:BHF-UCL.
DR   GO; GO:0070986; P:left/right axis specification; ISS:BHF-UCL.
//
ID   PK1L2_HUMAN             Reviewed;        2459 AA.
AC   Q7Z442; Q6UEE1; Q6ZN46; Q6ZSP2; Q8N1H9; Q96CL2; Q96Q08;
DE   RecName: Full=Polycystic kidney disease protein 1-like 2;
DE   AltName: Full=PC1-like 2 protein;
DE   AltName: Full=Polycystin-1L2;
DE   Flags: Precursor;
GN   Name=PKD1L2; Synonyms=KIAA1879, PC1L2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005261; F:cation channel activity; IEA:Ensembl.
DR   GO; GO:0033040; F:sour taste receptor activity; IEA:Ensembl.
DR   GO; GO:0071468; P:cellular response to acidity; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   PK1L3_HUMAN             Reviewed;        1732 AA.
AC   Q7Z443;
DE   RecName: Full=Polycystic kidney disease protein 1-like 3;
DE   AltName: Full=PC1-like 3 protein;
DE   AltName: Full=Polycystin-1L3;
DE   Flags: Precursor;
GN   Name=PKD1L3;
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006812; P:cation transport; ISS:BHF-UCL.
DR   GO; GO:0071468; P:cellular response to acidity; ISS:BHF-UCL.
DR   GO; GO:0001581; P:detection of chemical stimulus involved in sensory perception of sour taste; ISS:BHF-UCL.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0050915; P:sensory perception of sour taste; IMP:UniProt.
//
ID   PK2L1_HUMAN             Reviewed;         805 AA.
AC   Q9P0L9; O75972; Q5W039; Q9UP35; Q9UPA2;
DE   RecName: Full=Polycystic kidney disease 2-like 1 protein;
DE   AltName: Full=Polycystin-2 homolog;
DE   AltName: Full=Polycystin-2L1;
DE   AltName: Full=Polycystin-L;
DE   AltName: Full=Polycystin-L1;
GN   Name=PKD2L1; Synonyms=PKD2L, PKDL, TRPP3;
DR   GuidetoPHARMACOLOGY; 505; -.
DR   GO; GO:0051393; F:alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IDA:BHF-UCL.
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; IDA:BHF-UCL.
DR   GO; GO:0005261; F:cation channel activity; IDA:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005272; F:sodium channel activity; IDA:BHF-UCL.
DR   GO; GO:0033040; F:sour taste receptor activity; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; ISS:BHF-UCL.
DR   GO; GO:0071468; P:cellular response to acidity; ISS:BHF-UCL.
DR   GO; GO:0001581; P:detection of chemical stimulus involved in sensory perception of sour taste; ISS:BHF-UCL.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0070207; P:protein homotrimerization; IDA:UniProtKB.
DR   GO; GO:0050915; P:sensory perception of sour taste; IMP:UniProt.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
//
ID   PK2L2_HUMAN             Reviewed;         624 AA.
AC   Q9NZM6; A6NK98; B4DXD2; E9PC91; E9PDG4; Q86YB4; Q9UNJ0;
DE   RecName: Full=Polycystic kidney disease 2-like 2 protein;
DE   AltName: Full=Polycystin-2L2;
DE   AltName: Full=Polycystin-L2;
GN   Name=PKD2L2;
DR   GO; GO:0005262; F:calcium channel activity; IBA:RefGenome.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GOC.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome.
//
ID   PK3C3_HUMAN             Reviewed;         887 AA.
AC   Q8NEB9; Q15134;
DE   RecName: Full=Phosphatidylinositol 3-kinase catalytic subunit type 3;
DE            Short=PI3-kinase type 3;
DE            Short=PI3K type 3;
DE            Short=PtdIns-3-kinase type 3;
DE            EC=2.7.1.137;
DE   AltName: Full=Phosphatidylinositol 3-kinase p100 subunit;
DE   AltName: Full=Phosphoinositide-3-kinase class 3;
DE   AltName: Full=hVps34;
GN   Name=PIK3C3; Synonyms=VPS34;
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; IMP:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:0050708; P:regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0043201; P:response to leucine; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   PK3CA_HUMAN             Reviewed;        1068 AA.
AC   P42336; Q14CW1; Q99762;
DE   RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform;
DE            Short=PI3-kinase subunit alpha;
DE            Short=PI3K-alpha;
DE            Short=PI3Kalpha;
DE            Short=PtdIns-3-kinase subunit alpha;
DE            EC=2.7.1.153;
DE   AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;
DE            Short=PtdIns-3-kinase subunit p110-alpha;
DE            Short=p110alpha;
DE   AltName: Full=Phosphoinositide-3-kinase catalytic alpha polypeptide;
DE   AltName: Full=Serine/threonine protein kinase PIK3CA;
DE            EC=2.7.11.1;
GN   Name=PIK3CA;
DR   GuidetoPHARMACOLOGY; 2153; -.
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IDA:UniProtKB.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; TAS:Reactome.
DR   GO; GO:0035004; F:phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IEA:Ensembl.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060048; P:cardiac muscle contraction; TAS:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; TAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0044029; P:hypomethylation of CpG island; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038028; P:insulin receptor signaling pathway via phosphatidylinositol 3-kinase; TAS:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; IDA:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:2000653; P:regulation of genetic imprinting; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001944; P:vasculature development; TAS:UniProtKB.
//
ID   PK3CB_HUMAN             Reviewed;        1070 AA.
AC   P42338; D3DNF0; Q24JU2;
DE   RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform;
DE            Short=PI3-kinase subunit beta;
DE            Short=PI3K-beta;
DE            Short=PI3Kbeta;
DE            Short=PtdIns-3-kinase subunit beta;
DE            EC=2.7.1.153;
DE   AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta;
DE            Short=PtdIns-3-kinase subunit p110-beta;
DE            Short=p110beta;
GN   Name=PIK3CB; Synonyms=PIK3C1;
DR   GuidetoPHARMACOLOGY; 2154; -.
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IBA:RefGenome.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035004; F:phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; TAS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0040016; P:embryonic cleavage; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; TAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; TAS:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; TAS:UniProtKB.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:2000369; P:regulation of clathrin-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:UniProtKB.
//
ID   PK3CD_HUMAN             Reviewed;        1044 AA.
AC   O00329; A6NCG0; G1FFP1; O15445; Q5SR49;
DE   RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform;
DE            Short=PI3-kinase subunit delta;
DE            Short=PI3K-delta;
DE            Short=PI3Kdelta;
DE            Short=PtdIns-3-kinase subunit delta;
DE            EC=2.7.1.153;
DE   AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta;
DE            Short=PtdIns-3-kinase subunit p110-delta;
DE            Short=p110delta;
GN   Name=PIK3CD;
DR   GuidetoPHARMACOLOGY; 2155; -.
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035004; F:phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002250; P:adaptive immune response; TAS:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0035754; P:B cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0001816; P:cytokine production; TAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0002551; P:mast cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0043303; P:mast cell degranulation; TAS:UniProtKB.
DR   GO; GO:0060374; P:mast cell differentiation; TAS:UniProtKB.
DR   GO; GO:0030101; P:natural killer cell activation; TAS:UniProtKB.
DR   GO; GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0001779; P:natural killer cell differentiation; TAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.
DR   GO; GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; TAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0036092; P:phosphatidylinositol-3-phosphate biosynthetic process; NAS:GOC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; TAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:UniProtKB.
//
ID   PK3CG_HUMAN             Reviewed;        1102 AA.
AC   P48736; A4D0Q6; Q8IV23; Q9BZC8;
DE   RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform;
DE            Short=PI3-kinase subunit gamma;
DE            Short=PI3K-gamma;
DE            Short=PI3Kgamma;
DE            Short=PtdIns-3-kinase subunit gamma;
DE            EC=2.7.1.153;
DE   AltName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma;
DE            Short=PtdIns-3-kinase subunit p110-gamma;
DE            Short=p110gamma;
DE   AltName: Full=Phosphoinositide-3-kinase catalytic gamma polypeptide;
DE   AltName: Full=Serine/threonine protein kinase PIK3CG;
DE            EC=2.7.11.1;
DE   AltName: Full=p120-PI3K;
GN   Name=PIK3CG;
DR   GuidetoPHARMACOLOGY; 2156; -.
DR   GO; GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IBA:RefGenome.
DR   GO; GO:0035005; F:1-phosphatidylinositol-4-phosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0035004; F:phosphatidylinositol 3-kinase activity; TAS:UniProtKB.
DR   GO; GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001816; P:cytokine production; TAS:UniProtKB.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0043303; P:mast cell degranulation; TAS:UniProtKB.
DR   GO; GO:0035747; P:natural killer cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0055118; P:negative regulation of cardiac muscle contraction; TAS:UniProtKB.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IEA:Ensembl.
DR   GO; GO:0010897; P:negative regulation of triglyceride catabolic process; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.
DR   GO; GO:0072672; P:neutrophil extravasation; TAS:UniProtKB.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; TAS:UniProtKB.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; TAS:UniProtKB.
DR   GO; GO:0002679; P:respiratory burst involved in defense response; TAS:UniProtKB.
DR   GO; GO:0032252; P:secretory granule localization; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0010818; P:T cell chemotaxis; TAS:UniProtKB.
DR   GO; GO:0042098; P:T cell proliferation; TAS:UniProtKB.
//
ID   PKCB1_HUMAN             Reviewed;        1186 AA.
AC   Q9ULU4; B3KVL2; B7Z2A8; B7Z3E0; B7Z680; B7ZM62; E1P5U5; F5H0X3;
AC   H7C0U2; J3KPU3; Q13517; Q2HXV1; Q2HXV2; Q2HXV3; Q2HXV4; Q2HXV7;
AC   Q2HXV8; Q2HXV9; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; Q5TH09;
AC   Q5TH11; Q6MZM1; Q8WXC5; Q9H1F3; Q9H1F4; Q9H1F5; Q9H1L8; Q9H1L9;
AC   Q9H2G5; Q9NYN3; Q9UIX6;
DE   RecName: Full=Protein kinase C-binding protein 1;
DE   AltName: Full=Cutaneous T-cell lymphoma-associated antigen se14-3;
DE            Short=CTCL-associated antigen se14-3;
DE   AltName: Full=Rack7;
DE   AltName: Full=Zinc finger MYND domain-containing protein 8;
GN   Name=ZMYND8; Synonyms=KIAA1125, PRKCBP1, RACK7;
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070491; F:repressing transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:GOC.
//
ID   PKD1_HUMAN              Reviewed;        4303 AA.
AC   P98161; Q15140; Q15141;
DE   RecName: Full=Polycystin-1;
DE   AltName: Full=Autosomal dominant polycystic kidney disease 1 protein;
DE   Flags: Precursor;
GN   Name=PKD1;
DR   GO; GO:0005262; F:calcium channel activity; IBA:RefGenome.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005261; F:cation channel activity; ISS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GOC.
DR   GO; GO:0007161; P:calcium-independent cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEP:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; ISS:BHF-UCL.
DR   GO; GO:0050982; P:detection of mechanical stimulus; ISS:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; IEP:UniProtKB.
DR   GO; GO:0001892; P:embryonic placenta development; ISS:BHF-UCL.
DR   GO; GO:0048806; P:genitalia development; IEP:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEP:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; ISS:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; ISS:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0060428; P:lung epithelium development; IEP:UniProtKB.
DR   GO; GO:0072177; P:mesonephric duct development; IEP:UniProtKB.
DR   GO; GO:0072164; P:mesonephric tubule development; IEP:UniProtKB.
DR   GO; GO:0072218; P:metanephric ascending thin limb development; IEP:UniProtKB.
DR   GO; GO:0072205; P:metanephric collecting duct development; IEP:UniProtKB.
DR   GO; GO:0072287; P:metanephric distal tubule morphogenesis; IEP:UniProtKB.
DR   GO; GO:0072237; P:metanephric proximal tubule development; IEP:UniProtKB.
DR   GO; GO:0021915; P:neural tube development; IEP:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0060674; P:placenta blood vessel development; ISS:BHF-UCL.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006611; P:protein export from nucleus; ISS:BHF-UCL.
DR   GO; GO:0060236; P:regulation of mitotic spindle organization; IEA:Ensembl.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.
DR   GO; GO:0043588; P:skin development; IEP:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; IEP:UniProtKB.
//
ID   PKDCC_HUMAN             Reviewed;         493 AA.
AC   Q504Y2; D6W5A0; Q96I09;
DE   RecName: Full=Protein kinase domain-containing protein, cytoplasmic;
DE            EC=2.7.-.-;
DE   AltName: Full=Protein kinase-like protein SgK493;
DE   AltName: Full=Sugen kinase 493;
DE   AltName: Full=Vertebrate lonesome kinase;
GN   Name=PKDCC; Synonyms=SGK493, VLK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048566; P:embryonic digestive tract development; ISS:UniProtKB.
DR   GO; GO:0048286; P:lung alveolus development; ISS:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0042997; P:negative regulation of Golgi to plasma membrane protein transport; ISS:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   PKDRE_HUMAN             Reviewed;        2253 AA.
AC   Q9NTG1; B1AJY3; O95850;
DE   RecName: Full=Polycystic kidney disease and receptor for egg jelly-related protein;
DE   AltName: Full=PKD and REJ homolog;
DE   Flags: Precursor;
GN   Name=PKDREJ;
DR   GO; GO:0005262; F:calcium channel activity; IBA:RefGenome.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007340; P:acrosome reaction; TAS:ProtInc.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GOC.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
DR   GO; GO:0060046; P:regulation of acrosome reaction; IEA:Ensembl.
//
ID   PKD2_HUMAN              Reviewed;         968 AA.
AC   Q13563; O60441; Q15764; Q2M1Q3; Q2M1Q5;
DE   RecName: Full=Polycystin-2;
DE   AltName: Full=Autosomal dominant polycystic kidney disease type II protein;
DE   AltName: Full=Polycystic kidney disease 2 protein;
DE   AltName: Full=Polycystwin;
DE   AltName: Full=R48321;
GN   Name=PKD2;
DR   GuidetoPHARMACOLOGY; 504; -.
DR   GO; GO:0042805; F:actinin binding; IDA:BHF-UCL.
DR   GO; GO:0051117; F:ATPase binding; ISS:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; ISS:BHF-UCL.
DR   GO; GO:0048763; F:calcium-induced calcium release activity; IDA:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL.
DR   GO; GO:0043398; F:HLH domain binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProt.
DR   GO; GO:0005267; F:potassium channel activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IDA:BHF-UCL.
DR   GO; GO:0022843; F:voltage-gated cation channel activity; IDA:BHF-UCL.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IDA:BHF-UCL.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IDA:BHF-UCL.
DR   GO; GO:0035904; P:aorta development; IEP:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEP:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; ISS:BHF-UCL.
DR   GO; GO:0071498; P:cellular response to fluid shear stress; IMP:BHF-UCL.
DR   GO; GO:0071464; P:cellular response to hydrostatic pressure; IDA:BHF-UCL.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IDA:BHF-UCL.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; NAS:BHF-UCL.
DR   GO; GO:0051298; P:centrosome duplication; NAS:BHF-UCL.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IMP:BHF-UCL.
DR   GO; GO:0050982; P:detection of mechanical stimulus; ISS:BHF-UCL.
DR   GO; GO:0003127; P:detection of nodal flow; ISS:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0071910; P:determination of liver left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0001892; P:embryonic placenta development; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; IEP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; ISS:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEP:UniProtKB.
DR   GO; GO:0072177; P:mesonephric duct development; IEP:UniProtKB.
DR   GO; GO:0072164; P:mesonephric tubule development; IEP:UniProtKB.
DR   GO; GO:0072218; P:metanephric ascending thin limb development; IEP:UniProtKB.
DR   GO; GO:0072214; P:metanephric cortex development; IEP:UniProtKB.
DR   GO; GO:0072219; P:metanephric cortical collecting duct development; IEP:UniProtKB.
DR   GO; GO:0072235; P:metanephric distal tubule development; IEP:UniProtKB.
DR   GO; GO:0072075; P:metanephric mesenchyme development; IEP:UniProtKB.
DR   GO; GO:0035502; P:metanephric part of ureteric bud development; IEP:UniProtKB.
DR   GO; GO:0072284; P:metanephric S-shaped body morphogenesis; IEP:UniProtKB.
DR   GO; GO:0072208; P:metanephric smooth muscle tissue development; IEP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:BHF-UCL.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL.
DR   GO; GO:0021915; P:neural tube development; IEP:UniProtKB.
DR   GO; GO:0060674; P:placenta blood vessel development; ISS:BHF-UCL.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0031587; P:positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IMP:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0090279; P:regulation of calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0030814; P:regulation of cAMP metabolic process; ISS:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0061441; P:renal artery morphogenesis; IEP:UniProtKB.
DR   GO; GO:0061333; P:renal tubule morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0021510; P:spinal cord development; IEP:UniProtKB.
//
ID   PKH4B_HUMAN             Reviewed;        1271 AA.
AC   Q96PX9;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 4B;
DE            Short=PH domain-containing family G member 4B;
GN   Name=PLEKHG4B; Synonyms=KIAA1909;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   PKHA1_HUMAN             Reviewed;         404 AA.
AC   Q9HB21; B3KQ55; D3DRE2; Q9BVK0;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 1;
DE            Short=PH domain-containing family A member 1;
DE   AltName: Full=Tandem PH domain-containing protein 1;
DE            Short=TAPP-1;
GN   Name=PLEKHA1; Synonyms=TAPP1;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IDA:UniProtKB.
DR   GO; GO:0008210; P:estrogen metabolic process; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0001553; P:luteinization; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0031529; P:ruffle organization; IDA:UniProtKB.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PKHA2_HUMAN             Reviewed;         425 AA.
AC   Q9HB19;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 2;
DE            Short=PH domain-containing family A member 2;
DE   AltName: Full=Tandem PH domain-containing protein 2;
DE            Short=TAPP-2;
GN   Name=PLEKHA2; Synonyms=TAPP2;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0001968; F:fibronectin binding; IMP:UniProtKB.
DR   GO; GO:0043236; F:laminin binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:UniProtKB.
//
ID   PKHA3_HUMAN             Reviewed;         300 AA.
AC   Q9HB20; Q4ZG69; Q86TQ1; Q9NXT3;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 3;
DE            Short=PH domain-containing family A member 3;
DE   AltName: Full=Phosphatidylinositol-four-phosphate adapter protein 1;
DE            Short=FAPP-1;
DE            Short=Phosphoinositol 4-phosphate adapter protein 1;
GN   Name=PLEKHA3; Synonyms=FAPP1;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
//
ID   PKHA4_HUMAN             Reviewed;         779 AA.
AC   Q9H4M7; Q8N4M8; Q8N658;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 4;
DE            Short=PH domain-containing family A member 4;
DE   AltName: Full=Phosphoinositol 3-phosphate-binding protein 1;
DE            Short=PEPP-1;
GN   Name=PLEKHA4; Synonyms=PEPP1;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.
//
ID   PKHA5_HUMAN             Reviewed;        1116 AA.
AC   Q9HAU0; A0JP03; B4DGS1; E9PHQ3; F5H0I0; Q6NSF8; Q86ST7; Q8N3K6;
AC   Q96DY9; Q9BVR4; Q9C0H7; Q9H924; Q9NVK8;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 5;
DE            Short=PH domain-containing family A member 5;
DE   AltName: Full=Phosphoinositol 3-phosphate-binding protein 2;
DE            Short=PEPP-2;
GN   Name=PLEKHA5; Synonyms=KIAA1686, PEPP2;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PKHA6_HUMAN             Reviewed;        1048 AA.
AC   Q9Y2H5; A7MD51; Q5VTI6;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 6;
DE            Short=PH domain-containing family A member 6;
DE   AltName: Full=Phosphoinositol 3-phosphate-binding protein 3;
DE            Short=PEPP-3;
GN   Name=PLEKHA6; Synonyms=KIAA0969, PEPP3;
//
ID   PKHA8_HUMAN             Reviewed;         519 AA.
AC   Q96JA3; B4DH00; Q7Z5V8; Q9BU78; Q9H274; Q9H8Z7;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 8;
DE            Short=PH domain-containing family A member 8;
DE   AltName: Full=Phosphatidylinositol-four-phosphate adapter protein 2;
DE            Short=FAPP-2;
DE            Short=Phosphoinositol 4-phosphate adapter protein 2;
DE            Short=hFAPP2;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-86;
GN   Name=PLEKHA8; Synonyms=FAPP2;
DR   GO; GO:0097001; F:ceramide binding; IDA:UniProtKB.
DR   GO; GO:0051861; F:glycolipid binding; IDA:UniProtKB.
DR   GO; GO:0017089; F:glycolipid transporter activity; IDA:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0035621; P:ER to Golgi ceramide transport; IDA:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   PKHA9_HUMAN             Reviewed;         391 AA.
AC   O95397;
DE   RecName: Full=Putative protein PLEKHA9;
DE   AltName: Full=Pleckstrin homology domain-containing family A member 8 pseudogene 1;
GN   Name=PLEKHA8P1; Synonyms=PLEKHA9; ORFNames=HAW1053;
DR   GO; GO:0051861; F:glycolipid binding; IEA:InterPro.
DR   GO; GO:0017089; F:glycolipid transporter activity; IEA:InterPro.
//
ID   PKHA7_HUMAN             Reviewed;        1121 AA.
AC   Q6IQ23; B4DK33; B4DWC3; Q86VZ7;
DE   RecName: Full=Pleckstrin homology domain-containing family A member 7;
DE            Short=PH domain-containing family A member 7;
GN   Name=PLEKHA7;
DR   GO; GO:0070097; F:delta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB.
//
ID   PKHB1_HUMAN             Reviewed;         243 AA.
AC   Q9UF11; A8K0Q5; B2RBP1; B7Z716; Q9UBF5; Q9UI37; Q9UI44;
DE   RecName: Full=Pleckstrin homology domain-containing family B member 1;
DE            Short=PH domain-containing family B member 1;
DE   AltName: Full=Evectin-1;
DE   AltName: Full=PH domain-containing protein in retina 1;
DE            Short=PHRET1;
DE   AltName: Full=Pleckstrin homology domain retinal protein 1;
GN   Name=PLEKHB1; Synonyms=EVT1, KPL1, PHR1, PHRET1;
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; NAS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; IEA:Ensembl.
//
ID   PKHD1_HUMAN             Reviewed;        4074 AA.
AC   P08F94; Q5VUA2; Q5VUA3; Q5VWV1; Q86Z26; Q8TCZ9;
DE   RecName: Full=Fibrocystin;
DE   AltName: Full=Polycystic kidney and hepatic disease 1 protein;
DE   AltName: Full=Polyductin;
DE   AltName: Full=Tigmin;
DE   Flags: Precursor;
GN   Name=PKHD1; Synonyms=FCYT, TIGM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProt.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProt.
DR   GO; GO:0051271; P:negative regulation of cellular component movement; ISS:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProt.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProt.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProt.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IMP:UniProt.
DR   GO; GO:0032006; P:regulation of TOR signaling; IMP:UniProt.
//
ID   PKHB2_HUMAN             Reviewed;         222 AA.
AC   Q96CS7; B4DF08; B4DZ66; B8ZZN1; Q53FF1; Q53TH7; Q86W37; Q9BV75;
AC   Q9NWK1;
DE   RecName: Full=Pleckstrin homology domain-containing family B member 2;
DE            Short=PH domain-containing family B member 2;
DE   AltName: Full=Evectin-2;
GN   Name=PLEKHB2; Synonyms=EVT2;
//
ID   PKHF1_HUMAN             Reviewed;         279 AA.
AC   Q96S99; Q96K11; Q9BUB9;
DE   RecName: Full=Pleckstrin homology domain-containing family F member 1;
DE            Short=PH domain-containing family F member 1;
DE   AltName: Full=Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains;
DE            Short=Apoptosis-inducing protein;
DE   AltName: Full=PH and FYVE domain-containing protein 1;
DE   AltName: Full=Phafin-1;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 15;
GN   Name=PLEKHF1; Synonyms=APPD, LAPF, ZFYVE15;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:BHF-UCL.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:BHF-UCL.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007032; P:endosome organization; IMP:BHF-UCL.
DR   GO; GO:0010508; P:positive regulation of autophagy; IDA:BHF-UCL.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0016050; P:vesicle organization; IMP:BHF-UCL.
//
ID   PKHF2_HUMAN             Reviewed;         249 AA.
AC   Q9H8W4;
DE   RecName: Full=Pleckstrin homology domain-containing family F member 2;
DE            Short=PH domain-containing family F member 2;
DE   AltName: Full=Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains;
DE            Short=EAPF;
DE   AltName: Full=PH and FYVE domain-containing protein 2;
DE   AltName: Full=Phafin-2;
DE            Short=Phafin2;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 18;
GN   Name=PLEKHF2; Synonyms=ZFYVE18;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   PKHG1_HUMAN             Reviewed;        1385 AA.
AC   Q9ULL1; Q5T1F2;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 1;
GN   Name=PLEKHG1; Synonyms=KIAA1209;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   PKHG3_HUMAN             Reviewed;        1219 AA.
AC   A1L390; A1L389; B5MEC9; O60339; Q6GMS3; Q6P4B1; Q7L3S3; Q86SW7;
AC   Q8TEF5; Q96EW6; Q9BT82;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 3;
DE            Short=PH domain-containing family G member 3;
GN   Name=PLEKHG3; Synonyms=KIAA0599;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   PKHG2_HUMAN             Reviewed;        1386 AA.
AC   Q9H7P9; B8ZZK6; C9J0Y4; Q6DHV6; Q96BU2; Q96D18; Q9H699;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 2;
DE            Short=PH domain-containing family G member 2;
GN   Name=PLEKHG2;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   PKHG4_HUMAN             Reviewed;        1191 AA.
AC   Q58EX7; Q4G0J8; Q4H485; Q56A69; Q9H7K4; Q9UFW0;
DE   RecName: Full=Puratrophin-1;
DE   AltName: Full=Pleckstrin homology domain-containing family G member 4;
DE            Short=PH domain-containing family G member 4;
DE   AltName: Full=Purkinje cell atrophy-associated protein 1;
GN   Name=PLEKHG4; Synonyms=PRTPHN1;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   PKHG5_HUMAN             Reviewed;        1062 AA.
AC   O94827; B3KU07; B7Z2M3; B7Z5X2; F5GZ21; F5H1I0; Q5SY17; Q5T8W5;
AC   Q5T8W9; Q6ZNM0; Q7Z436; Q86YD8; Q96BS1;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 5;
DE            Short=PH domain-containing family G member 5;
DE   AltName: Full=Guanine nucleotide exchange factor 720;
DE            Short=GEF720;
GN   Name=PLEKHG5; Synonyms=KIAA0720;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   PKHG6_HUMAN             Reviewed;         790 AA.
AC   Q3KR16; Q3SWR1; Q8N1P1; Q8WYY1; Q9H8F4; Q9NVK9;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 6;
DE            Short=PH domain-containing family G member 6;
DE   AltName: Full=Myosin-interacting guanine nucleotide exchange factor;
DE            Short=MyoGEF;
GN   Name=PLEKHG6;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   PKHH1_HUMAN             Reviewed;        1364 AA.
AC   Q9ULM0; A6H8X6; Q6PJL4; Q6ZWC7;
DE   RecName: Full=Pleckstrin homology domain-containing family H member 1;
DE            Short=PH domain-containing family H member 1;
GN   Name=PLEKHH1; Synonyms=KIAA1200;
//
ID   PKHG7_HUMAN             Reviewed;         379 AA.
AC   Q6ZR37; B2RNR7;
DE   RecName: Full=Pleckstrin homology domain-containing family G member 7;
DE            Short=PH domain-containing family G member 7;
GN   Name=PLEKHG7;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
//
ID   PKHH2_HUMAN             Reviewed;        1493 AA.
AC   Q8IVE3; Q5JPJ6; Q6P4Q1; Q8N3Q3;
DE   RecName: Full=Pleckstrin homology domain-containing family H member 2;
GN   Name=PLEKHH2; Synonyms=KIAA2028;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0030835; P:negative regulation of actin filament depolymerization; ISS:UniProtKB.
//
ID   PKHH3_HUMAN             Reviewed;         793 AA.
AC   Q7Z736; C9JQ76; Q59H20; Q96B28; Q9H7D6; Q9NT18;
DE   RecName: Full=Pleckstrin homology domain-containing family H member 3;
DE            Short=PH domain-containing family H member 3;
DE   Flags: Precursor;
GN   Name=PLEKHH3;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PKHJ1_HUMAN             Reviewed;         149 AA.
AC   Q9NW61; B3KUQ9; D6W604;
DE   RecName: Full=Pleckstrin homology domain-containing family J member 1;
DE            Short=PH domain-containing family J member 1;
DE   AltName: Full=Guanine nucleotide-releasing protein x;
GN   Name=PLEKHJ1; Synonyms=GNRPX;
//
ID   PKHL1_HUMAN             Reviewed;        4243 AA.
AC   Q86WI1; Q567P2; Q9UF27;
DE   RecName: Full=Fibrocystin-L;
DE   AltName: Full=Polycystic kidney and hepatic disease 1-like protein 1;
DE            Short=PKHD1-like protein 1;
DE   Flags: Precursor;
GN   Name=PKHD1L1;
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   PKHM1_HUMAN             Reviewed;        1056 AA.
AC   Q9Y4G2; Q6P2R5; Q8TEL9; Q9NPP5; Q9NYA0;
DE   RecName: Full=Pleckstrin homology domain-containing family M member 1;
DE            Short=PH domain-containing family M member 1;
DE   AltName: Full=162 kDa adapter protein;
DE            Short=AP162;
GN   Name=PLEKHM1; Synonyms=KIAA0356;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   PKHM2_HUMAN             Reviewed;        1019 AA.
AC   Q8IWE5; O94928; Q5VT65; Q6NUH9; Q7L8G1; Q8IVT7; Q8N2T4; Q96AY0;
AC   Q9NTF7;
DE   RecName: Full=Pleckstrin homology domain-containing family M member 2;
DE            Short=PH domain-containing family M member 2;
DE   AltName: Full=Salmonella-induced filaments A and kinesin-interacting protein;
DE            Short=SifA and kinesin-interacting protein;
GN   Name=PLEKHM2; Synonyms=KIAA0842, SKIP;
DR   GO; GO:0019894; F:kinesin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
//
ID   PKHM3_HUMAN             Reviewed;         761 AA.
AC   Q6ZWE6; B9EKV2; Q8WW68;
DE   RecName: Full=Pleckstrin homology domain-containing family M member 3;
DE            Short=PH domain-containing family M member 3;
GN   Name=PLEKHM3; Synonyms=PLEKHM1L;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   PKHMP_HUMAN             Reviewed;         520 AA.
AC   Q69YJ1;
DE   RecName: Full=Putative pleckstrin homology domain-containing family M member 1P;
GN   Name=PLEKHM1P;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   PKHN1_HUMAN             Reviewed;         663 AA.
AC   Q494U1; Q494U2; Q5SV98; Q9H0M7;
DE   RecName: Full=Pleckstrin homology domain-containing family N member 1;
DE            Short=PH domain-containing family N member 1;
GN   Name=PLEKHN1;
//
ID   PKHO1_HUMAN             Reviewed;         409 AA.
AC   Q53GL0; Q336K5; Q8IZ51; Q9NRV3; Q9UL48;
DE   RecName: Full=Pleckstrin homology domain-containing family O member 1;
DE            Short=PH domain-containing family O member 1;
DE   AltName: Full=C-Jun-binding protein;
DE            Short=JBP;
DE   AltName: Full=Casein kinase 2-interacting protein 1;
DE            Short=CK2-interacting protein 1;
DE            Short=CKIP-1;
DE   AltName: Full=Osteoclast maturation-associated gene 120 protein;
GN   Name=PLEKHO1; Synonyms=CKIP1, OC120; ORFNames=HQ0024c;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PKHS1_HUMAN             Reviewed;         462 AA.
AC   Q5SXH7; A8KA02; B3KX00; B6EDE1; Q5SXH8; Q5SXI0; Q6ZQR5; Q8NE42;
AC   Q9H5D9;
DE   RecName: Full=Pleckstrin homology domain-containing family S member 1;
DE            Short=PH domain-containing family S member 1;
DE   AltName: Full=Epididymis luminal protein 185;
DE            Short=hEL185;
GN   Name=PLEKHS1; Synonyms=C10orf81;
//
ID   PKHO2_HUMAN             Reviewed;         490 AA.
AC   Q8TD55; Q7L4H4; Q8WYS8;
DE   RecName: Full=Pleckstrin homology domain-containing family O member 2;
DE            Short=PH domain-containing family O member 2;
DE   AltName: Full=Pleckstrin homology domain-containing family Q member 1;
DE            Short=PH domain-containing family Q member 1;
GN   Name=PLEKHO2; Synonyms=PLEKHQ1; ORFNames=PP9099;
//
ID   PKN1_HUMAN              Reviewed;         942 AA.
AC   Q16512; A8K7W5; B2R9R4; B3KVN3; Q15143; Q504U4; Q8IUV5; Q9UD44;
DE   RecName: Full=Serine/threonine-protein kinase N1;
DE            EC=2.7.11.13;
DE   AltName: Full=Protease-activated kinase 1;
DE            Short=PAK-1;
DE   AltName: Full=Protein kinase C-like 1;
DE   AltName: Full=Protein kinase C-like PKN;
DE   AltName: Full=Protein kinase PKN-alpha;
DE   AltName: Full=Protein-kinase C-related kinase 1;
DE   AltName: Full=Serine-threonine protein kinase N;
GN   Name=PKN1; Synonyms=PAK1, PKN, PRK1, PRKCL1;
DR   GuidetoPHARMACOLOGY; 1520; -.
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0017049; F:GTP-Rho binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0035402; F:histone kinase activity (H3-T11 specific); IDA:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.
DR   GO; GO:0010631; P:epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0035407; P:histone H3-T11 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; IMP:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PKN2_HUMAN              Reviewed;         984 AA.
AC   Q16513; B4DQ21; B4DTP5; B4DVG1; D3DT24; Q08AF4; Q9H1W4;
DE   RecName: Full=Serine/threonine-protein kinase N2;
DE            EC=2.7.11.13;
DE   AltName: Full=PKN gamma;
DE   AltName: Full=Protein kinase C-like 2;
DE   AltName: Full=Protein-kinase C-related kinase 2;
GN   Name=PKN2; Synonyms=PRK2, PRKCL2;
DR   GuidetoPHARMACOLOGY; 1521; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043297; P:apical junction assembly; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0010631; P:epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PKN3_HUMAN              Reviewed;         889 AA.
AC   Q6P5Z2; Q9UM03;
DE   RecName: Full=Serine/threonine-protein kinase N3;
DE            EC=2.7.11.13;
DE   AltName: Full=Protein kinase PKN-beta;
DE   AltName: Full=Protein-kinase C-related kinase 3;
GN   Name=PKN3; Synonyms=PKNBETA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004697; F:protein kinase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0010631; P:epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PKNX2_HUMAN             Reviewed;         472 AA.
AC   Q96KN3; B7Z5I5; F5GZ15; Q63HL6; Q86XD1;
DE   RecName: Full=Homeobox protein PKNOX2;
DE   AltName: Full=Homeobox protein PREP-2;
DE   AltName: Full=PBX/knotted homeobox 2;
GN   Name=PKNOX2; Synonyms=PREP2;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   PKNX1_HUMAN             Reviewed;         436 AA.
AC   P55347; O00528; Q8IWT7;
DE   RecName: Full=Homeobox protein PKNOX1;
DE   AltName: Full=Homeobox protein PREP-1;
DE   AltName: Full=PBX/knotted homeobox 1;
GN   Name=PKNOX1; Synonyms=PREP1;
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PKP1_HUMAN              Reviewed;         747 AA.
AC   Q13835; O00645; Q14CA0; Q15152;
DE   RecName: Full=Plakophilin-1;
DE   AltName: Full=Band 6 protein;
DE            Short=B6P;
GN   Name=PKP1;
DR   GO; GO:0019215; F:intermediate filament binding; NAS:UniProtKB.
DR   GO; GO:0005521; F:lamin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0045110; P:intermediate filament bundle assembly; IDA:BHF-UCL.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   PKP2_HUMAN              Reviewed;         881 AA.
AC   Q99959; A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; Q4VC01; Q99960;
DE   RecName: Full=Plakophilin-2;
GN   Name=PKP2;
DR   GO; GO:0019215; F:intermediate filament binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0032947; F:protein complex scaffold; IMP:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; ISS:BHF-UCL.
DR   GO; GO:0034334; P:adherens junction maintenance; ISS:BHF-UCL.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0086001; P:cardiac muscle cell action potential; ISS:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; ISS:BHF-UCL.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0086019; P:cell-cell signaling involved in cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0002159; P:desmosome assembly; IMP:BHF-UCL.
DR   GO; GO:0016264; P:gap junction assembly; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0045110; P:intermediate filament bundle assembly; IMP:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0048496; P:maintenance of organ identity; IMP:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:2000810; P:regulation of tight junction assembly; ISS:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   PKP4_HUMAN              Reviewed;        1192 AA.
AC   Q99569; Q86W91;
DE   RecName: Full=Plakophilin-4;
DE   AltName: Full=p0071;
GN   Name=PKP4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0007043; P:cell-cell junction assembly; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; NAS:UniProtKB.
//
ID   PKP3_HUMAN              Reviewed;         797 AA.
AC   Q9Y446; F8J390; Q53EX8;
DE   RecName: Full=Plakophilin-3;
GN   Name=PKP3;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:UniProt.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:InterPro.
DR   GO; GO:0002159; P:desmosome assembly; IMP:UniProt.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IMP:UniProt.
//
ID   PKR1_HUMAN              Reviewed;         393 AA.
AC   Q8TCW9; A5JUU2; Q53QT9; Q8NFJ7;
DE   RecName: Full=Prokineticin receptor 1;
DE            Short=PK-R1;
DE   AltName: Full=G-protein coupled receptor 73;
DE   AltName: Full=G-protein coupled receptor ZAQ;
DE   AltName: Full=GPR73a;
GN   Name=PROKR1; Synonyms=GPR73, PKR1;
DR   GuidetoPHARMACOLOGY; 335; -.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
//
ID   PKR2_HUMAN              Reviewed;         384 AA.
AC   Q8NFJ6; A5JUU1; Q2M3C0; Q5TDY1; Q9NTT0;
DE   RecName: Full=Prokineticin receptor 2;
DE            Short=PK-R2;
DE   AltName: Full=G-protein coupled receptor 73-like 1;
DE   AltName: Full=GPR73b;
DE   AltName: Full=GPRg2;
GN   Name=PROKR2; Synonyms=GPR73L1, PKR2;
DR   GuidetoPHARMACOLOGY; 336; -.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
//
ID   PKRI1_HUMAN             Reviewed;         184 AA.
AC   Q9H875; Q8NDM6; Q96CF8;
DE   RecName: Full=PRKR-interacting protein 1;
GN   Name=PRKRIP1;
DR   GO; GO:0003725; F:double-stranded RNA binding; ISS:UniProt.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProt.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; ISS:UniProt.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; ISS:UniProt.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProt.
DR   GO; GO:0003014; P:renal system process; IDA:UniProt.
//
ID   PL8L1_HUMAN             Reviewed;         177 AA.
AC   A1L4L8;
DE   RecName: Full=PLAC8-like protein 1;
GN   Name=PLAC8L1;
//
ID   PLA1A_HUMAN             Reviewed;         456 AA.
AC   Q53H76; B2R8V2; B4DXA2; O95991; Q86WX6; Q9UPD2;
DE   RecName: Full=Phospholipase A1 member A;
DE            EC=3.1.1.-;
DE   AltName: Full=Phosphatidylserine-specific phospholipase A1;
DE            Short=PS-PLA1;
DE   Flags: Precursor;
GN   Name=PLA1A; Synonyms=NMD, PSPLA1;
DR   GO; GO:0008970; F:phosphatidylcholine 1-acylhydrolase activity; TAS:ProtInc.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006658; P:phosphatidylserine metabolic process; TAS:ProtInc.
//
ID   PLA2R_HUMAN             Reviewed;        1463 AA.
AC   Q13018; B2RTU9; D3DPB1; Q13019; Q15095; Q53R45; Q53RR7;
DE   RecName: Full=Secretory phospholipase A2 receptor;
DE            Short=PLA2-R;
DE            Short=PLA2R;
DE   AltName: Full=180 kDa secretory phospholipase A2 receptor;
DE   AltName: Full=C-type lectin domain family 13 member C;
DE   AltName: Full=M-type receptor;
DE   Contains:
DE     RecName: Full=Soluble secretory phospholipase A2 receptor;
DE              Short=Soluble PLA2-R;
DE              Short=Soluble PLA2R;
DE   Flags: Precursor;
GN   Name=PLA2R1; Synonyms=CLEC13C;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0043274; F:phospholipase binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001816; P:cytokine production; IMP:UniProtKB.
DR   GO; GO:1900139; P:negative regulation of arachidonic acid secretion; ISS:UniProtKB.
DR   GO; GO:1900138; P:negative regulation of phospholipase A2 activity; ISS:UniProtKB.
DR   GO; GO:0090403; P:oxidative stress-induced premature senescence; IMP:UniProtKB.
DR   GO; GO:0090238; P:positive regulation of arachidonic acid secretion; ISS:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:UniProtKB.
DR   GO; GO:0090399; P:replicative senescence; IMP:UniProtKB.
//
ID   PLAC1_HUMAN             Reviewed;         212 AA.
AC   Q9HBJ0;
DE   RecName: Full=Placenta-specific protein 1;
DE   Flags: Precursor;
GN   Name=PLAC1;
DR   GO; GO:0001890; P:placenta development; IEP:UniProtKB.
DR   GO; GO:0090214; P:spongiotrophoblast layer developmental growth; IEA:Ensembl.
//
ID   PLAC8_HUMAN             Reviewed;         115 AA.
AC   Q9NZF1; C1K3N2;
DE   RecName: Full=Placenta-specific gene 8 protein;
DE   AltName: Full=Protein C15;
GN   Name=PLAC8; ORFNames=BM-004;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
//
ID   PLAC4_HUMAN             Reviewed;         150 AA.
AC   Q8WY50;
DE   RecName: Full=Placenta-specific protein 4;
GN   Name=PLAC4; Synonyms=C21orf115, D21S418E; ORFNames=PP1416;
//
ID   PLAG1_HUMAN             Reviewed;         500 AA.
AC   Q6DJT9; B4DLC2; Q59GH8; Q9Y4L2;
DE   RecName: Full=Zinc finger protein PLAG1;
DE   AltName: Full=Pleiomorphic adenoma gene 1 protein;
GN   Name=PLAG1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0022612; P:gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060252; P:positive regulation of glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060736; P:prostate gland growth; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   PLAC9_HUMAN             Reviewed;          97 AA.
AC   Q5JTB6;
DE   RecName: Full=Placenta-specific protein 9;
DE   Flags: Precursor;
GN   Name=PLAC9;
//
ID   PLAK_HUMAN              Reviewed;         745 AA.
AC   P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9;
DE   RecName: Full=Junction plakoglobin;
DE   AltName: Full=Catenin gamma;
DE   AltName: Full=Desmoplakin III;
DE   AltName: Full=Desmoplakin-3;
GN   Name=JUP; Synonyms=CTNNG, DP3;
DR   GO; GO:0045294; F:alpha-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IBA:RefGenome.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005199; F:structural constituent of cell wall; IC:BHF-UCL.
DR   GO; GO:0005198; F:structural molecule activity; NAS:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; IBA:RefGenome.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IMP:BHF-UCL.
DR   GO; GO:0000902; P:cell morphogenesis; IBA:RefGenome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0071681; P:cellular response to indole-3-methanol; IDA:UniProtKB.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:BHF-UCL.
DR   GO; GO:0002159; P:desmosome assembly; IDA:BHF-UCL.
DR   GO; GO:0050982; P:detection of mechanical stimulus; IDA:BHF-UCL.
DR   GO; GO:0007398; P:ectoderm development; IBA:RefGenome.
DR   GO; GO:0071603; P:endothelial cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IMP:UniProt.
DR   GO; GO:0007369; P:gastrulation; IBA:RefGenome.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IBA:RefGenome.
DR   GO; GO:0003136; P:negative regulation of heart induction by canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0003308; P:negative regulation of Wnt signaling pathway involved in heart development; IBA:RefGenome.
DR   GO; GO:0007399; P:nervous system development; IBA:RefGenome.
DR   GO; GO:0048599; P:oocyte development; IBA:RefGenome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IC:BHF-UCL.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0043588; P:skin development; IBA:RefGenome.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   PLAL1_HUMAN             Reviewed;         463 AA.
AC   Q9UM63; B2RBA4; B2RCM8; E1P595; E1P597; O76019; Q7Z3V8; Q92981;
AC   Q96JR9; Q9UIZ0;
DE   RecName: Full=Zinc finger protein PLAGL1;
DE   AltName: Full=Lost on transformation 1;
DE            Short=LOT-1;
DE   AltName: Full=Pleiomorphic adenoma-like protein 1;
DE   AltName: Full=Tumor suppressor ZAC;
GN   Name=PLAGL1; Synonyms=LOT1, ZAC;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   PLAL2_HUMAN             Reviewed;         496 AA.
AC   Q9UPG8; A8K8T5; E1P5M3; Q92584;
DE   RecName: Full=Zinc finger protein PLAGL2;
DE   AltName: Full=Pleiomorphic adenoma-like protein 2;
GN   Name=PLAGL2; Synonyms=KIAA0198;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0034378; P:chylomicron assembly; IBA:RefGenome.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
//
ID   PLAP_HUMAN              Reviewed;         795 AA.
AC   Q9Y263; Q53EU5; Q5VY33; Q9NUL8; Q9NVE9; Q9UF53; Q9Y5L1;
DE   RecName: Full=Phospholipase A-2-activating protein;
DE            Short=PLA2P;
DE            Short=PLAP;
GN   Name=PLAA; Synonyms=PLAP;
DR   GO; GO:0016005; F:phospholipase A2 activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PLB1_HUMAN              Reviewed;        1458 AA.
AC   Q6P1J6; A8KAX2; Q53S03; Q8IUP7; Q96DP9;
DE   RecName: Full=Phospholipase B1, membrane-associated;
DE            Short=Phospholipase B;
DE            Short=hPLB;
DE   AltName: Full=Phospholipase B/lipase;
DE            Short=PLB/LIP;
DE   Includes:
DE     RecName: Full=Phospholipase A2;
DE              EC=3.1.1.4;
DE   Includes:
DE     RecName: Full=Lysophospholipase;
DE              EC=3.1.1.5;
DE   Flags: Precursor;
GN   Name=PLB1; Synonyms=PLB;
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLBL1_HUMAN             Reviewed;         553 AA.
AC   Q6P4A8; A8K4E9; Q9BVV3; Q9H625;
DE   RecName: Full=Phospholipase B-like 1;
DE            EC=3.1.1.-;
DE   AltName: Full=LAMA-like protein 1;
DE   AltName: Full=Lamina ancestor homolog 1;
DE   AltName: Full=Phospholipase B domain-containing protein 1;
DE   Contains:
DE     RecName: Full=Phospholipase B-like 1 chain A;
DE   Contains:
DE     RecName: Full=Phospholipase B-like 1 chain B;
DE   Contains:
DE     RecName: Full=Phospholipase B-like 1 chain C;
DE   Flags: Precursor;
GN   Name=PLBD1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLBL2_HUMAN             Reviewed;         589 AA.
AC   Q8NHP8;
DE   RecName: Full=Putative phospholipase B-like 2;
DE            EC=3.1.1.-;
DE   AltName: Full=76 kDa protein;
DE            Short=p76;
DE   AltName: Full=LAMA-like protein 2;
DE   AltName: Full=Lamina ancestor homolog 2;
DE   AltName: Full=Phospholipase B domain-containing protein 2;
DE   Contains:
DE     RecName: Full=Putative phospholipase B-like 2 32 kDa form;
DE   Contains:
DE     RecName: Full=Putative phospholipase B-like 2 45 kDa form;
DE   Flags: Precursor;
GN   Name=PLBD2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   PLCA_HUMAN              Reviewed;         283 AA.
AC   Q99943; A2BFI5; Q5BL03;
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase alpha;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 1;
DE            Short=1-AGP acyltransferase 1;
DE            Short=1-AGPAT 1;
DE   AltName: Full=Lysophosphatidic acid acyltransferase alpha;
DE            Short=LPAAT-alpha;
DE   AltName: Full=Protein G15;
DE   Flags: Precursor;
GN   Name=AGPAT1; Synonyms=G15;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IGI:BHF-UCL.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IGI:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IMP:BHF-UCL.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   PLCB2_HUMAN             Reviewed;        1185 AA.
AC   Q00722; A8K6J2; B9EGH5;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-beta-2;
DE   AltName: Full=Phospholipase C-beta-2;
DE            Short=PLC-beta-2;
GN   Name=PLCB2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.
DR   GO; GO:0050913; P:sensory perception of bitter taste; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   PLCB1_HUMAN             Reviewed;        1216 AA.
AC   Q9NQ66; D3DW12; D3DW13; O60325; Q17RQ6; Q5TFF7; Q5TGC9; Q8IV93;
AC   Q9BQW2; Q9H4H2; Q9H8H5; Q9NQ65; Q9NQH9; Q9NTH4; Q9UJP6; Q9UM26;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1;
DE            EC=3.1.4.11;
DE   AltName: Full=PLC-154;
DE   AltName: Full=Phosphoinositide phospholipase C-beta-1;
DE   AltName: Full=Phospholipase C-I;
DE            Short=PLC-I;
DE   AltName: Full=Phospholipase C-beta-1;
DE            Short=PLC-beta-1;
GN   Name=PLCB1; Synonyms=KIAA0581;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005516; F:calmodulin binding; IPI:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:BHF-UCL.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; NAS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0060466; P:activation of meiosis involved in egg activation; ISS:BHF-UCL.
DR   GO; GO:0021987; P:cerebral cortex development; ISS:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:BHF-UCL.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035722; P:interleukin-12-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035723; P:interleukin-15-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007613; P:memory; ISS:BHF-UCL.
DR   GO; GO:2000438; P:negative regulation of monocyte extravasation; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; ISS:BHF-UCL.
DR   GO; GO:2000344; P:positive regulation of acrosome reaction; ISS:BHF-UCL.
DR   GO; GO:2000560; P:positive regulation of CD24 biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0048639; P:positive regulation of developmental growth; ISS:BHF-UCL.
DR   GO; GO:0040019; P:positive regulation of embryonic development; ISS:BHF-UCL.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; ISS:BHF-UCL.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0080154; P:regulation of fertilization; ISS:BHF-UCL.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   PLCB3_HUMAN             Reviewed;        1234 AA.
AC   Q01970; A5PKZ6; G5E960; Q8N1A4;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-beta-3;
DE   AltName: Full=Phospholipase C-beta-3;
DE            Short=PLC-beta-3;
GN   Name=PLCB3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005516; F:calmodulin binding; IPI:BHF-UCL.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0003073; P:regulation of systemic arterial blood pressure; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   PLCB4_HUMAN             Reviewed;        1175 AA.
AC   Q15147; B7ZLK6; Q17R56; Q5JYS8; Q5JYT0; Q5JYT3; Q5JYT4; Q9BQW5;
AC   Q9BQW6; Q9BQW8; Q9UJQ2;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-beta-4;
DE   AltName: Full=Phospholipase C-beta-4;
DE            Short=PLC-beta-4;
GN   Name=PLCB4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLCB_HUMAN              Reviewed;         278 AA.
AC   O15120; O00516; O15106; Q5VUD3; Q5VUD4; Q9BSV7; Q9BWR7;
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase beta;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2;
DE            Short=1-AGP acyltransferase 2;
DE            Short=1-AGPAT 2;
DE   AltName: Full=Lysophosphatidic acid acyltransferase beta;
DE            Short=LPAAT-beta;
DE   Flags: Precursor;
GN   Name=AGPAT2;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IGI:BHF-UCL.
DR   GO; GO:0006644; P:phospholipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IMP:BHF-UCL.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   PLCC_HUMAN              Reviewed;         376 AA.
AC   Q9NRZ7; D3DSL2; Q3ZCU2; Q6UWP6; Q6ZUC6; Q8N3Q7; Q9NRZ6;
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase gamma;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 3;
DE            Short=1-AGP acyltransferase 3;
DE            Short=1-AGPAT 3;
DE   AltName: Full=Lysophosphatidic acid acyltransferase gamma;
DE            Short=LPAAT-gamma;
GN   Name=AGPAT3; Synonyms=LPAAT3; ORFNames=UNQ759/PRO1490;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   PLCD1_HUMAN             Reviewed;         756 AA.
AC   P51178; B3KR14; Q86VN8;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-delta-1;
DE   AltName: Full=Phospholipase C-III;
DE            Short=PLC-III;
DE   AltName: Full=Phospholipase C-delta-1;
DE            Short=PLC-delta-1;
GN   Name=PLCD1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0032794; F:GTPase activating protein binding; IPI:BHF-UCL.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLCD3_HUMAN             Reviewed;         789 AA.
AC   Q8N3E9; Q8TEC1; Q8TF37; Q96FL6;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-delta-3;
DE   AltName: Full=Phospholipase C-delta-3;
DE            Short=PLC-delta-3;
GN   Name=PLCD3; Synonyms=KIAA1964;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLCD4_HUMAN             Reviewed;         762 AA.
AC   Q9BRC7; Q53FS8;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4;
DE            Short=hPLCD4;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-delta-4;
DE   AltName: Full=Phospholipase C-delta-4;
DE            Short=PLC-delta-4;
GN   Name=PLCD4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; IEA:InterPro.
//
ID   PLCD_HUMAN              Reviewed;         378 AA.
AC   Q9NRZ5; Q5TEF0;
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase delta;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 4;
DE            Short=1-AGP acyltransferase 4;
DE            Short=1-AGPAT 4;
DE   AltName: Full=Lysophosphatidic acid acyltransferase delta;
DE            Short=LPAAT-delta;
GN   Name=AGPAT4; ORFNames=UNQ499/PRO1016;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   PLCE1_HUMAN             Reviewed;        2302 AA.
AC   Q9P212; A6NGW0; A6NLA1; A7MBN7; A8K1D7; B9EIJ6; Q1X6H8; Q5VWL4;
AC   Q5VWL5; Q9H9X8; Q9HBX6; Q9HC53; Q9UHV3;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1;
DE            EC=3.1.4.11;
DE   AltName: Full=Pancreas-enriched phospholipase C;
DE   AltName: Full=Phosphoinositide phospholipase C-epsilon-1;
DE   AltName: Full=Phospholipase C-epsilon-1;
DE            Short=PLC-epsilon-1;
GN   Name=PLCE1; Synonyms=KIAA1516, PLCE, PPLC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0004629; F:phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017016; F:Ras GTPase binding; TAS:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0006651; P:diacylglycerol biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0032835; P:glomerulus development; IMP:HGNC.
DR   GO; GO:0007507; P:heart development; TAS:UniProtKB.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0048016; P:inositol phosphate-mediated signaling; TAS:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; IC:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:UniProtKB.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0046578; P:regulation of Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLCE_HUMAN              Reviewed;         364 AA.
AC   Q9NUQ2; Q8IZ47; Q9BQG4;
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon;
DE            EC=2.3.1.51;
DE   AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 5;
DE            Short=1-AGP acyltransferase 5;
DE            Short=1-AGPAT 5;
DE   AltName: Full=Lysophosphatidic acid acyltransferase epsilon;
DE            Short=LPAAT-epsilon;
GN   Name=AGPAT5;
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   PLCG1_HUMAN             Reviewed;        1290 AA.
AC   P19174; B7ZLY7; B9EGH4; E1P5W4; Q2V575;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;
DE            EC=3.1.4.11;
DE   AltName: Full=PLC-148;
DE   AltName: Full=Phosphoinositide phospholipase C-gamma-1;
DE   AltName: Full=Phospholipase C-II;
DE            Short=PLC-II;
DE   AltName: Full=Phospholipase C-gamma-1;
DE            Short=PLC-gamma-1;
GN   Name=PLCG1; Synonyms=PLC1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PLCG2_HUMAN             Reviewed;        1265 AA.
AC   P16885; D3DUL3; Q3ZTS2; Q59H45; Q969T5;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-gamma-2;
DE   AltName: Full=Phospholipase C-IV;
DE            Short=PLC-IV;
DE   AltName: Full=Phospholipase C-gamma-2;
DE            Short=PLC-gamma-2;
GN   Name=PLCG2;
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0032237; P:activation of store-operated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0002316; P:follicular B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0032959; P:inositol trisphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; TAS:UniProtKB.
//
ID   PLCH1_HUMAN             Reviewed;        1693 AA.
AC   Q4KWH8; Q29RV9; Q4KWH9; Q68CN0; Q86XK4; Q9H9U2; Q9UPT3;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-eta-1;
DE   AltName: Full=Phospholipase C-eta-1;
DE            Short=PLC-eta-1;
DE   AltName: Full=Phospholipase C-like protein 3;
DE            Short=PLC-L3;
GN   Name=PLCH1; Synonyms=KIAA1069, PLCL3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050429; F:calcium-dependent phospholipase C activity; IDA:MGI.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLCH2_HUMAN             Reviewed;        1416 AA.
AC   O75038; A2VCM3; B9DI80; Q3LUA8; Q86XJ2; Q86XU1; Q86YU7; Q8TEH5;
AC   Q8WUS6;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-eta-2;
DE   AltName: Full=Phosphoinositide phospholipase C-like 4;
DE            Short=PLC-L4;
DE            Short=Phospholipase C-like protein 4;
DE   AltName: Full=Phospholipase C-eta-2;
DE            Short=PLC-eta2;
GN   Name=PLCH2; Synonyms=KIAA0450, PLCL4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLCL2_HUMAN             Reviewed;        1127 AA.
AC   Q9UPR0; A8K5V4; Q8N498; Q9H8L0; Q9UFP9;
DE   RecName: Full=Inactive phospholipase C-like protein 2;
DE            Short=PLC-L(2);
DE            Short=PLC-L2;
DE            Short=Phospholipase C-L2;
DE   AltName: Full=Phospholipase C-epsilon-2;
DE            Short=PLC-epsilon-2;
GN   Name=PLCL2; Synonyms=KIAA1092, PLCE2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050811; F:GABA receptor binding; IDA:MGI.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   PLCL1_HUMAN             Reviewed;        1095 AA.
AC   Q15111; Q3MJ90; Q53SD3; Q7Z3S3;
DE   RecName: Full=Inactive phospholipase C-like protein 1;
DE            Short=PLC-L1;
DE   AltName: Full=Phospholipase C-deleted in lung carcinoma;
DE   AltName: Full=Phospholipase C-related but catalytically inactive protein;
DE            Short=PRIP;
GN   Name=PLCL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:InterPro.
DR   GO; GO:0004629; F:phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
//
ID   PLCX1_HUMAN             Reviewed;         323 AA.
AC   Q9NUJ7; A2BH51; A2BH52;
DE   RecName: Full=PI-PLC X domain-containing protein 1;
GN   Name=PLCXD1;
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   PLCX2_HUMAN             Reviewed;         305 AA.
AC   Q0VAA5; Q96N12;
DE   RecName: Full=PI-PLC X domain-containing protein 2;
GN   Name=PLCXD2;
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   PLCX3_HUMAN             Reviewed;         321 AA.
AC   Q63HM9; A6NL04;
DE   RecName: Full=PI-PLC X domain-containing protein 3;
GN   Name=PLCXD3;
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   PLCZ1_HUMAN             Reviewed;         608 AA.
AC   Q86YW0; Q08AQ7; Q96J70;
DE   RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1;
DE            EC=3.1.4.11;
DE   AltName: Full=Phosphoinositide phospholipase C-zeta-1;
DE   AltName: Full=Phospholipase C-zeta-1;
DE            Short=PLC-zeta-1;
DE   AltName: Full=Testis-development protein NYD-SP27;
GN   Name=PLCZ1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:UniProtKB-EC.
DR   GO; GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007343; P:egg activation; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLD1_HUMAN              Reviewed;        1074 AA.
AC   Q13393;
DE   RecName: Full=Phospholipase D1;
DE            Short=PLD 1;
DE            Short=hPLD1;
DE            EC=3.1.4.4;
DE   AltName: Full=Choline phosphatase 1;
DE   AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D1;
GN   Name=PLD1;
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0004630; F:phospholipase D activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLD2_HUMAN              Reviewed;         933 AA.
AC   O14939; I3L2C9; O43540; O43579; O43580; Q6PGR0; Q96BY3;
DE   RecName: Full=Phospholipase D2;
DE            Short=PLD 2;
DE            Short=hPLD2;
DE            EC=3.1.4.4;
DE   AltName: Full=Choline phosphatase 2;
DE   AltName: Full=PLD1C;
DE   AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D2;
GN   Name=PLD2;
DR   GuidetoPHARMACOLOGY; 1434; -.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0004630; F:phospholipase D activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLD3_HUMAN              Reviewed;         490 AA.
AC   Q8IV08; Q92853; Q9BW87;
DE   RecName: Full=Phospholipase D3;
DE            Short=PLD 3;
DE            EC=3.1.4.4;
DE   AltName: Full=Choline phosphatase 3;
DE   AltName: Full=HindIII K4L homolog;
DE   AltName: Full=Hu-K4;
DE   AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D3;
GN   Name=PLD3;
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0004630; F:phospholipase D activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLD4_HUMAN              Reviewed;         506 AA.
AC   Q96BZ4; Q6UWD2;
DE   RecName: Full=Phospholipase D4;
DE            Short=PLD 4;
DE            EC=3.1.4.4;
DE   AltName: Full=Choline phosphatase 4;
DE   AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D4;
GN   Name=PLD4; Synonyms=C14orf175; ORFNames=UNQ2488/PRO5775;
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0004435; F:phosphatidylinositol phospholipase C activity; TAS:Reactome.
DR   GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLD5_HUMAN              Reviewed;         536 AA.
AC   Q8N7P1; A1KXV0; B7Z324; Q494U9; Q8NB22;
DE   RecName: Full=Inactive phospholipase D5;
DE            Short=Inactive PLD 5;
DE   AltName: Full=Inactive choline phosphatase 5;
DE   AltName: Full=Inactive phosphatidylcholine-hydrolyzing phospholipase D5;
DE   AltName: Full=PLDc;
GN   Name=PLD5;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   PLD6_HUMAN              Reviewed;         252 AA.
AC   Q8N2A8; Q8N5Y1;
DE   RecName: Full=Mitochondrial cardiolipin hydrolase;
DE            EC=3.1.-.-;
DE   AltName: Full=Choline phosphatase 6;
DE   AltName: Full=Mitochondrial phospholipase;
DE            Short=MitoPLD;
DE   AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D6;
DE   AltName: Full=Phospholipase D6;
DE            Short=PLD 6;
DE   AltName: Full=Protein zucchini homolog;
GN   Name=PLD6;
DR   GO; GO:0035755; F:cardiolipin hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0008053; P:mitochondrial fusion; IMP:UniProtKB.
DR   GO; GO:0030719; P:P granule organization; ISS:UniProtKB.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
//
ID   PLDX1_HUMAN             Reviewed;         500 AA.
AC   Q8IUK5; B2R7I8; Q5QCZ7; Q5QCZ8; Q5QCZ9; Q9HCT9;
DE   RecName: Full=Plexin domain-containing protein 1;
DE   AltName: Full=Tumor endothelial marker 3;
DE   AltName: Full=Tumor endothelial marker 7;
DE   Flags: Precursor;
GN   Name=PLXDC1; Synonyms=TEM3, TEM7;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
//
ID   PLEC_HUMAN              Reviewed;        4684 AA.
AC   Q15149; Q15148; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380;
AC   Q6S381; Q6S382; Q6S383;
DE   RecName: Full=Plectin;
DE            Short=PCN;
DE            Short=PLTN;
DE   AltName: Full=Hemidesmosomal protein 1;
DE            Short=HD1;
DE   AltName: Full=Plectin-1;
GN   Name=PLEC; Synonyms=PLEC1;
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
//
ID   PLEK2_HUMAN             Reviewed;         353 AA.
AC   Q9NYT0; Q96JT0;
DE   RecName: Full=Pleckstrin-2;
GN   Name=PLEK2;
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   PLEK_HUMAN              Reviewed;         350 AA.
AC   P08567; B2R9E8; Q53SU8; Q6FGM8; Q6FGQ1; Q8WV81;
DE   RecName: Full=Pleckstrin;
DE   AltName: Full=Platelet 47 kDa protein;
DE            Short=p47;
GN   Name=PLEK; Synonyms=P47;
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IDA:BHF-UCL.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030030; P:cell projection organization; IDA:BHF-UCL.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IDA:BHF-UCL.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEP:BHF-UCL.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050849; P:negative regulation of calcium-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010920; P:negative regulation of inositol phosphate biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0046488; P:phosphatidylinositol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030845; P:phospholipase C-inhibiting G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; ISS:BHF-UCL.
DR   GO; GO:0002576; P:platelet degranulation; IEP:BHF-UCL.
DR   GO; GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:BHF-UCL.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; IDA:BHF-UCL.
DR   GO; GO:0010925; P:positive regulation of inositol-polyphosphate 5-phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0033625; P:positive regulation of integrin activation; ISS:BHF-UCL.
DR   GO; GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.
DR   GO; GO:0070528; P:protein kinase C signaling; ISS:BHF-UCL.
DR   GO; GO:0070560; P:protein secretion by platelet; ISS:BHF-UCL.
DR   GO; GO:0060305; P:regulation of cell diameter; IDA:BHF-UCL.
DR   GO; GO:0031529; P:ruffle organization; IDA:BHF-UCL.
DR   GO; GO:0070493; P:thrombin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; ISS:BHF-UCL.
//
ID   PLET1_HUMAN             Reviewed;         207 AA.
AC   Q6UQ28; Q6UQ24; Q6UQ25; Q6UQ27;
DE   RecName: Full=Placenta-expressed transcript 1 protein;
DE   Flags: Precursor;
GN   Name=PLET1; Synonyms=C11orf34;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; ISS:UniProtKB.
//
ID   PLF4_HUMAN              Reviewed;         101 AA.
AC   P02776; Q53X61; Q9UC64; Q9UC65;
DE   RecName: Full=Platelet factor 4;
DE            Short=PF-4;
DE   AltName: Full=C-X-C motif chemokine 4;
DE   AltName: Full=Iroplact;
DE   AltName: Full=Oncostatin-A;
DE   Contains:
DE     RecName: Full=Platelet factor 4, short form;
DE   Flags: Precursor;
GN   Name=PF4; Synonyms=CXCL4, SCYB4;
DR   GO; GO:0008009; F:chemokine activity; TAS:UniProtKB.
DR   GO; GO:0048248; F:CXCR3 chemokine receptor binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0030595; P:leukocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0045918; P:negative regulation of cytolysis; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:BHF-UCL.
DR   GO; GO:0045653; P:negative regulation of megakaryocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0045347; P:negative regulation of MHC class II biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; IDA:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030816; P:positive regulation of cAMP metabolic process; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IDA:UniProtKB.
//
ID   PLGA_HUMAN              Reviewed;          96 AA.
AC   Q15195;
DE   RecName: Full=Plasminogen-like protein A;
DE   AltName: Full=Plasminogen-like protein A1;
DE   AltName: Full=Plasminogen-related protein A;
DE   Flags: Precursor;
GN   Name=PLGLA; Synonyms=PLGLA1, PLGP2, PRGA;
//
ID   PLGB_HUMAN              Reviewed;          96 AA.
AC   Q02325; Q580R1;
DE   RecName: Full=Plasminogen-like protein B;
DE   AltName: Full=Plasminogen-related protein B;
DE   Flags: Precursor;
GN   Name=PLGLB1; Synonyms=PLGL, PRGB;
GN   and
GN   Name=PLGLB2; Synonyms=PLGP1;
//
ID   PLGF_HUMAN              Reviewed;         221 AA.
AC   P49763; Q07101; Q9BV78; Q9Y6S8;
DE   RecName: Full=Placenta growth factor;
DE            Short=PlGF;
DE   Flags: Precursor;
GN   Name=PGF; Synonyms=PGFL, PLGF;
DR   GO; GO:0008083; F:growth factor activity; IMP:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060688; P:regulation of morphogenesis of a branching structure; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; TAS:Reactome.
//
ID   PLHD1_HUMAN             Reviewed;         506 AA.
AC   A6NEE1; B9EJC2;
DE   RecName: Full=Pleckstrin homology domain-containing family D member 1;
DE            Short=PH domain-containing family D member 1;
GN   Name=PLEKHD1;
//
ID   PLIN1_HUMAN             Reviewed;         522 AA.
AC   O60240; Q8N5Y6;
DE   RecName: Full=Perilipin-1;
DE   AltName: Full=Lipid droplet-associated protein;
GN   Name=PLIN1; Synonyms=PERI, PLIN;
DR   GO; GO:0008289; F:lipid binding; NAS:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   PLIN2_HUMAN             Reviewed;         437 AA.
AC   Q99541; Q9BSC3;
DE   RecName: Full=Perilipin-2;
DE   AltName: Full=Adipophilin;
DE   AltName: Full=Adipose differentiation-related protein;
DE            Short=ADRP;
GN   Name=PLIN2; Synonyms=ADFP;
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0015909; P:long-chain fatty acid transport; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLIN3_HUMAN             Reviewed;         434 AA.
AC   O60664; A8K4Y9; K7EQF4; Q53G77; Q9BS03; Q9UBD7; Q9UP92;
DE   RecName: Full=Perilipin-3;
DE   AltName: Full=47 kDa mannose 6-phosphate receptor-binding protein;
DE            Short=47 kDa MPR-binding protein;
DE   AltName: Full=Cargo selection protein TIP47;
DE   AltName: Full=Mannose-6-phosphate receptor-binding protein 1;
DE   AltName: Full=Placental protein 17;
DE            Short=PP17;
GN   Name=PLIN3; Synonyms=M6PRBP1, TIP47;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   PLIN4_HUMAN             Reviewed;        1357 AA.
AC   Q96Q06; A6NEI2;
DE   RecName: Full=Perilipin-4;
DE   AltName: Full=Adipocyte protein S3-12;
GN   Name=PLIN4; Synonyms=KIAA1881;
//
ID   PLIN5_HUMAN             Reviewed;         463 AA.
AC   Q00G26; A2RRC1; Q6ZS68;
DE   RecName: Full=Perilipin-5;
DE   AltName: Full=Lipid storage droplet protein 5;
GN   Name=PLIN5; Synonyms=LSDP5, OXPAT, PAT-1;
DR   GO; GO:0034389; P:lipid particle organization; ISS:UniProtKB.
DR   GO; GO:0031999; P:negative regulation of fatty acid beta-oxidation; ISS:UniProtKB.
DR   GO; GO:0060192; P:negative regulation of lipase activity; ISS:UniProtKB.
DR   GO; GO:0035359; P:negative regulation of peroxisome proliferator activated receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; ISS:UniProtKB.
DR   GO; GO:0010897; P:negative regulation of triglyceride catabolic process; ISS:UniProtKB.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; ISS:UniProtKB.
DR   GO; GO:0060193; P:positive regulation of lipase activity; ISS:UniProtKB.
DR   GO; GO:0010884; P:positive regulation of lipid storage; ISS:UniProtKB.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; ISS:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.
//
ID   PLK1_HUMAN              Reviewed;         603 AA.
AC   P53350; Q15153; Q99746;
DE   RecName: Full=Serine/threonine-protein kinase PLK1;
DE            EC=2.7.11.21;
DE   AltName: Full=Polo-like kinase 1;
DE            Short=PLK-1;
DE   AltName: Full=Serine/threonine-protein kinase 13;
DE            Short=STPK13;
GN   Name=PLK1; Synonyms=PLK;
DR   GuidetoPHARMACOLOGY; 2168; -.
DR   GO; GO:0010997; F:anaphase-promoting complex binding; IPI:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; TAS:Reactome.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IMP:MGI.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000281; P:mitotic cytokinesis; IDA:UniProtKB.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0040038; P:polar body extrusion after meiotic divisions; IEA:Ensembl.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:UniProtKB.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031648; P:protein destabilization; IDA:UniProtKB.
DR   GO; GO:0071168; P:protein localization to chromatin; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:BHF-UCL.
DR   GO; GO:0043393; P:regulation of protein binding; IMP:BHF-UCL.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
//
ID   PLK2_HUMAN              Reviewed;         685 AA.
AC   Q9NYY3; O60679; Q96CV7; Q9UE61;
DE   RecName: Full=Serine/threonine-protein kinase PLK2;
DE            EC=2.7.11.21;
DE   AltName: Full=Polo-like kinase 2;
DE            Short=PLK-2;
DE            Short=hPlk2;
DE   AltName: Full=Serine/threonine-protein kinase SNK;
DE            Short=hSNK;
DE   AltName: Full=Serum-inducible kinase;
GN   Name=PLK2; Synonyms=SNK;
DR   GuidetoPHARMACOLOGY; 2169; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0060292; P:long term synaptic depression; ISS:UniProtKB.
DR   GO; GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.
DR   GO; GO:0007613; P:memory; ISS:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.
DR   GO; GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0046599; P:regulation of centriole replication; IDA:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
//
ID   PLK3_HUMAN              Reviewed;         646 AA.
AC   Q9H4B4; Q15767; Q5JR99; Q96CV1;
DE   RecName: Full=Serine/threonine-protein kinase PLK3;
DE            EC=2.7.11.21;
DE   AltName: Full=Cytokine-inducible serine/threonine-protein kinase;
DE   AltName: Full=FGF-inducible kinase;
DE   AltName: Full=Polo-like kinase 3;
DE            Short=PLK-3;
DE   AltName: Full=Proliferation-related kinase;
GN   Name=PLK3; Synonyms=CNK, FNK, PRK;
DR   GuidetoPHARMACOLOGY; 2170; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IMP:UniProtKB.
DR   GO; GO:0007113; P:endomitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:UniProtKB.
DR   GO; GO:0090166; P:Golgi disassembly; IDA:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; TAS:UniProtKB.
DR   GO; GO:0000084; P:mitotic S phase; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:2000777; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0051302; P:regulation of cell division; IDA:UniProtKB.
DR   GO; GO:0006970; P:response to osmotic stress; IDA:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; IDA:UniProtKB.
DR   GO; GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
//
ID   PLK4_HUMAN              Reviewed;         970 AA.
AC   O00444; B2RAL0; B7Z837; B7Z8G7; Q8IYF0; Q96Q95; Q9UD84; Q9UDE2;
DE   RecName: Full=Serine/threonine-protein kinase PLK4;
DE            EC=2.7.11.21;
DE   AltName: Full=Polo-like kinase 4;
DE            Short=PLK-4;
DE   AltName: Full=Serine/threonine-protein kinase 18;
DE   AltName: Full=Serine/threonine-protein kinase Sak;
GN   Name=PLK4; Synonyms=SAK, STK18;
DR   GuidetoPHARMACOLOGY; 2171; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0007099; P:centriole replication; IMP:UniProtKB.
DR   GO; GO:0098535; P:de novo centriole assembly; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046601; P:positive regulation of centriole replication; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
//
ID   PLLP_HUMAN              Reviewed;         182 AA.
AC   Q9Y342; B2R9T6;
DE   RecName: Full=Plasmolipin;
DE   AltName: Full=Plasma membrane proteolipid;
GN   Name=PLLP; Synonyms=PMLP, TM4SF11;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
//
ID   PLK5_HUMAN              Reviewed;         336 AA.
AC   Q496M5; B3KNR4; Q1ZYM0;
DE   RecName: Full=Inactive serine/threonine-protein kinase PLK5;
DE   AltName: Full=Polo-like kinase 5;
DE            Short=PLK-5;
GN   Name=PLK5; Synonyms=PLK5P; ORFNames=FG060302;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0002357; P:defense response to tumor cell; IDA:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006927; P:transformed cell apoptotic process; IMP:UniProtKB.
//
ID   PLMN_HUMAN              Reviewed;         810 AA.
AC   P00747; Q15146; Q5TEH4; Q6PA00;
DE   RecName: Full=Plasminogen;
DE            EC=3.4.21.7;
DE   Contains:
DE     RecName: Full=Plasmin heavy chain A;
DE   Contains:
DE     RecName: Full=Activation peptide;
DE   Contains:
DE     RecName: Full=Angiostatin;
DE   Contains:
DE     RecName: Full=Plasmin heavy chain A, short form;
DE   Contains:
DE     RecName: Full=Plasmin light chain B;
DE   Flags: Precursor;
GN   Name=PLG;
DR   GuidetoPHARMACOLOGY; 2394; -.
DR   GO; GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; IMP:HGNC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0022617; P:extracellular matrix disassembly; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0071674; P:mononuclear cell migration; IEA:Ensembl.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:2000048; P:negative regulation of cell-cell adhesion mediated by cadherin; TAS:BHF-UCL.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IDA:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0051919; P:positive regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:Ensembl.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
DR   GO; GO:0048771; P:tissue remodeling; IEA:UniProtKB-KW.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
//
ID   PLM_HUMAN               Reviewed;          92 AA.
AC   O00168; A8K196;
DE   RecName: Full=Phospholemman;
DE   AltName: Full=FXYD domain-containing ion transport regulator 1;
DE   Flags: Precursor;
GN   Name=FXYD1; Synonyms=PLM;
DR   GO; GO:0005254; F:chloride channel activity; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   PLOD1_HUMAN             Reviewed;         727 AA.
AC   Q02809; Q96AV9; Q9H132;
DE   RecName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1;
DE            EC=1.14.11.4;
DE   AltName: Full=Lysyl hydroxylase 1;
DE            Short=LH1;
DE   Flags: Precursor;
GN   Name=PLOD1; Synonyms=LLH, PLOD;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008475; F:procollagen-lysine 5-dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; IMP:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0046947; P:hydroxylysine biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
//
ID   PLOD3_HUMAN             Reviewed;         738 AA.
AC   O60568; B2R6W6; Q540C3;
DE   RecName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3;
DE            EC=1.14.11.4;
DE   AltName: Full=Lysyl hydroxylase 3;
DE            Short=LH3;
DE   Flags: Precursor;
GN   Name=PLOD3;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0050211; F:procollagen galactosyltransferase activity; TAS:Reactome.
DR   GO; GO:0033823; F:procollagen glucosyltransferase activity; TAS:Reactome.
DR   GO; GO:0008475; F:procollagen-lysine 5-dioxygenase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070831; P:basement membrane assembly; IEA:Ensembl.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0048730; P:epidermis morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060425; P:lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0042311; P:vasodilation; IEA:Ensembl.
//
ID   PLOD2_HUMAN             Reviewed;         737 AA.
AC   O00469; Q59ED2; Q8N170;
DE   RecName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2;
DE            EC=1.14.11.4;
DE   AltName: Full=Lysyl hydroxylase 2;
DE            Short=LH2;
DE   Flags: Precursor;
GN   Name=PLOD2;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008475; F:procollagen-lysine 5-dioxygenase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
//
ID   PLP2_HUMAN              Reviewed;         152 AA.
AC   Q04941; A6NDT7; Q32MM8;
DE   RecName: Full=Proteolipid protein 2;
DE   AltName: Full=Differentiation-dependent protein A4;
DE   AltName: Full=Intestinal membrane A4 protein;
GN   Name=PLP2; Synonyms=A4;
DR   GO; GO:0019956; F:chemokine binding; IPI:UniProtKB.
DR   GO; GO:0015075; F:ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006935; P:chemotaxis; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:ProtInc.
//
ID   PLPL1_HUMAN             Reviewed;         532 AA.
AC   Q8N8W4; A3RMU3; J3JS20; Q2A6N1; Q3SY95; Q3SY96; Q5R3L2;
DE   RecName: Full=Patatin-like phospholipase domain-containing protein 1;
DE            EC=3.1.1.-;
GN   Name=PNPLA1;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   PLPL2_HUMAN             Reviewed;         504 AA.
AC   Q96AD5; O60643; Q5EFF5; Q6XYE5; Q96ET6; Q9NQ61; Q9NQ62;
DE   RecName: Full=Patatin-like phospholipase domain-containing protein 2;
DE            EC=3.1.1.3;
DE   AltName: Full=Adipose triglyceride lipase;
DE   AltName: Full=Calcium-independent phospholipase A2;
DE   AltName: Full=Desnutrin;
DE   AltName: Full=IPLA2-zeta;
DE   AltName: Full=Pigment epithelium-derived factor;
DE   AltName: Full=TTS2.2;
DE   AltName: Full=Transport-secretion protein 2;
DE            Short=TTS2;
GN   Name=PNPLA2; Synonyms=ATGL; ORFNames=FP17548;
DR   GO; GO:0004806; F:triglyceride lipase activity; ISS:UniProtKB.
DR   GO; GO:0036155; P:acylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0010891; P:negative regulation of sequestering of triglyceride; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0010898; P:positive regulation of triglyceride catabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; IEA:UniProtKB-UniPathway.
//
ID   PLPL3_HUMAN             Reviewed;         481 AA.
AC   Q9NST1; B0QYI0; B2RCL3; B3KW00; Q6P1A1; Q96CB4;
DE   RecName: Full=Patatin-like phospholipase domain-containing protein 3;
DE            EC=3.1.1.3;
DE   AltName: Full=Acylglycerol O-acyltransferase;
DE            EC=2.3.1.-;
DE   AltName: Full=Adiponutrin;
DE   AltName: Full=Calcium-independent phospholipase A2-epsilon;
DE            Short=iPLA2-epsilon;
GN   Name=PNPLA3; Synonyms=ADPN, C22orf20;
DR   GO; GO:0051265; F:diolein transacylation activity; IDA:UniProtKB.
DR   GO; GO:0051264; F:mono-olein transacylation activity; IDA:UniProtKB.
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0004806; F:triglyceride lipase activity; IDA:UniProtKB.
DR   GO; GO:0036155; P:acylglycerol acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019433; P:triglyceride catabolic process; IDA:UniProtKB.
//
ID   PLPL5_HUMAN             Reviewed;         429 AA.
AC   Q7Z6Z6; B1AHL8; B3KPR1; Q6ZST0;
DE   RecName: Full=Patatin-like phospholipase domain-containing protein 5;
DE            EC=3.1.1.-;
DE   AltName: Full=GS2-like protein;
GN   Name=PNPLA5; Synonyms=GS2L;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   PLPL7_HUMAN             Reviewed;        1317 AA.
AC   Q6ZV29; B5MDD3; Q5T364; Q658X0; Q658Y3; Q6ZTS1; Q86YU8; Q8TAY5;
AC   Q96N75; Q9H7N5;
DE   RecName: Full=Patatin-like phospholipase domain-containing protein 7;
DE            EC=3.1.1.-;
GN   Name=PNPLA7; Synonyms=C9orf111;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   PLPL4_HUMAN             Reviewed;         253 AA.
AC   P41247; A8K1H3; B4E362; Q8WW83;
DE   RecName: Full=Patatin-like phospholipase domain-containing protein 4;
DE            EC=3.1.1.3;
DE   AltName: Full=Protein GS2;
GN   Name=PNPLA4; Synonyms=DXS1283E, GS2;
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
//
ID   PLPL6_HUMAN             Reviewed;        1366 AA.
AC   Q8IY17; A6NGQ0; B4DFB9; B7Z7T2; F5H5K9; J3KQS3; O60859; Q86W58;
AC   Q9UG58;
DE   RecName: Full=Neuropathy target esterase;
DE            EC=3.1.1.5;
DE   AltName: Full=Patatin-like phospholipase domain-containing protein 6;
GN   Name=PNPLA6; Synonyms=NTE;
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IEA:InterPro.
//
ID   PLPL8_HUMAN             Reviewed;         782 AA.
AC   Q9NP80; A4D0S1; C9JZI4; O95035; Q8N3I3; Q9H7T5; Q9NR17; Q9NUN2;
AC   Q9NZ79;
DE   RecName: Full=Calcium-independent phospholipase A2-gamma;
DE            EC=3.1.1.5;
DE   AltName: Full=Intracellular membrane-associated calcium-independent phospholipase A2 gamma;
DE            Short=iPLA2-gamma;
DE   AltName: Full=PNPLA-gamma;
DE   AltName: Full=Patatin-like phospholipase domain-containing protein 8;
DE   AltName: Full=iPLA2-2;
GN   Name=PNPLA8; Synonyms=IPLA22, IPLA2G; ORFNames=BM-043;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0047499; F:calcium-independent phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0050482; P:arachidonic acid secretion; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0043651; P:linoleic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0034638; P:phosphatidylcholine catabolic process; IDA:UniProtKB.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0046338; P:phosphatidylethanolamine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PLPL9_HUMAN             Reviewed;         806 AA.
AC   O60733; A8K597; B0QYE8; O75645; Q8N452; Q9UG29; Q9UIT0; Q9Y671;
DE   RecName: Full=85/88 kDa calcium-independent phospholipase A2;
DE            Short=CaI-PLA2;
DE            EC=3.1.1.4;
DE   AltName: Full=Group VI phospholipase A2;
DE            Short=GVI PLA2;
DE   AltName: Full=Intracellular membrane-associated calcium-independent phospholipase A2 beta;
DE            Short=iPLA2-beta;
DE   AltName: Full=Patatin-like phospholipase domain-containing protein 9;
DE            Short=PNPLA9;
GN   Name=PLA2G6; Synonyms=PLPLA9;
DR   GO; GO:0047499; F:calcium-independent phospholipase A2 activity; IEA:Ensembl.
DR   GO; GO:0004623; F:phospholipase A2 activity; TAS:ProtInc.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0051967; P:negative regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0090238; P:positive regulation of arachidonic acid secretion; IEA:Ensembl.
DR   GO; GO:2000304; P:positive regulation of ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:1901339; P:regulation of store-operated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0014832; P:urinary bladder smooth muscle contraction; IEA:Ensembl.
//
ID   PLPP_HUMAN              Reviewed;         296 AA.
AC   Q96GD0; Q9UGY2;
DE   RecName: Full=Pyridoxal phosphate phosphatase;
DE            Short=PLP phosphatase;
DE            EC=3.1.3.3;
DE            EC=3.1.3.74;
DE   AltName: Full=Chronophin;
GN   Name=PDXP; Synonyms=CIN, PLP, PLPP;
DR   GO; GO:0031072; F:heat shock protein binding; IDA:MGI.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004647; F:phosphoserine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033883; F:pyridoxal phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0031247; P:actin rod assembly; IDA:MGI.
DR   GO; GO:0071318; P:cellular response to ATP; IDA:MGI.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; IMP:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0032361; P:pyridoxal phosphate catabolic process; ISS:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; IMP:UniProtKB.
//
ID   PLRG1_HUMAN             Reviewed;         514 AA.
AC   O43660; B3KMK4; Q3KQY5; Q8WUD8;
DE   RecName: Full=Pleiotropic regulator 1;
GN   Name=PLRG1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   PLRKT_HUMAN             Reviewed;         147 AA.
AC   Q9HBL7; B2R6W0; Q9NZ44;
DE   RecName: Full=Plasminogen receptor (KT);
DE            Short=Plg-R(KT);
GN   Name=PLGRKT; Synonyms=C9orf46; ORFNames=AD025, MDS030;
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0010756; P:positive regulation of plasminogen activation; IEA:Ensembl.
//
ID   PLS1_HUMAN              Reviewed;         318 AA.
AC   O15162; B2R8H8;
DE   RecName: Full=Phospholipid scramblase 1;
DE            Short=PL scramblase 1;
DE   AltName: Full=Ca(2+)-dependent phospholipid scramblase 1;
DE   AltName: Full=Erythrocyte phospholipid scramblase;
DE   AltName: Full=MmTRA1b;
GN   Name=PLSCR1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0017128; F:phospholipid scramblase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IDA:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0006659; P:phosphatidylserine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0017121; P:phospholipid scrambling; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
DR   GO; GO:2000373; P:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060368; P:regulation of Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.
DR   GO; GO:0033003; P:regulation of mast cell activation; ISS:UniProtKB.
DR   GO; GO:0035456; P:response to interferon-beta; IMP:UniProtKB.
//
ID   PLS2_HUMAN              Reviewed;         224 AA.
AC   Q9NRY7; B4DXC3; J3KR76; Q0VAQ1; Q6NSW9;
DE   RecName: Full=Phospholipid scramblase 2;
DE            Short=PL scramblase 2;
DE   AltName: Full=Ca(2+)-dependent phospholipid scramblase 2;
GN   Name=PLSCR2;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0017128; F:phospholipid scramblase activity; NAS:UniProtKB.
DR   GO; GO:0017121; P:phospholipid scrambling; NAS:UniProtKB.
//
ID   PLS3_HUMAN              Reviewed;         295 AA.
AC   Q9NRY6; A8K252; Q567U0; Q8NBW6; Q96F13;
DE   RecName: Full=Phospholipid scramblase 3;
DE            Short=PL scramblase 3;
DE   AltName: Full=Ca(2+)-dependent phospholipid scramblase 3;
GN   Name=PLSCR3;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0017128; F:phospholipid scramblase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0042632; P:cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0017121; P:phospholipid scrambling; NAS:UniProtKB.
//
ID   PLS4_HUMAN              Reviewed;         329 AA.
AC   Q9NRQ2; A8K2E9; Q2TTR3; Q658L3; Q6ZR73; Q7Z505;
DE   RecName: Full=Phospholipid scramblase 4;
DE            Short=PL scramblase 4;
DE   AltName: Full=Ca(2+)-dependent phospholipid scramblase 4;
DE   AltName: Full=Cell growth-inhibiting gene 43 protein;
DE   AltName: Full=TRA1;
GN   Name=PLSCR4; ORFNames=GIG43;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0017128; F:phospholipid scramblase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0017121; P:phospholipid scrambling; NAS:UniProtKB.
//
ID   PLS5_HUMAN              Reviewed;         271 AA.
AC   A0PG75; B2RXK5;
DE   RecName: Full=Phospholipid scramblase family member 5;
GN   Name=PLSCR5;
//
ID   PLSI_HUMAN              Reviewed;         629 AA.
AC   Q14651; A8K2Q1; D3DNG3; Q8NEG6;
DE   RecName: Full=Plastin-1;
DE   AltName: Full=Intestine-specific plastin;
DE            Short=I-plastin;
GN   Name=PLS1;
DR   GO; GO:0051015; F:actin filament binding; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
//
ID   PLSL_HUMAN              Reviewed;         627 AA.
AC   P13796; B2R613; Q5TBN4;
DE   RecName: Full=Plastin-2;
DE   AltName: Full=L-plastin;
DE   AltName: Full=LC64P;
DE   AltName: Full=Lymphocyte cytosolic protein 1;
DE            Short=LCP-1;
GN   Name=LCP1; Synonyms=PLS2;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; IMP:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; IMP:UniProt.
DR   GO; GO:0016477; P:cell migration; IMP:UniProt.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0010737; P:protein kinase A signaling; IMP:UniProt.
DR   GO; GO:0033157; P:regulation of intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IDA:UniProtKB.
//
ID   PLST_HUMAN              Reviewed;         630 AA.
AC   P13797; A8K579; B1AQ09; Q86YI6;
DE   RecName: Full=Plastin-3;
DE   AltName: Full=T-plastin;
GN   Name=PLS3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0060348; P:bone development; IMP:UniProtKB.
//
ID   PLTP_HUMAN              Reviewed;         493 AA.
AC   P55058; A8K006; B4DDD5; B4DRB4; E1P5N8; E7EV16; Q8WTT1; Q9BR07;
AC   Q9BSH8;
DE   RecName: Full=Phospholipid transfer protein;
DE   AltName: Full=Lipid transfer protein II;
DE   Flags: Precursor;
GN   Name=PLTP;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0010189; P:vitamin E biosynthetic process; IEA:Ensembl.
//
ID   PLVAP_HUMAN             Reviewed;         442 AA.
AC   Q9BX97; Q86VP0; Q8N8Y0; Q8ND68; Q8TER8; Q9BZD5;
DE   RecName: Full=Plasmalemma vesicle-associated protein;
DE   AltName: Full=Fenestrated endothelial-linked structure protein;
DE   AltName: Full=Plasmalemma vesicle protein 1;
DE            Short=PV-1;
GN   Name=PLVAP; Synonyms=FELS, PV1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProt.
DR   GO; GO:0002693; P:positive regulation of cellular extravasation; IMP:UniProt.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProt.
//
ID   PLXA1_HUMAN             Reviewed;        1896 AA.
AC   Q9UIW2;
DE   RecName: Full=Plexin-A1;
DE   AltName: Full=Semaphorin receptor NOV;
DE   Flags: Precursor;
GN   Name=PLXNA1; Synonyms=NOV, PLXN1;
DR   GO; GO:0004872; F:receptor activity; TAS:UniProtKB.
DR   GO; GO:0017154; F:semaphorin receptor activity; TAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060666; P:dichotomous subdivision of terminal units involved in salivary gland branching; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0014910; P:regulation of smooth muscle cell migration; IEA:Ensembl.
//
ID   PLXA2_HUMAN             Reviewed;        1894 AA.
AC   O75051; A2RTX9; B2RMX7; Q6UX61; Q96GN9; Q9BRL1; Q9UIW1;
DE   RecName: Full=Plexin-A2;
DE   AltName: Full=Semaphorin receptor OCT;
DE   Flags: Precursor;
GN   Name=PLXNA2; Synonyms=KIAA0463, OCT, PLXN2; ORFNames=UNQ209/PRO235;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017154; F:semaphorin receptor activity; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0021935; P:cerebellar granule cell precursor tangential migration; IEA:Ensembl.
DR   GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   PLXA3_HUMAN             Reviewed;        1871 AA.
AC   P51805; Q5HY36;
DE   RecName: Full=Plexin-A3;
DE   AltName: Full=Plexin-4;
DE   AltName: Full=Semaphorin receptor SEX;
DE   Flags: Precursor;
GN   Name=PLXNA3; Synonyms=PLXN4, SEX;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017154; F:semaphorin receptor activity; IEA:Ensembl.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; IEA:Ensembl.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0051495; P:positive regulation of cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0021860; P:pyramidal neuron development; IEA:Ensembl.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; NAS:BHF-UCL.
//
ID   PLXA4_HUMAN             Reviewed;        1894 AA.
AC   Q9HCM2; A4D1N6; E9PAM2; Q6UWC6; Q6ZW89; Q8N969; Q8ND00; Q8NEN3;
AC   Q9NTD4;
DE   RecName: Full=Plexin-A4;
DE   Flags: Precursor;
GN   Name=PLXNA4; Synonyms=KIAA1550, PLXNA4A, PLXNA4B;
GN   ORFNames=UNQ2820/PRO34003;
DR   GO; GO:0017154; F:semaphorin receptor activity; IEA:Ensembl.
DR   GO; GO:0021960; P:anterior commissure morphogenesis; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0021793; P:chemorepulsion of branchiomotor axon; IEA:Ensembl.
DR   GO; GO:0021610; P:facial nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0021615; P:glossopharyngeal nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0021784; P:postganglionic parasympathetic nervous system development; IEA:Ensembl.
DR   GO; GO:0048841; P:regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0050923; P:regulation of negative chemotaxis; IEA:Ensembl.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0048485; P:sympathetic nervous system development; IEA:Ensembl.
DR   GO; GO:0021636; P:trigeminal nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0021644; P:vagus nerve morphogenesis; IEA:Ensembl.
//
ID   PLXB1_HUMAN             Reviewed;        2135 AA.
AC   O43157; A6H8Y2; Q6NY20; Q9UIV7; Q9UJ92; Q9UJ93;
DE   RecName: Full=Plexin-B1;
DE   AltName: Full=Semaphorin receptor SEP;
DE   Flags: Precursor;
GN   Name=PLXNB1; Synonyms=KIAA0407, PLXN5, SEP;
DR   GO; GO:0032794; F:GTPase activating protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0017154; F:semaphorin receptor activity; IDA:UniProtKB.
DR   GO; GO:0030215; F:semaphorin receptor binding; TAS:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0043931; P:ossification involved in bone maturation; ISS:BHF-UCL.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; IDA:UniProtKB.
DR   GO; GO:1900220; P:semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PLXB2_HUMAN             Reviewed;        1838 AA.
AC   O15031; A6QRH0; Q7KZU3; Q9BSU7;
DE   RecName: Full=Plexin-B2;
DE   AltName: Full=MM1;
DE   Flags: Precursor;
GN   Name=PLXNB2; Synonyms=KIAA0315;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017154; F:semaphorin receptor activity; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:2001222; P:regulation of neuron migration; ISS:UniProtKB.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
//
ID   PLXB3_HUMAN             Reviewed;        1909 AA.
AC   Q9ULL4; B7Z3E6; F5H773; Q9HDA4;
DE   RecName: Full=Plexin-B3;
DE   Flags: Precursor;
GN   Name=PLXNB3; Synonyms=KIAA1206, PLXN6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IMP:UniProtKB.
DR   GO; GO:0010593; P:negative regulation of lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PLXC1_HUMAN             Reviewed;        1568 AA.
AC   O60486; Q59H25;
DE   RecName: Full=Plexin-C1;
DE   AltName: Full=Virus-encoded semaphorin protein receptor;
DE   AltName: CD_antigen=CD232;
DE   Flags: Precursor;
GN   Name=PLXNC1; Synonyms=VESPR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PLXD1_HUMAN             Reviewed;        1925 AA.
AC   Q9Y4D7; A7E2C6; C9JPZ6; Q6PJS9; Q8IZJ2; Q9BTQ2;
DE   RecName: Full=Plexin-D1;
DE   Flags: Precursor;
GN   Name=PLXND1; Synonyms=KIAA0620;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017154; F:semaphorin receptor activity; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060666; P:dichotomous subdivision of terminal units involved in salivary gland branching; IEA:Ensembl.
DR   GO; GO:0043542; P:endothelial cell migration; ISS:UniProtKB.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007416; P:synapse assembly; ISS:UniProtKB.
//
ID   PM2P3_HUMAN             Reviewed;         168 AA.
AC   Q13401; A6NG70; Q3MJ29;
DE   RecName: Full=Putative postmeiotic segregation increased 2-like protein 3;
DE   AltName: Full=PMS2-related protein 3;
DE   AltName: Full=Postmeiotic segregation increased 2-like protein 9;
DE   AltName: Full=Postmeiotic segregation increased protein 5;
DE   AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 3;
GN   Name=PMS2P3; Synonyms=PMS2L3, PMS2L9, PMS5, PMSR3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   PM2P2_HUMAN             Reviewed;         297 AA.
AC   O95744;
DE   RecName: Full=Putative postmeiotic segregation increased 2-like protein 2;
DE   AltName: Full=Postmeiotic segregation increased 2-like protein 14;
DE   AltName: Full=Postmeiotic segregation increased protein 4;
DE   AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 2;
GN   Name=PMS2P2; Synonyms=PMS2L14, PMS2L2, PMS4;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006298; P:mismatch repair; IBA:RefGenome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
//
ID   PM34_HUMAN              Reviewed;         307 AA.
AC   O43808; A8KA59; Q5TFL0; Q9UGW8; Q9UGY7;
DE   RecName: Full=Peroxisomal membrane protein PMP34;
DE   AltName: Full=34 kDa peroxisomal membrane protein;
DE   AltName: Full=Solute carrier family 25 member 17;
GN   Name=SLC25A17; Synonyms=PMP34;
DR   GO; GO:0015217; F:ADP transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0080122; F:AMP transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005347; F:ATP transmembrane transporter activity; IGI:BHF-UCL.
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0015228; F:coenzyme A transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015230; F:FAD transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0044610; F:FMN transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0051724; F:NAD transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015866; P:ADP transport; IDA:GOC.
DR   GO; GO:0080121; P:AMP transport; IDA:GOC.
DR   GO; GO:0015867; P:ATP transport; IGI:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0035349; P:coenzyme A transmembrane transport; IDA:GOC.
DR   GO; GO:0035350; P:FAD transmembrane transport; IDA:GOC.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IGI:BHF-UCL.
DR   GO; GO:0015908; P:fatty acid transport; IGI:BHF-UCL.
DR   GO; GO:0043132; P:NAD transport; IDA:GOC.
DR   GO; GO:1901679; P:nucleotide transmembrane transport; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PM2P1_HUMAN             Reviewed;         440 AA.
AC   A4D2B8; Q0VGD2; Q13400; Q16530; Q6NVZ2; Q7KZ90;
DE   RecName: Full=Putative postmeiotic segregation increased 2-like protein 1;
DE   AltName: Full=PMS2-related protein 2;
DE   AltName: Full=Postmeiotic segregation increased 2-like protein 13;
DE   AltName: Full=Postmeiotic segregation increased 2-like protein 6;
DE   AltName: Full=Postmeiotic segregation increased 2-like protein 8;
DE   AltName: Full=Postmeiotic segregation increased protein 3;
DE            Short=hPMS3;
DE   AltName: Full=Postmeiotic segregation increased protein 8;
DE   AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 1;
GN   Name=PMS2P1;
GN   Synonyms=PMS2L1, PMS2L13, PMS2L6, PMS2L8, PMS3, PMS8, PMSR2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006298; P:mismatch repair; IBA:RefGenome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
//
ID   PM2P5_HUMAN             Reviewed;         134 AA.
AC   A8MQ11;
DE   RecName: Full=Postmeiotic segregation increased 2-like protein 5;
DE   AltName: Full=Postmeiotic segregation increased protein 4;
DE   AltName: Full=Postmeiotic segregation increased protein 7;
DE   AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 5;
GN   Name=PMS2P5; Synonyms=PMS2L5, PMS4, PMS7;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006298; P:mismatch repair; IBA:RefGenome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
//
ID   PM2PB_HUMAN             Reviewed;         270 AA.
AC   Q13670;
DE   RecName: Full=Putative postmeiotic segregation increased 2-like protein 11;
DE   AltName: Full=PMS2-related protein 6;
DE   AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 11;
GN   Name=PMS2P11; Synonyms=PMS2L11, PMSR6;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006298; P:mismatch repair; IBA:RefGenome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
//
ID   PMEL_HUMAN              Reviewed;         661 AA.
AC   P40967; B3KS57; B7Z6D7; Q12763; Q14448; Q14817; Q16565;
DE   RecName: Full=Melanocyte protein PMEL;
DE   AltName: Full=ME20-M;
DE            Short=ME20M;
DE   AltName: Full=Melanocyte protein Pmel 17;
DE   AltName: Full=Melanocytes lineage-specific antigen GP100;
DE   AltName: Full=Melanoma-associated ME20 antigen;
DE   AltName: Full=P1;
DE   AltName: Full=P100;
DE   AltName: Full=Premelanosome protein;
DE   AltName: Full=Silver locus protein homolog;
DE   Contains:
DE     RecName: Full=M-alpha;
DE     AltName: Full=95 kDa melanocyte-specific secreted glycoprotein;
DE     AltName: Full=P26;
DE     AltName: Full=Secreted melanoma-associated ME20 antigen;
DE              Short=ME20-S;
DE              Short=ME20S;
DE   Contains:
DE     RecName: Full=M-beta;
DE   Flags: Precursor;
GN   Name=PMEL; Synonyms=D12S53E, PMEL17, SILV;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0032438; P:melanosome organization; IDA:UniProtKB.
//
ID   PMEPA_HUMAN             Reviewed;         287 AA.
AC   Q969W9; Q5TDR6; Q8NER4; Q96B72; Q9UJD3;
DE   RecName: Full=Transmembrane prostate androgen-induced protein;
DE   AltName: Full=Solid tumor-associated 1 protein;
GN   Name=PMEPA1; Synonyms=STAG1, TMEPAI;
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   PMF1_HUMAN              Reviewed;         205 AA.
AC   Q6P1K2; A8K0C5; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9;
AC   Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3;
DE   RecName: Full=Polyamine-modulated factor 1;
DE            Short=PMF-1;
GN   Name=PMF1;
DR   GO; GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PMFBP_HUMAN             Reviewed;        1022 AA.
AC   Q8TBY8; B3KVI9; H7BY07; Q8NA09; Q9BY16; Q9H0H4;
DE   RecName: Full=Polyamine-modulated factor 1-binding protein 1;
DE            Short=PMF-1-binding protein;
GN   Name=PMFBP1;
//
ID   PMGE_HUMAN              Reviewed;         259 AA.
AC   P07738; A4D1N9;
DE   RecName: Full=Bisphosphoglycerate mutase;
DE            Short=BPGM;
DE            EC=5.4.2.4;
DE   AltName: Full=2,3-bisphosphoglycerate mutase, erythrocyte;
DE   AltName: Full=2,3-bisphosphoglycerate synthase;
DE            EC=3.1.3.13;
DE            EC=5.4.2.11;
DE   AltName: Full=2,3-diphosphoglycerate mutase;
DE            Short=DPGM;
DE   AltName: Full=BPG-dependent PGAM;
GN   Name=BPGM;
DR   GO; GO:0004083; F:bisphosphoglycerate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004082; F:bisphosphoglycerate mutase activity; TAS:ProtInc.
DR   GO; GO:0004619; F:phosphoglycerate mutase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; NAS:ProtInc.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
//
ID   PMGT1_HUMAN             Reviewed;         660 AA.
AC   Q8WZA1; D3DQ16; Q5VST2; Q5VST3; Q9BV55; Q9H9L8; Q9NXF9; Q9NYF7;
DE   RecName: Full=Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1;
DE            Short=POMGnT1;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2;
DE            Short=GnT I.2;
GN   Name=POMGNT1; Synonyms=MGAT1.2; ORFNames=UNQ746/PRO1475;
DR   GO; GO:0047223; F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; IDA:MGI.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:MGI.
//
ID   PMGT2_HUMAN             Reviewed;         580 AA.
AC   Q8NAT1; B3KWC3; Q96SY3;
DE   RecName: Full=Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2;
DE            Short=POMGnT2;
DE            EC=2.4.1.-;
DE   AltName: Full=Extracellular O-linked N-acetylglucosamine transferase-like;
DE   AltName: Full=Glycosyltransferase-like domain-containing protein 2;
GN   Name=POMGNT2; Synonyms=AGO61, C3orf39, EOGTL, GTDC2;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0097363; F:protein O-GlcNAc transferase activity; IDA:MGI.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
//
ID   PML_HUMAN               Reviewed;         882 AA.
AC   P29590; E9PBR7; P29591; P29592; P29593; Q00755; Q15959; Q59FP9;
AC   Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9;
AC   Q9BZY0; Q9BZY2; Q9BZY3;
DE   RecName: Full=Protein PML;
DE   AltName: Full=Promyelocytic leukemia protein;
DE   AltName: Full=RING finger protein 71;
DE   AltName: Full=Tripartite motif-containing protein 19;
GN   Name=PML; Synonyms=MYL, PP8675, RNF71, TRIM19;
DR   GO; GO:0050897; F:cobalt ion binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0032183; F:SUMO binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0090398; P:cellular senescence; IDA:UniProtKB.
DR   GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; ISS:UniProtKB.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; ISS:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:MGI.
DR   GO; GO:0030099; P:myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:2000059; P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IMP:UniProtKB.
DR   GO; GO:0032211; P:negative regulation of telomere maintenance via telomerase; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032938; P:negative regulation of translation in response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0030578; P:PML body organization; IDA:UniProtKB.
DR   GO; GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IDA:UniProtKB.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IDA:UniProtKB.
DR   GO; GO:0010522; P:regulation of calcium ion transport into cytosol; ISS:UniProtKB.
DR   GO; GO:2000779; P:regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0045343; P:regulation of MHC class I biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PMM2_HUMAN              Reviewed;         246 AA.
AC   O15305; A8K672; D3DUF3;
DE   RecName: Full=Phosphomannomutase 2;
DE            Short=PMM 2;
DE            EC=5.4.2.8;
GN   Name=PMM2;
DR   GO; GO:0004615; F:phosphomannomutase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.
DR   GO; GO:0019307; P:mannose biosynthetic process; IEA:InterPro.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   PMM1_HUMAN              Reviewed;         262 AA.
AC   Q92871; A8K003; Q92586;
DE   RecName: Full=Phosphomannomutase 1;
DE            Short=PMM 1;
DE            EC=5.4.2.8;
DE   AltName: Full=PMMH-22;
GN   Name=PMM1; Synonyms=PMMH22;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004615; F:phosphomannomutase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0009298; P:GDP-mannose biosynthetic process; TAS:Reactome.
DR   GO; GO:0019307; P:mannose biosynthetic process; IEA:InterPro.
DR   GO; GO:0006013; P:mannose metabolic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   PMP22_HUMAN             Reviewed;         160 AA.
AC   Q01453; Q8WV01;
DE   RecName: Full=Peripheral myelin protein 22;
DE            Short=PMP-22;
DE   AltName: Full=Growth arrest-specific protein 3;
DE            Short=GAS-3;
GN   Name=PMP22; Synonyms=GAS3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0032288; P:myelin assembly; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   PMS2L_HUMAN             Reviewed;         193 AA.
AC   Q68D20; B4DK88; Q764P1;
DE   RecName: Full=Protein PMS2CL;
DE   AltName: Full=PMS2-C terminal-like protein;
GN   Name=PMS2CL;
//
ID   PMS1_HUMAN              Reviewed;         932 AA.
AC   P54277; D3DPI1; Q4VAL4; Q5FBZ3; Q5FBZ6; Q5FBZ8;
DE   RecName: Full=PMS1 protein homolog 1;
DE   AltName: Full=DNA mismatch repair protein PMS1;
GN   Name=PMS1; Synonyms=PMSL1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0032407; F:MutSalpha complex binding; IBA:RefGenome.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006298; P:mismatch repair; IBA:RefGenome.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   PMS2_HUMAN              Reviewed;         862 AA.
AC   P54278; B2R610; Q52LH6; Q5FBW9; Q5FBX1; Q5FBX2; Q75MR2;
DE   RecName: Full=Mismatch repair endonuclease PMS2;
DE            EC=3.1.-.-;
DE   AltName: Full=DNA mismatch repair protein PMS2;
DE   AltName: Full=PMS1 protein homolog 2;
GN   Name=PMS2; Synonyms=PMSL2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; IDA:HGNC.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032138; F:single base insertion or deletion binding; IDA:HGNC.
DR   GO; GO:0006200; P:ATP catabolic process; IBA:GOC.
DR   GO; GO:0006298; P:mismatch repair; IDA:HGNC.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.
DR   GO; GO:0016447; P:somatic recombination of immunoglobulin gene segments; IEA:Ensembl.
//
ID   PMVK_HUMAN              Reviewed;         192 AA.
AC   Q15126; Q5TZW9;
DE   RecName: Full=Phosphomevalonate kinase;
DE            Short=PMKase;
DE            Short=hPMK;
DE            EC=2.7.4.2;
GN   Name=PMVK; Synonyms=PMKI;
DR   GuidetoPHARMACOLOGY; 641; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004631; F:phosphomevalonate kinase activity; IDA:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0019287; P:isopentenyl diphosphate biosynthetic process, mevalonate pathway; IEA:UniProtKB-UniPathway.
DR   GO; GO:0070723; P:response to cholesterol; IEP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016126; P:sterol biosynthetic process; IDA:UniProtKB.
//
ID   PMYT1_HUMAN             Reviewed;         499 AA.
AC   Q99640; B3KUN8; B4DXD4; D3DUA4; F8W164; I3L1V2; O14731; Q7LE24;
AC   Q8TCM9;
DE   RecName: Full=Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Myt1 kinase;
GN   Name=PKMYT1; Synonyms=MYT1;
DR   GuidetoPHARMACOLOGY; 2167; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0007088; P:regulation of mitosis; TAS:ProtInc.
//
ID   PN6BL_HUMAN             Reviewed;         334 AA.
AC   A8MUQ0;
DE   RecName: Full=Putative paraneoplastic antigen-like protein 6B-like protein LOC649238;
//
ID   PNCB_HUMAN              Reviewed;         538 AA.
AC   Q6XQN6; A7BFI3; Q6PJL1; Q6XQN4; Q6XQN5; Q8N5E8; Q9BRG0;
DE   RecName: Full=Nicotinate phosphoribosyltransferase;
DE            Short=NAPRTase;
DE            EC=6.3.4.21;
DE   AltName: Full=FHA-HIT-interacting protein;
DE   AltName: Full=Nicotinate phosphoribosyltransferase domain-containing protein 1;
GN   Name=NAPRT1; Synonyms=FHIP;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004516; F:nicotinate phosphoribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019674; P:NAD metabolic process; TAS:Reactome.
DR   GO; GO:0006769; P:nicotinamide metabolic process; TAS:Reactome.
DR   GO; GO:0019358; P:nicotinate nucleotide salvage; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PNDC1_HUMAN             Reviewed;         520 AA.
AC   Q8NA58; Q5TAP7; Q8N7X5;
DE   RecName: Full=Poly(A)-specific ribonuclease PARN-like domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=PNLDC1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   PNEU_HUMAN              Reviewed;          10 AA.
AC   P22103;
DE   RecName: Full=Pneumadin;
DE            Short=PNM;
DR   GO; GO:0030103; P:vasopressin secretion; NAS:UniProtKB.
//
ID   PNKD_HUMAN              Reviewed;         385 AA.
AC   Q8N490; A8K1F2; Q96A48; Q9BU26; Q9NSX4; Q9ULN6; Q9Y4T1;
DE   RecName: Full=Probable hydrolase PNKD;
DE            EC=3.-.-.-;
DE   AltName: Full=Myofibrillogenesis regulator 1;
DE            Short=MR-1;
DE   AltName: Full=Paroxysmal nonkinesiogenic dyskinesia protein;
DE   AltName: Full=Trans-activated by hepatitis C virus core protein 2;
GN   Name=PNKD; Synonyms=KIAA1184, MR1, TAHCCP2;
GN   ORFNames=FKSG19, UNQ2491/PRO5778;
DR   GO; GO:0004416; F:hydroxyacylglutathione hydrolase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006750; P:glutathione biosynthetic process; IEA:InterPro.
//
ID   PNKP_HUMAN              Reviewed;         521 AA.
AC   Q96T60; Q9P1V2; Q9UKU8; Q9UNF8; Q9UNI0;
DE   RecName: Full=Bifunctional polynucleotide phosphatase/kinase;
DE   AltName: Full=DNA 5'-kinase/3'-phosphatase;
DE   AltName: Full=Polynucleotide kinase-3'-phosphatase;
DE   Includes:
DE     RecName: Full=Polynucleotide 3'-phosphatase;
DE              EC=3.1.3.32;
DE     AltName: Full=2'(3')-polynucleotidase;
DE   Includes:
DE     RecName: Full=Polynucleotide 5'-hydroxyl-kinase;
DE              EC=2.7.1.78;
GN   Name=PNKP;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0046404; F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; NAS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; NAS:UniProtKB.
DR   GO; GO:0019201; F:nucleotide kinase activity; IDA:UniProtKB.
DR   GO; GO:0046403; F:polynucleotide 3'-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017076; F:purine nucleotide binding; NAS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IGI:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; NAS:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; NAS:GOC.
DR   GO; GO:0046939; P:nucleotide phosphorylation; IDA:UniProtKB.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; NAS:UniProtKB.
DR   GO; GO:0098506; P:polynucleotide 3' dephosphorylation; IDA:GOC.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; NAS:UniProtKB.
//
ID   PNISR_HUMAN             Reviewed;         805 AA.
AC   Q8TF01; A8K540; E1P5D2; Q5T064; Q5T065; Q6P2B4; Q6P2N4; Q6PJ93;
AC   Q6PK36; Q7Z640; Q8N2L1; Q8TF00; Q96K10; Q96SI3; Q96SM5; Q9P076;
AC   Q9P0C0; Q9Y4N3;
DE   RecName: Full=Arginine/serine-rich protein PNISR;
DE   AltName: Full=PNN-interacting serine/arginine-rich protein;
DE   AltName: Full=SR-related protein;
DE   AltName: Full=SR-rich protein;
DE   AltName: Full=Serine/arginine-rich-splicing regulatory protein 130;
DE            Short=SRrp130;
DE   AltName: Full=Splicing factor, arginine/serine-rich 130;
DE   AltName: Full=Splicing factor, arginine/serine-rich 18;
GN   Name=PNISR; Synonyms=C6orf111, SFRS18, SRRP130;
GN   ORFNames=HSPC261, HSPC306;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   PNM6A_HUMAN             Reviewed;         399 AA.
AC   P0CW24; A8K1G4; D3DWT8; Q96A40;
DE   RecName: Full=Paraneoplastic antigen-like protein 6A;
GN   Name=PNMA6A;
//
ID   PNM6B_HUMAN             Reviewed;         399 AA.
AC   P0C5W0;
DE   RecName: Full=Paraneoplastic antigen-like protein 6B;
GN   Name=PNMA6B;
//
ID   PNM6D_HUMAN             Reviewed;         399 AA.
AC   P0CZ20;
DE   RecName: Full=Paraneoplastic antigen-like protein 6D;
GN   Name=PNMA6D;
//
ID   PNMA2_HUMAN             Reviewed;         364 AA.
AC   Q9UL42; B3KNY9; O94959; O95145; Q49A18; Q9UL43;
DE   RecName: Full=Paraneoplastic antigen Ma2;
DE   AltName: Full=40 kDa neuronal protein;
DE   AltName: Full=Onconeuronal antigen Ma2;
DE   AltName: Full=Paraneoplastic neuronal antigen MM2;
GN   Name=PNMA2; Synonyms=KIAA0883, MA2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
//
ID   PNMA3_HUMAN             Reviewed;         463 AA.
AC   Q9UL41; D3DWT7; Q9H0A4;
DE   RecName: Full=Paraneoplastic antigen Ma3;
GN   Name=PNMA3; Synonyms=MA3;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
//
ID   PNMA1_HUMAN             Reviewed;         353 AA.
AC   Q8ND90; A8K4L5; O95144; Q8NG07;
DE   RecName: Full=Paraneoplastic antigen Ma1;
DE   AltName: Full=37 kDa neuronal protein;
DE   AltName: Full=Neuron- and testis-specific protein 1;
GN   Name=PNMA1; Synonyms=MA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
//
ID   PNMA5_HUMAN             Reviewed;         448 AA.
AC   Q96PV4; B4DI72; B7Z9Y9; Q495L5; Q8NET3;
DE   RecName: Full=Paraneoplastic antigen-like protein 5;
DE   AltName: Full=Tumor antigen BJ-HCC-25;
GN   Name=PNMA5; Synonyms=KIAA1934;
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
//
ID   PNML1_HUMAN             Reviewed;         439 AA.
AC   Q86V59; A8K2F3; Q5U638; Q8N3H4; Q9NVE8;
DE   RecName: Full=PNMA-like protein 1;
GN   Name=PNMAL1;
//
ID   PNML2_HUMAN             Reviewed;         279 AA.
AC   Q9ULN7; C9JGD5; Q08E79; Q0D2F9; Q6ZVD1;
DE   RecName: Full=PNMA-like protein 2;
GN   Name=PNMAL2; Synonyms=KIAA1183;
//
ID   PNM6C_HUMAN             Reviewed;         399 AA.
AC   P0CW26; A8K1G4; D3DWT8; Q96A40;
DE   RecName: Full=Paraneoplastic antigen-like protein 6C;
GN   Name=PNMA6C;
//
ID   PNMT_HUMAN              Reviewed;         282 AA.
AC   P11086;
DE   RecName: Full=Phenylethanolamine N-methyltransferase;
DE            Short=PNMTase;
DE            EC=2.1.1.28;
DE   AltName: Full=Noradrenaline N-methyltransferase;
GN   Name=PNMT; Synonyms=PENT;
DR   GuidetoPHARMACOLOGY; 2496; -.
DR   GO; GO:0004603; F:phenylethanolamine N-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0042423; P:catecholamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0042418; P:epinephrine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PNO1_HUMAN              Reviewed;         252 AA.
AC   Q9NRX1; A8K6Q0; Q53G13; Q8WVB8;
DE   RecName: Full=RNA-binding protein PNO1;
GN   Name=PNO1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   PNOC_HUMAN              Reviewed;         176 AA.
AC   Q13519; Q6FH16;
DE   RecName: Full=Prepronociceptin;
DE   Contains:
DE     RecName: Full=Neuropeptide 1;
DE   Contains:
DE     RecName: Full=Nociceptin;
DE     AltName: Full=Orphanin FQ;
DE     AltName: Full=PPNOC;
DE   Contains:
DE     RecName: Full=Neuropeptide 2;
DE   Flags: Precursor;
GN   Name=PNOC; Synonyms=OFQ;
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; IEA:UniProtKB-KW.
//
ID   PNPH_HUMAN              Reviewed;         289 AA.
AC   P00491; B2R8S5; D3DS00; Q15160; Q5PZ03;
DE   RecName: Full=Purine nucleoside phosphorylase;
DE            Short=PNP;
DE            EC=2.4.2.1;
DE   AltName: Full=Inosine phosphorylase;
DE   AltName: Full=Inosine-guanosine phosphorylase;
GN   Name=PNP; Synonyms=NP;
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0001882; F:nucleoside binding; IDA:UniProtKB.
DR   GO; GO:0042301; F:phosphate ion binding; IDA:UniProtKB.
DR   GO; GO:0002060; F:purine nucleobase binding; IDA:UniProtKB.
DR   GO; GO:0004731; F:purine-nucleoside phosphorylase activity; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IMP:UniProtKB.
DR   GO; GO:0006148; P:inosine catabolic process; IDA:MGI.
DR   GO; GO:0070970; P:interleukin-2 secretion; IMP:UniProtKB.
DR   GO; GO:0034356; P:NAD biosynthesis via nicotinamide riboside salvage pathway; IGI:UniProtKB.
DR   GO; GO:0006738; P:nicotinamide riboside catabolic process; IDA:UniProtKB.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IDA:UniProtKB.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IDA:MGI.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:MGI.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0043101; P:purine-containing compound salvage; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034418; P:urate biosynthetic process; IDA:MGI.
//
ID   PNPO_HUMAN              Reviewed;         261 AA.
AC   Q9NVS9; D3DTT9;
DE   RecName: Full=Pyridoxine-5'-phosphate oxidase;
DE            EC=1.4.3.5;
DE   AltName: Full=Pyridoxamine-phosphate oxidase;
GN   Name=PNPO;
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0004733; F:pyridoxamine-phosphate oxidase activity; TAS:Reactome.
DR   GO; GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042816; P:vitamin B6 metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PNPT1_HUMAN             Reviewed;         783 AA.
AC   Q8TCS8; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q96T05; Q9BRU3; Q9BVX0;
DE   RecName: Full=Polyribonucleotide nucleotidyltransferase 1, mitochondrial;
DE            EC=2.7.7.8;
DE   AltName: Full=3'-5' RNA exonuclease OLD35;
DE   AltName: Full=PNPase old-35;
DE   AltName: Full=Polynucleotide phosphorylase 1;
DE            Short=PNPase 1;
DE   AltName: Full=Polynucleotide phosphorylase-like protein;
DE   Flags: Precursor;
GN   Name=PNPT1; Synonyms=PNPASE;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0035198; F:miRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0034046; F:poly(G) binding; IDA:UniProtKB.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004654; F:polyribonucleotide nucleotidyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IDA:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0000958; P:mitochondrial mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0097222; P:mitochondrial mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0000965; P:mitochondrial RNA 3'-end processing; IMP:UniProtKB.
DR   GO; GO:0000964; P:mitochondrial RNA 5'-end processing; IMP:UniProtKB.
DR   GO; GO:0000957; P:mitochondrial RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; ISS:UniProtKB.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0045926; P:negative regulation of growth; IDA:UniProtKB.
DR   GO; GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:2000627; P:positive regulation of miRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0061014; P:positive regulation of mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; IDA:UniProtKB.
DR   GO; GO:0043457; P:regulation of cellular respiration; ISS:UniProtKB.
DR   GO; GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0035927; P:RNA import into mitochondrion; IDA:UniProtKB.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0043631; P:RNA polyadenylation; IDA:UniProtKB.
DR   GO; GO:0035928; P:rRNA import into mitochondrion; IDA:UniProtKB.
//
ID   PNRC1_HUMAN             Reviewed;         327 AA.
AC   Q12796; B2R6Q0; E1P515; Q5T7J6;
DE   RecName: Full=Proline-rich nuclear receptor coactivator 1;
DE   AltName: Full=Proline-rich protein 2;
DE   AltName: Full=Protein B4-2;
GN   Name=PNRC1; Synonyms=PROL2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PNRC2_HUMAN             Reviewed;         139 AA.
AC   Q9NPJ4; B4DU72;
DE   RecName: Full=Proline-rich nuclear receptor coactivator 2;
GN   Name=PNRC2; ORFNames=HSPC208;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; TAS:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PO210_HUMAN             Reviewed;        1887 AA.
AC   Q8TEM1; A6NN56; O94980; Q6NXG6; Q8NBJ1; Q9H6C8; Q9UFP3;
DE   RecName: Full=Nuclear pore membrane glycoprotein 210;
DE            Short=Nuclear pore protein gp210;
DE   AltName: Full=Nuclear envelope pore membrane protein POM 210;
DE            Short=POM210;
DE   AltName: Full=Nucleoporin Nup210;
DE   AltName: Full=Pore membrane protein of 210 kDa;
DE   Flags: Precursor;
GN   Name=NUP210; Synonyms=KIAA0906; ORFNames=PSEC0245;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PO2F1_HUMAN             Reviewed;         743 AA.
AC   P14859; B1AL91; B1AL93; B4E029; J3KP77; Q5TBT7; Q6PK46; Q8NEU9;
AC   Q9BPV1;
DE   RecName: Full=POU domain, class 2, transcription factor 1;
DE   AltName: Full=NF-A1;
DE   AltName: Full=Octamer-binding protein 1;
DE            Short=Oct-1;
DE   AltName: Full=Octamer-binding transcription factor 1;
DE            Short=OTF-1;
GN   Name=POU2F1; Synonyms=OCT1, OTF1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030910; P:olfactory placode formation; IEA:Ensembl.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   PO2F2_HUMAN             Reviewed;         479 AA.
AC   P09086; Q16648; Q7M4M8; Q9BRS4;
DE   RecName: Full=POU domain, class 2, transcription factor 2;
DE   AltName: Full=Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2;
DE   AltName: Full=Octamer-binding protein 2;
DE            Short=Oct-2;
DE   AltName: Full=Octamer-binding transcription factor 2;
DE            Short=OTF-2;
GN   Name=POU2F2; Synonyms=OCT2, OTF2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0002380; P:immunoglobulin secretion involved in immune response; IEA:Ensembl.
DR   GO; GO:0002335; P:mature B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PO2F3_HUMAN             Reviewed;         436 AA.
AC   Q9UKI9; A8K7H8; B4DY07; F5GWW6; Q3MIY3; Q9UKR7; Q9Y504;
DE   RecName: Full=POU domain, class 2, transcription factor 3;
DE   AltName: Full=Octamer-binding protein 11;
DE            Short=Oct-11;
DE   AltName: Full=Octamer-binding transcription factor 11;
DE            Short=OTF-11;
DE   AltName: Full=Transcription factor PLA-1;
DE   AltName: Full=Transcription factor Skn-1;
GN   Name=POU2F3; Synonyms=OTF11, PLA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   PO3F1_HUMAN             Reviewed;         451 AA.
AC   Q03052; Q5TAG2;
DE   RecName: Full=POU domain, class 3, transcription factor 1;
DE   AltName: Full=Octamer-binding protein 6;
DE            Short=Oct-6;
DE   AltName: Full=Octamer-binding transcription factor 6;
DE            Short=OTF-6;
DE   AltName: Full=POU domain transcription factor SCIP;
GN   Name=POU3F1; Synonyms=OCT6, OTF6;
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008366; P:axon ensheathment; TAS:ProtInc.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
//
ID   PO3F2_HUMAN             Reviewed;         443 AA.
AC   P20265; Q14960; Q86V54; Q9UJL0;
DE   RecName: Full=POU domain, class 3, transcription factor 2;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 2;
DE            Short=Brain-2;
DE            Short=Brn-2;
DE   AltName: Full=Nervous system-specific octamer-binding transcription factor N-Oct-3;
DE   AltName: Full=Octamer-binding protein 7;
DE            Short=Oct-7;
DE   AltName: Full=Octamer-binding transcription factor 7;
DE            Short=OTF-7;
GN   Name=POU3F2; Synonyms=BRN2, OCT7, OTF7;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0014002; P:astrocyte development; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0021869; P:forebrain ventricular zone progenitor cell division; IEA:Ensembl.
DR   GO; GO:0021979; P:hypothalamus cell differentiation; IEA:Ensembl.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; IEA:Ensembl.
DR   GO; GO:0021985; P:neurohypophysis development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; IEA:Ensembl.
//
ID   PO3F3_HUMAN             Reviewed;         500 AA.
AC   P20264; P78379; Q4ZG25;
DE   RecName: Full=POU domain, class 3, transcription factor 3;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 1;
DE            Short=Brain-1;
DE            Short=Brn-1;
DE   AltName: Full=Octamer-binding protein 8;
DE            Short=Oct-8;
DE   AltName: Full=Octamer-binding transcription factor 8;
DE            Short=OTF-8;
GN   Name=POU3F3; Synonyms=BRN1, OTF8;
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl.
DR   GO; GO:0021869; P:forebrain ventricular zone progenitor cell division; IEA:Ensembl.
DR   GO; GO:0072218; P:metanephric ascending thin limb development; ISS:UniProtKB.
DR   GO; GO:0072240; P:metanephric DCT cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072236; P:metanephric loop of Henle development; ISS:UniProtKB.
DR   GO; GO:0072227; P:metanephric macula densa development; ISS:UniProtKB.
DR   GO; GO:0072233; P:metanephric thick ascending limb development; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PO3F4_HUMAN             Reviewed;         361 AA.
AC   P49335; B2RC71; Q5H9G9; Q99410;
DE   RecName: Full=POU domain, class 3, transcription factor 4;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 4;
DE            Short=Brain-4;
DE            Short=Brn-4;
DE   AltName: Full=Octamer-binding protein 9;
DE            Short=Oct-9;
DE   AltName: Full=Octamer-binding transcription factor 9;
DE            Short=OTF-9;
GN   Name=POU3F4; Synonyms=BRN4, OTF9;
DR   GO; GO:0003680; F:AT DNA binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   PO4F1_HUMAN             Reviewed;         419 AA.
AC   Q01851; Q14986; Q15318; Q5T227;
DE   RecName: Full=POU domain, class 4, transcription factor 1;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 3A;
DE            Short=Brain-3A;
DE            Short=Brn-3A;
DE   AltName: Full=Homeobox/POU domain protein RDC-1;
DE   AltName: Full=Oct-T1;
GN   Name=POU4F1; Synonyms=BRN3A, RDC1;
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0007409; P:axonogenesis; TAS:BHF-UCL.
DR   GO; GO:0021535; P:cell migration in hindbrain; IEA:Ensembl.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021986; P:habenula development; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; TAS:BHF-UCL.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; TAS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0048665; P:neuron fate specification; ISS:BHF-UCL.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; ISS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0051355; P:proprioception involved in equilibrioception; IEA:Ensembl.
DR   GO; GO:0050767; P:regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0048880; P:sensory system development; ISS:BHF-UCL.
DR   GO; GO:0001967; P:suckling behavior; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:GOC.
DR   GO; GO:0021559; P:trigeminal nerve development; ISS:BHF-UCL.
DR   GO; GO:0003223; P:ventricular compact myocardium morphogenesis; IEA:Ensembl.
//
ID   PO4F2_HUMAN             Reviewed;         409 AA.
AC   Q12837; B1PJR6; B2RC84; Q13883; Q14987;
DE   RecName: Full=POU domain, class 4, transcription factor 2;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 3B;
DE            Short=Brain-3B;
DE            Short=Brn-3B;
GN   Name=POU4F2; Synonyms=BRN3B;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   PO4F3_HUMAN             Reviewed;         338 AA.
AC   Q15319; O60557; Q2M3F8;
DE   RecName: Full=POU domain, class 4, transcription factor 3;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 3C;
DE            Short=Brain-3C;
DE            Short=Brn-3C;
GN   Name=POU4F3; Synonyms=BRN3C;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0021562; P:vestibulocochlear nerve development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PO5F1_HUMAN             Reviewed;         360 AA.
AC   Q01860; A6NCS1; A6NLL8; D2IYK4; P31359; Q15167; Q15168; Q16422;
AC   Q5STF3; Q5STF4;
DE   RecName: Full=POU domain, class 5, transcription factor 1;
DE   AltName: Full=Octamer-binding protein 3;
DE            Short=Oct-3;
DE   AltName: Full=Octamer-binding protein 4;
DE            Short=Oct-4;
DE   AltName: Full=Octamer-binding transcription factor 3;
DE            Short=OTF-3;
GN   Name=POU5F1; Synonyms=OCT3, OCT4, OTF3;
DR   GO; GO:0003677; F:DNA binding; IDA:HGNC.
DR   GO; GO:0035198; F:miRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:HGNC.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001824; P:blastocyst development; ISS:BHF-UCL.
DR   GO; GO:0003130; P:BMP signaling pathway involved in heart induction; IMP:BHF-UCL.
DR   GO; GO:0060913; P:cardiac cell fate determination; IDA:BHF-UCL.
DR   GO; GO:0060795; P:cell fate commitment involved in formation of primary germ layer; IMP:BHF-UCL.
DR   GO; GO:0001714; P:endodermal cell fate specification; IDA:MGI.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0060965; P:negative regulation of gene silencing by miRNA; IMP:UniProtKB.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0009786; P:regulation of asymmetric cell division; ISS:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0090081; P:regulation of heart induction by regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0090308; P:regulation of methylation-dependent chromatin silencing; IDA:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0009611; P:response to wounding; IEP:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   PO5F2_HUMAN             Reviewed;         328 AA.
AC   Q8N7G0; Q15169; Q6MZL7; Q8N748;
DE   RecName: Full=POU domain, class 5, transcription factor 2;
DE   AltName: Full=Sperm 1 POU domain transcription factor;
DE            Short=SPRM-1;
GN   Name=POU5F2; Synonyms=SPRM1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PO6F2_HUMAN             Reviewed;         691 AA.
AC   P78424; A4D1W2; C4AMB9; P78425; Q75ME8; Q86UM6; Q9UDS7;
DE   RecName: Full=POU domain, class 6, transcription factor 2;
DE   AltName: Full=Retina-derived POU domain factor 1;
DE            Short=RPF-1;
GN   Name=POU6F2; Synonyms=RPF1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007402; P:ganglion mother cell fate determination; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PO6F1_HUMAN             Reviewed;         301 AA.
AC   Q14863; Q15944; Q6DK47; Q7Z7P6;
DE   RecName: Full=POU domain, class 6, transcription factor 1;
DE   AltName: Full=Brain-specific homeobox/POU domain protein 5;
DE            Short=Brain-5;
DE            Short=Brn-5;
DE   AltName: Full=mPOU homeobox protein;
GN   Name=POU6F1; Synonyms=BRN5, MPOU, TCFB1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   POC1A_HUMAN             Reviewed;         407 AA.
AC   Q8NBT0; A4FUW4; E9PFC6; Q0VDF8; Q2TAK6; Q96IK6; Q9UFJ8;
DE   RecName: Full=POC1 centriolar protein homolog A;
DE   AltName: Full=Pix2;
DE   AltName: Full=Proteome of centriole protein 1A;
DE   AltName: Full=WD repeat-containing protein 51A;
GN   Name=POC1A; Synonyms=WDR51A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   POC1B_HUMAN             Reviewed;         478 AA.
AC   Q8TC44; G3V1X0;
DE   RecName: Full=POC1 centriolar protein homolog B;
DE   AltName: Full=Pix1;
DE   AltName: Full=Proteome of centriole protein 1B;
DE   AltName: Full=WD repeat-containing protein 51B;
GN   Name=POC1B; Synonyms=WDR51B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
//
ID   POC5_HUMAN              Reviewed;         575 AA.
AC   Q8NA72; B4DJG7; Q494X7; Q494X9; Q6P085;
DE   RecName: Full=Centrosomal protein POC5;
DE   AltName: Full=Protein of centriole 5;
DE            Short=hPOC5;
GN   Name=POC5; Synonyms=C5orf37;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   PODN_HUMAN              Reviewed;         613 AA.
AC   Q7Z5L7; B4DKN5; B4E373; Q5VVZ2; Q5VVZ3; Q6PIR3; Q6UXL8; Q8N641;
DE   RecName: Full=Podocan;
DE   Flags: Precursor;
GN   Name=PODN; Synonyms=SLRR5A; ORFNames=UNQ293/PRO332;
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
//
ID   PODO_HUMAN              Reviewed;         383 AA.
AC   Q9NP85; B1AM32; B1AM33; Q8N6Q5;
DE   RecName: Full=Podocin;
GN   Name=NPHS2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0072249; P:metanephric glomerular visceral epithelial cell development; IEP:UniProtKB.
//
ID   PODXL_HUMAN             Reviewed;         558 AA.
AC   O00592; A6NHX8; Q52LZ7; Q53ER6;
DE   RecName: Full=Podocalyxin;
DE   AltName: Full=GCTM-2 antigen;
DE   AltName: Full=Gp200;
DE   AltName: Full=Podocalyxin-like protein 1;
DE            Short=PC;
DE            Short=PCLP-1;
DE   Flags: Precursor;
GN   Name=PODXL; Synonyms=PCLP, PCLP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0072175; P:epithelial tube formation; ISS:UniProtKB.
DR   GO; GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0033634; P:positive regulation of cell-cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0032534; P:regulation of microvillus assembly; ISS:UniProtKB.
//
ID   POF1B_HUMAN             Reviewed;         589 AA.
AC   Q8WVV4; A8K2U5; Q5H9E9; Q5H9F0; Q8NG12; Q9H5Y2; Q9H738; Q9H744;
DE   RecName: Full=Protein POF1B;
DE   AltName: Full=Premature ovarian failure protein 1B;
GN   Name=POF1B;
//
ID   POGK_HUMAN              Reviewed;         609 AA.
AC   Q9P215; Q5TIJ1; Q8TE07;
DE   RecName: Full=Pogo transposable element with KRAB domain;
GN   Name=POGK; Synonyms=KIAA1513; ORFNames=LST003, SLTP003;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   POGZ_HUMAN              Reviewed;        1410 AA.
AC   Q7Z3K3; B4DTP8; B4DYL9; B7ZBY5; E9PM80; O75049; Q3LIC4; Q5SZS1;
AC   Q5SZS2; Q5SZS3; Q5SZS4; Q8TDZ7; Q9Y4X7;
DE   RecName: Full=Pogo transposable element with ZNF domain;
DE   AltName: Full=Suppressor of hairy wing homolog 5;
DE   AltName: Full=Zinc finger protein 280E;
DE   AltName: Full=Zinc finger protein 635;
GN   Name=POGZ; Synonyms=KIAA0461, SUHW5, ZNF280E, ZNF635;
GN   ORFNames=Nbla00003;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051382; P:kinetochore assembly; IMP:UniProtKB.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:UniProtKB.
//
ID   POK10_HUMAN             Reviewed;        1014 AA.
AC   P10266; P87890; Q14273;
DE   RecName: Full=HERV-K_5q33.3 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K10 Pol protein;
DE   AltName: Full=HERV-K107 Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK17_HUMAN             Reviewed;         954 AA.
AC   P63136;
DE   RecName: Full=HERV-K_11q22.1 provirus ancestral Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK12_HUMAN             Reviewed;        1459 AA.
AC   P63135;
DE   RecName: Full=HERV-K_1q22 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K(III) Pol protein;
DE   AltName: Full=HERV-K102 Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK20_HUMAN             Reviewed;         969 AA.
AC   Q9UQG0; Q6KH06; Q86YP3;
DE   RecName: Full=HERV-K_3q27.3 provirus ancestral Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK2_HUMAN              Reviewed;         956 AA.
AC   Q9BXR3; Q6KH04; Q9BXR4; Q9UKH5; Q9UP31; Q9WIK9; Q9WJR4;
DE   RecName: Full=HERV-K_7p22.1 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K(C7) Pol protein;
DE   AltName: Full=HERV-K(HML-2.HOM) Pol protein;
DE   AltName: Full=HERV-K108 Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
GN   Name=ERVK6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK3_HUMAN              Reviewed;         959 AA.
AC   Q9WJR5; O15312;
DE   RecName: Full=HERV-K_19q12 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K(C19) Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
GN   Name=ERVK6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK4_HUMAN              Reviewed;        1117 AA.
AC   P63128; Q9UKH4;
DE   RecName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein;
DE   AltName: Full=HERV-K(C6) Gag-Pol protein;
DE   AltName: Full=HERV-K109 Gag-Pol protein;
DE   Contains:
DE     RecName: Full=Matrix protein;
DE   Contains:
DE     RecName: Full=Capsid protein;
DE   Contains:
DE     RecName: Full=Nucleocapsid protein;
DE   Contains:
DE     RecName: Full=Protease;
DE              EC=3.4.23.50;
DE     AltName: Full=PR;
DE     AltName: Full=Retropepsin;
DE   Contains:
DE     RecName: Full=Reverse transcriptase/ribonuclease H;
DE              EC=2.7.7.49;
DE              EC=2.7.7.7;
DE              EC=3.1.26.4;
DE     AltName: Full=p66 RT;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046080; P:dUTP metabolic process; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:InterPro.
//
ID   POK5_HUMAN              Reviewed;         956 AA.
AC   P63132;
DE   RecName: Full=HERV-K_19p13.11 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K113 Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POK7_HUMAN              Reviewed;         812 AA.
AC   Q9QC07; Q6QAI9; Q96PI5;
DE   RecName: Full=HERV-K_1q23.3 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K(C1a) Pol protein;
DE   AltName: Full=HERV-K110 Pol protein;
DE   AltName: Full=HERV-K18 Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
//
ID   POK6_HUMAN              Reviewed;         956 AA.
AC   P63133;
DE   RecName: Full=HERV-K_8p23.1 provirus ancestral Pol protein;
DE   AltName: Full=HERV-K115 Pol protein;
DE   Includes:
DE     RecName: Full=Reverse transcriptase;
DE              Short=RT;
DE              EC=2.7.7.49;
DE   Includes:
DE     RecName: Full=Ribonuclease H;
DE              Short=RNase H;
DE              EC=3.1.26.4;
DE   Includes:
DE     RecName: Full=Integrase;
DE              Short=IN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
//
ID   POLH_HUMAN              Reviewed;         713 AA.
AC   Q9Y253; Q7L8E3; Q96BC4; Q9BX13;
DE   RecName: Full=DNA polymerase eta;
DE            EC=2.7.7.7;
DE   AltName: Full=RAD30 homolog A;
DE   AltName: Full=Xeroderma pigmentosum variant type protein;
GN   Name=POLH; Synonyms=RAD30, RAD30A, XPV;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:GOC.
DR   GO; GO:0006301; P:postreplication repair; IEA:Ensembl.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:Ensembl.
DR   GO; GO:0006282; P:regulation of DNA repair; TAS:ProtInc.
DR   GO; GO:0010225; P:response to UV-C; IDA:UniProtKB.
//
ID   POLI_HUMAN              Reviewed;         740 AA.
AC   Q9UNA4; Q8N590; Q9H0S1; Q9NYH6;
DE   RecName: Full=DNA polymerase iota;
DE            EC=2.7.7.7;
DE   AltName: Full=Eta2;
DE   AltName: Full=RAD30 homolog B;
GN   Name=POLI; Synonyms=RAD30B;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:GOC.
//
ID   POLK_HUMAN              Reviewed;         870 AA.
AC   Q9UBT6; B2RBD2; Q5Q9G5; Q5Q9G6; Q5Q9G7; Q5Q9G8; Q86VJ8; Q8IZY0;
AC   Q8IZY1; Q8NB30; Q96L01; Q96Q86; Q96Q87; Q9UHC5;
DE   RecName: Full=DNA polymerase kappa;
DE            EC=2.7.7.7;
DE   AltName: Full=DINB protein;
DE            Short=DINP;
GN   Name=POLK; Synonyms=DINB1;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; TAS:UniProtKB.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; IMP:UniProtKB.
//
ID   POLS2_HUMAN             Reviewed;         855 AA.
AC   Q5K4E3; A8K2P5; B4DW80; B7ZMK8; E7EX56; Q8NBY4;
DE   RecName: Full=Polyserase-2;
DE            EC=3.4.21.-;
DE   AltName: Full=Polyserine protease 2;
DE   AltName: Full=Serine protease 36;
DE   Flags: Precursor;
GN   Name=PRSS36;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:MGI.
//
ID   POMP_HUMAN              Reviewed;         141 AA.
AC   Q9Y244; A5HKJ2; D6MXU3; Q9HB69;
DE   RecName: Full=Proteasome maturation protein;
DE   AltName: Full=Proteassemblin;
DE   AltName: Full=Protein UMP1 homolog;
DE            Short=hUMP1;
DE   AltName: Full=Voltage-gated K channel beta subunit 4.1;
GN   Name=POMP; Synonyms=C13orf12, UMP1;
GN   ORFNames=HSPC014, HSPC036, PNAS-110;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043248; P:proteasome assembly; IMP:UniProtKB.
//
ID   POMT1_HUMAN             Reviewed;         747 AA.
AC   Q9Y6A1; B3KQG0; B4DIF0; Q5JT01; Q5JT06; Q5JT08; Q8NC91; Q8TCA9;
AC   Q9NX32; Q9NX82; Q9UNT2;
DE   RecName: Full=Protein O-mannosyl-transferase 1;
DE            EC=2.4.1.109;
DE   AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 1;
GN   Name=POMT1;
DR   GO; GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000030; F:mannosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0097502; P:mannosylation; TAS:GOC.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006493; P:protein O-linked glycosylation; TAS:ProtInc.
//
ID   POMT2_HUMAN             Reviewed;         750 AA.
AC   Q9UKY4; Q9NSG6; Q9P1W0; Q9P1W2;
DE   RecName: Full=Protein O-mannosyl-transferase 2;
DE            EC=2.4.1.109;
DE   AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 2;
GN   Name=POMT2;
DR   GO; GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   PON1_HUMAN              Reviewed;         355 AA.
AC   P27169; B2RA40; Q16052; Q6B0J6; Q9UCB1;
DE   RecName: Full=Serum paraoxonase/arylesterase 1;
DE            Short=PON 1;
DE            EC=3.1.1.2;
DE            EC=3.1.1.81;
DE            EC=3.1.8.1;
DE   AltName: Full=Aromatic esterase 1;
DE            Short=A-esterase 1;
DE   AltName: Full=K-45;
DE   AltName: Full=Serum aryldialkylphosphatase 1;
GN   Name=PON1; Synonyms=PON;
DR   GO; GO:0004063; F:aryldialkylphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004064; F:arylesterase activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046395; P:carboxylic acid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0046434; P:organophosphate catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046470; P:phosphatidylcholine metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051099; P:positive regulation of binding; IDA:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0032411; P:positive regulation of transporter activity; IDA:BHF-UCL.
DR   GO; GO:0009605; P:response to external stimulus; NAS:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
//
ID   PON2_HUMAN              Reviewed;         354 AA.
AC   Q15165; A4D1H7; B2RCP9; B4DJD5; O15114; O15115; O75856; Q5FBX7;
AC   Q86YL0;
DE   RecName: Full=Serum paraoxonase/arylesterase 2;
DE            Short=PON 2;
DE            EC=3.1.1.2;
DE            EC=3.1.1.81;
DE   AltName: Full=Aromatic esterase 2;
DE            Short=A-esterase 2;
DE   AltName: Full=Serum aryldialkylphosphatase 2;
GN   Name=PON2;
DR   GO; GO:0004064; F:arylesterase activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
//
ID   PON3_HUMAN              Reviewed;         354 AA.
AC   Q15166; A4D1H8; O75855; O76060; Q6IRU9; Q8IX97; Q9BZH9;
DE   RecName: Full=Serum paraoxonase/lactonase 3;
DE            EC=3.1.1.2;
DE            EC=3.1.1.81;
DE            EC=3.1.8.1;
GN   Name=PON3;
DR   GO; GO:0018733; F:3,4-dihydrocoumarin hydrolase activity; IEA:Ensembl.
DR   GO; GO:0004063; F:aryldialkylphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004064; F:arylesterase activity; NAS:UniProtKB.
DR   GO; GO:0047856; F:dihydrocoumarin hydrolase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046395; P:carboxylic acid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0046226; P:coumarin catabolic process; IEA:Ensembl.
DR   GO; GO:0010124; P:phenylacetate catabolic process; IEA:Ensembl.
DR   GO; GO:0009605; P:response to external stimulus; NAS:UniProtKB.
//
ID   PONL1_HUMAN             Reviewed;         512 AA.
AC   Q6PEZ8; B7Z564; Q9H5G9;
DE   RecName: Full=Podocan-like protein 1;
DE   Flags: Precursor;
GN   Name=PODNL1; Synonyms=SLRR5B;
//
ID   POP1_HUMAN              Reviewed;        1024 AA.
AC   Q99575; A8K5W9; Q15037;
DE   RecName: Full=Ribonucleases P/MRP protein subunit POP1;
DE            Short=hPOP1;
DE            EC=3.1.26.5;
GN   Name=POP1; Synonyms=KIAA0061;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000171; F:ribonuclease MRP activity; IDA:UniProtKB.
DR   GO; GO:0004526; F:ribonuclease P activity; IDA:UniProtKB.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:InterPro.
DR   GO; GO:0016078; P:tRNA catabolic process; IDA:UniProtKB.
//
ID   POP5_HUMAN              Reviewed;         163 AA.
AC   Q969H6; A6NL80; Q53FS5; Q9Y2Q6;
DE   RecName: Full=Ribonuclease P/MRP protein subunit POP5;
DE            Short=hPop5;
DE            EC=3.1.26.5;
GN   Name=POP5; ORFNames=AD-008, HSPC004, x0003;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   POP7_HUMAN              Reviewed;         140 AA.
AC   O75817; A4D2E0; Q9BV74;
DE   RecName: Full=Ribonuclease P protein subunit p20;
DE            Short=RNaseP protein p20;
DE            EC=3.1.26.5;
DE   AltName: Full=Ribonucleases P/MRP protein subunit POP7 homolog;
DE            Short=hPOP7;
GN   Name=POP7; Synonyms=RPP20;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004526; F:ribonuclease P activity; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   POPD1_HUMAN             Reviewed;         360 AA.
AC   Q8NE79; A8K1R4; E1P5D8; Q5T550; Q5T551; Q8IWC6; Q9HBV0; Q9UNG6;
DE   RecName: Full=Blood vessel epicardial substance;
DE            Short=hBVES;
DE   AltName: Full=Popeye domain-containing protein 1;
DE            Short=Popeye protein 1;
GN   Name=BVES; Synonyms=POP1, POPDC1;
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; NAS:UniProtKB.
DR   GO; GO:0040017; P:positive regulation of locomotion; ISS:UniProtKB.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; ISS:UniProtKB.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   POPD2_HUMAN             Reviewed;         364 AA.
AC   Q9HBU9; Q86UE7;
DE   RecName: Full=Popeye domain-containing protein 2;
DE            Short=Popeye protein 2;
GN   Name=POPDC2; Synonyms=POP2;
//
ID   POPD3_HUMAN             Reviewed;         291 AA.
AC   Q9HBV1; B2RA98; Q5T3Y8; Q8TBW6;
DE   RecName: Full=Popeye domain-containing protein 3;
DE            Short=Popeye protein 3;
GN   Name=POPDC3; Synonyms=POP3;
//
ID   PORCN_HUMAN             Reviewed;         461 AA.
AC   Q9H237; B2RBN8; Q14829; Q9H234; Q9H235; Q9H236; Q9UJU7;
DE   RecName: Full=Protein-cysteine N-palmitoyltransferase porcupine;
DE            EC=2.3.1.-;
DE   AltName: Full=Protein MG61;
GN   Name=PORCN; Synonyms=MG61, PORC, PPN;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   PORED_HUMAN             Reviewed;         318 AA.
AC   Q9H8P0; Q4W5Q6;
DE   RecName: Full=Polyprenol reductase;
DE            EC=1.3.1.94;
DE   AltName: Full=3-oxo-5-alpha-steroid 4-dehydrogenase 3;
DE            EC=1.3.1.22;
DE   AltName: Full=Steroid 5-alpha-reductase 2-like;
DE   AltName: Full=Steroid 5-alpha-reductase 3;
DE            Short=S5AR 3;
DE            Short=SR type 3;
GN   Name=SRD5A3; Synonyms=SRD5A2L;
DR   GO; GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0047751; F:cholestenone 5-alpha-reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IDA:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019348; P:dolichol metabolic process; IDA:UniProtKB.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006489; P:dolichyl diphosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0016095; P:polyprenol catabolic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   PORIM_HUMAN             Reviewed;         208 AA.
AC   Q8N131; Q8IWS2; Q96QV2;
DE   RecName: Full=Porimin;
DE   AltName: Full=Keratinocytes-associated transmembrane protein 3;
DE            Short=KCT-3;
DE   AltName: Full=Pro-oncosis receptor inducing membrane injury;
DE   AltName: Full=Transmembrane protein 123;
DE   Flags: Precursor;
GN   Name=TMEM123; Synonyms=KCT3; ORFNames=PSEC0111, UNQ641/PRO1271;
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0070267; P:oncosis; IDA:UniProtKB.
//
ID   POSTN_HUMAN             Reviewed;         836 AA.
AC   Q15063; Q15064; Q29XZ0; Q3KPJ5; Q5VSY5; Q8IZF9;
DE   RecName: Full=Periostin;
DE            Short=PN;
DE   AltName: Full=Osteoblast-specific factor 2;
DE            Short=OSF-2;
DE   Flags: Precursor;
GN   Name=POSTN; Synonyms=OSF2;
DR   GO; GO:0008201; F:heparin binding; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0008593; P:regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0009888; P:tissue development; IEA:Ensembl.
//
ID   POTB2_HUMAN             Reviewed;         544 AA.
AC   H3BUK9;
DE   RecName: Full=POTE ankyrin domain family member B2;
GN   Name=POTEB2;
//
ID   POTE1_HUMAN             Reviewed;         634 AA.
AC   Q9NUX5; O95018; Q5MJ36; Q9H662; Q9NW19; Q9UG95;
DE   RecName: Full=Protection of telomeres protein 1;
DE            Short=hPot1;
DE   AltName: Full=POT1-like telomere end-binding protein;
GN   Name=POT1;
DR   GO; GO:0017151; F:DEAD/H-box RNA helicase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043047; F:single-stranded telomeric DNA binding; IMP:UniProtKB.
DR   GO; GO:0010521; F:telomerase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:BHF-UCL.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IDA:BHF-UCL.
DR   GO; GO:0032211; P:negative regulation of telomere maintenance via telomerase; IMP:BHF-UCL.
DR   GO; GO:0060383; P:positive regulation of DNA strand elongation; IDA:BHF-UCL.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.
DR   GO; GO:0051973; P:positive regulation of telomerase activity; IDA:BHF-UCL.
DR   GO; GO:0032212; P:positive regulation of telomere maintenance via telomerase; IMP:BHF-UCL.
DR   GO; GO:0016233; P:telomere capping; IMP:BHF-UCL.
DR   GO; GO:0032203; P:telomere formation via telomerase; IDA:BHF-UCL.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; IDA:UniProtKB.
//
ID   POTEB_HUMAN             Reviewed;         581 AA.
AC   Q6S5H4; Q6NXN7; Q6S5H7;
DE   RecName: Full=POTE ankyrin domain family member B;
DE   AltName: Full=ANKRD26-like family B member 1;
DE   AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 15;
DE            Short=POTE-15;
GN   Name=POTEB; Synonyms=A26B1, POTE15;
//
ID   POTEC_HUMAN             Reviewed;         542 AA.
AC   B2RU33;
DE   RecName: Full=POTE ankyrin domain family member C;
DE   AltName: Full=ANKRD26-like family B member 2;
DE   AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 18;
DE            Short=POTE-18;
GN   Name=POTEC; Synonyms=A26B2, POTE18;
//
ID   POTEA_HUMAN             Reviewed;         498 AA.
AC   Q6S8J7; A6ND17; A6ND71; Q6S8J6;
DE   RecName: Full=POTE ankyrin domain family member A;
DE   AltName: Full=ANKRD26-like family A member 1;
DE   AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 8;
DE            Short=POTE-8;
GN   Name=POTEA; Synonyms=A26A1, POTE8;
//
ID   POTEF_HUMAN             Reviewed;        1075 AA.
AC   A5A3E0; A6NC34;
DE   RecName: Full=POTE ankyrin domain family member F;
DE   AltName: Full=ANKRD26-like family C member 1B;
DE   AltName: Full=Chimeric POTE-actin protein;
GN   Name=POTEF; Synonyms=A26C1B;
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   POTED_HUMAN             Reviewed;         584 AA.
AC   Q86YR6; C9JCF7;
DE   RecName: Full=POTE ankyrin domain family member D;
DE   AltName: Full=ANKRD26-like family B member 3;
DE   AltName: Full=Ankyrin repeat domain-containing protein 21;
DE   AltName: Full=Prostate, ovary, testis-expressed protein;
DE            Short=Protein POTE;
GN   Name=POTED; Synonyms=A26B3, ANKRD21, POTE;
//
ID   POTEE_HUMAN             Reviewed;        1075 AA.
AC   Q6S8J3; Q6S8J4; Q6S8J5; Q6S8J8;
DE   RecName: Full=POTE ankyrin domain family member E;
DE   AltName: Full=ANKRD26-like family C member 1A;
DE   AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 2;
DE            Short=POTE-2;
GN   Name=POTEE; Synonyms=A26C1A, POTE2;
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   POTEG_HUMAN             Reviewed;         508 AA.
AC   Q6S5H5; A1L153; A6NMI9; Q6S5H6; Q6S8J2;
DE   RecName: Full=POTE ankyrin domain family member G;
DE   AltName: Full=ANKRD26-like family C member 2;
DE   AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 14;
DE            Short=POTE-14;
GN   Name=POTEG; Synonyms=A26C2, POTE14;
//
ID   POTEM_HUMAN             Reviewed;         508 AA.
AC   A6NI47;
DE   RecName: Full=Putative POTE ankyrin domain family member M;
GN   Name=POTEM;
//
ID   POTEJ_HUMAN             Reviewed;        1038 AA.
AC   P0CG39;
DE   RecName: Full=POTE ankyrin domain family member J;
GN   Name=POTEJ;
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   POTEI_HUMAN             Reviewed;        1075 AA.
AC   P0CG38;
DE   RecName: Full=POTE ankyrin domain family member I;
GN   Name=POTEI;
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   POTEH_HUMAN             Reviewed;         545 AA.
AC   Q6S545; A2CEK4; A6NCI1; A9Z1W0;
DE   RecName: Full=POTE ankyrin domain family member H;
DE   AltName: Full=ANKRD26-like family C member 3;
DE   AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 22;
DE            Short=POTE-22;
GN   Name=POTEH; Synonyms=A26C3, ACTBL1, POTE22;
//
ID   POZP3_HUMAN             Reviewed;         187 AA.
AC   Q6PJE2; F6STJ3; Q12903; Q9BWB4;
DE   RecName: Full=POM121 and ZP3 fusion protein;
DE            Short=POM-ZP3;
GN   Name=POMZP3;
//
ID   PP12C_HUMAN             Reviewed;         782 AA.
AC   Q9BZL4; Q59FK8; Q6ZPD1; Q7L8F7; Q96HW1; Q9H5H5; Q9NT00;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 12C;
DE   AltName: Full=Protein phosphatase 1 myosin-binding subunit of 85 kDa;
DE            Short=Protein phosphatase 1 myosin-binding subunit p85;
GN   Name=PPP1R12C; Synonyms=LENG3, MBS85;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PP13G_HUMAN             Reviewed;         358 AA.
AC   B7ZBB8;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3G;
GN   Name=PPP1R3G;
DR   GO; GO:2001069; F:glycogen binding; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:2000467; P:positive regulation of glycogen (starch) synthase activity; IEA:Ensembl.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IEA:Ensembl.
//
ID   PP13_HUMAN              Reviewed;         139 AA.
AC   Q9UHV8; C5HZ15;
DE   RecName: Full=Galactoside-binding soluble lectin 13;
DE   AltName: Full=Galectin-13;
DE            Short=Gal-13;
DE   AltName: Full=Placental tissue protein 13;
DE            Short=PP13;
DE            Short=Placental protein 13;
GN   Name=LGALS13; Synonyms=PLAC8;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004622; F:lysophospholipase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:ProtInc.
//
ID   PP14A_HUMAN             Reviewed;         147 AA.
AC   Q96A00; Q7Z4X7; Q96S54;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 14A;
DE   AltName: Full=17 kDa PKC-potentiated inhibitory protein of PP1;
DE   AltName: Full=Protein kinase C-potentiated inhibitor protein of 17 kDa;
DE            Short=CPI-17;
GN   Name=PPP1R14A; Synonyms=CPI17, PPP1INL;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
//
ID   PP14B_HUMAN             Reviewed;         147 AA.
AC   Q96C90; Q504S7; Q7KZD7;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 14B;
DE   AltName: Full=Phospholipase C-beta-3 neighbouring gene protein;
GN   Name=PPP1R14B; Synonyms=PLCB3N, PNG;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
//
ID   PP14C_HUMAN             Reviewed;         165 AA.
AC   Q8TAE6; Q5VY83; Q96BB1; Q9H277;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 14C;
DE   AltName: Full=Kinase-enhanced PP1 inhibitor;
DE   AltName: Full=PKC-potentiated PP1 inhibitory protein;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-81;
GN   Name=PPP1R14C; Synonyms=KEPI;
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
//
ID   PP14D_HUMAN             Reviewed;         145 AA.
AC   Q9NXH3; Q4V773;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 14D;
DE   AltName: Full=Gastrointestinal and brain-specific PP1-inhibitory protein 1;
DE            Short=GBPI-1;
GN   Name=PPP1R14D; Synonyms=GBPI;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042325; P:regulation of phosphorylation; IEA:InterPro.
//
ID   PP16A_HUMAN             Reviewed;         528 AA.
AC   Q96I34; D3DWM5;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 16A;
DE   AltName: Full=Myosin phosphatase-targeting subunit 3;
DE   Flags: Precursor;
GN   Name=PPP1R16A; Synonyms=MYPT3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PP16B_HUMAN             Reviewed;         567 AA.
AC   Q96T49; A2RRR6; E9PFS8; O94912; Q5W9G4; Q9NQG4;
DE   RecName: Full=Protein phosphatase 1 regulatory inhibitor subunit 16B;
DE   AltName: Full=Ankyrin repeat domain-containing protein 4;
DE   AltName: Full=CAAX box protein TIMAP;
DE   AltName: Full=TGF-beta-inhibited membrane-associated protein;
DE            Short=hTIMAP;
DE   Flags: Precursor;
GN   Name=PPP1R16B; Synonyms=ANKRD4, KIAA0823;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; NAS:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   PP1A_HUMAN              Reviewed;         330 AA.
AC   P62136; A6NNR3; B2R908; P08129; P20653; P22802; Q07161;
DE   RecName: Full=Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;
DE            Short=PP-1A;
DE            EC=3.1.3.16;
GN   Name=PPP1CA; Synonyms=PPP1A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:Ensembl.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0005981; P:regulation of glycogen catabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   PP1B_HUMAN              Reviewed;         327 AA.
AC   P62140; B2R5V4; D6W565; P37140; Q5U087; Q6FG45;
DE   RecName: Full=Serine/threonine-protein phosphatase PP1-beta catalytic subunit;
DE            Short=PP-1B;
DE            Short=PPP1CD;
DE            EC=3.1.3.16;
DE            EC=3.1.3.53;
GN   Name=PPP1CB;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0017018; F:myosin phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0050115; F:myosin-light-chain-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   PP1G_HUMAN              Reviewed;         323 AA.
AC   P36873;
DE   RecName: Full=Serine/threonine-protein phosphatase PP1-gamma catalytic subunit;
DE            Short=PP-1G;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 1C catalytic subunit;
GN   Name=PPP1CC;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; TAS:Reactome.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019433; P:triglyceride catabolic process; TAS:Reactome.
//
ID   PP1R7_HUMAN             Reviewed;         360 AA.
AC   Q15435; B4DFD4; Q9UQE5; Q9UQE6; Q9Y6K4;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 7;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 22;
GN   Name=PPP1R7; Synonyms=SDS22;
DR   GO; GO:0030234; F:enzyme regulator activity; NAS:UniProtKB.
DR   GO; GO:0008599; F:protein phosphatase type 1 regulator activity; TAS:ProtInc.
DR   GO; GO:0050790; P:regulation of catalytic activity; NAS:GOC.
//
ID   PP1R8_HUMAN             Reviewed;         351 AA.
AC   Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0;
DE   RecName: Full=Nuclear inhibitor of protein phosphatase 1;
DE            Short=NIPP-1;
DE   AltName: Full=Protein phosphatase 1 regulatory inhibitor subunit 8;
DE   Includes:
DE     RecName: Full=Activator of RNA decay;
DE              EC=3.1.4.-;
DE     AltName: Full=ARD-1;
GN   Name=PPP1R8; Synonyms=ARD1, NIPP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008599; F:protein phosphatase type 1 regulator activity; IEA:Ensembl.
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0008995; F:ribonuclease E activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PP1RA_HUMAN             Reviewed;         940 AA.
AC   Q96QC0; O00405;
DE   RecName: Full=Serine/threonine-protein phosphatase 1 regulatory subunit 10;
DE   AltName: Full=MHC class I region proline-rich protein CAT53;
DE   AltName: Full=PP1-binding protein of 114 kDa;
DE   AltName: Full=Phosphatase 1 nuclear targeting subunit;
DE   AltName: Full=Protein FB19;
DE   AltName: Full=p99;
GN   Name=PPP1R10; Synonyms=CAT53, FB19, PNUTS;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006606; P:protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   PP1RB_HUMAN             Reviewed;         126 AA.
AC   O60927;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 11;
DE   AltName: Full=Hemochromatosis candidate gene V protein;
DE            Short=HCG V;
DE   AltName: Full=Protein phosphatase inhibitor 3;
GN   Name=PPP1R11; Synonyms=HCGV, TCTE5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
//
ID   PP2AA_HUMAN             Reviewed;         309 AA.
AC   P67775; P05323; P13197;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;
DE            Short=PP2A-alpha;
DE            EC=3.1.3.16;
DE   AltName: Full=Replication protein C;
DE            Short=RP-C;
GN   Name=PPP2CA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006672; P:ceramide metabolic process; NAS:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; NAS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; NAS:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0070208; P:protein heterotrimerization; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; NAS:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; NAS:UniProtKB.
DR   GO; GO:0031952; P:regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0010469; P:regulation of receptor activity; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; NAS:UniProtKB.
DR   GO; GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB.
//
ID   PP2AB_HUMAN             Reviewed;         309 AA.
AC   P62714; D3DSV4; P11082; Q6FHK5;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform;
DE            Short=PP2A-beta;
DE            EC=3.1.3.16;
GN   Name=PPP2CB;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
//
ID   PP2BA_HUMAN             Reviewed;         521 AA.
AC   Q08209; A1A441; A8K3B7; A8W6Z7; A8W6Z8; B5BUA2; Q8TAW9;
DE   RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform;
DE            EC=3.1.3.16;
DE   AltName: Full=CAM-PRP catalytic subunit;
DE   AltName: Full=Calmodulin-dependent calcineurin A subunit alpha isoform;
GN   Name=PPP3CA; Synonyms=CALNA, CNA;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IDA:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0033173; P:calcineurin-NFAT signaling cascade; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0016311; P:dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0033555; P:multicellular organismal response to stress; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0050804; P:regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0014883; P:transition between fast and slow fiber; IEA:Ensembl.
//
ID   PP2BB_HUMAN             Reviewed;         524 AA.
AC   P16298; P16299; Q5F2F9; Q8N1F0; Q8N3W4;
DE   RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform;
DE            EC=3.1.3.16;
DE   AltName: Full=CAM-PRP catalytic subunit;
DE   AltName: Full=Calmodulin-dependent calcineurin A subunit beta isoform;
GN   Name=PPP3CB; Synonyms=CALNA2, CALNB, CNA2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0033192; F:calmodulin-dependent protein phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046983; F:protein dimerization activity; IPI:UniProtKB.
DR   GO; GO:0030346; F:protein phosphatase 2B binding; IDA:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0048675; P:axon extension; TAS:UniProtKB.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; ISS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; TAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007612; P:learning; TAS:UniProtKB.
DR   GO; GO:0007613; P:memory; TAS:UniProtKB.
DR   GO; GO:0001915; P:negative regulation of T cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; TAS:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0035176; P:social behavior; IEP:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0042098; P:T cell proliferation; NAS:UniProtKB.
//
ID   PP2BC_HUMAN             Reviewed;         512 AA.
AC   P48454; B4DRT5; Q9BSS6; Q9H4M5;
DE   RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform;
DE            EC=3.1.3.16;
DE   AltName: Full=CAM-PRP catalytic subunit;
DE   AltName: Full=Calcineurin, testis-specific catalytic subunit;
DE   AltName: Full=Calmodulin-dependent calcineurin A subunit gamma isoform;
GN   Name=PPP3CC; Synonyms=CALNA3, CNA3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
//
ID   PP2D1_HUMAN             Reviewed;         630 AA.
AC   A8MPX8; Q96LI7;
DE   RecName: Full=Protein phosphatase 2C-like domain-containing protein 1;
GN   Name=PP2D1; Synonyms=C3orf48;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   PP4C_HUMAN              Reviewed;         307 AA.
AC   P60510; P33172;
DE   RecName: Full=Serine/threonine-protein phosphatase 4 catalytic subunit;
DE            Short=PP4C;
DE            Short=Pp4;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase X;
DE            Short=PP-X;
GN   Name=PPP4C; Synonyms=PPP4, PPX;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004704; F:NF-kappaB-inducing kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0038061; P:NIK/NF-kappaB signaling; NAS:GOC.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:UniProtKB.
//
ID   PP4R1_HUMAN             Reviewed;         950 AA.
AC   Q8TF05; Q99774; Q9UNQ7;
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1;
GN   Name=PPP4R1; Synonyms=MEG1, PP4R1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030362; F:protein phosphatase type 4 regulator activity; NAS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; ISS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   PP4R2_HUMAN             Reviewed;         417 AA.
AC   Q9NY27; A8K1I6; Q2TAJ9; Q498B8; Q8WXX6;
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;
GN   Name=PPP4R2; ORFNames=SBBI57;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IMP:UniProtKB.
DR   GO; GO:0030362; F:protein phosphatase type 4 regulator activity; IMP:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0050790; P:regulation of catalytic activity; IMP:GOC.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PP4R4_HUMAN             Reviewed;         873 AA.
AC   Q6NUP7; Q9BUF8; Q9HCF0;
DE   RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 4;
GN   Name=PPP4R4; Synonyms=KIAA1622, PP4R4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019888; F:protein phosphatase regulator activity; IDA:MGI.
DR   GO; GO:0032515; P:negative regulation of phosphoprotein phosphatase activity; IDA:MGI.
DR   GO; GO:0080163; P:regulation of protein serine/threonine phosphatase activity; IDA:MGI.
//
ID   PP4RL_HUMAN             Reviewed;         415 AA.
AC   Q9P1A2; B4DRM4; Q9BZ17; Q9BZ18;
DE   RecName: Full=Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like;
GN   Name=PPP4R1L; Synonyms=C20orf192; ORFNames=PRO1085;
//
ID   PP5D1_HUMAN             Reviewed;         171 AA.
AC   E7EU14; B3KSW5;
DE   RecName: Full=Protein PPP5D1;
DE   AltName: Full=PPP5 TPR repeat domain-containing protein 1;
GN   Name=PPP5D1;
//
ID   PP6R1_HUMAN             Reviewed;         881 AA.
AC   Q9UPN7; Q2M2H3; Q504V2; Q6NVJ6; Q9BU97;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory subunit 1;
DE   AltName: Full=SAPS domain family member 1;
GN   Name=PPP6R1; Synonyms=KIAA1115, PP6R1, SAPS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:MGI.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IDA:MGI.
//
ID   PP6R2_HUMAN             Reviewed;         966 AA.
AC   O75170; A6PVG3; B7Z7T3; Q5U5P3; Q7Z2L2; Q7Z5G5; Q7Z731; Q9UGB9;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory subunit 2;
DE   AltName: Full=SAPS domain family member 2;
GN   Name=PPP6R2; Synonyms=KIAA0685, PP6R2, SAPS2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PP6R3_HUMAN             Reviewed;         873 AA.
AC   Q5H9R7; Q3B7I1; Q3I4Y0; Q3KR35; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2;
AC   Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 regulatory subunit 3;
DE   AltName: Full=SAPS domain family member 3;
DE   AltName: Full=Sporulation-induced transcript 4-associated protein SAPL;
GN   Name=PPP6R3; Synonyms=C11orf23, KIAA1558, PP6R3, SAPL, SAPS3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:MGI.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IDA:MGI.
//
ID   PPA5_HUMAN              Reviewed;         325 AA.
AC   P13686; A8K3V2; Q2TAB1; Q6IAS6; Q9UCJ5; Q9UCJ6; Q9UCJ7;
DE   RecName: Full=Tartrate-resistant acid phosphatase type 5;
DE            Short=TR-AP;
DE            EC=3.1.3.2;
DE   AltName: Full=Tartrate-resistant acid ATPase;
DE            Short=TrATPase;
DE   AltName: Full=Type 5 acid phosphatase;
DE   Flags: Precursor;
GN   Name=ACP5;
DR   GO; GO:0003993; F:acid phosphatase activity; TAS:Reactome.
DR   GO; GO:0008199; F:ferric iron binding; IDA:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032929; P:negative regulation of superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006771; P:riboflavin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PPA6_HUMAN              Reviewed;         428 AA.
AC   Q9NPH0; Q59G61; Q5T490; Q6IAQ3; Q7LG81; Q9UIG6;
DE   RecName: Full=Lysophosphatidic acid phosphatase type 6;
DE            EC=3.1.3.2;
DE   AltName: Full=Acid phosphatase 6, lysophosphatidic;
DE   AltName: Full=Acid phosphatase-like protein 1;
DE   AltName: Full=PACPL1;
DE   Flags: Precursor;
GN   Name=ACP6; Synonyms=ACPL1, LPAP; ORFNames=UNQ205/PRO231;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052642; F:lysophosphatidic acid phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:2001311; P:lysobisphosphatidic acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; IMP:UniProtKB.
//
ID   PPAC2_HUMAN             Reviewed;         295 AA.
AC   Q8IY26; B3KY05; Q5JVJ6; Q8NCK9;
DE   RecName: Full=Presqualene diphosphate phosphatase;
DE            EC=3.1.3.-;
DE   AltName: Full=Phosphatidic acid phosphatase type 2 domain-containing protein 2;
DE            Short=PPAP2 domain-containing protein 2;
GN   Name=PPAPDC2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   PPAC3_HUMAN             Reviewed;         271 AA.
AC   Q8NBV4; Q5T6P0; Q96SS7; Q9BRC3;
DE   RecName: Full=Probable lipid phosphate phosphatase PPAPDC3;
DE            EC=3.1.3.-;
DE   AltName: Full=Phosphatidic acid phosphatase type 2 domain-containing protein 3;
GN   Name=PPAPDC3; Synonyms=C9orf67;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0010832; P:negative regulation of myotube differentiation; IEA:Ensembl.
//
ID   PPAC_HUMAN              Reviewed;         158 AA.
AC   P24666; A8K1L9; B5MCC7; P24667; Q16035; Q16036; Q16725; Q3KQX8;
AC   Q53RU0;
DE   RecName: Full=Low molecular weight phosphotyrosine protein phosphatase;
DE            Short=LMW-PTP;
DE            Short=LMW-PTPase;
DE            EC=3.1.3.48;
DE   AltName: Full=Adipocyte acid phosphatase;
DE   AltName: Full=Low molecular weight cytosolic acid phosphatase;
DE            EC=3.1.3.2;
DE   AltName: Full=Red cell acid phosphatase 1;
GN   Name=ACP1;
DR   GO; GO:0003993; F:acid phosphatase activity; TAS:ProtInc.
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   PPAL_HUMAN              Reviewed;         423 AA.
AC   P11117; E9PCI1; Q561W5; Q9BTU7;
DE   RecName: Full=Lysosomal acid phosphatase;
DE            Short=LAP;
DE            EC=3.1.3.2;
DE   Flags: Precursor;
GN   Name=ACP2;
DR   GO; GO:0003993; F:acid phosphatase activity; TAS:ProtInc.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0007040; P:lysosome organization; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   PPAP_HUMAN              Reviewed;         386 AA.
AC   P15309; D3DNC6; Q5FBY0; Q96KY0; Q96QK9; Q96QM0;
DE   RecName: Full=Prostatic acid phosphatase;
DE            Short=PAP;
DE            EC=3.1.3.2;
DE   AltName: Full=5'-nucleotidase;
DE            Short=5'-NT;
DE            EC=3.1.3.5;
DE   AltName: Full=Ecto-5'-nucleotidase;
DE   AltName: Full=Thiamine monophosphatase;
DE            Short=TMPase;
DE   Contains:
DE     RecName: Full=PAPf39;
DE   Flags: Precursor;
GN   Name=ACPP;
DR   GO; GO:0008253; F:5'-nucleotidase activity; IDA:UniProt.
DR   GO; GO:0003993; F:acid phosphatase activity; IMP:UniProt.
DR   GO; GO:0033265; F:choline binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0052642; F:lysophosphatidic acid phosphatase activity; IDA:UniProt.
DR   GO; GO:0016791; F:phosphatase activity; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042131; F:thiamine phosphate phosphatase activity; ISS:UniProt.
DR   GO; GO:0046085; P:adenosine metabolic process; IDA:UniProt.
DR   GO; GO:0016311; P:dephosphorylation; IMP:UniProt.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:Ensembl.
DR   GO; GO:0060168; P:positive regulation of adenosine receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:Ensembl.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IMP:UniProt.
DR   GO; GO:0006772; P:thiamine metabolic process; ISS:UniProt.
//
ID   PPARA_HUMAN             Reviewed;         468 AA.
AC   Q07869; B0G0X3; Q16241; Q6I9S0; Q92486; Q92689; Q9Y3N1;
DE   RecName: Full=Peroxisome proliferator-activated receptor alpha;
DE            Short=PPAR-alpha;
DE   AltName: Full=Nuclear receptor subfamily 1 group C member 1;
GN   Name=PPARA; Synonyms=NR1C1, PPAR;
DR   GuidetoPHARMACOLOGY; 593; -.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IDA:BHF-UCL.
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035095; P:behavioral response to nicotine; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0070166; P:enamel mineralization; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; TAS:ProtInc.
DR   GO; GO:0015908; P:fatty acid transport; TAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042157; P:lipoprotein metabolic process; IEA:Ensembl.
DR   GO; GO:0032099; P:negative regulation of appetite; ISS:UniProtKB.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0010887; P:negative regulation of cholesterol storage; IDA:BHF-UCL.
DR   GO; GO:0045820; P:negative regulation of glycolytic process; IC:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0010871; P:negative regulation of receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010891; P:negative regulation of sequestering of triglyceride; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; TAS:UniProtKB.
DR   GO; GO:0046321; P:positive regulation of fatty acid oxidation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0072366; P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0072363; P:regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0072369; P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   PPARD_HUMAN             Reviewed;         441 AA.
AC   Q03181; A8K6J6; B4E3V3; B6ZGS1; B7Z3W1; E9PE18; Q5D1P0; Q7Z5K0;
AC   Q9BUD4;
DE   RecName: Full=Peroxisome proliferator-activated receptor delta;
DE            Short=PPAR-delta;
DE   AltName: Full=NUCI;
DE   AltName: Full=Nuclear hormone receptor 1;
DE            Short=NUC1;
DE   AltName: Full=Nuclear receptor subfamily 1 group C member 2;
DE   AltName: Full=Peroxisome proliferator-activated receptor beta;
DE            Short=PPAR-beta;
GN   Name=PPARD; Synonyms=NR1C2, PPARB;
DR   GuidetoPHARMACOLOGY; 594; -.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0070539; F:linoleic acid binding; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008366; P:axon ensheathment; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0031589; P:cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:UniProtKB.
DR   GO; GO:0046697; P:decidualization; TAS:UniProtKB.
DR   GO; GO:0007566; P:embryo implantation; TAS:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; ISS:UniProtKB.
DR   GO; GO:0009062; P:fatty acid catabolic process; TAS:UniProtKB.
DR   GO; GO:0015908; P:fatty acid transport; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0006006; P:glucose metabolic process; NAS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; NAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0051546; P:keratinocyte migration; IEA:Ensembl.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; ISS:UniProtKB.
DR   GO; GO:0009299; P:mRNA transcription; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0032966; P:negative regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045684; P:positive regulation of epidermis development; IEA:Ensembl.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; NAS:UniProtKB.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0006029; P:proteoglycan metabolic process; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006776; P:vitamin A metabolic process; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   PPARG_HUMAN             Reviewed;         505 AA.
AC   P37231; A8K3G6; B5BUA1; O00684; O00710; O14515; Q0QJH8; Q15178;
AC   Q15179; Q15180; Q15832; Q86U60; Q96J12;
DE   RecName: Full=Peroxisome proliferator-activated receptor gamma;
DE            Short=PPAR-gamma;
DE   AltName: Full=Nuclear receptor subfamily 1 group C member 3;
GN   Name=PPARG; Synonyms=NR1C3;
DR   GuidetoPHARMACOLOGY; 595; -.
DR   GO; GO:0033613; F:activating transcription factor binding; IDA:BHF-UCL.
DR   GO; GO:0050544; F:arachidonic acid binding; ISS:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0004955; F:prostaglandin receptor activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046965; F:retinoid X receptor binding; IDA:BHF-UCL.
DR   GO; GO:0001012; F:RNA polymerase II regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0048469; P:cell maturation; IDA:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0019395; P:fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GOC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; TAS:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0042953; P:lipoprotein transport; IDA:BHF-UCL.
DR   GO; GO:0015909; P:long-chain fatty acid transport; ISS:BHF-UCL.
DR   GO; GO:0045713; P:low-density lipoprotein particle receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0030224; P:monocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0002674; P:negative regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0010887; P:negative regulation of cholesterol storage; IDA:BHF-UCL.
DR   GO; GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0010871; P:negative regulation of receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0010891; P:negative regulation of sequestering of triglyceride; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0035357; P:peroxisome proliferator activated receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0001890; P:placenta development; ISS:BHF-UCL.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:HGNC.
DR   GO; GO:0046321; P:positive regulation of fatty acid oxidation; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0008217; P:regulation of blood pressure; IMP:BHF-UCL.
DR   GO; GO:0060694; P:regulation of cholesterol transporter activity; IC:BHF-UCL.
DR   GO; GO:0060850; P:regulation of transcription involved in cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0033993; P:response to lipid; ISS:BHF-UCL.
DR   GO; GO:0055098; P:response to low-density lipoprotein particle; IDA:BHF-UCL.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0050872; P:white fat cell differentiation; TAS:UniProtKB.
//
ID   PPAT_HUMAN              Reviewed;         426 AA.
AC   Q9BZG2; C0H3P7; Q9BZG3; Q9BZG4;
DE   RecName: Full=Testicular acid phosphatase;
DE            EC=3.1.3.2;
DE   Flags: Precursor;
GN   Name=ACPT;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
//
ID   PPB1_HUMAN              Reviewed;         535 AA.
AC   P05187; P05188; P06861; Q53S78; Q96DB7;
DE   RecName: Full=Alkaline phosphatase, placental type;
DE            EC=3.1.3.1;
DE   AltName: Full=Alkaline phosphatase Regan isozyme;
DE   AltName: Full=Placental alkaline phosphatase 1;
DE            Short=PLAP-1;
DE   Flags: Precursor;
GN   Name=ALPP; Synonyms=PLAP;
DR   GO; GO:0004035; F:alkaline phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
//
ID   PPBI_HUMAN              Reviewed;         528 AA.
AC   P09923; B2R7Y4; Q53S80; Q9UBV5; Q9UCL2;
DE   RecName: Full=Intestinal-type alkaline phosphatase;
DE            Short=IAP;
DE            Short=Intestinal alkaline phosphatase;
DE            EC=3.1.3.1;
DE   Flags: Precursor;
GN   Name=ALPI;
DR   GO; GO:0004035; F:alkaline phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; ISS:UniProtKB.
//
ID   PPBN_HUMAN              Reviewed;         532 AA.
AC   P10696; A8KAF2; Q16727; Q53S81; Q96CM1;
DE   RecName: Full=Alkaline phosphatase, placental-like;
DE            EC=3.1.3.1;
DE   AltName: Full=ALP-1;
DE   AltName: Full=Alkaline phosphatase Nagao isozyme;
DE   AltName: Full=Germ cell alkaline phosphatase;
DE            Short=GCAP;
DE   AltName: Full=Placental alkaline phosphatase-like;
DE            Short=PLAP-like;
DE   Flags: Precursor;
GN   Name=ALPPL2; Synonyms=ALPPL;
DR   GO; GO:0004035; F:alkaline phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016311; P:dephosphorylation; NAS:GOC.
//
ID   PPBT_HUMAN              Reviewed;         524 AA.
AC   P05186; A1A4E7; B2RMP8; B7Z387; B7Z4Y6; O75090; Q2TAI7; Q59EJ7;
AC   Q5BKZ5; Q5VTG5; Q6NZI8; Q8WU32; Q9UBK0;
DE   RecName: Full=Alkaline phosphatase, tissue-nonspecific isozyme;
DE            Short=AP-TNAP;
DE            Short=TNSALP;
DE            EC=3.1.3.1;
DE   AltName: Full=Alkaline phosphatase liver/bone/kidney isozyme;
DE   Flags: Precursor;
GN   Name=ALPL;
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016462; F:pyrophosphatase activity; IDA:MGI.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0071529; P:cementum mineralization; IEA:Ensembl.
DR   GO; GO:0003006; P:developmental process involved in reproduction; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEP:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   PPC1A_HUMAN             Reviewed;         271 AA.
AC   Q5VZY2; A2RU82; Q08EQ2; Q0IIP2; Q495B4; Q5VZY1;
DE   RecName: Full=Phosphatidate phosphatase PPAPDC1A;
DE            EC=3.1.3.4;
DE   AltName: Full=Phosphatidic acid phosphatase type 2 domain-containing protein 1A;
GN   Name=PPAPDC1A; Synonyms=DPPL2, PPAPDC1;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0046839; P:phospholipid dephosphorylation; IDA:UniProtKB.
//
ID   PPC1B_HUMAN             Reviewed;         264 AA.
AC   Q8NEB5; C9JKF5; Q3KQX6; Q9BY45;
DE   RecName: Full=Phosphatidate phosphatase PPAPDC1B;
DE            EC=3.1.3.4;
DE   AltName: Full=Phosphatidic acid phosphatase type 2 domain-containing protein 1B;
GN   Name=PPAPDC1B; Synonyms=DPPL1, HTPAP;
DR   GO; GO:0008195; F:phosphatidate phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046839; P:phospholipid dephosphorylation; IDA:UniProtKB.
//
ID   PPCEL_HUMAN             Reviewed;         727 AA.
AC   Q4J6C6; A7E2X6; D6W5A3; O43163; Q4J6C3; Q4J6C4; Q4ZG39; Q6ZMW7;
AC   Q96DW7;
DE   RecName: Full=Prolyl endopeptidase-like;
DE            EC=3.4.21.-;
DE   AltName: Full=Prolylendopeptidase-like;
GN   Name=PREPL; Synonyms=KIAA0436;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0070008; F:serine-type exopeptidase activity; IEA:InterPro.
//
ID   PPCE_HUMAN              Reviewed;         710 AA.
AC   P48147; Q8N6D4;
DE   RecName: Full=Prolyl endopeptidase;
DE            Short=PE;
DE            EC=3.4.21.26;
DE   AltName: Full=Post-proline cleaving enzyme;
GN   Name=PREP; Synonyms=PEP;
DR   GuidetoPHARMACOLOGY; 2395; -.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0070008; F:serine-type exopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   PPCS_HUMAN              Reviewed;         311 AA.
AC   Q9HAB8; Q3KQT2; Q5VVM0;
DE   RecName: Full=Phosphopantothenate--cysteine ligase;
DE            EC=6.3.2.5;
DE   AltName: Full=Phosphopantothenoylcysteine synthetase;
DE            Short=PPC synthetase;
GN   Name=PPCS; Synonyms=COAB;
DR   GO; GO:0004632; F:phosphopantothenate--cysteine ligase activity; IDA:UniProtKB.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009108; P:coenzyme biosynthetic process; TAS:Reactome.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PPCT_HUMAN              Reviewed;         214 AA.
AC   Q9UKL6; Q9BSC9; Q9UIT3; Q9UKW7;
DE   RecName: Full=Phosphatidylcholine transfer protein;
DE            Short=PC-TP;
DE   AltName: Full=START domain-containing protein 2;
DE            Short=StARD2;
DE   AltName: Full=StAR-related lipid transfer protein 2;
GN   Name=PCTP; Synonyms=STARD2;
DR   GO; GO:0031210; F:phosphatidylcholine binding; IDA:UniProtKB.
DR   GO; GO:0008525; F:phosphatidylcholine transporter activity; IDA:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0006869; P:lipid transport; NAS:UniProtKB.
DR   GO; GO:0015914; P:phospholipid transport; IDA:UniProtKB.
//
ID   PPDPF_HUMAN             Reviewed;         114 AA.
AC   Q9H3Y8; E1P5J2; Q4VXP1; Q9H3Y7;
DE   RecName: Full=Pancreatic progenitor cell differentiation and proliferation factor;
DE   AltName: Full=Exocrine differentiation and proliferation factor;
GN   Name=PPDPF; Synonyms=C20orf149, EXPDF;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   PPE1_HUMAN              Reviewed;         653 AA.
AC   O14829; A6NHP4; A8K348; O15253; Q9NU21; Q9UJH0;
DE   RecName: Full=Serine/threonine-protein phosphatase with EF-hands 1;
DE            Short=PPEF-1;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase with EF calcium-binding domain;
DE            Short=PPEF;
DE   AltName: Full=Serine/threonine-protein phosphatase 7;
DE            Short=PP7;
GN   Name=PPEF1; Synonyms=PPEF, PPP7C;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
DR   GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
//
ID   PPE2_HUMAN              Reviewed;         753 AA.
AC   O14830; O14831;
DE   RecName: Full=Serine/threonine-protein phosphatase with EF-hands 2;
DE            Short=PPEF-2;
DE            EC=3.1.3.16;
GN   Name=PPEF2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030544; F:Hsp70 protein binding; IDA:BHF-UCL.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:BHF-UCL.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:InterPro.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0043506; P:regulation of JUN kinase activity; IC:BHF-UCL.
DR   GO; GO:0043405; P:regulation of MAP kinase activity; IC:BHF-UCL.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   PPGB_HUMAN              Reviewed;         480 AA.
AC   P10619; B2R798; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68;
DE   RecName: Full=Lysosomal protective protein;
DE            EC=3.4.16.5;
DE   AltName: Full=Carboxypeptidase C;
DE   AltName: Full=Carboxypeptidase L;
DE   AltName: Full=Cathepsin A;
DE   AltName: Full=Protective protein cathepsin A;
DE            Short=PPCA;
DE   AltName: Full=Protective protein for beta-galactosidase;
DE   Contains:
DE     RecName: Full=Lysosomal protective protein 32 kDa chain;
DE   Contains:
DE     RecName: Full=Lysosomal protective protein 20 kDa chain;
DE   Flags: Precursor;
GN   Name=CTSA; Synonyms=PPGB;
DR   GO; GO:0004180; F:carboxypeptidase activity; TAS:ProtInc.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   PPHLN_HUMAN             Reviewed;         458 AA.
AC   Q8NEY8; E9PAX8; Q86YT2; Q8IXN3; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6;
AC   Q9P0R9;
DE   RecName: Full=Periphilin-1;
DE   AltName: Full=Gastric cancer antigen Ga50;
GN   Name=PPHLN1; ORFNames=HSPC206, HSPC232;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   PPIA_HUMAN              Reviewed;         165 AA.
AC   P62937; A8K220; P05092; Q3KQW3; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9;
AC   Q9UC61;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase A;
DE            Short=PPIase A;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin A;
DE   AltName: Full=Cyclosporin A-binding protein;
DE   AltName: Full=Rotamase A;
DE   Contains:
DE     RecName: Full=Peptidyl-prolyl cis-trans isomerase A, N-terminally processed;
GN   Name=PPIA; Synonyms=CYPA;
DR   GuidetoPHARMACOLOGY; 2751; -.
DR   GO; GO:0042277; F:peptide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
DR   GO; GO:0046790; F:virion binding; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030260; P:entry into host cell; TAS:Reactome.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0034389; P:lipid particle organization; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:UniProtKB.
DR   GO; GO:0045069; P:regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0006278; P:RNA-dependent DNA replication; TAS:Reactome.
DR   GO; GO:0019061; P:uncoating of virus; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019076; P:viral release from host cell; TAS:UniProtKB.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   PPIB_HUMAN              Reviewed;         216 AA.
AC   P23284; A8K534; Q6IBH5; Q9BVK5;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase B;
DE            Short=PPIase B;
DE            EC=5.2.1.8;
DE   AltName: Full=CYP-S1;
DE   AltName: Full=Cyclophilin B;
DE   AltName: Full=Rotamase B;
DE   AltName: Full=S-cyclophilin;
DE            Short=SCYLP;
DE   Flags: Precursor;
GN   Name=PPIB; Synonyms=CYPB;
DR   GO; GO:0042277; F:peptide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; ISS:UniProt.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0060348; P:bone development; IMP:UniProt.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProt.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IMP:UniProt.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; ISS:UniProt.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
//
ID   PPIC_HUMAN              Reviewed;         212 AA.
AC   P45877; A4LBB5;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase C;
DE            Short=PPIase C;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin C;
DE   AltName: Full=Rotamase C;
GN   Name=PPIC; Synonyms=CYPC;
DR   GO; GO:0016018; F:cyclosporin A binding; TAS:ProtInc.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PPID_HUMAN              Reviewed;         370 AA.
AC   Q08752; B2R9V2;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase D;
DE            Short=PPIase D;
DE            EC=5.2.1.8;
DE   AltName: Full=40 kDa peptidyl-prolyl cis-trans isomerase;
DE   AltName: Full=Cyclophilin-40;
DE            Short=CYP-40;
DE   AltName: Full=Cyclophilin-related protein;
DE   AltName: Full=Rotamase D;
GN   Name=PPID; Synonyms=CYP40, CYPD;
DR   GO; GO:0016018; F:cyclosporin A binding; TAS:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; ISS:UniProtKB.
DR   GO; GO:0051879; F:Hsp90 protein binding; IDA:UniProtKB.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071492; P:cellular response to UV-A; IMP:UniProtKB.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB.
DR   GO; GO:0034389; P:lipid particle organization; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; ISS:UniProtKB.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019076; P:viral release from host cell; TAS:UniProtKB.
//
ID   PPIE_HUMAN              Reviewed;         301 AA.
AC   Q9UNP9; B2R971; O43634; O43635; Q32Q72; Q3S611; Q5TGA0; Q5TGA2;
AC   Q5TGA3; Q9UIZ5;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase E;
DE            Short=PPIase E;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin E;
DE   AltName: Full=Cyclophilin-33;
DE   AltName: Full=Rotamase E;
GN   Name=PPIE; Synonyms=CYP33;
DR   GO; GO:0016018; F:cyclosporin A binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; TAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
//
ID   PPIF_HUMAN              Reviewed;         207 AA.
AC   P30405; Q5W131;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase F, mitochondrial;
DE            Short=PPIase F;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin D;
DE            Short=CyP-D;
DE            Short=CypD;
DE   AltName: Full=Cyclophilin F;
DE   AltName: Full=Mitochondrial cyclophilin;
DE            Short=CyP-M;
DE   AltName: Full=Rotamase F;
DE   Flags: Precursor;
GN   Name=PPIF; Synonyms=CYP3;
DR   GO; GO:0016018; F:cyclosporin A binding; IEA:Ensembl.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0071243; P:cellular response to arsenic-containing substance; ISS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; ISS:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0090324; P:negative regulation of oxidative phosphorylation; ISS:UniProtKB.
DR   GO; GO:2000276; P:negative regulation of oxidative phosphorylation uncoupler activity; ISS:UniProtKB.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0010940; P:positive regulation of necrotic cell death; IEA:Ensembl.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0046902; P:regulation of mitochondrial membrane permeability; ISS:UniProtKB.
DR   GO; GO:1902445; P:regulation of mitochondrial membrane permeability involved in programmed necrotic cell death; IMP:UniProtKB.
DR   GO; GO:0010849; P:regulation of proton-transporting ATPase activity, rotational mechanism; ISS:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; ISS:UniProtKB.
//
ID   PPIG_HUMAN              Reviewed;         754 AA.
AC   Q13427; D3DPC5; D3DPC6; O00706; Q53R40; Q53SN4; Q96DG9;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase G;
DE            Short=PPIase G;
DE            Short=Peptidyl-prolyl isomerase G;
DE            EC=5.2.1.8;
DE   AltName: Full=CASP10;
DE   AltName: Full=Clk-associating RS-cyclophilin;
DE            Short=CARS-Cyp;
DE            Short=CARS-cyclophilin;
DE            Short=SR-cyclophilin;
DE            Short=SR-cyp;
DE            Short=SRcyp;
DE   AltName: Full=Cyclophilin G;
DE   AltName: Full=Rotamase G;
GN   Name=PPIG;
DR   GO; GO:0016018; F:cyclosporin A binding; TAS:ProtInc.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   PPIH_HUMAN              Reviewed;         177 AA.
AC   O43447;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase H;
DE            Short=PPIase H;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase H;
DE   AltName: Full=Small nuclear ribonucleoprotein particle-specific cyclophilin H;
DE            Short=CypH;
DE   AltName: Full=U-snRNP-associated cyclophilin SnuCyp-20;
DE            Short=USA-CYP;
GN   Name=PPIH; Synonyms=CYP20, CYPH;
DR   GO; GO:0016018; F:cyclosporin A binding; TAS:ProtInc.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:BHF-UCL.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:BHF-UCL.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IDA:GOC.
//
ID   PPIL1_HUMAN             Reviewed;         166 AA.
AC   Q9Y3C6; O15001; Q5TDC9;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 1;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase PPIL1;
GN   Name=PPIL1; Synonyms=CYPL1; ORFNames=CGI-124, UNQ2425/PRO4984;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PPIL2_HUMAN             Reviewed;         520 AA.
AC   Q13356; Q13357; Q8TAH2; Q9BWR8;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 2;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin-60;
DE   AltName: Full=Cyclophilin-like protein Cyp-60;
DE   AltName: Full=Rotamase PPIL2;
GN   Name=PPIL2;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:MGI.
//
ID   PPIL3_HUMAN             Reviewed;         161 AA.
AC   Q9H2H8; Q86WF9; Q96IA9; Q9BXZ1;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 3;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin J;
DE            Short=CyPJ;
DE   AltName: Full=Cyclophilin-like protein PPIL3;
DE   AltName: Full=Rotamase PPIL3;
GN   Name=PPIL3;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PPIL4_HUMAN             Reviewed;         492 AA.
AC   Q8WUA2; B2RD34; Q7Z3Q5;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 4;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin-like protein PPIL4;
DE   AltName: Full=Rotamase PPIL4;
GN   Name=PPIL4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PPIL6_HUMAN             Reviewed;         311 AA.
AC   Q8IXY8; A9NIU0; A9NIU9;
DE   RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 6;
DE            Short=PPIase;
DE            EC=5.2.1.8;
DE   AltName: Full=Cyclophilin-like protein PPIL6;
DE   AltName: Full=Rotamase PPIL6;
GN   Name=PPIL6;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PPIP1_HUMAN             Reviewed;         416 AA.
AC   O43586; B5BU74; B5BUK4; O43585; O95657;
DE   RecName: Full=Proline-serine-threonine phosphatase-interacting protein 1;
DE            Short=PEST phosphatase-interacting protein 1;
DE   AltName: Full=CD2-binding protein 1;
DE   AltName: Full=H-PIP;
GN   Name=PSTPIP1; Synonyms=CD2BP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PPIP2_HUMAN             Reviewed;         334 AA.
AC   Q9H939;
DE   RecName: Full=Proline-serine-threonine phosphatase-interacting protein 2;
DE            Short=PEST phosphatase-interacting protein 2;
GN   Name=PSTPIP2;
//
ID   PPL13_HUMAN             Reviewed;         139 AA.
AC   Q8TCE9; A8MPV8; B2R530; C5HZ19; Q7Z4X8; Q96KD4; Q96KD5; Q96KD6;
AC   Q9NR03;
DE   RecName: Full=Placental protein 13-like;
DE   AltName: Full=Charcot-Leyden crystal protein 2;
DE            Short=CLC2;
DE   AltName: Full=Galectin-14;
DE            Short=Gal-14;
GN   Name=LGALS14; Synonyms=PPL13;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   PPLA_HUMAN              Reviewed;          52 AA.
AC   P26678;
DE   RecName: Full=Cardiac phospholamban;
DE            Short=PLB;
GN   Name=PLN; Synonyms=PLB;
DR   GO; GO:0051117; F:ATPase binding; ISS:BHF-UCL.
DR   GO; GO:0042030; F:ATPase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:InterPro.
DR   GO; GO:0004857; F:enzyme inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0086023; P:adrenergic receptor signaling pathway involved in heart process; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; NAS:ProtInc.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IC:BHF-UCL.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; IDA:BHF-UCL.
DR   GO; GO:1901877; P:negative regulation of calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0090281; P:negative regulation of calcium ion import; ISS:BHF-UCL.
DR   GO; GO:1902081; P:negative regulation of calcium ion import into sarcoplasmic reticulum; ISS:BHF-UCL.
DR   GO; GO:1901020; P:negative regulation of calcium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0051926; P:negative regulation of calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:1901895; P:negative regulation of calcium-transporting ATPase activity; IDA:BHF-UCL.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:BHF-UCL.
DR   GO; GO:0010459; P:negative regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:1901894; P:regulation of calcium-transporting ATPase activity; IDA:UniProtKB.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IC:BHF-UCL.
DR   GO; GO:0086036; P:regulation of cardiac muscle cell membrane potential; IC:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IMP:BHF-UCL.
DR   GO; GO:1901897; P:regulation of relaxation of cardiac muscle; IC:BHF-UCL.
DR   GO; GO:0060314; P:regulation of ryanodine-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IC:BHF-UCL.
DR   GO; GO:0086092; P:regulation of the force of heart contraction by cardiac conduction; IEA:Ensembl.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; TAS:BHF-UCL.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
//
ID   PPM1A_HUMAN             Reviewed;         382 AA.
AC   P35813; B5BU11; J3KNM0; O75551;
DE   RecName: Full=Protein phosphatase 1A;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 2C isoform alpha;
DE            Short=PP2C-alpha;
DE   AltName: Full=Protein phosphatase IA;
GN   Name=PPM1A; Synonyms=PPPM1A;
DR   GO; GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006499; P:N-terminal protein myristoylation; ISS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.
DR   GO; GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
//
ID   PPM1B_HUMAN             Reviewed;         479 AA.
AC   O75688; Q461Q2; Q4J6C1; Q4J6C2; Q658R4; Q96ER6; Q9HAY8;
DE   RecName: Full=Protein phosphatase 1B;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 2C isoform beta;
DE            Short=PP2C-beta;
GN   Name=PPM1B; Synonyms=PP2CB;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006499; P:N-terminal protein myristoylation; ISS:UniProtKB.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IMP:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032688; P:negative regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.
//
ID   PPM1D_HUMAN             Reviewed;         605 AA.
AC   O15297; Q53XP4; Q6P991;
DE   RecName: Full=Protein phosphatase 1D;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 2C isoform delta;
DE            Short=PP2C-delta;
DE   AltName: Full=Protein phosphatase magnesium-dependent 1 delta;
DE   AltName: Full=p53-induced protein phosphatase 1;
GN   Name=PPM1D; Synonyms=WIP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; TAS:ProtInc.
//
ID   PPM1E_HUMAN             Reviewed;         764 AA.
AC   Q8WY54; Q68DW1; Q7LAF3; Q9UPT0;
DE   RecName: Full=Protein phosphatase 1E;
DE            EC=3.1.3.16;
DE   AltName: Full=Ca(2+)/calmodulin-dependent protein kinase phosphatase N;
DE            Short=CaMKP-N;
DE   AltName: Full=CaMKP-nucleus;
DE            Short=CaMKN;
DE   AltName: Full=Partner of PIX 1;
DE   AltName: Full=Partner of PIX-alpha;
DE            Short=Partner of PIXA;
GN   Name=PPM1E; Synonyms=CAMKN, KIAA1072, POPX1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
//
ID   PPM1F_HUMAN             Reviewed;         454 AA.
AC   P49593; A8K6G3; Q96PM2;
DE   RecName: Full=Protein phosphatase 1F;
DE            EC=3.1.3.16;
DE   AltName: Full=Ca(2+)/calmodulin-dependent protein kinase phosphatase;
DE            Short=CaM-kinase phosphatase;
DE            Short=CaMKPase;
DE   AltName: Full=Partner of PIX 2;
DE   AltName: Full=Protein fem-2 homolog;
DE            Short=hFem-2;
GN   Name=PPM1F; Synonyms=KIAA0015, POPX2;
DR   GO; GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0016576; P:histone dephosphorylation; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0044387; P:negative regulation of protein kinase activity by regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:UniProtKB.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045927; P:positive regulation of growth; IMP:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
//
ID   PPM1G_HUMAN             Reviewed;         546 AA.
AC   O15355;
DE   RecName: Full=Protein phosphatase 1G;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 1C;
DE   AltName: Full=Protein phosphatase 2C isoform gamma;
DE            Short=PP2C-gamma;
DE   AltName: Full=Protein phosphatase magnesium-dependent 1 gamma;
GN   Name=PPM1G; Synonyms=PPM1C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PPM1H_HUMAN             Reviewed;         514 AA.
AC   Q9ULR3; B1Q2A9; B2RXG4; Q6PI86;
DE   RecName: Full=Protein phosphatase 1H;
DE            EC=3.1.3.16;
GN   Name=PPM1H; Synonyms=ARHCL1, KIAA1157, URCC2;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
//
ID   PPM1J_HUMAN             Reviewed;         505 AA.
AC   Q5JR12; B3KSB7; Q6DKJ7; Q96EZ7; Q9UF84;
DE   RecName: Full=Protein phosphatase 1J;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 2C isoform zeta;
DE            Short=PP2C-zeta;
GN   Name=PPM1J; Synonyms=PPP2CZ;
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:Ensembl.
//
ID   PPM1K_HUMAN             Reviewed;         372 AA.
AC   Q8N3J5; B2RAZ1; Q05CT5; Q49AB5; Q4W5E6; Q56AN8; Q8IUZ7; Q8IXG7;
AC   Q8ND70; Q96NT4;
DE   RecName: Full=Protein phosphatase 1K, mitochondrial;
DE            EC=3.1.3.16;
DE   AltName: Full=PP2C domain-containing protein phosphatase 1K;
DE   AltName: Full=PP2C-like mitochondrial protein;
DE   AltName: Full=PP2C-type mitochondrial phosphoprotein phosphatase;
DE            Short=PTMP;
DE   AltName: Full=Protein phosphatase 2C isoform kappa;
DE            Short=PP2C-kappa;
DE   Flags: Precursor;
GN   Name=PPM1K; Synonyms=PP2CM;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:InterPro.
//
ID   PPM1L_HUMAN             Reviewed;         360 AA.
AC   Q5SGD2; Q2M3J2; Q96NM7;
DE   RecName: Full=Protein phosphatase 1L;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 1-like;
DE   AltName: Full=Protein phosphatase 2C isoform epsilon;
DE            Short=PP2C-epsilon;
GN   Name=PPM1L; Synonyms=PP2CE;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IEA:Ensembl.
//
ID   PPM1M_HUMAN             Reviewed;         270 AA.
AC   Q96MI6; Q8N8J9; Q96DB8;
DE   RecName: Full=Protein phosphatase 1M;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase 2C isoform eta;
DE            Short=PP2C-eta;
DE            Short=PP2CE;
GN   Name=PPM1M; Synonyms=PPM1E;
DR   GO; GO:0008420; F:CTD phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; ISS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
//
ID   PPM1N_HUMAN             Reviewed;         430 AA.
AC   Q8N819; Q6P662;
DE   RecName: Full=Probable protein phosphatase 1N;
DE            EC=3.1.3.16;
GN   Name=PPM1N;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
//
ID   PPME1_HUMAN             Reviewed;         386 AA.
AC   Q9Y570; B3KMU6; B5MEE7; J3QT22; Q8WYG8; Q9NVT5; Q9UI18;
DE   RecName: Full=Protein phosphatase methylesterase 1;
DE            Short=PME-1;
DE            EC=3.1.1.89;
GN   Name=PPME1; Synonyms=PME1; ORFNames=PP2593, PRO0750;
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0051722; F:protein C-terminal methylesterase activity; IDA:HGNC.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:HGNC.
DR   GO; GO:0019903; F:protein phosphatase binding; IDA:HGNC.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:HGNC.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006482; P:protein demethylation; IEA:InterPro.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
//
ID   PPN_HUMAN               Reviewed;        1278 AA.
AC   O95428; B4DES8; B4DGE6; Q659F2; Q6UXJ4; Q6ZNM1; Q6ZUJ0; Q7Z681;
AC   Q8IVU0;
DE   RecName: Full=Papilin;
DE   Flags: Precursor;
GN   Name=PAPLN; ORFNames=UNQ2420/PRO4977;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PPOX_HUMAN              Reviewed;         477 AA.
AC   P50336; D3DVG0; Q5VTW8;
DE   RecName: Full=Protoporphyrinogen oxidase;
DE            Short=PPO;
DE            EC=1.3.3.4;
GN   Name=PPOX;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; TAS:UniProtKB.
DR   GO; GO:0004729; F:oxygen-dependent protoporphyrinogen oxidase activity; IDA:UniProtKB.
DR   GO; GO:0006783; P:heme biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006782; P:protoporphyrinogen IX biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PPP5_HUMAN              Reviewed;         499 AA.
AC   P53041; Q16722; Q53XV2;
DE   RecName: Full=Serine/threonine-protein phosphatase 5;
DE            Short=PP5;
DE            EC=3.1.3.16;
DE   AltName: Full=Protein phosphatase T;
DE            Short=PP-T;
DE            Short=PPT;
GN   Name=PPP5C; Synonyms=PPP5;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   PPP6_HUMAN              Reviewed;         305 AA.
AC   O00743; B2R5V6; B7Z2W9; B7Z5K9; Q5U0A2; Q9UIC9;
DE   RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit;
DE            Short=PP6C;
DE            EC=3.1.3.16;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed;
GN   Name=PPP6C; Synonyms=PPP6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:MGI.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:MGI.
//
ID   PPR17_HUMAN             Reviewed;         155 AA.
AC   O96001; B4DE58; Q9UDQ0;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 17;
DE   AltName: Full=G-substrate;
GN   Name=PPP1R17; Synonyms=C7orf16, GSBS;
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0010921; P:regulation of phosphatase activity; ISS:UniProtKB.
//
ID   PPR18_HUMAN             Reviewed;         613 AA.
AC   Q6NYC8; A2AB01; A2AIB8; A4UBI6; A6NCB7; A8MSS7; B7ZCV7; Q68CK8;
AC   Q6ZUJ6; Q8NDQ4; Q8TF52; Q9BRL9;
DE   RecName: Full=Phostensin;
DE   AltName: Full=Protein phosphatase 1 F-actin cytoskeleton-targeting subunit;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 18;
GN   Name=PPP1R18; Synonyms=HKMT1098, KIAA1949;
//
ID   PPR1A_HUMAN             Reviewed;         171 AA.
AC   Q13522; Q6IB01; Q8TBJ2; Q8WWV2;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 1A;
DE   AltName: Full=Protein phosphatase inhibitor 1;
DE            Short=I-1;
DE            Short=IPP-1;
GN   Name=PPP1R1A; Synonyms=IPP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PPR1B_HUMAN             Reviewed;         204 AA.
AC   Q9UD71; Q547V9; Q547W0; Q9H7G1;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 1B;
DE   AltName: Full=DARPP-32;
DE   AltName: Full=Dopamine- and cAMP-regulated neuronal phosphoprotein;
GN   Name=PPP1R1B; Synonyms=DARPP32;
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0008599; F:protein phosphatase type 1 regulator activity; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007621; P:negative regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   PPR1C_HUMAN             Reviewed;         109 AA.
AC   Q8WVI7; Q5HYJ5; Q8TD54;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 1C;
DE   AltName: Full=Inhibitor-5 of protein phosphatase 1;
DE            Short=IPP5;
GN   Name=PPP1R1C;
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:1900087; P:positive regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   PPR21_HUMAN             Reviewed;         780 AA.
AC   Q6ZMI0; B7ZKY5; B7ZKY7; E1B6W7; Q2TA78; Q6ZMI6; Q8IW83; Q8J029;
AC   Q96ES8;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 21;
DE   AltName: Full=Coiled-coil domain-containing protein 128;
DE   AltName: Full=KLRAQ motif-containing protein 1;
GN   Name=PPP1R21; Synonyms=CCDC128, KLRAQ1;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
//
ID   PPR26_HUMAN             Reviewed;        1209 AA.
AC   Q5T8A7; Q86WU0; Q8WVV0; Q9Y4D3;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 26;
GN   Name=PPP1R26; Synonyms=KIAA0649;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PPR27_HUMAN             Reviewed;         154 AA.
AC   Q86WC6;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 27;
DE   AltName: Full=Dysferlin-interacting protein 1;
DE   AltName: Full=Toonin;
GN   Name=PPP1R27; Synonyms=DYSFIP1;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PPR29_HUMAN             Reviewed;         820 AA.
AC   Q5R3F8; Q96PY3;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 29;
DE   AltName: Full=Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2;
DE   AltName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 6;
DE   AltName: Full=Leucine-rich repeat-containing protein 62;
DE   Flags: Precursor;
GN   Name=ELFN2; Synonyms=KIAA1904, LRRC62, PPP1R29;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PPR32_HUMAN             Reviewed;         425 AA.
AC   Q7Z5V6; Q4G0P4; Q96M77;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 32;
GN   Name=PPP1R32; Synonyms=C11orf66;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PPR36_HUMAN             Reviewed;         422 AA.
AC   Q96LQ0; Q6NTH6;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 36;
GN   Name=PPP1R36; Synonyms=C14orf50;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PPR35_HUMAN             Reviewed;         253 AA.
AC   Q8TAP8; A4D2C5;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 35;
GN   Name=PPP1R35; Synonyms=C7orf47;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PPR37_HUMAN             Reviewed;         691 AA.
AC   O75864; B5MDA4; Q8IWK3; Q8TF16;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 37;
DE   AltName: Full=Leucine-rich repeat-containing protein 68;
GN   Name=PPP1R37; Synonyms=KIAA1986, LRRC68;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   PPR3A_HUMAN             Reviewed;        1122 AA.
AC   Q16821; A0AVQ2; A4D0T6; O43476; Q75LN8; Q7KYM8; Q86UI6;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3A;
DE   AltName: Full=Protein phosphatase 1 glycogen-associated regulatory subunit;
DE   AltName: Full=Protein phosphatase type-1 glycogen targeting subunit;
DE            Short=RG1;
GN   Name=PPP1R3A; Synonyms=PP1G;
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
//
ID   PPR3B_HUMAN             Reviewed;         285 AA.
AC   Q86XI6; B3KTV3; Q9H812;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3B;
DE   AltName: Full=Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 4;
DE            Short=PP1 subunit R4;
DE   AltName: Full=Protein phosphatase 1 subunit GL;
DE            Short=PTG;
GN   Name=PPP1R3B; Synonyms=PPP1R4;
DR   GO; GO:0019888; F:protein phosphatase regulator activity; IEA:Ensembl.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0005981; P:regulation of glycogen catabolic process; IDA:MGI.
//
ID   PPR3C_HUMAN             Reviewed;         317 AA.
AC   Q9UQK1; B2R7X0; O95686;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3C;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 5;
DE            Short=PP1 subunit R5;
DE   AltName: Full=Protein targeting to glycogen;
DE            Short=PTG;
GN   Name=PPP1R3C; Synonyms=PPP1R5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PPR3D_HUMAN             Reviewed;         299 AA.
AC   O95685; Q6DK02;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3D;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 6;
DE            Short=PP1 subunit R6;
DE   AltName: Full=Protein phosphatase 1-binding subunit R6;
GN   Name=PPP1R3D; Synonyms=PPP1R6;
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0005981; P:regulation of glycogen catabolic process; IEA:Ensembl.
//
ID   PPR3E_HUMAN             Reviewed;         279 AA.
AC   Q9H7J1; D3DS47;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3E;
GN   Name=PPP1R3E;
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
//
ID   PPR3F_HUMAN             Reviewed;         799 AA.
AC   Q6ZSY5; A2VDJ8; B3KPW2; E9PCM3;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 3F;
DE            Short=R3F;
GN   Name=PPP1R3F;
DR   GO; GO:2001069; F:glycogen binding; IDA:MGI.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:MGI.
DR   GO; GO:2000465; P:regulation of glycogen (starch) synthase activity; IDA:MGI.
DR   GO; GO:0005979; P:regulation of glycogen biosynthetic process; IDA:MGI.
//
ID   PPR42_HUMAN             Reviewed;         355 AA.
AC   Q7Z4L9;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 42;
DE   AltName: Full=Leucine-rich repeat-containing protein 67;
GN   Name=PPP1R42; Synonyms=LRRC67;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0045502; F:dynein binding; ISS:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0010921; P:regulation of phosphatase activity; IEA:Ensembl.
//
ID   PPRC1_HUMAN             Reviewed;        1664 AA.
AC   Q5VV67; Q5VV66; Q6P3U5; Q6P3W1; Q76N31; Q9BUJ3; Q9BZE5; Q9Y4E0;
DE   RecName: Full=Peroxisome proliferator-activated receptor gamma coactivator-related protein 1;
DE   AltName: Full=PGC-1-related coactivator;
DE            Short=PRC;
GN   Name=PPRC1; Synonyms=KIAA0595;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PPT1_HUMAN              Reviewed;         306 AA.
AC   P50897; B4DY24; Q6FGQ4;
DE   RecName: Full=Palmitoyl-protein thioesterase 1;
DE            Short=PPT-1;
DE            EC=3.1.2.22;
DE   AltName: Full=Palmitoyl-protein hydrolase 1;
DE   Flags: Precursor;
GN   Name=PPT1; Synonyms=PPT;
DR   GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IDA:UniProtKB.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0044257; P:cellular protein catabolic process; IEA:Ensembl.
DR   GO; GO:0051186; P:cofactor metabolic process; IMP:UniProtKB.
DR   GO; GO:0051181; P:cofactor transport; IMP:UniProtKB.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0016042; P:lipid catabolic process; IDA:UniProtKB.
DR   GO; GO:0007042; P:lysosomal lumen acidification; IMP:UniProtKB.
DR   GO; GO:0031579; P:membrane raft organization; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0048666; P:neuron development; TAS:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0006907; P:pinocytosis; IMP:MGI.
DR   GO; GO:0048549; P:positive regulation of pinocytosis; IMP:UniProtKB.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0002084; P:protein depalmitoylation; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:MGI.
DR   GO; GO:0032429; P:regulation of phospholipase A2 activity; IEA:Ensembl.
DR   GO; GO:0050803; P:regulation of synapse structure and activity; NAS:UniProtKB.
DR   GO; GO:0030149; P:sphingolipid catabolic process; TAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   PPT2_HUMAN              Reviewed;         302 AA.
AC   Q9UMR5; A2ABC9; A2ABD1; A2ARM7; A2BFH7; A2BFH9; A2BFI2; A8K9L4;
AC   B0S868; G8JLE1; O14799; Q0P6K0; Q5JP13; Q5JP14; Q5JQF0; Q5SSX4;
AC   Q5SSX5; Q5SSX6; Q5STJ4; Q5STJ5; Q5STJ6; Q6FI80; Q99945;
DE   RecName: Full=Lysosomal thioesterase PPT2;
DE            Short=PPT-2;
DE            EC=3.1.2.-;
DE   AltName: Full=S-thioesterase G14;
DE   Flags: Precursor;
GN   Name=PPT2;
DR   GO; GO:0008474; F:palmitoyl-(protein) hydrolase activity; NAS:UniProtKB.
DR   GO; GO:0016790; F:thiolester hydrolase activity; NAS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
//
ID   PPTC7_HUMAN             Reviewed;         304 AA.
AC   Q8NI37; B3KWC5; Q68DZ7; Q6UY82;
DE   RecName: Full=Protein phosphatase PTC7 homolog;
DE            EC=3.1.3.16;
DE   AltName: Full=T-cell activation protein phosphatase 2C;
DE            Short=TA-PP2C;
DE   AltName: Full=T-cell activation protein phosphatase 2C-like;
GN   Name=PPTC7; Synonyms=TAPP2C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
//
ID   PPWD1_HUMAN             Reviewed;         646 AA.
AC   Q96BP3; Q15002; Q7KZ89;
DE   RecName: Full=Peptidylprolyl isomerase domain and WD repeat-containing protein 1;
DE            EC=5.2.1.8;
DE   AltName: Full=Spliceosome-associated cyclophilin;
GN   Name=PPWD1; Synonyms=KIAA0073;
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
//
ID   PPY2_HUMAN              Reviewed;          21 AA.
AC   Q9NRI7;
DE   RecName: Full=Putative pancreatic polypeptide 2;
GN   Name=PPY2;
//
ID   PQBP1_HUMAN             Reviewed;         265 AA.
AC   O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35;
AC   Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4;
DE   RecName: Full=Polyglutamine-binding protein 1;
DE            Short=PQBP-1;
DE   AltName: Full=38 kDa nuclear protein containing a WW domain;
DE            Short=Npw38;
DE   AltName: Full=Polyglutamine tract-binding protein 1;
GN   Name=PQBP1; Synonyms=NPW38; ORFNames=JM26;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:MGI.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0043484; P:regulation of RNA splicing; IMP:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PQLC3_HUMAN             Reviewed;         202 AA.
AC   Q8N755; B2R8K1; B4DWA4;
DE   RecName: Full=PQ-loop repeat-containing protein 3;
DE   Flags: Precursor;
GN   Name=PQLC3; Synonyms=C2orf22;
//
ID   PQLC1_HUMAN             Reviewed;         271 AA.
AC   Q8N2U9; B7Z7D9; G5E989; Q9H6D0;
DE   RecName: Full=PQ-loop repeat-containing protein 1;
GN   Name=PQLC1;
//
ID   PR14L_HUMAN             Reviewed;        2151 AA.
AC   Q5THK1; Q5THK4; Q6ZNN1; Q6ZWH0; Q8IW74; Q9H5T4;
DE   RecName: Full=Protein PRR14L;
DE   AltName: Full=Proline rich 14-like protein;
GN   Name=PRR14L; Synonyms=C22orf30;
//
ID   PR15A_HUMAN             Reviewed;         674 AA.
AC   O75807; Q6IA96; Q9NVU6;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 15A;
DE   AltName: Full=Growth arrest and DNA damage-inducible protein GADD34;
DE   AltName: Full=Myeloid differentiation primary response protein MyD116 homolog;
GN   Name=PPP1R15A; Synonyms=GADD34;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   PR15B_HUMAN             Reviewed;         713 AA.
AC   Q5SWA1; Q53GQ4; Q658M2; Q6P156; Q96SN1;
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 15B;
GN   Name=PPP1R15B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006983; P:ER overload response; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
//
ID   PR15L_HUMAN             Reviewed;         103 AA.
AC   Q9BU68; D3DTU0;
DE   RecName: Full=Proline-rich protein 15-like protein;
DE   AltName: Full=Protein ATAD4;
GN   Name=PRR15L; Synonyms=ATAD4;
//
ID   PR20D_HUMAN             Reviewed;         221 AA.
AC   P86480; Q8N7V5;
DE   RecName: Full=Proline-rich protein 20D;
GN   Name=PRR20D;
//
ID   PR20E_HUMAN             Reviewed;         221 AA.
AC   P86478; Q8N7V5;
DE   RecName: Full=Proline-rich protein 20E;
GN   Name=PRR20E;
//
ID   PR23B_HUMAN             Reviewed;         265 AA.
AC   Q6ZRT6; B2RNV9;
DE   RecName: Full=Proline-rich protein 23B;
GN   Name=PRR23B;
//
ID   PR20C_HUMAN             Reviewed;         221 AA.
AC   P86479; Q8N7V5;
DE   RecName: Full=Proline-rich protein 20C;
GN   Name=PRR20C;
//
ID   PR23A_HUMAN             Reviewed;         266 AA.
AC   A6NEV1;
DE   RecName: Full=Proline-rich protein 23A;
GN   Name=PRR23A;
//
ID   PR23C_HUMAN             Reviewed;         262 AA.
AC   Q6ZRP0;
DE   RecName: Full=Proline-rich protein 23C;
GN   Name=PRR23C;
//
ID   PR20A_HUMAN             Reviewed;         221 AA.
AC   P86496; Q8N7V5;
DE   RecName: Full=Proline-rich protein 20A;
GN   Name=PRR20A; Synonyms=PRR20;
//
ID   PR20B_HUMAN             Reviewed;         221 AA.
AC   P86481; Q8N7V5;
DE   RecName: Full=Proline-rich protein 20B;
GN   Name=PRR20B;
//
ID   PR38A_HUMAN             Reviewed;         312 AA.
AC   Q8NAV1; Q96JW1; Q9BVZ8;
DE   RecName: Full=Pre-mRNA-splicing factor 38A;
GN   Name=PRPF38A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PR38B_HUMAN             Reviewed;         546 AA.
AC   Q5VTL8; Q05DD6; Q32Q58; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9;
AC   Q9NW40;
DE   RecName: Full=Pre-mRNA-splicing factor 38B;
DE   AltName: Full=Sarcoma antigen NY-SAR-27;
GN   Name=PRPF38B;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PR40A_HUMAN             Reviewed;         957 AA.
AC   O75400; O43856; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8;
DE   RecName: Full=Pre-mRNA-processing factor 40 homolog A;
DE   AltName: Full=Fas ligand-associated factor 1;
DE   AltName: Full=Formin-binding protein 11;
DE   AltName: Full=Formin-binding protein 3;
DE   AltName: Full=Huntingtin yeast partner A;
DE   AltName: Full=Huntingtin-interacting protein 10;
DE            Short=HIP-10;
DE   AltName: Full=Huntingtin-interacting protein A;
DE   AltName: Full=Renal carcinoma antigen NY-REN-6;
GN   Name=PRPF40A; Synonyms=FBP11, FLAF1, FNBP3, HIP10, HYPA;
GN   ORFNames=HSPC225;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PR40B_HUMAN             Reviewed;         871 AA.
AC   Q6NWY9; O75401; Q6PI09; Q6ZWB3; Q8NCZ1; Q9H5G4; Q9NT95;
DE   RecName: Full=Pre-mRNA-processing factor 40 homolog B;
DE   AltName: Full=Huntingtin yeast partner C;
DE   AltName: Full=Huntingtin-interacting protein C;
GN   Name=PRPF40B; Synonyms=HYPC;
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PRA13_HUMAN             Reviewed;         474 AA.
AC   Q5VWM6;
DE   RecName: Full=PRAME family member 13;
GN   Name=PRAMEF13;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA10_HUMAN             Reviewed;         474 AA.
AC   O60809; Q2M1V2;
DE   RecName: Full=PRAME family member 10;
GN   Name=PRAMEF10;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA16_HUMAN             Reviewed;         474 AA.
AC   Q5VWM1;
DE   RecName: Full=PRAME family member 16;
GN   Name=PRAMEF16;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA17_HUMAN             Reviewed;         474 AA.
AC   Q5VTA0; B2RUU4;
DE   RecName: Full=PRAME family member 17;
GN   Name=PRAMEF17;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA11_HUMAN             Reviewed;         436 AA.
AC   O60813;
DE   RecName: Full=PRAME family member 11;
GN   Name=PRAMEF11;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA12_HUMAN             Reviewed;         483 AA.
AC   O95522;
DE   RecName: Full=PRAME family member 12;
GN   Name=PRAMEF12;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA19_HUMAN             Reviewed;         410 AA.
AC   Q5SWL8;
DE   RecName: Full=PRAME family member 19;
GN   Name=PRAMEF19;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA14_HUMAN             Reviewed;         426 AA.
AC   Q5SWL7;
DE   RecName: Full=PRAME family member 14;
GN   Name=PRAMEF14;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA18_HUMAN             Reviewed;         479 AA.
AC   Q5VWM3;
DE   RecName: Full=PRAME family member 18;
GN   Name=PRAMEF18;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA20_HUMAN             Reviewed;         475 AA.
AC   Q5VT98;
DE   RecName: Full=PRAME family member 20/21;
GN   Name=PRAMEF20;
GN   and
GN   Name=PRAMEF21;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA22_HUMAN             Reviewed;         481 AA.
AC   A3QJZ6; A6NMM3;
DE   RecName: Full=PRAME family member 22;
GN   Name=PRAMEF22;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA23_HUMAN             Reviewed;         476 AA.
AC   A6NMV5;
DE   RecName: Full=PRAME family member 23;
GN   Name=PRAMEF23;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA24_HUMAN             Reviewed;         474 AA.
AC   A6NMC2;
DE   RecName: Full=Putative PRAME family member 24;
GN   Name=PRAMEF24;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRA25_HUMAN             Reviewed;         474 AA.
AC   A6NGN4;
DE   RecName: Full=Putative PRAME family member 25;
GN   Name=PRAMEF25;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAF1_HUMAN             Reviewed;         185 AA.
AC   Q9UI14; Q7Z4Y2; Q9Y3R1;
DE   RecName: Full=Prenylated Rab acceptor protein 1;
DE   AltName: Full=PRA1 family protein 1;
GN   Name=RABAC1; Synonyms=PRA1, PRAF1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   PRAC1_HUMAN             Reviewed;          57 AA.
AC   Q96KF2;
DE   RecName: Full=Small nuclear protein PRAC1;
DE   AltName: Full=Prostate cancer susceptibility candidate protein 1;
DE   AltName: Full=Prostate, rectum and colon expressed gene protein;
GN   Name=PRAC1; Synonyms=C17orf92, PRAC;
//
ID   PRA26_HUMAN             Reviewed;         382 AA.
AC   H0Y7S4;
DE   RecName: Full=Putative PRAME family member 26;
GN   Name=PRAMEF26;
//
ID   PRAF2_HUMAN             Reviewed;         178 AA.
AC   O60831; B2RD20;
DE   RecName: Full=PRA1 family protein 2;
GN   Name=PRAF2; ORFNames=JM4;
DR   GO; GO:0015813; P:L-glutamate transport; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   PRAF3_HUMAN             Reviewed;         188 AA.
AC   O75915; B2R6V5; Q53ES3; Q5KU08;
DE   RecName: Full=PRA1 family protein 3;
DE   AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 5;
DE            Short=ARL-6-interacting protein 5;
DE            Short=Aip-5;
DE   AltName: Full=Cytoskeleton-related vitamin A-responsive protein;
DE   AltName: Full=Dermal papilla-derived protein 11;
DE   AltName: Full=GTRAP3-18;
DE   AltName: Full=Glutamate transporter EAAC1-interacting protein;
DE   AltName: Full=JM5;
DE   AltName: Full=Prenylated Rab acceptor protein 2;
DE   AltName: Full=Protein JWa;
DE   AltName: Full=Putative MAPK-activating protein PM27;
GN   Name=ARL6IP5; Synonyms=DERP11, JWA, PRA2, PRAF3; ORFNames=HSPC127;
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IDA:UniProt.
DR   GO; GO:0015813; P:L-glutamate transport; ISS:UniProtKB.
DR   GO; GO:0010917; P:negative regulation of mitochondrial membrane potential; IMP:UniProt.
DR   GO; GO:0051051; P:negative regulation of transport; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProt.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProt.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:UniProt.
//
ID   PRAM1_HUMAN             Reviewed;         474 AA.
AC   O95521; Q9UQP2;
DE   RecName: Full=PRAME family member 1;
GN   Name=PRAMEF1;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM2_HUMAN             Reviewed;         474 AA.
AC   O60811;
DE   RecName: Full=PRAME family member 2;
GN   Name=PRAMEF2;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM3_HUMAN             Reviewed;         479 AA.
AC   Q5TYW8;
DE   RecName: Full=PRAME family member 3;
GN   Name=PRAMEF3;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM4_HUMAN             Reviewed;         478 AA.
AC   O60810; Q5LJB5;
DE   RecName: Full=PRAME family member 4;
GN   Name=PRAMEF4;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM6_HUMAN             Reviewed;         476 AA.
AC   Q5VXH4; A0AUJ9;
DE   RecName: Full=PRAME family member 6;
GN   Name=PRAMEF6;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM5_HUMAN             Reviewed;         476 AA.
AC   Q5TYX0; A2BDD6; A4FU31;
DE   RecName: Full=PRAME family member 5;
GN   Name=PRAMEF5;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM7_HUMAN             Reviewed;         474 AA.
AC   Q5VXH5; B9EIP0;
DE   RecName: Full=PRAME family member 7;
GN   Name=PRAMEF7;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM8_HUMAN             Reviewed;         474 AA.
AC   Q5VWM4;
DE   RecName: Full=PRAME family member 8;
GN   Name=PRAMEF8;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAM9_HUMAN             Reviewed;         478 AA.
AC   Q5VWM5; B2RPE1; Q08EQ1;
DE   RecName: Full=PRAME family member 9/15;
GN   Name=PRAMEF9;
GN   and
GN   Name=PRAMEF15;
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro.
//
ID   PRAME_HUMAN             Reviewed;         509 AA.
AC   P78395; B2R6Y7; O43481; Q8IXN8;
DE   RecName: Full=Melanoma antigen preferentially expressed in tumors;
DE   AltName: Full=Opa-interacting protein 4;
DE            Short=OIP-4;
DE   AltName: Full=Preferentially expressed antigen of melanoma;
GN   Name=PRAME; Synonyms=MAPE, OIP4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IDA:UniProtKB.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRAM_HUMAN              Reviewed;         718 AA.
AC   Q96QH2; Q8N6W7;
DE   RecName: Full=PML-RARA-regulated adapter molecule 1;
DE            Short=PRAM;
DE            Short=PRAM-1;
GN   Name=PRAM1;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0043313; P:regulation of neutrophil degranulation; IEA:Ensembl.
//
ID   PRAP1_HUMAN             Reviewed;         151 AA.
AC   Q96NZ9; B7ZL57; B7ZL58; E9KL31; Q5VWY4; Q7Z4X5; Q8IWR3; Q8NCS2;
DE   RecName: Full=Proline-rich acidic protein 1;
DE   AltName: Full=Epididymis tissue protein Li 178;
DE   AltName: Full=Uterine-specific proline-rich acidic protein;
DE   Flags: Precursor;
GN   Name=PRAP1; Synonyms=UPA; ORFNames=UNQ608/PRO1195;
//
ID   PRAX_HUMAN              Reviewed;        1461 AA.
AC   Q9BXM0; Q9BXL9; Q9HCF2;
DE   RecName: Full=Periaxin;
GN   Name=PRX; Synonyms=KIAA1620;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008366; P:axon ensheathment; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   PRB2_HUMAN              Reviewed;         416 AA.
AC   P02812; O00599; P02811; P04281;
DE   RecName: Full=Basic salivary proline-rich protein 2;
DE            Short=Salivary proline-rich protein;
DE   AltName: Full=Con1 glycoprotein;
DE   Contains:
DE     RecName: Full=Basic proline-rich peptide IB-1;
DE   Contains:
DE     RecName: Full=Basic proline-rich peptide P-E;
DE     AltName: Full=IB-9;
DE   Contains:
DE     RecName: Full=Basic proline-rich peptide IB-7;
DE   Contains:
DE     RecName: Full=Basic proline-rich peptide IB-8c;
DE     AltName: Full=Basic peptide P-F;
DE   Contains:
DE     RecName: Full=Basic proline-rich peptide IB-4;
DE   Flags: Precursor;
GN   Name=PRB2;
//
ID   PRB3_HUMAN              Reviewed;         309 AA.
AC   Q04118; Q15188; Q4VAY3; Q4VAY4; Q7M4M9; Q9UCT9;
DE   RecName: Full=Basic salivary proline-rich protein 3;
DE   AltName: Full=Parotid salivary glycoprotein G1;
DE   AltName: Full=Proline-rich protein G1;
DE   Flags: Precursor;
GN   Name=PRB3;
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; NAS:UniProtKB.
//
ID   PRB4_HUMAN              Reviewed;         310 AA.
AC   P10163; A1L439; O00600; P02813; P10161; P10162; P81489;
DE   RecName: Full=Basic salivary proline-rich protein 4;
DE            Short=Salivary proline-rich protein Po;
DE   AltName: Full=Parotid o protein;
DE   AltName: Full=Salivary proline-rich protein II-1;
DE   Contains:
DE     RecName: Full=Protein N1;
DE   Contains:
DE     RecName: Full=Glycosylated protein A;
DE   Contains:
DE     RecName: Full=Peptide P-D;
DE     AltName: Full=Proline-rich peptide IB-5;
DE   Flags: Precursor;
GN   Name=PRB4;
//
ID   PRC1_HUMAN              Reviewed;         620 AA.
AC   O43663; A6NC44; B4DLR1; H9KV59; Q9BSB6;
DE   RecName: Full=Protein regulator of cytokinesis 1;
GN   Name=PRC1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0000022; P:mitotic spindle elongation; TAS:ProtInc.
//
ID   PRC2A_HUMAN             Reviewed;        2157 AA.
AC   P48634; B0UX77; B0UZE9; B0UZL3; O95875; Q05BK4; Q4LE37; Q5SQ29;
AC   Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9;
AC   Q96QC6;
DE   RecName: Full=Protein PRRC2A;
DE   AltName: Full=HLA-B-associated transcript 2;
DE   AltName: Full=Large proline-rich protein BAT2;
DE   AltName: Full=Proline-rich and coiled-coil-containing protein 2A;
DE   AltName: Full=Protein G2;
GN   Name=PRRC2A; Synonyms=BAT2, G2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PRC2B_HUMAN             Reviewed;        2229 AA.
AC   Q5JSZ5; O60270; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683;
DE   RecName: Full=Protein PRRC2B;
DE   AltName: Full=HLA-B-associated transcript 2-like 1;
DE   AltName: Full=Proline-rich coiled-coil protein 2B;
GN   Name=PRRC2B; Synonyms=BAT2L, BAT2L1, KIAA0515;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PRC2C_HUMAN             Reviewed;        2896 AA.
AC   Q9Y520; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3;
AC   Q9UF29; Q9UPQ6;
DE   RecName: Full=Protein PRRC2C;
DE   AltName: Full=BAT2 domain-containing protein 1;
DE   AltName: Full=HBV X-transactivated gene 2 protein;
DE   AltName: Full=HBV XAg-transactivated protein 2;
DE   AltName: Full=HLA-B-associated transcript 2-like 2;
DE   AltName: Full=Proline-rich and coiled-coil-containing protein 2C;
GN   Name=PRRC2C; Synonyms=BAT2D1, BAT2L2, KIAA1096, XTP2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
//
ID   PRCA1_HUMAN             Reviewed;         364 AA.
AC   Q8NCQ7; B4DX95; G5E9R8;
DE   RecName: Full=Protein PROCA1;
GN   Name=PROCA1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:InterPro.
//
ID   PRCC_HUMAN              Reviewed;         491 AA.
AC   Q92733; A8K1F7; O00665; O00724; Q5SZ06;
DE   RecName: Full=Proline-rich protein PRCC;
DE   AltName: Full=Papillary renal cell carcinoma translocation-associated gene protein;
GN   Name=PRCC; Synonyms=TPRC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:UniProtKB.
//
ID   PRCD_HUMAN              Reviewed;          54 AA.
AC   Q00LT1; B9EJD4;
DE   RecName: Full=Progressive rod-cone degeneration protein;
GN   Name=PRCD;
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   PRD10_HUMAN             Reviewed;        1147 AA.
AC   Q9NQV6; B7ZL71; G3XAE5; J3KP23; Q17R90; Q2KHR4; Q863Z2; Q9NXI4;
AC   Q9ULI9;
DE   RecName: Full=PR domain zinc finger protein 10;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 10;
DE   AltName: Full=Tristanin;
GN   Name=PRDM10; Synonyms=KIAA1231, PFM7, TRIS;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRD11_HUMAN             Reviewed;         511 AA.
AC   Q9NQV5; Q8N9F1;
DE   RecName: Full=PR domain-containing protein 11;
DE            EC=2.1.1.-;
GN   Name=PRDM11; Synonyms=PFM8;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   PRD12_HUMAN             Reviewed;         367 AA.
AC   Q9H4Q4; A3KFK9;
DE   RecName: Full=PR domain zinc finger protein 12;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 12;
GN   Name=PRDM12; Synonyms=PFM9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRD13_HUMAN             Reviewed;         707 AA.
AC   Q9H4Q3; Q5TGC1; Q5TGC2;
DE   RecName: Full=PR domain zinc finger protein 13;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 13;
GN   Name=PRDM13; Synonyms=PFM10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRD14_HUMAN             Reviewed;         571 AA.
AC   Q9GZV8; Q86UX9;
DE   RecName: Full=PR domain zinc finger protein 14;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 14;
GN   Name=PRDM14;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRD15_HUMAN             Reviewed;        1507 AA.
AC   P57071; Q8N0X3; Q8NEX0; Q9NQV3;
DE   RecName: Full=PR domain zinc finger protein 15;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 15;
DE   AltName: Full=Zinc finger protein 298;
GN   Name=PRDM15; Synonyms=C21orf83, ZNF298;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRD16_HUMAN             Reviewed;        1276 AA.
AC   Q9HAZ2; A6NHQ8; B1AJP7; B1AJP8; B1AJP9; B1WB48; Q8WYJ9; Q9C0I8;
DE   RecName: Full=PR domain zinc finger protein 16;
DE   AltName: Full=PR domain-containing protein 16;
DE   AltName: Full=Transcription factor MEL1;
DE            Short=MDS1/EVI1-like gene 1;
GN   Name=PRDM16; Synonyms=KIAA1675, MEL1, PFM13;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030853; P:negative regulation of granulocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043457; P:regulation of cellular respiration; ISS:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0050872; P:white fat cell differentiation; IEA:Ensembl.
//
ID   PRDBP_HUMAN             Reviewed;         261 AA.
AC   Q969G5;
DE   RecName: Full=Protein kinase C delta-binding protein;
DE   AltName: Full=Cavin-3;
DE   AltName: Full=Serum deprivation response factor-related gene product that binds to C-kinase;
DE            Short=hSRBC;
GN   Name=PRKCDBP; Synonyms=SRBC;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PRDC1_HUMAN             Reviewed;         225 AA.
AC   Q9NRG1; B7Z1Z3; Q53HA7; Q59EL9; Q5VV18; Q5VV20;
DE   RecName: Full=Phosphoribosyltransferase domain-containing protein 1;
GN   Name=PRTFDC1; Synonyms=HHGP;
DR   GO; GO:0000287; F:magnesium ion binding; TAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
//
ID   PRDM2_HUMAN             Reviewed;        1718 AA.
AC   Q13029; B1AJZ4; B5MC68; Q13149; Q14550; Q5THJ1; Q5VUL9;
DE   RecName: Full=PR domain zinc finger protein 2;
DE            EC=2.1.1.43;
DE   AltName: Full=GATA-3-binding protein G3B;
DE   AltName: Full=Lysine N-methyltransferase 8;
DE   AltName: Full=MTB-ZF;
DE   AltName: Full=MTE-binding protein;
DE   AltName: Full=PR domain-containing protein 2;
DE   AltName: Full=Retinoblastoma protein-interacting zinc finger protein;
DE   AltName: Full=Zinc finger protein RIZ;
GN   Name=PRDM2; Synonyms=KMT8, RIZ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRDM1_HUMAN             Reviewed;         825 AA.
AC   O75626; B2REA6; E1P5E0; Q86WM7;
DE   RecName: Full=PR domain zinc finger protein 1;
DE            EC=2.1.1.-;
DE   AltName: Full=BLIMP-1;
DE   AltName: Full=Beta-interferon gene positive regulatory domain I-binding factor;
DE   AltName: Full=PR domain-containing protein 1;
DE   AltName: Full=Positive regulatory domain I-binding factor 1;
DE            Short=PRDI-BF1;
DE            Short=PRDI-binding factor 1;
GN   Name=PRDM1; Synonyms=BLIMP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
//
ID   PRDM4_HUMAN             Reviewed;         801 AA.
AC   Q9UKN5; Q9UFA6;
DE   RecName: Full=PR domain zinc finger protein 4;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 4;
GN   Name=PRDM4; Synonyms=PFM1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PRDM5_HUMAN             Reviewed;         630 AA.
AC   Q9NQX1; Q0VAI9; Q0VAJ0; Q6NXQ7;
DE   RecName: Full=PR domain zinc finger protein 5;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 5;
GN   Name=PRDM5; Synonyms=PFM2;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0016575; P:histone deacetylation; IMP:UniProtKB.
DR   GO; GO:0051567; P:histone H3-K9 methylation; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRDM6_HUMAN             Reviewed;         595 AA.
AC   Q9NQX0; B5MCJ4; Q9NQW9;
DE   RecName: Full=Putative histone-lysine N-methyltransferase PRDM6;
DE            EC=2.1.1.43;
DE   AltName: Full=PR domain zinc finger protein 6;
DE   AltName: Full=PR domain-containing protein 6;
GN   Name=PRDM6; Synonyms=PFM3;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0051151; P:negative regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRDM7_HUMAN             Reviewed;         492 AA.
AC   Q9NQW5; A4Q9G8; Q08EM4; Q9NQW4;
DE   RecName: Full=Probable histone-lysine N-methyltransferase PRDM7;
DE            EC=2.1.1.43;
DE   AltName: Full=PR domain zinc finger protein 7;
DE   AltName: Full=PR domain-containing protein 7;
GN   Name=PRDM7; Synonyms=PFM4;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   PRDM8_HUMAN             Reviewed;         689 AA.
AC   Q9NQV8; A8K7X2; Q6IQ36;
DE   RecName: Full=PR domain zinc finger protein 8;
DE            EC=2.1.1.-;
DE   AltName: Full=PR domain-containing protein 8;
GN   Name=PRDM8; Synonyms=PFM5;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0021540; P:corpus callosum morphogenesis; IEA:Ensembl.
DR   GO; GO:0021957; P:corticospinal tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRDM9_HUMAN             Reviewed;         894 AA.
AC   Q9NQV7; B4DX22; Q27Q50;
DE   RecName: Full=Histone-lysine N-methyltransferase PRDM9;
DE            EC=2.1.1.43;
DE   AltName: Full=PR domain zinc finger protein 9;
DE   AltName: Full=PR domain-containing protein 9;
GN   Name=PRDM9; Synonyms=PFM6;
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0010844; F:recombination hotspot binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0006311; P:meiotic gene conversion; IDA:MGI.
DR   GO; GO:0060903; P:positive regulation of meiosis I; IEA:Ensembl.
DR   GO; GO:0010845; P:positive regulation of reciprocal meiotic recombination; IMP:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRDX1_HUMAN             Reviewed;         199 AA.
AC   Q06830; B5BU26; D3DPZ8; P35703; Q2V576; Q5T154; Q5T155;
DE   RecName: Full=Peroxiredoxin-1;
DE            EC=1.11.1.15;
DE   AltName: Full=Natural killer cell-enhancing factor A;
DE            Short=NKEF-A;
DE   AltName: Full=Proliferation-associated gene protein;
DE            Short=PAG;
DE   AltName: Full=Thioredoxin peroxidase 2;
DE   AltName: Full=Thioredoxin-dependent peroxide reductase 2;
GN   Name=PRDX1; Synonyms=PAGA, PAGB, TDPX2;
DR   GO; GO:0020037; F:heme binding; IEA:Ensembl.
DR   GO; GO:0004601; F:peroxidase activity; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008379; F:thioredoxin peroxidase activity; IDA:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:BHF-UCL.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0042345; P:regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0032872; P:regulation of stress-activated MAPK cascade; IEA:Ensembl.
DR   GO; GO:0019430; P:removal of superoxide radicals; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   PRDX2_HUMAN             Reviewed;         198 AA.
AC   P32119; A8K0C0; P31945; P32118; P35701; Q6FHG4; Q92763; Q9UC23;
DE   RecName: Full=Peroxiredoxin-2;
DE            EC=1.11.1.15;
DE   AltName: Full=Natural killer cell-enhancing factor B;
DE            Short=NKEF-B;
DE   AltName: Full=PRP;
DE   AltName: Full=Thiol-specific antioxidant protein;
DE            Short=TSA;
DE   AltName: Full=Thioredoxin peroxidase 1;
DE   AltName: Full=Thioredoxin-dependent peroxide reductase 1;
GN   Name=PRDX2; Synonyms=NKEFB, TDPX1;
DR   GO; GO:0016209; F:antioxidant activity; IDA:UniProtKB.
DR   GO; GO:0008379; F:thioredoxin peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:BHF-UCL.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; TAS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0019430; P:removal of superoxide radicals; IDA:BHF-UCL.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
//
ID   PRDX3_HUMAN             Reviewed;         256 AA.
AC   P30048; B2R7Z0; D3DRC9; E9PH29; P35690; Q0D2H1; Q13776; Q5T5V2;
AC   Q96HK4;
DE   RecName: Full=Thioredoxin-dependent peroxide reductase, mitochondrial;
DE            EC=1.11.1.15;
DE   AltName: Full=Antioxidant protein 1;
DE            Short=AOP-1;
DE   AltName: Full=HBC189;
DE   AltName: Full=Peroxiredoxin III;
DE            Short=Prx-III;
DE   AltName: Full=Peroxiredoxin-3;
DE   AltName: Full=Protein MER5 homolog;
DE   Flags: Precursor;
GN   Name=PRDX3; Synonyms=AOP1;
DR   GO; GO:0008785; F:alkyl hydroperoxide reductase activity; NAS:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051920; F:peroxiredoxin activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IMP:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IMP:UniProtKB.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:GOC.
DR   GO; GO:0033673; P:negative regulation of kinase activity; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IMP:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
//
ID   PRDX4_HUMAN             Reviewed;         271 AA.
AC   Q13162; Q6FHT3;
DE   RecName: Full=Peroxiredoxin-4;
DE            EC=1.11.1.15;
DE   AltName: Full=Antioxidant enzyme AOE372;
DE            Short=AOE37-2;
DE   AltName: Full=Peroxiredoxin IV;
DE            Short=Prx-IV;
DE   AltName: Full=Thioredoxin peroxidase AO372;
DE   AltName: Full=Thioredoxin-dependent peroxide reductase A0372;
DE   Flags: Precursor;
GN   Name=PRDX4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008379; F:thioredoxin peroxidase activity; TAS:ProtInc.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; TAS:ProtInc.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:2000255; P:negative regulation of male germ cell proliferation; IEA:Ensembl.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PRDX5_HUMAN             Reviewed;         214 AA.
AC   P30044; A6NC19; A6NG06; B7ZLJ4; B7ZVW3; Q14CK0; Q6IAF2; Q9UBU5;
AC   Q9UJU4; Q9UKX4;
DE   RecName: Full=Peroxiredoxin-5, mitochondrial;
DE            EC=1.11.1.15;
DE   AltName: Full=Alu corepressor 1;
DE   AltName: Full=Antioxidant enzyme B166;
DE            Short=AOEB166;
DE   AltName: Full=Liver tissue 2D-page spot 71B;
DE   AltName: Full=PLP;
DE   AltName: Full=Peroxiredoxin V;
DE            Short=Prx-V;
DE   AltName: Full=Peroxisomal antioxidant enzyme;
DE   AltName: Full=TPx type VI;
DE   AltName: Full=Thioredoxin peroxidase PMP20;
DE   AltName: Full=Thioredoxin reductase;
DE   Flags: Precursor;
GN   Name=PRDX5; Synonyms=ACR1; ORFNames=SBBI10;
DR   GO; GO:0016209; F:antioxidant activity; IDA:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0051920; F:peroxiredoxin activity; IDA:UniProtKB.
DR   GO; GO:0072541; F:peroxynitrite reductase activity; IDA:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0001016; F:RNA polymerase III regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IMP:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0070995; P:NADPH oxidation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:GOC.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0016480; P:negative regulation of transcription from RNA polymerase III promoter; IDA:UniProtKB.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2001057; P:reactive nitrogen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0060785; P:regulation of apoptosis involved in tissue homeostasis; IDA:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
//
ID   PRDX6_HUMAN             Reviewed;         224 AA.
AC   P30041; A8JZY7; P32077; Q5TAH4; Q5ZEZ8;
DE   RecName: Full=Peroxiredoxin-6;
DE            EC=1.11.1.15;
DE   AltName: Full=1-Cys peroxiredoxin;
DE            Short=1-Cys PRX;
DE   AltName: Full=24 kDa protein;
DE   AltName: Full=Acidic calcium-independent phospholipase A2;
DE            Short=aiPLA2;
DE            EC=3.1.1.-;
DE   AltName: Full=Antioxidant protein 2;
DE   AltName: Full=Liver 2D page spot 40;
DE   AltName: Full=Non-selenium glutathione peroxidase;
DE            Short=NSGPx;
DE            EC=1.11.1.9;
DE   AltName: Full=Red blood cells page spot 12;
GN   Name=PRDX6; Synonyms=AOP2, KIAA0106;
DR   GO; GO:0016209; F:antioxidant activity; NAS:UniProtKB.
DR   GO; GO:0004602; F:glutathione peroxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051920; F:peroxiredoxin activity; IEA:UniProtKB-EC.
DR   GO; GO:0004623; F:phospholipase A2 activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:Ensembl.
DR   GO; GO:0009395; P:phospholipid catabolic process; IDA:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
//
ID   PREB_HUMAN              Reviewed;         417 AA.
AC   Q9HCU5; Q53SZ8; Q9UH94;
DE   RecName: Full=Prolactin regulatory element-binding protein;
DE   AltName: Full=Mammalian guanine nucleotide exchange factor mSec12;
GN   Name=PREB; Synonyms=SEC12;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRELP_HUMAN             Reviewed;         382 AA.
AC   P51888; Q6FG38;
DE   RecName: Full=Prolargin;
DE   AltName: Full=Proline-arginine-rich end leucine-rich repeat protein;
DE   Flags: Precursor;
GN   Name=PRELP; Synonyms=SLRR2A;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042340; P:keratan sulfate catabolic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PREP_HUMAN              Reviewed;        1037 AA.
AC   Q5JRX3; B3KMJ6; B4E0J8; C9JSL2; E7ES23; O95204; Q2M2G6; Q4VBR1;
AC   Q5JRW7; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8;
DE   RecName: Full=Presequence protease, mitochondrial;
DE            Short=hPreP;
DE            EC=3.4.24.-;
DE   AltName: Full=Pitrilysin metalloproteinase 1;
DE            Short=Metalloprotease 1;
DE            Short=hMP1;
DE   Flags: Precursor;
GN   Name=PITRM1; Synonyms=KIAA1104, MP1;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
//
ID   PREX1_HUMAN             Reviewed;        1659 AA.
AC   Q8TCU6; E1P5X9; Q5JS95; Q5JS96; Q69YL2; Q7Z2L9; Q9BQH0; Q9BX55;
AC   Q9H4Q6; Q9P2D2; Q9UGQ4;
DE   RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein;
DE            Short=P-Rex1;
DE            Short=PtdIns(3,4,5)-dependent Rac exchanger 1;
GN   Name=PREX1; Synonyms=KIAA1415;
DR   GO; GO:0019899; F:enzyme binding; TAS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:UniProtKB.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0042119; P:neutrophil activation; TAS:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0050773; P:regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0006801; P:superoxide metabolic process; TAS:UniProtKB.
//
ID   PREX2_HUMAN             Reviewed;        1606 AA.
AC   Q70Z35; Q32KL0; Q32KL1; Q6R7Q3; Q6R7Q4; Q9H805; Q9H961;
DE   RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein;
DE            Short=P-Rex2;
DE            Short=PtdIns(3,4,5)-dependent Rac exchanger 2;
DE   AltName: Full=DEP domain-containing protein 2;
GN   Name=PREX2; Synonyms=DEPDC2;
DR   GO; GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:MGI.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:MGI.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
//
ID   PREY_HUMAN              Reviewed;         114 AA.
AC   Q96I23; B2R571;
DE   RecName: Full=Protein preY, mitochondrial;
DE   AltName: Full=PIGY upstream reading frame protein;
DE   Flags: Precursor;
GN   Name=PYURF; Synonyms=PREY;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IMP:HGNC.
DR   GO; GO:0009893; P:positive regulation of metabolic process; IMP:HGNC.
//
ID   PRG2_HUMAN              Reviewed;         222 AA.
AC   P13727; P81448; Q14227; Q6ICT2;
DE   RecName: Full=Bone marrow proteoglycan;
DE            Short=BMPG;
DE   AltName: Full=Proteoglycan 2;
DE   Contains:
DE     RecName: Full=Eosinophil granule major basic protein;
DE              Short=EMBP;
DE              Short=MBP;
DE     AltName: Full=Pregnancy-associated major basic protein;
DE   Flags: Precursor;
GN   Name=PRG2; Synonyms=MBP;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   PRG3_HUMAN              Reviewed;         225 AA.
AC   Q9Y2Y8;
DE   RecName: Full=Proteoglycan 3;
DE   AltName: Full=Eosinophil major basic protein homolog;
DE   AltName: Full=Prepro-major basic protein homolog;
DE            Short=Prepro-MBPH;
DE   Flags: Precursor;
GN   Name=PRG3; Synonyms=MBPH; ORFNames=UNQ486/PRO1002;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0045575; P:basophil activation; IDA:UniProtKB.
DR   GO; GO:0001694; P:histamine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0042119; P:neutrophil activation; IDA:UniProtKB.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042554; P:superoxide anion generation; IDA:UniProtKB.
//
ID   PRG4_HUMAN              Reviewed;        1404 AA.
AC   Q92954; Q6DNC4; Q6DNC5; Q6ZMZ5; Q9BX49;
DE   RecName: Full=Proteoglycan 4;
DE   AltName: Full=Lubricin;
DE   AltName: Full=Megakaryocyte-stimulating factor;
DE   AltName: Full=Superficial zone proteoglycan;
DE   Contains:
DE     RecName: Full=Proteoglycan 4 C-terminal part;
DE   Flags: Precursor;
GN   Name=PRG4; Synonyms=MSF, SZP;
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
//
ID   PRGC1_HUMAN             Reviewed;         798 AA.
AC   Q9UBK2; B7Z406; G8DM16; I3RTT5; I3RTT6; I3RTT7; I3RTT8; I3RTT9;
AC   Q3LIG1; Q4W5M7; Q9UN32;
DE   RecName: Full=Peroxisome proliferator-activated receptor gamma coactivator 1-alpha;
DE            Short=PGC-1-alpha;
DE            Short=PPAR-gamma coactivator 1-alpha;
DE            Short=PPARGC-1-alpha;
DE   AltName: Full=Ligand effect modulator 6;
GN   Name=PPARGC1A; Synonyms=LEM6, PGC1, PGC1A, PPARGC1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; TAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; TAS:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; TAS:UniProtKB.
DR   GO; GO:0001678; P:cellular glucose homeostasis; NAS:UniProtKB.
DR   GO; GO:0045333; P:cellular respiration; TAS:UniProtKB.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071250; P:cellular response to nitrite; IEA:Ensembl.
DR   GO; GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0007586; P:digestion; TAS:UniProtKB.
DR   GO; GO:0019395; P:fatty acid oxidation; NAS:UniProtKB.
DR   GO; GO:0051552; P:flavone metabolic process; IEA:Ensembl.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:Ensembl.
DR   GO; GO:0006094; P:gluconeogenesis; NAS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; TAS:UniProtKB.
DR   GO; GO:0045820; P:negative regulation of glycolytic process; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:2000272; P:negative regulation of receptor activity; IEA:Ensembl.
DR   GO; GO:0070997; P:neuron death; IDA:UniProtKB.
DR   GO; GO:2001171; P:positive regulation of ATP biosynthetic process; ISS:UniProtKB.
DR   GO; GO:1901857; P:positive regulation of cellular respiration; IEA:Ensembl.
DR   GO; GO:2000507; P:positive regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:0046321; P:positive regulation of fatty acid oxidation; TAS:UniProtKB.
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; TAS:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; TAS:UniProtKB.
DR   GO; GO:1901860; P:positive regulation of mitochondrial DNA metabolic process; IEA:Ensembl.
DR   GO; GO:0010822; P:positive regulation of mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:1901863; P:positive regulation of muscle tissue development; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; TAS:UniProtKB.
DR   GO; GO:0010941; P:regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; ISS:UniProtKB.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0071871; P:response to epinephrine; IEA:Ensembl.
DR   GO; GO:0043201; P:response to leucine; IEA:Ensembl.
DR   GO; GO:0014850; P:response to muscle activity; ISS:BHF-UCL.
DR   GO; GO:0071873; P:response to norepinephrine; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; NAS:UniProtKB.
DR   GO; GO:0036273; P:response to statin; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0001659; P:temperature homeostasis; TAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:UniProtKB.
//
ID   PRGC2_HUMAN             Reviewed;        1023 AA.
AC   Q86YN6; A2RUM8; A2RUN0; B3KVW0; Q86YN3; Q86YN4; Q86YN5; Q8N1N9;
AC   Q8TDE4; Q8TDE5;
DE   RecName: Full=Peroxisome proliferator-activated receptor gamma coactivator 1-beta;
DE            Short=PGC-1-beta;
DE            Short=PPAR-gamma coactivator 1-beta;
DE            Short=PPARGC-1-beta;
DE   AltName: Full=PGC-1-related estrogen receptor alpha coactivator;
GN   Name=PPARGC1B; Synonyms=PERC, PGC1, PGC1B, PPARGC1;
DR   GO; GO:0050682; F:AF-2 domain binding; IPI:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0030546; F:receptor activator activity; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IEA:Ensembl.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:2000273; P:positive regulation of receptor activity; IDA:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   PRGR_HUMAN              Reviewed;         933 AA.
AC   P06401; A7LQ08; A7X8B0; B4E3T0; Q8TDS3; Q9UPF7;
DE   RecName: Full=Progesterone receptor;
DE            Short=PR;
DE   AltName: Full=Nuclear receptor subfamily 3 group C member 3;
GN   Name=PGR; Synonyms=NR3C3;
DR   GuidetoPHARMACOLOGY; 627; -.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0003707; F:steroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0002070; P:epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEP:UniProtKB.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0050847; P:progesterone receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0060748; P:tertiary branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   PRI1_HUMAN              Reviewed;         420 AA.
AC   P49642;
DE   RecName: Full=DNA primase small subunit;
DE            EC=2.7.7.-;
DE   AltName: Full=DNA primase 49 kDa subunit;
DE            Short=p49;
GN   Name=PRIM1;
DR   GO; GO:0003896; F:DNA primase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:Reactome.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; TAS:ProtInc.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
//
ID   PRI2_HUMAN              Reviewed;         509 AA.
AC   P49643; Q53FJ8; Q6P1Q7; Q8WVL2; Q9H413;
DE   RecName: Full=DNA primase large subunit;
DE            EC=2.7.7.-;
DE   AltName: Full=DNA primase 58 kDa subunit;
DE            Short=p58;
GN   Name=PRIM2; Synonyms=PRIM2A;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003896; F:DNA primase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:Reactome.
DR   GO; GO:0006269; P:DNA replication, synthesis of RNA primer; TAS:ProtInc.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
//
ID   PRIC1_HUMAN             Reviewed;         831 AA.
AC   Q96MT3; Q14C83; Q71QF8; Q96N00;
DE   RecName: Full=Prickle-like protein 1;
DE   AltName: Full=REST/NRSF-interacting LIM domain protein 1;
DE   Flags: Precursor;
GN   Name=PRICKLE1; Synonyms=RILP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:2000691; P:negative regulation of cardiac muscle cell myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; IMP:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:UniProtKB.
//
ID   PRIC2_HUMAN             Reviewed;         844 AA.
AC   Q7Z3G6; Q0VF44;
DE   RecName: Full=Prickle-like protein 2;
DE   Flags: Precursor;
GN   Name=PRICKLE2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
//
ID   PRIC3_HUMAN             Reviewed;         615 AA.
AC   O43900; O76007; Q53XR5;
DE   RecName: Full=Prickle-like protein 3;
DE   AltName: Full=LIM domain only protein 6;
DE            Short=LMO-6;
DE   AltName: Full=Triple LIM domain protein 6;
GN   Name=PRICKLE3; Synonyms=LMO6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PRIC4_HUMAN             Reviewed;         344 AA.
AC   Q2TBC4; A2A3M0; A6PVU1; B3KQ15; Q5T3D4; Q9NSV1;
DE   RecName: Full=Prickle-like protein 4;
DE   AltName: Full=Overexpressed breast tumor protein;
GN   Name=PRICKLE4; Synonyms=C6orf49, OEBT;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PRIMA_HUMAN             Reviewed;         153 AA.
AC   Q86XR5; Q86XR6;
DE   RecName: Full=Proline-rich membrane anchor 1;
DE            Short=PRiMA;
DE   Flags: Precursor;
GN   Name=PRIMA1;
DR   GO; GO:0051649; P:establishment of localization in cell; IEA:Ensembl.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW.
//
ID   PRIO_HUMAN              Reviewed;         253 AA.
AC   P04156; O60489; P78446; Q15216; Q15221; Q27H91; Q5QPB4; Q8TBG0;
AC   Q96E70; Q9UP19;
DE   RecName: Full=Major prion protein;
DE            Short=PrP;
DE   AltName: Full=ASCR;
DE   AltName: Full=PrP27-30;
DE   AltName: Full=PrP33-35C;
DE   AltName: CD_antigen=CD230;
DE   Flags: Precursor;
GN   Name=PRNP; Synonyms=PRIP, PRP;
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0070885; P:negative regulation of calcineurin-NFAT signaling cascade; ISS:BHF-UCL.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; ISS:BHF-UCL.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; ISS:BHF-UCL.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
//
ID   PRIPO_HUMAN             Reviewed;         560 AA.
AC   Q96LW4; D3DP55; D6RDM1; Q5HYJ9;
DE   RecName: Full=DNA-directed primase/polymerase protein;
DE            Short=hPrimpol1;
DE            EC=2.7.7.-;
DE   AltName: Full=Coiled-coil domain-containing protein 111;
GN   Name=PRIMPOL; Synonyms=CCDC111;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003896; F:DNA primase activity; IDA:UniProtKB.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; TAS:UniProtKB.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IMP:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0019985; P:translesion synthesis; IMP:UniProtKB.
//
ID   PRKDC_HUMAN             Reviewed;        4128 AA.
AC   P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6;
AC   Q9UME3;
DE   RecName: Full=DNA-dependent protein kinase catalytic subunit;
DE            Short=DNA-PK catalytic subunit;
DE            Short=DNA-PKcs;
DE            EC=2.7.11.1;
DE   AltName: Full=DNPK1;
DE   AltName: Full=p460;
GN   Name=PRKDC; Synonyms=HYRC, HYRC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004677; F:DNA-dependent protein kinase activity; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0002326; P:B cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; TAS:Reactome.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0033152; P:immunoglobulin V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0002328; P:pro-B cell differentiation; IEA:Ensembl.
DR   GO; GO:0031648; P:protein destabilization; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0002360; P:T cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0033153; P:T cell receptor V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; IEA:Ensembl.
//
ID   PRKN2_HUMAN             Reviewed;         465 AA.
AC   O60260; A3FG77; A8K975; D3JZW7; D3K2X0; Q5TFV8; Q5VVX4; Q6Q2I6;
AC   Q8NI41; Q8NI43; Q8NI44; Q8WW07;
DE   RecName: Full=E3 ubiquitin-protein ligase parkin;
DE            EC=6.3.2.-;
DE   AltName: Full=Parkinson juvenile disease protein 2;
DE            Short=Parkinson disease protein 2;
GN   Name=PARK2; Synonyms=PRKN;
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070842; P:aggresome assembly; IMP:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.
DR   GO; GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:BHF-UCL.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:BHF-UCL.
DR   GO; GO:0033132; P:negative regulation of glucokinase activity; IDA:MGI.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IDA:MGI.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.
DR   GO; GO:0070997; P:neuron death; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IDA:UniProtKB.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   PRKRA_HUMAN             Reviewed;         313 AA.
AC   O75569; A8K3I6; Q53G24; Q6X7T5; Q8NDK4;
DE   RecName: Full=Interferon-inducible double-stranded RNA-dependent protein kinase activator A;
DE   AltName: Full=PKR-associated protein X;
DE   AltName: Full=PKR-associating protein X;
DE   AltName: Full=Protein activator of the interferon-induced protein kinase;
DE   AltName: Full=Protein kinase, interferon-inducible double-stranded RNA-dependent activator;
GN   Name=PRKRA; Synonyms=PACT, RAX; ORFNames=HSD-14, HSD14;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042473; P:outer ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0030422; P:production of siRNA involved in RNA interference; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
//
ID   PRKX_HUMAN              Reviewed;         358 AA.
AC   P51817;
DE   RecName: Full=cAMP-dependent protein kinase catalytic subunit PRKX;
DE            Short=PrKX;
DE            Short=Protein kinase X;
DE            Short=Protein kinase X-linked;
DE            Short=Serine/threonine-protein kinase PRKX;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase PKX1;
GN   Name=PRKX; Synonyms=PKX1;
DR   GuidetoPHARMACOLOGY; 2175; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IMP:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IMP:UniProtKB.
DR   GO; GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0060562; P:epithelial tube morphogenesis; IDA:UniProtKB.
DR   GO; GO:0060993; P:kidney morphogenesis; IDA:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; IDA:UniProtKB.
//
ID   PRKY_HUMAN              Reviewed;         277 AA.
AC   O43930; O15348; O15349;
DE   RecName: Full=Putative serine/threonine-protein kinase PRKY;
DE            EC=2.7.11.1;
GN   Name=PRKY;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   PRLD2_HUMAN             Reviewed;         189 AA.
AC   Q8N945; G5EA01; Q96EQ3;
DE   RecName: Full=PRELI domain-containing protein 2;
GN   Name=PRELID2;
DR   GO; GO:1990050; F:phosphatidic acid transporter activity; IBA:RefGenome.
DR   GO; GO:0015914; P:phospholipid transport; IBA:RefGenome.
//
ID   PRLD1_HUMAN             Reviewed;         219 AA.
AC   Q9Y255; B2R5F7; D6RD25; Q549N2; Q9UI13; Q9UJS9;
DE   RecName: Full=PRELI domain-containing protein 1, mitochondrial;
DE   AltName: Full=25 kDa protein of relevant evolutionary and lymphoid interest;
DE   AltName: Full=Px19-like protein;
DE   Flags: Precursor;
GN   Name=PRELID1; Synonyms=PRELI; ORFNames=CGI-106, SBBI12;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:1902511; P:negative regulation of apoptotic DNA fragmentation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010917; P:negative regulation of mitochondrial membrane potential; IDA:UniProtKB.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:0015914; P:phospholipid transport; IMP:GOC.
DR   GO; GO:1901857; P:positive regulation of cellular respiration; IDA:UniProtKB.
DR   GO; GO:0010950; P:positive regulation of endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:2001140; P:positive regulation of phospholipid transport; IDA:UniProtKB.
DR   GO; GO:0070234; P:positive regulation of T cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0097035; P:regulation of membrane lipid distribution; IDA:UniProtKB.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IDA:UniProtKB.
DR   GO; GO:0045580; P:regulation of T cell differentiation; IDA:UniProtKB.
//
ID   PRLHR_HUMAN             Reviewed;         370 AA.
AC   P49683; O75194; Q502U8; Q5VXR9;
DE   RecName: Full=Prolactin-releasing peptide receptor;
DE            Short=PrRP receptor;
DE            Short=PrRPR;
DE   AltName: Full=G-protein coupled receptor 10;
DE   AltName: Full=hGR3;
GN   Name=PRLHR; Synonyms=GPR10, GR3;
DR   GuidetoPHARMACOLOGY; 337; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008188; F:neuropeptide receptor activity; TAS:ProtInc.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; TAS:GOC.
//
ID   PRLR_HUMAN              Reviewed;         622 AA.
AC   P16471; B2R882; D1MDP1; Q16354; Q8TD75; Q8TD78; Q96P35; Q96P36;
AC   Q9BX87; Q9UHJ5;
DE   RecName: Full=Prolactin receptor;
DE            Short=PRL-R;
DE   Flags: Precursor;
GN   Name=PRLR;
DR   GuidetoPHARMACOLOGY; 1721; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042978; F:ornithine decarboxylase activator activity; NAS:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IPI:BHF-UCL.
DR   GO; GO:0004925; F:prolactin receptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0042977; P:activation of JAK2 kinase activity; NAS:UniProtKB.
DR   GO; GO:0007171; P:activation of transmembrane receptor protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007566; P:embryo implantation; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0038161; P:prolactin signaling pathway; NAS:GOC.
DR   GO; GO:0006694; P:steroid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
//
ID   PRL_HUMAN               Reviewed;         227 AA.
AC   P01236; Q15199; Q92996;
DE   RecName: Full=Prolactin;
DE            Short=PRL;
DE   Flags: Precursor;
GN   Name=PRL;
DR   GO; GO:0005148; F:prolactin receptor binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; NAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:UniProtKB-KW.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:BHF-UCL.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEP:BHF-UCL.
//
ID   PRM2_HUMAN              Reviewed;         102 AA.
AC   P04554; Q6ZMM0;
DE   RecName: Full=Protamine-2;
DE   AltName: Full=Sperm histone P2;
DE   AltName: Full=Sperm protamine P2;
DE   Contains:
DE     RecName: Full=Basic nuclear protein HPI1;
DE   Contains:
DE     RecName: Full=Basic nuclear protein HPI2;
DE   Contains:
DE     RecName: Full=Basic nuclear protein HPS1;
DE   Contains:
DE     RecName: Full=Basic nuclear protein HPS2;
DE   Contains:
DE     RecName: Full=Sperm histone HP4;
DE     AltName: Full=Sperm protamine P4;
DE   Contains:
DE     RecName: Full=Sperm histone HP2;
DE     AltName: Full=Sperm protamine P2;
DE              Short=P2';
DE   Contains:
DE     RecName: Full=Sperm histone HP3;
DE     AltName: Full=P2'';
DE     AltName: Full=Sperm protamine P3;
GN   Name=PRM2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0006323; P:DNA packaging; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:InterPro.
//
ID   PRM3_HUMAN              Reviewed;         103 AA.
AC   Q9NNZ6;
DE   RecName: Full=Protamine-3;
DE   AltName: Full=Sperm protamine P3;
GN   Name=PRM3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   PRND_HUMAN              Reviewed;         176 AA.
AC   Q9UKY0; A7U7M5; Q9H311; Q9H312; Q9NTM4;
DE   RecName: Full=Prion-like protein doppel;
DE   AltName: Full=PrPLP;
DE   AltName: Full=Prion protein 2;
DE   Flags: Precursor;
GN   Name=PRND; Synonyms=DPL; ORFNames=UNQ1830/PRO3443;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   PRNT_HUMAN              Reviewed;          94 AA.
AC   Q86SH4; B2RPD9; B7ZBI9;
DE   RecName: Full=Putative testis-specific prion protein;
DE   AltName: Full=Protein M8;
DE   Flags: Precursor;
GN   Name=PRNT;
//
ID   PROB1_HUMAN             Reviewed;        1015 AA.
AC   E7EW31; B4E007;
DE   RecName: Full=Proline-rich basic protein 1;
GN   Name=PROB1; Synonyms=C5orf65;
//
ID   PROC_HUMAN              Reviewed;         461 AA.
AC   P04070; B4DPQ7; Q15189; Q15190; Q16001; Q53S74; Q9UC55;
DE   RecName: Full=Vitamin K-dependent protein C;
DE            EC=3.4.21.69;
DE   AltName: Full=Anticoagulant protein C;
DE   AltName: Full=Autoprothrombin IIA;
DE   AltName: Full=Blood coagulation factor XIV;
DE   Contains:
DE     RecName: Full=Vitamin K-dependent protein C light chain;
DE   Contains:
DE     RecName: Full=Vitamin K-dependent protein C heavy chain;
DE   Contains:
DE     RecName: Full=Activation peptide;
DE   Flags: Precursor;
GN   Name=PROC;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; TAS:UniProtKB.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   PROD2_HUMAN             Reviewed;         536 AA.
AC   Q9UF12;
DE   RecName: Full=Probable proline dehydrogenase 2;
DE            EC=1.5.5.2;
DE   AltName: Full=Kidney and liver proline oxidase 1;
DE            Short=HsPOX1;
DE   AltName: Full=Probable proline oxidase 2;
GN   Name=PRODH2;
DR   GO; GO:0004657; F:proline dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
DR   GO; GO:0010133; P:proline catabolic process to glutamate; IEA:UniProtKB-UniPathway.
//
ID   PROD_HUMAN              Reviewed;         600 AA.
AC   O43272; A6NF53; O14680; Q0P507; Q147W8; Q504W1; Q59FI8; Q6NV86;
AC   Q9UF13;
DE   RecName: Full=Proline dehydrogenase 1, mitochondrial;
DE            EC=1.5.5.2;
DE   AltName: Full=Proline oxidase;
DE   AltName: Full=Proline oxidase 2;
DE   AltName: Full=p53-induced gene 6 protein;
DE   Flags: Precursor;
GN   Name=PRODH; Synonyms=PIG6, POX2;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0071949; F:FAD binding; IDA:UniProtKB.
DR   GO; GO:0004657; F:proline dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0019470; P:4-hydroxyproline catabolic process; TAS:BHF-UCL.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006537; P:glutamate biosynthetic process; IEA:InterPro.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; NAS:UniProtKB.
DR   GO; GO:0006562; P:proline catabolic process; TAS:Reactome.
DR   GO; GO:0010133; P:proline catabolic process to glutamate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006560; P:proline metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PROF1_HUMAN             Reviewed;         140 AA.
AC   P07737; Q53Y44;
DE   RecName: Full=Profilin-1;
DE   AltName: Full=Epididymis tissue protein Li 184a;
DE   AltName: Full=Profilin I;
GN   Name=PFN1;
DR   GO; GO:0003779; F:actin binding; IPI:UniProtKB.
DR   GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IDA:UniProt.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0032232; P:negative regulation of actin filament bundle assembly; IMP:UniProt.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IDA:UniProt.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProt.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IGI:UniProt.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProt.
DR   GO; GO:0051054; P:positive regulation of DNA metabolic process; IEA:Ensembl.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProt.
DR   GO; GO:1900029; P:positive regulation of ruffle assembly; IMP:UniProt.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050434; P:positive regulation of viral transcription; IEA:Ensembl.
//
ID   PROF2_HUMAN             Reviewed;         140 AA.
AC   P35080; B2R4C8; D3DNI4; Q4VBQ4; Q8WVF9; Q9HBK2;
DE   RecName: Full=Profilin-2;
DE   AltName: Full=Profilin II;
GN   Name=PFN2;
DR   GO; GO:0003785; F:actin monomer binding; IPI:UniProt.
DR   GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IDA:UniProt.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IDA:UniProt.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IMP:UniProt.
DR   GO; GO:1900028; P:negative regulation of ruffle assembly; IMP:UniProt.
DR   GO; GO:0032233; P:positive regulation of actin filament bundle assembly; IMP:UniProt.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IGI:UniProt.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProt.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:UniProt.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProt.
DR   GO; GO:2000300; P:regulation of synaptic vesicle exocytosis; IEA:Ensembl.
//
ID   PROF3_HUMAN             Reviewed;         137 AA.
AC   P60673; A2RUL3;
DE   RecName: Full=Profilin-3;
DE   AltName: Full=Profilin III;
GN   Name=PFN3;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
//
ID   PROF4_HUMAN             Reviewed;         129 AA.
AC   Q8NHR9; Q53TL9;
DE   RecName: Full=Profilin-4;
DE   AltName: Full=Profilin IV;
GN   Name=PFN4;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
//
ID   PROK1_HUMAN             Reviewed;         105 AA.
AC   P58294; Q5VWD4; Q8TC69;
DE   RecName: Full=Prokineticin-1;
DE   AltName: Full=Endocrine-gland-derived vascular endothelial growth factor;
DE            Short=EG-VEGF;
DE   AltName: Full=Mambakine;
DE   Flags: Precursor;
GN   Name=PROK1; ORFNames=UNQ600/PRO1186;
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045765; P:regulation of angiogenesis; IEA:Ensembl.
//
ID   PROK2_HUMAN             Reviewed;         129 AA.
AC   Q9HC23; Q53Z79; Q6ISR0;
DE   RecName: Full=Prokineticin-2;
DE            Short=PK2;
DE   AltName: Full=Protein Bv8 homolog;
DE   Flags: Precursor;
GN   Name=PROK2; Synonyms=BV8;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; TAS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:UniProtKB.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IDA:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IMP:UniProtKB.
//
ID   PROL4_HUMAN             Reviewed;         134 AA.
AC   Q16378; A8KA69; F5H0D7; Q8NFB3;
DE   RecName: Full=Proline-rich protein 4;
DE   AltName: Full=Lacrimal proline-rich protein;
DE   AltName: Full=Nasopharyngeal carcinoma-associated proline-rich protein 4;
DE   Flags: Precursor;
GN   Name=PRR4; Synonyms=LPRP, PROL4;
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PROL1_HUMAN             Reviewed;         248 AA.
AC   Q99935; A8MZ07; P85047;
DE   RecName: Full=Proline-rich protein 1;
DE            Short=PRL1;
DE   AltName: Full=Basic proline-rich lacrimal protein;
DE   Contains:
DE     RecName: Full=Opiorphin;
DE   Flags: Precursor;
GN   Name=PROL1; Synonyms=BPLP;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0030414; F:peptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IDA:UniProtKB.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   PROM1_HUMAN             Reviewed;         865 AA.
AC   O43490; Q6SV49; Q6SV50; Q6SV51; Q6SV52; Q6SV53; Q96EN6;
DE   RecName: Full=Prominin-1;
DE   AltName: Full=Antigen AC133;
DE   AltName: Full=Prominin-like protein 1;
DE   AltName: CD_antigen=CD133;
DE   Flags: Precursor;
GN   Name=PROM1; Synonyms=PROML1; ORFNames=MSTP061;
DR   GO; GO:0042805; F:actinin binding; IDA:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0060219; P:camera-type eye photoreceptor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072139; P:glomerular parietal epithelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:BHF-UCL.
DR   GO; GO:2000768; P:positive regulation of nephron tubule epithelial cell differentiation; IMP:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IMP:BHF-UCL.
//
ID   PROM2_HUMAN             Reviewed;         834 AA.
AC   Q8N271; A8K2V1; Q2HIX6; Q8NB84; Q8TAE2;
DE   RecName: Full=Prominin-2;
DE            Short=PROM-2;
DE   AltName: Full=Prominin-like protein 2;
DE            Short=hPROML2;
DE   Flags: Precursor;
GN   Name=PROM2; Synonyms=PROML2; ORFNames=UNQ2521/PRO6014;
DR   GO; GO:0015485; F:cholesterol binding; ISS:UniProt.
DR   GO; GO:2001287; P:negative regulation of caveolin-mediated endocytosis; IDA:UniProt.
DR   GO; GO:0048550; P:negative regulation of pinocytosis; IDA:UniProt.
DR   GO; GO:0031346; P:positive regulation of cell projection organization; IDA:UniProt.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProt.
DR   GO; GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProt.
//
ID   PROP1_HUMAN             Reviewed;         226 AA.
AC   O75360;
DE   RecName: Full=Homeobox protein prophet of Pit-1;
DE            Short=PROP-1;
DE   AltName: Full=Pituitary-specific homeodomain factor;
GN   Name=PROP1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0048850; P:hypophysis morphogenesis; IEA:Ensembl.
DR   GO; GO:0021979; P:hypothalamus cell differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060126; P:somatotropin secreting cell differentiation; IEA:Ensembl.
//
ID   PROP_HUMAN              Reviewed;         469 AA.
AC   P27918; O15134; O15135; O15136; O75826;
DE   RecName: Full=Properdin;
DE   AltName: Full=Complement factor P;
DE   Flags: Precursor;
GN   Name=CFP; Synonyms=PFC;
DR   GO; GO:0006956; P:complement activation; TAS:Reactome.
DR   GO; GO:0006957; P:complement activation, alternative pathway; TAS:Reactome.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   PROSC_HUMAN             Reviewed;         275 AA.
AC   O94903; Q6FI94;
DE   RecName: Full=Proline synthase co-transcribed bacterial homolog protein;
GN   Name=PROSC;
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IBA:RefGenome.
//
ID   PROS_HUMAN              Reviewed;         676 AA.
AC   P07225; A8KAC9; D3DN28; Q15518; Q7Z715; Q9UCZ8;
DE   RecName: Full=Vitamin K-dependent protein S;
DE   Flags: Precursor;
GN   Name=PROS1; Synonyms=PROS;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0042730; P:fibrinolysis; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
//
ID   PROX2_HUMAN             Reviewed;         592 AA.
AC   Q3B8N5; C9J5W1; Q8N9Q3;
DE   RecName: Full=Prospero homeobox protein 2;
DE   AltName: Full=Homeobox prospero-like protein PROX2;
DE            Short=PROX-2;
GN   Name=PROX2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PROX1_HUMAN             Reviewed;         737 AA.
AC   Q92786; A6NK29; A8K2B1; Q5SW76; Q8TB91;
DE   RecName: Full=Prospero homeobox protein 1;
DE   AltName: Full=Homeobox prospero-like protein PROX1;
DE            Short=PROX-1;
GN   Name=PROX1;
DR   GO; GO:0050692; F:DBD domain binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IMP:BHF-UCL.
DR   GO; GO:0050693; F:LBD domain binding; IPI:BHF-UCL.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0060414; P:aorta smooth muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0055009; P:atrial cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007420; P:brain development; IEP:BHF-UCL.
DR   GO; GO:0001709; P:cell fate determination; IEA:Ensembl.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.
DR   GO; GO:0021516; P:dorsal spinal cord development; ISS:BHF-UCL.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; IEP:BHF-UCL.
DR   GO; GO:0060214; P:endocardium formation; ISS:BHF-UCL.
DR   GO; GO:0002194; P:hepatocyte cell migration; IEA:Ensembl.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEP:BHF-UCL.
DR   GO; GO:0072574; P:hepatocyte proliferation; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEP:BHF-UCL.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEP:BHF-UCL.
DR   GO; GO:0070309; P:lens fiber cell morphogenesis; IEP:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEP:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IEP:BHF-UCL.
DR   GO; GO:0001946; P:lymphangiogenesis; IDA:BHF-UCL.
DR   GO; GO:0060836; P:lymphatic endothelial cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0070858; P:negative regulation of bile acid biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0021915; P:neural tube development; ISS:BHF-UCL.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; ISS:BHF-UCL.
DR   GO; GO:0030910; P:olfactory placode formation; ISS:BHF-UCL.
DR   GO; GO:0046619; P:optic placode formation involved in camera-type eye formation; ISS:BHF-UCL.
DR   GO; GO:0043049; P:otic placode formation; ISS:BHF-UCL.
DR   GO; GO:0031016; P:pancreas development; IEP:BHF-UCL.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:BHF-UCL.
DR   GO; GO:1901978; P:positive regulation of cell cycle checkpoint; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000979; P:positive regulation of forebrain neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0060421; P:positive regulation of heart growth; ISS:BHF-UCL.
DR   GO; GO:2000179; P:positive regulation of neural precursor cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0060298; P:positive regulation of sarcomere organization; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0060849; P:regulation of transcription involved in lymphatic endothelial cell fate commitment; IMP:BHF-UCL.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0030240; P:skeletal muscle thin filament assembly; ISS:BHF-UCL.
DR   GO; GO:0048845; P:venous blood vessel morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0055005; P:ventricular cardiac myofibril assembly; ISS:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   PROZ_HUMAN              Reviewed;         400 AA.
AC   P22891; A6NMB4; Q15213; Q5JVF5; Q5JVF6;
DE   RecName: Full=Vitamin K-dependent protein Z;
DE   Flags: Precursor;
GN   Name=PROZ;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
//
ID   PRP16_HUMAN             Reviewed;        1227 AA.
AC   Q92620; D3DWS7; O75212; Q96HN7;
DE   RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase DHX38;
DE   AltName: Full=DEAH box protein 38;
GN   Name=DHX38; Synonyms=DDX38, KIAA0224, PRP16;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   PRP17_HUMAN             Reviewed;         579 AA.
AC   O60508; B2RBC5; O75471; Q5SRN0; Q9UPG1;
DE   RecName: Full=Pre-mRNA-processing factor 17;
DE   AltName: Full=Cell division cycle 40 homolog;
DE   AltName: Full=EH-binding protein 3;
DE            Short=Ehb3;
DE   AltName: Full=PRP17 homolog;
DE            Short=hPRP17;
GN   Name=CDC40; Synonyms=EHB3, PRP17, PRPF17;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   PRP18_HUMAN             Reviewed;         342 AA.
AC   Q99633; Q5T9P9; Q9BUI9;
DE   RecName: Full=Pre-mRNA-splicing factor 18;
DE   AltName: Full=PRP18 homolog;
DE            Short=hPRP18;
GN   Name=PRPF18; Synonyms=HPRP18;
DR   GO; GO:0019870; F:potassium channel inhibitor activity; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   PRP19_HUMAN             Reviewed;         504 AA.
AC   Q9UMS4;
DE   RecName: Full=Pre-mRNA-processing factor 19;
DE   AltName: Full=Nuclear matrix protein 200;
DE   AltName: Full=PRP19/PSO4 homolog;
DE            Short=hPso4;
DE   AltName: Full=Senescence evasion factor;
GN   Name=PRPF19; Synonyms=NMP200, PRP19, SNEV;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:MGI.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048711; P:positive regulation of astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:MGI.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IMP:BHF-UCL.
//
ID   PRP1_HUMAN              Reviewed;         392 AA.
AC   P04280; Q08805; Q15186; Q15187; Q15214; Q15215; Q16038;
DE   RecName: Full=Basic salivary proline-rich protein 1;
DE            Short=Salivary proline-rich protein;
DE   Contains:
DE     RecName: Full=Proline-rich peptide II-2;
DE   Contains:
DE     RecName: Full=Basic peptide IB-6;
DE   Contains:
DE     RecName: Full=Peptide P-H;
DE   Flags: Precursor;
GN   Name=PRB1;
//
ID   PRP31_HUMAN             Reviewed;         499 AA.
AC   Q8WWY3; Q17RB4; Q8N7F9; Q9H271; Q9Y439;
DE   RecName: Full=U4/U6 small nuclear ribonucleoprotein Prp31;
DE   AltName: Full=Pre-mRNA-processing factor 31;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-99;
DE   AltName: Full=U4/U6 snRNP 61 kDa protein;
DE            Short=Protein 61K;
DE            Short=hPrp31;
GN   Name=PRPF31; Synonyms=PRP31;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:MGI.
DR   GO; GO:0070990; F:snRNP binding; IPI:BHF-UCL.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:BHF-UCL.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IMP:BHF-UCL.
//
ID   PRP39_HUMAN             Reviewed;         669 AA.
AC   Q86UA1; Q08AL1; Q08AL2; Q9NUU5;
DE   RecName: Full=Pre-mRNA-processing factor 39;
DE   AltName: Full=PRP39 homolog;
GN   Name=PRPF39;
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PRP4B_HUMAN             Reviewed;        1007 AA.
AC   Q13523; A8K5C9; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6;
DE   RecName: Full=Serine/threonine-protein kinase PRP4 homolog;
DE            EC=2.7.11.1;
DE   AltName: Full=PRP4 kinase;
DE   AltName: Full=PRP4 pre-mRNA-processing factor 4 homolog;
GN   Name=PRPF4B; Synonyms=KIAA0536, PRP4, PRP4H, PRP4K;
DR   GuidetoPHARMACOLOGY; 2177; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   PRP4_HUMAN              Reviewed;         522 AA.
AC   O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4;
DE   RecName: Full=U4/U6 small nuclear ribonucleoprotein Prp4;
DE   AltName: Full=PRP4 homolog;
DE            Short=hPrp4;
DE   AltName: Full=U4/U6 snRNP 60 kDa protein;
DE   AltName: Full=WD splicing factor Prp4;
GN   Name=PRPF4; Synonyms=PRP4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:BHF-UCL.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; NAS:UniProtKB.
//
ID   PRP6_HUMAN              Reviewed;         941 AA.
AC   O94906; B2RAR5; B3KMC6; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8;
AC   Q9NTE6;
DE   RecName: Full=Pre-mRNA-processing factor 6;
DE   AltName: Full=Androgen receptor N-terminal domain-transactivating protein 1;
DE            Short=ANT-1;
DE   AltName: Full=PRP6 homolog;
DE   AltName: Full=U5 snRNP-associated 102 kDa protein;
DE            Short=U5-102 kDa protein;
GN   Name=PRPF6; Synonyms=C20orf14;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; IDA:MGI.
DR   GO; GO:0003713; F:transcription coactivator activity; IGI:MGI.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006403; P:RNA localization; IMP:MGI.
DR   GO; GO:0008380; P:RNA splicing; NAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; NAS:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; NAS:UniProtKB.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IMP:BHF-UCL.
//
ID   PRP8_HUMAN              Reviewed;        2335 AA.
AC   Q6P2Q9; O14547; O75965;
DE   RecName: Full=Pre-mRNA-processing-splicing factor 8;
DE   AltName: Full=220 kDa U5 snRNP-specific protein;
DE   AltName: Full=PRP8 homolog;
DE   AltName: Full=Splicing factor Prp8;
DE   AltName: Full=p220;
GN   Name=PRPF8; Synonyms=PRPC8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030623; F:U5 snRNA binding; IEA:InterPro.
DR   GO; GO:0017070; F:U6 snRNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   PRPC_HUMAN              Reviewed;         166 AA.
AC   P02810; A2VCM0; A3KN66; A5D902; B2RMW2; Q4VBP2; Q53XA2; Q6P2F6;
DE   RecName: Full=Salivary acidic proline-rich phosphoprotein 1/2;
DE   AltName: Full=Db-s;
DE   AltName: Full=PRP-1/PRP-2;
DE   AltName: Full=Parotid acidic protein;
DE            Short=Pa;
DE   AltName: Full=Parotid double-band protein;
DE   AltName: Full=Parotid isoelectric focusing variant protein;
DE            Short=PIF-S;
DE   AltName: Full=Parotid proline-rich protein 1/2;
DE   AltName: Full=Pr1/Pr2;
DE   AltName: Full=Protein C;
DE   Contains:
DE     RecName: Full=Salivary acidic proline-rich phosphoprotein 1/2;
DE   Contains:
DE     RecName: Full=Salivary acidic proline-rich phosphoprotein 3/4;
DE     AltName: Full=Db-F;
DE     AltName: Full=PIF-F;
DE     AltName: Full=PRP-3/PRP-4;
DE     AltName: Full=Protein A;
DE   Contains:
DE     RecName: Full=Peptide P-C;
DE   Flags: Precursor;
GN   Name=PRH1;
GN   and
GN   Name=PRH2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PRPF3_HUMAN             Reviewed;         683 AA.
AC   O43395; O43446; Q5VT54;
DE   RecName: Full=U4/U6 small nuclear ribonucleoprotein Prp3;
DE   AltName: Full=Pre-mRNA-splicing factor 3;
DE            Short=hPrp3;
DE   AltName: Full=U4/U6 snRNP 90 kDa protein;
GN   Name=PRPF3; Synonyms=HPRP3, PRP3;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; NAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   PRPH2_HUMAN             Reviewed;         346 AA.
AC   P23942; Q5TFH5; Q6DK65;
DE   RecName: Full=Peripherin-2;
DE   AltName: Full=Retinal degeneration slow protein;
DE   AltName: Full=Tetraspanin-22;
DE            Short=Tspan-22;
GN   Name=PRPH2; Synonyms=PRPH, RDS, TSPAN22;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   PRPK_HUMAN              Reviewed;         253 AA.
AC   Q96S44; B3KU44; Q3T977; Q5JZ01; Q6NZ60; Q96FM7; Q9NQE6;
DE   RecName: Full=TP53-regulating kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Atypical serine/threonine protein kinase TP53RK;
DE   AltName: Full=EKC/KEOPS complex subunit TP53RK;
DE            EC=3.6.-.-;
DE   AltName: Full=Nori-2;
DE   AltName: Full=p53-related protein kinase;
GN   Name=TP53RK; Synonyms=C20orf64, PRPK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0002039; F:p53 binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   PRPS1_HUMAN             Reviewed;         318 AA.
AC   P60891; B1ALA8; B2R6T7; D3DUX6; P09329;
DE   RecName: Full=Ribose-phosphate pyrophosphokinase 1;
DE            EC=2.7.6.1;
DE   AltName: Full=PPRibP;
DE   AltName: Full=Phosphoribosyl pyrophosphate synthase I;
DE            Short=PRS-I;
GN   Name=PRPS1;
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0016208; F:AMP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; IDA:UniProtKB.
DR   GO; GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0006167; P:AMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0046101; P:hypoxanthine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IMP:UniProtKB.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0034418; P:urate biosynthetic process; IMP:UniProtKB.
//
ID   PRPS2_HUMAN             Reviewed;         318 AA.
AC   P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7;
DE   RecName: Full=Ribose-phosphate pyrophosphokinase 2;
DE            EC=2.7.6.1;
DE   AltName: Full=PPRibP;
DE   AltName: Full=Phosphoribosyl pyrophosphate synthase II;
DE            Short=PRS-II;
GN   Name=PRPS2;
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0016208; F:AMP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
DR   GO; GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006167; P:AMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
//
ID   PRPS3_HUMAN             Reviewed;         318 AA.
AC   P21108; Q6P5P6;
DE   RecName: Full=Ribose-phosphate pyrophosphokinase 3;
DE            EC=2.7.6.1;
DE   AltName: Full=Phosphoribosyl pyrophosphate synthase 1-like 1;
DE            Short=PRPS1-like 1;
DE   AltName: Full=Phosphoribosyl pyrophosphate synthase III;
DE            Short=PRS-III;
GN   Name=PRPS1L1; Synonyms=PRPS3, PRPSL;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
DR   GO; GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
//
ID   PRR11_HUMAN             Reviewed;         360 AA.
AC   Q96HE9; Q9NUZ7; Q9NXE9;
DE   RecName: Full=Proline-rich protein 11;
GN   Name=PRR11;
//
ID   PRR12_HUMAN             Reviewed;        1215 AA.
AC   Q9ULL5; E9PB06; Q8N4J6;
DE   RecName: Full=Proline-rich protein 12;
GN   Name=PRR12; Synonyms=KIAA1205;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
//
ID   PRR13_HUMAN             Reviewed;         148 AA.
AC   Q9NZ81; Q0V8U0; Q6FIG7; Q6MZP8; Q6NXQ6; Q6PKF9;
DE   RecName: Full=Proline-rich protein 13;
DE   AltName: Full=Taxane-resistance protein;
GN   Name=PRR13; Synonyms=TXR1; ORFNames=BM-041;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PRR14_HUMAN             Reviewed;         585 AA.
AC   Q9BWN1; Q8WTX2;
DE   RecName: Full=Proline-rich protein 14;
GN   Name=PRR14;
//
ID   PRR15_HUMAN             Reviewed;         129 AA.
AC   Q8IV56;
DE   RecName: Full=Proline-rich protein 15;
GN   Name=PRR15;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   PRR16_HUMAN             Reviewed;         304 AA.
AC   Q569H4; D3DSZ0; Q8IXY1; Q9NYI5;
DE   RecName: Full=Proline-rich protein 16;
DE   AltName: Full=Mesenchymal stem cell protein DSC54;
GN   Name=PRR16;
//
ID   PRR18_HUMAN             Reviewed;         295 AA.
AC   Q8N4B5;
DE   RecName: Full=Proline-rich protein 18;
GN   Name=PRR18;
//
ID   PRR17_HUMAN             Reviewed;         217 AA.
AC   Q6ZNR8;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00176;
DE   AltName: Full=Putative proline-rich protein 17;
GN   Name=LINC00176; Synonyms=NCRNA00176, PRR17;
//
ID   PRR19_HUMAN             Reviewed;         356 AA.
AC   A6NJB7; A8K663; B3KW48; Q6P584;
DE   RecName: Full=Proline-rich protein 19;
GN   Name=PRR19;
//
ID   PRR22_HUMAN             Reviewed;         422 AA.
AC   Q8IZ63; E9PB31;
DE   RecName: Full=Proline-rich protein 22;
GN   Name=PRR22;
//
ID   PRR24_HUMAN             Reviewed;         142 AA.
AC   C9JVW0;
DE   RecName: Full=Proline-rich protein 24;
GN   Name=PRR24;
//
ID   PRR26_HUMAN             Reviewed;         221 AA.
AC   Q8N8Z3;
DE   RecName: Full=Proline-rich protein 26;
GN   Name=PRR26; Synonyms=C10orf108;
//
ID   PRR21_HUMAN             Reviewed;         389 AA.
AC   Q8WXC7;
DE   RecName: Full=Putative proline-rich protein 21;
GN   Name=PRR21;
//
ID   PRR29_HUMAN             Reviewed;         189 AA.
AC   P0C7W0; B3KMP0; B4DZJ9; B4E2F8; E9PGL5; J3QKX4;
DE   RecName: Full=Proline-rich protein 29;
GN   Name=PRR29; Synonyms=C17orf72;
//
ID   PRR25_HUMAN             Reviewed;         402 AA.
AC   Q96S07;
DE   RecName: Full=Proline-rich protein 25;
GN   Name=PRR25; ORFNames=gs64;
//
ID   PRR30_HUMAN             Reviewed;         412 AA.
AC   Q53SZ7; Q86UE2;
DE   RecName: Full=Proline-rich protein 30;
GN   Name=PRR30; Synonyms=C2orf53;
//
ID   PRR32_HUMAN             Reviewed;         298 AA.
AC   B1ATL7;
DE   RecName: Full=Proline-rich protein 32;
GN   Name=PRR32; Synonyms=CXorf64;
//
ID   PRR27_HUMAN             Reviewed;         219 AA.
AC   Q6MZM9; A8MXP0; Q6MZR6;
DE   RecName: Full=Proline-rich protein 27;
DE   Flags: Precursor;
GN   Name=PRR27; Synonyms=C4orf40;
//
ID   PRR35_HUMAN             Reviewed;         571 AA.
AC   P0CG20; B8ZZ27; Q8N233; Q96AX3; Q96S23;
DE   RecName: Full=Proline-rich protein 35;
DE   AltName: Full=Uncharacterized protein RJD1;
GN   Name=PRR35; Synonyms=C16orf11;
//
ID   PRR34_HUMAN             Reviewed;         138 AA.
AC   Q9NV39; B0QZ24;
DE   RecName: Full=Proline-rich protein 34;
GN   Name=PRR34; Synonyms=C22orf26;
//
ID   PRR3_HUMAN              Reviewed;         188 AA.
AC   P79522; A1A4H4; Q5RJB5; Q5STN6;
DE   RecName: Full=Proline-rich protein 3;
DE   AltName: Full=MHC class I region proline-rich protein CAT56;
GN   Name=PRR3; Synonyms=CAT56;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   PRR33_HUMAN             Reviewed;         331 AA.
AC   A8MZF0; A6NI49;
DE   RecName: Full=Proline-rich protein 33;
GN   Name=PRR33; Synonyms=C11orf89;
//
ID   PRR31_HUMAN             Reviewed;         230 AA.
AC   Q5SQ13;
DE   RecName: Full=Proline-rich protein 31;
GN   Name=PRR31; Synonyms=C9orf141;
//
ID   PRR5_HUMAN              Reviewed;         388 AA.
AC   P85299; B1AHF6; B1AHG5; B3KP73; O75983; O95695; Q5BIW2; Q5EAJ8;
AC   Q5EAJ9; Q5XKJ6; Q96RW1; Q96RW2; Q9HA49; Q9HC46; Q9NSG0; Q9NVX8;
AC   Q9NXL1; Q9UH20;
DE   RecName: Full=Proline-rich protein 5;
DE   AltName: Full=Protein observed with Rictor-1;
DE            Short=Protor-1;
GN   Name=PRR5; Synonyms=PROTOR1; ORFNames=PP610;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
//
ID   PRR5L_HUMAN             Reviewed;         368 AA.
AC   Q6MZQ0; A4QN22; E9PKY1; Q96H46; Q9H7V4;
DE   RecName: Full=Proline-rich protein 5-like;
DE   AltName: Full=Protein observed with Rictor-2;
DE            Short=Protor-2;
GN   Name=PRR5L; Synonyms=PROTOR2;
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0010762; P:regulation of fibroblast migration; IMP:UniProtKB.
DR   GO; GO:0038203; P:TORC2 signaling; IDA:UniProtKB.
//
ID   PRR7_HUMAN              Reviewed;         274 AA.
AC   Q8TB68; Q8WU53; Q9BTA7;
DE   RecName: Full=Proline-rich protein 7;
DE   AltName: Full=Synaptic proline-rich membrane protein;
GN   Name=PRR7;
//
ID   PRR9_HUMAN              Reviewed;         116 AA.
AC   Q5T870;
DE   RecName: Full=Proline-rich protein 9;
GN   Name=PRR9;
//
ID   PRRC1_HUMAN             Reviewed;         445 AA.
AC   Q96M27; Q69YM8; Q7L2U7; Q86Y42; Q8IVJ4; Q8IVL4; Q8NEZ7; Q96AJ3;
DE   RecName: Full=Protein PRRC1;
DE   AltName: Full=Proline-rich and coiled-coil-containing protein 1;
GN   Name=PRRC1;
//
ID   PRRP_HUMAN              Reviewed;          87 AA.
AC   P81277;
DE   RecName: Full=Prolactin-releasing peptide;
DE            Short=PrRP;
DE   AltName: Full=Prolactin-releasing hormone;
DE   Contains:
DE     RecName: Full=Prolactin-releasing peptide PrRP31;
DE   Contains:
DE     RecName: Full=Prolactin-releasing peptide PrRP20;
DE   Flags: Precursor;
GN   Name=PRLH; Synonyms=PRH;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0048483; P:autonomic nervous system development; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0002023; P:reduction of food intake in response to dietary excess; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
//
ID   PRRT1_HUMAN             Reviewed;         306 AA.
AC   Q99946; A6ND08; A6ND40; B0S869; Q5SSW4; Q5SSX7; Q5STI1; Q96DW3;
AC   Q96NQ8;
DE   RecName: Full=Proline-rich transmembrane protein 1;
DE   AltName: Full=Dispanin subfamily D member 1;
DE            Short=DSPD1;
GN   Name=PRRT1; Synonyms=C6orf31, NG5;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   PRRT2_HUMAN             Reviewed;         340 AA.
AC   Q7Z6L0; A8K8M8; Q8N2N8; Q8NAQ7; Q8ND36; Q96FA8;
DE   RecName: Full=Proline-rich transmembrane protein 2;
DE   AltName: Full=Dispanin subfamily B member 3;
DE            Short=DSPB3;
GN   Name=PRRT2;
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IMP:MGI.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   PRRT3_HUMAN             Reviewed;         981 AA.
AC   Q5FWE3; Q49AD0; Q6UXY6; Q8NBC9;
DE   RecName: Full=Proline-rich transmembrane protein 3;
DE   Flags: Precursor;
GN   Name=PRRT3; ORFNames=UNQ5823/PRO19642;
//
ID   PRRT4_HUMAN             Reviewed;         899 AA.
AC   C9JH25; A4D0Z9; C9JVW7;
DE   RecName: Full=Proline-rich transmembrane protein 4;
DE   Flags: Precursor;
GN   Name=PRRT4;
//
ID   PRRX1_HUMAN             Reviewed;         245 AA.
AC   P54821; B5BUM7; O60807;
DE   RecName: Full=Paired mesoderm homeobox protein 1;
DE   AltName: Full=Homeobox protein PHOX1;
DE   AltName: Full=Paired-related homeobox protein 1;
DE            Short=PRX-1;
GN   Name=PRRX1; Synonyms=PMX1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
//
ID   PRRX2_HUMAN             Reviewed;         253 AA.
AC   Q99811; Q5SZB5; Q9UIB3;
DE   RecName: Full=Paired mesoderm homeobox protein 2;
DE   AltName: Full=Paired-related homeobox protein 2;
DE            Short=PRX-2;
GN   Name=PRRX2; Synonyms=PMX2, PRX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   PRS23_HUMAN             Reviewed;         383 AA.
AC   O95084; B2RDJ1; Q6IBI0;
DE   RecName: Full=Serine protease 23;
DE            EC=3.4.21.-;
DE   AltName: Full=Putative secreted protein Zsig13;
DE   Flags: Precursor;
GN   Name=PRSS23; Synonyms=ZSIG13; ORFNames=UNQ270/PRO307;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS27_HUMAN             Reviewed;         290 AA.
AC   Q9BQR3;
DE   RecName: Full=Serine protease 27;
DE            EC=3.4.21.-;
DE   AltName: Full=Marapsin;
DE   AltName: Full=Pancreasin;
DE   Flags: Precursor;
GN   Name=PRSS27; Synonyms=MPN; ORFNames=UNQ1884/PRO4327;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS10_HUMAN             Reviewed;         389 AA.
AC   P62333; B2R975; P49719; Q6IBU3; Q92524;
DE   RecName: Full=26S protease regulatory subunit 10B;
DE   AltName: Full=26S proteasome AAA-ATPase subunit RPT4;
DE   AltName: Full=Proteasome 26S subunit ATPase 6;
DE   AltName: Full=Proteasome subunit p42;
GN   Name=PSMC6; Synonyms=SUG2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PRS29_HUMAN             Reviewed;         313 AA.
AC   A6NIE9;
DE   RecName: Full=Putative serine protease 29;
DE            EC=3.4.21.-;
DE   AltName: Full=Implantation serine proteinase 2-like protein;
DE            Short=ISP2-like protein;
DE   Flags: Precursor;
GN   Name=PRSS29P; Synonyms=ISP2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS33_HUMAN             Reviewed;         280 AA.
AC   Q8NF86; A6NNQ3; Q8N171;
DE   RecName: Full=Serine protease 33;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease EOS;
DE   Flags: Precursor;
GN   Name=PRSS33;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS35_HUMAN             Reviewed;         413 AA.
AC   Q8N3Z0; A8K7B3; Q9BQP6;
DE   RecName: Full=Inactive serine protease 35;
DE   Flags: Precursor;
GN   Name=PRSS35; Synonyms=C6orf158; ORFNames=UNQ522/PRO1057;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
//
ID   PRS37_HUMAN             Reviewed;         235 AA.
AC   A4D1T9; B2RPB5;
DE   RecName: Full=Probable inactive serine protease 37;
DE   AltName: Full=Probable inactive trypsin-X2;
DE   Flags: Precursor;
GN   Name=PRSS37; Synonyms=TRYX2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS38_HUMAN             Reviewed;         326 AA.
AC   A1L453; Q7RTY6;
DE   RecName: Full=Serine protease 38;
DE            EC=3.4.21.-;
DE   AltName: Full=Marapsin-2;
DE   Flags: Precursor;
GN   Name=PRSS38; Synonyms=MPN2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS41_HUMAN             Reviewed;         318 AA.
AC   Q7RTY9;
DE   RecName: Full=Putative serine protease 41;
DE            EC=3.4.21.-;
DE   AltName: Full=Testis serine protease 1;
DE            Short=TESSP-1;
DE   Flags: Precursor;
GN   Name=PRSS41; Synonyms=TESSP1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS42_HUMAN             Reviewed;         293 AA.
AC   Q7Z5A4;
DE   RecName: Full=Serine protease 42;
DE            EC=3.4.21.-;
DE   AltName: Full=Testis serine protease 2;
DE   Flags: Precursor;
GN   Name=PRSS42; Synonyms=TESSP2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS44_HUMAN             Reviewed;         344 AA.
AC   E7EML9;
DE   RecName: Full=Serine protease 44;
DE            EC=3.4.21.-;
DE   AltName: Full=Testis serine protease 4;
DE            Short=TESSP-4;
DE   Flags: Precursor;
GN   Name=PRSS44; Synonyms=TESSP4;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS45_HUMAN             Reviewed;         260 AA.
AC   Q7RTY3; A3KN77;
DE   RecName: Full=Serine protease 45;
DE            EC=3.4.21.-;
DE   AltName: Full=Testis serine protease 5;
GN   Name=PRSS45; Synonyms=TESSP5;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS46_HUMAN             Reviewed;         174 AA.
AC   E5RG02;
DE   RecName: Full=Putative serine protease 46;
DE            EC=3.4.21.-;
GN   Name=PRSS46;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS47_HUMAN             Reviewed;         375 AA.
AC   A8MTI9;
DE   RecName: Full=Putative serine protease 47;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=PRSS47;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS48_HUMAN             Reviewed;         328 AA.
AC   Q7RTY5; Q08E82; Q0VAD4;
DE   RecName: Full=Serine protease 48;
DE            EC=3.4.21.-;
DE   AltName: Full=Epidermis-specific serine protease-like protein;
DE   Flags: Precursor;
GN   Name=PRSS48; Synonyms=ESSPL;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS53_HUMAN             Reviewed;         553 AA.
AC   Q2L4Q9;
DE   RecName: Full=Serine protease 53;
DE            EC=3.4.21.-;
DE   AltName: Full=Polyserine protease 3;
DE            Short=Polyserase-3;
DE   Flags: Precursor;
GN   Name=PRSS53;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS54_HUMAN             Reviewed;         395 AA.
AC   Q6PEW0; Q96LN9; Q9NT77;
DE   RecName: Full=Inactive serine protease 54;
DE   AltName: Full=Cancer/testis antigen 67;
DE            Short=CT67;
DE   AltName: Full=Plasma kallikrein-like protein 4;
DE   Flags: Precursor;
GN   Name=PRSS54; Synonyms=KLKBL4;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS55_HUMAN             Reviewed;         352 AA.
AC   Q6UWB4; E5RJX5;
DE   RecName: Full=Serine protease 55;
DE            EC=3.4.21.-;
DE   AltName: Full=Testis serine protease 1;
DE            Short=T-SP1;
DE   Flags: Precursor;
GN   Name=PRSS55; Synonyms=TSP1; ORFNames=UNQ9391/PRO34284;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS4_HUMAN              Reviewed;         440 AA.
AC   P62191; P49014; Q03527; Q6IAW0; Q6NW36; Q96AZ3;
DE   RecName: Full=26S protease regulatory subunit 4;
DE            Short=P26s4;
DE   AltName: Full=26S proteasome AAA-ATPase subunit RPT2;
DE   AltName: Full=Proteasome 26S subunit ATPase 1;
GN   Name=PSMC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PRS56_HUMAN             Reviewed;         603 AA.
AC   P0CW18;
DE   RecName: Full=Serine protease 56;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=PRSS56;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; ISS:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
//
ID   PRS57_HUMAN             Reviewed;         283 AA.
AC   Q6UWY2; B2RNW8;
DE   RecName: Full=Serine protease 57;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease 1-like protein 1;
DE   Flags: Precursor;
GN   Name=PRSS57; Synonyms=PRSSL1; ORFNames=UNQ782/PRO1599;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS58_HUMAN             Reviewed;         241 AA.
AC   Q8IYP2; B3KVJ6; D3DXD2;
DE   RecName: Full=Serine protease 58;
DE            EC=3.4.21.4;
DE   AltName: Full=Trypsin-X3;
DE   Flags: Precursor;
GN   Name=PRSS58; Synonyms=TRY1, TRYX3; ORFNames=UNQ2540/PRO6090;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   PRS6A_HUMAN             Reviewed;         439 AA.
AC   P17980; B2R8V1; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3;
DE   RecName: Full=26S protease regulatory subunit 6A;
DE   AltName: Full=26S proteasome AAA-ATPase subunit RPT5;
DE   AltName: Full=Proteasome 26S subunit ATPase 3;
DE   AltName: Full=Proteasome subunit P50;
DE   AltName: Full=Tat-binding protein 1;
DE            Short=TBP-1;
GN   Name=PSMC3; Synonyms=TBP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; ISS:GOC.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PRS6B_HUMAN             Reviewed;         418 AA.
AC   P43686; Q96FV5; Q9UBM3; Q9UEX3;
DE   RecName: Full=26S protease regulatory subunit 6B;
DE   AltName: Full=26S proteasome AAA-ATPase subunit RPT3;
DE   AltName: Full=MB67-interacting protein;
DE   AltName: Full=MIP224;
DE   AltName: Full=Proteasome 26S subunit ATPase 4;
DE   AltName: Full=Tat-binding protein 7;
DE            Short=TBP-7;
GN   Name=PSMC4; Synonyms=MIP224, TBP7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PRS7_HUMAN              Reviewed;         433 AA.
AC   P35998; A4D0Q1; Q3LIA5; Q9UDI3;
DE   RecName: Full=26S protease regulatory subunit 7;
DE   AltName: Full=26S proteasome AAA-ATPase subunit RPT1;
DE   AltName: Full=Proteasome 26S subunit ATPase 2;
DE   AltName: Full=Protein MSS1;
GN   Name=PSMC2; Synonyms=MSS1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PRS8_HUMAN              Reviewed;         406 AA.
AC   P62195; A8K3Z3; A8K763; O35051; O43208; P47210; P52915; P52916;
DE   RecName: Full=26S protease regulatory subunit 8;
DE   AltName: Full=26S proteasome AAA-ATPase subunit RPT6;
DE   AltName: Full=Proteasome 26S subunit ATPase 5;
DE   AltName: Full=Proteasome subunit p45;
DE   AltName: Full=Thyroid hormone receptor-interacting protein 1;
DE            Short=TRIP1;
DE   AltName: Full=p45/SUG;
GN   Name=PSMC5; Synonyms=SUG1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031531; F:thyrotropin-releasing hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0090261; P:positive regulation of inclusion body assembly; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PRSR1_HUMAN             Reviewed;         944 AA.
AC   Q86XN7; Q6P2S2; Q7Z3X5; Q8N3D2; Q8N3P1; Q9H9M1;
DE   RecName: Full=Proline and serine-rich protein 1;
GN   Name=PROSER1; Synonyms=C13orf23, KIAA2032;
//
ID   PRSR2_HUMAN             Reviewed;         435 AA.
AC   Q86WR7; D3DRR8; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q8N317;
DE   RecName: Full=Proline and serine-rich protein 2;
GN   Name=PROSER2; Synonyms=C10orf47;
//
ID   PRSS8_HUMAN             Reviewed;         343 AA.
AC   Q16651; Q9UCA3;
DE   RecName: Full=Prostasin;
DE            EC=3.4.21.-;
DE   AltName: Full=Channel-activating protease 1;
DE            Short=CAP1;
DE   AltName: Full=Serine protease 8;
DE   Contains:
DE     RecName: Full=Prostasin light chain;
DE   Contains:
DE     RecName: Full=Prostasin heavy chain;
DE   Flags: Precursor;
GN   Name=PRSS8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
//
ID   PRTG_HUMAN              Reviewed;        1150 AA.
AC   Q2VWP7; Q8N7D8;
DE   RecName: Full=Protogenin;
DE   AltName: Full=Protein Shen-Dan;
DE   Flags: Precursor;
GN   Name=PRTG;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   PRTN3_HUMAN             Reviewed;         256 AA.
AC   P24158; P15637; P18078; Q4VB08; Q4VB09; Q6LBM7; Q6LBN2; Q9UD25;
AC   Q9UQD8;
DE   RecName: Full=Myeloblastin;
DE            EC=3.4.21.76;
DE   AltName: Full=AGP7;
DE   AltName: Full=C-ANCA antigen;
DE   AltName: Full=Leukocyte proteinase 3;
DE            Short=PR-3;
DE            Short=PR3;
DE   AltName: Full=Neutrophil proteinase 4;
DE            Short=NP-4;
DE   AltName: Full=P29;
DE   AltName: Full=Wegener autoantigen;
DE   Flags: Precursor;
GN   Name=PRTN3; Synonyms=MBN;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0030574; P:collagen catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0097029; P:mature dendritic cell differentiation; IDA:UniProtKB.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   PRUN2_HUMAN             Reviewed;        3088 AA.
AC   Q8WUY3; B3KYC4; B4DQH8; O15073; Q58A63; Q5JUB6; Q5T304; Q5T476;
AC   Q6T2V6; Q6T2V7; Q8N665;
DE   RecName: Full=Protein prune homolog 2;
DE   AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1;
GN   Name=PRUNE2; Synonyms=BMCC1, BNIPXL, C9orf65, KIAA0367;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016462; F:pyrophosphatase activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
//
ID   PRUNE_HUMAN             Reviewed;         453 AA.
AC   Q86TP1; B2RCH8; B4DFL7; Q5SZF9; Q659E5; Q6P4E0; Q8N654; Q96JU5;
AC   Q9C071; Q9C072; Q9UIV0;
DE   RecName: Full=Protein prune homolog;
DE            Short=hPrune;
DE            EC=3.6.1.1;
DE   AltName: Full=Drosophila-related expressed sequence 17;
DE            Short=DRES-17;
DE            Short=DRES17;
DE   AltName: Full=HTcD37;
GN   Name=PRUNE;
DR   GO; GO:0004427; F:inorganic diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PRVA_HUMAN              Reviewed;         110 AA.
AC   P20472; B2R4H7; P78378; Q4VB78; Q5R3Q9;
DE   RecName: Full=Parvalbumin alpha;
GN   Name=PVALB;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Ensembl.
//
ID   PRXD1_HUMAN             Reviewed;         169 AA.
AC   A6NEY8;
DE   RecName: Full=Putative prolyl-tRNA synthetase associated domain-containing protein 1;
DE   AltName: Full=PrdX deacylase domain-containing protein 1;
DE   AltName: Full=Prolyl-tRNA synthetase associated domain-containing protein 1 pseudogene;
GN   Name=PRORSD1P; Synonyms=NCRNA00117, PRDXDD1P;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
//
ID   PRY_HUMAN               Reviewed;         147 AA.
AC   O14603; B7ZLM1; Q14D09;
DE   RecName: Full=PTPN13-like protein, Y-linked;
DE   AltName: Full=Testis-specific PTP-BL-related Y protein;
GN   Name=PRY; Synonyms=PRY1, PTPN13LY;
GN   and
GN   Name=PRY2; Synonyms=PTPN13LY2;
GN   and
GN   Name=PRYP3;
GN   and
GN   Name=PRYP4;
//
ID   PS1C1_HUMAN             Reviewed;         152 AA.
AC   Q9UIG5; B0V083; Q5ST21; Q86WJ8; Q86WJ9; Q96QC3;
DE   RecName: Full=Psoriasis susceptibility 1 candidate gene 1 protein;
DE   AltName: Full=Protein SEEK1;
GN   Name=PSORS1C1; Synonyms=C6orf16, SEEK1;
//
ID   PS1C2_HUMAN             Reviewed;         136 AA.
AC   Q9UIG4; Q5STD0;
DE   RecName: Full=Psoriasis susceptibility 1 candidate gene 2 protein;
DE   AltName: Full=Protein SPR1;
DE   Flags: Precursor;
GN   Name=PSORS1C2; Synonyms=C6orf17, SPR1;
//
ID   PSA1_HUMAN              Reviewed;         263 AA.
AC   P25786; A8K400; Q53YE8; Q9BRV9;
DE   RecName: Full=Proteasome subunit alpha type-1;
DE            EC=3.4.25.1;
DE   AltName: Full=30 kDa prosomal protein;
DE            Short=PROS-30;
DE   AltName: Full=Macropain subunit C2;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C2;
DE   AltName: Full=Proteasome component C2;
DE   AltName: Full=Proteasome nu chain;
GN   Name=PSMA1; Synonyms=HC2, NU, PROS30, PSC2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA2_HUMAN              Reviewed;         234 AA.
AC   P25787; Q6ICS6; Q9BU45;
DE   RecName: Full=Proteasome subunit alpha type-2;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain subunit C3;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C3;
DE   AltName: Full=Proteasome component C3;
GN   Name=PSMA2; Synonyms=HC3, PSC3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA3_HUMAN              Reviewed;         255 AA.
AC   P25788; B2RCK6; Q86U83; Q8N1D8; Q9BS70;
DE   RecName: Full=Proteasome subunit alpha type-3;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain subunit C8;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C8;
DE   AltName: Full=Proteasome component C8;
GN   Name=PSMA3; Synonyms=HC8, PSC8;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA4_HUMAN              Reviewed;         261 AA.
AC   P25789; D3DW86; Q53XP2; Q567Q5; Q8TBD1;
DE   RecName: Full=Proteasome subunit alpha type-4;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain subunit C9;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C9;
DE   AltName: Full=Proteasome component C9;
DE   AltName: Full=Proteasome subunit L;
GN   Name=PSMA4; Synonyms=HC9, PSC9;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA5_HUMAN              Reviewed;         241 AA.
AC   P28066; B2R8F6; B4E2V4; Q3T1C1; Q6IBF7;
DE   RecName: Full=Proteasome subunit alpha type-5;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain zeta chain;
DE   AltName: Full=Multicatalytic endopeptidase complex zeta chain;
DE   AltName: Full=Proteasome zeta chain;
GN   Name=PSMA5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA6_HUMAN              Reviewed;         246 AA.
AC   P60900; B2R7J9; B4DQR4; B4DXJ9; P34062; Q6IB60;
DE   RecName: Full=Proteasome subunit alpha type-6;
DE            EC=3.4.25.1;
DE   AltName: Full=27 kDa prosomal protein;
DE            Short=PROS-27;
DE            Short=p27K;
DE   AltName: Full=Macropain iota chain;
DE   AltName: Full=Multicatalytic endopeptidase complex iota chain;
DE   AltName: Full=Proteasome iota chain;
GN   Name=PSMA6; Synonyms=PROS27;
DR   GO; GO:0004175; F:endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035639; F:purine ribonucleoside triphosphate binding; NAS:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0051603; P:proteolysis involved in cellular protein catabolic process; IEA:InterPro.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA7L_HUMAN             Reviewed;         256 AA.
AC   Q8TAA3; B0YJ75; Q8IVP4; Q8TA98; Q8TAA2;
DE   RecName: Full=Proteasome subunit alpha type-7-like;
DE            EC=3.4.25.1;
GN   Name=PSMA8; Synonyms=PSMA7L;
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSA7_HUMAN              Reviewed;         248 AA.
AC   O14818; B2R515; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8;
DE   RecName: Full=Proteasome subunit alpha type-7;
DE            EC=3.4.25.1;
DE   AltName: Full=Proteasome subunit RC6-1;
DE   AltName: Full=Proteasome subunit XAPC7;
GN   Name=PSMA7; Synonyms=HSPC;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSAL_HUMAN              Reviewed;         478 AA.
AC   A6NEC2; A8MZ60;
DE   RecName: Full=Puromycin-sensitive aminopeptidase-like protein;
DE            EC=3.4.11.-;
GN   Name=NPEPPSL1;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   PSA_HUMAN               Reviewed;         919 AA.
AC   P55786; Q6P145; Q9NP16; Q9UEM2;
DE   RecName: Full=Puromycin-sensitive aminopeptidase;
DE            Short=PSA;
DE            EC=3.4.11.14;
DE   AltName: Full=Cytosol alanyl aminopeptidase;
DE            Short=AAP-S;
GN   Name=NPEPPS; Synonyms=PSA;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
//
ID   PSB10_HUMAN             Reviewed;         273 AA.
AC   P40306; B2R5J4; Q5U098;
DE   RecName: Full=Proteasome subunit beta type-10;
DE            EC=3.4.25.1;
DE   AltName: Full=Low molecular mass protein 10;
DE   AltName: Full=Macropain subunit MECl-1;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit MECl-1;
DE   AltName: Full=Proteasome MECl-1;
DE   AltName: Full=Proteasome subunit beta-2i;
DE   Flags: Precursor;
GN   Name=PSMB10; Synonyms=LMP10, MECL1;
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB11_HUMAN             Reviewed;         300 AA.
AC   A5LHX3;
DE   RecName: Full=Proteasome subunit beta type-11;
DE            EC=3.4.25.1;
DE   AltName: Full=Proteasome subunit beta-5t;
DE   Flags: Precursor;
GN   Name=PSMB11;
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB1_HUMAN              Reviewed;         241 AA.
AC   P20618; B5BU76; Q9BWA8;
DE   RecName: Full=Proteasome subunit beta type-1;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain subunit C5;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C5;
DE   AltName: Full=Proteasome component C5;
DE   AltName: Full=Proteasome gamma chain;
DE   Flags: Precursor;
GN   Name=PSMB1; Synonyms=PSC5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB2_HUMAN              Reviewed;         201 AA.
AC   P49721; D3DPS0; P31145; Q9BWZ9;
DE   RecName: Full=Proteasome subunit beta type-2;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain subunit C7-I;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C7-I;
DE   AltName: Full=Proteasome component C7-I;
GN   Name=PSMB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB3_HUMAN              Reviewed;         205 AA.
AC   P49720; P31147; Q0P6J7; Q96E27;
DE   RecName: Full=Proteasome subunit beta type-3;
DE            EC=3.4.25.1;
DE   AltName: Full=Proteasome chain 13;
DE   AltName: Full=Proteasome component C10-II;
DE   AltName: Full=Proteasome theta chain;
GN   Name=PSMB3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB4_HUMAN              Reviewed;         264 AA.
AC   P28070; B2R9L3; P31148; Q5SZS5; Q6IBI4; Q969L6;
DE   RecName: Full=Proteasome subunit beta type-4;
DE            EC=3.4.25.1;
DE   AltName: Full=26 kDa prosomal protein;
DE            Short=HsBPROS26;
DE            Short=PROS-26;
DE   AltName: Full=Macropain beta chain;
DE   AltName: Full=Multicatalytic endopeptidase complex beta chain;
DE   AltName: Full=Proteasome beta chain;
DE   AltName: Full=Proteasome chain 3;
DE            Short=HsN3;
DE   Flags: Precursor;
GN   Name=PSMB4; Synonyms=PROS26;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IEA:Ensembl.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB5_HUMAN              Reviewed;         263 AA.
AC   P28074; B2R4N9; B4DUM9; D3DS43; E9PAV2; Q16242; Q6PEW2; Q7Z3B5;
AC   Q86T01; Q9TNN9;
DE   RecName: Full=Proteasome subunit beta type-5;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain epsilon chain;
DE   AltName: Full=Multicatalytic endopeptidase complex epsilon chain;
DE   AltName: Full=Proteasome chain 6;
DE   AltName: Full=Proteasome epsilon chain;
DE   AltName: Full=Proteasome subunit MB1;
DE   AltName: Full=Proteasome subunit X;
DE   Flags: Precursor;
GN   Name=PSMB5; Synonyms=LMPX, MB1, X;
DR   GuidetoPHARMACOLOGY; 2406; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB6_HUMAN              Reviewed;         239 AA.
AC   P28072; Q96J55;
DE   RecName: Full=Proteasome subunit beta type-6;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain delta chain;
DE   AltName: Full=Multicatalytic endopeptidase complex delta chain;
DE   AltName: Full=Proteasome delta chain;
DE   AltName: Full=Proteasome subunit Y;
DE   Flags: Precursor;
GN   Name=PSMB6; Synonyms=LMPY, Y;
DR   GO; GO:0004175; F:endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB7_HUMAN              Reviewed;         277 AA.
AC   Q99436; Q5TBG6; Q96AG8; Q9BWA7;
DE   RecName: Full=Proteasome subunit beta type-7;
DE            EC=3.4.25.1;
DE   AltName: Full=Macropain chain Z;
DE   AltName: Full=Multicatalytic endopeptidase complex chain Z;
DE   AltName: Full=Proteasome subunit Z;
DE   Flags: Precursor;
GN   Name=PSMB7; Synonyms=Z;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB8_HUMAN              Reviewed;         276 AA.
AC   P28062; B0UZC0; Q29824; Q5JNW6; Q5QNR8; Q96J48;
DE   RecName: Full=Proteasome subunit beta type-8;
DE            EC=3.4.25.1;
DE   AltName: Full=Low molecular mass protein 7;
DE   AltName: Full=Macropain subunit C13;
DE   AltName: Full=Multicatalytic endopeptidase complex subunit C13;
DE   AltName: Full=Proteasome component C13;
DE   AltName: Full=Proteasome subunit beta-5i;
DE   AltName: Full=Really interesting new gene 10 protein;
DE   Flags: Precursor;
GN   Name=PSMB8; Synonyms=LMP7, PSMB5i, RING10, Y2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0045444; P:fat cell differentiation; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSB9_HUMAN              Reviewed;         219 AA.
AC   P28065; B0V0T1; Q16523; Q5JNW4;
DE   RecName: Full=Proteasome subunit beta type-9;
DE            EC=3.4.25.1;
DE   AltName: Full=Low molecular mass protein 2;
DE   AltName: Full=Macropain chain 7;
DE   AltName: Full=Multicatalytic endopeptidase complex chain 7;
DE   AltName: Full=Proteasome chain 7;
DE   AltName: Full=Proteasome subunit beta-1i;
DE   AltName: Full=Really interesting new gene 12 protein;
DE   Flags: Precursor;
GN   Name=PSMB9; Synonyms=LMP2, PSMB6i, RING12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSCA_HUMAN              Reviewed;         123 AA.
AC   O43653; Q6UW92;
DE   RecName: Full=Prostate stem cell antigen;
DE   Flags: Precursor;
GN   Name=PSCA; ORFNames=UNQ206/PRO232;
//
ID   PSD10_HUMAN             Reviewed;         226 AA.
AC   O75832; Q5U0B2; Q8IZK9;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 10;
DE   AltName: Full=26S proteasome regulatory subunit p28;
DE   AltName: Full=Gankyrin;
DE   AltName: Full=p28(GANK);
GN   Name=PSMD10;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSD11_HUMAN             Reviewed;         422 AA.
AC   O00231; A8K3I7; E1P663; O00495; Q53FT5;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 11;
DE   AltName: Full=26S proteasome regulatory subunit RPN6;
DE   AltName: Full=26S proteasome regulatory subunit S9;
DE   AltName: Full=26S proteasome regulatory subunit p44.5;
GN   Name=PSMD11;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0043248; P:proteasome assembly; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048863; P:stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSD12_HUMAN             Reviewed;         456 AA.
AC   O00232; A6NP15; Q53HA2; Q6P053;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 12;
DE   AltName: Full=26S proteasome regulatory subunit RPN5;
DE   AltName: Full=26S proteasome regulatory subunit p55;
GN   Name=PSMD12;
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSD13_HUMAN             Reviewed;         376 AA.
AC   Q9UNM6; B3KT15; O75831; Q53XU2; Q9UNV3;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 13;
DE   AltName: Full=26S proteasome regulatory subunit RPN9;
DE   AltName: Full=26S proteasome regulatory subunit S11;
DE   AltName: Full=26S proteasome regulatory subunit p40.5;
GN   Name=PSMD13;
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007127; P:meiosis I; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSD1_HUMAN              Reviewed;        1024 AA.
AC   A5PKW4; B1AKX7; D3DR87; Q15673; Q8IVG0;
DE   RecName: Full=PH and SEC7 domain-containing protein 1;
DE   AltName: Full=Exchange factor for ARF6;
DE   AltName: Full=Pleckstrin homology and SEC7 domain-containing protein 1;
GN   Name=PSD; Synonyms=EFA6, KIAA2011, PSD1, TYL;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   PSD2_HUMAN              Reviewed;         771 AA.
AC   Q9BQI7; D3DQD3; Q8N3J8;
DE   RecName: Full=PH and SEC7 domain-containing protein 2;
DE   AltName: Full=Pleckstrin homology and SEC7 domain-containing protein 2;
GN   Name=PSD2;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   PSD3_HUMAN              Reviewed;        1048 AA.
AC   Q9NYI0; A6NFQ4; E9KL50; Q6B003; Q9Y2F1;
DE   RecName: Full=PH and SEC7 domain-containing protein 3;
DE   AltName: Full=Epididymis tissue protein Li 20mP;
DE   AltName: Full=Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 67;
DE   AltName: Full=Pleckstrin homology and SEC7 domain-containing protein 3;
GN   Name=PSD3; Synonyms=EFA6R, HCA67, KIAA0942;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   PSD4_HUMAN              Reviewed;        1056 AA.
AC   Q8NDX1; A6NEG7; A8K1Y0; O95621; Q4ZG34; Q6GPH8; Q8IYP4;
DE   RecName: Full=PH and SEC7 domain-containing protein 4;
DE   AltName: Full=Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B;
DE            Short=Exchange factor for ARF6 B;
DE   AltName: Full=Pleckstrin homology and SEC7 domain-containing protein 4;
DE   AltName: Full=Telomeric of interleukin-1 cluster protein;
GN   Name=PSD4; Synonyms=EFA6B, TIC;
DR   GO; GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   GO; GO:0043087; P:regulation of GTPase activity; IBA:GOC.
//
ID   PSDE_HUMAN              Reviewed;         310 AA.
AC   O00487; B3KNW2; O00176;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 14;
DE            EC=3.4.19.-;
DE   AltName: Full=26S proteasome regulatory subunit RPN11;
DE   AltName: Full=26S proteasome-associated PAD1 homolog 1;
GN   Name=PSMD14; Synonyms=POH1;
DR   GO; GO:0061133; F:endopeptidase activator activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0070628; F:proteasome binding; IDA:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010950; P:positive regulation of endopeptidase activity; IMP:GOC.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSF1_HUMAN              Reviewed;         196 AA.
AC   Q14691; Q9NQE2; Q9NQI7;
DE   RecName: Full=DNA replication complex GINS protein PSF1;
DE   AltName: Full=GINS complex subunit 1;
GN   Name=GINS1; Synonyms=KIAA0186, PSF1;
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   PSF2_HUMAN              Reviewed;         185 AA.
AC   Q9Y248; D3DUM5; Q6IAG9;
DE   RecName: Full=DNA replication complex GINS protein PSF2;
DE   AltName: Full=GINS complex subunit 2;
GN   Name=GINS2; Synonyms=PSF2; ORFNames=CGI-122, DC5, HSPC037;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   PSF3_HUMAN              Reviewed;         216 AA.
AC   Q9BRX5; B2RDP3; E9PB21; Q9H870;
DE   RecName: Full=DNA replication complex GINS protein PSF3;
DE   AltName: Full=GINS complex subunit 3;
GN   Name=GINS3; Synonyms=PSF3;
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   PSG11_HUMAN             Reviewed;         335 AA.
AC   Q9UQ72; Q13179; Q15242; Q8WW91; Q9UNE4;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 11;
DE            Short=PS-beta-G-11;
DE            Short=PSBG-11;
DE            Short=Pregnancy-specific glycoprotein 11;
DE   AltName: Full=Pregnancy-specific beta-1-glycoprotein 13;
DE            Short=PS-beta-G-13;
DE            Short=PSBG-13;
DE            Short=Pregnancy-specific glycoprotein 13;
DE   Flags: Precursor;
GN   Name=PSG11; Synonyms=PSG13, PSG14;
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   PSG1_HUMAN              Reviewed;         419 AA.
AC   P11464; O75236; P11462; P11463; Q15231; Q15241; Q15243; Q16660;
AC   Q6ICR4; Q9P1W5; Q9UQ79;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 1;
DE            Short=PS-beta-G-1;
DE            Short=PSBG-1;
DE            Short=Pregnancy-specific glycoprotein 1;
DE   AltName: Full=CD66 antigen-like family member F;
DE   AltName: Full=Fetal liver non-specific cross-reactive antigen 1/2;
DE            Short=FL-NCA-1/2;
DE   AltName: Full=PSG95;
DE   AltName: Full=Pregnancy-specific beta-1 glycoprotein C/D;
DE            Short=PS-beta-C/D;
DE   AltName: CD_antigen=CD66f;
DE   Flags: Precursor;
GN   Name=PSG1; Synonyms=B1G1, PSBG1, PSGGA;
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   PSG2_HUMAN              Reviewed;         335 AA.
AC   P11465; Q8TCD9; Q9UEA4; Q9UQ78;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 2;
DE            Short=PS-beta-G-2;
DE            Short=PSBG-2;
DE            Short=Pregnancy-specific glycoprotein 2;
DE   AltName: Full=Pregnancy-specific beta-1 glycoprotein E;
DE            Short=PS-beta-E;
DE   Flags: Precursor;
GN   Name=PSG2; Synonyms=PSBG2;
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; NAS:UniProtKB.
//
ID   PSG4_HUMAN              Reviewed;         419 AA.
AC   Q00888; Q13047; Q13048; Q15234; Q15240; Q9UQ76;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 4;
DE            Short=PS-beta-G-4;
DE            Short=PSBG-4;
DE            Short=Pregnancy-specific glycoprotein 4;
DE   AltName: Full=Pregnancy-specific beta-1-glycoprotein 9;
DE            Short=PS-beta-G-9;
DE            Short=PSBG-9;
DE            Short=Pregnancy-specific glycoprotein 9;
DE   Flags: Precursor;
GN   Name=PSG4; Synonyms=CGM4, PSG9;
DR   GO; GO:0007565; P:female pregnancy; TAS:UniProtKB.
//
ID   PSG3_HUMAN              Reviewed;         428 AA.
AC   Q16557; Q08265; Q9BRW2; Q9UPL4; Q9UQ77;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 3;
DE            Short=PS-beta-G-3;
DE            Short=PSBG-3;
DE            Short=Pregnancy-specific glycoprotein 3;
DE   AltName: Full=Carcinoembryonic antigen SG5;
DE   Flags: Precursor;
GN   Name=PSG3;
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; TAS:UniProtKB.
//
ID   PSG5_HUMAN              Reviewed;         335 AA.
AC   Q15238; Q15239; Q96QJ1; Q9UQ75;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 5;
DE            Short=PS-beta-G-5;
DE            Short=PSBG-5;
DE            Short=Pregnancy-specific glycoprotein 5;
DE   AltName: Full=Fetal liver non-specific cross-reactive antigen 3;
DE            Short=FL-NCA-3;
DE   Flags: Precursor;
GN   Name=PSG5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   PSG6_HUMAN              Reviewed;         435 AA.
AC   Q00889; O75244; Q15224; Q15235; Q549K1;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 6;
DE            Short=PS-beta-G-6;
DE            Short=PSBG-6;
DE            Short=Pregnancy-specific glycoprotein 6;
DE   AltName: Full=Pregnancy-specific beta-1-glycoprotein 10;
DE            Short=PS-beta-G-10;
DE            Short=PSBG-10;
DE            Short=Pregnancy-specific glycoprotein 10;
DE   AltName: Full=Pregnancy-specific beta-1-glycoprotein 12;
DE            Short=PS-beta-G-12;
DE            Short=PSBG-12;
DE            Short=Pregnancy-specific glycoprotein 12;
DE   Flags: Precursor;
GN   Name=PSG6; Synonyms=CGM3, PSG10, PSG12, PSGGB;
DR   GO; GO:0007565; P:female pregnancy; NAS:UniProtKB.
//
ID   PSG8_HUMAN              Reviewed;         426 AA.
AC   Q9UQ74; A5PKV3; B2RPL4; B4DTI6; O60410; Q68CR6;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 8;
DE            Short=PS-beta-G-8;
DE            Short=PSBG-8;
DE            Short=Pregnancy-specific glycoprotein 8;
DE   Flags: Precursor;
GN   Name=PSG8;
//
ID   PSG9_HUMAN              Reviewed;         426 AA.
AC   Q00887; B2R869; Q15236; Q15237; Q8WW78; Q9UQ73;
DE   RecName: Full=Pregnancy-specific beta-1-glycoprotein 9;
DE            Short=PS-beta-G-9;
DE            Short=PSBG-9;
DE            Short=Pregnancy-specific glycoprotein 9;
DE   AltName: Full=PS34;
DE   AltName: Full=Pregnancy-specific beta-1 glycoprotein B;
DE            Short=PS-beta-B;
DE   AltName: Full=Pregnancy-specific beta-1-glycoprotein 11;
DE            Short=PS-beta-G-11;
DE            Short=PSBG-11;
DE            Short=Pregnancy-specific glycoprotein 11;
DE   AltName: Full=Pregnancy-specific glycoprotein 7;
DE            Short=PSG7;
DE   Flags: Precursor;
GN   Name=PSG9; Synonyms=PSG11;
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   PSG7_HUMAN              Reviewed;         419 AA.
AC   Q13046; Q15232;
DE   RecName: Full=Putative pregnancy-specific beta-1-glycoprotein 7;
DE            Short=PS-beta-G-7;
DE            Short=PSBG-7;
DE            Short=Pregnancy-specific glycoprotein 7;
DE   Flags: Precursor;
GN   Name=PSG7;
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   PSIP1_HUMAN             Reviewed;         530 AA.
AC   O75475; D3DRI9; O00256; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6;
DE   RecName: Full=PC4 and SFRS1-interacting protein;
DE   AltName: Full=CLL-associated antigen KW-7;
DE   AltName: Full=Dense fine speckles 70 kDa protein;
DE            Short=DFS 70;
DE   AltName: Full=Lens epithelium-derived growth factor;
DE   AltName: Full=Transcriptional coactivator p75/p52;
GN   Name=PSIP1; Synonyms=DFS70, LEDGF, PSIP2;
DR   GO; GO:0033613; F:activating transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0097100; F:supercoiled DNA binding; ISS:UniProtKB.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0000395; P:mRNA 5'-splice site recognition; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD1_HUMAN             Reviewed;         953 AA.
AC   Q99460; B8ZZH9; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9;
AC   Q86VU1; Q8IV79;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 1;
DE   AltName: Full=26S proteasome regulatory subunit RPN2;
DE   AltName: Full=26S proteasome regulatory subunit S1;
DE   AltName: Full=26S proteasome subunit p112;
GN   Name=PSMD1;
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD2_HUMAN             Reviewed;         908 AA.
AC   Q13200; Q12932; Q15321; Q53XQ4; Q96I12;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 2;
DE   AltName: Full=26S proteasome regulatory subunit RPN1;
DE   AltName: Full=26S proteasome regulatory subunit S2;
DE   AltName: Full=26S proteasome subunit p97;
DE   AltName: Full=Protein 55.11;
DE   AltName: Full=Tumor necrosis factor type 1 receptor-associated protein 2;
GN   Name=PSMD2; Synonyms=TRAP2;
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD3_HUMAN             Reviewed;         534 AA.
AC   O43242; B3KMW9; Q96EI2; Q9BQA4;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 3;
DE   AltName: Full=26S proteasome regulatory subunit RPN3;
DE   AltName: Full=26S proteasome regulatory subunit S3;
DE   AltName: Full=Proteasome subunit p58;
GN   Name=PSMD3;
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:InterPro.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD4_HUMAN             Reviewed;         377 AA.
AC   P55036; D3DV16; Q5VWC5; Q9NS92;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 4;
DE   AltName: Full=26S proteasome regulatory subunit RPN10;
DE   AltName: Full=26S proteasome regulatory subunit S5A;
DE   AltName: Full=Antisecretory factor 1;
DE            Short=AF;
DE            Short=ASF;
DE   AltName: Full=Multiubiquitin chain-binding protein;
GN   Name=PSMD4; Synonyms=MCB1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD5_HUMAN             Reviewed;         504 AA.
AC   Q16401; B4DZM8; Q15045; Q4VXG8;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 5;
DE   AltName: Full=26S protease subunit S5 basic;
DE   AltName: Full=26S proteasome subunit S5B;
GN   Name=PSMD5; Synonyms=KIAA0072;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070682; P:proteasome regulatory particle assembly; TAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:GOC.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD6_HUMAN             Reviewed;         389 AA.
AC   Q15008; A8K2E0; Q6UV22;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 6;
DE   AltName: Full=26S proteasome regulatory subunit RPN7;
DE   AltName: Full=26S proteasome regulatory subunit S10;
DE   AltName: Full=Breast cancer-associated protein SGA-113M;
DE   AltName: Full=Phosphonoformate immuno-associated protein 4;
DE   AltName: Full=Proteasome regulatory particle subunit p44S10;
DE   AltName: Full=p42A;
GN   Name=PSMD6; Synonyms=KIAA0107, PFAAP4;
DR   GO; GO:0016887; F:ATPase activity; NAS:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD7_HUMAN             Reviewed;         324 AA.
AC   P51665; D3DWS9; Q6PKI2; Q96E97;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 7;
DE   AltName: Full=26S proteasome regulatory subunit RPN8;
DE   AltName: Full=26S proteasome regulatory subunit S12;
DE   AltName: Full=Mov34 protein homolog;
DE   AltName: Full=Proteasome subunit p40;
GN   Name=PSMD7; Synonyms=MOV34L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD8_HUMAN             Reviewed;         350 AA.
AC   P48556; B4DX18; Q6P1L7;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 8;
DE   AltName: Full=26S proteasome regulatory subunit RPN12;
DE   AltName: Full=26S proteasome regulatory subunit S14;
DE   AltName: Full=p31;
GN   Name=PSMD8;
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMD9_HUMAN             Reviewed;         223 AA.
AC   O00233; B2RD35; G3V1Q6; Q9BQ42;
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 9;
DE   AltName: Full=26S proteasome regulatory subunit p27;
GN   Name=PSMD9;
DR   GO; GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSME1_HUMAN             Reviewed;         249 AA.
AC   Q06323; A6NJG9; Q6IBM2; Q9UEF4;
DE   RecName: Full=Proteasome activator complex subunit 1;
DE   AltName: Full=11S regulator complex subunit alpha;
DE            Short=REG-alpha;
DE   AltName: Full=Activator of multicatalytic protease subunit 1;
DE   AltName: Full=Interferon gamma up-regulated I-5111 protein;
DE            Short=IGUP I-5111;
DE   AltName: Full=Proteasome activator 28 subunit alpha;
DE            Short=PA28a;
DE            Short=PA28alpha;
GN   Name=PSME1; Synonyms=IFI5111;
DR   GO; GO:0061133; F:endopeptidase activator activity; IEA:Ensembl.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSME2_HUMAN             Reviewed;         239 AA.
AC   Q9UL46; Q15129;
DE   RecName: Full=Proteasome activator complex subunit 2;
DE   AltName: Full=11S regulator complex subunit beta;
DE            Short=REG-beta;
DE   AltName: Full=Activator of multicatalytic protease subunit 2;
DE   AltName: Full=Proteasome activator 28 subunit beta;
DE            Short=PA28b;
DE            Short=PA28beta;
GN   Name=PSME2;
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSME3_HUMAN             Reviewed;         254 AA.
AC   P61289; A8K9A3; O35563; P97373; Q12920; Q13172; Q9BQD9;
DE   RecName: Full=Proteasome activator complex subunit 3;
DE   AltName: Full=11S regulator complex subunit gamma;
DE            Short=REG-gamma;
DE   AltName: Full=Activator of multicatalytic protease subunit 3;
DE   AltName: Full=Ki nuclear autoantigen;
DE   AltName: Full=Proteasome activator 28 subunit gamma;
DE            Short=PA28g;
DE            Short=PA28gamma;
GN   Name=PSME3;
DR   GO; GO:0061133; F:endopeptidase activator activity; IDA:UniProtKB.
DR   GO; GO:0097371; F:MDM2/MDM4 family protein binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010950; P:positive regulation of endopeptidase activity; IDA:GOC.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSME4_HUMAN             Reviewed;        1843 AA.
AC   Q14997; Q1XBG4; Q1XBG5; Q1XBG6; Q2M1Z0; Q6IPR2; Q86XF8;
DE   RecName: Full=Proteasome activator complex subunit 4;
DE   AltName: Full=Proteasome activator PA200;
GN   Name=PSME4; Synonyms=KIAA0077;
DR   GO; GO:0070577; F:lysine-acetylated histone binding; ISS:UniProtKB.
DR   GO; GO:0016504; F:peptidase activator activity; ISS:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035093; P:spermatogenesis, exchange of chromosomal proteins; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMF1_HUMAN             Reviewed;         271 AA.
AC   Q92530; A0AVQ9; D3DVW3; Q9H4I1;
DE   RecName: Full=Proteasome inhibitor PI31 subunit;
DE            Short=hPI31;
GN   Name=PSMF1;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0070628; F:proteasome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; NAS:GOC.
DR   GO; GO:1901799; P:negative regulation of proteasomal protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   PSMG1_HUMAN             Reviewed;         288 AA.
AC   O95456; B5BUN2; Q6FHA3; Q6FHD3; Q6S713;
DE   RecName: Full=Proteasome assembly chaperone 1;
DE            Short=PAC-1;
DE   AltName: Full=Chromosome 21 leucine-rich protein;
DE            Short=C21-LRP;
DE   AltName: Full=Down syndrome critical region protein 2;
GN   Name=PSMG1; Synonyms=C21LRP, DSCR2, PAC1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043248; P:proteasome assembly; IDA:UniProtKB.
//
ID   PSMG2_HUMAN             Reviewed;         264 AA.
AC   Q969U7; B0YJB3; Q6IAH4;
DE   RecName: Full=Proteasome assembly chaperone 2;
DE            Short=PAC-2;
DE   AltName: Full=Hepatocellular carcinoma-susceptibility protein 3;
DE   AltName: Full=Tumor necrosis factor superfamily member 5-induced protein 1;
GN   Name=PSMG2; Synonyms=HCCA3, PAC2, TNFSF5IP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043248; P:proteasome assembly; IDA:UniProtKB.
//
ID   PSMG3_HUMAN             Reviewed;         122 AA.
AC   Q9BT73; A4D216; A8MPW2;
DE   RecName: Full=Proteasome assembly chaperone 3;
DE            Short=PAC-3;
DE            Short=hPAC3;
GN   Name=PSMG3; Synonyms=C7orf48, PAC3;
//
ID   PSMG4_HUMAN             Reviewed;         123 AA.
AC   Q5JS54; C9J2F8; F8WBZ2; Q5JS53; Q5JS56;
DE   RecName: Full=Proteasome assembly chaperone 4;
DE            Short=PAC-4;
DE            Short=hPAC4;
GN   Name=PSMG4; Synonyms=C6orf86, PAC4;
//
ID   PSN1_HUMAN              Reviewed;         467 AA.
AC   P49768; B2R6D3; O95465; Q14762; Q15719; Q15720; Q96P33; Q9UIF0;
DE   RecName: Full=Presenilin-1;
DE            Short=PS-1;
DE            EC=3.4.23.-;
DE   AltName: Full=Protein S182;
DE   Contains:
DE     RecName: Full=Presenilin-1 NTF subunit;
DE   Contains:
DE     RecName: Full=Presenilin-1 CTF subunit;
DE   Contains:
DE     RecName: Full=Presenilin-1 CTF12;
DE              Short=PS1-CTF12;
GN   Name=PSEN1; Synonyms=AD3, PS1, PSNL1;
DR   GuidetoPHARMACOLOGY; 2402; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0045296; F:cadherin binding; IBA:RefGenome.
DR   GO; GO:0005262; F:calcium channel activity; IMP:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:MGI.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; TAS:HGNC.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IEA:Ensembl.
DR   GO; GO:0034205; P:beta-amyloid formation; IEA:Ensembl.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IBA:RefGenome.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0048854; P:brain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021870; P:Cajal-Retzius cell differentiation; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006816; P:calcium ion transport; IBA:RefGenome.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IMP:MGI.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0021795; P:cerebral cortex cell migration; IEA:Ensembl.
DR   GO; GO:0015871; P:choline transport; IEA:Ensembl.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IGI:UniProtKB.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0015813; P:L-glutamate transport; IEA:Ensembl.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:HGNC.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:Ensembl.
DR   GO; GO:0002573; P:myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:2000059; P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:HGNC.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:HGNC.
DR   GO; GO:0050820; P:positive regulation of coagulation; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; IEA:Ensembl.
DR   GO; GO:0016485; P:protein processing; IDA:HGNC.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0042325; P:regulation of phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0060075; P:regulation of resting membrane potential; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0043589; P:skin morphogenesis; IEA:Ensembl.
DR   GO; GO:0051563; P:smooth endoplasmic reticulum calcium ion homeostasis; IBA:RefGenome.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0016080; P:synaptic vesicle targeting; IEA:Ensembl.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   PSN2_HUMAN              Reviewed;         448 AA.
AC   P49810; A8K8D4; B1AP21; Q96P32;
DE   RecName: Full=Presenilin-2;
DE            Short=PS-2;
DE            EC=3.4.23.-;
DE   AltName: Full=AD3LP;
DE   AltName: Full=AD5;
DE   AltName: Full=E5-1;
DE   AltName: Full=STM-2;
DE   Contains:
DE     RecName: Full=Presenilin-2 NTF subunit;
DE   Contains:
DE     RecName: Full=Presenilin-2 CTF subunit;
GN   Name=PSEN2; Synonyms=AD4, PS2, PSNL2, STM2;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0004175; F:endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; TAS:HGNC.
DR   GO; GO:0042640; P:anagen; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IBA:RefGenome.
DR   GO; GO:0048854; P:brain morphogenesis; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IBA:RefGenome.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0040011; P:locomotion; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:HGNC.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0002573; P:myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:HGNC.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:HGNC.
DR   GO; GO:0050820; P:positive regulation of coagulation; IEA:Ensembl.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0016485; P:protein processing; IDA:HGNC.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0002286; P:T cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   PSPB_HUMAN              Reviewed;         381 AA.
AC   P07988; Q96R04;
DE   RecName: Full=Pulmonary surfactant-associated protein B;
DE            Short=SP-B;
DE   AltName: Full=18 kDa pulmonary-surfactant protein;
DE   AltName: Full=6 kDa protein;
DE   AltName: Full=Pulmonary surfactant-associated proteolipid SPL(Phe);
DE   Flags: Precursor;
GN   Name=SFTPB; Synonyms=SFTP3;
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
//
ID   PSPC1_HUMAN             Reviewed;         523 AA.
AC   Q8WXF1; Q5JTQ3; Q8NCZ9; Q8WXE8; Q9NV36;
DE   RecName: Full=Paraspeckle component 1;
DE   AltName: Full=Paraspeckle protein 1;
GN   Name=PSPC1; Synonyms=PSP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PSPC_HUMAN              Reviewed;         197 AA.
AC   P11686; A6XNE4; B2RE00; E9PGX3; P11687; Q12793; Q7Z5D0;
DE   RecName: Full=Pulmonary surfactant-associated protein C;
DE            Short=SP-C;
DE   AltName: Full=Pulmonary surfactant-associated proteolipid SPL(Val);
DE   AltName: Full=SP5;
DE   Flags: Precursor;
GN   Name=SFTPC; Synonyms=SFTP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0071732; P:cellular response to nitric oxide; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:UniProtKB-KW.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0070848; P:response to growth factor; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0070741; P:response to interleukin-6; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
//
ID   PSPHL_HUMAN             Reviewed;          72 AA.
AC   O15172; Q86U85;
DE   RecName: Full=Putative phosphoserine phosphatase-like protein;
DE   AltName: Full=L-3-phosphoserine-phosphatase homolog;
GN   Name=PSPHP1; Synonyms=CO9, PSPHL;
DR   GO; GO:0004647; F:phosphoserine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0016311; P:dephosphorylation; TAS:GOC.
//
ID   PSPN_HUMAN              Reviewed;         156 AA.
AC   O60542;
DE   RecName: Full=Persephin;
DE            Short=PSP;
DE   Flags: Precursor;
GN   Name=PSPN;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   PSRC1_HUMAN             Reviewed;         363 AA.
AC   Q6PGN9; Q5T2Z3; Q6ZTI8; Q71MG3; Q9BV77;
DE   RecName: Full=Proline/serine-rich coiled-coil protein 1;
GN   Name=PSRC1; Synonyms=DDA3; ORFNames=FP3214;
DR   GO; GO:0008017; F:microtubule binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; ISS:BHF-UCL.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; ISS:BHF-UCL.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0060236; P:regulation of mitotic spindle organization; IDA:UniProtKB.
//
ID   PSTK_HUMAN              Reviewed;         348 AA.
AC   Q8IV42; Q6ZSS9;
DE   RecName: Full=L-seryl-tRNA(Sec) kinase;
DE            EC=2.7.1.164;
DE   AltName: Full=O-phosphoseryl-tRNA(Sec) kinase;
GN   Name=PSTK; Synonyms=C10orf89;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; IEA:Ensembl.
DR   GO; GO:0001514; P:selenocysteine incorporation; IEA:Ensembl.
DR   GO; GO:0097056; P:selenocysteinyl-tRNA(Sec) biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   PSYR_HUMAN              Reviewed;         337 AA.
AC   Q8IYL9; O75819;
DE   RecName: Full=Psychosine receptor;
DE   AltName: Full=G-protein coupled receptor 65;
DE   AltName: Full=T-cell death-associated gene 8 protein;
GN   Name=GPR65; Synonyms=TDAG8;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:BHF-UCL.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:BHF-UCL.
DR   GO; GO:0010447; P:response to acidity; IDA:BHF-UCL.
//
ID   PT100_HUMAN             Reviewed;          73 AA.
AC   P0DJ07;
DE   RecName: Full=Protein PET100 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=PET100; Synonyms=C19orf79;
//
ID   PT117_HUMAN             Reviewed;          81 AA.
AC   Q6UWS5;
DE   RecName: Full=Protein PET117 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=PET117; ORFNames=UNQ607/PRO1194;
//
ID   PTAFR_HUMAN             Reviewed;         342 AA.
AC   P25105; A3KMC8; A8K2H5;
DE   RecName: Full=Platelet-activating factor receptor;
DE            Short=PAF-R;
DE            Short=PAFr;
GN   Name=PTAFR; Synonyms=PAFR;
DR   GuidetoPHARMACOLOGY; 334; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IEA:Ensembl.
DR   GO; GO:0001875; F:lipopolysaccharide receptor activity; IEA:Ensembl.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0004992; F:platelet activating factor receptor activity; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0032959; P:inositol trisphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IDA:UniProtKB.
//
ID   PTAR1_HUMAN             Reviewed;         402 AA.
AC   Q7Z6K3; Q5T7V5; Q5T7V6;
DE   RecName: Full=Protein prenyltransferase alpha subunit repeat-containing protein 1;
GN   Name=PTAR1;
DR   GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR   GO; GO:0018342; P:protein prenylation; IEA:InterPro.
//
ID   PTBP1_HUMAN             Reviewed;         531 AA.
AC   P26599; Q9BUQ0;
DE   RecName: Full=Polypyrimidine tract-binding protein 1;
DE            Short=PTB;
DE   AltName: Full=57 kDa RNA-binding protein PPTB-1;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein I;
DE            Short=hnRNP I;
GN   Name=PTBP1; Synonyms=PTB;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008187; F:poly-pyrimidine tract binding; TAS:ProtInc.
DR   GO; GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0051148; P:negative regulation of muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0033119; P:negative regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   PTBP2_HUMAN             Reviewed;         531 AA.
AC   Q9UKA9; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76;
DE   RecName: Full=Polypyrimidine tract-binding protein 2;
DE   AltName: Full=Neural polypyrimidine tract-binding protein;
DE   AltName: Full=Neurally-enriched homolog of PTB;
DE   AltName: Full=PTB-like protein;
GN   Name=PTBP2; Synonyms=NPTB, PTB, PTBLP;
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:Ensembl.
DR   GO; GO:0033119; P:negative regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:2000177; P:regulation of neural precursor cell proliferation; IEA:Ensembl.
//
ID   PTBP3_HUMAN             Reviewed;         552 AA.
AC   O95758; B1ALY2; B1ALY3; B1ALY5; B1ALY6; B3KME7; Q68DB9; Q86YB3;
AC   Q86YH9;
DE   RecName: Full=Polypyrimidine tract-binding protein 3;
DE   AltName: Full=Regulator of differentiation 1;
DE            Short=Rod1;
GN   Name=PTBP3; Synonyms=ROD1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0033119; P:negative regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   PTC2_HUMAN              Reviewed;        1203 AA.
AC   Q9Y6C5; O95341; O95856; Q53Z57; Q5QP87; Q6UX14;
DE   RecName: Full=Protein patched homolog 2;
DE            Short=PTC2;
GN   Name=PTCH2; ORFNames=UNQ560/PRO1121/PRO57079;
DR   GO; GO:0097108; F:hedgehog family protein binding; IPI:BHF-UCL.
DR   GO; GO:0008158; F:hedgehog receptor activity; TAS:BHF-UCL.
DR   GO; GO:0005119; F:smoothened binding; IPI:BHF-UCL.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0042633; P:hair cycle; IEA:Ensembl.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   PTC1_HUMAN              Reviewed;        1447 AA.
AC   Q13635; A3KBI9; E9PEJ8; Q13463; Q5R1U7; Q5R1U9; Q5R1V0; Q5VZC0;
AC   Q5VZC2; Q86XG7;
DE   RecName: Full=Protein patched homolog 1;
DE            Short=PTC;
DE            Short=PTC1;
GN   Name=PTCH1; Synonyms=PTCH;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0030332; F:cyclin binding; IPI:BHF-UCL.
DR   GO; GO:0097108; F:hedgehog family protein binding; IPI:BHF-UCL.
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005119; F:smoothened binding; IPI:BHF-UCL.
DR   GO; GO:0007420; P:brain development; ISS:BHF-UCL.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0061005; P:cell differentiation involved in kidney development; IEA:Ensembl.
DR   GO; GO:0072203; P:cell proliferation involved in metanephros development; IEA:Ensembl.
DR   GO; GO:0071397; P:cellular response to cholesterol; IMP:BHF-UCL.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0043616; P:keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060603; P:mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0051782; P:negative regulation of cell division; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; ISS:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0021997; P:neural plate axis specification; ISS:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0021532; P:neural tube patterning; IMP:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060037; P:pharyngeal system development; IMP:BHF-UCL.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0016485; P:protein processing; ISS:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0072001; P:renal system development; IEP:UniProtKB.
DR   GO; GO:0010157; P:response to chlorate; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEP:UniProtKB.
DR   GO; GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0061053; P:somite development; IMP:BHF-UCL.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
//
ID   PTCA_HUMAN              Reviewed;         206 AA.
AC   Q14761; B2R512; O00643; Q6I9S6;
DE   RecName: Full=Protein tyrosine phosphatase receptor type C-associated protein;
DE            Short=PTPRC-associated protein;
DE   AltName: Full=CD45-associated protein;
DE            Short=CD45-AP;
DE   AltName: Full=Lymphocyte phosphatase-associated phosphoprotein;
GN   Name=PTPRCAP; Synonyms=LPAP;
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
//
ID   PTCD1_HUMAN             Reviewed;         700 AA.
AC   O75127; Q3ZB78; Q66K60; Q9UDV2;
DE   RecName: Full=Pentatricopeptide repeat-containing protein 1, mitochondrial;
GN   Name=PTCD1; Synonyms=KIAA0632;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0042780; P:tRNA 3'-end processing; IDA:UniProtKB.
//
ID   PTCD2_HUMAN             Reviewed;         388 AA.
AC   Q8WV60; Q6IA65; Q9H9R0;
DE   RecName: Full=Pentatricopeptide repeat-containing protein 2, mitochondrial;
GN   Name=PTCD2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0050684; P:regulation of mRNA processing; ISS:UniProtKB.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
//
ID   PTCD3_HUMAN             Reviewed;         689 AA.
AC   Q96EY7; A6NHD2; D6W5M1; Q597H0; Q658Y9; Q9BUZ8; Q9NWL0;
DE   RecName: Full=Pentatricopeptide repeat domain-containing protein 3, mitochondrial;
DE   AltName: Full=28S ribosomal protein S39, mitochondrial;
DE            Short=MRP-S39;
DE   AltName: Full=Transformation-related gene 15 protein;
DE            Short=TRG-15;
DE   Flags: Precursor;
GN   Name=PTCD3; Synonyms=MRPS39; ORFNames=TRG15;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IDA:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   PTCRA_HUMAN             Reviewed;         281 AA.
AC   Q6ISU1; Q5TFZ7;
DE   RecName: Full=Pre T-cell antigen receptor alpha;
DE            Short=pT-alpha;
DE            Short=pTa;
DE   AltName: Full=pT-alpha-TCR;
DE   Flags: Precursor;
GN   Name=PTCRA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
//
ID   PTEN_HUMAN              Reviewed;         403 AA.
AC   P60484; B2R904; O00633; O02679; Q6ICT7;
DE   RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE            EC=3.1.3.67;
DE   AltName: Full=Mutated in multiple advanced cancers 1;
DE   AltName: Full=Phosphatase and tensin homolog;
GN   Name=PTEN; Synonyms=MMAC1, TEP1;
DR   GO; GO:0010997; F:anaphase-promoting complex binding; IPI:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0051717; F:inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0051800; F:phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IDA:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0032286; P:central nervous system myelin maintenance; ISS:BHF-UCL.
DR   GO; GO:0021955; P:central nervous system neuron axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0021542; P:dentate gyrus development; ISS:BHF-UCL.
DR   GO; GO:0043542; P:endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; ISS:BHF-UCL.
DR   GO; GO:0045475; P:locomotor rhythm; ISS:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; ISS:BHF-UCL.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0060179; P:male mating behavior; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0033555; P:multicellular organismal response to stress; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0090344; P:negative regulation of cell aging; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045792; P:negative regulation of cell size; ISS:BHF-UCL.
DR   GO; GO:0031658; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0061002; P:negative regulation of dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0031642; P:negative regulation of myelination; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; TAS:BHF-UCL.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0090071; P:negative regulation of ribosome biogenesis; IEA:Ensembl.
DR   GO; GO:2000808; P:negative regulation of synaptic vesicle clustering; ISS:BHF-UCL.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.
DR   GO; GO:0060134; P:prepulse inhibition; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0060736; P:prostate gland growth; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0002902; P:regulation of B cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0032535; P:regulation of cellular component size; ISS:BHF-UCL.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0033032; P:regulation of myeloid cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:UniProtKB.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0060024; P:rhythmic synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035176; P:social behavior; ISS:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0060074; P:synapse maturation; ISS:BHF-UCL.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   PTER_HUMAN              Reviewed;         349 AA.
AC   Q96BW5; B0YJ77; B3KTF5; D3DRU0; Q9BY46;
DE   RecName: Full=Phosphotriesterase-related protein;
DE            EC=3.1.-.-;
DE   AltName: Full=Parathion hydrolase-related protein;
DE            Short=hPHRP;
GN   Name=PTER;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009056; P:catabolic process; IEA:InterPro.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
//
ID   PTF1A_HUMAN             Reviewed;         328 AA.
AC   Q7RTS3; Q9HC25;
DE   RecName: Full=Pancreas transcription factor 1 subunit alpha;
DE   AltName: Full=Class A basic helix-loop-helix protein 29;
DE            Short=bHLHa29;
DE   AltName: Full=Pancreas-specific transcription factor 1a;
DE   AltName: Full=bHLH transcription factor p48;
DE   AltName: Full=p48 DNA-binding subunit of transcription factor PTF1;
DE            Short=PTF1-p48;
GN   Name=PTF1A; Synonyms=BHLHA29, PTF1P48;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0035881; P:amacrine cell differentiation; ISS:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; IMP:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0031018; P:endocrine pancreas development; TAS:Reactome.
DR   GO; GO:0031017; P:exocrine pancreas development; ISS:UniProtKB.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IMP:UniProtKB.
DR   GO; GO:0061074; P:regulation of neural retina development; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009888; P:tissue development; IDA:UniProtKB.
//
ID   PTG3L_HUMAN             Reviewed;         166 AA.
AC   E9PB15;
DE   RecName: Full=Putative protein PTGES3L;
DE   AltName: Full=Prostaglandin E synthase 3-like;
GN   Name=PTGES3L;
//
ID   PTGDS_HUMAN             Reviewed;         190 AA.
AC   P41222; B2R727; Q5SQ10; Q7M4P3; Q9UC22; Q9UCC9; Q9UCD9;
DE   RecName: Full=Prostaglandin-H2 D-isomerase;
DE            EC=5.3.99.2;
DE   AltName: Full=Beta-trace protein;
DE   AltName: Full=Cerebrin-28;
DE   AltName: Full=Glutathione-independent PGD synthase;
DE   AltName: Full=Lipocalin-type prostaglandin-D synthase;
DE   AltName: Full=Prostaglandin-D2 synthase;
DE            Short=PGD2 synthase;
DE            Short=PGDS;
DE            Short=PGDS2;
DE   Flags: Precursor;
GN   Name=PTGDS; Synonyms=PDS;
DR   GO; GO:0005504; F:fatty acid binding; IDA:UniProtKB.
DR   GO; GO:0004667; F:prostaglandin-D synthase activity; IDA:UniProtKB.
DR   GO; GO:0005501; F:retinoid binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; ISS:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; ISS:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; ISS:UniProtKB.
//
ID   PTGES_HUMAN             Reviewed;         152 AA.
AC   O14684; O14900; Q5SZC0;
DE   RecName: Full=Prostaglandin E synthase;
DE            EC=5.3.99.3;
DE   AltName: Full=Microsomal glutathione S-transferase 1-like 1;
DE            Short=MGST1-L1;
DE   AltName: Full=Microsomal prostaglandin E synthase 1;
DE            Short=MPGES-1;
DE   AltName: Full=p53-induced gene 12 protein;
GN   Name=PTGES; Synonyms=MGST1L1, MPGES1, PGES, PIG12;
DR   GO; GO:0043295; F:glutathione binding; IDA:UniProtKB.
DR   GO; GO:0050220; F:prostaglandin-E synthase activity; IDA:UniProtKB.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; TAS:ProtInc.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PTGIS_HUMAN             Reviewed;         500 AA.
AC   Q16647; Q3MII8; Q9HAX2; Q9HAX3; Q9HAX4;
DE   RecName: Full=Prostacyclin synthase;
DE            EC=5.3.99.4;
DE   AltName: Full=Prostaglandin I2 synthase;
GN   Name=PTGIS; Synonyms=CYP8, CYP8A1;
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0008116; F:prostaglandin-I synthase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071354; P:cellular response to interleukin-6; IEP:UniProtKB.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0006690; P:icosanoid metabolic process; TAS:Reactome.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:1900119; P:positive regulation of execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0035360; P:positive regulation of peroxisome proliferator activated receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   PTH2R_HUMAN             Reviewed;         550 AA.
AC   P49190; Q8N429;
DE   RecName: Full=Parathyroid hormone 2 receptor;
DE            Short=PTH2 receptor;
DE   Flags: Precursor;
GN   Name=PTH2R; Synonyms=PTHR2;
DR   GuidetoPHARMACOLOGY; 332; -.
DR   GO; GO:0004991; F:parathyroid hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   PTH1R_HUMAN             Reviewed;         593 AA.
AC   Q03431; Q2M1U3;
DE   RecName: Full=Parathyroid hormone/parathyroid hormone-related peptide receptor;
DE   AltName: Full=PTH/PTHrP type I receptor;
DE            Short=PTH/PTHr receptor;
DE   AltName: Full=Parathyroid hormone 1 receptor;
DE            Short=PTH1 receptor;
DE   Flags: Precursor;
GN   Name=PTH1R; Synonyms=PTHR, PTHR1;
DR   GuidetoPHARMACOLOGY; 331; -.
DR   GO; GO:0004991; F:parathyroid hormone receptor activity; IDA:UniProtKB.
DR   GO; GO:0017046; F:peptide hormone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0060732; P:positive regulation of inositol phosphate biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   PTGR2_HUMAN             Reviewed;         351 AA.
AC   Q8N8N7; Q3L8A4; Q6MZH8;
DE   RecName: Full=Prostaglandin reductase 2;
DE            Short=PRG-2;
DE            EC=1.3.1.48;
DE   AltName: Full=15-oxoprostaglandin 13-reductase;
DE   AltName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein 1;
GN   Name=PTGR2; Synonyms=ZADH1;
DR   GO; GO:0036132; F:13-prostaglandin reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047522; F:15-oxoprostaglandin 13-oxidase activity; IDA:UniProtKB.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.
//
ID   PTGR1_HUMAN             Reviewed;         329 AA.
AC   Q14914; A8K0N2; B4DPK3; F5GY50; Q8IYQ0; Q9H1X6;
DE   RecName: Full=Prostaglandin reductase 1;
DE            Short=PRG-1;
DE            EC=1.3.1.-;
DE   AltName: Full=15-oxoprostaglandin 13-reductase;
DE            EC=1.3.1.48;
DE   AltName: Full=NADP-dependent leukotriene B4 12-hydroxydehydrogenase;
DE            EC=1.3.1.74;
GN   Name=PTGR1; Synonyms=LTB4DH;
DR   GO; GO:0036132; F:13-prostaglandin reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047522; F:15-oxoprostaglandin 13-oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032440; F:2-alkenal reductase [NAD(P)] activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0006691; P:leukotriene metabolic process; NAS:UniProtKB.
DR   GO; GO:2001300; P:lipoxin metabolic process; TAS:Reactome.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PTH2_HUMAN              Reviewed;         179 AA.
AC   Q9Y3E5; B3KUY4; Q9NTE5;
DE   RecName: Full=Peptidyl-tRNA hydrolase 2, mitochondrial;
DE            Short=PTH 2;
DE            EC=3.1.1.29;
DE   AltName: Full=Bcl-2 inhibitor of transcription 1;
DE   Flags: Precursor;
GN   Name=PTRH2; Synonyms=BIT1, PTH2; ORFNames=CGI-147;
DR   GO; GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:2000210; P:positive regulation of anoikis; IMP:UniProtKB.
//
ID   PTHB1_HUMAN             Reviewed;         887 AA.
AC   Q3SYG4; E9PDC9; P78514; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854;
AC   Q9Y699; Q9Y6A0;
DE   RecName: Full=Protein PTHB1;
DE   AltName: Full=Bardet-Biedl syndrome 9 protein;
DE   AltName: Full=Parathyroid hormone-responsive B1 gene protein;
GN   Name=BBS9; Synonyms=PTHB1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   PTHD1_HUMAN             Reviewed;         888 AA.
AC   Q96NR3; B4DQH0; Q0IJ60; Q6P6B8;
DE   RecName: Full=Patched domain-containing protein 1;
GN   Name=PTCHD1;
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IDA:UniProtKB.
//
ID   PTHD2_HUMAN             Reviewed;        1392 AA.
AC   Q9P2K9; Q5VTU9; Q9UJD6;
DE   RecName: Full=Patched domain-containing protein 2;
DE   AltName: Full=Protein dispatched homolog 3;
GN   Name=PTCHD2; Synonyms=DISP3, KIAA1337;
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0032368; P:regulation of lipid transport; NAS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; NAS:UniProtKB.
//
ID   PTHD3_HUMAN             Reviewed;         767 AA.
AC   Q3KNS1; I3L499; Q6ZU28;
DE   RecName: Full=Patched domain-containing protein 3;
DE   AltName: Full=Patched-related protein;
GN   Name=PTCHD3; Synonyms=PTR;
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
DR   GO; GO:0007286; P:spermatid development; NAS:UniProtKB.
//
ID   PTHD4_HUMAN             Reviewed;         846 AA.
AC   Q6ZW05; B4DRK3; Q5T884;
DE   RecName: Full=Patched domain-containing protein 4;
GN   Name=PTCHD4; Synonyms=C6orf138;
DR   GO; GO:0008158; F:hedgehog receptor activity; IEA:InterPro.
//
ID   PTHR_HUMAN              Reviewed;         177 AA.
AC   P12272; Q15251; Q6FH74;
DE   RecName: Full=Parathyroid hormone-related protein;
DE            Short=PTH-rP;
DE            Short=PTHrP;
DE   AltName: Full=Parathyroid hormone-like protein;
DE            Short=PLP;
DE   Contains:
DE     RecName: Full=PTHrP[1-36];
DE   Contains:
DE     RecName: Full=PTHrP[38-94];
DE   Contains:
DE     RecName: Full=Osteostatin;
DE     AltName: Full=PTHrP[107-139];
DE   Flags: Precursor;
GN   Name=PTHLH; Synonyms=PTHRP;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0051428; F:peptide hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:MGI.
DR   GO; GO:0046058; P:cAMP metabolic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0060649; P:mammary gland bud elongation; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IDA:MGI.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0060659; P:nipple sheath formation; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0016485; P:protein processing; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:MGI.
DR   GO; GO:0001501; P:skeletal system development; IDA:MGI.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
//
ID   PTHY_HUMAN              Reviewed;         115 AA.
AC   P01270; Q4VB48; Q9UD38;
DE   RecName: Full=Parathyroid hormone;
DE            Short=PTH;
DE   AltName: Full=Parathormone;
DE   AltName: Full=Parathyrin;
DE   Flags: Precursor;
GN   Name=PTH;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0051428; F:peptide hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045453; P:bone resorption; NAS:UniProtKB.
DR   GO; GO:0046058; P:cAMP metabolic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0034645; P:cellular macromolecule biosynthetic process; IDA:MGI.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008628; P:hormone-mediated apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:MGI.
DR   GO; GO:0046326; P:positive regulation of glucose import; IDA:UniProtKB.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:MGI.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0071774; P:response to fibroblast growth factor; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0071107; P:response to parathyroid hormone; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IMP:GOC.
//
ID   PTH_HUMAN               Reviewed;         214 AA.
AC   Q86Y79;
DE   RecName: Full=Probable peptidyl-tRNA hydrolase;
DE            Short=PTH;
DE            EC=3.1.1.29;
GN   Name=PTRH1; Synonyms=C9orf115;
DR   GO; GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   PTK6_HUMAN              Reviewed;         451 AA.
AC   Q13882; B2RCR3; B4DW46; Q58F01;
DE   RecName: Full=Protein-tyrosine kinase 6;
DE            EC=2.7.10.2;
DE   AltName: Full=Breast tumor kinase;
DE   AltName: Full=Tyrosine-protein kinase BRK;
GN   Name=PTK6; Synonyms=BRK;
DR   GuidetoPHARMACOLOGY; 2182; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0060575; P:intestinal epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045926; P:negative regulation of growth; IEA:Ensembl.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0042503; P:tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.
DR   GO; GO:0042506; P:tyrosine phosphorylation of Stat5 protein; IDA:UniProtKB.
//
ID   PTK7_HUMAN              Reviewed;        1070 AA.
AC   Q13308; A8K974; B7Z477; E9PFZ5; Q13417; Q5T650; Q6IQ54; Q8NFA5;
AC   Q8NFA6; Q8NFA7; Q8NFA8;
DE   RecName: Full=Inactive tyrosine-protein kinase 7;
DE   AltName: Full=Colon carcinoma kinase 4;
DE            Short=CCK-4;
DE   AltName: Full=Protein-tyrosine kinase 7;
DE   AltName: Full=Pseudo tyrosine kinase receptor 7;
DE   AltName: Full=Tyrosine-protein kinase-like 7;
DE   Flags: Precursor;
GN   Name=PTK7; Synonyms=CCK4;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0003401; P:axis elongation; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0060026; P:convergent extension; IEA:Ensembl.
DR   GO; GO:0045198; P:establishment of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0001736; P:establishment of planar polarity; IEA:Ensembl.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   PTMA_HUMAN              Reviewed;         111 AA.
AC   P06454; Q15249; Q15592;
DE   RecName: Full=Prothymosin alpha;
DE   Contains:
DE     RecName: Full=Prothymosin alpha, N-terminally processed;
DE   Contains:
DE     RecName: Full=Thymosin alpha-1;
GN   Name=PTMA; Synonyms=TMSA;
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   PTMS_HUMAN              Reviewed;         102 AA.
AC   P20962;
DE   RecName: Full=Parathymosin;
GN   Name=PTMS;
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   PTN11_HUMAN             Reviewed;         597 AA.
AC   Q06124; A8K1D9; Q96HD7;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 11;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase 1D;
DE            Short=PTP-1D;
DE   AltName: Full=Protein-tyrosine phosphatase 2C;
DE            Short=PTP-2C;
DE   AltName: Full=SH-PTP2;
DE            Short=SHP-2;
DE            Short=Shp2;
DE   AltName: Full=SH-PTP3;
GN   Name=PTPN11; Synonyms=PTP2C, SHPTP2;
DR   GO; GO:0005158; F:insulin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0036302; P:atrioventricular canal development; IMP:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IMP:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000077; P:DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038127; P:ERBB signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048806; P:genitalia development; IMP:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IMP:BHF-UCL.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048839; P:inner ear development; IMP:BHF-UCL.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0048609; P:multicellular organismal reproductive process; IEA:Ensembl.
DR   GO; GO:0051463; P:negative regulation of cortisol secretion; IEA:Ensembl.
DR   GO; GO:0060125; P:negative regulation of growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0046825; P:regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   PTN12_HUMAN             Reviewed;         780 AA.
AC   Q05209; A4D1C5; B4DKY2; E9PBR5; E9PEH9; Q16130; Q59FD6; Q75MN8;
AC   Q86XU4;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 12;
DE            EC=3.1.3.48;
DE   AltName: Full=PTP-PEST;
DE   AltName: Full=Protein-tyrosine phosphatase G1;
DE            Short=PTPG1;
GN   Name=PTPN12;
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN13_HUMAN             Reviewed;        2485 AA.
AC   Q12923; B2RTR0; Q15159; Q15263; Q15264; Q15265; Q15674; Q16826;
AC   Q8IWH7; Q9NYN9; Q9UDA8;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 13;
DE            EC=3.1.3.48;
DE   AltName: Full=Fas-associated protein-tyrosine phosphatase 1;
DE            Short=FAP-1;
DE   AltName: Full=PTP-BAS;
DE   AltName: Full=Protein-tyrosine phosphatase 1E;
DE            Short=PTP-E1;
DE            Short=hPTPE1;
DE   AltName: Full=Protein-tyrosine phosphatase PTPL1;
GN   Name=PTPN13; Synonyms=PNP1, PTP1E, PTPL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN14_HUMAN             Reviewed;        1187 AA.
AC   Q15678; Q5VSI0;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 14;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase pez;
GN   Name=PTPN14; Synonyms=PEZ, PTPD2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0003712; F:transcription cofactor activity; IMP:UniProtKB.
DR   GO; GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IMP:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0046825; P:regulation of protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PTN18_HUMAN             Reviewed;         460 AA.
AC   Q99952; B4E1E6; Q53P42;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 18;
DE            EC=3.1.3.48;
DE   AltName: Full=Brain-derived phosphatase;
GN   Name=PTPN18; Synonyms=BDP1;
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN1_HUMAN              Reviewed;         435 AA.
AC   P18031; Q5TGD8; Q9BQV9; Q9NQQ4;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 1;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase 1B;
DE            Short=PTP-1B;
GN   Name=PTPN1; Synonyms=PTP1B;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0035791; P:platelet-derived growth factor receptor-beta signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030100; P:regulation of endocytosis; IDA:UniProtKB.
DR   GO; GO:1902202; P:regulation of hepatocyte growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0009966; P:regulation of signal transduction; IMP:UniProtKB.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   PTN20_HUMAN             Reviewed;         420 AA.
AC   Q4JDL3; A6NNH8; B7ZKV3; Q4JDG6; Q4JDK1; Q4JDK5; Q4JDK6; Q4JDK8;
AC   Q4JDK9; Q4JDL0; Q4JDL1; Q4JDL4; Q4JDL5; Q4JDL6; Q4JDL7; Q4JDL8;
AC   Q5RJ33; Q5T1G3;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 20;
DE            Short=hPTPN20;
DE            EC=3.1.3.48;
GN   Name=PTPN20A;
GN   and
GN   Name=PTPN20B;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
//
ID   PTN21_HUMAN             Reviewed;        1174 AA.
AC   Q16825;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 21;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase D1;
GN   Name=PTPN21; Synonyms=PTPD1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN22_HUMAN             Reviewed;         807 AA.
AC   Q9Y2R2; A0N0K6; B1ALC8; D4NZ71; E9PLD8; E9PPI1; O95063; O95064;
AC   Q6IPX8; Q8WVM1;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 22;
DE            EC=3.1.3.48;
DE   AltName: Full=Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP;
DE   AltName: Full=Lymphoid phosphatase;
DE            Short=LyP;
DE   AltName: Full=PEST-domain phosphatase;
DE            Short=PEP;
GN   Name=PTPN22; Synonyms=PTPN8;
DR   GO; GO:0019900; F:kinase binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0035644; P:phosphoanandamide dephosphorylation; ISS:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050855; P:regulation of B cell receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.
DR   GO; GO:0032817; P:regulation of natural killer cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0030217; P:T cell differentiation; ISS:BHF-UCL.
//
ID   PTN2_HUMAN              Reviewed;         415 AA.
AC   P17706; A8K955; A8MXU3; K7ENG3; Q96AU5; Q96HR2;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 2;
DE            EC=3.1.3.48;
DE   AltName: Full=T-cell protein-tyrosine phosphatase;
DE            Short=TCPTP;
GN   Name=PTPN2; Synonyms=PTPT;
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050922; P:negative regulation of chemotaxis; ISS:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060336; P:negative regulation of interferon-gamma-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:1902206; P:negative regulation of interleukin-2-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:1902215; P:negative regulation of interleukin-4-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0070104; P:negative regulation of interleukin-6-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0010888; P:negative regulation of lipid storage; ISS:UniProtKB.
DR   GO; GO:1902227; P:negative regulation of macrophage colony-stimulating factor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; ISS:UniProtKB.
DR   GO; GO:2000587; P:negative regulation of platelet-derived growth factor receptor-beta signaling pathway; ISS:UniProtKB.
DR   GO; GO:1902233; P:negative regulation of positive thymic T cell selection; ISS:UniProtKB.
DR   GO; GO:1902212; P:negative regulation of prolactin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060339; P:negative regulation of type I interferon-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0042512; P:negative regulation of tyrosine phosphorylation of Stat1 protein; IMP:UniProtKB.
DR   GO; GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; IDA:UniProtKB.
DR   GO; GO:0042524; P:negative regulation of tyrosine phosphorylation of Stat5 protein; ISS:UniProtKB.
DR   GO; GO:0042527; P:negative regulation of tyrosine phosphorylation of Stat6 protein; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; ISS:UniProtKB.
DR   GO; GO:1902202; P:regulation of hepatocyte growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030217; P:T cell differentiation; ISS:UniProtKB.
//
ID   PTN23_HUMAN             Reviewed;        1636 AA.
AC   Q9H3S7; A8K0D7; Q7KZF8; Q8N6Z5; Q9BSR5; Q9P257; Q9UG03; Q9UMZ4;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 23;
DE            EC=3.1.3.48;
DE   AltName: Full=His domain-containing protein tyrosine phosphatase;
DE            Short=HD-PTP;
DE   AltName: Full=Protein tyrosine phosphatase TD14;
DE            Short=PTP-TD14;
GN   Name=PTPN23; Synonyms=KIAA1471;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:InterPro.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:UniProtKB.
//
ID   PTN3_HUMAN              Reviewed;         913 AA.
AC   P26045; A0AUW9; E7EN99; E9PGU7;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 3;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase H1;
DE            Short=PTP-H1;
GN   Name=PTPN3; Synonyms=PTPH1;
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0001784; F:phosphotyrosine binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:BHF-UCL.
//
ID   PTN4_HUMAN              Reviewed;         926 AA.
AC   P29074; B2RBV8; Q9UDA7;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 4;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase MEG1;
DE            Short=MEG;
DE            Short=PTPase-MEG1;
GN   Name=PTPN4;
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN5_HUMAN              Reviewed;         565 AA.
AC   P54829; B3KXG7; B7Z386; B7ZAF5; D3DQY7; Q6P1Z2; Q8N2A1; Q8NDP8;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 5;
DE            EC=3.1.3.48;
DE   AltName: Full=Neural-specific protein-tyrosine phosphatase;
DE   AltName: Full=Striatum-enriched protein-tyrosine phosphatase;
DE            Short=STEP;
GN   Name=PTPN5;
DR   GO; GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
//
ID   PTN6_HUMAN              Reviewed;         595 AA.
AC   P29350; A8K306; G3V0F8; Q969V8; Q9UK67;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 6;
DE            EC=3.1.3.48;
DE   AltName: Full=Hematopoietic cell protein-tyrosine phosphatase;
DE   AltName: Full=Protein-tyrosine phosphatase 1C;
DE            Short=PTP-1C;
DE   AltName: Full=Protein-tyrosine phosphatase SHP-1;
DE   AltName: Full=SH-PTP1;
GN   Name=PTPN6; Synonyms=HCP, PTP1C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:Reactome.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0045577; P:regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   PTN7_HUMAN              Reviewed;         360 AA.
AC   P35236; B3KXE1; Q53XK4; Q5SXQ0; Q5SXQ1; Q9BV05;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 7;
DE            EC=3.1.3.48;
DE   AltName: Full=Hematopoietic protein-tyrosine phosphatase;
DE            Short=HEPTP;
DE   AltName: Full=Protein-tyrosine phosphatase LC-PTP;
GN   Name=PTPN7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN9_HUMAN              Reviewed;         593 AA.
AC   P43378; Q53XR9;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type 9;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase MEG2;
DE            Short=PTPase MEG2;
GN   Name=PTPN9;
DR   GO; GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTN_HUMAN               Reviewed;         168 AA.
AC   P21246; Q5U0B0; Q6ICQ5; Q9UCC6;
DE   RecName: Full=Pleiotrophin;
DE            Short=PTN;
DE   AltName: Full=Heparin-binding brain mitogen;
DE            Short=HBBM;
DE   AltName: Full=Heparin-binding growth factor 8;
DE            Short=HBGF-8;
DE   AltName: Full=Heparin-binding growth-associated molecule;
DE            Short=HB-GAM;
DE   AltName: Full=Heparin-binding neurite outgrowth-promoting factor 1;
DE            Short=HBNF-1;
DE   AltName: Full=Osteoblast-specific factor 1;
DE            Short=OSF-1;
DE   Flags: Precursor;
GN   Name=PTN; Synonyms=HBNF1, NEGF1;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
//
ID   PTOV1_HUMAN             Reviewed;         416 AA.
AC   Q86YD1; Q6UXX7; Q96BU3; Q9HBN4; Q9NYL1;
DE   RecName: Full=Prostate tumor-overexpressed gene 1 protein;
DE            Short=PTOV-1;
DE   AltName: Full=Activator interaction domain-containing protein 2;
GN   Name=PTOV1; Synonyms=ACID2; ORFNames=PP642, UNQ6127/PRO20092;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PTPA_HUMAN              Reviewed;         358 AA.
AC   Q15257; A2A347; A9IZU4; B4DXM4; Q15258; Q53GZ3; Q5TZQ2; Q9BUK1;
AC   Q9NNZ7; Q9NNZ8; Q9NNZ9;
DE   RecName: Full=Serine/threonine-protein phosphatase 2A activator;
DE            EC=5.2.1.8;
DE   AltName: Full=PP2A, subunit B', PR53 isoform;
DE   AltName: Full=Phosphotyrosyl phosphatase activator;
DE            Short=PTPA;
DE   AltName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit 4;
DE   AltName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B';
GN   Name=PPP2R4; Synonyms=PTPA;
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
DR   GO; GO:0046982; F:protein heterodimerization activity; TAS:HGNC.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:HGNC.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:HGNC.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; IDA:HGNC.
DR   GO; GO:0008160; F:protein tyrosine phosphatase activator activity; IDA:HGNC.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0030472; P:mitotic spindle organization in nucleus; IBA:RefGenome.
DR   GO; GO:0032515; P:negative regulation of phosphoprotein phosphatase activity; IDA:HGNC.
DR   GO; GO:0035308; P:negative regulation of protein dephosphorylation; IDA:HGNC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:HGNC.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:HGNC.
DR   GO; GO:0006457; P:protein folding; IEA:UniProtKB-KW.
DR   GO; GO:0000413; P:protein peptidyl-prolyl isomerization; IBA:GOC.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IDA:HGNC.
//
ID   PTPC1_HUMAN             Reviewed;         754 AA.
AC   A2A3K4; Q5T3M4; Q6NXE8; Q8IWM1; Q8N1X4; Q8N9F5;
DE   RecName: Full=Protein tyrosine phosphatase domain-containing protein 1;
DE            EC=3.1.3.-;
GN   Name=PTPDC1; Synonyms=PTP9Q22;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
//
ID   PTPM1_HUMAN             Reviewed;         201 AA.
AC   Q8WUK0; E9PAT8; Q7Z557; Q96CR2; Q9BXV8;
DE   RecName: Full=Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1;
DE            EC=3.1.3.27;
DE   AltName: Full=PTEN-like phosphatase;
DE   AltName: Full=Phosphoinositide lipid phosphatase;
DE   AltName: Full=Protein-tyrosine phosphatase mitochondrial 1;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPMT1; Synonyms=MOSP, PLIP; ORFNames=PNAS-129;
DR   GO; GO:0008962; F:phosphatidylglycerophosphatase activity; ISS:UniProtKB.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IBA:RefGenome.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0046855; P:inositol phosphate dephosphorylation; IBA:RefGenome.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PTPR2_HUMAN             Reviewed;        1015 AA.
AC   Q92932; E9PC57; Q8N4I5; Q92662; Q9Y4F8; Q9Y4I6;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase N2;
DE            Short=R-PTP-N2;
DE            EC=3.1.3.48;
DE   AltName: Full=Islet cell autoantigen-related protein;
DE            Short=IAR;
DE            Short=ICAAR;
DE   AltName: Full=Phogrin;
DE   Flags: Precursor;
GN   Name=PTPRN2; Synonyms=KIAA0387;
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTPRA_HUMAN             Reviewed;         802 AA.
AC   P18433; A8K2G8; D3DVX5; Q14513; Q7Z2I2; Q96TD9;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase alpha;
DE            Short=Protein-tyrosine phosphatase alpha;
DE            Short=R-PTP-alpha;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRA; Synonyms=PTPA, PTPRL2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
//
ID   PTPRB_HUMAN             Reviewed;        1997 AA.
AC   P23467; B7ZKS8; B7ZKT0; C9JX87; F5H3G6; Q14D85; Q3MIV7;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase beta;
DE            Short=Protein-tyrosine phosphatase beta;
DE            Short=R-PTP-beta;
DE            EC=3.1.3.48;
DE   AltName: Full=Vascular endothelial protein tyrosine phosphatase;
DE            Short=VE-PTP;
DE   Flags: Precursor;
GN   Name=PTPRB; Synonyms=PTPB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0016311; P:dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTPRC_HUMAN             Reviewed;        1304 AA.
AC   P08575; A8K7W6; Q16614; Q9H0Y6;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase C;
DE            EC=3.1.3.48;
DE   AltName: Full=Leukocyte common antigen;
DE            Short=L-CA;
DE   AltName: Full=T200;
DE   AltName: CD_antigen=CD45;
DE   Flags: Precursor;
GN   Name=PTPRC; Synonyms=CD45;
DR   GuidetoPHARMACOLOGY; 1852; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0042100; P:B cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048539; P:bone marrow development; IMP:UniProtKB.
DR   GO; GO:0044770; P:cell cycle phase transition; IMP:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IMP:UniProtKB.
DR   GO; GO:0002378; P:immunoglobulin biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IMP:UniProtKB.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0001915; P:negative regulation of T cell mediated cytotoxicity; ISS:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0050857; P:positive regulation of antigen receptor-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:2000473; P:positive regulation of hematopoietic stem cell migration; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; NAS:UniProtKB.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0048864; P:stem cell development; IMP:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
//
ID   PTPRD_HUMAN             Reviewed;        1912 AA.
AC   P23468; B1ALA0; F5GWT7; Q3KPJ0; Q3KPJ1; Q3KPJ2;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase delta;
DE            Short=Protein-tyrosine phosphatase delta;
DE            Short=R-PTP-delta;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRD;
DR   GO; GO:0050839; F:cell adhesion molecule binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; NAS:ProtInc.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0097105; P:presynaptic membrane assembly; ISS:BHF-UCL.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
//
ID   PTPRE_HUMAN             Reviewed;         700 AA.
AC   P23469; Q13345; Q5VWH3; Q5VWH4; Q96KQ6;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase epsilon;
DE            Short=Protein-tyrosine phosphatase epsilon;
DE            Short=R-PTP-epsilon;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRE;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0033003; P:regulation of mast cell activation; IEA:Ensembl.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; IEA:Ensembl.
//
ID   PTPRF_HUMAN             Reviewed;        1907 AA.
AC   P10586; D3DPX6; D3DPX7; Q5T021; Q5T022; Q5W9G2; Q86WS0;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase F;
DE            EC=3.1.3.48;
DE   AltName: Full=Leukocyte common antigen related;
DE            Short=LAR;
DE   Flags: Precursor;
GN   Name=PTPRF; Synonyms=LAR;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
//
ID   PTPRG_HUMAN             Reviewed;        1445 AA.
AC   P23470; B2RU12; B7ZLX5; Q15623; Q59EE0; Q68DU5;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase gamma;
DE            Short=Protein-tyrosine phosphatase gamma;
DE            Short=R-PTP-gamma;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRG; Synonyms=PTPG;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   PTPRH_HUMAN             Reviewed;        1115 AA.
AC   Q9HD43; C9JCH2; Q15426; Q2NKN9; Q2NKP0;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase H;
DE            Short=R-PTP-H;
DE            EC=3.1.3.48;
DE   AltName: Full=Stomach cancer-associated protein tyrosine phosphatase 1;
DE            Short=SAP-1;
DE   AltName: Full=Transmembrane-type protein-tyrosine phosphatase type H;
DE   Flags: Precursor;
GN   Name=PTPRH; Synonyms=SAP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTPRJ_HUMAN             Reviewed;        1337 AA.
AC   Q12913; Q15255; Q6P4H4; Q8NHM2; Q9UDA9;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase eta;
DE            Short=Protein-tyrosine phosphatase eta;
DE            Short=R-PTP-eta;
DE            EC=3.1.3.48;
DE   AltName: Full=Density-enhanced phosphatase 1;
DE            Short=DEP-1;
DE   AltName: Full=HPTP eta;
DE   AltName: Full=Protein-tyrosine phosphatase receptor type J;
DE            Short=R-PTP-J;
DE   AltName: CD_antigen=CD148;
DE   Flags: Precursor;
GN   Name=PTPRJ; Synonyms=DEP1;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0070097; F:delta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0016791; F:phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0060242; P:contact inhibition; NAS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:2000272; P:negative regulation of receptor activity; IEA:Ensembl.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:0010572; P:positive regulation of platelet activation; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   PTPRK_HUMAN             Reviewed;        1439 AA.
AC   Q15262; B2RTQ8; B7ZMG0; Q14763; Q5TG10; Q5TG11;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase kappa;
DE            Short=Protein-tyrosine phosphatase kappa;
DE            Short=R-PTP-kappa;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRK; Synonyms=PTPK;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
//
ID   PTPRN_HUMAN             Reviewed;         979 AA.
AC   Q16849; B4DK12; F5GZS3; Q08319; Q53QD6; Q6NSL1;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase-like N;
DE            Short=R-PTP-N;
DE   AltName: Full=Islet cell antigen 512;
DE            Short=ICA 512;
DE   AltName: Full=Islet cell autoantigen 3;
DE   AltName: Full=PTP IA-2;
DE   Flags: Precursor;
GN   Name=PTPRN; Synonyms=ICA3, ICA512;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030507; F:spectrin binding; IPI:BHF-UCL.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
//
ID   PTPRM_HUMAN             Reviewed;        1452 AA.
AC   P28827; A7MBN1; D3DUH8; J3QL11;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase mu;
DE            Short=Protein-tyrosine phosphatase mu;
DE            Short=R-PTP-mu;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRM; Synonyms=PTPRL1;
DR   GO; GO:0045296; F:cadherin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; IMP:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   PTPRO_HUMAN             Reviewed;        1216 AA.
AC   Q16827; A0AV39; Q13101; Q8IYG3; Q9UBF0; Q9UBT5;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase O;
DE            Short=R-PTP-O;
DE            EC=3.1.3.48;
DE   AltName: Full=Glomerular epithelial protein 1;
DE   AltName: Full=Protein tyrosine phosphatase U2;
DE            Short=PTP-U2;
DE            Short=PTPase U2;
DE   Flags: Precursor;
GN   Name=PTPRO; Synonyms=GLEPP1, PTPU2;
DR   GO; GO:0016791; F:phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0017147; F:Wnt-protein binding; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032835; P:glomerulus development; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0002548; P:monocyte chemotaxis; IMP:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.
DR   GO; GO:0003105; P:negative regulation of glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0090260; P:negative regulation of retinal ganglion cell axon guidance; ISS:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IMP:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0003093; P:regulation of glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0036060; P:slit diaphragm assembly; ISS:UniProtKB.
//
ID   PTPRQ_HUMAN             Reviewed;        2332 AA.
AC   Q9UMZ3;
DE   RecName: Full=Phosphatidylinositol phosphatase PTPRQ;
DE            EC=3.1.3.-;
DE   AltName: Full=Receptor-type tyrosine-protein phosphatase Q;
DE            Short=PTP-RQ;
DE            Short=R-PTP-Q;
DE            EC=3.1.3.48;
DE   Flags: Precursor;
GN   Name=PTPRQ;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IDA:UniProtKB.
//
ID   PTPRR_HUMAN             Reviewed;         657 AA.
AC   Q15256; B2R5Z7; B7Z3J1; F5GXR7; O00342; Q92682; Q9UE65;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase R;
DE            Short=R-PTP-R;
DE            EC=3.1.3.48;
DE   AltName: Full=Ch-1PTPase;
DE   AltName: Full=NC-PTPCOM1;
DE   AltName: Full=Protein-tyrosine phosphatase PCPTP1;
DE   Flags: Precursor;
GN   Name=PTPRR; Synonyms=ECPTP, PTPRQ;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEP:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
//
ID   PTPRS_HUMAN             Reviewed;        1948 AA.
AC   Q13332; O75255; O75870; Q15718; Q16341; Q2M3R7;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase S;
DE            Short=R-PTP-S;
DE            EC=3.1.3.48;
DE   AltName: Full=Receptor-type tyrosine-protein phosphatase sigma;
DE            Short=R-PTP-sigma;
DE   Flags: Precursor;
GN   Name=PTPRS;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0022038; P:corpus callosum development; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
//
ID   PTPRT_HUMAN             Reviewed;        1441 AA.
AC   O14522; A8E4R6; O43655; O75664; Q5W0X9; Q5W0Y1; Q9BR24; Q9BR28;
AC   Q9H0Y8; Q9NTL1; Q9NU72; Q9UBD2; Q9UJL7;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase T;
DE            Short=R-PTP-T;
DE            EC=3.1.3.48;
DE   AltName: Full=Receptor-type tyrosine-protein phosphatase rho;
DE            Short=RPTP-rho;
DE   Flags: Precursor;
GN   Name=PTPRT; Synonyms=KIAA0283;
DR   GO; GO:0045294; F:alpha-catenin binding; IDA:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0045296; F:cadherin binding; IPI:UniProtKB.
DR   GO; GO:0070097; F:delta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0045295; F:gamma-catenin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IMP:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.
//
ID   PTPRU_HUMAN             Reviewed;        1446 AA.
AC   Q92729; A6H8L1; O00197; P78399; Q59HA4; Q5SYU4; Q5SYU5; Q92735;
AC   Q92850;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase U;
DE            Short=R-PTP-U;
DE            EC=3.1.3.48;
DE   AltName: Full=Pancreatic carcinoma phosphatase 2;
DE            Short=PCP-2;
DE   AltName: Full=Protein-tyrosine phosphatase J;
DE            Short=PTP-J;
DE            Short=hPTP-J;
DE   AltName: Full=Protein-tyrosine phosphatase pi;
DE            Short=PTP pi;
DE   AltName: Full=Protein-tyrosine phosphatase receptor omicron;
DE            Short=PTP-RO;
DE   AltName: Full=Receptor-type protein-tyrosine phosphatase psi;
DE            Short=R-PTP-psi;
DE   Flags: Precursor;
GN   Name=PTPRU; Synonyms=FMI, PCP2, PTPRO;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0034109; P:homotypic cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; NAS:UniProtKB.
//
ID   PTPRZ_HUMAN             Reviewed;        2315 AA.
AC   P23471; A4D0W5; C9JFM0; O76043; Q9UDR6;
DE   RecName: Full=Receptor-type tyrosine-protein phosphatase zeta;
DE            Short=R-PTP-zeta;
DE            EC=3.1.3.48;
DE   AltName: Full=Protein-tyrosine phosphatase receptor type Z polypeptide 1;
DE   AltName: Full=Protein-tyrosine phosphatase receptor type Z polypeptide 2;
DE   AltName: Full=R-PTP-zeta-2;
DE   Flags: Precursor;
GN   Name=PTPRZ1; Synonyms=HTPZP2, PTPRZ, PTPRZ2, PTPZ;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; ISS:UniProtKB.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; ISS:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0070445; P:regulation of oligodendrocyte progenitor proliferation; ISS:UniProtKB.
//
ID   PTPS_HUMAN              Reviewed;         145 AA.
AC   Q03393; B0YJ87; Q8WVG8;
DE   RecName: Full=6-pyruvoyl tetrahydrobiopterin synthase;
DE            Short=PTP synthase;
DE            Short=PTPS;
DE            EC=4.2.3.12;
GN   Name=PTS;
DR   GO; GO:0003874; F:6-pyruvoyltetrahydropterin synthase activity; TAS:Reactome.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; TAS:ProtInc.
//
ID   PTRD1_HUMAN             Reviewed;         140 AA.
AC   Q6GMV3;
DE   RecName: Full=Putative peptidyl-tRNA hydrolase PTRHD1;
DE            EC=3.1.1.29;
DE   AltName: Full=Peptidyl-tRNA hydrolase domain-containing protein 1;
GN   Name=PTRHD1; Synonyms=C2orf79;
DR   GO; GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
//
ID   PTRF_HUMAN              Reviewed;         390 AA.
AC   Q6NZI2; B2RAW7; O00535; Q6GMY1; Q96H74; Q9BT85; Q9HAP4;
DE   RecName: Full=Polymerase I and transcript release factor;
DE   AltName: Full=Cavin-1;
GN   Name=PTRF; ORFNames=FKSG13;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042134; F:rRNA primary transcript binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; IDA:UniProtKB.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; IDA:UniProtKB.
//
ID   PTSS1_HUMAN             Reviewed;         473 AA.
AC   P48651;
DE   RecName: Full=Phosphatidylserine synthase 1;
DE            Short=PSS-1;
DE            Short=PtdSer synthase 1;
DE            EC=2.7.8.29;
DE   AltName: Full=Serine-exchange enzyme I;
GN   Name=PTDSS1; Synonyms=KIAA0024, PSSA;
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006659; P:phosphatidylserine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PTSS2_HUMAN             Reviewed;         487 AA.
AC   Q9BVG9;
DE   RecName: Full=Phosphatidylserine synthase 2;
DE            Short=PSS-2;
DE            Short=PtdSer synthase 2;
DE            EC=2.7.8.29;
DE   AltName: Full=Serine-exchange enzyme II;
GN   Name=PTDSS2; Synonyms=PSS2;
DR   GO; GO:0003882; F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity; IEA:Ensembl.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006659; P:phosphatidylserine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PTTG1_HUMAN             Reviewed;         202 AA.
AC   O95997;
DE   RecName: Full=Securin;
DE   AltName: Full=Esp1-associated protein;
DE   AltName: Full=Pituitary tumor-transforming gene 1 protein;
DE            Short=Tumor-transforming protein 1;
DE            Short=hPTTG;
GN   Name=PTTG1; Synonyms=EAP1, PTTG, TUTR1;
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; NAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   PTTG3_HUMAN             Reviewed;         202 AA.
AC   Q9NZH4; O95356;
DE   RecName: Full=Putative pituitary tumor-transforming gene 3 protein;
DE            Short=hPTTG3;
DE   AltName: Full=Securin-3;
DE   AltName: Full=rcPTTG1;
GN   Name=PTTG3P; Synonyms=PTTG3;
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0006259; P:DNA metabolic process; IEA:InterPro.
//
ID   PTTG2_HUMAN             Reviewed;         202 AA.
AC   Q9NZH5; O95355; Q6NTC9; Q9UNJ6;
DE   RecName: Full=Securin-2;
DE   AltName: Full=Pituitary tumor-transforming gene 2 protein;
GN   Name=PTTG2;
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0006259; P:DNA metabolic process; IEA:InterPro.
//
ID   PTTG_HUMAN              Reviewed;         180 AA.
AC   P53801; B2RDP7; D3DSL9; Q9NS09;
DE   RecName: Full=Pituitary tumor-transforming gene 1 protein-interacting protein;
DE   AltName: Full=Pituitary tumor-transforming gene protein-binding factor;
DE            Short=PBF;
DE            Short=PTTG-binding factor;
DE   Flags: Precursor;
GN   Name=PTTG1IP; Synonyms=C21orf1, C21orf3;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:UniProtKB.
//
ID   PTX3_HUMAN              Reviewed;         381 AA.
AC   P26022; B2R6T6; Q38M82;
DE   RecName: Full=Pentraxin-related protein PTX3;
DE   AltName: Full=Pentaxin-related protein PTX3;
DE   AltName: Full=Tumor necrosis factor alpha-induced protein 5;
DE            Short=TNF alpha-induced protein 5;
DE   AltName: Full=Tumor necrosis factor-inducible gene 14 protein;
DE            Short=TSG-14;
DE   Flags: Precursor;
GN   Name=PTX3; Synonyms=TNFAIP5, TSG14;
DR   GO; GO:0001872; F:(1->3)-beta-D-glucan binding; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008228; P:opsonization; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0001878; P:response to yeast; IEA:Ensembl.
//
ID   PTX4_HUMAN              Reviewed;         478 AA.
AC   Q96A99;
DE   RecName: Full=Pentraxin-4;
DE   Flags: Precursor;
GN   Name=PTX4; Synonyms=C16orf38;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   PUF60_HUMAN             Reviewed;         559 AA.
AC   Q9UHX1; A8K8K8; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UJY7;
DE   RecName: Full=Poly(U)-binding-splicing factor PUF60;
DE   AltName: Full=60 kDa poly(U)-binding-splicing factor;
DE   AltName: Full=FUSE-binding protein-interacting repressor;
DE            Short=FBP-interacting repressor;
DE   AltName: Full=Ro-binding protein 1;
DE            Short=RoBP1;
DE   AltName: Full=Siah-binding protein 1;
DE            Short=Siah-BP1;
GN   Name=PUF60; Synonyms=FIR, ROBPI, SIAHBP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PUM1_HUMAN              Reviewed;        1186 AA.
AC   Q14671; A8K6W4; B4DG92; D3DPN3; E9PCJ0; Q53HH5; Q5VXY7; Q9HAN1;
DE   RecName: Full=Pumilio homolog 1;
DE            Short=HsPUM;
DE            Short=Pumilio-1;
GN   Name=PUM1; Synonyms=KIAA0099, PUMH1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   PUM2_HUMAN              Reviewed;        1066 AA.
AC   Q8TB72; B3KSL0; B4E2B6; D6W527; O00234; Q53TV7; Q8WY43; Q9HAN2;
DE   RecName: Full=Pumilio homolog 2;
DE            Short=Pumilio-2;
GN   Name=PUM2; Synonyms=KIAA0235, PUMH2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0034063; P:stress granule assembly; IEA:Ensembl.
//
ID   PUR1_HUMAN              Reviewed;         517 AA.
AC   Q06203;
DE   RecName: Full=Amidophosphoribosyltransferase;
DE            Short=ATase;
DE            EC=2.4.2.14;
DE   AltName: Full=Glutamine phosphoribosylpyrophosphate amidotransferase;
DE            Short=GPAT;
DE   Flags: Precursor;
GN   Name=PPAT; Synonyms=GPAT;
DR   GuidetoPHARMACOLOGY; 2761; -.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004044; F:amidophosphoribosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006543; P:glutamine catabolic process; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; IEA:InterPro.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; TAS:ProtInc.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PUR2_HUMAN              Reviewed;        1010 AA.
AC   P22102; A8K945; A8KA32; D3DSF3; D3DSF4; O14659; Q52M77;
DE   RecName: Full=Trifunctional purine biosynthetic protein adenosine-3;
DE   Includes:
DE     RecName: Full=Phosphoribosylamine--glycine ligase;
DE              EC=6.3.4.13;
DE     AltName: Full=Glycinamide ribonucleotide synthetase;
DE              Short=GARS;
DE     AltName: Full=Phosphoribosylglycinamide synthetase;
DE   Includes:
DE     RecName: Full=Phosphoribosylformylglycinamidine cyclo-ligase;
DE              EC=6.3.3.1;
DE     AltName: Full=AIR synthase;
DE              Short=AIRS;
DE     AltName: Full=Phosphoribosyl-aminoimidazole synthetase;
DE   Includes:
DE     RecName: Full=Phosphoribosylglycinamide formyltransferase;
DE              EC=2.1.2.2;
DE     AltName: Full=5'-phosphoribosylglycinamide transformylase;
DE     AltName: Full=GAR transformylase;
DE              Short=GART;
GN   Name=GART; Synonyms=PGFT, PRGS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004641; F:phosphoribosylformylglycinamidine cyclo-ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004644; F:phosphoribosylglycinamide formyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0003360; P:brainstem development; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0006544; P:glycine metabolic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; IEA:InterPro.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0010035; P:response to inorganic substance; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:Ensembl.
//
ID   PUR4_HUMAN              Reviewed;        1338 AA.
AC   O15067; A6H8V8;
DE   RecName: Full=Phosphoribosylformylglycinamidine synthase;
DE            Short=FGAM synthase;
DE            Short=FGAMS;
DE            EC=6.3.5.3;
DE   AltName: Full=Formylglycinamide ribotide amidotransferase;
DE            Short=FGARAT;
DE   AltName: Full=Formylglycinamide ribotide synthetase;
GN   Name=PFAS; Synonyms=KIAA0361;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IDA:UniProtKB.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PUR6_HUMAN              Reviewed;         425 AA.
AC   P22234; E9PDH9; Q68CQ5;
DE   RecName: Full=Multifunctional protein ADE2;
DE   Includes:
DE     RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase;
DE              EC=6.3.2.6;
DE     AltName: Full=SAICAR synthetase;
DE   Includes:
DE     RecName: Full=Phosphoribosylaminoimidazole carboxylase;
DE              EC=4.1.1.21;
DE     AltName: Full=AIR carboxylase;
DE              Short=AIRC;
GN   Name=PAICS; Synonyms=ADE2, AIRC, PAIS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; TAS:Reactome.
DR   GO; GO:0004639; F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009113; P:purine nucleobase biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PUR8_HUMAN              Reviewed;         484 AA.
AC   P30566; B0QY76; O75495; Q5TI34;
DE   RecName: Full=Adenylosuccinate lyase;
DE            Short=ASL;
DE            EC=4.3.2.2;
DE   AltName: Full=Adenylosuccinase;
DE            Short=ASase;
GN   Name=ADSL; Synonyms=AMPS;
DR   GO; GO:0070626; F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004018; F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity; IDA:UniProtKB.
DR   GO; GO:0044208; P:'de novo' AMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009060; P:aerobic respiration; IEA:Ensembl.
DR   GO; GO:0006167; P:AMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IC:UniProtKB.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PUR9_HUMAN              Reviewed;         592 AA.
AC   P31939; A8K202; E9PBU3; Q13856; Q53S28;
DE   RecName: Full=Bifunctional purine biosynthesis protein PURH;
DE   Includes:
DE     RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase;
DE              EC=2.1.2.3;
DE     AltName: Full=5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase;
DE     AltName: Full=AICAR transformylase;
DE   Includes:
DE     RecName: Full=IMP cyclohydrolase;
DE              EC=3.5.4.10;
DE     AltName: Full=ATIC;
DE     AltName: Full=IMP synthase;
DE     AltName: Full=Inosinicase;
GN   Name=ATIC; Synonyms=PURH; ORFNames=OK/SW-cl.86;
DR   GO; GO:0003937; F:IMP cyclohydrolase activity; TAS:Reactome.
DR   GO; GO:0004643; F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity; TAS:Reactome.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0003360; P:brainstem development; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0046452; P:dihydrofolate metabolic process; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0010035; P:response to inorganic substance; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:Ensembl.
//
ID   PURA1_HUMAN             Reviewed;         457 AA.
AC   Q8N142; Q86TT6; Q8N714;
DE   RecName: Full=Adenylosuccinate synthetase isozyme 1;
DE            Short=AMPSase 1;
DE            Short=AdSS 1;
DE            EC=6.3.4.4;
DE   AltName: Full=Adenylosuccinate synthetase, basic isozyme;
DE   AltName: Full=Adenylosuccinate synthetase, muscle isozyme;
DE            Short=M-type adenylosuccinate synthetase;
DE   AltName: Full=IMP--aspartate ligase 1;
GN   Name=ADSSL1; Synonyms=ADSS1;
DR   GO; GO:0004019; F:adenylosuccinate synthase activity; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0042301; F:phosphate ion binding; NAS:UniProtKB.
DR   GO; GO:0044208; P:'de novo' AMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006167; P:AMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006531; P:aspartate metabolic process; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:Ensembl.
DR   GO; GO:0002376; P:immune system process; NAS:UniProtKB.
DR   GO; GO:0046040; P:IMP metabolic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PURA2_HUMAN             Reviewed;         456 AA.
AC   P30520; B1AQM5; Q96EG7;
DE   RecName: Full=Adenylosuccinate synthetase isozyme 2;
DE            Short=AMPSase 2;
DE            Short=AdSS 2;
DE            EC=6.3.4.4;
DE   AltName: Full=Adenylosuccinate synthetase, acidic isozyme;
DE   AltName: Full=Adenylosuccinate synthetase, liver isozyme;
DE            Short=L-type adenylosuccinate synthetase;
DE   AltName: Full=IMP--aspartate ligase 2;
GN   Name=ADSS; Synonyms=ADSS2;
DR   GO; GO:0004019; F:adenylosuccinate synthase activity; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0042301; F:phosphate ion binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044208; P:'de novo' AMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006167; P:AMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006531; P:aspartate metabolic process; IEA:Ensembl.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:Ensembl.
DR   GO; GO:0002376; P:immune system process; NAS:UniProtKB.
DR   GO; GO:0046040; P:IMP metabolic process; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; TAS:Reactome.
DR   GO; GO:0060359; P:response to ammonium ion; IEA:Ensembl.
DR   GO; GO:0014074; P:response to purine-containing compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PURA_HUMAN              Reviewed;         322 AA.
AC   Q00577;
DE   RecName: Full=Transcriptional activator protein Pur-alpha;
DE   AltName: Full=Purine-rich single-stranded DNA-binding protein alpha;
GN   Name=PURA; Synonyms=PUR1;
DR   GO; GO:0003691; F:double-stranded telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032422; F:purine-rich negative regulatory element binding; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; IEA:Ensembl.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
//
ID   PURB_HUMAN              Reviewed;         312 AA.
AC   Q96QR8; A4D2L7;
DE   RecName: Full=Transcriptional activator protein Pur-beta;
DE   AltName: Full=Purine-rich element-binding protein B;
GN   Name=PURB;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045637; P:regulation of myeloid cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   PURG_HUMAN              Reviewed;         347 AA.
AC   Q9UJV8; Q8TE64;
DE   RecName: Full=Purine-rich element-binding protein gamma;
GN   Name=PURG;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   PUS10_HUMAN             Reviewed;         529 AA.
AC   Q3MIT2; Q5JPJ5; Q96MI8;
DE   RecName: Full=Putative tRNA pseudouridine synthase Pus10;
DE            EC=5.4.99.-;
DE   AltName: Full=Coiled-coil domain-containing protein 139;
DE   AltName: Full=tRNA pseudouridine 55 synthase;
DE            Short=Psi55 synthase;
DE   AltName: Full=tRNA pseudouridylate synthase;
DE   AltName: Full=tRNA-uridine isomerase;
GN   Name=PUS10; Synonyms=CCDC139, DOBI;
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   PUS3_HUMAN              Reviewed;         481 AA.
AC   Q9BZE2; B2RAM0; Q96D17; Q96J23; Q96NB4;
DE   RecName: Full=tRNA pseudouridine(38/39) synthase;
DE            EC=5.4.99.45;
DE   AltName: Full=tRNA pseudouridine synthase 3;
DE   AltName: Full=tRNA pseudouridylate synthase 3;
DE   AltName: Full=tRNA-uridine isomerase 3;
GN   Name=PUS3; ORFNames=FKSG32;
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0031119; P:tRNA pseudouridine synthesis; IEA:Ensembl.
//
ID   PUS7L_HUMAN             Reviewed;         701 AA.
AC   Q9H0K6; B3KUJ1; Q05CU0; Q6AHZ3; Q6NUP2;
DE   RecName: Full=Pseudouridylate synthase 7 homolog-like protein;
DE            EC=5.4.99.-;
GN   Name=PUS7L;
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   PUS7_HUMAN              Reviewed;         661 AA.
AC   Q96PZ0; Q75MG4; Q9NX19;
DE   RecName: Full=Pseudouridylate synthase 7 homolog;
DE            EC=5.4.99.-;
GN   Name=PUS7; Synonyms=KIAA1897;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   PUSL1_HUMAN             Reviewed;         303 AA.
AC   Q8N0Z8; B4DP76; Q5TA41;
DE   RecName: Full=tRNA pseudouridine synthase-like 1;
DE            EC=5.4.99.-;
DE   AltName: Full=tRNA pseudouridylate synthase-like 1;
DE   AltName: Full=tRNA-uridine isomerase-like 1;
GN   Name=PUSL1;
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   PVRIG_HUMAN             Reviewed;         326 AA.
AC   Q6DKI7; D6W5U9; Q9BVK3;
DE   RecName: Full=Transmembrane protein PVRIG;
DE   AltName: Full=Poliovirus receptor-related immunoglobulin domain-containing protein;
GN   Name=PVRIG; Synonyms=C7orf15;
//
ID   PVRL1_HUMAN             Reviewed;         517 AA.
AC   Q15223; O75465; Q2M3D3; Q9HBE6; Q9HBW2;
DE   RecName: Full=Nectin-1;
DE   AltName: Full=Herpes virus entry mediator C;
DE            Short=Herpesvirus entry mediator C;
DE            Short=HveC;
DE   AltName: Full=Herpesvirus Ig-like receptor;
DE            Short=HIgR;
DE   AltName: Full=Poliovirus receptor-related protein 1;
DE   AltName: CD_antigen=CD111;
DE   Flags: Precursor;
GN   Name=PVRL1; Synonyms=HVEC, PRR1;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:HGNC.
DR   GO; GO:0046790; F:virion binding; IEA:Ensembl.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0002934; P:desmosome organization; IEA:Ensembl.
DR   GO; GO:0070166; P:enamel mineralization; IEA:Ensembl.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; ISS:HGNC.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:HGNC.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006826; P:iron ion transport; IEA:Ensembl.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0051963; P:regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0046718; P:viral entry into host cell; NAS:UniProtKB.
//
ID   PVRL2_HUMAN             Reviewed;         538 AA.
AC   Q92692; A8K5L5; O75455; Q6IBI6; Q96J29;
DE   RecName: Full=Nectin-2;
DE   AltName: Full=Herpes virus entry mediator B;
DE            Short=Herpesvirus entry mediator B;
DE            Short=HveB;
DE   AltName: Full=Poliovirus receptor-related protein 2;
DE   AltName: CD_antigen=CD112;
DE   Flags: Precursor;
GN   Name=PVRL2; Synonyms=HVEB, PRR2;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0051856; ?:?; IDA:BHF-UCL.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0032990; P:cell part morphogenesis; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0044782; P:cilium organization; IEA:Ensembl.
DR   GO; GO:0046814; P:coreceptor-mediated virion attachment to host cell; IDA:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0051654; P:establishment of mitochondrion localization; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0002891; P:positive regulation of immunoglobulin mediated immune response; IMP:BHF-UCL.
DR   GO; GO:0033005; P:positive regulation of mast cell activation; IMP:BHF-UCL.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IMP:BHF-UCL.
DR   GO; GO:0002860; P:positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; IMP:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0030382; P:sperm mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; ISS:BHF-UCL.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
DR   GO; GO:0042271; P:susceptibility to natural killer cell mediated cytotoxicity; IMP:BHF-UCL.
DR   GO; GO:0060370; P:susceptibility to T cell mediated cytotoxicity; IDA:BHF-UCL.
//
ID   PVRL3_HUMAN             Reviewed;         549 AA.
AC   Q9NQS3; E9PFR0; Q6NVZ3; Q8NC05; Q8WVU4; Q9BVA9; Q9Y412;
DE   RecName: Full=Nectin-3;
DE   AltName: Full=CDw113;
DE   AltName: Full=Poliovirus receptor-related protein 3;
DE   AltName: CD_antigen=CD113;
DE   Flags: Precursor;
GN   Name=PVRL3; Synonyms=PRR3;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:HGNC.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:HGNC.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IEA:Ensembl.
//
ID   PVR_HUMAN               Reviewed;         417 AA.
AC   P15151; B4DTS9; P15152; Q15267; Q15268; Q96BJ1;
DE   RecName: Full=Poliovirus receptor;
DE   AltName: Full=Nectin-like protein 5;
DE            Short=NECL-5;
DE   AltName: CD_antigen=CD155;
DE   Flags: Precursor;
GN   Name=PVR; Synonyms=PVS;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0001618; F:virus receptor activity; IEA:Ensembl.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IMP:BHF-UCL.
DR   GO; GO:0002860; P:positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; IMP:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0042271; P:susceptibility to natural killer cell mediated cytotoxicity; IMP:BHF-UCL.
DR   GO; GO:0060370; P:susceptibility to T cell mediated cytotoxicity; IDA:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PWP1_HUMAN              Reviewed;         501 AA.
AC   Q13610; A8K3R6;
DE   RecName: Full=Periodic tryptophan protein 1 homolog;
DE   AltName: Full=Keratinocyte protein IEF SSP 9502;
GN   Name=PWP1;
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   PWP2A_HUMAN             Reviewed;         755 AA.
AC   Q96N64; G5EA07; Q2HJJ2; Q8IYR3; Q96PV3;
DE   RecName: Full=PWWP domain-containing protein 2A;
GN   Name=PWWP2A; Synonyms=KIAA1935, MST101;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PWP2B_HUMAN             Reviewed;         590 AA.
AC   Q6NUJ5; A6NM90; B5MDQ1; H9KV61; Q5SZI0; Q6ZQX5; Q96F43;
DE   RecName: Full=PWWP domain-containing protein 2B;
GN   Name=PWWP2B; Synonyms=PWWP2;
//
ID   PWP2_HUMAN              Reviewed;         919 AA.
AC   Q15269; B2RAG8; Q96A77;
DE   RecName: Full=Periodic tryptophan protein 2 homolog;
GN   Name=PWP2; Synonyms=PWP2H;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   PVRL4_HUMAN             Reviewed;         510 AA.
AC   Q96NY8; Q96K15;
DE   RecName: Full=Nectin-4;
DE   AltName: Full=Ig superfamily receptor LNIR;
DE   AltName: Full=Poliovirus receptor-related protein 4;
DE   Contains:
DE     RecName: Full=Processed poliovirus receptor-related protein 4;
DE   Flags: Precursor;
GN   Name=PVRL4; Synonyms=LNIR, PRR4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034332; P:adherens junction organization; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0045216; P:cell-cell junction organization; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   PX11A_HUMAN             Reviewed;         247 AA.
AC   O75192; B4DV88;
DE   RecName: Full=Peroxisomal membrane protein 11A;
DE            Short=HsPEX11p;
DE   AltName: Full=28 kDa peroxisomal integral membrane protein;
DE            Short=PMP28;
DE   AltName: Full=Peroxin-11A;
DE   AltName: Full=Peroxisomal biogenesis factor 11A;
DE   AltName: Full=Protein PEX11 homolog alpha;
DE            Short=PEX11-alpha;
GN   Name=PEX11A; Synonyms=PEX11;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0016559; P:peroxisome fission; IEA:InterPro.
DR   GO; GO:0016557; P:peroxisome membrane biogenesis; IEA:Ensembl.
DR   GO; GO:0007031; P:peroxisome organization; IMP:UniProtKB.
DR   GO; GO:0044375; P:regulation of peroxisome size; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PX11B_HUMAN             Reviewed;         259 AA.
AC   O96011; B3KN85; B4DXH9; Q96ET2;
DE   RecName: Full=Peroxisomal membrane protein 11B;
DE   AltName: Full=Peroxin-11B;
DE   AltName: Full=Peroxisomal biogenesis factor 11B;
DE   AltName: Full=Protein PEX11 homolog beta;
DE            Short=PEX11-beta;
GN   Name=PEX11B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IDA:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0044375; P:regulation of peroxisome size; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
//
ID   PX11C_HUMAN             Reviewed;         241 AA.
AC   Q96HA9; Q8NDM0;
DE   RecName: Full=Peroxisomal membrane protein 11C;
DE   AltName: Full=Peroxin-11C;
DE   AltName: Full=Peroxisomal biogenesis factor 11C;
DE   AltName: Full=Protein PEX11 homolog gamma;
DE            Short=PEX11-gamma;
GN   Name=PEX11G; Synonyms=PEX11C;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IDA:UniProtKB.
DR   GO; GO:0044375; P:regulation of peroxisome size; IDA:UniProtKB.
//
ID   PXDC2_HUMAN             Reviewed;         529 AA.
AC   Q6UX71; Q96E59; Q96PD9; Q96SU9;
DE   RecName: Full=Plexin domain-containing protein 2;
DE   AltName: Full=Tumor endothelial marker 7-related protein;
DE   Flags: Precursor;
GN   Name=PLXDC2; Synonyms=TEM7R; ORFNames=UNQ2514/PRO6003;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
//
ID   PXDC1_HUMAN             Reviewed;         231 AA.
AC   Q5TGL8; A8K0N3; Q6PGP0; Q86XB7;
DE   RecName: Full=PX domain-containing protein 1;
GN   Name=PXDC1; Synonyms=C6orf145;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
//
ID   PXDNL_HUMAN             Reviewed;        1463 AA.
AC   A1KZ92; B5ME43; B6CGZ3; H0YBM9; Q6ZMR2; Q96LH9;
DE   RecName: Full=Peroxidasin-like protein;
DE            EC=1.11.1.7;
DE   AltName: Full=Cardiac peroxidase;
DE   AltName: Full=Vascular peroxidase 2;
DE   AltName: Full=polysomal ribonuclease 1;
DE            Short=PRM1;
DE   Flags: Precursor;
GN   Name=PXDNL; Synonyms=VPO2;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; ISS:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; ISS:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:UniProtKB.
//
ID   PXDN_HUMAN              Reviewed;        1479 AA.
AC   Q92626; A8QM65; D6W4Y0; Q4KMG2;
DE   RecName: Full=Peroxidasin homolog;
DE            EC=1.11.1.7;
DE   AltName: Full=Melanoma-associated antigen MG50;
DE   AltName: Full=Vascular peroxidase 1;
DE   AltName: Full=p53-responsive gene 2 protein;
DE   Flags: Precursor;
GN   Name=PXDN; Synonyms=KIAA0230, MG50, PRG2, VPO, VPO1;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IDA:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005152; F:interleukin-1 receptor antagonist activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004601; F:peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; IDA:UniProtKB.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; NAS:GOC.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
//
ID   PXK_HUMAN               Reviewed;         578 AA.
AC   Q7Z7A4; Q3BCH4; Q3BCH5; Q3BCH6; Q3BDW1; Q45L83; Q59EX3; Q6PK17;
AC   Q6ZN39; Q96CA3; Q96R07; Q9NXB8;
DE   RecName: Full=PX domain-containing protein kinase-like protein;
DE   AltName: Full=Modulator of Na,K-ATPase;
DE            Short=MONaKA;
GN   Name=PXK;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:UniProtKB.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IMP:UniProtKB.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; IEA:Ensembl.
DR   GO; GO:0043271; P:negative regulation of ion transport; IEA:Ensembl.
DR   GO; GO:0050804; P:regulation of synaptic transmission; ISS:UniProtKB.
//
ID   PXMP2_HUMAN             Reviewed;         195 AA.
AC   Q9NR77;
DE   RecName: Full=Peroxisomal membrane protein 2;
DE   AltName: Full=22 kDa peroxisomal membrane protein;
GN   Name=PXMP2; Synonyms=PMP22;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   PXMP4_HUMAN             Reviewed;         212 AA.
AC   Q9Y6I8; A2A2I7; Q9H0T4;
DE   RecName: Full=Peroxisomal membrane protein 4;
DE   AltName: Full=24 kDa peroxisomal intrinsic membrane protein;
GN   Name=PXMP4; Synonyms=PMP24;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   PXT1_HUMAN              Reviewed;         134 AA.
AC   Q8NFP0; J3KR74;
DE   RecName: Full=Peroxisomal testis-specific protein 1;
DE   AltName: Full=Small testis-specific peroxisomal protein;
GN   Name=PXT1; Synonyms=STEPP;
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   PYC_HUMAN               Reviewed;        1178 AA.
AC   P11498; Q16705;
DE   RecName: Full=Pyruvate carboxylase, mitochondrial;
DE            EC=6.4.1.1;
DE   AltName: Full=Pyruvic carboxylase;
DE            Short=PCB;
DE   Flags: Precursor;
GN   Name=PC;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0009374; F:biotin binding; TAS:ProtInc.
DR   GO; GO:0004075; F:biotin carboxylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004736; F:pyruvate carboxylase activity; TAS:Reactome.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:Ensembl.
DR   GO; GO:0006090; P:pyruvate metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   PYDC1_HUMAN             Reviewed;          89 AA.
AC   Q8WXC3; B2R8L4; Q8NFP8;
DE   RecName: Full=Pyrin domain-containing protein 1;
DE   AltName: Full=PAAD-only protein 1;
DE   AltName: Full=Pyrin-only protein 1;
GN   Name=PYDC1; Synonyms=ASC2, ASCI, POP1, PYC1;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0045087; P:innate immune response; IDA:HGNC.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:HGNC.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:HGNC.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IDA:HGNC.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:HGNC.
//
ID   PYDC2_HUMAN             Reviewed;          97 AA.
AC   Q56P42;
DE   RecName: Full=Pyrin domain-containing protein 2;
DE   AltName: Full=Pyrin-only protein 2;
GN   Name=PYDC2; Synonyms=POP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   PYGB_HUMAN              Reviewed;         843 AA.
AC   P11216; Q96AK1; Q9NPX8;
DE   RecName: Full=Glycogen phosphorylase, brain form;
DE            EC=2.4.1.1;
GN   Name=PYGB;
DR   GO; GO:0008184; F:glycogen phosphorylase activity; NAS:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PYGL_HUMAN              Reviewed;         847 AA.
AC   P06737; A6NDQ4; B4DUB7; F5H816; O60567; O60752; O60913; Q501V9;
AC   Q641R5; Q96G82;
DE   RecName: Full=Glycogen phosphorylase, liver form;
DE            EC=2.4.1.1;
GN   Name=PYGL;
DR   GO; GO:0016208; F:AMP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0032052; F:bile acid binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0005536; F:glucose binding; NAS:UniProtKB.
DR   GO; GO:0008184; F:glycogen phosphorylase activity; IMP:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0002060; F:purine nucleobase binding; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019842; F:vitamin binding; IDA:UniProtKB.
DR   GO; GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PYGM_HUMAN              Reviewed;         842 AA.
AC   P11217; A0AVK1; A6NDY6;
DE   RecName: Full=Glycogen phosphorylase, muscle form;
DE            EC=2.4.1.1;
DE   AltName: Full=Myophosphorylase;
GN   Name=PYGM;
DR   GO; GO:0008184; F:glycogen phosphorylase activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005980; P:glycogen catabolic process; TAS:Reactome.
DR   GO; GO:0005977; P:glycogen metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PYGO1_HUMAN             Reviewed;         419 AA.
AC   Q9Y3Y4;
DE   RecName: Full=Pygopus homolog 1;
GN   Name=PYGO1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   PYGO2_HUMAN             Reviewed;         406 AA.
AC   Q9BRQ0; Q8WYZ4; Q96CY2;
DE   RecName: Full=Pygopus homolog 2;
GN   Name=PYGO2; ORFNames=PP7910;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0051569; P:regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0033599; P:regulation of mammary gland epithelial cell proliferation; IEA:Ensembl.
//
ID   PYR1_HUMAN              Reviewed;        2225 AA.
AC   P27708; D6W552; Q6P0Q0; Q96CK3;
DE   RecName: Full=CAD protein;
DE   Includes:
DE     RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase;
DE              EC=6.3.5.5;
DE   Includes:
DE     RecName: Full=Aspartate carbamoyltransferase;
DE              EC=2.1.3.2;
DE   Includes:
DE     RecName: Full=Dihydroorotase;
DE              EC=3.5.2.3;
GN   Name=CAD;
DR   GO; GO:0070335; F:aspartate binding; ISS:BHF-UCL.
DR   GO; GO:0004070; F:aspartate carbamoyltransferase activity; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; ISS:BHF-UCL.
DR   GO; GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; ISS:BHF-UCL.
DR   GO; GO:0004151; F:dihydroorotase activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0004672; F:protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0017144; P:drug metabolic process; ISS:BHF-UCL.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006543; P:glutamine catabolic process; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:BHF-UCL.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0051414; P:response to cortisol; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:Ensembl.
//
ID   PYRD1_HUMAN             Reviewed;         500 AA.
AC   Q8WU10; A6NKI6; Q9H6P1;
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1;
DE            EC=1.8.1.-;
GN   Name=PYROXD1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   PYRD2_HUMAN             Reviewed;         581 AA.
AC   Q8N2H3; D3DR61; Q5TAA9; Q9BRQ1;
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2;
DE            EC=1.-.-.-;
GN   Name=PYROXD2; Synonyms=C10orf33;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   PYRD_HUMAN              Reviewed;         395 AA.
AC   Q02127; A8K8C8; Q6P176;
DE   RecName: Full=Dihydroorotate dehydrogenase (quinone), mitochondrial;
DE            Short=DHOdehase;
DE            EC=1.3.5.2;
DE   AltName: Full=Dihydroorotate oxidase;
DE   Flags: Precursor;
GN   Name=DHODH;
DR   GuidetoPHARMACOLOGY; 2604; -.
DR   GO; GO:0004152; F:dihydroorotate dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0004158; F:dihydroorotate oxidase activity; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0010181; F:FMN binding; IEA:Ensembl.
DR   GO; GO:0048039; F:ubiquinone binding; IEA:Ensembl.
DR   GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
DR   GO; GO:0090140; P:regulation of mitochondrial fission; IEA:Ensembl.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PYRG1_HUMAN             Reviewed;         591 AA.
AC   P17812; D3DPW1; Q5VW67; Q96GK6;
DE   RecName: Full=CTP synthase 1;
DE            EC=6.3.4.2;
DE   AltName: Full=CTP synthetase 1;
DE   AltName: Full=UTP--ammonia ligase 1;
GN   Name=CTPS1; Synonyms=CTPS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003883; F:CTP synthase activity; IDA:UniProtKB.
DR   GO; GO:0044210; P:'de novo' CTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006241; P:CTP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PYRG2_HUMAN             Reviewed;         586 AA.
AC   Q9NRF8; B3KWM2; Q9BRI0; Q9H809; Q9H8K9;
DE   RecName: Full=CTP synthase 2;
DE            EC=6.3.4.2;
DE   AltName: Full=CTP synthetase 2;
DE   AltName: Full=UTP--ammonia ligase 2;
GN   Name=CTPS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003883; F:CTP synthase activity; EXP:Reactome.
DR   GO; GO:0044210; P:'de novo' CTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006220; P:pyrimidine nucleotide metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   PYY2_HUMAN              Reviewed;          33 AA.
AC   Q9NRI6;
DE   RecName: Full=Putative peptide YY-2;
DE            Short=Putative peptide YY2;
DE   Flags: Precursor;
GN   Name=PYY2;
//
ID   PYY3_HUMAN              Reviewed;          70 AA.
AC   Q5JQD4;
DE   RecName: Full=Putative peptide YY-3;
DE            Short=Putative peptide YY3;
DE   AltName: Full=PYY-III;
DE   Flags: Precursor;
GN   Name=PYY3;
//
ID   PYY_HUMAN               Reviewed;          97 AA.
AC   P10082; Q5U5Q6; Q6FGH8;
DE   RecName: Full=Peptide YY;
DE            Short=PYY;
DE   AltName: Full=PYY-I;
DE   AltName: Full=Peptide tyrosine tyrosine;
DE   Contains:
DE     RecName: Full=Peptide YY(3-36);
DE     AltName: Full=PYY-II;
DE   Flags: Precursor;
GN   Name=PYY;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007631; P:feeding behavior; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   PZP_HUMAN               Reviewed;        1482 AA.
AC   P20742; A6ND27; Q15273; Q2NKL2; Q7M4N7;
DE   RecName: Full=Pregnancy zone protein;
DE   AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6;
DE   Flags: Precursor;
GN   Name=PZP; Synonyms=CPAMD6;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007565; P:female pregnancy; TAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   PZRN3_HUMAN             Reviewed;        1066 AA.
AC   Q9UPQ7; A7MCZ6; Q8N2N7; Q96CC2; Q9NSQ2;
DE   RecName: Full=E3 ubiquitin-protein ligase PDZRN3;
DE            EC=6.3.2.-;
DE   AltName: Full=Ligand of Numb protein X 3;
DE   AltName: Full=PDZ domain-containing RING finger protein 3;
DE   AltName: Full=Semaphorin cytoplasmic domain-associated protein 3;
DE            Short=Protein SEMACAP3;
GN   Name=PDZRN3; Synonyms=KIAA1095, LNX3, SEMCAP3;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   PZRN4_HUMAN             Reviewed;        1036 AA.
AC   Q6ZMN7; Q52LY3; Q52LY4; Q6N052; Q8IUU1; Q9NTP7;
DE   RecName: Full=PDZ domain-containing RING finger protein 4;
DE   AltName: Full=Ligand of Numb protein X 4;
DE   AltName: Full=SEMACAP3-like protein;
GN   Name=PDZRN4; Synonyms=LNX4, SEMCAP3L;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   P_HUMAN                 Reviewed;         838 AA.
AC   Q04671; Q15211; Q15212; Q96EN1; Q9UMI5;
DE   RecName: Full=P protein;
DE   AltName: Full=Melanocyte-specific transporter protein;
DE   AltName: Full=Pink-eyed dilution protein homolog;
GN   Name=OCA2; Synonyms=D15S12, P;
DR   GO; GO:0005302; F:L-tyrosine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006726; P:eye pigment biosynthetic process; TAS:ProtInc.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0015828; P:tyrosine transport; TAS:GOC.
//
ID   QCR10_HUMAN             Reviewed;          56 AA.
AC   O14957; B2R542; D6W5Z4; Q9UEA3; Q9UPK4;
DE   RecName: Full=Cytochrome b-c1 complex subunit 10;
DE   AltName: Full=Complex III subunit 10;
DE   AltName: Full=Complex III subunit XI;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex 6.4 kDa protein;
GN   Name=UQCR11; Synonyms=UQCR;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   QCR1_HUMAN              Reviewed;         480 AA.
AC   P31930; B2R7R8; Q96DD2;
DE   RecName: Full=Cytochrome b-c1 complex subunit 1, mitochondrial;
DE   AltName: Full=Complex III subunit 1;
DE   AltName: Full=Core protein I;
DE   AltName: Full=Ubiquinol-cytochrome-c reductase complex core protein 1;
DE   Flags: Precursor;
GN   Name=UQCRC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; TAS:ProtInc.
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:ProtInc.
DR   GO; GO:0006119; P:oxidative phosphorylation; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0043279; P:response to alkaloid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   QCR2_HUMAN              Reviewed;         453 AA.
AC   P22695; B3KSN4; Q9BQ05;
DE   RecName: Full=Cytochrome b-c1 complex subunit 2, mitochondrial;
DE   AltName: Full=Complex III subunit 2;
DE   AltName: Full=Core protein II;
DE   AltName: Full=Ubiquinol-cytochrome-c reductase complex core protein 2;
DE   Flags: Precursor;
GN   Name=UQCRC2;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006119; P:oxidative phosphorylation; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   QCR6_HUMAN              Reviewed;          91 AA.
AC   P07919; B2R4V9; D3DQ18; Q5TDF6; Q6LDB8; Q9BQ91;
DE   RecName: Full=Cytochrome b-c1 complex subunit 6, mitochondrial;
DE   AltName: Full=Complex III subunit 6;
DE   AltName: Full=Complex III subunit VIII;
DE   AltName: Full=Cytochrome c1 non-heme 11 kDa protein;
DE   AltName: Full=Mitochondrial hinge protein;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex 11 kDa protein;
DE   Flags: Precursor;
GN   Name=UQCRH;
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; TAS:ProtInc.
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:ProtInc.
DR   GO; GO:0006119; P:oxidative phosphorylation; TAS:ProtInc.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   QCR7_HUMAN              Reviewed;         111 AA.
AC   P14927; E5RJU0; Q6FGD1;
DE   RecName: Full=Cytochrome b-c1 complex subunit 7;
DE   AltName: Full=Complex III subunit 7;
DE   AltName: Full=Complex III subunit VII;
DE   AltName: Full=QP-C;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex 14 kDa protein;
GN   Name=UQCRB; Synonyms=UQBP;
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:ProtInc.
DR   GO; GO:0006119; P:oxidative phosphorylation; TAS:ProtInc.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   QCR9_HUMAN              Reviewed;          63 AA.
AC   Q9UDW1; B5MCM5; Q9T2V6;
DE   RecName: Full=Cytochrome b-c1 complex subunit 9;
DE   AltName: Full=Complex III subunit 9;
DE   AltName: Full=Complex III subunit X;
DE   AltName: Full=Cytochrome c1 non-heme 7 kDa protein;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex 7.2 kDa protein;
GN   Name=UQCR10; Synonyms=UCRC; ORFNames=HSPC119;
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; NAS:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   QCR8_HUMAN              Reviewed;          82 AA.
AC   O14949; Q5FVE2; Q9BV88; Q9T2V7;
DE   RecName: Full=Cytochrome b-c1 complex subunit 8;
DE   AltName: Full=Complex III subunit 8;
DE   AltName: Full=Complex III subunit VIII;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex 9.5 kDa protein;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C;
GN   Name=UQCRQ;
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0021548; P:pons development; IEA:Ensembl.
DR   GO; GO:0021860; P:pyramidal neuron development; IEA:Ensembl.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021539; P:subthalamus development; IEA:Ensembl.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
//
ID   QIL1_HUMAN              Reviewed;         118 AA.
AC   Q5XKP0; Q86YE5;
DE   RecName: Full=Protein QIL1;
DE   AltName: Full=Protein P117;
GN   Name=QIL1; Synonyms=C19orf70;
//
ID   QKI_HUMAN               Reviewed;         341 AA.
AC   Q96PU8; Q2I375; Q5MJQ1; Q969L9; Q96EJ3; Q96KA3; Q96PU6; Q96PU7;
AC   Q9P0X6; Q9P0X7; Q9P0X8; Q9P0X9; Q9P0Y0; Q9P0Y1;
DE   RecName: Full=Protein quaking;
DE            Short=Hqk;
DE            Short=HqkI;
GN   Name=QKI; Synonyms=HKQ;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042759; P:long-chain fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   QORL1_HUMAN             Reviewed;         349 AA.
AC   O95825; B2RDX1; Q96DY0; Q9NVY7;
DE   RecName: Full=Quinone oxidoreductase-like protein 1;
DE            EC=1.-.-.-;
DE   AltName: Full=Protein 4P11;
DE   AltName: Full=Quinone oxidoreductase homolog 1;
DE            Short=QOH-1;
DE   AltName: Full=Zeta-crystallin homolog;
GN   Name=CRYZL1; Synonyms=4P11;
DR   GO; GO:0050661; F:NADP binding; NAS:UniProtKB.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:1901661; P:quinone metabolic process; NAS:UniProtKB.
//
ID   QORX_HUMAN              Reviewed;         332 AA.
AC   Q53FA7; D6W533; O14679; O14685; Q38G78; Q6JLE7; Q9BWB8;
DE   RecName: Full=Quinone oxidoreductase PIG3;
DE            EC=1.-.-.-;
DE   AltName: Full=Tumor protein p53-inducible protein 3;
DE   AltName: Full=p53-induced gene 3 protein;
GN   Name=TP53I3; Synonyms=PIG3;
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0048038; F:quinone binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006739; P:NADP metabolic process; IDA:UniProtKB.
//
ID   QOR_HUMAN               Reviewed;         329 AA.
AC   Q08257; A6NN60; D3DQ76; Q53FT0; Q59EU7; Q5HYE7; Q6NSK9;
DE   RecName: Full=Quinone oxidoreductase;
DE            EC=1.6.5.5;
DE   AltName: Full=NADPH:quinone reductase;
DE   AltName: Full=Zeta-crystallin;
GN   Name=CRYZ;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0070402; F:NADPH binding; IDA:UniProtKB.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
DR   GO; GO:0042178; P:xenobiotic catabolic process; IDA:UniProtKB.
//
ID   QPCTL_HUMAN             Reviewed;         382 AA.
AC   Q9NXS2; Q53HE4; Q96F74;
DE   RecName: Full=Glutaminyl-peptide cyclotransferase-like protein;
DE            EC=2.3.2.5;
DE   AltName: Full=Golgi-resident glutaminyl-peptide cyclotransferase;
DE   AltName: Full=isoQC;
DE            Short=gQC;
GN   Name=QPCTL;
DR   GO; GO:0016603; F:glutaminyl-peptide cyclotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0017186; P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; IDA:UniProtKB.
//
ID   QPCT_HUMAN              Reviewed;         361 AA.
AC   Q16769; Q16770; Q3KRG6; Q53TR4;
DE   RecName: Full=Glutaminyl-peptide cyclotransferase;
DE            EC=2.3.2.5;
DE   AltName: Full=Glutaminyl cyclase;
DE            Short=QC;
DE            Short=sQC;
DE   AltName: Full=Glutaminyl-tRNA cyclotransferase;
DE   AltName: Full=Glutamyl cyclase;
DE            Short=EC;
DE   Flags: Precursor;
GN   Name=QPCT;
DR   GO; GO:0016603; F:glutaminyl-peptide cyclotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0017186; P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase; IDA:UniProtKB.
//
ID   QRFPR_HUMAN             Reviewed;         431 AA.
AC   Q96P65;
DE   RecName: Full=Pyroglutamylated RFamide peptide receptor;
DE   AltName: Full=AQ27;
DE   AltName: Full=G-protein coupled receptor 103;
DE   AltName: Full=Orexigenic neuropeptide QRFP receptor;
DE   AltName: Full=SP9155;
GN   Name=QRFPR; Synonyms=GPR103;
DR   GuidetoPHARMACOLOGY; 333; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IDA:UniProtKB.
DR   GO; GO:0004983; F:neuropeptide Y receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
//
ID   QRIC1_HUMAN             Reviewed;         776 AA.
AC   Q2TAL8; Q4G0F7; Q7L621; Q8TEA5;
DE   RecName: Full=Glutamine-rich protein 1;
GN   Name=QRICH1;
//
ID   QRIC2_HUMAN             Reviewed;        1663 AA.
AC   Q9H0J4; A2RRE1; Q96LM3;
DE   RecName: Full=Glutamine-rich protein 2;
GN   Name=QRICH2;
//
ID   QSER1_HUMAN             Reviewed;        1735 AA.
AC   Q2KHR3; Q6ZU30; Q6ZUR5;
DE   RecName: Full=Glutamine and serine-rich protein 1;
GN   Name=QSER1;
//
ID   QSOX1_HUMAN             Reviewed;         747 AA.
AC   O00391; Q59G29; Q5T2X0; Q8TDL6; Q8WVP4;
DE   RecName: Full=Sulfhydryl oxidase 1;
DE            Short=hQSOX;
DE            EC=1.8.3.2;
DE   AltName: Full=Quiescin Q6;
DE   Flags: Precursor;
GN   Name=QSOX1; Synonyms=QSCN6; ORFNames=UNQ2520/PRO6013;
DR   GO; GO:0016971; F:flavin-linked sulfhydryl oxidase activity; IDA:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IDA:GOC.
//
ID   QSOX2_HUMAN             Reviewed;         698 AA.
AC   Q6ZRP7; A2CEE0; A6NLB0; Q5TB37; Q7Z7B6; Q86VV7; Q8N3G2;
DE   RecName: Full=Sulfhydryl oxidase 2;
DE            EC=1.8.3.2;
DE   AltName: Full=Neuroblastoma-derived sulfhydryl oxidase;
DE   AltName: Full=Quiescin Q6-like protein 1;
DE   Flags: Precursor;
GN   Name=QSOX2; Synonyms=QSCN6L1, SOXN;
DR   GO; GO:0016972; F:thiol oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   QTRD1_HUMAN             Reviewed;         415 AA.
AC   Q9H974; A6NGE9; B7Z472; B7Z5R2; J3KR78; Q6IA59;
DE   RecName: Full=Queuine tRNA-ribosyltransferase subunit QTRTD1;
DE            EC=2.4.2.29;
DE   AltName: Full=Queuine tRNA-ribosyltransferase domain-containing protein 1;
GN   Name=QTRTD1;
DR   GO; GO:0008479; F:queuine tRNA-ribosyltransferase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008616; P:queuosine biosynthetic process; ISS:UniProtKB.
//
ID   R10B1_HUMAN             Reviewed;         870 AA.
AC   P0C881; A6NMW7; Q86ST9; Q8NE68;
DE   RecName: Full=Radial spoke head 10 homolog B;
GN   Name=RSPH10B;
//
ID   R10B2_HUMAN             Reviewed;         870 AA.
AC   B2RC85; A6NMW7; B2RXI4; B2RXJ0; Q86ST9; Q8NE68;
DE   RecName: Full=Radial spoke head 10 homolog B2;
GN   Name=RSPH10B2;
//
ID   R113A_HUMAN             Reviewed;         343 AA.
AC   O15541;
DE   RecName: Full=RING finger protein 113A;
DE   AltName: Full=Zinc finger protein 183;
GN   Name=RNF113A; Synonyms=RNF113, ZNF183;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   R114L_HUMAN             Reviewed;         266 AA.
AC   Q7Z4M0;
DE   RecName: Full=Meiotic recombination protein REC114-like;
GN   Name=C15orf60;
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   R113B_HUMAN             Reviewed;         322 AA.
AC   Q8IZP6; Q8WWF9; Q96QY9;
DE   RecName: Full=RING finger protein 113B;
DE   AltName: Full=Zinc finger protein 183-like 1;
GN   Name=RNF113B; Synonyms=RNF161, ZNF183L1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   R13P3_HUMAN             Reviewed;         102 AA.
AC   Q6NVV1;
DE   RecName: Full=Putative 60S ribosomal protein L13a protein RPL13AP3;
DE   AltName: Full=60S ribosomal protein L13a pseudogene 3;
GN   Name=RPL13AP3;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   R144A_HUMAN             Reviewed;         292 AA.
AC   P50876; D6W4Y6; Q585H5;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase RNF144A;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 144A;
DE   AltName: Full=UbcM4-interacting protein 4;
DE   AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 4;
GN   Name=RNF144A; Synonyms=KIAA0161, RNF144, UBCE7IP4;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   R144B_HUMAN             Reviewed;         303 AA.
AC   Q7Z419; B3KUA8; Q5TB85; Q6P4Q0; Q8N3R7; Q9BX38;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF144B;
DE            EC=6.3.2.-;
DE   AltName: Full=IBR domain-containing protein 2;
DE   AltName: Full=RING finger protein 144B;
DE   AltName: Full=p53-inducible RING finger protein;
GN   Name=RNF144B; Synonyms=IBRDC2, P53RFP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   R216L_HUMAN             Reviewed;          42 AA.
AC   Q6NUR6; B7Z8S6;
DE   RecName: Full=Putative protein RNF216-like;
GN   Name=RNF216P1; Synonyms=RNF216L;
//
ID   R39L5_HUMAN             Reviewed;          51 AA.
AC   Q59GN2;
DE   RecName: Full=Putative 60S ribosomal protein L39-like 5;
DE   AltName: Full=60S ribosomal protein L39 pseudogene 5;
GN   Name=RPL39P5;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   R3HC1_HUMAN             Reviewed;         480 AA.
AC   Q9Y3T6; B7ZLI1;
DE   RecName: Full=R3H and coiled-coil domain-containing protein 1;
GN   Name=R3HCC1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   R3HCL_HUMAN             Reviewed;         792 AA.
AC   Q7Z5L2; O60598; Q5W0B4; Q5W0B5; Q86VT9; Q8N9H0;
DE   RecName: Full=Coiled-coil domain-containing protein R3HCC1L;
DE   AltName: Full=Growth inhibition and differentiation-related protein 88;
DE   AltName: Full=Putative mitochondrial space protein 32.1;
DE   AltName: Full=R3H and coiled-coil domain-containing protein 1-like;
GN   Name=R3HCC1L; Synonyms=C10orf28, GIDRP88;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   R3GEF_HUMAN             Reviewed;         382 AA.
AC   Q8TBN0; Q86V32; Q9P1Q8;
DE   RecName: Full=Guanine nucleotide exchange factor for Rab-3A;
DE   AltName: Full=Rab-3A-interacting-like protein 1;
DE            Short=Rab3A-interacting-like protein 1;
DE   AltName: Full=Rabin3-like 1;
GN   Name=RAB3IL1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   R3HD1_HUMAN             Reviewed;        1099 AA.
AC   Q15032; A8K1V0; B3KXQ9; E9PBB4; E9PG42; Q8IW32;
DE   RecName: Full=R3H domain-containing protein 1;
GN   Name=R3HDM1; Synonyms=KIAA0029, R3HDM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   R3HD2_HUMAN             Reviewed;         976 AA.
AC   Q9Y2K5; Q2M1T9; Q3ZCT5;
DE   RecName: Full=R3H domain-containing protein 2;
GN   Name=R3HDM2; Synonyms=KIAA1002;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   R3HD4_HUMAN             Reviewed;         268 AA.
AC   Q96D70;
DE   RecName: Full=R3H domain-containing protein 4;
GN   Name=R3HDM4; Synonyms=C19orf22;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   R4RL1_HUMAN             Reviewed;         441 AA.
AC   Q86UN2; A1A5E3; Q8ND46;
DE   RecName: Full=Reticulon-4 receptor-like 1;
DE   AltName: Full=Nogo receptor-like 2;
DE   AltName: Full=Nogo-66 receptor homolog 2;
DE   AltName: Full=Nogo-66 receptor-related protein 3;
DE            Short=NgR3;
DE   Flags: Precursor;
GN   Name=RTN4RL1; Synonyms=NGRH2, NGRL2;
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0031103; P:axon regeneration; TAS:UniProtKB.
//
ID   R51A1_HUMAN             Reviewed;         352 AA.
AC   Q96B01; A8K7D3; O43403; Q7Z779;
DE   RecName: Full=RAD51-associated protein 1;
DE   AltName: Full=RAD51-interacting protein;
GN   Name=RAD51AP1; Synonyms=PIR51;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; NAS:UniProtKB.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.
//
ID   R4RL2_HUMAN             Reviewed;         420 AA.
AC   Q86UN3; Q0GGW3; Q17RL9; Q6X813;
DE   RecName: Full=Reticulon-4 receptor-like 2;
DE   AltName: Full=Nogo receptor-like 3;
DE   AltName: Full=Nogo-66 receptor homolog 1;
DE   AltName: Full=Nogo-66 receptor-related protein 2;
DE            Short=NgR2;
DE   Flags: Precursor;
GN   Name=RTN4RL2; Synonyms=NGRH1, NGRL3;
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0031103; P:axon regeneration; TAS:UniProtKB.
//
ID   R51A2_HUMAN             Reviewed;        1159 AA.
AC   Q09MP3;
DE   RecName: Full=RAD51-associated protein 2;
GN   Name=RAD51AP2;
//
ID   R7BP_HUMAN              Reviewed;         257 AA.
AC   Q6MZT1; B7Z3X1;
DE   RecName: Full=Regulator of G-protein signaling 7-binding protein;
DE   AltName: Full=R7 family-binding protein;
GN   Name=RGS7BP; Synonyms=R7BP;
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
//
ID   R9BP_HUMAN              Reviewed;         235 AA.
AC   Q6ZS82; Q6ZVJ6;
DE   RecName: Full=Regulator of G-protein signaling 9-binding protein;
DE   AltName: Full=RGS9-anchoring protein;
GN   Name=RGS9BP; Synonyms=R9AP;
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
//
ID   RA1L2_HUMAN             Reviewed;         320 AA.
AC   Q32P51; Q5TBS2;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A1-like 2;
DE            Short=hnRNP A1-like 2;
DE   AltName: Full=hnRNP core protein A1-like 2;
GN   Name=HNRNPA1L2; Synonyms=HNRNPA1L;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RA51B_HUMAN             Reviewed;         384 AA.
AC   O15315; O60914; O75210; Q3Y4F8; Q6FHX8; Q86SY3; Q86SY4; Q86TR0;
AC   Q86U92; Q86U93; Q86U94; Q8N6H4; Q9UPL5;
DE   RecName: Full=DNA repair protein RAD51 homolog 2;
DE            Short=R51H2;
DE   AltName: Full=RAD51 homolog B;
DE            Short=Rad51B;
DE   AltName: Full=RAD51-like protein 1;
GN   Name=RAD51B; Synonyms=RAD51L1, REC2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
//
ID   RA51C_HUMAN             Reviewed;         376 AA.
AC   O43502; O43503; Q3B783;
DE   RecName: Full=DNA repair protein RAD51 homolog 3;
DE            Short=R51H3;
DE   AltName: Full=RAD51 homolog C;
DE   AltName: Full=RAD51-like protein 2;
GN   Name=RAD51C; Synonyms=RAD51L2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008821; F:crossover junction endodeoxyribonuclease activity; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IMP:GOC.
DR   GO; GO:0006310; P:DNA recombination; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007066; P:female meiosis sister chromatid cohesion; IEA:Ensembl.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IEA:Ensembl.
DR   GO; GO:0007062; P:sister chromatid cohesion; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   RA51D_HUMAN             Reviewed;         328 AA.
AC   O75771; B4DJU7; E1P637; O43537; O60355; O75196; O75847; O75848;
AC   O76073; O76085; O94908; Q9UFU5;
DE   RecName: Full=DNA repair protein RAD51 homolog 4;
DE   AltName: Full=R51H3;
DE   AltName: Full=RAD51 homolog D;
DE   AltName: Full=RAD51-like protein 3;
DE   AltName: Full=TRAD;
GN   Name=RAD51D; Synonyms=RAD51L3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0042148; P:strand invasion; IDA:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
//
ID   RA54B_HUMAN             Reviewed;         910 AA.
AC   Q9Y620; F6WBS8;
DE   RecName: Full=DNA repair and recombination protein RAD54B;
DE            EC=3.6.4.-;
DE   AltName: Full=RAD54 homolog B;
GN   Name=RAD54B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0015616; F:DNA translocase activity; IDA:MGI.
DR   GO; GO:0003724; F:RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IDA:MGI.
DR   GO; GO:0006312; P:mitotic recombination; TAS:ProtInc.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
//
ID   RAB10_HUMAN             Reviewed;         200 AA.
AC   P61026; D6W538; O88386; Q6IA52; Q9D7X6; Q9H0T3;
DE   RecName: Full=Ras-related protein Rab-10;
GN   Name=RAB10;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; EXP:Reactome.
DR   GO; GO:0031489; F:myosin V binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0061467; P:basolateral protein localization; ISS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0045200; P:establishment of neuroblast polarity; ISS:UniProtKB.
DR   GO; GO:0097051; P:establishment of protein localization to endoplasmic reticulum membrane; IMP:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; EXP:GOC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0030859; P:polarized epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   RAB12_HUMAN             Reviewed;         244 AA.
AC   Q6IQ22; A6NEF5; Q4KMQ3;
DE   RecName: Full=Ras-related protein Rab-12;
GN   Name=RAB12;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044257; P:cellular protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB15_HUMAN             Reviewed;         212 AA.
AC   P59190; G5EMR7; Q86TX7; Q8IW89;
DE   RecName: Full=Ras-related protein Rab-15;
GN   Name=RAB15;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB18_HUMAN             Reviewed;         206 AA.
AC   Q9NP72; B3KMC7; B7Z333; D3DRW1; Q53FX8; Q56UN9; Q6FIH1;
DE   RecName: Full=Ras-related protein Rab-18;
DE   Flags: Precursor;
GN   Name=RAB18;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0001654; P:eye development; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
//
ID   RAB19_HUMAN             Reviewed;         217 AA.
AC   A4D1S5; A4D1S6; B2RTS6; B5MDR2; Q9UL27;
DE   RecName: Full=Ras-related protein Rab-19;
GN   Name=RAB19; Synonyms=RAB19B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB14_HUMAN             Reviewed;         215 AA.
AC   P61106; B3KR31; P35287; Q5JVD4; Q6Q7K5; Q969L0; Q9UI11;
DE   RecName: Full=Ras-related protein Rab-14;
GN   Name=RAB14;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; IDA:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0046907; P:intracellular transport; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
//
ID   RAB13_HUMAN             Reviewed;         203 AA.
AC   P51153; A8K6B5; D3DV67; Q5U0A6; Q6GPG6; Q96GU4;
DE   RecName: Full=Ras-related protein Rab-13;
DE   AltName: Full=Cell growth-inhibiting gene 4 protein;
DE   Flags: Precursor;
GN   Name=RAB13; ORFNames=GIG4;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0097368; P:establishment of Sertoli cell barrier; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; EXP:GOC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0010737; P:protein kinase A signaling; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0070830; P:tight junction assembly; IMP:UniProtKB.
DR   GO; GO:0044795; P:trans-Golgi network to recycling endosome transport; ISS:UniProtKB.
//
ID   RAB1A_HUMAN             Reviewed;         205 AA.
AC   P62820; P11476; Q6FIE7; Q96N61; Q9Y3T2;
DE   RecName: Full=Ras-related protein Rab-1A;
DE   AltName: Full=YPT1-related protein;
GN   Name=RAB1A; Synonyms=RAB1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:UniProtKB.
DR   GO; GO:0030252; P:growth hormone secretion; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0072606; P:interleukin-8 secretion; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0047496; P:vesicle transport along microtubule; IMP:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   RAB1B_HUMAN             Reviewed;         201 AA.
AC   Q9H0U4; A8K7S1;
DE   RecName: Full=Ras-related protein Rab-1B;
GN   Name=RAB1B;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB17_HUMAN             Reviewed;         212 AA.
AC   Q9H0T7; Q53QV6; Q6IA73; Q9BVU1; Q9H9U9;
DE   RecName: Full=Ras-related protein Rab-17;
GN   Name=RAB17;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0032456; P:endocytic recycling; ISS:UniProtKB.
DR   GO; GO:0032401; P:establishment of melanosome localization; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0002415; P:immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; ISS:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0050773; P:regulation of dendrite development; ISS:UniProtKB.
DR   GO; GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0045056; P:transcytosis; ISS:UniProtKB.
//
ID   RAB1C_HUMAN             Reviewed;         201 AA.
AC   Q92928;
DE   RecName: Full=Putative Ras-related protein Rab-1C;
DE            Short=hRab1c;
GN   Name=RAB1C;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB20_HUMAN             Reviewed;         234 AA.
AC   Q9NX57; Q5T9X5; Q9NX49;
DE   RecName: Full=Ras-related protein Rab-20;
GN   Name=RAB20;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0090383; P:phagosome acidification; IMP:UniProtKB.
DR   GO; GO:0090385; P:phagosome-lysosome fusion; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB21_HUMAN             Reviewed;         225 AA.
AC   Q9UL25; Q14466; Q569H3;
DE   RecName: Full=Ras-related protein Rab-21;
DE   Flags: Precursor;
GN   Name=RAB21; Synonyms=KIAA0118;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB24_HUMAN             Reviewed;         203 AA.
AC   Q969Q5; Q7Z4Z7;
DE   RecName: Full=Ras-related protein Rab-24;
GN   Name=RAB24;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB23_HUMAN             Reviewed;         237 AA.
AC   Q9ULC3; B2R9I5; Q68DJ6; Q8NI06; Q9P023;
DE   RecName: Full=Ras-related protein Rab-23;
DE   Flags: Precursor;
GN   Name=RAB23; ORFNames=HSPC137;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; IMP:UniProtKB.
DR   GO; GO:0097094; P:craniofacial suture morphogenesis; IMP:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0042992; P:negative regulation of transcription factor import into nucleus; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0021513; P:spinal cord dorsal/ventral patterning; IEA:Ensembl.
//
ID   RAB25_HUMAN             Reviewed;         213 AA.
AC   P57735; Q5VYA2; Q8NG24; Q96GB1; Q9BT12;
DE   RecName: Full=Ras-related protein Rab-25;
DE   AltName: Full=CATX-8;
DE   Flags: Precursor;
GN   Name=RAB25; Synonyms=CATX8;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0031268; P:pseudopodium organization; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB26_HUMAN             Reviewed;         256 AA.
AC   Q9ULW5; Q3L6K5; Q6NXS7;
DE   RecName: Full=Ras-related protein Rab-26;
GN   Name=RAB26;
DR   GO; GO:0019002; F:GMP binding; IMP:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IMP:UniProtKB.
DR   GO; GO:0035272; P:exocrine system development; IMP:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.
DR   GO; GO:0045055; P:regulated secretory pathway; IMP:UniProtKB.
DR   GO; GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB28_HUMAN             Reviewed;         221 AA.
AC   P51157; G8JLC5; Q8IYR8; Q8NI05;
DE   RecName: Full=Ras-related protein Rab-28;
DE   Flags: Precursor;
GN   Name=RAB28;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB2A_HUMAN             Reviewed;         212 AA.
AC   P61019; B2R5W8; B4DMQ5; P08886;
DE   RecName: Full=Ras-related protein Rab-2A;
GN   Name=RAB2A; Synonyms=RAB2;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB2B_HUMAN             Reviewed;         216 AA.
AC   Q8WUD1; B2RD03; D3DS24;
DE   RecName: Full=Ras-related protein Rab-2B;
GN   Name=RAB2B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   RAB30_HUMAN             Reviewed;         203 AA.
AC   Q15771; Q6FGK1; Q96CI8;
DE   RecName: Full=Ras-related protein Rab-30;
DE   Flags: Precursor;
GN   Name=RAB30;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB32_HUMAN             Reviewed;         225 AA.
AC   Q13637;
DE   RecName: Full=Ras-related protein Rab-32;
GN   Name=RAB32;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0090382; P:phagosome maturation; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB31_HUMAN             Reviewed;         194 AA.
AC   Q13636; B2RBT7; Q15770; Q9HC00;
DE   RecName: Full=Ras-related protein Rab-31;
DE   AltName: Full=Ras-related protein Rab-22B;
GN   Name=RAB31; Synonyms=RAB22B;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:UniProtKB.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0090382; P:phagosome maturation; IMP:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IMP:UniProtKB.
DR   GO; GO:0045055; P:regulated secretory pathway; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB34_HUMAN             Reviewed;         259 AA.
AC   Q9BZG1; B4E3A0; E9PEJ9; Q5BJE6; Q8NCJ8; Q96AR4;
DE   RecName: Full=Ras-related protein Rab-34;
DE   AltName: Full=Ras-related protein Rab-39;
DE   AltName: Full=Ras-related protein Rah;
GN   Name=RAB34; Synonyms=RAB39, RAH;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProt.
DR   GO; GO:0032418; P:lysosome localization; IDA:UniProt.
DR   GO; GO:0090382; P:phagosome maturation; IMP:UniProtKB.
DR   GO; GO:0090385; P:phagosome-lysosome fusion; IMP:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProt.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB35_HUMAN             Reviewed;         201 AA.
AC   Q15286; B2R6E0; B4E390;
DE   RecName: Full=Ras-related protein Rab-35;
DE   AltName: Full=GTP-binding protein RAY;
DE   AltName: Full=Ras-related protein Rab-1C;
GN   Name=RAB35; Synonyms=RAB1C, RAY;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:0036010; P:protein localization to endosome; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB36_HUMAN             Reviewed;         333 AA.
AC   O95755; Q2M390; Q7Z4A9; Q9UHP5;
DE   RecName: Full=Ras-related protein Rab-36;
GN   Name=RAB36;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB37_HUMAN             Reviewed;         223 AA.
AC   Q96AX2; A8MXF5; A8MYT0; Q8IWA7;
DE   RecName: Full=Ras-related protein Rab-37;
DE   Flags: Precursor;
GN   Name=RAB37;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB38_HUMAN             Reviewed;         211 AA.
AC   P57729; Q53XK7;
DE   RecName: Full=Ras-related protein Rab-38;
DE   AltName: Full=Melanoma antigen NY-MEL-1;
GN   Name=RAB38;
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0090383; P:phagosome acidification; IMP:UniProtKB.
DR   GO; GO:0060155; P:platelet dense granule organization; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
//
ID   RAB3A_HUMAN             Reviewed;         220 AA.
AC   P20336; A8K0J4; Q9NYE1;
DE   RecName: Full=Ras-related protein Rab-3A;
GN   Name=RAB3A;
DR   GO; GO:0001671; F:ATPase activator activity; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; IMP:GOC.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0048790; P:maintenance of presynaptic active zone structure; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0031630; P:regulation of synaptic vesicle fusion to presynaptic membrane; IEA:Ensembl.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0050975; P:sensory perception of touch; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
DR   GO; GO:0016188; P:synaptic vesicle maturation; IEA:Ensembl.
//
ID   RAB3B_HUMAN             Reviewed;         219 AA.
AC   P20337; Q5VUL2; Q9BSI1;
DE   RecName: Full=Ras-related protein Rab-3B;
GN   Name=RAB3B;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProt.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0018125; P:peptidyl-cysteine methylation; IEA:Ensembl.
DR   GO; GO:0051586; P:positive regulation of dopamine uptake involved in synaptic transmission; IDA:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0097494; P:regulation of vesicle size; IDA:UniProt.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB3C_HUMAN             Reviewed;         227 AA.
AC   Q96E17;
DE   RecName: Full=Ras-related protein Rab-3C;
GN   Name=RAB3C;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB3D_HUMAN             Reviewed;         219 AA.
AC   O95716;
DE   RecName: Full=Ras-related protein Rab-3D;
GN   Name=RAB3D; Synonyms=GOV, RAB16;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0018125; P:peptidyl-cysteine methylation; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB3I_HUMAN             Reviewed;         476 AA.
AC   Q96QF0; B7WPJ6; Q6PCE4; Q96A24; Q96QE6; Q96QE7; Q96QE8; Q96QE9;
AC   Q96QF1; Q9H673;
DE   RecName: Full=Rab-3A-interacting protein;
DE            Short=Rab3A-interacting protein;
DE   AltName: Full=Rabin-3;
DE   AltName: Full=SSX2-interacting protein;
GN   Name=RAB3IP; Synonyms=RABIN8;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; TAS:BHF-UCL.
DR   GO; GO:0033365; P:protein localization to organelle; IMP:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   RAB41_HUMAN             Reviewed;         222 AA.
AC   Q5JT25; Q17RQ0;
DE   RecName: Full=Ras-related protein Rab-41;
GN   Name=RAB41;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB44_HUMAN             Reviewed;         723 AA.
AC   Q7Z6P3;
DE   RecName: Full=Ras-related protein Rab-44;
GN   Name=RAB44;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB43_HUMAN             Reviewed;         212 AA.
AC   Q86YS6; A8K4P9; E9PBQ0;
DE   RecName: Full=Ras-related protein Rab-43;
DE   AltName: Full=Ras-related protein Rab-41;
GN   Name=RAB43; Synonyms=RAB41;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0090382; P:phagosome maturation; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0035526; P:retrograde transport, plasma membrane to Golgi; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB42_HUMAN             Reviewed;         105 AA.
AC   Q8N4Z0; B2R5G2;
DE   RecName: Full=Putative Ras-related protein Rab-42;
GN   Name=RAB42;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB4A_HUMAN             Reviewed;         218 AA.
AC   P20338; Q5T7P7; Q9BQ44;
DE   RecName: Full=Ras-related protein Rab-4A;
GN   Name=RAB4A; Synonyms=RAB4;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB4B_HUMAN             Reviewed;         213 AA.
AC   P61018; P22750; Q7Z514; Q9HBR6;
DE   RecName: Full=Ras-related protein Rab-4B;
GN   Name=RAB4B; ORFNames=PP1596;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046323; P:glucose import; IMP:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB5A_HUMAN             Reviewed;         215 AA.
AC   P20339; Q6FI44;
DE   RecName: Full=Ras-related protein Rab-5A;
GN   Name=RAB5A; Synonyms=RAB5;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006897; P:endocytosis; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:2000286; P:receptor internalization involved in canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0051489; P:regulation of filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB5B_HUMAN             Reviewed;         215 AA.
AC   P61020; A8K982; B4DKD7; P35239; P35277; Q6PIK9; Q86TH0; Q8IXL2;
DE   RecName: Full=Ras-related protein Rab-5B;
GN   Name=RAB5B;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0007032; P:endosome organization; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB5C_HUMAN             Reviewed;         216 AA.
AC   P51148; F8W1H5; Q6FH55; Q9P0Y5;
DE   RecName: Full=Ras-related protein Rab-5C;
DE   AltName: Full=L1880;
DE   AltName: Full=RAB5L;
GN   Name=RAB5C; Synonyms=RABL;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0007032; P:endosome organization; IEA:Ensembl.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB6A_HUMAN             Reviewed;         208 AA.
AC   P20340; A8K133; B7Z772; F5H668; Q1W5D8; Q5U0A8; Q9UBE4;
DE   RecName: Full=Ras-related protein Rab-6A;
DE            Short=Rab-6;
GN   Name=RAB6A; Synonyms=RAB6;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; TAS:BHF-UCL.
DR   GO; GO:0018125; P:peptidyl-cysteine methylation; IDA:MGI.
DR   GO; GO:0034067; P:protein localization to Golgi apparatus; IDA:BHF-UCL.
DR   GO; GO:0000042; P:protein targeting to Golgi; IDA:UniProtKB.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:BHF-UCL.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB6B_HUMAN             Reviewed;         208 AA.
AC   Q9NRW1; B2R5Z9; D3DND3; Q92929;
DE   RecName: Full=Ras-related protein Rab-6B;
GN   Name=RAB6B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB6C_HUMAN             Reviewed;         254 AA.
AC   Q9H0N0; Q53RU3; Q6FIF7; Q9P128;
DE   RecName: Full=Ras-related protein Rab-6C;
DE   AltName: Full=Rab6-like protein WTH3;
GN   Name=RAB6C; Synonyms=WTH3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0022402; P:cell cycle process; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:UniProtKB.
//
ID   RAB7A_HUMAN             Reviewed;         207 AA.
AC   P51149; A8K3V6; Q9NWJ0; Q9UPB0;
DE   RecName: Full=Ras-related protein Rab-7a;
GN   Name=RAB7A; Synonyms=RAB7;
DR   GO; GO:0019003; F:GDP binding; IDA:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0003924; F:GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:BHF-UCL.
DR   GO; GO:0007174; P:epidermal growth factor catabolic process; IMP:BHF-UCL.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0090383; P:phagosome acidification; IMP:UniProtKB.
DR   GO; GO:0090382; P:phagosome maturation; TAS:UniProtKB.
DR   GO; GO:0090385; P:phagosome-lysosome fusion; IMP:UniProtKB.
DR   GO; GO:0006622; P:protein targeting to lysosome; IMP:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB7B_HUMAN             Reviewed;         199 AA.
AC   Q96AH8;
DE   RecName: Full=Ras-related protein Rab-7b;
GN   Name=RAB7B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034499; P:late endosome to Golgi transport; IMP:UniProtKB.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IMP:UniProtKB.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB7L_HUMAN             Reviewed;         203 AA.
AC   O14966; B4E1K3; C9JE77;
DE   RecName: Full=Ras-related protein Rab-7L1;
DE   AltName: Full=Rab-7-like protein 1;
GN   Name=RAB7L1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB8A_HUMAN             Reviewed;         207 AA.
AC   P61006; P24407; Q6FHV5;
DE   RecName: Full=Ras-related protein Rab-8A;
DE   AltName: Full=Oncogene c-mel;
DE   Flags: Precursor;
GN   Name=RAB8A; Synonyms=MEL, RAB8;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; ISS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048210; P:Golgi vesicle fusion to target membrane; IDA:BHF-UCL.
DR   GO; GO:0006184; P:GTP catabolic process; EXP:GOC.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051223; P:regulation of protein transport; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IDA:BHF-UCL.
//
ID   RAB8B_HUMAN             Reviewed;         207 AA.
AC   Q92930; Q5JPC4; Q9P293;
DE   RecName: Full=Ras-related protein Rab-8B;
DE   Flags: Precursor;
GN   Name=RAB8B;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0034332; P:adherens junction organization; ISS:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0031346; P:positive regulation of cell projection organization; IEA:Ensembl.
DR   GO; GO:0051461; P:positive regulation of corticotropin secretion; IEA:Ensembl.
DR   GO; GO:0045046; P:protein import into peroxisome membrane; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB9A_HUMAN             Reviewed;         201 AA.
AC   P51151; A8K390; Q6ICN1;
DE   RecName: Full=Ras-related protein Rab-9A;
GN   Name=RAB9A; Synonyms=RAB9;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RAB9B_HUMAN             Reviewed;         201 AA.
AC   Q9NP90; B2R8M0; Q52LX2;
DE   RecName: Full=Ras-related protein Rab-9B;
DE   AltName: Full=Rab-9-like protein;
DE            Short=Rab-9L;
GN   Name=RAB9B; Synonyms=RAB9L;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RABE2_HUMAN             Reviewed;         569 AA.
AC   Q9H5N1;
DE   RecName: Full=Rab GTPase-binding effector protein 2;
DE   AltName: Full=Rabaptin-5beta;
GN   Name=RABEP2; Synonyms=RABPT5B;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RABE1_HUMAN             Reviewed;         862 AA.
AC   Q15276; B2RAG7; O95369; Q8IVX3;
DE   RecName: Full=Rab GTPase-binding effector protein 1;
DE   AltName: Full=Rabaptin-4;
DE   AltName: Full=Rabaptin-5;
DE   AltName: Full=Rabaptin-5alpha;
DE   AltName: Full=Renal carcinoma antigen NY-REN-17;
GN   Name=RABEP1; Synonyms=RAB5EP, RABPT5, RABPT5A;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RABEK_HUMAN             Reviewed;         372 AA.
AC   Q7Z6M1; A8K403; O00568; Q69YR2; Q6FHA4; Q6IBG7; Q6P092; Q86Y76;
AC   Q9BWB1;
DE   RecName: Full=Rab9 effector protein with kelch motifs;
DE   AltName: Full=40 kDa Rab9 effector protein;
DE   AltName: Full=p40;
GN   Name=RABEPK; Synonyms=RAB9P40;
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; TAS:ProtInc.
//
ID   RABL3_HUMAN             Reviewed;         236 AA.
AC   Q5HYI8; Q8WUD3;
DE   RecName: Full=Rab-like protein 3;
GN   Name=RABL3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RABL6_HUMAN             Reviewed;         729 AA.
AC   Q3YEC7; A8QVZ7; A8QVZ8; C6K8I4; C6K8I5; Q4F968; Q5T5R7; Q8IWK1;
AC   Q8TCL4; Q8WU94; Q96SR8; Q9BU21; Q9H935;
DE   RecName: Full=Rab-like protein 6;
DE   AltName: Full=GTP-binding protein Parf;
DE   AltName: Full=Partner of ARF;
DE   AltName: Full=Rab-like protein 1;
DE            Short=RBEL1;
GN   Name=RABL6; Synonyms=C9orf86, PARF;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RABP1_HUMAN             Reviewed;         137 AA.
AC   P29762; Q6IAY7; Q8WTV5;
DE   RecName: Full=Cellular retinoic acid-binding protein 1;
DE   AltName: Full=Cellular retinoic acid-binding protein I;
DE            Short=CRABP-I;
GN   Name=CRABP1; Synonyms=RBP5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0001972; F:retinoic acid binding; IEA:Ensembl.
DR   GO; GO:0005501; F:retinoid binding; TAS:ProtInc.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RABP2_HUMAN             Reviewed;         138 AA.
AC   P29373; B2R4Z8; D3DVC5; F1T098; Q6ICN6;
DE   RecName: Full=Cellular retinoic acid-binding protein 2;
DE   AltName: Full=Cellular retinoic acid-binding protein II;
DE            Short=CRABP-II;
GN   Name=CRABP2;
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0001972; F:retinoic acid binding; IEA:Ensembl.
DR   GO; GO:0005501; F:retinoid binding; TAS:ProtInc.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RABX5_HUMAN             Reviewed;         708 AA.
AC   Q9UJ41; B4DZM7; Q3HKR2; Q3HKR3; Q53FG0;
DE   RecName: Full=Rab5 GDP/GTP exchange factor;
DE   AltName: Full=RAP1;
DE   AltName: Full=Rabaptin-5-associated exchange factor for Rab5;
DE   AltName: Full=Rabex-5;
GN   Name=RABGEF1; Synonyms=RABEX5;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   RAC1_HUMAN              Reviewed;         192 AA.
AC   P63000; O95501; P15154; Q3Y4D3; Q5JAA8; Q9BTB4;
DE   RecName: Full=Ras-related C3 botulinum toxin substrate 1;
DE   AltName: Full=Cell migration-inducing gene 5 protein;
DE   AltName: Full=Ras-like protein TC25;
DE   AltName: Full=p21-Rac1;
DE   Flags: Precursor;
GN   Name=RAC1; Synonyms=TC25; ORFNames=MIG5;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051022; F:Rho GDP-dissociation inhibitor binding; ISS:UniProtKB.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IGI:MGI.
DR   GO; GO:0030041; P:actin filament polymerization; TAS:UniProtKB.
DR   GO; GO:0048532; P:anatomical structure arrangement; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0002093; P:auditory receptor cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0048870; P:cell motility; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0021799; P:cerebral cortex radially oriented cell migration; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021831; P:embryonic olfactory bulb interneuron precursor migration; IEA:Ensembl.
DR   GO; GO:0043652; P:engulfment of apoptotic cell; IEA:Ensembl.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.
DR   GO; GO:0051668; P:localization within membrane; IMP:BHF-UCL.
DR   GO; GO:0002551; P:mast cell chemotaxis; IEA:Ensembl.
DR   GO; GO:0032707; P:negative regulation of interleukin-23 production; IDA:BHF-UCL.
DR   GO; GO:0048261; P:negative regulation of receptor-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.
DR   GO; GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
DR   GO; GO:0097178; P:ruffle assembly; IEA:Ensembl.
DR   GO; GO:0031529; P:ruffle organization; TAS:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   RAC2_HUMAN              Reviewed;         192 AA.
AC   P15153; Q9UDJ4;
DE   RecName: Full=Ras-related C3 botulinum toxin substrate 2;
DE   AltName: Full=GX;
DE   AltName: Full=Small G protein;
DE   AltName: Full=p21-Rac2;
DE   Flags: Precursor;
GN   Name=RAC2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0030031; P:cell projection assembly; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010310; P:regulation of hydrogen peroxide metabolic process; TAS:BHF-UCL.
DR   GO; GO:0060263; P:regulation of respiratory burst; IDA:BHF-UCL.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RAC3_HUMAN              Reviewed;         192 AA.
AC   P60763; O14658; Q5U0M8;
DE   RecName: Full=Ras-related C3 botulinum toxin substrate 3;
DE   AltName: Full=p21-Rac3;
DE   Flags: Precursor;
GN   Name=RAC3;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0030031; P:cell projection assembly; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IDA:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RAD17_HUMAN             Reviewed;         681 AA.
AC   O75943; A8K8X2; D3DWA5; O75714; Q7Z3S4; Q9UNK7; Q9UNR7; Q9UNR8;
AC   Q9UPF5;
DE   RecName: Full=Cell cycle checkpoint protein RAD17;
DE            Short=hRad17;
DE   AltName: Full=RF-C/activator 1 homolog;
GN   Name=RAD17; Synonyms=R24L;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000076; P:DNA replication checkpoint; TAS:ProtInc.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.
DR   GO; GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.
//
ID   RAD18_HUMAN             Reviewed;         495 AA.
AC   Q9NS91; Q58F55; Q9NRT6;
DE   RecName: Full=E3 ubiquitin-protein ligase RAD18;
DE            EC=6.3.2.-;
DE   AltName: Full=Postreplication repair protein RAD18;
DE            Short=hHR18;
DE            Short=hRAD18;
DE   AltName: Full=RING finger protein 73;
GN   Name=RAD18; Synonyms=RNF73;
DR   GO; GO:0003684; F:damaged DNA binding; NAS:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   RAD1_HUMAN              Reviewed;         282 AA.
AC   O60671; O75572; O95304; Q1W161; Q5KSM0; Q5KSM1; Q9UEP1;
DE   RecName: Full=Cell cycle checkpoint protein RAD1;
DE            Short=hRAD1;
DE            EC=3.1.11.2;
DE   AltName: Full=DNA repair exonuclease rad1 homolog;
DE   AltName: Full=Rad1-like DNA damage checkpoint protein;
GN   Name=RAD1; Synonyms=REC1;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; NAS:UniProtKB.
DR   GO; GO:0008853; F:exodeoxyribonuclease III activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; NAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0007128; P:meiotic prophase I; TAS:ProtInc.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   RAD21_HUMAN             Reviewed;         631 AA.
AC   O60216; A8K0E0; Q15001; Q99568;
DE   RecName: Full=Double-strand-break repair protein rad21 homolog;
DE            Short=hHR21;
DE   AltName: Full=Nuclear matrix protein 1;
DE            Short=NXP-1;
DE   AltName: Full=SCC1 homolog;
GN   Name=RAD21; Synonyms=HR21, KIAA0078, NXP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006302; P:double-strand break repair; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0071168; P:protein localization to chromatin; IMP:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   RAD50_HUMAN             Reviewed;        1312 AA.
AC   Q92878; B9EGF5; O43254; Q6GMT7; Q6P5X3; Q9UP86;
DE   RecName: Full=DNA repair protein RAD50;
DE            Short=hRAD50;
DE            EC=3.6.-.-;
GN   Name=RAD50;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0032508; P:DNA duplex unwinding; IMP:BHF-UCL.
DR   GO; GO:0006310; P:DNA recombination; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IDA:BHF-UCL.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0000019; P:regulation of mitotic recombination; IDA:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:BHF-UCL.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; IDA:UniProtKB.
//
ID   RAD52_HUMAN             Reviewed;         418 AA.
AC   P43351; Q13205; Q9Y5T7; Q9Y5T8; Q9Y5T9;
DE   RecName: Full=DNA repair protein RAD52 homolog;
GN   Name=RAD52;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000730; P:DNA recombinase assembly; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0006312; P:mitotic recombination; TAS:ProtInc.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
//
ID   RAD51_HUMAN             Reviewed;         339 AA.
AC   Q06609; B0FXP0; B2R8T6; Q6FHX9; Q6ZNA8; Q9BV60;
DE   RecName: Full=DNA repair protein RAD51 homolog 1;
DE            Short=HsRAD51;
DE            Short=hRAD51;
DE   AltName: Full=RAD51 homolog A;
GN   Name=RAD51; Synonyms=RAD51A, RECA;
DR   GO; GO:0005524; F:ATP binding; IDA:MGI.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0070182; F:DNA polymerase binding; IPI:UniProt.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0043142; F:single-stranded DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0072757; P:cellular response to camptothecin; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000730; P:DNA recombinase assembly; TAS:Reactome.
DR   GO; GO:0006310; P:DNA recombination; TAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0006312; P:mitotic recombination; TAS:ProtInc.
DR   GO; GO:0051106; P:positive regulation of DNA ligation; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.
//
ID   RAD54_HUMAN             Reviewed;         747 AA.
AC   Q92698; Q5TE31; Q6IUY3;
DE   RecName: Full=DNA repair and recombination protein RAD54-like;
DE            EC=3.6.4.-;
DE   AltName: Full=RAD54 homolog;
DE            Short=hHR54;
DE            Short=hRAD54;
GN   Name=RAD54L; Synonyms=RAD54A;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:GOC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
//
ID   RAD9A_HUMAN             Reviewed;         391 AA.
AC   Q99638; B2RCZ8; Q6FI29; Q96C41;
DE   RecName: Full=Cell cycle checkpoint control protein RAD9A;
DE            Short=hRAD9;
DE            EC=3.1.11.2;
DE   AltName: Full=DNA repair exonuclease rad9 homolog A;
GN   Name=RAD9A;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0008853; F:exodeoxyribonuclease III activity; IEA:UniProtKB-EC.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0000076; P:DNA replication checkpoint; TAS:ProtInc.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:1902231; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
//
ID   RAD9B_HUMAN             Reviewed;         426 AA.
AC   Q6WBX8; Q5U5K0; Q6NVJ1; Q6ZVT7; Q8N7T9; Q96LI8;
DE   RecName: Full=Cell cycle checkpoint control protein RAD9B;
DE   AltName: Full=DNA repair exonuclease rad9 homolog B;
DE            Short=hRAD9B;
GN   Name=RAD9B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
//
ID   RADIL_HUMAN             Reviewed;        1075 AA.
AC   Q96JH8; A4D1Z5; A5YM49; B7ZL20; Q0VFZ9; Q75LH3; Q9BSP5; Q9H0M6;
AC   Q9NW43; Q9NWC4;
DE   RecName: Full=Ras-associating and dilute domain-containing protein;
GN   Name=RADIL; Synonyms=KIAA1849;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:MGI.
//
ID   RADI_HUMAN              Reviewed;         583 AA.
AC   P35241; A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; Q86Y61;
DE   RecName: Full=Radixin;
GN   Name=RDX;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0045176; P:apical protein localization; IEA:Ensembl.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IGI:UniProt.
DR   GO; GO:0030033; P:microvillus assembly; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IGI:UniProt.
//
ID   RAD_HUMAN               Reviewed;         308 AA.
AC   P55042; Q96F39;
DE   RecName: Full=GTP-binding protein RAD;
DE   AltName: Full=RAD1;
DE   AltName: Full=Ras associated with diabetes;
GN   Name=RRAD; Synonyms=RAD;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   RAE1L_HUMAN             Reviewed;         368 AA.
AC   P78406; A8K882; O15306; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6;
DE   RecName: Full=mRNA export factor;
DE   AltName: Full=Rae1 protein homolog;
DE   AltName: Full=mRNA-associated protein mrnp 41;
GN   Name=RAE1; Synonyms=MRNP41;
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:ProtInc.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RAE1_HUMAN              Reviewed;         653 AA.
AC   P24386; A1L4D2; O43732;
DE   RecName: Full=Rab proteins geranylgeranyltransferase component A 1;
DE   AltName: Full=Choroideremia protein;
DE   AltName: Full=Rab escort protein 1;
DE            Short=REP-1;
DE   AltName: Full=TCD protein;
GN   Name=CHM; Synonyms=REP1, TCD;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0004663; F:Rab geranylgeranyltransferase activity; TAS:ProtInc.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0018344; P:protein geranylgeranylation; IDA:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RAE2_HUMAN              Reviewed;         656 AA.
AC   P26374; B2RAB9; Q17RE0; Q9H1Y4;
DE   RecName: Full=Rab proteins geranylgeranyltransferase component A 2;
DE   AltName: Full=Choroideremia-like protein;
DE   AltName: Full=Rab escort protein 2;
DE            Short=REP-2;
GN   Name=CHML; Synonyms=REP2;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0004663; F:Rab geranylgeranyltransferase activity; IEA:InterPro.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0018344; P:protein geranylgeranylation; IDA:UniProtKB.
//
ID   RAF1_HUMAN              Reviewed;         648 AA.
AC   P04049; B0LPH8; B2R5N3; Q15278; Q9UC20;
DE   RecName: Full=RAF proto-oncogene serine/threonine-protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Proto-oncogene c-RAF;
DE            Short=cRaf;
DE   AltName: Full=Raf-1;
GN   Name=RAF1; Synonyms=RAF;
DR   GuidetoPHARMACOLOGY; 2184; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; NAS:BHF-UCL.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071550; P:death-inducing signaling complex assembly; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:UniProtKB.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; TAS:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; TAS:UniProtKB.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; TAS:UniProtKB.
//
ID   RAG1_HUMAN              Reviewed;        1043 AA.
AC   P15918; Q8NER2;
DE   RecName: Full=V(D)J recombination-activating protein 1;
DE            Short=RAG-1;
DE   AltName: Full=RING finger protein 74;
DE   Includes:
DE     RecName: Full=Endonuclease RAG1;
DE              EC=3.1.-.-;
DE   Includes:
DE     RecName: Full=E3 ubiquitin-protein ligase RAG1;
DE              EC=6.3.2.-;
GN   Name=RAG1; Synonyms=RNF74;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004519; F:endonuclease activity; ISS:UniProtKB.
DR   GO; GO:0042393; F:histone binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; ISS:GOC.
DR   GO; GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
DR   GO; GO:0045580; P:regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
//
ID   RAG2_HUMAN              Reviewed;         527 AA.
AC   P55895; A8K9E9; Q8TBL4;
DE   RecName: Full=V(D)J recombination-activating protein 2;
DE            Short=RAG-2;
GN   Name=RAG2;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0035064; F:methylated histone binding; ISS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0002358; P:B cell homeostatic proliferation; IEA:Ensembl.
DR   GO; GO:0002326; P:B cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0002360; P:T cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
//
ID   RAGE_HUMAN              Reviewed;         404 AA.
AC   Q15109; A2BFI7; A6NKF0; A7Y2U9; B0V176; Q15279; Q3L1R4; Q3L1R5;
AC   Q3L1R6; Q3L1R7; Q3L1R8; Q3L1S0; Q86SN1; Q9H2X7; Q9Y3R3;
DE   RecName: Full=Advanced glycosylation end product-specific receptor;
DE   AltName: Full=Receptor for advanced glycosylation end products;
DE   Flags: Precursor;
GN   Name=AGER; Synonyms=RAGE;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031175; P:neuron projection development; IGI:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; TAS:ProtInc.
//
ID   RAGP1_HUMAN             Reviewed;         587 AA.
AC   P46060; Q96JJ2;
DE   RecName: Full=Ran GTPase-activating protein 1;
DE            Short=RanGAP1;
GN   Name=RANGAP1; Synonyms=KIAA1835, SD;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005098; F:Ran GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046826; P:negative regulation of protein export from nucleus; IDA:BHF-UCL.
DR   GO; GO:0032853; P:positive regulation of Ran GTPase activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RAI14_HUMAN             Reviewed;         980 AA.
AC   Q9P0K7; E9PED3; Q6V1W9; Q7Z5I4; Q7Z733; Q9P2L2; Q9Y3T5;
DE   RecName: Full=Ankycorbin;
DE   AltName: Full=Ankyrin repeat and coiled-coil structure-containing protein;
DE   AltName: Full=Novel retinal pigment epithelial cell protein;
DE   AltName: Full=Retinoic acid-induced protein 14;
GN   Name=RAI14; Synonyms=KIAA1334, NORPEG;
//
ID   RAI1_HUMAN              Reviewed;        1906 AA.
AC   Q7Z5J4; Q8N3B4; Q8ND08; Q8WU64; Q96JK5; Q9H1C1; Q9H1C2; Q9UF69;
DE   RecName: Full=Retinoic acid-induced protein 1;
GN   Name=RAI1; Synonyms=KIAA1820;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   RAI3_HUMAN              Reviewed;         357 AA.
AC   Q8NFJ5; B3KV45; O95357;
DE   RecName: Full=Retinoic acid-induced protein 3;
DE   AltName: Full=G-protein coupled receptor family C group 5 member A;
DE   AltName: Full=Orphan G-protein-coupling receptor PEIG-1;
DE   AltName: Full=Retinoic acid-induced gene 1 protein;
DE            Short=RAIG-1;
GN   Name=GPRC5A; Synonyms=GPCR5A, RAI3, RAIG1;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RAI2_HUMAN              Reviewed;         530 AA.
AC   Q9Y5P3; B1B1K2; B4DQM9; E7EMN4; Q8N6X7;
DE   RecName: Full=Retinoic acid-induced protein 2;
GN   Name=RAI2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
//
ID   RAKDN_HUMAN             Reviewed;         111 AA.
AC   A6NC62; Q8N0T3;
DE   RecName: Full=Putative RBAK downstream neighbor protein;
GN   Name=RBAKDN;
//
ID   RALA_HUMAN              Reviewed;         206 AA.
AC   P11233; A4D1W3;
DE   RecName: Full=Ras-related protein Ral-A;
DE   Flags: Precursor;
GN   Name=RALA; Synonyms=RAL;
DR   GO; GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0051665; P:membrane raft localization; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0017157; P:regulation of exocytosis; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RALB_HUMAN              Reviewed;         206 AA.
AC   P11234; Q53T32;
DE   RecName: Full=Ras-related protein Ral-B;
DE   Flags: Precursor;
GN   Name=RALB;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0001928; P:regulation of exocyst assembly; ISS:UniProtKB.
DR   GO; GO:0060178; P:regulation of exocyst localization; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RAIN_HUMAN              Reviewed;         963 AA.
AC   Q5U651; Q6U676;
DE   RecName: Full=Ras-interacting protein 1;
DE            Short=Rain;
GN   Name=RASIP1;
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; ISS:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:BHF-UCL.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
//
ID   RALYL_HUMAN             Reviewed;         291 AA.
AC   Q86SE5; B3KTH2; G3V129; Q6ZW87; Q8N1C2;
DE   RecName: Full=RNA-binding Raly-like protein;
DE            Short=hRALYL;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein C-like 3;
DE            Short=hnRNP core protein C-like 3;
GN   Name=RALYL; Synonyms=HNRPCL3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RAMP1_HUMAN             Reviewed;         148 AA.
AC   O60894; Q6FGS5;
DE   RecName: Full=Receptor activity-modifying protein 1;
DE   AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 1;
DE            Short=CRLR activity-modifying protein 1;
DE   Flags: Precursor;
GN   Name=RAMP1;
DR   GO; GO:0004948; F:calcitonin receptor activity; IDA:UniProtKB.
DR   GO; GO:0031716; F:calcitonin receptor binding; IPI:UniProtKB.
DR   GO; GO:0015026; F:coreceptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0060050; P:positive regulation of protein glycosylation; IDA:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
//
ID   RALY_HUMAN              Reviewed;         306 AA.
AC   Q9UKM9; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3;
DE   RecName: Full=RNA-binding protein Raly;
DE   AltName: Full=Autoantigen p542;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein C-like 2;
DE            Short=hnRNP core protein C-like 2;
DE   AltName: Full=hnRNP associated with lethal yellow protein homolog;
GN   Name=RALY; Synonyms=HNRPCL2, P542;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   RAM_HUMAN               Reviewed;         118 AA.
AC   Q9BTL3; Q2M1J8;
DE   RecName: Full=RNMT-activating mini protein;
DE            Short=RAM;
DE   AltName: Full=Protein FAM103A1;
GN   Name=FAM103A1; Synonyms=C15orf18;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; IDA:UniProtKB.
DR   GO; GO:0032259; P:methylation; IMP:UniProtKB.
DR   GO; GO:0036031; P:recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex; IDA:UniProtKB.
//
ID   RAMP3_HUMAN             Reviewed;         148 AA.
AC   O60896; Q7Z2Y1;
DE   RecName: Full=Receptor activity-modifying protein 3;
DE   AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 3;
DE            Short=CRLR activity-modifying protein 3;
DE   Flags: Precursor;
GN   Name=RAMP3;
DR   GO; GO:0015026; F:coreceptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; ISS:UniProtKB.
DR   GO; GO:0086103; P:G-protein coupled receptor signaling pathway involved in heart process; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IDA:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:InterPro.
//
ID   RAMP2_HUMAN             Reviewed;         175 AA.
AC   O60895; Q8N1F2;
DE   RecName: Full=Receptor activity-modifying protein 2;
DE   AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 2;
DE            Short=CRLR activity-modifying protein 2;
DE   Flags: Precursor;
GN   Name=RAMP2;
DR   GO; GO:0015026; F:coreceptor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0034333; P:adherens junction assembly; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0070831; P:basement membrane assembly; ISS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:InterPro.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; IDA:UniProtKB.
DR   GO; GO:0097084; P:vascular smooth muscle cell development; ISS:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; IMP:UniProtKB.
//
ID   RANB3_HUMAN             Reviewed;         567 AA.
AC   Q9H6Z4; B2RAT8; O60405; O75759; O75760; Q9BT47; Q9UG74;
DE   RecName: Full=Ran-binding protein 3;
DE            Short=RanBP3;
GN   Name=RANBP3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:UniProtKB.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RANB9_HUMAN             Reviewed;         729 AA.
AC   Q96S59; A0PJA2; O94764; Q6P3T7; Q7LBR2; Q7Z7F9;
DE   RecName: Full=Ran-binding protein 9;
DE            Short=RanBP9;
DE   AltName: Full=BPM-L;
DE   AltName: Full=BPM90;
DE   AltName: Full=Ran-binding protein M;
DE            Short=RanBPM;
DE   AltName: Full=RanBP7;
GN   Name=RANBP9; Synonyms=RANBPM;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; NAS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   RANG_HUMAN              Reviewed;         201 AA.
AC   P43487;
DE   RecName: Full=Ran-specific GTPase-activating protein;
DE   AltName: Full=Ran-binding protein 1;
DE            Short=RanBP1;
GN   Name=RANBP1;
DR   GO; GO:0005092; F:GDP-dissociation inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR   GO; GO:0046604; P:positive regulation of mitotic centrosome separation; IEA:Ensembl.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RAN_HUMAN               Reviewed;         216 AA.
AC   P62826; A8K3Z8; P17080; P28746; P28747; Q6IPB2; Q86V08; Q8NI90;
AC   Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9;
DE   RecName: Full=GTP-binding nuclear protein Ran;
DE   AltName: Full=Androgen receptor-associated protein 24;
DE   AltName: Full=GTPase Ran;
DE   AltName: Full=Ras-like protein TC4;
DE   AltName: Full=Ras-related nuclear protein;
GN   Name=RAN; Synonyms=ARA24; ORFNames=OK/SW-cl.81;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; TAS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:UniProtKB.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RAP1A_HUMAN             Reviewed;         184 AA.
AC   P62834; P10113;
DE   RecName: Full=Ras-related protein Rap-1A;
DE   AltName: Full=C21KG;
DE   AltName: Full=G-22K;
DE   AltName: Full=GTP-binding protein smg p21A;
DE   AltName: Full=Ras-related protein Krev-1;
DE   Flags: Precursor;
GN   Name=RAP1A; Synonyms=KREV1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProtKB.
DR   GO; GO:0038180; P:nerve growth factor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; ISS:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; IMP:UniProtKB.
DR   GO; GO:1901888; P:regulation of cell junction assembly; IMP:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RAP1B_HUMAN             Reviewed;         184 AA.
AC   P61224; B2R5Z2; B4DQI8; B4DW74; B4DW94; P09526; Q502X3; Q5TZR4;
AC   Q6DCA1; Q6LES0;
DE   RecName: Full=Ras-related protein Rap-1b;
DE   AltName: Full=GTP-binding protein smg p21B;
DE   Flags: Precursor;
GN   Name=RAP1B; ORFNames=OK/SW-cl.11;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0032486; P:Rap protein signal transduction; IMP:UniProtKB.
DR   GO; GO:1901888; P:regulation of cell junction assembly; IMP:UniProtKB.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RAP2A_HUMAN             Reviewed;         183 AA.
AC   P10114; B2RCJ1; Q5JSC1; Q5JSC2;
DE   RecName: Full=Ras-related protein Rap-2a;
DE   AltName: Full=RbBP-30;
DE   Flags: Precursor;
GN   Name=RAP2A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IDA:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; IDA:MGI.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB.
DR   GO; GO:0046328; P:regulation of JNK cascade; IDA:UniProtKB.
//
ID   RAP2B_HUMAN             Reviewed;         183 AA.
AC   P61225; P17964; Q96EG5; Q9CXG0;
DE   RecName: Full=Ras-related protein Rap-2b;
DE   Flags: Precursor;
GN   Name=RAP2B;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProt.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RAP2C_HUMAN             Reviewed;         183 AA.
AC   Q9Y3L5; B3KWD6; Q5H9H9; Q9BTS0;
DE   RecName: Full=Ras-related protein Rap-2c;
DE   Flags: Precursor;
GN   Name=RAP2C;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProt.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProt.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0061097; P:regulation of protein tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IDA:GOC.
//
ID   RAPH1_HUMAN             Reviewed;        1250 AA.
AC   Q70E73; Q96Q37; Q9C0I2;
DE   RecName: Full=Ras-associated and pleckstrin homology domains-containing protein 1;
DE            Short=RAPH1;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein;
DE   AltName: Full=Lamellipodin;
DE   AltName: Full=Proline-rich EVH1 ligand 2;
DE            Short=PREL-2;
DE   AltName: Full=Protein RMO1;
GN   Name=RAPH1; Synonyms=ALS2CR18, ALS2CR9, KIAA1681, LPD, PREL2, RMO1;
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RAPSN_HUMAN             Reviewed;         412 AA.
AC   Q13702; Q8TDF3; Q9BTD9;
DE   RecName: Full=43 kDa receptor-associated protein of the synapse;
DE            Short=RAPsyn;
DE   AltName: Full=43 kDa postsynaptic protein;
DE   AltName: Full=Acetylcholine receptor-associated 43 kDa protein;
DE   AltName: Full=RING finger protein 205;
GN   Name=RAPSN; Synonyms=RNF205;
DR   GO; GO:0033130; F:acetylcholine receptor binding; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IGI:MGI.
//
ID   RARA_HUMAN              Reviewed;         462 AA.
AC   P10276; B8Y636; P78456; Q13440; Q13441; Q96S41; Q9NQS0;
DE   RecName: Full=Retinoic acid receptor alpha;
DE            Short=RAR-alpha;
DE   AltName: Full=Nuclear receptor subfamily 1 group B member 1;
GN   Name=RARA; Synonyms=NR1B1;
DR   GuidetoPHARMACOLOGY; 590; -.
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IEA:Ensembl.
DR   GO; GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; IDA:UniProtKB.
DR   GO; GO:0043422; F:protein kinase B binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0003708; F:retinoic acid receptor activity; IDA:BHF-UCL.
DR   GO; GO:0044323; F:retinoic acid-responsive element binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043277; P:apoptotic cell clearance; IMP:UniProtKB.
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0060591; P:chondroblast differentiation; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030853; P:negative regulation of granulocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0051099; P:positive regulation of binding; IMP:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0032736; P:positive regulation of interleukin-13 production; IDA:BHF-UCL.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IDA:BHF-UCL.
DR   GO; GO:0032754; P:positive regulation of interleukin-5 production; IDA:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030850; P:prostate gland development; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0060010; P:Sertoli cell fate commitment; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IDA:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; IEA:Ensembl.
//
ID   RARB_HUMAN              Reviewed;         455 AA.
AC   P10826; P12891; Q00989; Q15298; Q9UN48;
DE   RecName: Full=Retinoic acid receptor beta;
DE            Short=RAR-beta;
DE   AltName: Full=HBV-activated protein;
DE   AltName: Full=Nuclear receptor subfamily 1 group B member 2;
DE   AltName: Full=RAR-epsilon;
GN   Name=RARB; Synonyms=HAP, NR1B2;
DR   GuidetoPHARMACOLOGY; 591; -.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003708; F:retinoic acid receptor activity; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048566; P:embryonic digestive tract development; IMP:DFLAT.
DR   GO; GO:0048048; P:embryonic eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; IEA:Ensembl.
//
ID   RARG_HUMAN              Reviewed;         454 AA.
AC   P13631; B7Z492; B7Z4F1; B7ZAE4; J3KNP6; P22932; Q15281; Q52LZ8;
AC   Q9BYX8; Q9H1I3; Q9UJ38;
DE   RecName: Full=Retinoic acid receptor gamma;
DE            Short=RAR-gamma;
DE   AltName: Full=Nuclear receptor subfamily 1 group B member 3;
GN   Name=RARG; Synonyms=NR1B3;
DR   GuidetoPHARMACOLOGY; 592; -.
DR   GO; GO:0003677; F:DNA binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003708; F:retinoic acid receptor activity; IEA:Ensembl.
DR   GO; GO:0046965; F:retinoid X receptor binding; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0048048; P:embryonic eye morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0003430; P:growth plate cartilage chondrocyte growth; IEA:Ensembl.
DR   GO; GO:0070384; P:Harderian gland development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0008361; P:regulation of cell size; TAS:BHF-UCL.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060534; P:trachea cartilage development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   RARR2_HUMAN             Reviewed;         163 AA.
AC   Q99969; Q7LE02;
DE   RecName: Full=Retinoic acid receptor responder protein 2;
DE   AltName: Full=Chemerin;
DE   AltName: Full=RAR-responsive protein TIG2;
DE   AltName: Full=Tazarotene-induced gene 2 protein;
DE   Flags: Precursor;
GN   Name=RARRES2; Synonyms=TIG2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0048566; P:embryonic digestive tract development; IMP:DFLAT.
DR   GO; GO:0001701; P:in utero embryonic development; IEP:DFLAT.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; ISS:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IDA:UniProtKB.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; IMP:DFLAT.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050994; P:regulation of lipid catabolic process; ISS:UniProtKB.
DR   GO; GO:0001523; P:retinoid metabolic process; IDA:UniProtKB.
//
ID   RAS4B_HUMAN             Reviewed;         803 AA.
AC   C9J798;
DE   RecName: Full=Putative Ras GTPase-activating protein 4B;
GN   Name=RASA4B;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RASA1_HUMAN             Reviewed;        1047 AA.
AC   P20936; B2R6W3; Q9UDI1;
DE   RecName: Full=Ras GTPase-activating protein 1;
DE            Short=GAP;
DE            Short=GTPase-activating protein;
DE            Short=RasGAP;
DE   AltName: Full=Ras p21 protein activator;
DE   AltName: Full=p120GAP;
GN   Name=RASA1; Synonyms=GAP, RASA;
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProtKB.
DR   GO; GO:0051020; F:GTPase binding; IPI:UniProtKB.
DR   GO; GO:0019870; F:potassium channel inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0000281; P:mitotic cytokinesis; ISS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; NAS:UniProtKB.
DR   GO; GO:0051252; P:regulation of RNA metabolic process; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
//
ID   RASA3_HUMAN             Reviewed;         834 AA.
AC   Q14644; A6NL15; Q8IUY2;
DE   RecName: Full=Ras GTPase-activating protein 3;
DE   AltName: Full=GAP1(IP4BP);
DE   AltName: Full=Ins P4-binding protein;
GN   Name=RASA3;
DR   GO; GO:0015278; F:calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RASD1_HUMAN             Reviewed;         281 AA.
AC   Q9Y272; B2R709; B4DFF4; Q9NYB4;
DE   RecName: Full=Dexamethasone-induced Ras-related protein 1;
DE   AltName: Full=Activator of G-protein signaling 1;
DE   Flags: Precursor;
GN   Name=RASD1; Synonyms=AGS1, DEXRAS1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007263; P:nitric oxide mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RASE_HUMAN              Reviewed;         233 AA.
AC   Q7Z444;
DE   RecName: Full=GTPase ERas;
DE            Short=E-Ras;
DE   AltName: Full=Embryonic stem cell-expressed Ras;
DE   Flags: Precursor;
GN   Name=ERAS; Synonyms=HRAS2, HRASP;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RASEF_HUMAN             Reviewed;         740 AA.
AC   Q8IZ41; A6NC29; Q96N04;
DE   RecName: Full=Ras and EF-hand domain-containing protein;
DE   AltName: Full=Ras-related protein Rab-45;
GN   Name=RASEF; Synonyms=RAB45;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RASF1_HUMAN             Reviewed;         344 AA.
AC   Q9NS23; B7ZLL1; O14571; O60539; O60710; Q0VGC6; Q5TZT2; Q9HB04;
AC   Q9HB18; Q9NS22; Q9UND4; Q9UND5;
DE   RecName: Full=Ras association domain-containing protein 1;
GN   Name=RASSF1; Synonyms=RDA32;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; IDA:UniProtKB.
//
ID   RASA2_HUMAN             Reviewed;         850 AA.
AC   Q15283; A8K7K1; G3V0F9; O00695; Q15284; Q92594; Q99577; Q9UEQ2;
DE   RecName: Full=Ras GTPase-activating protein 2;
DE   AltName: Full=GTPase-activating protein 1m;
DE            Short=GAP1m;
GN   Name=RASA2; Synonyms=GAP1M, RASGAP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RASF2_HUMAN             Reviewed;         326 AA.
AC   P50749; A6NIX9; A8K5Z3; Q17S06; Q53HD0; Q6AHZ2;
DE   RecName: Full=Ras association domain-containing protein 2;
GN   Name=RASSF2; Synonyms=KIAA0168;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASF3_HUMAN             Reviewed;         238 AA.
AC   Q86WH2; Q86WH1;
DE   RecName: Full=Ras association domain-containing protein 3;
GN   Name=RASSF3;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASF5_HUMAN             Reviewed;         418 AA.
AC   Q8WWW0; A8K1E6; Q5SY32; Q8WWV9; Q8WXF4; Q9BT99;
DE   RecName: Full=Ras association domain-containing protein 5;
DE   AltName: Full=New ras effector 1;
DE   AltName: Full=Regulator for cell adhesion and polarization enriched in lymphoid tissues;
DE            Short=RAPL;
GN   Name=RASSF5; Synonyms=NORE1, RAPL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
//
ID   RASF6_HUMAN             Reviewed;         369 AA.
AC   Q6ZTQ3; Q68DT2; Q6PDA6; Q86WG9; Q86WH0;
DE   RecName: Full=Ras association domain-containing protein 6;
GN   Name=RASSF6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASF4_HUMAN             Reviewed;         321 AA.
AC   Q9H2L5; Q86WH5; Q86WH6; Q86WH7; Q8N5A9; Q8TCK6;
DE   RecName: Full=Ras association domain-containing protein 4;
GN   Name=RASSF4; ORFNames=AD037;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASF8_HUMAN             Reviewed;         419 AA.
AC   Q8NHQ8; A8K1Z0; O95647; Q5SCI2; Q76KB6;
DE   RecName: Full=Ras association domain-containing protein 8;
DE   AltName: Full=Carcinoma-associated protein HOJ-1;
GN   Name=RASSF8; Synonyms=C12orf2;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASF9_HUMAN             Reviewed;         435 AA.
AC   O75901; B3KMQ4; Q8N5U8;
DE   RecName: Full=Ras association domain-containing protein 9;
DE   AltName: Full=PAM COOH-terminal interactor protein 1;
DE            Short=P-CIP1;
DE   AltName: Full=Peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor;
GN   Name=RASSF9; Synonyms=PAMCI, PCIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; NAS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; NAS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASFA_HUMAN             Reviewed;         507 AA.
AC   A6NK89;
DE   RecName: Full=Ras association domain-containing protein 10;
GN   Name=RASSF10;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASF7_HUMAN             Reviewed;         373 AA.
AC   Q02833; G5E9N9; Q3KP41; Q3KP42;
DE   RecName: Full=Ras association domain-containing protein 7;
DE   AltName: Full=HRAS1-related cluster protein 1;
GN   Name=RASSF7; Synonyms=C11orf13, HRC1;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASH_HUMAN              Reviewed;         189 AA.
AC   P01112; B5BUA0; Q14080; Q6FHV9; Q9BR65; Q9UCE2;
DE   RecName: Full=GTPase HRas;
DE   AltName: Full=H-Ras-1;
DE   AltName: Full=Ha-Ras;
DE   AltName: Full=Transforming protein p21;
DE   AltName: Full=c-H-ras;
DE   AltName: Full=p21ras;
DE   Contains:
DE     RecName: Full=GTPase HRas, N-terminally processed;
DE   Flags: Precursor;
GN   Name=HRAS; Synonyms=HRAS1;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0090398; P:cellular senescence; IDA:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0034259; P:negative regulation of Rho GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:2000630; P:positive regulation of miRNA metabolic process; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0035022; P:positive regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:1900029; P:positive regulation of ruffle assembly; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0090303; P:positive regulation of wound healing; IDA:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   RASK_HUMAN              Reviewed;         189 AA.
AC   P01116; A8K8Z5; B0LPF9; P01118; Q96D10;
DE   RecName: Full=GTPase KRas;
DE   AltName: Full=K-Ras 2;
DE   AltName: Full=Ki-Ras;
DE   AltName: Full=c-K-ras;
DE   AltName: Full=c-Ki-ras;
DE   Contains:
DE     RecName: Full=GTPase KRas, N-terminally processed;
DE   Flags: Precursor;
GN   Name=KRAS; Synonyms=KRAS2, RASK2;
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0019002; F:GMP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0035022; P:positive regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0051385; P:response to mineralocorticoid; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   RASL2_HUMAN             Reviewed;         803 AA.
AC   O43374; O60286; Q14CQ4; Q86UW3; Q96QU0;
DE   RecName: Full=Ras GTPase-activating protein 4;
DE   AltName: Full=Calcium-promoted Ras inactivator;
DE   AltName: Full=Ras p21 protein activator 4;
DE   AltName: Full=RasGAP-activating-like protein 2;
GN   Name=RASA4; Synonyms=CAPRI, GAPL, KIAA0538;
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
//
ID   RASL1_HUMAN             Reviewed;         804 AA.
AC   O95294; B7ZKM4; C9JFK5; F8VQX1; Q52M03; Q59H24; Q96CC7;
DE   RecName: Full=RasGAP-activating-like protein 1;
GN   Name=RASAL1; Synonyms=RASAL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RASLC_HUMAN             Reviewed;         266 AA.
AC   Q9NYN1; B2RC29;
DE   RecName: Full=Ras-like protein family member 12;
DE   AltName: Full=Ras-like protein Ris;
GN   Name=RASL12; Synonyms=RIS;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RASL3_HUMAN             Reviewed;        1011 AA.
AC   Q86YV0; Q8N2T9; Q9H735;
DE   RecName: Full=RAS protein activator like-3;
GN   Name=RASAL3;
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RASM_HUMAN              Reviewed;         208 AA.
AC   O14807; B4DIK0; Q86WX8;
DE   RecName: Full=Ras-related protein M-Ras;
DE   AltName: Full=Ras-related protein R-Ras3;
DE   Flags: Precursor;
GN   Name=MRAS; Synonyms=RRAS3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
//
ID   RASN_HUMAN              Reviewed;         189 AA.
AC   P01111; Q14971; Q15104; Q15282;
DE   RecName: Full=GTPase NRas;
DE   AltName: Full=Transforming protein N-Ras;
DE   Flags: Precursor;
GN   Name=NRAS; Synonyms=HRAS1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; TAS:Reactome.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0035022; P:positive regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   RAVR1_HUMAN             Reviewed;         606 AA.
AC   Q8IY67; A6NMU4; Q8IY60; Q8TF24;
DE   RecName: Full=Ribonucleoprotein PTB-binding 1;
DE   AltName: Full=Protein raver-1;
GN   Name=RAVER1; Synonyms=KIAA1978;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RAVR2_HUMAN             Reviewed;         691 AA.
AC   Q9HCJ3; Q6P141; Q9NPV7;
DE   RecName: Full=Ribonucleoprotein PTB-binding 2;
DE   AltName: Full=Protein raver-2;
GN   Name=RAVER2; Synonyms=KIAA1579;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RAX2_HUMAN              Reviewed;         184 AA.
AC   Q96IS3;
DE   RecName: Full=Retina and anterior neural fold homeobox protein 2;
DE   AltName: Full=Q50-type retinal homeobox protein;
DE   AltName: Full=Retina and anterior neural fold homeobox-like protein 1;
GN   Name=RAX2; Synonyms=QRX, RAXL1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RB11A_HUMAN             Reviewed;         216 AA.
AC   P62491; B2R4B6; B4DT13; P24410; Q5TZN9; Q9JLX1;
DE   RecName: Full=Ras-related protein Rab-11A;
DE            Short=Rab-11;
DE   AltName: Full=YL8;
DE   Flags: Precursor;
GN   Name=RAB11A; Synonyms=RAB11;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; NAS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0048227; P:plasma membrane to endosome transport; NAS:UniProtKB.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051223; P:regulation of protein transport; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   RB12B_HUMAN             Reviewed;        1001 AA.
AC   Q8IXT5; A8MYB5;
DE   RecName: Full=RNA-binding protein 12B;
DE   AltName: Full=RNA-binding motif protein 12B;
GN   Name=RBM12B;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RB15B_HUMAN             Reviewed;         890 AA.
AC   Q8NDT2; A4QPG7; Q6QE19; Q9BV96;
DE   RecName: Full=Putative RNA-binding protein 15B;
DE   AltName: Full=One-twenty two protein 3;
DE            Short=HuOTT3;
DE   AltName: Full=RNA-binding motif protein 15B;
GN   Name=RBM15B; Synonyms=OTT3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RB11B_HUMAN             Reviewed;         218 AA.
AC   Q15907; A5YM50; B2R7I4; D6W671; Q2YDT2; Q5U0I1; Q6FHR0; Q6FI42;
AC   Q8NI07;
DE   RecName: Full=Ras-related protein Rab-11B;
DE   AltName: Full=GTP-binding protein YPT3;
DE   Flags: Precursor;
GN   Name=RAB11B; Synonyms=YPT3;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071468; P:cellular response to acidity; IDA:UniProtKB.
DR   GO; GO:0045054; P:constitutive secretory pathway; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0035773; P:insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0032402; P:melanosome transport; ISS:UniProtKB.
DR   GO; GO:0001881; P:receptor recycling; ISS:UniProtKB.
DR   GO; GO:0045055; P:regulated secretory pathway; ISS:UniProtKB.
DR   GO; GO:0044070; P:regulation of anion transport; IMP:UniProtKB.
DR   GO; GO:2001135; P:regulation of endocytic recycling; ISS:UniProtKB.
DR   GO; GO:2000008; P:regulation of protein localization to cell surface; IMP:UniProtKB.
DR   GO; GO:1990126; P:retrograde transport, endosome to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0033572; P:transferrin transport; ISS:UniProtKB.
//
ID   RB22A_HUMAN             Reviewed;         194 AA.
AC   Q9UL26; B3KR86; E1P605; Q8TF12; Q9H4E6;
DE   RecName: Full=Ras-related protein Rab-22A;
DE            Short=Rab-22;
GN   Name=RAB22A; Synonyms=RAB22;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IDA:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IEP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB27A_HUMAN             Reviewed;         221 AA.
AC   P51159; O00195; Q6FI40; Q9UIR9; Q9Y5U3;
DE   RecName: Full=Ras-related protein Rab-27A;
DE            Short=Rab-27;
DE   AltName: Full=GTP-binding protein Ram;
GN   Name=RAB27A; Synonyms=RAB27;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; ISS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043316; P:cytotoxic T cell degranulation; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032402; P:melanosome transport; IEA:Ensembl.
DR   GO; GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0043320; P:natural killer cell degranulation; IEA:Ensembl.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB27B_HUMAN             Reviewed;         218 AA.
AC   O00194; B2RAB0; Q9BZB6;
DE   RecName: Full=Ras-related protein Rab-27B;
DE   AltName: Full=C25KG;
GN   Name=RAB27B;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; ISS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; ISS:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB33B_HUMAN             Reviewed;         229 AA.
AC   Q9H082; B2R987; Q4W5B0;
DE   RecName: Full=Ras-related protein Rab-33B;
GN   Name=RAB33B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:2000785; P:regulation of autophagic vacuole assembly; ISS:UniProtKB.
DR   GO; GO:2000156; P:regulation of retrograde vesicle-mediated transport, Golgi to ER; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB33A_HUMAN             Reviewed;         237 AA.
AC   Q14088; Q5JUZ6; Q92465;
DE   RecName: Full=Ras-related protein Rab-33A;
DE   AltName: Full=Small GTP-binding protein S10;
GN   Name=RAB33A; Synonyms=RABS10;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019882; P:antigen processing and presentation; IMP:UniProt.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB40A_HUMAN             Reviewed;         277 AA.
AC   Q8WXH6; O00407; Q17RQ5; Q6DK06; Q8TF06;
DE   RecName: Full=Ras-related protein Rab-40A;
DE   AltName: Full=SOCS box-containing protein RAR2A;
DE            Short=Protein Rar-2;
DE   Flags: Precursor;
GN   Name=RAB40A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB40C_HUMAN             Reviewed;         281 AA.
AC   Q96S21; A2IDE2; D3DU54; O60795; Q4TT41;
DE   RecName: Full=Ras-related protein Rab-40C;
DE   AltName: Full=Rar-like protein;
DE   AltName: Full=Ras-like protein family member 8C;
DE   AltName: Full=SOCS box-containing protein RAR3;
GN   Name=RAB40C; Synonyms=RARL, RASL8C;
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB40B_HUMAN             Reviewed;         278 AA.
AC   Q12829; Q8WVG3;
DE   RecName: Full=Ras-related protein Rab-40B;
DE   AltName: Full=SOCS box-containing protein RAR;
DE            Short=Protein Rar;
GN   Name=RAB40B; Synonyms=SEC4L;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB40L_HUMAN             Reviewed;         278 AA.
AC   P0C0E4; Q495H3;
DE   RecName: Full=Ras-related protein Rab-40A-like;
DE   AltName: Full=Ras-like GTPase;
GN   Name=RAB40AL; Synonyms=RLGP;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB3GP_HUMAN             Reviewed;         981 AA.
AC   Q15042; A6H8Z3; C9J837; Q659F5; Q8TBB4;
DE   RecName: Full=Rab3 GTPase-activating protein catalytic subunit;
DE   AltName: Full=RAB3 GTPase-activating protein 130 kDa subunit;
DE   AltName: Full=Rab3-GAP p130;
DE            Short=Rab3-GAP;
GN   Name=RAB3GAP1; Synonyms=KIAA0066, RAB3GAP;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:BHF-UCL.
DR   GO; GO:0043010; P:camera-type eye development; IMP:BHF-UCL.
DR   GO; GO:0060325; P:face morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0021854; P:hypothalamus development; IMP:BHF-UCL.
DR   GO; GO:0034389; P:lipid particle organization; IMP:MGI.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:UniProtKB.
//
ID   RB39A_HUMAN             Reviewed;         217 AA.
AC   Q14964; A8KAA4; Q8N6W2;
DE   RecName: Full=Ras-related protein Rab-39A;
DE            Short=Rab-39;
GN   Name=RAB39A; Synonyms=RAB39;
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0090383; P:phagosome acidification; IMP:UniProtKB.
DR   GO; GO:0090385; P:phagosome-lysosome fusion; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RB39B_HUMAN             Reviewed;         213 AA.
AC   Q96DA2; Q5JT79; Q8NEX3;
DE   RecName: Full=Ras-related protein Rab-39B;
GN   Name=RAB39B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0050808; P:synapse organization; ISS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   RB6I2_HUMAN             Reviewed;        1116 AA.
AC   Q8IUD2; A2RU77; A7E295; D3DUP7; D3DUP8; Q6NVK2; Q8IUD3; Q8IUD4;
AC   Q8IUD5; Q8NAS1; Q9NXN5; Q9UIK7; Q9UPS1;
DE   RecName: Full=ELKS/Rab6-interacting/CAST family member 1;
DE            Short=ERC-1;
DE   AltName: Full=Rab6-interacting protein 2;
GN   Name=ERC1; Synonyms=ELKS, KIAA1081, RAB6IP2;
DR   GO; GO:0043522; F:leucine zipper domain binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:Ensembl.
//
ID   RB8NL_HUMAN             Reviewed;         664 AA.
AC   Q8NC74; B2RP98; Q8N4Z9; Q9BR75; Q9H0Y9;
DE   RecName: Full=RBBP8 N-terminal-like protein;
GN   Name=RBBP8NL; Synonyms=C20orf151;
//
ID   RBAK_HUMAN              Reviewed;         714 AA.
AC   Q9NYW8; A6NDF2; A8KAK4; B2RN44; B9EGS1; F8W6M7;
DE   RecName: Full=RB-associated KRAB zinc finger protein;
DE   AltName: Full=RB-associated KRAB repressor;
DE            Short=hRBaK;
DE   AltName: Full=Zinc finger protein 769;
GN   Name=RBAK; Synonyms=ZNF769;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBAS1_HUMAN             Reviewed;         102 AA.
AC   Q9P1G2;
DE   RecName: Full=Putative uncharacterized protein encoded by RBM12B-AS1;
DE   AltName: Full=RBM12B antisense RNA 1;
DE   AltName: Full=RBM12B antisense gene protein 1;
GN   Name=RBM12B-AS1; Synonyms=C8orf39; ORFNames=PRO1905;
//
ID   RBBP4_HUMAN             Reviewed;         425 AA.
AC   Q09028; B2R6G9; B4DRH0; D3DPQ3; P31149; Q53H02; Q96BV9;
DE   RecName: Full=Histone-binding protein RBBP4;
DE   AltName: Full=Chromatin assembly factor 1 subunit C;
DE            Short=CAF-1 subunit C;
DE   AltName: Full=Chromatin assembly factor I p48 subunit;
DE            Short=CAF-I 48 kDa subunit;
DE            Short=CAF-I p48;
DE   AltName: Full=Nucleosome-remodeling factor subunit RBAP48;
DE   AltName: Full=Retinoblastoma-binding protein 4;
DE            Short=RBBP-4;
DE   AltName: Full=Retinoblastoma-binding protein p48;
GN   Name=RBBP4; Synonyms=RBAP48;
DR   GO; GO:0042393; F:histone binding; NAS:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0031497; P:chromatin assembly; IDA:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:HGNC.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006335; P:DNA replication-dependent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBBP6_HUMAN             Reviewed;        1792 AA.
AC   Q7Z6E9; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q8N0V2;
AC   Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4;
DE   RecName: Full=E3 ubiquitin-protein ligase RBBP6;
DE            EC=6.3.2.-;
DE   AltName: Full=Proliferation potential-related protein;
DE   AltName: Full=Protein P2P-R;
DE   AltName: Full=Retinoblastoma-binding Q protein 1;
DE            Short=RBQ-1;
DE   AltName: Full=Retinoblastoma-binding protein 6;
DE   AltName: Full=p53-associated cellular protein of testis;
GN   Name=RBBP6; Synonyms=P2PR, PACT, RBQ1; ORFNames=My038;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0061053; P:somite development; IEA:Ensembl.
//
ID   RBBP7_HUMAN             Reviewed;         425 AA.
AC   Q16576; Q5JP00;
DE   RecName: Full=Histone-binding protein RBBP7;
DE   AltName: Full=Histone acetyltransferase type B subunit 2;
DE   AltName: Full=Nucleosome-remodeling factor subunit RBAP46;
DE   AltName: Full=Retinoblastoma-binding protein 7;
DE            Short=RBBP-7;
DE   AltName: Full=Retinoblastoma-binding protein p46;
GN   Name=RBBP7; Synonyms=RBAP46;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0070370; P:cellular heat acclimation; IDA:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBBP5_HUMAN             Reviewed;         538 AA.
AC   Q15291; A8K272; Q7Z6D8; Q8NDZ7;
DE   RecName: Full=Retinoblastoma-binding protein 5;
DE            Short=RBBP-5;
DE   AltName: Full=Retinoblastoma-binding protein RBQ-3;
GN   Name=RBBP5; Synonyms=RBQ3;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBBP9_HUMAN             Reviewed;         186 AA.
AC   O75884; D3DW31; Q5JPH9; Q9H1D8;
DE   RecName: Full=Putative hydrolase RBBP9;
DE            EC=3.-.-.-;
DE   AltName: Full=B5T-overexpressed gene protein;
DE            Short=Protein BOG;
DE   AltName: Full=Retinoblastoma-binding protein 10;
DE            Short=RBBP-10;
DE   AltName: Full=Retinoblastoma-binding protein 9;
DE            Short=RBBP-9;
GN   Name=RBBP9; Synonyms=BOG, RBBP10;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
//
ID   RBCC1_HUMAN             Reviewed;        1594 AA.
AC   Q8TDY2; Q86YR4; Q8WVU9; Q92601;
DE   RecName: Full=RB1-inducible coiled-coil protein 1;
DE   AltName: Full=FAK family kinase-interacting protein of 200 kDa;
DE            Short=FIP200;
GN   Name=RB1CC1; Synonyms=KIAA0203, RBICC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045793; P:positive regulation of cell size; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0010506; P:regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBFA_HUMAN              Reviewed;         343 AA.
AC   Q8N0V3; Q6PF07; Q8WZ65; Q9H776;
DE   RecName: Full=Putative ribosome-binding factor A, mitochondrial;
DE   Flags: Precursor;
GN   Name=RBFA; Synonyms=C18orf22;
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   RBG10_HUMAN             Reviewed;         253 AA.
AC   B7ZAP0; B7ZAA4;
DE   RecName: Full=Rab GTPase-activating protein 1-like, isoform 10;
GN   Name=RABGAP1L; Synonyms=HHL, KIAA0471;
//
ID   RBG1L_HUMAN             Reviewed;         815 AA.
AC   Q5R372; O75059; Q3ZTR8; Q5R369; Q8IVV0; Q8N921; Q8WV78; Q9NSP8;
AC   Q9UQ19; Q9UQP5; Q9Y6Y5; Q9Y6Y6;
DE   RecName: Full=Rab GTPase-activating protein 1-like;
GN   Name=RABGAP1L; Synonyms=HHL, KIAA0471;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IDA:MGI.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:BHF-UCL.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:MGI.
//
ID   RBGPR_HUMAN             Reviewed;        1393 AA.
AC   Q9H2M9; A6H8V0; O75872; Q9HAB0; Q9UFJ7; Q9UQ15;
DE   RecName: Full=Rab3 GTPase-activating protein non-catalytic subunit;
DE   AltName: Full=RGAP-iso;
DE   AltName: Full=Rab3 GTPase-activating protein 150 kDa subunit;
DE   AltName: Full=Rab3-GAP p150;
DE            Short=Rab3-GAP150;
DE   AltName: Full=Rab3-GAP regulatory subunit;
GN   Name=RAB3GAP2; Synonyms=KIAA0839;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0030234; F:enzyme regulator activity; ISS:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.
//
ID   RBGP1_HUMAN             Reviewed;        1069 AA.
AC   Q9Y3P9; B9A6L2; Q05CW2; Q6ZMY1; Q9HA28; Q9P0E2; Q9UG67;
DE   RecName: Full=Rab GTPase-activating protein 1;
DE   AltName: Full=GAP and centrosome-associated protein;
DE   AltName: Full=Rab6 GTPase-activating protein GAPCenA;
GN   Name=RABGAP1; ORFNames=HSPC094;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0015631; F:tubulin binding; TAS:ProtInc.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
//
ID   RBL1_HUMAN              Reviewed;        1068 AA.
AC   P28749; A8K2W5; Q4VXA0; Q8N5K6; Q9H1L5; Q9H1M1;
DE   RecName: Full=Retinoblastoma-like protein 1;
DE   AltName: Full=107 kDa retinoblastoma-associated protein;
DE            Short=p107;
DE   AltName: Full=pRb1;
GN   Name=RBL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0043550; P:regulation of lipid kinase activity; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RBL2A_HUMAN             Reviewed;         228 AA.
AC   Q9UBK7; B7ZBD6; Q9NU37;
DE   RecName: Full=Rab-like protein 2A;
GN   Name=RABL2A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RBL2B_HUMAN             Reviewed;         228 AA.
AC   Q9UNT1; Q5TZT8; Q96C33;
DE   RecName: Full=Rab-like protein 2B;
GN   Name=RABL2B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RBL2_HUMAN              Reviewed;        1139 AA.
AC   Q08999; B7Z913; Q15073; Q16084; Q8NE70; Q92812;
DE   RecName: Full=Retinoblastoma-like protein 2;
DE   AltName: Full=130 kDa retinoblastoma-associated protein;
DE            Short=p130;
DE   AltName: Full=Retinoblastoma-related protein 2;
DE            Short=RBR-2;
DE   AltName: Full=pRb2;
GN   Name=RBL2; Synonyms=RB2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
DR   GO; GO:0043550; P:regulation of lipid kinase activity; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBM10_HUMAN             Reviewed;         930 AA.
AC   P98175; C4AM81; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1;
DE   RecName: Full=RNA-binding protein 10;
DE   AltName: Full=G patch domain-containing protein 9;
DE   AltName: Full=RNA-binding motif protein 10;
DE   AltName: Full=RNA-binding protein S1-1;
DE            Short=S1-1;
GN   Name=RBM10; Synonyms=DXS8237E, GPATC9, GPATCH9, KIAA0122;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0034393; P:positive regulation of smooth muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM11_HUMAN             Reviewed;         281 AA.
AC   P57052; Q6YNC2; Q8NBA1; Q8NFF6;
DE   RecName: Full=Splicing regulator RBM11;
DE   AltName: Full=RNA-binding motif protein 11;
GN   Name=RBM11;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008266; F:poly(U) RNA binding; IDA:MGI.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:MGI.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:MGI.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM12_HUMAN             Reviewed;         932 AA.
AC   Q9NTZ6; B3KRU2; E1P5R6; O94865; Q8N3B1; Q9H196;
DE   RecName: Full=RNA-binding protein 12;
DE   AltName: Full=RNA-binding motif protein 12;
DE   AltName: Full=SH3/WW domain anchor protein in the nucleus;
DE            Short=SWAN;
GN   Name=RBM12; Synonyms=KIAA0765; ORFNames=HRIHFB2091;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RBM14_HUMAN             Reviewed;         669 AA.
AC   Q96PK6; B0LM41; B3KMN4; D6RGD8; O75932; Q2PYN1; Q53GV1; Q68DQ9;
AC   Q96PK5;
DE   RecName: Full=RNA-binding protein 14;
DE   AltName: Full=Paraspeckle protein 2;
DE            Short=PSP2;
DE   AltName: Full=RNA-binding motif protein 14;
DE   AltName: Full=RRM-containing coactivator activator/modulator;
DE   AltName: Full=Synaptotagmin-interacting protein;
DE            Short=SYT-interacting protein;
GN   Name=RBM14; Synonyms=SIP;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IPI:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; NAS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; NAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0042921; P:glucocorticoid receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; IPI:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; TAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; NAS:GOC.
//
ID   RBM15_HUMAN             Reviewed;         977 AA.
AC   Q96T37; A1A693; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4;
AC   Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0;
DE   RecName: Full=Putative RNA-binding protein 15;
DE   AltName: Full=One-twenty two protein 1;
DE   AltName: Full=RNA-binding motif protein 15;
GN   Name=RBM15; Synonyms=OTT, OTT1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0007221; P:positive regulation of transcription of Notch receptor target; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RBM20_HUMAN             Reviewed;        1227 AA.
AC   Q5T481; A6NIP5; B5A868; Q5JVI1;
DE   RecName: Full=RNA-binding protein 20;
DE   AltName: Full=RNA-binding motif protein 20;
GN   Name=RBM20;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0033120; P:positive regulation of RNA splicing; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM22_HUMAN             Reviewed;         420 AA.
AC   Q9NW64; A6NDM5; B4DLI9; O95607;
DE   RecName: Full=Pre-mRNA-splicing factor RBM22;
DE   AltName: Full=RNA-binding motif protein 22;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 16;
GN   Name=RBM22; Synonyms=ZC3H16; ORFNames=199G4;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.
DR   GO; GO:0017069; F:snRNA binding; IDA:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IDA:UniProtKB.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0033120; P:positive regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
//
ID   RBM18_HUMAN             Reviewed;         190 AA.
AC   Q96H35; B3KQ89;
DE   RecName: Full=Probable RNA-binding protein 18;
DE   AltName: Full=RNA-binding motif protein 18;
GN   Name=RBM18;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBM19_HUMAN             Reviewed;         960 AA.
AC   Q9Y4C8; A8K5X9; Q9BPY6; Q9UFN5;
DE   RecName: Full=Probable RNA-binding protein 19;
DE   AltName: Full=RNA-binding motif protein 19;
GN   Name=RBM19; Synonyms=KIAA0682;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.
//
ID   RBM23_HUMAN             Reviewed;         439 AA.
AC   Q86U06; D3DS32; Q8ND16; Q8TB88; Q8WY40; Q9BUJ1; Q9NVV7;
DE   RecName: Full=Probable RNA-binding protein 23;
DE   AltName: Full=RNA-binding motif protein 23;
DE   AltName: Full=RNA-binding region-containing protein 4;
DE   AltName: Full=Splicing factor SF2;
GN   Name=RBM23; Synonyms=RNPC4; ORFNames=PP239;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
//
ID   RBM24_HUMAN             Reviewed;         236 AA.
AC   Q9BX46; E9PAY4; Q6QDA4; Q8N9D3; Q96NI3;
DE   RecName: Full=RNA-binding protein 24;
DE   AltName: Full=RNA-binding motif protein 24;
DE   AltName: Full=RNA-binding region-containing protein 6;
GN   Name=RBM24; Synonyms=RNPC6;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.
DR   GO; GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.
//
ID   RBM25_HUMAN             Reviewed;         843 AA.
AC   P49756; A0PJL9; B2RNA8; B3KT03; Q2TA72; Q5XJ17; Q6P665; Q9H6A1;
AC   Q9UEQ5; Q9UIE9;
DE   RecName: Full=RNA-binding protein 25;
DE   AltName: Full=Arg/Glu/Asp-rich protein of 120 kDa;
DE            Short=RED120;
DE   AltName: Full=Protein S164;
DE   AltName: Full=RNA-binding motif protein 25;
DE   AltName: Full=RNA-binding region-containing protein 7;
GN   Name=RBM25; Synonyms=RNPC7;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM26_HUMAN             Reviewed;        1007 AA.
AC   Q5T8P6; B4DZE0; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P8; Q5U5P5;
AC   Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7;
DE   RecName: Full=RNA-binding protein 26;
DE   AltName: Full=CTCL tumor antigen se70-2;
DE   AltName: Full=RNA-binding motif protein 26;
GN   Name=RBM26; Synonyms=C13orf10; ORFNames=PRO1777;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   RBM28_HUMAN             Reviewed;         759 AA.
AC   Q9NW13; A4D100; B4DU52; E9PDD9; Q53H65; Q96CV3;
DE   RecName: Full=RNA-binding protein 28;
DE   AltName: Full=RNA-binding motif protein 28;
GN   Name=RBM28;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM33_HUMAN             Reviewed;        1170 AA.
AC   Q96EV2; A4D244; B5MC24; Q52LF5; Q75LN9; Q75ML5; Q9NSV0;
DE   RecName: Full=RNA-binding protein 33;
DE   AltName: Full=Proline-rich protein 8;
DE   AltName: Full=RNA-binding motif protein 33;
GN   Name=RBM33; Synonyms=PRR8;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RBM34_HUMAN             Reviewed;         430 AA.
AC   P42696; A8K8J7; Q8N2Z8; Q9H5A1;
DE   RecName: Full=RNA-binding protein 34;
DE   AltName: Full=RNA-binding motif protein 34;
GN   Name=RBM34; Synonyms=KIAA0117;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RBM38_HUMAN             Reviewed;         239 AA.
AC   Q9H0Z9; A6NDK1; A6NMU6; Q15350; Q15351; Q9BYK3; Q9BYK4;
DE   RecName: Full=RNA-binding protein 38;
DE   AltName: Full=CLL-associated antigen KW-5;
DE   AltName: Full=HSRNASEB;
DE   AltName: Full=RNA-binding motif protein 38;
DE   AltName: Full=RNA-binding region-containing protein 1;
DE   AltName: Full=ssDNA-binding protein SEB4;
GN   Name=RBM38; Synonyms=RNPC1, SEB4;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010830; P:regulation of myotube differentiation; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM39_HUMAN             Reviewed;         530 AA.
AC   Q14498; A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; Q14499;
DE   RecName: Full=RNA-binding protein 39;
DE   AltName: Full=Hepatocellular carcinoma protein 1;
DE   AltName: Full=RNA-binding motif protein 39;
DE   AltName: Full=RNA-binding region-containing protein 2;
DE   AltName: Full=Splicing factor HCC1;
GN   Name=RBM39; Synonyms=HCC1, RNPC2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBM3_HUMAN              Reviewed;         157 AA.
AC   P98179;
DE   RecName: Full=Putative RNA-binding protein 3;
DE   AltName: Full=RNA-binding motif protein 3;
DE   AltName: Full=RNPL;
GN   Name=RBM3; Synonyms=RNPL;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0045727; P:positive regulation of translation; ISS:UniProtKB.
DR   GO; GO:0035196; P:production of miRNAs involved in gene silencing by miRNA; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; IEA:Ensembl.
//
ID   RBM27_HUMAN             Reviewed;        1060 AA.
AC   Q9P2N5; Q8IYW9;
DE   RecName: Full=RNA-binding protein 27;
DE   AltName: Full=RNA-binding motif protein 27;
GN   Name=RBM27; Synonyms=KIAA1311;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
//
ID   RBM40_HUMAN             Reviewed;         517 AA.
AC   Q96LT9; A8K1C9; D3DT74; Q5TZ87; Q96FK7; Q96JI8; Q9NSU7; Q9NXX2;
DE   RecName: Full=RNA-binding protein 40;
DE   AltName: Full=RNA-binding motif protein 40;
DE   AltName: Full=RNA-binding region-containing protein 3;
DE   AltName: Full=U11/U12 small nuclear ribonucleoprotein 65 kDa protein;
DE            Short=U11/U12 snRNP 65 kDa protein;
DE            Short=U11/U12-65K;
GN   Name=RNPC3; Synonyms=KIAA1839, RBM40, RNP;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IC:UniProtKB.
//
ID   RBM41_HUMAN             Reviewed;         413 AA.
AC   Q96IZ5; Q5JSN7; Q5JSN8; Q9H8F7; Q9NV04;
DE   RecName: Full=RNA-binding protein 41;
DE   AltName: Full=RNA-binding motif protein 41;
GN   Name=RBM41;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBM42_HUMAN             Reviewed;         480 AA.
AC   Q9BTD8; O00320; Q8N5R7; Q9BU66;
DE   RecName: Full=RNA-binding protein 42;
DE   AltName: Full=RNA-binding motif protein 42;
GN   Name=RBM42;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RBM43_HUMAN             Reviewed;         357 AA.
AC   Q6ZSC3; B2RMT5;
DE   RecName: Full=RNA-binding protein 43;
DE   AltName: Full=RNA-binding motif protein 43;
GN   Name=RBM43; Synonyms=C2orf38;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBM44_HUMAN             Reviewed;        1051 AA.
AC   Q6ZP01; A0AUW3;
DE   RecName: Full=RNA-binding protein 44;
DE   AltName: Full=RNA-binding motif protein 44;
GN   Name=RBM44;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBM46_HUMAN             Reviewed;         533 AA.
AC   Q8TBY0;
DE   RecName: Full=Probable RNA-binding protein 46;
DE   AltName: Full=Cancer/testis antigen 68;
DE            Short=CT68;
DE   AltName: Full=RNA-binding motif protein 46;
GN   Name=RBM46;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBM47_HUMAN             Reviewed;         593 AA.
AC   A0AV96; A0PJK2; B5MED4; Q8NI52; Q8NI53; Q9NXG3;
DE   RecName: Full=RNA-binding protein 47;
DE   AltName: Full=RNA-binding motif protein 47;
GN   Name=RBM47;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RBM48_HUMAN             Reviewed;         367 AA.
AC   Q5RL73; B7ZL51; Q5H9T2; Q8IYW7; Q96NS0; Q9H0V7;
DE   RecName: Full=RNA-binding protein 48;
GN   Name=RBM48; Synonyms=C7orf64; ORFNames=HSPC304;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBM4B_HUMAN             Reviewed;         359 AA.
AC   Q9BQ04; B3KT83;
DE   RecName: Full=RNA-binding protein 4B;
DE   AltName: Full=RNA-binding motif protein 30;
DE   AltName: Full=RNA-binding motif protein 4B;
DE   AltName: Full=RNA-binding protein 30;
GN   Name=RBM4B; Synonyms=RBM30;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBM45_HUMAN             Reviewed;         476 AA.
AC   Q8IUH3; Q6NYL0; Q8NFC9;
DE   RecName: Full=RNA-binding protein 45;
DE   AltName: Full=Developmentally-regulated RNA-binding protein 1;
DE            Short=RB-1;
DE   AltName: Full=RNA-binding motif protein 45;
GN   Name=RBM45; Synonyms=DRB1, DRBP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
//
ID   RBM4_HUMAN              Reviewed;         364 AA.
AC   Q9BWF3; B3KUN0; B4E1U0; E7EQS3; O02916; Q4VC48; Q6P1P2; Q8WU85;
DE   RecName: Full=RNA-binding protein 4;
DE   AltName: Full=Lark homolog;
DE            Short=hLark;
DE   AltName: Full=RNA-binding motif protein 4;
DE   AltName: Full=RNA-binding motif protein 4a;
GN   Name=RBM4; Synonyms=RBM4A;
DR   GO; GO:0035198; F:miRNA binding; IDA:UniProtKB.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0097157; F:pre-mRNA intronic binding; IDA:UniProtKB.
DR   GO; GO:0097158; F:pre-mRNA intronic pyrimidine-rich binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002190; P:cap-independent translational initiation; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0097167; P:circadian regulation of translation; ISS:UniProtKB.
DR   GO; GO:0043153; P:entrainment of circadian clock by photoperiod; ISS:UniProtKB.
DR   GO; GO:0002192; P:IRES-dependent translational initiation; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0032055; P:negative regulation of translation in response to stress; IDA:UniProtKB.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IDA:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0046822; P:regulation of nucleocytoplasmic transport; IDA:UniProtKB.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; IDA:UniProtKB.
//
ID   RBM5_HUMAN              Reviewed;         815 AA.
AC   P52756; B2RA45; B4DM16; B4DMF9; B4DZ63; Q93021; Q9BU14; Q9HDA6;
AC   Q9UKY8; Q9UL24;
DE   RecName: Full=RNA-binding protein 5;
DE   AltName: Full=Protein G15;
DE   AltName: Full=Putative tumor suppressor LUCA15;
DE   AltName: Full=RNA-binding motif protein 5;
DE   AltName: Full=Renal carcinoma antigen NY-REN-9;
GN   Name=RBM5; ORFNames=H37, LUCA15;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
//
ID   RBM6_HUMAN              Reviewed;        1123 AA.
AC   P78332; O60549; O75524; Q86SS3;
DE   RecName: Full=RNA-binding protein 6;
DE   AltName: Full=Lung cancer antigen NY-LU-12;
DE   AltName: Full=Protein G16;
DE   AltName: Full=RNA-binding motif protein 6;
DE   AltName: Full=RNA-binding protein DEF-3;
GN   Name=RBM6; Synonyms=DEF3;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   RBM7_HUMAN              Reviewed;         266 AA.
AC   Q9Y580; B2R6K8; Q9NUT4;
DE   RecName: Full=RNA-binding protein 7;
DE   AltName: Full=RNA-binding motif protein 7;
GN   Name=RBM7;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   RBM8A_HUMAN             Reviewed;         174 AA.
AC   Q9Y5S9; B3KQI9; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4;
DE   RecName: Full=RNA-binding protein 8A;
DE   AltName: Full=Binder of OVCA1-1;
DE            Short=BOV-1;
DE   AltName: Full=RNA-binding motif protein 8A;
DE   AltName: Full=RNA-binding protein Y14;
DE   AltName: Full=Ribonucleoprotein RBM8A;
GN   Name=RBM8A; Synonyms=RBM8; ORFNames=HSPC114, MDS014;
DR   GO; GO:0003729; F:mRNA binding; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   RBMS1_HUMAN             Reviewed;         406 AA.
AC   P29558; Q14869; Q15433; Q53P46; Q53QX8; Q53RG6; Q8WV20;
DE   RecName: Full=RNA-binding motif, single-stranded-interacting protein 1;
DE   AltName: Full=Single-stranded DNA-binding protein MSSP-1;
DE   AltName: Full=Suppressor of CDC2 with RNA-binding motif 2;
GN   Name=RBMS1; Synonyms=C2orf12, MSSP, MSSP1, SCR2;
DR   GO; GO:0003690; F:double-stranded DNA binding; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   RBMS2_HUMAN             Reviewed;         407 AA.
AC   Q15434;
DE   RecName: Full=RNA-binding motif, single-stranded-interacting protein 2;
DE   AltName: Full=Suppressor of CDC2 with RNA-binding motif 3;
GN   Name=RBMS2; Synonyms=SCR3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
//
ID   RBMS3_HUMAN             Reviewed;         437 AA.
AC   Q6XE24; A8K9S4; B7ZL17; G5E9J9; O75876; Q17RI0; Q6XE23;
DE   RecName: Full=RNA-binding motif, single-stranded-interacting protein 3;
GN   Name=RBMS3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RBMX2_HUMAN             Reviewed;         322 AA.
AC   Q9Y388; A8K9Z0; Q5JY82; Q9Y3I8;
DE   RecName: Full=RNA-binding motif protein, X-linked 2;
GN   Name=RBMX2; ORFNames=CGI-79;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RBMX_HUMAN              Reviewed;         391 AA.
AC   P38159; B4E3U4; D3DWH0; E9PG86; Q5JQ67; Q8N8Y7; Q969R3;
DE   RecName: Full=RNA-binding motif protein, X chromosome;
DE   AltName: Full=Glycoprotein p43;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein G;
DE            Short=hnRNP G;
DE   Contains:
DE     RecName: Full=RNA-binding motif protein, X chromosome, N-terminally processed;
GN   Name=RBMX; Synonyms=HNRPG, RBMXP1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IEA:Ensembl.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   RBNS5_HUMAN             Reviewed;         784 AA.
AC   Q9H1K0; Q3KP30; Q59EY8; Q8NAQ1;
DE   RecName: Full=Rabenosyn-5;
DE   AltName: Full=110 kDa protein;
DE   AltName: Full=FYVE finger-containing Rab5 effector protein rabenosyn-5;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 20;
GN   Name=ZFYVE20;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016197; P:endosomal transport; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RBP17_HUMAN             Reviewed;        1088 AA.
AC   Q9H2T7;
DE   RecName: Full=Ran-binding protein 17;
GN   Name=RANBP17;
DR   GO; GO:0005525; F:GTP binding; NAS:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006606; P:protein import into nucleus; NAS:UniProtKB.
//
ID   RBP10_HUMAN             Reviewed;         620 AA.
AC   Q6VN20; A4FTY2; Q9P264;
DE   RecName: Full=Ran-binding protein 10;
DE            Short=RanBP10;
GN   Name=RANBP10; Synonyms=KIAA1464;
DR   GO; GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
//
ID   RBP1_HUMAN              Reviewed;         655 AA.
AC   Q15311; D3DUI0;
DE   RecName: Full=RalA-binding protein 1;
DE            Short=RalBP1;
DE   AltName: Full=76 kDa Ral-interacting protein;
DE   AltName: Full=Dinitrophenyl S-glutathione ATPase;
DE            Short=DNP-SG ATPase;
DE   AltName: Full=Ral-interacting protein 1;
GN   Name=RALBP1; Synonyms=RLIP1, RLIP76;
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.
DR   GO; GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.
DR   GO; GO:0006810; P:transport; IDA:UniProtKB.
//
ID   RBP2_HUMAN              Reviewed;        3224 AA.
AC   P49792; Q13074; Q15280; Q53TE2; Q59FH7;
DE   RecName: Full=E3 SUMO-protein ligase RanBP2;
DE            EC=6.3.2.-;
DE   AltName: Full=358 kDa nucleoporin;
DE   AltName: Full=Nuclear pore complex protein Nup358;
DE   AltName: Full=Nucleoporin Nup358;
DE   AltName: Full=Ran-binding protein 2;
DE            Short=RanBP2;
DE   AltName: Full=p270;
GN   Name=RANBP2; Synonyms=NUP358;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0033132; P:negative regulation of glucokinase activity; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0090526; P:regulation of gluconeogenesis involved in cellular glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RBP56_HUMAN             Reviewed;         592 AA.
AC   Q92804; B2R837; Q86X94; Q92751;
DE   RecName: Full=TATA-binding protein-associated factor 2N;
DE   AltName: Full=68 kDa TATA-binding protein-associated factor;
DE            Short=TAF(II)68;
DE            Short=TAFII68;
DE   AltName: Full=RNA-binding protein 56;
GN   Name=TAF15; Synonyms=RBP56, TAF2N;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
//
ID   RBPJL_HUMAN             Reviewed;         517 AA.
AC   Q9UBG7; O95723; Q5QPU9; Q5QPV0; Q9ULV9;
DE   RecName: Full=Recombining binding protein suppressor of hairless-like protein;
DE   AltName: Full=Transcription factor RBP-L;
GN   Name=RBPJL; Synonyms=RBPL, RBPSUHL;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RBPMS_HUMAN             Reviewed;         196 AA.
AC   Q93062; D3DSU9; Q92516; Q92517; Q92518; Q96J26;
DE   RecName: Full=RNA-binding protein with multiple splicing;
DE            Short=RBP-MS;
DE   AltName: Full=Heart and RRM expressed sequence;
DE            Short=Hermes;
GN   Name=RBPMS; Synonyms=HERMES;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RBPS2_HUMAN             Reviewed;         209 AA.
AC   Q6ZRY4;
DE   RecName: Full=RNA-binding protein with multiple splicing 2;
GN   Name=RBPMS2;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   RBSK_HUMAN              Reviewed;         322 AA.
AC   Q9H477; A9UK04; B4DV96;
DE   RecName: Full=Ribokinase;
DE            EC=2.7.1.15;
GN   Name=RBKS; Synonyms=RBSK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004747; F:ribokinase activity; IEA:InterPro.
DR   GO; GO:0019303; P:D-ribose catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006014; P:D-ribose metabolic process; IEA:InterPro.
//
ID   RBTN1_HUMAN             Reviewed;         156 AA.
AC   P25800; E9PSF5; Q4VBC5; Q8IXR0;
DE   RecName: Full=Rhombotin-1;
DE   AltName: Full=Cysteine-rich protein TTG-1;
DE   AltName: Full=LIM domain only protein 1;
DE            Short=LMO-1;
DE   AltName: Full=T-cell translocation protein 1;
GN   Name=LMO1; Synonyms=RBTN1, RHOM1, TTG1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
//
ID   RBTN2_HUMAN             Reviewed;         158 AA.
AC   P25791; Q9HD58;
DE   RecName: Full=Rhombotin-2;
DE   AltName: Full=Cysteine-rich protein TTG-2;
DE   AltName: Full=LIM domain only protein 2;
DE            Short=LMO-2;
DE   AltName: Full=T-cell translocation protein 2;
GN   Name=LMO2; Synonyms=RBTN2, RBTNL1, RHOM2, TTG2;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0048037; F:cofactor binding; IPI:BHF-UCL.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   RBX1_HUMAN              Reviewed;         108 AA.
AC   P62877; B2RDY1; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254;
DE   RecName: Full=E3 ubiquitin-protein ligase RBX1;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein ZYP;
DE   AltName: Full=RING finger protein 75;
DE   AltName: Full=RING-box protein 1;
DE            Short=Rbx1;
DE   AltName: Full=Regulator of cullins 1;
DE   Contains:
DE     RecName: Full=E3 ubiquitin-protein ligase RBX1, N-terminally processed;
GN   Name=RBX1; Synonyms=RNF75, ROC1;
DR   GO; GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0045116; P:protein neddylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RBX2_HUMAN              Reviewed;         113 AA.
AC   Q9UBF6; A8K1H9; A8MTB5; C9JYL3; D3DNF7; D3DNF8; Q9BXN8; Q9Y5M7;
DE   RecName: Full=RING-box protein 2;
DE            Short=Rbx2;
DE   AltName: Full=CKII beta-binding protein 1;
DE            Short=CKBBP1;
DE   AltName: Full=RING finger protein 7;
DE   AltName: Full=Regulator of cullins 2;
DE   AltName: Full=Sensitive to apoptosis gene protein;
GN   Name=RNF7; Synonyms=RBX2, ROC2, SAG;
DR   GO; GO:0005507; F:copper ion binding; TAS:ProtInc.
DR   GO; GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0045116; P:protein neddylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0051775; P:response to redox state; TAS:ProtInc.
//
ID   RBY1A_HUMAN             Reviewed;         496 AA.
AC   P0DJD3; Q15376; Q15377; Q15414; Q6NSB5; Q86VU6; Q8NHR0;
DE   RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member A1;
DE   AltName: Full=RNA-binding motif protein 1;
DE   AltName: Full=RNA-binding motif protein 2;
DE   AltName: Full=Y chromosome RNA recognition motif 1;
DE            Short=hRBMY;
GN   Name=RBMY1A1; Synonyms=RBM1, RBM2, YRRM1, YRRM2;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBY1B_HUMAN             Reviewed;         496 AA.
AC   A6NDE4; A6NCZ8; A6NE80; A8MSJ6;
DE   RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member B;
GN   Name=RBMY1B;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:UniProtKB.
//
ID   RBY1C_HUMAN             Reviewed;         496 AA.
AC   P0DJD4; Q15376; Q15377; Q15414; Q6NSB5; Q86VU6; Q8NHR0;
DE   RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member C;
GN   Name=RBMY1C;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBY1D_HUMAN             Reviewed;         496 AA.
AC   P0C7P1;
DE   RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member D;
GN   Name=RBMY1D;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBY1E_HUMAN             Reviewed;         496 AA.
AC   A6NEQ0; A6NCW6; A6NEG9; A6NKQ5;
DE   RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member E;
GN   Name=RBMY1E;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RBY1F_HUMAN             Reviewed;         496 AA.
AC   Q15415; B2R916;
DE   RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member F/J;
DE   AltName: Full=Y chromosome RNA recognition motif 2;
GN   Name=RBMY1F; Synonyms=YRRM2;
GN   and
GN   Name=RBMY1J;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   RB_HUMAN                Reviewed;         928 AA.
AC   P06400; A8K5E3; P78499; Q5VW46; Q8IZL4;
DE   RecName: Full=Retinoblastoma-associated protein;
DE   AltName: Full=p105-Rb;
DE   AltName: Full=pRb;
DE            Short=Rb;
DE   AltName: Full=pp110;
GN   Name=RB1;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IDA:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:BHF-UCL.
DR   GO; GO:0000075; P:cell cycle checkpoint; TAS:ProtInc.
DR   GO; GO:0048667; P:cell morphogenesis involved in neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034349; P:glial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; TAS:BHF-UCL.
DR   GO; GO:0045445; P:myoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; TAS:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IPI:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; TAS:BHF-UCL.
DR   GO; GO:0071930; P:negative regulation of transcription involved in G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0071459; P:protein localization to chromosome, centromeric region; IMP:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.
DR   GO; GO:0090230; P:regulation of centromere complex assembly; TAS:BHF-UCL.
DR   GO; GO:0071922; P:regulation of cohesin localization to chromatin; IMP:BHF-UCL.
DR   GO; GO:0043550; P:regulation of lipid kinase activity; IDA:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:BHF-UCL.
DR   GO; GO:0031134; P:sister chromatid biorientation; IMP:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0051146; P:striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RC3H1_HUMAN             Reviewed;        1133 AA.
AC   Q5TC82; B3KVK1; Q5W180; Q5W181; Q8IVE6; Q8N9V1;
DE   RecName: Full=Roquin-1;
DE            Short=Roquin;
DE   AltName: Full=RING finger and C3H zinc finger protein 1;
DE   AltName: Full=RING finger and CCCH-type zinc finger domain-containing protein 1;
DE   AltName: Full=RING finger protein 198;
GN   Name=RC3H1; Synonyms=KIAA2025, RNF198;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; ISS:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033962; P:cytoplasmic mRNA processing body assembly; ISS:BHF-UCL.
DR   GO; GO:0046007; P:negative regulation of activated T cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0002635; P:negative regulation of germinal center formation; ISS:BHF-UCL.
DR   GO; GO:0045623; P:negative regulation of T-helper cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; ISS:BHF-UCL.
DR   GO; GO:0010608; P:posttranscriptional regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:GOC.
DR   GO; GO:0002634; P:regulation of germinal center formation; ISS:BHF-UCL.
DR   GO; GO:0043488; P:regulation of mRNA stability; ISS:BHF-UCL.
DR   GO; GO:0050856; P:regulation of T cell receptor signaling pathway; ISS:BHF-UCL.
//
ID   RC3H2_HUMAN             Reviewed;        1191 AA.
AC   Q9HBD1; Q4VXB1; Q5JPD7; Q86ST6; Q8N3D6; Q96F27; Q9H5J2; Q9HBD2;
AC   Q9NWN9; Q9NXE1;
DE   RecName: Full=Roquin-2;
DE   AltName: Full=Membrane-associated nucleic acid-binding protein;
DE   AltName: Full=RING finger and CCCH-type zinc finger domain-containing protein 2;
DE   AltName: Full=RING finger protein 164;
GN   Name=RC3H2; Synonyms=MNAB, RNF164;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000209; P:protein polyubiquitination; IMP:FlyBase.
//
ID   RCAN1_HUMAN             Reviewed;         252 AA.
AC   P53805; D3DSF9; O00582; O00583; Q53XT0; Q6IBC6; Q7Z555; Q96R03;
AC   Q9BU69; Q9UF15; Q9UME4;
DE   RecName: Full=Calcipressin-1;
DE   AltName: Full=Adapt78;
DE   AltName: Full=Down syndrome critical region protein 1;
DE   AltName: Full=Myocyte-enriched calcineurin-interacting protein 1;
DE            Short=MCIP1;
DE   AltName: Full=Regulator of calcineurin 1;
GN   Name=RCAN1; Synonyms=ADAPT78, CSP1, DSC1, DSCR1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0051151; P:negative regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
//
ID   RCAN2_HUMAN             Reviewed;         197 AA.
AC   Q14206; A6ND07; B3KR46; Q5VWF7; Q5VWF8; Q8N116;
DE   RecName: Full=Calcipressin-2;
DE   AltName: Full=Down syndrome candidate region 1-like 1;
DE   AltName: Full=Myocyte-enriched calcineurin-interacting protein 2;
DE            Short=MCIP2;
DE   AltName: Full=Regulator of calcineurin 2;
DE   AltName: Full=Thyroid hormone-responsive protein ZAKI-4;
GN   Name=RCAN2; Synonyms=DSCR1L1, ZAKI4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:InterPro.
//
ID   RCAN3_HUMAN             Reviewed;         241 AA.
AC   Q9UKA8; A4GU14; A4LA69; E3VWE2; E5L4P0; E5L4P7; E7ENV1; E7EWD8;
AC   G1FI66; G1FLF0; Q5ECL3; Q5TGC6; Q9NUC8; Q9UKA7;
DE   RecName: Full=Calcipressin-3;
DE   AltName: Full=Down syndrome candidate region 1-like protein 2;
DE   AltName: Full=Myocyte-enriched calcineurin-interacting protein 3;
DE            Short=MCIP3;
DE   AltName: Full=Regulator of calcineurin 3;
GN   Name=RCAN3; Synonyms=DSCR1L2;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0031013; F:troponin I binding; IPI:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:InterPro.
//
ID   RCAS1_HUMAN             Reviewed;         213 AA.
AC   O00559; Q6IB20; Q9BS76;
DE   RecName: Full=Receptor-binding cancer antigen expressed on SiSo cells;
DE   AltName: Full=Cancer-associated surface antigen RCAS1;
DE   AltName: Full=Estrogen receptor-binding fragment-associated gene 9 protein;
GN   Name=EBAG9; Synonyms=RCAS1;
DR   GO; GO:0016505; F:peptidase activator activity involved in apoptotic process; NAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   RCBT1_HUMAN             Reviewed;         531 AA.
AC   Q8NDN9; Q8IY29; Q969U9;
DE   RecName: Full=RCC1 and BTB domain-containing protein 1;
DE   AltName: Full=Chronic lymphocytic leukemia deletion region gene 7 protein;
DE            Short=CLL deletion region gene 7 protein;
DE   AltName: Full=Regulator of chromosome condensation and BTB domain-containing protein 1;
GN   Name=RCBTB1; Synonyms=CLLD7, E4.5;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RCBT2_HUMAN             Reviewed;         551 AA.
AC   O95199; B2RDW8;
DE   RecName: Full=RCC1 and BTB domain-containing protein 2;
DE   AltName: Full=Chromosome condensation 1-like;
DE            Short=CHC1-L;
DE   AltName: Full=RCC1-like G exchanging factor;
DE   AltName: Full=Regulator of chromosome condensation and BTB domain-containing protein 2;
GN   Name=RCBTB2; Synonyms=CHC1L, RLG;
DR   GO; GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0032316; P:regulation of Ran GTPase activity; TAS:GOC.
//
ID   RCC1_HUMAN              Reviewed;         421 AA.
AC   P18754; Q16269; Q6NT97;
DE   RecName: Full=Regulator of chromosome condensation;
DE   AltName: Full=Cell cycle regulatory protein;
DE   AltName: Full=Chromosome condensation protein 1;
GN   Name=RCC1; Synonyms=CHC1;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.
DR   GO; GO:0007088; P:regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0032316; P:regulation of Ran GTPase activity; IDA:GOC.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RCCD1_HUMAN             Reviewed;         376 AA.
AC   A6NED2; B2RTP9; Q29RX6;
DE   RecName: Full=RCC1 domain-containing protein 1;
GN   Name=RCCD1;
//
ID   RCC2_HUMAN              Reviewed;         522 AA.
AC   Q9P258; Q8IVL9; Q9BSN6; Q9NPV8;
DE   RecName: Full=Protein RCC2;
DE   AltName: Full=RCC1-like protein TD-60;
DE   AltName: Full=Telophase disk protein of 60 kDa;
GN   Name=RCC2; Synonyms=KIAA1470, TD60;
DR   GO; GO:0008017; F:microtubule binding; IMP:UniProt.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0048041; P:focal adhesion assembly; IDA:UniProt.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProt.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; ISS:UniProt.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; ISS:UniProt.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; ISS:UniProt.
DR   GO; GO:0051987; P:positive regulation of attachment of spindle microtubules to kinetochore; IMP:UniProt.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:UniProt.
DR   GO; GO:0030334; P:regulation of cell migration; ISS:UniProt.
//
ID   RCD1_HUMAN              Reviewed;         299 AA.
AC   Q92600; B2RPI0; B7Z1E5; Q96IX4;
DE   RecName: Full=Cell differentiation protein RCD1 homolog;
DE            Short=Rcd-1;
DE   AltName: Full=CCR4-NOT transcription complex subunit 9;
GN   Name=RQCD1; Synonyms=CNOT9, RCD1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:2000327; P:positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007548; P:sex differentiation; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RCL1_HUMAN              Reviewed;         373 AA.
AC   Q9Y2P8; D3DRI2; Q5VYW9; Q9H9D0; Q9NY00; Q9P044;
DE   RecName: Full=RNA 3'-terminal phosphate cyclase-like protein;
GN   Name=RCL1; Synonyms=RNAC, RPC2, RPCL1, RTC2; ORFNames=HSPC338;
DR   GO; GO:0003963; F:RNA-3'-phosphate cyclase activity; NAS:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   RCN1_HUMAN              Reviewed;         331 AA.
AC   Q15293; D3DR00;
DE   RecName: Full=Reticulocalbin-1;
DE   Flags: Precursor;
GN   Name=RCN1; Synonyms=RCN;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
//
ID   RCN2_HUMAN              Reviewed;         317 AA.
AC   Q14257; A8MTG6; Q53XN8;
DE   RecName: Full=Reticulocalbin-2;
DE   AltName: Full=Calcium-binding protein ERC-55;
DE   AltName: Full=E6-binding protein;
DE            Short=E6BP;
DE   Flags: Precursor;
GN   Name=RCN2; Synonyms=ERC55;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RCN3_HUMAN              Reviewed;         328 AA.
AC   Q96D15; Q9HBZ8;
DE   RecName: Full=Reticulocalbin-3;
DE   AltName: Full=EF-hand calcium-binding protein RLP49;
DE   Flags: Precursor;
GN   Name=RCN3; ORFNames=UNQ239/PRO272;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RCOR1_HUMAN             Reviewed;         482 AA.
AC   Q9UKL0; Q15044; Q6P2I9; Q86VG5;
DE   RecName: Full=REST corepressor 1;
DE   AltName: Full=Protein CoREST;
GN   Name=RCOR1; Synonyms=KIAA0071, RCOR;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RCOR2_HUMAN             Reviewed;         523 AA.
AC   Q8IZ40; Q96FP3;
DE   RecName: Full=REST corepressor 2;
GN   Name=RCOR2;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RCOR3_HUMAN             Reviewed;         495 AA.
AC   Q9P2K3; B3KYA2; B4DYY7; Q5VT47; Q7L9I5; Q8N5U3; Q9NV83;
DE   RecName: Full=REST corepressor 3;
GN   Name=RCOR3; Synonyms=KIAA1343;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RD21L_HUMAN             Reviewed;         556 AA.
AC   Q9H4I0; B2RXL0; B7ZBB1; B7ZW76; Q5W0X5;
DE   RecName: Full=Double-strand-break repair protein rad21-like protein 1;
GN   Name=RAD21L1; Synonyms=RAD21L;
DR   GO; GO:0070197; P:attachment of telomeric heterochromatin to nuclear envelope; IEA:Ensembl.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0030999; P:linear element assembly; IEA:Ensembl.
DR   GO; GO:0007128; P:meiotic prophase I; ISS:UniProtKB.
DR   GO; GO:0072520; P:seminiferous tubule development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   RD23A_HUMAN             Reviewed;         363 AA.
AC   P54725; K7ESE3; Q59EU8; Q5M7Z1;
DE   RecName: Full=UV excision repair protein RAD23 homolog A;
DE            Short=HR23A;
DE            Short=hHR23A;
GN   Name=RAD23A;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RD23B_HUMAN             Reviewed;         409 AA.
AC   P54727; B3KWK8; G5E9P0; Q7Z5K8; Q8WUB0;
DE   RecName: Full=UV excision repair protein RAD23 homolog B;
DE            Short=HR23B;
DE            Short=hHR23B;
DE   AltName: Full=XP-C repair-complementing complex 58 kDa protein;
DE            Short=p58;
GN   Name=RAD23B;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.
DR   GO; GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:UniProtKB.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   RD3_HUMAN               Reviewed;         195 AA.
AC   Q7Z3Z2; A8K595;
DE   RecName: Full=Protein RD3;
DE   AltName: Full=Retinal degeneration protein 3;
GN   Name=RD3; Synonyms=C1orf36;
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RD3L_HUMAN              Reviewed;         198 AA.
AC   P0DJH9;
DE   RecName: Full=Protein RD3-like;
DE   AltName: Full=Retinal degeneration protein 3-like;
GN   Name=RD3L;
//
ID   RDH11_HUMAN             Reviewed;         318 AA.
AC   Q8TC12; A6NDK3; A8K062; B2RB26; B4DDW0; Q0QD40; Q6IAH5; Q9NRW0;
AC   Q9Y391;
DE   RecName: Full=Retinol dehydrogenase 11;
DE            EC=1.1.1.300;
DE   AltName: Full=Androgen-regulated short-chain dehydrogenase/reductase 1;
DE   AltName: Full=HCV core-binding protein HCBP12;
DE   AltName: Full=Prostate short-chain dehydrogenase/reductase 1;
DE   AltName: Full=Retinal reductase 1;
DE            Short=RalR1;
GN   Name=RDH11; Synonyms=ARSDR1, PSDR1; ORFNames=CGI-82;
DR   GO; GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.
DR   GO; GO:0016062; P:adaptation of rhodopsin mediated signaling; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:MGI.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; ISS:UniProtKB.
//
ID   RDH10_HUMAN             Reviewed;         341 AA.
AC   Q8IZV5;
DE   RecName: Full=Retinol dehydrogenase 10;
DE            EC=1.1.1.300;
GN   Name=RDH10; ORFNames=UNQ9375/PRO34191;
DR   GO; GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0060449; P:bud elongation involved in lung branching; IEA:Ensembl.
DR   GO; GO:0043583; P:ear development; IEA:Ensembl.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0008406; P:gonad development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0043584; P:nose development; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0060431; P:primary lung bud formation; IEA:Ensembl.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:UniProtKB.
DR   GO; GO:0002138; P:retinoic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; IDA:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IDA:MGI.
//
ID   RDH13_HUMAN             Reviewed;         331 AA.
AC   Q8NBN7; Q6UX79; Q96G88;
DE   RecName: Full=Retinol dehydrogenase 13;
DE            EC=1.1.1.-;
GN   Name=RDH13; ORFNames=PSEC0082, UNQ736/PRO1430;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   RDH12_HUMAN             Reviewed;         316 AA.
AC   Q96NR8; B2RDA2; Q8TAW6;
DE   RecName: Full=Retinol dehydrogenase 12;
DE            EC=1.1.1.-;
DE   AltName: Full=All-trans and 9-cis retinol dehydrogenase;
GN   Name=RDH12;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; TAS:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; IDA:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:UniProtKB.
//
ID   RDH14_HUMAN             Reviewed;         336 AA.
AC   Q9HBH5;
DE   RecName: Full=Retinol dehydrogenase 14;
DE            EC=1.1.1.-;
DE   AltName: Full=Alcohol dehydrogenase PAN2;
GN   Name=RDH14; Synonyms=PAN2; ORFNames=UNQ529/PRO1072;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   RDH16_HUMAN             Reviewed;         317 AA.
AC   O75452; Q9UNV2;
DE   RecName: Full=Retinol dehydrogenase 16;
DE            EC=1.1.-.-;
DE   AltName: Full=Microsomal NAD(+)-dependent retinol dehydrogenase 4;
DE            Short=RoDH-4;
DE   AltName: Full=Sterol/retinol dehydrogenase;
GN   Name=RDH16; Synonyms=RODH4;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
//
ID   RDH1_HUMAN              Reviewed;         318 AA.
AC   Q92781; O00179; Q8TAI2;
DE   RecName: Full=11-cis retinol dehydrogenase;
DE            Short=11-cis RDH;
DE            Short=11-cis RoDH;
DE            EC=1.1.1.315;
DE   AltName: Full=9-cis retinol dehydrogenase;
DE            Short=9cRDH;
DE   Flags: Precursor;
GN   Name=RDH5; Synonyms=RDH1;
DR   GO; GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RDH8_HUMAN              Reviewed;         311 AA.
AC   Q9NYR8; Q9H838;
DE   RecName: Full=Retinol dehydrogenase 8;
DE            EC=1.1.1.300;
DE   AltName: Full=Photoreceptor outer segment all-trans retinol dehydrogenase;
GN   Name=RDH8; Synonyms=PRRDH;
DR   GO; GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc.
DR   GO; GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RDHE2_HUMAN             Reviewed;         309 AA.
AC   Q8N3Y7; B4DGK2; Q330K3; Q8TDV9; Q96LX1;
DE   RecName: Full=Epidermal retinol dehydrogenase 2;
DE            Short=EPHD-2;
DE            Short=RDH-E2;
DE            EC=1.1.1.105;
DE   AltName: Full=Retinal short-chain dehydrogenase reductase 2;
DE            Short=retSDR2;
DE   AltName: Full=Short-chain dehydrogenase/reductase family 16C member 5;
GN   Name=SDR16C5; Synonyms=RDHE2;
DR   GO; GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; NAS:UniProtKB.
DR   GO; GO:0043616; P:keratinocyte proliferation; IMP:UniProtKB.
DR   GO; GO:0042574; P:retinal metabolic process; IDA:UniProtKB.
DR   GO; GO:0042572; P:retinol metabolic process; IDA:UniProtKB.
//
ID   RDM1_HUMAN              Reviewed;         284 AA.
AC   Q8NG50; A0JP55; A8MV46; A8MY68; A8MZ92; A8RCS5; A8RCT0; A8RCT5;
AC   A8RCT8; A8RCU3; A8RCU8; A8RCW0; A8RCW5;
DE   RecName: Full=RAD52 motif-containing protein 1;
DE   AltName: Full=RAD52 homolog B;
GN   Name=RDM1; Synonyms=RAD52B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
//
ID   REBL1_HUMAN             Reviewed;         183 AA.
AC   Q8TAI7; Q56VH8;
DE   RecName: Full=GTPase RhebL1;
DE   AltName: Full=Ras homolog enriched in brain like-1 c;
DE            Short=RhebL1c;
DE   AltName: Full=Ras homolog enriched in brain-like protein 1;
DE            Short=Rheb-like protein 1;
DE   AltName: Full=Rheb2;
DE   Flags: Precursor;
GN   Name=RHEBL1;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0031929; P:TOR signaling; IMP:UniProtKB.
//
ID   REC16_HUMAN             Reviewed;         105 AA.
AC   P61578;
DE   RecName: Full=HERV-K_10p14 provirus Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC1_HUMAN              Reviewed;         104 AA.
AC   P61571;
DE   RecName: Full=HERV-K_12q14.1 provirus Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC17_HUMAN             Reviewed;         105 AA.
AC   P61579; Q53Z28;
DE   RecName: Full=HERV-K_11q22.1 provirus Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC2_HUMAN              Reviewed;         105 AA.
AC   Q69383;
DE   RecName: Full=HERV-K_7q22.1 provirus Rec protein;
DE   AltName: Full=Central open reading frame;
DE            Short=c-orf;
DE            Short=cORF;
DE   AltName: Full=Endogenous retrovirus K protein 6;
DE   AltName: Full=HERV-K(C7) Rec protein;
DE   AltName: Full=HERV-K(HML-2.HOM) Rec protein;
DE   AltName: Full=HERV-K108 Rec protein;
DE   AltName: Full=K-Rev;
DE   AltName: Full=Rev-like protein;
DE   AltName: Full=Rev/Rex homolog;
GN   Name=ERVK-6; Synonyms=ERVK6;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC5_HUMAN              Reviewed;         105 AA.
AC   P61574;
DE   RecName: Full=HERV-K_19p13.11 provirus Rec protein;
DE   AltName: Full=HERV-K113 Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC3_HUMAN              Reviewed;         105 AA.
AC   P61572;
DE   RecName: Full=HERV-K_19q12 provirus Rec protein;
DE   AltName: Full=HERV-K(C19) Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC6_HUMAN              Reviewed;         105 AA.
AC   P61575;
DE   RecName: Full=HERV-K_8p23.1 provirus Rec protein;
DE   AltName: Full=HERV-K115 Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC8_HUMAN              Reviewed;         547 AA.
AC   O95072; A8K576; D3DS62; Q658V5; Q6IA92; Q8WUV8; Q9BTF2; Q9NVQ9;
DE   RecName: Full=Meiotic recombination protein REC8 homolog;
DE   AltName: Full=Cohesin Rec8p;
GN   Name=REC8; Synonyms=REC8L1;
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0030999; P:linear element assembly; IEA:Ensembl.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0072520; P:seminiferous tubule development; IEA:Ensembl.
DR   GO; GO:0007062; P:sister chromatid cohesion; TAS:ProtInc.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   REC4_HUMAN              Reviewed;         105 AA.
AC   P61573;
DE   RecName: Full=HERV-K_6q14.1 provirus Rec protein;
DE   AltName: Full=HERV-K(C6) Rec protein;
DE   AltName: Full=HERV-K109 Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   REC9_HUMAN              Reviewed;         105 AA.
AC   P61576;
DE   RecName: Full=HERV-K_5q13.3 provirus Rec protein;
DE   AltName: Full=HERV-K104 Rec protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
//
ID   RECK_HUMAN              Reviewed;         971 AA.
AC   O95980; B2RNS1; Q5W0K6; Q8WX37;
DE   RecName: Full=Reversion-inducing cysteine-rich protein with Kazal motifs;
DE            Short=hRECK;
DE   AltName: Full=Suppressor of tumorigenicity 15 protein;
DE   Flags: Precursor;
GN   Name=RECK; Synonyms=ST15;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IDA:MGI.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001955; P:blood vessel maturation; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:GOC.
//
ID   RECO_HUMAN              Reviewed;         200 AA.
AC   P35243; Q53XL0;
DE   RecName: Full=Recoverin;
DE   AltName: Full=Cancer-associated retinopathy protein;
DE            Short=Protein CAR;
GN   Name=RCVRN; Synonyms=RCV1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0008048; F:calcium sensitive guanylate cyclase activator activity; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0031284; P:positive regulation of guanylate cyclase activity; TAS:GOC.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RECQ1_HUMAN             Reviewed;         649 AA.
AC   P46063; A8K6G2;
DE   RecName: Full=ATP-dependent DNA helicase Q1;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA helicase, RecQ-like type 1;
DE            Short=RecQ1;
DE   AltName: Full=DNA-dependent ATPase Q1;
DE   AltName: Full=RecQ protein-like 1;
GN   Name=RECQL; Synonyms=RECQ1, RECQL1;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:UniProtKB.
//
ID   RECQ5_HUMAN             Reviewed;         991 AA.
AC   O94762; Q9H0B1; Q9P1W7; Q9UNC8;
DE   RecName: Full=ATP-dependent DNA helicase Q5;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA helicase, RecQ-like type 5;
DE            Short=RecQ5;
DE   AltName: Full=RecQ protein-like 5;
GN   Name=RECQL5; Synonyms=RECQ5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0051304; P:chromosome separation; IMP:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006259; P:DNA metabolic process; NAS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   RECQ4_HUMAN             Reviewed;        1208 AA.
AC   O94761; Q3Y424; Q96DW2; Q96F55;
DE   RecName: Full=ATP-dependent DNA helicase Q4;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA helicase, RecQ-like type 4;
DE            Short=RecQ4;
DE   AltName: Full=RTS;
DE   AltName: Full=RecQ protein-like 4;
GN   Name=RECQL4; Synonyms=RECQ4;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IMP:UniProtKB.
DR   GO; GO:0000405; F:bubble DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   RED1_HUMAN              Reviewed;         741 AA.
AC   P78563; A6NFK8; A6NJ84; C3TTQ1; C3TTQ2; C9JUP4; G5E9B4; O00395;
AC   O00465; O00691; O00692; P78555; Q4AE79; Q6P0M9; Q8NFD1;
DE   RecName: Full=Double-stranded RNA-specific editase 1;
DE            EC=3.5.4.37;
DE   AltName: Full=RNA-editing deaminase 1;
DE   AltName: Full=RNA-editing enzyme 1;
DE   AltName: Full=dsRNA adenosine deaminase;
GN   Name=ADARB1; Synonyms=ADAR2, DRADA2, RED1;
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IDA:HGNC.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; TAS:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006382; P:adenosine to inosine editing; IEA:Ensembl.
DR   GO; GO:0016553; P:base conversion or substitution editing; IC:HGNC.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0016556; P:mRNA modification; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0044387; P:negative regulation of protein kinase activity by regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   RED2_HUMAN              Reviewed;         739 AA.
AC   Q9NS39; B2RPJ5; Q5VUT6;
DE   RecName: Full=Double-stranded RNA-specific editase B2;
DE            EC=3.5.-.-;
DE   AltName: Full=RNA-dependent adenosine deaminase 3;
DE   AltName: Full=RNA-editing deaminase 2;
DE   AltName: Full=RNA-editing enzyme 2;
DE   AltName: Full=dsRNA adenosine deaminase B2;
GN   Name=ADARB2; Synonyms=ADAR3, RED2;
DR   GO; GO:0004000; F:adenosine deaminase activity; TAS:ProtInc.
DR   GO; GO:0003725; F:double-stranded RNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
//
ID   RED_HUMAN               Reviewed;         557 AA.
AC   Q13123; Q6IPD8;
DE   RecName: Full=Protein Red;
DE   AltName: Full=Cytokine IK;
DE   AltName: Full=IK factor;
DE   AltName: Full=Protein RER;
GN   Name=IK; Synonyms=RED, RER;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
//
ID   REEP1_HUMAN             Reviewed;         201 AA.
AC   Q9H902; B7Z4D7; B7Z4F2; B7Z5R9; D6W5M2; Q53TI0;
DE   RecName: Full=Receptor expression-enhancing protein 1;
GN   Name=REEP1; Synonyms=C2orf23;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0031849; F:olfactory receptor binding; IMP:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IMP:UniProtKB.
DR   GO; GO:0051205; P:protein insertion into membrane; IDA:HGNC.
//
ID   REEP2_HUMAN             Reviewed;         252 AA.
AC   Q9BRK0; Q53EM8; Q9NYF2;
DE   RecName: Full=Receptor expression-enhancing protein 2;
GN   Name=REEP2; Synonyms=C5orf19, SGC32445;
DR   GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IMP:UniProtKB.
DR   GO; GO:0032596; P:protein transport into membrane raft; IEA:Ensembl.
DR   GO; GO:0050913; P:sensory perception of bitter taste; IEA:Ensembl.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IEA:Ensembl.
//
ID   REEP3_HUMAN             Reviewed;         255 AA.
AC   Q6NUK4; Q5JQR5; Q5QGT2; Q6PEW8; Q6PJY4;
DE   RecName: Full=Receptor expression-enhancing protein 3;
GN   Name=REEP3; Synonyms=C10orf74;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; IMP:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; IMP:UniProtKB.
//
ID   REEP4_HUMAN             Reviewed;         257 AA.
AC   Q9H6H4; D3DSQ9; Q86VL1; Q9H6I5; Q9HBP4;
DE   RecName: Full=Receptor expression-enhancing protein 4;
GN   Name=REEP4; Synonyms=C8orf20; ORFNames=PP432;
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; IMP:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; IMP:UniProtKB.
//
ID   REEP5_HUMAN             Reviewed;         189 AA.
AC   Q00765; D3DT04; Q04198; Q5QGT0; Q9BWH9;
DE   RecName: Full=Receptor expression-enhancing protein 5;
DE   AltName: Full=Polyposis locus protein 1;
DE   AltName: Full=Protein TB2;
GN   Name=REEP5; Synonyms=C5orf18, DP1, TB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   REEP6_HUMAN             Reviewed;         184 AA.
AC   Q96HR9; B2RE01; D6W5Z0; Q96LM0;
DE   RecName: Full=Receptor expression-enhancing protein 6;
DE   AltName: Full=Polyposis locus protein 1-like 1;
GN   Name=REEP6; Synonyms=C19orf32, DP1L1;
//
ID   REG1B_HUMAN             Reviewed;         166 AA.
AC   P48304;
DE   RecName: Full=Lithostathine-1-beta;
DE   AltName: Full=Pancreatic stone protein 2;
DE            Short=PSP-2;
DE   AltName: Full=Regenerating islet-derived protein 1-beta;
DE            Short=REG-1-beta;
DE   AltName: Full=Regenerating protein I beta;
DE   Flags: Precursor;
GN   Name=REG1B; Synonyms=PSPS2, REGL;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
//
ID   REG1A_HUMAN             Reviewed;         166 AA.
AC   P05451; P11379; Q4ZG28;
DE   RecName: Full=Lithostathine-1-alpha;
DE   AltName: Full=Islet cells regeneration factor;
DE            Short=ICRF;
DE   AltName: Full=Islet of Langerhans regenerating protein;
DE            Short=REG;
DE   AltName: Full=Pancreatic stone protein;
DE            Short=PSP;
DE   AltName: Full=Pancreatic thread protein;
DE            Short=PTP;
DE   AltName: Full=Regenerating islet-derived protein 1-alpha;
DE            Short=REG-1-alpha;
DE   AltName: Full=Regenerating protein I alpha;
DE   Flags: Precursor;
GN   Name=REG1A; Synonyms=PSPS, PSPS1, REG;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008083; F:growth factor activity; IDA:MGI.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   REG3A_HUMAN             Reviewed;         175 AA.
AC   Q06141;
DE   RecName: Full=Regenerating islet-derived protein 3-alpha;
DE            Short=REG-3-alpha;
DE   AltName: Full=Hepatointestinal pancreatic protein;
DE            Short=HIP/PAP;
DE   AltName: Full=Human proislet peptide;
DE   AltName: Full=Pancreatitis-associated protein 1;
DE   AltName: Full=Regenerating islet-derived protein III-alpha;
DE            Short=Reg III-alpha;
DE   Contains:
DE     RecName: Full=Regenerating islet-derived protein 3-alpha 16.5 kDa form;
DE   Contains:
DE     RecName: Full=Regenerating islet-derived protein 3-alpha 15 kDa form;
DE   Flags: Precursor;
GN   Name=REG3A; Synonyms=HIP, PAP, PAP1;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.
//
ID   REG3G_HUMAN             Reviewed;         175 AA.
AC   Q6UW15; A8K980; D6W5J6; Q3SYE4; Q3SYE6; Q6FH18;
DE   RecName: Full=Regenerating islet-derived protein 3-gamma;
DE            Short=REG-3-gamma;
DE   AltName: Full=Pancreatitis-associated protein 1B;
DE            Short=PAP-1B;
DE   AltName: Full=Pancreatitis-associated protein IB;
DE            Short=PAP IB;
DE   AltName: Full=Regenerating islet-derived protein III-gamma;
DE            Short=REG III;
DE            Short=Reg III-gamma;
DE   Contains:
DE     RecName: Full=Regenerating islet-derived protein 3-gamma 16.5 kDa form;
DE   Contains:
DE     RecName: Full=Regenerating islet-derived protein 3-gamma 15 kDa form;
DE   Flags: Precursor;
GN   Name=REG3G; Synonyms=PAP1B; ORFNames=UNQ429/PRO162;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; ISS:UniProtKB.
DR   GO; GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.
//
ID   REG4_HUMAN              Reviewed;         158 AA.
AC   Q9BYZ8; Q8NER6; Q8NER7;
DE   RecName: Full=Regenerating islet-derived protein 4;
DE            Short=REG-4;
DE   AltName: Full=Gastrointestinal secretory protein;
DE   AltName: Full=REG-like protein;
DE   AltName: Full=Regenerating islet-derived protein IV;
DE            Short=Reg IV;
DE   Flags: Precursor;
GN   Name=REG4; Synonyms=GISP, RELP;
DR   GO; GO:0008201; F:heparin binding; IDA:UniProt.
DR   GO; GO:2001065; F:mannan binding; IDA:UniProt.
//
ID   REL1_HUMAN              Reviewed;         185 AA.
AC   P04808; Q99936; Q9UQJ1;
DE   RecName: Full=Prorelaxin H1;
DE   Contains:
DE     RecName: Full=Relaxin B chain;
DE   Contains:
DE     RecName: Full=Relaxin A chain;
DE   Flags: Precursor;
GN   Name=RLN1;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; NAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   REL2_HUMAN              Reviewed;         185 AA.
AC   P04090; A0AVM0; Q99936; Q9UCX3; Q9UQJ2;
DE   RecName: Full=Prorelaxin H2;
DE   Contains:
DE     RecName: Full=Relaxin B chain;
DE   Contains:
DE     RecName: Full=Relaxin A chain;
DE   Flags: Precursor;
GN   Name=RLN2;
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
//
ID   REL3_HUMAN              Reviewed;         142 AA.
AC   Q8WXF3; Q6UXW5;
DE   RecName: Full=Relaxin-3;
DE   AltName: Full=Insulin-like peptide INSL7;
DE            Short=Insulin-like peptide 7;
DE   AltName: Full=Prorelaxin H3;
DE   Contains:
DE     RecName: Full=Relaxin-3 B chain;
DE   Contains:
DE     RecName: Full=Relaxin-3 A chain;
DE   Flags: Precursor;
GN   Name=RLN3; Synonyms=INSL7, RXN3, ZINS4; ORFNames=UNQ6188/PRO20213;
//
ID   RELB_HUMAN              Reviewed;         579 AA.
AC   Q01201; Q6GTX7; Q9UEI7;
DE   RecName: Full=Transcription factor RelB;
DE   AltName: Full=I-Rel;
GN   Name=RELB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:Ensembl.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045063; P:T-helper 1 cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RELL1_HUMAN             Reviewed;         271 AA.
AC   Q8IUW5; Q8NBK1;
DE   RecName: Full=RELT-like protein 1;
DE   Flags: Precursor;
GN   Name=RELL1; ORFNames=PSEC0162;
//
ID   RELL2_HUMAN             Reviewed;         303 AA.
AC   Q8NC24; D3DQE2; Q6P4E7; Q6UXY2;
DE   RecName: Full=RELT-like protein 2;
GN   Name=RELL2; Synonyms=C5orf16; ORFNames=UNQ9423/PRO34565;
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   RELN_HUMAN              Reviewed;        3460 AA.
AC   P78509; A4D0P9; A4D0Q0; Q86UJ0; Q86UJ8; Q8NDV0; Q9UDQ2;
DE   RecName: Full=Reelin;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=RELN;
DR   GO; GO:0070325; F:lipoprotein particle receptor binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; ISS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0070326; F:very-low-density lipoprotein particle receptor binding; ISS:BHF-UCL.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0000904; P:cell morphogenesis involved in differentiation; ISS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0021800; P:cerebral cortex tangential migration; ISS:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0010001; P:glial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0021766; P:hippocampus development; ISS:BHF-UCL.
DR   GO; GO:0097477; P:lateral motor column neuron migration; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0097114; P:N-methyl-D-aspartate receptor clustering; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:1902078; P:positive regulation of lateral motor column neuron migration; IEA:Ensembl.
DR   GO; GO:1900273; P:positive regulation of long-term synaptic potentiation; ISS:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; ISS:BHF-UCL.
DR   GO; GO:0051057; P:positive regulation of small GTPase mediated signal transduction; ISS:UniProtKB.
DR   GO; GO:0090129; P:positive regulation of synapse maturation; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IEA:Ensembl.
DR   GO; GO:0097119; P:postsynaptic density protein 95 clustering; IEA:Ensembl.
DR   GO; GO:0097120; P:receptor localization to synapse; IEA:Ensembl.
DR   GO; GO:0038026; P:reelin-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0050795; P:regulation of behavior; ISS:BHF-UCL.
DR   GO; GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0050804; P:regulation of synaptic transmission; ISS:BHF-UCL.
DR   GO; GO:0048265; P:response to pain; ISS:UniProtKB.
DR   GO; GO:0021511; P:spinal cord patterning; ISS:UniProtKB.
DR   GO; GO:0021517; P:ventral spinal cord development; IEA:Ensembl.
//
ID   REL_HUMAN               Reviewed;         619 AA.
AC   Q04864; Q2PNZ7; Q6LDY0;
DE   RecName: Full=Proto-oncogene c-Rel;
GN   Name=REL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   REM1_HUMAN              Reviewed;         298 AA.
AC   O75628; E1P5L1; Q5TZR7; Q5TZR8; Q9NP57;
DE   RecName: Full=GTP-binding protein REM 1;
DE   AltName: Full=GTPase-regulating endothelial cell sprouting;
DE   AltName: Full=Rad and Gem-like GTP-binding protein 1;
GN   Name=REM1; Synonyms=GES, REM;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   REM2_HUMAN              Reviewed;         340 AA.
AC   Q8IYK8; Q8N8R8;
DE   RecName: Full=GTP-binding protein REM 2;
DE   AltName: Full=Rad and Gem-like GTP-binding protein 2;
GN   Name=REM2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   REN3A_HUMAN             Reviewed;         476 AA.
AC   Q9H1J1; A2A366; Q5T8C3; Q5T8C9; Q7Z6N3; Q86YK1; Q9BZI8;
DE   RecName: Full=Regulator of nonsense transcripts 3A;
DE   AltName: Full=Nonsense mRNA reducing factor 3A;
DE   AltName: Full=Up-frameshift suppressor 3 homolog A;
DE            Short=hUpf3;
GN   Name=UPF3A; Synonyms=RENT3A, UPF3;
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; NAS:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; NAS:GOC.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   REN3B_HUMAN             Reviewed;         483 AA.
AC   Q9BZI7; D3DWI3; D3DWI4; Q0VAK8; Q9H1J0;
DE   RecName: Full=Regulator of nonsense transcripts 3B;
DE   AltName: Full=Nonsense mRNA reducing factor 3B;
DE   AltName: Full=Up-frameshift suppressor 3 homolog B;
DE            Short=hUpf3B;
DE   AltName: Full=Up-frameshift suppressor 3 homolog on chromosome X;
DE            Short=hUpf3p-X;
GN   Name=UPF3B; Synonyms=RENT3B, UPF3X;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; NAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   RENBP_HUMAN             Reviewed;         427 AA.
AC   P51606; B4DNZ3; Q96BI6;
DE   RecName: Full=N-acylglucosamine 2-epimerase;
DE            Short=AGE;
DE            EC=5.1.3.8;
DE   AltName: Full=GlcNAc 2-epimerase;
DE   AltName: Full=N-acetyl-D-glucosamine 2-epimerase;
DE   AltName: Full=Renin-binding protein;
DE            Short=RnBP;
GN   Name=RENBP;
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0050121; F:N-acylglucosamine 2-epimerase activity; ISS:UniProtKB.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:Ensembl.
DR   GO; GO:0006051; P:N-acetylmannosamine metabolic process; IEA:Ensembl.
DR   GO; GO:0019262; P:N-acetylneuraminate catabolic process; TAS:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
//
ID   RENI_HUMAN              Reviewed;         406 AA.
AC   P00797; Q6FI38; Q6T5C2;
DE   RecName: Full=Renin;
DE            EC=3.4.23.15;
DE   AltName: Full=Angiotensinogenase;
DE   Flags: Precursor;
GN   Name=REN;
DR   GuidetoPHARMACOLOGY; 2413; -.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IDA:HGNC.
DR   GO; GO:0008233; F:peptidase activity; IDA:HGNC.
DR   GO; GO:0005102; F:receptor binding; IPI:HGNC.
DR   GO; GO:0002003; P:angiotensin maturation; IDA:HGNC.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0042756; P:drinking behavior; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IDA:HGNC.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IDA:HGNC.
DR   GO; GO:0002018; P:renin-angiotensin regulation of aldosterone production; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0070305; P:response to cGMP; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
//
ID   RENR_HUMAN              Reviewed;         350 AA.
AC   O75787; Q5QTQ7; Q6T7F5; Q8NBP3; Q8NG15; Q96FV6; Q96LB5; Q9H2P8;
AC   Q9UG89;
DE   RecName: Full=Renin receptor;
DE   AltName: Full=ATPase H(+)-transporting lysosomal accessory protein 2;
DE   AltName: Full=ATPase H(+)-transporting lysosomal-interacting protein 2;
DE   AltName: Full=ER-localized type I transmembrane adaptor;
DE   AltName: Full=Embryonic liver differentiation factor 10;
DE   AltName: Full=N14F;
DE   AltName: Full=Renin/prorenin receptor;
DE   AltName: Full=Vacuolar ATP synthase membrane sector-associated protein M8-9;
DE            Short=ATP6M8-9;
DE            Short=V-ATPase M8.9 subunit;
DE   Flags: Precursor;
GN   Name=ATP6AP2; Synonyms=ATP6IP2, CAPER, ELDF10;
GN   ORFNames=HT028, MSTP009, PSEC0072;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; EXP:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0002003; P:angiotensin maturation; IDA:HGNC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032914; P:positive regulation of transforming growth factor beta1 production; IDA:HGNC.
DR   GO; GO:0006508; P:proteolysis; EXP:GOC.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IDA:HGNC.
//
ID   RENT1_HUMAN             Reviewed;        1129 AA.
AC   Q92900; O00239; O43343; Q86Z25; Q92842;
DE   RecName: Full=Regulator of nonsense transcripts 1;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase RENT1;
DE   AltName: Full=Nonsense mRNA reducing factor 1;
DE            Short=NORF1;
DE   AltName: Full=Up-frameshift suppressor 1 homolog;
DE            Short=hUpf1;
GN   Name=UPF1; Synonyms=KIAA0221, RENT1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IDA:HGNC.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; IDA:HGNC.
DR   GO; GO:0006260; P:DNA replication; IMP:HGNC.
DR   GO; GO:0009048; P:dosage compensation by inactivation of X chromosome; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:HGNC.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProt.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0006449; P:regulation of translational termination; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   RENT2_HUMAN             Reviewed;        1272 AA.
AC   Q9HAU5; A6NLJ5; D3DRS0; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9NWL1;
AC   Q9P2D9; Q9Y4M9;
DE   RecName: Full=Regulator of nonsense transcripts 2;
DE   AltName: Full=Nonsense mRNA reducing factor 2;
DE   AltName: Full=Up-frameshift suppressor 2 homolog;
DE            Short=hUpf2;
GN   Name=UPF2; Synonyms=KIAA1408, RENT2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:HGNC.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   REP15_HUMAN             Reviewed;         236 AA.
AC   Q6BDI9; B2RU16;
DE   RecName: Full=Rab15 effector protein;
GN   Name=REP15;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0001881; P:receptor recycling; IMP:UniProt.
DR   GO; GO:0033572; P:transferrin transport; IDA:UniProt.
//
ID   REPI1_HUMAN             Reviewed;         567 AA.
AC   Q9BWE0; C9J3L7; D3DWZ1; Q7LE03; Q9BUZ6; Q9NZH2; Q9UMP5;
DE   RecName: Full=Replication initiator 1;
DE   AltName: Full=60 kDa origin-specific DNA-binding protein;
DE   AltName: Full=60 kDa replication initiation region protein;
DE   AltName: Full=ATT-binding protein;
DE   AltName: Full=DHFR oribeta-binding protein RIP60;
DE   AltName: Full=Zinc finger protein 464;
GN   Name=REPIN1; Synonyms=RIP60, ZNF464;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
//
ID   REPS1_HUMAN             Reviewed;         796 AA.
AC   Q96D71; B7ZBZ8; B7ZBZ9; B7ZC00; J3KP76; Q5JWJ5; Q5JWJ6; Q5JWJ7;
AC   Q8NDR7; Q8WU62; Q9BXY9;
DE   RecName: Full=RalBP1-associated Eps domain-containing protein 1;
DE   AltName: Full=RalBP1-interacting protein 1;
GN   Name=REPS1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
//
ID   REPS2_HUMAN             Reviewed;         660 AA.
AC   Q8NFH8; A6PWZ6; O43428; Q5JNZ8; Q8NFI5;
DE   RecName: Full=RalBP1-associated Eps domain-containing protein 2;
DE   AltName: Full=Partner of RalBP1;
DE   AltName: Full=RalBP1-interacting protein 2;
GN   Name=REPS2; Synonyms=POB1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   REQU_HUMAN              Reviewed;         391 AA.
AC   Q92785; A8K7C9;
DE   RecName: Full=Zinc finger protein ubi-d4;
DE   AltName: Full=Apoptosis response zinc finger protein;
DE   AltName: Full=BRG1-associated factor 45D;
DE            Short=BAF45D;
DE   AltName: Full=D4, zinc and double PHD fingers family 2;
DE   AltName: Full=Protein requiem;
GN   Name=DPF2; Synonyms=BAF45D, REQ, UBID4;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RER1_HUMAN              Reviewed;         196 AA.
AC   O15258; O95322;
DE   RecName: Full=Protein RER1;
GN   Name=RER1;
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IDA:UniProtKB.
//
ID   RERE_HUMAN              Reviewed;        1566 AA.
AC   Q9P2R6; O43393; O75046; O75359; Q5VXL9; Q6P6B9; Q9Y2W4;
DE   RecName: Full=Arginine-glutamic acid dipeptide repeats protein;
DE   AltName: Full=Atrophin-1-like protein;
DE   AltName: Full=Atrophin-1-related protein;
GN   Name=RERE; Synonyms=ARG, ARP, ATN1L, KIAA0458;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0008267; F:poly-glutamine tract binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RERGL_HUMAN             Reviewed;         205 AA.
AC   Q9H628;
DE   RecName: Full=Ras-related and estrogen-regulated growth inhibitor-like protein;
DE   AltName: Full=RERG/Ras-like protein;
GN   Name=RERGL;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RERG_HUMAN              Reviewed;         199 AA.
AC   Q96A58; B2R9R0; B4DI02;
DE   RecName: Full=Ras-related and estrogen-regulated growth inhibitor;
GN   Name=RERG;
DR   GO; GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.
DR   GO; GO:0019003; F:GDP binding; TAS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
//
ID   RES18_HUMAN             Reviewed;         173 AA.
AC   Q5W5W9; A8MQ49; Q38I23; Q5W5X0;
DE   RecName: Full=Regulated endocrine-specific protein 18;
DE   Contains:
DE     RecName: Full=Regulated endocrine-specific protein 18;
DE   Contains:
DE     RecName: Full=Triskadecapeptide;
DE   Flags: Precursor;
GN   Name=RESP18;
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
//
ID   REST_HUMAN              Reviewed;        1097 AA.
AC   Q13127; A2RUE0; B9EGJ0; Q12956; Q12957; Q13134; Q59ER1; Q8IWI3;
DE   RecName: Full=RE1-silencing transcription factor;
DE   AltName: Full=Neural-restrictive silencer factor;
DE   AltName: Full=X2 box repressor;
GN   Name=REST; Synonyms=NRSF, XBR;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0015271; F:outward rectifier potassium channel activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0060379; P:cardiac muscle cell myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IMP:UniProtKB.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IMP:UniProtKB.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IDA:UniProtKB.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:UniProtKB.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0032348; P:negative regulation of aldosterone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:2000798; P:negative regulation of amniotic stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:2000065; P:negative regulation of cortisol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:2000706; P:negative regulation of dense core granule biogenesis; ISS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.
DR   GO; GO:2000740; P:negative regulation of mesenchymal stem cell differentiation; IMP:UniProtKB.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IMP:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   RET1G_HUMAN             Reviewed;         334 AA.
AC   Q6H3X3; Q6H3X2;
DE   RecName: Full=Retinoic acid early transcript 1G protein;
DE   Flags: Precursor;
GN   Name=RAET1G;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IPI:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IDA:UniProtKB.
//
ID   RET1_HUMAN              Reviewed;         135 AA.
AC   P09455; A8K2Q0; B7Z7A0; E7EWV0; F2Z2F2; Q6FGX8;
DE   RecName: Full=Retinol-binding protein 1;
DE   AltName: Full=Cellular retinol-binding protein;
DE            Short=CRBP;
DE   AltName: Full=Cellular retinol-binding protein I;
DE            Short=CRBP-I;
GN   Name=RBP1; Synonyms=CRBP1;
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0005501; F:retinoid binding; TAS:ProtInc.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0006776; P:vitamin A metabolic process; TAS:ProtInc.
//
ID   RET1L_HUMAN             Reviewed;         246 AA.
AC   Q5VY80; A3KME4; Q8TE74;
DE   RecName: Full=Retinoic acid early transcript 1L protein;
DE   Flags: Precursor;
GN   Name=RAET1L;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0046703; F:natural killer cell lectin-like receptor binding; IBA:RefGenome.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IBA:RefGenome.
//
ID   RET2_HUMAN              Reviewed;         134 AA.
AC   P50120; A8K7G3; Q6ISQ9; Q6ISS7;
DE   RecName: Full=Retinol-binding protein 2;
DE   AltName: Full=Cellular retinol-binding protein II;
DE            Short=CRBP-II;
GN   Name=RBP2; Synonyms=CRBP2;
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0005501; F:retinoid binding; TAS:ProtInc.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0006776; P:vitamin A metabolic process; TAS:ProtInc.
//
ID   RET3_HUMAN              Reviewed;        1247 AA.
AC   P10745; Q0QD34; Q5VSR0; Q8IXN0;
DE   RecName: Full=Retinol-binding protein 3;
DE   AltName: Full=Interphotoreceptor retinoid-binding protein;
DE            Short=IRBP;
DE   AltName: Full=Interstitial retinol-binding protein;
DE   Flags: Precursor;
GN   Name=RBP3;
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0005501; F:retinoid binding; TAS:ProtInc.
DR   GO; GO:0019841; F:retinol binding; IEA:Ensembl.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RET4_HUMAN              Reviewed;         201 AA.
AC   P02753; D3DR38; O43478; O43479; Q5VY24; Q8WWA3; Q9P178;
DE   RecName: Full=Retinol-binding protein 4;
DE   AltName: Full=Plasma retinol-binding protein;
DE            Short=PRBP;
DE            Short=RBP;
DE   Contains:
DE     RecName: Full=Plasma retinol-binding protein(1-182);
DE   Contains:
DE     RecName: Full=Plasma retinol-binding protein(1-181);
DE   Contains:
DE     RecName: Full=Plasma retinol-binding protein(1-179);
DE   Contains:
DE     RecName: Full=Plasma retinol-binding protein(1-176);
DE   Flags: Precursor;
GN   Name=RBP4; ORFNames=PRO2222;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0019841; F:retinol binding; IDA:BHF-UCL.
DR   GO; GO:0034632; F:retinol transporter activity; IC:BHF-UCL.
DR   GO; GO:0048738; P:cardiac muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR   GO; GO:0048562; P:embryonic organ morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060059; P:embryonic retina morphogenesis in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0048706; P:embryonic skeletal system development; ISS:BHF-UCL.
DR   GO; GO:0001654; P:eye development; IMP:BHF-UCL.
DR   GO; GO:0048807; P:female genitalia morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0006094; P:gluconeogenesis; IMP:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IDA:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0060347; P:heart trabecula formation; ISS:BHF-UCL.
DR   GO; GO:0030324; P:lung development; ISS:BHF-UCL.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IDA:BHF-UCL.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; ISS:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
DR   GO; GO:0042574; P:retinal metabolic process; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; IMP:BHF-UCL.
DR   GO; GO:0034633; P:retinol transport; IC:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0060157; P:urinary bladder development; ISS:BHF-UCL.
DR   GO; GO:0060065; P:uterus development; ISS:BHF-UCL.
DR   GO; GO:0060068; P:vagina development; ISS:BHF-UCL.
//
ID   RET5_HUMAN              Reviewed;         135 AA.
AC   P82980; Q53FB1;
DE   RecName: Full=Retinol-binding protein 5;
DE   AltName: Full=Cellular retinol-binding protein III;
DE            Short=CRBP-III;
DE   AltName: Full=HRBPiso;
GN   Name=RBP5;
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0005501; F:retinoid binding; TAS:UniProtKB.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   RETNB_HUMAN             Reviewed;         111 AA.
AC   Q9BQ08; Q14D27;
DE   RecName: Full=Resistin-like beta;
DE   AltName: Full=Colon and small intestine-specific cysteine-rich protein;
DE   AltName: Full=Colon carcinoma-related gene protein;
DE   AltName: Full=Cysteine-rich secreted protein A12-alpha-like 1;
DE   AltName: Full=Cysteine-rich secreted protein FIZZ2;
DE   AltName: Full=RELMbeta;
DE   Flags: Precursor;
GN   Name=RETNLB; Synonyms=CCRG, FIZZ2, HXCP2, RETNL2;
GN   ORFNames=UNQ408/PRO770;
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
//
ID   RETN_HUMAN              Reviewed;         108 AA.
AC   Q9HD89; D6W649; Q540D9;
DE   RecName: Full=Resistin;
DE   AltName: Full=Adipose tissue-specific secretory factor;
DE            Short=ADSF;
DE   AltName: Full=C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein;
DE   AltName: Full=Cysteine-rich secreted protein A12-alpha-like 2;
DE   AltName: Full=Cysteine-rich secreted protein FIZZ3;
DE   Flags: Precursor;
GN   Name=RETN; Synonyms=FIZZ3, HXCP1, RSTN; ORFNames=UNQ407/PRO1199;
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0010714; P:positive regulation of collagen metabolic process; IEA:Ensembl.
DR   GO; GO:2000872; P:positive regulation of progesterone secretion; IEA:Ensembl.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
//
ID   RET7_HUMAN              Reviewed;         134 AA.
AC   Q96R05; B2R517; Q5SWJ4;
DE   RecName: Full=Retinoid-binding protein 7;
DE   AltName: Full=Cellular retinoic acid-binding protein 4;
DE            Short=CRABP4;
DE            Short=CRBP4;
DE   AltName: Full=Cellular retinoic acid-binding protein IV;
DE            Short=CRABP-IV;
GN   Name=RBP7;
DR   GO; GO:0016918; F:retinal binding; IEA:UniProtKB-KW.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   RETST_HUMAN             Reviewed;         610 AA.
AC   Q6NUM9; A6NIK3; Q53R95; Q53SA9; Q6UX05; Q8N2H5; Q96FA4; Q9NXE5;
DE   RecName: Full=All-trans-retinol 13,14-reductase;
DE            EC=1.3.99.23;
DE   AltName: Full=All-trans-13,14-dihydroretinol saturase;
DE            Short=RetSat;
DE   AltName: Full=PPAR-alpha-regulated and starvation-induced gene protein;
DE   Flags: Precursor;
GN   Name=RETSAT; Synonyms=PPSIG; ORFNames=UNQ439/PRO872;
DR   GO; GO:0051786; F:all-trans-retinol 13,14-reductase activity; ISS:HGNC.
DR   GO; GO:0016491; F:oxidoreductase activity; ISS:HGNC.
DR   GO; GO:0055114; P:oxidation-reduction process; ISS:HGNC.
DR   GO; GO:0042572; P:retinol metabolic process; ISS:HGNC.
//
ID   RET_HUMAN               Reviewed;        1114 AA.
AC   P07949; A8K6Z2; Q15250; Q9BTB0; Q9H4A2;
DE   RecName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret;
DE            EC=2.7.10.1;
DE   AltName: Full=Cadherin family member 12;
DE   AltName: Full=Proto-oncogene c-Ret;
DE   Contains:
DE     RecName: Full=Soluble RET kinase fragment;
DE   Contains:
DE     RecName: Full=Extracellular cell-membrane anchored RET cadherin 120 kDa fragment;
DE   Flags: Precursor;
GN   Name=RET; Synonyms=CDHF12, CDHR16, PTC, RET51;
DR   GuidetoPHARMACOLOGY; 2185; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0001838; P:embryonic epithelial tube formation; IEA:Ensembl.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:Ensembl.
DR   GO; GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0097021; P:lymphocyte migration into lymphoid organs; ISS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0061146; P:Peyer's patch morphogenesis; ISS:UniProtKB.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0045793; P:positive regulation of cell size; IEA:Ensembl.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
DR   GO; GO:0072300; P:positive regulation of metanephric glomerulus development; ISS:UniProtKB.
DR   GO; GO:0014042; P:positive regulation of neuron maturation; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007497; P:posterior midgut development; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0050770; P:regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; ISS:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
DR   GO; GO:0035799; P:ureter maturation; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   REV1_HUMAN              Reviewed;        1251 AA.
AC   Q9UBZ9; O95941; Q53SI7; Q9C0J4; Q9NUP2;
DE   RecName: Full=DNA repair protein REV1;
DE            EC=2.7.7.-;
DE   AltName: Full=Alpha integrin-binding protein 80;
DE            Short=AIBP80;
DE   AltName: Full=Rev1-like terminal deoxycytidyl transferase;
GN   Name=REV1; Synonyms=REV1L;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0017125; F:deoxycytidyl transferase activity; IEA:Ensembl.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; TAS:Reactome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:GOC.
DR   GO; GO:0042276; P:error-prone translesion synthesis; TAS:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
//
ID   REXO1_HUMAN             Reviewed;        1221 AA.
AC   Q8N1G1; Q9ULT2;
DE   RecName: Full=RNA exonuclease 1 homolog;
DE            EC=3.1.-.-;
DE   AltName: Full=Elongin-A-binding protein 1;
DE            Short=EloA-BP1;
DE   AltName: Full=Transcription elongation factor B polypeptide 3-binding protein 1;
GN   Name=REXO1; Synonyms=ELOABP1, KIAA1138, TCEB3BP1;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   REXO4_HUMAN             Reviewed;         422 AA.
AC   Q9GZR2; B2RAT2; Q5T8S4; Q5T8S5; Q5T8S6; Q9GZW3;
DE   RecName: Full=RNA exonuclease 4;
DE            EC=3.1.-.-;
DE   AltName: Full=Exonuclease XPMC2;
DE   AltName: Full=Prevents mitotic catastrophe 2 protein homolog;
DE            Short=hPMC2;
GN   Name=REXO4; Synonyms=PMC2, XPMC2H;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   REXON_HUMAN             Reviewed;         774 AA.
AC   Q96IC2; B2RB19; O60364; Q96MB1; Q9BXH9; Q9H0K2; Q9NSM2;
DE   RecName: Full=Putative RNA exonuclease NEF-sp;
DE            EC=3.1.-.-;
GN   ORFNames=44M2.3;
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RF1ML_HUMAN             Reviewed;         380 AA.
AC   Q9UGC7; B3KTA0; Q3KR06; Q5TF44; Q5TF50; Q96CC5; Q96EX4; Q96K40;
DE   RecName: Full=Peptide chain release factor 1-like, mitochondrial;
DE   AltName: Full=Mitochondrial translational release factor 1-like;
DE   AltName: Full=mtRF1a;
DE   Flags: Precursor;
GN   Name=MTRF1L; Synonyms=MTRF1A;
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
//
ID   RF1M_HUMAN              Reviewed;         445 AA.
AC   O75570; Q5T6Y5; Q8IUQ6;
DE   RecName: Full=Peptide chain release factor 1, mitochondrial;
DE            Short=MRF-1;
DE            Short=MtRF-1;
DE   Flags: Precursor;
GN   Name=MTRF1;
DR   GO; GO:0003747; F:translation release factor activity; TAS:ProtInc.
DR   GO; GO:0016149; F:translation release factor activity, codon specific; IEA:InterPro.
DR   GO; GO:0006449; P:regulation of translational termination; TAS:ProtInc.
//
ID   RFA1_HUMAN              Reviewed;         616 AA.
AC   P27694; A8K0Y9; Q59ES9;
DE   RecName: Full=Replication protein A 70 kDa DNA-binding subunit;
DE            Short=RP-A p70;
DE   AltName: Full=Replication factor A protein 1;
DE            Short=RF-A protein 1;
DE   AltName: Full=Single-stranded DNA-binding protein;
DE   Contains:
DE     RecName: Full=Replication protein A 70 kDa DNA-binding subunit, N-terminally processed;
GN   Name=RPA1; Synonyms=REPA1, RPA70;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0000730; P:DNA recombinase assembly; TAS:Reactome.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFA2_HUMAN              Reviewed;         270 AA.
AC   P15927; Q52II0; Q5TEI9; Q5TEJ5;
DE   RecName: Full=Replication protein A 32 kDa subunit;
DE            Short=RP-A p32;
DE   AltName: Full=Replication factor A protein 2;
DE            Short=RF-A protein 2;
DE   AltName: Full=Replication protein A 34 kDa subunit;
DE            Short=RP-A p34;
GN   Name=RPA2; Synonyms=REPA2, RPA32, RPA34;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0000730; P:DNA recombinase assembly; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFA4_HUMAN              Reviewed;         261 AA.
AC   Q13156; Q3SY03;
DE   RecName: Full=Replication protein A 30 kDa subunit;
DE            Short=RP-A p30;
DE   AltName: Full=Replication factor A protein 4;
DE            Short=RF-A protein 4;
GN   Name=RPA4;
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0000077; P:DNA damage checkpoint; IDA:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.
//
ID   RFA3_HUMAN              Reviewed;         121 AA.
AC   P35244; Q549U6;
DE   RecName: Full=Replication protein A 14 kDa subunit;
DE            Short=RP-A p14;
DE   AltName: Full=Replication factor A protein 3;
DE            Short=RF-A protein 3;
GN   Name=RPA3; Synonyms=REPA3, RPA14;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0000730; P:DNA recombinase assembly; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFAL1_HUMAN             Reviewed;         287 AA.
AC   F8VTS6;
DE   RecName: Full=Ret finger protein-like 4A-like protein 1;
GN   Name=RFPL4AL1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RFC1_HUMAN              Reviewed;        1148 AA.
AC   P35251; A8K6E7; Q5XKF5; Q6PKU0; Q86V41; Q86V46;
DE   RecName: Full=Replication factor C subunit 1;
DE   AltName: Full=Activator 1 140 kDa subunit;
DE            Short=A1 140 kDa subunit;
DE   AltName: Full=Activator 1 large subunit;
DE   AltName: Full=Activator 1 subunit 1;
DE   AltName: Full=DNA-binding protein PO-GA;
DE   AltName: Full=Replication factor C 140 kDa subunit;
DE            Short=RF-C 140 kDa subunit;
DE            Short=RFC140;
DE   AltName: Full=Replication factor C large subunit;
GN   Name=RFC1; Synonyms=RFC140;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFC2_HUMAN              Reviewed;         354 AA.
AC   P35250; B5BU07; D3DXG3; P32846; Q9BU93;
DE   RecName: Full=Replication factor C subunit 2;
DE   AltName: Full=Activator 1 40 kDa subunit;
DE            Short=A1 40 kDa subunit;
DE   AltName: Full=Activator 1 subunit 2;
DE   AltName: Full=Replication factor C 40 kDa subunit;
DE            Short=RF-C 40 kDa subunit;
DE            Short=RFC40;
GN   Name=RFC2;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; TAS:Reactome.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFC3_HUMAN              Reviewed;         356 AA.
AC   P40938; C9JU95; O15252; Q5W0E8;
DE   RecName: Full=Replication factor C subunit 3;
DE   AltName: Full=Activator 1 38 kDa subunit;
DE            Short=A1 38 kDa subunit;
DE   AltName: Full=Activator 1 subunit 3;
DE   AltName: Full=Replication factor C 38 kDa subunit;
DE            Short=RF-C 38 kDa subunit;
DE            Short=RFC38;
GN   Name=RFC3;
DR   GO; GO:0003689; F:DNA clamp loader activity; TAS:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006260; P:DNA replication; IDA:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; TAS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0046683; P:response to organophosphorus; IEP:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFC4_HUMAN              Reviewed;         363 AA.
AC   P35249; D3DNV2; Q6FHX7;
DE   RecName: Full=Replication factor C subunit 4;
DE   AltName: Full=Activator 1 37 kDa subunit;
DE            Short=A1 37 kDa subunit;
DE   AltName: Full=Activator 1 subunit 4;
DE   AltName: Full=Replication factor C 37 kDa subunit;
DE            Short=RF-C 37 kDa subunit;
DE            Short=RFC37;
GN   Name=RFC4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFC5_HUMAN              Reviewed;         340 AA.
AC   P40937; A8MZ62; B3KSX8;
DE   RecName: Full=Replication factor C subunit 5;
DE   AltName: Full=Activator 1 36 kDa subunit;
DE            Short=A1 36 kDa subunit;
DE   AltName: Full=Activator 1 subunit 5;
DE   AltName: Full=Replication factor C 36 kDa subunit;
DE            Short=RF-C 36 kDa subunit;
DE            Short=RFC36;
GN   Name=RFC5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006297; P:nucleotide-excision repair, DNA gap filling; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0000722; P:telomere maintenance via recombination; TAS:Reactome.
DR   GO; GO:0032201; P:telomere maintenance via semi-conservative replication; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
//
ID   RFESD_HUMAN             Reviewed;         157 AA.
AC   Q8TAC1; J3KPH1;
DE   RecName: Full=Rieske domain-containing protein;
GN   Name=RFESD;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
//
ID   RFFL_HUMAN              Reviewed;         363 AA.
AC   Q8WZ73; E1P633; Q8NHW0; Q8TBY7; Q96BE6;
DE   RecName: Full=E3 ubiquitin-protein ligase rififylin;
DE            EC=6.3.2.-;
DE   AltName: Full=Caspase regulator CARP2;
DE   AltName: Full=Caspases-8 and -10-associated RING finger protein 2;
DE            Short=CARP-2;
DE   AltName: Full=FYVE-RING finger protein Sakura;
DE            Short=Fring;
DE   AltName: Full=RING finger and FYVE-like domain-containing protein 1;
DE   AltName: Full=RING finger protein 189;
DE   AltName: Full=RING finger protein 34-like;
GN   Name=RFFL; Synonyms=RNF189, RNF34L;
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:2001271; P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; IMP:UniProtKB.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:1901797; P:negative regulation of signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010762; P:regulation of fibroblast migration; ISS:UniProtKB.
DR   GO; GO:0032006; P:regulation of TOR signaling; IC:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   RFIP1_HUMAN             Reviewed;        1283 AA.
AC   Q6WKZ4; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ6; Q86YV4; Q8TDL1;
AC   Q9H642;
DE   RecName: Full=Rab11 family-interacting protein 1;
DE            Short=Rab11-FIP1;
DE   AltName: Full=Rab-coupling protein;
GN   Name=RAB11FIP1; Synonyms=RCP;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RFIP2_HUMAN             Reviewed;         512 AA.
AC   Q7L804; A6NEI4; Q9Y2F0;
DE   RecName: Full=Rab11 family-interacting protein 2;
DE            Short=Rab11-FIP2;
DE   AltName: Full=NRip11;
GN   Name=RAB11FIP2; Synonyms=KIAA0941;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.
DR   GO; GO:0035773; P:insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0045055; P:regulated secretory pathway; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   RFIP3_HUMAN             Reviewed;         756 AA.
AC   O75154; B0QYI8; B0QYT8; B1AHQ0; B4DEI7; B4DZR6; Q4VXV7; Q7Z5E9;
AC   Q9H155; Q9H1G0; Q9NUI0;
DE   RecName: Full=Rab11 family-interacting protein 3;
DE            Short=FIP3-Rab11;
DE            Short=Rab11-FIP3;
DE   AltName: Full=Arfophilin-1;
DE   AltName: Full=EF hands-containing Rab-interacting protein;
DE            Short=Eferin;
DE   AltName: Full=MU-MB-17.148;
GN   Name=RAB11FIP3; Synonyms=ARFO1, KIAA0665;
DR   GO; GO:0030306; F:ADP-ribosylation factor binding; IPI:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; IDA:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
//
ID   RFIP4_HUMAN             Reviewed;         637 AA.
AC   Q86YS3; Q52LI1; Q8N829; Q8NDT7; Q969D8;
DE   RecName: Full=Rab11 family-interacting protein 4;
DE            Short=FIP4-Rab11;
DE            Short=Rab11-FIP4;
DE   AltName: Full=Arfophilin-2;
GN   Name=RAB11FIP4; Synonyms=ARFO2, KIAA1821;
DR   GO; GO:0030306; F:ADP-ribosylation factor binding; IPI:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RFIP5_HUMAN             Reviewed;         653 AA.
AC   Q9BXF6; O94939; Q9P0M1;
DE   RecName: Full=Rab11 family-interacting protein 5;
DE            Short=Rab11-FIP5;
DE   AltName: Full=Gamma-SNAP-associated factor 1;
DE            Short=Gaf-1;
DE   AltName: Full=Phosphoprotein pp75;
DE   AltName: Full=Rab11-interacting protein Rip11;
GN   Name=RAB11FIP5; Synonyms=GAF1, KIAA0857, RIP11;
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071468; P:cellular response to acidity; IDA:UniProtKB.
DR   GO; GO:0035773; P:insulin secretion involved in cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0045055; P:regulated secretory pathway; ISS:UniProtKB.
DR   GO; GO:2000008; P:regulation of protein localization to cell surface; IMP:UniProtKB.
//
ID   RFL3S_HUMAN             Reviewed;         107 AA.
AC   P0C7P2; Q5TI83; Q5TI84;
DE   RecName: Full=Putative protein RFPL3S;
DE   AltName: Full=RFPL3 antisense RNA 1;
DE   AltName: Full=RFPL3 antisense gene protein 1;
DE   AltName: Full=Ret finger protein-like 3 antisense gene protein;
GN   Name=RFPL3S; Synonyms=RFPL3-AS1;
//
ID   RFNG_HUMAN              Reviewed;         331 AA.
AC   Q9Y644; O00588;
DE   RecName: Full=Beta-1,3-N-acetylglucosaminyltransferase radical fringe;
DE            EC=2.4.1.222;
DE   AltName: Full=O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;
GN   Name=RFNG;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0033829; F:O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IEA:InterPro.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
//
ID   RFOX1_HUMAN             Reviewed;         397 AA.
AC   Q9NWB1; Q7Z7I7; Q8TAE3; Q8TAF2; Q8WYB2; Q9NS20;
DE   RecName: Full=RNA binding protein fox-1 homolog 1;
DE   AltName: Full=Ataxin-2-binding protein 1;
DE   AltName: Full=Fox-1 homolog A;
DE   AltName: Full=Hexaribonucleotide-binding protein 1;
GN   Name=RBFOX1; Synonyms=A2BP, A2BP1, FOX1, HRNBP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0050658; P:RNA transport; NAS:UniProtKB.
//
ID   RFOX2_HUMAN             Reviewed;         390 AA.
AC   O43251; A4F5G8; A8K5Z5; B0QYY8; B0QYY9; Q0PRL5; Q0VH35; Q5TF71;
AC   Q6IC09; Q8TD00; Q8WYB1; Q96DZ6; Q96NL7; Q9UGW4; Q9UH33;
DE   RecName: Full=RNA binding protein fox-1 homolog 2;
DE   AltName: Full=Fox-1 homolog B;
DE   AltName: Full=Hexaribonucleotide-binding protein 2;
DE   AltName: Full=RNA-binding motif protein 9;
DE   AltName: Full=RNA-binding protein 9;
DE   AltName: Full=Repressor of tamoxifen transcriptional activity;
GN   Name=RBFOX2; Synonyms=FOX2, HRNBP2, RBM9, RTA;
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0021942; P:radial glia guided migration of Purkinje cell; IEA:Ensembl.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; ISS:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0010724; P:regulation of definitive erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RFOX3_HUMAN             Reviewed;         312 AA.
AC   A6NFN3; B4DEG6;
DE   RecName: Full=RNA binding protein fox-1 homolog 3;
DE   AltName: Full=Fox-1 homolog C;
GN   Name=RBFOX3;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RFPL2_HUMAN             Reviewed;         378 AA.
AC   O75678;
DE   RecName: Full=Ret finger protein-like 2;
DE   AltName: Full=RING finger protein 79;
GN   Name=RFPL2; Synonyms=RNF79;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RFPL1_HUMAN             Reviewed;         317 AA.
AC   O75677; Q6IC06; Q9UJ97;
DE   RecName: Full=Ret finger protein-like 1;
DE   AltName: Full=RING finger protein 78;
GN   Name=RFPL1; Synonyms=RFPL1L, RNF78;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RFPL3_HUMAN             Reviewed;         317 AA.
AC   O75679; A2A279; Q6IC03; Q6IC04; Q6NSX3; Q8N5R4;
DE   RecName: Full=Ret finger protein-like 3;
GN   Name=RFPL3;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RFPLA_HUMAN             Reviewed;         287 AA.
AC   A6NLU0;
DE   RecName: Full=Ret finger protein-like 4A;
DE   AltName: Full=RING finger protein 210;
GN   Name=RFPL4A; Synonyms=RFPL4, RNF210;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RFPLB_HUMAN             Reviewed;         263 AA.
AC   Q6ZWI9; A2RU91;
DE   RecName: Full=Ret finger protein-like 4B;
DE   AltName: Full=RING finger protein 211;
GN   Name=RFPL4B; Synonyms=RNF211;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RFT1_HUMAN              Reviewed;         541 AA.
AC   Q96AA3; Q96J03;
DE   RecName: Full=Protein RFT1 homolog;
GN   Name=RFT1;
DR   GO; GO:0005319; F:lipid transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   RFTN2_HUMAN             Reviewed;         501 AA.
AC   Q52LD8; Q14DH4; Q2TA69; Q53QE0; Q53SE1; Q96NM3;
DE   RecName: Full=Raftlin-2;
DE   AltName: Full=Raft-linking protein 2;
GN   Name=RFTN2; Synonyms=C2orf11;
//
ID   RFTN1_HUMAN             Reviewed;         578 AA.
AC   Q14699; Q0D2G0; Q496Y2; Q4QQI7; Q5JB48; Q7Z7P2;
DE   RecName: Full=Raftlin;
DE   AltName: Full=Cell migration-inducing gene 2 protein;
DE   AltName: Full=Raft-linking protein;
GN   Name=RFTN1; Synonyms=KIAA0084; ORFNames=MIG2;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0033227; P:dsRNA transport; IMP:MGI.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IMP:MGI.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; IMP:MGI.
//
ID   RFWD3_HUMAN             Reviewed;         774 AA.
AC   Q6PCD5; A8K585; B2RE35; D3DUJ8; Q5XKR3; Q9H9Q3; Q9NVT4;
DE   RecName: Full=E3 ubiquitin-protein ligase RFWD3;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger and WD repeat domain-containing protein 3;
DE   AltName: Full=RING finger protein 201;
GN   Name=RFWD3; Synonyms=RNF201;
DR   GO; GO:0097371; F:MDM2/MDM4 family protein binding; IPI:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
//
ID   RFX1_HUMAN              Reviewed;         979 AA.
AC   P22670;
DE   RecName: Full=MHC class II regulatory factor RFX1;
DE   AltName: Full=Enhancer factor C;
DE            Short=EF-C;
DE   AltName: Full=Regulatory factor X 1;
DE            Short=RFX;
DE   AltName: Full=Transcription factor RFX1;
GN   Name=RFX1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
//
ID   RFWD2_HUMAN             Reviewed;         731 AA.
AC   Q8NHY2; Q504W6; Q6H103; Q9H6L7;
DE   RecName: Full=E3 ubiquitin-protein ligase RFWD2;
DE            EC=6.3.2.-;
DE   AltName: Full=Constitutive photomorphogenesis protein 1 homolog;
DE            Short=hCOP1;
DE   AltName: Full=RING finger and WD repeat domain protein 2;
DE   AltName: Full=RING finger protein 200;
GN   Name=RFWD2; Synonyms=COP1, RNF200;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RFX2_HUMAN              Reviewed;         723 AA.
AC   P48378; A8K581; B3KNC4; Q6IQ44; Q8SNA2;
DE   RecName: Full=DNA-binding protein RFX2;
DE   AltName: Full=Regulatory factor X 2;
GN   Name=RFX2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RFX3_HUMAN              Reviewed;         749 AA.
AC   P48380; A8K0H5; D3DRH8; D3DRH9; Q5JTL7; Q5JTL8; Q6NW13; Q8WTU4;
AC   Q95HL5; Q95HL6;
DE   RecName: Full=Transcription factor RFX3;
DE   AltName: Full=Regulatory factor X 3;
GN   Name=RFX3;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0048469; P:cell maturation; ISS:BHF-UCL.
DR   GO; GO:0042384; P:cilium assembly; ISS:BHF-UCL.
DR   GO; GO:0060285; P:cilium-dependent cell motility; ISS:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; ISS:UniProtKB.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:2000078; P:positive regulation of type B pancreatic cell development; ISS:BHF-UCL.
DR   GO; GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:GOC.
DR   GO; GO:0072560; P:type B pancreatic cell maturation; IEA:Ensembl.
//
ID   RFX4_HUMAN              Reviewed;         735 AA.
AC   Q33E94; A8K5Y0; B2RDW4; Q33DW6; Q33DW7; Q33E95; Q6YM53; Q8MHQ1;
AC   Q8NC78; Q8NDF9; Q8SNA1; Q96S80; Q9BXI0;
DE   RecName: Full=Transcription factor RFX4;
DE   AltName: Full=Regulatory factor X 4;
DE   AltName: Full=Testis development protein NYD-SP10;
GN   Name=RFX4;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0021696; P:cerebellar cortex morphogenesis; IEA:Ensembl.
DR   GO; GO:0021516; P:dorsal spinal cord development; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RFX5_HUMAN              Reviewed;         616 AA.
AC   P48382; D3DV19; Q5VWC3;
DE   RecName: Full=DNA-binding protein RFX5;
DE   AltName: Full=Regulatory factor X 5;
GN   Name=RFX5;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RFX6_HUMAN              Reviewed;         928 AA.
AC   Q8HWS3; Q5T6B3;
DE   RecName: Full=DNA-binding protein RFX6;
DE   AltName: Full=Regulatory factor X 6;
DE   AltName: Full=Regulatory factor X domain-containing protein 1;
GN   Name=RFX6; Synonyms=RFXDC1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; IMP:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:UniProtKB.
DR   GO; GO:0003310; P:pancreatic A cell differentiation; ISS:UniProtKB.
DR   GO; GO:0003311; P:pancreatic D cell differentiation; ISS:UniProtKB.
DR   GO; GO:0090104; P:pancreatic epsilon cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0003309; P:type B pancreatic cell differentiation; ISS:UniProtKB.
//
ID   RFX7_HUMAN              Reviewed;        1363 AA.
AC   Q2KHR2; Q6ZRR1; Q6ZTY6; Q8N3J0; Q9H7A9; Q9H956;
DE   RecName: Full=DNA-binding protein RFX7;
DE   AltName: Full=Regulatory factor X 7;
DE   AltName: Full=Regulatory factor X domain-containing protein 2;
GN   Name=RFX7; Synonyms=RFXDC2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   RFX8_HUMAN              Reviewed;         586 AA.
AC   Q6ZV50; B4DQ32;
DE   RecName: Full=DNA-binding protein RFX8;
DE   AltName: Full=Regulatory factor X 8;
GN   Name=RFX8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RFXAP_HUMAN             Reviewed;         272 AA.
AC   O00287; B2R9T8; Q5VZM6; Q8TC40;
DE   RecName: Full=Regulatory factor X-associated protein;
DE            Short=RFX-associated protein;
DE   AltName: Full=RFX DNA-binding complex 36 kDa subunit;
GN   Name=RFXAP;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   RFXK_HUMAN              Reviewed;         260 AA.
AC   O14593; O95839; Q24JQ1; Q6FGA8;
DE   RecName: Full=DNA-binding protein RFXANK;
DE   AltName: Full=Ankyrin repeat family A protein 1;
DE   AltName: Full=Regulatory factor X subunit B;
DE            Short=RFX-B;
DE   AltName: Full=Regulatory factor X-associated ankyrin-containing protein;
GN   Name=RFXANK; Synonyms=ANKRA1, RFXB;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RGAG4_HUMAN             Reviewed;         569 AA.
AC   Q5HYW3; A7E2W7; Q8NCM4; Q9NPX1;
DE   RecName: Full=Retrotransposon gag domain-containing protein 4;
GN   Name=RGAG4; Synonyms=KIAA2001;
//
ID   RGAG1_HUMAN             Reviewed;        1388 AA.
AC   Q8NET4; Q9P2M8;
DE   RecName: Full=Retrotransposon gag domain-containing protein 1;
DE   AltName: Full=Tumor antigen BJ-HCC-23;
GN   Name=RGAG1; Synonyms=KIAA1318;
//
ID   RGAP1_HUMAN             Reviewed;         632 AA.
AC   Q9H0H5; Q6PJ26; Q9NWN2; Q9P250; Q9P2W2;
DE   RecName: Full=Rac GTPase-activating protein 1;
DE   AltName: Full=Male germ cell RacGap;
DE            Short=MgcRacGAP;
DE   AltName: Full=Protein CYK4 homolog;
DE            Short=CYK4;
DE            Short=HsCYK-4;
GN   Name=RACGAP1; Synonyms=KIAA1478, MGCRACGAP;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000915; P:actomyosin contractile ring assembly; IMP:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007108; P:cytokinesis, initiation of separation; IMP:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; TAS:Reactome.
DR   GO; GO:0000281; P:mitotic cytokinesis; IDA:UniProtKB.
DR   GO; GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IDA:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0051256; P:spindle midzone assembly involved in mitosis; IDA:UniProtKB.
DR   GO; GO:0008272; P:sulfate transport; IDA:UniProtKB.
//
ID   RGCC_HUMAN              Reviewed;         137 AA.
AC   Q9H4X1; Q6NZ48; Q9UL69;
DE   RecName: Full=Regulator of cell cycle RGCC;
DE   AltName: Full=Response gene to complement 32 protein;
DE            Short=RGC-32;
GN   Name=RGCC; Synonyms=C13orf15, RGC32;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0006956; P:complement activation; IMP:BHF-UCL.
DR   GO; GO:0072537; P:fibroblast activation; ISS:UniProtKB.
DR   GO; GO:0071850; P:mitotic cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:2000048; P:negative regulation of cell-cell adhesion mediated by cadherin; IDA:BHF-UCL.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IMP:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0001100; P:negative regulation of exit from mitosis; IDA:BHF-UCL.
DR   GO; GO:0090272; P:negative regulation of fibroblast growth factor production; IDA:BHF-UCL.
DR   GO; GO:1901991; P:negative regulation of mitotic cell cycle phase transition; IDA:BHF-UCL.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0031659; P:positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IMP:BHF-UCL.
DR   GO; GO:2000573; P:positive regulation of DNA biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0003331; P:positive regulation of extracellular matrix constituent secretion; IDA:BHF-UCL.
DR   GO; GO:1901313; P:positive regulation of gene expression involved in extracellular matrix organization; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IMP:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:BHF-UCL.
//
ID   RGF1A_HUMAN             Reviewed;         481 AA.
AC   Q8N9B8; Q8TBF1;
DE   RecName: Full=Ras-GEF domain-containing family member 1A;
GN   Name=RASGEF1A;
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:FlyBase.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; IDA:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGF1B_HUMAN             Reviewed;         473 AA.
AC   Q0VAM2; Q0VAM1; Q4W5L7; Q4W5M3; Q96MY8;
DE   RecName: Full=Ras-GEF domain-containing family member 1B;
DE   AltName: Full=GPI gamma-4;
GN   Name=RASGEF1B; Synonyms=GPIG4;
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; IDA:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGF1C_HUMAN             Reviewed;         466 AA.
AC   Q8N431; D3DWQ7; Q7Z4T0; Q8NA49;
DE   RecName: Full=Ras-GEF domain-containing family member 1C;
GN   Name=RASGEF1C;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGDSR_HUMAN             Reviewed;         473 AA.
AC   Q8IZJ4;
DE   RecName: Full=Ral-GDS-related protein;
DE            Short=hRGR;
DE   AltName: Full=Ral guanine nucleotide dissociation stimulator-like 4;
DE            Short=RalGDS-like 4;
GN   Name=RGL4; Synonyms=RGR;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGL1_HUMAN              Reviewed;         768 AA.
AC   Q9NZL6; Q5SXQ2; Q5SXQ6; Q9HBY3; Q9HBY4; Q9NZL5; Q9UG43; Q9Y2G6;
DE   RecName: Full=Ral guanine nucleotide dissociation stimulator-like 1;
DE            Short=RalGDS-like 1;
GN   Name=RGL1; Synonyms=KIAA0959, RGL;
DR   GO; GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0032315; P:regulation of Ral GTPase activity; NAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RGL2_HUMAN              Reviewed;         777 AA.
AC   O15211; Q5STK0; Q9Y3F3;
DE   RecName: Full=Ral guanine nucleotide dissociation stimulator-like 2;
DE            Short=RalGDS-like 2;
DE   AltName: Full=RalGDS-like factor;
DE   AltName: Full=Ras-associated protein RAB2L;
GN   Name=RGL2; Synonyms=RAB2L;
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; NAS:GOC.
//
ID   RGL3_HUMAN              Reviewed;         710 AA.
AC   Q3MIN7; B5ME84; B7ZL22; Q0P6G0;
DE   RecName: Full=Ral guanine nucleotide dissociation stimulator-like 3;
DE            Short=RalGDS-like 3;
GN   Name=RGL3;
DR   GO; GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGMA_HUMAN              Reviewed;         450 AA.
AC   Q96B86; B2RTW1; B7Z5S8; F5GXQ7; F5GZU6; G3V518; Q0JV97; Q8NC80;
AC   Q9H0E6; Q9NPM3;
DE   RecName: Full=Repulsive guidance molecule A;
DE   AltName: Full=RGM domain family member A;
DE   Flags: Precursor;
GN   Name=RGMA; Synonyms=RGM;
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
//
ID   RGMC_HUMAN              Reviewed;         426 AA.
AC   Q6ZVN8; B1ALI7; Q2PQ63; Q6IMF6; Q8NAH2; Q8WVJ5;
DE   RecName: Full=Hemojuvelin;
DE   AltName: Full=Hemochromatosis type 2 protein;
DE   AltName: Full=RGM domain family member C;
DE   Flags: Precursor;
GN   Name=HFE2; Synonyms=HJV, RGMC;
DR   GO; GO:0015026; F:coreceptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IDA:MGI.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   RGMB_HUMAN              Reviewed;         437 AA.
AC   Q6NW40; D6R9A0; Q8NC92;
DE   RecName: Full=RGM domain family member B;
DE   AltName: Full=DRG11-responsive axonal guidance and outgrowth of neurite;
DE            Short=DRAGON;
DE   Flags: Precursor;
GN   Name=RGMB;
DR   GO; GO:0042802; F:identical protein binding; ISS:HGNC.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:HGNC.
DR   GO; GO:0007155; P:cell adhesion; ISS:HGNC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:HGNC.
DR   GO; GO:0007165; P:signal transduction; ISS:HGNC.
//
ID   RGN_HUMAN               Reviewed;         299 AA.
AC   Q15493; A4FTW1; A8K271; Q53FC9; Q5JRR5;
DE   RecName: Full=Regucalcin;
DE            Short=RC;
DE   AltName: Full=Gluconolactonase;
DE            Short=GNL;
DE            EC=3.1.1.17;
DE   AltName: Full=Senescence marker protein 30;
DE            Short=SMP-30;
GN   Name=RGN; Synonyms=SMP30;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:InterPro.
DR   GO; GO:0004341; F:gluconolactonase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0019853; P:L-ascorbic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; ISS:UniProtKB.
DR   GO; GO:0050848; P:regulation of calcium-mediated signaling; ISS:UniProtKB.
//
ID   RGP1_HUMAN              Reviewed;         391 AA.
AC   Q92546; Q5TCV5;
DE   RecName: Full=Retrograde Golgi transport protein RGP1 homolog;
GN   Name=RGP1; Synonyms=KIAA0258;
//
ID   RGPA1_HUMAN             Reviewed;        2036 AA.
AC   Q6GYQ0; A6NMA4; B9EK38; C5NU19; O94960; Q6GYP9; Q6ZT23; Q86YF3;
AC   Q86YF5; Q8ND69;
DE   RecName: Full=Ral GTPase-activating protein subunit alpha-1;
DE   AltName: Full=GAP-related-interacting partner to E12;
DE            Short=GRIPE;
DE   AltName: Full=GTPase-activating Rap/Ran-GAP domain-like 1;
DE   AltName: Full=Tuberin-like protein 1;
DE   AltName: Full=p240;
GN   Name=RALGAPA1; Synonyms=GARNL1, KIAA0884, TULIP1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0017123; F:Ral GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0032859; P:activation of Ral GTPase activity; ISS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:RefGenome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   RGPA2_HUMAN             Reviewed;        1873 AA.
AC   Q2PPJ7; Q4VXU6; Q5JUA3; Q5JUA4; Q5T9K3; Q96CX9; Q9BQT7; Q9H9D9;
AC   Q9ULE8;
DE   RecName: Full=Ral GTPase-activating protein subunit alpha-2;
DE   AltName: Full=250 kDa substrate of Akt;
DE            Short=AS250;
DE   AltName: Full=p220;
GN   Name=RALGAPA2; Synonyms=C20orf74, KIAA1272;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0017123; F:Ral GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0032859; P:activation of Ral GTPase activity; ISS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
//
ID   RGPD1_HUMAN             Reviewed;        1748 AA.
AC   P0DJD0; P0C839; Q68DN6; Q6V1X0;
DE   RecName: Full=RANBP2-like and GRIP domain-containing protein 1;
DE   AltName: Full=Ran-binding protein 2-like 6;
DE            Short=RanBP2-like 6;
DE            Short=RanBP2L6;
GN   Name=RGPD1; Synonyms=RANBP2L6, RGP1;
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   RGPD5_HUMAN             Reviewed;        1765 AA.
AC   Q99666; Q53QN2; Q53T03; Q59GM7; Q9H0B2;
DE   RecName: Full=RANBP2-like and GRIP domain-containing protein 5/6;
DE   AltName: Full=Ran-binding protein 2-like 1/2;
DE            Short=RanBP2-like 1/2;
DE            Short=RanBP2L1;
DE            Short=RanBP2L2;
DE   AltName: Full=Sperm membrane protein BS-63;
GN   Name=RGPD5; Synonyms=RANBP2L1, RGP5, RGP7, RGPD7;
GN   and
GN   Name=RGPD6; Synonyms=RANBP2L2, RGP6;
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   RGPD2_HUMAN             Reviewed;        1756 AA.
AC   P0DJD1; P0C839; Q68DN6; Q6V1X0;
DE   RecName: Full=RANBP2-like and GRIP domain-containing protein 2;
DE   AltName: Full=Ran-binding protein 2-like 2;
DE            Short=RanBP2-like 2;
DE            Short=RanBP2L2;
GN   Name=RGPD2; Synonyms=RANBP2L2, RGP2;
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   RGPD4_HUMAN             Reviewed;        1758 AA.
AC   Q7Z3J3; B9A029;
DE   RecName: Full=RanBP2-like and GRIP domain-containing protein 4;
GN   Name=RGPD4; Synonyms=RGP4;
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   RGPD8_HUMAN             Reviewed;        1765 AA.
AC   O14715; Q5CZA8;
DE   RecName: Full=RANBP2-like and GRIP domain-containing protein 8;
DE   AltName: Full=Ran-binding protein 2-like 3;
DE            Short=RanBP2-like 3;
DE            Short=RanBP2L3;
GN   Name=RGPD8; Synonyms=RANBP2ALPHA, RANBP2L1, RANBP2L3;
DR   GO; GO:0008536; F:Ran GTPase binding; NAS:UniProtKB.
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   RGPS1_HUMAN             Reviewed;         557 AA.
AC   Q5JS13; B4DR86; E9PBQ5; O15059; Q5JT60; Q5JT65; Q5JUG5; Q8N4S6;
AC   Q8N5H4; Q8WUV7; Q9NZ16;
DE   RecName: Full=Ras-specific guanine nucleotide-releasing factor RalGPS1;
DE   AltName: Full=Ral GEF with PH domain and SH3-binding motif 1;
DE   AltName: Full=Ral guanine nucleotide exchange factor 2;
DE            Short=RalGEF 2;
DE   AltName: Full=RalA exchange factor RalGPS1;
GN   Name=RALGPS1; Synonyms=KIAA0351, RALGEF2;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0008321; F:Ral guanyl-nucleotide exchange factor activity; IDA:FlyBase.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; NAS:GOC.
DR   GO; GO:0032315; P:regulation of Ral GTPase activity; IDA:GOC.
DR   GO; GO:0032485; P:regulation of Ral protein signal transduction; IDA:FlyBase.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGPD3_HUMAN             Reviewed;        1758 AA.
AC   A6NKT7; B8ZZM4;
DE   RecName: Full=RanBP2-like and GRIP domain-containing protein 3;
GN   Name=RGPD3; Synonyms=RGP3;
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
//
ID   RGPS2_HUMAN             Reviewed;         583 AA.
AC   Q86X27; B7Z7B1; Q5T5Z1; Q5VZ67; Q9NW78;
DE   RecName: Full=Ras-specific guanine nucleotide-releasing factor RalGPS2;
DE   AltName: Full=Ral GEF with PH domain and SH3-binding motif 2;
DE   AltName: Full=RalA exchange factor RalGPS2;
GN   Name=RALGPS2;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RGRF1_HUMAN             Reviewed;        1273 AA.
AC   Q13972; F8VPA5; H0YKF2; J3KQP9; Q16027;
DE   RecName: Full=Ras-specific guanine nucleotide-releasing factor 1;
DE            Short=Ras-GRF1;
DE   AltName: Full=Guanine nucleotide-releasing protein;
DE            Short=GNRP;
DE   AltName: Full=Ras-specific nucleotide exchange factor CDC25;
GN   Name=RASGRF1; Synonyms=CDC25, GNRP, GRF1;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; ISS:HGNC.
DR   GO; GO:0007616; P:long-term memory; NAS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:HGNC.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; ISS:HGNC.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0035020; P:regulation of Rac protein signal transduction; ISS:HGNC.
DR   GO; GO:0046578; P:regulation of Ras protein signal transduction; ISS:HGNC.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   RGRF2_HUMAN             Reviewed;        1237 AA.
AC   O14827; B9EG89; Q9UK56;
DE   RecName: Full=Ras-specific guanine nucleotide-releasing factor 2;
DE            Short=Ras-GRF2;
DE   AltName: Full=Ras guanine nucleotide exchange factor 2;
GN   Name=RASGRF2; Synonyms=GRF2;
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   RGR_HUMAN               Reviewed;         291 AA.
AC   P47804; A6NKK7; Q96FC5;
DE   RecName: Full=RPE-retinal G protein-coupled receptor;
GN   Name=RGR;
DR   GO; GO:0004950; F:chemokine receptor activity; IEA:InterPro.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR   GO; GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RGS10_HUMAN             Reviewed;         173 AA.
AC   O43665; A8K408; B1AMR8; Q6IAZ6; Q96GN0;
DE   RecName: Full=Regulator of G-protein signaling 10;
DE            Short=RGS10;
GN   Name=RGS10;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS12_HUMAN             Reviewed;        1447 AA.
AC   O14924; B1AQ30; B1AQ31; B1AQ32; B7Z764; E7EMN9; O14922; O14923;
AC   O43510; O75338; Q147X0; Q8WX95;
DE   RecName: Full=Regulator of G-protein signaling 12;
DE            Short=RGS12;
GN   Name=RGS12;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0030695; F:GTPase regulator activity; IDA:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0050790; P:regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RGS11_HUMAN             Reviewed;         467 AA.
AC   O94810; O75883; Q4TT71; Q4TT72;
DE   RecName: Full=Regulator of G-protein signaling 11;
DE            Short=RGS11;
GN   Name=RGS11;
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IPI:UniProt.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS13_HUMAN             Reviewed;         159 AA.
AC   O14921; Q6PGR2; Q8TD63; Q9BX45;
DE   RecName: Full=Regulator of G-protein signaling 13;
DE            Short=RGS13;
GN   Name=RGS13;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS14_HUMAN             Reviewed;         566 AA.
AC   O43566; O43565; Q506M1; Q6ZWA4; Q8TD62;
DE   RecName: Full=Regulator of G-protein signaling 14;
DE            Short=RGS14;
GN   Name=RGS14;
DR   GO; GO:0005092; F:GDP-dissociation inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; ISS:UniProtKB.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:GOC.
DR   GO; GO:0007612; P:learning; ISS:UniProtKB.
DR   GO; GO:0007616; P:long-term memory; ISS:UniProtKB.
DR   GO; GO:0060291; P:long-term synaptic potentiation; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0031914; P:negative regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0043620; P:regulation of DNA-templated transcription in response to stress; ISS:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0008542; P:visual learning; ISS:UniProtKB.
DR   GO; GO:0010070; P:zygote asymmetric cell division; ISS:UniProtKB.
//
ID   RGS16_HUMAN             Reviewed;         202 AA.
AC   O15492; B2R4M4; Q5VYN9; Q99701;
DE   RecName: Full=Regulator of G-protein signaling 16;
DE            Short=RGS16;
DE   AltName: Full=A28-RGS14P;
DE   AltName: Full=Retinal-specific RGS;
DE            Short=RGS-r;
DE            Short=hRGS-r;
DE   AltName: Full=Retinally abundant regulator of G-protein signaling;
GN   Name=RGS16; Synonyms=RGSR;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RGS18_HUMAN             Reviewed;         235 AA.
AC   Q9NS28; B2RD23;
DE   RecName: Full=Regulator of G-protein signaling 18;
DE            Short=RGS18;
GN   Name=RGS18; Synonyms=RGS13;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS19_HUMAN             Reviewed;         217 AA.
AC   P49795; A8K216; E1P5G9; Q53XN0; Q8TD60;
DE   RecName: Full=Regulator of G-protein signaling 19;
DE            Short=RGS19;
DE   AltName: Full=G-alpha-interacting protein;
DE            Short=GAIP;
GN   Name=RGS19; Synonyms=GAIP, GNAI3IP;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS17_HUMAN             Reviewed;         210 AA.
AC   Q9UGC6; Q5TF49; Q8TD61; Q9UJS8;
DE   RecName: Full=Regulator of G-protein signaling 17;
DE            Short=RGS17;
GN   Name=RGS17;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS1_HUMAN              Reviewed;         209 AA.
AC   Q08116; B2RDM9; B4DZY0; Q07918; Q9H1W2;
DE   RecName: Full=Regulator of G-protein signaling 1;
DE            Short=RGS1;
DE   AltName: Full=B-cell activation protein BL34;
DE   AltName: Full=Early response protein 1R20;
GN   Name=RGS1; Synonyms=1R20, BL34, IER1;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS20_HUMAN             Reviewed;         388 AA.
AC   O76081; Q96BG9;
DE   RecName: Full=Regulator of G-protein signaling 20;
DE            Short=RGS20;
DE   AltName: Full=Gz-selective GTPase-activating protein;
DE            Short=G(z)GAP;
DE            Short=Gz-GAP;
DE   AltName: Full=Regulator of G-protein signaling Z1;
DE   AltName: Full=Regulator of Gz-selective protein signaling 1;
GN   Name=RGS20; Synonyms=RGSZ1, ZGAP1;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS21_HUMAN             Reviewed;         152 AA.
AC   Q2M5E4;
DE   RecName: Full=Regulator of G-protein signaling 21;
DE            Short=RGS21;
GN   Name=RGS21;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS22_HUMAN             Reviewed;        1264 AA.
AC   Q8NE09; A8K944; Q569L2; Q86Y71; Q9BYZ4; Q9UFN6;
DE   RecName: Full=Regulator of G-protein signaling 22;
DE            Short=RGS22;
GN   Name=RGS22;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS2_HUMAN              Reviewed;         211 AA.
AC   P41220; Q6I9U5;
DE   RecName: Full=Regulator of G-protein signaling 2;
DE            Short=RGS2;
DE   AltName: Full=Cell growth-inhibiting gene 31 protein;
DE   AltName: Full=G0/G1 switch regulatory protein 8;
GN   Name=RGS2; Synonyms=G0S8; ORFNames=GIG31;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:BHF-UCL.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; ISS:BHF-UCL.
DR   GO; GO:0010519; P:negative regulation of phospholipase activity; ISS:BHF-UCL.
DR   GO; GO:0060452; P:positive regulation of cardiac muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0071877; P:regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0055119; P:relaxation of cardiac muscle; ISS:BHF-UCL.
DR   GO; GO:0060087; P:relaxation of vascular smooth muscle; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS3_HUMAN              Reviewed;        1198 AA.
AC   P49796; A6NHA0; A8K0V1; B3KUB2; Q5VXB8; Q5VXC1; Q5VZ05; Q5VZ06;
AC   Q6ZRM5; Q8IUQ1; Q8NC47; Q8NFN4; Q8NFN5; Q8NFN6; Q8TD59; Q8TD68;
AC   Q8WV02; Q8WXA0;
DE   RecName: Full=Regulator of G-protein signaling 3;
DE            Short=RGP3;
DE            Short=RGS3;
GN   Name=RGS3;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS4_HUMAN              Reviewed;         205 AA.
AC   P49798; A7XA56; A7XA58; A7XA59; A7YVV7; B1APZ3;
DE   RecName: Full=Regulator of G-protein signaling 4;
DE            Short=RGP4;
DE            Short=RGS4;
GN   Name=RGS4;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS5_HUMAN              Reviewed;         181 AA.
AC   O15539; E9PMP5; Q53XA9; Q599J0;
DE   RecName: Full=Regulator of G-protein signaling 5;
DE            Short=RGS5;
GN   Name=RGS5;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS6_HUMAN              Reviewed;         472 AA.
AC   P49758; C9JE95; F8W7W5; O75576; O75577; Q7Z4K3; Q7Z4K4; Q7Z4K5;
AC   Q7Z4K6; Q8TE13; Q8TE14; Q8TE15; Q8TE16; Q8TE17; Q8TE18; Q8TE19;
AC   Q8TE20; Q8TE21; Q8TE22; Q9UDS8; Q9UDT0; Q9Y245; Q9Y647;
DE   RecName: Full=Regulator of G-protein signaling 6;
DE            Short=RGS6;
DE   AltName: Full=S914;
GN   Name=RGS6;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS7_HUMAN              Reviewed;         495 AA.
AC   P49802; Q5T3H4; Q8TD66; Q8TD67; Q8WW09; Q9UNU7; Q9Y6B9;
DE   RecName: Full=Regulator of G-protein signaling 7;
DE            Short=RGS7;
GN   Name=RGS7;
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IPI:UniProt.
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS8_HUMAN              Reviewed;         180 AA.
AC   P57771; B4DGL9; Q3SYD2;
DE   RecName: Full=Regulator of G-protein signaling 8;
DE            Short=RGS8;
GN   Name=RGS8;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GOC.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RGS9_HUMAN              Reviewed;         674 AA.
AC   O75916; A8K3C0; O75573; Q696R2; Q8TD64; Q8TD65; Q9HC32; Q9HC33;
DE   RecName: Full=Regulator of G-protein signaling 9;
DE            Short=RGS9;
GN   Name=RGS9;
DR   GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007212; P:dopamine receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RGSL_HUMAN              Reviewed;        1076 AA.
AC   A5PLK6; A2A2Z0; A6PVM2; A6PVM3; Q0VAJ4; Q0VAJ5; Q6ZRL0; Q86UV0;
AC   Q9H084;
DE   RecName: Full=Regulator of G-protein signaling protein-like;
GN   Name=RGSL1; Synonyms=RGSL, RGSL2;
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   RHAG_HUMAN              Reviewed;         409 AA.
AC   Q02094; B2R8T8; O43514; O43515; Q7L8L3; Q9H454;
DE   RecName: Full=Ammonium transporter Rh type A;
DE   AltName: Full=Erythrocyte membrane glycoprotein Rh50;
DE   AltName: Full=Erythrocyte plasma membrane 50 kDa glycoprotein;
DE            Short=Rh50A;
DE   AltName: Full=Rhesus blood group family type A glycoprotein;
DE            Short=Rh family type A glycoprotein;
DE            Short=Rh type A glycoprotein;
DE   AltName: Full=Rhesus blood group-associated ammonia channel;
DE   AltName: Full=Rhesus blood group-associated glycoprotein;
DE   AltName: CD_antigen=CD241;
GN   Name=RHAG; Synonyms=RH50;
DR   GuidetoPHARMACOLOGY; 1198; -.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0030506; F:ankyrin binding; IPI:UniProtKB.
DR   GO; GO:0072488; P:ammonium transmembrane transport; IDA:GOC.
DR   GO; GO:0015696; P:ammonium transport; IDA:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0015670; P:carbon dioxide transport; IDA:UniProtKB.
DR   GO; GO:0006873; P:cellular ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   RHAS1_HUMAN             Reviewed;          59 AA.
AC   Q9BWJ2;
DE   RecName: Full=Putative uncharacterized protein encoded by RHPN1-AS1;
DE   AltName: Full=RHPN1 antisense RNA 1;
DE   AltName: Full=RHPN1 antisense gene protein 1;
GN   Name=RHPN1-AS1; Synonyms=C8orf51;
//
ID   RHBD2_HUMAN             Reviewed;         364 AA.
AC   Q6NTF9; Q7L534; Q9H5W6; Q9UDT2;
DE   RecName: Full=Rhomboid domain-containing protein 2;
GN   Name=RHBDD2; Synonyms=RHBDL7;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   RHBD3_HUMAN             Reviewed;         386 AA.
AC   Q9Y3P4; Q6I9X3; Q9UGQ7;
DE   RecName: Full=Rhomboid domain-containing protein 3;
GN   Name=RHBDD3; Synonyms=C22orf3;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   RHBG_HUMAN              Reviewed;         441 AA.
AC   Q9H310; A8K475; Q5SZW4; Q5SZW6; Q5SZW7; Q6P193; Q6YJI2; Q6YJI3;
DE   RecName: Full=Ammonium transporter Rh type B;
DE   AltName: Full=Rhesus blood group family type B glycoprotein;
DE            Short=Rh family type B glycoprotein;
DE            Short=Rh type B glycoprotein;
GN   Name=RHBG;
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0030506; F:ankyrin binding; IPI:UniProtKB.
DR   GO; GO:0072488; P:ammonium transmembrane transport; IDA:GOC.
DR   GO; GO:0015696; P:ammonium transport; IDA:UniProtKB.
DR   GO; GO:0070634; P:transepithelial ammonium transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   RHBL2_HUMAN             Reviewed;         303 AA.
AC   Q9NX52; B2RNT3; B9EH75; Q6P175; Q8NER8; Q96E02;
DE   RecName: Full=Rhomboid-related protein 2;
DE            Short=RRP2;
DE            EC=3.4.21.105;
DE   AltName: Full=Rhomboid-like protein 2;
DE   Contains:
DE     RecName: Full=Rhomboid-related protein 2, N-terminal fragment;
DE              Short=NTF;
DE   Contains:
DE     RecName: Full=Rhomboid-related protein 2, C-terminal fragment;
DE              Short=CTF;
GN   Name=RHBDL2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
//
ID   RHBL1_HUMAN             Reviewed;         438 AA.
AC   O75783; A2IDC0; A2IDC1; Q0VAX4; Q9NQ85;
DE   RecName: Full=Rhomboid-related protein 1;
DE            Short=RRP;
DE            EC=3.4.21.105;
DE   AltName: Full=Rhomboid-like protein 1;
GN   Name=RHBDL1; Synonyms=RHBDL;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RHBL3_HUMAN             Reviewed;         404 AA.
AC   P58872; A6NMH1; Q495Y6;
DE   RecName: Full=Rhomboid-related protein 3;
DE            EC=3.4.21.105;
DE   AltName: Full=Ventrhoid transmembrane protein;
GN   Name=RHBDL3; Synonyms=RHBDL4, VRHO;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   RHBL4_HUMAN             Reviewed;         315 AA.
AC   Q8TEB9; Q495B9; Q53S43; Q5EBM8; Q6P5V8; Q8IV60; Q9H057;
DE   RecName: Full=Rhomboid-related protein 4;
DE            Short=RRP4;
DE            EC=3.4.21.105;
DE   AltName: Full=Rhomboid domain-containing protein 1;
DE   AltName: Full=Rhomboid-like protein 4;
GN   Name=RHBDD1; Synonyms=RHBDL4; ORFNames=HSD-50, HSD50;
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0034620; P:cellular response to unfolded protein; ISS:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; ISS:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.
DR   GO; GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0010954; P:positive regulation of protein processing; ISS:UniProtKB.
DR   GO; GO:0051047; P:positive regulation of secretion; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; ISS:UniProtKB.
DR   GO; GO:0048515; P:spermatid differentiation; ISS:UniProtKB.
//
ID   RHBT2_HUMAN             Reviewed;         727 AA.
AC   Q9BYZ6; A8K9Z8; D3DSR8; E9PBU2; E9PEI7; O94825; Q8N4A8; Q9BZK6;
DE   RecName: Full=Rho-related BTB domain-containing protein 2;
DE   AltName: Full=Deleted in breast cancer 2 gene protein;
DE   AltName: Full=p83;
GN   Name=RHOBTB2; Synonyms=DBC2, KIAA0717;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHBT1_HUMAN             Reviewed;         696 AA.
AC   O94844;
DE   RecName: Full=Rho-related BTB domain-containing protein 1;
GN   Name=RHOBTB1; Synonyms=KIAA0740;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHCE_HUMAN              Reviewed;         417 AA.
AC   P18577; A7DW68; B7UDF3; B7UDF4; B7UDF5; B7UDF6; B7UDF7; B7UDF8;
AC   B7UDF9; B7UDG0; B7UDG1; B7UDG2; B7UDG3; Q02163; Q02164; Q02165;
AC   Q16160; Q2MJW0; Q2VC86; Q3LTM6; Q6AZX5; Q6J2U3; Q7RU06; Q8IZT2;
AC   Q8IZT3; Q8IZT4; Q8IZT5; Q9UD13; Q9UD14; Q9UD15; Q9UD16; Q9UD73;
AC   Q9UD74; Q9UEC2; Q9UEC3; Q9UPN0;
DE   RecName: Full=Blood group Rh(CE) polypeptide;
DE   AltName: Full=Rh polypeptide 1;
DE            Short=RhPI;
DE   AltName: Full=Rh30A;
DE   AltName: Full=RhIXB;
DE   AltName: Full=Rhesus C/E antigens;
DE   AltName: CD_antigen=CD240CE;
GN   Name=RHCE; Synonyms=RHC, RHE;
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
//
ID   RHBT3_HUMAN             Reviewed;         611 AA.
AC   O94955; A0PJA4; A8K1W9; Q8IW06;
DE   RecName: Full=Rho-related BTB domain-containing protein 3;
DE            EC=3.6.1.-;
GN   Name=RHOBTB3; Synonyms=KIAA0878;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RHCG_HUMAN              Reviewed;         479 AA.
AC   Q9UBD6; A8K4D4; Q6X3Y4;
DE   RecName: Full=Ammonium transporter Rh type C;
DE   AltName: Full=Rh glycoprotein kidney;
DE   AltName: Full=Rhesus blood group family type C glycoprotein;
DE            Short=Rh family type C glycoprotein;
DE            Short=Rh type C glycoprotein;
DE   AltName: Full=Tumor-related protein DRC2;
GN   Name=RHCG; Synonyms=C15orf6, CDRC2, PDRC2, RHGK;
DR   GuidetoPHARMACOLOGY; 1200; -.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0030506; F:ankyrin binding; IDA:UniProtKB.
DR   GO; GO:0015837; P:amine transport; NAS:UniProtKB.
DR   GO; GO:0072488; P:ammonium transmembrane transport; IDA:GOC.
DR   GO; GO:0015696; P:ammonium transport; IDA:UniProtKB.
DR   GO; GO:0006873; P:cellular ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0070634; P:transepithelial ammonium transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   RHDF1_HUMAN             Reviewed;         855 AA.
AC   Q96CC6; Q04842; Q1W6H2; Q4TT59; Q96S34; Q9H6E1;
DE   RecName: Full=Inactive rhomboid protein 1;
DE            Short=iRhom1;
DE   AltName: Full=Epidermal growth factor receptor-related protein;
DE   AltName: Full=Rhomboid 5 homolog 1;
DE   AltName: Full=Rhomboid family member 1;
DE   AltName: Full=p100hRho;
GN   Name=RHBDF1; Synonyms=C16orf8, DIST1, IRHOM1;
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   GO; GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0050708; P:regulation of protein secretion; IMP:UniProtKB.
//
ID   RHDF2_HUMAN             Reviewed;         856 AA.
AC   Q6PJF5; A6NEM3; A8K801; Q5U607; Q5YGQ8; Q9H6E9;
DE   RecName: Full=Inactive rhomboid protein 2;
DE            Short=iRhom2;
DE   AltName: Full=Rhomboid 5 homolog 2;
DE   AltName: Full=Rhomboid family member 2;
DE   AltName: Full=Rhomboid veinlet-like protein 5;
DE   AltName: Full=Rhomboid veinlet-like protein 6;
GN   Name=RHBDF2; Synonyms=IRHOM2, RHBDL5, RHBDL6;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0050709; P:negative regulation of protein secretion; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RHD_HUMAN               Reviewed;         417 AA.
AC   Q02161; Q02162; Q07618; Q16147; Q16235; Q16355; Q5VSK0; Q5XLS9;
AC   Q5XLT1; Q5XLT2; Q9NPK0; Q9UQ20; Q9UQ21; Q9UQ22; Q9UQ23;
DE   RecName: Full=Blood group Rh(D) polypeptide;
DE   AltName: Full=RHXIII;
DE   AltName: Full=Rh polypeptide 2;
DE            Short=RhPII;
DE   AltName: Full=Rhesus D antigen;
DE   AltName: CD_antigen=CD240D;
GN   Name=RHD;
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
//
ID   RHEB_HUMAN              Reviewed;         184 AA.
AC   Q15382; B3KWN6; D3DX13; Q53Y56; Q99444;
DE   RecName: Full=GTP-binding protein Rheb;
DE   AltName: Full=Ras homolog enriched in brain;
DE   Flags: Precursor;
GN   Name=RHEB; Synonyms=RHEB2;
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; ISS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RHES_HUMAN              Reviewed;         266 AA.
AC   Q96D21; O95520; Q5THY8;
DE   RecName: Full=GTP-binding protein Rhes;
DE   AltName: Full=Ras homolog enriched in striatum;
DE   AltName: Full=Tumor endothelial marker 2;
DE   Flags: Precursor;
GN   Name=RASD2; Synonyms=TEM2;
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IPI:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; ISS:UniProtKB.
DR   GO; GO:0043949; P:regulation of cAMP-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IC:UniProtKB.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Ensembl.
//
ID   RHG01_HUMAN             Reviewed;         439 AA.
AC   Q07960; D3DQQ6;
DE   RecName: Full=Rho GTPase-activating protein 1;
DE   AltName: Full=CDC42 GTPase-activating protein;
DE   AltName: Full=GTPase-activating protein rhoOGAP;
DE   AltName: Full=Rho-related small GTPase protein activator;
DE   AltName: Full=Rho-type GTPase-activating protein 1;
DE   AltName: Full=p50-RhoGAP;
GN   Name=ARHGAP1; Synonyms=CDC42GAP, RHOGAP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:MGI.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
//
ID   RHF2B_HUMAN             Reviewed;         288 AA.
AC   P0C7M4;
DE   RecName: Full=Rhox homeobox family member 2B;
GN   Name=RHOXF2B;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   RHG04_HUMAN             Reviewed;         946 AA.
AC   P98171; Q14144; Q86UY3;
DE   RecName: Full=Rho GTPase-activating protein 4;
DE   AltName: Full=Rho-GAP hematopoietic protein C1;
DE   AltName: Full=Rho-type GTPase-activating protein 4;
DE   AltName: Full=p115;
GN   Name=ARHGAP4; Synonyms=KIAA0131, RGC1, RHOGAP4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0010764; P:negative regulation of fibroblast migration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG05_HUMAN             Reviewed;        1502 AA.
AC   Q13017; A1L375; A1L376; A8KAA1; D3DS89; D3DS90; Q05BE8; Q05BU8;
AC   Q59ER0; Q6DHZ3;
DE   RecName: Full=Rho GTPase-activating protein 5;
DE   AltName: Full=Rho-type GTPase-activating protein 5;
DE   AltName: Full=p190-B;
GN   Name=ARHGAP5; Synonyms=RHOGAP5;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG06_HUMAN             Reviewed;         974 AA.
AC   O43182; B2RWQ0; O43437; Q9P1B3; Q9UK81; Q9UK82;
DE   RecName: Full=Rho GTPase-activating protein 6;
DE   AltName: Full=Rho-type GTPase-activating protein 6;
DE   AltName: Full=Rho-type GTPase-activating protein RhoGAPX-1;
GN   Name=ARHGAP6; Synonyms=RHOGAP6;
DR   GO; GO:0016004; F:phospholipase activator activity; IDA:BHF-UCL.
DR   GO; GO:0043274; F:phospholipase binding; IPI:BHF-UCL.
DR   GO; GO:0005100; F:Rho GTPase activator activity; ISS:BHF-UCL.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0030041; P:actin filament polymerization; NAS:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; IDA:BHF-UCL.
DR   GO; GO:0048041; P:focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; IMP:BHF-UCL.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IMP:BHF-UCL.
DR   GO; GO:0010518; P:positive regulation of phospholipase activity; IDA:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0043087; P:regulation of GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG07_HUMAN             Reviewed;        1528 AA.
AC   Q96QB1; B4DR10; B8PTI0; E9PDZ8; E9PF76; E9PGY9; O14868; O43199;
AC   Q7Z5R8; Q86UC6; Q9C0E0; Q9H7A2;
DE   RecName: Full=Rho GTPase-activating protein 7;
DE   AltName: Full=Deleted in liver cancer 1 protein;
DE            Short=DLC-1;
DE   AltName: Full=HP protein;
DE   AltName: Full=Rho-type GTPase-activating protein 7;
DE   AltName: Full=START domain-containing protein 12;
DE            Short=StARD12;
DE   AltName: Full=StAR-related lipid transfer protein 12;
GN   Name=DLC1; Synonyms=ARHGAP7, KIAA1723, STARD12;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; ISS:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021575; P:hindbrain morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:1900119; P:positive regulation of execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG09_HUMAN             Reviewed;         750 AA.
AC   Q9BRR9; B4DVI3; E9PDX9; Q8NAF3; Q8TCJ3; Q8WYR0; Q96EZ2; Q96S74;
DE   RecName: Full=Rho GTPase-activating protein 9;
DE   AltName: Full=Rho-type GTPase-activating protein 9;
GN   Name=ARHGAP9;
DR   GO; GO:0005096; F:GTPase activator activity; IDA:MGI.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG10_HUMAN             Reviewed;         786 AA.
AC   A1A4S6; A1L0S5; Q2VPC4; Q2VPC5; Q96EV3; Q96S75;
DE   RecName: Full=Rho GTPase-activating protein 10;
DE   AltName: Full=GTPase regulator associated with focal adhesion kinase 2;
DE   AltName: Full=Graf-related protein 2;
DE   AltName: Full=Rho-type GTPase-activating protein 10;
GN   Name=ARHGAP10; Synonyms=GRAF2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG08_HUMAN             Reviewed;         464 AA.
AC   P85298; A6ZJ79; A6ZJ80; O75983; O95695; Q96RW1; Q96RW2; Q9HA49;
AC   Q9HC46; Q9NSG0; Q9NVX8; Q9NXL1; Q9UH20;
DE   RecName: Full=Rho GTPase-activating protein 8;
DE   AltName: Full=Rho-type GTPase-activating protein 8;
GN   Name=ARHGAP8;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG12_HUMAN             Reviewed;         846 AA.
AC   Q8IWW6; B1ANY0; B1ANY1; B1ANY2; Q504X1; Q86UB3; Q8IWW7; Q8N3L1;
AC   Q9NT76;
DE   RecName: Full=Rho GTPase-activating protein 12;
DE   AltName: Full=Rho-type GTPase-activating protein 12;
GN   Name=ARHGAP12;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG15_HUMAN             Reviewed;         475 AA.
AC   Q53QZ3; Q53R36; Q53RD7; Q53RT6; Q53SX9; Q584N9; Q6PJE6; Q86WP1;
AC   Q8IXX1; Q9NRL8; Q9NZ77; Q9NZ91;
DE   RecName: Full=Rho GTPase-activating protein 15;
DE   AltName: Full=ArhGAP15;
DE   AltName: Full=Rho-type GTPase-activating protein 15;
GN   Name=ARHGAP15; ORFNames=BM-024, BM-030, BM-046;
DR   GO; GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:GOC.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:MGI.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG17_HUMAN             Reviewed;         881 AA.
AC   Q68EM7; A8K6M6; Q6ZUS4; Q7Z2F2; Q8NDG2; Q96KS2; Q96KS3; Q96SS8;
AC   Q9BVF6; Q9H8U5; Q9NW54;
DE   RecName: Full=Rho GTPase-activating protein 17;
DE   AltName: Full=Rho-type GTPase-activating protein 17;
DE   AltName: Full=RhoGAP interacting with CIP4 homologs protein 1;
DE            Short=RICH-1;
GN   Name=ARHGAP17; Synonyms=RICH1; ORFNames=MSTP066, MSTP110;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG18_HUMAN             Reviewed;         663 AA.
AC   Q8N392; E1P575; Q58EZ3; Q6P679; Q6PJD7; Q96S64;
DE   RecName: Full=Rho GTPase-activating protein 18;
DE   AltName: Full=MacGAP;
DE   AltName: Full=Rho-type GTPase-activating protein 18;
GN   Name=ARHGAP18;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG19_HUMAN             Reviewed;         494 AA.
AC   Q14CB8; A1XCP1; B4DZR1; Q14CF2; Q5J8M2; Q5T460; Q5T462; Q68DG6;
AC   Q8N9X1; Q8NF34; Q8TEK1;
DE   RecName: Full=Rho GTPase-activating protein 19;
DE   AltName: Full=Rho-type GTPase-activating protein 19;
GN   Name=ARHGAP19;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG20_HUMAN             Reviewed;        1191 AA.
AC   Q9P2F6; A8K8C5; B0YIW7; B0YIW8; Q6RJU1; Q6RJU2; Q6RJU3; Q6RJU5;
AC   Q8IXS1;
DE   RecName: Full=Rho GTPase-activating protein 20;
DE   AltName: Full=Rho-type GTPase-activating protein 20;
GN   Name=ARHGAP20; Synonyms=KIAA1391;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG21_HUMAN             Reviewed;        1957 AA.
AC   Q5T5U3; Q0VF98; Q7Z3P7; Q8N3A2; Q8NI19; Q8TBV5; Q9P2C3;
DE   RecName: Full=Rho GTPase-activating protein 21;
DE   AltName: Full=Rho GTPase-activating protein 10;
DE   AltName: Full=Rho-type GTPase-activating protein 21;
GN   Name=ARHGAP21; Synonyms=ARHGAP10, KIAA1424;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051683; P:establishment of Golgi localization; IDA:BHF-UCL.
DR   GO; GO:0007030; P:Golgi organization; IMP:BHF-UCL.
DR   GO; GO:0051684; P:maintenance of Golgi location; IMP:BHF-UCL.
DR   GO; GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RHG22_HUMAN             Reviewed;         698 AA.
AC   Q7Z5H3; A0AVP7; A5YM75; B4DED8; B9EGA0; C9JDM2; O00152; Q6ZSB0;
DE   RecName: Full=Rho GTPase-activating protein 22;
DE   AltName: Full=Rho-type GTPase-activating protein 22;
GN   Name=ARHGAP22; Synonyms=RHOGAP2;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RHG23_HUMAN             Reviewed;        1491 AA.
AC   Q9P227;
DE   RecName: Full=Rho GTPase-activating protein 23;
DE   AltName: Full=Rho-type GTPase-activating protein 23;
GN   Name=ARHGAP23; Synonyms=KIAA1501;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG24_HUMAN             Reviewed;         748 AA.
AC   Q8N264; Q4KMG1; Q6ZNV3; Q86TI5; Q86WE4; Q9H0T6;
DE   RecName: Full=Rho GTPase-activating protein 24;
DE   AltName: Full=Filamin-A-associated RhoGAP;
DE            Short=FilGAP;
DE   AltName: Full=RAC1- and CDC42-specific GTPase-activating protein of 72 kDa;
DE            Short=RC-GAP72;
DE   AltName: Full=Rho-type GTPase-activating protein 24;
DE   AltName: Full=RhoGAP of 73 kDa;
DE   AltName: Full=Sarcoma antigen NY-SAR-88;
DE   AltName: Full=p73RhoGAP;
GN   Name=ARHGAP24; Synonyms=FILGAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0035021; P:negative regulation of Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:1900028; P:negative regulation of ruffle assembly; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0035313; P:wound healing, spreading of epidermal cells; IEA:Ensembl.
//
ID   RHG25_HUMAN             Reviewed;         645 AA.
AC   P42331; A8K2Y1; B7Z498; E9PFQ7; G5E9G2; Q8IXQ2;
DE   RecName: Full=Rho GTPase-activating protein 25;
DE   AltName: Full=Rho-type GTPase-activating protein 25;
GN   Name=ARHGAP25; Synonyms=KIAA0053;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG26_HUMAN             Reviewed;         814 AA.
AC   Q9UNA1; O75117; Q5D035; Q9BYS6; Q9BYS7; Q9UJ00;
DE   RecName: Full=Rho GTPase-activating protein 26;
DE   AltName: Full=GTPase regulator associated with focal adhesion kinase;
DE   AltName: Full=Oligophrenin-1-like protein;
DE   AltName: Full=Rho-type GTPase-activating protein 26;
GN   Name=ARHGAP26; Synonyms=GRAF, KIAA0621, OPHN1L;
DR   GO; GO:0005543; F:phospholipid binding; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; NAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG27_HUMAN             Reviewed;         889 AA.
AC   Q6ZUM4; A4FU35; A8K3N5; C9JTF3; Q494U0; Q6NWZ8; Q8WY58;
DE   RecName: Full=Rho GTPase-activating protein 27;
DE   AltName: Full=CIN85-associated multi-domain-containing Rho GTPase-activating protein 1;
DE   AltName: Full=Rho-type GTPase-activating protein 27;
DE   AltName: Full=SH3 domain-containing protein 20;
GN   Name=ARHGAP27; Synonyms=CAMGAP1, SH3D20; ORFNames=PP905;
DR   GO; GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:HGNC.
DR   GO; GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; ISS:GOC.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RHG28_HUMAN             Reviewed;         729 AA.
AC   Q9P2N2; A8MQB7; A8MU88; Q6P160; Q8N4T3; Q9NW53;
DE   RecName: Full=Rho GTPase-activating protein 28;
DE   AltName: Full=Rho-type GTPase-activating protein 28;
GN   Name=ARHGAP28; Synonyms=KIAA1314;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG29_HUMAN             Reviewed;        1261 AA.
AC   Q52LW3; O15463; Q59H86; Q5VYZ0; Q6NVX2; Q8TBI6;
DE   RecName: Full=Rho GTPase-activating protein 29;
DE   AltName: Full=PTPL1-associated RhoGAP protein 1;
DE   AltName: Full=Rho-type GTPase-activating protein 29;
GN   Name=ARHGAP29; Synonyms=PARG1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:MGI.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG30_HUMAN             Reviewed;        1101 AA.
AC   Q7Z6I6; Q5SY52; Q5SY53; Q5SY54; Q6ZML6; Q7Z3J8; Q86XI7;
DE   RecName: Full=Rho GTPase-activating protein 30;
DE   AltName: Full=Rho-type GTPase-activating protein 30;
GN   Name=ARHGAP30;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG32_HUMAN             Reviewed;        2087 AA.
AC   A7KAX9; I7H0B0; O94820; Q86YL6; Q8IUG4; Q9BWG3;
DE   RecName: Full=Rho GTPase-activating protein 32;
DE   AltName: Full=Brain-specific Rho GTPase-activating protein;
DE   AltName: Full=GAB-associated Cdc42/Rac GTPase-activating protein;
DE   AltName: Full=GC-GAP;
DE   AltName: Full=GTPase regulator interacting with TrkA;
DE   AltName: Full=Rho-type GTPase-activating protein 32;
DE   AltName: Full=Rho/Cdc42/Rac GTPase-activating protein RICS;
DE   AltName: Full=RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling;
DE   AltName: Full=p200RhoGAP;
DE   AltName: Full=p250GAP;
GN   Name=ARHGAP32; Synonyms=GRIT, KIAA0712, RICS;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG33_HUMAN             Reviewed;        1287 AA.
AC   O14559; O14552; O14560; Q6ZSP6; Q96CP3; Q9NT23;
DE   RecName: Full=Rho GTPase-activating protein 33;
DE   AltName: Full=Rho-type GTPase-activating protein 33;
DE   AltName: Full=Sorting nexin-26;
DE   AltName: Full=Tc10/CDC42 GTPase-activating protein;
GN   Name=ARHGAP33; Synonyms=SNX26, TCGAP;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG31_HUMAN             Reviewed;        1444 AA.
AC   Q2M1Z3; Q9ULL6;
DE   RecName: Full=Rho GTPase-activating protein 31;
DE   AltName: Full=Cdc42 GTPase-activating protein;
GN   Name=ARHGAP31; Synonyms=CDGAP, KIAA1204;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG35_HUMAN             Reviewed;        1499 AA.
AC   Q9NRY4; A7E2A4; Q14452; Q9C0E1;
DE   RecName: Full=Rho GTPase-activating protein 35;
DE   AltName: Full=Glucocorticoid receptor DNA-binding factor 1;
DE   AltName: Full=Glucocorticoid receptor repression factor 1;
DE            Short=GRF-1;
DE   AltName: Full=Rho GAP p190A;
DE            Short=p190-A;
GN   Name=ARHGAP35; Synonyms=GRF1, GRLF1, KIAA1722;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:Reactome.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   RHG36_HUMAN             Reviewed;         547 AA.
AC   Q6ZRI8; B7Z234; B7Z439; Q5JRL9; Q5JRM0; Q5JRM1; Q96NU6;
DE   RecName: Full=Rho GTPase-activating protein 36;
DE   Flags: Precursor;
GN   Name=ARHGAP36;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG40_HUMAN             Reviewed;         622 AA.
AC   Q5TG30;
DE   RecName: Full=Rho GTPase-activating protein 40;
DE   AltName: Full=Rho-type GTPase-activating protein 40;
GN   Name=ARHGAP40; Synonyms=C20orf95;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG39_HUMAN             Reviewed;        1083 AA.
AC   Q9C0H5; B4E1I1;
DE   RecName: Full=Rho GTPase-activating protein 39;
GN   Name=ARHGAP39; Synonyms=KIAA1688;
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHG42_HUMAN             Reviewed;         874 AA.
AC   A6NI28; Q96M56;
DE   RecName: Full=Rho GTPase-activating protein 42;
DE   AltName: Full=Rho GTPase-activating protein 10-like;
DE   AltName: Full=Rho-type GTPase-activating protein 42;
GN   Name=ARHGAP42;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RHG44_HUMAN             Reviewed;         818 AA.
AC   Q17R89; A8MQB2; O75160; Q7Z5Z7; Q9Y4Q4;
DE   RecName: Full=Rho GTPase-activating protein 44;
DE   AltName: Full=NPC-A-10;
DE   AltName: Full=Rho-type GTPase-activating protein RICH2;
DE   AltName: Full=RhoGAP interacting with CIP4 homologs protein 2;
DE            Short=RICH-2;
GN   Name=ARHGAP44; Synonyms=KIAA0672, RICH2;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005543; F:phospholipid binding; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHGBA_HUMAN             Reviewed;        1023 AA.
AC   Q6P4F7; Q6PI96; Q9Y3S6;
DE   RecName: Full=Rho GTPase-activating protein 11A;
DE   AltName: Full=Rho-type GTPase-activating protein 11A;
GN   Name=ARHGAP11A; Synonyms=KIAA0013;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHGBB_HUMAN             Reviewed;         267 AA.
AC   Q3KRB8;
DE   RecName: Full=Rho GTPase-activating protein 11B;
DE   AltName: Full=Rho-type GTPase-activating protein 11B;
GN   Name=ARHGAP11B;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHN2P_HUMAN             Reviewed;         583 AA.
AC   A8MT19;
DE   RecName: Full=Putative rhophilin-2-like protein RHPN2P1;
DE   AltName: Full=Rhophilin-2 pseudogene 1;
GN   Name=RHPN2P1;
//
ID   RHNO1_HUMAN             Reviewed;         238 AA.
AC   Q9BSD3; B7Z989;
DE   RecName: Full=RAD9, HUS1, RAD1-interacting nuclear orphan protein 1;
DE   AltName: Full=RAD9, RAD1, HUS1-interacting nuclear orphan protein;
GN   Name=RHNO1; Synonyms=C12orf32, RHINO; ORFNames=HKMT1188;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0070318; P:positive regulation of G0 to G1 transition; IMP:UniProtKB.
DR   GO; GO:0000725; P:recombinational repair; IMP:UniProtKB.
//
ID   RHOC_HUMAN              Reviewed;         193 AA.
AC   P08134; B3KSW1; Q6ICN3;
DE   RecName: Full=Rho-related GTP-binding protein RhoC;
DE   AltName: Full=Rho cDNA clone 9;
DE            Short=h9;
DE   Flags: Precursor;
GN   Name=RHOC; Synonyms=ARH9, ARHC;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043297; P:apical junction assembly; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOB_HUMAN              Reviewed;         196 AA.
AC   P62745; B2R692; P01121; Q5U0H6; Q7RTN5; Q7RTR9; Q9CUV7;
DE   RecName: Full=Rho-related GTP-binding protein RhoB;
DE   AltName: Full=Rho cDNA clone 6;
DE            Short=h6;
DE   Flags: Precursor;
GN   Name=RHOB; Synonyms=ARH6, ARHB;
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; TAS:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006927; P:transformed cell apoptotic process; ISS:UniProtKB.
//
ID   RHOA_HUMAN              Reviewed;         193 AA.
AC   P61586; P06749; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4;
DE   RecName: Full=Transforming protein RhoA;
DE   AltName: Full=Rho cDNA clone 12;
DE            Short=h12;
DE   Flags: Precursor;
GN   Name=RHOA; Synonyms=ARH12, ARHA, RHO12;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:UniProtKB.
DR   GO; GO:0017022; F:myosin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0043297; P:apical junction assembly; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0036089; P:cleavage furrow formation; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043931; P:ossification involved in bone maturation; ISS:BHF-UCL.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IMP:MGI.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; NAS:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0033688; P:regulation of osteoblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IMP:BHF-UCL.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0061383; P:trabecula morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RHOD_HUMAN              Reviewed;         210 AA.
AC   O00212;
DE   RecName: Full=Rho-related GTP-binding protein RhoD;
DE   AltName: Full=Rho-related protein HP1;
DE            Short=RhoHP1;
DE   Flags: Precursor;
GN   Name=RHOD; Synonyms=ARHD;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOH_HUMAN              Reviewed;         191 AA.
AC   Q15669;
DE   RecName: Full=Rho-related GTP-binding protein RhoH;
DE   AltName: Full=GTP-binding protein TTF;
DE   AltName: Full=Translocation three four protein;
DE   Flags: Precursor;
GN   Name=RHOH; Synonyms=ARHH, TTF;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0005095; F:GTPase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0019210; F:kinase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017048; F:Rho GTPase binding; NAS:UniProtKB.
DR   GO; GO:0045576; P:mast cell activation; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IDA:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0030217; P:T cell differentiation; NAS:UniProtKB.
//
ID   RHOG_HUMAN              Reviewed;         191 AA.
AC   P84095; P35238; Q8NI04;
DE   RecName: Full=Rho-related GTP-binding protein RhoG;
DE   Flags: Precursor;
GN   Name=RHOG; Synonyms=ARHG;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:MGI.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0016601; P:Rac protein signal transduction; IDA:MGI.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:MGI.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOV_HUMAN              Reviewed;         236 AA.
AC   Q96L33; Q2KHQ5; Q8TDW6;
DE   RecName: Full=Rho-related GTP-binding protein RhoV;
DE   AltName: Full=CDC42-like GTPase 2;
DE   AltName: Full=GTP-binding protein-like 2;
DE   AltName: Full=Rho GTPase-like protein ARHV;
DE   AltName: Full=Wnt-1 responsive Cdc42 homolog 2;
DE            Short=WRCH-2;
GN   Name=RHOV; Synonyms=ARHV, WRCH2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOU_HUMAN              Reviewed;         258 AA.
AC   Q7L0Q8; B1AKN1; Q59FE9; Q8TDQ2;
DE   RecName: Full=Rho-related GTP-binding protein RhoU;
DE   AltName: Full=CDC42-like GTPase 1;
DE   AltName: Full=GTP-binding protein-like 1;
DE   AltName: Full=Rho GTPase-like protein ARHU;
DE   AltName: Full=Ryu GTPase;
DE   AltName: Full=Wnt-1 responsive Cdc42 homolog 1;
DE            Short=WRCH-1;
GN   Name=RHOU; Synonyms=ARHU, CDC42L1, G28K, WRCH1; ORFNames=SB128;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016601; P:Rac protein signal transduction; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOF_HUMAN              Reviewed;         211 AA.
AC   Q9HBH0; Q8WVB1; Q9NXH6;
DE   RecName: Full=Rho-related GTP-binding protein RhoF;
DE   AltName: Full=Rho family GTPase Rif;
DE   AltName: Full=Rho in filopodia;
DE   Flags: Precursor;
GN   Name=RHOF; Synonyms=ARHF, RIF;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOQ_HUMAN              Reviewed;         205 AA.
AC   P17081; D6W5A6; Q0VGN1; Q52LS8; Q53SJ1; Q6NS39; Q6P146; Q7Z480;
DE   RecName: Full=Rho-related GTP-binding protein RhoQ;
DE   AltName: Full=Ras-like protein TC10;
DE   AltName: Full=Ras-like protein family member 7A;
DE   Flags: Precursor;
GN   Name=RHOQ; Synonyms=ARHQ, RASL7A, TC10;
DR   GO; GO:0032427; F:GBD domain binding; IPI:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0005522; F:profilin binding; IPI:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IMP:BHF-UCL.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:BHF-UCL.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IC:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHOJ_HUMAN              Reviewed;         214 AA.
AC   Q9H4E5; Q96KC1;
DE   RecName: Full=Rho-related GTP-binding protein RhoJ;
DE   AltName: Full=Ras-like protein family member 7B;
DE   AltName: Full=Tc10-like GTP-binding protein;
DE   Flags: Precursor;
GN   Name=RHOJ; Synonyms=ARHJ, RASL7B, RHOI, TCL;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RHPN1_HUMAN             Reviewed;         695 AA.
AC   Q8TCX5; Q8TAV1; Q96PV9;
DE   RecName: Full=Rhophilin-1;
DE   AltName: Full=GTP-Rho-binding protein 1;
GN   Name=RHPN1; Synonyms=KIAA1929;
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RHPN2_HUMAN             Reviewed;         686 AA.
AC   Q8IUC4; B2RCG8; B3KUY8; Q8N3T7; Q8N9D6; Q8NE33; Q96RU1;
DE   RecName: Full=Rhophilin-2;
DE   AltName: Full=76 kDa RhoB effector protein;
DE   AltName: Full=GTP-Rho-binding protein 2;
DE   AltName: Full=p76RBE;
GN   Name=RHPN2;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RHXF1_HUMAN             Reviewed;         184 AA.
AC   Q8NHV9; O95030; Q3SYE0;
DE   RecName: Full=Rhox homeobox family member 1;
DE   AltName: Full=Ovary-, testis- and epididymis-expressed gene protein;
DE   AltName: Full=Paired-like homeobox protein PEPP-1;
GN   Name=RHOXF1; Synonyms=OTEX, PEPP1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007276; P:gamete generation; NAS:UniProtKB.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0019953; P:sexual reproduction; IEP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RHXF2_HUMAN             Reviewed;         288 AA.
AC   Q9BQY4; Q9BR00;
DE   RecName: Full=Rhox homeobox family member 2;
DE   AltName: Full=Paired-like homeobox protein PEPP-2;
DE   AltName: Full=Testis homeobox gene 1;
GN   Name=RHOXF2; Synonyms=PEPP2, THG1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   RIAD1_HUMAN             Reviewed;          92 AA.
AC   A6NNX1;
DE   RecName: Full=RIIa domain-containing protein 1;
GN   Name=RIIAD1; Synonyms=C1orf230;
//
ID   RIBC1_HUMAN             Reviewed;         379 AA.
AC   Q8N443; B4E297; E9PDU2; Q5H931; Q96A80;
DE   RecName: Full=RIB43A-like with coiled-coils protein 1;
GN   Name=RIBC1;
//
ID   RIBC2_HUMAN             Reviewed;         309 AA.
AC   Q9H4K1; Q6ICD0; Q9Y413;
DE   RecName: Full=RIB43A-like with coiled-coils protein 2;
GN   Name=RIBC2; Synonyms=C22orf11;
//
ID   RIC1_HUMAN              Reviewed;        1423 AA.
AC   Q4ADV7; B2RN24; B7ZM67; G5E932; Q4VXJ8; Q4VXJ9; Q76MT5; Q8N6E0;
AC   Q8TEH4; Q9H0A5; Q9H9S1;
DE   RecName: Full=Protein RIC1 homolog;
DE   AltName: Full=Connexin-43-interacting protein of 150 kDa;
GN   Name=KIAA1432; Synonyms=CIP150;
//
ID   RIC3_HUMAN              Reviewed;         369 AA.
AC   Q7Z5B4; B0B1U0; B2RD25; D3DQU5; Q6UX78; Q7Z5B3; Q86T94; Q8TBJ9;
AC   Q9HAH8;
DE   RecName: Full=Protein RIC-3;
DE   AltName: Full=Resistant to inhibitor of cholinesterase 3;
DE   Flags: Precursor;
GN   Name=RIC3; ORFNames=UNQ720/PRO1385;
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IEA:Ensembl.
//
ID   RIC8A_HUMAN             Reviewed;         531 AA.
AC   Q9NPQ8; Q0P508; Q2T9J1; Q7Z352; Q96EZ1; Q96SZ2; Q9H064; Q9H5H3;
AC   Q9H9E7;
DE   RecName: Full=Synembryn-A;
DE   AltName: Full=Protein Ric-8A;
GN   Name=RIC8A;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0071711; P:basement membrane organization; IEA:Ensembl.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0070586; P:cell-cell adhesion involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   RIC8B_HUMAN             Reviewed;         520 AA.
AC   Q9NVN3; A2RTZ0; Q4G103; Q6ZRN4; Q86WD3;
DE   RecName: Full=Synembryn-B;
DE   AltName: Full=Brain synembryn;
DE            Short=hSyn;
DE   AltName: Full=Protein Ric-8B;
GN   Name=RIC8B;
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; IDA:MGI.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:MGI.
//
ID   RICTR_HUMAN             Reviewed;        1708 AA.
AC   Q6R327; B2RNX0; B7ZMF7; Q68DT5; Q86UB7; Q8N3A0; Q8NCM6;
DE   RecName: Full=Rapamycin-insensitive companion of mTOR;
DE   AltName: Full=AVO3 homolog;
DE            Short=hAVO3;
GN   Name=RICTOR; Synonyms=KIAA1999;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0031929; P:TOR signaling; IEA:InterPro.
//
ID   RIF1_HUMAN              Reviewed;        2472 AA.
AC   Q5UIP0; A6NC27; C9JBR1; Q5H9R3; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94;
AC   Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4;
DE   RecName: Full=Telomere-associated protein RIF1;
DE   AltName: Full=Rap1-interacting factor 1 homolog;
GN   Name=RIF1;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   RIFK_HUMAN              Reviewed;         155 AA.
AC   Q969G6; Q5JSG9; Q9NUT7;
DE   RecName: Full=Riboflavin kinase;
DE            EC=2.7.1.26;
DE   AltName: Full=ATP:riboflavin 5'-phosphotransferase;
DE   AltName: Full=Flavokinase;
GN   Name=RFK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008531; F:riboflavin kinase activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IMP:MGI.
DR   GO; GO:0009398; P:FMN biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0033864; P:positive regulation of NAD(P)H oxidase activity; IMP:MGI.
DR   GO; GO:0009231; P:riboflavin biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006771; P:riboflavin metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   RIG_HUMAN               Reviewed;         110 AA.
AC   Q13278;
DE   RecName: Full=Putative protein RIG;
DE   AltName: Full=Protein regulated in glioma;
GN   Name=RIG;
//
ID   RILP_HUMAN              Reviewed;         401 AA.
AC   Q96NA2; B2RBQ8; Q71RE6; Q9BSL3; Q9BYS3;
DE   RecName: Full=Rab-interacting lysosomal protein;
GN   Name=RILP; ORFNames=PP10141;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; TAS:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; NAS:UniProtKB.
//
ID   RIM3A_HUMAN             Reviewed;        1639 AA.
AC   Q9UFD9; Q8IYP7; Q9BY94; Q9UFQ5;
DE   RecName: Full=RIMS-binding protein 3A;
DE            Short=RIM-BP3.A;
DE   AltName: Full=RIMS-binding protein 3.1;
DE            Short=RIM-BP3.1;
GN   Name=RIMBP3; Synonyms=KIAA1666, RIMBP3A;
//
ID   RIM3C_HUMAN             Reviewed;        1639 AA.
AC   A6NJZ7;
DE   RecName: Full=RIMS-binding protein 3C;
DE            Short=RIM-BP3.C;
DE   AltName: Full=RIMS-binding protein 3.3;
DE            Short=RIM-BP3.3;
GN   Name=RIMBP3C;
//
ID   RIM3B_HUMAN             Reviewed;        1639 AA.
AC   A6NNM3;
DE   RecName: Full=RIMS-binding protein 3B;
DE            Short=RIM-BP3.B;
DE   AltName: Full=RIMS-binding protein 3.2;
DE            Short=RIM-BP3.2;
GN   Name=RIMBP3B;
//
ID   RIMB1_HUMAN             Reviewed;        1857 AA.
AC   O95153; O75111; Q8N5W3;
DE   RecName: Full=Peripheral-type benzodiazepine receptor-associated protein 1;
DE            Short=PRAX-1;
DE   AltName: Full=Peripheral benzodiazepine receptor-interacting protein;
DE            Short=PBR-IP;
DE   AltName: Full=RIMS-binding protein 1;
DE            Short=RIM-BP1;
GN   Name=BZRAP1; Synonyms=KIAA0612, RBP1, RIMBP1;
DR   GO; GO:0030156; F:benzodiazepine receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RIMB2_HUMAN             Reviewed;        1052 AA.
AC   O15034; Q96ID2;
DE   RecName: Full=RIMS-binding protein 2;
DE            Short=RIM-BP2;
GN   Name=RIMBP2; Synonyms=KIAA0318, RBP2;
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   RIMKA_HUMAN             Reviewed;         391 AA.
AC   Q8IXN7; Q5VUS5;
DE   RecName: Full=N-acetylaspartylglutamate synthase A;
DE            Short=NAAG synthetase A;
DE            Short=NAAGS;
DE            EC=6.3.2.41;
DE   AltName: Full=N-acetylaspartylglutamylglutamate synthase A;
DE            EC=6.3.2.42;
DE   AltName: Full=Ribosomal protein S6 modification-like protein A;
GN   Name=RIMKLA; Synonyms=FAM80A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0072590; F:N-acetyl-L-aspartate-L-glutamate ligase activity; ISS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   RIMKB_HUMAN             Reviewed;         386 AA.
AC   Q9ULI2; B7Z834; D3DUV2; Q8N4P4; Q8WTW6;
DE   RecName: Full=Beta-citrylglutamate synthase B;
DE            EC=6.3.1.17;
DE   AltName: Full=N-acetyl-aspartylglutamate synthetase B;
DE            Short=NAAG synthetase B;
DE            Short=NAAGS;
DE            EC=6.3.2.41;
DE   AltName: Full=Ribosomal protein S6 modification-like protein B;
GN   Name=RIMKLB; Synonyms=FAM80B, KIAA1238;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0072591; F:citrate-L-glutamate ligase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0072590; F:N-acetyl-L-aspartate-L-glutamate ligase activity; ISS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   RIMS1_HUMAN             Reviewed;        1692 AA.
AC   Q86UR5; A7MBN6; B7Z2M0; B7Z2Q9; B7Z3S3; B7Z6S2; E7EX08; E9PCB7;
AC   E9PCZ1; E9PF48; E9PHF5; E9PHR1; O15048; Q5JY21; Q5JY25; Q5SZK1;
AC   Q8TDY9; Q8TDZ5; Q9HBA1; Q9HBA2; Q9HBA3; Q9HBA4; Q9HBA5; Q9HBA6;
DE   RecName: Full=Regulating synaptic membrane exocytosis protein 1;
DE   AltName: Full=Rab-3-interacting molecule 1;
DE            Short=RIM 1;
DE   AltName: Full=Rab-3-interacting protein 2;
GN   Name=RIMS1; Synonyms=KIAA0340, RAB3IP2, RIM1; ORFNames=Nbla00761;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:UniProtKB.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; TAS:UniProtKB.
DR   GO; GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IEA:Ensembl.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061025; P:membrane fusion; NAS:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0045055; P:regulated secretory pathway; NAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0046903; P:secretion; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RIMS2_HUMAN             Reviewed;        1411 AA.
AC   Q9UQ26; B3KX91; F8WD47; O43413; Q86XL9; Q8IWV9; Q8IWW1;
DE   RecName: Full=Regulating synaptic membrane exocytosis protein 2;
DE   AltName: Full=Rab-3-interacting molecule 2;
DE            Short=RIM 2;
DE   AltName: Full=Rab-3-interacting protein 3;
GN   Name=RIMS2; Synonyms=KIAA0751, RAB3IP3, RIM2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IEA:Ensembl.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
//
ID   RIMS3_HUMAN             Reviewed;         308 AA.
AC   Q9UJD0; D3DPV8; Q92511;
DE   RecName: Full=Regulating synaptic membrane exocytosis protein 3;
DE            Short=Nim3;
DE   AltName: Full=RIM3 gamma;
DE   AltName: Full=Rab-3-interacting molecule 3;
DE            Short=RIM 3;
GN   Name=RIMS3; Synonyms=KIAA0237;
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
//
ID   RIMS4_HUMAN             Reviewed;         269 AA.
AC   Q9H426; A4FU94; E1P613; Q3MI44; Q5JWT7;
DE   RecName: Full=Regulating synaptic membrane exocytosis protein 4;
DE   AltName: Full=RIM4 gamma;
DE   AltName: Full=Rab3-interacting molecule 4;
DE            Short=RIM 4;
GN   Name=RIMS4; Synonyms=C20orf190;
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
//
ID   RIN1_HUMAN              Reviewed;         783 AA.
AC   Q13671; O15010; Q00427; Q96CC8;
DE   RecName: Full=Ras and Rab interactor 1;
DE   AltName: Full=Ras inhibitor JC99;
DE   AltName: Full=Ras interaction/interference protein 1;
GN   Name=RIN1;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RIN2_HUMAN              Reviewed;         895 AA.
AC   Q8WYP3; Q00425; Q5TFT8; Q9BQL3; Q9H071;
DE   RecName: Full=Ras and Rab interactor 2;
DE   AltName: Full=Ras association domain family 4;
DE   AltName: Full=Ras inhibitor JC265;
DE   AltName: Full=Ras interaction/interference protein 2;
GN   Name=RIN2; Synonyms=RASSF4;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0050790; P:regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; NAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
//
ID   RIN3_HUMAN              Reviewed;         985 AA.
AC   Q8TB24; Q76LB3; Q8NF30; Q8TEE8; Q8WYP4; Q9H6A5; Q9HAG1;
DE   RecName: Full=Ras and Rab interactor 3;
DE   AltName: Full=Ras interaction/interference protein 3;
GN   Name=RIN3;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IMP:GOC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RING1_HUMAN             Reviewed;         406 AA.
AC   Q06587; A8JZZ0; Q5JP96; Q5SQW2; Q86V19;
DE   RecName: Full=E3 ubiquitin-protein ligase RING1;
DE            EC=6.3.2.-;
DE   AltName: Full=Polycomb complex protein RING1;
DE   AltName: Full=RING finger protein 1;
DE   AltName: Full=Really interesting new gene 1 protein;
GN   Name=RING1; Synonyms=RNF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RING2_HUMAN             Reviewed;         336 AA.
AC   Q99496; B2RBS7; Q5TEN1; Q5TEN2;
DE   RecName: Full=E3 ubiquitin-protein ligase RING2;
DE            EC=6.3.2.-;
DE   AltName: Full=Huntingtin-interacting protein 2-interacting protein 3;
DE            Short=HIP2-interacting protein 3;
DE   AltName: Full=Protein DinG;
DE   AltName: Full=RING finger protein 1B;
DE            Short=RING1b;
DE   AltName: Full=RING finger protein 2;
DE   AltName: Full=RING finger protein BAP-1;
GN   Name=RNF2; Synonyms=BAP1, DING, HIPI3, RING1B;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0036353; P:histone H2A-K119 monoubiquitination; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RINI_HUMAN              Reviewed;         461 AA.
AC   P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6;
DE   RecName: Full=Ribonuclease inhibitor;
DE   AltName: Full=Placental ribonuclease inhibitor;
DE            Short=Placental RNase inhibitor;
DE   AltName: Full=Ribonuclease/angiogenin inhibitor 1;
DE            Short=RAI;
GN   Name=RNH1; Synonyms=PRI, RNH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008428; F:ribonuclease inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; NAS:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0045765; P:regulation of angiogenesis; IDA:UniProtKB.
//
ID   RINL_HUMAN              Reviewed;         566 AA.
AC   Q6ZS11; B4DPG5;
DE   RecName: Full=Ras and Rab interactor-like protein;
GN   Name=RINL;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043087; P:regulation of GTPase activity; ISS:GOC.
//
ID   RINT1_HUMAN             Reviewed;         792 AA.
AC   Q6NUQ1; Q75MG9; Q75MH0; Q96IW8; Q9H229; Q9HAD9;
DE   RecName: Full=RAD50-interacting protein 1;
DE   AltName: Full=RAD50 interactor 1;
DE            Short=HsRINT-1;
DE            Short=RINT-1;
GN   Name=RINT1;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:HGNC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   RIOK1_HUMAN             Reviewed;         568 AA.
AC   Q9BRS2; B2RB28; Q8NDC8; Q96NV9;
DE   RecName: Full=Serine/threonine-protein kinase RIO1;
DE            EC=2.7.11.1;
DE   AltName: Full=RIO kinase 1;
GN   Name=RIOK1;
DR   GuidetoPHARMACOLOGY; 2186; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   RIOK2_HUMAN             Reviewed;         552 AA.
AC   Q9BVS4; D6RDI3; Q9NUT0;
DE   RecName: Full=Serine/threonine-protein kinase RIO2;
DE            EC=2.7.11.1;
DE   AltName: Full=RIO kinase 2;
GN   Name=RIOK2;
DR   GuidetoPHARMACOLOGY; 2187; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   RIOK3_HUMAN             Reviewed;         519 AA.
AC   O14730; Q8IXN9;
DE   RecName: Full=Serine/threonine-protein kinase RIO3;
DE            EC=2.7.11.1;
DE   AltName: Full=RIO kinase 3;
DE   AltName: Full=sudD homolog;
GN   Name=RIOK3; Synonyms=SUDD;
DR   GuidetoPHARMACOLOGY; 2188; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; TAS:ProtInc.
//
ID   RIPK1_HUMAN             Reviewed;         671 AA.
AC   Q13546; A0AV89; B2RAG1; B4E3F9; Q13180; Q59H33;
DE   RecName: Full=Receptor-interacting serine/threonine-protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Cell death protein RIP;
DE   AltName: Full=Receptor-interacting protein 1;
DE            Short=RIP-1;
DE   AltName: Full=Serine/threonine-protein kinase RIP;
GN   Name=RIPK1; Synonyms=RIP, RIP1;
DR   GuidetoPHARMACOLOGY; 2189; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0070513; F:death domain binding; IPI:BHF-UCL.
DR   GO; GO:0005123; F:death receptor binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0007257; P:activation of JUN kinase activity; TAS:BHF-UCL.
DR   GO; GO:1990000; P:amyloid fibril formation; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0044257; P:cellular protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070266; P:necroptotic process; IMP:UniProtKB.
DR   GO; GO:0097527; P:necroptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0036289; P:peptidyl-serine autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0045651; P:positive regulation of macrophage differentiation; IMP:UniProtKB.
DR   GO; GO:0060545; P:positive regulation of necroptotic process; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; TAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051291; P:protein heterooligomerization; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0070926; P:regulation of ATP:ADP antiporter activity; IMP:BHF-UCL.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0097343; P:ripoptosome assembly; IMP:UniProtKB.
DR   GO; GO:0070231; P:T cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IC:BHF-UCL.
//
ID   RIPK3_HUMAN             Reviewed;         518 AA.
AC   Q9Y572; B4DJL9; C4AM87; Q5J795; Q5J796; Q6P5Y1;
DE   RecName: Full=Receptor-interacting serine/threonine-protein kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=RIP-like protein kinase 3;
DE   AltName: Full=Receptor-interacting protein 3;
DE            Short=RIP-3;
GN   Name=RIPK3; Synonyms=RIP3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004704; F:NF-kappaB-inducing kinase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IMP:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0032147; P:activation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:1990000; P:amyloid fibril formation; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048535; P:lymph node development; ISS:UniProtKB.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070266; P:necroptotic process; IMP:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0060545; P:positive regulation of necroptotic process; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010922; P:positive regulation of phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0046006; P:regulation of activated T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0070235; P:regulation of activation-induced cell death of T cells; ISS:UniProtKB.
DR   GO; GO:0002819; P:regulation of adaptive immune response; ISS:UniProtKB.
DR   GO; GO:2000452; P:regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation; ISS:UniProtKB.
DR   GO; GO:0032649; P:regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0001914; P:regulation of T cell mediated cytotoxicity; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048536; P:spleen development; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0048538; P:thymus development; ISS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   RIPK2_HUMAN             Reviewed;         540 AA.
AC   O43353; B7Z748; Q6UWF0;
DE   RecName: Full=Receptor-interacting serine/threonine-protein kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=CARD-containing interleukin-1 beta-converting enzyme-associated kinase;
DE            Short=CARD-containing IL-1 beta ICE-kinase;
DE   AltName: Full=RIP-like-interacting CLARP kinase;
DE   AltName: Full=Receptor-interacting protein 2;
DE            Short=RIP-2;
DE   AltName: Full=Tyrosine-protein kinase RIPK2;
DE            EC=2.7.10.2;
GN   Name=RIPK2; Synonyms=CARDIAK, RICK, RIP2;
GN   ORFNames=UNQ277/PRO314/PRO34092;
DR   GuidetoPHARMACOLOGY; 2190; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050700; F:CARD domain binding; IPI:UniProtKB.
DR   GO; GO:0030274; F:LIM domain binding; IPI:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0002250; P:adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; IEA:Ensembl.
DR   GO; GO:0071225; P:cellular response to muramyl dipeptide; IDA:UniProtKB.
DR   GO; GO:0071224; P:cellular response to peptidoglycan; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070427; P:nucleotide-binding oligomerization domain containing 1 signaling pathway; IEA:Ensembl.
DR   GO; GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IEA:Ensembl.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:MGI.
DR   GO; GO:0033091; P:positive regulation of immature T cell proliferation; IEA:Ensembl.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; NAS:BHF-UCL.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; NAS:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; NAS:BHF-UCL.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0045627; P:positive regulation of T-helper 1 cell differentiation; IEA:Ensembl.
DR   GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0070671; P:response to interleukin-12; IEA:Ensembl.
DR   GO; GO:0070673; P:response to interleukin-18; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; IDA:MGI.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   RIPK4_HUMAN             Reviewed;         832 AA.
AC   P57078; Q96KH0;
DE   RecName: Full=Receptor-interacting serine/threonine-protein kinase 4;
DE            EC=2.7.11.1;
DE   AltName: Full=Ankyrin repeat domain-containing protein 3;
DE   AltName: Full=PKC-delta-interacting protein kinase;
GN   Name=RIPK4; Synonyms=ANKRD3, DIK;
DR   GuidetoPHARMACOLOGY; 2192; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
//
ID   RIPL1_HUMAN             Reviewed;         403 AA.
AC   Q5EBL4; Q66K36; Q8N1M0;
DE   RecName: Full=RILP-like protein 1;
DE   AltName: Full=Rab-interacting lysosomal-like protein 1;
GN   Name=RILPL1; Synonyms=RLP1;
DR   GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:1901214; P:regulation of neuron death; ISS:UniProtKB.
//
ID   RIPL2_HUMAN             Reviewed;         211 AA.
AC   Q969X0;
DE   RecName: Full=RILP-like protein 2;
DE   AltName: Full=Rab-interacting lysosomal protein-like 2;
DE   AltName: Full=p40phox-binding protein;
GN   Name=RILPL2; Synonyms=RLP2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
//
ID   RIPP1_HUMAN             Reviewed;         151 AA.
AC   Q0D2K3; A0JP63; Q0VGB3; Q5JRB8; Q5JRB9;
DE   RecName: Full=Protein ripply1;
GN   Name=RIPPLY1;
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; ISS:UniProtKB.
DR   GO; GO:0001757; P:somite specification; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RIPP2_HUMAN             Reviewed;         128 AA.
AC   Q5TAB7; Q5TAB6;
DE   RecName: Full=Protein ripply2;
GN   Name=RIPPLY2; Synonyms=C6orf159;
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; ISS:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; ISS:UniProtKB.
//
ID   RIP_HUMAN               Reviewed;         219 AA.
AC   Q86UA6; B4DI36; B4DTX7; E9PES3; J3KNH8; Q4G2Y0; Q4G2Y5; Q4G2Y8;
AC   Q6B4V9; Q6B4W0; Q6B4W1; Q6B4W4; Q86X49; Q9BT00;
DE   RecName: Full=RPA-interacting protein;
DE            Short=hRIP;
GN   Name=RPAIN; Synonyms=RIP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032403; F:protein complex binding; IPI:MGI.
DR   GO; GO:0006310; P:DNA recombination; IPI:MGI.
DR   GO; GO:0006281; P:DNA repair; IPI:MGI.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IPI:MGI.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:MGI.
DR   GO; GO:0009411; P:response to UV; IDA:MGI.
//
ID   RIR1_HUMAN              Reviewed;         792 AA.
AC   P23921; Q9UNN2;
DE   RecName: Full=Ribonucleoside-diphosphate reductase large subunit;
DE            EC=1.17.4.1;
DE   AltName: Full=Ribonucleoside-diphosphate reductase subunit M1;
DE   AltName: Full=Ribonucleotide reductase large subunit;
GN   Name=RRM1; Synonyms=RR1;
DR   GuidetoPHARMACOLOGY; 2630; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RIR2B_HUMAN             Reviewed;         351 AA.
AC   Q7LG56; B4E2N4; Q17R22; Q75PQ6; Q75PQ7; Q75PY8; Q75PY9; Q86YE3;
AC   Q9NPD6; Q9NTD8; Q9NUW3;
DE   RecName: Full=Ribonucleoside-diphosphate reductase subunit M2 B;
DE            EC=1.17.4.1;
DE   AltName: Full=TP53-inducible ribonucleotide reductase M2 B;
DE   AltName: Full=p53-inducible ribonucleotide reductase small subunit 2-like protein;
DE            Short=p53R2;
GN   Name=RRM2B; Synonyms=P53R2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:UniProtKB-EC.
DR   GO; GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0009200; P:deoxyribonucleoside triphosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IEA:Ensembl.
DR   GO; GO:1902254; P:negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0003014; P:renal system process; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RIR2_HUMAN              Reviewed;         389 AA.
AC   P31350; B2R9B5; J3KP43; Q5WRU7;
DE   RecName: Full=Ribonucleoside-diphosphate reductase subunit M2;
DE            EC=1.17.4.1;
DE   AltName: Full=Ribonucleotide reductase small chain;
DE   AltName: Full=Ribonucleotide reductase small subunit;
GN   Name=RRM2; Synonyms=RR2;
DR   GuidetoPHARMACOLOGY; 2631; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
DR   GO; GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniPathway.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051290; P:protein heterotetramerization; IEA:Ensembl.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RISC_HUMAN              Reviewed;         452 AA.
AC   Q9HB40; Q96A94; Q9H3F0;
DE   RecName: Full=Retinoid-inducible serine carboxypeptidase;
DE            EC=3.4.16.-;
DE   AltName: Full=Serine carboxypeptidase 1;
DE   Flags: Precursor;
GN   Name=SCPEP1; Synonyms=RISC, SCP1; ORFNames=MSTP034, UNQ265/PRO302;
DR   GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IEA:Ensembl.
//
ID   RIT1_HUMAN              Reviewed;         219 AA.
AC   Q92963; B4DQE8; O00646; O00720; Q5VY89; Q5VY90;
DE   RecName: Full=GTP-binding protein Rit1;
DE   AltName: Full=Ras-like protein expressed in many tissues;
DE   AltName: Full=Ras-like without CAAX protein 1;
GN   Name=RIT1; Synonyms=RIBB, RIT, ROC1;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   RITA1_HUMAN             Reviewed;         269 AA.
AC   Q96K30; B3KVZ4; C9JIN1; Q53GM3; Q96K25;
DE   RecName: Full=RBPJ-interacting and tubulin-associated protein 1;
DE   AltName: Full=RBPJ-interacting and tubulin-associated protein;
GN   Name=RITA1; Synonyms=C12orf52, RITA; ORFNames=PSEC0043;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0051168; P:nuclear export; IDA:UniProtKB.
//
ID   RIT2_HUMAN              Reviewed;         217 AA.
AC   Q99578; B2R9L1; O15295; Q8TD69; Q8WVF6; Q92964;
DE   RecName: Full=GTP-binding protein Rit2;
DE   AltName: Full=Ras-like protein expressed in neurons;
DE   AltName: Full=Ras-like without CAAX protein 2;
GN   Name=RIT2; Synonyms=RIN, ROC2;
DR   GO; GO:0005516; F:calmodulin binding; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   RK_HUMAN                Reviewed;         563 AA.
AC   Q15835; Q53X14;
DE   RecName: Full=Rhodopsin kinase;
DE            Short=RK;
DE            EC=2.7.11.14;
DE   AltName: Full=G protein-coupled receptor kinase 1;
DE   Flags: Precursor;
GN   Name=GRK1; Synonyms=RHOK;
DR   GuidetoPHARMACOLOGY; 1465; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0050254; F:rhodopsin kinase activity; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008594; P:photoreceptor cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IEA:Ensembl.
DR   GO; GO:0060060; P:post-embryonic retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
DR   GO; GO:0022400; P:regulation of rhodopsin mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016056; P:rhodopsin mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RL10A_HUMAN             Reviewed;         217 AA.
AC   P62906; B2R801; P52859; P53025; Q5TZT6; Q8J013;
DE   RecName: Full=60S ribosomal protein L10a;
DE   AltName: Full=CSA-19;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 6;
DE            Short=NEDD-6;
GN   Name=RPL10A; Synonyms=NEDD6;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL10L_HUMAN             Reviewed;         214 AA.
AC   Q96L21; Q8IUD1;
DE   RecName: Full=60S ribosomal protein L10-like;
GN   Name=RPL10L;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RL10_HUMAN              Reviewed;         214 AA.
AC   P27635; A3KQT0; D3DWW6; Q16470; Q2HXT7; Q53FH7; Q6FGN8; Q8TDA5;
DE   RecName: Full=60S ribosomal protein L10;
DE   AltName: Full=Laminin receptor homolog;
DE   AltName: Full=Protein QM;
DE   AltName: Full=Tumor suppressor QM;
GN   Name=RPL10; Synonyms=DXS648E, QM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL11_HUMAN              Reviewed;         178 AA.
AC   P62913; P25121; P39026; Q8TDH2; Q9Y674;
DE   RecName: Full=60S ribosomal protein L11;
DE   AltName: Full=CLL-associated antigen KW-12;
GN   Name=RPL11;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0034504; P:protein localization to nucleus; ISS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; IMP:UniProtKB.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL12_HUMAN              Reviewed;         165 AA.
AC   P30050; Q5VVV2; Q6PB27;
DE   RecName: Full=60S ribosomal protein L12;
GN   Name=RPL12;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL13A_HUMAN             Reviewed;         203 AA.
AC   P40429; A8K505;
DE   RecName: Full=60S ribosomal protein L13a;
DE   AltName: Full=23 kDa highly basic protein;
GN   Name=RPL13A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:1901194; P:negative regulation of formation of translation preinitiation complex; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL13_HUMAN              Reviewed;         211 AA.
AC   P26373; B4DLX3; F5H1S2; Q3KQT8; Q567Q8; Q9BPX0;
DE   RecName: Full=60S ribosomal protein L13;
DE   AltName: Full=Breast basic conserved protein 1;
GN   Name=RPL13; Synonyms=BBC1; ORFNames=OK/SW-cl.46;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL14_HUMAN              Reviewed;         215 AA.
AC   P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8;
AC   Q9BW65; Q9BYF6;
DE   RecName: Full=60S ribosomal protein L14;
DE   AltName: Full=CAG-ISL 7;
GN   Name=RPL14;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL15_HUMAN              Reviewed;         204 AA.
AC   P61313; P39030; P41051; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44;
AC   Q9H2E5;
DE   RecName: Full=60S ribosomal protein L15;
GN   Name=RPL15; Synonyms=EC45; ORFNames=TCBAP0781;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL17_HUMAN              Reviewed;         184 AA.
AC   P18621; B2R4H3; B4E3C2; B5ME31; J3QL51; Q3KQW2; Q6NZ54; Q7M4M5;
DE   RecName: Full=60S ribosomal protein L17;
DE   AltName: Full=60S ribosomal protein L23;
DE   AltName: Full=PD-1;
GN   Name=RPL17;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL18A_HUMAN             Reviewed;         176 AA.
AC   Q02543;
DE   RecName: Full=60S ribosomal protein L18a;
GN   Name=RPL18A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL18_HUMAN              Reviewed;         188 AA.
AC   Q07020; Q8WTZ6;
DE   RecName: Full=60S ribosomal protein L18;
GN   Name=RPL18;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL19_HUMAN              Reviewed;         196 AA.
AC   P84098; B2R4K2; P14118; P22908; Q502Y6; Q7Z6E4;
DE   RecName: Full=60S ribosomal protein L19;
GN   Name=RPL19;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL1D1_HUMAN             Reviewed;         490 AA.
AC   O76021; D3DUG7; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9;
DE   RecName: Full=Ribosomal L1 domain-containing protein 1;
DE   AltName: Full=CATX-11;
DE   AltName: Full=Cellular senescence-inhibited gene protein;
DE   AltName: Full=Protein PBK1;
GN   Name=RSL1D1; Synonyms=CATX11, CSIG, PBK1; ORFNames=L12;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IMP:MGI.
//
ID   RL21_HUMAN              Reviewed;         160 AA.
AC   P46778; Q16699;
DE   RecName: Full=60S ribosomal protein L21;
GN   Name=RPL21;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL22L_HUMAN             Reviewed;         122 AA.
AC   Q6P5R6; Q32Q77;
DE   RecName: Full=60S ribosomal protein L22-like 1;
GN   Name=RPL22L1;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RL22_HUMAN              Reviewed;         128 AA.
AC   P35268; B2R495; Q6IBD1;
DE   RecName: Full=60S ribosomal protein L22;
DE   AltName: Full=EBER-associated protein;
DE            Short=EAP;
DE   AltName: Full=Epstein-Barr virus small RNA-associated protein;
DE   AltName: Full=Heparin-binding protein HBp15;
GN   Name=RPL22;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0046632; P:alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL23A_HUMAN             Reviewed;         156 AA.
AC   P62750; B2R5B2; P29316; P39024; Q92774;
DE   RecName: Full=60S ribosomal protein L23a;
GN   Name=RPL23A;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL23_HUMAN              Reviewed;         140 AA.
AC   P62829; P23131; P24048; Q29246; Q3SWV7; Q6P5S1;
DE   RecName: Full=60S ribosomal protein L23;
DE   AltName: Full=60S ribosomal protein L17;
GN   Name=RPL23;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006610; P:ribosomal protein import into nucleus; NAS:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL24_HUMAN              Reviewed;         157 AA.
AC   P83731; B2R4Y3; P38663; Q6IBS3;
DE   RecName: Full=60S ribosomal protein L24;
DE   AltName: Full=60S ribosomal protein L30;
GN   Name=RPL24;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL26L_HUMAN             Reviewed;         145 AA.
AC   Q9UNX3; B3KY82; D3DQM0;
DE   RecName: Full=60S ribosomal protein L26-like 1;
GN   Name=RPL26L1; Synonyms=RPL26P1;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL26_HUMAN              Reviewed;         145 AA.
AC   P61254; B2R4F0; D3DTR8; Q02877; Q6IPY2;
DE   RecName: Full=60S ribosomal protein L26;
GN   Name=RPL26;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL27A_HUMAN             Reviewed;         148 AA.
AC   P46776; B2R4B3;
DE   RecName: Full=60S ribosomal protein L27a;
GN   Name=RPL27A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL27_HUMAN              Reviewed;         136 AA.
AC   P61353; P08526; Q4G0A9;
DE   RecName: Full=60S ribosomal protein L27;
GN   Name=RPL27;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL28_HUMAN              Reviewed;         137 AA.
AC   P46779; B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; Q6IAY0; Q96FX1;
AC   Q9BWQ0;
DE   RecName: Full=60S ribosomal protein L28;
GN   Name=RPL28;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL29_HUMAN              Reviewed;         159 AA.
AC   P47914; A8K0H3; B2R4M8; Q6IPY3;
DE   RecName: Full=60S ribosomal protein L29;
DE   AltName: Full=Cell surface heparin-binding protein HIP;
GN   Name=RPL29;
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007566; P:embryo implantation; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL30_HUMAN              Reviewed;         115 AA.
AC   P62888; B2R591; P04645; Q502Z6;
DE   RecName: Full=60S ribosomal protein L30;
GN   Name=RPL30;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL31_HUMAN              Reviewed;         125 AA.
AC   P62899; B7Z4K2; D3DVJ4; P12947; Q53SQ5; Q6IRZ0; Q6LBJ6;
DE   RecName: Full=60S ribosomal protein L31;
GN   Name=RPL31;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL32_HUMAN              Reviewed;         135 AA.
AC   P62910; B2R4Q3; P02433;
DE   RecName: Full=60S ribosomal protein L32;
GN   Name=RPL32; ORFNames=PP9932;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL34_HUMAN              Reviewed;         117 AA.
AC   P49207; Q6FG66; Q9BUZ2;
DE   RecName: Full=60S ribosomal protein L34;
GN   Name=RPL34;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL35A_HUMAN             Reviewed;         110 AA.
AC   P18077; Q08ES9; Q9BVN7;
DE   RecName: Full=60S ribosomal protein L35a;
DE   AltName: Full=Cell growth-inhibiting gene 33 protein;
GN   Name=RPL35A; ORFNames=GIG33;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL35_HUMAN              Reviewed;         123 AA.
AC   P42766; A8K4V7; Q4VBY5; Q5JTN5; Q6IBC7; Q96QJ7; Q9BYF4;
DE   RecName: Full=60S ribosomal protein L35;
GN   Name=RPL35;
DR   GO; GO:0003729; F:mRNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL36A_HUMAN             Reviewed;         106 AA.
AC   P83881; P09896; P10661; Q08ES5; Q5J9I6;
DE   RecName: Full=60S ribosomal protein L36a;
DE   AltName: Full=60S ribosomal protein L44;
DE   AltName: Full=Cell growth-inhibiting gene 15 protein;
DE   AltName: Full=Cell migration-inducing gene 6 protein;
GN   Name=RPL36A; Synonyms=RPL44; ORFNames=GIG15, MIG6;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL36L_HUMAN             Reviewed;         106 AA.
AC   Q969Q0; Q3B7A5;
DE   RecName: Full=60S ribosomal protein L36a-like;
GN   Name=RPL36AL;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RL36_HUMAN              Reviewed;         105 AA.
AC   Q9Y3U8; B2R4Y1; D6W634; Q6FIG1; Q9UQF6;
DE   RecName: Full=60S ribosomal protein L36;
GN   Name=RPL36;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL37A_HUMAN             Reviewed;          92 AA.
AC   P61513; P12751; Q6FGF5;
DE   RecName: Full=60S ribosomal protein L37a;
GN   Name=RPL37A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL37L_HUMAN             Reviewed;          93 AA.
AC   A6NKH3;
DE   RecName: Full=Putative 60S ribosomal protein L37a-like;
GN   Name=RPL37L;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RL37_HUMAN              Reviewed;          97 AA.
AC   P61927; B2R4H2; P02403; Q6IBB4; Q99883;
DE   RecName: Full=60S ribosomal protein L37;
DE   AltName: Full=G1.16;
GN   Name=RPL37;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL38_HUMAN              Reviewed;          70 AA.
AC   P63173; B2R5A8; P23411;
DE   RecName: Full=60S ribosomal protein L38;
GN   Name=RPL38;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0034463; P:90S preribosome assembly; IEA:Ensembl.
DR   GO; GO:0048318; P:axial mesoderm development; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL39L_HUMAN             Reviewed;          51 AA.
AC   Q96EH5; Q8IUD0;
DE   RecName: Full=60S ribosomal protein L39-like;
DE   AltName: Full=60S ribosomal protein L39-2;
GN   Name=RPL39L; Synonyms=RPL39L1;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RL39_HUMAN              Reviewed;          51 AA.
AC   P62891; P02404; P39025; Q9BYF2;
DE   RecName: Full=60S ribosomal protein L39;
GN   Name=RPL39;
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL3L_HUMAN              Reviewed;         407 AA.
AC   Q92901;
DE   RecName: Full=60S ribosomal protein L3-like;
GN   Name=RPL3L;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL3R1_HUMAN             Reviewed;         469 AA.
AC   Q9NSD7; Q14DA5;
DE   RecName: Full=Relaxin-3 receptor 1;
DE            Short=RLN3 receptor 1;
DE   AltName: Full=G protein-coupled receptor SALPR;
DE   AltName: Full=G-protein coupled receptor GPCR135;
DE   AltName: Full=Relaxin family peptide receptor 3;
DE   AltName: Full=Somatostatin- and angiotensin-like peptide receptor;
GN   Name=RXFP3; Synonyms=RLN3R1, SALPR;
DR   GuidetoPHARMACOLOGY; 353; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004982; F:N-formyl peptide receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
//
ID   RL3R2_HUMAN             Reviewed;         374 AA.
AC   Q8TDU9; B0M0L4; Q3MJB1; Q8NGZ8;
DE   RecName: Full=Relaxin-3 receptor 2;
DE            Short=RLN3 receptor 2;
DE   AltName: Full=G-protein coupled receptor 100;
DE   AltName: Full=G-protein coupled receptor GPCR142;
DE   AltName: Full=Insulin-like peptide INSL5 receptor;
DE   AltName: Full=Relaxin family peptide receptor 4;
GN   Name=RXFP4; Synonyms=GPR100, RLN3R2;
DR   GuidetoPHARMACOLOGY; 354; -.
DR   GO; GO:0004945; F:angiotensin type II receptor activity; IEA:InterPro.
//
ID   RL3_HUMAN               Reviewed;         403 AA.
AC   P39023; B2RDV9; Q15548; Q5I0G0;
DE   RecName: Full=60S ribosomal protein L3;
DE   AltName: Full=HIV-1 TAR RNA-binding protein B;
DE            Short=TARBP-B;
GN   Name=RPL3; ORFNames=OK/SW-cl.32;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL40_HUMAN              Reviewed;         128 AA.
AC   P62987; P02248; P02249; P02250; P14793; P62988; Q29120; Q6LBL4;
AC   Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1;
AC   Q9UEK8; Q9UPK7;
DE   RecName: Full=Ubiquitin-60S ribosomal protein L40;
DE   AltName: Full=CEP52;
DE   AltName: Full=Ubiquitin A-52 residue ribosomal protein fusion product 1;
DE   Contains:
DE     RecName: Full=Ubiquitin;
DE   Contains:
DE     RecName: Full=60S ribosomal protein L40;
DE   Flags: Precursor;
GN   Name=UBA52; Synonyms=UBCEP2;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   RL41_HUMAN              Reviewed;          25 AA.
AC   P62945; A6NG21; P28751;
DE   RecName: Full=60S ribosomal protein L41;
DE   AltName: Full=HG12;
GN   Name=RPL41;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL4_HUMAN               Reviewed;         427 AA.
AC   P36578; A8K502; P39029; Q4VBR0; Q969Z9;
DE   RecName: Full=60S ribosomal protein L4;
DE   AltName: Full=60S ribosomal protein L1;
GN   Name=RPL4; Synonyms=RPL1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL5_HUMAN               Reviewed;         297 AA.
AC   P46777; Q32LZ3; Q53HH6; Q9H3F4;
DE   RecName: Full=60S ribosomal protein L5;
GN   Name=RPL5; ORFNames=MSTP030;
DR   GO; GO:0008097; F:5S rRNA binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL6_HUMAN               Reviewed;         288 AA.
AC   Q02878; Q2M3Q3; Q8WW97;
DE   RecName: Full=60S ribosomal protein L6;
DE   AltName: Full=Neoplasm-related protein C140;
DE   AltName: Full=Tax-responsive enhancer element-binding protein 107;
DE            Short=TaxREB107;
GN   Name=RPL6; Synonyms=TXREB1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL7A_HUMAN              Reviewed;         266 AA.
AC   P62424; P11518; Q5T8U4;
DE   RecName: Full=60S ribosomal protein L7a;
DE   AltName: Full=PLA-X polypeptide;
DE   AltName: Full=Surfeit locus protein 3;
GN   Name=RPL7A; Synonyms=SURF-3, SURF3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL7L_HUMAN              Reviewed;         246 AA.
AC   Q6DKI1; A8K7D4; Q5TFZ5; Q6PEK3;
DE   RecName: Full=60S ribosomal protein L7-like 1;
GN   Name=RPL7L1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RL7_HUMAN               Reviewed;         248 AA.
AC   P18124; A8K504; Q15289; Q3KQU0; Q5I0X1; Q6IBM9;
DE   RecName: Full=60S ribosomal protein L7;
GN   Name=RPL7;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0003729; F:mRNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:MGI.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL8_HUMAN               Reviewed;         257 AA.
AC   P62917; A8K094; D3DWN2; P25120; Q567Q7; Q969V7; Q9BWQ9;
DE   RecName: Full=60S ribosomal protein L8;
GN   Name=RPL8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RL9_HUMAN               Reviewed;         192 AA.
AC   P32969;
DE   RecName: Full=60S ribosomal protein L9;
GN   Name=RPL9; ORFNames=OK/SW-cl.103;
GN   and
GN   Name=RPL9P7;
GN   and
GN   Name=RPL9P8;
GN   and
GN   Name=RPL9P9;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RLA0L_HUMAN             Reviewed;         317 AA.
AC   Q8NHW5;
DE   RecName: Full=60S acidic ribosomal protein P0-like;
GN   Name=RPLP0P6;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   GO; GO:0006414; P:translational elongation; IEA:InterPro.
//
ID   RLA0_HUMAN              Reviewed;         317 AA.
AC   P05388; Q9BVK4;
DE   RecName: Full=60S acidic ribosomal protein P0;
DE   AltName: Full=60S ribosomal protein L10E;
GN   Name=RPLP0;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RLA1_HUMAN              Reviewed;         114 AA.
AC   P05386; A6NIB2;
DE   RecName: Full=60S acidic ribosomal protein P1;
GN   Name=RPLP1; Synonyms=RRP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RLA2_HUMAN              Reviewed;         115 AA.
AC   P05387; Q6FG96;
DE   RecName: Full=60S acidic ribosomal protein P2;
DE   AltName: Full=Renal carcinoma antigen NY-REN-44;
GN   Name=RPLP2; Synonyms=D11S2243E, RPP2;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RLBP1_HUMAN             Reviewed;         317 AA.
AC   P12271; B2R667;
DE   RecName: Full=Retinaldehyde-binding protein 1;
DE   AltName: Full=Cellular retinaldehyde-binding protein;
GN   Name=RLBP1; Synonyms=CRALBP;
DR   GO; GO:0005502; F:11-cis retinal binding; IEA:Ensembl.
DR   GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
DR   GO; GO:0006776; P:vitamin A metabolic process; TAS:ProtInc.
//
ID   RLF_HUMAN               Reviewed;        1914 AA.
AC   Q13129; Q14CQ1; Q9NU60;
DE   RecName: Full=Zinc finger protein Rlf;
DE   AltName: Full=Rearranged L-myc fusion gene protein;
DE   AltName: Full=Zn-15-related protein;
GN   Name=RLF;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0051276; P:chromosome organization; IDA:UniProtKB.
DR   GO; GO:0015074; P:DNA integration; IDA:UniProtKB.
DR   GO; GO:0009294; P:DNA mediated transformation; NAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RLGPB_HUMAN             Reviewed;        1494 AA.
AC   Q86X10; A2A2E8; Q5TG31; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1;
AC   Q9Y3G9;
DE   RecName: Full=Ral GTPase-activating protein subunit beta;
DE   AltName: Full=p170;
GN   Name=RALGAPB; Synonyms=KIAA1219;
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0017123; F:Ral GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0032859; P:activation of Ral GTPase activity; ISS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0032484; P:Ral protein signal transduction; IEA:Ensembl.
DR   GO; GO:0060178; P:regulation of exocyst localization; IEA:Ensembl.
//
ID   RLP24_HUMAN             Reviewed;         163 AA.
AC   Q9UHA3; B2RD72; Q561V8; Q8N6S8; Q96B04; Q96C76; Q96HJ1;
DE   RecName: Full=Probable ribosome biogenesis protein RLP24;
DE   AltName: Full=Ribosomal L24 domain-containing protein 1;
DE   AltName: Full=Ribosomal protein L24-like;
GN   Name=RSL24D1; Synonyms=C15orf15, RPL24L; ORFNames=My024;
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   RM01_HUMAN              Reviewed;         325 AA.
AC   Q9BYD6; A6NG03; Q4W5B8; Q6IAG4; Q96BW3; Q9H793; Q9NRL5;
DE   RecName: Full=39S ribosomal protein L1, mitochondrial;
DE            Short=L1mt;
DE            Short=MRP-L1;
DE   Flags: Precursor;
GN   Name=MRPL1; ORFNames=BM-022;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM02_HUMAN              Reviewed;         305 AA.
AC   Q5T653; B2RC56; Q8WUL1; Q96Q56; Q9Y311;
DE   RecName: Full=39S ribosomal protein L2, mitochondrial;
DE            Short=L2mt;
DE            Short=MRP-L2;
DE   Flags: Precursor;
GN   Name=MRPL2; ORFNames=CGI-22;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM03_HUMAN              Reviewed;         348 AA.
AC   P09001; Q6IBT2;
DE   RecName: Full=39S ribosomal protein L3, mitochondrial;
DE            Short=L3mt;
DE            Short=MRP-L3;
GN   Name=MRPL3; Synonyms=MRL3, RPML3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   RM04_HUMAN              Reviewed;         311 AA.
AC   Q9BYD3; A6NNV7; Q9BW07; Q9H4N2; Q9Y317;
DE   RecName: Full=39S ribosomal protein L4, mitochondrial;
DE            Short=L4mt;
DE            Short=MRP-L4;
GN   Name=MRPL4; ORFNames=CDABP0091, CGI-28;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM09_HUMAN              Reviewed;         267 AA.
AC   Q9BYD2; B2RD99; Q5SZR2; Q9BSW8;
DE   RecName: Full=39S ribosomal protein L9, mitochondrial;
DE            Short=L9mt;
DE            Short=MRP-L9;
DE   Flags: Precursor;
GN   Name=MRPL9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM10_HUMAN              Reviewed;         261 AA.
AC   Q7Z7H8; A6NGJ4; Q96B80; Q96Q55;
DE   RecName: Full=39S ribosomal protein L10, mitochondrial;
DE            Short=L10mt;
DE            Short=MRP-L10;
DE   AltName: Full=39S ribosomal protein L8, mitochondrial;
DE            Short=L8mt;
DE            Short=MRP-L8;
DE   Flags: Precursor;
GN   Name=MRPL10; Synonyms=MRPL8, RPML8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
//
ID   RM12_HUMAN              Reviewed;         198 AA.
AC   P52815; Q969U0; Q9HCA2; Q9UQJ3;
DE   RecName: Full=39S ribosomal protein L12, mitochondrial;
DE            Short=L12mt;
DE            Short=MRP-L12;
DE   AltName: Full=5c5-2;
DE   Flags: Precursor;
GN   Name=MRPL12; Synonyms=RPML12;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IDA:HGNC.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM11_HUMAN              Reviewed;         192 AA.
AC   Q9Y3B7; A6NLT0; A8K219; Q32P46; Q96Q73;
DE   RecName: Full=39S ribosomal protein L11, mitochondrial;
DE            Short=L11mt;
DE            Short=MRP-L11;
DE   Flags: Precursor;
GN   Name=MRPL11; ORFNames=CGI-113;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM13_HUMAN              Reviewed;         178 AA.
AC   Q9BYD1; B2R4R8; Q9UI04;
DE   RecName: Full=39S ribosomal protein L13, mitochondrial;
DE            Short=L13mt;
DE            Short=MRP-L13;
GN   Name=MRPL13;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM14_HUMAN              Reviewed;         145 AA.
AC   Q6P1L8; B2R575; Q96Q72;
DE   RecName: Full=39S ribosomal protein L14, mitochondrial;
DE            Short=L14mt;
DE            Short=MRP-L14;
DE   AltName: Full=39S ribosomal protein L32, mitochondrial;
DE            Short=L32mt;
DE            Short=MRP-L32;
DE   Flags: Precursor;
GN   Name=MRPL14; Synonyms=MRPL32, RPML32;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM15_HUMAN              Reviewed;         296 AA.
AC   Q9P015; Q96Q54; Q9H0Y1;
DE   RecName: Full=39S ribosomal protein L15, mitochondrial;
DE            Short=L15mt;
DE            Short=MRP-L15;
DE   Flags: Precursor;
GN   Name=MRPL15; ORFNames=HSPC145;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM16_HUMAN              Reviewed;         251 AA.
AC   Q9NX20; Q9BYD0; Q9HB70;
DE   RecName: Full=39S ribosomal protein L16, mitochondrial;
DE            Short=L16mt;
DE            Short=MRP-L16;
DE   Flags: Precursor;
GN   Name=MRPL16; ORFNames=PNAS-111;
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM17_HUMAN              Reviewed;         175 AA.
AC   Q9NRX2; D3DQU3; Q6IAH8; Q96Q53; Q9C066;
DE   RecName: Full=39S ribosomal protein L17, mitochondrial;
DE            Short=L17mt;
DE            Short=MRP-L17;
DE   AltName: Full=LYST-interacting protein 2;
DE   Flags: Precursor;
GN   Name=MRPL17; Synonyms=LIP2;
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM18_HUMAN              Reviewed;         180 AA.
AC   Q9H0U6; Q5TAP9; Q9NZW8;
DE   RecName: Full=39S ribosomal protein L18, mitochondrial;
DE            Short=L18mt;
DE            Short=MRP-L18;
DE   Flags: Precursor;
GN   Name=MRPL18; ORFNames=HSPC071;
DR   GO; GO:0008097; F:5S rRNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0035928; P:rRNA import into mitochondrion; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM19_HUMAN              Reviewed;         292 AA.
AC   P49406; Q53TX9; Q96Q52;
DE   RecName: Full=39S ribosomal protein L19, mitochondrial;
DE            Short=L19mt;
DE            Short=MRP-L19;
DE   AltName: Full=39S ribosomal protein L15, mitochondrial;
DE            Short=L15mt;
DE            Short=MRP-L15;
DE   Flags: Precursor;
GN   Name=MRPL19; Synonyms=KIAA0104, MRPL15;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM20_HUMAN              Reviewed;         149 AA.
AC   Q9BYC9; B2RE41;
DE   RecName: Full=39S ribosomal protein L20, mitochondrial;
DE            Short=L20mt;
DE            Short=MRP-L20;
DE   Flags: Precursor;
GN   Name=MRPL20;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM21_HUMAN              Reviewed;         205 AA.
AC   Q7Z2W9; A6NKU0; C9JPR2;
DE   RecName: Full=39S ribosomal protein L21, mitochondrial;
DE            Short=L21mt;
DE            Short=MRP-L21;
DE   Flags: Precursor;
GN   Name=MRPL21;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM22_HUMAN              Reviewed;         206 AA.
AC   Q9NWU5; A6NGJ8; Q5H9Q1; Q96Q51; Q9P006;
DE   RecName: Full=39S ribosomal protein L22, mitochondrial;
DE            Short=L22mt;
DE            Short=MRP-L22;
DE   AltName: Full=39S ribosomal protein L25, mitochondrial;
DE            Short=L25mt;
DE            Short=MRP-L25;
DE   Flags: Precursor;
GN   Name=MRPL22; Synonyms=MRPL25, RPML25; ORFNames=HSPC158;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM23_HUMAN              Reviewed;         153 AA.
AC   Q16540; A8MT29; Q96Q71;
DE   RecName: Full=39S ribosomal protein L23, mitochondrial;
DE            Short=L23mt;
DE            Short=MRP-L23;
DE   AltName: Full=L23 mitochondrial-related protein;
DE   AltName: Full=Ribosomal protein L23-like;
GN   Name=MRPL23; Synonyms=L23MRP, RPL23L;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   RM24_HUMAN              Reviewed;         216 AA.
AC   Q96A35; D3DVC8; Q53G65; Q53HT0; Q5SYZ9; Q5SZ00; Q5SZ02; Q96Q70;
AC   Q9H7G3;
DE   RecName: Full=39S ribosomal protein L24, mitochondrial;
DE            Short=L24mt;
DE            Short=MRP-L24;
DE   Flags: Precursor;
GN   Name=MRPL24;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM27_HUMAN              Reviewed;         148 AA.
AC   Q9P0M9; B2RE14;
DE   RecName: Full=39S ribosomal protein L27, mitochondrial;
DE            Short=L27mt;
DE            Short=MRP-L27;
GN   Name=MRPL27; ORFNames=HSPC250;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM28_HUMAN              Reviewed;         256 AA.
AC   Q13084; B2RCM4; D3DU46; Q4TT39; Q96S26; Q9BQD8; Q9BR04;
DE   RecName: Full=39S ribosomal protein L28, mitochondrial;
DE            Short=L28mt;
DE            Short=MRP-L28;
DE   AltName: Full=Melanoma antigen p15;
DE   AltName: Full=Melanoma-associated antigen recognized by T-lymphocytes;
DE   Flags: Precursor;
GN   Name=MRPL28; Synonyms=MAAT1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM32_HUMAN              Reviewed;         188 AA.
AC   Q9BYC8; Q96Q68; Q9P098;
DE   RecName: Full=39S ribosomal protein L32, mitochondrial;
DE            Short=L32mt;
DE            Short=MRP-L32;
DE   Flags: Precursor;
GN   Name=MRPL32; ORFNames=HSPC283;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM33_HUMAN              Reviewed;          65 AA.
AC   O75394; Q53RZ6; Q5FVE3; Q96Q50;
DE   RecName: Full=39S ribosomal protein L33, mitochondrial;
DE            Short=L33mt;
DE            Short=MRP-L33;
GN   Name=MRPL33; Synonyms=C2orf1;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM34_HUMAN              Reviewed;          92 AA.
AC   Q9BQ48;
DE   RecName: Full=39S ribosomal protein L34, mitochondrial;
DE            Short=L34mt;
DE            Short=MRP-L34;
DE   Flags: Precursor;
GN   Name=MRPL34;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM30_HUMAN              Reviewed;         161 AA.
AC   Q8TCC3; A6NIC6; D3DVI0; D3DVI3; Q0D2Q7; Q6ZTP4; Q96Q69; Q9P0N0;
DE   RecName: Full=39S ribosomal protein L30, mitochondrial;
DE            Short=L30mt;
DE            Short=MRP-L30;
DE   AltName: Full=39S ribosomal protein L28, mitochondrial;
DE            Short=L28mt;
DE            Short=MRP-L28;
DE   Flags: Precursor;
GN   Name=MRPL30; Synonyms=MRPL28, RPML28; ORFNames=HSPC249;
//
ID   RM35_HUMAN              Reviewed;         188 AA.
AC   Q9NZE8; A6NKV6; B2RB93; Q658U7; Q8WWA2;
DE   RecName: Full=39S ribosomal protein L35, mitochondrial;
DE            Short=L35mt;
DE            Short=MRP-L35;
DE   Flags: Precursor;
GN   Name=MRPL35; ORFNames=BM-007;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM36_HUMAN              Reviewed;         103 AA.
AC   Q9P0J6; A4UCS0; B2R4Z2; Q3SWV6; Q9UKL7;
DE   RecName: Full=39S ribosomal protein L36, mitochondrial;
DE            Short=L36mt;
DE            Short=MRP-L36;
DE   AltName: Full=BRCA1-interacting protein 1;
DE   Flags: Precursor;
GN   Name=MRPL36; Synonyms=BRIP1;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM37_HUMAN              Reviewed;         423 AA.
AC   Q9BZE1; Q96Q67; Q9BWR1; Q9P0P3;
DE   RecName: Full=39S ribosomal protein L37, mitochondrial;
DE            Short=L37mt;
DE            Short=MRP-L37;
DE   AltName: Full=39S ribosomal protein L2, mitochondrial;
DE            Short=L2mt;
DE            Short=MRP-L2;
DE   Flags: Precursor;
GN   Name=MRPL37; Synonyms=MRPL2, RPML2; ORFNames=HSPC235;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM38_HUMAN              Reviewed;         380 AA.
AC   Q96DV4; Q96Q66; Q9P0B9;
DE   RecName: Full=39S ribosomal protein L38, mitochondrial;
DE            Short=L38mt;
DE            Short=MRP-L38;
DE   Flags: Precursor;
GN   Name=MRPL38; ORFNames=HSPC262;
//
ID   RM39_HUMAN              Reviewed;         338 AA.
AC   Q9NYK5; C9JYA5; Q32Q74; Q5QTR3; Q96Q65; Q9BSQ7; Q9BZV6; Q9NX44;
DE   RecName: Full=39S ribosomal protein L39, mitochondrial;
DE            Short=L39mt;
DE            Short=MRP-L39;
DE   AltName: Full=39S ribosomal protein L5, mitochondrial;
DE            Short=L5mt;
DE            Short=MRP-L5;
GN   Name=MRPL39; Synonyms=C21orf92, MRPL5, RPML5;
GN   ORFNames=MSTP003, PRED22;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RM40_HUMAN              Reviewed;         206 AA.
AC   Q9NQ50; B3KVZ7; O95134;
DE   RecName: Full=39S ribosomal protein L40, mitochondrial;
DE            Short=L40mt;
DE            Short=MRP-L40;
DE   AltName: Full=Nuclear localization signal-containing protein deleted in velocardiofacial syndrome;
DE   AltName: Full=Up-regulated in metastasis;
DE   Flags: Precursor;
GN   Name=MRPL40; Synonyms=NLVCF, URIM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
//
ID   RM41_HUMAN              Reviewed;         137 AA.
AC   Q8IXM3; Q96Q49;
DE   RecName: Full=39S ribosomal protein L41, mitochondrial;
DE            Short=L41mt;
DE            Short=MRP-L41;
DE   AltName: Full=39S ribosomal protein L27 homolog;
DE   AltName: Full=Bcl-2-interacting mitochondrial ribosomal protein L41;
DE   AltName: Full=Cell proliferation-inducing gene 3 protein;
DE   AltName: Full=MRP-L27 homolog;
DE   Flags: Precursor;
GN   Name=MRPL41; Synonyms=BMRP, MRPL27, RPML27; ORFNames=PIG3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; IDA:UniProtKB.
//
ID   RM42_HUMAN              Reviewed;         142 AA.
AC   Q9Y6G3; Q6FID1; Q96Q48; Q9P0S1;
DE   RecName: Full=39S ribosomal protein L42, mitochondrial;
DE            Short=L42mt;
DE            Short=MRP-L42;
DE   AltName: Full=28S ribosomal protein S32, mitochondrial;
DE            Short=MRP-S32;
DE            Short=S32mt;
DE   AltName: Full=39S ribosomal protein L31, mitochondrial;
DE            Short=L31mt;
DE            Short=MRP-L31;
DE   Flags: Precursor;
GN   Name=MRPL42; Synonyms=MRPL31, MRPS32, RPML31;
GN   ORFNames=HSPC204, PTD007;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM43_HUMAN              Reviewed;         215 AA.
AC   Q8N983; B1AL06; B1AL07; B1AL09; B1AL10; C9J5Q3; D3DR71; Q5JW06;
AC   Q7Z719; Q7Z7H6; Q86XN1; Q9BYC7;
DE   RecName: Full=39S ribosomal protein L43, mitochondrial;
DE            Short=L43mt;
DE            Short=MRP-L43;
DE   AltName: Full=Mitochondrial ribosomal protein bMRP36a;
DE   Flags: Precursor;
GN   Name=MRPL43;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RM44_HUMAN              Reviewed;         332 AA.
AC   Q9H9J2; Q53S16; Q6IA62; Q9H821;
DE   RecName: Full=39S ribosomal protein L44, mitochondrial;
DE            Short=L44mt;
DE            Short=MRP-L44;
DE            EC=3.1.26.-;
DE   Flags: Precursor;
GN   Name=MRPL44;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0070125; P:mitochondrial translational elongation; IMP:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   RM45_HUMAN              Reviewed;         306 AA.
AC   Q9BRJ2; A1L436; Q6ZMJ5;
DE   RecName: Full=39S ribosomal protein L45, mitochondrial;
DE            Short=L45mt;
DE            Short=MRP-L45;
DE   Flags: Precursor;
GN   Name=MRPL45;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RM46_HUMAN              Reviewed;         279 AA.
AC   Q9H2W6; B2RD75; Q9HBU8;
DE   RecName: Full=39S ribosomal protein L46, mitochondrial;
DE            Short=L46mt;
DE            Short=MRP-L46;
DE   AltName: Full=P2ECSL;
DE   Flags: Precursor;
GN   Name=MRPL46; Synonyms=C15orf4, LIECG2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
//
ID   RM47_HUMAN              Reviewed;         250 AA.
AC   Q9HD33; Q6XRG1; Q8N5D1;
DE   RecName: Full=39S ribosomal protein L47, mitochondrial;
DE            Short=L47mt;
DE            Short=MRP-L47;
DE   AltName: Full=Nasopharyngeal carcinoma metastasis-related protein 1;
DE   Flags: Precursor;
GN   Name=MRPL47; Synonyms=NCM1; ORFNames=CGI-204;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM48_HUMAN              Reviewed;         212 AA.
AC   Q96GC5; B4DN34; Q49AK7; Q4U2Q4; Q9P091; Q9Y5J0;
DE   RecName: Full=39S ribosomal protein L48, mitochondrial;
DE            Short=L48mt;
DE            Short=MRP-L48;
DE   Flags: Precursor;
GN   Name=MRPL48; ORFNames=CGI-118, HSPC290;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   RM49_HUMAN              Reviewed;         166 AA.
AC   Q13405; B2R4G6;
DE   RecName: Full=39S ribosomal protein L49, mitochondrial;
DE            Short=L49mt;
DE            Short=MRP-L49;
DE   AltName: Full=Neighbor of FAU;
DE            Short=NOF;
DE   AltName: Full=Protein NOF1;
GN   Name=MRPL49; Synonyms=C11orf4, NOF1; ORFNames=OK/SW-cl.67;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RM51_HUMAN              Reviewed;         128 AA.
AC   Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7;
DE   RecName: Full=39S ribosomal protein L51, mitochondrial;
DE            Short=L51mt;
DE            Short=MRP-L51;
DE   AltName: Full=bMRP-64;
DE            Short=bMRP64;
DE   Flags: Precursor;
GN   Name=MRPL51; Synonyms=MRP64; ORFNames=CDA09, HSPC241;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
//
ID   RM52_HUMAN              Reviewed;         123 AA.
AC   Q86TS9; A6NMQ8; A8MXK5; A8MYI6; G3XCN9; Q6NVH8;
DE   RecName: Full=39S ribosomal protein L52, mitochondrial;
DE            Short=L52mt;
DE            Short=MRP-L52;
DE   Flags: Precursor;
GN   Name=MRPL52;
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
//
ID   RM50_HUMAN              Reviewed;         158 AA.
AC   Q8N5N7; Q5T7E0; Q9NX15;
DE   RecName: Full=39S ribosomal protein L50, mitochondrial;
DE            Short=L50mt;
DE            Short=MRP-L50;
GN   Name=MRPL50;
//
ID   RM53_HUMAN              Reviewed;         112 AA.
AC   Q96EL3;
DE   RecName: Full=39S ribosomal protein L53, mitochondrial;
DE            Short=L53mt;
DE            Short=MRP-L53;
DE   Flags: Precursor;
GN   Name=MRPL53;
//
ID   RM54_HUMAN              Reviewed;         138 AA.
AC   Q6P161;
DE   RecName: Full=39S ribosomal protein L54, mitochondrial;
DE            Short=L54mt;
DE            Short=MRP-L54;
DE   Flags: Precursor;
GN   Name=MRPL54;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RM55_HUMAN              Reviewed;         128 AA.
AC   Q7Z7F7; Q5TBY3; Q5TBY6; Q6UWI8;
DE   RecName: Full=39S ribosomal protein L55, mitochondrial;
DE            Short=L55mt;
DE            Short=MRP-L55;
DE   Flags: Precursor;
GN   Name=MRPL55; ORFNames=UNQ5835/PRO19675;
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
//
ID   RMD1_HUMAN              Reviewed;         314 AA.
AC   Q96DB5; A9UMZ8; B4DZW6; B5MC61; C9JSC6; Q9Y398;
DE   RecName: Full=Regulator of microtubule dynamics protein 1;
DE            Short=RMD-1;
DE            Short=hRMD-1;
DE   AltName: Full=Protein FAM82B;
GN   Name=RMDN1; Synonyms=FAM82B; ORFNames=CGI-90;
//
ID   RMD2_HUMAN              Reviewed;         410 AA.
AC   Q96LZ7; A9UMZ7; A9UN00; Q4ZG33; Q6UXN4; Q8N657; Q8N9A2; Q8NCV6;
AC   Q8NHM0;
DE   RecName: Full=Regulator of microtubule dynamics protein 2;
DE            Short=RMD-2;
DE            Short=hRMD-2;
DE   AltName: Full=Protein FAM82A1;
GN   Name=RMDN2; Synonyms=FAM82A, FAM82A1;
GN   ORFNames=BLOCK18, UNQ9371/PRO34163;
//
ID   RMD3_HUMAN              Reviewed;         470 AA.
AC   Q96TC7; A9UMZ9; B3KRR3; Q6ZWE9; Q96H23; Q96SD6; Q9H6G1; Q9NVQ6;
DE   RecName: Full=Regulator of microtubule dynamics protein 3;
DE            Short=RMD-3;
DE            Short=hRMD-3;
DE   AltName: Full=Cerebral protein 10;
DE   AltName: Full=Protein FAM82A2;
DE   AltName: Full=Protein FAM82C;
DE   AltName: Full=Protein tyrosine phosphatase-interacting protein 51;
DE   AltName: Full=TCPTP-interacting protein 51;
GN   Name=RMDN3; Synonyms=FAM82A2, FAM82C, PTPIP51;
GN   ORFNames=hucep-10, UNQ3122/PRO10274;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.
//
ID   RMD5B_HUMAN             Reviewed;         393 AA.
AC   Q96G75; Q1HE27; Q6UVY7; Q9H6F6;
DE   RecName: Full=Protein RMD5 homolog B;
GN   Name=RMND5B; ORFNames=UNQ2508/PRO5996;
//
ID   RMD5A_HUMAN             Reviewed;         391 AA.
AC   Q9H871; D6W5M6; Q6NTF0; Q9H6W5; Q9H9H2;
DE   RecName: Full=Protein RMD5 homolog A;
GN   Name=RMND5A;
//
ID   RMI1_HUMAN              Reviewed;         625 AA.
AC   Q9H9A7; Q05BX1; Q05CW3; Q5SQG8; Q5SQG9; Q6P1Q4; Q6PI89; Q7Z6L6;
DE   RecName: Full=RecQ-mediated genome instability protein 1;
DE   AltName: Full=BLM-associated protein of 75 kDa;
DE            Short=BLAP75;
DE   AltName: Full=FAAP75;
GN   Name=RMI1; Synonyms=C9orf76;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   RMI2_HUMAN              Reviewed;         147 AA.
AC   Q96E14; B3KVZ6; Q49AE2; Q8TBL0;
DE   RecName: Full=RecQ-mediated genome instability protein 2;
DE            Short=hRMI2;
DE   AltName: Full=BLM-associated protein of 18 kDa;
DE            Short=BLAP18;
GN   Name=RMI2; Synonyms=C16orf75;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
//
ID   RMND1_HUMAN             Reviewed;         449 AA.
AC   Q9NWS8; A8K8H4; Q0VDG6; Q5SZ48; Q5SZ83; Q6NSC5; Q96EN7;
DE   RecName: Full=Required for meiotic nuclear division protein 1 homolog;
DE   Flags: Precursor;
GN   Name=RMND1; Synonyms=C6orf96;
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
//
ID   RMP_HUMAN               Reviewed;         535 AA.
AC   O94763; A8K805; H7BY42; Q8TC23; Q9UNU3;
DE   RecName: Full=Unconventional prefoldin RPB5 interactor 1;
DE   AltName: Full=Protein NNX3;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 19;
DE   AltName: Full=RNA polymerase II subunit 5-mediating protein;
DE            Short=RPB5-mediating protein;
GN   Name=URI1; Synonyms=C19orf2, NNX3, PPP1R19, RMP, URI;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0001558; P:regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IMP:UniProtKB.
//
ID   RMTL1_HUMAN             Reviewed;         420 AA.
AC   Q9HC36; Q53GN1; Q86VC3; Q96F76; Q9NVQ5;
DE   RecName: Full=RNA methyltransferase-like protein 1;
DE            EC=2.1.1.-;
GN   Name=RNMTL1; ORFNames=HC90;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   RMXL1_HUMAN             Reviewed;         390 AA.
AC   Q96E39;
DE   RecName: Full=RNA binding motif protein, X-linked-like-1;
DE   AltName: Full=Heterogeneous nuclear ribonucleoprotein G-like 1;
GN   Name=RBMXL1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RMXL2_HUMAN             Reviewed;         392 AA.
AC   O75526; Q6PEZ2; Q9NQU0;
DE   RecName: Full=RNA-binding motif protein, X-linked-like-2;
DE   AltName: Full=Testis-specific heterogeneous nuclear ribonucleoprotein G-T;
DE            Short=hnRNP G-T;
GN   Name=RBMXL2; Synonyms=HNRNPGT;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RMXL3_HUMAN             Reviewed;        1067 AA.
AC   Q8N7X1; B4DXC0;
DE   RecName: Full=RNA-binding motif protein, X-linked-like-3;
GN   Name=RBMXL3; Synonyms=CXorf55;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   RN103_HUMAN             Reviewed;         685 AA.
AC   O00237; A6NFV6; Q53SU6; Q8IVB9;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF103;
DE            EC=6.3.2.-;
DE   AltName: Full=KF-1;
DE            Short=hKF-1;
DE   AltName: Full=RING finger protein 103;
DE   AltName: Full=Zinc finger protein 103 homolog;
DE            Short=Zfp-103;
GN   Name=RNF103; Synonyms=ZFP103;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   RN111_HUMAN             Reviewed;         994 AA.
AC   Q6ZNA4; C9JUS4; H0YN55; Q6P9A4; Q6ZMU2; Q7L428; Q7Z346; Q8N1P9;
AC   Q8WUA3; Q9NSR1;
DE   RecName: Full=E3 ubiquitin-protein ligase Arkadia;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 111;
GN   Name=RNF111;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032184; F:SUMO polymer binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IEA:Ensembl.
//
ID   RN112_HUMAN             Reviewed;         631 AA.
AC   Q9ULX5; O60633; Q7Z5V9;
DE   RecName: Full=RING finger protein 112;
DE   AltName: Full=Brain finger protein;
DE   AltName: Full=Zinc finger protein 179;
GN   Name=RNF112; Synonyms=BFP, ZNF179;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
//
ID   RN121_HUMAN             Reviewed;         327 AA.
AC   Q9H920; B3KSW8; Q6IA57; Q6P449; Q96DB4;
DE   RecName: Full=RING finger protein 121;
GN   Name=RNF121;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN115_HUMAN             Reviewed;         304 AA.
AC   Q9Y4L5; A8K3Y4; Q5T2V9; Q7Z2J2;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF115;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 115;
DE   AltName: Full=Rabring 7;
DE   AltName: Full=Zinc finger protein 364;
GN   Name=RNF115; Synonyms=ZNF364;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
//
ID   RN114_HUMAN             Reviewed;         228 AA.
AC   Q9Y508; B2RDQ9; B4DWY5; E1P627; Q6N0B0;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF114;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 114;
DE   AltName: Full=Zinc finger protein 228;
DE   AltName: Full=Zinc finger protein 313;
GN   Name=RNF114; Synonyms=ZNF228, ZNF313;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   RN122_HUMAN             Reviewed;         155 AA.
AC   Q9H9V4; Q52LK3;
DE   RecName: Full=RING finger protein 122;
GN   Name=RNF122;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN125_HUMAN             Reviewed;         232 AA.
AC   Q96EQ8; Q9NX39;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF125;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 125;
DE   AltName: Full=T-cell RING activation protein 1;
DE            Short=TRAC-1;
GN   Name=RNF125;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
//
ID   RN126_HUMAN             Reviewed;         326 AA.
AC   Q9BV68; Q9NWX1;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF126;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 126;
GN   Name=RNF126;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN123_HUMAN             Reviewed;        1314 AA.
AC   Q5XPI4; A1L4Q3; A6NLS5; Q5I022; Q6PFW4; Q71RH0; Q8IW18; Q9H0M8;
AC   Q9H5L8; Q9H9T2;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF123;
DE            EC=6.3.2.-;
DE   AltName: Full=Kip1 ubiquitination-promoting complex protein 1;
DE   AltName: Full=RING finger protein 123;
GN   Name=RNF123; Synonyms=KPC1; ORFNames=FP1477;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN133_HUMAN             Reviewed;         376 AA.
AC   Q8WVZ7; A4D0W2; Q8N7G7;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF133;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 133;
GN   Name=RNF133;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IEA:Ensembl.
//
ID   RN128_HUMAN             Reviewed;         428 AA.
AC   Q8TEB7; A0PJI4; Q6PH80; Q6ZTJ8; Q96RF3; Q9H5E4;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF128;
DE            EC=6.3.2.-;
DE   AltName: Full=Gene related to anergy in lymphocytes protein;
DE            Short=GRAIL;
DE   AltName: Full=RING finger protein 128;
DE   Flags: Precursor;
GN   Name=RNF128;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042036; P:negative regulation of cytokine biosynthetic process; IEA:Ensembl.
//
ID   RN135_HUMAN             Reviewed;         432 AA.
AC   Q8IUD6; A0AVM5; B2R7G9; B6ZLM5; F5GX60; Q9BSE9;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF135;
DE            EC=6.3.2.-;
DE   AltName: Full=RIG-I E3 ubiquitin ligase;
DE            Short=REUL;
DE   AltName: Full=RING finger protein 135;
DE   AltName: Full=Riplet;
GN   Name=RNF135; ORFNames=L13;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; IMP:UniProtKB.
//
ID   RN138_HUMAN             Reviewed;         245 AA.
AC   Q8WVD3; B2RE17; Q9H8K2; Q9UF87; Q9UKI6;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF138;
DE            EC=6.3.2.-;
DE   AltName: Full=Nemo-like kinase-associated RING finger protein;
DE            Short=NLK-associated RING finger protein;
DE            Short=hNARF;
DE   AltName: Full=RING finger protein 138;
GN   Name=RNF138; Synonyms=NARF; ORFNames=HSD-4, HSD4;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RN139_HUMAN             Reviewed;         664 AA.
AC   Q8WU17; B3KMD5; O75485; Q7LDL3;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF139;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 139;
DE   AltName: Full=Translocation in renal carcinoma on chromosome 8 protein;
GN   Name=RNF139; Synonyms=TRC8;
DR   GO; GO:0016874; F:ligase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:UniProtKB.
DR   GO; GO:0019787; F:small conjugating protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0070613; P:regulation of protein processing; IDA:UniProtKB.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
//
ID   RN145_HUMAN             Reviewed;         663 AA.
AC   Q96MT1; B7Z903; B7Z949; E7EVI7; Q8IVP7;
DE   RecName: Full=RING finger protein 145;
GN   Name=RNF145;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN141_HUMAN             Reviewed;         230 AA.
AC   Q8WVD5; A8K149; Q9NZB4;
DE   RecName: Full=RING finger protein 141;
DE   AltName: Full=Zinc finger protein 230;
GN   Name=RNF141; Synonyms=ZNF230;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   RN146_HUMAN             Reviewed;         359 AA.
AC   Q9NTX7; E1P572; Q6FIB2; Q7L8H4; Q96K03; Q96T06; Q9NTX6;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF146;
DE            EC=6.3.2.-;
DE   AltName: Full=Dactylidin;
DE   AltName: Full=Iduna;
DE   AltName: Full=RING finger protein 146;
GN   Name=RNF146;
DR   GO; GO:0072572; F:poly-ADP-D-ribose binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IMP:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RN149_HUMAN             Reviewed;         400 AA.
AC   Q8NC42; Q53S14; Q8N5I8; Q8NBY5; Q8WUU3;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF149;
DE            EC=6.3.2.-;
DE   AltName: Full=DNA polymerase-transactivated protein 2;
DE   AltName: Full=RING finger protein 149;
DE   Flags: Precursor;
GN   Name=RNF149; Synonyms=DNAPTP2;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN150_HUMAN             Reviewed;         438 AA.
AC   Q9ULK6; Q3T1D0; Q6ZNW6;
DE   RecName: Full=RING finger protein 150;
DE   Flags: Precursor;
GN   Name=RNF150; Synonyms=KIAA1214;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN148_HUMAN             Reviewed;         305 AA.
AC   Q8N7C7; Q8N308;
DE   RecName: Full=RING finger protein 148;
DE   Flags: Precursor;
GN   Name=RNF148;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN152_HUMAN             Reviewed;         203 AA.
AC   Q8N8N0; B3KV99; Q52LA4;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF152;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 152;
GN   Name=RNF152;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
//
ID   RN151_HUMAN             Reviewed;         245 AA.
AC   Q2KHN1; Q8NHS5;
DE   RecName: Full=RING finger protein 151;
GN   Name=RNF151;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   RN166_HUMAN             Reviewed;         237 AA.
AC   Q96A37; B3KQ03; D3DX75; H3BTU8; Q96DM0;
DE   RecName: Full=RING finger protein 166;
GN   Name=RNF166;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN165_HUMAN             Reviewed;         346 AA.
AC   Q6ZSG1; B3KVD1;
DE   RecName: Full=RING finger protein 165;
GN   Name=RNF165;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN167_HUMAN             Reviewed;         350 AA.
AC   Q9H6Y7; D3DTK8; Q6XYE0; Q8NDC1; Q9Y3V1;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF167;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 167;
DE   AltName: Full=RING105;
DE   Flags: Precursor;
GN   Name=RNF167; ORFNames=LP2254;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
//
ID   RN157_HUMAN             Reviewed;         679 AA.
AC   Q96PX1; Q8NB72; Q96N56;
DE   RecName: Full=RING finger protein 157;
GN   Name=RNF157; Synonyms=KIAA1917;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN168_HUMAN             Reviewed;         571 AA.
AC   Q8IYW5; Q8NA67; Q96NS4;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF168;
DE            Short=hRNF168;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 168;
GN   Name=RNF168;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031491; F:nucleosome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0070535; P:histone H2A K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0036351; P:histone H2A-K13 ubiquitination; IDA:UniProtKB.
DR   GO; GO:0036352; P:histone H2A-K15 ubiquitination; IDA:UniProtKB.
DR   GO; GO:0036297; P:interstrand cross-link repair; TAS:UniProtKB.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0045900; P:negative regulation of translational elongation; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   RN169_HUMAN             Reviewed;         708 AA.
AC   Q8NCN4; Q6N015;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF169;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 169;
GN   Name=RNF169; Synonyms=KIAA1991;
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031491; F:nucleosome binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:2000780; P:negative regulation of double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN170_HUMAN             Reviewed;         258 AA.
AC   Q96K19; D3DSY6; E9PIL4; Q7Z483; Q86YC0; Q8IXR7; Q8N2B5; Q8N5G9;
AC   Q8NG30; Q9H0V6;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF170;
DE            EC=6.3.2.-;
DE   AltName: Full=Putative LAG1-interacting protein;
DE   AltName: Full=RING finger protein 170;
GN   Name=RNF170;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN175_HUMAN             Reviewed;         328 AA.
AC   Q8N4F7;
DE   RecName: Full=RING finger protein 175;
GN   Name=RNF175;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN180_HUMAN             Reviewed;         592 AA.
AC   Q86T96; Q0JSU3; Q495A8; Q8NBD1;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF180;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 180;
GN   Name=RNF180;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   RN181_HUMAN             Reviewed;         153 AA.
AC   Q9P0P0; Q53H81;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF181;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 181;
GN   Name=RNF181; ORFNames=HSPC238;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
//
ID   RN182_HUMAN             Reviewed;         247 AA.
AC   Q8N6D2; B2RDG2; Q8NBG3;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF182;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 182;
GN   Name=RNF182;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   RN183_HUMAN             Reviewed;         192 AA.
AC   Q96D59;
DE   RecName: Full=RING finger protein 183;
GN   Name=RNF183;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN185_HUMAN             Reviewed;         192 AA.
AC   Q96GF1; A8K5C1; A9X3T8; Q8N900;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF185;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 185;
GN   Name=RNF185;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN186_HUMAN             Reviewed;         227 AA.
AC   Q9NXI6; Q53GE0;
DE   RecName: Full=RING finger protein 186;
GN   Name=RNF186;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN187_HUMAN             Reviewed;         235 AA.
AC   Q5TA31; A6NL57; Q6P2J7; Q6PJR0;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF187;
DE            EC=6.3.2.-;
DE   AltName: Full=RING domain AP1 coactivator 1;
DE            Short=RACO-1;
DE   AltName: Full=RING finger protein 187;
GN   Name=RNF187;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IMP:UniProtKB.
//
ID   RN19A_HUMAN             Reviewed;         838 AA.
AC   Q9NV58; A3KCU9; Q52LG1; Q9H5H9; Q9H8M8; Q9UFG0; Q9UFX6; Q9Y4Y1;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF19A;
DE            EC=6.3.2.-;
DE   AltName: Full=Double ring-finger protein;
DE            Short=Dorfin;
DE   AltName: Full=RING finger protein 19A;
DE   AltName: Full=p38;
GN   Name=RNF19A; Synonyms=RNF19;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008134; F:transcription factor binding; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN207_HUMAN             Reviewed;         634 AA.
AC   Q6ZRF8; A2VCM8; B4DFR6; Q5TGS6; Q6ZS63; Q96MP2;
DE   RecName: Full=RING finger protein 207;
GN   Name=RNF207; Synonyms=C1orf188;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN208_HUMAN             Reviewed;         261 AA.
AC   Q9H0X6; A2BFA0;
DE   RecName: Full=RING finger protein 208;
GN   Name=RNF208;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
//
ID   RN213_HUMAN             Reviewed;        5207 AA.
AC   Q63HN8; C9JCP4; D6RI12; F8WKS1; Q658P6; Q69YK7; Q6MZR1; Q8IWF4;
AC   Q8IZX1; Q8IZX2; Q8N406; Q8TEU0; Q9H6C9; Q9H6H9; Q9H6P3; Q9H8A9;
AC   Q9HCF4; Q9HCL8;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF213;
DE            EC=6.3.2.-;
DE   AltName: Full=ALK lymphoma oligomerization partner on chromosome 17;
DE   AltName: Full=Mysterin;
DE   AltName: Full=RING finger protein 213;
GN   Name=RNF213; Synonyms=ALO17, C17orf27, KIAA1554, KIAA1618, MYSTR;
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   RN19B_HUMAN             Reviewed;         732 AA.
AC   Q6ZMZ0; B7ZLB2; E9PAW6; G3XA82; Q0VG77; Q5TH44; Q5TH45; Q6P6A4;
AC   Q8N2S8; Q8WUF3;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF19B;
DE            EC=6.3.2.-;
DE   AltName: Full=IBR domain-containing protein 3;
DE   AltName: Full=Natural killer lytic-associated molecule;
DE   AltName: Full=RING finger protein 19B;
GN   Name=RNF19B; Synonyms=IBRDC3, NKLAM;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0072643; P:interferon-gamma secretion; IEA:Ensembl.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   RN212_HUMAN             Reviewed;         297 AA.
AC   Q495C1; C9J8N0; Q495C0; Q86W82; Q8IY99; Q8N8U7;
DE   RecName: Full=Probable E3 SUMO-protein ligase RNF212;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 212;
GN   Name=RNF212;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051026; P:chiasma assembly; ISS:UniProtKB.
DR   GO; GO:0006311; P:meiotic gene conversion; ISS:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.
//
ID   RN215_HUMAN             Reviewed;         377 AA.
AC   Q9Y6U7; A6NEL1;
DE   RecName: Full=RING finger protein 215;
GN   Name=RNF215;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN214_HUMAN             Reviewed;         703 AA.
AC   Q8ND24; B2RUW0; B4DTD1;
DE   RecName: Full=RING finger protein 214;
GN   Name=RNF214;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN219_HUMAN             Reviewed;         726 AA.
AC   Q5W0B1; B2RN99; Q8TBY2; Q9H0T2; Q9H8M0;
DE   RecName: Full=RING finger protein 219;
GN   Name=RNF219; Synonyms=C13orf7;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN216_HUMAN             Reviewed;         866 AA.
AC   Q9NWF9; Q6Y691; Q75ML7; Q7Z2H7; Q7Z7C1; Q8NHW7; Q9NYT1;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF216;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 216;
DE   AltName: Full=Triad domain-containing protein 3;
DE   AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 1;
DE   AltName: Full=Zinc finger protein inhibiting NF-kappa-B;
GN   Name=RNF216; Synonyms=TRIAD3, UBCE7IP1, ZIN;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0050691; P:regulation of defense response to virus by host; IDA:UniProtKB.
DR   GO; GO:0032648; P:regulation of interferon-beta production; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RN220_HUMAN             Reviewed;         566 AA.
AC   Q5VTB9; B3KPJ3; Q4KMX2; Q9NVP6;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF220;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 220;
GN   Name=RNF220; Synonyms=C1orf164;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   RN224_HUMAN             Reviewed;         156 AA.
AC   P0DH78;
DE   RecName: Full=RING finger protein 224;
GN   Name=RNF224;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN222_HUMAN             Reviewed;         220 AA.
AC   A6NCQ9;
DE   RecName: Full=RING finger protein 222;
GN   Name=RNF222;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN223_HUMAN             Reviewed;         249 AA.
AC   E7ERA6; B4DKI4;
DE   RecName: Full=RING finger protein 223;
GN   Name=RNF223;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RN217_HUMAN             Reviewed;         542 AA.
AC   Q8TC41; H7C5V4; Q5TCA4; Q9BX48;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase RNF217;
DE            EC=6.3.2.-;
DE   AltName: Full=IBR domain-containing protein 1;
DE   AltName: Full=RING finger protein 217;
GN   Name=RNF217; Synonyms=C6orf172, IBRDC1;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   RN3P2_HUMAN             Reviewed;         340 AA.
AC   A6NIE6;
DE   RecName: Full=Putative RRN3-like protein RRN3P2;
DE   AltName: Full=RNA polymerase I transcription factor homolog pseudogene 2;
GN   Name=RRN3P2;
//
ID   RN5A_HUMAN              Reviewed;         741 AA.
AC   Q05823; Q5W0L2;
DE   RecName: Full=2-5A-dependent ribonuclease;
DE            Short=2-5A-dependent RNase;
DE            EC=3.1.26.-;
DE   AltName: Full=Ribonuclease 4;
DE   AltName: Full=Ribonuclease L;
DE            Short=RNase L;
GN   Name=RNASEL; Synonyms=RNS4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; NAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   RN3P1_HUMAN             Reviewed;         152 AA.
AC   Q2M238; A8K6T4; B3KWX9; O75704;
DE   RecName: Full=Putative RRN3-like protein RRN3P1;
DE   AltName: Full=RNA polymerase I transcription factor homolog pseudogene 1;
GN   Name=RRN3P1;
//
ID   RNAS1_HUMAN             Reviewed;         156 AA.
AC   P07998; B2R589; D3DS06; Q16830; Q16869; Q1KHR2; Q6ICS5; Q9UCB4;
AC   Q9UCB5;
DE   RecName: Full=Ribonuclease pancreatic;
DE            EC=3.1.27.5;
DE   AltName: Full=HP-RNase;
DE   AltName: Full=RIB-1;
DE   AltName: Full=RNase UpI-1;
DE   AltName: Full=Ribonuclease 1;
DE            Short=RNase 1;
DE   AltName: Full=Ribonuclease A;
DE            Short=RNase A;
DE   Flags: Precursor;
GN   Name=RNASE1; Synonyms=RIB1, RNS1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004522; F:pancreatic ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
//
ID   RNAS2_HUMAN             Reviewed;         161 AA.
AC   P10153; Q52M39; Q9H2B7; Q9UCG7;
DE   RecName: Full=Non-secretory ribonuclease;
DE            EC=3.1.27.5;
DE   AltName: Full=Eosinophil-derived neurotoxin;
DE   AltName: Full=RNase UpI-2;
DE   AltName: Full=Ribonuclease 2;
DE            Short=RNase 2;
DE   AltName: Full=Ribonuclease US;
DE   Flags: Precursor;
GN   Name=RNASE2; Synonyms=EDN, RNS2;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004522; F:pancreatic ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0004540; F:ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
//
ID   RNAS4_HUMAN             Reviewed;         147 AA.
AC   P34096;
DE   RecName: Full=Ribonuclease 4;
DE            Short=RNase 4;
DE            EC=3.1.27.-;
DE   Flags: Precursor;
GN   Name=RNASE4; Synonyms=RNS4;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004522; F:pancreatic ribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0006379; P:mRNA cleavage; NAS:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; NAS:GOC.
//
ID   RNAS6_HUMAN             Reviewed;         150 AA.
AC   Q93091;
DE   RecName: Full=Ribonuclease K6;
DE            Short=RNase K6;
DE            EC=3.1.27.-;
DE   Flags: Precursor;
GN   Name=RNASE6; Synonyms=RNS6;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004540; F:ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
//
ID   RNAS7_HUMAN             Reviewed;         156 AA.
AC   Q9H1E1; P80927; P83685; Q546N3;
DE   RecName: Full=Ribonuclease 7;
DE            Short=RNase 7;
DE            EC=3.1.27.-;
DE   AltName: Full=Skin-derived antimicrobial protein 2;
DE            Short=SAP-2;
DE   Flags: Precursor;
GN   Name=RNASE7; ORFNames=UNQ2516/PRO6006;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004540; F:ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; NAS:UniProtKB.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
//
ID   RNAS8_HUMAN             Reviewed;         154 AA.
AC   Q8TDE3; B2RPP6; B2RPP7;
DE   RecName: Full=Ribonuclease 8;
DE            Short=RNase 8;
DE            EC=3.1.27.-;
DE   Flags: Precursor;
GN   Name=RNASE8;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004522; F:pancreatic ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
//
ID   RNAS9_HUMAN             Reviewed;         205 AA.
AC   P60153; A2RQR8; A8QJS1; Q5GAN7; Q6KG53;
DE   RecName: Full=Inactive ribonuclease-like protein 9;
DE   Flags: Precursor;
GN   Name=RNASE9;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   RNB3L_HUMAN             Reviewed;         465 AA.
AC   Q86VV4; B7Z866; E9PGP9; Q96LK2;
DE   RecName: Full=Ran-binding protein 3-like;
GN   Name=RANBP3L;
DR   GO; GO:0046907; P:intracellular transport; IEA:InterPro.
//
ID   RNBP6_HUMAN             Reviewed;        1105 AA.
AC   O60518; Q5T7X4; Q7Z3V2; Q96E78;
DE   RecName: Full=Ran-binding protein 6;
DE            Short=RanBP6;
GN   Name=RANBP6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   RNC_HUMAN               Reviewed;        1374 AA.
AC   Q9NRR4; E7EMP9; Q7Z5V2; Q86YH0; Q9NW73; Q9Y2V9; Q9Y4Y0;
DE   RecName: Full=Ribonuclease 3;
DE            EC=3.1.26.3;
DE   AltName: Full=Protein Drosha;
DE   AltName: Full=Ribonuclease III;
DE            Short=RNase III;
DE   AltName: Full=p241;
GN   Name=DROSHA; Synonyms=RN3, RNASE3L, RNASEN;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004525; F:ribonuclease III activity; IDA:WormBase.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0010586; P:miRNA metabolic process; IEA:Ensembl.
DR   GO; GO:0031054; P:pre-miRNA processing; IEA:Ensembl.
DR   GO; GO:0031053; P:primary miRNA processing; IDA:WormBase.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:InterPro.
//
ID   RND1_HUMAN              Reviewed;         232 AA.
AC   Q92730; A8K9P7;
DE   RecName: Full=Rho-related GTP-binding protein Rho6;
DE   AltName: Full=Rho family GTPase 1;
DE   AltName: Full=Rnd1;
DE   Flags: Precursor;
GN   Name=RND1; Synonyms=RHO6;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0016322; P:neuron remodeling; IDA:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RND2_HUMAN              Reviewed;         227 AA.
AC   P52198; A8K2D4; O00690; O00734; Q5U0P6; Q99535;
DE   RecName: Full=Rho-related GTP-binding protein RhoN;
DE   AltName: Full=Rho family GTPase 2;
DE   AltName: Full=Rho-related GTP-binding protein Rho7;
DE   AltName: Full=Rnd2;
DE   Flags: Precursor;
GN   Name=RND2; Synonyms=ARHN, RHO7;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0048672; P:positive regulation of collateral sprouting; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RND3_HUMAN              Reviewed;         244 AA.
AC   P61587; D3DP95; P52199;
DE   RecName: Full=Rho-related GTP-binding protein RhoE;
DE   AltName: Full=Protein MemB;
DE   AltName: Full=Rho family GTPase 3;
DE   AltName: Full=Rho-related GTP-binding protein Rho8;
DE   AltName: Full=Rnd3;
DE   Flags: Precursor;
GN   Name=RND3; Synonyms=ARHE, RHO8, RHOE;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RNF10_HUMAN             Reviewed;         811 AA.
AC   Q8N5U6; Q92550; Q9NPP8; Q9ULW4;
DE   RecName: Full=RING finger protein 10;
GN   Name=RNF10; Synonyms=KIAA0262, RIE2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:UniProtKB.
DR   GO; GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RNF11_HUMAN             Reviewed;         154 AA.
AC   Q9Y3C5; A8KAI2; Q5T7R8;
DE   RecName: Full=RING finger protein 11;
GN   Name=RNF11; ORFNames=CGI-123;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   RNF12_HUMAN             Reviewed;         624 AA.
AC   Q9NVW2; D3DTE0; Q96D38; Q9Y598;
DE   RecName: Full=E3 ubiquitin-protein ligase RLIM;
DE            EC=6.3.2.-;
DE   AltName: Full=LIM domain-interacting RING finger protein;
DE   AltName: Full=RING finger LIM domain-binding protein;
DE            Short=R-LIM;
DE   AltName: Full=RING finger protein 12;
DE   AltName: Full=Renal carcinoma antigen NY-REN-43;
GN   Name=RLIM; Synonyms=RNF12;
DR   GO; GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
DR   GO; GO:0060816; P:random inactivation of X chromosome; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   RNF13_HUMAN             Reviewed;         381 AA.
AC   O43567; Q6IBJ9;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF13;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 13;
DE   Flags: Precursor;
GN   Name=RNF13; Synonyms=RZF;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
//
ID   RNF14_HUMAN             Reviewed;         474 AA.
AC   Q9UBS8; A0AV26; A6NMR2; A8MTW5; B3KN72; B7ZLV2; D3DQE4; O94793;
AC   Q6IBV0;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF14;
DE            EC=6.3.2.-;
DE   AltName: Full=Androgen receptor-associated protein 54;
DE   AltName: Full=HFB30;
DE   AltName: Full=RING finger protein 14;
DE   AltName: Full=Triad2 protein;
GN   Name=RNF14; Synonyms=ARA54; ORFNames=HRIHFB2038;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019787; F:small conjugating protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEP:UniProtKB.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RNF17_HUMAN             Reviewed;        1623 AA.
AC   Q9BXT8; Q5T2J9; Q6P1W3; Q9BXT7; Q9NUY9;
DE   RecName: Full=RING finger protein 17;
DE   AltName: Full=Tudor domain-containing protein 4;
GN   Name=RNF17; Synonyms=TDRD4;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   RNF24_HUMAN             Reviewed;         148 AA.
AC   Q9Y225; D3DVZ2; D3DVZ3; Q9UMH1;
DE   RecName: Full=RING finger protein 24;
GN   Name=RNF24;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RNF26_HUMAN             Reviewed;         433 AA.
AC   Q9BY78; Q542Y8;
DE   RecName: Full=RING finger protein 26;
GN   Name=RNF26;
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
//
ID   RNF25_HUMAN             Reviewed;         459 AA.
AC   Q96BH1; A8K0D6; Q53HQ5; Q9H874;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF25;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 25;
GN   Name=RNF25;
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   RNF31_HUMAN             Reviewed;        1072 AA.
AC   Q96EP0; A0A962; Q86VI2; Q8TEI0; Q96GB4; Q96NF1; Q9H5F1; Q9NWD2;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF31;
DE            EC=6.3.2.-;
DE   AltName: Full=HOIL-1-interacting protein;
DE            Short=HOIP;
DE   AltName: Full=RING finger protein 31;
DE   AltName: Full=Zinc in-between-RING-finger ubiquitin-associated domain protein;
GN   Name=RNF31; Synonyms=ZIBRA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0023035; P:CD40 signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.
//
ID   RNF32_HUMAN             Reviewed;         362 AA.
AC   Q9H0A6; Q6FIB3; Q6X7T4; Q8N6V8; Q8TDG0; Q96BM5; Q9Y6U1;
DE   RecName: Full=RING finger protein 32;
GN   Name=RNF32; ORFNames=FKSG33, HSD15;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RNF34_HUMAN             Reviewed;         372 AA.
AC   Q969K3; B7Z933; Q8NG47; Q9H6W8;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF34;
DE            EC=6.3.2.-;
DE   AltName: Full=Caspase regulator CARP1;
DE   AltName: Full=Caspases-8 and -10-associated RING finger protein 1;
DE            Short=CARP-1;
DE   AltName: Full=FYVE-RING finger protein Momo;
DE   AltName: Full=Human RING finger homologous to inhibitor of apoptosis protein;
DE            Short=hRFI;
DE   AltName: Full=RING finger protein 34;
DE   AltName: Full=RING finger protein RIFF;
GN   Name=RNF34;
DR   GO; GO:1901981; F:phosphatidylinositol phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:2001271; P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; IMP:UniProtKB.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
//
ID   RNF37_HUMAN             Reviewed;         541 AA.
AC   O94941; Q6IAR5; Q86X87; Q9H4J2;
DE   RecName: Full=RING finger protein 37;
DE   AltName: Full=U-box domain-containing protein 5;
DE   AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 5;
GN   Name=UBOX5; Synonyms=KIAA0860, RNF37, UBCE7IP5;
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
//
ID   RNF38_HUMAN             Reviewed;         515 AA.
AC   Q9H0F5; A6PVP9; B1AM81; B1AM82; B3KSG4; E7EVL3; Q7LB33; Q8N0Y0;
AC   Q9H748;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF38;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 38;
GN   Name=RNF38;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:FlyBase.
//
ID   RNF39_HUMAN             Reviewed;         420 AA.
AC   Q9H2S5; A2BEK3; A6NCD6; B0S858; Q5SPM8; Q5SPM9; Q5SPN0; Q5SRJ9;
AC   Q5SRK1; Q5SS29; Q9H2S3; Q9H2S4;
DE   RecName: Full=RING finger protein 39;
DE   AltName: Full=Protein HZFw;
GN   Name=RNF39; Synonyms=HZFW;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RNF41_HUMAN             Reviewed;         317 AA.
AC   Q9H4P4; A6NFW0; B2RBT8; O75598;
DE   RecName: Full=E3 ubiquitin-protein ligase NRDP1;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 41;
GN   Name=RNF41; Synonyms=FLRF, NRDP1; ORFNames=SBBI03;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031386; F:protein tag; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:MGI.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0045619; P:regulation of lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IDA:MGI.
DR   GO; GO:0045637; P:regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IDA:MGI.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
//
ID   RNF43_HUMAN             Reviewed;         783 AA.
AC   Q68DV7; A8K4R2; B7Z443; B7Z5D5; B7Z5J5; Q65ZA4; Q6AI04; Q9NXD0;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF43;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 43;
DE   Flags: Precursor;
GN   Name=RNF43;
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0072089; P:stem cell proliferation; ISS:UniProtKB.
DR   GO; GO:0038018; P:Wnt receptor catabolic process; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RNF44_HUMAN             Reviewed;         432 AA.
AC   Q7L0R7; Q8ND05; Q9UPQ2;
DE   RecName: Full=RING finger protein 44;
GN   Name=RNF44; Synonyms=KIAA1100;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RNF4_HUMAN              Reviewed;         190 AA.
AC   P78317; B2R6D6; D6RF58; Q49AR8;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF4;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 4;
DE   AltName: Full=Small nuclear ring finger protein;
DE            Short=Protein SNURF;
GN   Name=RNF4; Synonyms=SNURF; ORFNames=RES4-26;
DR   GO; GO:0050681; F:androgen receptor binding; NAS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0031491; F:nucleosome binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0090234; P:regulation of kinetochore assembly; IMP:UniProtKB.
DR   GO; GO:0090169; P:regulation of spindle assembly; IMP:UniProtKB.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RNF5_HUMAN              Reviewed;         180 AA.
AC   Q99942; A2BFI6; B2R4K3; Q0VDB7; Q9UMQ2;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF5;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein G16;
DE   AltName: Full=RING finger protein 5;
DE   AltName: Full=Ram1 homolog;
DE            Short=HsRma1;
GN   Name=RNF5; Synonyms=G16, NG2, RMA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0044257; P:cellular protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
//
ID   RNF6_HUMAN              Reviewed;         685 AA.
AC   Q9Y252; Q5W0H0; Q9UF41;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF6;
DE            EC=6.3.2.-;
GN   Name=RNF6; Synonyms=SPG2;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030517; P:negative regulation of axon extension; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   RNF8_HUMAN              Reviewed;         485 AA.
AC   O76064; A6NN24; A8MYC0; B4DPG0; Q53H16; Q5NKW5;
DE   RecName: Full=E3 ubiquitin-protein ligase RNF8;
DE            Short=hRNF8;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 8;
GN   Name=RNF8; Synonyms=KIAA0646;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; ISS:UniProtKB.
DR   GO; GO:0043486; P:histone exchange; ISS:UniProtKB.
DR   GO; GO:0070535; P:histone H2A K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.
DR   GO; GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.
DR   GO; GO:0036297; P:interstrand cross-link repair; TAS:UniProtKB.
DR   GO; GO:0045190; P:isotype switching; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0045900; P:negative regulation of translational elongation; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   RNFT1_HUMAN             Reviewed;         435 AA.
AC   Q5M7Z0; Q8N7D0; Q96IZ9; Q9Y686;
DE   RecName: Full=RING finger and transmembrane domain-containing protein 1;
DE   AltName: Full=Protein PTD016;
GN   Name=RNFT1; ORFNames=PTD016;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RNFT2_HUMAN             Reviewed;         444 AA.
AC   Q96EX2; E9PAM7; Q96SU5;
DE   RecName: Full=RING finger and transmembrane domain-containing protein 2;
DE   AltName: Full=Transmembrane protein 118;
GN   Name=RNFT2; Synonyms=TMEM118;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RNH1_HUMAN              Reviewed;         286 AA.
AC   O60930; B3KQU4; O60523; O60857; Q57Z93; Q5U0C1; Q6FHD4;
DE   RecName: Full=Ribonuclease H1;
DE            Short=RNase H1;
DE            EC=3.1.26.4;
DE   AltName: Full=Ribonuclease H type II;
GN   Name=RNASEH1; Synonyms=RNH1;
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0004540; F:ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0006264; P:mitochondrial DNA replication; IEA:Ensembl.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
//
ID   RNH2A_HUMAN             Reviewed;         299 AA.
AC   O75792; B2RCY1; Q96F11;
DE   RecName: Full=Ribonuclease H2 subunit A;
DE            Short=RNase H2 subunit A;
DE            EC=3.1.26.4;
DE   AltName: Full=Aicardi-Goutieres syndrome 4 protein;
DE            Short=AGS4;
DE   AltName: Full=RNase H(35);
DE   AltName: Full=Ribonuclease HI large subunit;
DE            Short=RNase HI large subunit;
DE   AltName: Full=Ribonuclease HI subunit A;
GN   Name=RNASEH2A; Synonyms=RNASEHI, RNHIA;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004540; F:ribonuclease activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:UniProtKB.
DR   GO; GO:0006298; P:mismatch repair; IDA:MGI.
DR   GO; GO:0006401; P:RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
//
ID   RNH2B_HUMAN             Reviewed;         312 AA.
AC   Q5TBB1; G3XAJ1; Q05DR2; Q6PK48; Q9HAF7;
DE   RecName: Full=Ribonuclease H2 subunit B;
DE            Short=RNase H2 subunit B;
DE   AltName: Full=Aicardi-Goutieres syndrome 2 protein;
DE            Short=AGS2;
DE   AltName: Full=Deleted in lymphocytic leukemia 8;
DE   AltName: Full=Ribonuclease HI subunit B;
GN   Name=RNASEH2B; Synonyms=DLEU8;
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:2000001; P:regulation of DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0009259; P:ribonucleotide metabolic process; IEA:Ensembl.
DR   GO; GO:0006401; P:RNA catabolic process; IDA:UniProtKB.
//
ID   RNH2C_HUMAN             Reviewed;         164 AA.
AC   Q8TDP1; Q9H7F5;
DE   RecName: Full=Ribonuclease H2 subunit C;
DE            Short=RNase H2 subunit C;
DE   AltName: Full=Aicardi-Goutieres syndrome 3 protein;
DE            Short=AGS3;
DE   AltName: Full=RNase H1 small subunit;
DE   AltName: Full=Ribonuclease HI subunit C;
GN   Name=RNASEH2C; Synonyms=AYP1;
DR   GO; GO:0006401; P:RNA catabolic process; IDA:UniProtKB.
//
ID   RNK_HUMAN               Reviewed;         137 AA.
AC   Q6P5S7; G3V1Z9; Q502Z2;
DE   RecName: Full=Ribonuclease kappa;
DE            Short=RNase K;
DE            Short=RNase kappa;
DE            EC=3.1.-.-;
GN   Name=RNASEK;
DR   GO; GO:0004521; F:endoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; IDA:GOC.
DR   GO; GO:0009303; P:rRNA transcription; IDA:UniProtKB.
//
ID   RNLS_HUMAN              Reviewed;         342 AA.
AC   Q5VYX0; Q9BS33; Q9NUP8;
DE   RecName: Full=Renalase;
DE            EC=1.6.3.5;
DE   AltName: Full=Monoamine oxidase-C;
DE            Short=MAO-C;
DE   AltName: Full=alpha-NAD(P)H oxidase/anomerase;
DE   Flags: Precursor;
GN   Name=RNLS; Synonyms=C10orf59;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071871; P:response to epinephrine; IEA:Ensembl.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:1902074; P:response to salt; IEA:Ensembl.
//
ID   RNPL1_HUMAN             Reviewed;         494 AA.
AC   Q9HAU8; Q5XKC3; Q6NX56; Q96AC9; Q9H033; Q9NVD0;
DE   RecName: Full=Arginyl aminopeptidase-like 1;
DE            Short=RNPEP-like 1;
DE            EC=3.4.11.-;
GN   Name=RNPEPL1;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019370; P:leukotriene biosynthetic process; IEA:InterPro.
//
ID   RNPS1_HUMAN             Reviewed;         305 AA.
AC   Q15287; A8K1P0; B4DDU8; B4DZU7; B7ZA17; O75308; Q32P25; Q8WY42;
AC   Q9NYG3;
DE   RecName: Full=RNA-binding protein with serine-rich domain 1;
DE   AltName: Full=SR-related protein LDC2;
GN   Name=RNPS1; Synonyms=LDC2;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   RNS10_HUMAN             Reviewed;         216 AA.
AC   Q5GAN6; A2RUQ3; B4DKY4;
DE   RecName: Full=Inactive ribonuclease-like protein 10;
DE   Flags: Precursor;
GN   Name=RNASE10;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0034113; P:heterotypic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:1902093; P:positive regulation of sperm motility; ISS:UniProtKB.
DR   GO; GO:0080154; P:regulation of fertilization; ISS:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
//
ID   RNS11_HUMAN             Reviewed;         199 AA.
AC   Q8TAA1;
DE   RecName: Full=Probable ribonuclease 11;
DE            Short=RNase 11;
DE            EC=3.1.27.-;
DE   Flags: Precursor;
GN   Name=RNASE11; Synonyms=C14orf6; ORFNames=UNQ5832/PRO19669;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   RNS12_HUMAN             Reviewed;         147 AA.
AC   Q5GAN4;
DE   RecName: Full=Probable inactive ribonuclease-like protein 12;
DE   Flags: Precursor;
GN   Name=RNASE12;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   RNS13_HUMAN             Reviewed;         156 AA.
AC   Q5GAN3;
DE   RecName: Full=Probable inactive ribonuclease-like protein 13;
DE   Flags: Precursor;
GN   Name=RNASE13;
DR   GO; GO:0016892; F:endoribonuclease activity, producing 3'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   RNT2_HUMAN              Reviewed;         256 AA.
AC   O00584; B2RDA7; E1P5C3; Q5T8Q0; Q8TCU2; Q9BZ46; Q9BZ47;
DE   RecName: Full=Ribonuclease T2;
DE            EC=3.1.27.-;
DE   AltName: Full=Ribonuclease 6;
DE   Flags: Precursor;
GN   Name=RNASET2; Synonyms=RNASE6PL;
DR   GO; GO:0004540; F:ribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0033897; F:ribonuclease T2 activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0006401; P:RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; IDA:GOC.
//
ID   RNZ1_HUMAN              Reviewed;         363 AA.
AC   Q9H777; Q9NS99;
DE   RecName: Full=Zinc phosphodiesterase ELAC protein 1;
DE            EC=3.1.26.11;
DE   AltName: Full=Deleted in Ma29;
DE   AltName: Full=ElaC homolog protein 1;
DE   AltName: Full=Ribonuclease Z 1;
DE            Short=RNase Z 1;
DE   AltName: Full=tRNA 3 endonuclease 1;
DE   AltName: Full=tRNase Z 1;
GN   Name=ELAC1; Synonyms=D29;
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042779; P:tRNA 3'-trailer cleavage; IEA:InterPro.
//
ID   RNZ2_HUMAN              Reviewed;         826 AA.
AC   Q9BQ52; B4DPL9; Q6IA94; Q9HAS8; Q9HAS9; Q9NVT1;
DE   RecName: Full=Zinc phosphodiesterase ELAC protein 2;
DE            EC=3.1.26.11;
DE   AltName: Full=ElaC homolog protein 2;
DE   AltName: Full=Heredity prostate cancer protein 2;
DE   AltName: Full=Ribonuclease Z 2;
DE            Short=RNase Z 2;
DE   AltName: Full=tRNA 3 endonuclease 2;
DE   AltName: Full=tRNase Z 2;
DE   Flags: Precursor;
GN   Name=ELAC2; Synonyms=HPC2;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0072684; P:mitochondrial tRNA 3'-trailer cleavage, endonucleolytic; IMP:UniProtKB.
//
ID   RO52_HUMAN              Reviewed;         475 AA.
AC   P19474; Q5XPV5; Q96RF8;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM21;
DE            EC=6.3.2.-;
DE   AltName: Full=52 kDa Ro protein;
DE   AltName: Full=52 kDa ribonucleoprotein autoantigen Ro/SS-A;
DE   AltName: Full=RING finger protein 81;
DE   AltName: Full=Ro(SS-A);
DE   AltName: Full=Sjoegren syndrome type A antigen;
DE            Short=SS-A;
DE   AltName: Full=Tripartite motif-containing protein 21;
GN   Name=TRIM21; Synonyms=RNF81, RO52, SSA1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IMP:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
//
ID   RO60_HUMAN              Reviewed;         538 AA.
AC   P10155; B2RBB9; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787;
AC   Q9H1W6;
DE   RecName: Full=60 kDa SS-A/Ro ribonucleoprotein;
DE            Short=60 kDa Ro protein;
DE            Short=60 kDa ribonucleoprotein Ro;
DE            Short=RoRNP;
DE   AltName: Full=Ro 60 kDa autoantigen;
DE   AltName: Full=Sjoegren syndrome antigen A2;
DE   AltName: Full=Sjoegren syndrome type A antigen;
DE            Short=SS-A;
DE   AltName: Full=TROVE domain family member 2;
GN   Name=TROVE2; Synonyms=RO60, SSA2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:ProtInc.
//
ID   ROA0_HUMAN              Reviewed;         305 AA.
AC   Q13151; Q6IB18;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A0;
DE            Short=hnRNP A0;
GN   Name=HNRNPA0; Synonyms=HNRPA0;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   ROA1_HUMAN              Reviewed;         372 AA.
AC   P09651; A8K4Z8; Q3MIB7; Q6PJZ7;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A1;
DE            Short=hnRNP A1;
DE   AltName: Full=Helix-destabilizing protein;
DE   AltName: Full=Single-strand RNA-binding protein;
DE   AltName: Full=hnRNP core protein A1;
DE   Contains:
DE     RecName: Full=Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;
GN   Name=HNRNPA1; Synonyms=HNRPA1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:HGNC.
DR   GO; GO:0003727; F:single-stranded RNA binding; IC:HGNC.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0051168; P:nuclear export; IDA:HGNC.
DR   GO; GO:0051170; P:nuclear import; IDA:HGNC.
DR   GO; GO:0006405; P:RNA export from nucleus; IC:HGNC.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ROA2_HUMAN              Reviewed;         353 AA.
AC   P22626; A8K064; P22627; Q9UC98; Q9UDJ2;
DE   RecName: Full=Heterogeneous nuclear ribonucleoproteins A2/B1;
DE            Short=hnRNP A2/B1;
GN   Name=HNRNPA2B1; Synonyms=HNRPA2B1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0097157; F:pre-mRNA intronic binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0003723; F:RNA binding; IDA:HGNC.
DR   GO; GO:0043047; F:single-stranded telomeric DNA binding; IDA:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; IDA:HGNC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0050658; P:RNA transport; IDA:HGNC.
//
ID   ROA3_HUMAN              Reviewed;         378 AA.
AC   P51991; D3DPF4; Q53RW7; Q6URK5;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A3;
DE            Short=hnRNP A3;
GN   Name=HNRNPA3; Synonyms=HNRPA3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   ROAA_HUMAN              Reviewed;         332 AA.
AC   Q99729; B3KNN5; D3DWP7; Q04150; Q8N7U3; Q9BQ99;
DE   RecName: Full=Heterogeneous nuclear ribonucleoprotein A/B;
DE            Short=hnRNP A/B;
DE   AltName: Full=APOBEC1-binding protein 1;
DE            Short=ABBP-1;
GN   Name=HNRNPAB; Synonyms=ABBP1, HNRPAB;
DR   GO; GO:0003729; F:mRNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:HGNC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:HGNC.
//
ID   ROBO1_HUMAN             Reviewed;        1651 AA.
AC   Q9Y6N7; B2RXI1; D3DU36; E9PD49; Q1RMC7; Q7Z300; Q9BUS7;
DE   RecName: Full=Roundabout homolog 1;
DE   AltName: Full=Deleted in U twenty twenty;
DE   AltName: Full=H-Robo-1;
DE   Flags: Precursor;
GN   Name=ROBO1; Synonyms=DUTT1;
DR   GO; GO:0008046; F:axon guidance receptor activity; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0030275; F:LRR domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016199; P:axon midline choice point recognition; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0021836; P:chemorepulsion involved in postnatal olfactory bulb interneuron migration; IDA:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.
DR   GO; GO:0060763; P:mammary duct terminal end bud growth; IEA:Ensembl.
DR   GO; GO:0070100; P:negative regulation of chemokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0050925; P:negative regulation of negative chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IDA:UniProtKB.
DR   GO; GO:0035385; P:Roundabout signaling pathway; IMP:BHF-UCL.
//
ID   ROBO2_HUMAN             Reviewed;        1378 AA.
AC   Q9HCK4; O43608; Q19AB4; Q19AB5;
DE   RecName: Full=Roundabout homolog 2;
DE   Flags: Precursor;
GN   Name=ROBO2; Synonyms=KIAA1568;
DR   GO; GO:0008046; F:axon guidance receptor activity; ISS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0061364; P:apoptotic process involved in luteolysis; IEP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0016199; P:axon midline choice point recognition; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEP:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; IDA:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; ISS:UniProtKB.
DR   GO; GO:0050925; P:negative regulation of negative chemotaxis; IDA:UniProtKB.
DR   GO; GO:0051964; P:negative regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0021891; P:olfactory bulb interneuron development; ISS:UniProtKB.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IDA:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; ISS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; IMP:UniProtKB.
//
ID   ROBO3_HUMAN             Reviewed;        1386 AA.
AC   Q96MS0;
DE   RecName: Full=Roundabout homolog 3;
DE   AltName: Full=Roundabout-like protein 3;
DE   Flags: Precursor;
GN   Name=ROBO3;
DR   GO; GO:0007411; P:axon guidance; NAS:UniProtKB.
DR   GO; GO:0016199; P:axon midline choice point recognition; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
//
ID   ROBO4_HUMAN             Reviewed;        1007 AA.
AC   Q8WZ75; A8K154; Q14DU7; Q8TEG1; Q96JV6; Q9H718; Q9NWJ8;
DE   RecName: Full=Roundabout homolog 4;
DE   AltName: Full=Magic roundabout;
DE   Flags: Precursor;
GN   Name=ROBO4; ORFNames=UNQ421/PRO3674;
DR   GO; GO:0004872; F:receptor activity; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IGI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; NAS:UniProtKB.
//
ID   ROCK1_HUMAN             Reviewed;        1354 AA.
AC   Q13464; B0YJ91; Q2KHM4; Q59GZ4;
DE   RecName: Full=Rho-associated protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-35;
DE   AltName: Full=Rho-associated, coiled-coil-containing protein kinase 1;
DE   AltName: Full=Rho-associated, coiled-coil-containing protein kinase I;
DE            Short=ROCK-I;
DE   AltName: Full=p160 ROCK-1;
DE            Short=p160ROCK;
GN   Name=ROCK1;
DR   GuidetoPHARMACOLOGY; 1503; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0003383; P:apical constriction; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0032060; P:bleb assembly; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; IDA:BHF-UCL.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IDA:BHF-UCL.
DR   GO; GO:0022614; P:membrane to membrane docking; IDA:BHF-UCL.
DR   GO; GO:0051451; P:myoblast migration; ISS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; TAS:UniProtKB.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; TAS:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; TAS:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
//
ID   ROCK2_HUMAN             Reviewed;        1388 AA.
AC   O75116; Q53QZ0; Q53SJ7; Q9UQN5;
DE   RecName: Full=Rho-associated protein kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=Rho kinase 2;
DE   AltName: Full=Rho-associated, coiled-coil-containing protein kinase 2;
DE   AltName: Full=Rho-associated, coiled-coil-containing protein kinase II;
DE            Short=ROCK-II;
DE   AltName: Full=p164 ROCK-2;
GN   Name=ROCK2; Synonyms=KIAA0619;
DR   GuidetoPHARMACOLOGY; 1504; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; NAS:ProtInc.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; NAS:ProtInc.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0010825; P:positive regulation of centrosome duplication; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; TAS:UniProtKB.
DR   GO; GO:2000145; P:regulation of cell motility; TAS:UniProtKB.
DR   GO; GO:2000114; P:regulation of establishment of cell polarity; TAS:UniProtKB.
DR   GO; GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; TAS:UniProtKB.
DR   GO; GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
//
ID   ROGDI_HUMAN             Reviewed;         287 AA.
AC   Q9GZN7; Q6IA00;
DE   RecName: Full=Protein rogdi homolog;
GN   Name=ROGDI;
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   ROM1_HUMAN              Reviewed;         351 AA.
AC   Q03395; B2R978;
DE   RecName: Full=Rod outer segment membrane protein 1;
DE            Short=ROSP1;
DE   AltName: Full=Tetraspanin-23;
DE            Short=Tspan-23;
GN   Name=ROM1; Synonyms=TSPAN23;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   ROMO1_HUMAN             Reviewed;          79 AA.
AC   P60602; A7M872; E1P5R9; E9KL28; Q3MHD5; Q5QP16; Q9CQ98; Q9H1N2;
DE   RecName: Full=Reactive oxygen species modulator 1;
DE            Short=ROS modulator 1;
DE   AltName: Full=Epididymis tissue protein Li 175;
DE   AltName: Full=Glyrichin;
DE   AltName: Full=Mitochondrial targeting GxxxG motif protein;
DE            Short=MTGM;
DE   AltName: Full=Protein MGR2 homolog;
GN   Name=ROMO1; Synonyms=C20orf52;
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IMP:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0001302; P:replicative cell aging; IMP:UniProtKB.
//
ID   RON_HUMAN               Reviewed;        1400 AA.
AC   Q04912; B5A944; B5A945; B5A946; B5A947;
DE   RecName: Full=Macrophage-stimulating protein receptor;
DE            Short=MSP receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=CDw136;
DE   AltName: Full=Protein-tyrosine kinase 8;
DE   AltName: Full=p185-Ron;
DE   AltName: CD_antigen=CD136;
DE   Contains:
DE     RecName: Full=Macrophage-stimulating protein receptor alpha chain;
DE   Contains:
DE     RecName: Full=Macrophage-stimulating protein receptor beta chain;
DE   Flags: Precursor;
GN   Name=MST1R; Synonyms=PTK8, RON;
DR   GuidetoPHARMACOLOGY; 1816; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005011; F:macrophage colony-stimulating factor receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0038145; P:macrophage colony-stimulating factor signaling pathway; TAS:GOC.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
//
ID   ROP1A_HUMAN             Reviewed;         212 AA.
AC   Q9HAT0; D3DN99; Q9UF38;
DE   RecName: Full=Ropporin-1A;
DE   AltName: Full=Cancer/testis antigen 91;
DE            Short=CT91;
DE   AltName: Full=Rhophilin-associated protein 1A;
GN   Name=ROPN1; Synonyms=ROPN1A;
//
ID   ROP1B_HUMAN             Reviewed;         212 AA.
AC   Q9BZX4; D3DNA6; Q96BM7;
DE   RecName: Full=Ropporin-1B;
DE   AltName: Full=Rhophilin-associated protein 1B;
GN   Name=ROPN1B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
DR   GO; GO:0007340; P:acrosome reaction; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; NAS:UniProtKB.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; NAS:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; TAS:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   ROP1L_HUMAN             Reviewed;         230 AA.
AC   Q96C74; D3DTC9; Q9BZX0;
DE   RecName: Full=Ropporin-1-like protein;
DE            Short=ROPN1-like protein;
DE   AltName: Full=AKAP-associated sperm protein;
GN   Name=ROPN1L; Synonyms=ASP;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0003351; P:epithelial cilium movement; IC:BHF-UCL.
//
ID   ROR1_HUMAN              Reviewed;         937 AA.
AC   Q01973; Q5VVX6; Q66K77; Q92776;
DE   RecName: Full=Tyrosine-protein kinase transmembrane receptor ROR1;
DE            EC=2.7.10.1;
DE   AltName: Full=Neurotrophic tyrosine kinase, receptor-related 1;
DE   Flags: Precursor;
GN   Name=ROR1; Synonyms=NTRKR1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   ROR2_HUMAN              Reviewed;         943 AA.
AC   Q01974; Q59GF5; Q5SPI5; Q9HAY7; Q9HB61;
DE   RecName: Full=Tyrosine-protein kinase transmembrane receptor ROR2;
DE            EC=2.7.10.1;
DE   AltName: Full=Neurotrophic tyrosine kinase, receptor-related 2;
DE   Flags: Precursor;
GN   Name=ROR2; Synonyms=NTRKR2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0030538; P:embryonic genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
DR   GO; GO:0007223; P:Wnt signaling pathway, calcium modulating pathway; IEA:Ensembl.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   RORA_HUMAN              Reviewed;         523 AA.
AC   P35398; P35397; P35399; P45445; Q495X4; Q96H83;
DE   RecName: Full=Nuclear receptor ROR-alpha;
DE   AltName: Full=Nuclear receptor RZR-alpha;
DE   AltName: Full=Nuclear receptor subfamily 1 group F member 1;
DE   AltName: Full=RAR-related orphan receptor A;
DE   AltName: Full=Retinoid-related orphan receptor-alpha;
GN   Name=RORA; Synonyms=NR1F1, RZRA;
DR   GuidetoPHARMACOLOGY; 598; -.
DR   GO; GO:0098531; F:direct ligand regulated sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.
DR   GO; GO:0008142; F:oxysterol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0001223; F:transcription coactivator binding; IPI:UniProtKB.
DR   GO; GO:0001222; F:transcription corepressor binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IMP:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:UniProtKB.
DR   GO; GO:0036315; P:cellular response to sterol; IDA:UniProtKB.
DR   GO; GO:0021930; P:cerebellar granule cell precursor proliferation; ISS:UniProtKB.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0046068; P:cGMP metabolic process; IEA:Ensembl.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042692; P:muscle cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:UniProtKB.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IMP:UniProtKB.
DR   GO; GO:2000188; P:regulation of cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0043030; P:regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0019218; P:regulation of steroid metabolic process; ISS:UniProtKB.
DR   GO; GO:0060850; P:regulation of transcription involved in cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0072539; P:T-helper 17 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; IMP:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; ISS:UniProtKB.
//
ID   RORB_HUMAN              Reviewed;         470 AA.
AC   Q92753; Q8WX73;
DE   RecName: Full=Nuclear receptor ROR-beta;
DE   AltName: Full=Nuclear receptor RZR-beta;
DE   AltName: Full=Nuclear receptor subfamily 1 group F member 2;
DE   AltName: Full=Retinoid-related orphan receptor-beta;
GN   Name=RORB; Synonyms=NR1F2, RZRB;
DR   GuidetoPHARMACOLOGY; 599; -.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035881; P:amacrine cell differentiation; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0042462; P:eye photoreceptor cell development; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0046549; P:retinal cone cell development; ISS:UniProtKB.
DR   GO; GO:0046548; P:retinal rod cell development; ISS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RORG_HUMAN              Reviewed;         518 AA.
AC   P51449; Q5SZR9; Q8N5V7; Q8NCY8;
DE   RecName: Full=Nuclear receptor ROR-gamma;
DE   AltName: Full=Nuclear receptor RZR-gamma;
DE   AltName: Full=Nuclear receptor subfamily 1 group F member 3;
DE   AltName: Full=RAR-related orphan receptor C;
DE   AltName: Full=Retinoid-related orphan receptor-gamma;
GN   Name=RORC; Synonyms=NR1F3, RORG, RZRG;
DR   GuidetoPHARMACOLOGY; 600; -.
DR   GO; GO:0098531; F:direct ligand regulated sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008142; F:oxysterol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060612; P:adipose tissue development; ISS:UniProtKB.
DR   GO; GO:0036315; P:cellular response to sterol; IDA:UniProtKB.
DR   GO; GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0048537; P:mucosal-associated lymphoid tissue development; IEA:Ensembl.
DR   GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; ISS:UniProtKB.
DR   GO; GO:0048541; P:Peyer's patch development; ISS:UniProtKB.
DR   GO; GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0019218; P:regulation of steroid metabolic process; ISS:UniProtKB.
DR   GO; GO:0060850; P:regulation of transcription involved in cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0072539; P:T-helper 17 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042093; P:T-helper cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; ISS:UniProtKB.
//
ID   ROS1_HUMAN              Reviewed;        2347 AA.
AC   P08922; Q15368; Q5TDB5;
DE   RecName: Full=Proto-oncogene tyrosine-protein kinase ROS;
DE            EC=2.7.10.1;
DE   AltName: Full=Proto-oncogene c-Ros;
DE   AltName: Full=Proto-oncogene c-Ros-1;
DE   AltName: Full=Receptor tyrosine kinase c-ros oncogene 1;
DE   AltName: Full=c-Ros receptor tyrosine kinase;
DE   Flags: Precursor;
GN   Name=ROS1; Synonyms=MCF3, ROS;
DR   GuidetoPHARMACOLOGY; 1840; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030154; P:cell differentiation; ISS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0002066; P:columnar/cuboidal epithelial cell development; ISS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0010966; P:regulation of phosphate transport; IEA:Ensembl.
DR   GO; GO:0032006; P:regulation of TOR signaling; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro.
//
ID   RP1BL_HUMAN             Reviewed;         184 AA.
AC   A6NIZ1;
DE   RecName: Full=Ras-related protein Rap-1b-like protein;
DE   Flags: Precursor;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RP1L1_HUMAN             Reviewed;        2480 AA.
AC   Q8IWN7; Q86SQ1; Q8IWN8; Q8IWN9; Q8IWP0; Q8IWP1; Q8IWP2;
DE   RecName: Full=Retinitis pigmentosa 1-like 1 protein;
GN   Name=RP1L1;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0042461; P:photoreceptor cell development; ISS:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RP1_HUMAN               Reviewed;        2156 AA.
AC   P56715;
DE   RecName: Full=Oxygen-regulated protein 1;
DE   AltName: Full=Retinitis pigmentosa 1 protein;
DE   AltName: Full=Retinitis pigmentosa RP1 protein;
GN   Name=RP1; Synonyms=ORP1;
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035082; P:axoneme assembly; ISS:UniProtKB.
DR   GO; GO:0071482; P:cellular response to light stimulus; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0042461; P:photoreceptor cell development; ISS:UniProtKB.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:UniProtKB.
DR   GO; GO:0035845; P:photoreceptor cell outer segment organization; ISS:UniProtKB.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:ProtInc.
DR   GO; GO:0046549; P:retinal cone cell development; ISS:UniProtKB.
DR   GO; GO:0046548; P:retinal rod cell development; ISS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RP25L_HUMAN             Reviewed;         163 AA.
AC   Q8N5L8; D3DRM5;
DE   RecName: Full=Ribonuclease P protein subunit p25-like protein;
DE            Short=RNase P protein subunit-like p25;
DE   AltName: Full=Rpp25-like protein;
GN   Name=RPP25L; Synonyms=C9orf23;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RP3A_HUMAN              Reviewed;         694 AA.
AC   Q9Y2J0; B7Z3C3; Q96AE0;
DE   RecName: Full=Rabphilin-3A;
DE   AltName: Full=Exophilin-1;
GN   Name=RPH3A; Synonyms=KIAA0985;
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   RP9_HUMAN               Reviewed;         221 AA.
AC   Q8TA86;
DE   RecName: Full=Retinitis pigmentosa 9 protein;
DE   AltName: Full=Pim-1-associated protein;
DE            Short=PAP-1;
GN   Name=RP9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
//
ID   RPA12_HUMAN             Reviewed;         126 AA.
AC   Q9P1U0;
DE   RecName: Full=DNA-directed RNA polymerase I subunit RPA12;
DE   AltName: Full=Zinc ribbon domain-containing protein 1;
GN   Name=ZNRD1; Synonyms=RPA12;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; IBA:RefGenome.
//
ID   RPA1_HUMAN              Reviewed;        1720 AA.
AC   O95602; B7Z7T0; D6W5M0; Q0VG05; Q9UEH0; Q9UFT9;
DE   RecName: Full=DNA-directed RNA polymerase I subunit RPA1;
DE            Short=RNA polymerase I subunit A1;
DE            EC=2.7.7.6;
DE   AltName: Full=A190;
DE   AltName: Full=DNA-directed RNA polymerase I largest subunit;
DE   AltName: Full=DNA-directed RNA polymerase I subunit A;
DE   AltName: Full=RNA polymerase I 194 kDa subunit;
DE            Short=RPA194;
GN   Name=POLR1A;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   RPA2_HUMAN              Reviewed;        1135 AA.
AC   Q9H9Y6; Q585T5; Q6ZRR2; Q9H9D3;
DE   RecName: Full=DNA-directed RNA polymerase I subunit RPA2;
DE            Short=RNA polymerase I subunit 2;
DE            EC=2.7.7.6;
DE   AltName: Full=DNA-directed RNA polymerase I 135 kDa polypeptide;
DE            Short=RPA135;
GN   Name=POLR1B;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0017126; P:nucleologenesis; IEA:Ensembl.
DR   GO; GO:0009303; P:rRNA transcription; IEA:Ensembl.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   RPA34_HUMAN             Reviewed;         510 AA.
AC   O15446; Q32N11; Q7Z5U2; Q9UPF6;
DE   RecName: Full=DNA-directed RNA polymerase I subunit RPA34;
DE   AltName: Full=A34.5;
DE   AltName: Full=Antisense to ERCC-1 protein;
DE            Short=ASE-1;
DE   AltName: Full=CD3-epsilon-associated protein;
DE            Short=CAST;
DE            Short=CD3E-associated protein;
DE   AltName: Full=RNA polymerase I-associated factor PAF49;
GN   Name=CD3EAP; Synonyms=ASE1, CAST, PAF49;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009303; P:rRNA transcription; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   RPA43_HUMAN             Reviewed;         338 AA.
AC   Q3B726; A0PJ45; B7Z724;
DE   RecName: Full=DNA-directed RNA polymerase I subunit RPA43;
DE   AltName: Full=Twist neighbor protein;
GN   Name=TWISTNB;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; IBA:GOC.
//
ID   RPA49_HUMAN             Reviewed;         481 AA.
AC   Q9GZS1; Q5VZT3; Q8NBA9; Q96L20;
DE   RecName: Full=DNA-directed RNA polymerase I subunit RPA49;
DE            Short=RNA polymerase I subunit A49;
DE   AltName: Full=DNA-directed RNA polymerase I subunit E;
DE   AltName: Full=RNA polymerase I-associated factor 1;
DE   AltName: Full=RNA polymerase I-associated factor 53;
GN   Name=POLR1E; Synonyms=PAF53, PRAF1;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009303; P:rRNA transcription; ISS:HGNC.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; IBA:GOC.
//
ID   RPAB1_HUMAN             Reviewed;         210 AA.
AC   P19388; B2R6L4; D6W5Y1; O43380; Q6PIH5; Q9BT06;
DE   RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1;
DE            Short=RNA polymerases I, II, and III subunit ABC1;
DE   AltName: Full=DNA-directed RNA polymerase II 23 kDa polypeptide;
DE   AltName: Full=DNA-directed RNA polymerase II subunit E;
DE   AltName: Full=RPB5 homolog;
DE   AltName: Full=XAP4;
GN   Name=POLR2E;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPAB2_HUMAN             Reviewed;         127 AA.
AC   P61218; P41584; Q6IAY3;
DE   RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2;
DE            Short=RNA polymerases I, II, and III subunit ABC2;
DE   AltName: Full=DNA-directed RNA polymerase II subunit F;
DE   AltName: Full=DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide;
DE   AltName: Full=RPABC14.4;
DE            Short=RPB14.4;
DE   AltName: Full=RPB6 homolog;
DE   AltName: Full=RPC15;
GN   Name=POLR2F; Synonyms=POLRF;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPAB3_HUMAN             Reviewed;         150 AA.
AC   P52434; P53802; Q969R0;
DE   RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC3;
DE            Short=RNA polymerases I, II, and III subunit ABC3;
DE   AltName: Full=DNA-directed RNA polymerase II subunit H;
DE   AltName: Full=DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide;
DE   AltName: Full=RPB17;
DE   AltName: Full=RPB8 homolog;
DE            Short=hRPB8;
GN   Name=POLR2H;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPAB5_HUMAN             Reviewed;          67 AA.
AC   P62875; P52436; Q6FHX3;
DE   RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC5;
DE            Short=RNA polymerases I, II, and III subunit ABC5;
DE   AltName: Full=DNA-directed RNA polymerase III subunit L;
DE   AltName: Full=RNA polymerase II 7.6 kDa subunit;
DE            Short=RPB7.6;
DE   AltName: Full=RPB10 homolog;
GN   Name=POLR2L;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IBA:RefGenome.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006356; P:regulation of transcription from RNA polymerase I promoter; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPAB4_HUMAN             Reviewed;          58 AA.
AC   P53803; Q6IBD4;
DE   RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC4;
DE            Short=RNA polymerases I, II, and III subunit ABC4;
DE   AltName: Full=ABC10-alpha;
DE   AltName: Full=DNA-directed RNA polymerase II subunit K;
DE   AltName: Full=RNA polymerase II 7.0 kDa subunit;
DE            Short=RPB7.0;
DE   AltName: Full=RPB10alpha;
GN   Name=POLR2K;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006356; P:regulation of transcription from RNA polymerase I promoter; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPAC1_HUMAN             Reviewed;         346 AA.
AC   O15160; O75395; Q5JTE3;
DE   RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC1;
DE            Short=DNA-directed RNA polymerase I subunit C;
DE            Short=RNA polymerases I and III subunit AC1;
DE   AltName: Full=AC40;
DE   AltName: Full=DNA-directed RNA polymerases I and III 40 kDa polypeptide;
DE            Short=RPA40;
DE   AltName: Full=RPA39;
DE   AltName: Full=RPC40;
GN   Name=POLR1C; Synonyms=POLR1E;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   RPAC2_HUMAN             Reviewed;         133 AA.
AC   Q9Y2S0; Q5TBX2; Q96BR3;
DE   RecName: Full=DNA-directed RNA polymerases I and III subunit RPAC2;
DE            Short=RNA polymerases I and III subunit AC2;
DE   AltName: Full=AC19;
DE   AltName: Full=DNA-directed RNA polymerase I subunit D;
DE   AltName: Full=RNA polymerase I 16 kDa subunit;
DE            Short=RPA16;
DE   AltName: Full=RPC16;
DE   AltName: Full=hRPA19;
GN   Name=POLR1D;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   RPAP1_HUMAN             Reviewed;        1393 AA.
AC   Q9BWH6; Q9H9I2; Q9NSQ5; Q9P2E4; Q9UFS7;
DE   RecName: Full=RNA polymerase II-associated protein 1;
GN   Name=RPAP1; Synonyms=KIAA1403;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
//
ID   RPAP2_HUMAN             Reviewed;         612 AA.
AC   Q8IXW5; C9JKB5; Q49AS7; Q9H8Y2;
DE   RecName: Full=Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2;
DE            EC=3.1.3.16;
DE   AltName: Full=RNA polymerase II-associated protein 2;
GN   Name=RPAP2; Synonyms=C1orf82;
DR   GO; GO:0008420; F:CTD phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070940; P:dephosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.
DR   GO; GO:0009301; P:snRNA transcription; IMP:UniProtKB.
//
ID   RPAP3_HUMAN             Reviewed;         665 AA.
AC   Q9H6T3; B4DRW9; Q6PHR5;
DE   RecName: Full=RNA polymerase II-associated protein 3;
GN   Name=RPAP3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RPB11_HUMAN             Reviewed;         117 AA.
AC   P52435; A5D6V8; O43375;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB11-a;
DE            Short=RNA polymerase II subunit B11-a;
DE            Short=RPB11a;
DE   AltName: Full=DNA-directed RNA polymerase II subunit J-1;
DE   AltName: Full=RNA polymerase II 13.3 kDa subunit;
GN   Name=POLR2J; Synonyms=POLR2J1;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0030275; F:LRR domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPB1B_HUMAN             Reviewed;         115 AA.
AC   Q9GZM3; F6W009; Q9H1A8;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB11-b1;
DE            Short=RNA polymerase II subunit B11-b1;
DE            Short=RPB11b1;
DE   AltName: Full=DNA-directed RNA polymerase II subunit J2;
GN   Name=POLR2J2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   RPB1C_HUMAN             Reviewed;         115 AA.
AC   Q9H1A7; A6NKA1;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB11-b2;
DE            Short=RNA polymerase II subunit B11-b2;
DE            Short=RPB11b2;
DE   AltName: Full=DNA-directed RNA polymerase II subunit J3;
GN   Name=POLR2J3;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   RPB1_HUMAN              Reviewed;        1970 AA.
AC   P24928; A6NN93; B9EH88;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB1;
DE            Short=RNA polymerase II subunit B1;
DE            EC=2.7.7.6;
DE   AltName: Full=DNA-directed RNA polymerase II subunit A;
DE   AltName: Full=DNA-directed RNA polymerase III largest subunit;
DE   AltName: Full=RNA-directed RNA polymerase II subunit RPB1;
DE            EC=2.7.7.48;
GN   Name=POLR2A; Synonyms=POLR2;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPB2_HUMAN              Reviewed;        1174 AA.
AC   P30876; A8K1A8; Q8IZ61;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB2;
DE            EC=2.7.7.6;
DE   AltName: Full=DNA-directed RNA polymerase II 140 kDa polypeptide;
DE   AltName: Full=DNA-directed RNA polymerase II subunit B;
DE   AltName: Full=RNA polymerase II subunit 2;
DE   AltName: Full=RNA polymerase II subunit B2;
GN   Name=POLR2B;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPB3_HUMAN              Reviewed;         275 AA.
AC   P19387; O15161;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB3;
DE            Short=RNA polymerase II subunit 3;
DE            Short=RNA polymerase II subunit B3;
DE   AltName: Full=DNA-directed RNA polymerase II 33 kDa polypeptide;
DE            Short=RPB33;
DE   AltName: Full=DNA-directed RNA polymerase II subunit C;
DE   AltName: Full=RPB31;
GN   Name=POLR2C; ORFNames=A-152E5.7;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPB4_HUMAN              Reviewed;         142 AA.
AC   O15514; Q52LT4;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB4;
DE            Short=RNA polymerase II subunit B4;
DE   AltName: Full=DNA-directed RNA polymerase II subunit D;
DE   AltName: Full=RNA polymerase II 16 kDa subunit;
DE            Short=RPB16;
GN   Name=POLR2D;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IMP:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0031369; F:translation initiation factor binding; IBA:RefGenome.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031990; P:mRNA export from nucleus in response to heat stress; IBA:RefGenome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IBA:RefGenome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IBA:RefGenome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0034402; P:recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; IBA:RefGenome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPB7_HUMAN              Reviewed;         172 AA.
AC   P62487; B2R5C0; P52433; Q2M1Z4;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB7;
DE            Short=RNA polymerase II subunit B7;
DE   AltName: Full=DNA-directed RNA polymerase II subunit G;
DE   AltName: Full=RNA polymerase II 19 kDa subunit;
DE            Short=RPB19;
GN   Name=POLR2G; Synonyms=RPB7;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003697; F:single-stranded DNA binding; IBA:RefGenome.
DR   GO; GO:0003727; F:single-stranded RNA binding; IBA:RefGenome.
DR   GO; GO:0031369; F:translation initiation factor binding; IBA:RefGenome.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0000291; P:nuclear-transcribed mRNA catabolic process, exonucleolytic; IBA:RefGenome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IBA:RefGenome.
DR   GO; GO:0045948; P:positive regulation of translational initiation; IBA:RefGenome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPB9_HUMAN              Reviewed;         125 AA.
AC   P36954; B2R5J2; Q6NW05;
DE   RecName: Full=DNA-directed RNA polymerase II subunit RPB9;
DE            Short=RNA polymerase II subunit B9;
DE   AltName: Full=DNA-directed RNA polymerase II subunit I;
DE   AltName: Full=RNA polymerase II 14.5 kDa subunit;
DE            Short=RPB14.5;
GN   Name=POLR2I;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001193; P:maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IBA:RefGenome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   RPC10_HUMAN             Reviewed;         108 AA.
AC   Q9Y2Y1; Q1W6H4; Q96S35;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC10;
DE            Short=RNA polymerase III subunit C10;
DE   AltName: Full=DNA-directed RNA polymerase III subunit K;
DE   AltName: Full=RNA polymerase III 12.5 kDa subunit;
DE            Short=RPC12.5;
DE   AltName: Full=RNA polymerase III subunit C11;
DE            Short=HsC11p;
DE            Short=RPC11;
DE            Short=hRPC11;
GN   Name=POLR3K; Synonyms=RPC11; ORFNames=My010;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; IBA:RefGenome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC1_HUMAN              Reviewed;        1390 AA.
AC   O14802; Q8IW34; Q8TCW5;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC1;
DE            Short=RNA polymerase III subunit C1;
DE            EC=2.7.7.6;
DE   AltName: Full=DNA-directed RNA polymerase III largest subunit;
DE   AltName: Full=DNA-directed RNA polymerase III subunit A;
DE   AltName: Full=RNA polymerase III 155 kDa subunit;
DE            Short=RPC155;
DE   AltName: Full=RNA polymerase III subunit C160;
GN   Name=POLR3A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   RPC2_HUMAN              Reviewed;        1133 AA.
AC   Q9NW08; A8K6H0; B3KV73; F5H1E6; Q9NW59;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC2;
DE            Short=RNA polymerase III subunit C2;
DE            EC=2.7.7.6;
DE   AltName: Full=C128;
DE   AltName: Full=DNA-directed RNA polymerase III 127.6 kDa polypeptide;
DE   AltName: Full=DNA-directed RNA polymerase III subunit B;
GN   Name=POLR3B;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC3_HUMAN              Reviewed;         534 AA.
AC   Q9BUI4; O15317; Q9Y3R6;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC3;
DE            Short=RNA polymerase III subunit C3;
DE   AltName: Full=DNA-directed RNA polymerase III subunit C;
DE   AltName: Full=RNA polymerase III 62 kDa subunit;
DE            Short=RPC62;
GN   Name=POLR3C;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC4_HUMAN              Reviewed;         398 AA.
AC   P05423; Q6FI28; Q9BPV7; Q9BPZ1; Q9BXB3;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC4;
DE            Short=RNA polymerase III subunit C4;
DE   AltName: Full=DNA-directed RNA polymerase III subunit D;
DE   AltName: Full=Protein BN51;
DE   AltName: Full=RNA polymerase III 47 kDa subunit;
DE   AltName: Full=RPC53 homolog;
GN   Name=POLR3D; Synonyms=BN51, BN51T;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC5_HUMAN              Reviewed;         708 AA.
AC   Q9NVU0; B4DL24; B4DUP6; H3BT11; Q9BWF7; Q9H8W8; Q9H907; Q9P276;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC5;
DE            Short=RNA polymerase III subunit C5;
DE   AltName: Full=DNA-directed RNA polymerase III 80 kDa polypeptide;
GN   Name=POLR3E; Synonyms=KIAA1452;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC6_HUMAN              Reviewed;         316 AA.
AC   Q9H1D9; A8K4C7; O15319;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC6;
DE            Short=RNA polymerase III subunit C6;
DE   AltName: Full=DNA-directed RNA polymerase III subunit F;
DE   AltName: Full=RNA polymerase III 39 kDa subunit;
DE            Short=RPC39;
GN   Name=POLR3F;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; NAS:UniProtKB.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC7_HUMAN              Reviewed;         223 AA.
AC   O15318; A8MTH0;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC7;
DE            Short=RNA polymerase III subunit C7;
DE   AltName: Full=DNA-directed RNA polymerase III subunit G;
DE   AltName: Full=RNA polymerase III 32 kDa subunit;
DE            Short=RPC32;
GN   Name=POLR3G;
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IMP:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC8_HUMAN              Reviewed;         204 AA.
AC   Q9Y535; B0QYH9; Q5M7Y8; Q96AE3; Q9BY95;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC8;
DE            Short=RNA polymerase III subunit C8;
DE   AltName: Full=DNA-directed RNA polymerase III subunit H;
DE   AltName: Full=RNA polymerase III subunit 22.9 kDa subunit;
DE            Short=RPC22.9;
GN   Name=POLR3H; Synonyms=KIAA1665, RPC8;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IDA:UniProtKB.
DR   GO; GO:0006384; P:transcription initiation from RNA polymerase III promoter; IBA:RefGenome.
//
ID   RPC7L_HUMAN             Reviewed;         218 AA.
AC   Q9BT43; B1MVG5;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC7-like;
DE            Short=RNA polymerase III subunit C7-like;
DE   AltName: Full=DNA-directed RNA polymerase III subunit G-like;
GN   Name=POLR3GL;
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0006386; P:termination of RNA polymerase III transcription; TAS:Reactome.
DR   GO; GO:0006385; P:transcription elongation from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   RPC9_HUMAN              Reviewed;         148 AA.
AC   O75575; A8MUZ4; A8MW23; B2R4H4; B4E198; Q3KRA3; Q5HYF1; Q8IXL4;
DE   RecName: Full=DNA-directed RNA polymerase III subunit RPC9;
DE            Short=RNA polymerase III subunit C9;
DE   AltName: Full=Calcitonin gene-related peptide-receptor component protein;
DE            Short=CGRP-RCP;
DE            Short=CGRP-receptor component protein;
DE            Short=CGRPRCP;
DE            Short=HsC17;
GN   Name=CRCP;
DR   GO; GO:0001635; F:calcitonin gene-related polypeptide receptor activity; IEA:Ensembl.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:Ensembl.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IDA:UniProtKB.
//
ID   RPE65_HUMAN             Reviewed;         533 AA.
AC   Q16518; A8K1L0; Q5T9U3;
DE   RecName: Full=Retinoid isomerohydrolase;
DE            EC=3.1.1.64;
DE   AltName: Full=All-trans-retinyl-palmitate hydrolase;
DE   AltName: Full=Retinal pigment epithelium-specific 65 kDa protein;
DE   AltName: Full=Retinol isomerase;
GN   Name=RPE65;
DR   GO; GO:0052885; F:all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity; IEA:UniProtKB-EC.
DR   GO; GO:0052884; F:all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004744; F:retinal isomerase activity; IEA:Ensembl.
DR   GO; GO:0071257; P:cellular response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProt.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0007468; P:regulation of rhodopsin gene expression; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IMP:UniProt.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0042574; P:retinal metabolic process; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
DR   GO; GO:0006776; P:vitamin A metabolic process; TAS:ProtInc.
//
ID   RPEL1_HUMAN             Reviewed;         228 AA.
AC   Q2QD12;
DE   RecName: Full=Ribulose-phosphate 3-epimerase-like protein 1;
DE            EC=5.1.3.1;
DE   AltName: Full=Ribulose-5-phosphate-3-epimerase-like protein 1;
GN   Name=RPEL1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004750; F:ribulose-phosphate 3-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
//
ID   RPE_HUMAN               Reviewed;         228 AA.
AC   Q96AT9; A8K4S0; O43767; Q53TV9; Q8N215; Q96N34; Q9BSB5;
DE   RecName: Full=Ribulose-phosphate 3-epimerase;
DE            EC=5.1.3.1;
DE   AltName: Full=Ribulose-5-phosphate-3-epimerase;
GN   Name=RPE; ORFNames=HUSSY-17;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004750; F:ribulose-phosphate 3-epimerase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RPF1_HUMAN              Reviewed;         349 AA.
AC   Q9H9Y2; Q5VSK7; Q6AHX1; Q8WXZ8;
DE   RecName: Full=Ribosome production factor 1;
DE   AltName: Full=Brix domain-containing protein 5;
DE   AltName: Full=Ribosome biogenesis protein RPF1;
GN   Name=RPF1; Synonyms=BXDC5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   RPF2_HUMAN              Reviewed;         306 AA.
AC   Q9H7B2; Q5VXN1; Q8N4A1;
DE   RecName: Full=Ribosome production factor 2 homolog;
DE   AltName: Full=Brix domain-containing protein 1;
DE   AltName: Full=Ribosome biogenesis protein RPF2 homolog;
GN   Name=RPF2; Synonyms=BXDC1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RPGF1_HUMAN             Reviewed;        1077 AA.
AC   Q13905; Q5JUE4; Q8IV73;
DE   RecName: Full=Rap guanine nucleotide exchange factor 1;
DE   AltName: Full=CRK SH3-binding GNRP;
DE   AltName: Full=Guanine nucleotide-releasing factor 2;
DE   AltName: Full=Protein C3G;
GN   Name=RAPGEF1; Synonyms=GRF2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; TAS:Reactome.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProtKB.
DR   GO; GO:0038180; P:nerve growth factor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; IMP:UniProtKB.
DR   GO; GO:1901888; P:regulation of cell junction assembly; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   RPGF2_HUMAN             Reviewed;        1499 AA.
AC   Q9Y4G8; D3DP27;
DE   RecName: Full=Rap guanine nucleotide exchange factor 2;
DE   AltName: Full=Cyclic nucleotide ras GEF;
DE            Short=CNrasGEF;
DE   AltName: Full=Neural RAP guanine nucleotide exchange protein;
DE            Short=nRap GEP;
DE   AltName: Full=PDZ domain-containing guanine nucleotide exchange factor 1;
DE            Short=PDZ-GEF1;
DE   AltName: Full=RA-GEF-1;
DE   AltName: Full=Ras/Rap1-associating GEF-1;
GN   Name=RAPGEF2; Synonyms=KIAA0313, NRAPGEP, PDZGEF1;
DR   GO; GO:0031697; F:beta-1 adrenergic receptor binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0030552; F:cAMP binding; IDA:UniProtKB.
DR   GO; GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046582; F:Rap GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IDA:UniProtKB.
DR   GO; GO:0071880; P:adenylate cyclase-activating adrenergic receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; ISS:UniProtKB.
DR   GO; GO:0031547; P:brain-derived neurotrophic factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0071321; P:cellular response to cGMP; IDA:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProtKB.
DR   GO; GO:0021884; P:forebrain neuron development; ISS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050774; P:negative regulation of dendrite morphogenesis; IDA:UniProtKB.
DR   GO; GO:0048022; P:negative regulation of melanin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0038180; P:nerve growth factor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000481; P:positive regulation of cAMP-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0043950; P:positive regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:2000670; P:positive regulation of dendritic cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:2001224; P:positive regulation of neuron migration; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0032092; P:positive regulation of protein binding; ISS:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; IMP:UniProtKB.
DR   GO; GO:1901888; P:regulation of cell junction assembly; IMP:UniProtKB.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:UniProtKB.
DR   GO; GO:0021591; P:ventricular system development; ISS:UniProtKB.
//
ID   RPGF3_HUMAN             Reviewed;         923 AA.
AC   O95398; A8K2G5; E7EQC8; O95634; Q8WVN0;
DE   RecName: Full=Rap guanine nucleotide exchange factor 3;
DE   AltName: Full=Exchange factor directly activated by cAMP 1;
DE   AltName: Full=Exchange protein directly activated by cAMP 1;
DE            Short=EPAC 1;
DE   AltName: Full=Rap1 guanine-nucleotide-exchange factor directly activated by cAMP;
DE   AltName: Full=cAMP-regulated guanine nucleotide exchange factor I;
DE            Short=cAMP-GEFI;
GN   Name=RAPGEF3; Synonyms=CGEF1, EPAC, EPAC1;
DR   GO; GO:0030552; F:cAMP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0019933; P:cAMP-mediated signaling; NAS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0030822; P:positive regulation of cAMP catabolic process; NAS:BHF-UCL.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; IMP:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.
DR   GO; GO:0032486; P:Rap protein signal transduction; IMP:UniProtKB.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RPGF4_HUMAN             Reviewed;        1011 AA.
AC   Q8WZA2; B2R7R3; B7Z283; B7Z3T6; B7Z912; O95636; Q8IXK6; Q8TAA4;
DE   RecName: Full=Rap guanine nucleotide exchange factor 4;
DE   AltName: Full=Exchange factor directly activated by cAMP 2;
DE   AltName: Full=Exchange protein directly activated by cAMP 2;
DE            Short=EPAC 2;
DE   AltName: Full=cAMP-regulated guanine nucleotide exchange factor II;
DE            Short=cAMP-GEFII;
GN   Name=RAPGEF4; Synonyms=CGEF2, EPAC2;
DR   GuidetoPHARMACOLOGY; 1293; -.
DR   GO; GO:0030552; F:cAMP binding; IEA:Ensembl.
DR   GO; GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017016; F:Ras GTPase binding; ISS:UniProtKB.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IEA:Ensembl.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; ISS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RPGF5_HUMAN             Reviewed;         580 AA.
AC   Q92565; A4D140; Q8IXU5;
DE   RecName: Full=Rap guanine nucleotide exchange factor 5;
DE   AltName: Full=Guanine nucleotide exchange factor for Rap1;
DE   AltName: Full=M-Ras-regulated Rap GEF;
DE            Short=MR-GEF;
DE   AltName: Full=Related to Epac;
DE            Short=Repac;
GN   Name=RAPGEF5; Synonyms=GFR, KIAA0277, MRGEF;
DR   GO; GO:0030742; F:GTP-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0017034; F:Rap guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0032317; P:regulation of Rap GTPase activity; IDA:GOC.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
//
ID   RPGF6_HUMAN             Reviewed;        1601 AA.
AC   Q8TEU7; A3KN82; A5PLL6; B7ZML2; E9PDV7; Q8NI21; Q8TEU6; Q96PC1;
DE   RecName: Full=Rap guanine nucleotide exchange factor 6;
DE   AltName: Full=PDZ domain-containing guanine nucleotide exchange factor 2;
DE            Short=PDZ-GEF2;
DE   AltName: Full=RA-GEF-2;
GN   Name=RAPGEF6; Synonyms=PDZGEF2;
DR   GO; GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017016; F:Ras GTPase binding; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; NAS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RPGFL_HUMAN             Reviewed;         662 AA.
AC   Q9UHV5;
DE   RecName: Full=Rap guanine nucleotide exchange factor-like 1;
DE   AltName: Full=Link guanine nucleotide exchange factor II;
DE            Short=Link GEFII;
GN   Name=RAPGEFL1;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RPGP1_HUMAN             Reviewed;         663 AA.
AC   P47736; J3QSS6; O75062; Q5T3S9; Q5T3T4; Q7Z5S8; Q9UQ51;
DE   RecName: Full=Rap1 GTPase-activating protein 1;
DE            Short=Rap1GAP;
DE            Short=Rap1GAP1;
GN   Name=RAP1GAP; Synonyms=KIAA0474, RAP1GA1;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0046582; F:Rap GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; NAS:GOC.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   RPGP2_HUMAN             Reviewed;         730 AA.
AC   Q684P5; B2RTY5; Q684P4; Q6AI00; Q6ZVF0; Q9UPW2;
DE   RecName: Full=Rap1 GTPase-activating protein 2;
DE            Short=Rap1GAP2;
DE   AltName: Full=GTPase-activating Rap/Ran-GAP domain-like protein 4;
GN   Name=RAP1GAP2; Synonyms=GARNL4, KIAA1039, RAP1GA2;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RPGR1_HUMAN             Reviewed;        1286 AA.
AC   Q96KN7; Q7Z2W6; Q8IXV5; Q96QA8; Q9HB94; Q9HB95; Q9HBK6; Q9NR40;
DE   RecName: Full=X-linked retinitis pigmentosa GTPase regulator-interacting protein 1;
DE            Short=RPGR-interacting protein 1;
GN   Name=RPGRIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   RPGR_HUMAN              Reviewed;        1020 AA.
AC   Q92834; B1ARN3; E9PE28; O00702; O00737; Q3KN84; Q8N5T6; Q93039;
AC   Q9HD29; Q9UMR1;
DE   RecName: Full=X-linked retinitis pigmentosa GTPase regulator;
DE   Flags: Precursor;
GN   Name=RPGR; Synonyms=RP3, XLRP3;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0042462; P:eye photoreceptor cell development; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0042073; P:intraciliary transport; ISS:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   RPH3L_HUMAN             Reviewed;         315 AA.
AC   Q9UNE2; D3DTG7; Q9BSB3;
DE   RecName: Full=Rab effector Noc2;
DE   AltName: Full=No C2 domains protein;
DE   AltName: Full=Rabphilin-3A-like protein;
GN   Name=RPH3AL; Synonyms=NOC2;
DR   GO; GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0045744; P:negative regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0017158; P:regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   RPIA_HUMAN              Reviewed;         311 AA.
AC   P49247; Q541P9; Q96BJ6;
DE   RecName: Full=Ribose-5-phosphate isomerase;
DE            EC=5.3.1.6;
DE   AltName: Full=Phosphoriboisomerase;
GN   Name=RPIA; Synonyms=RPI;
DR   GO; GO:0048029; F:monosaccharide binding; IEA:Ensembl.
DR   GO; GO:0004751; F:ribose-5-phosphate isomerase activity; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006098; P:pentose-phosphate shunt; TAS:Reactome.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:Ensembl.
DR   GO; GO:0019693; P:ribose phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   RPKL1_HUMAN             Reviewed;         549 AA.
AC   Q9Y6S9; A6NGM9; Q69YT9; Q6ZMQ6; Q96NR9; Q9BSU9;
DE   RecName: Full=Ribosomal protein S6 kinase-like 1;
DE            EC=2.7.11.1;
GN   Name=RPS6KL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   RPN1_HUMAN              Reviewed;         607 AA.
AC   P04843; B2R5Z0; D3DNB6; Q68DT1;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1;
DE            EC=2.4.99.18;
DE   AltName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit;
DE   AltName: Full=Ribophorin I;
DE            Short=RPN-I;
DE   AltName: Full=Ribophorin-1;
DE   Flags: Precursor;
GN   Name=RPN1;
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProt.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   RPN2_HUMAN              Reviewed;         631 AA.
AC   P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2;
DE            EC=2.4.99.18;
DE   AltName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit;
DE   AltName: Full=RIBIIR;
DE   AltName: Full=Ribophorin II;
DE            Short=RPN-II;
DE   AltName: Full=Ribophorin-2;
DE   Flags: Precursor;
GN   Name=RPN2;
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; NAS:HGNC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   RPOM_HUMAN              Reviewed;        1230 AA.
AC   O00411; O60370;
DE   RecName: Full=DNA-directed RNA polymerase, mitochondrial;
DE            Short=MtRPOL;
DE            EC=2.7.7.6;
DE   Flags: Precursor;
GN   Name=POLRMT;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IDA:UniProtKB.
DR   GO; GO:0006391; P:transcription initiation from mitochondrial promoter; TAS:Reactome.
//
ID   RPP14_HUMAN             Reviewed;         124 AA.
AC   O95059; Q53X97;
DE   RecName: Full=Ribonuclease P protein subunit p14;
DE            EC=3.1.26.5;
GN   Name=RPP14;
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   RPP21_HUMAN             Reviewed;         154 AA.
AC   Q9H633; A2AAZ8; B0S834; B0S835; Q5JPL9; Q5JPM1; Q5STF8; Q5STF9;
AC   Q5STG2; Q5SU41; Q5SU42; Q86Y49; Q86Y50; Q86Y51; Q96F16;
DE   RecName: Full=Ribonuclease P protein subunit p21;
DE            Short=RNaseP protein p21;
DE            EC=3.1.26.5;
DE   AltName: Full=Ribonuclease P/MRP 21 kDa subunit;
DE   AltName: Full=Ribonucleoprotein V;
GN   Name=RPP21; Synonyms=C6orf135, CAT60;
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0042493; P:response to drug; IEP:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   RPP25_HUMAN             Reviewed;         199 AA.
AC   Q9BUL9; D3DW70; Q9NX88;
DE   RecName: Full=Ribonuclease P protein subunit p25;
DE            Short=RNase P protein subunit p25;
DE            EC=3.1.26.5;
GN   Name=RPP25;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-EC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   RPP29_HUMAN             Reviewed;         220 AA.
AC   O95707; Q5XKL7; Q6FHW9; Q9UQQ3;
DE   RecName: Full=Ribonuclease P protein subunit p29;
DE            Short=hPOP4;
DE            EC=3.1.26.5;
GN   Name=POP4; Synonyms=RPP29;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004526; F:ribonuclease P activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006379; P:mRNA cleavage; IEA:InterPro.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
DR   GO; GO:0008033; P:tRNA processing; TAS:ProtInc.
//
ID   RPP30_HUMAN             Reviewed;         268 AA.
AC   P78346; B2R799; E9PB02;
DE   RecName: Full=Ribonuclease P protein subunit p30;
DE            Short=RNaseP protein p30;
DE            EC=3.1.26.5;
DE   AltName: Full=RNase P subunit 2;
GN   Name=RPP30; Synonyms=RNASEP2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004526; F:ribonuclease P activity; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   RPP38_HUMAN             Reviewed;         283 AA.
AC   P78345; B3KPY0; D3DRT8; Q53F71; Q8NHS8;
DE   RecName: Full=Ribonuclease P protein subunit p38;
DE            Short=RNaseP protein p38;
DE            EC=3.1.26.5;
GN   Name=RPP38;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004526; F:ribonuclease P activity; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   RPP40_HUMAN             Reviewed;         363 AA.
AC   O75818; Q5VX97; Q8WVK8;
DE   RecName: Full=Ribonuclease P protein subunit p40;
DE            Short=RNaseP protein p40;
DE            EC=3.1.26.5;
DE   AltName: Full=RNase P subunit 1;
GN   Name=RPP40; Synonyms=RNASEP1;
DR   GO; GO:0004526; F:ribonuclease P activity; TAS:ProtInc.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; TAS:GOC.
DR   GO; GO:0090502; P:RNA phosphodiester bond hydrolysis, endonucleolytic; TAS:GOC.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   RPR1A_HUMAN             Reviewed;         312 AA.
AC   Q96P16; A8KA42; B2RBA3; Q7Z5G8; Q96FY9; Q9NVL4;
DE   RecName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1A;
DE   AltName: Full=Cyclin-dependent kinase inhibitor 2B-related protein;
DE   AltName: Full=p15INK4B-related protein;
GN   Name=RPRD1A; Synonyms=P15RS;
DR   GO; GO:0070940; P:dephosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.
//
ID   RPR1B_HUMAN             Reviewed;         326 AA.
AC   Q9NQG5; Q1WDE7; Q6PKF4;
DE   RecName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B;
DE   AltName: Full=Cell cycle-related and expression-elevated protein in tumor;
GN   Name=RPRD1B; Synonyms=C20orf77, CREPT;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0070940; P:dephosphorylation of RNA polymerase II C-terminal domain; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010564; P:regulation of cell cycle process; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RPRD2_HUMAN             Reviewed;        1461 AA.
AC   Q5VT52; A8K6N8; B3KPT1; B4E2Q6; O75048; Q5VT51; Q5VT53; Q6MZL4;
AC   Q86XD2; Q9P0D7;
DE   RecName: Full=Regulation of nuclear pre-mRNA domain-containing protein 2;
GN   Name=RPRD2; Synonyms=KIAA0460; ORFNames=HSPC099;
//
ID   RPRML_HUMAN             Reviewed;         120 AA.
AC   Q8N4K4;
DE   RecName: Full=Reprimo-like protein;
GN   Name=RPRML;
//
ID   RPRM_HUMAN              Reviewed;         109 AA.
AC   Q9NS64; B2R4V1;
DE   RecName: Full=Protein reprimo;
GN   Name=RPRM;
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IEA:Ensembl.
//
ID   RPTN_HUMAN              Reviewed;         784 AA.
AC   Q6XPR3; B7ZBZ3;
DE   RecName: Full=Repetin;
GN   Name=RPTN;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   RPTOR_HUMAN             Reviewed;        1335 AA.
AC   Q8N122; B2RN36; C6KEF2; F5H7J5; Q8N4V9; Q8TB32; Q9P2P3;
DE   RecName: Full=Regulatory-associated protein of mTOR;
DE            Short=Raptor;
DE   AltName: Full=p150 target of rapamycin (TOR)-scaffold protein;
GN   Name=RPTOR; Synonyms=KIAA1303, RAPTOR;
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.
DR   GO; GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0016049; P:cell growth; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0031669; P:cellular response to nutrient levels; IMP:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IDA:UniProtKB.
DR   GO; GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.
DR   GO; GO:0008361; P:regulation of cell size; IMP:UniProtKB.
DR   GO; GO:0031929; P:TOR signaling; IDA:UniProtKB.
//
ID   RRAGB_HUMAN             Reviewed;         374 AA.
AC   Q5VZM2; A8K042; Q15348; Q8N3T0;
DE   RecName: Full=Ras-related GTP-binding protein B;
DE            Short=Rag B;
DE            Short=RagB;
GN   Name=RRAGB;
DR   GO; GO:0005525; F:GTP binding; IDA:HGNC.
DR   GO; GO:0032561; F:guanyl ribonucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; IMP:UniProtKB.
//
ID   RRAGA_HUMAN             Reviewed;         313 AA.
AC   Q7L523; B2R7L1; O00290; Q15347;
DE   RecName: Full=Ras-related GTP-binding protein A;
DE            Short=Rag A;
DE            Short=RagA;
DE   AltName: Full=Adenovirus E3 14.7 kDa-interacting protein 1;
DE   AltName: Full=FIP-1;
GN   Name=RRAGA;
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; IMP:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; IDA:UniProtKB.
DR   GO; GO:0045919; P:positive regulation of cytolysis; IDA:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; NAS:UniProtKB.
//
ID   RRAGC_HUMAN             Reviewed;         399 AA.
AC   Q9HB90; Q9H202; Q9H8Q8;
DE   RecName: Full=Ras-related GTP-binding protein C;
DE            Short=Rag C;
DE            Short=RagC;
DE   AltName: Full=GTPase-interacting protein 2;
DE   AltName: Full=TIB929;
GN   Name=RRAGC;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:HGNC.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; ISS:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0008380; P:RNA splicing; NAS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   RRAGD_HUMAN             Reviewed;         400 AA.
AC   Q9NQL2; A8K184; Q7L8F9; Q9NPG0;
DE   RecName: Full=Ras-related GTP-binding protein D;
DE            Short=Rag D;
DE            Short=RagD;
GN   Name=RRAGD;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0034613; P:cellular protein localization; ISS:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; ISS:UniProtKB.
DR   GO; GO:0032008; P:positive regulation of TOR signaling; NAS:UniProtKB.
//
ID   RRAS2_HUMAN             Reviewed;         204 AA.
AC   P62070; B2R9Z3; B7Z6C4; B7Z7H6; P17082;
DE   RecName: Full=Ras-related protein R-Ras2;
DE   AltName: Full=Ras-like protein TC21;
DE   AltName: Full=Teratocarcinoma oncogene;
DE   Flags: Precursor;
GN   Name=RRAS2; Synonyms=TC21;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
//
ID   RRAS_HUMAN              Reviewed;         218 AA.
AC   P10301; Q6FH12;
DE   RecName: Full=Ras-related protein R-Ras;
DE   AltName: Full=p23;
DE   Flags: Precursor;
GN   Name=RRAS;
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   RRBP1_HUMAN             Reviewed;        1410 AA.
AC   Q9P2E9; A2A2S6; A6NCN6; O75300; O75301; Q5W165; Q96SB2; Q9BWP1;
AC   Q9H476;
DE   RecName: Full=Ribosome-binding protein 1;
DE   AltName: Full=180 kDa ribosome receptor homolog;
DE            Short=RRp;
DE   AltName: Full=ES/130-related protein;
DE   AltName: Full=Ribosome receptor protein;
GN   Name=RRBP1; Synonyms=KIAA1398;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   RREB1_HUMAN             Reviewed;        1687 AA.
AC   Q92766; A2RRF5; E2GM80; E2GM81; O75567; O75568; Q5VYB2; Q6BEP5;
AC   Q6BEP6; Q6BEP8; Q86SU2; Q9Y474;
DE   RecName: Full=Ras-responsive element-binding protein 1;
DE            Short=RREB-1;
DE   AltName: Full=Finger protein in nuclear bodies;
DE   AltName: Full=Raf-responsive zinc finger protein LZ321;
DE   AltName: Full=Zinc finger motif enhancer-binding protein 1;
DE            Short=Zep-1;
GN   Name=RREB1; Synonyms=FINB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   RRFM_HUMAN              Reviewed;         262 AA.
AC   Q96E11; A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; Q5RKT1; Q5T7T0; Q5T7T1;
AC   Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5;
DE   RecName: Full=Ribosome-recycling factor, mitochondrial;
DE            Short=RRF;
DE   AltName: Full=Ribosome-releasing factor, mitochondrial;
DE   Flags: Precursor;
GN   Name=MRRF;
DR   GO; GO:0032790; P:ribosome disassembly; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
//
ID   RRF2M_HUMAN             Reviewed;         779 AA.
AC   Q969S9; A0AR28; Q8N6D8; Q8WYI0; Q9H6Z1;
DE   RecName: Full=Ribosome-releasing factor 2, mitochondrial;
DE            Short=RRF2mt;
DE   AltName: Full=Elongation factor G 2, mitochondrial;
DE            Short=EF-G2mt;
DE            Short=mEF-G 2;
DE   AltName: Full=Elongation factor G2;
DE            Short=hEFG2;
DE   Flags: Precursor;
GN   Name=GFM2; Synonyms=EFG2; ORFNames=MSTP027;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0032543; P:mitochondrial translation; IDA:UniProtKB.
DR   GO; GO:0032790; P:ribosome disassembly; IDA:UniProtKB.
//
ID   RRMJ2_HUMAN             Reviewed;         246 AA.
AC   Q9UI43; Q24JR8;
DE   RecName: Full=Putative ribosomal RNA methyltransferase 2;
DE            EC=2.1.1.-;
DE   AltName: Full=Protein ftsJ homolog 2;
DE   AltName: Full=rRNA (uridine-2'-O-)-methyltransferase;
GN   Name=FTSJ2; Synonyms=FJH1;
DR   GO; GO:0008650; F:rRNA (uridine-2'-O-)-methyltransferase activity; NAS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0031167; P:rRNA methylation; NAS:BHF-UCL.
DR   GO; GO:0006364; P:rRNA processing; NAS:BHF-UCL.
//
ID   RRN3_HUMAN              Reviewed;         651 AA.
AC   Q9NYV6; A2RTY9; Q6IPL4; Q9H4F0;
DE   RecName: Full=RNA polymerase I-specific transcription initiation factor RRN3;
DE   AltName: Full=Transcription initiation factor IA;
DE            Short=TIF-IA;
GN   Name=RRN3; Synonyms=TIFIA;
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0007028; P:cytoplasm organization; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:1902254; P:negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0007000; P:nucleolus organization; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:2000142; P:regulation of DNA-templated transcription, initiation; IEA:Ensembl.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:Ensembl.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   RRNAD_HUMAN             Reviewed;         475 AA.
AC   Q96FB5; D3DVC7; Q4VX71; Q5SZ03; Q9Y358;
DE   RecName: Full=Protein RRNAD1;
DE   AltName: Full=Ribosomal RNA adenine dimethylase domain-containing protein 1;
GN   Name=RRNAD1; Synonyms=C1orf66; ORFNames=CGI-41;
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
//
ID   RRP12_HUMAN             Reviewed;        1297 AA.
AC   Q5JTH9; B4DK00; E9PCK7; Q5JTH8; Q69YK4; Q96E87; Q9BUH3; Q9Y4C7;
DE   RecName: Full=RRP12-like protein;
GN   Name=RRP12; Synonyms=KIAA0690;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RRP15_HUMAN             Reviewed;         282 AA.
AC   Q9Y3B9;
DE   RecName: Full=RRP15-like protein;
DE   AltName: Full=Ribosomal RNA-processing protein 15;
GN   Name=RRP15; Synonyms=KIAA0507; ORFNames=CGI-115;
//
ID   RRP1B_HUMAN             Reviewed;         758 AA.
AC   Q14684; Q8TBZ4;
DE   RecName: Full=Ribosomal RNA processing protein 1 homolog B;
DE   AltName: Full=RRP1-like protein B;
GN   Name=RRP1B; Synonyms=KIAA0179;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
//
ID   RRP1_HUMAN              Reviewed;         461 AA.
AC   P56182; Q9NST5;
DE   RecName: Full=Ribosomal RNA processing protein 1 homolog A;
DE   AltName: Full=Novel nuclear protein 1;
DE            Short=NNP-1;
DE   AltName: Full=Nucleolar protein Nop52;
DE   AltName: Full=RRP1-like protein;
GN   Name=RRP1; Synonyms=D21S2056E, NNP1, NOP52, RRP1A;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   RRP36_HUMAN             Reviewed;         259 AA.
AC   Q96EU6; Q9BRF6; Q9P0C8;
DE   RecName: Full=Ribosomal RNA processing protein 36 homolog;
GN   Name=RRP36; Synonyms=C6orf153; ORFNames=HSPC253;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IDA:UniProtKB.
//
ID   RRP44_HUMAN             Reviewed;         958 AA.
AC   Q9Y2L1; A6NI21; B2RBL2; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2;
AC   Q9UG36;
DE   RecName: Full=Exosome complex exonuclease RRP44;
DE            EC=3.1.13.-;
DE            EC=3.1.26.-;
DE   AltName: Full=Protein DIS3 homolog;
DE   AltName: Full=Ribosomal RNA-processing protein 44;
GN   Name=DIS3; Synonyms=KIAA1008, RRP44;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IMP:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; IMP:UniProtKB.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0071034; P:CUT catabolic process; IMP:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IMP:GOC.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IMP:GOC.
DR   GO; GO:0016075; P:rRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; TAS:UniProtKB.
//
ID   RRP5_HUMAN              Reviewed;        1871 AA.
AC   Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1;
DE   RecName: Full=Protein RRP5 homolog;
DE   AltName: Full=NF-kappa-B-binding protein;
DE            Short=NFBP;
DE   AltName: Full=Programmed cell death protein 11;
GN   Name=PDCD11; Synonyms=KIAA0185;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   RRP7A_HUMAN             Reviewed;         280 AA.
AC   Q9Y3A4; A4FTX2; B2RBG4; Q0VAD0; Q5JZ94; Q6P4B5; Q8IVR9; Q8IVY0;
AC   Q8N5Q3; Q8NEY6; Q9Y3H5;
DE   RecName: Full=Ribosomal RNA-processing protein 7 homolog A;
DE   AltName: Full=Gastric cancer antigen Zg14;
GN   Name=RRP7A; ORFNames=CGI-96;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RRP8_HUMAN              Reviewed;         456 AA.
AC   O43159; Q7KZ78; Q9BVM6;
DE   RecName: Full=Ribosomal RNA-processing protein 8;
DE            EC=2.1.1.-;
DE   AltName: Full=Cerebral protein 1;
DE   AltName: Full=Nucleomethylin;
GN   Name=RRP8; Synonyms=KIAA0409, NML; ORFNames=hucep-1;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IMP:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; IDA:UniProtKB.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0046015; P:regulation of transcription by glucose; IMP:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RRP7B_HUMAN             Reviewed;         103 AA.
AC   Q9NSQ0;
DE   RecName: Full=Putative ribosomal RNA-processing protein 7 homolog B;
DE   AltName: Full=Putative gastric cancer antigen Zg14-like protein;
GN   Name=RRP7B;
//
ID   RRS1_HUMAN              Reviewed;         365 AA.
AC   Q15050; Q9BUX8;
DE   RecName: Full=Ribosome biogenesis regulatory protein homolog;
GN   Name=RRS1; Synonyms=KIAA0112, RRR;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
//
ID   RS10L_HUMAN             Reviewed;         176 AA.
AC   Q9NQ39;
DE   RecName: Full=Putative 40S ribosomal protein S10-like;
GN   Name=RPS10P5; Synonyms=RPS10L;
//
ID   RS10_HUMAN              Reviewed;         165 AA.
AC   P46783; B2R4E3; Q5TZC0;
DE   RecName: Full=40S ribosomal protein S10;
GN   Name=RPS10;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS11_HUMAN              Reviewed;         158 AA.
AC   P62280; B2R4F5; P04643; Q498Y6; Q6IRY0;
DE   RecName: Full=40S ribosomal protein S11;
GN   Name=RPS11;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS12_HUMAN              Reviewed;         132 AA.
AC   P25398; Q76M58;
DE   RecName: Full=40S ribosomal protein S12;
GN   Name=RPS12;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS13_HUMAN              Reviewed;         151 AA.
AC   P62277; B2R549; P19116; Q02546; Q29200; Q498Y0;
DE   RecName: Full=40S ribosomal protein S13;
GN   Name=RPS13;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0033119; P:negative regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS14_HUMAN              Reviewed;         151 AA.
AC   P62263; B2R5G5; D3DQG5; P06366; Q5BJI0;
DE   RecName: Full=40S ribosomal protein S14;
GN   Name=RPS14; ORFNames=PRO2640;
DR   GO; GO:0048027; F:mRNA 5'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; ISS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006417; P:regulation of translation; IMP:GOC.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IMP:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS15A_HUMAN             Reviewed;         130 AA.
AC   P62244; P39027; P39031; Q3MHD9; Q8C023; Q9BV24;
DE   RecName: Full=40S ribosomal protein S15a;
GN   Name=RPS15A; ORFNames=OK/SW-cl.82;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS15_HUMAN              Reviewed;         145 AA.
AC   P62841; A5D8V9; P11174; Q3KRA1; Q9UDC2;
DE   RecName: Full=40S ribosomal protein S15;
DE   AltName: Full=RIG protein;
GN   Name=RPS15; Synonyms=RIG;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0000056; P:ribosomal small subunit export from nucleus; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS16_HUMAN              Reviewed;         146 AA.
AC   P62249; B2RDD5; P17008;
DE   RecName: Full=40S ribosomal protein S16;
GN   Name=RPS16;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS17L_HUMAN             Reviewed;         135 AA.
AC   P0CW22;
DE   RecName: Full=40S ribosomal protein S17-like;
GN   Name=RPS17L;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RS17_HUMAN              Reviewed;         135 AA.
AC   P08708; B2R4U4;
DE   RecName: Full=40S ribosomal protein S17;
GN   Name=RPS17;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:RefGenome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; IBA:RefGenome.
DR   GO; GO:0006413; P:translational initiation; NAS:UniProtKB.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS18_HUMAN              Reviewed;         152 AA.
AC   P62269; P25232; Q5SUJ3; Q6IPF8;
DE   RecName: Full=40S ribosomal protein S18;
DE   AltName: Full=Ke-3;
DE            Short=Ke3;
GN   Name=RPS18; Synonyms=D6S218E;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:RefGenome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS19_HUMAN              Reviewed;         145 AA.
AC   P39019;
DE   RecName: Full=40S ribosomal protein S19;
GN   Name=RPS19;
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IMP:UniProtKB.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:UniProtKB.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0060266; P:negative regulation of respiratory burst involved in inflammatory response; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0007000; P:nucleolus organization; IMP:UniProtKB.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; TAS:HGNC.
DR   GO; GO:0060265; P:positive regulation of respiratory burst involved in inflammatory response; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
DR   GO; GO:0009991; P:response to extracellular stimulus; TAS:HGNC.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IMP:UniProtKB.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS20_HUMAN              Reviewed;         119 AA.
AC   P60866; B2R4F4; B4DW28; P17075; Q5M8S9;
DE   RecName: Full=40S ribosomal protein S20;
GN   Name=RPS20;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS21_HUMAN              Reviewed;          83 AA.
AC   P63220; P35265;
DE   RecName: Full=40S ribosomal protein S21;
GN   Name=RPS21;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
DR   GO; GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IBA:RefGenome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS23_HUMAN              Reviewed;         143 AA.
AC   P62266; P39028; Q6IB08;
DE   RecName: Full=40S ribosomal protein S23;
GN   Name=RPS23;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS24_HUMAN              Reviewed;         133 AA.
AC   P62847; E7EPK6; P16632; Q5T0P7; Q5T0P8; Q7Z3D1;
DE   RecName: Full=40S ribosomal protein S24;
GN   Name=RPS24;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0031369; F:translation initiation factor binding; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS25_HUMAN              Reviewed;         125 AA.
AC   P62851; B2R4M7; P25111;
DE   RecName: Full=40S ribosomal protein S25;
GN   Name=RPS25;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS26L_HUMAN             Reviewed;         115 AA.
AC   Q5JNZ5;
DE   RecName: Full=Putative 40S ribosomal protein S26-like 1;
GN   Name=RPS26P11; Synonyms=RPS26L1;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RS26_HUMAN              Reviewed;         115 AA.
AC   P62854; P02383; P70394; Q06722; Q3MHD8; Q6IRY4;
DE   RecName: Full=40S ribosomal protein S26;
GN   Name=RPS26;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0033119; P:negative regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS27A_HUMAN             Reviewed;         156 AA.
AC   P62979; P02248; P02249; P02250; P14798; P62988; Q29120; Q6LBL4;
AC   Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2;
AC   Q9UEG1; Q9UEK8; Q9UPK7;
DE   RecName: Full=Ubiquitin-40S ribosomal protein S27a;
DE   AltName: Full=Ubiquitin carboxyl extension protein 80;
DE   Contains:
DE     RecName: Full=Ubiquitin;
DE   Contains:
DE     RecName: Full=40S ribosomal protein S27a;
DE   Flags: Precursor;
GN   Name=RPS27A; Synonyms=UBA80, UBCEP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   RS27L_HUMAN             Reviewed;          84 AA.
AC   Q71UM5; Q9BTJ1;
DE   RecName: Full=40S ribosomal protein S27-like;
GN   Name=RPS27L;
DR   GO; GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0008494; F:translation activator activity; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:GOC.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0031571; P:mitotic G1 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:GOC.
DR   GO; GO:0006412; P:translation; IDA:UniProtKB.
//
ID   RS27_HUMAN              Reviewed;          84 AA.
AC   P42677; Q5T4L6;
DE   RecName: Full=40S ribosomal protein S27;
DE   AltName: Full=Metallopan-stimulin 1;
DE            Short=MPS-1;
GN   Name=RPS27; Synonyms=MPS1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS28_HUMAN              Reviewed;          69 AA.
AC   P62857; P25112;
DE   RecName: Full=40S ribosomal protein S28;
GN   Name=RPS28;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS29_HUMAN              Reviewed;          56 AA.
AC   P62273; A8MZ73; P30054;
DE   RecName: Full=40S ribosomal protein S29;
GN   Name=RPS29;
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS2_HUMAN               Reviewed;         293 AA.
AC   P15880; B2R5G0; D3DU82; Q3MIB1;
DE   RecName: Full=40S ribosomal protein S2;
DE   AltName: Full=40S ribosomal protein S4;
DE   AltName: Full=Protein LLRep3;
GN   Name=RPS2; Synonyms=RPS4;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0051347; P:positive regulation of transferase activity; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS30_HUMAN              Reviewed;          59 AA.
AC   P62861; Q05472; Q95261; Q9H5V4;
DE   RecName: Full=40S ribosomal protein S30;
GN   Name=FAU;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProt.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProt.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProt.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS3A_HUMAN              Reviewed;         264 AA.
AC   P61247; B2R4D4; D3DP05; P33443; P49241;
DE   RecName: Full=40S ribosomal protein S3a;
DE   AltName: Full=v-fos transformation effector protein;
DE            Short=Fte-1;
GN   Name=RPS3A; Synonyms=FTE1, MFTL;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:RefGenome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IMP:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:UniProtKB.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS3_HUMAN               Reviewed;         243 AA.
AC   P23396; B2R7N5; J3KN86; Q498B5; Q8NI95;
DE   RecName: Full=40S ribosomal protein S3;
GN   Name=RPS3; ORFNames=OK/SW-cl.26;
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0003906; F:DNA-(apurinic or apyrimidinic site) lyase activity; IDA:UniProtKB.
DR   GO; GO:0004519; F:endonuclease activity; IMP:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; NAS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051018; F:protein kinase A binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:UniProtKB.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:RefGenome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0045738; P:negative regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IMP:GOC.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:1902546; P:positive regulation of DNA N-glycosylase activity; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; NAS:UniProtKB.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS4X_HUMAN              Reviewed;         263 AA.
AC   P62701; P12631; P12750; P27576; P55831; Q14727; Q6IPY4;
DE   RecName: Full=40S ribosomal protein S4, X isoform;
DE   AltName: Full=SCR10;
DE   AltName: Full=Single copy abundant mRNA protein;
GN   Name=RPS4X; Synonyms=CCG2, RPS4, SCAR;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IMP:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IMP:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS4Y1_HUMAN             Reviewed;         263 AA.
AC   P22090; A8K9V4;
DE   RecName: Full=40S ribosomal protein S4, Y isoform 1;
GN   Name=RPS4Y1; Synonyms=RPS4Y; ORFNames=PRO2646;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IMP:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IMP:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS4Y2_HUMAN             Reviewed;         263 AA.
AC   Q8TD47; A6NIR6;
DE   RecName: Full=40S ribosomal protein S4, Y isoform 2;
GN   Name=RPS4Y2; Synonyms=RPS4Y2P;
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RS5_HUMAN               Reviewed;         204 AA.
AC   P46782; B2R4T2; Q96BN0;
DE   RecName: Full=40S ribosomal protein S5;
DE   Contains:
DE     RecName: Full=40S ribosomal protein S5, N-terminally processed;
GN   Name=RPS5;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0006450; P:regulation of translational fidelity; IGI:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IGI:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; IC:UniProtKB.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS6_HUMAN               Reviewed;         249 AA.
AC   P62753; P08227; P10660; Q4VBY7; Q8N6Z7;
DE   RecName: Full=40S ribosomal protein S6;
DE   AltName: Full=Phosphoprotein NP33;
GN   Name=RPS6; ORFNames=OK/SW-cl.2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0031929; P:TOR signaling; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS7_HUMAN               Reviewed;         194 AA.
AC   P62081; P23821; P24818; Q57Z92; Q6IPH1;
DE   RecName: Full=40S ribosomal protein S7;
GN   Name=RPS7;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS8_HUMAN               Reviewed;         208 AA.
AC   P62241; P09058; Q6IRL7;
DE   RecName: Full=40S ribosomal protein S8;
GN   Name=RPS8; ORFNames=OK/SW-cl.83;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RS9_HUMAN               Reviewed;         194 AA.
AC   P46781; A9C4C1; Q4QRK7; Q9BVZ0;
DE   RecName: Full=40S ribosomal protein S9;
GN   Name=RPS9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IMP:GOC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IMP:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RSAD1_HUMAN             Reviewed;         442 AA.
AC   Q9HA92; Q53HV8; Q86VC4; Q9BRY7; Q9NUS7;
DE   RecName: Full=Radical S-adenosyl methionine domain-containing protein 1, mitochondrial;
DE            EC=1.3.99.-;
DE   AltName: Full=Oxygen-independent coproporphyrinogen-III oxidase-like protein RSAD1;
DE   Flags: Precursor;
GN   Name=RSAD1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
//
ID   RSAD2_HUMAN             Reviewed;         361 AA.
AC   Q8WXG1; Q8WVI4;
DE   RecName: Full=Radical S-adenosyl methionine domain-containing protein 2;
DE   AltName: Full=Cytomegalovirus-induced gene 5 protein;
DE   AltName: Full=Viperin;
DE   AltName: Full=Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible;
GN   Name=RSAD2; Synonyms=CIG5;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0035710; P:CD4-positive, alpha-beta T cell activation; ISS:UniProtKB.
DR   GO; GO:0043367; P:CD4-positive, alpha-beta T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:UniProtKB.
DR   GO; GO:0034157; P:positive regulation of toll-like receptor 7 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034165; P:positive regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030278; P:regulation of ossification; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RSBN1_HUMAN             Reviewed;         802 AA.
AC   Q5VWQ0; A8K937; Q6AI21; Q8TC33; Q9HA80; Q9NUP6;
DE   RecName: Full=Round spermatid basic protein 1;
GN   Name=RSBN1;
//
ID   RSBNL_HUMAN             Reviewed;         846 AA.
AC   Q6PCB5; C9K0P1; Q6ZS58; Q6ZVI9; Q86X48;
DE   RecName: Full=Round spermatid basic protein 1-like protein;
GN   Name=RSBN1L;
//
ID   RSCA1_HUMAN             Reviewed;         617 AA.
AC   Q92681; B2RBP5;
DE   RecName: Full=Regulatory solute carrier protein family 1 member 1;
DE   AltName: Full=Transporter regulator RS1;
DE            Short=hRS1;
GN   Name=RSC1A1;
DR   GO; GO:0008200; F:ion channel inhibitor activity; TAS:ProtInc.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0051051; P:negative regulation of transport; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   RSF1_HUMAN              Reviewed;        1441 AA.
AC   Q96T23; Q86X86; Q9H3L8; Q9NVZ8; Q9NYU0;
DE   RecName: Full=Remodeling and spacing factor 1;
DE            Short=Rsf-1;
DE   AltName: Full=HBV pX-associated protein 8;
DE   AltName: Full=Hepatitis B virus X-associated protein;
DE   AltName: Full=p325 subunit of RSF chromatin-remodeling complex;
GN   Name=RSF1; Synonyms=HBXAP, XAP8;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
DR   GO; GO:0016584; P:nucleosome positioning; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; IDA:UniProtKB.
//
ID   RSG1_HUMAN              Reviewed;         258 AA.
AC   Q9BU20; Q5TEV7;
DE   RecName: Full=REM2- and Rab-like small GTPase 1;
GN   Name=RSG1; Synonyms=C1orf89;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0034613; P:cellular protein localization; ISS:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.
DR   GO; GO:0031338; P:regulation of vesicle fusion; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RSH6A_HUMAN             Reviewed;         717 AA.
AC   Q9H0K4; Q53FE2; Q6PEZ9;
DE   RecName: Full=Radial spoke head protein 6 homolog A;
DE   AltName: Full=Radial spoke head-like protein 1;
GN   Name=RSPH6A; Synonyms=RSHL1;
//
ID   RSH4A_HUMAN             Reviewed;         716 AA.
AC   Q5TD94; B4DSI1; Q3KP24; Q5TD95;
DE   RecName: Full=Radial spoke head protein 4 homolog A;
DE   AltName: Full=Radial spoke head-like protein 3;
GN   Name=RSPH4A; Synonyms=RSHL3;
DR   GO; GO:0035082; P:axoneme assembly; IMP:BHF-UCL.
DR   GO; GO:0003341; P:cilium movement; IMP:BHF-UCL.
//
ID   RSLAB_HUMAN             Reviewed;         203 AA.
AC   Q96S79; B3KV31;
DE   RecName: Full=Ras-like protein family member 10B;
DE   AltName: Full=Ras-like protein VTS58635;
DE   AltName: Full=Ras-related protein 17;
DE            Short=RRP17;
DE   Flags: Precursor;
GN   Name=RASL10B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0090277; P:positive regulation of peptide hormone secretion; ISS:UniProtKB.
DR   GO; GO:0003050; P:regulation of systemic arterial blood pressure by atrial natriuretic peptide; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RSLAA_HUMAN             Reviewed;         203 AA.
AC   Q92737; Q49AU5; Q6PI03;
DE   RecName: Full=Ras-like protein family member 10A;
DE   AltName: Full=Ras-like protein RRP22;
DE   AltName: Full=Ras-related protein on chromosome 22;
DE   Flags: Precursor;
GN   Name=RASL10A; Synonyms=RRP22;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   RSLBA_HUMAN             Reviewed;         242 AA.
AC   Q6T310; B2RN97;
DE   RecName: Full=Ras-like protein family member 11A;
GN   Name=RASL11A;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RSLBB_HUMAN             Reviewed;         248 AA.
AC   Q9BPW5; B2RC51; Q96KC5;
DE   RecName: Full=Ras-like protein family member 11B;
GN   Name=RASL11B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   RSMB_HUMAN              Reviewed;         240 AA.
AC   P14678; Q15490; Q6IB35; Q9UIS5;
DE   RecName: Full=Small nuclear ribonucleoprotein-associated proteins B and B';
DE            Short=snRNP-B;
DE   AltName: Full=Sm protein B/B';
DE            Short=Sm-B/B';
DE            Short=SmB/B';
GN   Name=SNRPB; Synonyms=COD, SNRPB1;
DR   GO; GO:0071208; F:histone pre-mRNA DCP binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   RSMN_HUMAN              Reviewed;         240 AA.
AC   P63162; P14648; P17135; Q0D2Q5;
DE   RecName: Full=Small nuclear ribonucleoprotein-associated protein N;
DE            Short=snRNP-N;
DE   AltName: Full=Sm protein D;
DE            Short=Sm-D;
DE   AltName: Full=Sm protein N;
DE            Short=Sm-N;
DE            Short=SmN;
DE   AltName: Full=Tissue-specific-splicing protein;
GN   Name=SNRPN; Synonyms=HCERN3, SMN;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
//
ID   RSPH1_HUMAN             Reviewed;         309 AA.
AC   Q8WYR4; B2RBN9; Q3MJA1;
DE   RecName: Full=Radial spoke head 1 homolog;
DE   AltName: Full=Cancer/testis antigen 79;
DE            Short=CT79;
DE   AltName: Full=Male meiotic metaphase chromosome-associated acidic protein;
DE   AltName: Full=Meichroacidin;
DE   AltName: Full=Testis-specific gene A2 protein;
GN   Name=RSPH1; Synonyms=TSA2, TSGA2;
DR   GO; GO:0035082; P:axoneme assembly; IMP:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   RSPH3_HUMAN             Reviewed;         560 AA.
AC   Q86UC2; Q96LQ5; Q96LX2; Q9BX75;
DE   RecName: Full=Radial spoke head protein 3 homolog;
DE   AltName: Full=Radial spoke head-like protein 2;
GN   Name=RSPH3; Synonyms=RSHL2, RSP3;
//
ID   RSPH9_HUMAN             Reviewed;         276 AA.
AC   Q9H1X1; A8K5T4; Q96NH9;
DE   RecName: Full=Radial spoke head protein 9 homolog;
GN   Name=RSPH9; Synonyms=C6orf206, MRPS18AL1;
DR   GO; GO:0035082; P:axoneme assembly; IMP:BHF-UCL.
DR   GO; GO:0003341; P:cilium movement; IMP:BHF-UCL.
//
ID   RSPO2_HUMAN             Reviewed;         243 AA.
AC   Q6UXX9; B3KVP0; Q4G0U4; Q8N6X6;
DE   RecName: Full=R-spondin-2;
DE   AltName: Full=Roof plate-specific spondin-2;
DE            Short=hRspo2;
DE   Flags: Precursor;
GN   Name=RSPO2; ORFNames=UNQ9384/PRO34209;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0060437; P:lung growth; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060535; P:trachea cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RSPO1_HUMAN             Reviewed;         263 AA.
AC   Q2MKA7; A2A420; Q0H8S6; Q14C72; Q5T0F2; Q8N7L5;
DE   RecName: Full=R-spondin-1;
DE   AltName: Full=Roof plate-specific spondin-1;
DE            Short=hRspo1;
DE   Flags: Precursor;
GN   Name=RSPO1;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000052; P:positive regulation of non-canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:2000254; P:regulation of male germ cell proliferation; IEA:Ensembl.
DR   GO; GO:0002090; P:regulation of receptor internalization; IDA:BHF-UCL.
//
ID   RSPO4_HUMAN             Reviewed;         234 AA.
AC   Q2I0M5; A2A2I6; Q9UGB2;
DE   RecName: Full=R-spondin-4;
DE   AltName: Full=Roof plate-specific spondin-4;
DE            Short=hRspo4;
DE   Flags: Precursor;
GN   Name=RSPO4; Synonyms=C20orf182;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RSPRY_HUMAN             Reviewed;         576 AA.
AC   Q96DX4; Q6UX21; Q8ND53;
DE   RecName: Full=RING finger and SPRY domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=RSPRY1; Synonyms=KIAA1972; ORFNames=UNQ328/PRO444;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RSPO3_HUMAN             Reviewed;         272 AA.
AC   Q9BXY4; B2RC27; Q5VTV4; Q96K87;
DE   RecName: Full=R-spondin-3;
DE   AltName: Full=Protein with TSP type-1 repeat;
DE            Short=hPWTSR;
DE   AltName: Full=Roof plate-specific spondin-3;
DE            Short=hRspo3;
DE   AltName: Full=Thrombospondin type-1 domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=RSPO3; Synonyms=PWTSR, THSD2;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
//
ID   RSRC1_HUMAN             Reviewed;         334 AA.
AC   Q96IZ7; A8K2R9; Q96QK2; Q9NZE5;
DE   RecName: Full=Serine/Arginine-related protein 53;
DE            Short=SRrp53;
DE   AltName: Full=Arginine/serine-rich coiled-coil protein 1;
GN   Name=RSRC1; Synonyms=SRRP53; ORFNames=BM-011;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; IDA:MGI.
//
ID   RSRC2_HUMAN             Reviewed;         434 AA.
AC   Q7L4I2; Q6N040; Q6NW16; Q9H864;
DE   RecName: Full=Arginine/serine-rich coiled-coil protein 2;
GN   Name=RSRC2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RSRP1_HUMAN             Reviewed;         290 AA.
AC   Q9BUV0; A8K917; Q49AA4; Q5TH71; Q9GZP6;
DE   RecName: Full=Arginine/serine-rich protein 1;
GN   Name=RSRP1; Synonyms=C1orf63; ORFNames=HT033, NPD014;
//
ID   RSSA_HUMAN              Reviewed;         295 AA.
AC   P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8;
AC   Q86VC0;
DE   RecName: Full=40S ribosomal protein SA;
DE   AltName: Full=37 kDa laminin receptor precursor;
DE            Short=37LRP;
DE   AltName: Full=37/67 kDa laminin receptor;
DE            Short=LRP/LR;
DE   AltName: Full=67 kDa laminin receptor;
DE            Short=67LR;
DE   AltName: Full=Colon carcinoma laminin-binding protein;
DE   AltName: Full=Laminin receptor 1;
DE            Short=LamR;
DE   AltName: Full=Laminin-binding protein precursor p40;
DE            Short=LBP/p40;
DE   AltName: Full=Multidrug resistance-associated protein MGr1-Ag;
DE   AltName: Full=NEM/1CHD4;
GN   Name=RPSA; Synonyms=LAMBR, LAMR1;
DR   GO; GO:0005055; F:laminin receptor activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:RefGenome.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
DR   GO; GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:RefGenome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:RefGenome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0006407; P:rRNA export from nucleus; IBA:RefGenome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; IC:UniProtKB.
DR   GO; GO:0006414; P:translational elongation; TAS:Reactome.
DR   GO; GO:0006413; P:translational initiation; TAS:Reactome.
DR   GO; GO:0006415; P:translational termination; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019083; P:viral transcription; TAS:Reactome.
//
ID   RSU1_HUMAN              Reviewed;         277 AA.
AC   Q15404; A8KA46; D3DRU3; Q6FI17;
DE   RecName: Full=Ras suppressor protein 1;
DE            Short=RSP-1;
DE            Short=Rsu-1;
GN   Name=RSU1; Synonyms=RSP1;
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   RT02_HUMAN              Reviewed;         296 AA.
AC   Q9Y399; Q5T899; Q9BSQ4;
DE   RecName: Full=28S ribosomal protein S2, mitochondrial;
DE            Short=MRP-S2;
DE            Short=S2mt;
GN   Name=MRPS2; ORFNames=CGI-91;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT05_HUMAN              Reviewed;         430 AA.
AC   P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4;
DE   RecName: Full=28S ribosomal protein S5, mitochondrial;
DE            Short=MRP-S5;
DE            Short=S5mt;
GN   Name=MRPS5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT06_HUMAN              Reviewed;         125 AA.
AC   P82932; B2R573; Q96Q64; Q9BSK8; Q9BW89;
DE   RecName: Full=28S ribosomal protein S6, mitochondrial;
DE            Short=MRP-S6;
DE            Short=S6mt;
GN   Name=MRPS6; Synonyms=C21orf101, RPMS6;
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT07_HUMAN              Reviewed;         242 AA.
AC   Q9Y2R9; B2R9N5; Q53GD6;
DE   RecName: Full=28S ribosomal protein S7, mitochondrial;
DE            Short=MRP-S7;
DE            Short=S7mt;
DE   AltName: Full=bMRP-27a;
DE            Short=bMRP27a;
DE   Flags: Precursor;
GN   Name=MRPS7;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
//
ID   RT09_HUMAN              Reviewed;         396 AA.
AC   P82933; Q6PG40;
DE   RecName: Full=28S ribosomal protein S9, mitochondrial;
DE            Short=MRP-S9;
DE            Short=S9mt;
DE   Flags: Precursor;
GN   Name=MRPS9; Synonyms=RPMS9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; NAS:UniProtKB.
DR   GO; GO:0043043; P:peptide biosynthetic process; IC:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT10_HUMAN              Reviewed;         201 AA.
AC   P82664; B2RE89; Q9H3E5; Q9NVR3;
DE   RecName: Full=28S ribosomal protein S10, mitochondrial;
DE            Short=MRP-S10;
DE            Short=S10mt;
GN   Name=MRPS10; ORFNames=MSTP040;
//
ID   RT11_HUMAN              Reviewed;         194 AA.
AC   P82912; B2RD52; Q969D7; Q96GI3; Q9BYC3;
DE   RecName: Full=28S ribosomal protein S11, mitochondrial;
DE            Short=MRP-S11;
DE            Short=S11mt;
DE   AltName: Full=Cervical cancer proto-oncogene 2 protein;
DE            Short=HCC-2;
DE   Flags: Precursor;
GN   Name=MRPS11; Synonyms=RPMS11; ORFNames=HCC2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT12_HUMAN              Reviewed;         138 AA.
AC   O15235; Q53X98;
DE   RecName: Full=28S ribosomal protein S12, mitochondrial;
DE            Short=MRP-S12;
DE            Short=S12mt;
DE   AltName: Full=MT-RPS12;
DE   Flags: Precursor;
GN   Name=MRPS12; Synonyms=RPMS12, RPSM12;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003735; F:structural constituent of ribosome; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT14_HUMAN              Reviewed;         128 AA.
AC   O60783; Q5R358;
DE   RecName: Full=28S ribosomal protein S14, mitochondrial;
DE            Short=MRP-S14;
DE            Short=S14mt;
GN   Name=MRPS14;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; TAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT15_HUMAN              Reviewed;         257 AA.
AC   P82914; B2RD82; Q9H2K1;
DE   RecName: Full=28S ribosomal protein S15, mitochondrial;
DE            Short=MRP-S15;
DE            Short=S15mt;
DE   Flags: Precursor;
GN   Name=MRPS15; Synonyms=RPMS15; ORFNames=DC37;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT16_HUMAN              Reviewed;         137 AA.
AC   Q9Y3D3; Q96Q60;
DE   RecName: Full=28S ribosomal protein S16, mitochondrial;
DE            Short=MRP-S16;
DE            Short=S16mt;
DE   Flags: Precursor;
GN   Name=MRPS16; Synonyms=RPMS16; ORFNames=CGI-132;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT17_HUMAN              Reviewed;         130 AA.
AC   Q9Y2R5; Q86X15;
DE   RecName: Full=28S ribosomal protein S17, mitochondrial;
DE            Short=MRP-S17;
DE            Short=S17mt;
DE   Flags: Precursor;
GN   Name=MRPS17; Synonyms=RPMS17; ORFNames=HSPC011;
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT18A_HUMAN             Reviewed;         196 AA.
AC   Q9NVS2; A6XND3; Q5QPA4;
DE   RecName: Full=28S ribosomal protein S18a, mitochondrial;
DE            Short=MRP-S18-a;
DE            Short=Mrps18a;
DE            Short=S18mt-a;
DE   AltName: Full=28S ribosomal protein S18-3, mitochondrial;
DE            Short=MRP-S18-3;
DE   Flags: Precursor;
GN   Name=MRPS18A;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT18B_HUMAN             Reviewed;         258 AA.
AC   Q9Y676; A6NDQ0; Q659G4; Q9BS27;
DE   RecName: Full=28S ribosomal protein S18b, mitochondrial;
DE            Short=MRP-S18-b;
DE            Short=Mrps18-b;
DE            Short=S18mt-b;
DE   AltName: Full=28S ribosomal protein S18-2, mitochondrial;
DE            Short=MRP-S18-2;
DE   Flags: Precursor;
GN   Name=MRPS18B; Synonyms=C6orf14; ORFNames=HSPC183, PTD017;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT18C_HUMAN             Reviewed;         142 AA.
AC   Q9Y3D5;
DE   RecName: Full=28S ribosomal protein S18c, mitochondrial;
DE            Short=MRP-S18-c;
DE            Short=Mrps18-c;
DE            Short=S18mt-c;
DE   AltName: Full=28S ribosomal protein S18-1, mitochondrial;
DE            Short=MRP-S18-1;
DE   Flags: Precursor;
GN   Name=MRPS18C; ORFNames=CGI-134;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT21_HUMAN              Reviewed;          87 AA.
AC   P82921; Q5TB11; Q9BST6;
DE   RecName: Full=28S ribosomal protein S21, mitochondrial;
DE            Short=MRP-S21;
DE            Short=S21mt;
GN   Name=MRPS21; Synonyms=RPMS21; ORFNames=MDS016;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT22_HUMAN              Reviewed;         360 AA.
AC   P82650;
DE   RecName: Full=28S ribosomal protein S22, mitochondrial;
DE            Short=MRP-S22;
DE            Short=S22mt;
GN   Name=MRPS22; Synonyms=C3orf5, RPMS22; ORFNames=GK002;
DR   GO; GO:0003735; F:structural constituent of ribosome; IDA:MGI.
//
ID   RT23_HUMAN              Reviewed;         190 AA.
AC   Q9Y3D9; B2R6V3; Q96Q24; Q9BWH8; Q9P053;
DE   RecName: Full=28S ribosomal protein S23, mitochondrial;
DE            Short=MRP-S23;
DE            Short=S23mt;
GN   Name=MRPS23; ORFNames=CGI-138, HSPC329;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT24_HUMAN              Reviewed;         167 AA.
AC   Q96EL2; A4D1U9; P82668; Q96Q23; Q9P047;
DE   RecName: Full=28S ribosomal protein S24, mitochondrial;
DE            Short=MRP-S24;
DE            Short=S24mt;
DE   AltName: Full=bMRP-47;
DE            Short=bMRP47;
DE   Flags: Precursor;
GN   Name=MRPS24; ORFNames=HSPC335;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
//
ID   RT25_HUMAN              Reviewed;         173 AA.
AC   P82663; Q9H7P5;
DE   RecName: Full=28S ribosomal protein S25, mitochondrial;
DE            Short=MRP-S25;
DE            Short=S25mt;
GN   Name=MRPS25; Synonyms=RPMS25;
//
ID   RT26_HUMAN              Reviewed;         205 AA.
AC   Q9BYN8; Q96Q58;
DE   RecName: Full=28S ribosomal protein S26, mitochondrial;
DE            Short=MRP-S26;
DE            Short=S26mt;
DE   AltName: Full=28S ribosomal protein S13, mitochondrial;
DE            Short=MRP-S13;
DE            Short=S13mt;
DE   Flags: Precursor;
GN   Name=MRPS26; Synonyms=C20orf193, RPMS13;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; NAS:UniProtKB.
DR   GO; GO:0043043; P:peptide biosynthetic process; IC:UniProtKB.
//
ID   RT27_HUMAN              Reviewed;         414 AA.
AC   Q92552; B4DRT2; Q6P1S1;
DE   RecName: Full=28S ribosomal protein S27, mitochondrial;
DE            Short=MRP-S27;
DE            Short=S27mt;
GN   Name=MRPS27; Synonyms=KIAA0264;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   RT28_HUMAN              Reviewed;         187 AA.
AC   Q9Y2Q9; B2RDZ7; Q96Q21;
DE   RecName: Full=28S ribosomal protein S28, mitochondrial;
DE            Short=MRP-S28;
DE            Short=S28mt;
DE   AltName: Full=28S ribosomal protein S35, mitochondrial;
DE            Short=MRP-S35;
DE            Short=S35mt;
DE   Flags: Precursor;
GN   Name=MRPS28; Synonyms=MRPS35; ORFNames=HSPC007;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   RT29_HUMAN              Reviewed;         398 AA.
AC   P51398; B4DP59; B4DY62; E7EM60; Q13044; Q68CT7; Q96Q20;
DE   RecName: Full=28S ribosomal protein S29, mitochondrial;
DE            Short=MRP-S29;
DE            Short=S29mt;
DE   AltName: Full=Death-associated protein 3;
DE            Short=DAP-3;
DE   AltName: Full=Ionizing radiation resistance conferring protein;
DE   Flags: Precursor;
GN   Name=DAP3; Synonyms=MRPS29;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008637; P:apoptotic mitochondrial changes; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
//
ID   RT30_HUMAN              Reviewed;         439 AA.
AC   Q9NP92; Q96I91; Q96Q19; Q9H0P8; Q9NSF9; Q9NZ76;
DE   RecName: Full=28S ribosomal protein S30, mitochondrial;
DE            Short=MRP-S30;
DE            Short=S30mt;
DE   AltName: Full=Programmed cell death protein 9;
GN   Name=MRPS30; Synonyms=PDCD9; ORFNames=BM-047;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
//
ID   RT31_HUMAN              Reviewed;         395 AA.
AC   Q92665; B2RCS3; Q5VYC8; Q8WTV8;
DE   RecName: Full=28S ribosomal protein S31, mitochondrial;
DE            Short=MRP-S31;
DE            Short=S31mt;
DE   AltName: Full=Imogen 38;
DE   Flags: Precursor;
GN   Name=MRPS31; Synonyms=IMOGN38;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
//
ID   RT35_HUMAN              Reviewed;         323 AA.
AC   P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14;
AC   Q9P1R5;
DE   RecName: Full=28S ribosomal protein S35, mitochondrial;
DE            Short=MRP-S35;
DE            Short=S35mt;
DE   AltName: Full=28S ribosomal protein S28, mitochondrial;
DE            Short=MRP-S28;
DE            Short=S28mt;
DE   Flags: Precursor;
GN   Name=MRPS35; Synonyms=MRPS28; ORFNames=HDCMD11P, MDS023, PSEC0213;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; NAS:UniProtKB.
DR   GO; GO:0043043; P:peptide biosynthetic process; IC:UniProtKB.
//
ID   RT34_HUMAN              Reviewed;         218 AA.
AC   P82930; Q9BVI7;
DE   RecName: Full=28S ribosomal protein S34, mitochondrial;
DE            Short=MRP-S34;
DE            Short=S34mt;
GN   Name=MRPS34;
//
ID   RT36_HUMAN              Reviewed;         103 AA.
AC   P82909; Q9H2H4;
DE   RecName: Full=28S ribosomal protein S36, mitochondrial;
DE            Short=MRP-S36;
DE            Short=S36mt;
GN   Name=MRPS36; ORFNames=DC47;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT33_HUMAN              Reviewed;         106 AA.
AC   Q9Y291;
DE   RecName: Full=28S ribosomal protein S33, mitochondrial;
DE            Short=MRP-S33;
DE            Short=S33mt;
GN   Name=MRPS33; ORFNames=CGI-139, PTD003;
DR   GO; GO:0003735; F:structural constituent of ribosome; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   RT4I1_HUMAN             Reviewed;         396 AA.
AC   Q8WWV3; Q8N9B3; Q8WZ66; Q9BRA4;
DE   RecName: Full=Reticulon-4-interacting protein 1, mitochondrial;
DE   AltName: Full=NOGO-interacting mitochondrial protein;
DE   Flags: Precursor;
GN   Name=RTN4IP1; Synonyms=NIMP;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   RT63_HUMAN              Reviewed;         102 AA.
AC   Q9BQC6; A2A332;
DE   RecName: Full=Ribosomal protein 63, mitochondrial;
DE            Short=hMRP63;
DE   AltName: Full=Mitochondrial ribosomal protein 63;
DE   AltName: Full=Mitochondrial ribosomal protein L57;
GN   Name=MRPL57; Synonyms=MRP63;
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; IEA:Ensembl.
//
ID   RTBDN_HUMAN             Reviewed;         229 AA.
AC   Q9BSG5; F1T0I8; Q9BWT5;
DE   RecName: Full=Retbindin;
DE   Flags: Precursor;
GN   Name=RTBDN;
//
ID   RTCA_HUMAN              Reviewed;         366 AA.
AC   O00442; Q5VVL5; Q5VVL6; Q96E99;
DE   RecName: Full=RNA 3'-terminal phosphate cyclase;
DE            Short=RNA cyclase;
DE            Short=RNA-3'-phosphate cyclase;
DE            EC=6.5.1.4;
DE   AltName: Full=RNA terminal phosphate cyclase domain-containing protein 1;
DE            Short=RTC domain-containing protein 1;
GN   Name=RTCA; Synonyms=RPC, RPC1, RTC1, RTCD1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003963; F:RNA-3'-phosphate cyclase activity; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   RTCB_HUMAN              Reviewed;         505 AA.
AC   Q9Y3I0; B2R6A8; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3;
DE   RecName: Full=tRNA-splicing ligase RtcB homolog;
DE            EC=6.5.1.3;
GN   Name=RTCB; Synonyms=C22orf28; ORFNames=HSPC117;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003972; F:RNA ligase (ATP) activity; IDA:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IDA:UniProtKB.
//
ID   RTDR1_HUMAN             Reviewed;         348 AA.
AC   Q9UHP6;
DE   RecName: Full=Rhabdoid tumor deletion region protein 1;
GN   Name=RTDR1;
//
ID   RTEL1_HUMAN             Reviewed;        1219 AA.
AC   Q9NZ71; A2A397; A2A398; B4DRM5; B4DYM3; B4E3N6; E1P5J4; E1P5J5;
AC   Q5JTV3; Q5JTV4; Q9BW37; Q9H402; Q9H4X6; Q9NX25; Q9NZ73; Q9UPR4;
AC   Q9Y4R6;
DE   RecName: Full=Regulator of telomere elongation helicase 1;
DE            EC=3.6.4.12;
DE   AltName: Full=Novel helicase-like;
GN   Name=RTEL1; Synonyms=C20orf41, KIAA1088, NHL;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IMP:UniProtKB.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IMP:GOC.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
//
ID   RTF1_HUMAN              Reviewed;         710 AA.
AC   Q92541; Q96BX6;
DE   RecName: Full=RNA polymerase-associated protein RTF1 homolog;
GN   Name=RTF1; Synonyms=KIAA0252;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RTF2_HUMAN              Reviewed;         306 AA.
AC   Q9BY42; E1P5Z9; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3;
DE   RecName: Full=Protein RTF2 homolog;
DE   AltName: Full=Replication termination factor 2 domain-containing protein 1;
GN   Name=RTFDC1; Synonyms=C20orf43;
GN   ORFNames=AD-007, CDA05, HSPC164, HSPC169;
//
ID   RTKN_HUMAN              Reviewed;         563 AA.
AC   Q9BST9; H7BXD4; Q8WVN1; Q96PT6; Q9HB05;
DE   RecName: Full=Rhotekin;
GN   Name=RTKN; Synonyms=RTKN1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017049; F:GTP-Rho binding; IDA:UniProtKB.
DR   GO; GO:0005095; F:GTPase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   RTKN2_HUMAN             Reviewed;         609 AA.
AC   Q8IZC4; Q3ZCR1; Q68DZ6; Q8N8K1; Q8TAV2;
DE   RecName: Full=Rhotekin-2;
DE   AltName: Full=Pleckstrin homology domain-containing family K member 1;
DE            Short=PH domain-containing family K member 1;
GN   Name=RTKN2; Synonyms=PLEKHK1;
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   RTL1_HUMAN              Reviewed;        1358 AA.
AC   A6NKG5; E9PKS8;
DE   RecName: Full=Retrotransposon-like protein 1;
DE   AltName: Full=Mammalian retrotransposon derived protein 1;
DE   AltName: Full=Paternally expressed gene 11 protein;
DE   AltName: Full=Retrotransposon-derived protein PEG11;
GN   Name=RTL1; Synonyms=MAR1, MART1, PEG11;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   RTN1_HUMAN              Reviewed;         776 AA.
AC   Q16799; Q16800; Q16801; Q5BKZ4; Q9BQ59;
DE   RecName: Full=Reticulon-1;
DE   AltName: Full=Neuroendocrine-specific protein;
GN   Name=RTN1; Synonyms=NSP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IEP:UniProtKB.
//
ID   RTN2_HUMAN              Reviewed;         545 AA.
AC   O75298; O60509; Q7RTM6; Q7RTN1; Q7RTN2;
DE   RecName: Full=Reticulon-2;
DE   AltName: Full=Neuroendocrine-specific protein-like 1;
DE            Short=NSP-like protein 1;
DE   AltName: Full=Neuroendocrine-specific protein-like I;
DE            Short=NSP-like protein I;
DE            Short=NSPLI;
GN   Name=RTN2; Synonyms=NSPL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0065002; P:intracellular protein transmembrane transport; IEA:Ensembl.
DR   GO; GO:0046324; P:regulation of glucose import; IEA:Ensembl.
//
ID   RTN3_HUMAN              Reviewed;        1032 AA.
AC   O95197; B3KQS2; B7Z308; B7Z4M0; F5H774; Q147U9; Q496K2; Q53GN3;
AC   Q59EP0; Q5UEP2; Q6T930; Q7RTM7; Q7RTM8; Q7RTN3;
DE   RecName: Full=Reticulon-3;
DE   AltName: Full=Homolog of ASY protein;
DE            Short=HAP;
DE   AltName: Full=Neuroendocrine-specific protein-like 2;
DE            Short=NSP-like protein 2;
DE   AltName: Full=Neuroendocrine-specific protein-like II;
DE            Short=NSP-like protein II;
DE            Short=NSPLII;
GN   Name=RTN3; Synonyms=ASYIP, NSPL2;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IMP:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   RTN4R_HUMAN             Reviewed;         473 AA.
AC   Q9BZR6; D3DX28;
DE   RecName: Full=Reticulon-4 receptor;
DE   AltName: Full=Nogo receptor;
DE            Short=NgR;
DE   AltName: Full=Nogo-66 receptor;
DE   Flags: Precursor;
GN   Name=RTN4R; Synonyms=NOGOR; ORFNames=UNQ330/PRO526;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0007409; P:axonogenesis; NAS:UniProtKB.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
//
ID   RTN4_HUMAN              Reviewed;        1192 AA.
AC   Q9NQC3; O94962; Q7L7Q5; Q7L7Q6; Q7L7Q8; Q8IUA4; Q96B16; Q9BXG5;
AC   Q9H212; Q9H3I3; Q9UQ42; Q9Y293; Q9Y2Y7; Q9Y5U6;
DE   RecName: Full=Reticulon-4;
DE   AltName: Full=Foocen;
DE   AltName: Full=Neurite outgrowth inhibitor;
DE            Short=Nogo protein;
DE   AltName: Full=Neuroendocrine-specific protein;
DE            Short=NSP;
DE   AltName: Full=Neuroendocrine-specific protein C homolog;
DE   AltName: Full=RTN-x;
DE   AltName: Full=Reticulon-5;
GN   Name=RTN4; Synonyms=KIAA0886, NOGO; ORFNames=My043, SP1507;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007413; P:axonal fasciculation; ISS:UniProtKB.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0021801; P:cerebral cortex radial glia guided migration; ISS:UniProtKB.
DR   GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IMP:UniProtKB.
DR   GO; GO:0030517; P:negative regulation of axon extension; IDA:UniProtKB.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:DFLAT.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:2000172; P:regulation of branching morphogenesis of a nerve; ISS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IDA:MGI.
//
ID   RTP1_HUMAN              Reviewed;         263 AA.
AC   P59025;
DE   RecName: Full=Receptor-transporting protein 1;
GN   Name=RTP1;
DR   GO; GO:0031849; F:olfactory receptor binding; IMP:HGNC.
DR   GO; GO:0051205; P:protein insertion into membrane; IDA:HGNC.
//
ID   RTP3_HUMAN              Reviewed;         232 AA.
AC   Q9BQQ7; A2RRP6;
DE   RecName: Full=Receptor-transporting protein 3;
DE   AltName: Full=Transmembrane protein 7;
GN   Name=RTP3; Synonyms=TMEM7;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:HGNC.
DR   GO; GO:0006612; P:protein targeting to membrane; IDA:HGNC.
//
ID   RTP4_HUMAN              Reviewed;         246 AA.
AC   Q96DX8; Q9H4F3;
DE   RecName: Full=Receptor-transporting protein 4;
DE   AltName: Full=28 kDa interferon-responsive protein;
GN   Name=RTP4; Synonyms=IFRG28;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:HGNC.
DR   GO; GO:0006612; P:protein targeting to membrane; IDA:HGNC.
//
ID   RTP5_HUMAN              Reviewed;         572 AA.
AC   Q14D33; Q8N2A5;
DE   RecName: Full=Receptor-transporting protein 5;
DE   AltName: Full=CXXC-type zinc finger protein 11;
GN   Name=RTP5; Synonyms=C2orf85, CXXC11;
//
ID   RTP2_HUMAN              Reviewed;         225 AA.
AC   Q5QGT7; Q6NVH4;
DE   RecName: Full=Receptor-transporting protein 2;
GN   Name=RTP2;
DR   GO; GO:0031849; F:olfactory receptor binding; IMP:HGNC.
DR   GO; GO:0051205; P:protein insertion into membrane; IDA:HGNC.
//
ID   RTTN_HUMAN              Reviewed;        2226 AA.
AC   Q86VV8; Q68CS9; Q6ZRL8; Q6ZTK3; Q86TG4; Q8N8N8; Q8TBQ4; Q96IN9;
AC   Q9UFJ4;
DE   RecName: Full=Rotatin;
GN   Name=RTTN;
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
//
ID   RU17_HUMAN              Reviewed;         437 AA.
AC   P08621; B3KUA3; P78493; P78494; Q15364; Q15686; Q15687; Q15689;
AC   Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6;
DE   RecName: Full=U1 small nuclear ribonucleoprotein 70 kDa;
DE            Short=U1 snRNP 70 kDa;
DE            Short=U1-70K;
DE            Short=snRNP70;
GN   Name=SNRNP70; Synonyms=RNPU1Z, RPU1, SNRP70, U1AP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   RU1C_HUMAN              Reviewed;         159 AA.
AC   P09234; Q5TAL3;
DE   RecName: Full=U1 small nuclear ribonucleoprotein C;
DE            Short=U1 snRNP C;
DE            Short=U1-C;
DE            Short=U1C;
GN   Name=SNRPC;
DR   GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0000395; P:mRNA 5'-splice site recognition; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   RU2A_HUMAN              Reviewed;         255 AA.
AC   P09661; B2R5I6; Q8TBD2;
DE   RecName: Full=U2 small nuclear ribonucleoprotein A';
DE            Short=U2 snRNP A';
GN   Name=SNRPA1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   RU2B_HUMAN              Reviewed;         225 AA.
AC   P08579; B2R7J3; D3DW21; Q9UJD4;
DE   RecName: Full=U2 small nuclear ribonucleoprotein B'';
DE            Short=U2 snRNP B'';
GN   Name=SNRPB2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017069; F:snRNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   RUAS1_HUMAN             Reviewed;         236 AA.
AC   Q66K80; Q8NA07;
DE   RecName: Full=Putative uncharacterized protein RUSC1-AS1;
DE   AltName: Full=RUSC1 antisense RNA 1;
DE   AltName: Full=RUSC1 antisense gene protein 1;
GN   Name=RUSC1-AS1; Synonyms=C1orf104;
//
ID   RUBIC_HUMAN             Reviewed;         972 AA.
AC   Q92622; Q96CK5;
DE   RecName: Full=Run domain Beclin-1 interacting and cysteine-rich containing protein;
DE            Short=Rubicon;
DE   AltName: Full=Beclin-1 associated RUN domain containing protein;
DE            Short=Baron;
GN   Name=KIAA0226;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IMP:UniProtKB.
//
ID   RUFY1_HUMAN             Reviewed;         708 AA.
AC   Q96T51; Q59FF3; Q71S93; Q9H6I3;
DE   RecName: Full=RUN and FYVE domain-containing protein 1;
DE   AltName: Full=FYVE-finger protein EIP1;
DE   AltName: Full=La-binding protein 1;
DE   AltName: Full=Rab4-interacting protein;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 12;
GN   Name=RUFY1; Synonyms=RABIP4, ZFYVE12;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
//
ID   RUFY2_HUMAN             Reviewed;         655 AA.
AC   Q8WXA3; B3KXB2; B4DFR0; Q5TC48; Q8IW33; Q96P51; Q9P1Z1;
DE   RecName: Full=RUN and FYVE domain-containing protein 2;
DE   AltName: Full=Rab4-interacting protein related;
GN   Name=RUFY2; Synonyms=KIAA1537, RABIP4R;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   RUFY3_HUMAN             Reviewed;         469 AA.
AC   Q7L099; B3KM25; B4DYW7; D9N163; O94948; Q9UI00;
DE   RecName: Full=Protein RUFY3;
DE   AltName: Full=Rap2-interacting protein x;
DE            Short=RIPx;
DE   AltName: Full=Single axon-regulated protein;
DE            Short=Singar;
GN   Name=RUFY3; Synonyms=KIAA0871;
DR   GO; GO:0050771; P:negative regulation of axonogenesis; ISS:HGNC.
//
ID   RUFY4_HUMAN             Reviewed;         571 AA.
AC   Q6ZNE9; Q6ZR96;
DE   RecName: Full=RUN and FYVE domain-containing protein 4;
GN   Name=RUFY4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   RUIT1_HUMAN             Reviewed;         129 AA.
AC   Q9H7H1;
DE   RecName: Full=Putative uncharacterized protein encoded by RUNX1-IT1;
DE   AltName: Full=RUNX1 intronic transcript 1;
GN   Name=RUNX1-IT1; Synonyms=C21orf96;
//
ID   RUN3A_HUMAN             Reviewed;         446 AA.
AC   Q59EK9; B2R974; O15483; O60651; Q7Z3S2; Q9UF50;
DE   RecName: Full=RUN domain-containing protein 3A;
DE   AltName: Full=Rap2-interacting protein 8;
DE            Short=RPIP-8;
GN   Name=RUNDC3A; Synonyms=RAP2IP, RPIP8;
DR   GO; GO:0030250; F:guanylate cyclase activator activity; IEA:Ensembl.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
DR   GO; GO:0030828; P:positive regulation of cGMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
//
ID   RUN3B_HUMAN             Reviewed;         473 AA.
AC   Q96NL0; B4DFD0; E9PBR4; Q8IWW5; Q8NB55; Q8TBG7;
DE   RecName: Full=RUN domain-containing protein 3B;
DE   AltName: Full=Rap2-binding protein 9;
DE   AltName: Full=Rap2-interacting protein 9;
DE            Short=RPIP-9;
GN   Name=RUNDC3B; Synonyms=RPIB9, RPIP9;
//
ID   RUND1_HUMAN             Reviewed;         613 AA.
AC   Q96C34; Q6Y2K8; Q8IXT9; Q8N3W1;
DE   RecName: Full=RUN domain-containing protein 1;
GN   Name=RUNDC1; ORFNames=LP5161;
//
ID   RUNX1_HUMAN             Reviewed;         453 AA.
AC   Q01196; A8MV94; B2RMS4; D3DSG1; O60472; O60473; O76047; O76089;
AC   Q13081; Q13755; Q13756; Q13757; Q13758; Q13759; Q15341; Q15343;
AC   Q16122; Q16284; Q16285; Q16286; Q16346; Q16347; Q92479;
DE   RecName: Full=Runt-related transcription factor 1;
DE   AltName: Full=Acute myeloid leukemia 1 protein;
DE   AltName: Full=Core-binding factor subunit alpha-2;
DE            Short=CBF-alpha-2;
DE   AltName: Full=Oncogene AML-1;
DE   AltName: Full=Polyomavirus enhancer-binding protein 2 alpha B subunit;
DE            Short=PEA2-alpha B;
DE            Short=PEBP2-alpha B;
DE   AltName: Full=SL3-3 enhancer factor 1 alpha B subunit;
DE   AltName: Full=SL3/AKV core-binding factor alpha B subunit;
GN   Name=RUNX1; Synonyms=AML1, CBFA2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000975; F:regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; TAS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030099; P:myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0002318; P:myeloid progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0030853; P:negative regulation of granulocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0030854; P:positive regulation of granulocyte differentiation; IMP:UniProtKB.
DR   GO; GO:2000872; P:positive regulation of progesterone secretion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0071336; P:regulation of hair follicle cell proliferation; IEA:Ensembl.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RUNX2_HUMAN             Reviewed;         521 AA.
AC   Q13950; O14614; O14615; O95181;
DE   RecName: Full=Runt-related transcription factor 2;
DE   AltName: Full=Acute myeloid leukemia 3 protein;
DE   AltName: Full=Core-binding factor subunit alpha-1;
DE            Short=CBF-alpha-1;
DE   AltName: Full=Oncogene AML-3;
DE   AltName: Full=Osteoblast-specific transcription factor 2;
DE            Short=OSF-2;
DE   AltName: Full=Polyomavirus enhancer-binding protein 2 alpha A subunit;
DE            Short=PEA2-alpha A;
DE            Short=PEBP2-alpha A;
DE   AltName: Full=SL3-3 enhancer factor 1 alpha A subunit;
DE   AltName: Full=SL3/AKV core-binding factor alpha A subunit;
GN   Name=RUNX2; Synonyms=AML3, CBFA1, OSF2, PEBP2A;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; ISS:BHF-UCL.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; TAS:UniProtKB.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:UniProtKB.
DR   GO; GO:0002051; P:osteoblast fate commitment; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:1901522; P:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   RUNX3_HUMAN             Reviewed;         415 AA.
AC   Q13761; B1AJV5; Q12969; Q13760;
DE   RecName: Full=Runt-related transcription factor 3;
DE   AltName: Full=Acute myeloid leukemia 2 protein;
DE   AltName: Full=Core-binding factor subunit alpha-3;
DE            Short=CBF-alpha-3;
DE   AltName: Full=Oncogene AML-2;
DE   AltName: Full=Polyomavirus enhancer-binding protein 2 alpha C subunit;
DE            Short=PEA2-alpha C;
DE            Short=PEBP2-alpha C;
DE   AltName: Full=SL3-3 enhancer factor 1 alpha C subunit;
DE   AltName: Full=SL3/AKV core-binding factor alpha C subunit;
GN   Name=RUNX3; Synonyms=AML2, CBFA3, PEBP2A3;
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0048935; P:peripheral nervous system neuron development; TAS:BHF-UCL.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   RUSC2_HUMAN             Reviewed;        1516 AA.
AC   Q8N2Y8; A2RU62; A7E2A9; O15080; Q5W134; Q641Q6; Q6P1W7;
DE   RecName: Full=Iporin;
DE   AltName: Full=Interacting protein of Rab1;
DE   AltName: Full=RUN and SH3 domain-containing protein 2;
GN   Name=RUSC2; Synonyms=KIAA0375;
//
ID   RUSC1_HUMAN             Reviewed;         902 AA.
AC   Q9BVN2; B3KWM9; Q5T9U9; Q5T9V0; Q5T9V1; Q5T9V2; Q9UPY4; Q9Y4T5;
DE   RecName: Full=RUN and SH3 domain-containing protein 1;
DE   AltName: Full=New molecule containing SH3 at the carboxy-terminus;
DE            Short=Nesca;
GN   Name=RUSC1; Synonyms=NESCA;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
//
ID   RUSD1_HUMAN             Reviewed;         312 AA.
AC   Q9UJJ7; D3DU66;
DE   RecName: Full=RNA pseudouridylate synthase domain-containing protein 1;
DE   AltName: Full=Ribosomal large subunit pseudouridine synthase C-like protein;
GN   Name=RPUSD1; Synonyms=C16orf40, RLUCL;
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
//
ID   RUSD2_HUMAN             Reviewed;         545 AA.
AC   Q8IZ73; Q7L989; Q92939; Q96IA7; Q96N50;
DE   RecName: Full=RNA pseudouridylate synthase domain-containing protein 2;
GN   Name=RPUSD2; Synonyms=C15orf19;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
//
ID   RUSD3_HUMAN             Reviewed;         351 AA.
AC   Q6P087; B4DS39; Q6P6A9; Q8N1B2; Q8NAV3;
DE   RecName: Full=RNA pseudouridylate synthase domain-containing protein 3;
GN   Name=RPUSD3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
//
ID   RUSD4_HUMAN             Reviewed;         377 AA.
AC   Q96CM3; E9PML2; Q96K56;
DE   RecName: Full=RNA pseudouridylate synthase domain-containing protein 4;
GN   Name=RPUSD4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
//
ID   RUVB1_HUMAN             Reviewed;         456 AA.
AC   Q9Y265; B2R5S0; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9;
DE   RecName: Full=RuvB-like 1;
DE            EC=3.6.4.12;
DE   AltName: Full=49 kDa TATA box-binding protein-interacting protein;
DE            Short=49 kDa TBP-interacting protein;
DE   AltName: Full=54 kDa erythrocyte cytosolic protein;
DE            Short=ECP-54;
DE   AltName: Full=INO80 complex subunit H;
DE   AltName: Full=Nuclear matrix protein 238;
DE            Short=NMP 238;
DE   AltName: Full=Pontin 52;
DE   AltName: Full=TIP49a;
DE   AltName: Full=TIP60-associated protein 54-alpha;
DE            Short=TAP54-alpha;
GN   Name=RUVBL1; Synonyms=INO80H, NMP238, TIP49, TIP49A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:Reactome.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RUVB2_HUMAN             Reviewed;         463 AA.
AC   Q9Y230; Q6FIB9; Q6PK27; Q9Y361;
DE   RecName: Full=RuvB-like 2;
DE            EC=3.6.4.12;
DE   AltName: Full=48 kDa TATA box-binding protein-interacting protein;
DE            Short=48 kDa TBP-interacting protein;
DE   AltName: Full=51 kDa erythrocyte cytosolic protein;
DE            Short=ECP-51;
DE   AltName: Full=INO80 complex subunit J;
DE   AltName: Full=Repressing pontin 52;
DE            Short=Reptin 52;
DE   AltName: Full=TIP49b;
DE   AltName: Full=TIP60-associated protein 54-beta;
DE            Short=TAP54-beta;
GN   Name=RUVBL2; Synonyms=INO80J, TIP48, TIP49B; ORFNames=CGI-46;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0031490; F:chromatin DNA binding; IDA:UniProt.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IMP:UniProt.
DR   GO; GO:0034644; P:cellular response to UV; IMP:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IMP:UniProt.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0071169; P:establishment of protein localization to chromatin; IMP:UniProt.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0071899; P:negative regulation of estrogen receptor binding; IMP:UniProt.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IMP:UniProt.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProt.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0071733; P:transcriptional activation by promoter-enhancer looping; IMP:UniProt.
//
ID   RUXE_HUMAN              Reviewed;          92 AA.
AC   P62304; B2R5B9; P08578; Q15498; Q5BKT2;
DE   RecName: Full=Small nuclear ribonucleoprotein E;
DE            Short=snRNP-E;
DE   AltName: Full=Sm protein E;
DE            Short=Sm-E;
DE            Short=SmE;
GN   Name=SNRPE;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042633; P:hair cycle; IMP:UniProtKB.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000245; P:spliceosomal complex assembly; NAS:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   RUXGL_HUMAN             Reviewed;          76 AA.
AC   A8MWD9;
DE   RecName: Full=Small nuclear ribonucleoprotein G-like protein;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   RUXF_HUMAN              Reviewed;          86 AA.
AC   P62306; A2VCR2; B2R498; Q15356; Q6IBQ1; Q6P4I0;
DE   RecName: Full=Small nuclear ribonucleoprotein F;
DE            Short=snRNP-F;
DE   AltName: Full=Sm protein F;
DE            Short=Sm-F;
DE            Short=SmF;
GN   Name=SNRPF; Synonyms=PBSCF;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   RUXG_HUMAN              Reviewed;          76 AA.
AC   P62308; D6W5G6; Q15357; Q6IB86;
DE   RecName: Full=Small nuclear ribonucleoprotein G;
DE            Short=snRNP-G;
DE   AltName: Full=Sm protein G;
DE            Short=Sm-G;
DE            Short=SmG;
GN   Name=SNRPG; Synonyms=PBSCG;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; NAS:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   RWD2A_HUMAN             Reviewed;         292 AA.
AC   Q9UIY3; E1P548; Q2M3R3; Q96FH1;
DE   RecName: Full=RWD domain-containing protein 2A;
GN   Name=RWDD2A; Synonyms=RWDD2;
//
ID   RWD2B_HUMAN             Reviewed;         319 AA.
AC   P57060;
DE   RecName: Full=RWD domain-containing protein 2B;
GN   Name=RWDD2B; Synonyms=C21orf6; ORFNames=GL011;
//
ID   RWDD1_HUMAN             Reviewed;         243 AA.
AC   Q9H446; A8K3W2; A8MT24; Q9Y313; Q9Y6B3;
DE   RecName: Full=RWD domain-containing protein 1;
DE   AltName: Full=DRG family-regulatory protein 2;
GN   Name=RWDD1; Synonyms=DFRP2; ORFNames=CGI-24, PTD013;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RWDD3_HUMAN             Reviewed;         267 AA.
AC   Q9Y3V2; A6NP44; A8K9F0; C9J9L7; C9JI45; Q08AJ7; Q6FID3; Q9BX35;
DE   RecName: Full=RWD domain-containing protein 3;
DE   AltName: Full=RWD-containing sumoylation enhancer;
GN   Name=RWDD3; Synonyms=RSUME;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   RWDD4_HUMAN             Reviewed;         188 AA.
AC   Q6NW29; B2RDE9; Q75LA9; Q8WVW2;
DE   RecName: Full=RWD domain-containing protein 4;
DE   AltName: Full=Protein FAM28A;
GN   Name=RWDD4; Synonyms=FAM28A, RWDD4A;
//
ID   RXFP1_HUMAN             Reviewed;         757 AA.
AC   Q9HBX9; B4DHD1; B4DTV2; Q2M215; Q3KU24; Q3KU25; Q3KU26;
DE   RecName: Full=Relaxin receptor 1;
DE   AltName: Full=Leucine-rich repeat-containing G-protein coupled receptor 7;
DE   AltName: Full=Relaxin family peptide receptor 1;
GN   Name=RXFP1; Synonyms=LGR7;
DR   GuidetoPHARMACOLOGY; 351; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0060427; P:lung connective tissue development; IEA:Ensembl.
DR   GO; GO:0060658; P:nipple morphogenesis; IEA:Ensembl.
DR   GO; GO:0007567; P:parturition; IEA:Ensembl.
//
ID   RXFP2_HUMAN             Reviewed;         754 AA.
AC   Q8WXD0; B1ALE9; Q3KU23;
DE   RecName: Full=Relaxin receptor 2;
DE   AltName: Full=G-protein coupled receptor 106;
DE   AltName: Full=G-protein coupled receptor affecting testicular descent;
DE   AltName: Full=Leucine-rich repeat-containing G-protein coupled receptor 8;
DE   AltName: Full=Relaxin family peptide receptor 2;
GN   Name=RXFP2; Synonyms=GPR106, GREAT, LGR8;
DR   GuidetoPHARMACOLOGY; 352; -.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0016500; F:protein-hormone receptor activity; IEA:Ensembl.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0001556; P:oocyte maturation; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IEA:Ensembl.
//
ID   RXRA_HUMAN              Reviewed;         462 AA.
AC   P19793; Q2NL52; Q2V504;
DE   RecName: Full=Retinoic acid receptor RXR-alpha;
DE   AltName: Full=Nuclear receptor subfamily 2 group B member 1;
DE   AltName: Full=Retinoid X receptor alpha;
GN   Name=RXRA; Synonyms=NR2B1;
DR   GuidetoPHARMACOLOGY; 610; -.
DR   GO; GO:0004886; F:9-cis retinoic acid receptor activity; TAS:ProtInc.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0003708; F:retinoic acid receptor activity; TAS:BHF-UCL.
DR   GO; GO:0044323; F:retinoic acid-responsive element binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0042809; F:vitamin D receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:BHF-UCL.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0035357; P:peroxisome proliferator activated receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0060528; P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:ProtInc.
//
ID   RXRB_HUMAN              Reviewed;         533 AA.
AC   P28702; P28703; Q59G65; Q5JP92; Q5STQ1;
DE   RecName: Full=Retinoic acid receptor RXR-beta;
DE   AltName: Full=Nuclear receptor subfamily 2 group B member 2;
DE   AltName: Full=Retinoid X receptor beta;
GN   Name=RXRB; Synonyms=NR2B2;
DR   GuidetoPHARMACOLOGY; 611; -.
DR   GO; GO:0004886; F:9-cis retinoic acid receptor activity; TAS:ProtInc.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0055012; P:ventricular cardiac muscle cell differentiation; IEA:Ensembl.
//
ID   RXRG_HUMAN              Reviewed;         463 AA.
AC   P48443; A6NIP1; Q6IBU7;
DE   RecName: Full=Retinoic acid receptor RXR-gamma;
DE   AltName: Full=Nuclear receptor subfamily 2 group B member 3;
DE   AltName: Full=Retinoid X receptor gamma;
GN   Name=RXRG; Synonyms=NR2B3;
DR   GuidetoPHARMACOLOGY; 612; -.
DR   GO; GO:0004886; F:9-cis retinoic acid receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   RX_HUMAN                Reviewed;         346 AA.
AC   Q9Y2V3; Q86V11;
DE   RecName: Full=Retinal homeobox protein Rx;
DE   AltName: Full=Retina and anterior neural fold homeobox protein;
GN   Name=RAX; Synonyms=RX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0021854; P:hypothalamus development; IEA:Ensembl.
DR   GO; GO:0060173; P:limb development; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   RYBP_HUMAN              Reviewed;         228 AA.
AC   Q8N488; Q9P2W5; Q9UMW4;
DE   RecName: Full=RING1 and YY1-binding protein;
DE   AltName: Full=Apoptin-associating protein 1;
DE            Short=APAP-1;
DE   AltName: Full=Death effector domain-associated factor;
DE            Short=DED-associated factor;
DE   AltName: Full=YY1 and E4TF1-associated factor 1;
GN   Name=RYBP; Synonyms=DEDAF, YEAF1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   RYK_HUMAN               Reviewed;         604 AA.
AC   P34925; Q04696;
DE   RecName: Full=Tyrosine-protein kinase RYK;
DE            EC=2.7.10.1;
DE   Flags: Precursor;
GN   Name=RYK; Synonyms=JTK5A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0071679; P:commissural neuron axon guidance; IEA:Ensembl.
DR   GO; GO:0022038; P:corpus callosum development; ISS:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; IEA:Ensembl.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   RYR1_HUMAN              Reviewed;        5038 AA.
AC   P21817; Q16314; Q16368; Q9NPK1; Q9P1U4;
DE   RecName: Full=Ryanodine receptor 1;
DE            Short=RYR-1;
DE            Short=RyR1;
DE   AltName: Full=Skeletal muscle calcium release channel;
DE   AltName: Full=Skeletal muscle ryanodine receptor;
DE   AltName: Full=Skeletal muscle-type ryanodine receptor;
DE   AltName: Full=Type 1 ryanodine receptor;
GN   Name=RYR1; Synonyms=RYDR;
DR   GuidetoPHARMACOLOGY; 747; -.
DR   GO; GO:0005262; F:calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0015278; F:calcium-release channel activity; TAS:ProtInc.
DR   GO; GO:0005516; F:calmodulin binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; ISS:BHF-UCL.
DR   GO; GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; ISS:UniProtKB.
DR   GO; GO:0043931; P:ossification involved in bone maturation; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:BHF-UCL.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0031000; P:response to caffeine; ISS:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0048741; P:skeletal muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0043588; P:skin development; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   RYR2_HUMAN              Reviewed;        4967 AA.
AC   Q92736; Q15411; Q546N8; Q5T3P2;
DE   RecName: Full=Ryanodine receptor 2;
DE            Short=RYR-2;
DE            Short=RyR2;
DE            Short=hRYR-2;
DE   AltName: Full=Cardiac muscle ryanodine receptor;
DE   AltName: Full=Cardiac muscle ryanodine receptor-calcium release channel;
DE   AltName: Full=Type 2 ryanodine receptor;
GN   Name=RYR2;
DR   GuidetoPHARMACOLOGY; 748; -.
DR   GO; GO:0005262; F:calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048763; F:calcium-induced calcium release activity; IDA:BHF-UCL.
DR   GO; GO:0015278; F:calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; IMP:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0005218; F:intracellular ligand-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IDA:BHF-UCL.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IDA:BHF-UCL.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:0043924; F:suramin binding; IMP:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0006816; P:calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; IDA:BHF-UCL.
DR   GO; GO:0019722; P:calcium-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IDA:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0003300; P:cardiac muscle hypertrophy; ISS:BHF-UCL.
DR   GO; GO:0086064; P:cell communication by electrical coupling involved in cardiac conduction; IC:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; TAS:BHF-UCL.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0005513; P:detection of calcium ion; IDA:BHF-UCL.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072599; P:establishment of protein localization to endoplasmic reticulum; IDA:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0003220; P:left ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:1901896; P:positive regulation of calcium-transporting ATPase activity; IDA:BHF-UCL.
DR   GO; GO:0010460; P:positive regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0086094; P:positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0051284; P:positive regulation of sequestering of calcium ion; IDA:BHF-UCL.
DR   GO; GO:0086029; P:Purkinje myocyte to ventricular cardiac muscle cell signaling; ISS:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; ISS:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IMP:BHF-UCL.
DR   GO; GO:0031000; P:response to caffeine; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; ISS:BHF-UCL.
DR   GO; GO:0051775; P:response to redox state; IDA:BHF-UCL.
DR   GO; GO:0070296; P:sarcoplasmic reticulum calcium ion transport; TAS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0097050; P:type B pancreatic cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; ISS:BHF-UCL.
//
ID   RYR3_HUMAN              Reviewed;        4870 AA.
AC   Q15413; O15175; Q15412;
DE   RecName: Full=Ryanodine receptor 3;
DE            Short=RYR-3;
DE            Short=RyR3;
DE   AltName: Full=Brain ryanodine receptor-calcium release channel;
DE   AltName: Full=Brain-type ryanodine receptor;
DE   AltName: Full=Type 3 ryanodine receptor;
GN   Name=RYR3; Synonyms=HBRR;
DR   GuidetoPHARMACOLOGY; 749; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048763; F:calcium-induced calcium release activity; IEA:Ensembl.
DR   GO; GO:0015278; F:calcium-release channel activity; IMP:UniProtKB.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; ISS:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0071318; P:cellular response to ATP; ISS:UniProtKB.
DR   GO; GO:0071313; P:cellular response to caffeine; ISS:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
DR   GO; GO:0071286; P:cellular response to magnesium ion; ISS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051481; P:negative regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
DR   GO; GO:0006941; P:striated muscle contraction; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S100B_HUMAN             Reviewed;          92 AA.
AC   P04271; D3DSN6;
DE   RecName: Full=Protein S100-B;
DE   AltName: Full=S-100 protein beta chain;
DE   AltName: Full=S-100 protein subunit beta;
DE   AltName: Full=S100 calcium-binding protein B;
GN   Name=S100B;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; IPI:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0048156; F:tau protein binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0048708; P:astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; ISS:UniProtKB.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:2001015; P:negative regulation of skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0051597; P:response to methylmercury; IEA:Ensembl.
//
ID   S100G_HUMAN             Reviewed;          79 AA.
AC   P29377; Q5JS49;
DE   RecName: Full=Protein S100-G;
DE   AltName: Full=Calbindin-D9k;
DE   AltName: Full=S100 calcium-binding protein G;
DE   AltName: Full=Vitamin D-dependent calcium-binding protein, intestinal;
DE            Short=CABP;
GN   Name=S100G; Synonyms=CABP9K, CALB3, S100D;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005499; F:vitamin D binding; IEA:UniProtKB-KW.
//
ID   S100P_HUMAN             Reviewed;          95 AA.
AC   P25815; Q5J7W2;
DE   RecName: Full=Protein S100-P;
DE   AltName: Full=Migration-inducing gene 9 protein;
DE            Short=MIG9;
DE   AltName: Full=Protein S100-E;
DE   AltName: Full=S100 calcium-binding protein P;
GN   Name=S100P; Synonyms=S100E;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:HGNC.
DR   GO; GO:0000287; F:magnesium ion binding; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IEP:UniProtKB.
//
ID   S100Z_HUMAN             Reviewed;          99 AA.
AC   Q8WXG8;
DE   RecName: Full=Protein S100-Z;
DE   AltName: Full=S100 calcium-binding protein Z;
GN   Name=S100Z;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   S10A1_HUMAN             Reviewed;          94 AA.
AC   P23297; B2R5D9; Q5T7Y3;
DE   RecName: Full=Protein S100-A1;
DE   AltName: Full=S-100 protein alpha chain;
DE   AltName: Full=S-100 protein subunit alpha;
DE   AltName: Full=S100 calcium-binding protein A1;
GN   Name=S100A1; Synonyms=S100A;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:1901387; P:positive regulation of voltage-gated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; NAS:UniProtKB.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   S10A2_HUMAN             Reviewed;          98 AA.
AC   P29034; O00266; Q3KRB9; Q5RHS8; Q9BU83;
DE   RecName: Full=Protein S100-A2;
DE   AltName: Full=CAN19;
DE   AltName: Full=Protein S-100L;
DE   AltName: Full=S100 calcium-binding protein A2;
GN   Name=S100A2; Synonyms=S100L;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:UniProtKB.
//
ID   S10A3_HUMAN             Reviewed;         101 AA.
AC   P33764; D3DV51; Q6FGE4;
DE   RecName: Full=Protein S100-A3;
DE   AltName: Full=Protein S-100E;
DE   AltName: Full=S100 calcium-binding protein A3;
GN   Name=S100A3; Synonyms=S100E;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   S10A4_HUMAN             Reviewed;         101 AA.
AC   P26447; A8K7R8; D3DV46; Q6ICP8;
DE   RecName: Full=Protein S100-A4;
DE   AltName: Full=Calvasculin;
DE   AltName: Full=Metastasin;
DE   AltName: Full=Placental calcium-binding protein;
DE   AltName: Full=Protein Mts1;
DE   AltName: Full=S100 calcium-binding protein A4;
GN   Name=S100A4; Synonyms=CAPL, MTS1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; IPI:UniProtKB.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; TAS:HGNC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
//
ID   S10A5_HUMAN             Reviewed;          92 AA.
AC   P33763; Q5RHS3;
DE   RecName: Full=Protein S100-A5;
DE   AltName: Full=Protein S-100D;
DE   AltName: Full=S100 calcium-binding protein A5;
GN   Name=S100A5; Synonyms=S100D;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
//
ID   S10A6_HUMAN             Reviewed;          90 AA.
AC   P06703; D3DV39; Q5RHS4;
DE   RecName: Full=Protein S100-A6;
DE   AltName: Full=Calcyclin;
DE   AltName: Full=Growth factor-inducible protein 2A9;
DE   AltName: Full=MLN 4;
DE   AltName: Full=Prolactin receptor-associated protein;
DE            Short=PRA;
DE   AltName: Full=S100 calcium-binding protein A6;
GN   Name=S100A6; Synonyms=CACY;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0015075; F:ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0005523; F:tropomyosin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; NAS:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   S10A7_HUMAN             Reviewed;         101 AA.
AC   P31151; Q5SY67; Q6FGE3; Q9H1E2;
DE   RecName: Full=Protein S100-A7;
DE   AltName: Full=Psoriasin;
DE   AltName: Full=S100 calcium-binding protein A7;
GN   Name=S100A7; Synonyms=PSOR1, S100A7C;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IMP:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0071624; P:positive regulation of granulocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
DR   GO; GO:0051238; P:sequestering of metal ion; IDA:UniProtKB.
//
ID   S10A8_HUMAN             Reviewed;          93 AA.
AC   P05109; A8K5L3; D3DV37; Q5SY70; Q9UC84; Q9UC92; Q9UCJ0; Q9UCM6;
DE   RecName: Full=Protein S100-A8;
DE   AltName: Full=Calgranulin-A;
DE   AltName: Full=Calprotectin L1L subunit;
DE   AltName: Full=Cystic fibrosis antigen;
DE            Short=CFAG;
DE   AltName: Full=Leukocyte L1 complex light chain;
DE   AltName: Full=Migration inhibitory factor-related protein 8;
DE            Short=MRP-8;
DE            Short=p8;
DE   AltName: Full=S100 calcium-binding protein A8;
DE   AltName: Full=Urinary stone protein band A;
DE   Contains:
DE     RecName: Full=Protein S100-A8, N-terminally processed;
GN   Name=S100A8; Synonyms=CAGA, CFAG, MRP8;
DR   GO; GO:0050544; F:arachidonic acid binding; TAS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050786; F:RAGE receptor binding; TAS:UniProtKB.
DR   GO; GO:0035662; F:Toll-like receptor 4 binding; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0006914; P:autophagy; IDA:UniProtKB.
DR   GO; GO:0032602; P:chemokine production; TAS:UniProtKB.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0001816; P:cytokine production; TAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0050832; P:defense response to fungus; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0002523; P:leukocyte migration involved in inflammatory response; IDA:UniProtKB.
DR   GO; GO:0070488; P:neutrophil aggregation; IDA:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0032119; P:sequestering of zinc ion; TAS:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   S10A9_HUMAN             Reviewed;         114 AA.
AC   P06702; D3DV36; Q6FGA1; Q9NYM0; Q9UCJ1;
DE   RecName: Full=Protein S100-A9;
DE   AltName: Full=Calgranulin-B;
DE   AltName: Full=Calprotectin L1H subunit;
DE   AltName: Full=Leukocyte L1 complex heavy chain;
DE   AltName: Full=Migration inhibitory factor-related protein 14;
DE            Short=MRP-14;
DE            Short=p14;
DE   AltName: Full=S100 calcium-binding protein A9;
GN   Name=S100A9; Synonyms=CAGB, CFAG, MRP14;
DR   GO; GO:0016209; F:antioxidant activity; IEA:UniProtKB-KW.
DR   GO; GO:0050544; F:arachidonic acid binding; TAS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050786; F:RAGE receptor binding; TAS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0035662; F:Toll-like receptor 4 binding; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IDA:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0032602; P:chemokine production; TAS:UniProtKB.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0001816; P:cytokine production; TAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0050832; P:defense response to fungus; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0002523; P:leukocyte migration involved in inflammatory response; IDA:UniProtKB.
DR   GO; GO:0070488; P:neutrophil aggregation; IDA:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.
DR   GO; GO:0045113; P:regulation of integrin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0032119; P:sequestering of zinc ion; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   S10AA_HUMAN             Reviewed;          97 AA.
AC   P60903; A8K4V8; P08206; Q5T1C5;
DE   RecName: Full=Protein S100-A10;
DE   AltName: Full=Calpactin I light chain;
DE   AltName: Full=Calpactin-1 light chain;
DE   AltName: Full=Cellular ligand of annexin II;
DE   AltName: Full=S100 calcium-binding protein A10;
DE   AltName: Full=p10 protein;
DE   AltName: Full=p11;
GN   Name=S100A10; Synonyms=ANX2LG, CAL1L, CLP11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0044325; F:ion channel binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0071229; P:cellular response to acid; IEA:Ensembl.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IDA:UniProt.
DR   GO; GO:0006900; P:membrane budding; IDA:UniProt.
DR   GO; GO:0001765; P:membrane raft assembly; IDA:UniProt.
DR   GO; GO:0051099; P:positive regulation of binding; IEA:Ensembl.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProt.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IMP:UniProt.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProt.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IMP:UniProt.
DR   GO; GO:0051290; P:protein heterotetramerization; IDA:UniProt.
//
ID   S10AB_HUMAN             Reviewed;         105 AA.
AC   P31949; Q5VTK0;
DE   RecName: Full=Protein S100-A11;
DE   AltName: Full=Calgizzarin;
DE   AltName: Full=Metastatic lymph node gene 70 protein;
DE            Short=MLN 70;
DE   AltName: Full=Protein S100-C;
DE   AltName: Full=S100 calcium-binding protein A11;
DE   Contains:
DE     RecName: Full=Protein S100-A11, N-terminally processed;
GN   Name=S100A11; Synonyms=MLN70, S100C;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0044548; F:S100 protein binding; IPI:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0008156; P:negative regulation of DNA replication; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   S10AC_HUMAN             Reviewed;          92 AA.
AC   P80511; P83219; Q5SY66; Q7M4R1;
DE   RecName: Full=Protein S100-A12;
DE   AltName: Full=CGRP;
DE   AltName: Full=Calcium-binding protein in amniotic fluid 1;
DE            Short=CAAF1;
DE   AltName: Full=Calgranulin-C;
DE            Short=CAGC;
DE   AltName: Full=Extracellular newly identified RAGE-binding protein;
DE            Short=EN-RAGE;
DE   AltName: Full=Migration inhibitory factor-related protein 6;
DE            Short=MRP-6;
DE            Short=p6;
DE   AltName: Full=Neutrophil S100 protein;
DE   AltName: Full=S100 calcium-binding protein A12;
DE   Contains:
DE     RecName: Full=Calcitermin;
GN   Name=S100A12;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0050663; P:cytokine secretion; TAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0031640; P:killing of cells of other organism; IEA:UniProtKB-KW.
DR   GO; GO:0045576; P:mast cell activation; TAS:UniProtKB.
DR   GO; GO:0002548; P:monocyte chemotaxis; TAS:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; TAS:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; TAS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   S10AD_HUMAN             Reviewed;          98 AA.
AC   Q99584; Q52PI9; Q6FGF8;
DE   RecName: Full=Protein S100-A13;
DE   AltName: Full=S100 calcium-binding protein A13;
GN   Name=S100A13;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0050786; F:RAGE receptor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0050663; P:cytokine secretion; IMP:UniProtKB.
DR   GO; GO:0050703; P:interleukin-1 alpha secretion; IDA:UniProtKB.
DR   GO; GO:0043303; P:mast cell degranulation; NAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
//
ID   S10AE_HUMAN             Reviewed;         104 AA.
AC   Q9HCY8; Q5RHT0;
DE   RecName: Full=Protein S100-A14;
DE   AltName: Full=S100 calcium-binding protein A14;
DE            Short=S114;
GN   Name=S100A14; Synonyms=S100A15;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0042379; F:chemokine receptor binding; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0055074; P:calcium ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEP:UniProtKB.
DR   GO; GO:0071624; P:positive regulation of granulocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:UniProtKB.
//
ID   S10AG_HUMAN             Reviewed;         103 AA.
AC   Q96FQ6; A8K439; D3DV52; Q5RHS6;
DE   RecName: Full=Protein S100-A16;
DE   AltName: Full=Aging-associated gene 13 protein;
DE   AltName: Full=Protein S100-F;
DE   AltName: Full=S100 calcium-binding protein A16;
GN   Name=S100A16; Synonyms=S100F; ORFNames=AAG13;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
//
ID   S11IP_HUMAN             Reviewed;        1099 AA.
AC   Q8N1F8; Q8NAW9; Q8WXE4; Q96CN3; Q96PY9;
DE   RecName: Full=Serine/threonine-protein kinase 11-interacting protein;
DE   AltName: Full=LKB1-interacting protein 1;
GN   Name=STK11IP; Synonyms=KIAA1898, LIP1, LKB1IP, STK11IP1;
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
//
ID   S12A1_HUMAN             Reviewed;        1099 AA.
AC   Q13621; A8JYA2; E9PDW4;
DE   RecName: Full=Solute carrier family 12 member 1;
DE   AltName: Full=Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2;
DE   AltName: Full=Kidney-specific Na-K-Cl symporter;
GN   Name=SLC12A1; Synonyms=NKCC2;
DR   GuidetoPHARMACOLOGY; 968; -.
DR   GO; GO:0008511; F:sodium:potassium:chloride symporter activity; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
DR   GO; GO:0034220; P:ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S12A2_HUMAN             Reviewed;        1212 AA.
AC   P55011; Q8N713; Q8WWH7;
DE   RecName: Full=Solute carrier family 12 member 2;
DE   AltName: Full=Basolateral Na-K-Cl symporter;
DE   AltName: Full=Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1;
GN   Name=SLC12A2; Synonyms=NKCC1;
DR   GuidetoPHARMACOLOGY; 969; -.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008511; F:sodium:potassium:chloride symporter activity; TAS:ProtInc.
DR   GO; GO:0072488; P:ammonium transmembrane transport; IDA:GOC.
DR   GO; GO:0015696; P:ammonium transport; IDA:UniProtKB.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0060763; P:mammary duct terminal end bud growth; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045795; P:positive regulation of cell volume; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0070634; P:transepithelial ammonium transport; IDA:UniProtKB.
DR   GO; GO:0030321; P:transepithelial chloride transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S12A3_HUMAN             Reviewed;        1021 AA.
AC   P55017; A8MSJ2; C9JNN9;
DE   RecName: Full=Solute carrier family 12 member 3;
DE   AltName: Full=Na-Cl cotransporter;
DE            Short=NCC;
DE   AltName: Full=Na-Cl symporter;
DE   AltName: Full=Thiazide-sensitive sodium-chloride cotransporter;
GN   Name=SLC12A3; Synonyms=TSC;
DR   GuidetoPHARMACOLOGY; 970; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015378; F:sodium:chloride symporter activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; ISS:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S12A4_HUMAN             Reviewed;        1085 AA.
AC   Q9UP95; B4DF69; B4DR04; B4DZ82; B7ZAV0; F5H066; F5H0S9; F5H3C0;
AC   O60632; O75893; Q13953; Q96LD5;
DE   RecName: Full=Solute carrier family 12 member 4;
DE   AltName: Full=Electroneutral potassium-chloride cotransporter 1;
DE   AltName: Full=Erythroid K-Cl cotransporter 1;
DE            Short=hKCC1;
GN   Name=SLC12A4; Synonyms=KCC1;
DR   GuidetoPHARMACOLOGY; 971; -.
DR   GO; GO:0015379; F:potassium:chloride symporter activity; TAS:ProtInc.
DR   GO; GO:0006884; P:cell volume homeostasis; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S12A5_HUMAN             Reviewed;        1139 AA.
AC   Q9H2X9; A2RTX2; Q5VZ41; Q9H4Z0; Q9ULP4;
DE   RecName: Full=Solute carrier family 12 member 5;
DE   AltName: Full=Electroneutral potassium-chloride cotransporter 2;
DE   AltName: Full=K-Cl cotransporter 2;
DE            Short=hKCC2;
DE   AltName: Full=Neuronal K-Cl cotransporter;
GN   Name=SLC12A5; Synonyms=KCC2, KIAA1176;
DR   GuidetoPHARMACOLOGY; 972; -.
DR   GO; GO:0015379; F:potassium:chloride symporter activity; NAS:UniProtKB.
DR   GO; GO:0006873; P:cellular ion homeostasis; NAS:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; NAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0040040; P:thermosensory behavior; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:UniProtKB.
//
ID   S12A6_HUMAN             Reviewed;        1150 AA.
AC   Q9UHW9; A0AV76; Q2VI00; Q7Z2E7; Q7Z4G5; Q8TDD4; Q9UFR2; Q9Y642;
AC   Q9Y665;
DE   RecName: Full=Solute carrier family 12 member 6;
DE   AltName: Full=Electroneutral potassium-chloride cotransporter 3;
DE   AltName: Full=K-Cl cotransporter 3;
GN   Name=SLC12A6; Synonyms=KCC3;
DR   GuidetoPHARMACOLOGY; 973; -.
DR   GO; GO:0015379; F:potassium:chloride symporter activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0071477; P:cellular hypotonic salinity response; IDA:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:GOC.
DR   GO; GO:0006811; P:ion transport; IDA:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S12A7_HUMAN             Reviewed;        1083 AA.
AC   Q9Y666; A6NDS8; Q4G0F3; Q96I81; Q9H7I3; Q9H7I7; Q9UFW2;
DE   RecName: Full=Solute carrier family 12 member 7;
DE   AltName: Full=Electroneutral potassium-chloride cotransporter 4;
DE   AltName: Full=K-Cl cotransporter 4;
GN   Name=SLC12A7; Synonyms=KCC4;
DR   GuidetoPHARMACOLOGY; 974; -.
DR   GO; GO:0015379; F:potassium:chloride symporter activity; TAS:ProtInc.
DR   GO; GO:0006884; P:cell volume homeostasis; IEA:Ensembl.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S12A8_HUMAN             Reviewed;         714 AA.
AC   A0AV02; C9JJJ2; Q68D04; Q6I9Z2; Q6P4C0; Q7Z3A6; Q86WK0; Q8NFX9;
AC   Q8WUI3; Q96RF9; Q9H5P9;
DE   RecName: Full=Solute carrier family 12 member 8;
DE   AltName: Full=Cation-chloride cotransporter 9;
GN   Name=SLC12A8; Synonyms=CCC9;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
//
ID   S12A9_HUMAN             Reviewed;         914 AA.
AC   Q9BXP2; B7Z740; D6W5X0; D6W5X2; F5H8C2; Q9BWL2; Q9BXP1; Q9BYI0;
AC   Q9NQR5;
DE   RecName: Full=Solute carrier family 12 member 9;
DE   AltName: Full=Cation-chloride cotransporter 6;
DE            Short=hCCC6;
DE   AltName: Full=Cation-chloride cotransporter-interacting protein 1;
DE            Short=CCC-interacting protein 1;
DE            Short=hCIP1;
DE   AltName: Full=Potassium-chloride transporter 9;
DE   AltName: Full=WO3.3;
GN   Name=SLC12A9; Synonyms=CCC6, CIP1;
DR   GO; GO:0015377; F:cation:chloride symporter activity; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0006821; P:chloride transport; TAS:GOC.
//
ID   S13A1_HUMAN             Reviewed;         595 AA.
AC   Q9BZW2; Q9H5Z0;
DE   RecName: Full=Solute carrier family 13 member 1;
DE   AltName: Full=Renal sodium/sulfate cotransporter;
DE            Short=Na(+)/sulfate cotransporter;
DE            Short=hNaSi-1;
GN   Name=SLC13A1; Synonyms=NAS1, NASI1;
DR   GO; GO:0015382; F:sodium:sulfate symporter activity; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S13A2_HUMAN             Reviewed;         592 AA.
AC   Q13183; B2RBI9; B4DPL1; E7ETH5; Q4VAR7;
DE   RecName: Full=Solute carrier family 13 member 2;
DE   AltName: Full=Na(+)/dicarboxylate cotransporter 1;
DE            Short=NaDC-1;
DE   AltName: Full=Renal sodium/dicarboxylate cotransporter;
GN   Name=SLC13A2; Synonyms=NADC1, SDCT1;
DR   GO; GO:0015361; F:low affinity sodium:dicarboxylate symporter activity; TAS:ProtInc.
DR   GO; GO:0006835; P:dicarboxylic acid transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S13A3_HUMAN             Reviewed;         602 AA.
AC   Q8WWT9; B4DIR8; E1P5U4; F6WI18; Q5JYC9; Q5JYD0; Q5JYD1; Q5TCQ2;
AC   Q8IVB1; Q8N8K4; Q96MM5; Q9BR25; Q9H1G1; Q9H3W4; Q9NQN5; Q9NS04;
DE   RecName: Full=Solute carrier family 13 member 3;
DE   AltName: Full=Na(+)/dicarboxylate cotransporter 3;
DE            Short=NaDC-3;
DE            Short=hNaDC3;
DE   AltName: Full=Sodium-dependent high-affinity dicarboxylate transporter 2;
GN   Name=SLC13A3; Synonyms=NADC3, SDCT2;
DR   GO; GO:0015362; F:high affinity sodium:dicarboxylate symporter activity; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S13A4_HUMAN             Reviewed;         626 AA.
AC   Q9UKG4; A4D1Q4; Q8N631;
DE   RecName: Full=Solute carrier family 13 member 4;
DE   AltName: Full=Na(+)/sulfate cotransporter SUT-1;
DE   AltName: Full=NaS2;
GN   Name=SLC13A4; Synonyms=SUT1;
DR   GO; GO:0015382; F:sodium:sulfate symporter activity; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0008272; P:sulfate transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S13A5_HUMAN             Reviewed;         568 AA.
AC   Q86YT5; B3KXR0; B7ZLB4; Q6ZMG1;
DE   RecName: Full=Solute carrier family 13 member 5;
DE   AltName: Full=Na(+)/citrate cotransporter;
DE            Short=NaCT;
DE   AltName: Full=Sodium-coupled citrate transporter;
DE   AltName: Full=Sodium-dependent citrate transporter;
GN   Name=SLC13A5; Synonyms=NACT;
DR   GO; GO:0015137; F:citrate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:Ensembl.
DR   GO; GO:0015141; F:succinate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S14L1_HUMAN             Reviewed;         715 AA.
AC   Q92503; A8K4E8; B4DDI5; D5G3K1; Q99780;
DE   RecName: Full=SEC14-like protein 1;
GN   Name=SEC14L1; Synonyms=SEC14L;
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   S14L2_HUMAN             Reviewed;         403 AA.
AC   O76054; B7Z8Q1; F5H3U4; Q53EQ2; Q6PD61; Q9ULN4;
DE   RecName: Full=SEC14-like protein 2;
DE   AltName: Full=Alpha-tocopherol-associated protein;
DE            Short=TAP;
DE            Short=hTAP;
DE   AltName: Full=Squalene transfer protein;
DE   AltName: Full=Supernatant protein factor;
DE            Short=SPF;
GN   Name=SEC14L2; Synonyms=C22orf6, KIAA1186, KIAA1658;
DR   GO; GO:0005543; F:phospholipid binding; NAS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008431; F:vitamin E binding; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0045540; P:regulation of cholesterol biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   S14L3_HUMAN             Reviewed;         400 AA.
AC   Q9UDX4; E7EN74; E9PE57; Q495V8; Q495W0; Q495W1;
DE   RecName: Full=SEC14-like protein 3;
DE   AltName: Full=Tocopherol-associated protein 2;
GN   Name=SEC14L3; Synonyms=TAP2;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   S14L5_HUMAN             Reviewed;         696 AA.
AC   O43304;
DE   RecName: Full=SEC14-like protein 5;
GN   Name=SEC14L5; Synonyms=KIAA0420;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   S14L4_HUMAN             Reviewed;         406 AA.
AC   Q9UDX3; A5D6W7; A6NCV4;
DE   RecName: Full=SEC14-like protein 4;
DE   AltName: Full=Tocopherol-associated protein 3;
GN   Name=SEC14L4; Synonyms=TAP3;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   S14L6_HUMAN             Reviewed;         397 AA.
AC   B5MCN3;
DE   RecName: Full=Putative SEC14-like protein 6;
GN   Name=SEC14L6;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   S15A1_HUMAN             Reviewed;         708 AA.
AC   P46059; Q5VW82;
DE   RecName: Full=Solute carrier family 15 member 1;
DE   AltName: Full=Intestinal H(+)/peptide cotransporter;
DE   AltName: Full=Oligopeptide transporter, small intestine isoform;
DE   AltName: Full=Peptide transporter 1;
GN   Name=SLC15A1; Synonyms=PEPT1;
DR   GuidetoPHARMACOLOGY; 984; -.
DR   GO; GO:0015333; F:peptide:proton symporter activity; TAS:ProtInc.
DR   GO; GO:0005427; F:proton-dependent oligopeptide secondary active transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0015992; P:proton transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S15A2_HUMAN             Reviewed;         729 AA.
AC   Q16348; A8K1A5; B4E2A7;
DE   RecName: Full=Solute carrier family 15 member 2;
DE   AltName: Full=Kidney H(+)/peptide cotransporter;
DE   AltName: Full=Oligopeptide transporter, kidney isoform;
DE   AltName: Full=Peptide transporter 2;
GN   Name=SLC15A2; Synonyms=PEPT2;
DR   GuidetoPHARMACOLOGY; 985; -.
DR   GO; GO:0042895; F:antibiotic transporter activity; IEA:Ensembl.
DR   GO; GO:0042936; F:dipeptide transporter activity; IEA:Ensembl.
DR   GO; GO:0015334; F:high affinity oligopeptide transporter activity; IEA:Ensembl.
DR   GO; GO:0015333; F:peptide:proton symporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015893; P:drug transport; NAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0015992; P:proton transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S15A3_HUMAN             Reviewed;         581 AA.
AC   Q8IY34; Q9P2X9;
DE   RecName: Full=Solute carrier family 15 member 3;
DE   AltName: Full=Osteoclast transporter;
DE   AltName: Full=Peptide transporter 3;
DE   AltName: Full=Peptide/histidine transporter 2;
GN   Name=SLC15A3; Synonyms=OCTP, PHT2, PTR3;
DR   GuidetoPHARMACOLOGY; 986; -.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S15A4_HUMAN             Reviewed;         577 AA.
AC   Q8N697; A6H8Y9; B3KTK1; Q71M34; Q7Z5F8; Q8TAH0;
DE   RecName: Full=Solute carrier family 15 member 4;
DE   AltName: Full=Peptide transporter 4;
DE   AltName: Full=Peptide/histidine transporter 1;
DE            Short=hPHT1;
GN   Name=SLC15A4; Synonyms=PHT1, PTR4; ORFNames=FP12591;
DR   GuidetoPHARMACOLOGY; 987; -.
DR   GO; GO:0005290; F:L-histidine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006857; P:oligopeptide transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S15A5_HUMAN             Reviewed;         579 AA.
AC   A6NIM6;
DE   RecName: Full=Solute carrier family 15 member 5;
GN   Name=SLC15A5;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   S17A4_HUMAN             Reviewed;         497 AA.
AC   Q9Y2C5; B4DDV9; E7EPE8; E7EU17; Q32MB7; Q32MB8;
DE   RecName: Full=Probable small intestine urate exporter;
DE   AltName: Full=Solute carrier family 17 member 4;
GN   Name=SLC17A4;
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; TAS:ProtInc.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   S17A5_HUMAN             Reviewed;         495 AA.
AC   Q9NRA2; Q5SZ76; Q8NBR5; Q9UGH0;
DE   RecName: Full=Sialin;
DE   AltName: Full=H(+)/nitrate cotransporter;
DE   AltName: Full=H(+)/sialic acid cotransporter;
DE            Short=AST;
DE   AltName: Full=Membrane glycoprotein HP59;
DE   AltName: Full=Solute carrier family 17 member 5;
DE   AltName: Full=Vesicular H(+)/Aspartate-glutamate cotransporter;
GN   Name=SLC17A5;
DR   GO; GO:0015136; F:sialic acid transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0005351; F:sugar:proton symporter activity; TAS:ProtInc.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006820; P:anion transport; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:GOC.
DR   GO; GO:0015739; P:sialic acid transport; IDA:MGI.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S17A9_HUMAN             Reviewed;         436 AA.
AC   Q9BYT1; B3KTF2; Q5W198; Q8TB07; Q8TBP4; Q8TEL5; Q9BYT0; Q9BYT2;
DE   RecName: Full=Solute carrier family 17 member 9;
GN   Name=SLC17A9; Synonyms=C20orf59;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S18L2_HUMAN             Reviewed;          77 AA.
AC   Q9UHA2; B2R5L1;
DE   RecName: Full=SS18-like protein 2;
DE   AltName: Full=SYT homolog 2;
GN   Name=SS18L2;
//
ID   S18B1_HUMAN             Reviewed;         456 AA.
AC   Q6NT16; A8K1K3; B3KW77; Q6ISF2;
DE   RecName: Full=MFS-type transporter SLC18B1;
DE   AltName: Full=Solute carrier family 18 member B1;
GN   Name=SLC18B1; Synonyms=C6orf192;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S19A1_HUMAN             Reviewed;         591 AA.
AC   P41440; B2R7U8; B7Z8C3; E9PFY4; O00553; O60227; Q13026; Q9BTX8;
DE   RecName: Full=Folate transporter 1;
DE            Short=FOLT;
DE   AltName: Full=Intestinal folate carrier 1;
DE            Short=IFC-1;
DE   AltName: Full=Placental folate transporter;
DE   AltName: Full=Reduced folate carrier protein;
DE            Short=RFC;
DE   AltName: Full=Solute carrier family 19 member 1;
GN   Name=SLC19A1; Synonyms=FLOT1, RFC1;
DR   GuidetoPHARMACOLOGY; 1014; -.
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0008517; F:folic acid transporter activity; TAS:ProtInc.
DR   GO; GO:0015350; F:methotrexate transporter activity; TAS:ProtInc.
DR   GO; GO:0046655; P:folic acid metabolic process; TAS:Reactome.
DR   GO; GO:0015884; P:folic acid transport; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   S19A2_HUMAN             Reviewed;         497 AA.
AC   O60779; B2R9H0; B4E1X4; Q8WV87; Q9UBL7; Q9UKJ2; Q9UN31; Q9UN43;
DE   RecName: Full=Thiamine transporter 1;
DE            Short=ThTr-1;
DE            Short=ThTr1;
DE   AltName: Full=Solute carrier family 19 member 2;
DE   AltName: Full=Thiamine carrier 1;
DE            Short=TC1;
GN   Name=SLC19A2; Synonyms=THT1, TRMA;
DR   GuidetoPHARMACOLOGY; 1015; -.
DR   GO; GO:0008517; F:folic acid transporter activity; NAS:UniProtKB.
DR   GO; GO:0015234; F:thiamine transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0015403; F:thiamine uptake transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0015884; P:folic acid transport; NAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0071934; P:thiamine transmembrane transport; ISS:GOC.
DR   GO; GO:0015888; P:thiamine transport; NAS:UniProtKB.
DR   GO; GO:0042723; P:thiamine-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   S19A3_HUMAN             Reviewed;         496 AA.
AC   Q9BZV2;
DE   RecName: Full=Thiamine transporter 2;
DE            Short=ThTr-2;
DE            Short=ThTr2;
DE   AltName: Full=Solute carrier family 19 member 3;
GN   Name=SLC19A3;
DR   GuidetoPHARMACOLOGY; 1016; -.
DR   GO; GO:0015403; F:thiamine uptake transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0071934; P:thiamine transmembrane transport; ISS:GOC.
DR   GO; GO:0042723; P:thiamine-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   S1A7A_HUMAN             Reviewed;         101 AA.
AC   Q86SG5; D3DV38; Q5SY69;
DE   RecName: Full=Protein S100-A7A;
DE   AltName: Full=S100 calcium-binding protein A15;
DE   AltName: Full=S100 calcium-binding protein A7-like 1;
DE   AltName: Full=S100 calcium-binding protein A7A;
GN   Name=S100A7A; Synonyms=S100A15, S100A7L1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0043621; F:protein self-association; IPI:MGI.
//
ID   S1A7B_HUMAN             Reviewed;         101 AA.
AC   Q5SY68;
DE   RecName: Full=Protein S100-A7-like 2;
DE   AltName: Full=S100 calcium-binding protein A7-like 2;
GN   Name=S100A7L2; Synonyms=S100A7B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   S1PBP_HUMAN             Reviewed;         408 AA.
AC   Q96BU1; B3KR04; D3DPQ5; Q5HYH3; Q9H997;
DE   RecName: Full=S100P-binding protein;
DE   AltName: Full=S100P-binding protein Riken;
GN   Name=S100PBP; Synonyms=S100PBPR;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:HGNC.
//
ID   S1PR1_HUMAN             Reviewed;         382 AA.
AC   P21453; D3DT66; Q9BYY4; Q9NYN8;
DE   RecName: Full=Sphingosine 1-phosphate receptor 1;
DE            Short=S1P receptor 1;
DE            Short=S1P1;
DE   AltName: Full=Endothelial differentiation G-protein coupled receptor 1;
DE   AltName: Full=Sphingosine 1-phosphate receptor Edg-1;
DE            Short=S1P receptor Edg-1;
DE   AltName: CD_antigen=CD363;
GN   Name=S1PR1; Synonyms=CHEDG1, EDG1;
DR   GuidetoPHARMACOLOGY; 275; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0046625; F:sphingolipid binding; IEA:Ensembl.
DR   GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IDA:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001955; P:blood vessel maturation; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0003245; P:cardiac muscle tissue growth involved in heart morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; ISS:UniProtKB.
DR   GO; GO:0045446; P:endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0061384; P:heart trabecula morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030500; P:regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:0045124; P:regulation of bone resorption; ISS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0003376; P:sphingosine-1-phosphate signaling pathway; IDA:UniProtKB.
DR   GO; GO:0072678; P:T cell migration; ISS:UniProtKB.
DR   GO; GO:0019226; P:transmission of nerve impulse; IEA:Ensembl.
//
ID   S1PR2_HUMAN             Reviewed;         353 AA.
AC   O95136; Q86UN8;
DE   RecName: Full=Sphingosine 1-phosphate receptor 2;
DE            Short=S1P receptor 2;
DE            Short=S1P2;
DE   AltName: Full=Endothelial differentiation G-protein coupled receptor 5;
DE   AltName: Full=Sphingosine 1-phosphate receptor Edg-5;
DE            Short=S1P receptor Edg-5;
GN   Name=S1PR2; Synonyms=EDG5;
DR   GuidetoPHARMACOLOGY; 276; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0090394; P:negative regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   S1PR3_HUMAN             Reviewed;         378 AA.
AC   Q99500; Q5SQD8; Q7Z5I2;
DE   RecName: Full=Sphingosine 1-phosphate receptor 3;
DE            Short=S1P receptor 3;
DE            Short=S1P3;
DE   AltName: Full=Endothelial differentiation G-protein coupled receptor 3;
DE   AltName: Full=Sphingosine 1-phosphate receptor Edg-3;
DE            Short=S1P receptor Edg-3;
GN   Name=S1PR3; Synonyms=EDG3;
DR   GuidetoPHARMACOLOGY; 277; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:InterPro.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0032651; P:regulation of interleukin-1 beta production; IEA:Ensembl.
//
ID   S1PR4_HUMAN             Reviewed;         384 AA.
AC   O95977; D6W612;
DE   RecName: Full=Sphingosine 1-phosphate receptor 4;
DE            Short=S1P receptor 4;
DE            Short=S1P4;
DE   AltName: Full=Endothelial differentiation G-protein coupled receptor 6;
DE   AltName: Full=Sphingosine 1-phosphate receptor Edg-6;
DE            Short=S1P receptor Edg-6;
GN   Name=S1PR4; Synonyms=EDG6;
DR   GuidetoPHARMACOLOGY; 278; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:InterPro.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
//
ID   S1PR5_HUMAN             Reviewed;         398 AA.
AC   Q9H228; Q6NW11;
DE   RecName: Full=Sphingosine 1-phosphate receptor 5;
DE            Short=S1P receptor 5;
DE            Short=S1P5;
DE   AltName: Full=Endothelial differentiation G-protein-coupled receptor 8;
DE   AltName: Full=Sphingosine 1-phosphate receptor Edg-8;
DE            Short=S1P receptor Edg-8;
GN   Name=S1PR5; Synonyms=EDG8;
DR   GuidetoPHARMACOLOGY; 279; -.
DR   GO; GO:0038036; F:sphingosine-1-phosphate receptor activity; IEA:InterPro.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
//
ID   S20A1_HUMAN             Reviewed;         679 AA.
AC   Q8WUM9; Q08344; Q6DHX8; Q9UQ82;
DE   RecName: Full=Sodium-dependent phosphate transporter 1;
DE   AltName: Full=Gibbon ape leukemia virus receptor 1;
DE            Short=GLVR-1;
DE   AltName: Full=Leukemia virus receptor 1 homolog;
DE   AltName: Full=Phosphate transporter 1;
DE            Short=PiT-1;
DE   AltName: Full=Solute carrier family 20 member 1;
GN   Name=SLC20A1; Synonyms=GLVR1, PIT1;
DR   GO; GO:0005316; F:high affinity inorganic phosphate:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S20A2_HUMAN             Reviewed;         652 AA.
AC   Q08357;
DE   RecName: Full=Sodium-dependent phosphate transporter 2;
DE   AltName: Full=Gibbon ape leukemia virus receptor 2;
DE            Short=GLVR-2;
DE   AltName: Full=Phosphate transporter 2;
DE            Short=PiT-2;
DE            Short=Pit2;
DE            Short=hPit2;
DE   AltName: Full=Solute carrier family 20 member 2;
GN   Name=SLC20A2; Synonyms=GLVR2, PIT2;
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; TAS:ProtInc.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; TAS:GOC.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   S22A1_HUMAN             Reviewed;         554 AA.
AC   O15245; A6NFF3; A8K1H2; C9JSU6; O15395; Q9NQD4;
DE   RecName: Full=Solute carrier family 22 member 1;
DE   AltName: Full=Organic cation transporter 1;
DE            Short=hOCT1;
GN   Name=SLC22A1; Synonyms=OCT1;
DR   GO; GO:0005277; F:acetylcholine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005329; F:dopamine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005333; F:norepinephrine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015651; F:quaternary ammonium group transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0008513; F:secondary active organic cation transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015872; P:dopamine transport; IEA:Ensembl.
DR   GO; GO:0006855; P:drug transmembrane transport; TAS:Reactome.
DR   GO; GO:0048241; P:epinephrine transport; IEA:Ensembl.
DR   GO; GO:0010248; P:establishment or maintenance of transmembrane electrochemical gradient; IEA:Ensembl.
DR   GO; GO:0015874; P:norepinephrine transport; IEA:Ensembl.
DR   GO; GO:0015695; P:organic cation transport; TAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A2_HUMAN             Reviewed;         555 AA.
AC   O15244; Q5T7Q6; Q6PIQ8; Q8NG62; Q9NQB9;
DE   RecName: Full=Solute carrier family 22 member 2;
DE   AltName: Full=Organic cation transporter 2;
DE            Short=hOCT2;
GN   Name=SLC22A2; Synonyms=OCT2;
DR   GO; GO:0015220; F:choline transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0015651; F:quaternary ammonium group transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005496; F:steroid binding; IEA:Ensembl.
DR   GO; GO:0007589; P:body fluid secretion; TAS:ProtInc.
DR   GO; GO:0006855; P:drug transmembrane transport; TAS:Reactome.
DR   GO; GO:0051608; P:histamine transport; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0015695; P:organic cation transport; IDA:MGI.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A3_HUMAN             Reviewed;         556 AA.
AC   O75751; Q5SYN6; Q9UP02;
DE   RecName: Full=Solute carrier family 22 member 3;
DE   AltName: Full=Extraneuronal monoamine transporter;
DE            Short=EMT;
DE   AltName: Full=Organic cation transporter 3;
GN   Name=SLC22A3; Synonyms=EMTH, OCT3;
DR   GO; GO:0005329; F:dopamine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015651; F:quaternary ammonium group transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0019534; F:toxin transporter activity; IEA:Ensembl.
DR   GO; GO:0015872; P:dopamine transport; IEA:Ensembl.
DR   GO; GO:0006855; P:drug transmembrane transport; TAS:Reactome.
DR   GO; GO:0051615; P:histamine uptake; IEA:Ensembl.
DR   GO; GO:0015695; P:organic cation transport; IDA:MGI.
DR   GO; GO:0015697; P:quaternary ammonium group transport; IDA:MGI.
DR   GO; GO:0032098; P:regulation of appetite; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A4_HUMAN             Reviewed;         551 AA.
AC   Q9H015; O14546;
DE   RecName: Full=Solute carrier family 22 member 4;
DE   AltName: Full=Ergothioneine transporter;
DE            Short=ET transporter;
DE   AltName: Full=Organic cation/carnitine transporter 1;
GN   Name=SLC22A4; Synonyms=ETT, OCTN1, UT2H;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015226; F:carnitine transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0015491; F:cation:cation antiporter activity; IDA:BHF-UCL.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0015651; F:quaternary ammonium group transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0008513; F:secondary active organic cation transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0007589; P:body fluid secretion; TAS:ProtInc.
DR   GO; GO:0009437; P:carnitine metabolic process; IEA:Ensembl.
DR   GO; GO:1902603; P:carnitine transmembrane transport; IDA:GOC.
DR   GO; GO:0015879; P:carnitine transport; IDA:MGI.
DR   GO; GO:0015695; P:organic cation transport; TAS:ProtInc.
DR   GO; GO:0015697; P:quaternary ammonium group transport; IDA:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   S22A5_HUMAN             Reviewed;         557 AA.
AC   O76082; A2Q0V1; B2R844; D3DQ87; Q6ZQZ8; Q96EH6;
DE   RecName: Full=Solute carrier family 22 member 5;
DE   AltName: Full=High-affinity sodium-dependent carnitine cotransporter;
DE   AltName: Full=Organic cation/carnitine transporter 2;
GN   Name=SLC22A5; Synonyms=OCTN2;
DR   GO; GO:0042895; F:antibiotic transporter activity; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015226; F:carnitine transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0015238; F:drug transmembrane transporter activity; IC:BHF-UCL.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0015651; F:quaternary ammonium group transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:1902603; P:carnitine transmembrane transport; IDA:GOC.
DR   GO; GO:0015879; P:carnitine transport; IDA:BHF-UCL.
DR   GO; GO:0006855; P:drug transmembrane transport; IC:GOC.
DR   GO; GO:0015893; P:drug transport; IC:BHF-UCL.
DR   GO; GO:0060731; P:positive regulation of intestinal epithelial structure maintenance; IMP:BHF-UCL.
DR   GO; GO:0015697; P:quaternary ammonium group transport; IDA:BHF-UCL.
DR   GO; GO:0052106; P:quorum sensing involved in interaction with host; IMP:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0070715; P:sodium-dependent organic cation transport; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A6_HUMAN             Reviewed;         563 AA.
AC   Q4U2R8; A8MY93; B2D0R6; O95187; O95742; Q7LDA0; Q8N192; Q9NQA6;
AC   Q9NQC2; Q9UBG6; Q9UEQ8;
DE   RecName: Full=Solute carrier family 22 member 6;
DE   AltName: Full=Organic anion transporter 1;
DE            Short=hOAT1;
DE   AltName: Full=PAH transporter;
DE            Short=hPAHT;
DE   AltName: Full=Renal organic anion transporter 1;
DE            Short=hROAT1;
GN   Name=SLC22A6; Synonyms=OAT1, PAHT;
DR   GuidetoPHARMACOLOGY; 1025; -.
DR   GO; GO:0031404; F:chloride ion binding; IEA:Ensembl.
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IDA:UniProtKB.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015742; P:alpha-ketoglutarate transport; IDA:UniProtKB.
DR   GO; GO:0015711; P:organic anion transport; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0097254; P:renal tubular secretion; IMP:UniProtKB.
DR   GO; GO:0031427; P:response to methotrexate; IEA:Ensembl.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A7_HUMAN             Reviewed;         548 AA.
AC   Q9Y694; B2CZX6; Q5T046; Q5T048; Q5T050; Q9H2W5;
DE   RecName: Full=Solute carrier family 22 member 7;
DE   AltName: Full=Novel liver transporter;
DE   AltName: Full=Organic anion transporter 2;
DE            Short=hOAT2;
GN   Name=SLC22A7; Synonyms=NLT, OAT2;
DR   GO; GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015711; P:organic anion transport; TAS:ProtInc.
DR   GO; GO:0035634; P:response to stilbenoid; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A8_HUMAN             Reviewed;         542 AA.
AC   Q8TCC7; B4DPH7; F5GWA8; F5H5J1; O95820; Q59EW9; Q96TC1;
DE   RecName: Full=Solute carrier family 22 member 8;
DE   AltName: Full=Organic anion transporter 3;
DE            Short=hOAT3;
GN   Name=SLC22A8; Synonyms=OAT3;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IDA:UniProtKB.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015651; F:quaternary ammonium group transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0034635; P:glutathione transport; IEA:Ensembl.
DR   GO; GO:0031427; P:response to methotrexate; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22A9_HUMAN             Reviewed;         553 AA.
AC   Q8IVM8; A0AVB7; Q8TCC8; Q8TEC0; Q8WYN7;
DE   RecName: Full=Solute carrier family 22 member 9;
DE   AltName: Full=Organic anion transporter 4;
GN   Name=SLC22A9; Synonyms=OAT4, UST3;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S22AA_HUMAN             Reviewed;         541 AA.
AC   Q63ZE4;
DE   RecName: Full=Solute carrier family 22 member 10;
DE   AltName: Full=Organic anion transporter 5;
GN   Name=SLC22A10; Synonyms=OAT5;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
//
ID   S22AB_HUMAN             Reviewed;         550 AA.
AC   Q9NSA0; A8K426; Q53GR2; Q6ZP72; Q8NBU4;
DE   RecName: Full=Solute carrier family 22 member 11;
DE   AltName: Full=Organic anion transporter 4;
GN   Name=SLC22A11; Synonyms=OAT4;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IDA:UniProtKB.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015711; P:organic anion transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046415; P:urate metabolic process; IMP:BHF-UCL.
//
ID   S22AC_HUMAN             Reviewed;         553 AA.
AC   Q96S37; B7WPG1; G3XAN7; Q19PF7; Q19PF8; Q19PF9; Q19PG0; Q6UXW3;
AC   Q96DT2;
DE   RecName: Full=Solute carrier family 22 member 12;
DE   AltName: Full=Organic anion transporter 4-like protein;
DE   AltName: Full=Renal-specific transporter;
DE            Short=RST;
DE   AltName: Full=Urate anion exchanger 1;
GN   Name=SLC22A12; Synonyms=OATL4, URAT1; ORFNames=UNQ6453/PRO34004;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0015143; F:urate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; NAS:UniProtKB.
DR   GO; GO:0015849; P:organic acid transport; IDA:GOC.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046415; P:urate metabolic process; IMP:BHF-UCL.
DR   GO; GO:0015747; P:urate transport; IDA:UniProtKB.
//
ID   S22AD_HUMAN             Reviewed;         551 AA.
AC   Q9Y226; B2RCV9; Q8IYG1;
DE   RecName: Full=Solute carrier family 22 member 13;
DE   AltName: Full=Organic cation transporter-like 3;
DE            Short=ORCTL-3;
GN   Name=SLC22A13; Synonyms=ORCTL3;
DR   GO; GO:0090416; F:nicotinate transporter activity; IDA:UniProt.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:2001142; P:nicotinate transport; IDA:UniProt.
DR   GO; GO:0015695; P:organic cation transport; NAS:UniProtKB.
DR   GO; GO:0015747; P:urate transport; IDA:UniProt.
//
ID   S22AE_HUMAN             Reviewed;         594 AA.
AC   Q9Y267; A0AVS9; A1L4H6; B2RCX3; Q6DJT3;
DE   RecName: Full=Solute carrier family 22 member 14;
DE   AltName: Full=Organic cation transporter-like 4;
DE            Short=ORCTL-4;
GN   Name=SLC22A14; Synonyms=ORCTL4;
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0015695; P:organic cation transport; NAS:UniProtKB.
//
ID   S22AF_HUMAN             Reviewed;         547 AA.
AC   Q8IZD6; A8MUR3; Q6UXP5; Q8TAL9; Q9NSH5;
DE   RecName: Full=Solute carrier family 22 member 15;
DE   AltName: Full=Fly-like putative transporter 1;
DE            Short=Flipt 1;
GN   Name=SLC22A15; Synonyms=FLIPT1; ORFNames=UNQ9429/PRO34686;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   S22AG_HUMAN             Reviewed;         577 AA.
AC   Q86VW1; O14567; Q5JXM1; Q8IUG8; Q8IZD5; Q96M90; Q96RU0;
DE   RecName: Full=Solute carrier family 22 member 16;
DE   AltName: Full=Carnitine transporter 2;
DE            Short=CT2;
DE   AltName: Full=Fly-like putative transporter 2;
DE            Short=FLIPT2;
DE            Short=Flipt 2;
DE   AltName: Full=Organic cation transporter OKB1;
DE   AltName: Full=Organic cation/carnitine transporter 6;
GN   Name=SLC22A16; Synonyms=OCT6;
DR   GO; GO:0005275; F:amine transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0015226; F:carnitine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0046717; P:acid secretion; IDA:UniProtKB.
DR   GO; GO:0015837; P:amine transport; IDA:GOC.
DR   GO; GO:1902603; P:carnitine transmembrane transport; IDA:GOC.
DR   GO; GO:0015879; P:carnitine transport; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0015695; P:organic cation transport; IDA:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; IMP:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22AH_HUMAN             Reviewed;         538 AA.
AC   Q8WUG5; A4UA13; A8MUT0; Q2TAB0; Q5BKY8; Q86U04; Q9H1D3; Q9NQD5;
DE   RecName: Full=Solute carrier family 22 member 17;
DE   AltName: Full=24p3 receptor;
DE            Short=24p3R;
DE   AltName: Full=Brain-type organic cation transporter;
DE   AltName: Full=Lipocalin-2 receptor;
DE   AltName: Full=Neutrophil gelatinase-associated lipocalin receptor;
DE            Short=NgalR;
GN   Name=SLC22A17; Synonyms=BOCT, BOIT;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; ISS:UniProtKB.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0015891; P:siderophore transport; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:GOC.
//
ID   S22AI_HUMAN             Reviewed;         424 AA.
AC   Q96BI1; O14906; O43562; O60485; O60680; Q7LDS5; Q7LGF7;
DE   RecName: Full=Solute carrier family 22 member 18;
DE   AltName: Full=Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein;
DE   AltName: Full=Efflux transporter-like protein;
DE   AltName: Full=Imprinted multi-membrane-spanning polyspecific transporter-related protein 1;
DE   AltName: Full=Organic cation transporter-like protein 2;
DE            Short=ORCTL-2;
DE   AltName: Full=Solute carrier family 22 member 1-like;
DE   AltName: Full=Tumor-suppressing STF cDNA 5 protein;
DE   AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 5 protein;
DE   AltName: Full=p45-Beckwith-Wiedemann region 1 A;
DE            Short=p45-BWR1A;
GN   Name=SLC22A18;
GN   Synonyms=BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5;
DR   GO; GO:0015238; F:drug transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006855; P:drug transmembrane transport; IDA:GOC.
DR   GO; GO:0015893; P:drug transport; IDA:UniProtKB.
DR   GO; GO:0007588; P:excretion; NAS:UniProtKB.
DR   GO; GO:0015695; P:organic cation transport; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S22AK_HUMAN             Reviewed;         555 AA.
AC   A6NK97; B9EJB2; Q6ZN88;
DE   RecName: Full=Solute carrier family 22 member 20;
DE   AltName: Full=Organic anion transporter 6;
GN   Name=SLC22A20; Synonyms=OAT6;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   S22AN_HUMAN             Reviewed;         686 AA.
AC   A1A5C7; A1A5C8; Q5T8B8; Q6ZMH3; Q8IW73;
DE   RecName: Full=Solute carrier family 22 member 23;
GN   Name=SLC22A23; Synonyms=C6orf85;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   S22AP_HUMAN             Reviewed;         547 AA.
AC   Q6T423; A4FU27;
DE   RecName: Full=Solute carrier family 22 member 25;
DE   AltName: Full=Organic anion transporter UST6;
GN   Name=SLC22A25; Synonyms=UST6;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S22AO_HUMAN             Reviewed;         322 AA.
AC   Q8N4F4;
DE   RecName: Full=Solute carrier family 22 member 24;
GN   Name=SLC22A24;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S22AV_HUMAN             Reviewed;         558 AA.
AC   A6NKX4;
DE   RecName: Full=Putative solute carrier family 22 member 31;
GN   Name=SLC22A31;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   S23A1_HUMAN             Reviewed;         598 AA.
AC   Q9UHI7; O95191; Q8WWB6; Q9UGH4; Q9UI39;
DE   RecName: Full=Solute carrier family 23 member 1;
DE   AltName: Full=Na(+)/L-ascorbic acid transporter 1;
DE   AltName: Full=Sodium-dependent vitamin C transporter 1;
DE            Short=hSVCT1;
DE   AltName: Full=Yolk sac permease-like molecule 3;
GN   Name=SLC23A1; Synonyms=SVCT1, YSPL3;
DR   GuidetoPHARMACOLOGY; 1041; -.
DR   GO; GO:0033300; F:dehydroascorbic acid transporter activity; IMP:UniProtKB.
DR   GO; GO:0008520; F:L-ascorbate:sodium symporter activity; IDA:UniProtKB.
DR   GO; GO:0015229; F:L-ascorbic acid transporter activity; IDA:UniProtKB.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015081; F:sodium ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0070890; F:sodium-dependent L-ascorbate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0070837; P:dehydroascorbic acid transport; IMP:UniProtKB.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; TAS:Reactome.
DR   GO; GO:0015882; P:L-ascorbic acid transport; IDA:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0015851; P:nucleobase transport; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006814; P:sodium ion transport; IDA:UniProtKB.
DR   GO; GO:0070904; P:transepithelial L-ascorbic acid transport; IDA:UniProtKB.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0035461; P:vitamin transmembrane transport; IDA:GOC.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   S23A2_HUMAN             Reviewed;         650 AA.
AC   Q9UGH3; Q8WWR4; Q92512; Q96D54; Q9UNU1; Q9UP85;
DE   RecName: Full=Solute carrier family 23 member 2;
DE   AltName: Full=Na(+)/L-ascorbic acid transporter 2;
DE   AltName: Full=Nucleobase transporter-like 1 protein;
DE   AltName: Full=Sodium-dependent vitamin C transporter 2;
DE            Short=hSVCT2;
DE   AltName: Full=Yolk sac permease-like molecule 2;
GN   Name=SLC23A2; Synonyms=KIAA0238, NBTL1, SLC23A1, SVCT2, YSPL2;
DR   GuidetoPHARMACOLOGY; 1042; -.
DR   GO; GO:0008520; F:L-ascorbate:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0015229; F:L-ascorbic acid transporter activity; IDA:UniProtKB.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0070890; F:sodium-dependent L-ascorbate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0008523; F:sodium-dependent multivitamin transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0019852; P:L-ascorbic acid metabolic process; NAS:UniProtKB.
DR   GO; GO:0015882; P:L-ascorbic acid transport; IDA:UniProtKB.
DR   GO; GO:0015993; P:molecular hydrogen transport; NAS:UniProtKB.
DR   GO; GO:0015851; P:nucleobase transport; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070904; P:transepithelial L-ascorbic acid transport; IDA:UniProtKB.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0035461; P:vitamin transmembrane transport; IDA:GOC.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   S23A3_HUMAN             Reviewed;         610 AA.
AC   Q6PIS1; B7Z512; Q2PYN6; Q96NA6;
DE   RecName: Full=Solute carrier family 23 member 3;
DE   AltName: Full=HPC E2-binding protein 3;
DE   AltName: Full=Na(+)/L-ascorbic acid transporter 3;
DE   AltName: Full=Sodium-dependent vitamin C transporter 3;
GN   Name=SLC23A3; Synonyms=E2BP3, SVCT3;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S23IP_HUMAN             Reviewed;        1000 AA.
AC   Q9Y6Y8; D3DRD2; Q8IXH5; Q9BUK5;
DE   RecName: Full=SEC23-interacting protein;
DE   AltName: Full=p125;
GN   Name=SEC23IP; ORFNames=MSTP053;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
//
ID   S2533_HUMAN             Reviewed;         321 AA.
AC   Q9BSK2;
DE   RecName: Full=Solute carrier family 25 member 33;
DE   AltName: Full=Bone marrow stromal cell mitochondrial carrier protein;
DE            Short=BMSC-MCP;
DE            Short=HuBMSC-MCP;
DE   AltName: Full=Protein PNC1;
GN   Name=SLC25A33;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2534_HUMAN             Reviewed;         304 AA.
AC   Q6PIV7; Q68DV0;
DE   RecName: Full=Solute carrier family 25 member 34;
GN   Name=SLC25A34;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2535_HUMAN             Reviewed;         300 AA.
AC   Q3KQZ1; Q494X5; Q6RGS3; Q8N7Y5;
DE   RecName: Full=Solute carrier family 25 member 35;
GN   Name=SLC25A35;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2536_HUMAN             Reviewed;         311 AA.
AC   Q96CQ1; A8MYF7; Q05CY1; Q9H0G8; Q9NVN5;
DE   RecName: Full=Solute carrier family 25 member 36;
GN   Name=SLC25A36;
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2538_HUMAN             Reviewed;         304 AA.
AC   Q96DW6; Q9NWX2;
DE   RecName: Full=Solute carrier family 25 member 38;
GN   Name=SLC25A38;
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2539_HUMAN             Reviewed;         359 AA.
AC   Q9BZJ4; A8JZZ2; D3DX51; D3DX54; Q4V9M1; Q9P182; Q9UF66; Q9Y379;
DE   RecName: Full=Solute carrier family 25 member 39;
GN   Name=SLC25A39; ORFNames=CGI-69, PRO2163;
DR   GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2540_HUMAN             Reviewed;         338 AA.
AC   Q8TBP6; A8K483; D6W5P6; Q53GB1; Q9UHR1;
DE   RecName: Full=Solute carrier family 25 member 40;
DE   AltName: Full=Mitochondrial carrier family protein;
GN   Name=SLC25A40; Synonyms=MCFP;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2541_HUMAN             Reviewed;         370 AA.
AC   Q8N5S1; A8MQ40; D6W642; Q8N7R4;
DE   RecName: Full=Solute carrier family 25 member 41;
GN   Name=SLC25A41;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2542_HUMAN             Reviewed;         318 AA.
AC   Q86VD7; D2T2J5; O14553; O43378;
DE   RecName: Full=Mitochondrial coenzyme A transporter SLC25A42;
DE   AltName: Full=Solute carrier family 25 member 42;
GN   Name=SLC25A42;
DR   GO; GO:0043262; F:adenosine-diphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0015217; F:ADP transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0080122; F:AMP transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005347; F:ATP transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015228; F:coenzyme A transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015866; P:ADP transport; IDA:UniProtKB.
DR   GO; GO:0080121; P:AMP transport; IDA:UniProtKB.
DR   GO; GO:0015867; P:ATP transport; IDA:UniProtKB.
DR   GO; GO:0035349; P:coenzyme A transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
//
ID   S2543_HUMAN             Reviewed;         341 AA.
AC   Q8WUT9; O75854; Q8N9L5;
DE   RecName: Full=Solute carrier family 25 member 43;
GN   Name=SLC25A43;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2544_HUMAN             Reviewed;         314 AA.
AC   Q96H78; O75034;
DE   RecName: Full=Solute carrier family 25 member 44;
GN   Name=SLC25A44; Synonyms=KIAA0446;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2545_HUMAN             Reviewed;         288 AA.
AC   Q8N413; Q6PL49; Q8IW29;
DE   RecName: Full=Solute carrier family 25 member 45;
GN   Name=SLC25A45;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2547_HUMAN             Reviewed;         308 AA.
AC   Q6Q0C1; B2RP39; Q68CL2; Q6PZD8; Q86U14;
DE   RecName: Full=Solute carrier family 25 member 47;
DE   AltName: Full=Hepatocellular carcinoma down-regulated mitochondrial carrier protein;
GN   Name=SLC25A47; Synonyms=C14orf68, HDMCP; ORFNames=HMFN1655;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2546_HUMAN             Reviewed;         418 AA.
AC   Q96AG3; A8K2F2; D3DSZ6; Q04197;
DE   RecName: Full=Solute carrier family 25 member 46;
GN   Name=SLC25A46; Synonyms=TB1;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2548_HUMAN             Reviewed;         311 AA.
AC   Q6ZT89; Q8TAV9;
DE   RecName: Full=Solute carrier family 25 member 48;
GN   Name=SLC25A48;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S2551_HUMAN             Reviewed;         297 AA.
AC   Q9H1U9;
DE   RecName: Full=Solute carrier family 25 member 51;
DE   AltName: Full=Mitochondrial carrier triple repeat protein 1;
GN   Name=SLC25A51; Synonyms=MCART1;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2553_HUMAN             Reviewed;         307 AA.
AC   Q5H9E4; B2RTT9;
DE   RecName: Full=Solute carrier family 25 member 53;
DE   AltName: Full=Mitochondrial carrier triple repeat protein 6;
GN   Name=SLC25A53; Synonyms=MCART6;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2552_HUMAN             Reviewed;         297 AA.
AC   Q3SY17;
DE   RecName: Full=Solute carrier family 25 member 52;
DE   AltName: Full=Mitochondrial carrier triple repeat protein 2;
GN   Name=SLC25A52; Synonyms=MCART2;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S2610_HUMAN             Reviewed;         563 AA.
AC   Q8NG04; A6NMJ2; B6ZDQ3; Q6ZWI7;
DE   RecName: Full=Solute carrier family 26 member 10;
GN   Name=SLC26A10;
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; IEA:InterPro.
//
ID   S2611_HUMAN             Reviewed;         606 AA.
AC   Q86WA9; B2RCI7; Q86VX1; Q86YX7; Q8IV11; Q8N2I1; Q8NG03;
DE   RecName: Full=Sodium-independent sulfate anion transporter;
DE   AltName: Full=Solute carrier family 26 member 11;
GN   Name=SLC26A11;
DR   GO; GO:0008509; F:anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015301; F:anion:anion antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008272; P:sulfate transport; IDA:UniProtKB.
//
ID   S26A1_HUMAN             Reviewed;         701 AA.
AC   Q9H2B4; A8K9N2; Q7Z5R3; Q96BK0;
DE   RecName: Full=Sulfate anion transporter 1;
DE            Short=SAT-1;
DE   AltName: Full=Solute carrier family 26 member 1;
GN   Name=SLC26A1; Synonyms=SAT1;
DR   GO; GO:0015301; F:anion:anion antiporter activity; ISS:UniProtKB.
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0019531; F:oxalate transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0050428; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:1902476; P:chloride transmembrane transport; ISS:GOC.
DR   GO; GO:0006821; P:chloride transport; ISS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0019532; P:oxalate transport; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:1902358; P:sulfate transmembrane transport; ISS:GOC.
DR   GO; GO:0008272; P:sulfate transport; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   S26A2_HUMAN             Reviewed;         739 AA.
AC   P50443; A8K2U3; B2R6J1; Q6N051;
DE   RecName: Full=Sulfate transporter;
DE   AltName: Full=Diastrophic dysplasia protein;
DE   AltName: Full=Solute carrier family 26 member 2;
GN   Name=SLC26A2; Synonyms=DTD, DTDST;
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0050428; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:1902358; P:sulfate transmembrane transport; TAS:GOC.
DR   GO; GO:0008272; P:sulfate transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   S26A3_HUMAN             Reviewed;         764 AA.
AC   P40879;
DE   RecName: Full=Chloride anion exchanger;
DE   AltName: Full=Down-regulated in adenoma;
DE            Short=Protein DRA;
DE   AltName: Full=Solute carrier family 26 member 3;
GN   Name=SLC26A3; Synonyms=DRA;
DR   GO; GO:0015301; F:anion:anion antiporter activity; IEA:Ensembl.
DR   GO; GO:0015106; F:bicarbonate transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006820; P:anion transport; TAS:ProtInc.
DR   GO; GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; ISS:GOC.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0051454; P:intracellular pH elevation; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0060081; P:membrane hyperpolarization; ISS:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0048240; P:sperm capacitation; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S26A4_HUMAN             Reviewed;         780 AA.
AC   O43511; O43170;
DE   RecName: Full=Pendrin;
DE   AltName: Full=Sodium-independent chloride/iodide transporter;
DE   AltName: Full=Solute carrier family 26 member 4;
GN   Name=SLC26A4; Synonyms=PDS;
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015111; F:iodide transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:1902476; P:chloride transmembrane transport; TAS:GOC.
DR   GO; GO:0015698; P:inorganic anion transport; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006885; P:regulation of pH; ISS:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:1902358; P:sulfate transmembrane transport; TAS:GOC.
DR   GO; GO:0008272; P:sulfate transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S26A5_HUMAN             Reviewed;         744 AA.
AC   P58743; Q496J2; Q7Z7F3; Q86UF8; Q86UF9; Q86UG0;
DE   RecName: Full=Prestin;
DE   AltName: Full=Solute carrier family 26 member 5;
GN   Name=SLC26A5; Synonyms=PRES;
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
//
ID   S26A6_HUMAN             Reviewed;         759 AA.
AC   Q9BXS9; Q548A7; Q96Q90; Q9NQU1;
DE   RecName: Full=Solute carrier family 26 member 6;
DE   AltName: Full=Anion exchange transporter;
DE   AltName: Full=Pendrin-like protein 1;
DE            Short=Pendrin-L1;
GN   Name=SLC26A6;
DR   GO; GO:0015301; F:anion:anion antiporter activity; IDA:UniProtKB.
DR   GO; GO:0015106; F:bicarbonate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0015108; F:chloride transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015660; F:formate efflux transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015499; F:formate transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015659; F:formate uptake transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0019531; F:oxalate transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0038166; P:angiotensin-activated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006820; P:anion transport; IDA:GOC.
DR   GO; GO:0015701; P:bicarbonate transport; IDA:GOC.
DR   GO; GO:0071320; P:cellular response to cAMP; ISS:UniProtKB.
DR   GO; GO:0071332; P:cellular response to fructose stimulus; ISS:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:GOC.
DR   GO; GO:0042045; P:epithelial fluid transport; ISS:UniProtKB.
DR   GO; GO:0015724; P:formate transport; ISS:UniProtKB.
DR   GO; GO:0050892; P:intestinal absorption; ISS:UniProtKB.
DR   GO; GO:0051454; P:intracellular pH elevation; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015797; P:mannitol transport; ISS:UniProtKB.
DR   GO; GO:0019532; P:oxalate transport; IMP:UniProtKB.
DR   GO; GO:0046724; P:oxalic acid secretion; ISS:UniProtKB.
DR   GO; GO:2001150; P:positive regulation of dipeptide transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0070528; P:protein kinase C signaling; IDA:UniProtKB.
DR   GO; GO:0051453; P:regulation of intracellular pH; IDA:UniProtKB.
DR   GO; GO:0048240; P:sperm capacitation; ISS:UniProtKB.
DR   GO; GO:1902358; P:sulfate transmembrane transport; IDA:GOC.
DR   GO; GO:0008272; P:sulfate transport; IMP:UniProtKB.
DR   GO; GO:0030321; P:transepithelial chloride transport; IMP:UniProtKB.
DR   GO; GO:0070633; P:transepithelial transport; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S26A7_HUMAN             Reviewed;         656 AA.
AC   Q8TE54; Q24JS8; Q8TE53; Q96RN2;
DE   RecName: Full=Anion exchange transporter;
DE   AltName: Full=Solute carrier family 26 member 7;
GN   Name=SLC26A7; Synonyms=SUT2;
DR   GO; GO:0015301; F:anion:anion antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015106; F:bicarbonate transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005254; F:chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0019531; F:oxalate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0006820; P:anion transport; IDA:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; ISS:UniProtKB.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:UniProtKB.
DR   GO; GO:0001696; P:gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0019532; P:oxalate transport; IDA:UniProtKB.
DR   GO; GO:1902358; P:sulfate transmembrane transport; IDA:GOC.
DR   GO; GO:0008272; P:sulfate transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S26A8_HUMAN             Reviewed;         970 AA.
AC   Q96RN1; Q5JVR5; Q812C7; Q8TC65; Q96MA0; Q96PK8;
DE   RecName: Full=Testis anion transporter 1;
DE   AltName: Full=Anion exchange transporter;
DE   AltName: Full=Solute carrier family 26 member 8;
GN   Name=SLC26A8; Synonyms=TAT1;
DR   GO; GO:0015301; F:anion:anion antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0005254; F:chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0019531; F:oxalate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015116; F:sulfate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0006820; P:anion transport; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0019532; P:oxalate transport; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:1902358; P:sulfate transmembrane transport; IDA:GOC.
DR   GO; GO:0008272; P:sulfate transport; IDA:UniProtKB.
//
ID   S26A9_HUMAN             Reviewed;         791 AA.
AC   Q7LBE3; A7E2V6; B1AVM8; B1AVM9; B7ZKK2; Q96PK9; Q96RN0;
DE   RecName: Full=Solute carrier family 26 member 9;
DE   AltName: Full=Anion transporter/exchanger protein 9;
GN   Name=SLC26A9;
DR   GO; GO:0015301; F:anion:anion antiporter activity; IDA:UniProt.
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProt.
DR   GO; GO:0005254; F:chloride channel activity; IDA:UniProt.
DR   GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006820; P:anion transport; IDA:UniProt.
DR   GO; GO:0015701; P:bicarbonate transport; IDA:UniProt.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:UniProt.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S27A1_HUMAN             Reviewed;         646 AA.
AC   Q6PCB7; A6NIH2;
DE   RecName: Full=Long-chain fatty acid transport protein 1;
DE            Short=FATP-1;
DE            Short=Fatty acid transport protein 1;
DE            EC=6.2.1.-;
DE   AltName: Full=Solute carrier family 27 member 1;
GN   Name=SLC27A1; Synonyms=ACSVL5, FATP1;
DR   GO; GO:0015245; F:fatty acid transporter activity; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IEA:Ensembl.
DR   GO; GO:0033211; P:adiponectin-activated signaling pathway; IEA:Ensembl.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.
DR   GO; GO:0001579; P:medium-chain fatty acid transport; IEA:Ensembl.
DR   GO; GO:0071072; P:negative regulation of phospholipid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006655; P:phosphatidylglycerol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006659; P:phosphatidylserine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0031652; P:positive regulation of heat generation; IEA:Ensembl.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S27A2_HUMAN             Reviewed;         620 AA.
AC   O14975; A8K2J7; Q53FY6; Q6PF09;
DE   RecName: Full=Very long-chain acyl-CoA synthetase;
DE            Short=VLACS;
DE            Short=VLCS;
DE            EC=6.2.1.-;
DE   AltName: Full=Fatty acid transport protein 2;
DE            Short=FATP-2;
DE   AltName: Full=Fatty-acid-coenzyme A ligase, very long-chain 1;
DE   AltName: Full=Long-chain-fatty-acid--CoA ligase;
DE            EC=6.2.1.3;
DE   AltName: Full=Solute carrier family 27 member 2;
DE   AltName: Full=THCA-CoA ligase;
DE   AltName: Full=Very long-chain-fatty-acid-CoA ligase;
GN   Name=SLC27A2; Synonyms=ACSVL1, FACVL1, FATP2, VLACS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0015245; F:fatty acid transporter activity; IEA:Ensembl.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0050197; F:phytanate-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0070251; F:pristanate-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0001561; P:fatty acid alpha-oxidation; IDA:UniProtKB.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.
DR   GO; GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0097089; P:methyl-branched fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042760; P:very long-chain fatty acid catabolic process; IEA:Ensembl.
//
ID   S27A4_HUMAN             Reviewed;         643 AA.
AC   Q6P1M0; A8K2F7; O95186;
DE   RecName: Full=Long-chain fatty acid transport protein 4;
DE            Short=FATP-4;
DE            Short=Fatty acid transport protein 4;
DE            EC=6.2.1.-;
DE   AltName: Full=Solute carrier family 27 member 4;
GN   Name=SLC27A4; Synonyms=ACSVL4, FATP4;
DR   GO; GO:0015245; F:fatty acid transporter activity; TAS:ProtInc.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IEA:Ensembl.
DR   GO; GO:0015908; P:fatty acid transport; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.
DR   GO; GO:0001579; P:medium-chain fatty acid transport; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0042760; P:very long-chain fatty acid catabolic process; IEA:Ensembl.
//
ID   S27A3_HUMAN             Reviewed;         730 AA.
AC   Q5K4L6; Q5VUQ7; Q5VUQ8; Q5VUR3; Q6ZV16; Q8N2X7; Q8TEJ0; Q96SW5;
AC   Q9BTJ5; Q9BTY5;
DE   RecName: Full=Long-chain fatty acid transport protein 3;
DE            Short=FATP-3;
DE            Short=Fatty acid transport protein 3;
DE            EC=6.2.1.-;
DE   AltName: Full=Solute carrier family 27 member 3;
DE   AltName: Full=Very long-chain acyl-CoA synthetase homolog 3;
DE            Short=VLCS-3;
GN   Name=SLC27A3; Synonyms=ACSVL3, FATP3;
GN   ORFNames=PSEC0067, UNQ367/PRO703;
DR   GO; GO:0004321; F:fatty-acyl-CoA synthase activity; IEA:Ensembl.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
//
ID   S27A5_HUMAN             Reviewed;         690 AA.
AC   Q9Y2P5; B3KVP6;
DE   RecName: Full=Bile acyl-CoA synthetase;
DE            Short=BACS;
DE            EC=6.2.1.7;
DE   AltName: Full=Bile acid-CoA ligase;
DE            Short=BA-CoA ligase;
DE            Short=BAL;
DE   AltName: Full=Cholate--CoA ligase;
DE   AltName: Full=Fatty acid transport protein 5;
DE            Short=FATP-5;
DE   AltName: Full=Fatty-acid-coenzyme A ligase, very long-chain 3;
DE   AltName: Full=Solute carrier family 27 member 5;
DE   AltName: Full=Very long-chain acyl-CoA synthetase homolog 2;
DE            Short=VLCS-H2;
DE            Short=VLCSH2;
DE   AltName: Full=Very long-chain acyl-CoA synthetase-related protein;
DE            Short=VLACS-related;
DE            Short=VLACSR;
GN   Name=SLC27A5; Synonyms=ACSB, ACSVL6, FACVL3, FATP5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0047747; F:cholate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015245; F:fatty acid transporter activity; IEA:Ensembl.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:UniProtKB.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0046951; P:ketone body biosynthetic process; IEA:Ensembl.
DR   GO; GO:0015911; P:plasma membrane long-chain fatty acid transport; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006642; P:triglyceride mobilization; IEA:Ensembl.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IDA:UniProtKB.
//
ID   S27A6_HUMAN             Reviewed;         619 AA.
AC   Q9Y2P4; Q6IAM5; Q7Z6E6; Q86YF6;
DE   RecName: Full=Long-chain fatty acid transport protein 6;
DE            Short=FATP-6;
DE            Short=Fatty acid transport protein 6;
DE   AltName: Full=Fatty-acid-coenzyme A ligase, very long-chain 2;
DE   AltName: Full=Solute carrier family 27 member 6;
DE   AltName: Full=Very long-chain acyl-CoA synthetase homolog 1;
DE            Short=VLCSH1;
DE            Short=hVLCS-H1;
GN   Name=SLC27A6; Synonyms=ACSVL2, FACVL2, FATP1;
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IEA:Ensembl.
DR   GO; GO:0001676; P:long-chain fatty acid metabolic process; TAS:GOC.
DR   GO; GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; TAS:ProtInc.
//
ID   S28A1_HUMAN             Reviewed;         649 AA.
AC   O00337; A0AV42; A8K7I2; O00335; O00336; Q5U5S6; Q5U648; Q9UEZ9;
DE   RecName: Full=Sodium/nucleoside cotransporter 1;
DE   AltName: Full=Concentrative nucleoside transporter 1;
DE            Short=CNT 1;
DE            Short=hCNT1;
DE   AltName: Full=Na(+)/nucleoside cotransporter 1;
DE   AltName: Full=Sodium-coupled nucleoside transporter 1;
DE   AltName: Full=Solute carrier family 28 member 1;
GN   Name=SLC28A1; Synonyms=CNT1;
DR   GO; GO:0001882; F:nucleoside binding; IEA:InterPro.
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005415; F:nucleoside:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:1901642; P:nucleoside transmembrane transport; TAS:GOC.
DR   GO; GO:0015858; P:nucleoside transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S28A2_HUMAN             Reviewed;         658 AA.
AC   O43868; A8K7F9; O43239; Q52LZ0;
DE   RecName: Full=Sodium/nucleoside cotransporter 2;
DE   AltName: Full=Concentrative nucleoside transporter 2;
DE            Short=CNT 2;
DE            Short=hCNT2;
DE   AltName: Full=Na(+)/nucleoside cotransporter 2;
DE   AltName: Full=Sodium-coupled nucleoside transporter 2;
DE   AltName: Full=Sodium/purine nucleoside co-transporter;
DE            Short=SPNT;
DE   AltName: Full=Solute carrier family 28 member 2;
GN   Name=SLC28A2; Synonyms=CNT2;
DR   GO; GO:0001882; F:nucleoside binding; IEA:InterPro.
DR   GO; GO:0005415; F:nucleoside:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0015211; F:purine nucleoside transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0015860; P:purine nucleoside transmembrane transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S28A3_HUMAN             Reviewed;         691 AA.
AC   Q9HAS3; A8K9Y4; B1AML0; B2RA51; B4E2S8; F5GYE3;
DE   RecName: Full=Solute carrier family 28 member 3;
DE   AltName: Full=Concentrative Na(+)-nucleoside cotransporter 3;
DE            Short=CNT 3;
DE            Short=hCNT3;
GN   Name=SLC28A3; Synonyms=CNT3;
DR   GO; GO:0001882; F:nucleoside binding; IEA:InterPro.
DR   GO; GO:0015390; F:purine-specific nucleoside:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0015389; F:pyrimidine- and adenine-specific:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0015864; P:pyrimidine nucleoside transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S29A2_HUMAN             Reviewed;         456 AA.
AC   Q14542; B3KPY7; O43530; Q52M84; Q96R00; Q9UPE0;
DE   RecName: Full=Equilibrative nucleoside transporter 2;
DE   AltName: Full=36 kDa nucleolar protein HNP36;
DE   AltName: Full=Delayed-early response protein 12;
DE   AltName: Full=Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter;
DE            Short=Equilibrative NBMPR-insensitive nucleoside transporter;
DE   AltName: Full=Hydrophobic nucleolar protein, 36 kDa;
DE   AltName: Full=Nucleoside transporter, ei-type;
DE   AltName: Full=Solute carrier family 29 member 2;
GN   Name=SLC29A2; Synonyms=DER12, ENT2, HNP36;
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:1901642; P:nucleoside transmembrane transport; TAS:GOC.
DR   GO; GO:0015858; P:nucleoside transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S29A1_HUMAN             Reviewed;         456 AA.
AC   Q99808; B3KQY5; Q5T9W9; Q9UJY2;
DE   RecName: Full=Equilibrative nucleoside transporter 1;
DE   AltName: Full=Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter;
DE            Short=Equilibrative NBMPR-sensitive nucleoside transporter;
DE   AltName: Full=Nucleoside transporter, es-type;
DE   AltName: Full=Solute carrier family 29 member 1;
GN   Name=SLC29A1; Synonyms=ENT1;
DR   GuidetoPHARMACOLOGY; 1117; -.
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:1901642; P:nucleoside transmembrane transport; TAS:GOC.
DR   GO; GO:0015858; P:nucleoside transport; IDA:UniProtKB.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0030431; P:sleep; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015862; P:uridine transport; IEA:Ensembl.
//
ID   S29A3_HUMAN             Reviewed;         475 AA.
AC   Q9BZD2; B2RB50; B4E2Z9; B7ZA37; Q0VAM9; Q5T465; Q7RTT8; Q8IVZ0;
AC   Q9BWI2; Q9NUS9;
DE   RecName: Full=Equilibrative nucleoside transporter 3;
DE            Short=hENT3;
DE   AltName: Full=Solute carrier family 29 member 3;
GN   Name=SLC29A3; Synonyms=ENT3; ORFNames=UNQ717/PRO1380;
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S29A4_HUMAN             Reviewed;         530 AA.
AC   Q7RTT9; Q6PJ08; Q86WY8; Q8NAR3; Q8NBM2;
DE   RecName: Full=Equilibrative nucleoside transporter 4;
DE            Short=hENT4;
DE   AltName: Full=Plasma membrane monoamine transporter;
DE   AltName: Full=Solute carrier family 29 member 4;
GN   Name=SLC29A4; Synonyms=ENT4, PMAT; ORFNames=PSEC0113;
DR   GuidetoPHARMACOLOGY; 1120; -.
DR   GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S2A4R_HUMAN             Reviewed;         387 AA.
AC   Q9NR83; Q6F6I6; Q6F6I7; Q6GTK5; Q8TAH5; Q8WVW7; Q96QD3; Q9BV85;
DE   RecName: Full=SLC2A4 regulator;
DE   AltName: Full=GLUT4 enhancer factor;
DE            Short=GEF;
DE   AltName: Full=Huntington disease gene regulatory region-binding protein 1;
DE            Short=HDBP-1;
GN   Name=SLC2A4RG; Synonyms=HDBP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   S29P2_HUMAN             Reviewed;         249 AA.
AC   Q8IUI4;
DE   RecName: Full=Putative protein SNX29P2;
DE   AltName: Full=RUN domain-containing protein 2C;
DE   AltName: Full=Sorting nexin 29 protein pseudogene 2;
GN   Name=SNX29P2; Synonyms=RUNDC2C;
//
ID   S30BP_HUMAN             Reviewed;         308 AA.
AC   Q9UHR5; B3KML7; Q8N1R5; Q8TDR8; Q96D27;
DE   RecName: Full=SAP30-binding protein;
DE   AltName: Full=Transcriptional regulator protein HCNGP;
GN   Name=SAP30BP; Synonyms=HCNGP, HTRG, HTRP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   S31A2_HUMAN             Reviewed;        1347 AA.
AC   Q5RGS2;
DE   RecName: Full=Spermatogenesis-associated protein 31A2;
DE   AltName: Full=Protein FAM75A2;
GN   Name=SPATA31A2; Synonyms=FAM75A2;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31A6_HUMAN             Reviewed;        1343 AA.
AC   Q5VVP1;
DE   RecName: Full=Spermatogenesis-associated protein 31A6;
DE   AltName: Full=Protein FAM75A6;
GN   Name=SPATA31A6; Synonyms=FAM75A6;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31A4_HUMAN             Reviewed;        1347 AA.
AC   Q4VX67;
DE   RecName: Full=Spermatogenesis-associated protein 31A4;
DE   AltName: Full=Protein FAM75A4;
GN   Name=SPATA31A4; Synonyms=FAM75A4;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31A5_HUMAN             Reviewed;        1347 AA.
AC   Q5VU36;
DE   RecName: Full=Spermatogenesis-associated protein 31A5;
DE   AltName: Full=Protein FAM75A5;
GN   Name=SPATA31A5; Synonyms=FAM75A5;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31A1_HUMAN             Reviewed;        1347 AA.
AC   Q5TZJ5;
DE   RecName: Full=Spermatogenesis-associated protein 31A1;
DE   AltName: Full=Protein FAM75A1;
GN   Name=SPATA31A1; Synonyms=C9orf36, FAM75A1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31A7_HUMAN             Reviewed;        1347 AA.
AC   Q8IWB4; Q5TZK4; Q9Y4Q5;
DE   RecName: Full=Spermatogenesis-associated protein 31A7;
DE   AltName: Full=Protein FAM75A7;
GN   Name=SPATA31A7; Synonyms=FAM75A7;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31B1_HUMAN             Reviewed;         182 AA.
AC   Q5VZV4;
DE   RecName: Full=Putative spermatogenesis-associated protein 31B1;
DE   AltName: Full=Protein FAM75B;
GN   Name=SPATA31B1; Synonyms=C9orf36B, FAM75B;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31C1_HUMAN             Reviewed;        1188 AA.
AC   P0DKV0;
DE   RecName: Full=Spermatogenesis-associated protein 31C1;
DE   AltName: Full=Protein FAM75C1;
GN   Name=SPATA31C1; Synonyms=FAM75C1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31C2_HUMAN             Reviewed;        1134 AA.
AC   B4DYI2;
DE   RecName: Full=Spermatogenesis-associated protein 31C2;
DE   AltName: Full=Protein FAM75C2;
GN   Name=SPATA31C2; Synonyms=FAM75C2;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31A3_HUMAN             Reviewed;        1347 AA.
AC   Q5VYP0;
DE   RecName: Full=Spermatogenesis-associated protein 31A3;
DE   AltName: Full=Protein FAM75A3;
GN   Name=SPATA31A3; Synonyms=FAM75A3;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31D1_HUMAN             Reviewed;        1576 AA.
AC   Q6ZQQ2;
DE   RecName: Full=Spermatogenesis-associated protein 31D1;
DE   AltName: Full=Protein FAM75D1;
GN   Name=SPATA31D1; Synonyms=FAM75D1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31D4_HUMAN             Reviewed;         917 AA.
AC   Q6ZUB0;
DE   RecName: Full=Putative spermatogenesis-associated protein 31D4;
DE   AltName: Full=Protein FAM75D4;
GN   Name=SPATA31D4; Synonyms=FAM75D4;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S31E1_HUMAN             Reviewed;        1445 AA.
AC   Q6ZUB1; B2RPB1; Q5SQC9; Q8NA41; Q8ND27;
DE   RecName: Full=Spermatogenesis-associated protein 31E1;
DE   AltName: Full=Protein FAM75E1;
GN   Name=SPATA31E1; Synonyms=C9orf79, FAM75E1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S352B_HUMAN             Reviewed;         405 AA.
AC   P0CK96; B3KWR0; O75035; Q2TAY8; Q569F8; Q5CZA4; Q9Y3J8;
DE   RecName: Full=Solute carrier family 35 member E2B;
GN   Name=SLC35E2B; Synonyms=KIAA0447;
//
ID   S31D3_HUMAN             Reviewed;         917 AA.
AC   P0C874;
DE   RecName: Full=Putative spermatogenesis-associated protein 31D3;
DE   AltName: Full=Protein FAM75D3;
GN   Name=SPATA31D3; Synonyms=FAM75D3;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   S35A1_HUMAN             Reviewed;         337 AA.
AC   P78382; Q5W1L8;
DE   RecName: Full=CMP-sialic acid transporter;
DE            Short=CMP-SA-Tr;
DE            Short=CMP-Sia-Tr;
DE   AltName: Full=Solute carrier family 35 member A1;
GN   Name=SLC35A1;
DR   GO; GO:0005456; F:CMP-N-acetylneuraminate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005351; F:sugar:proton symporter activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0015782; P:CMP-N-acetylneuraminate transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S35A2_HUMAN             Reviewed;         396 AA.
AC   P78381; A8K2L9; A8K9V1; B4DPT2; E7EW45; Q8IV21; Q92553;
DE   RecName: Full=UDP-galactose translocator;
DE   AltName: Full=Solute carrier family 35 member A2;
DE   AltName: Full=UDP-galactose transporter;
DE            Short=UDP-Gal-Tr;
DE            Short=UGT;
GN   Name=SLC35A2; Synonyms=UGALT, UGT, UGTL;
DR   GO; GO:0005338; F:nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005351; F:sugar:proton symporter activity; IEA:InterPro.
DR   GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006012; P:galactose metabolic process; TAS:ProtInc.
DR   GO; GO:0015780; P:nucleotide-sugar transport; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015785; P:UDP-galactose transport; TAS:ProtInc.
//
ID   S35A3_HUMAN             Reviewed;         325 AA.
AC   Q9Y2D2; A8K3F8; D3DT54; Q68CR2; Q9BSB7;
DE   RecName: Full=UDP-N-acetylglucosamine transporter;
DE   AltName: Full=Golgi UDP-GlcNAc transporter;
DE   AltName: Full=Solute carrier family 35 member A3;
GN   Name=SLC35A3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005351; F:sugar:proton symporter activity; IEA:InterPro.
DR   GO; GO:0005462; F:UDP-N-acetylglucosamine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006047; P:UDP-N-acetylglucosamine metabolic process; TAS:ProtInc.
DR   GO; GO:0015788; P:UDP-N-acetylglucosamine transport; IMP:UniProtKB.
//
ID   S35A4_HUMAN             Reviewed;         324 AA.
AC   Q96G79; A8K013;
DE   RecName: Full=Probable UDP-sugar transporter protein SLC35A4;
DE   AltName: Full=Solute carrier family 35 member A4;
GN   Name=SLC35A4;
DR   GO; GO:0005351; F:sugar:proton symporter activity; IEA:InterPro.
//
ID   S35A5_HUMAN             Reviewed;         424 AA.
AC   Q9BS91; D3DN66; Q69YY6; Q6ZMD6; Q9NWM9;
DE   RecName: Full=Probable UDP-sugar transporter protein SLC35A5;
DE   AltName: Full=Solute carrier family 35 member A5;
GN   Name=SLC35A5; ORFNames=UNQ164/PRO190;
DR   GO; GO:0005338; F:nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005351; F:sugar:proton symporter activity; IEA:InterPro.
DR   GO; GO:0015780; P:nucleotide-sugar transport; IEA:InterPro.
//
ID   S35B1_HUMAN             Reviewed;         322 AA.
AC   P78383; B4DEC4; J3KQV4; Q96EW7;
DE   RecName: Full=Solute carrier family 35 member B1;
DE   AltName: Full=UDP-galactose transporter-related protein 1;
DE            Short=UGTrel1;
DE            Short=hUGTrel1;
GN   Name=SLC35B1; Synonyms=UGTREL1;
DR   GO; GO:0005459; F:UDP-galactose transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0072334; P:UDP-galactose transmembrane transport; TAS:GOC.
//
ID   S35B2_HUMAN             Reviewed;         432 AA.
AC   Q8TB61; B4DDU9; F5H7Y9; Q2VY06; Q53GA3; Q5T9W1; Q5T9W2; Q7Z2G3;
AC   Q8NBK6; Q96AR6;
DE   RecName: Full=Adenosine 3'-phospho 5'-phosphosulfate transporter 1;
DE   AltName: Full=PAPS transporter 1;
DE   AltName: Full=Putative MAPK-activating protein PM15;
DE   AltName: Full=Putative NF-kappa-B-activating protein 48;
DE   AltName: Full=Solute carrier family 35 member B2;
GN   Name=SLC35B2; Synonyms=PAPST1; ORFNames=PSEC0149;
DR   GO; GO:0046964; F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:1902559; P:3'-phospho-5'-adenylyl sulfate transmembrane transport; IDA:GOC.
DR   GO; GO:0050428; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0046963; P:3'-phosphoadenosine 5'-phosphosulfate transport; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   S35B3_HUMAN             Reviewed;         401 AA.
AC   Q9H1N7; A6NKX9; Q1XH11; Q6MZJ0; Q7Z662; Q9Y308;
DE   RecName: Full=Adenosine 3'-phospho 5'-phosphosulfate transporter 2;
DE   AltName: Full=3'-phosphoadenosine 5'-phosphosulfate transporter;
DE   AltName: Full=PAPS transporter 2;
DE   AltName: Full=Solute carrier family 35 member B3;
GN   Name=SLC35B3; Synonyms=C6orf196, PAPST2; ORFNames=CGI-19;
DR   GO; GO:0050428; P:3'-phosphoadenosine 5'-phosphosulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   S35B4_HUMAN             Reviewed;         331 AA.
AC   Q969S0; A4D1P3; A6NNS4; Q53GQ7; Q8TCU7; Q96K33;
DE   RecName: Full=UDP-xylose and UDP-N-acetylglucosamine transporter;
DE   AltName: Full=Solute carrier family 35 member B4;
DE   AltName: Full=YEA4 homolog;
GN   Name=SLC35B4; Synonyms=YEA4; ORFNames=PSEC0055;
DR   GO; GO:0005462; F:UDP-N-acetylglucosamine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005464; F:UDP-xylose transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015788; P:UDP-N-acetylglucosamine transport; IDA:UniProtKB.
DR   GO; GO:0015790; P:UDP-xylose transport; IDA:UniProtKB.
//
ID   S35C2_HUMAN             Reviewed;         365 AA.
AC   Q9NQQ7; E1P5T0; Q5JW05; Q96CJ8; Q9Y304;
DE   RecName: Full=Solute carrier family 35 member C2;
DE   AltName: Full=Ovarian cancer-overexpressed gene 1 protein;
GN   Name=SLC35C2; Synonyms=C20orf5, OVCOV1; ORFNames=CGI-15;
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0036066; P:protein O-linked fucosylation; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35D1_HUMAN             Reviewed;         355 AA.
AC   Q9NTN3; A8K185; Q52LU5; Q92548;
DE   RecName: Full=UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter;
DE            Short=UDP-GlcA/UDP-GalNAc transporter;
DE   AltName: Full=Solute carrier family 35 member D1;
DE   AltName: Full=UDP-galactose transporter-related protein 7;
DE            Short=UGTrel7;
GN   Name=SLC35D1; Synonyms=KIAA0260, UGTREL7;
DR   GO; GO:0005461; F:UDP-glucuronic acid transmembrane transporter activity; TAS:Reactome.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0052695; P:cellular glucuronidation; TAS:Reactome.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006065; P:UDP-glucuronate biosynthetic process; TAS:Reactome.
DR   GO; GO:0015787; P:UDP-glucuronic acid transport; TAS:GOC.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   S35D2_HUMAN             Reviewed;         337 AA.
AC   Q76EJ3; O95454; Q498C1; Q75W21; Q7Z5X5;
DE   RecName: Full=UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter;
DE   AltName: Full=Homolog of Fringe connection protein 1;
DE            Short=HFRC1;
DE   AltName: Full=SQV7-like protein;
DE            Short=SQV7L;
DE   AltName: Full=Solute carrier family 35 member D2;
DE   AltName: Full=UDP-galactose transporter-related protein 8;
DE            Short=UGTrel8;
GN   Name=SLC35D2; Synonyms=HFRC, UGTREL8;
DR   GO; GO:0005338; F:nucleotide-sugar transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:1901264; P:carbohydrate derivative transport; NAS:GOC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:1901679; P:nucleotide transmembrane transport; NAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S35D3_HUMAN             Reviewed;         416 AA.
AC   Q5M8T2; B4DI58; Q5QNZ6; Q6NX71;
DE   RecName: Full=Solute carrier family 35 member D3;
DE   AltName: Full=Fringe connection-like protein 1;
GN   Name=SLC35D3; Synonyms=FRCL1;
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
//
ID   S35E1_HUMAN             Reviewed;         410 AA.
AC   Q96K37; Q8NBQ2; Q96JV7;
DE   RecName: Full=Solute carrier family 35 member E1;
GN   Name=SLC35E1; ORFNames=PSEC0038;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35E2_HUMAN             Reviewed;         266 AA.
AC   P0CK97; B3KWR0; O75035; Q2TAY8; Q569F8; Q5CZA4; Q5QPR8; Q9Y3J8;
DE   RecName: Full=Solute carrier family 35 member E2;
GN   Name=SLC35E2;
//
ID   S35E3_HUMAN             Reviewed;         313 AA.
AC   Q7Z769; A8K0T0; Q0P5Y5; Q9P0V1;
DE   RecName: Full=Solute carrier family 35 member E3;
DE   AltName: Full=Bladder cancer-overexpressed gene 1 protein;
GN   Name=SLC35E3; Synonyms=BLOV1; ORFNames=UNQ3043/PRO9859;
//
ID   S35E4_HUMAN             Reviewed;         350 AA.
AC   Q6ICL7; Q567P0;
DE   RecName: Full=Solute carrier family 35 member E4;
GN   Name=SLC35E4;
//
ID   S35F1_HUMAN             Reviewed;         408 AA.
AC   Q5T1Q4; E1P564; Q1RMG1; Q4G0U9; Q4G167; Q6N007;
DE   RecName: Full=Solute carrier family 35 member F1;
GN   Name=SLC35F1; Synonyms=C6orf169;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35F2_HUMAN             Reviewed;         374 AA.
AC   Q8IXU6; Q14963; Q5JPA8; Q6ZRQ3; Q9H947;
DE   RecName: Full=Solute carrier family 35 member F2;
GN   Name=SLC35F2;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35F3_HUMAN             Reviewed;         421 AA.
AC   Q8IY50; Q5TDD6; Q8N9C9;
DE   RecName: Full=Solute carrier family 35 member F3;
GN   Name=SLC35F3;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35F4_HUMAN             Reviewed;         521 AA.
AC   A4IF30; A6NDQ3;
DE   RecName: Full=Solute carrier family 35 member F4;
GN   Name=SLC35F4; Synonyms=C14orf36;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35F5_HUMAN             Reviewed;         523 AA.
AC   Q8WV83; Q9H6P8; Q9H7D8;
DE   RecName: Full=Solute carrier family 35 member F5;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 3;
DE            Short=HCV NS5A-transactivated protein 3;
GN   Name=SLC35F5; Synonyms=NS5ATP3; ORFNames=UNQ2545/PRO6097;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35F6_HUMAN             Reviewed;         371 AA.
AC   Q8N357; D6W543; Q53GK2; Q8NBX6; Q9NWX0;
DE   RecName: Full=Solute carrier family 35 member F6;
DE   AltName: Full=ANT2-binding protein;
DE            Short=ANT2BP;
DE   AltName: Full=Transport and Golgi organization 9 homolog;
DE   Flags: Precursor;
GN   Name=SLC35F6; Synonyms=C2orf18; ORFNames=UNQ3047/PRO9863;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S35G2_HUMAN             Reviewed;         412 AA.
AC   Q8TBE7; B2RA80; D3DNE1; Q9BWN4; Q9H0S6;
DE   RecName: Full=Solute carrier family 35 member G2;
DE   AltName: Full=Transmembrane protein 22;
GN   Name=SLC35G2; Synonyms=TMEM22;
//
ID   S35G1_HUMAN             Reviewed;         365 AA.
AC   Q2M3R5; Q86YG5; Q8NBA5;
DE   RecName: Full=Solute carrier family 35 member G1;
DE   AltName: Full=Transmembrane protein 20;
GN   Name=SLC35G1; Synonyms=C10orf60, TMEM20;
//
ID   S35G3_HUMAN             Reviewed;         338 AA.
AC   Q8N808; B9EGE9;
DE   RecName: Full=Solute carrier family 35 member G3;
DE   AltName: Full=Acyl-malonyl-condensing enzyme 1;
DE   AltName: Full=Transmembrane protein 21A;
GN   Name=SLC35G3; Synonyms=AMAC1, TMEM21A;
//
ID   S35G4_HUMAN             Reviewed;         338 AA.
AC   P0C7Q5;
DE   RecName: Full=Putative solute carrier family 35 member G4;
DE   AltName: Full=Acyl-malonyl-condensing enzyme 1-like protein 1;
GN   Name=SLC35G4; Synonyms=AMAC1L1;
//
ID   S35G5_HUMAN             Reviewed;         338 AA.
AC   Q96KT7; A2RRL6;
DE   RecName: Full=Solute carrier family 35 member G5;
DE   AltName: Full=Acyl-malonyl-condensing enzyme 1-like protein 2;
GN   Name=SLC35G5; Synonyms=AMAC, AMAC1L2;
//
ID   S35G6_HUMAN             Reviewed;         338 AA.
AC   P0C7Q6;
DE   RecName: Full=Solute carrier family 35 member G6;
DE   AltName: Full=Acyl-malonyl-condensing enzyme 1-like protein 3;
DE   AltName: Full=Transmembrane protein 21B;
GN   Name=SLC35G6; Synonyms=AMAC1L3, TMEM21B;
//
ID   S36A1_HUMAN             Reviewed;         476 AA.
AC   Q7Z2H8; C9JI34; Q1LZ56; Q7Z7C0; Q86YK4; Q96M74;
DE   RecName: Full=Proton-coupled amino acid transporter 1;
DE            Short=Proton/amino acid transporter 1;
DE            Short=hPAT1;
DE   AltName: Full=Solute carrier family 36 member 1;
GN   Name=SLC36A1; Synonyms=PAT1;
DR   GuidetoPHARMACOLOGY; 1161; -.
DR   GO; GO:0015187; F:glycine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015180; F:L-alanine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015193; F:L-proline transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S36A2_HUMAN             Reviewed;         483 AA.
AC   Q495M3; Q495M4; Q495M6; Q6ZWK5; Q7Z6B5;
DE   RecName: Full=Proton-coupled amino acid transporter 2;
DE            Short=Proton/amino acid transporter 2;
DE   AltName: Full=Solute carrier family 36 member 2;
DE   AltName: Full=Tramdorin-1;
GN   Name=SLC36A2; Synonyms=PAT2, TRAMD1;
DR   GuidetoPHARMACOLOGY; 1162; -.
DR   GO; GO:0015187; F:glycine transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0005280; F:hydrogen:amino acid symporter activity; IEA:Ensembl.
DR   GO; GO:0015180; F:L-alanine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015193; F:L-proline transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035524; P:proline transmembrane transport; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S36A3_HUMAN             Reviewed;         470 AA.
AC   Q495N2; Q495N3; Q6ZMU7; Q6ZRU4; Q7Z6B4;
DE   RecName: Full=Proton-coupled amino acid transporter 3;
DE            Short=Proton/amino acid transporter 3;
DE   AltName: Full=Solute carrier family 36 member 3;
DE   AltName: Full=Tramdorin-2;
GN   Name=SLC36A3; Synonyms=PAT3, TRAMD2;
//
ID   S36A4_HUMAN             Reviewed;         504 AA.
AC   Q6YBV0; Q86X30; Q8IVM5; Q8N8S6;
DE   RecName: Full=Proton-coupled amino acid transporter 4;
DE            Short=Proton/amino acid transporter 4;
DE   AltName: Full=Solute carrier family 36 member 4;
GN   Name=SLC36A4; Synonyms=PAT4;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015808; P:L-alanine transport; IDA:UniProtKB.
DR   GO; GO:0015824; P:proline transport; IDA:UniProtKB.
DR   GO; GO:0015827; P:tryptophan transport; IDA:UniProtKB.
//
ID   S38A1_HUMAN             Reviewed;         487 AA.
AC   Q9H2H9; Q8NC61; Q8NCF8; Q96JX2; Q9H2Q2;
DE   RecName: Full=Sodium-coupled neutral amino acid transporter 1;
DE   AltName: Full=Amino acid transporter A1;
DE   AltName: Full=N-system amino acid transporter 2;
DE   AltName: Full=Solute carrier family 38 member 1;
DE   AltName: Full=System A amino acid transporter 1;
DE   AltName: Full=System N amino acid transporter 1;
GN   Name=SLC38A1; Synonyms=ATA1, NAT2, SAT1, SNAT1;
DR   GuidetoPHARMACOLOGY; 1169; -.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0005283; F:sodium:amino acid symporter activity; NAS:UniProtKB.
DR   GO; GO:0003333; P:amino acid transmembrane transport; NAS:GOC.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0001504; P:neurotransmitter uptake; TAS:Reactome.
DR   GO; GO:0015804; P:neutral amino acid transport; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S38A2_HUMAN             Reviewed;         506 AA.
AC   Q96QD8; Q6IA88; Q6ZMG2; Q9HAV3; Q9NVA8; Q9P2G5;
DE   RecName: Full=Sodium-coupled neutral amino acid transporter 2;
DE   AltName: Full=Amino acid transporter A2;
DE   AltName: Full=Protein 40-9-1;
DE   AltName: Full=Solute carrier family 38 member 2;
DE   AltName: Full=System A amino acid transporter 2;
DE   AltName: Full=System A transporter 1;
DE   AltName: Full=System N amino acid transporter 2;
GN   Name=SLC38A2; Synonyms=ATA2, KIAA1382, SAT2, SNAT2;
DR   GuidetoPHARMACOLOGY; 1170; -.
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S38A4_HUMAN             Reviewed;         547 AA.
AC   Q969I6; A8K553;
DE   RecName: Full=Sodium-coupled neutral amino acid transporter 4;
DE   AltName: Full=Amino acid transporter A3;
DE   AltName: Full=Na(+)-coupled neutral amino acid transporter 4;
DE   AltName: Full=Solute carrier family 38 member 4;
DE   AltName: Full=System A amino acid transporter 3;
DE   AltName: Full=System N amino acid transporter 3;
GN   Name=SLC38A4; Synonyms=ATA3, NAT3, SNAT4;
DR   GuidetoPHARMACOLOGY; 1171; -.
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S38A3_HUMAN             Reviewed;         504 AA.
AC   Q99624; B2R8Q0; Q6IB34;
DE   RecName: Full=Sodium-coupled neutral amino acid transporter 3;
DE   AltName: Full=N-system amino acid transporter 1;
DE   AltName: Full=Na(+)-coupled neutral amino acid transporter 3;
DE   AltName: Full=Solute carrier family 38 member 3;
DE   AltName: Full=System N amino acid transporter 1;
GN   Name=SLC38A3; Synonyms=G17, NAT1, SN1, SNAT3;
DR   GuidetoPHARMACOLOGY; 1172; -.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015180; F:L-alanine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015182; F:L-asparagine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005290; F:L-histidine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006867; P:asparagine transport; IDA:UniProtKB.
DR   GO; GO:0006868; P:glutamine transport; IDA:UniProtKB.
DR   GO; GO:0015817; P:histidine transport; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015808; P:L-alanine transport; IDA:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S38A5_HUMAN             Reviewed;         472 AA.
AC   Q8WUX1; B3KT20; B5MDE6; B7WPJ9; Q6PIW9; Q8WYU2; Q96PQ4;
DE   RecName: Full=Sodium-coupled neutral amino acid transporter 5;
DE   AltName: Full=Solute carrier family 38 member 5;
DE   AltName: Full=System N transporter 2;
GN   Name=SLC38A5; Synonyms=JM24, SN2, SNAT5; ORFNames=PP7194;
DR   GuidetoPHARMACOLOGY; 1173; -.
DR   GO; GO:0015187; F:glycine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S38A6_HUMAN             Reviewed;         456 AA.
AC   Q8IZM9; C9JWA6; Q86SY5;
DE   RecName: Full=Probable sodium-coupled neutral amino acid transporter 6;
DE   AltName: Full=N-system amino acid transporter 1;
DE            Short=NAT-1;
DE   AltName: Full=Na(+)-coupled neutral amino acid transporter 6;
DE   AltName: Full=Solute carrier family 38 member 6;
GN   Name=SLC38A6; Synonyms=NAT1, SNAT6;
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   S38A7_HUMAN             Reviewed;         462 AA.
AC   Q9NVC3; Q53GJ9; Q9H9I5;
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 7;
DE   AltName: Full=Solute carrier family 38 member 7;
GN   Name=SLC38A7; Synonyms=SNAT7;
DR   GO; GO:0015180; F:L-alanine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0015182; F:L-asparagine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015183; F:L-aspartate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005290; F:L-histidine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015190; F:L-leucine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015191; F:L-methionine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015194; F:L-serine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:1902475; P:L-alpha-amino acid transmembrane transport; ISS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; ISS:UniProtKB.
//
ID   S38A8_HUMAN             Reviewed;         435 AA.
AC   A6NNN8;
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 8;
DE   AltName: Full=Solute carrier family 38 member 8;
GN   Name=SLC38A8;
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   S38A9_HUMAN             Reviewed;         561 AA.
AC   Q8NBW4; B3KXV1; B7Z7D0; Q0P5S0; Q6MZJ8;
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 9;
DE   AltName: Full=Solute carrier family 38 member 9;
GN   Name=SLC38A9;
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   S38AA_HUMAN             Reviewed;        1119 AA.
AC   Q9HBR0; Q6ZRC5; Q8NA99; Q96C66;
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 10;
DE   AltName: Full=Solute carrier family 38 member 10;
GN   Name=SLC38A10; ORFNames=PP1744;
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   S38AB_HUMAN             Reviewed;         406 AA.
AC   Q08AI6; B4DF99; Q8N887;
DE   RecName: Full=Putative sodium-coupled neutral amino acid transporter 11;
DE   AltName: Full=Solute carrier family 38 member 11;
GN   Name=SLC38A11; Synonyms=AVT2;
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   S39A1_HUMAN             Reviewed;         324 AA.
AC   Q9NY26; Q5T4K1; Q8N2H7; Q9BTV0; Q9UBI7; Q9Y2Z7; Q9Y380;
DE   RecName: Full=Zinc transporter ZIP1;
DE   AltName: Full=Solute carrier family 39 member 1;
DE   AltName: Full=Zinc-iron-regulated transporter-like;
DE   AltName: Full=Zrt- and Irt-like protein 1;
DE            Short=ZIP-1;
DE            Short=hZIP1;
GN   Name=SLC39A1; Synonyms=IRT1, ZIP1, ZIRTL; ORFNames=CGI-08, CGI-71;
DR   GO; GO:0022890; F:inorganic cation transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006812; P:cation transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IMP:UniProtKB.
//
ID   S39A2_HUMAN             Reviewed;         309 AA.
AC   Q9NP94; B2RC76; G3V5X2; Q4QQJ1; Q4V9S4; Q96JT6; Q9UD20;
DE   RecName: Full=Zinc transporter ZIP2;
DE   AltName: Full=6A1;
DE   AltName: Full=Eti-1;
DE   AltName: Full=Solute carrier family 39 member 2;
DE   AltName: Full=Zrt- and Irt-like protein 2;
DE            Short=ZIP-2;
DE            Short=hZIP2;
GN   Name=SLC39A2; Synonyms=ZIP2;
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; TAS:ProtInc.
//
ID   S39A3_HUMAN             Reviewed;         314 AA.
AC   Q9BRY0; B3KMJ3; Q8WUG1;
DE   RecName: Full=Zinc transporter ZIP3;
DE   AltName: Full=Solute carrier family 39 member 3;
DE   AltName: Full=Zrt- and Irt-like protein 3;
DE            Short=ZIP-3;
GN   Name=SLC39A3; Synonyms=ZIP3;
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S39A4_HUMAN             Reviewed;         647 AA.
AC   Q6P5W5; Q7L5S5; Q9H6T8; Q9NXC4;
DE   RecName: Full=Zinc transporter ZIP4;
DE   AltName: Full=Solute carrier family 39 member 4;
DE   AltName: Full=Zrt- and Irt-like protein 4;
DE            Short=ZIP-4;
DE   Flags: Precursor;
GN   Name=SLC39A4; Synonyms=ZIP4;
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0034224; P:cellular response to zinc ion starvation; IEA:Ensembl.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S39A5_HUMAN             Reviewed;         540 AA.
AC   Q6ZMH5; B2R808; Q8N6Y3;
DE   RecName: Full=Zinc transporter ZIP5;
DE   AltName: Full=Solute carrier family 39 member 5;
DE   AltName: Full=Zrt- and Irt-like protein 5;
DE            Short=ZIP-5;
DE   Flags: Precursor;
GN   Name=SLC39A5; Synonyms=ZIP5;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0034224; P:cellular response to zinc ion starvation; IEA:Ensembl.
DR   GO; GO:0070315; P:G1 to G0 transition involved in cell differentiation; ISS:UniProtKB.
DR   GO; GO:0061351; P:neural precursor cell proliferation; ISS:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   S39A6_HUMAN             Reviewed;         755 AA.
AC   Q13433; B4DR49; B4E224; Q8IXR3; Q96HP5;
DE   RecName: Full=Zinc transporter ZIP6;
DE   AltName: Full=Estrogen-regulated protein LIV-1;
DE   AltName: Full=Solute carrier family 39 member 6;
DE   AltName: Full=Zrt- and Irt-like protein 6;
DE            Short=ZIP-6;
DE   Flags: Precursor;
GN   Name=SLC39A6; Synonyms=LIV1, ZIP6;
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0071578; P:zinc ion transmembrane import; IDA:BHF-UCL.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IMP:UniProtKB.
//
ID   S39AB_HUMAN             Reviewed;         342 AA.
AC   Q8N1S5; B2R8H7; Q8WZ81;
DE   RecName: Full=Zinc transporter ZIP11;
DE   AltName: Full=Solute carrier family 39 member 11;
DE   AltName: Full=Zrt- and Irt-like protein 11;
DE            Short=ZIP-11;
GN   Name=SLC39A11; Synonyms=C17orf26, ZIP11;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   S39AA_HUMAN             Reviewed;         831 AA.
AC   Q9ULF5; A8K5C6; Q3MJA4; Q68CR5; Q6DKH6; Q9Y3Z1;
DE   RecName: Full=Zinc transporter ZIP10;
DE   AltName: Full=Solute carrier family 39 member 10;
DE   AltName: Full=Zrt- and Irt-like protein 10;
DE            Short=ZIP-10;
DE   Flags: Precursor;
GN   Name=SLC39A10; Synonyms=KIAA1265, ZIP10;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   S39A9_HUMAN             Reviewed;         307 AA.
AC   Q9NUM3; G3V5J8; Q53HN3; Q5MJQ0; Q6P2Q1; Q86WY2;
DE   RecName: Full=Zinc transporter ZIP9;
DE   AltName: Full=Solute carrier family 39 member 9;
DE   AltName: Full=Zrt- and Irt-like protein 9;
DE            Short=ZIP-9;
GN   Name=SLC39A9; Synonyms=ZIP9; ORFNames=UNQ714/PRO1377;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   S39A8_HUMAN             Reviewed;         460 AA.
AC   Q9C0K1; B4E2H3; Q96SM9; Q9BVC0; Q9NSA4;
DE   RecName: Full=Zinc transporter ZIP8;
DE   AltName: Full=BCG-induced integral membrane protein in monocyte clone 103 protein;
DE   AltName: Full=LIV-1 subfamily of ZIP zinc transporter 6;
DE            Short=LZT-Hs6;
DE   AltName: Full=Solute carrier family 39 member 8;
DE   AltName: Full=Zrt- and Irt-like protein 8;
DE            Short=ZIP-8;
GN   Name=SLC39A8; Synonyms=BIGM103, ZIP8; ORFNames=PP3105;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; IMP:UniProtKB.
//
ID   S39A7_HUMAN             Reviewed;         469 AA.
AC   Q92504; B0UXF6; Q5STP8; Q9UIQ0;
DE   RecName: Full=Zinc transporter SLC39A7;
DE   AltName: Full=Histidine-rich membrane protein Ke4;
DE   AltName: Full=Really interesting new gene 5 protein;
DE   AltName: Full=Solute carrier family 39 member 7;
DE   AltName: Full=Zrt-, Irt-like protein 7;
DE            Short=ZIP7;
GN   Name=SLC39A7; Synonyms=HKE4, RING5;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   S39AC_HUMAN             Reviewed;         691 AA.
AC   Q504Y0; B7ZL35; C9JJL4; Q49AN8; Q4G0L3; Q5VWV8; Q5VWV9; Q6NZY5;
AC   Q96NN4;
DE   RecName: Full=Zinc transporter ZIP12;
DE   AltName: Full=LIV-1 subfamily of ZIP zinc transporter 8;
DE            Short=LZT-Hs8;
DE   AltName: Full=Solute carrier family 39 member 12;
DE   AltName: Full=Zrt- and Irt-like protein 12;
DE            Short=ZIP-12;
GN   Name=SLC39A12; Synonyms=ZIP12;
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   S39AD_HUMAN             Reviewed;         371 AA.
AC   Q96H72; D3DQR6; D3DQR7; E9PLY1; E9PQV3; Q659D9; Q8N7C9; Q8WV10;
DE   RecName: Full=Zinc transporter ZIP13;
DE   AltName: Full=LIV-1 subfamily of ZIP zinc transporter 9;
DE            Short=LZT-Hs9;
DE   AltName: Full=Solute carrier family 39 member 13;
DE   AltName: Full=Zrt- and Irt-like protein 13;
DE            Short=ZIP-13;
GN   Name=SLC39A13; Synonyms=ZIP13;
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0061448; P:connective tissue development; IMP:BHF-UCL.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IDA:BHF-UCL.
//
ID   S39AE_HUMAN             Reviewed;         492 AA.
AC   Q15043; A6NH98; B4DIW3; B6EU88; D3DSR4; Q6ZME8; Q96BB3;
DE   RecName: Full=Zinc transporter ZIP14;
DE   AltName: Full=LIV-1 subfamily of ZIP zinc transporter 4;
DE            Short=LZT-Hs4;
DE   AltName: Full=Solute carrier family 39 member 14;
DE   AltName: Full=Zrt- and Irt-like protein 14;
DE            Short=ZIP-14;
DE   Flags: Precursor;
GN   Name=SLC39A14; Synonyms=KIAA0062, ZIP14;
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0071578; P:zinc ion transmembrane import; IDA:BHF-UCL.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IMP:UniProtKB.
//
ID   S3TC2_HUMAN             Reviewed;        1288 AA.
AC   Q8TF17; B3KWE5; Q14CC0; Q14CF5; Q9H8I5;
DE   RecName: Full=SH3 domain and tetratricopeptide repeat-containing protein 2;
GN   Name=SH3TC2; Synonyms=KIAA1985; ORFNames=PP12494;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; IEA:Ensembl.
DR   GO; GO:1901184; P:regulation of ERBB signaling pathway; IEA:Ensembl.
DR   GO; GO:0033157; P:regulation of intracellular protein transport; IEA:Ensembl.
//
ID   S3TC1_HUMAN             Reviewed;        1336 AA.
AC   Q8TE82; Q4W5G5;
DE   RecName: Full=SH3 domain and tetratricopeptide repeat-containing protein 1;
GN   Name=SH3TC1;
//
ID   S40A1_HUMAN             Reviewed;         571 AA.
AC   Q9NP59; Q6FI62; Q7Z4F8; Q8IVB2; Q9NRL0;
DE   RecName: Full=Solute carrier family 40 member 1;
DE   AltName: Full=Ferroportin-1;
DE   AltName: Full=Iron-regulated transporter 1;
GN   Name=SLC40A1; Synonyms=FPN1, IREG1, SLC11A3; ORFNames=MSTP079;
DR   GO; GO:0005381; F:iron ion transmembrane transporter activity; IMP:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0003158; P:endothelium development; IEA:Ensembl.
DR   GO; GO:0034755; P:iron ion transmembrane transport; IMP:BHF-UCL.
DR   GO; GO:0002260; P:lymphocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0060586; P:multicellular organismal iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0060345; P:spleen trabecula formation; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S41A1_HUMAN             Reviewed;         513 AA.
AC   Q8IVJ1; Q63HJ4; Q658Z5; Q659A4; Q6MZK2;
DE   RecName: Full=Solute carrier family 41 member 1;
GN   Name=SLC41A1;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S41A2_HUMAN             Reviewed;         573 AA.
AC   Q96JW4; Q3KP68; Q9H0E5;
DE   RecName: Full=Solute carrier family 41 member 2;
GN   Name=SLC41A2;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S41A3_HUMAN             Reviewed;         507 AA.
AC   Q96GZ6; A6ND60; B3KSD9; B7Z4Y2; C9JE96; E7ENY4; Q8N342; Q8NB27;
AC   Q9H9I6; Q9HAB1; Q9NX30;
DE   RecName: Full=Solute carrier family 41 member 3;
GN   Name=SLC41A3;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
//
ID   S43A3_HUMAN             Reviewed;         491 AA.
AC   Q8NBI5; Q9NSS4;
DE   RecName: Full=Solute carrier family 43 member 3;
DE   AltName: Full=Protein FOAP-13;
GN   Name=SLC43A3; ORFNames=PSEC0252;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S45A1_HUMAN             Reviewed;         748 AA.
AC   Q9Y2W3; Q5VY46; Q5VY49;
DE   RecName: Full=Proton-associated sugar transporter A;
DE            Short=PAST-A;
DE   AltName: Full=Deleted in neuroblastoma 5 protein;
DE            Short=DNb-5;
DE   AltName: Full=Solute carrier family 45 member 1;
GN   Name=SLC45A1; Synonyms=DNB5;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
//
ID   S45A2_HUMAN             Reviewed;         530 AA.
AC   Q9UMX9; Q6P2P0; Q9BTM3;
DE   RecName: Full=Membrane-associated transporter protein;
DE   AltName: Full=Melanoma antigen AIM1;
DE            Short=Protein AIM-1;
DE   AltName: Full=Solute carrier family 45 member 2;
GN   Name=SLC45A2; Synonyms=AIM1, MATP;
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   S45A3_HUMAN             Reviewed;         553 AA.
AC   Q96JT2;
DE   RecName: Full=Solute carrier family 45 member 3;
DE   AltName: Full=Prostate cancer-associated protein 6;
DE   AltName: Full=Prostein;
GN   Name=SLC45A3; Synonyms=PCANAP6, PRST;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S45A4_HUMAN             Reviewed;         768 AA.
AC   Q5BKX6; Q6ZRI2; Q9ULU3;
DE   RecName: Full=Solute carrier family 45 member 4;
GN   Name=SLC45A4; Synonyms=KIAA1126;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   S46A3_HUMAN             Reviewed;         461 AA.
AC   Q7Z3Q1; Q3ZCV8; Q6NUK5; Q6P9B3; Q6ZVG5; Q96QA1;
DE   RecName: Full=Solute carrier family 46 member 3;
DE   Flags: Precursor;
GN   Name=SLC46A3; ORFNames=FKSG16;
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   S47A1_HUMAN             Reviewed;         570 AA.
AC   Q96FL8; Q53HF5; Q6PD77; Q86VL4; Q9NVA3;
DE   RecName: Full=Multidrug and toxin extrusion protein 1;
DE            Short=MATE-1;
DE            Short=hMATE-1;
DE   AltName: Full=Solute carrier family 47 member 1;
GN   Name=SLC47A1; Synonyms=MATE1;
DR   GuidetoPHARMACOLOGY; 1216; -.
DR   GO; GO:0015238; F:drug transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005451; F:monovalent cation:proton antiporter activity; IEA:Ensembl.
DR   GO; GO:0015695; P:organic cation transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S47A2_HUMAN             Reviewed;         602 AA.
AC   Q86VL8; A0JBX9; A0P8Z7; Q63HJ9; Q8IV44; Q96NA1;
DE   RecName: Full=Multidrug and toxin extrusion protein 2;
DE            Short=MATE-2;
DE            Short=hMATE-2;
DE   AltName: Full=Kidney-specific H(+)/organic cation antiporter;
DE   AltName: Full=Solute carrier family 47 member 2;
GN   Name=SLC47A2; Synonyms=MATE2;
DR   GuidetoPHARMACOLOGY; 1217; -.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0015238; F:drug transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S4A10_HUMAN             Reviewed;        1118 AA.
AC   Q6U841; B7Z1R0; B7Z2J0; B7ZLC5; B9EG69; F8W675; Q4ZFX6; Q8TCP2;
AC   Q9HCQ6;
DE   RecName: Full=Sodium-driven chloride bicarbonate exchanger;
DE   AltName: Full=Solute carrier family 4 member 10;
GN   Name=SLC4A10; Synonyms=NCBE;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015701; P:bicarbonate transport; NAS:UniProtKB.
DR   GO; GO:0006821; P:chloride transport; NAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S4A11_HUMAN             Reviewed;         891 AA.
AC   Q8NBS3; B4DKC8; B4DKX9; G3V1M3; Q2TB62; Q2TB63; Q9BXF4; Q9NTW9;
DE   RecName: Full=Sodium bicarbonate transporter-like protein 11;
DE   AltName: Full=Bicarbonate transporter-related protein 1;
DE   AltName: Full=Sodium borate cotransporter 1;
DE            Short=NaBC1;
DE   AltName: Full=Solute carrier family 4 member 11;
GN   Name=SLC4A11; Synonyms=BTR1;
DR   GO; GO:0015106; F:bicarbonate transmembrane transporter activity; IDA:HGNC.
DR   GO; GO:0046715; F:borate transmembrane transporter activity; IDA:HGNC.
DR   GO; GO:0015252; F:hydrogen ion channel activity; IDA:HGNC.
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0005272; F:sodium channel activity; IDA:HGNC.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0015701; P:bicarbonate transport; IDA:HGNC.
DR   GO; GO:0035445; P:borate transmembrane transport; IDA:GOC.
DR   GO; GO:0046713; P:borate transport; IDA:HGNC.
DR   GO; GO:0030003; P:cellular cation homeostasis; IDA:HGNC.
DR   GO; GO:0042044; P:fluid transport; ISS:UniProtKB.
DR   GO; GO:0015992; P:proton transport; IDA:HGNC.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006814; P:sodium ion transport; IDA:HGNC.
//
ID   S4A4_HUMAN              Reviewed;        1079 AA.
AC   Q9Y6R1; C4B714; O15153; Q8NEJ2; Q9H262; Q9NRZ1; Q9UIC0; Q9UIC1;
AC   Q9UP50;
DE   RecName: Full=Electrogenic sodium bicarbonate cotransporter 1;
DE            Short=Sodium bicarbonate cotransporter;
DE   AltName: Full=Na(+)/HCO3(-) cotransporter;
DE   AltName: Full=Solute carrier family 4 member 4;
DE   AltName: Full=kNBC1;
GN   Name=SLC4A4; Synonyms=NBC, NBC1, NBCE1;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:DFLAT.
DR   GO; GO:0008510; F:sodium:bicarbonate symporter activity; TAS:ProtInc.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S4A5_HUMAN              Reviewed;        1137 AA.
AC   Q9BY07; Q32MA7; Q59EQ9; Q8WXD3; Q8WXD7; Q96DS7; Q96DS8; Q9HBU5;
DE   RecName: Full=Electrogenic sodium bicarbonate cotransporter 4;
DE   AltName: Full=NBCe2;
DE   AltName: Full=Solute carrier family 4 member 5;
GN   Name=SLC4A5; Synonyms=NBC4;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0008510; F:sodium:bicarbonate symporter activity; NAS:UniProtKB.
DR   GO; GO:0015701; P:bicarbonate transport; NAS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S4A7_HUMAN              Reviewed;        1214 AA.
AC   Q9Y6M7; A6NIA8; B2CI53; B5M449; B5M451; B5M452; B5M453; B6DY52;
AC   B6DY53; C9JST9; D3K174; D3K175; O60350; Q6AHZ9; Q9HC88; Q9UIB9;
DE   RecName: Full=Sodium bicarbonate cotransporter 3;
DE   AltName: Full=Electroneutral Na/HCO(3) cotransporter;
DE   AltName: Full=Sodium bicarbonate cotransporter 2;
DE   AltName: Full=Sodium bicarbonate cotransporter 2b;
DE            Short=Bicarbonate transporter;
DE   AltName: Full=Solute carrier family 4 member 7;
GN   Name=SLC4A7; Synonyms=BT, NBC2, NBC2B, NBC3, NBCn1, SBC2, SLC4A6;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0008510; F:sodium:bicarbonate symporter activity; NAS:UniProtKB.
DR   GO; GO:0060117; P:auditory receptor cell development; IEA:Ensembl.
DR   GO; GO:0015701; P:bicarbonate transport; NAS:UniProtKB.
DR   GO; GO:0021747; P:cochlear nucleus development; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0046666; P:retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S4A8_HUMAN              Reviewed;        1093 AA.
AC   Q2Y0W8; A0MMZ1; E7EML0; F5H7F5; O94843; O95233; Q004B4; Q8N3U2;
AC   Q8TC60; Q9UKX8;
DE   RecName: Full=Electroneutral sodium bicarbonate exchanger 1;
DE   AltName: Full=Electroneutral Na(+)-driven Cl-HCO3 exchanger;
DE   AltName: Full=Solute carrier family 4 member 8;
DE   AltName: Full=k-NBC3;
GN   Name=SLC4A8; Synonyms=KIAA0739, NBC, NBC3, NDCBE1;
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0015701; P:bicarbonate transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S52A1_HUMAN             Reviewed;         448 AA.
AC   Q9NWF4; B5MEV1; B5MEV2; Q6P9E0; Q86UT0;
DE   RecName: Full=Solute carrier family 52, riboflavin transporter, member 1;
DE   AltName: Full=Porcine endogenous retrovirus A receptor 2;
DE            Short=PERV-A receptor 2;
DE   AltName: Full=Protein GPR172B;
DE   AltName: Full=Riboflavin transporter 1;
DE            Short=hRFT1;
GN   Name=SLC52A1; Synonyms=GPR172B, PAR2, RFT1;
DR   GO; GO:0032217; F:riboflavin transporter activity; IDA:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0032218; P:riboflavin transport; IDA:UniProtKB.
//
ID   S52A2_HUMAN             Reviewed;         445 AA.
AC   Q9HAB3; A8K6B6; D3DWL8; G1UCY1; Q86UT1;
DE   RecName: Full=Solute carrier family 52, riboflavin transporter, member 2;
DE   AltName: Full=Porcine endogenous retrovirus A receptor 1;
DE            Short=PERV-A receptor 1;
DE   AltName: Full=Protein GPR172A;
DE   AltName: Full=Riboflavin transporter 3;
DE            Short=hRFT3;
GN   Name=SLC52A2; Synonyms=GPR172A, PAR1, RFT3;
DR   GO; GO:0032217; F:riboflavin transporter activity; IDA:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0032218; P:riboflavin transport; IDA:UniProtKB.
//
ID   S52A3_HUMAN             Reviewed;         469 AA.
AC   Q9NQ40; A8K6P1; Q5W1A0; Q5W1A1; Q8NCL7; Q96GD5;
DE   RecName: Full=Solute carrier family 52, riboflavin transporter, member 3;
DE   AltName: Full=Riboflavin transporter 2;
DE            Short=hRFT2;
GN   Name=SLC52A3; Synonyms=C20orf54, RFT2;
DR   GO; GO:0032217; F:riboflavin transporter activity; IDA:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006771; P:riboflavin metabolic process; TAS:Reactome.
DR   GO; GO:0032218; P:riboflavin transport; IDA:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   S5A1_HUMAN              Reviewed;         259 AA.
AC   P18405; B2R7Q1; Q9UHY4; Q9UP36; Q9UP37;
DE   RecName: Full=3-oxo-5-alpha-steroid 4-dehydrogenase 1;
DE            EC=1.3.1.22;
DE   AltName: Full=SR type 1;
DE   AltName: Full=Steroid 5-alpha-reductase 1;
DE            Short=S5AR 1;
GN   Name=SRD5A1;
DR   GO; GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0047751; F:cholestenone 5-alpha-reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007530; P:sex determination; NAS:ProtInc.
DR   GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   S5A2_HUMAN              Reviewed;         254 AA.
AC   P31213; B2RE87; Q2M1R4; Q9BYE6;
DE   RecName: Full=3-oxo-5-alpha-steroid 4-dehydrogenase 2;
DE            EC=1.3.1.22;
DE   AltName: Full=5 alpha-SR2;
DE   AltName: Full=SR type 2;
DE   AltName: Full=Steroid 5-alpha-reductase 2;
DE            Short=S5AR 2;
DE   AltName: Full=Type II 5-alpha reductase;
GN   Name=SRD5A2;
DR   GuidetoPHARMACOLOGY; 2633; -.
DR   GO; GO:0003865; F:3-oxo-5-alpha-steroid 4-dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0047751; F:cholestenone 5-alpha-reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009917; F:sterol 5-alpha reductase activity; IDA:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; TAS:Reactome.
DR   GO; GO:0008209; P:androgen metabolic process; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   S61A1_HUMAN             Reviewed;         476 AA.
AC   P61619; P38378; P57726; Q5JPF8; Q8N0Z4; Q8N3U3; Q8NC71; Q9BU16;
AC   Q9Y2R3;
DE   RecName: Full=Protein transport protein Sec61 subunit alpha isoform 1;
DE            Short=Sec61 alpha-1;
GN   Name=SEC61A1; Synonyms=SEC61A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043022; F:ribosome binding; ISS:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0016049; P:cell growth; IMP:MGI.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IMP:MGI.
DR   GO; GO:0006620; P:posttranslational protein targeting to membrane; IMP:MGI.
DR   GO; GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IMP:MGI.
//
ID   S61A2_HUMAN             Reviewed;         476 AA.
AC   Q9H9S3; A8K8D0; B4DX72; F8W773;
DE   RecName: Full=Protein transport protein Sec61 subunit alpha isoform 2;
DE            Short=Sec61 alpha-2;
GN   Name=SEC61A2;
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   S6A11_HUMAN             Reviewed;         632 AA.
AC   P48066; B2R6U6;
DE   RecName: Full=Sodium- and chloride-dependent GABA transporter 3;
DE            Short=GAT-3;
DE   AltName: Full=Solute carrier family 6 member 11;
GN   Name=SLC6A11; Synonyms=GABT3, GAT3;
DR   GO; GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0042165; F:neurotransmitter binding; IEA:Ensembl.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S6A12_HUMAN             Reviewed;         614 AA.
AC   P48065; A0AV52; B2R992; D3DUN8;
DE   RecName: Full=Sodium- and chloride-dependent betaine transporter;
DE   AltName: Full=BGT-1;
DE   AltName: Full=Na(+)/Cl(-) betaine/GABA transporter;
DE   AltName: Full=Solute carrier family 6 member 12;
GN   Name=SLC6A12;
DR   GuidetoPHARMACOLOGY; 932; -.
DR   GO; GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0071474; P:cellular hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0009992; P:cellular water homeostasis; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S6A13_HUMAN             Reviewed;         602 AA.
AC   Q9NSD5; B4DJL1; Q8TCC2; Q8WW56;
DE   RecName: Full=Sodium- and chloride-dependent GABA transporter 2;
DE            Short=GAT-2;
DE   AltName: Full=Solute carrier family 6 member 13;
GN   Name=SLC6A13; Synonyms=GAT2;
DR   GuidetoPHARMACOLOGY; 930; -.
DR   GO; GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S6A14_HUMAN             Reviewed;         642 AA.
AC   Q9UN76; Q5H942;
DE   RecName: Full=Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+);
DE   AltName: Full=Amino acid transporter ATB0+;
DE   AltName: Full=Solute carrier family 6 member 14;
GN   Name=SLC6A14;
DR   GuidetoPHARMACOLOGY; 937; -.
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0003333; P:amino acid transmembrane transport; TAS:GOC.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   S6A15_HUMAN             Reviewed;         730 AA.
AC   Q9H2J7; A8K592; B7Z2P7; E7ESJ5; Q9H9F5;
DE   RecName: Full=Sodium-dependent neutral amino acid transporter B(0)AT2;
DE   AltName: Full=Sodium- and chloride-dependent neurotransmitter transporter NTT73;
DE   AltName: Full=Sodium-coupled branched-chain amino-acid transporter 1;
DE   AltName: Full=Solute carrier family 6 member 15;
DE   AltName: Full=Transporter v7-3;
GN   Name=SLC6A15; Synonyms=B0AT2, NTT73, SBAT1;
DR   GO; GO:0005326; F:neurotransmitter transporter activity; NAS:UniProtKB.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0005298; F:proline:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015820; P:leucine transport; ISS:UniProtKB.
DR   GO; GO:0006836; P:neurotransmitter transport; NAS:UniProtKB.
DR   GO; GO:0015804; P:neutral amino acid transport; IDA:UniProtKB.
DR   GO; GO:0015824; P:proline transport; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S6A16_HUMAN             Reviewed;         736 AA.
AC   Q9GZN6; Q9Y5I9;
DE   RecName: Full=Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5;
DE   AltName: Full=Solute carrier family 6 member 16;
GN   Name=SLC6A16; Synonyms=NTT5;
DR   GO; GO:0005326; F:neurotransmitter transporter activity; NAS:UniProtKB.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0006836; P:neurotransmitter transport; NAS:UniProtKB.
//
ID   S6A17_HUMAN             Reviewed;         727 AA.
AC   Q9H1V8; A6NEA8; A8K1R7; B9EIR5; Q5T5Q9;
DE   RecName: Full=Sodium-dependent neutral amino acid transporter SLC6A17;
DE   AltName: Full=Sodium-dependent neurotransmitter transporter NTT4;
DE   AltName: Full=Solute carrier family 6 member 17;
GN   Name=SLC6A17; Synonyms=NTT4;
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0032328; P:alanine transport; ISS:UniProtKB.
DR   GO; GO:0015816; P:glycine transport; ISS:UniProtKB.
DR   GO; GO:0015820; P:leucine transport; ISS:UniProtKB.
DR   GO; GO:0015804; P:neutral amino acid transport; ISS:UniProtKB.
DR   GO; GO:0015824; P:proline transport; ISS:UniProtKB.
//
ID   S6A18_HUMAN             Reviewed;         628 AA.
AC   Q96N87;
DE   RecName: Full=Sodium-dependent neutral amino acid transporter B(0)AT3;
DE   AltName: Full=Sodium- and chloride-dependent transporter XTRP2;
DE   AltName: Full=Solute carrier family 6 member 18;
DE   AltName: Full=System B(0) neutral amino acid transporter AT3;
GN   Name=SLC6A18; Synonyms=XTRP2;
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S6A19_HUMAN             Reviewed;         634 AA.
AC   Q695T7; A8K446;
DE   RecName: Full=Sodium-dependent neutral amino acid transporter B(0)AT1;
DE   AltName: Full=Solute carrier family 6 member 19;
DE   AltName: Full=System B(0) neutral amino acid transporter AT1;
GN   Name=SLC6A19; Synonyms=B0AT1;
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0015175; F:neutral amino acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S6A20_HUMAN             Reviewed;         592 AA.
AC   Q9NP91; A1A4F2; O75590; Q8TF10; Q9NPQ2; Q9NQ77;
DE   RecName: Full=Sodium- and chloride-dependent transporter XTRP3;
DE   AltName: Full=Sodium/imino-acid transporter 1;
DE   AltName: Full=Solute carrier family 6 member 20;
DE   AltName: Full=Transporter rB21A homolog;
GN   Name=SLC6A20; Synonyms=SIT1, XT3, XTRP3;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; IDA:UniProtKB.
DR   GO; GO:0015816; P:glycine transport; IMP:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015824; P:proline transport; IMP:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   S6OS1_HUMAN             Reviewed;         587 AA.
AC   Q8N1H7; Q08AQ4;
DE   RecName: Full=Protein SIX6OS1;
DE   AltName: Full=Six6 opposite strand transcript 1;
GN   Name=SIX6OS1; Synonyms=C14orf39;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
//
ID   S7A13_HUMAN             Reviewed;         470 AA.
AC   Q8TCU3; Q05C37; Q08AH9; Q96N84;
DE   RecName: Full=Solute carrier family 7 member 13;
DE   AltName: Full=Sodium-independent aspartate/glutamate transporter 1;
DE   AltName: Full=X-amino acid transporter 2;
GN   Name=SLC7A13; Synonyms=AGT1, XAT2;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
//
ID   S7A14_HUMAN             Reviewed;         771 AA.
AC   Q8TBB6; B3KV33; Q9HCF9;
DE   RecName: Full=Probable cationic amino acid transporter;
DE   AltName: Full=Solute carrier family 7 member 14;
GN   Name=SLC7A14; Synonyms=KIAA1613;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   S7A6O_HUMAN             Reviewed;         309 AA.
AC   Q96CW6; Q8TCZ3; Q9H8R8;
DE   RecName: Full=Probable RNA polymerase II nuclear localization protein SLC7A6OS;
DE   AltName: Full=ADAMS proteinase-related protein;
DE   AltName: Full=Solute carrier family 7 member 6 opposite strand transcript;
GN   Name=SLC7A6OS;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SAA1_HUMAN              Reviewed;         122 AA.
AC   P0DJI8; P02735; P02736; P02737; Q16730; Q16834; Q16835; Q16879;
AC   Q3KRB3; Q6FG67; Q96QN0; Q9UCK9; Q9UCL0;
DE   RecName: Full=Serum amyloid A-1 protein;
DE            Short=SAA;
DE   Contains:
DE     RecName: Full=Amyloid protein A;
DE     AltName: Full=Amyloid fibril protein AA;
DE   Contains:
DE     RecName: Full=Serum amyloid protein A(2-104);
DE   Contains:
DE     RecName: Full=Serum amyloid protein A(3-104);
DE   Contains:
DE     RecName: Full=Serum amyloid protein A(2-103);
DE   Contains:
DE     RecName: Full=Serum amyloid protein A(2-102);
DE   Contains:
DE     RecName: Full=Serum amyloid protein A(4-101);
DE   Flags: Precursor;
GN   Name=SAA1;
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IDA:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048246; P:macrophage chemotaxis; IDA:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; NAS:UniProtKB.
DR   GO; GO:0030593; P:neutrophil chemotaxis; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0050716; P:positive regulation of interleukin-1 secretion; NAS:UniProtKB.
DR   GO; GO:0050708; P:regulation of protein secretion; NAS:UniProtKB.
//
ID   SAA2_HUMAN              Reviewed;         122 AA.
AC   P0DJI9; G3XAK9; P02735; P02736; P02737; Q16730; Q16834; Q16835;
AC   Q16879; Q3KRB3; Q6FG67; Q96QN0; Q9UCK9; Q9UCL0;
DE   RecName: Full=Serum amyloid A-2 protein;
DE            Short=SAA2;
DE   Flags: Precursor;
GN   Name=SAA2;
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
//
ID   SAA4_HUMAN              Reviewed;         130 AA.
AC   P35542; Q6FHJ4;
DE   RecName: Full=Serum amyloid A-4 protein;
DE   AltName: Full=Constitutively expressed serum amyloid A protein;
DE            Short=C-SAA;
DE   Flags: Precursor;
GN   Name=SAA4; Synonyms=CSAA;
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
//
ID   SAAL1_HUMAN             Reviewed;         474 AA.
AC   Q96ER3; A6NH05;
DE   RecName: Full=Protein SAAL1;
GN   Name=SAAL1;
DR   GO; GO:0006953; P:acute-phase response; IEA:InterPro.
//
ID   SAC1_HUMAN              Reviewed;         587 AA.
AC   Q9NTJ5; A8K527; O94935; Q7LA14; Q7LA22; Q96AX7; Q9NQ46; Q9NQ57;
DE   RecName: Full=Phosphatidylinositide phosphatase SAC1;
DE            EC=3.1.3.-;
DE   AltName: Full=Suppressor of actin mutations 1-like protein;
GN   Name=SACM1L; Synonyms=KIAA0851;
DR   GO; GO:0016791; F:phosphatase activity; ISS:UniProtKB.
DR   GO; GO:0034593; F:phosphatidylinositol bisphosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IEA:Ensembl.
DR   GO; GO:0043812; F:phosphatidylinositol-4-phosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:Ensembl.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SAC2_HUMAN              Reviewed;        1132 AA.
AC   Q9Y2H2; B3KRF1; D3DRD1; Q2T9J4; Q5W135; Q5W136; Q6NVY2; Q86U97;
AC   Q9H3D9; Q9NT51;
DE   RecName: Full=Phosphatidylinositide phosphatase SAC2;
DE            EC=3.1.3.-;
DE   AltName: Full=Inositol polyphosphate 5-phosphatase F;
DE   AltName: Full=Sac domain-containing inositol phosphatase 2;
DE   AltName: Full=Sac domain-containing phosphoinositide 5-phosphatase 2;
DE            Short=hSAC2;
GN   Name=INPP5F; Synonyms=KIAA0966, SAC2; ORFNames=MSTP007, MSTP047;
DR   GO; GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IEA:Ensembl.
DR   GO; GO:0031161; P:phosphatidylinositol catabolic process; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:Ensembl.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IEA:Ensembl.
//
ID   SAC31_HUMAN             Reviewed;         404 AA.
AC   A6NKF1; A8MX08; Q99773;
DE   RecName: Full=SAC3 domain-containing protein 1;
DE   AltName: Full=SAC3 homology domain-containing protein 1;
GN   Name=SAC3D1; Synonyms=SHD1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; IEA:Ensembl.
DR   GO; GO:0051225; P:spindle assembly; IEA:Ensembl.
//
ID   SACA1_HUMAN             Reviewed;         294 AA.
AC   Q9HBV2;
DE   RecName: Full=Sperm acrosome membrane-associated protein 1;
DE   AltName: Full=Sperm acrosomal membrane-associated protein 32;
DE   Flags: Precursor;
GN   Name=SPACA1; Synonyms=SAMP32;
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
//
ID   SACA3_HUMAN             Reviewed;         215 AA.
AC   Q8IXA5; Q7Z4Y5;
DE   RecName: Full=Sperm acrosome membrane-associated protein 3;
DE   AltName: Full=Cancer/testis antigen 54;
DE            Short=CT54;
DE   AltName: Full=Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17;
DE   AltName: Full=Lysozyme-like protein 3;
DE   AltName: Full=Sperm lysozyme-like protein 1;
DE   AltName: Full=Sperm protein reactive with antisperm antibodies;
DE            Short=Sperm protein reactive with ASA;
DE   Contains:
DE     RecName: Full=Sperm acrosome membrane-associated protein 3, membrane form;
DE   Contains:
DE     RecName: Full=Sperm acrosome membrane-associated protein 3, processed form;
GN   Name=SPACA3; Synonyms=LYC3, LYZL3, SLLP1, SPRASA;
GN   ORFNames=UNQ424/PRO862;
DR   GO; GO:0003796; F:lysozyme activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016998; P:cell wall macromolecule catabolic process; TAS:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; TAS:UniProtKB.
DR   GO; GO:0042117; P:monocyte activation; TAS:UniProtKB.
DR   GO; GO:0009253; P:peptidoglycan catabolic process; TAS:UniProtKB.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; TAS:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; TAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0035036; P:sperm-egg recognition; IEA:Ensembl.
//
ID   SACA4_HUMAN             Reviewed;         124 AA.
AC   Q8TDM5;
DE   RecName: Full=Sperm acrosome membrane-associated protein 4;
DE   AltName: Full=Sperm acrosomal membrane-associated protein 14;
DE   Flags: Precursor;
GN   Name=SPACA4; Synonyms=SAMP14; ORFNames=UNQ3046/PRO9862;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SACS_HUMAN              Reviewed;        4579 AA.
AC   Q9NZJ4; O94835; Q5T9J5; Q5T9J7; Q5T9J8; Q68DF5; Q6MZR4; Q8NBF9;
DE   RecName: Full=Sacsin;
DE   AltName: Full=DnaJ homolog subfamily C member 29;
DE            Short=DNAJC29;
GN   Name=SACS; Synonyms=KIAA0730;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051087; F:chaperone binding; IDA:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:BHF-UCL.
DR   GO; GO:0070628; F:proteasome binding; IPI:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0090084; P:negative regulation of inclusion body assembly; IMP:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   SAE1_HUMAN              Reviewed;         346 AA.
AC   Q9UBE0; B2RDP5; B3KMQ2; F5GXX7; G3XAK6; O95717; Q9P020;
DE   RecName: Full=SUMO-activating enzyme subunit 1;
DE   AltName: Full=Ubiquitin-like 1-activating enzyme E1A;
DE   Contains:
DE     RecName: Full=SUMO-activating enzyme subunit 1, N-terminally processed;
GN   Name=SAE1; Synonyms=AOS1, SUA1, UBLE1A;
DR   GO; GO:0043008; F:ATP-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IDA:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004839; F:ubiquitin activating enzyme activity; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:UniProtKB.
//
ID   SAE2_HUMAN              Reviewed;         640 AA.
AC   Q9UBT2; O95605; Q59H87; Q6IBP6; Q9NTJ1; Q9UED2;
DE   RecName: Full=SUMO-activating enzyme subunit 2;
DE            EC=6.3.2.-;
DE   AltName: Full=Anthracycline-associated resistance ARX;
DE   AltName: Full=Ubiquitin-like 1-activating enzyme E1B;
DE   AltName: Full=Ubiquitin-like modifier-activating enzyme 2;
GN   Name=UBA2; Synonyms=SAE2, UBLE1B; ORFNames=HRIHFB2115;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0019948; F:SUMO activating enzyme activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
//
ID   SAFB1_HUMAN             Reviewed;         915 AA.
AC   Q15424; A0AV56; B7Z5B6; B7ZLP6; F5H0H3; O60406; Q59HH8;
DE   RecName: Full=Scaffold attachment factor B1;
DE            Short=SAF-B;
DE            Short=SAF-B1;
DE   AltName: Full=HSP27 estrogen response element-TATA box-binding protein;
DE            Short=HSP27 ERE-TATA-binding protein;
GN   Name=SAFB; Synonyms=HAP, HET, SAFB1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:ProtInc.
DR   GO; GO:0040007; P:growth; IEA:Ensembl.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SAFB2_HUMAN             Reviewed;         953 AA.
AC   Q14151; Q8TB13;
DE   RecName: Full=Scaffold attachment factor B2;
DE            Short=SAF-B2;
GN   Name=SAFB2; Synonyms=KIAA0138;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SAGE1_HUMAN             Reviewed;         904 AA.
AC   Q9NXZ1; Q5JNW0;
DE   RecName: Full=Sarcoma antigen 1;
DE   AltName: Full=Cancer/testis antigen 14;
DE            Short=CT14;
GN   Name=SAGE1; Synonyms=SAGE;
//
ID   SAHH2_HUMAN             Reviewed;         530 AA.
AC   O43865; B4E168; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84;
DE   RecName: Full=Putative adenosylhomocysteinase 2;
DE            Short=AdoHcyase 2;
DE            EC=3.3.1.1;
DE   AltName: Full=DC-expressed AHCY-like molecule;
DE   AltName: Full=S-adenosyl-L-homocysteine hydrolase 2;
DE   AltName: Full=S-adenosylhomocysteine hydrolase-like protein 1;
GN   Name=AHCYL1; Synonyms=DCAL, XPVKONA;
DR   GO; GO:0004013; F:adenosylhomocysteinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:Ensembl.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0044070; P:regulation of anion transport; IEA:Ensembl.
DR   GO; GO:0032412; P:regulation of ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0031440; P:regulation of mRNA 3'-end processing; IEA:Ensembl.
//
ID   SAHH3_HUMAN             Reviewed;         611 AA.
AC   Q96HN2; B4DIZ5; D9N155; O94917;
DE   RecName: Full=Putative adenosylhomocysteinase 3;
DE            Short=AdoHcyase 3;
DE            EC=3.3.1.1;
DE   AltName: Full=S-adenosyl-L-homocysteine hydrolase 3;
DE   AltName: Full=S-adenosylhomocysteine hydrolase-like protein 2;
GN   Name=AHCYL2; Synonyms=KIAA0828;
DR   GO; GO:0004013; F:adenosylhomocysteinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
//
ID   SAHH_HUMAN              Reviewed;         432 AA.
AC   P23526; A8K307; B3KUN3; E1P5P2; F5H737; Q96A36;
DE   RecName: Full=Adenosylhomocysteinase;
DE            Short=AdoHcyase;
DE            EC=3.3.1.1;
DE   AltName: Full=S-adenosyl-L-homocysteine hydrolase;
GN   Name=AHCY; Synonyms=SAHH;
DR   GuidetoPHARMACOLOGY; 1233; -.
DR   GO; GO:0004013; F:adenosylhomocysteinase activity; TAS:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   SALL1_HUMAN             Reviewed;        1324 AA.
AC   Q9NSC2; Q99881; Q9NSC3; Q9P1R0;
DE   RecName: Full=Sal-like protein 1;
DE   AltName: Full=Spalt-like transcription factor 1;
DE   AltName: Full=Zinc finger protein 794;
DE   AltName: Full=Zinc finger protein SALL1;
DE   AltName: Full=Zinc finger protein Spalt-1;
DE            Short=HSal1;
DE            Short=Sal-1;
GN   Name=SALL1; Synonyms=SAL1, ZNF794;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEP:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048566; P:embryonic digestive tract development; IMP:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IMP:UniProtKB.
DR   GO; GO:0035136; P:forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0008406; P:gonad development; IEP:UniProtKB.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0016575; P:histone deacetylation; ISS:GOC.
DR   GO; GO:0031129; P:inductive cell-cell signaling; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IMP:UniProtKB.
DR   GO; GO:0072073; P:kidney epithelium development; ISS:UniProtKB.
DR   GO; GO:0060173; P:limb development; IMP:UniProtKB.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEP:UniProtKB.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0021889; P:olfactory bulb interneuron differentiation; ISS:UniProtKB.
DR   GO; GO:0061034; P:olfactory bulb mitral cell layer development; IMP:UniProtKB.
DR   GO; GO:0021553; P:olfactory nerve development; ISS:UniProtKB.
DR   GO; GO:0042473; P:outer ear morphogenesis; IMP:UniProtKB.
DR   GO; GO:0021983; P:pituitary gland development; IEP:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000177; P:regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0072092; P:ureteric bud invasion; ISS:UniProtKB.
DR   GO; GO:0003281; P:ventricular septum development; ISS:UniProtKB.
//
ID   SALL2_HUMAN             Reviewed;        1007 AA.
AC   Q9Y467; B2RMX6; B9EGK8; Q9Y4G1;
DE   RecName: Full=Sal-like protein 2;
DE   AltName: Full=Zinc finger protein 795;
DE   AltName: Full=Zinc finger protein SALL2;
DE   AltName: Full=Zinc finger protein Spalt-2;
DE            Short=Sal-2;
DE            Short=hSal2;
GN   Name=SALL2; Synonyms=KIAA0360, SAL2, ZNF795;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SALL3_HUMAN             Reviewed;        1300 AA.
AC   Q9BXA9; Q9UGH1;
DE   RecName: Full=Sal-like protein 3;
DE   AltName: Full=Zinc finger protein 796;
DE   AltName: Full=Zinc finger protein SALL3;
DE            Short=hSALL3;
GN   Name=SALL3; Synonyms=ZNF796;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035136; P:forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035137; P:hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0021891; P:olfactory bulb interneuron development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SALL4_HUMAN             Reviewed;        1053 AA.
AC   Q9UJQ4; A2A2D8; Q540H3; Q6Y8G6;
DE   RecName: Full=Sal-like protein 4;
DE   AltName: Full=Zinc finger protein 797;
DE   AltName: Full=Zinc finger protein SALL4;
GN   Name=SALL4; Synonyms=ZNF797;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   SAM10_HUMAN             Reviewed;         202 AA.
AC   Q9BYL1;
DE   RecName: Full=Sterile alpha motif domain-containing protein 10;
DE            Short=SAM domain-containing protein 10;
GN   Name=SAMD10; Synonyms=C20orf136;
//
ID   SAM11_HUMAN             Reviewed;         681 AA.
AC   Q96NU1; A2AA76; I7FV78; I7FV81; I7G0Z6; Q5SV96; Q5SV99; Q5SVA0;
AC   Q8N195; Q8TB59;
DE   RecName: Full=Sterile alpha motif domain-containing protein 11;
DE            Short=SAM domain-containing protein 11;
GN   Name=SAMD11;
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   SAM12_HUMAN             Reviewed;         201 AA.
AC   Q8N8I0; Q0P502;
DE   RecName: Full=Sterile alpha motif domain-containing protein 12;
DE            Short=SAM domain-containing protein 12;
GN   Name=SAMD12;
//
ID   SAM13_HUMAN             Reviewed;         122 AA.
AC   Q5VXD3; B3KPW8; D3DT11; Q53AI4; Q5VXD2; Q5VXD4;
DE   RecName: Full=Sterile alpha motif domain-containing protein 13;
DE            Short=SAM domain-containing protein 13;
GN   Name=SAMD13; ORFNames=HSD-42, HSD42;
//
ID   SAM14_HUMAN             Reviewed;         417 AA.
AC   Q8IZD0; A5D8V1; Q8N2X0;
DE   RecName: Full=Sterile alpha motif domain-containing protein 14;
DE            Short=SAM domain-containing protein 14;
GN   Name=SAMD14;
//
ID   SAM15_HUMAN             Reviewed;         674 AA.
AC   Q9P1V8; Q2M3P3;
DE   RecName: Full=Sterile alpha motif domain-containing protein 15;
DE            Short=SAM domain-containing protein 15;
GN   Name=SAMD15; Synonyms=C14orf174, FAM15A;
//
ID   SAM50_HUMAN             Reviewed;         469 AA.
AC   Q9Y512; Q53HC4; Q56VW7; Q969Y9; Q96I46; Q9NW85; Q9UQM9;
DE   RecName: Full=Sorting and assembly machinery component 50 homolog;
DE   AltName: Full=Transformation-related gene 3 protein;
DE            Short=TRG-3;
GN   Name=SAMM50; Synonyms=SAM50; ORFNames=CGI-51, TRG3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0045040; P:protein import into mitochondrial outer membrane; IDA:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   SAM9L_HUMAN             Reviewed;        1584 AA.
AC   Q8IVG5; A0JP23; A0JP24; A0PJG8; A4D1G8; D6W5Q6; Q2TV71; Q2TV75;
AC   Q2UZV8; Q8IWI4; Q8N3L9; Q8N875;
DE   RecName: Full=Sterile alpha motif domain-containing protein 9-like;
DE            Short=SAM domain-containing protein 9-like;
GN   Name=SAMD9L; Synonyms=C7orf6, DRIF2, KIAA2005, UEF;
//
ID   SAMC_HUMAN              Reviewed;         274 AA.
AC   Q70HW3; A8K758; B3KRZ7; Q7Z786; Q96E68;
DE   RecName: Full=S-adenosylmethionine mitochondrial carrier protein;
DE   AltName: Full=Mitochondrial S-adenosylmethionine transporter;
DE   AltName: Full=Solute carrier family 25 member 26;
GN   Name=SLC25A26; Synonyms=SAMC;
DR   GO; GO:0000095; F:S-adenosyl-L-methionine transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:1901962; P:S-adenosyl-L-methionine transmembrane transport; IMP:GOC.
DR   GO; GO:0015805; P:S-adenosyl-L-methionine transport; IMP:UniProtKB.
//
ID   SAMD1_HUMAN             Reviewed;         538 AA.
AC   Q6SPF0; Q6P0R3; Q6PIS7; Q96IM4;
DE   RecName: Full=Atherin;
DE   AltName: Full=Sterile alpha motif domain-containing protein 1;
DE            Short=SAM domain-containing protein 1;
GN   Name=SAMD1;
//
ID   SAMD3_HUMAN             Reviewed;         520 AA.
AC   Q8N6K7; E1P576; Q4VXD8; Q8NAY1; Q8NB96;
DE   RecName: Full=Sterile alpha motif domain-containing protein 3;
DE            Short=SAM domain-containing protein 3;
GN   Name=SAMD3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SAMD7_HUMAN             Reviewed;         446 AA.
AC   Q7Z3H4;
DE   RecName: Full=Sterile alpha motif domain-containing protein 7;
DE            Short=SAM domain-containing protein 7;
GN   Name=SAMD7;
//
ID   SAMD5_HUMAN             Reviewed;         173 AA.
AC   Q5TGI4;
DE   RecName: Full=Sterile alpha motif domain-containing protein 5;
DE            Short=SAM domain-containing protein 5;
GN   Name=SAMD5; Synonyms=SAMDC1;
//
ID   SAMD8_HUMAN             Reviewed;         415 AA.
AC   Q96LT4; Q5JSC5; Q5JSC8; Q66K52;
DE   RecName: Full=Sphingomyelin synthase-related protein 1;
DE            Short=SMSr;
DE            EC=2.7.8.-;
DE   AltName: Full=Ceramide phosphoethanolamine synthase;
DE            Short=CPE synthase;
DE   AltName: Full=Sterile alpha motif domain-containing protein 8;
DE            Short=SAM domain-containing protein 8;
GN   Name=SAMD8;
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:2000303; P:regulation of ceramide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006686; P:sphingomyelin biosynthetic process; NAS:UniProtKB.
//
ID   SAMD9_HUMAN             Reviewed;        1589 AA.
AC   Q5K651; A2RU68; Q5K649; Q6P080; Q75N21; Q8IVG6; Q9NXS8;
DE   RecName: Full=Sterile alpha motif domain-containing protein 9;
DE            Short=SAM domain-containing protein 9;
GN   Name=SAMD9; Synonyms=C7orf5, DRIF1, KIAA2004, OEF1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SAMH1_HUMAN             Reviewed;         626 AA.
AC   Q9Y3Z3; B4E2A5; E1P5V2; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9;
DE   RecName: Full=Deoxynucleoside triphosphate triphosphohydrolase SAMHD1;
DE            Short=dNTPase;
DE            EC=3.1.5.-;
DE   AltName: Full=Dendritic cell-derived IFNG-induced protein;
DE            Short=DCIP;
DE   AltName: Full=Monocyte protein 5;
DE            Short=MOP-5;
DE   AltName: Full=SAM domain and HD domain-containing protein 1;
GN   Name=SAMHD1; Synonyms=MOP5;
DR   GO; GO:0032567; F:dGTP binding; IDA:UniProtKB.
DR   GO; GO:0008832; F:dGTPase activity; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0046061; P:dATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0006203; P:dGTP catabolic process; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; IMP:UniProtKB.
//
ID   SAMN1_HUMAN             Reviewed;         373 AA.
AC   Q9NSI8; B3KWJ3; F8WAA1; Q8NFF7; Q9C041;
DE   RecName: Full=SAM domain-containing protein SAMSN-1;
DE   AltName: Full=Hematopoietic adaptor containing SH3 and SAM domains 1;
DE   AltName: Full=Nash1;
DE   AltName: Full=SAM domain, SH3 domain and nuclear localization signals protein 1;
DE   AltName: Full=SH3-SAM adaptor protein;
GN   Name=SAMSN1; Synonyms=HACS1;
DR   GO; GO:0001784; F:phosphotyrosine binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0002820; P:negative regulation of adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0050869; P:negative regulation of B cell activation; ISS:UniProtKB.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
//
ID   SAMP_HUMAN              Reviewed;         223 AA.
AC   P02743;
DE   RecName: Full=Serum amyloid P-component;
DE            Short=SAP;
DE   AltName: Full=9.5S alpha-1-glycoprotein;
DE   Contains:
DE     RecName: Full=Serum amyloid P-component(1-203);
DE   Flags: Precursor;
GN   Name=APCS; Synonyms=PTX2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006953; P:acute-phase response; TAS:ProtInc.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
//
ID   SAP18_HUMAN             Reviewed;         153 AA.
AC   O00422; B2R494; Q2TTR4; Q6IAW9; Q8N606; Q9UF14;
DE   RecName: Full=Histone deacetylase complex subunit SAP18;
DE   AltName: Full=18 kDa Sin3-associated polypeptide;
DE   AltName: Full=2HOR0202;
DE   AltName: Full=Cell growth-inhibiting gene 38 protein;
DE   AltName: Full=Sin3-associated polypeptide p18;
GN   Name=SAP18; ORFNames=GIG38;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SAP25_HUMAN             Reviewed;         199 AA.
AC   Q8TEE9;
DE   RecName: Full=Histone deacetylase complex subunit SAP25;
DE   AltName: Full=25 kDa Sin3-associated polypeptide;
DE   AltName: Full=Sin3 corepressor complex subunit SAP25;
GN   Name=SAP25;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SAP30_HUMAN             Reviewed;         220 AA.
AC   O75446; D3DP38;
DE   RecName: Full=Histone deacetylase complex subunit SAP30;
DE   AltName: Full=30 kDa Sin3-associated polypeptide;
DE   AltName: Full=Sin3 corepressor complex subunit SAP30;
DE   AltName: Full=Sin3-associated polypeptide p30;
GN   Name=SAP30;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SAP3_HUMAN              Reviewed;         193 AA.
AC   P17900; B2R699; D3DQH6; Q14426; Q14428; Q6LBL5;
DE   RecName: Full=Ganglioside GM2 activator;
DE   AltName: Full=Cerebroside sulfate activator protein;
DE   AltName: Full=GM2-AP;
DE   AltName: Full=Sphingolipid activator protein 3;
DE            Short=SAP-3;
DE   Contains:
DE     RecName: Full=Ganglioside GM2 activator isoform short;
DE   Flags: Precursor;
GN   Name=GM2A;
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:Ensembl.
DR   GO; GO:0005319; F:lipid transporter activity; IEA:Ensembl.
DR   GO; GO:0016004; F:phospholipase activator activity; IEA:Ensembl.
DR   GO; GO:0006689; P:ganglioside catabolic process; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; IEA:Ensembl.
DR   GO; GO:0051345; P:positive regulation of hydrolase activity; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   SAPC1_HUMAN             Reviewed;         148 AA.
AC   Q5SSQ6; A2ABF2; A2ABS9; Q9Y335;
DE   RecName: Full=Suppressor APC domain-containing protein 1;
DE   AltName: Full=Protein G7d;
GN   Name=SAPCD1; Synonyms=C6orf26, G7D, NG23;
//
ID   SAPC2_HUMAN             Reviewed;         394 AA.
AC   Q86UD0;
DE   RecName: Full=Suppressor APC domain-containing protein 2;
DE   AltName: Full=Tumor specificity and mitosis phase-dependent expression protein;
DE            Short=TS/MDEP;
DE   AltName: Full=p42.3;
GN   Name=SAPCD2; Synonyms=C9orf140;
//
ID   SAPL1_HUMAN             Reviewed;         521 AA.
AC   Q6NUJ1; A0A184; Q8N7T4;
DE   RecName: Full=Proactivator polypeptide-like 1;
DE   Contains:
DE     RecName: Full=Saposin A-like;
DE   Contains:
DE     RecName: Full=Saposin B-Val-like;
DE   Contains:
DE     RecName: Full=Saposin B-like;
DE   Contains:
DE     RecName: Full=Saposin C-like;
DE   Contains:
DE     RecName: Full=Saposin D-like;
DE   Flags: Precursor;
GN   Name=PSAPL1;
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:UniProtKB-KW.
//
ID   SAP_HUMAN               Reviewed;         524 AA.
AC   P07602; P07292; P15793; P78538; P78541; P78546; P78547; P78558;
AC   Q53Y86; Q6IBQ6; Q92739; Q92740; Q92741; Q92742;
DE   RecName: Full=Prosaposin;
DE   AltName: Full=Proactivator polypeptide;
DE   Contains:
DE     RecName: Full=Saposin-A;
DE     AltName: Full=Protein A;
DE   Contains:
DE     RecName: Full=Saposin-B-Val;
DE   Contains:
DE     RecName: Full=Saposin-B;
DE     AltName: Full=Cerebroside sulfate activator;
DE              Short=CSAct;
DE     AltName: Full=Dispersin;
DE     AltName: Full=Sphingolipid activator protein 1;
DE              Short=SAP-1;
DE     AltName: Full=Sulfatide/GM1 activator;
DE   Contains:
DE     RecName: Full=Saposin-C;
DE     AltName: Full=A1 activator;
DE     AltName: Full=Co-beta-glucosidase;
DE     AltName: Full=Glucosylceramidase activator;
DE     AltName: Full=Sphingolipid activator protein 2;
DE              Short=SAP-2;
DE   Contains:
DE     RecName: Full=Saposin-D;
DE     AltName: Full=Component C;
DE     AltName: Full=Protein C;
DE   Flags: Precursor;
GN   Name=PSAP; Synonyms=GLBA, SAP1;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0060742; P:epithelial cell differentiation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006869; P:lipid transport; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0060736; P:prostate gland growth; IEA:Ensembl.
DR   GO; GO:0019216; P:regulation of lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   SAR1A_HUMAN             Reviewed;         198 AA.
AC   Q9NR31;
DE   RecName: Full=GTP-binding protein SAR1a;
DE   AltName: Full=COPII-associated small GTPase;
GN   Name=SAR1A; Synonyms=SAR1, SARA, SARA1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   SAR1B_HUMAN             Reviewed;         198 AA.
AC   Q9Y6B6; D3DQA4; Q567T4;
DE   RecName: Full=GTP-binding protein SAR1b;
DE   AltName: Full=GTP-binding protein B;
DE            Short=GTBPB;
GN   Name=SAR1B; Synonyms=SARA2, SARB;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SARAF_HUMAN             Reviewed;         339 AA.
AC   Q96BY9; B3KQQ4; B7Z9J1; D3DSU7; H9MHJ8; H9MHJ9; Q53HE8; Q9UNZ3;
AC   Q9Y683;
DE   RecName: Full=Store-operated calcium entry-associated regulatory factor;
DE            Short=SARAF;
DE            Short=SOCE-associated regulatory factor;
DE   AltName: Full=HBV X-transactivated gene 3 protein;
DE   AltName: Full=HBV XAg-transactivated protein 3;
DE   AltName: Full=Protein FOAP-7;
DE   AltName: Full=Transmembrane protein 66;
DE   Flags: Precursor;
GN   Name=TMEM66; Synonyms=SARAF, XTP3;
GN   ORFNames=HSPC035, NPD003, PSEC0019, UNQ1967/PRO4499;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; IDA:UniProtKB.
//
ID   SARCO_HUMAN             Reviewed;          31 AA.
AC   O00631; Q6ICV3;
DE   RecName: Full=Sarcolipin;
GN   Name=SLN;
DR   GO; GO:0051117; F:ATPase binding; ISS:BHF-UCL.
DR   GO; GO:0004857; F:enzyme inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:1901877; P:negative regulation of calcium ion binding; ISS:BHF-UCL.
DR   GO; GO:0090281; P:negative regulation of calcium ion import; ISS:BHF-UCL.
DR   GO; GO:1901020; P:negative regulation of calcium ion transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; ISS:BHF-UCL.
DR   GO; GO:0043242; P:negative regulation of protein complex disassembly; ISS:BHF-UCL.
DR   GO; GO:1901881; P:positive regulation of protein depolymerization; ISS:BHF-UCL.
DR   GO; GO:0051924; P:regulation of calcium ion transport; ISS:UniProtKB.
DR   GO; GO:1901894; P:regulation of calcium-transporting ATPase activity; IDA:UniProtKB.
DR   GO; GO:1901077; P:regulation of relaxation of muscle; ISS:UniProtKB.
DR   GO; GO:0070296; P:sarcoplasmic reticulum calcium ion transport; ISS:UniProtKB.
//
ID   SARDH_HUMAN             Reviewed;         918 AA.
AC   Q9UL12; B2RMR5; B7ZLT6; Q5SYV0; Q9Y280; Q9Y2Y3;
DE   RecName: Full=Sarcosine dehydrogenase, mitochondrial;
DE            Short=SarDH;
DE            EC=1.5.8.3;
DE   AltName: Full=BPR-2;
DE   Flags: Precursor;
GN   Name=SARDH; Synonyms=DMGDHL1;
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:InterPro.
DR   GO; GO:0008480; F:sarcosine dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006546; P:glycine catabolic process; IEA:InterPro.
//
ID   SARG_HUMAN              Reviewed;         601 AA.
AC   Q9BW04; C9JV41; Q658X3;
DE   RecName: Full=Specifically androgen-regulated gene protein;
GN   Name=SARG; Synonyms=C1orf116;
//
ID   SARM1_HUMAN             Reviewed;         724 AA.
AC   Q6SZW1; O60277; Q7LGG3; Q9NXY5;
DE   RecName: Full=Sterile alpha and TIR motif-containing protein 1;
DE   AltName: Full=Sterile alpha and Armadillo repeat protein;
DE   AltName: Full=Sterile alpha motif domain-containing protein 2;
DE            Short=MyD88-5;
DE            Short=SAM domain-containing protein 2;
DE   AltName: Full=Tir-1 homolog;
DE   Flags: Precursor;
GN   Name=SARM1; Synonyms=KIAA0524, SAMD2, SARM;
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:1901214; P:regulation of neuron death; ISS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   SARNP_HUMAN             Reviewed;         210 AA.
AC   P82979; A8K393; Q9P066;
DE   RecName: Full=SAP domain-containing ribonucleoprotein;
DE   AltName: Full=Cytokine-induced protein of 29 kDa;
DE   AltName: Full=Nuclear protein Hcc-1;
DE   AltName: Full=Proliferation-associated cytokine-inducible protein CIP29;
GN   Name=SARNP; Synonyms=HCC1; ORFNames=HSPC316;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SART3_HUMAN             Reviewed;         963 AA.
AC   Q15020; A8K2E4; Q2M2H0; Q58F06; Q8IUS1; Q96J95;
DE   RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3;
DE            Short=SART-3;
DE            Short=hSART-3;
DE   AltName: Full=Tat-interacting protein of 110 kDa;
DE            Short=Tip110;
GN   Name=SART3; Synonyms=KIAA0156, TIP110;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IDA:MGI.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   SAS10_HUMAN             Reviewed;         479 AA.
AC   Q9NQZ2; Q6FI82;
DE   RecName: Full=Something about silencing protein 10;
DE   AltName: Full=Charged amino acid-rich leucine zipper 1;
DE            Short=CRL1;
DE   AltName: Full=Disrupter of silencing SAS10;
DE   AltName: Full=UTP3 homolog;
GN   Name=UTP3; Synonyms=CRLZ1, SAS10;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; ISS:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
//
ID   SAS6_HUMAN              Reviewed;         657 AA.
AC   Q6UVJ0; D3DT55; Q8N3K0;
DE   RecName: Full=Spindle assembly abnormal protein 6 homolog;
DE            Short=HsSAS-6;
GN   Name=SASS6; Synonyms=SAS6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007099; P:centriole replication; IMP:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
//
ID   SASH1_HUMAN             Reviewed;        1247 AA.
AC   O94885; Q5TGN5; Q8TAI0; Q9H7R7;
DE   RecName: Full=SAM and SH3 domain-containing protein 1;
DE   AltName: Full=Proline-glutamate repeat-containing protein;
GN   Name=SASH1; Synonyms=KIAA0790, PEPE1;
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IDA:MGI.
DR   GO; GO:0008022; F:protein C-terminus binding; IDA:MGI.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:MGI.
DR   GO; GO:0019901; F:protein kinase binding; IDA:MGI.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:MGI.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:MGI.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:MGI.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:MGI.
DR   GO; GO:1901224; P:positive regulation of NIK/NF-kappaB signaling; IMP:MGI.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IMP:MGI.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:MGI.
DR   GO; GO:1902498; P:regulation of protein autoubiquitination; IDA:MGI.
DR   GO; GO:1900044; P:regulation of protein K63-linked ubiquitination; IDA:MGI.
//
ID   SAST_HUMAN              Reviewed;         265 AA.
AC   Q9NV23; Q5VUB6; Q9NUW1;
DE   RecName: Full=S-acyl fatty acid synthase thioesterase, medium chain;
DE            EC=3.1.2.14;
DE   AltName: Full=Augmented in rheumatoid arthritis 1;
DE            Short=AURA1;
DE   AltName: Full=Oleoyl-ACP hydrolase;
DE   AltName: Full=Thioesterase II;
DE   AltName: Full=Thioesterase domain-containing protein 1;
GN   Name=OLAH; Synonyms=THEDC1;
DR   GO; GO:0016295; F:myristoyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
//
ID   SASH3_HUMAN             Reviewed;         380 AA.
AC   O75995; A6NCH1; A8K7K8; Q5JZ38;
DE   RecName: Full=SAM and SH3 domain-containing protein 3;
DE   AltName: Full=SH3 protein expressed in lymphocytes homolog;
GN   Name=SASH3; Synonyms=CXorf9, SLY;
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0002639; P:positive regulation of immunoglobulin production; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
//
ID   SAT1_HUMAN              Reviewed;         171 AA.
AC   P21673;
DE   RecName: Full=Diamine acetyltransferase 1;
DE            EC=2.3.1.57;
DE   AltName: Full=Polyamine N-acetyltransferase 1;
DE   AltName: Full=Putrescine acetyltransferase;
DE   AltName: Full=Spermidine/spermine N(1)-acetyltransferase 1;
DE            Short=SSAT;
DE            Short=SSAT-1;
GN   Name=SAT1; Synonyms=SAT;
DR   GO; GO:0004145; F:diamine N-acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019809; F:spermidine binding; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006596; P:polyamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0009447; P:putrescine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0032918; P:spermidine acetylation; IEA:Ensembl.
//
ID   SAT2_HUMAN              Reviewed;         170 AA.
AC   Q96F10;
DE   RecName: Full=Diamine acetyltransferase 2;
DE            EC=2.3.1.57;
DE   AltName: Full=Polyamine N-acetyltransferase 2;
DE   AltName: Full=Spermidine/spermine N(1)-acetyltransferase 2;
DE   AltName: Full=Thialysine N-epsilon-acetyltransferase;
GN   Name=SAT2; Synonyms=SSAT2;
DR   GO; GO:0004145; F:diamine N-acetyltransferase activity; IDA:UniProt.
DR   GO; GO:0046204; P:nor-spermidine metabolic process; IDA:UniProt.
DR   GO; GO:0032920; P:putrescine acetylation; IDA:UniProt.
DR   GO; GO:0009447; P:putrescine catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032918; P:spermidine acetylation; IDA:UniProt.
DR   GO; GO:0032919; P:spermine acetylation; IDA:UniProt.
//
ID   SATB1_HUMAN             Reviewed;         763 AA.
AC   Q01826; B3KXF1; C9JTR6; Q59EQ0;
DE   RecName: Full=DNA-binding protein SATB1;
DE   AltName: Full=Special AT-rich sequence-binding protein 1;
GN   Name=SATB1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0050798; P:activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0043367; P:CD4-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043374; P:CD8-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006325; P:chromatin organization; TAS:ProtInc.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; IEA:Ensembl.
DR   GO; GO:0016571; P:histone methylation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.
DR   GO; GO:0060004; P:reflex; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SATB2_HUMAN             Reviewed;         733 AA.
AC   Q9UPW6; A8K5Z8; Q3ZB87; Q4V763;
DE   RecName: Full=DNA-binding protein SATB2;
DE   AltName: Full=Special AT-rich sequence-binding protein 2;
GN   Name=SATB2; Synonyms=KIAA1034;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SATL1_HUMAN             Reviewed;         508 AA.
AC   Q86VE3; A0AVK7; Q5H8V9;
DE   RecName: Full=Spermidine/spermine N(1)-acetyltransferase-like protein 1;
DE            EC=2.3.1.-;
GN   Name=SATL1;
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
//
ID   SATT_HUMAN              Reviewed;         532 AA.
AC   P43007; B7Z3C0; D6W5F0;
DE   RecName: Full=Neutral amino acid transporter A;
DE   AltName: Full=Alanine/serine/cysteine/threonine transporter 1;
DE            Short=ASCT-1;
DE   AltName: Full=SATT;
DE   AltName: Full=Solute carrier family 1 member 4;
GN   Name=SLC1A4; Synonyms=ASCT1, SATT;
DR   GO; GO:0005254; F:chloride channel activity; IDA:UniProtKB.
DR   GO; GO:0015180; F:L-alanine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015184; F:L-cystine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015186; F:L-glutamine transmembrane transporter activity; TAS:BHF-UCL.
DR   GO; GO:0034590; F:L-hydroxyproline transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015193; F:L-proline transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015194; F:L-serine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015195; F:L-threonine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0017153; F:sodium:dicarboxylate symporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:GOC.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0006868; P:glutamine transport; TAS:BHF-UCL.
DR   GO; GO:0034589; P:hydroxyproline transport; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015808; P:L-alanine transport; IDA:UniProtKB.
DR   GO; GO:0015811; P:L-cystine transport; IDA:UniProtKB.
DR   GO; GO:0015825; P:L-serine transport; IDA:UniProtKB.
DR   GO; GO:0035524; P:proline transmembrane transport; IDA:GOC.
DR   GO; GO:0015824; P:proline transport; IDA:UniProtKB.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; NAS:UniProtKB.
DR   GO; GO:0015826; P:threonine transport; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SAV1_HUMAN              Reviewed;         383 AA.
AC   Q9H4B6; A8K4B8; D3DSB6; Q6IA58; Q9H949; Q9HAK9;
DE   RecName: Full=Protein salvador homolog 1;
DE   AltName: Full=45 kDa WW domain protein;
DE            Short=hWW45;
GN   Name=SAV1; Synonyms=WW45;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; ISS:UniProtKB.
DR   GO; GO:0060575; P:intestinal epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0060487; P:lung epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
//
ID   SBDS_HUMAN              Reviewed;         250 AA.
AC   Q9Y3A5; A8K0P4; Q96FX0; Q9NV53;
DE   RecName: Full=Ribosome maturation protein SBDS;
DE   AltName: Full=Shwachman-Bodian-Diamond syndrome protein;
GN   Name=SBDS; ORFNames=CGI-97;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0019843; F:rRNA binding; IDA:UniProtKB.
DR   GO; GO:0048539; P:bone marrow development; IMP:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0030595; P:leukocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0042256; P:mature ribosome assembly; IDA:UniProtKB.
DR   GO; GO:0043148; P:mitotic spindle stabilization; IDA:UniProtKB.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:RefGenome.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
//
ID   SBK1_HUMAN              Reviewed;         424 AA.
AC   Q52WX2;
DE   RecName: Full=Serine/threonine-protein kinase SBK1;
DE            EC=2.7.11.1;
DE   AltName: Full=SH3-binding kinase 1;
GN   Name=SBK1;
DR   GuidetoPHARMACOLOGY; 2193; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   SBK2_HUMAN              Reviewed;         348 AA.
AC   P0C263;
DE   RecName: Full=Serine/threonine-protein kinase SBK2;
DE            EC=2.7.11.1;
DE   AltName: Full=SH3-binding domain kinase family member 2;
DE   AltName: Full=Sugen kinase 69;
DE            Short=SgK069;
GN   Name=SBK2; Synonyms=SGK069;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   SBK3_HUMAN              Reviewed;         359 AA.
AC   P0C264;
DE   RecName: Full=Uncharacterized serine/threonine-protein kinase SBK3;
DE            EC=2.7.11.1;
DE   AltName: Full=SH3-binding domain kinase family member 3;
DE   AltName: Full=Sugen kinase 110;
GN   Name=SBK3; Synonyms=SGK110;
DR   GuidetoPHARMACOLOGY; 2290; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   SBNO1_HUMAN             Reviewed;        1393 AA.
AC   A3KN83; Q05C06; Q3ZTS3; Q9H3T8; Q9NVB2;
DE   RecName: Full=Protein strawberry notch homolog 1;
DE   AltName: Full=Monocyte protein 3;
DE            Short=MOP-3;
GN   Name=SBNO1; Synonyms=MOP3;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   SBNO2_HUMAN             Reviewed;        1366 AA.
AC   Q9Y2G9; A8K8P2; B3KWJ1; O75257; Q3KQX0; Q8TEM0;
DE   RecName: Full=Protein strawberry notch homolog 2;
GN   Name=SBNO2; Synonyms=KIAA0963;
DR   GO; GO:0002281; P:macrophage activation involved in immune response; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SBP1_HUMAN              Reviewed;         472 AA.
AC   Q13228; A6NML9; B2RDR3; B4DKP6; B4E1F3; Q49AQ8; Q96GX7;
DE   RecName: Full=Selenium-binding protein 1;
DE   AltName: Full=56 kDa selenium-binding protein;
DE            Short=SBP56;
DE            Short=SP56;
GN   Name=SELENBP1; Synonyms=SBP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008430; F:selenium binding; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SBP2L_HUMAN             Reviewed;        1101 AA.
AC   Q93073; Q8N767;
DE   RecName: Full=Selenocysteine insertion sequence-binding protein 2-like;
DE            Short=SECIS-binding protein 2-like;
GN   Name=SECISBP2L; Synonyms=KIAA0256;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   SBSN_HUMAN              Reviewed;         590 AA.
AC   Q6UWP8; A8K5J0; E9PBV3;
DE   RecName: Full=Suprabasin;
DE   Flags: Precursor;
GN   Name=SBSN; ORFNames=UNQ698/PRO1343;
//
ID   SBSPO_HUMAN             Reviewed;         264 AA.
AC   Q8IVN8; A8KAA5; Q96J64;
DE   RecName: Full=Somatomedin-B and thrombospondin type-1 domain-containing protein;
DE   AltName: Full=RPE-spondin;
DE   Flags: Precursor;
GN   Name=SBSPON; Synonyms=C8orf84, RPESP;
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   SC11A_HUMAN             Reviewed;         179 AA.
AC   P67812; B2RAD7; O75957; P21378; Q53FQ8;
DE   RecName: Full=Signal peptidase complex catalytic subunit SEC11A;
DE            EC=3.4.21.89;
DE   AltName: Full=Endopeptidase SP18;
DE   AltName: Full=Microsomal signal peptidase 18 kDa subunit;
DE            Short=SPase 18 kDa subunit;
DE   AltName: Full=SEC11 homolog A;
DE   AltName: Full=SEC11-like protein 1;
DE   AltName: Full=SPC18;
GN   Name=SEC11A; Synonyms=SEC11L1, SPC18, SPCS4A;
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SC11C_HUMAN             Reviewed;         192 AA.
AC   Q9BY50; B2RAA3;
DE   RecName: Full=Signal peptidase complex catalytic subunit SEC11C;
DE            EC=3.4.21.89;
DE   AltName: Full=Microsomal signal peptidase 21 kDa subunit;
DE            Short=SPase 21 kDa subunit;
DE   AltName: Full=SEC11 homolog C;
DE   AltName: Full=SEC11-like protein 3;
DE   AltName: Full=SPC21;
GN   Name=SEC11C; Synonyms=SEC11L3, SPC21, SPCS4C;
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SC11B_HUMAN             Reviewed;         166 AA.
AC   P0C7V7;
DE   RecName: Full=Putative signal peptidase complex catalytic subunit SEC11B;
DE            EC=3.4.21.89;
DE   AltName: Full=SEC11 homolog B;
DE   AltName: Full=SEC11-like protein 2;
GN   Name=SEC11B; Synonyms=SEC11L2, SPCS4B;
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
//
ID   SC16A_HUMAN             Reviewed;        2179 AA.
AC   O15027; A1YCA4; Q4G0D7; Q5SXP0; Q5SXP1; Q8N347; Q96HP1;
DE   RecName: Full=Protein transport protein Sec16A;
DE   AltName: Full=SEC16 homolog A;
GN   Name=SEC16A; Synonyms=KIAA0310, SEC16, SEC16L;
DR   GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   SC16B_HUMAN             Reviewed;        1060 AA.
AC   Q96JE7; A3EYF1; Q5HYF6; Q8N7D6; Q96GX6;
DE   RecName: Full=Protein transport protein Sec16B;
DE   AltName: Full=Leucine zipper transcription regulator 2;
DE   AltName: Full=Regucalcin gene promoter region-related protein p117;
DE            Short=RGPR-p117;
DE   AltName: Full=SEC16 homolog B;
GN   Name=SEC16B; Synonyms=KIAA1928, LZTR2, RGPR, SEC16S;
DR   GO; GO:0048208; P:COPII vesicle coating; IEA:InterPro.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IDA:UniProtKB.
DR   GO; GO:0016559; P:peroxisome fission; IMP:UniProtKB.
DR   GO; GO:0007031; P:peroxisome organization; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0070863; P:positive regulation of protein exit from endoplasmic reticulum; IMP:UniProtKB.
DR   GO; GO:0070972; P:protein localization to endoplasmic reticulum; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SC22A_HUMAN             Reviewed;         307 AA.
AC   Q96IW7; B2RE26; Q9Y682;
DE   RecName: Full=Vesicle-trafficking protein SEC22a;
DE   AltName: Full=SEC22 vesicle-trafficking protein homolog A;
DE   AltName: Full=SEC22 vesicle-trafficking protein-like 2;
GN   Name=SEC22A; Synonyms=SEC22L2;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IBA:RefGenome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:RefGenome.
//
ID   SC22B_HUMAN             Reviewed;         215 AA.
AC   O75396; A8K1G0;
DE   RecName: Full=Vesicle-trafficking protein SEC22b;
DE   AltName: Full=ER-Golgi SNARE of 24 kDa;
DE            Short=ERS-24;
DE            Short=ERS24;
DE   AltName: Full=SEC22 vesicle-trafficking protein homolog B;
DE   AltName: Full=SEC22 vesicle-trafficking protein-like 1;
GN   Name=SEC22B; Synonyms=SEC22L1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SC22C_HUMAN             Reviewed;         303 AA.
AC   Q9BRL7; O95152; Q68CX3; Q6UW18;
DE   RecName: Full=Vesicle-trafficking protein SEC22c;
DE   AltName: Full=SEC22 vesicle-trafficking protein homolog C;
DE   AltName: Full=SEC22 vesicle-trafficking protein-like 3;
GN   Name=SEC22C; Synonyms=SEC22L3; ORFNames=UNQ459/PRO784;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:RefGenome.
//
ID   SC23A_HUMAN             Reviewed;         765 AA.
AC   Q15436; B2R5P4; Q8NE16;
DE   RecName: Full=Protein transport protein Sec23A;
DE   AltName: Full=SEC23-related protein A;
GN   Name=SEC23A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   SC23B_HUMAN             Reviewed;         767 AA.
AC   Q15437; D3DW33; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7;
DE   RecName: Full=Protein transport protein Sec23B;
DE   AltName: Full=SEC23-related protein B;
GN   Name=SEC23B;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   SC24A_HUMAN             Reviewed;        1093 AA.
AC   O95486; A8MVW3; Q8WUV2; Q96GP7;
DE   RecName: Full=Protein transport protein Sec24A;
DE   AltName: Full=SEC24-related protein A;
GN   Name=SEC24A;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SC24B_HUMAN             Reviewed;        1268 AA.
AC   O95487; B7ZKM8; B7ZKN4; Q0VG08;
DE   RecName: Full=Protein transport protein Sec24B;
DE   AltName: Full=SEC24-related protein B;
GN   Name=SEC24B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   SC24C_HUMAN             Reviewed;        1094 AA.
AC   P53992; Q8WV25;
DE   RecName: Full=Protein transport protein Sec24C;
DE   AltName: Full=SEC24-related protein C;
GN   Name=SEC24C; Synonyms=KIAA0079;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SC24D_HUMAN             Reviewed;        1032 AA.
AC   O94855; Q8IYI7;
DE   RecName: Full=Protein transport protein Sec24D;
DE   AltName: Full=SEC24-related protein D;
GN   Name=SEC24D; Synonyms=KIAA0755;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SC2B2_HUMAN             Reviewed;          96 AA.
AC   Q4G0G5;
DE   RecName: Full=Secretoglobin family 2B member 2;
DE   AltName: Full=Secretoglobin-like protein;
DE   Flags: Precursor;
GN   Name=SCGB2B2; Synonyms=SCGB4A2, SCGBL;
//
ID   SC31A_HUMAN             Reviewed;        1220 AA.
AC   O94979; B4DIW6; B7ZKZ7; B7ZL00; H7C2W3; Q17RR5; Q5H9P6; Q5XG74;
AC   Q659G7; Q6ZU90; Q7LCX9; Q86TJ0; Q8IZH4; Q9P048; Q9P0A6; Q9UM05;
AC   Q9UM06;
DE   RecName: Full=Protein transport protein Sec31A;
DE   AltName: Full=ABP125;
DE   AltName: Full=ABP130;
DE   AltName: Full=SEC31-like protein 1;
DE   AltName: Full=SEC31-related protein A;
DE   AltName: Full=Web1-like protein;
GN   Name=SEC31A; Synonyms=KIAA0905, SEC31L1; ORFNames=HSPC275, HSPC334;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
//
ID   SC31B_HUMAN             Reviewed;        1179 AA.
AC   Q9NQW1; B7ZM75; Q6MZS3; Q86UF0; Q9Y4Q8;
DE   RecName: Full=Protein transport protein Sec31B;
DE   AltName: Full=SEC31-like protein 2;
DE   AltName: Full=SEC31-related protein B;
DE   AltName: Full=SEC31B-1;
GN   Name=SEC31B; Synonyms=SEC31L2;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   SC5A1_HUMAN             Reviewed;         664 AA.
AC   P13866; B2R7E2; B7Z4Q9; B7ZA69;
DE   RecName: Full=Sodium/glucose cotransporter 1;
DE            Short=Na(+)/glucose cotransporter 1;
DE   AltName: Full=High affinity sodium-glucose cotransporter;
DE   AltName: Full=Solute carrier family 5 member 1;
GN   Name=SLC5A1; Synonyms=NAGT, SGLT1;
DR   GuidetoPHARMACOLOGY; 915; -.
DR   GO; GO:0005412; F:glucose:sodium symporter activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; IMP:MGI.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SC5A2_HUMAN             Reviewed;         672 AA.
AC   P31639;
DE   RecName: Full=Sodium/glucose cotransporter 2;
DE            Short=Na(+)/glucose cotransporter 2;
DE   AltName: Full=Low affinity sodium-glucose cotransporter;
DE   AltName: Full=Solute carrier family 5 member 2;
GN   Name=SLC5A2; Synonyms=SGLT2;
DR   GuidetoPHARMACOLOGY; 916; -.
DR   GO; GO:0005362; F:low-affinity glucose:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0015758; P:glucose transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC5A3_HUMAN             Reviewed;         718 AA.
AC   P53794; O43489;
DE   RecName: Full=Sodium/myo-inositol cotransporter;
DE            Short=Na(+)/myo-inositol cotransporter;
DE   AltName: Full=Sodium/myo-inositol transporter 1;
DE            Short=SMIT1;
DE   AltName: Full=Solute carrier family 5 member 3;
GN   Name=SLC5A3;
DR   GuidetoPHARMACOLOGY; 924; -.
DR   GO; GO:0005367; F:myo-inositol:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0015798; P:myo-inositol transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC5A4_HUMAN             Reviewed;         659 AA.
AC   Q9NY91; O15279;
DE   RecName: Full=Low affinity sodium-glucose cotransporter;
DE   AltName: Full=Sodium/glucose cotransporter 3;
DE            Short=Na(+)/glucose cotransporter 3;
DE   AltName: Full=Solute carrier family 5 member 4;
GN   Name=SLC5A4; Synonyms=SAAT1, SGLT2;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   SC5A5_HUMAN             Reviewed;         643 AA.
AC   Q92911; O43702; Q2M335; Q9NYB6;
DE   RecName: Full=Sodium/iodide cotransporter;
DE            Short=Na(+)/I(-) cotransporter;
DE   AltName: Full=Sodium-iodide symporter;
DE            Short=Na(+)/I(-) symporter;
DE   AltName: Full=Solute carrier family 5 member 5;
GN   Name=SLC5A5; Synonyms=NIS;
DR   GO; GO:0015111; F:iodide transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0008507; F:sodium:iodide symporter activity; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IEP:UniProtKB.
DR   GO; GO:0015705; P:iodide transport; IMP:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006590; P:thyroid hormone generation; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC5A6_HUMAN             Reviewed;         635 AA.
AC   Q9Y289; B2RB85; D6W549; Q969Y5;
DE   RecName: Full=Sodium-dependent multivitamin transporter;
DE            Short=Na(+)-dependent multivitamin transporter;
DE   AltName: Full=Solute carrier family 5 member 6;
GN   Name=SLC5A6; Synonyms=SMVT;
DR   GO; GO:0008523; F:sodium-dependent multivitamin transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0006768; P:biotin metabolic process; TAS:Reactome.
DR   GO; GO:0015878; P:biotin transport; IEA:Ensembl.
DR   GO; GO:0015939; P:pantothenate metabolic process; TAS:Reactome.
DR   GO; GO:0015887; P:pantothenate transmembrane transport; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   SC5A7_HUMAN             Reviewed;         580 AA.
AC   Q9GZV3; Q53TF2;
DE   RecName: Full=High affinity choline transporter 1;
DE   AltName: Full=Hemicholinium-3-sensitive choline transporter;
DE            Short=CHT;
DE   AltName: Full=Solute carrier family 5 member 7;
GN   Name=SLC5A7; Synonyms=CHT1;
DR   GuidetoPHARMACOLOGY; 914; -.
DR   GO; GO:0033265; F:choline binding; IEA:Ensembl.
DR   GO; GO:0015220; F:choline transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0005307; F:choline:sodium symporter activity; IMP:MGI.
DR   GO; GO:0008292; P:acetylcholine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0007271; P:synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SC5A8_HUMAN             Reviewed;         610 AA.
AC   Q8N695; Q2TB99; Q7Z2H9;
DE   RecName: Full=Sodium-coupled monocarboxylate transporter 1;
DE   AltName: Full=Apical iodide transporter;
DE   AltName: Full=Electrogenic sodium monocarboxylate cotransporter;
DE   AltName: Full=Sodium iodide-related cotransporter;
DE   AltName: Full=Solute carrier family 5 member 8;
GN   Name=SLC5A8; Synonyms=AIT, SMCT, SMCT1;
DR   GuidetoPHARMACOLOGY; 922; -.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SC5A9_HUMAN             Reviewed;         681 AA.
AC   Q2M3M2; B3KY87; B7ZL47; E9PAK4; Q5TET3;
DE   RecName: Full=Sodium/glucose cotransporter 4;
DE            Short=Na(+)/glucose cotransporter 4;
DE            Short=hSGLT4;
DE   AltName: Full=Solute carrier family 5 member 9;
GN   Name=SLC5A9; Synonyms=SGLT4;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SC5AA_HUMAN             Reviewed;         596 AA.
AC   A0PJK1; A8MUC9; B4DPI0; B7WPR4; Q6P5X0; Q8IXM4; Q96LQ1;
DE   RecName: Full=Sodium/glucose cotransporter 5;
DE            Short=Na(+)/glucose cotransporter 5;
DE   AltName: Full=Solute carrier family 5 member 10;
GN   Name=SLC5A10; Synonyms=SGLT5;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SC5AB_HUMAN             Reviewed;         675 AA.
AC   Q8WWX8; B7Z329; Q05BF1; Q6PF02; Q6ZUW3; Q86Y55; Q96PP5;
DE   RecName: Full=Sodium/myo-inositol cotransporter 2;
DE            Short=Na(+)/myo-inositol cotransporter 2;
DE   AltName: Full=Sodium-dependent glucose cotransporter;
DE   AltName: Full=Sodium/glucose cotransporter KST1;
DE   AltName: Full=Sodium/myo-inositol transporter 2;
DE            Short=SMIT2;
DE   AltName: Full=Solute carrier family 5 member 11;
GN   Name=SLC5A11; Synonyms=KST1, SLGTX, SMIT2;
DR   GuidetoPHARMACOLOGY; 925; -.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SC5AC_HUMAN             Reviewed;         618 AA.
AC   Q1EHB4; Q86UC7;
DE   RecName: Full=Sodium-coupled monocarboxylate transporter 2;
DE   AltName: Full=Electroneutral sodium monocarboxylate cotransporter;
DE   AltName: Full=Low-affinity sodium-lactate cotransporter;
DE   AltName: Full=Solute carrier family 5 member 12;
GN   Name=SLC5A12; Synonyms=SMCT2;
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   SC5D_HUMAN              Reviewed;         299 AA.
AC   O75845; O00119; Q6GTM5; Q9UK15;
DE   RecName: Full=Lathosterol oxidase;
DE            EC=1.14.21.6;
DE   AltName: Full=C-5 sterol desaturase;
DE   AltName: Full=Delta(7)-sterol 5-desaturase;
DE   AltName: Full=Lathosterol 5-desaturase;
DE   AltName: Full=Sterol-C5-desaturase;
GN   Name=SC5D; Synonyms=SC5DL;
DR   GO; GO:0000248; F:C-5 sterol desaturase activity; TAS:ProtInc.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0050046; F:lathosterol oxidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
DR   GO; GO:0033490; P:cholesterol biosynthetic process via lathosterol; IEA:Ensembl.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SC61B_HUMAN             Reviewed;          96 AA.
AC   P60468; P38390; P38391; Q6IBC1;
DE   RecName: Full=Protein transport protein Sec61 subunit beta;
GN   Name=SEC61B;
DR   GO; GO:0048408; F:epidermal growth factor binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.
DR   GO; GO:0030970; P:retrograde protein transport, ER to cytosol; IMP:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SC61G_HUMAN             Reviewed;          68 AA.
AC   P60059; B2R4J0; P38384; Q6IB25;
DE   RecName: Full=Protein transport protein Sec61 subunit gamma;
GN   Name=SEC61G;
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; ISS:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045047; P:protein targeting to ER; ISS:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SC6A1_HUMAN             Reviewed;         599 AA.
AC   P30531; Q8N4K8;
DE   RecName: Full=Sodium- and chloride-dependent GABA transporter 1;
DE            Short=GAT-1;
DE   AltName: Full=Solute carrier family 6 member 1;
GN   Name=SLC6A1; Synonyms=GABATR, GABT1, GAT1;
DR   GuidetoPHARMACOLOGY; 929; -.
DR   GO; GO:0005332; F:gamma-aminobutyric acid:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0051939; P:gamma-aminobutyric acid import; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0014054; P:positive regulation of gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0014074; P:response to purine-containing compound; IEA:Ensembl.
DR   GO; GO:0009744; P:response to sucrose; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   SC65_HUMAN              Reviewed;         437 AA.
AC   Q92791; Q53GI6; Q9H4F6;
DE   RecName: Full=Synaptonemal complex protein SC65;
DE   AltName: Full=Leprecan-like protein 4;
DE   AltName: Full=Nucleolar autoantigen No55;
GN   Name=LEPREL4; Synonyms=NOL55, SC65;
DR   GO; GO:0007130; P:synaptonemal complex assembly; TAS:ProtInc.
//
ID   SC6A2_HUMAN             Reviewed;         617 AA.
AC   P23975; B2R707; B4DX48; Q96KH8;
DE   RecName: Full=Sodium-dependent noradrenaline transporter;
DE   AltName: Full=Norepinephrine transporter;
DE            Short=NET;
DE   AltName: Full=Solute carrier family 6 member 2;
GN   Name=SLC6A2; Synonyms=NAT1, NET1, SLC6A5;
DR   GuidetoPHARMACOLOGY; 926; -.
DR   GO; GO:0008504; F:monoamine transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0005334; F:norepinephrine:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015844; P:monoamine transport; IDA:MGI.
DR   GO; GO:0015874; P:norepinephrine transport; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC6A3_HUMAN             Reviewed;         620 AA.
AC   Q01959; A2RUN4; Q14996;
DE   RecName: Full=Sodium-dependent dopamine transporter;
DE            Short=DA transporter;
DE            Short=DAT;
DE   AltName: Full=Solute carrier family 6 member 3;
GN   Name=SLC6A3; Synonyms=DAT1;
DR   GuidetoPHARMACOLOGY; 927; -.
DR   GO; GO:0035240; F:dopamine binding; IEA:Ensembl.
DR   GO; GO:0005329; F:dopamine transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005330; F:dopamine:sodium symporter activity; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0008504; F:monoamine transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0021984; P:adenohypophysis development; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042420; P:dopamine catabolic process; IEA:Ensembl.
DR   GO; GO:0015872; P:dopamine transport; IDA:UniProtKB.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0015844; P:monoamine transport; IDA:MGI.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; TAS:Reactome.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0060134; P:prepulse inhibition; IEA:Ensembl.
DR   GO; GO:0042053; P:regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SC6A4_HUMAN             Reviewed;         630 AA.
AC   P31645; Q5EE02;
DE   RecName: Full=Sodium-dependent serotonin transporter;
DE   AltName: Full=5HT transporter;
DE            Short=5HTT;
DE   AltName: Full=Solute carrier family 6 member 4;
GN   Name=SLC6A4; Synonyms=HTT, SERT;
DR   GuidetoPHARMACOLOGY; 928; -.
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0019811; F:cocaine binding; IEA:Ensembl.
DR   GO; GO:0008504; F:monoamine transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
DR   GO; GO:0015222; F:serotonin transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0005335; F:serotonin:sodium symporter activity; IDA:UniProtKB.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0071321; P:cellular response to cGMP; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0015844; P:monoamine transport; IDA:MGI.
DR   GO; GO:0021941; P:negative regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; ISS:BHF-UCL.
DR   GO; GO:0032227; P:negative regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0006837; P:serotonin transport; IDA:UniProtKB.
DR   GO; GO:0051610; P:serotonin uptake; IDA:UniProtKB.
DR   GO; GO:0035176; P:social behavior; ISS:BHF-UCL.
DR   GO; GO:0042713; P:sperm ejaculation; IEA:Ensembl.
DR   GO; GO:0021794; P:thalamus development; IMP:UniProtKB.
DR   GO; GO:0042310; P:vasoconstriction; IEA:Ensembl.
//
ID   SC6A5_HUMAN             Reviewed;         797 AA.
AC   Q9Y345; O95288; Q4VAM7; Q9BX77;
DE   RecName: Full=Sodium- and chloride-dependent glycine transporter 2;
DE            Short=GlyT-2;
DE            Short=GlyT2;
DE   AltName: Full=Solute carrier family 6 member 5;
GN   Name=SLC6A5; Synonyms=GLYT2, NET1;
DR   GuidetoPHARMACOLOGY; 936; -.
DR   GO; GO:0015375; F:glycine:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0015816; P:glycine transport; TAS:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC6A6_HUMAN             Reviewed;         620 AA.
AC   P31641; B2RNU7; Q9BRI2; Q9BXB0;
DE   RecName: Full=Sodium- and chloride-dependent taurine transporter;
DE   AltName: Full=Solute carrier family 6 member 6;
GN   Name=SLC6A6;
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0030977; F:taurine binding; IEA:Ensembl.
DR   GO; GO:0005369; F:taurine:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015734; P:taurine transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC6A7_HUMAN             Reviewed;         636 AA.
AC   Q99884; Q0VG81; Q52LU6;
DE   RecName: Full=Sodium-dependent proline transporter;
DE   AltName: Full=Solute carrier family 6 member 7;
GN   Name=SLC6A7; Synonyms=PROT;
DR   GuidetoPHARMACOLOGY; 938; -.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0015824; P:proline transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC6A8_HUMAN             Reviewed;         635 AA.
AC   P48029; B2KY47; B4DIA3; E9PFC0; Q13032; Q66I36;
DE   RecName: Full=Sodium- and chloride-dependent creatine transporter 1;
DE            Short=CT1;
DE            Short=Creatine transporter 1;
DE   AltName: Full=Solute carrier family 6 member 8;
GN   Name=SLC6A8;
DR   GO; GO:0015220; F:choline transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005308; F:creatine transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0005309; F:creatine:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006600; P:creatine metabolic process; TAS:Reactome.
DR   GO; GO:1902598; P:creatine transmembrane transport; NAS:GOC.
DR   GO; GO:0015881; P:creatine transport; NAS:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SC6A9_HUMAN             Reviewed;         706 AA.
AC   P48067; A6NDH1; A6NII2; A6NNZ8; Q5TAB8; Q5TAB9; Q5TAC0;
DE   RecName: Full=Sodium- and chloride-dependent glycine transporter 1;
DE            Short=GlyT-1;
DE            Short=GlyT1;
DE   AltName: Full=Solute carrier family 6 member 9;
GN   Name=SLC6A9;
DR   GuidetoPHARMACOLOGY; 935; -.
DR   GO; GO:0015375; F:glycine:sodium symporter activity; TAS:ProtInc.
DR   GO; GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SCAF8_HUMAN             Reviewed;        1271 AA.
AC   Q9UPN6; Q5TBU6; Q6NSK3; Q9BQN8; Q9BX43;
DE   RecName: Full=Protein SCAF8;
DE   AltName: Full=CDC5L complex-associated protein 7;
DE   AltName: Full=RNA-binding motif protein 16;
DE   AltName: Full=SR-related and CTD-associated factor 8;
GN   Name=SCAF8; Synonyms=CCAP7, KIAA1116, RBM16;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0043175; F:RNA polymerase core enzyme binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SCAFB_HUMAN             Reviewed;        1463 AA.
AC   Q99590; A6NEU9; A6NLW5; Q8IW59;
DE   RecName: Full=Protein SCAF11;
DE   AltName: Full=CTD-associated SR protein 11;
DE   AltName: Full=Renal carcinoma antigen NY-REN-40;
DE   AltName: Full=SC35-interacting protein 1;
DE   AltName: Full=SR-related and CTD-associated factor 11;
DE   AltName: Full=SRSF2-interacting protein;
DE   AltName: Full=Serine/arginine-rich splicing factor 2-interacting protein;
DE   AltName: Full=Splicing factor, arginine/serine-rich 2-interacting protein;
DE   AltName: Full=Splicing regulatory protein 129;
DE            Short=SRrp129;
GN   Name=SCAF11; Synonyms=CASP11, SFRS2IP, SIP1, SRSF2IP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; IDA:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; IDA:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
//
ID   SCAI_HUMAN              Reviewed;         606 AA.
AC   Q8N9R8; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4;
DE   RecName: Full=Protein SCAI;
DE   AltName: Full=Suppressor of cancer cell invasion protein;
GN   Name=SCAI; Synonyms=C9orf126;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SCAM2_HUMAN             Reviewed;         329 AA.
AC   O15127; B2RDF0; Q9BQE8;
DE   RecName: Full=Secretory carrier-associated membrane protein 2;
DE            Short=Secretory carrier membrane protein 2;
GN   Name=SCAMP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
//
ID   SCAM1_HUMAN             Reviewed;         338 AA.
AC   O15126; O43587; Q6FG23; Q96BX1; Q96QK5;
DE   RecName: Full=Secretory carrier-associated membrane protein 1;
DE            Short=Secretory carrier membrane protein 1;
GN   Name=SCAMP1; Synonyms=SCAMP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IDA:UniProtKB.
//
ID   SCAM3_HUMAN             Reviewed;         347 AA.
AC   O14828; A9Z1W6; B1AVS6; O15128; Q96FR8; Q9BPY0;
DE   RecName: Full=Secretory carrier-associated membrane protein 3;
DE            Short=Secretory carrier membrane protein 3;
GN   Name=SCAMP3; Synonyms=C1orf3, PROPIN1;
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   SCAM4_HUMAN             Reviewed;         229 AA.
AC   Q969E2; Q8N2N1; Q8NAV0;
DE   RecName: Full=Secretory carrier-associated membrane protein 4;
DE            Short=Secretory carrier membrane protein 4;
GN   Name=SCAMP4;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SCAM5_HUMAN             Reviewed;         235 AA.
AC   Q8TAC9; B3KPJ7; B7Z762; D3DW71; Q8N3M4;
DE   RecName: Full=Secretory carrier-associated membrane protein 5;
DE            Short=Secretory carrier membrane protein 5;
DE            Short=hSCAMP5;
GN   Name=SCAMP5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045806; P:negative regulation of endocytosis; IDA:UniProtKB.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:UniProtKB.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
//
ID   SCAPE_HUMAN             Reviewed;        1400 AA.
AC   Q9BY12; F5H7X8; H3BNR7; Q3B7X7; Q96BS9; Q9H3D8; Q9NT03; Q9P274;
DE   RecName: Full=S phase cyclin A-associated protein in the endoplasmic reticulum;
DE            Short=S phase cyclin A-associated protein in the ER;
DE   AltName: Full=Zinc finger protein 291;
GN   Name=SCAPER; Synonyms=KIAA1454, ZNF291; ORFNames=MSTP063;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   SCAP_HUMAN              Reviewed;        1279 AA.
AC   Q12770; Q8N2E0; Q8WUA1;
DE   RecName: Full=Sterol regulatory element-binding protein cleavage-activating protein;
DE            Short=SCAP;
DE            Short=SREBP cleavage-activating protein;
GN   Name=SCAP; Synonyms=KIAA0199; ORFNames=PSEC0227;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0045541; P:negative regulation of cholesterol biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0045716; P:positive regulation of low-density lipoprotein particle receptor biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0032933; P:SREBP signaling pathway; IMP:UniProtKB.
//
ID   SCAR3_HUMAN             Reviewed;         606 AA.
AC   Q6AZY7; Q9UM15; Q9UM16;
DE   RecName: Full=Scavenger receptor class A member 3;
DE   AltName: Full=Cellular stress response gene protein;
GN   Name=SCARA3; Synonyms=CSR;
DR   GO; GO:0005044; F:scavenger receptor activity; TAS:ProtInc.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:GOC.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0009650; P:UV protection; TAS:ProtInc.
//
ID   SCAR5_HUMAN             Reviewed;         495 AA.
AC   Q6ZMJ2; Q6UXZ1; Q7Z4A1; Q8N4Z7;
DE   RecName: Full=Scavenger receptor class A member 5;
DE   AltName: Full=Scavenger receptor hlg;
GN   Name=SCARA5; ORFNames=UNQ2938/PRO28700;
DR   GO; GO:0070287; F:ferritin receptor activity; ISS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0034755; P:iron ion transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; ISS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; ISS:GOC.
//
ID   SCC4_HUMAN              Reviewed;         613 AA.
AC   Q9Y6X3; Q66PT1; Q6P3S7; Q6ZTT2; Q9UFX8;
DE   RecName: Full=MAU2 chromatid cohesion factor homolog;
DE            Short=MAU-2;
DE   AltName: Full=Cohesin loading complex subunit SCC4 homolog;
GN   Name=MAU2; Synonyms=KIAA0892, SCC4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   SCD5_HUMAN              Reviewed;         330 AA.
AC   Q86SK9; B2RPG0; Q4W5Q5; Q8NDS0; Q9H7D1;
DE   RecName: Full=Stearoyl-CoA desaturase 5;
DE            EC=1.14.19.1;
DE   AltName: Full=Acyl-CoA-desaturase 4;
DE   AltName: Full=HSCD5;
DE   AltName: Full=Stearoyl-CoA 9-desaturase;
GN   Name=SCD5; Synonyms=ACOD4, SCD4;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004768; F:stearoyl-CoA 9-desaturase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
//
ID   SCEL_HUMAN              Reviewed;         688 AA.
AC   O95171; B7Z797; F5H651; Q53H61; Q5W0S8; Q5W0S9; Q86X00;
DE   RecName: Full=Sciellin;
GN   Name=SCEL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; ISS:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
//
ID   SCFD1_HUMAN             Reviewed;         642 AA.
AC   Q8WVM8; A8K2Z5; B7Z4U7; B7Z594; O60754; O94990; Q7Z529; Q9BZI3;
AC   Q9UNL3; Q9Y6A8;
DE   RecName: Full=Sec1 family domain-containing protein 1;
DE   AltName: Full=SLY1 homolog;
DE            Short=Sly1p;
DE   AltName: Full=Syntaxin-binding protein 1-like 2;
GN   Name=SCFD1; Synonyms=C14orf163, KIAA0917, STXBP1L2; ORFNames=FKSG23;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019905; F:syntaxin binding; ISS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEP:UniProtKB.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISS:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   SCFD2_HUMAN             Reviewed;         684 AA.
AC   Q8WU76; Q8N5F3; Q8N8H0; Q96ED3;
DE   RecName: Full=Sec1 family domain-containing protein 2;
DE   AltName: Full=Syntaxin-binding protein 1-like 1;
GN   Name=SCFD2; Synonyms=STXBP1L1;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   SCF_HUMAN               Reviewed;         273 AA.
AC   P21583; A0AV09; A8K2Q4; B7ZLM4; Q16487; Q68DZ2; Q7M4N8; Q9UQK7;
DE   RecName: Full=Kit ligand;
DE   AltName: Full=Mast cell growth factor;
DE            Short=MGF;
DE   AltName: Full=Stem cell factor;
DE            Short=SCF;
DE   AltName: Full=c-Kit ligand;
DE   Contains:
DE     RecName: Full=Soluble KIT ligand;
DE              Short=sKITLG;
DE   Flags: Precursor;
GN   Name=KITLG; Synonyms=MGF, SCF;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005173; F:stem cell factor receptor binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IDA:DFLAT.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0033026; P:negative regulation of mast cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0070668; P:positive regulation of mast cell proliferation; IEA:Ensembl.
DR   GO; GO:0045636; P:positive regulation of melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002763; P:positive regulation of myeloid leukocyte differentiation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SCG1_HUMAN              Reviewed;         677 AA.
AC   P05060; A8K021; Q59EU9; Q6IBS6; Q9BQV6; Q9UC25; Q9UJA6;
DE   RecName: Full=Secretogranin-1;
DE   AltName: Full=Chromogranin-B;
DE            Short=CgB;
DE   AltName: Full=Secretogranin I;
DE            Short=SgI;
DE   Contains:
DE     RecName: Full=GAWK peptide;
DE   Contains:
DE     RecName: Full=CCB peptide;
DE   Flags: Precursor;
GN   Name=CHGB; Synonyms=SCG1;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SCG2_HUMAN              Reviewed;         617 AA.
AC   P13521; B2R662; Q53T11; Q8TBH3;
DE   RecName: Full=Secretogranin-2;
DE   AltName: Full=Chromogranin-C;
DE   AltName: Full=Secretogranin II;
DE            Short=SgII;
DE   Contains:
DE     RecName: Full=Secretoneurin;
DE              Short=SN;
DE   Flags: Precursor;
GN   Name=SCG2; Synonyms=CHGC;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:HGNC.
DR   GO; GO:0005125; F:cytokine activity; IDA:HGNC.
DR   GO; GO:0001525; P:angiogenesis; IDA:HGNC.
DR   GO; GO:0006928; P:cellular component movement; IDA:HGNC.
DR   GO; GO:0043542; P:endothelial cell migration; TAS:HGNC.
DR   GO; GO:0048245; P:eosinophil chemotaxis; IDA:HGNC.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:HGNC.
DR   GO; GO:0006954; P:inflammatory response; TAS:HGNC.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:HGNC.
DR   GO; GO:0000165; P:MAPK cascade; IDA:HGNC.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; TAS:HGNC.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:HGNC.
DR   GO; GO:0009306; P:protein secretion; TAS:ProtInc.
//
ID   SCG3_HUMAN              Reviewed;         468 AA.
AC   Q8WXD2; A8K2B0; B3KQP6; B4DK99; F5H3R8; Q96C83; Q96GE8; Q9Y6G7;
DE   RecName: Full=Secretogranin-3;
DE   AltName: Full=Secretogranin III;
DE            Short=SgIII;
DE   Flags: Precursor;
GN   Name=SCG3; ORFNames=UNQ2502/PRO5990;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   SCHI1_HUMAN             Reviewed;         487 AA.
AC   Q9P0W5; B3KRM0; O75543; Q00P30; Q00P31; Q7Z3Y3; Q8IY83; Q9P0W3;
AC   Q9P0W4;
DE   RecName: Full=Schwannomin-interacting protein 1;
DE            Short=SCHIP-1;
GN   Name=SCHIP1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SCIMP_HUMAN             Reviewed;         145 AA.
AC   Q6UWF3; A6XGL4; B4DLK1; Q96MD0;
DE   RecName: Full=SLP adapter and CSK-interacting membrane protein;
DE   AltName: Full=SLP65/SLP76, Csk-interacting membrane protein;
GN   Name=SCIMP; Synonyms=C17orf87; ORFNames=UNQ5783/PRO16090;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
//
ID   SCLT1_HUMAN             Reviewed;         688 AA.
AC   Q96NL6; A4QN04; Q0VAH2; Q6P2M4;
DE   RecName: Full=Sodium channel and clathrin linker 1;
DE   AltName: Full=Sodium channel-associated protein 1;
GN   Name=SCLT1; Synonyms=SAP1;
DR   GO; GO:0017080; F:sodium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; IEA:Ensembl.
//
ID   SCLY_HUMAN              Reviewed;         445 AA.
AC   Q96I15; B9A068; J3KN06; Q53SN1; Q53SN8; Q7L670; Q9NVT7; Q9NZR7;
DE   RecName: Full=Selenocysteine lyase;
DE            Short=hSCL;
DE            EC=4.4.1.16;
GN   Name=SCLY; Synonyms=SCL;
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009000; F:selenocysteine lyase activity; TAS:ProtInc.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
//
ID   SCMC1_HUMAN             Reviewed;         477 AA.
AC   Q6NUK1; B7ZAI9; Q5T331; Q5T485; Q6PJJ9; Q705K4; Q9P129;
DE   RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-1;
DE   AltName: Full=Mitochondrial ATP-Mg/Pi carrier protein 1;
DE   AltName: Full=Mitochondrial Ca(2+)-dependent solute carrier protein 1;
DE   AltName: Full=Small calcium-binding mitochondrial carrier protein 1;
DE   AltName: Full=Solute carrier family 25 member 24;
GN   Name=SLC25A24; Synonyms=APC1, MCSC1, SCAMC1;
DR   GO; GO:0005347; F:ATP transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0015867; P:ATP transport; IMP:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IMP:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0006839; P:mitochondrial transport; IMP:UniProtKB.
DR   GO; GO:0010941; P:regulation of cell death; IMP:UniProtKB.
//
ID   SCMC2_HUMAN             Reviewed;         469 AA.
AC   Q6KCM7; Q5SYW7; Q5SYW8; Q5SYX3; Q5VWU2; Q5VWU3; Q5VWU4; Q6KCM4;
AC   Q6KCM6; Q6UX48; Q705K2; Q96PZ1; Q9BSA6;
DE   RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-2;
DE   AltName: Full=Mitochondrial ATP-Mg/Pi carrier protein 3;
DE   AltName: Full=Mitochondrial Ca(2+)-dependent solute carrier protein 3;
DE   AltName: Full=Small calcium-binding mitochondrial carrier protein 2;
DE   AltName: Full=Solute carrier family 25 member 25;
GN   Name=SLC25A25; Synonyms=APC3, KIAA1896, MCSC3, SCAMC2;
GN   ORFNames=UNQ549/PRO1106;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0045333; P:cellular respiration; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
//
ID   SCMC3_HUMAN             Reviewed;         468 AA.
AC   Q9BV35; B4DGB6; Q4LBC2; Q705K3; Q86Y43; Q8N2N4; Q96NQ4;
DE   RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-3;
DE   AltName: Full=Mitochondrial ATP-Mg/Pi carrier protein 2;
DE   AltName: Full=Mitochondrial Ca(2+)-dependent solute carrier protein 2;
DE   AltName: Full=Small calcium-binding mitochondrial carrier protein 3;
DE   AltName: Full=Solute carrier family 25 member 23;
GN   Name=SLC25A23; Synonyms=APC2, MCSC2, SCAMC3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SCMH1_HUMAN             Reviewed;         660 AA.
AC   Q96GD3; B4DRQ8; Q5VT76; Q6IAJ4; Q8WU48; Q9UKM5; Q9UKM6;
DE   RecName: Full=Polycomb protein SCMH1;
DE   AltName: Full=Sex comb on midleg homolog 1;
GN   Name=SCMH1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0016458; P:gene silencing; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SCML1_HUMAN             Reviewed;         329 AA.
AC   Q9UN30; B0FZN6; B2RA08; Q5H968; Q5H969;
DE   RecName: Full=Sex comb on midleg-like protein 1;
GN   Name=SCML1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SCML2_HUMAN             Reviewed;         700 AA.
AC   Q9UQR0; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5;
DE   RecName: Full=Sex comb on midleg-like protein 2;
GN   Name=SCML2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SCML4_HUMAN             Reviewed;         414 AA.
AC   Q8N228; B0QZ10; B0QZ11; B7ZBX3; Q5JXD0; Q5T0T6; Q8IYY6;
DE   RecName: Full=Sex comb on midleg-like protein 4;
GN   Name=SCML4;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SCN1A_HUMAN             Reviewed;        2009 AA.
AC   P35498; E9PG49; Q16172; Q585T7; Q8IUJ6; Q96LA3; Q9C008;
DE   RecName: Full=Sodium channel protein type 1 subunit alpha;
DE   AltName: Full=Sodium channel protein brain I subunit alpha;
DE   AltName: Full=Sodium channel protein type I subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.1;
GN   Name=SCN1A; Synonyms=NAC1, SCN1;
DR   GuidetoPHARMACOLOGY; 578; -.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; NAS:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0019227; P:neuronal action potential propagation; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
//
ID   SCN1B_HUMAN             Reviewed;         218 AA.
AC   Q07699; Q5TZZ4; Q6TN97;
DE   RecName: Full=Sodium channel subunit beta-1;
DE   Flags: Precursor;
GN   Name=SCN1B;
DR   GO; GO:0019871; F:sodium channel inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IDA:BHF-UCL.
DR   GO; GO:0086006; F:voltage-gated sodium channel activity involved in cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0086062; F:voltage-gated sodium channel activity involved in Purkinje myocyte action potential; IMP:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; ISS:BHF-UCL.
DR   GO; GO:0061337; P:cardiac conduction; ISS:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0021966; P:corticospinal neuron axon guidance; ISS:BHF-UCL.
DR   GO; GO:0040011; P:locomotion; ISS:BHF-UCL.
DR   GO; GO:0051899; P:membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; ISS:BHF-UCL.
DR   GO; GO:0086047; P:membrane depolarization during Purkinje myocyte cell action potential; IMP:BHF-UCL.
DR   GO; GO:0019227; P:neuronal action potential propagation; ISS:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IDA:BHF-UCL.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; ISS:BHF-UCL.
DR   GO; GO:0046684; P:response to pyrethroid; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   SCN2A_HUMAN             Reviewed;        2005 AA.
AC   Q99250; A6NC14; A6NIQ5; Q14472; Q53T77; Q9BZC9; Q9BZD0;
DE   RecName: Full=Sodium channel protein type 2 subunit alpha;
DE   AltName: Full=HBSC II;
DE   AltName: Full=Sodium channel protein brain II subunit alpha;
DE   AltName: Full=Sodium channel protein type II subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.2;
GN   Name=SCN2A; Synonyms=NAC2, SCN2A1, SCN2A2;
DR   GuidetoPHARMACOLOGY; 579; -.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; ISS:UniProtKB.
DR   GO; GO:0008627; P:intrinsic apoptotic signaling pathway in response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0042552; P:myelination; ISS:BHF-UCL.
DR   GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   SCN2B_HUMAN             Reviewed;         215 AA.
AC   O60939; O75302; Q9UNN3;
DE   RecName: Full=Sodium channel subunit beta-2;
DE   Flags: Precursor;
GN   Name=SCN2B; ORFNames=UNQ326/PRO386;
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0086006; F:voltage-gated sodium channel activity involved in cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; IMP:GOC.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0046684; P:response to pyrethroid; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   SCN3A_HUMAN             Reviewed;        2000 AA.
AC   Q9NY46; Q16142; Q53SX0; Q9BZB3; Q9C006; Q9NYK2; Q9P2J1; Q9UPD1;
AC   Q9Y6P4;
DE   RecName: Full=Sodium channel protein type 3 subunit alpha;
DE   AltName: Full=Sodium channel protein brain III subunit alpha;
DE   AltName: Full=Sodium channel protein type III subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subtype III;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.3;
GN   Name=SCN3A; Synonyms=KIAA1356, NAC3;
DR   GuidetoPHARMACOLOGY; 580; -.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; NAS:UniProtKB.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
//
ID   SCN3B_HUMAN             Reviewed;         215 AA.
AC   Q9NY72; A5H1I5; Q17RL3; Q9ULR2;
DE   RecName: Full=Sodium channel subunit beta-3;
DE   Flags: Precursor;
GN   Name=SCN3B; Synonyms=KIAA1158;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:BHF-UCL.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; NAS:UniProtKB.
DR   GO; GO:0086006; F:voltage-gated sodium channel activity involved in cardiac muscle cell action potential; IDA:BHF-UCL.
DR   GO; GO:0086014; P:atrial cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0051899; P:membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0010460; P:positive regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IDA:BHF-UCL.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IMP:BHF-UCL.
DR   GO; GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0086070; P:SA node cell to atrial cardiac muscle cell communication; ISS:BHF-UCL.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   SCN4A_HUMAN             Reviewed;        1836 AA.
AC   P35499; Q15478; Q16447; Q7Z6B1;
DE   RecName: Full=Sodium channel protein type 4 subunit alpha;
DE   AltName: Full=SkM1;
DE   AltName: Full=Sodium channel protein skeletal muscle subunit alpha;
DE   AltName: Full=Sodium channel protein type IV subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.4;
GN   Name=SCN4A;
DR   GuidetoPHARMACOLOGY; 581; -.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   SCN4B_HUMAN             Reviewed;         228 AA.
AC   Q8IWT1; E9PPT5; Q6PIG5;
DE   RecName: Full=Sodium channel subunit beta-4;
DE   Flags: Precursor;
GN   Name=SCN4B;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IDA:UniProtKB.
DR   GO; GO:0086006; F:voltage-gated sodium channel activity involved in cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0086067; P:AV node cell to bundle of His cell communication; IMP:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IDA:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; IDA:UniProtKB.
//
ID   SCN5A_HUMAN             Reviewed;        2016 AA.
AC   Q14524; A5H1P8; A6N922; A6N923; B2RTU0; E7ET19; E9PEF3; E9PEK2;
AC   E9PFW7; Q59H93; Q75RX9; Q75RY0; Q86UR3; Q8IZC9; Q96J69;
DE   RecName: Full=Sodium channel protein type 5 subunit alpha;
DE   AltName: Full=HH1;
DE   AltName: Full=Sodium channel protein cardiac muscle subunit alpha;
DE   AltName: Full=Sodium channel protein type V subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.5;
GN   Name=SCN5A;
DR   GuidetoPHARMACOLOGY; 582; -.
DR   GO; GO:0030506; F:ankyrin binding; IDA:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; IPI:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0050998; F:nitric-oxide synthase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IDA:UniProtKB.
DR   GO; GO:0086006; F:voltage-gated sodium channel activity involved in cardiac muscle cell action potential; IDA:BHF-UCL.
DR   GO; GO:0086067; P:AV node cell to bundle of His cell communication; IMP:BHF-UCL.
DR   GO; GO:0003360; P:brainstem development; ISS:BHF-UCL.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0086002; P:cardiac muscle cell action potential involved in contraction; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0003231; P:cardiac ventricle development; ISS:BHF-UCL.
DR   GO; GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; ISS:BHF-UCL.
DR   GO; GO:0051899; P:membrane depolarization; IDA:BHF-UCL.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IDA:BHF-UCL.
DR   GO; GO:0086012; P:membrane depolarization during cardiac muscle cell action potential; IMP:BHF-UCL.
DR   GO; GO:0086046; P:membrane depolarization during SA node cell action potential; ISS:BHF-UCL.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:BHF-UCL.
DR   GO; GO:0045760; P:positive regulation of action potential; ISS:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IDA:BHF-UCL.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0060372; P:regulation of atrial cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IMP:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0086091; P:regulation of heart rate by cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0014894; P:response to denervation involved in regulation of muscle adaptation; ISS:BHF-UCL.
DR   GO; GO:0086070; P:SA node cell to atrial cardiac muscle cell communication; IMP:BHF-UCL.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; IDA:UniProtKB.
DR   GO; GO:0021537; P:telencephalon development; ISS:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   SCN7A_HUMAN             Reviewed;        1682 AA.
AC   Q01118;
DE   RecName: Full=Sodium channel protein type 7 subunit alpha;
DE   AltName: Full=Putative voltage-gated sodium channel subunit alpha Nax;
DE   AltName: Full=Sodium channel protein cardiac and skeletal muscle subunit alpha;
DE   AltName: Full=Sodium channel protein type VII subunit alpha;
GN   Name=SCN7A; Synonyms=SCN6A;
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0055078; P:sodium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   SCN8A_HUMAN             Reviewed;        1980 AA.
AC   Q9UQD0; B9VWG8; O95788; Q9NYX2; Q9UPB2;
DE   RecName: Full=Sodium channel protein type 8 subunit alpha;
DE   AltName: Full=Sodium channel protein type VIII subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.6;
GN   Name=SCN8A; Synonyms=MED;
DR   GuidetoPHARMACOLOGY; 583; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IDA:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0007517; P:muscle organ development; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0007422; P:peripheral nervous system development; ISS:BHF-UCL.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006814; P:sodium ion transport; NAS:UniProtKB.
//
ID   SCN9A_HUMAN             Reviewed;        1988 AA.
AC   Q15858; A1BUH5; Q6B4R9; Q6B4S0; Q6B4S1; Q70HX1; Q70HX2; Q8WTU1;
AC   Q8WWN4;
DE   RecName: Full=Sodium channel protein type 9 subunit alpha;
DE   AltName: Full=Neuroendocrine sodium channel;
DE            Short=hNE-Na;
DE   AltName: Full=Peripheral sodium channel 1;
DE            Short=PN1;
DE   AltName: Full=Sodium channel protein type IX subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.7;
GN   Name=SCN9A; Synonyms=NENA;
DR   GuidetoPHARMACOLOGY; 584; -.
DR   GO; GO:0031402; F:sodium ion binding; IEA:Ensembl.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:RefGenome.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   SCNAA_HUMAN             Reviewed;        1956 AA.
AC   Q9Y5Y9; A6NDQ1;
DE   RecName: Full=Sodium channel protein type 10 subunit alpha;
DE   AltName: Full=Peripheral nerve sodium channel 3;
DE            Short=PN3;
DE            Short=hPN3;
DE   AltName: Full=Sodium channel protein type X subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.8;
GN   Name=SCN10A;
DR   GuidetoPHARMACOLOGY; 585; -.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IDA:BHF-UCL.
DR   GO; GO:0086067; P:AV node cell to bundle of His cell communication; IMP:BHF-UCL.
DR   GO; GO:0086069; P:bundle of His cell to Purkinje myocyte communication; IMP:BHF-UCL.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0060371; P:regulation of atrial cardiac muscle cell membrane depolarization; IMP:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   SCNBA_HUMAN             Reviewed;        1791 AA.
AC   Q9UI33; A6NN05; C9JD48; C9JR31; Q68K15; Q8NDX3; Q9UHE0; Q9UHM0;
DE   RecName: Full=Sodium channel protein type 11 subunit alpha;
DE   AltName: Full=Peripheral nerve sodium channel 5;
DE            Short=PN5;
DE   AltName: Full=Sensory neuron sodium channel 2;
DE   AltName: Full=Sodium channel protein type XI subunit alpha;
DE   AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.9;
DE   AltName: Full=hNaN;
GN   Name=SCN11A; Synonyms=SCN12A, SNS2;
DR   GuidetoPHARMACOLOGY; 586; -.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0019228; P:neuronal action potential; IBA:RefGenome.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
//
ID   SCND1_HUMAN             Reviewed;         179 AA.
AC   P57086; Q6IAG7;
DE   RecName: Full=SCAN domain-containing protein 1;
GN   Name=SCAND1; Synonyms=SDP1;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   SCND2_HUMAN             Reviewed;         306 AA.
AC   Q9GZW5; A8K374; Q9H9G1;
DE   RecName: Full=Putative SCAN domain-containing protein SCAND2P;
DE   AltName: Full=SCAN domain-containing protein 2 pseudogene;
GN   Name=SCAND2P; Synonyms=SCAND2;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   SCND3_HUMAN             Reviewed;        1325 AA.
AC   Q6R2W3; Q2NKL9; Q5SRJ3; Q8TCN2; Q96MV9; Q96PW3;
DE   RecName: Full=SCAN domain-containing protein 3;
DE   AltName: Full=Protein ZNF452;
DE   AltName: Full=Transposon-derived Buster4 transposase-like protein;
DE   AltName: Full=Zinc finger BED domain-containing protein 9;
GN   Name=SCAND3; Synonyms=Buster4, KIAA1925, ZBED9, ZNF305P2, ZNF452;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
//
ID   SCNM1_HUMAN             Reviewed;         230 AA.
AC   Q9BWG6; B4DWR1; Q5JR74;
DE   RecName: Full=Sodium channel modifier 1;
GN   Name=SCNM1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SCNNA_HUMAN             Reviewed;         669 AA.
AC   P37088; A5X2U9; B4E2Q5; C5HTZ0; O43271; Q6GSQ6; Q9UM64;
DE   RecName: Full=Amiloride-sensitive sodium channel subunit alpha;
DE   AltName: Full=Alpha-NaCH;
DE   AltName: Full=Epithelial Na(+) channel subunit alpha;
DE            Short=Alpha-ENaC;
DE            Short=ENaCA;
DE   AltName: Full=Nonvoltage-gated sodium channel 1 subunit alpha;
DE   AltName: Full=SCNEA;
GN   Name=SCNN1A; Synonyms=SCNN1;
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IPI:BHF-UCL.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IDA:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
DR   GO; GO:0055078; P:sodium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SCNNB_HUMAN             Reviewed;         640 AA.
AC   P51168; C5HTZ2; O60891; Q96KG2; Q9UJ32; Q9UMU5;
DE   RecName: Full=Amiloride-sensitive sodium channel subunit beta;
DE   AltName: Full=Beta-NaCH;
DE   AltName: Full=Epithelial Na(+) channel subunit beta;
DE            Short=Beta-ENaC;
DE            Short=ENaCB;
DE   AltName: Full=Nonvoltage-gated sodium channel 1 subunit beta;
DE   AltName: Full=SCNEB;
GN   Name=SCNN1B;
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IPI:BHF-UCL.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IDA:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
DR   GO; GO:0055078; P:sodium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SCNND_HUMAN             Reviewed;         638 AA.
AC   P51172; A9Z1X6; B1PS44; Q08AQ3; Q09HT0; Q5T7L3; Q8NA24;
DE   RecName: Full=Amiloride-sensitive sodium channel subunit delta;
DE   AltName: Full=Delta-NaCH;
DE   AltName: Full=Epithelial Na(+) channel subunit delta;
DE            Short=Delta-ENaC;
DE            Short=ENaCD;
DE   AltName: Full=Nonvoltage-gated sodium channel 1 subunit delta;
DE   AltName: Full=SCNED;
GN   Name=SCNN1D; Synonyms=DNACH;
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SCNNG_HUMAN             Reviewed;         649 AA.
AC   P51170; P78437; Q6PCC2; Q93023; Q93024; Q93025; Q93026; Q93027;
AC   Q96TD2;
DE   RecName: Full=Amiloride-sensitive sodium channel subunit gamma;
DE   AltName: Full=Epithelial Na(+) channel subunit gamma;
DE            Short=ENaCG;
DE            Short=Gamma-ENaC;
DE   AltName: Full=Gamma-NaCH;
DE   AltName: Full=Nonvoltage-gated sodium channel 1 subunit gamma;
DE   AltName: Full=SCNEG;
GN   Name=SCNN1G;
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005272; F:sodium channel activity; TAS:ProtInc.
DR   GO; GO:0050699; F:WW domain binding; IPI:BHF-UCL.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050891; P:multicellular organismal water homeostasis; IDA:UniProtKB.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
DR   GO; GO:0055078; P:sodium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SCO1_HUMAN              Reviewed;         301 AA.
AC   O75880; B2RDM0;
DE   RecName: Full=Protein SCO1 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=SCO1; Synonyms=SCOD1;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; IEA:InterPro.
DR   GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; TAS:ProtInc.
//
ID   SCO2_HUMAN              Reviewed;         266 AA.
AC   O43819; Q3T1B5; Q9UK87;
DE   RecName: Full=Protein SCO2 homolog, mitochondrial;
DE   Flags: Precursor;
GN   Name=SCO2;
DR   GO; GO:0005507; F:copper ion binding; NAS:UniProtKB.
DR   GO; GO:0006878; P:cellular copper ion homeostasis; IEA:InterPro.
DR   GO; GO:0006825; P:copper ion transport; IEA:InterPro.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0003012; P:muscle system process; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; IEA:Ensembl.
DR   GO; GO:0022904; P:respiratory electron transport chain; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
//
ID   SCOC_HUMAN              Reviewed;         159 AA.
AC   Q9UIL1; B7WPH7; D3DNY7; E9PB65; Q6P5T9; Q7L2Y0; Q7Z4P2; Q96JY9;
AC   Q9BZB2;
DE   RecName: Full=Short coiled-coil protein;
GN   Name=SCOC; Synonyms=SCOCO; ORFNames=HRIHFB2072;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IDA:BHF-UCL.
//
ID   SCOT1_HUMAN             Reviewed;         520 AA.
AC   P55809; B2R5V2;
DE   RecName: Full=Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial;
DE            EC=2.8.3.5;
DE   AltName: Full=3-oxoacid CoA-transferase 1;
DE   AltName: Full=Somatic-type succinyl-CoA:3-oxoacid CoA-transferase;
DE            Short=SCOT-s;
DE   Flags: Precursor;
GN   Name=OXCT1; Synonyms=OXCT, SCOT;
DR   GO; GO:0008260; F:3-oxoacid CoA-transferase activity; IMP:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0046950; P:cellular ketone body metabolic process; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071229; P:cellular response to acid; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0046952; P:ketone body catabolic process; TAS:Reactome.
DR   GO; GO:0042182; P:ketone catabolic process; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SCOT2_HUMAN             Reviewed;         517 AA.
AC   Q9BYC2; B2RBB4; Q5QPK4; Q8NHR1; Q9H1I4;
DE   RecName: Full=Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial;
DE            EC=2.8.3.5;
DE   AltName: Full=3-oxoacid CoA-transferase 2A;
DE   AltName: Full=Testis-specific succinyl-CoA:3-oxoacid CoA-transferase;
DE            Short=SCOT-t;
DE   Flags: Precursor;
GN   Name=OXCT2; ORFNames=FKSG25;
DR   GO; GO:0008260; F:3-oxoacid CoA-transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046952; P:ketone body catabolic process; IEA:InterPro.
//
ID   SCP2D_HUMAN             Reviewed;         156 AA.
AC   Q9UJQ7; Q548A4;
DE   RecName: Full=SCP2 sterol-binding domain-containing protein 1;
GN   Name=SCP2D1; Synonyms=C20orf79;
DR   GO; GO:0032934; F:sterol binding; IEA:InterPro.
//
ID   SCPDL_HUMAN             Reviewed;         429 AA.
AC   Q8NBX0; Q8TAR0; Q9Y363;
DE   RecName: Full=Saccharopine dehydrogenase-like oxidoreductase;
DE            EC=1.-.-.-;
GN   Name=SCCPDH; ORFNames=CGI-49;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
//
ID   SCRB1_HUMAN             Reviewed;         552 AA.
AC   Q8WTV0; F8W8N0; Q14016; Q52LZ5; Q6KFX4;
DE   RecName: Full=Scavenger receptor class B member 1;
DE            Short=SRB1;
DE   AltName: Full=CD36 and LIMPII analogous 1;
DE            Short=CLA-1;
DE   AltName: Full=CD36 antigen-like 1;
DE   AltName: Full=Collagen type I receptor, thrombospondin receptor-like 1;
DE   AltName: Full=SR-BI;
DE   AltName: CD_antigen=CD36;
GN   Name=SCARB1; Synonyms=CD36L1, CLA1;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; TAS:BHF-UCL.
DR   GO; GO:0034186; F:apolipoprotein A-I binding; IPI:BHF-UCL.
DR   GO; GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0008035; F:high-density lipoprotein particle binding; IEA:Ensembl.
DR   GO; GO:0070506; F:high-density lipoprotein particle receptor activity; IDA:BHF-UCL.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:BHF-UCL.
DR   GO; GO:0001875; F:lipopolysaccharide receptor activity; IDA:BHF-UCL.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:BHF-UCL.
DR   GO; GO:0001786; F:phosphatidylserine binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0051856; ?:?; IMP:BHF-UCL.
DR   GO; GO:0006702; P:androgen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0006707; P:cholesterol catabolic process; IEA:Ensembl.
DR   GO; GO:0033344; P:cholesterol efflux; ISS:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:BHF-UCL.
DR   GO; GO:0070508; P:cholesterol import; ISS:BHF-UCL.
DR   GO; GO:0032497; P:detection of lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0001935; P:endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0034384; P:high-density lipoprotein particle clearance; IDA:BHF-UCL.
DR   GO; GO:0034375; P:high-density lipoprotein particle remodeling; ISS:BHF-UCL.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IDA:BHF-UCL.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:GOC.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0034383; P:low-density lipoprotein particle clearance; ISS:BHF-UCL.
DR   GO; GO:0015914; P:phospholipid transport; ISS:BHF-UCL.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; IDA:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; TAS:BHF-UCL.
DR   GO; GO:0051000; P:positive regulation of nitric-oxide synthase activity; IDA:BHF-UCL.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:GOC.
DR   GO; GO:0043654; P:recognition of apoptotic cell; IDA:BHF-UCL.
DR   GO; GO:0050764; P:regulation of phagocytosis; IC:BHF-UCL.
DR   GO; GO:0010899; P:regulation of phosphatidylcholine catabolic process; ISS:BHF-UCL.
DR   GO; GO:0043691; P:reverse cholesterol transport; IEP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070328; P:triglyceride homeostasis; ISS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; TAS:BHF-UCL.
//
ID   SCRB2_HUMAN             Reviewed;         478 AA.
AC   Q14108; B4DKD8; E7EM68; Q53Y63;
DE   RecName: Full=Lysosome membrane protein 2;
DE   AltName: Full=85 kDa lysosomal membrane sialoglycoprotein;
DE            Short=LGP85;
DE   AltName: Full=CD36 antigen-like 2;
DE   AltName: Full=Lysosome membrane protein II;
DE            Short=LIMP II;
DE   AltName: Full=Scavenger receptor class B member 2;
DE   AltName: CD_antigen=CD36;
GN   Name=SCARB2; Synonyms=CD36L2, LIMP2, LIMPII;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0006622; P:protein targeting to lysosome; IMP:BHF-UCL.
//
ID   SCRG1_HUMAN             Reviewed;          98 AA.
AC   O75711;
DE   RecName: Full=Scrapie-responsive protein 1;
DE   AltName: Full=Scrapie-responsive gene 1 protein;
DE            Short=ScRG-1;
DE   Flags: Precursor;
GN   Name=SCRG1; ORFNames=UNQ390/PRO725;
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   SCRIB_HUMAN             Reviewed;        1630 AA.
AC   Q14160; Q6P496; Q7Z5D1; Q8WWV8; Q96C69; Q96GG1;
DE   RecName: Full=Protein scribble homolog;
DE            Short=Scribble;
DE            Short=hScrib;
DE   AltName: Full=Protein LAP4;
GN   Name=SCRIB; Synonyms=CRIB1, KIAA0147, LAP4, SCRB1, VARTUL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.
DR   GO; GO:0060561; P:apoptotic process involved in morphogenesis; IMP:UniProtKB.
DR   GO; GO:0043615; P:astrocyte cell migration; IEA:Ensembl.
DR   GO; GO:0008105; P:asymmetric protein localization; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IGI:UniProtKB.
DR   GO; GO:0035089; P:establishment of apical/basal cell polarity; IMP:UniProtKB.
DR   GO; GO:0060603; P:mammary gland duct morphogenesis; ISS:UniProtKB.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IMP:UniProtKB.
DR   GO; GO:0050918; P:positive chemotaxis; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IMP:UniProtKB.
DR   GO; GO:0071896; P:protein localization to adherens junction; IMP:BHF-UCL.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:Ensembl.
DR   GO; GO:0016080; P:synaptic vesicle targeting; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   SCRN1_HUMAN             Reviewed;         414 AA.
AC   Q12765; A8K0E9; B4DHM0; B4DIP5; C9JPG0; Q25QX7; Q8IWD1;
DE   RecName: Full=Secernin-1;
GN   Name=SCRN1; Synonyms=KIAA0193;
DR   GO; GO:0016805; F:dipeptidase activity; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; ISS:UniProtKB.
//
ID   SCRN2_HUMAN             Reviewed;         425 AA.
AC   Q96FV2; A8K3N1; B7Z8S7; E9PBV5; Q96AC3; Q9BU04;
DE   RecName: Full=Secernin-2;
GN   Name=SCRN2;
DR   GO; GO:0016805; F:dipeptidase activity; IEA:InterPro.
//
ID   SCRN3_HUMAN             Reviewed;         424 AA.
AC   Q0VDG4; B4DI11; C9JPC1; D3DPE0; Q7L1C5; Q9H5R5;
DE   RecName: Full=Secernin-3;
GN   Name=SCRN3;
DR   GO; GO:0016805; F:dipeptidase activity; IEA:InterPro.
//
ID   SCRT1_HUMAN             Reviewed;         348 AA.
AC   Q9BWW7; A8MX66; Q96C52;
DE   RecName: Full=Transcriptional repressor scratch 1;
DE   AltName: Full=Scratch homolog 1 zinc finger protein;
DE            Short=SCRT;
DE            Short=Scratch 1;
DE            Short=hScrt;
GN   Name=SCRT1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SCRT2_HUMAN             Reviewed;         307 AA.
AC   Q9NQ03;
DE   RecName: Full=Transcriptional repressor scratch 2;
DE   AltName: Full=Scratch homolog 2 zinc finger protein;
GN   Name=SCRT2; ORFNames=FP7030;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IC:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
//
ID   SCTM1_HUMAN             Reviewed;         248 AA.
AC   Q8WVN6; B2R7H0; O00466;
DE   RecName: Full=Secreted and transmembrane protein 1;
DE   AltName: Full=Protein K-12;
DE   Flags: Precursor;
GN   Name=SECTM1; Synonyms=K12;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   SCTR_HUMAN              Reviewed;         440 AA.
AC   P47872; Q12961; Q13213; Q53T00;
DE   RecName: Full=Secretin receptor;
DE            Short=SCT-R;
DE   Flags: Precursor;
GN   Name=SCTR;
DR   GuidetoPHARMACOLOGY; 252; -.
DR   GO; GO:0015055; F:secretin receptor activity; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   SCUB1_HUMAN             Reviewed;         988 AA.
AC   Q8IWY4; Q5R336;
DE   RecName: Full=Signal peptide, CUB and EGF-like domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=SCUBE1;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:MGI.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007512; P:adult heart development; NAS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; NAS:UniProtKB.
DR   GO; GO:0045446; P:endothelial cell differentiation; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; NAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:UniProtKB.
//
ID   SCUB2_HUMAN             Reviewed;         999 AA.
AC   Q9NQ36; Q2NKQ8; Q6ZWI1;
DE   RecName: Full=Signal peptide, CUB and EGF-like domain-containing protein 2;
DE   AltName: Full=Protein CEGP1;
DE   Flags: Precursor;
GN   Name=SCUBE2; Synonyms=CEGP1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   SCUB3_HUMAN             Reviewed;         993 AA.
AC   Q8IX30; A8K5A3; Q5CZB3; Q86UZ9; Q8NAU9;
DE   RecName: Full=Signal peptide, CUB and EGF-like domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=SCUBE3; Synonyms=CEGF3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IPI:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   SCX_HUMAN               Reviewed;         201 AA.
AC   Q7RTU7;
DE   RecName: Full=Basic helix-loop-helix transcription factor scleraxis;
DE   AltName: Full=Class A basic helix-loop-helix protein 41;
DE            Short=bHLHa41;
DE   AltName: Full=Class A basic helix-loop-helix protein 48;
DE            Short=bHLHa48;
GN   Name=SCXA; Synonyms=BHLHA41, SCX;
GN   and
GN   Name=SCXB; Synonyms=BHLHA48, SCX;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0030199; P:collagen fibril organization; ISS:UniProtKB.
DR   GO; GO:0035993; P:deltoid tuberosity development; ISS:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; ISS:UniProtKB.
DR   GO; GO:0003188; P:heart valve formation; ISS:UniProtKB.
DR   GO; GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001707; P:mesoderm formation; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0061036; P:positive regulation of cartilage development; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; ISS:UniProtKB.
DR   GO; GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0061035; P:regulation of cartilage development; ISS:UniProtKB.
DR   GO; GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.
DR   GO; GO:0035990; P:tendon cell differentiation; ISS:UniProtKB.
DR   GO; GO:0035989; P:tendon development; ISS:UniProtKB.
DR   GO; GO:0035992; P:tendon formation; ISS:UniProtKB.
DR   GO; GO:0001894; P:tissue homeostasis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   SCYL2_HUMAN             Reviewed;         929 AA.
AC   Q6P3W7; A8KAB5; Q96EF4; Q96ST4; Q9H7V5; Q9NVH3; Q9P2I7;
DE   RecName: Full=SCY1-like protein 2;
DE   AltName: Full=Coated vesicle-associated kinase of 104 kDa;
GN   Name=SCYL2; Synonyms=CVAK104, KIAA1360;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008333; P:endosome to lysosome transport; IDA:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:2000370; P:positive regulation of clathrin-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:2000286; P:receptor internalization involved in canonical Wnt signaling pathway; IDA:BHF-UCL.
//
ID   SDA1_HUMAN              Reviewed;         687 AA.
AC   Q9NVU7; Q32Q11; Q68D52; Q7Z5U4; Q9H831; Q9H9P6;
DE   RecName: Full=Protein SDA1 homolog;
DE   AltName: Full=Nucleolar protein 130;
DE   AltName: Full=SDA1 domain-containing protein 1;
DE            Short=hSDA;
GN   Name=SDAD1; Synonyms=NUC130;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; ISS:UniProtKB.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:InterPro.
//
ID   SDC1_HUMAN              Reviewed;         310 AA.
AC   P18827; D6W523; Q53QV0; Q546D3; Q96HB7;
DE   RecName: Full=Syndecan-1;
DE            Short=SYND1;
DE   AltName: CD_antigen=CD138;
DE   Flags: Precursor;
GN   Name=SDC1; Synonyms=SDC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0042157; P:lipoprotein metabolic process; TAS:Reactome.
DR   GO; GO:0048627; P:myoblast development; ISS:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055002; P:striated muscle cell development; IEP:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   SDC2_HUMAN              Reviewed;         201 AA.
AC   P34741; B3KQA3; Q6PIS6; Q9H6V1;
DE   RecName: Full=Syndecan-2;
DE            Short=SYND2;
DE   AltName: Full=Fibroglycan;
DE   AltName: Full=Heparan sulfate proteoglycan core protein;
DE            Short=HSPG;
DE   AltName: CD_antigen=CD362;
DE   Flags: Precursor;
GN   Name=SDC2; Synonyms=HSPG1;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.
DR   GO; GO:0031000; P:response to caffeine; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   SDC3_HUMAN              Reviewed;         442 AA.
AC   O75056; Q5T1Z6; Q5T1Z7; Q96CT3; Q96PR8;
DE   RecName: Full=Syndecan-3;
DE            Short=SYND3;
GN   Name=SDC3; Synonyms=KIAA0468;
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SDC4_HUMAN              Reviewed;         198 AA.
AC   P31431; O00773; Q16833; Q53FN9; Q6FGN3;
DE   RecName: Full=Syndecan-4;
DE            Short=SYND4;
DE   AltName: Full=Amphiglycan;
DE   AltName: Full=Ryudocan core protein;
DE   Flags: Precursor;
GN   Name=SDC4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070053; F:thrombospondin receptor activity; IMP:BHF-UCL.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   SDCB1_HUMAN             Reviewed;         298 AA.
AC   O00560; B2R5Q7; B4DUH3; B7ZLN2; O00173; O43391; Q14CP2;
DE   RecName: Full=Syntenin-1;
DE   AltName: Full=Melanoma differentiation-associated protein 9;
DE            Short=MDA-9;
DE   AltName: Full=Pro-TGF-alpha cytoplasmic domain-interacting protein 18;
DE            Short=TACIP18;
DE   AltName: Full=Scaffold protein Pbp1;
DE   AltName: Full=Syndecan-binding protein 1;
GN   Name=SDCBP; Synonyms=MDA9, SYCL;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.
DR   GO; GO:0005109; F:frizzled binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005137; F:interleukin-5 receptor binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0045545; F:syndecan binding; NAS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IC:BHF-UCL.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006612; P:protein targeting to membrane; NAS:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0006930; P:substrate-dependent cell migration, cell extension; NAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
//
ID   SDCB2_HUMAN             Reviewed;         292 AA.
AC   Q9H190; O95892; Q5W0X1; Q9BZ42; Q9H567; Q9NRY8;
DE   RecName: Full=Syntenin-2;
DE   AltName: Full=Syndecan-binding protein 2;
GN   Name=SDCBP2; Synonyms=SITAC18;
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0046907; P:intracellular transport; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
//
ID   SDCG3_HUMAN             Reviewed;         435 AA.
AC   Q96C92; A6NCP1; O60525; Q5SXN1; Q5SXN2; Q5SXN3; Q5SXN4; Q5SXN8;
AC   Q6V704; Q9NVY5;
DE   RecName: Full=Serologically defined colon cancer antigen 3;
DE   AltName: Full=Antigen NY-CO-3;
GN   Name=SDCCAG3;
//
ID   SDCG8_HUMAN             Reviewed;         713 AA.
AC   Q86SQ7; O60527; Q3ZCR6; Q8N5F2; Q9P0F1;
DE   RecName: Full=Serologically defined colon cancer antigen 8;
DE   AltName: Full=Antigen NY-CO-8;
DE   AltName: Full=Centrosomal colon cancer autoantigen protein;
DE            Short=hCCCAP;
GN   Name=SDCCAG8; Synonyms=CCCAP, NPHP10; ORFNames=HSPC085;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035148; P:tube formation; ISS:UniProtKB.
//
ID   SDE2_HUMAN              Reviewed;         451 AA.
AC   Q6IQ49; A8K4P3; Q5TD36; Q6ZS26; Q8NAG7;
DE   RecName: Full=Protein SDE2 homolog;
GN   Name=SDE2; Synonyms=C1orf55;
//
ID   SDF1_HUMAN              Reviewed;          93 AA.
AC   P48061; B2R4G0; E7EVL0; H7BYN8; Q2L985; Q2L986; Q2L988; Q5IT36;
AC   Q6ICW0; Q9H554;
DE   RecName: Full=Stromal cell-derived factor 1;
DE            Short=SDF-1;
DE            Short=hSDF-1;
DE   AltName: Full=C-X-C motif chemokine 12;
DE   AltName: Full=Intercrine reduced in hepatomas;
DE            Short=IRH;
DE            Short=hIRH;
DE   AltName: Full=Pre-B cell growth-stimulating factor;
DE            Short=PBSF;
DE   Contains:
DE     RecName: Full=SDF-1-beta(3-72);
DE   Contains:
DE     RecName: Full=SDF-1-alpha(3-67);
DE   Flags: Precursor;
GN   Name=CXCL12; Synonyms=SDF1, SDF1A, SDF1B;
DR   GO; GO:0008009; F:chemokine activity; TAS:UniProtKB.
DR   GO; GO:0042379; F:chemokine receptor binding; IMP:UniProtKB.
DR   GO; GO:0045236; F:CXCR chemokine receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0001667; P:ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006935; P:chemotaxis; TAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IEA:Ensembl.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IDA:BHF-UCL.
DR   GO; GO:2000107; P:negative regulation of leukocyte apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; TAS:BHF-UCL.
DR   GO; GO:0033603; P:positive regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; TAS:ProtInc.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0022029; P:telencephalon cell migration; IEA:Ensembl.
//
ID   SDF2L_HUMAN             Reviewed;         221 AA.
AC   Q9HCN8; A2RUD3; Q9BRI5;
DE   RecName: Full=Stromal cell-derived factor 2-like protein 1;
DE            Short=SDF2-like protein 1;
DE   AltName: Full=PWP1-interacting protein 8;
DE   Flags: Precursor;
GN   Name=SDF2L1; ORFNames=UNQ1941/PRO4424;
//
ID   SDF2_HUMAN              Reviewed;         211 AA.
AC   Q99470; Q9BQ79;
DE   RecName: Full=Stromal cell-derived factor 2;
DE            Short=SDF-2;
DE   Flags: Precursor;
GN   Name=SDF2;
DR   GO; GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0035269; P:protein O-linked mannosylation; TAS:GOC.
//
ID   SDHA_HUMAN              Reviewed;         664 AA.
AC   P31040; A8K5J6; Q16395; Q9UMY5;
DE   RecName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial;
DE            EC=1.3.5.1;
DE   AltName: Full=Flavoprotein subunit of complex II;
DE            Short=Fp;
DE   Flags: Precursor;
GN   Name=SDHA; Synonyms=SDH2, SDHF;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006105; P:succinate metabolic process; IDA:UniProtKB.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:UniProtKB.
//
ID   SDHB_HUMAN              Reviewed;         280 AA.
AC   P21912; B2R545; Q9NQ12;
DE   RecName: Full=Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial;
DE            EC=1.3.5.1;
DE   AltName: Full=Iron-sulfur subunit of complex II;
DE            Short=Ip;
DE   Flags: Precursor;
GN   Name=SDHB; Synonyms=SDH, SDH1;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; ISS:UniProtKB.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; ISS:UniProtKB.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; ISS:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0048039; F:ubiquinone binding; ISS:UniProtKB.
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006105; P:succinate metabolic process; IEA:Ensembl.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   SDHF1_HUMAN             Reviewed;         115 AA.
AC   A6NFY7; B2RPM7;
DE   RecName: Full=Succinate dehydrogenase assembly factor 1, mitochondrial;
DE            Short=SDH assembly factor 1;
DE   AltName: Full=LYR motif-containing protein 8;
GN   Name=SDHAF1; Synonyms=LYRM8;
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; NAS:UniProtKB.
DR   GO; GO:0034553; P:mitochondrial respiratory chain complex II assembly; IMP:UniProtKB.
//
ID   SDHF2_HUMAN             Reviewed;         166 AA.
AC   Q9NX18;
DE   RecName: Full=Succinate dehydrogenase assembly factor 2, mitochondrial;
DE            Short=SDH assembly factor 2;
DE   AltName: Full=Succinate dehydrogenase subunit 5, mitochondrial;
DE            Short=hSDH5;
DE   Flags: Precursor;
GN   Name=SDHAF2; Synonyms=C11orf79, PGL2, SDH5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006121; P:mitochondrial electron transport, succinate to ubiquinone; IMP:UniProtKB.
DR   GO; GO:0018293; P:protein-FAD linkage; IMP:UniProtKB.
//
ID   SDHL_HUMAN              Reviewed;         328 AA.
AC   P20132; A8K9P5;
DE   RecName: Full=L-serine dehydratase/L-threonine deaminase;
DE            Short=SDH;
DE            EC=4.3.1.17;
DE   AltName: Full=L-serine deaminase;
DE   AltName: Full=L-threonine dehydratase;
DE            Short=TDH;
DE            EC=4.3.1.19;
GN   Name=SDS; Synonyms=SDH;
DR   GO; GO:0003941; F:L-serine ammonia-lyase activity; IDA:UniProtKB.
DR   GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0033590; P:response to cobalamin; IEA:Ensembl.
//
ID   SDIM1_HUMAN             Reviewed;         146 AA.
AC   Q6ZPB5;
DE   RecName: Full=Stress-responsive DNAJB4-interacting membrane protein 1;
DE   Flags: Precursor;
GN   Name=SDIM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0033554; P:cellular response to stress; IEP:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IDA:UniProtKB.
//
ID   SDK1_HUMAN              Reviewed;        2213 AA.
AC   Q7Z5N4; Q8TEN9; Q8TEP5; Q96N44;
DE   RecName: Full=Protein sidekick-1;
DE   Flags: Precursor;
GN   Name=SDK1;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SDK2_HUMAN              Reviewed;        2172 AA.
AC   Q58EX2; A6NMR8; C9JA57; Q86VY3; Q9NTD2; Q9NVB3; Q9P214;
DE   RecName: Full=Protein sidekick-2;
DE   Flags: Precursor;
GN   Name=SDK2; Synonyms=KIAA1514;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SDOS_HUMAN              Reviewed;         211 AA.
AC   Q9BRJ7; Q8NAI2;
DE   RecName: Full=Protein syndesmos;
DE   AltName: Full=NUDT16-like protein 1;
GN   Name=NUDT16L1; Synonyms=SDOS;
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030515; F:snoRNA binding; IDA:UniProtKB.
//
ID   SDPR_HUMAN              Reviewed;         425 AA.
AC   O95810;
DE   RecName: Full=Serum deprivation-response protein;
DE   AltName: Full=Cavin-2;
DE   AltName: Full=PS-p68;
DE   AltName: Full=Phosphatidylserine-binding protein;
GN   Name=SDPR;
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SDS3_HUMAN              Reviewed;         328 AA.
AC   Q9H7L9; Q4KMQ5; Q8N6H0; Q9H8D2;
DE   RecName: Full=Sin3 histone deacetylase corepressor complex component SDS3;
DE   AltName: Full=45 kDa Sin3-associated polypeptide;
DE   AltName: Full=Suppressor of defective silencing 3 protein homolog;
GN   Name=SUDS3; Synonyms=SAP45, SDS3;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0016575; P:histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SDSL_HUMAN              Reviewed;         329 AA.
AC   Q96GA7;
DE   RecName: Full=Serine dehydratase-like;
DE   AltName: Full=L-serine deaminase;
DE   AltName: Full=L-serine dehydratase/L-threonine deaminase;
DE   AltName: Full=L-threonine dehydratase;
DE            Short=TDH;
DE            EC=4.3.1.19;
DE   AltName: Full=Serine dehydratase 2;
DE            Short=SDH 2;
DE            EC=4.3.1.17;
GN   Name=SDSL;
DR   GO; GO:0003941; F:L-serine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
//
ID   SE1L1_HUMAN             Reviewed;         794 AA.
AC   Q9UBV2; Q6UWT6; Q9P1T9; Q9UHK7;
DE   RecName: Full=Protein sel-1 homolog 1;
DE   AltName: Full=Suppressor of lin-12-like protein 1;
DE            Short=Sel-1L;
DE   Flags: Precursor;
GN   Name=SEL1L; Synonyms=TSA305; ORFNames=UNQ128/PRO1063;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
//
ID   SE1L2_HUMAN             Reviewed;         688 AA.
AC   Q5TEA6; B4DXX5;
DE   RecName: Full=Protein sel-1 homolog 2;
DE   AltName: Full=Suppressor of lin-12-like protein 2;
DE            Short=Sel-1L2;
DE   Flags: Precursor;
GN   Name=SEL1L2; Synonyms=C20orf50;
//
ID   SE1L3_HUMAN             Reviewed;        1132 AA.
AC   Q68CR1; A0PJH6; A8K0X2; O94847; Q6P999; Q96G59;
DE   RecName: Full=Protein sel-1 homolog 3;
DE   AltName: Full=Suppressor of lin-12-like protein 3;
DE            Short=Sel-1L3;
GN   Name=SEL1L3; Synonyms=KIAA0746;
//
ID   SE6L1_HUMAN             Reviewed;        1024 AA.
AC   Q9BYH1; A0AUW7; B0QYG4; B0QYG5; B7ZLJ6; G8JLP3; O95917; Q5THY5;
AC   Q6IBZ4; Q6UXD4; Q9NUI3; Q9NUI4; Q9NUI5; Q9Y2E1; Q9Y3J6;
DE   RecName: Full=Seizure 6-like protein;
DE   Flags: Precursor;
GN   Name=SEZ6L; Synonyms=KIAA0927; ORFNames=UNQ2542/PRO6094;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0060074; P:synapse maturation; IEA:Ensembl.
//
ID   SE6L2_HUMAN             Reviewed;         910 AA.
AC   Q6UXD5; B7Z1N0; F5H293; H7BXQ6; Q9BW82; Q9UJ45; Q9UJ46; Q9UJ47;
DE   RecName: Full=Seizure 6-like protein 2;
DE   Flags: Precursor;
GN   Name=SEZ6L2; Synonyms=PSK; ORFNames=UNQ1903/PRO4349;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0060074; P:synapse maturation; IEA:Ensembl.
//
ID   SEAS1_HUMAN             Reviewed;         156 AA.
AC   Q5TG53;
DE   RecName: Full=Putative uncharacterized protein SERTAD4-AS1;
DE   AltName: Full=SERTAD4 antisense RNA 1;
DE   AltName: Full=SERTAD4 antisense gene protein 1;
GN   Name=SERTAD4-AS1; Synonyms=C1orf133;
//
ID   SEBOX_HUMAN             Reviewed;         216 AA.
AC   Q9HB31;
DE   RecName: Full=Homeobox protein SEBOX;
DE   AltName: Full=Homeobox OG-9;
DE   AltName: Full=Skin-, embryo-, brain- and oocyte-specific homeobox;
GN   Name=SEBOX; Synonyms=OG9X;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SEBP2_HUMAN             Reviewed;         854 AA.
AC   Q96T21; Q5HYY1; Q8IYC0; Q9H0A1;
DE   RecName: Full=Selenocysteine insertion sequence-binding protein 2;
DE            Short=SECIS-binding protein 2;
GN   Name=SECISBP2; Synonyms=SBP2;
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:Ensembl.
DR   GO; GO:0035368; F:selenocysteine insertion sequence binding; IEA:Ensembl.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
//
ID   SEC13_HUMAN             Reviewed;         322 AA.
AC   P55735; A8MV37; B4DXJ1; Q5BJF0; Q9BRM6; Q9BUG7;
DE   RecName: Full=Protein SEC13 homolog;
DE   AltName: Full=SEC13-like protein 1;
DE   AltName: Full=SEC13-related protein;
GN   Name=SEC13; Synonyms=D3S1231E, SEC13L1, SEC13R;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:Reactome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   SEC20_HUMAN             Reviewed;         228 AA.
AC   Q12981; D3DQM3; D3DQM4; D3DQM5; D3DQM6; O75622; O75623; O75624;
AC   Q6K044; Q96FG4;
DE   RecName: Full=Vesicle transport protein SEC20;
DE   AltName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 1;
DE   AltName: Full=Transformation-related gene 8 protein;
DE            Short=TRG-8;
GN   Name=BNIP1; Synonyms=NIP1, SEC20L; ORFNames=TRG8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:FlyBase.
DR   GO; GO:0006915; P:apoptotic process; IPI:MGI.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0016320; P:endoplasmic reticulum membrane fusion; IMP:HGNC.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IMP:HGNC.
DR   GO; GO:0097194; P:execution phase of apoptosis; IC:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   SEC62_HUMAN             Reviewed;         399 AA.
AC   Q99442; D3DNQ0; O00682; O00729;
DE   RecName: Full=Translocation protein SEC62;
DE   AltName: Full=Translocation protein 1;
DE            Short=TP-1;
DE            Short=hTP-1;
GN   Name=SEC62; Synonyms=TLOC1;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0006620; P:posttranslational protein targeting to membrane; IMP:MGI.
//
ID   SEC63_HUMAN             Reviewed;         760 AA.
AC   Q9UGP8; O95380; Q5THN4; Q86VS9; Q8IWL0; Q9NTE0;
DE   RecName: Full=Translocation protein SEC63 homolog;
GN   Name=SEC63; Synonyms=SEC63L;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:Ensembl.
DR   GO; GO:0006620; P:posttranslational protein targeting to membrane; IMP:MGI.
DR   GO; GO:0031204; P:posttranslational protein targeting to membrane, translocation; IEA:InterPro.
DR   GO; GO:0006612; P:protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0072001; P:renal system development; IEA:Ensembl.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IMP:MGI.
//
ID   SECR_HUMAN              Reviewed;         121 AA.
AC   P09683;
DE   RecName: Full=Secretin;
DE   Flags: Precursor;
GN   Name=SCT;
DR   GO; GO:0005179; F:hormone activity; NAS:UniProtKB.
DR   GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0030157; P:pancreatic juice secretion; NAS:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   SEGN_HUMAN              Reviewed;         276 AA.
AC   O76038; A8K0B2; Q5VV44; Q96QV7; Q9UJF6;
DE   RecName: Full=Secretagogin;
GN   Name=SCGN; Synonyms=SECRET;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
//
ID   SEH1_HUMAN              Reviewed;         360 AA.
AC   Q96EE3; A8K5B1; Q8NFU6; Q96MH3; Q9C069;
DE   RecName: Full=Nucleoporin SEH1;
DE   AltName: Full=Nup107-160 subcomplex subunit SEH1;
DE   AltName: Full=SEC13-like protein;
GN   Name=SEH1L; Synonyms=SEC13L, SEH1;
DR   GO; GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006999; P:nuclear pore organization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   SEHL2_HUMAN             Reviewed;         314 AA.
AC   Q9H4I8; B1AHE9; B1AHF0; Q0VDJ1; Q5H973; Q9BR29; Q9BR30; Q9Y3I9;
DE   RecName: Full=Serine hydrolase-like protein 2;
DE            EC=3.1.-.-;
GN   Name=SERHL2; Synonyms=SERHL;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   SELB_HUMAN              Reviewed;         596 AA.
AC   P57772;
DE   RecName: Full=Selenocysteine-specific elongation factor;
DE   AltName: Full=Elongation factor sec;
DE   AltName: Full=Eukaryotic elongation factor, selenocysteine-tRNA-specific;
GN   Name=EEFSEC; Synonyms=SELB;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:Ensembl.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:Ensembl.
DR   GO; GO:0035368; F:selenocysteine insertion sequence binding; IEA:Ensembl.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:Ensembl.
DR   GO; GO:0000049; F:tRNA binding; IEA:Ensembl.
DR   GO; GO:0001514; P:selenocysteine incorporation; IEA:Ensembl.
//
ID   SELH_HUMAN              Reviewed;         122 AA.
AC   Q8IZQ5; Q8N672;
DE   RecName: Full=Selenoprotein H;
DE            Short=SelH;
GN   Name=SELH; Synonyms=C11orf31;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   SELK_HUMAN              Reviewed;          94 AA.
AC   Q9Y6D0; Q8IZQ3; Q9P085;
DE   RecName: Full=Selenoprotein K;
DE            Short=SelK;
GN   Name=SELK; ORFNames=HSPC030, HSPC297;
DR   GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:UniProtKB.
DR   GO; GO:2000406; P:positive regulation of T cell migration; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045728; P:respiratory burst after phagocytosis; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
//
ID   SELM_HUMAN              Reviewed;         145 AA.
AC   Q8WWX9; A8MPZ2;
DE   RecName: Full=Selenoprotein M;
DE            Short=SelM;
DE   Flags: Precursor;
GN   Name=SELM; Synonyms=SEPM;
//
ID   SELN_HUMAN              Reviewed;         590 AA.
AC   Q9NZV5; A6NJG8; A8MQ64; Q6PI70; Q969F6; Q9NUI6;
DE   RecName: Full=Selenoprotein N;
DE            Short=SelN;
DE   Flags: Precursor;
GN   Name=SEPN1; Synonyms=SELN;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SELO_HUMAN              Reviewed;         669 AA.
AC   Q9BVL4; Q2TAL2; Q5JZ81; Q8WUI0;
DE   RecName: Full=Selenoprotein O;
DE            Short=SelO;
GN   Name=SELO;
//
ID   SELPL_HUMAN             Reviewed;         412 AA.
AC   Q14242; A8K2Y0; B4DQC3; B7Z5C7; J3KMX6; Q12775; Q6GTW7; Q8N7J7;
DE   RecName: Full=P-selectin glycoprotein ligand 1;
DE            Short=PSGL-1;
DE   AltName: Full=Selectin P ligand;
DE   AltName: CD_antigen=CD162;
DE   Flags: Precursor;
GN   Name=SELPLG;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; NAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0071354; P:cellular response to interleukin-6; IDA:MGI.
DR   GO; GO:0050902; P:leukocyte adhesive activation; ISS:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IEA:Ensembl.
//
ID   SELS_HUMAN              Reviewed;         189 AA.
AC   Q9BQE4; Q3B771; Q9P0I6;
DE   RecName: Full=Selenoprotein S;
DE            Short=SelS;
DE   AltName: Full=VCP-interacting membrane protein;
GN   Name=VIMP; Synonyms=SELS; ORFNames=AD-015, SBBI8;
DR   GO; GO:0016209; F:antioxidant activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; TAS:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0006983; P:ER overload response; IDA:BHF-UCL.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; TAS:UniProtKB.
DR   GO; GO:0002865; P:negative regulation of acute inflammatory response to antigenic stimulus; IMP:BHF-UCL.
DR   GO; GO:0046325; P:negative regulation of glucose import; TAS:BHF-UCL.
DR   GO; GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.
DR   GO; GO:1902236; P:negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:BHF-UCL.
DR   GO; GO:2000110; P:negative regulation of macrophage apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0051771; P:negative regulation of nitric-oxide synthase biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0006111; P:regulation of gluconeogenesis; TAS:BHF-UCL.
DR   GO; GO:0080164; P:regulation of nitric oxide metabolic process; IMP:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IEP:UniProtKB.
DR   GO; GO:0051775; P:response to redox state; IDA:UniProtKB.
DR   GO; GO:0030970; P:retrograde protein transport, ER to cytosol; IDA:UniProtKB.
//
ID   SELT_HUMAN              Reviewed;         195 AA.
AC   P62341; O95904; Q8IY80; Q9CZ45; Q9NZJ3;
DE   RecName: Full=Selenoprotein T;
DE            Short=SelT;
DE   Flags: Precursor;
GN   Name=SELT; ORFNames=UNQ150/PRO176;
DR   GO; GO:0008430; F:selenium binding; NAS:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0001514; P:selenocysteine incorporation; NAS:UniProtKB.
//
ID   SELV_HUMAN              Reviewed;         346 AA.
AC   P59797; Q17RG5;
DE   RecName: Full=Selenoprotein V;
DE            Short=SelV;
GN   Name=SELV;
DR   GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   SELW_HUMAN              Reviewed;          87 AA.
AC   P63302; A8MRR7; O15532; O19096; Q86TI9; Q96KM5;
DE   RecName: Full=Selenoprotein W;
DE            Short=SelW;
GN   Name=SEPW1; Synonyms=SELW;
DR   GO; GO:0016209; F:antioxidant activity; IEA:UniProtKB-KW.
DR   GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   SEM3A_HUMAN             Reviewed;         771 AA.
AC   Q14563;
DE   RecName: Full=Semaphorin-3A;
DE   AltName: Full=Semaphorin III;
DE            Short=Sema III;
DE   Flags: Precursor;
GN   Name=SEMA3A; Synonyms=SEMAD;
DR   GO; GO:0045499; F:chemorepellent activity; TAS:BHF-UCL.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:Ensembl.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:BHF-UCL.
DR   GO; GO:0007413; P:axonal fasciculation; IEA:Ensembl.
DR   GO; GO:0060385; P:axonogenesis involved in innervation; ISS:BHF-UCL.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0060666; P:dichotomous subdivision of terminal units involved in salivary gland branching; IEA:Ensembl.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; ISS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; ISS:BHF-UCL.
DR   GO; GO:0021772; P:olfactory bulb development; IMP:UniProtKB.
DR   GO; GO:2001224; P:positive regulation of neuron migration; IEA:Ensembl.
DR   GO; GO:0048841; P:regulation of axon extension involved in axon guidance; IDA:UniProtKB.
DR   GO; GO:0002027; P:regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; TAS:BHF-UCL.
DR   GO; GO:1902285; P:semaphorin-plexin signaling pathway involved in neuron projection guidance; ISS:BHF-UCL.
DR   GO; GO:0048880; P:sensory system development; TAS:BHF-UCL.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:BHF-UCL.
DR   GO; GO:0048485; P:sympathetic nervous system development; TAS:BHF-UCL.
DR   GO; GO:0097490; P:sympathetic neuron projection extension; ISS:BHF-UCL.
DR   GO; GO:0097491; P:sympathetic neuron projection guidance; ISS:BHF-UCL.
//
ID   SEM3B_HUMAN             Reviewed;         749 AA.
AC   Q13214; Q6GU46; Q8TB71; Q8TDV7; Q93018; Q96GX0;
DE   RecName: Full=Semaphorin-3B;
DE   AltName: Full=Sema A(V);
DE   AltName: Full=Semaphorin-V;
DE            Short=Sema V;
DE   Flags: Precursor;
GN   Name=SEMA3B; Synonyms=SEMA5, SEMAA;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
//
ID   SEM3C_HUMAN             Reviewed;         751 AA.
AC   Q99985;
DE   RecName: Full=Semaphorin-3C;
DE   AltName: Full=Semaphorin-E;
DE            Short=Sema E;
DE   Flags: Precursor;
GN   Name=SEMA3C; Synonyms=SEMAE;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; IEA:Ensembl.
DR   GO; GO:0060666; P:dichotomous subdivision of terminal units involved in salivary gland branching; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0003350; P:pulmonary myocardium development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; TAS:ProtInc.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   SEM3D_HUMAN             Reviewed;         777 AA.
AC   O95025; A6NK46; Q6UW77; Q8NCQ1;
DE   RecName: Full=Semaphorin-3D;
DE   Flags: Precursor;
GN   Name=SEMA3D; ORFNames=UNQ760/PRO1491;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   SEM3E_HUMAN             Reviewed;         775 AA.
AC   O15041; B4E1P1; Q75M94; Q75M97;
DE   RecName: Full=Semaphorin-3E;
DE   Flags: Precursor;
GN   Name=SEMA3E; Synonyms=KIAA0331, SEMAH;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; ISS:UniProtKB.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:UniProtKB.
DR   GO; GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; ISS:UniProtKB.
//
ID   SEM3F_HUMAN             Reviewed;         785 AA.
AC   Q13275; C9JQ85; Q13274; Q13372; Q15704; Q6GTR4;
DE   RecName: Full=Semaphorin-3F;
DE   AltName: Full=Sema III/F;
DE   AltName: Full=Semaphorin IV;
DE            Short=Sema IV;
DE   Flags: Precursor;
GN   Name=SEMA3F;
DR   GO; GO:0045499; F:chemorepellent activity; IDA:MGI.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; IDA:MGI.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; ISS:BHF-UCL.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:1902285; P:semaphorin-plexin signaling pathway involved in neuron projection guidance; ISS:BHF-UCL.
DR   GO; GO:0061549; P:sympathetic ganglion development; ISS:BHF-UCL.
DR   GO; GO:0097490; P:sympathetic neuron projection extension; ISS:BHF-UCL.
DR   GO; GO:0097491; P:sympathetic neuron projection guidance; ISS:BHF-UCL.
//
ID   SEM3G_HUMAN             Reviewed;         782 AA.
AC   Q9NS98; Q7L9D9; Q9H7Q3;
DE   RecName: Full=Semaphorin-3G;
DE   AltName: Full=Semaphorin sem2;
DE   Flags: Precursor;
GN   Name=SEMA3G;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
//
ID   SEM4A_HUMAN             Reviewed;         761 AA.
AC   Q9H3S1; B2RDH8; B3KR76; Q5TCI5; Q5TCJ6; Q8WUA9;
DE   RecName: Full=Semaphorin-4A;
DE   AltName: Full=Semaphorin-B;
DE            Short=Sema B;
DE   Flags: Precursor;
GN   Name=SEMA4A; Synonyms=SEMAB, SEMB; ORFNames=UNQ783/PRO1317;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0010594; P:regulation of endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; IEA:Ensembl.
DR   GO; GO:0045063; P:T-helper 1 cell differentiation; IEA:Ensembl.
//
ID   SEM4B_HUMAN             Reviewed;         832 AA.
AC   Q9NPR2; Q6UXE3; Q8WVP9; Q96FK5; Q9C0B8; Q9H691; Q9NPM8; Q9NPN0;
DE   RecName: Full=Semaphorin-4B;
DE   Flags: Precursor;
GN   Name=SEMA4B; Synonyms=KIAA1745, SEMAC; ORFNames=UNQ749/PRO1480;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   SEM4C_HUMAN             Reviewed;         833 AA.
AC   Q9C0C4; Q32MJ3; Q7Z5X0;
DE   RecName: Full=Semaphorin-4C;
DE   Flags: Precursor;
GN   Name=SEMA4C; Synonyms=KIAA1739, SEMAI; ORFNames=UNQ5855/PRO34487;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0021535; P:cell migration in hindbrain; ISS:UniProtKB.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; ISS:UniProtKB.
//
ID   SEM4D_HUMAN             Reviewed;         862 AA.
AC   Q92854; B2RPM6; Q7Z5S4; Q8N8B0;
DE   RecName: Full=Semaphorin-4D;
DE   AltName: Full=A8;
DE   AltName: Full=BB18;
DE   AltName: Full=GR3;
DE   AltName: CD_antigen=CD100;
DE   Flags: Precursor;
GN   Name=SEMA4D; Synonyms=C9orf164, CD100, SEMAJ;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:HGNC.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0030215; F:semaphorin receptor binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0070486; P:leukocyte aggregation; IMP:UniProtKB.
DR   GO; GO:0010693; P:negative regulation of alkaline phosphatase activity; IMP:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; ISS:BHF-UCL.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0043931; P:ossification involved in bone maturation; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0048672; P:positive regulation of collateral sprouting; IMP:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IMP:UniProtKB.
DR   GO; GO:0031344; P:regulation of cell projection organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; IDA:UniProtKB.
DR   GO; GO:1900220; P:semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis; ISS:BHF-UCL.
//
ID   SEM4F_HUMAN             Reviewed;         770 AA.
AC   O95754; Q542Y7; Q9NS35;
DE   RecName: Full=Semaphorin-4F;
DE   AltName: Full=Semaphorin-M;
DE            Short=Sema M;
DE   AltName: Full=Semaphorin-W;
DE            Short=Sema W;
DE   Flags: Precursor;
GN   Name=SEMA4F; Synonyms=SEMAM, SEMAW;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0030517; P:negative regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
//
ID   SEM4G_HUMAN             Reviewed;         838 AA.
AC   Q9NTN9; A1A5C6; A6NJY8; Q58EY1; Q9HCF3;
DE   RecName: Full=Semaphorin-4G;
DE   Flags: Precursor;
GN   Name=SEMA4G; Synonyms=KIAA1619;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   SEM5A_HUMAN             Reviewed;        1074 AA.
AC   Q13591; D3DTC6; O60408; Q1RLL9;
DE   RecName: Full=Semaphorin-5A;
DE   AltName: Full=Semaphorin-F;
DE            Short=Sema F;
DE   Flags: Precursor;
GN   Name=SEMA5A; Synonyms=SEMAF;
DR   GO; GO:0008046; F:axon guidance receptor activity; IEA:Ensembl.
DR   GO; GO:0035373; F:chondroitin sulfate proteoglycan binding; ISS:UniProtKB.
DR   GO; GO:0043395; F:heparan sulfate proteoglycan binding; ISS:UniProtKB.
DR   GO; GO:0030215; F:semaphorin receptor binding; ISS:UniProtKB.
DR   GO; GO:0045545; F:syndecan binding; ISS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007413; P:axonal fasciculation; ISS:UniProtKB.
DR   GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0021536; P:diencephalon development; ISS:UniProtKB.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; ISS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0050918; P:positive chemotaxis; ISS:UniProtKB.
DR   GO; GO:0030836; P:positive regulation of actin filament depolymerization; ISS:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; ISS:UniProtKB.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; ISS:UniProtKB.
DR   GO; GO:2001028; P:positive regulation of endothelial cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:1990256; P:signal clustering; ISS:UniProtKB.
//
ID   SEM5B_HUMAN             Reviewed;        1151 AA.
AC   Q9P283; A8K5U2; B7Z393; F8W9U8; Q6DD89; Q6UY12; Q9NW17;
DE   RecName: Full=Semaphorin-5B;
GN   Name=SEMA5B; Synonyms=KIAA1445, SEMAG; ORFNames=UNQ5867/PRO34001;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   SEM6A_HUMAN             Reviewed;        1030 AA.
AC   Q9H2E6; Q9P2H9;
DE   RecName: Full=Semaphorin-6A;
DE   AltName: Full=Semaphorin VIA;
DE            Short=Sema VIA;
DE   AltName: Full=Semaphorin-6A-1;
DE            Short=SEMA6A-1;
DE   Flags: Precursor;
GN   Name=SEMA6A; Synonyms=KIAA1368, SEMAQ;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; NAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; NAS:UniProtKB.
DR   GO; GO:2001224; P:positive regulation of neuron migration; IEA:Ensembl.
DR   GO; GO:0071526; P:semaphorin-plexin signaling pathway; IEA:Ensembl.
//
ID   SEM6B_HUMAN             Reviewed;         888 AA.
AC   Q9H3T3; A5PKU4; F6IB19; Q9NRK9;
DE   RecName: Full=Semaphorin-6B;
DE   AltName: Full=Semaphorin-Z;
DE            Short=Sema Z;
DE   Flags: Precursor;
GN   Name=SEMA6B; Synonyms=SEMAN, SEMAZ; ORFNames=UNQ1907/PRO4353;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   SEM6C_HUMAN             Reviewed;         930 AA.
AC   Q9H3T2; D3DV15; Q5JR71; Q5JR72; Q5JR73; Q8WXT8; Q8WXT9; Q8WXU0;
AC   Q96JF8;
DE   RecName: Full=Semaphorin-6C;
DE   AltName: Full=Semaphorin-Y;
DE            Short=Sema Y;
DE   Flags: Precursor;
GN   Name=SEMA6C; Synonyms=KIAA1869, SEMAY;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
//
ID   SEM6D_HUMAN             Reviewed;        1073 AA.
AC   Q8NFY4; A6NF10; A6NM95; A6NNK1; A7E2A0; Q8NFY3; Q8NFY5; Q8NFY6;
AC   Q8NFY7; Q9P249;
DE   RecName: Full=Semaphorin-6D;
DE   Flags: Precursor;
GN   Name=SEMA6D; Synonyms=KIAA1479;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
//
ID   SEM7A_HUMAN             Reviewed;         666 AA.
AC   O75326; B4DDP7; F5H1S0; Q1XE81; Q1XE82; Q1XE83; Q1XE84; Q3MIY5;
DE   RecName: Full=Semaphorin-7A;
DE   AltName: Full=CDw108;
DE   AltName: Full=JMH blood group antigen;
DE   AltName: Full=John-Milton-Hargen human blood group Ag;
DE   AltName: Full=Semaphorin-K1;
DE            Short=Sema K1;
DE   AltName: Full=Semaphorin-L;
DE            Short=Sema L;
DE   AltName: CD_antigen=CD108;
DE   Flags: Precursor;
GN   Name=SEMA7A; Synonyms=CD108, SEMAL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045773; P:positive regulation of axon extension; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; ISS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
//
ID   SEMG1_HUMAN             Reviewed;         462 AA.
AC   P04279; Q53ZV0; Q53ZV1; Q53ZV2; Q6X4I9; Q6Y809; Q6Y822; Q6Y823;
AC   Q86U64; Q96QM3;
DE   RecName: Full=Semenogelin-1;
DE   AltName: Full=Semenogelin I;
DE            Short=SGI;
DE   Contains:
DE     RecName: Full=Alpha-inhibin-92;
DE   Contains:
DE     RecName: Full=Alpha-inhibin-31;
DE   Contains:
DE     RecName: Full=Seminal basic protein;
DE   Flags: Precursor;
GN   Name=SEMG1; Synonyms=SEMG;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0007320; P:insemination; TAS:ProtInc.
//
ID   SEMG2_HUMAN             Reviewed;         582 AA.
AC   Q02383; Q53ZU2; Q6X2M5; Q6X2M6;
DE   RecName: Full=Semenogelin-2;
DE   AltName: Full=Semenogelin II;
DE            Short=SGII;
DE   Flags: Precursor;
GN   Name=SEMG2;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019953; P:sexual reproduction; IEA:InterPro.
//
ID   SEN15_HUMAN             Reviewed;         171 AA.
AC   Q8WW01; B4DKP0; Q9BZQ5;
DE   RecName: Full=tRNA-splicing endonuclease subunit Sen15;
DE   AltName: Full=SEN15 homolog;
DE            Short=HsSEN15;
DE   AltName: Full=tRNA-intron endonuclease Sen15;
GN   Name=TSEN15; Synonyms=C1orf19, SEN15;
DR   GO; GO:0000213; F:tRNA-intron endonuclease activity; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:InterPro.
//
ID   SEN2_HUMAN              Reviewed;         465 AA.
AC   Q8NCE0; B7Z6K1; C9IZI7; G5E9Q3; Q8WTW7; Q9BPU7;
DE   RecName: Full=tRNA-splicing endonuclease subunit Sen2;
DE            EC=4.6.1.16;
DE   AltName: Full=tRNA-intron endonuclease Sen2;
DE            Short=HsSen2;
GN   Name=TSEN2; Synonyms=SEN2;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000213; F:tRNA-intron endonuclease activity; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IDA:UniProtKB.
//
ID   SEN34_HUMAN             Reviewed;         310 AA.
AC   Q9BSV6; A6NNB1; B0V3J1; Q9BVT1; Q9H6H5;
DE   RecName: Full=tRNA-splicing endonuclease subunit Sen34;
DE            EC=4.6.1.16;
DE   AltName: Full=Leukocyte receptor cluster member 5;
DE   AltName: Full=tRNA-intron endonuclease Sen34;
DE            Short=HsSen34;
GN   Name=TSEN34; Synonyms=LENG5, SEN34;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000213; F:tRNA-intron endonuclease activity; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000379; P:tRNA-type intron splice site recognition and cleavage; IEA:InterPro.
//
ID   SEN54_HUMAN             Reviewed;         526 AA.
AC   Q7Z6J9; Q86WV3; Q86XE4; Q8N9H2;
DE   RecName: Full=tRNA-splicing endonuclease subunit Sen54;
DE   AltName: Full=SEN54 homolog;
DE            Short=HsSEN54;
DE   AltName: Full=tRNA-intron endonuclease Sen54;
GN   Name=TSEN54; Synonyms=SEN54;
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IDA:UniProtKB.
//
ID   SENP2_HUMAN             Reviewed;         589 AA.
AC   Q9HC62; Q8IW97; Q96SR2; Q9P2L5;
DE   RecName: Full=Sentrin-specific protease 2;
DE            EC=3.4.22.68;
DE   AltName: Full=Axam2;
DE   AltName: Full=SMT3-specific isopeptidase 2;
DE            Short=Smt3ip2;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP2;
GN   Name=SENP2; Synonyms=KIAA1331;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016929; F:SUMO-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0060711; P:labyrinthine layer development; IEA:Ensembl.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0035562; P:negative regulation of chromatin binding; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016926; P:protein desumoylation; ISS:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032875; P:regulation of DNA endoreduplication; IEA:Ensembl.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEA:Ensembl.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   SENP1_HUMAN             Reviewed;         644 AA.
AC   Q9P0U3; A8K7P5; Q86XC8;
DE   RecName: Full=Sentrin-specific protease 1;
DE            EC=3.4.22.68;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP1;
GN   Name=SENP1;
DR   GO; GO:0004175; F:endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016929; F:SUMO-specific protease activity; ISS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016926; P:protein desumoylation; ISS:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0010724; P:regulation of definitive erythrocyte differentiation; IEA:Ensembl.
//
ID   SENP3_HUMAN             Reviewed;         574 AA.
AC   Q9H4L4; Q66K15; Q86VS7; Q96PS4; Q9Y3W9;
DE   RecName: Full=Sentrin-specific protease 3;
DE            EC=3.4.22.68;
DE   AltName: Full=SUMO-1-specific protease 3;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP3;
GN   Name=SENP3; Synonyms=SSP3, SUSP3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IEA:Ensembl.
//
ID   SENP5_HUMAN             Reviewed;         755 AA.
AC   Q96HI0; Q96SA5;
DE   RecName: Full=Sentrin-specific protease 5;
DE            EC=3.4.22.68;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP5;
GN   Name=SENP5; ORFNames=FKSG45;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016925; P:protein sumoylation; TAS:Reactome.
//
ID   SENP6_HUMAN             Reviewed;        1112 AA.
AC   Q9GZR1; A6NNY9; O94891; Q5VUL3; Q5VUL4; Q8TBY4; Q9UJV5;
DE   RecName: Full=Sentrin-specific protease 6;
DE            EC=3.4.22.68;
DE   AltName: Full=SUMO-1-specific protease 1;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP6;
GN   Name=SENP6; Synonyms=KIAA0797, SSP1, SUSP1; ORFNames=FKSG6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016929; F:SUMO-specific protease activity; IMP:UniProtKB.
DR   GO; GO:0016926; P:protein desumoylation; IMP:UniProtKB.
DR   GO; GO:0070646; P:protein modification by small protein removal; IDA:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0090234; P:regulation of kinetochore assembly; IMP:UniProtKB.
DR   GO; GO:0090169; P:regulation of spindle assembly; IMP:UniProtKB.
//
ID   SENP8_HUMAN             Reviewed;         212 AA.
AC   Q96LD8; Q96QA4;
DE   RecName: Full=Sentrin-specific protease 8;
DE            EC=3.4.22.68;
DE   AltName: Full=Deneddylase-1;
DE   AltName: Full=NEDD8-specific protease 1;
DE   AltName: Full=Protease, cysteine 2;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP8;
GN   Name=SENP8; Synonyms=DEN1, NEDP1, PRSC2; ORFNames=FKSG8;
DR   GuidetoPHARMACOLOGY; 2417; -.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
//
ID   SENP7_HUMAN             Reviewed;        1050 AA.
AC   Q9BQF6; A1L3A5; A8MW39; B7WNW8; Q7Z3F4; Q96PS5; Q9C0F6; Q9HBT5;
DE   RecName: Full=Sentrin-specific protease 7;
DE            EC=3.4.22.68;
DE   AltName: Full=SUMO-1-specific protease 2;
DE   AltName: Full=Sentrin/SUMO-specific protease SENP7;
GN   Name=SENP7; Synonyms=KIAA1707, SSP2, SUSP2;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SEP10_HUMAN             Reviewed;         454 AA.
AC   Q9P0V9; B3KRQ9; Q86VP5; Q9HAH6;
DE   RecName: Full=Septin-10;
GN   Name=SEPT10;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   SEP11_HUMAN             Reviewed;         429 AA.
AC   Q9NVA2; B7Z7Z6; E9KL32; Q4W5G1; Q7L4N1; Q96SP1; Q9UFY9;
DE   RecName: Full=Septin-11;
GN   Name=SEPT11;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0051291; P:protein heterooligomerization; IDA:UniProtKB.
//
ID   SEP12_HUMAN             Reviewed;         358 AA.
AC   Q8IYM1; Q0P6B0; Q1PBH0; Q96LL0;
DE   RecName: Full=Septin-12;
GN   Name=SEPT12;
DR   GO; GO:0019003; F:GDP binding; ISS:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   SEP14_HUMAN             Reviewed;         432 AA.
AC   Q6ZU15; A6NCC2; B4DXD6;
DE   RecName: Full=Septin-14;
GN   Name=SEPT14;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   SEP15_HUMAN             Reviewed;         162 AA.
AC   O60613; Q4GZG7; Q8WU00; Q9BS64; Q9GZW0; Q9NR01;
DE   RecName: Full=15 kDa selenoprotein;
DE   Flags: Precursor;
GN   Name=SEP15;
DR   GO; GO:0008430; F:selenium binding; IDA:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:UniProtKB.
//
ID   SEPP1_HUMAN             Reviewed;         381 AA.
AC   P49908; Q6PD59; Q6PI43; Q6PI87; Q6PJF9;
DE   RecName: Full=Selenoprotein P;
DE            Short=SeP;
DE   Flags: Precursor;
GN   Name=SEPP1; Synonyms=SELP;
DR   GO; GO:0008430; F:selenium binding; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0040007; P:growth; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0001887; P:selenium compound metabolic process; IEA:Ensembl.
DR   GO; GO:0019953; P:sexual reproduction; IEA:Ensembl.
//
ID   SEPR_HUMAN              Reviewed;         760 AA.
AC   Q12884; O00199; Q53TP5; Q86Z29; Q99998; Q9UID4;
DE   RecName: Full=Seprase;
DE            EC=3.4.21.-;
DE   AltName: Full=170 kDa melanoma membrane-bound gelatinase;
DE   AltName: Full=Fibroblast activation protein alpha;
DE   AltName: Full=Integral membrane serine protease;
GN   Name=FAP;
DR   GO; GO:0008239; F:dipeptidyl-peptidase activity; NAS:UniProtKB.
DR   GO; GO:0004175; F:endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IDA:MGI.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; NAS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0010716; P:negative regulation of extracellular matrix disassembly; IDA:UniProtKB.
DR   GO; GO:0051917; P:regulation of fibrinolysis; IC:BHF-UCL.
//
ID   SEPT1_HUMAN             Reviewed;         367 AA.
AC   Q8WYJ6; B4DVE6; Q658T1; Q8NEZ1; Q96EL4; Q9H285;
DE   RecName: Full=Septin-1;
DE   AltName: Full=LARP;
DE   AltName: Full=Peanut-like protein 3;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-24;
GN   Name=SEPT1; Synonyms=DIFF6, PNUTL3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   SEPT2_HUMAN             Reviewed;         361 AA.
AC   Q15019; B4DGE8; Q14132; Q53QU3; Q8IUK9; Q96CB0;
DE   RecName: Full=Septin-2;
DE   AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 5;
DE            Short=NEDD-5;
GN   Name=SEPT2; Synonyms=DIFF6, KIAA0158, NEDD5;
DR   GO; GO:0030234; F:enzyme regulator activity; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0002036; P:regulation of L-glutamate transport; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   SEPT3_HUMAN             Reviewed;         358 AA.
AC   Q9UH03; B1AHR0; Q2NKJ7; Q59GF7; Q6IBZ6; Q8N3P3; Q9HD35;
DE   RecName: Full=Neuronal-specific septin-3;
GN   Name=SEPT3; Synonyms=SEP3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
//
ID   SEPT5_HUMAN             Reviewed;         369 AA.
AC   Q99719; O15251; Q96MY5;
DE   RecName: Full=Septin-5;
DE   AltName: Full=Cell division control-related protein 1;
DE            Short=CDCrel-1;
DE   AltName: Full=Peanut-like protein 1;
GN   Name=SEPT5; Synonyms=PNUTL1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0000910; P:cytokinesis; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0017157; P:regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0016080; P:synaptic vesicle targeting; TAS:UniProtKB.
//
ID   SEPT6_HUMAN             Reviewed;         434 AA.
AC   Q14141; Q5JTK0; Q969W5; Q96A13; Q96GR1; Q96P86; Q96P87;
DE   RecName: Full=Septin-6;
GN   Name=SEPT6; Synonyms=KIAA0128, SEP2;
DR   GO; GO:0005525; F:GTP binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SEPT4_HUMAN             Reviewed;         478 AA.
AC   O43236; B2RD42; B3KSX9; B4DXC6; B4DXV5; Q6IAP3; Q9H315; Q9UM58;
DE   RecName: Full=Septin-4;
DE   AltName: Full=Apoptosis-related protein in the TGF-beta signaling pathway;
DE            Short=ARTS;
DE   AltName: Full=Bradeion beta;
DE   AltName: Full=Brain protein H5;
DE   AltName: Full=CE5B3 beta;
DE   AltName: Full=Cell division control-related protein 2;
DE            Short=hCDCREL-2;
DE   AltName: Full=Cerebral protein 7;
DE   AltName: Full=Peanut-like protein 2;
GN   Name=SEPT4; Synonyms=ARTS, PNUTL2, SEP4; ORFNames=hucep-7;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0000910; P:cytokinesis; TAS:ProtInc.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0048240; P:sperm capacitation; IEA:Ensembl.
DR   GO; GO:0030382; P:sperm mitochondrion organization; IEA:Ensembl.
//
ID   SEPT7_HUMAN             Reviewed;         437 AA.
AC   Q16181; Q52M76; Q6NX50;
DE   RecName: Full=Septin-7;
DE   AltName: Full=CDC10 protein homolog;
GN   Name=SEPT7; Synonyms=CDC10;
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0051291; P:protein heterooligomerization; IDA:UniProtKB.
DR   GO; GO:0016476; P:regulation of embryonic cell shape; ISS:UniProtKB.
//
ID   SEPT8_HUMAN             Reviewed;         483 AA.
AC   Q92599; A6NC65; A6NKP6; F6W7K9; Q8IX36; Q8IX37; Q9BVB3;
DE   RecName: Full=Septin-8;
GN   Name=SEPT8; Synonyms=KIAA0202;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:InterPro.
//
ID   SEPT9_HUMAN             Reviewed;         586 AA.
AC   Q9UHD8; A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; Q96QF3;
AC   Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9Y5W4;
DE   RecName: Full=Septin-9;
DE   AltName: Full=MLL septin-like fusion protein MSF-A;
DE            Short=MLL septin-like fusion protein;
DE   AltName: Full=Ovarian/Breast septin;
DE            Short=Ov/Br septin;
DE   AltName: Full=Septin D1;
GN   Name=SEPT9; Synonyms=KIAA0991, MSF;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0051291; P:protein heterooligomerization; IDA:UniProtKB.
//
ID   SERA_HUMAN              Reviewed;         533 AA.
AC   O43175; B2RD08; Q5SZU3; Q9BQ01;
DE   RecName: Full=D-3-phosphoglycerate dehydrogenase;
DE            Short=3-PGDH;
DE            EC=1.1.1.95;
GN   Name=PHGDH; Synonyms=PGDH3;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0070314; P:G1 to G0 transition; IEA:Ensembl.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:Ensembl.
DR   GO; GO:0021782; P:glial cell development; IEA:Ensembl.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:Ensembl.
DR   GO; GO:0006544; P:glycine metabolic process; IEA:Ensembl.
DR   GO; GO:0006564; P:L-serine biosynthetic process; TAS:Reactome.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0019530; P:taurine metabolic process; IEA:Ensembl.
DR   GO; GO:0006566; P:threonine metabolic process; IEA:Ensembl.
//
ID   SERB_HUMAN              Reviewed;         225 AA.
AC   P78330; B2RCR5; Q7Z3S5;
DE   RecName: Full=Phosphoserine phosphatase;
DE            Short=PSP;
DE            Short=PSPase;
DE            EC=3.1.3.3;
DE   AltName: Full=L-3-phosphoserine phosphatase;
DE   AltName: Full=O-phosphoserine phosphohydrolase;
GN   Name=PSPH;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004647; F:phosphoserine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0006564; P:L-serine biosynthetic process; IBA:RefGenome.
DR   GO; GO:0006563; P:L-serine metabolic process; IDA:UniProtKB.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SERC1_HUMAN             Reviewed;         453 AA.
AC   Q9NRX5; B3KY69; E1P565; O75655; Q7Z2F5; Q8TAG1; Q9NTH8; Q9ULG7;
DE   RecName: Full=Serine incorporator 1;
DE   AltName: Full=Tumor differentially expressed protein 1-like;
DE   AltName: Full=Tumor differentially expressed protein 2;
GN   Name=SERINC1; Synonyms=KIAA1253, TDE1L, TDE2; ORFNames=UNQ396/PRO732;
DR   GO; GO:0015194; F:L-serine transmembrane transporter activity; ISS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015825; P:L-serine transport; ISS:HGNC.
DR   GO; GO:0006658; P:phosphatidylserine metabolic process; ISS:HGNC.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0051347; P:positive regulation of transferase activity; ISS:HGNC.
DR   GO; GO:0006665; P:sphingolipid metabolic process; ISS:HGNC.
//
ID   SERC2_HUMAN             Reviewed;         455 AA.
AC   Q96SA4; A0AVB4; B4DJK5; B7Z567; B7ZAP2; E7EUZ9; Q86Y23;
DE   RecName: Full=Serine incorporator 2;
DE   AltName: Full=Tumor differentially expressed protein 2-like;
GN   Name=SERINC2; Synonyms=TDE2L; ORFNames=FKSG84, UNQ263/PRO300;
DR   GO; GO:0006658; P:phosphatidylserine metabolic process; IEA:Ensembl.
DR   GO; GO:0051347; P:positive regulation of transferase activity; IEA:Ensembl.
//
ID   SERC3_HUMAN             Reviewed;         473 AA.
AC   Q13530; O43717; Q9BR33;
DE   RecName: Full=Serine incorporator 3;
DE   AltName: Full=Tumor differentially expressed protein 1;
GN   Name=SERINC3; Synonyms=DIFF33, TDE1; ORFNames=SBBI99;
DR   GO; GO:1902237; P:positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
//
ID   SERC4_HUMAN             Reviewed;         518 AA.
AC   A6NH21; B2RN41; Q3YL75;
DE   RecName: Full=Serine incorporator 4;
GN   Name=SERINC4;
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
//
ID   SERC5_HUMAN             Reviewed;         423 AA.
AC   Q86VE9; B4DMH7; Q495A4; Q495A6;
DE   RecName: Full=Serine incorporator 5;
GN   Name=SERINC5; Synonyms=C5orf12;
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0006658; P:phosphatidylserine metabolic process; ISS:HGNC.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0051347; P:positive regulation of transferase activity; ISS:HGNC.
//
ID   SERC_HUMAN              Reviewed;         370 AA.
AC   Q9Y617; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12;
DE   RecName: Full=Phosphoserine aminotransferase;
DE            EC=2.6.1.52;
DE   AltName: Full=Phosphohydroxythreonine aminotransferase;
DE            Short=PSAT;
GN   Name=PSAT1; Synonyms=PSA;
DR   GO; GO:0004648; F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity; NAS:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006564; P:L-serine biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0008615; P:pyridoxine biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SERF1_HUMAN             Reviewed;         110 AA.
AC   O75920; B7ZKM2; O75919; Q52LK5;
DE   RecName: Full=Small EDRK-rich factor 1;
DE   AltName: Full=Protein 4F5;
DE            Short=h4F5;
DE   AltName: Full=SMA modifier 1;
GN   Name=SERF1A; Synonyms=FAM2A, SERF1, SMAM1;
GN   and
GN   Name=SERF1B; Synonyms=FAM2B, SERF1, SMAM1;
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
//
ID   SERF2_HUMAN             Reviewed;          59 AA.
AC   P84101; A6NL45; B5MCG1; B9A026; O75918; O88891; Q9BZH7;
DE   RecName: Full=Small EDRK-rich factor 2;
DE   AltName: Full=Gastric cancer-related protein VRG107;
DE   AltName: Full=Protein 4F5-related;
DE            Short=4F5rel;
DE            Short=h4F5rel;
GN   Name=SERF2; Synonyms=FAM2C;
//
ID   SERHL_HUMAN             Reviewed;         203 AA.
AC   Q9NQF3; Q5JZ95; Q9UH21;
DE   RecName: Full=Serine hydrolase-like protein;
DE            Short=SHL;
DE            EC=3.1.-.-;
GN   Name=SERHL; Synonyms=SERHL2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   SERP1_HUMAN             Reviewed;          66 AA.
AC   Q9Y6X1; D3DNI6;
DE   RecName: Full=Stress-associated endoplasmic reticulum protein 1;
DE   AltName: Full=Ribosome-attached membrane protein 4;
GN   Name=SERP1; Synonyms=RAMP4;
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0007009; P:plasma membrane organization; TAS:ProtInc.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   SERP2_HUMAN             Reviewed;          65 AA.
AC   Q8N6R1;
DE   RecName: Full=Stress-associated endoplasmic reticulum protein 2;
DE   AltName: Full=Ribosome-associated membrane protein RAMP4-2;
GN   Name=SERP2; Synonyms=C13orf21;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SERP3_HUMAN             Reviewed;         424 AA.
AC   A8MV23; B1V8P3;
DE   RecName: Full=Serpin E3;
DE   Flags: Precursor;
GN   Name=SERPINE3;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SERPH_HUMAN             Reviewed;         418 AA.
AC   P50454; B3KVJ3; P29043; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88;
DE   RecName: Full=Serpin H1;
DE   AltName: Full=47 kDa heat shock protein;
DE   AltName: Full=Arsenic-transactivated protein 3;
DE            Short=AsTP3;
DE   AltName: Full=Cell proliferation-inducing gene 14 protein;
DE   AltName: Full=Collagen-binding protein;
DE            Short=Colligin;
DE   AltName: Full=Rheumatoid arthritis-related antigen RA-A47;
DE   Flags: Precursor;
GN   Name=SERPINH1; Synonyms=CBP1, CBP2, HSP47, SERPINH2; ORFNames=PIG14;
DR   GO; GO:0005518; F:collagen binding; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0032964; P:collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0051604; P:protein maturation; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   SESD1_HUMAN             Reviewed;         696 AA.
AC   Q86VW0; Q53R38; Q53SP3; Q5GM69; Q8N6M1; Q96LQ2;
DE   RecName: Full=SEC14 domain and spectrin repeat-containing protein 1;
DE   AltName: Full=Huntingtin-interacting protein-like protein;
DE   AltName: Full=Protein Solo;
GN   Name=SESTD1; Synonyms=SOLO;
DR   GO; GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   SESN1_HUMAN             Reviewed;         492 AA.
AC   Q9Y6P5; Q2M2B7; Q5T316; Q9NV00; Q9UPD5; Q9Y6P6;
DE   RecName: Full=Sestrin-1;
DE   AltName: Full=p53-regulated protein PA26;
GN   Name=SESN1; Synonyms=PA26, SEST1;
DR   GO; GO:0007050; P:cell cycle arrest; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   SESN2_HUMAN             Reviewed;         480 AA.
AC   P58004; Q5T7D0; Q96SI5;
DE   RecName: Full=Sestrin-2;
DE   AltName: Full=Hi95;
GN   Name=SESN2; Synonyms=SEST2;
DR   GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
//
ID   SESN3_HUMAN             Reviewed;         492 AA.
AC   P58005; B7Z7P9; Q96AD1;
DE   RecName: Full=Sestrin-3;
GN   Name=SESN3; Synonyms=SEST3;
DR   GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
//
ID   SESQ1_HUMAN             Reviewed;         249 AA.
AC   Q8N4B1; J3KP50; Q6PJL9; Q96MH8;
DE   RecName: Full=Sesquipedalian-1;
DE            Short=Ses1;
DE   AltName: Full=27 kDa inositol polyphosphate phosphatase-interacting protein A;
DE            Short=IPIP27A;
GN   Name=FAM109A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0001881; P:receptor recycling; IMP:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   SESQ2_HUMAN             Reviewed;         259 AA.
AC   Q6ICB4; Q3SXQ3; Q8N6L9;
DE   RecName: Full=Sesquipedalian-2;
DE            Short=Ses2;
DE   AltName: Full=27 kDa inositol polyphosphate phosphatase interacting protein B;
DE            Short=IPIP27B;
GN   Name=FAM109B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0001881; P:receptor recycling; IMP:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   SET1A_HUMAN             Reviewed;        1707 AA.
AC   O15047; A6NP62; Q6PIF3; Q8TAJ6;
DE   RecName: Full=Histone-lysine N-methyltransferase SETD1A;
DE            EC=2.1.1.43;
DE   AltName: Full=Lysine N-methyltransferase 2F;
DE   AltName: Full=SET domain-containing protein 1A;
DE            Short=hSET1A;
DE   AltName: Full=Set1/Ash2 histone methyltransferase complex subunit SET1;
GN   Name=SETD1A; Synonyms=KIAA0339, KMT2F, SET1, SET1A;
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:GOC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SET1B_HUMAN             Reviewed;        1966 AA.
AC   Q9UPS6; F6MFW1;
DE   RecName: Full=Histone-lysine N-methyltransferase SETD1B;
DE            EC=2.1.1.43;
DE   AltName: Full=Lysine N-methyltransferase 2G;
DE   AltName: Full=SET domain-containing protein 1B;
DE            Short=hSET1B;
GN   Name=SETD1B; Synonyms=KIAA1076, KMT2G, SET1B;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SETB1_HUMAN             Reviewed;        1291 AA.
AC   Q15047; A6NEW2; Q5SZD8; Q5SZD9; Q5SZE0; Q5SZE7; Q96GM9;
DE   RecName: Full=Histone-lysine N-methyltransferase SETDB1;
DE            EC=2.1.1.43;
DE   AltName: Full=ERG-associated protein with SET domain;
DE            Short=ESET;
DE   AltName: Full=Histone H3-K9 methyltransferase 4;
DE            Short=H3-K9-HMTase 4;
DE   AltName: Full=Lysine N-methyltransferase 1E;
DE   AltName: Full=SET domain bifurcated 1;
GN   Name=SETDB1; Synonyms=KIAA0067, KMT1E;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SETB2_HUMAN             Reviewed;         719 AA.
AC   Q96T68; Q5TC65; Q5TC66; Q5W0A7; Q659A7; Q86UD6; Q96AI6;
DE   RecName: Full=Histone-lysine N-methyltransferase SETDB2;
DE            EC=2.1.1.43;
DE   AltName: Full=Chronic lymphocytic leukemia deletion region gene 8 protein;
DE   AltName: Full=Lysine N-methyltransferase 1F;
DE   AltName: Full=SET domain bifurcated 2;
GN   Name=SETDB2; Synonyms=C13orf4, CLLD8, KMT1F;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0001947; P:heart looping; ISS:UniProtKB.
DR   GO; GO:0051567; P:histone H3-K9 methylation; IDA:UniProtKB.
DR   GO; GO:0070986; P:left/right axis specification; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
//
ID   SETBP_HUMAN             Reviewed;        1596 AA.
AC   Q9Y6X0; A6H8W5; Q6P6C3; Q9UEF3;
DE   RecName: Full=SET-binding protein;
DE            Short=SEB;
GN   Name=SETBP1; Synonyms=KIAA0437;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   SETD2_HUMAN             Reviewed;        2564 AA.
AC   Q9BYW2; O75397; O75405; Q17RW8; Q5BKS9; Q5QGN2; Q69YI5; Q6IN64;
AC   Q6ZN53; Q6ZS25; Q8N3R0; Q8TCN0; Q9C0D1; Q9H696; Q9NZW9;
DE   RecName: Full=Histone-lysine N-methyltransferase SETD2;
DE            EC=2.1.1.43;
DE   AltName: Full=HIF-1;
DE   AltName: Full=Huntingtin yeast partner B;
DE   AltName: Full=Huntingtin-interacting protein 1;
DE            Short=HIP-1;
DE   AltName: Full=Huntingtin-interacting protein B;
DE   AltName: Full=Lysine N-methyltransferase 3A;
DE   AltName: Full=SET domain-containing protein 2;
DE            Short=hSET2;
DE   AltName: Full=p231HBP;
GN   Name=SETD2; Synonyms=HIF1, HYPB, KIAA1732, KMT3A, SET2;
GN   ORFNames=HSPC069;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0035441; P:cell migration involved in vasculogenesis; IEA:Ensembl.
DR   GO; GO:0060977; P:coronary vasculature morphogenesis; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0060669; P:embryonic placenta morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0097198; P:histone H3-K36 trimethylation; IDA:UniProtKB.
DR   GO; GO:0048332; P:mesoderm morphogenesis; IEA:Ensembl.
DR   GO; GO:0006298; P:mismatch repair; IMP:UniProtKB.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0034728; P:nucleosome organization; IMP:UniProtKB.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0010793; P:regulation of mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0048864; P:stem cell development; IEA:Ensembl.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:UniProtKB.
//
ID   SETD3_HUMAN             Reviewed;         594 AA.
AC   Q86TU7; A0PJU3; A5PLP0; B4DZE8; Q0VAQ2; Q659C0; Q86TU8; Q96GY9;
AC   Q9H5U5;
DE   RecName: Full=Histone-lysine N-methyltransferase setd3;
DE            EC=2.1.1.43;
DE   AltName: Full=SET domain-containing protein 3;
GN   Name=SETD3; Synonyms=C14orf154;
DR   GO; GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.
DR   GO; GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0010452; P:histone H3-K36 methylation; ISS:UniProtKB.
DR   GO; GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.
DR   GO; GO:0018026; P:peptidyl-lysine monomethylation; ISS:UniProtKB.
DR   GO; GO:0018023; P:peptidyl-lysine trimethylation; ISS:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SETD4_HUMAN             Reviewed;         440 AA.
AC   Q9NVD3; B4DT14; D3DSG2; D3DSG4; Q8NE19; Q9BU46;
DE   RecName: Full=SET domain-containing protein 4;
DE            EC=2.1.1.-;
GN   Name=SETD4; Synonyms=C21orf18, C21orf27;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   SETD5_HUMAN             Reviewed;        1442 AA.
AC   Q9C0A6; Q6AI17; Q8WUB6; Q9H3X4; Q9H6V7; Q9H7S3; Q9NVI9;
DE   RecName: Full=SET domain-containing protein 5;
GN   Name=SETD5; Synonyms=KIAA1757;
//
ID   SETD6_HUMAN             Reviewed;         473 AA.
AC   Q8TBK2; A8K380; B5ME38; Q9H787;
DE   RecName: Full=N-lysine methyltransferase SETD6;
DE            EC=2.1.1.-;
DE   AltName: Full=SET domain-containing protein 6;
GN   Name=SETD6;
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.
//
ID   SETD7_HUMAN             Reviewed;         366 AA.
AC   Q8WTS6; B5WWL3; Q0VAH3; Q4W5A9; Q9C0E6;
DE   RecName: Full=Histone-lysine N-methyltransferase SETD7;
DE            EC=2.1.1.43;
DE   AltName: Full=Histone H3-K4 methyltransferase SETD7;
DE            Short=H3-K4-HMTase SETD7;
DE   AltName: Full=Lysine N-methyltransferase 7;
DE   AltName: Full=SET domain-containing protein 7;
DE   AltName: Full=SET7/9;
GN   Name=SETD7; Synonyms=KIAA1717, KMT7, SET7, SET9;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; NAS:UniProtKB.
DR   GO; GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.
DR   GO; GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SETD8_HUMAN             Reviewed;         393 AA.
AC   Q9NQR1; A8K9D0; Q86W83; Q8TD09;
DE   RecName: Full=N-lysine methyltransferase SETD8;
DE            EC=2.1.1.-;
DE   AltName: Full=H4-K20-HMTase SETD8;
DE   AltName: Full=Histone-lysine N-methyltransferase SETD8;
DE            EC=2.1.1.43;
DE   AltName: Full=Lysine N-methyltransferase 5A;
DE   AltName: Full=PR/SET domain-containing protein 07;
DE            Short=PR-Set7;
DE            Short=PR/SET07;
DE   AltName: Full=SET domain-containing protein 8;
GN   Name=SETD8; Synonyms=KMT5A, PRSET7, SET07, SET8;
DR   GuidetoPHARMACOLOGY; 2704; -.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0034968; P:histone lysine methylation; IDA:GOC.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.
DR   GO; GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SETD9_HUMAN             Reviewed;         299 AA.
AC   Q8NE22; F5H713;
DE   RecName: Full=SET domain-containing protein 9;
DE            EC=2.1.1.-;
GN   Name=SETD9; Synonyms=C5orf35;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   SETLP_HUMAN             Reviewed;         302 AA.
AC   P0DME0;
DE   RecName: Full=Protein SETSIP;
DE   AltName: Full=SET pseudogene protein 18;
DE   AltName: Full=SET similar protein;
DE   AltName: Full=Similar to SET translocation protein;
GN   Name=SETSIP; Synonyms=SETP18;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0045446; P:endothelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SETMR_HUMAN             Reviewed;         684 AA.
AC   Q53H47; B4DY74; E7EN68; Q13579; Q1G668; Q96F41;
DE   RecName: Full=Histone-lysine N-methyltransferase SETMAR;
DE   AltName: Full=SET domain and mariner transposase fusion gene-containing protein;
DE            Short=HsMar1;
DE            Short=Metnase;
DE   Includes:
DE     RecName: Full=Histone-lysine N-methyltransferase;
DE              EC=2.1.1.43;
DE   Includes:
DE     RecName: Full=Mariner transposase Hsmar1;
DE              EC=3.1.-.-;
GN   Name=SETMAR;
DR   GO; GO:0004519; F:endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0043566; F:structure-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0004803; F:transposase activity; TAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:UniProtKB.
DR   GO; GO:0000729; P:DNA double-strand break processing; IDA:UniProtKB.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:2001251; P:negative regulation of chromosome organization; IDA:UniProtKB.
DR   GO; GO:2001034; P:positive regulation of double-strand break repair via nonhomologous end joining; IDA:UniProtKB.
DR   GO; GO:0006313; P:transposition, DNA-mediated; TAS:UniProtKB.
//
ID   SETX_HUMAN              Reviewed;        2677 AA.
AC   Q7Z333; A2A396; B2RPB2; B5ME16; C9JQ10; O75120; Q3KQX4; Q5JUJ1;
AC   Q68DW5; Q6AZD7; Q7Z3J6; Q8WX33; Q9H9D1; Q9NVP9;
DE   RecName: Full=Probable helicase senataxin;
DE            EC=3.6.4.-;
DE   AltName: Full=Amyotrophic lateral sclerosis 4 protein;
DE   AltName: Full=SEN1 homolog;
GN   Name=SETX; Synonyms=ALS4, KIAA0625, SCAR1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IC:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; TAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; IEA:Ensembl.
//
ID   SET_HUMAN               Reviewed;         290 AA.
AC   Q01105; A5A5H4; A6NGV1; B4DUE2; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5;
DE   RecName: Full=Protein SET;
DE   AltName: Full=HLA-DR-associated protein II;
DE   AltName: Full=Inhibitor of granzyme A-activated DNase;
DE            Short=IGAAD;
DE   AltName: Full=PHAPII;
DE   AltName: Full=Phosphatase 2A inhibitor I2PP2A;
DE            Short=I-2PP2A;
DE   AltName: Full=Template-activating factor I;
DE            Short=TAF-I;
GN   Name=SET;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; TAS:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; NAS:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; TAS:ProtInc.
DR   GO; GO:0006337; P:nucleosome disassembly; TAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   SEZ6_HUMAN              Reviewed;         994 AA.
AC   Q53EL9; B6ZDN1; Q8N701; Q8NB57; Q8ND50; Q8TD25; Q96NI5; Q96NQ3;
DE   RecName: Full=Seizure protein 6 homolog;
DE            Short=SEZ-6;
DE            Short=hSEZ-6;
DE   Flags: Precursor;
GN   Name=SEZ6;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:2000171; P:negative regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:1900006; P:positive regulation of dendrite development; IEA:Ensembl.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0060074; P:synapse maturation; IEA:Ensembl.
//
ID   SF01_HUMAN              Reviewed;         639 AA.
AC   Q15637; B7Z1Q1; C9JJE2; Q14818; Q14819; Q15913; Q8IY00; Q92744;
AC   Q92745; Q969H7; Q9BW01; Q9UEI0;
DE   RecName: Full=Splicing factor 1;
DE   AltName: Full=Mammalian branch point-binding protein;
DE            Short=BBP;
DE            Short=mBBP;
DE   AltName: Full=Transcription factor ZFM1;
DE   AltName: Full=Zinc finger gene in MEN1 locus;
DE   AltName: Full=Zinc finger protein 162;
GN   Name=SF1; Synonyms=ZFM1, ZNF162;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0030238; P:male sex determination; IEA:Ensembl.
DR   GO; GO:0000389; P:mRNA 3'-splice site recognition; TAS:HGNC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:HGNC.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0000245; P:spliceosomal complex assembly; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SF3A1_HUMAN             Reviewed;         793 AA.
AC   Q15459; E9PAW1;
DE   RecName: Full=Splicing factor 3A subunit 1;
DE   AltName: Full=SF3a120;
DE   AltName: Full=Spliceosome-associated protein 114;
DE            Short=SAP 114;
GN   Name=SF3A1; Synonyms=SAP114;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000389; P:mRNA 3'-splice site recognition; TAS:HGNC.
DR   GO; GO:0006397; P:mRNA processing; IMP:HGNC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   SF3A2_HUMAN             Reviewed;         464 AA.
AC   Q15428; B2RBU1; D6W605; O75245;
DE   RecName: Full=Splicing factor 3A subunit 2;
DE   AltName: Full=SF3a66;
DE   AltName: Full=Spliceosome-associated protein 62;
DE            Short=SAP 62;
GN   Name=SF3A2; Synonyms=SAP62;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000389; P:mRNA 3'-splice site recognition; TAS:HGNC.
DR   GO; GO:0006397; P:mRNA processing; IMP:HGNC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   SF3A3_HUMAN             Reviewed;         501 AA.
AC   Q12874; D3DPT5; Q15460; Q5VT87;
DE   RecName: Full=Splicing factor 3A subunit 3;
DE   AltName: Full=SF3a60;
DE   AltName: Full=Spliceosome-associated protein 61;
DE            Short=SAP 61;
GN   Name=SF3A3; Synonyms=SAP61;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000389; P:mRNA 3'-splice site recognition; TAS:HGNC.
DR   GO; GO:0006397; P:mRNA processing; IMP:HGNC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   SF3B1_HUMAN             Reviewed;        1304 AA.
AC   O75533; E9PCH3;
DE   RecName: Full=Splicing factor 3B subunit 1;
DE   AltName: Full=Pre-mRNA-splicing factor SF3b 155 kDa subunit;
DE            Short=SF3b155;
DE   AltName: Full=Spliceosome-associated protein 155;
DE            Short=SAP 155;
GN   Name=SF3B1; Synonyms=SAP155;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; NAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; NAS:UniProtKB.
//
ID   SF3B2_HUMAN             Reviewed;         895 AA.
AC   Q13435; A8K485; B4DT19; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2;
DE   RecName: Full=Splicing factor 3B subunit 2;
DE   AltName: Full=Pre-mRNA-splicing factor SF3b 145 kDa subunit;
DE            Short=SF3b145;
DE   AltName: Full=SF3b150;
DE   AltName: Full=Spliceosome-associated protein 145;
DE            Short=SAP 145;
GN   Name=SF3B2; Synonyms=SAP145;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SF3B3_HUMAN             Reviewed;        1217 AA.
AC   Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29;
DE   RecName: Full=Splicing factor 3B subunit 3;
DE   AltName: Full=Pre-mRNA-splicing factor SF3b 130 kDa subunit;
DE            Short=SF3b130;
DE   AltName: Full=STAF130;
DE   AltName: Full=Spliceosome-associated protein 130;
DE            Short=SAP 130;
GN   Name=SF3B3; Synonyms=KIAA0017, SAP130;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   SF3B4_HUMAN             Reviewed;         424 AA.
AC   Q15427; Q5SZ63;
DE   RecName: Full=Splicing factor 3B subunit 4;
DE   AltName: Full=Pre-mRNA-splicing factor SF3b 49 kDa subunit;
DE   AltName: Full=SF3b50;
DE   AltName: Full=Spliceosome-associated protein 49;
DE            Short=SAP 49;
GN   Name=SF3B4; Synonyms=SAP49;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:HGNC.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:ProtInc.
//
ID   SF3B5_HUMAN             Reviewed;          86 AA.
AC   Q9BWJ5; B2R568; Q7RTV1;
DE   RecName: Full=Splicing factor 3B subunit 5;
DE            Short=SF3b5;
DE   AltName: Full=Pre-mRNA-splicing factor SF3b 10 kDa subunit;
GN   Name=SF3B5; Synonyms=SF3B10;
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   SF3B6_HUMAN             Reviewed;         125 AA.
AC   Q9Y3B4; Q53TM1;
DE   RecName: Full=Splicing factor 3B subunit 6;
DE   AltName: Full=Pre-mRNA branch site protein p14;
DE   AltName: Full=SF3b 14 kDa subunit;
DE            Short=SF3B14a;
DE   AltName: Full=Spliceosome-associated protein, 14-kDa;
DE   AltName: Full=Splicing factor 3b, subunit 6, 14kDa;
GN   Name=SF3B6; Synonyms=SAP14, SF3B14, SF3B14A;
GN   ORFNames=CGI-110, HSPC175, HT006;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   SFI1_HUMAN              Reviewed;        1242 AA.
AC   A8K8P3; A1L373; A1L387; A2A2L2; B1AKL9; B5MDB7; B7Z1V6; B7Z8G3;
AC   B7ZBE2; B7ZBE3; O60289; Q2TAN8; Q5W1B5; Q86TK0; Q8N4U8; Q8N8C1;
AC   Q8WU14;
DE   RecName: Full=Protein SFI1 homolog;
DE            Short=hSFI1;
GN   Name=SFI1; Synonyms=KIAA0542;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   SFPA2_HUMAN             Reviewed;         248 AA.
AC   Q8IWL1; A4QPA7; B2RXI6; B2RXK9; C9J9I7; E3VLC6; E3VLC7; E3VLC8;
AC   E3VLC9; P07714; Q14DV3; Q5RIR8; Q5RIR9;
DE   RecName: Full=Pulmonary surfactant-associated protein A2;
DE            Short=PSP-A;
DE            Short=PSPA;
DE            Short=SP-A;
DE            Short=SP-A2;
DE   AltName: Full=35 kDa pulmonary surfactant-associated protein;
DE   AltName: Full=Alveolar proteinosis protein;
DE   AltName: Full=Collectin-5;
DE   Flags: Precursor;
GN   Name=SFTPA2; Synonyms=COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:UniProtKB-KW.
//
ID   SFPQ_HUMAN              Reviewed;         707 AA.
AC   P23246; P30808; Q5SZ71;
DE   RecName: Full=Splicing factor, proline- and glutamine-rich;
DE   AltName: Full=100 kDa DNA-pairing protein;
DE            Short=hPOMp100;
DE   AltName: Full=DNA-binding p52/p100 complex, 100 kDa subunit;
DE   AltName: Full=Polypyrimidine tract-binding protein-associated-splicing factor;
DE            Short=PSF;
DE            Short=PTB-associated-splicing factor;
GN   Name=SFPQ; Synonyms=PSF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IMP:BHF-UCL.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SFR15_HUMAN             Reviewed;        1147 AA.
AC   O95104; C9JLZ0; Q0P5W8; Q6P1M5; Q8N3I8; Q9UFM1; Q9ULP8;
DE   RecName: Full=Splicing factor, arginine/serine-rich 15;
DE   AltName: Full=CTD-binding SR-like protein RA4;
DE   AltName: Full=SR-related and CTD-associated factor 4;
GN   Name=SCAF4; Synonyms=KIAA1172, SFRS15;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   SFR19_HUMAN             Reviewed;        1312 AA.
AC   Q9H7N4; Q7Z5V7; Q8WVA1; Q9NR59;
DE   RecName: Full=Splicing factor, arginine/serine-rich 19;
DE   AltName: Full=SR-related and CTD-associated factor 1;
DE   AltName: Full=SR-related-CTD-associated factor;
DE            Short=SCAF;
DE   AltName: Full=Serine arginine-rich pre-mRNA splicing factor SR-A1;
DE            Short=SR-A1;
GN   Name=SCAF1; Synonyms=SFRS19, SRA1;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   SFR1_HUMAN              Reviewed;         245 AA.
AC   Q86XK3; A8K569; B2RTV8; Q5JT39; Q5JT40; Q8WW47;
DE   RecName: Full=Swi5-dependent recombination DNA repair protein 1 homolog;
DE   AltName: Full=Meiosis protein 5 homolog;
GN   Name=SFR1; Synonyms=C10orf78, MEI5, MEIR5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
//
ID   SFRP1_HUMAN             Reviewed;         314 AA.
AC   Q8N474; O00546; O14779;
DE   RecName: Full=Secreted frizzled-related protein 1;
DE            Short=FRP-1;
DE            Short=sFRP-1;
DE   AltName: Full=Secreted apoptosis-related protein 2;
DE            Short=SARP-2;
DE   Flags: Precursor;
GN   Name=SFRP1; Synonyms=FRP, FRP1, SARP2;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IPI:UniProtKB.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEP:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEP:UniProtKB.
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071504; P:cellular response to heparin; IDA:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEP:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; IEP:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IEP:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0071305; P:cellular response to vitamin D; IEP:UniProtKB.
DR   GO; GO:0071481; P:cellular response to X-ray; IEA:Ensembl.
DR   GO; GO:0090246; P:convergent extension involved in somitogenesis; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IDA:UniProtKB.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IDA:UniProtKB.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0022601; P:menstrual cycle phase; IEP:UniProtKB.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045578; P:negative regulation of B cell differentiation; IMP:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0046851; P:negative regulation of bone remodeling; IMP:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000080; P:negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:2000270; P:negative regulation of fibroblast apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IDA:UniProtKB.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0030279; P:negative regulation of ossification; IDA:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IMP:UniProtKB.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000041; P:negative regulation of planar cell polarity pathway involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000054; P:negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; IDA:UniProtKB.
DR   GO; GO:0014034; P:neural crest cell fate commitment; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:UniProtKB.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; ISS:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IDA:UniProtKB.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; ISS:BHF-UCL.
DR   GO; GO:2000052; P:positive regulation of non-canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; ISS:BHF-UCL.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IMP:GOC.
DR   GO; GO:0045765; P:regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0010564; P:regulation of cell cycle process; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0014070; P:response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0044345; P:stromal-epithelial cell signaling involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IEA:Ensembl.
//
ID   SFRP2_HUMAN             Reviewed;         295 AA.
AC   Q96HF1; B3KQR2; O14778; Q9HAP5;
DE   RecName: Full=Secreted frizzled-related protein 2;
DE            Short=FRP-2;
DE            Short=sFRP-2;
DE   AltName: Full=Secreted apoptosis-related protein 1;
DE            Short=SARP-1;
DE   Flags: Precursor;
GN   Name=SFRP2; Synonyms=FRP2, SARP1; ORFNames=FKSG12, UNQ361/PRO697;
DR   GO; GO:0061133; F:endopeptidase activator activity; IEA:Ensembl.
DR   GO; GO:0001968; F:fibronectin binding; ISS:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; ISS:BHF-UCL.
DR   GO; GO:0010577; F:metalloenzyme activator activity; IEA:Ensembl.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0048018; F:receptor agonist activity; ISS:BHF-UCL.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:BHF-UCL.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0071481; P:cellular response to X-ray; IEA:Ensembl.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0060028; P:convergent extension involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0061185; P:negative regulation of dermatome development; ISS:BHF-UCL.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; ISS:BHF-UCL.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0042662; P:negative regulation of mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:UniProtKB.
DR   GO; GO:2000041; P:negative regulation of planar cell polarity pathway involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:BHF-UCL.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IEA:Ensembl.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; ISS:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IDA:MGI.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:2000035; P:regulation of stem cell division; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0061056; P:sclerotome development; ISS:BHF-UCL.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IEA:Ensembl.
//
ID   SFRP3_HUMAN             Reviewed;         325 AA.
AC   Q92765; O00181; Q99686;
DE   RecName: Full=Secreted frizzled-related protein 3;
DE            Short=sFRP-3;
DE   AltName: Full=Frezzled;
DE   AltName: Full=Fritz;
DE   AltName: Full=Frizzled-related protein 1;
DE   AltName: Full=FrzB-1;
DE   Flags: Precursor;
GN   Name=FRZB; Synonyms=FIZ, FRE, FRP, FRZB1, SFRP3;
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0090103; P:cochlea morphogenesis; IBA:RefGenome.
DR   GO; GO:0060029; P:convergent extension involved in organogenesis; IEA:Ensembl.
DR   GO; GO:0060429; P:epithelium development; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0060056; P:mammary gland involution; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IBA:RefGenome.
DR   GO; GO:0010721; P:negative regulation of cell development; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070367; P:negative regulation of hepatocyte differentiation; IBA:RefGenome.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0014033; P:neural crest cell differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IDA:MGI.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0061053; P:somite development; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   SFRP4_HUMAN             Reviewed;         346 AA.
AC   Q6FHJ7; B4DYC1; O14877; Q05BG7; Q1ZYW2; Q4G124; Q6FHM0; Q6PD64;
DE   RecName: Full=Secreted frizzled-related protein 4;
DE            Short=sFRP-4;
DE   AltName: Full=Frizzled protein, human endometrium;
DE            Short=FrpHE;
DE   Flags: Precursor;
GN   Name=SFRP4; Synonyms=FRPHE;
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0046697; P:decidualization; IBA:RefGenome.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0060429; P:epithelium development; IBA:RefGenome.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0060056; P:mammary gland involution; IBA:RefGenome.
DR   GO; GO:0022601; P:menstrual cycle phase; NAS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:2000119; P:negative regulation of sodium-dependent phosphate transport; IDA:BHF-UCL.
DR   GO; GO:0055062; P:phosphate ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IGI:MGI.
DR   GO; GO:0045606; P:positive regulation of epidermal cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:1902174; P:positive regulation of keratinocyte apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0009725; P:response to hormone; NAS:BHF-UCL.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   SFRP5_HUMAN             Reviewed;         317 AA.
AC   Q5T4F7; O14780; Q86TH7;
DE   RecName: Full=Secreted frizzled-related protein 5;
DE            Short=sFRP-5;
DE   AltName: Full=Frizzled-related protein 1b;
DE            Short=FRP-1b;
DE   AltName: Full=Secreted apoptosis-related protein 3;
DE            Short=SARP-3;
DE   Flags: Precursor;
GN   Name=SFRP5; Synonyms=FRP1B, SARP3;
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0060028; P:convergent extension involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IBA:RefGenome.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:2000041; P:negative regulation of planar cell polarity pathway involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:2000057; P:negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001944; P:vasculature development; IBA:RefGenome.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   SFSWA_HUMAN             Reviewed;         951 AA.
AC   Q12872; B2RN45; B7ZM97; F5H6B8; Q6PJF7;
DE   RecName: Full=Splicing factor, suppressor of white-apricot homolog;
DE   AltName: Full=Splicing factor, arginine/serine-rich 8;
DE   AltName: Full=Suppressor of white apricot protein homolog;
GN   Name=SFSWAP; Synonyms=SFRS8, SWAP;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006376; P:mRNA splice site selection; TAS:ProtInc.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SFT2A_HUMAN             Reviewed;         159 AA.
AC   Q8WV19; Q5TI64; Q9UIC7;
DE   RecName: Full=Vesicle transport protein SFT2A;
DE   AltName: Full=SFT2 domain-containing protein 1;
DE   AltName: Full=pRGR1;
GN   Name=SFT2D1; Synonyms=C6orf83;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   SFT2B_HUMAN             Reviewed;         160 AA.
AC   O95562; A8K2R0; Q6UWR8;
DE   RecName: Full=Vesicle transport protein SFT2B;
DE   AltName: Full=SFT2 domain-containing protein 2;
GN   Name=SFT2D2; ORFNames=UNQ512/PRO1027;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   SFT2C_HUMAN             Reviewed;         215 AA.
AC   Q587I9; Q8N2P9;
DE   RecName: Full=Vesicle transport protein SFT2C;
DE   AltName: Full=SFT2 domain-containing protein 3;
GN   Name=SFT2D3;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   SFTA1_HUMAN             Reviewed;         248 AA.
AC   Q8IWL2; A8K3T8; B7ZW50; E3VLD8; E3VLD9; E3VLE0; E3VLE1; G5E9J3;
AC   P07714; Q14DV4; Q5RIR5; Q5RIR7; Q6PIT0; Q8TC19;
DE   RecName: Full=Pulmonary surfactant-associated protein A1;
DE            Short=PSP-A;
DE            Short=PSPA;
DE            Short=SP-A;
DE            Short=SP-A1;
DE   AltName: Full=35 kDa pulmonary surfactant-associated protein;
DE   AltName: Full=Alveolar proteinosis protein;
DE   AltName: Full=Collectin-4;
DE   Flags: Precursor;
GN   Name=SFTPA1; Synonyms=COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; TAS:GOC.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:UniProtKB-KW.
//
ID   SFTA2_HUMAN             Reviewed;          78 AA.
AC   Q6UW10; A2ABK7; A2ACH1; B7ZCJ7;
DE   RecName: Full=Surfactant-associated protein 2;
DE   AltName: Full=Surfactant-associated protein G;
DE            Short=SP-G;
DE   Flags: Precursor;
GN   Name=SFTA2; Synonyms=SFTPG; ORFNames=UNQ541/PRO1098;
//
ID   SFTA3_HUMAN             Reviewed;          94 AA.
AC   P0C7M3;
DE   RecName: Full=Putative protein SFTA3;
DE   AltName: Full=Surfactant-associated protein 3;
DE   AltName: Full=Surfactant-associated protein H;
GN   Name=SFTA3; Synonyms=SFTPH;
//
ID   SFTPD_HUMAN             Reviewed;         375 AA.
AC   P35247; Q5T0M3; Q6FH08; Q86YK9; Q8TCD8; Q9UCJ2; Q9UCJ3;
DE   RecName: Full=Pulmonary surfactant-associated protein D;
DE            Short=PSP-D;
DE            Short=SP-D;
DE   AltName: Full=Collectin-7;
DE   AltName: Full=Lung surfactant protein D;
DE   Flags: Precursor;
GN   Name=SFTPD; Synonyms=COLEC7, PSPD, SFTP4;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0048286; P:lung alveolus development; IMP:UniProtKB.
DR   GO; GO:0048246; P:macrophage chemotaxis; TAS:UniProtKB.
DR   GO; GO:0045085; P:negative regulation of interleukin-2 biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; TAS:UniProtKB.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; TAS:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; TAS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0001817; P:regulation of cytokine production; NAS:UniProtKB.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:UniProtKB-KW.
DR   GO; GO:0043129; P:surfactant homeostasis; IMP:UniProtKB.
//
ID   SFXN1_HUMAN             Reviewed;         322 AA.
AC   Q9H9B4; B3KPW3; D3DQN2; Q9HA53;
DE   RecName: Full=Sideroflexin-1;
DE   AltName: Full=Tricarboxylate carrier protein;
DE            Short=TCC;
GN   Name=SFXN1;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0006826; P:iron ion transport; IEA:Ensembl.
//
ID   SFXN2_HUMAN             Reviewed;         322 AA.
AC   Q96NB2; Q5JSM6;
DE   RecName: Full=Sideroflexin-2;
GN   Name=SFXN2;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
//
ID   SFXN3_HUMAN             Reviewed;         325 AA.
AC   Q9BWM7; Q8NCJ0; Q9NTP4;
DE   RecName: Full=Sideroflexin-3;
GN   Name=SFXN3;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
//
ID   SFXN4_HUMAN             Reviewed;         337 AA.
AC   Q6P4A7; Q6WSU4; Q86TD9;
DE   RecName: Full=Sideroflexin-4;
DE   AltName: Full=Breast cancer resistance marker 1;
GN   Name=SFXN4; Synonyms=BCRM1;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
//
ID   SFXN5_HUMAN             Reviewed;         340 AA.
AC   Q8TD22; A8K116; Q494Y3; Q53T29;
DE   RecName: Full=Sideroflexin-5;
GN   Name=SFXN5;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015137; F:citrate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
//
ID   SG11A_HUMAN             Reviewed;         123 AA.
AC   Q6PDA7; A6NIY0;
DE   RecName: Full=Sperm-associated antigen 11A;
DE   AltName: Full=Human epididymis-specific protein 2;
DE            Short=He2;
DE   AltName: Full=Protein EP2;
DE   AltName: Full=Sperm antigen HE2;
DE   Flags: Precursor;
GN   Name=SPAG11A; Synonyms=EP2, HE2;
//
ID   SG11B_HUMAN             Reviewed;         103 AA.
AC   Q08648; E9PFH0; Q546A0; Q6ZYB2; Q9H4P8; Q9H4P9; Q9H4Q0; Q9H4Q1;
AC   Q9H4Q2; Q9NRT3; Q9NRV4; Q9NRV5; Q9NRV6; Q9NRV7; Q9NRV8;
DE   RecName: Full=Sperm-associated antigen 11B;
DE   AltName: Full=Human epididymis-specific protein 2;
DE            Short=He2;
DE   AltName: Full=Protein EP2;
DE   AltName: Full=Sperm antigen HE2;
DE   Flags: Precursor;
GN   Name=SPAG11B; Synonyms=EP2, HE2;
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   SG196_HUMAN             Reviewed;         350 AA.
AC   Q9H5K3;
DE   RecName: Full=Protein O-mannose kinase;
DE            Short=POMK;
DE            EC=2.7.1.-;
DE   AltName: Full=Protein kinase-like protein SgK196;
DE   AltName: Full=Sugen kinase 196;
GN   Name=POMK; Synonyms=SGK196;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; TAS:UniProtKB.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
//
ID   SG1C1_HUMAN             Reviewed;          95 AA.
AC   Q8TD33; A8MSI9; Q14DW0;
DE   RecName: Full=Secretoglobin family 1C member 1;
DE   AltName: Full=Secretoglobin RYD5;
DE   Flags: Precursor;
GN   Name=SCGB1C1;
//
ID   SG1D4_HUMAN             Reviewed;          83 AA.
AC   Q6XE38; A1L4Q8;
DE   RecName: Full=Secretoglobin family 1D member 4;
DE   AltName: Full=IFN-gamma-inducible secretoglobin;
DE            Short=IIS;
DE   Flags: Precursor;
GN   Name=SCGB1D4; ORFNames=UNQ517/PRO812;
//
ID   SG1D1_HUMAN             Reviewed;          90 AA.
AC   O95968;
DE   RecName: Full=Secretoglobin family 1D member 1;
DE   AltName: Full=Lipophilin-A;
DE   Flags: Precursor;
GN   Name=SCGB1D1; Synonyms=LIPHA, LPNA;
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProt.
//
ID   SG1D2_HUMAN             Reviewed;          90 AA.
AC   O95969; Q2M3N9;
DE   RecName: Full=Secretoglobin family 1D member 2;
DE   AltName: Full=Lipophilin-B;
DE   Flags: Precursor;
GN   Name=SCGB1D2; Synonyms=LIPHB, LPNB;
//
ID   SG223_HUMAN             Reviewed;        1402 AA.
AC   Q86YV5; Q8N3N5;
DE   RecName: Full=Tyrosine-protein kinase SgK223;
DE            EC=2.7.10.2;
DE   AltName: Full=Sugen kinase 223;
GN   Name=SGK223;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
//
ID   SG2A1_HUMAN             Reviewed;          95 AA.
AC   O75556;
DE   RecName: Full=Mammaglobin-B;
DE   AltName: Full=Lacryglobin;
DE   AltName: Full=Lipophilin-C;
DE   AltName: Full=Mammaglobin-2;
DE   AltName: Full=Secretoglobin family 2A member 1;
DE   Flags: Precursor;
GN   Name=SCGB2A1; Synonyms=LIPHC, MGB2, UGB3;
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProt.
DR   GO; GO:0005496; F:steroid binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProt.
//
ID   SG2A2_HUMAN             Reviewed;          93 AA.
AC   Q13296; A1A522; Q86WH8;
DE   RecName: Full=Mammaglobin-A;
DE   AltName: Full=Mammaglobin-1;
DE   AltName: Full=Secretoglobin family 2A member 2;
DE   Flags: Precursor;
GN   Name=SCGB2A2; Synonyms=MGB1, UGB2;
//
ID   SG3A1_HUMAN             Reviewed;         104 AA.
AC   Q96QR1; Q96PL0;
DE   RecName: Full=Secretoglobin family 3A member 1;
DE   AltName: Full=Cytokine HIN-1;
DE   AltName: Full=High in normal 1;
DE   AltName: Full=Pneumo secretory protein 2;
DE            Short=PnSP-2;
DE   AltName: Full=Uteroglobin-related protein 2;
DE   Flags: Precursor;
GN   Name=SCGB3A1; Synonyms=HIN1, PNSP2, UGRP2; ORFNames=UNQ629/PRO1245;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.
//
ID   SG3A2_HUMAN             Reviewed;          93 AA.
AC   Q96PL1;
DE   RecName: Full=Secretoglobin family 3A member 2;
DE   AltName: Full=Pneumo secretory protein 1;
DE            Short=PnSP-1;
DE   AltName: Full=Uteroglobin-related protein 1;
DE   Flags: Precursor;
GN   Name=SCGB3A2; Synonyms=PNSP1, UGRP1; ORFNames=UNQ566/PRO1128;
//
ID   SG494_HUMAN             Reviewed;         274 AA.
AC   Q96LW2; B4DFP4; Q49A48;
DE   RecName: Full=Uncharacterized serine/threonine-protein kinase SgK494;
DE            EC=2.7.11.1;
DE   AltName: Full=Sugen kinase 494;
GN   Name=SGK494;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   SGCA_HUMAN              Reviewed;         387 AA.
AC   Q16586; A6NEB8; A8K3K7; Q13710; Q13712;
DE   RecName: Full=Alpha-sarcoglycan;
DE            Short=Alpha-SG;
DE   AltName: Full=50 kDa dystrophin-associated glycoprotein;
DE            Short=50DAG;
DE   AltName: Full=Adhalin;
DE   AltName: Full=Dystroglycan-2;
DE   Flags: Precursor;
GN   Name=SGCA; Synonyms=ADL, DAG2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   SGCD_HUMAN              Reviewed;         289 AA.
AC   Q92629; A8K9S9; Q53XA5; Q99644;
DE   RecName: Full=Delta-sarcoglycan;
DE            Short=Delta-SG;
DE   AltName: Full=35 kDa dystrophin-associated glycoprotein;
DE            Short=35DAG;
GN   Name=SGCD;
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   SGCB_HUMAN              Reviewed;         318 AA.
AC   Q16585; O00661;
DE   RecName: Full=Beta-sarcoglycan;
DE            Short=Beta-SG;
DE   AltName: Full=43 kDa dystrophin-associated glycoprotein;
DE            Short=43DAG;
DE   AltName: Full=A3b;
GN   Name=SGCB;
DR   GO; GO:0035051; P:cardiocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   SGCE_HUMAN              Reviewed;         437 AA.
AC   O43556; B2R8N2; D6W5Q8; E9PF60; G5E9K6; Q6L8P0; Q75MH8; Q8NFG8;
AC   Q8WW28;
DE   RecName: Full=Epsilon-sarcoglycan;
DE            Short=Epsilon-SG;
GN   Name=SGCE; Synonyms=ESG; ORFNames=UNQ433/PRO840;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   SGCG_HUMAN              Reviewed;         291 AA.
AC   Q13326; Q32M32; Q5T9J6;
DE   RecName: Full=Gamma-sarcoglycan;
DE            Short=Gamma-SG;
DE   AltName: Full=35 kDa dystrophin-associated glycoprotein;
DE            Short=35DAG;
GN   Name=SGCG;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   SGCZ_HUMAN              Reviewed;         299 AA.
AC   Q96LD1; Q6REU0;
DE   RecName: Full=Zeta-sarcoglycan;
DE            Short=Zeta-SG;
DE   AltName: Full=ZSG1;
GN   Name=SGCZ;
DR   GO; GO:0061024; P:membrane organization; TAS:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; TAS:BHF-UCL.
DR   GO; GO:0055001; P:muscle cell development; TAS:BHF-UCL.
//
ID   SGE1L_HUMAN             Reviewed;         616 AA.
AC   A6NJ88;
DE   RecName: Full=Putative SAGE1-like protein;
//
ID   SGF29_HUMAN             Reviewed;         293 AA.
AC   Q96ES7; Q96MF5;
DE   RecName: Full=SAGA-associated factor 29 homolog;
DE   AltName: Full=Coiled-coil domain-containing protein 101;
GN   Name=CCDC101; Synonyms=SGF29;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0071169; P:establishment of protein localization to chromatin; TAS:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SGIP1_HUMAN             Reviewed;         828 AA.
AC   Q9BQI5; A6NL81; A6NLD1; Q4LE32; Q5VYE2; Q5VYE3; Q5VYE4; Q68D76;
AC   Q6MZY6; Q8IWC2;
DE   RecName: Full=SH3-containing GRB2-like protein 3-interacting protein 1;
DE   AltName: Full=Endophilin-3-interacting protein;
GN   Name=SGIP1;
DR   GO; GO:0008017; F:microtubule binding; ISS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:2000507; P:positive regulation of energy homeostasis; ISS:UniProtKB.
DR   GO; GO:2000253; P:positive regulation of feeding behavior; ISS:UniProtKB.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; ISS:UniProtKB.
DR   GO; GO:0002021; P:response to dietary excess; ISS:UniProtKB.
//
ID   SGK1_HUMAN              Reviewed;         431 AA.
AC   O00141; B7UUP7; B7UUP8; B7UUP9; B7Z5B2; E1P583; Q5TCN2; Q5TCN3;
AC   Q5TCN4; Q5VY65; Q9UN56;
DE   RecName: Full=Serine/threonine-protein kinase Sgk1;
DE            EC=2.7.11.1;
DE   AltName: Full=Serum/glucocorticoid-regulated kinase 1;
GN   Name=SGK1; Synonyms=SGK;
DR   GuidetoPHARMACOLOGY; 1534; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007616; P:long-term memory; TAS:UniProtKB.
DR   GO; GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0060453; P:regulation of gastric acid secretion; TAS:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0070294; P:renal sodium ion absorption; TAS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SGK2_HUMAN              Reviewed;         427 AA.
AC   Q9HBY8; Q52PK5; Q5H8Y6; Q5H8Z1; Q5TZR3; Q9UKG6;
DE   RecName: Full=Serine/threonine-protein kinase Sgk2;
DE            EC=2.7.11.1;
DE   AltName: Full=Serum/glucocorticoid-regulated kinase 2;
GN   Name=SGK2;
DR   GuidetoPHARMACOLOGY; 1535; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0017080; F:sodium channel regulator activity; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SGK3_HUMAN              Reviewed;         496 AA.
AC   Q96BR1; A8K5W3; B3KQC2; Q9P1Q7; Q9UKG5;
DE   RecName: Full=Serine/threonine-protein kinase Sgk3;
DE            EC=2.7.11.1;
DE   AltName: Full=Cytokine-independent survival kinase;
DE   AltName: Full=Serum/glucocorticoid-regulated kinase 3;
DE   AltName: Full=Serum/glucocorticoid-regulated kinase-like;
GN   Name=SGK3; Synonyms=CISK, SGKL;
DR   GuidetoPHARMACOLOGY; 1536; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005246; F:calcium channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0017081; F:chloride channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015459; F:potassium channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0017080; F:sodium channel regulator activity; TAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SGK71_HUMAN             Reviewed;         680 AA.
AC   Q8NE28; Q5T8U8; Q6ZMP6; Q6ZMQ5;
DE   RecName: Full=Probable inactive protein kinase-like protein SgK071;
DE   AltName: Full=Sugen kinase 071;
GN   Name=SGK071; Synonyms=C9orf96;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
//
ID   SGMR1_HUMAN             Reviewed;         223 AA.
AC   Q99720; D3DRM7; O00673; O00725; Q0Z9W6; Q153Z1; Q2TSD1; Q53GN2;
AC   Q7Z653; Q8N7H3; Q9NYX0;
DE   RecName: Full=Sigma non-opioid intracellular receptor 1;
DE   AltName: Full=Aging-associated gene 8 protein;
DE   AltName: Full=SR31747-binding protein;
DE            Short=SR-BP;
DE   AltName: Full=Sigma 1-type opioid receptor;
DE            Short=SIG-1R;
DE            Short=Sigma1-receptor;
DE            Short=Sigma1R;
DE            Short=hSigmaR1;
GN   Name=SIGMAR1; Synonyms=OPRS1, SRBP; ORFNames=AAG8;
DR   GuidetoPHARMACOLOGY; 2552; -.
DR   GO; GO:0008144; F:drug binding; TAS:ProtInc.
DR   GO; GO:0004985; F:opioid receptor activity; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IMP:UniProtKB.
//
ID   SGOL1_HUMAN             Reviewed;         561 AA.
AC   Q5FBB7; Q588H5; Q5FBB4; Q5FBB5; Q5FBB6; Q5FBB8; Q8N579; Q8WVL0;
AC   Q9BVA8; Q9H275;
DE   RecName: Full=Shugoshin-like 1;
DE            Short=hSgo1;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-85;
GN   Name=SGOL1; Synonyms=SGO1;
DR   GO; GO:0019900; F:kinase binding; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IDA:UniProtKB.
DR   GO; GO:0010457; P:centriole-centriole cohesion; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IDA:UniProtKB.
DR   GO; GO:0045132; P:meiotic chromosome segregation; IMP:MGI.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   SGOL2_HUMAN             Reviewed;        1265 AA.
AC   Q562F6; Q53RR9; Q53T20; Q86XY4; Q8IWK2; Q8IZK1; Q8N1Q5; Q96LQ3;
DE   RecName: Full=Shugoshin-like 2;
DE   AltName: Full=Shugoshin-2;
DE            Short=Sgo2;
DE   AltName: Full=Tripin;
GN   Name=SGOL2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   SGPL1_HUMAN             Reviewed;         568 AA.
AC   O95470; B2RBD4; Q7Z732; Q9ULG8; Q9UN89;
DE   RecName: Full=Sphingosine-1-phosphate lyase 1;
DE            Short=S1PL;
DE            Short=SP-lyase 1;
DE            Short=SPL 1;
DE            Short=hSPL;
DE            EC=4.1.2.27;
DE   AltName: Full=Sphingosine-1-phosphate aldolase;
GN   Name=SGPL1; Synonyms=KIAA1252;
DR   GO; GO:0016831; F:carboxy-lyase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008117; F:sphinganine-1-phosphate aldolase activity; IDA:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; IEA:Ensembl.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   GO; GO:0006672; P:ceramide metabolic process; IDA:UniProtKB.
DR   GO; GO:0008210; P:estrogen metabolic process; IEA:Ensembl.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0001553; P:luteinization; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0030149; P:sphingolipid catabolic process; NAS:UniProtKB.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   SGPP1_HUMAN             Reviewed;         441 AA.
AC   Q9BX95; B2RAH0; Q9H189;
DE   RecName: Full=Sphingosine-1-phosphate phosphatase 1;
DE            Short=SPPase1;
DE            Short=Spp1;
DE            Short=hSPP1;
DE            Short=hSPPase1;
DE            EC=3.1.3.-;
DE   AltName: Full=Sphingosine-1-phosphatase 1;
GN   Name=SGPP1;
DR   GO; GO:0042392; F:sphingosine-1-phosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006668; P:sphinganine-1-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006670; P:sphingosine metabolic process; IEA:Ensembl.
//
ID   SGPP2_HUMAN             Reviewed;         399 AA.
AC   Q8IWX5; A3KPB4; Q8N8Q6;
DE   RecName: Full=Sphingosine-1-phosphate phosphatase 2;
DE            Short=SPPase2;
DE            Short=Spp2;
DE            Short=hSPP2;
DE            EC=3.1.3.-;
DE   AltName: Full=Sphingosine-1-phosphatase 2;
GN   Name=SGPP2;
DR   GO; GO:0042392; F:sphingosine-1-phosphate phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006670; P:sphingosine metabolic process; IDA:UniProtKB.
//
ID   SGSM2_HUMAN             Reviewed;        1006 AA.
AC   O43147; A5LGW2; B4DH69; Q49AC2; Q6ZUY2; Q8IXU4;
DE   RecName: Full=Small G protein signaling modulator 2;
DE   AltName: Full=RUN and TBC1 domain-containing protein 1;
GN   Name=SGSM2; Synonyms=KIAA0397, RUTBC1;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   SGSM3_HUMAN             Reviewed;         749 AA.
AC   Q96HU1; B0QY79; Q7Z709; Q9NT69;
DE   RecName: Full=Small G protein signaling modulator 3;
DE   AltName: Full=Merlin-associated protein;
DE   AltName: Full=RUN and TBC1 domain-containing protein 3;
DE   AltName: Full=Rab-GTPase-activating protein-like protein;
DE            Short=RabGAPLP;
GN   Name=SGSM3; Synonyms=MAP, RABGAPLP, RUTBC3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB.
DR   GO; GO:0032483; P:regulation of Rab protein signal transduction; IEP:UniProtKB.
//
ID   SGT1_HUMAN              Reviewed;         644 AA.
AC   O95905; C9JX46; E9PAW8;
DE   RecName: Full=Protein SGT1;
DE            Short=hSGT1;
DE   AltName: Full=Protein ecdysoneless homolog;
DE   AltName: Full=Suppressor of GCR2;
GN   Name=ECD; Synonyms=SGT1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0006110; P:regulation of glycolytic process; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   SGSM1_HUMAN             Reviewed;        1148 AA.
AC   Q2NKQ1; A5LGW1; A8MUT4; B0QYW0; B0QYW1; B5MEG1; B9A6J4; Q5TFL3;
AC   Q8TF60;
DE   RecName: Full=Small G protein signaling modulator 1;
DE   AltName: Full=RUN and TBC1 domain-containing protein 2;
GN   Name=SGSM1; Synonyms=KIAA1941, RUTBC2;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   SGTA_HUMAN              Reviewed;         313 AA.
AC   O43765; D6W610; Q6FIA9; Q9BTZ9;
DE   RecName: Full=Small glutamine-rich tetratricopeptide repeat-containing protein alpha;
DE   AltName: Full=Alpha-SGT;
DE   AltName: Full=Vpu-binding protein;
DE            Short=UBP;
GN   Name=SGTA; Synonyms=SGT, SGT1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SGTB_HUMAN              Reviewed;         304 AA.
AC   Q96EQ0;
DE   RecName: Full=Small glutamine-rich tetratricopeptide repeat-containing protein beta;
DE   AltName: Full=Beta-SGT;
DE   AltName: Full=Small glutamine-rich protein with tetratricopeptide repeats 2;
GN   Name=SGTB; Synonyms=SGT2;
//
ID   SH21A_HUMAN             Reviewed;         128 AA.
AC   O60880; A8MSW0; O95383; O95384; O95385; O95386; Q6FGS6; Q9UNR0;
DE   RecName: Full=SH2 domain-containing protein 1A;
DE   AltName: Full=Duncan disease SH2-protein;
DE   AltName: Full=Signaling lymphocytic activation molecule-associated protein;
DE            Short=SLAM-associated protein;
DE   AltName: Full=T-cell signal transduction molecule SAP;
GN   Name=SH2D1A; Synonyms=DSHP, SAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0006968; P:cellular defense response; NAS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; NAS:GOC.
//
ID   SH21B_HUMAN             Reviewed;         132 AA.
AC   O14796; B2RBN6; Q5T0L1; Q8NI18; Q969K9;
DE   RecName: Full=SH2 domain-containing protein 1B;
DE   AltName: Full=EWS/FLI1-activated transcript 2;
DE            Short=EAT-2;
GN   Name=SH2D1B; Synonyms=EAT2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030674; F:protein binding, bridging; TAS:UniProtKB.
DR   GO; GO:0002366; P:leukocyte activation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0045089; P:positive regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0002717; P:positive regulation of natural killer cell mediated immunity; ISS:UniProtKB.
//
ID   SH22A_HUMAN             Reviewed;         389 AA.
AC   Q9NP31; O43817; Q5UBZ1; Q5VZS4; Q5VZS5; Q9UPA7;
DE   RecName: Full=SH2 domain-containing protein 2A;
DE   AltName: Full=SH2 domain-containing adapter protein;
DE   AltName: Full=T cell-specific adapter protein;
DE            Short=TSAd;
DE   AltName: Full=VEGF receptor-associated protein;
GN   Name=SH2D2A; Synonyms=SCAP, TSAD, VRAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SH23A_HUMAN             Reviewed;         576 AA.
AC   Q9BRG2; A8K9R6; Q9Y2X4;
DE   RecName: Full=SH2 domain-containing protein 3A;
DE   AltName: Full=Novel SH2-containing protein 1;
GN   Name=SH2D3A; Synonyms=NSP1; ORFNames=UNQ175/PRO201;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   SH24A_HUMAN             Reviewed;         454 AA.
AC   Q9H788; B4DDR1; Q5XKC1; Q6NXE9; Q86YM2; Q96C88; Q9H7F7;
DE   RecName: Full=SH2 domain-containing protein 4A;
DE   AltName: Full=Protein SH(2)A;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 38;
GN   Name=SH2D4A; Synonyms=PPP1R38, SH2A;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   SH24B_HUMAN             Reviewed;         431 AA.
AC   Q5SQS7; Q5SQS5; Q6ZVW9; Q6ZVZ3;
DE   RecName: Full=SH2 domain-containing protein 4B;
GN   Name=SH2D4B;
//
ID   SH2B1_HUMAN             Reviewed;         756 AA.
AC   Q9NRF2; A8K2R7; Q96FK3; Q96SX3; Q9NRF1; Q9NRF3; Q9P2P7; Q9Y3Y3;
DE   RecName: Full=SH2B adapter protein 1;
DE   AltName: Full=Pro-rich, PH and SH2 domain-containing signaling mediator;
DE            Short=PSM;
DE   AltName: Full=SH2 domain-containing protein 1B;
GN   Name=SH2B1; Synonyms=KIAA1299, SH2B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitosis; IEA:Ensembl.
DR   GO; GO:2000278; P:regulation of DNA biosynthetic process; IEA:Ensembl.
//
ID   SH2B2_HUMAN             Reviewed;         632 AA.
AC   O14492; A6ND74;
DE   RecName: Full=SH2B adapter protein 2;
DE   AltName: Full=Adapter protein with pleckstrin homology and Src homology 2 domains;
DE   AltName: Full=SH2 and PH domain-containing adapter protein APS;
GN   Name=SH2B2; Synonyms=APS;
DR   GO; GO:0008269; F:JAK pathway signal transduction adaptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IDA:GOC.
DR   GO; GO:0046425; P:regulation of JAK-STAT cascade; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SH2B3_HUMAN             Reviewed;         575 AA.
AC   Q9UQQ2; B9EGG5; O95184;
DE   RecName: Full=SH2B adapter protein 3;
DE   AltName: Full=Lymphocyte adapter protein;
DE   AltName: Full=Lymphocyte-specific adapter protein Lnk;
DE   AltName: Full=Signal transduction protein Lnk;
GN   Name=SH2B3; Synonyms=LNK;
DR   GO; GO:0042301; F:phosphate ion binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
//
ID   SH2D3_HUMAN             Reviewed;         860 AA.
AC   Q8N5H7; A8K5S8; E9PG48; Q5HYE5; Q5JU31; Q6UY42; Q8N6X3; Q9Y2X5;
DE   RecName: Full=SH2 domain-containing protein 3C;
DE   AltName: Full=Novel SH2-containing protein 3;
DE   AltName: Full=SH2 domain-containing Eph receptor-binding protein 1;
DE            Short=SHEP1;
GN   Name=SH2D3C; Synonyms=NSP3; ORFNames=UNQ272/PRO309/PRO34088;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007254; P:JNK cascade; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   SH2D5_HUMAN             Reviewed;         423 AA.
AC   Q6ZV89; B7Z3W3; Q5SSJ2;
DE   RecName: Full=SH2 domain-containing protein 5;
GN   Name=SH2D5;
//
ID   SH2D7_HUMAN             Reviewed;         451 AA.
AC   A6NKC9;
DE   RecName: Full=SH2 domain-containing protein 7;
GN   Name=SH2D7;
//
ID   SH2D6_HUMAN             Reviewed;         175 AA.
AC   Q7Z4S9; A6ND14; Q6R306;
DE   RecName: Full=SH2 domain-containing protein 6;
GN   Name=SH2D6;
//
ID   SH321_HUMAN             Reviewed;         640 AA.
AC   A4FU49; B4DLI6; D3DPS6; J3KQM5; Q5VTK7; Q86XZ6; Q8N445; Q96DN4;
AC   Q9H5W5;
DE   RecName: Full=SH3 domain-containing protein 21;
GN   Name=SH3D21; Synonyms=C1orf113;
//
ID   SH319_HUMAN             Reviewed;         790 AA.
AC   Q5HYK7; B7Z296; Q08EK1; Q32N10; Q5U3B8; Q86XB3; Q8N5E7; Q9UFC8;
DE   RecName: Full=SH3 domain-containing protein 19;
DE   AltName: Full=ADAM-binding protein Eve-1;
DE   AltName: Full=EEN-binding protein;
DE            Short=EBP;
GN   Name=SH3D19;
DR   GO; GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   SH3B4_HUMAN             Reviewed;         963 AA.
AC   Q9P0V3; O95082; Q309A3; Q53QD0; Q53TD1;
DE   RecName: Full=SH3 domain-binding protein 4;
DE   AltName: Full=EH-binding protein 10;
DE   AltName: Full=Transferrin receptor-trafficking protein;
GN   Name=SH3BP4; Synonyms=BOG25, EHB10, TTP;
DR   GO; GO:0005092; F:GDP-dissociation inhibitor activity; IMP:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017016; F:Ras GTPase binding; IPI:UniProtKB.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0061462; P:protein localization to lysosome; IMP:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; IMP:UniProtKB.
//
ID   SH3BG_HUMAN             Reviewed;         239 AA.
AC   P55822; A6ND59; D3DSI2; Q9BRB8;
DE   RecName: Full=SH3 domain-binding glutamic acid-rich protein;
DE            Short=SH3BGR protein;
DE   AltName: Full=21-glutamic acid-rich protein;
DE            Short=21-GARP;
GN   Name=SH3BGR;
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   SH3G1_HUMAN             Reviewed;         368 AA.
AC   Q99961; B4DRA1; E7EVZ4; M0QZV5; Q99668;
DE   RecName: Full=Endophilin-A2;
DE   AltName: Full=EEN fusion partner of MLL;
DE   AltName: Full=Endophilin-2;
DE   AltName: Full=Extra eleven-nineteen leukemia fusion gene protein;
DE            Short=EEN;
DE   AltName: Full=SH3 domain protein 2B;
DE   AltName: Full=SH3 domain-containing GRB2-like protein 1;
GN   Name=SH3GL1; Synonyms=CNSA1, SH3D2B;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SH3G2_HUMAN             Reviewed;         352 AA.
AC   Q99962; B2R618; Q9NQK5;
DE   RecName: Full=Endophilin-A1;
DE   AltName: Full=EEN-B1;
DE   AltName: Full=Endophilin-1;
DE   AltName: Full=SH3 domain protein 2A;
DE   AltName: Full=SH3 domain-containing GRB2-like protein 2;
GN   Name=SH3GL2; Synonyms=CNSA2, SH3D2A;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0002090; P:regulation of receptor internalization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IEA:Ensembl.
//
ID   SH3G3_HUMAN             Reviewed;         347 AA.
AC   Q99963; O43553; O43554;
DE   RecName: Full=Endophilin-A3;
DE   AltName: Full=EEN-B2;
DE   AltName: Full=Endophilin-3;
DE   AltName: Full=SH3 domain protein 2C;
DE   AltName: Full=SH3 domain-containing GRB2-like protein 3;
GN   Name=SH3GL3; Synonyms=CNSA3, SH3D2C;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SH3K1_HUMAN             Reviewed;         665 AA.
AC   Q96B97; B7Z1D5; Q5JPT4; Q5JPT5; Q8IWX6; Q8IX98; Q96RN4; Q9NYR0;
DE   RecName: Full=SH3 domain-containing kinase-binding protein 1;
DE   AltName: Full=CD2-binding protein 3;
DE            Short=CD2BP3;
DE   AltName: Full=Cbl-interacting protein of 85 kDa;
DE   AltName: Full=Human Src family kinase-binding protein 1;
DE            Short=HSB-1;
GN   Name=SH3KBP1; Synonyms=CIN85;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   SH3L1_HUMAN             Reviewed;         114 AA.
AC   O75368; Q3SYL1; Q5JT50; Q6FIE8; Q9H0N8;
DE   RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;
GN   Name=SH3BGRL;
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
//
ID   SH3L2_HUMAN             Reviewed;         107 AA.
AC   Q9UJC5; A8MQU2; Q2VPC2; Q5VV96; Q6NSK8; Q6P9E8; Q7Z734; Q8IWD3;
AC   Q9BPY5;
DE   RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 2;
DE   AltName: Full=Fovea-associated SH3 domain-binding protein;
GN   Name=SH3BGRL2; Synonyms=FASH3;
//
ID   SH3L3_HUMAN             Reviewed;          93 AA.
AC   Q9H299; Q5T122;
DE   RecName: Full=SH3 domain-binding glutamic acid-rich-like protein 3;
DE   AltName: Full=SH3 domain-binding protein 1;
DE            Short=SH3BP-1;
GN   Name=SH3BGRL3; ORFNames=P1725;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   SH3R1_HUMAN             Reviewed;         888 AA.
AC   Q7Z6J0; Q05BT2; Q8IW46; Q9HAM2; Q9P234;
DE   RecName: Full=E3 ubiquitin-protein ligase SH3RF1;
DE            EC=6.3.2.-;
DE   AltName: Full=Plenty of SH3s;
DE            Short=Protein POSH;
DE   AltName: Full=RING finger protein 142;
DE   AltName: Full=SH3 domain-containing RING finger protein 1;
DE   AltName: Full=SH3 multiple domains protein 2;
GN   Name=SH3RF1; Synonyms=KIAA1494, POSH, RNF142, SH3MD2;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046328; P:regulation of JNK cascade; IEA:InterPro.
//
ID   SH3R2_HUMAN             Reviewed;         729 AA.
AC   Q8TEC5; A8K961; Q08AM9; Q6GMR9; Q8N5S8; Q96LP8;
DE   RecName: Full=Putative E3 ubiquitin-protein ligase SH3RF2;
DE            EC=6.3.2.-;
DE   AltName: Full=Heart protein phosphatase 1-binding protein;
DE            Short=HEPP1;
DE   AltName: Full=Protein phosphatase 1 regulatory subunit 39;
DE   AltName: Full=RING finger protein 158;
DE   AltName: Full=SH3 domain-containing RING finger protein 2;
GN   Name=SH3RF2; Synonyms=PPP1R39, RNF158;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008157; F:protein phosphatase 1 binding; IDA:UniProtKB.
DR   GO; GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SH3R3_HUMAN             Reviewed;         882 AA.
AC   Q8TEJ3; A0SDZ7; A8MPR1; Q8NDU1;
DE   RecName: Full=SH3 domain-containing RING finger protein 3;
DE   AltName: Full=Plenty of SH3s 2;
DE   AltName: Full=SH3 multiple domains protein 4;
GN   Name=SH3RF3; Synonyms=POSH2, SH3MD4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   SH3Y1_HUMAN             Reviewed;         342 AA.
AC   Q96HL8; A8K8E7; B7WNJ4; B7WPL6; Q8NEL2; Q9H5X4; Q9Y3V5;
DE   RecName: Full=SH3 domain-containing YSC84-like protein 1;
GN   Name=SH3YL1;
DR   GO; GO:0019902; F:phosphatase binding; IDA:MGI.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:MGI.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:Ensembl.
DR   GO; GO:1900027; P:regulation of ruffle assembly; IEA:Ensembl.
//
ID   SHAN1_HUMAN             Reviewed;        2161 AA.
AC   Q9Y566; A8MXP5; B7WNY6; Q9NYW9;
DE   RecName: Full=SH3 and multiple ankyrin repeat domains protein 1;
DE            Short=Shank1;
DE   AltName: Full=Somatostatin receptor-interacting protein;
DE            Short=SSTR-interacting protein;
DE            Short=SSTRIP;
GN   Name=SHANK1;
DR   GO; GO:0071532; F:ankyrin repeat binding; ISS:BHF-UCL.
DR   GO; GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:BHF-UCL.
DR   GO; GO:0032403; F:protein complex binding; ISS:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
DR   GO; GO:0031877; F:somatostatin receptor binding; ISS:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0008306; P:associative learning; ISS:BHF-UCL.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0050894; P:determination of affect; IMP:BHF-UCL.
DR   GO; GO:0046959; P:habituation; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; ISS:BHF-UCL.
DR   GO; GO:0032232; P:negative regulation of actin filament bundle assembly; ISS:BHF-UCL.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; ISS:BHF-UCL.
DR   GO; GO:0042048; P:olfactory behavior; IEA:Ensembl.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; ISS:BHF-UCL.
DR   GO; GO:0035418; P:protein localization to synapse; ISS:BHF-UCL.
DR   GO; GO:2000311; P:regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0060013; P:righting reflex; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0060074; P:synapse maturation; ISS:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   SHAN2_HUMAN             Reviewed;        1470 AA.
AC   Q9UPX8; C0SPG8; C0SPG9; Q3Y8G9; Q52LK2; Q9UKP1;
DE   RecName: Full=SH3 and multiple ankyrin repeat domains protein 2;
DE            Short=Shank2;
DE   AltName: Full=Cortactin-binding protein 1;
DE            Short=CortBP1;
DE   AltName: Full=Proline-rich synapse-associated protein 1;
GN   Name=SHANK2; Synonyms=CORTBP1, KIAA1022, PROSAP1;
DR   GO; GO:0030160; F:GKAP/Homer scaffold activity; NAS:UniProtKB.
DR   GO; GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0060292; P:long term synaptic depression; ISS:BHF-UCL.
DR   GO; GO:0060291; P:long-term synaptic potentiation; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   SHAN3_HUMAN             Reviewed;        1731 AA.
AC   Q9BYB0; D7UT47; Q8TET3;
DE   RecName: Full=SH3 and multiple ankyrin repeat domains protein 3;
DE            Short=Shank3;
DE   AltName: Full=Proline-rich synapse-associated protein 2;
DE            Short=ProSAP2;
GN   Name=SHANK3; Synonyms=KIAA1650, PROSAP2, PSAP2;
DR   GO; GO:0030160; F:GKAP/Homer scaffold activity; ISS:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; ISS:BHF-UCL.
DR   GO; GO:0097110; F:scaffold protein binding; ISS:BHF-UCL.
DR   GO; GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; ISS:BHF-UCL.
DR   GO; GO:0030534; P:adult behavior; IMP:BHF-UCL.
DR   GO; GO:0097113; P:alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0048854; P:brain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060997; P:dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0097117; P:guanylate kinase-associated protein clustering; ISS:BHF-UCL.
DR   GO; GO:0007612; P:learning; IMP:BHF-UCL.
DR   GO; GO:0000165; P:MAPK cascade; ISS:BHF-UCL.
DR   GO; GO:0007613; P:memory; ISS:BHF-UCL.
DR   GO; GO:0097114; P:N-methyl-D-aspartate receptor clustering; ISS:BHF-UCL.
DR   GO; GO:0032232; P:negative regulation of actin filament bundle assembly; ISS:BHF-UCL.
DR   GO; GO:0045794; P:negative regulation of cell volume; ISS:BHF-UCL.
DR   GO; GO:2000969; P:positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; ISS:BHF-UCL.
DR   GO; GO:0060999; P:positive regulation of dendritic spine development; ISS:BHF-UCL.
DR   GO; GO:2000463; P:positive regulation of excitatory postsynaptic membrane potential; ISS:BHF-UCL.
DR   GO; GO:1900451; P:positive regulation of glutamate receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0048170; P:positive regulation of long-term neuronal synaptic plasticity; ISS:BHF-UCL.
DR   GO; GO:0051835; P:positive regulation of synapse structural plasticity; ISS:BHF-UCL.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; ISS:BHF-UCL.
DR   GO; GO:0097107; P:postsynaptic density assembly; ISS:BHF-UCL.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:BHF-UCL.
DR   GO; GO:1900452; P:regulation of long term synaptic depression; ISS:BHF-UCL.
DR   GO; GO:1900271; P:regulation of long-term synaptic potentiation; ISS:BHF-UCL.
DR   GO; GO:0035176; P:social behavior; IMP:BHF-UCL.
DR   GO; GO:0021773; P:striatal medium spiny neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0007416; P:synapse assembly; ISS:BHF-UCL.
DR   GO; GO:0042297; P:vocal learning; IMP:BHF-UCL.
DR   GO; GO:0071625; P:vocalization behavior; IMP:BHF-UCL.
//
ID   SHAS3_HUMAN             Reviewed;         123 AA.
AC   Q9BTD1;
DE   RecName: Full=Putative uncharacterized protein SHANK2-AS3;
GN   Name=SHANK2-AS3; Synonyms=C11orf76;
//
ID   SHBG_HUMAN              Reviewed;         402 AA.
AC   P04278; B0FWH4; E9PGW1; F5H5Z8; I3L1N7; P14689; Q16616; Q3MIL0;
AC   Q6ISD2;
DE   RecName: Full=Sex hormone-binding globulin;
DE            Short=SHBG;
DE   AltName: Full=Sex steroid-binding protein;
DE            Short=SBP;
DE   AltName: Full=Testis-specific androgen-binding protein;
DE            Short=ABP;
DE   AltName: Full=Testosterone-estradiol-binding globulin;
DE            Short=TeBG;
DE   AltName: Full=Testosterone-estrogen-binding globulin;
DE   Flags: Precursor;
GN   Name=SHBG;
DR   GO; GO:0005497; F:androgen binding; TAS:ProtInc.
DR   GO; GO:0007285; P:primary spermatocyte growth; IEA:Ensembl.
//
ID   SHB_HUMAN               Reviewed;         509 AA.
AC   Q15464; B9EGM0; D3DRQ5; Q504U5; Q5VUM8;
DE   RecName: Full=SH2 domain-containing adapter protein B;
GN   Name=SHB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0042100; P:B cell proliferation; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:1900194; P:negative regulation of oocyte maturation; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SHC1_HUMAN              Reviewed;         583 AA.
AC   P29353; B5BU19; D3DV78; O15290; Q5T180; Q5T183; Q5T184; Q5T185;
AC   Q5T186; Q8N4K5; Q96CL1;
DE   RecName: Full=SHC-transforming protein 1;
DE   AltName: Full=SHC-transforming protein 3;
DE   AltName: Full=SHC-transforming protein A;
DE   AltName: Full=Src homology 2 domain-containing-transforming protein C1;
DE            Short=SH2 domain protein C1;
GN   Name=SHC1; Synonyms=SHC, SHCA;
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005158; F:insulin receptor binding; IPI:UniProtKB.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; TAS:UniProtKB.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0000165; P:MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; ISS:BHF-UCL.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   SHC2_HUMAN              Reviewed;         582 AA.
AC   P98077; O60230; Q9NPL5; Q9UCX4;
DE   RecName: Full=SHC-transforming protein 2;
DE   AltName: Full=Protein Sck;
DE   AltName: Full=SHC-transforming protein B;
DE   AltName: Full=Src homology 2 domain-containing-transforming protein C2;
DE            Short=SH2 domain protein C2;
GN   Name=SHC2; Synonyms=SCK, SHCB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
//
ID   SHC3_HUMAN              Reviewed;         594 AA.
AC   Q92529; Q5T7I7; Q8TAP2; Q9UCX5;
DE   RecName: Full=SHC-transforming protein 3;
DE   AltName: Full=Neuronal Shc;
DE            Short=N-Shc;
DE   AltName: Full=Protein Rai;
DE   AltName: Full=SHC-transforming protein C;
DE   AltName: Full=Src homology 2 domain-containing-transforming protein C3;
DE            Short=SH2 domain protein C3;
GN   Name=SHC3; Synonyms=NSHC, SHCC;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
//
ID   SHC4_HUMAN              Reviewed;         630 AA.
AC   Q6S5L8; Q6UXQ3; Q8IYW3;
DE   RecName: Full=SHC-transforming protein 4;
DE   AltName: Full=Rai-like protein;
DE            Short=RaLP;
DE   AltName: Full=SHC-transforming protein D;
DE            Short=hShcD;
DE   AltName: Full=Src homology 2 domain-containing-transforming protein C4;
DE            Short=SH2 domain protein C4;
GN   Name=SHC4; Synonyms=SHCD; ORFNames=UNQ6438/PRO21364;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   SHCBP_HUMAN             Reviewed;         672 AA.
AC   Q8NEM2; Q96N60; Q9BVS0; Q9H6P6;
DE   RecName: Full=SHC SH2 domain-binding protein 1;
GN   Name=SHCBP1;
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:2000177; P:regulation of neural precursor cell proliferation; ISS:UniProtKB.
//
ID   SHD_HUMAN               Reviewed;         340 AA.
AC   Q96IW2; Q96NC2;
DE   RecName: Full=SH2 domain-containing adapter protein D;
GN   Name=SHD;
//
ID   SHE_HUMAN               Reviewed;         495 AA.
AC   Q5VZ18; Q8TEQ5;
DE   RecName: Full=SH2 domain-containing adapter protein E;
GN   Name=SHE;
//
ID   SHF_HUMAN               Reviewed;         423 AA.
AC   Q7M4L6; Q96IE8;
DE   RecName: Full=SH2 domain-containing adapter protein F;
GN   Name=SHF;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   SHIP1_HUMAN             Reviewed;        1189 AA.
AC   Q92835; O00145; Q13544; Q13545; Q6P5A4; Q92656; Q9UE80;
DE   RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1;
DE            EC=3.1.3.86;
DE   AltName: Full=Inositol polyphosphate-5-phosphatase of 145 kDa;
DE            Short=SIP-145;
DE   AltName: Full=SH2 domain-containing inositol 5'-phosphatase 1;
DE            Short=SH2 domain-containing inositol phosphatase 1;
DE            Short=SHIP-1;
DE   AltName: Full=p150Ship;
DE            Short=hp51CN;
GN   Name=INPP5D; Synonyms=SHIP, SHIP1;
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.
DR   GO; GO:0034594; F:phosphatidylinositol trisphosphate phosphatase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IEA:Ensembl.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0050777; P:negative regulation of immune response; IEA:Ensembl.
DR   GO; GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045656; P:negative regulation of monocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045659; P:negative regulation of neutrophil differentiation; IEA:Ensembl.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:Ensembl.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   SHKB1_HUMAN             Reviewed;         707 AA.
AC   Q8TBC3; Q8N2I6; Q8WY93; Q96IB8;
DE   RecName: Full=SH3KBP1-binding protein 1;
GN   Name=SHKBP1; ORFNames=PP203;
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
//
ID   SHH_HUMAN               Reviewed;         462 AA.
AC   Q15465; A4D247; Q75MC9;
DE   RecName: Full=Sonic hedgehog protein;
DE            Short=SHH;
DE   AltName: Full=HHG-1;
DE   Contains:
DE     RecName: Full=Sonic hedgehog protein N-product;
DE   Contains:
DE     RecName: Full=Sonic hedgehog protein C-product;
DE   Flags: Precursor;
GN   Name=SHH;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0043237; F:laminin-1 binding; ISS:UniProtKB.
DR   GO; GO:0016015; F:morphogen activity; NAS:BHF-UCL.
DR   GO; GO:0005113; F:patched binding; IDA:BHF-UCL.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; ISS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; ISS:UniProt.
DR   GO; GO:0060840; P:artery development; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0060020; P:Bergmann glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; IEA:Ensembl.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; ISS:UniProtKB.
DR   GO; GO:0060447; P:bud outgrowth involved in lung branching; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0043369; P:CD4-positive or CD8-positive, alpha-beta T cell lineage commitment; IDA:BHF-UCL.
DR   GO; GO:0048468; P:cell development; ISS:UniProtKB.
DR   GO; GO:0001708; P:cell fate specification; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:UniProtKB.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0021930; P:cerebellar granule cell precursor proliferation; ISS:UniProtKB.
DR   GO; GO:0003140; P:determination of left/right asymmetry in lateral mesoderm; ISS:BHF-UCL.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:UniProtKB.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0009880; P:embryonic pattern specification; TAS:BHF-UCL.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; IEA:Ensembl.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0060738; P:epithelial-mesenchymal signaling involved in prostate gland development; IDA:MGI.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; ISS:UniProtKB.
DR   GO; GO:0048859; P:formation of anatomical boundary; IEA:Ensembl.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0030902; P:hindbrain development; ISS:UniProtKB.
DR   GO; GO:0007442; P:hindgut morphogenesis; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0016539; P:intein-mediated protein splicing; IEA:InterPro.
DR   GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR   GO; GO:0060459; P:left lung development; IEA:Ensembl.
DR   GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; ISS:UniProtKB.
DR   GO; GO:0060428; P:lung epithelium development; IEA:Ensembl.
DR   GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:0002320; P:lymphoid progenitor cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0030539; P:male genitalia development; ISS:UniProtKB.
DR   GO; GO:0060916; P:mesenchymal cell proliferation involved in lung development; IEA:Ensembl.
DR   GO; GO:0060783; P:mesenchymal smoothened signaling pathway involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0072136; P:metanephric mesenchymal cell proliferation involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0001656; P:metanephros development; ISS:UniProtKB.
DR   GO; GO:0030901; P:midbrain development; ISS:UniProtKB.
DR   GO; GO:0080125; P:multicellular structure septum development; IEA:Ensembl.
DR   GO; GO:0045445; P:myoblast differentiation; IEA:Ensembl.
DR   GO; GO:0014902; P:myotube differentiation; IEA:Ensembl.
DR   GO; GO:0046639; P:negative regulation of alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProt.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0090370; P:negative regulation of cholesterol efflux; ISS:BHF-UCL.
DR   GO; GO:2000357; P:negative regulation of kidney smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:2000062; P:negative regulation of ureter smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045060; P:negative thymic T cell selection; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
DR   GO; GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0048663; P:neuron fate commitment; ISS:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0048645; P:organ formation; IEA:Ensembl.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; ISS:UniProtKB.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:UniProtKB.
DR   GO; GO:0009949; P:polarity specification of anterior/posterior axis; ISS:UniProt.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060769; P:positive regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0033092; P:positive regulation of immature T cell proliferation in thymus; ISS:BHF-UCL.
DR   GO; GO:2000358; P:positive regulation of kidney smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000729; P:positive regulation of mesenchymal cell proliferation involved in ureter development; ISS:UniProtKB.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0061189; P:positive regulation of sclerotome development; IDA:BHF-UCL.
DR   GO; GO:0014858; P:positive regulation of skeletal muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0051155; P:positive regulation of striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:2000063; P:positive regulation of ureter smooth muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045059; P:positive thymic T cell selection; ISS:UniProtKB.
DR   GO; GO:0060516; P:primary prostatic bud elongation; IEA:Ensembl.
DR   GO; GO:0060523; P:prostate epithelial cord elongation; IEA:Ensembl.
DR   GO; GO:0030850; P:prostate gland development; ISS:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060782; P:regulation of mesenchymal cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:1900175; P:regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; NAS:BHF-UCL.
DR   GO; GO:0042481; P:regulation of odontogenesis; ISS:BHF-UCL.
DR   GO; GO:0060685; P:regulation of prostatic bud formation; IEA:Ensembl.
DR   GO; GO:1900180; P:regulation of protein localization to nucleus; IDA:BHF-UCL.
DR   GO; GO:0030162; P:regulation of proteolysis; ISS:UniProtKB.
DR   GO; GO:0072001; P:renal system development; IEP:UniProtKB.
DR   GO; GO:0060458; P:right lung development; IEA:Ensembl.
DR   GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEP:UniProtKB.
DR   GO; GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0061053; P:somite development; ISS:BHF-UCL.
DR   GO; GO:0021513; P:spinal cord dorsal/ventral patterning; IEA:Ensembl.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048864; P:stem cell development; ISS:UniProtKB.
DR   GO; GO:0014706; P:striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0021978; P:telencephalon regionalization; IEA:Ensembl.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; ISS:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0060439; P:trachea morphogenesis; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0007418; P:ventral midline development; TAS:BHF-UCL.
//
ID   SHIP2_HUMAN             Reviewed;        1258 AA.
AC   O15357; B2RTX5; Q13577; Q13578;
DE   RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2;
DE            EC=3.1.3.86;
DE   AltName: Full=Inositol polyphosphate phosphatase-like protein 1;
DE            Short=INPPL-1;
DE   AltName: Full=Protein 51C;
DE   AltName: Full=SH2 domain-containing inositol 5'-phosphatase 2;
DE            Short=SH2 domain-containing inositol phosphatase 2;
DE            Short=SHIP-2;
GN   Name=INPPL1; Synonyms=SHIP2;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; IMP:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0097178; P:ruffle assembly; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SHLB1_HUMAN             Reviewed;         365 AA.
AC   Q9Y371; B4E182; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9;
DE   RecName: Full=Endophilin-B1;
DE   AltName: Full=Bax-interacting factor 1;
DE            Short=Bif-1;
DE   AltName: Full=SH3 domain-containing GRB2-like protein B1;
GN   Name=SH3GLB1; Synonyms=KIAA0491; ORFNames=CGI-61;
DR   GO; GO:0005504; F:fatty acid binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0042171; F:lysophosphatidic acid acyltransferase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:HGNC.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
//
ID   SHLB2_HUMAN             Reviewed;         395 AA.
AC   Q9NR46; A6NC47; A8MPS4; Q8WY61; Q96JH9;
DE   RecName: Full=Endophilin-B2;
DE   AltName: Full=SH3 domain-containing GRB2-like protein B2;
GN   Name=SH3GLB2; Synonyms=KIAA1848; ORFNames=PP578;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SHOC2_HUMAN             Reviewed;         582 AA.
AC   Q9UQ13; A8K9W8; B3KR23; O76063; Q5VZS8; Q5VZS9;
DE   RecName: Full=Leucine-rich repeat protein SHOC-2;
DE   AltName: Full=Protein soc-2 homolog;
DE   AltName: Full=Protein sur-8 homolog;
GN   Name=SHOC2; Synonyms=KIAA0862;
DR   GO; GO:0019903; F:protein phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0019888; F:protein phosphatase regulator activity; TAS:UniProtKB.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0046579; P:positive regulation of Ras protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
//
ID   SHOT1_HUMAN             Reviewed;         631 AA.
AC   A0MZ66; A8MYU7; B3KRD3; B3KRH2; B3KTE0; B3KTJ7; B3KTJ8; B4E3U1;
AC   B7Z7Z9; Q68DG1; Q6PIM5; Q9HCH4; Q9NUV0;
DE   RecName: Full=Shootin-1;
GN   Name=KIAA1598;
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
//
ID   SHOX2_HUMAN             Reviewed;         331 AA.
AC   O60902; O60465; O60467; O60903;
DE   RecName: Full=Short stature homeobox protein 2;
DE   AltName: Full=Homeobox protein Og12X;
DE   AltName: Full=Paired-related homeobox protein SHOT;
GN   Name=SHOX2; Synonyms=OG12X, SHOT;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003209; P:cardiac atrium morphogenesis; IEA:Ensembl.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0002063; P:chondrocyte development; IEA:Ensembl.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
DR   GO; GO:0003170; P:heart valve development; IEA:Ensembl.
DR   GO; GO:0060415; P:muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0048743; P:positive regulation of skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:2000172; P:regulation of branching morphogenesis of a nerve; IEA:Ensembl.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   SHOX_HUMAN              Reviewed;         292 AA.
AC   O15266; O00412; O00413; O15267;
DE   RecName: Full=Short stature homeobox protein;
DE   AltName: Full=Pseudoautosomal homeobox-containing osteogenic protein;
DE   AltName: Full=Short stature homeobox-containing protein;
GN   Name=SHOX; Synonyms=PHOG;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   SHP1L_HUMAN             Reviewed;         725 AA.
AC   Q9BZQ2; Q4G195; Q9BZQ3; Q9H2B6;
DE   RecName: Full=SHC SH2 domain-binding protein 1-like protein;
GN   Name=SHCBP1L; Synonyms=C1orf14;
//
ID   SHPK_HUMAN              Reviewed;         478 AA.
AC   Q9UHJ6; B2R640; Q8WUH3;
DE   RecName: Full=Sedoheptulokinase;
DE            Short=SHK;
DE            EC=2.7.1.14;
DE   AltName: Full=Carbohydrate kinase-like protein;
GN   Name=SHPK; Synonyms=CARKL;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0050277; F:sedoheptulokinase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IDA:UniProtKB.
DR   GO; GO:0035963; P:cellular response to interleukin-13; ISS:UniProtKB.
DR   GO; GO:0071353; P:cellular response to interleukin-4; ISS:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; ISS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0043030; P:regulation of macrophage activation; ISS:UniProtKB.
//
ID   SHPRH_HUMAN             Reviewed;        1683 AA.
AC   Q149N8; Q149N9; Q5VV79; Q68DS5; Q7Z5J5; Q8IVE8; Q8IWQ9; Q8N1S8;
AC   Q8NBR7;
DE   RecName: Full=E3 ubiquitin-protein ligase SHPRH;
DE            EC=3.6.4.-;
DE            EC=6.3.2.-;
DE   AltName: Full=SNF2, histone-linker, PHD and RING finger domain-containing helicase;
GN   Name=SHPRH; Synonyms=KIAA2023;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SHPS1_HUMAN             Reviewed;         504 AA.
AC   P78324; A2A2E1; A8K411; B2R6C3; O00683; O43799; Q8N517; Q8TAL8;
AC   Q9H0Z2; Q9UDX2; Q9UIJ6; Q9Y4U9;
DE   RecName: Full=Tyrosine-protein phosphatase non-receptor type substrate 1;
DE            Short=SHP substrate 1;
DE            Short=SHPS-1;
DE   AltName: Full=Brain Ig-like molecule with tyrosine-based activation motifs;
DE            Short=Bit;
DE   AltName: Full=CD172 antigen-like family member A;
DE   AltName: Full=Inhibitory receptor SHPS-1;
DE   AltName: Full=Macrophage fusion receptor;
DE   AltName: Full=MyD-1 antigen;
DE   AltName: Full=Signal-regulatory protein alpha-1;
DE            Short=Sirp-alpha-1;
DE   AltName: Full=Signal-regulatory protein alpha-2;
DE            Short=Sirp-alpha-2;
DE   AltName: Full=Signal-regulatory protein alpha-3;
DE            Short=Sirp-alpha-3;
DE   AltName: Full=p84;
DE   AltName: CD_antigen=CD172a;
DE   Flags: Precursor;
GN   Name=SIRPA; Synonyms=BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
//
ID   SHQ1_HUMAN              Reviewed;         577 AA.
AC   Q6PI26; Q6MZJ4; Q7Z748; Q9H7E5; Q9NVS8;
DE   RecName: Full=Protein SHQ1 homolog;
GN   Name=SHQ1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:2000233; P:negative regulation of rRNA processing; IDA:MGI.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:MGI.
DR   GO; GO:0022618; P:ribonucleoprotein complex assembly; IDA:UniProtKB.
//
ID   SHRM1_HUMAN             Reviewed;         852 AA.
AC   Q2M3G4; B7WP40; B7ZL01; Q8TDP0; Q8TF41;
DE   RecName: Full=Protein Shroom1;
DE   AltName: Full=Apical protein 2;
GN   Name=SHROOM1; Synonyms=APXL2, KIAA1960;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0051017; P:actin filament bundle assembly; ISS:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; ISS:UniProtKB.
//
ID   SHRM2_HUMAN             Reviewed;        1616 AA.
AC   Q13796; B9EIQ7;
DE   RecName: Full=Protein Shroom2;
DE   AltName: Full=Apical-like protein;
DE   AltName: Full=Protein APXL;
GN   Name=SHROOM2; Synonyms=APXL;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; ISS:UniProtKB.
DR   GO; GO:0015280; F:ligand-gated sodium channel activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045176; P:apical protein localization; ISS:HGNC.
DR   GO; GO:0007420; P:brain development; ISS:HGNC.
DR   GO; GO:0043010; P:camera-type eye development; ISS:HGNC.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; ISS:HGNC.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0045217; P:cell-cell junction maintenance; IEA:Ensembl.
DR   GO; GO:0043482; P:cellular pigment accumulation; ISS:HGNC.
DR   GO; GO:0043583; P:ear development; ISS:HGNC.
DR   GO; GO:0032401; P:establishment of melanosome localization; ISS:HGNC.
DR   GO; GO:0008057; P:eye pigment granule organization; ISS:HGNC.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; ISS:HGNC.
DR   GO; GO:0032438; P:melanosome organization; ISS:HGNC.
DR   GO; GO:0030835; P:negative regulation of actin filament depolymerization; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
//
ID   SHRM3_HUMAN             Reviewed;        1996 AA.
AC   Q8TF72; Q5QTQ3; Q6ZRW3; Q96IR9; Q9P247;
DE   RecName: Full=Protein Shroom3;
DE   AltName: Full=Shroom-related protein;
DE            Short=hShrmL;
GN   Name=SHROOM3; Synonyms=KIAA1481, SHRML; ORFNames=MSTP013;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0045176; P:apical protein localization; ISS:HGNC.
DR   GO; GO:0000902; P:cell morphogenesis; ISS:HGNC.
DR   GO; GO:0043482; P:cellular pigment accumulation; ISS:HGNC.
DR   GO; GO:0002066; P:columnar/cuboidal epithelial cell development; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; ISS:HGNC.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
//
ID   SHRM4_HUMAN             Reviewed;        1493 AA.
AC   Q9ULL8; A7E2X9; D6RFW0; Q96LA0;
DE   RecName: Full=Protein Shroom4;
DE   AltName: Full=Second homolog of apical protein;
GN   Name=SHROOM4; Synonyms=KIAA1202, SHAP;
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0007015; P:actin filament organization; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IDA:UniProtKB.
DR   GO; GO:0050890; P:cognition; IDA:UniProtKB.
//
ID   SHRPN_HUMAN             Reviewed;         387 AA.
AC   Q9H0F6; A6NEG3; C0L3L2; D3DWL3; Q8IXF5; Q8IXF6; Q8N2E7; Q8TB25;
AC   Q9BUE4;
DE   RecName: Full=Sharpin;
DE   AltName: Full=Shank-associated RH domain-interacting protein;
DE   AltName: Full=Shank-interacting protein-like 1;
DE            Short=hSIPL1;
GN   Name=SHARPIN; Synonyms=SIPL1; ORFNames=PSEC0216;
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030262; P:apoptotic nuclear changes; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0031424; P:keratinization; IEA:Ensembl.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.
DR   GO; GO:2000348; P:regulation of CD40 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010803; P:regulation of tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
//
ID   SHSA2_HUMAN             Reviewed;         295 AA.
AC   Q6UWI4; B9EH70; Q5W0G8;
DE   RecName: Full=Protein shisa-2 homolog;
DE   AltName: Full=Transmembrane protein 46;
DE   Flags: Precursor;
GN   Name=SHISA2; Synonyms=C13orf13, TMEM46; ORFNames=UNQ9166/PRO28631;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   SHSA3_HUMAN             Reviewed;         238 AA.
AC   A0PJX4; A0PJX3; Q96EQ5;
DE   RecName: Full=Protein shisa-3 homolog;
DE   Flags: Precursor;
GN   Name=SHISA3;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   SHSA5_HUMAN             Reviewed;         240 AA.
AC   Q8N114; B3KW99; Q69YY9; Q7Z433; Q8NHL9; Q96MW8; Q9BV58;
DE   RecName: Full=Protein shisa-5;
DE   AltName: Full=Putative NF-kappa-B-activating protein 120;
DE   AltName: Full=Scotin;
DE   Flags: Precursor;
GN   Name=SHISA5; Synonyms=SCOTIN; ORFNames=PSEC0133;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
//
ID   SHSA4_HUMAN             Reviewed;         197 AA.
AC   Q96DD7; B4DFI0; B7ZAJ7; Q5VUU1; Q6P711; Q6UWY7;
DE   RecName: Full=Protein shisa-4;
DE   AltName: Full=Transmembrane protein 58;
DE   Flags: Precursor;
GN   Name=SHISA4; Synonyms=C1orf40, TMEM58; ORFNames=UNQ583/PRO1153;
//
ID   SHSA6_HUMAN             Reviewed;         500 AA.
AC   Q6ZSJ9; B3KXV5; Q4PL63;
DE   RecName: Full=Protein shisa-6 homolog;
DE   Flags: Precursor;
GN   Name=SHISA6;
//
ID   SHSA7_HUMAN             Reviewed;         538 AA.
AC   A6NL88;
DE   RecName: Full=Protein shisa-7;
DE   AltName: Full=Protein shisa-6-like;
DE   Flags: Precursor;
GN   Name=SHISA7;
//
ID   SHSA8_HUMAN             Reviewed;         492 AA.
AC   B8ZZ34;
DE   RecName: Full=Putative protein shisa-8;
DE   Flags: Precursor;
GN   Name=SHISA8; Synonyms=C22orf17;
//
ID   SHSA9_HUMAN             Reviewed;         424 AA.
AC   B4DS77; C9J314; C9JCE9;
DE   RecName: Full=Protein shisa-9;
DE   Flags: Precursor;
GN   Name=SHISA9;
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; ISS:UniProtKB.
//
ID   SI11L_HUMAN             Reviewed;          58 AA.
AC   Q5T5W8;
DE   RecName: Full=Putative small integral membrane protein 11-like;
DE   AltName: Full=Small integral membrane protein 11 pseudogene 1;
GN   Name=SMIM11P1; Synonyms=C6orf161, FAM165A;
//
ID   SI1L1_HUMAN             Reviewed;        1804 AA.
AC   O43166; J3KP19; O95321; Q9UDU4; Q9UNU4;
DE   RecName: Full=Signal-induced proliferation-associated 1-like protein 1;
DE            Short=SIPA1-like protein 1;
DE   AltName: Full=High-risk human papilloma viruses E6 oncoproteins targeted protein 1;
DE            Short=E6-targeted protein 1;
GN   Name=SIPA1L1; Synonyms=E6TP1, KIAA0440;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.
DR   GO; GO:0032861; P:activation of Rap GTPase activity; ISS:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.
DR   GO; GO:0032317; P:regulation of Rap GTPase activity; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
//
ID   SI1L2_HUMAN             Reviewed;        1722 AA.
AC   Q9P2F8; Q2TV88; Q5VXR7; Q5VXR8; Q641Q4; Q8NA38; Q96DZ3; Q9H9F6;
DE   RecName: Full=Signal-induced proliferation-associated 1-like protein 2;
DE            Short=SIPA1-like protein 2;
GN   Name=SIPA1L2; Synonyms=KIAA1389;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   SI1L3_HUMAN             Reviewed;        1781 AA.
AC   O60292; Q2TV87;
DE   RecName: Full=Signal-induced proliferation-associated 1-like protein 3;
DE            Short=SIPA1-like protein 3;
DE   AltName: Full=SPA-1-like protein 3;
GN   Name=SIPA1L3; Synonyms=KIAA0545, SPAL3;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
//
ID   SIA10_HUMAN             Reviewed;         331 AA.
AC   Q9Y274; B2RCH2; B3KMI1; D3DN39; F8W6U0;
DE   RecName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase;
DE            EC=2.4.99.-;
DE   AltName: Full=CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI;
DE   AltName: Full=ST3Gal VI;
DE            Short=ST3GalVI;
DE   AltName: Full=Sialyltransferase 10;
GN   Name=ST3GAL6; Synonyms=SIAT10;
DR   GO; GO:0052798; F:beta-galactoside alpha-2,3-sialyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:UniProtKB.
DR   GO; GO:0071354; P:cellular response to interleukin-6; IEP:UniProtKB.
DR   GO; GO:0006664; P:glycolipid metabolic process; IDA:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IDA:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SIA4A_HUMAN             Reviewed;         340 AA.
AC   Q11201; O60677; Q9UN51;
DE   RecName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1;
DE            Short=Alpha 2,3-ST 1;
DE            Short=Beta-galactoside alpha-2,3-sialyltransferase 1;
DE            EC=2.4.99.4;
DE   AltName: Full=Gal-NAc6S;
DE   AltName: Full=Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase;
DE   AltName: Full=SIATFL;
DE   AltName: Full=ST3Gal I;
DE            Short=ST3GalI;
DE   AltName: Full=ST3GalA.1;
DE   AltName: Full=ST3O;
DE   AltName: Full=Sialyltransferase 4A;
DE            Short=SIAT4-A;
GN   Name=ST3GAL1; Synonyms=SIAT4, SIAT4A;
DR   GO; GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006054; P:N-acetylneuraminate metabolic process; ISS:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0097503; P:sialylation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SIA4B_HUMAN             Reviewed;         350 AA.
AC   Q16842; O00654;
DE   RecName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2;
DE            Short=Alpha 2,3-ST 2;
DE            Short=Beta-galactoside alpha-2,3-sialyltransferase 2;
DE            EC=2.4.99.4;
DE   AltName: Full=Gal-NAc6S;
DE   AltName: Full=Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase;
DE   AltName: Full=ST3Gal II;
DE            Short=ST3GalII;
DE   AltName: Full=ST3GalA.2;
DE   AltName: Full=Sialyltransferase 4B;
DE            Short=SIAT4-B;
GN   Name=ST3GAL2; Synonyms=SIAT4B;
DR   GO; GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006040; P:amino sugar metabolic process; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0097503; P:sialylation; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SIA4C_HUMAN             Reviewed;         333 AA.
AC   Q11206; A8K6B2; O60497; Q8N6A6; Q8NFG7; Q96QQ9;
DE   RecName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4;
DE            Short=Alpha 2,3-ST 4;
DE            Short=Beta-galactoside alpha-2,3-sialyltransferase 4;
DE            EC=2.4.99.-;
DE   AltName: Full=Alpha 2,3-sialyltransferase IV;
DE   AltName: Full=Gal-NAc6S;
DE   AltName: Full=Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase;
DE   AltName: Full=SAT-3;
DE   AltName: Full=ST-4;
DE   AltName: Full=ST3Gal IV;
DE            Short=ST3GalIV;
DE   AltName: Full=ST3GalA.2;
DE   AltName: Full=STZ;
DE   AltName: Full=Sialyltransferase 4C;
DE            Short=SIAT4-C;
GN   Name=ST3GAL4; Synonyms=CGS23, NANTA3, SIAT4C, STZ;
DR   GO; GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0047288; F:monosialoganglioside sialyltransferase activity; IEA:Ensembl.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0097503; P:sialylation; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SIA7A_HUMAN             Reviewed;         600 AA.
AC   Q9NSC7; Q6UW90; Q9NSC6;
DE   RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1;
DE            EC=2.4.99.3;
DE   AltName: Full=GalNAc alpha-2,6-sialyltransferase I;
DE   AltName: Full=ST6GalNAc I;
DE            Short=ST6GalNAcI;
DE   AltName: Full=Sialyltransferase 7A;
DE            Short=SIAT7-A;
GN   Name=ST6GALNAC1; Synonyms=SIAT7A; ORFNames=UNQ543/PRO848;
DR   GO; GO:0001665; F:alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008373; F:sialyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; NAS:UniProtKB.
DR   GO; GO:0097503; P:sialylation; NAS:GOC.
//
ID   SIA7B_HUMAN             Reviewed;         374 AA.
AC   Q9UJ37; Q12971;
DE   RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2;
DE            EC=2.4.99.-;
DE   AltName: Full=GalNAc alpha-2,6-sialyltransferase II;
DE   AltName: Full=ST6GalNAc II;
DE            Short=ST6GalNAcII;
DE   AltName: Full=SThM;
DE   AltName: Full=Sialyltransferase 7B;
DE            Short=SIAT7-B;
GN   Name=ST6GALNAC2; Synonyms=SIAT7B, SIATL1, STHM;
DR   GO; GO:0008373; F:sialyltransferase activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   SIA7C_HUMAN             Reviewed;         305 AA.
AC   Q8NDV1; Q6PCE0; Q6UX29; Q8N259;
DE   RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3;
DE            EC=2.4.99.-;
DE   AltName: Full=GalNAc alpha-2,6-sialyltransferase III;
DE   AltName: Full=ST6GalNAc III;
DE            Short=ST6GalNAcIII;
DE   AltName: Full=STY;
DE   AltName: Full=Sialyltransferase 7C;
DE            Short=SIAT7-C;
GN   Name=ST6GALNAC3; Synonyms=SIAT7C; ORFNames=UNQ2787/PRO7177;
DR   GO; GO:0008373; F:sialyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006677; P:glycosylceramide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIA7D_HUMAN             Reviewed;         302 AA.
AC   Q9H4F1; Q5T9D0; Q9NWU6; Q9UKU1; Q9ULB9; Q9Y3G3; Q9Y3G4;
DE   RecName: Full=Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase;
DE            EC=2.4.99.7;
DE   AltName: Full=NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase;
DE   AltName: Full=ST6GalNAc IV;
DE            Short=ST6GalNAcIV;
DE   AltName: Full=Sialyltransferase 3C;
DE            Short=SIAT3-C;
DE   AltName: Full=Sialyltransferase 7D;
DE            Short=SIAT7-D;
GN   Name=ST6GALNAC4; Synonyms=SIAT3C, SIAT7D;
DR   GO; GO:0047290; F:(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008373; F:sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006664; P:glycolipid metabolic process; TAS:ProtInc.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0097503; P:sialylation; TAS:GOC.
//
ID   SIA7E_HUMAN             Reviewed;         336 AA.
AC   Q9BVH7; B1AK82;
DE   RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5;
DE            EC=2.4.99.-;
DE   AltName: Full=GD1 alpha synthase;
DE   AltName: Full=GalNAc alpha-2,6-sialyltransferase V;
DE   AltName: Full=ST6GalNAc V;
DE            Short=ST6GalNAcV;
DE   AltName: Full=Sialyltransferase 7E;
DE            Short=SIAT7-E;
GN   Name=ST6GALNAC5; Synonyms=SIAT7E;
DR   GO; GO:0001665; F:alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity; ISS:BHF-UCL.
DR   GO; GO:0008373; F:sialyltransferase activity; ISS:BHF-UCL.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0097503; P:sialylation; ISS:GOC.
//
ID   SIA7F_HUMAN             Reviewed;         333 AA.
AC   Q969X2; B3KQ01; Q5T9C4; Q5T9C5; Q9H8A2; Q9ULB8;
DE   RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6;
DE            EC=2.4.99.-;
DE   AltName: Full=GalNAc alpha-2,6-sialyltransferase VI;
DE   AltName: Full=ST6GalNAc VI;
DE            Short=ST6GalNAcVI;
DE            Short=hST6GalNAc VI;
DE   AltName: Full=Sialyltransferase 7F;
DE            Short=SIAT7-F;
GN   Name=ST6GALNAC6; Synonyms=SIAT7F; ORFNames=UNQ708/PRO1359;
DR   GO; GO:0001665; F:alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity; ISS:BHF-UCL.
DR   GO; GO:0008373; F:sialyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0009988; P:cell-cell recognition; IC:BHF-UCL.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006677; P:glycosylceramide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0009312; P:oligosaccharide biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIA8A_HUMAN             Reviewed;         356 AA.
AC   Q92185; A8K4H6; Q17RL0; Q6PZN5; Q93064;
DE   RecName: Full=Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase;
DE            EC=2.4.99.8;
DE   AltName: Full=Alpha-2,8-sialyltransferase 8A;
DE   AltName: Full=Ganglioside GD3 synthase;
DE   AltName: Full=Ganglioside GT3 synthase;
DE   AltName: Full=Sialyltransferase 8A;
DE            Short=SIAT8-A;
DE   AltName: Full=Sialyltransferase St8Sia I;
DE            Short=ST8SiaI;
GN   Name=ST8SIA1; Synonyms=SIAT8, SIAT8A;
DR   GO; GO:0003828; F:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008373; F:sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0097503; P:sialylation; TAS:GOC.
//
ID   SIA8B_HUMAN             Reviewed;         375 AA.
AC   Q92186; Q4VAZ0; Q92470; Q92746;
DE   RecName: Full=Alpha-2,8-sialyltransferase 8B;
DE            EC=2.4.99.-;
DE   AltName: Full=Sialyltransferase 8B;
DE            Short=SIAT8-B;
DE   AltName: Full=Sialyltransferase St8Sia II;
DE            Short=ST8SiaII;
DE   AltName: Full=Sialyltransferase X;
DE            Short=STX;
GN   Name=ST8SIA2; Synonyms=SIAT8B, STX;
DR   GO; GO:0003828; F:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0033691; F:sialic acid binding; IC:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006491; P:N-glycan processing; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; IDA:BHF-UCL.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIA8C_HUMAN             Reviewed;         380 AA.
AC   O43173; A8K0F2; Q6B085; Q9NS41;
DE   RecName: Full=Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase;
DE            EC=2.4.99.-;
DE   AltName: Full=Alpha-2,8-sialyltransferase 8C;
DE   AltName: Full=Alpha-2,8-sialyltransferase III;
DE   AltName: Full=ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3;
DE   AltName: Full=Sialyltransferase 8C;
DE            Short=SIAT8-C;
DE   AltName: Full=Sialyltransferase St8Sia III;
DE            Short=ST8SiaIII;
GN   Name=ST8SIA3; Synonyms=SIAT8C;
DR   GO; GO:0003828; F:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0033691; F:sialic acid binding; IC:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006491; P:N-glycan processing; IDA:BHF-UCL.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006486; P:protein glycosylation; IDA:BHF-UCL.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIA8D_HUMAN             Reviewed;         359 AA.
AC   Q92187; A8KA07; G3V104; Q8N1F4; Q92693;
DE   RecName: Full=CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase;
DE            EC=2.4.99.-;
DE   AltName: Full=Alpha-2,8-sialyltransferase 8D;
DE   AltName: Full=Polysialyltransferase-1;
DE   AltName: Full=Sialyltransferase 8D;
DE            Short=SIAT8-D;
DE   AltName: Full=Sialyltransferase St8Sia IV;
DE            Short=ST8SiaIV;
GN   Name=ST8SIA4; Synonyms=PST, PST1, SIAT8D;
DR   GO; GO:0003828; F:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0033691; F:sialic acid binding; IC:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006491; P:N-glycan processing; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006486; P:protein glycosylation; IDA:BHF-UCL.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIA8E_HUMAN             Reviewed;         376 AA.
AC   O15466; Q6IAW7;
DE   RecName: Full=Alpha-2,8-sialyltransferase 8E;
DE            EC=2.4.99.-;
DE   AltName: Full=Sialyltransferase 8E;
DE            Short=SIAT8-E;
DE   AltName: Full=Sialyltransferase St8Sia V;
DE            Short=ST8SiaV;
GN   Name=ST8SIA5; Synonyms=SIAT8E;
DR   GO; GO:0003828; F:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; IEA:Ensembl.
DR   GO; GO:0008373; F:sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0097503; P:sialylation; TAS:GOC.
//
ID   SIA8F_HUMAN             Reviewed;         398 AA.
AC   P61647; B0YJ97; B9EH72; Q5VZH4;
DE   RecName: Full=Alpha-2,8-sialyltransferase 8F;
DE            EC=2.4.99.-;
DE   AltName: Full=Sialyltransferase 8F;
DE            Short=SIAT8-F;
DE   AltName: Full=Sialyltransferase St8Sia VI;
DE            Short=ST8SiaVI;
GN   Name=ST8SIA6; Synonyms=SIAT8F;
DR   GO; GO:0008373; F:sialyltransferase activity; ISS:BHF-UCL.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0009247; P:glycolipid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0009100; P:glycoprotein metabolic process; ISS:BHF-UCL.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; ISS:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006493; P:protein O-linked glycosylation; ISS:BHF-UCL.
DR   GO; GO:0097503; P:sialylation; ISS:GOC.
//
ID   SIAE_HUMAN              Reviewed;         523 AA.
AC   Q9HAT2; B3KPB0; Q8IUT9; Q9HAU7; Q9NT71;
DE   RecName: Full=Sialate O-acetylesterase;
DE            EC=3.1.1.53;
DE   AltName: Full=H-Lse;
DE   AltName: Full=Sialic acid-specific 9-O-acetylesterase;
DE   Flags: Precursor;
GN   Name=SIAE; Synonyms=YSG2;
DR   GO; GO:0001681; F:sialate O-acetylesterase activity; IDA:UniProt.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IDA:UniProt.
DR   GO; GO:0002682; P:regulation of immune system process; IMP:UniProt.
//
ID   SIAH1_HUMAN             Reviewed;         282 AA.
AC   Q8IUQ4; A0FKF3; O43269; Q49A58; Q92880;
DE   RecName: Full=E3 ubiquitin-protein ligase SIAH1;
DE            EC=6.3.2.-;
DE   AltName: Full=Seven in absentia homolog 1;
DE            Short=Siah-1;
DE   AltName: Full=Siah-1a;
GN   Name=SIAH1; Synonyms=HUMSIAH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0051402; P:neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001244; P:positive regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IEA:Ensembl.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
//
ID   SIAH2_HUMAN             Reviewed;         324 AA.
AC   O43255; O43270;
DE   RecName: Full=E3 ubiquitin-protein ligase SIAH2;
DE            EC=6.3.2.-;
DE   AltName: Full=Seven in absentia homolog 2;
DE            Short=Siah-2;
DE            Short=hSiah2;
GN   Name=SIAH2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0044257; P:cellular protein catabolic process; IGI:MGI.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IGI:MGI.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   SIAH3_HUMAN             Reviewed;         269 AA.
AC   Q8IW03; B7ZBP0; Q8N8M6;
DE   RecName: Full=Seven in absentia homolog 3;
DE            Short=Siah-3;
GN   Name=SIAH3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   SIAL_HUMAN              Reviewed;         317 AA.
AC   P21815;
DE   RecName: Full=Bone sialoprotein 2;
DE   AltName: Full=Bone sialoprotein II;
DE            Short=BSP II;
DE   AltName: Full=Cell-binding sialoprotein;
DE   AltName: Full=Integrin-binding sialoprotein;
DE   Flags: Precursor;
GN   Name=IBSP; Synonyms=BNSP;
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IEA:InterPro.
//
ID   SIAS_HUMAN              Reviewed;         359 AA.
AC   Q9NR45; B2RE98; Q8WUV9; Q9BWS6; Q9NVD4;
DE   RecName: Full=Sialic acid synthase;
DE   AltName: Full=N-acetylneuraminate synthase;
DE            EC=2.5.1.56;
DE   AltName: Full=N-acetylneuraminate-9-phosphate synthase;
DE            EC=2.5.1.57;
DE   AltName: Full=N-acetylneuraminic acid phosphate synthase;
DE   AltName: Full=N-acetylneuraminic acid synthase;
GN   Name=NANS; Synonyms=SAS;
DR   GO; GO:0050462; F:N-acetylneuraminate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008781; F:N-acylneuraminate cytidylyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0047444; F:N-acylneuraminate-9-phosphate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; NAS:UniProtKB.
//
ID   SIAT1_HUMAN             Reviewed;         406 AA.
AC   P15907; A8KA14; D3DNV3;
DE   RecName: Full=Beta-galactoside alpha-2,6-sialyltransferase 1;
DE            Short=Alpha 2,6-ST 1;
DE            EC=2.4.99.1;
DE   AltName: Full=B-cell antigen CD75;
DE   AltName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1;
DE   AltName: Full=ST6Gal I;
DE            Short=ST6GalI;
DE   AltName: Full=Sialyltransferase 1;
GN   Name=ST6GAL1; Synonyms=SIAT1;
DR   GO; GO:0003835; F:beta-galactoside alpha-2,6-sialyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008373; F:sialyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0006054; P:N-acetylneuraminate metabolic process; IDA:UniProtKB.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IDA:UniProtKB.
DR   GO; GO:0097503; P:sialylation; IDA:UniProtKB.
//
ID   SIAT2_HUMAN             Reviewed;         529 AA.
AC   Q96JF0; D3DVK3; Q53QP4; Q86Y44; Q8IUG7; Q96HE4;
DE   RecName: Full=Beta-galactoside alpha-2,6-sialyltransferase 2;
DE            Short=Alpha 2,6-ST 2;
DE            EC=2.4.99.1;
DE   AltName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2;
DE   AltName: Full=ST6Gal II;
DE            Short=ST6GalII;
DE            Short=hST6Gal II;
DE   AltName: Full=Sialyltransferase 2;
GN   Name=ST6GAL2; Synonyms=KIAA1877, SIAT2;
DR   GO; GO:0003835; F:beta-galactoside alpha-2,6-sialyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0040007; P:growth; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0009311; P:oligosaccharide metabolic process; IDA:UniProtKB.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIAT6_HUMAN             Reviewed;         375 AA.
AC   Q11203; A9Z1W2; D3DPX8; Q5T4W9; Q5T4X0; Q5T4X7; Q5T4X8; Q5T4X9;
AC   Q5T4Y0; Q5T4Y2; Q5T4Y3; Q5T4Y4; Q86UR6; Q86UR7; Q86UR8; Q86UR9;
AC   Q86US0; Q86US1; Q86US2; Q8IX41; Q8IX42; Q8IX43; Q8IX44; Q8IX45;
AC   Q8IX46; Q8IX47; Q8IX48; Q8IX49; Q8IX50; Q8IX51; Q8IX52; Q8IX53;
AC   Q8IX54; Q8IX55; Q8IX56; Q8IX57; Q8IX58;
DE   RecName: Full=CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase;
DE            EC=2.4.99.6;
DE   AltName: Full=Beta-galactoside alpha-2,3-sialyltransferase 3;
DE            Short=Alpha 2,3-ST 3;
DE   AltName: Full=Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase;
DE   AltName: Full=N-acetyllactosaminide alpha-2,3-sialyltransferase;
DE   AltName: Full=ST3Gal III;
DE            Short=ST3GalIII;
DE   AltName: Full=ST3N;
DE   AltName: Full=Sialyltransferase 6;
GN   Name=ST3GAL3; Synonyms=SIAT6;
DR   GO; GO:0003836; F:beta-galactoside (CMP) alpha-2,3-sialyltransferase activity; IEA:Ensembl.
DR   GO; GO:0008118; F:N-acetyllactosaminide alpha-2,3-sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0018146; P:keratan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0042339; P:keratan sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0016266; P:O-glycan processing; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0097503; P:sialylation; TAS:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SIAT9_HUMAN             Reviewed;         418 AA.
AC   Q9UNP4; B3KM82; D6W5L9; O94902; Q53QU1; Q6NZX4; Q6YFL1;
DE   RecName: Full=Lactosylceramide alpha-2,3-sialyltransferase;
DE            EC=2.4.99.9;
DE   AltName: Full=CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase;
DE   AltName: Full=Ganglioside GM3 synthase;
DE   AltName: Full=ST3Gal V;
DE            Short=ST3GalV;
DE   AltName: Full=Sialyltransferase 9;
GN   Name=ST3GAL5; Synonyms=SIAT9; ORFNames=UNQ2510/PRO5998;
DR   GO; GO:0047291; F:lactosylceramide alpha-2,3-sialyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004513; F:neolactotetraosylceramide alpha-2,3-sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0008373; F:sialyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0001574; P:ganglioside biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   GO; GO:0097503; P:sialylation; IDA:GOC.
//
ID   SIDT1_HUMAN             Reviewed;         827 AA.
AC   Q9NXL6; Q17RR4;
DE   RecName: Full=SID1 transmembrane family member 1;
DE   Flags: Precursor;
GN   Name=SIDT1;
DR   GO; GO:0051033; F:RNA transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0033227; P:dsRNA transport; IEA:InterPro.
//
ID   SIDT2_HUMAN             Reviewed;         832 AA.
AC   Q8NBJ9; Q8NBY7; Q9Y357;
DE   RecName: Full=SID1 transmembrane family member 2;
DE   Flags: Precursor;
GN   Name=SIDT2; ORFNames=CGI-40, PSEC0072, UNQ685/PRO1325;
DR   GO; GO:0051033; F:RNA transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0033227; P:dsRNA transport; IEA:InterPro.
//
ID   SIG10_HUMAN             Reviewed;         697 AA.
AC   Q96LC7; A8K1I5; A8K3C7; C9JJ33; C9JM10; F8W917; Q3MIR5; Q6UXI8;
AC   Q96G54; Q96LC8;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 10;
DE            Short=Siglec-10;
DE   AltName: Full=Siglec-like protein 2;
DE   Flags: Precursor;
GN   Name=SIGLEC10; Synonyms=SLG2; ORFNames=UNQ477/PRO940;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SIG11_HUMAN             Reviewed;         698 AA.
AC   Q96RL6;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 11;
DE            Short=Sialic acid-binding lectin 11;
DE            Short=Siglec-11;
DE   Flags: Precursor;
GN   Name=SIGLEC11; ORFNames=UNQ9222/PRO28718;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SIG12_HUMAN             Reviewed;         595 AA.
AC   Q96PQ1; Q8IYH7;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 12;
DE            Short=Siglec-12;
DE   AltName: Full=Sialic acid-binding Ig-like lectin-like 1;
DE            Short=Siglec-L1;
DE   Flags: Precursor;
GN   Name=SIGLEC12; Synonyms=SIGLECL1, SLG; ORFNames=UNQ9215/PRO34042;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SIG14_HUMAN             Reviewed;         396 AA.
AC   Q08ET2; Q6UXG0;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 14;
DE            Short=Siglec-14;
DE   Flags: Precursor;
GN   Name=SIGLEC14; ORFNames=UNQ294/PRO333;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   SIG15_HUMAN             Reviewed;         328 AA.
AC   Q6ZMC9; A8K2Y5;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 15;
DE            Short=Siglec-15;
DE   AltName: Full=CD33 antigen-like 3;
DE   Flags: Precursor;
GN   Name=SIGLEC15; Synonyms=CD33L3;
DR   GO; GO:0071402; P:cellular response to lipoprotein particle stimulus; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0045124; P:regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:2001204; P:regulation of osteoclast development; IEA:Ensembl.
//
ID   SIG16_HUMAN             Reviewed;         481 AA.
AC   A6NMB1;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 16;
DE            Short=Siglec-16;
DE   AltName: Full=Siglec-P16;
DE   Flags: Precursor;
GN   Name=SIGLEC16; Synonyms=SIGLECP16;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   SIGIR_HUMAN             Reviewed;         410 AA.
AC   Q6IA17; Q3KQY2; Q6UXI3; Q9H733;
DE   RecName: Full=Single Ig IL-1-related receptor;
DE   AltName: Full=Single Ig IL-1R-related molecule;
DE   AltName: Full=Single immunoglobulin domain-containing IL1R-related protein;
DE   AltName: Full=Toll/interleukin-1 receptor 8;
DE            Short=TIR8;
GN   Name=SIGIRR; ORFNames=UNQ301/PRO342;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; ISS:HGNC.
DR   GO; GO:0045079; P:negative regulation of chemokine biosynthetic process; ISS:HGNC.
DR   GO; GO:0001960; P:negative regulation of cytokine-mediated signaling pathway; ISS:HGNC.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; TAS:HGNC.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:HGNC.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SIGL1_HUMAN             Reviewed;         197 AA.
AC   Q8N7X8;
DE   RecName: Full=SIGLEC family-like protein 1;
GN   Name=SIGLECL1; Synonyms=C19orf75;
//
ID   SIGL5_HUMAN             Reviewed;         551 AA.
AC   O15389;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 5;
DE            Short=Siglec-5;
DE   AltName: Full=CD33 antigen-like 2;
DE   AltName: Full=Obesity-binding protein 2;
DE            Short=OB-BP2;
DE            Short=OB-binding protein 2;
DE   AltName: CD_antigen=CD170;
DE   Flags: Precursor;
GN   Name=SIGLEC5; Synonyms=CD33L2, OBBP2;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SIGL6_HUMAN             Reviewed;         453 AA.
AC   O43699; A8MV71; B2RTS8; C9JBE5; F8WA78; O15388; O43700;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 6;
DE            Short=Siglec-6;
DE   AltName: Full=CD33 antigen-like 1;
DE   AltName: Full=CDw327;
DE   AltName: Full=Obesity-binding protein 1;
DE            Short=OB-BP1;
DE   AltName: CD_antigen=CD327;
DE   Flags: Precursor;
GN   Name=SIGLEC6; Synonyms=CD33L, CD33L1, OBBP1;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
//
ID   SIGL7_HUMAN             Reviewed;         467 AA.
AC   Q9Y286; Q9NZQ1; Q9UJ86; Q9UJ87; Q9Y502;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 7;
DE            Short=Siglec-7;
DE   AltName: Full=Adhesion inhibitory receptor molecule 1;
DE            Short=AIRM-1;
DE   AltName: Full=CDw328;
DE   AltName: Full=D-siglec;
DE   AltName: Full=QA79 membrane protein;
DE   AltName: Full=p75;
DE   AltName: CD_antigen=CD328;
DE   Flags: Precursor;
GN   Name=SIGLEC7; Synonyms=AIRM1;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SIGL8_HUMAN             Reviewed;         499 AA.
AC   Q9NYZ4; Q7Z728;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 8;
DE            Short=Siglec-8;
DE   AltName: Full=Sialoadhesin family member 2;
DE            Short=SAF-2;
DE   Flags: Precursor;
GN   Name=SIGLEC8; Synonyms=SAF2;
DR   GO; GO:0030246; F:carbohydrate binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SIGL9_HUMAN             Reviewed;         463 AA.
AC   Q9Y336; Q6GTU4; Q9BYI9;
DE   RecName: Full=Sialic acid-binding Ig-like lectin 9;
DE            Short=Siglec-9;
DE   AltName: Full=CDw329;
DE   AltName: Full=Protein FOAP-9;
DE   AltName: CD_antigen=CD329;
DE   Flags: Precursor;
GN   Name=SIGLEC9; ORFNames=UNQ668/PRO1302;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; NAS:UniProtKB.
//
ID   SIK1_HUMAN              Reviewed;         783 AA.
AC   P57059; A6NC84; Q5R2V5; Q6ZNL8; Q86YJ2;
DE   RecName: Full=Serine/threonine-protein kinase SIK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Salt-inducible kinase 1;
DE            Short=SIK-1;
DE   AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 1;
DE            Short=Serine/threonine-protein kinase SNF1LK;
GN   Name=SIK1; Synonyms=SIK, SNF1LK;
DR   GuidetoPHARMACOLOGY; 2197; -.
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0008140; F:cAMP response element binding protein binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043276; P:anoikis; IEA:Ensembl.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0032792; P:negative regulation of CREB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:UniProtKB.
DR   GO; GO:2000210; P:positive regulation of anoikis; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045595; P:regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; ISS:UniProtKB.
DR   GO; GO:0010830; P:regulation of myotube differentiation; ISS:UniProtKB.
DR   GO; GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
//
ID   SIK3_HUMAN              Reviewed;        1263 AA.
AC   Q9Y2K2; A1A5A8; Q59FY2; Q5M9N1; Q6P3R6; Q8IYM8; Q9HA50;
DE   RecName: Full=Serine/threonine-protein kinase SIK3;
DE            EC=2.7.11.1;
DE   AltName: Full=Salt-inducible kinase 3;
DE            Short=SIK-3;
DE   AltName: Full=Serine/threonine-protein kinase QSK;
GN   Name=SIK3; Synonyms=KIAA0999, QSK; ORFNames=L19;
DR   GuidetoPHARMACOLOGY; 2199; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
//
ID   SIK2_HUMAN              Reviewed;         926 AA.
AC   Q9H0K1; A8K5B8; B0YJ94; O94878; Q17RV0; Q6AZE2; Q76N03; Q8NCV7;
AC   Q96CZ8;
DE   RecName: Full=Serine/threonine-protein kinase SIK2;
DE            EC=2.7.11.1;
DE   AltName: Full=Qin-induced kinase;
DE   AltName: Full=Salt-inducible kinase 2;
DE            Short=SIK-2;
DE   AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 2;
GN   Name=SIK2; Synonyms=KIAA0781, QIK, SNF1LK2;
DR   GuidetoPHARMACOLOGY; 2198; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
//
ID   SIKE1_HUMAN             Reviewed;         207 AA.
AC   Q9BRV8; Q5TEZ7; Q5TEZ9; Q68DZ4; Q9H778;
DE   RecName: Full=Suppressor of IKBKE 1;
DE   AltName: Full=Suppressor of IKK-epsilon;
GN   Name=SIKE1; Synonyms=SIKE;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   SIL1_HUMAN              Reviewed;         461 AA.
AC   Q9H173; D3DQC2; Q8N2L3;
DE   RecName: Full=Nucleotide exchange factor SIL1;
DE   AltName: Full=BiP-associated protein;
DE            Short=BAP;
DE   Flags: Precursor;
GN   Name=SIL1; ORFNames=UNQ545/PRO836;
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   SIM10_HUMAN             Reviewed;          83 AA.
AC   Q96HG1;
DE   RecName: Full=Small integral membrane protein 10;
GN   Name=SMIM10; Synonyms=CXorf69;
//
ID   SIM11_HUMAN             Reviewed;          58 AA.
AC   P58511;
DE   RecName: Full=Small integral membrane protein 11;
GN   Name=SMIM11; Synonyms=C21orf51, FAM165B;
//
ID   SIM13_HUMAN             Reviewed;          91 AA.
AC   P0DJ93; G3V581;
DE   RecName: Full=Small integral membrane protein 13;
GN   Name=SMIM13; Synonyms=C6orf228;
//
ID   SIM12_HUMAN             Reviewed;          92 AA.
AC   Q96EX1; D3DPR5; Q49AP7; Q52LP9; Q8NCB4;
DE   RecName: Full=Small integral membrane protein 12;
GN   Name=SMIM12; Synonyms=C1orf212;
//
ID   SIM14_HUMAN             Reviewed;          99 AA.
AC   Q96QK8;
DE   RecName: Full=Small integral membrane protein 14;
GN   Name=SMIM14; Synonyms=C4orf34;
//
ID   SIM15_HUMAN             Reviewed;          74 AA.
AC   Q7Z3B0; B9EJC4;
DE   RecName: Full=Small integral membrane protein 15;
GN   Name=SMIM15; Synonyms=C5orf43;
//
ID   SIM1_HUMAN              Reviewed;         766 AA.
AC   P81133; Q5TDP7;
DE   RecName: Full=Single-minded homolog 1;
DE   AltName: Full=Class E basic helix-loop-helix protein 14;
DE            Short=bHLHe14;
GN   Name=SIM1; Synonyms=BHLHE14;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   SIM16_HUMAN             Reviewed;          91 AA.
AC   A6NCI5;
DE   RecName: Full=Putative transmembrane protein encoded by LINC00862;
DE   AltName: Full=Small integral membrane protein 16;
GN   Name=LINC00862; Synonyms=C1orf98, SMIM16;
//
ID   SIM18_HUMAN             Reviewed;          95 AA.
AC   P0DKX4;
DE   RecName: Full=Small integral membrane protein 18;
GN   Name=SMIM18;
//
ID   SIM22_HUMAN             Reviewed;         135 AA.
AC   K7EJ46; K7EIG5; K7EIH2;
DE   RecName: Full=Small integral membrane protein 22;
GN   Name=SMIM22;
//
ID   SIM17_HUMAN             Reviewed;         118 AA.
AC   P0DL12;
DE   RecName: Full=Small integral membrane protein 17;
GN   Name=SMIM17;
//
ID   SIM23_HUMAN             Reviewed;         156 AA.
AC   A6NLE4;
DE   RecName: Full=Small integral membrane protein 23;
GN   Name=SMIM23; Synonyms=C5orf50;
//
ID   SIM24_HUMAN             Reviewed;         130 AA.
AC   O75264; B9EJF4; Q9P059;
DE   RecName: Full=Small integral membrane protein 24;
DE   Flags: Precursor;
GN   Name=SMIM24; Synonyms=C19orf77; ORFNames=HSPC323;
//
ID   SIM2_HUMAN              Reviewed;         667 AA.
AC   Q14190; O60766; Q15470; Q15471; Q15472; Q15473; Q16532; Q2TBD8;
DE   RecName: Full=Single-minded homolog 2;
DE   AltName: Full=Class E basic helix-loop-helix protein 15;
DE            Short=bHLHe15;
GN   Name=SIM2; Synonyms=BHLHE15;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SIMC1_HUMAN             Reviewed;         872 AA.
AC   Q8NDZ2; J3KQQ8; Q6NXN8; Q6ZTU4; Q8IZ15;
DE   RecName: Full=SUMO-interacting motif-containing protein 1;
GN   Name=SIMC1; Synonyms=C5orf25;
DR   GO; GO:0032184; F:SUMO polymer binding; IDA:UniProtKB.
//
ID   SIN1_HUMAN              Reviewed;         522 AA.
AC   Q9BPZ7; A8K1Z5; B1AMA4; B7Z309; Q00426; Q5JSV5; Q5JSV6; Q5JSV9;
AC   Q658R0; Q699U1; Q699U2; Q699U3; Q699U4; Q6GVJ0; Q6GVJ1; Q6GVJ2;
DE   RecName: Full=Target of rapamycin complex 2 subunit MAPKAP1;
DE            Short=TORC2 subunit MAPKAP1;
DE   AltName: Full=Mitogen-activated protein kinase 2-associated protein 1;
DE   AltName: Full=Stress-activated map kinase-interacting protein 1;
DE            Short=SAPK-interacting protein 1;
DE            Short=mSIN1;
GN   Name=MAPKAP1; Synonyms=MIP1, SIN1;
DR   GO; GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017016; F:Ras GTPase binding; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   SIN3A_HUMAN             Reviewed;        1273 AA.
AC   Q96ST3; B2RNS5; Q8N8N4; Q8NC83; Q8WV18; Q96L98; Q9UFQ1;
DE   RecName: Full=Paired amphipathic helix protein Sin3a;
DE   AltName: Full=Histone deacetylase complex subunit Sin3a;
DE   AltName: Full=Transcriptional corepressor Sin3a;
GN   Name=SIN3A;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IMP:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0002218; P:activation of innate immune response; IMP:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:1901675; P:negative regulation of histone H3-K27 acetylation; IMP:BHF-UCL.
DR   GO; GO:1900181; P:negative regulation of protein localization to nucleus; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0031937; P:positive regulation of chromatin silencing; IMP:BHF-UCL.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:BHF-UCL.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006476; P:protein deacetylation; IMP:BHF-UCL.
DR   GO; GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0051595; P:response to methylglyoxal; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SIN3B_HUMAN             Reviewed;        1162 AA.
AC   O75182; Q2NL91; Q68GC2; Q6P4B8; Q8TB34; Q9BSC8;
DE   RecName: Full=Paired amphipathic helix protein Sin3b;
DE   AltName: Full=Histone deacetylase complex subunit Sin3b;
DE   AltName: Full=Transcriptional corepressor Sin3b;
GN   Name=SIN3B; Synonyms=KIAA0700;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SIPA1_HUMAN             Reviewed;        1042 AA.
AC   Q96FS4; O14518; O60484; O60618; Q2YD83;
DE   RecName: Full=Signal-induced proliferation-associated protein 1;
DE            Short=Sipa-1;
DE   AltName: Full=GTPase-activating protein Spa-1;
DE   AltName: Full=p130 SPA-1;
GN   Name=SIPA1; Synonyms=SPA1;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046582; F:Rap GTPase activator activity; NAS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0042631; P:cellular response to water deprivation; IEA:Ensembl.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; NAS:UniProtKB.
DR   GO; GO:0045786; P:negative regulation of cell cycle; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0032854; P:positive regulation of Rap GTPase activity; NAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SIR1_HUMAN              Reviewed;         747 AA.
AC   Q96EB6; Q2XNF6; Q5JVQ0; Q9GZR9; Q9Y6F0;
DE   RecName: Full=NAD-dependent protein deacetylase sirtuin-1;
DE            Short=hSIRT1;
DE            EC=3.5.1.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 1;
DE   AltName: Full=SIR2-like protein 1;
DE            Short=hSIR2;
DE   Contains:
DE     RecName: Full=SirtT1 75 kDa fragment;
DE              Short=75SirT1;
GN   Name=SIRT1; Synonyms=SIR2L1;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0019213; F:deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IPI:BHF-UCL.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0043398; F:HLH domain binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0017136; F:NAD-dependent histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); ISS:UniProtKB.
DR   GO; GO:0034979; F:NAD-dependent protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0007569; P:cell aging; TAS:BHF-UCL.
DR   GO; GO:0001678; P:cellular glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:BHF-UCL.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; ISS:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0035356; P:cellular triglyceride homeostasis; ISS:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; ISS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; IMP:UniProt.
DR   GO; GO:0006342; P:chromatin silencing; TAS:ProtInc.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:BHF-UCL.
DR   GO; GO:0006260; P:DNA replication; TAS:BHF-UCL.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; ISS:UniProtKB.
DR   GO; GO:0006343; P:establishment of chromatin silencing; IDA:BHF-UCL.
DR   GO; GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; IDA:UniProtKB.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:BHF-UCL.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0006344; P:maintenance of chromatin silencing; IMP:BHF-UCL.
DR   GO; GO:0006346; P:methylation-dependent chromatin silencing; TAS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000480; P:negative regulation of cAMP-dependent protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:2000655; P:negative regulation of cellular response to testosterone stimulus; IMP:BHF-UCL.
DR   GO; GO:2000773; P:negative regulation of cellular senescence; IDA:UniProtKB.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0051097; P:negative regulation of helicase activity; IDA:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; ISS:BHF-UCL.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:2000757; P:negative regulation of peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IMP:UniProtKB.
DR   GO; GO:0031393; P:negative regulation of prostaglandin biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0001542; P:ovulation from ovarian follicle; IEA:Ensembl.
DR   GO; GO:0018394; P:peptidyl-lysine acetylation; IMP:UniProtKB.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; IDA:BHF-UCL.
DR   GO; GO:0002821; P:positive regulation of adaptive immune response; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2000481; P:positive regulation of cAMP-dependent protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:2000774; P:positive regulation of cellular senescence; IDA:UniProtKB.
DR   GO; GO:0010875; P:positive regulation of cholesterol efflux; ISS:UniProtKB.
DR   GO; GO:0031937; P:positive regulation of chromatin silencing; IMP:BHF-UCL.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0051574; P:positive regulation of histone H3-K9 methylation; IMP:UniProt.
DR   GO; GO:0046628; P:positive regulation of insulin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IDA:UniProtKB.
DR   GO; GO:2000111; P:positive regulation of macrophage apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000720; P:pyrimidine dimer repair by nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0070857; P:regulation of bile acid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0032071; P:regulation of endodeoxyribonuclease activity; IMP:UniProtKB.
DR   GO; GO:0010906; P:regulation of glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0035358; P:regulation of peroxisome proliferator activated receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0033158; P:regulation of protein import into nucleus, translocation; IMP:UniProtKB.
DR   GO; GO:0034391; P:regulation of smooth muscle cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; ISS:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0000012; P:single strand break repair; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006642; P:triglyceride mobilization; ISS:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
DR   GO; GO:0050872; P:white fat cell differentiation; ISS:BHF-UCL.
//
ID   SIR2_HUMAN              Reviewed;         389 AA.
AC   Q8IXJ6; A8K3V1; B2RB45; O95889; Q924Y7; Q9P0G8; Q9UNT0; Q9Y6E9;
DE   RecName: Full=NAD-dependent protein deacetylase sirtuin-2;
DE            EC=3.5.1.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 2;
DE   AltName: Full=SIR2-like protein 2;
GN   Name=SIRT2; Synonyms=SIR2L, SIR2L2;
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0004407; F:histone deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0070403; F:NAD+ binding; IDA:UniProtKB.
DR   GO; GO:0017136; F:NAD-dependent histone deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0046970; F:NAD-dependent histone deacetylase activity (H4-K16 specific); IDA:UniProtKB.
DR   GO; GO:0034979; F:NAD-dependent protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033558; F:protein deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0042903; F:tubulin deacetylase activity; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006342; P:chromatin silencing; NAS:UniProtKB.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; NAS:UniProtKB.
DR   GO; GO:0006348; P:chromatin silencing at telomere; NAS:UniProtKB.
DR   GO; GO:0016458; P:gene silencing; NAS:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; TAS:UniProtKB.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0070446; P:negative regulation of oligodendrocyte progenitor proliferation; ISS:UniProtKB.
DR   GO; GO:0045843; P:negative regulation of striated muscle tissue development; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; NAS:UniProtKB.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0007096; P:regulation of exit from mitosis; NAS:UniProtKB.
DR   GO; GO:0042325; P:regulation of phosphorylation; NAS:UniProtKB.
DR   GO; GO:0051775; P:response to redox state; NAS:UniProtKB.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0090042; P:tubulin deacetylation; IDA:UniProtKB.
//
ID   SIR3_HUMAN              Reviewed;         399 AA.
AC   Q9NTG7; B7Z5U6; Q9Y6E8;
DE   RecName: Full=NAD-dependent protein deacetylase sirtuin-3, mitochondrial;
DE            Short=hSIRT3;
DE            EC=3.5.1.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 3;
DE   AltName: Full=SIR2-like protein 3;
DE   Flags: Precursor;
GN   Name=SIRT3; Synonyms=SIR2L3;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0032041; F:NAD-dependent histone deacetylase activity (H3-K14 specific); IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009060; P:aerobic respiration; IMP:UniProtKB.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; IMP:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
//
ID   SIR4_HUMAN              Reviewed;         314 AA.
AC   Q9Y6E7; O43346; Q32M33;
DE   RecName: Full=NAD-dependent protein deacetylase sirtuin-4;
DE            EC=3.5.1.-;
DE   AltName: Full=NAD-dependent ADP-ribosyltransferase sirtuin-4;
DE            EC=2.4.2.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 4;
DE   AltName: Full=SIR2-like protein 4;
DE   Flags: Precursor;
GN   Name=SIRT4; Synonyms=SIR2L4;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0070403; F:NAD+ binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:UniProtKB.
DR   GO; GO:0006342; P:chromatin silencing; TAS:ProtInc.
DR   GO; GO:0006541; P:glutamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0046322; P:negative regulation of fatty acid oxidation; ISS:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IMP:UniProtKB.
DR   GO; GO:0034983; P:peptidyl-lysine deacetylation; ISS:UniProtKB.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; ISS:UniProtKB.
DR   GO; GO:0072350; P:tricarboxylic acid metabolic process; ISS:UniProtKB.
//
ID   SIR5_HUMAN              Reviewed;         310 AA.
AC   Q9NXA8; B4DFM4; B4DYJ5; F5H5Z9; Q5T294; Q5T295; Q9Y6E6;
DE   RecName: Full=NAD-dependent protein deacylase sirtuin-5, mitochondrial;
DE            EC=3.5.1.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 5;
DE   AltName: Full=SIR2-like protein 5;
DE   Flags: Precursor;
GN   Name=SIRT5; Synonyms=SIR2L5;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0070403; F:NAD+ binding; IDA:UniProtKB.
DR   GO; GO:0036054; F:protein-malonyllysine demalonylase activity; IDA:UniProtKB.
DR   GO; GO:0036055; F:protein-succinyllysine desuccinylase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006342; P:chromatin silencing; TAS:ProtInc.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0036047; P:peptidyl-lysine demalonylation; IDA:UniProtKB.
DR   GO; GO:0036049; P:peptidyl-lysine desuccinylation; IDA:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc.
DR   GO; GO:0006476; P:protein deacetylation; IDA:UniProtKB.
DR   GO; GO:0036048; P:protein desuccinylation; IDA:UniProtKB.
//
ID   SIR6_HUMAN              Reviewed;         355 AA.
AC   Q8N6T7; B2RCD0; O75291; Q6IAF5; Q6PK99; Q8NCD2; Q9BSI5; Q9BWP3;
AC   Q9NRC7; Q9UQD1;
DE   RecName: Full=NAD-dependent protein deacetylase sirtuin-6;
DE            EC=3.5.1.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 6;
DE   AltName: Full=SIR2-like protein 6;
GN   Name=SIRT6; Synonyms=SIR2L6;
DR   GO; GO:0003956; F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; TAS:BHF-UCL.
DR   GO; GO:0070403; F:NAD+ binding; ISS:UniProtKB.
DR   GO; GO:0017136; F:NAD-dependent histone deacetylase activity; ISS:UniProtKB.
DR   GO; GO:0046969; F:NAD-dependent histone deacetylase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0016575; P:histone deacetylation; ISS:GOC.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:GOC.
DR   GO; GO:0006471; P:protein ADP-ribosylation; ISS:UniProtKB.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.
//
ID   SIR7_HUMAN              Reviewed;         400 AA.
AC   Q9NRC8; A8K2K0; B3KSU8; Q3MIK4; Q9NSZ6; Q9NUS6;
DE   RecName: Full=NAD-dependent protein deacetylase sirtuin-7;
DE            EC=3.5.1.-;
DE   AltName: Full=Regulatory protein SIR2 homolog 7;
DE   AltName: Full=SIR2-like protein 7;
GN   Name=SIRT7; Synonyms=SIR2L7;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0097372; F:NAD-dependent histone deacetylase activity (H3-K18 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070932; P:histone H3 deacetylation; IDA:UniProtKB.
DR   GO; GO:0070933; P:histone H4 deacetylation; IDA:GOC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007072; P:positive regulation of transcription on exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0009303; P:rRNA transcription; IMP:UniProtKB.
//
ID   SIRB1_HUMAN             Reviewed;         398 AA.
AC   O00241; A6NLM2; B2R8V0; Q5TFQ9; Q5TFR0; Q8TB12; Q9H1U5; Q9Y4V0;
DE   RecName: Full=Signal-regulatory protein beta-1;
DE            Short=SIRP-beta-1;
DE   AltName: Full=CD172 antigen-like family member B;
DE   AltName: CD_antigen=CD172b;
DE   Flags: Precursor;
GN   Name=SIRPB1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SIRBL_HUMAN             Reviewed;         398 AA.
AC   Q5TFQ8; Q7Z3B9;
DE   RecName: Full=Signal-regulatory protein beta-1 isoform 3;
DE            Short=SIRP-beta-1 isoform 3;
DE   Flags: Precursor;
GN   Name=SIRPB1;
//
ID   SIRB2_HUMAN             Reviewed;         342 AA.
AC   Q5JXA9; B4DLM9; E9PCW6; Q6TCH9;
DE   RecName: Full=Signal-regulatory protein beta-2;
DE            Short=SIRP-beta-2;
DE   AltName: Full=Protein tyrosine phosphatase non-receptor type substrate 1-like 3;
DE   AltName: Full=Protein tyrosine phosphatase non-receptor type substrate protein;
DE   Flags: Precursor;
GN   Name=SIRPB2; Synonyms=PTPN1L, PTPNS1L3;
//
ID   SIRPD_HUMAN             Reviewed;         197 AA.
AC   Q9H106; B3KS88; Q5TFQ6;
DE   RecName: Full=Signal-regulatory protein delta;
DE            Short=SIRP-delta;
DE   AltName: Full=Protein tyrosine phosphatase non-receptor type substrate 1-like 2;
DE   Flags: Precursor;
GN   Name=SIRPD; Synonyms=PTPNS1L2;
//
ID   SIRPG_HUMAN             Reviewed;         387 AA.
AC   Q9P1W8; B1AKP6; Q5D051; Q5JV25; Q5MKL4; Q8WWA5; Q9NQK8;
DE   RecName: Full=Signal-regulatory protein gamma;
DE            Short=SIRP-gamma;
DE   AltName: Full=CD172 antigen-like family member B;
DE   AltName: Full=Signal-regulatory protein beta-2;
DE            Short=SIRP-b2;
DE            Short=SIRP-beta-2;
DE   AltName: CD_antigen=CD172g;
DE   Flags: Precursor;
GN   Name=SIRPG; Synonyms=SIRPB2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IDA:UniProtKB.
//
ID   SIT1_HUMAN              Reviewed;         196 AA.
AC   Q9Y3P8; B2RBP9;
DE   RecName: Full=Signaling threshold-regulating transmembrane adapter 1;
DE   AltName: Full=SHP2-interacting transmembrane adapter protein;
DE   AltName: Full=Suppression-inducing transmembrane adapter 1;
DE   AltName: Full=gp30/40;
DE   Flags: Precursor;
GN   Name=SIT1; Synonyms=SIT;
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; TAS:HGNC.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0050863; P:regulation of T cell activation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SIVA_HUMAN              Reviewed;         175 AA.
AC   O15304; Q96P98; Q9UPD6;
DE   RecName: Full=Apoptosis regulatory protein Siva;
DE   AltName: Full=CD27-binding protein;
DE            Short=CD27BP;
GN   Name=SIVA1; Synonyms=SIVA;
DR   GO; GO:0005175; F:CD27 receptor binding; IPI:HGNC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0001618; F:virus receptor activity; ISS:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IDA:HGNC.
DR   GO; GO:0006924; P:activation-induced cell death of T cells; IDA:HGNC.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:HGNC.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; ISS:GOC.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SIX1_HUMAN              Reviewed;         284 AA.
AC   Q15475; Q53Y16; Q96H64;
DE   RecName: Full=Homeobox protein SIX1;
DE   AltName: Full=Sine oculis homeobox homolog 1;
GN   Name=SIX1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0035909; P:aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0021610; P:facial nerve morphogenesis; IEA:Ensembl.
DR   GO; GO:0048699; P:generation of neurons; ISS:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; ISS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:UniProtKB.
DR   GO; GO:0072172; P:mesonephric tubule formation; ISS:UniProtKB.
DR   GO; GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0051451; P:myoblast migration; ISS:UniProtKB.
DR   GO; GO:0090191; P:negative regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0001759; P:organ induction; ISS:UniProtKB.
DR   GO; GO:0071599; P:otic vesicle development; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; ISS:UniProtKB.
DR   GO; GO:0060037; P:pharyngeal system development; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:2000729; P:positive regulation of mesenchymal cell proliferation involved in ureter development; IEA:Ensembl.
DR   GO; GO:0072513; P:positive regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0072107; P:positive regulation of ureteric bud formation; ISS:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
DR   GO; GO:0072095; P:regulation of branch elongation involved in ureteric bud branching; ISS:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0048538; P:thymus development; ISS:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0072193; P:ureter smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
//
ID   SIX2_HUMAN              Reviewed;         291 AA.
AC   Q9NPC8; Q9BXH7;
DE   RecName: Full=Homeobox protein SIX2;
DE   AltName: Full=Sine oculis homeobox homolog 2;
GN   Name=SIX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IMP:UniProtKB.
DR   GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0007501; P:mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
//
ID   SIX3_HUMAN              Reviewed;         332 AA.
AC   O95343; D6W5A5; Q53T42;
DE   RecName: Full=Homeobox protein SIX3;
DE   AltName: Full=Sine oculis homeobox homolog 3;
GN   Name=SIX3;
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0048512; P:circadian behavior; IEA:Ensembl.
DR   GO; GO:0021536; P:diencephalon development; IEA:Ensembl.
DR   GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   SIX4_HUMAN              Reviewed;         781 AA.
AC   Q9UIU6; Q4QQH5; Q4V764;
DE   RecName: Full=Homeobox protein SIX4;
DE   AltName: Full=Sine oculis homeobox homolog 4;
GN   Name=SIX4;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0048699; P:generation of neurons; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0072075; P:metanephric mesenchyme development; IEA:Ensembl.
DR   GO; GO:0051451; P:myoblast migration; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0072107; P:positive regulation of ureteric bud formation; IEA:Ensembl.
DR   GO; GO:0072095; P:regulation of branch elongation involved in ureteric bud branching; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0008582; P:regulation of synaptic growth at neuromuscular junction; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   SIX5_HUMAN              Reviewed;         739 AA.
AC   Q8N196;
DE   RecName: Full=Homeobox protein SIX5;
DE   AltName: Full=DM locus-associated homeodomain protein;
DE   AltName: Full=Sine oculis homeobox homolog 5;
GN   Name=SIX5; Synonyms=DMAHP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SIX6_HUMAN              Reviewed;         246 AA.
AC   O95475; Q6NT42; Q9P1X8;
DE   RecName: Full=Homeobox protein SIX6;
DE   AltName: Full=Homeodomain protein OPTX2;
DE   AltName: Full=Optic homeobox 2;
DE   AltName: Full=Sine oculis homeobox homolog 6;
GN   Name=SIX6; Synonyms=OPTX2, SIX9;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   SK2L2_HUMAN             Reviewed;        1042 AA.
AC   P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2;
DE   RecName: Full=Superkiller viralicidic activity 2-like 2;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent RNA helicase SKIV2L2;
DE   AltName: Full=TRAMP-like complex helicase;
GN   Name=SKIV2L2; Synonyms=KIAA0052, Mtr4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   SKA1_HUMAN              Reviewed;         255 AA.
AC   Q96BD8; B2R9Y6; B4E0P4;
DE   RecName: Full=Spindle and kinetochore-associated protein 1;
GN   Name=SKA1; Synonyms=C18orf24;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IDA:UniProtKB.
//
ID   SKA2_HUMAN              Reviewed;         121 AA.
AC   Q8WVK7; A6NIL3; B3KPL3; E9PCB8;
DE   RecName: Full=Spindle and kinetochore-associated protein 2;
DE   AltName: Full=Protein FAM33A;
GN   Name=SKA2; Synonyms=FAM33A;
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IDA:UniProtKB.
//
ID   SKA3_HUMAN              Reviewed;         412 AA.
AC   Q8IX90; A2A330; A2A331; B2RBY2; Q5VZV5; Q86WR2; Q8NBG1; Q96D22;
DE   RecName: Full=Spindle and kinetochore-associated protein 3;
GN   Name=SKA3; Synonyms=C13orf3, RAMA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IMP:UniProtKB.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IDA:UniProtKB.
//
ID   SKAP1_HUMAN             Reviewed;         359 AA.
AC   Q86WV1; D3DTV1; O15268;
DE   RecName: Full=Src kinase-associated phosphoprotein 1;
DE   AltName: Full=Src family-associated phosphoprotein 1;
DE   AltName: Full=Src kinase-associated phosphoprotein of 55 kDa;
DE            Short=SKAP-55;
DE            Short=pp55;
GN   Name=SKAP1; Synonyms=SCAP1, SKAP55;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0017124; F:SH3 domain binding; TAS:BHF-UCL.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IC:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IC:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.
//
ID   SKAP2_HUMAN             Reviewed;         359 AA.
AC   O75563; A4D173; Q53GP6; Q75MK6; Q75MZ4; Q9UBZ3; Q9UED8;
DE   RecName: Full=Src kinase-associated phosphoprotein 2;
DE   AltName: Full=Pyk2/RAFTK-associated protein;
DE   AltName: Full=Retinoic acid-induced protein 70;
DE   AltName: Full=SKAP55 homolog;
DE            Short=SKAP-55HOM;
DE            Short=SKAP-HOM;
DE   AltName: Full=Src family-associated phosphoprotein 2;
DE   AltName: Full=Src kinase-associated phosphoprotein 55-related protein;
DE   AltName: Full=Src-associated adapter protein with PH and SH3 domains;
GN   Name=SKAP2; Synonyms=PRAP, RA70, SAPS, SCAP2, SKAP55R;
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0042113; P:B cell activation; IEA:UniProtKB-KW.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SKAP_HUMAN              Reviewed;         316 AA.
AC   Q9Y448; B4DXA7; Q147U5; Q32Q57; Q5ISJ0; Q6P2S5; Q6PJM0; Q86XB4;
DE   RecName: Full=Small kinetochore-associated protein;
DE            Short=SKAP;
DE   AltName: Full=Kinetochore-localized astrin-binding protein;
DE            Short=Kinastrin;
DE   AltName: Full=Kinetochore-localized astrin/SPAG5-binding protein;
DE   AltName: Full=TRAF4-associated factor 1;
GN   Name=KNSTRN; Synonyms=C15orf23, SKAP, TRAF4AF1; ORFNames=HSD11;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   SKDA1_HUMAN             Reviewed;         827 AA.
AC   Q1XH10; B1ANA5; Q6ZMX4; Q8N3C3;
DE   RecName: Full=SKI/DACH domain-containing protein 1;
DE   AltName: Full=Protein DLN-1;
GN   Name=SKIDA1; Synonyms=C10orf140, DLN1;
//
ID   SKIT1_HUMAN             Reviewed;         218 AA.
AC   A8MVG2;
DE   RecName: Full=Putative selection and upkeep of intraepithelial T-cells protein 1 homolog;
DE            Short=Skint-1;
DE   AltName: Full=Skint-like pseudogene;
GN   Name=SKINTL; Synonyms=SKINT1;
//
ID   SKIL_HUMAN              Reviewed;         684 AA.
AC   P12757; A6NGT1; B4DT50; O00464; P12756; Q07501;
DE   RecName: Full=Ski-like protein;
DE   AltName: Full=Ski-related oncogene;
DE   AltName: Full=Ski-related protein;
GN   Name=SKIL; Synonyms=SNO;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0001825; P:blastocyst formation; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0002260; P:lymphocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:1902231; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0070208; P:protein heterotrimerization; IDA:UniProtKB.
DR   GO; GO:0070207; P:protein homotrimerization; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0046677; P:response to antibiotic; IEP:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0070848; P:response to growth factor; IDA:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   SKIV2_HUMAN             Reviewed;        1246 AA.
AC   Q15477; O15005; Q12902; Q15476; Q5ST66;
DE   RecName: Full=Helicase SKI2W;
DE            Short=Ski2;
DE            EC=3.6.4.-;
DE   AltName: Full=Helicase-like protein;
DE            Short=HLP;
GN   Name=SKIV2L; Synonyms=DDX13, SKI2W, SKIV2, W;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
//
ID   SKI_HUMAN               Reviewed;         728 AA.
AC   P12755; Q5SYT7;
DE   RecName: Full=Ski oncogene;
DE   AltName: Full=Proto-oncogene c-Ski;
GN   Name=SKI;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046811; F:histone deacetylase inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0060349; P:bone morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0043010; P:camera-type eye development; ISS:BHF-UCL.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0048870; P:cell motility; NAS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; NAS:BHF-UCL.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060325; P:face morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0022011; P:myelination in peripheral nervous system; ISS:BHF-UCL.
DR   GO; GO:0014902; P:myotube differentiation; IDA:UniProtKB.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0010626; P:negative regulation of Schwann cell proliferation; IGI:MGI.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; ISS:BHF-UCL.
DR   GO; GO:0043585; P:nose morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0021772; P:olfactory bulb development; ISS:BHF-UCL.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0070207; P:protein homotrimerization; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0060041; P:retina development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0048741; P:skeletal muscle fiber development; ISS:BHF-UCL.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; ISS:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; NAS:BHF-UCL.
//
ID   SKOR1_HUMAN             Reviewed;         965 AA.
AC   P84550; A6NIP4; A6NJY0; Q2VWA5;
DE   RecName: Full=SKI family transcriptional corepressor 1;
DE   AltName: Full=Functional Smad-suppressing element on chromosome 15;
DE            Short=Fussel-15;
DE   AltName: Full=LBX1 corepressor 1;
DE   AltName: Full=Ladybird homeobox corepressor 1;
GN   Name=SKOR1; Synonyms=CORL1, FUSSEL15, LBXCOR1;
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SKOR2_HUMAN             Reviewed;        1001 AA.
AC   Q2VWA4;
DE   RecName: Full=SKI family transcriptional corepressor 2;
DE   AltName: Full=Functional Smad-suppressing element on chromosome 18;
DE            Short=Fussel-18;
DE   AltName: Full=LBX1 corepressor 1-like protein;
DE   AltName: Full=Ladybird homeobox corepressor 1-like protein;
GN   Name=SKOR2; Synonyms=CORL2, FUSSEL18;
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0021936; P:regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SKP1_HUMAN              Reviewed;         163 AA.
AC   P63208; D3DQ97; D3DQ98; P34991; Q8TAY2;
DE   RecName: Full=S-phase kinase-associated protein 1;
DE   AltName: Full=Cyclin-A/CDK2-associated protein p19;
DE            Short=p19A;
DE   AltName: Full=Organ of Corti protein 2;
DE            Short=OCP-2;
DE   AltName: Full=Organ of Corti protein II;
DE            Short=OCP-II;
DE   AltName: Full=RNA polymerase II elongation factor-like protein;
DE   AltName: Full=SIII;
DE   AltName: Full=Transcription elongation factor B polypeptide 1-like;
DE   AltName: Full=p19skp1;
GN   Name=SKP1; Synonyms=EMC19, OCP2, SKP1A, TCEB1L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   SKP2_HUMAN              Reviewed;         424 AA.
AC   Q13309; A8K5E0; B4DJT4; Q8TDZ0; Q8TDZ1; Q9BV69;
DE   RecName: Full=S-phase kinase-associated protein 2;
DE   AltName: Full=Cyclin-A/CDK2-associated protein p45;
DE   AltName: Full=F-box protein Skp2;
DE   AltName: Full=F-box/LRR-repeat protein 1;
DE   AltName: Full=p45skp2;
GN   Name=SKP2; Synonyms=FBXL1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071460; P:cellular response to cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
//
ID   SKT_HUMAN               Reviewed;        1943 AA.
AC   Q5T5P2; A5LHW9; A6NLF3; A6PVQ5; A6PVQ6; A6PVQ7; B9EGK4; Q4KMG4;
AC   Q5T5P3; Q5T7H3; Q6MZZ6; Q6ZUI4; Q8WV45; Q9NSR2; Q9ULK3;
DE   RecName: Full=Sickle tail protein homolog;
GN   Name=KIAA1217; Synonyms=SKT;
DR   GO; GO:0048706; P:embryonic skeletal system development; ISS:UniProtKB.
//
ID   SL9A1_HUMAN             Reviewed;         815 AA.
AC   P19634; B1ALD6; D3DPL4; Q96EM2;
DE   RecName: Full=Sodium/hydrogen exchanger 1;
DE   AltName: Full=APNH;
DE   AltName: Full=Na(+)/H(+) antiporter, amiloride-sensitive;
DE   AltName: Full=Na(+)/H(+) exchanger 1;
DE            Short=NHE-1;
DE   AltName: Full=Solute carrier family 9 member 1;
GN   Name=SLC9A1; Synonyms=APNH1, NHE1;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IDA:UniProtKB.
DR   GO; GO:0015299; F:solute:proton antiporter activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; IEA:Ensembl.
DR   GO; GO:0071468; P:cellular response to acidity; ISS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0070997; P:neuron death; IEA:Ensembl.
DR   GO; GO:0045760; P:positive regulation of action potential; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0035794; P:positive regulation of mitochondrial membrane permeability; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; ISS:UniProtKB.
DR   GO; GO:0051453; P:regulation of intracellular pH; IDA:UniProtKB.
DR   GO; GO:0006885; P:regulation of pH; IDA:UniProtKB.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0002026; P:regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0001101; P:response to acid; IDA:UniProtKB.
DR   GO; GO:0010447; P:response to acidity; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0071436; P:sodium ion export; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9A2_HUMAN             Reviewed;         812 AA.
AC   Q9UBY0; B2RMS2;
DE   RecName: Full=Sodium/hydrogen exchanger 2;
DE   AltName: Full=Na(+)/H(+) exchanger 2;
DE            Short=NHE-2;
DE   AltName: Full=Solute carrier family 9 member 2;
GN   Name=SLC9A2; Synonyms=NHE2;
DR   GO; GO:0015385; F:sodium:proton antiporter activity; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9A3_HUMAN             Reviewed;         834 AA.
AC   P48764; B7ZKR2; E9PF67; Q3MIW3;
DE   RecName: Full=Sodium/hydrogen exchanger 3;
DE   AltName: Full=Na(+)/H(+) exchanger 3;
DE            Short=NHE-3;
DE   AltName: Full=Solute carrier family 9 member 3;
GN   Name=SLC9A3; Synonyms=NHE3;
DR   GO; GO:0030165; F:PDZ domain binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006885; P:regulation of pH; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; ISS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9A4_HUMAN             Reviewed;         798 AA.
AC   Q6AI14; Q69YK0;
DE   RecName: Full=Sodium/hydrogen exchanger 4;
DE   AltName: Full=Na(+)/H(+) exchanger 4;
DE            Short=NHE-4;
DE   AltName: Full=Solute carrier family 9 member 4;
GN   Name=SLC9A4; Synonyms=NHE4;
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9A5_HUMAN             Reviewed;         896 AA.
AC   Q14940; A5PKY7; Q9Y626;
DE   RecName: Full=Sodium/hydrogen exchanger 5;
DE   AltName: Full=Na(+)/H(+) exchanger 5;
DE            Short=NHE-5;
DE   AltName: Full=Solute carrier family 9 member 5;
GN   Name=SLC9A5; Synonyms=NHE5;
DR   GO; GO:0015385; F:sodium:proton antiporter activity; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SL9A6_HUMAN             Reviewed;         669 AA.
AC   Q92581; A6NIQ9; A8K160; B4DU30; B7ZAE0; Q3ZCW7; Q5JPP8; Q5JPP9;
AC   Q86VS0;
DE   RecName: Full=Sodium/hydrogen exchanger 6;
DE   AltName: Full=Na(+)/H(+) exchanger 6;
DE            Short=NHE-6;
DE   AltName: Full=Solute carrier family 9 member 6;
GN   Name=SLC9A6; Synonyms=KIAA0267, NHE6;
DR   GO; GO:0015385; F:sodium:proton antiporter activity; TAS:ProtInc.
DR   GO; GO:0048675; P:axon extension; IDA:MGI.
DR   GO; GO:0097484; P:dendrite extension; IDA:MGI.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IDA:MGI.
DR   GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SL9A7_HUMAN             Reviewed;         725 AA.
AC   Q96T83; O75827; Q5JXP9;
DE   RecName: Full=Sodium/hydrogen exchanger 7;
DE   AltName: Full=Na(+)/H(+) exchanger 7;
DE            Short=NHE-7;
DE   AltName: Full=Solute carrier family 9 member 7;
GN   Name=SLC9A7; Synonyms=NHE7;
DR   GO; GO:0015386; F:potassium:proton antiporter activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006885; P:regulation of pH; IDA:UniProtKB.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9A8_HUMAN             Reviewed;         581 AA.
AC   Q9Y2E8; B4DTQ8; Q2M1U9; Q68CZ8; Q9BX15; Q9Y507;
DE   RecName: Full=Sodium/hydrogen exchanger 8;
DE   AltName: Full=Na(+)/H(+) exchanger 8;
DE            Short=NHE-8;
DE   AltName: Full=Solute carrier family 9 member 8;
GN   Name=SLC9A8; Synonyms=KIAA0939, NHE8;
DR   GO; GO:0015386; F:potassium:proton antiporter activity; IEA:Ensembl.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0051453; P:regulation of intracellular pH; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9A9_HUMAN             Reviewed;         645 AA.
AC   Q8IVB4; A6NMQ9; Q3LIC2; Q5JPI6; Q5WA58; Q8NAB9;
DE   RecName: Full=Sodium/hydrogen exchanger 9;
DE   AltName: Full=Na(+)/H(+) exchanger 9;
DE            Short=NHE-9;
DE   AltName: Full=Solute carrier family 9 member 9;
GN   Name=SLC9A9; Synonyms=NHE9; ORFNames=Nbla00118;
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9B1_HUMAN             Reviewed;         515 AA.
AC   Q4ZJI4; A1KXV1; B9EH04; C9JBP7; Q49A30; Q8NCV2; Q8WVZ0;
DE   RecName: Full=Sodium/hydrogen exchanger 9B1;
DE   AltName: Full=Na(+)/H(+) exchanger-like domain-containing protein 1;
DE            Short=NHE domain-containing protein 1;
DE   AltName: Full=Sodium/hydrogen exchanger-like domain-containing protein 1;
DE   AltName: Full=Solute carrier family 9 subfamily B member 1;
GN   Name=SLC9B1; Synonyms=NHEDC1;
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9B2_HUMAN             Reviewed;         537 AA.
AC   Q86UD5; B5ME52; Q6ZMD8; Q96D95;
DE   RecName: Full=Mitochondrial sodium/hydrogen exchanger 9B2;
DE   AltName: Full=Mitochondrial Na(+)/H(+) exchanger NHA2;
DE   AltName: Full=Na(+)/H(+) exchanger-like domain-containing protein 2;
DE            Short=NHE domain-containing protein 2;
DE   AltName: Full=Sodium/hydrogen exchanger-like domain-containing protein 2;
DE   AltName: Full=Solute carrier family 9 subfamily B member 2;
GN   Name=SLC9B2; Synonyms=NHA2, NHEDC2;
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9C1_HUMAN             Reviewed;        1177 AA.
AC   Q4G0N8; Q6ZRP4; Q7RTP2;
DE   RecName: Full=Sodium/hydrogen exchanger 10;
DE   AltName: Full=Na(+)/H(+) exchanger 10;
DE            Short=NHE-10;
DE   AltName: Full=Solute carrier family 9 member 10;
DE   AltName: Full=Solute carrier family 9 member C1;
DE   AltName: Full=Sperm-specific Na(+)/H(+) exchanger;
DE            Short=sNHE;
GN   Name=SLC9C1; Synonyms=SLC9A10;
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SL9C2_HUMAN             Reviewed;        1124 AA.
AC   Q5TAH2; Q86UF3;
DE   RecName: Full=Sodium/hydrogen exchanger 11;
DE   AltName: Full=Na(+)/H(+) exchanger 11;
DE            Short=NHE-11;
DE   AltName: Full=Solute carrier family 9 member 11;
DE   AltName: Full=Solute carrier family 9 member C2;
GN   Name=SLC9C2; Synonyms=SLC9A11;
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
//
ID   SL9P1_HUMAN             Reviewed;         282 AA.
AC   A6NJY1;
DE   RecName: Full=Putative SLC9B1-like protein SLC9B1P1;
DE   AltName: Full=Solute carrier family 9 subfamily B member 1 pseudogene 1;
GN   Name=SLC9B1P1;
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
//
ID   SLAF1_HUMAN             Reviewed;         335 AA.
AC   Q13291; Q5W172; Q9HBE8;
DE   RecName: Full=Signaling lymphocytic activation molecule;
DE   AltName: Full=CDw150;
DE   AltName: Full=IPO-3;
DE   AltName: CD_antigen=CD150;
DE   Flags: Precursor;
GN   Name=SLAMF1; Synonyms=SLAM;
DR   GO; GO:0003823; F:antigen binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0046649; P:lymphocyte activation; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SLAF5_HUMAN             Reviewed;         345 AA.
AC   Q9UIB8; B2R8T1; B7Z3R8; O15430; O95266; O95660; Q5H9R1; Q6FHA8;
AC   Q8WLP1; Q8WWI8; Q9UF04; Q9UIB6; Q9UIB7; Q9UIT7;
DE   RecName: Full=SLAM family member 5;
DE   AltName: Full=Cell surface antigen MAX.3;
DE   AltName: Full=Hly9-beta;
DE   AltName: Full=Leukocyte differentiation antigen CD84;
DE   AltName: Full=Signaling lymphocytic activation molecule 5;
DE   AltName: CD_antigen=CD84;
DE   Flags: Precursor;
GN   Name=CD84; Synonyms=SLAMF5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
//
ID   SLAF6_HUMAN             Reviewed;         332 AA.
AC   Q96DU3; A6NMW2; B2R8X8; Q14CF0; Q5TAS4; Q5TAS6; Q5TAT3; Q96DV0;
DE   RecName: Full=SLAM family member 6;
DE   AltName: Full=Activating NK receptor;
DE   AltName: Full=NK-T-B-antigen;
DE            Short=NTB-A;
DE   AltName: CD_antigen=CD352;
DE   Flags: Precursor;
GN   Name=SLAMF6; Synonyms=KALI; ORFNames=UNQ6123/PRO20080;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
//
ID   SLAF7_HUMAN             Reviewed;         335 AA.
AC   Q9NQ25; A8K3U1; B4DPY3; Q8N6Y8; Q8ND32; Q9NY08; Q9NY23;
DE   RecName: Full=SLAM family member 7;
DE   AltName: Full=CD2 subset 1;
DE   AltName: Full=CD2-like receptor-activating cytotoxic cells;
DE            Short=CRACC;
DE   AltName: Full=Membrane protein FOAP-12;
DE   AltName: Full=Novel Ly9;
DE   AltName: Full=Protein 19A;
DE   AltName: CD_antigen=CD319;
DE   Flags: Precursor;
GN   Name=SLAMF7; Synonyms=CS1; ORFNames=UNQ576/PRO1138;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0030101; P:natural killer cell activation; NAS:UniProtKB.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; NAS:UniProtKB.
DR   GO; GO:0032814; P:regulation of natural killer cell activation; IEA:Ensembl.
//
ID   SLAF8_HUMAN             Reviewed;         285 AA.
AC   Q9P0V8; Q32MC6; Q5VU15;
DE   RecName: Full=SLAM family member 8;
DE   AltName: Full=B-lymphocyte activator macrophage expressed;
DE   AltName: Full=BCM-like membrane protein;
DE   AltName: CD_antigen=CD353;
DE   Flags: Precursor;
GN   Name=SLAMF8; Synonyms=BLAME;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0090383; P:phagosome acidification; IEA:Ensembl.
DR   GO; GO:0043549; P:regulation of kinase activity; IEA:Ensembl.
DR   GO; GO:0033860; P:regulation of NAD(P)H oxidase activity; IEA:Ensembl.
//
ID   SLAF9_HUMAN             Reviewed;         289 AA.
AC   Q96A28; Q5JRQ9; Q5JRR0; Q6UWG1;
DE   RecName: Full=SLAM family member 9;
DE   AltName: Full=CD2 family member 10;
DE            Short=CD2F-10;
DE   AltName: Full=CD84 homolog 1;
DE            Short=CD84-H1;
DE   Flags: Precursor;
GN   Name=SLAMF9; Synonyms=CD2F10; ORFNames=UNQ1938/PRO4421;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
//
ID   SLAI1_HUMAN             Reviewed;         568 AA.
AC   Q8ND83; A8K0Z9; B7Z209; Q5T6P4; Q5T6P7; Q8ND10; Q96NV0;
DE   RecName: Full=SLAIN motif-containing protein 1;
GN   Name=SLAIN1; Synonyms=C13orf32;
//
ID   SLAI2_HUMAN             Reviewed;         581 AA.
AC   Q9P270; A8K4P1; Q8N5R3;
DE   RecName: Full=SLAIN motif-containing protein 2;
GN   Name=SLAIN2; Synonyms=KIAA1458;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IMP:UniProtKB.
DR   GO; GO:0007020; P:microtubule nucleation; IMP:UniProtKB.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IMP:UniProtKB.
//
ID   SLAP1_HUMAN             Reviewed;         276 AA.
AC   Q13239; Q9UMQ8;
DE   RecName: Full=Src-like-adapter;
DE   AltName: Full=Src-like-adapter protein 1;
DE            Short=SLAP-1;
DE            Short=hSLAP;
GN   Name=SLA; Synonyms=SLAP, SLAP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
//
ID   SLAP2_HUMAN             Reviewed;         261 AA.
AC   Q9H6Q3; A8K648; E1P5U1; E1P5U2; Q5TH27; Q5TH28; Q8WY18; Q96QI4;
AC   Q9H135;
DE   RecName: Full=Src-like-adapter 2;
DE   AltName: Full=Modulator of antigen receptor signaling;
DE            Short=MARS;
DE   AltName: Full=Src-like adapter protein 2;
DE            Short=SLAP-2;
GN   Name=SLA2; Synonyms=C20orf156, SLAP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; IDA:UniProtKB.
DR   GO; GO:0050851; P:antigen receptor-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0019724; P:B cell mediated immunity; TAS:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0050869; P:negative regulation of B cell activation; TAS:UniProtKB.
DR   GO; GO:0050849; P:negative regulation of calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IDA:GOC.
DR   GO; GO:0050776; P:regulation of immune response; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
//
ID   SLBP_HUMAN              Reviewed;         270 AA.
AC   Q14493; B3KRJ5;
DE   RecName: Full=Histone RNA hairpin-binding protein;
DE   AltName: Full=Histone stem-loop-binding protein;
GN   Name=SLBP; Synonyms=HBP;
DR   GO; GO:0071208; F:histone pre-mRNA DCP binding; ISS:UniProtKB.
DR   GO; GO:0071207; F:histone pre-mRNA stem-loop binding; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006398; P:histone mRNA 3'-end processing; ISS:UniProtKB.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IDA:UniProtKB.
DR   GO; GO:0033260; P:nuclear cell cycle DNA replication; IMP:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SLC31_HUMAN             Reviewed;         685 AA.
AC   Q07837; A8K0S1; O00658; Q15295; Q4J6B4; Q4J6B5; Q4J6B6; Q4J6B7;
AC   Q4J6B8; Q4J6B9; Q52M92; Q52M94;
DE   RecName: Full=Neutral and basic amino acid transport protein rBAT;
DE            Short=NBAT;
DE   AltName: Full=D2h;
DE   AltName: Full=Solute carrier family 3 member 1;
DE   AltName: Full=b(0,+)-type amino acid transport protein;
GN   Name=SLC3A1; Synonyms=RBAT;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015174; F:basic amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0015184; F:L-cystine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003333; P:amino acid transmembrane transport; TAS:GOC.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0015802; P:basic amino acid transport; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015811; P:L-cystine transport; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SLD5_HUMAN              Reviewed;         223 AA.
AC   Q9BRT9; B2R8H5; D3DSY0; Q8N648;
DE   RecName: Full=DNA replication complex GINS protein SLD5;
DE   AltName: Full=GINS complex subunit 4;
DE   Contains:
DE     RecName: Full=DNA replication complex GINS protein SLD5, N-terminally processed;
GN   Name=GINS4; Synonyms=SLD5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006271; P:DNA strand elongation involved in DNA replication; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   SLFN5_HUMAN             Reviewed;         891 AA.
AC   Q08AF3; Q08AF2; Q8WU54; Q96A82;
DE   RecName: Full=Schlafen family member 5;
GN   Name=SLFN5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   SLIB_HUMAN              Reviewed;         108 AA.
AC   P01286; Q4KN10; Q5JYR1;
DE   RecName: Full=Somatoliberin;
DE   AltName: Full=Growth hormone-releasing factor;
DE            Short=GRF;
DE   AltName: Full=Growth hormone-releasing hormone;
DE            Short=GHRH;
DE   AltName: Full=Somatocrinin;
DE   AltName: Full=Somatorelin;
DE   AltName: INN=Sermorelin;
DE   Flags: Precursor;
GN   Name=GHRH; Synonyms=GHRF;
DR   GO; GO:0016608; F:growth hormone-releasing hormone activity; IDA:BHF-UCL.
DR   GO; GO:0031770; F:growth hormone-releasing hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0021984; P:adenohypophysis development; ISS:BHF-UCL.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0030252; P:growth hormone secretion; IDA:MGI.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0046005; P:positive regulation of circadian sleep/wake cycle, REM sleep; NAS:BHF-UCL.
DR   GO; GO:0060124; P:positive regulation of growth hormone secretion; IDA:BHF-UCL.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IMP:BHF-UCL.
DR   GO; GO:0032094; P:response to food; ISS:BHF-UCL.
//
ID   SLIK1_HUMAN             Reviewed;         696 AA.
AC   Q96PX8; Q5U5I6; Q96SF9;
DE   RecName: Full=SLIT and NTRK-like protein 1;
DE   AltName: Full=Leucine-rich repeat-containing protein 12;
DE   Flags: Precursor;
GN   Name=SLITRK1; Synonyms=KIAA1910, LRRC12; ORFNames=UNQ233/PRO266;
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0042592; P:homeostatic process; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
//
ID   SLIK2_HUMAN             Reviewed;         845 AA.
AC   Q9H156; A8K117; Q2KHN3; Q5JXB1; Q8NBC7; Q96JH3;
DE   RecName: Full=SLIT and NTRK-like protein 2;
DE   Flags: Precursor;
GN   Name=SLITRK2; Synonyms=CXorf2, KIAA1854, SLITL1;
GN   ORFNames=UNQ9197/PRO34756;
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
//
ID   SLIK3_HUMAN             Reviewed;         977 AA.
AC   O94933; Q1RMY6;
DE   RecName: Full=SLIT and NTRK-like protein 3;
DE   Flags: Precursor;
GN   Name=SLITRK3; Synonyms=KIAA0848;
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
//
ID   SLIK4_HUMAN             Reviewed;         837 AA.
AC   Q8IW52; Q5JXG3; Q8TCM8; Q96DL3;
DE   RecName: Full=SLIT and NTRK-like protein 4;
DE   Flags: Precursor;
GN   Name=SLITRK4;
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
//
ID   SLIK5_HUMAN             Reviewed;         958 AA.
AC   O94991; B3KNB8; Q5VT81;
DE   RecName: Full=SLIT and NTRK-like protein 5;
DE   AltName: Full=Leucine-rich repeat-containing protein 11;
DE   Flags: Precursor;
GN   Name=SLITRK5; Synonyms=KIAA0918, LRRC11;
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0072358; P:cardiovascular system development; IEA:Ensembl.
DR   GO; GO:0048813; P:dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0009410; P:response to xenobiotic stimulus; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0021756; P:striatum development; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   SLIK6_HUMAN             Reviewed;         841 AA.
AC   Q9H5Y7; A8K9S8; Q495Q0; Q6AW93; Q9HAA8; Q9NT60;
DE   RecName: Full=SLIT and NTRK-like protein 6;
DE   Flags: Precursor;
GN   Name=SLITRK6;
DR   GO; GO:0002093; P:auditory receptor cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0090102; P:cochlea development; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
DR   GO; GO:0001964; P:startle response; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; IMP:MGI.
DR   GO; GO:0060005; P:vestibular reflex; IEA:Ensembl.
DR   GO; GO:0021562; P:vestibulocochlear nerve development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   SLIRP_HUMAN             Reviewed;         109 AA.
AC   Q9GZT3; J3KMY7;
DE   RecName: Full=SRA stem-loop-interacting RNA-binding protein, mitochondrial;
DE   Flags: Precursor;
GN   Name=SLIRP; Synonyms=C14orf156; ORFNames=DC23, DC50, PD04872;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000961; P:negative regulation of mitochondrial RNA catabolic process; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SLIP_HUMAN              Reviewed;         796 AA.
AC   Q68CJ6; Q6ZP73;
DE   RecName: Full=Nuclear GTPase SLIP-GC;
DE            EC=3.6.1.-;
DE   AltName: Full=Speckled-like pattern in the germinal center;
GN   Name=NUGGC; Synonyms=C8orf80; ORFNames=HMFN0672;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Ensembl.
//
ID   SLIT1_HUMAN             Reviewed;        1534 AA.
AC   O75093; Q5T0V1; Q8WWZ2; Q9UIL7;
DE   RecName: Full=Slit homolog 1 protein;
DE            Short=Slit-1;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 4;
DE            Short=Multiple EGF-like domains protein 4;
DE   Flags: Precursor;
GN   Name=SLIT1; Synonyms=KIAA0813, MEGF4, SLIL1;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0048495; F:Roundabout binding; IPI:UniProtKB.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IDA:UniProtKB.
DR   GO; GO:0033563; P:dorsal/ventral axon guidance; IEA:Ensembl.
DR   GO; GO:0040023; P:establishment of nucleus localization; IEA:Ensembl.
DR   GO; GO:0048853; P:forebrain morphogenesis; NAS:UniProtKB.
DR   GO; GO:0008045; P:motor neuron axon guidance; IMP:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0051964; P:negative regulation of synapse assembly; ISS:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IEA:Ensembl.
//
ID   SLIT2_HUMAN             Reviewed;        1529 AA.
AC   O94813; B7ZLR5; O95710; Q17RU3; Q9Y5Q7;
DE   RecName: Full=Slit homolog 2 protein;
DE            Short=Slit-2;
DE   Contains:
DE     RecName: Full=Slit homolog 2 protein N-product;
DE   Contains:
DE     RecName: Full=Slit homolog 2 protein C-product;
DE   Flags: Precursor;
GN   Name=SLIT2; Synonyms=SLIL3;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0045499; F:chemorepellent activity; IEA:Ensembl.
DR   GO; GO:0005095; F:GTPase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0043237; F:laminin-1 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043394; F:proteoglycan binding; IPI:UniProtKB.
DR   GO; GO:0048495; F:Roundabout binding; IPI:UniProtKB.
DR   GO; GO:0061364; P:apoptotic process involved in luteolysis; IEP:UniProtKB.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IDA:UniProtKB.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IDA:UniProtKB.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0071504; P:cellular response to heparin; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0021836; P:chemorepulsion involved in postnatal olfactory bulb interneuron migration; IDA:UniProtKB.
DR   GO; GO:0021972; P:corticospinal neuron axon guidance through spinal cord; IMP:BHF-UCL.
DR   GO; GO:0033563; P:dorsal/ventral axon guidance; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0050929; P:induction of negative chemotaxis; IDA:UniProtKB.
DR   GO; GO:0060763; P:mammary duct terminal end bud growth; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0008045; P:motor neuron axon guidance; IDA:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0090288; P:negative regulation of cellular response to growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0070100; P:negative regulation of chemokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0010593; P:negative regulation of lamellipodium assembly; IDA:UniProtKB.
DR   GO; GO:0002689; P:negative regulation of leukocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0090027; P:negative regulation of monocyte chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0071676; P:negative regulation of mononuclear cell migration; IDA:BHF-UCL.
DR   GO; GO:0090024; P:negative regulation of neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0090260; P:negative regulation of retinal ganglion cell axon guidance; IDA:UniProtKB.
DR   GO; GO:0051058; P:negative regulation of small GTPase mediated signal transduction; IDA:UniProtKB.
DR   GO; GO:0071672; P:negative regulation of smooth muscle cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; TAS:UniProtKB.
DR   GO; GO:0051414; P:response to cortisol; IEP:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IDA:UniProtKB.
DR   GO; GO:0035385; P:Roundabout signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; IMP:UniProtKB.
//
ID   SLIT3_HUMAN             Reviewed;        1523 AA.
AC   O75094; A6H8U9; J3KNP3; O95804; Q9UFH5;
DE   RecName: Full=Slit homolog 3 protein;
DE            Short=Slit-3;
DE   AltName: Full=Multiple epidermal growth factor-like domains protein 5;
DE            Short=Multiple EGF-like domains protein 5;
DE   Flags: Precursor;
GN   Name=SLIT3; Synonyms=KIAA0814, MEGF5, SLIL2; ORFNames=UNQ691/PRO1336;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048495; F:Roundabout binding; IPI:UniProtKB.
DR   GO; GO:0061364; P:apoptotic process involved in luteolysis; IEP:UniProtKB.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IDA:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEP:UniProtKB.
DR   GO; GO:0050919; P:negative chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070100; P:negative regulation of chemokine-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0051414; P:response to cortisol; IEP:UniProtKB.
DR   GO; GO:0035385; P:Roundabout signaling pathway; IMP:BHF-UCL.
//
ID   SLK_HUMAN               Reviewed;        1235 AA.
AC   Q9H2G2; D3DRA0; D3DRA1; O00211; Q6P1Z4; Q86WU7; Q86WW1; Q92603;
AC   Q9NQL0; Q9NQL1;
DE   RecName: Full=STE20-like serine/threonine-protein kinase;
DE            Short=STE20-like kinase;
DE            Short=hSLK;
DE            EC=2.7.11.1;
DE   AltName: Full=CTCL tumor antigen se20-9;
DE   AltName: Full=STE20-related serine/threonine-protein kinase;
DE            Short=STE20-related kinase;
DE   AltName: Full=Serine/threonine-protein kinase 2;
GN   Name=SLK; Synonyms=KIAA0204, STK2;
DR   GuidetoPHARMACOLOGY; 2200; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   SLMAP_HUMAN             Reviewed;         828 AA.
AC   Q14BN4; Q14C95; Q6AI54; Q6UXC9; Q6ZVQ8; Q8NCW9; Q9H297; Q9HCH1;
AC   Q9Y681;
DE   RecName: Full=Sarcolemmal membrane-associated protein;
DE            Short=Sarcolemmal-associated protein;
GN   Name=SLMAP; Synonyms=KIAA1601, SLAP; ORFNames=UNQ1847/PRO3577;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   SLMO1_HUMAN             Reviewed;         172 AA.
AC   Q96N28; B0YJ10; D3DUJ1; Q6AHX2;
DE   RecName: Full=Protein slowmo homolog 1;
GN   Name=SLMO1; Synonyms=C18orf43;
DR   GO; GO:1990050; F:phosphatidic acid transporter activity; IBA:RefGenome.
DR   GO; GO:0015914; P:phospholipid transport; IBA:RefGenome.
//
ID   SLMO2_HUMAN             Reviewed;         194 AA.
AC   Q9Y3B1; E1P5I8; Q5JX17; Q9NUL0;
DE   RecName: Full=Protein slowmo homolog 2;
GN   Name=SLMO2; Synonyms=C20orf45; ORFNames=CGI-107;
DR   GO; GO:1990050; F:phosphatidic acid transporter activity; IBA:RefGenome.
DR   GO; GO:0015914; P:phospholipid transport; IBA:RefGenome.
//
ID   SLN14_HUMAN             Reviewed;         912 AA.
AC   P0C7P3; B2RTW9;
DE   RecName: Full=Schlafen family member 14;
GN   Name=SLFN14;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   SLN13_HUMAN             Reviewed;         897 AA.
AC   Q68D06; E1P645; Q658M1; Q6ZS51; Q96A81;
DE   RecName: Full=Schlafen family member 13;
GN   Name=SLFN13;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   SLN12_HUMAN             Reviewed;         578 AA.
AC   Q8IYM2; A8K711; Q9NP47;
DE   RecName: Full=Schlafen family member 12;
GN   Name=SLFN12;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
//
ID   SLN11_HUMAN             Reviewed;         901 AA.
AC   Q7Z7L1; E1P643; Q8N3S8; Q8N762; Q8TEE0;
DE   RecName: Full=Schlafen family member 11;
GN   Name=SLFN11;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.
//
ID   SLNL1_HUMAN             Reviewed;         407 AA.
AC   Q499Z3; A8K8D1; Q49AG8; Q5VW72; Q5VW74; Q8N7V7; Q8TCH6; Q8WVZ8;
DE   RecName: Full=Schlafen-like protein 1;
GN   Name=SLFNL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
//
ID   SLPI_HUMAN              Reviewed;         132 AA.
AC   P03973; B2R5H8; P07757;
DE   RecName: Full=Antileukoproteinase;
DE            Short=ALP;
DE   AltName: Full=BLPI;
DE   AltName: Full=HUSI-1;
DE   AltName: Full=Mucus proteinase inhibitor;
DE            Short=MPI;
DE   AltName: Full=Protease inhibitor WAP4;
DE   AltName: Full=Secretory leukocyte protease inhibitor;
DE   AltName: Full=Seminal proteinase inhibitor;
DE   AltName: Full=WAP four-disulfide core domain protein 4;
DE   Flags: Precursor;
GN   Name=SLPI; Synonyms=WAP4, WFDC4;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
//
ID   SLTM_HUMAN              Reviewed;        1034 AA.
AC   Q9NWH9; B2RTX3; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3;
AC   Q9H8U9;
DE   RecName: Full=SAFB-like transcription modulator;
DE   AltName: Full=Modulator of estrogen-induced transcription;
GN   Name=SLTM; Synonyms=MET;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SLU7_HUMAN              Reviewed;         586 AA.
AC   O95391; D3DQK2; Q3LUJ0; Q3LUJ1; Q6RXQ5; Q96FM9;
DE   RecName: Full=Pre-mRNA-splicing factor SLU7;
DE            Short=hSlu7;
GN   Name=SLU7;
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000386; F:second spliceosomal transesterification activity; IDA:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IDA:HGNC.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IDA:HGNC.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0000389; P:mRNA 3'-splice site recognition; IDA:HGNC.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; IDA:HGNC.
//
ID   SLUR1_HUMAN             Reviewed;         103 AA.
AC   P55000; Q53YJ6; Q6PUA6; Q92483;
DE   RecName: Full=Secreted Ly-6/uPAR-related protein 1;
DE            Short=SLURP-1;
DE   AltName: Full=ARS component B;
DE   AltName: Full=ARS(component B)-81/S;
DE   AltName: Full=Anti-neoplastic urinary protein;
DE            Short=ANUP;
DE   Flags: Precursor;
GN   Name=SLURP1; Synonyms=ARS;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0001775; P:cell activation; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
//
ID   SLX1_HUMAN              Reviewed;         275 AA.
AC   Q9BQ83; B7ZME1; Q6NTG6;
DE   RecName: Full=Structure-specific endonuclease subunit SLX1;
DE            EC=3.6.1.-;
DE   AltName: Full=GIY-YIG domain-containing protein 1;
GN   Name=SLX1A; Synonyms=GIYD1, SLX1;
GN   and
GN   Name=SLX1B; Synonyms=GIYD2, SLX1;
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IDA:UniProtKB.
DR   GO; GO:0008821; F:crossover junction endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0010792; P:DNA double-strand break processing involved in repair via single-strand annealing; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
//
ID   SLX4I_HUMAN             Reviewed;         408 AA.
AC   Q5VYV7; Q05CG2; Q05CT9;
DE   RecName: Full=Protein SLX4IP;
DE   AltName: Full=SLX4-interacting protein;
GN   Name=SLX4IP; Synonyms=C20orf94;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   SLX4_HUMAN              Reviewed;        1834 AA.
AC   Q8IY92; Q69YT8; Q8TF15; Q96JP1;
DE   RecName: Full=Structure-specific endonuclease subunit SLX4;
DE   AltName: Full=BTB/POZ domain-containing protein 12;
GN   Name=SLX4; Synonyms=BTBD12, KIAA1784, KIAA1987;
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0010792; P:DNA double-strand break processing involved in repair via single-strand annealing; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
//
ID   SMAD3_HUMAN             Reviewed;         425 AA.
AC   P84022; A8K4B6; B7Z4Z5; B7Z6M9; B7Z9Q2; F5H383; O09064; O09144;
AC   O14510; O35273; Q92940; Q93002; Q9GKR4;
DE   RecName: Full=Mothers against decapentaplegic homolog 3;
DE            Short=MAD homolog 3;
DE            Short=Mad3;
DE            Short=Mothers against DPP homolog 3;
DE            Short=hMAD-3;
DE   AltName: Full=JV15-2;
DE   AltName: Full=SMAD family member 3;
DE            Short=SMAD 3;
DE            Short=Smad3;
DE            Short=hSMAD3;
GN   Name=SMAD3; Synonyms=MADH3;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; IPI:BHF-UCL.
DR   GO; GO:0030618; F:transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; IDA:BHF-UCL.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0097296; P:activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0045216; P:cell-cell junction organization; IMP:BHF-UCL.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0019049; P:evasion or tolerance of host defenses by virus; IDA:BHF-UCL.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IMP:BHF-UCL.
DR   GO; GO:0002520; P:immune system development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:GOC.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0033689; P:negative regulation of osteoblast proliferation; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0061045; P:negative regulation of wound healing; IEA:Ensembl.
DR   GO; GO:0038092; P:nodal signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002076; P:osteoblast development; IEA:Ensembl.
DR   GO; GO:0048340; P:paraxial mesoderm morphogenesis; IEA:Ensembl.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0010694; P:positive regulation of alkaline phosphatase activity; IEA:Ensembl.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:1901313; P:positive regulation of gene expression involved in extracellular matrix organization; IMP:BHF-UCL.
DR   GO; GO:0032731; P:positive regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0032916; P:positive regulation of transforming growth factor beta3 production; IEA:Ensembl.
DR   GO; GO:0031053; P:primary miRNA processing; TAS:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IMP:BHF-UCL.
DR   GO; GO:0051098; P:regulation of binding; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0032909; P:regulation of transforming growth factor beta2 production; IMP:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0060290; P:transdifferentiation; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006810; P:transport; IDA:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; TAS:BHF-UCL.
//
ID   SMA5O_HUMAN             Reviewed;          95 AA.
AC   Q9Y6J3;
DE   RecName: Full=SMAD5 antisense gene protein 1;
DE   AltName: Full=10.3 kDa proline-rich protein DAMS;
DE   AltName: Full=SMAD5 antisense RNA 1;
DE   AltName: Full=SMAD5 opposite strand protein;
GN   Name=SMAD5-AS1; Synonyms=DAMS, SMAD5OS;
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SMAD2_HUMAN             Reviewed;         467 AA.
AC   Q15796;
DE   RecName: Full=Mothers against decapentaplegic homolog 2;
DE            Short=MAD homolog 2;
DE            Short=Mothers against DPP homolog 2;
DE   AltName: Full=JV18-1;
DE   AltName: Full=Mad-related protein 2;
DE            Short=hMAD-2;
DE   AltName: Full=SMAD family member 2;
DE            Short=SMAD 2;
DE            Short=Smad2;
DE            Short=hSMAD2;
GN   Name=SMAD2; Synonyms=MADH2, MADR2;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0003690; F:double-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019902; F:phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; IPI:BHF-UCL.
DR   GO; GO:0030618; F:transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; IDA:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0032924; P:activin receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IDA:MGI.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; IEA:Ensembl.
DR   GO; GO:0001706; P:endoderm formation; IEA:Ensembl.
DR   GO; GO:0007369; P:gastrulation; TAS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038092; P:nodal signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035265; P:organ growth; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0031016; P:pancreas development; IEA:Ensembl.
DR   GO; GO:0048340; P:paraxial mesoderm morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060039; P:pericardium development; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:1900224; P:positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0031053; P:primary miRNA processing; TAS:BHF-UCL.
DR   GO; GO:0051098; P:regulation of binding; ISS:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0070723; P:response to cholesterol; IDA:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0007352; P:zygotic specification of dorsal/ventral axis; IMP:BHF-UCL.
//
ID   SMAD4_HUMAN             Reviewed;         552 AA.
AC   Q13485; A8K405;
DE   RecName: Full=Mothers against decapentaplegic homolog 4;
DE            Short=MAD homolog 4;
DE            Short=Mothers against DPP homolog 4;
DE   AltName: Full=Deletion target in pancreatic carcinoma 4;
DE   AltName: Full=SMAD family member 4;
DE            Short=SMAD 4;
DE            Short=Smad4;
DE            Short=hSMAD4;
GN   Name=SMAD4; Synonyms=DPC4, MADH4;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0030616; F:transforming growth factor beta receptor, common-partner cytoplasmic mediator activity; IDA:BHF-UCL.
DR   GO; GO:0036302; P:atrioventricular canal development; IEA:Ensembl.
DR   GO; GO:0003190; P:atrioventricular valve formation; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0003360; P:brainstem development; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0003279; P:cardiac septum development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0060956; P:endocardial cell differentiation; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0042118; P:endothelial cell activation; IEA:Ensembl.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; IEA:Ensembl.
DR   GO; GO:0048859; P:formation of anatomical boundary; IEA:Ensembl.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:GOC.
DR   GO; GO:0007498; P:mesoderm development; IEA:Ensembl.
DR   GO; GO:0072133; P:metanephric mesenchyme morphogenesis; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0072134; P:nephrogenic mesenchyme morphogenesis; IEA:Ensembl.
DR   GO; GO:0014033; P:neural crest cell differentiation; IEA:Ensembl.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0003251; P:positive regulation of cell proliferation involved in heart valve morphogenesis; IEA:Ensembl.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051098; P:regulation of binding; IEA:Ensembl.
DR   GO; GO:0051797; P:regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0032909; P:regulation of transforming growth factor beta2 production; IMP:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0071559; P:response to transforming growth factor beta; IDA:UniProtKB.
DR   GO; GO:0048733; P:sebaceous gland development; IEA:Ensembl.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0060395; P:SMAD protein signal transduction; IDA:BHF-UCL.
DR   GO; GO:0032525; P:somite rostral/caudal axis specification; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
//
ID   SMAD1_HUMAN             Reviewed;         465 AA.
AC   Q15797; A8KAJ0; D3DNZ9; Q16636;
DE   RecName: Full=Mothers against decapentaplegic homolog 1;
DE            Short=MAD homolog 1;
DE            Short=Mothers against DPP homolog 1;
DE   AltName: Full=JV4-1;
DE   AltName: Full=Mad-related protein 1;
DE   AltName: Full=SMAD family member 1;
DE            Short=SMAD 1;
DE            Short=Smad1;
DE            Short=hSMAD1;
DE   AltName: Full=Transforming growth factor-beta-signaling protein 1;
DE            Short=BSP-1;
GN   Name=SMAD1; Synonyms=BSP1, MADH1, MADR1;
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0030618; F:transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; TAS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; ISS:BHF-UCL.
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0042592; P:homeostatic process; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IEA:Ensembl.
DR   GO; GO:0001710; P:mesodermal cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010656; P:negative regulation of muscle cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0002051; P:osteoblast fate commitment; IEA:Ensembl.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.
DR   GO; GO:1901522; P:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; ISS:BHF-UCL.
DR   GO; GO:0031053; P:primary miRNA processing; TAS:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   SMAD5_HUMAN             Reviewed;         465 AA.
AC   Q99717; O14688; Q15798; Q9UQA1;
DE   RecName: Full=Mothers against decapentaplegic homolog 5;
DE            Short=MAD homolog 5;
DE            Short=Mothers against DPP homolog 5;
DE   AltName: Full=JV5-1;
DE   AltName: Full=SMAD family member 5;
DE            Short=SMAD 5;
DE            Short=Smad5;
DE            Short=hSmad5;
GN   Name=SMAD5; Synonyms=MADH5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; NAS:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030618; F:transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; TAS:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; ISS:BHF-UCL.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:GOC.
DR   GO; GO:0001880; P:Mullerian duct regression; IEA:Ensembl.
DR   GO; GO:0002051; P:osteoblast fate commitment; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:1901522; P:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   SMAD6_HUMAN             Reviewed;         496 AA.
AC   O43541; A9J6M5; O43654; Q15799; Q7Z7L4; Q96E31; Q9UKZ3;
DE   RecName: Full=Mothers against decapentaplegic homolog 6;
DE            Short=MAD homolog 6;
DE            Short=Mothers against DPP homolog 6;
DE   AltName: Full=SMAD family member 6;
DE            Short=SMAD 6;
DE            Short=Smad6;
DE            Short=hSMAD6;
GN   Name=SMAD6; Synonyms=MADH6;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0030617; F:transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; IDA:BHF-UCL.
DR   GO; GO:0070698; F:type I activin receptor binding; IDA:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0031589; P:cell-substrate adhesion; IMP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IMP:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0007352; P:zygotic specification of dorsal/ventral axis; IMP:BHF-UCL.
//
ID   SMAD7_HUMAN             Reviewed;         426 AA.
AC   O15105; B7Z773; K7EQ10; O14740; Q6DK23;
DE   RecName: Full=Mothers against decapentaplegic homolog 7;
DE            Short=MAD homolog 7;
DE            Short=Mothers against DPP homolog 7;
DE   AltName: Full=Mothers against decapentaplegic homolog 8;
DE            Short=MAD homolog 8;
DE            Short=Mothers against DPP homolog 8;
DE   AltName: Full=SMAD family member 7;
DE            Short=SMAD 7;
DE            Short=Smad7;
DE            Short=hSMAD7;
GN   Name=SMAD7; Synonyms=MADH7, MADH8;
DR   GO; GO:0048185; F:activin binding; IPI:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0030617; F:transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity; IDA:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; IPI:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0034333; P:adherens junction assembly; IMP:BHF-UCL.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0034629; P:cellular protein complex localization; IDA:BHF-UCL.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IMP:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; TAS:BHF-UCL.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; TAS:BHF-UCL.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0033137; P:negative regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051444; P:negative regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0032925; P:regulation of activin receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0055117; P:regulation of cardiac muscle contraction; ISS:BHF-UCL.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0060373; P:regulation of ventricular cardiac muscle cell membrane depolarization; IC:BHF-UCL.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEP:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   SMAD9_HUMAN             Reviewed;         467 AA.
AC   O15198; A2A2Y6; O14989; Q5TBA1;
DE   RecName: Full=Mothers against decapentaplegic homolog 9;
DE            Short=MAD homolog 9;
DE            Short=Mothers against DPP homolog 9;
DE   AltName: Full=Madh6;
DE   AltName: Full=SMAD family member 9;
DE            Short=SMAD 9;
DE            Short=Smad9;
GN   Name=SMAD9; Synonyms=MADH6, MADH9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030618; F:transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity; TAS:BHF-UCL.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0001880; P:Mullerian duct regression; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   SMAG1_HUMAN             Reviewed;         718 AA.
AC   Q9UPU9; A8MPZ5; Q0VA96; Q6PEW4;
DE   RecName: Full=Protein Smaug homolog 1;
DE            Short=Smaug 1;
DE            Short=hSmaug1;
DE   AltName: Full=Sterile alpha motif domain-containing protein 4A;
DE            Short=SAM domain-containing protein 4A;
GN   Name=SAMD4A; Synonyms=KIAA1053, SAMD4, SMAUG1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030371; F:translation repressor activity; IDA:MGI.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:GOC.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:MGI.
//
ID   SMAG2_HUMAN             Reviewed;         694 AA.
AC   Q5PRF9; A5Z0M6; Q6P194;
DE   RecName: Full=Protein Smaug homolog 2;
DE            Short=Smaug 2;
DE            Short=hSmaug2;
DE   AltName: Full=Sterile alpha motif domain-containing protein 4B;
DE            Short=SAM domain-containing protein 4B;
GN   Name=SAMD4B; Synonyms=SMAUG2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMAGP_HUMAN             Reviewed;          97 AA.
AC   Q0VAQ4; A6NIL5;
DE   RecName: Full=Small cell adhesion glycoprotein;
DE   AltName: Full=Small transmembrane and glycosylated protein;
GN   Name=SMAGP;
//
ID   SMAKA_HUMAN             Reviewed;          95 AA.
AC   Q9BSF0; D3DPI3; P0C876; Q53TC7;
DE   RecName: Full=Small membrane A-kinase anchor protein;
DE            Short=Small membrane AKAP;
DE            Short=smAKAP;
GN   Name=C2orf88;
//
ID   SMAP1_HUMAN             Reviewed;         467 AA.
AC   Q8IYB5; Q53H70; Q5SYQ2; Q6PK24; Q8NDH4; Q96L38; Q96L39; Q9H8X4;
DE   RecName: Full=Stromal membrane-associated protein 1;
GN   Name=SMAP1;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
DR   GO; GO:2000369; P:regulation of clathrin-mediated endocytosis; IEA:Ensembl.
//
ID   SMAL1_HUMAN             Reviewed;         954 AA.
AC   Q9NZC9; A6NEH0; Q53R00; Q96AY1; Q9NXQ5; Q9UFH3; Q9UI93;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1;
DE            EC=3.6.4.-;
DE   AltName: Full=HepA-related protein;
DE            Short=hHARP;
DE   AltName: Full=Sucrose nonfermenting protein 2-like 1;
GN   Name=SMARCAL1; Synonyms=HARP;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IMP:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:GOC.
DR   GO; GO:0016568; P:chromatin modification; IEA:InterPro.
DR   GO; GO:0006259; P:DNA metabolic process; IMP:UniProtKB.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
//
ID   SMAP_HUMAN              Reviewed;         183 AA.
AC   O00193; B2RD28;
DE   RecName: Full=Small acidic protein;
GN   Name=SMAP; Synonyms=C11orf58;
//
ID   SMAP2_HUMAN             Reviewed;         429 AA.
AC   Q8WU79; B2R7T1; B7Z5B5; B7Z8V2; D3DPV2; Q5QPL2; Q96C93; Q9NST2;
AC   Q9UJL8;
DE   RecName: Full=Stromal membrane-associated protein 2;
DE   AltName: Full=Stromal membrane-associated protein 1-like;
GN   Name=SMAP2; Synonyms=SMAP1L;
DR   GO; GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
//
ID   SMBP2_HUMAN             Reviewed;         993 AA.
AC   P38935; A0PJD2; Q00443; Q14177;
DE   RecName: Full=DNA-binding protein SMUBP-2;
DE            EC=3.6.4.12;
DE            EC=3.6.4.13;
DE   AltName: Full=ATP-dependent helicase IGHMBP2;
DE   AltName: Full=Glial factor 1;
DE            Short=GF-1;
DE   AltName: Full=Immunoglobulin mu-binding protein 2;
GN   Name=IGHMBP2; Synonyms=SMBP2, SMUBP2;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0032575; F:ATP-dependent 5'-3' RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0008186; F:RNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IPI:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
//
ID   SMBT1_HUMAN             Reviewed;         866 AA.
AC   Q9UHJ3; Q402F7; Q96C73; Q9Y4Q9;
DE   RecName: Full=Scm-like with four MBT domains protein 1;
DE            Short=hSFMBT;
DE   AltName: Full=Renal ubiquitous protein 1;
GN   Name=SFMBT1; Synonyms=RU1;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0048635; P:negative regulation of muscle organ development; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMBT2_HUMAN             Reviewed;         894 AA.
AC   Q5VUG0; A7MD09; Q9HCF5;
DE   RecName: Full=Scm-like with four MBT domains protein 2;
DE            Short=Scm-like with 4 MBT domains protein 2;
GN   Name=SFMBT2; Synonyms=KIAA1617;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   SMC1B_HUMAN             Reviewed;        1235 AA.
AC   Q8NDV3; A0AV46; B0QY23; B0QY24; Q5TIC3; Q6ZUF9; Q9Y3G5;
DE   RecName: Full=Structural maintenance of chromosomes protein 1B;
DE            Short=SMC protein 1B;
DE            Short=SMC-1-beta;
DE            Short=SMC-1B;
GN   Name=SMC1B; Synonyms=SMC1L2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:Ensembl.
//
ID   SMC1A_HUMAN             Reviewed;        1233 AA.
AC   Q14683; O14995; Q16351; Q2M228;
DE   RecName: Full=Structural maintenance of chromosomes protein 1A;
DE            Short=SMC protein 1A;
DE            Short=SMC-1-alpha;
DE            Short=SMC-1A;
DE   AltName: Full=Sb1.8;
GN   Name=SMC1A; Synonyms=DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; TAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007126; P:meiotic nuclear division; ISS:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:UniProtKB.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; TAS:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; TAS:UniProtKB.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.
DR   GO; GO:0009314; P:response to radiation; IEP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   SMC2_HUMAN              Reviewed;        1197 AA.
AC   O95347; Q6IEE0; Q9P1P2;
DE   RecName: Full=Structural maintenance of chromosomes protein 2;
DE            Short=SMC protein 2;
DE            Short=SMC-2;
DE   AltName: Full=Chromosome-associated protein E;
DE            Short=hCAP-E;
DE   AltName: Full=XCAP-E homolog;
GN   Name=SMC2; Synonyms=CAPE, SMC2L1; ORFNames=PRO0324;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0051383; P:kinetochore organization; IEA:Ensembl.
DR   GO; GO:0010032; P:meiotic chromosome condensation; IEA:Ensembl.
DR   GO; GO:0045132; P:meiotic chromosome segregation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
//
ID   SMC3_HUMAN              Reviewed;        1217 AA.
AC   Q9UQE7; A8K156; O60464; Q5T482;
DE   RecName: Full=Structural maintenance of chromosomes protein 3;
DE            Short=SMC protein 3;
DE            Short=SMC-3;
DE   AltName: Full=Basement membrane-associated chondroitin proteoglycan;
DE            Short=Bamacan;
DE   AltName: Full=Chondroitin sulfate proteoglycan 6;
DE   AltName: Full=Chromosome-associated polypeptide;
DE            Short=hCAP;
GN   Name=SMC3; Synonyms=BAM, BMH, CSPG6, SMC3L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0045502; F:dynein binding; IDA:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007052; P:mitotic spindle organization; IEP:UniProtKB.
DR   GO; GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.
DR   GO; GO:0006275; P:regulation of DNA replication; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007062; P:sister chromatid cohesion; NAS:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   SMC4_HUMAN              Reviewed;        1288 AA.
AC   Q9NTJ3; A6NLT9; D3DNL8; O95752; Q8NDL4; Q9UNT9;
DE   RecName: Full=Structural maintenance of chromosomes protein 4;
DE            Short=SMC protein 4;
DE            Short=SMC-4;
DE   AltName: Full=Chromosome-associated polypeptide C;
DE            Short=hCAP-C;
DE   AltName: Full=XCAP-C homolog;
GN   Name=SMC4; Synonyms=CAPC, SMC4L1;
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0051383; P:kinetochore organization; IEA:Ensembl.
DR   GO; GO:0010032; P:meiotic chromosome condensation; IEA:Ensembl.
DR   GO; GO:0045132; P:meiotic chromosome segregation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IDA:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; TAS:UniProtKB.
//
ID   SMC5_HUMAN              Reviewed;        1101 AA.
AC   Q8IY18; A6NM81; O60335; Q05D92; Q5VZ60; Q96SB9;
DE   RecName: Full=Structural maintenance of chromosomes protein 5;
DE            Short=SMC protein 5;
DE            Short=SMC-5;
DE            Short=hSMC5;
GN   Name=SMC5; Synonyms=KIAA0594, SMC5L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090398; P:cellular senescence; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0034184; P:positive regulation of maintenance of mitotic sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IMP:UniProtKB.
DR   GO; GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
//
ID   SMC6_HUMAN              Reviewed;        1091 AA.
AC   Q96SB8; A8K8Q6; D6W518; Q05BV4; Q9H0X3; Q9H6M0;
DE   RecName: Full=Structural maintenance of chromosomes protein 6;
DE            Short=SMC protein 6;
DE            Short=SMC-6;
DE            Short=hSMC6;
GN   Name=SMC6; Synonyms=SMC6L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090398; P:cellular senescence; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR   GO; GO:0000722; P:telomere maintenance via recombination; IMP:UniProtKB.
//
ID   SMCA1_HUMAN             Reviewed;        1054 AA.
AC   P28370; Q5JV41; Q5JV42;
DE   RecName: Full=Probable global transcription activator SNF2L1;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase SMARCA1;
DE   AltName: Full=Nucleosome-remodeling factor subunit SNF2L;
DE   AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1;
GN   Name=SMARCA1; Synonyms=SNF2L, SNF2L1;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:MGI.
DR   GO; GO:0007420; P:brain development; IMP:HGNC.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:HGNC.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:GOC.
DR   GO; GO:0030182; P:neuron differentiation; ISS:HGNC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:HGNC.
DR   GO; GO:2000177; P:regulation of neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IMP:HGNC.
//
ID   SMCA2_HUMAN             Reviewed;        1590 AA.
AC   P51531; B1ALG3; B1ALG4; D3DRH4; D3DRH5;
DE   RecName: Full=Probable global transcription activator SNF2L2;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase SMARCA2;
DE   AltName: Full=BRG1-associated factor 190B;
DE            Short=BAF190B;
DE   AltName: Full=Protein brahma homolog;
DE            Short=hBRM;
DE   AltName: Full=SNF2-alpha;
DE   AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2;
GN   Name=SMARCA2; Synonyms=BAF190B, BRM, SNF2A, SNF2L2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; TAS:BHF-UCL.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0035887; P:aortic smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
//
ID   SMCA5_HUMAN             Reviewed;        1052 AA.
AC   O60264;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5;
DE            Short=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5;
DE            EC=3.6.4.-;
DE   AltName: Full=Sucrose nonfermenting protein 2 homolog;
DE            Short=hSNF2H;
GN   Name=SMARCA5; Synonyms=SNF2H, WCRF135;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IMP:BHF-UCL.
DR   GO; GO:0034080; P:CENP-A containing nucleosome assembly at centromere; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; IEA:Ensembl.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
DR   GO; GO:0016584; P:nucleosome positioning; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   SMCE1_HUMAN             Reviewed;         411 AA.
AC   Q969G3; B3KMC1; B4DFR4; C0IMW4; C0IMW5; C0IMW7; H7C3F6; O43539;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1;
DE   AltName: Full=BRG1-associated factor 57;
DE            Short=BAF57;
GN   Name=SMARCE1; Synonyms=BAF57;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
//
ID   SMCA4_HUMAN             Reviewed;        1647 AA.
AC   P51532; B1A8Z4; B1A8Z5; B1A8Z6; B1A8Z7; E9PBR8; O95052; Q9HBD3;
DE   RecName: Full=Transcription activator BRG1;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase SMARCA4;
DE   AltName: Full=BRG1-associated factor 190A;
DE            Short=BAF190A;
DE   AltName: Full=Mitotic growth and transcription activator;
DE   AltName: Full=Protein BRG-1;
DE   AltName: Full=Protein brahma homolog 1;
DE   AltName: Full=SNF2-beta;
DE   AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;
GN   Name=SMARCA4; Synonyms=BAF190A, BRG1, SNF2B, SNF2L4;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IGI:BHF-UCL.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:BHF-UCL.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0030957; F:Tat protein binding; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0035887; P:aortic smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006200; P:ATP catabolic process; IGI:GOC.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0001832; P:blastocyst growth; IEA:Ensembl.
DR   GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0060318; P:definitive erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010424; P:DNA methylation on cytosine within a CG sequence; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0048562; P:embryonic organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0048730; P:epidermis morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007403; P:glial cell fate determination; IEA:Ensembl.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0043966; P:histone H3 acetylation; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0006346; P:methylation-dependent chromatin silencing; IEA:Ensembl.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; TAS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.
DR   GO; GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; TAS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0003407; P:neural retina development; IEP:BHF-UCL.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IMP:BHF-UCL.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   SMCO2_HUMAN             Reviewed;         343 AA.
AC   A6NFE2;
DE   RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 2;
GN   Name=SMCO2; Synonyms=C12orf70;
//
ID   SMCO1_HUMAN             Reviewed;         214 AA.
AC   Q147U7; B3KW20;
DE   RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 1;
DE   AltName: Full=Single-pass membrane protein with coiled-coil domains 1;
GN   Name=SMCO1; Synonyms=C3orf43;
//
ID   SMCO4_HUMAN             Reviewed;          59 AA.
AC   Q9NRQ5;
DE   RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 4;
DE   AltName: Full=Protein FN5;
GN   Name=SMCO4; Synonyms=C11orf75, FN5;
//
ID   SMCR5_HUMAN             Reviewed;         140 AA.
AC   Q8TEV8;
DE   RecName: Full=Smith-Magenis syndrome chromosomal region candidate gene 5 protein;
GN   Name=SMCR5;
//
ID   SMCO3_HUMAN             Reviewed;         225 AA.
AC   A2RU48; Q8NAI5;
DE   RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 3;
GN   Name=SMCO3; Synonyms=C12orf69;
//
ID   SMCR8_HUMAN             Reviewed;         937 AA.
AC   Q8TEV9; A5PKZ5; Q3ZCN0; Q6PJL3;
DE   RecName: Full=Smith-Magenis syndrome chromosomal region candidate gene 8 protein;
GN   Name=SMCR8;
//
ID   SMCR9_HUMAN             Reviewed;         180 AA.
AC   P0DM48;
DE   RecName: Full=Smith-Magenis syndrome chromosomal region candidate gene 9 protein;
GN   Name=SMCR9;
//
ID   SMD1_HUMAN              Reviewed;         119 AA.
AC   P62314; B5BTZ1; P13641;
DE   RecName: Full=Small nuclear ribonucleoprotein Sm D1;
DE            Short=Sm-D1;
DE   AltName: Full=Sm-D autoantigen;
DE   AltName: Full=snRNP core protein D1;
GN   Name=SNRPD1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000245; P:spliceosomal complex assembly; TAS:ProtInc.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   SMD2_HUMAN              Reviewed;         118 AA.
AC   P62316; A8K797; J3KPM5; P43330;
DE   RecName: Full=Small nuclear ribonucleoprotein Sm D2;
DE            Short=Sm-D2;
DE   AltName: Full=snRNP core protein D2;
GN   Name=SNRPD2; Synonyms=SNRPD1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000245; P:spliceosomal complex assembly; TAS:ProtInc.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   SMD3_HUMAN              Reviewed;         126 AA.
AC   P62318; B5BU13; P43331;
DE   RecName: Full=Small nuclear ribonucleoprotein Sm D3;
DE            Short=Sm-D3;
DE   AltName: Full=snRNP core protein D3;
GN   Name=SNRPD3;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0071208; F:histone pre-mRNA DCP binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SMDC1_HUMAN             Reviewed;         183 AA.
AC   Q9NPB0; Q9H0D8;
DE   RecName: Full=SAYSvFN domain-containing protein 1;
GN   Name=SAYSD1; Synonyms=C6orf64;
//
ID   SMEK3_HUMAN             Reviewed;         832 AA.
AC   Q6ZMV5; Q96M31;
DE   RecName: Full=Putative SMEK homolog 3;
GN   Name=SMEK3P;
//
ID   SMG1L_HUMAN             Reviewed;         159 AA.
AC   Q6P435;
DE   RecName: Full=Putative uncharacterized SMG1-like protein;
//
ID   SMG1_HUMAN              Reviewed;        3661 AA.
AC   Q96Q15; O43305; Q13284; Q8NFX2; Q96QV0; Q96RW3;
DE   RecName: Full=Serine/threonine-protein kinase SMG1;
DE            Short=SMG-1;
DE            Short=hSMG-1;
DE            EC=2.7.11.1;
DE   AltName: Full=61E3.4;
DE   AltName: Full=Lambda/iota protein kinase C-interacting protein;
DE            Short=Lambda-interacting protein;
GN   Name=SMG1; Synonyms=ATX, KIAA0421, LIP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   SMG5_HUMAN              Reviewed;        1016 AA.
AC   Q9UPR3; D3DVB7; Q5QJE7; Q659C7; Q8IXC0; Q8IY09; Q96IJ7;
DE   RecName: Full=Protein SMG5;
DE   AltName: Full=EST1-like protein B;
DE   AltName: Full=LPTS-RP1;
DE   AltName: Full=LPTS-interacting protein;
DE   AltName: Full=SMG-5 homolog;
DE            Short=hSMG-5;
GN   Name=SMG5; Synonyms=EST1B, KIAA1089;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:HGNC.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:HGNC.
DR   GO; GO:0035303; P:regulation of dephosphorylation; IMP:HGNC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   SMG7_HUMAN              Reviewed;        1137 AA.
AC   Q92540; B4DRB2; E9PCI0; E9PEH2; Q5T1Q0; Q6PIE0; Q7Z7H9; Q8IXC1;
AC   Q8IXC2;
DE   RecName: Full=Protein SMG7;
DE   AltName: Full=EST1-like protein C;
DE   AltName: Full=SMG-7 homolog;
DE            Short=hSMG-7;
GN   Name=SMG7; Synonyms=C1orf16, EST1C, KIAA0250;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:HGNC.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:HGNC.
DR   GO; GO:0035303; P:regulation of dephosphorylation; TAS:HGNC.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   SMG8_HUMAN              Reviewed;         991 AA.
AC   Q8ND04; Q8N5U5; Q8TDN0; Q9H5P5; Q9NVQ1;
DE   RecName: Full=Protein SMG8;
DE   AltName: Full=Amplified in breast cancer gene 2 protein;
DE   AltName: Full=Protein smg-8 homolog;
GN   Name=SMG8; Synonyms=ABC2, C17orf71;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   SMG9_HUMAN              Reviewed;         520 AA.
AC   Q9H0W8; O60429; Q9H9A9;
DE   RecName: Full=Protein SMG9;
DE   AltName: Full=Protein smg-9 homolog;
GN   Name=SMG9; Synonyms=C19orf61;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   SMHD1_HUMAN             Reviewed;        2005 AA.
AC   A6NHR9; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39;
DE   RecName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1;
DE   AltName: Full=SMC hinge domain-containing protein 1;
GN   Name=SMCHD1; Synonyms=KIAA0650;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0060821; P:inactivation of X chromosome by DNA methylation; IEA:Ensembl.
//
ID   SMI19_HUMAN             Reviewed;         107 AA.
AC   Q96E16; B2R4S6; D3DSY4;
DE   RecName: Full=Small integral membrane protein 19;
GN   Name=SMIM19; Synonyms=C8orf40;
//
ID   SMI20_HUMAN             Reviewed;         168 AA.
AC   Q8N5G0; C9JYT8; Q9BRT5;
DE   RecName: Full=Small integral membrane protein 20;
GN   Name=SMIM20; Synonyms=C4orf52;
//
ID   SMI21_HUMAN             Reviewed;         101 AA.
AC   Q3B7S5;
DE   RecName: Full=Small integral membrane protein 21;
GN   Name=SMIM21; Synonyms=C18orf62;
//
ID   SMIM1_HUMAN             Reviewed;          78 AA.
AC   B2RUZ4;
DE   RecName: Full=Small integral membrane protein 1;
DE   AltName: Full=Vel blood group antigen;
GN   Name=SMIM1;
//
ID   SMIM3_HUMAN             Reviewed;          60 AA.
AC   Q9BZL3; Q3MIG3; Q6ZUV4;
DE   RecName: Full=Small integral membrane protein 3;
DE   AltName: Full=NGF-induced differentiation clone 67 protein;
DE   AltName: Full=Small membrane protein NID67;
GN   Name=SMIM3; Synonyms=C5orf62, NID67;
//
ID   SMIM4_HUMAN             Reviewed;          70 AA.
AC   Q8WVI0;
DE   RecName: Full=Small integral membrane protein 4;
GN   Name=SMIM4; Synonyms=C3orf78;
//
ID   SMIM2_HUMAN             Reviewed;          85 AA.
AC   Q9BVW6; Q5SZS7;
DE   RecName: Full=Small integral membrane protein 2;
GN   Name=SMIM2; Synonyms=C13orf44;
//
ID   SMIM5_HUMAN             Reviewed;          77 AA.
AC   Q71RC9;
DE   RecName: Full=Small integral membrane protein 5;
GN   Name=SMIM5; Synonyms=C17orf109;
//
ID   SMIM7_HUMAN             Reviewed;          75 AA.
AC   Q9BQ49; A8MX44;
DE   RecName: Full=Small integral membrane protein 7;
DE   Flags: Precursor;
GN   Name=SMIM7; Synonyms=C19orf42;
//
ID   SMIM8_HUMAN             Reviewed;          97 AA.
AC   Q96KF7; B2R4V6; E1P505; Q5TEZ3; Q6NSD2; Q8IZ10;
DE   RecName: Full=Small integral membrane protein 8;
GN   Name=SMIM8; Synonyms=C6orf162; ORFNames=DC18;
//
ID   SMIM9_HUMAN             Reviewed;          99 AA.
AC   A6NGZ8;
DE   RecName: Full=Small integral membrane protein 9;
DE   Flags: Precursor;
GN   Name=SMIM9; Synonyms=CXorf68;
//
ID   SMIM6_HUMAN             Reviewed;          62 AA.
AC   P0DI80;
DE   RecName: Full=Small integral membrane protein 6;
GN   Name=SMIM6; Synonyms=C17orf110;
//
ID   SMKR1_HUMAN             Reviewed;          65 AA.
AC   H3BMG3;
DE   RecName: Full=Small lysine-rich protein 1;
GN   Name=SMKR1;
//
ID   SMLR1_HUMAN             Reviewed;         107 AA.
AC   H3BR10;
DE   RecName: Full=Small leucine-rich protein 1;
GN   Name=SMLR1;
//
ID   SMN_HUMAN               Reviewed;         294 AA.
AC   Q16637; A8K0V4; Q13119; Q549U5; Q96J51;
DE   RecName: Full=Survival motor neuron protein;
DE   AltName: Full=Component of gems 1;
DE   AltName: Full=Gemin-1;
GN   Name=SMN1; Synonyms=SMN, SMNT;
GN   and
GN   Name=SMN2; Synonyms=SMNC;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IMP:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
//
ID   SMOC1_HUMAN             Reviewed;         434 AA.
AC   Q9H4F8; A8K1S3; B2R7P5; Q96F78;
DE   RecName: Full=SPARC-related modular calcium-binding protein 1;
DE   AltName: Full=Secreted modular calcium-binding protein 1;
DE            Short=SMOC-1;
DE   Flags: Precursor;
GN   Name=SMOC1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
DR   GO; GO:0060173; P:limb development; IMP:UniProtKB.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SMOC2_HUMAN             Reviewed;         446 AA.
AC   Q9H3U7; B3KPS7; Q4G169; Q5TAT7; Q5TAT8; Q86VV9; Q96SF3; Q9H1L3;
AC   Q9H1L4; Q9H3U0; Q9H4F7; Q9HCV2;
DE   RecName: Full=SPARC-related modular calcium-binding protein 2;
DE   AltName: Full=Secreted modular calcium-binding protein 2;
DE            Short=SMOC-2;
DE   AltName: Full=Smooth muscle-associated protein 2;
DE            Short=SMAP-2;
DE   Flags: Precursor;
GN   Name=SMOC2; Synonyms=SMAP2; ORFNames=MSTP117;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SMOX_HUMAN              Reviewed;         555 AA.
AC   Q9NWM0; A2A2P5; A2A2P6; A8BE87; D3DVZ4; Q5TE26; Q5TE27; Q6UY28;
AC   Q8IX00; Q96LC3; Q96LC4; Q96QT3; Q9BW38; Q9H6H1; Q9NP51; Q9NPY1;
AC   Q9NPY2;
DE   RecName: Full=Spermine oxidase;
DE            EC=1.5.3.16;
DE   AltName: Full=Polyamine oxidase 1;
DE            Short=PAO-1;
DE            Short=PAOh1;
GN   Name=SMOX; Synonyms=C20orf16, SMO; ORFNames=UNQ3039/PRO9854;
DR   GO; GO:0052895; F:N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0052894; F:norspermine:oxygen oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046592; F:polyamine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0052901; F:spermine:oxygen oxidoreductase (spermidine-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0006596; P:polyamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0006598; P:polyamine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046208; P:spermine catabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   SMO_HUMAN               Reviewed;         787 AA.
AC   Q99835; A4D1K5;
DE   RecName: Full=Smoothened homolog;
DE            Short=SMO;
DE   AltName: Full=Protein Gx;
DE   Flags: Precursor;
GN   Name=SMO; Synonyms=SMOH;
DR   GuidetoPHARMACOLOGY; 239; -.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005113; F:patched binding; IPI:BHF-UCL.
DR   GO; GO:0030165; F:PDZ domain binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042813; F:Wnt-activated receptor activity; IBA:RefGenome.
DR   GO; GO:0017147; F:Wnt-protein binding; IBA:RefGenome.
DR   GO; GO:0021984; P:adenohypophysis development; IBA:RefGenome.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0048846; P:axon extension involved in axon guidance; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0010002; P:cardioblast differentiation; IBA:RefGenome.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0071397; P:cellular response to cholesterol; ISS:BHF-UCL.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; IBA:RefGenome.
DR   GO; GO:0021696; P:cerebellar cortex morphogenesis; IBA:RefGenome.
DR   GO; GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IBA:RefGenome.
DR   GO; GO:0060248; P:detection of cell density by contact stimulus involved in contact inhibition; IMP:BHF-UCL.
DR   GO; GO:0003140; P:determination of left/right asymmetry in lateral mesoderm; ISS:BHF-UCL.
DR   GO; GO:0007368; P:determination of left/right symmetry; IBA:RefGenome.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IBA:RefGenome.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IBA:RefGenome.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IBA:RefGenome.
DR   GO; GO:0048702; P:embryonic neurocranium morphogenesis; IBA:RefGenome.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IBA:RefGenome.
DR   GO; GO:0060684; P:epithelial-mesenchymal cell signaling; IEA:Ensembl.
DR   GO; GO:0031017; P:exocrine pancreas development; IBA:RefGenome.
DR   GO; GO:0021561; P:facial nerve development; IBA:RefGenome.
DR   GO; GO:0021508; P:floor plate formation; IBA:RefGenome.
DR   GO; GO:0048853; P:forebrain morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0008406; P:gonad development; IBA:RefGenome.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; IBA:RefGenome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0072285; P:mesenchymal to epithelial transition involved in metanephric renal vesicle formation; ISS:UniProtKB.
DR   GO; GO:0007494; P:midgut development; ISS:BHF-UCL.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0042693; P:muscle cell fate commitment; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:0043392; P:negative regulation of DNA binding; ISS:UniProtKB.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0051799; P:negative regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IBA:RefGenome.
DR   GO; GO:0048663; P:neuron fate commitment; IBA:RefGenome.
DR   GO; GO:0031102; P:neuron projection regeneration; IBA:RefGenome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IBA:RefGenome.
DR   GO; GO:0001649; P:osteoblast differentiation; IBA:RefGenome.
DR   GO; GO:0032474; P:otolith morphogenesis; IBA:RefGenome.
DR   GO; GO:0061113; P:pancreas morphogenesis; IEA:Ensembl.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IBA:RefGenome.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IBA:RefGenome.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:2000826; P:regulation of heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0072001; P:renal system development; IEP:UniProtKB.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; IBA:RefGenome.
DR   GO; GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB.
DR   GO; GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IBA:RefGenome.
DR   GO; GO:0021910; P:smoothened signaling pathway involved in ventral spinal cord patterning; IBA:RefGenome.
DR   GO; GO:0061053; P:somite development; ISS:BHF-UCL.
DR   GO; GO:0007283; P:spermatogenesis; IBA:RefGenome.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0003323; P:type B pancreatic cell development; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IBA:RefGenome.
DR   GO; GO:0007371; P:ventral midline determination; ISS:BHF-UCL.
//
ID   SMPX_HUMAN              Reviewed;          88 AA.
AC   Q9UHP9; B1AWX2;
DE   RecName: Full=Small muscular protein;
DE   AltName: Full=Stretch-responsive skeletal muscle protein;
GN   Name=SMPX; Synonyms=SRMX;
DR   GO; GO:0006941; P:striated muscle contraction; TAS:ProtInc.
//
ID   SMR3B_HUMAN             Reviewed;          79 AA.
AC   P02814; B7ZMG7; Q9UBN0; Q9UCT0;
DE   RecName: Full=Submaxillary gland androgen-regulated protein 3B;
DE   AltName: Full=Proline-rich peptide P-B;
DE   AltName: Full=Proline-rich protein 3;
DE   Contains:
DE     RecName: Full=Peptide P-A;
DE   Contains:
DE     RecName: Full=Peptide D1A;
DE   Flags: Precursor;
GN   Name=SMR3B; Synonyms=PBII, PRL3, PROL3;
//
ID   SMR3A_HUMAN             Reviewed;         134 AA.
AC   Q99954;
DE   RecName: Full=Submaxillary gland androgen-regulated protein 3A;
DE   AltName: Full=Proline-rich protein 5;
DE   AltName: Full=Proline-rich protein PBI;
DE   Flags: Precursor;
GN   Name=SMR3A; Synonyms=PBI, PROL5;
//
ID   SMRC1_HUMAN             Reviewed;        1105 AA.
AC   Q92922; Q17RS0; Q6P172; Q8IWH2;
DE   RecName: Full=SWI/SNF complex subunit SMARCC1;
DE   AltName: Full=BRG1-associated factor 155;
DE            Short=BAF155;
DE   AltName: Full=SWI/SNF complex 155 kDa subunit;
DE   AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1;
GN   Name=SMARCC1; Synonyms=BAF155;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMRC2_HUMAN             Reviewed;        1214 AA.
AC   Q8TAQ2; F8VTJ5; Q59GV3; Q92923; Q96E12; Q96GY4;
DE   RecName: Full=SWI/SNF complex subunit SMARCC2;
DE   AltName: Full=BRG1-associated factor 170;
DE            Short=BAF170;
DE   AltName: Full=SWI/SNF complex 170 kDa subunit;
DE   AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2;
GN   Name=SMARCC2; Synonyms=BAF170;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMRCD_HUMAN             Reviewed;        1026 AA.
AC   Q9H4L7; B7Z799; Q05D56; Q96SX1; Q9H017; Q9H860; Q9NPU9; Q9ULU7;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase 1;
DE            Short=hHEL1;
GN   Name=SMARCAD1; Synonyms=KIAA1122;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IMP:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; NAS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0051304; P:chromosome separation; IMP:UniProtKB.
DR   GO; GO:0000729; P:DNA double-strand break processing; IMP:UniProtKB.
DR   GO; GO:0070932; P:histone H3 deacetylation; IMP:UniProtKB.
DR   GO; GO:0070933; P:histone H4 deacetylation; IMP:UniProtKB.
DR   GO; GO:0009117; P:nucleotide metabolic process; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; NAS:UniProtKB.
DR   GO; GO:0000018; P:regulation of DNA recombination; IEP:UniProtKB.
//
ID   SMRD2_HUMAN             Reviewed;         531 AA.
AC   Q92925; A5PLL5; A6NNQ7; B4DV56; B4E1R6; Q7L2I6; Q9UHZ1;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2;
DE   AltName: Full=60 kDa BRG-1/Brm-associated factor subunit B;
DE   AltName: Full=BRG1-associated factor 60B;
DE            Short=BAF60B;
GN   Name=SMARCD2; Synonyms=BAF60B; ORFNames=PRO2451;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMRP1_HUMAN             Reviewed;         262 AA.
AC   Q8NCR6; Q5T598; Q5T599; Q5T5A0; Q8N9G4; Q96KD1; Q96LN1;
DE   RecName: Full=Spermatid-specific manchette-related protein 1;
DE   AltName: Full=Ciliated bronchial epithelial protein 1;
DE   AltName: Full=Testis development protein NYD-SP22;
GN   Name=SMRP1; Synonyms=C9orf24, CBE1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043623; P:cellular protein complex assembly; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SMRD3_HUMAN             Reviewed;         483 AA.
AC   Q6STE5; D3DX10; Q2YD86; Q75MJ2; Q75MR8; Q92926; Q9BUH1;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3;
DE   AltName: Full=60 kDa BRG-1/Brm-associated factor subunit C;
DE   AltName: Full=BRG1-associated factor 60C;
DE            Short=BAF60C;
GN   Name=SMARCD3; Synonyms=BAF60C;
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:BHF-UCL.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:BHF-UCL.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003219; P:cardiac right ventricle formation; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0003407; P:neural retina development; IEP:BHF-UCL.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0003139; P:secondary heart field specification; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   SMRD1_HUMAN             Reviewed;         515 AA.
AC   Q96GM5; A6NN27; Q92924; Q9Y635;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1;
DE   AltName: Full=60 kDa BRG-1/Brm-associated factor subunit A;
DE   AltName: Full=BRG1-associated factor 60A;
DE            Short=BAF60A;
DE   AltName: Full=SWI/SNF complex 60 kDa subunit;
GN   Name=SMARCD1; Synonyms=BAF60A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032947; F:protein complex scaffold; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:BHF-UCL.
DR   GO; GO:0006338; P:chromatin remodeling; IMP:UniProtKB.
DR   GO; GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
//
ID   SMS1_HUMAN              Reviewed;         419 AA.
AC   Q86VZ5; Q68U43; Q6EKK0; Q75SP1;
DE   RecName: Full=Phosphatidylcholine:ceramide cholinephosphotransferase 1;
DE            EC=2.7.8.27;
DE   AltName: Full=Medulla oblongata-derived protein;
DE            Short=Protein Mob;
DE   AltName: Full=Sphingomyelin synthase 1;
DE   AltName: Full=Transmembrane protein 23;
GN   Name=SGMS1; Synonyms=MOB, SMS1, TMEM23;
DR   GO; GO:0047493; F:ceramide cholinephosphotransferase activity; IDA:UniProtKB.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0033188; F:sphingomyelin synthase activity; IMP:HGNC.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0016049; P:cell growth; IDA:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006686; P:sphingomyelin biosynthetic process; IDA:UniProtKB.
//
ID   SMS2_HUMAN              Reviewed;         365 AA.
AC   Q8NHU3; A8K2S9; B2RA61;
DE   RecName: Full=Phosphatidylcholine:ceramide cholinephosphotransferase 2;
DE            EC=2.7.8.27;
DE   AltName: Full=Sphingomyelin synthase 2;
GN   Name=SGMS2; Synonyms=SMS2;
DR   GO; GO:0047493; F:ceramide cholinephosphotransferase activity; IDA:UniProtKB.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0033188; F:sphingomyelin synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006686; P:sphingomyelin biosynthetic process; IDA:UniProtKB.
//
ID   SMS_HUMAN               Reviewed;         116 AA.
AC   P61278; B2R5G3; P01166;
DE   RecName: Full=Somatostatin;
DE   AltName: Full=Growth hormone release-inhibiting factor;
DE   Contains:
DE     RecName: Full=Somatostatin-28;
DE   Contains:
DE     RecName: Full=Somatostatin-14;
DE   Flags: Precursor;
GN   Name=SST;
DR   GO; GO:0005179; F:hormone activity; TAS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0007586; P:digestion; TAS:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0008628; P:hormone-mediated apoptotic signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006972; P:hyperosmotic response; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:UniProtKB.
DR   GO; GO:0048545; P:response to steroid hormone; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:UniProtKB.
//
ID   SMTL1_HUMAN             Reviewed;         457 AA.
AC   A8MU46;
DE   RecName: Full=Smoothelin-like protein 1;
GN   Name=SMTNL1;
DR   GO; GO:0045908; P:negative regulation of vasodilation; ISS:UniProtKB.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; ISS:UniProtKB.
//
ID   SMTL2_HUMAN             Reviewed;         461 AA.
AC   Q2TAL5; Q6ZVK6;
DE   RecName: Full=Smoothelin-like protein 2;
GN   Name=SMTNL2;
//
ID   SMTN_HUMAN              Reviewed;         917 AA.
AC   P53814; O00569; O95769; O95937; Q8N4H8; Q8WWW1; Q8WWW2; Q9P1S8;
AC   Q9UIT1; Q9UIT2;
DE   RecName: Full=Smoothelin;
GN   Name=SMTN; Synonyms=SMSMO;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0006939; P:smooth muscle contraction; TAS:ProtInc.
//
ID   SMU1_HUMAN              Reviewed;         513 AA.
AC   Q2TAY7; Q9BU59; Q9HA96; Q9NVD1;
DE   RecName: Full=WD40 repeat-containing protein SMU1;
DE   AltName: Full=Smu-1 suppressor of mec-8 and unc-52 protein homolog;
DE   Contains:
DE     RecName: Full=WD40 repeat-containing protein SMU1, N-terminally processed;
GN   Name=SMU1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SMUF1_HUMAN             Reviewed;         757 AA.
AC   Q9HCE7; A4D279; B7ZMB6; B9EGV3; O75853; Q547Q3; Q9UJT8;
DE   RecName: Full=E3 ubiquitin-protein ligase SMURF1;
DE            Short=hSMURF1;
DE            EC=6.3.2.-;
DE   AltName: Full=SMAD ubiquitination regulatory factor 1;
DE   AltName: Full=SMAD-specific E3 ubiquitin-protein ligase 1;
GN   Name=SMURF1; Synonyms=KIAA1625;
DR   GO; GO:0048185; F:activin binding; NAS:BHF-UCL.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:0007398; P:ectoderm development; TAS:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0032801; P:receptor catabolic process; IDA:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
//
ID   SMUF2_HUMAN             Reviewed;         748 AA.
AC   Q9HAU4; Q52LL1; Q9H260;
DE   RecName: Full=E3 ubiquitin-protein ligase SMURF2;
DE            Short=hSMURF2;
DE            EC=6.3.2.-;
DE   AltName: Full=SMAD ubiquitination regulatory factor 2;
DE   AltName: Full=SMAD-specific E3 ubiquitin-protein ligase 2;
GN   Name=SMURF2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
//
ID   SMUG1_HUMAN             Reviewed;         270 AA.
AC   Q53HV7; A8K2K9; O95862; Q0D2M0; Q8NB71; Q9BWC8;
DE   RecName: Full=Single-strand selective monofunctional uracil DNA glycosylase;
DE            EC=3.2.2.-;
GN   Name=SMUG1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019104; F:DNA N-glycosylase activity; IDA:HGNC.
DR   GO; GO:0000703; F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017065; F:single-strand selective uracil DNA N-glycosylase activity; IDA:HGNC.
DR   GO; GO:0004844; F:uracil DNA N-glycosylase activity; IDA:HGNC.
DR   GO; GO:0006284; P:base-excision repair; IDA:HGNC.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0045008; P:depyrimidination; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
//
ID   SMYD1_HUMAN             Reviewed;         490 AA.
AC   Q8NB12; A0AV30; A6NE13;
DE   RecName: Full=Histone-lysine N-methyltransferase SMYD1;
DE            EC=2.1.1.43;
DE   AltName: Full=SET and MYND domain-containing protein 1;
GN   Name=SMYD1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; IDA:BHF-UCL.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMYD2_HUMAN             Reviewed;         433 AA.
AC   Q9NRG4; B2R9P9; Q4V765; Q5VSH9; Q96AI4;
DE   RecName: Full=N-lysine methyltransferase SMYD2;
DE            EC=2.1.1.-;
DE   AltName: Full=HSKM-B;
DE   AltName: Full=Histone methyltransferase SMYD2;
DE            EC=2.1.1.43;
DE   AltName: Full=Lysine N-methyltransferase 3C;
DE   AltName: Full=SET and MYND domain-containing protein 2;
GN   Name=SMYD2; Synonyms=KMT3C;
DR   GuidetoPHARMACOLOGY; 2714; -.
DR   GO; GO:0046975; F:histone methyltransferase activity (H3-K36 specific); ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0000993; F:RNA polymerase II core binding; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.
DR   GO; GO:0018026; P:peptidyl-lysine monomethylation; IDA:UniProtKB.
DR   GO; GO:0043516; P:regulation of DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SMYD3_HUMAN             Reviewed;         428 AA.
AC   Q9H7B4; A8K0P0; B1AN38; Q86TL8; Q8N5Z6; Q96AI5;
DE   RecName: Full=Histone-lysine N-methyltransferase SMYD3;
DE            EC=2.1.1.43;
DE   AltName: Full=SET and MYND domain-containing protein 3;
DE   AltName: Full=Zinc finger MYND domain-containing protein 1;
GN   Name=SMYD3; Synonyms=ZMYND1, ZNFN3A1;
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   SMYD4_HUMAN             Reviewed;         804 AA.
AC   Q8IYR2; Q8N1P2; Q8NAT0; Q96LV4; Q96PV2;
DE   RecName: Full=SET and MYND domain-containing protein 4;
DE            EC=2.1.1.-;
GN   Name=SMYD4; Synonyms=KIAA1936;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   SMYD5_HUMAN             Reviewed;         418 AA.
AC   Q6GMV2; D6W5H3; Q13558;
DE   RecName: Full=SET and MYND domain-containing protein 5;
DE            EC=2.1.1.-;
DE   AltName: Full=Protein NN8-4AG;
DE   AltName: Full=Retinoic acid-induced protein 15;
GN   Name=SMYD5; Synonyms=RAI15;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   SN12L_HUMAN             Reviewed;         588 AA.
AC   Q6IEE8; F5H6G3;
DE   RecName: Full=Schlafen family member 12-like;
GN   Name=SLFN12L; Synonyms=SLFN5;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
//
ID   SNAA_HUMAN              Reviewed;         295 AA.
AC   P54920; A8K879; Q96IK3; Q9BVJ3;
DE   RecName: Full=Alpha-soluble NSF attachment protein;
DE            Short=SNAP-alpha;
DE   AltName: Full=N-ethylmaleimide-sensitive factor attachment protein alpha;
GN   Name=NAPA; Synonyms=SNAPA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045176; P:apical protein localization; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:Ensembl.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0010807; P:regulation of synaptic vesicle priming; IEA:Ensembl.
DR   GO; GO:0035494; P:SNARE complex disassembly; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
//
ID   SNAB_HUMAN              Reviewed;         298 AA.
AC   Q9H115; Q4G187; Q5JXF9; Q8N3C4;
DE   RecName: Full=Beta-soluble NSF attachment protein;
DE            Short=SNAP-beta;
DE   AltName: Full=N-ethylmaleimide-sensitive factor attachment protein beta;
GN   Name=NAPB; Synonyms=SNAPB;
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0010807; P:regulation of synaptic vesicle priming; IEA:Ensembl.
DR   GO; GO:0035494; P:SNARE complex disassembly; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
//
ID   SNAG_HUMAN              Reviewed;         312 AA.
AC   Q99747; Q9BUV1;
DE   RecName: Full=Gamma-soluble NSF attachment protein;
DE            Short=SNAP-gamma;
DE   AltName: Full=N-ethylmaleimide-sensitive factor attachment protein gamma;
GN   Name=NAPG; Synonyms=SNAPG;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0006461; P:protein complex assembly; NAS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; NAS:UniProtKB.
//
ID   SNAI1_HUMAN             Reviewed;         264 AA.
AC   O95863; B2R842; Q9P113; Q9UBP7; Q9UHH7;
DE   RecName: Full=Zinc finger protein SNAI1;
DE   AltName: Full=Protein snail homolog 1;
DE            Short=Protein sna;
GN   Name=SNAI1; Synonyms=SNAH;
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0060972; P:left/right pattern formation; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; ISS:UniProtKB.
DR   GO; GO:0060806; P:negative regulation of cell differentiation involved in embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0010957; P:negative regulation of vitamin D biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; ISS:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:UniProtKB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IMP:BHF-UCL.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
//
ID   SNAI2_HUMAN             Reviewed;         268 AA.
AC   O43623; B2R6P6; Q53FC1;
DE   RecName: Full=Zinc finger protein SNAI2;
DE   AltName: Full=Neural crest transcription factor Slug;
DE   AltName: Full=Protein snail homolog 2;
GN   Name=SNAI2; Synonyms=SLUG, SLUGH;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060536; P:cartilage morphogenesis; IEA:Ensembl.
DR   GO; GO:0003273; P:cell migration involved in endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0035921; P:desmosome disassembly; IMP:BHF-UCL.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0060429; P:epithelium development; ISS:BHF-UCL.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0006933; P:negative regulation of cell adhesion involved in substrate-bound cell migration; IEA:Ensembl.
DR   GO; GO:0033629; P:negative regulation of cell adhesion mediated by integrin; IC:BHF-UCL.
DR   GO; GO:1900387; P:negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; ISS:BHF-UCL.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IDA:BHF-UCL.
DR   GO; GO:2000647; P:negative regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0010957; P:negative regulation of vitamin D biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0070563; P:negative regulation of vitamin D receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0014032; P:neural crest cell development; IMP:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; IEP:UniProtKB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; IMP:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0060693; P:regulation of branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0032642; P:regulation of chemokine production; IMP:BHF-UCL.
DR   GO; GO:0045667; P:regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:2000810; P:regulation of tight junction assembly; IMP:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.
DR   GO; GO:0050872; P:white fat cell differentiation; IEA:Ensembl.
//
ID   SNAI3_HUMAN             Reviewed;         292 AA.
AC   Q3KNW1; Q86SU5;
DE   RecName: Full=Zinc finger protein SNAI3;
DE   AltName: Full=Protein snail homolog 3;
DE   AltName: Full=Zinc finger protein 293;
GN   Name=SNAI3; Synonyms=ZNF293;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SNAPN_HUMAN             Reviewed;         136 AA.
AC   O95295; D3DV56; Q5SXU8;
DE   RecName: Full=SNARE-associated protein Snapin;
DE   AltName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 7;
DE            Short=BLOC-1 subunit 7;
DE   AltName: Full=Synaptosomal-associated protein 25-binding protein;
DE            Short=SNAP-associated protein;
GN   Name=SNAPIN; Synonyms=BLOC1S7, SNAP25BP, SNAPAP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000149; F:SNARE binding; IDA:MGI.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:UniProtKB.
DR   GO; GO:0048490; P:anterograde synaptic vesicle transport; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0032438; P:melanosome organization; NAS:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; ISS:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:ProtInc.
DR   GO; GO:1902824; P:positive regulation of late endosome to lysosome transport; TAS:ParkinsonsUK-UCL.
DR   GO; GO:0043393; P:regulation of protein binding; IMP:ParkinsonsUK-UCL.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IDA:MGI.
DR   GO; GO:0031629; P:synaptic vesicle fusion to presynaptic membrane; IEA:Ensembl.
DR   GO; GO:0016188; P:synaptic vesicle maturation; IEA:Ensembl.
DR   GO; GO:0048489; P:synaptic vesicle transport; IMP:UniProtKB.
DR   GO; GO:0072553; P:terminal button organization; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SNAT_HUMAN              Reviewed;         207 AA.
AC   Q16613; A0AVF2; J3KMZ5; Q562F4;
DE   RecName: Full=Serotonin N-acetyltransferase;
DE            Short=Serotonin acetylase;
DE            EC=2.3.1.87;
DE   AltName: Full=Aralkylamine N-acetyltransferase;
DE            Short=AA-NAT;
GN   Name=AANAT; Synonyms=SNAT;
DR   GO; GO:0004059; F:aralkylamine N-acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071320; P:cellular response to cAMP; IDA:UniProtKB.
DR   GO; GO:0007623; P:circadian rhythm; IMP:UniProtKB.
DR   GO; GO:0046219; P:indolalkylamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0030187; P:melatonin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SNCAP_HUMAN             Reviewed;         919 AA.
AC   Q9Y6H5; D3DSZ1; Q05BS1; Q1PSC2; Q49AC6; Q504U9; Q6L984; Q6L985;
AC   Q6L986; Q9HC59;
DE   RecName: Full=Synphilin-1;
DE            Short=Sph1;
DE   AltName: Full=Alpha-synuclein-interacting protein;
GN   Name=SNCAIP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0042417; P:dopamine metabolic process; IDA:MGI.
DR   GO; GO:0090083; P:regulation of inclusion body assembly; IDA:BHF-UCL.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IDA:MGI.
//
ID   SND1_HUMAN              Reviewed;         910 AA.
AC   Q7KZF4; Q13122; Q96AG0;
DE   RecName: Full=Staphylococcal nuclease domain-containing protein 1;
DE   AltName: Full=100 kDa coactivator;
DE   AltName: Full=EBNA2 coactivator p100;
DE   AltName: Full=Tudor domain-containing protein 11;
DE   AltName: Full=p100 co-activator;
GN   Name=SND1; Synonyms=TDRD11;
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SNED1_HUMAN             Reviewed;        1413 AA.
AC   Q8TER0; B5MDC3; B7WNK6; B7WPM0; Q336F4; Q336F5; Q8N369; Q8TEP7;
DE   RecName: Full=Sushi, nidogen and EGF-like domain-containing protein 1;
DE   AltName: Full=Insulin-responsive sequence DNA-binding protein 1;
DE            Short=IRE-BP1;
DE   Flags: Precursor;
GN   Name=SNED1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
//
ID   SNF5_HUMAN              Reviewed;         385 AA.
AC   Q12824; O75784; O95474; Q17S11; Q38GA1; Q76N08; Q9UBH2;
DE   RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;
DE   AltName: Full=BRG1-associated factor 47;
DE            Short=BAF47;
DE   AltName: Full=Integrase interactor 1 protein;
DE   AltName: Full=SNF5 homolog;
DE            Short=hSNF5;
GN   Name=SMARCB1; Synonyms=BAF47, INI1, SNF5L1;
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030957; F:Tat protein binding; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IMP:BHF-UCL.
DR   GO; GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProt.
DR   GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.
DR   GO; GO:0015074; P:DNA integration; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; IBA:RefGenome.
DR   GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:RefGenome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IBA:RefGenome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IMP:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:BHF-UCL.
DR   GO; GO:0039692; P:single stranded viral RNA replication via double stranded DNA intermediate; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SNF8_HUMAN              Reviewed;         258 AA.
AC   Q96H20; Q8IXY3; Q9UN50;
DE   RecName: Full=Vacuolar-sorting protein SNF8;
DE   AltName: Full=ELL-associated protein of 30 kDa;
DE   AltName: Full=ESCRT-II complex subunit VPS22;
DE            Short=hVps22;
GN   Name=SNF8; Synonyms=EAP30;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IDA:MGI.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SNG1_HUMAN              Reviewed;         233 AA.
AC   O43759; A6NP69; A8K0E2; O43757; O43758; Q53Y02; Q96J56; Q9UGZ4;
DE   RecName: Full=Synaptogyrin-1;
GN   Name=SYNGR1;
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; ISS:UniProtKB.
//
ID   SNG2L_HUMAN             Reviewed;         223 AA.
AC   A8MWL6;
DE   RecName: Full=Putative synaptogyrin-2 like protein;
//
ID   SNG2_HUMAN              Reviewed;         224 AA.
AC   O43760; O43762; Q658S7;
DE   RecName: Full=Synaptogyrin-2;
DE   AltName: Full=Cellugyrin;
GN   Name=SYNGR2; ORFNames=UNQ352/PRO615;
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
//
ID   SNG3_HUMAN              Reviewed;         229 AA.
AC   O43761; B2R9S0;
DE   RecName: Full=Synaptogyrin-3;
GN   Name=SYNGR3;
DR   GO; GO:0032411; P:positive regulation of transporter activity; ISS:UniProtKB.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   SNH12_HUMAN             Reviewed;          62 AA.
AC   Q9BXW3;
DE   RecName: Full=Putative uncharacterized protein SNHG12;
DE   AltName: Full=Transformation-related gene 11 protein;
DE            Short=TRG-11;
GN   Name=SNHG12; Synonyms=C1orf79; ORFNames=PNAS-123, TRG11;
//
ID   SNIP1_HUMAN             Reviewed;         396 AA.
AC   Q8TAD8; Q96SP9; Q9H9T7;
DE   RecName: Full=Smad nuclear-interacting protein 1;
DE   AltName: Full=FHA domain-containing protein SNIP1;
GN   Name=SNIP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0035196; P:production of miRNAs involved in gene silencing by miRNA; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   SNG4_HUMAN              Reviewed;         234 AA.
AC   O95473; Q3KP58;
DE   RecName: Full=Synaptogyrin-4;
GN   Name=SYNGR4;
//
ID   SNIT1_HUMAN             Reviewed;         110 AA.
AC   Q9HBX3; B3KNA6; O95358;
DE   RecName: Full=Uncharacterized protein encoded by SND1-IT1;
DE   AltName: Full=Brain and nasopharyngeal carcinoma susceptibility protein NSG-x;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 8 protein;
DE   AltName: Full=SND1 intronic transcript 1;
GN   Name=SND1-IT1; Synonyms=C7orf54, NAG8;
//
ID   SNN_HUMAN               Reviewed;          88 AA.
AC   O75324; D3DUG4; Q6FGI0;
DE   RecName: Full=Stannin;
DE   AltName: Full=AG8_1;
GN   Name=SNN;
DR   GO; GO:0009628; P:response to abiotic stimulus; TAS:ProtInc.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   SNP23_HUMAN             Reviewed;         211 AA.
AC   O00161; O00162; Q13602; Q6IAE3;
DE   RecName: Full=Synaptosomal-associated protein 23;
DE            Short=SNAP-23;
DE   AltName: Full=Vesicle-membrane fusion protein SNAP-23;
GN   Name=SNAP23;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006903; P:vesicle targeting; TAS:ProtInc.
//
ID   SNP25_HUMAN             Reviewed;         206 AA.
AC   P60880; B2RAU4; D3DW16; D3DW17; P13795; P36974; P70557; P70558;
AC   Q53EM2; Q5U0B5; Q8IXK3; Q96FM2; Q9BR45;
DE   RecName: Full=Synaptosomal-associated protein 25;
DE            Short=SNAP-25;
DE   AltName: Full=Super protein;
DE            Short=SUP;
DE   AltName: Full=Synaptosomal-associated 25 kDa protein;
GN   Name=SNAP25; Synonyms=SNAP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0001504; P:neurotransmitter uptake; NAS:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; NAS:UniProtKB.
DR   GO; GO:0016081; P:synaptic vesicle docking involved in exocytosis; NAS:UniProtKB.
//
ID   SNP29_HUMAN             Reviewed;         258 AA.
AC   O95721;
DE   RecName: Full=Synaptosomal-associated protein 29;
DE            Short=SNAP-29;
DE   AltName: Full=Soluble 29 kDa NSF attachment protein;
DE   AltName: Full=Vesicle-membrane fusion protein SNAP-29;
GN   Name=SNAP29;
DR   GO; GO:0005484; F:SNAP receptor activity; TAS:ProtInc.
DR   GO; GO:0000046; P:autophagic vacuole fusion; IMP:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006903; P:vesicle targeting; TAS:ProtInc.
//
ID   SNP47_HUMAN             Reviewed;         464 AA.
AC   Q5SQN1; B6EDE0; Q5HYB5; Q5TBZ3; Q8N558; Q8TB31; Q8TCW8; Q8WV46;
AC   Q96CQ3; Q96FE1; Q96I66; Q96NU3; Q9BT10; Q9BVB2;
DE   RecName: Full=Synaptosomal-associated protein 47;
DE            Short=SNAP-47;
DE   AltName: Full=Epididymis luminal protein 170;
DE   AltName: Full=Synaptosomal-associated 47 kDa protein;
GN   Name=SNAP47; Synonyms=C1orf142, HEL170, SVAP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   SNPC1_HUMAN             Reviewed;         368 AA.
AC   Q16533;
DE   RecName: Full=snRNA-activating protein complex subunit 1;
DE            Short=SNAPc subunit 1;
DE   AltName: Full=Proximal sequence element-binding transcription factor subunit gamma;
DE            Short=PSE-binding factor subunit gamma;
DE            Short=PTF subunit gamma;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 1;
DE   AltName: Full=snRNA-activating protein complex 43 kDa subunit;
DE            Short=SNAPc 43 kDa subunit;
GN   Name=SNAPC1; Synonyms=SNAP43;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   SNPC2_HUMAN             Reviewed;         334 AA.
AC   Q13487; B2RBZ6; D6W663; Q13486;
DE   RecName: Full=snRNA-activating protein complex subunit 2;
DE            Short=SNAPc subunit 2;
DE   AltName: Full=Proximal sequence element-binding transcription factor subunit delta;
DE            Short=PSE-binding factor subunit delta;
DE            Short=PTF subunit delta;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 2;
DE   AltName: Full=snRNA-activating protein complex 45 kDa subunit;
DE            Short=SNAPc 45 kDa subunit;
GN   Name=SNAPC2; Synonyms=SNAP45;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0009301; P:snRNA transcription; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   SNPC3_HUMAN             Reviewed;         411 AA.
AC   Q92966; D3DRI8; Q2VPI6; Q5T285;
DE   RecName: Full=snRNA-activating protein complex subunit 3;
DE            Short=SNAPc subunit 3;
DE   AltName: Full=Proximal sequence element-binding transcription factor subunit beta;
DE            Short=PSE-binding factor subunit beta;
DE            Short=PTF subunit beta;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 3;
DE   AltName: Full=snRNA-activating protein complex 50 kDa subunit;
DE            Short=SNAPc 50 kDa subunit;
GN   Name=SNAPC3; Synonyms=SNAP50;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009301; P:snRNA transcription; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   SNPC4_HUMAN             Reviewed;        1469 AA.
AC   Q5SXM2; Q9Y6P7;
DE   RecName: Full=snRNA-activating protein complex subunit 4;
DE            Short=SNAPc subunit 4;
DE   AltName: Full=Proximal sequence element-binding transcription factor subunit alpha;
DE            Short=PSE-binding factor subunit alpha;
DE            Short=PTF subunit alpha;
DE   AltName: Full=snRNA-activating protein complex 190 kDa subunit;
DE            Short=SNAPc 190 kDa subunit;
GN   Name=SNAPC4; Synonyms=SNAP190;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0009301; P:snRNA transcription; TAS:ProtInc.
DR   GO; GO:0042795; P:snRNA transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042796; P:snRNA transcription from RNA polymerase III promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   SNPC5_HUMAN             Reviewed;          98 AA.
AC   O75971; A8K7N6; Q96CF3;
DE   RecName: Full=snRNA-activating protein complex subunit 5;
DE            Short=SNAPc subunit 5;
DE   AltName: Full=Small nuclear RNA-activating complex polypeptide 5;
DE   AltName: Full=snRNA-activating protein complex 19 kDa subunit;
DE            Short=SNAPc 19 kDa subunit;
GN   Name=SNAPC5; Synonyms=SNAP19;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006384; P:transcription initiation from RNA polymerase III promoter; TAS:ProtInc.
//
ID   SNPH_HUMAN              Reviewed;         494 AA.
AC   O15079; Q8IYI3;
DE   RecName: Full=Syntaphilin;
GN   Name=SNPH; Synonyms=KIAA0374;
DR   GO; GO:0017075; F:syntaxin-1 binding; NAS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; NAS:UniProtKB.
DR   GO; GO:0016081; P:synaptic vesicle docking involved in exocytosis; NAS:UniProtKB.
//
ID   SNR25_HUMAN             Reviewed;         132 AA.
AC   Q9BV90; Q1W6H3; Q6IEF8; Q9H5W4;
DE   RecName: Full=U11/U12 small nuclear ribonucleoprotein 25 kDa protein;
DE            Short=U11/U12 snRNP 25 kDa protein;
DE            Short=U11/U12-25K;
DE   AltName: Full=Minus-99 protein;
GN   Name=SNRNP25; Synonyms=C16orf33;
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   SNR27_HUMAN             Reviewed;         155 AA.
AC   Q8WVK2; Q15410;
DE   RecName: Full=U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein;
DE            Short=U4/U6.U5 snRNP 27 kDa protein;
DE            Short=U4/U6.U5-27K;
DE   AltName: Full=Nucleic acid-binding protein RY-1;
DE   AltName: Full=U4/U6.U5 tri-snRNP-associated 27 kDa protein;
DE            Short=27K;
DE   AltName: Full=U4/U6.U5 tri-snRNP-associated protein 3;
GN   Name=SNRNP27;
DR   GO; GO:0003676; F:nucleic acid binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SNR40_HUMAN             Reviewed;         357 AA.
AC   Q96DI7; O75938; O95320;
DE   RecName: Full=U5 small nuclear ribonucleoprotein 40 kDa protein;
DE            Short=U5 snRNP 40 kDa protein;
DE            Short=U5-40K;
DE   AltName: Full=38 kDa-splicing factor;
DE   AltName: Full=Prp8-binding protein;
DE            Short=hPRP8BP;
DE   AltName: Full=U5 snRNP-specific 40 kDa protein;
DE   AltName: Full=WD repeat-containing protein 57;
GN   Name=SNRNP40; Synonyms=PRP8BP, SFP38, WDR57;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   SNR48_HUMAN             Reviewed;         339 AA.
AC   Q6IEG0; A8K8P4; Q14C91; Q5T339; Q5THM1; Q5THM2; Q96MK1;
DE   RecName: Full=U11/U12 small nuclear ribonucleoprotein 48 kDa protein;
DE            Short=U11/U12 snRNP 48 kDa protein;
DE            Short=U11/U12-48K;
GN   Name=SNRNP48; Synonyms=C6orf151;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   SNRK_HUMAN              Reviewed;         765 AA.
AC   Q9NRH2; B2RAV6; Q14706; Q68D15; Q6IQ46; Q9NXI7;
DE   RecName: Full=SNF-related serine/threonine-protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=SNF1-related kinase;
GN   Name=SNRK; Synonyms=KIAA0096, SNFRK;
DR   GuidetoPHARMACOLOGY; 2202; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   SNRPA_HUMAN             Reviewed;         282 AA.
AC   P09012;
DE   RecName: Full=U1 small nuclear ribonucleoprotein A;
DE            Short=U1 snRNP A;
DE            Short=U1-A;
DE            Short=U1A;
GN   Name=SNRPA;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0017069; F:snRNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:HGNC.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   SNTA1_HUMAN             Reviewed;         505 AA.
AC   Q13424; A8K7H9; E1P5N1; Q16438;
DE   RecName: Full=Alpha-1-syntrophin;
DE   AltName: Full=59 kDa dystrophin-associated protein A1 acidic component 1;
DE   AltName: Full=Pro-TGF-alpha cytoplasmic domain-interacting protein 1;
DE            Short=TACIP1;
DE   AltName: Full=Syntrophin-1;
GN   Name=SNTA1; Synonyms=SNT1;
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0050998; F:nitric-oxide synthase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:1902083; P:negative regulation of peptidyl-cysteine S-nitrosylation; IMP:BHF-UCL.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:1902305; P:regulation of sodium ion transmembrane transport; IMP:BHF-UCL.
DR   GO; GO:0003117; P:regulation of vasoconstriction by circulating norepinephrine; IEA:Ensembl.
DR   GO; GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IMP:BHF-UCL.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IMP:BHF-UCL.
//
ID   SNTAN_HUMAN             Reviewed;         147 AA.
AC   A6NMZ2; B7FF65;
DE   RecName: Full=Sentan;
DE   AltName: Full=Protein S100-A1-like;
DE   AltName: Full=S100 calcium-binding protein A1-like;
GN   Name=SNTN; Synonyms=S100A1L;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   SNTB1_HUMAN             Reviewed;         538 AA.
AC   Q13884; A8K9E0; O14912; Q4KMG8;
DE   RecName: Full=Beta-1-syntrophin;
DE   AltName: Full=59 kDa dystrophin-associated protein A1 basic component 1;
DE            Short=DAPA1B;
DE   AltName: Full=BSYN2;
DE   AltName: Full=Syntrophin-2;
DE   AltName: Full=Tax interaction protein 43;
DE            Short=TIP-43;
GN   Name=SNTB1; Synonyms=SNT2B1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   SNTB2_HUMAN             Reviewed;         540 AA.
AC   Q13425; Q9BY09;
DE   RecName: Full=Beta-2-syntrophin;
DE   AltName: Full=59 kDa dystrophin-associated protein A1 basic component 2;
DE   AltName: Full=Syntrophin-3;
DE            Short=SNT3;
DE   AltName: Full=Syntrophin-like;
DE            Short=SNTL;
GN   Name=SNTB2; Synonyms=D16S2531E, SNT2B2, SNTL;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   SNTG1_HUMAN             Reviewed;         517 AA.
AC   Q9NSN8; Q2M3Q0; Q9NY98;
DE   RecName: Full=Gamma-1-syntrophin;
DE            Short=G1SYN;
DE   AltName: Full=Syntrophin-4;
DE            Short=SYN4;
GN   Name=SNTG1;
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007154; P:cell communication; TAS:ProtInc.
//
ID   SNTG2_HUMAN             Reviewed;         539 AA.
AC   Q9NY99; Q05AH5;
DE   RecName: Full=Gamma-2-syntrophin;
DE            Short=G2SYN;
DE   AltName: Full=Syntrophin-5;
DE            Short=SYN5;
GN   Name=SNTG2;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
//
ID   SNUFL_HUMAN             Reviewed;         121 AA.
AC   B1AK76;
DE   RecName: Full=Putative SNURF-like protein;
GN   Name=SNURFL; Synonyms=CXorf19;
//
ID   SNURF_HUMAN             Reviewed;          71 AA.
AC   Q9Y675; A6NCW2;
DE   RecName: Full=SNRPN upstream reading frame protein;
GN   Name=SNURF;
//
ID   SNUT1_HUMAN             Reviewed;         800 AA.
AC   O43290; A6NDN1; Q53GB5;
DE   RecName: Full=U4/U6.U5 tri-snRNP-associated protein 1;
DE   AltName: Full=SNU66 homolog;
DE            Short=hSnu66;
DE   AltName: Full=Squamous cell carcinoma antigen recognized by T-cells 1;
DE            Short=SART-1;
DE            Short=hSART-1;
DE   AltName: Full=U4/U6.U5 tri-snRNP-associated 110 kDa protein;
DE   AltName: Allergen=Hom s 1;
GN   Name=SART1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007050; P:cell cycle arrest; NAS:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; NAS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0045585; P:positive regulation of cytotoxic T cell differentiation; IDA:UniProtKB.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:BHF-UCL.
//
ID   SNUT2_HUMAN             Reviewed;         565 AA.
AC   Q53GS9; A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; Q6NX47; Q96RK9;
AC   Q9BV89; Q9H381; Q9P050; Q9Y310;
DE   RecName: Full=U4/U6.U5 tri-snRNP-associated protein 2;
DE   AltName: Full=Inactive ubiquitin-specific peptidase 39;
DE   AltName: Full=SAD1 homolog;
DE   AltName: Full=U4/U6.U5 tri-snRNP-associated 65 kDa protein;
DE            Short=65K;
GN   Name=USP39; ORFNames=CGI-21, HSPC332, PRO2855;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0000245; P:spliceosomal complex assembly; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   SNW1_HUMAN              Reviewed;         536 AA.
AC   Q13573; A8K8A9; Q13483; Q32N03; Q5D0D6;
DE   RecName: Full=SNW domain-containing protein 1;
DE   AltName: Full=Nuclear protein SkiP;
DE   AltName: Full=Nuclear receptor coactivator NCoA-62;
DE   AltName: Full=Ski-interacting protein;
GN   Name=SNW1; Synonyms=SKIIP, SKIP;
DR   GO; GO:0005112; F:Notch binding; IPI:UniProtKB.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042974; F:retinoic acid receptor binding; IDA:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0070564; P:positive regulation of vitamin D receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048385; P:regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0070562; P:regulation of vitamin D receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SNX10_HUMAN             Reviewed;         201 AA.
AC   Q9Y5X0; E9PFH5; Q8IYT5;
DE   RecName: Full=Sorting nexin-10;
GN   Name=SNX10;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IMP:UniProtKB.
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.
DR   GO; GO:0071539; P:protein localization to centrosome; IMP:UniProtKB.
DR   GO; GO:0061512; P:protein localization to cilium; IMP:UniProtKB.
//
ID   SNX11_HUMAN             Reviewed;         270 AA.
AC   Q9Y5W9; B3KRL6; D3DTV0; Q53YC0; Q9H885;
DE   RecName: Full=Sorting nexin-11;
GN   Name=SNX11;
DR   GO; GO:1901981; F:phosphatidylinositol phosphate binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0016050; P:vesicle organization; IMP:UniProtKB.
//
ID   SNX12_HUMAN             Reviewed;         172 AA.
AC   Q9UMY4; F8W8K5; Q8WUG9;
DE   RecName: Full=Sorting nexin-12;
GN   Name=SNX12;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
//
ID   SNX13_HUMAN             Reviewed;         968 AA.
AC   Q9Y5W8; B2RCI9; O94821; Q8WVZ2; Q8WXH8;
DE   RecName: Full=Sorting nexin-13;
DE   AltName: Full=RGS domain- and PHOX domain-containing protein;
DE   AltName: Full=RGS-PX1;
GN   Name=SNX13; Synonyms=KIAA0713;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   SNX14_HUMAN             Reviewed;         946 AA.
AC   Q9Y5W7; B4DI55; Q4VBR3; Q5TCF9; Q5TCG0; Q6NUI7; Q6PI37; Q9BSD1;
DE   RecName: Full=Sorting nexin-14;
GN   Name=SNX14;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   SNX15_HUMAN             Reviewed;         342 AA.
AC   Q9NRS6; E5KQS6; Q9NRS5;
DE   RecName: Full=Sorting nexin-15;
GN   Name=SNX15;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
//
ID   SNX16_HUMAN             Reviewed;         344 AA.
AC   P57768; A8K4D8; Q658L0; Q8N4U3;
DE   RecName: Full=Sorting nexin-16;
GN   Name=SNX16;
DR   GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.
//
ID   SNX17_HUMAN             Reviewed;         470 AA.
AC   Q15036; B4DQM7; Q53HN7; Q6IAS3;
DE   RecName: Full=Sorting nexin-17;
GN   Name=SNX17; Synonyms=KIAA0064;
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:UniProtKB.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; NAS:UniProtKB.
DR   GO; GO:0006707; P:cholesterol catabolic process; IC:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0030100; P:regulation of endocytosis; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SNX18_HUMAN             Reviewed;         628 AA.
AC   Q96RF0; B4E2B3; H7BXX3; Q05BB3; Q0VG02;
DE   RecName: Full=Sorting nexin-18;
DE   AltName: Full=SH3 and PX domain-containing protein 3B;
DE   AltName: Full=Sorting nexin-associated Golgi protein 1;
GN   Name=SNX18; Synonyms=SH3PXD3B, SNAG1;
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:FlyBase.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0036089; P:cleavage furrow formation; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IDA:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.
//
ID   SNX19_HUMAN             Reviewed;         992 AA.
AC   Q92543;
DE   RecName: Full=Sorting nexin-19;
GN   Name=SNX19; Synonyms=KIAA0254;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SNX1_HUMAN              Reviewed;         522 AA.
AC   Q13596; A6NM19; A8K6T7; H0Y2M5; O60750; O60751; Q6ZRJ8;
DE   RecName: Full=Sorting nexin-1;
GN   Name=SNX1;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034498; P:early endosome to Golgi transport; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
//
ID   SNX20_HUMAN             Reviewed;         316 AA.
AC   Q7Z614; A8K9D5; Q08E98; Q6P4H2; Q8IV59;
DE   RecName: Full=Sorting nexin-20;
DE   AltName: Full=Selectin ligand-interactor cytoplasmic 1;
GN   Name=SNX20; Synonyms=SLIC1;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SNX21_HUMAN             Reviewed;         373 AA.
AC   Q969T3; Q5JZH5; Q5JZH6; Q5JZH7; Q8WUR6; Q9BR16;
DE   RecName: Full=Sorting nexin-21;
DE   AltName: Full=Sorting nexin L;
DE            Short=SNX-L;
GN   Name=SNX21; Synonyms=C20orf161, SNXL;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SNX22_HUMAN             Reviewed;         193 AA.
AC   Q96L94; Q9H844;
DE   RecName: Full=Sorting nexin-22;
GN   Name=SNX22;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SNX24_HUMAN             Reviewed;         169 AA.
AC   Q9Y343; Q6UY33;
DE   RecName: Full=Sorting nexin-24;
GN   Name=SNX24; ORFNames=SBBI31, UNQ654/PRO1284;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SNX25_HUMAN             Reviewed;         840 AA.
AC   Q9H3E2; Q3ZT30;
DE   RecName: Full=Sorting nexin-25;
GN   Name=SNX25; ORFNames=MSTP043;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IMP:UniProt.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032801; P:receptor catabolic process; IMP:UniProt.
DR   GO; GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
//
ID   SNX27_HUMAN             Reviewed;         541 AA.
AC   Q96L92; Q32Q36; Q4AEJ5; Q5VWB0; Q5VWB1; Q5VWB2; Q6IPP6; Q86UB1;
AC   Q96D79; Q9H3K8;
DE   RecName: Full=Sorting nexin-27;
GN   Name=SNX27; Synonyms=KIAA0488; ORFNames=My014;
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
DR   GO; GO:0001770; P:establishment of natural killer cell polarity; TAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:1990126; P:retrograde transport, endosome to plasma membrane; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SNX29_HUMAN             Reviewed;         813 AA.
AC   Q8TEQ0; B5MDW2; Q8N2X2; Q9HA26;
DE   RecName: Full=Sorting nexin-29;
DE   AltName: Full=RUN domain-containing protein 2A;
GN   Name=SNX29; Synonyms=RUNDC2A;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
//
ID   SNX2_HUMAN              Reviewed;         519 AA.
AC   O60749; B3KN44; B4DEK4; B7Z408; O43650; P82862; Q53XK8; Q597H6;
AC   Q9BTS8;
DE   RecName: Full=Sorting nexin-2;
DE   AltName: Full=Transformation-related gene 9 protein;
DE            Short=TRG-9;
GN   Name=SNX2; ORFNames=TRG9;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   SNX30_HUMAN             Reviewed;         437 AA.
AC   Q5VWJ9;
DE   RecName: Full=Sorting nexin-30;
GN   Name=SNX30;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
//
ID   SNX31_HUMAN             Reviewed;         440 AA.
AC   Q8N9S9; C9J6L9; Q8N0U9;
DE   RecName: Full=Sorting nexin-31;
GN   Name=SNX31;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SNX32_HUMAN             Reviewed;         403 AA.
AC   Q86XE0; Q8IW53; Q96NG4;
DE   RecName: Full=Sorting nexin-32;
DE   AltName: Full=Sorting nexin-6B;
GN   Name=SNX32; Synonyms=SNX6B;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
//
ID   SNX33_HUMAN             Reviewed;         574 AA.
AC   Q8WV41; B1NM17;
DE   RecName: Full=Sorting nexin-33;
DE   AltName: Full=SH3 and PX domain-containing protein 3;
GN   Name=SNX33; Synonyms=SH3PX3, SH3PXD3C, SNX30;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0036089; P:cleavage furrow formation; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0044351; P:macropinocytosis; IMP:UniProtKB.
DR   GO; GO:0097320; P:membrane tubulation; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:UniProtKB.
//
ID   SNX3_HUMAN              Reviewed;         162 AA.
AC   O60493; A8K0B1; E1P5E4; E1P5E5; O60718; Q4TT29; Q4TT31; Q5JXJ7;
AC   Q5JXJ8; Q96AP9; Q9C0J5; Q9NU45;
DE   RecName: Full=Sorting nexin-3;
DE   AltName: Full=Protein SDP3;
GN   Name=SNX3;
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
//
ID   SNX4_HUMAN              Reviewed;         450 AA.
AC   O95219; B3KMH0; D3DNA3;
DE   RecName: Full=Sorting nexin-4;
GN   Name=SNX4;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032456; P:endocytic recycling; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
//
ID   SNX5_HUMAN              Reviewed;         404 AA.
AC   Q9Y5X3; B7ZKN3; D3DW26; Q52LC4; Q9BWP0;
DE   RecName: Full=Sorting nexin-5;
GN   Name=SNX5;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0006907; P:pinocytosis; IDA:UniProtKB.
//
ID   SNX6_HUMAN              Reviewed;         406 AA.
AC   Q9UNH7; C0H5W9; Q9Y449;
DE   RecName: Full=Sorting nexin-6;
DE   AltName: Full=TRAF4-associated factor 2;
DE   Contains:
DE     RecName: Full=Sorting nexin-6, N-terminally processed;
GN   Name=SNX6;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:HGNC.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   SNX7_HUMAN              Reviewed;         387 AA.
AC   Q9UNH6; A8KAF3; D3DT50; Q53FQ3; Q5VT09; Q5VT10; Q86U82; Q8WVD4;
AC   Q96FW9; Q9Y3Z7;
DE   RecName: Full=Sorting nexin-7;
GN   Name=SNX7;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
//
ID   SNX8_HUMAN              Reviewed;         465 AA.
AC   Q9Y5X2; A4D207; Q96I67;
DE   RecName: Full=Sorting nexin-8;
GN   Name=SNX8;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034498; P:early endosome to Golgi transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
//
ID   SNX9_HUMAN              Reviewed;         595 AA.
AC   Q9Y5X1; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20;
DE   RecName: Full=Sorting nexin-9;
DE   AltName: Full=SH3 and PX domain-containing protein 1;
DE            Short=Protein SDP1;
DE   AltName: Full=SH3 and PX domain-containing protein 3A;
GN   Name=SNX9; Synonyms=SH3PX1, SH3PXD3A;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0036089; P:cleavage furrow formation; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IMP:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0060988; P:lipid tube assembly; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.
//
ID   SN_HUMAN                Reviewed;        1709 AA.
AC   Q9BZZ2; Q96DL4; Q9GZS5; Q9H1H6; Q9H1H7; Q9H7L7;
DE   RecName: Full=Sialoadhesin;
DE   AltName: Full=Sialic acid-binding Ig-like lectin 1;
DE            Short=Siglec-1;
DE   AltName: CD_antigen=CD169;
DE   Flags: Precursor;
GN   Name=SIGLEC1; Synonyms=SN;
DR   GO; GO:0030246; F:carbohydrate binding; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0070234; P:positive regulation of T cell apoptotic process; IEA:Ensembl.
//
ID   SO1A2_HUMAN             Reviewed;         670 AA.
AC   P46721; Q9UGP7; Q9UL38;
DE   RecName: Full=Solute carrier organic anion transporter family member 1A2;
DE   AltName: Full=OATP-A;
DE   AltName: Full=Organic anion-transporting polypeptide 1;
DE            Short=OATP-1;
DE   AltName: Full=Sodium-independent organic anion transporter;
DE   AltName: Full=Solute carrier family 21 member 3;
GN   Name=SLCO1A2; Synonyms=OATP, OATP1, OATP1A2, SLC21A3;
DR   GuidetoPHARMACOLOGY; 1219; -.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0015711; P:organic anion transport; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO1B1_HUMAN             Reviewed;         691 AA.
AC   Q9Y6L6; B2R7G2; Q29R64; Q9NQ37; Q9UBF3; Q9UH89;
DE   RecName: Full=Solute carrier organic anion transporter family member 1B1;
DE   AltName: Full=Liver-specific organic anion transporter 1;
DE            Short=LST-1;
DE   AltName: Full=OATP-C;
DE   AltName: Full=Sodium-independent organic anion-transporting polypeptide 2;
DE            Short=OATP-2;
DE   AltName: Full=Solute carrier family 21 member 6;
GN   Name=SLCO1B1; Synonyms=LST1, OATP1B1, OATP2, OATPC, SLC21A6;
DR   GuidetoPHARMACOLOGY; 1220; -.
DR   GO; GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0015711; P:organic anion transport; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO1B3_HUMAN             Reviewed;         702 AA.
AC   Q9NPD5;
DE   RecName: Full=Solute carrier organic anion transporter family member 1B3;
DE   AltName: Full=Liver-specific organic anion transporter 2;
DE            Short=LST-2;
DE   AltName: Full=Organic anion transporter 8;
DE   AltName: Full=Organic anion-transporting polypeptide 8;
DE            Short=OATP-8;
DE   AltName: Full=Solute carrier family 21 member 8;
GN   Name=SLCO1B3; Synonyms=LST2, OATP1B3, OATP8,SLC21A8;
DR   GuidetoPHARMACOLOGY; 1221; -.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; TAS:Reactome.
DR   GO; GO:0015711; P:organic anion transport; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO1B7_HUMAN             Reviewed;         640 AA.
AC   G3V0H7; Q71QF0;
DE   RecName: Full=Putative solute carrier organic anion transporter family member 1B7;
DE   AltName: Full=Liver-specific organic anion transporter 3;
DE            Short=LST-3;
GN   Name=SLCO1B7; Synonyms=LST3, LST3TM12;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   SO1C1_HUMAN             Reviewed;         712 AA.
AC   Q9NYB5; B7Z251; B7Z3Q3; B7Z8P1; F5GZD6; Q5JPA4;
DE   RecName: Full=Solute carrier organic anion transporter family member 1C1;
DE   AltName: Full=Organic anion transporter F;
DE            Short=OATP-F;
DE   AltName: Full=Organic anion transporter polypeptide-related protein 5;
DE            Short=OAT-RP-5;
DE            Short=OATPRP5;
DE   AltName: Full=Organic anion-transporting polypeptide 14;
DE            Short=OATP-14;
DE   AltName: Full=Solute carrier family 21 member 14;
DE   AltName: Full=Thyroxine transporter;
GN   Name=SLCO1C1; Synonyms=OATP14, OATP1C1, OATPF, SLC21A14;
DR   GuidetoPHARMACOLOGY; 1222; -.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO2A1_HUMAN             Reviewed;         643 AA.
AC   Q92959; Q86V98; Q8IUN2;
DE   RecName: Full=Solute carrier organic anion transporter family member 2A1;
DE   AltName: Full=Prostaglandin transporter;
DE            Short=PGT;
DE   AltName: Full=Solute carrier family 21 member 2;
GN   Name=SLCO2A1; Synonyms=OATP2A1, SLC21A2;
DR   GuidetoPHARMACOLOGY; 1223; -.
DR   GO; GO:0005319; F:lipid transporter activity; TAS:ProtInc.
DR   GO; GO:0015132; F:prostaglandin transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0006869; P:lipid transport; TAS:ProtInc.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO2B1_HUMAN             Reviewed;         709 AA.
AC   O94956; A8K2G9; B4DGA9; B4DTB0; E7ERN5; E9PPU8; Q9H2Z0; Q9UFU1;
DE   RecName: Full=Solute carrier organic anion transporter family member 2B1;
DE   AltName: Full=Organic anion transporter B;
DE            Short=OATP-B;
DE   AltName: Full=Organic anion transporter polypeptide-related protein 2;
DE            Short=OATP-RP2;
DE            Short=OATPRP2;
DE   AltName: Full=Solute carrier family 21 member 9;
GN   Name=SLCO2B1; Synonyms=KIAA0880, OATP2B1, OATPB, SLC21A9;
DR   GuidetoPHARMACOLOGY; 1224; -.
DR   GO; GO:0015125; F:bile acid transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0008514; F:organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0015347; F:sodium-independent organic anion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0071718; P:sodium-independent icosanoid transport; IEA:Ensembl.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO3A1_HUMAN             Reviewed;         710 AA.
AC   Q9UIG8; A8K4A7; B3KPY5; B3KUR7; C6G486; Q9BW73; Q9GZV2;
DE   RecName: Full=Solute carrier organic anion transporter family member 3A1;
DE            Short=OATP3A1;
DE   AltName: Full=Organic anion transporter polypeptide-related protein 3;
DE            Short=OATP-RP3;
DE            Short=OATPRP3;
DE   AltName: Full=Organic anion-transporting polypeptide D;
DE            Short=OATP-D;
DE   AltName: Full=PGE1 transporter;
DE   AltName: Full=Sodium-independent organic anion transporter D;
DE   AltName: Full=Solute carrier family 21 member 11;
GN   Name=SLCO3A1; Synonyms=OATP3A1, OATPD, SLC21A11;
DR   GuidetoPHARMACOLOGY; 1225; -.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO4A1_HUMAN             Reviewed;         722 AA.
AC   Q96BD0; Q9H4T7; Q9H4T8; Q9H8P2; Q9NWX8; Q9UI35; Q9UIG7;
DE   RecName: Full=Solute carrier organic anion transporter family member 4A1;
DE            Short=OATP4A1;
DE   AltName: Full=Colon organic anion transporter;
DE   AltName: Full=Organic anion transporter polypeptide-related protein 1;
DE            Short=OATP-RP1;
DE            Short=OATPRP1;
DE            Short=POAT;
DE   AltName: Full=Organic anion-transporting polypeptide E;
DE            Short=OATP-E;
DE   AltName: Full=Sodium-independent organic anion transporter E;
DE   AltName: Full=Solute carrier family 21 member 12;
GN   Name=SLCO4A1; Synonyms=OATP1, OATP4A1, OATPE, SLC21A12;
DR   GuidetoPHARMACOLOGY; 1226; -.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO4C1_HUMAN             Reviewed;         724 AA.
AC   Q6ZQN7; Q86UG5;
DE   RecName: Full=Solute carrier organic anion transporter family member 4C1;
DE   AltName: Full=OATP-H;
DE   AltName: Full=Organic anion transporter M1;
DE            Short=OATP-M1;
DE   AltName: Full=Solute carrier family 21 member 20;
GN   Name=SLCO4C1; Synonyms=OATP4C1, OATPX, SLC21A20;
DR   GuidetoPHARMACOLOGY; 1227; -.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0043252; P:sodium-independent organic anion transport; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SO5A1_HUMAN             Reviewed;         848 AA.
AC   Q9H2Y9; A4QPC2; B2RPF7; B3KMU7; E9PKK5; G3V1C0;
DE   RecName: Full=Solute carrier organic anion transporter family member 5A1;
DE   AltName: Full=Organic anion transporter polypeptide-related protein 4;
DE            Short=OATP-RP4;
DE            Short=OATPRP4;
DE   AltName: Full=Solute carrier family 21 member 15;
GN   Name=SLCO5A1; Synonyms=OATP5A1, SLC21A15;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   SO6A1_HUMAN             Reviewed;         719 AA.
AC   Q86UG4; A6NHC1; Q6ZMY5; Q86UV2; Q8IYU5;
DE   RecName: Full=Solute carrier organic anion transporter family member 6A1;
DE   AltName: Full=Cancer/testis antigen 48;
DE            Short=CT48;
DE   AltName: Full=Gonad-specific transporter;
DE            Short=GST;
DE   AltName: Full=Organic anion-transporting polypeptide 6A1;
DE   AltName: Full=Organic anion-transporting polypeptide I;
DE            Short=OATP-I;
DE   AltName: Full=Solute carrier family 21 member 19;
GN   Name=SLCO6A1; Synonyms=OATP6A1, SLC21A19;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   SOAT1_HUMAN             Reviewed;         550 AA.
AC   P35610; A6NC40; A8K3P4; A9Z1V7; B4DU95; Q5T0X4; Q8N1E4;
DE   RecName: Full=Sterol O-acyltransferase 1;
DE            EC=2.3.1.26;
DE   AltName: Full=Acyl-coenzyme A:cholesterol acyltransferase 1;
DE            Short=ACAT-1;
DE   AltName: Full=Cholesterol acyltransferase 1;
GN   Name=SOAT1; Synonyms=ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0034736; F:cholesterol O-acyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004772; F:sterol O-acyltransferase activity; IMP:BHF-UCL.
DR   GO; GO:0033344; P:cholesterol efflux; IMP:BHF-UCL.
DR   GO; GO:0034435; P:cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; TAS:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0010878; P:cholesterol storage; IMP:BHF-UCL.
DR   GO; GO:0010742; P:macrophage derived foam cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0042986; P:positive regulation of amyloid precursor protein biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; IMP:BHF-UCL.
//
ID   SOAT2_HUMAN             Reviewed;         522 AA.
AC   O75908; Q4VB99; Q96TD4; Q9UNR2;
DE   RecName: Full=Sterol O-acyltransferase 2;
DE            EC=2.3.1.26;
DE   AltName: Full=Acyl-coenzyme A:cholesterol acyltransferase 2;
DE            Short=ACAT-2;
DE   AltName: Full=Cholesterol acyltransferase 2;
GN   Name=SOAT2; Synonyms=ACACT2, ACAT2;
DR   GO; GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
DR   GO; GO:0034736; F:cholesterol O-acyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0000062; F:fatty-acyl-CoA binding; IDA:BHF-UCL.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; TAS:ProtInc.
DR   GO; GO:0033344; P:cholesterol efflux; IMP:BHF-UCL.
DR   GO; GO:0034435; P:cholesterol esterification; IDA:BHF-UCL.
DR   GO; GO:0042632; P:cholesterol homeostasis; TAS:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030299; P:intestinal cholesterol absorption; IC:BHF-UCL.
DR   GO; GO:0010742; P:macrophage derived foam cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0034379; P:very-low-density lipoprotein particle assembly; IMP:BHF-UCL.
//
ID   SOAT_HUMAN              Reviewed;         377 AA.
AC   Q3KNW5; Q70EX7;
DE   RecName: Full=Solute carrier family 10 member 6;
DE   AltName: Full=Sodium-dependent organic anion transporter;
GN   Name=SLC10A6; Synonyms=SOAT;
DR   GO; GO:0008508; F:bile acid:sodium symporter activity; IEA:InterPro.
DR   GO; GO:0043250; F:sodium-dependent organic anion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0043251; P:sodium-dependent organic anion transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   SOBP_HUMAN              Reviewed;         873 AA.
AC   A7XYQ1; B0QZ12; Q5BJD4; Q8N2B2;
DE   RecName: Full=Sine oculis-binding protein homolog;
DE   AltName: Full=Jackson circler protein 1;
GN   Name=SOBP; Synonyms=JXC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032184; F:SUMO polymer binding; IDA:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   SOCS1_HUMAN             Reviewed;         211 AA.
AC   O15524; O15097; Q9NSA7;
DE   RecName: Full=Suppressor of cytokine signaling 1;
DE            Short=SOCS-1;
DE   AltName: Full=JAK-binding protein;
DE            Short=JAB;
DE   AltName: Full=STAT-induced STAT inhibitor 1;
DE            Short=SSI-1;
DE   AltName: Full=Tec-interacting protein 3;
DE            Short=TIP-3;
GN   Name=SOCS1; Synonyms=SSI1, TIP3;
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0019210; F:kinase inhibitor activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0046426; P:negative regulation of JAK-STAT cascade; ISS:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   SOCS2_HUMAN             Reviewed;         198 AA.
AC   O14508; A8K3D1; O14542; O95102; Q9UKS5;
DE   RecName: Full=Suppressor of cytokine signaling 2;
DE            Short=SOCS-2;
DE   AltName: Full=Cytokine-inducible SH2 protein 2;
DE            Short=CIS-2;
DE   AltName: Full=STAT-induced STAT inhibitor 2;
DE            Short=SSI-2;
GN   Name=SOCS2; Synonyms=CIS2, SSI2, STATI2;
DR   GO; GO:0005131; F:growth hormone receptor binding; NAS:UniProtKB.
DR   GO; GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0008269; F:JAK pathway signal transduction adaptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IDA:BHF-UCL.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0046425; P:regulation of JAK-STAT cascade; TAS:GOC.
DR   GO; GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
//
ID   SOCS3_HUMAN             Reviewed;         225 AA.
AC   O14543; O14509;
DE   RecName: Full=Suppressor of cytokine signaling 3;
DE            Short=SOCS-3;
DE   AltName: Full=Cytokine-inducible SH2 protein 3;
DE            Short=CIS-3;
DE   AltName: Full=STAT-induced STAT inhibitor 3;
DE            Short=SSI-3;
GN   Name=SOCS3; Synonyms=CIS3, SSI3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060708; P:spongiotrophoblast differentiation; IEA:Ensembl.
DR   GO; GO:0060707; P:trophoblast giant cell differentiation; IEA:Ensembl.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   SOCS4_HUMAN             Reviewed;         440 AA.
AC   Q8WXH5;
DE   RecName: Full=Suppressor of cytokine signaling 4;
DE            Short=SOCS-4;
DE   AltName: Full=Suppressor of cytokine signaling 7;
DE            Short=SOCS-7;
GN   Name=SOCS4; Synonyms=SOCS7;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   SOCS5_HUMAN             Reviewed;         536 AA.
AC   O75159; Q53SD4; Q8IYZ4;
DE   RecName: Full=Suppressor of cytokine signaling 5;
DE            Short=SOCS-5;
DE   AltName: Full=Cytokine-inducible SH2 protein 6;
DE            Short=CIS-6;
DE   AltName: Full=Cytokine-inducible SH2-containing protein 5;
GN   Name=SOCS5; Synonyms=CIS6, CISH5, CISH6, KIAA0671;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
DR   GO; GO:0016049; P:cell growth; NAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0009968; P:negative regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0045629; P:negative regulation of T-helper 2 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045627; P:positive regulation of T-helper 1 cell differentiation; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   SOCS7_HUMAN             Reviewed;         581 AA.
AC   O14512; A2VCU2; Q0IJ63;
DE   RecName: Full=Suppressor of cytokine signaling 7;
DE            Short=SOCS-7;
DE   AltName: Full=Nck, Ash and phospholipase C gamma-binding protein;
DE   AltName: Full=Nck-associated protein 4;
DE            Short=NAP-4;
GN   Name=SOCS7; Synonyms=NAP4, SOCS6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; NAS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   SOCS6_HUMAN             Reviewed;         535 AA.
AC   O14544; Q8WUM3;
DE   RecName: Full=Suppressor of cytokine signaling 6;
DE            Short=SOCS-6;
DE   AltName: Full=Cytokine-inducible SH2 protein 4;
DE            Short=CIS-4;
DE   AltName: Full=Suppressor of cytokine signaling 4;
DE            Short=SOCS-4;
GN   Name=SOCS6; Synonyms=CIS4, SOCS4;
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IEA:Ensembl.
DR   GO; GO:0010498; P:proteasomal protein catabolic process; IMP:MGI.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   SODC_HUMAN              Reviewed;         154 AA.
AC   P00441; A6NHJ0; D3DSE4; Q16669; Q16711; Q16838; Q16839; Q16840;
AC   Q6NR85;
DE   RecName: Full=Superoxide dismutase [Cu-Zn];
DE            EC=1.15.1.1;
DE   AltName: Full=Superoxide dismutase 1;
DE            Short=hSod1;
GN   Name=SOD1;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0030346; F:protein phosphatase 2B binding; IDA:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.
DR   GO; GO:0004784; F:superoxide dismutase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:UniProtKB.
DR   GO; GO:0008089; P:anterograde axon cargo transport; ISS:BHF-UCL.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; ISS:UniProtKB.
DR   GO; GO:0060088; P:auditory receptor cell stereocilium organization; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007569; P:cell aging; IMP:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; ISS:UniProtKB.
DR   GO; GO:0007566; P:embryo implantation; ISS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.
DR   GO; GO:0060047; P:heart contraction; IDA:UniProtKB.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; ISS:UniProtKB.
DR   GO; GO:0002262; P:myeloid cell homeostasis; ISS:UniProtKB.
DR   GO; GO:0045541; P:negative regulation of cholesterol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0060052; P:neurofilament cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
DR   GO; GO:0032287; P:peripheral nervous system myelin maintenance; ISS:UniProtKB.
DR   GO; GO:0001890; P:placenta development; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IC:UniProtKB.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:1902177; P:positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; IDA:UniProtKB.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:UniProtKB.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IMP:UniProtKB.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.
DR   GO; GO:0046620; P:regulation of organ growth; NAS:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.
DR   GO; GO:0033081; P:regulation of T cell differentiation in thymus; NAS:UniProtKB.
DR   GO; GO:0060087; P:relaxation of vascular smooth muscle; ISS:UniProtKB.
DR   GO; GO:0019430; P:removal of superoxide radicals; ISS:UniProtKB.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; ISS:UniProtKB.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; ISS:UniProtKB.
DR   GO; GO:0045471; P:response to ethanol; ISS:UniProtKB.
DR   GO; GO:0009408; P:response to heat; ISS:UniProtKB.
DR   GO; GO:0042542; P:response to hydrogen peroxide; ISS:UniProtKB.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IDA:UniProtKB.
DR   GO; GO:0000303; P:response to superoxide; IDA:UniProtKB.
DR   GO; GO:0001895; P:retina homeostasis; ISS:UniProtKB.
DR   GO; GO:0008090; P:retrograde axon cargo transport; ISS:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0042554; P:superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
DR   GO; GO:0048538; P:thymus development; NAS:UniProtKB.
DR   GO; GO:0019226; P:transmission of nerve impulse; ISS:UniProtKB.
//
ID   SODE_HUMAN              Reviewed;         240 AA.
AC   P08294; Q5U781; Q6FHA2;
DE   RecName: Full=Extracellular superoxide dismutase [Cu-Zn];
DE            Short=EC-SOD;
DE            EC=1.15.1.1;
DE   Flags: Precursor;
GN   Name=SOD3;
DR   GO; GO:0005507; F:copper ion binding; IBA:RefGenome.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004784; F:superoxide dismutase activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; IBA:RefGenome.
DR   GO; GO:0019430; P:removal of superoxide radicals; IBA:RefGenome.
DR   GO; GO:0046688; P:response to copper ion; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   SODM_HUMAN              Reviewed;         222 AA.
AC   P04179; B2R7R1; B3KUK2; B4DL20; B4E3K9; E1P5A9; P78434; Q16792;
AC   Q5TCM1; Q96EE6; Q9P2Z3;
DE   RecName: Full=Superoxide dismutase [Mn], mitochondrial;
DE            EC=1.15.1.1;
DE   Flags: Precursor;
GN   Name=SOD2;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0019825; F:oxygen binding; IEA:Ensembl.
DR   GO; GO:0004784; F:superoxide dismutase activity; IDA:UniProtKB.
DR   GO; GO:0001315; P:age-dependent response to reactive oxygen species; IMP:UniProtKB.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0003032; P:detection of oxygen; IEA:Ensembl.
DR   GO; GO:0048773; P:erythrophore differentiation; IEA:Ensembl.
DR   GO; GO:0006749; P:glutathione metabolic process; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0050665; P:hydrogen peroxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IGI:BHF-UCL.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0032364; P:oxygen homeostasis; IMP:BHF-UCL.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0008217; P:regulation of blood pressure; ISS:BHF-UCL.
DR   GO; GO:0050790; P:regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; ISS:BHF-UCL.
DR   GO; GO:0019430; P:removal of superoxide radicals; IMP:BHF-UCL.
DR   GO; GO:0022904; P:respiratory electron transport chain; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0055093; P:response to hyperoxia; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0033591; P:response to L-ascorbic acid; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IEA:Ensembl.
DR   GO; GO:0010269; P:response to selenium ion; IEA:Ensembl.
DR   GO; GO:0034021; P:response to silicon dioxide; IEA:Ensembl.
DR   GO; GO:0000303; P:response to superoxide; IMP:BHF-UCL.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0042554; P:superoxide anion generation; IEA:Ensembl.
DR   GO; GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
DR   GO; GO:0003069; P:vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure; ISS:BHF-UCL.
//
ID   SOGA1_HUMAN             Reviewed;        1423 AA.
AC   O94964; A6NK10; Q14DB2; Q5JW51; Q6ZTG8;
DE   RecName: Full=Protein SOGA1;
DE   AltName: Full=SOGA family member 1;
DE   AltName: Full=Suppressor of glucose by autophagy;
DE   AltName: Full=Suppressor of glucose, autophagy-associated protein 1;
DE   Contains:
DE     RecName: Full=N-terminal form;
DE   Contains:
DE     RecName: Full=C-terminal 80 kDa form;
DE              Short=80-kDa SOGA fragment;
GN   Name=SOGA1; Synonyms=C20orf117, KIAA0889, SOGA;
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:UniProt.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProt.
DR   GO; GO:0010506; P:regulation of autophagy; ISS:UniProtKB.
//
ID   SOGA3_HUMAN             Reviewed;         947 AA.
AC   Q5TF21;
DE   RecName: Full=Protein SOGA3;
DE   Flags: Precursor;
GN   Name=SOGA3; Synonyms=C6orf174;
DR   GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
//
ID   SOLH1_HUMAN             Reviewed;         328 AA.
AC   Q5JUK2; C9JG81; Q5EE14; Q5EGC2; Q8NEE3;
DE   RecName: Full=Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1;
GN   Name=SOHLH1; Synonyms=C9orf157, NOHLH, TEB2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOLH2_HUMAN             Reviewed;         425 AA.
AC   Q9NX45; B4DX90; Q5EGC3; Q8TC74; Q96QX4;
DE   RecName: Full=Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2;
GN   Name=SOHLH2; Synonyms=TEB1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0048477; P:oogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOM2_HUMAN              Reviewed;         217 AA.
AC   P01242; B1A4H5; B1A4H7; O14643; O14644; P09587;
DE   RecName: Full=Growth hormone variant;
DE            Short=GH-V;
DE   AltName: Full=Growth hormone 2;
DE   AltName: Full=Placenta-specific growth hormone;
DE   Flags: Precursor;
GN   Name=GH2;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
//
ID   SOMA_HUMAN              Reviewed;         217 AA.
AC   P01241; A6NEF6; Q14405; Q16631; Q5EB53; Q9HBZ1; Q9UMJ7; Q9UNL5;
DE   RecName: Full=Somatotropin;
DE   AltName: Full=Growth hormone;
DE            Short=GH;
DE            Short=GH-N;
DE   AltName: Full=Growth hormone 1;
DE   AltName: Full=Pituitary growth hormone;
DE   Flags: Precursor;
GN   Name=GH1;
DR   GO; GO:0008083; F:growth factor activity; IPI:BHF-UCL.
DR   GO; GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005148; F:prolactin receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070977; P:bone maturation; IDA:BHF-UCL.
DR   GO; GO:0015758; P:glucose transport; IDA:MGI.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; IDA:BHF-UCL.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0010535; P:positive regulation of activation of JAK2 kinase activity; IDA:BHF-UCL.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0046427; P:positive regulation of JAK-STAT cascade; IDA:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; TAS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IDA:BHF-UCL.
DR   GO; GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; IDA:BHF-UCL.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
//
ID   SON_HUMAN               Reviewed;        2426 AA.
AC   P18583; D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; O14487;
AC   O95981; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0;
DE   RecName: Full=Protein SON;
DE   AltName: Full=Bax antagonist selected in saccharomyces 1;
DE            Short=BASS1;
DE   AltName: Full=Negative regulatory element-binding protein;
DE            Short=NRE-binding protein;
DE   AltName: Full=Protein DBP-5;
DE   AltName: Full=SON3;
GN   Name=SON; Synonyms=C21orf50, DBP5, KIAA1019, NREBP;
GN   ORFNames=HSPC310, HSPC312;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:UniProtKB.
DR   GO; GO:0043484; P:regulation of RNA splicing; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SORC1_HUMAN             Reviewed;        1168 AA.
AC   Q8WY21; A2RRF4; Q59GG7; Q5JVT7; Q5JVT8; Q5VY14; Q86WQ1; Q86WQ2;
AC   Q9H1Y1; Q9H1Y2;
DE   RecName: Full=VPS10 domain-containing receptor SorCS1;
DE            Short=hSorCS;
DE   Flags: Precursor;
GN   Name=SORCS1; Synonyms=SORCS;
DR   GO; GO:0008188; F:neuropeptide receptor activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   SORC2_HUMAN             Reviewed;        1159 AA.
AC   Q96PQ0; Q9P2L7;
DE   RecName: Full=VPS10 domain-containing receptor SorCS2;
DE   Flags: Precursor;
GN   Name=SORCS2; Synonyms=KIAA1329;
DR   GO; GO:0008188; F:neuropeptide receptor activity; NAS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   SORC3_HUMAN             Reviewed;        1222 AA.
AC   Q9UPU3; Q5VXF9; Q9NQJ2;
DE   RecName: Full=VPS10 domain-containing receptor SorCS3;
DE   Flags: Precursor;
GN   Name=SORCS3; Synonyms=KIAA1059;
DR   GO; GO:0008188; F:neuropeptide receptor activity; NAS:UniProtKB.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; NAS:UniProtKB.
//
ID   SORCN_HUMAN             Reviewed;         198 AA.
AC   P30626; A8MTH6; B4DKK2; D6W5Q0;
DE   RecName: Full=Sorcin;
DE   AltName: Full=22 kDa protein;
DE   AltName: Full=CP-22;
DE            Short=CP22;
DE   AltName: Full=V19;
GN   Name=SRI;
DR   GO; GO:0005246; F:calcium channel regulator activity; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0044325; F:ion channel binding; TAS:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0001508; P:action potential; TAS:ProtInc.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; TAS:ProtInc.
DR   GO; GO:0006880; P:intracellular sequestering of iron ion; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0010459; P:negative regulation of heart rate; IMP:BHF-UCL.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; IDA:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IMP:BHF-UCL.
DR   GO; GO:0086004; P:regulation of cardiac muscle cell contraction; IMP:BHF-UCL.
DR   GO; GO:0010649; P:regulation of cell communication by electrical coupling; TAS:BHF-UCL.
DR   GO; GO:1901844; P:regulation of cell communication by electrical coupling involved in cardiac conduction; IMP:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:1901841; P:regulation of high voltage-gated calcium channel activity; IMP:BHF-UCL.
DR   GO; GO:1901077; P:regulation of relaxation of muscle; IMP:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; TAS:BHF-UCL.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   SORL_HUMAN              Reviewed;        2214 AA.
AC   Q92673; B2RNX7; Q92856;
DE   RecName: Full=Sortilin-related receptor;
DE   AltName: Full=Low-density lipoprotein receptor relative with 11 ligand-binding repeats;
DE            Short=LDLR relative with 11 ligand-binding repeats;
DE            Short=LR11;
DE   AltName: Full=SorLA-1;
DE   AltName: Full=Sorting protein-related receptor containing LDLR class A repeats;
DE            Short=SorLA;
DE   Flags: Precursor;
GN   Name=SORL1; Synonyms=C11orf32;
DR   GO; GO:0030306; F:ADP-ribosylation factor binding; IPI:Alzheimers_University_of_Toronto.
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0042987; P:amyloid precursor protein catabolic process; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0061502; P:early endosome to recycling endosome transport; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:1902430; P:negative regulation of beta-amyloid formation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0032460; P:negative regulation of protein oligomerization; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:2001137; P:positive regulation of endocytic recycling; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0070863; P:positive regulation of protein exit from endoplasmic reticulum; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0036010; P:protein localization to endosome; IMP:Alzheimers_University_of_Toronto.
DR   GO; GO:0051604; P:protein maturation; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0045053; P:protein retention in Golgi apparatus; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006605; P:protein targeting; IMP:UniProtKB.
DR   GO; GO:0000042; P:protein targeting to Golgi; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006622; P:protein targeting to lysosome; IDA:Alzheimers_University_of_Toronto.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
DR   GO; GO:0014910; P:regulation of smooth muscle cell migration; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   SORT_HUMAN              Reviewed;         831 AA.
AC   Q99523; B4DWI3; C0JYZ0; Q8IZ49;
DE   RecName: Full=Sortilin;
DE   AltName: Full=100 kDa NT receptor;
DE   AltName: Full=Glycoprotein 95;
DE            Short=Gp95;
DE   AltName: Full=Neurotensin receptor 3;
DE            Short=NT3;
DE            Short=NTR3;
DE   Flags: Precursor;
GN   Name=SORT1;
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0048406; F:nerve growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0010465; F:nerve growth factor receptor activity; IDA:BHF-UCL.
DR   GO; GO:0030379; F:neurotensin receptor activity, non-G-protein coupled; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006897; P:endocytosis; IDA:BHF-UCL.
DR   GO; GO:0008333; P:endosome to lysosome transport; IDA:BHF-UCL.
DR   GO; GO:0032509; P:endosome transport via multivesicular body sorting pathway; IDA:BHF-UCL.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0046323; P:glucose import; IMP:BHF-UCL.
DR   GO; GO:0006895; P:Golgi to endosome transport; IDA:BHF-UCL.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0014902; P:myotube differentiation; IMP:BHF-UCL.
DR   GO; GO:0051005; P:negative regulation of lipoprotein lipase activity; IDA:BHF-UCL.
DR   GO; GO:0038180; P:nerve growth factor signaling pathway; IDA:GOC.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0048227; P:plasma membrane to endosome transport; IDA:BHF-UCL.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0032868; P:response to insulin; IMP:BHF-UCL.
DR   GO; GO:0016050; P:vesicle organization; IDA:BHF-UCL.
//
ID   SOS1_HUMAN              Reviewed;        1333 AA.
AC   Q07889; A8K2G3;
DE   RecName: Full=Son of sevenless homolog 1;
DE            Short=SOS-1;
GN   Name=SOS1;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; EXP:Reactome.
DR   GO; GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0032318; P:regulation of Ras GTPase activity; EXP:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   SOS2_HUMAN              Reviewed;        1332 AA.
AC   Q07890; B7ZKT6; D3DSB4; Q15503; Q17RN1;
DE   RecName: Full=Son of sevenless homolog 2;
DE            Short=SOS-2;
GN   Name=SOS2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   SOSB1_HUMAN             Reviewed;         211 AA.
AC   Q9BQ15; A6NDF8; Q6XYC8;
DE   RecName: Full=SOSS complex subunit B1;
DE   AltName: Full=Nucleic acid-binding protein 2;
DE   AltName: Full=Oligonucleotide/oligosaccharide-binding fold-containing protein 2B;
DE   AltName: Full=Sensor of single-strand DNA complex subunit B1;
DE   AltName: Full=Sensor of ssDNA subunit B1;
DE            Short=SOSS-B1;
DE   AltName: Full=Single-stranded DNA-binding protein 1;
DE            Short=hSSB1;
GN   Name=NABP2; Synonyms=OBFC2B, SSB1; ORFNames=LP3587;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
//
ID   SOSB2_HUMAN             Reviewed;         204 AA.
AC   Q96AH0; Q658Y8; Q9H5X6;
DE   RecName: Full=SOSS complex subunit B2;
DE   AltName: Full=Nucleic acid-binding protein 1;
DE   AltName: Full=Oligonucleotide/oligosaccharide-binding fold-containing protein 2A;
DE   AltName: Full=Sensor of single-strand DNA complex subunit B2;
DE   AltName: Full=Sensor of ssDNA subunit B2;
DE            Short=SOSS-B2;
DE   AltName: Full=Single-stranded DNA-binding protein 2;
DE            Short=hSSB2;
GN   Name=NABP1; Synonyms=OBFC2A, SSB2;
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
//
ID   SOSD1_HUMAN             Reviewed;         206 AA.
AC   Q6X4U4; A8MUA6; Q96HJ7; Q9Y3U3;
DE   RecName: Full=Sclerostin domain-containing protein 1;
DE   AltName: Full=Ectodermal BMP inhibitor;
DE            Short=Ectodin;
DE   AltName: Full=Uterine sensitization-associated gene 1 protein;
DE            Short=USAG-1;
DE   Flags: Precursor;
GN   Name=SOSTDC1; Synonyms=USAG1; ORFNames=CDA019;
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0060648; P:mammary gland bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0010454; P:negative regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   SOSSC_HUMAN             Reviewed;         104 AA.
AC   Q9NRY2; Q5VWJ7; Q96E04; Q9P090;
DE   RecName: Full=SOSS complex subunit C;
DE   AltName: Full=INTS3- and NABP-interacting protein;
DE   AltName: Full=Sensor of single-strand DNA complex subunit C;
DE   AltName: Full=Sensor of ssDNA subunit C;
DE            Short=SOSS-C;
DE   AltName: Full=Single-stranded DNA-binding protein-interacting protein 1;
DE            Short=SSB-interacting protein 1;
DE            Short=hSSBIP1;
GN   Name=INIP; Synonyms=C9orf80, SSBIP1; ORFNames=HSPC043, HSPC291;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
//
ID   SOST_HUMAN              Reviewed;         213 AA.
AC   Q9BQB4; Q495N9;
DE   RecName: Full=Sclerostin;
DE   Flags: Precursor;
GN   Name=SOST; ORFNames=UNQ2976/PRO7455/PRO7476;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0071374; P:cellular response to parathyroid hormone stimulus; IDA:UniProtKB.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:MGI.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0030279; P:negative regulation of ossification; NAS:UniProtKB.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:2000054; P:negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; IDA:BHF-UCL.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   SOX10_HUMAN             Reviewed;         466 AA.
AC   P56693; B4DV62; Q6FHW7;
DE   RecName: Full=Transcription factor SOX-10;
GN   Name=SOX10;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0014015; P:positive regulation of gliogenesis; IEA:Ensembl.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   SOX11_HUMAN             Reviewed;         441 AA.
AC   P35716; Q4ZFV8;
DE   RecName: Full=Transcription factor SOX-11;
GN   Name=SOX11;
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001071; F:nucleic acid binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; IDA:UniProtKB.
DR   GO; GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.
DR   GO; GO:0061386; P:closure of optic fissure; ISS:UniProtKB.
DR   GO; GO:0061303; P:cornea development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0021782; P:glial cell development; ISS:UniProtKB.
DR   GO; GO:0014009; P:glial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060022; P:hard palate development; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0060174; P:limb bud formation; ISS:UniProtKB.
DR   GO; GO:0060425; P:lung morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0060253; P:negative regulation of glial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050672; P:negative regulation of lymphocyte proliferation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0014032; P:neural crest cell development; ISS:UniProtKB.
DR   GO; GO:0001841; P:neural tube formation; ISS:UniProtKB.
DR   GO; GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; IEP:UniProtKB.
DR   GO; GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0035332; P:positive regulation of hippo signaling; ISS:UniProtKB.
DR   GO; GO:0046887; P:positive regulation of hormone secretion; ISS:UniProtKB.
DR   GO; GO:2001111; P:positive regulation of lens epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:UniProtKB.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IMP:UniProtKB.
DR   GO; GO:0045778; P:positive regulation of ossification; IMP:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IEP:UniProtKB.
DR   GO; GO:0072395; P:signal transduction involved in cell cycle checkpoint; IEP:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; ISS:UniProtKB.
DR   GO; GO:0060023; P:soft palate development; ISS:UniProtKB.
DR   GO; GO:0061053; P:somite development; ISS:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; ISS:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; IDA:GOC.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:UniProtKB.
//
ID   SOX13_HUMAN             Reviewed;         622 AA.
AC   Q9UN79; B4E2B0; O95275; O95826; Q3KQV7; Q5SXX1; Q9UHW7;
DE   RecName: Full=Transcription factor SOX-13;
DE   AltName: Full=Islet cell antigen 12;
DE   AltName: Full=SRY (Sex determining region Y)-box 13;
DE   AltName: Full=Type 1 diabetes autoantigen ICA12;
GN   Name=SOX13;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOX14_HUMAN             Reviewed;         240 AA.
AC   O95416; B2RAC0; Q3KPH7;
DE   RecName: Full=Transcription factor SOX-14;
DE   AltName: Full=Protein SOX-28;
GN   Name=SOX14; Synonyms=SOX28;
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOX15_HUMAN             Reviewed;         233 AA.
AC   O60248; D3DTQ0; P35717; Q9Y6W7;
DE   RecName: Full=Protein SOX-15;
DE   AltName: Full=Protein SOX-12;
DE   AltName: Full=Protein SOX-20;
GN   Name=SOX15; Synonyms=SOX12, SOX20, SOX26, SOX27;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0048627; P:myoblast development; ISS:BHF-UCL.
DR   GO; GO:0045843; P:negative regulation of striated muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0070318; P:positive regulation of G0 to G1 transition; ISS:BHF-UCL.
DR   GO; GO:2000288; P:positive regulation of myoblast proliferation; ISS:BHF-UCL.
DR   GO; GO:0014718; P:positive regulation of satellite cell activation involved in skeletal muscle regeneration; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0043403; P:skeletal muscle tissue regeneration; IEA:Ensembl.
//
ID   SOX12_HUMAN             Reviewed;         315 AA.
AC   O15370; Q5D038; Q9NUD4;
DE   RecName: Full=Transcription factor SOX-12;
DE   AltName: Full=Protein SOX-22;
GN   Name=SOX12; Synonyms=SOX22;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0065004; P:protein-DNA complex assembly; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; ISS:UniProtKB.
//
ID   SOX17_HUMAN             Reviewed;         414 AA.
AC   Q9H6I2;
DE   RecName: Full=Transcription factor SOX-17;
GN   Name=SOX17;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060913; P:cardiac cell fate determination; IMP:BHF-UCL.
DR   GO; GO:0003142; P:cardiogenic plate morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042074; P:cell migration involved in gastrulation; IEA:Ensembl.
DR   GO; GO:0061009; P:common bile duct development; IEA:Ensembl.
DR   GO; GO:0048617; P:embryonic foregut morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035050; P:embryonic heart tube development; ISS:BHF-UCL.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060956; P:endocardial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060214; P:endocardium formation; ISS:BHF-UCL.
DR   GO; GO:0001706; P:endoderm formation; IDA:UniProtKB.
DR   GO; GO:0007493; P:endodermal cell fate determination; IEA:Ensembl.
DR   GO; GO:0061031; P:endodermal digestive tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0061010; P:gall bladder development; IEA:Ensembl.
DR   GO; GO:0060914; P:heart formation; TAS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:UniProtKB.
DR   GO; GO:0001828; P:inner cell mass cellular morphogenesis; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.
DR   GO; GO:0042662; P:negative regulation of mesodermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0003308; P:negative regulation of Wnt signaling pathway involved in heart development; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0031648; P:protein destabilization; IMP:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IMP:BHF-UCL.
DR   GO; GO:2000043; P:regulation of cardiac cell fate specification; IEA:Ensembl.
DR   GO; GO:0045995; P:regulation of embryonic development; ISS:UniProtKB.
DR   GO; GO:2000035; P:regulation of stem cell division; IEA:Ensembl.
DR   GO; GO:0072091; P:regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0060807; P:regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification; ISS:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0072001; P:renal system development; IMP:BHF-UCL.
DR   GO; GO:0021903; P:rostrocaudal neural tube patterning; IEA:Ensembl.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0048866; P:stem cell fate specification; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
//
ID   SOX18_HUMAN             Reviewed;         384 AA.
AC   P35713; Q0VGA9; Q9NPH8;
DE   RecName: Full=Transcription factor SOX-18;
GN   Name=SOX18;
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEP:UniProtKB.
DR   GO; GO:0043534; P:blood vessel endothelial cell migration; IEP:UniProtKB.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0035050; P:embryonic heart tube development; ISS:BHF-UCL.
DR   GO; GO:0060956; P:endocardial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060214; P:endocardium formation; ISS:BHF-UCL.
DR   GO; GO:0061028; P:establishment of endothelial barrier; IMP:UniProtKB.
DR   GO; GO:0022405; P:hair cycle process; IMP:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
DR   GO; GO:0060836; P:lymphatic endothelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0072091; P:regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0048866; P:stem cell fate specification; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; ISS:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
//
ID   SOX1_HUMAN              Reviewed;         391 AA.
AC   O00570; Q5W0Q1;
DE   RecName: Full=Transcription factor SOX-1;
GN   Name=SOX1;
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0021884; P:forebrain neuron development; IEA:Ensembl.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021521; P:ventral spinal cord interneuron specification; IEA:Ensembl.
//
ID   SOX21_HUMAN             Reviewed;         276 AA.
AC   Q9Y651; P35715; Q15504; Q5TBS1;
DE   RecName: Full=Transcription factor SOX-21;
DE   AltName: Full=SOX-A;
GN   Name=SOX21; Synonyms=SOX25, SOXA;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; NAS:GOC.
//
ID   SOX2_HUMAN              Reviewed;         317 AA.
AC   P48431; Q14537;
DE   RecName: Full=Transcription factor SOX-2;
GN   Name=SOX2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0035198; F:miRNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0021984; P:adenohypophysis development; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0050973; P:detection of mechanical stimulus involved in equilibrioception; IEA:Ensembl.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0048852; P:diencephalon morphogenesis; IEA:Ensembl.
DR   GO; GO:0001714; P:endodermal cell fate specification; IDA:MGI.
DR   GO; GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0001654; P:eye development; IEP:UniProtKB.
DR   GO; GO:0030900; P:forebrain development; IEP:UniProtKB.
DR   GO; GO:0021879; P:forebrain neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021781; P:glial cell fate commitment; NAS:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; IEP:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0030910; P:olfactory placode formation; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0046148; P:pigment biosynthetic process; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEP:UniProtKB.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0070848; P:response to growth factor; IDA:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEP:UniProtKB.
DR   GO; GO:0060042; P:retina morphogenesis in camera-type eye; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IDA:UniProtKB.
DR   GO; GO:0043586; P:tongue development; IEA:Ensembl.
//
ID   SOX30_HUMAN             Reviewed;         753 AA.
AC   O94993; O94995; Q8IYX6;
DE   RecName: Full=Transcription factor SOX-30;
GN   Name=SOX30;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0031960; P:response to corticosteroid; IEP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOX3_HUMAN              Reviewed;         446 AA.
AC   P41225; P35714; Q5JWI3; Q9NP49;
DE   RecName: Full=Transcription factor SOX-3;
GN   Name=SOX3;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0060324; P:face development; ISS:UniProtKB.
DR   GO; GO:0021854; P:hypothalamus development; ISS:UniProtKB.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; ISS:UniProtKB.
DR   GO; GO:0007423; P:sensory organ development; ISS:UniProtKB.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0007530; P:sex determination; IMP:UniProtKB.
DR   GO; GO:0048515; P:spermatid differentiation; IEA:Ensembl.
//
ID   SOX5_HUMAN              Reviewed;         763 AA.
AC   P35711; B7Z8V0; F5H5B0; Q86UK8; Q8J017; Q8J018; Q8J019; Q8J020;
AC   Q8N1D9; Q8N7E0; Q8TEA4;
DE   RecName: Full=Transcription factor SOX-5;
GN   Name=SOX5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060164; P:regulation of timing of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   SOX6_HUMAN              Reviewed;         828 AA.
AC   P35712; Q86VX7; Q9BXQ3; Q9BXQ4; Q9BXQ5; Q9H0I8;
DE   RecName: Full=Transcription factor SOX-6;
GN   Name=SOX6;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0048708; P:astrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0035051; P:cardiocyte differentiation; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0016458; P:gene silencing; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042692; P:muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021778; P:oligodendrocyte cell fate specification; IEA:Ensembl.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOX4_HUMAN              Reviewed;         474 AA.
AC   Q06945;
DE   RecName: Full=Transcription factor SOX-4;
GN   Name=SOX4;
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001071; F:nucleic acid binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0035910; P:ascending aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003289; P:atrial septum primum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003211; P:cardiac ventricle formation; ISS:UniProtKB.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; ISS:UniProtKB.
DR   GO; GO:0042769; P:DNA damage response, detection of DNA damage; IDA:UniProtKB.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0021782; P:glial cell development; ISS:UniProtKB.
DR   GO; GO:0014009; P:glial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0060993; P:kidney morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060174; P:limb bud formation; ISS:UniProtKB.
DR   GO; GO:0003183; P:mitral valve morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0046826; P:negative regulation of protein export from nucleus; IMP:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0001841; P:neural tube formation; ISS:UniProtKB.
DR   GO; GO:0060563; P:neuroepithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0003357; P:noradrenergic neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:2000761; P:positive regulation of N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IMP:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0002328; P:pro-B cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IMP:BHF-UCL.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0001501; P:skeletal system development; ISS:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0021510; P:spinal cord development; ISS:UniProtKB.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0048485; P:sympathetic nervous system development; ISS:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; ISS:BHF-UCL.
//
ID   SOX7_HUMAN              Reviewed;         388 AA.
AC   Q9BT81; Q53YD0;
DE   RecName: Full=Transcription factor SOX-7;
GN   Name=SOX7;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001706; P:endoderm formation; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SOX8_HUMAN              Reviewed;         446 AA.
AC   P57073; Q9NZW2;
DE   RecName: Full=Transcription factor SOX-8;
GN   Name=SOX8;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0060612; P:adipose tissue development; ISS:UniProtKB.
DR   GO; GO:0060018; P:astrocyte fate commitment; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0048484; P:enteric nervous system development; ISS:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; ISS:UniProtKB.
DR   GO; GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.
DR   GO; GO:0061138; P:morphogenesis of a branching epithelium; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0046533; P:negative regulation of photoreceptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0007422; P:peripheral nervous system development; ISS:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0014015; P:positive regulation of gliogenesis; ISS:UniProtKB.
DR   GO; GO:0090184; P:positive regulation of kidney development; ISS:UniProtKB.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0010817; P:regulation of hormone levels; ISS:UniProtKB.
DR   GO; GO:0072034; P:renal vesicle induction; ISS:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.
DR   GO; GO:0060009; P:Sertoli cell development; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0072197; P:ureter morphogenesis; ISS:UniProtKB.
//
ID   SOX9_HUMAN              Reviewed;         509 AA.
AC   P48436; Q53Y80;
DE   RecName: Full=Transcription factor SOX-9;
GN   Name=SOX9;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0035326; F:enhancer binding; IDA:UniProtKB.
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0060018; P:astrocyte fate commitment; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0019933; P:cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0001502; P:cartilage condensation; ISS:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; ISS:UniProtKB.
DR   GO; GO:0001708; P:cell fate specification; ISS:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0071504; P:cellular response to heparin; ISS:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IEP:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:UniProtKB.
DR   GO; GO:0003413; P:chondrocyte differentiation involved in endochondral bone morphogenesis; IMP:UniProtKB.
DR   GO; GO:0003415; P:chondrocyte hypertrophy; ISS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:UniProtKB.
DR   GO; GO:0031018; P:endocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060517; P:epithelial cell proliferation involved in prostatic bud elongation; ISS:UniProtKB.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; ISS:UniProtKB.
DR   GO; GO:0003170; P:heart valve development; ISS:UniProtKB.
DR   GO; GO:0003188; P:heart valve formation; IEA:Ensembl.
DR   GO; GO:0003179; P:heart valve morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060729; P:intestinal epithelial structure maintenance; ISS:UniProtKB.
DR   GO; GO:0035622; P:intrahepatic bile duct development; IEA:Ensembl.
DR   GO; GO:0060174; P:limb bud formation; IEA:Ensembl.
DR   GO; GO:0019100; P:male germ-line sex determination; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IMP:UniProtKB.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.
DR   GO; GO:0061138; P:morphogenesis of a branching epithelium; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0070168; P:negative regulation of biomineral tissue development; ISS:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0002683; P:negative regulation of immune system process; ISS:UniProtKB.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0030279; P:negative regulation of ossification; ISS:UniProtKB.
DR   GO; GO:0046533; P:negative regulation of photoreceptor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0014032; P:neural crest cell development; IEA:Ensembl.
DR   GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR   GO; GO:0006334; P:nucleosome assembly; IDA:UniProtKB.
DR   GO; GO:0048709; P:oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0030916; P:otic vesicle formation; ISS:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IMP:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEP:UniProtKB.
DR   GO; GO:0090184; P:positive regulation of kidney development; ISS:UniProtKB.
DR   GO; GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:2000741; P:positive regulation of mesenchymal stem cell differentiation; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030850; P:prostate gland development; IEP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0010564; P:regulation of cell cycle process; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0060784; P:regulation of cell proliferation involved in tissue homeostasis; ISS:UniProtKB.
DR   GO; GO:0072034; P:renal vesicle induction; ISS:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; ISS:UniProtKB.
DR   GO; GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.
DR   GO; GO:0060009; P:Sertoli cell development; IEA:Ensembl.
DR   GO; GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; ISS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0001894; P:tissue homeostasis; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0072197; P:ureter morphogenesis; IEA:Ensembl.
DR   GO; GO:0072190; P:ureter urothelium development; IEA:Ensembl.
//
ID   SOX_HUMAN               Reviewed;         390 AA.
AC   Q9P0Z9; B3KNH0; Q96H28; Q9C070;
DE   RecName: Full=Peroxisomal sarcosine oxidase;
DE            Short=PSO;
DE            EC=1.5.3.1;
DE            EC=1.5.3.7;
DE   AltName: Full=L-pipecolate oxidase;
DE   AltName: Full=L-pipecolic acid oxidase;
GN   Name=PIPOX; Synonyms=LPIPOX, PSO;
DR   GO; GO:0050031; F:L-pipecolate oxidase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0033514; P:L-lysine catabolic process to acetyl-CoA via L-pipecolate; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
//
ID   SP100_HUMAN             Reviewed;         879 AA.
AC   P23497; B4DDX5; B8ZZD8; E7EUA7; E9PH61; F8WFE2; O75450; Q13343;
AC   Q8TE34; Q96F70; Q96T24; Q96T95; Q9NP33; Q9UE32;
DE   RecName: Full=Nuclear autoantigen Sp-100;
DE   AltName: Full=Nuclear dot-associated Sp100 protein;
DE   AltName: Full=Speckled 100 kDa;
GN   Name=SP100;
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:BHF-UCL.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; IC:BHF-UCL.
DR   GO; GO:0051271; P:negative regulation of cellular component movement; IMP:BHF-UCL.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0046826; P:negative regulation of protein export from nucleus; IMP:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045765; P:regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:1902041; P:regulation of extrinsic apoptotic signaling pathway via death domain receptors; IMP:UniProtKB.
DR   GO; GO:1902044; P:regulation of Fas signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IDA:BHF-UCL.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
DR   GO; GO:0034340; P:response to type I interferon; IDA:BHF-UCL.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; IC:BHF-UCL.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; IC:BHF-UCL.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SP110_HUMAN             Reviewed;         689 AA.
AC   Q9HB58; B4DVI4; F5H1M1; Q14976; Q14977; Q53TG2; Q8WUZ6; Q9HCT8;
DE   RecName: Full=Sp110 nuclear body protein;
DE   AltName: Full=Interferon-induced protein 41/75;
DE   AltName: Full=Speckled 110 kDa;
DE   AltName: Full=Transcriptional coactivator Sp110;
GN   Name=SP110;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SP130_HUMAN             Reviewed;        1048 AA.
AC   Q9H0E3; B7ZLM3; C9K0X9; Q4ZFV4; Q53T46; Q8WVW4; Q9H9G8;
DE   RecName: Full=Histone deacetylase complex subunit SAP130;
DE   AltName: Full=130 kDa Sin3-associated polypeptide;
DE   AltName: Full=Sin3-associated polypeptide p130;
GN   Name=SAP130;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP140_HUMAN             Reviewed;         867 AA.
AC   Q13342; Q13341; Q4ZG66; Q53TG1; Q6NSG4; Q92881; Q96TG3;
DE   RecName: Full=Nuclear body protein SP140;
DE   AltName: Full=Lymphoid-restricted homolog of Sp100;
DE            Short=LYSp100;
DE   AltName: Full=Nuclear autoantigen Sp-140;
DE   AltName: Full=Speckled 140 kDa;
GN   Name=SP140; Synonyms=LYSP100;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
//
ID   SP14L_HUMAN             Reviewed;         580 AA.
AC   Q9H930; Q2M375; Q4ZG65; Q9BSP3;
DE   RecName: Full=Nuclear body protein SP140-like protein;
GN   Name=SP140L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   SP16H_HUMAN             Reviewed;        1047 AA.
AC   Q9Y5B9; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0;
DE   RecName: Full=FACT complex subunit SPT16;
DE   AltName: Full=Chromatin-specific transcription elongation factor 140 kDa subunit;
DE   AltName: Full=FACT 140 kDa subunit;
DE   AltName: Full=FACTp140;
DE   AltName: Full=Facilitates chromatin transcription complex subunit SPT16;
DE            Short=hSPT16;
GN   Name=SUPT16H; Synonyms=FACT140, FACTP140;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006337; P:nucleosome disassembly; TAS:ProtInc.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; TAS:ProtInc.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   SP17_HUMAN              Reviewed;         151 AA.
AC   Q15506; B2R4F2; Q9BXF7;
DE   RecName: Full=Sperm surface protein Sp17;
DE   AltName: Full=Cancer/testis antigen 22;
DE            Short=CT22;
DE   AltName: Full=Sp17-1;
DE   AltName: Full=Sperm autoantigenic protein 17;
DE            Short=Sperm protein 17;
GN   Name=SPA17; Synonyms=SP17;
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
DR   GO; GO:0003351; P:epithelial cilium movement; NAS:BHF-UCL.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   SP1_HUMAN               Reviewed;         785 AA.
AC   P08047; E4Z9M7; G5E9M8; Q86TN8; Q9H3Q5; Q9NR51; Q9NY21; Q9NYE7;
DE   RecName: Full=Transcription factor Sp1;
GN   Name=SP1; Synonyms=TSFP1;
DR   GO; GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.
DR   GO; GO:0035326; F:enhancer binding; IEA:Ensembl.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0071837; F:HMG box domain binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:HGNC.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0030219; P:megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SP20H_HUMAN             Reviewed;         779 AA.
AC   Q8NEM7; Q71RF3; Q9Y6A6;
DE   RecName: Full=Transcription factor SPT20 homolog;
DE   AltName: Full=p38-interacting protein;
DE            Short=p38IP;
GN   Name=SUPT20H; Synonyms=C13orf19, FAM48A; ORFNames=FP757;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003712; F:transcription cofactor activity; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0007369; P:gastrulation; IEA:UniProtKB-KW.
//
ID   SP201_HUMAN             Reviewed;         823 AA.
AC   Q3ZLR7;
DE   RecName: Full=Transcription factor SPT20 homolog-like 1;
GN   Name=SUPT20HL1; Synonyms=FAM48B1;
DR   GO; GO:0003712; F:transcription cofactor activity; IEA:InterPro.
//
ID   SP202_HUMAN             Reviewed;         817 AA.
AC   P0C7V6;
DE   RecName: Full=Putative transcription factor SPT20 homolog-like 2;
GN   Name=SUPT20HL2; Synonyms=FAM48B2;
DR   GO; GO:0003712; F:transcription cofactor activity; IEA:InterPro.
//
ID   SP2_HUMAN               Reviewed;         613 AA.
AC   Q02086; A6NK74;
DE   RecName: Full=Transcription factor Sp2;
GN   Name=SP2; Synonyms=KIAA0048;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0072358; P:cardiovascular system development; IEA:Ensembl.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0048144; P:fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP30L_HUMAN             Reviewed;         183 AA.
AC   Q9HAJ7; E9PAU7; E9PAY2;
DE   RecName: Full=Histone deacetylase complex subunit SAP30L;
DE   AltName: Full=HCV non-structural protein 4A-transactivated protein 2;
DE   AltName: Full=Sin3 corepressor complex subunit SAP30L;
DE   AltName: Full=Sin3-associated protein p30-like;
GN   Name=SAP30L; Synonyms=NS4ATP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP3_HUMAN               Reviewed;         781 AA.
AC   Q02447; A0AVL9; B4E2B7; Q69B26; Q69B27; Q8TD56; Q8WWU4; Q9BQR1;
DE   RecName: Full=Transcription factor Sp3;
DE   AltName: Full=SPR-2;
GN   Name=SP3;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0060136; P:embryonic process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030851; P:granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0030219; P:megakaryocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030224; P:monocyte differentiation; IEA:Ensembl.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IEA:Ensembl.
//
ID   SP4_HUMAN               Reviewed;         784 AA.
AC   Q02446; O60402; Q32M52;
DE   RecName: Full=Transcription factor Sp4;
DE   AltName: Full=SPR-1;
GN   Name=SP4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP5_HUMAN               Reviewed;         398 AA.
AC   Q6BEB4;
DE   RecName: Full=Transcription factor Sp5;
GN   Name=SP5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0060349; P:bone morphogenesis; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP6_HUMAN               Reviewed;         376 AA.
AC   Q3SY56; B3KXS4;
DE   RecName: Full=Transcription factor Sp6;
DE   AltName: Full=Krueppel-like factor 14;
GN   Name=SP6; Synonyms=KLF14;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042481; P:regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP7_HUMAN               Reviewed;         431 AA.
AC   Q8TDD2; B3KY26; Q3MJ72; Q7Z718;
DE   RecName: Full=Transcription factor Sp7;
DE   AltName: Full=Zinc finger protein osterix;
GN   Name=SP7; Synonyms=OSX;
DR   GO; GO:0017151; F:DEAD/H-box RNA helicase binding; ISS:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; ISS:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:2000738; P:positive regulation of stem cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP8_HUMAN               Reviewed;         490 AA.
AC   Q8IXZ3; Q7Z615; Q7Z616; Q96MJ1;
DE   RecName: Full=Transcription factor Sp8;
DE   AltName: Full=Specificity protein 8;
GN   Name=SP8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0009954; P:proximal/distal pattern formation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SP9_HUMAN               Reviewed;         484 AA.
AC   P0CG40;
DE   RecName: Full=Transcription factor Sp9;
GN   Name=SP9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SPA11_HUMAN             Reviewed;         422 AA.
AC   Q86U17; B2RV07;
DE   RecName: Full=Serpin A11;
DE   Flags: Precursor;
GN   Name=SERPINA11;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPA12_HUMAN             Reviewed;         414 AA.
AC   Q8IW75;
DE   RecName: Full=Serpin A12;
DE   AltName: Full=OL-64;
DE   AltName: Full=Visceral adipose tissue-derived serine protease inhibitor;
DE            Short=Vaspin;
DE   AltName: Full=Visceral adipose-specific serpin;
DE   Flags: Precursor;
GN   Name=SERPINA12;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPA13_HUMAN             Reviewed;         307 AA.
AC   Q6UXR4;
DE   RecName: Full=Putative serpin A13;
DE   Flags: Precursor;
GN   Name=SERPINA13P; Synonyms=SERPINA13; ORFNames=UNQ6121/PRO20043;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPA24_HUMAN             Reviewed;         205 AA.
AC   Q86W54;
DE   RecName: Full=Spermatogenesis-associated protein 24;
DE   AltName: Full=Testis protein T6441 homolog;
GN   Name=SPATA24;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SPA2L_HUMAN             Reviewed;         424 AA.
AC   Q8IUW3; D3DX85; Q8NHV3;
DE   RecName: Full=Spermatogenesis-associated protein 2-like protein;
DE            Short=SPATA2-like protein;
GN   Name=SPATA2L; Synonyms=C16orf76;
//
ID   SPA5L_HUMAN             Reviewed;         753 AA.
AC   Q9BVQ7; C9JHR5; Q9H8W7; Q9HA41;
DE   RecName: Full=Spermatogenesis-associated protein 5-like protein 1;
GN   Name=SPATA5L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
//
ID   SPA9_HUMAN              Reviewed;         417 AA.
AC   Q86WD7; B4DVH4; B9ZVX3; Q2T9J2; Q6UWP9; Q86WD4; Q86WD5; Q86WD6;
AC   Q86YP6; Q86YP7;
DE   RecName: Full=Serpin A9;
DE   AltName: Full=Centerin;
DE   AltName: Full=Germinal center B-cell-expressed transcript 1 protein;
DE   Flags: Precursor;
GN   Name=SERPINA9; Synonyms=GCET1, SERPINA11; ORFNames=UNQ692/PRO1337;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPA6L_HUMAN             Reviewed;         392 AA.
AC   Q8N4H0; B4DIY4; Q5JVJ5; Q8IY90;
DE   RecName: Full=Spermatogenesis associated 6-like protein;
GN   Name=SPATA6L; Synonyms=C9orf68;
//
ID   SPAC7_HUMAN             Reviewed;         195 AA.
AC   Q96KW9; Q5T8L1;
DE   RecName: Full=Protein SPACA7;
DE   AltName: Full=Sperm acrosome-associated protein 7;
DE   Flags: Precursor;
GN   Name=SPACA7; Synonyms=C13orf28;
//
ID   SPAG1_HUMAN             Reviewed;         926 AA.
AC   Q07617; A6NP70; B3KQ58; G3XAM3; Q7Z5G1;
DE   RecName: Full=Sperm-associated antigen 1;
DE   AltName: Full=HSD-3.8;
DE   AltName: Full=Infertility-related sperm protein Spag-1;
GN   Name=SPAG1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0070286; P:axonemal dynein complex assembly; ISS:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   SPAG4_HUMAN             Reviewed;         437 AA.
AC   Q9NPE6; O43648;
DE   RecName: Full=Sperm-associated antigen 4 protein;
DE   AltName: Full=Outer dense fiber-associated protein SPAG4;
DE   AltName: Full=SUN domain-containing protein 4;
GN   Name=SPAG4; Synonyms=SUN4;
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   SPAG5_HUMAN             Reviewed;        1193 AA.
AC   Q96R06; O95213; Q9BWE8; Q9NT17; Q9UFE6;
DE   RecName: Full=Sperm-associated antigen 5;
DE   AltName: Full=Astrin;
DE   AltName: Full=Deepest;
DE   AltName: Full=Mitotic spindle-associated protein p126;
DE            Short=MAP126;
GN   Name=SPAG5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; IMP:UniProtKB.
//
ID   SPAG6_HUMAN             Reviewed;         509 AA.
AC   O75602; A8K1I8; B4DXZ4; Q5VUX5; Q5VUX6; Q5VUX7; Q6FI74; Q8NHQ6;
DE   RecName: Full=Sperm-associated antigen 6;
DE   AltName: Full=Protein PF16 homolog;
DE   AltName: Full=Repro-SA-1;
DE   AltName: Full=Sperm flagellar protein;
GN   Name=SPAG6; Synonyms=PF16;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; TAS:ProtInc.
//
ID   SPAG7_HUMAN             Reviewed;         227 AA.
AC   O75391; Q96EU5;
DE   RecName: Full=Sperm-associated antigen 7;
GN   Name=SPAG7;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   SPAG8_HUMAN             Reviewed;         426 AA.
AC   Q99932; B4DY89; E9PDV6; Q12937; Q5TCV8; Q8WWB4;
DE   RecName: Full=Sperm-associated antigen 8;
DE   AltName: Full=HSD-1;
DE   AltName: Full=Sperm membrane protein 1;
DE            Short=SMP-1;
DE   AltName: Full=Sperm membrane protein BS-84;
GN   Name=SPAG8;
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   SPAS1_HUMAN             Reviewed;         300 AA.
AC   Q496A3; Q496A2; Q496A5; Q96LJ0;
DE   RecName: Full=Spermatogenesis-associated serine-rich protein 1;
GN   Name=SPATS1;
//
ID   SPAS2_HUMAN             Reviewed;         545 AA.
AC   Q86XZ4; A8K8G9; Q9H7D4; Q9H8Y7; Q9H8Z8;
DE   RecName: Full=Spermatogenesis-associated serine-rich protein 2;
DE   AltName: Full=Serine-rich spermatocytes and round spermatid 59 kDa protein;
DE   AltName: Full=p59scr;
GN   Name=SPATS2; Synonyms=SCR59, SPATA10; ORFNames=Nbla00526;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   SPAT1_HUMAN             Reviewed;         437 AA.
AC   Q5VX52; A0PJU9; Q0VDJ9; Q0VDK0; Q6P386; Q9HAR4;
DE   RecName: Full=Spermatogenesis-associated protein 1;
DE   AltName: Full=Sperm-specific protein SP-2;
GN   Name=SPATA1;
//
ID   SPAT4_HUMAN             Reviewed;         305 AA.
AC   Q8NEY3; Q8NCS5; Q8WW15;
DE   RecName: Full=Spermatogenesis-associated protein 4;
DE   AltName: Full=Testis and spermatogenesis cell-related protein 2;
DE   AltName: Full=Testis spermatocyte apoptosis-related gene 2 protein;
GN   Name=SPATA4; Synonyms=TSARG2;
//
ID   SPAST_HUMAN             Reviewed;         616 AA.
AC   Q9UBP0; A7E2A7; Q9UPR9;
DE   RecName: Full=Spastin;
DE            EC=3.6.4.3;
DE   AltName: Full=Spastic paraplegia 4 protein;
GN   Name=SPAST; Synonyms=ADPSP, FSP2, KIAA1083, SPG4;
DR   GO; GO:0043014; F:alpha-tubulin binding; IPI:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0048487; F:beta-tubulin binding; IPI:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0008568; F:microtubule-severing ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007409; P:axonogenesis; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007109; P:cytokinesis, completion of separation; IMP:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.
DR   GO; GO:0051013; P:microtubule severing; IDA:UniProtKB.
DR   GO; GO:0031117; P:positive regulation of microtubule depolymerization; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034214; P:protein hexamerization; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   SPAT5_HUMAN             Reviewed;         893 AA.
AC   Q8NB90; C9JT97; Q86XW1; Q8NI20; Q8TDL7;
DE   RecName: Full=Spermatogenesis-associated protein 5;
DE   AltName: Full=ATPase family protein 2 homolog;
DE   AltName: Full=Spermatogenesis-associated factor protein;
GN   Name=SPATA5; Synonyms=AFG2, SPAF;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPAT6_HUMAN             Reviewed;         488 AA.
AC   Q9NWH7; Q5T3N7; Q8WUE6;
DE   RecName: Full=Spermatogenesis-associated protein 6;
DE   Flags: Precursor;
GN   Name=SPATA6;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPAT7_HUMAN             Reviewed;         599 AA.
AC   Q9P0W8; Q5BKY5; Q8WX30; Q96HF3; Q9H0X0; Q9P0W7;
DE   RecName: Full=Spermatogenesis-associated protein 7;
DE   AltName: Full=HSD-3.1;
DE   AltName: Full=Spermatogenesis-associated protein HSD3;
GN   Name=SPATA7; Synonyms=HSD3;
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   SPAT2_HUMAN             Reviewed;         520 AA.
AC   Q9UM82; E1P626; O94857;
DE   RecName: Full=Spermatogenesis-associated protein 2;
DE   AltName: Full=Spermatogenesis-associated protein PD1;
GN   Name=SPATA2; Synonyms=KIAA0757, PD1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   SPAT9_HUMAN             Reviewed;         254 AA.
AC   Q9BWV2; A8K8H3; Q4G122; Q86X33; Q8NA28;
DE   RecName: Full=Spermatogenesis-associated protein 9;
DE   AltName: Full=Testis development protein NYD-SP16;
GN   Name=SPATA9;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPAT8_HUMAN             Reviewed;         105 AA.
AC   Q6RVD6; Q2KJ07;
DE   RecName: Full=Spermatogenesis-associated protein 8;
DE   AltName: Full=Spermatogenesis-related protein 8;
GN   Name=SPATA8;
//
ID   SPB10_HUMAN             Reviewed;         397 AA.
AC   P48595; Q4VAX4; Q4VAX7;
DE   RecName: Full=Serpin B10;
DE   AltName: Full=Bomapin;
DE   AltName: Full=Peptidase inhibitor 10;
DE            Short=PI-10;
GN   Name=SERPINB10; Synonyms=PI10;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB12_HUMAN             Reviewed;         405 AA.
AC   Q96P63;
DE   RecName: Full=Serpin B12;
GN   Name=SERPINB12;
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IMP:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB11_HUMAN             Reviewed;         392 AA.
AC   Q96P15; A8K9R0; Q5Q120; Q5Q121; Q5Q122; Q5Q123; Q6ISD3; Q96P13;
AC   Q96P14;
DE   RecName: Full=Serpin B11;
GN   Name=SERPINB11;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB13_HUMAN             Reviewed;         391 AA.
AC   Q9UIV8; A8K2Q8; Q3MII2; Q9HCX1; Q9UBW1; Q9UKG0;
DE   RecName: Full=Serpin B13;
DE   AltName: Full=HaCaT UV-repressible serpin;
DE            Short=Hurpin;
DE   AltName: Full=Headpin;
DE   AltName: Full=Peptidase inhibitor 13;
DE            Short=PI-13;
DE   AltName: Full=Proteinase inhibitor 13;
GN   Name=SERPINB13; Synonyms=PI13;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; NAS:UniProtKB.
DR   GO; GO:0009411; P:response to UV; TAS:ProtInc.
//
ID   SPB1_HUMAN              Reviewed;         847 AA.
AC   Q8IY81; B2RCA5; D3DU22; Q8N3A3; Q8WXX1; Q9BWM4; Q9NXT6;
DE   RecName: Full=pre-rRNA processing protein FTSJ3;
DE            EC=2.1.1.-;
DE   AltName: Full=2'-O-ribose RNA methyltransferase SPB1 homolog;
DE   AltName: Full=Protein ftsJ homolog 3;
DE   AltName: Full=Putative rRNA methyltransferase 3;
GN   Name=FTSJ3; ORFNames=SB92;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008649; F:rRNA methyltransferase activity; IEA:InterPro.
//
ID   SPB3_HUMAN              Reviewed;         390 AA.
AC   P29508; A6NDM2; B2RBT5; B3W5Y6; Q53H28; Q53YB5; Q86VF3; Q86W04;
AC   Q8IWL4; Q8IXI3; Q96J21; Q9BYF8;
DE   RecName: Full=Serpin B3;
DE   AltName: Full=Protein T4-A;
DE   AltName: Full=Squamous cell carcinoma antigen 1;
DE            Short=SCCA-1;
GN   Name=SERPINB3; Synonyms=SCCA, SCCA1;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IDA:UniProtKB.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:UniProtKB.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0009615; P:response to virus; IDA:GOC.
//
ID   SPB4_HUMAN              Reviewed;         390 AA.
AC   P48594; A8K847;
DE   RecName: Full=Serpin B4;
DE   AltName: Full=Leupin;
DE   AltName: Full=Peptidase inhibitor 11;
DE            Short=PI-11;
DE   AltName: Full=Squamous cell carcinoma antigen 2;
DE            Short=SCCA-2;
GN   Name=SERPINB4; Synonyms=PI11, SCCA2;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0010466; P:negative regulation of peptidase activity; IDA:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; NAS:UniProtKB.
//
ID   SPB5_HUMAN              Reviewed;         375 AA.
AC   P36952; B2R6Y4; Q6N0B4; Q8WW89;
DE   RecName: Full=Serpin B5;
DE   AltName: Full=Maspin;
DE   AltName: Full=Peptidase inhibitor 5;
DE            Short=PI-5;
GN   Name=SERPINB5; Synonyms=PI5;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0060512; P:prostate gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB6_HUMAN              Reviewed;         376 AA.
AC   P35237; B2RBA8; Q59F97; Q5TD06; Q7Z2Y7; Q96J44; Q9UDI7;
DE   RecName: Full=Serpin B6;
DE   AltName: Full=Cytoplasmic antiproteinase;
DE            Short=CAP;
DE   AltName: Full=Peptidase inhibitor 6;
DE            Short=PI-6;
DE   AltName: Full=Placental thrombin inhibitor;
GN   Name=SERPINB6; Synonyms=PI6, PTI;
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB7_HUMAN              Reviewed;         380 AA.
AC   O75635; B4DUW8; F5GZC0; Q1ED45; Q3KPG4;
DE   RecName: Full=Serpin B7;
DE   AltName: Full=Megsin;
DE   AltName: Full=TP55;
GN   Name=SERPINB7;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0072126; P:positive regulation of glomerular mesangial cell proliferation; IEA:Ensembl.
DR   GO; GO:0090362; P:positive regulation of platelet-derived growth factor production; IEA:Ensembl.
DR   GO; GO:0032914; P:positive regulation of transforming growth factor beta1 production; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB8_HUMAN              Reviewed;         374 AA.
AC   P50452; Q7Z2V6; Q8N178;
DE   RecName: Full=Serpin B8;
DE   AltName: Full=Cytoplasmic antiproteinase 2;
DE            Short=CAP-2;
DE            Short=CAP2;
DE   AltName: Full=Peptidase inhibitor 8;
DE            Short=PI-8;
GN   Name=SERPINB8; Synonyms=PI8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPB9_HUMAN              Reviewed;         376 AA.
AC   P50453; B2RBW3; Q5TD03;
DE   RecName: Full=Serpin B9;
DE   AltName: Full=Cytoplasmic antiproteinase 3;
DE            Short=CAP-3;
DE            Short=CAP3;
DE   AltName: Full=Peptidase inhibitor 9;
DE            Short=PI-9;
GN   Name=SERPINB9; Synonyms=PI9;
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; IEP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0002448; P:mast cell mediated immunity; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:GOC.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPC1L_HUMAN             Reviewed;         340 AA.
AC   Q9H0A9; B4E323; Q52LS9; Q6FIH5; Q6P0L3; Q9NSE5;
DE   RecName: Full=Speriolin-like protein;
DE   AltName: Full=Spermatogenesis and centriole-associated protein 1-like protein;
GN   Name=SPATC1L; Synonyms=C21orf56;
//
ID   SPC24_HUMAN             Reviewed;         197 AA.
AC   Q8NBT2; B4DZZ7; C9JGC4;
DE   RecName: Full=Kinetochore protein Spc24;
DE            Short=hSpc24;
GN   Name=SPC24; Synonyms=SPBC24;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   SPC25_HUMAN             Reviewed;         224 AA.
AC   Q9HBM1; A8K4X8; D3DPC0;
DE   RecName: Full=Kinetochore protein Spc25;
DE            Short=hSpc25;
GN   Name=SPC25; Synonyms=SPBC25; ORFNames=AD024;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007052; P:mitotic spindle organization; IMP:UniProtKB.
//
ID   SPCS1_HUMAN             Reviewed;         102 AA.
AC   Q9Y6A9; B3KNF8; Q9BVW1;
DE   RecName: Full=Signal peptidase complex subunit 1;
DE            EC=3.4.-.-;
DE   AltName: Full=Microsomal signal peptidase 12 kDa subunit;
DE            Short=SPase 12 kDa subunit;
GN   Name=SPCS1; Synonyms=SPC12; ORFNames=HSPC033;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:UniProtKB.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SPCS2_HUMAN             Reviewed;         226 AA.
AC   Q15005; Q15507; Q3KQT0; Q641R4; Q6FG65; Q6IRX0; Q6P1P4; Q96HU9;
DE   RecName: Full=Signal peptidase complex subunit 2;
DE            EC=3.4.-.-;
DE   AltName: Full=Microsomal signal peptidase 25 kDa subunit;
DE            Short=SPase 25 kDa subunit;
GN   Name=SPCS2; Synonyms=KIAA0102, SPC25;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SPCS3_HUMAN             Reviewed;         180 AA.
AC   P61009; P12280; Q9H0S7;
DE   RecName: Full=Signal peptidase complex subunit 3;
DE            EC=3.4.-.-;
DE   AltName: Full=Microsomal signal peptidase 22/23 kDa subunit;
DE            Short=SPC22/23;
DE            Short=SPase 22/23 kDa subunit;
GN   Name=SPCS3; Synonyms=SPC22; ORFNames=UNQ1841/PRO3567;
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SPCS_HUMAN              Reviewed;         501 AA.
AC   Q9HD40; A8K8W1; Q0D2P3; Q17RT1; Q9NXZ5; Q9UGM9; Q9Y353;
DE   RecName: Full=O-phosphoseryl-tRNA(Sec) selenium transferase;
DE            EC=2.9.1.2;
DE   AltName: Full=Liver-pancreas antigen;
DE            Short=LP;
DE   AltName: Full=SLA-p35;
DE   AltName: Full=SLA/LP autoantigen;
DE   AltName: Full=Selenocysteine synthase;
DE            Short=Sec synthase;
DE   AltName: Full=Selenocysteinyl-tRNA(Sec) synthase;
DE   AltName: Full=Sep-tRNA:Sec-tRNA synthase;
DE            Short=SepSecS;
DE   AltName: Full=Soluble liver antigen;
DE            Short=SLA;
DE   AltName: Full=UGA suppressor tRNA-associated protein;
DE   AltName: Full=tRNA(Ser/Sec)-associated antigenic protein;
GN   Name=SEPSECS; Synonyms=TRNP48;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0016785; F:transferase activity, transferring selenium-containing groups; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; ISS:HGNC.
DR   GO; GO:0001514; P:selenocysteine incorporation; ISS:HGNC.
DR   GO; GO:0097056; P:selenocysteinyl-tRNA(Sec) biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   SPD2A_HUMAN             Reviewed;        1133 AA.
AC   Q5TCZ1; D3DR98; O43302; Q5TCZ2; Q5TDQ8;
DE   RecName: Full=SH3 and PX domain-containing protein 2A;
DE   AltName: Full=Adapter protein TKS5;
DE   AltName: Full=Five SH3 domain-containing protein;
DE   AltName: Full=SH3 multiple domains protein 1;
DE   AltName: Full=Tyrosine kinase substrate with five SH3 domains;
GN   Name=SH3PXD2A; Synonyms=FISH, KIAA0418, SH3MD1, TKS5;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
//
ID   SPD2B_HUMAN             Reviewed;         911 AA.
AC   A1X283; B6F0V2; Q9P2Q1;
DE   RecName: Full=SH3 and PX domain-containing protein 2B;
DE   AltName: Full=Adapter protein HOFI;
DE   AltName: Full=Factor for adipocyte differentiation 49;
DE   AltName: Full=Tyrosine kinase substrate with four SH3 domains;
GN   Name=SH3PXD2B; Synonyms=FAD49, KIAA1295, TKS4;
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IEA:Ensembl.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; ISS:UniProtKB.
DR   GO; GO:0060348; P:bone development; IMP:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.
DR   GO; GO:0001654; P:eye development; IMP:UniProtKB.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0071800; P:podosome assembly; ISS:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0072657; P:protein localization to membrane; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
//
ID   SPDE1_HUMAN             Reviewed;         336 AA.
AC   Q8NFV5; Q9NTH5;
DE   RecName: Full=Speedy protein E1;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;
GN   Name=SPDYE1; Synonyms=WBSCR19;
//
ID   SPDE2_HUMAN             Reviewed;         402 AA.
AC   Q495Y8; B4DY11;
DE   RecName: Full=Speedy protein E2;
GN   Name=SPDYE2;
//
ID   SPDE4_HUMAN             Reviewed;         237 AA.
AC   A6NLX3; B2RUZ6;
DE   RecName: Full=Speedy protein E4;
GN   Name=SPDYE4;
//
ID   SPDE5_HUMAN             Reviewed;         337 AA.
AC   A6NIY4;
DE   RecName: Full=Putative speedy protein E5;
GN   Name=SPDYE5;
//
ID   SPDE3_HUMAN             Reviewed;         549 AA.
AC   A6NKU9; Q495Y9; Q6PHC4;
DE   RecName: Full=Speedy protein E3;
GN   Name=SPDYE3;
//
ID   SPDE6_HUMAN             Reviewed;         402 AA.
AC   P0CI01;
DE   RecName: Full=Putative speedy protein E6;
GN   Name=SPDYE6;
//
ID   SPDE7_HUMAN             Reviewed;         208 AA.
AC   Q495Y7;
DE   RecName: Full=Putative speedy protein E7;
DE   AltName: Full=Speedy protein E7 pseudogene;
GN   Name=SPDYE7P;
//
ID   SPDEF_HUMAN             Reviewed;         335 AA.
AC   O95238; B4DWH8; F5H778;
DE   RecName: Full=SAM pointed domain-containing Ets transcription factor;
DE   AltName: Full=Prostate epithelium-specific Ets transcription factor;
DE            Short=Prostate-specific Ets;
DE   AltName: Full=Prostate-derived Ets factor;
GN   Name=SPDEF; Synonyms=PDEF, PSE;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0060576; P:intestinal epithelial cell development; IEA:Ensembl.
DR   GO; GO:0060480; P:lung goblet cell differentiation; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0010454; P:negative regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0010455; P:positive regulation of cell fate commitment; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   SPDL1_HUMAN             Reviewed;         402 AA.
AC   A6NME0;
DE   RecName: Full=Putative speedy protein-like protein LOC442572;
//
ID   SPDL3_HUMAN             Reviewed;         290 AA.
AC   A6NJR5;
DE   RecName: Full=Putative speedy protein-like protein 3;
//
ID   SPDL2_HUMAN             Reviewed;         312 AA.
AC   A6NNV3;
DE   RecName: Full=Putative speedy protein-like protein 2;
//
ID   SPDLY_HUMAN             Reviewed;         605 AA.
AC   Q96EA4; B4E393; C9JS47; Q8TEC8; Q9HD44; Q9NX97;
DE   RecName: Full=Protein Spindly;
DE            Short=hSpindly;
DE   AltName: Full=Arsenite-related gene 1 protein;
DE   AltName: Full=Coiled-coil domain-containing protein 99;
DE   AltName: Full=Rhabdomyosarcoma antigen MU-RMS-40.4A;
DE   AltName: Full=Spindle apparatus coiled-coil domain-containing protein 1;
GN   Name=SPDL1; Synonyms=CCDC99;
DR   GO; GO:0043515; F:kinetochore binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.
DR   GO; GO:0031577; P:spindle checkpoint; IEA:InterPro.
//
ID   SPDYA_HUMAN             Reviewed;         313 AA.
AC   Q5MJ70; Q53R05; Q5MJ69;
DE   RecName: Full=Speedy protein A;
DE   AltName: Full=Rapid inducer of G2/M progression in oocytes A;
DE            Short=RINGO A;
DE            Short=hSpy/Ringo A;
DE   AltName: Full=Speedy-1;
DE            Short=Spy1;
GN   Name=SPDYA; Synonyms=SPDY1, SPY1;
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IEA:Ensembl.
//
ID   SPDYC_HUMAN             Reviewed;         293 AA.
AC   Q5MJ68; B2RP32; B7ZMH7;
DE   RecName: Full=Speedy protein C;
DE   AltName: Full=Rapid inducer of G2/M progression in oocytes C;
DE            Short=RINGO C;
DE            Short=hSpy/Ringo C;
GN   Name=SPDYC;
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   SPE2B_HUMAN             Reviewed;         402 AA.
AC   A6NHP3; D6RBN0;
DE   RecName: Full=Speedy protein E2B;
GN   Name=SPDYE2B;
//
ID   SPE39_HUMAN             Reviewed;         493 AA.
AC   Q9H9C1; B4DPI6; O95434; Q9H7E1; Q9H9I9;
DE   RecName: Full=Spermatogenesis-defective protein 39 homolog;
DE            Short=hSPE-39;
DE   AltName: Full=VPS33B-interacting protein in apical-basolateral polarity regulator;
DE   AltName: Full=VPS33B-interacting protein in polarity and apical restriction;
GN   Name=VIPAS39; Synonyms=C14orf133, SPE39, VIPAR;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SPEB_HUMAN              Reviewed;         352 AA.
AC   Q9BSE5; Q5TDH1; Q9H5J3;
DE   RecName: Full=Agmatinase, mitochondrial;
DE            EC=3.5.3.11;
DE   AltName: Full=Agmatine ureohydrolase;
DE            Short=AUH;
DE   Flags: Precursor;
GN   Name=AGMAT;
DR   GO; GO:0008783; F:agmatinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0097055; P:agmatine biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0033388; P:putrescine biosynthetic process from arginine; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
//
ID   SPEE_HUMAN              Reviewed;         302 AA.
AC   P19623; B1AKP9; Q15511;
DE   RecName: Full=Spermidine synthase;
DE            Short=SPDSY;
DE            EC=2.5.1.16;
DE   AltName: Full=Putrescine aminopropyltransferase;
GN   Name=SRM; Synonyms=SPS1, SRML1;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004766; F:spermidine synthase activity; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008295; P:spermidine biosynthetic process; IDA:UniProtKB.
//
ID   SPEF1_HUMAN             Reviewed;         236 AA.
AC   Q9Y4P9; A5YM71; D3DVY0; Q5JX78;
DE   RecName: Full=Sperm flagellar protein 1;
GN   Name=SPEF1; Synonyms=C20orf28;
//
ID   SPEF2_HUMAN             Reviewed;        1822 AA.
AC   Q9C093; Q2TAC9; Q96LL6; Q9H5C7; Q9H5Q7;
DE   RecName: Full=Sperm flagellar protein 2;
DE   AltName: Full=Protein KPL2;
GN   Name=SPEF2; Synonyms=KIAA1770, KPL2;
DR   GO; GO:0035082; P:axoneme assembly; IEA:Ensembl.
DR   GO; GO:0048854; P:brain morphogenesis; IEA:Ensembl.
DR   GO; GO:0048702; P:embryonic neurocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0002520; P:immune system development; IEA:Ensembl.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0060541; P:respiratory system development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   SPEG_HUMAN              Reviewed;        3267 AA.
AC   Q15772; A8K0G6; A8MRU0; Q27J74; Q695L1; Q6FGA6; Q6ZQW1; Q6ZTL8;
AC   Q9P2P9;
DE   RecName: Full=Striated muscle preferentially expressed protein kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=Aortic preferentially expressed protein 1;
DE            Short=APEG-1;
GN   Name=SPEG; Synonyms=APEG1, KIAA1297;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0060541; P:respiratory system development; IEA:Ensembl.
//
ID   SPEM1_HUMAN             Reviewed;         309 AA.
AC   Q8N4L4;
DE   RecName: Full=Spermatid maturation protein 1;
GN   Name=SPEM1; Synonyms=C17orf83;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPERI_HUMAN             Reviewed;         591 AA.
AC   Q76KD6; B4DWW9; Q5U5I8; Q7Z6L7;
DE   RecName: Full=Speriolin;
DE   AltName: Full=Spermatogenesis and centriole-associated protein 1;
DE   AltName: Full=Spermatogenesis-associated protein 15;
DE   AltName: Full=Spermatogenic cell-specific Cdc20-binding protein;
GN   Name=SPATC1; Synonyms=SPATA15, SPRN;
//
ID   SPERT_HUMAN             Reviewed;         448 AA.
AC   Q8NA61; A8K8I5; Q8NHV2;
DE   RecName: Full=Spermatid-associated protein;
DE   AltName: Full=Protein chibby homolog 2;
GN   Name=SPERT; Synonyms=CBY2;
//
ID   SPESP_HUMAN             Reviewed;         350 AA.
AC   Q6UW49; Q8NG22; Q8WVH8;
DE   RecName: Full=Sperm equatorial segment protein 1;
DE            Short=ESP;
DE            Short=Equatorial segment protein;
DE            Short=SP-ESP;
DE   AltName: Full=Glycosylated 38 kDa sperm protein C-7/8;
DE   Flags: Precursor;
GN   Name=SPESP1; ORFNames=UNQ732/PRO1418;
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   SPF27_HUMAN             Reviewed;         225 AA.
AC   O75934; Q6FGS0;
DE   RecName: Full=Pre-mRNA-splicing factor SPF27;
DE   AltName: Full=Breast carcinoma-amplified sequence 2;
DE   AltName: Full=DNA amplified in mammary carcinoma 1 protein;
DE   AltName: Full=Spliceosome-associated protein SPF 27;
GN   Name=BCAS2; Synonyms=DAM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   SPF30_HUMAN             Reviewed;         238 AA.
AC   O75940; B2RA27; D3DRB1; Q5T3K6;
DE   RecName: Full=Survival of motor neuron-related-splicing factor 30;
DE   AltName: Full=30 kDa splicing factor SMNrp;
DE   AltName: Full=SMN-related protein;
DE   AltName: Full=Survival motor neuron domain-containing protein 1;
GN   Name=SMNDC1; Synonyms=SMNR, SPF30;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   SPF45_HUMAN             Reviewed;         401 AA.
AC   Q96I25; Q96GY6;
DE   RecName: Full=Splicing factor 45;
DE   AltName: Full=45 kDa-splicing factor;
DE   AltName: Full=RNA-binding motif protein 17;
GN   Name=RBM17; Synonyms=SPF45;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SPG16_HUMAN             Reviewed;         631 AA.
AC   Q8N0X2; Q498B7; Q658W1; Q68DB3; Q6I9Z6; Q8N9C7; Q9H601;
DE   RecName: Full=Sperm-associated antigen 16 protein;
DE   AltName: Full=Pf20 protein homolog;
GN   Name=SPAG16; Synonyms=PF20;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   SPG17_HUMAN             Reviewed;        2223 AA.
AC   Q6Q759; Q8NAZ1; Q9NT21;
DE   RecName: Full=Sperm-associated antigen 17;
DE   AltName: Full=Projection protein PF6 homolog;
GN   Name=SPAG17;
//
ID   SPG21_HUMAN             Reviewed;         308 AA.
AC   Q9NZD8; B4DW44; Q6ZMB6;
DE   RecName: Full=Maspardin;
DE   AltName: Full=Acid cluster protein 33;
DE   AltName: Full=Spastic paraplegia 21 autosomal recessive Mast syndrome protein;
DE   AltName: Full=Spastic paraplegia 21 protein;
GN   Name=SPG21; Synonyms=ACP33; ORFNames=BM-019, GL010;
DR   GO; GO:0042609; F:CD4 receptor binding; IPI:UniProtKB.
DR   GO; GO:0050851; P:antigen receptor-mediated signaling pathway; IC:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   SPG20_HUMAN             Reviewed;         666 AA.
AC   Q8N0X7; O60349; Q86Y67; Q9H1T2; Q9H1T3;
DE   RecName: Full=Spartin;
DE   AltName: Full=Spastic paraplegia 20 protein;
DE   AltName: Full=Trans-activated by hepatitis C virus core protein 1;
GN   Name=SPG20; Synonyms=KIAA0610, TAHCCP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0009838; P:abscission; IMP:UniProtKB.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IMP:UniProtKB.
DR   GO; GO:0034389; P:lipid particle organization; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0048698; P:negative regulation of collateral sprouting in absence of injury; IEA:Ensembl.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IMP:MGI.
//
ID   SPG7_HUMAN              Reviewed;         795 AA.
AC   Q9UQ90; O75756; Q2TB70; Q58F00; Q96IB0;
DE   RecName: Full=Paraplegin;
DE            EC=3.4.24.-;
DE   AltName: Full=Spastic paraplegia 7 protein;
GN   Name=SPG7; Synonyms=CAR, CMAR, PGN;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:MGI.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008089; P:anterograde axon cargo transport; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
//
ID   SPGOS_HUMAN             Reviewed;          52 AA.
AC   P0CW21;
DE   RecName: Full=Putative uncharacterized protein SPG20OS;
DE   AltName: Full=SPG20 opposite strand transcript protein;
GN   Name=SPG20OS; Synonyms=C13orf43;
//
ID   SPHAR_HUMAN             Reviewed;          63 AA.
AC   Q15513; Q4EW09; Q6NSB9;
DE   RecName: Full=Protein SPHAR;
DE   AltName: Full=S-phase response protein;
GN   Name=SPHAR;
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
//
ID   SPHK1_HUMAN             Reviewed;         384 AA.
AC   Q9NYA1; Q8N632; Q96GK1; Q9HD92; Q9NY70; Q9NYL3;
DE   RecName: Full=Sphingosine kinase 1;
DE            Short=SK 1;
DE            Short=SPK 1;
DE            EC=2.7.1.91;
GN   Name=SPHK1; Synonyms=SPHK, SPK;
DR   GuidetoPHARMACOLOGY; 2204; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0017050; F:D-erythro-sphingosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IPI:BHF-UCL.
DR   GO; GO:0008481; F:sphinganine kinase activity; IDA:MGI.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0019371; P:cyclooxygenase pathway; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:UniProtKB.
DR   GO; GO:0046834; P:lipid phosphorylation; IDA:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:MGI.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0001956; P:positive regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0032651; P:regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0010803; P:regulation of tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0014075; P:response to amine; IEA:Ensembl.
DR   GO; GO:0033198; P:response to ATP; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046521; P:sphingoid catabolic process; NAS:UniProtKB.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006670; P:sphingosine metabolic process; IDA:UniProtKB.
//
ID   SPHK2_HUMAN             Reviewed;         654 AA.
AC   Q9NRA0; A0T4C8; B4DU87; Q9BRN1; Q9H0Q2; Q9NWU7;
DE   RecName: Full=Sphingosine kinase 2;
DE            Short=SK 2;
DE            Short=SPK 2;
DE            EC=2.7.1.91;
GN   Name=SPHK2;
DR   GuidetoPHARMACOLOGY; 2205; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017050; F:D-erythro-sphingosine kinase activity; IEA:Ensembl.
DR   GO; GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017016; F:Ras GTPase binding; NAS:UniProtKB.
DR   GO; GO:0008481; F:sphinganine kinase activity; NAS:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0046834; P:lipid phosphorylation; NAS:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006669; P:sphinganine-1-phosphate biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006670; P:sphingosine metabolic process; IEA:Ensembl.
//
ID   SPHM_HUMAN              Reviewed;         502 AA.
AC   P51688; A8K5E2;
DE   RecName: Full=N-sulphoglucosamine sulphohydrolase;
DE            EC=3.10.1.1;
DE   AltName: Full=Sulfoglucosamine sulfamidase;
DE   AltName: Full=Sulphamidase;
DE   Flags: Precursor;
GN   Name=SGSH; Synonyms=HSS;
DR   GO; GO:0003824; F:catalytic activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016250; F:N-sulfoglucosamine sulfohydrolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006029; P:proteoglycan metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SPI2A_HUMAN             Reviewed;         258 AA.
AC   Q99865; O75650; Q6IPW2; Q9UJJ0;
DE   RecName: Full=Spindlin-2A;
DE   AltName: Full=Protein DXF34;
DE   AltName: Full=Spindlin-like protein 2A;
DE            Short=SPIN-2;
DE            Short=SPIN-2A;
GN   Name=SPIN2A; Synonyms=DXF34, SPIN2;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007276; P:gamete generation; IEA:InterPro.
//
ID   SPI1_HUMAN              Reviewed;         270 AA.
AC   P17947;
DE   RecName: Full=Transcription factor PU.1;
DE   AltName: Full=31 kDa-transforming protein;
GN   Name=SPI1;
DR   GO; GO:0001047; F:core promoter binding; IDA:UniProtKB.
DR   GO; GO:0051525; F:NFAT protein binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0001205; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0060033; P:anatomical structure regression; IEA:Ensembl.
DR   GO; GO:1902262; P:apoptotic process involved in patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0030851; P:granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043966; P:histone H3 acetylation; IMP:UniProtKB.
DR   GO; GO:0044027; P:hypermethylation of CpG island; IDA:UniProtKB.
DR   GO; GO:0030098; P:lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:UniProtKB.
DR   GO; GO:0090241; P:negative regulation of histone H4 acetylation; IMP:UniProtKB.
DR   GO; GO:0045347; P:negative regulation of MHC class II biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0045646; P:regulation of erythrocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   SPI2B_HUMAN             Reviewed;         258 AA.
AC   Q9BPZ2; Q7Z2M0;
DE   RecName: Full=Spindlin-2B;
DE   AltName: Full=Spindlin-like protein 2B;
DE            Short=SPIN-2;
DE            Short=SPIN-2B;
GN   Name=SPIN2B; Synonyms=SPIN2;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007276; P:gamete generation; IEA:InterPro.
//
ID   SPI2_HUMAN              Reviewed;         405 AA.
AC   O75830;
DE   RecName: Full=Serpin I2;
DE   AltName: Full=Myoepithelium-derived serine protease inhibitor;
DE   AltName: Full=Pancpin;
DE   AltName: Full=Pancreas-specific protein TSA2004;
DE   AltName: Full=Peptidase inhibitor 14;
DE            Short=PI-14;
DE   Flags: Precursor;
GN   Name=SERPINI2; Synonyms=MEPI, PI14;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   SPIB_HUMAN              Reviewed;         262 AA.
AC   Q01892; A8K9C9; B4DUG6; Q15359;
DE   RecName: Full=Transcription factor Spi-B;
GN   Name=SPIB;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   SPICE_HUMAN             Reviewed;         855 AA.
AC   Q8N0Z3; D3DN72; Q8WUX6;
DE   RecName: Full=Spindle and centriole-associated protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 52;
DE   AltName: Full=Spindle and centriole-associated protein;
GN   Name=SPICE1; Synonyms=CCDC52, SPICE;
DR   GO; GO:0051310; P:metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0046599; P:regulation of centriole replication; IMP:UniProtKB.
DR   GO; GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
//
ID   SPIDR_HUMAN             Reviewed;         915 AA.
AC   Q14159; Q96BI5;
DE   RecName: Full=DNA repair-scaffolding protein;
DE   AltName: Full=Scaffolding protein involved in DNA repair;
GN   Name=SPIDR; Synonyms=KIAA0146;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0072757; P:cellular response to camptothecin; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0072711; P:cellular response to hydroxyurea; IDA:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:2000781; P:positive regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IDA:UniProtKB.
DR   GO; GO:0070202; P:regulation of establishment of protein localization to chromosome; IDA:UniProtKB.
//
ID   SPIC_HUMAN              Reviewed;         248 AA.
AC   Q8N5J4;
DE   RecName: Full=Transcription factor Spi-C;
GN   Name=SPIC;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   SPIN1_HUMAN             Reviewed;         262 AA.
AC   Q9Y657; A8K0X6; B3KRQ4; Q7KZJ8; Q9GZT2; Q9H0N7;
DE   RecName: Full=Spindlin-1;
DE   AltName: Full=Ovarian cancer-related protein;
DE   AltName: Full=Spindlin1;
GN   Name=SPIN1; Synonyms=OCR, SPIN;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007276; P:gamete generation; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0009303; P:rRNA transcription; IDA:UniProtKB.
//
ID   SPIN3_HUMAN             Reviewed;         258 AA.
AC   Q5JUX0; B2RUW3; B7Z8W2; Q8N5D9;
DE   RecName: Full=Spindlin-3;
DE   AltName: Full=Spindlin-like protein 3;
DE            Short=SPIN-3;
GN   Name=SPIN3;
DR   GO; GO:0007276; P:gamete generation; IEA:InterPro.
//
ID   SPIN4_HUMAN             Reviewed;         249 AA.
AC   Q56A73; B3KX90; Q5JUL2;
DE   RecName: Full=Spindlin-4;
GN   Name=SPIN4;
DR   GO; GO:0007276; P:gamete generation; IEA:InterPro.
//
ID   SPIR1_HUMAN             Reviewed;         756 AA.
AC   Q08AE8; A8K2B5; J3KQ50; J3KQR5; Q1RMD4; Q8NDP1; Q9NQ71; Q9ULT4;
DE   RecName: Full=Protein spire homolog 1;
DE            Short=Spir-1;
GN   Name=SPIRE1; Synonyms=KIAA1135, SPIR1;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0036089; P:cleavage furrow formation; ISS:UniProtKB.
DR   GO; GO:0051295; P:establishment of meiotic spindle localization; IMP:UniProtKB.
DR   GO; GO:0070649; P:formin-nucleated actin cable assembly; ISS:UniProtKB.
DR   GO; GO:0048193; P:Golgi vesicle transport; IEA:Ensembl.
DR   GO; GO:0046907; P:intracellular transport; ISS:UniProtKB.
DR   GO; GO:0040038; P:polar body extrusion after meiotic divisions; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   SPIR2_HUMAN             Reviewed;         714 AA.
AC   Q8WWL2; A4QPB1; Q2TA98; Q6P433; Q8ND47; Q96JJ5;
DE   RecName: Full=Protein spire homolog 2;
DE            Short=Spir-2;
GN   Name=SPIRE2; Synonyms=KIAA1832, SPIR2;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0036089; P:cleavage furrow formation; ISS:UniProtKB.
DR   GO; GO:0051295; P:establishment of meiotic spindle localization; IMP:UniProtKB.
DR   GO; GO:0070649; P:formin-nucleated actin cable assembly; ISS:UniProtKB.
DR   GO; GO:0046907; P:intracellular transport; ISS:UniProtKB.
DR   GO; GO:0040038; P:polar body extrusion after meiotic divisions; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   SPIT1_HUMAN             Reviewed;         529 AA.
AC   O43278; Q7Z7D2;
DE   RecName: Full=Kunitz-type protease inhibitor 1;
DE   AltName: Full=Hepatocyte growth factor activator inhibitor type 1;
DE            Short=HAI-1;
DE   Flags: Precursor;
GN   Name=SPINT1; Synonyms=HAI1; ORFNames=UNQ223/PRO256;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0060670; P:branching involved in labyrinthine layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0060674; P:placenta blood vessel development; IEA:Ensembl.
//
ID   SPIT2_HUMAN             Reviewed;         252 AA.
AC   O43291; A8K667; B4DLU1; O00271; O14895; Q5TZQ3; Q969E0;
DE   RecName: Full=Kunitz-type protease inhibitor 2;
DE   AltName: Full=Hepatocyte growth factor activator inhibitor type 2;
DE            Short=HAI-2;
DE   AltName: Full=Placental bikunin;
DE   Flags: Precursor;
GN   Name=SPINT2; Synonyms=HAI2, KOP;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   SPIT4_HUMAN             Reviewed;          99 AA.
AC   Q6UDR6; Q9BQN3;
DE   RecName: Full=Kunitz-type protease inhibitor 4;
DE   Flags: Precursor;
GN   Name=SPINT4; Synonyms=C20orf137;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   SPIT3_HUMAN             Reviewed;          89 AA.
AC   P49223; A6NCQ6; Q6UDR8; Q96KK2;
DE   RecName: Full=Kunitz-type protease inhibitor 3;
DE   AltName: Full=HKIB9;
DE   Flags: Precursor;
GN   Name=SPINT3;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   SPKAP_HUMAN             Reviewed;        1700 AA.
AC   Q2M3C7; Q68DA3; Q68DR8; Q9C0I5;
DE   RecName: Full=A-kinase anchor protein SPHKAP;
DE   AltName: Full=SPHK1-interactor and AKAP domain-containing protein;
DE   AltName: Full=Sphingosine kinase type 1-interacting protein;
GN   Name=SPHKAP; Synonyms=KIAA1678, SKIP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051018; F:protein kinase A binding; IDA:UniProtKB.
//
ID   SPN1_HUMAN              Reviewed;         360 AA.
AC   O95149; A6NE34; A8K0B0; D3DW76;
DE   RecName: Full=Snurportin-1;
DE   AltName: Full=RNA U transporter 1;
GN   Name=SNUPN; Synonyms=RNUT1, SPN1;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0000339; F:RNA cap binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0061015; P:snRNA import into nucleus; IEA:InterPro.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
//
ID   SPN90_HUMAN             Reviewed;         722 AA.
AC   Q9NZQ3; B4DFL5; Q6GU34; Q6SPF3; Q8TC10; Q9UGM8;
DE   RecName: Full=NCK-interacting protein with SH3 domain;
DE   AltName: Full=54 kDa VacA-interacting protein;
DE   AltName: Full=54 kDa vimentin-interacting protein;
DE            Short=VIP54;
DE   AltName: Full=90 kDa SH3 protein interacting with Nck;
DE   AltName: Full=AF3p21;
DE   AltName: Full=Dia-interacting protein 1;
DE            Short=DIP-1;
DE   AltName: Full=Diaphanous protein-interacting protein;
DE   AltName: Full=SH3 adapter protein SPIN90;
DE   AltName: Full=WASP-interacting SH3-domain protein;
DE            Short=WISH;
DE   AltName: Full=Wiskott-Aldrich syndrome protein-interacting protein;
GN   Name=NCKIPSD; Synonyms=AF3P21, SPIN90;
DR   GO; GO:0008092; F:cytoskeletal protein binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   SPNS1_HUMAN             Reviewed;         528 AA.
AC   Q9H2V7; B5MDM9; Q6P182; Q71RB5; Q7L541; Q86VU7; Q8N953; Q8TCS5;
AC   Q9BRN5;
DE   RecName: Full=Protein spinster homolog 1;
DE   AltName: Full=HSpin1;
DE   AltName: Full=Spinster-like protein 1;
GN   Name=SPNS1; Synonyms=SPIN1; ORFNames=PP20300;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SPNS2_HUMAN             Reviewed;         549 AA.
AC   Q8IVW8; B9A1T3;
DE   RecName: Full=Protein spinster homolog 2;
GN   Name=SPNS2;
DR   GO; GO:0046624; F:sphingolipid transporter activity; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0072676; P:lymphocyte migration; IEA:Ensembl.
DR   GO; GO:0048073; P:regulation of eye pigmentation; IEA:Ensembl.
DR   GO; GO:0002920; P:regulation of humoral immune response; IEA:Ensembl.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:Ensembl.
DR   GO; GO:0003376; P:sphingosine-1-phosphate signaling pathway; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SPNS3_HUMAN             Reviewed;         512 AA.
AC   Q6ZMD2; Q8IZ31;
DE   RecName: Full=Protein spinster homolog 3;
GN   Name=SPNS3;
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SPNXA_HUMAN             Reviewed;          97 AA.
AC   Q9NS26; Q5JWI0;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome A;
DE   AltName: Full=Cancer/testis antigen 11.1;
DE            Short=CT11.1;
DE   AltName: Full=Nuclear-associated protein SPAN-Xa;
DE            Short=SPAN-X;
DE            Short=SPANX-A;
DE   AltName: Full=SPANX family member A;
GN   Name=SPANXA1; Synonyms=SPANXA;
GN   and
GN   Name=SPANXA2;
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   SPNXC_HUMAN             Reviewed;          97 AA.
AC   Q9NY87; Q32WL9; Q5JX88;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome C;
DE   AltName: Full=Cancer/testis antigen 11.3;
DE            Short=CT11.3;
DE   AltName: Full=Cancer/testis-associated protein CTp11;
DE   AltName: Full=Nuclear-associated protein SPAN-Xc;
DE            Short=SPANX-C;
DE   AltName: Full=SPANX family member C;
GN   Name=SPANXC;
//
ID   SPNXD_HUMAN             Reviewed;          97 AA.
AC   Q9BXN6; Q5JWI1;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome D;
DE   AltName: Full=Cancer/testis antigen 11.4;
DE            Short=CT11.4;
DE   AltName: Full=Nuclear-associated protein SPAN-Xd;
DE            Short=SPANX-D;
DE   AltName: Full=SPANX family member D;
GN   Name=SPANXD;
//
ID   SPNXE_HUMAN             Reviewed;          97 AA.
AC   Q8TAD1; Q32WL2; Q32WM0; Q9BS24;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome E;
DE   AltName: Full=Nuclear-associated protein SPAN-Xe;
DE            Short=SPANX-E;
DE   AltName: Full=SPANX family member E;
GN   Name=SPANXE;
//
ID   SPNXB_HUMAN             Reviewed;         103 AA.
AC   Q9NS25; B2RPP2; Q32WQ7; Q5JYZ7; Q8TAD5;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome B/F;
DE   AltName: Full=Cancer/testis antigen 11.2;
DE            Short=CT11.2;
DE   AltName: Full=Nuclear-associated protein SPAN-Xb;
DE            Short=SPANX-B;
DE   AltName: Full=Nuclear-associated protein SPAN-Xf;
DE            Short=SPANX-F;
DE   AltName: Full=SPANX family member B/F;
GN   Name=SPANXB1; Synonyms=SPANXB;
GN   and
GN   Name=SPANXB2;
GN   and
GN   Name=SPANXF1;
DR   GO; GO:0007286; P:spermatid development; NAS:UniProtKB.
//
ID   SPO11_HUMAN             Reviewed;         396 AA.
AC   Q9Y5K1; Q5TCI1; Q8N4V0; Q9NQM7; Q9NQM8;
DE   RecName: Full=Meiotic recombination protein SPO11;
DE   AltName: Full=Cancer/testis antigen 35;
DE            Short=CT35;
GN   Name=SPO11;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0034502; P:protein localization to chromosome; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   SPOC1_HUMAN             Reviewed;        1216 AA.
AC   Q6ZMY3; Q24JU3; Q6PI90; Q8N869; Q8N8U0; Q8NBC6; Q96LN6;
DE   RecName: Full=SPOC domain-containing protein 1;
GN   Name=SPOCD1;
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   SPON1_HUMAN             Reviewed;         807 AA.
AC   Q9HCB6; A8K6W5; O94862; Q8NCD7; Q8WUR5;
DE   RecName: Full=Spondin-1;
DE   AltName: Full=F-spondin;
DE   AltName: Full=Vascular smooth muscle cell growth-promoting factor;
DE   Flags: Precursor;
GN   Name=SPON1; Synonyms=KIAA0762, VSGP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SPON2_HUMAN             Reviewed;         331 AA.
AC   Q9BUD6; D3DVN9; Q4W5N4; Q9ULW1;
DE   RecName: Full=Spondin-2;
DE   AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 1;
DE            Short=DIL-1;
DE   AltName: Full=Mindin;
DE   Flags: Precursor;
GN   Name=SPON2; Synonyms=DIL1; ORFNames=UNQ435/PRO866;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   SPOPL_HUMAN             Reviewed;         392 AA.
AC   Q6IQ16;
DE   RecName: Full=Speckle-type POZ protein-like;
DE   AltName: Full=HIB homolog 2;
DE   AltName: Full=Roadkill homolog 2;
GN   Name=SPOPL;
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SPOP_HUMAN              Reviewed;         374 AA.
AC   O43791; B2R6S3; D3DTW7; Q53HJ1;
DE   RecName: Full=Speckle-type POZ protein;
DE   AltName: Full=HIB homolog 1;
DE   AltName: Full=Roadkill homolog 1;
GN   Name=SPOP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SPOT1_HUMAN             Reviewed;         137 AA.
AC   Q8N9U9;
DE   RecName: Full=Putative uncharacterized protein SPANXA2-OT1;
GN   Name=SPANXA2-OT1; Synonyms=CXorf18;
//
ID   SPP24_HUMAN             Reviewed;         211 AA.
AC   Q13103; A4QMV3; Q3B892; Q546M5;
DE   RecName: Full=Secreted phosphoprotein 24;
DE            Short=Spp-24;
DE   AltName: Full=Secreted phosphoprotein 2;
DE   Flags: Precursor;
GN   Name=SPP2; Synonyms=SPP24;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0046849; P:bone remodeling; IEA:InterPro.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   SPP2A_HUMAN             Reviewed;         520 AA.
AC   Q8TCT8; B2RDS0; Q8TAW1; Q96SZ8;
DE   RecName: Full=Signal peptide peptidase-like 2A;
DE            Short=SPP-like 2A;
DE            Short=SPPL2a;
DE            EC=3.4.23.-;
DE   AltName: Full=Intramembrane protease 3;
DE            Short=IMP-3;
DE   AltName: Full=Presenilin-like protein 2;
DE   Flags: Precursor;
GN   Name=SPPL2A; Synonyms=IMP3, PSL2; ORFNames=PSEC0147;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; IMP:UniProtKB.
//
ID   SPP2C_HUMAN             Reviewed;         684 AA.
AC   Q8IUH8; Q8TC67; Q8WVZ6;
DE   RecName: Full=Signal peptide peptidase-like 2C;
DE            Short=SPP-like 2C;
DE            Short=SPPL2c;
DE            EC=3.4.23.-;
DE   AltName: Full=Intramembrane protease 5;
DE            Short=IMP-5;
DE   Flags: Precursor;
GN   Name=SPPL2C; Synonyms=IMP5;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
//
ID   SPP2B_HUMAN             Reviewed;         592 AA.
AC   Q8TCT7; D6W609; O60365; Q567S3; Q8IUH9; Q9BUY6; Q9H3M4; Q9NPN2;
AC   Q9P1Z6;
DE   RecName: Full=Signal peptide peptidase-like 2B;
DE            Short=SPP-like 2B;
DE            Short=SPPL2b;
DE            EC=3.4.23.-;
DE   AltName: Full=Intramembrane protease 4;
DE            Short=IMP-4;
DE   AltName: Full=Presenilin homologous protein 4;
DE            Short=PSH4;
DE   AltName: Full=Presenilin-like protein 1;
DE   Flags: Precursor;
GN   Name=SPPL2B; Synonyms=IMP4, KIAA1532, PSL1;
DR   GO; GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; IDA:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; IMP:UniProtKB.
//
ID   SPPL3_HUMAN             Reviewed;         385 AA.
AC   Q8TCT6; Q3MJ04; Q8TAU4; Q96DD9;
DE   RecName: Full=Signal peptide peptidase-like 3;
DE            Short=SPP-like 3;
DE            EC=3.4.23.-;
DE   AltName: Full=Intramembrane protease 2;
DE            Short=IMP-2;
DE   AltName: Full=Presenilin homologous protein 1;
DE            Short=PSH1;
DE   AltName: Full=Presenilin-like protein 4;
GN   Name=SPPL3; Synonyms=IMP2, PSL4;
DR   GO; GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
//
ID   SPR1A_HUMAN             Reviewed;          89 AA.
AC   P35321; B1AN47; D3DV31; Q2M303; Q9UDG4;
DE   RecName: Full=Cornifin-A;
DE   AltName: Full=19 kDa pancornulin;
DE   AltName: Full=SPRK;
DE   AltName: Full=Small proline-rich protein IA;
DE            Short=SPR-IA;
GN   Name=SPRR1A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
//
ID   SPR1B_HUMAN             Reviewed;          89 AA.
AC   P22528; B2R5H7; P22529; P22530; Q5T524;
DE   RecName: Full=Cornifin-B;
DE   AltName: Full=14.9 kDa pancornulin;
DE   AltName: Full=Small proline-rich protein IB;
DE            Short=SPR-IB;
GN   Name=SPRR1B;
DR   GO; GO:0030674; F:protein binding, bridging; IDA:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IDA:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
//
ID   SPR2A_HUMAN             Reviewed;          72 AA.
AC   P35326; B2R4T3; D3DV35; Q5T529;
DE   RecName: Full=Small proline-rich protein 2A;
DE            Short=SPR-2A;
DE   AltName: Full=2-1;
GN   Name=SPRR2A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
//
ID   SPR2B_HUMAN             Reviewed;          72 AA.
AC   P35325; Q5T528;
DE   RecName: Full=Small proline-rich protein 2B;
DE            Short=SPR-2B;
GN   Name=SPRR2B;
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
//
ID   SPR2E_HUMAN             Reviewed;          72 AA.
AC   P22531; Q5T9T4; Q96RM2;
DE   RecName: Full=Small proline-rich protein 2E;
DE            Short=SPR-2E;
DE   AltName: Full=Small proline-rich protein II;
DE            Short=SPR-II;
GN   Name=SPRR2E;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   SPR2D_HUMAN             Reviewed;          72 AA.
AC   P22532; A4QN03; A8K5K2; D3DV33; Q5T523; Q96RM3;
DE   RecName: Full=Small proline-rich protein 2D;
DE            Short=SPR-2D;
DE   AltName: Full=Small proline-rich protein II;
DE            Short=SPR-II;
GN   Name=SPRR2D;
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   SPR2G_HUMAN             Reviewed;          73 AA.
AC   Q9BYE4;
DE   RecName: Full=Small proline-rich protein 2G;
DE            Short=SPR-2G;
GN   Name=SPRR2G;
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
//
ID   SPR2F_HUMAN             Reviewed;          72 AA.
AC   Q96RM1; Q5T9T3;
DE   RecName: Full=Small proline-rich protein 2F;
DE            Short=SPR-2F;
GN   Name=SPRR2F;
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
//
ID   SPRC_HUMAN              Reviewed;         303 AA.
AC   P09486; D3DQH9; Q6IBK4;
DE   RecName: Full=SPARC;
DE   AltName: Full=Basement-membrane protein 40;
DE            Short=BM-40;
DE   AltName: Full=Osteonectin;
DE            Short=ON;
DE   AltName: Full=Secreted protein acidic and rich in cysteine;
DE   Flags: Precursor;
GN   Name=SPARC; Synonyms=ON;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0005518; F:collagen binding; TAS:ProtInc.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0046686; P:response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0033591; P:response to L-ascorbic acid; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SPRE1_HUMAN             Reviewed;         444 AA.
AC   Q7Z699; B2RPJ8; Q05D53; Q8N256;
DE   RecName: Full=Sprouty-related, EVH1 domain-containing protein 1;
DE            Short=Spred-1;
DE            Short=hSpred1;
GN   Name=SPRED1;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0030291; F:protein serine/threonine kinase inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0005173; F:stem cell factor receptor binding; ISS:UniProtKB.
DR   GO; GO:0000188; P:inactivation of MAPK activity; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:BHF-UCL.
DR   GO; GO:0090311; P:regulation of protein deacetylation; ISS:BHF-UCL.
//
ID   SPRE2_HUMAN             Reviewed;         418 AA.
AC   Q7Z698; A1L3V4; B7Z5K7; D6W5F7; E9PEP0; Q2NKX6;
DE   RecName: Full=Sprouty-related, EVH1 domain-containing protein 2;
DE            Short=Spred-2;
GN   Name=SPRED2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0030291; F:protein serine/threonine kinase inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0005173; F:stem cell factor receptor binding; ISS:UniProtKB.
DR   GO; GO:0000188; P:inactivation of MAPK activity; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; ISS:BHF-UCL.
DR   GO; GO:0090311; P:regulation of protein deacetylation; ISS:BHF-UCL.
//
ID   SPRE3_HUMAN             Reviewed;         410 AA.
AC   Q2MJR0; Q2MJR1;
DE   RecName: Full=Sprouty-related, EVH1 domain-containing protein 3;
DE            Short=Spred-3;
GN   Name=SPRED3; Synonyms=EVE-3;
DR   GO; GO:0000188; P:inactivation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
//
ID   SPRE_HUMAN              Reviewed;         261 AA.
AC   P35270; A8K741; D6W5H2; Q53GI9; Q9UBB1;
DE   RecName: Full=Sepiapterin reductase;
DE            Short=SPR;
DE            EC=1.1.1.153;
GN   Name=SPR;
DR   GO; GO:0004033; F:aldo-keto reductase (NADP) activity; TAS:UniProtKB.
DR   GO; GO:0050661; F:NADP binding; TAS:UniProtKB.
DR   GO; GO:0004757; F:sepiapterin reductase activity; ISS:UniProtKB.
DR   GO; GO:0006809; P:nitric oxide biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; TAS:UniProtKB.
//
ID   SPRL1_HUMAN             Reviewed;         664 AA.
AC   Q14515; Q14800;
DE   RecName: Full=SPARC-like protein 1;
DE   AltName: Full=High endothelial venule protein;
DE            Short=Hevin;
DE   AltName: Full=MAST 9;
DE   Flags: Precursor;
GN   Name=SPARCL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   SPRN_HUMAN              Reviewed;         151 AA.
AC   Q5BIV9;
DE   RecName: Full=Shadow of prion protein;
DE            Short=Protein shadoo;
DE   Flags: Precursor;
GN   Name=SPRN; Synonyms=SHO;
//
ID   SPRR3_HUMAN             Reviewed;         169 AA.
AC   Q9UBC9; A5YKK8; B2R4G8; D3DV32; O75597; Q4ZGI7; Q5T525; Q8NET7;
AC   Q9UDG3;
DE   RecName: Full=Small proline-rich protein 3;
DE   AltName: Full=22 kDa pancornulin;
DE   AltName: Full=Cornifin beta;
DE   AltName: Full=Esophagin;
GN   Name=SPRR3; Synonyms=SPRC;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; TAS:UniProtKB.
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; NAS:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
DR   GO; GO:0042060; P:wound healing; TAS:UniProtKB.
//
ID   SPRR4_HUMAN             Reviewed;          79 AA.
AC   Q96PI1; Q2M1Y7; Q5T522;
DE   RecName: Full=Small proline-rich protein 4;
GN   Name=SPRR4;
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
//
ID   SPRTN_HUMAN             Reviewed;         489 AA.
AC   Q9H040; B1AKT0; B5MEF7; Q5TE78; Q6UWW6; Q96BC5; Q96KA0;
DE   RecName: Full=SprT-like domain-containing protein Spartan;
DE   AltName: Full=DNA damage protein targeting VCP;
DE            Short=DVC1;
DE   AltName: Full=Protein with SprT-like domain at the N terminus;
DE            Short=Spartan;
GN   Name=SPRTN; Synonyms=C1orf124, DVC1; ORFNames=UNQ1880/PRO4323;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0019985; P:translesion synthesis; IDA:UniProtKB.
//
ID   SPRY3_HUMAN             Reviewed;         442 AA.
AC   Q8NCJ5; B9EG99; Q96SK5;
DE   RecName: Full=SPRY domain-containing protein 3;
GN   Name=SPRYD3;
//
ID   SPRY4_HUMAN             Reviewed;         207 AA.
AC   Q8WW59; A8K7A5;
DE   RecName: Full=SPRY domain-containing protein 4;
GN   Name=SPRYD4;
//
ID   SPRY7_HUMAN             Reviewed;         196 AA.
AC   Q5W111; A8K3G1; O60648; Q8TBG8; Q96T69;
DE   RecName: Full=SPRY domain-containing protein 7;
DE   AltName: Full=Chronic lymphocytic leukemia deletion region gene 6 protein;
DE            Short=CLL deletion region gene 6 protein;
GN   Name=SPRYD7; Synonyms=C13orf1, CLLD6;
//
ID   SPS1_HUMAN              Reviewed;         392 AA.
AC   P49903; B4DWK0; D3DRS9; D6PSQ9; Q5T5U8; Q5T5U9; Q9BVT4;
DE   RecName: Full=Selenide, water dikinase 1;
DE            EC=2.7.9.3;
DE   AltName: Full=Selenium donor protein 1;
DE   AltName: Full=Selenophosphate synthase 1;
GN   Name=SEPHS1; Synonyms=SELD, SPS, SPS1;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004756; F:selenide, water dikinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
//
ID   SPS2_HUMAN              Reviewed;         448 AA.
AC   Q99611; Q9BUQ2;
DE   RecName: Full=Selenide, water dikinase 2;
DE            EC=2.7.9.3;
DE   AltName: Full=Selenium donor protein 2;
DE   AltName: Full=Selenophosphate synthase 2;
GN   Name=SEPHS2; Synonyms=SPS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004756; F:selenide, water dikinase activity; NAS:UniProtKB.
DR   GO; GO:0016260; P:selenocysteine biosynthetic process; NAS:UniProtKB.
//
ID   SPS2L_HUMAN             Reviewed;         558 AA.
AC   Q9NUQ6; A8K381; B4DRE6; B4DT67; B7WNZ7; Q53T22; Q8WV53; Q8WYG1;
AC   Q9NTW4;
DE   RecName: Full=SPATS2-like protein;
DE   AltName: Full=DNA polymerase-transactivated protein 6;
DE   AltName: Full=Stress granule and nucleolar protein;
DE            Short=SGNP;
GN   Name=SPATS2L; Synonyms=DNAPTP6; ORFNames=SP1224;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   SPSB1_HUMAN             Reviewed;         273 AA.
AC   Q96BD6; A2A275; Q59FA1; Q5TIH9; Q9BRY9; Q9H6C5;
DE   RecName: Full=SPRY domain-containing SOCS box protein 1;
DE            Short=SSB-1;
GN   Name=SPSB1; Synonyms=SSB1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SPSB2_HUMAN             Reviewed;         263 AA.
AC   Q99619; D3DUT0;
DE   RecName: Full=SPRY domain-containing SOCS box protein 2;
DE            Short=SSB-2;
DE   AltName: Full=Gene-rich cluster protein C9;
GN   Name=SPSB2; Synonyms=GRCC9, SSB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SPSB3_HUMAN             Reviewed;         355 AA.
AC   Q6PJ21; D3DU78; Q49A96; Q86X18; Q8WXK5; Q96IE6; Q96RY2;
DE   RecName: Full=SPRY domain-containing SOCS box protein 3;
DE            Short=SSB-3;
GN   Name=SPSB3; Synonyms=C16orf31, SSB3;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SPSB4_HUMAN             Reviewed;         273 AA.
AC   Q96A44;
DE   RecName: Full=SPRY domain-containing SOCS box protein 4;
DE            Short=SSB-4;
GN   Name=SPSB4; Synonyms=SSB4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SPSY_HUMAN              Reviewed;         366 AA.
AC   P52788; A6NHA7; A6NI34; B2R9M0; O00544; Q9UQS1;
DE   RecName: Full=Spermine synthase;
DE            Short=SPMSY;
DE            EC=2.5.1.22;
DE   AltName: Full=Spermidine aminopropyltransferase;
GN   Name=SMS;
DR   GO; GO:0004766; F:spermidine synthase activity; TAS:ProtInc.
DR   GO; GO:0016768; F:spermine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0006555; P:methionine metabolic process; TAS:ProtInc.
DR   GO; GO:0006595; P:polyamine metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006597; P:spermine biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   SPT12_HUMAN             Reviewed;         190 AA.
AC   Q7Z6I5; A0AVA8; B2RMW1;
DE   RecName: Full=Spermatogenesis-associated protein 12;
DE   AltName: Full=Spermatogenesis-related protein 5;
GN   Name=SPATA12; Synonyms=SRG5;
//
ID   SPT13_HUMAN             Reviewed;         652 AA.
AC   Q96N96; A2VEA9; A6NF85; B4DQB1; B4DSZ0; B4DVM8; J3KPJ7; J3KQH2;
AC   Q5VX68; Q6ZML1; Q8N873; Q8TEK6;
DE   RecName: Full=Spermatogenesis-associated protein 13;
DE   AltName: Full=APC-stimulated guanine nucleotide exchange factor 2;
DE            Short=Asef2;
GN   Name=SPATA13;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IMP:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0043087; P:regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IDA:GOC.
//
ID   SPT16_HUMAN             Reviewed;         569 AA.
AC   Q9BXB7; Q0R0N4; Q0R0S0; Q0R0W2; Q0R129; Q0R131; Q0R140; Q0R1B8;
AC   Q0R1G5; Q0R1I2; Q0R1J6; Q0R1S4; Q0R202; Q0R280; Q0R2F8; Q0R2N6;
AC   Q0R2N7; Q0R2R0; Q0R2R1; Q0R2S3; Q0R2S4; Q0R2S5; Q0R2T4; Q0R2T7;
AC   Q0R2U2; Q0R2U8; Q0R2U9; Q0R2V5; Q0R2V7; Q8NE67;
DE   RecName: Full=Spermatogenesis-associated protein 16;
DE   AltName: Full=Testis development protein NYD-SP12;
GN   Name=SPATA16;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPT17_HUMAN             Reviewed;         361 AA.
AC   Q96L03; A5D6N2;
DE   RecName: Full=Spermatogenesis-associated protein 17;
GN   Name=SPATA17;
//
ID   SPT19_HUMAN             Reviewed;         167 AA.
AC   Q7Z5L4; Q8N7A9;
DE   RecName: Full=Spermatogenesis-associated protein 19, mitochondrial;
DE   AltName: Full=Spermatogenic cell-specific gene 1 protein;
DE            Short=Spergen-1;
DE   Flags: Precursor;
GN   Name=SPATA19; Synonyms=SPERGEN1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPT21_HUMAN             Reviewed;         469 AA.
AC   Q7Z572; B9EK40; F5GXP5;
DE   RecName: Full=Spermatogenesis-associated protein 21;
GN   Name=SPATA21;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   SPT20_HUMAN             Reviewed;         786 AA.
AC   Q8TB22; Q2TA99; Q2XUZ6; Q6P0P1; Q8WVW3; Q9H747;
DE   RecName: Full=Spermatogenesis-associated protein 20;
DE   AltName: Full=Sperm-specific protein 411;
DE            Short=Ssp411;
DE   Flags: Precursor;
GN   Name=SPATA20;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   SPT22_HUMAN             Reviewed;         363 AA.
AC   Q8NHS9; B4DXB1; D3DTI9; J3KN63; Q969H3; Q96JT4;
DE   RecName: Full=Spermatogenesis-associated protein 22;
DE   AltName: Full=Testis development protein NYD-SP20;
GN   Name=SPATA22;
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0000711; P:meiotic DNA repair synthesis; IEA:Ensembl.
DR   GO; GO:0051445; P:regulation of meiotic cell cycle; IEA:Ensembl.
DR   GO; GO:0061458; P:reproductive system development; IEA:Ensembl.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   SPT25_HUMAN             Reviewed;         227 AA.
AC   Q9BR10;
DE   RecName: Full=Spermatogenesis-associated protein 25;
DE   AltName: Full=Testis-specific gene 23 protein;
GN   Name=SPATA25; Synonyms=C20orf165, TSG23;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
//
ID   SPT2_HUMAN              Reviewed;         685 AA.
AC   Q68D10; Q6AWA5; Q6MZI5; Q7Z390; Q7Z470; Q86VG8; Q8N3E7; Q8N417;
AC   Q8N8I3;
DE   RecName: Full=Protein SPT2 homolog;
DE   AltName: Full=Protein KU002155;
DE   AltName: Full=SPT2 domain-containing protein 1;
GN   Name=SPTY2D1;
//
ID   SPT32_HUMAN             Reviewed;         384 AA.
AC   Q96LK8; Q7Z4U1; Q8N6V6;
DE   RecName: Full=Spermatogenesis-associated protein 32;
DE   AltName: Full=Testis-expressed sequence 34 protein;
GN   Name=SPATA32; Synonyms=C17orf46, TEX34;
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   SPT33_HUMAN             Reviewed;         139 AA.
AC   Q96N06; A8WFL2; B4DZN8;
DE   RecName: Full=Spermatogenesis-associated protein 33;
GN   Name=SPATA33; Synonyms=C16orf55;
//
ID   SPT45_HUMAN             Reviewed;          98 AA.
AC   Q537H7;
DE   RecName: Full=Spermatogenesis-associated protein 45;
GN   Name=SPATA45; Synonyms=C1orf227; ORFNames=HSD-44, HSD44;
//
ID   SPT4H_HUMAN             Reviewed;         117 AA.
AC   P63272; B2R4X8; D3DTZ4; Q16550; Q62387; Q6ZP89;
DE   RecName: Full=Transcription elongation factor SPT4;
DE            Short=hSPT4;
DE   AltName: Full=DRB sensitivity-inducing factor 14 kDa subunit;
DE            Short=DSIF p14;
DE   AltName: Full=DRB sensitivity-inducing factor small subunit;
DE            Short=DSIF small subunit;
GN   Name=SUPT4H1; Synonyms=SPT4H, SUPT4H;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0032785; P:negative regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   SPT5H_HUMAN             Reviewed;        1087 AA.
AC   O00267; O43279; Q59G52; Q99639;
DE   RecName: Full=Transcription elongation factor SPT5;
DE            Short=hSPT5;
DE   AltName: Full=DRB sensitivity-inducing factor 160 kDa subunit;
DE            Short=DSIF p160;
DE   AltName: Full=DRB sensitivity-inducing factor large subunit;
DE            Short=DSIF large subunit;
DE   AltName: Full=Tat-cotransactivator 1 protein;
DE            Short=Tat-CT1 protein;
GN   Name=SUPT5H; Synonyms=SPT5, SPT5H;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0032785; P:negative regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0010033; P:response to organic substance; TAS:UniProtKB.
DR   GO; GO:0039692; P:single stranded viral RNA replication via double stranded DNA intermediate; NAS:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   SPT6H_HUMAN             Reviewed;        1726 AA.
AC   Q7KZ85; A7E2B4; Q15737; Q6GMQ4; Q7KYW9; Q7LDK4; Q8N526; Q92775;
AC   Q96AH3; Q9BTH9; Q9BTI2;
DE   RecName: Full=Transcription elongation factor SPT6;
DE            Short=hSPT6;
DE   AltName: Full=Histone chaperone suppressor of Ty6;
DE   AltName: Full=Tat-cotransactivator 2 protein;
DE            Short=Tat-CT2 protein;
GN   Name=SUPT6H; Synonyms=KIAA0162, SPT6H;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006338; P:chromatin remodeling; NAS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0061086; P:negative regulation of histone H3-K27 methylation; IMP:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045191; P:regulation of isotype switching; ISS:UniProtKB.
DR   GO; GO:0010793; P:regulation of mRNA export from nucleus; ISS:UniProtKB.
DR   GO; GO:0050684; P:regulation of mRNA processing; ISS:UniProtKB.
DR   GO; GO:0051147; P:regulation of muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SPTA1_HUMAN             Reviewed;        2419 AA.
AC   P02549; Q15514; Q5VYL1; Q5VYL2; Q6LDY5;
DE   RecName: Full=Spectrin alpha chain, erythrocytic 1;
DE   AltName: Full=Erythroid alpha-spectrin;
GN   Name=SPTA1; Synonyms=SPTA;
DR   GO; GO:0051015; F:actin filament binding; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007015; P:actin filament organization; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0002260; P:lymphocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:Ensembl.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
//
ID   SPTA3_HUMAN             Reviewed;         192 AA.
AC   Q8NHX4; Q86WX5; Q8N9Y6;
DE   RecName: Full=Spermatogenesis-associated protein 3;
DE   AltName: Full=Testis and spermatogenesis cell-related protein 1;
DE   AltName: Full=Testis spermatocyte apoptosis-related protein 1;
GN   Name=SPATA3; Synonyms=TSARG1;
//
ID   SPTB1_HUMAN             Reviewed;        2137 AA.
AC   P11277; Q15510; Q15519;
DE   RecName: Full=Spectrin beta chain, erythrocytic;
DE   AltName: Full=Beta-I spectrin;
GN   Name=SPTB; Synonyms=SPTB1;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:Ensembl.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:Ensembl.
//
ID   SPTB2_HUMAN             Reviewed;        2364 AA.
AC   Q01082; B2RP63; O60837; Q16057; Q53R99; Q59ER3; Q8IX99;
DE   RecName: Full=Spectrin beta chain, non-erythrocytic 1;
DE   AltName: Full=Beta-II spectrin;
DE   AltName: Full=Fodrin beta chain;
DE   AltName: Full=Spectrin, non-erythroid beta chain 1;
GN   Name=SPTBN1; Synonyms=SPTB2;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0030506; F:ankyrin binding; IPI:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IMP:BHF-UCL.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:BHF-UCL.
DR   GO; GO:0071709; P:membrane assembly; IMP:BHF-UCL.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:BHF-UCL.
DR   GO; GO:0007009; P:plasma membrane organization; IMP:BHF-UCL.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IEA:Ensembl.
//
ID   SPTC1_HUMAN             Reviewed;         473 AA.
AC   O15269; A8K681; Q5VWB4; Q96IX6;
DE   RecName: Full=Serine palmitoyltransferase 1;
DE            EC=2.3.1.50;
DE   AltName: Full=Long chain base biosynthesis protein 1;
DE            Short=LCB 1;
DE   AltName: Full=Serine-palmitoyl-CoA transferase 1;
DE            Short=SPT 1;
DE            Short=SPT1;
GN   Name=SPTLC1; Synonyms=LCB1;
DR   GuidetoPHARMACOLOGY; 2509; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046511; P:sphinganine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006686; P:sphingomyelin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IEA:Ensembl.
//
ID   SPTC2_HUMAN             Reviewed;         562 AA.
AC   O15270; Q16685;
DE   RecName: Full=Serine palmitoyltransferase 2;
DE            EC=2.3.1.50;
DE   AltName: Full=Long chain base biosynthesis protein 2;
DE            Short=LCB 2;
DE   AltName: Full=Long chain base biosynthesis protein 2a;
DE            Short=LCB2a;
DE   AltName: Full=Serine-palmitoyl-CoA transferase 2;
DE            Short=SPT 2;
GN   Name=SPTLC2; Synonyms=KIAA0526, LCB2;
DR   GuidetoPHARMACOLOGY; 2510; -.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046513; P:ceramide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046511; P:sphinganine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006686; P:sphingomyelin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0046512; P:sphingosine biosynthetic process; IEA:Ensembl.
//
ID   SPTC3_HUMAN             Reviewed;         552 AA.
AC   Q9NUV7; A2A2I4; B9EK64; Q05DQ8; Q5T1U4; Q9H1L1; Q9H1Z0;
DE   RecName: Full=Serine palmitoyltransferase 3;
DE            EC=2.3.1.50;
DE   AltName: Full=Long chain base biosynthesis protein 2b;
DE            Short=LCB2b;
DE   AltName: Full=Long chain base biosynthesis protein 3;
DE            Short=LCB 3;
DE   AltName: Full=Serine-palmitoyl-CoA transferase 3;
DE            Short=SPT 3;
GN   Name=SPTLC3; Synonyms=C20orf38, SPTLC2L;
DR   GuidetoPHARMACOLOGY; 2511; -.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046520; P:sphingoid biosynthetic process; IDA:MGI.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   SPTCS_HUMAN             Reviewed;        2443 AA.
AC   Q96JI7; A8KAX9; B9EK60; F5H3N6; Q4VC11; Q58G86; Q69YG6; Q6NW01;
AC   Q8N270; Q8TBU9; Q9H734;
DE   RecName: Full=Spatacsin;
DE   AltName: Full=Colorectal carcinoma-associated protein;
DE   AltName: Full=Spastic paraplegia 11 protein;
GN   Name=SPG11; Synonyms=KIAA1840;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   SPTN1_HUMAN             Reviewed;        2472 AA.
AC   Q13813; Q13186; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5;
AC   Q9P0V0;
DE   RecName: Full=Spectrin alpha chain, non-erythrocytic 1;
DE   AltName: Full=Alpha-II spectrin;
DE   AltName: Full=Fodrin alpha chain;
DE   AltName: Full=Spectrin, non-erythroid alpha subunit;
GN   Name=SPTAN1; Synonyms=NEAS, SPTA2;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
//
ID   SPTN2_HUMAN             Reviewed;        2390 AA.
AC   O15020; O14872; O14873;
DE   RecName: Full=Spectrin beta chain, non-erythrocytic 2;
DE   AltName: Full=Beta-III spectrin;
DE   AltName: Full=Spinocerebellar ataxia 5 protein;
GN   Name=SPTBN2; Synonyms=KIAA0302, SCA5;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0021692; P:cerebellar Purkinje cell layer morphogenesis; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0007416; P:synapse assembly; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:UniProtKB.
//
ID   SPTN4_HUMAN             Reviewed;        2564 AA.
AC   Q9H254; E9PGQ5; Q9H1K7; Q9H1K8; Q9H1K9; Q9H253; Q9H3G8; Q9HCD0;
DE   RecName: Full=Spectrin beta chain, non-erythrocytic 4;
DE   AltName: Full=Beta-IV spectrin;
DE   AltName: Full=Spectrin, non-erythroid beta chain 3;
GN   Name=SPTBN4; Synonyms=KIAA1642, SPTBN3;
DR   GO; GO:0003779; F:actin binding; TAS:UniProtKB.
DR   GO; GO:0030506; F:ankyrin binding; IDA:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030507; F:spectrin binding; ISS:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007628; P:adult walking behavior; ISS:BHF-UCL.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007409; P:axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0061337; P:cardiac conduction; ISS:BHF-UCL.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; ISS:BHF-UCL.
DR   GO; GO:0045162; P:clustering of voltage-gated sodium channels; ISS:BHF-UCL.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:UniProtKB.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0010459; P:negative regulation of heart rate; ISS:BHF-UCL.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0033135; P:regulation of peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0002028; P:regulation of sodium ion transport; ISS:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; ISS:BHF-UCL.
DR   GO; GO:0019226; P:transmission of nerve impulse; ISS:BHF-UCL.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
//
ID   SPTN5_HUMAN             Reviewed;        3674 AA.
AC   Q9NRC6;
DE   RecName: Full=Spectrin beta chain, non-erythrocytic 5;
DE   AltName: Full=Beta-V spectrin;
GN   Name=SPTBN5; Synonyms=BSPECV, HUBSPECV, HUSPECV;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0034452; F:dynactin binding; IDA:MGI.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IDA:MGI.
DR   GO; GO:0019894; F:kinesin binding; IDA:MGI.
DR   GO; GO:0032029; F:myosin tail binding; IDA:MGI.
DR   GO; GO:0043621; F:protein self-association; IDA:MGI.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007030; P:Golgi organization; IMP:MGI.
DR   GO; GO:0007041; P:lysosomal transport; IMP:MGI.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:MGI.
//
ID   SPTSA_HUMAN             Reviewed;          71 AA.
AC   Q969W0; B2RD54; D3DS93; Q8WTZ7;
DE   RecName: Full=Serine palmitoyltransferase small subunit A;
DE   AltName: Full=Small subunit of serine palmitoyltransferase A;
DE            Short=ssSPTa;
GN   Name=SPTSSA; Synonyms=C14orf147, SSSPTA;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:UniProtKB.
//
ID   SPTSB_HUMAN             Reviewed;          76 AA.
AC   Q8NFR3; B2R5D3; D3DNM8; Q0P5S6;
DE   RecName: Full=Serine palmitoyltransferase small subunit B;
DE   AltName: Full=Protein ADMP;
DE   AltName: Full=Small subunit of serine palmitoyltransferase B;
DE            Short=ssSPTb;
GN   Name=SPTSSB; Synonyms=ADMP, C3orf57, SSSPTB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:UniProtKB.
//
ID   SPX2_HUMAN              Reviewed;         501 AA.
AC   Q8TED4; A8K2P9; Q6P599; Q7Z7P8; Q8TEM2;
DE   RecName: Full=Sugar phosphate exchanger 2;
DE   AltName: Full=Solute carrier family 37 member 2;
GN   Name=SLC37A2; Synonyms=SPX2;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SPX3_HUMAN              Reviewed;         494 AA.
AC   Q8NCC5; Q6PIU7; Q86SS4; Q9BQG7;
DE   RecName: Full=Sugar phosphate exchanger 3;
DE   AltName: Full=Solute carrier family 37 member 3;
GN   Name=SLC37A3; Synonyms=SPX3;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
//
ID   SPXN1_HUMAN             Reviewed;          72 AA.
AC   Q5VSR9;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome N1;
DE   AltName: Full=Nuclear-associated protein SPAN-Xn1;
DE            Short=SPANX-N1;
DE   AltName: Full=SPANX family member N1;
GN   Name=SPANXN1;
//
ID   SPXN2_HUMAN             Reviewed;         180 AA.
AC   Q5MJ10; Q0ZNM2;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome N2;
DE   AltName: Full=Nuclear-associated protein SPAN-Xn2;
DE            Short=SPANX-N2;
DE   AltName: Full=SPANX family member N2;
GN   Name=SPANXN2;
//
ID   SPXN3_HUMAN             Reviewed;         141 AA.
AC   Q5MJ09; Q0ZNK4;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome N3;
DE   AltName: Full=Nuclear-associated protein SPAN-Xn3;
DE            Short=SPANX-N3;
DE   AltName: Full=SPANX family member N3;
GN   Name=SPANXN3;
//
ID   SPXN4_HUMAN             Reviewed;          99 AA.
AC   Q5MJ08; Q0ZNK6; Q5W0S6;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome N4;
DE   AltName: Full=Nuclear-associated protein SPAN-Xn4;
DE            Short=SPANX-N4;
DE   AltName: Full=SPANX family member N4;
GN   Name=SPANXN4;
//
ID   SPXN5_HUMAN             Reviewed;          72 AA.
AC   Q5MJ07;
DE   RecName: Full=Sperm protein associated with the nucleus on the X chromosome N5;
DE   AltName: Full=Nuclear-associated protein SPAN-Xn5;
DE            Short=SPANX-N5;
DE   AltName: Full=SPANX family member N5;
GN   Name=SPANXN5;
//
ID   SPXN_HUMAN              Reviewed;         116 AA.
AC   Q9BT56; B3KND6;
DE   RecName: Full=Spexin;
DE   AltName: Full=NPQ;
DE   Flags: Precursor;
GN   Name=C12orf39;
//
ID   SPY1_HUMAN              Reviewed;         319 AA.
AC   O43609; D3DNX6; Q6PNE0;
DE   RecName: Full=Protein sprouty homolog 1;
DE            Short=Spry-1;
GN   Name=SPRY1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0051387; P:negative regulation of neurotrophin TRK receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0034261; P:negative regulation of Ras GTPase activity; IEA:Ensembl.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0001759; P:organ induction; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
//
ID   SPY4_HUMAN              Reviewed;         299 AA.
AC   Q9C004; A4FVB2; A4FVB3; Q6QIX2; Q9C003;
DE   RecName: Full=Protein sprouty homolog 4;
DE            Short=Spry-4;
GN   Name=SPRY4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
//
ID   SPY2_HUMAN              Reviewed;         315 AA.
AC   O43597; B2R9J9; Q5T6Z7;
DE   RecName: Full=Protein sprouty homolog 2;
DE            Short=Spry-2;
GN   Name=SPRY2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IMP:UniProtKB.
DR   GO; GO:0030291; F:protein serine/threonine kinase inhibitor activity; IC:BHF-UCL.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060437; P:lung growth; IEA:Ensembl.
DR   GO; GO:0060425; P:lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0051387; P:negative regulation of neurotrophin TRK receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010801; P:negative regulation of peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0034261; P:negative regulation of Ras GTPase activity; IEA:Ensembl.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:GOC.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   SPY3_HUMAN              Reviewed;         288 AA.
AC   O43610; A8K0H8;
DE   RecName: Full=Protein sprouty homolog 3;
DE            Short=Spry-3;
GN   Name=SPRY3;
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
//
ID   SPYA_HUMAN              Reviewed;         392 AA.
AC   P21549; Q53QU6;
DE   RecName: Full=Serine--pyruvate aminotransferase;
DE            Short=SPT;
DE            EC=2.6.1.51;
DE   AltName: Full=Alanine--glyoxylate aminotransferase;
DE            Short=AGT;
DE            EC=2.6.1.44;
GN   Name=AGXT; Synonyms=AGT1, SPAT;
DR   GO; GO:0008453; F:alanine-glyoxylate transaminase activity; IDA:UniProtKB.
DR   GO; GO:0016597; F:amino acid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0004760; F:serine-pyruvate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008483; F:transaminase activity; IDA:UniProtKB.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0019265; P:glycine biosynthetic process, by transamination of glyoxylate; IDA:UniProtKB.
DR   GO; GO:0009436; P:glyoxylate catabolic process; IDA:UniProtKB.
DR   GO; GO:0046487; P:glyoxylate metabolic process; IMP:HGNC.
DR   GO; GO:0042853; P:L-alanine catabolic process; IDA:UniProtKB.
DR   GO; GO:0019448; P:L-cysteine catabolic process; IDA:UniProtKB.
DR   GO; GO:0046724; P:oxalic acid secretion; IEA:Ensembl.
DR   GO; GO:0006625; P:protein targeting to peroxisome; IMP:HGNC.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SPZ1_HUMAN              Reviewed;         430 AA.
AC   Q9BXG8; B2RA21; Q8N4P1; Q8N7E9;
DE   RecName: Full=Spermatogenic leucine zipper protein 1;
DE   AltName: Full=Testis-specific protein 1;
DE   AltName: Full=Testis-specific protein NYD-TSP1;
GN   Name=SPZ1; Synonyms=TSP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SQRD_HUMAN              Reviewed;         450 AA.
AC   Q9Y6N5; Q9UQM8;
DE   RecName: Full=Sulfide:quinone oxidoreductase, mitochondrial;
DE            EC=1.-.-.-;
DE   Flags: Precursor;
GN   Name=SQRDL; ORFNames=CGI-44;
DR   GO; GO:0070224; F:sulfide:quinone oxidoreductase activity; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   SQSTM_HUMAN             Reviewed;         440 AA.
AC   Q13501; A6NFN7; B2R661; B3KUW5; Q13446; Q9BUV7; Q9BVS6; Q9UEU1;
DE   RecName: Full=Sequestosome-1;
DE   AltName: Full=EBI3-associated protein of 60 kDa;
DE            Short=EBIAP;
DE            Short=p60;
DE   AltName: Full=Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa;
DE   AltName: Full=Ubiquitin-binding protein p62;
GN   Name=SQSTM1; Synonyms=ORCA, OSIL;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; TAS:ProtInc.
DR   GO; GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; TAS:UniProtKB.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:UniProtKB.
DR   GO; GO:0016236; P:macroautophagy; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; TAS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:GOC.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0046578; P:regulation of Ras protein signal transduction; NAS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   SR140_HUMAN             Reviewed;        1029 AA.
AC   O15042; A0PJ60; Q0D2M1; Q2NKQ7; Q9BR70;
DE   RecName: Full=U2 snRNP-associated SURP motif-containing protein;
DE   AltName: Full=140 kDa Ser/Arg-rich domain protein;
DE   AltName: Full=U2-associated protein SR140;
GN   Name=U2SURP; Synonyms=KIAA0332, SR140;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   SR1IP_HUMAN             Reviewed;         155 AA.
AC   Q8N9Q2; Q32NC8;
DE   RecName: Full=Protein SREK1IP1;
DE   AltName: Full=SFRS12-interacting protein 1;
DE   AltName: Full=SREK1-interacting protein 1;
DE   AltName: Full=Splicing regulatory protein of 18 kDa;
DE            Short=p18SRP;
GN   Name=SREK1IP1; Synonyms=P18SRP, SFRS12IP1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SRA1_HUMAN              Reviewed;         236 AA.
AC   Q9HD15; Q6NVU9; Q8IXM1; Q9HD13; Q9HD14;
DE   RecName: Full=Steroid receptor RNA activator 1;
DE   AltName: Full=Steroid receptor RNA activator protein;
DE            Short=SRAP;
GN   Name=SRA1; ORFNames=PP7684;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010861; F:thyroid hormone receptor activator activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000273; P:positive regulation of receptor activity; IBA:RefGenome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRAC1_HUMAN             Reviewed;         654 AA.
AC   Q96JX3; Q49AT1; Q5VTX3; Q6PKF3;
DE   RecName: Full=Protein SERAC1;
DE   AltName: Full=Serine active site-containing protein 1;
GN   Name=SERAC1;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0006505; P:GPI anchor metabolic process; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
//
ID   SRB4D_HUMAN             Reviewed;         575 AA.
AC   Q8WTU2; Q2HIZ5; Q6ZMG3; Q96BF5;
DE   RecName: Full=Scavenger receptor cysteine-rich domain-containing group B protein;
DE   AltName: Full=S4-SRCRB;
DE   Flags: Precursor;
GN   Name=SRCRB4D;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
//
ID   SRBD1_HUMAN             Reviewed;         995 AA.
AC   Q8N5C6; Q53T56; Q96TA4; Q9NW11;
DE   RecName: Full=S1 RNA-binding domain-containing protein 1;
GN   Name=SRBD1;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
//
ID   SRBP1_HUMAN             Reviewed;        1147 AA.
AC   P36956; B0I4X3; B0I4X4; D3DXC4; Q16062; Q59F52; Q6P4R7; Q6PFW7;
AC   Q6PJ36; Q8TAK9;
DE   RecName: Full=Sterol regulatory element-binding protein 1;
DE            Short=SREBP-1;
DE   AltName: Full=Class D basic helix-loop-helix protein 1;
DE            Short=bHLHd1;
DE   AltName: Full=Sterol regulatory element-binding transcription factor 1;
DE   Contains:
DE     RecName: Full=Processed sterol regulatory element-binding protein 1;
GN   Name=SREBF1; Synonyms=BHLHD1, SREBP1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:HGNC.
DR   GO; GO:0032810; F:sterol response element binding; IDA:HGNC.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; ISS:HGNC.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008610; P:lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045542; P:positive regulation of cholesterol biosynthetic process; IEA:Ensembl.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0019217; P:regulation of fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0003062; P:regulation of heart rate by chemical signal; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032094; P:response to food; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRBP2_HUMAN             Reviewed;        1141 AA.
AC   Q12772; Q05BD5; Q6GTH7; Q86V36; Q9UH04;
DE   RecName: Full=Sterol regulatory element-binding protein 2;
DE            Short=SREBP-2;
DE   AltName: Full=Class D basic helix-loop-helix protein 2;
DE            Short=bHLHd2;
DE   AltName: Full=Sterol regulatory element-binding transcription factor 2;
DE   Contains:
DE     RecName: Full=Processed sterol regulatory element-binding protein 2;
GN   Name=SREBF2; Synonyms=BHLHD2, SREBP2;
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071499; P:cellular response to laminar fluid shear stress; NAS:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0090370; P:negative regulation of cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0010886; P:positive regulation of cholesterol storage; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000188; P:regulation of cholesterol homeostasis; IEA:Ensembl.
DR   GO; GO:0072368; P:regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0055098; P:response to low-density lipoprotein particle; IEP:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRBS1_HUMAN             Reviewed;        1292 AA.
AC   Q9BX66; A0AED4; A6NEK3; A6NID8; A6NJS4; A7MD40; D3DR42; O43857;
AC   Q5T923; Q5T924; Q5T927; Q5T928; Q5T929; Q5T930; Q5T931; Q5T932;
AC   Q7LBE5; Q8IVK0; Q8IVQ4; Q96KF3; Q96KF4; Q9BX64; Q9BX65; Q9P2Q0;
AC   Q9UFT2; Q9UHN7; Q9Y338;
DE   RecName: Full=Sorbin and SH3 domain-containing protein 1;
DE   AltName: Full=Ponsin;
DE   AltName: Full=SH3 domain protein 5;
DE   AltName: Full=SH3P12;
DE   AltName: Full=c-Cbl-associated protein;
DE            Short=CAP;
GN   Name=SORBS1; Synonyms=KIAA0894, KIAA1296, SH3D5;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0008092; F:cytoskeletal protein binding; TAS:ProtInc.
DR   GO; GO:0005158; F:insulin receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; ISS:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.
DR   GO; GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0015758; P:glucose transport; ISS:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; ISS:BHF-UCL.
DR   GO; GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.
DR   GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0009967; P:positive regulation of signal transduction; ISS:GOC.
DR   GO; GO:0043149; P:stress fiber assembly; ISS:UniProtKB.
//
ID   SRBS2_HUMAN             Reviewed;        1100 AA.
AC   O94875; A6NEK9; B3KPQ7; B7Z1G5; B7Z3X6; C9JKV9; D3DP62; D3DP63;
AC   E9PAS5; E9PAW4; G3XAI0; H7BXR4; J3KNZ5; O60592; O60593; Q96EX0;
DE   RecName: Full=Sorbin and SH3 domain-containing protein 2;
DE   AltName: Full=Arg/Abl-interacting protein 2;
DE            Short=ArgBP2;
DE   AltName: Full=Sorbin;
GN   Name=SORBS2; Synonyms=ARGBP2, KIAA0777;
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
//
ID   SRC8_HUMAN              Reviewed;         550 AA.
AC   Q14247; Q8N707; Q96H99;
DE   RecName: Full=Src substrate cortactin;
DE   AltName: Full=Amplaxin;
DE   AltName: Full=Oncogene EMS1;
GN   Name=CTTN; Synonyms=EMS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   SRCH_HUMAN              Reviewed;         699 AA.
AC   P23327; Q504Y6;
DE   RecName: Full=Sarcoplasmic reticulum histidine-rich calcium-binding protein;
DE   Flags: Precursor;
GN   Name=HRC; Synonyms=HCP;
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; TAS:BHF-UCL.
//
ID   SRCAP_HUMAN             Reviewed;        3230 AA.
AC   Q6ZRS2; B0JZA6; O15026; Q7Z744; Q9Y5L9;
DE   RecName: Full=Helicase SRCAP;
DE            EC=3.6.4.-;
DE   AltName: Full=Domino homolog 2;
DE   AltName: Full=Snf2-related CBP activator;
GN   Name=SRCAP; Synonyms=KIAA0309;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004402; F:histone acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0016573; P:histone acetylation; TAS:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SRCA_HUMAN              Reviewed;         932 AA.
AC   Q86TD4;
DE   RecName: Full=Sarcalumenin;
DE   Flags: Precursor;
GN   Name=SRL;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
//
ID   SRCN1_HUMAN             Reviewed;        1055 AA.
AC   Q9C0H9; Q75T46; Q8N4W8;
DE   RecName: Full=SRC kinase signaling inhibitor 1;
DE   AltName: Full=SNAP-25-interacting protein;
DE            Short=SNIP;
DE   AltName: Full=p130Cas-associated protein;
DE   AltName: Full=p140Cap;
GN   Name=SRCIN1; Synonyms=KIAA1684, P140;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0061099; P:negative regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0061001; P:regulation of dendritic spine morphogenesis; IMP:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
//
ID   SRCRL_HUMAN             Reviewed;        1573 AA.
AC   A1L4H1; B5MDQ5; C7S7T9; C7S7U0; K7EP70;
DE   RecName: Full=Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D;
DE   AltName: Full=Soluble scavenger protein with 5 SRCR domains;
DE            Short=SSc5D;
DE   Flags: Precursor;
GN   Name=SSC5D;
DR   GO; GO:0050840; F:extracellular matrix binding; ISS:UniProtKB.
DR   GO; GO:0001968; F:fibronectin binding; ISS:UniProtKB.
DR   GO; GO:0043236; F:laminin binding; ISS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0042494; P:detection of bacterial lipoprotein; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:2000483; P:negative regulation of interleukin-8 secretion; ISS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; ISS:GOC.
//
ID   SRCRM_HUMAN             Reviewed;        1027 AA.
AC   Q4G0T1; C9K0L3;
DE   RecName: Full=Scavenger receptor cysteine-rich domain-containing protein SCART1;
DE   Flags: Precursor;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   SRC_HUMAN               Reviewed;         536 AA.
AC   P12931; E1P5V4; Q76P87; Q86VB9; Q9H5A8;
DE   RecName: Full=Proto-oncogene tyrosine-protein kinase Src;
DE            EC=2.7.10.2;
DE   AltName: Full=Proto-oncogene c-Src;
DE   AltName: Full=pp60c-src;
DE            Short=p60-Src;
GN   Name=SRC; Synonyms=SRC1;
DR   GuidetoPHARMACOLOGY; 2206; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.
DR   GO; GO:0070851; F:growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0020037; F:heme binding; IDA:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; TAS:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0016301; F:kinase activity; TAS:Reactome.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0042169; F:SH2 domain binding; IPI:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; ISS:UniProtKB.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071393; P:cellular response to progesterone stimulus; ISS:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:BHF-UCL.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; ISS:BHF-UCL.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0051902; P:negative regulation of mitochondrial depolarization; IMP:UniProtKB.
DR   GO; GO:0032463; P:negative regulation of protein homooligomerization; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048477; P:oogenesis; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0033625; P:positive regulation of integrin activation; TAS:BHF-UCL.
DR   GO; GO:0071803; P:positive regulation of podosome assembly; IEA:Ensembl.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0050847; P:progesterone receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; TAS:Reactome.
DR   GO; GO:0045124; P:regulation of bone resorption; TAS:BHF-UCL.
DR   GO; GO:0033146; P:regulation of intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0007172; P:signal complex assembly; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0060065; P:uterus development; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SREC2_HUMAN             Reviewed;         870 AA.
AC   Q96GP6; E5RFB8; Q58A83; Q8IXF3; Q9BW74;
DE   RecName: Full=Scavenger receptor class F member 2;
DE   AltName: Full=SRECRP-1;
DE   AltName: Full=Scavenger receptor expressed by endothelial cells 2 protein;
DE            Short=SREC-II;
DE   Flags: Precursor;
GN   Name=SCARF2; Synonyms=SREC2, SREPCR;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:Ensembl.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IEA:Ensembl.
//
ID   SREC_HUMAN              Reviewed;         830 AA.
AC   Q14162; A8MQ05; O43701; Q8NHD2; Q8NHD3; Q8NHD4; Q8NHD5;
DE   RecName: Full=Scavenger receptor class F member 1;
DE   AltName: Full=Acetyl LDL receptor;
DE   AltName: Full=Scavenger receptor expressed by endothelial cells 1;
DE            Short=SREC-I;
DE   Flags: Precursor;
GN   Name=SCARF1; Synonyms=KIAA0149, SREC;
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IDA:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006707; P:cholesterol catabolic process; IC:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0016322; P:neuron remodeling; ISS:UniProtKB.
DR   GO; GO:0048680; P:positive regulation of axon regeneration; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   SREK1_HUMAN             Reviewed;         508 AA.
AC   Q8WXA9; A4FTW3; Q2M1J0; Q86X37;
DE   RecName: Full=Splicing regulatory glutamine/lysine-rich protein 1;
DE   AltName: Full=Serine/arginine-rich-splicing regulatory protein 86;
DE            Short=SRrp86;
DE   AltName: Full=Splicing factor, arginine/serine-rich 12;
DE   AltName: Full=Splicing regulatory protein 508;
DE            Short=SRrp508;
GN   Name=SREK1; Synonyms=SFRS12, SRRP86;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SRFB1_HUMAN             Reviewed;         429 AA.
AC   Q8NEF9; Q5QFI2; Q96AH4; Q96DK2;
DE   RecName: Full=Serum response factor-binding protein 1;
DE   AltName: Full=SRF-dependent transcription regulation-associated protein;
DE   AltName: Full=p49/STRAP;
GN   Name=SRFBP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRF_HUMAN               Reviewed;         508 AA.
AC   P11831; Q5T648;
DE   RecName: Full=Serum response factor;
DE            Short=SRF;
GN   Name=SRF;
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0010736; F:serum response element binding; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0060055; P:angiogenesis involved in wound healing; TAS:BHF-UCL.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0055003; P:cardiac myofibril assembly; IEA:Ensembl.
DR   GO; GO:0060947; P:cardiac vascular smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0090398; P:cellular senescence; IMP:BHF-UCL.
DR   GO; GO:0030038; P:contractile actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0035912; P:dorsal aorta morphogenesis; IEA:Ensembl.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0010669; P:epithelial structure maintenance; IEA:Ensembl.
DR   GO; GO:0048821; P:erythrocyte development; IEA:Ensembl.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0060347; P:heart trabecula formation; IEA:Ensembl.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Ensembl.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0046716; P:muscle cell cellular homeostasis; ISS:BHF-UCL.
DR   GO; GO:1900222; P:negative regulation of beta-amyloid clearance; IMP:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; TAS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0030220; P:platelet formation; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IDA:MGI.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IDA:BHF-UCL.
DR   GO; GO:0046016; P:positive regulation of transcription by glucose; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0003257; P:positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; IGI:BHF-UCL.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0010735; P:positive regulation of transcription via serum response element binding; IDA:BHF-UCL.
DR   GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0051150; P:regulation of smooth muscle cell differentiation; TAS:BHF-UCL.
DR   GO; GO:0033561; P:regulation of water loss via skin; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IMP:BHF-UCL.
DR   GO; GO:0009725; P:response to hormone; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEP:BHF-UCL.
DR   GO; GO:0009636; P:response to toxic substance; TAS:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0043589; P:skin morphogenesis; IEA:Ensembl.
DR   GO; GO:0043149; P:stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0001829; P:trophectodermal cell differentiation; IDA:MGI.
//
ID   SRG2C_HUMAN             Reviewed;         459 AA.
AC   P0DJJ0;
DE   RecName: Full=SLIT-ROBO Rho GTPase-activating protein 2C;
DE   AltName: Full=SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1;
GN   Name=SRGAP2C; Synonyms=SRGAP2P1;
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0021816; P:extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration; IDA:UniProtKB.
DR   GO; GO:0061000; P:negative regulation of dendritic spine development; IDA:UniProtKB.
DR   GO; GO:0051490; P:negative regulation of filopodium assembly; IDA:UniProtKB.
DR   GO; GO:2001224; P:positive regulation of neuron migration; IDA:UniProtKB.
//
ID   SRGEF_HUMAN             Reviewed;         458 AA.
AC   Q9UGK8; Q9UGK9;
DE   RecName: Full=Secretion-regulating guanine nucleotide exchange factor;
DE   AltName: Full=Deafness locus-associated putative guanine nucleotide exchange factor;
DE            Short=DelGEF;
DE   AltName: Full=Guanine nucleotide exchange factor-related protein;
GN   Name=SERGEF; Synonyms=DELGEF, GNEFR;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
DR   GO; GO:0050709; P:negative regulation of protein secretion; IDA:HGNC.
DR   GO; GO:0032316; P:regulation of Ran GTPase activity; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
//
ID   SRGN_HUMAN              Reviewed;         158 AA.
AC   P10124; B2R4L7; Q5VW06;
DE   RecName: Full=Serglycin;
DE   AltName: Full=Hematopoietic proteoglycan core protein;
DE   AltName: Full=Platelet proteoglycan core protein;
DE            Short=P.PG;
DE   AltName: Full=Secretory granule proteoglycan core protein;
DE   Flags: Precursor;
GN   Name=SRGN; Synonyms=PRG, PRG1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008626; P:granzyme-mediated apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0033382; P:maintenance of granzyme B location in T cell secretory granule; ISS:UniProtKB.
DR   GO; GO:0033373; P:maintenance of protease location in mast cell secretory granule; ISS:UniProtKB.
DR   GO; GO:0033364; P:mast cell secretory granule organization; ISS:UniProtKB.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; IDA:UniProtKB.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; ISS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0016485; P:protein processing; ISS:UniProtKB.
DR   GO; GO:0033371; P:T cell secretory granule organization; ISS:UniProtKB.
//
ID   SRGP1_HUMAN             Reviewed;        1085 AA.
AC   Q7Z6B7; Q9H8A3; Q9P2P2;
DE   RecName: Full=SLIT-ROBO Rho GTPase-activating protein 1;
DE            Short=srGAP1;
DE   AltName: Full=Rho GTPase-activating protein 13;
GN   Name=SRGAP1; Synonyms=ARHGAP13, KIAA1304;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005100; F:Rho GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   SRGP2_HUMAN             Reviewed;        1071 AA.
AC   O75044;
DE   RecName: Full=SLIT-ROBO Rho GTPase-activating protein 2;
DE            Short=srGAP2;
DE   AltName: Full=Formin-binding protein 2;
DE   AltName: Full=Rho GTPase-activating protein 34;
GN   Name=SRGAP2; Synonyms=ARHGAP34, FNBP2, KIAA0456, SRGAP2A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0048365; F:Rac GTPase binding; IDA:UniProtKB.
DR   GO; GO:0051014; P:actin filament severing; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0060996; P:dendritic spine development; IDA:UniProtKB.
DR   GO; GO:0021816; P:extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration; ISS:UniProtKB.
DR   GO; GO:0046847; P:filopodium assembly; IDA:UniProtKB.
DR   GO; GO:0003363; P:lamellipodium assembly involved in ameboidal cell migration; IMP:UniProtKB.
DR   GO; GO:2001223; P:negative regulation of neuron migration; IDA:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IDA:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
//
ID   SRGP3_HUMAN             Reviewed;        1099 AA.
AC   O43295; Q8IX13; Q8IZV8;
DE   RecName: Full=SLIT-ROBO Rho GTPase-activating protein 3;
DE            Short=srGAP3;
DE   AltName: Full=Mental disorder-associated GAP;
DE   AltName: Full=Rho GTPase-activating protein 14;
DE   AltName: Full=WAVE-associated Rac GTPase-activating protein;
DE            Short=WRP;
GN   Name=SRGAP3; Synonyms=ARHGAP14, KIAA0411, KIAA1156, MEGAP, SRGAP2;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   SRMS_HUMAN              Reviewed;         488 AA.
AC   Q9H3Y6;
DE   RecName: Full=Tyrosine-protein kinase Srms;
DE            EC=2.7.10.2;
GN   Name=SRMS; Synonyms=C20orf148;
DR   GuidetoPHARMACOLOGY; 2207; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0038083; P:peptidyl-tyrosine autophosphorylation; IDA:UniProtKB.
//
ID   SRP09_HUMAN             Reviewed;          86 AA.
AC   P49458; A8K0N0; Q6NVX0; Q8WTW0;
DE   RecName: Full=Signal recognition particle 9 kDa protein;
DE            Short=SRP9;
GN   Name=SRP9;
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0005047; F:signal recognition particle binding; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045900; P:negative regulation of translational elongation; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRP14_HUMAN             Reviewed;         136 AA.
AC   P37108; B5BUF5; Q6B0K5; Q96Q14;
DE   RecName: Full=Signal recognition particle 14 kDa protein;
DE            Short=SRP14;
DE   AltName: Full=18 kDa Alu RNA-binding protein;
GN   Name=SRP14;
DR   GO; GO:0008312; F:7S RNA binding; TAS:ProtInc.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045047; P:protein targeting to ER; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRP19_HUMAN             Reviewed;         144 AA.
AC   P09132; B2R4E9; D6RCQ5; Q05D77; Q96FG6;
DE   RecName: Full=Signal recognition particle 19 kDa protein;
DE            Short=SRP19;
GN   Name=SRP19;
DR   GO; GO:0008312; F:7S RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRP54_HUMAN             Reviewed;         504 AA.
AC   P61011; B2R759; B4DUW6; P13624;
DE   RecName: Full=Signal recognition particle 54 kDa protein;
DE            Short=SRP54;
GN   Name=SRP54;
DR   GO; GO:0008312; F:7S RNA binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IDA:UniProtKB.
DR   GO; GO:0019003; F:GDP binding; IDA:UniProtKB.
DR   GO; GO:0005525; F:GTP binding; IDA:UniProtKB.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:MGI.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0045047; P:protein targeting to ER; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006617; P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition; ISS:UniProtKB.
DR   GO; GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRP68_HUMAN             Reviewed;         627 AA.
AC   Q9UHB9; B3KUU5; B3KWY7; G3V1U4; Q8NCJ4; Q8WUK2;
DE   RecName: Full=Signal recognition particle subunit SRP68;
DE            Short=SRP68;
DE   AltName: Full=Signal recognition particle 68 kDa protein;
GN   Name=SRP68;
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0030942; F:endoplasmic reticulum signal peptide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005047; F:signal recognition particle binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRP72_HUMAN             Reviewed;         671 AA.
AC   O76094; G5E9Z8; Q7Z3C0;
DE   RecName: Full=Signal recognition particle subunit SRP72;
DE            Short=SRP72;
DE   AltName: Full=Signal recognition particle 72 kDa protein;
GN   Name=SRP72;
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005047; F:signal recognition particle binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRPK1_HUMAN             Reviewed;         655 AA.
AC   Q96SB4; Q12890; Q5R364; Q5R365; Q8IY12;
DE   RecName: Full=SRSF protein kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=SFRS protein kinase 1;
DE   AltName: Full=Serine/arginine-rich protein-specific kinase 1;
DE            Short=SR-protein-specific kinase 1;
GN   Name=SRPK1;
DR   GuidetoPHARMACOLOGY; 2208; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IC:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050684; P:regulation of mRNA processing; IDA:UniProtKB.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; TAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0035092; P:sperm chromatin condensation; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SRPK2_HUMAN             Reviewed;         688 AA.
AC   P78362; A8MVX2; O75220; O75221; Q6NUL0; Q6V1X2; Q8IYQ3;
DE   RecName: Full=SRSF protein kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=SFRS protein kinase 2;
DE   AltName: Full=Serine/arginine-rich protein-specific kinase 2;
DE            Short=SR-protein-specific kinase 2;
DE   Contains:
DE     RecName: Full=SRSF protein kinase 2 N-terminal;
DE   Contains:
DE     RecName: Full=SRSF protein kinase 2 C-terminal;
GN   Name=SRPK2;
DR   GuidetoPHARMACOLOGY; 2209; -.
DR   GO; GO:0071889; F:14-3-3 protein binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IC:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0035063; P:nuclear speck organization; ISS:BHF-UCL.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:BHF-UCL.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; TAS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IDA:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IDA:UniProtKB.
//
ID   SRPK3_HUMAN             Reviewed;         567 AA.
AC   Q9UPE1; Q13583; Q4F970; Q562F5; Q9UM62;
DE   RecName: Full=SRSF protein kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Muscle-specific serine kinase 1;
DE            Short=MSSK-1;
DE   AltName: Full=Serine/arginine-rich protein-specific kinase 3;
DE            Short=SR-protein-specific kinase 3;
DE   AltName: Full=Serine/threonine-protein kinase 23;
GN   Name=SRPK3; Synonyms=MSSK1, STK23;
DR   GuidetoPHARMACOLOGY; 2210; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0060537; P:muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
//
ID   SRPRB_HUMAN             Reviewed;         271 AA.
AC   Q9Y5M8; Q6P595; Q8N2D8;
DE   RecName: Full=Signal recognition particle receptor subunit beta;
DE            Short=SR-beta;
DE   AltName: Full=Protein APMCF1;
GN   Name=SRPRB; ORFNames=PSEC0230;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRPR_HUMAN              Reviewed;         638 AA.
AC   P08240; A6NIB3; B2R5Z8; B4E0H3; E9PJS4; Q9BVJ4;
DE   RecName: Full=Signal recognition particle receptor subunit alpha;
DE            Short=SR-alpha;
DE   AltName: Full=Docking protein alpha;
DE            Short=DP-alpha;
GN   Name=SRPR;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005047; F:signal recognition particle binding; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SRPX2_HUMAN             Reviewed;         465 AA.
AC   O60687; B3KQT3; Q8WW85;
DE   RecName: Full=Sushi repeat-containing protein SRPX2;
DE   AltName: Full=Sushi-repeat protein upregulated in leukemia;
DE   Flags: Precursor;
GN   Name=SRPX2; Synonyms=SRPUL;
DR   GO; GO:0036458; F:hepatocyte growth factor binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0048870; P:cell motility; IDA:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IDA:UniProtKB.
DR   GO; GO:0042325; P:regulation of phosphorylation; IDA:UniProtKB.
//
ID   SRPX_HUMAN              Reviewed;         464 AA.
AC   P78539; A8K065; B3KWP8; B4DDB8; B4DQH5; F5H4D7; G3V1L0; Q4VX66;
AC   Q99652; Q99913;
DE   RecName: Full=Sushi repeat-containing protein SRPX;
DE   Flags: Precursor;
GN   Name=SRPX; Synonyms=ETX1;
DR   GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IEA:Ensembl.
DR   GO; GO:0001845; P:phagolysosome assembly; IEA:Ensembl.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
//
ID   SRR1L_HUMAN             Reviewed;         339 AA.
AC   Q9UH36; Q6NXP8;
DE   RecName: Full=SRR1-like protein;
DE   AltName: Full=SRR1 domain-containing protein;
GN   Name=SRRD; Synonyms=SRR1L;
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
//
ID   SRRM1_HUMAN             Reviewed;         904 AA.
AC   Q8IYB3; O60585; Q5VVN4;
DE   RecName: Full=Serine/arginine repetitive matrix protein 1;
DE   AltName: Full=SR-related nuclear matrix protein of 160 kDa;
DE            Short=SRm160;
DE   AltName: Full=Ser/Arg-related nuclear matrix protein;
GN   Name=SRRM1; Synonyms=SRM160;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRRM2_HUMAN             Reviewed;        2752 AA.
AC   Q9UQ35; A6NKB9; D3DU97; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40;
AC   Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40;
DE   RecName: Full=Serine/arginine repetitive matrix protein 2;
DE   AltName: Full=300 kDa nuclear matrix antigen;
DE   AltName: Full=Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa;
DE            Short=SR-related nuclear matrix protein of 300 kDa;
DE            Short=Ser/Arg-related nuclear matrix protein of 300 kDa;
DE   AltName: Full=Splicing coactivator subunit SRm300;
DE   AltName: Full=Tax-responsive enhancer element-binding protein 803;
DE            Short=TaxREB803;
GN   Name=SRRM2; Synonyms=KIAA0324, SRL300, SRM300; ORFNames=HSPC075;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   SRRM3_HUMAN             Reviewed;         597 AA.
AC   A6NNA2; A6ND75;
DE   RecName: Full=Serine/arginine repetitive matrix protein 3;
GN   Name=SRRM3;
//
ID   SRRM4_HUMAN             Reviewed;         611 AA.
AC   A7MD48; A8K5P6; B2RZH7; Q7Z5F0; Q96JH4;
DE   RecName: Full=Serine/arginine repetitive matrix protein 4;
DE   AltName: Full=Medulloblastoma antigen MU-MB-2.76;
DE   AltName: Full=Neural-specific serine/arginine repetitive splicing factor of 100 kDa;
DE            Short=Neural-specific SR-related protein of 100 kDa;
DE            Short=nSR100;
GN   Name=SRRM4; Synonyms=KIAA1853;
DR   GO; GO:0003729; F:mRNA binding; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; ISS:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:Ensembl.
DR   GO; GO:0043484; P:regulation of RNA splicing; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   SRRM5_HUMAN             Reviewed;         715 AA.
AC   B3KS81; B4DNF0;
DE   RecName: Full=Serine/arginine repetitive matrix protein 5;
GN   Name=SRRM5; Synonyms=ZNF576;
//
ID   SRRT_HUMAN              Reviewed;         876 AA.
AC   Q9BXP5; A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; O95808; Q32MI4;
AC   Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9Y4S4;
DE   RecName: Full=Serrate RNA effector molecule homolog;
DE   AltName: Full=Arsenite-resistance protein 2;
GN   Name=SRRT; Synonyms=ARS2, ASR2;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0097150; P:neuronal stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0031053; P:primary miRNA processing; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0046685; P:response to arsenic-containing substance; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRR_HUMAN               Reviewed;         340 AA.
AC   Q9GZT4; D3DTI5; Q6IA55;
DE   RecName: Full=Serine racemase;
DE            EC=4.3.1.17;
DE            EC=4.3.1.18;
DE            EC=5.1.1.18;
DE   AltName: Full=D-serine ammonia-lyase;
DE   AltName: Full=D-serine dehydratase;
DE   AltName: Full=L-serine ammonia-lyase;
DE   AltName: Full=L-serine dehydratase;
GN   Name=SRR;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB.
DR   GO; GO:0008721; F:D-serine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016594; F:glycine binding; ISS:UniProtKB.
DR   GO; GO:0003941; F:L-serine ammonia-lyase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.
DR   GO; GO:0030378; F:serine racemase activity; IDA:UniProtKB.
DR   GO; GO:0018114; F:threonine racemase activity; ISS:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0070179; P:D-serine biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0070178; P:D-serine metabolic process; IDA:UniProtKB.
DR   GO; GO:0006563; P:L-serine metabolic process; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0009069; P:serine family amino acid metabolic process; ISS:UniProtKB.
//
ID   SRS10_HUMAN             Reviewed;         262 AA.
AC   O75494; A6NFM6; A6NI42; A6NIU7; B4DJP9; O60572; Q5JRH9; Q5JRI0;
AC   Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17;
DE   RecName: Full=Serine/arginine-rich splicing factor 10;
DE   AltName: Full=40 kDa SR-repressor protein;
DE            Short=SRrp40;
DE   AltName: Full=FUS-interacting serine-arginine-rich protein 1;
DE   AltName: Full=Splicing factor SRp38;
DE   AltName: Full=Splicing factor, arginine/serine-rich 13A;
DE   AltName: Full=TLS-associated protein with Ser-Arg repeats;
DE            Short=TASR;
DE            Short=TLS-associated protein with SR repeats;
DE   AltName: Full=TLS-associated serine-arginine protein;
DE            Short=TLS-associated SR protein;
GN   Name=SRSF10; Synonyms=FUSIP1, FUSIP2, SFRS13A, TASR;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0050733; F:RS domain binding; NAS:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0016482; P:cytoplasmic transport; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; NAS:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; IDA:UniProtKB.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; NAS:UniProtKB.
//
ID   SRS11_HUMAN             Reviewed;         484 AA.
AC   Q05519; Q5T758; Q8IWE6;
DE   RecName: Full=Serine/arginine-rich splicing factor 11;
DE   AltName: Full=Arginine-rich 54 kDa nuclear protein;
DE            Short=p54;
DE   AltName: Full=Splicing factor, arginine/serine-rich 11;
GN   Name=SRSF11; Synonyms=SFRS11;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRS12_HUMAN             Reviewed;         261 AA.
AC   Q8WXF0; B2RA22; Q5T7K0; Q8WW25;
DE   RecName: Full=Serine/arginine-rich splicing factor 12;
DE   AltName: Full=35 kDa SR repressor protein;
DE            Short=SRrp35;
DE   AltName: Full=Splicing factor, arginine/serine-rich 13B;
DE   AltName: Full=Splicing factor, arginine/serine-rich 19;
GN   Name=SRSF12; Synonyms=SFRS13B, SFRS19, SRRP35;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; NAS:UniProtKB.
DR   GO; GO:0050733; F:RS domain binding; NAS:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0016482; P:cytoplasmic transport; ISS:UniProtKB.
DR   GO; GO:0000395; P:mRNA 5'-splice site recognition; IDA:UniProtKB.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; NAS:UniProtKB.
//
ID   SRSF1_HUMAN             Reviewed;         248 AA.
AC   Q07955; B2R6Z7; D3DTZ3; Q13809;
DE   RecName: Full=Serine/arginine-rich splicing factor 1;
DE   AltName: Full=Alternative-splicing factor 1;
DE            Short=ASF-1;
DE   AltName: Full=Splicing factor, arginine/serine-rich 1;
DE   AltName: Full=pre-mRNA-splicing factor SF2, P33 subunit;
GN   Name=SRSF1; Synonyms=ASF, SF2, SF2P33, SFRS1; ORFNames=OK/SW-cl.3;
DR   GO; GO:0003729; F:mRNA binding; IDA:MGI.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0000395; P:mRNA 5'-splice site recognition; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006376; P:mRNA splice site selection; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF2_HUMAN             Reviewed;         221 AA.
AC   Q01130; B3KWD5;
DE   RecName: Full=Serine/arginine-rich splicing factor 2;
DE   AltName: Full=Protein PR264;
DE   AltName: Full=Splicing component, 35 kDa;
DE   AltName: Full=Splicing factor SC35;
DE            Short=SC-35;
DE   AltName: Full=Splicing factor, arginine/serine-rich 2;
GN   Name=SRSF2; Synonyms=SFRS2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; NAS:GOC.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF3_HUMAN             Reviewed;         164 AA.
AC   P84103; O08831; P23152; Q5R3K0;
DE   RecName: Full=Serine/arginine-rich splicing factor 3;
DE   AltName: Full=Pre-mRNA-splicing factor SRP20;
DE   AltName: Full=Splicing factor, arginine/serine-rich 3;
GN   Name=SRSF3; Synonyms=SFRS3, SRP20;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF4_HUMAN             Reviewed;         494 AA.
AC   Q08170; Q5VXP1; Q9BUA4; Q9UEB5;
DE   RecName: Full=Serine/arginine-rich splicing factor 4;
DE   AltName: Full=Pre-mRNA-splicing factor SRP75;
DE   AltName: Full=SRP001LB;
DE   AltName: Full=Splicing factor, arginine/serine-rich 4;
GN   Name=SRSF4; Synonyms=SFRS4, SRP75;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:ProtInc.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF6_HUMAN             Reviewed;         344 AA.
AC   Q13247; B7Z6J3; E1P5W6; Q13244; Q13245; Q96J06; Q9UJB8; Q9Y3N7;
DE   RecName: Full=Serine/arginine-rich splicing factor 6;
DE   AltName: Full=Pre-mRNA-splicing factor SRP55;
DE   AltName: Full=Splicing factor, arginine/serine-rich 6;
GN   Name=SRSF6; Synonyms=SFRS6, SRP55;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0036002; F:pre-mRNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006376; P:mRNA splice site selection; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0060548; P:negative regulation of cell death; IDA:MGI.
DR   GO; GO:0045617; P:negative regulation of keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IDA:MGI.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0010837; P:regulation of keratinocyte proliferation; IMP:UniProtKB.
DR   GO; GO:0061041; P:regulation of wound healing; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF7_HUMAN             Reviewed;         238 AA.
AC   Q16629; B4DLU6; G5E9M3; Q564D3;
DE   RecName: Full=Serine/arginine-rich splicing factor 7;
DE   AltName: Full=Splicing factor 9G8;
DE   AltName: Full=Splicing factor, arginine/serine-rich 7;
GN   Name=SRSF7; Synonyms=SFRS7;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF5_HUMAN             Reviewed;         272 AA.
AC   Q13243; O14797; Q16662; Q49AD6; Q6FGE0;
DE   RecName: Full=Serine/arginine-rich splicing factor 5;
DE   AltName: Full=Delayed-early protein HRS;
DE   AltName: Full=Pre-mRNA-splicing factor SRP40;
DE   AltName: Full=Splicing factor, arginine/serine-rich 5;
GN   Name=SRSF5; Synonyms=HRS, SFRS5, SRP40;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006376; P:mRNA splice site selection; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEA:Ensembl.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRSF8_HUMAN             Reviewed;         282 AA.
AC   Q9BRL6; B2R6B8; Q6PF01; Q96TA3;
DE   RecName: Full=Serine/arginine-rich splicing factor 8;
DE   AltName: Full=Pre-mRNA-splicing factor SRP46;
DE            Short=Splicing factor SRp46;
DE   AltName: Full=Splicing factor, arginine/serine-rich 2B;
GN   Name=SRSF8; Synonyms=SFRS2B, SRP46;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SRSF9_HUMAN             Reviewed;         221 AA.
AC   Q13242; Q52LD1;
DE   RecName: Full=Serine/arginine-rich splicing factor 9;
DE   AltName: Full=Pre-mRNA-splicing factor SRp30C;
DE   AltName: Full=Splicing factor, arginine/serine-rich 9;
GN   Name=SRSF9; Synonyms=SFRS9, SRP30C;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0006376; P:mRNA splice site selection; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   SRTD2_HUMAN             Reviewed;         314 AA.
AC   Q14140; Q53TS2;
DE   RecName: Full=SERTA domain-containing protein 2;
DE   AltName: Full=Transcriptional regulator interacting with the PHD-bromodomain 2;
DE            Short=TRIP-Br2;
GN   Name=SERTAD2; Synonyms=KIAA0127;
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRTD3_HUMAN             Reviewed;         196 AA.
AC   Q9UJW9; B3KQB3; Q96CQ2;
DE   RecName: Full=SERTA domain-containing protein 3;
DE   AltName: Full=Replication protein-binding trans-activator;
DE            Short=RPA-binding trans-activator;
GN   Name=SERTAD3; Synonyms=RBT1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRTD4_HUMAN             Reviewed;         356 AA.
AC   Q9NUC0; B2RD32;
DE   RecName: Full=SERTA domain-containing protein 4;
GN   Name=SERTAD4;
//
ID   SRTM1_HUMAN             Reviewed;         107 AA.
AC   A2A2V5; Q8N469;
DE   RecName: Full=Serine-rich and transmembrane domain-containing protein 1;
GN   Name=SERTM1; Synonyms=C13orf36;
//
ID   SRTD1_HUMAN             Reviewed;         236 AA.
AC   Q9UHV2; Q9BUE7;
DE   RecName: Full=SERTA domain-containing protein 1;
DE   AltName: Full=CDK4-binding protein p34SEI1;
DE            Short=SEI-1;
DE   AltName: Full=Transcriptional regulator interacting with the PHD-bromodomain 1;
DE            Short=TRIP-Br1;
GN   Name=SERTAD1; Synonyms=SEI1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SRXN1_HUMAN             Reviewed;         137 AA.
AC   Q9BYN0; B2R543; Q8NDM3; Q96AK6;
DE   RecName: Full=Sulfiredoxin-1;
DE            EC=1.8.98.2;
GN   Name=SRXN1; Synonyms=C20orf139, SRX;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016667; F:oxidoreductase activity, acting on a sulfur group of donors; IDA:UniProtKB.
DR   GO; GO:0032542; F:sulfiredoxin activity; IEA:UniProtKB-EC.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
//
ID   SRY_HUMAN               Reviewed;         204 AA.
AC   Q05066;
DE   RecName: Full=Sex-determining region Y protein;
DE   AltName: Full=Testis-determining factor;
GN   Name=SRY; Synonyms=TDF;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030238; P:male sex determination; NAS:UniProtKB.
DR   GO; GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   SSA27_HUMAN             Reviewed;         199 AA.
AC   O60232;
DE   RecName: Full=Sjoegren syndrome/scleroderma autoantigen 1;
DE   AltName: Full=Autoantigen p27;
GN   Name=SSSCA1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
//
ID   SSAS1_HUMAN             Reviewed;         100 AA.
AC   Q7Z2R9;
DE   RecName: Full=Putative uncharacterized protein SSBP3-AS1;
DE   AltName: Full=SSBP3 antisense RNA 1;
DE   AltName: Full=SSBP3 antisense gene protein 1;
DE   Flags: Precursor;
GN   Name=SSBP3-AS1; Synonyms=C1orf191; ORFNames=MSTP128;
//
ID   SSBP2_HUMAN             Reviewed;         361 AA.
AC   P81877; B2R5W1; B7Z1J2; B7Z2L9; B7Z665; D6RH18; E9PB74; E9PDA8;
AC   Q8N2Q2; Q9BWW6; Q9Y4T7;
DE   RecName: Full=Single-stranded DNA-binding protein 2;
DE   AltName: Full=Sequence-specific single-stranded-DNA-binding protein 2;
GN   Name=SSBP2; Synonyms=SSDP2;
DR   GO; GO:0003697; F:single-stranded DNA binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   SSBP3_HUMAN             Reviewed;         388 AA.
AC   Q9BWW4; A8K0A9; Q5T860; Q5T861; Q9BTM0; Q9BWW3;
DE   RecName: Full=Single-stranded DNA-binding protein 3;
DE   AltName: Full=Sequence-specific single-stranded-DNA-binding protein;
GN   Name=SSBP3; Synonyms=SSDP, SSDP1;
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0060323; P:head morphogenesis; IEA:Ensembl.
DR   GO; GO:0021547; P:midbrain-hindbrain boundary initiation; IEA:Ensembl.
DR   GO; GO:2000744; P:positive regulation of anterior head development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0021501; P:prechordal plate formation; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSBP4_HUMAN             Reviewed;         385 AA.
AC   Q9BWG4; Q9BWW5;
DE   RecName: Full=Single-stranded DNA-binding protein 4;
GN   Name=SSBP4;
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
//
ID   SSBP_HUMAN              Reviewed;         148 AA.
AC   Q04837;
DE   RecName: Full=Single-stranded DNA-binding protein, mitochondrial;
DE            Short=Mt-SSB;
DE            Short=MtSSB;
DE   AltName: Full=PWP1-interacting protein 17;
DE   Flags: Precursor;
GN   Name=SSBP1; Synonyms=SSBP;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IEA:Ensembl.
DR   GO; GO:0051096; P:positive regulation of helicase activity; IDA:UniProtKB.
//
ID   SSDH_HUMAN              Reviewed;         535 AA.
AC   P51649; B2RD26; G5E949; Q546H9; Q8N3W6;
DE   RecName: Full=Succinate-semialdehyde dehydrogenase, mitochondrial;
DE            EC=1.2.1.24;
DE   AltName: Full=Aldehyde dehydrogenase family 5 member A1;
DE   AltName: Full=NAD(+)-dependent succinic semialdehyde dehydrogenase;
DE   Flags: Precursor;
GN   Name=ALDH5A1; Synonyms=SSADH;
DR   GO; GO:0042803; F:protein homodimerization activity; IC:UniProtKB.
DR   GO; GO:0004777; F:succinate-semialdehyde dehydrogenase (NAD+) activity; IDA:UniProtKB.
DR   GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro.
DR   GO; GO:0006083; P:acetate metabolic process; ISS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IMP:UniProtKB.
DR   GO; GO:0006681; P:galactosylceramide metabolic process; ISS:UniProtKB.
DR   GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; IDA:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; ISS:UniProtKB.
DR   GO; GO:0006678; P:glucosylceramide metabolic process; IEA:Ensembl.
DR   GO; GO:0006536; P:glutamate metabolic process; ISS:UniProtKB.
DR   GO; GO:0006541; P:glutamine metabolic process; ISS:UniProtKB.
DR   GO; GO:0006749; P:glutathione metabolic process; ISS:UniProtKB.
DR   GO; GO:0006650; P:glycerophospholipid metabolic process; ISS:UniProtKB.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; ISS:UniProtKB.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0051289; P:protein homotetramerization; IDA:UniProtKB.
DR   GO; GO:0022904; P:respiratory electron transport chain; ISS:UniProtKB.
DR   GO; GO:0046459; P:short-chain fatty acid metabolic process; ISS:UniProtKB.
DR   GO; GO:0006105; P:succinate metabolic process; ISS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   SSF1_HUMAN              Reviewed;         473 AA.
AC   Q9NQ55; C9J3F9; Q9BW97; Q9H170;
DE   RecName: Full=Suppressor of SWI4 1 homolog;
DE            Short=Ssf-1;
DE   AltName: Full=Brix domain-containing protein 3;
DE   AltName: Full=Peter Pan homolog;
GN   Name=PPAN; Synonyms=BXDC3, SSF1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   SSFA2_HUMAN             Reviewed;        1259 AA.
AC   P28290; A8K6T0; Q68DA6; Q7Z7L2; Q8N1L3; Q8N263; Q8N7H2; Q8NEN5;
AC   Q96E36; Q96PW1;
DE   RecName: Full=Sperm-specific antigen 2;
DE   AltName: Full=Cleavage signal-1 protein;
DE            Short=CS-1;
DE   AltName: Full=Ki-ras-induced actin-interacting protein;
GN   Name=SSFA2; Synonyms=CS1, KIAA1927, KRAP;
//
ID   SSH1_HUMAN              Reviewed;        1049 AA.
AC   Q8WYL5; Q6P6C0; Q8N9A7; Q8WYL3; Q8WYL4; Q9P2P8;
DE   RecName: Full=Protein phosphatase Slingshot homolog 1;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=SSH-like protein 1;
DE            Short=SSH-1L;
DE            Short=hSSH-1L;
GN   Name=SSH1; Synonyms=KIAA1298, SSH1L;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0071318; P:cellular response to ATP; IDA:MGI.
DR   GO; GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.
DR   GO; GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.
DR   GO; GO:0032268; P:regulation of cellular protein metabolic process; IDA:MGI.
DR   GO; GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
//
ID   SSH2_HUMAN              Reviewed;        1423 AA.
AC   Q76I76; Q8TDB5; Q8WYL1; Q8WYL2; Q96F40; Q96H36; Q9C0D8;
DE   RecName: Full=Protein phosphatase Slingshot homolog 2;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=SSH-like protein 2;
DE            Short=SSH-2L;
DE            Short=hSSH-2L;
GN   Name=SSH2; Synonyms=KIAA1725, SSH2L;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0006470; P:protein dephosphorylation; IMP:UniProtKB.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.
DR   GO; GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.
DR   GO; GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
//
ID   SSH3_HUMAN              Reviewed;         659 AA.
AC   Q8TE77; Q6PK42; Q76I75; Q8N9L8; Q8WYL0; Q9NV45; Q9NWZ7;
DE   RecName: Full=Protein phosphatase Slingshot homolog 3;
DE            EC=3.1.3.16;
DE            EC=3.1.3.48;
DE   AltName: Full=SSH-like protein 3;
DE            Short=SSH-3L;
DE            Short=hSSH-3L;
GN   Name=SSH3; Synonyms=SSH3L;
DR   GO; GO:0003779; F:actin binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.
DR   GO; GO:0006470; P:protein dephosphorylation; IBA:RefGenome.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.
DR   GO; GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.
DR   GO; GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome.
//
ID   SSMM1_HUMAN             Reviewed;         244 AA.
AC   Q8WWF3;
DE   RecName: Full=Serine-rich single-pass membrane protein 1;
GN   Name=SSMEM1; Synonyms=C7orf45;
//
ID   SSNA1_HUMAN             Reviewed;         119 AA.
AC   O43805; Q5VSG0; Q6FG70; Q9BVW8;
DE   RecName: Full=Sjoegren syndrome nuclear autoantigen 1;
DE   AltName: Full=Nuclear autoantigen of 14 kDa;
GN   Name=SSNA1; Synonyms=NA14;
DR   GO; GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042073; P:intraciliary transport; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   SSPN_HUMAN              Reviewed;         243 AA.
AC   Q14714; B3KS67;
DE   RecName: Full=Sarcospan;
DE   AltName: Full=K-ras oncogene-associated protein;
DE   AltName: Full=Kirsten-ras-associated protein;
GN   Name=SSPN; Synonyms=KRAG;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   SSPO_HUMAN              Reviewed;        5147 AA.
AC   A2VEC9; Q76B61;
DE   RecName: Full=SCO-spondin;
DE   Flags: Precursor;
GN   Name=SSPO; Synonyms=KIAA2036;
DR   GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SSR1_HUMAN              Reviewed;         391 AA.
AC   P30872;
DE   RecName: Full=Somatostatin receptor type 1;
DE            Short=SS-1-R;
DE            Short=SS1-R;
DE            Short=SS1R;
DE   AltName: Full=SRIF-2;
GN   Name=SSTR1;
DR   GuidetoPHARMACOLOGY; 355; -.
DR   GO; GO:0004994; F:somatostatin receptor activity; IDA:MGI.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0007215; P:glutamate receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   SSR2_HUMAN              Reviewed;         369 AA.
AC   P30874; A8K3Y0; B2R9P7; Q4VBP0; Q96GE0; Q96TF2; Q9BWH1;
DE   RecName: Full=Somatostatin receptor type 2;
DE            Short=SS-2-R;
DE            Short=SS2-R;
DE            Short=SS2R;
DE   AltName: Full=SRIF-1;
GN   Name=SSTR2;
DR   GuidetoPHARMACOLOGY; 356; -.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004994; F:somatostatin receptor activity; TAS:ProtInc.
DR   GO; GO:0007193; P:adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0030432; P:peristalsis; IEA:Ensembl.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   SSR3_HUMAN              Reviewed;         418 AA.
AC   P32745; A8K550; Q53ZR7;
DE   RecName: Full=Somatostatin receptor type 3;
DE            Short=SS-3-R;
DE            Short=SS3-R;
DE            Short=SS3R;
DE   AltName: Full=SSR-28;
GN   Name=SSTR3;
DR   GuidetoPHARMACOLOGY; 357; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004994; F:somatostatin receptor activity; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0008628; P:hormone-mediated apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0038170; P:somatostatin signaling pathway; TAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   SSR5_HUMAN              Reviewed;         364 AA.
AC   P35346; P34988; Q541E0; Q9UJI5;
DE   RecName: Full=Somatostatin receptor type 5;
DE            Short=SS-5-R;
DE            Short=SS5-R;
DE            Short=SS5R;
GN   Name=SSTR5;
DR   GuidetoPHARMACOLOGY; 359; -.
DR   GO; GO:0004994; F:somatostatin receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0038170; P:somatostatin signaling pathway; TAS:GOC.
//
ID   SSR4_HUMAN              Reviewed;         388 AA.
AC   P31391; Q17RM1; Q17RM3; Q9UIY1;
DE   RecName: Full=Somatostatin receptor type 4;
DE            Short=SS-4-R;
DE            Short=SS4-R;
DE            Short=SS4R;
GN   Name=SSTR4;
DR   GuidetoPHARMACOLOGY; 358; -.
DR   GO; GO:0004994; F:somatostatin receptor activity; TAS:ProtInc.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0030815; P:negative regulation of cAMP metabolic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
//
ID   SSRA_HUMAN              Reviewed;         286 AA.
AC   P43307; A8K685; Q53GX2; Q53H19; Q5TAM3; Q6IB43; Q8NBH9; Q96IA2;
AC   Q9TNQ8; Q9UN49;
DE   RecName: Full=Translocon-associated protein subunit alpha;
DE            Short=TRAP-alpha;
DE   AltName: Full=Signal sequence receptor subunit alpha;
DE            Short=SSR-alpha;
DE   Flags: Precursor;
GN   Name=SSR1; Synonyms=TRAPA; ORFNames=PSEC0262;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SSRB_HUMAN              Reviewed;         183 AA.
AC   P43308; B2R9K9; D3DVA7; Q53HI0; Q5VY95; Q5VY96; Q6IB31; Q9BWE4;
DE   RecName: Full=Translocon-associated protein subunit beta;
DE            Short=TRAP-beta;
DE   AltName: Full=Signal sequence receptor subunit beta;
DE            Short=SSR-beta;
DE   Flags: Precursor;
GN   Name=SSR2; Synonyms=TRAPB; ORFNames=HSD25;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SSRG_HUMAN              Reviewed;         185 AA.
AC   Q9UNL2; B2R7D0; D3DNK5; Q549M4;
DE   RecName: Full=Translocon-associated protein subunit gamma;
DE            Short=TRAP-gamma;
DE   AltName: Full=Signal sequence receptor subunit gamma;
DE            Short=SSR-gamma;
GN   Name=SSR3; Synonyms=TRAPG;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SSRD_HUMAN              Reviewed;         173 AA.
AC   P51571; A8K378; Q53XY1;
DE   RecName: Full=Translocon-associated protein subunit delta;
DE            Short=TRAP-delta;
DE   AltName: Full=Signal sequence receptor subunit delta;
DE            Short=SSR-delta;
DE   Flags: Precursor;
GN   Name=SSR4; Synonyms=TRAPD;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
//
ID   SSRP1_HUMAN             Reviewed;         709 AA.
AC   Q08945; Q5BJG8;
DE   RecName: Full=FACT complex subunit SSRP1;
DE   AltName: Full=Chromatin-specific transcription elongation factor 80 kDa subunit;
DE   AltName: Full=Facilitates chromatin transcription complex 80 kDa subunit;
DE            Short=FACT 80 kDa subunit;
DE            Short=FACTp80;
DE   AltName: Full=Facilitates chromatin transcription complex subunit SSRP1;
DE   AltName: Full=Recombination signal sequence recognition protein 1;
DE   AltName: Full=Structure-specific recognition protein 1;
DE            Short=hSSRP1;
DE   AltName: Full=T160;
GN   Name=SSRP1; Synonyms=FACT80;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   SSU72_HUMAN             Reviewed;         194 AA.
AC   Q9NP77; Q9BZS6; Q9H933;
DE   RecName: Full=RNA polymerase II subunit A C-terminal domain phosphatase SSU72;
DE            Short=CTD phosphatase SSU72;
DE            EC=3.1.3.16;
GN   Name=SSU72; ORFNames=HSPC182, PNAS-120;
DR   GO; GO:0008420; F:CTD phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070940; P:dephosphorylation of RNA polymerase II C-terminal domain; IDA:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
//
ID   SSUH2_HUMAN             Reviewed;         353 AA.
AC   Q9Y2M2; A6NFA9; B3KS84; B7Z6E3; F5H2S5; Q7Z7K4;
DE   RecName: Full=Protein SSUH2 homolog;
DE   AltName: Full=Protein ssu-2 homolog;
GN   Name=SSUH2; Synonyms=C3orf32; ORFNames=FLS485;
//
ID   SSX1_HUMAN              Reviewed;         188 AA.
AC   Q16384; A3KN76; Q08AJ2; Q5JQ64;
DE   RecName: Full=Protein SSX1;
DE   AltName: Full=Cancer/testis antigen 5.1;
DE            Short=CT5.1;
DE   AltName: Full=Synovial sarcoma, X breakpoint 1;
GN   Name=SSX1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX10_HUMAN             Reviewed;         151 AA.
AC   A6NEJ1;
DE   RecName: Full=Putative protein SSX10;
GN   Name=SSX10;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX2_HUMAN              Reviewed;         188 AA.
AC   Q16385; Q16404; Q5JS26; Q96IP7; Q9BU88;
DE   RecName: Full=Protein SSX2;
DE   AltName: Full=Cancer/testis antigen 5.2;
DE            Short=CT5.2;
DE   AltName: Full=Synovial sarcoma, X breakpoint 2;
DE   AltName: Full=Tumor antigen HOM-MEL-40;
GN   Name=SSX2; Synonyms=SSX2A;
GN   and
GN   Name=SSX2B;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX3_HUMAN              Reviewed;         188 AA.
AC   Q99909; O60223; Q5JQZ3; Q9BRW7;
DE   RecName: Full=Protein SSX3;
DE   AltName: Full=Cancer/testis antigen 5.3;
DE            Short=CT5.3;
GN   Name=SSX3;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX4_HUMAN              Reviewed;         188 AA.
AC   O60224; A8MYD4; B2RPE3; Q3SYD4; Q5JQZ0; Q9UJU9;
DE   RecName: Full=Protein SSX4;
DE   AltName: Full=Cancer/testis antigen 5.4;
DE            Short=CT5.4;
GN   Name=SSX4; Synonyms=SSX4A;
GN   and
GN   Name=SSX4B;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX5_HUMAN              Reviewed;         188 AA.
AC   O60225; Q5JQ59; Q5JQ60; Q96AW3;
DE   RecName: Full=Protein SSX5;
GN   Name=SSX5;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX6_HUMAN              Reviewed;         188 AA.
AC   Q7RTT6;
DE   RecName: Full=Putative protein SSX6;
GN   Name=SSX6;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX7_HUMAN              Reviewed;         188 AA.
AC   Q7RTT5;
DE   RecName: Full=Protein SSX7;
GN   Name=SSX7;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSXT_HUMAN              Reviewed;         418 AA.
AC   Q15532; B0YJ95; Q16404; Q4VAX1; Q9BXC6;
DE   RecName: Full=Protein SSXT;
DE   AltName: Full=Protein SYT;
DE   AltName: Full=Synovial sarcoma translocated to X chromosome protein;
GN   Name=SS18; Synonyms=SSXT, SYT;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX9_HUMAN              Reviewed;         188 AA.
AC   Q7RTT3;
DE   RecName: Full=Protein SSX9;
GN   Name=SSX9;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SSX8_HUMAN              Reviewed;         187 AA.
AC   Q7RTT4; A6NJM6;
DE   RecName: Full=Protein SSX8;
GN   Name=SSX8;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ST134_HUMAN             Reviewed;         240 AA.
AC   Q8IZP2;
DE   RecName: Full=Putative protein FAM10A4;
DE   AltName: Full=Suppression of tumorigenicity 13 pseudogene 4;
GN   Name=ST13P4; Synonyms=FAM10A4;
//
ID   ST14_HUMAN              Reviewed;         855 AA.
AC   Q9Y5Y6; Q9BS01; Q9H3S0; Q9HB36; Q9HCA3;
DE   RecName: Full=Suppressor of tumorigenicity 14 protein;
DE            EC=3.4.21.109;
DE   AltName: Full=Matriptase;
DE   AltName: Full=Membrane-type serine protease 1;
DE            Short=MT-SP1;
DE   AltName: Full=Prostamin;
DE   AltName: Full=Serine protease 14;
DE   AltName: Full=Serine protease TADG-15;
DE   AltName: Full=Tumor-associated differentially-expressed gene 15 protein;
GN   Name=ST14; Synonyms=PRSS14, SNC19, TADG15;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   ST17A_HUMAN             Reviewed;         414 AA.
AC   Q9UEE5; A4D1V6; Q8IVC8;
DE   RecName: Full=Serine/threonine-protein kinase 17A;
DE            EC=2.7.11.1;
DE   AltName: Full=DAP kinase-related apoptosis-inducing protein kinase 1;
GN   Name=STK17A; Synonyms=DRAK1;
DR   GuidetoPHARMACOLOGY; 2214; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
//
ID   ST17B_HUMAN             Reviewed;         372 AA.
AC   O94768;
DE   RecName: Full=Serine/threonine-protein kinase 17B;
DE            EC=2.7.11.1;
DE   AltName: Full=DAP kinase-related apoptosis-inducing protein kinase 2;
GN   Name=STK17B; Synonyms=DRAK2;
DR   GuidetoPHARMACOLOGY; 2215; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:2000271; P:positive regulation of fibroblast apoptotic process; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   ST18_HUMAN              Reviewed;        1047 AA.
AC   O60284; Q17RY1;
DE   RecName: Full=Suppression of tumorigenicity 18 protein;
DE   AltName: Full=Zinc finger protein 387;
GN   Name=ST18; Synonyms=KIAA0535, ZNF387;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ST1A1_HUMAN             Reviewed;         295 AA.
AC   P50225; Q2NL71; Q86U58; Q92818; Q9BVU6; Q9UGG7;
DE   RecName: Full=Sulfotransferase 1A1;
DE            Short=ST1A1;
DE            EC=2.8.2.1;
DE   AltName: Full=Aryl sulfotransferase 1;
DE   AltName: Full=HAST1/HAST2;
DE   AltName: Full=Phenol sulfotransferase 1;
DE   AltName: Full=Phenol-sulfating phenol sulfotransferase 1;
DE            Short=P-PST 1;
DE   AltName: Full=ST1A3;
DE   AltName: Full=Thermostable phenol sulfotransferase;
DE            Short=Ts-PST;
GN   Name=SULT1A1; Synonyms=STP, STP1; ORFNames=OK/SW-cl.88;
DR   GO; GO:0004062; F:aryl sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0047894; F:flavonol 3-sulfotransferase activity; IDA:BHF-UCL.
DR   GO; GO:0050294; F:steroid sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0009308; P:amine metabolic process; TAS:ProtInc.
DR   GO; GO:0006584; P:catecholamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.
DR   GO; GO:0009812; P:flavonoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   ST1A2_HUMAN             Reviewed;         295 AA.
AC   P50226; A9QY25; P78393; Q14CJ7;
DE   RecName: Full=Sulfotransferase 1A2;
DE            Short=ST1A2;
DE            EC=2.8.2.1;
DE   AltName: Full=Aryl sulfotransferase 2;
DE   AltName: Full=Phenol sulfotransferase 2;
DE   AltName: Full=Phenol-sulfating phenol sulfotransferase 2;
DE            Short=P-PST 2;
GN   Name=SULT1A2; Synonyms=STP2;
DR   GO; GO:0004062; F:aryl sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0047894; F:flavonol 3-sulfotransferase activity; IDA:BHF-UCL.
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0009309; P:amine biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006584; P:catecholamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0018958; P:phenol-containing compound metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   ST1A3_HUMAN             Reviewed;         295 AA.
AC   P50224; B4DNV0; O95603; Q1ET66; Q6ZWJ5;
DE   RecName: Full=Sulfotransferase 1A3/1A4;
DE            Short=ST1A3/ST1A4;
DE            EC=2.8.2.1;
DE   AltName: Full=Aryl sulfotransferase 1A3/1A4;
DE   AltName: Full=Catecholamine-sulfating phenol sulfotransferase;
DE   AltName: Full=HAST3;
DE   AltName: Full=M-PST;
DE   AltName: Full=Monoamine-sulfating phenol sulfotransferase;
DE   AltName: Full=Placental estrogen sulfotransferase;
DE   AltName: Full=Sulfotransferase, monoamine-preferring;
DE   AltName: Full=Thermolabile phenol sulfotransferase;
DE            Short=TL-PST;
GN   Name=SULT1A3; Synonyms=STM;
GN   and
GN   Name=SULT1A4;
DR   GO; GO:0004062; F:aryl sulfotransferase activity; TAS:Reactome.
DR   GO; GO:0008146; F:sulfotransferase activity; IDA:BHF-UCL.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0006584; P:catecholamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0009812; P:flavonoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:BHF-UCL.
//
ID   ST1B1_HUMAN             Reviewed;         296 AA.
AC   O43704; O15497; Q96FI1; Q9UK34;
DE   RecName: Full=Sulfotransferase family cytosolic 1B member 1;
DE            Short=ST1B1;
DE            Short=Sulfotransferase 1B1;
DE            EC=2.8.2.-;
DE   AltName: Full=Sulfotransferase 1B2;
DE            Short=ST1B2;
DE   AltName: Full=Thyroid hormone sulfotransferase;
GN   Name=SULT1B1; Synonyms=ST1B2, SULT1B2;
DR   GO; GO:0004062; F:aryl sulfotransferase activity; IEA:Ensembl.
DR   GO; GO:0008146; F:sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0006576; P:cellular biogenic amine metabolic process; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0009812; P:flavonoid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0018958; P:phenol-containing compound metabolic process; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0042403; P:thyroid hormone metabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:BHF-UCL.
//
ID   ST1C2_HUMAN             Reviewed;         296 AA.
AC   O00338; B2R813; Q53SG4;
DE   RecName: Full=Sulfotransferase 1C2;
DE            Short=ST1C2;
DE            EC=2.8.2.-;
DE   AltName: Full=Sulfotransferase 1C1;
DE            Short=SULT1C#1;
DE   AltName: Full=humSULTC2;
GN   Name=SULT1C2; Synonyms=SULT1C1;
DR   GO; GO:0008146; F:sulfotransferase activity; IDA:BHF-UCL.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0009308; P:amine metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ST1C3_HUMAN             Reviewed;         304 AA.
AC   Q6IMI6; Q6IMI5;
DE   RecName: Full=Sulfotransferase 1C3;
DE            Short=ST1C3;
DE            EC=2.8.2.2;
GN   Name=SULT1C3;
DR   GO; GO:0004027; F:alcohol sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0004062; F:aryl sulfotransferase activity; IEA:Ensembl.
DR   GO; GO:0006790; P:sulfur compound metabolic process; IEA:Ensembl.
//
ID   ST1C4_HUMAN             Reviewed;         302 AA.
AC   O75897; Q069I8; Q53S63;
DE   RecName: Full=Sulfotransferase 1C4;
DE            Short=ST1C4;
DE            EC=2.8.2.-;
DE   AltName: Full=Sulfotransferase 1C2;
DE            Short=SULT1C#2;
GN   Name=SULT1C4; Synonyms=SULT1C2;
DR   GO; GO:0008146; F:sulfotransferase activity; NAS:UniProtKB.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ST1E1_HUMAN             Reviewed;         294 AA.
AC   P49888; Q8N6X5;
DE   RecName: Full=Estrogen sulfotransferase;
DE            EC=2.8.2.4;
DE   AltName: Full=EST-1;
DE   AltName: Full=Sulfotransferase 1E1;
DE            Short=ST1E1;
DE   AltName: Full=Sulfotransferase, estrogen-preferring;
GN   Name=SULT1E1; Synonyms=STE;
DR   GO; GO:0004304; F:estrone sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0047894; F:flavonol 3-sulfotransferase activity; IDA:BHF-UCL.
DR   GO; GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
DR   GO; GO:0050294; F:steroid sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ST20_HUMAN              Reviewed;          79 AA.
AC   Q9HBF5;
DE   RecName: Full=Suppressor of tumorigenicity 20 protein;
DE   AltName: Full=Human cervical cancer suppressor gene 1 protein;
DE            Short=HCCS-1;
GN   Name=ST20; Synonyms=HCCS1;
DR   GO; GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.
DR   GO; GO:0042803; F:protein homodimerization activity; IBA:RefGenome.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IBA:RefGenome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IBA:RefGenome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IBA:RefGenome.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IBA:RefGenome.
//
ID   ST2A1_HUMAN             Reviewed;         285 AA.
AC   Q06520;
DE   RecName: Full=Bile salt sulfotransferase;
DE            EC=2.8.2.14;
DE   AltName: Full=Dehydroepiandrosterone sulfotransferase;
DE            Short=DHEA-ST;
DE   AltName: Full=Hydroxysteroid Sulfotransferase;
DE            Short=HST;
DE   AltName: Full=ST2;
DE   AltName: Full=ST2A3;
DE   AltName: Full=Sulfotransferase 2A1;
DE            Short=ST2A1;
GN   Name=SULT2A1; Synonyms=HST, STD;
DR   GO; GO:0047704; F:bile-salt sulfotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008146; F:sulfotransferase activity; IDA:BHF-UCL.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0007586; P:digestion; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
DR   GO; GO:0051923; P:sulfation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ST2B1_HUMAN             Reviewed;         365 AA.
AC   O00204; O00205; O75814;
DE   RecName: Full=Sulfotransferase family cytosolic 2B member 1;
DE            Short=ST2B1;
DE            Short=Sulfotransferase 2B1;
DE            EC=2.8.2.2;
DE   AltName: Full=Alcohol sulfotransferase;
DE   AltName: Full=Hydroxysteroid sulfotransferase 2;
GN   Name=SULT2B1; Synonyms=HSST2;
DR   GO; GO:0004027; F:alcohol sulfotransferase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050294; F:steroid sulfotransferase activity; IDA:UniProtKB.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IDA:UniProtKB.
DR   GO; GO:0000103; P:sulfate assimilation; IEA:Ensembl.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ST32A_HUMAN             Reviewed;         396 AA.
AC   Q8WU08; B3KSY0;
DE   RecName: Full=Serine/threonine-protein kinase 32A;
DE            EC=2.7.11.1;
DE   AltName: Full=Yet another novel kinase 1;
GN   Name=STK32A; Synonyms=YANK1;
DR   GuidetoPHARMACOLOGY; 1537; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ST32B_HUMAN             Reviewed;         414 AA.
AC   Q9NY57; Q6UXH3; Q8IY14;
DE   RecName: Full=Serine/threonine-protein kinase 32B;
DE            EC=2.7.11.1;
DE   AltName: Full=Yet another novel kinase 2;
GN   Name=STK32B; Synonyms=YANK2; ORFNames=UNQ3003/PRO9744;
DR   GuidetoPHARMACOLOGY; 1538; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ST32C_HUMAN             Reviewed;         486 AA.
AC   Q86UX6; Q5T0Q5; Q86UE1;
DE   RecName: Full=Serine/threonine-protein kinase 32C;
DE            EC=2.7.11.1;
DE   AltName: Full=PKE;
DE   AltName: Full=Yet another novel kinase 3;
GN   Name=STK32C; Synonyms=YANK3;
DR   GuidetoPHARMACOLOGY; 1539; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   ST38L_HUMAN             Reviewed;         464 AA.
AC   Q9Y2H1; A8K4U0; Q8TBX7;
DE   RecName: Full=Serine/threonine-protein kinase 38-like;
DE            EC=2.7.11.1;
DE   AltName: Full=NDR2 protein kinase;
DE   AltName: Full=Nuclear Dbf2-related kinase 2;
GN   Name=STK38L; Synonyms=KIAA0965, NDR2;
DR   GuidetoPHARMACOLOGY; 1518; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051128; P:regulation of cellular component organization; ISS:UniProtKB.
//
ID   ST3L3_HUMAN             Reviewed;         134 AA.
AC   P0CL85; A6NMT8; A8K0A1; Q32NE4; Q6NXR2; Q7L5M5; Q7Z5K6;
DE   RecName: Full=STAG3-like protein 3;
DE   AltName: Full=Stromal antigen 3-like protein 3;
GN   Name=STAG3L3;
//
ID   ST4A1_HUMAN             Reviewed;         284 AA.
AC   Q9BR01; B2R7N3; O43728;
DE   RecName: Full=Sulfotransferase 4A1;
DE            Short=ST4A1;
DE            EC=2.8.2.-;
DE   AltName: Full=Brain sulfotransferase-like protein;
DE            Short=hBR-STL;
DE            Short=hBR-STL-1;
DE   AltName: Full=Nervous system sulfotransferase;
DE            Short=NST;
GN   Name=SULT4A1; Synonyms=SULTX3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008146; F:sulfotransferase activity; NAS:UniProtKB.
DR   GO; GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   ST3L4_HUMAN             Reviewed;         150 AA.
AC   Q8TBR4; Q9H8W0;
DE   RecName: Full=Putative STAG3-like protein 4;
DE   AltName: Full=Stromal antigen 3-like protein 4;
GN   Name=STAG3L4;
//
ID   ST3L2_HUMAN             Reviewed;         134 AA.
AC   P0CL84; A6NMT8; A8K0A1; Q32NE4; Q6NXR2; Q7L5M5; Q7Z5K6;
DE   RecName: Full=Putative STAG3-like protein 2;
DE   AltName: Full=Stromal antigen 3-like protein 2;
GN   Name=STAG3L2;
//
ID   ST3L1_HUMAN             Reviewed;         205 AA.
AC   P0CL83; A6NMT8; A8K0A1; Q32NE4; Q6NXR2; Q7L5M5; Q7Z5K6;
DE   RecName: Full=Putative STAG3-like protein 1;
DE   AltName: Full=Stromal antigen 3-like protein 1;
GN   Name=STAG3L1;
//
ID   ST5_HUMAN               Reviewed;        1137 AA.
AC   P78524; B2R6X7; B3KXQ6; P78523; Q16492; Q7KYY2; Q7KZ12; Q8NE12;
AC   Q9BQQ6;
DE   RecName: Full=Suppression of tumorigenicity 5 protein;
DE   AltName: Full=DENN domain-containing protein 2B;
DE   AltName: Full=HeLa tumor suppression 1;
GN   Name=ST5; Synonyms=DENND2B, HTS1;
DR   GO; GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:MGI.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:GOC.
//
ID   ST65G_HUMAN             Reviewed;         414 AA.
AC   O94864; B4E3W3; Q6IB21; Q9H2T6;
DE   RecName: Full=STAGA complex 65 subunit gamma;
DE   AltName: Full=Adenocarcinoma antigen ART1;
DE   AltName: Full=SPTF-associated factor 65 gamma;
DE            Short=STAF65gamma;
DE   AltName: Full=Suppressor of Ty 7-like;
GN   Name=SUPT7L; Synonyms=KIAA0764;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:HGNC.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ST6B1_HUMAN             Reviewed;         303 AA.
AC   Q6IMI4; B2RTS7;
DE   RecName: Full=Sulfotransferase 6B1;
DE            Short=ST6B1;
DE   AltName: Full=Thyroxine sulfotransferase;
DE            EC=2.8.2.n2;
GN   Name=SULT6B1;
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:UniProtKB-EC.
//
ID   ST7L_HUMAN              Reviewed;         575 AA.
AC   Q8TDW4; A8K4S7; Q49AH6; Q5TEI4; Q5U5K6; Q6N067; Q7Z2Z0; Q7Z3C2;
AC   Q8N7P8; Q8TDW1; Q8TDW2; Q8TDW3; Q9NXF3;
DE   RecName: Full=Suppressor of tumorigenicity 7 protein-like;
DE   AltName: Full=ST7-related protein;
GN   Name=ST7L; Synonyms=ST7R;
DR   GO; GO:0030308; P:negative regulation of cell growth; ISS:BHF-UCL.
//
ID   ST7_HUMAN               Reviewed;         585 AA.
AC   Q9NRC1; A4D0V2; Q5CZ72; Q7LE31; Q7LE32; Q8NA32; Q8NEJ8; Q8TDI9;
AC   Q9BWX3; Q9BWX4; Q9NRC2; Q9NXZ7;
DE   RecName: Full=Suppressor of tumorigenicity 7 protein;
DE   AltName: Full=Protein FAM4A1;
DE   AltName: Full=Protein HELG;
GN   Name=ST7; Synonyms=FAM4A1, HELG, RAY1;
//
ID   STA13_HUMAN             Reviewed;        1113 AA.
AC   Q9Y3M8; A2A309; A2A310; Q5HYH1; Q5TAE3; Q6UN61; Q86TP6; Q86WQ3;
AC   Q86XT1;
DE   RecName: Full=StAR-related lipid transfer protein 13;
DE   AltName: Full=46H23.2;
DE   AltName: Full=Deleted in liver cancer 2 protein;
DE            Short=DLC-2;
DE   AltName: Full=Rho GTPase-activating protein;
DE   AltName: Full=START domain-containing protein 13;
DE            Short=StARD13;
GN   Name=STARD13; Synonyms=DLC2, GT650;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   STA5A_HUMAN             Reviewed;         794 AA.
AC   P42229; Q1KLZ6;
DE   RecName: Full=Signal transducer and activator of transcription 5A;
GN   Name=STAT5A; Synonyms=STAT5;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0000255; P:allantoin metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006101; P:citrate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006600; P:creatine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046449; P:creatinine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046543; P:development of secondary female sexual characteristics; IEA:Ensembl.
DR   GO; GO:0046544; P:development of secondary male sexual characteristics; IEA:Ensembl.
DR   GO; GO:0060742; P:epithelial cell differentiation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006549; P:isoleucine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0007595; P:lactation; IEA:UniProtKB-KW.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0001553; P:luteinization; IEA:Ensembl.
DR   GO; GO:0061180; P:mammary gland epithelium development; IEA:Ensembl.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0033026; P:negative regulation of mast cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060376; P:positive regulation of mast cell differentiation; IEA:Ensembl.
DR   GO; GO:0070668; P:positive regulation of mast cell proliferation; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0038161; P:prolactin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0030856; P:regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:BHF-UCL.
DR   GO; GO:0019218; P:regulation of steroid metabolic process; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006105; P:succinate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0019530; P:taurine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006573; P:valine metabolic process; ISS:BHF-UCL.
//
ID   STA5B_HUMAN             Reviewed;         787 AA.
AC   P51692; Q8WWS8;
DE   RecName: Full=Signal transducer and activator of transcription 5B;
GN   Name=STAT5B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0035259; F:glucocorticoid receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; ISS:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0006103; P:2-oxoglutarate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IEA:Ensembl.
DR   GO; GO:0000255; P:allantoin metabolic process; ISS:BHF-UCL.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IDA:BHF-UCL.
DR   GO; GO:0006101; P:citrate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006600; P:creatine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046449; P:creatinine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0046543; P:development of secondary female sexual characteristics; IEA:Ensembl.
DR   GO; GO:0046544; P:development of secondary male sexual characteristics; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0006549; P:isoleucine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0019915; P:lipid storage; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0001553; P:luteinization; IEA:Ensembl.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045647; P:negative regulation of erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045579; P:positive regulation of B cell differentiation; IEA:Ensembl.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IEA:Ensembl.
DR   GO; GO:0045588; P:positive regulation of gamma-delta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0045954; P:positive regulation of natural killer cell mediated cytotoxicity; IEA:Ensembl.
DR   GO; GO:0032819; P:positive regulation of natural killer cell proliferation; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0042448; P:progesterone metabolic process; IEA:Ensembl.
DR   GO; GO:0038161; P:prolactin signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0030856; P:regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; ISS:BHF-UCL.
DR   GO; GO:0019218; P:regulation of steroid metabolic process; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0070672; P:response to interleukin-15; IEA:Ensembl.
DR   GO; GO:0070669; P:response to interleukin-2; IEA:Ensembl.
DR   GO; GO:0070670; P:response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0006105; P:succinate metabolic process; ISS:BHF-UCL.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0019530; P:taurine metabolic process; ISS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006573; P:valine metabolic process; ISS:BHF-UCL.
//
ID   STAB1_HUMAN             Reviewed;        2570 AA.
AC   Q9NY15; A7E297; Q8IUH0; Q8IUH1; Q93072;
DE   RecName: Full=Stabilin-1;
DE   AltName: Full=Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1;
DE            Short=FEEL-1;
DE   AltName: Full=MS-1 antigen;
DE   Flags: Precursor;
GN   Name=STAB1; Synonyms=FEEL1, KIAA0246;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; NAS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; NAS:GOC.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:UniProtKB.
//
ID   STAB2_HUMAN             Reviewed;        2551 AA.
AC   Q8WWQ8; Q6ZMK2; Q7Z5N9; Q86UR4; Q8IUG9; Q8TES1; Q9H7H7; Q9NRY3;
DE   RecName: Full=Stabilin-2;
DE   AltName: Full=FAS1 EGF-like and X-link domain-containing adhesion molecule 2;
DE   AltName: Full=Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2;
DE            Short=FEEL-2;
DE   AltName: Full=Hyaluronan receptor for endocytosis;
DE   Contains:
DE     RecName: Full=190 kDa form stabilin-2;
DE     AltName: Full=190 kDa hyaluronan receptor for endocytosis;
DE   Flags: Precursor;
GN   Name=STAB2; Synonyms=FEEL2, FELL, FEX2, HARE;
DR   GO; GO:0005540; F:hyaluronic acid binding; ISS:UniProtKB.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:UniProtKB.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; NAS:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0030214; P:hyaluronan catabolic process; TAS:Reactome.
DR   GO; GO:0030212; P:hyaluronan metabolic process; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; NAS:GOC.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; TAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   STABP_HUMAN             Reviewed;         424 AA.
AC   O95630; D6W5H7; Q3MJE7;
DE   RecName: Full=STAM-binding protein;
DE            EC=3.4.19.-;
DE   AltName: Full=Associated molecule with the SH3 domain of STAM;
DE   AltName: Full=Endosome-associated ubiquitin isopeptidase;
GN   Name=STAMBP; Synonyms=AMSH;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:MGI.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:MGI.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0016579; P:protein deubiquitination; IMP:MGI.
//
ID   STAC2_HUMAN             Reviewed;         411 AA.
AC   Q6ZMT1; Q32MA3;
DE   RecName: Full=SH3 and cysteine-rich domain-containing protein 2;
DE   AltName: Full=24b2/STAC2;
DE   AltName: Full=Src homology 3 and cysteine-rich domain-containing protein 2;
GN   Name=STAC2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   STAC3_HUMAN             Reviewed;         364 AA.
AC   Q96MF2; Q96HU5;
DE   RecName: Full=SH3 and cysteine-rich domain-containing protein 3;
GN   Name=STAC3;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
//
ID   STAC_HUMAN              Reviewed;         402 AA.
AC   Q99469; B2R8S8;
DE   RecName: Full=SH3 and cysteine-rich domain-containing protein;
DE   AltName: Full=Src homology 3 and cysteine-rich domain-containing protein;
GN   Name=STAC;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   STAG1_HUMAN             Reviewed;        1258 AA.
AC   Q8WVM7; O00539; Q6P275;
DE   RecName: Full=Cohesin subunit SA-1;
DE   AltName: Full=SCC3 homolog 1;
DE   AltName: Full=Stromal antigen 1;
GN   Name=STAG1; Synonyms=SA1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
//
ID   STAG2_HUMAN             Reviewed;        1231 AA.
AC   Q8N3U4; B1AMT5; D3DTF5; O00540; Q5JTI6; Q68DE9; Q9H1N8;
DE   RecName: Full=Cohesin subunit SA-2;
DE   AltName: Full=SCC3 homolog 2;
DE   AltName: Full=Stromal antigen 2;
GN   Name=STAG2; Synonyms=SA2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.
DR   GO; GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   STAG3_HUMAN             Reviewed;        1225 AA.
AC   Q9UJ98; A6H8Z1; B4DZ10; D6W5U8; H7BYK9; Q8NDP3;
DE   RecName: Full=Cohesin subunit SA-3;
DE   AltName: Full=SCC3 homolog 3;
DE   AltName: Full=Stromal antigen 3;
DE   AltName: Full=Stromalin-3;
GN   Name=STAG3;
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007130; P:synaptonemal complex assembly; TAS:ProtInc.
//
ID   STALP_HUMAN             Reviewed;         436 AA.
AC   Q96FJ0; B3KPA7; Q5T9N4; Q5T9N9; Q7Z420; Q9P2H4;
DE   RecName: Full=AMSH-like protease;
DE            Short=AMSH-LP;
DE            EC=3.4.19.-;
DE   AltName: Full=STAM-binding protein-like 1;
GN   Name=STAMBPL1; Synonyms=AMSHLP, KIAA1373;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   STAM1_HUMAN             Reviewed;         540 AA.
AC   Q92783; B0YJ99; D3DRU5; Q8N6D9;
DE   RecName: Full=Signal transducing adapter molecule 1;
DE            Short=STAM-1;
GN   Name=STAM; Synonyms=STAM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   STAM2_HUMAN             Reviewed;         525 AA.
AC   O75886; A8K8A0; D3DPA1; Q7LDQ0; Q9UF58;
DE   RecName: Full=Signal transducing adapter molecule 2;
DE            Short=STAM-2;
DE   AltName: Full=Hrs-binding protein;
GN   Name=STAM2; Synonyms=HBP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
//
ID   STAP1_HUMAN             Reviewed;         295 AA.
AC   Q9ULZ2; B2R980;
DE   RecName: Full=Signal-transducing adaptor protein 1;
DE            Short=STAP-1;
DE   AltName: Full=BCR downstream-signaling protein 1;
DE   AltName: Full=Docking protein BRDG1;
DE   AltName: Full=Stem cell adaptor protein 1;
GN   Name=STAP1; Synonyms=BRDG1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0009967; P:positive regulation of signal transduction; IEA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl.
//
ID   STAP2_HUMAN             Reviewed;         403 AA.
AC   Q9UGK3; A6NKK3; Q9NXI2;
DE   RecName: Full=Signal-transducing adaptor protein 2;
DE            Short=STAP-2;
DE   AltName: Full=Breast tumor kinase substrate;
DE            Short=BRK substrate;
GN   Name=STAP2; Synonyms=BKS;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   STAR3_HUMAN             Reviewed;         445 AA.
AC   Q14849; A8MXA4; B4DUY1; F5H0G2; Q53Y53; Q96HM9;
DE   RecName: Full=StAR-related lipid transfer protein 3;
DE   AltName: Full=Metastatic lymph node gene 64 protein;
DE            Short=MLN 64;
DE   AltName: Full=Protein CAB1;
DE   AltName: Full=START domain-containing protein 3;
DE            Short=StARD3;
GN   Name=STARD3; Synonyms=CAB1, MLN64;
DR   GO; GO:0015485; F:cholesterol binding; IDA:MGI.
DR   GO; GO:0017127; F:cholesterol transporter activity; IEA:InterPro.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006839; P:mitochondrial transport; TAS:ProtInc.
DR   GO; GO:0006701; P:progesterone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
//
ID   STAR4_HUMAN             Reviewed;         205 AA.
AC   Q96DR4;
DE   RecName: Full=StAR-related lipid transfer protein 4;
DE   AltName: Full=START domain-containing protein 4;
DE            Short=StARD4;
GN   Name=STARD4;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   STAR5_HUMAN             Reviewed;         213 AA.
AC   Q9NSY2; P59094;
DE   RecName: Full=StAR-related lipid transfer protein 5;
DE   AltName: Full=START domain-containing protein 5;
DE            Short=StARD5;
GN   Name=STARD5;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
//
ID   STAR6_HUMAN             Reviewed;         220 AA.
AC   P59095;
DE   RecName: Full=StAR-related lipid transfer protein 6;
DE   AltName: Full=START domain-containing protein 6;
DE            Short=StARD6;
GN   Name=STARD6;
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   STAR7_HUMAN             Reviewed;         370 AA.
AC   Q9NQZ5; D3DXG9; Q53T44; Q6GU43; Q969M6;
DE   RecName: Full=StAR-related lipid transfer protein 7, mitochondrial;
DE   AltName: Full=Gestational trophoblastic tumor protein 1;
DE   AltName: Full=START domain-containing protein 7;
DE            Short=StARD7;
DE   Flags: Precursor;
GN   Name=STARD7; Synonyms=GTT1;
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
//
ID   STAR8_HUMAN             Reviewed;        1023 AA.
AC   Q92502; A8K6T2; D3DVT9; Q5JST0; Q68DG7;
DE   RecName: Full=StAR-related lipid transfer protein 8;
DE   AltName: Full=Deleted in liver cancer 3 protein;
DE            Short=DLC-3;
DE   AltName: Full=START domain-containing protein 8;
DE            Short=StARD8;
DE   AltName: Full=START-GAP3;
GN   Name=STARD8; Synonyms=DLC3, KIAA0189;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   STAR9_HUMAN             Reviewed;        4700 AA.
AC   Q9P2P6; Q68DG2; Q6AI01; Q6ZWK0; Q9UF70;
DE   RecName: Full=StAR-related lipid transfer protein 9;
DE   AltName: Full=START domain-containing protein 9;
DE            Short=StARD9;
GN   Name=STARD9; Synonyms=KIAA1300;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0003777; F:microtubule motor activity; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   GO; GO:0051225; P:spindle assembly; IMP:UniProtKB.
//
ID   STAR_HUMAN              Reviewed;         285 AA.
AC   P49675; Q16396;
DE   RecName: Full=Steroidogenic acute regulatory protein, mitochondrial;
DE            Short=StAR;
DE   AltName: Full=START domain-containing protein 1;
DE            Short=StARD1;
DE   Flags: Precursor;
GN   Name=STAR; Synonyms=STARD1;
DR   GO; GO:0015485; F:cholesterol binding; IEA:Ensembl.
DR   GO; GO:0017127; F:cholesterol transporter activity; IEA:InterPro.
DR   GO; GO:0006699; P:bile acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0018879; P:biphenyl metabolic process; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006700; P:C21-steroid hormone biosynthetic process; TAS:Reactome.
DR   GO; GO:0071312; P:cellular response to alkaloid; IEA:Ensembl.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0071276; P:cellular response to cadmium ion; IEA:Ensembl.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; IEA:Ensembl.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071372; P:cellular response to follicle-stimulating hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071378; P:cellular response to growth hormone stimulus; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IEA:Ensembl.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071373; P:cellular response to luteinizing hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042747; P:circadian sleep/wake cycle, REM sleep; IEA:Ensembl.
DR   GO; GO:0018894; P:dibenzo-p-dioxin metabolic process; IEA:Ensembl.
DR   GO; GO:0016101; P:diterpenoid metabolic process; IEA:Ensembl.
DR   GO; GO:0006703; P:estrogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0050756; P:fractalkine metabolic process; IEA:Ensembl.
DR   GO; GO:0008211; P:glucocorticoid metabolic process; IEA:Ensembl.
DR   GO; GO:0017143; P:insecticide metabolic process; IEA:Ensembl.
DR   GO; GO:0032367; P:intracellular cholesterol transport; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0018958; P:phenol-containing compound metabolic process; IEA:Ensembl.
DR   GO; GO:0018963; P:phthalate metabolic process; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0006701; P:progesterone biosynthetic process; IEA:Ensembl.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0060992; P:response to fungicide; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0010288; P:response to lead ion; IEA:Ensembl.
DR   GO; GO:0044321; P:response to leptin; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0061370; P:testosterone biosynthetic process; IEA:Ensembl.
//
ID   STAT1_HUMAN             Reviewed;         750 AA.
AC   P42224; A8K989; B2RCA0; D2KFR8; D3DPI7; Q53S88; Q53XW4; Q68D00;
AC   Q9UDL5;
DE   RecName: Full=Signal transducer and activator of transcription 1-alpha/beta;
DE   AltName: Full=Transcription factor ISGF-3 components p91/p84;
GN   Name=STAT1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0000983; F:RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0008015; P:blood circulation; ISS:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IMP:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007259; P:JAK-STAT cascade; IDA:UniProtKB.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0072162; P:metanephric mesenchymal cell differentiation; ISS:UniProtKB.
DR   GO; GO:0072136; P:metanephric mesenchymal cell proliferation involved in metanephros development; ISS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0034240; P:negative regulation of macrophage fusion; IEA:Ensembl.
DR   GO; GO:0003340; P:negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; ISS:UniProtKB.
DR   GO; GO:0072308; P:negative regulation of metanephric nephron tubule epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0061326; P:renal tubule development; IMP:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; ISS:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; ISS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0060337; P:type I interferon signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   STAT2_HUMAN             Reviewed;         851 AA.
AC   P52630; B4DLC7; G3V2M6; Q16430; Q16431; Q9UDL4;
DE   RecName: Full=Signal transducer and activator of transcription 2;
DE   AltName: Full=p113;
GN   Name=STAT2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   STAT3_HUMAN             Reviewed;         770 AA.
AC   P40763; A8K7B8; O14916; Q9BW54;
DE   RecName: Full=Signal transducer and activator of transcription 3;
DE   AltName: Full=Acute-phase response factor;
GN   Name=STAT3; Synonyms=APRF;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; ISS:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; ISS:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IEA:Ensembl.
DR   GO; GO:0048708; P:astrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IDA:BHF-UCL.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; NAS:UniProtKB.
DR   GO; GO:0042755; P:eating behavior; ISS:UniProtKB.
DR   GO; GO:0001754; P:eye photoreceptor cell differentiation; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:UniProtKB.
DR   GO; GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; ISS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:2001223; P:negative regulation of neuron migration; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016310; P:phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006606; P:protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0060019; P:radial glial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0019953; P:sexual reproduction; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0001659; P:temperature homeostasis; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   STAT4_HUMAN             Reviewed;         748 AA.
AC   Q14765; Q96NZ6;
DE   RecName: Full=Signal transducer and activator of transcription 4;
GN   Name=STAT4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   STAT6_HUMAN             Reviewed;         847 AA.
AC   P42226; A8K316; B7ZA27; F5GXI9; Q5FBW5; Q71UP4;
DE   RecName: Full=Signal transducer and activator of transcription 6;
DE   AltName: Full=IL-4 Stat;
GN   Name=STAT6;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:1902170; P:cellular response to reactive nitrogen species; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035771; P:interleukin-4-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060443; P:mammary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0002829; P:negative regulation of type 2 immune response; IEA:Ensembl.
DR   GO; GO:0048295; P:positive regulation of isotype switching to IgE isotypes; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002296; P:T-helper 1 cell lineage commitment; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   STAT_HUMAN              Reviewed;          62 AA.
AC   P02808; A6NKE9; B2R4F8;
DE   RecName: Full=Statherin;
DE   Flags: Precursor;
GN   Name=STATH;
DR   GO; GO:0030197; F:extracellular matrix constituent, lubricant activity; NAS:UniProtKB.
DR   GO; GO:0046848; F:hydroxyapatite binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030345; F:structural constituent of tooth enamel; NAS:UniProtKB.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0030502; P:negative regulation of bone mineralization; NAS:UniProtKB.
DR   GO; GO:0001503; P:ossification; TAS:ProtInc.
DR   GO; GO:0046541; P:saliva secretion; NAS:UniProtKB.
//
ID   STAU1_HUMAN             Reviewed;         577 AA.
AC   O95793; A8K9Z4; E1P5Y1; E1P608; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5;
AC   Q9Y3Q2;
DE   RecName: Full=Double-stranded RNA-binding protein Staufen homolog 1;
GN   Name=STAU1; Synonyms=STAU;
DR   GO; GO:0003725; F:double-stranded RNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008298; P:intracellular mRNA localization; IEA:Ensembl.
//
ID   STAU2_HUMAN             Reviewed;         570 AA.
AC   Q9NUL3; B7Z1I6; B7Z292; B7Z8B4; E7ER74; E9PEI3; E9PF26; E9PF50;
AC   Q6AHY7; Q96HM0; Q96HM1; Q9NVI5; Q9UGG6;
DE   RecName: Full=Double-stranded RNA-binding protein Staufen homolog 2;
GN   Name=STAU2;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   STB5L_HUMAN             Reviewed;        1186 AA.
AC   Q9Y2K9; Q4G1B4; Q6PIC3;
DE   RecName: Full=Syntaxin-binding protein 5-like;
DE   AltName: Full=Lethal(2) giant larvae protein homolog 4;
DE   AltName: Full=Tomosyn-2;
GN   Name=STXBP5L; Synonyms=KIAA1006, LLGL4;
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
//
ID   STBD1_HUMAN             Reviewed;         358 AA.
AC   O95210; B3KVZ9;
DE   RecName: Full=Starch-binding domain-containing protein 1;
DE   AltName: Full=Genethonin-1;
GN   Name=STBD1; ORFNames=GENX-3414;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:2001070; F:starch binding; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   STC1_HUMAN              Reviewed;         247 AA.
AC   P52823; Q71UE5;
DE   RecName: Full=Stanniocalcin-1;
DE            Short=STC-1;
DE   Flags: Precursor;
GN   Name=STC1; Synonyms=STC;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; TAS:ProtInc.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
//
ID   STC2_HUMAN              Reviewed;         302 AA.
AC   O76061;
DE   RecName: Full=Stanniocalcin-2;
DE            Short=STC-2;
DE   AltName: Full=Stanniocalcin-related protein;
DE            Short=STC-related protein;
DE            Short=STCRP;
DE   Flags: Precursor;
GN   Name=STC2;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0040015; P:negative regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
//
ID   STEA1_HUMAN             Reviewed;         339 AA.
AC   Q9UHE8; A4D1E0; O95034;
DE   RecName: Full=Metalloreductase STEAP1;
DE            EC=1.16.1.-;
DE   AltName: Full=Six-transmembrane epithelial antigen of prostate 1;
GN   Name=STEAP1; Synonyms=PRSS24, STEAP;
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:GOC.
//
ID   STEA2_HUMAN             Reviewed;         490 AA.
AC   Q8NFT2; A4D1F1; G5E9C6; Q6UXN6; Q6YPB1; Q8IUE7;
DE   RecName: Full=Metalloreductase STEAP2;
DE            EC=1.16.1.-;
DE   AltName: Full=Prostate cancer-associated protein 1;
DE   AltName: Full=Protein up-regulated in metastatic prostate cancer;
DE            Short=PUMPCn;
DE   AltName: Full=Six-transmembrane epithelial antigen of prostate 2;
DE   AltName: Full=SixTransMembrane protein of prostate 1;
GN   Name=STEAP2; Synonyms=PCANAP1, STAMP1; ORFNames=UNQ6507/PRO23203;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IDA:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IDA:UniProtKB.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   GO; GO:0045055; P:regulated secretory pathway; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IDA:UniProtKB.
//
ID   STEA3_HUMAN             Reviewed;         488 AA.
AC   Q658P3; A8K6E3; Q4VBR2; Q4ZG36; Q53SQ8; Q7Z389; Q86SF6; Q8NEW6;
AC   Q8TDP3; Q8TF03; Q9NVB5;
DE   RecName: Full=Metalloreductase STEAP3;
DE            EC=1.16.1.-;
DE   AltName: Full=Dudulin-2;
DE   AltName: Full=Six-transmembrane epithelial antigen of prostate 3;
DE   AltName: Full=Tumor suppressor-activated pathway protein 6;
DE            Short=hTSAP6;
DE   AltName: Full=pHyde;
DE            Short=hpHyde;
GN   Name=STEAP3; Synonyms=TSAP6;
DR   GO; GO:0000293; F:ferric-chelate reductase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0009306; P:protein secretion; IMP:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   STEA4_HUMAN             Reviewed;         459 AA.
AC   Q687X5; Q658Q9; Q687X4; Q8WWB0; Q9H5R1;
DE   RecName: Full=Metalloreductase STEAP4;
DE            EC=1.16.1.-;
DE   AltName: Full=Six-transmembrane epithelial antigen of prostate 4;
DE   AltName: Full=SixTransMembrane protein of prostate 2;
DE   AltName: Full=Tumor necrosis factor, alpha-induced protein 9;
GN   Name=STEAP4; Synonyms=STAMP2, TNFAIP9;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
//
ID   STEAL_HUMAN             Reviewed;         245 AA.
AC   Q6NZ63; B5MCI2;
DE   RecName: Full=STEAP family member 1B;
GN   Name=STEAP1B;
//
ID   STF1_HUMAN              Reviewed;         461 AA.
AC   Q13285; O15196; Q5T6F5;
DE   RecName: Full=Steroidogenic factor 1;
DE            Short=SF-1;
DE            Short=STF-1;
DE   AltName: Full=Adrenal 4-binding protein;
DE   AltName: Full=Fushi tarazu factor homolog 1;
DE   AltName: Full=Nuclear receptor subfamily 5 group A member 1;
DE   AltName: Full=Steroid hormone receptor Ad4BP;
GN   Name=NR5A1; Synonyms=AD4BP, FTZF1, SF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005543; F:phospholipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0042445; P:hormone metabolic process; IEA:Ensembl.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; TAS:GOC.
DR   GO; GO:0001553; P:luteinization; IEA:Ensembl.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; TAS:ProtInc.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:2000195; P:negative regulation of female gonad development; IEA:Ensembl.
DR   GO; GO:2000020; P:positive regulation of male gonad development; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0007538; P:primary sex determination; TAS:ProtInc.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0009888; P:tissue development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   STH_HUMAN               Reviewed;         128 AA.
AC   Q8IWL8; A1L3X7;
DE   RecName: Full=Saitohin;
GN   Name=STH;
//
ID   STIL_HUMAN              Reviewed;        1287 AA.
AC   Q15468; Q5T0C5; Q68CN9;
DE   RecName: Full=SCL-interrupting locus protein;
DE   AltName: Full=TAL-1-interrupting locus protein;
GN   Name=STIL; Synonyms=SIL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:BHF-UCL.
DR   GO; GO:0000578; P:embryonic axis specification; ISS:BHF-UCL.
DR   GO; GO:0033504; P:floor plate development; ISS:BHF-UCL.
DR   GO; GO:0030900; P:forebrain development; ISS:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0035264; P:multicellular organism growth; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0001843; P:neural tube closure; ISS:BHF-UCL.
DR   GO; GO:0021915; P:neural tube development; ISS:BHF-UCL.
DR   GO; GO:0030903; P:notochord development; ISS:BHF-UCL.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:BHF-UCL.
//
ID   STIM1_HUMAN             Reviewed;         685 AA.
AC   Q13586; Q8N382;
DE   RecName: Full=Stromal interaction molecule 1;
DE   Flags: Precursor;
GN   Name=STIM1; Synonyms=GOK;
DR   GO; GO:0005246; F:calcium channel regulator activity; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0032237; P:activation of store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0005513; P:detection of calcium ion; IDA:UniProtKB.
DR   GO; GO:0051924; P:regulation of calcium ion transport; IDA:UniProtKB.
DR   GO; GO:2001256; P:regulation of store-operated calcium entry; IEA:Ensembl.
DR   GO; GO:0002115; P:store-operated calcium entry; IEA:Ensembl.
//
ID   STIM2_HUMAN             Reviewed;         746 AA.
AC   Q9P246; Q96BF1; Q9BQH2; Q9H8R1;
DE   RecName: Full=Stromal interaction molecule 2;
DE   Flags: Precursor;
GN   Name=STIM2; Synonyms=KIAA1482;
DR   GO; GO:0005246; F:calcium channel regulator activity; IMP:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0032237; P:activation of store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.
//
ID   STING_HUMAN             Reviewed;         379 AA.
AC   Q86WV6; A8K3P6; B6EB35; D6RBX0; D6RE01; D6RID9;
DE   RecName: Full=Stimulator of interferon genes protein;
DE            Short=hSTING;
DE   AltName: Full=Endoplasmic reticulum interferon stimulator;
DE            Short=ERIS;
DE   AltName: Full=Mediator of IRF3 activation;
DE            Short=hMITA;
DE   AltName: Full=Transmembrane protein 173;
GN   Name=TMEM173; Synonyms=ERIS, MITA, STING;
DR   GO; GO:0035438; F:cyclic-di-GMP binding; IDA:UniProtKB.
DR   GO; GO:0061507; F:cyclic-GMP-AMP binding; ISS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:BHF-UCL.
DR   GO; GO:0002218; P:activation of innate immune response; IMP:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IMP:BHF-UCL.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProtKB.
DR   GO; GO:0032608; P:interferon-beta production; IDA:UniProtKB.
DR   GO; GO:0002230; P:positive regulation of defense response to virus by host; IMP:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IDA:BHF-UCL.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
//
ID   STIP1_HUMAN             Reviewed;         543 AA.
AC   P31948; Q5TZU9;
DE   RecName: Full=Stress-induced-phosphoprotein 1;
DE            Short=STI1;
DE   AltName: Full=Hsc70/Hsp90-organizing protein;
DE            Short=Hop;
DE   AltName: Full=Renal carcinoma antigen NY-REN-11;
DE   AltName: Full=Transformation-sensitive protein IEF SSP 3521;
GN   Name=STIP1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   STK10_HUMAN             Reviewed;         968 AA.
AC   O94804; A6ND35; B2R8F5; B3KMY1; Q6NSK0; Q9UIW4;
DE   RecName: Full=Serine/threonine-protein kinase 10;
DE            EC=2.7.11.1;
DE   AltName: Full=Lymphocyte-oriented kinase;
GN   Name=STK10; Synonyms=LOK;
DR   GuidetoPHARMACOLOGY; 2211; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0042801; F:polo kinase kinase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071593; P:lymphocyte aggregation; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   STK11_HUMAN             Reviewed;         433 AA.
AC   Q15831; B2RBX7; E7EW76;
DE   RecName: Full=Serine/threonine-protein kinase STK11;
DE            EC=2.7.11.1;
DE   AltName: Full=Liver kinase B1;
DE            Short=LKB1;
DE            Short=hLKB1;
DE   AltName: Full=Renal carcinoma antigen NY-REN-19;
DE   Flags: Precursor;
GN   Name=STK11; Synonyms=LKB1, PJS;
DR   GuidetoPHARMACOLOGY; 2212; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:MGI.
DR   GO; GO:0043276; P:anoikis; IMP:BHF-UCL.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0051645; P:Golgi localization; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0045722; P:positive regulation of gluconeogenesis; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; ISS:UniProtKB.
DR   GO; GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.
DR   GO; GO:0051896; P:regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0033762; P:response to glucagon; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
DR   GO; GO:0033993; P:response to lipid; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0036399; P:TCR signalosome assembly; IEA:Ensembl.
DR   GO; GO:0001894; P:tissue homeostasis; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; ISS:UniProtKB.
//
ID   STK16_HUMAN             Reviewed;         305 AA.
AC   O75716; A8K9H9; Q5U0F8; Q96KI2; Q9BUH4; Q9UEN3; Q9UP78;
DE   RecName: Full=Serine/threonine-protein kinase 16;
DE            EC=2.7.11.1;
DE   AltName: Full=Myristoylated and palmitoylated serine/threonine-protein kinase;
DE            Short=MPSK;
DE   AltName: Full=Protein kinase PKL12;
DE   AltName: Full=TGF-beta-stimulated factor 1;
DE            Short=TSF-1;
DE   AltName: Full=Tyrosine-protein kinase STK16;
DE            EC=2.7.10.2;
DE   AltName: Full=hPSK;
GN   Name=STK16; Synonyms=MPSK1, PKL12, TSF1;
DR   GuidetoPHARMACOLOGY; 2213; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
//
ID   STK19_HUMAN             Reviewed;         368 AA.
AC   P49842; A6NF95; A6NFW8; B0QZR5; Q13159; Q31617; Q5JP77; Q5ST72;
AC   Q5ST75;
DE   RecName: Full=Serine/threonine-protein kinase 19;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein G11;
DE   AltName: Full=Protein RP1;
GN   Name=STK19; Synonyms=G11, RP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
//
ID   STK24_HUMAN             Reviewed;         443 AA.
AC   Q9Y6E0; O14840; Q5JV92;
DE   RecName: Full=Serine/threonine-protein kinase 24;
DE            EC=2.7.11.1;
DE   AltName: Full=Mammalian STE20-like protein kinase 3;
DE            Short=MST-3;
DE   AltName: Full=STE20-like kinase MST3;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein kinase 24 36 kDa subunit;
DE     AltName: Full=Mammalian STE20-like protein kinase 3 N-terminal;
DE              Short=MST3/N;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein kinase 24 12 kDa subunit;
DE     AltName: Full=Mammalian STE20-like protein kinase 3 C-terminal;
DE              Short=MST3/C;
GN   Name=STK24; Synonyms=MST3, STK3;
DR   GuidetoPHARMACOLOGY; 2217; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048679; P:regulation of axon regeneration; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   STK25_HUMAN             Reviewed;         426 AA.
AC   O00506; A8K6Z3; A8K7D2; B7Z9K1; Q15522; Q5BJF1;
DE   RecName: Full=Serine/threonine-protein kinase 25;
DE            EC=2.7.11.1;
DE   AltName: Full=Ste20-like kinase;
DE   AltName: Full=Sterile 20/oxidant stress-response kinase 1;
DE            Short=SOK-1;
DE            Short=Ste20/oxidant stress response kinase 1;
GN   Name=STK25; Synonyms=SOK1, YSK1;
DR   GuidetoPHARMACOLOGY; 2218; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; IBA:RefGenome.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0051645; P:Golgi localization; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0045595; P:regulation of cell differentiation; IBA:RefGenome.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   STK31_HUMAN             Reviewed;        1019 AA.
AC   Q9BXU1; B4DZ06; B7WPP5; C9J4F9; Q6PCD3; Q9BXH8;
DE   RecName: Full=Serine/threonine-protein kinase 31;
DE            EC=2.7.11.1;
DE   AltName: Full=Serine/threonine-protein kinase NYD-SPK;
DE   AltName: Full=Sugen kinase 396;
DE            Short=SgK396;
GN   Name=STK31; Synonyms=SGK396;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   STK33_HUMAN             Reviewed;         514 AA.
AC   Q9BYT3; Q658S6; Q8NEF5;
DE   RecName: Full=Serine/threonine-protein kinase 33;
DE            EC=2.7.11.1;
GN   Name=STK33;
DR   GuidetoPHARMACOLOGY; 2221; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
//
ID   STK35_HUMAN             Reviewed;         534 AA.
AC   Q8TDR2; B2RBM3; C7ENV8; Q2NKW6; Q5T3R1; Q5T3R2; Q96AB4; Q9BZ06;
DE   RecName: Full=Serine/threonine-protein kinase 35;
DE            EC=2.7.11.1;
DE   AltName: Full=CLP-36-interacting kinase 1;
DE            Short=CLIK-1;
DE   AltName: Full=PDLIM1-interacting kinase 1;
DE   AltName: Full=Serine/threonine-protein kinase 35 L1;
GN   Name=STK35; Synonyms=CLIK1, PDIK1, STK35L1;
DR   GuidetoPHARMACOLOGY; 2222; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   STK36_HUMAN             Reviewed;        1315 AA.
AC   Q9NRP7; B7WPM3; Q8TC32; Q9H9N9; Q9UF35; Q9ULE2;
DE   RecName: Full=Serine/threonine-protein kinase 36;
DE            EC=2.7.11.1;
DE   AltName: Full=Fused homolog;
GN   Name=STK36; Synonyms=KIAA1278;
DR   GuidetoPHARMACOLOGY; 2223; -.
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IC:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0007228; P:positive regulation of hh target transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
//
ID   STK38_HUMAN             Reviewed;         465 AA.
AC   Q15208; Q503A1;
DE   RecName: Full=Serine/threonine-protein kinase 38;
DE            EC=2.7.11.1;
DE   AltName: Full=NDR1 protein kinase;
DE   AltName: Full=Nuclear Dbf2-related kinase 1;
GN   Name=STK38; Synonyms=NDR1;
DR   GuidetoPHARMACOLOGY; 1517; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   STK39_HUMAN             Reviewed;         545 AA.
AC   Q9UEW8; O14774; Q53S90; Q53SL7; Q53SS1; Q9UER4;
DE   RecName: Full=STE20/SPS1-related proline-alanine-rich protein kinase;
DE            Short=Ste-20-related kinase;
DE            EC=2.7.11.1;
DE   AltName: Full=DCHT;
DE   AltName: Full=Serine/threonine-protein kinase 39;
GN   Name=STK39; Synonyms=SPAK;
DR   GuidetoPHARMACOLOGY; 2224; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; NAS:UniProtKB.
DR   GO; GO:0043268; P:positive regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; NAS:GOC.
//
ID   STK3_HUMAN              Reviewed;         491 AA.
AC   Q13188; A8K722; B3KYA7; Q15445; Q15801; Q96FM6;
DE   RecName: Full=Serine/threonine-protein kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Mammalian STE20-like protein kinase 2;
DE            Short=MST-2;
DE   AltName: Full=STE20-like kinase MST2;
DE   AltName: Full=Serine/threonine-protein kinase Krs-1;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein kinase 3 36kDa subunit;
DE              Short=MST2/N;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein kinase 3 20kDa subunit;
DE              Short=MST2/C;
GN   Name=STK3; Synonyms=KRS1, MST2;
DR   GuidetoPHARMACOLOGY; 2219; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; ISS:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; TAS:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0035329; P:hippo signaling; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   STK40_HUMAN             Reviewed;         435 AA.
AC   Q8N2I9; D3DPS8; Q5VTK8; Q5VTK9; Q6ZMN1; Q8N2J8; Q8N3I6; Q96HN6;
AC   Q96I44; Q9BSA3; Q9H7H6;
DE   RecName: Full=Serine/threonine-protein kinase 40;
DE            EC=2.7.11.1;
DE   AltName: Full=SINK-homologous serine/threonine-protein kinase;
DE   AltName: Full=Sugen kinase 495;
DE            Short=SgK495;
GN   Name=STK40; Synonyms=SGK495, SHIK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
//
ID   STK4_HUMAN              Reviewed;         487 AA.
AC   Q13043; B2RCR8; Q15802; Q4G156; Q5H982; Q6PD60; Q9BR32; Q9NTZ4;
DE   RecName: Full=Serine/threonine-protein kinase 4;
DE            EC=2.7.11.1;
DE   AltName: Full=Mammalian STE20-like protein kinase 1;
DE            Short=MST-1;
DE   AltName: Full=STE20-like kinase MST1;
DE   AltName: Full=Serine/threonine-protein kinase Krs-2;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein kinase 4 37kDa subunit;
DE              Short=MST1/N;
DE   Contains:
DE     RecName: Full=Serine/threonine-protein kinase 4 18kDa subunit;
DE              Short=MST1/C;
GN   Name=STK4; Synonyms=KRS2, MST1;
DR   GuidetoPHARMACOLOGY; 2225; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:MGI.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; TAS:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060706; P:cell differentiation involved in embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IDA:MGI.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0003157; P:endocardium development; IEA:Ensembl.
DR   GO; GO:0097284; P:hepatocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; TAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; TAS:GOC.
DR   GO; GO:0060215; P:primitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:MGI.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IBA:GOC.
//
ID   STMD1_HUMAN             Reviewed;         276 AA.
AC   H3BQB6;
DE   RecName: Full=Stathmin domain-containing protein 1;
GN   Name=STMND1;
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro.
//
ID   STML1_HUMAN             Reviewed;         398 AA.
AC   Q9UBI4; B3KQN0; B4DUU5; B4DXM9; E7ESC0; H3BRP3; O95675; Q4PNR4;
AC   Q6FGL8; Q8WYI7; Q9UMB9; Q9UMC0; Q9Y6H9;
DE   RecName: Full=Stomatin-like protein 1;
DE            Short=SLP-1;
DE   AltName: Full=EPB72-like protein 1;
DE   AltName: Full=Protein unc-24 homolog;
DE   AltName: Full=Stomatin-related protein;
DE            Short=STORP;
GN   Name=STOML1; Synonyms=SLP1, UNC24; ORFNames=MSTP019;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032934; F:sterol binding; IEA:InterPro.
//
ID   STML3_HUMAN             Reviewed;         291 AA.
AC   Q8TAV4; B4E285; Q5JS35;
DE   RecName: Full=Stomatin-like protein 3;
DE            Short=SLP-3;
GN   Name=STOML3;
DR   GO; GO:0007165; P:signal transduction; IEA:Ensembl.
//
ID   STML2_HUMAN             Reviewed;         356 AA.
AC   Q9UJZ1; B4E1K7; D3DRN3; O60376; Q53G29; Q96FY2; Q9P042;
DE   RecName: Full=Stomatin-like protein 2, mitochondrial;
DE            Short=SLP-2;
DE   AltName: Full=EPB72-like protein 2;
DE   AltName: Full=Paraprotein target 7;
DE            Short=Paratarg-7;
DE   Flags: Precursor;
GN   Name=STOML2; Synonyms=SLP2; ORFNames=HSPC108;
DR   GO; GO:1901612; F:cardiolipin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0035710; P:CD4-positive, alpha-beta T cell activation; ISS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0032623; P:interleukin-2 production; ISS:UniProtKB.
DR   GO; GO:0010876; P:lipid localization; ISS:UniProtKB.
DR   GO; GO:0042776; P:mitochondrial ATP synthesis coupled proton transport; IMP:UniProtKB.
DR   GO; GO:0006851; P:mitochondrial calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0034982; P:mitochondrial protein processing; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
DR   GO; GO:1900210; P:positive regulation of cardiolipin metabolic process; IMP:UniProtKB.
DR   GO; GO:0090297; P:positive regulation of mitochondrial DNA replication; IMP:UniProtKB.
DR   GO; GO:0010918; P:positive regulation of mitochondrial membrane potential; IMP:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:1990046; P:stress-induced mitochondrial fusion; ISS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.
//
ID   STMN1_HUMAN             Reviewed;         149 AA.
AC   P16949; A2A2D1; B2R4E7; B7Z8N4; D3DPJ5;
DE   RecName: Full=Stathmin;
DE   AltName: Full=Leukemia-associated phosphoprotein p18;
DE   AltName: Full=Metablastin;
DE   AltName: Full=Oncoprotein 18;
DE            Short=Op18;
DE   AltName: Full=Phosphoprotein p19;
DE            Short=pp19;
DE   AltName: Full=Prosolin;
DE   AltName: Full=Protein Pr22;
DE   AltName: Full=pp17;
GN   Name=STMN1; Synonyms=C1orf215, LAP18, OP18;
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0015631; F:tubulin binding; IDA:MGI.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0007019; P:microtubule depolymerization; IDA:MGI.
DR   GO; GO:0007052; P:mitotic spindle organization; IDA:MGI.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IEA:Ensembl.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   STMN2_HUMAN             Reviewed;         179 AA.
AC   Q93045; A8K9M2; G3V110; O14952; Q6PK68;
DE   RecName: Full=Stathmin-2;
DE   AltName: Full=Superior cervical ganglion-10 protein;
DE            Short=Protein SCG10;
GN   Name=STMN2; Synonyms=SCG10, SCGN10;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:1990090; P:cellular response to nerve growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0031117; P:positive regulation of microtubule depolymerization; IDA:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.
//
ID   STMN3_HUMAN             Reviewed;         180 AA.
AC   Q9NZ72; B3KSQ5; B7WP52; O75527; Q969Y4;
DE   RecName: Full=Stathmin-3;
DE   AltName: Full=SCG10-like protein;
GN   Name=STMN3; Synonyms=SCLIP;
DR   GO; GO:0019904; F:protein domain specific binding; ISS:HGNC.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; ISS:HGNC.
DR   GO; GO:0035021; P:negative regulation of Rac protein signal transduction; ISS:HGNC.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0031175; P:neuron projection development; ISS:HGNC.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; ISS:HGNC.
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; ISS:HGNC.
//
ID   STMN4_HUMAN             Reviewed;         189 AA.
AC   Q9H169; D3DSS8; D3DSS9; Q2TAB9;
DE   RecName: Full=Stathmin-4;
DE   AltName: Full=Stathmin-like protein B3;
DE            Short=RB3;
GN   Name=STMN4;
DR   GO; GO:0031110; P:regulation of microtubule polymerization or depolymerization; IEA:InterPro.
//
ID   STN1_HUMAN              Reviewed;         368 AA.
AC   Q9H668; D3DR99; Q5TCZ0;
DE   RecName: Full=CST complex subunit STN1;
DE   AltName: Full=Oligonucleotide/oligosaccharide-binding fold-containing protein 1;
DE   AltName: Full=Suppressor of cdc thirteen homolog;
GN   Name=OBFC1; Synonyms=STN1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
DR   GO; GO:0043047; F:single-stranded telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0045740; P:positive regulation of DNA replication; ISS:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0010833; P:telomere maintenance via telomere lengthening; IMP:UniProtKB.
//
ID   STOM_HUMAN              Reviewed;         288 AA.
AC   P27105; B1AM77; Q14087; Q15609; Q5VX96; Q96FK4;
DE   RecName: Full=Erythrocyte band 7 integral membrane protein;
DE   AltName: Full=Protein 7.2b;
DE   AltName: Full=Stomatin;
GN   Name=STOM; Synonyms=BND7, EPB72;
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   STON2_HUMAN             Reviewed;         905 AA.
AC   Q8WXE9; G3V2T7; Q17R24; Q59H11; Q6NT47; Q96RI7; Q96RU6;
DE   RecName: Full=Stonin-2;
DE   AltName: Full=Stoned B;
GN   Name=STON2; Synonyms=STN2, STNB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; IGI:UniProtKB.
//
ID   STON1_HUMAN             Reviewed;         735 AA.
AC   Q9Y6Q2; A8MXJ1; B5MCF5; B7ZL16; Q96JE3; Q9BYX3;
DE   RecName: Full=Stonin-1;
DE   AltName: Full=Stoned B-like factor;
GN   Name=STON1; Synonyms=SALF, SBLF, STN1;
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0030100; P:regulation of endocytosis; IDA:UniProtKB.
//
ID   STOX1_HUMAN             Reviewed;         989 AA.
AC   Q6ZVD7; A2A3Q9; A5D6Y7; B0QZA4; B0QZA5; B0QZA6; Q4F8Q6; Q5I946;
AC   Q5I947; Q5I948; Q5VX38; Q5VX39; Q6ZRY3; Q96LR3; Q96LS0;
DE   RecName: Full=Storkhead-box protein 1;
DE   AltName: Full=Winged-helix domain-containing protein;
GN   Name=STOX1; Synonyms=C10orf24;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   STOX2_HUMAN             Reviewed;         926 AA.
AC   Q9P2F5; A6H8U4; Q9NPS8;
DE   RecName: Full=Storkhead-box protein 2;
GN   Name=STOX2; Synonyms=KIAA1392;
DR   GO; GO:0009790; P:embryo development; IEP:UniProtKB.
DR   GO; GO:0001893; P:maternal placenta development; IEP:UniProtKB.
//
ID   STP1_HUMAN              Reviewed;          55 AA.
AC   P09430;
DE   RecName: Full=Spermatid nuclear transition protein 1;
DE            Short=STP-1;
DE            Short=TP-1;
GN   Name=TNP1;
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0006342; P:chromatin silencing; IEP:UniProtKB.
DR   GO; GO:0035042; P:fertilization, exchange of chromosomal proteins; TAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006337; P:nucleosome disassembly; IMP:UniProtKB.
DR   GO; GO:0019953; P:sexual reproduction; IMP:UniProtKB.
DR   GO; GO:0000012; P:single strand break repair; IDA:UniProtKB.
DR   GO; GO:0030317; P:sperm motility; IMP:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; IDA:UniProtKB.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; TAS:UniProtKB.
DR   GO; GO:0007290; P:spermatid nucleus elongation; IMP:UniProtKB.
//
ID   STP2_HUMAN              Reviewed;         138 AA.
AC   Q05952; Q9NZB0;
DE   RecName: Full=Nuclear transition protein 2;
DE            Short=TP-2;
DE            Short=TP2;
GN   Name=TNP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007341; P:penetration of zona pellucida; IEA:Ensembl.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   STPAP_HUMAN             Reviewed;         874 AA.
AC   Q9H6E5; A1A527; A8K995; Q2NL65; Q7L583; Q9H6H7;
DE   RecName: Full=Speckle targeted PIP5K1A-regulated poly(A) polymerase;
DE            Short=Star-PAP;
DE            EC=2.7.7.19;
DE   AltName: Full=RNA-binding motif protein 21;
DE            Short=RNA-binding protein 21;
DE   AltName: Full=U6 snRNA-specific terminal uridylyltransferase 1;
DE            Short=U6-TUTase;
DE            EC=2.7.7.52;
GN   Name=TUT1; Synonyms=RBM21;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:UniProtKB.
DR   GO; GO:0004652; F:polynucleotide adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0050265; F:RNA uridylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0006379; P:mRNA cleavage; IDA:UniProtKB.
DR   GO; GO:0006378; P:mRNA polyadenylation; IDA:UniProtKB.
DR   GO; GO:0016180; P:snRNA processing; IMP:UniProtKB.
//
ID   STPG1_HUMAN             Reviewed;         334 AA.
AC   Q5TH74; Q49AP0; Q6P3R4; Q86VU9; Q8WVQ3;
DE   RecName: Full=O(6)-methylguanine-induced apoptosis 2;
DE            Short=MAPO2;
DE   AltName: Full=Sperm-tail PG-rich repeat-containing protein 1;
GN   Name=STPG1; Synonyms=C1orf201;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   STPG2_HUMAN             Reviewed;         459 AA.
AC   Q8N412;
DE   RecName: Full=Sperm-tail PG-rich repeat-containing protein 2;
GN   Name=STPG2; Synonyms=C4orf37;
//
ID   STRA6_HUMAN             Reviewed;         667 AA.
AC   Q9BX79; A8K7F1; B7Z5M9; B7Z862; D3DW54; F5GYI8; I3L1G8; Q6PJF8;
AC   Q71RB9; Q7L9G1; Q7Z3U9; Q8TB21; Q9BX78; Q9H9U8;
DE   RecName: Full=Stimulated by retinoic acid gene 6 protein homolog;
GN   Name=STRA6; ORFNames=PP14296, UNQ3126/PRO10282/PRO19578;
DR   GO; GO:0004872; F:receptor activity; IEA:InterPro.
DR   GO; GO:0051183; F:vitamin transporter activity; IEA:InterPro.
DR   GO; GO:0030325; P:adrenal gland development; IMP:DFLAT.
DR   GO; GO:0061143; P:alveolar primary septum development; IMP:DFLAT.
DR   GO; GO:0048844; P:artery morphogenesis; IMP:DFLAT.
DR   GO; GO:0001568; P:blood vessel development; IMP:DFLAT.
DR   GO; GO:0050890; P:cognition; IMP:DFLAT.
DR   GO; GO:0048589; P:developmental growth; IMP:DFLAT.
DR   GO; GO:0060539; P:diaphragm development; IMP:DFLAT.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IMP:DFLAT.
DR   GO; GO:0097070; P:ductus arteriosus closure; IMP:DFLAT.
DR   GO; GO:0043583; P:ear development; IMP:DFLAT.
DR   GO; GO:0060900; P:embryonic camera-type eye formation; IMP:DFLAT.
DR   GO; GO:0048566; P:embryonic digestive tract development; IMP:DFLAT.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; IMP:DFLAT.
DR   GO; GO:0060325; P:face morphogenesis; IMP:DFLAT.
DR   GO; GO:0007631; P:feeding behavior; IMP:DFLAT.
DR   GO; GO:0030540; P:female genitalia development; IMP:DFLAT.
DR   GO; GO:0060322; P:head development; IMP:DFLAT.
DR   GO; GO:0060323; P:head morphogenesis; IMP:DFLAT.
DR   GO; GO:0007507; P:heart development; IMP:DFLAT.
DR   GO; GO:0001822; P:kidney development; IMP:DFLAT.
DR   GO; GO:0007612; P:learning; IMP:DFLAT.
DR   GO; GO:0048286; P:lung alveolus development; IMP:DFLAT.
DR   GO; GO:0030324; P:lung development; IMP:DFLAT.
DR   GO; GO:0060426; P:lung vasculature development; IMP:DFLAT.
DR   GO; GO:0050905; P:neuromuscular process; IMP:DFLAT.
DR   GO; GO:0043585; P:nose morphogenesis; IMP:DFLAT.
DR   GO; GO:0061205; P:paramesonephric duct development; IMP:DFLAT.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0048520; P:positive regulation of behavior; IMP:DFLAT.
DR   GO; GO:0061156; P:pulmonary artery morphogenesis; IMP:DFLAT.
DR   GO; GO:0003184; P:pulmonary valve morphogenesis; IMP:DFLAT.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0048745; P:smooth muscle tissue development; IMP:DFLAT.
DR   GO; GO:0061038; P:uterus morphogenesis; IMP:DFLAT.
DR   GO; GO:0003281; P:ventricular septum development; IMP:DFLAT.
DR   GO; GO:0071939; P:vitamin A import; IEA:Ensembl.
DR   GO; GO:0042297; P:vocal learning; IMP:DFLAT.
//
ID   STRA8_HUMAN             Reviewed;         330 AA.
AC   Q7Z7C7;
DE   RecName: Full=Stimulated by retinoic acid gene 8 protein homolog;
GN   Name=STRA8;
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0007066; P:female meiosis sister chromatid cohesion; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0010032; P:meiotic chromosome condensation; IEA:Ensembl.
DR   GO; GO:0042138; P:meiotic DNA double-strand break formation; IEA:Ensembl.
DR   GO; GO:0033315; P:meiotic DNA replication checkpoint; IEA:Ensembl.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; IEA:Ensembl.
DR   GO; GO:0046620; P:regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0007129; P:synapsis; IEA:Ensembl.
//
ID   STRAA_HUMAN             Reviewed;         431 AA.
AC   Q7RTN6; B4DDE3; B4DW17; J3KTC9; Q5JPI2; Q7Z4K9; Q8NC31; Q8NCF1;
AC   Q9H272;
DE   RecName: Full=STE20-related kinase adapter protein alpha;
DE            Short=STRAD alpha;
DE   AltName: Full=STE20-related adapter protein;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-96;
GN   Name=STRADA; Synonyms=LYK5, STRAD;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
//
ID   STRAB_HUMAN             Reviewed;         418 AA.
AC   Q9C0K7; Q5BKY7; Q9P1L0;
DE   RecName: Full=STE20-related kinase adapter protein beta;
DE            Short=STRAD beta;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein;
DE   AltName: Full=CALS-21;
DE   AltName: Full=ILP-interacting protein;
DE   AltName: Full=Pseudokinase ALS2CR2;
GN   Name=STRADB; Synonyms=ALS2CR2, ILPIP; ORFNames=PRO1038;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
//
ID   STRAP_HUMAN             Reviewed;         350 AA.
AC   Q9Y3F4; B2R5S5; Q5TZT4; Q9NTK0; Q9UQC8;
DE   RecName: Full=Serine-threonine kinase receptor-associated protein;
DE   AltName: Full=MAP activator with WD repeats;
DE   AltName: Full=UNR-interacting protein;
DE   AltName: Full=WD-40 repeat protein PT-WD;
GN   Name=STRAP; Synonyms=MAWD, UNRIP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProt.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IMP:UniProt.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:UniProt.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:UniProt.
DR   GO; GO:0060394; P:negative regulation of pathway-restricted SMAD protein phosphorylation; IMP:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:UniProt.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IDA:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   STRBP_HUMAN             Reviewed;         672 AA.
AC   Q96SI9; Q32NB9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4;
DE   RecName: Full=Spermatid perinuclear RNA-binding protein;
GN   Name=STRBP; Synonyms=SPNR;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; IEA:Ensembl.
DR   GO; GO:0007638; P:mechanosensory behavior; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
//
ID   STRCL_HUMAN             Reviewed;        1772 AA.
AC   A6NGW2;
DE   RecName: Full=Putative stereocilin-like protein;
DE   AltName: Full=Stereocilin pseudogene 1;
DE   Flags: Precursor;
GN   Name=STRCP1; Synonyms=STRCP;
//
ID   STRC_HUMAN              Reviewed;        1775 AA.
AC   Q7RTU9;
DE   RecName: Full=Stereocilin;
DE   Flags: Precursor;
GN   Name=STRC;
DR   GO; GO:0060088; P:auditory receptor cell stereocilium organization; ISS:UniProtKB.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
//
ID   STRN3_HUMAN             Reviewed;         797 AA.
AC   Q13033; A2RTX7; A6NHZ7; Q9NRA5;
DE   RecName: Full=Striatin-3;
DE   AltName: Full=Cell cycle autoantigen SG2NA;
DE   AltName: Full=S/G2 antigen;
GN   Name=STRN3; Synonyms=GS2NA, SG2NA;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032355; P:response to estradiol; ISS:UniProtKB.
//
ID   STRN4_HUMAN             Reviewed;         753 AA.
AC   Q9NRL3; Q8NE53;
DE   RecName: Full=Striatin-4;
DE   AltName: Full=Zinedin;
GN   Name=STRN4; Synonyms=ZIN;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
//
ID   STRN_HUMAN              Reviewed;         780 AA.
AC   O43815; Q3KP65; Q53TQ8; Q9NP38;
DE   RecName: Full=Striatin;
GN   Name=STRN;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; ISS:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
DR   GO; GO:0016358; P:dendrite development; ISS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; NAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:UniProtKB.
//
ID   STRP1_HUMAN             Reviewed;         837 AA.
AC   Q5VSL9; Q0V925; Q5VSL8; Q658K2; Q6ZV31; Q8N598; Q96SN2; Q9C0A2;
DE   RecName: Full=Striatin-interacting protein 1;
DE   AltName: Full=Protein FAM40A;
GN   Name=STRIP1; Synonyms=FAM40A, KIAA1761;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   STRP2_HUMAN             Reviewed;         834 AA.
AC   Q9ULQ0; Q8WUZ4;
DE   RecName: Full=Striatin-interacting protein 2;
DE   AltName: Full=Protein FAM40B;
GN   Name=STRIP2; Synonyms=FAM40B, KIAA1170;
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   STRUM_HUMAN             Reviewed;        1159 AA.
AC   Q12768; A8K4R7; Q3KQX5; Q8TBQ2;
DE   RecName: Full=WASH complex subunit strumpellin;
DE   AltName: Full=Strumpellin;
GN   Name=KIAA0196;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; IEA:Ensembl.
//
ID   STS_HUMAN               Reviewed;         583 AA.
AC   P08842; B2RA47;
DE   RecName: Full=Steryl-sulfatase;
DE            EC=3.1.6.2;
DE   AltName: Full=Arylsulfatase C;
DE            Short=ASC;
DE   AltName: Full=Steroid sulfatase;
DE   AltName: Full=Steryl-sulfate sulfohydrolase;
DE   Flags: Precursor;
GN   Name=STS; Synonyms=ARSC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004773; F:steryl-sulfatase activity; TAS:Reactome.
DR   GO; GO:0008484; F:sulfuric ester hydrolase activity; IDA:MGI.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; IEA:UniProtKB-KW.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0006706; P:steroid catabolic process; TAS:ProtInc.
//
ID   STT3A_HUMAN             Reviewed;         705 AA.
AC   P46977; Q86XU9; Q8TE35; Q8WUB4;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A;
DE            Short=Oligosaccharyl transferase subunit STT3A;
DE            Short=STT3-A;
DE            EC=2.4.99.18;
DE   AltName: Full=B5;
DE   AltName: Full=Integral membrane protein 1;
DE   AltName: Full=Transmembrane protein TMC;
GN   Name=STT3A; Synonyms=ITM1, TMC;
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043686; P:co-translational protein modification; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
//
ID   STT3B_HUMAN             Reviewed;         826 AA.
AC   Q8TCJ2; Q96JZ4; Q96KY7;
DE   RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B;
DE            Short=Oligosaccharyl transferase subunit STT3B;
DE            Short=STT3-B;
DE            EC=2.4.99.18;
DE   AltName: Full=Source of immunodominant MHC-associated peptides homolog;
GN   Name=STT3B; Synonyms=SIMP;
DR   GO; GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IMP:UniProtKB.
DR   GO; GO:0043686; P:co-translational protein modification; IMP:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006516; P:glycoprotein catabolic process; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; IMP:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IMP:UniProtKB.
//
ID   STUM_HUMAN              Reviewed;         141 AA.
AC   Q69YW2; A6NGL2;
DE   RecName: Full=Protein stum homolog;
GN   Name=C1orf95;
//
ID   STX10_HUMAN             Reviewed;         249 AA.
AC   O60499; A6NC41; Q6IAP4; Q96AE8;
DE   RecName: Full=Syntaxin-10;
DE            Short=Syn10;
GN   Name=STX10; Synonyms=SYN10;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0048193; P:Golgi vesicle transport; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   STX12_HUMAN             Reviewed;         276 AA.
AC   Q86Y82; B1AJQ7; O95564;
DE   RecName: Full=Syntaxin-12;
GN   Name=STX12;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0033344; P:cholesterol efflux; IDA:BHF-UCL.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IBA:RefGenome.
//
ID   STX11_HUMAN             Reviewed;         287 AA.
AC   O75558; E1P598; O75378; O95148; Q5TCL6;
DE   RecName: Full=Syntaxin-11;
GN   Name=STX11;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; TAS:ProtInc.
DR   GO; GO:0043316; P:cytotoxic T cell degranulation; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0043320; P:natural killer cell degranulation; IEA:Ensembl.
DR   GO; GO:0043312; P:neutrophil degranulation; IEA:Ensembl.
//
ID   STX16_HUMAN             Reviewed;         325 AA.
AC   O14662; A6NK32; A6NN69; A8MPP0; B7ZBN1; B7ZBN2; B7ZBN3; E1P5M0;
AC   E1P607; O14661; O14663; O60517; Q5W084; Q5W086; Q5W087; Q5XKI6;
AC   Q6GMS8; Q9H0Z0; Q9H1T7; Q9H1T8; Q9UIX5;
DE   RecName: Full=Syntaxin-16;
DE            Short=Syn16;
GN   Name=STX16;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:HGNC.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB.
//
ID   STX17_HUMAN             Reviewed;         302 AA.
AC   P56962; Q4VXC2;
DE   RecName: Full=Syntaxin-17;
GN   Name=STX17;
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IMP:UniProtKB.
DR   GO; GO:0000149; F:SNARE binding; IDA:UniProtKB.
DR   GO; GO:0000046; P:autophagic vacuole fusion; IMP:UniProtKB.
DR   GO; GO:0097111; P:endoplasmic reticulum-Golgi intermediate compartment organization; IMP:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IBA:RefGenome.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
//
ID   STX18_HUMAN             Reviewed;         335 AA.
AC   Q9P2W9; Q596L3; Q5TZP5;
DE   RecName: Full=Syntaxin-18;
DE   AltName: Full=Cell growth-inhibiting gene 9 protein;
GN   Name=STX18; ORFNames=GIG9;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   STX19_HUMAN             Reviewed;         294 AA.
AC   Q8N4C7;
DE   RecName: Full=Syntaxin-19;
GN   Name=STX19;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   STX1A_HUMAN             Reviewed;         288 AA.
AC   Q16623; O15447; O15448; Q12936; Q75MD9; Q9BPZ6;
DE   RecName: Full=Syntaxin-1A;
DE   AltName: Full=Neuron-specific antigen HPC-1;
GN   Name=STX1A; Synonyms=STX1;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0001956; P:positive regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:UniProtKB.
DR   GO; GO:0009629; P:response to gravity; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016081; P:synaptic vesicle docking involved in exocytosis; IEA:Ensembl.
//
ID   STX1B_HUMAN             Reviewed;         288 AA.
AC   P61266; Q15531; Q2VPS2;
DE   RecName: Full=Syntaxin-1B;
DE   AltName: Full=Syntaxin-1B1;
DE   AltName: Full=Syntaxin-1B2;
GN   Name=STX1B; Synonyms=STX1B1, STX1B2;
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; TAS:ProtInc.
DR   GO; GO:0005234; F:extracellular-glutamate-gated ion channel activity; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0017157; P:regulation of exocytosis; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:Ensembl.
//
ID   STX2_HUMAN              Reviewed;         288 AA.
AC   P32856; Q86VW8;
DE   RecName: Full=Syntaxin-2;
DE   AltName: Full=Epimorphin;
GN   Name=STX2; Synonyms=EPIM, STX2A, STX2B, STX2C;
DR   GO; GO:0048306; F:calcium-dependent protein binding; ISS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007340; P:acrosome reaction; ISS:HGNC.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   STX3_HUMAN              Reviewed;         289 AA.
AC   Q13277; B4DME0; O43750; O43751; Q15360;
DE   RecName: Full=Syntaxin-3;
GN   Name=STX3; Synonyms=STX3A;
DR   GO; GO:0050544; F:arachidonic acid binding; ISS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061025; P:membrane fusion; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; ISS:HGNC.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
//
ID   STX4_HUMAN              Reviewed;         297 AA.
AC   Q12846; A8MXY0; Q15525; Q6FHE8;
DE   RecName: Full=Syntaxin-4;
DE   AltName: Full=Renal carcinoma antigen NY-REN-31;
GN   Name=STX4; Synonyms=STX4A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   STX5_HUMAN              Reviewed;         355 AA.
AC   Q13190; B2R8T2; F8W8Q9; Q5U0D4; Q7Z3T6; Q9BUG1;
DE   RecName: Full=Syntaxin-5;
GN   Name=STX5; Synonyms=STX5A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:HGNC.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:HGNC.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0006903; P:vesicle targeting; TAS:ProtInc.
//
ID   STX6_HUMAN              Reviewed;         255 AA.
AC   O43752; B2R652; B4DR17; Q5VY08; Q6FH83;
DE   RecName: Full=Syntaxin-6;
GN   Name=STX6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0007032; P:endosome organization; IEA:Ensembl.
DR   GO; GO:0048193; P:Golgi vesicle transport; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
DR   GO; GO:0006906; P:vesicle fusion; IPI:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:Ensembl.
//
ID   STX7_HUMAN              Reviewed;         261 AA.
AC   O15400; E1P579; Q5SZW2; Q96ES9;
DE   RecName: Full=Syntaxin-7;
GN   Name=STX7;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:ProtInc.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IBA:RefGenome.
//
ID   STX8_HUMAN              Reviewed;         236 AA.
AC   Q9UNK0; O60712; Q53XT8;
DE   RecName: Full=Syntaxin-8;
GN   Name=STX8;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0008333; P:endosome to lysosome transport; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   STXB1_HUMAN             Reviewed;         594 AA.
AC   P61764; B1AM97; Q28208; Q62759; Q64320; Q96TG8;
DE   RecName: Full=Syntaxin-binding protein 1;
DE   AltName: Full=MUNC18-1;
DE   AltName: Full=N-Sec1;
DE   AltName: Full=Protein unc-18 homolog 1;
DE            Short=Unc18-1;
DE   AltName: Full=Protein unc-18 homolog A;
DE            Short=Unc-18A;
DE   AltName: Full=p67;
GN   Name=STXBP1; Synonyms=UNC18A;
DR   GO; GO:0042802; F:identical protein binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000149; F:SNARE binding; ISS:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; IPI:UniProtKB.
DR   GO; GO:0017075; F:syntaxin-1 binding; ISS:UniProtKB.
DR   GO; GO:0007412; P:axon target recognition; ISS:UniProtKB.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0060292; P:long term synaptic depression; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032229; P:negative regulation of synaptic transmission, GABAergic; ISS:UniProtKB.
DR   GO; GO:0007274; P:neuromuscular synaptic transmission; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IMP:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; IMP:UniProtKB.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0010807; P:regulation of synaptic vesicle priming; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016188; P:synaptic vesicle maturation; ISS:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:Ensembl.
//
ID   STXB2_HUMAN             Reviewed;         593 AA.
AC   Q15833; Q9BU65;
DE   RecName: Full=Syntaxin-binding protein 2;
DE   AltName: Full=Protein unc-18 homolog 2;
DE            Short=Unc18-2;
DE   AltName: Full=Protein unc-18 homolog B;
DE            Short=Unc-18B;
GN   Name=STXBP2; Synonyms=UNC18B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030348; F:syntaxin-3 binding; IPI:UniProtKB.
DR   GO; GO:0001909; P:leukocyte mediated cytotoxicity; IMP:UniProtKB.
DR   GO; GO:0043312; P:neutrophil degranulation; IEP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   STXB3_HUMAN             Reviewed;         592 AA.
AC   O00186; A8K269; A8K5K7; Q53FW1; Q86YJ3; Q9UPD7;
DE   RecName: Full=Syntaxin-binding protein 3;
DE   AltName: Full=Platelet Sec1 protein;
DE            Short=PSP;
DE   AltName: Full=Protein unc-18 homolog 3;
DE            Short=Unc18-3;
DE   AltName: Full=Protein unc-18 homolog C;
DE            Short=Unc-18C;
GN   Name=STXBP3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019905; F:syntaxin binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.
DR   GO; GO:0043312; P:neutrophil degranulation; IEP:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IMP:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   STXB4_HUMAN             Reviewed;         553 AA.
AC   Q6ZWJ1; Q8IVZ5;
DE   RecName: Full=Syntaxin-binding protein 4;
DE   AltName: Full=Syntaxin 4-interacting protein;
DE            Short=STX4-interacting protein;
DE            Short=Synip;
GN   Name=STXBP4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
//
ID   STXB5_HUMAN             Reviewed;        1151 AA.
AC   Q5T5C0; Q14DF3; Q5T5C1; Q5T5C2; Q8NBG8; Q96NG9;
DE   RecName: Full=Syntaxin-binding protein 5;
DE   AltName: Full=Lethal(2) giant larvae protein homolog 3;
DE   AltName: Full=Tomosyn-1;
GN   Name=STXBP5; Synonyms=LLGL3;
DR   GO; GO:0017075; F:syntaxin-1 binding; ISS:BHF-UCL.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045921; P:positive regulation of exocytosis; ISS:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   STXB6_HUMAN             Reviewed;         210 AA.
AC   Q8NFX7; D3DS78; Q8N3H1; Q8N8D5; Q96GF3; Q9P008;
DE   RecName: Full=Syntaxin-binding protein 6;
DE   AltName: Full=Amisyn;
GN   Name=STXBP6; ORFNames=HSPC156;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   STYK1_HUMAN             Reviewed;         422 AA.
AC   Q6J9G0; B2R9T2; Q52LR3; Q9BXY2; Q9NSH1;
DE   RecName: Full=Tyrosine-protein kinase STYK1;
DE            EC=2.7.10.2;
DE   AltName: Full=Novel oncogene with kinase domain;
DE   AltName: Full=Protein PK-unique;
DE   AltName: Full=Serine/threonine/tyrosine kinase 1;
GN   Name=STYK1; Synonyms=NOK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   STYX_HUMAN              Reviewed;         223 AA.
AC   Q8WUJ0; B9EJG0; Q99850;
DE   RecName: Full=Serine/threonine/tyrosine-interacting protein;
DE   AltName: Full=Protein tyrosine phosphatase-like protein;
GN   Name=STYX;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IBA:RefGenome.
//
ID   STYL1_HUMAN             Reviewed;         313 AA.
AC   Q9Y6J8; Q9UBP1; Q9UK06; Q9UK07; Q9UKG2; Q9UKG3;
DE   RecName: Full=Serine/threonine/tyrosine-interacting-like protein 1;
DE   AltName: Full=Dual specificity phosphatase inhibitor MK-STYX;
DE   AltName: Full=Dual specificity protein phosphatase 24;
DE   AltName: Full=Map kinase phosphatase-like protein MK-STYX;
GN   Name=STYXL1; Synonyms=DUSP24, MKSTYX;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
//
ID   SUCA_HUMAN              Reviewed;         346 AA.
AC   P53597; Q9BWB0; Q9UNP6;
DE   RecName: Full=Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial;
DE            EC=6.2.1.4;
DE            EC=6.2.1.5;
DE   AltName: Full=Succinyl-CoA synthetase subunit alpha;
DE            Short=SCS-alpha;
DE   Flags: Precursor;
GN   Name=SUCLG1;
DR   GO; GO:0003878; F:ATP citrate synthase activity; IEA:InterPro.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004776; F:succinate-CoA ligase (GDP-forming) activity; IEA:UniProtKB-EC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006105; P:succinate metabolic process; IEA:Ensembl.
DR   GO; GO:0006104; P:succinyl-CoA metabolic process; IEA:Ensembl.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   SUCB1_HUMAN             Reviewed;         463 AA.
AC   Q9P2R7; B2RDE7; O95194; Q5T9Q4; Q5T9Q6; Q9NV21; Q9NVP7;
DE   RecName: Full=Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial;
DE            EC=6.2.1.5;
DE   AltName: Full=ATP-specific succinyl-CoA synthetase subunit beta;
DE   AltName: Full=Renal carcinoma antigen NY-REN-39;
DE   AltName: Full=Succinyl-CoA synthetase beta-A chain;
DE            Short=SCS-betaA;
DE   Flags: Precursor;
GN   Name=SUCLA2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; TAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006105; P:succinate metabolic process; IEA:Ensembl.
DR   GO; GO:0006104; P:succinyl-CoA metabolic process; TAS:ProtInc.
DR   GO; GO:0006781; P:succinyl-CoA pathway; NAS:UniProtKB.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   SUCB2_HUMAN             Reviewed;         432 AA.
AC   Q96I99; C9JVT2; O95195; Q6NUH7; Q86VX8; Q8WUQ1;
DE   RecName: Full=Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial;
DE            EC=6.2.1.4;
DE   AltName: Full=GTP-specific succinyl-CoA synthetase subunit beta;
DE   AltName: Full=Succinyl-CoA synthetase beta-G chain;
DE            Short=SCS-betaG;
DE   Flags: Precursor;
GN   Name=SUCLG2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0019003; F:GDP binding; IEA:Ensembl.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004776; F:succinate-CoA ligase (GDP-forming) activity; NAS:UniProtKB.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006105; P:succinate metabolic process; IEA:Ensembl.
DR   GO; GO:0006104; P:succinyl-CoA metabolic process; NAS:UniProtKB.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
//
ID   SUCHY_HUMAN             Reviewed;         445 AA.
AC   Q9HAC7; A4D1W5; B4DR73; Q4KMW4; Q4KMW8; Q4KMZ0; Q8TE00; Q8TEY1;
DE   RecName: Full=Succinate--hydroxymethylglutarate CoA-transferase;
DE            EC=2.8.3.13;
DE   AltName: Full=Dermal papilla-derived protein 13;
DE   AltName: Full=SuccinylCoA:glutarate-CoA transferase;
DE   Flags: Precursor;
GN   Name=SUGCT; Synonyms=C7orf10, DERP13;
DR   GO; GO:0047369; F:succinate-hydroxymethylglutarate CoA-transferase activity; IDA:UniProtKB.
//
ID   SUCO_HUMAN              Reviewed;        1254 AA.
AC   Q9UBS9; B2RNU4; Q9BQB9; Q9BXQ2; Q9UL04;
DE   RecName: Full=SUN domain-containing ossification factor;
DE   AltName: Full=Membrane protein CH1;
DE   AltName: Full=Protein osteopotentia homolog;
DE   AltName: Full=SUN-like protein 1;
DE   Flags: Precursor;
GN   Name=SUCO; Synonyms=C1orf9, CH1, OPT, SLP1;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0046850; P:regulation of bone remodeling; ISS:UniProtKB.
//
ID   SUCR1_HUMAN             Reviewed;         334 AA.
AC   Q9BXA5; A8K305; Q8TDQ8;
DE   RecName: Full=Succinate receptor 1;
DE   AltName: Full=G-protein coupled receptor 91;
DE   AltName: Full=P2Y purinoceptor 1-like;
GN   Name=SUCNR1; Synonyms=GPR91;
DR   GuidetoPHARMACOLOGY; 166; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
//
ID   SUFU_HUMAN              Reviewed;         484 AA.
AC   Q9UMX1; Q7LCP7; Q9NT90; Q9NZ07; Q9UHK2; Q9UHM8; Q9UMY0;
DE   RecName: Full=Suppressor of fused homolog;
DE            Short=SUFUH;
GN   Name=SUFU; ORFNames=UNQ650/PRO1280;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:MGI.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; TAS:BHF-UCL.
DR   GO; GO:2000059; P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.
DR   GO; GO:1901621; P:negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0042992; P:negative regulation of transcription factor import into nucleus; TAS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IEA:Ensembl.
DR   GO; GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IEA:Ensembl.
//
ID   SUGP1_HUMAN             Reviewed;         645 AA.
AC   Q8IWZ8; O60378; Q6P3X9; Q8TCQ4; Q8WWT4; Q8WWT5; Q9NTG3;
DE   RecName: Full=SURP and G-patch domain-containing protein 1;
DE   AltName: Full=RNA-binding protein RBP;
DE   AltName: Full=Splicing factor 4;
GN   Name=SUGP1; Synonyms=SF4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   SUGP2_HUMAN             Reviewed;        1082 AA.
AC   Q8IX01; C9JI71; O15071; O60369; Q5JPH7; Q8WUF7;
DE   RecName: Full=SURP and G-patch domain-containing protein 2;
DE   AltName: Full=Arginine/serine-rich-splicing factor 14;
DE   AltName: Full=Splicing factor, arginine/serine-rich 14;
GN   Name=SUGP2; Synonyms=KIAA0365, SFRS14;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   SUGT1_HUMAN             Reviewed;         365 AA.
AC   Q9Y2Z0; A2A303; Q5JAK5; Q5TAM6; Q6VXY6;
DE   RecName: Full=Suppressor of G2 allele of SKP1 homolog;
DE   AltName: Full=Protein 40-6-3;
DE   AltName: Full=Sgt1;
GN   Name=SUGT1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
//
ID   SUH_HUMAN               Reviewed;         500 AA.
AC   Q06330; B4DY22; Q5XKH9; Q6P1N3;
DE   RecName: Full=Recombining binding protein suppressor of hairless;
DE   AltName: Full=CBF-1;
DE   AltName: Full=J kappa-recombination signal-binding protein;
DE   AltName: Full=RBP-J kappa;
DE            Short=RBP-J;
DE            Short=RBP-JK;
DE   AltName: Full=Renal carcinoma antigen NY-REN-30;
GN   Name=RBPJ; Synonyms=IGKJRB, IGKJRB1, RBPJK, RBPSUH;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000150; F:recombinase activity; NAS:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0060844; P:arterial endothelial cell fate commitment; IEA:Ensembl.
DR   GO; GO:0036302; P:atrioventricular canal development; ISS:BHF-UCL.
DR   GO; GO:0009912; P:auditory receptor cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0097101; P:blood vessel endothelial cell fate specification; ISS:BHF-UCL.
DR   GO; GO:0072554; P:blood vessel lumenization; ISS:BHF-UCL.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060486; P:Clara cell differentiation; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0006310; P:DNA recombination; NAS:UniProtKB.
DR   GO; GO:0035912; P:dorsal aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003160; P:endocardium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0009957; P:epidermal cell fate specification; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:BHF-UCL.
DR   GO; GO:0003198; P:epithelial to mesenchymal transition involved in endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0048820; P:hair follicle maturation; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0002437; P:inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0072602; P:interleukin-4 secretion; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; ISS:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030279; P:negative regulation of ossification; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0061314; P:Notch signaling involved in heart development; IC:BHF-UCL.
DR   GO; GO:0007219; P:Notch signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000138; P:positive regulation of cell proliferation involved in heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:1901189; P:positive regulation of ephrin receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:1901186; P:positive regulation of ERBB signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0007221; P:positive regulation of transcription of Notch receptor target; IDA:UniProtKB.
DR   GO; GO:0048505; P:regulation of timing of cell differentiation; IEA:Ensembl.
DR   GO; GO:0003256; P:regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0048733; P:sebaceous gland development; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0003222; P:ventricular trabecula myocardium morphogenesis; ISS:BHF-UCL.
//
ID   SUIS_HUMAN              Reviewed;        1827 AA.
AC   P14410; A2RUC3; Q1JQ80; Q1RMC2;
DE   RecName: Full=Sucrase-isomaltase, intestinal;
DE   Contains:
DE     RecName: Full=Sucrase;
DE              EC=3.2.1.48;
DE   Contains:
DE     RecName: Full=Isomaltase;
DE              EC=3.2.1.10;
GN   Name=SI;
DR   GO; GO:0004558; F:alpha-glucosidase activity; TAS:Reactome.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004574; F:oligo-1,6-glucosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004575; F:sucrose alpha-glucosidase activity; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044245; P:polysaccharide digestion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SULF1_HUMAN             Reviewed;         871 AA.
AC   Q8IWU6; Q86YV8; Q8NCA2; Q9UPS5;
DE   RecName: Full=Extracellular sulfatase Sulf-1;
DE            Short=hSulf-1;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=SULF1; Synonyms=KIAA1077;
DR   GO; GO:0004065; F:arylsulfatase activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060348; P:bone development; ISS:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; ISS:UniProtKB.
DR   GO; GO:0002063; P:chondrocyte development; ISS:UniProtKB.
DR   GO; GO:0048706; P:embryonic skeletal system development; ISS:UniProtKB.
DR   GO; GO:0014846; P:esophagus smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0035860; P:glial cell-derived neurotrophic factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.
DR   GO; GO:0003094; P:glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0030201; P:heparan sulfate proteoglycan metabolic process; IDA:UniProtKB.
DR   GO; GO:0060384; P:innervation; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060686; P:negative regulation of prostatic bud formation; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IMP:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:UniProtKB.
DR   GO; GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
//
ID   SULF2_HUMAN             Reviewed;         870 AA.
AC   Q8IWU5; E1P5U6; Q5JYE1; Q6UX86; Q96SG2; Q9H1H0; Q9UJR3; Q9ULH3;
DE   RecName: Full=Extracellular sulfatase Sulf-2;
DE            Short=hSulf-2;
DE            EC=3.1.6.-;
DE   Flags: Precursor;
GN   Name=SULF2; Synonyms=KIAA1247; ORFNames=UNQ559/PRO1120;
DR   GO; GO:0004065; F:arylsulfatase activity; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008449; F:N-acetylglucosamine-6-sulfatase activity; IDA:UniProtKB.
DR   GO; GO:0060348; P:bone development; ISS:BHF-UCL.
DR   GO; GO:0051216; P:cartilage development; ISS:UniProtKB.
DR   GO; GO:0002063; P:chondrocyte development; ISS:UniProtKB.
DR   GO; GO:0048706; P:embryonic skeletal system development; ISS:UniProtKB.
DR   GO; GO:0014846; P:esophagus smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0035860; P:glial cell-derived neurotrophic factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.
DR   GO; GO:0003094; P:glomerular filtration; ISS:UniProtKB.
DR   GO; GO:0030201; P:heparan sulfate proteoglycan metabolic process; IDA:UniProtKB.
DR   GO; GO:0060384; P:innervation; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:BHF-UCL.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; ISS:UniProtKB.
//
ID   SUMF1_HUMAN             Reviewed;         374 AA.
AC   Q8NBK3; B4DXK5; B7XD05; E9PGL0; G5E9B0; Q0VAC6; Q0VAC7; Q2NL78;
AC   Q53ZE4; Q6UY39; Q96AK5; Q96DK8;
DE   RecName: Full=Sulfatase-modifying factor 1;
DE            EC=1.8.99.-;
DE   AltName: Full=C-alpha-formylglycine-generating enzyme 1;
DE   Flags: Precursor;
GN   Name=SUMF1; Synonyms=FGE; ORFNames=PSEC0152, UNQ3037/PRO9852;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006687; P:glycosphingolipid metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   SUMF2_HUMAN             Reviewed;         301 AA.
AC   Q8NBJ7; B4DU41; B4DWQ0; Q14DW5; Q53ZE3; Q96BH2; Q9BRN3; Q9BWI1;
AC   Q9Y405;
DE   RecName: Full=Sulfatase-modifying factor 2;
DE   AltName: Full=C-alpha-formylglycine-generating enzyme 2;
DE   Flags: Precursor;
GN   Name=SUMF2; ORFNames=PSEC0171, UNQ1968/PRO4500;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   SUMO1_HUMAN             Reviewed;         101 AA.
AC   P63165; A8MUS8; B2R4I5; P55856; Q6FGG0; Q6NZ62; Q93068;
DE   RecName: Full=Small ubiquitin-related modifier 1;
DE            Short=SUMO-1;
DE   AltName: Full=GAP-modifying protein 1;
DE            Short=GMP1;
DE   AltName: Full=SMT3 homolog 3;
DE   AltName: Full=Sentrin;
DE   AltName: Full=Ubiquitin-homology domain protein PIC1;
DE   AltName: Full=Ubiquitin-like protein SMT3C;
DE            Short=Smt3C;
DE   AltName: Full=Ubiquitin-like protein UBL1;
DE   Flags: Precursor;
GN   Name=SUMO1; Synonyms=SMT3C, SMT3H3, UBL1; ORFNames=OK/SW-cl.43;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IEA:Ensembl.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IMP:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0030578; P:PML body organization; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0090204; P:protein localization to nuclear pore; IEA:Ensembl.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0032880; P:regulation of protein localization; TAS:UniProtKB.
//
ID   SUMO2_HUMAN             Reviewed;          95 AA.
AC   P61956; B2R4I2; P55855; Q32Q42; Q6IPZ6; Q96HK1;
DE   RecName: Full=Small ubiquitin-related modifier 2;
DE            Short=SUMO-2;
DE   AltName: Full=HSMT3;
DE   AltName: Full=SMT3 homolog 2;
DE   AltName: Full=SUMO-3;
DE   AltName: Full=Sentrin-2;
DE   AltName: Full=Ubiquitin-like protein SMT3A;
DE            Short=Smt3A;
DE   Flags: Precursor;
GN   Name=SUMO2; Synonyms=SMT3A, SMT3H2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
//
ID   SUMO3_HUMAN             Reviewed;         103 AA.
AC   P55854; B2R5X4; B4DUW4; Q53HI9; Q6FGD4; Q9BWR4;
DE   RecName: Full=Small ubiquitin-related modifier 3;
DE            Short=SUMO-3;
DE   AltName: Full=SMT3 homolog 1;
DE   AltName: Full=SUMO-2;
DE   AltName: Full=Ubiquitin-like protein SMT3B;
DE            Short=Smt3B;
DE   Flags: Precursor;
GN   Name=SUMO3; Synonyms=SMT3B, SMT3H1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0016925; P:protein sumoylation; IEA:InterPro.
//
ID   SUMO4_HUMAN             Reviewed;          95 AA.
AC   Q6EEV6; A1L3W5;
DE   RecName: Full=Small ubiquitin-related modifier 4;
DE            Short=SUMO-4;
DE   AltName: Full=Small ubiquitin-like protein 4;
DE   Flags: Precursor;
GN   Name=SUMO4; Synonyms=SMT3H4;
DR   GO; GO:0016925; P:protein sumoylation; IEA:InterPro.
//
ID   SUN1_HUMAN              Reviewed;         812 AA.
AC   O94901; A5PL20; B3KMV7; B4DZF7; B7WNY4; B7WP53; E9PDU4; E9PF23;
AC   F8WD13; Q96CZ7; Q9HA14; Q9UH98;
DE   RecName: Full=SUN domain-containing protein 1;
DE   AltName: Full=Protein unc-84 homolog A;
DE   AltName: Full=Sad1/unc-84 protein-like 1;
GN   Name=SUN1; Synonyms=KIAA0810, UNC84A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; IGI:MGI.
DR   GO; GO:0090292; P:nuclear matrix anchoring at nuclear membrane; IDA:UniProtKB.
//
ID   SUN2_HUMAN              Reviewed;         717 AA.
AC   Q9UH99; B0QY62; O75156; Q2NKN8; Q2T9F7; Q504T5; Q6B4H1; Q7Z3E3;
DE   RecName: Full=SUN domain-containing protein 2;
DE   AltName: Full=Protein unc-84 homolog B;
DE   AltName: Full=Rab5-interacting protein;
DE            Short=Rab5IP;
DE   AltName: Full=Sad1/unc-84 protein-like 2;
GN   Name=SUN2; Synonyms=FRIGG, KIAA0668, RAB5IP, UNC84B;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005521; F:lamin binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051642; P:centrosome localization; ISS:UniProtKB.
DR   GO; GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; IGI:MGI.
DR   GO; GO:0090292; P:nuclear matrix anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0007097; P:nuclear migration; TAS:UniProtKB.
DR   GO; GO:0031022; P:nuclear migration along microfilament; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
//
ID   SUN3_HUMAN              Reviewed;         357 AA.
AC   Q8TAQ9; A4D2F3; D3DVM3; Q4F965; Q7Z4U8;
DE   RecName: Full=SUN domain-containing protein 3;
DE   AltName: Full=Sad1/unc-84 domain-containing protein 1;
GN   Name=SUN3; Synonyms=SUNC1;
//
ID   SUN5_HUMAN              Reviewed;         379 AA.
AC   Q8TC36; A6NJ82; Q5T9R0;
DE   RecName: Full=SUN domain-containing protein 5;
DE   AltName: Full=Sad1 and UNC84 domain-containing protein 5;
DE   AltName: Full=Sperm-associated antigen 4-like protein;
DE   AltName: Full=Testis and spermatogenesis-related gene 4 protein;
GN   Name=SUN5; Synonyms=SPAG4L, TSARG4;
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
//
ID   SUOX_HUMAN              Reviewed;         545 AA.
AC   P51687;
DE   RecName: Full=Sulfite oxidase, mitochondrial;
DE            EC=1.8.3.1;
DE   Flags: Precursor;
GN   Name=SUOX;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0008482; F:sulfite oxidase activity; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   SUPT3_HUMAN             Reviewed;         399 AA.
AC   O75486; A6NKG9; B2R9Q5; O76066; Q5TAV9; Q86VN7;
DE   RecName: Full=Transcription initiation protein SPT3 homolog;
DE   AltName: Full=SPT3-like protein;
GN   Name=SUPT3H; Synonyms=SPT3;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   SURF1_HUMAN             Reviewed;         300 AA.
AC   Q15526; Q5T8T3; Q5T8T4;
DE   RecName: Full=Surfeit locus protein 1;
GN   Name=SURF1; Synonyms=SURF-1;
DR   GO; GO:0004129; F:cytochrome-c oxidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0006754; P:ATP biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:1902600; P:hydrogen ion transmembrane transport; TAS:GOC.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:ProtInc.
DR   GO; GO:0006119; P:oxidative phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0008535; P:respiratory chain complex IV assembly; TAS:ProtInc.
//
ID   SURF2_HUMAN             Reviewed;         256 AA.
AC   Q15527; Q6IBP9; Q96CD1;
DE   RecName: Full=Surfeit locus protein 2;
DE            Short=Surf-2;
GN   Name=SURF2;
//
ID   SURF4_HUMAN             Reviewed;         269 AA.
AC   O15260; B7Z6A4; O60923; Q5T8U6; Q9UNZ0; Q9UNZ1;
DE   RecName: Full=Surfeit locus protein 4;
GN   Name=SURF4; Synonyms=SURF-4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0010638; P:positive regulation of organelle organization; IMP:UniProtKB.
//
ID   SURF6_HUMAN             Reviewed;         361 AA.
AC   O75683; Q5T8U1; Q9BRK9; Q9BTZ5; Q9UK24;
DE   RecName: Full=Surfeit locus protein 6;
GN   Name=SURF6; Synonyms=SURF-6;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:Ensembl.
//
ID   SUSD1_HUMAN             Reviewed;         747 AA.
AC   Q6UWL2; A1A4C5; A8KA03; Q5T8V6; Q5T8V7; Q6P9G7; Q8WU83; Q96DM9;
AC   Q9H6V2; Q9NTA7;
DE   RecName: Full=Sushi domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=SUSD1; ORFNames=UNQ2438/PRO4999;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   SUSD2_HUMAN             Reviewed;         822 AA.
AC   Q9UGT4; Q9H5Y6;
DE   RecName: Full=Sushi domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=SUSD2;
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   SUSD3_HUMAN             Reviewed;         255 AA.
AC   Q96L08; Q49AA6; Q6UXV7;
DE   RecName: Full=Sushi domain-containing protein 3;
GN   Name=SUSD3; ORFNames=UNQ9387/PRO34275;
//
ID   SUSD4_HUMAN             Reviewed;         490 AA.
AC   Q5VX71; D3DTB9; Q6UX62; Q9BSR0; Q9NWG0;
DE   RecName: Full=Sushi domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=SUSD4; ORFNames=UNQ196/PRO222;
//
ID   SUSD5_HUMAN             Reviewed;         629 AA.
AC   O60279;
DE   RecName: Full=Sushi domain-containing protein 5;
DE   Flags: Precursor;
GN   Name=SUSD5; Synonyms=KIAA0527;
DR   GO; GO:0005540; F:hyaluronic acid binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
//
ID   SUV3_HUMAN              Reviewed;         786 AA.
AC   Q8IYB8; A8K301; O43630;
DE   RecName: Full=ATP-dependent RNA helicase SUPV3L1, mitochondrial;
DE            EC=3.6.4.13;
DE   AltName: Full=Suppressor of var1 3-like protein 1;
DE            Short=SUV3-like protein 1;
DE   Flags: Precursor;
GN   Name=SUPV3L1; Synonyms=SUV3;
DR   GO; GO:0034458; F:3'-5' RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IMP:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; IMP:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0070827; P:chromatin maintenance; IMP:UniProtKB.
DR   GO; GO:0032508; P:DNA duplex unwinding; IMP:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IMP:UniProtKB.
DR   GO; GO:0000958; P:mitochondrial mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0035946; P:mitochondrial mRNA surveillance; IMP:UniProtKB.
DR   GO; GO:0035945; P:mitochondrial ncRNA surveillance; IMP:UniProtKB.
DR   GO; GO:0000965; P:mitochondrial RNA 3'-end processing; IMP:UniProtKB.
DR   GO; GO:2000827; P:mitochondrial RNA surveillance; IMP:UniProtKB.
DR   GO; GO:0070584; P:mitochondrion morphogenesis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0000962; P:positive regulation of mitochondrial RNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0006401; P:RNA catabolic process; IMP:UniProtKB.
//
ID   SUV91_HUMAN             Reviewed;         412 AA.
AC   O43463; B2R6E8; B4DST0; Q53G60; Q6FHK6;
DE   RecName: Full=Histone-lysine N-methyltransferase SUV39H1;
DE            EC=2.1.1.43;
DE   AltName: Full=Histone H3-K9 methyltransferase 1;
DE            Short=H3-K9-HMTase 1;
DE   AltName: Full=Lysine N-methyltransferase 1A;
DE   AltName: Full=Position-effect variegation 3-9 homolog;
DE   AltName: Full=Suppressor of variegation 3-9 homolog 1;
DE            Short=Su(var)3-9 homolog 1;
GN   Name=SUV39H1; Synonyms=KMT1A, SUV39H;
DR   GO; GO:0003682; F:chromatin binding; TAS:ProtInc.
DR   GO; GO:0042054; F:histone methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:ProtInc.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SUV92_HUMAN             Reviewed;         410 AA.
AC   Q9H5I1; D3DRT4; Q5JSS4; Q5JSS5; Q6I9Y3; Q8ND06;
DE   RecName: Full=Histone-lysine N-methyltransferase SUV39H2;
DE            EC=2.1.1.43;
DE   AltName: Full=Histone H3-K9 methyltransferase 2;
DE            Short=H3-K9-HMTase 2;
DE   AltName: Full=Lysine N-methyltransferase 1B;
DE   AltName: Full=Suppressor of variegation 3-9 homolog 2;
DE            Short=Su(var)3-9 homolog 2;
GN   Name=SUV39H2; Synonyms=KMT1B;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006333; P:chromatin assembly or disassembly; IMP:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IDA:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SUZ12_HUMAN             Reviewed;         739 AA.
AC   Q15022; Q96BD9;
DE   RecName: Full=Polycomb protein SUZ12;
DE   AltName: Full=Chromatin precipitated E2F target 9 protein;
DE            Short=ChET 9 protein;
DE   AltName: Full=Joined to JAZF1 protein;
DE   AltName: Full=Suppressor of zeste 12 protein homolog;
GN   Name=SUZ12; Synonyms=CHET9, JJAZ1, KIAA0160;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0042054; F:histone methyltransferase activity; IMP:MGI.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0016574; P:histone ubiquitination; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SV2A_HUMAN              Reviewed;         742 AA.
AC   Q7L0J3; D3DUZ7; O94841; Q5QNX8; Q7Z3L6; Q8NBJ6; Q9BVZ9;
DE   RecName: Full=Synaptic vesicle glycoprotein 2A;
GN   Name=SV2A; Synonyms=KIAA0736; ORFNames=PSEC0174;
DR   GO; GO:0004872; F:receptor activity; IEA:Ensembl.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
//
ID   SV2B_HUMAN              Reviewed;         683 AA.
AC   Q7L1I2; B4DH30; C6G489; O94840; Q6IAR8;
DE   RecName: Full=Synaptic vesicle glycoprotein 2B;
GN   Name=SV2B; Synonyms=KIAA0735;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
//
ID   SV2C_HUMAN              Reviewed;         727 AA.
AC   Q496J9; Q496K1; Q9UPU8;
DE   RecName: Full=Synaptic vesicle glycoprotein 2C;
GN   Name=SV2C; Synonyms=KIAA1054;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
//
ID   SV421_HUMAN             Reviewed;         885 AA.
AC   Q4FZB7; B7WNX7; Q3SX56; Q4V775; Q6P150; Q96E44; Q9BUL0; Q9H022;
AC   Q9H2K3; Q9NXV3; Q9Y393;
DE   RecName: Full=Histone-lysine N-methyltransferase SUV420H1;
DE            EC=2.1.1.43;
DE   AltName: Full=Lysine N-methyltransferase 5B;
DE   AltName: Full=Suppressor of variegation 4-20 homolog 1;
DE            Short=Su(var)4-20 homolog 1;
DE            Short=Suv4-20h1;
GN   Name=SUV420H1; Synonyms=KMT5B; ORFNames=CGI-85;
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IEA:Ensembl.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0034773; P:histone H4-K20 trimethylation; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SV422_HUMAN             Reviewed;         462 AA.
AC   Q86Y97; Q8WZ10; Q9BRZ6;
DE   RecName: Full=Histone-lysine N-methyltransferase SUV420H2;
DE            EC=2.1.1.43;
DE   AltName: Full=Lysine N-methyltransferase 5C;
DE   AltName: Full=Suppressor of variegation 4-20 homolog 2;
DE            Short=Su(var)4-20 homolog 2;
DE            Short=Suv4-20h2;
GN   Name=SUV420H2; Synonyms=KMT5C; ORFNames=PP7130;
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034773; P:histone H4-K20 trimethylation; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   SVEP1_HUMAN             Reviewed;        3571 AA.
AC   Q4LDE5; Q0P675; Q5D213; Q5T938; Q5VTE4; Q5VTE5; Q7Z387; Q7Z3G3;
AC   Q8NBT9; Q96JU7; Q9H284; Q9H8J9;
DE   RecName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1;
DE   AltName: Full=CCP module-containing protein 22;
DE   AltName: Full=Polydom;
DE   AltName: Full=Selectin-like osteoblast-derived protein;
DE            Short=SEL-OB;
DE   AltName: Full=Serologically defined breast cancer antigen NY-BR-38;
DE   Flags: Precursor;
GN   Name=SVEP1; Synonyms=C9orf13, CCP22, SELOB;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   SVIL_HUMAN              Reviewed;        2214 AA.
AC   O95425; D3DRW9; M1J557; O60611; O60612; Q5VZK5; Q5VZK6; Q9H1R7;
DE   RecName: Full=Supervillin;
DE   AltName: Full=Archvillin;
DE   AltName: Full=p205/p250;
GN   Name=SVIL;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IMP:UniProtKB.
//
ID   SVIP_HUMAN              Reviewed;          77 AA.
AC   Q8NHG7;
DE   RecName: Full=Small VCP/p97-interacting protein;
GN   Name=SVIP;
//
ID   SVOPL_HUMAN             Reviewed;         492 AA.
AC   Q8N434;
DE   RecName: Full=Putative transporter SVOPL;
DE   AltName: Full=SV2-related protein-like;
DE   AltName: Full=SVOP-like protein;
GN   Name=SVOPL;
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
//
ID   SVOP_HUMAN              Reviewed;         548 AA.
AC   Q8N4V2; Q9NPW5;
DE   RecName: Full=Synaptic vesicle 2-related protein;
DE            Short=SV2-related protein;
GN   Name=SVOP;
DR   GO; GO:0015075; F:ion transmembrane transporter activity; IEA:InterPro.
//
ID   SWAHA_HUMAN             Reviewed;         549 AA.
AC   Q2M3V2; Q8NAE7;
DE   RecName: Full=Ankyrin repeat domain-containing protein SOWAHA;
DE   AltName: Full=Ankyrin repeat domain-containing protein 43;
DE   AltName: Full=Protein sosondowah homolog A;
DE   Flags: Precursor;
GN   Name=SOWAHA; Synonyms=ANKRD43;
//
ID   SWAHB_HUMAN             Reviewed;         793 AA.
AC   A6NEL2; B2RP29;
DE   RecName: Full=Ankyrin repeat domain-containing protein SOWAHB;
DE   AltName: Full=Ankyrin repeat domain-containing protein 56;
DE   AltName: Full=Protein sosondowah homolog B;
GN   Name=SOWAHB; Synonyms=ANKRD56;
//
ID   SWAHC_HUMAN             Reviewed;         525 AA.
AC   Q53LP3; Q8NE15; Q9H6U1;
DE   RecName: Full=Ankyrin repeat domain-containing protein SOWAHC;
DE   AltName: Full=Ankyrin repeat domain-containing protein 57;
DE   AltName: Full=Protein sosondowah homolog C;
GN   Name=SOWAHC; Synonyms=ANKRD57, C2orf26;
//
ID   SWAHD_HUMAN             Reviewed;         315 AA.
AC   A6NJG2;
DE   RecName: Full=Ankyrin repeat domain-containing protein SOWAHD;
DE   AltName: Full=Ankyrin repeat domain-containing protein 58;
DE   AltName: Full=Protein sosondowah homolog D;
GN   Name=SOWAHD; Synonyms=ANKRD58;
//
ID   SWAP1_HUMAN             Reviewed;         229 AA.
AC   Q6NVH7; Q8NAM1;
DE   RecName: Full=ATPase SWSAP1;
DE   AltName: Full=SWIM-type zinc finger 7-associated protein 1;
DE   AltName: Full=SWS1-associated protein 1;
DE   AltName: Full=ZSWIM7-associated protein 1;
DE            Short=ZSWIM7AP1;
GN   Name=SWSAP1; Synonyms=C19orf39;
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
//
ID   SWET1_HUMAN             Reviewed;         221 AA.
AC   Q9BRV3; Q5SR64; Q6IAK6; Q96DC5; Q9UHQ2; Q9UHQ3;
DE   RecName: Full=Sugar transporter SWEET1;
DE            Short=HsSWEET1;
DE   AltName: Full=RAG1-activating protein 1;
DE   AltName: Full=Solute carrier family 50 member 1;
DE   AltName: Full=Stromal cell protein;
GN   Name=SLC50A1; Synonyms=RAG1AP1, SCP;
DR   GO; GO:0042947; F:glucoside transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0042946; P:glucoside transport; IDA:GOC.
DR   GO; GO:0045815; P:positive regulation of gene expression, epigenetic; ISS:HGNC.
//
ID   SWI5_HUMAN              Reviewed;         235 AA.
AC   Q1ZZU3; Q5SYX7; Q5SYX8; Q8N2W6;
DE   RecName: Full=DNA repair protein SWI5 homolog;
DE   AltName: Full=HBV DNAPTP1-transactivated protein A;
DE   AltName: Full=Protein SAE3 homolog;
GN   Name=SWI5; Synonyms=C9orf119, SAE3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071479; P:cellular response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
//
ID   SWP70_HUMAN             Reviewed;         585 AA.
AC   Q9UH65; D3DQV1; O75135; Q7LCY6; Q9P061; Q9P0Z8;
DE   RecName: Full=Switch-associated protein 70;
DE            Short=SWAP-70;
GN   Name=SWAP70; Synonyms=KIAA0640; ORFNames=HSPC321;
DR   GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
//
ID   SWT1_HUMAN              Reviewed;         900 AA.
AC   Q5T5J6; Q8NEK9; Q9BZQ7; Q9NXQ0;
DE   RecName: Full=Transcriptional protein SWT1;
GN   Name=SWT1; Synonyms=C1orf26;
//
ID   SY14L_HUMAN             Reviewed;         188 AA.
AC   Q58G82; A2RTZ8; Q9BQR7;
DE   RecName: Full=Putative synaptotagmin-14-like protein;
DE   AltName: Full=Synaptotagmin XIV-derived protein;
DE   AltName: Full=Synaptotagmin XIV-like protein;
GN   Name=SYT14L; Synonyms=SYTDEP;
//
ID   SYAC_HUMAN              Reviewed;         968 AA.
AC   P49588; A6NF14; Q53GV7; Q96FA0;
DE   RecName: Full=Alanine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.7;
DE   AltName: Full=Alanyl-tRNA synthetase;
DE            Short=AlaRS;
DE   AltName: Full=Renal carcinoma antigen NY-REN-42;
GN   Name=AARS;
DR   GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; TAS:ProtInc.
DR   GO; GO:0006419; P:alanyl-tRNA aminoacylation; TAS:ProtInc.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0021680; P:cerebellar Purkinje cell layer development; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0006400; P:tRNA modification; IEA:Ensembl.
DR   GO; GO:0008033; P:tRNA processing; TAS:ProtInc.
//
ID   SYAP1_HUMAN             Reviewed;         352 AA.
AC   Q96A49; Q68CP1; Q96C60; Q96JQ6; Q96T20;
DE   RecName: Full=Synapse-associated protein 1;
GN   Name=SYAP1; ORFNames=PRO3113;
//
ID   SYAM_HUMAN              Reviewed;         985 AA.
AC   Q5JTZ9; A2RRN5; Q8N198; Q96D02; Q9ULF0;
DE   RecName: Full=Alanine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.7;
DE   AltName: Full=Alanyl-tRNA synthetase;
DE            Short=AlaRS;
DE   Flags: Precursor;
GN   Name=AARS2; Synonyms=AARSL, KIAA1270;
DR   GO; GO:0004813; F:alanine-tRNA ligase activity; IMP:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0070143; P:mitochondrial alanyl-tRNA aminoacylation; IMP:BHF-UCL.
DR   GO; GO:0033108; P:mitochondrial respiratory chain complex assembly; IMP:BHF-UCL.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYBU_HUMAN              Reviewed;         663 AA.
AC   Q9NX95; A8K354; B3KQX3; B3KU61; Q5R1T1; Q5R1T2; Q5R1T3; Q5Y2M6;
AC   Q8ND49; Q8TCR6; Q96D80; Q9P256;
DE   RecName: Full=Syntabulin;
DE   AltName: Full=Golgi-localized syntaphilin-related protein;
DE   AltName: Full=Syntaxin-1-binding protein;
GN   Name=SYBU; Synonyms=GOLSYN, KIAA1472;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
//
ID   SYC1L_HUMAN             Reviewed;         242 AA.
AC   A8MT33; A6NF23;
DE   RecName: Full=Synaptonemal complex central element protein 1-like;
DE   AltName: Full=Meiosis-related protein;
GN   Name=SYCE1L;
DR   GO; GO:0007130; P:synaptonemal complex assembly; IEA:InterPro.
//
ID   SYC2L_HUMAN             Reviewed;         812 AA.
AC   Q5T4T6; A6NDS5; Q08GK5; Q6ZRM2; Q96EJ2;
DE   RecName: Full=Synaptonemal complex protein 2-like;
DE            Short=SCP-2-like;
DE   AltName: Full=145 kDa nucleolar protein homolog;
DE            Short=hsNO145;
GN   Name=SYCP2L; Synonyms=C6orf177, NO145;
//
ID   SYCC_HUMAN              Reviewed;         748 AA.
AC   P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25;
DE   RecName: Full=Cysteine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.16;
DE   AltName: Full=Cysteinyl-tRNA synthetase;
DE            Short=CysRS;
GN   Name=CARS;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004817; F:cysteine-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0006423; P:cysteinyl-tRNA aminoacylation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYCE1_HUMAN             Reviewed;         351 AA.
AC   Q8N0S2; B2RC80; Q9BWU3; Q9BWU4;
DE   RecName: Full=Synaptonemal complex central element protein 1;
DE   AltName: Full=Cancer/testis antigen 76;
DE            Short=CT76;
GN   Name=SYCE1; Synonyms=C10orf94;
DR   GO; GO:0007130; P:synaptonemal complex assembly; IC:BHF-UCL.
//
ID   SYCE2_HUMAN             Reviewed;         218 AA.
AC   Q6PIF2; B4DYD3;
DE   RecName: Full=Synaptonemal complex central element protein 2;
DE   AltName: Full=Central element synaptonemal complex protein 1;
GN   Name=SYCE2; Synonyms=CESC1;
DR   GO; GO:0007130; P:synaptonemal complex assembly; IC:BHF-UCL.
//
ID   SYCE3_HUMAN             Reviewed;          88 AA.
AC   A1L190;
DE   RecName: Full=Synaptonemal complex central element protein 3;
DE   AltName: Full=Testis highly expressed gene 2 protein;
DE            Short=THEG-2;
GN   Name=SYCE3; Synonyms=C22orf41, THEG2;
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.
//
ID   SYCM_HUMAN              Reviewed;         564 AA.
AC   Q9HA77; Q8NI84; Q96IV4;
DE   RecName: Full=Probable cysteine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.16;
DE   AltName: Full=Cysteinyl-tRNA synthetase;
DE            Short=CysRS;
DE   Flags: Precursor;
GN   Name=CARS2; ORFNames=OK/SW-cl.10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004817; F:cysteine-tRNA ligase activity; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006423; P:cysteinyl-tRNA aminoacylation; IBA:RefGenome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYCN_HUMAN              Reviewed;         134 AA.
AC   Q0VAF6;
DE   RecName: Full=Syncollin;
DE   AltName: Full=Insulin synthesis-associated protein 1;
DE   Flags: Precursor;
GN   Name=SYCN; Synonyms=INSSA1, SYL;
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
//
ID   SYCP1_HUMAN             Reviewed;         976 AA.
AC   Q15431; O14963; Q5VXJ6;
DE   RecName: Full=Synaptonemal complex protein 1;
DE            Short=SCP-1;
DE   AltName: Full=Cancer/testis antigen 8;
DE            Short=CT8;
GN   Name=SYCP1; Synonyms=SCP1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0007130; P:synaptonemal complex assembly; ISS:HGNC.
//
ID   SYCP2_HUMAN             Reviewed;        1530 AA.
AC   Q9BX26; A2RUE5; O75763; Q5JX11; Q9NTX8; Q9UG27;
DE   RecName: Full=Synaptonemal complex protein 2;
DE            Short=SCP-2;
DE   AltName: Full=Synaptonemal complex lateral element protein;
DE            Short=hsSCP2;
GN   Name=SYCP2; Synonyms=SCP2;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0007143; P:female meiotic division; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0048808; P:male genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0007128; P:meiotic prophase I; NAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007130; P:synaptonemal complex assembly; NAS:UniProtKB.
//
ID   SYCP3_HUMAN             Reviewed;         236 AA.
AC   Q8IZU3;
DE   RecName: Full=Synaptonemal complex protein 3;
DE            Short=SCP-3;
GN   Name=SYCP3; Synonyms=SCP3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007141; P:male meiosis I; NAS:UniProtKB.
DR   GO; GO:0035093; P:spermatogenesis, exchange of chromosomal proteins; IMP:UniProtKB.
//
ID   SYDC_HUMAN              Reviewed;         501 AA.
AC   P14868; A8K3J2; D3DP77; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q9BW52;
DE   RecName: Full=Aspartate--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.12;
DE   AltName: Full=Aspartyl-tRNA synthetase;
DE            Short=AspRS;
DE   AltName: Full=Cell proliferation-inducing gene 40 protein;
GN   Name=DARS; ORFNames=PIG40;
DR   GO; GO:0004046; F:aminoacylase activity; TAS:ProtInc.
DR   GO; GO:0004815; F:aspartate-tRNA ligase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006422; P:aspartyl-tRNA aminoacylation; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYDE2_HUMAN             Reviewed;        1194 AA.
AC   Q5VT97; Q5VT96; Q8NDB8; Q9H8A6;
DE   RecName: Full=Rho GTPase-activating protein SYDE2;
DE   AltName: Full=Synapse defective protein 1 homolog 2;
DE            Short=Protein syd-1 homolog 2;
GN   Name=SYDE2;
DR   GO; GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   SYDE1_HUMAN             Reviewed;         735 AA.
AC   Q6ZW31; Q7L2I8; Q8N6J2; Q9H8K4;
DE   RecName: Full=Rho GTPase-activating protein SYDE1;
DE   AltName: Full=Synapse defective protein 1 homolog 1;
DE            Short=Protein syd-1 homolog 1;
GN   Name=SYDE1;
DR   GO; GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   SYDM_HUMAN              Reviewed;         645 AA.
AC   Q6PI48;
DE   RecName: Full=Aspartate--tRNA ligase, mitochondrial;
DE            EC=6.1.1.12;
DE   AltName: Full=Aspartyl-tRNA synthetase;
DE            Short=AspRS;
DE   Flags: Precursor;
GN   Name=DARS2;
DR   GO; GO:0004815; F:aspartate-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0050560; F:aspartate-tRNA(Asn) ligase activity; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0000049; F:tRNA binding; TAS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0070145; P:mitochondrial asparaginyl-tRNA aminoacylation; IC:BHF-UCL.
DR   GO; GO:0043039; P:tRNA aminoacylation; IDA:BHF-UCL.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYEM_HUMAN              Reviewed;         523 AA.
AC   Q5JPH6; B3KTT2; D3DWF1; Q8TF31;
DE   RecName: Full=Probable glutamate--tRNA ligase, mitochondrial;
DE            EC=6.1.1.17;
DE   AltName: Full=Glutamyl-tRNA synthetase;
DE            Short=GluRS;
DE   Flags: Precursor;
GN   Name=EARS2; Synonyms=KIAA1970;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004818; F:glutamate-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0050561; F:glutamate-tRNA(Gln) ligase activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006424; P:glutamyl-tRNA aminoacylation; IDA:UniProtKB.
DR   GO; GO:0070127; P:tRNA aminoacylation for mitochondrial protein translation; IDA:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYEP_HUMAN              Reviewed;        1512 AA.
AC   P07814; A0AVA9; B9EGH3; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57;
AC   Q86X73;
DE   RecName: Full=Bifunctional glutamate/proline--tRNA ligase;
DE   AltName: Full=Bifunctional aminoacyl-tRNA synthetase;
DE   AltName: Full=Cell proliferation-inducing gene 32 protein;
DE   AltName: Full=Glutamatyl-prolyl-tRNA synthetase;
DE   Includes:
DE     RecName: Full=Glutamate--tRNA ligase;
DE              EC=6.1.1.17;
DE     AltName: Full=Glutamyl-tRNA synthetase;
DE              Short=GluRS;
DE   Includes:
DE     RecName: Full=Proline--tRNA ligase;
DE              EC=6.1.1.15;
DE     AltName: Full=Prolyl-tRNA synthetase;
GN   Name=EPRS; Synonyms=GLNS, PARS, QARS, QPRS; ORFNames=PIG32;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004818; F:glutamate-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0004827; F:proline-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035613; F:RNA stem-loop binding; IDA:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006424; P:glutamyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYF1_HUMAN              Reviewed;         855 AA.
AC   Q9HCS7; Q8TET6; Q96HB0; Q96IW0; Q9NRG6; Q9ULP3;
DE   RecName: Full=Pre-mRNA-splicing factor SYF1;
DE   AltName: Full=Protein HCNP;
DE   AltName: Full=XPA-binding protein 2;
GN   Name=XAB2; Synonyms=HCNP, KIAA1177, SYF1; ORFNames=PP3898;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IDA:UniProtKB.
//
ID   SYF2_HUMAN              Reviewed;         243 AA.
AC   O95926; Q5TH73;
DE   RecName: Full=Pre-mRNA-splicing factor SYF2;
DE   AltName: Full=CCNDBP1-interactor;
DE   AltName: Full=p29;
GN   Name=SYF2; Synonyms=CBPIN, GCIPIP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0048568; P:embryonic organ development; IEA:Ensembl.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   SYFA_HUMAN              Reviewed;         508 AA.
AC   Q9Y285; Q9NSD8; Q9Y4W8;
DE   RecName: Full=Phenylalanine--tRNA ligase alpha subunit;
DE            EC=6.1.1.20;
DE   AltName: Full=CML33;
DE   AltName: Full=Phenylalanyl-tRNA synthetase alpha subunit;
DE            Short=PheRS;
GN   Name=FARSA; Synonyms=FARS, FARSL, FARSLA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004826; F:phenylalanine-tRNA ligase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYFB_HUMAN              Reviewed;         589 AA.
AC   Q9NSD9; O95708; Q4ZFX1; Q57ZJ5; Q9NZZ6;
DE   RecName: Full=Phenylalanine--tRNA ligase beta subunit;
DE            EC=6.1.1.20;
DE   AltName: Full=Phenylalanyl-tRNA synthetase beta subunit;
DE            Short=PheRS;
GN   Name=FARSB; Synonyms=FARSLB, FRSB; ORFNames=HSPC173;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004826; F:phenylalanine-tRNA ligase activity; TAS:ProtInc.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYFM_HUMAN              Reviewed;         451 AA.
AC   O95363; B2R664; Q53F66; Q5TCS3; Q6FG29; Q9NPY7; Q9P062;
DE   RecName: Full=Phenylalanine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.20;
DE   AltName: Full=Phenylalanyl-tRNA synthetase;
DE            Short=PheRS;
DE   Flags: Precursor;
GN   Name=FARS2; Synonyms=FARS1; ORFNames=HSPC320;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006432; P:phenylalanyl-tRNA aminoacylation; IDA:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0008033; P:tRNA processing; IDA:UniProtKB.
//
ID   SYGP1_HUMAN             Reviewed;        1343 AA.
AC   Q96PV0; A2AB17; A2BEL6; A2BEL7; A8MQC4; Q8TCS2; Q9UGE2;
DE   RecName: Full=Ras/Rap GTPase-activating protein SynGAP;
DE   AltName: Full=Neuronal RasGAP;
DE   AltName: Full=Synaptic Ras GTPase-activating protein 1;
DE            Short=Synaptic Ras-GAP 1;
GN   Name=SYNGAP1; Synonyms=KIAA1938;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IBA:RefGenome.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0043113; P:receptor clustering; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0050803; P:regulation of synapse structure and activity; IEA:Ensembl.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   SYG_HUMAN               Reviewed;         739 AA.
AC   P41250; B3KQA2; B4DIA0; Q969Y1;
DE   RecName: Full=Glycine--tRNA ligase;
DE            EC=6.1.1.14;
DE   AltName: Full=Diadenosine tetraphosphate synthetase;
DE            Short=AP-4-A synthetase;
DE   AltName: Full=Glycyl-tRNA synthetase;
DE            Short=GlyRS;
GN   Name=GARS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0015966; P:diadenosine tetraphosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYHC_HUMAN              Reviewed;         509 AA.
AC   P12081; B4DHQ1; B4DY73; D6REN6; J3KNE5;
DE   RecName: Full=Histidine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.21;
DE   AltName: Full=Histidyl-tRNA synthetase;
DE            Short=HisRS;
GN   Name=HARS; Synonyms=HRS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004821; F:histidine-tRNA ligase activity; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYHM_HUMAN              Reviewed;         506 AA.
AC   P49590;
DE   RecName: Full=Probable histidine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.21;
DE   AltName: Full=Histidine--tRNA ligase-like;
DE   AltName: Full=Histidyl-tRNA synthetase;
DE            Short=HisRS;
DE   Flags: Precursor;
GN   Name=HARS2; Synonyms=HARSL, HARSR, HO3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004821; F:histidine-tRNA ligase activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYIC_HUMAN              Reviewed;        1262 AA.
AC   P41252; A8KAE9; Q5TCD0; Q7Z3T4; Q9H588;
DE   RecName: Full=Isoleucine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.5;
DE   AltName: Full=Isoleucyl-tRNA synthetase;
DE            Short=IRS;
DE            Short=IleRS;
GN   Name=IARS;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004822; F:isoleucine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006428; P:isoleucyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYIM_HUMAN              Reviewed;        1012 AA.
AC   Q9NSE4; B2RPG8; Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8;
AC   Q9NW42;
DE   RecName: Full=Isoleucine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.5;
DE   AltName: Full=Isoleucyl-tRNA synthetase;
DE            Short=IleRS;
DE   Flags: Precursor;
GN   Name=IARS2;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004822; F:isoleucine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006428; P:isoleucyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYJ2B_HUMAN             Reviewed;         145 AA.
AC   P57105; Q49SH3; Q96IA4;
DE   RecName: Full=Synaptojanin-2-binding protein;
DE   AltName: Full=Mitochondrial outer membrane protein 25;
GN   Name=SYNJ2BP; Synonyms=OMP25;
DR   GO; GO:0048312; P:intracellular distribution of mitochondria; IEA:Ensembl.
DR   GO; GO:0032926; P:negative regulation of activin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0032927; P:positive regulation of activin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:2000010; P:positive regulation of protein localization to cell surface; IEA:Ensembl.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IEA:Ensembl.
//
ID   SYK_HUMAN               Reviewed;         597 AA.
AC   Q15046; A8MSK1; D3DUK4; O14946; Q96J25; Q9HB23;
DE   RecName: Full=Lysine--tRNA ligase;
DE            EC=6.1.1.6;
DE   AltName: Full=Lysyl-tRNA synthetase;
DE            Short=LysRS;
GN   Name=KARS; Synonyms=KIAA0070;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004824; F:lysine-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000049; F:tRNA binding; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0015966; P:diadenosine tetraphosphate biosynthetic process; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006430; P:lysyl-tRNA aminoacylation; IDA:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0008033; P:tRNA processing; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   SYLC_HUMAN              Reviewed;        1176 AA.
AC   Q9P2J5; A7E266; Q9NSE1;
DE   RecName: Full=Leucine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.4;
DE   AltName: Full=Leucyl-tRNA synthetase;
DE            Short=LeuRS;
GN   Name=LARS; Synonyms=KIAA1352;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004823; F:leucine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006429; P:leucyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYLM_HUMAN              Reviewed;         903 AA.
AC   Q15031;
DE   RecName: Full=Probable leucine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.4;
DE   AltName: Full=Leucyl-tRNA synthetase;
DE            Short=LeuRS;
DE   Flags: Precursor;
GN   Name=LARS2; Synonyms=KIAA0028;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004823; F:leucine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006429; P:leucyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYMC_HUMAN              Reviewed;         900 AA.
AC   P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0;
DE   RecName: Full=Methionine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.10;
DE   AltName: Full=Methionyl-tRNA synthetase;
DE            Short=MetRS;
GN   Name=MARS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004825; F:methionine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYMM_HUMAN              Reviewed;         593 AA.
AC   Q96GW9; A0AVC3; Q76E79; Q8IW62; Q8N7N4;
DE   RecName: Full=Methionine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.10;
DE   AltName: Full=Methionyl-tRNA synthetase 2;
DE   AltName: Full=Mitochondrial methionyl-tRNA synthetase;
DE            Short=MtMetRS;
DE   Flags: Precursor;
GN   Name=MARS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004825; F:methionine-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006431; P:methionyl-tRNA aminoacylation; IDA:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYMPK_HUMAN             Reviewed;        1274 AA.
AC   Q92797; O00521; O00689; O00733; Q59GT5; Q8N2U5;
DE   RecName: Full=Symplekin;
GN   Name=SYMPK; Synonyms=SPK;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:UniProtKB.
//
ID   SYN1L_HUMAN             Reviewed;         238 AA.
AC   A6NDD5;
DE   RecName: Full=Synapse differentiation-inducing gene protein 1-like;
DE   AltName: Full=Capucin;
DE   AltName: Full=Dispanin subfamily C member 1;
DE            Short=DSPC1;
DE   AltName: Full=Transmembrane protein 90A;
GN   Name=SYNDIG1L; Synonyms=TMEM90A;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   SYN1_HUMAN              Reviewed;         705 AA.
AC   P17600; B1AJQ1; O75825; Q5H9A9;
DE   RecName: Full=Synapsin-1;
DE   AltName: Full=Brain protein 4.1;
DE   AltName: Full=Synapsin I;
GN   Name=SYN1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   SYN2_HUMAN              Reviewed;         582 AA.
AC   Q92777; A8MY98;
DE   RecName: Full=Synapsin-2;
DE   AltName: Full=Synapsin II;
GN   Name=SYN2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   SYN3_HUMAN              Reviewed;         580 AA.
AC   O14994; B1B1F9;
DE   RecName: Full=Synapsin-3;
DE   AltName: Full=Synapsin III;
GN   Name=SYN3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:ProtInc.
//
ID   SYNCI_HUMAN             Reviewed;         482 AA.
AC   Q9H7C4; B4DNK8; B4DY58; C9IY41;
DE   RecName: Full=Syncoilin;
DE   AltName: Full=Syncoilin intermediate filament 1;
DE   AltName: Full=Syncoilin-1;
GN   Name=SYNC; Synonyms=SYNC1;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0045103; P:intermediate filament-based process; IEA:Ensembl.
//
ID   SYNC_HUMAN              Reviewed;         548 AA.
AC   O43776; Q53GU6;
DE   RecName: Full=Asparagine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.22;
DE   AltName: Full=Asparaginyl-tRNA synthetase;
DE            Short=AsnRS;
GN   Name=NARS;
DR   GO; GO:0004816; F:asparagine-tRNA ligase activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006421; P:asparaginyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYNE1_HUMAN             Reviewed;        8797 AA.
AC   Q8NF91; E7EQI5; O94890; Q5JV19; Q5JV22; Q8N9P7; Q8TCP1; Q8WWW6;
AC   Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50;
AC   Q9UJ06; Q9UJ07; Q9ULF8;
DE   RecName: Full=Nesprin-1;
DE   AltName: Full=Enaptin;
DE   AltName: Full=Myocyte nuclear envelope protein 1;
DE            Short=Myne-1;
DE   AltName: Full=Nuclear envelope spectrin repeat protein 1;
DE   AltName: Full=Synaptic nuclear envelope protein 1;
DE            Short=Syne-1;
GN   Name=SYNE1; Synonyms=C6orf98, KIAA0796, KIAA1262, KIAA1756, MYNE1;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0051015; F:actin filament binding; ISS:UniProtKB.
DR   GO; GO:0005521; F:lamin binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IDA:UniProtKB.
DR   GO; GO:0042692; P:muscle cell differentiation; IDA:UniProtKB.
DR   GO; GO:0090292; P:nuclear matrix anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0006997; P:nucleus organization; NAS:UniProtKB.
//
ID   SYNE2_HUMAN             Reviewed;        6885 AA.
AC   Q8WXH0; Q540G1; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5;
AC   Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1;
DE   RecName: Full=Nesprin-2;
DE   AltName: Full=Nuclear envelope spectrin repeat protein 2;
DE   AltName: Full=Nucleus and actin connecting element protein;
DE            Short=Protein NUANCE;
DE   AltName: Full=Synaptic nuclear envelope protein 2;
DE            Short=Syne-2;
GN   Name=SYNE2; Synonyms=KIAA1011, NUA;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051642; P:centrosome localization; IMP:UniProtKB.
DR   GO; GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:Ensembl.
DR   GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
DR   GO; GO:0006998; P:nuclear envelope organization; IEA:Ensembl.
DR   GO; GO:0007097; P:nuclear migration; IMP:UniProtKB.
DR   GO; GO:0031022; P:nuclear migration along microfilament; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
//
ID   SYNE3_HUMAN             Reviewed;         975 AA.
AC   Q6ZMZ3; A6H8H3; Q86SX5; Q8N7G8;
DE   RecName: Full=Nesprin-3;
DE   AltName: Full=Nuclear envelope spectrin repeat protein 3;
GN   Name=SYNE3; Synonyms=C14orf49;
DR   GO; GO:0051015; F:actin filament binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0090150; P:establishment of protein localization to membrane; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   SYNE4_HUMAN             Reviewed;         404 AA.
AC   Q8N205; A8MRS0; A8MYE3; Q7Z7L3;
DE   RecName: Full=Nesprin-4;
DE   AltName: Full=Nuclear envelope spectrin repeat protein 4;
GN   Name=SYNE4; Synonyms=C19orf46;
DR   GO; GO:0045198; P:establishment of epithelial cell apical/basal polarity; ISS:UniProtKB.
//
ID   SYNEM_HUMAN             Reviewed;        1565 AA.
AC   O15061; A7E2Y2; Q2TBJ4; Q5NJJ9; Q8TE61; Q8TE62;
DE   RecName: Full=Synemin;
DE   AltName: Full=Desmuslin;
GN   Name=SYNM; Synonyms=DMN, KIAA0353, SYN;
DR   GO; GO:0019215; F:intermediate filament binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IDA:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; IDA:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IDA:UniProtKB.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; TAS:UniProtKB.
//
ID   SYNG1_HUMAN             Reviewed;         258 AA.
AC   Q9H7V2; Q6IA30; Q9H514;
DE   RecName: Full=Synapse differentiation-inducing gene protein 1;
DE            Short=SynDIG1;
DE   AltName: Full=Dispanin subfamily C member 2;
DE            Short=DSPC2;
DE   AltName: Full=Transmembrane protein 90B;
GN   Name=SYNDIG1; Synonyms=C20orf39, TMEM90B;
DR   GO; GO:0035254; F:glutamate receptor binding; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IDA:UniProtKB.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
DR   GO; GO:0097091; P:synaptic vesicle clustering; ISS:UniProtKB.
//
ID   SYNJ1_HUMAN             Reviewed;        1573 AA.
AC   O43426; O43425; O94984; Q4KMR1;
DE   RecName: Full=Synaptojanin-1;
DE            EC=3.1.3.36;
DE   AltName: Full=Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1;
GN   Name=SYNJ1; Synonyms=KIAA0910;
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
//
ID   SYNJ2_HUMAN             Reviewed;        1496 AA.
AC   O15056; Q5TA13; Q5TA16; Q5TA19; Q86XK0; Q8IZA8; Q9H226;
DE   RecName: Full=Synaptojanin-2;
DE            EC=3.1.3.36;
DE   AltName: Full=Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2;
GN   Name=SYNJ2; Synonyms=KIAA0348;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   SYNM_HUMAN              Reviewed;         477 AA.
AC   Q96I59; G3V178;
DE   RecName: Full=Probable asparagine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.22;
DE   AltName: Full=Asparaginyl-tRNA synthetase;
DE            Short=AsnRS;
DE   Flags: Precursor;
GN   Name=NARS2;
DR   GO; GO:0004816; F:asparagine-tRNA ligase activity; ISS:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006421; P:asparaginyl-tRNA aminoacylation; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYNP2_HUMAN             Reviewed;        1093 AA.
AC   Q9UMS6; B2RWP6; B2Y8J9; Q9UK89; S5XAM4;
DE   RecName: Full=Synaptopodin-2;
DE   AltName: Full=Genethonin-2;
DE   AltName: Full=Myopodin;
GN   Name=SYNPO2;
DR   GO; GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.
DR   GO; GO:0051371; F:muscle alpha-actinin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   SYNPO_HUMAN             Reviewed;         929 AA.
AC   Q8N3V7; A5PKZ8; D3DQG8; O15271; Q9UPX1;
DE   RecName: Full=Synaptopodin;
GN   Name=SYNPO; Synonyms=KIAA1029;
DR   GO; GO:0003779; F:actin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032233; P:positive regulation of actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; IEA:Ensembl.
//
ID   SYNPR_HUMAN             Reviewed;         265 AA.
AC   Q8TBG9; B2R675; G5E9W4;
DE   RecName: Full=Synaptoporin;
GN   Name=SYNPR;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   SYNRG_HUMAN             Reviewed;        1314 AA.
AC   Q9UMZ2; A8MWU4; B7ZKZ2; B7ZKZ3; Q17RI2; Q5BKU5; Q6ZT17;
DE   RecName: Full=Synergin gamma;
DE   AltName: Full=AP1 subunit gamma-binding protein 1;
DE   AltName: Full=Gamma-synergin;
GN   Name=SYNRG; Synonyms=AP1GBP1, SYNG;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; TAS:ProtInc.
//
ID   SYP2L_HUMAN             Reviewed;         977 AA.
AC   Q9H987; A5PKV9; Q68A20;
DE   RecName: Full=Synaptopodin 2-like protein;
GN   Name=SYNPO2L;
//
ID   SYPH_HUMAN              Reviewed;         313 AA.
AC   P08247; B2R7L6; Q6P2F7;
DE   RecName: Full=Synaptophysin;
DE   AltName: Full=Major synaptic vesicle protein p38;
GN   Name=SYP;
DR   GO; GO:0015485; F:cholesterol binding; IDA:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; ISS:UniProtKB.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0048168; P:regulation of neuronal synaptic plasticity; IBA:RefGenome.
DR   GO; GO:2000474; P:regulation of opioid receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; ISS:UniProtKB.
DR   GO; GO:0016188; P:synaptic vesicle maturation; NAS:UniProtKB.
DR   GO; GO:0048499; P:synaptic vesicle membrane organization; NAS:UniProtKB.
//
ID   SYPL1_HUMAN             Reviewed;         259 AA.
AC   Q16563; A4D0R2; Q96AR8;
DE   RecName: Full=Synaptophysin-like protein 1;
DE   AltName: Full=Pantophysin;
GN   Name=SYPL1; Synonyms=SYPL;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   SYPL2_HUMAN             Reviewed;         272 AA.
AC   Q5VXT5; A8K0E8; A8KAL7; I0IT67; Q6ZMX1;
DE   RecName: Full=Synaptophysin-like protein 2;
GN   Name=SYPL2;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   SYPM_HUMAN              Reviewed;         475 AA.
AC   Q7L3T8; A8K0W4; Q9H6S5; Q9UFT1;
DE   RecName: Full=Probable proline--tRNA ligase, mitochondrial;
DE            EC=6.1.1.15;
DE   AltName: Full=Prolyl-tRNA synthetase;
DE            Short=ProRS;
DE   Flags: Precursor;
GN   Name=PARS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004827; F:proline-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006433; P:prolyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYQ_HUMAN               Reviewed;         775 AA.
AC   P47897;
DE   RecName: Full=Glutamine--tRNA ligase;
DE            EC=6.1.1.18;
DE   AltName: Full=Glutaminyl-tRNA synthetase;
DE            Short=GlnRS;
GN   Name=QARS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004819; F:glutamine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006425; P:glutaminyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYRC_HUMAN              Reviewed;         660 AA.
AC   P54136; B2RBS9; Q53GY4; Q9BWA1;
DE   RecName: Full=Arginine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.19;
DE   AltName: Full=Arginyl-tRNA synthetase;
DE            Short=ArgRS;
GN   Name=RARS;
DR   GO; GO:0034618; F:arginine binding; IEA:Ensembl.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000049; F:tRNA binding; IEA:Ensembl.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYRM_HUMAN              Reviewed;         578 AA.
AC   Q5T160; B2RDT7; Q96FU5; Q9H8K8;
DE   RecName: Full=Probable arginine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.19;
DE   AltName: Full=Arginyl-tRNA synthetase;
DE            Short=ArgRS;
DE   Flags: Precursor;
GN   Name=RARS2; Synonyms=RARSL;
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYS1_HUMAN              Reviewed;         156 AA.
AC   Q8N2H4; C9JFB3; E1P620; Q5QPU7; Q96SD8; Q9BQZ2; Q9BQZ4; Q9H1F7;
DE   RecName: Full=Protein SYS1 homolog;
GN   Name=SYS1; Synonyms=C20orf169;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   SYSC_HUMAN              Reviewed;         514 AA.
AC   P49591; B2R6Y9; Q5T5C8; Q9NSE3;
DE   RecName: Full=Serine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.11;
DE   AltName: Full=Seryl-tRNA synthetase;
DE            Short=SerRS;
DE   AltName: Full=Seryl-tRNA(Ser/Sec) synthetase;
GN   Name=SARS; Synonyms=SERS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0004828; F:serine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0097056; P:selenocysteinyl-tRNA(Sec) biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0008033; P:tRNA processing; TAS:ProtInc.
//
ID   SYSM_HUMAN              Reviewed;         518 AA.
AC   Q9NP81; A6NHW7; B4DE10; Q9BVP3;
DE   RecName: Full=Serine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.11;
DE   AltName: Full=SerRSmt;
DE   AltName: Full=Seryl-tRNA synthetase;
DE            Short=SerRS;
DE   AltName: Full=Seryl-tRNA(Ser/Sec) synthetase;
DE   Flags: Precursor;
GN   Name=SARS2; Synonyms=SARSM;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004828; F:serine-tRNA ligase activity; ISS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0097056; P:selenocysteinyl-tRNA(Sec) biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006434; P:seryl-tRNA aminoacylation; ISS:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYT10_HUMAN             Reviewed;         523 AA.
AC   Q6XYQ8; Q495U2;
DE   RecName: Full=Synaptotagmin-10;
DE   AltName: Full=Synaptotagmin X;
DE            Short=SytX;
GN   Name=SYT10;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0017158; P:regulation of calcium ion-dependent exocytosis; IEA:InterPro.
//
ID   SYT11_HUMAN             Reviewed;         431 AA.
AC   Q9BT88; Q14998; Q5W0D4; Q68CT5; Q8IXU3; Q96SU2;
DE   RecName: Full=Synaptotagmin-11;
DE   AltName: Full=Synaptotagmin XI;
DE            Short=SytXI;
GN   Name=SYT11; Synonyms=KIAA0080;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   SYT12_HUMAN             Reviewed;         421 AA.
AC   Q8IV01;
DE   RecName: Full=Synaptotagmin-12;
DE   AltName: Full=Synaptotagmin XII;
DE            Short=SytXII;
GN   Name=SYT12;
//
ID   SYT13_HUMAN             Reviewed;         426 AA.
AC   Q7L8C5; A8K4P4; D3DQP1; Q9BQS3; Q9H041; Q9P2C0;
DE   RecName: Full=Synaptotagmin-13;
DE   AltName: Full=Synaptotagmin XIII;
DE            Short=SytXIII;
GN   Name=SYT13; Synonyms=KIAA1427;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:Ensembl.
//
ID   SYT14_HUMAN             Reviewed;         555 AA.
AC   Q8NB59; B1AJU0; B1AJU1; F5H426; Q5THX7; Q707N3; Q707N4; Q707N5;
AC   Q707N6; Q707N7;
DE   RecName: Full=Synaptotagmin-14;
DE   AltName: Full=Synaptotagmin XIV;
DE            Short=SytXIV;
GN   Name=SYT14;
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   SYT15_HUMAN             Reviewed;         421 AA.
AC   Q9BQS2; A5D6W8; Q5VY53; Q5VY55; Q7Z439; Q7Z440;
DE   RecName: Full=Synaptotagmin-15;
DE   AltName: Full=Chr10Syt;
DE   AltName: Full=Synaptotagmin XV;
DE            Short=SytXV;
GN   Name=SYT15;
//
ID   SYT16_HUMAN             Reviewed;         645 AA.
AC   Q17RD7; B7ZL60; C9J8I3; Q707N2; Q7Z441; Q8IUU0; Q9BQR8;
DE   RecName: Full=Synaptotagmin-16;
DE   AltName: Full=Chr14Syt;
DE   AltName: Full=Synaptotagmin 14-like protein;
DE   AltName: Full=Synaptotagmin XIV-related protein;
GN   Name=SYT16; Synonyms=STREP14, SYT14L, SYT14R;
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IEA:InterPro.
//
ID   SYT17_HUMAN             Reviewed;         474 AA.
AC   Q9BSW7; O43330; Q9NZ18;
DE   RecName: Full=Synaptotagmin-17;
DE   AltName: Full=Protein B/K;
DE   AltName: Full=Synaptotagmin XVII;
DE            Short=SytXVII;
GN   Name=SYT17;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   SYT1_HUMAN              Reviewed;         422 AA.
AC   P21579; Q6AI31;
DE   RecName: Full=Synaptotagmin-1;
DE   AltName: Full=Synaptotagmin I;
DE            Short=SytI;
DE   AltName: Full=p65;
GN   Name=SYT1; Synonyms=SVP65, SYT;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; TAS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR   GO; GO:0050750; F:low-density lipoprotein particle receptor binding; IDA:MGI.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0005543; F:phospholipid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0017075; F:syntaxin-1 binding; TAS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0005513; P:detection of calcium ion; TAS:UniProtKB.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:UniProtKB.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; TAS:UniProtKB.
DR   GO; GO:0017157; P:regulation of exocytosis; TAS:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
DR   GO; GO:0048278; P:vesicle docking; IEA:Ensembl.
//
ID   SYT2_HUMAN              Reviewed;         419 AA.
AC   Q8N9I0; Q496K5; Q8NBE5;
DE   RecName: Full=Synaptotagmin-2;
DE   AltName: Full=Synaptotagmin II;
DE            Short=SytII;
GN   Name=SYT2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   SYT3_HUMAN              Reviewed;         590 AA.
AC   Q9BQG1; Q8N5Z1; Q8N640;
DE   RecName: Full=Synaptotagmin-3;
DE   AltName: Full=Synaptotagmin III;
DE            Short=SytIII;
GN   Name=SYT3;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0031340; P:positive regulation of vesicle fusion; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
//
ID   SYT4_HUMAN              Reviewed;         425 AA.
AC   Q9H2B2; Q9P2K4;
DE   RecName: Full=Synaptotagmin-4;
DE   AltName: Full=Synaptotagmin IV;
DE            Short=SytIV;
GN   Name=SYT4; Synonyms=KIAA1342;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR   GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0031339; P:negative regulation of vesicle fusion; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
//
ID   SYT5_HUMAN              Reviewed;         386 AA.
AC   O00445; B3KWJ8; Q86X72;
DE   RecName: Full=Synaptotagmin-5;
DE   AltName: Full=Synaptotagmin V;
DE            Short=SytV;
GN   Name=SYT5;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:InterPro.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   SYT6_HUMAN              Reviewed;         510 AA.
AC   Q5T7P8; B1AMB8; B3KPK1;
DE   RecName: Full=Synaptotagmin-6;
DE   AltName: Full=Synaptotagmin VI;
DE            Short=SytVI;
GN   Name=SYT6;
DR   GO; GO:0030276; F:clathrin binding; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0019905; F:syntaxin binding; IDA:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0060478; P:acrosomal vesicle exocytosis; IMP:BHF-UCL.
//
ID   SYT7_HUMAN              Reviewed;         403 AA.
AC   O43581; F5GZU9; Q08AH6;
DE   RecName: Full=Synaptotagmin-7;
DE   AltName: Full=IPCA-7;
DE   AltName: Full=Prostate cancer-associated protein 7;
DE   AltName: Full=Synaptotagmin VII;
DE            Short=SytVII;
GN   Name=SYT7; Synonyms=PCANAP7;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0001778; P:plasma membrane repair; IEA:Ensembl.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
//
ID   SYT8_HUMAN              Reviewed;         401 AA.
AC   Q8NBV8; A6NFJ4; Q9NSV9;
DE   RecName: Full=Synaptotagmin-8;
DE   AltName: Full=Synaptotagmin VIII;
DE            Short=SytVIII;
GN   Name=SYT8;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
//
ID   SYT9_HUMAN              Reviewed;         491 AA.
AC   Q86SS6;
DE   RecName: Full=Synaptotagmin-9;
DE   AltName: Full=Synaptotagmin IX;
DE            Short=SytIX;
GN   Name=SYT9;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; IEA:Ensembl.
//
ID   SYTC2_HUMAN             Reviewed;         802 AA.
AC   A2RTX5; B2RMP7; Q6B0A1; Q6IS76; Q96LW3; Q96MP4;
DE   RecName: Full=Probable threonine--tRNA ligase 2, cytoplasmic;
DE            EC=6.1.1.3;
DE   AltName: Full=Threonyl-tRNA synthetase;
DE            Short=ThrRS;
DE   AltName: Full=Threonyl-tRNA synthetase-like protein 2;
GN   Name=TARSL2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004829; F:threonine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006435; P:threonyl-tRNA aminoacylation; IEA:InterPro.
//
ID   SYTC_HUMAN              Reviewed;         723 AA.
AC   P26639; A8K8I1; B4DEG8; Q96FP5; Q9BWA6;
DE   RecName: Full=Threonine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.3;
DE   AltName: Full=Threonyl-tRNA synthetase;
DE            Short=ThrRS;
GN   Name=TARS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0004829; F:threonine-tRNA ligase activity; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006435; P:threonyl-tRNA aminoacylation; NAS:UniProtKB.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYTL2_HUMAN             Reviewed;         934 AA.
AC   Q9HCH5; B3KRS3; B4DJT5; B4DKW3; B4DQ26; B7SA85; B7ZLX6; B7ZLX7;
AC   Q2YDA7; Q6TV07; Q6ZN59; Q6ZVC5; Q8ND34; Q96BJ2; Q9H768; Q9NXM1;
DE   RecName: Full=Synaptotagmin-like protein 2;
DE   AltName: Full=Breast cancer-associated antigen SGA-72M;
DE   AltName: Full=Exophilin-4;
GN   Name=SYTL2; Synonyms=KIAA1597, SGA72M, SLP2, SLP2A;
DR   GO; GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IMP:UniProtKB.
DR   GO; GO:0001786; F:phosphatidylserine binding; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IDA:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   SYTL1_HUMAN             Reviewed;         562 AA.
AC   Q8IYJ3; Q5SSC9; Q96BB6; Q96GU6; Q96S89; Q96SI0;
DE   RecName: Full=Synaptotagmin-like protein 1;
DE   AltName: Full=Exophilin-7;
DE   AltName: Full=Protein JFC1;
GN   Name=SYTL1; Synonyms=SLP1; ORFNames=SB146;
DR   GO; GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   SYTL3_HUMAN             Reviewed;         610 AA.
AC   Q4VX76; Q496J4; Q496J6; Q5U3B9;
DE   RecName: Full=Synaptotagmin-like protein 3;
DE   AltName: Full=Exophilin-6;
GN   Name=SYTL3; Synonyms=SLP3;
DR   GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   SYTL4_HUMAN             Reviewed;         671 AA.
AC   Q96C24; Q5H9J3; Q5JPG8; Q8N9P4; Q9H4R0; Q9H4R1;
DE   RecName: Full=Synaptotagmin-like protein 4;
DE   AltName: Full=Exophilin-2;
DE   AltName: Full=Granuphilin;
GN   Name=SYTL4;
DR   GO; GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB.
//
ID   SYTL5_HUMAN             Reviewed;         730 AA.
AC   Q8TDW5; A2RRF2;
DE   RecName: Full=Synaptotagmin-like protein 5;
GN   Name=SYTL5; Synonyms=SLP5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   SYTM_HUMAN              Reviewed;         718 AA.
AC   Q9BW92; Q53GW7; Q96I50; Q9H9V2;
DE   RecName: Full=Threonine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.3;
DE   AltName: Full=Threonyl-tRNA synthetase;
DE            Short=ThrRS;
DE   AltName: Full=Threonyl-tRNA synthetase-like 1;
DE   Flags: Precursor;
GN   Name=TARS2; Synonyms=TARSL1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004829; F:threonine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0070159; P:mitochondrial threonyl-tRNA aminoacylation; TAS:BHF-UCL.
DR   GO; GO:0006435; P:threonyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SYUA_HUMAN              Reviewed;         140 AA.
AC   P37840; A8K2A4; Q13701; Q4JHI3; Q6IAU6;
DE   RecName: Full=Alpha-synuclein;
DE   AltName: Full=Non-A beta component of AD amyloid;
DE   AltName: Full=Non-A4 component of amyloid precursor;
DE            Short=NACP;
GN   Name=SNCA; Synonyms=NACP, PARK1;
DR   GO; GO:0043014; F:alpha-tubulin binding; IPI:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005507; F:copper ion binding; IDA:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045502; F:dynein binding; IPI:UniProtKB.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0051219; F:phosphoprotein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048156; F:tau protein binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0048148; P:behavioral response to cocaine; IEA:Ensembl.
DR   GO; GO:0071280; P:cellular response to copper ion; IDA:UniProtKB.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; TAS:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0042416; P:dopamine biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0051583; P:dopamine uptake involved in synaptic transmission; TAS:UniProtKB.
DR   GO; GO:0043206; P:extracellular fibril organization; TAS:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0001774; P:microglial cell activation; IEA:Ensembl.
DR   GO; GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IEA:Ensembl.
DR   GO; GO:0007006; P:mitochondrial membrane organization; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045963; P:negative regulation of dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0051585; P:negative regulation of dopamine uptake involved in synaptic transmission; IDA:UniProtKB.
DR   GO; GO:0045920; P:negative regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IDA:UniProtKB.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IDA:BHF-UCL.
DR   GO; GO:0032769; P:negative regulation of monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0051622; P:negative regulation of norepinephrine uptake; IDA:UniProtKB.
DR   GO; GO:0010642; P:negative regulation of platelet-derived growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051612; P:negative regulation of serotonin uptake; IDA:UniProtKB.
DR   GO; GO:0070495; P:negative regulation of thrombin receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032410; P:negative regulation of transporter activity; IDA:UniProtKB.
DR   GO; GO:0006638; P:neutral lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:Ensembl.
DR   GO; GO:0045807; P:positive regulation of endocytosis; IDA:UniProtKB.
DR   GO; GO:0060732; P:positive regulation of inositol phosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001956; P:positive regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:UniProtKB.
DR   GO; GO:0031648; P:protein destabilization; IDA:UniProtKB.
DR   GO; GO:0031623; P:receptor internalization; IDA:UniProtKB.
DR   GO; GO:0050812; P:regulation of acyl-CoA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0014059; P:regulation of dopamine secretion; TAS:UniProtKB.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0014048; P:regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0040012; P:regulation of locomotion; IEA:Ensembl.
DR   GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0043030; P:regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0010517; P:regulation of phospholipase activity; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0034341; P:response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0070555; P:response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0010040; P:response to iron(II) ion; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0032026; P:response to magnesium ion; IDA:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
//
ID   SYUB_HUMAN              Reviewed;         134 AA.
AC   Q16143; Q6IAX7;
DE   RecName: Full=Beta-synuclein;
GN   Name=SNCB;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0004859; F:phospholipase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0042417; P:dopamine metabolic process; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   SYUG_HUMAN              Reviewed;         127 AA.
AC   O76070; O15104; Q96P61;
DE   RecName: Full=Gamma-synuclein;
DE   AltName: Full=Breast cancer-specific gene 1 protein;
DE   AltName: Full=Persyn;
DE   AltName: Full=Synoretin;
DE            Short=SR;
GN   Name=SNCG; Synonyms=BCSG1, PERSYN, PRSN;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0002118; P:aggressive behavior; IEA:Ensembl.
DR   GO; GO:0071464; P:cellular response to hydrostatic pressure; IEA:Ensembl.
DR   GO; GO:0014059; P:regulation of dopamine secretion; IEA:Ensembl.
DR   GO; GO:0046928; P:regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   SYVC_HUMAN              Reviewed;        1264 AA.
AC   P26640; B0V1N1; Q5JQ90; Q96E77; Q9UQM2;
DE   RecName: Full=Valine--tRNA ligase;
DE            EC=6.1.1.9;
DE   AltName: Full=Protein G7a;
DE   AltName: Full=Valyl-tRNA synthetase;
DE            Short=ValRS;
GN   Name=VARS; Synonyms=G7A, VARS2;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004832; F:valine-tRNA ligase activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0006438; P:valyl-tRNA aminoacylation; IEA:InterPro.
//
ID   SYVM_HUMAN              Reviewed;        1063 AA.
AC   Q5ST30; A2ABL7; B4DET4; B4E3P5; F5GXJ0; F5H323; Q2M2A0; Q59FI1;
AC   Q5SQ96; Q5SS98; Q6DKJ5; Q6ZV24; Q96GN2; Q96H77; Q96Q02; Q9H6R2;
AC   Q9UFH7;
DE   RecName: Full=Valine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.9;
DE   AltName: Full=Valyl-tRNA synthetase;
DE            Short=ValRS;
DE   AltName: Full=Valyl-tRNA synthetase-like;
DE   Flags: Precursor;
GN   Name=VARS2; Synonyms=KIAA1885, VARS2L, VARSL;
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004832; F:valine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0006438; P:valyl-tRNA aminoacylation; IEA:InterPro.
//
ID   SYVN1_HUMAN             Reviewed;         617 AA.
AC   Q86TM6; Q8N3K3; Q8N6E8; Q96JL5; Q96PK3;
DE   RecName: Full=E3 ubiquitin-protein ligase synoviolin;
DE            EC=6.3.2.-;
DE   AltName: Full=Synovial apoptosis inhibitor 1;
DE   Flags: Precursor;
GN   Name=SYVN1; Synonyms=HRD1, KIAA1810;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:1902236; P:negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   SYWC_HUMAN              Reviewed;         471 AA.
AC   P23381; A6NGN1; A6NID3; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3;
DE   RecName: Full=Tryptophan--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.2;
DE   AltName: Full=Interferon-induced protein 53;
DE            Short=IFP53;
DE   AltName: Full=Tryptophanyl-tRNA synthetase;
DE            Short=TrpRS;
DE            Short=hWRS;
DE   Contains:
DE     RecName: Full=T1-TrpRS;
DE   Contains:
DE     RecName: Full=T2-TrpRS;
GN   Name=WARS; Synonyms=IFI53, WRS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004830; F:tryptophan-tRNA ligase activity; NAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045765; P:regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; NAS:UniProtKB.
//
ID   SYWM_HUMAN              Reviewed;         360 AA.
AC   Q9UGM6; B1ALR1; B2R9D4; Q53FT4; Q5VUD2; Q86TQ0;
DE   RecName: Full=Tryptophan--tRNA ligase, mitochondrial;
DE            EC=6.1.1.2;
DE   AltName: Full=(Mt)TrpRS;
DE   AltName: Full=Tryptophanyl-tRNA synthetase;
DE            Short=TrpRS;
DE   Flags: Precursor;
GN   Name=WARS2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004830; F:tryptophan-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   SYYC_HUMAN              Reviewed;         528 AA.
AC   P54577; B3KWK4; D3DPQ4; O43276; Q53EN1;
DE   RecName: Full=Tyrosine--tRNA ligase, cytoplasmic;
DE            EC=6.1.1.1;
DE   AltName: Full=Tyrosyl-tRNA synthetase;
DE            Short=TyrRS;
DE   Contains:
DE     RecName: Full=Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed;
GN   Name=YARS;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005153; F:interleukin-8 receptor binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:ProtInc.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004831; F:tyrosine-tRNA ligase activity; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
DR   GO; GO:0006437; P:tyrosyl-tRNA aminoacylation; TAS:ProtInc.
//
ID   SYYM_HUMAN              Reviewed;         477 AA.
AC   Q9Y2Z4; D3DUW8; Q9H817;
DE   RecName: Full=Tyrosine--tRNA ligase, mitochondrial;
DE            EC=6.1.1.1;
DE   AltName: Full=Tyrosyl-tRNA synthetase;
DE            Short=TyrRS;
DE   Flags: Precursor;
GN   Name=YARS2; ORFNames=CGI-04;
DR   GO; GO:0005524; F:ATP binding; TAS:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0000049; F:tRNA binding; IDA:BHF-UCL.
DR   GO; GO:0072545; F:tyrosine binding; IDA:BHF-UCL.
DR   GO; GO:0004831; F:tyrosine-tRNA ligase activity; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0070184; P:mitochondrial tyrosyl-tRNA aminoacylation; IMP:BHF-UCL.
DR   GO; GO:0006412; P:translation; NAS:UniProtKB.
DR   GO; GO:0043039; P:tRNA aminoacylation; IDA:BHF-UCL.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; TAS:Reactome.
//
ID   SZRD1_HUMAN             Reviewed;         152 AA.
AC   Q7Z422; A8MXJ2; Q7Z424; Q8IVM2; Q8TBV3; Q9Y403;
DE   RecName: Full=SUZ domain-containing protein 1;
DE   AltName: Full=Putative MAPK-activating protein PM18/PM20/PM22;
GN   Name=SZRD1; Synonyms=C1orf144;
//
ID   T106A_HUMAN             Reviewed;         262 AA.
AC   Q96A25; A8K2X2;
DE   RecName: Full=Transmembrane protein 106A;
GN   Name=TMEM106A;
//
ID   SZT2_HUMAN              Reviewed;        3432 AA.
AC   Q5T011; A0PJK5; A7E2X4; O75055; Q5JUY7; Q5T012; Q5XKC7; Q6ZNI8;
AC   Q6ZT24; Q7Z636; Q8NAY9; Q9H5H7; Q9UFQ8;
DE   RecName: Full=Protein SZT2;
DE   AltName: Full=Seizure threshold 2 protein homolog;
GN   Name=SZT2; Synonyms=C1orf84, KIAA0467;
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProt.
DR   GO; GO:0021540; P:corpus callosum morphogenesis; IMP:UniProt.
DR   GO; GO:0009790; P:embryo development; ISS:UniProt.
DR   GO; GO:0043473; P:pigmentation; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; ISS:UniProt.
DR   GO; GO:1901668; P:regulation of superoxide dismutase activity; ISS:UniProt.
//
ID   T106B_HUMAN             Reviewed;         274 AA.
AC   Q9NUM4; A4D108; Q53FL9; Q8N4L0;
DE   RecName: Full=Transmembrane protein 106B;
GN   Name=TMEM106B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0048813; P:dendrite morphogenesis; IMP:UniProtKB.
DR   GO; GO:0032418; P:lysosome localization; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   T106C_HUMAN             Reviewed;         250 AA.
AC   Q9BVX2; B2R998; B7Z5M4; Q3B761;
DE   RecName: Full=Transmembrane protein 106C;
DE   AltName: Full=Endoplasmic reticulum membrane protein overexpressed in cancer;
GN   Name=TMEM106C; Synonyms=EMOC;
//
ID   T10B_HUMAN              Reviewed;         103 AA.
AC   Q9Y5J6; Q96FF3;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim10 B;
DE   AltName: Full=Fracture callus protein 1;
DE   AltName: Full=FxC1;
DE   AltName: Full=Mitochondrial import inner membrane translocase subunit Tim9 B;
DE   AltName: Full=TIMM10B;
DE            Short=Tim10b;
GN   Name=TIMM10B; Synonyms=FXC1, TIM9B, TIMM9B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   T10IP_HUMAN             Reviewed;         556 AA.
AC   Q3SY00; Q3SXZ9; Q3SY01; Q96M26;
DE   RecName: Full=Testis-specific protein 10-interacting protein;
DE   AltName: Full=Tsga10-interacting protein;
GN   Name=TSGA10IP;
//
ID   T11L2_HUMAN             Reviewed;         519 AA.
AC   Q8N4U5; B2RA65;
DE   RecName: Full=T-complex protein 11-like protein 2;
GN   Name=TCP11L2;
//
ID   T11X1_HUMAN             Reviewed;         312 AA.
AC   B4DZS4;
DE   RecName: Full=T-complex protein 11 X-linked protein 1;
GN   Name=TCP11X1;
//
ID   T11X2_HUMAN             Reviewed;         407 AA.
AC   Q5H9J9;
DE   RecName: Full=T-complex protein 11 X-linked protein 2;
GN   Name=TCP11X2;
//
ID   T11L1_HUMAN             Reviewed;         509 AA.
AC   Q9NUJ3; D3DR01; Q8IVX4;
DE   RecName: Full=T-complex protein 11-like protein 1;
GN   Name=TCP11L1;
//
ID   T120A_HUMAN             Reviewed;         343 AA.
AC   Q9BXJ8; Q86TE9; Q8N6P1;
DE   RecName: Full=Transmembrane protein 120A;
DE   AltName: Full=Transmembrane protein induced by tumor necrosis factor alpha;
GN   Name=TMEM120A; Synonyms=TMPIT;
//
ID   T120B_HUMAN             Reviewed;         339 AA.
AC   A0PK00; A0PK01; B3KX33;
DE   RecName: Full=Transmembrane protein 120B;
GN   Name=TMEM120B;
//
ID   T126A_HUMAN             Reviewed;         195 AA.
AC   Q9H061; B2R570; E9PI16;
DE   RecName: Full=Transmembrane protein 126A;
GN   Name=TMEM126A;
DR   GO; GO:0021554; P:optic nerve development; IMP:BHF-UCL.
//
ID   T126B_HUMAN             Reviewed;         230 AA.
AC   Q8IUX1; A8K535; A8MSS0; Q32Q09; Q8WVU3; Q96EP3; Q9NZ29;
DE   RecName: Full=Complex I assembly factor TMEM126B, mitochondrial;
DE   AltName: Full=Transmembrane protein 126B;
GN   Name=TMEM126B; ORFNames=HT007;
//
ID   T131L_HUMAN             Reviewed;        1609 AA.
AC   A2VDJ0; B3KRV3; Q7LGA7; Q86Y92; Q8WU56; Q9H065; Q9Y2D7;
DE   RecName: Full=Transmembrane protein 131-like;
DE   Flags: Precursor;
GN   Name=KIAA0922; Synonyms=TMEM131L;
//
ID   T132A_HUMAN             Reviewed;        1023 AA.
AC   Q24JP5; Q69YU7; Q86VZ8; Q86W97; Q9H8K3; Q9HCI9; Q9NWY0;
DE   RecName: Full=Transmembrane protein 132A;
DE   AltName: Full=HSPA5-binding protein 1;
DE   Flags: Precursor;
GN   Name=TMEM132A; Synonyms=HSPA5BP1, KIAA1583;
//
ID   T132C_HUMAN             Reviewed;        1108 AA.
AC   Q8N3T6; Q69YX8;
DE   RecName: Full=Transmembrane protein 132C;
DE   Flags: Precursor;
GN   Name=TMEM132C;
//
ID   T132B_HUMAN             Reviewed;        1078 AA.
AC   Q14DG7; A2RRG8; Q8NA73; Q96JN9; Q96PY1;
DE   RecName: Full=Transmembrane protein 132B;
GN   Name=TMEM132B; Synonyms=KIAA1786, KIAA1906;
//
ID   T132D_HUMAN             Reviewed;        1099 AA.
AC   Q14C87; Q14C96; Q76M59; Q8N1W9; Q8N3Q5; Q8TF57;
DE   RecName: Full=Transmembrane protein 132D;
DE   AltName: Full=Mature oligodendrocytes transmembrane protein;
DE            Short=Mature OL transmembrane protein;
DE   Flags: Precursor;
GN   Name=TMEM132D; Synonyms=HBE120, KIAA1944, MOLT;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   T132E_HUMAN             Reviewed;         984 AA.
AC   Q6IEE7; Q8WUF4; Q8WVA5;
DE   RecName: Full=Transmembrane protein 132E;
DE   Flags: Precursor;
GN   Name=TMEM132E;
//
ID   T150A_HUMAN             Reviewed;         271 AA.
AC   Q86TG1; A8K764; B7WPQ9; D6W5L2; Q8N2R6;
DE   RecName: Full=Transmembrane protein 150A;
DE   AltName: Full=Transmembrane protein 150;
DE   Flags: Precursor;
GN   Name=TMEM150A; Synonyms=TMEM150;
DR   GO; GO:0009056; P:catabolic process; IEA:Ensembl.
//
ID   T150B_HUMAN             Reviewed;         233 AA.
AC   A6NC51; B7ZW71;
DE   RecName: Full=Transmembrane protein 150B;
DE   AltName: Full=Transmembrane protein 224;
DE   Flags: Precursor;
GN   Name=TMEM150B; Synonyms=TMEM224;
//
ID   T150C_HUMAN             Reviewed;         249 AA.
AC   B9EJG8; B7Z4J5; B7Z4L3; B7Z692; B7Z6X6;
DE   RecName: Full=Transmembrane protein 150C;
GN   Name=TMEM150C;
//
ID   T151A_HUMAN             Reviewed;         468 AA.
AC   Q8N4L1; Q8ND14;
DE   RecName: Full=Transmembrane protein 151A;
GN   Name=TMEM151A; Synonyms=TMEM151;
//
ID   T151B_HUMAN             Reviewed;         566 AA.
AC   Q8IW70; Q5T9V7;
DE   RecName: Full=Transmembrane protein 151B;
DE   AltName: Full=Transmembrane protein 193;
GN   Name=TMEM151B; Synonyms=C6orf137, TMEM193;
//
ID   T161A_HUMAN             Reviewed;         479 AA.
AC   Q9NX61; B3KUE0; G5E9M6; Q7L2Y1;
DE   RecName: Full=Transmembrane protein 161A;
DE   AltName: Full=Adaptive response to oxidative stress protein 29;
DE            Short=AROS-29;
DE   Flags: Precursor;
GN   Name=TMEM161A; ORFNames=UNQ582/PRO1152;
DR   GO; GO:0034599; P:cellular response to oxidative stress; IDA:BHF-UCL.
DR   GO; GO:0034644; P:cellular response to UV; IDA:BHF-UCL.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:BHF-UCL.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; IDA:BHF-UCL.
//
ID   T161B_HUMAN             Reviewed;         487 AA.
AC   Q8NDZ6; Q5CZH7; Q6UWQ6;
DE   RecName: Full=Transmembrane protein 161B;
GN   Name=TMEM161B; ORFNames=UNQ679/PRO1313;
//
ID   T170A_HUMAN             Reviewed;         144 AA.
AC   Q8WVE7; B2R4R3; B4DPS4; D3DUK2; Q7Z6F3;
DE   RecName: Full=Transmembrane protein 170A;
GN   Name=TMEM170A; Synonyms=TMEM170;
//
ID   T170B_HUMAN             Reviewed;         132 AA.
AC   Q5T4T1;
DE   RecName: Full=Transmembrane protein 170B;
GN   Name=TMEM170B;
//
ID   T176B_HUMAN             Reviewed;         270 AA.
AC   Q3YBM2; B2RDK2; D3DWZ7; E9PAV4; Q5BJI2; Q9BT42; Q9Y609;
DE   RecName: Full=Transmembrane protein 176B;
DE   AltName: Full=Protein LR8;
GN   Name=TMEM176B; Synonyms=LR8;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:2001199; P:negative regulation of dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
//
ID   T176A_HUMAN             Reviewed;         235 AA.
AC   Q96HP8; D3DX00; Q9NYC7;
DE   RecName: Full=Transmembrane protein 176A;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 112;
GN   Name=TMEM176A; Synonyms=HCA112;
DR   GO; GO:2001199; P:negative regulation of dendritic cell differentiation; IEA:Ensembl.
//
ID   T178A_HUMAN             Reviewed;         297 AA.
AC   Q8NBL3; Q6UWI6; Q8N6N4;
DE   RecName: Full=Transmembrane protein 178A;
DE   Flags: Precursor;
GN   Name=TMEM178A; Synonyms=TMEM178; ORFNames=PSEC0131, UNQ5926/PRO19820;
//
ID   T178B_HUMAN             Reviewed;         294 AA.
AC   H3BS89;
DE   RecName: Full=Transmembrane protein 178B;
DE   Flags: Precursor;
GN   Name=TMEM178B;
//
ID   T179A_HUMAN             Reviewed;         233 AA.
AC   Q6ZVK1;
DE   RecName: Full=Transmembrane protein 179;
DE   AltName: Full=Transmembrane protein 179A;
GN   Name=TMEM179; Synonyms=C14orf90, TMEM179A;
//
ID   T179B_HUMAN             Reviewed;         219 AA.
AC   Q7Z7N9;
DE   RecName: Full=Transmembrane protein 179B;
GN   Name=TMEM179B;
//
ID   T183A_HUMAN             Reviewed;         376 AA.
AC   Q8IXX5; A8K5W1; Q6NW15; Q96E06;
DE   RecName: Full=Transmembrane protein 183A;
GN   Name=TMEM183A; Synonyms=C1orf37;
//
ID   T183B_HUMAN             Reviewed;         376 AA.
AC   Q1AE95; Q1AE97;
DE   RecName: Full=Transmembrane protein 183B;
GN   Name=TMEM183B; Synonyms=C1orf37-dup;
//
ID   T184A_HUMAN             Reviewed;         413 AA.
AC   Q6ZMB5; Q8TBQ6;
DE   RecName: Full=Transmembrane protein 184A;
GN   Name=TMEM184A;
DR   GO; GO:0018992; P:germ-line sex determination; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0051046; P:regulation of secretion; IEA:Ensembl.
//
ID   T184B_HUMAN             Reviewed;         407 AA.
AC   Q9Y519; A8K9D7; Q63HM8; Q7Z421; Q8NBM5; Q9UGT8; Q9UGT9; Q9UGV5;
DE   RecName: Full=Transmembrane protein 184B;
DE   AltName: Full=Putative MAPK-activating protein FM08;
GN   Name=TMEM184B; Synonyms=C22orf5; ORFNames=PSEC0108;
//
ID   T184C_HUMAN             Reviewed;         438 AA.
AC   Q9NVA4; D3DP04; Q86X84; Q969I7; Q9NXM2;
DE   RecName: Full=Transmembrane protein 184C;
DE   AltName: Full=Transmembrane protein 34;
GN   Name=TMEM184C; Synonyms=TMEM34; ORFNames=PRO1355;
//
ID   T185A_HUMAN             Reviewed;         350 AA.
AC   Q8NFB2; B3KTZ3; Q3SYH1; Q96CW3; Q96KE8;
DE   RecName: Full=Transmembrane protein 185A;
DE   AltName: Full=Protein FAM11A;
GN   Name=TMEM185A; Synonyms=CXorf13, FAM11A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   T185B_HUMAN             Reviewed;         350 AA.
AC   Q9H7F4; A8K1G5; Q53T33; Q66K44; Q8IZ77;
DE   RecName: Full=Transmembrane protein 185B;
DE   AltName: Full=Protein FAM11B;
GN   Name=TMEM185B; Synonyms=FAM11B;
//
ID   T191C_HUMAN             Reviewed;         121 AA.
AC   A6NGB0;
DE   RecName: Full=Transmembrane protein 191C;
GN   Name=TMEM191C;
//
ID   T191B_HUMAN             Reviewed;         160 AA.
AC   P0C7N4;
DE   RecName: Full=Transmembrane protein 191B;
GN   Name=TMEM191B;
//
ID   T191A_HUMAN             Reviewed;         160 AA.
AC   Q9H0A3; B2R8E2;
DE   RecName: Full=Transmembrane protein 191A;
GN   Name=TMEM191A;
//
ID   T194A_HUMAN             Reviewed;         444 AA.
AC   O14524; Q17R72; Q68DH0; Q6IQ25;
DE   RecName: Full=Transmembrane protein 194A;
GN   Name=TMEM194A; Synonyms=KIAA0286, TMEM194;
//
ID   T194B_HUMAN             Reviewed;         417 AA.
AC   A6NFY4;
DE   RecName: Full=Transmembrane protein 194B;
GN   Name=TMEM194B;
//
ID   T200A_HUMAN             Reviewed;         491 AA.
AC   Q86VY9; Q96PX5;
DE   RecName: Full=Transmembrane protein 200A;
GN   Name=TMEM200A; Synonyms=KIAA1913; ORFNames=HBE61;
//
ID   T200B_HUMAN             Reviewed;         307 AA.
AC   Q69YZ2; Q6P2G8; Q6P2Q5;
DE   RecName: Full=Transmembrane protein 200B;
DE   AltName: Full=Transmembrane protein TTMA;
DE   AltName: Full=Two transmembrane domain-containing family member B;
GN   Name=TMEM200B; Synonyms=TTMB;
//
ID   T200C_HUMAN             Reviewed;         621 AA.
AC   A6NKL6;
DE   RecName: Full=Transmembrane protein 200C;
DE   AltName: Full=Transmembrane protein TTMA;
DE   AltName: Full=Two transmembrane domain-containing family member A;
GN   Name=TMEM200C; Synonyms=TTMA;
//
ID   T229A_HUMAN             Reviewed;         380 AA.
AC   B2RXF0; A4D0X6;
DE   RecName: Full=Transmembrane protein 229A;
GN   Name=TMEM229A;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   T229B_HUMAN             Reviewed;         167 AA.
AC   Q8NBD8;
DE   RecName: Full=Transmembrane protein 229B;
GN   Name=TMEM229B; Synonyms=C14orf83;
//
ID   T22D1_HUMAN             Reviewed;        1073 AA.
AC   Q15714; B3KRL7; B9EGI0; O00666; Q6AHX5; Q6IBU1; Q8NCN1; Q96JS5;
DE   RecName: Full=TSC22 domain family protein 1;
DE   AltName: Full=Cerebral protein 2;
DE   AltName: Full=Regulatory protein TSC-22;
DE   AltName: Full=TGFB-stimulated clone 22 homolog;
DE   AltName: Full=Transforming growth factor beta-1-induced transcript 4 protein;
GN   Name=TSC22D1; Synonyms=KIAA1994, TGFB1I4, TSC22; ORFNames=hucep-2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   T22D2_HUMAN             Reviewed;         780 AA.
AC   O75157; D3DNI5; Q6PI50; Q9H2Z6; Q9H2Z7; Q9H2Z8;
DE   RecName: Full=TSC22 domain family protein 2;
DE   AltName: Full=TSC22-related-inducible leucine zipper protein 4;
GN   Name=TSC22D2; Synonyms=KIAA0669, TILZ4;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
//
ID   T22D4_HUMAN             Reviewed;         395 AA.
AC   Q9Y3Q8; A4D2C3; D6W5V9;
DE   RecName: Full=TSC22 domain family protein 4;
DE   AltName: Full=TSC22-related-inducible leucine zipper protein 2;
DE   AltName: Full=Tsc-22-like protein THG-1;
GN   Name=TSC22D4; Synonyms=THG1, TILZ2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   T22D3_HUMAN             Reviewed;         134 AA.
AC   Q99576; Q5H9S3; Q5JRI9; Q6FIH6; Q8NAI1; Q8WVB9; Q9UBN5; Q9UG13;
DE   RecName: Full=TSC22 domain family protein 3;
DE   AltName: Full=DSIP-immunoreactive peptide;
DE            Short=Protein DIP;
DE            Short=hDIP;
DE   AltName: Full=Delta sleep-inducing peptide immunoreactor;
DE   AltName: Full=Glucocorticoid-induced leucine zipper protein;
DE            Short=GILZ;
DE   AltName: Full=TSC-22-like protein;
DE   AltName: Full=TSC-22-related protein;
DE            Short=TSC-22R;
GN   Name=TSC22D3; Synonyms=DSIPI, GILZ;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007589; P:body fluid secretion; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0070236; P:negative regulation of activation-induced cell death of T cells; IEA:Ensembl.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   T23O_HUMAN              Reviewed;         406 AA.
AC   P48775; A8K053;
DE   RecName: Full=Tryptophan 2,3-dioxygenase;
DE            Short=TDO;
DE            EC=1.13.11.11;
DE   AltName: Full=Tryptamin 2,3-dioxygenase;
DE   AltName: Full=Tryptophan oxygenase;
DE            Short=TO;
DE            Short=TRPO;
DE   AltName: Full=Tryptophan pyrrolase;
DE   AltName: Full=Tryptophanase;
GN   Name=TDO2; Synonyms=TDO;
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0020037; F:heme binding; IBA:RefGenome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:Ensembl.
DR   GO; GO:0004833; F:tryptophan 2,3-dioxygenase activity; IBA:RefGenome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006569; P:tryptophan catabolic process; TAS:Reactome.
DR   GO; GO:0019442; P:tryptophan catabolic process to acetyl-CoA; IBA:RefGenome.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:UniProtKB-UniPathway.
//
ID   T255B_HUMAN             Reviewed;         326 AA.
AC   Q8WV15;
DE   RecName: Full=Transmembrane protein 255B;
DE   AltName: Full=Protein FAM70B;
GN   Name=TMEM255B; Synonyms=FAM70B;
//
ID   T255A_HUMAN             Reviewed;         349 AA.
AC   Q5JRV8; A8K0W9; B1APR4; B3KPI6; E9PAR3; Q86Y72; Q9NWN8;
DE   RecName: Full=Transmembrane protein 255A;
DE   AltName: Full=Protein FAM70A;
GN   Name=TMEM255A; Synonyms=FAM70A;
//
ID   T2AG_HUMAN              Reviewed;         109 AA.
AC   P52657; A8MYQ7; Q6FGB5;
DE   RecName: Full=Transcription initiation factor IIA subunit 2;
DE   AltName: Full=General transcription factor IIA subunit 2;
DE   AltName: Full=TFIIA p12 subunit;
DE            Short=TFIIA-12;
DE            Short=TFIIAS;
DE   AltName: Full=Transcription initiation factor IIA gamma chain;
DE            Short=TFIIA-gamma;
GN   Name=GTF2A2; Synonyms=TF2A2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0017025; F:TBP-class protein binding; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IDA:BHF-UCL.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   T2EA_HUMAN              Reviewed;         439 AA.
AC   P29083; Q16103;
DE   RecName: Full=General transcription factor IIE subunit 1;
DE   AltName: Full=General transcription factor IIE 56 kDa subunit;
DE   AltName: Full=Transcription initiation factor IIE subunit alpha;
DE            Short=TFIIE-alpha;
GN   Name=GTF2E1; Synonyms=TF2E1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   T2EB_HUMAN              Reviewed;         291 AA.
AC   P29084; D3DSV2; Q9H2B9;
DE   RecName: Full=Transcription initiation factor IIE subunit beta;
DE            Short=TFIIE-beta;
DE   AltName: Full=General transcription factor IIE subunit 2;
GN   Name=GTF2E2; Synonyms=TF2E2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   T2FA_HUMAN              Reviewed;         517 AA.
AC   P35269; B2RCS0; Q9BWN0;
DE   RecName: Full=General transcription factor IIF subunit 1;
DE   AltName: Full=General transcription factor IIF 74 kDa subunit;
DE   AltName: Full=Transcription initiation factor IIF subunit alpha;
DE            Short=TFIIF-alpha;
DE   AltName: Full=Transcription initiation factor RAP74;
GN   Name=GTF2F1; Synonyms=RAP74;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0019211; F:phosphatase activator activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IDA:GOC.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   T2FB_HUMAN              Reviewed;         249 AA.
AC   P13984; A6NNS5; Q5W0H3;
DE   RecName: Full=General transcription factor IIF subunit 2;
DE            EC=3.6.4.12;
DE   AltName: Full=ATP-dependent helicase GTF2F2;
DE   AltName: Full=General transcription factor IIF 30 kDa subunit;
DE   AltName: Full=Transcription initiation factor IIF subunit beta;
DE            Short=TFIIF-beta;
DE   AltName: Full=Transcription initiation factor RAP30;
GN   Name=GTF2F2; Synonyms=RAP30;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   T2H2L_HUMAN             Reviewed;         395 AA.
AC   Q6P1K8; A6NED9; A8K8J6; B2RCU4; B7ZW39;
DE   RecName: Full=General transcription factor IIH subunit 2-like protein;
DE   AltName: Full=General transcription factor IIH polypeptide 2-like protein;
GN   Name=GTF2H2C;
GN   and
GN   Name=GTF2H2D;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   T2R10_HUMAN             Reviewed;         307 AA.
AC   Q9NYW0; Q3MIM9; Q6NTD9;
DE   RecName: Full=Taste receptor type 2 member 10;
DE            Short=T2R10;
DE   AltName: Full=Taste receptor family B member 2;
DE            Short=TRB2;
GN   Name=TAS2R10;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
//
ID   T2R13_HUMAN             Reviewed;         303 AA.
AC   Q9NYV9; Q4G0I5; Q502V8; Q645X2;
DE   RecName: Full=Taste receptor type 2 member 13;
DE            Short=T2R13;
DE   AltName: Full=Taste receptor family B member 3;
DE            Short=TRB3;
GN   Name=TAS2R13;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
//
ID   T2R14_HUMAN             Reviewed;         317 AA.
AC   Q9NYV8; Q645X3;
DE   RecName: Full=Taste receptor type 2 member 14;
DE            Short=T2R14;
DE   AltName: Full=Taste receptor family B member 1;
DE            Short=TRB1;
GN   Name=TAS2R14;
DR   GO; GO:0033038; F:bitter taste receptor activity; IDA:HGNC.
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IC:HGNC.
//
ID   T2R16_HUMAN             Reviewed;         291 AA.
AC   Q9NYV7; A4D0X2; Q502V3; Q549U8; Q645W1;
DE   RecName: Full=Taste receptor type 2 member 16;
DE            Short=T2R16;
GN   Name=TAS2R16;
DR   GO; GO:0033038; F:bitter taste receptor activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IC:HGNC.
//
ID   T2R19_HUMAN             Reviewed;         299 AA.
AC   P59542; Q3MIJ4; Q645X8;
DE   RecName: Full=Taste receptor type 2 member 19;
DE   AltName: Full=Taste receptor type 2 member 23;
DE   AltName: Full=Taste receptor type 2 member 48;
DE            Short=T2R48;
GN   Name=TAS2R19; Synonyms=TAS2R23, TAS2R48;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R20_HUMAN             Reviewed;         309 AA.
AC   P59543; P59549; Q2HIZ4; Q496D8; Q645X9;
DE   RecName: Full=Taste receptor type 2 member 20;
DE   AltName: Full=Taste receptor type 2 member 49;
DE            Short=T2R49;
DE   AltName: Full=Taste receptor type 2 member 56;
DE            Short=T2R56;
GN   Name=TAS2R20; Synonyms=TAS2R49;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R30_HUMAN             Reviewed;         319 AA.
AC   P59541; Q645X7;
DE   RecName: Full=Taste receptor type 2 member 30;
DE            Short=T2R30;
DE   AltName: Full=Taste receptor type 2 member 47;
DE            Short=T2R47;
GN   Name=TAS2R30; Synonyms=TAS2R47;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R31_HUMAN             Reviewed;         309 AA.
AC   P59538; P59547; Q17R84; Q645X5;
DE   RecName: Full=Taste receptor type 2 member 31;
DE            Short=T2R31;
DE   AltName: Full=Taste receptor type 2 member 44;
DE            Short=T2R44;
DE   AltName: Full=Taste receptor type 2 member 53;
DE            Short=T2R53;
GN   Name=TAS2R31; Synonyms=TAS2R44;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R38_HUMAN             Reviewed;         333 AA.
AC   P59533; A4D1U6; P59552; Q2M3E8; Q645W3; Q86UK3;
DE   RecName: Full=Taste receptor type 2 member 38;
DE            Short=T2R38;
DE   AltName: Full=PTC bitter taste receptor;
DE   AltName: Full=Taste receptor type 2 member 61;
DE            Short=T2R61;
GN   Name=TAS2R38; Synonyms=PTC;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R39_HUMAN             Reviewed;         338 AA.
AC   P59534; A4FUI7; Q3ZCN6; Q645W4;
DE   RecName: Full=Taste receptor type 2 member 39;
DE            Short=T2R39;
DE   AltName: Full=Taste receptor type 2 member 57;
DE            Short=T2R57;
GN   Name=TAS2R39;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R40_HUMAN             Reviewed;         323 AA.
AC   P59535; A4D2I2; Q645W6;
DE   RecName: Full=Taste receptor type 2 member 40;
DE            Short=T2R40;
DE   AltName: Full=G-protein coupled receptor 60;
DE   AltName: Full=Taste receptor type 2 member 58;
DE            Short=T2R58;
GN   Name=TAS2R40; Synonyms=GPR60;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R41_HUMAN             Reviewed;         307 AA.
AC   P59536; P59550; Q495I2; Q50KJ5; Q50KJ6; Q50KJ7; Q645W7;
DE   RecName: Full=Taste receptor type 2 member 41;
DE            Short=T2R41;
DE   AltName: Full=Taste receptor type 2 member 59;
DE            Short=T2R59;
GN   Name=TAS2R41;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R42_HUMAN             Reviewed;         314 AA.
AC   Q7RTR8; A2RRP4; Q645X0;
DE   RecName: Full=Taste receptor type 2 member 42;
DE            Short=T2R42;
DE   AltName: Full=Taste receptor type 2 member 55;
DE            Short=T2R55;
GN   Name=TAS2R42; Synonyms=TAS2R55;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R43_HUMAN             Reviewed;         309 AA.
AC   P59537; P59546; Q645X4;
DE   RecName: Full=Taste receptor type 2 member 43;
DE            Short=T2R43;
DE   AltName: Full=Taste receptor type 2 member 52;
DE            Short=T2R52;
GN   Name=TAS2R43;
DR   GO; GO:0033038; F:bitter taste receptor activity; IDA:HGNC.
DR   GO; GO:0008527; F:taste receptor activity; IDA:HGNC.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IC:HGNC.
//
ID   T2R45_HUMAN             Reviewed;         299 AA.
AC   P59539;
DE   RecName: Full=Taste receptor type 2 member 45;
DE            Short=T2R45;
DE   AltName: Full=G-protein coupled receptor 59;
GN   Name=TAS2R45; Synonyms=GPR59;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R46_HUMAN             Reviewed;         309 AA.
AC   P59540; P59548; Q645X6;
DE   RecName: Full=Taste receptor type 2 member 46;
DE            Short=T2R46;
DE   AltName: Full=Taste receptor type 2 member 54;
DE            Short=T2R54;
GN   Name=TAS2R46;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R50_HUMAN             Reviewed;         299 AA.
AC   P59544; P59545; Q2M255; Q645Y0;
DE   RecName: Full=Taste receptor type 2 member 50;
DE            Short=T2R50;
DE   AltName: Full=Taste receptor type 2 member 51;
DE            Short=T2R51;
GN   Name=TAS2R50;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:UniProtKB-KW.
//
ID   T2R60_HUMAN             Reviewed;         318 AA.
AC   P59551; A4D2G8; Q645W8; Q7RTR7;
DE   RecName: Full=Taste receptor type 2 member 60;
DE            Short=T2R60;
DE   AltName: Full=Taste receptor type 2 member 56;
DE            Short=T2R56;
GN   Name=TAS2R60;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; NAS:UniProtKB.
DR   GO; GO:0050913; P:sensory perception of bitter taste; NAS:UniProtKB.
//
ID   T3HPD_HUMAN             Reviewed;         354 AA.
AC   Q96EM0; Q96LJ5;
DE   RecName: Full=Trans-L-3-hydroxyproline dehydratase;
DE            EC=4.2.1.77;
DE   AltName: Full=Trans-3-hydroxy-l-proline dehydratase;
GN   Name=L3HYPDH; Synonyms=C14orf149;
DR   GO; GO:0016836; F:hydro-lyase activity; IDA:UniProtKB.
DR   GO; GO:0050346; F:trans-L-3-hydroxyproline dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
//
ID   T3JAM_HUMAN             Reviewed;         551 AA.
AC   Q9Y228; A1L464; A6NIU9; Q2YDB5; Q4VY06; Q7Z706;
DE   RecName: Full=TRAF3-interacting JNK-activating modulator;
DE   AltName: Full=TRAF3-interacting protein 3;
GN   Name=TRAF3IP3; Synonyms=T3JAM;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   T49D1_HUMAN             Reviewed;         452 AA.
AC   C9J1S8; I1YAP9;
DE   RecName: Full=Tripartite motif-containing protein 49D1;
DE   AltName: Full=Tripartite motif-containing protein 49-like protein;
DE   AltName: Full=Tripartite motif-containing protein 49D2 pseudogene;
GN   Name=TRIM49D1; Synonyms=TRIM49L, TRIM49L1;
GN   and
GN   Name=TRIM49D2P;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   T4S18_HUMAN             Reviewed;         201 AA.
AC   Q96CE8; B2R8K0; D3DNH5;
DE   RecName: Full=Transmembrane 4 L6 family member 18;
GN   Name=TM4SF18;
//
ID   T4S19_HUMAN             Reviewed;         209 AA.
AC   Q96DZ7; B2RV20; E9PH22; Q336K7;
DE   RecName: Full=Transmembrane 4 L6 family member 19;
DE   AltName: Full=Osteoclast maturation-associated gene 4 protein;
DE   AltName: Full=Tetraspan membrane protein OCTM4;
GN   Name=TM4SF19; Synonyms=OCTM4;
//
ID   T4S1_HUMAN              Reviewed;         202 AA.
AC   P30408; Q6IB51;
DE   RecName: Full=Transmembrane 4 L6 family member 1;
DE   AltName: Full=Membrane component chromosome 3 surface marker 1;
DE   AltName: Full=Tumor-associated antigen L6;
GN   Name=TM4SF1; Synonyms=M3S1, TAAL6;
//
ID   T4S20_HUMAN             Reviewed;         229 AA.
AC   Q53R12; B2RP42; Q5U609; Q6UWS1; Q9H5X9;
DE   RecName: Full=Transmembrane 4 L6 family member 20;
GN   Name=TM4SF20; ORFNames=UNQ518/PRO994;
//
ID   T4S4_HUMAN              Reviewed;         202 AA.
AC   P48230; B2RDA4;
DE   RecName: Full=Transmembrane 4 L6 family member 4;
DE   AltName: Full=Intestine and liver tetraspan membrane protein;
DE            Short=IL-TMP;
GN   Name=TM4SF4; Synonyms=ILTMP;
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
//
ID   T4S5_HUMAN              Reviewed;         197 AA.
AC   O14894; Q17RW9; Q6IB79;
DE   RecName: Full=Transmembrane 4 L6 family member 5;
DE   AltName: Full=Tetraspan transmembrane protein L6H;
GN   Name=TM4SF5;
//
ID   T53G1_HUMAN             Reviewed;          90 AA.
AC   Q9Y2A0; D6W5P2; Q52MB0; Q9Y2A1; Q9Y2A2; Q9Y2A3;
DE   RecName: Full=TP53-target gene 1 protein;
DE   AltName: Full=TP53-inducible gene 1 protein;
DE   AltName: Full=Tumor protein p53-activated protein 1;
GN   Name=TP53TG1; Synonyms=P53TG1, TP53AP1;
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; NAS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
//
ID   T53G3_HUMAN             Reviewed;         132 AA.
AC   Q9ULZ0; B2R5K6; Q4KN31; Q9ULY9;
DE   RecName: Full=TP53-target gene 3 protein;
DE   AltName: Full=TP53-inducible gene 3 protein;
GN   Name=TP53TG3; Synonyms=TP53TG3A;
GN   and
GN   Name=TP53TG3B;
GN   and
GN   Name=TP53TG3C;
GN   and
GN   Name=TP53TG3D;
//
ID   T53G5_HUMAN             Reviewed;         290 AA.
AC   Q9Y2B4;
DE   RecName: Full=TP53-target gene 5 protein;
DE   AltName: Full=TP53-inducible gene 5 protein;
GN   Name=TP53TG5; Synonyms=C20orf10;
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
//
ID   T53I1_HUMAN             Reviewed;         240 AA.
AC   Q96A56; B2RCE5; Q969R9;
DE   RecName: Full=Tumor protein p53-inducible nuclear protein 1;
DE   AltName: Full=Stress-induced protein;
DE   AltName: Full=p53-dependent damage-inducible nuclear protein 1;
DE            Short=p53DINP1;
GN   Name=TP53INP1; Synonyms=P53DINP1, SIP;
DR   GO; GO:0016209; F:antioxidant activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0048102; P:autophagic cell death; IMP:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0071447; P:cellular response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0072703; P:cellular response to methyl methanesulfonate; IEA:Ensembl.
DR   GO; GO:0034644; P:cellular response to UV; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   T53I2_HUMAN             Reviewed;         220 AA.
AC   Q8IXH6; A8K8S8; E1P5P6; Q5JX64; Q8IYL5; Q9NU00;
DE   RecName: Full=Tumor protein p53-inducible nuclear protein 2;
DE   AltName: Full=Diabetes and obesity-regulated gene;
DE   AltName: Full=p53-inducible protein U;
DE            Short=PIG-U;
GN   Name=TP53INP2; Synonyms=C20orf110, DOR, PINH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IDA:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   T73AS_HUMAN             Reviewed;         201 AA.
AC   Q9UF72;
DE   RecName: Full=Putative TP73 antisense gene protein 1;
DE   AltName: Full=TP73 antisense RNA 1;
DE   AltName: Full=p53-dependent apoptosis modulator;
DE   Flags: Precursor;
GN   Name=TP73-AS1; Synonyms=KIAA0495, PDAM;
//
ID   TA2R1_HUMAN             Reviewed;         299 AA.
AC   Q9NYW7; Q646G8;
DE   RecName: Full=Taste receptor type 2 member 1;
DE            Short=T2R1;
DE   AltName: Full=Taste receptor family B member 7;
DE            Short=TRB7;
GN   Name=TAS2R1;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0007635; P:chemosensory behavior; TAS:ProtInc.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   TA2R3_HUMAN             Reviewed;         316 AA.
AC   Q9NYW6; A4D1U2; Q645W2; Q75MV6;
DE   RecName: Full=Taste receptor type 2 member 3;
DE            Short=T2R3;
GN   Name=TAS2R3;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
DR   GO; GO:0050909; P:sensory perception of taste; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TA2R4_HUMAN             Reviewed;         299 AA.
AC   Q9NYW5; Q645W5; Q75MV8;
DE   RecName: Full=Taste receptor type 2 member 4;
DE            Short=T2R4;
GN   Name=TAS2R4;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0050909; P:sensory perception of taste; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TA2R5_HUMAN             Reviewed;         299 AA.
AC   Q9NYW4; Q645W0; Q75MV7;
DE   RecName: Full=Taste receptor type 2 member 5;
DE            Short=T2R5;
GN   Name=TAS2R5;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0007635; P:chemosensory behavior; TAS:ProtInc.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
DR   GO; GO:0050909; P:sensory perception of taste; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TA2R7_HUMAN             Reviewed;         318 AA.
AC   Q9NYW3; Q645Y1;
DE   RecName: Full=Taste receptor type 2 member 7;
DE            Short=T2R7;
DE   AltName: Full=Taste receptor family B member 4;
DE            Short=TRB4;
GN   Name=TAS2R7;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
//
ID   TA2R8_HUMAN             Reviewed;         309 AA.
AC   Q9NYW2; Q4KN29; Q645Y2;
DE   RecName: Full=Taste receptor type 2 member 8;
DE            Short=T2R8;
DE   AltName: Full=Taste receptor family B member 5;
DE            Short=TRB5;
GN   Name=TAS2R8;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
//
ID   TA2R9_HUMAN             Reviewed;         312 AA.
AC   Q9NYW1; Q502V7; Q50KT0; Q50KT1; Q645W9;
DE   RecName: Full=Taste receptor type 2 member 9;
DE            Short=T2R9;
DE   AltName: Full=Taste receptor family B member 6;
DE            Short=TRB6;
GN   Name=TAS2R9;
DR   GO; GO:0008527; F:taste receptor activity; TAS:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; TAS:GOC.
//
ID   TA2R_HUMAN              Reviewed;         343 AA.
AC   P21731; O75228; Q6DK52; Q9UCY1; Q9UCY2;
DE   RecName: Full=Thromboxane A2 receptor;
DE            Short=TXA2-R;
DE   AltName: Full=Prostanoid TP receptor;
GN   Name=TBXA2R;
DR   GuidetoPHARMACOLOGY; 346; -.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:Reactome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004961; F:thromboxane A2 receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0045987; P:positive regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0019932; P:second-messenger-mediated signaling; IEA:Ensembl.
DR   GO; GO:0038193; P:thromboxane A2 signaling pathway; TAS:GOC.
//
ID   TA6P_HUMAN              Reviewed;          56 AA.
AC   Q9Y3F1;
DE   RecName: Full=Putative TAP2-associated 6.5 kDa polypeptide;
//
ID   TAAR1_HUMAN             Reviewed;         339 AA.
AC   Q96RJ0; Q2M1W5; Q3MIH8; Q5VUQ1;
DE   RecName: Full=Trace amine-associated receptor 1;
DE            Short=TaR-1;
DE            Short=Trace amine receptor 1;
GN   Name=TAAR1; Synonyms=TA1, TAR1, TRAR1;
DR   GuidetoPHARMACOLOGY; 364; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0001594; F:trace-amine receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
//
ID   TAAR2_HUMAN             Reviewed;         351 AA.
AC   Q9P1P5; Q5QD02; Q6NWS1; Q6NWS2; Q6NWS3;
DE   RecName: Full=Trace amine-associated receptor 2;
DE            Short=TaR-2;
DE            Short=Trace amine receptor 2;
DE   AltName: Full=G-protein coupled receptor 58;
GN   Name=TAAR2; Synonyms=GPR58;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0001594; F:trace-amine receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
//
ID   TAAR3_HUMAN             Reviewed;         343 AA.
AC   Q9P1P4;
DE   RecName: Full=Putative trace amine-associated receptor 3;
DE            Short=TaR-3;
DE            Short=Trace amine receptor 3;
DE            Short=hTaar3;
DE   AltName: Full=G-protein coupled receptor 57;
GN   Name=TAAR3; Synonyms=GPR57;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0001594; F:trace-amine receptor activity; ISS:UniProtKB.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; ISS:UniProtKB.
//
ID   TAAR5_HUMAN             Reviewed;         337 AA.
AC   O14804; D8KZS1; Q2M1V1; Q4VBL1; Q5VUQ3; Q6NTA8;
DE   RecName: Full=Trace amine-associated receptor 5;
DE            Short=TaR-5;
DE            Short=Trace amine receptor 5;
DE            Short=hTaar5;
DE   AltName: Full=Putative neurotransmitter receptor;
GN   Name=TAAR5; Synonyms=PNR;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:1990081; F:trimethylamine receptor activity; IDA:UniProtKB.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   TAAR6_HUMAN             Reviewed;         345 AA.
AC   Q96RI8; Q5VUQ4;
DE   RecName: Full=Trace amine-associated receptor 6;
DE            Short=TaR-6;
DE            Short=Trace amine receptor 6;
DE   AltName: Full=Trace amine receptor 4;
DE            Short=TaR-4;
GN   Name=TAAR6; Synonyms=TA4, TAR4, TRAR4;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0001594; F:trace-amine receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
//
ID   TAAR8_HUMAN             Reviewed;         342 AA.
AC   Q969N4; Q5VUQ0;
DE   RecName: Full=Trace amine-associated receptor 8;
DE            Short=TaR-8;
DE            Short=Trace amine receptor 8;
DE   AltName: Full=G-protein coupled receptor 102;
DE   AltName: Full=Trace amine receptor 5;
DE            Short=TaR-5;
GN   Name=TAAR8; Synonyms=GPR102, TA5, TAR5, TRAR5;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0001594; F:trace-amine receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
//
ID   TAAR9_HUMAN             Reviewed;         348 AA.
AC   Q96RI9;
DE   RecName: Full=Trace amine-associated receptor 9;
DE            Short=TaR-9;
DE            Short=Trace amine receptor 9;
DE   AltName: Full=Trace amine receptor 3;
DE            Short=TaR-3;
GN   Name=TAAR9; Synonyms=TA3, TAR3, TRAR3;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:GDB.
DR   GO; GO:0001594; F:trace-amine receptor activity; IEA:InterPro.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GDB.
//
ID   TAB1_HUMAN              Reviewed;         504 AA.
AC   Q15750; Q2PP09; Q8IZW2;
DE   RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 1;
DE   AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 1;
DE   AltName: Full=TGF-beta-activated kinase 1-binding protein 1;
DE            Short=TAK1-binding protein 1;
GN   Name=TAB1; Synonyms=MAP3K7IP1;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0019209; F:kinase activator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0000185; P:activation of MAPKKK activity; TAS:ProtInc.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TAB2_HUMAN              Reviewed;         693 AA.
AC   Q9NYJ8; B2RCC4; E1P5A0; O94838; Q6I9W8; Q76N06; Q9UFP7;
DE   RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 2;
DE   AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 2;
DE   AltName: Full=TAK1-binding protein 2;
DE            Short=TAB-2;
DE   AltName: Full=TGF-beta-activated kinase 1-binding protein 2;
GN   Name=TAB2; Synonyms=KIAA0733, MAP3K7IP2;
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TAB3_HUMAN              Reviewed;         712 AA.
AC   Q8N5C8; A6NDD9; Q6VQR0;
DE   RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;
DE   AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;
DE   AltName: Full=NF-kappa-B-activating protein 1;
DE   AltName: Full=TAK1-binding protein 3;
DE            Short=TAB-3;
DE   AltName: Full=TGF-beta-activated kinase 1-binding protein 3;
GN   Name=TAB3; Synonyms=MAP3K7IP3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TAC2N_HUMAN             Reviewed;         490 AA.
AC   Q8N9U0;
DE   RecName: Full=Tandem C2 domains nuclear protein;
DE   AltName: Full=Membrane targeting tandem C2 domain-containing protein 1;
DE   AltName: Full=Tandem C2 protein in nucleus;
DE            Short=Tac2-N;
GN   Name=TC2N; Synonyms=C14orf47, MTAC2D1;
//
ID   TACC1_HUMAN             Reviewed;         805 AA.
AC   O75410; B2RBD9; D3DSX6; Q6Y687; Q86YG7; Q8IUJ2; Q8IUJ3; Q8IUJ4;
AC   Q8IZG2; Q8NEY7; Q9UPP9;
DE   RecName: Full=Transforming acidic coiled-coil-containing protein 1;
DE   AltName: Full=Gastric cancer antigen Ga55;
DE   AltName: Full=Taxin-1;
GN   Name=TACC1; Synonyms=KIAA1103;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0022027; P:interkinetic nuclear migration; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IEA:Ensembl.
//
ID   TACC2_HUMAN             Reviewed;        2948 AA.
AC   O95359; Q4VXL0; Q4VXL3; Q4VXL6; Q4VXL7; Q5U5T7; Q86WG6; Q86WG7;
AC   Q8TCK9; Q9BVQ1; Q9NZ41; Q9NZR5;
DE   RecName: Full=Transforming acidic coiled-coil-containing protein 2;
DE   AltName: Full=Anti-Zuai-1;
DE            Short=AZU-1;
GN   Name=TACC2;
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IDA:MGI.
DR   GO; GO:0030953; P:astral microtubule organization; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0022027; P:interkinetic nuclear migration; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IEA:Ensembl.
//
ID   TACC3_HUMAN             Reviewed;         838 AA.
AC   Q9Y6A5; Q3KQS5; Q9UMQ1;
DE   RecName: Full=Transforming acidic coiled-coil-containing protein 3;
DE   AltName: Full=ERIC-1;
GN   Name=TACC3; Synonyms=ERIC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030953; P:astral microtubule organization; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0022027; P:interkinetic nuclear migration; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR   GO; GO:0032886; P:regulation of microtubule-based process; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
//
ID   TACO1_HUMAN             Reviewed;         297 AA.
AC   Q9BSH4; B2RD21; Q8N3N6; Q9UI60;
DE   RecName: Full=Translational activator of cytochrome c oxidase 1;
DE   AltName: Full=Coiled-coil domain-containing protein 44;
DE   AltName: Full=Translational activator of mitochondrially-encoded cytochrome c oxidase I;
GN   Name=TACO1; Synonyms=CCDC44; ORFNames=PRO0477;
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   TACD2_HUMAN             Reviewed;         323 AA.
AC   P09758; Q15658; Q6FG48; Q7Z7Q4; Q96QD2;
DE   RecName: Full=Tumor-associated calcium signal transducer 2;
DE   AltName: Full=Cell surface glycoprotein Trop-2;
DE   AltName: Full=Membrane component chromosome 1 surface marker 1;
DE   AltName: Full=Pancreatic carcinoma marker protein GA733-1;
DE   Flags: Precursor;
GN   Name=TACSTD2; Synonyms=GA733-1, M1S1, TROP2;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0090191; P:negative regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
DR   GO; GO:2000146; P:negative regulation of cell motility; ISS:UniProtKB.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; ISS:UniProtKB.
DR   GO; GO:1900028; P:negative regulation of ruffle assembly; ISS:UniProtKB.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; ISS:UniProtKB.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:2000738; P:positive regulation of stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0050678; P:regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060675; P:ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   TACT_HUMAN              Reviewed;         585 AA.
AC   P40200; Q5JPB3;
DE   RecName: Full=T-cell surface protein tactile;
DE   AltName: Full=Cell surface antigen CD96;
DE   AltName: Full=T cell-activated increased late expression protein;
DE   AltName: CD_antigen=CD96;
DE   Flags: Precursor;
GN   Name=CD96;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
//
ID   TAD2A_HUMAN             Reviewed;         443 AA.
AC   O75478; A8MVD0; B3KMU9; Q9BVJ0; Q9UCW2; Q9UP49;
DE   RecName: Full=Transcriptional adapter 2-alpha;
DE   AltName: Full=Transcriptional adapter 2-like;
DE            Short=ADA2-like protein;
GN   Name=TADA2A; Synonyms=TADA2L; ORFNames=KL04P;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0031063; P:regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
DR   GO; GO:0090043; P:regulation of tubulin deacetylation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TAD2B_HUMAN             Reviewed;         420 AA.
AC   Q86TJ2; A0AUJ8; A4QMR7; B3KSN0; B3KU86; Q6MZG9;
DE   RecName: Full=Transcriptional adapter 2-beta;
DE   AltName: Full=ADA2-like protein beta;
DE            Short=ADA2-beta;
GN   Name=TADA2B; Synonyms=ADA2B;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TADA1_HUMAN             Reviewed;         335 AA.
AC   Q96BN2;
DE   RecName: Full=Transcriptional adapter 1;
DE   AltName: Full=SPT3-associated factor 42;
DE            Short=STAF42;
DE   AltName: Full=Transcriptional adapter 1-like protein;
GN   Name=TADA1; Synonyms=TADA1L;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TADA3_HUMAN             Reviewed;         432 AA.
AC   O75528; Q6FI83; Q9UFS2;
DE   RecName: Full=Transcriptional adapter 3;
DE   AltName: Full=ADA3 homolog;
DE            Short=hADA3;
DE   AltName: Full=STAF54;
DE   AltName: Full=Transcriptional adapter 3-like;
DE            Short=ADA3-like protein;
GN   Name=TADA3; Synonyms=ADA3, TADA3L;
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0031063; P:regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0031647; P:regulation of protein stability; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0090043; P:regulation of tubulin deacetylation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TADBP_HUMAN             Reviewed;         414 AA.
AC   Q13148; A4GUK4; A4GUK5; A4GUK6; B2R629; E2PU12; Q53H27; Q6FI92;
AC   Q96DJ0;
DE   RecName: Full=TAR DNA-binding protein 43;
DE            Short=TDP-43;
GN   Name=TARDBP; Synonyms=TDP43;
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:BHF-UCL.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:BHF-UCL.
DR   GO; GO:0008380; P:RNA splicing; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TAF10_HUMAN             Reviewed;         218 AA.
AC   Q12962; O00703; Q13175; Q6FH13;
DE   RecName: Full=Transcription initiation factor TFIID subunit 10;
DE   AltName: Full=STAF28;
DE   AltName: Full=Transcription initiation factor TFIID 30 kDa subunit;
DE            Short=TAF(II)30;
DE            Short=TAFII-30;
DE            Short=TAFII30;
GN   Name=TAF10; Synonyms=TAF2A, TAF2H, TAFII30;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070063; F:RNA polymerase binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF11_HUMAN             Reviewed;         211 AA.
AC   Q15544; B2R8R3; B4DY18; Q9UHS0;
DE   RecName: Full=Transcription initiation factor TFIID subunit 11;
DE   AltName: Full=TFIID subunit p30-beta;
DE   AltName: Full=Transcription initiation factor TFIID 28 kDa subunit;
DE            Short=TAF(II)28;
DE            Short=TAFII-28;
DE            Short=TAFII28;
GN   Name=TAF11; Synonyms=TAF2I; ORFNames=PRO2134;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF12_HUMAN             Reviewed;         161 AA.
AC   Q16514; D3DPM5; Q15775; Q5T077;
DE   RecName: Full=Transcription initiation factor TFIID subunit 12;
DE   AltName: Full=Transcription initiation factor TFIID 20/15 kDa subunits;
DE            Short=TAFII-20/TAFII-15;
DE            Short=TAFII20/TAFII15;
GN   Name=TAF12; Synonyms=TAF15, TAF2J, TAFII20;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IDA:GOC.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF13_HUMAN             Reviewed;         124 AA.
AC   Q15543; B2R5E5; Q5TYV6;
DE   RecName: Full=Transcription initiation factor TFIID subunit 13;
DE   AltName: Full=Transcription initiation factor TFIID 18 kDa subunit;
DE            Short=TAF(II)18;
DE            Short=TAFII-18;
DE            Short=TAFII18;
GN   Name=TAF13; Synonyms=TAF2K, TAFII18;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF1A_HUMAN             Reviewed;         450 AA.
AC   Q15573; B2RDZ8; D3DTB7; Q9NWA1;
DE   RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit A;
DE   AltName: Full=RNA polymerase I-specific TBP-associated factor 48 kDa;
DE            Short=TAFI48;
DE   AltName: Full=TATA box-binding protein-associated factor 1A;
DE            Short=TBP-associated factor 1A;
DE   AltName: Full=Transcription factor SL1;
DE   AltName: Full=Transcription initiation factor SL1/TIF-IB subunit A;
GN   Name=TAF1A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   TAF1B_HUMAN             Reviewed;         588 AA.
AC   Q53T94; B4DI42; F8WD72; Q15574; Q8WVC3;
DE   RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit B;
DE   AltName: Full=RNA polymerase I-specific TBP-associated factor 63 kDa;
DE            Short=TAFI63;
DE   AltName: Full=TATA box-binding protein-associated factor 1B;
DE            Short=TBP-associated factor 1B;
DE   AltName: Full=Transcription initiation factor SL1/TIF-IB subunit B;
GN   Name=TAF1B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001164; F:RNA polymerase I CORE element sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001187; F:RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0017025; F:TBP-class protein binding; TAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001189; P:RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript; IDA:UniProtKB.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
//
ID   TAF1C_HUMAN             Reviewed;         869 AA.
AC   Q15572; B7Z5K5; B7Z5S4; B7Z908; B7Z9L7; Q59F67; Q8N6V3;
DE   RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C;
DE   AltName: Full=RNA polymerase I-specific TBP-associated factor 110 kDa;
DE            Short=TAFI110;
DE   AltName: Full=TATA box-binding protein-associated factor 1C;
DE            Short=TBP-associated factor 1C;
DE   AltName: Full=Transcription initiation factor SL1/TIF-IB subunit C;
GN   Name=TAF1C;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   TAF1D_HUMAN             Reviewed;         278 AA.
AC   Q9H5J8; Q6I9Y6;
DE   RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit D;
DE   AltName: Full=RNA polymerase I-specific TBP-associated factor 41 kDa;
DE            Short=TAFI41;
DE   AltName: Full=TATA box-binding protein-associated factor 1D;
DE            Short=TBP-associated factor 1D;
DE   AltName: Full=Transcription initiation factor SL1/TIF-IB subunit D;
GN   Name=TAF1D; Synonyms=JOSD3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   TAF1L_HUMAN             Reviewed;        1826 AA.
AC   Q8IZX4; Q0VG57;
DE   RecName: Full=Transcription initiation factor TFIID subunit 1-like;
DE   AltName: Full=TAF(II)210;
DE   AltName: Full=TBP-associated factor 1-like;
DE   AltName: Full=TBP-associated factor 210 kDa;
DE   AltName: Full=Transcription initiation factor TFIID 210 kDa subunit;
GN   Name=TAF1L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0017025; F:TBP-class protein binding; IPI:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0016573; P:histone acetylation; ISS:GOC.
DR   GO; GO:0007140; P:male meiosis; IEP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:GOC.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   TAF1_HUMAN              Reviewed;        1872 AA.
AC   P21675; A5CVC8; A5CVC9; A5CVD0; A5CVD1; B1Q2X3; Q59FZ3; Q6IUZ1;
AC   Q70Q86; Q70Q87; Q70T00; Q70T01; Q70T02; Q70T03;
DE   RecName: Full=Transcription initiation factor TFIID subunit 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Cell cycle gene 1 protein;
DE   AltName: Full=TBP-associated factor 250 kDa;
DE            Short=p250;
DE   AltName: Full=Transcription initiation factor TFIID 250 kDa subunit;
DE            Short=TAF(II)250;
DE            Short=TAFII-250;
DE            Short=TAFII250;
GN   Name=TAF1; Synonyms=BA2R, CCG1, CCGS, TAF2A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:BHF-UCL.
DR   GO; GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0017025; F:TBP-class protein binding; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IC:BHF-UCL.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; ISS:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; IDA:GOC.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.
DR   GO; GO:0000117; P:regulation of transcription involved in G2/M transition of mitotic cell cycle; ISS:BHF-UCL.
DR   GO; GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; ISS:BHF-UCL.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF2_HUMAN              Reviewed;        1199 AA.
AC   Q6P1X5; B2RE82; O43487; O43604; O60668; Q86WW7; Q8IWK4;
DE   RecName: Full=Transcription initiation factor TFIID subunit 2;
DE   AltName: Full=150 kDa cofactor of initiator function;
DE   AltName: Full=RNA polymerase II TBP-associated factor subunit B;
DE   AltName: Full=TBP-associated factor 150 kDa;
DE   AltName: Full=Transcription initiation factor TFIID 150 kDa subunit;
DE            Short=TAF(II)150;
DE            Short=TAFII-150;
DE            Short=TAFII150;
GN   Name=TAF2; Synonyms=CIF150, TAF2B;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   TAF3_HUMAN              Reviewed;         929 AA.
AC   Q5VWG9; Q05DA0; Q6GMS5; Q6P6B5; Q86VY6; Q9BQS9; Q9UFI8;
DE   RecName: Full=Transcription initiation factor TFIID subunit 3;
DE   AltName: Full=140 kDa TATA box-binding protein-associated factor;
DE   AltName: Full=TBP-associated factor 3;
DE   AltName: Full=Transcription initiation factor TFIID 140 kDa subunit;
DE            Short=TAF(II)140;
DE            Short=TAF140;
DE            Short=TAFII-140;
DE            Short=TAFII140;
GN   Name=TAF3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:HGNC.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TAF5L_HUMAN             Reviewed;         589 AA.
AC   O75529; Q5TDI5; Q5TDI6; Q8IW31;
DE   RecName: Full=TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L;
DE   AltName: Full=PCAF-associated factor 65 beta;
DE            Short=PAF65-beta;
GN   Name=TAF5L; Synonyms=PAF65B;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TAF4B_HUMAN             Reviewed;         862 AA.
AC   Q92750; Q29YA4; Q29YA5;
DE   RecName: Full=Transcription initiation factor TFIID subunit 4B;
DE   AltName: Full=Transcription initiation factor TFIID 105 kDa subunit;
DE            Short=TAF(II)105;
DE            Short=TAFII-105;
DE            Short=TAFII105;
GN   Name=TAF4B; Synonyms=TAF2C2, TAFII105;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF4_HUMAN              Reviewed;        1085 AA.
AC   O00268; A6NGD9; Q5TBP6; Q99721; Q9BR40; Q9BX42;
DE   RecName: Full=Transcription initiation factor TFIID subunit 4;
DE   AltName: Full=RNA polymerase II TBP-associated factor subunit C;
DE   AltName: Full=TBP-associated factor 4;
DE   AltName: Full=Transcription initiation factor TFIID 130 kDa subunit;
DE            Short=TAF(II)130;
DE            Short=TAFII-130;
DE            Short=TAFII130;
DE   AltName: Full=Transcription initiation factor TFIID 135 kDa subunit;
DE            Short=TAF(II)135;
DE            Short=TAFII-135;
DE            Short=TAFII135;
GN   Name=TAF4; Synonyms=TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF5_HUMAN              Reviewed;         800 AA.
AC   Q15542; A8K5B4; B2RMR0; B7ZKJ6; Q53EM4; Q5SYD5; Q86UZ7; Q9Y4K5;
DE   RecName: Full=Transcription initiation factor TFIID subunit 5;
DE   AltName: Full=Transcription initiation factor TFIID 100 kDa subunit;
DE            Short=TAF(II)100;
DE            Short=TAFII-100;
DE            Short=TAFII100;
GN   Name=TAF5; Synonyms=TAF2D;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IC:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; IDA:GOC.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF6L_HUMAN             Reviewed;         622 AA.
AC   Q9Y6J9; B2RAT0; Q96HA6;
DE   RecName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L;
DE   AltName: Full=PCAF-associated factor 65-alpha;
DE            Short=PAF65-alpha;
GN   Name=TAF6L; Synonyms=PAF65A;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006338; P:chromatin remodeling; TAS:ProtInc.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TAF6_HUMAN              Reviewed;         677 AA.
AC   P49848; A4D2B2; A4D2B3; B4DT11; D6W5U2; Q6AI29;
DE   RecName: Full=Transcription initiation factor TFIID subunit 6;
DE   AltName: Full=RNA polymerase II TBP-associated factor subunit E;
DE   AltName: Full=Transcription initiation factor TFIID 70 kDa subunit;
DE            Short=TAF(II)70;
DE            Short=TAFII-70;
DE            Short=TAFII70;
DE   AltName: Full=Transcription initiation factor TFIID 80 kDa subunit;
DE            Short=TAF(II)80;
DE            Short=TAFII-80;
DE            Short=TAFII80;
GN   Name=TAF6; Synonyms=TAF2E, TAFII70;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:GOC.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; NAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAF7L_HUMAN             Reviewed;         462 AA.
AC   Q5H9L4; Q5H9L6; Q86XI4; Q9BXU5; Q9H5R0;
DE   RecName: Full=Transcription initiation factor TFIID subunit 7-like;
DE   AltName: Full=Cancer/testis antigen 40;
DE            Short=CT40;
DE   AltName: Full=RNA polymerase II TBP-associated factor subunit Q;
DE   AltName: Full=TATA box-binding protein-associated factor 50 kDa;
DE   AltName: Full=Transcription initiation factor TFIID 50 kDa subunit;
GN   Name=TAF7L; Synonyms=TAF2Q;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro.
//
ID   TAF7_HUMAN              Reviewed;         349 AA.
AC   Q15545; B2RBV9; Q13036;
DE   RecName: Full=Transcription initiation factor TFIID subunit 7;
DE   AltName: Full=RNA polymerase II TBP-associated factor subunit F;
DE   AltName: Full=Transcription initiation factor TFIID 55 kDa subunit;
DE            Short=TAF(II)55;
DE            Short=TAFII-55;
DE            Short=TAFII55;
GN   Name=TAF7; Synonyms=TAF2F, TAFII55;
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; IPI:UniProtKB.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0030520; P:intracellular estrogen receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000296; P:spermine transport; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   TAF8_HUMAN              Reviewed;         310 AA.
AC   Q7Z7C8; Q5T0K1; Q8N4R9; Q96M52;
DE   RecName: Full=Transcription initiation factor TFIID subunit 8;
DE   AltName: Full=Protein taube nuss;
DE   AltName: Full=TBP-associated factor 43 kDa;
DE   AltName: Full=TBP-associated factor 8;
DE   AltName: Full=Transcription initiation factor TFIID 43 kDa subunit;
DE            Short=TAFII-43;
DE            Short=TAFII43;
DE            Short=hTAFII43;
GN   Name=TAF8; Synonyms=TAFII43, TBN;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0001833; P:inner cell mass cell proliferation; IEA:Ensembl.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:HGNC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0045598; P:regulation of fat cell differentiation; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TAF9B_HUMAN             Reviewed;         251 AA.
AC   Q9HBM6; B2RUZ9; Q9Y2S3;
DE   RecName: Full=Transcription initiation factor TFIID subunit 9B;
DE   AltName: Full=Neuronal cell death-related protein 7;
DE            Short=DN-7;
DE   AltName: Full=Transcription initiation factor TFIID subunit 9-like;
DE   AltName: Full=Transcription-associated factor TAFII31L;
GN   Name=TAF9B; Synonyms=TAF9L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IC:BHF-UCL.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IC:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0012501; P:programmed cell death; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
//
ID   TAF9_HUMAN              Reviewed;         264 AA.
AC   Q16594; D3DWA3; Q5U0D1; Q9BTS1;
DE   RecName: Full=Transcription initiation factor TFIID subunit 9;
DE   AltName: Full=RNA polymerase II TBP-associated factor subunit G;
DE   AltName: Full=STAF31/32;
DE   AltName: Full=Transcription initiation factor TFIID 31 kDa subunit;
DE            Short=TAFII-31;
DE            Short=TAFII31;
DE   AltName: Full=Transcription initiation factor TFIID 32 kDa subunit;
DE            Short=TAFII-32;
DE            Short=TAFII32;
GN   Name=TAF9; Synonyms=TAF2G, TAFII31;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IC:BHF-UCL.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IC:BHF-UCL.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0060760; P:positive regulation of response to cytokine stimulus; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TAGAP_HUMAN             Reviewed;         731 AA.
AC   Q8N103; Q2NKM8; Q8NI40; Q96KZ2; Q96QA2;
DE   RecName: Full=T-cell activation Rho GTPase-activating protein;
DE   AltName: Full=T-cell activation GTPase-activating protein;
GN   Name=TAGAP; Synonyms=TAGAP1; ORFNames=FKSG15;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   TAGL2_HUMAN             Reviewed;         199 AA.
AC   P37802; E9KL39; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0;
DE   RecName: Full=Transgelin-2;
DE   AltName: Full=Epididymis tissue protein Li 7e;
DE   AltName: Full=SM22-alpha homolog;
GN   Name=TAGLN2; Synonyms=KIAA0120; ORFNames=CDABP0035;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProt.
//
ID   TAGL3_HUMAN             Reviewed;         199 AA.
AC   Q9UI15; D3DN64; Q96A74;
DE   RecName: Full=Transgelin-3;
DE   AltName: Full=Neuronal protein 22;
DE            Short=NP22;
DE   AltName: Full=Neuronal protein NP25;
GN   Name=TAGLN3; Synonyms=NP25;
DR   GO; GO:0007417; P:central nervous system development; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   TAGL_HUMAN              Reviewed;         201 AA.
AC   Q01995; O15542;
DE   RecName: Full=Transgelin;
DE   AltName: Full=22 kDa actin-binding protein;
DE   AltName: Full=Protein WS3-10;
DE   AltName: Full=Smooth muscle protein 22-alpha;
DE            Short=SM22-alpha;
GN   Name=TAGLN; Synonyms=SM22, WS3-10;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProt.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
//
ID   TAL1_HUMAN              Reviewed;         331 AA.
AC   P17542; D3DQ24;
DE   RecName: Full=T-cell acute lymphocytic leukemia protein 1;
DE            Short=TAL-1;
DE   AltName: Full=Class A basic helix-loop-helix protein 17;
DE            Short=bHLHa17;
DE   AltName: Full=Stem cell protein;
DE   AltName: Full=T-cell leukemia/lymphoma protein 5;
GN   Name=TAL1; Synonyms=BHLHA17, SCL, TCL5;
DR   GO; GO:0003682; F:chromatin binding; IDA:MGI.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0060018; P:astrocyte fate commitment; IEA:Ensembl.
DR   GO; GO:0030221; P:basophil differentiation; IEP:BHF-UCL.
DR   GO; GO:0045165; P:cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0035162; P:embryonic hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0030218; P:erythrocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:Ensembl.
DR   GO; GO:0060217; P:hemangioblast cell differentiation; IEA:Ensembl.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; ISS:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   GO; GO:0030219; P:megakaryocyte differentiation; IEP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030220; P:platelet formation; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IMP:BHF-UCL.
DR   GO; GO:0045799; P:positive regulation of chromatin assembly or disassembly; IMP:BHF-UCL.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:BHF-UCL.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0060375; P:regulation of mast cell differentiation; IEA:Ensembl.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
//
ID   TAL2_HUMAN              Reviewed;         108 AA.
AC   Q16559; A0AVI7;
DE   RecName: Full=T-cell acute lymphocytic leukemia protein 2;
DE            Short=TAL-2;
DE   AltName: Full=Class A basic helix-loop-helix protein 19;
DE            Short=bHLHa19;
GN   Name=TAL2; Synonyms=BHLHA19;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021794; P:thalamus development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TALAN_HUMAN             Reviewed;         216 AA.
AC   Q70YC4;
DE   RecName: Full=Talanin;
GN   Name=ZNF365; Synonyms=KIAA0844;
//
ID   TALD3_HUMAN             Reviewed;        1533 AA.
AC   Q9BVV6; B4DZB6; E7EWM8; J3KQH9; O60328; Q6NYC6; Q6UV20;
DE   RecName: Full=Protein TALPID3;
GN   Name=KIAA0586; Synonyms=TALPID3;
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   TALDO_HUMAN             Reviewed;         337 AA.
AC   P37837; B2R8M2; O00751; Q8WV32; Q8WZ45;
DE   RecName: Full=Transaldolase;
DE            EC=2.2.1.2;
GN   Name=TALDO1; Synonyms=TAL, TALDO, TALDOR;
DR   GO; GO:0048029; F:monosaccharide binding; IEA:Ensembl.
DR   GO; GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0019682; P:glyceraldehyde-3-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0006098; P:pentose-phosphate shunt; TAS:Reactome.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0005999; P:xylulose biosynthetic process; TAS:Reactome.
//
ID   TAM41_HUMAN             Reviewed;         452 AA.
AC   Q96BW9; B4DIY7;
DE   RecName: Full=Mitochondrial translocator assembly and maintenance protein 41 homolog;
DE            Short=TAM41;
DE   AltName: Full=MMP37-like protein, mitochondrial;
DE   Flags: Precursor;
GN   Name=TAMM41; Synonyms=C3orf31;
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; ISS:UniProtKB.
//
ID   TANC1_HUMAN             Reviewed;        1861 AA.
AC   Q9C0D5; C9JD88; Q49AI8;
DE   RecName: Full=Protein TANC1;
DE   AltName: Full=Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1;
GN   Name=TANC1; Synonyms=KIAA1728;
DR   GO; GO:0097062; P:dendritic spine maintenance; IEA:Ensembl.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0008542; P:visual learning; IEA:Ensembl.
//
ID   TANC2_HUMAN             Reviewed;        1990 AA.
AC   Q9HCD6; Q9HAC3; Q9NW88; Q9NXY9; Q9ULS2;
DE   RecName: Full=Protein TANC2;
DE   AltName: Full=Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2;
GN   Name=TANC2; Synonyms=KIAA1148, KIAA1636;
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
//
ID   TANK_HUMAN              Reviewed;         425 AA.
AC   Q92844; D3DPB5; Q7Z4J6; Q92885;
DE   RecName: Full=TRAF family member-associated NF-kappa-B activator;
DE   AltName: Full=TRAF-interacting protein;
DE            Short=I-TRAF;
GN   Name=TANK; Synonyms=ITRAF, TRAF2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TAOK1_HUMAN             Reviewed;        1001 AA.
AC   Q7L7X3; A2RUT8; B7ZLV6; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6;
DE   RecName: Full=Serine/threonine-protein kinase TAO1;
DE            EC=2.7.11.1;
DE   AltName: Full=Kinase from chicken homolog B;
DE            Short=hKFC-B;
DE   AltName: Full=MARK Kinase;
DE            Short=MARKK;
DE   AltName: Full=Prostate-derived sterile 20-like kinase 2;
DE            Short=PSK-2;
DE            Short=PSK2;
DE            Short=Prostate-derived STE20-like kinase 2;
DE   AltName: Full=Thousand and one amino acid protein kinase 1;
DE            Short=TAOK1;
DE            Short=hTAOK1;
GN   Name=TAOK1; Synonyms=KIAA1361, MAP3K16, MARKK;
DR   GuidetoPHARMACOLOGY; 2233; -.
DR   GO; GO:0005524; F:ATP binding; NAS:HGNC.
DR   GO; GO:0016301; F:kinase activity; NAS:HGNC.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:WormBase.
DR   GO; GO:0004672; F:protein kinase activity; NAS:HGNC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; NAS:HGNC.
DR   GO; GO:0000186; P:activation of MAPKK activity; IBA:GOC.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0097194; P:execution phase of apoptosis; IDA:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IBA:GOC.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:HGNC.
DR   GO; GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
//
ID   TAOK2_HUMAN             Reviewed;        1235 AA.
AC   Q9UL54; A5PKY1; A7MCZ2; B2RN35; B7ZM88; O94957; Q6UW73; Q7LC09;
AC   Q9NSW2;
DE   RecName: Full=Serine/threonine-protein kinase TAO2;
DE            EC=2.7.11.1;
DE   AltName: Full=Kinase from chicken homolog C;
DE            Short=hKFC-C;
DE   AltName: Full=Prostate-derived sterile 20-like kinase 1;
DE            Short=PSK-1;
DE            Short=PSK1;
DE            Short=Prostate-derived STE20-like kinase 1;
DE   AltName: Full=Thousand and one amino acid protein kinase 2;
GN   Name=TAOK2; Synonyms=KIAA0881, MAP3K17, PSK, PSK1;
GN   ORFNames=UNQ2971/PRO7431;
DR   GuidetoPHARMACOLOGY; 2234; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; NAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0006612; P:protein targeting to membrane; NAS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; IDA:UniProtKB.
//
ID   TAOK3_HUMAN             Reviewed;         898 AA.
AC   Q9H2K8; Q658N1; Q8IUM4; Q9HC79; Q9NZM9; Q9UHG7;
DE   RecName: Full=Serine/threonine-protein kinase TAO3;
DE            EC=2.7.11.1;
DE   AltName: Full=Cutaneous T-cell lymphoma-associated antigen HD-CL-09;
DE            Short=CTCL-associated antigen HD-CL-09;
DE   AltName: Full=Dendritic cell-derived protein kinase;
DE   AltName: Full=JNK/SAPK-inhibitory kinase;
DE   AltName: Full=Jun kinase-inhibitory kinase;
DE   AltName: Full=Kinase from chicken homolog A;
DE            Short=hKFC-A;
DE   AltName: Full=Thousand and one amino acid protein 3;
GN   Name=TAOK3; Synonyms=DPK, JIK, KDS, MAP3K18;
DR   GuidetoPHARMACOLOGY; 2235; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004709; F:MAP kinase kinase kinase activity; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0016740; F:transferase activity; IDA:HGNC.
DR   GO; GO:0000186; P:activation of MAPKK activity; IBA:GOC.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IMP:HGNC.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:HGNC.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:GOC.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:HGNC.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:HGNC.
DR   GO; GO:0006468; P:protein phosphorylation; IMP:UniProtKB.
//
ID   TAP1_HUMAN              Reviewed;         808 AA.
AC   Q03518; Q16149; Q96CP4;
DE   RecName: Full=Antigen peptide transporter 1;
DE            Short=APT1;
DE   AltName: Full=ATP-binding cassette sub-family B member 2;
DE   AltName: Full=Peptide supply factor 1;
DE   AltName: Full=Peptide transporter PSF1;
DE            Short=PSF-1;
DE   AltName: Full=Peptide transporter TAP1;
DE   AltName: Full=Peptide transporter involved in antigen processing 1;
DE   AltName: Full=Really interesting new gene 4 protein;
GN   Name=TAP1; Synonyms=ABCB2, PSF1, RING4, Y3;
DR   GO; GO:0043531; F:ADP binding; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042288; F:MHC class I protein binding; IBA:RefGenome.
DR   GO; GO:0023029; F:MHC class Ib protein binding; IPI:UniProt.
DR   GO; GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0015197; F:peptide transporter activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0046978; F:TAP1 binding; ISS:UniProtKB.
DR   GO; GO:0046979; F:TAP2 binding; IPI:UniProtKB.
DR   GO; GO:0046980; F:tapasin binding; IBA:RefGenome.
DR   GO; GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; IMP:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0046967; P:cytosol to ER transport; IMP:UniProtKB.
DR   GO; GO:0006952; P:defense response; IEA:Ensembl.
DR   GO; GO:0019060; P:intracellular transport of viral protein in host cell; IMP:UniProtKB.
DR   GO; GO:0035672; P:oligopeptide transmembrane transport; IBA:GOC.
DR   GO; GO:0015833; P:peptide transport; IMP:UniProtKB.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
//
ID   TAP2_HUMAN              Reviewed;         686 AA.
AC   Q03519; B0V2J8; O95410; Q53FI6; Q5HY71; Q96PT8; Q9UQ83;
DE   RecName: Full=Antigen peptide transporter 2;
DE            Short=APT2;
DE   AltName: Full=ATP-binding cassette sub-family B member 3;
DE   AltName: Full=Peptide supply factor 2;
DE   AltName: Full=Peptide transporter PSF2;
DE            Short=PSF-2;
DE   AltName: Full=Peptide transporter TAP2;
DE   AltName: Full=Peptide transporter involved in antigen processing 2;
DE   AltName: Full=Really interesting new gene 11 protein;
GN   Name=TAP2; Synonyms=ABCB3, PSF2, RING11, Y1;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0042288; F:MHC class I protein binding; IBA:RefGenome.
DR   GO; GO:0023029; F:MHC class Ib protein binding; IPI:UniProt.
DR   GO; GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.
DR   GO; GO:0042605; F:peptide antigen binding; IBA:RefGenome.
DR   GO; GO:0015433; F:peptide antigen-transporting ATPase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046978; F:TAP1 binding; IPI:UniProtKB.
DR   GO; GO:0046979; F:TAP2 binding; IBA:RefGenome.
DR   GO; GO:0046980; F:tapasin binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IDA:MGI.
DR   GO; GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; IDA:UniProtKB.
DR   GO; GO:0002485; P:antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; IBA:RefGenome.
DR   GO; GO:0002489; P:antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; IMP:UniProtKB.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002481; P:antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; IBA:RefGenome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0046967; P:cytosol to ER transport; IMP:UniProtKB.
DR   GO; GO:0019060; P:intracellular transport of viral protein in host cell; IMP:UniProtKB.
DR   GO; GO:0035672; P:oligopeptide transmembrane transport; IBA:GOC.
DR   GO; GO:0046968; P:peptide antigen transport; IDA:UniProtKB.
DR   GO; GO:0015833; P:peptide transport; IBA:RefGenome.
DR   GO; GO:0002591; P:positive regulation of antigen processing and presentation of peptide antigen via MHC class I; IBA:RefGenome.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome.
DR   GO; GO:0055085; P:transmembrane transport; IBA:RefGenome.
//
ID   TAP26_HUMAN             Reviewed;         241 AA.
AC   Q9P031; Q9H2V5; Q9NW62;
DE   RecName: Full=Thyroid transcription factor 1-associated protein 26;
DE            Short=TTF-1-associated protein 26;
DE   AltName: Full=Coiled-coil domain-containing protein 59;
DE   AltName: Full=TTF-1-associated protein BR2;
GN   Name=CCDC59; Synonyms=BR22, TAP26; ORFNames=HSPC128;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TAPT1_HUMAN             Reviewed;         567 AA.
AC   Q6NXT6; Q8N2S3; Q9NZK9;
DE   RecName: Full=Transmembrane anterior posterior transformation protein 1 homolog;
DE   AltName: Full=Cytomegalovirus partial fusion receptor;
GN   Name=TAPT1; Synonyms=CMVFR;
DR   GO; GO:0016520; F:growth hormone-releasing hormone receptor activity; TAS:UniProtKB.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GOC.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
//
ID   TARA_HUMAN              Reviewed;        2365 AA.
AC   Q9H2D6; B1AHD4; B1AHD7; F2Z2W0; F8W6V6; O94797; Q2PZW8; Q2Q3Z9;
AC   Q2Q400; Q5R3M6; Q96DW1; Q9BT77; Q9BTL7; Q9BY98; Q9Y3L4;
DE   RecName: Full=TRIO and F-actin-binding protein;
DE   AltName: Full=Protein Tara;
DE   AltName: Full=Trio-associated repeat on actin;
GN   Name=TRIOBP; Synonyms=KIAA1662, TARA; ORFNames=HRIHFB2122;
DR   GO; GO:0051015; F:actin filament binding; IDA:MGI.
DR   GO; GO:0017049; F:GTP-Rho binding; NAS:UniProtKB.
DR   GO; GO:0045159; F:myosin II binding; NAS:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0030047; P:actin modification; NAS:UniProtKB.
DR   GO; GO:0051016; P:barbed-end actin filament capping; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IDA:MGI.
//
ID   TARB1_HUMAN             Reviewed;        1621 AA.
AC   Q13395; Q9H581;
DE   RecName: Full=Probable methyltransferase TARBP1;
DE            EC=2.1.1.-;
DE   AltName: Full=TAR RNA-binding protein 1;
DE   AltName: Full=TAR RNA-binding protein of 185 kDa;
DE            Short=TRP-185;
GN   Name=TARBP1; Synonyms=TRM3, TRP185;
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   TARM1_HUMAN             Reviewed;         271 AA.
AC   B6A8C7; B4DWY4;
DE   RecName: Full=T-cell-interacting, activating receptor on myeloid cells protein 1;
DE   AltName: Full=OSCAR-like transcript-2 protein;
DE            Short=OLT-2;
DE   Flags: Precursor;
GN   Name=TARM1;
//
ID   TARSH_HUMAN             Reviewed;        1075 AA.
AC   Q7Z7G0; B3KSL4; Q6ZW20; Q6ZW22; Q9C082; Q9UFI6;
DE   RecName: Full=Target of Nesh-SH3;
DE            Short=Tarsh;
DE   AltName: Full=ABI gene family member 3-binding protein;
DE   AltName: Full=Nesh-binding protein;
DE            Short=NeshBP;
DE   Flags: Precursor;
GN   Name=ABI3BP; Synonyms=NESHBP, TARSH;
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   TASP1_HUMAN             Reviewed;         420 AA.
AC   Q9H6P5; Q5TDU9; Q9BQN0; Q9NQ08; Q9NTS6; Q9NXJ2;
DE   RecName: Full=Threonine aspartase 1;
DE            Short=Taspase-1;
DE            EC=3.4.25.-;
DE   Contains:
DE     RecName: Full=Threonine aspartase subunit alpha;
DE   Contains:
DE     RecName: Full=Threonine aspartase subunit beta;
GN   Name=TASP1; Synonyms=C20orf13;
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
//
ID   TATD1_HUMAN             Reviewed;         297 AA.
AC   Q6P1N9; B2R5J0; Q8TD02; Q9BY40;
DE   RecName: Full=Putative deoxyribonuclease TATDN1;
DE            EC=3.1.21.-;
DE   AltName: Full=Hepatocarcinoma high expression protein;
GN   Name=TATDN1; ORFNames=CDA11;
DR   GO; GO:0004536; F:deoxyribonuclease activity; IBA:RefGenome.
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IBA:RefGenome.
//
ID   TATD2_HUMAN             Reviewed;         761 AA.
AC   Q93075; Q3MIL9; Q5BKU0;
DE   RecName: Full=Putative deoxyribonuclease TATDN2;
DE            EC=3.1.21.-;
GN   Name=TATDN2; Synonyms=KIAA0218;
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
//
ID   TATD3_HUMAN             Reviewed;         274 AA.
AC   Q17R31; A6NGS3; B7Z1C1; B7Z978; B7ZLQ6; E9PJE5; E9PNH3; G3V151;
AC   Q4G0L1;
DE   RecName: Full=Putative deoxyribonuclease TATDN3;
DE            EC=3.1.21.-;
GN   Name=TATDN3;
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   TAU_HUMAN               Reviewed;         758 AA.
AC   P10636; P18518; Q14799; Q15549; Q15550; Q15551; Q1RMF6; Q53YB1;
AC   Q5CZI7; Q5XWF0; Q6QT54; Q9UDJ3; Q9UMH0; Q9UQ96;
DE   RecName: Full=Microtubule-associated protein tau;
DE   AltName: Full=Neurofibrillary tangle protein;
DE   AltName: Full=Paired helical filament-tau;
DE            Short=PHF-tau;
GN   Name=MAPT; Synonyms=MAPTL, MTBT1, TAU;
DR   GO; GO:0034185; F:apolipoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0071813; F:lipoprotein particle binding; IPI:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0008088; P:axon cargo transport; IEA:Ensembl.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0048699; P:generation of neurons; NAS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IDA:UniProtKB.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; IEA:Ensembl.
DR   GO; GO:0032387; P:negative regulation of intracellular transport; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0045773; P:positive regulation of axon extension; IDA:UniProtKB.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IGI:MGI.
DR   GO; GO:0031113; P:regulation of microtubule polymerization; NAS:UniProtKB.
DR   GO; GO:0060632; P:regulation of microtubule-based movement; IEA:Ensembl.
//
ID   TAXB1_HUMAN             Reviewed;         789 AA.
AC   Q86VP1; B4DKU7; E7ENV2; O60398; O95770; Q13311; Q9BQG5; Q9UI88;
DE   RecName: Full=Tax1-binding protein 1;
DE   AltName: Full=TRAF6-binding protein;
GN   Name=TAX1BP1; Synonyms=T6BP; ORFNames=PRO0105;
DR   GO; GO:0019900; F:kinase binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
//
ID   TAZ_HUMAN               Reviewed;         292 AA.
AC   Q16635; A3KQT2; D3DWX2; Q5HY43; Q5HY44; Q5HY45; Q5HY48; Q86XQ6;
AC   Q86XQ7; Q86XQ8; Q86XQ9; Q86XR0;
DE   RecName: Full=Tafazzin;
DE   AltName: Full=Protein G4.5;
GN   Name=TAZ; Synonyms=EFE2, G4.5;
DR   GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0048738; P:cardiac muscle tissue development; IMP:HGNC.
DR   GO; GO:0035965; P:cardiolipin acyl-chain remodeling; TAS:Reactome.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0042407; P:cristae formation; IMP:HGNC.
DR   GO; GO:0046474; P:glycerophospholipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IMP:HGNC.
DR   GO; GO:0030097; P:hemopoiesis; IMP:HGNC.
DR   GO; GO:0042775; P:mitochondrial ATP synthesis coupled electron transport; IDA:BHF-UCL.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:HGNC.
DR   GO; GO:0006936; P:muscle contraction; IMP:HGNC.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IMP:HGNC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TB10A_HUMAN             Reviewed;         508 AA.
AC   Q9BXI6; B3KXT8; O76053; Q20WK7; Q543A2;
DE   RecName: Full=TBC1 domain family member 10A;
DE   AltName: Full=EBP50-PDX interactor of 64 kDa;
DE            Short=EPI64 protein;
DE   AltName: Full=Rab27A-GAP-alpha;
GN   Name=TBC1D10A; Synonyms=EPI64, TBC1D10;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030165; F:PDZ domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
//
ID   TB10C_HUMAN             Reviewed;         446 AA.
AC   Q8IV04; G3V1D6;
DE   RecName: Full=Carabin;
DE   AltName: Full=TBC1 domain family member 10C;
GN   Name=TBC1D10C;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TB10B_HUMAN             Reviewed;         808 AA.
AC   Q4KMP7; B9A6L0; Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6;
AC   Q9UFP2;
DE   RecName: Full=TBC1 domain family member 10B;
DE   AltName: Full=Rab27A-GAP-beta;
GN   Name=TBC1D10B; ORFNames=FP2461;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; IDA:UniProtKB.
//
ID   TB15A_HUMAN             Reviewed;          45 AA.
AC   P0CG34; A8K614; Q99406;
DE   RecName: Full=Thymosin beta-15A;
DE   AltName: Full=NB thymosin beta;
DE   AltName: Full=Thymosin-like protein 8;
GN   Name=TMSB15A; Synonyms=TMSL8, TMSNB;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0042989; P:sequestering of actin monomers; IEA:InterPro.
//
ID   TB182_HUMAN             Reviewed;        1729 AA.
AC   Q9C0C2; A7E2F8; Q6PJ35; Q6ZV74;
DE   RecName: Full=182 kDa tankyrase-1-binding protein;
GN   Name=TNKS1BP1; Synonyms=KIAA1741, TAB182;
DR   GO; GO:0030506; F:ankyrin binding; NAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; NAS:UniProtKB.
//
ID   TB15B_HUMAN             Reviewed;          45 AA.
AC   P0CG35; A8K614; Q99406;
DE   RecName: Full=Thymosin beta-15B;
GN   Name=TMSB15B;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0042989; P:sequestering of actin monomers; IEA:InterPro.
//
ID   TB22A_HUMAN             Reviewed;         517 AA.
AC   Q8WUA7; B0QYI2; B0QYI3; B9A6M3; Q5TE47; Q6ZUH2; Q92680; Q9BVD6;
AC   Q9UGG0; Q9UGT2; Q9UGU6; Q9UH25; Q9Y4W5;
DE   RecName: Full=TBC1 domain family member 22A;
GN   Name=TBC1D22A; Synonyms=C22orf4;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TB22B_HUMAN             Reviewed;         505 AA.
AC   Q9NU19; A8KA28; Q32MQ8; Q5VUK9; Q6P4C3; Q7Z6P7; Q9BPV6; Q9BUT5;
AC   Q9NXB6;
DE   RecName: Full=TBC1 domain family member 22B;
GN   Name=TBC1D22B; Synonyms=C6orf197;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBA1A_HUMAN             Reviewed;         451 AA.
AC   Q71U36; A8K0B8; G3V1U9; P04687; P05209;
DE   RecName: Full=Tubulin alpha-1A chain;
DE   AltName: Full=Alpha-tubulin 3;
DE   AltName: Full=Tubulin B-alpha-1;
DE   AltName: Full=Tubulin alpha-3 chain;
GN   Name=TUBA1A; Synonyms=TUBA3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; TAS:BHF-UCL.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0051301; P:cell division; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; TAS:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBA1B_HUMAN             Reviewed;         451 AA.
AC   P68363; P04687; P05209; Q27I68;
DE   RecName: Full=Tubulin alpha-1B chain;
DE   AltName: Full=Alpha-tubulin ubiquitous;
DE   AltName: Full=Tubulin K-alpha-1;
DE   AltName: Full=Tubulin alpha-ubiquitous chain;
GN   Name=TUBA1B;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl.
DR   GO; GO:0005198; F:structural molecule activity; TAS:BHF-UCL.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0051301; P:cell division; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IEA:Ensembl.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007017; P:microtubule-based process; TAS:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBA1C_HUMAN             Reviewed;         449 AA.
AC   Q9BQE3;
DE   RecName: Full=Tubulin alpha-1C chain;
DE   AltName: Full=Alpha-tubulin 6;
DE   AltName: Full=Tubulin alpha-6 chain;
GN   Name=TUBA1C; Synonyms=TUBA6;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; TAS:BHF-UCL.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0051301; P:cell division; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL.
DR   GO; GO:0007017; P:microtubule-based process; TAS:BHF-UCL.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBA3C_HUMAN             Reviewed;         450 AA.
AC   Q13748; A6NJQ0; Q5W099; Q6PEY3; Q96F18;
DE   RecName: Full=Tubulin alpha-3C/D chain;
DE   AltName: Full=Alpha-tubulin 2;
DE   AltName: Full=Alpha-tubulin 3C/D;
DE   AltName: Full=Tubulin alpha-2 chain;
GN   Name=TUBA3C; Synonyms=TUBA2;
GN   and
GN   Name=TUBA3D;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBA3E_HUMAN             Reviewed;         450 AA.
AC   Q6PEY2;
DE   RecName: Full=Tubulin alpha-3E chain;
DE   AltName: Full=Alpha-tubulin 3E;
GN   Name=TUBA3E;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBA4A_HUMAN             Reviewed;         448 AA.
AC   P68366; B3KNQ6; P05215;
DE   RecName: Full=Tubulin alpha-4A chain;
DE   AltName: Full=Alpha-tubulin 1;
DE   AltName: Full=Testis-specific alpha-tubulin;
DE   AltName: Full=Tubulin H2-alpha;
DE   AltName: Full=Tubulin alpha-1 chain;
GN   Name=TUBA4A; Synonyms=TUBA1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBA4B_HUMAN             Reviewed;         241 AA.
AC   Q9H853;
DE   RecName: Full=Putative tubulin-like protein alpha-4B;
DE   AltName: Full=Alpha-tubulin 4B;
GN   Name=TUBA4B; Synonyms=TUBA4;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
//
ID   TBA8_HUMAN              Reviewed;         449 AA.
AC   Q9NY65; B2RCX2; B3KPW9; B4DWG3; Q2M3N4;
DE   RecName: Full=Tubulin alpha-8 chain;
DE   AltName: Full=Alpha-tubulin 8;
DE   AltName: Full=Tubulin alpha chain-like 2;
GN   Name=TUBA8; Synonyms=TUBAL2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBATA_HUMAN             Reviewed;         351 AA.
AC   Q96M53; A4QPA8; B2RPQ2; Q5T4G2;
DE   RecName: Full=Protein TBATA;
DE   AltName: Full=Protein SPATIAL;
DE   AltName: Full=Stromal protein associated with thymii and lymph node homolog;
DE   AltName: Full=Thymus, brain and testes-associated protein;
GN   Name=TBATA; Synonyms=C10orf27, SPATIAL;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TBAL3_HUMAN             Reviewed;         446 AA.
AC   A6NHL2; B4DKL2; Q4QQJ5; Q9H6Z0;
DE   RecName: Full=Tubulin alpha chain-like 3;
GN   Name=TUBAL3;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB1_HUMAN              Reviewed;         451 AA.
AC   Q9H4B7;
DE   RecName: Full=Tubulin beta-1 chain;
GN   Name=TUBB1;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
DR   GO; GO:0051225; P:spindle assembly; IEA:Ensembl.
//
ID   TBB2A_HUMAN             Reviewed;         445 AA.
AC   Q13885; Q6FGZ8; Q8IWR2;
DE   RecName: Full=Tubulin beta-2A chain;
DE   AltName: Full=Tubulin beta class IIa;
GN   Name=TUBB2A; Synonyms=TUBB2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB2B_HUMAN             Reviewed;         445 AA.
AC   Q9BVA1; A8K068;
DE   RecName: Full=Tubulin beta-2B chain;
GN   Name=TUBB2B;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0001764; P:neuron migration; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB3_HUMAN              Reviewed;         450 AA.
AC   Q13509; A8K854; Q9BTZ0; Q9BW10;
DE   RecName: Full=Tubulin beta-3 chain;
DE   AltName: Full=Tubulin beta-4 chain;
DE   AltName: Full=Tubulin beta-III;
GN   Name=TUBB3; Synonyms=TUBB4;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; IMP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB4A_HUMAN             Reviewed;         444 AA.
AC   P04350; B3KQP4; Q969E5;
DE   RecName: Full=Tubulin beta-4A chain;
DE   AltName: Full=Tubulin 5 beta;
DE   AltName: Full=Tubulin beta-4 chain;
GN   Name=TUBB4A; Synonyms=TUBB4, TUBB5;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB4B_HUMAN             Reviewed;         445 AA.
AC   P68371; A2BFA2; P05217;
DE   RecName: Full=Tubulin beta-4B chain;
DE   AltName: Full=Tubulin beta-2 chain;
DE   AltName: Full=Tubulin beta-2C chain;
GN   Name=TUBB4B; Synonyms=TUBB2C;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042288; F:MHC class I protein binding; TAS:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB5_HUMAN              Reviewed;         444 AA.
AC   P07437; P05218; Q8WUC1; Q9CY33;
DE   RecName: Full=Tubulin beta chain;
DE   AltName: Full=Tubulin beta-5 chain;
GN   Name=TUBB; Synonyms=TUBB5; ORFNames=OK/SW-cl.56;
DR   GuidetoPHARMACOLOGY; 2640; -.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl.
DR   GO; GO:0005198; F:structural molecule activity; TAS:BHF-UCL.
DR   GO; GO:0051301; P:cell division; TAS:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0009987; P:cellular process; IDA:DFLAT.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; TAS:BHF-UCL.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; TAS:BHF-UCL.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0042267; P:natural killer cell mediated cytotoxicity; NAS:UniProtKB.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
DR   GO; GO:0051225; P:spindle assembly; IEA:Ensembl.
//
ID   TBB6_HUMAN              Reviewed;         446 AA.
AC   Q9BUF5; B3KM76; Q9HA42;
DE   RecName: Full=Tubulin beta-6 chain;
DE   AltName: Full=Tubulin beta class V;
GN   Name=TUBB6;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB8L_HUMAN             Reviewed;         444 AA.
AC   A6NNZ2;
DE   RecName: Full=Tubulin beta-8 chain-like protein LOC260334;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBB8_HUMAN              Reviewed;         444 AA.
AC   Q3ZCM7; Q5SQX9; Q8WZ78;
DE   RecName: Full=Tubulin beta-8 chain;
GN   Name=TUBB8;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBC12_HUMAN             Reviewed;         775 AA.
AC   O60347; Q5VYA6; Q8WX26; Q8WX59; Q9UG83;
DE   RecName: Full=TBC1 domain family member 12;
GN   Name=TBC1D12; Synonyms=KIAA0608;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC13_HUMAN             Reviewed;         400 AA.
AC   Q9NVG8; A7E2E7; B3KW04; B9EGJ8; Q5T270; Q5T271;
DE   RecName: Full=TBC1 domain family member 13;
GN   Name=TBC1D13;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC14_HUMAN             Reviewed;         693 AA.
AC   Q9P2M4; B9A6L5; D3DVT4; E9PAZ6; Q8IW15; Q8NDK3;
DE   RecName: Full=TBC1 domain family member 14;
GN   Name=TBC1D14; Synonyms=KIAA1322;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:BHF-UCL.
DR   GO; GO:2000785; P:regulation of autophagic vacuole assembly; IMP:BHF-UCL.
//
ID   TBC15_HUMAN             Reviewed;         691 AA.
AC   Q8TC07; B4DMT9; B9A6L6; J3KNI9; Q9HA83;
DE   RecName: Full=TBC1 domain family member 15;
DE   AltName: Full=GTPase-activating protein RAB7;
DE            Short=GAP for RAB7;
DE            Short=Rab7-GAP;
GN   Name=TBC1D15;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005097; F:Rab GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0032313; P:regulation of Rab GTPase activity; ISS:UniProtKB.
//
ID   TBC17_HUMAN             Reviewed;         648 AA.
AC   Q9HA65; B4DT12; B9A6L8; F5H1W7;
DE   RecName: Full=TBC1 domain family member 17;
GN   Name=TBC1D17;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC16_HUMAN             Reviewed;         767 AA.
AC   Q8TBP0; B9A6L7; Q8N3Z4;
DE   RecName: Full=TBC1 domain family member 16;
GN   Name=TBC1D16;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC20_HUMAN             Reviewed;         403 AA.
AC   Q96BZ9; A8K6I3; B9A6M1; Q5JWQ7; Q6ZSY8; Q96NE1; Q9BYM7; Q9H140;
DE   RecName: Full=TBC1 domain family member 20;
GN   Name=TBC1D20; Synonyms=C20orf140;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TBC19_HUMAN             Reviewed;         526 AA.
AC   Q8N5T2; B9A6M0; Q9NUX1;
DE   RecName: Full=TBC1 domain family member 19;
GN   Name=TBC1D19;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC21_HUMAN             Reviewed;         336 AA.
AC   Q8IYX1; B9A6M2;
DE   RecName: Full=TBC1 domain family member 21;
GN   Name=TBC1D21;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC23_HUMAN             Reviewed;         699 AA.
AC   Q9NUY8; B9A6M5; Q8TCN8; Q8WUB7; Q96D90; Q9NV75;
DE   RecName: Full=TBC1 domain family member 23;
DE   AltName: Full=HCV non-structural protein 4A-transactivated protein 1;
GN   Name=TBC1D23; Synonyms=NS4ATP1;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0032680; P:regulation of tumor necrosis factor production; IEA:Ensembl.
//
ID   TBC24_HUMAN             Reviewed;         559 AA.
AC   Q9ULP9; A0JNW3; B9A6M6; Q2KJ08;
DE   RecName: Full=TBC1 domain family member 24;
GN   Name=TBC1D24; Synonyms=KIAA1171;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
//
ID   TBC25_HUMAN             Reviewed;         688 AA.
AC   Q3MII6; Q08AN9; Q3MII4; Q8TAR9;
DE   RecName: Full=TBC1 domain family member 25;
GN   Name=TBC1D25; Synonyms=OATL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:1901096; P:regulation of autophagic vacuole maturation; IMP:UniProtKB.
//
ID   TBC26_HUMAN             Reviewed;         250 AA.
AC   Q86UD7; A8K929; Q4G172;
DE   RecName: Full=TBC1 domain family member 26;
GN   Name=TBC1D26;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC28_HUMAN             Reviewed;         210 AA.
AC   Q2M2D7; Q2M2E1;
DE   RecName: Full=TBC1 domain family member 28;
GN   Name=TBC1D28;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC29_HUMAN             Reviewed;         150 AA.
AC   Q9UFV1;
DE   RecName: Full=Putative TBC1 domain family member 29;
GN   Name=TBC1D29;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC31_HUMAN             Reviewed;        1066 AA.
AC   Q96DN5; B7ZL19; Q2M2J9; Q3MIR6; Q8TBP9;
DE   RecName: Full=TBC1 domain family member 31;
DE   AltName: Full=WD repeat-containing protein 67;
GN   Name=TBC1D31; Synonyms=WDR67;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC30_HUMAN             Reviewed;         924 AA.
AC   Q9Y2I9; B3KP01; B9A6M9; E7EMW4; F5GYJ9;
DE   RecName: Full=TBC1 domain family member 30;
GN   Name=TBC1D30; Synonyms=KIAA0984;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC3A_HUMAN             Reviewed;         549 AA.
AC   Q8IZP1; A6NGX2; A8K007; Q9H0B9; Q9UDD4;
DE   RecName: Full=TBC1 domain family member 3;
DE   AltName: Full=Prostate cancer gene 17 protein;
DE   AltName: Full=Protein TRE17-alpha;
DE   AltName: Full=Rab GTPase-activating protein PRC17;
GN   Name=TBC1D3; Synonyms=PRC17, TBC1D3A;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC3B_HUMAN             Reviewed;         549 AA.
AC   A6NDS4; A8K892;
DE   RecName: Full=TBC1 domain family member 3B;
GN   Name=TBC1D3B; Synonyms=TBC1D3I;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC3F_HUMAN             Reviewed;         549 AA.
AC   A6NER0;
DE   RecName: Full=TBC1 domain family member 3F;
GN   Name=TBC1D3F; Synonyms=TBC1D3E;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC3C_HUMAN             Reviewed;         549 AA.
AC   Q6IPX1;
DE   RecName: Full=TBC1 domain family member 3C;
GN   Name=TBC1D3C; Synonyms=TBC1D3D;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC3G_HUMAN             Reviewed;         549 AA.
AC   Q6DHY5; A8K8H9;
DE   RecName: Full=TBC1 domain family member 3G;
GN   Name=TBC1D3G;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC3H_HUMAN             Reviewed;         549 AA.
AC   P0C7X1; A6NH17; A8MZ78;
DE   RecName: Full=TBC1 domain family member 3H;
GN   Name=TBC1D3H;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC8B_HUMAN             Reviewed;        1120 AA.
AC   Q0IIM8; B9A6K5; B9A6K6; Q5JRB7; Q6ZVX5; Q9NXE3;
DE   RecName: Full=TBC1 domain family member 8B;
GN   Name=TBC1D8B;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBC9B_HUMAN             Reviewed;        1250 AA.
AC   Q66K14; D3DWQ5; D3DWQ6; O75163; Q53EY0; Q6MZI2; Q96H49;
DE   RecName: Full=TBC1 domain family member 9B;
GN   Name=TBC1D9B; Synonyms=KIAA0676;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBCA_HUMAN              Reviewed;         108 AA.
AC   O75347;
DE   RecName: Full=Tubulin-specific chaperone A;
DE   AltName: Full=TCP1-chaperonin cofactor A;
DE   AltName: Full=Tubulin-folding cofactor A;
DE            Short=CFA;
GN   Name=TBCA;
DR   GO; GO:0051087; F:chaperone binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007023; P:post-chaperonin tubulin folding pathway; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
DR   GO; GO:0007021; P:tubulin complex assembly; IEA:InterPro.
//
ID   TBCB_HUMAN              Reviewed;         244 AA.
AC   Q99426; O00111; O00674; O14728;
DE   RecName: Full=Tubulin-folding cofactor B;
DE   AltName: Full=Cytoskeleton-associated protein 1;
DE   AltName: Full=Cytoskeleton-associated protein CKAPI;
DE   AltName: Full=Tubulin-specific chaperone B;
GN   Name=TBCB; Synonyms=CG22, CKAP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   TBCC1_HUMAN             Reviewed;         557 AA.
AC   Q9NVR7; B3KW69; D3DNU6; G5E9J4;
DE   RecName: Full=TBCC domain-containing protein 1;
GN   Name=TBCCD1;
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0051661; P:maintenance of centrosome location; IMP:UniProtKB.
DR   GO; GO:0051684; P:maintenance of Golgi location; IMP:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   TBCC_HUMAN              Reviewed;         346 AA.
AC   Q15814; Q53Y43; Q5T787;
DE   RecName: Full=Tubulin-specific chaperone C;
DE   AltName: Full=Tubulin-folding cofactor C;
DE            Short=CFC;
GN   Name=TBCC;
DR   GO; GO:0051087; F:chaperone binding; TAS:ProtInc.
DR   GO; GO:0003924; F:GTPase activity; IDA:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
//
ID   TBCD1_HUMAN             Reviewed;        1168 AA.
AC   Q86TI0; B7Z3D9; E9PGH8; Q96K82; Q9UPP4;
DE   RecName: Full=TBC1 domain family member 1;
GN   Name=TBC1D1; Synonyms=KIAA1108;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
//
ID   TBCD4_HUMAN             Reviewed;        1298 AA.
AC   O60343; A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; Q5W0B9; Q68D14;
DE   RecName: Full=TBC1 domain family member 4;
DE   AltName: Full=Akt substrate of 160 kDa;
DE            Short=AS160;
GN   Name=TBC1D4; Synonyms=AS160, KIAA0603;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031339; P:negative regulation of vesicle fusion; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB.
//
ID   TBCD5_HUMAN             Reviewed;         795 AA.
AC   Q92609; A6NP25; C9JP52;
DE   RecName: Full=TBC1 domain family member 5;
GN   Name=TBC1D5; Synonyms=KIAA0210;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBCD7_HUMAN             Reviewed;         293 AA.
AC   Q9P0N9; E7EV96; Q2TU37; Q53F44; Q5SZL7; Q86VM8; Q96MB8;
DE   RecName: Full=TBC1 domain family member 7;
DE   AltName: Full=Cell migration-inducing protein 23;
GN   Name=TBC1D7; Synonyms=TBC7; ORFNames=HSPC239;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IMP:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070848; P:response to growth factor; IMP:UniProtKB.
//
ID   TBCD8_HUMAN             Reviewed;        1140 AA.
AC   O95759; A6NDL4; A8K9W1; B9A6K4; Q53SQ4; Q9UQ32;
DE   RecName: Full=TBC1 domain family member 8;
DE   AltName: Full=AD 3;
DE   AltName: Full=Vascular Rab-GAP/TBC-containing protein;
GN   Name=TBC1D8; Synonyms=VRP;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   TBCD9_HUMAN             Reviewed;        1266 AA.
AC   Q6ZT07; A6H8U8; D3DNZ1; O94958;
DE   RecName: Full=TBC1 domain family member 9;
DE   AltName: Full=TBC1 domain family member 9A;
GN   Name=TBC1D9; Synonyms=KIAA0882, TBC1D9A;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBCD_HUMAN              Reviewed;        1192 AA.
AC   Q9BTW9; O95458; Q7L8K1; Q8IXP6; Q8NAX0; Q8WYH4; Q96E74; Q9UF82;
AC   Q9UG46; Q9Y2J3;
DE   RecName: Full=Tubulin-specific chaperone D;
DE   AltName: Full=Beta-tubulin cofactor D;
DE            Short=tfcD;
DE   AltName: Full=SSD-1;
DE   AltName: Full=Tubulin-folding cofactor D;
GN   Name=TBCD; Synonyms=KIAA0988, SSD1, TFCD; ORFNames=PP1096;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0051087; F:chaperone binding; TAS:ProtInc.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0034333; P:adherens junction assembly; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; ISS:UniProtKB.
DR   GO; GO:0031115; P:negative regulation of microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IDA:UniProtKB.
DR   GO; GO:0070830; P:tight junction assembly; ISS:UniProtKB.
//
ID   TBCEL_HUMAN             Reviewed;         424 AA.
AC   Q5QJ74; Q0VAN6;
DE   RecName: Full=Tubulin-specific chaperone cofactor E-like protein;
DE            Short=EL;
DE   AltName: Full=Leucine-rich repeat-containing protein 35;
GN   Name=TBCEL; Synonyms=LRRC35;
//
ID   TBCE_HUMAN              Reviewed;         527 AA.
AC   Q15813; A8K8C2; B7Z3P1;
DE   RecName: Full=Tubulin-specific chaperone E;
DE   AltName: Full=Tubulin-folding cofactor E;
GN   Name=TBCE;
DR   GO; GO:0051087; F:chaperone binding; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0014889; P:muscle atrophy; IEA:Ensembl.
DR   GO; GO:0048936; P:peripheral nervous system neuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IDA:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
//
ID   TBCK_HUMAN              Reviewed;         893 AA.
AC   Q8TEA7; B9A6J1; Q4W5B3; Q4W5E1; Q6NUP4; Q8N7M8; Q8WW57; Q96GV6;
AC   Q9P080;
DE   RecName: Full=TBC domain-containing protein kinase-like protein;
GN   Name=TBCK; Synonyms=TBCKL; ORFNames=HSPC302;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
//
ID   TBD2A_HUMAN             Reviewed;         928 AA.
AC   Q9BYX2; B3KWD1; B4DQ05; B9A6J7; Q59EU0; Q5TBQ5; Q6IPC7; Q7L1K8;
AC   Q8WYT1; Q9H6A2; Q9NSH4;
DE   RecName: Full=TBC1 domain family member 2A;
DE   AltName: Full=Armus;
DE   AltName: Full=Prostate antigen recognized and identified by SEREX 1;
DE            Short=PARIS-1;
GN   Name=TBC1D2; Synonyms=PARIS1, PP8997, TBC1D2A;
DR   GO; GO:0045296; F:cadherin binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; IDA:UniProtKB.
//
ID   TBD2B_HUMAN             Reviewed;         963 AA.
AC   Q9UPU7; A7MD42; Q8N1F9; Q9NXM0;
DE   RecName: Full=TBC1 domain family member 2B;
GN   Name=TBC1D2B; Synonyms=KIAA1055;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
//
ID   TBD_HUMAN               Reviewed;         453 AA.
AC   Q9UJT1; B4DPT8; B4DW01; D3DU02; E9PCA7; E9PCQ8; Q5KU36; Q9BWG9;
AC   Q9H7Z8;
DE   RecName: Full=Tubulin delta chain;
DE   AltName: Full=Delta-tubulin;
GN   Name=TUBD1; Synonyms=TUBD;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TBE_HUMAN               Reviewed;         475 AA.
AC   Q9UJT0; Q5H8W8; Q8NEG3;
DE   RecName: Full=Tubulin epsilon chain;
DE   AltName: Full=Epsilon-tubulin;
GN   Name=TUBE1; Synonyms=TUBE;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0007098; P:centrosome cycle; TAS:ProtInc.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBG1_HUMAN              Reviewed;         451 AA.
AC   P23258; Q53X79; Q9BW59;
DE   RecName: Full=Tubulin gamma-1 chain;
DE   AltName: Full=Gamma-1-tubulin;
DE   AltName: Full=Gamma-tubulin complex component 1;
DE            Short=GCP-1;
GN   Name=TUBG1; Synonyms=TUBG;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000212; P:meiotic spindle organization; ISS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBG2_HUMAN              Reviewed;         451 AA.
AC   Q9NRH3; A6NDI4; Q32NB2;
DE   RecName: Full=Tubulin gamma-2 chain;
DE   AltName: Full=Gamma-2-tubulin;
GN   Name=TUBG2;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; TAS:ProtInc.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051258; P:protein polymerization; IEA:InterPro.
//
ID   TBK1_HUMAN              Reviewed;         729 AA.
AC   Q9UHD2; A8K4S4; Q8IYV3; Q9NUJ5;
DE   RecName: Full=Serine/threonine-protein kinase TBK1;
DE            EC=2.7.11.1;
DE   AltName: Full=NF-kappa-B-activating kinase;
DE   AltName: Full=T2K;
DE   AltName: Full=TANK-binding kinase 1;
GN   Name=TBK1; Synonyms=NAK;
DR   GuidetoPHARMACOLOGY; 2237; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:Ensembl.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; NAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:UniProtKB.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IDA:BHF-UCL.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IDA:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; NAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; TAS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032606; P:type I interferon production; TAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TBKB1_HUMAN             Reviewed;         615 AA.
AC   A7MCY6; B2RZG6; O94873; Q14DW3;
DE   RecName: Full=TANK-binding kinase 1-binding protein 1;
DE            Short=TBK1-binding protein 1;
GN   Name=TBKBP1; Synonyms=KIAA0775, SINTBAD;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
//
ID   TBL1R_HUMAN             Reviewed;         514 AA.
AC   Q9BZK7; D3DNQ9; Q14DC3; Q9H2I1; Q9H9A1;
DE   RecName: Full=F-box-like/WD repeat-containing protein TBL1XR1;
DE   AltName: Full=Nuclear receptor corepressor/HDAC3 complex subunit TBLR1;
DE   AltName: Full=TBL1-related protein 1;
DE   AltName: Full=Transducin beta-like 1X-related protein 1;
GN   Name=TBL1XR1; Synonyms=IRA1, TBLR1;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBL1X_HUMAN             Reviewed;         577 AA.
AC   O60907; A8K044; A8K4J7; Q86UY2;
DE   RecName: Full=F-box-like/WD repeat-containing protein TBL1X;
DE   AltName: Full=SMAP55;
DE   AltName: Full=Transducin beta-like protein 1X;
DE   AltName: Full=Transducin-beta-like protein 1, X-linked;
GN   Name=TBL1X; Synonyms=TBL1;
DR   GO; GO:0008013; F:beta-catenin binding; IPI:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBL1Y_HUMAN             Reviewed;         522 AA.
AC   Q9BQ87; A1L4B3;
DE   RecName: Full=F-box-like/WD repeat-containing protein TBL1Y;
DE   AltName: Full=Transducin beta-like protein 1Y;
DE   AltName: Full=Transducin-beta-like protein 1, Y-linked;
GN   Name=TBL1Y; Synonyms=TBL1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBL2_HUMAN              Reviewed;         447 AA.
AC   Q9Y4P3; Q9UQE2;
DE   RecName: Full=Transducin beta-like protein 2;
DE   AltName: Full=WS beta-transducin repeats protein;
DE            Short=WS-betaTRP;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 13 protein;
GN   Name=TBL2; Synonyms=WBSCR13; ORFNames=UNQ563/PRO1125;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   TBL3_HUMAN              Reviewed;         808 AA.
AC   Q12788; Q59GD6; Q8IVB7; Q96A78;
DE   RecName: Full=Transducin beta-like protein 3;
DE   AltName: Full=WD repeat-containing protein SAZD;
GN   Name=TBL3; Synonyms=SAZD;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0007199; P:G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:GOC.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
//
ID   TBPL1_HUMAN             Reviewed;         186 AA.
AC   P62380; A8K8F5; O95753; Q9BWD5; Q9Z2Z0;
DE   RecName: Full=TATA box-binding protein-like protein 1;
DE            Short=TBP-like protein 1;
DE   AltName: Full=21 kDa TBP-like protein;
DE   AltName: Full=Second TBP of unique DNA protein;
DE            Short=STUD;
DE   AltName: Full=TATA box-binding protein-related factor 2;
DE            Short=TBP-related factor 2;
DE   AltName: Full=TBP-like factor;
DE   AltName: Full=TBP-related protein;
GN   Name=TBPL1; Synonyms=TLF, TLP, TLP21, TRF2, TRP;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:UniProtKB.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:Ensembl.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:UniProtKB.
//
ID   TBPL2_HUMAN             Reviewed;         375 AA.
AC   Q6SJ96; Q17RU8;
DE   RecName: Full=TATA box-binding protein-like protein 2;
DE            Short=TBP-like protein 2;
DE   AltName: Full=TATA box-binding protein-related factor 3;
DE            Short=TBP-related factor 3;
GN   Name=TBPL2; Synonyms=TBP2, TRF3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006352; P:DNA-templated transcription, initiation; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
//
ID   TBP_HUMAN               Reviewed;         339 AA.
AC   P20226; B4E3B3; F5H869; Q16845; Q6IBM6; Q9UC02;
DE   RecName: Full=TATA-box-binding protein;
DE   AltName: Full=TATA sequence-binding protein;
DE   AltName: Full=TATA-binding factor;
DE   AltName: Full=TATA-box factor;
DE   AltName: Full=Transcription initiation factor TFIID TBP subunit;
GN   Name=TBP; Synonyms=GTF2D1, TF2D, TFIID;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IDA:MGI.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IC:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TBR1_HUMAN              Reviewed;         682 AA.
AC   Q16650; B2R6G5; Q14DC5; Q53TH0; Q56A81;
DE   RecName: Full=T-box brain protein 1;
DE            Short=T-brain-1;
DE            Short=TBR-1;
DE   AltName: Full=TES-56;
GN   Name=TBR1;
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0030902; P:hindbrain development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010975; P:regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0010092; P:specification of organ identity; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBRG1_HUMAN             Reviewed;         411 AA.
AC   Q3YBR2; Q53GJ5; Q66ZJ6; Q69YS7; Q8TCS4; Q8TEI4; Q96SV0;
DE   RecName: Full=Transforming growth factor beta regulator 1;
DE   AltName: Full=Nuclear interactor of ARF and Mdm2;
GN   Name=TBRG1; Synonyms=NIAM;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:HGNC.
DR   GO; GO:0006260; P:DNA replication; IMP:HGNC.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:0032066; P:nucleolus to nucleoplasm transport; IDA:HGNC.
DR   GO; GO:0050821; P:protein stabilization; IMP:HGNC.
//
ID   TBRG4_HUMAN             Reviewed;         631 AA.
AC   Q969Z0; A4D2L2; A4D2L3; D3DVL5; D3DVL6; O14710; Q53GI8; Q8NDM4;
AC   Q9BUC6; Q9Y2F6;
DE   RecName: Full=Protein TBRG4;
DE   AltName: Full=Cell cycle progression restoration protein 2;
DE            Short=Cell cycle progression protein 2;
DE   AltName: Full=FAST kinase domain-containing protein 4;
DE   AltName: Full=Transforming growth factor beta regulator 4;
GN   Name=TBRG4; Synonyms=CPR2, FASTKD4, KIAA0948;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0045333; P:cellular respiration; ISS:UniProtKB.
DR   GO; GO:0000080; P:mitotic G1 phase; TAS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
//
ID   TBX10_HUMAN             Reviewed;         385 AA.
AC   O75333; Q14D64; Q86XS3;
DE   RecName: Full=T-box transcription factor TBX10;
DE            Short=T-box protein 10;
GN   Name=TBX10; Synonyms=TBX7;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBX15_HUMAN             Reviewed;         602 AA.
AC   Q96SF7; Q08E76; Q5JT54; Q5T9S7;
DE   RecName: Full=T-box transcription factor TBX15;
DE            Short=T-box protein 15;
DE   AltName: Full=T-box transcription factor TBX14;
DE            Short=T-box protein 14;
GN   Name=TBX15; Synonyms=TBX14;
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
//
ID   TBX19_HUMAN             Reviewed;         448 AA.
AC   O60806; Q52M53;
DE   RecName: Full=T-box transcription factor TBX19;
DE            Short=T-box protein 19;
DE   AltName: Full=T-box factor, pituitary;
GN   Name=TBX19; Synonyms=TPIT;
DR   GO; GO:0001158; F:enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045595; P:regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBX18_HUMAN             Reviewed;         607 AA.
AC   O95935; A2RU13; Q7Z6U4; Q9UJI6;
DE   RecName: Full=T-box transcription factor TBX18;
DE            Short=T-box protein 18;
GN   Name=TBX18;
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:BHF-UCL.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0060829; P:negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:GOC.
DR   GO; GO:0022409; P:positive regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:2000729; P:positive regulation of mesenchymal cell proliferation involved in ureter development; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0003163; P:sinoatrial node development; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   TBX1_HUMAN              Reviewed;         398 AA.
AC   O43435; C6G493; C6G494; O43436; Q96RJ2;
DE   RecName: Full=T-box transcription factor TBX1;
DE            Short=T-box protein 1;
DE   AltName: Full=Testis-specific T-box protein;
GN   Name=TBX1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.
DR   GO; GO:0035909; P:aorta morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; ISS:UniProtKB.
DR   GO; GO:0048514; P:blood vessel morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; ISS:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0090103; P:cochlea morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060982; P:coronary artery morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007368; P:determination of left/right symmetry; ISS:UniProtKB.
DR   GO; GO:0042471; P:ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0070166; P:enamel mineralization; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IMP:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0001945; P:lymph vessel development; ISS:UniProtKB.
DR   GO; GO:0097152; P:mesenchymal cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0007498; P:mesoderm development; ISS:UniProtKB.
DR   GO; GO:0042474; P:middle ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0042693; P:muscle cell fate commitment; ISS:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; ISS:UniProtKB.
DR   GO; GO:0048644; P:muscle organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060415; P:muscle tissue morphogenesis; ISS:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; ISS:UniProtKB.
DR   GO; GO:2001054; P:negative regulation of mesenchymal cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.
DR   GO; GO:0071600; P:otic vesicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0042473; P:outer ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060017; P:parathyroid gland development; IMP:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; ISS:UniProtKB.
DR   GO; GO:0060037; P:pharyngeal system development; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0072513; P:positive regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:2001037; P:positive regulation of tongue muscle cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:2000027; P:regulation of organ morphogenesis; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0048384; P:retinoic acid receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; ISS:UniProtKB.
DR   GO; GO:0035176; P:social behavior; ISS:UniProtKB.
DR   GO; GO:0060023; P:soft palate development; IMP:UniProtKB.
DR   GO; GO:0048538; P:thymus development; IMP:UniProtKB.
DR   GO; GO:0030878; P:thyroid gland development; ISS:UniProtKB.
DR   GO; GO:0043587; P:tongue morphogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021644; P:vagus nerve morphogenesis; ISS:UniProtKB.
//
ID   TBX20_HUMAN             Reviewed;         447 AA.
AC   Q9UMR3; A4D1Y6; Q000T4; Q0IJ70; Q0VAS1; Q9Y2N5;
DE   RecName: Full=T-box transcription factor TBX20;
DE            Short=T-box protein 20;
GN   Name=TBX20;
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003180; P:aortic valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0008015; P:blood circulation; IEA:Ensembl.
DR   GO; GO:0003207; P:cardiac chamber formation; ISS:BHF-UCL.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003215; P:cardiac right ventricle morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003279; P:cardiac septum development; ISS:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; ISS:BHF-UCL.
DR   GO; GO:0036306; P:embryonic heart tube elongation; IEA:Ensembl.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003272; P:endocardial cushion formation; ISS:BHF-UCL.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001706; P:endoderm formation; ISS:BHF-UCL.
DR   GO; GO:0035922; P:foramen ovale closure; IMP:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; ISS:BHF-UCL.
DR   GO; GO:0048370; P:lateral mesoderm formation; ISS:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
DR   GO; GO:0010991; P:negative regulation of SMAD protein complex assembly; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0003344; P:pericardium morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0003193; P:pulmonary valve formation; ISS:BHF-UCL.
DR   GO; GO:0060577; P:pulmonary vein morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003175; P:tricuspid valve development; ISS:BHF-UCL.
DR   GO; GO:0021524; P:visceral motor neuron differentiation; ISS:BHF-UCL.
//
ID   TBX21_HUMAN             Reviewed;         535 AA.
AC   Q9UL17;
DE   RecName: Full=T-box transcription factor TBX21;
DE            Short=T-box protein 21;
DE   AltName: Full=T-cell-specific T-box transcription factor T-bet;
DE   AltName: Full=Transcription factor TBLYM;
GN   Name=TBX21; Synonyms=TBET, TBLYM;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0072676; P:lymphocyte migration; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBX22_HUMAN             Reviewed;         520 AA.
AC   Q9Y458; Q5JZ06; Q96LC0; Q9HBF1;
DE   RecName: Full=T-box transcription factor TBX22;
DE            Short=T-box protein 22;
GN   Name=TBX22; Synonyms=TBOX22;
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBX2_HUMAN              Reviewed;         712 AA.
AC   Q13207; Q16424; Q7Z647;
DE   RecName: Full=T-box transcription factor TBX2;
DE            Short=T-box protein 2;
GN   Name=TBX2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0035909; P:aorta morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0036302; P:atrioventricular canal development; ISS:BHF-UCL.
DR   GO; GO:0048738; P:cardiac muscle tissue development; ISS:BHF-UCL.
DR   GO; GO:0007569; P:cell aging; IDA:UniProtKB.
DR   GO; GO:0090398; P:cellular senescence; IDA:UniProtKB.
DR   GO; GO:0060560; P:developmental growth involved in morphogenesis; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060596; P:mammary placode formation; IEA:Ensembl.
DR   GO; GO:0007521; P:muscle cell fate determination; ISS:BHF-UCL.
DR   GO; GO:1901211; P:negative regulation of cardiac chamber formation; ISS:BHF-UCL.
DR   GO; GO:1901208; P:negative regulation of heart looping; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003148; P:outflow tract septum morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0060465; P:pharynx development; ISS:BHF-UCL.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0003256; P:regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBX3_HUMAN              Reviewed;         743 AA.
AC   O15119; Q8TB20; Q9UKF8;
DE   RecName: Full=T-box transcription factor TBX3;
DE            Short=T-box protein 3;
GN   Name=TBX3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; IMP:UniProtKB.
DR   GO; GO:0003167; P:atrioventricular bundle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0060444; P:branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0060923; P:cardiac muscle cell fate commitment; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IDA:UniProtKB.
DR   GO; GO:0090398; P:cellular senescence; IDA:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IMP:UniProtKB.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0030540; P:female genitalia development; IMP:UniProtKB.
DR   GO; GO:0046884; P:follicle-stimulating hormone secretion; IMP:UniProtKB.
DR   GO; GO:0035136; P:forelimb morphogenesis; IDA:MGI.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0021761; P:limbic system development; IEA:Ensembl.
DR   GO; GO:0032275; P:luteinizing hormone secretion; IMP:UniProtKB.
DR   GO; GO:0030539; P:male genitalia development; IMP:UniProtKB.
DR   GO; GO:0030879; P:mammary gland development; IMP:UniProtKB.
DR   GO; GO:0060596; P:mammary placode formation; IEA:Ensembl.
DR   GO; GO:0048332; P:mesoderm morphogenesis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; IDA:MGI.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000648; P:positive regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:UniProtKB.
DR   GO; GO:0060931; P:sinoatrial node cell development; IEA:Ensembl.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0010159; P:specification of organ position; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
//
ID   TBX4_HUMAN              Reviewed;         545 AA.
AC   P57082; A5PKU7; B2RMT1; B7ZLV3;
DE   RecName: Full=T-box transcription factor TBX4;
DE            Short=T-box protein 4;
GN   Name=TBX4;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035108; P:limb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TBX5_HUMAN              Reviewed;         518 AA.
AC   Q99593; A6ND77; O15301; Q96TB0; Q9Y4I2;
DE   RecName: Full=T-box transcription factor TBX5;
DE            Short=T-box protein 5;
GN   Name=TBX5;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001228; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0030262; P:apoptotic nuclear changes; IDA:UniProtKB.
DR   GO; GO:0060413; P:atrial septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003181; P:atrioventricular valve morphogenesis; IEA:Ensembl.
DR   GO; GO:0003166; P:bundle of His development; IEA:Ensembl.
DR   GO; GO:0003218; P:cardiac left ventricle formation; ISS:BHF-UCL.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0060980; P:cell migration involved in coronary vasculogenesis; TAS:DFLAT.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:UniProtKB.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0003197; P:endocardial cushion development; IEA:Ensembl.
DR   GO; GO:0035136; P:forelimb morphogenesis; IMP:MGI.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IDA:UniProtKB.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IEA:Ensembl.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; TAS:DFLAT.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0060039; P:pericardium development; IDA:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051891; P:positive regulation of cardioblast differentiation; IDA:UniProtKB.
DR   GO; GO:0072513; P:positive regulation of secondary heart field cardioblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:1900117; P:regulation of execution phase of apoptosis; IC:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0003229; P:ventricular cardiac muscle tissue development; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; ISS:BHF-UCL.
//
ID   TBX6_HUMAN              Reviewed;         436 AA.
AC   O95947; Q8TAS4; Q9HA44;
DE   RecName: Full=T-box transcription factor TBX6;
DE            Short=T-box protein 6;
GN   Name=TBX6;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0023019; P:signal transduction involved in regulation of gene expression; IEA:Ensembl.
//
ID   TC1D1_HUMAN             Reviewed;         179 AA.
AC   Q8N7M0; Q06YR9; Q5VYE1;
DE   RecName: Full=Tctex1 domain-containing protein 1;
GN   Name=TCTEX1D1;
//
ID   TC1D2_HUMAN             Reviewed;         142 AA.
AC   Q8WW35; A6NCN5;
DE   RecName: Full=Tctex1 domain-containing protein 2;
GN   Name=TCTEX1D2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TC1D3_HUMAN             Reviewed;         198 AA.
AC   Q8IZS6;
DE   RecName: Full=Tctex1 domain-containing protein 3;
DE   AltName: Full=T-complex testis-specific protein 3;
DE   AltName: Full=T-complex-associated testis-expressed protein 3;
DE            Short=Tcte-3;
GN   Name=TCTE3; Synonyms=TCTEX1D3;
DR   GO; GO:0003774; F:motor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   TC1D4_HUMAN             Reviewed;         221 AA.
AC   Q5JR98;
DE   RecName: Full=Tctex1 domain-containing protein 4;
DE   AltName: Full=Protein N22.1;
DE   AltName: Full=Tctex-2-beta;
GN   Name=TCTEX1D4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TCAIM_HUMAN             Reviewed;         496 AA.
AC   Q8N3R3; A8K9P1; Q0P5T9; Q495R1; Q495R3; Q4G0M4; Q6GMU8;
DE   RecName: Full=T-cell activation inhibitor, mitochondrial;
DE   AltName: Full=Tolerance associated gene-1 protein;
DE            Short=TOAG-1;
GN   Name=TCAIM; Synonyms=C3orf23, TOAG1;
//
ID   TCAL1_HUMAN             Reviewed;         157 AA.
AC   Q15170; Q9UJQ9;
DE   RecName: Full=Transcription elongation factor A protein-like 1;
DE            Short=TCEA-like protein 1;
DE   AltName: Full=Nuclear phosphoprotein p21/SIIR;
DE   AltName: Full=Transcription elongation factor S-II protein-like 1;
GN   Name=TCEAL1; Synonyms=SIIR;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL2_HUMAN             Reviewed;         227 AA.
AC   Q9H3H9; B2R5C7;
DE   RecName: Full=Transcription elongation factor A protein-like 2;
DE            Short=TCEA-like protein 2;
DE   AltName: Full=Transcription elongation factor S-II protein-like 2;
GN   Name=TCEAL2; ORFNames=My048, MY0876G0;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL3_HUMAN             Reviewed;         200 AA.
AC   Q969E4; D3DXA4;
DE   RecName: Full=Transcription elongation factor A protein-like 3;
DE            Short=TCEA-like protein 3;
DE   AltName: Full=Transcription elongation factor S-II protein-like 3;
GN   Name=TCEAL3; ORFNames=MSTP072;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL5_HUMAN             Reviewed;         206 AA.
AC   Q5H9L2; A2RUJ4;
DE   RecName: Full=Transcription elongation factor A protein-like 5;
DE            Short=TCEA-like protein 5;
DE   AltName: Full=Transcription elongation factor S-II protein-like 5;
GN   Name=TCEAL5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL4_HUMAN             Reviewed;         215 AA.
AC   Q96EI5; Q8WY12; Q9H2H1; Q9H775;
DE   RecName: Full=Transcription elongation factor A protein-like 4;
DE            Short=TCEA-like protein 4;
DE   AltName: Full=Transcription elongation factor S-II protein-like 4;
GN   Name=TCEAL4; ORFNames=NPD017;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL6_HUMAN             Reviewed;         200 AA.
AC   Q6IPX3; Q5H9J8;
DE   RecName: Full=Transcription elongation factor A protein-like 6;
DE            Short=TCEA-like protein 6;
DE   AltName: Full=Transcription elongation factor S-II protein-like 6;
GN   Name=TCEAL6;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL7_HUMAN             Reviewed;         100 AA.
AC   Q9BRU2; B3KSV2; Q96AT4;
DE   RecName: Full=Transcription elongation factor A protein-like 7;
DE            Short=TCEA-like protein 7;
DE   AltName: Full=Transcription elongation factor S-II protein-like 7;
GN   Name=TCEAL7;
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAL8_HUMAN             Reviewed;         117 AA.
AC   Q8IYN2;
DE   RecName: Full=Transcription elongation factor A protein-like 8;
DE            Short=TCEA-like protein 8;
DE   AltName: Full=Transcription elongation factor S-II protein-like 8;
GN   Name=TCEAL8;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCAM1_HUMAN             Reviewed;         712 AA.
AC   Q8IUC6; B3Y691; O75532; Q86XP8; Q96GA0;
DE   RecName: Full=TIR domain-containing adapter molecule 1;
DE            Short=TICAM-1;
DE   AltName: Full=Proline-rich, vinculin and TIR domain-containing protein B;
DE   AltName: Full=Putative NF-kappa-B-activating protein 502H;
DE   AltName: Full=Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta;
DE            Short=MyD88-3;
DE            Short=TIR domain-containing adapter protein inducing IFN-beta;
GN   Name=TICAM1; Synonyms=PRVTIRB, TRIF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0002281; P:macrophage activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; IEA:Ensembl.
DR   GO; GO:0043496; P:regulation of protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IMP:MGI.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TCAM2_HUMAN             Reviewed;         235 AA.
AC   Q86XR7; B3Y698; Q6JUT2;
DE   RecName: Full=TIR domain-containing adapter molecule 2;
DE            Short=TICAM-2;
DE   AltName: Full=Putative NF-kappa-B-activating protein 502;
DE   AltName: Full=TRIF-related adapter molecule;
DE   AltName: Full=Toll-like receptor adaptor protein 3;
DE   AltName: Full=Toll/interleukin-1 receptor domain-containing protein;
DE            Short=MyD88-4;
GN   Name=TICAM2; Synonyms=TIRAP3, TIRP, TRAM;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0071650; P:negative regulation of chemokine (C-C motif) ligand 5 production; IMP:UniProtKB.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0071651; P:positive regulation of chemokine (C-C motif) ligand 5 production; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:2000494; P:positive regulation of interleukin-18-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TCA_HUMAN               Reviewed;         142 AA.
AC   P01848;
DE   RecName: Full=T-cell receptor alpha chain C region;
GN   Name=TRAC; Synonyms=TCRA;
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TCEA1_HUMAN             Reviewed;         301 AA.
AC   P23193; A6NF25; A8K339; Q15563; Q6FG87;
DE   RecName: Full=Transcription elongation factor A protein 1;
DE   AltName: Full=Transcription elongation factor S-II protein 1;
DE   AltName: Full=Transcription elongation factor TFIIS.o;
GN   Name=TCEA1; Synonyms=GTF2S, TFIIS;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TCEA2_HUMAN             Reviewed;         299 AA.
AC   Q15560; B3KNM1; Q8TD37; Q8TD38;
DE   RecName: Full=Transcription elongation factor A protein 2;
DE   AltName: Full=Testis-specific S-II;
DE   AltName: Full=Transcription elongation factor S-II protein 2;
DE   AltName: Full=Transcription elongation factor TFIIS.l;
GN   Name=TCEA2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006354; P:DNA-templated transcription, elongation; NAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; NAS:UniProtKB.
//
ID   TCEA3_HUMAN             Reviewed;         348 AA.
AC   O75764; A8K2K7;
DE   RecName: Full=Transcription elongation factor A protein 3;
DE   AltName: Full=Transcription elongation factor S-II protein 3;
DE   AltName: Full=Transcription elongation factor TFIIS.h;
GN   Name=TCEA3; Synonyms=TFIISH;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCF15_HUMAN             Reviewed;         199 AA.
AC   Q12870; Q9NQQ1;
DE   RecName: Full=Transcription factor 15;
DE            Short=TCF-15;
DE   AltName: Full=Class A basic helix-loop-helix protein 40;
DE            Short=bHLHa40;
DE   AltName: Full=Paraxis;
DE   AltName: Full=Protein bHLH-EC2;
GN   Name=TCF15; Synonyms=BHLHA40, BHLHEC2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0016265; P:death; IEA:Ensembl.
DR   GO; GO:0043583; P:ear development; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl.
DR   GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCF19_HUMAN             Reviewed;         345 AA.
AC   Q9Y242; A6NCT8; B0UY11; Q0EFA8; Q13176; Q15967; Q5SQ89; Q5STD6;
AC   Q5STF5; Q9BUM2; Q9UBH7;
DE   RecName: Full=Transcription factor 19;
DE            Short=TCF-19;
DE   AltName: Full=Transcription factor SC1;
GN   Name=TCF19; Synonyms=SC1;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCF20_HUMAN             Reviewed;        1960 AA.
AC   Q9UGU0; A9JX12; O14528; Q13078; Q4V353; Q9H4M0;
DE   RecName: Full=Transcription factor 20;
DE            Short=TCF-20;
DE   AltName: Full=Nuclear factor SPBP;
DE   AltName: Full=Protein AR1;
DE   AltName: Full=Stromelysin-1 PDGF-responsive element-binding protein;
DE            Short=SPRE-binding protein;
GN   Name=TCF20; Synonyms=KIAA0292, SPBP;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCF21_HUMAN             Reviewed;         179 AA.
AC   O43680; E1P581; O43545; Q6ICV0; Q9BZ14;
DE   RecName: Full=Transcription factor 21;
DE            Short=TCF-21;
DE   AltName: Full=Capsulin;
DE   AltName: Full=Class A basic helix-loop-helix protein 23;
DE            Short=bHLHa23;
DE   AltName: Full=Epicardin;
DE   AltName: Full=Podocyte-expressed 1;
DE            Short=Pod-1;
GN   Name=TCF21; Synonyms=BHLHA23, POD1;
DR   GO; GO:0050681; F:androgen receptor binding; ISS:BHF-UCL.
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; ISS:BHF-UCL.
DR   GO; GO:0046983; F:protein dimerization activity; ISS:UniProtKB.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0014707; P:branchiomeric skeletal muscle development; ISS:UniProtKB.
DR   GO; GO:0060435; P:bronchiole development; ISS:UniProtKB.
DR   GO; GO:0060539; P:diaphragm development; ISS:UniProtKB.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0048732; P:gland development; ISS:UniProtKB.
DR   GO; GO:0032835; P:glomerulus development; ISS:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:BHF-UCL.
DR   GO; GO:0048286; P:lung alveolus development; ISS:UniProtKB.
DR   GO; GO:0060425; P:lung morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060426; P:lung vasculature development; ISS:UniProtKB.
DR   GO; GO:0072277; P:metanephric glomerular capillary formation; ISS:UniProtKB.
DR   GO; GO:0072162; P:metanephric mesenchymal cell differentiation; ISS:UniProtKB.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; ISS:BHF-UCL.
DR   GO; GO:0060766; P:negative regulation of androgen receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0060021; P:palate development; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0048608; P:reproductive structure development; ISS:UniProtKB.
DR   GO; GO:0060541; P:respiratory system development; ISS:UniProtKB.
DR   GO; GO:0060008; P:Sertoli cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007530; P:sex determination; ISS:UniProtKB.
DR   GO; GO:0048536; P:spleen development; ISS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; ISS:BHF-UCL.
DR   GO; GO:0001944; P:vasculature development; ISS:BHF-UCL.
//
ID   TCF23_HUMAN             Reviewed;         214 AA.
AC   Q7RTU1; B2RNZ3;
DE   RecName: Full=Transcription factor 23;
DE            Short=TCF-23;
DE   AltName: Full=Class A basic helix-loop-helix protein 24;
DE            Short=bHLHa24;
GN   Name=TCF23; Synonyms=BHLHA24;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
//
ID   TCF24_HUMAN             Reviewed;         167 AA.
AC   Q7RTU0; H3BPR9;
DE   RecName: Full=Transcription factor 24;
DE            Short=TCF-24;
GN   Name=TCF24;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCF25_HUMAN             Reviewed;         676 AA.
AC   Q9BQ70; Q2MK75; Q9UPV3;
DE   RecName: Full=Transcription factor 25;
DE            Short=TCF-25;
DE   AltName: Full=Nuclear localized protein 1;
GN   Name=TCF25; Synonyms=KIAA1049, NULP1; ORFNames=FKSG26;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0007507; P:heart development; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCF7_HUMAN              Reviewed;         384 AA.
AC   P36402; B3KSH3; Q86WR9; Q9UKI4;
DE   RecName: Full=Transcription factor 7;
DE            Short=TCF-7;
DE   AltName: Full=T-cell-specific transcription factor 1;
DE            Short=T-cell factor 1;
DE            Short=TCF-1;
GN   Name=TCF7; Synonyms=TCF1;
DR   GO; GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0046632; P:alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0044336; P:canonical Wnt signaling pathway involved in negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0071353; P:cellular response to interleukin-4; IDA:UniProtKB.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0030538; P:embryonic genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0048619; P:embryonic hindgut morphogenesis; IEA:Ensembl.
DR   GO; GO:0048699; P:generation of neurons; IBA:RefGenome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0033153; P:T cell receptor V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCFL5_HUMAN             Reviewed;         500 AA.
AC   Q9UL49; O94771; Q9BYW0;
DE   RecName: Full=Transcription factor-like 5 protein;
DE   AltName: Full=Cha transcription factor;
DE   AltName: Full=HPV-16 E2-binding protein 1;
DE            Short=E2BP-1;
GN   Name=TCFL5; Synonyms=CHA, E2BP1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045595; P:regulation of cell differentiation; IEP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TCHL1_HUMAN             Reviewed;         904 AA.
AC   Q5QJ38; B2RPK8; Q5VTJ9;
DE   RecName: Full=Trichohyalin-like protein 1;
DE   AltName: Full=Basalin;
DE   AltName: Full=Protein S100-A17;
DE   AltName: Full=S100 calcium-binding protein A17;
GN   Name=TCHHL1; Synonyms=S100A17, THHL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   TCHP_HUMAN              Reviewed;         498 AA.
AC   Q9BT92; Q8NAG0;
DE   RecName: Full=Trichoplein keratin filament-binding protein;
DE            Short=Protein TCHP;
DE   AltName: Full=Mitochondrial protein with oncostatic activity;
DE            Short=Mitostatin;
DE   AltName: Full=Tumor suppressor protein;
GN   Name=TCHP;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
//
ID   TCL1A_HUMAN             Reviewed;         114 AA.
AC   P56279; Q6IBK7;
DE   RecName: Full=T-cell leukemia/lymphoma protein 1A;
DE   AltName: Full=Oncogene TCL-1;
DE            Short=Oncogene TCL1;
DE   AltName: Full=Protein p14 TCL1;
GN   Name=TCL1A; Synonyms=TCL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   TCL1B_HUMAN             Reviewed;         128 AA.
AC   O95988; A6NEK7; Q6IAR7; Q9UBQ4;
DE   RecName: Full=T-cell leukemia/lymphoma protein 1B;
DE   AltName: Full=Oncogene TCL-1B;
DE            Short=Oncogene TCL1B;
DE   AltName: Full=SYN-1;
DE   AltName: Full=Syncytiotrophoblast-specific protein;
DE   AltName: Full=TCL1/MTCP1-like protein 1;
GN   Name=TCL1B; Synonyms=TCL1;
//
ID   TCO1_HUMAN              Reviewed;         433 AA.
AC   P20061; A8KAC5; Q8WV77;
DE   RecName: Full=Transcobalamin-1;
DE            Short=TC-1;
DE   AltName: Full=Haptocorrin;
DE            Short=HC;
DE   AltName: Full=Protein R;
DE   AltName: Full=Transcobalamin I;
DE            Short=TC I;
DE            Short=TCI;
DE   Flags: Precursor;
GN   Name=TCN1; Synonyms=TC1;
DR   GO; GO:0031419; F:cobalamin binding; IBA:RefGenome.
DR   GO; GO:0009235; P:cobalamin metabolic process; IBA:RefGenome.
DR   GO; GO:0015889; P:cobalamin transport; TAS:ProtInc.
DR   GO; GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   TCO2_HUMAN              Reviewed;         427 AA.
AC   P20062; Q96FD4; Q9BVI8; Q9UCI5; Q9UCI6; Q9UDM0;
DE   RecName: Full=Transcobalamin-2;
DE            Short=TC-2;
DE   AltName: Full=Transcobalamin II;
DE            Short=TC II;
DE            Short=TCII;
DE   Flags: Precursor;
GN   Name=TCN2; Synonyms=TC2;
DR   GO; GO:0031419; F:cobalamin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009235; P:cobalamin metabolic process; IBA:RefGenome.
DR   GO; GO:0015889; P:cobalamin transport; TAS:ProtInc.
DR   GO; GO:0006824; P:cobalt ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   TCOF_HUMAN              Reviewed;        1488 AA.
AC   Q13428; A0JLU0; B4E111; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860;
DE   RecName: Full=Treacle protein;
DE   AltName: Full=Treacher Collins syndrome protein;
GN   Name=TCOF1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IEA:Ensembl.
//
ID   TCP10_HUMAN             Reviewed;         353 AA.
AC   Q12799; Q5JR60; Q6P4F4;
DE   RecName: Full=T-complex protein 10A homolog;
GN   Name=TCP10; Synonyms=TCP10A;
//
ID   TCP11_HUMAN             Reviewed;         503 AA.
AC   Q8WWU5; B2RCE9; B3KQ27; B7Z7B5; B7Z7G1; B7Z7H4; B7Z7S8; E7EP29;
AC   J3KNG1; Q8NF85; Q9NQZ9; Q9NR39;
DE   RecName: Full=T-complex protein 11 homolog;
GN   Name=TCP11;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TCP1L_HUMAN             Reviewed;         215 AA.
AC   Q8TDR4; Q53EW0; Q96LN5;
DE   RecName: Full=T-complex protein 10A homolog 2;
DE            Short=T-complex protein 10A-2;
DE            Short=TCP10A-2;
DE   AltName: Full=TCP10-like;
GN   Name=TCP10L; ORFNames=PRED77;
//
ID   TCP2L_HUMAN             Reviewed;         353 AA.
AC   B9ZVM9;
DE   RecName: Full=Putative t-complex protein 10A homolog 2;
DE   AltName: Full=T-complex 10-like protein 2;
GN   Name=TCP10L2;
//
ID   TCP4_HUMAN              Reviewed;         127 AA.
AC   P53999; Q96L29;
DE   RecName: Full=Activated RNA polymerase II transcriptional coactivator p15;
DE   AltName: Full=Positive cofactor 4;
DE            Short=PC4;
DE   AltName: Full=SUB1 homolog;
DE   AltName: Full=p14;
GN   Name=SUB1; Synonyms=PC4, RPO2TC1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TCPA_HUMAN              Reviewed;         556 AA.
AC   P17987; E1P5B2; Q15556; Q5TCM3;
DE   RecName: Full=T-complex protein 1 subunit alpha;
DE            Short=TCP-1-alpha;
DE   AltName: Full=CCT-alpha;
GN   Name=TCP1; Synonyms=CCT1, CCTA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0007021; P:tubulin complex assembly; NAS:UniProtKB.
//
ID   TCPB_HUMAN              Reviewed;         535 AA.
AC   P78371; A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; Q14D36; Q6IAT3;
DE   RecName: Full=T-complex protein 1 subunit beta;
DE            Short=TCP-1-beta;
DE   AltName: Full=CCT-beta;
GN   Name=CCT2; Synonyms=99D8.1, CCTB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; IMP:MGI.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   TCPD_HUMAN              Reviewed;         539 AA.
AC   P50991; B2R6I3; B7Z8B1; F5H5W3; O14870; Q53QP9; Q96C51;
DE   RecName: Full=T-complex protein 1 subunit delta;
DE            Short=TCP-1-delta;
DE   AltName: Full=CCT-delta;
DE   AltName: Full=Stimulator of TAR RNA-binding;
GN   Name=CCT4; Synonyms=CCTD, SRB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
//
ID   TCPE_HUMAN              Reviewed;         541 AA.
AC   P48643; A8JZY8; A8K2X8; B4DYD8;
DE   RecName: Full=T-complex protein 1 subunit epsilon;
DE            Short=TCP-1-epsilon;
DE   AltName: Full=CCT-epsilon;
GN   Name=CCT5; Synonyms=CCTE, KIAA0098;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IPI:UniProt.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
//
ID   TCPG_HUMAN              Reviewed;         545 AA.
AC   P49368; A6NE14; Q5SZY1; Q9BR64;
DE   RecName: Full=T-complex protein 1 subunit gamma;
DE            Short=TCP-1-gamma;
DE   AltName: Full=CCT-gamma;
DE   AltName: Full=hTRiC5;
GN   Name=CCT3; Synonyms=CCTG, TRIC5;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
//
ID   TCPH_HUMAN              Reviewed;         543 AA.
AC   Q99832; A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; O14871; Q6FI26;
DE   RecName: Full=T-complex protein 1 subunit eta;
DE            Short=TCP-1-eta;
DE   AltName: Full=CCT-eta;
DE   AltName: Full=HIV-1 Nef-interacting protein;
GN   Name=CCT7; Synonyms=CCTH, NIP7-1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
//
ID   TCPQL_HUMAN             Reviewed;         557 AA.
AC   A6NM43;
DE   RecName: Full=Putative T-complex protein 1 subunit theta-like 1;
GN   Name=CCT8L1P; Synonyms=CCT8L1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
//
ID   TCPQM_HUMAN             Reviewed;         557 AA.
AC   Q96SF2; A4QPH3; Q9UJS3;
DE   RecName: Full=Putative T-complex protein 1 subunit theta-like 2;
GN   Name=CCT8L2; Synonyms=CESK1;
DR   GO; GO:0005253; F:anion channel activity; TAS:ProtInc.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015269; F:calcium-activated potassium channel activity; TAS:ProtInc.
DR   GO; GO:0006820; P:anion transport; TAS:GOC.
DR   GO; GO:0044267; P:cellular protein metabolic process; IEA:InterPro.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   TCPQ_HUMAN              Reviewed;         548 AA.
AC   P50990; A6NN54; B4DEM7; B4DQH4; Q4VBP8;
DE   RecName: Full=T-complex protein 1 subunit theta;
DE            Short=TCP-1-theta;
DE   AltName: Full=CCT-theta;
DE   AltName: Full=Renal carcinoma antigen NY-REN-15;
GN   Name=CCT8; Synonyms=C21orf112, CCTQ, KIAA0002;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042623; F:ATPase activity, coupled; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   TCPR1_HUMAN             Reviewed;        1165 AA.
AC   Q7Z6L1; A8KAD1; B3KPZ1; C9J024; F5GX57; Q96EB0; Q9P2I9; Q9UFR6;
DE   RecName: Full=Tectonin beta-propeller repeat-containing protein 1;
GN   Name=TECPR1; Synonyms=KIAA1358;
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000046; P:autophagic vacuole fusion; IMP:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IDA:UniProtKB.
//
ID   TCPR2_HUMAN             Reviewed;        1411 AA.
AC   O15040; A5PKY3; A6NFY9; A7E2X3; H0YMM9; Q9UEG6;
DE   RecName: Full=Tectonin beta-propeller repeat-containing protein 2;
DE   AltName: Full=WD repeat-containing protein KIAA0329/KIAA0297;
GN   Name=TECPR2; Synonyms=KIAA0297, KIAA0329;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   TCPW_HUMAN              Reviewed;         530 AA.
AC   Q92526; B4DX20; B4DYB0; Q8TC34;
DE   RecName: Full=T-complex protein 1 subunit zeta-2;
DE            Short=TCP-1-zeta-2;
DE   AltName: Full=CCT-zeta-2;
DE   AltName: Full=CCT-zeta-like;
DE   AltName: Full=TCP-1-zeta-like;
DE   AltName: Full=Testis-specific Tcp20;
DE   AltName: Full=Testis-specific protein TSA303;
GN   Name=CCT6B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008565; F:protein transporter activity; TAS:ProtInc.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006457; P:protein folding; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; TAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   TCPZ_HUMAN              Reviewed;         531 AA.
AC   P40227; A6NCD2; Q3KP28; Q75LP4; Q96S46;
DE   RecName: Full=T-complex protein 1 subunit zeta;
DE            Short=TCP-1-zeta;
DE   AltName: Full=Acute morphine dependence-related protein 2;
DE   AltName: Full=CCT-zeta-1;
DE   AltName: Full=HTR3;
DE   AltName: Full=Tcp20;
GN   Name=CCT6A; Synonyms=CCT6, CCTZ;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
//
ID   TCRG1_HUMAN             Reviewed;        1098 AA.
AC   O14776; Q2NKN2; Q59EA1;
DE   RecName: Full=Transcription elongation regulator 1;
DE   AltName: Full=TATA box-binding protein-associated factor 2S;
DE   AltName: Full=Transcription factor CA150;
GN   Name=TCERG1; Synonyms=CA150, TAF2S;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TCRGL_HUMAN             Reviewed;         586 AA.
AC   Q5VWI1; Q5VWI2; Q86XM8;
DE   RecName: Full=Transcription elongation regulator 1-like protein;
GN   Name=TCERG1L;
//
ID   TCTA_HUMAN              Reviewed;         103 AA.
AC   P57738; B2R4I4; Q6I9U4; Q9BSB0;
DE   RecName: Full=T-cell leukemia translocation-altered gene protein;
DE   AltName: Full=T-cell leukemia translocation-associated gene protein;
GN   Name=TCTA;
//
ID   TCTE1_HUMAN             Reviewed;         501 AA.
AC   Q5JU00; B4DX59; Q8IYS6;
DE   RecName: Full=T-complex-associated testis-expressed protein 1;
DE            Short=Tcte-1;
GN   Name=TCTE1;
//
ID   TCTP8_HUMAN             Reviewed;         139 AA.
AC   Q9HAU6;
DE   RecName: Full=Putative translationally-controlled tumor protein-like protein TPT1P8;
DE   AltName: Full=Putative apoptosis inhibitor FKSG2;
GN   Name=TPT1P8; ORFNames=FKSG2;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   TCTP_HUMAN              Reviewed;         172 AA.
AC   P13693; B2R7E5; Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70;
DE   RecName: Full=Translationally-controlled tumor protein;
DE            Short=TCTP;
DE   AltName: Full=Fortilin;
DE   AltName: Full=Histamine-releasing factor;
DE            Short=HRF;
DE   AltName: Full=p23;
GN   Name=TPT1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006816; P:calcium ion transport; IC:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IC:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:2000384; P:negative regulation of ectoderm development; IEA:Ensembl.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IMP:MGI.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IEP:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IEA:Ensembl.
//
ID   TDGF1_HUMAN             Reviewed;         188 AA.
AC   P13385; Q8TCC1;
DE   RecName: Full=Teratocarcinoma-derived growth factor 1;
DE   AltName: Full=Cripto-1 growth factor;
DE            Short=CRGF;
DE   AltName: Full=Epidermal growth factor-like cripto protein CR1;
DE   Flags: Precursor;
GN   Name=TDGF1; Synonyms=CRIPTO;
DR   GO; GO:0008083; F:growth factor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:UniProtKB.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; ISS:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; TAS:UniProtKB.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0044344; P:cellular response to fibroblast growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IDA:UniProtKB.
DR   GO; GO:0071354; P:cellular response to interleukin-6; IDA:UniProtKB.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0009790; P:embryo development; TAS:UniProtKB.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; TAS:UniProtKB.
DR   GO; GO:0001763; P:morphogenesis of a branching structure; TAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009966; P:regulation of signal transduction; IDA:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   TDGF3_HUMAN             Reviewed;         188 AA.
AC   P51864;
DE   RecName: Full=Putative teratocarcinoma-derived growth factor 3;
DE   AltName: Full=Cripto-3 growth factor;
DE   AltName: Full=Epidermal growth factor-like cripto protein CR3;
DE   AltName: Full=Teratocarcinoma-derived growth factor 1 pseudogene 3;
GN   Name=TDGF1P3; Synonyms=CRIPTO3, TDGF2, TDGF3;
DR   GO; GO:0008083; F:growth factor activity; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   TDG_HUMAN               Reviewed;         410 AA.
AC   Q13569; Q8IUZ6; Q8IZM3;
DE   RecName: Full=G/T mismatch-specific thymine DNA glycosylase;
DE            EC=3.2.2.29;
DE   AltName: Full=Thymine-DNA glycosylase;
DE            Short=hTDG;
GN   Name=TDG;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0019104; F:DNA N-glycosylase activity; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0030983; F:mismatched DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0008263; F:pyrimidine-specific mismatch base pair DNA N-glycosylase activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:Ensembl.
DR   GO; GO:0043566; F:structure-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0006285; P:base-excision repair, AP site formation; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0045008; P:depyrimidination; TAS:Reactome.
DR   GO; GO:0080111; P:DNA demethylation; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0006298; P:mismatch repair; IDA:UniProtKB.
DR   GO; GO:0035562; P:negative regulation of chromatin binding; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0040029; P:regulation of gene expression, epigenetic; ISS:UniProtKB.
//
ID   TDH_HUMAN               Reviewed;         230 AA.
AC   Q8IZJ6; Q8IZJ5; Q96LV6;
DE   RecName: Full=Inactive L-threonine 3-dehydrogenase, mitochondrial;
DE   Flags: Precursor;
GN   Name=TDH;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0044237; P:cellular metabolic process; IEA:InterPro.
//
ID   TDIF2_HUMAN             Reviewed;         756 AA.
AC   Q5QJE6; Q12987; Q53H59; Q5TFJ4; Q6TLI0; Q76MJ8; Q86WX9;
DE   RecName: Full=Deoxynucleotidyltransferase terminal-interacting protein 2;
DE   AltName: Full=Estrogen receptor-binding protein;
DE   AltName: Full=LPTS-interacting protein 2;
DE            Short=LPTS-RP2;
DE   AltName: Full=Terminal deoxynucleotidyltransferase-interacting factor 2;
DE            Short=TdIF2;
DE            Short=TdT-interacting factor 2;
GN   Name=DNTTIP2; Synonyms=ERBP, TDIF2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TDIF1_HUMAN             Reviewed;         329 AA.
AC   Q9H147; B2RA18; Q96DE3; Q9BQP2; Q9H148;
DE   RecName: Full=Deoxynucleotidyltransferase terminal-interacting protein 1;
DE   AltName: Full=Terminal deoxynucleotidyltransferase-interacting factor 1;
DE            Short=TdIF1;
DE            Short=TdT-interacting factor 1;
GN   Name=DNTTIP1; Synonyms=C20orf167, TDIF1;
//
ID   TDR10_HUMAN             Reviewed;         366 AA.
AC   Q5VZ19; A4FU09; B0QZ53; B4DXV4; Q3ZCP1; Q3ZCS7; Q5SXY7; Q6UXV2;
AC   Q8TCN3;
DE   RecName: Full=Tudor domain-containing protein 10;
GN   Name=TDRD10; ORFNames=UNQ9380/PRO34205;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   TDR15_HUMAN             Reviewed;        1934 AA.
AC   B5MCY1;
DE   RecName: Full=Tudor domain-containing protein 15;
GN   Name=TDRD15;
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   TDRD1_HUMAN             Reviewed;        1180 AA.
AC   Q9BXT4; A6NEN3; A6NMN2; B3KVI4; B4E2L5; D3DRC2; Q4G0Y8; Q6P518;
AC   Q9H7B3;
DE   RecName: Full=Tudor domain-containing protein 1;
DE   AltName: Full=Cancer/testis antigen 41.1;
DE            Short=CT41.1;
GN   Name=TDRD1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; ISS:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TDR12_HUMAN             Reviewed;        1177 AA.
AC   Q587J7;
DE   RecName: Full=Putative ATP-dependent RNA helicase TDRD12;
DE            EC=3.6.4.13;
DE   AltName: Full=ES cell-associated transcript 8 protein;
DE   AltName: Full=Tudor domain-containing protein 12;
GN   Name=TDRD12; Synonyms=ECAT8;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; ISS:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TDRD3_HUMAN             Reviewed;         651 AA.
AC   Q9H7E2; B2MWP9; Q53XA6; Q6P992;
DE   RecName: Full=Tudor domain-containing protein 3;
GN   Name=TDRD3;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; IDA:GOC.
//
ID   TDRD5_HUMAN             Reviewed;         981 AA.
AC   Q8NAT2; A1L4G5; B7ZLV0; Q5EBN4; Q5VTV0; Q6ZSK2;
DE   RecName: Full=Tudor domain-containing protein 5;
GN   Name=TDRD5;
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0030719; P:P granule organization; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
//
ID   TDRD6_HUMAN             Reviewed;        2096 AA.
AC   O60522; B3KWU2; F5H5M3; Q5HYB1; Q5VTS4; Q6ZMX5;
DE   RecName: Full=Tudor domain-containing protein 6;
DE   AltName: Full=Antigen NY-CO-45;
DE   AltName: Full=Cancer/testis antigen 41.2;
DE            Short=CT41.2;
GN   Name=TDRD6;
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TDRD7_HUMAN             Reviewed;        1098 AA.
AC   Q8NHU6; A6NCI6; B2RBX3; B4DG99; B4DXF7; E7EQD4; Q5VV27; Q96JT1;
AC   Q9UFF0; Q9Y2M3;
DE   RecName: Full=Tudor domain-containing protein 7;
DE   AltName: Full=PCTAIRE2-binding protein;
DE   AltName: Full=Tudor repeat associator with PCTAIRE-2;
DE            Short=Trap;
GN   Name=TDRD7; Synonyms=PCTAIRE2BP;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IMP:UniProtKB.
DR   GO; GO:0002089; P:lens morphogenesis in camera-type eye; IMP:UniProtKB.
DR   GO; GO:0010608; P:posttranscriptional regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TDRD9_HUMAN             Reviewed;        1382 AA.
AC   Q8NDG6; A1A4S7; Q6ZU54; Q8N7T3; Q8N827; Q8N9V5; Q96AS9;
DE   RecName: Full=Putative ATP-dependent RNA helicase TDRD9;
DE            EC=3.6.4.13;
DE   AltName: Full=Tudor domain-containing protein 9;
GN   Name=TDRD9; Synonyms=C14orf75;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TDRG1_HUMAN             Reviewed;         100 AA.
AC   Q3Y452;
DE   RecName: Full=Testis development-related protein 1;
GN   Name=TDRG1;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   TDRKH_HUMAN             Reviewed;         561 AA.
AC   Q9Y2W6; D3DV24; Q5SZR3; Q5SZR5; Q8N582; Q9NYV5;
DE   RecName: Full=Tudor and KH domain-containing protein;
DE   AltName: Full=Tudor domain-containing protein 2;
GN   Name=TDRKH; Synonyms=TDRD2;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043046; P:DNA methylation involved in gamete generation; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; ISS:UniProtKB.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0034587; P:piRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TDRP_HUMAN              Reviewed;         185 AA.
AC   Q86YL5; B6VF03; B9EG53;
DE   RecName: Full=Testis development-related protein;
DE   AltName: Full=Protein INM01;
GN   Name=TDRP; Synonyms=C8orf42;
DR   GO; GO:0007283; P:spermatogenesis; IDA:MGI.
//
ID   TDT_HUMAN               Reviewed;         509 AA.
AC   P04053; Q53FH1; Q5W103; Q96E50;
DE   RecName: Full=DNA nucleotidylexotransferase;
DE            EC=2.7.7.31;
DE   AltName: Full=Terminal addition enzyme;
DE   AltName: Full=Terminal deoxynucleotidyltransferase;
DE            Short=Terminal transferase;
GN   Name=DNTT; Synonyms=TDT;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003912; F:DNA nucleotidylexotransferase activity; TAS:ProtInc.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006304; P:DNA modification; IEA:UniProtKB-KW.
//
ID   TE2IP_HUMAN             Reviewed;         399 AA.
AC   Q9NYB0; B4DQN4; Q4W4Y2; Q8WYZ3; Q9NWR2;
DE   RecName: Full=Telomeric repeat-binding factor 2-interacting protein 1;
DE            Short=TERF2-interacting telomeric protein 1;
DE            Short=TRF2-interacting telomeric protein 1;
DE   AltName: Full=Dopamine receptor-interacting protein 5;
DE   AltName: Full=Repressor/activator protein 1 homolog;
DE            Short=RAP1 homolog;
DE            Short=hRap1;
GN   Name=TERF2IP; Synonyms=DRIP5, RAP1; ORFNames=PP8000;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048239; P:negative regulation of DNA recombination at telomere; ISS:UniProtKB.
DR   GO; GO:0032205; P:negative regulation of telomere maintenance; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0031848; P:protection from non-homologous end joining at telomere; IMP:BHF-UCL.
DR   GO; GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IDA:BHF-UCL.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; TAS:ProtInc.
DR   GO; GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TEAD1_HUMAN             Reviewed;         426 AA.
AC   P28347;
DE   RecName: Full=Transcriptional enhancer factor TEF-1;
DE   AltName: Full=NTEF-1;
DE   AltName: Full=Protein GT-IIC;
DE   AltName: Full=TEA domain family member 1;
DE            Short=TEAD-1;
DE   AltName: Full=Transcription factor 13;
DE            Short=TCF-13;
GN   Name=TEAD1; Synonyms=TCF13, TEF1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   TEAD2_HUMAN             Reviewed;         447 AA.
AC   Q15562; B4DTJ6; Q8NA25; Q96IG3;
DE   RecName: Full=Transcriptional enhancer factor TEF-4;
DE   AltName: Full=TEA domain family member 2;
DE            Short=TEAD-2;
GN   Name=TEAD2; Synonyms=TEF4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   TEAD4_HUMAN             Reviewed;         434 AA.
AC   Q15561; H0Y308; Q6MZR9; Q8NEV5; Q92883; Q96BK2;
DE   RecName: Full=Transcriptional enhancer factor TEF-3;
DE   AltName: Full=TEA domain family member 4;
DE            Short=TEAD-4;
DE   AltName: Full=Transcription factor 13-like 1;
DE   AltName: Full=Transcription factor RTEF-1;
GN   Name=TEAD4; Synonyms=RTEF1, TCF13L1, TEF3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   TEAD3_HUMAN             Reviewed;         435 AA.
AC   Q99594; O95910; Q5BJG7; Q8N6Y4;
DE   RecName: Full=Transcriptional enhancer factor TEF-5;
DE   AltName: Full=DTEF-1;
DE   AltName: Full=TEA domain family member 3;
DE            Short=TEAD-3;
GN   Name=TEAD3; Synonyms=TEAD5, TEF5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   TEAN2_HUMAN             Reviewed;         208 AA.
AC   Q96MN5; Q5T702; Q8N8N2;
DE   RecName: Full=Transcription elongation factor A N-terminal and central domain-containing protein 2;
GN   Name=TCEANC2; Synonyms=C1orf83;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   TEANC_HUMAN             Reviewed;         351 AA.
AC   Q8N8B7; A6NI06; B2RDM3;
DE   RecName: Full=Transcription elongation factor A N-terminal and central domain-containing protein;
DE   AltName: Full=TFIIS central domain-containing protein 1;
GN   Name=TCEANC;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
//
ID   TECT1_HUMAN             Reviewed;         587 AA.
AC   Q2MV58; A8MX11; Q49A60; Q6P5X1; Q6UXW2; Q8NAE9; Q96N72; Q9H798;
DE   RecName: Full=Tectonic-1;
DE   Flags: Precursor;
GN   Name=TCTN1; Synonyms=TECT1; ORFNames=UNQ9369/PRO34160;
DR   GO; GO:0021956; P:central nervous system interneuron axonogenesis; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0001841; P:neural tube formation; IEA:Ensembl.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0021523; P:somatic motor neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
//
ID   TEBP_HUMAN              Reviewed;         160 AA.
AC   Q15185; A8K7D0; Q8WU70;
DE   RecName: Full=Prostaglandin E synthase 3;
DE            EC=5.3.99.3;
DE   AltName: Full=Cytosolic prostaglandin E2 synthase;
DE            Short=cPGES;
DE   AltName: Full=Hsp90 co-chaperone;
DE   AltName: Full=Progesterone receptor complex p23;
DE   AltName: Full=Telomerase-binding protein p23;
GN   Name=PTGES3; Synonyms=P23, TEBP;
DR   GO; GO:0050220; F:prostaglandin-E synthase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003720; F:telomerase activity; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0070389; P:chaperone cofactor-dependent protein refolding; IDA:UniProtKB.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0001516; P:prostaglandin biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006278; P:RNA-dependent DNA replication; IDA:GOC.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:UniProtKB.
//
ID   TECR_HUMAN              Reviewed;         308 AA.
AC   Q9NZ01; B2RD55; O75350; Q6IBB2; Q9BWK3; Q9Y6P0;
DE   RecName: Full=Very-long-chain enoyl-CoA reductase;
DE            EC=1.3.1.93;
DE   AltName: Full=Synaptic glycoprotein SC2;
DE   AltName: Full=Trans-2,3-enoyl-CoA reductase;
DE            Short=TER;
GN   Name=TECR; Synonyms=GPSN2, SC2;
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0030497; P:fatty acid elongation; IDA:UniProtKB.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
DR   GO; GO:0042761; P:very long-chain fatty acid biosynthetic process; IDA:UniProtKB.
//
ID   TECT3_HUMAN             Reviewed;         607 AA.
AC   Q6NUS6; A6NIC8; B0QZ90; B4DR81; Q6P7P3; Q6UW27; Q6ZQQ0; Q8N7K1;
AC   Q8NBQ0; Q96GF7; Q9Y3U1;
DE   RecName: Full=Tectonic-3;
DE   Flags: Precursor;
GN   Name=TCTN3; Synonyms=C10orf61, TECT3;
GN   ORFNames=PSEC0041, UNQ1881/PRO4324;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB.
//
ID   TECT2_HUMAN             Reviewed;         697 AA.
AC   Q96GX1; A8K7Y8; B3KPW5; Q9H966;
DE   RecName: Full=Tectonic-2;
DE   Flags: Precursor;
GN   Name=TCTN2; Synonyms=C12orf38, TECT2;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   TECRL_HUMAN             Reviewed;         363 AA.
AC   Q5HYJ1;
DE   RecName: Full=Trans-2,3-enoyl-CoA reductase-like;
DE            EC=1.3.1.-;
DE   AltName: Full=Steroid 5-alpha-reductase 2-like 2 protein;
GN   Name=TECRL; Synonyms=SRD5A2L2;
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
//
ID   TECTA_HUMAN             Reviewed;        2155 AA.
AC   O75443;
DE   RecName: Full=Alpha-tectorin;
DE   Flags: Precursor;
GN   Name=TECTA;
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   TECTB_HUMAN             Reviewed;         329 AA.
AC   Q96PL2; Q5VW53;
DE   RecName: Full=Beta-tectorin;
DE   Flags: Precursor;
GN   Name=TECTB;
//
ID   TEC_HUMAN               Reviewed;         631 AA.
AC   P42680; B7ZKZ6; Q3MIS5;
DE   RecName: Full=Tyrosine-protein kinase Tec;
DE            EC=2.7.10.2;
GN   Name=TEC; Synonyms=PSCTK4;
DR   GuidetoPHARMACOLOGY; 2238; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0010543; P:regulation of platelet activation; IDA:UniProtKB.
DR   GO; GO:0042246; P:tissue regeneration; IEA:Ensembl.
//
ID   TEFF1_HUMAN             Reviewed;         380 AA.
AC   Q8IYR6; Q13086; Q8N3T8;
DE   RecName: Full=Tomoregulin-1;
DE            Short=TR-1;
DE   AltName: Full=H7365;
DE   AltName: Full=Transmembrane protein with EGF-like and one follistatin-like domain;
DE   Flags: Precursor;
GN   Name=TMEFF1; Synonyms=C9orf2;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   TEDM1_HUMAN             Reviewed;         273 AA.
AC   Q5T9Z0; Q8IVJ0;
DE   RecName: Full=Transmembrane epididymal protein 1;
DE   AltName: Full=Human epididymis-specific protein 9;
DE            Short=He9;
GN   Name=TEDDM1; Synonyms=HE9;
//
ID   TEFF2_HUMAN             Reviewed;         374 AA.
AC   Q9UIK5; Q2FA44; Q4ZFW4; Q53H90; Q53RE1; Q8N2R5; Q9NR15; Q9NSS5;
AC   Q9P2Y9; Q9UK65;
DE   RecName: Full=Tomoregulin-2;
DE            Short=TR-2;
DE   AltName: Full=Hyperplastic polyposis protein 1;
DE   AltName: Full=Transmembrane protein with EGF-like and two follistatin-like domains;
DE   Flags: Precursor;
GN   Name=TMEFF2; Synonyms=HPP1, TENB2, TPEF; ORFNames=UNQ178/PRO204;
//
ID   TEFM_HUMAN              Reviewed;         360 AA.
AC   Q96QE5; E1P655; Q6GPG5; Q6PJ19; Q96H04; Q9H5Z9;
DE   RecName: Full=Transcription elongation factor, mitochondrial;
DE   Flags: Precursor;
GN   Name=TEFM; Synonyms=C17orf42;
DR   GO; GO:0030337; F:DNA polymerase processivity factor activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006259; P:DNA metabolic process; IDA:GOC.
DR   GO; GO:0006119; P:oxidative phosphorylation; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IMP:UniProtKB.
//
ID   TEF_HUMAN               Reviewed;         303 AA.
AC   Q10587; B0QYS8; B2RC22; Q15729; Q7Z3J7; Q8IU94; Q96TG4;
DE   RecName: Full=Thyrotroph embryonic factor;
GN   Name=TEF; Synonyms=KIAA1655;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TEKT1_HUMAN             Reviewed;         418 AA.
AC   Q969V4; D3DTM7;
DE   RecName: Full=Tektin-1;
GN   Name=TEKT1;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   TEKT2_HUMAN             Reviewed;         430 AA.
AC   Q9UIF3; A6NIS6; O60638;
DE   RecName: Full=Tektin-2;
DE   AltName: Full=Tektin-t;
DE   AltName: Full=Testicular tektin;
DE   AltName: Full=Testicular tektin B1-like protein;
DE            Short=TEKTB1;
DE            Short=Tektin-B1;
GN   Name=TEKT2;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0001539; P:cilium or flagellum-dependent cell motility; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
//
ID   TEKT4_HUMAN             Reviewed;         435 AA.
AC   Q8WW24;
DE   RecName: Full=Tektin-4;
GN   Name=TEKT4;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   TEKT3_HUMAN             Reviewed;         490 AA.
AC   Q9BXF9; B2RAS7; D3DTT0; Q8N5R5; Q96M48;
DE   RecName: Full=Tektin-3;
GN   Name=TEKT3;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   TEKT5_HUMAN             Reviewed;         485 AA.
AC   Q96M29; A1L3Z3;
DE   RecName: Full=Tektin-5;
GN   Name=TEKT5;
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.
//
ID   TELO2_HUMAN             Reviewed;         837 AA.
AC   Q9Y4R8; D3DU73; O75168; Q7LDV4; Q9BR21;
DE   RecName: Full=Telomere length regulation protein TEL2 homolog;
DE   AltName: Full=Protein clk-2 homolog;
DE            Short=hCLK2;
GN   Name=TELO2; Synonyms=KIAA0683;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:MGI.
DR   GO; GO:0032006; P:regulation of TOR signaling; IMP:UniProtKB.
//
ID   TELT_HUMAN              Reviewed;         167 AA.
AC   O15273; Q96L27;
DE   RecName: Full=Telethonin;
DE   AltName: Full=Titin cap protein;
GN   Name=TCAP;
DR   GO; GO:0051373; F:FATZ binding; IPI:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; IDA:BHF-UCL.
DR   GO; GO:0008307; F:structural constituent of muscle; IMP:BHF-UCL.
DR   GO; GO:0031432; F:titin binding; IPI:BHF-UCL.
DR   GO; GO:0070080; F:titin Z domain binding; IPI:BHF-UCL.
DR   GO; GO:0007512; P:adult heart development; IMP:BHF-UCL.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.
DR   GO; GO:0003300; P:cardiac muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:0014898; P:cardiac muscle hypertrophy in response to stress; IMP:BHF-UCL.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.
DR   GO; GO:0050982; P:detection of mechanical stimulus; TAS:BHF-UCL.
DR   GO; GO:0035995; P:detection of muscle stretch; IMP:BHF-UCL.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0030916; P:otic vesicle formation; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0035994; P:response to muscle stretch; TAS:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IMP:BHF-UCL.
DR   GO; GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.
DR   GO; GO:0003009; P:skeletal muscle contraction; IEP:BHF-UCL.
DR   GO; GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.
DR   GO; GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
//
ID   TEN1L_HUMAN             Reviewed;         123 AA.
AC   Q86WV5; I3L0C7;
DE   RecName: Full=CST complex subunit TEN1;
DE   AltName: Full=Protein telomeric pathways with STN1 homolog;
DE   AltName: Full=Telomere length regulation protein TEN1 homolog;
GN   Name=TEN1; Synonyms=C17orf106;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   TEN1_HUMAN              Reviewed;        2725 AA.
AC   Q9UKZ4; B2RTR5; Q5JZ17;
DE   RecName: Full=Teneurin-1;
DE            Short=Ten-1;
DE   AltName: Full=Protein Odd Oz/ten-m homolog 1;
DE   AltName: Full=Tenascin-M1;
DE            Short=Ten-m1;
DE   AltName: Full=Teneurin transmembrane protein 1;
DE   Contains:
DE     RecName: Full=Ten-1 intracellular domain;
DE              Short=IDten-1;
DE              Short=Ten-1 ICD;
DE   Contains:
DE     RecName: Full=Teneurin C-terminal-associated peptide;
DE              Short=TCPA-1;
DE     AltName: Full=Ten-1 extracellular domain;
DE              Short=Ten-1 ECD;
GN   Name=TENM1; Synonyms=ODZ1, TNM1;
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; ISS:UniProtKB.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TEN2_HUMAN              Reviewed;        2774 AA.
AC   Q9NT68; Q9ULU2;
DE   RecName: Full=Teneurin-2;
DE            Short=Ten-2;
DE   AltName: Full=Protein Odd Oz/ten-m homolog 2;
DE   AltName: Full=Tenascin-M2;
DE            Short=Ten-m2;
DE   AltName: Full=Teneurin transmembrane protein 2;
DE   Contains:
DE     RecName: Full=Ten-2, soluble form;
DE   Contains:
DE     RecName: Full=Ten-2 intracellular domain;
DE              Short=Ten-2 ICD;
GN   Name=TENM2; Synonyms=KIAA1127, ODZ2, TNM2;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IDA:UniProtKB.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IDA:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TEN3_HUMAN              Reviewed;        2699 AA.
AC   Q9P273; Q5XUL9; Q96SY2; Q9NV77; Q9NVW1; Q9NZJ2;
DE   RecName: Full=Teneurin-3;
DE            Short=Ten-3;
DE   AltName: Full=Protein Odd Oz/ten-m homolog 3;
DE   AltName: Full=Tenascin-M3;
DE            Short=Ten-m3;
DE   AltName: Full=Teneurin transmembrane protein 3;
GN   Name=TENM3; Synonyms=KIAA1455, ODZ3, TNM3;
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0007156; P:homophilic cell adhesion; ISS:UniProtKB.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   TEN4_HUMAN              Reviewed;        2769 AA.
AC   Q6N022; A6ND26; Q7Z3C7; Q96MS6; Q9P2P4; Q9Y4S2;
DE   RecName: Full=Teneurin-4;
DE            Short=Ten-4;
DE   AltName: Full=Protein Odd Oz/ten-m homolog 4;
DE   AltName: Full=Tenascin-M4;
DE            Short=Ten-m4;
DE   AltName: Full=Teneurin transmembrane protein 4;
GN   Name=TENM4; Synonyms=KIAA1302, ODZ4, TNM4;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0060912; P:cardiac cell fate specification; IEA:Ensembl.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0032289; P:central nervous system myelin formation; ISS:UniProtKB.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0048666; P:neuron development; IEA:InterPro.
DR   GO; GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.
DR   GO; GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   TENA_HUMAN              Reviewed;        2201 AA.
AC   P24821; C9IYT7; C9J575; C9J6D9; C9J848; Q14583; Q15567; Q5T7S3;
DE   RecName: Full=Tenascin;
DE            Short=TN;
DE   AltName: Full=Cytotactin;
DE   AltName: Full=GMEM;
DE   AltName: Full=GP 150-225;
DE   AltName: Full=Glioma-associated-extracellular matrix antigen;
DE   AltName: Full=Hexabrachion;
DE   AltName: Full=JI;
DE   AltName: Full=Myotendinous antigen;
DE   AltName: Full=Neuronectin;
DE   AltName: Full=Tenascin-C;
DE            Short=TN-C;
DE   Flags: Precursor;
GN   Name=TNC; Synonyms=HXB;
DR   GO; GO:0045545; F:syndecan binding; IPI:MGI.
DR   GO; GO:0060447; P:bud outgrowth involved in lung branching; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0071799; P:cellular response to prostaglandin D stimulus; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0071305; P:cellular response to vitamin D; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060739; P:mesenchymal-epithelial cell signaling involved in prostate gland development; IEA:Ensembl.
DR   GO; GO:0007162; P:negative regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0014012; P:peripheral nervous system axon regeneration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060740; P:prostate gland epithelium morphogenesis; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0071774; P:response to fibroblast growth factor; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEP:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   TENC1_HUMAN             Reviewed;        1409 AA.
AC   Q63HR2; A2VDF2; A2VDF3; A2VDI8; A5PKY4; Q2NL80; Q76MW6; Q7Z5T9;
AC   Q8NFF9; Q8NFG0; Q96P25; Q9NT29; Q9UPS7;
DE   RecName: Full=Tensin-like C1 domain-containing phosphatase;
DE            EC=3.1.3.-;
DE   AltName: Full=C1 domain-containing phosphatase and tensin homolog;
DE            Short=C1-TEN;
DE   AltName: Full=Tensin-2;
GN   Name=TENC1; Synonyms=KIAA1075, TNS2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019725; P:cellular homeostasis; IEA:Ensembl.
DR   GO; GO:0032963; P:collagen metabolic process; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048871; P:multicellular organismal homeostasis; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
//
ID   TENN_HUMAN              Reviewed;        1299 AA.
AC   Q9UQP3; B9EGP3; Q5R360;
DE   RecName: Full=Tenascin-N;
DE            Short=TN-N;
DE   Flags: Precursor;
GN   Name=TNN;
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0016049; P:cell growth; ISS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
//
ID   TENR_HUMAN              Reviewed;        1358 AA.
AC   Q92752; C9J563; Q15568; Q5R3G0;
DE   RecName: Full=Tenascin-R;
DE            Short=TN-R;
DE   AltName: Full=Janusin;
DE   AltName: Full=Restrictin;
DE   Flags: Precursor;
GN   Name=TNR;
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; NAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0035641; P:locomotory exploration behavior; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0048692; P:negative regulation of axon extension involved in regeneration; IEA:Ensembl.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0050805; P:negative regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; IEA:Ensembl.
DR   GO; GO:0007158; P:neuron cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0051971; P:positive regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0022029; P:telencephalon cell migration; IEA:Ensembl.
//
ID   TENS1_HUMAN             Reviewed;        1735 AA.
AC   Q9HBL0; Q4ZG71;
DE   RecName: Full=Tensin-1;
GN   Name=TNS1; Synonyms=TNS;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007044; P:cell-substrate junction assembly; IEA:Ensembl.
DR   GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
//
ID   TENS3_HUMAN             Reviewed;        1445 AA.
AC   Q68CZ2; B2RNV1; Q6IPQ2; Q8IZW7; Q8NAD0; Q96PE0; Q96S48;
DE   RecName: Full=Tensin-3;
DE   AltName: Full=Tensin-like SH2 domain-containing protein 1;
DE   AltName: Full=Tumor endothelial marker 6;
GN   Name=TNS3; Synonyms=TEM6, TENS1, TPP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
//
ID   TENS4_HUMAN             Reviewed;         715 AA.
AC   Q8IZW8; A6NMJ7; Q71RB7; Q8WV64; Q96JV4;
DE   RecName: Full=Tensin-4;
DE   AltName: Full=C-terminal tensin-like protein;
DE   Flags: Precursor;
GN   Name=TNS4; Synonyms=CTEN; ORFNames=PP14434;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008104; P:protein localization; IDA:UniProtKB.
//
ID   TENXA_HUMAN             Reviewed;         311 AA.
AC   Q16473;
DE   RecName: Full=Putative tenascin-XA;
DE            Short=TN-XA;
GN   Name=TNXA; Synonyms=XA;
//
ID   TENX_HUMAN              Reviewed;        4289 AA.
AC   P22105; P78530; P78531; Q08424; Q08AM0; Q08AM1; Q59GU7; Q5SQD3;
AC   Q5ST74; Q7L8Q4; Q8N4R1; Q9NPK9; Q9UC10; Q9UC11; Q9UC12; Q9UC13;
AC   Q9UMG7;
DE   RecName: Full=Tenascin-X;
DE            Short=TN-X;
DE   AltName: Full=Hexabrachion-like protein;
DE   Flags: Precursor;
GN   Name=TNXB; Synonyms=HXBL, TNX, TNXB1, TNXB2, XB;
DR   GO; GO:0008201; F:heparin binding; ISS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; ISS:UniProtKB.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0030199; P:collagen fibril organization; IEA:Ensembl.
DR   GO; GO:0032963; P:collagen metabolic process; IMP:UniProtKB.
DR   GO; GO:0048251; P:elastic fiber assembly; IMP:UniProtKB.
DR   GO; GO:0043206; P:extracellular fibril organization; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0043506; P:regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:Ensembl.
//
ID   TEP1_HUMAN              Reviewed;        2627 AA.
AC   Q99973; A0AUV9;
DE   RecName: Full=Telomerase protein component 1;
DE   AltName: Full=Telomerase-associated protein 1;
DE            Short=Telomerase protein 1;
DE   AltName: Full=p240;
DE   AltName: Full=p80 telomerase homolog;
GN   Name=TEP1; Synonyms=TLP1, TP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0006278; P:RNA-dependent DNA replication; IDA:GOC.
DR   GO; GO:0000722; P:telomere maintenance via recombination; IDA:UniProtKB.
//
ID   TEPP_HUMAN              Reviewed;         271 AA.
AC   Q6URK8; Q6URK7;
DE   RecName: Full=Testis, prostate and placenta-expressed protein;
DE   Flags: Precursor;
GN   Name=TEPP;
//
ID   TERA_HUMAN              Reviewed;         806 AA.
AC   P55072; B2R5T8; Q0V924; Q2TAI5; Q969G7; Q9UCD5;
DE   RecName: Full=Transitional endoplasmic reticulum ATPase;
DE            Short=TER ATPase;
DE            EC=3.6.4.6;
DE   AltName: Full=15S Mg(2+)-ATPase p97 subunit;
DE   AltName: Full=Valosin-containing protein;
DE            Short=VCP;
GN   Name=VCP;
DR   GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; TAS:UniProtKB.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0070842; P:aggresome assembly; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0045184; P:establishment of protein localization; TAS:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0030970; P:retrograde protein transport, ER to cytosol; IDA:UniProtKB.
DR   GO; GO:0019985; P:translesion synthesis; IMP:UniProtKB.
//
ID   TERB1_HUMAN             Reviewed;         727 AA.
AC   Q8NA31; A0AUW1;
DE   RecName: Full=Telomere repeats-binding bouquet formation protein 1;
DE   AltName: Full=Coiled-coil domain-containing protein 79;
GN   Name=CCDC79; Synonyms=TERB1;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0045141; P:meiotic telomere clustering; ISS:UniProtKB.
DR   GO; GO:0007129; P:synapsis; ISS:UniProtKB.
//
ID   TERF1_HUMAN             Reviewed;         439 AA.
AC   P54274; A7XP29; Q15553; Q8NHT6; Q93029;
DE   RecName: Full=Telomeric repeat-binding factor 1;
DE   AltName: Full=NIMA-interacting protein 2;
DE   AltName: Full=TTAGGG repeat-binding factor 1;
DE   AltName: Full=Telomeric protein Pin2/TRF1;
GN   Name=TERF1; Synonyms=PIN2, TRBF1, TRF, TRF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:BHF-UCL.
DR   GO; GO:0003691; F:double-stranded telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0001309; P:age-dependent telomere shortening; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IDA:BHF-UCL.
DR   GO; GO:0051974; P:negative regulation of telomerase activity; IGI:BHF-UCL.
DR   GO; GO:0032214; P:negative regulation of telomere maintenance via semi-conservative replication; NAS:BHF-UCL.
DR   GO; GO:0032211; P:negative regulation of telomere maintenance via telomerase; IGI:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0031116; P:positive regulation of microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0045840; P:positive regulation of mitosis; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; IMP:UniProtKB.
DR   GO; GO:0010834; P:telomere maintenance via telomere shortening; IMP:BHF-UCL.
//
ID   TERF2_HUMAN             Reviewed;         542 AA.
AC   Q15554;
DE   RecName: Full=Telomeric repeat-binding factor 2;
DE   AltName: Full=TTAGGG repeat-binding factor 2;
DE   AltName: Full=Telomeric DNA-binding protein;
GN   Name=TERF2; Synonyms=TRBF2, TRF2;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003691; F:double-stranded telomeric DNA binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0001309; P:age-dependent telomere shortening; NAS:BHF-UCL.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0090398; P:cellular senescence; NAS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0032205; P:negative regulation of telomere maintenance; IDA:UniProtKB.
DR   GO; GO:0032214; P:negative regulation of telomere maintenance via semi-conservative replication; NAS:BHF-UCL.
DR   GO; GO:0032206; P:positive regulation of telomere maintenance; IEA:Ensembl.
DR   GO; GO:0031848; P:protection from non-homologous end joining at telomere; IMP:BHF-UCL.
DR   GO; GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.
DR   GO; GO:0016233; P:telomere capping; IMP:BHF-UCL.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; IC:BHF-UCL.
DR   GO; GO:0010834; P:telomere maintenance via telomere shortening; IMP:BHF-UCL.
DR   GO; GO:0031627; P:telomeric loop formation; IDA:BHF-UCL.
//
ID   TERT_HUMAN              Reviewed;        1132 AA.
AC   O14746; O14783; Q2XS35; Q8N6C3; Q8NG38; Q8NG46;
DE   RecName: Full=Telomerase reverse transcriptase;
DE            EC=2.7.7.49;
DE   AltName: Full=HEST2;
DE   AltName: Full=Telomerase catalytic subunit;
DE   AltName: Full=Telomerase-associated protein 2;
DE            Short=TP2;
GN   Name=TERT; Synonyms=EST2, TCS1, TRT;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0003720; F:telomerase activity; IDA:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; TAS:ProtInc.
DR   GO; GO:0070034; F:telomeric RNA binding; IDA:BHF-UCL.
DR   GO; GO:0003721; F:telomeric template RNA reverse transcriptase activity; TAS:UniProtKB.
DR   GO; GO:0022616; P:DNA strand elongation; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:BHF-UCL.
DR   GO; GO:0090399; P:replicative senescence; IMP:BHF-UCL.
DR   GO; GO:0032203; P:telomere formation via telomerase; IDA:BHF-UCL.
DR   GO; GO:0000723; P:telomere maintenance; TAS:UniProtKB.
DR   GO; GO:0007004; P:telomere maintenance via telomerase; IMP:BHF-UCL.
//
ID   TESK1_HUMAN             Reviewed;         626 AA.
AC   Q15569; Q8IXZ8;
DE   RecName: Full=Dual specificity testis-specific protein kinase 1;
DE            EC=2.7.12.1;
DE   AltName: Full=Testicular protein kinase 1;
GN   Name=TESK1;
DR   GuidetoPHARMACOLOGY; 2239; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   TESK2_HUMAN             Reviewed;         571 AA.
AC   Q96S53; Q5T422; Q5T423; Q8N520; Q9Y3Q6;
DE   RecName: Full=Dual specificity testis-specific protein kinase 2;
DE            EC=2.7.12.1;
DE   AltName: Full=Testicular protein kinase 2;
GN   Name=TESK2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TESP1_HUMAN             Reviewed;         521 AA.
AC   A2RU30; B4DPM3; B4E048; B7Z9K7; O94849; Q4G0P2; Q9P0C4;
DE   RecName: Full=Protein TESPA1;
DE   AltName: Full=Thymocyte-expressed positive selection-associated protein 1;
GN   Name=TESPA1; Synonyms=KIAA0748; ORFNames=HSPC257;
DR   GO; GO:0010387; P:COP9 signalosome assembly; ISS:UniProtKB.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:UniProtKB.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; ISS:UniProtKB.
//
ID   TEST_HUMAN              Reviewed;         314 AA.
AC   Q9Y6M0; Q9NS34; Q9P2V6;
DE   RecName: Full=Testisin;
DE            EC=3.4.21.-;
DE   AltName: Full=Eosinophil serine protease 1;
DE            Short=ESP-1;
DE   AltName: Full=Serine protease 21;
DE   Flags: Precursor;
GN   Name=PRSS21; Synonyms=ESP1, TEST1; ORFNames=UNQ266/PRO303;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
//
ID   TES_HUMAN               Reviewed;         421 AA.
AC   Q9UGI8; A4D0U6; Q9GZQ1; Q9HAJ9;
DE   RecName: Full=Testin;
DE   AltName: Full=TESS;
GN   Name=TES;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
//
ID   TET1_HUMAN              Reviewed;        2136 AA.
AC   Q8NFU7; Q5VUP7; Q7Z6B6; Q8TCR1; Q9C0I7;
DE   RecName: Full=Methylcytosine dioxygenase TET1;
DE            EC=1.14.11.n2;
DE   AltName: Full=CXXC-type zinc finger protein 6;
DE   AltName: Full=Leukemia-associated protein with a CXXC domain;
DE   AltName: Full=Ten-eleven translocation 1 gene protein;
GN   Name=TET1; Synonyms=CXXC6, KIAA1676, LCX;
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0070579; F:methylcytosine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0043566; F:structure-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0080111; P:DNA demethylation; IMP:UniProtKB.
DR   GO; GO:0001826; P:inner cell mass cell differentiation; ISS:UniProtKB.
DR   GO; GO:0090310; P:negative regulation of methylation-dependent chromatin silencing; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; ISS:UniProtKB.
DR   GO; GO:0044030; P:regulation of DNA methylation; IEA:Ensembl.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TET2_HUMAN              Reviewed;        2002 AA.
AC   Q6N021; B5MDU0; Q2TB88; Q3LIB8; Q96JX5; Q9HCM6; Q9NXW0;
DE   RecName: Full=Methylcytosine dioxygenase TET2;
DE            EC=1.14.11.n2;
GN   Name=TET2; Synonyms=KIAA1546; ORFNames=Nbla00191;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008198; F:ferrous iron binding; IDA:UniProtKB.
DR   GO; GO:0070579; F:methylcytosine dioxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006211; P:5-methylcytosine catabolic process; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0080111; P:DNA demethylation; IDA:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0030099; P:myeloid cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IDA:UniProtKB.
//
ID   TET3_HUMAN              Reviewed;        1660 AA.
AC   O43151; A6NEI3; Q86Z24; Q8TBM9;
DE   RecName: Full=Methylcytosine dioxygenase TET3;
DE            EC=1.14.11.n2;
GN   Name=TET3; Synonyms=KIAA0401;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0070579; F:methylcytosine dioxygenase activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0080111; P:DNA demethylation; ISS:UniProtKB.
DR   GO; GO:0044727; P:DNA demethylation of male pronucleus; ISS:UniProtKB.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IMP:UniProtKB.
//
ID   TETN_HUMAN              Reviewed;         202 AA.
AC   P05452; Q6FGX6;
DE   RecName: Full=Tetranectin;
DE            Short=TN;
DE   AltName: Full=C-type lectin domain family 3 member B;
DE   AltName: Full=Plasminogen kringle 4-binding protein;
DE   Flags: Precursor;
GN   Name=CLEC3B; Synonyms=TNA;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0036143; F:kringle domain binding; IPI:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; IDA:UniProtKB.
DR   GO; GO:0071310; P:cellular response to organic substance; IEP:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEP:UniProtKB.
DR   GO; GO:0010756; P:positive regulation of plasminogen activation; ISS:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
//
ID   TEX10_HUMAN             Reviewed;         929 AA.
AC   Q9NXF1; B4DYV2; Q5T722; Q5T723; Q8NCN8; Q8TDY0;
DE   RecName: Full=Testis-expressed sequence 10 protein;
GN   Name=TEX10; ORFNames=L18, Nbla10363;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TEX11_HUMAN             Reviewed;         940 AA.
AC   Q8IYF3; A8K8V6; Q5JQQ8; Q96LZ4; Q96M47; Q9BXU6;
DE   RecName: Full=Testis-expressed sequence 11 protein;
GN   Name=TEX11;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051026; P:chiasma assembly; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0007060; P:male meiosis chromosome segregation; IEA:Ensembl.
DR   GO; GO:0006311; P:meiotic gene conversion; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0007131; P:reciprocal meiotic recombination; ISS:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IEA:Ensembl.
DR   GO; GO:0007130; P:synaptonemal complex assembly; IEA:Ensembl.
//
ID   TEX12_HUMAN             Reviewed;         123 AA.
AC   Q9BXU0; A6NDL9; B0YIX3;
DE   RecName: Full=Testis-expressed sequence 12 protein;
GN   Name=TEX12;
//
ID   TEX14_HUMAN             Reviewed;        1497 AA.
AC   Q8IWB6; A6NH19; Q7RTP3; Q8ND97; Q9BXT9;
DE   RecName: Full=Inactive serine/threonine-protein kinase TEX14;
DE   AltName: Full=Protein kinase-like protein SgK307;
DE   AltName: Full=Sugen kinase 307;
DE   AltName: Full=Testis-expressed sequence 14;
DE   AltName: Full=Testis-expressed sequence 14 protein;
GN   Name=TEX14; Synonyms=SGK307;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; ISS:UniProtKB.
DR   GO; GO:0043063; P:intercellular bridge organization; ISS:UniProtKB.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0051306; P:mitotic sister chromatid separation; ISS:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; ISS:UniProtKB.
DR   GO; GO:0032466; P:negative regulation of cytokinesis; IEA:Ensembl.
DR   GO; GO:0032091; P:negative regulation of protein binding; IEA:Ensembl.
//
ID   TEX15_HUMAN             Reviewed;        2789 AA.
AC   Q9BXT5;
DE   RecName: Full=Testis-expressed sequence 15 protein;
DE   AltName: Full=Cancer/testis antigen 42;
DE            Short=CT42;
GN   Name=TEX15;
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0007140; P:male meiosis; IEA:Ensembl.
DR   GO; GO:0034502; P:protein localization to chromosome; IEA:Ensembl.
DR   GO; GO:0010569; P:regulation of double-strand break repair via homologous recombination; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0007130; P:synaptonemal complex assembly; IEA:Ensembl.
//
ID   TEX19_HUMAN             Reviewed;         164 AA.
AC   Q8NA77;
DE   RecName: Full=Testis-expressed sequence 19 protein;
GN   Name=TEX19;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TEX22_HUMAN             Reviewed;         150 AA.
AC   C9J3V5;
DE   RecName: Full=Testis-expressed sequence 22 protein;
GN   Name=TEX22;
//
ID   TEX26_HUMAN             Reviewed;         289 AA.
AC   Q8N6G2;
DE   RecName: Full=Testis-expressed sequence 26 protein;
GN   Name=TEX26; Synonyms=C13orf26;
//
ID   TEX28_HUMAN             Reviewed;         410 AA.
AC   O15482; B1B1E8; D3DWW5;
DE   RecName: Full=Testis-specific protein TEX28;
GN   Name=TEX28; Synonyms=CXorf2;
GN   and
GN   Name=TEX28P1;
GN   and
GN   Name=TEX28P2;
//
ID   TEX29_HUMAN             Reviewed;         151 AA.
AC   Q8N6K0;
DE   RecName: Full=Testis-expressed sequence 29 protein;
GN   Name=TEX29; Synonyms=C13orf16;
//
ID   TEX2_HUMAN              Reviewed;        1127 AA.
AC   Q8IWB9; Q6AHZ5; Q8N3L0; Q9C0C5;
DE   RecName: Full=Testis-expressed sequence 2 protein;
DE   AltName: Full=Transmembrane protein 96;
GN   Name=TEX2; Synonyms=KIAA1738, TMEM96;
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0006665; P:sphingolipid metabolic process; NAS:UniProtKB.
//
ID   TEX30_HUMAN             Reviewed;         227 AA.
AC   Q5JUR7; Q96KZ8;
DE   RecName: Full=Testis-expressed sequence 30 protein;
GN   Name=TEX30; Synonyms=C13orf27;
//
ID   TEX35_HUMAN             Reviewed;         233 AA.
AC   Q5T0J7; Q5T0J8; Q5T0J9; Q8IYU6; Q8N7Z1; Q8NA15; Q9H0Q7;
DE   RecName: Full=Testis-expressed sequence 35 protein;
GN   Name=Tex35; Synonyms=C1orf49;
//
ID   TEX33_HUMAN             Reviewed;         280 AA.
AC   O43247; B1AH46; Q6ICF2; Q8IVQ2; Q9Y4V8;
DE   RecName: Full=Testis-expressed sequence 33 protein;
GN   Name=TEX33; Synonyms=C22orf33, EAN57;
//
ID   TEX36_HUMAN             Reviewed;         186 AA.
AC   Q5VZQ5; Q0P5T8;
DE   RecName: Full=Testis-expressed sequence 36 protein;
GN   Name=TEX36; Synonyms=C10orf122;
//
ID   TEX37_HUMAN             Reviewed;         180 AA.
AC   Q96LM6;
DE   RecName: Full=Testis-expressed sequence 37 protein;
DE   AltName: Full=Testis-specific conserved protein of 21 kDa;
GN   Name=TEX37; Synonyms=C2orf51, TSC21;
//
ID   TEX38_HUMAN             Reviewed;         206 AA.
AC   Q6PEX7; A1A4F8;
DE   RecName: Full=Testis-expressed sequence 38 protein;
DE   AltName: Full=ATPAF1 antisense RNA 1;
DE   AltName: Full=ATPAF1 antisense gene protein 1;
GN   Name=TEX38; Synonyms=ATPAF1-AS1, C1orf223;
//
ID   TEX40_HUMAN             Reviewed;         200 AA.
AC   Q9NTU4;
DE   RecName: Full=Testis-expressed sequence 40 protein;
GN   Name=TEX40; Synonyms=C11orf20;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007140; P:male meiosis; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TEX43_HUMAN             Reviewed;         134 AA.
AC   Q6ZNM6;
DE   RecName: Full=Testis-expressed sequence 43 protein;
GN   Name=TEX43; Synonyms=C5orf48;
//
ID   TEX9_HUMAN              Reviewed;         391 AA.
AC   Q8N6V9;
DE   RecName: Full=Testis-expressed sequence 9 protein;
GN   Name=TEX9;
//
ID   TF2AA_HUMAN             Reviewed;         376 AA.
AC   P52655; Q3KNQ9;
DE   RecName: Full=Transcription initiation factor IIA subunit 1;
DE   AltName: Full=General transcription factor IIA subunit 1;
DE   AltName: Full=TFIIAL;
DE   AltName: Full=Transcription initiation factor TFIIA 42 kDa subunit;
DE            Short=TFIIA-42;
DE   Contains:
DE     RecName: Full=Transcription initiation factor IIA alpha chain;
DE     AltName: Full=TFIIA p35 subunit;
DE   Contains:
DE     RecName: Full=Transcription initiation factor IIA beta chain;
DE     AltName: Full=TFIIA p19 subunit;
GN   Name=GTF2A1; Synonyms=TF2A1;
DR   GO; GO:0003677; F:DNA binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0017025; F:TBP-class protein binding; IPI:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TF2AY_HUMAN             Reviewed;         478 AA.
AC   Q9UNN4; B4DY14; Q53FD9; Q5D050;
DE   RecName: Full=TFIIA-alpha and beta-like factor;
DE   AltName: Full=General transcription factor II A, 1-like factor;
GN   Name=GTF2A1L; Synonyms=ALF, GTF2A1LF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro.
//
ID   TF2B_HUMAN              Reviewed;         316 AA.
AC   Q00403; A8K1A7; Q5JS30;
DE   RecName: Full=Transcription initiation factor IIB;
DE   AltName: Full=General transcription factor TFIIB;
DE   AltName: Full=S300-II;
GN   Name=GTF2B; Synonyms=TF2B, TFIIB;
DR   GO; GO:0001047; F:core promoter binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TF2H1_HUMAN             Reviewed;         548 AA.
AC   P32780; D3DQY2; Q6I9Y7; Q9H5K5; Q9NQD9;
DE   RecName: Full=General transcription factor IIH subunit 1;
DE   AltName: Full=Basic transcription factor 2 62 kDa subunit;
DE            Short=BTF2 p62;
DE   AltName: Full=General transcription factor IIH polypeptide 1;
DE   AltName: Full=TFIIH basal transcription factor complex p62 subunit;
GN   Name=GTF2H1; Synonyms=BTF2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TF2H2_HUMAN             Reviewed;         395 AA.
AC   Q13888; Q15570; Q15571; Q9BS41;
DE   RecName: Full=General transcription factor IIH subunit 2;
DE   AltName: Full=Basic transcription factor 2 44 kDa subunit;
DE            Short=BTF2 p44;
DE   AltName: Full=General transcription factor IIH polypeptide 2;
DE   AltName: Full=TFIIH basal transcription factor complex p44 subunit;
GN   Name=GTF2H2; Synonyms=BTF2P44;
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0002031; P:G-protein coupled receptor internalization; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0009411; P:response to UV; TAS:ProtInc.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:GOC.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TF2H5_HUMAN             Reviewed;          71 AA.
AC   Q6ZYL4; Q0P5V8;
DE   RecName: Full=General transcription factor IIH subunit 5;
DE   AltName: Full=General transcription factor IIH polypeptide 5;
DE   AltName: Full=TFB5 ortholog;
DE   AltName: Full=TFIIH basal transcription factor complex TTD-A subunit;
GN   Name=GTF2H5; Synonyms=C6orf175, TTDA;
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TF2LX_HUMAN             Reviewed;         241 AA.
AC   Q8IUE1; Q5JRM9; Q8TD48;
DE   RecName: Full=Homeobox protein TGIF2LX;
DE   AltName: Full=TGF-beta-induced transcription factor 2-like protein;
DE   AltName: Full=TGFB-induced factor 2-like protein, X-linked;
DE   AltName: Full=TGIF-like on the X;
GN   Name=TGIF2LX; Synonyms=TGIFLX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TF2L1_HUMAN             Reviewed;         479 AA.
AC   Q9NZI6; Q4ZG43;
DE   RecName: Full=Transcription factor CP2-like protein 1;
DE   AltName: Full=CP2-related transcriptional repressor 1;
DE            Short=CRTR-1;
DE   AltName: Full=Transcription factor LBP-9;
GN   Name=TFCP2L1; Synonyms=CRTR1, LBP9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0007028; P:cytoplasm organization; IEA:Ensembl.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR   GO; GO:0002070; P:epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045927; P:positive regulation of growth; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007431; P:salivary gland development; IEA:Ensembl.
DR   GO; GO:0006694; P:steroid biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TF2H3_HUMAN             Reviewed;         308 AA.
AC   Q13889; B2R819; Q7L0G0; Q96AT7;
DE   RecName: Full=General transcription factor IIH subunit 3;
DE   AltName: Full=Basic transcription factor 2 34 kDa subunit;
DE            Short=BTF2 p34;
DE   AltName: Full=General transcription factor IIH polypeptide 3;
DE   AltName: Full=TFIIH basal transcription factor complex p34 subunit;
GN   Name=GTF2H3;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0008135; F:translation factor activity, nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:GOC.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TF2LY_HUMAN             Reviewed;         185 AA.
AC   Q8IUE0; A2VCU1;
DE   RecName: Full=Homeobox protein TGIF2LY;
DE   AltName: Full=TGF-beta-induced transcription factor 2-like protein;
DE   AltName: Full=TGFB-induced factor 2-like protein, Y-linked;
DE   AltName: Full=TGIF-like on the Y;
GN   Name=TGIF2LY; Synonyms=TGIFLY;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TF2H4_HUMAN             Reviewed;         462 AA.
AC   Q92759; Q76KU4;
DE   RecName: Full=General transcription factor IIH subunit 4;
DE   AltName: Full=Basic transcription factor 2 52 kDa subunit;
DE            Short=BTF2 p52;
DE   AltName: Full=General transcription factor IIH polypeptide 4;
DE   AltName: Full=TFIIH basal transcription factor complex p52 subunit;
GN   Name=GTF2H4;
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006370; P:7-methylguanosine mRNA capping; TAS:Reactome.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:GOC.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TF3A_HUMAN              Reviewed;         365 AA.
AC   Q92664; B7ZBK5; Q12963; Q13097;
DE   RecName: Full=Transcription factor IIIA;
DE            Short=TFIIIA;
GN   Name=GTF3A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009303; P:rRNA transcription; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   TF3B_HUMAN              Reviewed;         677 AA.
AC   Q92994; B3KU36; B4DIG5; B7Z2N3; F5H5Z7; F8WA46; Q13223; Q3SYD9;
AC   Q5PR24; Q6IQ02; Q96KX3; Q9HCW6; Q9HCW7; Q9HCW8;
DE   RecName: Full=Transcription factor IIIB 90 kDa subunit;
DE            Short=TFIIIB90;
DE            Short=hTFIIIB90;
DE   AltName: Full=B-related factor 1;
DE            Short=BRF-1;
DE            Short=hBRF;
DE   AltName: Full=TAF3B2;
DE   AltName: Full=TATA box-binding protein-associated factor, RNA polymerase III, subunit 2;
GN   Name=BRF1; Synonyms=BRF, GTF3B, TAF3B2, TAF3C;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:Ensembl.
DR   GO; GO:0009303; P:rRNA transcription; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
DR   GO; GO:0006384; P:transcription initiation from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0009304; P:tRNA transcription; TAS:ProtInc.
//
ID   TF3C1_HUMAN             Reviewed;        2109 AA.
AC   Q12789; B2RP21; Q12838; Q6DKN9; Q9Y4W9;
DE   RecName: Full=General transcription factor 3C polypeptide 1;
DE   AltName: Full=TF3C-alpha;
DE   AltName: Full=TFIIIC box B-binding subunit;
DE   AltName: Full=Transcription factor IIIC 220 kDa subunit;
DE            Short=TFIIIC 220 kDa subunit;
DE            Short=TFIIIC220;
DE   AltName: Full=Transcription factor IIIC subunit alpha;
GN   Name=GTF3C1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042791; P:5S class rRNA transcription from RNA polymerase III type 1 promoter; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0009303; P:rRNA transcription; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IC:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IC:HGNC.
DR   GO; GO:0009304; P:tRNA transcription; TAS:ProtInc.
DR   GO; GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IC:HGNC.
//
ID   TF3C2_HUMAN             Reviewed;         911 AA.
AC   Q8WUA4; D6W557; Q16632; Q9BWI7;
DE   RecName: Full=General transcription factor 3C polypeptide 2;
DE   AltName: Full=TF3C-beta;
DE   AltName: Full=Transcription factor IIIC 110 kDa subunit;
DE            Short=TFIIIC 110 kDa subunit;
DE            Short=TFIIIC110;
DE   AltName: Full=Transcription factor IIIC subunit beta;
GN   Name=GTF3C2; Synonyms=KIAA0011;
DR   GO; GO:0042791; P:5S class rRNA transcription from RNA polymerase III type 1 promoter; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IDA:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IC:HGNC.
//
ID   TF3C3_HUMAN             Reviewed;         886 AA.
AC   Q9Y5Q9; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97;
DE   RecName: Full=General transcription factor 3C polypeptide 3;
DE   AltName: Full=Transcription factor IIIC 102 kDa subunit;
DE            Short=TFIIIC 102 kDa subunit;
DE            Short=TFIIIC102;
DE   AltName: Full=Transcription factor IIIC subunit gamma;
DE            Short=TF3C-gamma;
GN   Name=GTF3C3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042791; P:5S class rRNA transcription from RNA polymerase III type 1 promoter; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IC:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IC:HGNC.
DR   GO; GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IC:HGNC.
//
ID   TF3C4_HUMAN             Reviewed;         822 AA.
AC   Q9UKN8; Q5VZJ7;
DE   RecName: Full=General transcription factor 3C polypeptide 4;
DE            EC=2.3.1.48;
DE   AltName: Full=TF3C-delta;
DE   AltName: Full=Transcription factor IIIC 90 kDa subunit;
DE            Short=TFIIIC 90 kDa subunit;
DE            Short=TFIIIC90;
DE   AltName: Full=Transcription factor IIIC subunit delta;
GN   Name=GTF3C4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0004402; F:histone acetyltransferase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042791; P:5S class rRNA transcription from RNA polymerase III type 1 promoter; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; TAS:GOC.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IC:HGNC.
DR   GO; GO:0006384; P:transcription initiation from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IC:HGNC.
DR   GO; GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IC:HGNC.
//
ID   TF3C5_HUMAN             Reviewed;         519 AA.
AC   Q9Y5Q8; A6NI44; A6NJB9; Q5T7U2; Q5T7U3; Q8N2U7; Q8N857; Q96GD9;
AC   Q9H4P2;
DE   RecName: Full=General transcription factor 3C polypeptide 5;
DE   AltName: Full=TF3C-epsilon;
DE   AltName: Full=Transcription factor IIIC 63 kDa subunit;
DE            Short=TFIIIC 63 kDa subunit;
DE            Short=TFIIIC63;
DE   AltName: Full=Transcription factor IIIC subunit epsilon;
GN   Name=GTF3C5; ORFNames=CDABP0017;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042791; P:5S class rRNA transcription from RNA polymerase III type 1 promoter; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IC:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IC:HGNC.
DR   GO; GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IC:HGNC.
//
ID   TF3C6_HUMAN             Reviewed;         213 AA.
AC   Q969F1; Q5VXN2;
DE   RecName: Full=General transcription factor 3C polypeptide 6;
DE   AltName: Full=Transcription factor IIIC 35 kDa subunit;
DE            Short=TFIIIC 35 kDa subunit;
DE            Short=TFIIIC35;
DE   AltName: Full=Transcription factor IIIC subunit 6;
GN   Name=GTF3C6; Synonyms=C6orf51; ORFNames=CDA020, NPD020;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0042791; P:5S class rRNA transcription from RNA polymerase III type 1 promoter; IC:HGNC.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; IDA:HGNC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IC:HGNC.
//
ID   TF65_HUMAN              Reviewed;         551 AA.
AC   Q04206; Q6GTV1; Q6SLK1;
DE   RecName: Full=Transcription factor p65;
DE   AltName: Full=Nuclear factor NF-kappa-B p65 subunit;
DE   AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;
GN   Name=RELA; Synonyms=NFKB3;
DR   GO; GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.
DR   GO; GO:0042301; F:phosphate ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006117; P:acetaldehyde metabolic process; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; NAS:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0071347; P:cellular response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; NAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0046627; P:negative regulation of insulin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070431; P:nucleotide-binding oligomerization domain containing 2 signaling pathway; IDA:MGI.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.
DR   GO; GO:0014040; P:positive regulation of Schwann cell differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0033590; P:response to cobalamin; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IGI:BHF-UCL.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IDA:UniProtKB.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0010224; P:response to UV-B; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TF7L1_HUMAN             Reviewed;         588 AA.
AC   Q9HCS4; Q53R97; Q6PD70; Q9NP00;
DE   RecName: Full=Transcription factor 7-like 1;
DE   AltName: Full=HMG box transcription factor 3;
DE            Short=TCF-3;
GN   Name=TCF7L1; Synonyms=TCF3;
DR   GO; GO:0008013; F:beta-catenin binding; IBA:RefGenome.
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IBA:RefGenome.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; IEA:Ensembl.
DR   GO; GO:0048319; P:axial mesoderm morphogenesis; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0006325; P:chromatin organization; NAS:UniProtKB.
DR   GO; GO:0048699; P:generation of neurons; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0046022; P:positive regulation of transcription from RNA polymerase II promoter during mitosis; IEA:Ensembl.
DR   GO; GO:2000036; P:regulation of stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TF7L2_HUMAN             Reviewed;         619 AA.
AC   Q9NQB0; B4DRJ8; B9X074; C6ZRJ8; C6ZRK0; E2GH14; E2GH19; E2GH20;
AC   E2GH24; E2GH25; E9PFH9; F8W742; F8W7T5; O00185; Q9NQB1; Q9NQB2;
AC   Q9NQB3; Q9NQB4; Q9NQB5; Q9NQB6; Q9NQB7; Q9ULC2;
DE   RecName: Full=Transcription factor 7-like 2;
DE   AltName: Full=HMG box transcription factor 4;
DE   AltName: Full=T-cell-specific transcription factor 4;
DE            Short=T-cell factor 4;
DE            Short=TCF-4;
DE            Short=hTCF-4;
GN   Name=TCF7L2; Synonyms=TCF4;
DR   GO; GO:0070016; F:armadillo repeat domain binding; IPI:BHF-UCL.
DR   GO; GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IBA:RefGenome.
DR   GO; GO:0045295; F:gamma-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0035257; F:nuclear hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IMP:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; IMP:BHF-UCL.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IC:BHF-UCL.
DR   GO; GO:0044334; P:canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0035411; P:catenin import into nucleus; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.
DR   GO; GO:0008283; P:cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0048557; P:embryonic digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0030538; P:embryonic genitalia morphogenesis; IEA:Ensembl.
DR   GO; GO:0048619; P:embryonic hindgut morphogenesis; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0045444; P:fat cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0048699; P:generation of neurons; IBA:RefGenome.
DR   GO; GO:0042593; P:glucose homeostasis; IDA:BHF-UCL.
DR   GO; GO:0043570; P:maintenance of DNA repeat elements; IMP:BHF-UCL.
DR   GO; GO:0048625; P:myoblast fate commitment; IDA:BHF-UCL.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0046621; P:negative regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:2000675; P:negative regulation of type B pancreatic cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0021915; P:neural tube development; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0031016; P:pancreas development; TAS:BHF-UCL.
DR   GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010909; P:positive regulation of heparan sulfate proteoglycan biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IMP:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0032350; P:regulation of hormone metabolic process; IDA:BHF-UCL.
DR   GO; GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0048713; P:regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048641; P:regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0048660; P:regulation of smooth muscle cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; ISS:BHF-UCL.
DR   GO; GO:0032252; P:secretory granule localization; IEA:Ensembl.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFAM_HUMAN              Reviewed;         246 AA.
AC   Q00059; A8MRB2; A9QXC6; B5BU05; Q5U0C6;
DE   RecName: Full=Transcription factor A, mitochondrial;
DE            Short=mtTFA;
DE   AltName: Full=Mitochondrial transcription factor 1;
DE            Short=MtTF1;
DE   AltName: Full=Transcription factor 6;
DE            Short=TCF-6;
DE   AltName: Full=Transcription factor 6-like 2;
DE   Flags: Precursor;
GN   Name=TFAM; Synonyms=TCF6, TCF6L2;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0070363; F:mitochondrial light strand promoter sense binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0033108; P:mitochondrial respiratory chain complex assembly; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006356; P:regulation of transcription from RNA polymerase I promoter; TAS:ProtInc.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IMP:UniProtKB.
DR   GO; GO:0006391; P:transcription initiation from mitochondrial promoter; IDA:UniProtKB.
//
ID   TFAP4_HUMAN             Reviewed;         338 AA.
AC   Q01664; O60409;
DE   RecName: Full=Transcription factor AP-4;
DE   AltName: Full=Activating enhancer-binding protein 4;
DE   AltName: Full=Class C basic helix-loop-helix protein 41;
DE            Short=bHLHc41;
GN   Name=TFAP4; Synonyms=BHLHC41;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IDA:UniProtKB.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001269; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   TFB1M_HUMAN             Reviewed;         346 AA.
AC   Q8WVM0; Q05DR0; Q9Y384;
DE   RecName: Full=Dimethyladenosine transferase 1, mitochondrial;
DE            EC=2.1.1.-;
DE   AltName: Full=Mitochondrial 12S rRNA dimethylase 1;
DE   AltName: Full=Mitochondrial transcription factor B1;
DE            Short=h-mtTFB;
DE            Short=h-mtTFB1;
DE            Short=hTFB1M;
DE            Short=mtTFB1;
DE   AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1;
DE   Flags: Precursor;
GN   Name=TFB1M; ORFNames=CGI-75;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFB2M_HUMAN             Reviewed;         396 AA.
AC   Q9H5Q4; Q9H626;
DE   RecName: Full=Dimethyladenosine transferase 2, mitochondrial;
DE            EC=2.1.1.-;
DE   AltName: Full=Hepatitis C virus NS5A-transactivated protein 5;
DE            Short=HCV NS5A-transactivated protein 5;
DE   AltName: Full=Mitochondrial 12S rRNA dimethylase 2;
DE   AltName: Full=Mitochondrial transcription factor B2;
DE            Short=h-mtTFB;
DE            Short=h-mtTFB2;
DE            Short=hTFB2M;
DE            Short=mtTFB2;
DE   AltName: Full=S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2;
DE   Flags: Precursor;
GN   Name=TFB2M; Synonyms=NS5ATP5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006390; P:transcription from mitochondrial promoter; IDA:UniProtKB.
DR   GO; GO:0006391; P:transcription initiation from mitochondrial promoter; IDA:UniProtKB.
//
ID   TFCP2_HUMAN             Reviewed;         502 AA.
AC   Q12800; A8K5E9; Q12801; Q9UD75; Q9UD77;
DE   RecName: Full=Alpha-globin transcription factor CP2;
DE   AltName: Full=SAA3 enhancer factor;
DE   AltName: Full=Transcription factor LSF;
GN   Name=TFCP2; Synonyms=LSF, SEF;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFDP2_HUMAN             Reviewed;         446 AA.
AC   Q14188; B7Z8C8; B7Z8L5; D3DNG1; E9PFC3; F8WAI2; Q13331; Q14187;
AC   Q6R754; Q8WU88; Q9UG28;
DE   RecName: Full=Transcription factor Dp-2;
DE   AltName: Full=E2F dimerization partner 2;
GN   Name=TFDP2; Synonyms=DP2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   TFDP1_HUMAN             Reviewed;         410 AA.
AC   Q14186; Q5JSB4; Q8IZL5;
DE   RecName: Full=Transcription factor Dp-1;
DE   AltName: Full=DRTF1-polypeptide 1;
DE            Short=DRTF1;
DE   AltName: Full=E2F dimerization partner 1;
GN   Name=TFDP1; Synonyms=DP1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   TFE2_HUMAN              Reviewed;         654 AA.
AC   P15923; P15883; Q14208; Q14635; Q14636; Q2TB40; Q9UPI9;
DE   RecName: Full=Transcription factor E2-alpha;
DE   AltName: Full=Class B basic helix-loop-helix protein 21;
DE            Short=bHLHb21;
DE   AltName: Full=Immunoglobulin enhancer-binding factor E12/E47;
DE   AltName: Full=Immunoglobulin transcription factor 1;
DE   AltName: Full=Kappa-E2-binding factor;
DE   AltName: Full=Transcription factor 3;
DE            Short=TCF-3;
DE   AltName: Full=Transcription factor ITF-1;
GN   Name=TCF3; Synonyms=BHLHB21, E2A, ITF1;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0070888; F:E-box binding; IDA:UniProtKB.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0070491; F:repressing transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0070644; F:vitamin D response element binding; IDA:BHF-UCL.
DR   GO; GO:0030183; P:B cell differentiation; NAS:UniProtKB.
DR   GO; GO:0002326; P:B cell lineage commitment; IDA:UniProtKB.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0043966; P:histone H3 acetylation; IEA:Ensembl.
DR   GO; GO:0043967; P:histone H4 acetylation; IEA:Ensembl.
DR   GO; GO:0033152; P:immunoglobulin V(D)J recombination; IDA:MGI.
DR   GO; GO:0042692; P:muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0048541; P:Peyer's patch development; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   TFDP3_HUMAN             Reviewed;         405 AA.
AC   Q5H9I0; Q6DK49; Q9NZ54;
DE   RecName: Full=Transcription factor Dp family member 3;
DE   AltName: Full=Cancer/testis antigen 30;
DE            Short=CT30;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 661;
GN   Name=TFDP3; Synonyms=DP4, HCA661;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFE3_HUMAN              Reviewed;         575 AA.
AC   P19532; A8MZL6; Q92757; Q92758; Q99964;
DE   RecName: Full=Transcription factor E3;
DE   AltName: Full=Class E basic helix-loop-helix protein 33;
DE            Short=bHLHe33;
GN   Name=TFE3; Synonyms=BHLHE33;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; ISS:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045670; P:regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFEB_HUMAN              Reviewed;         476 AA.
AC   P19484; Q709B3; Q7Z6P9; Q9BRJ5; Q9UJD8;
DE   RecName: Full=Transcription factor EB;
DE   AltName: Full=Class E basic helix-loop-helix protein 35;
DE            Short=bHLHe35;
GN   Name=TFEB; Synonyms=BHLHE35;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0001892; P:embryonic placenta development; ISS:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; ISS:UniProtKB.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFEC_HUMAN              Reviewed;         347 AA.
AC   O14948; B2R8X5; Q5H9U8; Q709A4; Q8N6J9;
DE   RecName: Full=Transcription factor EC;
DE            Short=TFE-C;
DE   AltName: Full=Class E basic helix-loop-helix protein 34;
DE            Short=bHLHe34;
DE   AltName: Full=Transcription factor EC-like;
DE            Short=hTFEC-L;
GN   Name=TFEC; Synonyms=BHLHE34, TCFEC, TFECL;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFF1_HUMAN              Reviewed;          84 AA.
AC   P04155;
DE   RecName: Full=Trefoil factor 1;
DE   AltName: Full=Breast cancer estrogen-inducible protein;
DE   AltName: Full=PNR-2;
DE   AltName: Full=Polypeptide P1.A;
DE            Short=hP1.A;
DE   AltName: Full=Protein pS2;
DE   Flags: Precursor;
GN   Name=TFF1; Synonyms=BCEI, PS2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; NAS:ProtInc.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0010039; P:response to iron ion; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
//
ID   TFF2_HUMAN              Reviewed;         129 AA.
AC   Q03403; Q15854;
DE   RecName: Full=Trefoil factor 2;
DE   AltName: Full=Spasmolysin;
DE   AltName: Full=Spasmolytic polypeptide;
DE            Short=SP;
DE   Flags: Precursor;
GN   Name=TFF2; Synonyms=SML1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0060455; P:negative regulation of gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043031; P:negative regulation of macrophage activation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
//
ID   TFF3_HUMAN              Reviewed;          80 AA.
AC   Q07654; E9PBB5; Q96NX0; Q9UDA5;
DE   RecName: Full=Trefoil factor 3;
DE   AltName: Full=Intestinal trefoil factor;
DE            Short=hITF;
DE   AltName: Full=Polypeptide P1.B;
DE            Short=hP1.B;
DE   Flags: Precursor;
GN   Name=TFF3; Synonyms=ITF, TFI;
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
//
ID   TFG_HUMAN               Reviewed;         400 AA.
AC   Q92734; D3DN49; G5E9V1; Q15656; Q969I2;
DE   RecName: Full=Protein TFG;
DE   AltName: Full=TRK-fused gene protein;
GN   Name=TFG;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TFIP8_HUMAN             Reviewed;         198 AA.
AC   O95379; B3KMH1; B3KMI2; B7Z713; Q9P1Q1; Q9UER5; Q9UP47;
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 8;
DE            Short=TNF alpha-induced protein 8;
DE   AltName: Full=Head and neck tumor and metastasis-related protein;
DE   AltName: Full=MDC-3.13;
DE   AltName: Full=NF-kappa-B-inducible DED-containing protein;
DE            Short=NDED;
DE   AltName: Full=SCC-S2;
DE   AltName: Full=TNF-induced protein GG2-1;
GN   Name=TNFAIP8;
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:GOC.
//
ID   TFP11_HUMAN             Reviewed;         837 AA.
AC   Q9UBB9; O95908; Q20WL0; Q5H8V8; Q9UGV7; Q9Y2Q8;
DE   RecName: Full=Tuftelin-interacting protein 11;
DE   AltName: Full=Septin and tuftelin-interacting protein 1;
DE            Short=STIP-1;
GN   Name=TFIP11; Synonyms=STIP; ORFNames=HSPC006;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IC:UniProtKB.
DR   GO; GO:0000390; P:spliceosomal complex disassembly; IMP:UniProtKB.
//
ID   TFPI1_HUMAN             Reviewed;         304 AA.
AC   P10646; O95103; Q53TS4;
DE   RecName: Full=Tissue factor pathway inhibitor;
DE            Short=TFPI;
DE   AltName: Full=Extrinsic pathway inhibitor;
DE            Short=EPI;
DE   AltName: Full=Lipoprotein-associated coagulation inhibitor;
DE            Short=LACI;
DE   Flags: Precursor;
GN   Name=TFPI; Synonyms=LACI, TFPI1;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007598; P:blood coagulation, extrinsic pathway; TAS:Reactome.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
//
ID   TFPI2_HUMAN             Reviewed;         235 AA.
AC   P48307; Q66ME8; Q9UC86;
DE   RecName: Full=Tissue factor pathway inhibitor 2;
DE            Short=TFPI-2;
DE   AltName: Full=Placental protein 5;
DE            Short=PP5;
DE   Flags: Precursor;
GN   Name=TFPI2;
DR   GO; GO:0005201; F:extracellular matrix structural constituent; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
//
ID   TFPT_HUMAN              Reviewed;         253 AA.
AC   P0C1Z6;
DE   RecName: Full=TCF3 fusion partner;
DE   AltName: Full=INO80 complex subunit F;
DE   AltName: Full=Protein FB1;
GN   Name=TFPT; Synonyms=INO80F;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TFR1_HUMAN              Reviewed;         760 AA.
AC   P02786; D3DXB0; Q1HE24; Q59G55; Q9UCN0; Q9UCU5; Q9UDF9; Q9UK21;
DE   RecName: Full=Transferrin receptor protein 1;
DE            Short=TR;
DE            Short=TfR;
DE            Short=TfR1;
DE            Short=Trfr;
DE   AltName: Full=T9;
DE   AltName: Full=p90;
DE   AltName: CD_antigen=CD71;
DE   Contains:
DE     RecName: Full=Transferrin receptor protein 1, serum form;
DE              Short=sTfR;
GN   Name=TFRC;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004998; F:transferrin receptor activity; NAS:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; NAS:UniProtKB.
DR   GO; GO:0097286; P:iron ion import; IDA:UniProt.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:GOC.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TFR2_HUMAN              Reviewed;         801 AA.
AC   Q9UP52; A6NGM7; O75422; Q1HE13; Q9HA99; Q9NX67;
DE   RecName: Full=Transferrin receptor protein 2;
DE            Short=TfR2;
GN   Name=TFR2;
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0004998; F:transferrin receptor activity; NAS:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0006826; P:iron ion transport; NAS:UniProtKB.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; NAS:GOC.
//
ID   TF_HUMAN                Reviewed;         295 AA.
AC   P13726; D3DT47; Q6FHG2; Q86WH4;
DE   RecName: Full=Tissue factor;
DE            Short=TF;
DE   AltName: Full=Coagulation factor III;
DE   AltName: Full=Thromboplastin;
DE   AltName: CD_antigen=CD142;
DE   Flags: Precursor;
GN   Name=F3;
DR   GO; GO:0005543; F:phospholipid binding; IDA:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0002543; P:activation of blood coagulation via clotting cascade; IC:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0002541; P:activation of plasma proteins involved in acute inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007598; P:blood coagulation, extrinsic pathway; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; TAS:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010641; P:positive regulation of platelet-derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IC:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:BHF-UCL.
//
ID   TGBR3_HUMAN             Reviewed;         851 AA.
AC   Q03167; A0AUW8; A8K5N0; B9EG88; Q5T2T4; Q5U731; Q9UGI2;
DE   RecName: Full=Transforming growth factor beta receptor type 3;
DE            Short=TGF-beta receptor type 3;
DE            Short=TGFR-3;
DE   AltName: Full=Betaglycan;
DE   AltName: Full=Transforming growth factor beta receptor III;
DE            Short=TGF-beta receptor type III;
DE   Flags: Precursor;
GN   Name=TGFBR3;
DR   GO; GO:0015026; F:coreceptor activity; IDA:BHF-UCL.
DR   GO; GO:0005539; F:glycosaminoglycan binding; ISS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; ISS:BHF-UCL.
DR   GO; GO:0030165; F:PDZ domain binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046332; F:SMAD binding; IMP:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IDA:BHF-UCL.
DR   GO; GO:0070123; F:transforming growth factor beta receptor activity, type III; IDA:BHF-UCL.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; ISS:BHF-UCL.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0001568; P:blood vessel development; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0016049; P:cell growth; ISS:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; ISS:BHF-UCL.
DR   GO; GO:0060318; P:definitive erythrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0060216; P:definitive hemopoiesis; ISS:BHF-UCL.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060347; P:heart trabecula formation; ISS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IMP:BHF-UCL.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:BHF-UCL.
DR   GO; GO:0001889; P:liver development; ISS:BHF-UCL.
DR   GO; GO:0051271; P:negative regulation of cellular component movement; IDA:BHF-UCL.
DR   GO; GO:0010633; P:negative regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0032354; P:response to follicle-stimulating hormone; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0034699; P:response to luteinizing hormone; IDA:BHF-UCL.
DR   GO; GO:0034695; P:response to prostaglandin E; IDA:BHF-UCL.
DR   GO; GO:0007181; P:transforming growth factor beta receptor complex assembly; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:BHF-UCL.
//
ID   TGDS_HUMAN              Reviewed;         350 AA.
AC   O95455; Q5T3Z2; Q9H1T9;
DE   RecName: Full=dTDP-D-glucose 4,6-dehydratase;
DE            EC=4.2.1.46;
GN   Name=TGDS;
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009225; P:nucleotide-sugar metabolic process; IEA:InterPro.
//
ID   TGFA1_HUMAN             Reviewed;         860 AA.
AC   Q8WUH2; A8K5R7; D3DVJ8; O60466;
DE   RecName: Full=Transforming growth factor-beta receptor-associated protein 1;
DE            Short=TGF-beta receptor-associated protein 1;
DE            Short=TRAP-1;
DE            Short=TRAP1;
GN   Name=TGFBRAP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046332; F:SMAD binding; IDA:UniProtKB.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   TGFA_HUMAN              Reviewed;         160 AA.
AC   P01135; A8K286; Q15577; Q53SK7; Q9BS56; Q9UEI3; Q9UKM1; Q9UKM2;
AC   Q9UKM3;
DE   RecName: Full=Protransforming growth factor alpha;
DE   Contains:
DE     RecName: Full=Transforming growth factor alpha;
DE              Short=TGF-alpha;
DE     AltName: Full=EGF-like TGF;
DE              Short=ETGF;
DE     AltName: Full=TGF type 1;
DE   Flags: Precursor;
GN   Name=TGFA;
DR   GO; GO:0005154; F:epidermal growth factor receptor binding; IDA:UniProtKB.
DR   GO; GO:0008083; F:growth factor activity; IDA:HGNC.
DR   GO; GO:0004708; F:MAP kinase kinase activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:HGNC.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IDA:GOC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:HGNC.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IDA:HGNC.
DR   GO; GO:0045840; P:positive regulation of mitosis; IDA:HGNC.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   TGFB1_HUMAN             Reviewed;         390 AA.
AC   P01137; A8K792; Q9UCG4;
DE   RecName: Full=Transforming growth factor beta-1;
DE            Short=TGF-beta-1;
DE   Contains:
DE     RecName: Full=Latency-associated peptide;
DE              Short=LAP;
DE   Flags: Precursor;
GN   Name=TGFB1; Synonyms=TGFB;
DR   GO; GO:0003823; F:antigen binding; IPI:UniProt.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0046732; P:active induction of host immune response by virus; TAS:Reactome.
DR   GO; GO:0002460; P:adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006754; P:ATP biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060751; P:branch elongation involved in mammary gland duct branching; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0045216; P:cell-cell junction organization; IDA:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071549; P:cellular response to dexamethasone stimulus; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0002248; P:connective tissue replacement involved in inflammatory response wound healing; TAS:BHF-UCL.
DR   GO; GO:0009817; P:defense response to fungus, incompatible interaction; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0019049; P:evasion or tolerance of host defenses by virus; IDA:BHF-UCL.
DR   GO; GO:0085029; P:extracellular matrix assembly; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0060364; P:frontal suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0008354; P:germ cell migration; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IDA:UniProtKB.
DR   GO; GO:0030214; P:hyaluronan catabolic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0048535; P:lymph node development; ISS:UniProtKB.
DR   GO; GO:0010742; P:macrophage derived foam cell differentiation; IC:BHF-UCL.
DR   GO; GO:0060744; P:mammary gland branching involved in thelarche; IEA:Ensembl.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:BHF-UCL.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; TAS:Reactome.
DR   GO; GO:0032943; P:mononuclear cell proliferation; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IDA:HGNC.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:BHF-UCL.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IDA:UniProtKB.
DR   GO; GO:1900126; P:negative regulation of hyaluronan biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0050777; P:negative regulation of immune response; IEA:Ensembl.
DR   GO; GO:0010936; P:negative regulation of macrophage cytokine production; IDA:DFLAT.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:BHF-UCL.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
DR   GO; GO:0050765; P:negative regulation of phagocytosis; IEA:Ensembl.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051280; P:negative regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0043932; P:ossification involved in bone remodeling; IEP:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006796; P:phosphate-containing compound metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEP:BHF-UCL.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0031536; P:positive regulation of exit from mitosis; IEA:Ensembl.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0035066; P:positive regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0031065; P:positive regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:0032740; P:positive regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0048298; P:positive regulation of isotype switching to IgA isotypes; IDA:MGI.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:1901666; P:positive regulation of NAD+ ADP-ribosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0042482; P:positive regulation of odontogenesis; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IDA:BHF-UCL.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0035307; P:positive regulation of protein dephosphorylation; IDA:BHF-UCL.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051152; P:positive regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0032930; P:positive regulation of superoxide anion generation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; TAS:BHF-UCL.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0032801; P:receptor catabolic process; IDA:BHF-UCL.
DR   GO; GO:0051098; P:regulation of binding; ISS:UniProtKB.
DR   GO; GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0061035; P:regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; TAS:BHF-UCL.
DR   GO; GO:0051101; P:regulation of DNA binding; ISS:UniProtKB.
DR   GO; GO:0042306; P:regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045066; P:regulatory T cell differentiation; IEA:Ensembl.
DR   GO; GO:0070723; P:response to cholesterol; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IDA:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IDA:BHF-UCL.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IEP:BHF-UCL.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEP:BHF-UCL.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0002513; P:tolerance induction to self antigen; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
//
ID   TGFB2_HUMAN             Reviewed;         414 AA.
AC   P61812; B4DKC5; P08112; Q15579; Q15581; Q4VAV9;
DE   RecName: Full=Transforming growth factor beta-2;
DE            Short=TGF-beta-2;
DE   AltName: Full=BSC-1 cell growth inhibitor;
DE   AltName: Full=Cetermin;
DE   AltName: Full=Glioblastoma-derived T-cell suppressor factor;
DE            Short=G-TSF;
DE   AltName: Full=Polyergin;
DE   Contains:
DE     RecName: Full=Latency-associated peptide;
DE              Short=LAP;
DE   Flags: Precursor;
GN   Name=TGFB2;
DR   GO; GO:0001540; F:beta-amyloid binding; IDA:UniProtKB.
DR   GO; GO:0005125; F:cytokine activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; TAS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IMP:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; IDA:UniProtKB.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; TAS:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0060038; P:cardiac muscle cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010002; P:cardioblast differentiation; IDA:UniProtKB.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0042637; P:catagen; IDA:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0008219; P:cell death; IDA:UniProtKB.
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; IDA:BHF-UCL.
DR   GO; GO:0000902; P:cell morphogenesis; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0045216; P:cell-cell junction organization; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0030199; P:collagen fibril organization; IDA:BHF-UCL.
DR   GO; GO:0042416; P:dopamine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0009790; P:embryo development; TAS:UniProtKB.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEP:DFLAT.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001654; P:eye development; IDA:UniProtKB.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0048699; P:generation of neurons; TAS:UniProtKB.
DR   GO; GO:0008347; P:glial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001942; P:hair follicle development; IDA:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IDA:UniProtKB.
DR   GO; GO:0003007; P:heart morphogenesis; IDA:BHF-UCL.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0022601; P:menstrual cycle phase; IEP:BHF-UCL.
DR   GO; GO:0010693; P:negative regulation of alkaline phosphatase activity; IDA:BHF-UCL.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.
DR   GO; GO:0010936; P:negative regulation of macrophage cytokine production; IDA:DFLAT.
DR   GO; GO:0048666; P:neuron development; ISS:UniProtKB.
DR   GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; ISS:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; NAS:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0070237; P:positive regulation of activation-induced cell death of T cells; IEA:Ensembl.
DR   GO; GO:0051891; P:positive regulation of cardioblast differentiation; IDA:UniProtKB.
DR   GO; GO:0051795; P:positive regulation of catagen; IDA:UniProtKB.
DR   GO; GO:0033630; P:positive regulation of cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045823; P:positive regulation of heart contraction; IDA:UniProtKB.
DR   GO; GO:0050778; P:positive regulation of immune response; ISS:UniProtKB.
DR   GO; GO:0045726; P:positive regulation of integrin biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045778; P:positive regulation of ossification; IEP:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032909; P:regulation of transforming growth factor beta2 production; IMP:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0032570; P:response to progesterone; IDA:BHF-UCL.
DR   GO; GO:0009611; P:response to wounding; IEP:BHF-UCL.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEP:BHF-UCL.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; IDA:GOC.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0048103; P:somatic stem cell division; ISS:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
//
ID   TGFB3_HUMAN             Reviewed;         412 AA.
AC   P10600;
DE   RecName: Full=Transforming growth factor beta-3;
DE            Short=TGF-beta-3;
DE   Contains:
DE     RecName: Full=Latency-associated peptide;
DE              Short=LAP;
DE   Flags: Precursor;
GN   Name=TGFB3;
DR   GO; GO:0042802; F:identical protein binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IDA:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016049; P:cell growth; IEA:InterPro.
DR   GO; GO:0045216; P:cell-cell junction organization; IDA:BHF-UCL.
DR   GO; GO:0070483; P:detection of hypoxia; IDA:BHF-UCL.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0048702; P:embryonic neurocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0060325; P:face morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0060364; P:frontal suture morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; ISS:BHF-UCL.
DR   GO; GO:0030879; P:mammary gland development; ISS:BHF-UCL.
DR   GO; GO:0022601; P:menstrual cycle phase; IEP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:BHF-UCL.
DR   GO; GO:0010936; P:negative regulation of macrophage cytokine production; IDA:DFLAT.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; NAS:BHF-UCL.
DR   GO; GO:0043932; P:ossification involved in bone remodeling; IEP:BHF-UCL.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEP:BHF-UCL.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:BHF-UCL.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; ISS:BHF-UCL.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IDA:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0034616; P:response to laminar fluid shear stress; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IDA:BHF-UCL.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEP:BHF-UCL.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
//
ID   TGFI1_HUMAN             Reviewed;         461 AA.
AC   O43294; B2R8D5; Q9BPW3; Q9Y2V5;
DE   RecName: Full=Transforming growth factor beta-1-induced transcript 1 protein;
DE   AltName: Full=Androgen receptor coactivator 55 kDa protein;
DE   AltName: Full=Androgen receptor-associated protein of 55 kDa;
DE   AltName: Full=Hydrogen peroxide-inducible clone 5 protein;
DE            Short=Hic-5;
GN   Name=TGFB1I1; Synonyms=ARA55;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:UniProtKB.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048495; F:Roundabout binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TGFR1_HUMAN             Reviewed;         503 AA.
AC   P36897; Q6IR47; Q706C0; Q706C1;
DE   RecName: Full=TGF-beta receptor type-1;
DE            Short=TGFR-1;
DE            EC=2.7.11.30;
DE   AltName: Full=Activin A receptor type II-like protein kinase of 53kD;
DE   AltName: Full=Activin receptor-like kinase 5;
DE            Short=ALK-5;
DE            Short=ALK5;
DE   AltName: Full=Serine/threonine-protein kinase receptor R4;
DE            Short=SKR4;
DE   AltName: Full=TGF-beta type I receptor;
DE   AltName: Full=Transforming growth factor-beta receptor type I;
DE            Short=TGF-beta receptor type I;
DE            Short=TbetaR-I;
DE   Flags: Precursor;
GN   Name=TGFBR1; Synonyms=ALK5, SKR4;
DR   GuidetoPHARMACOLOGY; 1788; -.
DR   GO; GO:0005524; F:ATP binding; IDA:HGNC.
DR   GO; GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0046332; F:SMAD binding; IDA:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IDA:BHF-UCL.
DR   GO; GO:0005025; F:transforming growth factor beta receptor activity, type I; IDA:BHF-UCL.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005114; F:type II transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001824; P:blastocyst development; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:UniProtKB.
DR   GO; GO:0048870; P:cell motility; IMP:BHF-UCL.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.
DR   GO; GO:0030199; P:collagen fibril organization; ISS:BHF-UCL.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0043542; P:endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0043062; P:extracellular structure organization; TAS:UniProtKB.
DR   GO; GO:0008354; P:germ cell migration; ISS:BHF-UCL.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; ISS:BHF-UCL.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0048762; P:mesenchymal cell differentiation; TAS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048663; P:neuron fate commitment; ISS:BHF-UCL.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0060017; P:parathyroid gland development; ISS:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0060037; P:pharyngeal system development; ISS:BHF-UCL.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IMP:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; IEA:Ensembl.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:BHF-UCL.
DR   GO; GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0043393; P:regulation of protein binding; IEA:Ensembl.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0070723; P:response to cholesterol; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IDA:HGNC.
DR   GO; GO:0001501; P:skeletal system development; ISS:BHF-UCL.
DR   GO; GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0048538; P:thymus development; ISS:BHF-UCL.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; TAS:UniProtKB.
//
ID   TGFR2_HUMAN             Reviewed;         567 AA.
AC   P37173; B4DTV5; Q15580; Q6DKT6; Q99474;
DE   RecName: Full=TGF-beta receptor type-2;
DE            Short=TGFR-2;
DE            EC=2.7.11.30;
DE   AltName: Full=TGF-beta type II receptor;
DE   AltName: Full=Transforming growth factor-beta receptor type II;
DE            Short=TGF-beta receptor type II;
DE            Short=TbetaR-II;
DE   Flags: Precursor;
GN   Name=TGFBR2;
DR   GuidetoPHARMACOLOGY; 1795; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IDA:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0046332; F:SMAD binding; IDA:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; IDA:BHF-UCL.
DR   GO; GO:0005026; F:transforming growth factor beta receptor activity, type II; IEA:InterPro.
DR   GO; GO:0005024; F:transforming growth factor beta-activated receptor activity; IDA:BHF-UCL.
DR   GO; GO:0004675; F:transmembrane receptor protein serine/threonine kinase activity; IDA:BHF-UCL.
DR   GO; GO:0034713; F:type I transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0034714; F:type III transforming growth factor beta receptor binding; IDA:BHF-UCL.
DR   GO; GO:0032147; P:activation of protein kinase activity; ISS:BHF-UCL.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0001568; P:blood vessel development; TAS:BHF-UCL.
DR   GO; GO:0007420; P:brain development; ISS:BHF-UCL.
DR   GO; GO:0060434; P:bronchus morphogenesis; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0035162; P:embryonic hemopoiesis; ISS:BHF-UCL.
DR   GO; GO:0007369; P:gastrulation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR   GO; GO:1990086; P:lens fiber cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0060463; P:lung lobe morphogenesis; IEA:Ensembl.
DR   GO; GO:0060443; P:mammary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; ISS:BHF-UCL.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0002663; P:positive regulation of B cell tolerance induction; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0051138; P:positive regulation of NK T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.
DR   GO; GO:0043415; P:positive regulation of skeletal muscle tissue regeneration; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0002666; P:positive regulation of T cell tolerance induction; ISS:BHF-UCL.
DR   GO; GO:0002651; P:positive regulation of tolerance induction to self antigen; ISS:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0070723; P:response to cholesterol; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IDA:BHF-UCL.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0060440; P:trachea formation; IEA:Ensembl.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; ISS:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   TGIF1_HUMAN             Reviewed;         401 AA.
AC   Q15583; A6NE42; A6NLU7; F8VZB6; Q6ICR0; Q8N5X9; Q9NRS0;
DE   RecName: Full=Homeobox protein TGIF1;
DE   AltName: Full=5'-TG-3'-interacting factor 1;
GN   Name=TGIF1; Synonyms=TGIF;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0007368; P:determination of left/right symmetry; IEA:Ensembl.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0038092; P:nodal signaling pathway; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0010470; P:regulation of gastrulation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   TGIF2_HUMAN             Reviewed;         237 AA.
AC   Q9GZN2; B2R9U3; E1P5T9; H0YNI0;
DE   RecName: Full=Homeobox protein TGIF2;
DE   AltName: Full=5'-TG-3'-interacting factor 2;
DE   AltName: Full=TGF-beta-induced transcription factor 2;
DE            Short=TGFB-induced factor 2;
GN   Name=TGIF2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   TGM1_HUMAN              Reviewed;         817 AA.
AC   P22735; Q197M4;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase K;
DE            EC=2.3.2.13;
DE   AltName: Full=Epidermal TGase;
DE   AltName: Full=Transglutaminase K;
DE            Short=TG(K);
DE            Short=TGK;
DE            Short=TGase K;
DE   AltName: Full=Transglutaminase-1;
DE            Short=TGase-1;
GN   Name=TGM1; Synonyms=KTG;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0043163; P:cell envelope organization; TAS:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
//
ID   TGM2_HUMAN              Reviewed;         687 AA.
AC   P21980; E1P5V9; Q16436; Q6B838; Q9BTN7; Q9UH35;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase 2;
DE            EC=2.3.2.13;
DE   AltName: Full=Tissue transglutaminase;
DE   AltName: Full=Transglutaminase C;
DE            Short=TG(C);
DE            Short=TGC;
DE            Short=TGase C;
DE   AltName: Full=Transglutaminase H;
DE            Short=TGase H;
DE   AltName: Full=Transglutaminase-2;
DE            Short=TGase-2;
GN   Name=TGM2;
DR   GO; GO:0005525; F:GTP binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0043277; P:apoptotic cell clearance; IDA:UniProtKB.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0018153; P:isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0060662; P:salivary gland cavitation; IEA:Ensembl.
//
ID   TGM3L_HUMAN             Reviewed;         706 AA.
AC   O95932; Q5JXU4; Q5JXU5; Q719M2; Q719M3; Q9Y4U8;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase 6;
DE            EC=2.3.2.13;
DE   AltName: Full=Transglutaminase Y;
DE            Short=TGY;
DE            Short=TGase Y;
DE   AltName: Full=Transglutaminase-3-like;
DE            Short=TGase-3-like;
DE   AltName: Full=Transglutaminase-6;
DE            Short=TG6;
DE            Short=TGase-6;
GN   Name=TGM6; Synonyms=TGM3L;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:MGI.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
//
ID   TGM3_HUMAN              Reviewed;         693 AA.
AC   Q08188; A8K5N6; B2RCR6; D3DVX1; O95933; Q32ML9; Q32MM0;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase E;
DE            EC=2.3.2.13;
DE   AltName: Full=Transglutaminase E;
DE            Short=TG(E);
DE            Short=TGE;
DE            Short=TGase E;
DE   AltName: Full=Transglutaminase-3;
DE            Short=TGase-3;
DE   Contains:
DE     RecName: Full=Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain;
DE   Contains:
DE     RecName: Full=Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain;
DE   Flags: Precursor;
GN   Name=TGM3;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0003824; F:catalytic activity; IDA:UniProtKB.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; TAS:UniProtKB.
DR   GO; GO:0043163; P:cell envelope organization; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; TAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:UniProtKB.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProtKB.
//
ID   TGM4_HUMAN              Reviewed;         684 AA.
AC   P49221; Q16707; Q96QN4;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase 4;
DE            EC=2.3.2.13;
DE   AltName: Full=Fibrinoligase;
DE   AltName: Full=Prostate transglutaminase;
DE   AltName: Full=Prostate-specific transglutaminase;
DE   AltName: Full=Transglutaminase P;
DE            Short=TG(P);
DE            Short=TGP;
DE            Short=TGase P;
DE   AltName: Full=Transglutaminase-4;
DE            Short=TGase-4;
GN   Name=TGM4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0042628; P:mating plug formation; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
//
ID   TGM5_HUMAN              Reviewed;         720 AA.
AC   O43548; O43549; Q0VF40; Q9UEZ4;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase 5;
DE            EC=2.3.2.13;
DE   AltName: Full=Transglutaminase X;
DE            Short=TG(X);
DE            Short=TGX;
DE            Short=TGase X;
DE   AltName: Full=Transglutaminase-5;
DE            Short=TGase-5;
GN   Name=TGM5; Synonyms=TGMX;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
//
ID   TGM7_HUMAN              Reviewed;         710 AA.
AC   Q96PF1;
DE   RecName: Full=Protein-glutamine gamma-glutamyltransferase Z;
DE   AltName: Full=Transglutaminase Z;
DE            Short=TG(Z);
DE            Short=TGZ;
DE            Short=TGase Z;
DE            EC=2.3.2.13;
DE   AltName: Full=Transglutaminase-7;
DE            Short=TGase-7;
GN   Name=TGM7;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0018149; P:peptide cross-linking; IEA:InterPro.
//
ID   TGON2_HUMAN             Reviewed;         480 AA.
AC   O43493; B2R686; B8ZZ88; D6W5K3; F8WBK2; O15282; O43492; O43499;
AC   O43500; O43501; Q53G68; Q53GV2; Q6MZV1; Q6ZTM7; Q8N6T8; Q92760;
AC   Q96QL2;
DE   RecName: Full=Trans-Golgi network integral membrane protein 2;
DE   AltName: Full=TGN38 homolog;
DE   AltName: Full=TGN46;
DE   AltName: Full=TGN48;
DE   AltName: Full=Trans-Golgi network protein TGN51;
DE   Flags: Precursor;
GN   Name=TGOLN2; Synonyms=TGN46, TGN51;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TGR3L_HUMAN             Reviewed;         316 AA.
AC   H3BV60;
DE   RecName: Full=Transforming growth factor-beta receptor type 3-like protein;
DE   AltName: Full=TGF-beta receptor type-3-like protein;
DE            Short=TGFR-3L;
DE   AltName: Full=Transforming growth factor-beta receptor type III-like protein;
DE            Short=TGF-beta receptor type III-like protein;
GN   Name=TGFBR3L;
//
ID   TGS1_HUMAN              Reviewed;         853 AA.
AC   Q96RS0; A6NJQ5; Q5GH23; Q8TDG9; Q96QU3; Q9H5V3;
DE   RecName: Full=Trimethylguanosine synthase;
DE            EC=2.1.1.-;
DE   AltName: Full=CLL-associated antigen KW-2;
DE   AltName: Full=Cap-specific guanine-N2 methyltransferase;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 137;
DE   AltName: Full=Nuclear receptor coactivator 6-interacting protein;
DE   AltName: Full=PRIP-interacting protein with methyltransferase motif;
DE            Short=PIMT;
DE            Short=PIPMT;
GN   Name=TGS1; Synonyms=HCA137, NCOA6IP, PIMT;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071164; F:RNA trimethylguanosine synthase activity; IDA:BHF-UCL.
DR   GO; GO:0036261; P:7-methylguanosine cap hypermethylation; IDA:BHF-UCL.
DR   GO; GO:0009452; P:7-methylguanosine RNA capping; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0034660; P:ncRNA metabolic process; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0022613; P:ribonucleoprotein complex biogenesis; IC:BHF-UCL.
DR   GO; GO:0071167; P:ribonucleoprotein complex import into nucleus; IC:BHF-UCL.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TGT_HUMAN               Reviewed;         403 AA.
AC   Q9BXR0; Q96BQ4; Q9BXQ9;
DE   RecName: Full=Queuine tRNA-ribosyltransferase;
DE            EC=2.4.2.29;
DE   AltName: Full=Guanine insertion enzyme;
DE   AltName: Full=tRNA-guanine transglycosylase;
GN   Name=QTRT1; Synonyms=TGT, TGUT;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008479; F:queuine tRNA-ribosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0008616; P:queuosine biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006400; P:tRNA modification; TAS:UniProtKB.
//
ID   THA10_HUMAN             Reviewed;         257 AA.
AC   Q9P2Z0; B2R8R0;
DE   RecName: Full=THAP domain-containing protein 10;
GN   Name=THAP10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   THA11_HUMAN             Reviewed;         314 AA.
AC   Q96EK4; A4UCT5; A8K002; O94795;
DE   RecName: Full=THAP domain-containing protein 11;
GN   Name=THAP11; ORFNames=HRIHFB2206;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   THADA_HUMAN             Reviewed;        1953 AA.
AC   Q6YHU6; A8K1V8; B7WNS6; Q3KR04; Q53RC6; Q53TB2; Q6YHU2; Q6ZU38;
AC   Q8IY32; Q8TAU8; Q96I88; Q9BZF7; Q9C096; Q9H6U0; Q9H6W7;
DE   RecName: Full=Thyroid adenoma-associated protein;
DE   AltName: Full=Gene inducing thyroid adenomas protein;
GN   Name=THADA; Synonyms=GITA, KIAA1767;
//
ID   THAP1_HUMAN             Reviewed;         213 AA.
AC   Q9NVV9; A6NCB6; D3DSY5; H9KV49; Q53FQ1; Q6IA99;
DE   RecName: Full=THAP domain-containing protein 1;
GN   Name=THAP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IMP:UniProtKB.
//
ID   THAP2_HUMAN             Reviewed;         228 AA.
AC   Q9H0W7; B2R8P3;
DE   RecName: Full=THAP domain-containing protein 2;
GN   Name=THAP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   THAP3_HUMAN             Reviewed;         239 AA.
AC   Q8WTV1; Q569K1; Q5TH66; Q5TH67; Q8N8T6; Q9BSC7; Q9Y3H2; Q9Y3H3;
DE   RecName: Full=THAP domain-containing protein 3;
GN   Name=THAP3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   THAP4_HUMAN             Reviewed;         577 AA.
AC   Q8WY91; Q53NU7; Q6GRN0; Q6IPJ3; Q9NW26; Q9Y325;
DE   RecName: Full=THAP domain-containing protein 4;
GN   Name=THAP4; ORFNames=CGI-36, PP238;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   THAP5_HUMAN             Reviewed;         395 AA.
AC   Q7Z6K1;
DE   RecName: Full=THAP domain-containing protein 5;
GN   Name=THAP5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0045786; P:negative regulation of cell cycle; IMP:UniProtKB.
//
ID   THAP7_HUMAN             Reviewed;         309 AA.
AC   Q9BT49; B2RD97; D3DX40;
DE   RecName: Full=THAP domain-containing protein 7;
GN   Name=THAP7;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   THAP8_HUMAN             Reviewed;         274 AA.
AC   Q8NA92; Q0P5Z7; Q96M21;
DE   RecName: Full=THAP domain-containing protein 8;
GN   Name=THAP8;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   THAP6_HUMAN             Reviewed;         222 AA.
AC   Q8TBB0; B4E146; Q5HYJ7; Q5JPC6;
DE   RecName: Full=THAP domain-containing protein 6;
GN   Name=THAP6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   THAP9_HUMAN             Reviewed;         903 AA.
AC   Q9H5L6; B3KRE2; Q59AC9;
DE   RecName: Full=DNA transposase THAP9;
DE            EC=2.7.7.-;
DE   AltName: Full=THAP domain-containing protein 9;
DE            Short=hTh9;
GN   Name=THAP9;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IDA:UniProtKB.
DR   GO; GO:0015074; P:DNA integration; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IDA:UniProtKB.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IDA:UniProtKB.
//
ID   THAS_HUMAN              Reviewed;         533 AA.
AC   P24557; B4DJG6; E7EMU9; E7EP08; E7ESB5; O14987; Q16843; Q16844;
AC   Q8IUN1; Q96CN2; Q9GZW4; Q9HD77; Q9HD78; Q9HD79; Q9HD80; Q9HD81;
AC   Q9HD82; Q9HD83; Q9HD84;
DE   RecName: Full=Thromboxane-A synthase;
DE            Short=TXA synthase;
DE            Short=TXS;
DE            EC=5.3.99.5;
DE   AltName: Full=Cytochrome P450 5A1;
GN   Name=TBXAS1; Synonyms=CYP5, CYP5A1;
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0004796; F:thromboxane-A synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019369; P:arachidonic acid metabolic process; TAS:Reactome.
DR   GO; GO:0019371; P:cyclooxygenase pathway; TAS:Reactome.
DR   GO; GO:0006690; P:icosanoid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   THA_HUMAN               Reviewed;         490 AA.
AC   P10827; A8K3B5; P21205; Q8N6A1; Q96H73;
DE   RecName: Full=Thyroid hormone receptor alpha;
DE   AltName: Full=Nuclear receptor subfamily 1 group A member 1;
DE   AltName: Full=V-erbA-related protein 7;
DE            Short=EAR-7;
DE   AltName: Full=c-erbA-1;
DE   AltName: Full=c-erbA-alpha;
GN   Name=THRA; Synonyms=EAR7, ERBA1, NR1A1, THRA1, THRA2;
DR   GuidetoPHARMACOLOGY; 588; -.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0002153; F:steroid receptor RNA activator RNA binding; IEA:Ensembl.
DR   GO; GO:0017025; F:TBP-class protein binding; IDA:UniProtKB.
DR   GO; GO:0070324; F:thyroid hormone binding; IDA:UniProtKB.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0008050; P:female courtship behavior; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:2000143; P:negative regulation of DNA-templated transcription, initiation; IDA:UniProtKB.
DR   GO; GO:0017055; P:negative regulation of RNA polymerase II transcriptional preinitiation complex assembly; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0045925; P:positive regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0010831; P:positive regulation of myotube differentiation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0050994; P:regulation of lipid catabolic process; IEA:Ensembl.
DR   GO; GO:0033032; P:regulation of myeloid cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0002155; P:regulation of thyroid hormone mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0060509; P:Type I pneumocyte differentiation; IEA:Ensembl.
//
ID   THBG_HUMAN              Reviewed;         415 AA.
AC   P05543; D3DUX1;
DE   RecName: Full=Thyroxine-binding globulin;
DE   AltName: Full=Serpin A7;
DE   AltName: Full=T4-binding globulin;
DE   Flags: Precursor;
GN   Name=SERPINA7; Synonyms=TBG;
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0034695; P:response to prostaglandin E; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
//
ID   THB_HUMAN               Reviewed;         461 AA.
AC   P10828; B3KU79; P37243; Q13986; Q3KP35; Q6WGL2; Q9UD41;
DE   RecName: Full=Thyroid hormone receptor beta;
DE   AltName: Full=Nuclear receptor subfamily 1 group A member 2;
DE   AltName: Full=c-erbA-2;
DE   AltName: Full=c-erbA-beta;
GN   Name=THRB; Synonyms=ERBA2, NR1A2, THR1;
DR   GuidetoPHARMACOLOGY; 589; -.
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0070324; F:thyroid hormone binding; IDA:UniProtKB.
DR   GO; GO:0004887; F:thyroid hormone receptor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008050; P:female courtship behavior; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030522; P:intracellular receptor signaling pathway; IDA:GOC.
DR   GO; GO:0007621; P:negative regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0008016; P:regulation of heart contraction; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0060509; P:Type I pneumocyte differentiation; IEA:Ensembl.
//
ID   THEGL_HUMAN             Reviewed;         465 AA.
AC   P0DJG4;
DE   RecName: Full=Testicular haploid expressed gene protein-like;
DE   AltName: Full=Theg spermatid-like protein;
GN   Name=THEGL;
//
ID   THEG_HUMAN              Reviewed;         379 AA.
AC   Q9P2T0; A6NMJ8;
DE   RecName: Full=Testicular haploid expressed gene protein;
DE   AltName: Full=Cancer/testis antigen 56;
DE            Short=CT56;
GN   Name=THEG;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   THEM4_HUMAN             Reviewed;         240 AA.
AC   Q5T1C6; B2RBX2; Q96KR2;
DE   RecName: Full=Acyl-coenzyme A thioesterase THEM4;
DE            Short=Acyl-CoA thioesterase THEM4;
DE            EC=3.1.2.2;
DE   AltName: Full=Carboxyl-terminal modulator protein;
DE   AltName: Full=Thioesterase superfamily member 4;
DE   Flags: Precursor;
GN   Name=THEM4; Synonyms=CTMP;
DR   GO; GO:0016290; F:palmitoyl-CoA hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:1902108; P:regulation of mitochondrial membrane permeability involved in apoptotic process; IMP:UniProtKB.
//
ID   THEM6_HUMAN             Reviewed;         208 AA.
AC   Q8WUY1; B2RDN6; Q8NBN2; Q9NYI2;
DE   RecName: Full=Protein THEM6;
DE   AltName: Full=Mesenchymal stem cell protein DSCD75;
DE   AltName: Full=Thioesterase superfamily member 6;
DE   Flags: Precursor;
GN   Name=THEM6; Synonyms=C8orf55; ORFNames=PSEC0098;
//
ID   THG1_HUMAN              Reviewed;         298 AA.
AC   Q9NWX6; D3DQJ5; Q53G12; Q7L5R3; Q9H0S2;
DE   RecName: Full=Probable tRNA(His) guanylyltransferase;
DE            EC=2.7.7.79;
DE   AltName: Full=Interphase cytoplasmic foci protein 45;
DE   AltName: Full=tRNA-histidine guanylyltransferase;
GN   Name=THG1L; Synonyms=ICF45;
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0005525; F:GTP binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:BHF-UCL.
DR   GO; GO:0000049; F:tRNA binding; TAS:BHF-UCL.
DR   GO; GO:0008193; F:tRNA guanylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0006400; P:tRNA modification; ISS:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IDA:UniProtKB.
//
ID   THIC_HUMAN              Reviewed;         397 AA.
AC   Q9BWD1; E1P5B1; Q16146; Q5TCL7; Q8TDM4;
DE   RecName: Full=Acetyl-CoA acetyltransferase, cytosolic;
DE            EC=2.3.1.9;
DE   AltName: Full=Acetyl-CoA transferase-like protein;
DE   AltName: Full=Cytosolic acetoacetyl-CoA thiolase;
GN   Name=ACAT2; Synonyms=ACTL;
DR   GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; IC:BHF-UCL.
//
ID   THIK_HUMAN              Reviewed;         424 AA.
AC   P09110; G5E935; Q96CA6;
DE   RecName: Full=3-ketoacyl-CoA thiolase, peroxisomal;
DE            EC=2.3.1.16;
DE   AltName: Full=Acetyl-CoA acyltransferase;
DE   AltName: Full=Beta-ketothiolase;
DE   AltName: Full=Peroxisomal 3-oxoacyl-CoA thiolase;
DE   Flags: Precursor;
GN   Name=ACAA1; Synonyms=ACAA, PTHIO;
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016401; F:palmitoyl-CoA oxidase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0036109; P:alpha-linolenic acid metabolic process; TAS:Reactome.
DR   GO; GO:0008206; P:bile acid metabolic process; IMP:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IMP:UniProtKB.
DR   GO; GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0033559; P:unsaturated fatty acid metabolic process; TAS:Reactome.
DR   GO; GO:0000038; P:very long-chain fatty acid metabolic process; IMP:UniProtKB.
//
ID   THIL_HUMAN              Reviewed;         427 AA.
AC   P24752; B2R6H1;
DE   RecName: Full=Acetyl-CoA acetyltransferase, mitochondrial;
DE            EC=2.3.1.9;
DE   AltName: Full=Acetoacetyl-CoA thiolase;
DE   AltName: Full=T2;
DE   Flags: Precursor;
GN   Name=ACAT1; Synonyms=ACAT, MAT;
DR   GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; EXP:Reactome.
DR   GO; GO:0050662; F:coenzyme binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0009083; P:branched-chain amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0046950; P:cellular ketone body metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0046951; P:ketone body biosynthetic process; TAS:Reactome.
DR   GO; GO:0046952; P:ketone body catabolic process; TAS:Reactome.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0072229; P:metanephric proximal convoluted tubule development; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   THIM_HUMAN              Reviewed;         397 AA.
AC   P42765; Q9BUT6;
DE   RecName: Full=3-ketoacyl-CoA thiolase, mitochondrial;
DE            EC=2.3.1.16;
DE   AltName: Full=Acetyl-CoA acyltransferase;
DE   AltName: Full=Beta-ketothiolase;
DE   AltName: Full=Mitochondrial 3-oxoacyl-CoA thiolase;
DE   AltName: Full=T1;
GN   Name=ACAA2;
DR   GO; GO:0003988; F:acetyl-CoA C-acyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006695; P:cholesterol biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:1901029; P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IDA:UniProtKB.
//
ID   THIOM_HUMAN             Reviewed;         166 AA.
AC   Q99757; Q5JZA0; Q6FH60; Q9UH29;
DE   RecName: Full=Thioredoxin, mitochondrial;
DE            Short=MTRX;
DE            Short=Mt-Trx;
DE   AltName: Full=Thioredoxin-2;
DE   Flags: Precursor;
GN   Name=TXN2; Synonyms=TRX2;
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0031669; P:cellular response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
//
ID   THIO_HUMAN              Reviewed;         105 AA.
AC   P10599; B1ALW1; O60744; Q53X69; Q96KI3; Q9UDG5;
DE   RecName: Full=Thioredoxin;
DE            Short=Trx;
DE   AltName: Full=ATL-derived factor;
DE            Short=ADF;
DE   AltName: Full=Surface-associated sulphydryl protein;
DE            Short=SASP;
GN   Name=TXN; Synonyms=TRDX, TRX, TRX1;
DR   GO; GO:0015037; F:peptide disulfide oxidoreductase activity; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0046826; P:negative regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:UniProtKB.
DR   GO; GO:0043388; P:positive regulation of DNA binding; IDA:UniProtKB.
DR   GO; GO:0033158; P:regulation of protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0009314; P:response to radiation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   THMS1_HUMAN             Reviewed;         641 AA.
AC   Q8N1K5; A1L4F0; A8K7N1; B3KT31; B3KW32; B3KY07; Q5T3C4; Q5T3C5;
AC   Q6MZT7;
DE   RecName: Full=Protein THEMIS;
DE   AltName: Full=Thymocyte-expressed molecule involved in selection;
GN   Name=THEMIS; Synonyms=C6orf190, C6orf207;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043383; P:negative T cell selection; ISS:UniProtKB.
DR   GO; GO:0043368; P:positive T cell selection; ISS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
//
ID   THMS2_HUMAN             Reviewed;         643 AA.
AC   Q5TEJ8; A2RTZ3; B4DZT9; B4DZY3; O60560; Q5TEJ1; Q5TEJ9; Q5TEK1;
AC   Q68DP4; Q9BYB6; Q9NS90;
DE   RecName: Full=Protein THEMIS2;
DE   AltName: Full=Induced by contact to basement membrane 1 protein;
DE            Short=Protein ICB-1;
DE   AltName: Full=Thymocyte-expressed molecule involved in selection protein 2;
GN   Name=THEMIS2; Synonyms=C1orf38, ICB1;
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IEA:Ensembl.
//
ID   THNS2_HUMAN             Reviewed;         484 AA.
AC   Q86YJ6; B3KTB1; B5MDX8; B7WPF8; D9ZZB8; Q6P2M7; Q6PI27; Q9NV54;
DE   RecName: Full=Threonine synthase-like 2;
DE            Short=TSH2;
DE            EC=4.2.3.-;
DE   AltName: Full=Secreted osteoclastogenic factor of activated T-cells;
DE            Short=SOFAT;
GN   Name=THNSL2;
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; ISS:BHF-UCL.
DR   GO; GO:0070905; F:serine binding; ISS:BHF-UCL.
DR   GO; GO:0046360; P:2-oxobutyrate biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0016311; P:dephosphorylation; ISS:BHF-UCL.
DR   GO; GO:0009071; P:serine family amino acid catabolic process; ISS:BHF-UCL.
//
ID   THNS1_HUMAN             Reviewed;         743 AA.
AC   Q8IYQ7; B3KWL1; D3DRV3; Q5VV21;
DE   RecName: Full=Threonine synthase-like 1;
DE            Short=TSH1;
GN   Name=THNSL1;
//
ID   THOC1_HUMAN             Reviewed;         657 AA.
AC   Q96FV9; B2RBP6; Q15219; Q64I72; Q64I73;
DE   RecName: Full=THO complex subunit 1;
DE            Short=Tho1;
DE   AltName: Full=Nuclear matrix protein p84;
DE            Short=p84N5;
DE   AltName: Full=hTREX84;
GN   Name=THOC1; Synonyms=HPR1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:2000002; P:negative regulation of DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0048297; P:negative regulation of isotype switching to IgA isotypes; ISS:UniProtKB.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IMP:UniProtKB.
DR   GO; GO:0000018; P:regulation of DNA recombination; IMP:UniProtKB.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IDA:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOC2_HUMAN             Reviewed;        1593 AA.
AC   Q8NI27; A6NM50; Q5JZ12; Q6IN92; Q9H8I6;
DE   RecName: Full=THO complex subunit 2;
DE            Short=Tho2;
DE   AltName: Full=hTREX120;
GN   Name=THOC2; Synonyms=CXorf3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOC3_HUMAN             Reviewed;         351 AA.
AC   Q96J01;
DE   RecName: Full=THO complex subunit 3;
DE            Short=Tho3;
DE   AltName: Full=TEX1 homolog;
DE   AltName: Full=hTREX45;
GN   Name=THOC3;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOC4_HUMAN             Reviewed;         257 AA.
AC   Q86V81; O43672;
DE   RecName: Full=THO complex subunit 4;
DE            Short=Tho4;
DE   AltName: Full=Ally of AML-1 and LEF-1;
DE   AltName: Full=Aly/REF export factor;
DE   AltName: Full=Transcriptional coactivator Aly/REF;
DE   AltName: Full=bZIP-enhancing factor BEF;
GN   Name=ALYREF; Synonyms=ALY, BEF, THOC4;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IMP:UniProtKB.
DR   GO; GO:0000018; P:regulation of DNA recombination; IMP:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOC5_HUMAN             Reviewed;         683 AA.
AC   Q13769; O60839; Q9UPZ5;
DE   RecName: Full=THO complex subunit 5 homolog;
DE   AltName: Full=Functional spliceosome-associated protein 79;
DE            Short=fSAP79;
DE   AltName: Full=NF2/meningioma region protein pK1.3;
DE   AltName: Full=Placental protein 39.2;
DE            Short=PP39.2;
DE   AltName: Full=hTREX90;
GN   Name=THOC5; Synonyms=C22orf19, KIAA0983;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030224; P:monocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:2000002; P:negative regulation of DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0032786; P:positive regulation of DNA-templated transcription, elongation; IMP:UniProtKB.
DR   GO; GO:0060215; P:primitive hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOC6_HUMAN             Reviewed;         341 AA.
AC   Q86W42; B2RA85; Q8NBR1; Q9BTV9;
DE   RecName: Full=THO complex subunit 6 homolog;
DE   AltName: Full=Functional spliceosome-associated protein 35;
DE            Short=fSAP35;
DE   AltName: Full=WD repeat-containing protein 58;
GN   Name=THOC6; Synonyms=WDR58; ORFNames=PSEC0006;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; IMP:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOC7_HUMAN             Reviewed;         204 AA.
AC   Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0;
DE   RecName: Full=THO complex subunit 7 homolog;
DE   AltName: Full=Functional spliceosome-associated protein 24;
DE            Short=fSAP24;
DE   AltName: Full=Ngg1-interacting factor 3-like protein 1-binding protein 1;
DE            Short=NIF3L1-binding protein 1;
DE   AltName: Full=hTREX30;
GN   Name=THOC7; Synonyms=NIF3L1BP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006406; P:mRNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0046784; P:viral mRNA export from host cell nucleus; IDA:UniProtKB.
//
ID   THOP1_HUMAN             Reviewed;         689 AA.
AC   P52888; Q9UCB3;
DE   RecName: Full=Thimet oligopeptidase;
DE            EC=3.4.24.15;
DE   AltName: Full=Endopeptidase 24.15;
DE   AltName: Full=MP78;
GN   Name=THOP1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; TAS:ProtInc.
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006518; P:peptide metabolic process; IEA:Ensembl.
//
ID   THRB_HUMAN              Reviewed;         622 AA.
AC   P00734; B2R7F7; B4E1A7; Q4QZ40; Q53H04; Q53H06; Q69EZ7; Q7Z7P3;
AC   Q9UCA1;
DE   RecName: Full=Prothrombin;
DE            EC=3.4.21.5;
DE   AltName: Full=Coagulation factor II;
DE   Contains:
DE     RecName: Full=Activation peptide fragment 1;
DE   Contains:
DE     RecName: Full=Activation peptide fragment 2;
DE   Contains:
DE     RecName: Full=Thrombin light chain;
DE   Contains:
DE     RecName: Full=Thrombin heavy chain;
DE   Flags: Precursor;
GN   Name=F2;
DR   GuidetoPHARMACOLOGY; 2362; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008083; F:growth factor activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0070053; F:thrombospondin receptor activity; IDA:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0042730; P:fibrinolysis; IDA:UniProtKB.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0048712; P:negative regulation of astrocyte differentiation; IDA:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; TAS:BHF-UCL.
DR   GO; GO:0010544; P:negative regulation of platelet activation; TAS:BHF-UCL.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; IDA:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:1900738; P:positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:Reactome.
DR   GO; GO:0030193; P:regulation of blood coagulation; TAS:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR   GO; GO:0009611; P:response to wounding; IDA:BHF-UCL.
//
ID   THRSP_HUMAN             Reviewed;         146 AA.
AC   Q92748; B2R4W7;
DE   RecName: Full=Thyroid hormone-inducible hepatic protein;
DE   AltName: Full=Spot 14 protein;
DE            Short=S14;
DE            Short=SPOT14;
GN   Name=THRSP;
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0046890; P:regulation of lipid biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0010866; P:regulation of triglyceride biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   THS7A_HUMAN             Reviewed;        1657 AA.
AC   Q9UPZ6;
DE   RecName: Full=Thrombospondin type-1 domain-containing protein 7A;
DE   Flags: Precursor;
GN   Name=THSD7A; Synonyms=KIAA0960;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   THS7B_HUMAN             Reviewed;        1608 AA.
AC   Q9C0I4;
DE   RecName: Full=Thrombospondin type-1 domain-containing protein 7B;
DE   Flags: Precursor;
GN   Name=THSD7B; Synonyms=KIAA1679;
//
ID   THSD1_HUMAN             Reviewed;         852 AA.
AC   Q9NS62; A2A3J3; B2RCF5; Q6P3U1; Q6UXZ2;
DE   RecName: Full=Thrombospondin type-1 domain-containing protein 1;
DE   AltName: Full=Transmembrane molecule with thrombospondin module;
DE   Flags: Precursor;
GN   Name=THSD1; Synonyms=TMTSP; ORFNames=UNQ3010/PRO9769;
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
//
ID   THSD4_HUMAN             Reviewed;        1018 AA.
AC   Q6ZMP0; B2RTY3; B4DR13; Q6MZI3; Q6UXZ8; Q9H8E4;
DE   RecName: Full=Thrombospondin type-1 domain-containing protein 4;
DE   AltName: Full=A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6;
DE            Short=ADAMTS-like protein 6;
DE            Short=ADAMTSL-6;
DE   Flags: Precursor;
GN   Name=THSD4; ORFNames=UNQ9334/PRO34005;
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0048251; P:elastic fiber assembly; IEA:Ensembl.
//
ID   THTM_HUMAN              Reviewed;         297 AA.
AC   P25325; O75750;
DE   RecName: Full=3-mercaptopyruvate sulfurtransferase;
DE            Short=MST;
DE            EC=2.8.1.2;
GN   Name=MPST; Synonyms=TST2;
DR   GO; GO:0016784; F:3-mercaptopyruvate sulfurtransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004792; F:thiosulfate sulfurtransferase activity; TAS:ProtInc.
DR   GO; GO:0009440; P:cyanate catabolic process; TAS:ProtInc.
DR   GO; GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; TAS:ProtInc.
//
ID   THTPA_HUMAN             Reviewed;         230 AA.
AC   Q9BU02; D3DS50; G3V4J3;
DE   RecName: Full=Thiamine-triphosphatase;
DE            Short=ThTPase;
DE            EC=3.6.1.28;
GN   Name=THTPA;
DR   GO; GO:0016787; F:hydrolase activity; TAS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0050333; F:thiamin-triphosphatase activity; IDA:UniProtKB.
DR   GO; GO:0016311; P:dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0042357; P:thiamine diphosphate metabolic process; ISS:UniProtKB.
DR   GO; GO:0006772; P:thiamine metabolic process; TAS:UniProtKB.
DR   GO; GO:0042723; P:thiamine-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   THTR_HUMAN              Reviewed;         297 AA.
AC   Q16762; B3KRM1; Q6IB06;
DE   RecName: Full=Thiosulfate sulfurtransferase;
DE            EC=2.8.1.1;
DE   AltName: Full=Rhodanese;
GN   Name=TST;
DR   GO; GO:0008097; F:5S rRNA binding; IDA:UniProtKB.
DR   GO; GO:0004792; F:thiosulfate sulfurtransferase activity; TAS:ProtInc.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0009440; P:cyanate catabolic process; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProt.
DR   GO; GO:0035928; P:rRNA import into mitochondrion; IMP:UniProtKB.
DR   GO; GO:0051029; P:rRNA transport; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0070221; P:sulfide oxidation, using sulfide:quinone oxidoreductase; TAS:Reactome.
DR   GO; GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.
DR   GO; GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome.
//
ID   THUM1_HUMAN             Reviewed;         353 AA.
AC   Q9NXG2; Q9BWC3;
DE   RecName: Full=THUMP domain-containing protein 1;
GN   Name=THUMPD1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   THUM2_HUMAN             Reviewed;         503 AA.
AC   Q9BTF0; A8K7I7; Q53TT8; Q53TV0;
DE   RecName: Full=THUMP domain-containing protein 2;
GN   Name=THUMPD2; Synonyms=C2orf8;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   THUM3_HUMAN             Reviewed;         507 AA.
AC   Q9BV44; Q9H8V6; Q9NVC1; Q9UFS3;
DE   RecName: Full=THUMP domain-containing protein 3;
GN   Name=THUMPD3;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   THY1_HUMAN              Reviewed;         161 AA.
AC   P04216; Q16008; Q9NSP1;
DE   RecName: Full=Thy-1 membrane glycoprotein;
DE   AltName: Full=CDw90;
DE   AltName: Full=Thy-1 antigen;
DE   AltName: CD_antigen=CD90;
DE   Flags: Precursor;
GN   Name=THY1;
DR   GO; GO:0034235; F:GPI anchor binding; ISS:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; ISS:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.
DR   GO; GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.
DR   GO; GO:0046549; P:retinal cone cell development; ISS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
//
ID   THYG_HUMAN              Reviewed;        2768 AA.
AC   P01266; O15274; O43899; Q15593; Q15948; Q9NYR1; Q9NYR2; Q9UMZ0;
AC   Q9UNY3;
DE   RecName: Full=Thyroglobulin;
DE            Short=Tg;
DE   Flags: Precursor;
GN   Name=TG;
DR   GO; GO:0042446; P:hormone biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0015705; P:iodide transport; IEA:Ensembl.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0030878; P:thyroid gland development; IEP:UniProtKB.
DR   GO; GO:0006590; P:thyroid hormone generation; IBA:RefGenome.
//
ID   THYN1_HUMAN             Reviewed;         225 AA.
AC   Q9P016; Q567Q2; Q9H3L4; Q9HC20;
DE   RecName: Full=Thymocyte nuclear protein 1;
DE   AltName: Full=Thymocyte protein Thy28;
GN   Name=THYN1; Synonyms=THY28; ORFNames=HSPC144, MDS012, My0054;
//
ID   TI17A_HUMAN             Reviewed;         171 AA.
AC   Q99595; B2RDM5; Q9BWF5;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-A;
DE   AltName: Full=Inner membrane preprotein translocase Tim17a;
GN   Name=TIMM17A; Synonyms=MIMT17, TIM17, TIM17A, TIMM17;
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TI17B_HUMAN             Reviewed;         172 AA.
AC   O60830; A8K2E2; J3KPV3; Q9UJV0;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B;
GN   Name=TIMM17B; Synonyms=TIM17B; ORFNames=JM3;
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TI23B_HUMAN             Reviewed;         257 AA.
AC   Q5SRD1; Q5SRD2;
DE   RecName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B;
GN   Name=TIMM23B;
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   TIA1_HUMAN              Reviewed;         386 AA.
AC   P31483; Q53SS9;
DE   RecName: Full=Nucleolysin TIA-1 isoform p40;
DE   AltName: Full=RNA-binding protein TIA-1;
DE   AltName: Full=T-cell-restricted intracellular antigen-1;
DE            Short=TIA-1;
DE   AltName: Full=p40-TIA-1;
GN   Name=TIA1;
DR   GO; GO:0017091; F:AU-rich element binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0008143; F:poly(A) binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0042036; P:negative regulation of cytokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:Ensembl.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
//
ID   TIAF1_HUMAN             Reviewed;         115 AA.
AC   O95411; A2RRE2; Q6PEG2;
DE   RecName: Full=TGFB1-induced anti-apoptotic factor 1;
DE   AltName: Full=12 kDa TGF-beta-1-induced antiapoptotic factor;
GN   Name=TIAF1;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
//
ID   TIAM2_HUMAN             Reviewed;        1701 AA.
AC   Q8IVF5; B2RP56; C9JZV2; Q6NXN9; Q6ZUP9; Q9UFG6; Q9UKV9; Q9UKW0;
DE   RecName: Full=T-lymphoma invasion and metastasis-inducing protein 2;
DE            Short=TIAM-2;
DE   AltName: Full=SIF and TIAM1-like exchange factor;
GN   Name=TIAM2; Synonyms=KIAA2016, STEF;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TIAM1_HUMAN             Reviewed;        1591 AA.
AC   Q13009; Q17RT7;
DE   RecName: Full=T-lymphoma invasion and metastasis-inducing protein 1;
DE            Short=TIAM-1;
GN   Name=TIAM1;
DR   GO; GO:0005543; F:phospholipid binding; IEA:Ensembl.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IMP:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:InterPro.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0016601; P:Rac protein signal transduction; IMP:UniProtKB.
DR   GO; GO:0032314; P:regulation of Rac GTPase activity; IMP:GOC.
DR   GO; GO:0032319; P:regulation of Rho GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   TIAR_HUMAN              Reviewed;         375 AA.
AC   Q01085; A8K3T0; A8K4L9;
DE   RecName: Full=Nucleolysin TIAR;
DE   AltName: Full=TIA-1-related protein;
GN   Name=TIAL1;
DR   GO; GO:0017091; F:AU-rich element binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0017145; P:stem cell division; IEA:Ensembl.
//
ID   TICN1_HUMAN             Reviewed;         439 AA.
AC   Q08629; B3KSW3; Q59EW0; Q8N630; Q9UCL8;
DE   RecName: Full=Testican-1;
DE   AltName: Full=Protein SPOCK;
DE   Flags: Precursor;
GN   Name=SPOCK1; Synonyms=SPOCK, TIC1, TICN1;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; ISS:UniProtKB.
DR   GO; GO:0001764; P:neuron migration; ISS:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   TICN2_HUMAN             Reviewed;         424 AA.
AC   Q92563; C9J767; Q6UW87;
DE   RecName: Full=Testican-2;
DE   AltName: Full=SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2;
DE   Flags: Precursor;
GN   Name=SPOCK2; Synonyms=KIAA0275, TICN2; ORFNames=UNQ269/PRO306;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0045595; P:regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0007416; P:synapse assembly; NAS:UniProtKB.
//
ID   TICN3_HUMAN             Reviewed;         436 AA.
AC   Q9BQ16; B2R7M7; B3KR67; B4DGK5; B4DHB4; B4DHV3; B4DI46; B4DJY3;
AC   E7EP61; F5H099; O75705; Q6UW53; Q96Q26;
DE   RecName: Full=Testican-3;
DE   AltName: Full=SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3;
DE   Flags: Precursor;
GN   Name=SPOCK3; Synonyms=TICN3; ORFNames=UNQ409/PRO771;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0019800; P:peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   TICRR_HUMAN             Reviewed;        1910 AA.
AC   Q7Z2Z1; B2RE07; B3KVV9; D3IUT4; Q8N4X8; Q8NCH6; Q9BU55;
DE   RecName: Full=Treslin;
DE   AltName: Full=TopBP1-interacting checkpoint and replication regulator;
DE   AltName: Full=TopBP1-interacting, replication-stimulating protein;
GN   Name=TICRR; Synonyms=C15orf42;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; ISS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; ISS:UniProtKB.
DR   GO; GO:0001731; P:formation of translation preinitiation complex; ISS:UniProtKB.
DR   GO; GO:0033314; P:mitotic DNA replication checkpoint; ISS:UniProtKB.
DR   GO; GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
//
ID   TIDC1_HUMAN             Reviewed;         285 AA.
AC   Q9NPL8; D3DN81; Q6IAJ7; Q6UWU6; Q9NPR3; Q9NPS5; Q9P0Y6;
DE   RecName: Full=Complex I assembly factor TIMMDC1, mitochondrial;
DE   AltName: Full=Protein M5-14;
DE   AltName: Full=Translocase of inner mitochondrial membrane domain-containing protein 1;
GN   Name=TIMMDC1; Synonyms=C3orf1; ORFNames=UNQ247/PRO284;
//
ID   TIE1_HUMAN              Reviewed;        1138 AA.
AC   P35590; B5A949; B5A950;
DE   RecName: Full=Tyrosine-protein kinase receptor Tie-1;
DE            EC=2.7.10.1;
DE   Flags: Precursor;
GN   Name=TIE1; Synonyms=TIE;
DR   GuidetoPHARMACOLOGY; 1841; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007498; P:mesoderm development; TAS:ProtInc.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0045026; P:plasma membrane fusion; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   TIE2_HUMAN              Reviewed;        1124 AA.
AC   Q02763; A8K6W0; B4DH20; B4DHD3; D3DRK5; E7EWI2; Q5TCU2; Q8IV34;
DE   RecName: Full=Angiopoietin-1 receptor;
DE            EC=2.7.10.1;
DE   AltName: Full=Endothelial tyrosine kinase;
DE   AltName: Full=Tunica interna endothelial cell kinase;
DE   AltName: Full=Tyrosine kinase with Ig and EGF homology domains-2;
DE   AltName: Full=Tyrosine-protein kinase receptor TEK;
DE   AltName: Full=Tyrosine-protein kinase receptor TIE-2;
DE            Short=hTIE2;
DE   AltName: Full=p140 TEK;
DE   AltName: CD_antigen=CD202b;
DE   Flags: Precursor;
GN   Name=TEK; Synonyms=TIE2, VMCM, VMCM1;
DR   GuidetoPHARMACOLOGY; 1842; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; TAS:ProtInc.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; TAS:UniProtKB.
DR   GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
DR   GO; GO:0001935; P:endothelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0072012; P:glomerulus vasculature development; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0060347; P:heart trabecula formation; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; TAS:UniProtKB.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000251; P:positive regulation of actin cytoskeleton reorganization; IMP:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; TAS:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB.
DR   GO; GO:1902533; P:positive regulation of intracellular signal transduction; IMP:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:2000351; P:regulation of endothelial cell apoptotic process; TAS:UniProtKB.
DR   GO; GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:UniProtKB.
DR   GO; GO:0043114; P:regulation of vascular permeability; TAS:UniProtKB.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002040; P:sprouting angiogenesis; IMP:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
DR   GO; GO:0048014; P:Tie signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IDA:UniProtKB.
//
ID   TIF1A_HUMAN             Reviewed;        1050 AA.
AC   O15164; A4D1R7; A4D1R8; O95854;
DE   RecName: Full=Transcription intermediary factor 1-alpha;
DE            Short=TIF1-alpha;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ubiquitin-protein ligase TRIM24;
DE   AltName: Full=RING finger protein 82;
DE   AltName: Full=Tripartite motif-containing protein 24;
GN   Name=TRIM24; Synonyms=RNF82, TIF1, TIF1A;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0034056; F:estrogen response element binding; IDA:UniProtKB.
DR   GO; GO:0070577; F:lysine-acetylated histone binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0030163; P:protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IMP:UniProtKB.
DR   GO; GO:1901796; P:regulation of signal transduction by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0070562; P:regulation of vitamin D receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TIF1B_HUMAN             Reviewed;         835 AA.
AC   Q13263; O00677; Q7Z632; Q93040; Q96IM1;
DE   RecName: Full=Transcription intermediary factor 1-beta;
DE            Short=TIF1-beta;
DE   AltName: Full=E3 SUMO-protein ligase TRIM28;
DE            EC=6.3.2.-;
DE   AltName: Full=KRAB-associated protein 1;
DE            Short=KAP-1;
DE   AltName: Full=KRAB-interacting protein 1;
DE            Short=KRIP-1;
DE   AltName: Full=Nuclear corepressor KAP-1;
DE   AltName: Full=RING finger protein 96;
DE   AltName: Full=Tripartite motif-containing protein 28;
GN   Name=TRIM28; Synonyms=KAP1, RNF96, TIF1B;
DR   GO; GO:0070087; F:chromo shadow domain binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0035851; F:Krueppel-associated box domain binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IEA:Ensembl.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0060028; P:convergent extension involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0060669; P:embryonic placenta morphogenesis; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; ISS:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0042993; P:positive regulation of transcription factor import into nucleus; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:HGNC.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IDA:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:GOC.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   TIFAB_HUMAN             Reviewed;         161 AA.
AC   Q6ZNK6; Q5H8A9;
DE   RecName: Full=TRAF-interacting protein with FHA domain-containing protein B;
DE   AltName: Full=TIFA-like protein;
GN   Name=TIFAB;
//
ID   TIFA_HUMAN              Reviewed;         184 AA.
AC   Q96CG3;
DE   RecName: Full=TRAF-interacting protein with FHA domain-containing protein A;
DE   AltName: Full=Putative MAPK-activating protein PM14;
DE   AltName: Full=Putative NF-kappa-B-activating protein 20;
DE   AltName: Full=TRAF2-binding protein;
GN   Name=TIFA; Synonyms=T2BP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
//
ID   TIG1_HUMAN              Reviewed;         294 AA.
AC   P49788; Q8N1D7;
DE   RecName: Full=Retinoic acid receptor responder protein 1;
DE   AltName: Full=RAR-responsive protein TIG1;
DE   AltName: Full=Tazarotene-induced gene 1 protein;
GN   Name=RARRES1; Synonyms=TIG1;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
//
ID   TIGAR_HUMAN             Reviewed;         270 AA.
AC   Q9NQ88; B2R840;
DE   RecName: Full=Fructose-2,6-bisphosphatase TIGAR;
DE            EC=3.1.3.46;
DE   AltName: Full=TP53-induced glycolysis and apoptosis regulator;
GN   Name=TIGAR; Synonyms=C12orf5;
DR   GO; GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:1901525; P:negative regulation of macromitophagy; IEA:Ensembl.
DR   GO; GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0010666; P:positive regulation of cardiac muscle cell apoptotic process; IEA:Ensembl.
//
ID   TIGD1_HUMAN             Reviewed;         591 AA.
AC   Q96MW7; Q6P4D2; Q6PIF9;
DE   RecName: Full=Tigger transposable element-derived protein 1;
GN   Name=TIGD1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGD3_HUMAN             Reviewed;         471 AA.
AC   Q6B0B8;
DE   RecName: Full=Tigger transposable element-derived protein 3;
GN   Name=TIGD3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGD2_HUMAN             Reviewed;         525 AA.
AC   Q4W5G0;
DE   RecName: Full=Tigger transposable element-derived protein 2;
GN   Name=TIGD2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGD4_HUMAN             Reviewed;         512 AA.
AC   Q8IY51; Q96LP5;
DE   RecName: Full=Tigger transposable element-derived protein 4;
GN   Name=TIGD4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGD5_HUMAN             Reviewed;         642 AA.
AC   Q53EQ6; E7EWS2; Q6NT83; Q8N5A1; Q96JW8;
DE   RecName: Full=Tigger transposable element-derived protein 5;
GN   Name=TIGD5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGD6_HUMAN             Reviewed;         521 AA.
AC   Q17RP2; B3KTZ8; Q96MQ4; Q9H0X7;
DE   RecName: Full=Tigger transposable element-derived protein 6;
GN   Name=TIGD6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGD7_HUMAN             Reviewed;         549 AA.
AC   Q6NT04; Q9BXZ0;
DE   RecName: Full=Tigger transposable element-derived protein 7;
GN   Name=TIGD7;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TIGIT_HUMAN             Reviewed;         244 AA.
AC   Q495A1; Q495A3; Q5JPD8; Q6MZS2; Q8N877;
DE   RecName: Full=T-cell immunoreceptor with Ig and ITIM domains;
DE   AltName: Full=V-set and immunoglobulin domain-containing protein 9;
DE   AltName: Full=V-set and transmembrane domain-containing protein 3;
DE   Flags: Precursor;
GN   Name=TIGIT; Synonyms=VSIG9, VSTM3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:MGI.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IMP:UniProtKB.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IMP:UniProtKB.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IMP:UniProtKB.
//
ID   TIKI1_HUMAN             Reviewed;         505 AA.
AC   Q86V40; B4DKK8; I6UMB9;
DE   RecName: Full=Metalloprotease TIKI1;
DE            EC=3.4.-.-;
DE   AltName: Full=TRAB domain-containing protein 2A;
DE   Flags: Precursor;
GN   Name=TRABD2A; Synonyms=C2orf89, TIKI1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0017147; F:Wnt-protein binding; IDA:UniProtKB.
DR   GO; GO:0060322; P:head development; ISS:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0018158; P:protein oxidation; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TIKI2_HUMAN             Reviewed;         517 AA.
AC   A6NFA1; I6U4Y0;
DE   RecName: Full=Metalloprotease TIKI2;
DE            EC=3.4.-.-;
DE   AltName: Full=Heart, kidney and adipose-enriched transmembrane protein homolog;
DE   AltName: Full=TRAB domain-containing protein 2B;
DE   Flags: Precursor;
GN   Name=TRABD2B; Synonyms=HKAT, TIKI2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017147; F:Wnt-protein binding; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0018158; P:protein oxidation; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TILB_HUMAN              Reviewed;         466 AA.
AC   Q86X45; Q13648; Q4G183;
DE   RecName: Full=Protein tilB homolog;
DE   AltName: Full=Leucine-rich repeat-containing protein 6;
DE   AltName: Full=Leucine-rich testis-specific protein;
DE   AltName: Full=Testis-specific leucine-rich repeat protein;
GN   Name=LRRC6; Synonyms=LRTP, TSLRP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003341; P:cilium movement; IMP:BHF-UCL.
DR   GO; GO:0060287; P:epithelial cilium movement involved in determination of left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0036159; P:inner dynein arm assembly; IMP:BHF-UCL.
DR   GO; GO:0008584; P:male gonad development; ISS:BHF-UCL.
DR   GO; GO:0044458; P:motile cilium assembly; IMP:BHF-UCL.
DR   GO; GO:0036158; P:outer dynein arm assembly; IMP:BHF-UCL.
DR   GO; GO:0061458; P:reproductive system development; IMP:BHF-UCL.
DR   GO; GO:0030317; P:sperm motility; IMP:BHF-UCL.
//
ID   TIM10_HUMAN             Reviewed;          90 AA.
AC   P62072; A8K136; Q9WV99; Q9WVA0; Q9Y5J8;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim10;
GN   Name=TIMM10; Synonyms=TIM10;
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; IDA:BHF-UCL.
DR   GO; GO:0045039; P:protein import into mitochondrial inner membrane; IDA:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:UniProtKB.
//
ID   TIM13_HUMAN             Reviewed;          95 AA.
AC   Q9Y5L4; P62206; Q9UHL8; Q9WTL1;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim13;
GN   Name=TIMM13; Synonyms=TIM13B, TIMM13A, TIMM13B;
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; TAS:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   TIM14_HUMAN             Reviewed;         116 AA.
AC   Q96DA6; B2R4B1; C9JBV1;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit TIM14;
DE   AltName: Full=DnaJ homolog subfamily C member 19;
GN   Name=DNAJC19; Synonyms=TIM14, TIMM14;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0048806; P:genitalia development; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; NAS:UniProtKB.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   TIM16_HUMAN             Reviewed;         125 AA.
AC   Q9Y3D7; Q6I9Z3; Q9H5X3;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit TIM16;
DE   AltName: Full=Mitochondria-associated granulocyte macrophage CSF-signaling molecule;
DE   AltName: Full=Presequence translocated-associated motor subunit PAM16;
GN   Name=PAM16; Synonyms=MAGMAS, TIM16, TIMM16; ORFNames=CGI-136;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TIM21_HUMAN             Reviewed;         248 AA.
AC   Q9BVV7; Q9P010;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim21;
DE   AltName: Full=TIM21-like protein, mitochondrial;
DE   Flags: Precursor;
GN   Name=TIMM21; Synonyms=C18orf55, TIM21; ORFNames=HSPC154;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:UniProtKB.
DR   GO; GO:0033617; P:mitochondrial respiratory chain complex IV assembly; IMP:UniProtKB.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IMP:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TIM22_HUMAN             Reviewed;         194 AA.
AC   Q9Y584; Q9NWI8;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim22;
DE   AltName: Full=Testis-expressed sequence 4;
GN   Name=TIMM22; Synonyms=TEX4, TIM22;
DR   GO; GO:0015266; F:protein channel activity; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0045039; P:protein import into mitochondrial inner membrane; TAS:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TIM23_HUMAN             Reviewed;         209 AA.
AC   O14925; Q53FF8; Q5T1E6; Q6P5S5;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim23;
GN   Name=TIMM23; Synonyms=TIM23;
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TIM44_HUMAN             Reviewed;         452 AA.
AC   O43615; A8K0R9; D6W664; Q8N193;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit TIM44;
DE   Flags: Precursor;
GN   Name=TIMM44; Synonyms=MIMT44, TIM44;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TIM50_HUMAN             Reviewed;         353 AA.
AC   Q3ZCQ8; Q330K1; Q6QA00; Q96FJ5; Q96GY2; Q9H370;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit TIM50;
DE   Flags: Precursor;
GN   Name=TIMM50; Synonyms=TIM50; ORFNames=PRO1512;
DR   GO; GO:0005134; F:interleukin-2 receptor binding; IDA:MGI.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IDA:MGI.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007006; P:mitochondrial membrane organization; IMP:UniProtKB.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; IDA:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
DR   GO; GO:0001836; P:release of cytochrome c from mitochondria; IDA:MGI.
//
ID   TIM8A_HUMAN             Reviewed;          97 AA.
AC   O60220; B2R5A6; Q6IRW6;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim8 A;
DE   AltName: Full=Deafness dystonia protein 1;
DE   AltName: Full=X-linked deafness dystonia protein;
GN   Name=TIMM8A; Synonyms=DDP, DDP1, TIM8A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; TAS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TIM8B_HUMAN             Reviewed;          83 AA.
AC   Q9Y5J9; B0YJA5; Q3KQS9; Q9UN04;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim8 B;
DE   AltName: Full=DDP-like protein;
DE   AltName: Full=Deafness dystonia protein 2;
GN   Name=TIMM8B; Synonyms=DDP2, DDPL, TIM8B;
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; TAS:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   TIM9_HUMAN              Reviewed;          89 AA.
AC   Q9Y5J7; B2R584;
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit Tim9;
GN   Name=TIMM9; Synonyms=TIM9, TIM9A, TIMM9A;
DR   GO; GO:0051087; F:chaperone binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; IDA:BHF-UCL.
DR   GO; GO:0045039; P:protein import into mitochondrial inner membrane; IDA:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   TIMD4_HUMAN             Reviewed;         378 AA.
AC   Q96H15; B5MCL9;
DE   RecName: Full=T-cell immunoglobulin and mucin domain-containing protein 4;
DE            Short=TIMD-4;
DE   AltName: Full=T-cell immunoglobulin mucin receptor 4;
DE            Short=TIM-4;
DE   AltName: Full=T-cell membrane protein 4;
DE   Flags: Precursor;
GN   Name=TIMD4; Synonyms=TIM4;
//
ID   TIMP1_HUMAN             Reviewed;         207 AA.
AC   P01033; Q14252; Q9UCU1;
DE   RecName: Full=Metalloproteinase inhibitor 1;
DE   AltName: Full=Erythroid-potentiating activity;
DE            Short=EPA;
DE   AltName: Full=Fibroblast collagenase inhibitor;
DE            Short=Collagenase inhibitor;
DE   AltName: Full=Tissue inhibitor of metalloproteinases 1;
DE            Short=TIMP-1;
DE   Flags: Precursor;
GN   Name=TIMP1; Synonyms=CLGI, TIMP;
DR   GO; GO:0005125; F:cytokine activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0043249; P:erythrocyte maturation; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IDA:UniProtKB.
DR   GO; GO:0048553; P:negative regulation of metalloenzyme activity; IDA:UniProtKB.
DR   GO; GO:1901164; P:negative regulation of trophoblast cell migration; IMP:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2001044; P:regulation of integrin-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
//
ID   TIMP2_HUMAN             Reviewed;         220 AA.
AC   P16035; Q16121; Q93006; Q9UDF7;
DE   RecName: Full=Metalloproteinase inhibitor 2;
DE   AltName: Full=CSC-21K;
DE   AltName: Full=Tissue inhibitor of metalloproteinases 2;
DE            Short=TIMP-2;
DE   Flags: Precursor;
GN   Name=TIMP2;
DR   GO; GO:0008047; F:enzyme activator activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IEA:Ensembl.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0045762; P:positive regulation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0032487; P:regulation of Rap protein signal transduction; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
//
ID   TIMP3_HUMAN             Reviewed;         211 AA.
AC   P35625; B2RBY9; Q5THV4; Q9UC74; Q9UGS2;
DE   RecName: Full=Metalloproteinase inhibitor 3;
DE   AltName: Full=Protein MIG-5;
DE   AltName: Full=Tissue inhibitor of metalloproteinases 3;
DE            Short=TIMP-3;
DE   Flags: Precursor;
GN   Name=TIMP3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071310; P:cellular response to organic substance; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0051045; P:negative regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   TIMP4_HUMAN             Reviewed;         224 AA.
AC   Q99727; B2R7K6;
DE   RecName: Full=Metalloproteinase inhibitor 4;
DE   AltName: Full=Tissue inhibitor of metalloproteinases 4;
DE            Short=TIMP-4;
DE   Flags: Precursor;
GN   Name=TIMP4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; NAS:GOC.
DR   GO; GO:0042698; P:ovulation cycle; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
//
ID   TIM_HUMAN               Reviewed;        1208 AA.
AC   Q9UNS1; B2ZAV0; O94802; Q86VM1; Q8IWH3;
DE   RecName: Full=Protein timeless homolog;
DE            Short=hTIM;
GN   Name=TIMELESS; Synonyms=TIM, TIM1, TIMELESS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0044770; P:cell cycle phase transition; IMP:BHF-UCL.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB.
DR   GO; GO:0009582; P:detection of abiotic stimulus; TAS:ProtInc.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009628; P:response to abiotic stimulus; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TINAG_HUMAN             Reviewed;         476 AA.
AC   Q9UJW2; Q5T467; Q9UJW1; Q9ULZ4;
DE   RecName: Full=Tubulointerstitial nephritis antigen;
DE            Short=TIN-Ag;
GN   Name=TINAG;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; TAS:ProtInc.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   TINAL_HUMAN             Reviewed;         467 AA.
AC   Q9GZM7; A8K9Q5; B4DPK6; D3DPN8; Q8TEJ9; Q8WZ23; Q96GZ4; Q96JW3;
DE   RecName: Full=Tubulointerstitial nephritis antigen-like;
DE   AltName: Full=Glucocorticoid-inducible protein 5;
DE   AltName: Full=Oxidized LDL-responsive gene 2 protein;
DE            Short=OLRG-2;
DE   AltName: Full=Tubulointerstitial nephritis antigen-related protein;
DE            Short=TIN Ag-related protein;
DE            Short=TIN-Ag-RP;
DE   Flags: Precursor;
GN   Name=TINAGL1; Synonyms=GIS5, LCN7, OLRG2, TINAGL;
GN   ORFNames=PP6614, PSEC0088, UNQ204/PRO230;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; NAS:UniProtKB.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0016197; P:endosomal transport; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
//
ID   TINF2_HUMAN             Reviewed;         451 AA.
AC   Q9BSI4; B3W5Q7; Q9H904; Q9UHC2;
DE   RecName: Full=TERF1-interacting nuclear factor 2;
DE   AltName: Full=TRF1-interacting nuclear protein 2;
GN   Name=TINF2; Synonyms=TIN2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0010836; P:negative regulation of protein ADP-ribosylation; IGI:BHF-UCL.
DR   GO; GO:0032211; P:negative regulation of telomere maintenance via telomerase; IGI:BHF-UCL.
DR   GO; GO:0032206; P:positive regulation of telomere maintenance; IMP:BHF-UCL.
DR   GO; GO:0034502; P:protein localization to chromosome; IMP:BHF-UCL.
DR   GO; GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.
DR   GO; GO:0032202; P:telomere assembly; IMP:BHF-UCL.
DR   GO; GO:0000723; P:telomere maintenance; TAS:Reactome.
DR   GO; GO:0010833; P:telomere maintenance via telomere lengthening; IMP:BHF-UCL.
//
ID   TIP39_HUMAN             Reviewed;         100 AA.
AC   Q96A98; Q96DJ4;
DE   RecName: Full=Tuberoinfundibular peptide of 39 residues;
DE            Short=TIP39;
DE   AltName: Full=Parathyroid hormone 2;
DE   Flags: Precursor;
GN   Name=PTH2; Synonyms=TIP39, TIPF39;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
//
ID   TIPIN_HUMAN             Reviewed;         301 AA.
AC   Q9BVW5; B2CW64; Q9NWZ6;
DE   RecName: Full=TIMELESS-interacting protein;
GN   Name=TIPIN;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0044770; P:cell cycle phase transition; IMP:BHF-UCL.
DR   GO; GO:0000076; P:DNA replication checkpoint; IMP:HGNC.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IMP:HGNC.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:HGNC.
DR   GO; GO:0033262; P:regulation of nuclear cell cycle DNA replication; TAS:HGNC.
DR   GO; GO:0048478; P:replication fork protection; IEA:InterPro.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
//
ID   TIPRL_HUMAN             Reviewed;         272 AA.
AC   O75663; B2R8V3; Q5HYB2; Q8IZ86;
DE   RecName: Full=TIP41-like protein;
DE   AltName: Full=Putative MAPK-activating protein PM10;
DE   AltName: Full=Type 2A-interacting protein;
DE            Short=TIP;
GN   Name=TIPRL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0034048; P:negative regulation of protein phosphatase type 2A activity; IDA:UniProtKB.
//
ID   TIP_HUMAN               Reviewed;         612 AA.
AC   Q8TB96; Q96SR4; Q9BRE2; Q9H2V9;
DE   RecName: Full=T-cell immunomodulatory protein;
DE            Short=Protein TIP;
DE   AltName: Full=Integrin-alpha FG-GAP repeat-containing protein 1;
DE   Flags: Precursor;
GN   Name=ITFG1; Synonyms=TIP; ORFNames=CDA08;
//
ID   TIRAP_HUMAN             Reviewed;         221 AA.
AC   P58753; B3KW65; Q56UH9; Q56UI0; Q8N5E5;
DE   RecName: Full=Toll/interleukin-1 receptor domain-containing adapter protein;
DE            Short=TIR domain-containing adapter protein;
DE   AltName: Full=Adaptor protein Wyatt;
DE   AltName: Full=MyD88 adapter-like protein;
DE            Short=MyD88-2;
GN   Name=TIRAP; Synonyms=MAL;
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030674; F:protein binding, bridging; NAS:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.
DR   GO; GO:0035663; F:Toll-like receptor 2 binding; IPI:BHF-UCL.
DR   GO; GO:0035662; F:Toll-like receptor 4 binding; IPI:BHF-UCL.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:BHF-UCL.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0071221; P:cellular response to bacterial lipopeptide; ISS:BHF-UCL.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; ISS:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; ISS:BHF-UCL.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0030099; P:myeloid cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; ISS:BHF-UCL.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000340; P:positive regulation of chemokine (C-X-C motif) ligand 1 production; ISS:BHF-UCL.
DR   GO; GO:2000343; P:positive regulation of chemokine (C-X-C motif) ligand 2 production; ISS:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032738; P:positive regulation of interleukin-15 production; IDA:BHF-UCL.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IMP:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0090073; P:positive regulation of protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0034137; P:positive regulation of toll-like receptor 2 signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0034141; P:positive regulation of toll-like receptor 3 signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.
DR   GO; GO:0032648; P:regulation of interferon-beta production; ISS:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0035665; P:TIRAP-dependent toll-like receptor 4 signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   TISB_HUMAN              Reviewed;         338 AA.
AC   Q07352; Q13851;
DE   RecName: Full=Zinc finger protein 36, C3H1 type-like 1;
DE   AltName: Full=Butyrate response factor 1;
DE   AltName: Full=EGF-response factor 1;
DE            Short=ERF-1;
DE   AltName: Full=Protein TIS11B;
GN   Name=ZFP36L1; Synonyms=BERG36, BRF1, ERF1, RNF162B, TIS11B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IEA:Ensembl.
DR   GO; GO:0043488; P:regulation of mRNA stability; IDA:MGI.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:GOC.
DR   GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   TISD_HUMAN              Reviewed;         494 AA.
AC   P47974; Q53TB4; Q9BSJ3;
DE   RecName: Full=Zinc finger protein 36, C3H1 type-like 2;
DE            Short=ZFP36-like 2;
DE   AltName: Full=Butyrate response factor 2;
DE   AltName: Full=EGF-response factor 2;
DE            Short=ERF-2;
DE   AltName: Full=Protein TIS11D;
GN   Name=ZFP36L2; Synonyms=BRF2, ERF2, RNF162C, TIS11D;
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0060216; P:definitive hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0030097; P:hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.
DR   GO; GO:2000737; P:negative regulation of stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IEA:Ensembl.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0048103; P:somatic stem cell division; ISS:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
//
ID   TISR_HUMAN              Reviewed;          44 AA.
AC   Q9Y5M6; Q4G0F9;
DE   RecName: Full=Oculomedin;
DE   AltName: Full=Trabecular meshwork-inducible stretch response protein;
DE            Short=TISR;
GN   Name=OCLM;
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   TITIN_HUMAN             Reviewed;       34350 AA.
AC   Q8WZ42; A6NKB1; E7EQE6; E7ET18; K7ENY1; Q10465; Q10466; Q15598;
AC   Q2XUS3; Q32Q60; Q4U1Z6; Q4ZG20; Q6NSG0; Q6PDB1; Q6PJP0; Q7KYM2;
AC   Q7KYN4; Q7KYN5; Q7LDM3; Q7Z2X3; Q8TCG8; Q8WZ51; Q8WZ52; Q8WZ53;
AC   Q8WZB3; Q92761; Q92762; Q9UD97; Q9UP84; Q9Y6L9;
DE   RecName: Full=Titin;
DE            EC=2.7.11.1;
DE   AltName: Full=Connectin;
DE   AltName: Full=Rhabdomyosarcoma antigen MU-RMS-40.14;
GN   Name=TTN;
DR   GO; GO:0051015; F:actin filament binding; IDA:BHF-UCL.
DR   GO; GO:0042805; F:actinin binding; IDA:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0005516; F:calmodulin binding; TAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0051371; F:muscle alpha-actinin binding; IPI:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0043621; F:protein self-association; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:UniProtKB.
DR   GO; GO:0097493; F:structural molecule activity conferring elasticity; TAS:BHF-UCL.
DR   GO; GO:0031433; F:telethonin binding; IPI:BHF-UCL.
DR   GO; GO:0007512; P:adult heart development; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0048739; P:cardiac muscle fiber development; IMP:BHF-UCL.
DR   GO; GO:0003300; P:cardiac muscle hypertrophy; IMP:BHF-UCL.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0055003; P:cardiac myofibril assembly; IMP:BHF-UCL.
DR   GO; GO:0035995; P:detection of muscle stretch; TAS:BHF-UCL.
DR   GO; GO:0043056; P:forward locomotion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007076; P:mitotic chromosome condensation; IEP:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; NAS:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; IMP:BHF-UCL.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IMP:BHF-UCL.
DR   GO; GO:0048769; P:sarcomerogenesis; IMP:BHF-UCL.
DR   GO; GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:BHF-UCL.
DR   GO; GO:0030240; P:skeletal muscle thin filament assembly; IMP:BHF-UCL.
DR   GO; GO:0006941; P:striated muscle contraction; TAS:UniProtKB.
//
ID   TJAP1_HUMAN             Reviewed;         557 AA.
AC   Q5JTD0; Q05BH9; Q5JTD1; Q5JWW1; Q68DB2; Q6P2P3; Q9H7V7;
DE   RecName: Full=Tight junction-associated protein 1;
DE   AltName: Full=Protein incorporated later into tight junctions;
DE   AltName: Full=Tight junction protein 4;
GN   Name=TJAP1; Synonyms=PILT, TJP4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   TKN1_HUMAN              Reviewed;         129 AA.
AC   P20366; O60600; O60601; Q00072; Q53GH4; Q549V0; Q549V1; Q549V2;
AC   Q6FHM1;
DE   RecName: Full=Protachykinin-1;
DE   AltName: Full=PPT;
DE   Contains:
DE     RecName: Full=Substance P;
DE   Contains:
DE     RecName: Full=Neurokinin A;
DE              Short=NKA;
DE     AltName: Full=Neuromedin L;
DE     AltName: Full=Substance K;
DE   Contains:
DE     RecName: Full=Neuropeptide K;
DE              Short=NPK;
DE   Contains:
DE     RecName: Full=Neuropeptide gamma;
DE   Contains:
DE     RecName: Full=C-terminal-flanking peptide;
DE   Flags: Precursor;
GN   Name=TAC1; Synonyms=NKA, NKNA, TAC2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0009582; P:detection of abiotic stimulus; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0007320; P:insemination; TAS:ProtInc.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0010459; P:negative regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0045760; P:positive regulation of action potential; IEA:Ensembl.
DR   GO; GO:0002675; P:positive regulation of acute inflammatory response; IEA:Ensembl.
DR   GO; GO:2000854; P:positive regulation of corticosterone secretion; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IEA:Ensembl.
DR   GO; GO:0050671; P:positive regulation of lymphocyte proliferation; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0046878; P:positive regulation of saliva secretion; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0043278; P:response to morphine; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:UniProtKB-KW.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; IEA:InterPro.
//
ID   TKN4_HUMAN              Reviewed;         113 AA.
AC   Q86UU9; Q2M2P1; Q6ECK8; Q86UU6; Q86UU7; Q86UU8; Q8IWZ7;
DE   RecName: Full=Tachykinin-4;
DE   AltName: Full=Preprotachykinin-C;
DE            Short=PPT-C;
DE   Contains:
DE     RecName: Full=Endokinin-A;
DE              Short=EKA;
DE   Contains:
DE     RecName: Full=Endokinin-A/B;
DE              Short=EKA/B;
DE   Contains:
DE     RecName: Full=Endokinin-C;
DE              Short=EKC;
DE   Flags: Precursor;
GN   Name=TAC4;
DR   GO; GO:0046878; P:positive regulation of saliva secretion; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:UniProtKB-KW.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; IEA:Ensembl.
//
ID   TKNK_HUMAN              Reviewed;         121 AA.
AC   Q9UHF0; Q6IAG2; Q71BC6; Q71BC9;
DE   RecName: Full=Tachykinin-3;
DE   AltName: Full=ZNEUROK1;
DE   Contains:
DE     RecName: Full=Neurokinin-B;
DE              Short=NKB;
DE     AltName: Full=Neuromedin-K;
DE   Flags: Precursor;
GN   Name=TAC3; Synonyms=NKNB; ORFNames=UNQ585/PRO1155;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0007217; P:tachykinin receptor signaling pathway; TAS:ProtInc.
//
ID   TKTL1_HUMAN             Reviewed;         596 AA.
AC   P51854; A8K896; Q5TYJ9; Q8TC75;
DE   RecName: Full=Transketolase-like protein 1;
DE            EC=2.2.1.1;
DE   AltName: Full=Transketolase 2;
DE            Short=TK 2;
DE   AltName: Full=Transketolase-related protein;
GN   Name=TKTL1; Synonyms=TKR, TKT2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004802; F:transketolase activity; TAS:ProtInc.
DR   GO; GO:0006007; P:glucose catabolic process; TAS:ProtInc.
DR   GO; GO:0006772; P:thiamine metabolic process; TAS:ProtInc.
//
ID   TKTL2_HUMAN             Reviewed;         626 AA.
AC   Q9H0I9; A4FVB4; Q8NCT0; Q96M82;
DE   RecName: Full=Transketolase-like protein 2;
DE            EC=2.2.1.1;
GN   Name=TKTL2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004802; F:transketolase activity; IEA:UniProtKB-EC.
//
ID   TKT_HUMAN               Reviewed;         623 AA.
AC   P29401; A8K089; B4DE31; E7EPA7; Q8TBA3; Q96HH3;
DE   RecName: Full=Transketolase;
DE            Short=TK;
DE            EC=2.2.1.1;
GN   Name=TKT;
DR   GO; GO:0048037; F:cofactor binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004802; F:transketolase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0046166; P:glyceraldehyde-3-phosphate biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006098; P:pentose-phosphate shunt; TAS:Reactome.
DR   GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; NAS:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0005999; P:xylulose biosynthetic process; TAS:Reactome.
//
ID   TLCD1_HUMAN             Reviewed;         247 AA.
AC   Q96CP7;
DE   RecName: Full=Calfacilitin;
DE   AltName: Full=TLC domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=TLCD1;
//
ID   TLCD2_HUMAN             Reviewed;         264 AA.
AC   A6NGC4;
DE   RecName: Full=TLC domain-containing protein 2;
GN   Name=TLCD2;
//
ID   TLDC1_HUMAN             Reviewed;         456 AA.
AC   Q6P9B6; Q8IZ64; Q9HCG3; Q9NTE8;
DE   RecName: Full=TLD domain-containing protein 1;
DE   AltName: Full=TBC/LysM-associated domain-containing protein 1;
GN   Name=TLDC1; Synonyms=KIAA1609;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TLDC2_HUMAN             Reviewed;         215 AA.
AC   A0PJX2; B3KVU8;
DE   RecName: Full=TLD domain-containing protein 2;
DE   AltName: Full=TBC/LysM-associated domain-containing protein 2;
GN   Name=TLDC2;
//
ID   TLE1_HUMAN              Reviewed;         770 AA.
AC   Q04724; A8K495; Q5T3G4; Q969V9;
DE   RecName: Full=Transducin-like enhancer protein 1;
DE   AltName: Full=E(Sp1) homolog;
DE   AltName: Full=Enhancer of split groucho-like protein 1;
DE            Short=ESG1;
GN   Name=TLE1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:2000811; P:negative regulation of anoikis; IMP:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; NAS:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TLE2_HUMAN              Reviewed;         743 AA.
AC   Q04725; B4DE03; E9PEV7; F8WCH2; Q8WVY0; Q9Y6S0;
DE   RecName: Full=Transducin-like enhancer protein 2;
DE   AltName: Full=Enhancer of split groucho-like protein 2;
DE            Short=ESG2;
GN   Name=TLE2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TLE3_HUMAN              Reviewed;         772 AA.
AC   Q04726; E9PD64; Q6PI57; Q8IVV6; Q8WVR2; Q9HCM5;
DE   RecName: Full=Transducin-like enhancer protein 3;
DE   AltName: Full=Enhancer of split groucho-like protein 3;
DE            Short=ESG3;
GN   Name=TLE3; Synonyms=KIAA1547;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TLE4_HUMAN              Reviewed;         773 AA.
AC   Q04727; Q3ZCS1; Q5T1Y2; Q6PCB3; Q9BZ07; Q9BZ08; Q9BZ09; Q9NSL3;
AC   Q9ULF9;
DE   RecName: Full=Transducin-like enhancer protein 4;
GN   Name=TLE4; Synonyms=KIAA1261;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TLE6_HUMAN              Reviewed;         572 AA.
AC   Q9H808; J3KMZ1;
DE   RecName: Full=Transducin-like enhancer protein 6;
GN   Name=TLE6;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   TLK1_HUMAN              Reviewed;         766 AA.
AC   Q9UKI8; B3KR15; B4DX87; Q14150; Q8N591; Q9NYH2; Q9Y4F6;
DE   RecName: Full=Serine/threonine-protein kinase tousled-like 1;
DE            EC=2.7.11.1;
DE   AltName: Full=PKU-beta;
DE   AltName: Full=Tousled-like kinase 1;
GN   Name=TLK1; Synonyms=KIAA0137;
DR   GuidetoPHARMACOLOGY; 2242; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001672; P:regulation of chromatin assembly or disassembly; IDA:UniProtKB.
//
ID   TLK2_HUMAN              Reviewed;         772 AA.
AC   Q86UE8; D3DU07; Q9UKI7; Q9Y4F7;
DE   RecName: Full=Serine/threonine-protein kinase tousled-like 2;
DE            EC=2.7.11.1;
DE   AltName: Full=HsHPK;
DE   AltName: Full=PKU-alpha;
DE   AltName: Full=Tousled-like kinase 2;
GN   Name=TLK2;
DR   GuidetoPHARMACOLOGY; 2243; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; NAS:BHF-UCL.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0001672; P:regulation of chromatin assembly or disassembly; IDA:UniProtKB.
//
ID   TLL1_HUMAN              Reviewed;        1013 AA.
AC   O43897; B2RMU2; Q96AN3; Q9NQS4;
DE   RecName: Full=Tolloid-like protein 1;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=TLL1; Synonyms=TLL;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   TLL2_HUMAN              Reviewed;        1015 AA.
AC   Q9Y6L7; A6NDK0; Q2M1H1; Q6PJN5; Q9UQ00;
DE   RecName: Full=Tolloid-like protein 2;
DE            EC=3.4.24.-;
DE   Flags: Precursor;
GN   Name=TLL2; Synonyms=KIAA0932;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   TLN1_HUMAN              Reviewed;        2541 AA.
AC   Q9Y490; A6NMY0; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3;
DE   RecName: Full=Talin-1;
GN   Name=TLN1; Synonyms=KIAA1027, TLN;
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0030274; F:LIM domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:UniProtKB.
DR   GO; GO:0007044; P:cell-substrate junction assembly; IEA:Ensembl.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; NAS:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
//
ID   TLN2_HUMAN              Reviewed;        2542 AA.
AC   Q9Y4G6; A6NLB8;
DE   RecName: Full=Talin-2;
GN   Name=TLN2; Synonyms=KIAA0320;
DR   GO; GO:0003779; F:actin binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:UniProtKB.
DR   GO; GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
//
ID   TLR10_HUMAN             Reviewed;         811 AA.
AC   Q9BXR5; A8K7L1; B3Y668; D1CS21; D1CS22; Q32MI7; Q32MI8; Q5FWG4;
AC   Q6UXL3;
DE   RecName: Full=Toll-like receptor 10;
DE   AltName: CD_antigen=CD290;
DE   Flags: Precursor;
GN   Name=TLR10; ORFNames=UNQ315/PRO358;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEA:InterPro.
DR   GO; GO:0050707; P:regulation of cytokine secretion; IEA:InterPro.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLR1_HUMAN              Reviewed;         786 AA.
AC   Q15399; D1CS39; D1CS41; O15452; Q32MK3; Q32MK4; Q9UG90;
DE   RecName: Full=Toll-like receptor 1;
DE   AltName: Full=Toll/interleukin-1 receptor-like protein;
DE            Short=TIL;
DE   AltName: CD_antigen=CD281;
DE   Flags: Precursor;
GN   Name=TLR1; Synonyms=KIAA0012;
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0071727; P:cellular response to triacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0042495; P:detection of triacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0042116; P:macrophage activation; NAS:UniProtKB.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
//
ID   TLR2_HUMAN              Reviewed;         784 AA.
AC   O60603; B3Y612; D1CS45; D1CS48; D1CS49; O15454; Q8NI00;
DE   RecName: Full=Toll-like receptor 2;
DE   AltName: Full=Toll/interleukin-1 receptor-like protein 4;
DE   AltName: CD_antigen=CD282;
DE   Flags: Precursor;
GN   Name=TLR2; Synonyms=TIL4;
DR   GuidetoPHARMACOLOGY; 1752; -.
DR   GO; GO:0042498; F:diacyl lipopeptide binding; IEA:Ensembl.
DR   GO; GO:0001875; F:lipopolysaccharide receptor activity; TAS:UniProtKB.
DR   GO; GO:0070891; F:lipoteichoic acid binding; IEA:Ensembl.
DR   GO; GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0008329; F:signaling pattern recognition receptor activity; IDA:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0042497; F:triacyl lipopeptide binding; IDA:MGI.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0002752; P:cell surface pattern recognition receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0071221; P:cellular response to bacterial lipopeptide; TAS:BHF-UCL.
DR   GO; GO:0071726; P:cellular response to diacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; IDA:MGI.
DR   GO; GO:0071224; P:cellular response to peptidoglycan; IEA:Ensembl.
DR   GO; GO:0071727; P:cellular response to triacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0032289; P:central nervous system myelin formation; IEA:Ensembl.
DR   GO; GO:0042892; P:chloramphenicol transport; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:UniProtKB.
DR   GO; GO:0042496; P:detection of diacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0042495; P:detection of triacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0052063; P:induction by symbiont of defense-related host nitric oxide production; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0006691; P:leukotriene metabolic process; IEA:Ensembl.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; IEA:Ensembl.
DR   GO; GO:0046209; P:nitric oxide metabolic process; IEA:Ensembl.
DR   GO; GO:0052033; P:pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032741; P:positive regulation of interleukin-18 production; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; IEA:Ensembl.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0002238; P:response to molecule of fungal origin; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:UniProtKB.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   TLR3_HUMAN              Reviewed;         904 AA.
AC   O15455; B2RAI7; B7Z7K0; E6Y0F0; E6Y0F1; E9PGH4; Q4VAL2; Q504W0;
DE   RecName: Full=Toll-like receptor 3;
DE   AltName: CD_antigen=CD283;
DE   Flags: Precursor;
GN   Name=TLR3;
DR   GuidetoPHARMACOLOGY; 1753; -.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; NAS:UniProtKB.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IEA:Ensembl.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:ProtInc.
DR   GO; GO:0051607; P:defense response to virus; TAS:BHF-UCL.
DR   GO; GO:0009597; P:detection of virus; NAS:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006972; P:hyperosmotic response; NAS:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0097527; P:necroptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.
DR   GO; GO:0052033; P:pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0034346; P:positive regulation of type III interferon production; IEA:Ensembl.
DR   GO; GO:0043330; P:response to exogenous dsRNA; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLR4_HUMAN              Reviewed;         839 AA.
AC   O00206; A8K1Y8; A9XLP9; A9XLQ0; A9XLQ1; B4E194; D1CS52; D1CS53;
AC   Q5VZI8; Q5VZI9; Q9UK78; Q9UM57;
DE   RecName: Full=Toll-like receptor 4;
DE   AltName: Full=hToll;
DE   AltName: CD_antigen=CD284;
DE   Flags: Precursor;
GN   Name=TLR4;
DR   GuidetoPHARMACOLOGY; 1754; -.
DR   GO; GO:0001530; F:lipopolysaccharide binding; NAS:UniProtKB.
DR   GO; GO:0001875; F:lipopolysaccharide receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; ISS:BHF-UCL.
DR   GO; GO:0002322; P:B cell proliferation involved in immune response; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0071223; P:cellular response to lipoteichoic acid; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IC:BHF-UCL.
DR   GO; GO:0016046; P:detection of fungus; NAS:UniProtKB.
DR   GO; GO:0032497; P:detection of lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0060729; P:intestinal epithelial structure maintenance; ISS:BHF-UCL.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IGI:MGI.
DR   GO; GO:0042116; P:macrophage activation; IMP:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:BHF-UCL.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; ISS:BHF-UCL.
DR   GO; GO:0032707; P:negative regulation of interleukin-23 production; ISS:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; NAS:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0002537; P:nitric oxide production involved in inflammatory response; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; ISS:BHF-UCL.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0032732; P:positive regulation of interleukin-1 production; ISS:BHF-UCL.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; IEA:Ensembl.
DR   GO; GO:0045348; P:positive regulation of MHC class II biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:MGI.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0070430; P:positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway; IEA:Ensembl.
DR   GO; GO:0070434; P:positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway; IEA:Ensembl.
DR   GO; GO:0010572; P:positive regulation of platelet activation; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IC:BHF-UCL.
DR   GO; GO:0042088; P:T-helper 1 type immune response; NAS:UniProtKB.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLR5_HUMAN              Reviewed;         858 AA.
AC   O60602; B1AZ05; B3Y633; B9VJ63; D1CS80; D3DTB8; O15456; Q32MI2;
AC   Q32MI3;
DE   RecName: Full=Toll-like receptor 5;
DE   AltName: Full=Toll/interleukin-1 receptor-like protein 3;
DE   Flags: Precursor;
GN   Name=TLR5; Synonyms=TIL3;
DR   GuidetoPHARMACOLOGY; 1755; -.
DR   GO; GO:0005149; F:interleukin-1 receptor binding; IPI:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLR6_HUMAN              Reviewed;         796 AA.
AC   Q9Y2C9; B3Y640; B6CH35; B6RFS4; B6RFS5;
DE   RecName: Full=Toll-like receptor 6;
DE   AltName: CD_antigen=CD286;
DE   Flags: Precursor;
GN   Name=TLR6;
DR   GO; GO:0042498; F:diacyl lipopeptide binding; IEA:Ensembl.
DR   GO; GO:0071723; F:lipopeptide binding; ISS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; NAS:UniProtKB.
DR   GO; GO:0071726; P:cellular response to diacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0042742; P:defense response to bacterium; TAS:ProtInc.
DR   GO; GO:0042496; P:detection of diacyl bacterial lipopeptide; IDA:MGI.
DR   GO; GO:0042495; P:detection of triacyl bacterial lipopeptide; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0046209; P:nitric oxide metabolic process; IEA:Ensembl.
DR   GO; GO:0052033; P:pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:MGI.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:MGI.
DR   GO; GO:0050707; P:regulation of cytokine secretion; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042088; P:T-helper 1 type immune response; IC:UniProtKB.
DR   GO; GO:0034130; P:toll-like receptor 1 signaling pathway; IEA:InterPro.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   TLR7_HUMAN              Reviewed;        1049 AA.
AC   Q9NYK1; D1CS69; Q9NR98;
DE   RecName: Full=Toll-like receptor 7;
DE   Flags: Precursor;
GN   Name=TLR7; ORFNames=UNQ248/PRO285;
DR   GuidetoPHARMACOLOGY; 1757; -.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.
DR   GO; GO:0035197; F:siRNA binding; ISS:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0052033; P:pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; IEA:Ensembl.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0034154; P:toll-like receptor 7 signaling pathway; IEA:Ensembl.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLR8_HUMAN              Reviewed;        1041 AA.
AC   Q9NR97; B3Y654; D1CS70; D1CS76; Q495P4; Q6UXL6; Q9NYG9;
DE   RecName: Full=Toll-like receptor 8;
DE   AltName: CD_antigen=CD288;
DE   Flags: Precursor;
GN   Name=TLR8; ORFNames=UNQ249/PRO286;
DR   GuidetoPHARMACOLOGY; 1758; -.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IMP:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; TAS:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0002282; P:microglial cell activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0052033; P:pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response; IEA:Ensembl.
DR   GO; GO:0045089; P:positive regulation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLR9_HUMAN              Reviewed;        1032 AA.
AC   Q9NR96; B3Y661; D1CS56; Q6UVZ2; Q9HD68; Q9HD69; Q9HD70; Q9NYC2;
AC   Q9NYC3;
DE   RecName: Full=Toll-like receptor 9;
DE   AltName: CD_antigen=CD289;
DE   Flags: Precursor;
GN   Name=TLR9; ORFNames=UNQ5798/PRO19605;
DR   GO; GO:0005149; F:interleukin-1 receptor binding; IPI:UniProtKB.
DR   GO; GO:0035197; F:siRNA binding; IMP:UniProtKB.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0042742; P:defense response to bacterium; NAS:UniProtKB.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IMP:UniProt.
DR   GO; GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:BHF-UCL.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; ISS:BHF-UCL.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.
DR   GO; GO:0032717; P:negative regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.
DR   GO; GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032741; P:positive regulation of interleukin-18 production; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IC:BHF-UCL.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0050707; P:regulation of cytokine secretion; IEA:InterPro.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; TAS:BHF-UCL.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TLX1_HUMAN              Reviewed;         330 AA.
AC   P31314; A1L4G3; O75699; Q5VXP2; Q9HCA0; Q9UD59;
DE   RecName: Full=T-cell leukemia homeobox protein 1;
DE   AltName: Full=Homeobox protein Hox-11;
DE   AltName: Full=Proto-oncogene TCL-3;
DE   AltName: Full=T-cell leukemia/lymphoma protein 3;
GN   Name=TLX1; Synonyms=HOX11, TCL3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048645; P:organ formation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
//
ID   TLX3_HUMAN              Reviewed;         291 AA.
AC   O43711; Q96AD3;
DE   RecName: Full=T-cell leukemia homeobox protein 3;
DE   AltName: Full=Homeobox protein Hox-11L2;
GN   Name=TLX3; Synonyms=HOX11L2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Ensembl.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
//
ID   TLXNB_HUMAN             Reviewed;         122 AA.
AC   P0CAT3;
DE   RecName: Full=Putative TLX1 neighbor protein;
DE   AltName: Full=TLX1 divergent gene protein;
GN   Name=TLX1NB; Synonyms=TDI;
//
ID   TM100_HUMAN             Reviewed;         134 AA.
AC   Q9NV29; D3DTY7; I3L214; Q96FZ0;
DE   RecName: Full=Transmembrane protein 100;
GN   Name=TMEM100;
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0060842; P:arterial endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0045603; P:positive regulation of endothelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   TM101_HUMAN             Reviewed;         257 AA.
AC   Q96IK0; B2R9N6;
DE   RecName: Full=Transmembrane protein 101;
DE   AltName: Full=Putative NF-kappa-B-activating protein 130;
GN   Name=TMEM101;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TLX2_HUMAN              Reviewed;         284 AA.
AC   O43763; Q9UD56; Q9UQ48;
DE   RecName: Full=T-cell leukemia homeobox protein 2;
DE   AltName: Full=Homeobox protein Hox-11L1;
DE   AltName: Full=Neural crest homeobox protein;
GN   Name=TLX2; Synonyms=HOX11L1, NCX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0048484; P:enteric nervous system development; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0050774; P:negative regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TM102_HUMAN             Reviewed;         508 AA.
AC   Q8N9M5; D3DTP8;
DE   RecName: Full=Transmembrane protein 102;
DE   AltName: Full=Common beta-chain associated protein;
DE            Short=CBAP;
GN   Name=TMEM102;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:1901028; P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
//
ID   TM104_HUMAN             Reviewed;         496 AA.
AC   Q8NE00; Q8TEU1; Q9NT56; Q9NXH1;
DE   RecName: Full=Transmembrane protein 104;
GN   Name=TMEM104;
//
ID   TM107_HUMAN             Reviewed;         140 AA.
AC   Q6UX40; A0PJV7; Q6NSE3; Q6ZRX9; Q96T82;
DE   RecName: Full=Transmembrane protein 107;
GN   Name=TMEM107; ORFNames=DC20, UNQ638/PRO1268;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0021532; P:neural tube patterning; IEA:Ensembl.
//
ID   TM105_HUMAN             Reviewed;         129 AA.
AC   Q8N8V8;
DE   RecName: Full=Transmembrane protein 105;
GN   Name=TMEM105;
//
ID   TM108_HUMAN             Reviewed;         575 AA.
AC   Q6UXF1; D3DNC9; Q9BQH1; Q9BW81; Q9C0H3;
DE   RecName: Full=Transmembrane protein 108;
DE   Flags: Precursor;
GN   Name=TMEM108; Synonyms=KIAA1690; ORFNames=UNQ1875/PRO4318;
//
ID   TM109_HUMAN             Reviewed;         243 AA.
AC   Q9BVC6;
DE   RecName: Full=Transmembrane protein 109;
DE   AltName: Full=Mitsugumin-23;
DE            Short=Mg23;
DE   Flags: Precursor;
GN   Name=TMEM109;
DR   GO; GO:0071480; P:cellular response to gamma radiation; IMP:MGI.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:MGI.
//
ID   TM10A_HUMAN             Reviewed;         339 AA.
AC   Q8TBZ6; B2R8X7; Q9Y2T9;
DE   RecName: Full=tRNA methyltransferase 10 homolog A;
DE            EC=2.1.1.-;
DE   AltName: Full=RNA (guanine-9-)-methyltransferase domain-containing protein 2;
GN   Name=TRMT10A; Synonyms=RG9MTD2;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   TM10B_HUMAN             Reviewed;         316 AA.
AC   Q6PF06; B7Z216; Q05DJ4; Q5QP83; Q8NAG2; Q96N36;
DE   RecName: Full=tRNA methyltransferase 10 homolog B;
DE            EC=2.1.1.-;
DE   AltName: Full=RNA (guanine-9-)-methyltransferase domain-containing protein 3;
GN   Name=TRMT10B; Synonyms=RG9MTD3;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
//
ID   TM110_HUMAN             Reviewed;         294 AA.
AC   Q86TL2;
DE   RecName: Full=Transmembrane protein 110;
GN   Name=TMEM110;
//
ID   TM114_HUMAN             Reviewed;         223 AA.
AC   B3SHH9;
DE   RecName: Full=Transmembrane protein 114;
GN   Name=TMEM114;
//
ID   TM115_HUMAN             Reviewed;         351 AA.
AC   Q12893; A2IDB7; O14568; Q6IAY4; Q9UIX3;
DE   RecName: Full=Transmembrane protein 115;
DE   AltName: Full=Placental protein 6;
DE            Short=PP6;
DE   AltName: Full=Protein PL6;
GN   Name=TMEM115; Synonyms=PL6; ORFNames=LUCA11.2;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
//
ID   TM116_HUMAN             Reviewed;         245 AA.
AC   Q8NCL8; G3V1W7; G5E985; Q6NSH5; Q8IZ66;
DE   RecName: Full=Transmembrane protein 116;
GN   Name=TMEM116;
//
ID   TM119_HUMAN             Reviewed;         283 AA.
AC   Q4V9L6; Q6UXE5; Q8N2F5;
DE   RecName: Full=Transmembrane protein 119;
DE   AltName: Full=Osteoblast induction factor;
DE            Short=OBIF;
DE   Flags: Precursor;
GN   Name=TMEM119; ORFNames=PSEC0199, UNQ731/PRO1415;
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
//
ID   TM117_HUMAN             Reviewed;         514 AA.
AC   Q9H0C3;
DE   RecName: Full=Transmembrane protein 117;
GN   Name=TMEM117;
//
ID   TM11B_HUMAN             Reviewed;         416 AA.
AC   Q86T26; A8K4D9;
DE   RecName: Full=Transmembrane protease serine 11B;
DE            EC=3.4.21.-;
DE   AltName: Full=Airway trypsin-like protease 5;
GN   Name=TMPRSS11B; Synonyms=HATL5;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   TM11A_HUMAN             Reviewed;         421 AA.
AC   Q6ZMR5; J3KNQ8; Q2NKI9; Q6JE90; Q7RTY4; Q86TK8;
DE   RecName: Full=Transmembrane protease serine 11A;
DE            EC=3.4.21.-;
DE   AltName: Full=Airway trypsin-like protease 1;
DE   AltName: Full=Epidermal type-II transmembrane serine protease;
DE   AltName: Full=Esophageal cancer-susceptibility gene 1 protein;
GN   Name=TMPRSS11A; Synonyms=ECRG1, HATL1, HESP;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   TM11D_HUMAN             Reviewed;         418 AA.
AC   O60235; Q08AF6;
DE   RecName: Full=Transmembrane protease serine 11D;
DE            EC=3.4.21.-;
DE   AltName: Full=Airway trypsin-like protease;
DE   Contains:
DE     RecName: Full=Transmembrane protease serine 11D non-catalytic chain;
DE   Contains:
DE     RecName: Full=Transmembrane protease serine 11D catalytic chain;
DE   Flags: Precursor;
GN   Name=TMPRSS11D; Synonyms=HAT;
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
//
ID   TM11F_HUMAN             Reviewed;         438 AA.
AC   Q6ZWK6; A8MXX2;
DE   RecName: Full=Transmembrane protease serine 11F;
DE            EC=3.4.21.-;
DE   AltName: Full=Airway trypsin-like protease 4;
GN   Name=TMPRSS11F; Synonyms=HATL4;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   TM11E_HUMAN             Reviewed;         423 AA.
AC   Q9UL52; A6NL71; Q14DC8; Q6UW31;
DE   RecName: Full=Transmembrane protease serine 11E;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease DESC1;
DE   AltName: Full=Transmembrane protease serine 11E2;
DE   Contains:
DE     RecName: Full=Transmembrane protease serine 11E non-catalytic chain;
DE   Contains:
DE     RecName: Full=Transmembrane protease serine 11E catalytic chain;
DE   Flags: Precursor;
GN   Name=TMPRSS11E; Synonyms=DESC1, TMPRSS11E2; ORFNames=UNQ742/PRO1461;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
//
ID   TM11L_HUMAN             Reviewed;         105 AA.
AC   B3KVV0;
DE   RecName: Full=Transmembrane protease serine 11B-like protein;
DE   AltName: Full=TMPRSS11B N-terminus-like protein;
GN   Name=TMPRSS11BNL;
//
ID   TM121_HUMAN             Reviewed;         319 AA.
AC   Q9BTD3;
DE   RecName: Full=Transmembrane protein 121;
GN   Name=TMEM121;
//
ID   TM125_HUMAN             Reviewed;         219 AA.
AC   Q96AQ2; D3DPX1;
DE   RecName: Full=Transmembrane protein 125;
GN   Name=TMEM125;
//
ID   TM127_HUMAN             Reviewed;         238 AA.
AC   O75204; D3DXH0;
DE   RecName: Full=Transmembrane protein 127;
GN   Name=TMEM127;
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
//
ID   TM128_HUMAN             Reviewed;         165 AA.
AC   Q5BJH2; B4DHS7; D3DVS3; Q5H9U6; Q96I94;
DE   RecName: Full=Transmembrane protein 128;
GN   Name=TMEM128;
//
ID   TM129_HUMAN             Reviewed;         362 AA.
AC   A0AVI4; A6NH49; A6NI98; D3DVP8;
DE   RecName: Full=Transmembrane protein 129;
DE   Flags: Precursor;
GN   Name=TMEM129;
//
ID   TM130_HUMAN             Reviewed;         435 AA.
AC   Q8N3G9; A4D266; B7Z364; Q8IY46; Q8N0W9; Q8N3R2;
DE   RecName: Full=Transmembrane protein 130;
DE   Flags: Precursor;
GN   Name=TMEM130; ORFNames=UNQ719/PRO1383;
//
ID   TM131_HUMAN             Reviewed;        1883 AA.
AC   Q92545;
DE   RecName: Full=Transmembrane protein 131;
DE   AltName: Full=Protein RW1;
GN   Name=TMEM131; Synonyms=KIAA0257, RW1;
//
ID   TM134_HUMAN             Reviewed;         195 AA.
AC   Q9H6X4; Q08AK4; Q6PJN3;
DE   RecName: Full=Transmembrane protein 134;
GN   Name=TMEM134;
//
ID   TM133_HUMAN             Reviewed;         129 AA.
AC   Q9H2Q1;
DE   RecName: Full=Transmembrane protein 133;
GN   Name=TMEM133; ORFNames=AD031;
//
ID   TM135_HUMAN             Reviewed;         458 AA.
AC   Q86UB9; Q6AW91; Q8ND01; Q9H6M3;
DE   RecName: Full=Transmembrane protein 135;
DE   AltName: Full=Peroxisomal membrane protein 52;
DE            Short=PMP52;
GN   Name=TMEM135;
DR   GO; GO:0007031; P:peroxisome organization; ISS:UniProtKB.
//
ID   TM138_HUMAN             Reviewed;         162 AA.
AC   Q9NPI0; A6NGA7; B4E044; Q5JPE1;
DE   RecName: Full=Transmembrane protein 138;
GN   Name=TMEM138; ORFNames=HSPC196, HSPC198;
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
//
ID   TM136_HUMAN             Reviewed;         245 AA.
AC   Q6ZRR5; B4DGQ4; B4E230; Q8IZ79;
DE   RecName: Full=Transmembrane protein 136;
GN   Name=TMEM136;
//
ID   TM140_HUMAN             Reviewed;         185 AA.
AC   Q9NV12; A4D1P9; Q8WUC3;
DE   RecName: Full=Transmembrane protein 140;
GN   Name=TMEM140;
//
ID   TM139_HUMAN             Reviewed;         216 AA.
AC   Q8IV31; B2RCL5; D3DXD4; Q6ZME2; Q8NC22; Q96AU8;
DE   RecName: Full=Transmembrane protein 139;
DE   Flags: Precursor;
GN   Name=TMEM139; ORFNames=UNQ1932/PRO4407;
//
ID   TM143_HUMAN             Reviewed;         459 AA.
AC   Q96AN5; A8K656; Q6UXY4; Q9NV49;
DE   RecName: Full=Transmembrane protein 143;
GN   Name=TMEM143; ORFNames=UNQ5922/PRO19813;
//
ID   TM141_HUMAN             Reviewed;         108 AA.
AC   Q96I45; A6NIZ7; Q5T5R5;
DE   RecName: Full=Transmembrane protein 141;
GN   Name=TMEM141;
//
ID   TM144_HUMAN             Reviewed;         345 AA.
AC   Q7Z5S9; D3DP24; Q49A05; Q9NUT3;
DE   RecName: Full=Transmembrane protein 144;
GN   Name=TMEM144;
//
ID   TM145_HUMAN             Reviewed;         493 AA.
AC   Q8NBT3;
DE   RecName: Full=Transmembrane protein 145;
GN   Name=TMEM145;
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
//
ID   TM147_HUMAN             Reviewed;         224 AA.
AC   Q9BVK8; A8MWW0; O75790;
DE   RecName: Full=Transmembrane protein 147;
DE   AltName: Full=Protein NIFIE 14;
GN   Name=TMEM147;
//
ID   TM148_HUMAN             Reviewed;         119 AA.
AC   Q8N616;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00311;
GN   Name=LINC00311; Synonyms=NCRNA00311, TMEM148;
//
ID   TM14A_HUMAN             Reviewed;          99 AA.
AC   Q9Y6G1; B2R552;
DE   RecName: Full=Transmembrane protein 14A;
GN   Name=TMEM14A; Synonyms=C6orf73; ORFNames=PTD011;
//
ID   TM14B_HUMAN             Reviewed;         114 AA.
AC   Q9NUH8; Q5THN7; Q5THN8; Q96IX7; Q9BVN8;
DE   RecName: Full=Transmembrane protein 14B;
GN   Name=TMEM14B;
//
ID   TM14C_HUMAN             Reviewed;         112 AA.
AC   Q9P0S9; Q5T4I6;
DE   RecName: Full=Transmembrane protein 14C;
GN   Name=TMEM14C; Synonyms=C6orf53; ORFNames=HSPC194;
DR   GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
//
ID   TM14D_HUMAN             Reviewed;         114 AA.
AC   A8MWL7;
DE   RecName: Full=Transmembrane protein 14D;
GN   Name=TMEM14D;
//
ID   TM14E_HUMAN             Reviewed;         125 AA.
AC   Q6UXP3;
DE   RecName: Full=Transmembrane protein 14E;
GN   Name=TMEM14E; ORFNames=UNQ9344/PRO34067;
//
ID   TM154_HUMAN             Reviewed;         183 AA.
AC   Q6P9G4; Q8WUT7; Q96MQ8;
DE   RecName: Full=Transmembrane protein 154;
DE   Flags: Precursor;
GN   Name=TMEM154;
//
ID   TM156_HUMAN             Reviewed;         296 AA.
AC   Q8N614; Q9H5N9;
DE   RecName: Full=Transmembrane protein 156;
GN   Name=TMEM156;
//
ID   TM155_HUMAN             Reviewed;         130 AA.
AC   Q4W5P6; D3DNW9; Q96NI2;
DE   RecName: Full=Protein TMEM155;
DE   Flags: Precursor;
GN   Name=TMEM155;
//
ID   TM158_HUMAN             Reviewed;         300 AA.
AC   Q8WZ71; Q6PFW5; Q9Y4M1;
DE   RecName: Full=Transmembrane protein 158;
DE   AltName: Full=40 kDa BINP-binding protein;
DE            Short=p40BBP;
DE   AltName: Full=Ras-induced senescence protein 1;
DE   Flags: Precursor;
GN   Name=TMEM158; Synonyms=HBBP, RIS1;
DR   GO; GO:0042277; F:peptide binding; IEA:Ensembl.
//
ID   TM159_HUMAN             Reviewed;         161 AA.
AC   Q96B96; A6NMA9; O00323;
DE   RecName: Full=Promethin;
DE   AltName: Full=Transmembrane protein 159;
GN   Name=TMEM159;
//
ID   TM160_HUMAN             Reviewed;         188 AA.
AC   Q9NX00; Q9BU41;
DE   RecName: Full=Transmembrane protein 160;
GN   Name=TMEM160;
//
ID   TM163_HUMAN             Reviewed;         289 AA.
AC   Q8TC26; Q53QM3; Q53SV7; Q69YH3; Q9UFG3;
DE   RecName: Full=Transmembrane protein 163;
GN   Name=TMEM163;
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
//
ID   TM164_HUMAN             Reviewed;         297 AA.
AC   Q5U3C3; B3KSQ8; F5H2P2;
DE   RecName: Full=Transmembrane protein 164;
GN   Name=TMEM164;
//
ID   TM165_HUMAN             Reviewed;         324 AA.
AC   Q9HC07; A8K3P8; Q9BTN9; Q9NZ34;
DE   RecName: Full=Transmembrane protein 165;
DE   AltName: Full=Transmembrane protein PT27;
DE   AltName: Full=Transmembrane protein TPARL;
DE   Flags: Precursor;
GN   Name=TMEM165; Synonyms=TPARL;
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IGI:UniProtKB.
DR   GO; GO:0032472; P:Golgi calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IMP:UniProtKB.
DR   GO; GO:0035751; P:regulation of lysosomal lumen pH; IMP:UniProtKB.
//
ID   TM168_HUMAN             Reviewed;         697 AA.
AC   Q9H0V1; A4D0T9; Q8NEK4; Q9H8J2;
DE   RecName: Full=Transmembrane protein 168;
GN   Name=TMEM168;
//
ID   TM169_HUMAN             Reviewed;         297 AA.
AC   Q96HH4; B2R8W6;
DE   RecName: Full=Transmembrane protein 169;
GN   Name=TMEM169;
//
ID   TM171_HUMAN             Reviewed;         324 AA.
AC   Q8WVE6; Q8N0S1; Q8TDT7;
DE   RecName: Full=Transmembrane protein 171;
GN   Name=TMEM171;
//
ID   TM174_HUMAN             Reviewed;         243 AA.
AC   Q8WUU8; B2RDA0; Q96N81;
DE   RecName: Full=Transmembrane protein 174;
GN   Name=TMEM174;
//
ID   TM175_HUMAN             Reviewed;         504 AA.
AC   Q9BSA9; D3DVN4; Q8ND13;
DE   RecName: Full=Transmembrane protein 175;
GN   Name=TMEM175;
//
ID   TM177_HUMAN             Reviewed;         311 AA.
AC   Q53S58; Q9BT20;
DE   RecName: Full=Transmembrane protein 177;
GN   Name=TMEM177;
//
ID   TM180_HUMAN             Reviewed;         517 AA.
AC   Q14CX5; Q6NWM8; Q6NWM9; Q6PEZ7; Q9H679;
DE   RecName: Full=Transmembrane protein 180;
GN   Name=TMEM180; Synonyms=C10orf77;
//
ID   TM181_HUMAN             Reviewed;         612 AA.
AC   Q9P2C4; Q5VTU1;
DE   RecName: Full=Transmembrane protein 181;
GN   Name=TMEM181; Synonyms=GPR178, KIAA1423;
DR   GO; GO:0015643; F:toxic substance binding; IDA:UniProtKB.
DR   GO; GO:0009405; P:pathogenesis; IMP:UniProtKB.
//
ID   TM182_HUMAN             Reviewed;         229 AA.
AC   Q6ZP80; C9JML7; Q3B7B8; Q53TT9; Q6GMU0; Q8WW45; Q96NR4;
DE   RecName: Full=Transmembrane protein 182;
DE   Flags: Precursor;
GN   Name=TMEM182; ORFNames=UNQ6974/PRO21957;
//
ID   TM186_HUMAN             Reviewed;         213 AA.
AC   Q96B77; B2RAY0; Q9Y4T4;
DE   RecName: Full=Transmembrane protein 186;
GN   Name=TMEM186; Synonyms=C16orf51;
//
ID   TM187_HUMAN             Reviewed;         261 AA.
AC   Q14656; B2RC47; Q6IAV7;
DE   RecName: Full=Transmembrane protein 187;
DE   AltName: Full=Protein ITBA1;
GN   Name=TMEM187; Synonyms=CXorf12, DXS9878E, ITBA1;
//
ID   TM189_HUMAN             Reviewed;         270 AA.
AC   A5PLL7;
DE   RecName: Full=Transmembrane protein 189;
GN   Name=TMEM189; Synonyms=KUA;
//
ID   TM190_HUMAN             Reviewed;         177 AA.
AC   Q8WZ59; A6NJL5;
DE   RecName: Full=Transmembrane protein 190;
DE   Flags: Precursor;
GN   Name=TMEM190; Synonyms=MDAC1;
//
ID   TM192_HUMAN             Reviewed;         271 AA.
AC   Q8IY95; Q7Z3A1; Q8N928;
DE   RecName: Full=Transmembrane protein 192;
GN   Name=TMEM192;
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
//
ID   TM196_HUMAN             Reviewed;         178 AA.
AC   Q5HYL7; Q8N6I6;
DE   RecName: Full=Transmembrane protein 196;
GN   Name=TMEM196;
//
ID   TM199_HUMAN             Reviewed;         208 AA.
AC   Q8N511;
DE   RecName: Full=Transmembrane protein 199;
GN   Name=TMEM199; Synonyms=C17orf32;
//
ID   TM198_HUMAN             Reviewed;         360 AA.
AC   Q66K66;
DE   RecName: Full=Transmembrane protein 198;
GN   Name=TMEM198;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TM1L1_HUMAN             Reviewed;         476 AA.
AC   O75674; Q53G06;
DE   RecName: Full=TOM1-like protein 1;
DE   AltName: Full=Src-activating and signaling molecule protein;
DE   AltName: Full=Target of Myb-like protein 1;
GN   Name=TOM1L1; Synonyms=SRCASM;
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030295; F:protein kinase activator activity; IEA:Ensembl.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; TAS:HGNC.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0045839; P:negative regulation of mitosis; IDA:UniProtKB.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProtKB.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; NAS:HGNC.
//
ID   TM1L2_HUMAN             Reviewed;         507 AA.
AC   Q6ZVM7; B7Z7F4; Q86V61; Q8TDE7; Q96M88;
DE   RecName: Full=TOM1-like protein 2;
DE   AltName: Full=Target of Myb-like protein 2;
GN   Name=TOM1L2;
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0045839; P:negative regulation of mitosis; IDA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IDA:UniProt.
//
ID   TM201_HUMAN             Reviewed;         666 AA.
AC   Q5SNT2; B9EH90; Q5SNT3;
DE   RecName: Full=Transmembrane protein 201;
DE   AltName: Full=Spindle-associated membrane protein 1;
GN   Name=TMEM201; Synonyms=NET5, SAMP1;
//
ID   TM202_HUMAN             Reviewed;         273 AA.
AC   A6NGA9;
DE   RecName: Full=Transmembrane protein 202;
GN   Name=TMEM202;
//
ID   TM203_HUMAN             Reviewed;         136 AA.
AC   Q969S6; Q6NW08;
DE   RecName: Full=Transmembrane protein 203;
GN   Name=TMEM203;
//
ID   TM204_HUMAN             Reviewed;         226 AA.
AC   Q9BSN7; D3DU76; Q3KRC1; Q9H7G5;
DE   RecName: Full=Transmembrane protein 204;
DE   AltName: Full=Claudin-like protein 24;
GN   Name=TMEM204; Synonyms=C16orf30, CLP24; ORFNames=UNQ6509/PRO21434;
DR   GO; GO:0001945; P:lymph vessel development; IEA:Ensembl.
DR   GO; GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; IEA:UniProtKB-KW.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
//
ID   TM205_HUMAN             Reviewed;         189 AA.
AC   Q6UW68;
DE   RecName: Full=Transmembrane protein 205;
GN   Name=TMEM205; ORFNames=UNQ501/PRO1018;
//
ID   TM206_HUMAN             Reviewed;         350 AA.
AC   Q9H813; B7Z4D6; Q6IA87; Q9NV85;
DE   RecName: Full=Transmembrane protein 206;
GN   Name=TMEM206; Synonyms=C1orf75;
//
ID   TM207_HUMAN             Reviewed;         146 AA.
AC   Q6UWW9;
DE   RecName: Full=Transmembrane protein 207;
DE   Flags: Precursor;
GN   Name=TMEM207; ORFNames=UNQ846/PRO1784;
//
ID   TM208_HUMAN             Reviewed;         173 AA.
AC   Q9BTX3; Q05CT0; Q96D25; Q9NZZ7;
DE   RecName: Full=Transmembrane protein 208;
GN   Name=TMEM208; ORFNames=HSPC171;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   TM210_HUMAN             Reviewed;         147 AA.
AC   A6NLX4;
DE   RecName: Full=Transmembrane protein 210;
DE   Flags: Precursor;
GN   Name=TMEM210;
//
ID   TM209_HUMAN             Reviewed;         561 AA.
AC   Q96SK2; A4D1L1; Q49A50; Q6PF00; Q8NCH3; Q96SL6;
DE   RecName: Full=Transmembrane protein 209;
GN   Name=TMEM209;
//
ID   TM211_HUMAN             Reviewed;         200 AA.
AC   Q6ICI0;
DE   RecName: Full=Transmembrane protein 211;
GN   Name=TMEM211;
//
ID   TM212_HUMAN             Reviewed;         194 AA.
AC   A6NML5;
DE   RecName: Full=Transmembrane protein 212;
GN   Name=TMEM212;
//
ID   TM213_HUMAN             Reviewed;         107 AA.
AC   A2RRL7; A4D1R3; C9JH49; C9JX41; C9K0P0;
DE   RecName: Full=Transmembrane protein 213;
DE   Flags: Precursor;
GN   Name=TMEM213;
//
ID   TM214_HUMAN             Reviewed;         689 AA.
AC   Q6NUQ4; A6NNF2; B3KUI9; B5MCD8; D6W547; Q53SW1; Q69YH4; Q8NC45;
AC   Q8WZ37; Q9NXH2;
DE   RecName: Full=Transmembrane protein 214;
GN   Name=TMEM214; ORFNames=PP446;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   TM216_HUMAN             Reviewed;         145 AA.
AC   Q9P0N5; A8MZ23; B7Z8N1;
DE   RecName: Full=Transmembrane protein 216;
GN   Name=TMEM216; ORFNames=HSPC244;
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
//
ID   TM215_HUMAN             Reviewed;         235 AA.
AC   Q68D42; Q6ZUU2;
DE   RecName: Full=Transmembrane protein 215;
GN   Name=TMEM215;
//
ID   TM217_HUMAN             Reviewed;         229 AA.
AC   Q8N7C4; Q8TC54;
DE   RecName: Full=Transmembrane protein 217;
GN   Name=TMEM217; Synonyms=C6orf128;
//
ID   TM218_HUMAN             Reviewed;         115 AA.
AC   A2RU14; B7ZM48;
DE   RecName: Full=Transmembrane protein 218;
GN   Name=TMEM218;
//
ID   TM219_HUMAN             Reviewed;         240 AA.
AC   Q86XT9; D5FK14; Q8WVV8;
DE   RecName: Full=Insulin-like growth factor-binding protein 3 receptor;
DE            Short=IGFBP-3R;
DE   AltName: Full=Transmembrane protein 219;
DE   Flags: Precursor;
GN   Name=TMEM219;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   TM220_HUMAN             Reviewed;         160 AA.
AC   Q6QAJ8; A1YRJ4; B2RNE4; B4DJ52; B9EGW3;
DE   RecName: Full=Transmembrane protein 220;
GN   Name=TMEM220;
//
ID   TM221_HUMAN             Reviewed;         291 AA.
AC   A6NGB7;
DE   RecName: Full=Transmembrane protein 221;
GN   Name=TMEM221;
//
ID   TM222_HUMAN             Reviewed;         208 AA.
AC   Q9H0R3; D3DPL6; Q53HD8; Q5FVE9;
DE   RecName: Full=Transmembrane protein 222;
GN   Name=TMEM222; Synonyms=C1orf160;
//
ID   TM223_HUMAN             Reviewed;         202 AA.
AC   A0PJW6; Q504S0; Q86YD4; Q8WUC5; Q96HG0;
DE   RecName: Full=Transmembrane protein 223;
GN   Name=TMEM223;
//
ID   TM225_HUMAN             Reviewed;         225 AA.
AC   Q6GV28;
DE   RecName: Full=Transmembrane protein 225;
GN   Name=TMEM225; Synonyms=PMP22CD;
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   TM230_HUMAN             Reviewed;         120 AA.
AC   Q96A57; B2RDM8; D3DVZ9; Q0VGC8; Q5TDS5; Q96ES2; Q9P0A7;
DE   RecName: Full=Transmembrane protein 230;
GN   Name=TMEM230; Synonyms=C20orf30; ORFNames=HSPC274, UNQ2432/PRO4992;
//
ID   TM231_HUMAN             Reviewed;         316 AA.
AC   Q9H6L2; A0JLU1; A6NDZ6; B3KU85; G5E9E3; Q6P450; Q6UWW5;
DE   RecName: Full=Transmembrane protein 231;
GN   Name=TMEM231; ORFNames=UNQ870/PRO1886;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   TM232_HUMAN             Reviewed;         657 AA.
AC   C9JQI7; B4DKF4;
DE   RecName: Full=Transmembrane protein 232;
GN   Name=TMEM232;
//
ID   TM234_HUMAN             Reviewed;         164 AA.
AC   Q8WY98; B2R535; D3DPP7; Q6UWY9; Q8N2H6; Q9BSR2; Q9NU76;
DE   RecName: Full=Transmembrane protein 234;
GN   Name=TMEM234; Synonyms=C1orf91; ORFNames=PP1065, UNQ548/PRO1105;
//
ID   TM233_HUMAN             Reviewed;         109 AA.
AC   B4DJY2;
DE   RecName: Full=Transmembrane protein 233;
DE   AltName: Full=Dispanin subfamily B member 2;
DE            Short=DSPB2;
DE   AltName: Full=Interferon-induced transmembrane domain-containing protein D2;
GN   Name=TMEM233; Synonyms=IFITMD2;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   TM235_HUMAN             Reviewed;         223 AA.
AC   A6NFC5; C9JRE6;
DE   RecName: Full=Transmembrane protein 235;
DE   Flags: Precursor;
GN   Name=TMEM235;
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
//
ID   TM236_HUMAN             Reviewed;         351 AA.
AC   Q5W0B7; B2RXH7;
DE   RecName: Full=Transmembrane protein 236;
GN   Name=TMEM236; Synonyms=FAM23A, FAM23B;
//
ID   TM237_HUMAN             Reviewed;         408 AA.
AC   Q96Q45; B4E1R8; B4E2R8; E9PAR8; E9PBF8; E9PG24; E9PGX0; Q53TS9;
AC   Q53TT2; Q7Z3B6; Q8IZ18; Q8NBF8; Q96CY1;
DE   RecName: Full=Transmembrane protein 237;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein;
GN   Name=TMEM237; Synonyms=ALS2CR4;
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0030111; P:regulation of Wnt signaling pathway; IMP:UniProtKB.
//
ID   TM238_HUMAN             Reviewed;         176 AA.
AC   C9JI98;
DE   RecName: Full=Transmembrane protein 238;
GN   Name=TMEM238;
//
ID   TM239_HUMAN             Reviewed;         195 AA.
AC   Q8WW34; Q5JY54; Q6ZU23;
DE   RecName: Full=Transmembrane protein 239;
GN   Name=TMEM239;
//
ID   TM240_HUMAN             Reviewed;         173 AA.
AC   Q5SV17; B9EJG7;
DE   RecName: Full=Transmembrane protein 240;
GN   Name=TMEM240; Synonyms=C1orf70;
//
ID   TM241_HUMAN             Reviewed;         296 AA.
AC   Q24JQ0; I0J130; Q6ZTS7; Q6ZW41;
DE   RecName: Full=Transmembrane protein 241;
GN   Name=TMEM241; Synonyms=C18orf45;
//
ID   TM242_HUMAN             Reviewed;         141 AA.
AC   Q9NWH2; B9EJD0; Q9NZ88; Q9P094;
DE   RecName: Full=Transmembrane protein 242;
GN   Name=TMEM242; Synonyms=C6orf35; ORFNames=BM-033, HSPC287;
//
ID   TM243_HUMAN             Reviewed;         118 AA.
AC   Q9BU79; A4D1C6; B2R9I4; D6W5P1;
DE   RecName: Full=Transmembrane protein 243;
GN   Name=TMEM243; Synonyms=C7orf23;
//
ID   TM244_HUMAN             Reviewed;         128 AA.
AC   Q5VVB8;
DE   RecName: Full=Transmembrane protein 244;
GN   Name=TMEM244; Synonyms=C6orf191;
//
ID   TM245_HUMAN             Reviewed;         911 AA.
AC   Q9H330; B4DSW7; Q5JTQ5; Q5SS43; Q6ZME3; Q8NDJ5; Q96CG6;
DE   RecName: Full=Transmembrane protein 245;
DE   AltName: Full=Protein CG-2;
GN   Name=TMEM245; Synonyms=C9orf5;
//
ID   TM246_HUMAN             Reviewed;         403 AA.
AC   Q9BRR3; Q49AQ4;
DE   RecName: Full=Transmembrane protein 246;
GN   Name=TMEM246; Synonyms=C9orf125;
//
ID   TM247_HUMAN             Reviewed;         219 AA.
AC   A6NEH6;
DE   RecName: Full=Transmembrane protein 247;
GN   Name=TMEM247;
//
ID   TM249_HUMAN             Reviewed;         235 AA.
AC   Q2WGJ8;
DE   RecName: Full=Transmembrane protein 249;
GN   Name=TMEM249; Synonyms=C8orfK29;
//
ID   TM248_HUMAN             Reviewed;         314 AA.
AC   Q9NWD8; Q53H07; Q96FR2;
DE   RecName: Full=Transmembrane protein 248;
GN   Name=TMEM248; Synonyms=C7orf42;
//
ID   TM251_HUMAN             Reviewed;         163 AA.
AC   Q8N6I4; J3KQ65; Q9Y4S5;
DE   RecName: Full=Transmembrane protein 251;
GN   Name=TMEM251; Synonyms=C14orf109;
//
ID   TM252_HUMAN             Reviewed;         170 AA.
AC   Q8N6L7;
DE   RecName: Full=Transmembrane protein 252;
GN   Name=TMEM252; Synonyms=C9orf71;
//
ID   TM253_HUMAN             Reviewed;         217 AA.
AC   P0C7T8;
DE   RecName: Full=Transmembrane protein 253;
GN   Name=TMEM253; Synonyms=C14orf176, C14orf95;
//
ID   TM254_HUMAN             Reviewed;         123 AA.
AC   Q8TBM7; D3DWC8; Q53HP4; Q5JTC0; Q5JTC1; Q6IA45; Q9H8S6;
DE   RecName: Full=Transmembrane protein 254;
GN   Name=TMEM254; Synonyms=C10orf57;
//
ID   TM257_HUMAN             Reviewed;         111 AA.
AC   O96002; Q14CW0;
DE   RecName: Full=Transmembrane protein 257;
GN   Name=TMEM257; Synonyms=CXorf1;
//
ID   TM256_HUMAN             Reviewed;         113 AA.
AC   Q8N2U0;
DE   RecName: Full=Transmembrane protein 256;
DE   Flags: Precursor;
GN   Name=TMEM256; Synonyms=C17orf61;
//
ID   TM258_HUMAN             Reviewed;          79 AA.
AC   P61165; A8K6L8; Q9D953; Q9Y2Q7;
DE   RecName: Full=Transmembrane protein 258;
GN   Name=TMEM258; Synonyms=C11orf10; ORFNames=HSPC005;
//
ID   TM260_HUMAN             Reviewed;         707 AA.
AC   Q9NX78; A8KAN4; B3KPF5; Q86XE1;
DE   RecName: Full=Transmembrane protein 260;
GN   Name=TMEM260; Synonyms=C14orf101;
//
ID   TM261_HUMAN             Reviewed;         116 AA.
AC   Q96GE9; A8K9B7; Q5T6Y9; Q9NT74;
DE   RecName: Full=Transmembrane protein 261;
GN   Name=TMEM261; Synonyms=C9orf123;
//
ID   TM263_HUMAN             Reviewed;         116 AA.
AC   Q8WUH6; B3KMN9;
DE   RecName: Full=Transmembrane protein 263;
GN   Name=TMEM263; Synonyms=C12orf23;
//
ID   TM262_HUMAN             Reviewed;         116 AA.
AC   E9PQX1;
DE   RecName: Full=Transmembrane protein 262;
GN   Name=TMEM262;
//
ID   TM2D1_HUMAN             Reviewed;         207 AA.
AC   Q9BX74; A6NDA8;
DE   RecName: Full=TM2 domain-containing protein 1;
DE   AltName: Full=Beta-amyloid-binding protein;
DE            Short=hBBP;
DE   Flags: Precursor;
GN   Name=TM2D1; Synonyms=BBP;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   TM2D2_HUMAN             Reviewed;         214 AA.
AC   Q9BX73; B2RBK4; D3DSX8; Q8N0X9;
DE   RecName: Full=TM2 domain-containing protein 2;
DE   AltName: Full=Beta-amyloid-binding protein-like protein 1;
DE            Short=BBP-like protein 1;
DE   Flags: Precursor;
GN   Name=TM2D2; Synonyms=BLP1;
//
ID   TM2D3_HUMAN             Reviewed;         247 AA.
AC   Q9BRN9; B2RDK9; Q9H046; Q9H651;
DE   RecName: Full=TM2 domain-containing protein 3;
DE   AltName: Full=Beta-amyloid-binding protein-like protein 2;
DE            Short=BBP-like protein 2;
DE   Flags: Precursor;
GN   Name=TM2D3; Synonyms=BLP2;
//
ID   TM38A_HUMAN             Reviewed;         299 AA.
AC   Q9H6F2; A8K9P9;
DE   RecName: Full=Trimeric intracellular cation channel type A;
DE            Short=TRIC-A;
DE            Short=TRICA;
DE   AltName: Full=Transmembrane protein 38A;
GN   Name=TMEM38A;
DR   GO; GO:0005267; F:potassium channel activity; TAS:BHF-UCL.
//
ID   TM38B_HUMAN             Reviewed;         291 AA.
AC   Q9NVV0; Q5JR63; Q5SVN5; Q5SVN6; Q5VTE2; Q6IA97;
DE   RecName: Full=Trimeric intracellular cation channel type B;
DE            Short=TRIC-B;
DE            Short=TRICB;
DE   AltName: Full=Transmembrane protein 38B;
GN   Name=TMEM38B; Synonyms=C9orf87;
DR   GO; GO:0005267; F:potassium channel activity; TAS:BHF-UCL.
//
ID   TM39A_HUMAN             Reviewed;         488 AA.
AC   Q9NV64; D3DN80; Q53FN4; Q53GI1; Q6PKB5;
DE   RecName: Full=Transmembrane protein 39A;
GN   Name=TMEM39A;
//
ID   TM39B_HUMAN             Reviewed;         492 AA.
AC   Q9GZU3; D3DPP4; Q6IA44;
DE   RecName: Full=Transmembrane protein 39B;
GN   Name=TMEM39B;
//
ID   TM40L_HUMAN             Reviewed;         308 AA.
AC   Q969M1; B7Z4U0; D3DVG9;
DE   RecName: Full=Mitochondrial import receptor subunit TOM40B;
DE   AltName: Full=Protein TOMM40-like;
GN   Name=TOMM40L; Synonyms=TOMM40B;
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TM41A_HUMAN             Reviewed;         264 AA.
AC   Q96HV5; A8K4B3; D3DNU2; Q6ZMJ0;
DE   RecName: Full=Transmembrane protein 41A;
DE   Flags: Precursor;
GN   Name=TMEM41A; ORFNames=UNQ168/PRO194;
//
ID   TM41B_HUMAN             Reviewed;         291 AA.
AC   Q5BJD5; D3DQU9; E9PP29; Q15055; Q4G0P0;
DE   RecName: Full=Transmembrane protein 41B;
GN   Name=TMEM41B; Synonyms=KIAA0033;
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
//
ID   TM45A_HUMAN             Reviewed;         275 AA.
AC   Q9NWC5; Q53YW5;
DE   RecName: Full=Transmembrane protein 45A;
DE   AltName: Full=DNA polymerase-transactivated protein 4;
DE   AltName: Full=Dermal papilla-derived protein 7;
GN   Name=TMEM45A; Synonyms=DERP7, DNAPTP4;
//
ID   TM45B_HUMAN             Reviewed;         275 AA.
AC   Q96B21; A8K2L8;
DE   RecName: Full=Transmembrane protein 45B;
GN   Name=TMEM45B;
//
ID   TM50A_HUMAN             Reviewed;         157 AA.
AC   O95807;
DE   RecName: Full=Transmembrane protein 50A;
DE   AltName: Full=Small membrane protein 1;
GN   Name=TMEM50A; Synonyms=SMP1; ORFNames=UNQ386/PRO718;
//
ID   TM50B_HUMAN             Reviewed;         158 AA.
AC   P56557; B2R4L4; D3DSF1; O60537; Q5PY47;
DE   RecName: Full=Transmembrane protein 50B;
DE   AltName: Full=HCV p7-trans-regulated protein 3;
GN   Name=TMEM50B; Synonyms=C21orf4; ORFNames=UNQ167/PRO193;
//
ID   TM52B_HUMAN             Reviewed;         183 AA.
AC   Q4KMG9; Q96NA7;
DE   RecName: Full=Transmembrane protein 52B;
DE   Flags: Precursor;
GN   Name=TMEM52B; Synonyms=C12orf59; ORFNames=UNQ5927/PRO19821;
//
ID   TM55A_HUMAN             Reviewed;         257 AA.
AC   Q8N4L2; B2R9H4; Q68CU2;
DE   RecName: Full=Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase;
DE            Short=Type 2 PtdIns-4,5-P2 4-Ptase;
DE            EC=3.1.3.78;
DE   AltName: Full=PtdIns-4,5-P2 4-Ptase II;
DE   AltName: Full=Transmembrane protein 55A;
GN   Name=TMEM55A;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   TM55B_HUMAN             Reviewed;         277 AA.
AC   Q86T03; B2RA35; Q86U09; Q8WUC0; Q9BU67; Q9NSU8;
DE   RecName: Full=Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase;
DE            Short=Type 1 PtdIns-4,5-P2 4-Ptase;
DE            EC=3.1.3.78;
DE   AltName: Full=PtdIns-4,5-P2 4-Ptase I;
DE   AltName: Full=Transmembrane protein 55B;
GN   Name=TMEM55B; Synonyms=C14orf9;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
//
ID   TM59L_HUMAN             Reviewed;         342 AA.
AC   Q9UK28;
DE   RecName: Full=Transmembrane protein 59-like;
DE   AltName: Full=Brain-specific membrane-anchored protein;
DE   Flags: Precursor;
GN   Name=TMEM59L; Synonyms=BSMAP, C19orf4;
//
ID   TM63A_HUMAN             Reviewed;         807 AA.
AC   O94886; Q53GI7; Q5TE96; Q8N2U2;
DE   RecName: Full=Transmembrane protein 63A;
GN   Name=TMEM63A; Synonyms=KIAA0489, KIAA0792;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   TM63B_HUMAN             Reviewed;         832 AA.
AC   Q5T3F8; B9EGU3; Q5T3F9; Q6AHX4; Q6P5A0; Q8N219; Q8NDE1; Q9NSG5;
DE   RecName: Full=Transmembrane protein 63B;
GN   Name=TMEM63B; Synonyms=C6orf110;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
//
ID   TM63C_HUMAN             Reviewed;         806 AA.
AC   Q9P1W3; B2RN22; B3KWJ5; Q86TS3; Q86TS4; Q9NSQ4; Q9P1W1;
DE   RecName: Full=Transmembrane protein 63C;
GN   Name=TMEM63C; Synonyms=C14orf171;
//
ID   TM6S1_HUMAN             Reviewed;         370 AA.
AC   Q9BZW5; A8K7T5; H3BU56; Q4U0U5;
DE   RecName: Full=Transmembrane 6 superfamily member 1;
GN   Name=TM6SF1;
//
ID   TM6S2_HUMAN             Reviewed;         377 AA.
AC   Q9BZW4; Q0IJ64;
DE   RecName: Full=Transmembrane 6 superfamily member 2;
GN   Name=TM6SF2;
//
ID   TM74B_HUMAN             Reviewed;         256 AA.
AC   Q9NUR3; D3DVW5;
DE   RecName: Full=Transmembrane protein 74B;
GN   Name=TMEM74B; Synonyms=C20orf46;
//
ID   TM7S3_HUMAN             Reviewed;         570 AA.
AC   Q9NS93; B3KMZ3; Q9NUS4;
DE   RecName: Full=Transmembrane 7 superfamily member 3;
DE   AltName: Full=Seven span transmembrane protein;
DE   Flags: Precursor;
GN   Name=TM7SF3;
//
ID   TM86A_HUMAN             Reviewed;         240 AA.
AC   Q8N2M4; Q96AJ0;
DE   RecName: Full=Lysoplasmalogenase-like protein TMEM86A;
DE   AltName: Full=Transmembrane protein 86A;
GN   Name=TMEM86A;
//
ID   TM86B_HUMAN             Reviewed;         226 AA.
AC   Q8N661;
DE   RecName: Full=Lysoplasmalogenase;
DE            EC=3.3.2.2;
DE            EC=3.3.2.5;
DE   AltName: Full=Transmembrane protein 86B;
GN   Name=TMEM86B;
DR   GO; GO:0047408; F:alkenylglycerophosphocholine hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0047409; F:alkenylglycerophosphoethanolamine hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0046485; P:ether lipid metabolic process; IDA:UniProtKB.
//
ID   TM87B_HUMAN             Reviewed;         555 AA.
AC   Q96K49; A8K2M9; Q1RLN2; Q53R54;
DE   RecName: Full=Transmembrane protein 87B;
DE   Flags: Precursor;
GN   Name=TMEM87B;
//
ID   TM87A_HUMAN             Reviewed;         555 AA.
AC   Q8NBN3; Q6NT77; Q8NCA4; Q9BS46; Q9P103; Q9Y3Y7;
DE   RecName: Full=Transmembrane protein 87A;
DE   Flags: Precursor;
GN   Name=TMEM87A; ORFNames=PSEC0094;
//
ID   TM88B_HUMAN             Reviewed;         163 AA.
AC   A6NKF7;
DE   RecName: Full=Transmembrane protein 88B;
GN   Name=TMEM88B;
//
ID   TM9S1_HUMAN             Reviewed;         606 AA.
AC   O15321; D3DS65; Q86SZ6; Q96FI8;
DE   RecName: Full=Transmembrane 9 superfamily member 1;
DE   AltName: Full=MP70 protein family member;
DE            Short=hMP70;
DE   Flags: Precursor;
GN   Name=TM9SF1;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   TM9S2_HUMAN             Reviewed;         663 AA.
AC   Q99805; A8K399; Q2TAY5;
DE   RecName: Full=Transmembrane 9 superfamily member 2;
DE   AltName: Full=p76;
DE   Flags: Precursor;
GN   Name=TM9SF2;
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   TM9S3_HUMAN             Reviewed;         589 AA.
AC   Q9HD45; Q5TB57; Q6UWE7; Q9NWL8; Q9P0G9; Q9UHW8;
DE   RecName: Full=Transmembrane 9 superfamily member 3;
DE   AltName: Full=EP70-P-iso;
DE   AltName: Full=SM-11044-binding protein;
DE   Flags: Precursor;
GN   Name=TM9SF3; Synonyms=SMBP; ORFNames=UNQ245/PRO282;
//
ID   TM9S4_HUMAN             Reviewed;         642 AA.
AC   Q92544; B0QYT7; Q9NUA3;
DE   RecName: Full=Transmembrane 9 superfamily member 4;
DE   Flags: Precursor;
GN   Name=TM9SF4; Synonyms=KIAA0255;
//
ID   TMA16_HUMAN             Reviewed;         203 AA.
AC   Q96EY4; Q0P6E4; Q0P6J1; Q9NUR7;
DE   RecName: Full=Translation machinery-associated protein 16;
GN   Name=TMA16; Synonyms=C4orf43;
//
ID   TMA7_HUMAN              Reviewed;          64 AA.
AC   Q9Y2S6; Q9P052;
DE   RecName: Full=Translation machinery-associated protein 7;
DE   AltName: Full=Coiled-coil domain-containing protein 72;
GN   Name=TMA7; Synonyms=CCDC72; ORFNames=HSPC016, HSPC330;
//
ID   TMC1_HUMAN              Reviewed;         760 AA.
AC   Q8TDI8; A8MVZ2; B1AM91;
DE   RecName: Full=Transmembrane channel-like protein 1;
DE   AltName: Full=Transmembrane cochlear-expressed protein 1;
GN   Name=TMC1;
DR   GO; GO:0060117; P:auditory receptor cell development; IEA:Ensembl.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0060005; P:vestibular reflex; IEA:Ensembl.
//
ID   TMC2_HUMAN              Reviewed;         906 AA.
AC   Q8TDI7; Q5JXT0; Q5JXT1; Q6UWW4; Q6ZS41; Q8N9F3; Q9BYN2; Q9BYN3;
AC   Q9BYN4; Q9BYN5;
DE   RecName: Full=Transmembrane channel-like protein 2;
DE   AltName: Full=Transmembrane cochlear-expressed protein 2;
GN   Name=TMC2; Synonyms=C20orf145; ORFNames=UNQ907/PRO1928;
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0060005; P:vestibular reflex; IEA:Ensembl.
//
ID   TMC3_HUMAN              Reviewed;        1100 AA.
AC   Q7Z5M5; A2RTY2; B2RXJ3; Q7Z405;
DE   RecName: Full=Transmembrane channel-like protein 3;
GN   Name=TMC3;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   TMC4_HUMAN              Reviewed;         712 AA.
AC   Q7Z404; Q7Z5M3; Q8N5E4; Q8TBS7;
DE   RecName: Full=Transmembrane channel-like protein 4;
GN   Name=TMC4;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   TMC5A_HUMAN             Reviewed;         288 AA.
AC   Q8N6Q1; Q8NA63;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 5A;
GN   Name=TMCO5A; Synonyms=TMCO5;
//
ID   TMC5B_HUMAN             Reviewed;         307 AA.
AC   A8MYB1;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 5B;
GN   Name=TMCO5B;
//
ID   TMC5_HUMAN              Reviewed;        1006 AA.
AC   Q6UXY8; Q68DK8; Q8IY20; Q8NHV6; Q9H8I7;
DE   RecName: Full=Transmembrane channel-like protein 5;
GN   Name=TMC5; ORFNames=UNQ8238/PRO33604;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   TMC6_HUMAN              Reviewed;         805 AA.
AC   Q7Z403; O43284; Q45VJ2; Q8IU98; Q8IUI7; Q8IWU8; Q8TEQ7; Q9HAG5;
DE   RecName: Full=Transmembrane channel-like protein 6;
DE   AltName: Full=Epidermodysplasia verruciformis protein 1;
DE   AltName: Full=Protein LAK-4;
GN   Name=TMC6; Synonyms=EVER1, EVIN1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   TMC7_HUMAN              Reviewed;         723 AA.
AC   Q7Z402; E7ERB6; Q5H9Q8; Q7Z5M4; Q86WX0; Q9H766;
DE   RecName: Full=Transmembrane channel-like protein 7;
GN   Name=TMC7;
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   TMC8_HUMAN              Reviewed;         726 AA.
AC   Q8IU68; Q2YDC0; Q8IWU7; Q8N358; Q8NF04;
DE   RecName: Full=Transmembrane channel-like protein 8;
DE   AltName: Full=Epidermodysplasia verruciformis protein 2;
GN   Name=TMC8; Synonyms=EVER2, EVIN2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProt.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0032091; P:negative regulation of protein binding; IDA:UniProt.
DR   GO; GO:0032460; P:negative regulation of protein oligomerization; IDA:UniProt.
DR   GO; GO:0001558; P:regulation of cell growth; IDA:UniProt.
DR   GO; GO:1902041; P:regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProt.
DR   GO; GO:0055069; P:zinc ion homeostasis; IDA:UniProt.
//
ID   TMCC1_HUMAN             Reviewed;         653 AA.
AC   O94876; A8K5Y3; B4DE04; Q68E06; Q8IXM8;
DE   RecName: Full=Transmembrane and coiled-coil domains protein 1;
GN   Name=TMCC1; Synonyms=KIAA0779;
//
ID   TMCC2_HUMAN             Reviewed;         709 AA.
AC   O75069; A2RRH3; B7Z1P7; Q6ZN09;
DE   RecName: Full=Transmembrane and coiled-coil domains protein 2;
DE   AltName: Full=Cerebral protein 11;
GN   Name=TMCC2; Synonyms=KIAA0481; ORFNames=hucep-11;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TMCC3_HUMAN             Reviewed;         477 AA.
AC   Q9ULS5; Q8IWB2;
DE   RecName: Full=Transmembrane and coiled-coil domains protein 3;
GN   Name=TMCC3; Synonyms=KIAA1145;
//
ID   TMCO1_HUMAN             Reviewed;         188 AA.
AC   Q9UM00; B2REA0; O75545; Q9BZS3; Q9BZU8;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 1;
DE   AltName: Full=Transmembrane and coiled-coil domains protein 4;
DE   AltName: Full=Xenogeneic cross-immune protein PCIA3;
GN   Name=TMCO1; Synonyms=TMCC4; ORFNames=PNAS-10, PNAS-136, UNQ151/PRO177;
//
ID   TMCO3_HUMAN             Reviewed;         677 AA.
AC   Q6UWJ1; Q5JSB1; Q6NUN1; Q8NG29; Q8TCI6; Q96EA6; Q9NWT2;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 3;
DE   AltName: Full=Putative LAG1-interacting protein;
DE   Flags: Precursor;
GN   Name=TMCO3; Synonyms=C13orf11; ORFNames=UNQ2419/PRO4976;
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
//
ID   TMCO4_HUMAN             Reviewed;         634 AA.
AC   Q5TGY1; Q5TGY2; Q6MZN5; Q7Z6K6; Q9UQP4; Q9Y3K1;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 4;
GN   Name=TMCO4;
//
ID   TMED1_HUMAN             Reviewed;         227 AA.
AC   Q13445;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 1;
DE   AltName: Full=Interleukin-1 receptor-like 1 ligand;
DE   AltName: Full=Putative T1/ST2 receptor-binding protein;
DE   AltName: Full=p24 family protein gamma-1;
DE            Short=Tp24;
DE            Short=p24gamma1;
DE   Flags: Precursor;
GN   Name=TMED1; Synonyms=IL1RL1L, IL1RL1LG;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TMCO2_HUMAN             Reviewed;         182 AA.
AC   Q7Z6W1;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 2;
GN   Name=TMCO2;
//
ID   TMCO6_HUMAN             Reviewed;         493 AA.
AC   Q96DC7; Q9BUU0; Q9P198;
DE   RecName: Full=Transmembrane and coiled-coil domain-containing protein 6;
GN   Name=TMCO6; ORFNames=PRO1580;
DR   GO; GO:0008565; F:protein transporter activity; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
//
ID   TMED3_HUMAN             Reviewed;         217 AA.
AC   Q9Y3Q3; A8K069; B4DN05; Q2T9F8;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 3;
DE   AltName: Full=Membrane protein p24B;
DE   AltName: Full=p24 family protein gamma-4;
DE            Short=p24gamma4;
DE   AltName: Full=p26;
DE   Flags: Precursor;
GN   Name=TMED3; Synonyms=C15orf22; ORFNames=UNQ5357/PRO1078;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TMED2_HUMAN             Reviewed;         201 AA.
AC   Q15363;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 2;
DE   AltName: Full=Membrane protein p24A;
DE   AltName: Full=p24;
DE   AltName: Full=p24 family protein beta-1;
DE            Short=p24beta1;
DE   Flags: Precursor;
GN   Name=TMED2; Synonyms=RNP24;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035459; P:cargo loading into vesicle; TAS:UniProtKB.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:UniProtKB.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:UniProtKB.
DR   GO; GO:0048598; P:embryonic morphogenesis; IEA:Ensembl.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0001893; P:maternal placenta development; IEA:Ensembl.
DR   GO; GO:0034260; P:negative regulation of GTPase activity; IDA:UniProtKB.
DR   GO; GO:0072661; P:protein targeting to plasma membrane; IDA:UniProtKB.
//
ID   TMED5_HUMAN             Reviewed;         229 AA.
AC   Q9Y3A6; B1AKT4; B2R703; D3DT38; Q96AX8;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 5;
DE   AltName: Full=p24 family protein gamma-2;
DE            Short=p24gamma2;
DE   AltName: Full=p28;
DE   Flags: Precursor;
GN   Name=TMED5; ORFNames=CGI-100, UNQ397/PRO733;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0090161; P:Golgi ribbon formation; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TMED4_HUMAN             Reviewed;         227 AA.
AC   Q7Z7H5; A4D2K8; B4DFJ4; Q56VW3; Q7Z432; Q8N2P6;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 4;
DE   AltName: Full=Endoplasmic reticulum stress-response protein 25;
DE            Short=ERS25;
DE   AltName: Full=GMP25iso;
DE   AltName: Full=Putative NF-kappa-B-activating protein 156;
DE   AltName: Full=p24 family protein alpha-3;
DE            Short=p24alpha3;
DE   Flags: Precursor;
GN   Name=TMED4; Synonyms=ERS25;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TMED6_HUMAN             Reviewed;         240 AA.
AC   Q8WW62; Q6UXN5;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 6;
DE   AltName: Full=p24 family protein gamma-5;
DE            Short=p24gamma5;
DE   Flags: Precursor;
GN   Name=TMED6; ORFNames=UNQ9146/PRO34237;
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   TMED7_HUMAN             Reviewed;         224 AA.
AC   Q9Y3B3; Q8NBU8; Q8WUU6; Q96K51;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 7;
DE   AltName: Full=p24 family protein gamma-3;
DE            Short=p24gamma3;
DE   AltName: Full=p27;
DE   Flags: Precursor;
GN   Name=TMED7; ORFNames=CGI-109;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TMED8_HUMAN             Reviewed;         325 AA.
AC   Q6PL24; B3KTI6; Q3MJB0; Q9P1V9;
DE   RecName: Full=Protein TMED8;
GN   Name=TMED8; Synonyms=FAM15B; ORFNames=L10;
DR   GO; GO:0006810; P:transport; IEA:InterPro.
//
ID   TMED9_HUMAN             Reviewed;         235 AA.
AC   Q9BVK6; Q14437; Q8WZ61;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 9;
DE   AltName: Full=GMP25;
DE   AltName: Full=Glycoprotein 25L2;
DE   AltName: Full=p24 family protein alpha-2;
DE            Short=p24alpha2;
DE   AltName: Full=p25;
DE   Flags: Precursor;
GN   Name=TMED9; Synonyms=GP25L2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019905; F:syntaxin binding; IPI:UniProtKB.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; IMP:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0010638; P:positive regulation of organelle organization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TMEDA_HUMAN             Reviewed;         219 AA.
AC   P49755; B2R605; Q15602; Q16536; Q86TC2; Q86TS5;
DE   RecName: Full=Transmembrane emp24 domain-containing protein 10;
DE   AltName: Full=21 kDa transmembrane-trafficking protein;
DE   AltName: Full=S31III125;
DE            Short=S31I125;
DE   AltName: Full=Tmp-21-I;
DE   AltName: Full=Transmembrane protein Tmp21;
DE   AltName: Full=p23;
DE   AltName: Full=p24 family protein delta-1;
DE            Short=p24delta1;
DE   AltName: Full=p24delta;
DE   Flags: Precursor;
GN   Name=TMED10; Synonyms=TMP21;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019905; F:syntaxin binding; IPI:UniProtKB.
DR   GO; GO:0034205; P:beta-amyloid formation; IMP:UniProtKB.
DR   GO; GO:0035459; P:cargo loading into vesicle; TAS:UniProtKB.
DR   GO; GO:0048205; P:COPI coating of Golgi vesicle; TAS:UniProtKB.
DR   GO; GO:0035964; P:COPI-coated vesicle budding; IDA:UniProtKB.
DR   GO; GO:0048208; P:COPII vesicle coating; TAS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051259; P:protein oligomerization; IEA:Ensembl.
DR   GO; GO:0045055; P:regulated secretory pathway; ISS:HGNC.
DR   GO; GO:0001101; P:response to acid; IEA:Ensembl.
DR   GO; GO:0043279; P:response to alkaloid; IEA:Ensembl.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISS:UniProtKB.
DR   GO; GO:0048199; P:vesicle targeting, to, from or within Golgi; ISS:HGNC.
//
ID   TMEM2_HUMAN             Reviewed;        1383 AA.
AC   Q9UHN6; A6H8W9; B2RTQ6; Q5T838; Q5T839; Q5T840; Q5T841; Q8NBP6;
AC   Q9P2D5;
DE   RecName: Full=Transmembrane protein 2;
GN   Name=TMEM2; Synonyms=KIAA1412;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   TMEM5_HUMAN             Reviewed;         443 AA.
AC   Q9Y2B1; A8K017; Q6PKD6;
DE   RecName: Full=Transmembrane protein 5;
GN   Name=TMEM5;
//
ID   TMEM9_HUMAN             Reviewed;         183 AA.
AC   Q9P0T7; B1ALM6; Q96NQ9; Q9BQF5;
DE   RecName: Full=Transmembrane protein 9;
DE   AltName: Full=Dermal papilla-derived protein 4;
DE   Flags: Precursor;
GN   Name=TMEM9; Synonyms=DERP4;
GN   ORFNames=HSPC186, PSEC0012, UNQ631/PRO1248;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   TMF1_HUMAN              Reviewed;        1093 AA.
AC   P82094; B7ZLJ2; Q17R87; Q59GK0;
DE   RecName: Full=TATA element modulatory factor;
DE            Short=TMF;
DE   AltName: Full=Androgen receptor coactivator 160 kDa protein;
DE   AltName: Full=Androgen receptor-associated protein of 160 kDa;
GN   Name=TMF1; Synonyms=ARA160;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003712; F:transcription cofactor activity; TAS:ProtInc.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0033327; P:Leydig cell differentiation; IEA:Ensembl.
DR   GO; GO:0032275; P:luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:2000845; P:positive regulation of testosterone secretion; IEA:Ensembl.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0030317; P:sperm motility; IEA:Ensembl.
DR   GO; GO:0007289; P:spermatid nucleus differentiation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TMIG2_HUMAN             Reviewed;         282 AA.
AC   Q96BF3; Q6UW59;
DE   RecName: Full=Transmembrane and immunoglobulin domain-containing protein 2;
DE   AltName: Full=CD28 homolog;
DE   AltName: Full=Immunoglobulin and proline-rich receptor 1;
DE            Short=IGPR-1;
DE   Flags: Precursor;
GN   Name=TMIGD2; Synonyms=CD28H, IGPR1; ORFNames=UNQ3059/PRO9879;
DR   GO; GO:0015026; F:coreceptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IDA:GOC.
DR   GO; GO:0031295; P:T cell costimulation; IDA:UniProtKB.
//
ID   TMG1_HUMAN              Reviewed;         218 AA.
AC   O14668; B2R7A3; C9JXL7; D3DWA9; Q5JT66;
DE   RecName: Full=Transmembrane gamma-carboxyglutamic acid protein 1;
DE   AltName: Full=Proline-rich gamma-carboxyglutamic acid protein 1;
DE            Short=Proline-rich Gla protein 1;
DE   Flags: Precursor;
GN   Name=PRRG1; Synonyms=PRGP1, TMG1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   TMG4_HUMAN              Reviewed;         226 AA.
AC   Q9BZD6;
DE   RecName: Full=Transmembrane gamma-carboxyglutamic acid protein 4;
DE   AltName: Full=Proline-rich gamma-carboxyglutamic acid protein 4;
DE            Short=Proline-rich Gla protein 4;
DE   Flags: Precursor;
GN   Name=PRRG4; Synonyms=PRGP4, TMG4;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   TMG3_HUMAN              Reviewed;         231 AA.
AC   Q9BZD7; A1A523; A1A575; Q8N2N6;
DE   RecName: Full=Transmembrane gamma-carboxyglutamic acid protein 3;
DE   AltName: Full=Proline-rich gamma-carboxyglutamic acid protein 3;
DE            Short=Proline-rich Gla protein 3;
DE   Flags: Precursor;
GN   Name=PRRG3; Synonyms=PRGP3, TMG3;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   TMIG1_HUMAN             Reviewed;         262 AA.
AC   Q6UXZ0; A8K2K1; Q6ZMC6;
DE   RecName: Full=Transmembrane and immunoglobulin domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=TMIGD1; Synonyms=TMIGD; ORFNames=UNQ9372/PRO34164;
//
ID   TMIE_HUMAN              Reviewed;         156 AA.
AC   Q8NEW7; A0AV93; A8K0R0;
DE   RecName: Full=Transmembrane inner ear expressed protein;
DE   Flags: Precursor;
GN   Name=TMIE;
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   TMG2_HUMAN              Reviewed;         202 AA.
AC   O14669; Q6IBF8;
DE   RecName: Full=Transmembrane gamma-carboxyglutamic acid protein 2;
DE   AltName: Full=Proline-rich gamma-carboxyglutamic acid protein 2;
DE            Short=Proline-rich Gla protein 2;
DE   Flags: Precursor;
GN   Name=PRRG2; Synonyms=PRGP2, TMG2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   TMHS_HUMAN              Reviewed;         219 AA.
AC   Q8TAF8; B3KX66;
DE   RecName: Full=Tetraspan membrane protein of hair cell stereocilia;
DE   AltName: Full=Lipoma HMGIC fusion partner-like 5 protein;
GN   Name=LHFPL5; Synonyms=TMHS;
DR   GO; GO:0060088; P:auditory receptor cell stereocilium organization; IEA:Ensembl.
DR   GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
//
ID   TMLH_HUMAN              Reviewed;         421 AA.
AC   Q9NVH6; A8K6M9; B4E3R3; Q5TZB5; Q6IA90; Q8TBT0;
DE   RecName: Full=Trimethyllysine dioxygenase, mitochondrial;
DE            EC=1.14.11.8;
DE   AltName: Full=Epsilon-trimethyllysine 2-oxoglutarate dioxygenase;
DE   AltName: Full=Epsilon-trimethyllysine hydroxylase;
DE   AltName: Full=TML hydroxylase;
DE   AltName: Full=TML-alpha-ketoglutarate dioxygenase;
DE            Short=TML dioxygenase;
DE            Short=TMLD;
DE   Flags: Precursor;
GN   Name=TMLHE; Synonyms=TMLH;
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
DR   GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:Ensembl.
DR   GO; GO:0050353; F:trimethyllysine dioxygenase activity; IDA:BHF-UCL.
DR   GO; GO:0045329; P:carnitine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0051354; P:negative regulation of oxidoreductase activity; IDA:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TMM17_HUMAN             Reviewed;         198 AA.
AC   Q86X19; Q53QP7; Q53R98;
DE   RecName: Full=Transmembrane protein 17;
GN   Name=TMEM17;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   TMM11_HUMAN             Reviewed;         192 AA.
AC   P17152; Q53YB2;
DE   RecName: Full=Transmembrane protein 11, mitochondrial;
DE   AltName: Full=Protein PM1;
DE   AltName: Full=Protein PMI;
GN   Name=TMEM11; Synonyms=C17orf35, PM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
//
ID   TMM18_HUMAN             Reviewed;         140 AA.
AC   Q96B42; D6W4X9; Q8N5H2; Q9NTH3;
DE   RecName: Full=Transmembrane protein 18;
GN   Name=TMEM18;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TMM19_HUMAN             Reviewed;         336 AA.
AC   Q96HH6; B2RDL2; Q53FY3; Q9NV41;
DE   RecName: Full=Transmembrane protein 19;
GN   Name=TMEM19;
//
ID   TMM26_HUMAN             Reviewed;         368 AA.
AC   Q6ZUK4; Q6ZVM0; Q8IVN9;
DE   RecName: Full=Transmembrane protein 26;
GN   Name=TMEM26;
//
ID   TMM25_HUMAN             Reviewed;         366 AA.
AC   Q86YD3; A8K8J4; B0YJA6; B0YJA7; B0YJA9; G5E9U4; Q6UW89; Q86UA7;
AC   Q8NBL5; Q96KA6; Q96MW9;
DE   RecName: Full=Transmembrane protein 25;
DE   Flags: Precursor;
GN   Name=TMEM25; ORFNames=UNQ2531/PRO6030;
//
ID   TMM31_HUMAN             Reviewed;         168 AA.
AC   Q5JXX7; Q8NHR4;
DE   RecName: Full=Transmembrane protein 31;
GN   Name=TMEM31;
//
ID   TMM27_HUMAN             Reviewed;         222 AA.
AC   Q9HBJ8; B2R9M1; Q6UW07;
DE   RecName: Full=Collectrin;
DE   AltName: Full=Transmembrane protein 27;
DE   Flags: Precursor;
GN   Name=TMEM27; ORFNames=UNQ679/PRO1312;
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008241; F:peptidyl-dipeptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:UniProt.
DR   GO; GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IDA:UniProt.
DR   GO; GO:0035543; P:positive regulation of SNARE complex assembly; IDA:UniProt.
//
ID   TMM33_HUMAN             Reviewed;         247 AA.
AC   P57088; B3KSS8; Q9H953;
DE   RecName: Full=Transmembrane protein 33;
DE   AltName: Full=Protein DB83;
GN   Name=TMEM33; Synonyms=DB83;
//
ID   TMM40_HUMAN             Reviewed;         233 AA.
AC   Q8WWA1; Q8NAL4; Q9NUZ4;
DE   RecName: Full=Transmembrane protein 40;
GN   Name=TMEM40;
//
ID   TMM35_HUMAN             Reviewed;         167 AA.
AC   Q53FP2; Q9H7Y3;
DE   RecName: Full=Transmembrane protein 35;
GN   Name=TMEM35;
//
ID   TMM42_HUMAN             Reviewed;         159 AA.
AC   Q69YG0; Q8WUQ6;
DE   RecName: Full=Transmembrane protein 42;
GN   Name=TMEM42;
//
ID   TMM43_HUMAN             Reviewed;         400 AA.
AC   Q9BTV4; Q7L4N5; Q8NC30; Q96A63; Q96F19; Q96JX0; Q9H076;
DE   RecName: Full=Transmembrane protein 43;
DE   AltName: Full=Protein LUMA;
GN   Name=TMEM43; ORFNames=UNQ2564/PRO6244;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   TMM44_HUMAN             Reviewed;         475 AA.
AC   Q2T9K0; A1L3V7; B7ZLZ5; B7ZLZ6; C9JJ62; E9PGA9; Q0P6F7; Q6ZT47;
AC   Q8IXR1; Q8N4G3;
DE   RecName: Full=Transmembrane protein 44;
GN   Name=TMEM44;
//
ID   TMM47_HUMAN             Reviewed;         181 AA.
AC   Q9BQJ4; Q5JR44;
DE   RecName: Full=Transmembrane protein 47;
DE   AltName: Full=Brain cell membrane protein 1;
DE   AltName: Full=Transmembrane 4 superfamily member 10;
GN   Name=TMEM47; Synonyms=BCMP1, TM4SF10;
//
ID   TMM51_HUMAN             Reviewed;         253 AA.
AC   Q9NW97; A8K819;
DE   RecName: Full=Transmembrane protein 51;
GN   Name=TMEM51; Synonyms=C1orf72;
//
ID   TMM52_HUMAN             Reviewed;         209 AA.
AC   Q8NDY8; Q4VXS6; Q6UX25;
DE   RecName: Full=Transmembrane protein 52;
DE   Flags: Precursor;
GN   Name=TMEM52; ORFNames=UNQ3048/PRO9864;
//
ID   TMM53_HUMAN             Reviewed;         277 AA.
AC   Q6P2H8; B4DKG0; Q5JPH2; Q6IA07; Q9H6E2;
DE   RecName: Full=Transmembrane protein 53;
GN   Name=TMEM53;
//
ID   TMM54_HUMAN             Reviewed;         222 AA.
AC   Q969K7; Q6UV18; Q8IVD0; Q9UM12;
DE   RecName: Full=Transmembrane protein 54;
DE   AltName: Full=Beta-casein-like protein;
DE   AltName: Full=Protein CAC-1;
GN   Name=TMEM54; Synonyms=BCLP, CAC1;
//
ID   TMM56_HUMAN             Reviewed;         263 AA.
AC   Q96MV1; B2RPI2; D3DT48;
DE   RecName: Full=Transmembrane protein 56;
GN   Name=TMEM56;
//
ID   TMM59_HUMAN             Reviewed;         323 AA.
AC   Q9BXS4; B3KQL7; O75393; Q4VBP9; Q5T705; Q96KX7;
DE   RecName: Full=Transmembrane protein 59;
DE   AltName: Full=Liver membrane-bound protein;
DE   Flags: Precursor;
GN   Name=TMEM59; Synonyms=C1orf8; ORFNames=HSPC001, UNQ169/PRO195;
DR   GO; GO:0004175; F:endopeptidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0090005; P:negative regulation of establishment of protein localization to plasma membrane; IDA:UniProt.
DR   GO; GO:0090285; P:negative regulation of protein glycosylation in Golgi; IDA:UniProt.
DR   GO; GO:0010955; P:negative regulation of protein processing; IDA:UniProt.
DR   GO; GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.
//
ID   TMM61_HUMAN             Reviewed;         210 AA.
AC   Q8N0U2;
DE   RecName: Full=Transmembrane protein 61;
GN   Name=TMEM61;
//
ID   TMM60_HUMAN             Reviewed;         133 AA.
AC   Q9H2L4; A4D1C3; Q86UM0;
DE   RecName: Full=Transmembrane protein 60;
GN   Name=TMEM60; Synonyms=C7orf35; ORFNames=DC32;
//
ID   TMM64_HUMAN             Reviewed;         380 AA.
AC   Q6YI46; B4DUC0; F5GXM4; Q2HIZ7; Q8N3G6;
DE   RecName: Full=Transmembrane protein 64;
GN   Name=TMEM64;
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0043462; P:regulation of ATPase activity; IEA:Ensembl.
//
ID   TMM62_HUMAN             Reviewed;         643 AA.
AC   Q0P6H9; Q6I9Y5; Q9H5J6;
DE   RecName: Full=Transmembrane protein 62;
GN   Name=TMEM62;
//
ID   TMM65_HUMAN             Reviewed;         240 AA.
AC   Q6PI78; Q8N5G8; Q8WVK5;
DE   RecName: Full=Transmembrane protein 65;
GN   Name=TMEM65;
//
ID   TMM68_HUMAN             Reviewed;         324 AA.
AC   Q96MH6; Q658X6; Q8WUD2;
DE   RecName: Full=Transmembrane protein 68;
GN   Name=TMEM68;
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
//
ID   TMM69_HUMAN             Reviewed;         247 AA.
AC   Q5SWH9; Q3SWW5; Q7Z2G0; Q9P0P9;
DE   RecName: Full=Transmembrane protein 69;
GN   Name=TMEM69; Synonyms=C1orf154; ORFNames=HSPC229;
//
ID   TMM71_HUMAN             Reviewed;         295 AA.
AC   Q6P5X7; Q3KRC2; Q8WVZ4; Q96LX9;
DE   RecName: Full=Transmembrane protein 71;
GN   Name=TMEM71;
//
ID   TMM70_HUMAN             Reviewed;         260 AA.
AC   Q9BUB7; E9PDY9; Q9NWY5;
DE   RecName: Full=Transmembrane protein 70, mitochondrial;
DE   Flags: Precursor;
GN   Name=TMEM70;
DR   GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IMP:UniProtKB.
//
ID   TMM72_HUMAN             Reviewed;         275 AA.
AC   A0PK05; A1L181; Q5T740;
DE   RecName: Full=Transmembrane protein 72;
DE   AltName: Full=Kidney-specific secretory protein of 37 kDa;
GN   Name=TMEM72; Synonyms=C10orf127, KSP37;
//
ID   TMM74_HUMAN             Reviewed;         305 AA.
AC   Q96NL1;
DE   RecName: Full=Transmembrane protein 74;
GN   Name=TMEM74;
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
//
ID   TMM78_HUMAN             Reviewed;         136 AA.
AC   Q5T7P6; Q8N802;
DE   RecName: Full=Transmembrane protein 78;
GN   Name=TMEM78;
//
ID   TMM75_HUMAN             Reviewed;         138 AA.
AC   Q8N9X5; B2RPD6; B9EH93;
DE   RecName: Full=Transmembrane protein 75;
GN   Name=TMEM75;
//
ID   TMM80_HUMAN             Reviewed;         168 AA.
AC   Q96HE8; A8MQ01; A8MXY8; B7WNU5;
DE   RecName: Full=Transmembrane protein 80;
GN   Name=TMEM80;
//
ID   TMM79_HUMAN             Reviewed;         394 AA.
AC   Q9BSE2; B2RE22; D3DVB8;
DE   RecName: Full=Transmembrane protein 79;
DE   AltName: Full=Mattrin;
GN   Name=TMEM79; Synonyms=MATT;
DR   GO; GO:0002070; P:epithelial cell maturation; ISS:UniProtKB.
DR   GO; GO:0061436; P:establishment of skin barrier; ISS:UniProtKB.
DR   GO; GO:0045684; P:positive regulation of epidermis development; ISS:UniProtKB.
DR   GO; GO:0045055; P:regulated secretory pathway; ISS:UniProtKB.
//
ID   TMM81_HUMAN             Reviewed;         255 AA.
AC   Q6P7N7; Q6UVZ4;
DE   RecName: Full=Transmembrane protein 81;
DE   Flags: Precursor;
GN   Name=TMEM81; ORFNames=UNQ2788/PRO7178;
//
ID   TMM82_HUMAN             Reviewed;         343 AA.
AC   A0PJX8; B2RP27; Q5VVD4;
DE   RecName: Full=Transmembrane protein 82;
GN   Name=TMEM82;
//
ID   TMM83_HUMAN             Reviewed;         136 AA.
AC   Q96N35;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00052;
DE   AltName: Full=Putative transmembrane protein 83;
GN   Name=LINC00052; Synonyms=NCRNA00052, TMEM83;
//
ID   TMM88_HUMAN             Reviewed;         159 AA.
AC   Q6PEY1;
DE   RecName: Full=Transmembrane protein 88;
GN   Name=TMEM88; Synonyms=TMEM88A;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TMM8A_HUMAN             Reviewed;         771 AA.
AC   Q9HCN3; D3DU49; Q4TT35; Q8WU24; Q96S25; Q9BR03; Q9BT97; Q9H7B9;
DE   RecName: Full=Transmembrane protein 8A;
DE   AltName: Full=Protein M83;
DE   AltName: Full=Transmembrane protein 6;
DE   AltName: Full=Transmembrane protein 8;
DE   Flags: Precursor;
GN   Name=TMEM8A; Synonyms=TMEM6, TMEM8;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
//
ID   TMM89_HUMAN             Reviewed;         159 AA.
AC   A2RUT3;
DE   RecName: Full=Transmembrane protein 89;
DE   Flags: Precursor;
GN   Name=TMEM89;
//
ID   TMM8B_HUMAN             Reviewed;         472 AA.
AC   A6NDV4; B3KQF3; O75539; Q49AB1; Q4KMX5; Q5TCW5; Q9HBY2; Q9P0U7;
DE   RecName: Full=Transmembrane protein 8B;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 6 protein;
DE   AltName: Full=Protein NAG-5;
DE   AltName: Full=Protein NGX6;
GN   Name=TMEM8B; Synonyms=C9orf127, NGX6;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:HGNC.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; TAS:HGNC.
//
ID   TMM8C_HUMAN             Reviewed;         221 AA.
AC   A6NI61;
DE   RecName: Full=Protein myomaker;
DE   AltName: Full=Transmembrane protein 226;
DE   AltName: Full=Transmembrane protein 8C;
GN   Name=TMEM8C; Synonyms=TMEM226;
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0007520; P:myoblast fusion; ISS:UniProtKB.
DR   GO; GO:0045026; P:plasma membrane fusion; ISS:UniProtKB.
//
ID   TMM91_HUMAN             Reviewed;         172 AA.
AC   Q6ZNR0; C9J9D1; C9JZ62; C9K046; Q6P434;
DE   RecName: Full=Transmembrane protein 91;
DE   AltName: Full=Dispanin subfamily C member 3;
DE            Short=DSPC3;
GN   Name=TMEM91;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   TMM92_HUMAN             Reviewed;         159 AA.
AC   Q6UXU6; Q8NBF0;
DE   RecName: Full=Transmembrane protein 92;
DE   Flags: Precursor;
GN   Name=TMEM92; ORFNames=UNQ5801/PRO19608;
//
ID   TMM95_HUMAN             Reviewed;         176 AA.
AC   Q3KNT9; B7WPI7; Q6UXT3; Q8IW68;
DE   RecName: Full=Transmembrane protein 95;
DE   Flags: Precursor;
GN   Name=TMEM95; ORFNames=UNQ9390/PRO34281;
//
ID   TMM97_HUMAN             Reviewed;         176 AA.
AC   Q5BJF2; B4DS02; Q07823;
DE   RecName: Full=Transmembrane protein 97;
DE   AltName: Full=Protein MAC30;
GN   Name=TMEM97; Synonyms=MAC30;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042632; P:cholesterol homeostasis; IDA:UniProtKB.
DR   GO; GO:0001558; P:regulation of cell growth; NAS:UniProtKB.
//
ID   TMM98_HUMAN             Reviewed;         226 AA.
AC   Q9Y2Y6; E1P631; Q9UFK2;
DE   RecName: Full=Transmembrane protein 98;
DE   AltName: Full=Protein TADA1;
GN   Name=TMEM98; ORFNames=UNQ536/PRO1079;
//
ID   TMM99_HUMAN             Reviewed;         258 AA.
AC   Q8N816; B4DQ34; Q96BP9;
DE   RecName: Full=Transmembrane protein 99;
DE   Flags: Precursor;
GN   Name=TMEM99;
//
ID   TMM9B_HUMAN             Reviewed;         198 AA.
AC   Q9NQ34;
DE   RecName: Full=Transmembrane protein 9B;
DE   Flags: Precursor;
GN   Name=TMEM9B; Synonyms=C11orf15; ORFNames=UNQ712/PRO1375;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TMOD1_HUMAN             Reviewed;         359 AA.
AC   P28289; B2RB77; Q9BUF1;
DE   RecName: Full=Tropomodulin-1;
DE   AltName: Full=Erythrocyte tropomodulin;
DE            Short=E-Tmod;
GN   Name=TMOD1; Synonyms=D9S57E, TMOD;
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0030239; P:myofibril assembly; IEA:Ensembl.
//
ID   TMOD2_HUMAN             Reviewed;         351 AA.
AC   Q9NZR1; B4DEW6;
DE   RecName: Full=Tropomodulin-2;
DE   AltName: Full=Neuronal tropomodulin;
DE            Short=N-Tmod;
GN   Name=TMOD2; Synonyms=NTMOD;
DR   GO; GO:0005523; F:tropomyosin binding; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; IEA:Ensembl.
DR   GO; GO:0045745; P:positive regulation of G-protein coupled receptor protein signaling pathway; IEA:Ensembl.
//
ID   TMOD3_HUMAN             Reviewed;         352 AA.
AC   Q9NYL9; B2R6G7; Q9NT43; Q9NZR0;
DE   RecName: Full=Tropomodulin-3;
DE   AltName: Full=Ubiquitous tropomodulin;
DE            Short=U-Tmod;
GN   Name=TMOD3;
DR   GO; GO:0005523; F:tropomyosin binding; TAS:ProtInc.
//
ID   TMOD4_HUMAN             Reviewed;         345 AA.
AC   Q9NZQ9; Q5JR83; Q8WVL3; Q9UKH2;
DE   RecName: Full=Tropomodulin-4;
DE   AltName: Full=Skeletal muscle tropomodulin;
DE            Short=Sk-Tmod;
GN   Name=TMOD4;
DR   GO; GO:0005523; F:tropomyosin binding; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
//
ID   TMPPE_HUMAN             Reviewed;         453 AA.
AC   Q6ZT21; B2RNG5; Q6ZRG1;
DE   RecName: Full=Transmembrane protein with metallophosphoesterase domain;
DE            EC=3.1.-.-;
GN   Name=TMPPE;
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   TMPS2_HUMAN             Reviewed;         492 AA.
AC   O15393; A8K6Z8; B2R8E5; B7Z459; D3DSJ2; F8WES1; Q6GTK7; Q9BXX1;
DE   RecName: Full=Transmembrane protease serine 2;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease 10;
DE   Contains:
DE     RecName: Full=Transmembrane protease serine 2 non-catalytic chain;
DE   Contains:
DE     RecName: Full=Transmembrane protease serine 2 catalytic chain;
DE   Flags: Precursor;
GN   Name=TMPRSS2; Synonyms=PRSS10;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0046598; P:positive regulation of viral entry into host cell; IDA:UniProtKB.
DR   GO; GO:0016540; P:protein autoprocessing; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   TMPS3_HUMAN             Reviewed;         454 AA.
AC   P57727; D3DSJ6; Q5USC7; Q6ZMC3;
DE   RecName: Full=Transmembrane protease serine 3;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease TADG-12;
DE   AltName: Full=Tumor-associated differentially-expressed gene 12 protein;
GN   Name=TMPRSS3; Synonyms=ECHOS1, TADG12; ORFNames=UNQ323/PRO382;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0017080; F:sodium channel regulator activity; IDA:MGI.
DR   GO; GO:0006883; P:cellular sodium ion homeostasis; IDA:MGI.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   TMPS4_HUMAN             Reviewed;         437 AA.
AC   Q9NRS4; A8MU84; B0YJB0; B7Z8C5; E7ERX8; Q5XKQ6; Q6UX37; Q9NZA5;
DE   RecName: Full=Transmembrane protease serine 4;
DE            EC=3.4.21.-;
DE   AltName: Full=Channel-activating protease 2;
DE            Short=CAPH2;
DE   AltName: Full=Membrane-type serine protease 2;
DE            Short=MT-SP2;
GN   Name=TMPRSS4; Synonyms=TMPRSS3; ORFNames=UNQ776/PRO1570;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
//
ID   TMPS5_HUMAN             Reviewed;         457 AA.
AC   Q9H3S3;
DE   RecName: Full=Transmembrane protease serine 5;
DE            EC=3.4.21.-;
DE   AltName: Full=Spinesin;
GN   Name=TMPRSS5;
DR   GO; GO:0008233; F:peptidase activity; IMP:UniProtKB.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
//
ID   TMPS6_HUMAN             Reviewed;         811 AA.
AC   Q8IU80; B0QYB4; B0QYB7; B0QYB8; Q5TI06; Q6ICC2; Q6UXD8; Q8IUE2;
AC   Q8IXV8;
DE   RecName: Full=Transmembrane protease serine 6;
DE            EC=3.4.21.-;
DE   AltName: Full=Matriptase-2;
GN   Name=TMPRSS6; ORFNames=UNQ354/PRO618;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; NAS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; NAS:UniProtKB.
DR   GO; GO:0042730; P:fibrinolysis; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0055072; P:iron ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   TMPS7_HUMAN             Reviewed;         843 AA.
AC   Q7RTY8; C9J8P7; E9PAS3; Q17RH4;
DE   RecName: Full=Transmembrane protease serine 7;
DE            EC=3.4.21.-;
DE   AltName: Full=Matriptase-3;
GN   Name=TMPRSS7;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; ISS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; ISS:UniProtKB.
//
ID   TMPS9_HUMAN             Reviewed;        1059 AA.
AC   Q7Z410; Q6ZND6; Q7Z411;
DE   RecName: Full=Transmembrane protease serine 9;
DE            EC=3.4.21.-;
DE   AltName: Full=Polyserase-I;
DE   AltName: Full=Polyserine protease 1;
DE            Short=Polyserase-1;
DE   Contains:
DE     RecName: Full=Serase-1;
DE   Contains:
DE     RecName: Full=Serase-2;
DE   Contains:
DE     RecName: Full=Serase-3;
GN   Name=TMPRSS9;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   TMPSC_HUMAN             Reviewed;         348 AA.
AC   Q86WS5; B9ZVX2;
DE   RecName: Full=Transmembrane protease serine 12;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=TMPRSS12;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
//
ID   TMPSD_HUMAN             Reviewed;         586 AA.
AC   Q9BYE2; B4DTM9; E9PIJ5; F8WAJ3; Q86YM4; Q96JY8; Q9BYE1;
DE   RecName: Full=Transmembrane protease serine 13;
DE            EC=3.4.21.-;
DE   AltName: Full=Membrane-type mosaic serine protease;
DE            Short=Mosaic serine protease;
GN   Name=TMPRSS13; Synonyms=MSP, TMPRSS11;
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
//
ID   TMTC1_HUMAN             Reviewed;         882 AA.
AC   Q8IUR5; D0EP37; F5H8B5; Q6PIU4; Q6ZSM5; Q96N52; Q9BXM2;
DE   RecName: Full=Transmembrane and TPR repeat-containing protein 1;
GN   Name=TMTC1; ORFNames=ARG99;
//
ID   TMTC2_HUMAN             Reviewed;         836 AA.
AC   Q8N394; B2RCU7; Q8N2K8;
DE   RecName: Full=Transmembrane and TPR repeat-containing protein 2;
GN   Name=TMTC2;
//
ID   TMTC3_HUMAN             Reviewed;         915 AA.
AC   Q6ZXV5; Q5CZ86; Q5H9T6; Q68DQ6; Q68DX0; Q7Z332; Q8NC50;
DE   RecName: Full=Transmembrane and TPR repeat-containing protein 3;
DE   AltName: Full=Protein SMILE;
GN   Name=TMTC3;
DR   GO; GO:0060447; P:bud outgrowth involved in lung branching; IEA:Ensembl.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
//
ID   TMTC4_HUMAN             Reviewed;         741 AA.
AC   Q5T4D3; A6NLI7; B7Z666; Q5T4D4; Q5T4D5; Q5T4D6; Q8WV63; Q96SU8;
DE   RecName: Full=Transmembrane and TPR repeat-containing protein 4;
GN   Name=TMTC4;
//
ID   TMUB1_HUMAN             Reviewed;         246 AA.
AC   Q9BVT8; D3DX06; Q53AQ2;
DE   RecName: Full=Transmembrane and ubiquitin-like domain-containing protein 1;
DE   AltName: Full=Dendritic cell-derived ubiquitin-like protein;
DE            Short=DULP;
DE   AltName: Full=Hepatocyte odd protein shuttling protein;
DE   AltName: Full=Ubiquitin-like protein SB144;
GN   Name=TMUB1; Synonyms=C7orf21, DULP, HOPS;
GN   ORFNames=SB144, UNQ763/PRO1555;
//
ID   TMUB2_HUMAN             Reviewed;         321 AA.
AC   Q71RG4; B3KU81; Q8NDI2; Q9BPZ5; Q9HAG3;
DE   RecName: Full=Transmembrane and ubiquitin-like domain-containing protein 2;
GN   Name=TMUB2; ORFNames=FP2653, UNQ1897/PRO4343;
//
ID   TMX1_HUMAN              Reviewed;         280 AA.
AC   Q9H3N1; B2R7A4; Q8N487; Q8NBN5; Q9Y4T6;
DE   RecName: Full=Thioredoxin-related transmembrane protein 1;
DE   AltName: Full=Thioredoxin domain-containing protein 1;
DE   AltName: Full=Transmembrane Trx-related protein;
DE   Flags: Precursor;
GN   Name=TMX1; Synonyms=TMX, TXNDC, TXNDC1;
GN   ORFNames=PSEC0085, UNQ235/PRO268;
DR   GO; GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:UniProtKB.
//
ID   TMX2_HUMAN              Reviewed;         296 AA.
AC   Q9Y320; B7Z4R4; Q53G73; Q561W0; Q5J7Q7; Q8NBP9; Q9H3L1;
DE   RecName: Full=Thioredoxin-related transmembrane protein 2;
DE   AltName: Full=Cell proliferation-inducing gene 26 protein;
DE   AltName: Full=Thioredoxin domain-containing protein 14;
DE   Flags: Precursor;
GN   Name=TMX2; Synonyms=TXNDC14;
GN   ORFNames=CGI-31, My009, PIG26, PSEC0045, UNQ237/PRO270;
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   TMX3_HUMAN              Reviewed;         454 AA.
AC   Q96JJ7; B3KV75; Q52LT7; Q8N5J0; Q9NWJ9;
DE   RecName: Full=Protein disulfide-isomerase TMX3;
DE            EC=5.3.4.1;
DE   AltName: Full=Thioredoxin domain-containing protein 10;
DE   AltName: Full=Thioredoxin-related transmembrane protein 3;
DE   Flags: Precursor;
GN   Name=TMX3; Synonyms=KIAA1830, TXNDC10;
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   TMX4_HUMAN              Reviewed;         349 AA.
AC   Q9H1E5; Q8N4P7; Q8NCC1; Q9UJA1; Q9ULQ8;
DE   RecName: Full=Thioredoxin-related transmembrane protein 4;
DE   AltName: Full=Thioredoxin domain-containing protein 13;
DE   Flags: Precursor;
GN   Name=TMX4; Synonyms=KIAA1162, TXNDC13;
GN   ORFNames=PSEC0095, UNQ475/PRO938;
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   TN13B_HUMAN             Reviewed;         285 AA.
AC   Q9Y275; E0ADT7; Q6FHD6; Q7Z5J2;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 13B;
DE   AltName: Full=B lymphocyte stimulator;
DE            Short=BLyS;
DE   AltName: Full=B-cell-activating factor;
DE   AltName: Full=BAFF;
DE   AltName: Full=Dendritic cell-derived TNF-like molecule;
DE   AltName: Full=TNF- and APOL-related leukocyte expressed ligand 1;
DE            Short=TALL-1;
DE   AltName: CD_antigen=CD257;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 13b, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 13b, soluble form;
GN   Name=TNFSF13B; Synonyms=BAFF, BLYS, TALL1, TNFSF20, ZTNF4;
GN   ORFNames=UNQ401/PRO738;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0031296; P:B cell costimulation; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0048305; P:immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0002636; P:positive regulation of germinal center formation; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
//
ID   TNAP2_HUMAN             Reviewed;         654 AA.
AC   Q03169; Q86VI0;
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 2;
DE            Short=TNF alpha-induced protein 2;
DE   AltName: Full=Primary response gene B94 protein;
GN   Name=TNFAIP2;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; IEA:InterPro.
//
ID   TNAP3_HUMAN             Reviewed;         790 AA.
AC   P21580; B2R767; E1P588; Q2HIX9; Q5VXQ7; Q9NSR6;
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 3;
DE            Short=TNF alpha-induced protein 3;
DE            EC=3.4.19.12;
DE            EC=6.3.2.-;
DE   AltName: Full=OTU domain-containing protein 7C;
DE   AltName: Full=Putative DNA-binding protein A20;
DE   AltName: Full=Zinc finger protein A20;
DE   Contains:
DE     RecName: Full=A20p50;
DE   Contains:
DE     RecName: Full=A20p37;
GN   Name=TNFAIP3; Synonyms=OTUD7C;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043621; F:protein self-association; IDA:BHF-UCL.
DR   GO; GO:0043130; F:ubiquitin binding; IPI:BHF-UCL.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0001922; P:B-1 B cell homeostasis; ISS:BHF-UCL.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; ISS:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050869; P:negative regulation of B cell activation; ISS:BHF-UCL.
DR   GO; GO:0045779; P:negative regulation of bone resorption; NAS:BHF-UCL.
DR   GO; GO:2000349; P:negative regulation of CD40 signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0002677; P:negative regulation of chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0045824; P:negative regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0032691; P:negative regulation of interleukin-1 beta production; IEA:Ensembl.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IMP:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0070429; P:negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway; IEA:Ensembl.
DR   GO; GO:0070433; P:negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway; IEA:Ensembl.
DR   GO; GO:0090291; P:negative regulation of osteoclast proliferation; NAS:BHF-UCL.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0034140; P:negative regulation of toll-like receptor 3 signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; NAS:BHF-UCL.
DR   GO; GO:0034148; P:negative regulation of toll-like receptor 5 signaling pathway; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; ISS:BHF-UCL.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:2000347; P:positive regulation of hepatocyte proliferation; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0016579; P:protein deubiquitination; TAS:BHF-UCL.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; NAS:BHF-UCL.
DR   GO; GO:0050691; P:regulation of defense response to virus by host; NAS:BHF-UCL.
DR   GO; GO:0002634; P:regulation of germinal center formation; ISS:BHF-UCL.
DR   GO; GO:0061043; P:regulation of vascular wound healing; NAS:BHF-UCL.
DR   GO; GO:0002237; P:response to molecule of bacterial origin; IDA:BHF-UCL.
DR   GO; GO:0032495; P:response to muramyl dipeptide; IEA:Ensembl.
DR   GO; GO:0072573; P:tolerance induction to lipopolysaccharide; IMP:BHF-UCL.
//
ID   TNC18_HUMAN             Reviewed;        2968 AA.
AC   O15417; A8MX41; Q96JH1; Q96K91;
DE   RecName: Full=Trinucleotide repeat-containing gene 18 protein;
DE   AltName: Full=Long CAG trinucleotide repeat-containing gene 79 protein;
GN   Name=TNRC18; Synonyms=CAGL79, KIAA1856;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
//
ID   TNF10_HUMAN             Reviewed;         281 AA.
AC   P50591; A1Y9B3;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 10;
DE   AltName: Full=Apo-2 ligand;
DE            Short=Apo-2L;
DE   AltName: Full=TNF-related apoptosis-inducing ligand;
DE            Short=Protein TRAIL;
DE   AltName: CD_antigen=CD253;
GN   Name=TNFSF10; Synonyms=APO2L, TRAIL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNF11_HUMAN             Reviewed;         317 AA.
AC   O14788; O14723; Q96Q17; Q9P2Q3;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 11;
DE   AltName: Full=Osteoclast differentiation factor;
DE            Short=ODF;
DE   AltName: Full=Osteoprotegerin ligand;
DE            Short=OPGL;
DE   AltName: Full=Receptor activator of nuclear factor kappa-B ligand;
DE            Short=RANKL;
DE   AltName: Full=TNF-related activation-induced cytokine;
DE            Short=TRANCE;
DE   AltName: CD_antigen=CD254;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 11, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 11, soluble form;
GN   Name=TNFSF11; Synonyms=OPGL, RANKL, TRANCE;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; NAS:UniProtKB.
DR   GO; GO:0032813; F:tumor necrosis factor receptor superfamily binding; IC:BHF-UCL.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0070371; P:ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0033598; P:mammary gland epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; NAS:UniProtKB.
DR   GO; GO:0002158; P:osteoclast proliferation; IEA:Ensembl.
DR   GO; GO:0045780; P:positive regulation of bone resorption; IDA:UniProtKB.
DR   GO; GO:0051466; P:positive regulation of corticotropin-releasing hormone secretion; ISS:BHF-UCL.
DR   GO; GO:0071848; P:positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0071812; P:positive regulation of fever generation by positive regulation of prostaglandin secretion; ISS:BHF-UCL.
DR   GO; GO:0034112; P:positive regulation of homotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:1902533; P:positive regulation of intracellular signal transduction; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0071847; P:TNFSF11-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:BHF-UCL.
//
ID   TNF12_HUMAN             Reviewed;         249 AA.
AC   O43508; Q8IZK7; Q8WUZ7;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 12;
DE   AltName: Full=APO3 ligand;
DE   AltName: Full=TNF-related weak inducer of apoptosis;
DE            Short=TWEAK;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 12, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 12, secreted form;
GN   Name=TNFSF12; Synonyms=APO3L, DR3LG; ORFNames=UNQ181/PRO207;
DR   GO; GO:0005125; F:cytokine activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043542; P:endothelial cell migration; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; TAS:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; TAS:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNF14_HUMAN             Reviewed;         240 AA.
AC   O43557; A8K7M2; C9J5H4; O75476; Q6FHA1; Q8WVF8; Q96LD2;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 14;
DE   AltName: Full=Herpes virus entry mediator ligand;
DE            Short=HVEM-L;
DE            Short=Herpesvirus entry mediator ligand;
DE   AltName: CD_antigen=CD258;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 14, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 14, soluble form;
GN   Name=TNFSF14; Synonyms=HVEML, LIGHT; ORFNames=UNQ391/PRO726;
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:GOC.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IEA:Ensembl.
DR   GO; GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; NAS:UniProtKB.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; NAS:UniProtKB.
DR   GO; GO:0042098; P:T cell proliferation; NAS:UniProtKB.
//
ID   TNF13_HUMAN             Reviewed;         250 AA.
AC   O75888; A8MYD5; B4DVT2; Q541E1; Q5U0G8; Q96HV6; Q9P1M8; Q9P1M9;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 13;
DE   AltName: Full=A proliferation-inducing ligand;
DE            Short=APRIL;
DE   AltName: Full=TNF- and APOL-related leukocyte expressed ligand 2;
DE            Short=TALL-2;
DE   AltName: Full=TNF-related death ligand 1;
DE            Short=TRDL-1;
DE   AltName: CD_antigen=CD256;
DE   Flags: Precursor;
GN   Name=TNFSF13; Synonyms=APRIL, TALL2, ZTNF2; ORFNames=UNQ383/PRO715;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0002426; P:immunoglobulin production in mucosal tissue; IEA:Ensembl.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0002636; P:positive regulation of germinal center formation; IEA:Ensembl.
DR   GO; GO:0048298; P:positive regulation of isotype switching to IgA isotypes; IDA:MGI.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNF15_HUMAN             Reviewed;         251 AA.
AC   O95150; Q3SX69; Q5VJK8; Q5VWH1; Q8NFE9;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 15;
DE   AltName: Full=TNF ligand-related molecule 1;
DE   AltName: Full=Vascular endothelial cell growth inhibitor;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 15, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 15, secreted form;
GN   Name=TNFSF15; Synonyms=TL1, VEGI;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:MGI.
DR   GO; GO:0042107; P:cytokine metabolic process; IDA:MGI.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   TNF18_HUMAN             Reviewed;         199 AA.
AC   Q9UNG2; A9IQG8; O95852; Q6ISV1;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 18;
DE   AltName: Full=Activation-inducible TNF-related ligand;
DE            Short=AITRL;
DE   AltName: Full=Glucocorticoid-induced TNF-related ligand;
DE            Short=hGITRL;
GN   Name=TNFSF18; Synonyms=AITRL, GITRL, TL6; ORFNames=UNQ149/PRO175;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0032813; F:tumor necrosis factor receptor superfamily binding; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0042129; P:regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0002309; P:T cell proliferation involved in immune response; ISS:UniProtKB.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:UniProtKB.
//
ID   TNF6B_HUMAN             Reviewed;         300 AA.
AC   O95407;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 6B;
DE   AltName: Full=Decoy receptor 3;
DE            Short=DcR3;
DE   AltName: Full=Decoy receptor for Fas ligand;
DE   AltName: Full=M68;
DE   Flags: Precursor;
GN   Name=TNFRSF6B; Synonyms=DCR3, TR6; ORFNames=UNQ186/PRO212;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
//
ID   TNFA_HUMAN              Reviewed;         233 AA.
AC   P01375; O43647; Q9P1Q2; Q9UIV3;
DE   RecName: Full=Tumor necrosis factor;
DE   AltName: Full=Cachectin;
DE   AltName: Full=TNF-alpha;
DE   AltName: Full=Tumor necrosis factor ligand superfamily member 2;
DE            Short=TNF-a;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor, membrane form;
DE     AltName: Full=N-terminal fragment;
DE              Short=NTF;
DE   Contains:
DE     RecName: Full=Intracellular domain 1;
DE              Short=ICD1;
DE   Contains:
DE     RecName: Full=Intracellular domain 2;
DE              Short=ICD2;
DE   Contains:
DE     RecName: Full=C-domain 1;
DE   Contains:
DE     RecName: Full=C-domain 2;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor, soluble form;
DE   Flags: Precursor;
GN   Name=TNF; Synonyms=TNFA, TNFSF2;
DR   GuidetoPHARMACOLOGY; 2635; -.
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IDA:BHF-UCL.
DR   GO; GO:0002020; F:protease binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; IDA:BHF-UCL.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:BHF-UCL.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IDA:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0001775; P:cell activation; IEA:Ensembl.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0071316; P:cellular response to nicotine; IDA:UniProtKB.
DR   GO; GO:0071407; P:cellular response to organic cyclic compound; IDA:UniProtKB.
DR   GO; GO:0002439; P:chronic inflammatory response to antigenic stimulus; IMP:BHF-UCL.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0048566; P:embryonic digestive tract development; IEP:DFLAT.
DR   GO; GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:UniProtKB.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IDA:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0007254; P:JNK cascade; IEA:Ensembl.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IDA:BHF-UCL.
DR   GO; GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000165; P:MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0097527; P:necroptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0010693; P:negative regulation of alkaline phosphatase activity; IEA:Ensembl.
DR   GO; GO:0061048; P:negative regulation of branching involved in lung morphogenesis; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0002740; P:negative regulation of cytokine secretion involved in immune response; IDA:BHF-UCL.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IDA:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; NAS:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0046325; P:negative regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0002037; P:negative regulation of L-glutamate transport; IEA:Ensembl.
DR   GO; GO:0050995; P:negative regulation of lipid catabolic process; IDA:BHF-UCL.
DR   GO; GO:0010888; P:negative regulation of lipid storage; NAS:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0043242; P:negative regulation of protein complex disassembly; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0060559; P:positive regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.
DR   GO; GO:2000343; P:positive regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.
DR   GO; GO:0002876; P:positive regulation of chronic inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0001819; P:positive regulation of cytokine production; IDA:BHF-UCL.
DR   GO; GO:0050715; P:positive regulation of cytokine secretion; IDA:BHF-UCL.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; NAS:BHF-UCL.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0031622; P:positive regulation of fever generation; ISS:BHF-UCL.
DR   GO; GO:0051798; P:positive regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0034116; P:positive regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032741; P:positive regulation of interleukin-18 production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045416; P:positive regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IDA:BHF-UCL.
DR   GO; GO:0045840; P:positive regulation of mitosis; IEA:Ensembl.
DR   GO; GO:0071677; P:positive regulation of mononuclear cell migration; NAS:BHF-UCL.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051533; P:positive regulation of NFAT protein import into nucleus; IDA:MGI.
DR   GO; GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0071803; P:positive regulation of podosome assembly; IDA:BHF-UCL.
DR   GO; GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.
DR   GO; GO:0043243; P:positive regulation of protein complex disassembly; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:2000010; P:positive regulation of protein localization to cell surface; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051222; P:positive regulation of protein transport; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0050806; P:positive regulation of synaptic transmission; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045994; P:positive regulation of translational initiation by iron; IEA:Ensembl.
DR   GO; GO:0060557; P:positive regulation of vitamin D biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0032800; P:receptor biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0060693; P:regulation of branching involved in salivary gland morphogenesis; IEA:Ensembl.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IDA:BHF-UCL.
DR   GO; GO:0051023; P:regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0050796; P:regulation of insulin secretion; IDA:BHF-UCL.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; TAS:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IDA:BHF-UCL.
DR   GO; GO:0030730; P:sequestering of triglyceride; IDA:BHF-UCL.
DR   GO; GO:0003009; P:skeletal muscle contraction; IEA:Ensembl.
DR   GO; GO:0006927; P:transformed cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:BHF-UCL.
//
ID   TNFB_HUMAN              Reviewed;         205 AA.
AC   P01374; Q8N4C3; Q9UKS8;
DE   RecName: Full=Lymphotoxin-alpha;
DE            Short=LT-alpha;
DE   AltName: Full=TNF-beta;
DE   AltName: Full=Tumor necrosis factor ligand superfamily member 1;
DE   Flags: Precursor;
GN   Name=LTA; Synonyms=TNFB, TNFSF1;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0006959; P:humoral immune response; IEA:Ensembl.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0002876; P:positive regulation of chronic inflammatory response to antigenic stimulus; IEA:Ensembl.
DR   GO; GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNFC_HUMAN              Reviewed;         244 AA.
AC   Q06643; P78370; Q52LU8; Q99761;
DE   RecName: Full=Lymphotoxin-beta;
DE            Short=LT-beta;
DE   AltName: Full=Tumor necrosis factor C;
DE            Short=TNF-C;
DE   AltName: Full=Tumor necrosis factor ligand superfamily member 3;
GN   Name=LTB; Synonyms=TNFC, TNFSF3;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0043588; P:skin development; IEA:Ensembl.
//
ID   TNFL4_HUMAN             Reviewed;         183 AA.
AC   P23510; Q5JZA5; Q9HCN9;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 4;
DE   AltName: Full=Glycoprotein Gp34;
DE   AltName: Full=OX40 ligand;
DE            Short=OX40L;
DE   AltName: Full=TAX transcriptionally-activated glycoprotein 1;
DE   AltName: CD_antigen=CD252;
GN   Name=TNFSF4; Synonyms=TXGP1;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0032813; F:tumor necrosis factor receptor superfamily binding; ISS:BHF-UCL.
DR   GO; GO:0002526; P:acute inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0035783; P:CD4-positive, alpha-beta T cell costimulation; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0035714; P:cellular response to nitrogen dioxide; IEA:Ensembl.
DR   GO; GO:0071380; P:cellular response to prostaglandin E stimulus; IDA:BHF-UCL.
DR   GO; GO:0071954; P:chemokine (C-C motif) ligand 11 production; ISS:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:Ensembl.
DR   GO; GO:0002215; P:defense response to nematode; ISS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0035709; P:memory T cell activation; ISS:BHF-UCL.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; ISS:BHF-UCL.
DR   GO; GO:0032700; P:negative regulation of interleukin-17 production; IDA:BHF-UCL.
DR   GO; GO:0045590; P:negative regulation of regulatory T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045626; P:negative regulation of T-helper 1 cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0050871; P:positive regulation of B cell activation; ISS:BHF-UCL.
DR   GO; GO:1900281; P:positive regulation of CD4-positive, alpha-beta T cell costimulation; ISS:BHF-UCL.
DR   GO; GO:0043372; P:positive regulation of CD4-positive, alpha-beta T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0002891; P:positive regulation of immunoglobulin mediated immune response; ISS:BHF-UCL.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; ISS:BHF-UCL.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.
DR   GO; GO:0032736; P:positive regulation of interleukin-13 production; ISS:BHF-UCL.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; IDA:BHF-UCL.
DR   GO; GO:2000572; P:positive regulation of interleukin-4-dependent isotype switching to IgE isotypes; ISS:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:2000568; P:positive regulation of memory T cell activation; IEA:Ensembl.
DR   GO; GO:0043382; P:positive regulation of memory T cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; ISS:BHF-UCL.
DR   GO; GO:2000570; P:positive regulation of T-helper 2 cell activation; IEA:Ensembl.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0002830; P:positive regulation of type 2 immune response; ISS:BHF-UCL.
DR   GO; GO:0002819; P:regulation of adaptive immune response; ISS:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0035713; P:response to nitrogen dioxide; ISS:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0035712; P:T-helper 2 cell activation; ISS:BHF-UCL.
//
ID   TNFL6_HUMAN             Reviewed;         281 AA.
AC   P48023; Q9BZP9;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 6;
DE   AltName: Full=Apoptosis antigen ligand;
DE            Short=APTL;
DE   AltName: Full=CD95 ligand;
DE            Short=CD95-L;
DE   AltName: Full=Fas antigen ligand;
DE            Short=Fas ligand;
DE            Short=FasL;
DE   AltName: CD_antigen=CD178;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 6, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor ligand superfamily member 6, soluble form;
DE     AltName: Full=Receptor-binding FasL ectodomain;
DE     AltName: Full=Soluble Fas ligand;
DE              Short=sFasL;
DE   Contains:
DE     RecName: Full=ADAM10-processed FasL form;
DE              Short=APL;
DE   Contains:
DE     RecName: Full=FasL intracellular domain;
DE              Short=FasL ICD;
DE     AltName: Full=SPPL2A-processed FasL form;
DE              Short=SPA;
GN   Name=FASLG; Synonyms=APT1LG1, CD95L, FASL, TNFSF6;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0030644; P:cellular chloride ion homeostasis; IEA:Ensembl.
DR   GO; GO:0048388; P:endosomal lumen acidification; IEA:Ensembl.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006925; P:inflammatory cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0070266; P:necroptotic process; IDA:BHF-UCL.
DR   GO; GO:0097527; P:necroptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0070848; P:response to growth factor; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0046666; P:retinal cell programmed cell death; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0070231; P:T cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TNFL8_HUMAN             Reviewed;         234 AA.
AC   P32971; O43404;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 8;
DE   AltName: Full=CD30 ligand;
DE            Short=CD30-L;
DE   AltName: CD_antigen=CD153;
GN   Name=TNFSF8; Synonyms=CD30L, CD30LG;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0043374; P:CD8-positive, alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNG2_HUMAN              Reviewed;         276 AA.
AC   Q6ICL3; A8MUE9; D3DX23; Q8IW05; Q8NAL0; Q8TCS0; Q96M16;
DE   RecName: Full=Transport and Golgi organization protein 2 homolog;
GN   Name=TANGO2; Synonyms=C22orf25;
//
ID   TNFL9_HUMAN             Reviewed;         254 AA.
AC   P41273; Q2M3S2;
DE   RecName: Full=Tumor necrosis factor ligand superfamily member 9;
DE   AltName: Full=4-1BB ligand;
DE            Short=4-1BBL;
GN   Name=TNFSF9;
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0042104; P:positive regulation of activated T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045585; P:positive regulation of cytotoxic T cell differentiation; IEA:Ensembl.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNG6_HUMAN              Reviewed;        1094 AA.
AC   Q9C0B7; Q569F9; Q9H9K1;
DE   RecName: Full=Transport and Golgi organization protein 6 homolog;
DE   AltName: Full=Transmembrane and coiled-coil domain-containing protein 7;
GN   Name=TANGO6; Synonyms=KIAA1746, TMCO7;
//
ID   TNI3K_HUMAN             Reviewed;         835 AA.
AC   Q59H18; Q17RN0; Q49AR1; Q6MZS9; Q9Y2V6;
DE   RecName: Full=Serine/threonine-protein kinase TNNI3K;
DE            EC=2.7.11.1;
DE   AltName: Full=Cardiac ankyrin repeat kinase;
DE   AltName: Full=Cardiac troponin I-interacting kinase;
DE   AltName: Full=TNNI3-interacting kinase;
GN   Name=TNNI3K; Synonyms=CARK;
DR   GuidetoPHARMACOLOGY; 2247; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031013; F:troponin I binding; IPI:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
//
ID   TNIK_HUMAN              Reviewed;        1360 AA.
AC   Q9UKE5; A7E2A3; A8K4U1; D3DNQ6; O60298; Q8WUY7; Q9UKD8; Q9UKD9;
AC   Q9UKE0; Q9UKE1; Q9UKE2; Q9UKE3; Q9UKE4;
DE   RecName: Full=TRAF2 and NCK-interacting protein kinase;
DE            EC=2.7.11.1;
GN   Name=TNIK; Synonyms=KIAA0551;
DR   GuidetoPHARMACOLOGY; 2244; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IBA:RefGenome.
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.
DR   GO; GO:0007256; P:activation of JNKK activity; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TNIP1_HUMAN             Reviewed;         636 AA.
AC   Q15025; B7Z699; O76008; Q6N077; Q96EL9; Q99833; Q9H1J3;
DE   RecName: Full=TNFAIP3-interacting protein 1;
DE   AltName: Full=A20-binding inhibitor of NF-kappa-B activation 1;
DE            Short=ABIN-1;
DE   AltName: Full=HIV-1 Nef-interacting protein;
DE   AltName: Full=Nef-associated factor 1;
DE            Short=Naf1;
DE   AltName: Full=Nip40-1;
DE   AltName: Full=Virion-associated nuclear shuttling protein;
DE            Short=VAN;
DE            Short=hVAN;
GN   Name=TNIP1; Synonyms=KIAA0113, NAF1;
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0009101; P:glycoprotein biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0085032; P:modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; TAS:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; TAS:ProtInc.
//
ID   TNIP2_HUMAN             Reviewed;         429 AA.
AC   Q8NFZ5; B1AKS4; B3KTY8; D3DVQ9; Q7L5L2; Q9BQR6; Q9H682;
DE   RecName: Full=TNFAIP3-interacting protein 2;
DE   AltName: Full=A20-binding inhibitor of NF-kappa-B activation 2;
DE            Short=ABIN-2;
DE   AltName: Full=Fetal liver LKB1-interacting protein;
GN   Name=TNIP2; Synonyms=ABIN2, FLIP1;
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0023035; P:CD40 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; ISS:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0050871; P:positive regulation of B cell activation; ISS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TNIP3_HUMAN             Reviewed;         325 AA.
AC   Q96KP6; A1A574; A8K2Z4; B4DVF5; B4E023; Q96PQ3; Q9H780;
DE   RecName: Full=TNFAIP3-interacting protein 3;
DE   AltName: Full=A20-binding inhibitor of NF-kappa-B activation 3;
DE            Short=ABIN-3;
DE   AltName: Full=Listeria-induced gene protein;
GN   Name=TNIP3; Synonyms=ABIN3, LIND;
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:UniProtKB.
//
ID   TNK1_HUMAN              Reviewed;         666 AA.
AC   Q13470; O95364; Q8IYI4;
DE   RecName: Full=Non-receptor tyrosine-protein kinase TNK1;
DE            EC=2.7.10.2;
DE   AltName: Full=CD38 negative kinase 1;
GN   Name=TNK1;
DR   GuidetoPHARMACOLOGY; 2245; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   TNKS1_HUMAN             Reviewed;        1327 AA.
AC   O95271; O95272; Q4G0F2;
DE   RecName: Full=Tankyrase-1;
DE            Short=TANK1;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 5;
DE            Short=ARTD5;
DE   AltName: Full=Poly [ADP-ribose] polymerase 5A;
DE   AltName: Full=TNKS-1;
DE   AltName: Full=TRF1-interacting ankyrin-related ADP-ribose polymerase;
DE   AltName: Full=Tankyrase I;
GN   Name=TNKS; Synonyms=PARP5A, PARPL, TIN1, TINF1, TNKS1;
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.
DR   GO; GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032212; P:positive regulation of telomere maintenance via telomerase; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IDA:BHF-UCL.
DR   GO; GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.
DR   GO; GO:0070212; P:protein poly-ADP-ribosylation; IDA:BHF-UCL.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032210; P:regulation of telomere maintenance via telomerase; IC:BHF-UCL.
DR   GO; GO:0051225; P:spindle assembly; TAS:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TNKS2_HUMAN             Reviewed;        1166 AA.
AC   Q9H2K2; B2RBD3; Q9H8F2; Q9HAS4;
DE   RecName: Full=Tankyrase-2;
DE            Short=TANK2;
DE            EC=2.4.2.30;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 6;
DE            Short=ARTD6;
DE   AltName: Full=Poly [ADP-ribose] polymerase 5B;
DE   AltName: Full=TNKS-2;
DE   AltName: Full=TRF1-interacting ankyrin-related ADP-ribose polymerase 2;
DE   AltName: Full=Tankyrase II;
DE   AltName: Full=Tankyrase-like protein;
DE   AltName: Full=Tankyrase-related protein;
GN   Name=TNKS2; Synonyms=PARP5B, TANK2, TNKL;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.
DR   GO; GO:0006471; P:protein ADP-ribosylation; IDA:BHF-UCL.
DR   GO; GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.
DR   GO; GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0040014; P:regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TNMD_HUMAN              Reviewed;         317 AA.
AC   Q9H2S6; Q9HBX0; Q9UJG0;
DE   RecName: Full=Tenomodulin;
DE            Short=TeM;
DE            Short=hTeM;
DE   AltName: Full=Chondromodulin-1-like protein;
DE            Short=ChM1L;
DE            Short=hChM1L;
DE   AltName: Full=Chondromodulin-I-like protein;
DE   AltName: Full=Myodulin;
DE   AltName: Full=Tendin;
GN   Name=TNMD; Synonyms=CHM1L; ORFNames=UNQ771/PRO1565;
DR   GO; GO:0071773; P:cellular response to BMP stimulus; IEA:Ensembl.
DR   GO; GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0035990; P:tendon cell differentiation; IEA:Ensembl.
//
ID   TNNC1_HUMAN             Reviewed;         161 AA.
AC   P63316; O14800; P02590; P04463;
DE   RecName: Full=Troponin C, slow skeletal and cardiac muscles;
DE            Short=TN-C;
GN   Name=TNNC1; Synonyms=TNNC;
DR   GO; GO:0051015; F:actin filament binding; ISS:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IDA:BHF-UCL.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0031013; F:troponin I binding; IPI:UniProtKB.
DR   GO; GO:0031014; F:troponin T binding; IPI:UniProtKB.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0002086; P:diaphragm contraction; IEA:Ensembl.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0043462; P:regulation of ATPase activity; ISS:BHF-UCL.
DR   GO; GO:0006937; P:regulation of muscle contraction; TAS:UniProtKB.
DR   GO; GO:0032972; P:regulation of muscle filament sliding speed; ISS:BHF-UCL.
DR   GO; GO:0010038; P:response to metal ion; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   TNNC2_HUMAN             Reviewed;         160 AA.
AC   P02585; Q6FH92;
DE   RecName: Full=Troponin C, skeletal muscle;
GN   Name=TNNC2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.
DR   GO; GO:0003009; P:skeletal muscle contraction; IDA:UniProtKB.
//
ID   TNNI1_HUMAN             Reviewed;         187 AA.
AC   P19237; A6NEH3; A8MSJ0; Q659A5; Q6FGS7; Q6FGW1; Q6ICU2; Q86T57;
AC   Q96DT9;
DE   RecName: Full=Troponin I, slow skeletal muscle;
DE   AltName: Full=Troponin I, slow-twitch isoform;
GN   Name=TNNI1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; NAS:UniProtKB.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
//
ID   TNNI2_HUMAN             Reviewed;         182 AA.
AC   P48788; A6NIV8; A6NJU5;
DE   RecName: Full=Troponin I, fast skeletal muscle;
DE   AltName: Full=Troponin I, fast-twitch isoform;
GN   Name=TNNI2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031014; F:troponin T binding; IPI:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0003009; P:skeletal muscle contraction; IDA:UniProtKB.
//
ID   TNNI3_HUMAN             Reviewed;         210 AA.
AC   P19429;
DE   RecName: Full=Troponin I, cardiac muscle;
DE   AltName: Full=Cardiac troponin I;
GN   Name=TNNI3; Synonyms=TNNC1;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0019855; F:calcium channel inhibitor activity; IPI:UniProtKB.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0030172; F:troponin C binding; IPI:UniProtKB.
DR   GO; GO:0031014; F:troponin T binding; IPI:UniProtKB.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:UniProtKB.
DR   GO; GO:0060047; P:heart contraction; IMP:UniProtKB.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; IDA:UniProtKB.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; IEA:Ensembl.
DR   GO; GO:0001980; P:regulation of systemic arterial blood pressure by ischemic conditions; ISS:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   TNNT1_HUMAN             Reviewed;         278 AA.
AC   P13805; O95472; Q16061; Q5U0E1;
DE   RecName: Full=Troponin T, slow skeletal muscle;
DE            Short=TnTs;
DE   AltName: Full=Slow skeletal muscle troponin T;
DE            Short=sTnT;
GN   Name=TNNT1; Synonyms=TNT;
DR   GO; GO:0005523; F:tropomyosin binding; IMP:UniProtKB.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0045932; P:negative regulation of muscle contraction; IDA:UniProtKB.
DR   GO; GO:0003009; P:skeletal muscle contraction; IMP:UniProtKB.
DR   GO; GO:0031444; P:slow-twitch skeletal muscle fiber contraction; IEA:Ensembl.
//
ID   TNNT2_HUMAN             Reviewed;         298 AA.
AC   P45379; A2TDB9; A8K3K6; O60214; Q99596; Q99597; Q9BUF6; Q9UM96;
DE   RecName: Full=Troponin T, cardiac muscle;
DE            Short=TnTc;
DE   AltName: Full=Cardiac muscle troponin T;
DE            Short=cTnT;
GN   Name=TNNT2;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl.
DR   GO; GO:0005523; F:tropomyosin binding; IDA:UniProtKB.
DR   GO; GO:0030172; F:troponin C binding; IPI:UniProtKB.
DR   GO; GO:0031013; F:troponin I binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0030049; P:muscle filament sliding; IDA:UniProtKB.
DR   GO; GO:0032780; P:negative regulation of ATPase activity; IDA:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.
DR   GO; GO:0008016; P:regulation of heart contraction; IMP:UniProtKB.
DR   GO; GO:0006937; P:regulation of muscle contraction; IEA:InterPro.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
//
ID   TNNT3_HUMAN             Reviewed;         269 AA.
AC   P45378; A8MQ76; A8MSW1; B3KPX3; B7WP64; B7ZL26; B7ZVV9; Q12975;
AC   Q12976; Q12977; Q12978; Q17RG9; Q6FH29; Q6N056; Q86TH6;
DE   RecName: Full=Troponin T, fast skeletal muscle;
DE            Short=TnTf;
DE   AltName: Full=Beta-TnTF;
DE   AltName: Full=Fast skeletal muscle troponin T;
DE            Short=fTnT;
GN   Name=TNNT3;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IDA:UniProtKB.
DR   GO; GO:0005523; F:tropomyosin binding; IMP:UniProtKB.
DR   GO; GO:0030172; F:troponin C binding; IPI:UniProtKB.
DR   GO; GO:0031013; F:troponin I binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0043462; P:regulation of ATPase activity; IDA:UniProtKB.
DR   GO; GO:0006942; P:regulation of striated muscle contraction; IDA:UniProtKB.
DR   GO; GO:0003009; P:skeletal muscle contraction; IDA:UniProtKB.
//
ID   TNPO1_HUMAN             Reviewed;         898 AA.
AC   Q92973; B4DVC6; Q92957; Q92975;
DE   RecName: Full=Transportin-1;
DE   AltName: Full=Importin beta-2;
DE   AltName: Full=Karyopherin beta-2;
DE   AltName: Full=M9 region interaction protein;
DE            Short=MIP;
GN   Name=TNPO1; Synonyms=KPNB2, MIP1, TRN;
DR   GO; GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TNPO2_HUMAN             Reviewed;         897 AA.
AC   O14787; O14655; Q6IN77;
DE   RecName: Full=Transportin-2;
DE   AltName: Full=Karyopherin beta-2b;
GN   Name=TNPO2;
DR   GO; GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   TNPO3_HUMAN             Reviewed;         923 AA.
AC   Q9Y5L0; A4D1K9; C9IZM0; Q6NUM1; Q96G71; Q96GU9; Q9Y3R2;
DE   RecName: Full=Transportin-3;
DE   AltName: Full=Importin-12;
DE            Short=Imp12;
DE   AltName: Full=Transportin-SR;
DE            Short=TRN-SR;
GN   Name=TNPO3; Synonyms=IPO12;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0035048; P:splicing factor protein import into nucleus; IDA:UniProtKB.
//
ID   TNR11_HUMAN             Reviewed;         616 AA.
AC   Q9Y6Q6; I4EC36; I4EC38; I4EC39; I7JE63; N0GVH0; Q59EP9;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 11A;
DE   AltName: Full=Osteoclast differentiation factor receptor;
DE            Short=ODFR;
DE   AltName: Full=Receptor activator of NF-KB;
DE   AltName: CD_antigen=CD265;
DE   Flags: Precursor;
GN   Name=TNFRSF11A; Synonyms=RANK;
DR   GuidetoPHARMACOLOGY; 1881; -.
DR   GO; GO:0019955; F:cytokine binding; IPI:BHF-UCL.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IDA:BHF-UCL.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; ISS:BHF-UCL.
DR   GO; GO:0002250; P:adaptive immune response; IMP:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0060086; P:circadian temperature homeostasis; ISS:BHF-UCL.
DR   GO; GO:0048535; P:lymph node development; IEA:Ensembl.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0002548; P:monocyte chemotaxis; NAS:BHF-UCL.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0030316; P:osteoclast differentiation; IMP:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0071848; P:positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling; IMP:BHF-UCL.
DR   GO; GO:0071812; P:positive regulation of fever generation by positive regulation of prostaglandin secretion; ISS:BHF-UCL.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0034097; P:response to cytokine; IMP:BHF-UCL.
DR   GO; GO:0070555; P:response to interleukin-1; ISS:BHF-UCL.
DR   GO; GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.
DR   GO; GO:0009314; P:response to radiation; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0071847; P:TNFSF11-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; ISS:BHF-UCL.
//
ID   TNR12_HUMAN             Reviewed;         129 AA.
AC   Q9NP84; D3DUA6; Q9HCS0;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 12A;
DE   AltName: Full=Fibroblast growth factor-inducible immediate-early response protein 14;
DE            Short=FGF-inducible 14;
DE   AltName: Full=Tweak-receptor;
DE            Short=TweakR;
DE   AltName: CD_antigen=CD266;
DE   Flags: Precursor;
GN   Name=TNFRSF12A; Synonyms=FN14;
DR   GuidetoPHARMACOLOGY; 1884; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProt.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006931; P:substrate-dependent cell migration, cell attachment to substrate; IEA:Ensembl.
//
ID   TNR14_HUMAN             Reviewed;         283 AA.
AC   Q92956; B3KW30; B9DI89; Q6IB95; Q8N634; Q8WXR1; Q96J31; Q9UM65;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 14;
DE   AltName: Full=Herpes virus entry mediator A;
DE            Short=Herpesvirus entry mediator A;
DE            Short=HveA;
DE   AltName: Full=Tumor necrosis factor receptor-like 2;
DE            Short=TR2;
DE   AltName: CD_antigen=CD270;
DE   Flags: Precursor;
GN   Name=TNFRSF14; Synonyms=HVEA, HVEM; ORFNames=UNQ329/PRO509;
DR   GuidetoPHARMACOLOGY; 1887; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0050829; P:defense response to Gram-negative bacterium; IEA:Ensembl.
DR   GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0002741; P:positive regulation of cytokine secretion involved in immune response; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IEA:Ensembl.
DR   GO; GO:2000406; P:positive regulation of T cell migration; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TNR16_HUMAN             Reviewed;         427 AA.
AC   P08138; B2R961;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 16;
DE   AltName: Full=Gp80-LNGFR;
DE   AltName: Full=Low affinity neurotrophin receptor p75NTR;
DE   AltName: Full=Low-affinity nerve growth factor receptor;
DE            Short=NGF receptor;
DE   AltName: Full=p75 ICD;
DE   AltName: CD_antigen=CD271;
DE   Flags: Precursor;
GN   Name=NGFR; Synonyms=TNFRSF16;
DR   GuidetoPHARMACOLOGY; 1888; -.
DR   GO; GO:0005035; F:death receptor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0016048; P:detection of temperature stimulus; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0050771; P:negative regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:Reactome.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051799; P:negative regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0021675; P:nerve development; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0050772; P:positive regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0042488; P:positive regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; TAS:Reactome.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:2001273; P:regulation of glucose import in response to insulin stimulus; ISS:UniProtKB.
//
ID   TNR17_HUMAN             Reviewed;         184 AA.
AC   Q02223; Q2TQ40;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 17;
DE   AltName: Full=B-cell maturation protein;
DE   AltName: CD_antigen=CD269;
GN   Name=TNFRSF17; Synonyms=BCM, BCMA;
DR   GuidetoPHARMACOLOGY; 1889; -.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNR19_HUMAN             Reviewed;         423 AA.
AC   Q9NS68; A8KA09; A8KA26; B1AM40; B1AM41; B4E2I6; Q9BXZ9; Q9BY00;
AC   Q9NZV2;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 19;
DE   AltName: Full=TRADE;
DE   AltName: Full=Toxicity and JNK inducer;
DE   Flags: Precursor;
GN   Name=TNFRSF19; Synonyms=TAJ, TROY; ORFNames=UNQ1888/PRO4333;
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0007254; P:JNK cascade; NAS:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; NAS:GOC.
//
ID   TNR18_HUMAN             Reviewed;         241 AA.
AC   Q9Y5U5; B1AME1; O95851; Q5U0I4; Q9NYJ9;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 18;
DE   AltName: Full=Activation-inducible TNFR family receptor;
DE   AltName: Full=Glucocorticoid-induced TNFR-related protein;
DE   AltName: CD_antigen=CD357;
DE   Flags: Precursor;
GN   Name=TNFRSF18; Synonyms=AITR, GITR; ORFNames=UNQ319/PRO364;
DR   GuidetoPHARMACOLOGY; 1890; -.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:GOC.
//
ID   TNR1A_HUMAN             Reviewed;         455 AA.
AC   P19438; A8K4X3; B2RDE4; B3KPQ1; B4DQB7; B4E309; B5M0B5; D3DUR1;
AC   Q9UCA4;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 1A;
DE   AltName: Full=Tumor necrosis factor receptor 1;
DE            Short=TNF-R1;
DE   AltName: Full=Tumor necrosis factor receptor type I;
DE            Short=TNF-RI;
DE            Short=TNFR-I;
DE   AltName: Full=p55;
DE   AltName: Full=p60;
DE   AltName: CD_antigen=CD120a;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor receptor superfamily member 1A, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor-binding protein 1;
DE              Short=TBPI;
DE   Flags: Precursor;
GN   Name=TNFRSF1A; Synonyms=TNFAR, TNFR1;
DR   GuidetoPHARMACOLOGY; 1870; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; TAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; ISS:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:BHF-UCL.
DR   GO; GO:0006693; P:prostaglandin metabolic process; IEA:InterPro.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0043279; P:response to alkaloid; IEA:Ensembl.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0033013; P:tetrapyrrole metabolic process; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TNR1B_HUMAN             Reviewed;         461 AA.
AC   P20333; B1AJZ3; Q16042; Q6YI29; Q9UIH1;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 1B;
DE   AltName: Full=Tumor necrosis factor receptor 2;
DE            Short=TNF-R2;
DE   AltName: Full=Tumor necrosis factor receptor type II;
DE            Short=TNF-RII;
DE            Short=TNFR-II;
DE   AltName: Full=p75;
DE   AltName: Full=p80 TNF-alpha receptor;
DE   AltName: CD_antigen=CD120b;
DE   AltName: INN=Etanercept;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor receptor superfamily member 1b, membrane form;
DE   Contains:
DE     RecName: Full=Tumor necrosis factor-binding protein 2;
DE     AltName: Full=TBP-2;
DE     AltName: Full=TBPII;
DE   Flags: Precursor;
GN   Name=TNFRSF1B; Synonyms=TNFBR, TNFR2;
DR   GuidetoPHARMACOLOGY; 1871; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IMP:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.
DR   GO; GO:0050779; P:RNA destabilization; IEA:Ensembl.
//
ID   TNR21_HUMAN             Reviewed;         655 AA.
AC   O75509; B2RDI9; Q0D2P5; Q96D86;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 21;
DE   AltName: Full=Death receptor 6;
DE   AltName: CD_antigen=CD358;
DE   Flags: Precursor;
GN   Name=TNFRSF21; Synonyms=DR6; ORFNames=UNQ437/PRO868;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0002250; P:adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IMP:UniProtKB.
DR   GO; GO:0001783; P:B cell apoptotic process; ISS:UniProtKB.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; ISS:UniProtKB.
DR   GO; GO:0042552; P:myelination; ISS:UniProtKB.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; ISS:UniProtKB.
DR   GO; GO:2001180; P:negative regulation of interleukin-10 secretion; ISS:UniProtKB.
DR   GO; GO:2000666; P:negative regulation of interleukin-13 secretion; ISS:UniProtKB.
DR   GO; GO:2000663; P:negative regulation of interleukin-5 secretion; ISS:UniProtKB.
DR   GO; GO:0031642; P:negative regulation of myelination; IMP:UniProtKB.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0097252; P:oligodendrocyte apoptotic process; ISS:UniProtKB.
DR   GO; GO:0048713; P:regulation of oligodendrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
//
ID   TNR25_HUMAN             Reviewed;         417 AA.
AC   Q93038; B1ALX2; B1ALX3; B7ZLL7; O00275; O00276; O00277; O00278;
AC   O00279; O00280; O14865; O14866; P78507; P78515; Q17RU4; Q92983;
AC   Q93036; Q93037; Q99722; Q99830; Q99831; Q9BY86; Q9UME0; Q9UME1;
AC   Q9UME5;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 25;
DE   AltName: Full=Apo-3;
DE   AltName: Full=Apoptosis-inducing receptor AIR;
DE   AltName: Full=Apoptosis-mediating receptor DR3;
DE   AltName: Full=Apoptosis-mediating receptor TRAMP;
DE   AltName: Full=Death receptor 3;
DE   AltName: Full=Lymphocyte-associated receptor of death;
DE            Short=LARD;
DE   AltName: Full=Protein WSL;
DE   AltName: Full=Protein WSL-1;
DE   Flags: Precursor;
GN   Name=TNFRSF25; Synonyms=APO3, DDR3, DR3, TNFRSF12, WSL, WSL1;
GN   ORFNames=UNQ455/PRO779;
DR   GuidetoPHARMACOLOGY; 1883; -.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:GOC.
//
ID   TNR27_HUMAN             Reviewed;         297 AA.
AC   Q9HAV5; Q5VYX9; Q5VYY0; Q6UWM2; Q8IZA6;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 27;
DE   AltName: Full=X-linked ectodysplasin-A2 receptor;
DE            Short=EDA-A2 receptor;
GN   Name=EDA2R; Synonyms=TNFRSF27, XEDAR;
GN   ORFNames=UNQ2448/PRO5727/PRO34080;
DR   GuidetoPHARMACOLOGY; 1896; -.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0004872; F:receptor activity; IDA:HGNC.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0009790; P:embryo development; NAS:HGNC.
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:HGNC.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:HGNC.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; NAS:GOC.
//
ID   TNR3_HUMAN              Reviewed;         435 AA.
AC   P36941; B7Z1D2; D3DUR2; F5GXE7;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 3;
DE   AltName: Full=Lymphotoxin-beta receptor;
DE   AltName: Full=Tumor necrosis factor C receptor;
DE   AltName: Full=Tumor necrosis factor receptor 2-related protein;
DE   AltName: Full=Tumor necrosis factor receptor type III;
DE            Short=TNF-RIII;
DE            Short=TNFR-III;
DE   Flags: Precursor;
GN   Name=LTBR; Synonyms=D12S370, TNFCR, TNFR3, TNFRSF3;
DR   GuidetoPHARMACOLOGY; 1872; -.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TNR4_HUMAN              Reviewed;         277 AA.
AC   P43489; Q13663; Q2M312; Q5T7M0;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 4;
DE   AltName: Full=ACT35 antigen;
DE   AltName: Full=OX40L receptor;
DE   AltName: Full=TAX transcriptionally-activated glycoprotein 1 receptor;
DE   AltName: CD_antigen=CD134;
DE   Flags: Precursor;
GN   Name=TNFRSF4; Synonyms=TXGP1L;
DR   GuidetoPHARMACOLOGY; 1873; -.
DR   GO; GO:0005031; F:tumor necrosis factor-activated receptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0050710; P:negative regulation of cytokine secretion; IEA:Ensembl.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0051024; P:positive regulation of immunoglobulin secretion; ISS:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0042098; P:T cell proliferation; ISS:BHF-UCL.
//
ID   TNR5_HUMAN              Reviewed;         277 AA.
AC   P25942; E1P5S9; Q53GN5; Q5JY15; Q5U007; Q7M4Q8; Q86YK5; Q9BYU0;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 5;
DE   AltName: Full=B-cell surface antigen CD40;
DE   AltName: Full=Bp50;
DE   AltName: Full=CD40L receptor;
DE   AltName: Full=CDw40;
DE   AltName: CD_antigen=CD40;
DE   Flags: Precursor;
GN   Name=CD40; Synonyms=TNFRSF5;
DR   GuidetoPHARMACOLOGY; 1874; -.
DR   GO; GO:0003823; F:antigen binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0042100; P:B cell proliferation; NAS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:BHF-UCL.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; NAS:UniProtKB.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0043089; P:positive regulation of Cdc42 GTPase activity; IMP:BHF-UCL.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0032735; P:positive regulation of interleukin-12 production; IEA:Ensembl.
DR   GO; GO:0048304; P:positive regulation of isotype switching to IgG isotypes; IEA:Ensembl.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IMP:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; IMP:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0051023; P:regulation of immunoglobulin secretion; IEA:Ensembl.
//
ID   TNR6A_HUMAN             Reviewed;        1962 AA.
AC   Q8NDV7; C9JAR8; O15408; Q658L5; Q6NVB5; Q8NEZ0; Q8TBT8; Q8TCR0;
AC   Q9NV59; Q9P268;
DE   RecName: Full=Trinucleotide repeat-containing gene 6A protein;
DE   AltName: Full=CAG repeat protein 26;
DE   AltName: Full=EMSY interactor protein;
DE   AltName: Full=GW182 autoantigen;
DE            Short=Protein GW1;
DE   AltName: Full=Glycine-tryptophan protein of 182 kDa;
GN   Name=TNRC6A; Synonyms=CAGH26, KIAA1460, TNRC6;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
//
ID   TNR6B_HUMAN             Reviewed;        1833 AA.
AC   Q9UPQ9; B0QY73; B0QY78; B4DGC0; Q5TH52; Q8TBX2;
DE   RecName: Full=Trinucleotide repeat-containing gene 6B protein;
GN   Name=TNRC6B; Synonyms=KIAA1093;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IMP:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
//
ID   TNR6C_HUMAN             Reviewed;        1690 AA.
AC   Q9HCJ0; G3XAB8; Q86UE5; Q8N3D8; Q96MU9;
DE   RecName: Full=Trinucleotide repeat-containing gene 6C protein;
GN   Name=TNRC6C; Synonyms=KIAA1582;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; TAS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:UniProtKB.
//
ID   TNR6_HUMAN              Reviewed;         335 AA.
AC   P25445; A9UJX4; B6VNV4; Q14292; Q14293; Q14294; Q14295; Q16652;
AC   Q5T9P1; Q5T9P2; Q5T9P3; Q6SSE9;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 6;
DE   AltName: Full=Apo-1 antigen;
DE   AltName: Full=Apoptosis-mediating surface antigen FAS;
DE   AltName: Full=FASLG receptor;
DE   AltName: CD_antigen=CD95;
DE   Flags: Precursor;
GN   Name=FAS; Synonyms=APT1, FAS1, TNFRSF6;
DR   GuidetoPHARMACOLOGY; 1875; -.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0006924; P:activation-induced cell death of T cells; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0019724; P:B cell mediated immunity; IEA:Ensembl.
DR   GO; GO:0071455; P:cellular response to hyperoxia; IMP:UniProtKB.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0002377; P:immunoglobulin production; IEA:Ensembl.
DR   GO; GO:0006925; P:inflammatory cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0097049; P:motor neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0097527; P:necroptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0050869; P:negative regulation of B cell activation; IEA:Ensembl.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0032464; P:positive regulation of protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0045619; P:regulation of lymphocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045637; P:regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0003014; P:renal system process; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0048536; P:spleen development; IEA:Ensembl.
DR   GO; GO:0006927; P:transformed cell apoptotic process; IEA:Ensembl.
//
ID   TNR8_HUMAN              Reviewed;         595 AA.
AC   P28908; B1AN79; Q6P4D9;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 8;
DE   AltName: Full=CD30L receptor;
DE   AltName: Full=Ki-1 antigen;
DE   AltName: Full=Lymphocyte activation antigen CD30;
DE   AltName: CD_antigen=CD30;
DE   Flags: Precursor;
GN   Name=TNFRSF8; Synonyms=CD30, D1S166E;
DR   GuidetoPHARMACOLOGY; 1877; -.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045556; P:positive regulation of TRAIL biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TNR9_HUMAN              Reviewed;         255 AA.
AC   Q07011;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 9;
DE   AltName: Full=4-1BB ligand receptor;
DE   AltName: Full=CDw137;
DE   AltName: Full=T-cell antigen 4-1BB homolog;
DE   AltName: Full=T-cell antigen ILA;
DE   AltName: CD_antigen=CD137;
DE   Flags: Precursor;
GN   Name=TNFRSF9; Synonyms=CD137, ILA;
DR   GuidetoPHARMACOLOGY; 1878; -.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:2001180; P:negative regulation of interleukin-10 secretion; IEA:Ensembl.
DR   GO; GO:2001183; P:negative regulation of interleukin-12 secretion; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:Ensembl.
//
ID   TNT_HUMAN               Reviewed;         217 AA.
AC   Q7Z2V1; B9EGC2; Q8NEF0;
DE   RecName: Full=Protein TNT;
GN   Name=C16orf82;
//
ID   TO20L_HUMAN             Reviewed;         152 AA.
AC   Q6UXN7; B2RPR0;
DE   RecName: Full=TOMM20-like protein 1;
GN   Name=TOMM20L; ORFNames=UNQ9438/PRO34772;
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
//
ID   TOB1_HUMAN              Reviewed;         345 AA.
AC   P50616; B2R9T0; D3DTY3; Q4KMQ0;
DE   RecName: Full=Protein Tob1;
DE   AltName: Full=Transducer of erbB-2 1;
GN   Name=TOB1; Synonyms=TOB, TROB1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IDA:UniProtKB.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:UniProtKB.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
//
ID   TOB2_HUMAN              Reviewed;         344 AA.
AC   Q14106; Q6FHR7; Q9BY97; Q9UBI0;
DE   RecName: Full=Protein Tob2;
DE   AltName: Full=Protein Tob4;
DE   AltName: Full=Transducer of erbB-2 2;
GN   Name=TOB2; Synonyms=KIAA1663, TOB4, TROB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0045778; P:positive regulation of ossification; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
//
ID   TOE1_HUMAN              Reviewed;         510 AA.
AC   Q96GM8; Q6IA35; Q8IWN5; Q9H846;
DE   RecName: Full=Target of EGR1 protein 1;
GN   Name=TOE1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TOIP1_HUMAN             Reviewed;         583 AA.
AC   Q5JTV8; A8K630; B0QZ57; Q5JTV6; Q8IZ65; Q9H8Y6; Q9HAJ1; Q9NV52;
AC   Q9Y3X5;
DE   RecName: Full=Torsin-1A-interacting protein 1;
DE   AltName: Full=Lamin-associated protein 1B;
DE            Short=LAP1B;
GN   Name=TOR1AIP1; Synonyms=LAP1;
DR   GO; GO:0001671; F:ATPase activator activity; IDA:UniProtKB.
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.
//
ID   TOIP2_HUMAN             Reviewed;         470 AA.
AC   Q8NFQ8;
DE   RecName: Full=Torsin-1A-interacting protein 2;
DE   AltName: Full=Lumenal domain-like LAP1;
GN   Name=TOR1AIP2; Synonyms=IFRG15, LULL1;
DR   GO; GO:0001671; F:ATPase activator activity; IDA:UniProtKB.
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IMP:UniProtKB.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; IDA:UniProtKB.
//
ID   TOLIP_HUMAN             Reviewed;         274 AA.
AC   Q9H0E2; Q9H9E6; Q9UJ69;
DE   RecName: Full=Toll-interacting protein;
GN   Name=TOLLIP;
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0035325; F:Toll-like receptor binding; IPI:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006954; P:inflammatory response; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0045321; P:leukocyte activation; NAS:UniProtKB.
DR   GO; GO:0016310; P:phosphorylation; IDA:UniProtKB.
DR   GO; GO:0033235; P:positive regulation of protein sumoylation; IEA:Ensembl.
DR   GO; GO:0036010; P:protein localization to endosome; IDA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IPI:UniProtKB.
//
ID   TOM1_HUMAN              Reviewed;         492 AA.
AC   O60784; B4DEL9; B4DNA1; Q5TIJ6; Q86X74;
DE   RecName: Full=Target of Myb protein 1;
GN   Name=TOM1;
DR   GO; GO:0030276; F:clathrin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; NAS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; NAS:UniProtKB.
//
ID   TOM20_HUMAN             Reviewed;         145 AA.
AC   Q15388; A8K195; Q498B3; Q6IBT4;
DE   RecName: Full=Mitochondrial import receptor subunit TOM20 homolog;
DE   AltName: Full=Mitochondrial 20 kDa outer membrane protein;
DE   AltName: Full=Outer mitochondrial membrane receptor Tom20;
GN   Name=TOMM20; Synonyms=KIAA0016;
DR   GO; GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:HGNC.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IDA:HGNC.
DR   GO; GO:0071806; P:protein transmembrane transport; IDA:GOC.
//
ID   TOM22_HUMAN             Reviewed;         142 AA.
AC   Q9NS69;
DE   RecName: Full=Mitochondrial import receptor subunit TOM22 homolog;
DE            Short=hTom22;
DE   AltName: Full=1C9-2;
DE   AltName: Full=Translocase of outer membrane 22 kDa subunit homolog;
GN   Name=TOMM22; Synonyms=TOM22;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0045040; P:protein import into mitochondrial outer membrane; IDA:BHF-UCL.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:HGNC.
//
ID   TOM34_HUMAN             Reviewed;         309 AA.
AC   Q15785; Q53GH9; Q6IBN7; Q9NTZ3;
DE   RecName: Full=Mitochondrial import receptor subunit TOM34;
DE            Short=hTom34;
DE   AltName: Full=Translocase of outer membrane 34 kDa subunit;
GN   Name=TOMM34; Synonyms=URCC3;
DR   GO; GO:0031072; F:heat shock protein binding; IPI:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IMP:UniProtKB.
//
ID   TOM40_HUMAN             Reviewed;         361 AA.
AC   O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95;
DE   RecName: Full=Mitochondrial import receptor subunit TOM40 homolog;
DE   AltName: Full=Protein Haymaker;
DE   AltName: Full=Translocase of outer membrane 40 kDa subunit homolog;
DE   AltName: Full=p38.5;
GN   Name=TOMM40; Synonyms=C19orf1, PEREC1, TOM40;
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; ISS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IMP:UniProtKB.
DR   GO; GO:0071806; P:protein transmembrane transport; ISS:GOC.
//
ID   TOM5_HUMAN              Reviewed;          51 AA.
AC   Q8N4H5; B2DG07; F6S928; Q5JRT7;
DE   RecName: Full=Mitochondrial import receptor subunit TOM5 homolog;
GN   Name=TOMM5; Synonyms=C9orf105, TOM5;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; IC:UniProtKB.
//
ID   TOM6_HUMAN              Reviewed;          74 AA.
AC   Q96B49; B2DG15; Q9UH52;
DE   RecName: Full=Mitochondrial import receptor subunit TOM6 homolog;
DE   AltName: Full=Overexpressed breast tumor protein;
DE   AltName: Full=Translocase of outer membrane 6 kDa subunit homolog;
GN   Name=TOMM6; Synonyms=OBTP, TOM6;
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome.
//
ID   TOM70_HUMAN             Reviewed;         608 AA.
AC   O94826; D3DN48;
DE   RecName: Full=Mitochondrial import receptor subunit TOM70;
DE   AltName: Full=Mitochondrial precursor proteins import receptor;
DE   AltName: Full=Translocase of outer membrane 70 kDa subunit;
GN   Name=TOMM70A; Synonyms=KIAA0719, TOM70;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:BHF-UCL.
DR   GO; GO:0071806; P:protein transmembrane transport; TAS:GOC.
//
ID   TOM7_HUMAN              Reviewed;          55 AA.
AC   Q9P0U1; O95939;
DE   RecName: Full=Mitochondrial import receptor subunit TOM7 homolog;
DE   AltName: Full=Translocase of outer membrane 7 kDa subunit homolog;
GN   Name=TOMM7; Synonyms=TOM7, TOMM07; ORFNames=AD-014;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:BHF-UCL.
//
ID   TOMT_HUMAN              Reviewed;         291 AA.
AC   Q8WZ04; B7Z816;
DE   RecName: Full=Transmembrane O-methyltransferase;
DE            EC=2.1.1.6;
DE   AltName: Full=Catechol O-methyltransferase 2;
DE   AltName: Full=Protein LRTOMT2;
GN   Name=LRTOMT; Synonyms=COMT2, TOMT; ORFNames=PP7517;
DR   GO; GO:0016206; F:catechol O-methyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0060117; P:auditory receptor cell development; ISS:UniProtKB.
DR   GO; GO:0042424; P:catecholamine catabolic process; ISS:UniProtKB.
DR   GO; GO:0042135; P:neurotransmitter catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; ISS:UniProtKB.
//
ID   TONSL_HUMAN             Reviewed;        1378 AA.
AC   Q96HA7; B5MDP0; C9JKB1; C9JNV8; Q13006; Q9UGJ2;
DE   RecName: Full=Tonsoku-like protein;
DE   AltName: Full=Inhibitor of kappa B-related protein;
DE            Short=I-kappa-B-related protein;
DE            Short=IkappaBR;
DE   AltName: Full=NF-kappa-B inhibitor-like protein 2;
DE   AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2;
GN   Name=TONSL; Synonyms=IKBR, NFKBIL2;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0031297; P:replication fork processing; IMP:UniProtKB.
//
ID   TOP1M_HUMAN             Reviewed;         601 AA.
AC   Q969P6; B7ZAR5; E7ES89; Q86ST4; Q86V82;
DE   RecName: Full=DNA topoisomerase I, mitochondrial;
DE            Short=TOP1mt;
DE            EC=5.99.1.2;
DE   Flags: Precursor;
GN   Name=TOP1MT;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IBA:RefGenome.
DR   GO; GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IBA:RefGenome.
DR   GO; GO:0006265; P:DNA topological change; IBA:RefGenome.
//
ID   TOP1_HUMAN              Reviewed;         765 AA.
AC   P11387; A8KA78; E1P5W3; O43256; Q12855; Q12856; Q15610; Q5TFY3;
AC   Q9UJN0;
DE   RecName: Full=DNA topoisomerase 1;
DE            EC=5.99.1.2;
DE   AltName: Full=DNA topoisomerase I;
GN   Name=TOP1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IDA:UniProtKB.
DR   GO; GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006338; P:chromatin remodeling; IBA:RefGenome.
DR   GO; GO:0007059; P:chromosome segregation; IBA:RefGenome.
DR   GO; GO:0006260; P:DNA replication; IBA:RefGenome.
DR   GO; GO:0006265; P:DNA topological change; IDA:UniProtKB.
DR   GO; GO:0040016; P:embryonic cleavage; IEA:Ensembl.
DR   GO; GO:0016310; P:phosphorylation; NAS:UniProtKB.
DR   GO; GO:0012501; P:programmed cell death; NAS:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TOP2A_HUMAN             Reviewed;        1531 AA.
AC   P11388; B2RTS1; Q71UN1; Q71UQ5; Q9HB24; Q9HB25; Q9HB26; Q9UP44;
AC   Q9UQP9;
DE   RecName: Full=DNA topoisomerase 2-alpha;
DE            EC=5.99.1.3;
DE   AltName: Full=DNA topoisomerase II, alpha isozyme;
GN   Name=TOP2A; Synonyms=TOP2;
DR   GuidetoPHARMACOLOGY; 2637; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0008301; F:DNA binding, bending; IDA:UniProtKB.
DR   GO; GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IDA:UniProtKB.
DR   GO; GO:0008144; F:drug binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IMP:UniProtKB.
DR   GO; GO:0030263; P:apoptotic chromosome condensation; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006266; P:DNA ligation; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006265; P:DNA topological change; IDA:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.
DR   GO; GO:0040016; P:embryonic cleavage; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006312; P:mitotic recombination; IBA:RefGenome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045870; P:positive regulation of single stranded viral RNA replication via double stranded DNA intermediate; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.
DR   GO; GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
//
ID   TOP2B_HUMAN             Reviewed;        1626 AA.
AC   Q02880; Q13600; Q9UMG8; Q9UQP8;
DE   RecName: Full=DNA topoisomerase 2-beta;
DE            EC=5.99.1.3;
DE   AltName: Full=DNA topoisomerase II, beta isozyme;
GN   Name=TOP2B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase type II (ATP-hydrolyzing) activity; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0007059; P:chromosome segregation; IBA:RefGenome.
DR   GO; GO:0006265; P:DNA topological change; IDA:UniProtKB.
DR   GO; GO:0006261; P:DNA-dependent DNA replication; IBA:RefGenome.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0006312; P:mitotic recombination; IBA:RefGenome.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.
DR   GO; GO:0000819; P:sister chromatid segregation; IBA:RefGenome.
//
ID   TOP3A_HUMAN             Reviewed;        1001 AA.
AC   Q13472; A8KA61; B4DK80; D3DXC7; Q13473;
DE   RecName: Full=DNA topoisomerase 3-alpha;
DE            EC=5.99.1.2;
DE   AltName: Full=DNA topoisomerase III alpha;
GN   Name=TOP3A; Synonyms=TOP3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IDA:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
//
ID   TOP3B_HUMAN             Reviewed;         862 AA.
AC   O95985; A0M8Q3; Q9BUP5;
DE   RecName: Full=DNA topoisomerase 3-beta-1;
DE            EC=5.99.1.2;
DE   AltName: Full=DNA topoisomerase III beta-1;
GN   Name=TOP3B; Synonyms=TOP3B1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003916; F:DNA topoisomerase activity; TAS:ProtInc.
DR   GO; GO:0003917; F:DNA topoisomerase type I activity; IEA:UniProtKB-EC.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:Ensembl.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
//
ID   TOPB1_HUMAN             Reviewed;        1522 AA.
AC   Q92547; B7Z7W8; Q7LGC1; Q9UEB9;
DE   RecName: Full=DNA topoisomerase 2-binding protein 1;
DE   AltName: Full=DNA topoisomerase II-beta-binding protein 1;
DE            Short=TopBP1;
DE   AltName: Full=DNA topoisomerase II-binding protein 1;
GN   Name=TOPBP1; Synonyms=KIAA0259;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006259; P:DNA metabolic process; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
//
ID   TOPK_HUMAN              Reviewed;         322 AA.
AC   Q96KB5; D3DST2; Q9NPD9; Q9NYL7; Q9NZK6;
DE   RecName: Full=Lymphokine-activated killer T-cell-originated protein kinase;
DE            EC=2.7.12.2;
DE   AltName: Full=Cancer/testis antigen 84;
DE            Short=CT84;
DE   AltName: Full=MAPKK-like protein kinase;
DE   AltName: Full=Nori-3;
DE   AltName: Full=PDZ-binding kinase;
DE   AltName: Full=Spermatogenesis-related protein kinase;
DE            Short=SPK;
DE   AltName: Full=T-LAK cell-originated protein kinase;
GN   Name=PBK; Synonyms=TOPK;
DR   GuidetoPHARMACOLOGY; 2140; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
//
ID   TOPRS_HUMAN             Reviewed;        1045 AA.
AC   Q9NS56; O43273; Q6P987; Q9NS55; Q9UNR9;
DE   RecName: Full=E3 ubiquitin-protein ligase Topors;
DE            EC=6.3.2.-;
DE   AltName: Full=SUMO1-protein E3 ligase Topors;
DE   AltName: Full=Topoisomerase I-binding RING finger protein;
DE   AltName: Full=Topoisomerase I-binding arginine/serine-rich protein;
DE   AltName: Full=Tumor suppressor p53-binding protein 3;
DE            Short=p53-binding protein 3;
DE            Short=p53BP3;
GN   Name=TOPORS; Synonyms=LUN, TP53BPL;
DR   GO; GO:0003823; F:antigen binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0044547; F:DNA topoisomerase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IDA:UniProtKB.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.
DR   GO; GO:0035845; P:photoreceptor cell outer segment organization; ISS:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0034504; P:protein localization to nucleus; IMP:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:BHF-UCL.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010842; P:retina layer formation; ISS:BHF-UCL.
DR   GO; GO:0046549; P:retinal cone cell development; ISS:BHF-UCL.
DR   GO; GO:0046548; P:retinal rod cell development; ISS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   TOPZ1_HUMAN             Reviewed;        1692 AA.
AC   Q8N9V7;
DE   RecName: Full=Testis- and ovary-specific PAZ domain-containing protein 1;
GN   Name=TOPAZ1; Synonyms=C3orf77;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   TOR1A_HUMAN             Reviewed;         332 AA.
AC   O14656; B2RB58; Q53Y64; Q96CA0;
DE   RecName: Full=Torsin-1A;
DE   AltName: Full=Dystonia 1 protein;
DE   AltName: Full=Torsin ATPase-1A;
DE            EC=3.6.4.-;
DE   AltName: Full=Torsin family 1 member A;
DE   Flags: Precursor;
GN   Name=TOR1A; Synonyms=DQ2, DYT1, TA, TORA;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; IMP:UniProtKB.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:InterPro.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IDA:UniProtKB.
DR   GO; GO:0072321; P:chaperone-mediated protein transport; IDA:UniProtKB.
DR   GO; GO:0071712; P:ER-associated misfolded protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0045104; P:intermediate filament cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.
DR   GO; GO:0071763; P:nuclear membrane organization; ISS:UniProtKB.
DR   GO; GO:0006996; P:organelle organization; ISS:UniProtKB.
DR   GO; GO:1900244; P:positive regulation of synaptic vesicle endocytosis; IMP:UniProtKB.
DR   GO; GO:0000338; P:protein deneddylation; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:MGI.
DR   GO; GO:0034504; P:protein localization to nucleus; IMP:UniProtKB.
DR   GO; GO:0051584; P:regulation of dopamine uptake involved in synaptic transmission; IDA:UniProtKB.
DR   GO; GO:2000008; P:regulation of protein localization to cell surface; IMP:UniProtKB.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0048489; P:synaptic vesicle transport; IMP:UniProtKB.
DR   GO; GO:0044319; P:wound healing, spreading of cells; ISS:UniProtKB.
//
ID   TOR1B_HUMAN             Reviewed;         336 AA.
AC   O14657;
DE   RecName: Full=Torsin-1B;
DE   AltName: Full=Torsin ATPase-1B;
DE            EC=3.6.4.-;
DE   AltName: Full=Torsin family 1 member B;
DE   Flags: Precursor;
GN   Name=TOR1B; Synonyms=DQ1; ORFNames=FKSG18;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:InterPro.
DR   GO; GO:0007029; P:endoplasmic reticulum organization; IDA:UniProtKB.
DR   GO; GO:0071763; P:nuclear membrane organization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:MGI.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
//
ID   TOR2A_HUMAN             Reviewed;         321 AA.
AC   Q5JU69; A4FU12; A4FU13; Q3ZCN9; Q3ZCP0; Q5JU68; Q66K87; Q6UXW6;
AC   Q8NAN5; Q96SL7;
DE   RecName: Full=Torsin-2A;
DE   AltName: Full=Torsin family 2 member A;
DE   AltName: Full=Torsin-related protein 1;
DE   Flags: Precursor;
GN   Name=TOR2A; Synonyms=TORP1; ORFNames=UNQ6408/PRO21181;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:InterPro.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:MGI.
//
ID   TOR2X_HUMAN             Reviewed;         242 AA.
AC   Q8N2E6;
DE   RecName: Full=Prosalusin;
DE   AltName: Full=Torsin family 2 member A;
DE   AltName: Full=Torsin-2A;
DE   Contains:
DE     RecName: Full=Salusin-alpha;
DE   Contains:
DE     RecName: Full=Salusin-beta;
DE   Flags: Precursor;
GN   Name=TOR2A; ORFNames=HEMBA1005096, PSEC0218;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:InterPro.
//
ID   TOR4A_HUMAN             Reviewed;         423 AA.
AC   Q9NXH8; A2BFA4;
DE   RecName: Full=Torsin-4A;
DE   AltName: Full=Torsin family 4 member A;
GN   Name=TOR4A; Synonyms=C9orf167;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:InterPro.
//
ID   TOR3A_HUMAN             Reviewed;         397 AA.
AC   Q9H497; B4DSY0; B7ZB65; Q5M7Y7; Q8WVA7; Q8WWM2; Q9H495; Q9H6E7;
DE   RecName: Full=Torsin-3A;
DE   AltName: Full=ATP-dependent interferon-responsive protein;
DE   AltName: Full=Torsin family 3 member A;
DE   Flags: Precursor;
GN   Name=TOR3A; Synonyms=ADIR;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:UniProtKB.
DR   GO; GO:0051085; P:chaperone mediated protein folding requiring cofactor; IEA:InterPro.
//
ID   TOX2_HUMAN              Reviewed;         488 AA.
AC   Q96NM4; A8K1J1; E1P5X0; G3XAC7; Q5TE33; Q5TE34; Q5TE35; Q96IC9;
AC   Q9BQN5;
DE   RecName: Full=TOX high mobility group box family member 2;
DE   AltName: Full=Granulosa cell HMG box protein 1;
DE            Short=GCX-1;
GN   Name=TOX2; Synonyms=C20orf100, GCX1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008585; P:female gonad development; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0034698; P:response to gonadotropin; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TOX3_HUMAN              Reviewed;         576 AA.
AC   O15405; B4DRD0; B5MCW4;
DE   RecName: Full=TOX high mobility group box family member 3;
DE   AltName: Full=CAG trinucleotide repeat-containing gene F9 protein;
DE   AltName: Full=Trinucleotide repeat-containing gene 9 protein;
GN   Name=TOX3; Synonyms=CAGF9, TNRC9;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0034056; F:estrogen response element binding; IDA:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TOX4_HUMAN              Reviewed;         621 AA.
AC   O94842; B4DPY8; E7EV69;
DE   RecName: Full=TOX high mobility group box family member 4;
DE   AltName: Full=Epidermal Langerhans cell protein LCP1;
GN   Name=TOX4; Synonyms=C14orf92, KIAA0737;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   TOX_HUMAN               Reviewed;         526 AA.
AC   O94900; Q96AV5;
DE   RecName: Full=Thymocyte selection-associated high mobility group box protein TOX;
DE   AltName: Full=Thymus high mobility group box protein TOX;
GN   Name=TOX; Synonyms=KIAA0808;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   TP4A1_HUMAN             Reviewed;         173 AA.
AC   Q93096; B2R6C8; O00648; Q49A54;
DE   RecName: Full=Protein tyrosine phosphatase type IVA 1;
DE            EC=3.1.3.48;
DE   AltName: Full=PTP(CAAXI);
DE   AltName: Full=Protein-tyrosine phosphatase 4a1;
DE   AltName: Full=Protein-tyrosine phosphatase of regenerating liver 1;
DE            Short=PRL-1;
DE   Flags: Precursor;
GN   Name=PTP4A1; Synonyms=PRL1, PTPCAAX1;
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; NAS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; NAS:GOC.
DR   GO; GO:0030335; P:positive regulation of cell migration; IEA:Ensembl.
//
ID   TP4A2_HUMAN             Reviewed;         167 AA.
AC   Q12974; A8K9I8; B4DM39; D3DPP0; E9PGJ6; O00649; Q15197; Q15259;
AC   Q15260; Q15261;
DE   RecName: Full=Protein tyrosine phosphatase type IVA 2;
DE            EC=3.1.3.48;
DE   AltName: Full=HU-PP-1;
DE   AltName: Full=OV-1;
DE   AltName: Full=PTP(CAAXII);
DE   AltName: Full=Protein-tyrosine phosphatase 4a2;
DE   AltName: Full=Protein-tyrosine phosphatase of regenerating liver 2;
DE            Short=PRL-2;
DE   Flags: Precursor;
GN   Name=PTP4A2; Synonyms=PRL2, PTPCAAX2; ORFNames=BM-008;
DR   GO; GO:0004727; F:prenylated protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
//
ID   TP4A3_HUMAN             Reviewed;         173 AA.
AC   O75365; Q8IVN5; Q99849; Q9BTW5;
DE   RecName: Full=Protein tyrosine phosphatase type IVA 3;
DE            EC=3.1.3.48;
DE   AltName: Full=PRL-R;
DE   AltName: Full=Protein-tyrosine phosphatase 4a3;
DE   AltName: Full=Protein-tyrosine phosphatase of regenerating liver 3;
DE            Short=PRL-3;
DE   Flags: Precursor;
GN   Name=PTP4A3; Synonyms=PRL3;
DR   GO; GO:0004727; F:prenylated protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
//
ID   TP4AP_HUMAN             Reviewed;         797 AA.
AC   Q8TEL6; E1P5Q0; E1P5Q1; Q96H82; Q9BVB8; Q9H429; Q9UFS6;
DE   RecName: Full=Short transient receptor potential channel 4-associated protein;
DE            Short=Trp4-associated protein;
DE            Short=Trpc4-associated protein;
DE   AltName: Full=Protein TAP1;
DE   AltName: Full=TNF-receptor ubiquitous scaffolding/signaling protein;
DE            Short=Protein TRUSS;
GN   Name=TRPC4AP; Synonyms=C20orf188, TRRP4AP;
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   TP53B_HUMAN             Reviewed;        1972 AA.
AC   Q12888; Q2M1Z7; Q4LE46; Q5FWZ3; Q7Z3U4;
DE   RecName: Full=Tumor suppressor p53-binding protein 1;
DE            Short=53BP1;
DE            Short=p53-binding protein 1;
DE            Short=p53BP1;
GN   Name=TP53BP1;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:Ensembl.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IMP:BHF-UCL.
DR   GO; GO:0042162; F:telomeric DNA binding; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:MGI.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IMP:GOC.
//
ID   TP8L1_HUMAN             Reviewed;         186 AA.
AC   Q8WVP5; D6W627;
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 8-like protein 1;
DE            Short=TNF alpha-induced protein 8-like protein 1;
DE            Short=TNFAIP8-like protein 1;
GN   Name=TNFAIP8L1;
//
ID   TP8L2_HUMAN             Reviewed;         184 AA.
AC   Q6P589; Q6I9Y0; Q9H2H7; Q9H5G2;
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 8-like protein 2;
DE            Short=TIPE2;
DE            Short=TNF alpha-induced protein 8-like protein 2;
DE            Short=TNFAIP8-like protein 2;
DE   AltName: Full=Inflammation factor protein 20;
GN   Name=TNFAIP8L2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IEA:Ensembl.
//
ID   TP8L3_HUMAN             Reviewed;         292 AA.
AC   Q5GJ75; Q6ZWD1;
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 8-like protein 3;
DE            Short=TNF alpha-induced protein 8-like protein 3;
DE            Short=TNFAIP8-like protein 3;
GN   Name=TNFAIP8L3;
//
ID   TPA_HUMAN               Reviewed;         562 AA.
AC   P00750; A8K022; B2R8E8; Q15103; Q503B0; Q6PJA5; Q7Z7N2; Q86YK8;
AC   Q9BU99; Q9BZW1;
DE   RecName: Full=Tissue-type plasminogen activator;
DE            Short=t-PA;
DE            Short=t-plasminogen activator;
DE            Short=tPA;
DE            EC=3.4.21.68;
DE   AltName: INN=Alteplase;
DE   AltName: INN=Reteplase;
DE   Contains:
DE     RecName: Full=Tissue-type plasminogen activator chain A;
DE   Contains:
DE     RecName: Full=Tissue-type plasminogen activator chain B;
DE   Flags: Precursor;
GN   Name=PLAT;
DR   GuidetoPHARMACOLOGY; 2392; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0045861; P:negative regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0031639; P:plasminogen activation; IDA:UniProtKB.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0060279; P:positive regulation of ovulation; IEA:Ensembl.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0048167; P:regulation of synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0014909; P:smooth muscle cell migration; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
//
ID   TPBGL_HUMAN             Reviewed;         382 AA.
AC   P0DKB5;
DE   RecName: Full=Trophoblast glycoprotein-like;
DE   Flags: Precursor;
GN   Name=TPBGL;
//
ID   TPBG_HUMAN              Reviewed;         420 AA.
AC   Q13641; A8K555;
DE   RecName: Full=Trophoblast glycoprotein;
DE   AltName: Full=5T4 oncofetal antigen;
DE   AltName: Full=5T4 oncofetal trophoblast glycoprotein;
DE            Short=5T4 oncotrophoblast glycoprotein;
DE   AltName: Full=M6P1;
DE   AltName: Full=Wnt-activated inhibitory factor 1;
DE            Short=WAIF1;
DE   Flags: Precursor;
GN   Name=TPBG; Synonyms=5T4;
DR   GO; GO:0007155; P:cell adhesion; NAS:ProtInc.
//
ID   TPC10_HUMAN             Reviewed;        1259 AA.
AC   P48553; Q3MIR2; Q9UMD4; Q9Y4L3;
DE   RecName: Full=Trafficking protein particle complex subunit 10;
DE   AltName: Full=Epilepsy holoprosencephaly candidate 1 protein;
DE            Short=EHOC-1;
DE   AltName: Full=Protein GT334;
DE   AltName: Full=Trafficking protein particle complex subunit TMEM1;
DE   AltName: Full=Transport protein particle subunit TMEM1;
DE            Short=TRAPP subunit TMEM1;
GN   Name=TRAPPC10; Synonyms=EHOC1, TMEM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015081; F:sodium ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; TAS:GOC.
DR   GO; GO:0006814; P:sodium ion transport; TAS:ProtInc.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPC11_HUMAN             Reviewed;        1133 AA.
AC   Q7Z392; A4QPB8; B2RCD6; Q5U5I7; Q6FI73; Q86T25; Q9H0L1; Q9H5K9;
AC   Q9H8Q1; Q9H9I7;
DE   RecName: Full=Trafficking protein particle complex subunit 11;
GN   Name=TRAPPC11; Synonyms=C4orf41;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPC12_HUMAN             Reviewed;         735 AA.
AC   Q8WVT3; B3KV01; D6W4Y2; Q8WVW1; Q9Y395;
DE   RecName: Full=Trafficking protein particle complex subunit 12;
DE   AltName: Full=Tetratricopeptide repeat protein 15;
DE            Short=TPR repeat protein 15;
DE            Short=TTC-15;
GN   Name=TRAPPC12; Synonyms=TTC15; ORFNames=CGI-87;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPC13_HUMAN             Reviewed;         417 AA.
AC   A5PLN9; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3;
DE   RecName: Full=Trafficking protein particle complex subunit 13;
GN   Name=TRAPPC13; Synonyms=C5orf44;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TPC1_HUMAN              Reviewed;         816 AA.
AC   Q9ULQ1; A7E258; Q86XS9; Q8NC20;
DE   RecName: Full=Two pore calcium channel protein 1;
DE   AltName: Full=Voltage-dependent calcium channel protein TPC1;
GN   Name=TPCN1; Synonyms=KIAA1169, TPC1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0072345; F:NAADP-sensitive calcium-release channel activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IBA:RefGenome.
DR   GO; GO:0006816; P:calcium ion transport; IBA:RefGenome.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TPC2A_HUMAN             Reviewed;         140 AA.
AC   P0DI81; A6NEG0; O14582; Q9HD16;
DE   RecName: Full=Trafficking protein particle complex subunit 2;
DE   AltName: Full=Sedlin;
GN   Name=TRAPPC2; Synonyms=SEDL;
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001501; P:skeletal system development; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TPC2B_HUMAN             Reviewed;         140 AA.
AC   P0DI82; A6NEG0; O14582; Q9HD16;
DE   RecName: Full=Trafficking protein particle complex subunit 2 protein TRAPPC2P1;
DE   AltName: Full=MBP-1-interacting protein 2A;
DE            Short=MIP-2A;
GN   Name=TRAPPC2P1; Synonyms=SEDLP1, TRAPPC2.19;
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TPC2L_HUMAN             Reviewed;         140 AA.
AC   Q9UL33; B2R4M9; Q6ZTA7; Q9NZZ4;
DE   RecName: Full=Trafficking protein particle complex subunit 2-like protein;
GN   Name=TRAPPC2L; ORFNames=HSPC126;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
//
ID   TPC2_HUMAN              Reviewed;         752 AA.
AC   Q8NHX9; Q9NT82;
DE   RecName: Full=Two pore calcium channel protein 2;
DE   AltName: Full=Voltage-dependent calcium channel protein TPC2;
GN   Name=TPCN2; Synonyms=TPC2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0072345; F:NAADP-sensitive calcium-release channel activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IBA:RefGenome.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:RefGenome.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:RefGenome.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IEA:Ensembl.
DR   GO; GO:0006939; P:smooth muscle contraction; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TPC6A_HUMAN             Reviewed;         159 AA.
AC   O75865; K7ERB1; K7ERQ4; Q9BQ45; Q9P092;
DE   RecName: Full=Trafficking protein particle complex subunit 6A;
DE            Short=TRAPP complex subunit 6A;
GN   Name=TRAPPC6A; ORFNames=HSPC289;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPC3L_HUMAN             Reviewed;         181 AA.
AC   Q5T215; Q5T213; Q5T214;
DE   RecName: Full=Trafficking protein particle complex subunit 3-like protein;
DE            Short=TRAPPC3-like protein;
DE   AltName: Full=BET3-like protein;
GN   Name=TRAPPC3L; Synonyms=BET3L;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPC6B_HUMAN             Reviewed;         158 AA.
AC   Q86SZ2; B3KPS2; Q5JPD6; Q86U35; Q86X35;
DE   RecName: Full=Trafficking protein particle complex subunit 6B;
GN   Name=TRAPPC6B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPC_HUMAN               Reviewed;         320 AA.
AC   Q9HC21; E9PF74; Q6V9R7;
DE   RecName: Full=Mitochondrial thiamine pyrophosphate carrier;
DE   AltName: Full=Mitochondrial uncoupling protein 1;
DE   AltName: Full=Solute carrier family 25 member 19;
GN   Name=SLC25A19; Synonyms=DNC, MUP1;
DR   GO; GO:0030233; F:deoxynucleotide transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0030302; P:deoxynucleotide transport; NAS:UniProtKB.
//
ID   TPD52_HUMAN             Reviewed;         224 AA.
AC   P55327; B7Z414; C9J502; D0UFD1; D0UFD2; D0UFD3; D0UFD4; D0UFD5;
AC   E5RKB4; Q13056; Q53EK8; Q6FGP3; Q6FGS3; Q86YZ2; Q9UCX8;
DE   RecName: Full=Tumor protein D52;
DE   AltName: Full=Protein N8;
GN   Name=TPD52;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0030183; P:B cell differentiation; IEP:UniProtKB.
DR   GO; GO:0046903; P:secretion; TAS:UniProtKB.
//
ID   TPD53_HUMAN             Reviewed;         204 AA.
AC   Q16890; A8K757; A8K772; A8MUD2; A8MUJ7; A8MW70; O43397; Q5TC99;
AC   Q5TDQ0; Q9BUQ6; Q9C054;
DE   RecName: Full=Tumor protein D53;
DE            Short=hD53;
DE   AltName: Full=Tumor protein D52-like 1;
GN   Name=TPD52L1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0043281; P:regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
//
ID   TPD54_HUMAN             Reviewed;         206 AA.
AC   O43399; B4DPJ6; E1P5G7; O43398; Q5JWU5; Q5JWU6; Q5JWU8; Q5U0E0;
AC   Q9H3Z6;
DE   RecName: Full=Tumor protein D54;
DE            Short=hD54;
DE   AltName: Full=Tumor protein D52-like 2;
GN   Name=TPD52L2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
//
ID   TPD55_HUMAN             Reviewed;         140 AA.
AC   Q96J77; Q5TCR3; Q5TCR4; Q5TCR5; Q8N4P5; Q8WWF7; Q96M09;
DE   RecName: Full=Tumor protein D55;
DE            Short=hD55;
DE   AltName: Full=Testis development protein NYD-SP25;
DE   AltName: Full=Tumor protein D52-like 3;
GN   Name=TPD52L3;
//
ID   TPGS1_HUMAN             Reviewed;         290 AA.
AC   Q6ZTW0; Q96GE2;
DE   RecName: Full=Tubulin polyglutamylase complex subunit 1;
DE            Short=PGs1;
GN   Name=TPGS1; Synonyms=C19orf20;
DR   GO; GO:0070740; F:tubulin-glutamic acid ligase activity; IEA:Ensembl.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0018095; P:protein polyglutamylation; IEA:Ensembl.
DR   GO; GO:0007288; P:sperm axoneme assembly; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0051648; P:vesicle localization; IEA:Ensembl.
//
ID   TPGS2_HUMAN             Reviewed;         300 AA.
AC   Q68CL5; B4DIX2; Q4KN59; Q8WTU3; Q96BT9; Q9Y435;
DE   RecName: Full=Tubulin polyglutamylase complex subunit 2;
DE            Short=PGs2;
GN   Name=TPGS2; Synonyms=C18orf10; ORFNames=HMFN0601, L17;
//
ID   TPH1_HUMAN              Reviewed;         444 AA.
AC   P17752; D3DQX6; O95188; O95189; Q16736; Q3KPG8;
DE   RecName: Full=Tryptophan 5-hydroxylase 1;
DE            EC=1.14.16.4;
DE   AltName: Full=Tryptophan 5-monooxygenase 1;
GN   Name=TPH1; Synonyms=TPH, TPRH, TRPH;
DR   GuidetoPHARMACOLOGY; 1241; -.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004510; F:tryptophan 5-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009072; P:aromatic amino acid family metabolic process; IEA:InterPro.
DR   GO; GO:0046849; P:bone remodeling; IEA:Ensembl.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0046219; P:indolalkylamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0060749; P:mammary gland alveolus development; IEA:Ensembl.
DR   GO; GO:0030279; P:negative regulation of ossification; IEA:Ensembl.
DR   GO; GO:0035902; P:response to immobilization stress; IEA:Ensembl.
DR   GO; GO:0042427; P:serotonin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TPH2_HUMAN              Reviewed;         490 AA.
AC   Q8IWU9; A6NGA4; Q14CB0;
DE   RecName: Full=Tryptophan 5-hydroxylase 2;
DE            EC=1.14.16.4;
DE   AltName: Full=Neuronal tryptophan hydroxylase;
DE   AltName: Full=Tryptophan 5-monooxygenase 2;
GN   Name=TPH2; Synonyms=NTPH;
DR   GuidetoPHARMACOLOGY; 1242; -.
DR   GO; GO:0016597; F:amino acid binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004510; F:tryptophan 5-monooxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009072; P:aromatic amino acid family metabolic process; IEA:InterPro.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0046219; P:indolalkylamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0042427; P:serotonin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TPIP1_HUMAN             Reviewed;         124 AA.
AC   Q9HCN2; Q6NT40; Q7Z6F7; Q9HCN0; Q9HCN1;
DE   RecName: Full=p53-regulated apoptosis-inducing protein 1;
DE            Short=p53AIP1;
GN   Name=TP53AIP1;
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
//
ID   TPIS_HUMAN              Reviewed;         286 AA.
AC   P60174; B7Z5D8; D3DUS9; P00938; Q6FHP9; Q6IS07; Q8WWD0; Q96AG5;
DE   RecName: Full=Triosephosphate isomerase;
DE            Short=TIM;
DE            EC=5.3.1.1;
DE   AltName: Full=Triose-phosphate isomerase;
GN   Name=TPI1; Synonyms=TPI;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004807; F:triose-phosphate isomerase activity; NAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0019682; P:glyceraldehyde-3-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0006096; P:glycolytic process; TAS:Reactome.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-KW.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TPK1_HUMAN              Reviewed;         243 AA.
AC   Q9H3S4; A8K0T7; D3DWG0; Q6NUR5; Q9H602;
DE   RecName: Full=Thiamin pyrophosphokinase 1;
DE            Short=hTPK1;
DE            EC=2.7.6.2;
DE   AltName: Full=Placental protein 20;
DE            Short=PP20;
DE   AltName: Full=Thiamine pyrophosphokinase 1;
GN   Name=TPK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004788; F:thiamine diphosphokinase activity; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006772; P:thiamine metabolic process; IEA:Ensembl.
DR   GO; GO:0042723; P:thiamine-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   TPM1_HUMAN              Reviewed;         284 AA.
AC   P09493; B7Z5T7; D9YZV2; D9YZV3; D9YZV8; P09494; P10469; Q6DV89;
AC   Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427;
DE   RecName: Full=Tropomyosin alpha-1 chain;
DE   AltName: Full=Alpha-tropomyosin;
DE   AltName: Full=Tropomyosin-1;
GN   Name=TPM1; Synonyms=C15orf13, TMSA;
DR   GO; GO:0003779; F:actin binding; TAS:BHF-UCL.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IPI:UniProtKB.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:BHF-UCL.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0060048; P:cardiac muscle contraction; IMP:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0034614; P:cellular response to reactive oxygen species; IEP:BHF-UCL.
DR   GO; GO:0007010; P:cytoskeleton organization; TAS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030049; P:muscle filament sliding; ISS:BHF-UCL.
DR   GO; GO:0030336; P:negative regulation of cell migration; ISS:BHF-UCL.
DR   GO; GO:0032781; P:positive regulation of ATPase activity; ISS:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0003065; P:positive regulation of heart rate by epinephrine; ISS:BHF-UCL.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; ISS:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; TAS:ProtInc.
DR   GO; GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.
DR   GO; GO:0031529; P:ruffle organization; ISS:BHF-UCL.
DR   GO; GO:0045214; P:sarcomere organization; IMP:BHF-UCL.
DR   GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0042060; P:wound healing; ISS:BHF-UCL.
//
ID   TPM2_HUMAN              Reviewed;         284 AA.
AC   P07951; A6NM85; P06468; Q13894; Q53FM4; Q5TCU4; Q5TCU7; Q9UH67;
DE   RecName: Full=Tropomyosin beta chain;
DE   AltName: Full=Beta-tropomyosin;
DE   AltName: Full=Tropomyosin-2;
GN   Name=TPM2; Synonyms=TMSB;
DR   GO; GO:0003779; F:actin binding; IDA:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0043462; P:regulation of ATPase activity; IDA:UniProtKB.
//
ID   TPM3_HUMAN              Reviewed;         285 AA.
AC   P06753; D3DV71; P12324; Q2QD06; Q5VU58; Q5VU63; Q5VU66; Q5VU71;
AC   Q5VU72; Q8TCG3; Q969Q2; Q9NQH8;
DE   RecName: Full=Tropomyosin alpha-3 chain;
DE   AltName: Full=Gamma-tropomyosin;
DE   AltName: Full=Tropomyosin-3;
DE   AltName: Full=Tropomyosin-5;
DE            Short=hTM5;
GN   Name=TPM3;
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
//
ID   TPM4_HUMAN              Reviewed;         248 AA.
AC   P67936; P07226; Q15659; Q5U0D9; Q9BU85; Q9H8Q3; Q9UCS1; Q9UCS2;
AC   Q9UCS3; Q9UCS4;
DE   RecName: Full=Tropomyosin alpha-4 chain;
DE   AltName: Full=TM30p1;
DE   AltName: Full=Tropomyosin-4;
GN   Name=TPM4;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
//
ID   TPMT_HUMAN              Reviewed;         245 AA.
AC   P51580; O14806; O15423; O15424; O15425; O15426; O15515; O15548;
AC   O43213; Q5VUK6; Q9UBE6; Q9UBT8; Q9UE62;
DE   RecName: Full=Thiopurine S-methyltransferase;
DE            EC=2.1.1.67;
DE   AltName: Full=Thiopurine methyltransferase;
GN   Name=TPMT;
DR   GO; GO:0008119; F:thiopurine S-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0032259; P:methylation; TAS:Reactome.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   TPOR_HUMAN              Reviewed;         635 AA.
AC   P40238; Q5JUZ0;
DE   RecName: Full=Thrombopoietin receptor;
DE            Short=TPO-R;
DE   AltName: Full=Myeloproliferative leukemia protein;
DE   AltName: Full=Proto-oncogene c-Mpl;
DE   AltName: CD_antigen=CD110;
DE   Flags: Precursor;
GN   Name=MPL; Synonyms=TPOR;
DR   GuidetoPHARMACOLOGY; 1722; -.
DR   GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0032642; P:regulation of chemokine production; IEA:Ensembl.
//
ID   TPO_HUMAN               Reviewed;         353 AA.
AC   P40225; A1L3Y0; B7ZLR8; B9EGA8; Q13020; Q15790; Q15791; Q15792;
DE   RecName: Full=Thrombopoietin;
DE   AltName: Full=C-mpl ligand;
DE            Short=ML;
DE   AltName: Full=Megakaryocyte colony-stimulating factor;
DE   AltName: Full=Megakaryocyte growth and development factor;
DE            Short=MGDF;
DE   AltName: Full=Myeloproliferative leukemia virus oncogene ligand;
DE   Flags: Precursor;
GN   Name=THPO; Synonyms=MGDF;
DR   GO; GO:0008083; F:growth factor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0030099; P:myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0038163; P:thrombopoietin-mediated signaling pathway; ISS:UniProtKB.
//
ID   TPP1_HUMAN              Reviewed;         563 AA.
AC   O14773; Q53HT1; Q5JAK6; Q6UX56; Q71JP6; Q96C37;
DE   RecName: Full=Tripeptidyl-peptidase 1;
DE            Short=TPP-1;
DE            EC=3.4.14.9;
DE   AltName: Full=Cell growth-inhibiting gene 1 protein;
DE   AltName: Full=Lysosomal pepstatin-insensitive protease;
DE            Short=LPIC;
DE   AltName: Full=Tripeptidyl aminopeptidase;
DE   AltName: Full=Tripeptidyl-peptidase I;
DE            Short=TPP-I;
DE   Flags: Precursor;
GN   Name=TPP1; Synonyms=CLN2; ORFNames=GIG1, UNQ267/PRO304;
DR   GO; GO:0004175; F:endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IMP:UniProtKB.
DR   GO; GO:0042277; F:peptide binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; IMP:UniProtKB.
DR   GO; GO:0008240; F:tripeptidyl-peptidase activity; IDA:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0007040; P:lysosome organization; ISS:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IMP:UniProtKB.
DR   GO; GO:0050885; P:neuromuscular process controlling balance; ISS:UniProtKB.
DR   GO; GO:0043171; P:peptide catabolic process; IMP:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
//
ID   TPP2_HUMAN              Reviewed;        1249 AA.
AC   P29144; Q5VZU8;
DE   RecName: Full=Tripeptidyl-peptidase 2;
DE            Short=TPP-2;
DE            EC=3.4.14.10;
DE   AltName: Full=Tripeptidyl aminopeptidase;
DE   AltName: Full=Tripeptidyl-peptidase II;
DE            Short=TPP-II;
GN   Name=TPP2;
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004175; F:endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0008240; F:tripeptidyl-peptidase activity; TAS:ProtInc.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; IBA:RefGenome.
//
ID   TPPC1_HUMAN             Reviewed;         145 AA.
AC   Q9Y5R8; D3DTR0;
DE   RecName: Full=Trafficking protein particle complex subunit 1;
DE   AltName: Full=BET5 homolog;
DE   AltName: Full=Multiple myeloma protein 2;
DE            Short=MUM-2;
GN   Name=TRAPPC1; Synonyms=BET5, MUM2;
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
//
ID   TPPC3_HUMAN             Reviewed;         180 AA.
AC   O43617; A6NDN0; B2RDN2; D3DPS2;
DE   RecName: Full=Trafficking protein particle complex subunit 3;
DE   AltName: Full=BET3 homolog;
GN   Name=TRAPPC3; Synonyms=BET3; ORFNames=CDABP0066;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:Ensembl.
//
ID   TPPC4_HUMAN             Reviewed;         219 AA.
AC   Q9Y296; A8K3A5;
DE   RecName: Full=Trafficking protein particle complex subunit 4;
DE   AltName: Full=Hematopoietic stem/progenitor cell protein 172;
DE   AltName: Full=Synbindin;
DE   AltName: Full=TRS23 homolog;
GN   Name=TRAPPC4; Synonyms=SBDN; ORFNames=CGI-104, HSPC172, PTD009;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016358; P:dendrite development; ISS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   TPPC5_HUMAN             Reviewed;         188 AA.
AC   Q8IUR0; A8K7I6;
DE   RecName: Full=Trafficking protein particle complex subunit 5;
GN   Name=TRAPPC5;
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPPC8_HUMAN             Reviewed;        1435 AA.
AC   Q9Y2L5; A0JP15; B3KME5; Q9H0L2;
DE   RecName: Full=Trafficking protein particle complex subunit 8;
DE   AltName: Full=Protein TRS85 homolog;
GN   Name=TRAPPC8; Synonyms=KIAA1012;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   TPPC9_HUMAN             Reviewed;        1148 AA.
AC   Q96Q05; Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96SL2;
AC   Q9BQA2;
DE   RecName: Full=Trafficking protein particle complex subunit 9;
DE   AltName: Full=NIK- and IKBKB-binding protein;
DE   AltName: Full=Tularik gene 1 protein;
GN   Name=TRAPPC9; Synonyms=KIAA1882, NIBP; ORFNames=T1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   TPPP2_HUMAN             Reviewed;         170 AA.
AC   P59282; Q2VYF3;
DE   RecName: Full=Tubulin polymerization-promoting protein family member 2;
DE   AltName: Full=Protein p25-beta;
DE   AltName: Full=TPPP/p18;
GN   Name=TPPP2; Synonyms=C14orf8;
//
ID   TPPP3_HUMAN             Reviewed;         176 AA.
AC   Q9BW30; Q49AH9; Q9Y326; Q9Y6H0;
DE   RecName: Full=Tubulin polymerization-promoting protein family member 3;
DE   AltName: Full=TPPP/p20;
GN   Name=TPPP3; ORFNames=CGI-38;
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.
//
ID   TPPP_HUMAN              Reviewed;         219 AA.
AC   O94811;
DE   RecName: Full=Tubulin polymerization-promoting protein;
DE            Short=TPPP;
DE   AltName: Full=25 kDa brain-specific protein;
DE   AltName: Full=TPPP/p25;
DE   AltName: Full=p24;
DE   AltName: Full=p25-alpha;
GN   Name=TPPP; Synonyms=TPPP1;
DR   GO; GO:0008017; F:microtubule binding; ISS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IDA:UniProtKB.
DR   GO; GO:0046785; P:microtubule polymerization; IDA:UniProtKB.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; ISS:HGNC.
DR   GO; GO:0032273; P:positive regulation of protein polymerization; IDA:HGNC.
//
ID   TPRA1_HUMAN             Reviewed;         373 AA.
AC   Q86W33; A8MVB8; D3DNA9; Q8WZ24; Q96AJ6; Q9P2R4;
DE   RecName: Full=Transmembrane protein adipocyte-associated 1;
DE   AltName: Full=Integral membrane protein GPR175;
DE   AltName: Full=Transmembrane protein 227;
GN   Name=TPRA1; Synonyms=GPR175, TMEM227; ORFNames=PP6566;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:GOC.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
//
ID   TPRG1_HUMAN             Reviewed;         275 AA.
AC   Q6ZUI0;
DE   RecName: Full=Tumor protein p63-regulated gene 1 protein;
DE   AltName: Full=Protein FAM79B;
GN   Name=TPRG1; Synonyms=FAM79B;
//
ID   TPRGL_HUMAN             Reviewed;         272 AA.
AC   Q5T0D9; A8K1K4; Q8WV04;
DE   RecName: Full=Tumor protein p63-regulated gene 1-like protein;
DE   AltName: Full=Mossy fiber terminal-associated vertebrate-specific presynaptic protein;
DE   AltName: Full=Protein FAM79A;
GN   Name=TPRG1L; Synonyms=FAM79A, MOVER;
//
ID   TPRKB_HUMAN             Reviewed;         175 AA.
AC   Q9Y3C4; D6W5H6; Q8IWR6; Q8IWR7; Q9H3K4;
DE   RecName: Full=EKC/KEOPS complex subunit TPRKB;
DE   AltName: Full=PRPK-binding protein;
DE   AltName: Full=TP53RK-binding protein;
GN   Name=TPRKB; ORFNames=CGI-121, My019;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TPRN_HUMAN              Reviewed;         711 AA.
AC   Q4KMQ1; B7ZKU5; Q5VSG5; Q5VSG6; Q6IPP2; Q8NCH2;
DE   RecName: Full=Taperin;
GN   Name=TPRN; Synonyms=C9orf75;
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
//
ID   TPRX1_HUMAN             Reviewed;         411 AA.
AC   Q8N7U7; A5D8Y3; B2RPL5;
DE   RecName: Full=Tetra-peptide repeat homeobox protein 1;
GN   Name=TPRX1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
//
ID   TPRXL_HUMAN             Reviewed;         258 AA.
AC   Q17RH7; Q8NAM5;
DE   RecName: Full=Putative protein TPRXL;
GN   Name=TPRXL;
//
ID   TPR_HUMAN               Reviewed;        2363 AA.
AC   P12270; Q15655; Q5SWY0; Q99968;
DE   RecName: Full=Nucleoprotein TPR;
DE   AltName: Full=Megator;
DE   AltName: Full=NPC-associated intranuclear protein;
DE   AltName: Full=Translocated promoter region protein;
GN   Name=TPR;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0070840; F:dynein complex binding; IDA:UniProtKB.
DR   GO; GO:0031072; F:heat shock protein binding; IDA:UniProtKB.
DR   GO; GO:0051019; F:mitogen-activated protein kinase binding; IDA:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0005487; F:nucleocytoplasmic transporter activity; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0004828; F:serine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0015631; F:tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0034605; P:cellular response to heat; IDA:UniProtKB.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; ISS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; TAS:Reactome.
DR   GO; GO:0008645; P:hexose transport; TAS:Reactome.
DR   GO; GO:0000189; P:MAPK import into nucleus; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0031990; P:mRNA export from nucleus in response to heat stress; IDA:UniProtKB.
DR   GO; GO:0046832; P:negative regulation of RNA export from nucleus; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IMP:UniProtKB.
DR   GO; GO:0006999; P:nuclear pore organization; IMP:UniProtKB.
DR   GO; GO:0031453; P:positive regulation of heterochromatin assembly; IMP:UniProtKB.
DR   GO; GO:0090316; P:positive regulation of intracellular protein transport; IMP:UniProtKB.
DR   GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; ISS:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IMP:UniProtKB.
DR   GO; GO:0006606; P:protein import into nucleus; TAS:ProtInc.
DR   GO; GO:0010827; P:regulation of glucose transport; TAS:Reactome.
DR   GO; GO:0010965; P:regulation of mitotic sister chromatid separation; IMP:UniProtKB.
DR   GO; GO:1901673; P:regulation of spindle assembly involved in mitosis; IMP:UniProtKB.
DR   GO; GO:0070849; P:response to epidermal growth factor; IDA:UniProtKB.
DR   GO; GO:0006405; P:RNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0006404; P:RNA import into nucleus; IDA:UniProtKB.
DR   GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   TPSNR_HUMAN             Reviewed;         468 AA.
AC   Q9BX59; Q9NWB8;
DE   RecName: Full=Tapasin-related protein;
DE            Short=TAPASIN-R;
DE   AltName: Full=TAP-binding protein-like;
DE   AltName: Full=TAP-binding protein-related protein;
DE            Short=TAPBP-R;
DE   AltName: Full=Tapasin-like;
DE   Flags: Precursor;
GN   Name=TAPBPL;
//
ID   TPSN_HUMAN              Reviewed;         448 AA.
AC   O15533; A2AB91; A2ABC0; B0V003; B0V0A6; B2ZUA4; E9PGM2; O15210;
AC   O15272; Q5STJ8; Q5STK6; Q5STQ5; Q5STQ6; Q66K65; Q96KK7; Q9HAN8;
AC   Q9UEE0; Q9UEE4; Q9UIZ6; Q9Y6K2;
DE   RecName: Full=Tapasin;
DE            Short=TPN;
DE            Short=TPSN;
DE   AltName: Full=NGS-17;
DE   AltName: Full=TAP-associated protein;
DE   AltName: Full=TAP-binding protein;
DE   Flags: Precursor;
GN   Name=TAPBP; Synonyms=NGS17, TAPA;
DR   GO; GO:0042288; F:MHC class I protein binding; TAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; TAS:UniProtKB.
DR   GO; GO:0015433; F:peptide antigen-transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046978; F:TAP1 binding; IPI:UniProtKB.
DR   GO; GO:0046979; F:TAP2 binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:UniProtKB.
DR   GO; GO:0042886; P:amide transport; TAS:GOC.
DR   GO; GO:0019885; P:antigen processing and presentation of endogenous peptide antigen via MHC class I; IEA:InterPro.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0050823; P:peptide antigen stabilization; ISS:UniProtKB.
DR   GO; GO:0015833; P:peptide transport; TAS:GOC.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; NAS:UniProtKB.
//
ID   TPST1_HUMAN             Reviewed;         370 AA.
AC   O60507; A4D2M0; Q6FGM7;
DE   RecName: Full=Protein-tyrosine sulfotransferase 1;
DE            EC=2.8.2.20;
DE   AltName: Full=Tyrosylprotein sulfotransferase 1;
DE            Short=TPST-1;
GN   Name=TPST1;
DR   GO; GO:0008476; F:protein-tyrosine sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0006478; P:peptidyl-tyrosine sulfation; TAS:ProtInc.
//
ID   TPST2_HUMAN             Reviewed;         377 AA.
AC   O60704; B3KQA7; Q6FI98; Q9H0V4;
DE   RecName: Full=Protein-tyrosine sulfotransferase 2;
DE            EC=2.8.2.20;
DE   AltName: Full=Tyrosylprotein sulfotransferase 2;
DE            Short=TPST-2;
GN   Name=TPST2;
DR   GO; GO:0008476; F:protein-tyrosine sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0007342; P:fusion of sperm to egg plasma membrane; IEA:Ensembl.
DR   GO; GO:0006478; P:peptidyl-tyrosine sulfation; TAS:ProtInc.
DR   GO; GO:0060468; P:prevention of polyspermy; IEA:Ensembl.
//
ID   TPT1L_HUMAN             Reviewed;         140 AA.
AC   Q56UQ5; B2RPQ9; Q6ZTI1;
DE   RecName: Full=TPT1-like protein;
//
ID   TPT2L_HUMAN             Reviewed;         138 AA.
AC   Q5T6R2; B3KST4; B4DMH9;
DE   RecName: Full=Putative phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2P1;
GN   Name=TPTE2P1;
//
ID   TPTE2_HUMAN             Reviewed;         522 AA.
AC   Q6XPS3; A1A4X0; A1A4X1; A8MX64; B1AQ16; B4DWZ2; Q5VUH2; Q8WWL4;
AC   Q8WWL5;
DE   RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2;
DE            EC=3.1.3.67;
DE   AltName: Full=Lipid phosphatase TPIP;
DE   AltName: Full=TPTE and PTEN homologous inositol lipid phosphatase;
GN   Name=TPTE2; Synonyms=TPIP;
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0016314; F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TPTE_HUMAN              Reviewed;         551 AA.
AC   P56180; B2RAP7; C9J6D6; C9JKK8; Q6XPS4; Q6XPS5; Q71JA8; Q8NCS8;
DE   RecName: Full=Putative tyrosine-protein phosphatase TPTE;
DE            EC=3.1.3.48;
DE   AltName: Full=Cancer/testis antigen 44;
DE            Short=CT44;
DE   AltName: Full=Transmembrane phosphatase with tensin homology;
DE   AltName: Full=Tumor antigen BJ-HCC-5;
GN   Name=TPTE;
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
DR   GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR   GO; GO:0035335; P:peptidyl-tyrosine dephosphorylation; TAS:GOC.
DR   GO; GO:0006470; P:protein dephosphorylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TPX2_HUMAN              Reviewed;         747 AA.
AC   Q9ULW0; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9Y2M1;
DE   RecName: Full=Targeting protein for Xklp2;
DE   AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 2;
DE            Short=DIL-2;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 519;
DE   AltName: Full=Protein fls353;
DE   AltName: Full=Restricted expression proliferation-associated protein 100;
DE            Short=p100;
GN   Name=TPX2; Synonyms=C20orf1, C20orf2, DIL2, HCA519;
DR   GO; GO:0005524; F:ATP binding; TAS:ProtInc.
DR   GO; GO:0005525; F:GTP binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007067; P:mitosis; TAS:ProtInc.
DR   GO; GO:0060236; P:regulation of mitotic spindle organization; ISS:UniProtKB.
//
ID   TR10A_HUMAN             Reviewed;         468 AA.
AC   O00220; A8K5I4; Q53Y72; Q96E62;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 10A;
DE   AltName: Full=Death receptor 4;
DE   AltName: Full=TNF-related apoptosis-inducing ligand receptor 1;
DE            Short=TRAIL receptor 1;
DE            Short=TRAIL-R1;
DE   AltName: CD_antigen=CD261;
DE   Flags: Precursor;
GN   Name=TNFRSF10A; Synonyms=APO2, DR4, TRAILR1;
DR   GuidetoPHARMACOLOGY; 1879; -.
DR   GO; GO:0005035; F:death receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0045569; F:TRAIL binding; NAS:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TR10B_HUMAN             Reviewed;         440 AA.
AC   O14763; O14720; O15508; O15517; O15531; Q6UXM8; Q7Z360; Q9BVE0;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 10B;
DE   AltName: Full=Death receptor 5;
DE   AltName: Full=TNF-related apoptosis-inducing ligand receptor 2;
DE            Short=TRAIL receptor 2;
DE            Short=TRAIL-R2;
DE   AltName: CD_antigen=CD262;
DE   Flags: Precursor;
GN   Name=TNFRSF10B; Synonyms=DR5, KILLER, TRAILR2, TRICK2, ZTNFR9;
GN   ORFNames=UNQ160/PRO186;
DR   GuidetoPHARMACOLOGY; 1880; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0045569; F:TRAIL binding; NAS:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; NAS:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; NAS:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
//
ID   TR10C_HUMAN             Reviewed;         259 AA.
AC   O14798; O14755; Q08AS6; Q6FH98; Q6UXM5;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 10C;
DE   AltName: Full=Antagonist decoy receptor for TRAIL/Apo-2L;
DE   AltName: Full=Decoy TRAIL receptor without death domain;
DE   AltName: Full=Decoy receptor 1;
DE            Short=DcR1;
DE   AltName: Full=Lymphocyte inhibitor of TRAIL;
DE   AltName: Full=TNF-related apoptosis-inducing ligand receptor 3;
DE            Short=TRAIL receptor 3;
DE            Short=TRAIL-R3;
DE   AltName: Full=TRAIL receptor without an intracellular domain;
DE   AltName: CD_antigen=CD263;
DE   Flags: Precursor;
GN   Name=TNFRSF10C; Synonyms=DCR1, LIT, TRAILR3, TRID;
GN   ORFNames=UNQ321/PRO366;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TR10D_HUMAN             Reviewed;         386 AA.
AC   Q9UBN6; B2R8W0; Q9Y6Q4;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 10D;
DE   AltName: Full=Decoy receptor 2;
DE            Short=DcR2;
DE   AltName: Full=TNF-related apoptosis-inducing ligand receptor 4;
DE            Short=TRAIL receptor 4;
DE            Short=TRAIL-R4;
DE   AltName: Full=TRAIL receptor with a truncated death domain;
DE   AltName: CD_antigen=CD264;
DE   Flags: Precursor;
GN   Name=TNFRSF10D; Synonyms=DCR2, TRAILR4, TRUNDD;
GN   ORFNames=UNQ251/PRO288;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TR112_HUMAN             Reviewed;         125 AA.
AC   Q9UI30; B2R539; J3KNG5; Q3MHC7; Q8N2Z4;
DE   RecName: Full=tRNA methyltransferase 112 homolog;
DE   AltName: Full=TRM112-like protein;
GN   Name=TRMT112; ORFNames=AD-001, HSPC152, HSPC170;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008276; F:protein methyltransferase activity; IDA:MGI.
DR   GO; GO:0018364; P:peptidyl-glutamine methylation; IDA:UniProtKB.
//
ID   TR11B_HUMAN             Reviewed;         401 AA.
AC   O00300; B2R9A8; O60236; Q53FX6; Q9UHP4;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 11B;
DE   AltName: Full=Osteoclastogenesis inhibitory factor;
DE   AltName: Full=Osteoprotegerin;
DE   Flags: Precursor;
GN   Name=TNFRSF11B; Synonyms=OCIF, OPG;
DR   GO; GO:0005125; F:cytokine activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0045779; P:negative regulation of bone resorption; IEA:Ensembl.
DR   GO; GO:0042489; P:negative regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0046685; P:response to arsenic-containing substance; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0032026; P:response to magnesium ion; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
//
ID   TR13B_HUMAN             Reviewed;         293 AA.
AC   O14836; B2R8B0; B7Z6V8; Q32LX4; Q7Z6F5;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 13B;
DE   AltName: Full=Transmembrane activator and CAML interactor;
DE   AltName: CD_antigen=CD267;
GN   Name=TNFRSF13B; Synonyms=TACI;
DR   GuidetoPHARMACOLOGY; 1885; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0030889; P:negative regulation of B cell proliferation; IEA:Ensembl.
//
ID   TR13C_HUMAN             Reviewed;         184 AA.
AC   Q96RJ3;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 13C;
DE   AltName: Full=B-cell-activating factor receptor;
DE   AltName: Full=BAFF receptor;
DE            Short=BAFF-R;
DE   AltName: Full=BLyS receptor 3;
DE   AltName: CD_antigen=CD268;
GN   Name=TNFRSF13C; Synonyms=BAFFR, BR3;
DR   GuidetoPHARMACOLOGY; 1886; -.
DR   GO; GO:0031296; P:B cell costimulation; IEA:Ensembl.
DR   GO; GO:0001782; P:B cell homeostasis; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0002636; P:positive regulation of germinal center formation; IEA:Ensembl.
DR   GO; GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; IEA:Ensembl.
//
ID   TR150_HUMAN             Reviewed;         955 AA.
AC   Q9Y2W1; D3DPS5; Q5VTK6;
DE   RecName: Full=Thyroid hormone receptor-associated protein 3;
DE   AltName: Full=Thyroid hormone receptor-associated protein complex 150 kDa component;
DE            Short=Trap150;
GN   Name=THRAP3; Synonyms=TRAP150;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:MGI.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0042809; F:vitamin D receptor binding; NAS:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030518; P:intracellular steroid hormone receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0048255; P:mRNA stabilization; IMP:UniProtKB.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   TR16L_HUMAN             Reviewed;         348 AA.
AC   Q309B1; A0PK10; B2RUW6; B4DQK2; B4DWQ8;
DE   RecName: Full=Tripartite motif-containing protein 16-like protein;
DE   AltName: Full=Tripartite motif-containing protein 70;
GN   Name=TRIM16L; Synonyms=TRIM70;
//
ID   TR19L_HUMAN             Reviewed;         430 AA.
AC   Q969Z4; Q86V34; Q96JU1; Q9BUX7;
DE   RecName: Full=Tumor necrosis factor receptor superfamily member 19L;
DE   AltName: Full=Receptor expressed in lymphoid tissues;
DE   Flags: Precursor;
GN   Name=RELT; Synonyms=TNFRSF19L;
//
ID   TR1L1_HUMAN             Reviewed;         369 AA.
AC   Q8N609; Q8N2L7;
DE   RecName: Full=Translocating chain-associated membrane protein 1-like 1;
GN   Name=TRAM1L1;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TR3N_HUMAN              Reviewed;         133 AA.
AC   Q6F5E7;
DE   RecName: Full=Protein TXNRD3NB;
DE   AltName: Full=Thioredoxin reductase 2 intronic transcript 1;
DE   AltName: Full=Thioredoxin reductase 3 intronic transcript 1;
DE   AltName: Full=Thioredoxin reductase 3 neighbor gene protein;
DE            Short=TXNRD3 neighbor gene protein;
DE   AltName: Full=Thioredoxin reductase 3 new transcript 1;
GN   Name=TXNRD3NB; Synonyms=TR2IT1, TXNRD3IT1, TXNRD3NT1;
//
ID   TR43B_HUMAN             Reviewed;         446 AA.
AC   A6NCK2;
DE   RecName: Full=Tripartite motif-containing protein 43B;
GN   Name=TRIM43B;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TR49B_HUMAN             Reviewed;         452 AA.
AC   A6NDI0;
DE   RecName: Full=Putative tripartite motif-containing protein 49B;
DE   AltName: Full=RING finger protein 18B;
GN   Name=TRIM49B; Synonyms=RNF18B;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TR49C_HUMAN             Reviewed;         452 AA.
AC   P0CI26; A0AVR7; A0AVR9; Q6DJV1; Q9NS80;
DE   RecName: Full=Tripartite motif-containing protein 49C;
DE   AltName: Full=Tripartite motif-containing protein 49-like protein 2;
GN   Name=TRIM49C; Synonyms=TRIM49L2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TR61B_HUMAN             Reviewed;         477 AA.
AC   Q9BVS5; Q9H0Q9; Q9NWS7;
DE   RecName: Full=tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial;
DE            EC=2.1.1.220;
DE   Flags: Precursor;
GN   Name=TRMT61B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016429; F:tRNA (adenine-N1-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0070901; P:mitochondrial tRNA methylation; IDA:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
//
ID   TR64B_HUMAN             Reviewed;         449 AA.
AC   A6NI03;
DE   RecName: Full=Putative tripartite motif-containing protein 64B;
GN   Name=TRIM64B;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TR5OS_HUMAN             Reviewed;         111 AA.
AC   A6NMA1;
DE   RecName: Full=Putative uncharacterized protein TRPC5OS;
DE   AltName: Full=TRPC5 opposite strand protein;
DE   AltName: Full=TRPC5-antisense RNA 1;
GN   Name=TRPC5OS; Synonyms=TRPC5-AS1;
//
ID   TR64C_HUMAN             Reviewed;         447 AA.
AC   A6NLI5;
DE   RecName: Full=Putative tripartite motif-containing protein 64C;
GN   Name=TRIM64C;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRA2A_HUMAN             Reviewed;         282 AA.
AC   Q13595;
DE   RecName: Full=Transformer-2 protein homolog alpha;
DE            Short=TRA-2 alpha;
DE            Short=TRA2-alpha;
DE   AltName: Full=Transformer-2 protein homolog A;
GN   Name=TRA2A;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
//
ID   TRA2B_HUMAN             Reviewed;         288 AA.
AC   P62995; B4DVK2; D3DNU3; O15449; Q15815; Q64283;
DE   RecName: Full=Transformer-2 protein homolog beta;
DE            Short=TRA-2 beta;
DE            Short=TRA2-beta;
DE            Short=hTRA2-beta;
DE   AltName: Full=Splicing factor, arginine/serine-rich 10;
DE   AltName: Full=Transformer-2 protein homolog B;
GN   Name=TRA2B; Synonyms=SFRS10;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0048026; P:positive regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
//
ID   TRABD_HUMAN             Reviewed;         376 AA.
AC   Q9H4I3; Q19CC5; Q96ED8; Q9H7N1; Q9UGX6; Q9UGX7;
DE   RecName: Full=TraB domain-containing protein;
DE   AltName: Full=Protein TTG2;
GN   Name=TRABD; Synonyms=TTG2; ORFNames=PP2447;
//
ID   TRAD1_HUMAN             Reviewed;         582 AA.
AC   O14545; A8K5L6;
DE   RecName: Full=TRAF-type zinc finger domain-containing protein 1;
DE   AltName: Full=Protein FLN29;
GN   Name=TRAFD1; Synonyms=FLN29;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045824; P:negative regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
//
ID   TRADD_HUMAN             Reviewed;         312 AA.
AC   Q15628; B2RDS3; Q52NZ1;
DE   RecName: Full=Tumor necrosis factor receptor type 1-associated DEATH domain protein;
DE            Short=TNFR1-associated DEATH domain protein;
DE   AltName: Full=TNFRSF1A-associated via death domain;
GN   Name=TRADD;
DR   GO; GO:0060090; F:binding, bridging; IPI:BHF-UCL.
DR   GO; GO:0070513; F:death domain binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019900; F:kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:InterPro.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; TAS:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0051798; P:positive regulation of hair follicle development; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; TAS:BHF-UCL.
//
ID   TRAF1_HUMAN             Reviewed;         416 AA.
AC   Q13077; B4DJ77; Q658U1; Q8NF13;
DE   RecName: Full=TNF receptor-associated factor 1;
DE   AltName: Full=Epstein-Barr virus-induced protein 6;
GN   Name=TRAF1; Synonyms=EBI6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:2001236; P:regulation of extrinsic apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   TRAF2_HUMAN             Reviewed;         501 AA.
AC   Q12933; A8K107; B4DPJ7; Q7Z337; Q96NT2;
DE   RecName: Full=TNF receptor-associated factor 2;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ubiquitin-protein ligase TRAF2;
DE   AltName: Full=Tumor necrosis factor type 2 receptor-associated protein 3;
GN   Name=TRAF2; Synonyms=TRAP3;
DR   GO; GO:0005174; F:CD40 receptor binding; ISS:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; NAS:ProtInc.
DR   GO; GO:0046625; F:sphingolipid binding; IDA:UniProtKB.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; TAS:Reactome.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0043623; P:cellular protein complex assembly; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0034351; P:negative regulation of glial cell apoptotic process; IEA:Ensembl.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0090073; P:positive regulation of protein homodimerization activity; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IPI:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:2001239; P:regulation of extrinsic apoptotic signaling pathway in absence of ligand; TAS:Reactome.
DR   GO; GO:0051023; P:regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:UniProtKB.
//
ID   TRAF3_HUMAN             Reviewed;         568 AA.
AC   Q13114; B7Z8C4; Q12990; Q13076; Q13947; Q6AZX1; Q9UNL1;
DE   RecName: Full=TNF receptor-associated factor 3;
DE            EC=6.3.2.-;
DE   AltName: Full=CAP-1;
DE   AltName: Full=CD40 receptor-associated factor 1;
DE            Short=CRAF1;
DE   AltName: Full=CD40-binding protein;
DE            Short=CD40BP;
DE   AltName: Full=LMP1-associated protein 1;
DE            Short=LAP1;
GN   Name=TRAF3; Synonyms=CAP1, CRAF1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0001817; P:regulation of cytokine production; ISS:UniProtKB.
DR   GO; GO:0050688; P:regulation of defense response to virus; ISS:UniProtKB.
DR   GO; GO:0032648; P:regulation of interferon-beta production; ISS:UniProtKB.
DR   GO; GO:0030162; P:regulation of proteolysis; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
//
ID   TRAF4_HUMAN             Reviewed;         470 AA.
AC   Q9BUZ4; O75615; Q14848; Q2KJU4; Q2PJN8;
DE   RecName: Full=TNF receptor-associated factor 4;
DE   AltName: Full=Cysteine-rich domain associated with RING and Traf domains protein 1;
DE   AltName: Full=Metastatic lymph node gene 62 protein;
DE            Short=MLN 62;
DE   AltName: Full=RING finger protein 83;
GN   Name=TRAF4; Synonyms=CART1, MLN62, RNF83;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0090073; P:positive regulation of protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0007585; P:respiratory gaseous exchange; IEA:Ensembl.
DR   GO; GO:0030323; P:respiratory tube development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TRAF5_HUMAN             Reviewed;         557 AA.
AC   O00463; Q6FHY1;
DE   RecName: Full=TNF receptor-associated factor 5;
DE   AltName: Full=RING finger protein 84;
GN   Name=TRAF5; Synonyms=RNF84;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IEA:Ensembl.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IEP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TRAF6_HUMAN             Reviewed;         522 AA.
AC   Q9Y4K3; A6NKI7; A8KAB3; D3DR16; Q8NEH5;
DE   RecName: Full=TNF receptor-associated factor 6;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ubiquitin-protein ligase TRAF6;
DE   AltName: Full=Interleukin-1 signal transducer;
DE   AltName: Full=RING finger protein 85;
GN   Name=TRAF6; Synonyms=RNF85;
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043422; F:protein kinase B binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0031996; F:thioesterase binding; IPI:UniProtKB.
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IDA:MGI.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IEA:Ensembl.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0045453; P:bone resorption; IEA:Ensembl.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:MGI.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0030316; P:osteoclast differentiation; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0045084; P:positive regulation of interleukin-12 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.
DR   GO; GO:0045410; P:positive regulation of interleukin-6 biosynthetic process; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.
DR   GO; GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; NAS:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0051023; P:regulation of immunoglobulin secretion; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IDA:UniProtKB.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0042088; P:T-helper 1 type immune response; IEA:Ensembl.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
//
ID   TRAF7_HUMAN             Reviewed;         670 AA.
AC   Q6Q0C0; Q9H073;
DE   RecName: Full=E3 ubiquitin-protein ligase TRAF7;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger and WD repeat-containing protein 1;
DE   AltName: Full=RING finger protein 119;
DE   AltName: Full=TNF receptor-associated factor 7;
GN   Name=TRAF7; Synonyms=RFWD1, RNF119;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0000185; P:activation of MAPKKK activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IDA:MGI.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TRAIP_HUMAN             Reviewed;         469 AA.
AC   Q9BWF2; B5BU84; B5BUL3; O00467;
DE   RecName: Full=E3 ubiquitin-protein ligase TRAIP;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 206;
DE   AltName: Full=TRAF-interacting protein;
GN   Name=TRAIP; Synonyms=RNF206, TRIP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005057; F:receptor signaling protein activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TRAK1_HUMAN             Reviewed;         953 AA.
AC   Q9UPV9; E9PDS2; J3KNT7; Q63HR0; Q659B5; Q96B69;
DE   RecName: Full=Trafficking kinesin-binding protein 1;
DE   AltName: Full=106 kDa O-GlcNAc transferase-interacting protein;
GN   Name=TRAK1; Synonyms=KIAA1042, OIP106;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008333; P:endosome to lysosome transport; IDA:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; ISS:UniProtKB.
DR   GO; GO:0006605; P:protein targeting; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
//
ID   TRAK2_HUMAN             Reviewed;         914 AA.
AC   O60296; E7EV21; Q8WVH7; Q96NS2; Q9C0K5; Q9C0K6;
DE   RecName: Full=Trafficking kinesin-binding protein 2;
DE   AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;
GN   Name=TRAK2; Synonyms=ALS2CR3, KIAA0549;
DR   GO; GO:0050811; F:GABA receptor binding; NAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005102; F:receptor binding; ISS:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IEA:Ensembl.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   TRAM1_HUMAN             Reviewed;         374 AA.
AC   Q15629;
DE   RecName: Full=Translocating chain-associated membrane protein 1;
GN   Name=TRAM1; Synonyms=TRAM;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006613; P:cotranslational protein targeting to membrane; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.
DR   GO; GO:0006412; P:translation; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TRAM2_HUMAN             Reviewed;         370 AA.
AC   Q15035; A8K6T6;
DE   RecName: Full=Translocating chain-associated membrane protein 2;
GN   Name=TRAM2; Synonyms=KIAA0057;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032964; P:collagen biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TRAP1_HUMAN             Reviewed;         704 AA.
AC   Q12931; D3DUC8; O43642; O75235; Q9UHL5;
DE   RecName: Full=Heat shock protein 75 kDa, mitochondrial;
DE            Short=HSP 75;
DE   AltName: Full=TNFR-associated protein 1;
DE   AltName: Full=Tumor necrosis factor type 1 receptor-associated protein;
DE            Short=TRAP-1;
DE   Flags: Precursor;
GN   Name=TRAP1; Synonyms=HSP75;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; NAS:UniProtKB.
DR   GO; GO:1901856; P:negative regulation of cellular respiration; IMP:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   GO; GO:0006950; P:response to stress; IEA:InterPro.
//
ID   TRAT1_HUMAN             Reviewed;         186 AA.
AC   Q6PIZ9; Q9NZX5;
DE   RecName: Full=T-cell receptor-associated transmembrane adapter 1;
DE   AltName: Full=T-cell receptor-interacting molecule;
DE            Short=TRIM;
DE   AltName: Full=pp29/30;
GN   Name=TRAT1; Synonyms=TCRIM; ORFNames=HSPC062;
DR   GO; GO:0005068; F:transmembrane receptor protein tyrosine kinase adaptor activity; TAS:ProtInc.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0001920; P:negative regulation of receptor recycling; IDA:MGI.
DR   GO; GO:0051051; P:negative regulation of transport; IDA:MGI.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IDA:MGI.
DR   GO; GO:0050862; P:positive regulation of T cell receptor signaling pathway; IDA:MGI.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TRBC1_HUMAN             Reviewed;         177 AA.
AC   P01850; A0A5B8; A6NH51;
DE   RecName: Full=T-cell receptor beta-1 chain C region;
GN   Name=TRBC1;
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TRBC2_HUMAN             Reviewed;         178 AA.
AC   A0A5B9;
DE   RecName: Full=T-cell receptor beta-2 chain C region;
GN   Name=TRBC2; Synonyms=TCRBC2;
//
ID   TRBM_HUMAN              Reviewed;         575 AA.
AC   P07204; Q8IV29; Q9UC32;
DE   RecName: Full=Thrombomodulin;
DE            Short=TM;
DE   AltName: Full=Fetomodulin;
DE   AltName: CD_antigen=CD141;
DE   Flags: Precursor;
GN   Name=THBD; Synonyms=THRM;
DR   GO; GO:0005509; F:calcium ion binding; TAS:ProtInc.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; TAS:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; TAS:BHF-UCL.
DR   GO; GO:0010544; P:negative regulation of platelet activation; TAS:BHF-UCL.
DR   GO; GO:0051591; P:response to cAMP; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
//
ID   TRBP2_HUMAN             Reviewed;         366 AA.
AC   Q15633; Q12878; Q8WY32; Q8WY33; Q9BRY2;
DE   RecName: Full=RISC-loading complex subunit TARBP2;
DE   AltName: Full=TAR RNA-binding protein 2;
DE   AltName: Full=Trans-activation-responsive RNA-binding protein;
GN   Name=TARBP2; Synonyms=TRBP;
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR   GO; GO:0035198; F:miRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0035197; F:siRNA binding; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035280; P:miRNA loading onto RISC involved in gene silencing by miRNA; IDA:UniProtKB.
DR   GO; GO:0050689; P:negative regulation of defense response to virus by host; IDA:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; TAS:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0031054; P:pre-miRNA processing; IDA:UniProtKB.
DR   GO; GO:0030422; P:production of siRNA involved in RNA interference; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   GO; GO:0046782; P:regulation of viral transcription; IDA:UniProtKB.
DR   GO; GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; IMP:UniProtKB.
//
ID   TRC2L_HUMAN             Reviewed;         142 AA.
AC   Q6ZNB5;
DE   RecName: Full=Putative short transient receptor potential channel 2-like protein;
DE            Short=TrpC2-like protein;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0000012; P:single strand break repair; IEA:InterPro.
//
ID   TRDC_HUMAN              Reviewed;         153 AA.
AC   B7Z8K6;
DE   RecName: Full=T-cell receptor delta chain C region;
GN   Name=TRDC;
//
ID   TRDMT_HUMAN             Reviewed;         391 AA.
AC   O14717; B0YJ02; B0YJ03; B0YJ07; B0YJ08; O43669; Q86WW6;
DE   RecName: Full=tRNA (cytosine(38)-C(5))-methyltransferase;
DE            EC=2.1.1.204;
DE   AltName: Full=DNA (cytosine-5)-methyltransferase-like protein 2;
DE            Short=Dnmt2;
DE   AltName: Full=DNA methyltransferase homolog HsaIIP;
DE            Short=DNA MTase homolog HsaIIP;
DE            Short=M.HsaIIP;
DE   AltName: Full=PuMet;
GN   Name=TRDMT1; Synonyms=DNMT2;
DR   GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; TAS:ProtInc.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008175; F:tRNA methyltransferase activity; IDA:MGI.
DR   GO; GO:0090116; P:C-5 methylation of cytosine; TAS:GOC.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0030488; P:tRNA methylation; IDA:MGI.
//
ID   TRDN_HUMAN              Reviewed;         729 AA.
AC   Q13061; A5D6W5; F5H2W7; Q6NSB8;
DE   RecName: Full=Triadin;
GN   Name=TRDN;
DR   GO; GO:0044325; F:ion channel binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0030674; F:protein binding, bridging; ISS:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; ISS:BHF-UCL.
DR   GO; GO:0090158; P:endoplasmic reticulum membrane organization; ISS:BHF-UCL.
DR   GO; GO:0060047; P:heart contraction; IMP:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0014902; P:myotube differentiation; IEA:Ensembl.
DR   GO; GO:0060315; P:negative regulation of ryanodine-sensitive calcium-release channel activity; TAS:BHF-UCL.
DR   GO; GO:1901846; P:positive regulation of cell communication by electrical coupling involved in cardiac conduction; ISS:BHF-UCL.
DR   GO; GO:0060316; P:positive regulation of ryanodine-sensitive calcium-release channel activity; ISS:BHF-UCL.
DR   GO; GO:0086036; P:regulation of cardiac muscle cell membrane potential; ISS:BHF-UCL.
DR   GO; GO:0010649; P:regulation of cell communication by electrical coupling; TAS:BHF-UCL.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; TAS:BHF-UCL.
DR   GO; GO:0010880; P:regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:BHF-UCL.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; ISS:BHF-UCL.
DR   GO; GO:0014070; P:response to organic cyclic compound; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TREA_HUMAN              Reviewed;         583 AA.
AC   O43280; Q32MB9; Q53FY8;
DE   RecName: Full=Trehalase;
DE            EC=3.2.1.28;
DE   AltName: Full=Alpha,alpha-trehalase;
DE   AltName: Full=Alpha,alpha-trehalose glucohydrolase;
DE   Flags: Precursor;
GN   Name=TREH; Synonyms=TREA;
DR   GO; GO:0004555; F:alpha,alpha-trehalase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0044245; P:polysaccharide digestion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0005993; P:trehalose catabolic process; TAS:ProtInc.
DR   GO; GO:0005991; P:trehalose metabolic process; NAS:UniProtKB.
//
ID   TREF1_HUMAN             Reviewed;        1200 AA.
AC   Q96PN7; Q05GC6; Q7Z6T2; Q7Z6T3; Q9NQ72; Q9NQ73; Q9NUN9;
DE   RecName: Full=Transcriptional-regulating factor 1;
DE   AltName: Full=Breast cancer anti-estrogen resistance 2;
DE   AltName: Full=Transcriptional-regulating protein 132;
DE   AltName: Full=Zinc finger protein rapa;
DE   AltName: Full=Zinc finger transcription factor TReP-132;
GN   Name=TRERF1; Synonyms=BCAR2, RAPA, TREP132;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0008301; F:DNA binding, bending; NAS:UniProtKB.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001104; F:RNA polymerase II transcription cofactor activity; NAS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0006707; P:cholesterol catabolic process; NAS:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0046885; P:regulation of hormone biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:GOC.
DR   GO; GO:0006694; P:steroid biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; NAS:GOC.
//
ID   TREM1_HUMAN             Reviewed;         234 AA.
AC   Q9NP99; B4DWG2; K7EJW1; Q53FL8; Q5T2C9; Q86YU1;
DE   RecName: Full=Triggering receptor expressed on myeloid cells 1;
DE            Short=TREM-1;
DE   AltName: Full=Triggering receptor expressed on monocytes 1;
DE   AltName: CD_antigen=CD354;
DE   Flags: Precursor;
GN   Name=TREM1;
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
//
ID   TREM2_HUMAN             Reviewed;         230 AA.
AC   Q9NZC2; Q8N5H8; Q8WYN6;
DE   RecName: Full=Triggering receptor expressed on myeloid cells 2;
DE            Short=TREM-2;
DE   AltName: Full=Triggering receptor expressed on monocytes 2;
DE   Flags: Precursor;
GN   Name=TREM2;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IEA:Ensembl.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   TREX1_HUMAN             Reviewed;         369 AA.
AC   Q9NSU2; B2RCN9; Q8TEU2; Q9BPW1; Q9Y4X2;
DE   RecName: Full=Three-prime repair exonuclease 1;
DE            EC=3.1.11.2;
DE   AltName: Full=3'-5' exonuclease TREX1;
DE   AltName: Full=DNase III;
GN   Name=TREX1;
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0008296; F:3'-5'-exodeoxyribonuclease activity; ISS:UniProtKB.
DR   GO; GO:0032558; F:adenyl deoxyribonucleotide binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0008853; F:exodeoxyribonuclease III activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0032405; F:MutLalpha complex binding; IDA:MGI.
DR   GO; GO:0032407; F:MutSalpha complex binding; IDA:MGI.
DR   GO; GO:0042803; F:protein homodimerization activity; NAS:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0035458; P:cellular response to interferon-beta; IEA:Ensembl.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; ISS:GOC.
DR   GO; GO:0006259; P:DNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; NAS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006298; P:mismatch repair; NAS:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
//
ID   TREX2_HUMAN             Reviewed;         279 AA.
AC   Q9BQ50; Q45F08; Q9UN77;
DE   RecName: Full=Three prime repair exonuclease 2;
DE            EC=3.1.11.2;
DE   AltName: Full=3'-5' exonuclease TREX2;
GN   Name=TREX2;
DR   GO; GO:0008296; F:3'-5'-exodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0008853; F:exodeoxyribonuclease III activity; IEA:UniProtKB-EC.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:GOC.
DR   GO; GO:0006259; P:DNA metabolic process; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
//
ID   TRFE_HUMAN              Reviewed;         698 AA.
AC   P02787; O43890; Q1HBA5; Q9NQB8; Q9UHV0;
DE   RecName: Full=Serotransferrin;
DE            Short=Transferrin;
DE   AltName: Full=Beta-1 metal-binding globulin;
DE   AltName: Full=Siderophilin;
DE   Flags: Precursor;
GN   Name=TF; ORFNames=PRO1400;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRFL_HUMAN              Reviewed;         710 AA.
AC   P02788; A8K9U8; B2MV13; B7Z4X2; E7EQH5; O00756; Q16780; Q16785;
AC   Q16786; Q16789; Q5DSM0; Q8IU92; Q8IZH6; Q8TCD2; Q96KZ4; Q96KZ5;
AC   Q9H1Z3; Q9UCY5;
DE   RecName: Full=Lactotransferrin;
DE            Short=Lactoferrin;
DE            EC=3.4.21.-;
DE   AltName: Full=Growth-inhibiting protein 12;
DE   AltName: Full=Talalactoferrin;
DE   Contains:
DE     RecName: Full=Lactoferricin-H;
DE              Short=Lfcin-H;
DE   Contains:
DE     RecName: Full=Kaliocin-1;
DE   Contains:
DE     RecName: Full=Lactoferroxin-A;
DE   Contains:
DE     RecName: Full=Lactoferroxin-B;
DE   Contains:
DE     RecName: Full=Lactoferroxin-C;
DE   Flags: Precursor;
GN   Name=LTF; Synonyms=GIG12, LF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0008233; F:peptidase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IDA:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0019731; P:antibacterial humoral response; IDA:UniProtKB.
DR   GO; GO:0019732; P:antifungal humoral response; IDA:UniProtKB.
DR   GO; GO:0060349; P:bone morphogenesis; IDA:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:InterPro.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0002227; P:innate immune response in mucosa; IDA:UniProtKB.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0033214; P:iron assimilation by chelation and transport; TAS:Reactome.
DR   GO; GO:0006826; P:iron ion transport; IEA:InterPro.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:2001205; P:negative regulation of osteoclast development; ISS:UniProtKB.
DR   GO; GO:1900229; P:negative regulation of single-species biofilm formation in or on host organism; IDA:UniProtKB.
DR   GO; GO:2000308; P:negative regulation of tumor necrosis factor (ligand) superfamily member 11 production; ISS:UniProtKB.
DR   GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:1900159; P:positive regulation of bone mineralization involved in bone maturation; ISS:UniProtKB.
DR   GO; GO:1902732; P:positive regulation of chondrocyte proliferation; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0033690; P:positive regulation of osteoblast proliferation; IDA:UniProtKB.
DR   GO; GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0034145; P:positive regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0001817; P:regulation of cytokine production; IDA:UniProtKB.
DR   GO; GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0052572; P:response to host immune response; TAS:Reactome.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TRFM_HUMAN              Reviewed;         738 AA.
AC   P08582; Q9BQE2;
DE   RecName: Full=Melanotransferrin;
DE   AltName: Full=Melanoma-associated antigen p97;
DE   AltName: CD_antigen=CD228;
DE   Flags: Precursor;
GN   Name=MFI2; Synonyms=MAP97;
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IMP:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:InterPro.
DR   GO; GO:0097286; P:iron ion import; IMP:UniProt.
DR   GO; GO:1900025; P:negative regulation of substrate adhesion-dependent cell spreading; IDA:UniProt.
DR   GO; GO:0090091; P:positive regulation of extracellular matrix disassembly; IDA:UniProt.
DR   GO; GO:0010756; P:positive regulation of plasminogen activation; IDA:UniProt.
//
ID   TRFR_HUMAN              Reviewed;         398 AA.
AC   P34981; Q2M339;
DE   RecName: Full=Thyrotropin-releasing hormone receptor;
DE            Short=TRH-R;
DE   AltName: Full=Thyroliberin receptor;
GN   Name=TRHR;
DR   GuidetoPHARMACOLOGY; 363; -.
DR   GO; GO:0004997; F:thyrotropin-releasing hormone receptor activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   TRGC1_HUMAN             Reviewed;         173 AA.
AC   P0CF51;
DE   RecName: Full=T-cell receptor gamma chain C region 1;
GN   Name=TRGC1;
//
ID   TRGC2_HUMAN             Reviewed;         189 AA.
AC   P03986;
DE   RecName: Full=T-cell receptor gamma-2 chain C region;
DE   AltName: Full=T-cell receptor gamma chain C region PT-gamma-1/2;
GN   Name=TRGC2; Synonyms=TCRGC2;
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:GOC.
//
ID   TRHDE_HUMAN             Reviewed;        1024 AA.
AC   Q9UKU6; A5PL19; Q6UWJ4;
DE   RecName: Full=Thyrotropin-releasing hormone-degrading ectoenzyme;
DE            Short=TRH-DE;
DE            Short=TRH-degrading ectoenzyme;
DE            EC=3.4.19.6;
DE   AltName: Full=Pyroglutamyl-peptidase II;
DE            Short=PAP-II;
DE   AltName: Full=TRH-specific aminopeptidase;
DE   AltName: Full=Thyroliberinase;
GN   Name=TRHDE; ORFNames=UNQ2507/PRO5995;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TRHY_HUMAN              Reviewed;        1943 AA.
AC   Q07283; Q5VUI3;
DE   RecName: Full=Trichohyalin;
GN   Name=TCHH; Synonyms=THH, THL, TRHY;
DR   GO; GO:0005509; F:calcium ion binding; TAS:UniProtKB.
DR   GO; GO:0031424; P:keratinization; IEA:UniProtKB-KW.
//
ID   TRH_HUMAN               Reviewed;         242 AA.
AC   P20396; B2R8R1; Q2TB83;
DE   RecName: Full=Pro-thyrotropin-releasing hormone;
DE            Short=Pro-TRH;
DE   AltName: Full=Prothyroliberin;
DE   Contains:
DE     RecName: Full=Thyrotropin-releasing hormone;
DE              Short=TRH;
DE     AltName: Full=Protirelin;
DE     AltName: Full=TSH-releasing factor;
DE     AltName: Full=Thyroliberin;
DE     AltName: Full=Thyrotropin-releasing factor;
DE              Short=TRF;
DE   Flags: Precursor;
GN   Name=TRH;
DR   GO; GO:0008437; F:thyrotropin-releasing hormone activity; TAS:ProtInc.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0001692; P:histamine metabolic process; IEA:Ensembl.
DR   GO; GO:0009755; P:hormone-mediated signaling pathway; IEA:InterPro.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0014050; P:negative regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0014054; P:positive regulation of gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TRI10_HUMAN             Reviewed;         481 AA.
AC   Q9UDY6; A6NF84; Q5SRJ5; Q5SRK8; Q86Z08; Q96QB6; Q9C023; Q9C024;
DE   RecName: Full=Tripartite motif-containing protein 10;
DE   AltName: Full=B30-RING finger protein;
DE   AltName: Full=RING finger protein 9;
GN   Name=TRIM10; Synonyms=RFB30, RNF9;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
//
ID   TRI11_HUMAN             Reviewed;         468 AA.
AC   Q96F44; A6NKE2; B2RB82; B3KUS3; B4DX88; Q5VSU1; Q8NCA6; Q9C022;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM11;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein BIA1;
DE   AltName: Full=RING finger protein 92;
DE   AltName: Full=Tripartite motif-containing protein 11;
GN   Name=TRIM11; Synonyms=RNF92;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProt.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IMP:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0046598; P:positive regulation of viral entry into host cell; IMP:UniProt.
//
ID   TRI13_HUMAN             Reviewed;         407 AA.
AC   O60858; B2RB49; Q5UBW0; Q5W0U8; Q5W0U9; Q9BQ47; Q9C021;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM13;
DE            EC=6.3.2.-;
DE   AltName: Full=B-cell chronic lymphocytic leukemia tumor suppressor Leu5;
DE   AltName: Full=Leukemia-associated protein 5;
DE   AltName: Full=Putative tumor suppressor RFP2;
DE   AltName: Full=RING finger protein 77;
DE   AltName: Full=Ret finger protein 2;
DE   AltName: Full=Tripartite motif-containing protein 13;
GN   Name=TRIM13; Synonyms=LEU5, RFP2, RNF77;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0010942; P:positive regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProt.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0010332; P:response to gamma radiation; IEP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TRI14_HUMAN             Reviewed;         442 AA.
AC   Q14142; A8K9W0; E7EQC4; F8W956; Q548W9; Q5TBQ8; Q6ZWL7; Q9BRD8;
AC   Q9C020;
DE   RecName: Full=Tripartite motif-containing protein 14;
GN   Name=TRIM14; Synonyms=KIAA0129;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
//
ID   TRI15_HUMAN             Reviewed;         465 AA.
AC   Q9C019; A2BEC9; O95604; Q8IUX9; Q9C018;
DE   RecName: Full=Tripartite motif-containing protein 15;
DE   AltName: Full=RING finger protein 93;
DE   AltName: Full=Zinc finger protein 178;
DE   AltName: Full=Zinc finger protein B7;
GN   Name=TRIM15; Synonyms=RNF93, ZNF178, ZNFB7;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProt.
DR   GO; GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.
DR   GO; GO:1901253; P:negative regulation of intracellular transport of viral material; IMP:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProt.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; IMP:UniProt.
//
ID   TRI16_HUMAN             Reviewed;         564 AA.
AC   O95361; Q6IAL8; Q7Z6I2; Q96BE8; Q96J43;
DE   RecName: Full=Tripartite motif-containing protein 16;
DE   AltName: Full=Estrogen-responsive B box protein;
GN   Name=TRIM16; Synonyms=EBBP;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0019966; F:interleukin-1 binding; IPI:UniProtKB.
DR   GO; GO:0032089; F:NACHT domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IMP:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0048386; P:positive regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0060416; P:response to growth hormone; IDA:UniProtKB.
DR   GO; GO:0046683; P:response to organophosphorus; IEP:UniProtKB.
DR   GO; GO:0032526; P:response to retinoic acid; IEP:UniProtKB.
//
ID   TRI17_HUMAN             Reviewed;         477 AA.
AC   Q9Y577; B4DVJ2; Q5VST8;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM17;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 16;
DE   AltName: Full=Testis RING finger protein;
DE   AltName: Full=Tripartite motif-containing protein 17;
GN   Name=TRIM17; Synonyms=RBCC, RNF16, TERF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
//
ID   TRI18_HUMAN             Reviewed;         667 AA.
AC   O15344; B2RCG2; O75361; Q9BZX5;
DE   RecName: Full=E3 ubiquitin-protein ligase Midline-1;
DE            EC=6.3.2.-;
DE   AltName: Full=Midin;
DE   AltName: Full=Putative transcription factor XPRF;
DE   AltName: Full=RING finger protein 59;
DE   AltName: Full=RING finger protein Midline-1;
DE   AltName: Full=Tripartite motif-containing protein 18;
GN   Name=MID1; Synonyms=FXY, RNF59, TRIM18, XPRF;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IMP:UniProt.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProt.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0007389; P:pattern specification process; TAS:ProtInc.
DR   GO; GO:0032874; P:positive regulation of stress-activated MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0035372; P:protein localization to microtubule; IMP:UniProt.
//
ID   TRI22_HUMAN             Reviewed;         498 AA.
AC   Q8IYM9; Q05CQ0; Q15521;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM22;
DE            EC=6.3.2.-;
DE   AltName: Full=50 kDa-stimulated trans-acting factor;
DE   AltName: Full=RING finger protein 94;
DE   AltName: Full=Staf-50;
DE   AltName: Full=Tripartite motif-containing protein 22;
GN   Name=TRIM22; Synonyms=RNF94, STAF50;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0009615; P:response to virus; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TRI23_HUMAN             Reviewed;         574 AA.
AC   P36406; Q9BZY4; Q9BZY5;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM23;
DE            EC=6.3.2.-;
DE   AltName: Full=ADP-ribosylation factor domain-containing protein 1;
DE   AltName: Full=GTP-binding protein ARD-1;
DE   AltName: Full=RING finger protein 46;
DE   AltName: Full=Tripartite motif-containing protein 23;
GN   Name=TRIM23; Synonyms=ARD1, ARFD1, RNF46;
DR   GO; GO:0008047; F:enzyme activator activity; TAS:ProtInc.
DR   GO; GO:0019003; F:GDP binding; IDA:HGNC.
DR   GO; GO:0005525; F:GTP binding; IDA:HGNC.
DR   GO; GO:0003924; F:GTPase activity; IDA:HGNC.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006184; P:GTP catabolic process; IDA:GOC.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:HGNC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TRI25_HUMAN             Reviewed;         630 AA.
AC   Q14258;
DE   RecName: Full=E3 ubiquitin/ISG15 ligase TRIM25;
DE            EC=6.3.2.19;
DE            EC=6.3.2.n3;
DE   AltName: Full=Estrogen-responsive finger protein;
DE   AltName: Full=RING finger protein 147;
DE   AltName: Full=Tripartite motif-containing protein 25;
DE   AltName: Full=Ubiquitin/ISG15-conjugating enzyme TRIM25;
DE   AltName: Full=Zinc finger protein 147;
GN   Name=TRIM25; Synonyms=EFP, RNF147, ZNF147;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProt.
DR   GO; GO:0046596; P:regulation of viral entry into host cell; IDA:UniProt.
DR   GO; GO:1902186; P:regulation of viral release from host cell; IMP:UniProt.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0033280; P:response to vitamin D; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TRI26_HUMAN             Reviewed;         539 AA.
AC   Q12899; A6NG96; Q5SRL2;
DE   RecName: Full=Tripartite motif-containing protein 26;
DE   AltName: Full=Acid finger protein;
DE            Short=AFP;
DE   AltName: Full=RING finger protein 95;
DE   AltName: Full=Zinc finger protein 173;
GN   Name=TRIM26; Synonyms=RNF95, ZNF173;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
//
ID   TRI27_HUMAN             Reviewed;         513 AA.
AC   P14373; A2BE15; Q5RJA8; Q5ST26; Q6LA73; Q6NXR9; Q9BZY6; Q9UJL3;
DE   RecName: Full=Zinc finger protein RFP;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 76;
DE   AltName: Full=Ret finger protein;
DE   AltName: Full=Tripartite motif-containing protein 27;
GN   Name=TRIM27; Synonyms=RFP, RNF76;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; TAS:ProtInc.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0072643; P:interferon-gamma secretion; IMP:UniProtKB.
DR   GO; GO:0002820; P:negative regulation of adaptive immune response; IMP:UniProtKB.
DR   GO; GO:0090281; P:negative regulation of calcium ion import; IMP:UniProtKB.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:MGI.
DR   GO; GO:1900041; P:negative regulation of interleukin-2 secretion; IMP:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:GOC.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TRI29_HUMAN             Reviewed;         588 AA.
AC   Q14134; Q96AA9; Q9BZY7;
DE   RecName: Full=Tripartite motif-containing protein 29;
DE   AltName: Full=Ataxia telangiectasia group D-associated protein;
GN   Name=TRIM29; Synonyms=ATDC;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:1900181; P:negative regulation of protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TRI31_HUMAN             Reviewed;         425 AA.
AC   Q9BZY9; A6NLX6; A9R9Q4; Q53H52; Q5RI37; Q5SRJ7; Q5SRJ8; Q5SS28;
AC   Q96AK4; Q96AP8; Q99579; Q9BZY8;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM31;
DE            EC=6.3.2.-;
DE   AltName: Full=Tripartite motif-containing protein 31;
GN   Name=TRIM31; Synonyms=C6orf13, RNF;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProt.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IMP:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProt.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:1902186; P:regulation of viral release from host cell; IMP:UniProt.
//
ID   TRI32_HUMAN             Reviewed;         653 AA.
AC   Q13049; Q9NQP8;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM32;
DE            EC=6.3.2.-;
DE   AltName: Full=72 kDa Tat-interacting protein;
DE   AltName: Full=Tripartite motif-containing protein 32;
DE   AltName: Full=Zinc finger protein HT2A;
GN   Name=TRIM32; Synonyms=HT2A;
DR   GO; GO:0017022; F:myosin binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:BHF-UCL.
DR   GO; GO:0030957; F:Tat protein binding; TAS:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0031369; F:translation initiation factor binding; ISS:BHF-UCL.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IDA:BHF-UCL.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0045787; P:positive regulation of cell cycle; IDA:BHF-UCL.
DR   GO; GO:0030307; P:positive regulation of cell growth; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:2000147; P:positive regulation of cell motility; ISS:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProt.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; ISS:BHF-UCL.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0045862; P:positive regulation of proteolysis; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0034612; P:response to tumor necrosis factor; ISS:BHF-UCL.
DR   GO; GO:0009411; P:response to UV; ISS:BHF-UCL.
//
ID   TRI33_HUMAN             Reviewed;        1127 AA.
AC   Q9UPN9; O95855; Q5TG72; Q5TG73; Q5TG74; Q9C017; Q9UJ79;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM33;
DE            EC=6.3.2.-;
DE   AltName: Full=Ectodermin homolog;
DE   AltName: Full=RET-fused gene 7 protein;
DE            Short=Protein Rfg7;
DE   AltName: Full=Transcription intermediary factor 1-gamma;
DE            Short=TIF1-gamma;
DE   AltName: Full=Tripartite motif-containing protein 33;
GN   Name=TRIM33; Synonyms=KIAA1113, RFG7, TIF1G;
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:Reactome.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   TRI35_HUMAN             Reviewed;         493 AA.
AC   Q9UPQ4; Q86XQ0; Q8WVA4;
DE   RecName: Full=Tripartite motif-containing protein 35;
DE   AltName: Full=Hemopoietic lineage switch protein 5;
GN   Name=TRIM35; Synonyms=HLS5, KIAA1098;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045930; P:negative regulation of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
//
ID   TRI34_HUMAN             Reviewed;         488 AA.
AC   Q9BYJ4; D3DQS7; Q9C016; Q9HCR0; Q9HCR1; Q9HCR2;
DE   RecName: Full=Tripartite motif-containing protein 34;
DE   AltName: Full=Interferon-responsive finger protein 1;
DE   AltName: Full=RING finger protein 21;
GN   Name=TRIM34; Synonyms=IFP1, RNF21;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
//
ID   TRI36_HUMAN             Reviewed;         728 AA.
AC   Q9NQ86; A1L3Z1; A6NDD0; B7Z3V4; B7ZAV7; E9PFI8; Q0P5Z9;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM36;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 98;
DE   AltName: Full=Tripartite motif-containing protein 36;
DE   AltName: Full=Zinc-binding protein Rbcc728;
GN   Name=TRIM36; Synonyms=RBCC728, RNF98;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007340; P:acrosome reaction; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:InterPro.
//
ID   TRI38_HUMAN             Reviewed;         465 AA.
AC   O00635;
DE   RecName: Full=Tripartite motif-containing protein 38;
DE   AltName: Full=RING finger protein 15;
DE   AltName: Full=Zinc finger protein RoRet;
GN   Name=TRIM38; Synonyms=RNF15, RORET;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IEA:Ensembl.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0046598; P:positive regulation of viral entry into host cell; IDA:UniProt.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IEA:Ensembl.
DR   GO; GO:0032648; P:regulation of interferon-beta production; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TRI39_HUMAN             Reviewed;         518 AA.
AC   Q9HCM9; Q5STG3; Q5STG4; Q76BL3; Q8IYT9; Q96IB6;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM39;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 23;
DE   AltName: Full=Testis-abundant finger protein;
DE   AltName: Full=Tripartite motif-containing protein 39;
GN   Name=TRIM39; Synonyms=RNF23, TFP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:2000059; P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:2001235; P:positive regulation of apoptotic signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   TRI37_HUMAN             Reviewed;         964 AA.
AC   O94972; Q7Z3E6; Q8IYF7; Q8WYF7;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM37;
DE            EC=6.3.2.-;
DE   AltName: Full=Mulibrey nanism protein;
DE   AltName: Full=Tripartite motif-containing protein 37;
GN   Name=TRIM37; Synonyms=KIAA0898, MUL, POB1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070842; P:aggresome assembly; IDA:UniProtKB.
DR   GO; GO:0046600; P:negative regulation of centriole replication; IMP:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
//
ID   TRI40_HUMAN             Reviewed;         258 AA.
AC   Q6P9F5; Q5SRJ6; Q5SS36; Q8TD96;
DE   RecName: Full=Tripartite motif-containing protein 40;
DE   AltName: Full=Probable E3 NEDD8-protein ligase;
DE   AltName: Full=RING finger protein 35;
GN   Name=TRIM40; Synonyms=RNF35;
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:1901223; P:negative regulation of NIK/NF-kappaB signaling; NAS:UniProt.
DR   GO; GO:0042177; P:negative regulation of protein catabolic process; IDA:UniProt.
DR   GO; GO:1900181; P:negative regulation of protein localization to nucleus; IDA:UniProt.
DR   GO; GO:0045116; P:protein neddylation; IDA:UniProt.
//
ID   TRI42_HUMAN             Reviewed;         723 AA.
AC   Q8IWZ5; A1L4B4; Q8N832; Q8NDL3;
DE   RecName: Full=Tripartite motif-containing protein 42;
GN   Name=TRIM42;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI41_HUMAN             Reviewed;         630 AA.
AC   Q8WV44; B3KNJ6; D3DWR9; Q5BKT0; Q7L484; Q96Q10; Q9BSL8;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM41;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger-interacting protein with C kinase;
DE            Short=RINCK;
DE   AltName: Full=Tripartite motif-containing protein 41;
GN   Name=TRIM41; Synonyms=RINCK;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   TRI43_HUMAN             Reviewed;         446 AA.
AC   Q96BQ3; Q53TJ7;
DE   RecName: Full=Tripartite motif-containing protein 43;
GN   Name=TRIM43;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI44_HUMAN             Reviewed;         344 AA.
AC   Q96DX7; D3DR14; Q96QY2; Q9UGK0;
DE   RecName: Full=Tripartite motif-containing protein 44;
DE   AltName: Full=Protein DIPB;
GN   Name=TRIM44; Synonyms=DIPB;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI45_HUMAN             Reviewed;         580 AA.
AC   Q9H8W5; Q53GN0; Q5T2K4; Q5T2K5; Q8IYV6;
DE   RecName: Full=Tripartite motif-containing protein 45;
DE   AltName: Full=RING finger protein 99;
GN   Name=TRIM45; Synonyms=RNF99;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060348; P:bone development; IEA:Ensembl.
//
ID   TRI47_HUMAN             Reviewed;         638 AA.
AC   Q96LD4; Q96GU5; Q9BRN7;
DE   RecName: Full=Tripartite motif-containing protein 47;
DE   AltName: Full=Gene overexpressed in astrocytoma protein;
DE   AltName: Full=RING finger protein 100;
GN   Name=TRIM47; Synonyms=GOA, RNF100;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI46_HUMAN             Reviewed;         759 AA.
AC   Q7Z4K8; A0AVI6; B1AVQ4; Q5VT60; Q5VT62; Q6NT17; Q6NT41; Q6ZRL7;
AC   Q9H5P2;
DE   RecName: Full=Tripartite motif-containing protein 46;
DE   AltName: Full=Gene Y protein;
DE            Short=GeneY;
DE   AltName: Full=Tripartite, fibronectin type-III and C-terminal SPRY motif protein;
GN   Name=TRIM46; Synonyms=TRIFIC;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI48_HUMAN             Reviewed;         208 AA.
AC   Q8IWZ4; Q9BUW4;
DE   RecName: Full=Tripartite motif-containing protein 48;
DE   AltName: Full=RING finger protein 101;
GN   Name=TRIM48; Synonyms=RNF101;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI49_HUMAN             Reviewed;         452 AA.
AC   P0CI25; A0AVR7; A0AVR9; Q6DJV1; Q9NS80;
DE   RecName: Full=Tripartite motif-containing protein 49;
DE   AltName: Full=RING finger protein 18;
DE   AltName: Full=Testis-specific RING-finger protein;
GN   Name=TRIM49; Synonyms=RNF18;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI50_HUMAN             Reviewed;         487 AA.
AC   Q86XT4; Q86XT3;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM50;
DE            EC=6.3.2.-;
DE   AltName: Full=Tripartite motif-containing protein 50;
GN   Name=TRIM50; Synonyms=TRIM50A;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI52_HUMAN             Reviewed;         297 AA.
AC   Q96A61;
DE   RecName: Full=Tripartite motif-containing protein 52;
DE   AltName: Full=RING finger protein 102;
GN   Name=TRIM52; Synonyms=RNF102;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
//
ID   TRI54_HUMAN             Reviewed;         358 AA.
AC   Q9BYV2; A5D8T7; Q53SY4; Q9BYV3;
DE   RecName: Full=Tripartite motif-containing protein 54;
DE   AltName: Full=Muscle-specific RING finger protein;
DE            Short=MuRF;
DE   AltName: Full=Muscle-specific RING finger protein 3;
DE            Short=MuRF-3;
DE            Short=MuRF3;
DE   AltName: Full=RING finger protein 30;
GN   Name=TRIM54; Synonyms=MURF, MURF3, RNF30;
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007017; P:microtubule-based process; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007026; P:negative regulation of microtubule depolymerization; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   TRI51_HUMAN             Reviewed;         452 AA.
AC   Q9BSJ1; A6NMG2;
DE   RecName: Full=Tripartite motif-containing protein 51;
DE   AltName: Full=SPRY domain-containing protein 5;
GN   Name=TRIM51; Synonyms=SPRYD5;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI55_HUMAN             Reviewed;         548 AA.
AC   Q9BYV6; B3KRC0; B3KRJ3; Q53XX3; Q8IUD9; Q8IUE4; Q96DV2; Q96DV3;
AC   Q9BYV5;
DE   RecName: Full=Tripartite motif-containing protein 55;
DE   AltName: Full=Muscle-specific RING finger protein 2;
DE            Short=MuRF-2;
DE            Short=MuRF2;
DE   AltName: Full=RING finger protein 29;
GN   Name=TRIM55; Synonyms=MURF2, RNF29;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
//
ID   TRI56_HUMAN             Reviewed;         755 AA.
AC   Q9BRZ2; Q6PJS5; Q86VT6; Q8N2H8; Q8NAC0; Q9H031;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM56;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 109;
DE   AltName: Full=Tripartite motif-containing protein 56;
GN   Name=TRIM56; Synonyms=RNF109;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051607; P:defense response to virus; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032608; P:interferon-beta production; ISS:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0034340; P:response to type I interferon; ISS:UniProtKB.
//
ID   TRI58_HUMAN             Reviewed;         486 AA.
AC   Q8NG06; Q6B0H9;
DE   RecName: Full=Tripartite motif-containing protein 58;
DE   AltName: Full=Protein BIA2;
GN   Name=TRIM58;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI59_HUMAN             Reviewed;         403 AA.
AC   Q8IWR1; A8K5G9; D3DNL9;
DE   RecName: Full=Tripartite motif-containing protein 59;
DE   AltName: Full=RING finger protein 104;
DE   AltName: Full=Tumor suppressor TSBF-1;
GN   Name=TRIM59; Synonyms=RNF104, TRIM57, TSBF1;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:MGI.
//
ID   TRI60_HUMAN             Reviewed;         471 AA.
AC   Q495X7; Q8NA35;
DE   RecName: Full=Tripartite motif-containing protein 60;
DE   AltName: Full=RING finger protein 129;
DE   AltName: Full=RING finger protein 33;
GN   Name=TRIM60; Synonyms=RNF129, RNF33;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI62_HUMAN             Reviewed;         475 AA.
AC   Q9BVG3; B3KVH5; D3DPR1; Q9NVG0;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM62;
DE            EC=6.3.2.-;
DE   AltName: Full=Tripartite motif-containing protein 62;
GN   Name=TRIM62;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IMP:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProt.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046596; P:regulation of viral entry into host cell; IDA:UniProt.
DR   GO; GO:1902186; P:regulation of viral release from host cell; IMP:UniProt.
//
ID   TRI61_HUMAN             Reviewed;         209 AA.
AC   Q5EBN2;
DE   RecName: Full=Putative tripartite motif-containing protein 61;
DE   AltName: Full=RING finger protein 35;
GN   Name=TRIM61; Synonyms=RNF35;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI63_HUMAN             Reviewed;         353 AA.
AC   Q969Q1; Q5T2I1; Q96BD3; Q96KD9; Q9BYV4;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM63;
DE            EC=6.3.2.-;
DE   AltName: Full=Iris RING finger protein;
DE   AltName: Full=Muscle-specific RING finger protein 1;
DE            Short=MuRF-1;
DE            Short=MuRF1;
DE   AltName: Full=RING finger protein 28;
DE   AltName: Full=Striated muscle RING zinc finger protein;
DE   AltName: Full=Tripartite motif-containing protein 63;
GN   Name=TRIM63; Synonyms=IRF, MURF1, RNF28, SMRZ;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; NAS:UniProtKB.
DR   GO; GO:0031432; F:titin binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; ISS:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0014732; P:skeletal muscle atrophy; IEA:Ensembl.
//
ID   TRI64_HUMAN             Reviewed;         449 AA.
AC   A6NGJ6;
DE   RecName: Full=Tripartite motif-containing protein 64;
GN   Name=TRIM64; Synonyms=C11orf28;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI65_HUMAN             Reviewed;         517 AA.
AC   Q6PJ69; Q4G0F0; Q6DKJ6; Q9BRP6;
DE   RecName: Full=Tripartite motif-containing protein 65;
GN   Name=TRIM65;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI67_HUMAN             Reviewed;         783 AA.
AC   Q6ZTA4; Q5TER7; Q5TER8; Q7Z4K7;
DE   RecName: Full=Tripartite motif-containing protein 67;
DE   AltName: Full=TRIM9-like protein;
GN   Name=TRIM67; Synonyms=TNL;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0046580; P:negative regulation of Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   TRI66_HUMAN             Reviewed;        1216 AA.
AC   O15016; Q9BQQ4;
DE   RecName: Full=Tripartite motif-containing protein 66;
GN   Name=TRIM66; Synonyms=C11orf29, KIAA0298;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI68_HUMAN             Reviewed;         485 AA.
AC   Q6AZZ1; A6NI19; A8K551; B3KPM5; Q8WZ70; Q96LE5; Q96PF7; Q9H9C2;
AC   Q9NW18;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM68;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 137;
DE   AltName: Full=SSA protein SS-56;
DE            Short=SS-56;
DE   AltName: Full=Tripartite motif-containing protein 68;
GN   Name=TRIM68; Synonyms=GC109, RNF137, SS56;
DR   GO; GO:0050681; F:androgen receptor binding; IPI:UniProtKB.
DR   GO; GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.
//
ID   TRI69_HUMAN             Reviewed;         500 AA.
AC   Q86WT6; A8MX03; Q309B0; Q4G1A5; Q6W897; Q8IYY3; Q8WY16; Q8WY17;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM69;
DE            EC=6.3.2.-;
DE   AltName: Full=RFP-like domain-containing protein trimless;
DE   AltName: Full=RING finger protein 36;
DE   AltName: Full=Tripartite motif-containing protein 69;
GN   Name=TRIM69; Synonyms=RNF36; ORFNames=HSD-34, HSD34;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   TRI72_HUMAN             Reviewed;         477 AA.
AC   Q6ZMU5; Q8N4X6; Q8NBD9;
DE   RecName: Full=Tripartite motif-containing protein 72;
DE   AltName: Full=Mitsugumin-53;
DE            Short=Mg53;
GN   Name=TRIM72; Synonyms=MG53;
DR   GO; GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; ISS:UniProtKB.
DR   GO; GO:0003012; P:muscle system process; ISS:UniProtKB.
DR   GO; GO:0001778; P:plasma membrane repair; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
//
ID   TRI73_HUMAN             Reviewed;         250 AA.
AC   Q86UV7; Q8N0S3;
DE   RecName: Full=Tripartite motif-containing protein 73;
DE   AltName: Full=Tripartite motif-containing protein 50B;
GN   Name=TRIM73; Synonyms=TRIM50B;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI74_HUMAN             Reviewed;         250 AA.
AC   Q86UV6; B7WP46;
DE   RecName: Full=Tripartite motif-containing protein 74;
DE   AltName: Full=Tripartite motif-containing protein 50C;
GN   Name=TRIM74; Synonyms=TRIM50C;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI77_HUMAN             Reviewed;         450 AA.
AC   I1YAP6;
DE   RecName: Full=Tripartite motif-containing protein 77;
GN   Name=TRIM77; Synonyms=TRIM77P;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRI75_HUMAN             Reviewed;         468 AA.
AC   A6NK02;
DE   RecName: Full=Putative tripartite motif-containing protein 75;
GN   Name=TRIM75;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRIA1_HUMAN             Reviewed;          76 AA.
AC   O43715; B2R4Z7; Q5RKS5; Q6LCA7;
DE   RecName: Full=TP53-regulated inhibitor of apoptosis 1;
DE   AltName: Full=Protein 15E1.1;
DE   AltName: Full=WF-1;
DE   AltName: Full=p53-inducible cell-survival factor;
DE            Short=p53CSV;
GN   Name=TRIAP1; Synonyms=15E1.1; ORFNames=HSPC132;
DR   GO; GO:0002039; F:p53 binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:BHF-UCL.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IDA:BHF-UCL.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:HGNC.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.
DR   GO; GO:0015914; P:phospholipid transport; IDA:GOC.
DR   GO; GO:2001140; P:positive regulation of phospholipid transport; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0097035; P:regulation of membrane lipid distribution; IMP:UniProtKB.
//
ID   TRIB1_HUMAN             Reviewed;         372 AA.
AC   Q96RU8; B4DMM6; C5HU08; O15180; Q9H2Y8;
DE   RecName: Full=Tribbles homolog 1;
DE            Short=TRB-1;
DE   AltName: Full=G-protein-coupled receptor-induced gene 2 protein;
DE            Short=GIG-2;
DE   AltName: Full=SKIP1;
GN   Name=TRIB1; Synonyms=C8FW, GIG2, TRB1;
DR   GO; GO:0031434; F:mitogen-activated protein kinase kinase binding; IDA:BHF-UCL.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IMP:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.
DR   GO; GO:0055106; F:ubiquitin-protein ligase regulator activity; ISS:BHF-UCL.
DR   GO; GO:0007254; P:JNK cascade; IMP:BHF-UCL.
DR   GO; GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0014912; P:negative regulation of smooth muscle cell migration; IMP:BHF-UCL.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0043405; P:regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IMP:BHF-UCL.
//
ID   TRIB2_HUMAN             Reviewed;         343 AA.
AC   Q92519; B2R851; D6W510;
DE   RecName: Full=Tribbles homolog 2;
DE            Short=TRB-2;
GN   Name=TRIB2; Synonyms=TRB2;
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0008134; F:transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.
DR   GO; GO:0055106; F:ubiquitin-protein ligase regulator activity; ISS:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045081; P:negative regulation of interleukin-10 biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; NAS:BHF-UCL.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.
//
ID   TRIB3_HUMAN             Reviewed;         358 AA.
AC   Q96RU7; Q53GU4; Q53ZW7; Q6I9Y9; Q8TAI6; Q9H5M8; Q9NUD2;
DE   RecName: Full=Tribbles homolog 3;
DE            Short=TRB-3;
DE   AltName: Full=Neuronal cell death-inducible putative kinase;
DE   AltName: Full=SINK;
DE   AltName: Full=p65-interacting inhibitor of NF-kappa-B;
GN   Name=TRIB3; Synonyms=C20orf97, NIPK, SKIP3, TRB3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.
DR   GO; GO:0055106; F:ubiquitin-protein ligase regulator activity; ISS:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:BHF-UCL.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0032092; P:positive regulation of protein binding; ISS:BHF-UCL.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR   GO; GO:0010827; P:regulation of glucose transport; ISS:BHF-UCL.
DR   GO; GO:0043405; P:regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TRIL_HUMAN              Reviewed;         811 AA.
AC   Q7L0X0; A4D1A6; O75139;
DE   RecName: Full=TLR4 interactor with leucine rich repeats;
DE   AltName: Full=Leucine-rich repeat-containing protein KIAA0644;
DE   Flags: Precursor;
GN   Name=TRIL; Synonyms=KIAA0644;
DR   GO; GO:0001530; F:lipopolysaccharide binding; IDA:UniProtKB.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0002718; P:regulation of cytokine production involved in immune response; IDA:UniProtKB.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; IDA:UniProtKB.
//
ID   TRIM1_HUMAN             Reviewed;         735 AA.
AC   Q9UJV3; A6NEL8; A6PVI5; Q5JYF5; Q8WWK1; Q9UJR9;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase MID2;
DE            EC=6.3.2.-;
DE   AltName: Full=Midin-2;
DE   AltName: Full=Midline defect 2;
DE   AltName: Full=Midline-2;
DE   AltName: Full=RING finger protein 60;
DE   AltName: Full=Tripartite motif-containing protein 1;
GN   Name=MID2; Synonyms=FXY2, RNF60, TRIM1;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IMP:UniProt.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProt.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0032897; P:negative regulation of viral transcription; IDA:UniProt.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProt.
DR   GO; GO:0035372; P:protein localization to microtubule; IMP:UniProt.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   TRIM2_HUMAN             Reviewed;         744 AA.
AC   Q9C040; D3DP09; O60272; Q9BSI9; Q9UFZ1;
DE   RecName: Full=Tripartite motif-containing protein 2;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ubiquitin-protein ligase TRIM2;
DE   AltName: Full=RING finger protein 86;
GN   Name=TRIM2; Synonyms=KIAA0517, RNF86;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; ISS:UniProtKB.
//
ID   TRIM3_HUMAN             Reviewed;         744 AA.
AC   O75382; B7Z5E6; F5H2Q8; Q4V9L4; Q9C038; Q9C039;
DE   RecName: Full=Tripartite motif-containing protein 3;
DE   AltName: Full=Brain-expressed RING finger protein;
DE   AltName: Full=RING finger protein 22;
DE   AltName: Full=RING finger protein 97;
GN   Name=TRIM3; Synonyms=BERP, RNF22, RNF97;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   TRIM4_HUMAN             Reviewed;         500 AA.
AC   Q9C037; A4D298; Q75MK1; Q96F06; Q9C036;
DE   RecName: Full=Tripartite motif-containing protein 4;
DE   AltName: Full=RING finger protein 87;
GN   Name=TRIM4; Synonyms=RNF87;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
//
ID   TRIM5_HUMAN             Reviewed;         493 AA.
AC   Q9C035; A6NGQ1; A8WFA8; D3DQS8; D3DQS9; G3GJY1; Q2MLV4; Q2MLV8;
AC   Q2MLV9; Q2MLW1; Q2MLW3; Q2MLW4; Q2MLW6; Q2MLW7; Q2MLX1; Q2MLX2;
AC   Q2MLX3; Q2MLX5; Q2MLY3; Q2MLY4; Q2V6Q6; Q6GX26; Q8WU46; Q96SR5;
AC   Q9C031; Q9C032; Q9C033; Q9C034;
DE   RecName: Full=Tripartite motif-containing protein 5;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 88;
GN   Name=TRIM5; Synonyms=RNF88;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008329; F:signaling pattern recognition receptor activity; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002218; P:activation of innate immune response; IDA:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; TAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:0046597; P:negative regulation of viral entry into host cell; IDA:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0002221; P:pattern recognition receptor signaling pathway; IDA:GOC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProt.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
DR   GO; GO:0031664; P:regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TRIM6_HUMAN             Reviewed;         488 AA.
AC   Q9C030; A8K2A7; B4DDQ5; Q86WZ8; Q9HCR1;
DE   RecName: Full=Tripartite motif-containing protein 6;
DE   AltName: Full=RING finger protein 89;
GN   Name=TRIM6; Synonyms=RNF89;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0070206; P:protein trimerization; IDA:UniProtKB.
//
ID   TRIM7_HUMAN             Reviewed;         511 AA.
AC   Q9C029; A2RUE4; D3DWR7; Q969F5; Q96F67; Q96J89; Q96J90;
DE   RecName: Full=Tripartite motif-containing protein 7;
DE   AltName: Full=Glycogenin-interacting protein;
DE   AltName: Full=RING finger protein 90;
GN   Name=TRIM7; Synonyms=GNIP, RNF90;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TRIM8_HUMAN             Reviewed;         551 AA.
AC   Q9BZR9; A6NI31; Q9C028;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase TRIM8;
DE            EC=6.3.2.-;
DE   AltName: Full=Glioblastoma-expressed RING finger protein;
DE   AltName: Full=RING finger protein 27;
DE   AltName: Full=Tripartite motif-containing protein 8;
GN   Name=TRIM8; Synonyms=GERP, RNF27;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IDA:UniProt.
DR   GO; GO:1902187; P:negative regulation of viral release from host cell; IDA:UniProt.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IDA:UniProt.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProt.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProt.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   TRIM9_HUMAN             Reviewed;         710 AA.
AC   Q9C026; D3DSB7; D3DSB8; Q92557; Q96D24; Q96NI4; Q9C025; Q9C027;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIM9;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 91;
DE   AltName: Full=Tripartite motif-containing protein 9;
GN   Name=TRIM9; Synonyms=KIAA0282, RNF91;
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0035544; P:negative regulation of SNARE complex assembly; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IEA:Ensembl.
//
ID   TRIML_HUMAN             Reviewed;         468 AA.
AC   Q8N9V2; Q96BE5;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase TRIML1;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 209;
DE   AltName: Full=Tripartite motif family-like protein 1;
GN   Name=TRIML1; Synonyms=RNF209;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   TRIMM_HUMAN             Reviewed;         387 AA.
AC   Q8N7C3;
DE   RecName: Full=Probable E3 ubiquitin-protein ligase TRIML2;
DE            EC=6.3.2.-;
DE   AltName: Full=SPRY domain-containing protein 6;
DE   AltName: Full=Tripartite motif family-like protein 2;
GN   Name=TRIML2; Synonyms=SPRYD6;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
//
ID   TRIO_HUMAN              Reviewed;        3097 AA.
AC   O75962; D3DTD1; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8;
DE   RecName: Full=Triple functional domain protein;
DE            EC=2.7.11.1;
DE   AltName: Full=PTPRF-interacting protein;
GN   Name=TRIO;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043087; P:regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:ProtInc.
//
ID   TRIP4_HUMAN             Reviewed;         581 AA.
AC   Q15650; B2RAS0; Q96ED7; Q9UKH0;
DE   RecName: Full=Activating signal cointegrator 1;
DE            Short=ASC-1;
DE   AltName: Full=Thyroid receptor-interacting protein 4;
DE            Short=TR-interacting protein 4;
DE            Short=TRIP-4;
GN   Name=TRIP4;
DR   GO; GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   TRIP6_HUMAN             Reviewed;         476 AA.
AC   Q15654; A4D2E7; F2ZC07; F2ZC08; O15170; O15275; Q9BTB2; Q9BUE5;
AC   Q9BXP3; Q9UNT4;
DE   RecName: Full=Thyroid receptor-interacting protein 6;
DE            Short=TR-interacting protein 6;
DE            Short=TRIP-6;
DE   AltName: Full=Opa-interacting protein 1;
DE            Short=OIP-1;
DE   AltName: Full=Zyxin-related protein 1;
DE            Short=ZRP-1;
GN   Name=TRIP6; Synonyms=OIP1;
DR   GO; GO:0005149; F:interleukin-1 receptor binding; IDA:UniProtKB.
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TRIPB_HUMAN             Reviewed;        1979 AA.
AC   Q15643; O14689; O15154; O95949;
DE   RecName: Full=Thyroid receptor-interacting protein 11;
DE            Short=TR-interacting protein 11;
DE            Short=TRIP-11;
DE   AltName: Full=Clonal evolution-related gene on chromosome 14 protein;
DE   AltName: Full=Golgi-associated microtubule-binding protein 210;
DE            Short=GMAP-210;
DE   AltName: Full=Trip230;
GN   Name=TRIP11; Synonyms=CEV14;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0000042; P:protein targeting to Golgi; IEA:InterPro.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   TRIPC_HUMAN             Reviewed;        1992 AA.
AC   Q14669; D4HL82; Q14CA3; Q14CF1; Q15644; Q53R87; Q53TE7;
DE   RecName: Full=E3 ubiquitin-protein ligase TRIP12;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ubiquitin-protein ligase for Arf;
DE            Short=ULF;
DE   AltName: Full=Thyroid receptor-interacting protein 12;
DE            Short=TR-interacting protein 12;
DE            Short=TRIP-12;
GN   Name=TRIP12; Synonyms=KIAA0045, ULF;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:2000780; P:negative regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:1901315; P:negative regulation of histone H2A K63-linked ubiquitination; IMP:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   TRIQK_HUMAN             Reviewed;          86 AA.
AC   Q629K1;
DE   RecName: Full=Triple QxxK/R motif-containing protein;
DE   AltName: Full=Triple repetitive-sequence of QXXK/R protein homolog;
GN   Name=TRIQK; Synonyms=C8orf83;
//
ID   TRM11_HUMAN             Reviewed;         463 AA.
AC   Q7Z4G4; E1P570; Q5JY11; Q6PGQ5; Q9HC13;
DE   RecName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog;
DE            EC=2.1.1.-;
DE   AltName: Full=tRNA guanosine-2'-O-methyltransferase TRM11 homolog;
GN   Name=TRMT11; Synonyms=C6orf75; ORFNames=MDS024;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TRM13_HUMAN             Reviewed;         481 AA.
AC   Q9NUP7; Q5VVL0; Q9NW65;
DE   RecName: Full=tRNA:m(4)X modification enzyme TRM13 homolog;
DE            EC=2.1.1.225;
DE   AltName: Full=Coiled-coil domain-containing protein 76;
GN   Name=TRMT13; Synonyms=CCDC76;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TRM1L_HUMAN             Reviewed;         733 AA.
AC   Q7Z2T5; Q5TEN0; Q6ZMX0; Q8IWH5; Q8NC68; Q9BZQ1;
DE   RecName: Full=TRMT1-like protein;
DE            EC=2.1.1.-;
GN   Name=TRMT1L; Synonyms=C1orf25, TRM1L; ORFNames=MSTP070;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004809; F:tRNA (guanine-N2-)-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
//
ID   TRM1_HUMAN              Reviewed;         659 AA.
AC   Q9NXH9; O76103; Q548Y5; Q8WVA6;
DE   RecName: Full=tRNA (guanine(26)-N(2))-dimethyltransferase;
DE            EC=2.1.1.216;
DE   AltName: Full=tRNA 2,2-dimethylguanosine-26 methyltransferase;
DE   AltName: Full=tRNA(guanine-26,N(2)-N(2)) methyltransferase;
DE   AltName: Full=tRNA(m(2,2)G26)dimethyltransferase;
GN   Name=TRMT1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004809; F:tRNA (guanine-N2-)-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
//
ID   TRM2A_HUMAN             Reviewed;         625 AA.
AC   Q8IZ69; D3DX25; Q32P57; Q96ME6; Q9H732;
DE   RecName: Full=tRNA (uracil-5-)-methyltransferase homolog A;
DE            EC=2.1.1.-;
DE   AltName: Full=HpaII tiny fragments locus 9c protein;
GN   Name=TRMT2A; Synonyms=HTF9C;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   TRM2_HUMAN              Reviewed;         504 AA.
AC   Q96GJ1; A6NDG5; A6NEI9; A6NMG6; Q5JPF0; Q5JVY6; Q96HU7; Q96IH9;
AC   Q9H9K2;
DE   RecName: Full=tRNA (uracil(54)-C(5))-methyltransferase homolog;
DE            EC=2.1.1.35;
DE   AltName: Full=TRM2 homolog;
GN   Name=TRMT2B; Synonyms=CXorf34;
DR   GO; GO:0030697; F:S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity; IEA:UniProtKB-EC.
//
ID   TRM44_HUMAN             Reviewed;         757 AA.
AC   Q8IYL2; Q8NA95;
DE   RecName: Full=Probable tRNA (uracil-O(2)-)-methyltransferase;
DE            EC=2.1.1.211;
DE   AltName: Full=Methyltransferase-like protein 19;
GN   Name=TRMT44; Synonyms=C4orf23, METTL19;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TRM5_HUMAN              Reviewed;         509 AA.
AC   Q32P41; B2RN19; Q9P2F4;
DE   RecName: Full=tRNA (guanine(37)-N1)-methyltransferase;
DE            EC=2.1.1.228;
DE   AltName: Full=M1G-methyltransferase;
DE   AltName: Full=tRNA [GM37] methyltransferase;
DE   AltName: Full=tRNA methyltransferase 5 homolog;
GN   Name=TRMT5; Synonyms=KIAA1393, TRM5;
DR   GO; GO:0052906; F:tRNA (guanine(37)-N(1))-methyltransferase activity; IEA:UniProtKB-EC.
//
ID   TRM61_HUMAN             Reviewed;         289 AA.
AC   Q96FX7; A6NN78; Q8N7Q9;
DE   RecName: Full=tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A;
DE            EC=2.1.1.220;
DE   AltName: Full=tRNA(m1A58)-methyltransferase subunit TRMT61A;
DE            Short=tRNA(m1A58)MTase subunit TRMT61A;
GN   Name=TRMT61A; Synonyms=C14orf172, TRM61;
DR   GO; GO:0016429; F:tRNA (adenine-N1-)-methyltransferase activity; IEA:InterPro.
//
ID   TRM6_HUMAN              Reviewed;         497 AA.
AC   Q9UJA5; B4DUV6; Q76P92; Q9BQV5; Q9ULR7; Q9Y2Z8;
DE   RecName: Full=tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6;
DE   AltName: Full=tRNA(m1A58)-methyltransferase subunit TRM6;
DE            Short=tRNA(m1A58)MTase subunit TRM6;
GN   Name=TRMT6; Synonyms=KIAA1153, TRM6; ORFNames=CGI-09;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TRM7_HUMAN              Reviewed;         329 AA.
AC   Q9UET6; B2RCJ0; O75670;
DE   RecName: Full=Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase;
DE            EC=2.1.1.205;
DE   AltName: Full=2'-O-ribose RNA methyltransferase TRM7 homolog;
DE   AltName: Full=Protein ftsJ homolog 1;
GN   Name=FTSJ1; ORFNames=JM23;
DR   GO; GO:0008175; F:tRNA methyltransferase activity; IEA:InterPro.
//
ID   TRMB_HUMAN              Reviewed;         276 AA.
AC   Q9UBP6; B2RBX1; H7BXF2; Q14105; Q53FS9;
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase;
DE            EC=2.1.1.33;
DE   AltName: Full=Methyltransferase-like protein 1;
DE   AltName: Full=tRNA (guanine(46)-N(7))-methyltransferase;
DE   AltName: Full=tRNA(m7G46)-methyltransferase;
GN   Name=METTL1; Synonyms=C12orf1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008176; F:tRNA (guanine-N7-)-methyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0036265; P:RNA (guanine-N7)-methylation; IDA:GOC.
DR   GO; GO:0006400; P:tRNA modification; IDA:UniProtKB.
//
ID   TRML1_HUMAN             Reviewed;         311 AA.
AC   Q86YW5; Q496B3; Q8IWY1; Q8IWY2;
DE   RecName: Full=Trem-like transcript 1 protein;
DE            Short=TLT-1;
DE   AltName: Full=Triggering receptor expressed on myeloid cells-like protein 1;
DE   Flags: Precursor;
GN   Name=TREML1; Synonyms=TLT1; ORFNames=UNQ1825/PRO3438;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
//
ID   TRML2_HUMAN             Reviewed;         321 AA.
AC   Q5T2D2; Q08AP8; Q08AP9; Q8IWY0; Q9H8E9;
DE   RecName: Full=Trem-like transcript 2 protein;
DE            Short=TLT-2;
DE   AltName: Full=Triggering receptor expressed on myeloid cells-like protein 2;
DE   Flags: Precursor;
GN   Name=TREML2; Synonyms=C6orf76, TLT2; ORFNames=UNQ6268/PRO20473;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; IDA:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; IDA:UniProtKB.
//
ID   TRML4_HUMAN             Reviewed;         200 AA.
AC   Q6UXN2; B7ZL92;
DE   RecName: Full=Trem-like transcript 4 protein;
DE            Short=TLT-4;
DE   AltName: Full=Triggering receptor expressed on myeloid cells-like protein 4;
DE   Flags: Precursor;
GN   Name=TREML4; Synonyms=TLT4; ORFNames=UNQ9425/PRO34675;
//
ID   TRNK1_HUMAN             Reviewed;        2925 AA.
AC   O15050; Q8N8K0;
DE   RecName: Full=TPR and ankyrin repeat-containing protein 1;
DE   AltName: Full=Lupus brain antigen 1 homolog;
GN   Name=TRANK1; Synonyms=KIAA0342, LBA1;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
//
ID   TRNT1_HUMAN             Reviewed;         434 AA.
AC   Q96Q11; A8K2Z6; B7WP13; C9JKA2; Q8ND57; Q9BS97; Q9Y362;
DE   RecName: Full=CCA tRNA nucleotidyltransferase 1, mitochondrial;
DE            EC=2.7.7.72;
DE   AltName: Full=Mitochondrial tRNA nucleotidyl transferase, CCA-adding;
DE   AltName: Full=mt CCA-adding enzyme;
DE   AltName: Full=mt tRNA CCA-diphosphorylase;
DE   AltName: Full=mt tRNA CCA-pyrophosphorylase;
DE   AltName: Full=mt tRNA adenylyltransferase;
DE   Flags: Precursor;
GN   Name=TRNT1; ORFNames=CGI-47;
DR   GO; GO:0005524; F:ATP binding; TAS:UniProtKB.
DR   GO; GO:0052929; F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052928; F:CTP:3'-cytidine-tRNA cytidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052927; F:CTP:tRNA cytidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004810; F:tRNA adenylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:UniProtKB.
DR   GO; GO:0042780; P:tRNA 3'-end processing; IDA:UniProtKB.
DR   GO; GO:0001680; P:tRNA 3'-terminal CCA addition; IEA:UniProtKB-EC.
//
ID   TRNP1_HUMAN             Reviewed;         227 AA.
AC   Q6NT89;
DE   RecName: Full=TMF-regulated nuclear protein 1;
GN   Name=TRNP1; Synonyms=C1orf225, TRNP;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0021696; P:cerebellar cortex morphogenesis; ISS:UniProtKB.
DR   GO; GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TROAP_HUMAN             Reviewed;         778 AA.
AC   Q12815; Q6PJU7; Q8N5B2;
DE   RecName: Full=Tastin;
DE   AltName: Full=Trophinin-assisting protein;
DE   AltName: Full=Trophinin-associated protein;
GN   Name=TROAP;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
//
ID   TROP_HUMAN              Reviewed;        1431 AA.
AC   Q12816; B1AKE9; B1AKF1; F5GY27; Q96SX2; Q9NU89; Q9UPN8;
DE   RecName: Full=Trophinin;
DE   AltName: Full=MAGE-D3 antigen;
GN   Name=TRO; Synonyms=KIAA1114, MAGED3;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007566; P:embryo implantation; TAS:ProtInc.
DR   GO; GO:0007156; P:homophilic cell adhesion; TAS:ProtInc.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
//
ID   TRPA1_HUMAN             Reviewed;        1119 AA.
AC   O75762; A6NIN6;
DE   RecName: Full=Transient receptor potential cation channel subfamily A member 1;
DE   AltName: Full=Ankyrin-like with transmembrane domains protein 1;
DE   AltName: Full=Transformation-sensitive protein p120;
GN   Name=TRPA1; Synonyms=ANKTM1;
DR   GuidetoPHARMACOLOGY; 485; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0015267; F:channel activity; TAS:ProtInc.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050968; P:detection of chemical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:ProtInc.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
DR   GO; GO:0050955; P:thermoception; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPC1_HUMAN             Reviewed;         793 AA.
AC   P48995; Q14CE4;
DE   RecName: Full=Short transient receptor potential channel 1;
DE            Short=TrpC1;
DE   AltName: Full=Transient receptor protein 1;
DE            Short=TRP-1;
GN   Name=TRPC1; Synonyms=TRP1;
DR   GuidetoPHARMACOLOGY; 486; -.
DR   GO; GO:0005262; F:calcium channel activity; TAS:ProtInc.
DR   GO; GO:0005261; F:cation channel activity; EXP:Reactome.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0051480; P:cytosolic calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0046541; P:saliva secretion; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPC3_HUMAN             Reviewed;         836 AA.
AC   Q13507; A7VJS1; E9PCJ9; O00593; Q15660; Q52M35; Q5G1L5;
DE   RecName: Full=Short transient receptor potential channel 3;
DE            Short=TrpC3;
DE   AltName: Full=Transient receptor protein 3;
DE            Short=TRP-3;
DE            Short=hTrp-3;
DE            Short=hTrp3;
GN   Name=TRPC3; Synonyms=TRP3;
DR   GuidetoPHARMACOLOGY; 488; -.
DR   GO; GO:0005262; F:calcium channel activity; TAS:ProtInc.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007602; P:phototransduction; TAS:ProtInc.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0010524; P:positive regulation of calcium ion transport into cytosol; IDA:UniProtKB.
DR   GO; GO:0033198; P:response to ATP; IDA:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPC4_HUMAN             Reviewed;         977 AA.
AC   Q9UBN4; B1ALE0; B1ALE1; B1ALE2; Q15721; Q3SWS6; Q96P03; Q96P04;
AC   Q96P05; Q9UIB0; Q9UIB1; Q9UIB2;
DE   RecName: Full=Short transient receptor potential channel 4;
DE            Short=TrpC4;
DE   AltName: Full=Trp-related protein 4;
DE            Short=hTrp-4;
DE            Short=hTrp4;
GN   Name=TRPC4;
DR   GuidetoPHARMACOLOGY; 489; -.
DR   GO; GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; IPI:BHF-UCL.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IMP:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070509; P:calcium ion import; IDA:BHF-UCL.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0014051; P:gamma-aminobutyric acid secretion; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPC5_HUMAN             Reviewed;         973 AA.
AC   Q9UL62; B2RP53; O75233; Q5JXY8; Q9Y514;
DE   RecName: Full=Short transient receptor potential channel 5;
DE            Short=TrpC5;
DE   AltName: Full=Transient receptor protein 5;
DE            Short=TRP-5;
DE            Short=hTRP-5;
DE            Short=hTRP5;
GN   Name=TRPC5; Synonyms=TRP5;
DR   GuidetoPHARMACOLOGY; 490; -.
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPC6_HUMAN             Reviewed;         931 AA.
AC   Q9Y210; Q52M59; Q9HCW3; Q9NQA8; Q9NQA9;
DE   RecName: Full=Short transient receptor potential channel 6;
DE            Short=TrpC6;
DE   AltName: Full=Transient receptor protein 6;
DE            Short=TRP-6;
GN   Name=TRPC6; Synonyms=TRP6;
DR   GuidetoPHARMACOLOGY; 491; -.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006812; P:cation transport; TAS:ProtInc.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:MGI.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0032414; P:positive regulation of ion transmembrane transporter activity; IDA:MGI.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPC7_HUMAN             Reviewed;         862 AA.
AC   Q9HCX4; A1A4Z4; F5H5U9; Q70T26; Q8IWP7;
DE   RecName: Full=Short transient receptor potential channel 7;
DE            Short=TrpC7;
DE   AltName: Full=Transient receptor protein 7;
DE            Short=TRP-7;
DE            Short=hTRP7;
GN   Name=TRPC7; Synonyms=TRP7;
DR   GuidetoPHARMACOLOGY; 492; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006828; P:manganese ion transport; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM1_HUMAN             Reviewed;        1603 AA.
AC   Q7Z4N2; D9IDV2; D9IDV3; F8W865; H0YN37; O75560; Q6PE48; Q7Z4N1;
AC   Q7Z4N3; Q7Z4N4; Q7Z4N5;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 1;
DE   AltName: Full=Long transient receptor potential channel 1;
DE            Short=LTrpC1;
DE   AltName: Full=Melastatin-1;
GN   Name=TRPM1; Synonyms=LTRPC1, MLSN, MLSN1;
DR   GuidetoPHARMACOLOGY; 493; -.
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; IDA:UniProtKB.
DR   GO; GO:0071482; P:cellular response to light stimulus; IMP:UniProtKB.
DR   GO; GO:0007216; P:G-protein coupled glutamate receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0046548; P:retinal rod cell development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; IMP:UniProtKB.
//
ID   TRPM2_HUMAN             Reviewed;        1503 AA.
AC   O94759; D3DSL6; Q5KTC2; Q6J3P5; Q96KN6; Q96Q93;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 2;
DE            EC=3.6.1.13;
DE   AltName: Full=Estrogen-responsive element-associated gene 1 protein;
DE   AltName: Full=Long transient receptor potential channel 2;
DE            Short=LTrpC-2;
DE            Short=LTrpC2;
DE   AltName: Full=Transient receptor potential channel 7;
DE            Short=TrpC7;
GN   Name=TRPM2; Synonyms=EREG1, KNP3, LTRPC2, TRPC7;
DR   GuidetoPHARMACOLOGY; 494; -.
DR   GO; GO:0047631; F:ADP-ribose diphosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005262; F:calcium channel activity; TAS:ProtInc.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0033194; P:response to hydroperoxide; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM3_HUMAN             Reviewed;        1732 AA.
AC   Q9HCF6; A2A3F6; A9Z1Y7; Q5VW02; Q5VW03; Q5VW04; Q5W5T7; Q86SH0;
AC   Q86SH6; Q86UL0; Q86WK1; Q86WK2; Q86WK3; Q86WK4; Q86YZ9; Q86Z00;
AC   Q86Z01; Q9H0X2;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 3;
DE   AltName: Full=Long transient receptor potential channel 3;
DE            Short=LTrpC-3;
DE            Short=LTrpC3;
DE   AltName: Full=Melastatin-2;
DE            Short=MLSN2;
GN   Name=TRPM3; Synonyms=KIAA1616, LTRPC3;
DR   GuidetoPHARMACOLOGY; 495; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005261; F:cation channel activity; IDA:MGI.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006812; P:cation transport; IDA:MGI.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM4_HUMAN             Reviewed;        1214 AA.
AC   Q8TD43; A2RU25; Q7Z5D9; Q96L84; Q9NXV1;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 4;
DE            Short=hTRPM4;
DE   AltName: Full=Calcium-activated non-selective cation channel 1;
DE   AltName: Full=Long transient receptor potential channel 4;
DE            Short=LTrpC-4;
DE            Short=LTrpC4;
DE   AltName: Full=Melastatin-4;
GN   Name=TRPM4; Synonyms=LTRPC4;
DR   GuidetoPHARMACOLOGY; 496; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005227; F:calcium activated cation channel activity; ISS:UniProtKB.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0002407; P:dendritic cell chemotaxis; ISS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0016925; P:protein sumoylation; IDA:UniProtKB.
DR   GO; GO:0002724; P:regulation of T cell cytokine production; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM5_HUMAN             Reviewed;        1165 AA.
AC   Q9NZQ8; A6NHS0; Q52LU2; Q9NY34;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 5;
DE   AltName: Full=Long transient receptor potential channel 5;
DE            Short=LTrpC-5;
DE            Short=LTrpC5;
DE   AltName: Full=MLSN1- and TRP-related gene 1 protein;
GN   Name=TRPM5; Synonyms=LTRPC5, MTR1;
DR   GuidetoPHARMACOLOGY; 497; -.
DR   GO; GO:0005227; F:calcium activated cation channel activity; IEA:Ensembl.
DR   GO; GO:0005216; F:ion channel activity; TAS:ProtInc.
DR   GO; GO:0005267; F:potassium channel activity; IEA:Ensembl.
DR   GO; GO:0005272; F:sodium channel activity; IEA:Ensembl.
DR   GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM6_HUMAN             Reviewed;        2022 AA.
AC   Q9BX84; Q6VPR8; Q6VPR9; Q6VPS0; Q6VPS1; Q6VPS2;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 6;
DE            EC=2.7.11.1;
DE   AltName: Full=Channel kinase 2;
DE   AltName: Full=Melastatin-related TRP cation channel 6;
GN   Name=TRPM6; Synonyms=CHAK2;
DR   GuidetoPHARMACOLOGY; 498; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM7_HUMAN             Reviewed;        1865 AA.
AC   Q96QT4; Q6ZMF5; Q86VJ4; Q8NBW2; Q9BXB2; Q9NXQ2;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 7;
DE            EC=2.7.11.1;
DE   AltName: Full=Channel-kinase 1;
DE   AltName: Full=Long transient receptor potential channel 7;
DE            Short=LTrpC-7;
DE            Short=LTrpC7;
GN   Name=TRPM7; Synonyms=CHAK1, LTRPC7;
DR   GuidetoPHARMACOLOGY; 499; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031032; P:actomyosin structure organization; IEA:Ensembl.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0016340; P:calcium-dependent cell-matrix adhesion; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0070266; P:necroptotic process; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPM8_HUMAN             Reviewed;        1104 AA.
AC   Q7Z2W7; A0AVG2; Q3YFM7; Q6QNH9; Q8TAC3; Q8TDX8; Q9BVK1;
DE   RecName: Full=Transient receptor potential cation channel subfamily M member 8;
DE   AltName: Full=Long transient receptor potential channel 6;
DE            Short=LTrpC-6;
DE            Short=LTrpC6;
DE   AltName: Full=Transient receptor potential p8;
DE            Short=Trp-p8;
GN   Name=TRPM8; Synonyms=LTRPC6, TRPP8;
DR   GuidetoPHARMACOLOGY; 500; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:Ensembl.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:Ensembl.
DR   GO; GO:0070207; P:protein homotrimerization; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0050955; P:thermoception; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPS1_HUMAN             Reviewed;        1281 AA.
AC   Q9UHF7; B4E1Z5; Q08AU2; Q9NWE1; Q9UHH6;
DE   RecName: Full=Zinc finger transcription factor Trps1;
DE   AltName: Full=Tricho-rhino-phalangeal syndrome type I protein;
DE   AltName: Full=Zinc finger protein GC79;
GN   Name=TRPS1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006607; P:NLS-bearing protein import into nucleus; TAS:ProtInc.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0032330; P:regulation of chondrocyte differentiation; ISS:UniProtKB.
DR   GO; GO:0031063; P:regulation of histone deacetylation; IEA:InterPro.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0007178; P:transmembrane receptor protein serine/threonine kinase signaling pathway; IEA:Ensembl.
//
ID   TRPT1_HUMAN             Reviewed;         253 AA.
AC   Q86TN4; A8MU17; A8MYC9; F5H2B2; Q9BSB9;
DE   RecName: Full=tRNA 2'-phosphotransferase 1;
DE            EC=2.7.1.160;
GN   Name=TRPT1;
DR   GO; GO:0000215; F:tRNA 2'-phosphotransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0006388; P:tRNA splicing, via endonucleolytic cleavage and ligation; IEA:Ensembl.
//
ID   TRPV1_HUMAN             Reviewed;         839 AA.
AC   Q8NER1; A2RUA9; Q9H0G9; Q9H303; Q9H304; Q9NQ74; Q9NY22;
DE   RecName: Full=Transient receptor potential cation channel subfamily V member 1;
DE            Short=TrpV1;
DE   AltName: Full=Capsaicin receptor;
DE   AltName: Full=Osm-9-like TRP channel 1;
DE            Short=OTRPC1;
DE   AltName: Full=Vanilloid receptor 1;
GN   Name=TRPV1; Synonyms=VR1;
DR   GuidetoPHARMACOLOGY; 507; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0005262; F:calcium channel activity; TAS:ProtInc.
DR   GO; GO:0015278; F:calcium-release channel activity; ISS:UniProtKB.
DR   GO; GO:0005231; F:excitatory extracellular ligand-gated ion channel activity; ISS:UniProtKB.
DR   GO; GO:0051219; F:phosphoprotein binding; IPI:UniProt.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; ISS:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0071312; P:cellular response to alkaloid; ISS:UniProtKB.
DR   GO; GO:0071318; P:cellular response to ATP; ISS:UniProtKB.
DR   GO; GO:0007635; P:chemosensory behavior; TAS:ProtInc.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0050955; P:thermoception; IDA:MGI.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   TRPV2_HUMAN             Reviewed;         764 AA.
AC   Q9Y5S1; A6NML2; A8K0Z0; Q9Y670;
DE   RecName: Full=Transient receptor potential cation channel subfamily V member 2;
DE            Short=TrpV2;
DE   AltName: Full=Osm-9-like TRP channel 2;
DE            Short=OTRPC2;
DE   AltName: Full=Vanilloid receptor-like protein 1;
DE            Short=VRL-1;
GN   Name=TRPV2; Synonyms=VRL;
DR   GuidetoPHARMACOLOGY; 508; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005261; F:cation channel activity; IDA:MGI.
DR   GO; GO:0005216; F:ion channel activity; TAS:ProtInc.
DR   GO; GO:0015075; F:ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045773; P:positive regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0009266; P:response to temperature stimulus; IDA:MGI.
DR   GO; GO:0007600; P:sensory perception; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   TRPV3_HUMAN             Reviewed;         790 AA.
AC   Q8NET8; Q8NDW7; Q8NET9; Q8NFH2;
DE   RecName: Full=Transient receptor potential cation channel subfamily V member 3;
DE            Short=TrpV3;
DE   AltName: Full=Vanilloid receptor-like 3;
DE            Short=VRL-3;
GN   Name=TRPV3;
DR   GuidetoPHARMACOLOGY; 509; -.
DR   GO; GO:0005262; F:calcium channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0042636; P:negative regulation of hair cycle; IMP:UniProtKB.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0009408; P:response to heat; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPV4_HUMAN             Reviewed;         871 AA.
AC   Q9HBA0; B7ZKQ6; Q17R79; Q2Y122; Q2Y123; Q2Y124; Q86YZ6; Q8NDY7;
AC   Q8NG64; Q96Q92; Q96RS7; Q9HBC0;
DE   RecName: Full=Transient receptor potential cation channel subfamily V member 4;
DE            Short=TrpV4;
DE   AltName: Full=Osm-9-like TRP channel 4;
DE            Short=OTRPC4;
DE   AltName: Full=Transient receptor potential protein 12;
DE            Short=TRP12;
DE   AltName: Full=Vanilloid receptor-like channel 2;
DE   AltName: Full=Vanilloid receptor-like protein 2;
DE            Short=VRL-2;
DE   AltName: Full=Vanilloid receptor-related osmotically-activated channel;
DE            Short=VR-OAC;
GN   Name=TRPV4; Synonyms=VRL2, VROAC;
DR   GuidetoPHARMACOLOGY; 510; -.
DR   GO; GO:0003779; F:actin binding; ISS:BHF-UCL.
DR   GO; GO:0051015; F:actin filament binding; ISS:BHF-UCL.
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048487; F:beta-tubulin binding; ISS:BHF-UCL.
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IMP:UniProtKB.
DR   GO; GO:0005261; F:cation channel activity; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; ISS:BHF-UCL.
DR   GO; GO:0005034; F:osmosensor activity; IEA:Ensembl.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; ISS:BHF-UCL.
DR   GO; GO:0042169; F:SH2 domain binding; ISS:BHF-UCL.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; ISS:BHF-UCL.
DR   GO; GO:0007015; P:actin filament organization; ISS:BHF-UCL.
DR   GO; GO:0070509; P:calcium ion import; ISS:BHF-UCL.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006884; P:cell volume homeostasis; TAS:UniProtKB.
DR   GO; GO:0007043; P:cell-cell junction assembly; ISS:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0071476; P:cellular hypotonic response; ISS:BHF-UCL.
DR   GO; GO:0034605; P:cellular response to heat; ISS:UniProtKB.
DR   GO; GO:0071470; P:cellular response to osmotic stress; ISS:UniProtKB.
DR   GO; GO:0043622; P:cortical microtubule organization; ISS:BHF-UCL.
DR   GO; GO:0042538; P:hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0046785; P:microtubule polymerization; ISS:BHF-UCL.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:BHF-UCL.
DR   GO; GO:0007231; P:osmosensory signaling pathway; TAS:UniProtKB.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IDA:UniProtKB.
DR   GO; GO:0031117; P:positive regulation of microtubule depolymerization; ISS:BHF-UCL.
DR   GO; GO:0047484; P:regulation of response to osmotic stress; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; TAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0030103; P:vasopressin secretion; IEA:Ensembl.
//
ID   TRPV5_HUMAN             Reviewed;         729 AA.
AC   Q9NQA5; A4D2H7; Q8NDW5; Q8NDX7; Q8NDX8; Q96PM6;
DE   RecName: Full=Transient receptor potential cation channel subfamily V member 5;
DE            Short=TrpV5;
DE   AltName: Full=Calcium transport protein 2;
DE            Short=CaT2;
DE   AltName: Full=Epithelial calcium channel 1;
DE            Short=ECaC;
DE            Short=ECaC1;
DE   AltName: Full=Osm-9-like TRP channel 3;
DE            Short=OTRPC3;
GN   Name=TRPV5; Synonyms=ECAC1;
DR   GuidetoPHARMACOLOGY; 511; -.
DR   GO; GO:0005262; F:calcium channel activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; ISS:UniProtKB.
DR   GO; GO:0060402; P:calcium ion transport into cytosol; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0051262; P:protein tetramerization; ISS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRPV6_HUMAN             Reviewed;         725 AA.
AC   Q9H1D0; A4D2I8; Q8TDL3; Q8WXR8; Q96LC5; Q9H1D1; Q9H296;
DE   RecName: Full=Transient receptor potential cation channel subfamily V member 6;
DE            Short=TrpV6;
DE   AltName: Full=CaT-like;
DE            Short=CaT-L;
DE   AltName: Full=Calcium transport protein 1;
DE            Short=CaT1;
DE   AltName: Full=Epithelial calcium channel 2;
DE            Short=ECaC2;
GN   Name=TRPV6; Synonyms=ECAC2;
DR   GuidetoPHARMACOLOGY; 512; -.
DR   GO; GO:0005262; F:calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0005516; F:calmodulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0006816; P:calcium ion transport; NAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0017158; P:regulation of calcium ion-dependent exocytosis; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TRRAP_HUMAN             Reviewed;        3859 AA.
AC   Q9Y4A5; A4D265; O75218; Q9Y631; Q9Y6H4;
DE   RecName: Full=Transformation/transcription domain-associated protein;
DE   AltName: Full=350/400 kDa PCAF-associated factor;
DE            Short=PAF350/400;
DE   AltName: Full=STAF40;
DE   AltName: Full=Tra1 homolog;
GN   Name=TRRAP; Synonyms=PAF400;
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0016573; P:histone acetylation; NAS:UniProtKB.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TRUA_HUMAN              Reviewed;         427 AA.
AC   Q9Y606; A8K877; B3KQC1; Q8WYT2; Q9BU44;
DE   RecName: Full=tRNA pseudouridine synthase A, mitochondrial;
DE            EC=5.4.99.12;
DE   AltName: Full=tRNA pseudouridine(38-40) synthase;
DE   AltName: Full=tRNA pseudouridylate synthase I;
DE   AltName: Full=tRNA-uridine isomerase I;
DE   Flags: Precursor;
GN   Name=PUS1; ORFNames=PP8985;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004730; F:pseudouridylate synthase activity; NAS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031119; P:tRNA pseudouridine synthesis; IEA:Ensembl.
//
ID   TRUB1_HUMAN             Reviewed;         349 AA.
AC   Q8WWH5; B2R716; Q53ES2;
DE   RecName: Full=Probable tRNA pseudouridine synthase 1;
DE            EC=5.4.99.-;
GN   Name=TRUB1; Synonyms=PUS4;
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TRUB2_HUMAN             Reviewed;         331 AA.
AC   O95900;
DE   RecName: Full=Probable tRNA pseudouridine synthase 2;
DE            EC=5.4.99.-;
GN   Name=TRUB2;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TRXR1_HUMAN             Reviewed;         649 AA.
AC   Q16881; B7Z1F4; B7Z3Y8; B7Z904; E9PMY9; F5H780; Q6FI31; Q6VB40;
AC   Q6VB41; Q6VB42; Q6VBP2; Q6VBP3; Q6VBP4; Q6VBP5; Q6VBP9; Q6VBQ0;
AC   Q6YNQ1; Q76P53; Q7LA96; Q8WVC8; Q99475; Q9UES8; Q9UH79;
DE   RecName: Full=Thioredoxin reductase 1, cytoplasmic;
DE            Short=TR;
DE            EC=1.8.1.9;
DE   AltName: Full=Gene associated with retinoic and interferon-induced mortality 12 protein;
DE            Short=GRIM-12;
DE            Short=Gene associated with retinoic and IFN-induced mortality 12 protein;
DE   AltName: Full=KM-102-derived reductase-like factor;
DE   AltName: Full=Thioredoxin reductase TR1;
GN   Name=TXNRD1; Synonyms=GRIM12, KDRF;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase activity; EXP:Reactome.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TRXR2_HUMAN             Reviewed;         524 AA.
AC   Q9NNW7; O95840; Q96IJ2; Q9H2Z5; Q9NZV3; Q9NZV4; Q9P2Y0; Q9P2Y1;
AC   Q9UQU8;
DE   RecName: Full=Thioredoxin reductase 2, mitochondrial;
DE            EC=1.8.1.9;
DE   AltName: Full=Selenoprotein Z;
DE            Short=SelZ;
DE   AltName: Full=TR-beta;
DE   AltName: Full=Thioredoxin reductase TR3;
DE   Flags: Precursor;
GN   Name=TXNRD2; Synonyms=KIAA1652, TRXR2;
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase activity; ISS:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0000305; P:response to oxygen radical; TAS:UniProtKB.
//
ID   TRXR3_HUMAN             Reviewed;         643 AA.
AC   Q86VQ6; Q6PIS8; Q9NNW6; Q9P101;
DE   RecName: Full=Thioredoxin reductase 3;
DE            EC=1.8.1.9;
DE   AltName: Full=Thioredoxin and glutathione reductase;
DE   AltName: Full=Thioredoxin reductase TR2;
GN   Name=TXNRD3; Synonyms=TGR, TRXR3;
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TRY1_HUMAN              Reviewed;         247 AA.
AC   P07477; A1A509; A6NJ71; B2R5I5; Q5NV57; Q7M4N3; Q7M4N4; Q92955;
AC   Q9HAN4; Q9HAN5; Q9HAN6; Q9HAN7;
DE   RecName: Full=Trypsin-1;
DE            EC=3.4.21.4;
DE   AltName: Full=Beta-trypsin;
DE   AltName: Full=Cationic trypsinogen;
DE   AltName: Full=Serine protease 1;
DE   AltName: Full=Trypsin I;
DE   Contains:
DE     RecName: Full=Alpha-trypsin chain 1;
DE   Contains:
DE     RecName: Full=Alpha-trypsin chain 2;
DE   Flags: Precursor;
GN   Name=PRSS1; Synonyms=TRP1, TRY1, TRYP1;
DR   GuidetoPHARMACOLOGY; 2397; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
//
ID   TRY2_HUMAN              Reviewed;         247 AA.
AC   P07478;
DE   RecName: Full=Trypsin-2;
DE            EC=3.4.21.4;
DE   AltName: Full=Anionic trypsinogen;
DE   AltName: Full=Serine protease 2;
DE   AltName: Full=Trypsin II;
DE   Flags: Precursor;
GN   Name=PRSS2; Synonyms=TRY2, TRYP2;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0030574; P:collagen catabolic process; IDA:UniProtKB.
DR   GO; GO:0007586; P:digestion; IEA:UniProtKB-KW.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; TAS:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   TRY3_HUMAN              Reviewed;         304 AA.
AC   P35030; A8CED1; A8CED3; A9Z1Y4; E7ES07; F8W7P3; P15951; Q15665;
AC   Q5VXV0; Q6ISJ4; Q9UQV3;
DE   RecName: Full=Trypsin-3;
DE            EC=3.4.21.4;
DE   AltName: Full=Brain trypsinogen;
DE   AltName: Full=Mesotrypsinogen;
DE   AltName: Full=Serine protease 3;
DE   AltName: Full=Serine protease 4;
DE   AltName: Full=Trypsin III;
DE   AltName: Full=Trypsin IV;
DE   Flags: Precursor;
GN   Name=PRSS3; Synonyms=PRSS4, TRY3, TRY4;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; IDA:UniProtKB.
DR   GO; GO:0009235; P:cobalamin metabolic process; TAS:Reactome.
DR   GO; GO:0007586; P:digestion; TAS:UniProtKB.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; IDA:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006766; P:vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0006767; P:water-soluble vitamin metabolic process; TAS:Reactome.
DR   GO; GO:0031638; P:zymogen activation; IDA:UniProtKB.
//
ID   TRY6_HUMAN              Reviewed;         247 AA.
AC   Q8NHM4;
DE   RecName: Full=Putative trypsin-6;
DE            EC=3.4.21.4;
DE   AltName: Full=Serine protease 3 pseudogene 2;
DE   AltName: Full=Trypsinogen C;
DE   Flags: Precursor;
GN   Name=PRSS3P2; Synonyms=T6, TRY6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0043542; P:endothelial cell migration; IMP:UniProtKB.
//
ID   TRYB1_HUMAN             Reviewed;         275 AA.
AC   Q15661; D2E6R9; D2E6S1; P15157; Q15663; Q6B052; Q9H2Y4; Q9H2Y5;
AC   Q9UQI1;
DE   RecName: Full=Tryptase alpha/beta-1;
DE            Short=Tryptase-1;
DE            EC=3.4.21.59;
DE   AltName: Full=Tryptase I;
DE   AltName: Full=Tryptase alpha-1;
DE   Flags: Precursor;
GN   Name=TPSAB1; Synonyms=TPS1, TPS2, TPSB1;
DR   GuidetoPHARMACOLOGY; 2424; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0022617; P:extracellular matrix disassembly; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
//
ID   TRYB2_HUMAN             Reviewed;         275 AA.
AC   P20231; D2E6S0; D2E6S2; O95827; Q15664; Q9UQI6; Q9UQI7;
DE   RecName: Full=Tryptase beta-2;
DE            Short=Tryptase-2;
DE            EC=3.4.21.59;
DE   AltName: Full=Tryptase II;
DE   Flags: Precursor;
GN   Name=TPSB2; Synonyms=TPS2;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; NAS:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   TRYD_HUMAN              Reviewed;         242 AA.
AC   Q9BZJ3; O95824; Q8TDI6; Q96L36; Q96RZ5; Q9H2Y6; Q9UQI8;
DE   RecName: Full=Tryptase delta;
DE            EC=3.4.21.59;
DE   AltName: Full=Delta-tryptase;
DE   AltName: Full=HmMCP-3-like tryptase III;
DE   AltName: Full=Mast cell mMCP-7-like;
DE   AltName: Full=Tryptase-3;
DE   Flags: Precursor;
GN   Name=TPSD1;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   TRYG1_HUMAN             Reviewed;         321 AA.
AC   Q9NRR2; Q96RZ8; Q9C015; Q9NRQ8; Q9UBB2;
DE   RecName: Full=Tryptase gamma;
DE            EC=3.4.21.-;
DE   AltName: Full=Serine protease 31;
DE   AltName: Full=Transmembrane tryptase;
DE   Contains:
DE     RecName: Full=Tryptase gamma light chain;
DE   Contains:
DE     RecName: Full=Tryptase gamma heavy chain;
DE   Flags: Precursor;
GN   Name=TPSG1; Synonyms=PRSS31, TMT;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0008236; F:serine-type peptidase activity; TAS:ProtInc.
//
ID   TS101_HUMAN             Reviewed;         390 AA.
AC   Q99816; Q9BUM5;
DE   RecName: Full=Tumor susceptibility gene 101 protein;
DE   AltName: Full=ESCRT-I complex subunit TSG101;
GN   Name=TSG101;
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProt.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0046755; P:viral budding; ISS:UniProtKB.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   TS1R1_HUMAN             Reviewed;         841 AA.
AC   Q7RTX1; B2RMX0; Q5SY22; Q5SY24; Q8NGZ7; Q8TDJ7; Q8TDJ8; Q8TDJ9;
AC   Q8TDK0;
DE   RecName: Full=Taste receptor type 1 member 1;
DE   AltName: Full=G-protein coupled receptor 70;
DE   Flags: Precursor;
GN   Name=TAS1R1; Synonyms=GPR70, T1R1, TR1; ORFNames=GM148;
DR   GO; GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.
DR   GO; GO:0008527; F:taste receptor activity; IDA:UniProtKB.
DR   GO; GO:0050912; P:detection of chemical stimulus involved in sensory perception of taste; IDA:GOC.
DR   GO; GO:0050917; P:sensory perception of umami taste; IDA:UniProtKB.
//
ID   TS1R2_HUMAN             Reviewed;         839 AA.
AC   Q8TE23; Q5TZ19;
DE   RecName: Full=Taste receptor type 1 member 2;
DE   AltName: Full=G-protein coupled receptor 71;
DE   AltName: Full=Sweet taste receptor T1R2;
DE   Flags: Precursor;
GN   Name=TAS1R2; Synonyms=GPR71, T1R2, TR2;
DR   GO; GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.
DR   GO; GO:0008527; F:taste receptor activity; IDA:UniProtKB.
DR   GO; GO:0001582; P:detection of chemical stimulus involved in sensory perception of sweet taste; IDA:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IC:HGNC.
DR   GO; GO:0032467; P:positive regulation of cytokinesis; IMP:UniProt.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IDA:UniProtKB.
//
ID   TS1R3_HUMAN             Reviewed;         852 AA.
AC   Q7RTX0; Q5TA49; Q8NGW9;
DE   RecName: Full=Taste receptor type 1 member 3;
DE   AltName: Full=Sweet taste receptor T1R3;
DE   Flags: Precursor;
GN   Name=TAS1R3; Synonyms=T1R3, TR3;
DR   GO; GO:0046982; F:protein heterodimerization activity; NAS:UniProtKB.
DR   GO; GO:0008527; F:taste receptor activity; IDA:UniProtKB.
DR   GO; GO:0001582; P:detection of chemical stimulus involved in sensory perception of sweet taste; IDA:HGNC.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; IC:HGNC.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IDA:UniProtKB.
DR   GO; GO:0050917; P:sensory perception of umami taste; IDA:UniProtKB.
//
ID   TSACC_HUMAN             Reviewed;         125 AA.
AC   Q96A04; D3DVB9;
DE   RecName: Full=TSSK6-activating co-chaperone protein;
DE   AltName: Full=SSTK-interacting protein;
DE            Short=SSTK-IP;
GN   Name=TSACC; Synonyms=C1orf182;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
//
ID   TSAP1_HUMAN             Reviewed;         287 AA.
AC   Q9NX07; Q86SU7;
DE   RecName: Full=tRNA selenocysteine 1-associated protein 1;
DE   AltName: Full=SECp43;
DE   AltName: Full=tRNA selenocysteine-associated protein 1;
GN   Name=TRNAU1AP; Synonyms=SECP43, TRSPAP1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0001514; P:selenocysteine incorporation; ISS:HGNC.
//
ID   TSC1_HUMAN              Reviewed;        1164 AA.
AC   Q92574; B7Z897; Q5VVN5;
DE   RecName: Full=Hamartin;
DE   AltName: Full=Tuberous sclerosis 1 protein;
GN   Name=TSC1; Synonyms=KIAA0243, TSC;
DR   GO; GO:0051087; F:chaperone binding; IPI:UniProtKB.
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.
DR   GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0030030; P:cell projection organization; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0042552; P:myelination; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045792; P:negative regulation of cell size; IEA:Ensembl.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IMP:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0006813; P:potassium ion transport; IEA:Ensembl.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0001952; P:regulation of cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:0043666; P:regulation of phosphoprotein phosphatase activity; IMP:UniProtKB.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0051492; P:regulation of stress fiber assembly; IDA:UniProtKB.
DR   GO; GO:0006417; P:regulation of translation; IDA:UniProtKB.
DR   GO; GO:0032868; P:response to insulin; IDA:UniProtKB.
DR   GO; GO:0006407; P:rRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
//
ID   TSC2_HUMAN              Reviewed;        1807 AA.
AC   P49815; A7E2E2; B4DIL8; B4DIQ7; B4DRN2; C9J378; O75275; Q4LE71;
AC   Q8TAZ1;
DE   RecName: Full=Tuberin;
DE   AltName: Full=Tuberous sclerosis 2 protein;
GN   Name=TSC2; Synonyms=TSC4;
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006953; P:acute-phase response; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; TAS:Reactome.
DR   GO; GO:0030030; P:cell projection organization; IEA:Ensembl.
DR   GO; GO:0006897; P:endocytosis; TAS:ProtInc.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045792; P:negative regulation of cell size; IBA:RefGenome.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; ISS:UniProtKB.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; ISS:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IBA:RefGenome.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; ISS:UniProtKB.
DR   GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0008104; P:protein localization; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IBA:RefGenome.
DR   GO; GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.
DR   GO; GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   TSCOT_HUMAN             Reviewed;         475 AA.
AC   Q9BY10; B1ALK1; Q86VT0; Q96NE2;
DE   RecName: Full=Thymic stromal cotransporter homolog;
DE   AltName: Full=Solute carrier family 46 member 2;
GN   Name=SLC46A2; Synonyms=TSCOT;
DR   GO; GO:0015293; F:symporter activity; NAS:UniProtKB.
DR   GO; GO:0070233; P:negative regulation of T cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0045580; P:regulation of T cell differentiation; IEA:Ensembl.
DR   GO; GO:0043029; P:T cell homeostasis; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
//
ID   TSEAR_HUMAN             Reviewed;         669 AA.
AC   Q8WU66;
DE   RecName: Full=Thrombospondin-type laminin G domain and EAR repeat-containing protein;
DE            Short=TSP-EAR;
DE   Flags: Precursor;
GN   Name=TSPEAR; Synonyms=C21orf29;
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
//
ID   TSG10_HUMAN             Reviewed;         698 AA.
AC   Q9BZW7; B7Z925; D3DVH7; Q8NEP0; Q9BWX0;
DE   RecName: Full=Testis-specific gene 10 protein;
DE   AltName: Full=Testis development protein NYD-SP7;
GN   Name=TSGA10; Synonyms=CEP4L;
DR   GO; GO:0030031; P:cell projection assembly; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:UniProtKB.
//
ID   TSG13_HUMAN             Reviewed;         275 AA.
AC   Q96PP4; B3KSC9;
DE   RecName: Full=Testis-specific gene 13 protein;
GN   Name=TSGA13;
//
ID   TSG6_HUMAN              Reviewed;         277 AA.
AC   P98066; Q53TI7; Q8WWI9;
DE   RecName: Full=Tumor necrosis factor-inducible gene 6 protein;
DE   AltName: Full=Hyaluronate-binding protein;
DE   AltName: Full=TNF-stimulated gene 6 protein;
DE            Short=TSG-6;
DE   AltName: Full=Tumor necrosis factor alpha-induced protein 6;
DE            Short=TNF alpha-induced protein 6;
DE   Flags: Precursor;
GN   Name=TNFAIP6; Synonyms=TSG6;
DR   GO; GO:0005540; F:hyaluronic acid binding; TAS:ProtInc.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TSH1_HUMAN              Reviewed;        1077 AA.
AC   Q6ZSZ6; O60534; Q4LE29; Q53EU4;
DE   RecName: Full=Teashirt homolog 1;
DE   AltName: Full=Antigen NY-CO-33;
DE   AltName: Full=Serologically defined colon cancer antigen 33;
GN   Name=TSHZ1; Synonyms=SDCCAG33, TSH1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0042474; P:middle ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060023; P:soft palate development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TSH2_HUMAN              Reviewed;        1034 AA.
AC   Q9NRE2; B7Z7W1; J3KNQ0; Q4VXM4; Q6N003; Q8N260;
DE   RecName: Full=Teashirt homolog 2;
DE   AltName: Full=Ovarian cancer-related protein 10-2;
DE            Short=OVC10-2;
DE   AltName: Full=Zinc finger protein 218;
GN   Name=TSHZ2; Synonyms=C20orf17, TSH2, ZNF218;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TSH3_HUMAN              Reviewed;        1081 AA.
AC   Q63HK5; Q9H0G6; Q9P254;
DE   RecName: Full=Teashirt homolog 3;
DE   AltName: Full=Zinc finger protein 537;
GN   Name=TSHZ3; Synonyms=KIAA1474, TSH3, ZNF537;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060993; P:kidney morphogenesis; IEA:Ensembl.
DR   GO; GO:0072195; P:kidney smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0001656; P:metanephros development; IEA:Ensembl.
DR   GO; GO:0050881; P:musculoskeletal movement; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0051152; P:positive regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; ISS:UniProtKB.
DR   GO; GO:0050975; P:sensory perception of touch; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0072193; P:ureter smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0001657; P:ureteric bud development; IEA:Ensembl.
DR   GO; GO:0072105; P:ureteric peristalsis; IEA:Ensembl.
//
ID   TSHB_HUMAN              Reviewed;         138 AA.
AC   P01222; B1AKP0; Q16163;
DE   RecName: Full=Thyrotropin subunit beta;
DE   AltName: Full=Thyroid-stimulating hormone subunit beta;
DE            Short=TSH-B;
DE            Short=TSH-beta;
DE   AltName: Full=Thyrotropin beta chain;
DE   AltName: INN=Thyrotropin alfa;
DE   Flags: Precursor;
GN   Name=TSHB;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0016486; P:peptide hormone processing; TAS:Reactome.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0043627; P:response to estrogen; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
//
ID   TSHR_HUMAN              Reviewed;         764 AA.
AC   P16473; A0PJU7; F5GYU5; G3V2A9; Q16503; Q8TB90; Q96GT6; Q9P1V4;
AC   Q9ULA3; Q9UPH3;
DE   RecName: Full=Thyrotropin receptor;
DE   AltName: Full=Thyroid-stimulating hormone receptor;
DE            Short=TSH-R;
DE   Flags: Precursor;
GN   Name=TSHR; Synonyms=LGR3;
DR   GuidetoPHARMACOLOGY; 255; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004996; F:thyroid-stimulating hormone receptor activity; IEA:Ensembl.
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0040012; P:regulation of locomotion; IEA:Ensembl.
DR   GO; GO:0038194; P:thyroid-stimulating hormone signaling pathway; TAS:GOC.
//
ID   TSKS_HUMAN              Reviewed;         592 AA.
AC   Q9UJT2; Q8WXJ0;
DE   RecName: Full=Testis-specific serine kinase substrate;
DE            Short=Testis-specific kinase substrate;
DE   AltName: Full=STK22 substrate 1;
GN   Name=TSKS; Synonyms=STK22S1, TSKS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   TSK_HUMAN               Reviewed;         353 AA.
AC   Q8WUA8; B3KQT7; Q6UXK1; Q9UG10; Q9UJX9;
DE   RecName: Full=Tsukushin;
DE            Short=Tsukushi;
DE   AltName: Full=E2-induced gene 4 protein;
DE   AltName: Full=Leucine-rich repeat-containing protein 54;
DE   Flags: Precursor;
GN   Name=TSKU; Synonyms=E2IG4, LRRC54, TSK; ORFNames=UNQ850/PRO1788;
DR   GO; GO:0021960; P:anterior commissure morphogenesis; IEA:Ensembl.
DR   GO; GO:0061073; P:ciliary body morphogenesis; IEA:Ensembl.
DR   GO; GO:0021540; P:corpus callosum morphogenesis; IEA:Ensembl.
DR   GO; GO:0021670; P:lateral ventricle development; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
//
ID   TSLP_HUMAN              Reviewed;         159 AA.
AC   Q969D9; Q8IW99;
DE   RecName: Full=Thymic stromal lymphopoietin;
DE   Flags: Precursor;
GN   Name=TSLP;
//
ID   TSN10_HUMAN             Reviewed;         355 AA.
AC   Q9H1Z9; Q8N548;
DE   RecName: Full=Tetraspanin-10;
DE            Short=Tspan-10;
DE   AltName: Full=Oculospanin;
GN   Name=TSPAN10; Synonyms=OCSP;
//
ID   TSN11_HUMAN             Reviewed;         253 AA.
AC   A1L157; A1L158; B2RUX6;
DE   RecName: Full=Tetraspanin-11;
DE            Short=Tspan-11;
GN   Name=TSPAN11;
//
ID   TSN12_HUMAN             Reviewed;         305 AA.
AC   O95859; A4D0V8; B4DRG6; Q549U9; Q8N5Y0;
DE   RecName: Full=Tetraspanin-12;
DE            Short=Tspan-12;
DE   AltName: Full=Tetraspan NET-2;
DE   AltName: Full=Transmembrane 4 superfamily member 12;
GN   Name=TSPAN12; Synonyms=NET2, TM4SF12; ORFNames=UNQ774/PRO1568;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045765; P:regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0010842; P:retina layer formation; ISS:UniProtKB.
//
ID   TSN13_HUMAN             Reviewed;         204 AA.
AC   O95857;
DE   RecName: Full=Tetraspanin-13;
DE            Short=Tspan-13;
DE   AltName: Full=Tetraspan NET-6;
DE   AltName: Full=Transmembrane 4 superfamily member 13;
GN   Name=TSPAN13; Synonyms=NET6, TM4SF13; ORFNames=UNQ260/PRO296;
//
ID   TSN14_HUMAN             Reviewed;         270 AA.
AC   Q8NG11; A6NHE1; B4DHY6; D3DWD7; D3DWD8; Q567U7; Q9BU34; Q9H0U1;
DE   RecName: Full=Tetraspanin-14;
DE            Short=Tspan-14;
DE   AltName: Full=DC-TM4F2;
DE   AltName: Full=Transmembrane 4 superfamily member 14;
GN   Name=TSPAN14; Synonyms=TM4SF14;
//
ID   TSN15_HUMAN             Reviewed;         294 AA.
AC   O95858; Q6UW79;
DE   RecName: Full=Tetraspanin-15;
DE            Short=Tspan-15;
DE   AltName: Full=Tetraspan NET-7;
DE   AltName: Full=Transmembrane 4 superfamily member 15;
GN   Name=TSPAN15; Synonyms=NET7, TM4SF15; ORFNames=UNQ677/PRO1311;
//
ID   TSN17_HUMAN             Reviewed;         270 AA.
AC   Q96FV3; Q6NXF7; Q96S98; Q9UKB9;
DE   RecName: Full=Tetraspanin-17;
DE            Short=Tspan-17;
DE   AltName: Full=F-box only protein 23;
DE   AltName: Full=Tetraspan protein SB134;
DE   AltName: Full=Transmembrane 4 superfamily member 17;
GN   Name=TSPAN17; Synonyms=FBXO23, TM4SF17;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; NAS:UniProtKB.
//
ID   TSN16_HUMAN             Reviewed;         245 AA.
AC   Q9UKR8;
DE   RecName: Full=Tetraspanin-16;
DE            Short=Tspan-16;
DE   AltName: Full=Tetraspanin TM4-B;
DE   AltName: Full=Transmembrane 4 superfamily member 16;
GN   Name=TSPAN16; Synonyms=TM4SF16;
//
ID   TSN18_HUMAN             Reviewed;         248 AA.
AC   Q96SJ8; Q6UY44; Q8NBI9;
DE   RecName: Full=Tetraspanin-18;
DE            Short=Tspan-18;
GN   Name=TSPAN18; ORFNames=UNQ3042/PRO9858;
//
ID   TSN19_HUMAN             Reviewed;         248 AA.
AC   P0C672;
DE   RecName: Full=Putative tetraspanin-19;
DE            Short=Tspan-19;
GN   Name=TSPAN19;
//
ID   TSN1_HUMAN              Reviewed;         241 AA.
AC   O60635; D3DQ14; O60745; Q5VST0;
DE   RecName: Full=Tetraspanin-1;
DE            Short=Tspan-1;
DE   AltName: Full=Tetraspan NET-1;
DE   AltName: Full=Tetraspanin TM4-C;
GN   Name=TSPAN1;
//
ID   TSN2_HUMAN              Reviewed;         221 AA.
AC   O60636; D6PTH4; Q5TET2; Q8WU05;
DE   RecName: Full=Tetraspanin-2;
DE            Short=Tspan-2;
DE   AltName: Full=Tetraspan NET-3;
GN   Name=TSPAN2;
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
//
ID   TSN31_HUMAN             Reviewed;         210 AA.
AC   Q12999; O00577; Q53X76;
DE   RecName: Full=Tetraspanin-31;
DE            Short=Tspan-31;
DE   AltName: Full=Sarcoma-amplified sequence;
GN   Name=TSPAN31; Synonyms=SAS;
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
//
ID   TSN32_HUMAN             Reviewed;         320 AA.
AC   Q96QS1; Q96KX4; Q9HC50; Q9HC51; Q9Y5U1;
DE   RecName: Full=Tetraspanin-32;
DE            Short=Tspan-32;
DE   AltName: Full=Protein Phemx;
GN   Name=TSPAN32; Synonyms=PHEMX, TSSC6;
DR   GO; GO:0007267; P:cell-cell signaling; TAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0042832; P:defense response to protozoan; IEA:Ensembl.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030886; P:negative regulation of myeloid dendritic cell activation; IEA:Ensembl.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0050688; P:regulation of defense response to virus; IEA:Ensembl.
//
ID   TSN33_HUMAN             Reviewed;         283 AA.
AC   Q86UF1;
DE   RecName: Full=Tetraspanin-33;
DE            Short=Tspan-33;
DE   AltName: Full=Penumbra;
DE            Short=hPen;
DE   AltName: Full=Proerythroblast new membrane;
GN   Name=TSPAN33; Synonyms=PEN;
//
ID   TSN3_HUMAN              Reviewed;         253 AA.
AC   O60637; A6NEH4; B3KQQ2; B4DP19; Q9BW22; Q9NVX9;
DE   RecName: Full=Tetraspanin-3;
DE            Short=Tspan-3;
DE   AltName: Full=Tetraspanin TM4-A;
DE   AltName: Full=Transmembrane 4 superfamily member 8;
GN   Name=TSPAN3; Synonyms=TM4SF8;
//
ID   TSN4_HUMAN              Reviewed;         238 AA.
AC   O14817; Q6IAP6;
DE   RecName: Full=Tetraspanin-4;
DE            Short=Tspan-4;
DE   AltName: Full=Novel antigen 2;
DE            Short=NAG-2;
DE   AltName: Full=Transmembrane 4 superfamily member 7;
GN   Name=TSPAN4; Synonyms=NAG2, TM4SF7;
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
//
ID   TSN5_HUMAN              Reviewed;         268 AA.
AC   P62079; B2RDY2; O60628; O60746; Q6FHE5; Q9JLY1;
DE   RecName: Full=Tetraspanin-5;
DE            Short=Tspan-5;
DE   AltName: Full=Tetraspan NET-4;
DE   AltName: Full=Transmembrane 4 superfamily member 9;
GN   Name=TSPAN5; Synonyms=TM4SF9;
//
ID   TSN6_HUMAN              Reviewed;         245 AA.
AC   O43657; Q54A42; Q6IAN9;
DE   RecName: Full=Tetraspanin-6;
DE            Short=Tspan-6;
DE   AltName: Full=A15 homolog;
DE   AltName: Full=Putative NF-kappa-B-activating protein 321;
DE   AltName: Full=T245 protein;
DE   AltName: Full=Tetraspanin TM4-D;
DE   AltName: Full=Transmembrane 4 superfamily member 6;
GN   Name=TSPAN6; Synonyms=TM4SF6; ORFNames=UNQ767/PRO1560;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   TSN8_HUMAN              Reviewed;         237 AA.
AC   P19075; B2R7T7; Q9BS78;
DE   RecName: Full=Tetraspanin-8;
DE            Short=Tspan-8;
DE   AltName: Full=Transmembrane 4 superfamily member 3;
DE   AltName: Full=Tumor-associated antigen CO-029;
GN   Name=TSPAN8; Synonyms=TM4SF3;
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IEA:Ensembl.
DR   GO; GO:0006486; P:protein glycosylation; TAS:ProtInc.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
//
ID   TSN7_HUMAN              Reviewed;         249 AA.
AC   P41732; B2R5W7; D3DWB1; Q8WVG5; Q9UEY9;
DE   RecName: Full=Tetraspanin-7;
DE            Short=Tspan-7;
DE   AltName: Full=Cell surface glycoprotein A15;
DE   AltName: Full=Membrane component chromosome X surface marker 1;
DE   AltName: Full=T-cell acute lymphoblastic leukemia-associated antigen 1;
DE            Short=TALLA-1;
DE   AltName: Full=Transmembrane 4 superfamily member 2;
DE   AltName: CD_antigen=CD231;
GN   Name=TSPAN7; Synonyms=A15, DXS1692E, MXS1, TM4SF2;
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   TSN9_HUMAN              Reviewed;         239 AA.
AC   O75954; D3DUQ7; Q53FV2; Q6FGJ8;
DE   RecName: Full=Tetraspanin-9;
DE            Short=Tspan-9;
DE   AltName: Full=Tetraspan NET-5;
GN   Name=TSPAN9; Synonyms=NET5;
//
ID   TSNAX_HUMAN             Reviewed;         290 AA.
AC   Q99598; B1APC6;
DE   RecName: Full=Translin-associated protein X;
DE   AltName: Full=Translin-associated factor X;
GN   Name=TSNAX; Synonyms=TRAX;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; TAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSNA1_HUMAN             Reviewed;         513 AA.
AC   Q96NA8; Q14D03;
DE   RecName: Full=t-SNARE domain-containing protein 1;
GN   Name=TSNARE1;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0016079; P:synaptic vesicle exocytosis; IBA:RefGenome.
//
ID   TSN_HUMAN               Reviewed;         228 AA.
AC   Q15631; B7Z3X8; Q5U0K7;
DE   RecName: Full=Translin;
DE            EC=3.1.-.-;
DE   AltName: Full=Component 3 of promoter of RISC;
DE            Short=C3PO;
GN   Name=TSN;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
//
ID   TSP1_HUMAN              Reviewed;        1170 AA.
AC   P07996; A8K6H4; B9EGH6; Q15667;
DE   RecName: Full=Thrombospondin-1;
DE   Flags: Precursor;
GN   Name=THBS1; Synonyms=TSP, TSP1;
DR   GO; GO:0005509; F:calcium ion binding; NAS:BHF-UCL.
DR   GO; GO:0070052; F:collagen V binding; IDA:BHF-UCL.
DR   GO; GO:0070051; F:fibrinogen binding; IDA:BHF-UCL.
DR   GO; GO:0017134; F:fibroblast growth factor binding; IDA:BHF-UCL.
DR   GO; GO:0001968; F:fibronectin binding; IDA:BHF-UCL.
DR   GO; GO:0001948; F:glycoprotein binding; NAS:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; NAS:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IMP:BHF-UCL.
DR   GO; GO:0043236; F:laminin binding; IDA:BHF-UCL.
DR   GO; GO:0030169; F:low-density lipoprotein particle binding; IDA:BHF-UCL.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043394; F:proteoglycan binding; TAS:BHF-UCL.
DR   GO; GO:0050431; F:transforming growth factor beta binding; ISS:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IMP:BHF-UCL.
DR   GO; GO:0048266; P:behavioral response to pain; ISS:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; NAS:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.
DR   GO; GO:0016477; P:cell migration; IDA:BHF-UCL.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0034605; P:cellular response to heat; NAS:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0002544; P:chronic inflammatory response; IEP:BHF-UCL.
DR   GO; GO:0003197; P:endocardial cushion development; IEA:Ensembl.
DR   GO; GO:0043652; P:engulfment of apoptotic cell; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IEP:BHF-UCL.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0002581; P:negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IDA:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001953; P:negative regulation of cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0010754; P:negative regulation of cGMP-mediated signaling; IDA:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0002605; P:negative regulation of dendritic cell antigen processing and presentation; IDA:BHF-UCL.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IDA:BHF-UCL.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051895; P:negative regulation of focal adhesion assembly; TAS:BHF-UCL.
DR   GO; GO:0032695; P:negative regulation of interleukin-12 production; IDA:BHF-UCL.
DR   GO; GO:0010751; P:negative regulation of nitric oxide mediated signal transduction; IDA:BHF-UCL.
DR   GO; GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IDA:BHF-UCL.
DR   GO; GO:0010757; P:negative regulation of plasminogen activation; IDA:BHF-UCL.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0018149; P:peptide cross-linking; IDA:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:BHF-UCL.
DR   GO; GO:0030194; P:positive regulation of blood coagulation; IDA:BHF-UCL.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0050921; P:positive regulation of chemotaxis; IDA:BHF-UCL.
DR   GO; GO:2000353; P:positive regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IDA:BHF-UCL.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; IDA:BHF-UCL.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IDA:BHF-UCL.
DR   GO; GO:0010759; P:positive regulation of macrophage chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0042327; P:positive regulation of phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:BHF-UCL.
DR   GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0032914; P:positive regulation of transforming growth factor beta1 production; ISS:BHF-UCL.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:BHF-UCL.
DR   GO; GO:0042535; P:positive regulation of tumor necrosis factor biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0051592; P:response to calcium ion; IDA:BHF-UCL.
DR   GO; GO:0042493; P:response to drug; IEP:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0009749; P:response to glucose; IDA:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; NAS:BHF-UCL.
DR   GO; GO:0032026; P:response to magnesium ion; IDA:BHF-UCL.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; TAS:BHF-UCL.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0002040; P:sprouting angiogenesis; IMP:BHF-UCL.
//
ID   TSP2_HUMAN              Reviewed;        1172 AA.
AC   P35442; A6H8N1; A7E232; Q5RI52;
DE   RecName: Full=Thrombospondin-2;
DE   Flags: Precursor;
GN   Name=THBS2; Synonyms=TSP2;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008201; F:heparin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
//
ID   TSP3_HUMAN              Reviewed;         956 AA.
AC   P49746; B1AVR8; B4DQ20; Q8WV34;
DE   RecName: Full=Thrombospondin-3;
DE   Flags: Precursor;
GN   Name=THBS3; Synonyms=TSP3;
DR   GO; GO:0005509; F:calcium ion binding; NAS:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:MGI.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.
DR   GO; GO:0003417; P:growth plate cartilage development; IEA:Ensembl.
DR   GO; GO:0043931; P:ossification involved in bone maturation; IEA:Ensembl.
//
ID   TSP4_HUMAN              Reviewed;         961 AA.
AC   P35443; B2R909; Q86TG2;
DE   RecName: Full=Thrombospondin-4;
DE   Flags: Precursor;
GN   Name=THBS4; Synonyms=TSP4;
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048266; P:behavioral response to pain; ISS:UniProtKB.
DR   GO; GO:0071603; P:endothelial cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0051451; P:myoblast migration; IDA:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IEP:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0034103; P:regulation of tissue remodeling; ISS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
DR   GO; GO:0048771; P:tissue remodeling; IEA:UniProtKB-KW.
//
ID   TSP50_HUMAN             Reviewed;         385 AA.
AC   Q9UI38;
DE   RecName: Full=Probable threonine protease PRSS50;
DE            EC=3.4.25.-;
DE   AltName: Full=Cancer/testis antigen 20;
DE   AltName: Full=Serine protease 50;
DE   AltName: Full=Testis-specific protease-like protein 50;
DE   Flags: Precursor;
GN   Name=PRSS50; Synonyms=CT20, TSP50;
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0004298; F:threonine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   TSPOB_HUMAN             Reviewed;         102 AA.
AC   B1AH88; Q13849; Q6IAZ7;
DE   RecName: Full=Putative peripheral benzodiazepine receptor-related protein;
GN   Name=TSPO; Synonyms=PBRS;
//
ID   TSPO2_HUMAN             Reviewed;         170 AA.
AC   Q5TGU0; B2RPR2; B7ZMN8; Q3SX82;
DE   RecName: Full=Translocator protein 2;
DE   AltName: Full=Peripheral-type benzodiazepine receptor-like protein 1;
GN   Name=TSPO2; Synonyms=BZRPL1;
DR   GO; GO:0015485; F:cholesterol binding; ISS:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   TSPOA_HUMAN             Reviewed;         169 AA.
AC   P30536; Q53Y59; Q6ICF9; Q96TF6;
DE   RecName: Full=Translocator protein;
DE   AltName: Full=Mitochondrial benzodiazepine receptor;
DE   AltName: Full=PKBS;
DE   AltName: Full=Peripheral-type benzodiazepine receptor;
DE            Short=PBR;
GN   Name=TSPO; Synonyms=BZRP, MBR;
DR   GO; GO:0005497; F:androgen binding; IEA:Ensembl.
DR   GO; GO:0008503; F:benzodiazepine receptor activity; TAS:ProtInc.
DR   GO; GO:0015485; F:cholesterol binding; TAS:HGNC.
DR   GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006820; P:anion transport; TAS:HGNC.
DR   GO; GO:0006915; P:apoptotic process; TAS:HGNC.
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:HGNC.
DR   GO; GO:0071476; P:cellular hypotonic response; IEA:Ensembl.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071294; P:cellular response to zinc ion; IEA:Ensembl.
DR   GO; GO:0006821; P:chloride transport; IEA:Ensembl.
DR   GO; GO:0060242; P:contact inhibition; IEA:Ensembl.
DR   GO; GO:0008347; P:glial cell migration; IEA:Ensembl.
DR   GO; GO:0006783; P:heme biosynthetic process; TAS:HGNC.
DR   GO; GO:0060253; P:negative regulation of glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0014012; P:peripheral nervous system axon regeneration; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0060252; P:positive regulation of glial cell proliferation; IEA:Ensembl.
DR   GO; GO:0051901; P:positive regulation of mitochondrial depolarization; IEA:Ensembl.
DR   GO; GO:0010940; P:positive regulation of necrotic cell death; IEA:Ensembl.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IEA:Ensembl.
DR   GO; GO:0006626; P:protein targeting to mitochondrion; TAS:ProtInc.
DR   GO; GO:0032374; P:regulation of cholesterol transport; TAS:HGNC.
DR   GO; GO:0050810; P:regulation of steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0010266; P:response to vitamin B1; IEA:Ensembl.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:HGNC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:GOC.
//
ID   TSPY1_HUMAN             Reviewed;         308 AA.
AC   Q01534; A6NJD2; O00216; P09002; Q0VAD3; Q9UNN7;
DE   RecName: Full=Testis-specific Y-encoded protein 1;
DE   AltName: Full=Cancer/testis antigen 78;
DE            Short=CT78;
GN   Name=TSPY1; Synonyms=TSPY;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007548; P:sex differentiation; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   TSPY3_HUMAN             Reviewed;         308 AA.
AC   P0CV98;
DE   RecName: Full=Testis-specific Y-encoded protein 3;
GN   Name=TSPY3;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSPY2_HUMAN             Reviewed;         308 AA.
AC   A6NKD2;
DE   RecName: Full=Testis-specific Y-encoded protein 2;
DE   AltName: Full=Testis-specific Y-encoded protein Q1;
GN   Name=TSPY2; Synonyms=TSPYQ1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSPY8_HUMAN             Reviewed;         308 AA.
AC   P0CW00; H7BXJ3;
DE   RecName: Full=Testis-specific Y-encoded protein 8;
GN   Name=TSPY8;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSPY4_HUMAN             Reviewed;         314 AA.
AC   P0CV99;
DE   RecName: Full=Testis-specific Y-encoded protein 4;
GN   Name=TSPY4;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSPYA_HUMAN             Reviewed;         314 AA.
AC   P0CW01;
DE   RecName: Full=Testis-specific Y-encoded protein 10;
GN   Name=TSPY10;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSR1_HUMAN              Reviewed;         804 AA.
AC   Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6;
DE   RecName: Full=Pre-rRNA-processing protein TSR1 homolog;
GN   Name=TSR1; Synonyms=KIAA1401;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0042255; P:ribosome assembly; ISS:UniProtKB.
//
ID   TSR2_HUMAN              Reviewed;         191 AA.
AC   Q969E8;
DE   RecName: Full=Pre-rRNA-processing protein TSR2 homolog;
GN   Name=TSR2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   TSR3_HUMAN              Reviewed;         312 AA.
AC   Q9UJK0; Q6PJT8;
DE   RecName: Full=Ribosome biogenesis protein TSR3 homolog;
GN   Name=TSR3; Synonyms=C16orf42, UND313L;
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-HAMAP.
//
ID   TSSC1_HUMAN             Reviewed;         387 AA.
AC   Q53HC9; D6W4Y1; O43179; Q53S19; Q53SG2;
DE   RecName: Full=Protein TSSC1;
DE   AltName: Full=Tumor-suppressing STF cDNA 1 protein;
DE   AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein;
GN   Name=TSSC1;
//
ID   TSSC4_HUMAN             Reviewed;         329 AA.
AC   Q9Y5U2; C9JS66; Q86VL2; Q9BRS6;
DE   RecName: Full=Protein TSSC4;
DE   AltName: Full=Tumor-suppressing STF cDNA 4 protein;
DE   AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein;
GN   Name=TSSC4;
//
ID   TSSK2_HUMAN             Reviewed;         358 AA.
AC   Q96PF2; Q8IY55;
DE   RecName: Full=Testis-specific serine/threonine-protein kinase 2;
DE            Short=TSK-2;
DE            Short=TSK2;
DE            Short=TSSK-2;
DE            Short=Testis-specific kinase 2;
DE            EC=2.7.11.1;
DE   AltName: Full=DiGeorge syndrome protein G;
DE            Short=DGS-G;
DE   AltName: Full=Serine/threonine-protein kinase 22B;
GN   Name=TSSK2; Synonyms=DGSG, SPOGA2, STK22B;
DR   GuidetoPHARMACOLOGY; 2258; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
//
ID   TSSK1_HUMAN             Reviewed;         367 AA.
AC   Q9BXA7; B2R8D9;
DE   RecName: Full=Testis-specific serine/threonine-protein kinase 1;
DE            Short=TSK-1;
DE            Short=TSK1;
DE            Short=TSSK-1;
DE            Short=Testis-specific kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Serine/threonine-protein kinase 22A;
GN   Name=TSSK1B; Synonyms=SPOGA1, SPOGA4, STK22A, STK22D, TSSK1;
GN   ORFNames=FKSG81;
DR   GuidetoPHARMACOLOGY; 2257; -.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007286; P:spermatid development; ISS:UniProtKB.
//
ID   TSSK3_HUMAN             Reviewed;         268 AA.
AC   Q96PN8; Q5TEE5;
DE   RecName: Full=Testis-specific serine/threonine-protein kinase 3;
DE            Short=TSK-3;
DE            Short=TSSK-3;
DE            Short=Testis-specific kinase 3;
DE            EC=2.7.11.1;
DE   AltName: Full=Serine/threonine-protein kinase 22C;
GN   Name=TSSK3; Synonyms=SPOGA3, STK22C;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
//
ID   TSSK4_HUMAN             Reviewed;         328 AA.
AC   Q6SA08; Q2TA60; Q6ZNM2;
DE   RecName: Full=Testis-specific serine/threonine-protein kinase 4;
DE            Short=TSK-4;
DE            Short=TSSK-4;
DE            Short=Testis-specific kinase 4;
DE            EC=2.7.11.1;
DE   AltName: Full=Serine/threonine-protein kinase 22E;
GN   Name=TSSK4; Synonyms=C14orf20, STK22E, TSSK5;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TSSK6_HUMAN             Reviewed;         273 AA.
AC   Q9BXA6; B2R9F8; Q6ZMC4; Q96LJ4;
DE   RecName: Full=Testis-specific serine/threonine-protein kinase 6;
DE            Short=TSK-6;
DE            Short=TSSK-6;
DE            Short=Testis-specific kinase 6;
DE            EC=2.7.11.1;
DE   AltName: Full=Cancer/testis antigen 72;
DE            Short=CT72;
DE   AltName: Full=Serine/threonine-protein kinase SSTK;
DE   AltName: Full=Small serine/threonine kinase;
GN   Name=TSSK6; Synonyms=SSTK; ORFNames=FKSG82;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0035092; P:sperm chromatin condensation; ISS:UniProtKB.
//
ID   TSSP_HUMAN              Reviewed;         514 AA.
AC   Q9NQE7; O75416;
DE   RecName: Full=Thymus-specific serine protease;
DE            EC=3.4.-.-;
DE   AltName: Full=Serine protease 16;
DE   Flags: Precursor;
GN   Name=PRSS16; Synonyms=TSSP;
DR   GO; GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB.
DR   GO; GO:0030163; P:protein catabolic process; NAS:UniProtKB.
//
ID   TSTD1_HUMAN             Reviewed;         115 AA.
AC   Q8NFU3; Q5SY48; Q5SY49; Q5SY50; Q5SY51; Q8NFU2; Q9BV22;
DE   RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1;
GN   Name=TSTD1; Synonyms=KAT;
//
ID   TSTD2_HUMAN             Reviewed;         516 AA.
AC   Q5T7W7; A6NMJ4; A8K584; Q6ZQZ6; Q8IYM3; Q8WY73; Q96ML6; Q96MU1;
DE   RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2;
DE   AltName: Full=Rhodanese domain-containing protein 2;
GN   Name=TSTD2; Synonyms=C9orf97; ORFNames=PP4189;
//
ID   TSTD3_HUMAN             Reviewed;          97 AA.
AC   H0UI37;
DE   RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3;
DE   AltName: Full=Rhodanese domain-containing protein 3;
GN   Name=TSTD3;
//
ID   TSY26_HUMAN             Reviewed;         355 AA.
AC   Q9H489; Q3MJ63; Q3MJ65;
DE   RecName: Full=Putative testis-specific Y-encoded-like protein 3;
DE            Short=TSPY-like protein 3;
DE   AltName: Full=Testis-specific Y-encoded protein 26 pseudogene;
GN   Name=TSPY26P; Synonyms=TSPYL3;
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   TSYL1_HUMAN             Reviewed;         437 AA.
AC   Q9H0U9; O75885; Q5TFE6;
DE   RecName: Full=Testis-specific Y-encoded-like protein 1;
DE            Short=TSPY-like protein 1;
GN   Name=TSPYL1; Synonyms=TSPYL;
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   TSYL2_HUMAN             Reviewed;         693 AA.
AC   Q9H2G4; O94799; Q96DG7; Q9BZW6;
DE   RecName: Full=Testis-specific Y-encoded-like protein 2;
DE            Short=TSPY-like protein 2;
DE   AltName: Full=Cell division autoantigen 1;
DE   AltName: Full=Cutaneous T-cell lymphoma-associated antigen se20-4;
DE            Short=CTCL-associated antigen se20-4;
DE   AltName: Full=Differentially-expressed nucleolar TGF-beta1 target protein;
DE   AltName: Full=Nuclear protein of 79 kDa;
DE            Short=NP79;
GN   Name=TSPYL2; Synonyms=CDA1, DENTT, TSPX; ORFNames=HRIHFB2216;
DR   GO; GO:0000182; F:rDNA binding; NAS:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0045786; P:negative regulation of cell cycle; NAS:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IDA:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0009966; P:regulation of signal transduction; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TSYL4_HUMAN             Reviewed;         414 AA.
AC   Q9UJ04; B4DYQ2; O94828; Q96GW8;
DE   RecName: Full=Testis-specific Y-encoded-like protein 4;
DE            Short=TSPY-like protein 4;
GN   Name=TSPYL4; Synonyms=KIAA0721;
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   TSYL5_HUMAN             Reviewed;         417 AA.
AC   Q86VY4; B3KRF0; Q9C0B3;
DE   RecName: Full=Testis-specific Y-encoded-like protein 5;
DE            Short=TSPY-like protein 5;
GN   Name=TSPYL5; Synonyms=KIAA1750;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IMP:UniProtKB.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IMP:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   TSYL6_HUMAN             Reviewed;         410 AA.
AC   Q8N831; Q6NUJ3;
DE   RecName: Full=Testis-specific Y-encoded-like protein 6;
DE            Short=TSPY-like protein 6;
GN   Name=TSPYL6;
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
//
ID   TT21A_HUMAN             Reviewed;        1320 AA.
AC   Q8NDW8; A1L388; B4DYF6; B4DYJ3; D3YTE7; D4PHA5; Q6P5W8; Q8N7G5;
AC   Q8NA02;
DE   RecName: Full=Tetratricopeptide repeat protein 21A;
DE            Short=TPR repeat protein 21A;
DE   AltName: Full=Stress-inducible protein 2;
GN   Name=TTC21A; Synonyms=STI2;
//
ID   TT21B_HUMAN             Reviewed;        1316 AA.
AC   Q7Z4L5; A8MUZ3; Q3LIE4; Q53T84; Q6P4A1; Q6PIF5; Q8NCN3; Q96MA4;
AC   Q9HAK8;
DE   RecName: Full=Tetratricopeptide repeat protein 21B;
DE            Short=TPR repeat protein 21B;
GN   Name=TTC21B; Synonyms=KIAA1992; ORFNames=Nbla10696;
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0042073; P:intraciliary transport; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:MGI.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
//
ID   TT23L_HUMAN             Reviewed;         361 AA.
AC   Q6PF05; Q6RGS4; Q8N7R3; Q96LJ2;
DE   RecName: Full=Tetratricopeptide repeat protein 23-like;
GN   Name=TTC23L;
//
ID   TT30A_HUMAN             Reviewed;         665 AA.
AC   Q86WT1; A8K8N0; Q8IVP2;
DE   RecName: Full=Tetratricopeptide repeat protein 30A;
DE            Short=TPR repeat protein 30A;
GN   Name=TTC30A;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   TT30B_HUMAN             Reviewed;         665 AA.
AC   Q8N4P2; Q63HQ1; Q96NE6;
DE   RecName: Full=Tetratricopeptide repeat protein 30B;
DE            Short=TPR repeat protein 30B;
GN   Name=TTC30B;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   TT39A_HUMAN             Reviewed;         613 AA.
AC   Q5SRH9; B7Z782; E7EQY9; O43417; O75040; Q5SRH5; Q5SRH6; Q5SRH7;
AC   Q5SRH8; Q5SRI0; Q5SRI1; Q5SRI2; Q5T7S1; Q6PIU8; Q9BT24;
DE   RecName: Full=Tetratricopeptide repeat protein 39A;
DE            Short=TPR repeat protein 39A;
DE   AltName: Full=Differentially expressed in MCF7 with estradiol protein 6;
DE            Short=DEME-6;
GN   Name=TTC39A; Synonyms=C1orf34, KIAA0452;
//
ID   TT39B_HUMAN             Reviewed;         682 AA.
AC   Q5VTQ0; A5PLN1; B4DQ10; B4DQX4; B4DW93; Q8IVR7; Q8IXZ6; Q8N267;
DE   RecName: Full=Tetratricopeptide repeat protein 39B;
DE            Short=TPR repeat protein 39B;
GN   Name=TTC39B; Synonyms=C9orf52;
//
ID   TT39C_HUMAN             Reviewed;         583 AA.
AC   Q8N584; B7WP63; J3QRR1; Q0VAJ2; Q8N284;
DE   RecName: Full=Tetratricopeptide repeat protein 39C;
DE            Short=TPR repeat protein 39C;
GN   Name=TTC39C; Synonyms=C18orf17;
//
ID   TTBK1_HUMAN             Reviewed;        1321 AA.
AC   Q5TCY1; A2A2U5; Q2L6C6; Q6ZNH0; Q8N444; Q96JH2;
DE   RecName: Full=Tau-tubulin kinase 1;
DE            EC=2.7.11.1;
DE   AltName: Full=Brain-derived tau kinase;
GN   Name=TTBK1; Synonyms=BDTK, KIAA1855;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
//
ID   TTBK2_HUMAN             Reviewed;        1244 AA.
AC   Q6IQ55; O94932; Q6ZN52; Q8IVV1;
DE   RecName: Full=Tau-tubulin kinase 2;
DE            EC=2.7.11.1;
GN   Name=TTBK2; Synonyms=KIAA0847;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0007224; P:smoothened signaling pathway; ISS:UniProtKB.
//
ID   TTC12_HUMAN             Reviewed;         705 AA.
AC   Q9H892; Q8N5H9; Q9NWY3;
DE   RecName: Full=Tetratricopeptide repeat protein 12;
DE            Short=TPR repeat protein 12;
GN   Name=TTC12;
//
ID   TTC14_HUMAN             Reviewed;         770 AA.
AC   Q96N46; G5E9X0; Q6UWJ7; Q8TF22;
DE   RecName: Full=Tetratricopeptide repeat protein 14;
DE            Short=TPR repeat protein 14;
GN   Name=TTC14; Synonyms=KIAA1980; ORFNames=UNQ5813/PRO19630;
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
//
ID   TTC13_HUMAN             Reviewed;         860 AA.
AC   Q8NBP0; B1AQI1; B1AQI2; Q8IVP8; Q8NBI0; Q8ND20;
DE   RecName: Full=Tetratricopeptide repeat protein 13;
DE            Short=TPR repeat protein 13;
GN   Name=TTC13; ORFNames=PSEC0076;
//
ID   TTC16_HUMAN             Reviewed;         873 AA.
AC   Q8NEE8; Q5JU66; Q96M72;
DE   RecName: Full=Tetratricopeptide repeat protein 16;
DE            Short=TPR repeat protein 16;
GN   Name=TTC16;
//
ID   TTC17_HUMAN             Reviewed;        1141 AA.
AC   Q96AE7;
DE   RecName: Full=Tetratricopeptide repeat protein 17;
DE            Short=TPR repeat protein 17;
GN   Name=TTC17;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; IMP:UniProtKB.
DR   GO; GO:0044782; P:cilium organization; IMP:UniProtKB.
//
ID   TTC18_HUMAN             Reviewed;        1121 AA.
AC   Q5T0N1; C9JIZ9; Q5T0M4; Q5T0M9; Q5T0N0; Q69YH9; Q8IYZ8; Q8N7D5;
AC   Q8NI30; Q8NI31;
DE   RecName: Full=Tetratricopeptide repeat protein 18;
DE            Short=TPR repeat protein 18;
GN   Name=TTC18;
//
ID   TTC19_HUMAN             Reviewed;         380 AA.
AC   Q6DKK2; A8MZ52; B3KP62; B4DN65; Q2M248; Q7L3U8; Q9H6G3; Q9NXB2;
DE   RecName: Full=Tetratricopeptide repeat protein 19, mitochondrial;
DE            Short=TPR repeat protein 19;
DE   Flags: Precursor;
GN   Name=TTC19;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000910; P:cytokinesis; TAS:UniProtKB.
DR   GO; GO:0034551; P:mitochondrial respiratory chain complex III assembly; IMP:UniProtKB.
//
ID   TTC1_HUMAN              Reviewed;         292 AA.
AC   Q99614; B2RCT2; D3DQJ8; Q9BVT3;
DE   RecName: Full=Tetratricopeptide repeat protein 1;
DE            Short=TPR repeat protein 1;
GN   Name=TTC1; Synonyms=TPR1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
//
ID   TTC22_HUMAN             Reviewed;         569 AA.
AC   Q5TAA0; Q9NWT4;
DE   RecName: Full=Tetratricopeptide repeat protein 22;
DE            Short=TPR repeat protein 22;
GN   Name=TTC22;
//
ID   TTC23_HUMAN             Reviewed;         447 AA.
AC   Q5W5X9; A8K6M5; Q53HK0; Q96BC9; Q9H8W9; Q9H9S7;
DE   RecName: Full=Tetratricopeptide repeat protein 23;
DE            Short=TPR repeat protein 23;
DE   AltName: Full=Cervical cancer proto-oncogene 8 protein;
DE            Short=HCC-8;
GN   Name=TTC23; ORFNames=HCC8;
//
ID   TTC24_HUMAN             Reviewed;         582 AA.
AC   A2A3L6; Q5T3H7;
DE   RecName: Full=Tetratricopeptide repeat protein 24;
DE            Short=TPR repeat protein 24;
GN   Name=TTC24;
//
ID   TTC25_HUMAN             Reviewed;         672 AA.
AC   Q96NG3; Q6NX40; Q6PJ04; Q9H0K5;
DE   RecName: Full=Tetratricopeptide repeat protein 25;
DE            Short=TPR repeat protein 25;
GN   Name=TTC25;
//
ID   TTC26_HUMAN             Reviewed;         554 AA.
AC   A0AVF1; A4D1S3; B7Z5M0; C9J2N7; F8W724; Q9H9S8; Q9NTC0;
DE   RecName: Full=Tetratricopeptide repeat protein 26;
DE            Short=TPR repeat protein 26;
GN   Name=TTC26;
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
//
ID   TTC27_HUMAN             Reviewed;         843 AA.
AC   Q6P3X3; A6NKJ0; Q96SS5; Q9BVF1; Q9NWR4; Q9NXG4;
DE   RecName: Full=Tetratricopeptide repeat protein 27;
DE            Short=TPR repeat protein 27;
GN   Name=TTC27;
//
ID   TTC28_HUMAN             Reviewed;        2481 AA.
AC   Q96AY4; K7ZRV2; O95928; O95929; Q5W189; Q9NTE4; Q9UG31; Q9UGG5;
AC   Q9UPV8; Q9Y3S5;
DE   RecName: Full=Tetratricopeptide repeat protein 28;
DE            Short=TPR repeat protein 28;
DE   AltName: Full=TPR repeat-containing big gene cloned at Keio;
GN   Name=TTC28; Synonyms=KIAA1043, TPRBK;
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
//
ID   TTC29_HUMAN             Reviewed;         475 AA.
AC   Q8NA56; A4GU95; Q9BXB6;
DE   RecName: Full=Tetratricopeptide repeat protein 29;
DE            Short=TPR repeat protein 29;
DE   AltName: Full=Protein TBPP2A;
DE   AltName: Full=Testis development protein NYD-SP14;
GN   Name=TTC29;
//
ID   TTC31_HUMAN             Reviewed;         519 AA.
AC   Q49AM3; Q4KN40; Q53FD4; Q9H9F7;
DE   RecName: Full=Tetratricopeptide repeat protein 31;
DE            Short=TPR repeat protein 31;
GN   Name=TTC31;
//
ID   TTC32_HUMAN             Reviewed;         151 AA.
AC   Q5I0X7;
DE   RecName: Full=Tetratricopeptide repeat protein 32;
DE            Short=TPR repeat protein 32;
GN   Name=TTC32;
//
ID   TTC33_HUMAN             Reviewed;         262 AA.
AC   Q6PID6; B2R6G0; O95105;
DE   RecName: Full=Tetratricopeptide repeat protein 33;
DE            Short=TPR repeat protein 33;
DE   AltName: Full=Osmosis-responsive factor;
GN   Name=TTC33;
//
ID   TTC34_HUMAN             Reviewed;         566 AA.
AC   A8MYJ7; A8MXL8;
DE   RecName: Full=Tetratricopeptide repeat protein 34;
DE            Short=TPR repeat protein 34;
GN   Name=TTC34;
//
ID   TTC36_HUMAN             Reviewed;         189 AA.
AC   A6NLP5; B9EJD8;
DE   RecName: Full=Tetratricopeptide repeat protein 36;
DE            Short=TPR repeat protein 36;
DE   AltName: Full=HSP70-binding protein 21;
GN   Name=TTC36; Synonyms=HBP21;
//
ID   TTC37_HUMAN             Reviewed;        1564 AA.
AC   Q6PGP7; O15077; Q6PJI3;
DE   RecName: Full=Tetratricopeptide repeat protein 37;
DE            Short=TPR repeat protein 37;
DE   AltName: Full=SKI3 homolog;
DE            Short=Ski3;
DE   AltName: Full=Tricho-hepatic-enteric syndrome protein;
DE            Short=Thespin;
GN   Name=TTC37; Synonyms=KIAA0372;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TTC38_HUMAN             Reviewed;         469 AA.
AC   Q5R3I4; Q8WV27; Q9NWP8;
DE   RecName: Full=Tetratricopeptide repeat protein 38;
DE            Short=TPR repeat protein 38;
GN   Name=TTC38;
//
ID   TTC3_HUMAN              Reviewed;        2025 AA.
AC   P53804; A8K7H7; B2RPA7; D3DSG9; D3DSH2; D3DSH3; O60767; P78476;
AC   P78477; Q569I2; Q6P578; Q9UEK4;
DE   RecName: Full=E3 ubiquitin-protein ligase TTC3;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein DCRR1;
DE   AltName: Full=RING finger protein 105;
DE   AltName: Full=TPR repeat protein D;
DE   AltName: Full=Tetratricopeptide repeat protein 3;
DE            Short=TPR repeat protein 3;
GN   Name=TTC3; Synonyms=DCRR1, RNF105, TPRD;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010771; P:negative regulation of cell morphogenesis involved in differentiation; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   TTC40_HUMAN             Reviewed;        2715 AA.
AC   Q8IYW2; B1AP44; B7WPK8; Q5JSF7; Q5SR76; Q5SR77; Q86ST2; Q8N777;
AC   Q9NTQ5;
DE   RecName: Full=Tetratricopeptide repeat protein 40;
GN   Name=TTC40; Synonyms=C10orf123, C10orf124, C10orf92, C10orf93;
//
ID   TTC4_HUMAN              Reviewed;         387 AA.
AC   O95801; Q53Y95; Q5TA96; Q9H3I2;
DE   RecName: Full=Tetratricopeptide repeat protein 4;
DE            Short=TPR repeat protein 4;
GN   Name=TTC4; ORFNames=My044;
//
ID   TTC5_HUMAN              Reviewed;         440 AA.
AC   Q8N0Z6; A8MQ18; Q96HF9;
DE   RecName: Full=Tetratricopeptide repeat protein 5;
DE            Short=TPR repeat protein 5;
DE   AltName: Full=Stress-responsive activator of p300;
DE            Short=Strap;
GN   Name=TTC5;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   TTC6_HUMAN              Reviewed;         520 AA.
AC   Q86TZ1; Q96CE6;
DE   RecName: Full=Tetratricopeptide repeat protein 6;
DE            Short=TPR repeat protein 6;
GN   Name=TTC6;
//
ID   TTC7A_HUMAN             Reviewed;         858 AA.
AC   Q9ULT0; Q6PIX4; Q8ND67; Q9BUS3;
DE   RecName: Full=Tetratricopeptide repeat protein 7A;
DE            Short=TPR repeat protein 7A;
GN   Name=TTC7A; Synonyms=KIAA1140, TTC7;
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
//
ID   TTC8_HUMAN              Reviewed;         541 AA.
AC   Q8TAM2; A6NFG2; B3KWA5; Q67B97; Q86SY0; Q86TV9; Q86U26; Q8NDH9;
AC   Q96DG8;
DE   RecName: Full=Tetratricopeptide repeat protein 8;
DE            Short=TPR repeat protein 8;
DE   AltName: Full=Bardet-Biedl syndrome 8 protein;
GN   Name=TTC8; Synonyms=BBS8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:MGI.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0060219; P:camera-type eye photoreceptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; TAS:BHF-UCL.
DR   GO; GO:0048560; P:establishment of anatomical structure orientation; IMP:BHF-UCL.
DR   GO; GO:0045444; P:fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0021772; P:olfactory bulb development; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0061326; P:renal tubule development; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:Ensembl.
DR   GO; GO:0050893; P:sensory processing; TAS:BHF-UCL.
//
ID   TTC7B_HUMAN             Reviewed;         843 AA.
AC   Q86TV6; Q86U24; Q86VT3;
DE   RecName: Full=Tetratricopeptide repeat protein 7B;
DE            Short=TPR repeat protein 7B;
DE   AltName: Full=Tetratricopeptide repeat protein 7-like-1;
DE            Short=TPR repeat protein 7-like-1;
GN   Name=TTC7B; Synonyms=TTC7L1;
//
ID   TTC9A_HUMAN             Reviewed;         222 AA.
AC   Q92623; Q86WT2;
DE   RecName: Full=Tetratricopeptide repeat protein 9A;
DE            Short=TPR repeat protein 9A;
GN   Name=TTC9; Synonyms=KIAA0227, TTC9A;
//
ID   TTC9B_HUMAN             Reviewed;         239 AA.
AC   Q8N6N2; A8K0I5; Q96NP9;
DE   RecName: Full=Tetratricopeptide repeat protein 9B;
DE            Short=TPR repeat protein 9B;
GN   Name=TTC9B;
//
ID   TTC9C_HUMAN             Reviewed;         171 AA.
AC   Q8N5M4;
DE   RecName: Full=Tetratricopeptide repeat protein 9C;
DE            Short=TPR repeat protein 9C;
GN   Name=TTC9C;
//
ID   TTF1_HUMAN              Reviewed;         905 AA.
AC   Q15361; A1L160; Q4VXF3; Q58EY2; Q6P5T5;
DE   RecName: Full=Transcription termination factor 1;
DE            Short=TTF-1;
DE   AltName: Full=RNA polymerase I termination factor;
DE   AltName: Full=Transcription termination factor I;
DE            Short=TTF-I;
GN   Name=TTF1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:Ensembl.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; NAS:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; IEA:Ensembl.
//
ID   TTF2_HUMAN              Reviewed;        1162 AA.
AC   Q9UNY4; A8K4Q2; O75921; Q5T2K7; Q5VVU8; Q8N6I8;
DE   RecName: Full=Transcription termination factor 2;
DE            EC=3.6.4.-;
DE   AltName: Full=Lodestar homolog;
DE   AltName: Full=RNA polymerase II termination factor;
DE   AltName: Full=Transcription release factor 2;
DE            Short=F2;
DE            Short=HuF2;
GN   Name=TTF2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; TAS:GOC.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; TAS:ProtInc.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:ProtInc.
//
ID   TTI1_HUMAN              Reviewed;        1089 AA.
AC   O43156; Q5JX67; Q96A38; Q9BR47; Q9H4K0;
DE   RecName: Full=TELO2-interacting protein 1 homolog;
DE   AltName: Full=Protein SMG10;
GN   Name=TTI1; Synonyms=KIAA0406, SMG10;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032006; P:regulation of TOR signaling; IMP:UniProtKB.
//
ID   TTI2_HUMAN              Reviewed;         508 AA.
AC   Q6NXR4; D3DSV7; Q96IM2; Q9H5N4;
DE   RecName: Full=TELO2-interacting protein 2;
GN   Name=TTI2; Synonyms=C8orf41;
//
ID   TTHY_HUMAN              Reviewed;         147 AA.
AC   P02766; Q549C7; Q6IB96; Q9UBZ6; Q9UCM9;
DE   RecName: Full=Transthyretin;
DE   AltName: Full=ATTR;
DE   AltName: Full=Prealbumin;
DE   AltName: Full=TBPA;
DE   Flags: Precursor;
GN   Name=TTR; Synonyms=PALB;
DR   GO; GO:0042562; F:hormone binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007603; P:phototransduction, visible light; TAS:Reactome.
DR   GO; GO:0001523; P:retinoid metabolic process; TAS:Reactome.
DR   GO; GO:0042572; P:retinol metabolic process; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   TTK_HUMAN               Reviewed;         857 AA.
AC   P33981; A8K8U5; B2RDW2; E1P543; Q15272; Q5TCS0; Q9BW51; Q9NTM0;
DE   RecName: Full=Dual specificity protein kinase TTK;
DE            EC=2.7.12.1;
DE   AltName: Full=Phosphotyrosine picked threonine-protein kinase;
DE            Short=PYT;
GN   Name=TTK; Synonyms=MPS1, MPS1L1;
DR   GuidetoPHARMACOLOGY; 2264; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
DR   GO; GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:ProtInc.
DR   GO; GO:0007052; P:mitotic spindle organization; TAS:ProtInc.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; TAS:BHF-UCL.
DR   GO; GO:0007051; P:spindle organization; TAS:ProtInc.
//
ID   TTL10_HUMAN             Reviewed;         673 AA.
AC   Q6ZVT0; B1AMF6; Q5T2W4; Q5T2W5; Q8N9X2;
DE   RecName: Full=Inactive polyglycylase TTLL10;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 10;
GN   Name=TTLL10;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   TTL11_HUMAN             Reviewed;         538 AA.
AC   Q8NHH1;
DE   RecName: Full=Tubulin polyglutamylase TTLL11;
DE            EC=6.-.-.-;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 11;
GN   Name=TTLL11; Synonyms=C9orf20;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   TTL12_HUMAN             Reviewed;         644 AA.
AC   Q14166; Q20WK5; Q9UGU3;
DE   RecName: Full=Tubulin--tyrosine ligase-like protein 12;
GN   Name=TTLL12; Synonyms=KIAA0153;
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   TTL13_HUMAN             Reviewed;         815 AA.
AC   A6NNM8;
DE   RecName: Full=Tubulin polyglutamylase TTLL13;
DE            EC=6.-.-.-;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 13;
GN   Name=TTLL13;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   TTLL1_HUMAN             Reviewed;         423 AA.
AC   O95922; B2RDS7; Q9BR27; Q9NRS9; Q9UMU0;
DE   RecName: Full=Probable tubulin polyglutamylase TTLL1;
DE            EC=6.-.-.-;
DE   AltName: Full=Tubulin polyglutamylase complex subunit 3;
DE            Short=PGs3;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 1;
GN   Name=TTLL1; Synonyms=C22orf7;
DR   GO; GO:0070740; F:tubulin-glutamic acid ligase activity; TAS:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0044782; P:cilium organization; IEA:Ensembl.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0018095; P:protein polyglutamylation; TAS:UniProtKB.
//
ID   TTLL2_HUMAN             Reviewed;         592 AA.
AC   Q9BWV7; B2RB11; B3KS77; Q7Z6R8; Q86X22;
DE   RecName: Full=Probable tubulin polyglutamylase TTLL2;
DE            EC=6.-.-.-;
DE   AltName: Full=Testis-specific protein NYD-TSPG;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 2;
GN   Name=TTLL2; Synonyms=C6orf104;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   TTLL3_HUMAN             Reviewed;         772 AA.
AC   Q9Y4R7; Q4KMS8; Q6AWA3; Q6ZU95; Q8NDN8; Q96GG8; Q9H876; Q9UI99;
DE   RecName: Full=Tubulin monoglycylase TTLL3;
DE            EC=6.3.2.-;
DE   AltName: Full=HOTTL;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 3;
GN   Name=TTLL3; ORFNames=PRO0207;
DR   GO; GO:0070735; F:protein-glycine ligase activity; IDA:UniProtKB.
DR   GO; GO:0070736; F:protein-glycine ligase activity, initiating; ISS:UniProtKB.
DR   GO; GO:0035082; P:axoneme assembly; ISS:UniProtKB.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0018094; P:protein polyglycylation; IDA:UniProtKB.
//
ID   TTLL4_HUMAN             Reviewed;        1199 AA.
AC   Q14679; A8K6V5; Q8WW29;
DE   RecName: Full=Tubulin polyglutamylase TTLL4;
DE            EC=6.-.-.-;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 4;
GN   Name=TTLL4; Synonyms=KIAA0173;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0018095; P:protein polyglutamylation; ISS:UniProtKB.
//
ID   TTLL5_HUMAN             Reviewed;        1281 AA.
AC   Q6EMB2; B9EGH8; B9EGH9; Q9BUB0; Q9H0G4; Q9H7W2; Q9P1V5; Q9UPZ4;
DE   RecName: Full=Tubulin polyglutamylase TTLL5;
DE            EC=6.-.-.-;
DE   AltName: Full=SRC1 and TIF2-associated modulatory protein;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 5;
GN   Name=TTLL5; Synonyms=KIAA0998, STAMP;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TTLL6_HUMAN             Reviewed;         843 AA.
AC   Q8N841; B4DZJ5; C9J233; Q24KB1; Q24KB2; Q24KB6; Q24KF3; Q24KJ5;
AC   Q24KN7; Q24KS9; Q24KX1; Q24L13; Q24L55; Q24L76; Q8IYW6; Q8NA62;
DE   RecName: Full=Tubulin polyglutamylase TTLL6;
DE            EC=6.-.-.-;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 6;
GN   Name=TTLL6; Synonyms=TTL.6;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015631; F:tubulin binding; ISS:UniProtKB.
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0051013; P:microtubule severing; IEA:Ensembl.
DR   GO; GO:0018095; P:protein polyglutamylation; ISS:UniProtKB.
//
ID   TTLL7_HUMAN             Reviewed;         887 AA.
AC   Q6ZT98; Q5TAX8; Q5TAX9; Q6P990; Q86YS1; Q9H5U4;
DE   RecName: Full=Tubulin polyglutamylase TTLL7;
DE            EC=6.-.-.-;
DE   AltName: Full=Testis development protein NYD-SP30;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 7;
GN   Name=TTLL7;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0018095; P:protein polyglutamylation; IEA:Ensembl.
//
ID   TTLL8_HUMAN             Reviewed;         850 AA.
AC   A6PVC2; B5MDV0;
DE   RecName: Full=Protein monoglycylase TTLL8;
DE            EC=6.3.2.-;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 8;
GN   Name=TTLL8;
DR   GO; GO:0070735; F:protein-glycine ligase activity; ISS:UniProtKB.
DR   GO; GO:0070736; F:protein-glycine ligase activity, initiating; ISS:UniProtKB.
DR   GO; GO:0018094; P:protein polyglycylation; ISS:UniProtKB.
//
ID   TTLL9_HUMAN             Reviewed;         439 AA.
AC   Q3SXZ7; A6NH06; A6NIS5; B3KSG8; Q3SXZ8; Q5JYS3; Q5JYS4;
DE   RecName: Full=Probable tubulin polyglutamylase TTLL9;
DE            EC=6.-.-.-;
DE   AltName: Full=Tubulin--tyrosine ligase-like protein 9;
GN   Name=TTLL9; Synonyms=C20orf125;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
//
ID   TTL_HUMAN               Reviewed;         377 AA.
AC   Q8NG68; Q585T3; Q7Z302; Q8N426;
DE   RecName: Full=Tubulin--tyrosine ligase;
DE            Short=TTL;
DE            EC=6.3.2.25;
GN   Name=TTL;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004835; F:tubulin-tyrosine ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0030516; P:regulation of axon extension; IEA:Ensembl.
//
ID   TTMP_HUMAN              Reviewed;         217 AA.
AC   Q5BVD1; B4DNV2; B4E0Z2; Q96AJ4; Q9H5Q1;
DE   RecName: Full=TPA-induced transmembrane protein;
GN   Name=TTMP; Synonyms=C3orf52;
//
ID   TTPAL_HUMAN             Reviewed;         342 AA.
AC   Q9BTX7; E1P5X3; Q5QPC1; Q9H1G2; Q9NQG8;
DE   RecName: Full=Alpha-tocopherol transfer protein-like;
GN   Name=TTPAL; Synonyms=C20orf121;
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
//
ID   TTPA_HUMAN              Reviewed;         278 AA.
AC   P49638; Q71V64;
DE   RecName: Full=Alpha-tocopherol transfer protein;
DE            Short=Alpha-TTP;
GN   Name=TTPA; Synonyms=TPP1;
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:UniProtKB.
DR   GO; GO:0005215; F:transporter activity; IEA:InterPro.
DR   GO; GO:0008431; F:vitamin E binding; ISS:UniProtKB.
DR   GO; GO:0001892; P:embryonic placenta development; IEA:Ensembl.
DR   GO; GO:0046909; P:intermembrane transport; ISS:UniProtKB.
DR   GO; GO:0051452; P:intracellular pH reduction; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0090212; P:negative regulation of establishment of blood-brain barrier; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0009268; P:response to pH; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0042360; P:vitamin E metabolic process; IEA:Ensembl.
DR   GO; GO:0051180; P:vitamin transport; ISS:UniProtKB.
//
ID   TTP_HUMAN               Reviewed;         326 AA.
AC   P26651; B2RA54;
DE   RecName: Full=Tristetraprolin;
DE            Short=TTP;
DE   AltName: Full=G0/G1 switch regulatory protein 24;
DE   AltName: Full=Growth factor-inducible nuclear protein NUP475;
DE   AltName: Full=Protein TIS11A;
DE            Short=TIS11;
DE   AltName: Full=Zinc finger protein 36 homolog;
DE            Short=Zfp-36;
GN   Name=ZFP36; Synonyms=G0S24, RNF162A, TIS11A, TTP;
DR   GO; GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.
DR   GO; GO:0017091; F:AU-rich element binding; IDA:UniProtKB.
DR   GO; GO:0019957; F:C-C chemokine binding; IPI:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003729; F:mRNA binding; IDA:MGI.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0003727; F:single-stranded RNA binding; TAS:ProtInc.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006402; P:mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0035278; P:negative regulation of translation involved in gene silencing by miRNA; ISS:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:UniProtKB.
DR   GO; GO:1900153; P:positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.
DR   GO; GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:UniProtKB.
DR   GO; GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.
DR   GO; GO:0042594; P:response to starvation; IDA:UniProtKB.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
//
ID   TTY10_HUMAN             Reviewed;          68 AA.
AC   Q9BZA0;
DE   RecName: Full=Putative transcript Y 10 protein;
GN   Name=TTTY10; Synonyms=TTY10;
//
ID   TTY12_HUMAN             Reviewed;          90 AA.
AC   Q9BZ98;
DE   RecName: Full=Putative transcript Y 12 protein;
GN   Name=TTTY12; Synonyms=TTY12;
//
ID   TTY13_HUMAN             Reviewed;          58 AA.
AC   Q9BZ97;
DE   RecName: Full=Putative transcript Y 13 protein;
GN   Name=TTTY13; Synonyms=TTY13;
//
ID   TTYH1_HUMAN             Reviewed;         450 AA.
AC   Q9H313; B0VJY3; B0VJY4; B0VJY5; B2VAL9; Q5U682; Q68A17; Q6L750;
AC   Q6ZTE5; Q8WUU2;
DE   RecName: Full=Protein tweety homolog 1;
DE            Short=hTTY1;
GN   Name=TTYH1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:Ensembl.
DR   GO; GO:0005381; F:iron ion transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0072320; F:volume-sensitive chloride channel activity; IDA:FlyBase.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0031589; P:cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0006821; P:chloride transport; IDA:FlyBase.
DR   GO; GO:0046847; P:filopodium assembly; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0034755; P:iron ion transmembrane transport; NAS:GOC.
DR   GO; GO:0006826; P:iron ion transport; NAS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0044070; P:regulation of anion transport; IDA:GOC.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TTYH2_HUMAN             Reviewed;         534 AA.
AC   Q9BSA4; B3KX97; Q3B7H8; Q3B7R9; Q6AWB4; Q8NBB7; Q96PK1;
DE   RecName: Full=Protein tweety homolog 2;
DE            Short=hTTY2;
GN   Name=TTYH2; Synonyms=C17orf29;
DR   GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   TTYH3_HUMAN             Reviewed;         523 AA.
AC   Q9C0H2; A4D201; B7WP98; Q6L749; Q6ZVG3; Q8TEG6;
DE   RecName: Full=Protein tweety homolog 3;
DE            Short=hTTY3;
GN   Name=TTYH3; Synonyms=KIAA1691;
DR   GO; GO:0005254; F:chloride channel activity; IMP:UniProtKB.
DR   GO; GO:0005229; F:intracellular calcium activated chloride channel activity; IDA:FlyBase.
DR   GO; GO:1902476; P:chloride transmembrane transport; IDA:GOC.
DR   GO; GO:0006821; P:chloride transport; IDA:FlyBase.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   TUB_HUMAN               Reviewed;         506 AA.
AC   P50607; D3DQU4; O00293; Q6B007;
DE   RecName: Full=Tubby protein homolog;
GN   Name=TUB;
DR   GO; GO:0008020; F:G-protein coupled photoreceptor activity; IEA:Ensembl.
DR   GO; GO:0044259; P:multicellular organismal macromolecule metabolic process; IEA:Ensembl.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0007602; P:phototransduction; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
//
ID   TUFT1_HUMAN             Reviewed;         390 AA.
AC   Q9NNX1; B2RD57; D3DV21; D3DV22; Q5T384; Q5T385; Q9BU28; Q9H5L1;
DE   RecName: Full=Tuftelin;
GN   Name=TUFT1;
DR   GO; GO:0030345; F:structural constituent of tooth enamel; NAS:UniProtKB.
DR   GO; GO:0030282; P:bone mineralization; NAS:UniProtKB.
DR   GO; GO:0042476; P:odontogenesis; NAS:UniProtKB.
//
ID   TUFT_HUMAN              Reviewed;           4 AA.
AC   P01858;
DE   RecName: Full=Phagocytosis-stimulating peptide;
DE   AltName: Full=Tuftsin;
//
ID   TULP2_HUMAN             Reviewed;         520 AA.
AC   O00295; Q8TC50;
DE   RecName: Full=Tubby-related protein 2;
DE   AltName: Full=Cancer/testis antigen 65;
DE            Short=CT65;
DE   AltName: Full=Tubby-like protein 2;
GN   Name=TULP2; Synonyms=TUBL2;
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   TULP1_HUMAN             Reviewed;         542 AA.
AC   O00294; O43536; Q5TGM5; Q8N571;
DE   RecName: Full=Tubby-related protein 1;
DE   AltName: Full=Tubby-like protein 1;
GN   Name=TULP1; Synonyms=TUBL1;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0008020; F:G-protein coupled photoreceptor activity; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016358; P:dendrite development; ISS:UniProtKB.
DR   GO; GO:0050908; P:detection of light stimulus involved in visual perception; IMP:UniProt.
DR   GO; GO:0042462; P:eye photoreceptor cell development; ISS:UniProtKB.
DR   GO; GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; ISS:UniProtKB.
DR   GO; GO:0007602; P:phototransduction; IEA:Ensembl.
DR   GO; GO:0050766; P:positive regulation of phagocytosis; IDA:UniProtKB.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0001895; P:retina homeostasis; IMP:UniProt.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   TULP3_HUMAN             Reviewed;         442 AA.
AC   O75386; B3KNB7; D3DUQ4; F8WBZ9; Q8N5B0;
DE   RecName: Full=Tubby-related protein 3;
DE   AltName: Full=Tubby-like protein 3;
GN   Name=TULP3; Synonyms=TUBL3;
DR   GO; GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0060434; P:bronchus morphogenesis; IEA:Ensembl.
DR   GO; GO:0021953; P:central nervous system neuron differentiation; IEA:Ensembl.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048702; P:embryonic neurocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; NAS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0021914; P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
//
ID   TULP4_HUMAN             Reviewed;        1543 AA.
AC   Q9NRJ4; Q5T3M2; Q5T3M3; Q9HD22; Q9P2F0;
DE   RecName: Full=Tubby-related protein 4;
DE   AltName: Full=Tubby superfamily protein;
DE   AltName: Full=Tubby-like protein 4;
GN   Name=TULP4; Synonyms=KIAA1397, TUBL4, TUSP;
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0007584; P:response to nutrient; TAS:ProtInc.
//
ID   TUSC1_HUMAN             Reviewed;         212 AA.
AC   Q2TAM9; A0PJ78; Q67GI3; Q86SS1; Q8TAH8;
DE   RecName: Full=Tumor suppressor candidate gene 1 protein;
DE   AltName: Full=TSG-9;
DE            Short=TSG9;
GN   Name=TUSC1;
//
ID   TUSC2_HUMAN             Reviewed;         110 AA.
AC   O75896; B2R4Y9;
DE   RecName: Full=Tumor suppressor candidate 2;
DE   AltName: Full=Fusion 1 protein;
DE            Short=Fus-1 protein;
DE   AltName: Full=PDGFA-associated protein 2;
GN   Name=TUSC2; Synonyms=C3orf11, FUS1, LGCC, PDAP2;
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0071609; P:chemokine (C-C motif) ligand 5 production; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0032618; P:interleukin-15 production; IEA:Ensembl.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0051881; P:regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IEA:Ensembl.
//
ID   TUSC3_HUMAN             Reviewed;         348 AA.
AC   Q13454; A8MSM0; D3DSP2; Q14911; Q14912; Q96FW0;
DE   RecName: Full=Tumor suppressor candidate 3;
DE   AltName: Full=Magnesium uptake/transporter TUSC3;
DE   AltName: Full=Protein N33;
DE   Flags: Precursor;
GN   Name=TUSC3; Synonyms=N33;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0050890; P:cognition; IMP:UniProtKB.
DR   GO; GO:0015693; P:magnesium ion transport; IGI:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006487; P:protein N-linked glycosylation; NAS:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; ISS:UniProtKB.
//
ID   TUSC5_HUMAN             Reviewed;         177 AA.
AC   Q8IXB3; A6NMK4;
DE   RecName: Full=Tumor suppressor candidate 5;
DE   AltName: Full=Dispanin subfamily B member 1;
DE            Short=DSPB1;
DE   AltName: Full=Interferon-induced transmembrane domain-containing protein D3;
DE   AltName: Full=Protein located at seventeen-p-thirteen point three 1;
GN   Name=TUSC5; Synonyms=IFITMD3, LOST1;
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:InterPro.
//
ID   TUT4_HUMAN              Reviewed;        1644 AA.
AC   Q5TAX3; A2RRP0; B7Z8J5; D3DQ35; Q12764; Q5TAX2; Q5TAX4; Q86XZ3;
DE   RecName: Full=Terminal uridylyltransferase 4;
DE            Short=TUTase 4;
DE            EC=2.7.7.52;
DE   AltName: Full=Zinc finger CCHC domain-containing protein 11;
GN   Name=ZCCHC11; Synonyms=KIAA0191, TUT4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050265; F:RNA uridylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001816; P:cytokine production; IEA:Ensembl.
DR   GO; GO:0070102; P:interleukin-6-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0010587; P:miRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0010586; P:miRNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0031054; P:pre-miRNA processing; IMP:UniProtKB.
DR   GO; GO:0031664; P:regulation of lipopolysaccharide-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0031123; P:RNA 3'-end processing; IDA:UniProtKB.
DR   GO; GO:0019827; P:stem cell maintenance; IMP:UniProtKB.
//
ID   TUT7_HUMAN              Reviewed;        1495 AA.
AC   Q5VYS8; Q5H9T0; Q5VYS5; Q5VYS7; Q658Z9; Q659A2; Q6MZJ3; Q8N5F0;
AC   Q96N57; Q96NE8; Q9C0F2; Q9H8M6;
DE   RecName: Full=Terminal uridylyltransferase 7;
DE            Short=TUTase 7;
DE            EC=2.7.7.52;
DE   AltName: Full=Zinc finger CCHC domain-containing protein 6;
GN   Name=ZCCHC6; Synonyms=HS2, KIAA1711, TUT7;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0050265; F:RNA uridylyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031123; P:RNA 3'-end processing; IDA:UniProtKB.
//
ID   TUTLA_HUMAN             Reviewed;        1179 AA.
AC   Q9P2J2;
DE   RecName: Full=Protein turtle homolog A;
DE   AltName: Full=Immunoglobulin superfamily member 9A;
DE            Short=IgSF9A;
DE   Flags: Precursor;
GN   Name=IGSF9; Synonyms=IGSF9A, KIAA1355, NRT1;
DR   GO; GO:0016358; P:dendrite development; IEA:Ensembl.
//
ID   TUTLB_HUMAN             Reviewed;        1349 AA.
AC   Q9UPX0; G5EA26;
DE   RecName: Full=Protein turtle homolog B;
DE   AltName: Full=Immunoglobulin superfamily member 9B;
DE            Short=IgSF9B;
DE   Flags: Precursor;
GN   Name=IGSF9B; Synonyms=KIAA1030;
//
ID   TV23A_HUMAN             Reviewed;         213 AA.
AC   A6NH52; B2RUV4; B7ZW18;
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog A;
GN   Name=TVP23A; Synonyms=FAM18A;
//
ID   TV23B_HUMAN             Reviewed;         205 AA.
AC   Q9NYZ1; A8K448; Q96HK5; Q9Y3E6;
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog B;
GN   Name=TVP23B; Synonyms=FAM18B, FAM18B1; ORFNames=CGI-148, NPD008;
//
ID   TV23C_HUMAN             Reviewed;         276 AA.
AC   Q96ET8; Q3LIC7;
DE   RecName: Full=Golgi apparatus membrane protein TVP23 homolog C;
GN   Name=TVP23C; Synonyms=FAM18B2; ORFNames=Nbla10383;
//
ID   TVA1_HUMAN              Reviewed;         131 AA.
AC   P04436;
DE   RecName: Full=T-cell receptor alpha chain V region HPB-MLT;
DE   Flags: Precursor; Fragment;
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TVA2_HUMAN              Reviewed;         139 AA.
AC   P04437;
DE   RecName: Full=T-cell receptor alpha chain V region CTL-L17;
DE   Flags: Precursor;
GN   Name=TCRA;
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TVA3_HUMAN              Reviewed;         135 AA.
AC   P01737;
DE   RecName: Full=T-cell receptor alpha chain V region PY14;
DE   Flags: Precursor;
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TVB2_HUMAN              Reviewed;         133 AA.
AC   P04435;
DE   RecName: Full=T-cell receptor beta chain V region CTL-L17;
DE   Flags: Precursor;
GN   Name=TCRB;
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TVB1_HUMAN              Reviewed;         135 AA.
AC   P01733; A0A5A7;
DE   RecName: Full=T-cell receptor beta chain V region YT35;
DE   Flags: Precursor;
GN   Name=TRBV12-3; Synonyms=TCRBV8S1;
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   TVC_HUMAN               Reviewed;         136 AA.
AC   P03979;
DE   RecName: Full=T-cell receptor gamma chain V region PT-gamma-1/2;
DE   Flags: Precursor;
GN   Name=TRGV3; Synonyms=TCRB;
DR   GO; GO:0042287; F:MHC protein binding; NAS:UniProtKB.
DR   GO; GO:0042605; F:peptide antigen binding; NAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; NAS:UniProtKB.
//
ID   TWF1_HUMAN              Reviewed;         350 AA.
AC   Q12792; A8K5A8; B3KXS6; B4DLX9; Q59G07; Q5U0B1; Q6FHJ1; Q6FHL6;
AC   Q6NUK9; Q86XL6; Q8TCD3;
DE   RecName: Full=Twinfilin-1;
DE   AltName: Full=Protein A6;
DE   AltName: Full=Protein tyrosine kinase 9;
GN   Name=TWF1; Synonyms=PTK9;
DR   GO; GO:0003785; F:actin monomer binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IDA:BHF-UCL.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IEA:Ensembl.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; ISS:BHF-UCL.
DR   GO; GO:0043538; P:regulation of actin phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL.
//
ID   TWF2_HUMAN              Reviewed;         349 AA.
AC   Q6IBS0; Q9Y3F5;
DE   RecName: Full=Twinfilin-2;
DE   AltName: Full=A6-related protein;
DE            Short=hA6RP;
DE   AltName: Full=Protein tyrosine kinase 9-like;
DE   AltName: Full=Twinfilin-1-like protein;
GN   Name=TWF2; Synonyms=PTK9L; ORFNames=MSTP011;
DR   GO; GO:0003785; F:actin monomer binding; ISS:BHF-UCL.
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.
DR   GO; GO:0051016; P:barbed-end actin filament capping; ISS:BHF-UCL.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.
DR   GO; GO:0030837; P:negative regulation of actin filament polymerization; ISS:BHF-UCL.
DR   GO; GO:0045773; P:positive regulation of axon extension; IMP:BHF-UCL.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IMP:BHF-UCL.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IMP:BHF-UCL.
DR   GO; GO:0032532; P:regulation of microvillus length; IC:BHF-UCL.
DR   GO; GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL.
//
ID   TWSG1_HUMAN             Reviewed;         223 AA.
AC   Q9GZX9; B2RE08; D3DUH9; Q8NBI7; Q96K46;
DE   RecName: Full=Twisted gastrulation protein homolog 1;
DE   Flags: Precursor;
GN   Name=TWSG1; Synonyms=TSG; ORFNames=PSEC0250;
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; IEA:Ensembl.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IEA:Ensembl.
//
ID   TWST1_HUMAN             Reviewed;         202 AA.
AC   Q15672; A4D128; Q92487; Q99804;
DE   RecName: Full=Twist-related protein 1;
DE   AltName: Full=Class A basic helix-loop-helix protein 38;
DE            Short=bHLHa38;
DE   AltName: Full=H-twist;
GN   Name=TWIST1; Synonyms=BHLHA38, TWIST;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0070888; F:E-box binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0003180; P:aortic valve morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0003253; P:cardiac neural crest cell migration involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:2000793; P:cell proliferation involved in heart valve development; IMP:BHF-UCL.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0060363; P:cranial suture morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0060900; P:embryonic camera-type eye formation; IMP:BHF-UCL.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0003203; P:endocardial cushion morphogenesis; IEA:Ensembl.
DR   GO; GO:0061029; P:eyelid development in camera-type eye; IMP:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0003183; P:mitral valve morphogenesis; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:2000773; P:negative regulation of cellular senescence; IMP:BHF-UCL.
DR   GO; GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.
DR   GO; GO:2000780; P:negative regulation of double-strand break repair; IMP:BHF-UCL.
DR   GO; GO:0035067; P:negative regulation of histone acetylation; IEA:Ensembl.
DR   GO; GO:0033128; P:negative regulation of histone phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:2000276; P:negative regulation of oxidative phosphorylation uncoupler activity; IEA:Ensembl.
DR   GO; GO:0035359; P:negative regulation of peroxisome proliferator activated receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0014067; P:negative regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0042476; P:odontogenesis; IEA:Ensembl.
DR   GO; GO:0001503; P:ossification; TAS:BHF-UCL.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0042473; P:outer ear morphogenesis; TAS:BHF-UCL.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; NAS:BHF-UCL.
DR   GO; GO:2000147; P:positive regulation of cell motility; IMP:BHF-UCL.
DR   GO; GO:2000802; P:positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation; IEA:Ensembl.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.
DR   GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:2000778; P:positive regulation of interleukin-6 secretion; IMP:BHF-UCL.
DR   GO; GO:0071639; P:positive regulation of monocyte chemotactic protein-1 production; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IMP:BHF-UCL.
DR   GO; GO:0032760; P:positive regulation of tumor necrosis factor production; IMP:BHF-UCL.
DR   GO; GO:0030500; P:regulation of bone mineralization; IMP:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:GOC.
//
ID   TWST2_HUMAN             Reviewed;         160 AA.
AC   Q8WVJ9; Q3SYL6;
DE   RecName: Full=Twist-related protein 2;
DE   AltName: Full=Class A basic helix-loop-helix protein 39;
DE            Short=bHLHa39;
DE   AltName: Full=Dermis-expressed protein 1;
DE            Short=Dermo-1;
GN   Name=TWIST2; Synonyms=BHLHA39, DERMO1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0061303; P:cornea development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0060325; P:face morphogenesis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IEA:Ensembl.
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0010838; P:positive regulation of keratinocyte proliferation; IEA:Ensembl.
//
ID   TX101_HUMAN             Reviewed;         249 AA.
AC   Q9BY14; Q7L5R2; Q9BPY7;
DE   RecName: Full=Testis-expressed sequence 101 protein;
DE   AltName: Full=Cell surface receptor NYD-SP8;
DE   AltName: Full=Scleroderma-associated autoantigen;
DE   AltName: Full=Spermatogenesis-related gene protein;
DE   Flags: Precursor;
GN   Name=TEX101; Synonyms=SGRG; ORFNames=UNQ867/PRO1884;
//
ID   TX13B_HUMAN             Reviewed;         312 AA.
AC   Q9BXU2; Q5JYF6;
DE   RecName: Full=Testis-expressed sequence 13B protein;
GN   Name=TEX13B;
//
ID   TX13A_HUMAN             Reviewed;         409 AA.
AC   Q9BXU3; B1B1G8; Q32NB6;
DE   RecName: Full=Testis-expressed sequence 13A protein;
GN   Name=TEX13A;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   TX1B3_HUMAN             Reviewed;         124 AA.
AC   O14907; B2RD53; D3DTJ6; Q7LCQ4;
DE   RecName: Full=Tax1-binding protein 3;
DE   AltName: Full=Glutaminase-interacting protein 3;
DE   AltName: Full=Tax interaction protein 1;
DE            Short=TIP-1;
DE   AltName: Full=Tax-interacting protein 1;
GN   Name=TAX1BP3; Synonyms=TIP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0032864; P:activation of Cdc42 GTPase activity; IDA:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   TX261_HUMAN             Reviewed;         196 AA.
AC   Q6UWH6; A1A587; D6W5G9; Q8WUJ5;
DE   RecName: Full=Protein TEX261;
GN   Name=TEX261; ORFNames=UNQ1882/PRO4325;
//
ID   TX264_HUMAN             Reviewed;         313 AA.
AC   Q9Y6I9; B3KN87; Q9UKD7;
DE   RecName: Full=Testis-expressed sequence 264 protein;
DE   AltName: Full=Putative secreted protein Zsig11;
DE   Flags: Precursor;
GN   Name=TEX264; Synonyms=ZSIG11; ORFNames=UNQ337/PRO536;
//
ID   TXD11_HUMAN             Reviewed;         985 AA.
AC   Q6PKC3; O95887; Q6PJA6; Q8N2Q4; Q96K45; Q96K53;
DE   RecName: Full=Thioredoxin domain-containing protein 11;
DE   AltName: Full=EF-hand-binding protein 1;
GN   Name=TXNDC11; Synonyms=EFP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   TXD12_HUMAN             Reviewed;         172 AA.
AC   O95881; B3KQS0; Q5T1T4; Q96H50;
DE   RecName: Full=Thioredoxin domain-containing protein 12;
DE            EC=1.8.4.2;
DE   AltName: Full=Endoplasmic reticulum resident protein 18;
DE            Short=ER protein 18;
DE            Short=ERp18;
DE   AltName: Full=Endoplasmic reticulum resident protein 19;
DE            Short=ER protein 19;
DE            Short=ERp19;
DE   AltName: Full=Thioredoxin-like protein p19;
DE   AltName: Full=hTLP19;
DE   Flags: Precursor;
GN   Name=TXNDC12; Synonyms=TLP19; ORFNames=UNQ713/PRO1376;
DR   GO; GO:0019153; F:protein-disulfide reductase (glutathione) activity; IEA:UniProtKB-EC.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   TXD15_HUMAN             Reviewed;         360 AA.
AC   Q96J42; D3DQA9; Q96MT2; Q9H639;
DE   RecName: Full=Thioredoxin domain-containing protein 15;
DE   Flags: Precursor;
GN   Name=TXNDC15; Synonyms=C5orf14; ORFNames=UNQ335/PRO534;
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   TXD16_HUMAN             Reviewed;         825 AA.
AC   Q9P2K2; A5PKW9; A7E260; A7MD07; B9EH67; Q9H9W7;
DE   RecName: Full=Thioredoxin domain-containing protein 16;
DE   Flags: Precursor;
GN   Name=TXNDC16; Synonyms=KIAA1344;
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   TXD17_HUMAN             Reviewed;         123 AA.
AC   Q9BRA2; A8K7E8;
DE   RecName: Full=Thioredoxin domain-containing protein 17;
DE   AltName: Full=14 kDa thioredoxin-related protein;
DE            Short=TRP14;
DE   AltName: Full=Protein 42-9-9;
DE   AltName: Full=Thioredoxin-like protein 5;
GN   Name=TXNDC17; Synonyms=TXNL5;
DR   GO; GO:0009055; F:electron carrier activity; IDA:UniProtKB.
DR   GO; GO:0004601; F:peroxidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047134; F:protein-disulfide reductase activity; IDA:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.
//
ID   TXIP1_HUMAN             Reviewed;         658 AA.
AC   Q2TAA8; Q9P105;
DE   RecName: Full=Translin-associated factor X-interacting protein 1;
DE            Short=Trax-interacting protein 1;
GN   Name=TSNAXIP1; Synonyms=TXI1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TXK_HUMAN               Reviewed;         527 AA.
AC   P42681; Q14220;
DE   RecName: Full=Tyrosine-protein kinase TXK;
DE            EC=2.7.10.2;
DE   AltName: Full=Protein-tyrosine kinase 4;
DE   AltName: Full=Resting lymphocyte kinase;
GN   Name=TXK; Synonyms=PTK4, RLK;
DR   GuidetoPHARMACOLOGY; 2268; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0001012; F:RNA polymerase II regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; ISS:UniProtKB.
DR   GO; GO:0001816; P:cytokine production; ISS:UniProtKB.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032633; P:interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0001865; P:NK T cell differentiation; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0060335; P:positive regulation of interferon-gamma-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TXLNA_HUMAN             Reviewed;         546 AA.
AC   P40222; D3DPP6; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86;
AC   Q86YW3; Q8N2Y3;
DE   RecName: Full=Alpha-taxilin;
GN   Name=TXLNA; Synonyms=TXLN;
DR   GO; GO:0005125; F:cytokine activity; NAS:UniProtKB.
DR   GO; GO:0030372; F:high molecular weight B cell growth factor receptor binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0042113; P:B cell activation; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; NAS:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
//
ID   TXLNB_HUMAN             Reviewed;         684 AA.
AC   Q8N3L3; Q5VTF3; Q76L25; Q86T52; Q8N3S2;
DE   RecName: Full=Beta-taxilin;
DE   AltName: Full=Muscle-derived protein 77;
DE            Short=hMDP77;
GN   Name=TXLNB; Synonyms=C6orf198, MDP77;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   TXLNG_HUMAN             Reviewed;         528 AA.
AC   Q9NUQ3; Q2KQ75; Q5JNZ7; Q9P0X1;
DE   RecName: Full=Gamma-taxilin;
DE   AltName: Full=Environmental lipopolysaccharide-responding gene protein;
DE   AltName: Full=Factor inhibiting ATF4-mediated transcription;
DE            Short=FIAT;
DE   AltName: Full=Lipopolysaccharide-specific response protein 5;
GN   Name=TXLNG; Synonyms=CXorf15, ELRG, LSR5;
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030500; P:regulation of bone mineralization; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:0010564; P:regulation of cell cycle process; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TXN4A_HUMAN             Reviewed;         142 AA.
AC   P83876; B2RC18; O14834;
DE   RecName: Full=Thioredoxin-like protein 4A;
DE   AltName: Full=DIM1 protein homolog;
DE   AltName: Full=Spliceosomal U5 snRNP-specific 15 kDa protein;
DE   AltName: Full=Thioredoxin-like U5 snRNP protein U5-15kD;
GN   Name=TXNL4A; Synonyms=DIM1, TXNL4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; TAS:UniProtKB.
DR   GO; GO:0000245; P:spliceosomal complex assembly; TAS:UniProtKB.
//
ID   TXN4B_HUMAN             Reviewed;         149 AA.
AC   Q9NX01; D3DWS6;
DE   RecName: Full=Thioredoxin-like protein 4B;
DE   AltName: Full=Dim1-like protein;
GN   Name=TXNL4B; Synonyms=DIM2, DLP;
DR   GO; GO:0007067; P:mitosis; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   TXND2_HUMAN             Reviewed;         553 AA.
AC   Q86VQ3; A5YM73; Q8N7U4; Q96RX3; Q9H0L8;
DE   RecName: Full=Thioredoxin domain-containing protein 2;
DE   AltName: Full=Spermatid-specific thioredoxin-1;
DE            Short=Sptrx-1;
GN   Name=TXNDC2; Synonyms=SPTRX, SPTRX1;
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:InterPro.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IEA:Ensembl.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   TXND3_HUMAN             Reviewed;         588 AA.
AC   Q8N427; Q9NZH1;
DE   RecName: Full=Thioredoxin domain-containing protein 3;
DE   AltName: Full=NM23-H8;
DE   AltName: Full=NME/NM23 family member 8;
DE   AltName: Full=Spermatid-specific thioredoxin-2;
DE            Short=Sptrx-2;
GN   Name=NME8; Synonyms=SPTRX2, TXNDC3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   TXND5_HUMAN             Reviewed;         432 AA.
AC   Q8NBS9; B2RDM2; Q5TCQ0; Q8ND33; Q8TCT2; Q9BVH9;
DE   RecName: Full=Thioredoxin domain-containing protein 5;
DE   AltName: Full=Endoplasmic reticulum resident protein 46;
DE            Short=ER protein 46;
DE            Short=ERp46;
DE   AltName: Full=Thioredoxin-like protein p46;
DE   Flags: Precursor;
GN   Name=TXNDC5; Synonyms=TLP46; ORFNames=UNQ364/PRO700;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003756; F:protein disulfide isomerase activity; IBA:RefGenome.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0043277; P:apoptotic cell clearance; IBA:RefGenome.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; IBA:RefGenome.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:RefGenome.
//
ID   TXND6_HUMAN             Reviewed;         330 AA.
AC   Q86XW9; Q7Z4A8; Q8N1V7;
DE   RecName: Full=Thioredoxin domain-containing protein 6;
DE   AltName: Full=Thioredoxin-like protein 2;
DE            Short=Txl-2;
GN   Name=NME9; Synonyms=TXL2, TXNDC6;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
//
ID   TXND8_HUMAN             Reviewed;         127 AA.
AC   Q6A555; A1L4I2; A6NDK7; Q5T934;
DE   RecName: Full=Thioredoxin domain-containing protein 8;
DE   AltName: Full=Spermatid-specific thioredoxin-3;
DE            Short=Sptrx-3;
DE   AltName: Full=Thioredoxin-6;
GN   Name=TXNDC8; Synonyms=SPTRX3, TRX6;
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   TXND9_HUMAN             Reviewed;         226 AA.
AC   O14530; B2R9G8; D3DVI4; Q53HG4; Q53RV8; Q6NSF5; Q9BRU6;
DE   RecName: Full=Thioredoxin domain-containing protein 9;
DE   AltName: Full=ATP-binding protein associated with cell differentiation;
DE   AltName: Full=Protein 1-4;
GN   Name=TXNDC9; Synonyms=APACD;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
//
ID   TXNG2_HUMAN             Reviewed;         131 AA.
AC   Q9BZA5;
DE   RecName: Full=Putative gamma-taxilin 2;
DE   AltName: Full=Gamma-taxilin 2 pseudogene;
GN   Name=TXLNG2P; Synonyms=CYorf15A, CYorf15B;
//
ID   TXNIP_HUMAN             Reviewed;         391 AA.
AC   Q9H3M7; B4E3D3; Q16226; Q6PML0; Q9BXG9;
DE   RecName: Full=Thioredoxin-interacting protein;
DE   AltName: Full=Thioredoxin-binding protein 2;
DE   AltName: Full=Vitamin D3 up-regulated protein 1;
GN   Name=TXNIP; Synonyms=VDUP1;
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0071228; P:cellular response to tumor cell; IDA:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030216; P:keratinocyte differentiation; IDA:UniProtKB.
DR   GO; GO:0051782; P:negative regulation of cell division; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0042542; P:response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0009612; P:response to mechanical stimulus; IEA:Ensembl.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   TXNL1_HUMAN             Reviewed;         289 AA.
AC   O43396;
DE   RecName: Full=Thioredoxin-like protein 1;
DE   AltName: Full=32 kDa thioredoxin-related protein;
GN   Name=TXNL1; Synonyms=TRP32, TXL, TXNL;
DR   GO; GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.
DR   GO; GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IEA:InterPro.
DR   GO; GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
//
ID   TXTP_HUMAN              Reviewed;         311 AA.
AC   P53007; A8K8E8; Q9BSK6;
DE   RecName: Full=Tricarboxylate transport protein, mitochondrial;
DE   AltName: Full=Citrate transport protein;
DE            Short=CTP;
DE   AltName: Full=Solute carrier family 25 member 1;
DE   AltName: Full=Tricarboxylate carrier protein;
DE   Flags: Precursor;
GN   Name=SLC25A1; Synonyms=SLC20A3;
DR   GuidetoPHARMACOLOGY; 1051; -.
DR   GO; GO:0015137; F:citrate transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0015746; P:citrate transport; TAS:GOC.
DR   GO; GO:0006094; P:gluconeogenesis; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
//
ID   TY3H_HUMAN              Reviewed;         528 AA.
AC   P07101; B7ZL70; B7ZL73; Q0PWM2; Q0PWM3; Q15585; Q15588; Q15589;
AC   Q2M3B4;
DE   RecName: Full=Tyrosine 3-monooxygenase;
DE            EC=1.14.16.2;
DE   AltName: Full=Tyrosine 3-hydroxylase;
DE            Short=TH;
GN   Name=TH; Synonyms=TYH;
DR   GuidetoPHARMACOLOGY; 1243; -.
DR   GO; GO:0016597; F:amino acid binding; IEA:Ensembl.
DR   GO; GO:0035240; F:dopamine binding; IEA:Ensembl.
DR   GO; GO:0008199; F:ferric iron binding; IEA:Ensembl.
DR   GO; GO:0008198; F:ferrous iron binding; IEA:Ensembl.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0019825; F:oxygen binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0034617; F:tetrahydrobiopterin binding; IEA:Ensembl.
DR   GO; GO:0004511; F:tyrosine 3-monooxygenase activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0009072; P:aromatic amino acid family metabolic process; IEA:InterPro.
DR   GO; GO:0042423; P:catecholamine biosynthetic process; TAS:Reactome.
DR   GO; GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0071287; P:cellular response to manganese ion; IEA:Ensembl.
DR   GO; GO:0071316; P:cellular response to nicotine; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0042745; P:circadian sleep/wake cycle; IEA:Ensembl.
DR   GO; GO:0042416; P:dopamine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0006585; P:dopamine biosynthetic process from tyrosine; NAS:BHF-UCL.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0042418; P:epinephrine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0042462; P:eye photoreceptor cell development; ISS:BHF-UCL.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0016137; P:glycoside metabolic process; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; NAS:BHF-UCL.
DR   GO; GO:0033076; P:isoquinoline alkaloid metabolic process; IEA:Ensembl.
DR   GO; GO:0007612; P:learning; ISS:BHF-UCL.
DR   GO; GO:0007626; P:locomotory behavior; ISS:BHF-UCL.
DR   GO; GO:0007617; P:mating behavior; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; ISS:BHF-UCL.
DR   GO; GO:0010259; P:multicellular organismal aging; IEA:Ensembl.
DR   GO; GO:0042136; P:neurotransmitter biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0042421; P:norepinephrine biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0009887; P:organ morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0018963; P:phthalate metabolic process; IEA:Ensembl.
DR   GO; GO:0052314; P:phytoalexin metabolic process; IEA:Ensembl.
DR   GO; GO:0043473; P:pigmentation; TAS:BHF-UCL.
DR   GO; GO:0008016; P:regulation of heart contraction; ISS:BHF-UCL.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IDA:BHF-UCL.
DR   GO; GO:0045472; P:response to ether; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IDA:BHF-UCL.
DR   GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0043434; P:response to peptide hormone; IEA:Ensembl.
DR   GO; GO:0046684; P:response to pyrethroid; IEA:Ensembl.
DR   GO; GO:0009651; P:response to salt stress; IEA:Ensembl.
DR   GO; GO:0009414; P:response to water deprivation; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:Ensembl.
DR   GO; GO:0001963; P:synaptic transmission, dopaminergic; ISS:BHF-UCL.
DR   GO; GO:0015842; P:synaptic vesicle amine transport; IEA:Ensembl.
DR   GO; GO:0042214; P:terpene metabolic process; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; ISS:BHF-UCL.
//
ID   TYB10_HUMAN             Reviewed;          44 AA.
AC   P63313; P13472; Q596K9;
DE   RecName: Full=Thymosin beta-10;
GN   Name=TMSB10; Synonyms=PTMB10, THYB10;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0042989; P:sequestering of actin monomers; IEA:InterPro.
//
ID   TYB4Y_HUMAN             Reviewed;          44 AA.
AC   O14604; Q0VDA2;
DE   RecName: Full=Thymosin beta-4, Y-chromosomal;
GN   Name=TMSB4Y; Synonyms=TB4Y;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; TAS:ProtInc.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0042989; P:sequestering of actin monomers; TAS:ProtInc.
//
ID   TYB4_HUMAN              Reviewed;          44 AA.
AC   P62328; P01253; P01254; Q546P5; Q63576; Q9UE55;
DE   RecName: Full=Thymosin beta-4;
DE            Short=T beta-4;
DE   AltName: Full=Fx;
DE   Contains:
DE     RecName: Full=Hematopoietic system regulatory peptide;
DE     AltName: Full=Seraspenide;
GN   Name=TMSB4X; Synonyms=TB4X, THYB4, TMSB4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0042989; P:sequestering of actin monomers; IEA:InterPro.
//
ID   TYDP1_HUMAN             Reviewed;         608 AA.
AC   Q9NUW8; Q2HXX4; Q96BK7; Q9NZM7; Q9NZM8;
DE   RecName: Full=Tyrosyl-DNA phosphodiesterase 1;
DE            Short=Tyr-DNA phosphodiesterase 1;
DE            EC=3.1.4.-;
GN   Name=TDP1;
DR   GO; GO:0017005; F:3'-tyrosyl-DNA phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0000012; P:single strand break repair; IDA:UniProtKB.
//
ID   TYDP2_HUMAN             Reviewed;         362 AA.
AC   O95551; B4DKL8; B4DQ95; Q2TBE2; Q5JYM0; Q7Z6U5; Q9NUK5; Q9NYY9;
DE   RecName: Full=Tyrosyl-DNA phosphodiesterase 2;
DE            Short=Tyr-DNA phosphodiesterase 2;
DE            Short=hTDP2;
DE            EC=3.1.4.-;
DE   AltName: Full=5'-tyrosyl-DNA phosphodiesterase;
DE            Short=5'-Tyr-DNA phosphodiesterase;
DE   AltName: Full=ETS1-associated protein 2;
DE   AltName: Full=ETS1-associated protein II;
DE            Short=EAPII;
DE   AltName: Full=TRAF and TNF receptor-associated protein;
DE   AltName: Full=Tyrosyl-RNA phosphodiesterase;
DE   AltName: Full=VPg unlinkase;
GN   Name=TDP2; Synonyms=EAP2, TTRAP; ORFNames=AD-022;
DR   GO; GO:0070260; F:5'-tyrosyl-DNA phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0036317; F:tyrosyl-RNA phosphodiesterase activity; IDA:UniProtKB.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:2001141; P:regulation of RNA biosynthetic process; TAS:GOC.
//
ID   TYK2_HUMAN              Reviewed;        1187 AA.
AC   P29597; Q6QB10; Q96CH0;
DE   RecName: Full=Non-receptor tyrosine-protein kinase TYK2;
DE            EC=2.7.10.2;
GN   Name=TYK2;
DR   GuidetoPHARMACOLOGY; 2269; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005131; F:growth hormone receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   TYOBP_HUMAN             Reviewed;         113 AA.
AC   O43914; A8K2X0; F5H389; Q6FGA5; Q9UMT3;
DE   RecName: Full=TYRO protein tyrosine kinase-binding protein;
DE   AltName: Full=DNAX-activation protein 12;
DE   AltName: Full=Killer-activating receptor-associated protein;
DE            Short=KAR-associated protein;
DE   Flags: Precursor;
GN   Name=TYROBP; Synonyms=DAP12, KARAP;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0005057; F:receptor signaling protein activity; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
DR   GO; GO:0002281; P:macrophage activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0002283; P:neutrophil activation involved in immune response; IEA:Ensembl.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:2001204; P:regulation of osteoclast development; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   TYPH_HUMAN              Reviewed;         482 AA.
AC   P19971; A8MW15; H9KVA0; Q13390; Q8WVB7;
DE   RecName: Full=Thymidine phosphorylase;
DE            Short=TP;
DE            EC=2.4.2.4;
DE   AltName: Full=Gliostatin;
DE   AltName: Full=Platelet-derived endothelial cell growth factor;
DE            Short=PD-ECGF;
DE   AltName: Full=TdRPase;
DE   Flags: Precursor;
GN   Name=TYMP; Synonyms=ECGF1;
DR   GO; GO:0004645; F:phosphorylase activity; IEA:InterPro.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; TAS:ProtInc.
DR   GO; GO:0016154; F:pyrimidine-nucleoside phosphorylase activity; IEA:InterPro.
DR   GO; GO:0009032; F:thymidine phosphorylase activity; TAS:ProtInc.
DR   GO; GO:0016763; F:transferase activity, transferring pentosyl groups; EXP:Reactome.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; TAS:ProtInc.
DR   GO; GO:0000002; P:mitochondrial genome maintenance; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0006220; P:pyrimidine nucleotide metabolic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   TYRO3_HUMAN             Reviewed;         890 AA.
AC   Q06418; O14953; Q86VR3;
DE   RecName: Full=Tyrosine-protein kinase receptor TYRO3;
DE            EC=2.7.10.1;
DE   AltName: Full=Tyrosine-protein kinase BYK;
DE   AltName: Full=Tyrosine-protein kinase DTK;
DE   AltName: Full=Tyrosine-protein kinase RSE;
DE   AltName: Full=Tyrosine-protein kinase SKY;
DE   AltName: Full=Tyrosine-protein kinase TIF;
DE   Flags: Precursor;
GN   Name=TYRO3; Synonyms=BYK, DTK, RSE, SKY, TIF;
DR   GuidetoPHARMACOLOGY; 1836; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; NAS:UniProtKB.
DR   GO; GO:0043277; P:apoptotic cell clearance; ISS:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; NAS:UniProtKB.
DR   GO; GO:0021885; P:forebrain cell migration; ISS:UniProtKB.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0045824; P:negative regulation of innate immune response; ISS:UniProtKB.
DR   GO; GO:0051250; P:negative regulation of lymphocyte activation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0034122; P:negative regulation of toll-like receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0070050; P:neuron cellular homeostasis; ISS:UniProtKB.
DR   GO; GO:0042698; P:ovulation cycle; ISS:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:GOC.
DR   GO; GO:0014065; P:phosphatidylinositol 3-kinase signaling; NAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; ISS:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0043491; P:protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0032940; P:secretion by cell; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; NAS:GOC.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   TYRO_HUMAN              Reviewed;         529 AA.
AC   P14679; Q15675; Q15676; Q15680; Q8TAK4; Q9BYY0; Q9BZX1;
DE   RecName: Full=Tyrosinase;
DE            EC=1.14.18.1;
DE   AltName: Full=LB24-AB;
DE   AltName: Full=Monophenol monooxygenase;
DE   AltName: Full=SK29-AB;
DE   AltName: Full=Tumor rejection antigen AB;
DE   Flags: Precursor;
GN   Name=TYR;
DR   GuidetoPHARMACOLOGY; 2643; -.
DR   GO; GO:0005507; F:copper ion binding; IMP:UniProtKB.
DR   GO; GO:0004503; F:monophenol monooxygenase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0006726; P:eye pigment biosynthetic process; TAS:ProtInc.
DR   GO; GO:0006583; P:melanin biosynthetic process from tyrosine; TAS:ProtInc.
DR   GO; GO:0048538; P:thymus development; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   TYRP1_HUMAN             Reviewed;         537 AA.
AC   P17643; P78468; P78469; Q13721; Q15679;
DE   RecName: Full=5,6-dihydroxyindole-2-carboxylic acid oxidase;
DE            Short=DHICA oxidase;
DE            EC=1.14.18.-;
DE   AltName: Full=Catalase B;
DE   AltName: Full=Glycoprotein 75;
DE   AltName: Full=Melanoma antigen gp75;
DE   AltName: Full=Tyrosinase-related protein 1;
DE            Short=TRP;
DE            Short=TRP-1;
DE            Short=TRP1;
DE   Flags: Precursor;
GN   Name=TYRP1; Synonyms=CAS2, TYRP, TYRRP;
DR   GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR   GO; GO:0016716; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0043438; P:acetoacetic acid metabolic process; IEA:Ensembl.
DR   GO; GO:0042438; P:melanin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
DR   GO; GO:0032438; P:melanosome organization; IEA:Ensembl.
//
ID   TYRP2_HUMAN             Reviewed;         519 AA.
AC   P40126; Q09GT4;
DE   RecName: Full=L-dopachrome tautomerase;
DE            Short=DCT;
DE            Short=DT;
DE            EC=5.3.3.12;
DE   AltName: Full=L-dopachrome Delta-isomerase;
DE   AltName: Full=Tyrosinase-related protein 2;
DE            Short=TRP-2;
DE            Short=TRP2;
DE   Flags: Precursor;
GN   Name=DCT; Synonyms=TYRP2;
DR   GO; GO:0005507; F:copper ion binding; TAS:ProtInc.
DR   GO; GO:0004167; F:dopachrome isomerase activity; ISS:UniProtKB.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0048468; P:cell development; IEA:Ensembl.
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0006583; P:melanin biosynthetic process from tyrosine; ISS:UniProtKB.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0021847; P:ventricular zone neuroblast division; IEA:Ensembl.
//
ID   TYSD1_HUMAN             Reviewed;         566 AA.
AC   Q2T9J0; Q5SQT4; Q5SQU1; Q8N6H2; Q96AR5;
DE   RecName: Full=Peroxisomal leader peptide-processing protease;
DE            EC=3.4.21.-;
DE   AltName: Full=Trypsin domain-containing protein 1;
DE   Contains:
DE     RecName: Full=Peroxisomal leader peptide-processing protease, 15 kDa form;
DE   Contains:
DE     RecName: Full=Peroxisomal leader peptide-processing protease, 45 kDa form;
GN   Name=TYSND1;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0016485; P:protein processing; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IMP:UniProtKB.
DR   GO; GO:0031998; P:regulation of fatty acid beta-oxidation; IMP:UniProtKB.
//
ID   TYSY_HUMAN              Reviewed;         313 AA.
AC   P04818; Q8WYK3; Q8WYK4;
DE   RecName: Full=Thymidylate synthase;
DE            Short=TS;
DE            Short=TSase;
DE            EC=2.1.1.45;
GN   Name=TYMS; Synonyms=TS; ORFNames=OK/SW-cl.29;
DR   GuidetoPHARMACOLOGY; 2642; -.
DR   GO; GO:0048037; F:cofactor binding; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0005542; F:folic acid binding; IEA:Ensembl.
DR   GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR   GO; GO:0000166; F:nucleotide binding; IEA:Ensembl.
DR   GO; GO:0004799; F:thymidylate synthase activity; TAS:Reactome.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0007623; P:circadian rhythm; IEA:Ensembl.
DR   GO; GO:0009157; P:deoxyribonucleoside monophosphate biosynthetic process; TAS:ProtInc.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; NAS:UniProtKB.
DR   GO; GO:0006260; P:DNA replication; NAS:UniProtKB.
DR   GO; GO:0006231; P:dTMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006235; P:dTTP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046078; P:dUMP metabolic process; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0019088; P:immortalization of host cell by virus; IEA:Ensembl.
DR   GO; GO:0060574; P:intestinal epithelial cell maturation; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0005976; P:polysaccharide metabolic process; IEA:Ensembl.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
DR   GO; GO:0000083; P:regulation of transcription involved in G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0046683; P:response to organophosphorus; IEP:UniProtKB.
DR   GO; GO:0032570; P:response to progesterone; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0033189; P:response to vitamin A; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:Ensembl.
DR   GO; GO:0019860; P:uracil metabolic process; IEA:Ensembl.
//
ID   TYW1B_HUMAN             Reviewed;         668 AA.
AC   Q6NUM6; A6NG09; Q3KQX2;
DE   RecName: Full=S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase;
DE            EC=4.1.3.44;
DE   AltName: Full=Radical S-adenosyl methionine and flavodoxin domain-containing protein 2;
DE   AltName: Full=tRNA wybutosine-synthesizing protein 1 homolog B;
GN   Name=TYW1B; Synonyms=RSAFD2;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TYW1_HUMAN              Reviewed;         732 AA.
AC   Q9NV66; Q6PJG8; Q75MG8; Q75MN3; Q86V12; Q8IVS7; Q9H9C4;
DE   RecName: Full=S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase;
DE            EC=4.1.3.44;
DE   AltName: Full=Radical S-adenosyl methionine and flavodoxin domain-containing protein 1;
DE   AltName: Full=tRNA wybutosine-synthesizing protein 1 homolog;
DE   AltName: Full=tRNA-yW-synthesizing protein;
GN   Name=TYW1; Synonyms=RSAFD1;
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TYW2_HUMAN              Reviewed;         448 AA.
AC   Q53H54; Q6PKB9; Q96F21; Q9NWK6;
DE   RecName: Full=tRNA wybutosine-synthesizing protein 2 homolog;
DE            Short=tRNA-yW-synthesizing protein 2;
DE            EC=2.1.1.-;
DE   AltName: Full=Alpha-amino-alpha-carboxypropyl transferase TYW2;
DE            EC=2.5.1.-;
GN   Name=TRMT12; Synonyms=TRM12, TYW2;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TYW3_HUMAN              Reviewed;         259 AA.
AC   Q6IPR3; B4DSP9; E9PGR7; Q5HYJ0; Q8N7L1;
DE   RecName: Full=tRNA wybutosine-synthesizing protein 3 homolog;
DE            EC=2.1.1.282;
DE   AltName: Full=tRNA-yW-synthesizing protein 3;
GN   Name=TYW3; Synonyms=C1orf171;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TYW4_HUMAN              Reviewed;         686 AA.
AC   O60294; Q4JFT6; Q96B55; Q9NR10;
DE   RecName: Full=tRNA wybutosine-synthesizing protein 4;
DE            Short=tRNA yW-synthesizing protein 4;
DE            EC=2.1.1.290;
DE            EC=2.3.1.231;
DE   AltName: Full=Leucine carboxyl methyltransferase 2;
DE   AltName: Full=tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase;
DE   AltName: Full=tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase;
GN   Name=LCMT2; Synonyms=KIAA0547, TYW4;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
//
ID   TYW5_HUMAN              Reviewed;         315 AA.
AC   A2RUC4; B2RNE3; Q8N1R2;
DE   RecName: Full=tRNA wybutosine-synthesizing protein 5;
DE            Short=hTYW5;
DE            EC=1.14.11.42;
DE   AltName: Full=tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase;
GN   Name=TYW5; Synonyms=C2orf60;
DR   GO; GO:0005506; F:iron ion binding; IDA:UniProtKB.
DR   GO; GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0031591; P:wybutosine biosynthetic process; IDA:UniProtKB.
//
ID   TYY1_HUMAN              Reviewed;         414 AA.
AC   P25490; Q14935;
DE   RecName: Full=Transcriptional repressor protein YY1;
DE   AltName: Full=Delta transcription factor;
DE   AltName: Full=INO80 complex subunit S;
DE   AltName: Full=NF-E1;
DE   AltName: Full=Yin and yang 1;
DE            Short=YY-1;
GN   Name=YY1; Synonyms=INO80S;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0000400; F:four-way junction DNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:MGI.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IMP:UniProtKB.
DR   GO; GO:0051276; P:chromosome organization; IEA:Ensembl.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0034696; P:response to prostaglandin F; IEA:Ensembl.
DR   GO; GO:0010225; P:response to UV-C; IMP:UniProtKB.
DR   GO; GO:0006403; P:RNA localization; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   TYY2_HUMAN              Reviewed;         372 AA.
AC   O15391; B2RP10; Q6Q1S4;
DE   RecName: Full=Transcription factor YY2;
DE   AltName: Full=Yin and yang 2;
DE            Short=YY-2;
DE   AltName: Full=Zinc finger protein 631;
GN   Name=YY2; Synonyms=ZNF631;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   U119A_HUMAN             Reviewed;         240 AA.
AC   Q13432; A8K8G4; F1T095; O95126;
DE   RecName: Full=Protein unc-119 homolog A;
DE   AltName: Full=Retinal protein 4;
DE            Short=hRG4;
GN   Name=UNC119; Synonyms=RG4;
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007109; P:cytokinesis, completion of separation; IMP:UniProtKB.
DR   GO; GO:0042953; P:lipoprotein transport; IDA:UniProtKB.
DR   GO; GO:2001287; P:negative regulation of caveolin-mediated endocytosis; ISS:UniProtKB.
DR   GO; GO:1900186; P:negative regulation of clathrin-mediated endocytosis; ISS:UniProtKB.
DR   GO; GO:0007602; P:phototransduction; TAS:ProtInc.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   U119B_HUMAN             Reviewed;         251 AA.
AC   A6NIH7;
DE   RecName: Full=Protein unc-119 homolog B;
GN   Name=UNC119B;
DR   GO; GO:0008289; F:lipid binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.
DR   GO; GO:0042953; P:lipoprotein transport; IDA:UniProtKB.
//
ID   U17L1_HUMAN             Reviewed;         530 AA.
AC   Q7RTZ2;
DE   RecName: Full=Putative ubiquitin carboxyl-terminal hydrolase 17-like protein 1;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 17-like protein 1;
DE   AltName: Full=Ubiquitin thioesterase 17-like protein 1;
DE   AltName: Full=Ubiquitin-specific-processing protease 17-like protein 1;
GN   Name=USP17L1P; Synonyms=USP17L, USP17L1;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L2_HUMAN             Reviewed;         530 AA.
AC   Q6R6M4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17;
DE            Short=USP17;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 17-like protein 2;
DE   AltName: Full=Deubiquitinating protein 3;
DE            Short=DUB-3;
DE   AltName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 2;
DE   AltName: Full=Ubiquitin thioesterase 17-like protein 2;
DE   AltName: Full=Ubiquitin-specific-processing protease 17-like protein 2;
GN   Name=USP17L2;
GN   Synonyms=DUB3, USP17, USP17H, USP17I, USP17J, USP17K, USP17L, USP17M;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071586; P:CAAX-box protein processing; IMP:UniProtKB.
DR   GO; GO:0000075; P:cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
DR   GO; GO:0031064; P:negative regulation of histone deacetylation; IMP:UniProtKB.
DR   GO; GO:0010955; P:negative regulation of protein processing; IMP:UniProtKB.
DR   GO; GO:0090315; P:negative regulation of protein targeting to membrane; IMP:UniProtKB.
DR   GO; GO:0034261; P:negative regulation of Ras GTPase activity; IDA:UniProtKB.
DR   GO; GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IMP:UniProtKB.
DR   GO; GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0030334; P:regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0050691; P:regulation of defense response to virus by host; IMP:UniProtKB.
DR   GO; GO:1900027; P:regulation of ruffle assembly; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L3_HUMAN             Reviewed;         530 AA.
AC   A6NCW0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 3;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 17-like protein 3;
DE   AltName: Full=Ubiquitin thioesterase 17-like protein 3;
DE   AltName: Full=Ubiquitin-specific-processing protease 17-like protein 3;
GN   Name=USP17L3; Synonyms=USP17B, USP17F;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L5_HUMAN             Reviewed;         530 AA.
AC   A8MUK1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 5;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 17-like protein 5;
DE   AltName: Full=Ubiquitin thioesterase 17-like protein 5;
DE   AltName: Full=Ubiquitin-specific-processing protease 17-like protein 5;
GN   Name=USP17L5;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L4_HUMAN             Reviewed;         530 AA.
AC   A6NCW7;
DE   RecName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4;
GN   Name=USP17L4;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L7_HUMAN             Reviewed;         530 AA.
AC   P0C7H9;
DE   RecName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7;
GN   Name=USP17L7;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L6_HUMAN             Reviewed;         398 AA.
AC   Q6QN14;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 6;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 17-like protein 6;
DE   AltName: Full=Ubiquitin thioesterase 17-like protein 6;
DE   AltName: Full=Ubiquitin-specific-processing protease 17-like protein 6;
GN   Name=USP17L6P; Synonyms=USP17C, USP17D, USP17N;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17L8_HUMAN             Reviewed;         530 AA.
AC   P0C7I0;
DE   RecName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8;
GN   Name=USP17L8;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LA_HUMAN             Reviewed;         530 AA.
AC   C9JJH3;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 10;
DE            EC=3.4.19.12;
GN   Name=USP17L10;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LD_HUMAN             Reviewed;         530 AA.
AC   C9JLJ4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 13;
DE            EC=3.4.19.12;
GN   Name=USP17L13;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LB_HUMAN             Reviewed;         530 AA.
AC   C9JVI0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 11;
DE            EC=3.4.19.12;
GN   Name=USP17L11;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LH_HUMAN             Reviewed;         530 AA.
AC   D6RBQ6;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 17;
DE            EC=3.4.19.12;
GN   Name=USP17L17;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LI_HUMAN             Reviewed;         530 AA.
AC   D6R9N7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 18;
DE            EC=3.4.19.12;
GN   Name=USP17L18;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LF_HUMAN             Reviewed;         530 AA.
AC   C9J2P7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 15;
DE            EC=3.4.19.12;
GN   Name=USP17L15;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LK_HUMAN             Reviewed;         530 AA.
AC   D6RJB6;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 20;
DE            EC=3.4.19.12;
GN   Name=USP17L20;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LJ_HUMAN             Reviewed;         530 AA.
AC   D6RCP7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 19;
DE            EC=3.4.19.12;
GN   Name=USP17L19;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LM_HUMAN             Reviewed;         530 AA.
AC   D6RA61;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 22;
DE            EC=3.4.19.12;
GN   Name=USP17L22;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LL_HUMAN             Reviewed;         530 AA.
AC   D6R901;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 21;
DE            EC=3.4.19.12;
GN   Name=USP17L21;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LO_HUMAN             Reviewed;         530 AA.
AC   Q0WX57; A8MRA9; Q0WX56; Q3BEM1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 24;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 17;
DE   AltName: Full=Ubiquitin thioesterase 17;
DE   AltName: Full=Ubiquitin-specific-processing protease 17;
GN   Name=USP17L24;
GN   Synonyms=USP17, USP17H, USP17I, USP17J, USP17K, USP17L, USP17M;
GN   and
GN   Name=USP17L25;
GN   and
GN   Name=USP17L26;
GN   and
GN   Name=USP17L27;
GN   and
GN   Name=USP17L28;
GN   and
GN   Name=USP17L29;
GN   and
GN   Name=USP17L30;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U17LN_HUMAN             Reviewed;         183 AA.
AC   D6RBM5;
DE   RecName: Full=Putative ubiquitin carboxyl-terminal hydrolase 17-like protein 23;
GN   Name=USP17L23;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   U1SBP_HUMAN             Reviewed;         246 AA.
AC   Q16560; A8K262; Q5XKN9;
DE   RecName: Full=U11/U12 small nuclear ribonucleoprotein 35 kDa protein;
DE            Short=U11/U12 snRNP 35 kDa protein;
DE            Short=U11/U12-35K;
DE   AltName: Full=Protein HM-1;
DE   AltName: Full=U1 snRNP-binding protein homolog;
GN   Name=SNRNP35; Synonyms=HM1, U1SNRNPBP;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   U2AF1_HUMAN             Reviewed;         240 AA.
AC   Q01081; Q701P4; Q71RF1;
DE   RecName: Full=Splicing factor U2AF 35 kDa subunit;
DE   AltName: Full=U2 auxiliary factor 35 kDa subunit;
DE   AltName: Full=U2 small nuclear RNA auxiliary factor 1;
DE   AltName: Full=U2 snRNP auxiliary factor small subunit;
GN   Name=U2AF1; Synonyms=U2AF35, U2AFBP; ORFNames=FP793;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   U2AF2_HUMAN             Reviewed;         475 AA.
AC   P26368; Q96HC5;
DE   RecName: Full=Splicing factor U2AF 65 kDa subunit;
DE   AltName: Full=U2 auxiliary factor 65 kDa subunit;
DE            Short=hU2AF(65);
DE            Short=hU2AF65;
DE   AltName: Full=U2 snRNP auxiliary factor large subunit;
GN   Name=U2AF2; Synonyms=U2AF65;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006406; P:mRNA export from nucleus; TAS:Reactome.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:HGNC.
DR   GO; GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   U2AF4_HUMAN             Reviewed;         220 AA.
AC   Q8WU68; A6NKI8; Q56UU3;
DE   RecName: Full=Splicing factor U2AF 26 kDa subunit;
DE   AltName: Full=U2 auxiliary factor 26;
DE   AltName: Full=U2 small nuclear RNA auxiliary factor 1-like protein 4;
DE   AltName: Full=U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3;
DE            Short=U2 small nuclear RNA auxiliary factor 1-like protein 3;
DE            Short=U2AF1-like protein 3;
GN   Name=U2AF1L4; Synonyms=U2AF1-RS3, U2AF1L3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   U2AFL_HUMAN             Reviewed;         479 AA.
AC   Q15695; B2R901; Q13570; Q2M3R8;
DE   RecName: Full=U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1;
DE   AltName: Full=CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 1;
DE   AltName: Full=U2(RNU2) small nuclear RNA auxiliary factor 1-like 1;
GN   Name=ZRSR1; Synonyms=U2AF1-RS1, U2AF1L1, U2AF1P, U2AF1RS1, U2AFBPL;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
//
ID   U2AFM_HUMAN             Reviewed;         482 AA.
AC   Q15696; Q14D69;
DE   RecName: Full=U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2;
DE   AltName: Full=CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2;
DE   AltName: Full=Renal carcinoma antigen NY-REN-20;
DE   AltName: Full=U2(RNU2) small nuclear RNA auxiliary factor 1-like 2;
DE   AltName: Full=U2AF35-related protein;
DE            Short=URP;
GN   Name=ZRSR2; Synonyms=U2AF1-RS2, U2AF1L2, U2AF1RS2, URP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0030628; F:pre-mRNA 3'-splice site binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
DR   GO; GO:0000245; P:spliceosomal complex assembly; IMP:UniProtKB.
//
ID   U2D2L_HUMAN             Reviewed;          75 AA.
AC   Q8IWF7;
DE   RecName: Full=Putative ubiquitin-conjugating enzyme E2 D2-like protein;
DE   AltName: Full=Ubiquitin carrier protein D2-like;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2D N-terminal-like;
DE   AltName: Full=Ubiquitin-protein ligase D2-like;
GN   Name=UBE2DNL; Synonyms=UBE2D2L;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
//
ID   U2QL1_HUMAN             Reviewed;         161 AA.
AC   A1L167;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2Q-like protein 1;
DE            EC=6.3.2.19;
GN   Name=UBE2QL1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
//
ID   U2Q2L_HUMAN             Reviewed;         131 AA.
AC   H0YL09;
DE   RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;
GN   Name=UBE2Q2L;
//
ID   U3IP2_HUMAN             Reviewed;         475 AA.
AC   O43818; B2R996; Q8IZ30;
DE   RecName: Full=U3 small nucleolar RNA-interacting protein 2;
DE   AltName: Full=RRP9 homolog;
DE   AltName: Full=U3 small nucleolar ribonucleoprotein-associated 55 kDa protein;
DE            Short=U3 snoRNP-associated 55 kDa protein;
DE            Short=U3-55K;
GN   Name=RRP9; Synonyms=RNU3IP2, U355K;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; TAS:ProtInc.
//
ID   U520_HUMAN              Reviewed;        2136 AA.
AC   O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0;
DE   RecName: Full=U5 small nuclear ribonucleoprotein 200 kDa helicase;
DE            EC=3.6.4.13;
DE   AltName: Full=Activating signal cointegrator 1 complex subunit 3-like 1;
DE   AltName: Full=BRR2 homolog;
DE   AltName: Full=U5 snRNP-specific 200 kDa protein;
DE            Short=U5-200KD;
GN   Name=SNRNP200; Synonyms=ASCC3L1, HELIC2, KIAA0788;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IDA:HGNC.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0000354; P:cis assembly of pre-catalytic spliceosome; IC:HGNC.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   U5S1_HUMAN              Reviewed;         972 AA.
AC   Q15029; B4DK30; D3DX58; Q9BUR0;
DE   RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component;
DE   AltName: Full=Elongation factor Tu GTP-binding domain-containing protein 2;
DE   AltName: Full=SNU114 homolog;
DE            Short=hSNU114;
DE   AltName: Full=U5 snRNP-specific protein, 116 kDa;
DE            Short=U5-116 kDa;
GN   Name=EFTUD2; Synonyms=KIAA0031, SNRP116;
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006184; P:GTP catabolic process; TAS:GOC.
DR   GO; GO:0006397; P:mRNA processing; TAS:ProtInc.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
//
ID   U633A_HUMAN             Reviewed;          94 AA.
AC   A6NN06; A1A4A6; B7WNL3; Q96BV1;
DE   RecName: Full=Putative UPF0633 protein MGC21881;
//
ID   U633B_HUMAN             Reviewed;          94 AA.
AC   Q5VV11;
DE   RecName: Full=Putative UPF0633 protein ENSP00000303136;
//
ID   U633C_HUMAN             Reviewed;          94 AA.
AC   Q5XG85;
DE   RecName: Full=Putative UPF0633 protein LOC554249;
//
ID   U730_HUMAN              Reviewed;          51 AA.
AC   Q86TS7;
DE   RecName: Full=UPF0730 protein LINC00643;
DE   AltName: Full=Long intergenic non-protein coding RNA 643;
GN   Name=LINC00643;
//
ID   UACA_HUMAN              Reviewed;        1416 AA.
AC   Q9BZF9; G3XAG2; Q14DD3; Q8N3B8; Q96NH6; Q9HCL1; Q9NWC6;
DE   RecName: Full=Uveal autoantigen with coiled-coil domains and ankyrin repeats;
GN   Name=UACA; Synonyms=KIAA1561;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0050728; P:negative regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
//
ID   UAP1L_HUMAN             Reviewed;         507 AA.
AC   Q3KQV9; A2AMJ8; Q5SPZ2; Q69YQ3; Q6ZR38;
DE   RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase-like protein 1;
DE            EC=2.7.7.-;
GN   Name=UAP1L1;
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
//
ID   UAP1_HUMAN              Reviewed;         522 AA.
AC   Q16222; B2R6R8; Q5VTA9; Q5VTB0; Q5VTB1; Q96GM2;
DE   RecName: Full=UDP-N-acetylhexosamine pyrophosphorylase;
DE   AltName: Full=Antigen X;
DE            Short=AGX;
DE   AltName: Full=Sperm-associated antigen 2;
DE   Includes:
DE     RecName: Full=UDP-N-acetylgalactosamine pyrophosphorylase;
DE              EC=2.7.7.83;
DE     AltName: Full=AGX-1;
DE   Includes:
DE     RecName: Full=UDP-N-acetylglucosamine pyrophosphorylase;
DE              EC=2.7.7.23;
DE     AltName: Full=AGX-2;
GN   Name=UAP1; Synonyms=SPAG2;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:Ensembl.
DR   GO; GO:0003977; F:UDP-N-acetylglucosamine diphosphorylase activity; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006488; P:dolichol-linked oligosaccharide biosynthetic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; TAS:Reactome.
//
ID   UB2D1_HUMAN             Reviewed;         147 AA.
AC   P51668; A6NLF6; A8K786;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 D1;
DE            EC=6.3.2.19;
DE   AltName: Full=Stimulator of Fe transport;
DE            Short=SFT;
DE   AltName: Full=UBC4/5 homolog;
DE   AltName: Full=UbcH5;
DE   AltName: Full=Ubiquitin carrier protein D1;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2(17)KB 1;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-17 kDa 1;
DE   AltName: Full=Ubiquitin-protein ligase D1;
GN   Name=UBE2D1; Synonyms=SFT, UBC5A, UBCH5, UBCH5A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   UB2D2_HUMAN             Reviewed;         147 AA.
AC   P62837; D3DQC9; P51669; Q3MN78; Q96RP6;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 D2;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein D2;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2(17)KB 2;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-17 kDa 2;
DE   AltName: Full=Ubiquitin-protein ligase D2;
DE   AltName: Full=p53-regulated ubiquitin-conjugating enzyme 1;
GN   Name=UBE2D2; Synonyms=PUBC1, UBC4, UBC5B, UBCH4, UBCH5B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UB2D3_HUMAN             Reviewed;         147 AA.
AC   P61077; A6NJ93; A6NJB1; A6NM99; P47986; Q6IB88; Q6NXS4; Q8N924;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 D3;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein D3;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2(17)KB 3;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-17 kDa 3;
DE   AltName: Full=Ubiquitin-protein ligase D3;
GN   Name=UBE2D3; Synonyms=UBC5C, UBCH5C;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UB2E1_HUMAN             Reviewed;         193 AA.
AC   P51965; B2RBX4; C9J8K2; K4DI90;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 E1;
DE            EC=6.3.2.19;
DE   AltName: Full=UbcH6;
DE   AltName: Full=Ubiquitin carrier protein E1;
DE   AltName: Full=Ubiquitin-protein ligase E1;
GN   Name=UBE2E1; Synonyms=UBCH6;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042296; F:ISG15 ligase activity; IDA:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.
DR   GO; GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:BHF-UCL.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UB2D4_HUMAN             Reviewed;         147 AA.
AC   Q9Y2X8; A4D1V0;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 D4;
DE            EC=6.3.2.19;
DE   AltName: Full=HBUCE1;
DE   AltName: Full=Ubiquitin carrier protein D4;
DE   AltName: Full=Ubiquitin-protein ligase D4;
GN   Name=UBE2D4; Synonyms=UBCH5D;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0035519; P:protein K29-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
//
ID   UB2E2_HUMAN             Reviewed;         201 AA.
AC   Q96LR5;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 E2;
DE            EC=6.3.2.19;
DE   AltName: Full=UbcH8;
DE   AltName: Full=Ubiquitin carrier protein E2;
DE   AltName: Full=Ubiquitin-protein ligase E2;
GN   Name=UBE2E2; Synonyms=UBCH8;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042296; F:ISG15 ligase activity; IDA:HGNC.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
//
ID   UB2E3_HUMAN             Reviewed;         207 AA.
AC   Q969T4; B2RAD6; D3DPG3; Q5U0R7; Q7Z4W4;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 E3;
DE            EC=6.3.2.19;
DE   AltName: Full=UbcH9;
DE   AltName: Full=Ubiquitin carrier protein E3;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-23 kDa;
DE   AltName: Full=Ubiquitin-protein ligase E3;
GN   Name=UBE2E3; Synonyms=UBCE4, UBCH9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   UB2G1_HUMAN             Reviewed;         170 AA.
AC   P62253; B2R7P2; D3DTK0; Q99462;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 G1;
DE            EC=6.3.2.19;
DE   AltName: Full=E217K;
DE   AltName: Full=UBC7;
DE   AltName: Full=Ubiquitin carrier protein G1;
DE   AltName: Full=Ubiquitin-protein ligase G1;
DE   Contains:
DE     RecName: Full=Ubiquitin-conjugating enzyme E2 G1, N-terminally processed;
GN   Name=UBE2G1; Synonyms=UBE2G;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UB2G2_HUMAN             Reviewed;         165 AA.
AC   P60604; A6NMQ7; A8K3L4; D3DSL7; P56554;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 G2;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein G2;
DE   AltName: Full=Ubiquitin-protein ligase G2;
GN   Name=UBE2G2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UB2J1_HUMAN             Reviewed;         318 AA.
AC   Q9Y385; A8K3F9; Q53F25; Q5W0N4; Q9BZ32; Q9NQL3; Q9NY66; Q9P011;
AC   Q9P0S0; Q9UF10;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 J1;
DE            EC=6.3.2.19;
DE   AltName: Full=Non-canonical ubiquitin-conjugating enzyme 1;
DE            Short=NCUBE-1;
DE   AltName: Full=Yeast ubiquitin-conjugating enzyme UBC6 homolog E;
DE            Short=HsUBC6e;
GN   Name=UBE2J1; Synonyms=NCUBE1; ORFNames=CGI-76, HSPC153, HSPC205;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; IMP:UniProtKB.
//
ID   UB2J2_HUMAN             Reviewed;         259 AA.
AC   Q8N2K1; A8MYC7; Q504T9; Q96N26; Q96T84;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 J2;
DE            EC=6.3.2.19;
DE   AltName: Full=Non-canonical ubiquitin-conjugating enzyme 2;
DE            Short=NCUBE-2;
GN   Name=UBE2J2; Synonyms=NCUBE2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   UB2L3_HUMAN             Reviewed;         154 AA.
AC   P68036; B2R4A7; B4DDG1; B4DSZ4; E7EWS7; P51966; P70653; Q9HAV1;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 L3;
DE            EC=6.3.2.19;
DE   AltName: Full=L-UBC;
DE   AltName: Full=UbcH7;
DE   AltName: Full=Ubiquitin carrier protein L3;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-F1;
DE   AltName: Full=Ubiquitin-protein ligase L3;
GN   Name=UBE2L3; Synonyms=UBCE7, UBCH7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; TAS:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:UniProtKB.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IDA:UniProtKB.
DR   GO; GO:0071383; P:cellular response to steroid hormone stimulus; IMP:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
//
ID   UB2L6_HUMAN             Reviewed;         153 AA.
AC   O14933; A6NDM6; A8MY53; Q8N5D8; Q9UEZ0;
DE   RecName: Full=Ubiquitin/ISG15-conjugating enzyme E2 L6;
DE            EC=6.3.2.19;
DE   AltName: Full=Retinoic acid-induced gene B protein;
DE            Short=RIG-B;
DE   AltName: Full=UbcH8;
DE   AltName: Full=Ubiquitin carrier protein L6;
DE   AltName: Full=Ubiquitin-protein ligase L6;
GN   Name=UBE2L6; Synonyms=UBCH8;
DR   GO; GO:0042296; F:ISG15 ligase activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032020; P:ISG15-protein conjugation; IEA:Ensembl.
DR   GO; GO:0019941; P:modification-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
//
ID   UB2Q1_HUMAN             Reviewed;         422 AA.
AC   Q7Z7E8; B4DF92; Q3B841; Q5I0X2; Q6IS04; Q6P7P2; Q96MV4; Q9BVX5;
AC   Q9UGL6;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 Q1;
DE            EC=6.3.2.19;
DE   AltName: Full=Protein NICE-5;
DE   AltName: Full=Ubiquitin carrier protein Q1;
DE   AltName: Full=Ubiquitin-protein ligase Q1;
GN   Name=UBE2Q1; Synonyms=NICE5, UBE2Q; ORFNames=PRO3094;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
//
ID   UB2Q2_HUMAN             Reviewed;         375 AA.
AC   Q8WVN8; B7Z3Q2; H3BRG2; Q8N4G6; Q96J08;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 Q2;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein Q2;
DE   AltName: Full=Ubiquitin-protein ligase Q2;
GN   Name=UBE2Q2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
//
ID   UB2R1_HUMAN             Reviewed;         236 AA.
AC   P49427; A8K689;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 R1;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-32 kDa complementing;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-CDC34;
DE   AltName: Full=Ubiquitin-protein ligase R1;
GN   Name=CDC34; Synonyms=UBCH3, UBE2R1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; NAS:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; NAS:UniProtKB.
DR   GO; GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0090261; P:positive regulation of inclusion body assembly; IEA:Ensembl.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070848; P:response to growth factor; IEA:Ensembl.
//
ID   UB2R2_HUMAN             Reviewed;         238 AA.
AC   Q712K3; D3DRL5; Q9NX64;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 R2;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein R2;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-CDC34B;
DE   AltName: Full=Ubiquitin-protein ligase R2;
GN   Name=UBE2R2; Synonyms=CDC34B, UBC3B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
//
ID   UB2V1_HUMAN             Reviewed;         147 AA.
AC   Q13404; E1P629; Q13403; Q13532; Q5TGE0; Q5TGE3; Q96H34; Q9GZT0;
AC   Q9GZW1; Q9H4J3; Q9H4J4; Q9UKL1; Q9UM48; Q9UM49; Q9UM50;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 variant 1;
DE            Short=UEV-1;
DE   AltName: Full=CROC-1;
DE   AltName: Full=TRAF6-regulated IKK activator 1 beta Uev1A;
GN   Name=UBE2V1; Synonyms=CROC1, UBE2V, UEV1; ORFNames=P/OKcl.19;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030154; P:cell differentiation; NAS:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:HGNC.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:HGNC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:ProtInc.
DR   GO; GO:0006282; P:regulation of DNA repair; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
//
ID   UB2V2_HUMAN             Reviewed;         145 AA.
AC   Q15819;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 variant 2;
DE   AltName: Full=DDVit 1;
DE   AltName: Full=Enterocyte differentiation-associated factor 1;
DE            Short=EDAF-1;
DE   AltName: Full=Enterocyte differentiation-promoting factor 1;
DE            Short=EDPF-1;
DE   AltName: Full=MMS2 homolog;
DE   AltName: Full=Vitamin D3-inducible protein;
GN   Name=UBE2V2; Synonyms=MMS2, UEV2;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0000729; P:DNA double-strand break processing; IMP:HGNC.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:ProtInc.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:HGNC.
DR   GO; GO:0006282; P:regulation of DNA repair; TAS:ProtInc.
//
ID   UBA1L_HUMAN             Reviewed;         381 AA.
AC   F5GYI3;
DE   RecName: Full=Ubiquitin-associated protein 1-like;
DE            Short=UBAP-1L;
GN   Name=UBAP1L;
//
ID   UBA1_HUMAN              Reviewed;        1058 AA.
AC   P22314; Q5JRR8; Q96E13;
DE   RecName: Full=Ubiquitin-like modifier-activating enzyme 1;
DE   AltName: Full=Protein A1S9;
DE   AltName: Full=Ubiquitin-activating enzyme E1;
GN   Name=UBA1; Synonyms=A1S9T, UBE1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   UBA3_HUMAN              Reviewed;         463 AA.
AC   Q8TBC4; A6NLB5; A8K027; O76088; Q9NTU3;
DE   RecName: Full=NEDD8-activating enzyme E1 catalytic subunit;
DE            EC=6.3.2.-;
DE   AltName: Full=NEDD8-activating enzyme E1C;
DE   AltName: Full=Ubiquitin-activating enzyme E1C;
DE   AltName: Full=Ubiquitin-like modifier-activating enzyme 3;
DE            Short=Ubiquitin-activating enzyme 3;
GN   Name=UBA3; Synonyms=UBE1C;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0007113; P:endomitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045116; P:protein neddylation; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
//
ID   UBA5_HUMAN              Reviewed;         404 AA.
AC   Q9GZZ9; A6NJL3; D3DNC8; Q96ST1;
DE   RecName: Full=Ubiquitin-like modifier-activating enzyme 5;
DE            Short=Ubiquitin-activating enzyme 5;
DE   AltName: Full=ThiFP1;
DE   AltName: Full=UFM1-activating enzyme;
DE   AltName: Full=Ubiquitin-activating enzyme E1 domain-containing protein 1;
GN   Name=UBA5; Synonyms=UBE1DC1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071566; F:UFM1 activating enzyme activity; IDA:UniProtKB.
DR   GO; GO:0071569; P:protein ufmylation; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:MGI.
//
ID   UBA6_HUMAN              Reviewed;        1052 AA.
AC   A0AVT1; A6N8M7; B2RAV3; Q4W5K0; Q6UV21; Q86T78; Q86TC7; Q8N5T3;
AC   Q8N9E4; Q9H3T7; Q9NVC9;
DE   RecName: Full=Ubiquitin-like modifier-activating enzyme 6;
DE            Short=Ubiquitin-activating enzyme 6;
DE   AltName: Full=Monocyte protein 4;
DE            Short=MOP-4;
DE   AltName: Full=Ubiquitin-activating enzyme E1-like protein 2;
DE            Short=E1-L2;
GN   Name=UBA6; Synonyms=MOP4, UBE1L2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019780; F:FAT10 activating enzyme activity; IMP:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   UBA7_HUMAN              Reviewed;        1012 AA.
AC   P41226; Q9BRB2;
DE   RecName: Full=Ubiquitin-like modifier-activating enzyme 7;
DE            Short=Ubiquitin-activating enzyme 7;
DE   AltName: Full=D8;
DE   AltName: Full=Ubiquitin-activating enzyme E1 homolog;
GN   Name=UBA7; Synonyms=UBE1L, UBE2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019782; F:ISG15 activating enzyme activity; IDA:HGNC.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:cellular protein modification process; IDA:HGNC.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.
DR   GO; GO:0019941; P:modification-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   UBAC1_HUMAN             Reviewed;         405 AA.
AC   Q9BSL1; O75500; Q9UMW7;
DE   RecName: Full=Ubiquitin-associated domain-containing protein 1;
DE            Short=UBA domain-containing protein 1;
DE   AltName: Full=E3 ubiquitin-protein ligase subunit KPC2;
DE   AltName: Full=Glialblastoma cell differentiation-related protein 1;
DE   AltName: Full=Kip1 ubiquitination-promoting complex protein 2;
GN   Name=UBAC1; Synonyms=GBDR1, KPC2, UBADC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   UBAC2_HUMAN             Reviewed;         344 AA.
AC   Q8NBM4; B3KNV7; Q0VAB5; Q5W0W6; Q5W0W9; Q6GQR2; Q6P4B0; Q8N2E8;
AC   Q96NW2;
DE   RecName: Full=Ubiquitin-associated domain-containing protein 2;
DE            Short=UBA domain-containing protein 2;
DE   AltName: Full=Phosphoglycerate dehydrogenase-like protein 1;
DE   Flags: Precursor;
GN   Name=UBAC2; Synonyms=PHGDHL1; ORFNames=PSEC0110;
DR   GO; GO:0070972; P:protein localization to endoplasmic reticulum; IDA:MGI.
//
ID   UBAD2_HUMAN             Reviewed;         164 AA.
AC   Q8IYN6;
DE   RecName: Full=UBA-like domain-containing protein 2;
GN   Name=UBALD2; Synonyms=FAM100B;
//
ID   UBAP1_HUMAN             Reviewed;         502 AA.
AC   Q9NZ09; B7Z348; B7Z8N9; D3DRL7; F5GXE2; F5H0J8; Q4V759; Q53FP7;
AC   Q5T7B3; Q6FI75; Q8NC52; Q8NCG6; Q8NCH9;
DE   RecName: Full=Ubiquitin-associated protein 1;
DE            Short=UBAP-1;
DE   AltName: Full=Nasopharyngeal carcinoma-associated gene 20 protein;
GN   Name=UBAP1; ORFNames=NAG20;
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:UniProtKB.
//
ID   UBAD1_HUMAN             Reviewed;         177 AA.
AC   Q8TB05; Q71MF6;
DE   RecName: Full=UBA-like domain-containing protein 1;
GN   Name=UBALD1; Synonyms=FAM100A; ORFNames=PP11303;
//
ID   UBAP2_HUMAN             Reviewed;        1119 AA.
AC   Q5T6F2; Q2M2R4; Q6PK34; Q8NC94; Q9P237;
DE   RecName: Full=Ubiquitin-associated protein 2;
DE            Short=UBAP-2;
GN   Name=UBAP2; Synonyms=KIAA1491;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   UBB_HUMAN               Reviewed;         229 AA.
AC   P0CG47; P02248; P02249; P02250; P62988; Q29120; Q6LBL4; Q6LDU5;
AC   Q8WYN8; Q91887; Q91888; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8;
AC   Q9UPK7;
DE   RecName: Full=Polyubiquitin-B;
DE   Contains:
DE     RecName: Full=Ubiquitin;
DE   Flags: Precursor;
GN   Name=UBB;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   UBC12_HUMAN             Reviewed;         183 AA.
AC   P61081; O76069; Q8VC50;
DE   RecName: Full=NEDD8-conjugating enzyme Ubc12;
DE            EC=6.3.2.-;
DE   AltName: Full=NEDD8 carrier protein;
DE   AltName: Full=NEDD8 protein ligase;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2 M;
GN   Name=UBE2M; Synonyms=UBC12;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0018169; F:ribosomal S6-glutamic acid ligase activity; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; IMP:UniProtKB.
DR   GO; GO:0043525; P:positive regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0045116; P:protein neddylation; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:GOC.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   UBC9_HUMAN              Reviewed;         158 AA.
AC   P63279; D3DU69; P50550; Q15698; Q59GX1; Q86VB3;
DE   RecName: Full=SUMO-conjugating enzyme UBC9;
DE            EC=6.3.2.-;
DE   AltName: Full=SUMO-protein ligase;
DE   AltName: Full=Ubiquitin carrier protein 9;
DE   AltName: Full=Ubiquitin carrier protein I;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2 I;
DE   AltName: Full=Ubiquitin-protein ligase I;
DE   AltName: Full=p18;
GN   Name=UBE2I; Synonyms=UBC9, UBCE9;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071535; F:RING-like zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0019789; F:SUMO ligase activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0033145; P:positive regulation of intracellular steroid hormone receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016925; P:protein sumoylation; IDA:BHF-UCL.
DR   GO; GO:0010469; P:regulation of receptor activity; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UBCP1_HUMAN             Reviewed;         318 AA.
AC   Q8WVY7; D3DQJ7; Q96DK5;
DE   RecName: Full=Ubiquitin-like domain-containing CTD phosphatase 1;
DE            EC=3.1.3.16;
DE   AltName: Full=Nuclear proteasome inhibitor UBLCP1;
GN   Name=UBLCP1;
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
//
ID   UBC_HUMAN               Reviewed;         685 AA.
AC   P0CG48; P02248; P02249; P02250; P62988; Q29120; Q6LBL4; Q6LDU5;
AC   Q8WYN8; Q91887; Q91888; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8;
AC   Q9UPK7;
DE   RecName: Full=Polyubiquitin-C;
DE   Contains:
DE     RecName: Full=Ubiquitin;
DE   Flags: Precursor;
GN   Name=UBC;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000187; P:activation of MAPK activity; TAS:Reactome.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.
DR   GO; GO:0042590; P:antigen processing and presentation of exogenous peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0007254; P:JNK cascade; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0002756; P:MyD88-independent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0007220; P:Notch receptor processing; TAS:Reactome.
DR   GO; GO:0007219; P:Notch signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; TAS:Reactome.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0032479; P:regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   UBD_HUMAN               Reviewed;         165 AA.
AC   O15205; B0UZT6; Q5STL2; Q5SUK2; Q96EC7;
DE   RecName: Full=Ubiquitin D;
DE   AltName: Full=Diubiquitin;
DE   AltName: Full=Ubiquitin-like protein FAT10;
GN   Name=UBD; Synonyms=FAT10;
DR   GO; GO:0070628; F:proteasome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070842; P:aggresome assembly; IDA:UniProtKB.
DR   GO; GO:0043011; P:myeloid dendritic cell differentiation; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032446; P:protein modification by small protein conjugation; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; NAS:UniProtKB.
DR   GO; GO:0034341; P:response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0010243; P:response to organonitrogen compound; IEA:Ensembl.
DR   GO; GO:0034612; P:response to tumor necrosis factor; IEP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   UBE2A_HUMAN             Reviewed;         152 AA.
AC   P49459; A6NFE9; A6NGR2; A6NMF5; B2R7R9; D3DWI1; Q4TTG1; Q96FX4;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 A;
DE            EC=6.3.2.19;
DE   AltName: Full=RAD6 homolog A;
DE            Short=HR6A;
DE            Short=hHR6A;
DE   AltName: Full=Ubiquitin carrier protein A;
DE   AltName: Full=Ubiquitin-protein ligase A;
GN   Name=UBE2A; Synonyms=RAD6A;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; IGI:UniProtKB.
DR   GO; GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0060135; P:maternal process involved in female pregnancy; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006301; P:postreplication repair; NAS:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; TAS:Reactome.
DR   GO; GO:0009411; P:response to UV; IGI:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
//
ID   UBE2B_HUMAN             Reviewed;         152 AA.
AC   P63146; B2R503; D3DQA2; P23567; Q4PJ15; Q9D0J6;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 B;
DE            EC=6.3.2.19;
DE   AltName: Full=RAD6 homolog B;
DE            Short=HR6B;
DE            Short=hHR6B;
DE   AltName: Full=Ubiquitin carrier protein B;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-17 kDa;
DE   AltName: Full=Ubiquitin-protein ligase B;
GN   Name=UBE2B; Synonyms=RAD6B;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0051026; P:chiasma assembly; IEA:Ensembl.
DR   GO; GO:0006281; P:DNA repair; IGI:UniProtKB.
DR   GO; GO:0033522; P:histone H2A ubiquitination; IMP:UniProtKB.
DR   GO; GO:0070076; P:histone lysine demethylation; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0006344; P:maintenance of chromatin silencing; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.
DR   GO; GO:0033128; P:negative regulation of histone phosphorylation; IEA:Ensembl.
DR   GO; GO:0010845; P:positive regulation of reciprocal meiotic recombination; IEA:Ensembl.
DR   GO; GO:0006301; P:postreplication repair; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IMP:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IDA:UniProtKB.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IGI:UniProtKB.
DR   GO; GO:0007288; P:sperm axoneme assembly; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:UniProtKB.
DR   GO; GO:0070193; P:synaptonemal complex organization; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   UBE2C_HUMAN             Reviewed;         179 AA.
AC   O00762; A6NP33; E1P5N7; G3XAB7;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 C;
DE            EC=6.3.2.19;
DE   AltName: Full=UbcH10;
DE   AltName: Full=Ubiquitin carrier protein C;
DE   AltName: Full=Ubiquitin-protein ligase C;
GN   Name=UBE2C; Synonyms=UBCH10;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0051488; P:activation of anaphase-promoting complex activity; TAS:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0008054; P:cyclin catabolic process; IDA:UniProtKB.
DR   GO; GO:0010458; P:exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0010994; P:free ubiquitin chain polymerization; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; TAS:Reactome.
DR   GO; GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0031536; P:positive regulation of exit from mitosis; IMP:UniProtKB.
DR   GO; GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007051; P:spindle organization; NAS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   UBE2F_HUMAN             Reviewed;         185 AA.
AC   Q969M7; A8K1Z8; B4DDT9; B4DFI1; B4DMK3; B4DZU2; B8ZZG2;
DE   RecName: Full=NEDD8-conjugating enzyme UBE2F;
DE            EC=6.3.2.-;
DE   AltName: Full=NEDD8 carrier protein UBE2F;
DE   AltName: Full=NEDD8 protein ligase UBE2F;
DE   AltName: Full=NEDD8-conjugating enzyme 2;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2 F;
GN   Name=UBE2F; Synonyms=NCE2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045116; P:protein neddylation; IDA:UniProtKB.
//
ID   UBE2H_HUMAN             Reviewed;         183 AA.
AC   P62256; A4D1L6; C9JY93; P37286; Q7Z6F4;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 H;
DE            EC=6.3.2.19;
DE   AltName: Full=UbcH2;
DE   AltName: Full=Ubiquitin carrier protein H;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-20K;
DE   AltName: Full=Ubiquitin-protein ligase H;
GN   Name=UBE2H;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UBE2K_HUMAN             Reviewed;         200 AA.
AC   P61086; A6NJC1; A8K5Y9; B2RDF8; C9JGP1; O54806; P27924; Q16721;
AC   Q9CVV9; Q9Y2D3;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 K;
DE            EC=6.3.2.19;
DE   AltName: Full=Huntingtin-interacting protein 2;
DE            Short=HIP-2;
DE   AltName: Full=Ubiquitin carrier protein;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-25 kDa;
DE            Short=Ubiquitin-conjugating enzyme E2(25K);
DE            Short=Ubiquitin-conjugating enzyme E2-25K;
DE   AltName: Full=Ubiquitin-protein ligase;
GN   Name=UBE2K; Synonyms=HIP2, LIG;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:UniProtKB.
DR   GO; GO:0070059; P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; IEA:Ensembl.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UBE2N_HUMAN             Reviewed;         152 AA.
AC   P61088; Q16781; Q53Y81;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 N;
DE            EC=6.3.2.19;
DE   AltName: Full=Bendless-like ubiquitin-conjugating enzyme;
DE   AltName: Full=Ubc13;
DE   AltName: Full=UbcH13;
DE   AltName: Full=Ubiquitin carrier protein N;
DE   AltName: Full=Ubiquitin-protein ligase N;
GN   Name=UBE2N; Synonyms=BLU;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:HGNC.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0000729; P:DNA double-strand break processing; IMP:HGNC.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:HGNC.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016574; P:histone ubiquitination; IMP:HGNC.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:HGNC.
DR   GO; GO:0031058; P:positive regulation of histone modification; IMP:HGNC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:HGNC.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:HGNC.
DR   GO; GO:0006301; P:postreplication repair; IMP:HGNC.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:HGNC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0006282; P:regulation of DNA repair; TAS:ProtInc.
DR   GO; GO:0033182; P:regulation of histone ubiquitination; IMP:HGNC.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034166; P:toll-like receptor 10 signaling pathway; TAS:Reactome.
DR   GO; GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.
DR   GO; GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
DR   GO; GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; TAS:Reactome.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038123; P:toll-like receptor TLR1:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0038124; P:toll-like receptor TLR6:TLR2 signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   UBE2O_HUMAN             Reviewed;        1292 AA.
AC   Q9C0C9; A6NDU5; Q69YP4; Q6PIZ2; Q86UA4; Q8N425; Q8TBN1; Q9BSW1;
AC   Q9H6E6; Q9H7E4; Q9H9B2;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 O;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein O;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2 of 230 kDa;
DE            Short=Ubiquitin-conjugating enzyme E2-230K;
DE   AltName: Full=Ubiquitin-protein ligase O;
GN   Name=UBE2O; Synonyms=KIAA1734;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
//
ID   UBE2S_HUMAN             Reviewed;         222 AA.
AC   Q16763; Q9BTC1;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 S;
DE            EC=6.3.2.19;
DE   AltName: Full=E2-EPF;
DE   AltName: Full=Ubiquitin carrier protein S;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-24 kDa;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2-EPF5;
DE   AltName: Full=Ubiquitin-protein ligase S;
GN   Name=UBE2S; Synonyms=E2EPF; ORFNames=OK/SW-cl.73;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0010458; P:exit from mitosis; IDA:UniProtKB.
DR   GO; GO:0010994; P:free ubiquitin chain polymerization; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0035519; P:protein K29-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
//
ID   UBE2T_HUMAN             Reviewed;         197 AA.
AC   Q9NPD8; Q2TU36;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 T;
DE            EC=6.3.2.19;
DE   AltName: Full=Cell proliferation-inducing gene 50 protein;
DE   AltName: Full=Ubiquitin carrier protein T;
DE   AltName: Full=Ubiquitin-protein ligase T;
GN   Name=UBE2T; ORFNames=HSPC150, PIG50;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0035519; P:protein K29-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
//
ID   UBE2U_HUMAN             Reviewed;         321 AA.
AC   Q5VVX9; Q8N1D4;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 U;
DE            EC=6.3.2.19;
DE   AltName: Full=Ubiquitin carrier protein U;
DE   AltName: Full=Ubiquitin-protein ligase U;
GN   Name=UBE2U;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
//
ID   UBE2W_HUMAN             Reviewed;         151 AA.
AC   Q96B02; B4DIV1; Q1XBE0; Q9H823; Q9HAG6; Q9NV07;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 W;
DE            EC=6.3.2.19;
DE   AltName: Full=N-terminus-conjugating E2;
DE   AltName: Full=Ubiquitin carrier protein W;
DE   AltName: Full=Ubiquitin-conjugating enzyme 16;
DE            Short=UBC-16;
DE   AltName: Full=Ubiquitin-protein ligase W;
GN   Name=UBE2W; Synonyms=UBC16;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0071218; P:cellular response to misfolded protein; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
//
ID   UBE2Z_HUMAN             Reviewed;         354 AA.
AC   Q9H832; A6N8M6; A6NC60; Q7L354; Q8TCM4; Q9H893;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 Z;
DE            EC=6.3.2.19;
DE   AltName: Full=Uba6-specific E2 conjugating enzyme 1;
DE            Short=Use1;
DE   AltName: Full=Ubiquitin carrier protein Z;
DE   AltName: Full=Ubiquitin-protein ligase Z;
GN   Name=UBE2Z; ORFNames=HOYS7;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
//
ID   UBE3A_HUMAN             Reviewed;         875 AA.
AC   Q05086; A8K8Z9; P78355; Q93066; Q9UEP4; Q9UEP5; Q9UEP6; Q9UEP7;
AC   Q9UEP8; Q9UEP9;
DE   RecName: Full=Ubiquitin-protein ligase E3A;
DE            EC=6.3.2.-;
DE   AltName: Full=E6AP ubiquitin-protein ligase;
DE   AltName: Full=Human papillomavirus E6-associated protein;
DE   AltName: Full=Oncogenic protein-associated protein E6-AP;
DE   AltName: Full=Renal carcinoma antigen NY-REN-54;
GN   Name=UBE3A; Synonyms=E6AP, EPVE6AP, HPVE6A;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0030521; P:androgen receptor signaling pathway; IBA:RefGenome.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060736; P:prostate gland growth; IEA:Ensembl.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0035037; P:sperm entry; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UBE3B_HUMAN             Reviewed;        1068 AA.
AC   Q7Z3V4; A5D8Z3; Q05BX9; Q659F7; Q7Z7Q1; Q9BXZ4;
DE   RecName: Full=Ubiquitin-protein ligase E3B;
DE            EC=6.3.2.-;
GN   Name=UBE3B;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   UBE3C_HUMAN             Reviewed;        1083 AA.
AC   Q15386; A4D235; A6NCP3; Q8TC15; Q96CR4; Q9UDU3;
DE   RecName: Full=Ubiquitin-protein ligase E3C;
DE            EC=6.3.2.-;
DE   AltName: Full=HectH2;
GN   Name=UBE3C; Synonyms=KIAA0010, KIAA10;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
//
ID   UBE3D_HUMAN             Reviewed;         389 AA.
AC   Q7Z6J8; B4DP63; Q5T4W2; Q6IPR4; Q75UG0; Q9NT42;
DE   RecName: Full=E3 ubiquitin-protein ligase E3D;
DE            EC=6.3.2.-;
DE   AltName: Full=UbcH10-binding protein with a HECT-like domain;
DE   AltName: Full=Ubiquitin-conjugating enzyme E2C-binding protein;
GN   Name=UBE3D; Synonyms=C6orf157, H10BH, UBE2CBP;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   UBE4A_HUMAN             Reviewed;        1066 AA.
AC   Q14139; B0YJB6; Q2M1H0; Q6P5T4; Q7Z639;
DE   RecName: Full=Ubiquitin conjugation factor E4 A;
GN   Name=UBE4A; Synonyms=KIAA0126;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UBE4B_HUMAN             Reviewed;        1302 AA.
AC   O95155; A8K8S9; G0ZJH6; O75169; O95338; Q5SZ12; Q5SZ16; Q96QD4;
AC   Q9BYI7;
DE   RecName: Full=Ubiquitin conjugation factor E4 B;
DE   AltName: Full=Homozygously deleted in neuroblastoma 1;
DE   AltName: Full=Ubiquitin fusion degradation protein 2;
GN   Name=UBE4B; Synonyms=HDNB1, KIAA0684, UFD2;
DR   GO; GO:0019899; F:enzyme binding; ISS:UniProtKB.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IEA:InterPro.
DR   GO; GO:0008626; P:granzyme-mediated apoptotic signaling pathway; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:MGI.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
//
ID   UBF1_HUMAN              Reviewed;         764 AA.
AC   P17480; A8K6R8;
DE   RecName: Full=Nucleolar transcription factor 1;
DE   AltName: Full=Autoantigen NOR-90;
DE   AltName: Full=Upstream-binding factor 1;
DE            Short=UBF-1;
GN   Name=UBTF; Synonyms=UBF, UBF1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000183; P:chromatin silencing at rDNA; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.
DR   GO; GO:0006356; P:regulation of transcription from RNA polymerase I promoter; TAS:ProtInc.
DR   GO; GO:0006363; P:termination of RNA polymerase I transcription; TAS:Reactome.
DR   GO; GO:0006362; P:transcription elongation from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006360; P:transcription from RNA polymerase I promoter; TAS:Reactome.
DR   GO; GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.
//
ID   UBFD1_HUMAN             Reviewed;         309 AA.
AC   O14562; A8MW58; D3DWF2;
DE   RecName: Full=Ubiquitin domain-containing protein UBFD1;
DE   AltName: Full=Ubiquitin-binding protein homolog;
GN   Name=UBFD1; Synonyms=UBPH;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   UBFL1_HUMAN             Reviewed;         393 AA.
AC   P0CB47; C9JMX8;
DE   RecName: Full=Putative upstream-binding factor 1-like protein 1;
GN   Name=UBTFL1; Synonyms=C11orf27;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   UBFL6_HUMAN             Reviewed;         400 AA.
AC   P0CB48;
DE   RecName: Full=Putative upstream-binding factor 1-like protein 6;
GN   Name=UBTFL6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
//
ID   UBIA1_HUMAN             Reviewed;         338 AA.
AC   Q9Y5Z9; B3KQG3; Q53GX3; Q5THD4;
DE   RecName: Full=UbiA prenyltransferase domain-containing protein 1;
DE            EC=2.5.1.-;
DE   AltName: Full=Transitional epithelial response protein 1;
GN   Name=UBIAD1; Synonyms=TERE1;
DR   GO; GO:0016209; F:antioxidant activity; IMP:UniProtKB.
DR   GO; GO:0004659; F:prenyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0009234; P:menaquinone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0042371; P:vitamin K biosynthetic process; IDA:UniProtKB.
//
ID   UBIML_HUMAN             Reviewed;         102 AA.
AC   A6NDN8;
DE   RecName: Full=Putative ubiquitin-like protein FUBI-like protein ENSP00000310146;
//
ID   UBIP1_HUMAN             Reviewed;         540 AA.
AC   Q9NZI7; Q68CT0; Q86Y57; Q9H8V0; Q9UD76; Q9UD78;
DE   RecName: Full=Upstream-binding protein 1;
DE   AltName: Full=Transcription factor LBP-1;
GN   Name=UBP1; Synonyms=LBP1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; TAS:ProtInc.
//
ID   UBIM_HUMAN              Reviewed;          74 AA.
AC   P35544; Q9H5V4;
DE   RecName: Full=Ubiquitin-like protein FUBI;
GN   Name=FAU;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   UBL3_HUMAN              Reviewed;         117 AA.
AC   O95164; B2R4J1; Q5RL72; Q5VZS0; Q6FIG8; Q96SG7;
DE   RecName: Full=Ubiquitin-like protein 3;
DE   AltName: Full=Membrane-anchored ubiquitin-fold protein;
DE            Short=HsMUB;
DE            Short=MUB;
DE   AltName: Full=Protein HCG-1;
DE   Flags: Precursor;
GN   Name=UBL3; Synonyms=PNSC1;
//
ID   UBL4A_HUMAN             Reviewed;         157 AA.
AC   P11441; Q5HY80;
DE   RecName: Full=Ubiquitin-like protein 4A;
DE   AltName: Full=Ubiquitin-like protein GDX;
GN   Name=UBL4A; Synonyms=DXS254E, GDX, UBL4;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019787; F:small conjugating protein ligase activity; TAS:ProtInc.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IMP:UniProtKB.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   UBL4B_HUMAN             Reviewed;         174 AA.
AC   Q8N7F7;
DE   RecName: Full=Ubiquitin-like protein 4B;
GN   Name=UBL4B;
//
ID   UBL5_HUMAN              Reviewed;          73 AA.
AC   Q9BZL1; Q2NL89;
DE   RecName: Full=Ubiquitin-like protein 5;
GN   Name=UBL5;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   UBL7_HUMAN              Reviewed;         380 AA.
AC   Q96S82; D3DW57; Q96I03;
DE   RecName: Full=Ubiquitin-like protein 7;
DE   AltName: Full=Bone marrow stromal cell ubiquitin-like protein;
DE            Short=BMSC-UbP;
DE   AltName: Full=Ubiquitin-like protein SB132;
GN   Name=UBL7; Synonyms=BMSCUBP; ORFNames=SB132;
//
ID   UBN1_HUMAN              Reviewed;        1134 AA.
AC   Q9NPG3; B7Z6D3; D3DUE8; Q13079; Q9P1P7;
DE   RecName: Full=Ubinuclein-1;
DE   AltName: Full=HIRA-binding protein;
DE   AltName: Full=Protein VT4;
DE   AltName: Full=Ubiquitously expressed nuclear protein;
GN   Name=UBN1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProt.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UBN2_HUMAN              Reviewed;        1347 AA.
AC   Q6ZU65; A4D1S2; Q2YDY4; Q6P1K0; Q86XN9; Q8N7D1;
DE   RecName: Full=Ubinuclein-2;
GN   Name=UBN2; Synonyms=KIAA2030;
//
ID   UBP10_HUMAN             Reviewed;         798 AA.
AC   Q14694; B2RDJ8; B4DS84; Q9BWG7; Q9NSL7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 10;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 10;
DE   AltName: Full=Ubiquitin thioesterase 10;
DE   AltName: Full=Ubiquitin-specific-processing protease 10;
GN   Name=USP10; Synonyms=KIAA0190;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; IDA:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP11_HUMAN             Reviewed;         963 AA.
AC   P51784; B2RTX1; Q8IUG6; Q9BWE1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 11;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 11;
DE   AltName: Full=Ubiquitin thioesterase 11;
DE   AltName: Full=Ubiquitin-specific-processing protease 11;
GN   Name=USP11; Synonyms=UHX1;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP12_HUMAN             Reviewed;         370 AA.
AC   O75317; A8K0X0; Q5VZV3; Q8TC49;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 12;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 12;
DE   AltName: Full=Ubiquitin thioesterase 12;
DE   AltName: Full=Ubiquitin-hydrolyzing enzyme 1;
DE   AltName: Full=Ubiquitin-specific-processing protease 12;
GN   Name=USP12; Synonyms=UBH1, USP12L1;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP13_HUMAN             Reviewed;         863 AA.
AC   Q92995; A8K2S3; B4DYF3; D3DNS2; Q96B25;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 13;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 13;
DE   AltName: Full=Isopeptidase T-3;
DE            Short=ISOT-3;
DE   AltName: Full=Ubiquitin thioesterase 13;
DE   AltName: Full=Ubiquitin-specific-processing protease 13;
GN   Name=USP13; Synonyms=ISOT3;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0030318; P:melanocyte differentiation; TAS:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP14_HUMAN             Reviewed;         494 AA.
AC   P54578; J3QRZ5; Q53XY5;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 14;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 14;
DE   AltName: Full=Ubiquitin thioesterase 14;
DE   AltName: Full=Ubiquitin-specific-processing protease 14;
GN   Name=USP14; Synonyms=TGT;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IMP:UniProtKB.
DR   GO; GO:0070628; F:proteasome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008193; F:tRNA guanylyltransferase activity; TAS:ProtInc.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IMP:GOC.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0050920; P:regulation of chemotaxis; IMP:UniProtKB.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP15_HUMAN             Reviewed;         981 AA.
AC   Q9Y4E8; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y5B5;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 15;
DE   AltName: Full=Ubiquitin thioesterase 15;
DE   AltName: Full=Ubiquitin-specific-processing protease 15;
DE   AltName: Full=Unph-2;
DE   AltName: Full=Unph4;
GN   Name=USP15; Synonyms=KIAA0529;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046332; F:SMAD binding; IPI:UniProtKB.
DR   GO; GO:0005160; F:transforming growth factor beta receptor binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035520; P:monoubiquitinated protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0060389; P:pathway-restricted SMAD protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP16_HUMAN             Reviewed;         823 AA.
AC   Q9Y5T5; A8MU43; B3KN13; B4DFV8; B4DY37; D3DSD9; Q53GP7; Q53HA0;
AC   Q5VKN8; Q8NEL3; Q9H3E6;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 16;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 16;
DE   AltName: Full=Ubiquitin thioesterase 16;
DE   AltName: Full=Ubiquitin-processing protease UBP-M;
DE   AltName: Full=Ubiquitin-specific-processing protease 16;
GN   Name=USP16; ORFNames=MSTP039;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070537; P:histone H2A K63-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IDA:UniProtKB.
DR   GO; GO:0035522; P:monoubiquitinated histone H2A deubiquitination; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0045901; P:positive regulation of translational elongation; IMP:UniProtKB.
DR   GO; GO:0051289; P:protein homotetramerization; IPI:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP19_HUMAN             Reviewed;        1318 AA.
AC   O94966; A5PKX8; A6H8U2; B4DGT3; B4DTZ0; E7EN22; E7ETS0; E9PEG8;
AC   Q3KQW4; Q641Q9; Q6NZY8; Q86XV9;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 19;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 19;
DE   AltName: Full=Ubiquitin thioesterase 19;
DE   AltName: Full=Ubiquitin-specific-processing protease 19;
DE   AltName: Full=Zinc finger MYND domain-containing protein 9;
GN   Name=USP19; Synonyms=KIAA0891, ZMYND9;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
DR   GO; GO:1900037; P:regulation of cellular response to hypoxia; IMP:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; ISS:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEP:UniProtKB.
DR   GO; GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
//
ID   UBP18_HUMAN             Reviewed;         372 AA.
AC   Q9UMW8; Q6IAD9; Q9NY71;
DE   RecName: Full=Ubl carboxyl-terminal hydrolase 18;
DE            EC=3.4.19.-;
DE   AltName: Full=43 kDa ISG15-specific protease;
DE            Short=hUBP43;
DE   AltName: Full=ISG15-specific-processing protease;
DE   AltName: Full=Ubl thioesterase 18;
GN   Name=USP18; Synonyms=ISG43;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP1_HUMAN              Reviewed;         785 AA.
AC   O94782; A0PJ95; D3DQ57; Q05BX7; Q59H66; Q9UFR0; Q9UNJ3;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 1;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 1;
DE            Short=hUBP;
DE   AltName: Full=Ubiquitin thioesterase 1;
DE   AltName: Full=Ubiquitin-specific-processing protease 1;
GN   Name=USP1;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0035520; P:monoubiquitinated protein deubiquitination; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006282; P:regulation of DNA repair; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP20_HUMAN             Reviewed;         914 AA.
AC   Q9Y2K6; Q541F1; Q8IXQ1; Q96LG5; Q9UQN8; Q9UQP0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 20;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 20;
DE   AltName: Full=Ubiquitin thioesterase 20;
DE   AltName: Full=Ubiquitin-specific-processing protease 20;
DE   AltName: Full=VHL-interacting deubiquitinating enzyme 2;
DE            Short=hVDU2;
GN   Name=USP20; Synonyms=KIAA1003, LSFR3A, VDU2;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP21_HUMAN             Reviewed;         565 AA.
AC   Q9UK80; Q59H60; Q5BKT5; Q5VTW9; Q5VTX0; Q9BTV1; Q9HBS2; Q9NYN4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 21;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 21;
DE   AltName: Full=Ubiquitin thioesterase 21;
DE   AltName: Full=Ubiquitin-specific-processing protease 21;
GN   Name=USP21; Synonyms=USP23; ORFNames=PP1490;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IMP:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0016578; P:histone deubiquitination; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP22_HUMAN             Reviewed;         525 AA.
AC   Q9UPT9; A0JNS3; Q2NLE2; Q6MZY4; Q8TBS8; Q96IW5;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 22;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 22;
DE   AltName: Full=Ubiquitin thioesterase 22;
DE   AltName: Full=Ubiquitin-specific-processing protease 22;
GN   Name=USP22; Synonyms=KIAA1063, USP3L;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0009790; P:embryo development; NAS:UniProtKB.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:GOC.
DR   GO; GO:0016574; P:histone ubiquitination; IDA:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP24_HUMAN             Reviewed;        2620 AA.
AC   Q9UPU5; Q6ZSY2; Q8N2Y4; Q9NXD1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 24;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 24;
DE   AltName: Full=Ubiquitin thioesterase 24;
DE   AltName: Full=Ubiquitin-specific-processing protease 24;
GN   Name=USP24; Synonyms=KIAA1057;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP26_HUMAN             Reviewed;         913 AA.
AC   Q9BXU7; B9WRT6; Q5H9H4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 26;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 26;
DE   AltName: Full=Ubiquitin thioesterase 26;
DE   AltName: Full=Ubiquitin-specific-processing protease 26;
GN   Name=USP26;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP25_HUMAN             Reviewed;        1055 AA.
AC   Q9UHP3; C0LSZ0; Q6DHZ9; Q9H9W1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 25;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 25;
DE   AltName: Full=USP on chromosome 21;
DE   AltName: Full=Ubiquitin thioesterase 25;
DE   AltName: Full=Ubiquitin-specific-processing protease 25;
GN   Name=USP25; Synonyms=USP21;
DR   GO; GO:0008233; F:peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032183; F:SUMO binding; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP27_HUMAN             Reviewed;         438 AA.
AC   A6NNY8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 27;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 27;
DE   AltName: Full=Ubiquitin carboxyl-terminal hydrolase 22-like;
DE   AltName: Full=Ubiquitin thioesterase 27;
DE   AltName: Full=Ubiquitin-specific-processing protease 27;
DE   AltName: Full=X-linked ubiquitin carboxyl-terminal hydrolase 27;
GN   Name=USP27X; Synonyms=USP22L, USP27;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP28_HUMAN             Reviewed;        1077 AA.
AC   Q96RU2; B0YJC0; B0YJC1; Q9P213;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 28;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 28;
DE   AltName: Full=Ubiquitin thioesterase 28;
DE   AltName: Full=Ubiquitin-specific-processing protease 28;
GN   Name=USP28; Synonyms=KIAA1515;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; IDA:UniProtKB.
DR   GO; GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP2L_HUMAN             Reviewed;        1087 AA.
AC   Q14157; B4E0U8; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4;
AC   Q9UGL5;
DE   RecName: Full=Ubiquitin-associated protein 2-like;
DE   AltName: Full=Protein NICE-4;
GN   Name=UBAP2L; Synonyms=KIAA0144, NICE4;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IMP:UniProtKB.
//
ID   UBP29_HUMAN             Reviewed;         922 AA.
AC   Q9HBJ7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 29;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 29;
DE   AltName: Full=Ubiquitin thioesterase 29;
DE   AltName: Full=Ubiquitin-specific-processing protease 29;
GN   Name=USP29;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP2_HUMAN              Reviewed;         605 AA.
AC   O75604; B0YJB8; E9PPM2; Q8IUM2; Q8IW04; Q96MB9; Q9BQ21;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 2;
DE            EC=3.4.19.12;
DE   AltName: Full=41 kDa ubiquitin-specific protease;
DE   AltName: Full=Deubiquitinating enzyme 2;
DE   AltName: Full=Ubiquitin thioesterase 2;
DE   AltName: Full=Ubiquitin-specific-processing protease 2;
GN   Name=USP2; Synonyms=UBP41;
DR   GO; GO:0030332; F:cyclin binding; IPI:UniProtKB.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0048643; P:positive regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP30_HUMAN             Reviewed;         517 AA.
AC   Q70CQ3; Q8WTU7; Q96JX4; Q9BSS3;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 30;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 30;
DE   AltName: Full=Ubiquitin thioesterase 30;
DE   AltName: Full=Ubiquitin-specific-processing protease 30;
DE            Short=Ub-specific protease 30;
GN   Name=USP30;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP31_HUMAN             Reviewed;        1352 AA.
AC   Q70CQ4; Q6AW97; Q6ZTC0; Q6ZTN2; Q9ULL7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 31;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 31;
DE   AltName: Full=Ubiquitin thioesterase 31;
DE   AltName: Full=Ubiquitin-specific-processing protease 31;
GN   Name=USP31; Synonyms=KIAA1203;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP32_HUMAN             Reviewed;        1604 AA.
AC   Q8NFA0; Q9BX85; Q9Y591;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 32;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 32;
DE   AltName: Full=Renal carcinoma antigen NY-REN-60;
DE   AltName: Full=Ubiquitin thioesterase 32;
DE   AltName: Full=Ubiquitin-specific-processing protease 32;
DE   Flags: Precursor;
GN   Name=USP32; Synonyms=USP10;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IEA:InterPro.
DR   GO; GO:0016579; P:protein deubiquitination; TAS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP33_HUMAN             Reviewed;         942 AA.
AC   Q8TEY7; Q8TEY6; Q96AV6; Q9H9F0; Q9UPQ5;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 33;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 33;
DE   AltName: Full=Ubiquitin thioesterase 33;
DE   AltName: Full=Ubiquitin-specific-processing protease 33;
DE   AltName: Full=VHL-interacting deubiquitinating enzyme 1;
DE            Short=hVDU1;
GN   Name=USP33; Synonyms=KIAA1097, VDU1;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0001664; F:G-protein coupled receptor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0016477; P:cell migration; ISS:UniProtKB.
DR   GO; GO:0051298; P:centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB.
//
ID   UBP34_HUMAN             Reviewed;        3546 AA.
AC   Q70CQ2; A8MWD0; B3KWU9; O60316; O94834; Q3B777; Q6P6C9; Q7L8P6;
AC   Q8N3T9; Q8TBW2; Q9UGA1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 34;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 34;
DE   AltName: Full=Ubiquitin thioesterase 34;
DE   AltName: Full=Ubiquitin-specific-processing protease 34;
GN   Name=USP34; Synonyms=KIAA0570, KIAA0729;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   UBP35_HUMAN             Reviewed;        1018 AA.
AC   Q9P2H5;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 35;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 35;
DE   AltName: Full=Ubiquitin thioesterase 35;
DE   AltName: Full=Ubiquitin-specific-processing protease 35;
GN   Name=USP35; Synonyms=KIAA1372, USP34;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP36_HUMAN             Reviewed;        1121 AA.
AC   Q9P275; Q05C98; Q05DD0; Q6IQ38; Q8NDM8; Q9NVC8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 36;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 36;
DE   AltName: Full=Ubiquitin thioesterase 36;
DE   AltName: Full=Ubiquitin-specific-processing protease 36;
GN   Name=USP36; Synonyms=KIAA1453;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP37_HUMAN             Reviewed;         979 AA.
AC   Q86T82; A2RUQ8; B7ZM38; B7ZM41; E9PHL3; Q2KHT2; Q53S10; Q7Z3A5;
AC   Q9HCH8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 37;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 37;
DE   AltName: Full=Ubiquitin thioesterase 37;
DE   AltName: Full=Ubiquitin-specific-processing protease 37;
GN   Name=USP37; Synonyms=KIAA1594;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP3_HUMAN              Reviewed;         520 AA.
AC   Q9Y6I4; B4DVU5; F5H1A6; Q8WVD0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 3;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 3;
DE   AltName: Full=Ubiquitin thioesterase 3;
DE   AltName: Full=Ubiquitin-specific-processing protease 3;
GN   Name=USP3;
DR   GO; GO:0042393; F:histone binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0016578; P:histone deubiquitination; IDA:UniProtKB.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP40_HUMAN             Reviewed;        1235 AA.
AC   Q9NVE5; Q6NX38; Q70EL0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 40;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 40;
DE   AltName: Full=Ubiquitin thioesterase 40;
DE   AltName: Full=Ubiquitin-specific-processing protease 40;
GN   Name=USP40;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP42_HUMAN             Reviewed;        1324 AA.
AC   Q9H9J4; A2RUE3; B5MDA5; Q0VIN8; Q3C166; Q6P9B4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 42;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 42;
DE   AltName: Full=Ubiquitin thioesterase 42;
DE   AltName: Full=Ubiquitin-specific-processing protease 42;
GN   Name=USP42;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP41_HUMAN             Reviewed;         358 AA.
AC   Q3LFD5; A8MXD0; Q70BM7;
DE   RecName: Full=Putative ubiquitin carboxyl-terminal hydrolase 41;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 41;
DE   AltName: Full=Ubiquitin thioesterase 41;
DE   AltName: Full=Ubiquitin-specific-processing protease 41;
GN   Name=USP41;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP38_HUMAN             Reviewed;        1042 AA.
AC   Q8NB14; B3KX93; Q3ZCV1; Q8NDF5; Q96DK6; Q96PZ6; Q9BY55;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 38;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 38;
DE   AltName: Full=HP43.8KD;
DE   AltName: Full=Ubiquitin thioesterase 38;
DE   AltName: Full=Ubiquitin-specific-processing protease 38;
GN   Name=USP38; Synonyms=KIAA1891;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP43_HUMAN             Reviewed;        1123 AA.
AC   Q70EL4; A6NDT9; B7ZLT9; B7ZVX5; Q8N2C5; Q96DQ6;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 43;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 43;
DE   AltName: Full=Ubiquitin thioesterase 43;
DE   AltName: Full=Ubiquitin-specific-processing protease 43;
GN   Name=USP43;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP44_HUMAN             Reviewed;         712 AA.
AC   Q9H0E7; B2RDW3;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 44;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 44;
DE   AltName: Full=Ubiquitin thioesterase 44;
DE   AltName: Full=Ubiquitin-specific-processing protease 44;
GN   Name=USP44;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0051322; P:anaphase; IMP:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0060564; P:negative regulation of mitotic anaphase-promoting complex activity; IMP:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0090266; P:regulation of mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.
DR   GO; GO:0090231; P:regulation of spindle checkpoint; IMP:UniProtKB.
//
ID   UBP45_HUMAN             Reviewed;         814 AA.
AC   Q70EL2; B2RXG0; Q5T062; Q86T44; Q86TC0; Q9BRU1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 45;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 45;
DE   AltName: Full=Ubiquitin thioesterase 45;
DE   AltName: Full=Ubiquitin-specific-processing protease 45;
GN   Name=USP45;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP47_HUMAN             Reviewed;        1375 AA.
AC   Q96K76; B3KXF5; Q658U0; Q86Y73; Q8TEP6; Q9BWI0; Q9NWN1;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 47;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 47;
DE   AltName: Full=Ubiquitin thioesterase 47;
DE   AltName: Full=Ubiquitin-specific-processing protease 47;
GN   Name=USP47;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0071987; F:WD40-repeat domain binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0034644; P:cellular response to UV; ISS:UniProtKB.
DR   GO; GO:0035520; P:monoubiquitinated protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.
DR   GO; GO:0010972; P:negative regulation of G2/M transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:1902230; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP46_HUMAN             Reviewed;         366 AA.
AC   P62068; B7Z3Y7; B7Z675; B7Z7S3; G8ACC7; Q80V95; Q9H7U4; Q9H9T8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 46;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 46;
DE   AltName: Full=Ubiquitin thioesterase 46;
DE   AltName: Full=Ubiquitin-specific-processing protease 46;
GN   Name=USP46;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; ISS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP48_HUMAN             Reviewed;        1035 AA.
AC   Q86UV5; B7ZKS7; Q2M3I4; Q5SZI4; Q5T3T5; Q6NX53; Q8N3F6; Q96F64;
AC   Q96IQ3; Q9H5N3; Q9H5T7; Q9NUJ6; Q9NXR0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 48;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 48;
DE   AltName: Full=Ubiquitin thioesterase 48;
DE   AltName: Full=Ubiquitin-specific-processing protease 48;
GN   Name=USP48; Synonyms=USP31;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP49_HUMAN             Reviewed;         688 AA.
AC   Q70CQ1; Q5T3D9; Q5T3E0; Q96CK4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 49;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 49;
DE   AltName: Full=Ubiquitin thioesterase 49;
DE   AltName: Full=Ubiquitin-specific-processing protease 49;
GN   Name=USP49;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0035616; P:histone H2B conserved C-terminal lysine deubiquitination; IDA:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP4_HUMAN              Reviewed;         963 AA.
AC   Q13107; A8K6Y0; C9IY91; O43452; O43453; Q08AK8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 4;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 4;
DE   AltName: Full=Ubiquitin thioesterase 4;
DE   AltName: Full=Ubiquitin-specific-processing protease 4;
DE   AltName: Full=Ubiquitous nuclear protein homolog;
GN   Name=USP4; Synonyms=UNP, UNPH;
DR   GO; GO:0031685; F:adenosine receptor binding; IPI:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0034394; P:protein localization to cell surface; IDA:UniProtKB.
DR   GO; GO:0031647; P:regulation of protein stability; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP50_HUMAN             Reviewed;         339 AA.
AC   Q70EL3; E9PP86;
DE   RecName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 50;
DE   AltName: Full=Inactive ubiquitin-specific peptidase 50;
GN   Name=USP50;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP53_HUMAN             Reviewed;        1073 AA.
AC   Q70EK8; Q68DA5; Q8WVQ5; Q9P2J7;
DE   RecName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 53;
DE   AltName: Full=Inactive ubiquitin-specific peptidase 53;
GN   Name=USP53; Synonyms=KIAA1350;
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP54_HUMAN             Reviewed;        1684 AA.
AC   Q70EL1; A1L4Q4; A3KFK3; A3KFK5; A3KFK6; A3KFK7; A6PVS4; A6PVS5;
AC   A6PVS6; A6PVS7; B3KVY1; B9ZVM1; Q5F2F4; Q6P1N6; Q6ZSP1; Q6ZSR1;
AC   Q6ZTM0; Q8N1X2;
DE   RecName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 54;
DE   AltName: Full=Inactive ubiquitin-specific peptidase 54;
GN   Name=USP54; Synonyms=C10orf29;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP51_HUMAN             Reviewed;         711 AA.
AC   Q70EK9; Q8IWJ8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 51;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 51;
DE   AltName: Full=Ubiquitin thioesterase 51;
DE   AltName: Full=Ubiquitin-specific-processing protease 51;
GN   Name=USP51;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:FlyBase.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:FlyBase.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP5_HUMAN              Reviewed;         858 AA.
AC   P45974; D3DUS7; D3DUS8; Q96J22;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 5;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 5;
DE   AltName: Full=Isopeptidase T;
DE   AltName: Full=Ubiquitin thioesterase 5;
DE   AltName: Full=Ubiquitin-specific-processing protease 5;
GN   Name=USP5; Synonyms=ISOT;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP6_HUMAN              Reviewed;        1406 AA.
AC   P35125; Q15634; Q86WP6; Q8IWT4;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 6;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 6;
DE   AltName: Full=Proto-oncogene TRE-2;
DE   AltName: Full=Ubiquitin thioesterase 6;
DE   AltName: Full=Ubiquitin-specific-processing protease 6;
GN   Name=USP6; Synonyms=HRP1, TRE2;
DR   GO; GO:0005516; F:calmodulin binding; IPI:UniProtKB.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:UniProtKB.
DR   GO; GO:0003676; F:nucleic acid binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; NAS:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0060627; P:regulation of vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBP7_HUMAN              Reviewed;        1102 AA.
AC   Q93009; A6NMY8; B7Z815; H0Y3G8;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 7;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 7;
DE   AltName: Full=Herpesvirus-associated ubiquitin-specific protease;
DE   AltName: Full=Ubiquitin thioesterase 7;
DE   AltName: Full=Ubiquitin-specific-processing protease 7;
GN   Name=USP7; Synonyms=HAUSP;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IMP:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0010216; P:maintenance of DNA methylation; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UBP8_HUMAN              Reviewed;        1118 AA.
AC   P40818; B4DKA8; Q2TB31; Q7Z3U2; Q86VA0; Q8IWI7;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 8;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme 8;
DE   AltName: Full=Ubiquitin isopeptidase Y;
DE            Short=hUBPy;
DE   AltName: Full=Ubiquitin thioesterase 8;
DE   AltName: Full=Ubiquitin-specific-processing protease 8;
GN   Name=USP8; Synonyms=KIAA0055, UBPY;
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0007032; P:endosome organization; IMP:UniProtKB.
DR   GO; GO:0000281; P:mitotic cytokinesis; IMP:MGI.
DR   GO; GO:0016579; P:protein deubiquitination; IMP:MGI.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UBQL1_HUMAN             Reviewed;         589 AA.
AC   Q9UMX0; Q5T6J5; Q5T6J9; Q8IXS9; Q8N2Q3; Q9H0T8; Q9H3R4; Q9HAZ5;
DE   RecName: Full=Ubiquilin-1;
DE   AltName: Full=Protein linking IAP with cytoskeleton 1;
DE            Short=PLIC-1;
DE            Short=hPLIC-1;
GN   Name=UBQLN1; Synonyms=DA41, PLIC1;
DR   GO; GO:0019900; F:kinase binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071456; P:cellular response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:1902175; P:regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; IMP:BHF-UCL.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IDA:HGNC.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IMP:BHF-UCL.
//
ID   UBQL3_HUMAN             Reviewed;         655 AA.
AC   Q9H347; Q9NRE0;
DE   RecName: Full=Ubiquilin-3;
GN   Name=UBQLN3;
//
ID   UBQL2_HUMAN             Reviewed;         624 AA.
AC   Q9UHD9; O94798; Q5D027; Q9H3W6; Q9HAZ4;
DE   RecName: Full=Ubiquilin-2;
DE   AltName: Full=Chap1;
DE   AltName: Full=DSK2 homolog;
DE   AltName: Full=Protein linking IAP with cytoskeleton 2;
DE            Short=PLIC-2;
DE            Short=hPLIC-2;
DE   AltName: Full=Ubiquitin-like product Chap1/Dsk2;
GN   Name=UBQLN2; Synonyms=N4BP4, PLIC2; ORFNames=HRIHFB2157;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   UBQL4_HUMAN             Reviewed;         601 AA.
AC   Q9NRR5; A6ND44; B2RAY7; Q5VYA0; Q5VYA1; Q9BR98; Q9UHX4;
DE   RecName: Full=Ubiquilin-4;
DE   AltName: Full=Ataxin-1 interacting ubiquitin-like protein;
DE            Short=A1Up;
DE   AltName: Full=Ataxin-1 ubiquitin-like-interacting protein A1U;
DE   AltName: Full=Connexin43-interacting protein of 75 kDa;
DE            Short=CIP75;
GN   Name=UBQLN4; Synonyms=C1orf6, CIP75, UBIN;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
//
ID   UBQLN_HUMAN             Reviewed;         475 AA.
AC   Q8IYU4; Q6ZRU1; Q96EK3; Q96MB0;
DE   RecName: Full=Ubiquilin-like protein;
GN   Name=UBQLNL;
//
ID   UBR1_HUMAN              Reviewed;        1749 AA.
AC   Q8IWV7; O60708; O75492; Q14D45; Q68DN9; Q8IWY6; Q96JY4;
DE   RecName: Full=E3 ubiquitin-protein ligase UBR1;
DE            EC=6.3.2.-;
DE   AltName: Full=N-recognin-1;
DE   AltName: Full=Ubiquitin-protein ligase E3-alpha-1;
DE   AltName: Full=Ubiquitin-protein ligase E3-alpha-I;
GN   Name=UBR1;
DR   GO; GO:0070728; F:leucine binding; IDA:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071233; P:cellular response to leucine; IDA:UniProtKB.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   UBR2_HUMAN              Reviewed;        1755 AA.
AC   Q8IWV8; O15057; Q4VXK2; Q5TFH6; Q6P2I2; Q6ZUD0;
DE   RecName: Full=E3 ubiquitin-protein ligase UBR2;
DE            EC=6.3.2.-;
DE   AltName: Full=N-recognin-2;
DE   AltName: Full=Ubiquitin-protein ligase E3-alpha-2;
DE   AltName: Full=Ubiquitin-protein ligase E3-alpha-II;
GN   Name=UBR2; Synonyms=C6orf133, KIAA0349;
DR   GO; GO:0070728; F:leucine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0071233; P:cellular response to leucine; IDA:UniProtKB.
DR   GO; GO:0006342; P:chromatin silencing; ISS:UniProtKB.
DR   GO; GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.
DR   GO; GO:0007141; P:male meiosis I; IEA:Ensembl.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IMP:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   UBR3_HUMAN              Reviewed;        1888 AA.
AC   Q6ZT12; B4DZR7; Q2KHN5; Q6ZR55; Q6ZSC2; Q8IVE7; Q8ND96;
DE   RecName: Full=E3 ubiquitin-protein ligase UBR3;
DE            EC=6.3.2.-;
DE   AltName: Full=N-recognin-3;
DE   AltName: Full=Ubiquitin-protein ligase E3-alpha-3;
DE   AltName: Full=Ubiquitin-protein ligase E3-alpha-III;
DE   AltName: Full=Zinc finger protein 650;
GN   Name=UBR3; Synonyms=KIAA2024, ZNF650;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0009790; P:embryo development; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042048; P:olfactory behavior; IEA:Ensembl.
DR   GO; GO:0007608; P:sensory perception of smell; ISS:UniProtKB.
DR   GO; GO:0001967; P:suckling behavior; ISS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
//
ID   UBR4_HUMAN              Reviewed;        5183 AA.
AC   Q5T4S7; A8MPT2; A8MQ33; A8MQB1; O60646; O75050; Q4QRK5; Q5T4S8;
AC   Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5;
AC   Q8WV67; Q9HA46; Q9P2N9; Q9UG82;
DE   RecName: Full=E3 ubiquitin-protein ligase UBR4;
DE            EC=6.3.2.-;
DE   AltName: Full=600 kDa retinoblastoma protein-associated factor;
DE   AltName: Full=N-recognin-4;
DE   AltName: Full=Retinoblastoma-associated factor of 600 kDa;
DE            Short=RBAF600;
DE            Short=p600;
DE   AltName: Full=Zinc finger UBR1-type protein 1;
GN   Name=UBR4; Synonyms=KIAA0462, KIAA1307, RBAF600, ZUBR1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UBR5_HUMAN              Reviewed;        2799 AA.
AC   O95071; B2RP24; J3KMW7; O94970; Q9NPL3;
DE   RecName: Full=E3 ubiquitin-protein ligase UBR5;
DE            EC=6.3.2.-;
DE   AltName: Full=E3 ubiquitin-protein ligase, HECT domain-containing 1;
DE   AltName: Full=Hyperplastic discs protein homolog;
DE            Short=hHYD;
DE   AltName: Full=Progestin-induced protein;
GN   Name=UBR5; Synonyms=EDD, EDD1, HYD, KIAA0896;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:2000780; P:negative regulation of double-strand break repair; IMP:UniProtKB.
DR   GO; GO:1901315; P:negative regulation of histone H2A K63-linked ubiquitination; IMP:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:BHF-UCL.
DR   GO; GO:0050847; P:progesterone receptor signaling pathway; IDA:HGNC.
DR   GO; GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UBR7_HUMAN              Reviewed;         425 AA.
AC   Q8N806; Q86U21; Q86UA9; Q96BY0; Q9NVV6;
DE   RecName: Full=Putative E3 ubiquitin-protein ligase UBR7;
DE            EC=6.3.2.-;
DE   AltName: Full=N-recognin-7;
GN   Name=UBR7; Synonyms=C14orf130;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   UBS3A_HUMAN             Reviewed;         661 AA.
AC   P57075; G5E9E4; Q6HA34; Q6HA35; Q6ISI6; Q6ISK3; Q6ISS9;
DE   RecName: Full=Ubiquitin-associated and SH3 domain-containing protein A;
DE   AltName: Full=Cbl-interacting protein 4;
DE            Short=CLIP4;
DE   AltName: Full=Suppressor of T-cell receptor signaling 2;
DE            Short=STS-2;
DE   AltName: Full=T-cell ubiquitin ligand 1;
DE            Short=TULA-1;
GN   Name=UBASH3A; Synonyms=STS2;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0050860; P:negative regulation of T cell receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0001817; P:regulation of cytokine production; IEA:Ensembl.
//
ID   UBS3B_HUMAN             Reviewed;         649 AA.
AC   Q8TF42; Q53GT5; Q53GT8; Q8NBV7; Q96IG9; Q96NZ2;
DE   RecName: Full=Ubiquitin-associated and SH3 domain-containing protein B;
DE            EC=3.1.3.48;
DE   AltName: Full=Cbl-interacting protein p70;
DE   AltName: Full=Suppressor of T-cell receptor signaling 1;
DE            Short=STS-1;
DE   AltName: Full=T-cell ubiquitin ligand 2;
DE            Short=TULA-2;
DE   AltName: Full=Tyrosine-protein phosphatase STS1/TULA2;
GN   Name=UBASH3B; Synonyms=KIAA1959, STS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0090331; P:negative regulation of platelet aggregation; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IEA:Ensembl.
//
ID   UBTD1_HUMAN             Reviewed;         227 AA.
AC   Q9HAC8; D3DR57; Q53HI3;
DE   RecName: Full=Ubiquitin domain-containing protein 1;
GN   Name=UBTD1;
//
ID   UBTD2_HUMAN             Reviewed;         234 AA.
AC   Q8WUN7; Q8TDQ3;
DE   RecName: Full=Ubiquitin domain-containing protein 2;
DE   AltName: Full=Dendritic cell-derived ubiquitin-like protein;
DE            Short=DC-UbP;
DE   AltName: Full=Ubiquitin-like protein SB72;
GN   Name=UBTD2; Synonyms=DCUBP; ORFNames=SB72;
//
ID   UBX10_HUMAN             Reviewed;         280 AA.
AC   Q96LJ8; Q5R386;
DE   RecName: Full=UBX domain-containing protein 10;
DE   AltName: Full=UBX domain-containing protein 3;
GN   Name=UBXN10; Synonyms=UBXD3;
//
ID   UBX11_HUMAN             Reviewed;         520 AA.
AC   Q5T124; D3DPK6; Q5T117; Q5T120; Q5T125; Q5T126; Q5T129; Q5T131;
AC   Q5T133; Q63HM6; Q71RB3; Q8IY27; Q8N1L6; Q8N9M4; Q8NA18; Q8NFE3;
AC   Q8NFE4; Q8NFE6;
DE   RecName: Full=UBX domain-containing protein 11;
DE   AltName: Full=Colorectal tumor-associated antigen COA-1;
DE   AltName: Full=Socius;
DE   AltName: Full=UBX domain-containing protein 5;
GN   Name=UBXN11; Synonyms=SOC, UBXD5; ORFNames=PP2243;
//
ID   UBX2A_HUMAN             Reviewed;         259 AA.
AC   P68543; A8K577; Q569G8;
DE   RecName: Full=UBX domain-containing protein 2A;
DE   AltName: Full=UBX domain-containing protein 4;
GN   Name=UBXN2A; Synonyms=UBXD4;
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0031396; P:regulation of protein ubiquitination; IEA:Ensembl.
//
ID   UBX2B_HUMAN             Reviewed;         331 AA.
AC   Q14CS0; B3KWZ3;
DE   RecName: Full=UBX domain-containing protein 2B;
DE   AltName: Full=NSFL1 cofactor p37;
DE   AltName: Full=p97 cofactor p37;
GN   Name=UBXN2B;
//
ID   UBXN1_HUMAN             Reviewed;         297 AA.
AC   Q04323; Q9BV93; Q9BVV5;
DE   RecName: Full=UBX domain-containing protein 1;
DE   AltName: Full=SAPK substrate protein 1;
DE   AltName: Full=UBA/UBX 33.3 kDa protein;
GN   Name=UBXN1; Synonyms=SAKS1;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0071796; F:K6-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
//
ID   UBXN4_HUMAN             Reviewed;         508 AA.
AC   Q92575; A8K9W4; Q4ZG56; Q8IYM5;
DE   RecName: Full=UBX domain-containing protein 4;
DE   AltName: Full=Erasin;
DE   AltName: Full=UBX domain-containing protein 2;
GN   Name=UBXN4; Synonyms=KIAA0242, UBXD2, UBXDC1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW.
//
ID   UBXN6_HUMAN             Reviewed;         441 AA.
AC   Q9BZV1; D6W626; Q96AH1; Q96IK9; Q9BZV0;
DE   RecName: Full=UBX domain-containing protein 6;
DE   AltName: Full=UBX domain-containing protein 1;
GN   Name=UBXN6; Synonyms=UBXD1, UBXDC2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   UBXN7_HUMAN             Reviewed;         489 AA.
AC   O94888; D3DXB3; Q6ZP77; Q86X20; Q8N327;
DE   RecName: Full=UBX domain-containing protein 7;
GN   Name=UBXN7; Synonyms=KIAA0794, UBXD7;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IDA:BHF-UCL.
//
ID   UBXN8_HUMAN             Reviewed;         270 AA.
AC   O00124; Q7Z6F2;
DE   RecName: Full=UBX domain-containing protein 8;
DE   AltName: Full=Reproduction 8 protein;
DE            Short=Rep-8 protein;
DE   AltName: Full=UBX domain-containing protein 6;
GN   Name=UBXN8; Synonyms=D8S2298E, REP8, UBXD6;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   UCHL1_HUMAN             Reviewed;         223 AA.
AC   P09936; Q4W5K6; Q71UM0;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L1;
DE            Short=UCH-L1;
DE            EC=3.4.19.12;
DE            EC=6.-.-.-;
DE   AltName: Full=Neuron cytoplasmic protein 9.5;
DE   AltName: Full=PGP 9.5;
DE            Short=PGP9.5;
DE   AltName: Full=Ubiquitin thioesterase L1;
DE   Flags: Precursor;
GN   Name=UCHL1;
DR   GO; GO:0031694; F:alpha-2A adrenergic receptor binding; IPI:BHF-UCL.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008242; F:omega peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IEA:InterPro.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007412; P:axon target recognition; IEA:Ensembl.
DR   GO; GO:0019896; P:axon transport of mitochondrion; IEA:Ensembl.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0042755; P:eating behavior; IEA:Ensembl.
DR   GO; GO:0048747; P:muscle fiber development; IEA:Ensembl.
DR   GO; GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
DR   GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:Ensembl.
//
ID   UCHL3_HUMAN             Reviewed;         230 AA.
AC   P15374; B2R970; Q5TBK8; Q6IBE9;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L3;
DE            Short=UCH-L3;
DE            EC=3.4.19.12;
DE   AltName: Full=Ubiquitin thioesterase L3;
GN   Name=UCHL3;
DR   GO; GO:0008233; F:peptidase activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043130; F:ubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; TAS:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IEA:InterPro.
DR   GO; GO:0030163; P:protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UCHL5_HUMAN             Reviewed;         329 AA.
AC   Q9Y5K5; Q5LJA6; Q5LJA7; Q8TBS4; Q96BJ9; Q9H1W5; Q9P0I3; Q9UQN2;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase isozyme L5;
DE            Short=UCH-L5;
DE            EC=3.4.19.12;
DE   AltName: Full=Ubiquitin C-terminal hydrolase UCH37;
DE   AltName: Full=Ubiquitin thioesterase L5;
GN   Name=UCHL5; Synonyms=UCH37; ORFNames=AD-019, CGI-70;
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; IMP:UniProtKB.
DR   GO; GO:0008242; F:omega peptidase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0070628; F:proteasome binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0048853; P:forebrain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021670; P:lateral ventricle development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IMP:GOC.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0061136; P:regulation of proteasomal protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   UCK1_HUMAN              Reviewed;         277 AA.
AC   Q9HA47; Q5JT10; Q5JT12; Q5JT13; Q6IA74; Q96BJ0;
DE   RecName: Full=Uridine-cytidine kinase 1;
DE            Short=UCK 1;
DE            EC=2.7.1.48;
DE   AltName: Full=Cytidine monophosphokinase 1;
DE   AltName: Full=Uridine monophosphokinase 1;
GN   Name=UCK1; Synonyms=URK1;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0004849; F:uridine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044211; P:CTP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
//
ID   UCMA_HUMAN              Reviewed;         138 AA.
AC   Q8WVF2;
DE   RecName: Full=Unique cartilage matrix-associated protein;
DE   Contains:
DE     RecName: Full=Unique cartilage matrix-associated protein C-terminal fragment;
DE              Short=Ucma-C;
DE     AltName: Full=Gla-rich protein;
DE              Short=GRP;
DE   Flags: Precursor;
GN   Name=UCMA; Synonyms=C10orf49;
DR   GO; GO:0045668; P:negative regulation of osteoblast differentiation; IEA:Ensembl.
//
ID   UCN2_HUMAN              Reviewed;         112 AA.
AC   Q96RP3; Q9BUG0;
DE   RecName: Full=Urocortin-2;
DE   AltName: Full=Stresscopin-related peptide;
DE   AltName: Full=Urocortin II;
DE            Short=Ucn II;
DE   AltName: Full=Urocortin-related peptide;
DE   Flags: Precursor;
GN   Name=UCN2; Synonyms=SRP, URP;
DR   GO; GO:0042562; F:hormone binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; NAS:UniProtKB.
DR   GO; GO:0046882; P:negative regulation of follicle-stimulating hormone secretion; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0033685; P:negative regulation of luteinizing hormone secretion; IEA:Ensembl.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   UCN3_HUMAN              Reviewed;         161 AA.
AC   Q969E3; Q496H2; Q5SR91;
DE   RecName: Full=Urocortin-3;
DE   AltName: Full=Stresscopin;
DE   AltName: Full=Urocortin III;
DE            Short=Ucn III;
DE   Flags: Precursor;
GN   Name=UCN3; Synonyms=SPC;
DR   GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0031669; P:cellular response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; IEA:InterPro.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0045838; P:positive regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0009749; P:response to glucose; IEA:Ensembl.
DR   GO; GO:0035902; P:response to immobilization stress; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
//
ID   UCK2_HUMAN              Reviewed;         261 AA.
AC   Q9BZX2; Q5VV91; Q7KZV3; Q92528; Q96KG5; Q9BU42;
DE   RecName: Full=Uridine-cytidine kinase 2;
DE            Short=UCK 2;
DE            EC=2.7.1.48;
DE   AltName: Full=Cytidine monophosphokinase 2;
DE   AltName: Full=Testis-specific protein TSA903;
DE   AltName: Full=Uridine monophosphokinase 2;
GN   Name=UCK2; Synonyms=UMPK;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019206; F:nucleoside kinase activity; EXP:Reactome.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0004849; F:uridine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0071453; P:cellular response to oxygen levels; IEA:Ensembl.
DR   GO; GO:0044211; P:CTP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0007631; P:feeding behavior; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
//
ID   UCP1_HUMAN              Reviewed;         307 AA.
AC   P25874; Q13218; Q4KMZ3; Q68G66;
DE   RecName: Full=Mitochondrial brown fat uncoupling protein 1;
DE            Short=UCP 1;
DE   AltName: Full=Solute carrier family 25 member 7;
DE   AltName: Full=Thermogenin;
GN   Name=UCP1; Synonyms=SLC25A7, UCP;
DR   GO; GO:0017077; F:oxidative phosphorylation uncoupler activity; IEA:Ensembl.
DR   GO; GO:0050873; P:brown fat cell differentiation; ISS:HGNC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR   GO; GO:0015992; P:proton transport; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   UCKL1_HUMAN             Reviewed;         548 AA.
AC   Q9NWZ5; B7Z8N2; Q5JWV0; Q70AQ5; Q8N524; Q9H3Z2;
DE   RecName: Full=Uridine-cytidine kinase-like 1;
DE            EC=2.7.1.48;
GN   Name=UCKL1; Synonyms=URKL1; ORFNames=F538;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004849; F:uridine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044211; P:CTP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UCN1_HUMAN              Reviewed;         124 AA.
AC   P55089; Q6FG64;
DE   RecName: Full=Urocortin;
DE   Flags: Precursor;
GN   Name=UCN;
DR   GO; GO:0046811; F:histone deacetylase inhibitor activity; IEA:Ensembl.
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034199; P:activation of protein kinase A activity; IEA:Ensembl.
DR   GO; GO:0009060; P:aerobic respiration; IEA:Ensembl.
DR   GO; GO:0008306; P:associative learning; IEA:Ensembl.
DR   GO; GO:0042756; P:drinking behavior; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0035483; P:gastric emptying; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0032099; P:negative regulation of appetite; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045792; P:negative regulation of cell size; IEA:Ensembl.
DR   GO; GO:2000252; P:negative regulation of feeding behavior; IEA:Ensembl.
DR   GO; GO:0060455; P:negative regulation of gastric acid secretion; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IEA:Ensembl.
DR   GO; GO:0060547; P:negative regulation of necrotic cell death; IEA:Ensembl.
DR   GO; GO:1901215; P:negative regulation of neuron death; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IEA:Ensembl.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:Ensembl.
DR   GO; GO:0030157; P:pancreatic juice secretion; IEA:Ensembl.
DR   GO; GO:2000987; P:positive regulation of behavioral fear response; IEA:Ensembl.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IEA:Ensembl.
DR   GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IEA:Ensembl.
DR   GO; GO:0060452; P:positive regulation of cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0051461; P:positive regulation of corticotropin secretion; IEA:Ensembl.
DR   GO; GO:0045740; P:positive regulation of DNA replication; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IEA:Ensembl.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:Ensembl.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0051966; P:regulation of synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0048265; P:response to pain; IEA:Ensembl.
//
ID   UCP2_HUMAN              Reviewed;         309 AA.
AC   P55851; Q4PJH8; Q53HM3;
DE   RecName: Full=Mitochondrial uncoupling protein 2;
DE            Short=UCP 2;
DE   AltName: Full=Solute carrier family 25 member 8;
DE   AltName: Full=UCPH;
GN   Name=UCP2; Synonyms=SLC25A8;
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0034198; P:cellular response to amino acid starvation; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0097421; P:liver regeneration; IEA:Ensembl.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0061179; P:negative regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0015992; P:proton transport; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0070542; P:response to fatty acid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0000303; P:response to superoxide; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006810; P:transport; NAS:ProtInc.
//
ID   UCP3_HUMAN              Reviewed;         312 AA.
AC   P55916; O60475; Q96HL3;
DE   RecName: Full=Mitochondrial uncoupling protein 3;
DE            Short=UCP 3;
DE   AltName: Full=Solute carrier family 25 member 9;
GN   Name=UCP3; Synonyms=SLC25A9;
DR   GO; GO:0017077; F:oxidative phosphorylation uncoupler activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0032870; P:cellular response to hormone stimulus; IEA:Ensembl.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:Ensembl.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR   GO; GO:0015992; P:proton transport; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0007585; P:respiratory gaseous exchange; TAS:ProtInc.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0000303; P:response to superoxide; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   UCP4_HUMAN              Reviewed;         323 AA.
AC   O95847; F5GWR4; Q5VTS9; Q8N518;
DE   RecName: Full=Mitochondrial uncoupling protein 4;
DE            Short=UCP 4;
DE   AltName: Full=Solute carrier family 25 member 27;
GN   Name=SLC25A27; Synonyms=UCP4; ORFNames=UNQ772/PRO1566;
DR   GO; GO:0035356; P:cellular triglyceride homeostasis; IEA:Ensembl.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0048839; P:inner ear development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0051562; P:negative regulation of mitochondrial calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010917; P:negative regulation of mitochondrial membrane potential; IEA:Ensembl.
DR   GO; GO:0070997; P:neuron death; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0046324; P:regulation of glucose import; IEA:Ensembl.
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   UCP5_HUMAN              Reviewed;         325 AA.
AC   O95258; D3DTG2; Q0VDH7; Q9HC60; Q9HC61;
DE   RecName: Full=Brain mitochondrial carrier protein 1;
DE            Short=BMCP-1;
DE   AltName: Full=Mitochondrial uncoupling protein 5;
DE            Short=UCP 5;
DE   AltName: Full=Solute carrier family 25 member 14;
GN   Name=SLC25A14; Synonyms=BMCP1, UCP5; ORFNames=UNQ791/PRO1682;
DR   GO; GO:0009060; P:aerobic respiration; TAS:ProtInc.
DR   GO; GO:0006839; P:mitochondrial transport; IEA:InterPro.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   UCRIL_HUMAN             Reviewed;         283 AA.
AC   P0C7P4;
DE   RecName: Full=Putative cytochrome b-c1 complex subunit Rieske-like protein 1;
DE   AltName: Full=Ubiquinol-cytochrome c reductase Rieske iron-sulfur subunit pseudogene 1;
GN   Name=UQCRFS1P1; Synonyms=UQCRFSL1;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro.
//
ID   UCRI_HUMAN              Reviewed;         274 AA.
AC   P47985; A8K519; Q6NVX5; Q9UPH2;
DE   RecName: Full=Cytochrome b-c1 complex subunit Rieske, mitochondrial;
DE            EC=1.10.2.2;
DE   AltName: Full=Complex III subunit 5;
DE   AltName: Full=Cytochrome b-c1 complex subunit 5;
DE   AltName: Full=Rieske iron-sulfur protein;
DE            Short=RISP;
DE   AltName: Full=Ubiquinol-cytochrome c reductase iron-sulfur subunit;
DE   Contains:
DE     RecName: Full=Cytochrome b-c1 complex subunit 11;
DE     AltName: Full=Complex III subunit IX;
DE     AltName: Full=Ubiquinol-cytochrome c reductase 8 kDa protein;
DE   Flags: Precursor;
GN   Name=UQCRFS1;
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0044237; P:cellular metabolic process; TAS:Reactome.
DR   GO; GO:0022904; P:respiratory electron transport chain; TAS:Reactome.
DR   GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0009725; P:response to hormone; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   UD110_HUMAN             Reviewed;         530 AA.
AC   Q9HAW8; O00474; Q6NT91; Q7Z6H8;
DE   RecName: Full=UDP-glucuronosyltransferase 1-10;
DE            Short=UDPGT 1-10;
DE            Short=UGT1*10;
DE            Short=UGT1-10;
DE            Short=UGT1.10;
DE            EC=2.4.1.17;
DE   AltName: Full=UDP-glucuronosyltransferase 1-J;
DE            Short=UGT-1J;
DE            Short=UGT1J;
DE   AltName: Full=UDP-glucuronosyltransferase 1A10;
DE   Flags: Precursor;
GN   Name=UGT1A10; Synonyms=GNT1, UGT1;
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.
DR   GO; GO:0052695; P:cellular glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0051552; P:flavone metabolic process; IDA:BHF-UCL.
//
ID   UD11_HUMAN              Reviewed;         533 AA.
AC   P22309; A6NJC3; B8K286;
DE   RecName: Full=UDP-glucuronosyltransferase 1-1;
DE            Short=UDPGT 1-1;
DE            Short=UGT1*1;
DE            Short=UGT1-01;
DE            Short=UGT1.1;
DE            EC=2.4.1.17;
DE   AltName: Full=Bilirubin-specific UDPGT isozyme 1;
DE            Short=hUG-BR1;
DE   AltName: Full=UDP-glucuronosyltransferase 1-A;
DE            Short=UGT-1A;
DE            Short=UGT1A;
DE   AltName: Full=UDP-glucuronosyltransferase 1A1;
DE   Flags: Precursor;
GN   Name=UGT1A1; Synonyms=GNT1, UGT1;
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0005496; F:steroid binding; IDA:BHF-UCL.
DR   GO; GO:0006953; P:acute-phase response; IEA:Ensembl.
DR   GO; GO:0006789; P:bilirubin conjugation; TAS:ProtInc.
DR   GO; GO:0070980; P:biphenyl catabolic process; IEA:Ensembl.
DR   GO; GO:0052695; P:cellular glucuronidation; TAS:Reactome.
DR   GO; GO:0071361; P:cellular response to ethanol; IEA:Ensembl.
DR   GO; GO:0071385; P:cellular response to glucocorticoid stimulus; IEA:Ensembl.
DR   GO; GO:0007586; P:digestion; NAS:ProtInc.
DR   GO; GO:0017144; P:drug metabolic process; IC:BHF-UCL.
DR   GO; GO:0008210; P:estrogen metabolic process; TAS:ProtInc.
DR   GO; GO:0051552; P:flavone metabolic process; IDA:BHF-UCL.
DR   GO; GO:0052696; P:flavonoid glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0042167; P:heme catabolic process; TAS:Reactome.
DR   GO; GO:0046483; P:heterocycle metabolic process; IC:BHF-UCL.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:2001030; P:negative regulation of cellular glucuronidation; IDA:UniProtKB.
DR   GO; GO:0045939; P:negative regulation of steroid metabolic process; IC:BHF-UCL.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0006778; P:porphyrin-containing compound metabolic process; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; IC:BHF-UCL.
DR   GO; GO:0052697; P:xenobiotic glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   UD13_HUMAN              Reviewed;         534 AA.
AC   P35503; B8K287;
DE   RecName: Full=UDP-glucuronosyltransferase 1-3;
DE            Short=UDPGT 1-3;
DE            Short=UGT1*3;
DE            Short=UGT1-03;
DE            Short=UGT1.3;
DE            EC=2.4.1.17;
DE   AltName: Full=UDP-glucuronosyltransferase 1-C;
DE            Short=UGT-1C;
DE            Short=UGT1C;
DE   AltName: Full=UDP-glucuronosyltransferase 1A3;
DE   Flags: Precursor;
GN   Name=UGT1A3; Synonyms=GNT1, UGT1;
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; TAS:ProtInc.
DR   GO; GO:0052696; P:flavonoid glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IC:BHF-UCL.
DR   GO; GO:0052697; P:xenobiotic glucuronidation; IDA:BHF-UCL.
//
ID   UD14_HUMAN              Reviewed;         534 AA.
AC   P22310; B2R937; B8K288; Q5DT00;
DE   RecName: Full=UDP-glucuronosyltransferase 1-4;
DE            Short=UDPGT 1-4;
DE            Short=UGT1*4;
DE            Short=UGT1-04;
DE            Short=UGT1.4;
DE            EC=2.4.1.17;
DE   AltName: Full=Bilirubin-specific UDPGT isozyme 2;
DE            Short=hUG-BR2;
DE   AltName: Full=UDP-glucuronosyltransferase 1-D;
DE            Short=UGT-1D;
DE            Short=UGT1D;
DE   AltName: Full=UDP-glucuronosyltransferase 1A4;
DE   Flags: Precursor;
GN   Name=UGT1A4; Synonyms=GNT1, UGT1;
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0052695; P:cellular glucuronidation; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   UD16_HUMAN              Reviewed;         532 AA.
AC   P19224; A6NKK6; B8K289; Q96TE7;
DE   RecName: Full=UDP-glucuronosyltransferase 1-6;
DE            Short=UDPGT 1-6;
DE            Short=UGT1*6;
DE            Short=UGT1-06;
DE            Short=UGT1.6;
DE            EC=2.4.1.17;
DE   AltName: Full=Phenol-metabolizing UDP-glucuronosyltransferase;
DE   AltName: Full=UDP-glucuronosyltransferase 1-F;
DE            Short=UGT-1F;
DE            Short=UGT1F;
DE   AltName: Full=UDP-glucuronosyltransferase 1A6;
DE   Flags: Precursor;
GN   Name=UGT1A6; Synonyms=GNT1, UGT1;
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0052695; P:cellular glucuronidation; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   UD17_HUMAN              Reviewed;         530 AA.
AC   Q9HAW7; B8K293; O00473;
DE   RecName: Full=UDP-glucuronosyltransferase 1-7;
DE            Short=UDPGT 1-7;
DE            Short=UGT1*7;
DE            Short=UGT1-07;
DE            Short=UGT1.7;
DE            EC=2.4.1.17;
DE   AltName: Full=UDP-glucuronosyltransferase 1-G;
DE            Short=UGT-1G;
DE            Short=UGT1G;
DE   AltName: Full=UDP-glucuronosyltransferase 1A7;
DE   Flags: Precursor;
GN   Name=UGT1A7; Synonyms=GNT1, UGT1;
DR   GO; GO:0008144; F:drug binding; IDA:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0005080; F:protein kinase C binding; IPI:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0009804; P:coumarin metabolic process; IC:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0007588; P:excretion; IC:BHF-UCL.
DR   GO; GO:0051552; P:flavone metabolic process; IC:BHF-UCL.
DR   GO; GO:0052696; P:flavonoid glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:2001030; P:negative regulation of cellular glucuronidation; IDA:UniProtKB.
DR   GO; GO:0045922; P:negative regulation of fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IC:BHF-UCL.
DR   GO; GO:0052697; P:xenobiotic glucuronidation; IDA:BHF-UCL.
//
ID   UD15_HUMAN              Reviewed;         534 AA.
AC   P35504; B8K294;
DE   RecName: Full=UDP-glucuronosyltransferase 1-5;
DE            Short=UDPGT 1-5;
DE            Short=UGT1*5;
DE            Short=UGT1-05;
DE            Short=UGT1.5;
DE            EC=2.4.1.17;
DE   AltName: Full=UDP-glucuronosyltransferase 1-E;
DE            Short=UGT-1E;
DE            Short=UGT1E;
DE   AltName: Full=UDP-glucuronosyltransferase 1A5;
DE   Flags: Precursor;
GN   Name=UGT1A5; Synonyms=GNT1, UGT1;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
//
ID   UD18_HUMAN              Reviewed;         530 AA.
AC   Q9HAW9; B2R8S3; B8K290; O14928; Q8TEX4; Q8WTQ9; Q8WX85;
DE   RecName: Full=UDP-glucuronosyltransferase 1-8;
DE            Short=UDPGT 1-8;
DE            Short=UGT1*8;
DE            Short=UGT1-08;
DE            Short=UGT1.8;
DE            EC=2.4.1.17;
DE   AltName: Full=UDP-glucuronosyltransferase 1-H;
DE            Short=UGT-1H;
DE            Short=UGT1H;
DE   AltName: Full=UDP-glucuronosyltransferase 1A8;
DE   Flags: Precursor;
GN   Name=UGT1A8; Synonyms=GNT1, UGT1;
DR   GO; GO:0008144; F:drug binding; IC:BHF-UCL.
DR   GO; GO:0019899; F:enzyme binding; IC:BHF-UCL.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0005504; F:fatty acid binding; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IC:BHF-UCL.
DR   GO; GO:0005496; F:steroid binding; IDA:BHF-UCL.
DR   GO; GO:0009804; P:coumarin metabolic process; IC:BHF-UCL.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0006631; P:fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051552; P:flavone metabolic process; IDA:BHF-UCL.
DR   GO; GO:0052696; P:flavonoid glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:2001030; P:negative regulation of cellular glucuronidation; IDA:UniProtKB.
DR   GO; GO:0031324; P:negative regulation of cellular metabolic process; IDA:BHF-UCL.
DR   GO; GO:0045922; P:negative regulation of fatty acid metabolic process; IC:BHF-UCL.
DR   GO; GO:0045939; P:negative regulation of steroid metabolic process; IC:BHF-UCL.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IC:BHF-UCL.
DR   GO; GO:0008202; P:steroid metabolic process; IC:BHF-UCL.
DR   GO; GO:0052697; P:xenobiotic glucuronidation; IDA:BHF-UCL.
//
ID   UD19_HUMAN              Reviewed;         530 AA.
AC   O60656; B8K285; P36509; Q9HAX0;
DE   RecName: Full=UDP-glucuronosyltransferase 1-9;
DE            Short=UDPGT 1-9;
DE            Short=UGT1*9;
DE            Short=UGT1-09;
DE            Short=UGT1.9;
DE            EC=2.4.1.17;
DE   AltName: Full=UDP-glucuronosyltransferase 1-I;
DE            Short=UGT-1I;
DE            Short=UGT1I;
DE   AltName: Full=UDP-glucuronosyltransferase 1A9;
DE   AltName: Full=lugP4;
DE   Flags: Precursor;
GN   Name=UGT1A9; Synonyms=GNT1, UGT1;
DR   GO; GO:0019899; F:enzyme binding; IDA:BHF-UCL.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IDA:BHF-UCL.
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
DR   GO; GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
DR   GO; GO:0017144; P:drug metabolic process; IDA:BHF-UCL.
DR   GO; GO:0051552; P:flavone metabolic process; IDA:BHF-UCL.
DR   GO; GO:0052696; P:flavonoid glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0008152; P:metabolic process; TAS:ProtInc.
DR   GO; GO:0043086; P:negative regulation of catalytic activity; IDA:GOC.
DR   GO; GO:2001030; P:negative regulation of cellular glucuronidation; IDA:UniProtKB.
DR   GO; GO:0045922; P:negative regulation of fatty acid metabolic process; IDA:BHF-UCL.
DR   GO; GO:0042573; P:retinoic acid metabolic process; IC:BHF-UCL.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0052697; P:xenobiotic glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   UD2A1_HUMAN             Reviewed;         527 AA.
AC   Q9Y4X1; B4E2F4; D3GER1; D3GER2; E9PDM7; J3KNA3;
DE   RecName: Full=UDP-glucuronosyltransferase 2A1;
DE            Short=UDPGT 2A1;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT2A1; Synonyms=UGT2A2;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0052695; P:cellular glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0009593; P:detection of chemical stimulus; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
//
ID   UD2A3_HUMAN             Reviewed;         527 AA.
AC   Q6UWM9; Q9H6S4;
DE   RecName: Full=UDP-glucuronosyltransferase 2A3;
DE            Short=UDPGT 2A3;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT2A3; ORFNames=UNQ2559/PRO6239;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0052695; P:cellular glucuronidation; IDA:BHF-UCL.
//
ID   UD2B4_HUMAN             Reviewed;         528 AA.
AC   P06133; O60731; O60867; O75614; P36538; Q1HBF9;
DE   RecName: Full=UDP-glucuronosyltransferase 2B4;
DE            Short=UDPGT 2B4;
DE            EC=2.4.1.17;
DE   AltName: Full=HLUG25;
DE   AltName: Full=Hyodeoxycholic acid-specific UDPGT;
DE   AltName: Full=UDPGTh-1;
DE   Flags: Precursor;
GN   Name=UGT2B4; Synonyms=UGT2B11;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0052695; P:cellular glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0006711; P:estrogen catabolic process; IDA:UniProtKB.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   UD2B7_HUMAN             Reviewed;         529 AA.
AC   P16662; B2R810; Q6GTW0;
DE   RecName: Full=UDP-glucuronosyltransferase 2B7;
DE            Short=UDPGT 2B7;
DE            EC=2.4.1.17;
DE   AltName: Full=3,4-catechol estrogen-specific UDPGT;
DE   AltName: Full=UDP-glucuronosyltransferase 2B9;
DE            Short=UDPGT 2B9;
DE   AltName: Full=UDPGTh-2;
DE   Flags: Precursor;
GN   Name=UGT2B7; Synonyms=UGTB2B9;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0008209; P:androgen metabolic process; IDA:UniProtKB.
DR   GO; GO:0052695; P:cellular glucuronidation; IDA:UniProtKB.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
//
ID   UD3A1_HUMAN             Reviewed;         523 AA.
AC   Q6NUS8; G5E961; Q8IYS9; Q8NAW4; Q96DM6;
DE   RecName: Full=UDP-glucuronosyltransferase 3A1;
DE            Short=UDPGT 3A1;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT3A1;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:MGI.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IDA:MGI.
//
ID   UD3A2_HUMAN             Reviewed;         523 AA.
AC   Q3SY77; B4DUQ7; E9PFK7; Q6UXC4; Q8NBP2;
DE   RecName: Full=UDP-glucuronosyltransferase 3A2;
DE            Short=UDPGT 3A2;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT3A2; ORFNames=PSEC0073, UNQ842/PRO1780;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008194; F:UDP-glycosyltransferase activity; IDA:MGI.
DR   GO; GO:0071412; P:cellular response to genistein; IDA:MGI.
//
ID   UDB10_HUMAN             Reviewed;         528 AA.
AC   P36537; A8K9M3; B4DPP1; Q14CR8;
DE   RecName: Full=UDP-glucuronosyltransferase 2B10;
DE            Short=UDPGT 2B10;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT2B10;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
//
ID   UDB11_HUMAN             Reviewed;         529 AA.
AC   O75310; Q3KNV9;
DE   RecName: Full=UDP-glucuronosyltransferase 2B11;
DE            Short=UDPGT 2B11;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT2B11;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008210; P:estrogen metabolic process; TAS:ProtInc.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:ProtInc.
//
ID   UDB15_HUMAN             Reviewed;         530 AA.
AC   P54855; A6NDX0; A6NNJ4; A8K054; P23765; Q9UK63;
DE   RecName: Full=UDP-glucuronosyltransferase 2B15;
DE            Short=UDPGT 2B15;
DE            EC=2.4.1.17;
DE   AltName: Full=HLUG4;
DE   AltName: Full=UDP-glucuronosyltransferase 2B8;
DE            Short=UDPGT 2B8;
DE   AltName: Full=UDPGTh-3;
DE   Flags: Precursor;
GN   Name=UGT2B15; Synonyms=UGT2B8;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IDA:BHF-UCL.
DR   GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro.
DR   GO; GO:0052695; P:cellular glucuronidation; IDA:BHF-UCL.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:ProtInc.
//
ID   UDB17_HUMAN             Reviewed;         530 AA.
AC   O75795;
DE   RecName: Full=UDP-glucuronosyltransferase 2B17;
DE            Short=UDPGT 2B17;
DE            EC=2.4.1.17;
DE   AltName: Full=C19-steroid-specific UDP-glucuronosyltransferase;
DE            Short=C19-steroid-specific UDPGT;
DE   Flags: Precursor;
GN   Name=UGT2B17;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:ProtInc.
//
ID   UDB28_HUMAN             Reviewed;         529 AA.
AC   Q9BY64; B5BUM0; Q9BY62; Q9BY63;
DE   RecName: Full=UDP-glucuronosyltransferase 2B28;
DE            Short=UDPGT 2B28;
DE            EC=2.4.1.17;
DE   Flags: Precursor;
GN   Name=UGT2B28;
DR   GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IDA:UniProtKB.
DR   GO; GO:0006805; P:xenobiotic metabolic process; IDA:UniProtKB.
//
ID   UE2NL_HUMAN             Reviewed;         153 AA.
AC   Q5JXB2; E9KL27;
DE   RecName: Full=Putative ubiquitin-conjugating enzyme E2 N-like;
DE   AltName: Full=Epididymis tissue protein Li 174;
GN   Name=UBE2NL;
DR   GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
//
ID   UEVLD_HUMAN             Reviewed;         471 AA.
AC   Q8IX04; B2RB69; B4DL43; F5H6L6; H7BYD6; Q6P2F0; Q96FF5; Q9NUX7;
DE   RecName: Full=Ubiquitin-conjugating enzyme E2 variant 3;
DE            Short=UEV-3;
DE   AltName: Full=EV and lactate/malate dehydrogenase domain-containing protein;
GN   Name=UEVLD; Synonyms=UEV3;
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006464; P:cellular protein modification process; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
//
ID   UFC1_HUMAN              Reviewed;         167 AA.
AC   Q9Y3C8; A8K9R1; D3DVF9; Q549X0; Q5VTX1; Q9BS96; Q9P009;
DE   RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1;
DE            Short=Ufm1-conjugating enzyme 1;
GN   Name=UFC1; ORFNames=CGI-126, HSPC155;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071568; F:UFM1 conjugating enzyme activity; IDA:UniProtKB.
DR   GO; GO:0071569; P:protein ufmylation; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:MGI.
//
ID   UFD1_HUMAN              Reviewed;         307 AA.
AC   Q92890; A8MW31; Q9Y5N0;
DE   RecName: Full=Ubiquitin fusion degradation protein 1 homolog;
DE            Short=UB fusion protein 1;
GN   Name=UFD1L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001501; P:skeletal system development; TAS:ProtInc.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
//
ID   UFL1_HUMAN              Reviewed;         794 AA.
AC   O94874; A0PJ53; B4DJ57; C0H5X5; Q8N765; Q9NTQ0;
DE   RecName: Full=E3 UFM1-protein ligase 1;
DE            EC=6.3.2.-;
DE   AltName: Full=LZAP-binding protein;
GN   Name=UFL1; Synonyms=KIAA0776, NLBP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071568; F:UFM1 conjugating enzyme activity; IDA:UniProtKB.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0071569; P:protein ufmylation; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:MGI.
//
ID   UFM1_HUMAN              Reviewed;          85 AA.
AC   P61960; Q14346; Q5VXS0; Q6IAG6; Q9CPX2; Q9NZF2;
DE   RecName: Full=Ubiquitin-fold modifier 1;
DE   Flags: Precursor;
GN   Name=UFM1; Synonyms=C13orf20; ORFNames=BM-002;
DR   GO; GO:0071569; P:protein ufmylation; IDA:UniProtKB.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:MGI.
//
ID   UFO_HUMAN               Reviewed;         894 AA.
AC   P30530; Q8N5L2; Q9UD27;
DE   RecName: Full=Tyrosine-protein kinase receptor UFO;
DE            EC=2.7.10.1;
DE   AltName: Full=AXL oncogene;
DE   Flags: Precursor;
GN   Name=AXL; Synonyms=UFO;
DR   GuidetoPHARMACOLOGY; 1835; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0043277; P:apoptotic cell clearance; IEA:Ensembl.
DR   GO; GO:0001974; P:blood vessel remodeling; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEP:UniProtKB.
DR   GO; GO:0031668; P:cellular response to extracellular stimulus; IEA:Ensembl.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IEA:Ensembl.
DR   GO; GO:0035457; P:cellular response to interferon-alpha; IDA:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:UniProtKB.
DR   GO; GO:0097028; P:dendritic cell differentiation; IEP:UniProtKB.
DR   GO; GO:0007167; P:enzyme linked receptor protein signaling pathway; IEA:Ensembl.
DR   GO; GO:0034101; P:erythrocyte homeostasis; IEA:Ensembl.
DR   GO; GO:0021885; P:forebrain cell migration; IEA:Ensembl.
DR   GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:2000669; P:negative regulation of dendritic cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:UniProtKB.
DR   GO; GO:0051250; P:negative regulation of lymphocyte activation; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0042698; P:ovulation cycle; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; TAS:GOC.
DR   GO; GO:0006909; P:phagocytosis; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; IEA:Ensembl.
DR   GO; GO:0001961; P:positive regulation of cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0043491; P:protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0032940; P:secretion by cell; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Ensembl.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
//
ID   UFSP1_HUMAN             Reviewed;         142 AA.
AC   Q6NVU6; A4D2E4; A8K8V2; B6ZDG6; Q9BXP6;
DE   RecName: Full=Inactive Ufm1-specific protease 1;
DE            Short=UfSP1;
GN   Name=UFSP1;
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:Ensembl.
DR   GO; GO:0071567; F:UFM1 hydrolase activity; IEA:Ensembl.
//
ID   UFSP2_HUMAN             Reviewed;         469 AA.
AC   Q9NUQ7; Q6IA77; Q96FS3;
DE   RecName: Full=Ufm1-specific protease 2;
DE            Short=UfSP2;
DE            EC=3.4.22.-;
GN   Name=UFSP2; Synonyms=C4orf20;
DR   GO; GO:0019783; F:small conjugating protein-specific protease activity; ISS:UniProtKB.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:Ensembl.
//
ID   UGDH_HUMAN              Reviewed;         494 AA.
AC   O60701; B3KUU2; B4DN25; O60589;
DE   RecName: Full=UDP-glucose 6-dehydrogenase;
DE            Short=UDP-Glc dehydrogenase;
DE            Short=UDP-GlcDH;
DE            Short=UDPGDH;
DE            EC=1.1.1.22;
GN   Name=UGDH;
DR   GO; GO:0009055; F:electron carrier activity; TAS:UniProtKB.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0003979; F:UDP-glucose 6-dehydrogenase activity; TAS:Reactome.
DR   GO; GO:0052695; P:cellular glucuronidation; TAS:Reactome.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006011; P:UDP-glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0006065; P:UDP-glucuronate biosynthetic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   UGGG1_HUMAN             Reviewed;        1555 AA.
AC   Q9NYU2; Q53QP2; Q53SL3; Q8IW30; Q9H8I4;
DE   RecName: Full=UDP-glucose:glycoprotein glucosyltransferase 1;
DE            Short=UGT1;
DE            Short=hUGT1;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP--Glc:glycoprotein glucosyltransferase;
DE   AltName: Full=UDP-glucose ceramide glucosyltransferase-like 1;
DE   Flags: Precursor;
GN   Name=UGGT1; Synonyms=GT, UGCGL1, UGGT, UGT1, UGTR;
DR   GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; IDA:UniProtKB.
DR   GO; GO:0051084; P:'de novo' posttranslational protein folding; TAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
//
ID   UGGG2_HUMAN             Reviewed;        1516 AA.
AC   Q9NYU1; Q08AD0; Q5JQR8; Q9UFC4;
DE   RecName: Full=UDP-glucose:glycoprotein glucosyltransferase 2;
DE            Short=UGT2;
DE            Short=hUGT2;
DE            EC=2.4.1.-;
DE   AltName: Full=UDP--Glc:glycoprotein glucosyltransferase 2;
DE   AltName: Full=UDP-glucose ceramide glucosyltransferase-like 1;
DE   Flags: Precursor;
GN   Name=UGGT2; Synonyms=UGCGL2, UGT2;
DR   GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0006457; P:protein folding; TAS:Reactome.
DR   GO; GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
DR   GO; GO:0097359; P:UDP-glucosylation; ISS:GOC.
//
ID   UGPA_HUMAN              Reviewed;         508 AA.
AC   Q16851; Q07131; Q0P6K2; Q86Y81; Q9BU15;
DE   RecName: Full=UTP--glucose-1-phosphate uridylyltransferase;
DE            EC=2.7.7.9;
DE   AltName: Full=UDP-glucose pyrophosphorylase;
DE            Short=UDPGP;
DE            Short=UGPase;
GN   Name=UGP2; Synonyms=UGP1;
DR   GO; GO:0005536; F:glucose binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032557; F:pyrimidine ribonucleotide binding; IEA:Ensembl.
DR   GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0052695; P:cellular glucuronidation; TAS:Reactome.
DR   GO; GO:0019255; P:glucose 1-phosphate metabolic process; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; TAS:Reactome.
DR   GO; GO:0005978; P:glycogen biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006011; P:UDP-glucose metabolic process; TAS:ProtInc.
DR   GO; GO:0006065; P:UDP-glucuronate biosynthetic process; TAS:Reactome.
DR   GO; GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
//
ID   UH1BL_HUMAN             Reviewed;        1464 AA.
AC   A0JNW5; A0PJE5; O75183; Q8NDL1; Q96C30; Q9BTS5; Q9H0F1;
DE   RecName: Full=UHRF1-binding protein 1-like;
GN   Name=UHRF1BP1L; Synonyms=KIAA0701;
//
ID   UHMK1_HUMAN             Reviewed;         419 AA.
AC   Q8TAS1; A8K8K4; G3V1M1; Q96C22;
DE   RecName: Full=Serine/threonine-protein kinase Kist;
DE            EC=2.7.11.1;
DE   AltName: Full=Kinase interacting with stathmin;
DE   AltName: Full=PAM COOH-terminal interactor protein 2;
DE            Short=P-CIP2;
DE   AltName: Full=U2AF homology motif kinase 1;
GN   Name=UHMK1; Synonyms=KIS, KIST;
DR   GO; GO:0005524; F:ATP binding; IC:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:HGNC.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; ISS:BHF-UCL.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IC:HGNC.
DR   GO; GO:0007050; P:cell cycle arrest; IMP:HGNC.
DR   GO; GO:0031175; P:neuron projection development; ISS:BHF-UCL.
DR   GO; GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.
DR   GO; GO:0045948; P:positive regulation of translational initiation; ISS:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:HGNC.
DR   GO; GO:0046825; P:regulation of protein export from nucleus; IDA:HGNC.
//
ID   UHRF1_HUMAN             Reviewed;         793 AA.
AC   Q96T88; A0JBR2; A8K024; B2RBA9; Q2HIX7; Q8J022; Q9H6S6; Q9P115;
AC   Q9P1U7;
DE   RecName: Full=E3 ubiquitin-protein ligase UHRF1;
DE            EC=6.3.2.-;
DE   AltName: Full=Inverted CCAAT box-binding protein of 90 kDa;
DE   AltName: Full=Nuclear protein 95;
DE   AltName: Full=Nuclear zinc finger protein Np95;
DE            Short=HuNp95;
DE            Short=hNp95;
DE   AltName: Full=RING finger protein 106;
DE   AltName: Full=Transcription factor ICBP90;
DE   AltName: Full=Ubiquitin-like PHD and RING finger domain-containing protein 1;
DE            Short=hUHRF1;
DE   AltName: Full=Ubiquitin-like-containing PHD and RING finger domains protein 1;
GN   Name=UHRF1; Synonyms=ICBP90, NP95, RNF106;
DR   GO; GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0044729; F:hemi-methylated DNA-binding; IDA:UniProtKB.
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; ISS:BHF-UCL.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0031493; F:nucleosomal histone binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEP:BHF-UCL.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0010390; P:histone monoubiquitination; ISS:BHF-UCL.
DR   GO; GO:0016574; P:histone ubiquitination; IDA:UniProtKB.
DR   GO; GO:0010216; P:maintenance of DNA methylation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:2000373; P:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   UHRF2_HUMAN             Reviewed;         802 AA.
AC   Q96PU4; Q5VYR1; Q5VYR3; Q659C8; Q8TAG7;
DE   RecName: Full=E3 ubiquitin-protein ligase UHRF2;
DE            EC=6.3.2.-;
DE   AltName: Full=Np95/ICBP90-like RING finger protein;
DE            Short=Np95-like RING finger protein;
DE   AltName: Full=Nuclear protein 97;
DE   AltName: Full=Nuclear zinc finger protein Np97;
DE   AltName: Full=RING finger protein 107;
DE   AltName: Full=Ubiquitin-like PHD and RING finger domain-containing protein 2;
DE   AltName: Full=Ubiquitin-like-containing PHD and RING finger domains protein 2;
GN   Name=UHRF2; Synonyms=NIRF, RNF107;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042393; F:histone binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:HGNC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEP:HGNC.
DR   GO; GO:0008283; P:cell proliferation; IEP:HGNC.
DR   GO; GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:HGNC.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:HGNC.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:HGNC.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:HGNC.
//
ID   UIF_HUMAN               Reviewed;         318 AA.
AC   Q96QD9; A8MY74; B2RCB2; B7Z3R4; B7Z7V1; B7Z8I0; B7ZAJ3; C9J7P6;
AC   C9JNG6; C9JTH3; C9JY50; Q96SL9; Q9BQI8;
DE   RecName: Full=UAP56-interacting factor;
DE   AltName: Full=Forty-two-three domain-containing protein 1;
DE            Short=Protein 40-2-3;
GN   Name=FYTTD1; Synonyms=UIF;
DR   GO; GO:0003729; F:mRNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006406; P:mRNA export from nucleus; IMP:UniProtKB.
//
ID   UIMC1_HUMAN             Reviewed;         719 AA.
AC   Q96RL1; A8MSA1; B3KMZ1; B4E3N2; Q5XKQ1; Q7Z3W7; Q8N5B9; Q9BZR1;
AC   Q9BZR5; Q9UHX7;
DE   RecName: Full=BRCA1-A complex subunit RAP80;
DE   AltName: Full=Receptor-associated protein 80;
DE   AltName: Full=Retinoid X receptor-interacting protein 110;
DE   AltName: Full=Ubiquitin interaction motif-containing protein 1;
GN   Name=UIMC1; Synonyms=RAP80, RXRIP110;
DR   GO; GO:0042393; F:histone binding; IDA:UniProtKB.
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0031572; P:G2 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0070537; P:histone H2A K63-linked deubiquitination; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:HGNC.
DR   GO; GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.
DR   GO; GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   UK114_HUMAN             Reviewed;         137 AA.
AC   P52758; Q6FHU9; Q6IBG0;
DE   RecName: Full=Ribonuclease UK114;
DE            EC=3.1.-.-;
DE   AltName: Full=14.5 kDa translational inhibitor protein;
DE            Short=p14.5;
DE   AltName: Full=Heat-responsive protein 12;
DE   AltName: Full=UK114 antigen homolog;
GN   Name=HRSP12; Synonyms=PSP;
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006449; P:regulation of translational termination; TAS:ProtInc.
//
ID   UL17C_HUMAN             Reviewed;         530 AA.
AC   C9JPN9;
DE   RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 12;
DE            EC=3.4.19.12;
GN   Name=USP17L12;
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   ULA1_HUMAN              Reviewed;         534 AA.
AC   Q13564; A6NCK0; A6NFN4; A8MU28; B2R700; B3KUP9;
DE   RecName: Full=NEDD8-activating enzyme E1 regulatory subunit;
DE   AltName: Full=Amyloid beta precursor protein-binding protein 1, 59 kDa;
DE            Short=APP-BP1;
DE   AltName: Full=Amyloid protein-binding protein 1;
DE   AltName: Full=Proto-oncogene protein 1;
GN   Name=NAE1; Synonyms=APPBP1; ORFNames=HPP1;
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0033314; P:mitotic DNA replication checkpoint; IDA:UniProtKB.
DR   GO; GO:0051402; P:neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0045116; P:protein neddylation; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0043523; P:regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   ULK1_HUMAN              Reviewed;        1050 AA.
AC   O75385; Q9UQ28;
DE   RecName: Full=Serine/threonine-protein kinase ULK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Autophagy-related protein 1 homolog;
DE            Short=ATG1;
DE            Short=hATG1;
DE   AltName: Full=Unc-51-like kinase 1;
GN   Name=ULK1; Synonyms=KIAA0722;
DR   GuidetoPHARMACOLOGY; 2271; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0017137; F:Rab GTPase binding; IPI:BHF-UCL.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IEA:Ensembl.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; IEA:Ensembl.
DR   GO; GO:0048671; P:negative regulation of collateral sprouting; IEA:Ensembl.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0031102; P:neuron projection regeneration; IEA:Ensembl.
DR   GO; GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0008104; P:protein localization; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; NAS:UniProtKB.
DR   GO; GO:0021933; P:radial glia guided migration of cerebellar granule cell; IEA:Ensembl.
DR   GO; GO:0007265; P:Ras protein signal transduction; IEA:Ensembl.
DR   GO; GO:0031623; P:receptor internalization; IEA:Ensembl.
DR   GO; GO:0010506; P:regulation of autophagy; IDA:UniProtKB.
DR   GO; GO:0051386; P:regulation of neurotrophin TRK receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; ISS:UniProtKB.
//
ID   ULK2_HUMAN              Reviewed;        1036 AA.
AC   Q8IYT8; A8MY69; O75119;
DE   RecName: Full=Serine/threonine-protein kinase ULK2;
DE            EC=2.7.11.1;
DE   AltName: Full=Unc-51-like kinase 2;
GN   Name=ULK2; Synonyms=KIAA0623;
DR   GuidetoPHARMACOLOGY; 2272; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR   GO; GO:0048671; P:negative regulation of collateral sprouting; IEA:Ensembl.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0010506; P:regulation of autophagy; IDA:UniProtKB.
DR   GO; GO:0042594; P:response to starvation; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   ULK4_HUMAN              Reviewed;        1275 AA.
AC   Q96C45; A6NF15; Q8IW79; Q9NWV6; Q9UF96;
DE   RecName: Full=Serine/threonine-protein kinase ULK4;
DE            EC=2.7.11.1;
DE   AltName: Full=Unc-51-like kinase 4;
GN   Name=ULK4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0003351; P:epithelial cilium movement; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
//
ID   ULK3_HUMAN              Reviewed;         472 AA.
AC   Q6PHR2; B2RXK3; B4DRQ7; D3DW68; Q9NPN5; Q9UFS4;
DE   RecName: Full=Serine/threonine-protein kinase ULK3;
DE            EC=2.7.11.1;
DE   AltName: Full=Unc-51-like kinase 3;
GN   Name=ULK3;
DR   GuidetoPHARMACOLOGY; 2273; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; TAS:UniProtKB.
DR   GO; GO:0090398; P:cellular senescence; TAS:UniProtKB.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
//
ID   UMPS_HUMAN              Reviewed;         480 AA.
AC   P11172; B5LY68; B5LY72; O00758; O00759; O00760; Q16862; Q9H3Q2;
AC   Q9UG49;
DE   RecName: Full=Uridine 5'-monophosphate synthase;
DE            Short=UMP synthase;
DE   Includes:
DE     RecName: Full=Orotate phosphoribosyltransferase;
DE              Short=OPRT;
DE              Short=OPRTase;
DE              EC=2.4.2.10;
DE   Includes:
DE     RecName: Full=Orotidine 5'-phosphate decarboxylase;
DE              Short=ODC;
DE              EC=4.1.1.23;
DE     AltName: Full=OMPdecase;
GN   Name=UMPS; ORFNames=OK/SW-cl.21;
DR   GO; GO:0004588; F:orotate phosphoribosyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IDA:UniProtKB.
DR   GO; GO:0006207; P:'de novo' pyrimidine nucleobase biosynthetic process; IEA:InterPro.
DR   GO; GO:0044205; P:'de novo' UMP biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0006222; P:UMP biosynthetic process; IDA:UniProtKB.
//
ID   UN13A_HUMAN             Reviewed;        1703 AA.
AC   Q9UPW8; E5RHY9;
DE   RecName: Full=Protein unc-13 homolog A;
DE   AltName: Full=Munc13-1;
GN   Name=UNC13A; Synonyms=KIAA1032;
DR   GO; GO:0019992; F:diacylglycerol binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0050435; P:beta-amyloid metabolic process; IEA:Ensembl.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0001956; P:positive regulation of neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0016081; P:synaptic vesicle docking involved in exocytosis; IEA:Ensembl.
DR   GO; GO:0016188; P:synaptic vesicle maturation; IEA:Ensembl.
//
ID   UN13B_HUMAN             Reviewed;        1591 AA.
AC   O14795; Q5VYM8;
DE   RecName: Full=Protein unc-13 homolog B;
DE   AltName: Full=Munc13-2;
DE            Short=munc13;
GN   Name=UNC13B; Synonyms=UNC13;
DR   GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004871; F:signal transducer activity; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0060384; P:innervation; IEA:Ensembl.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007528; P:neuromuscular junction development; IEA:Ensembl.
DR   GO; GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0016081; P:synaptic vesicle docking involved in exocytosis; IEA:Ensembl.
DR   GO; GO:0016082; P:synaptic vesicle priming; IEA:Ensembl.
//
ID   UN13C_HUMAN             Reviewed;        2214 AA.
AC   Q8NB66; Q0P613; Q8ND48; Q96NP3;
DE   RecName: Full=Protein unc-13 homolog C;
DE   AltName: Full=Munc13-3;
GN   Name=UNC13C;
DR   GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0007268; P:synaptic transmission; IEA:Ensembl.
//
ID   UN13D_HUMAN             Reviewed;        1090 AA.
AC   Q70J99; B4DWG9; Q9H7K5;
DE   RecName: Full=Protein unc-13 homolog D;
DE   AltName: Full=Munc13-4;
GN   Name=UNC13D;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:0002467; P:germinal center formation; IEA:Ensembl.
DR   GO; GO:0002432; P:granuloma formation; IEA:Ensembl.
DR   GO; GO:0043320; P:natural killer cell degranulation; IEA:Ensembl.
DR   GO; GO:0006909; P:phagocytosis; IEA:Ensembl.
DR   GO; GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.
DR   GO; GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.
//
ID   UN45A_HUMAN             Reviewed;         944 AA.
AC   Q9H3U1; A8K6F7; Q7L3Y6; Q9H3U8; Q9NSE8; Q9NSE9;
DE   RecName: Full=Protein unc-45 homolog A;
DE            Short=Unc-45A;
DE   AltName: Full=GCUNC-45;
DE   AltName: Full=Smooth muscle cell-associated protein 1;
DE            Short=SMAP-1;
GN   Name=UNC45A; Synonyms=SMAP1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
//
ID   UN45B_HUMAN             Reviewed;         931 AA.
AC   Q8IWX7; Q495Q8; Q495Q9;
DE   RecName: Full=Protein unc-45 homolog B;
DE            Short=Unc-45B;
DE   AltName: Full=SMUNC45;
GN   Name=UNC45B; Synonyms=CMYA4, UNC45;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0061077; P:chaperone-mediated protein folding; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
//
ID   UN5CL_HUMAN             Reviewed;         518 AA.
AC   Q8IV45; Q5TGU1;
DE   RecName: Full=UNC5C-like protein;
DE   AltName: Full=Protein unc-5 homolog C-like;
DE   AltName: Full=ZU5 and death domain-containing protein;
GN   Name=UNC5CL; Synonyms=ZUD;
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   UN93A_HUMAN             Reviewed;         457 AA.
AC   Q86WB7; B3KRP5; Q4QQJ4; Q5JZD6;
DE   RecName: Full=Protein unc-93 homolog A;
DE            Short=HmUnc-93A;
DE            Short=Unc-93A;
GN   Name=UNC93A;
//
ID   UN93B_HUMAN             Reviewed;         597 AA.
AC   Q9H1C4; O95764; Q569H6; Q710D4;
DE   RecName: Full=Protein unc-93 homolog B1;
DE            Short=Unc-93B1;
DE            Short=hUNC93B1;
GN   Name=UNC93B1; Synonyms=UNC93, UNC93B;
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0034138; P:toll-like receptor 3 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034154; P:toll-like receptor 7 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0034162; P:toll-like receptor 9 signaling pathway; IMP:UniProtKB.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; TAS:Reactome.
//
ID   UNC4_HUMAN              Reviewed;         531 AA.
AC   A6NJT0; A4D221;
DE   RecName: Full=Homeobox protein unc-4 homolog;
DE   AltName: Full=Homeobox protein Uncx4.1;
GN   Name=UNCX; Synonyms=UNCX4.1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0001502; P:cartilage condensation; IEA:Ensembl.
DR   GO; GO:0035726; P:common myeloid progenitor cell proliferation; IEA:Ensembl.
DR   GO; GO:0021516; P:dorsal spinal cord development; IEA:Ensembl.
DR   GO; GO:0021889; P:olfactory bulb interneuron differentiation; IEA:Ensembl.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0045595; P:regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   UNC50_HUMAN             Reviewed;         259 AA.
AC   Q53HI1; D3DVH4; Q53S98; Q53TD6; Q5U5U2; Q6X7B9; Q9UQF4; Q9Y4S6;
DE   RecName: Full=Protein unc-50 homolog;
DE   AltName: Full=Periodontal ligament-specific protein 22;
DE            Short=PDLs22;
DE   AltName: Full=Protein GMH1 homolog;
DE            Short=hGMH1;
DE   AltName: Full=Uncoordinated-like protein;
GN   Name=UNC50; Synonyms=UNCL; ORFNames=HSD-23, HSD23;
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   UNC5A_HUMAN             Reviewed;         842 AA.
AC   Q6ZN44; B2RXE6; Q8TF26; Q96GP4;
DE   RecName: Full=Netrin receptor UNC5A;
DE   AltName: Full=Protein unc-5 homolog 1;
DE   AltName: Full=Protein unc-5 homolog A;
DE   Flags: Precursor;
GN   Name=UNC5A; Synonyms=KIAA1976, UNC5H1;
DR   GO; GO:0033564; P:anterior/posterior axon guidance; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   UNC5B_HUMAN             Reviewed;         945 AA.
AC   Q8IZJ1; Q5T3R9; Q5T3S0; Q86SN3; Q8N1Y2; Q9H9F3;
DE   RecName: Full=Netrin receptor UNC5B;
DE   AltName: Full=Protein unc-5 homolog 2;
DE   AltName: Full=Protein unc-5 homolog B;
DE   AltName: Full=p53-regulated receptor for death and life protein 1;
DE   Flags: Precursor;
GN   Name=UNC5B; Synonyms=P53RDL1, UNC5H2; ORFNames=UNQ1883/PRO4326;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0033564; P:anterior/posterior axon guidance; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   UNC5C_HUMAN             Reviewed;         931 AA.
AC   O95185; Q8IUT0;
DE   RecName: Full=Netrin receptor UNC5C;
DE   AltName: Full=Protein unc-5 homolog 3;
DE   AltName: Full=Protein unc-5 homolog C;
DE   Flags: Precursor;
GN   Name=UNC5C; Synonyms=UNC5H3;
DR   GO; GO:0005042; F:netrin receptor activity; TAS:ProtInc.
DR   GO; GO:0033564; P:anterior/posterior axon guidance; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
//
ID   UNC5D_HUMAN             Reviewed;         953 AA.
AC   Q6UXZ4; Q8WYP7;
DE   RecName: Full=Netrin receptor UNC5D;
DE   AltName: Full=Protein unc-5 homolog 4;
DE   AltName: Full=Protein unc-5 homolog D;
DE   Flags: Precursor;
GN   Name=UNC5D; Synonyms=KIAA1777, UNC5H4; ORFNames=UNQ6012/PRO34692;
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0021859; P:pyramidal neuron differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
//
ID   UNC79_HUMAN             Reviewed;        2635 AA.
AC   Q9P2D8; B5MDL6; Q6ZUT7;
DE   RecName: Full=Protein unc-79 homolog;
GN   Name=UNC79; Synonyms=KIAA1409;
DR   GO; GO:0048149; P:behavioral response to ethanol; IEA:Ensembl.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   UNC80_HUMAN             Reviewed;        3258 AA.
AC   Q8N2C7; B2RN50; B4DQY9; B4DZB3; C4IXS8; C9J1U3; Q96JI4; Q96SS0;
DE   RecName: Full=Protein unc-80 homolog;
GN   Name=UNC80; Synonyms=C2orf21, KIAA1843;
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   UNG_HUMAN               Reviewed;         313 AA.
AC   P13051; A8K5M6; B2R8Y1; O00637; O00719; Q93028;
DE   RecName: Full=Uracil-DNA glycosylase;
DE            Short=UDG;
DE            EC=3.2.2.27;
GN   Name=UNG; Synonyms=DGU, UNG1, UNG15;
DR   GO; GO:0004844; F:uracil DNA N-glycosylase activity; NAS:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0016446; P:somatic hypermutation of immunoglobulin genes; IEA:Ensembl.
DR   GO; GO:0016447; P:somatic recombination of immunoglobulin gene segments; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   UNKL_HUMAN              Reviewed;         680 AA.
AC   Q9H9P5; B0QYN6; B1GXI8; Q96EV1; Q96RZ1; Q9BWL5; Q9H5K0; Q9UJJ8;
DE   RecName: Full=Putative E3 ubiquitin-protein ligase UNKL;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein unkempt-like;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 5-like;
GN   Name=UNKL; Synonyms=C16orf28, ZC3H5L, ZC3HDC5L;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   UNK_HUMAN               Reviewed;         810 AA.
AC   Q9C0B0;
DE   RecName: Full=RING finger protein unkempt homolog;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 5;
GN   Name=UNK; Synonyms=KIAA1753, ZC3H5, ZC3HDC5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   UPAR_HUMAN              Reviewed;         335 AA.
AC   Q03405; A8K409; Q12876; Q15845; Q16887; Q6IB52; Q9BWT0; Q9NYC8;
AC   Q9UD69; Q9UEA6; Q9UM92; Q9UMV0;
DE   RecName: Full=Urokinase plasminogen activator surface receptor;
DE            Short=U-PAR;
DE            Short=uPAR;
DE   AltName: Full=Monocyte activation antigen Mo3;
DE   AltName: CD_antigen=CD87;
DE   Flags: Precursor;
GN   Name=PLAUR; Synonyms=MO3, UPAR;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0030377; F:urokinase plasminogen activator receptor activity; NAS:UniProtKB.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; NAS:UniProtKB.
DR   GO; GO:0006501; P:C-terminal protein lipidation; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; NAS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0030162; P:regulation of proteolysis; NAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0038195; P:urokinase plasminogen activator signaling pathway; NAS:GOC.
//
ID   UPK1A_HUMAN             Reviewed;         258 AA.
AC   O00322; Q3KNU5; Q3KNU6;
DE   RecName: Full=Uroplakin-1a;
DE            Short=UP1a;
DE   AltName: Full=Tetraspanin-21;
DE            Short=Tspan-21;
DE   AltName: Full=Uroplakin Ia;
DE            Short=UPIa;
DE            Short=UPKa;
GN   Name=UPK1A; Synonyms=TSPAN21;
DR   GO; GO:0048029; F:monosaccharide binding; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0051259; P:protein oligomerization; ISS:UniProtKB.
//
ID   UPK1B_HUMAN             Reviewed;         260 AA.
AC   O75841; O60753; Q9UIM2; Q9UNX6;
DE   RecName: Full=Uroplakin-1b;
DE            Short=UP1b;
DE   AltName: Full=Tetraspanin-20;
DE            Short=Tspan-20;
DE   AltName: Full=Uroplakin Ib;
DE            Short=UPIb;
GN   Name=UPK1B; Synonyms=TSPAN20;
DR   GO; GO:0005198; F:structural molecule activity; NAS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProtKB.
//
ID   UPK2_HUMAN              Reviewed;         184 AA.
AC   O00526; B0YJ92; O00457; Q53YV0;
DE   RecName: Full=Uroplakin-2;
DE            Short=UP2;
DE   AltName: Full=Uroplakin II;
DE            Short=UPII;
DE   Flags: Precursor;
GN   Name=UPK2;
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
//
ID   UPK3A_HUMAN             Reviewed;         287 AA.
AC   O75631; B0QY25; O60261; Q32N05; Q5TII6;
DE   RecName: Full=Uroplakin-3a;
DE            Short=UP3a;
DE   AltName: Full=Uroplakin III;
DE            Short=UPIII;
DE   Flags: Precursor;
GN   Name=UPK3A; Synonyms=UPK3;
DR   GO; GO:0000902; P:cell morphogenesis; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0055075; P:potassium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0055078; P:sodium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0015840; P:urea transport; IEA:Ensembl.
DR   GO; GO:0060157; P:urinary bladder development; IEA:Ensembl.
DR   GO; GO:0006833; P:water transport; IEA:Ensembl.
//
ID   UPK3B_HUMAN             Reviewed;         320 AA.
AC   Q9BT76; A6NHH5; A8K231; A8MZA8; B3KPU5; Q75MM5; Q86W06;
DE   RecName: Full=Uroplakin-3b;
DE            Short=UP3b;
DE   AltName: Full=Uroplakin IIIb;
DE            Short=UPIIIb;
DE   AltName: Full=p35;
DE   Flags: Precursor;
GN   Name=UPK3B;
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
//
ID   UPK3L_HUMAN             Reviewed;         263 AA.
AC   B0FP48;
DE   RecName: Full=Uroplakin-3b-like protein;
DE   Flags: Precursor;
GN   Name=UPK3BL; Synonyms=UPLP;
//
ID   UPP1_HUMAN              Reviewed;         310 AA.
AC   Q16831; D3DVM4; Q15362;
DE   RecName: Full=Uridine phosphorylase 1;
DE            Short=UPase 1;
DE            Short=UrdPase 1;
DE            EC=2.4.2.3;
GN   Name=UPP1; Synonyms=UP;
DR   GO; GO:0004850; F:uridine phosphorylase activity; TAS:ProtInc.
DR   GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046108; P:uridine metabolic process; IEA:Ensembl.
//
ID   UPP2_HUMAN              Reviewed;         317 AA.
AC   O95045; B3KV87;
DE   RecName: Full=Uridine phosphorylase 2;
DE            Short=UPase 2;
DE            Short=UrdPase 2;
DE            EC=2.4.2.3;
GN   Name=UPP2;
DR   GO; GO:0004850; F:uridine phosphorylase activity; IDA:UniProtKB.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009116; P:nucleoside metabolic process; NAS:UniProtKB.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   GO; GO:0006206; P:pyrimidine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0046135; P:pyrimidine nucleoside catabolic process; TAS:Reactome.
DR   GO; GO:0043097; P:pyrimidine nucleoside salvage; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0044206; P:UMP salvage; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046108; P:uridine metabolic process; NAS:UniProtKB.
//
ID   UPP_HUMAN               Reviewed;         309 AA.
AC   Q96BW1; Q5JRL1; Q5JRL3; Q68DN0; Q96MW2;
DE   RecName: Full=Uracil phosphoribosyltransferase homolog;
GN   Name=UPRT;
DR   GO; GO:0007565; P:female pregnancy; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0006222; P:UMP biosynthetic process; IEA:Ensembl.
//
ID   UQCC1_HUMAN             Reviewed;         299 AA.
AC   Q9NVA1; B1AKV5; Q0VF37; Q5T348; Q5T351; Q5T353; Q86YU3; Q86YU4;
AC   Q96H66; Q9H438; Q9H452; Q9H9K8; Q9H9R5;
DE   RecName: Full=Ubiquinol-cytochrome-c reductase complex assembly factor 1;
DE   AltName: Full=Basic FGF-repressed Zic-binding protein;
DE            Short=bFGF-repressed Zic-binding protein;
DE            Short=bFZb;
DE   AltName: Full=Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog;
GN   Name=UQCC1; Synonyms=BZFB, C20orf44, UQCC;
//
ID   UQCC2_HUMAN             Reviewed;         126 AA.
AC   Q9BRT2; B2R4I0;
DE   RecName: Full=Ubiquinol-cytochrome-c reductase complex assembly factor 2;
DE   AltName: Full=Breast cancer-associated protein SGA-81M;
DE   AltName: Full=Mitochondrial nucleoid factor 1;
DE   AltName: Full=Mitochondrial protein M19;
DE   Flags: Precursor;
GN   Name=UQCC2; Synonyms=C6orf125, MNF1;
DR   GO; GO:0050796; P:regulation of insulin secretion; ISS:UniProtKB.
DR   GO; GO:0002082; P:regulation of oxidative phosphorylation; IMP:UniProtKB.
DR   GO; GO:2001014; P:regulation of skeletal muscle cell differentiation; ISS:UniProtKB.
//
ID   UR2R_HUMAN              Reviewed;         389 AA.
AC   Q9UKP6; B2RMV8;
DE   RecName: Full=Urotensin-2 receptor;
DE            Short=UR-2-R;
DE   AltName: Full=G-protein coupled receptor 14;
DE   AltName: Full=Urotensin II receptor;
DE            Short=UR-II-R;
GN   Name=UTS2R; Synonyms=GPR14;
DR   GuidetoPHARMACOLOGY; 365; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0001604; F:urotensin II receptor activity; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0003105; P:negative regulation of glomerular filtration; IEA:Ensembl.
DR   GO; GO:0035814; P:negative regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0035811; P:negative regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0046005; P:positive regulation of circadian sleep/wake cycle, REM sleep; IEA:Ensembl.
DR   GO; GO:0010841; P:positive regulation of circadian sleep/wake cycle, wakefulness; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0042312; P:regulation of vasodilation; IEA:InterPro.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   URAD_HUMAN              Reviewed;         173 AA.
AC   A6NGE7;
DE   RecName: Full=Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase;
DE            Short=OHCU decarboxylase;
DE            EC=4.1.1.97;
DE   AltName: Full=Parahox neighbor;
DE   AltName: Full=Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase;
GN   Name=URAD; Synonyms=PRHOXNB;
DR   GO; GO:0016831; F:carboxy-lyase activity; ISS:UniProtKB.
DR   GO; GO:0019428; P:allantoin biosynthetic process; IEA:InterPro.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0019628; P:urate catabolic process; IEA:UniProtKB-UniPathway.
//
ID   URB2_HUMAN              Reviewed;        1524 AA.
AC   Q14146; Q5VYC9;
DE   RecName: Full=Unhealthy ribosome biogenesis protein 2 homolog;
GN   Name=URB2; Synonyms=KIAA0133;
//
ID   URFB1_HUMAN             Reviewed;        1440 AA.
AC   Q6BDS2; Q9NXE0;
DE   RecName: Full=UHRF1-binding protein 1;
DE   AltName: Full=ICBP90-binding protein 1;
DE   AltName: Full=Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1;
GN   Name=UHRF1BP1; Synonyms=C6orf107;
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0042802; F:identical protein binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
//
ID   URGCP_HUMAN             Reviewed;         931 AA.
AC   Q8TCY9; E9PFF6; Q658M4; Q68DH6; Q6MZZ5; Q8WV98; Q9NWR7; Q9P221;
DE   RecName: Full=Up-regulator of cell proliferation;
DE   AltName: Full=HBV X protein up-regulated gene 4 protein;
DE   AltName: Full=HBxAg up-regulated gene 4 protein;
GN   Name=URGCP; Synonyms=KIAA1507, URG4;
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
//
ID   URM1_HUMAN              Reviewed;         101 AA.
AC   Q9BTM9; B3KMH3; B4DV08; Q5T4B4;
DE   RecName: Full=Ubiquitin-related modifier 1;
GN   Name=URM1; Synonyms=C9orf74;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032447; P:protein urmylation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0034227; P:tRNA thio-modification; IMP:UniProtKB.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IMP:UniProtKB.
//
ID   UROK_HUMAN              Reviewed;         431 AA.
AC   P00749; B4DPZ2; Q15844; Q16618; Q53XS3; Q5SWW9; Q969W6;
DE   RecName: Full=Urokinase-type plasminogen activator;
DE            Short=U-plasminogen activator;
DE            Short=uPA;
DE            EC=3.4.21.73;
DE   Contains:
DE     RecName: Full=Urokinase-type plasminogen activator long chain A;
DE   Contains:
DE     RecName: Full=Urokinase-type plasminogen activator short chain A;
DE   Contains:
DE     RecName: Full=Urokinase-type plasminogen activator chain B;
DE   Flags: Precursor;
GN   Name=PLAU;
DR   GuidetoPHARMACOLOGY; 2393; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0042730; P:fibrinolysis; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0033628; P:regulation of cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:0042127; P:regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010469; P:regulation of receptor activity; IDA:BHF-UCL.
DR   GO; GO:0014910; P:regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:2000097; P:regulation of smooth muscle cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0061041; P:regulation of wound healing; IC:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0014909; P:smooth muscle cell migration; IEA:Ensembl.
//
ID   UROL1_HUMAN             Reviewed;        1318 AA.
AC   Q5DID0; C9JCE6; Q5DIC9; Q6LA40; Q6LA41; Q8N216;
DE   RecName: Full=Uromodulin-like 1;
DE   AltName: Full=Olfactorin;
DE   Flags: Precursor;
GN   Name=UMODL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
//
ID   UROM_HUMAN              Reviewed;         640 AA.
AC   P07911; B3KP48; B3KRN9; E9PEA4; Q540J6; Q6ZS84; Q8IYG0;
DE   RecName: Full=Uromodulin;
DE   AltName: Full=Tamm-Horsfall urinary glycoprotein;
DE            Short=THP;
DE   Contains:
DE     RecName: Full=Uromodulin, secreted form;
DE   Flags: Precursor;
GN   Name=UMOD;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0019864; F:IgG binding; IDA:BHF-UCL.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0048878; P:chemical homeostasis; IEA:Ensembl.
DR   GO; GO:0007588; P:excretion; IEA:Ensembl.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0072218; P:metanephric ascending thin limb development; IEA:Ensembl.
DR   GO; GO:0072221; P:metanephric distal convoluted tubule development; IEA:Ensembl.
DR   GO; GO:0072233; P:metanephric thick ascending limb development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:1990266; P:neutrophil migration; IDA:BHF-UCL.
DR   GO; GO:2000021; P:regulation of ion homeostasis; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
//
ID   URP2_HUMAN              Reviewed;         667 AA.
AC   Q86UX7; Q8IUA1; Q8N207; Q9BT48;
DE   RecName: Full=Fermitin family homolog 3;
DE   AltName: Full=Kindlin-3;
DE   AltName: Full=MIG2-like protein;
DE   AltName: Full=Unc-112-related protein 2;
GN   Name=FERMT3; Synonyms=KIND3, MIG2B, URP2;
DR   GO; GO:0005178; F:integrin binding; ISS:UniProtKB.
DR   GO; GO:0033622; P:integrin activation; IMP:UniProtKB.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0070527; P:platelet aggregation; ISS:UniProtKB.
DR   GO; GO:0033632; P:regulation of cell-cell adhesion mediated by integrin; IMP:UniProtKB.
//
ID   US6NL_HUMAN             Reviewed;         828 AA.
AC   Q92738; A8KA79; Q15400; Q5VV10; Q7L0K9;
DE   RecName: Full=USP6 N-terminal-like protein;
DE   AltName: Full=Related to the N-terminus of tre;
DE            Short=RN-tre;
GN   Name=USP6NL; Synonyms=KIAA0019;
DR   GO; GO:0005097; F:Rab GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0007030; P:Golgi organization; IMP:UniProtKB.
DR   GO; GO:0032851; P:positive regulation of Rab GTPase activity; IDA:GOC.
DR   GO; GO:0035526; P:retrograde transport, plasma membrane to Golgi; IMP:UniProtKB.
//
ID   USB1_HUMAN              Reviewed;         265 AA.
AC   Q9BQ65; B4DWE3; B4DZW5; Q96FZ9; Q9H8X8;
DE   RecName: Full=U6 snRNA phosphodiesterase;
DE            Short=hUsb1;
DE            EC=3.1.4.-;
GN   Name=USB1; Synonyms=C16orf57;
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; IDA:GOC.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
DR   GO; GO:0034477; P:U6 snRNA 3'-end processing; IMP:UniProtKB.
//
ID   USBP1_HUMAN             Reviewed;         703 AA.
AC   Q8N6Y0; A8K7L6; B2RCR9; Q8NBX7; Q96KH3; Q9BYI8;
DE   RecName: Full=Usher syndrome type-1C protein-binding protein 1;
DE            Short=USH1C-binding protein 1;
DE   AltName: Full=AIE-75-binding protein;
DE   AltName: Full=MCC-2;
DE   AltName: Full=Mutated in colon cancer protein 2;
GN   Name=USHBP1; Synonyms=AIEBP, MCC2;
DR   GO; GO:0030165; F:PDZ domain binding; IPI:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   USE1_HUMAN              Reviewed;         259 AA.
AC   Q9NZ43; Q8NCK1; Q9BRT4;
DE   RecName: Full=Vesicle transport protein USE1;
DE   AltName: Full=Putative MAPK-activating protein PM26;
DE   AltName: Full=USE1-like protein;
DE   AltName: Full=p31;
GN   Name=USE1; Synonyms=USE1L; ORFNames=MDS032;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0071786; P:endoplasmic reticulum tubular network organization; IEA:Ensembl.
DR   GO; GO:0007041; P:lysosomal transport; ISS:HGNC.
DR   GO; GO:0030163; P:protein catabolic process; ISS:HGNC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0032940; P:secretion by cell; ISS:HGNC.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   USF2_HUMAN              Reviewed;         346 AA.
AC   Q15853; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q6FI33;
AC   Q6YI47;
DE   RecName: Full=Upstream stimulatory factor 2;
DE   AltName: Full=Class B basic helix-loop-helix protein 12;
DE            Short=bHLHb12;
DE   AltName: Full=FOS-interacting protein;
DE            Short=FIP;
DE   AltName: Full=Major late transcription factor 2;
DE   AltName: Full=Upstream transcription factor 2;
GN   Name=USF2; Synonyms=BHLHB12;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0019086; P:late viral transcription; IC:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.
DR   GO; GO:0000430; P:regulation of transcription from RNA polymerase II promoter by glucose; IC:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IMP:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   USF1_HUMAN              Reviewed;         310 AA.
AC   P22415; B2RBZ4; Q5SY46; Q7Z5Y1;
DE   RecName: Full=Upstream stimulatory factor 1;
DE   AltName: Full=Class B basic helix-loop-helix protein 11;
DE            Short=bHLHb11;
DE   AltName: Full=Major late transcription factor 1;
GN   Name=USF1; Synonyms=BHLHB11, USF;
DR   GO; GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:BHF-UCL.
DR   GO; GO:0045990; P:carbon catabolite regulation of transcription; TAS:BHF-UCL.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; TAS:BHF-UCL.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0019086; P:late viral transcription; IDA:BHF-UCL.
DR   GO; GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IC:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0000432; P:positive regulation of transcription from RNA polymerase II promoter by glucose; IMP:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.
DR   GO; GO:0000430; P:regulation of transcription from RNA polymerase II promoter by glucose; IC:BHF-UCL.
DR   GO; GO:0001666; P:response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0009411; P:response to UV; ISS:BHF-UCL.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
//
ID   USH1C_HUMAN             Reviewed;         552 AA.
AC   Q9Y6N9; A8K423; Q7RTU8; Q96B29; Q9UM04; Q9UM17; Q9UPC3;
DE   RecName: Full=Harmonin;
DE   AltName: Full=Antigen NY-CO-38/NY-CO-37;
DE   AltName: Full=Autoimmune enteropathy-related antigen AIE-75;
DE   AltName: Full=Protein PDZ-73;
DE   AltName: Full=Renal carcinoma antigen NY-REN-3;
DE   AltName: Full=Usher syndrome type-1C protein;
GN   Name=USH1C; Synonyms=AIE75;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0042491; P:auditory receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0050957; P:equilibrioception; IMP:HGNC.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:HGNC.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0030046; P:parallel actin filament bundle assembly; IEA:Ensembl.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
//
ID   USH1G_HUMAN             Reviewed;         461 AA.
AC   Q495M9; Q8N251;
DE   RecName: Full=Usher syndrome type-1G protein;
DE   AltName: Full=Scaffold protein containing ankyrin repeats and SAM domain;
GN   Name=USH1G; Synonyms=SANS;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030507; F:spectrin binding; IDA:MGI.
DR   GO; GO:0050957; P:equilibrioception; IMP:HGNC.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0060113; P:inner ear receptor cell differentiation; IEA:Ensembl.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
//
ID   USH2A_HUMAN             Reviewed;        5202 AA.
AC   O75445; Q5VVM9; Q6S362; Q9NS27;
DE   RecName: Full=Usherin;
DE   AltName: Full=Usher syndrome type IIa protein;
DE   AltName: Full=Usher syndrome type-2A protein;
DE   Flags: Precursor;
GN   Name=USH2A;
DR   GO; GO:0005518; F:collagen binding; IDA:HGNC.
DR   GO; GO:0017022; F:myosin binding; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0035315; P:hair cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0060113; P:inner ear receptor cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0048496; P:maintenance of organ identity; IMP:HGNC.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IMP:HGNC.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   USMG5_HUMAN             Reviewed;          58 AA.
AC   Q96IX5; B2R4N2; D3DR92;
DE   RecName: Full=Up-regulated during skeletal muscle growth protein 5;
DE   AltName: Full=Diabetes-associated protein in insulin-sensitive tissues;
DE   AltName: Full=HCV F-transactivated protein 2;
GN   Name=USMG5; Synonyms=DAPIT, HCVFTP2; ORFNames=PD04912;
//
ID   USO1_HUMAN              Reviewed;         962 AA.
AC   O60763; B2RAQ0; Q6PK63; Q86TB8; Q8N592;
DE   RecName: Full=General vesicular transport factor p115;
DE   AltName: Full=Protein USO1 homolog;
DE   AltName: Full=Transcytosis-associated protein;
DE            Short=TAP;
DE   AltName: Full=Vesicle-docking protein;
GN   Name=USO1; Synonyms=VDP;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IBA:RefGenome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IBA:RefGenome.
DR   GO; GO:0048211; P:Golgi vesicle docking; IBA:RefGenome.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:RefGenome.
DR   GO; GO:0061025; P:membrane fusion; IBA:RefGenome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0045056; P:transcytosis; IBA:RefGenome.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:InterPro.
//
ID   USP9X_HUMAN             Reviewed;        2570 AA.
AC   Q93008; O75550; Q8WWT3; Q8WX12;
DE   RecName: Full=Probable ubiquitin carboxyl-terminal hydrolase FAF-X;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme FAF-X;
DE   AltName: Full=Fat facets in mammals;
DE            Short=hFAM;
DE   AltName: Full=Fat facets protein-related, X-linked;
DE   AltName: Full=Ubiquitin thioesterase FAF-X;
DE   AltName: Full=Ubiquitin-specific protease 9, X chromosome;
DE   AltName: Full=Ubiquitin-specific-processing protease FAF-X;
GN   Name=USP9X; Synonyms=DFFRX, FAM, USP9;
DR   GO; GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; TAS:Reactome.
DR   GO; GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0007292; P:female gamete generation; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   USP9Y_HUMAN             Reviewed;        2555 AA.
AC   O00507; O14601;
DE   RecName: Full=Probable ubiquitin carboxyl-terminal hydrolase FAF-Y;
DE            EC=3.4.19.12;
DE   AltName: Full=Deubiquitinating enzyme FAF-Y;
DE   AltName: Full=Fat facets protein-related, Y-linked;
DE   AltName: Full=Ubiquitin thioesterase FAF-Y;
DE   AltName: Full=Ubiquitin-specific protease 9, Y chromosome;
DE   AltName: Full=Ubiquitin-specific-processing protease FAF-Y;
GN   Name=USP9Y; Synonyms=DFFRY;
DR   GO; GO:0070410; F:co-SMAD binding; ISS:BHF-UCL.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; TAS:ProtInc.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; TAS:ProtInc.
DR   GO; GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
//
ID   USPL1_HUMAN             Reviewed;        1092 AA.
AC   Q5W0Q7; Q14109; Q6AI45; Q8IY30; Q8IYE8;
DE   RecName: Full=SUMO-specific isopeptidase USPL1;
DE            EC=3.4.22.-;
DE   AltName: Full=Ubiquitin-specific peptidase-like protein 1;
GN   Name=USPL1; Synonyms=C13orf22, D13S106;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032183; F:SUMO binding; IDA:UniProtKB.
DR   GO; GO:0070140; F:SUMO-specific isopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0030576; P:Cajal body organization; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0016926; P:protein desumoylation; IDA:UniProtKB.
//
ID   UST_HUMAN               Reviewed;         406 AA.
AC   Q9Y2C2; B2RCX6;
DE   RecName: Full=Uronyl 2-sulfotransferase;
DE            EC=2.8.2.-;
GN   Name=UST; Synonyms=DS2ST;
DR   GO; GO:0008146; F:sulfotransferase activity; TAS:ProtInc.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:Reactome.
DR   GO; GO:0030204; P:chondroitin sulfate metabolic process; TAS:Reactome.
DR   GO; GO:0030208; P:dermatan sulfate biosynthetic process; TAS:Reactome.
DR   GO; GO:0030203; P:glycosaminoglycan metabolic process; TAS:Reactome.
DR   GO; GO:0006477; P:protein sulfation; TAS:ProtInc.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   UT14A_HUMAN             Reviewed;         771 AA.
AC   Q9BVJ6; A8K7A3; A8MVQ1; B4DQ08; E9PEL7; Q5JYF1;
DE   RecName: Full=U3 small nucleolar RNA-associated protein 14 homolog A;
DE   AltName: Full=Antigen NY-CO-16;
DE   AltName: Full=Serologically defined colon cancer antigen 16;
GN   Name=UTP14A; Synonyms=SDCCAG16;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
//
ID   UT1_HUMAN               Reviewed;         389 AA.
AC   Q13336; A8K0P3; B3KR62; B3KVX3; C9EHF2; Q86VM5;
DE   RecName: Full=Urea transporter 1;
DE   AltName: Full=Solute carrier family 14 member 1;
DE   AltName: Full=Urea transporter, erythrocyte;
GN   Name=SLC14A1; Synonyms=HUT11, JK, RACH1, UT1, UTE;
DR   GO; GO:0015204; F:urea transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0005372; F:water transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015840; P:urea transport; TAS:ProtInc.
//
ID   UT14C_HUMAN             Reviewed;         766 AA.
AC   Q5TAP6; Q5FWG3; Q92555;
DE   RecName: Full=U3 small nucleolar RNA-associated protein 14 homolog C;
GN   Name=UTP14C; Synonyms=KIAA0266;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   UT2_HUMAN               Reviewed;         920 AA.
AC   Q15849; A8K8Q7; Q2TBD6; Q96PH5;
DE   RecName: Full=Urea transporter 2;
DE   AltName: Full=Solute carrier family 14 member 2;
DE   AltName: Full=Urea transporter, kidney;
GN   Name=SLC14A2; Synonyms=HUT2, UT2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015204; F:urea transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0015840; P:urea transport; TAS:ProtInc.
//
ID   UTER_HUMAN              Reviewed;          91 AA.
AC   P11684; B2R5F2; Q6FHH3; Q9UCM2; Q9UCM4;
DE   RecName: Full=Uteroglobin;
DE   AltName: Full=Clara cell phospholipid-binding protein;
DE            Short=CCPBP;
DE   AltName: Full=Clara cells 10 kDa secretory protein;
DE            Short=CC10;
DE   AltName: Full=Secretoglobin family 1A member 1;
DE   AltName: Full=Urinary protein 1;
DE            Short=UP-1;
DE            Short=UP1;
DE            Short=Urine protein 1;
DE   Flags: Precursor;
GN   Name=SCGB1A1; Synonyms=CC10, CCSP, UGB;
DR   GO; GO:0019834; F:phospholipase A2 inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007566; P:embryo implantation; TAS:ProtInc.
DR   GO; GO:0007565; P:female pregnancy; NAS:ProtInc.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0032696; P:negative regulation of interleukin-13 production; IEA:Ensembl.
DR   GO; GO:0032713; P:negative regulation of interleukin-4 production; IEA:Ensembl.
DR   GO; GO:0032714; P:negative regulation of interleukin-5 production; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0071774; P:response to fibroblast growth factor; IEA:Ensembl.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0010193; P:response to ozone; IEA:Ensembl.
DR   GO; GO:0034021; P:response to silicon dioxide; IEA:Ensembl.
DR   GO; GO:0009410; P:response to xenobiotic stimulus; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
//
ID   UTF1_HUMAN              Reviewed;         341 AA.
AC   Q5T230; O75833; Q6J1H3;
DE   RecName: Full=Undifferentiated embryonic cell transcription factor 1;
GN   Name=UTF1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   UTP11_HUMAN             Reviewed;         253 AA.
AC   Q9Y3A2; A8K785; D3DPT7; Q5VT93; Q9BS98; Q9NS31;
DE   RecName: Full=Probable U3 small nucleolar RNA-associated protein 11;
DE            Short=U3 snoRNA-associated protein 11;
DE   AltName: Full=UTP11-like protein;
GN   Name=UTP11L; ORFNames=CGI-94, HDCMB12P;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0007399; P:nervous system development; IMP:HGNC.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IBA:RefGenome.
DR   GO; GO:0006364; P:rRNA processing; IBA:RefGenome.
//
ID   UTP15_HUMAN             Reviewed;         518 AA.
AC   Q8TED0; Q6IA60; Q96E08; Q9H9F8;
DE   RecName: Full=U3 small nucleolar RNA-associated protein 15 homolog;
GN   Name=UTP15;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   UTP18_HUMAN             Reviewed;         556 AA.
AC   Q9Y5J1; Q9H4N6;
DE   RecName: Full=U3 small nucleolar RNA-associated protein 18 homolog;
DE   AltName: Full=WD repeat-containing protein 50;
GN   Name=UTP18; Synonyms=WDR50; ORFNames=CDABP0061, CGI-48;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   UTP20_HUMAN             Reviewed;        2785 AA.
AC   O75691; Q9H3H4;
DE   RecName: Full=Small subunit processome component 20 homolog;
DE   AltName: Full=Down-regulated in metastasis protein;
DE   AltName: Full=Novel nucleolar protein 73;
DE            Short=NNP73;
DE   AltName: Full=Protein Key-1A6;
GN   Name=UTP20; Synonyms=DRIM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0006364; P:rRNA processing; IMP:UniProtKB.
//
ID   UTP23_HUMAN             Reviewed;         249 AA.
AC   Q9BRU9; B2RE25; Q96NJ8;
DE   RecName: Full=rRNA-processing protein UTP23 homolog;
GN   Name=UTP23; Synonyms=C8orf53;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   UTP6_HUMAN              Reviewed;         597 AA.
AC   Q9NYH9; Q8IX96; Q96BL2; Q9NQ91;
DE   RecName: Full=U3 small nucleolar RNA-associated protein 6 homolog;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 66;
DE   AltName: Full=Multiple hat domains protein;
GN   Name=UTP6; Synonyms=C17orf40, HCA66, MHAT;
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   UTRO_HUMAN              Reviewed;        3433 AA.
AC   P46939; Q5SYY1; Q5SZ57; Q9UJ40;
DE   RecName: Full=Utrophin;
DE   AltName: Full=Dystrophin-related protein 1;
DE            Short=DRP-1;
GN   Name=UTRN; Synonyms=DMDL, DRP1;
DR   GO; GO:0003779; F:actin binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
DR   GO; GO:0017166; F:vinculin binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:UniProtKB.
DR   GO; GO:2000649; P:regulation of sodium ion transmembrane transporter activity; ISS:BHF-UCL.
//
ID   UTS2B_HUMAN             Reviewed;         119 AA.
AC   Q765I0; B3KQY8; D3DNW1; Q2M1Z2;
DE   RecName: Full=Urotensin-2B;
DE   AltName: Full=Urotensin II-related peptide;
DE   AltName: Full=Urotensin IIB;
DE            Short=U-IIB;
DE            Short=UIIB;
DE   AltName: Full=Urotensin-2 domain-containing protein;
DE   Flags: Precursor;
GN   Name=UTS2B; Synonyms=URP, UTS2D;
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0042312; P:regulation of vasodilation; IEA:InterPro.
//
ID   UTS2_HUMAN              Reviewed;         124 AA.
AC   O95399; Q5H8X7; Q6UXF6; Q9UKP7;
DE   RecName: Full=Urotensin-2;
DE   AltName: Full=Urotensin II;
DE            Short=U-II;
DE            Short=UII;
DE   Flags: Precursor;
GN   Name=UTS2; ORFNames=UNQ525/PRO1068;
DR   GO; GO:0005179; F:hormone activity; TAS:ProtInc.
DR   GO; GO:0005102; F:receptor binding; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0003105; P:negative regulation of glomerular filtration; IEA:Ensembl.
DR   GO; GO:0010459; P:negative regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0046676; P:negative regulation of insulin secretion; IEA:Ensembl.
DR   GO; GO:0035814; P:negative regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0035811; P:negative regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0045777; P:positive regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0046005; P:positive regulation of circadian sleep/wake cycle, REM sleep; IEA:Ensembl.
DR   GO; GO:0010841; P:positive regulation of circadian sleep/wake cycle, wakefulness; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0010763; P:positive regulation of fibroblast migration; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0032224; P:positive regulation of synaptic transmission, cholinergic; IEA:Ensembl.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0008217; P:regulation of blood pressure; TAS:ProtInc.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0033574; P:response to testosterone; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   UTY_HUMAN               Reviewed;        1347 AA.
AC   O14607; A8K9Z3; E1U199; E1U1A0; F5H4V7; F8W8R7; O14608;
DE   RecName: Full=Histone demethylase UTY;
DE            EC=1.14.11.-;
DE   AltName: Full=Ubiquitously-transcribed TPR protein on the Y chromosome;
DE   AltName: Full=Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein;
GN   Name=UTY;
DR   GO; GO:0051864; F:histone demethylase activity (H3-K36 specific); IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0086003; P:cardiac muscle cell contraction; IEA:Ensembl.
DR   GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0031935; P:regulation of chromatin silencing; IEA:Ensembl.
//
ID   UVRAG_HUMAN             Reviewed;         699 AA.
AC   Q9P2Y5; O00392;
DE   RecName: Full=UV radiation resistance-associated gene protein;
DE   AltName: Full=p63;
GN   Name=UVRAG;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:ProtInc.
DR   GO; GO:0010508; P:positive regulation of autophagy; IEA:InterPro.
//
ID   UVSSA_HUMAN             Reviewed;         709 AA.
AC   Q2YD98; A8K9E6; B2RU11; Q8WTX4; Q9P1Z8;
DE   RecName: Full=UV-stimulated scaffold protein A;
GN   Name=UVSSA; Synonyms=KIAA1530;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IMP:UniProtKB.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.
//
ID   UXS1_HUMAN              Reviewed;         420 AA.
AC   Q8NBZ7; Q8NBX3; Q9H5C2;
DE   RecName: Full=UDP-glucuronic acid decarboxylase 1;
DE            EC=4.1.1.35;
DE   AltName: Full=UDP-glucuronate decarboxylase 1;
DE            Short=UGD;
DE            Short=UXS-1;
GN   Name=UXS1; ORFNames=UNQ2538/PRO6079;
DR   GO; GO:0070403; F:NAD+ binding; IDA:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0048040; F:UDP-glucuronate decarboxylase activity; IDA:UniProt.
DR   GO; GO:0051262; P:protein tetramerization; IDA:UniProt.
DR   GO; GO:0033320; P:UDP-D-xylose biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   UXT_HUMAN               Reviewed;         157 AA.
AC   Q9UBK9; B2R561; Q5JZG3; Q9Y6E5;
DE   RecName: Full=Protein UXT;
DE   AltName: Full=Androgen receptor trapped clone 27 protein;
DE            Short=ART-27;
DE   AltName: Full=Ubiquitously expressed transcript protein;
GN   Name=UXT; ORFNames=HSPC024;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:HGNC.
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0008017; F:microtubule binding; TAS:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0051297; P:centrosome organization; IMP:HGNC.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IMP:HGNC.
DR   GO; GO:0047497; P:mitochondrion transport along microtubule; TAS:HGNC.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
//
ID   V1AR_HUMAN              Reviewed;         418 AA.
AC   P37288;
DE   RecName: Full=Vasopressin V1a receptor;
DE            Short=V1aR;
DE   AltName: Full=AVPR V1a;
DE   AltName: Full=Antidiuretic hormone receptor 1a;
DE   AltName: Full=Vascular/hepatic-type arginine vasopressin receptor;
GN   Name=AVPR1A; Synonyms=AVPR1;
DR   GuidetoPHARMACOLOGY; 366; -.
DR   GO; GO:0017046; F:peptide hormone binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005080; F:protein kinase C binding; TAS:ProtInc.
DR   GO; GO:0005000; F:vasopressin receptor activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0042631; P:cellular response to water deprivation; IEA:Ensembl.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0007625; P:grooming behavior; IEA:Ensembl.
DR   GO; GO:0002125; P:maternal aggressive behavior; IEA:Ensembl.
DR   GO; GO:0042711; P:maternal behavior; IEA:Ensembl.
DR   GO; GO:0014902; P:myotube differentiation; IEA:Ensembl.
DR   GO; GO:0007621; P:negative regulation of female receptivity; IEA:Ensembl.
DR   GO; GO:0051970; P:negative regulation of transmission of nerve impulse; IEA:Ensembl.
DR   GO; GO:0043084; P:penile erection; IEA:Ensembl.
DR   GO; GO:0030307; P:positive regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0032849; P:positive regulation of cellular pH reduction; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0014049; P:positive regulation of glutamate secretion; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IEA:Ensembl.
DR   GO; GO:0035815; P:positive regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0045907; P:positive regulation of vasoconstriction; IEA:Ensembl.
DR   GO; GO:0001992; P:regulation of systemic arterial blood pressure by vasopressin; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
DR   GO; GO:0042713; P:sperm ejaculation; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
//
ID   V1BR_HUMAN              Reviewed;         424 AA.
AC   P47901; B0M0J6; Q5TZ00;
DE   RecName: Full=Vasopressin V1b receptor;
DE            Short=V1bR;
DE   AltName: Full=AVPR V1b;
DE   AltName: Full=AVPR V3;
DE   AltName: Full=Antidiuretic hormone receptor 1b;
DE   AltName: Full=Vasopressin V3 receptor;
GN   Name=AVPR1B; Synonyms=AVPR3, VPR3;
DR   GuidetoPHARMACOLOGY; 367; -.
DR   GO; GO:0005080; F:protein kinase C binding; TAS:ProtInc.
DR   GO; GO:0005000; F:vasopressin receptor activity; TAS:ProtInc.
DR   GO; GO:0007202; P:activation of phospholipase C activity; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0001992; P:regulation of systemic arterial blood pressure by vasopressin; IEA:Ensembl.
//
ID   V2R_HUMAN               Reviewed;         371 AA.
AC   P30518; C5HF20; O43192; Q3MJD3; Q9UCV9;
DE   RecName: Full=Vasopressin V2 receptor;
DE            Short=V2R;
DE   AltName: Full=AVPR V2;
DE   AltName: Full=Antidiuretic hormone receptor;
DE   AltName: Full=Renal-type arginine vasopressin receptor;
GN   Name=AVPR2; Synonyms=ADHR, DIR, DIR3, V2R;
DR   GuidetoPHARMACOLOGY; 368; -.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0005000; F:vasopressin receptor activity; TAS:UniProtKB.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; TAS:ProtInc.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007588; P:excretion; TAS:ProtInc.
DR   GO; GO:0007599; P:hemostasis; TAS:ProtInc.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:Ensembl.
DR   GO; GO:0032609; P:interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0035814; P:negative regulation of renal sodium excretion; IEA:Ensembl.
DR   GO; GO:0035811; P:negative regulation of urine volume; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; NAS:BHF-UCL.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0034097; P:response to cytokine; IEA:Ensembl.
DR   GO; GO:0021537; P:telencephalon development; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006833; P:water transport; TAS:Reactome.
//
ID   VA0D1_HUMAN             Reviewed;         351 AA.
AC   P61421; P12953; Q02547;
DE   RecName: Full=V-type proton ATPase subunit d 1;
DE            Short=V-ATPase subunit d 1;
DE   AltName: Full=32 kDa accessory protein;
DE   AltName: Full=V-ATPase 40 kDa accessory protein;
DE   AltName: Full=V-ATPase AC39 subunit;
DE            Short=p39;
DE   AltName: Full=Vacuolar proton pump subunit d 1;
GN   Name=ATP6V0D1; Synonyms=ATP6D, VPATPD;
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0042384; P:cilium assembly; ISS:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; NAS:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VA0D2_HUMAN             Reviewed;         350 AA.
AC   Q8N8Y2;
DE   RecName: Full=V-type proton ATPase subunit d 2;
DE            Short=V-ATPase subunit d 2;
DE   AltName: Full=Vacuolar proton pump subunit d 2;
GN   Name=ATP6V0D2;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VA0E2_HUMAN             Reviewed;          81 AA.
AC   Q8NHE4; A2T863; A2T8L7; B5MDP5; J3KQW7; Q6MZW1; Q75L47; Q7Z4R7;
AC   Q8N7I8;
DE   RecName: Full=V-type proton ATPase subunit e 2;
DE            Short=V-ATPase subunit e 2;
DE   AltName: Full=Lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2;
DE   AltName: Full=Vacuolar proton pump subunit e 2;
GN   Name=ATP6V0E2; Synonyms=ATP6V0E2L, C7orf32;
DR   GO; GO:0042625; F:ATPase activity, coupled to transmembrane movement of ions; ISS:UniProtKB.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0016049; P:cell growth; IGI:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007035; P:vacuolar acidification; ISS:UniProtKB.
//
ID   VA0E1_HUMAN             Reviewed;          81 AA.
AC   O15342; B2R557; D3DQM1; Q6IBE8;
DE   RecName: Full=V-type proton ATPase subunit e 1;
DE            Short=V-ATPase subunit e 1;
DE   AltName: Full=V-ATPase 9.2 kDa membrane accessory protein;
DE   AltName: Full=V-ATPase M9.2 subunit;
DE   AltName: Full=Vacuolar proton pump subunit e 1;
GN   Name=ATP6V0E1; Synonyms=ATP6H, ATP6V0E;
DR   GO; GO:0042625; F:ATPase activity, coupled to transmembrane movement of ions; ISS:UniProtKB.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0016049; P:cell growth; IGI:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0043200; P:response to amino acid; IEA:Ensembl.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007035; P:vacuolar acidification; ISS:UniProtKB.
//
ID   VAC14_HUMAN             Reviewed;         782 AA.
AC   Q08AM6; B3KPJ5; Q13174; Q6IA12; Q7L4Y1; Q9BW96; Q9H6V6;
DE   RecName: Full=Protein VAC14 homolog;
DE   AltName: Full=Tax1-binding protein 2;
GN   Name=VAC14; Synonyms=TAX1BP2, TRX;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004872; F:receptor activity; NAS:UniProtKB.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; TAS:Reactome.
DR   GO; GO:0006644; P:phospholipid metabolic process; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VACHT_HUMAN             Reviewed;         532 AA.
AC   Q16572; B2R7S1;
DE   RecName: Full=Vesicular acetylcholine transporter;
DE            Short=VAChT;
DE   AltName: Full=Solute carrier family 18 member 3;
GN   Name=SLC18A3; Synonyms=VACHT;
DR   GuidetoPHARMACOLOGY; 1013; -.
DR   GO; GO:0005277; F:acetylcholine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015870; P:acetylcholine transport; TAS:ProtInc.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
//
ID   VAMP1_HUMAN             Reviewed;         118 AA.
AC   P23763; A8MVP3; D3DUR3; O75468; Q15857; Q6FG94; Q8IVC9;
DE   RecName: Full=Vesicle-associated membrane protein 1;
DE            Short=VAMP-1;
DE   AltName: Full=Synaptobrevin-1;
GN   Name=VAMP1; Synonyms=SYB1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0017157; P:regulation of exocytosis; IBA:RefGenome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   VAMP2_HUMAN             Reviewed;         116 AA.
AC   P63027; P19065; Q9BUC2;
DE   RecName: Full=Vesicle-associated membrane protein 2;
DE            Short=VAMP-2;
DE   AltName: Full=Synaptobrevin-2;
GN   Name=VAMP2; Synonyms=SYB2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0019905; F:syntaxin binding; IBA:RefGenome.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006112; P:energy reserve metabolic process; TAS:Reactome.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0017157; P:regulation of exocytosis; IBA:RefGenome.
DR   GO; GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   VAMP3_HUMAN             Reviewed;         100 AA.
AC   Q15836; Q9BRV4;
DE   RecName: Full=Vesicle-associated membrane protein 3;
DE            Short=VAMP-3;
DE   AltName: Full=Cellubrevin;
DE            Short=CEB;
DE   AltName: Full=Synaptobrevin-3;
GN   Name=VAMP3; Synonyms=SYB3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; IEA:Ensembl.
DR   GO; GO:0006887; P:exocytosis; TAS:ProtInc.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0007269; P:neurotransmitter secretion; IBA:RefGenome.
DR   GO; GO:0001921; P:positive regulation of receptor recycling; ISS:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB.
DR   GO; GO:0034446; P:substrate adhesion-dependent cell spreading; ISS:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; TAS:ProtInc.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISS:UniProtKB.
//
ID   VAMP4_HUMAN             Reviewed;         141 AA.
AC   O75379; A2IDD8; Q96IY9; Q96J20; Q9UEL7;
DE   RecName: Full=Vesicle-associated membrane protein 4;
DE            Short=VAMP-4;
GN   Name=VAMP4;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0006897; P:endocytosis; IBA:RefGenome.
DR   GO; GO:0006887; P:exocytosis; IBA:RefGenome.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0042996; P:regulation of Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0035493; P:SNARE complex assembly; IDA:BHF-UCL.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   VAMP5_HUMAN             Reviewed;         116 AA.
AC   O95183; Q9P0T2;
DE   RecName: Full=Vesicle-associated membrane protein 5;
DE            Short=VAMP-5;
DE   AltName: Full=Myobrevin;
GN   Name=VAMP5; ORFNames=HSPC191;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006887; P:exocytosis; IBA:RefGenome.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; TAS:ProtInc.
DR   GO; GO:0007269; P:neurotransmitter secretion; IBA:RefGenome.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   VAMP7_HUMAN             Reviewed;         220 AA.
AC   P51809; Q53GY7; Q7Z409; Q9H4A7;
DE   RecName: Full=Vesicle-associated membrane protein 7;
DE            Short=VAMP-7;
DE   AltName: Full=Synaptobrevin-like protein 1;
DE   AltName: Full=Tetanus-insensitive VAMP;
DE            Short=Ti-VAMP;
GN   Name=VAMP7; Synonyms=SYBL1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0017156; P:calcium ion-dependent exocytosis; ISS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IBA:RefGenome.
DR   GO; GO:0008333; P:endosome to lysosome transport; IDA:UniProtKB.
DR   GO; GO:0043308; P:eosinophil degranulation; ISS:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:UniProtKB.
DR   GO; GO:0006887; P:exocytosis; IBA:RefGenome.
DR   GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:Ensembl.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043312; P:neutrophil degranulation; ISS:UniProtKB.
DR   GO; GO:0006911; P:phagocytosis, engulfment; ISS:UniProtKB.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:1900483; P:regulation of protein targeting to vacuolar membrane; IEA:Ensembl.
DR   GO; GO:0034197; P:triglyceride transport; IEA:Ensembl.
DR   GO; GO:0006906; P:vesicle fusion; IDA:UniProtKB.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:UniProtKB.
//
ID   VAMP8_HUMAN             Reviewed;         100 AA.
AC   Q9BV40; O60625; Q53SP9; Q6IB09;
DE   RecName: Full=Vesicle-associated membrane protein 8;
DE            Short=VAMP-8;
DE   AltName: Full=Endobrevin;
DE            Short=EDB;
GN   Name=VAMP8;
DR   GO; GO:0005484; F:SNAP receptor activity; IBA:RefGenome.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0000046; P:autophagic vacuole fusion; IMP:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; IBA:RefGenome.
DR   GO; GO:0006887; P:exocytosis; IBA:RefGenome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0030100; P:regulation of endocytosis; IEA:Ensembl.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
//
ID   VANG1_HUMAN             Reviewed;         524 AA.
AC   Q8TAA9; Q5T1D3; Q5T1D4; Q86WG8; Q8N559;
DE   RecName: Full=Vang-like protein 1;
DE   AltName: Full=Loop-tail protein 2 homolog;
DE            Short=LPP2;
DE   AltName: Full=Strabismus 2;
DE   AltName: Full=Van Gogh-like protein 1;
GN   Name=VANGL1; Synonyms=STB2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:InterPro.
//
ID   VANG2_HUMAN             Reviewed;         521 AA.
AC   Q9ULK5; D3DVE9; Q5T212;
DE   RecName: Full=Vang-like protein 2;
DE   AltName: Full=Loop-tail protein 1 homolog;
DE   AltName: Full=Strabismus 1;
DE   AltName: Full=Van Gogh-like protein 2;
GN   Name=VANGL2; Synonyms=KIAA1215, STB1;
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0045176; P:apical protein localization; ISS:UniProtKB.
DR   GO; GO:0035787; P:cell migration involved in kidney development; ISS:UniProtKB.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0060028; P:convergent extension involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0022007; P:convergent extension involved in neural plate elongation; IEA:Ensembl.
DR   GO; GO:0048546; P:digestive tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0048105; P:establishment of body hair planar orientation; IEA:Ensembl.
DR   GO; GO:0001736; P:establishment of planar polarity; ISS:UniProtKB.
DR   GO; GO:0090177; P:establishment of planar polarity involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IEA:Ensembl.
DR   GO; GO:0032835; P:glomerulus development; IEA:Ensembl.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; ISS:UniProtKB.
DR   GO; GO:0060122; P:inner ear receptor stereocilium organization; IEA:Ensembl.
DR   GO; GO:0060993; P:kidney morphogenesis; IEA:Ensembl.
DR   GO; GO:0060490; P:lateral sprouting involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0003149; P:membranous septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0003150; P:muscular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; ISS:UniProtKB.
DR   GO; GO:0035058; P:nonmotile primary cilium assembly; ISS:UniProtKB.
DR   GO; GO:0060488; P:orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis; IEA:Ensembl.
DR   GO; GO:0003402; P:planar cell polarity pathway involved in axis elongation; IEA:Ensembl.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0060489; P:planar dichotomous subdivision of terminal units involved in lung branching morphogenesis; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:Ensembl.
DR   GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   VAPA_HUMAN              Reviewed;         249 AA.
AC   Q9P0L0; A6NDZ0; D3DUI3; O75453; Q5U0E7; Q9UBZ2;
DE   RecName: Full=Vesicle-associated membrane protein-associated protein A;
DE            Short=VAMP-A;
DE            Short=VAMP-associated protein A;
DE            Short=VAP-A;
DE   AltName: Full=33 kDa VAMP-associated protein;
DE            Short=VAP-33;
GN   Name=VAPA; Synonyms=VAP33;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0008219; P:cell death; IMP:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0031175; P:neuron projection development; IMP:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0070972; P:protein localization to endoplasmic reticulum; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   VAPB_HUMAN              Reviewed;         243 AA.
AC   O95292; A2A2F2; O95293; Q9P0H0;
DE   RecName: Full=Vesicle-associated membrane protein-associated protein B/C;
DE            Short=VAMP-B/VAMP-C;
DE            Short=VAMP-associated protein B/C;
DE            Short=VAP-B/VAP-C;
GN   Name=VAPB; ORFNames=UNQ484/PRO983;
DR   GO; GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; IDA:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:0019048; P:modulation by virus of host morphology or physiology; IDA:UniProtKB.
DR   GO; GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
DR   GO; GO:0006665; P:sphingolipid metabolic process; TAS:Reactome.
//
ID   VAS1L_HUMAN             Reviewed;         224 AA.
AC   Q52LC2;
DE   RecName: Full=V-type proton ATPase subunit S1-like protein;
DE   AltName: Full=Vacuolar proton pump subunit S1-like protein;
GN   Name=ATP6AP1L;
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
//
ID   VASH1_HUMAN             Reviewed;         365 AA.
AC   Q7L8A9; Q96H02; Q9UBF4; Q9Y629;
DE   RecName: Full=Vasohibin-1;
GN   Name=VASH1; Synonyms=KIAA1036, VASH;
DR   GO; GO:0001525; P:angiogenesis; IDA:MGI.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0010596; P:negative regulation of endothelial cell migration; IGI:MGI.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:1901491; P:negative regulation of lymphangiogenesis; IGI:MGI.
DR   GO; GO:2000772; P:regulation of cellular senescence; IMP:MGI.
DR   GO; GO:0009611; P:response to wounding; IDA:MGI.
//
ID   VAS1_HUMAN              Reviewed;         470 AA.
AC   Q15904; A6ZKI4;
DE   RecName: Full=V-type proton ATPase subunit S1;
DE            Short=V-ATPase subunit S1;
DE   AltName: Full=Protein XAP-3;
DE   AltName: Full=V-ATPase Ac45 subunit;
DE   AltName: Full=V-ATPase S1 accessory protein;
DE   AltName: Full=Vacuolar proton pump subunit S1;
DE   Flags: Precursor;
GN   Name=ATP6AP1; Synonyms=ATP6IP1, ATP6S1, VATPS1, XAP3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
//
ID   VASH2_HUMAN             Reviewed;         355 AA.
AC   Q86V25; B4DYZ5; Q2VT46; Q5VTE7; Q5VTE9; Q7Z6E3; Q8IZ24; Q9H9W5;
DE   RecName: Full=Vasohibin-2;
DE   AltName: Full=Vasohibin-like protein;
GN   Name=VASH2; Synonyms=VASHL;
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:MGI.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:MGI.
//
ID   VASN_HUMAN              Reviewed;         673 AA.
AC   Q6EMK4; Q6UXL4; Q6UXL5; Q96CX1;
DE   RecName: Full=Vasorin;
DE   AltName: Full=Protein slit-like 2;
DE   Flags: Precursor;
GN   Name=VASN; Synonyms=SLITL2; ORFNames=UNQ314/PRO357/PRO1282;
DR   GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR   GO; GO:0071461; P:cellular response to redox state; IEA:Ensembl.
//
ID   VASP_HUMAN              Reviewed;         380 AA.
AC   P50552; B2RBT9; Q6PIZ1; Q93035;
DE   RecName: Full=Vasodilator-stimulated phosphoprotein;
DE            Short=VASP;
GN   Name=VASP;
DR   GO; GO:0005522; F:profilin binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0034329; P:cell junction assembly; TAS:Reactome.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProt.
DR   GO; GO:0051289; P:protein homotetramerization; IEA:InterPro.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   VAT1L_HUMAN             Reviewed;         419 AA.
AC   Q9HCJ6; Q8IYW8;
DE   RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog-like;
DE            EC=1.-.-.-;
GN   Name=VAT1L; Synonyms=KIAA1576;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   VAT1_HUMAN              Reviewed;         393 AA.
AC   Q99536; A8K345; Q13035; Q5BKZ7; Q96A39; Q9BUT8;
DE   RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog;
DE            EC=1.-.-.-;
GN   Name=VAT1;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010637; P:negative regulation of mitochondrial fusion; IMP:UniProtKB.
//
ID   VATA_HUMAN              Reviewed;         617 AA.
AC   P38606; B2RBR8; D3DN75; Q53YD9; Q96DY6; Q9UHY3;
DE   RecName: Full=V-type proton ATPase catalytic subunit A;
DE            Short=V-ATPase subunit A;
DE            EC=3.6.3.14;
DE   AltName: Full=V-ATPase 69 kDa subunit;
DE   AltName: Full=Vacuolar ATPase isoform VA68;
DE   AltName: Full=Vacuolar proton pump subunit alpha;
GN   Name=ATP6V1A; Synonyms=ATP6A1, ATP6V1A1, VPP2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   VATB1_HUMAN             Reviewed;         513 AA.
AC   P15313; Q53FY0; Q6P4H6;
DE   RecName: Full=V-type proton ATPase subunit B, kidney isoform;
DE            Short=V-ATPase subunit B 1;
DE   AltName: Full=Endomembrane proton pump 58 kDa subunit;
DE   AltName: Full=Vacuolar proton pump subunit B 1;
GN   Name=ATP6V1B1; Synonyms=ATP6B1, VATB, VPP3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0046034; P:ATP metabolic process; IEA:InterPro.
DR   GO; GO:0055074; P:calcium ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0007588; P:excretion; IMP:UniProtKB.
DR   GO; GO:0042472; P:inner ear morphogenesis; IMP:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IMP:HGNC.
DR   GO; GO:0045851; P:pH reduction; IMP:UniProtKB.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; IMP:HGNC.
DR   GO; GO:0006885; P:regulation of pH; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATB2_HUMAN             Reviewed;         511 AA.
AC   P21281; B2R5Z3; D3DSQ5; Q14544; Q15859; Q96IR0;
DE   RecName: Full=V-type proton ATPase subunit B, brain isoform;
DE            Short=V-ATPase subunit B 2;
DE   AltName: Full=Endomembrane proton pump 58 kDa subunit;
DE   AltName: Full=HO57;
DE   AltName: Full=Vacuolar proton pump subunit B 2;
GN   Name=ATP6V1B2; Synonyms=ATP6B2, VPP3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; TAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATC2_HUMAN             Reviewed;         427 AA.
AC   Q8NEY4; Q96EL8;
DE   RecName: Full=V-type proton ATPase subunit C 2;
DE            Short=V-ATPase subunit C 2;
DE   AltName: Full=Vacuolar proton pump subunit C 2;
GN   Name=ATP6V1C2;
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATC1_HUMAN             Reviewed;         382 AA.
AC   P21283;
DE   RecName: Full=V-type proton ATPase subunit C 1;
DE            Short=V-ATPase subunit C 1;
DE   AltName: Full=Vacuolar proton pump subunit C 1;
GN   Name=ATP6V1C1; Synonyms=ATP6C, ATP6D, VATC;
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; TAS:ProtInc.
DR   GO; GO:0005215; F:transporter activity; NAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATD_HUMAN              Reviewed;         247 AA.
AC   Q9Y5K8; B2RE33; Q9Y688;
DE   RecName: Full=V-type proton ATPase subunit D;
DE            Short=V-ATPase subunit D;
DE   AltName: Full=V-ATPase 28 kDa accessory protein;
DE   AltName: Full=Vacuolar proton pump subunit D;
GN   Name=ATP6V1D; Synonyms=ATP6M, VATD;
DR   GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0061512; P:protein localization to cilium; IMP:UniProtKB.
DR   GO; GO:0015992; P:proton transport; IEA:UniProtKB-KW.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATE2_HUMAN             Reviewed;         226 AA.
AC   Q96A05;
DE   RecName: Full=V-type proton ATPase subunit E 2;
DE            Short=V-ATPase subunit E 2;
DE   AltName: Full=Vacuolar proton pump subunit E 2;
GN   Name=ATP6V1E2; Synonyms=ATP6E1, ATP6EL2, ATP6V1EL2;
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATE1_HUMAN             Reviewed;         226 AA.
AC   P36543; A8MUE4; A8MUN4;
DE   RecName: Full=V-type proton ATPase subunit E 1;
DE            Short=V-ATPase subunit E 1;
DE   AltName: Full=V-ATPase 31 kDa subunit;
DE            Short=p31;
DE   AltName: Full=Vacuolar proton pump subunit E 1;
GN   Name=ATP6V1E1; Synonyms=ATP6E, ATP6E2;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATF_HUMAN              Reviewed;         119 AA.
AC   Q16864; C9J2K4; Q6IBA8;
DE   RecName: Full=V-type proton ATPase subunit F;
DE            Short=V-ATPase subunit F;
DE   AltName: Full=V-ATPase 14 kDa subunit;
DE   AltName: Full=Vacuolar proton pump subunit F;
GN   Name=ATP6V1F; Synonyms=ATP6S14, VATF;
DR   GO; GO:0042624; F:ATPase activity, uncoupled; NAS:UniProtKB.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; NAS:UniProtKB.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATG1_HUMAN             Reviewed;         118 AA.
AC   O75348; Q6IB33;
DE   RecName: Full=V-type proton ATPase subunit G 1;
DE            Short=V-ATPase subunit G 1;
DE   AltName: Full=V-ATPase 13 kDa subunit 1;
DE   AltName: Full=Vacuolar proton pump subunit G 1;
DE   AltName: Full=Vacuolar proton pump subunit M16;
GN   Name=ATP6V1G1; Synonyms=ATP6G, ATP6G1, ATP6J;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0016820; F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; IEA:UniProtKB-KW.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATG2_HUMAN             Reviewed;         118 AA.
AC   O95670; B5MEF0; Q2L6F8; Q5HYU8; Q5RJ63;
DE   RecName: Full=V-type proton ATPase subunit G 2;
DE            Short=V-ATPase subunit G 2;
DE   AltName: Full=V-ATPase 13 kDa subunit 2;
DE   AltName: Full=Vacuolar proton pump subunit G 2;
GN   Name=ATP6V1G2; Synonyms=ATP6G, ATP6G2, NG38;
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATG3_HUMAN             Reviewed;         118 AA.
AC   Q96LB4; Q495K2; Q495K4; Q5T9L6;
DE   RecName: Full=V-type proton ATPase subunit G 3;
DE            Short=V-ATPase subunit G 3;
DE   AltName: Full=V-ATPase 13 kDa subunit 3;
DE   AltName: Full=Vacuolar proton pump subunit G 3;
GN   Name=ATP6V1G3; Synonyms=ATP6G3;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VATH_HUMAN              Reviewed;         483 AA.
AC   Q9UI12; B3KMR0; Q6PK44; Q9H3E3; Q9Y300;
DE   RecName: Full=V-type proton ATPase subunit H;
DE            Short=V-ATPase subunit H;
DE   AltName: Full=Nef-binding protein 1;
DE            Short=NBP1;
DE   AltName: Full=Protein VMA13 homolog;
DE   AltName: Full=V-ATPase 50/57 kDa subunits;
DE   AltName: Full=Vacuolar proton pump subunit H;
DE   AltName: Full=Vacuolar proton pump subunit SFD;
GN   Name=ATP6V1H; ORFNames=CGI-11;
DR   GO; GO:0030234; F:enzyme regulator activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; NAS:UniProtKB.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0006897; P:endocytosis; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0050790; P:regulation of catalytic activity; NAS:GOC.
DR   GO; GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0007035; P:vacuolar acidification; NAS:UniProtKB.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   VATL_HUMAN              Reviewed;         155 AA.
AC   P27449; Q6FH26;
DE   RecName: Full=V-type proton ATPase 16 kDa proteolipid subunit;
DE            Short=V-ATPase 16 kDa proteolipid subunit;
DE   AltName: Full=Vacuolar proton pump 16 kDa proteolipid subunit;
GN   Name=ATP6V0C; Synonyms=ATP6C, ATP6L, ATPL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; TAS:UniProtKB.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; TAS:ProtInc.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VATO_HUMAN              Reviewed;         205 AA.
AC   Q99437; D3DPY5; Q6IB32;
DE   RecName: Full=V-type proton ATPase 21 kDa proteolipid subunit;
DE            Short=V-ATPase 21 kDa proteolipid subunit;
DE   AltName: Full=Vacuolar proton pump 21 kDa proteolipid subunit;
DE   AltName: Full=hATPL;
GN   Name=ATP6V0B; Synonyms=ATP6F;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VAV3_HUMAN              Reviewed;         847 AA.
AC   Q9UKW4; B1AMM0; B1APV5; B4E232; B7ZLR1; E9PQ97; O60498; O95230;
AC   Q9Y5X8;
DE   RecName: Full=Guanine nucleotide exchange factor VAV3;
DE            Short=VAV-3;
GN   Name=VAV3;
DR   GO; GO:0005096; F:GTPase activator activity; TAS:ProtInc.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; TAS:GOC.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0009967; P:positive regulation of signal transduction; TAS:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IMP:UniProtKB.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006906; P:vesicle fusion; IEA:Ensembl.
//
ID   VAV2_HUMAN              Reviewed;         878 AA.
AC   P52735; A2RUM4; A8MQ12; B6ZDF5; Q5SYV3; Q5SYV4; Q5SYV5; Q6N012;
AC   Q6PIJ9; Q6Q317;
DE   RecName: Full=Guanine nucleotide exchange factor VAV2;
DE            Short=VAV-2;
GN   Name=VAV2;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IEA:Ensembl.
DR   GO; GO:0043087; P:regulation of GTPase activity; EXP:GOC.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
//
ID   VAV_HUMAN               Reviewed;         845 AA.
AC   P15498; B4DVK9; M0QXX6; Q15860;
DE   RecName: Full=Proto-oncogene vav;
GN   Name=VAV1; Synonyms=VAV;
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; EXP:Reactome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0097190; P:apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038095; P:Fc-epsilon receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:Ensembl.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; TAS:Reactome.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   VAX1_HUMAN              Reviewed;         334 AA.
AC   Q5SQQ9; B1AVW5; Q6ZSX0;
DE   RecName: Full=Ventral anterior homeobox 1;
GN   Name=VAX1;
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   GO; GO:0007406; P:negative regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VAX2_HUMAN              Reviewed;         290 AA.
AC   Q9UIW0; Q53Y33;
DE   RecName: Full=Ventral anterior homeobox 2;
GN   Name=VAX2;
DR   GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0007409; P:axonogenesis; IEA:Ensembl.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IEA:Ensembl.
DR   GO; GO:0007398; P:ectoderm development; TAS:ProtInc.
DR   GO; GO:0048048; P:embryonic eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0060041; P:retina development in camera-type eye; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   VBPC1_HUMAN             Reviewed;         121 AA.
AC   Q6Q795;
DE   RecName: Full=Putative viral protein-binding protein C1;
//
ID   VCAM1_HUMAN             Reviewed;         739 AA.
AC   P19320; A8K6R7; B4DKS4; E9PDD1; Q6NUP8;
DE   RecName: Full=Vascular cell adhesion protein 1;
DE            Short=V-CAM 1;
DE            Short=VCAM-1;
DE   AltName: Full=INCAM-100;
DE   AltName: CD_antigen=CD106;
DE   Flags: Precursor;
GN   Name=VCAM1; Synonyms=L1CAM;
DR   GO; GO:0050839; F:cell adhesion molecule binding; IDA:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IDA:BHF-UCL.
DR   GO; GO:0008131; F:primary amine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0002526; P:acute inflammatory response; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0009308; P:amine metabolic process; IDA:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IC:BHF-UCL.
DR   GO; GO:0007155; P:cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0060326; P:cell chemotaxis; IEA:Ensembl.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IEA:Ensembl.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0060710; P:chorio-allantoic fusion; IEA:Ensembl.
DR   GO; GO:0002544; P:chronic inflammatory response; IEA:Ensembl.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0007157; P:heterophilic cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0007159; P:leukocyte cell-cell adhesion; IDA:BHF-UCL.
DR   GO; GO:0050901; P:leukocyte tethering or rolling; IEP:BHF-UCL.
DR   GO; GO:0022614; P:membrane to membrane docking; IEP:BHF-UCL.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0050776; P:regulation of immune response; TAS:Reactome.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0007584; P:response to nutrient; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VCC1_HUMAN              Reviewed;         119 AA.
AC   Q6UXB2; A8KAC0;
DE   RecName: Full=VEGF coregulated chemokine 1;
DE   AltName: Full=C-X-C motif chemokine 17;
DE   AltName: Full=Dendritic cell and monocyte chemokine-like protein;
DE            Short=DMC;
DE   Flags: Precursor;
GN   Name=CXCL17; Synonyms=VCC1; ORFNames=UNQ473/PRO842;
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
//
ID   VCIP1_HUMAN             Reviewed;        1222 AA.
AC   Q96JH7; Q504T4; Q86T93; Q86W01; Q8N3A9; Q9H5R8;
DE   RecName: Full=Deubiquitinating protein VCIP135;
DE            EC=3.4.19.12;
DE   AltName: Full=Valosin-containing protein p97/p47 complex-interacting protein 1;
DE   AltName: Full=Valosin-containing protein p97/p47 complex-interacting protein p135;
DE            Short=VCP/p47 complex-interacting 135-kDa protein;
GN   Name=VCPIP1; Synonyms=KIAA1850, VCIP135;
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0016320; P:endoplasmic reticulum membrane fusion; IEA:Ensembl.
DR   GO; GO:0090168; P:Golgi reassembly; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:Ensembl.
DR   GO; GO:0035871; P:protein K11-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; ISS:UniProtKB.
//
ID   VCX1_HUMAN              Reviewed;         206 AA.
AC   Q9H320; A0JNS5; Q4V774; Q9P0H3;
DE   RecName: Full=Variable charge X-linked protein 1;
DE   AltName: Full=Variable charge protein on X with ten repeats;
DE            Short=VCX-10r;
DE   AltName: Full=Variably charged protein X-B1;
DE            Short=VCX-B1;
GN   Name=VCX; Synonyms=VCX1, VCX10R, VCXB1;
DR   GO; GO:0003682; F:chromatin binding; TAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:UniProtKB.
DR   GO; GO:0042255; P:ribosome assembly; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   VCX2_HUMAN              Reviewed;         139 AA.
AC   Q9H322; A3KPB6; Q4V9T2; Q9P0H5;
DE   RecName: Full=Variable charge X-linked protein 2;
DE   AltName: Full=Variable charge protein on X with two repeats;
DE            Short=VCX-2r;
DE   AltName: Full=Variably charged protein X-B;
DE            Short=VCX-B;
GN   Name=VCX2; Synonyms=VCX2R, VCXB;
//
ID   VCX3B_HUMAN             Reviewed;         246 AA.
AC   Q9H321; C9JS46; Q4KN12;
DE   RecName: Full=Variable charge X-linked protein 3B;
DE   AltName: Full=Variably charged protein X-C;
DE            Short=VCX-C;
GN   Name=VCX3B; Synonyms=VCXC;
//
ID   VCY1_HUMAN              Reviewed;         125 AA.
AC   O14598;
DE   RecName: Full=Testis-specific basic protein Y 1;
DE   AltName: Full=Basic charge, Y-linked 1;
DE   AltName: Full=Variably charged protein Y;
GN   Name=VCY; Synonyms=BPY1, VCY1A;
GN   and
GN   Name=VCY1B; Synonyms=BPY1B;
//
ID   VCY2_HUMAN              Reviewed;         106 AA.
AC   O14599;
DE   RecName: Full=Testis-specific basic protein Y 2;
DE   AltName: Full=Basic charge, Y-linked 2;
DE   AltName: Full=Variably charged protein Y 2;
GN   Name=BPY2; Synonyms=BPY2A, VCY2, VCY2A;
GN   and
GN   Name=BPY2B; Synonyms=VCY2B;
GN   and
GN   Name=BPY2C; Synonyms=VCY2C;
DR   GO; GO:0032399; F:HECT domain binding; IPI:HGNC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IMP:HGNC.
//
ID   VCX3_HUMAN              Reviewed;         186 AA.
AC   Q9NNX9; Q9P0H4;
DE   RecName: Full=Variable charge X-linked protein 3;
DE   AltName: Full=Variable charge protein on X with eight repeats;
DE            Short=VCX-8r;
DE   AltName: Full=Variably charged protein X-A;
DE            Short=VCX-A;
GN   Name=VCX3A; Synonyms=VCX3, VCX8R, VCXA;
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
//
ID   VDAC1_HUMAN             Reviewed;         283 AA.
AC   P21796; B3KVK4; D3DQ93; Q5FVE7; Q9UIQ5; Q9UPL0;
DE   RecName: Full=Voltage-dependent anion-selective channel protein 1;
DE            Short=VDAC-1;
DE            Short=hVDAC1;
DE   AltName: Full=Outer mitochondrial membrane protein porin 1;
DE   AltName: Full=Plasmalemmal porin;
DE   AltName: Full=Porin 31HL;
DE   AltName: Full=Porin 31HM;
GN   Name=VDAC1; Synonyms=VDAC;
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008308; F:voltage-gated anion channel activity; ISS:UniProtKB.
DR   GO; GO:0006820; P:anion transport; TAS:ProtInc.
DR   GO; GO:0006915; P:apoptotic process; TAS:UniProtKB.
DR   GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0007612; P:learning; IEA:Ensembl.
DR   GO; GO:0007270; P:neuron-neuron synaptic transmission; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VDAC2_HUMAN             Reviewed;         294 AA.
AC   P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6;
DE   RecName: Full=Voltage-dependent anion-selective channel protein 2;
DE            Short=VDAC-2;
DE            Short=hVDAC2;
DE   AltName: Full=Outer mitochondrial membrane protein porin 2;
GN   Name=VDAC2;
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008308; F:voltage-gated anion channel activity; TAS:UniProtKB.
DR   GO; GO:0006820; P:anion transport; TAS:ProtInc.
DR   GO; GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0032272; P:negative regulation of protein polymerization; IEA:Ensembl.
//
ID   VDAC3_HUMAN             Reviewed;         283 AA.
AC   Q9Y277; Q9UIS0;
DE   RecName: Full=Voltage-dependent anion-selective channel protein 3;
DE            Short=VDAC-3;
DE            Short=hVDAC3;
DE   AltName: Full=Outer mitochondrial membrane protein porin 3;
GN   Name=VDAC3;
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0008308; F:voltage-gated anion channel activity; TAS:UniProtKB.
DR   GO; GO:0015853; P:adenine transport; TAS:ProtInc.
//
ID   VDR_HUMAN               Reviewed;         427 AA.
AC   P11473; B2R5Q1; G3V1V9; Q5PSV3;
DE   RecName: Full=Vitamin D3 receptor;
DE            Short=VDR;
DE   AltName: Full=1,25-dihydroxyvitamin D3 receptor;
DE   AltName: Full=Nuclear receptor subfamily 1 group I member 1;
GN   Name=VDR; Synonyms=NR1I1;
DR   GuidetoPHARMACOLOGY; 605; -.
DR   GO; GO:1902098; F:calcitriol binding; IDA:UniProtKB.
DR   GO; GO:0008434; F:calcitriol receptor activity; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:1902121; F:lithocholic acid binding; IDA:UniProtKB.
DR   GO; GO:0038186; F:lithocholic acid receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046965; F:retinoid X receptor binding; IPI:BHF-UCL.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0038183; P:bile acid signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
DR   GO; GO:0000902; P:cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0046697; P:decidualization; IEP:BHF-UCL.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0050892; P:intestinal absorption; IEA:Ensembl.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0060745; P:mammary gland branching involved in pregnancy; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0010839; P:negative regulation of keratinocyte proliferation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0060058; P:positive regulation of apoptotic process involved in mammary gland involution; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.
DR   GO; GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.
DR   GO; GO:0060558; P:regulation of calcidiol 1-monooxygenase activity; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0070561; P:vitamin D receptor signaling pathway; IDA:BHF-UCL.
//
ID   VEGFA_HUMAN             Reviewed;         232 AA.
AC   P15692; B5BU86; H0Y2S8; H0Y407; H0Y414; H0Y462; H0Y8N2; H3BLW7;
AC   O60720; O75875; Q074Z4; Q16889; Q5UB46; Q6P0P5; Q96KJ0; Q96L82;
AC   Q96NW5; Q9H1W8; Q9H1W9; Q9UH58; Q9UL23;
DE   RecName: Full=Vascular endothelial growth factor A;
DE            Short=VEGF-A;
DE   AltName: Full=Vascular permeability factor;
DE            Short=VPF;
DE   Flags: Precursor;
GN   Name=VEGFA; Synonyms=VEGF;
DR   GuidetoPHARMACOLOGY; 2644; -.
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0050840; F:extracellular matrix binding; IC:BHF-UCL.
DR   GO; GO:0001968; F:fibronectin binding; IDA:BHF-UCL.
DR   GO; GO:0008083; F:growth factor activity; IDA:BHF-UCL.
DR   GO; GO:0008201; F:heparin binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:MGI.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0048018; F:receptor agonist activity; IPI:BHF-UCL.
DR   GO; GO:0043183; F:vascular endothelial growth factor receptor 1 binding; IPI:BHF-UCL.
DR   GO; GO:0043184; F:vascular endothelial growth factor receptor 2 binding; IPI:BHF-UCL.
DR   GO; GO:0005172; F:vascular endothelial growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0032147; P:activation of protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0001525; P:angiogenesis; IDA:UniProtKB.
DR   GO; GO:0048844; P:artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0002575; P:basophil chemotaxis; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; ISS:BHF-UCL.
DR   GO; GO:0048593; P:camera-type eye morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0048739; P:cardiac muscle fiber development; ISS:BHF-UCL.
DR   GO; GO:0060948; P:cardiac vascular smooth muscle cell development; ISS:BHF-UCL.
DR   GO; GO:0048469; P:cell maturation; ISS:BHF-UCL.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0071456; P:cellular response to hypoxia; IDA:MGI.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:BHF-UCL.
DR   GO; GO:0071679; P:commissural neuron axon guidance; ISS:BHF-UCL.
DR   GO; GO:0060982; P:coronary artery morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0003169; P:coronary vein morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; ISS:BHF-UCL.
DR   GO; GO:0035767; P:endothelial cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0042462; P:eye photoreceptor cell development; ISS:BHF-UCL.
DR   GO; GO:0040007; P:growth; ISS:BHF-UCL.
DR   GO; GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:BHF-UCL.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0001822; P:kidney development; ISS:BHF-UCL.
DR   GO; GO:0007595; P:lactation; ISS:BHF-UCL.
DR   GO; GO:0030324; P:lung development; ISS:BHF-UCL.
DR   GO; GO:0036303; P:lymph vessel morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0030225; P:macrophage differentiation; IDA:DFLAT.
DR   GO; GO:0060749; P:mammary gland alveolus development; ISS:BHF-UCL.
DR   GO; GO:0007498; P:mesoderm development; ISS:BHF-UCL.
DR   GO; GO:0030224; P:monocyte differentiation; IDA:DFLAT.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:UniProtKB.
DR   GO; GO:0003151; P:outflow tract morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0001541; P:ovarian follicle development; ISS:BHF-UCL.
DR   GO; GO:0001569; P:patterning of blood vessels; ISS:BHF-UCL.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IDA:UniProtKB.
DR   GO; GO:0048842; P:positive regulation of axon extension involved in axon guidance; ISS:BHF-UCL.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:BHF-UCL.
DR   GO; GO:0090050; P:positive regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0038091; P:positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0051272; P:positive regulation of cellular component movement; IDA:BHF-UCL.
DR   GO; GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0038033; P:positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:1901727; P:positive regulation of histone deacetylase activity; IDA:BHF-UCL.
DR   GO; GO:1902533; P:positive regulation of intracellular signal transduction; IDA:BHF-UCL.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; TAS:BHF-UCL.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:BHF-UCL.
DR   GO; GO:0060754; P:positive regulation of mast cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:BHF-UCL.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; ISS:BHF-UCL.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:1900086; P:positive regulation of peptidyl-tyrosine autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0031334; P:positive regulation of protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:1902336; P:positive regulation of retinal ganglion cell axon guidance; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0061419; P:positive regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:BHF-UCL.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0043117; P:positive regulation of vascular permeability; IDA:UniProtKB.
DR   GO; GO:0031077; P:post-embryonic camera-type eye development; ISS:BHF-UCL.
DR   GO; GO:0060319; P:primitive erythrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:BHF-UCL.
DR   GO; GO:0090259; P:regulation of retinal ganglion cell axon guidance; ISS:BHF-UCL.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0043129; P:surfactant homeostasis; ISS:BHF-UCL.
DR   GO; GO:0035148; P:tube formation; IDA:UniProtKB.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001570; P:vasculogenesis; TAS:UniProtKB.
DR   GO; GO:0038190; P:VEGF-activated neuropilin signaling pathway; ISS:BHF-UCL.
//
ID   VEGFB_HUMAN             Reviewed;         207 AA.
AC   P49765; Q16528;
DE   RecName: Full=Vascular endothelial growth factor B;
DE            Short=VEGF-B;
DE   AltName: Full=VEGF-related factor;
DE            Short=VRF;
DE   Flags: Precursor;
GN   Name=VEGFB; Synonyms=VRF;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043183; F:vascular endothelial growth factor receptor 1 binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0060048; P:cardiac muscle contraction; IEA:Ensembl.
DR   GO; GO:0060976; P:coronary vasculature development; IEA:Ensembl.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.
DR   GO; GO:0060754; P:positive regulation of mast cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0035470; P:positive regulation of vascular wound healing; IDA:UniProtKB.
DR   GO; GO:0006493; P:protein O-linked glycosylation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; TAS:Reactome.
//
ID   VEGFC_HUMAN             Reviewed;         419 AA.
AC   P49767; B2R9Q8;
DE   RecName: Full=Vascular endothelial growth factor C;
DE            Short=VEGF-C;
DE   AltName: Full=Flt4 ligand;
DE            Short=Flt4-L;
DE   AltName: Full=Vascular endothelial growth factor-related protein;
DE            Short=VRP;
DE   Flags: Precursor;
GN   Name=VEGFC;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0016331; P:morphogenesis of embryonic epithelium; IEA:Ensembl.
DR   GO; GO:0045776; P:negative regulation of blood pressure; IEA:Ensembl.
DR   GO; GO:0009887; P:organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0050679; P:positive regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:1901492; P:positive regulation of lymphangiogenesis; IEA:Ensembl.
DR   GO; GO:0060754; P:positive regulation of mast cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR   GO; GO:0031954; P:positive regulation of protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0006929; P:substrate-dependent cell migration; TAS:ProtInc.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; TAS:Reactome.
//
ID   VEGFD_HUMAN             Reviewed;         354 AA.
AC   O43915; B2R7Z3;
DE   RecName: Full=Vascular endothelial growth factor D;
DE            Short=VEGF-D;
DE   AltName: Full=c-Fos-induced growth factor;
DE            Short=FIGF;
DE   Flags: Precursor;
GN   Name=FIGF; Synonyms=VEGFD;
DR   GO; GO:0042056; F:chemoattractant activity; IDA:UniProtKB.
DR   GO; GO:0005161; F:platelet-derived growth factor receptor binding; TAS:ProtInc.
DR   GO; GO:0005172; F:vascular endothelial growth factor receptor binding; IPI:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0050930; P:induction of positive chemotaxis; IDA:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0050918; P:positive chemotaxis; IDA:GOC.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0060754; P:positive regulation of mast cell chemotaxis; IDA:UniProtKB.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; TAS:Reactome.
//
ID   VENTX_HUMAN             Reviewed;         258 AA.
AC   O95231; Q32MZ3;
DE   RecName: Full=Homeobox protein VENTX;
DE   AltName: Full=VENT homeobox homolog;
DE   AltName: Full=VENT-like homeobox protein 2;
GN   Name=VENTX; Synonyms=HPX42B, VENTX2;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   VEZA_HUMAN              Reviewed;         779 AA.
AC   Q9HBM0; Q6P1Q3; Q9H2F4; Q9H2U5; Q9NT70; Q9NVW0; Q9UF91;
DE   RecName: Full=Vezatin;
GN   Name=VEZT;
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0043009; P:chordate embryonic development; IEA:Ensembl.
//
ID   VEZF1_HUMAN             Reviewed;         521 AA.
AC   Q14119;
DE   RecName: Full=Vascular endothelial zinc finger 1;
DE   AltName: Full=Putative transcription factor DB1;
DE   AltName: Full=Zinc finger protein 161;
GN   Name=VEZF1; Synonyms=DB1, ZNF161;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0001885; P:endothelial cell development; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   VGFR1_HUMAN             Reviewed;        1338 AA.
AC   P17948; A3E342; A3E344; A8KA71; B0LPF1; B2BF46; B2BF47; B2BF48;
AC   B3FR89; B5A923; F5H5L6; O60722; P16057; Q12954;
DE   RecName: Full=Vascular endothelial growth factor receptor 1;
DE            Short=VEGFR-1;
DE            EC=2.7.10.1;
DE   AltName: Full=Fms-like tyrosine kinase 1;
DE            Short=FLT-1;
DE   AltName: Full=Tyrosine-protein kinase FRT;
DE   AltName: Full=Tyrosine-protein kinase receptor FLT;
DE            Short=FLT;
DE   AltName: Full=Vascular permeability factor receptor;
DE   Flags: Precursor;
GN   Name=FLT1; Synonyms=FLT, FRT, VEGFR1;
DR   GuidetoPHARMACOLOGY; 1812; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019838; F:growth factor binding; IPI:UniProtKB.
DR   GO; GO:0036332; F:placental growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0036326; F:VEGF-A-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0036327; F:VEGF-B-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0048514; P:blood vessel morphogenesis; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0048598; P:embryonic morphogenesis; ISS:UniProtKB.
DR   GO; GO:0002548; P:monocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0001569; P:patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:UniProtKB.
DR   GO; GO:0010863; P:positive regulation of phospholipase C activity; IMP:UniProtKB.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0036323; P:vascular endothelial growth factor receptor-1 signaling pathway; IDA:UniProtKB.
//
ID   VGFR2_HUMAN             Reviewed;        1356 AA.
AC   P35968; A2RRS0; B5A925; C5IFA0; O60723; Q14178;
DE   RecName: Full=Vascular endothelial growth factor receptor 2;
DE            Short=VEGFR-2;
DE            EC=2.7.10.1;
DE   AltName: Full=Fetal liver kinase 1;
DE            Short=FLK-1;
DE   AltName: Full=Kinase insert domain receptor;
DE            Short=KDR;
DE   AltName: Full=Protein-tyrosine kinase receptor flk-1;
DE   AltName: CD_antigen=CD309;
DE   Flags: Precursor;
GN   Name=KDR; Synonyms=FLK1, VEGFR2;
DR   GuidetoPHARMACOLOGY; 1813; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019838; F:growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0051879; F:Hsp90 protein binding; TAS:BHF-UCL.
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:BHF-UCL.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:BHF-UCL.
DR   GO; GO:0038085; F:vascular endothelial growth factor binding; IPI:BHF-UCL.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0001525; P:angiogenesis; TAS:BHF-UCL.
DR   GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl.
DR   GO; GO:0055074; P:calcium ion homeostasis; IEA:Ensembl.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IMP:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR   GO; GO:0002042; P:cell migration involved in sprouting angiogenesis; ISS:BHF-UCL.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0035162; P:embryonic hemopoiesis; ISS:UniProtKB.
DR   GO; GO:0045446; P:endothelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0003158; P:endothelium development; ISS:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
DR   GO; GO:0001945; P:lymph vessel development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IDA:UniProtKB.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0038083; P:peptidyl-tyrosine autophosphorylation; ISS:BHF-UCL.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IDA:BHF-UCL.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IDA:UniProtKB.
DR   GO; GO:0050927; P:positive regulation of positive chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2001214; P:positive regulation of vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:BHF-UCL.
DR   GO; GO:0023014; P:signal transduction by phosphorylation; TAS:GOC.
DR   GO; GO:0043129; P:surfactant homeostasis; IEA:Ensembl.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0038084; P:vascular endothelial growth factor signaling pathway; IDA:GOC.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VGFR3_HUMAN             Reviewed;        1363 AA.
AC   P35916; A8K6L4; B5A926; Q16067; Q86W07; Q86W08;
DE   RecName: Full=Vascular endothelial growth factor receptor 3;
DE            Short=VEGFR-3;
DE            EC=2.7.10.1;
DE   AltName: Full=Fms-like tyrosine kinase 4;
DE            Short=FLT-4;
DE   AltName: Full=Tyrosine-protein kinase receptor FLT4;
DE   Flags: Precursor;
GN   Name=FLT4; Synonyms=VEGFR3;
DR   GuidetoPHARMACOLOGY; 1814; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019838; F:growth factor binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
DR   GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IMP:UniProtKB.
DR   GO; GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IMP:UniProtKB.
DR   GO; GO:0048514; P:blood vessel morphogenesis; ISS:UniProtKB.
DR   GO; GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0001945; P:lymph vessel development; ISS:BHF-UCL.
DR   GO; GO:0001946; P:lymphangiogenesis; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0010575; P:positive regulation vascular endothelial growth factor production; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0060312; P:regulation of blood vessel remodeling; ISS:UniProtKB.
DR   GO; GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.
DR   GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
DR   GO; GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.
DR   GO; GO:0001944; P:vasculature development; ISS:UniProtKB.
//
ID   VGF_HUMAN               Reviewed;         615 AA.
AC   O15240; Q9UDW8;
DE   RecName: Full=Neurosecretory protein VGF;
DE   Contains:
DE     RecName: Full=Neuroendocrine regulatory peptide-1;
DE              Short=NERP-1;
DE   Contains:
DE     RecName: Full=Neuroendocrine regulatory peptide-2;
DE              Short=NERP-2;
DE   Contains:
DE     RecName: Full=Antimicrobial peptide VGF[554-577];
DE   Flags: Precursor;
GN   Name=VGF;
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0051591; P:response to cAMP; IEP:UniProtKB.
DR   GO; GO:0009409; P:response to cold; IEA:Ensembl.
DR   GO; GO:0002021; P:response to dietary excess; IEA:Ensembl.
DR   GO; GO:0032868; P:response to insulin; IEA:Ensembl.
DR   GO; GO:0019953; P:sexual reproduction; IEA:Ensembl.
//
ID   VGLL2_HUMAN             Reviewed;         317 AA.
AC   Q8N8G2; Q8WWX1;
DE   RecName: Full=Transcription cofactor vestigial-like protein 2;
DE            Short=Vgl-2;
DE   AltName: Full=Protein VITO1;
GN   Name=VGLL2; Synonyms=VITO1;
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VGLL1_HUMAN             Reviewed;         258 AA.
AC   Q99990; Q5H915;
DE   RecName: Full=Transcription cofactor vestigial-like protein 1;
DE            Short=Vgl-1;
DE   AltName: Full=Protein TONDU;
GN   Name=VGLL1; Synonyms=TDU;
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VGLL3_HUMAN             Reviewed;         326 AA.
AC   A8MV65; D3DU37; Q504T7;
DE   RecName: Full=Transcription cofactor vestigial-like protein 3;
DE            Short=Vgl-3;
GN   Name=VGLL3;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VGLL4_HUMAN             Reviewed;         290 AA.
AC   Q14135; B4DTS7; J3KN68; Q7L5V0; Q9BQ78;
DE   RecName: Full=Transcription cofactor vestigial-like protein 4;
DE            Short=Vgl-4;
GN   Name=VGLL4; Synonyms=KIAA0121;
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VGLU1_HUMAN             Reviewed;         560 AA.
AC   Q9P2U7; Q6PCD0;
DE   RecName: Full=Vesicular glutamate transporter 1;
DE            Short=VGluT1;
DE   AltName: Full=Brain-specific Na(+)-dependent inorganic phosphate cotransporter;
DE   AltName: Full=Solute carrier family 17 member 7;
GN   Name=SLC17A7; Synonyms=BNPI, VGLUT1;
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; TAS:Reactome.
DR   GO; GO:0015321; F:sodium-dependent phosphate transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015319; F:sodium:inorganic phosphate symporter activity; IDA:MGI.
DR   GO; GO:0014047; P:glutamate secretion; TAS:Reactome.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0051938; P:L-glutamate import; IEA:Ensembl.
DR   GO; GO:0007616; P:long-term memory; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0035435; P:phosphate ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006817; P:phosphate ion transport; TAS:ProtInc.
DR   GO; GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IEA:Ensembl.
DR   GO; GO:0042137; P:sequestering of neurotransmitter; IEA:Ensembl.
DR   GO; GO:0035725; P:sodium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VGLU2_HUMAN             Reviewed;         582 AA.
AC   Q9P2U8; A6NKS2;
DE   RecName: Full=Vesicular glutamate transporter 2;
DE            Short=VGluT2;
DE   AltName: Full=Differentiation-associated BNPI;
DE   AltName: Full=Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter;
DE   AltName: Full=Solute carrier family 17 member 6;
GN   Name=SLC17A6; Synonyms=DNPI, VGLUT2;
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0001504; P:neurotransmitter uptake; IEA:Ensembl.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VGLU3_HUMAN             Reviewed;         589 AA.
AC   Q8NDX2; B3KXZ6; B7ZKV4; Q17RQ8;
DE   RecName: Full=Vesicular glutamate transporter 3;
DE            Short=VGluT3;
DE   AltName: Full=Solute carrier family 17 member 8;
GN   Name=SLC17A8; Synonyms=VGLUT3;
DR   GO; GO:0005313; F:L-glutamate transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VHLL_HUMAN              Reviewed;         139 AA.
AC   Q6RSH7; A1L4M4;
DE   RecName: Full=Von Hippel-Lindau-like protein;
DE            Short=VHL-like protein;
DE            Short=VLP;
GN   Name=VHLL; Synonyms=VLP;
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
//
ID   VHL_HUMAN               Reviewed;         213 AA.
AC   P40337; B2RE45; Q13599; Q6PDA9;
DE   RecName: Full=Von Hippel-Lindau disease tumor suppressor;
DE   AltName: Full=Protein G7;
DE   AltName: Full=pVHL;
GN   Name=VHL;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:Reactome.
DR   GO; GO:0000902; P:cell morphogenesis; NAS:UniProtKB.
DR   GO; GO:0071456; P:cellular response to hypoxia; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; NAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0061428; P:negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; NAS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:BHF-UCL.
DR   GO; GO:0006950; P:response to stress; NAS:UniProtKB.
//
ID   VIAAT_HUMAN             Reviewed;         525 AA.
AC   Q9H598; Q8N489;
DE   RecName: Full=Vesicular inhibitory amino acid transporter;
DE   AltName: Full=GABA and glycine transporter;
DE   AltName: Full=Solute carrier family 32 member 1;
DE   AltName: Full=Vesicular GABA transporter;
DE            Short=hVIAAT;
GN   Name=SLC32A1; Synonyms=VGAT, VIAAT;
DR   GuidetoPHARMACOLOGY; 1133; -.
DR   GO; GO:0015495; F:gamma-aminobutyric acid:proton symporter activity; IEA:Ensembl.
DR   GO; GO:0015187; F:glycine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VIGLN_HUMAN             Reviewed;        1268 AA.
AC   Q00341; B4DTQ2; E7EM71; Q53QU2; Q9UCY3;
DE   RecName: Full=Vigilin;
DE   AltName: Full=High density lipoprotein-binding protein;
DE            Short=HDL-binding protein;
GN   Name=HDLBP; Synonyms=HBP, VGL;
DR   GO; GO:0008289; F:lipid binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008203; P:cholesterol metabolic process; TAS:ProtInc.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
//
ID   VILI_HUMAN              Reviewed;         827 AA.
AC   P09327; B2R9A7; Q53S11; Q96AC8;
DE   RecName: Full=Villin-1;
GN   Name=VIL1; Synonyms=VIL;
DR   GO; GO:0051015; F:actin filament binding; IDA:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IDA:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0035727; F:lysophosphatidic acid binding; IDA:UniProtKB.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0051693; P:actin filament capping; IDA:UniProtKB.
DR   GO; GO:0030042; P:actin filament depolymerization; IDA:UniProtKB.
DR   GO; GO:0030041; P:actin filament polymerization; IDA:UniProtKB.
DR   GO; GO:0051014; P:actin filament severing; IDA:UniProtKB.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; IDA:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEP:UniProt.
DR   GO; GO:0032233; P:positive regulation of actin filament bundle assembly; IDA:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0010634; P:positive regulation of epithelial cell migration; IDA:UniProtKB.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0051125; P:regulation of actin nucleation; IDA:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; IDA:UniProtKB.
DR   GO; GO:2000392; P:regulation of lamellipodium morphogenesis; IEA:Ensembl.
DR   GO; GO:0061041; P:regulation of wound healing; IEA:Ensembl.
DR   GO; GO:0009617; P:response to bacterium; IDA:UniProtKB.
//
ID   VILL_HUMAN              Reviewed;         856 AA.
AC   O15195; A8MZP1; Q9BT80; Q9BWH7;
DE   RecName: Full=Villin-like protein;
GN   Name=VILL;
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
//
ID   VIME_HUMAN              Reviewed;         466 AA.
AC   P08670; B0YJC2; D3DRU4; Q15867; Q15868; Q15869; Q548L2; Q6LER9;
AC   Q8N850; Q96ML2; Q9NTM3;
DE   RecName: Full=Vimentin;
GN   Name=VIM;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:MGI.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProt.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0097110; F:scaffold protein binding; IPI:BHF-UCL.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; IDA:UniProtKB.
DR   GO; GO:0005212; F:structural constituent of eye lens; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0014002; P:astrocyte development; IEA:Ensembl.
DR   GO; GO:0060020; P:Bergmann glial cell differentiation; IEA:Ensembl.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR   GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR   GO; GO:0030049; P:muscle filament sliding; TAS:Reactome.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VINC_HUMAN              Reviewed;        1134 AA.
AC   P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7;
DE   RecName: Full=Vinculin;
DE   AltName: Full=Metavinculin;
DE            Short=MV;
GN   Name=VCL;
DR   GO; GO:0003779; F:actin binding; IDA:BHF-UCL.
DR   GO; GO:0045294; F:alpha-catenin binding; IPI:UniProtKB.
DR   GO; GO:0008013; F:beta-catenin binding; ISS:BHF-UCL.
DR   GO; GO:0045296; F:cadherin binding; ISS:BHF-UCL.
DR   GO; GO:0002162; F:dystroglycan binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0034333; P:adherens junction assembly; IMP:BHF-UCL.
DR   GO; GO:0043297; P:apical junction assembly; IMP:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; TAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; TAS:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:UniProtKB.
DR   GO; GO:0090136; P:epithelial cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.
DR   GO; GO:0002009; P:morphogenesis of an epithelium; IMP:BHF-UCL.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0030336; P:negative regulation of cell migration; TAS:UniProtKB.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0034394; P:protein localization to cell surface; IMP:BHF-UCL.
//
ID   VINEX_HUMAN             Reviewed;         671 AA.
AC   O60504; Q5BJE4; Q6NX54; Q96FY4; Q9UQE4;
DE   RecName: Full=Vinexin;
DE   AltName: Full=SH3-containing adapter molecule 1;
DE            Short=SCAM-1;
DE   AltName: Full=Sorbin and SH3 domain-containing protein 3;
GN   Name=SORBS3; Synonyms=SCAM1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
DR   GO; GO:0017166; F:vinculin binding; IPI:UniProtKB.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0031589; P:cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0006936; P:muscle contraction; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051495; P:positive regulation of cytoskeleton organization; NAS:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IDA:UniProtKB.
//
ID   VIP1_HUMAN              Reviewed;        1433 AA.
AC   Q6PFW1; O15082; Q5HYF8; Q7Z3A7; Q86TE7; Q86UV3; Q86UV4; Q86XW8;
AC   Q8IZN0;
DE   RecName: Full=Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1;
DE            EC=2.7.4.21;
DE            EC=2.7.4.24;
DE   AltName: Full=Diphosphoinositol pentakisphosphate kinase 1;
DE   AltName: Full=Histidine acid phosphatase domain-containing protein 2A;
DE   AltName: Full=IP6 kinase;
DE   AltName: Full=Inositol pyrophosphate synthase 1;
DE   AltName: Full=InsP6 and PP-IP5 kinase 1;
DE   AltName: Full=VIP1 homolog;
DE            Short=hsVIP1;
GN   Name=PPIP5K1; Synonyms=HISPPD2A, IP6K, IPS1, KIAA0377, VIP1;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0033857; F:diphosphoinositol-pentakisphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IDA:UniProtKB.
DR   GO; GO:0000827; F:inositol-1,3,4,5,6-pentakisphosphate kinase activity; IDA:UniProtKB.
DR   GO; GO:0006020; P:inositol metabolic process; IDA:UniProtKB.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   VIP2_HUMAN              Reviewed;        1243 AA.
AC   O43314; A1NI53; A6NGS8; Q8TB50;
DE   RecName: Full=Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2;
DE            EC=2.7.4.21;
DE            EC=2.7.4.24;
DE   AltName: Full=Diphosphoinositol pentakisphosphate kinase 2;
DE   AltName: Full=Histidine acid phosphatase domain-containing protein 1;
DE   AltName: Full=InsP6 and PP-IP5 kinase 2;
DE   AltName: Full=VIP1 homolog 2;
DE            Short=hsVIP2;
GN   Name=PPIP5K2; Synonyms=HISPPD1, KIAA0433, VIP2;
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0033857; F:diphosphoinositol-pentakisphosphate kinase activity; ISS:UniProtKB.
DR   GO; GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000832; F:inositol hexakisphosphate 5-kinase activity; ISS:UniProtKB.
DR   GO; GO:0000827; F:inositol-1,3,4,5,6-pentakisphosphate kinase activity; ISS:UniProtKB.
DR   GO; GO:0006020; P:inositol metabolic process; ISS:UniProtKB.
DR   GO; GO:0043647; P:inositol phosphate metabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   VIPR1_HUMAN             Reviewed;         457 AA.
AC   P32241; A5JUT9; B3KPV1; B4DEB5; B4DGI4; F5H1F5; G3V0I1; Q15871;
AC   Q6P2M6;
DE   RecName: Full=Vasoactive intestinal polypeptide receptor 1;
DE            Short=VIP-R-1;
DE   AltName: Full=Pituitary adenylate cyclase-activating polypeptide type II receptor;
DE            Short=PACAP type II receptor;
DE            Short=PACAP-R-2;
DE            Short=PACAP-R2;
DE   AltName: Full=VPAC1;
DE   Flags: Precursor;
GN   Name=VIPR1;
DR   GuidetoPHARMACOLOGY; 371; -.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004999; F:vasoactive intestinal polypeptide receptor activity; TAS:ProtInc.
DR   GO; GO:0007586; P:digestion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0006936; P:muscle contraction; TAS:ProtInc.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0007268; P:synaptic transmission; TAS:ProtInc.
//
ID   VIPR2_HUMAN             Reviewed;         438 AA.
AC   P41587; Q13053; Q15870; Q53Y09; Q9UCW0;
DE   RecName: Full=Vasoactive intestinal polypeptide receptor 2;
DE            Short=VIP-R-2;
DE   AltName: Full=Helodermin-preferring VIP receptor;
DE   AltName: Full=Pituitary adenylate cyclase-activating polypeptide type III receptor;
DE            Short=PACAP type III receptor;
DE            Short=PACAP-R-3;
DE            Short=PACAP-R3;
DE   AltName: Full=VPAC2;
DE   Flags: Precursor;
GN   Name=VIPR2; Synonyms=VIP2R;
DR   GuidetoPHARMACOLOGY; 372; -.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004999; F:vasoactive intestinal polypeptide receptor activity; IEA:InterPro.
DR   GO; GO:0007190; P:activation of adenylate cyclase activity; IEA:Ensembl.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   VIP_HUMAN               Reviewed;         170 AA.
AC   P01282; Q5TCY8; Q5TCY9; Q96QK3;
DE   RecName: Full=VIP peptides;
DE   Contains:
DE     RecName: Full=Intestinal peptide PHV-42;
DE     AltName: Full=Peptide histidine valine 42;
DE   Contains:
DE     RecName: Full=Intestinal peptide PHM-27;
DE     AltName: Full=Peptide histidine methioninamide 27;
DE   Contains:
DE     RecName: Full=Vasoactive intestinal peptide;
DE              Short=VIP;
DE     AltName: Full=Vasoactive intestinal polypeptide;
DE   Flags: Precursor;
GN   Name=VIP;
DR   GO; GO:0005179; F:hormone activity; IDA:BHF-UCL.
DR   GO; GO:0005184; F:neuropeptide hormone activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007589; P:body fluid secretion; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0043267; P:negative regulation of potassium ion transport; IEA:Ensembl.
DR   GO; GO:0048662; P:negative regulation of smooth muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060406; P:positive regulation of penile erection; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:BHF-UCL.
DR   GO; GO:0045909; P:positive regulation of vasodilation; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IDA:BHF-UCL.
DR   GO; GO:0051930; P:regulation of sensory perception of pain; IEA:Ensembl.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:Ensembl.
//
ID   VIR_HUMAN               Reviewed;        1812 AA.
AC   Q69YN4; Q2M1N0; Q6AHX9; Q6NT78; Q7Z6C7; Q8IXH4; Q9BTH4; Q9H9C9;
AC   Q9NWR3; Q9P2B8; Q9UFW1;
DE   RecName: Full=Protein virilizer homolog;
GN   Name=KIAA1429; ORFNames=MSTP054;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
//
ID   VISL1_HUMAN             Reviewed;         191 AA.
AC   P62760; D6W515; P28677; P29103; P42323; Q9UM20;
DE   RecName: Full=Visinin-like protein 1;
DE            Short=VILIP;
DE            Short=VLP-1;
DE   AltName: Full=Hippocalcin-like protein 3;
DE            Short=HLP3;
GN   Name=VSNL1; Synonyms=VISL1;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   VITRN_HUMAN             Reviewed;         678 AA.
AC   Q6UXI7; A1A526; A6NKI9; A8K7Y4; E9PF47; Q6P7T3; Q96DM8; Q96DT1;
AC   Q9UDN0;
DE   RecName: Full=Vitrin;
DE   Flags: Precursor;
GN   Name=VIT; ORFNames=UNQ647/PRO1277;
DR   GO; GO:0005539; F:glycosaminoglycan binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
//
ID   VKGC_HUMAN              Reviewed;         758 AA.
AC   P38435; B4DMC5; E9PEE1; Q14415; Q6GU45;
DE   RecName: Full=Vitamin K-dependent gamma-carboxylase;
DE            EC=4.1.1.90;
DE   AltName: Full=Gamma-glutamyl carboxylase;
DE   AltName: Full=Peptidyl-glutamate 4-carboxylase;
DE   AltName: Full=Vitamin K gamma glutamyl carboxylase;
GN   Name=GGCX; Synonyms=GC;
DR   GuidetoPHARMACOLOGY; 1268; -.
DR   GO; GO:0008488; F:gamma-glutamyl carboxylase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; TAS:Reactome.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
//
ID   VKIND_HUMAN             Reviewed;        1749 AA.
AC   Q76NI1; B0QZC5; Q5T233; Q6ZNH8; Q8TEE5; Q96LV7; Q9C095;
DE   RecName: Full=Protein very KIND;
DE   AltName: Full=Cerebral protein 9;
DE   AltName: Full=KIND domain-containing protein 1;
DE   AltName: Full=Kinase non-catalytic C-lobe domain-containing protein 1;
DE   AltName: Full=Ras-GEF domain-containing family member 2;
GN   Name=KNDC1; Synonyms=C10orf23, KIAA1768, RASGEF2, VKIND;
GN   ORFNames=hucep-9;
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; IEA:Ensembl.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0048814; P:regulation of dendrite morphogenesis; IEA:Ensembl.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
//
ID   VKOR1_HUMAN             Reviewed;         163 AA.
AC   Q9BQB6; A6NIQ6; B2R4Z6; Q6UX90; Q7Z2R4;
DE   RecName: Full=Vitamin K epoxide reductase complex subunit 1;
DE            EC=1.1.4.1;
DE   AltName: Full=Vitamin K1 2,3-epoxide reductase subunit 1;
GN   Name=VKORC1; Synonyms=VKOR; ORFNames=MSTP134, MSTP576, UNQ308/PRO351;
DR   GuidetoPHARMACOLOGY; 2645; -.
DR   GO; GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IDA:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IMP:UniProtKB.
DR   GO; GO:0060348; P:bone development; ISS:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0017144; P:drug metabolic process; IMP:UniProtKB.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; IMP:UniProtKB.
DR   GO; GO:0043687; P:post-translational protein modification; TAS:Reactome.
DR   GO; GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB.
//
ID   VKORL_HUMAN             Reviewed;         176 AA.
AC   Q8N0U8; Q6AHW9; Q6TEK6;
DE   RecName: Full=Vitamin K epoxide reductase complex subunit 1-like protein 1;
DE            Short=VKORC1-like protein 1;
DE            EC=1.1.4.1;
GN   Name=VKORC1L1;
DR   GO; GO:0047057; F:vitamin-K-epoxide reductase (warfarin-sensitive) activity; IDA:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0055114; P:oxidation-reduction process; IDA:GOC.
DR   GO; GO:0017187; P:peptidyl-glutamic acid carboxylation; IMP:UniProtKB.
DR   GO; GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB.
//
ID   VLDLR_HUMAN             Reviewed;         873 AA.
AC   P98155; B2RMZ7; D3DRH6; Q5VVF6;
DE   RecName: Full=Very low-density lipoprotein receptor;
DE            Short=VLDL receptor;
DE            Short=VLDL-R;
DE   Flags: Precursor;
GN   Name=VLDLR;
DR   GO; GO:0034185; F:apolipoprotein binding; IDA:BHF-UCL.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0048306; F:calcium-dependent protein binding; IPI:BHF-UCL.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.
DR   GO; GO:0034437; F:glycoprotein transporter activity; IDA:BHF-UCL.
DR   GO; GO:0005041; F:low-density lipoprotein receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0038025; F:reelin receptor activity; ISS:BHF-UCL.
DR   GO; GO:0034189; F:very-low-density lipoprotein particle binding; IDA:BHF-UCL.
DR   GO; GO:0030229; F:very-low-density lipoprotein particle receptor activity; IDA:BHF-UCL.
DR   GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0034436; P:glycoprotein transport; IDA:BHF-UCL.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0007613; P:memory; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:1900006; P:positive regulation of dendrite development; ISS:BHF-UCL.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0038026; P:reelin-mediated signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0021517; P:ventral spinal cord development; IEA:Ensembl.
DR   GO; GO:0034447; P:very-low-density lipoprotein particle clearance; IDA:BHF-UCL.
//
ID   VMA21_HUMAN             Reviewed;         101 AA.
AC   Q3ZAQ7; A6NKV7; B3KUA9;
DE   RecName: Full=Vacuolar ATPase assembly integral membrane protein VMA21;
DE   AltName: Full=Myopathy with excessive autophagy protein;
GN   Name=VMA21; Synonyms=MEAX, XMEA;
DR   GO; GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; IDA:UniProtKB.
//
ID   VMA5A_HUMAN             Reviewed;         786 AA.
AC   O00534; Q6UN19; Q6UN20; Q9BVF8;
DE   RecName: Full=von Willebrand factor A domain-containing protein 5A;
DE   AltName: Full=Breast cancer suppressor candidate 1;
DE            Short=BCSC-1;
DE   AltName: Full=Loss of heterozygosity 11 chromosomal region 2 gene A protein;
GN   Name=VWA5A; Synonyms=BCSC1, LOH11CR2A;
//
ID   VMAC_HUMAN              Reviewed;         169 AA.
AC   Q2NL98; B3KW55;
DE   RecName: Full=Vimentin-type intermediate filament-associated coiled-coil protein;
GN   Name=VMAC;
//
ID   VMAT1_HUMAN             Reviewed;         525 AA.
AC   P54219; E9PDJ5; Q9BRE4;
DE   RecName: Full=Chromaffin granule amine transporter;
DE   AltName: Full=Solute carrier family 18 member 1;
DE   AltName: Full=Vesicular amine transporter 1;
DE            Short=VAT1;
GN   Name=SLC18A1; Synonyms=VAT1, VMAT1;
DR   GuidetoPHARMACOLOGY; 1011; -.
DR   GO; GO:0015238; F:drug transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008504; F:monoamine transmembrane transporter activity; TAS:UniProtKB.
DR   GO; GO:0015844; P:monoamine transport; TAS:UniProtKB.
DR   GO; GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VMAT2_HUMAN             Reviewed;         514 AA.
AC   Q05940; B2RC96; D3DRC4; Q15876; Q5VW49; Q9H3P6;
DE   RecName: Full=Synaptic vesicular amine transporter;
DE   AltName: Full=Monoamine transporter;
DE   AltName: Full=Solute carrier family 18 member 2;
DE   AltName: Full=Vesicular amine transporter 2;
DE            Short=VAT2;
GN   Name=SLC18A2; Synonyms=SVMT, VMAT2;
DR   GuidetoPHARMACOLOGY; 1012; -.
DR   GO; GO:0005275; F:amine transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0008144; F:drug binding; IEA:Ensembl.
DR   GO; GO:0008504; F:monoamine transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015222; F:serotonin transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0007568; P:aging; IEA:Ensembl.
DR   GO; GO:0071242; P:cellular response to ammonium ion; IEA:Ensembl.
DR   GO; GO:0035690; P:cellular response to drug; IEA:Ensembl.
DR   GO; GO:0016265; P:death; IEA:Ensembl.
DR   GO; GO:0032456; P:endocytic recycling; IEA:Ensembl.
DR   GO; GO:0042593; P:glucose homeostasis; IEA:Ensembl.
DR   GO; GO:0030073; P:insulin secretion; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0015844; P:monoamine transport; TAS:ProtInc.
DR   GO; GO:0051589; P:negative regulation of neurotransmitter transport; IEA:Ensembl.
DR   GO; GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0001975; P:response to amphetamine; IEA:Ensembl.
DR   GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
DR   GO; GO:0051412; P:response to corticosterone; IEA:Ensembl.
DR   GO; GO:0009635; P:response to herbicide; IEA:Ensembl.
DR   GO; GO:0042594; P:response to starvation; IEA:Ensembl.
DR   GO; GO:0010043; P:response to zinc ion; IEA:Ensembl.
DR   GO; GO:0007268; P:synaptic transmission; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VMO1_HUMAN              Reviewed;         202 AA.
AC   Q7Z5L0; C9JQ15; E9PAU9; E9PGP4; Q3SXP1; Q8IUY1;
DE   RecName: Full=Vitelline membrane outer layer protein 1 homolog;
DE   Flags: Precursor;
GN   Name=VMO1; ORFNames=UNQ6350/PRO21055;
DR   GO; GO:0030704; P:vitelline membrane formation; IEA:InterPro.
//
ID   VMP1_HUMAN              Reviewed;         406 AA.
AC   Q96GC9; Q9H0P4; Q9P089;
DE   RecName: Full=Vacuole membrane protein 1;
DE   AltName: Full=Transmembrane protein 49;
GN   Name=VMP1; Synonyms=TDC1, TMEM49; ORFNames=HSPC292;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0034329; P:cell junction assembly; IMP:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; IMP:UniProtKB.
DR   GO; GO:0007566; P:embryo implantation; IEA:Ensembl.
DR   GO; GO:0010506; P:regulation of autophagy; ISS:UniProtKB.
//
ID   VN1R1_HUMAN             Reviewed;         353 AA.
AC   Q9GZP7; B3KSV5; Q7Z5H8; Q7Z5H9;
DE   RecName: Full=Vomeronasal type-1 receptor 1;
DE   AltName: Full=G-protein coupled receptor GPCR24;
DE            Short=hGPCR24;
DE   AltName: Full=V1r-like receptor 1;
DE   AltName: Full=V3r-related gene protein;
DE   AltName: Full=Vomeronasal olfactory receptor chromosome 19 subtype I member 1;
GN   Name=VN1R1; Synonyms=V1RL1, VNR19I1;
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
//
ID   VN1R3_HUMAN             Reviewed;         311 AA.
AC   Q9BXE9;
DE   RecName: Full=Vomeronasal type-1 receptor 3;
DE   AltName: Full=V1r-like receptor 3;
GN   Name=VN1R3; Synonyms=V1RL3; ORFNames=FKSG46;
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
//
ID   VN1R2_HUMAN             Reviewed;         395 AA.
AC   Q8NFZ6; A1L411; Q8TDU4;
DE   RecName: Full=Vomeronasal type-1 receptor 2;
DE   AltName: Full=G-protein coupled receptor GPCR25;
DE            Short=hGPCR25;
DE   AltName: Full=V1r-like receptor 2;
GN   Name=VN1R2; Synonyms=V1RL2;
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
//
ID   VN1R4_HUMAN             Reviewed;         301 AA.
AC   Q7Z5H5; Q2M3E2; Q7Z5H6; Q7Z5H7; Q8TDU2;
DE   RecName: Full=Vomeronasal type-1 receptor 4;
DE   AltName: Full=G-protein coupled receptor GPCR27;
DE            Short=hGPCR27;
DE   AltName: Full=V1r-like receptor 4;
GN   Name=VN1R4; Synonyms=V1RL4;
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
//
ID   VN1R5_HUMAN             Reviewed;         357 AA.
AC   Q7Z5H4; A0AVG1; Q8NEU5; Q8TDU3;
DE   RecName: Full=Vomeronasal type-1 receptor 5;
DE   AltName: Full=G-protein coupled receptor GPCR26;
DE            Short=hGPCR26;
DE   AltName: Full=V1r-like receptor 5;
GN   Name=VN1R5; Synonyms=V1RL5;
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
//
ID   VNN1_HUMAN              Reviewed;         513 AA.
AC   O95497; A8K310; Q4JFW6; Q4VAS7; Q4VAS8; Q4VAS9; Q9UF16; Q9UJF4;
DE   RecName: Full=Pantetheinase;
DE            EC=3.5.1.92;
DE   AltName: Full=Pantetheine hydrolase;
DE   AltName: Full=Tiff66;
DE   AltName: Full=Vascular non-inflammatory molecule 1;
DE            Short=Vanin-1;
DE   Flags: Precursor;
GN   Name=VNN1;
DR   GO; GO:0034235; F:GPI anchor binding; TAS:BHF-UCL.
DR   GO; GO:0017159; F:pantetheine hydrolase activity; IDA:BHF-UCL.
DR   GO; GO:0002526; P:acute inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; ISS:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0002544; P:chronic inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0006954; P:inflammatory response; ISS:BHF-UCL.
DR   GO; GO:0045087; P:innate immune response; ISS:BHF-UCL.
DR   GO; GO:1902176; P:negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress; ISS:BHF-UCL.
DR   GO; GO:0015939; P:pantothenate metabolic process; IDA:BHF-UCL.
DR   GO; GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.
DR   GO; GO:0006979; P:response to oxidative stress; TAS:BHF-UCL.
//
ID   VNN2_HUMAN              Reviewed;         520 AA.
AC   O95498; A0AUZ3; A6NDY1; A8K4E3; A8K7W0; B2DFZ0; B2DFZ1; B2DFZ2;
AC   B2DFZ3; F6XL73; Q2XUN1; Q9UJF3; Q9UMW2;
DE   RecName: Full=Vascular non-inflammatory molecule 2;
DE            Short=Vanin-2;
DE            EC=3.5.1.92;
DE   AltName: Full=Glycosylphosphatidyl inositol-anchored protein GPI-80;
DE   AltName: Full=Protein FOAP-4;
DE   Flags: Precursor;
GN   Name=VNN2;
DR   GO; GO:0017159; F:pantetheine hydrolase activity; IDA:BHF-UCL.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0015939; P:pantothenate metabolic process; IDA:BHF-UCL.
//
ID   VNN3_HUMAN              Reviewed;         501 AA.
AC   Q9NY84; B2DFY0; B2DFY1; B2DFY3; B2DFY5; B2DFY6; B2DFY7; B2DFY8;
AC   Q3SX90; Q9BQY2;
DE   RecName: Full=Vascular non-inflammatory molecule 3;
DE            Short=Vanin-3;
DE            EC=3.5.1.92;
DE   Flags: Precursor;
GN   Name=VNN3;
DR   GO; GO:0017159; F:pantetheine hydrolase activity; NAS:UniProtKB.
DR   GO; GO:0015939; P:pantothenate metabolic process; IEA:Ensembl.
//
ID   VNRL4_HUMAN             Reviewed;         208 AA.
AC   Q8TDU5;
DE   RecName: Full=Putative vomeronasal receptor-like protein 4;
DE   AltName: Full=G-protein coupled receptor GPCR23;
DE            Short=hGPCR23;
GN   Name=VN1R17P; Synonyms=VNRL4;
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
//
ID   VOPP1_HUMAN             Reviewed;         172 AA.
AC   Q96AW1; B0AZU1; B2RAT4; B3KS72; Q6FIE3; Q8NBN8; Q96RE5; Q9H0W4;
DE   RecName: Full=Vesicular, overexpressed in cancer, prosurvival protein 1;
DE   AltName: Full=EGFR-coamplified and overexpressed protein;
DE            Short=ECop;
DE   AltName: Full=Glioblastoma-amplified secreted protein;
DE   AltName: Full=Putative NF-kappa-B-activating protein 055N;
DE   Flags: Precursor;
GN   Name=VOPP1; Synonyms=ECOP, GASP;
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VP13A_HUMAN             Reviewed;        3174 AA.
AC   Q96RL7; Q5JSX9; Q5JSY0; Q5VYR5; Q702P4; Q709D0; Q86YF8; Q96S61;
AC   Q9H995; Q9Y2J1;
DE   RecName: Full=Vacuolar protein sorting-associated protein 13A;
DE   AltName: Full=Chorea-acanthocytosis protein;
DE   AltName: Full=Chorein;
GN   Name=VPS13A; Synonyms=CHAC, KIAA0986;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006895; P:Golgi to endosome transport; NAS:UniProtKB.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; NAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0035176; P:social behavior; IEA:Ensembl.
//
ID   VP13B_HUMAN             Reviewed;        4022 AA.
AC   Q7Z7G8; C9JD30; Q709C6; Q709C7; Q7Z7G4; Q7Z7G5; Q7Z7G6; Q7Z7G7;
AC   Q8NB77; Q9NWV1; Q9Y4E7;
DE   RecName: Full=Vacuolar protein sorting-associated protein 13B;
DE   AltName: Full=Cohen syndrome protein 1;
GN   Name=VPS13B; Synonyms=CHS1, COH1, KIAA0532;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   VP13C_HUMAN             Reviewed;        3753 AA.
AC   Q709C8; Q6ISR4; Q702P2; Q702P3; Q709C9; Q9NXN8; Q9P2C6;
DE   RecName: Full=Vacuolar protein sorting-associated protein 13C;
GN   Name=VPS13C; Synonyms=KIAA1421;
//
ID   VP13D_HUMAN             Reviewed;        4388 AA.
AC   Q5THJ4; J3KP14; Q58F10; Q6MZK9; Q6ZV12; Q709C4; Q709C5; Q86UB4;
AC   Q9NSJ3; Q9UIM0;
DE   RecName: Full=Vacuolar protein sorting-associated protein 13D;
GN   Name=VPS13D; Synonyms=KIAA0453;
//
ID   VP26A_HUMAN             Reviewed;         327 AA.
AC   O75436; A8MZ56; B2RDD3; Q8TBH4; Q9H982;
DE   RecName: Full=Vacuolar protein sorting-associated protein 26A;
DE   AltName: Full=Vesicle protein sorting 26A;
DE            Short=hVPS26;
GN   Name=VPS26A; Synonyms=VPS26;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; NAS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; NAS:UniProtKB.
//
ID   VP26B_HUMAN             Reviewed;         336 AA.
AC   Q4G0F5; Q96A55;
DE   RecName: Full=Vacuolar protein sorting-associated protein 26B;
DE   AltName: Full=Vesicle protein sorting 26B;
GN   Name=VPS26B;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   VP33A_HUMAN             Reviewed;         596 AA.
AC   Q96AX1; Q547V4; Q9H5Q0;
DE   RecName: Full=Vacuolar protein sorting-associated protein 33A;
DE            Short=hVPS33A;
GN   Name=VPS33A;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032418; P:lysosome localization; IDA:UniProtKB.
DR   GO; GO:0032400; P:melanosome localization; IDA:UniProtKB.
DR   GO; GO:0030220; P:platelet formation; ISS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0048070; P:regulation of developmental pigmentation; ISS:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:MGI.
//
ID   VP33B_HUMAN             Reviewed;         617 AA.
AC   Q9H267; Q96K14; Q9NRP6; Q9NSF3;
DE   RecName: Full=Vacuolar protein sorting-associated protein 33B;
DE            Short=hVPS33B;
GN   Name=VPS33B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032418; P:lysosome localization; IDA:UniProtKB.
DR   GO; GO:0032400; P:melanosome localization; IDA:UniProtKB.
DR   GO; GO:0061025; P:membrane fusion; IMP:UniProtKB.
DR   GO; GO:0070889; P:platelet alpha granule organization; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IMP:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:MGI.
//
ID   VP37B_HUMAN             Reviewed;         285 AA.
AC   Q9H9H4;
DE   RecName: Full=Vacuolar protein sorting-associated protein 37B;
DE            Short=hVps37B;
DE   AltName: Full=ESCRT-I complex subunit VPS37B;
GN   Name=VPS37B;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   VP37C_HUMAN             Reviewed;         355 AA.
AC   A5D8V6; Q8N3K4;
DE   RecName: Full=Vacuolar protein sorting-associated protein 37C;
DE            Short=hVps37C;
DE   AltName: Full=ESCRT-I complex subunit VPS37C;
GN   Name=VPS37C; Synonyms=PML39;
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   VP37A_HUMAN             Reviewed;         397 AA.
AC   Q8NEZ2; Q336D5; Q6NW27; Q8N3D7; Q8TBL7; Q96DL9;
DE   RecName: Full=Vacuolar protein sorting-associated protein 37A;
DE            Short=hVps37A;
DE   AltName: Full=ESCRT-I complex subunit VPS37A;
DE   AltName: Full=Hepatocellular carcinoma-related protein 1;
GN   Name=VPS37A; Synonyms=HCRP1;
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   VP37D_HUMAN             Reviewed;         251 AA.
AC   Q86XT2; Q6P2C3;
DE   RecName: Full=Vacuolar protein sorting-associated protein 37D;
DE   AltName: Full=ESCRT-I complex subunit VPS37D;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 24 protein;
GN   Name=VPS37D; Synonyms=WBSCR24;
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   VP9D1_HUMAN             Reviewed;         631 AA.
AC   Q9Y2B5;
DE   RecName: Full=VPS9 domain-containing protein 1;
DE   AltName: Full=Protein ATP-BL;
GN   Name=VPS9D1; Synonyms=ATPBL, C16orf7;
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015986; P:ATP synthesis coupled proton transport; TAS:ProtInc.
//
ID   VPK10_HUMAN             Reviewed;         156 AA.
AC   P10265; Q9UKH6;
DE   RecName: Full=HERV-K_5q33.3 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K10 Pro protein;
DE   AltName: Full=HERV-K107 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK11_HUMAN             Reviewed;         156 AA.
AC   P63129; Q9UKI1;
DE   RecName: Full=HERV-K_22q11.21 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K101 envelope protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK12_HUMAN             Reviewed;         156 AA.
AC   P63131; Q9UKI0;
DE   RecName: Full=HERV-K_1q22 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K(III) Pro protein;
DE   AltName: Full=HERV-K102 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK1_HUMAN              Reviewed;         156 AA.
AC   P63119;
DE   RecName: Full=HERV-K_12q14.1 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK17_HUMAN             Reviewed;         156 AA.
AC   P63125;
DE   RecName: Full=HERV-K_11q22.1 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK2_HUMAN              Reviewed;         156 AA.
AC   Q9Y6I0; Q9UKH5;
DE   RecName: Full=HERV-K_7p22.1 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K(C7) Pro protein;
DE   AltName: Full=HERV-K(HML-2.HOM) Pro protein;
DE   AltName: Full=HERV-K108 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
GN   Name=ERVK6;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK3_HUMAN              Reviewed;         156 AA.
AC   P63120;
DE   RecName: Full=HERV-K_19q12 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K(C19) Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK5_HUMAN              Reviewed;         156 AA.
AC   P63121;
DE   RecName: Full=HERV-K_19p13.11 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K113 envelope protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK6_HUMAN              Reviewed;         156 AA.
AC   P63122;
DE   RecName: Full=HERV-K_8p23.1 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K115 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK7_HUMAN              Reviewed;         156 AA.
AC   P63123;
DE   RecName: Full=HERV-K_1q23.3 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K(C1a) Pro protein;
DE   AltName: Full=HERV-K110 Pro protein;
DE   AltName: Full=HERV-K18 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK9_HUMAN              Reviewed;         156 AA.
AC   P63124;
DE   RecName: Full=HERV-K_5q13.3 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K104 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPK4_HUMAN              Reviewed;         156 AA.
AC   P63127; Q9UKH4;
DE   RecName: Full=HERV-K_6q14.1 provirus ancestral Pro protein;
DE            EC=3.4.23.50;
DE   AltName: Full=HERV-K(C6) Pro protein;
DE   AltName: Full=HERV-K109 Pro protein;
DE   AltName: Full=Protease;
DE   AltName: Full=Proteinase;
DE            Short=PR;
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   VPP1_HUMAN              Reviewed;         837 AA.
AC   Q93050; B7Z3B7; Q8N5G7; Q9NSX0;
DE   RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 1;
DE            Short=V-ATPase 116 kDa isoform a1;
DE   AltName: Full=Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit;
DE   AltName: Full=Vacuolar adenosine triphosphatase subunit Ac116;
DE   AltName: Full=Vacuolar proton pump subunit 1;
DE   AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1;
GN   Name=ATP6V0A1; Synonyms=ATP6N1, ATP6N1A, VPP1;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VPP2_HUMAN              Reviewed;         856 AA.
AC   Q9Y487; A8K026; Q6NUM0;
DE   RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 2;
DE            Short=V-ATPase 116 kDa isoform a2;
DE   AltName: Full=Lysosomal H(+)-transporting ATPase V0 subunit a2;
DE   AltName: Full=TJ6;
DE   AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2;
GN   Name=ATP6V0A2;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VPP3_HUMAN              Reviewed;         830 AA.
AC   Q13488; O75877; Q8WVC5;
DE   RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 3;
DE            Short=V-ATPase 116 kDa isoform a3;
DE   AltName: Full=Osteoclastic proton pump 116 kDa subunit;
DE            Short=OC-116 kDa;
DE            Short=OC116;
DE   AltName: Full=T-cell immune regulator 1;
DE   AltName: Full=T-cell immune response cDNA7 protein;
DE            Short=TIRC7;
DE   AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3;
GN   Name=TCIRG1; Synonyms=ATP6N1C, ATP6V0A3;
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
DR   GO; GO:0015992; P:proton transport; TAS:ProtInc.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VPP4_HUMAN              Reviewed;         840 AA.
AC   Q9HBG4; A4D1R4; A8KA80; Q32M47;
DE   RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 4;
DE            Short=V-ATPase 116 kDa isoform a4;
DE   AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4;
DE   AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform;
GN   Name=ATP6V0A4; Synonyms=ATP6N1B, ATP6N2;
DR   GO; GO:0051117; F:ATPase binding; IPI:UniProtKB.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:Ensembl.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; TAS:Reactome.
DR   GO; GO:0007588; P:excretion; IMP:HGNC.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0051701; P:interaction with host; TAS:Reactome.
DR   GO; GO:0001503; P:ossification; IMP:HGNC.
DR   GO; GO:0090382; P:phagosome maturation; TAS:Reactome.
DR   GO; GO:0015992; P:proton transport; IMP:HGNC.
DR   GO; GO:0006885; P:regulation of pH; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
DR   GO; GO:0033572; P:transferrin transport; TAS:Reactome.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   VPRBP_HUMAN             Reviewed;        1507 AA.
AC   Q9Y4B6; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37;
DE   RecName: Full=Protein VPRBP;
DE   AltName: Full=DDB1- and CUL4-associated factor 1;
DE   AltName: Full=HIV-1 Vpr-binding protein;
DE            Short=VprBP;
DE   AltName: Full=Serine/threonine-protein kinase VPRBP;
DE            EC=2.7.11.1;
DE   AltName: Full=Vpr-interacting protein;
GN   Name=VPRBP; Synonyms=DCAF1, KIAA0800, RIP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:1990244; F:histone kinase activity (H2A-T120 specific); IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
DR   GO; GO:0035212; P:cell competition in a multicellular organism; IMP:UniProtKB.
DR   GO; GO:1990245; P:histone H2A-T120 phosphorylation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0033151; P:V(D)J recombination; ISS:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VPREB_HUMAN             Reviewed;         145 AA.
AC   P12018; B5MCG2;
DE   RecName: Full=Immunoglobulin iota chain;
DE   AltName: Full=CD179 antigen-like family member A;
DE   AltName: Full=Protein VPreB1;
DE   AltName: Full=V(pre)B protein;
DE            Short=VpreB protein;
DE   AltName: CD_antigen=CD179a;
DE   Flags: Precursor;
GN   Name=VPREB1; Synonyms=VPREB;
//
ID   VPRE3_HUMAN             Reviewed;         123 AA.
AC   Q9UKI3; B2R587;
DE   RecName: Full=Pre-B lymphocyte protein 3;
DE   AltName: Full=N27C7-2;
DE   AltName: Full=Protein VPreB3;
DE   Flags: Precursor;
GN   Name=VPREB3; ORFNames=UNQ355/PRO619;
//
ID   VPS11_HUMAN             Reviewed;         941 AA.
AC   Q9H270; Q8WY89; Q96EP8; Q9H6D9; Q9HCS6;
DE   RecName: Full=Vacuolar protein sorting-associated protein 11 homolog;
DE            Short=hVPS11;
DE   AltName: Full=RING finger protein 108;
GN   Name=VPS11; Synonyms=RNF108; ORFNames=PP3476;
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   VPS16_HUMAN             Reviewed;         839 AA.
AC   Q9H269; Q5JUB1; Q8WU31; Q96EE7; Q96N92; Q9H1Q4; Q9H1Q5;
DE   RecName: Full=Vacuolar protein sorting-associated protein 16 homolog;
DE            Short=hVPS16;
GN   Name=VPS16;
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
//
ID   VPS18_HUMAN             Reviewed;         973 AA.
AC   Q9P253; Q8TCG0; Q96DI3; Q9H268;
DE   RecName: Full=Vacuolar protein sorting-associated protein 18 homolog;
DE            Short=hVPS18;
GN   Name=VPS18; Synonyms=KIAA1475;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007032; P:endosome organization; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0007040; P:lysosome organization; IDA:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   VPS25_HUMAN             Reviewed;         176 AA.
AC   Q9BRG1; B2R581;
DE   RecName: Full=Vacuolar protein-sorting-associated protein 25;
DE            Short=hVps25;
DE   AltName: Full=Dermal papilla-derived protein 9;
DE   AltName: Full=ELL-associated protein of 20 kDa;
DE   AltName: Full=ESCRT-II complex subunit VPS25;
GN   Name=VPS25; Synonyms=DERP9, EAP20;
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VPS28_HUMAN             Reviewed;         221 AA.
AC   Q9UK41; Q86VK0;
DE   RecName: Full=Vacuolar protein sorting-associated protein 28 homolog;
DE            Short=H-Vps28;
DE   AltName: Full=ESCRT-I complex subunit VPS28;
GN   Name=VPS28;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0031397; P:negative regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
DR   GO; GO:0019082; P:viral protein processing; TAS:Reactome.
DR   GO; GO:0019068; P:virion assembly; TAS:Reactome.
//
ID   VPS29_HUMAN             Reviewed;         182 AA.
AC   Q9UBQ0; Q502Y5; Q6FIF8; Q6IAH3; Q9H0W0; Q9NRP1; Q9NRU7;
DE   RecName: Full=Vacuolar protein sorting-associated protein 29;
DE            Short=hVPS29;
DE            EC=3.1.3.3;
DE   AltName: Full=PEP11 homolog;
DE   AltName: Full=Vesicle protein sorting 29;
GN   Name=VPS29; ORFNames=DC15, DC7, MDS007;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004647; F:phosphoserine phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   VPS35_HUMAN             Reviewed;         796 AA.
AC   Q96QK1; Q561W2; Q9H016; Q9H096; Q9H4P3; Q9H8J0; Q9NRS7; Q9NVG2;
AC   Q9NX80; Q9NZK2;
DE   RecName: Full=Vacuolar protein sorting-associated protein 35;
DE            Short=hVPS35;
DE   AltName: Full=Maternal-embryonic 3;
DE   AltName: Full=Vesicle protein sorting 35;
GN   Name=VPS35; Synonyms=MEM3; ORFNames=TCCCTA00141;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; NAS:UniProtKB.
//
ID   VPS36_HUMAN             Reviewed;         386 AA.
AC   Q86VN1; A8K125; Q3ZCV7; Q5H9S1; Q5VXB6; Q9H8Z5; Q9Y3E3;
DE   RecName: Full=Vacuolar protein-sorting-associated protein 36;
DE   AltName: Full=ELL-associated protein of 45 kDa;
DE   AltName: Full=ESCRT-II complex subunit VPS36;
GN   Name=VPS36; Synonyms=C13orf9, EAP45; ORFNames=CGI-145;
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VPS39_HUMAN             Reviewed;         886 AA.
AC   Q96JC1; O94869; Q71SQ6; Q7Z3V3; Q96B93; Q96RM0;
DE   RecName: Full=Vam6/Vps39-like protein;
DE   AltName: Full=TRAP1-like protein;
DE            Short=hVam6p;
GN   Name=VPS39; Synonyms=KIAA0770, TLP, VAM6;
DR   GO; GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   VPS41_HUMAN             Reviewed;         854 AA.
AC   P49754; E9PF36; Q86TP8; Q99851; Q99852;
DE   RecName: Full=Vacuolar protein sorting-associated protein 41 homolog;
DE   AltName: Full=S53;
GN   Name=VPS41;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
//
ID   VPS45_HUMAN             Reviewed;         570 AA.
AC   Q9NRW7; D3DUZ9; Q15715; Q5T4P6; Q9Y4Z6;
DE   RecName: Full=Vacuolar protein sorting-associated protein 45;
DE            Short=h-VPS45;
DE            Short=hlVps45;
GN   Name=VPS45; Synonyms=VPS45A, VPS45B;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006886; P:intracellular protein transport; NAS:UniProtKB.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
//
ID   VPS4A_HUMAN             Reviewed;         437 AA.
AC   Q9UN37; B2RCB7; Q8TF07; Q9UI03; Q9Y582;
DE   RecName: Full=Vacuolar protein sorting-associated protein 4A;
DE            EC=3.6.4.6;
DE   AltName: Full=Protein SKD2;
DE   AltName: Full=VPS4-1;
DE            Short=hVPS4;
GN   Name=VPS4A; Synonyms=VPS4;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; NAS:GOC.
DR   GO; GO:0000910; P:cytokinesis; IDA:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IDA:UniProtKB.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   VPS4B_HUMAN             Reviewed;         444 AA.
AC   O75351; Q69HW4; Q9GZS7;
DE   RecName: Full=Vacuolar protein sorting-associated protein 4B;
DE            EC=3.6.4.6;
DE   AltName: Full=Cell migration-inducing gene 1 protein;
DE   AltName: Full=Suppressor of K(+) transport growth defect 1;
DE            Short=Protein SKD1;
GN   Name=VPS4B; Synonyms=SKD1, VPS42; ORFNames=MIG1;
DR   GO; GO:0005524; F:ATP binding; IMP:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IMP:UniProtKB.
DR   GO; GO:0042623; F:ATPase activity, coupled; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0007032; P:endosome organization; IEA:Ensembl.
DR   GO; GO:0032510; P:endosome to lysosome transport via multivesicular body sorting pathway; IMP:UniProtKB.
DR   GO; GO:0032367; P:intracellular cholesterol transport; IMP:UniProtKB.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0006813; P:potassium ion transport; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0033993; P:response to lipid; IDA:UniProtKB.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   VPS51_HUMAN             Reviewed;         782 AA.
AC   Q9UID3; Q6PJV5; Q7L8A6; Q8WZ35; Q96DF4; Q96GR3;
DE   RecName: Full=Vacuolar protein sorting-associated protein 51 homolog;
DE   AltName: Full=Another new gene 2 protein;
DE   AltName: Full=Protein fat-free homolog;
GN   Name=VPS51; Synonyms=ANG2, C11orf2, C11orf3, FFR; ORFNames=PP5382;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB.
//
ID   VPS52_HUMAN             Reviewed;         723 AA.
AC   Q8N1B4; A2BF38; B0UZZ4; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q9NPT5;
DE   RecName: Full=Vacuolar protein sorting-associated protein 52 homolog;
DE   AltName: Full=SAC2 suppressor of actin mutations 2-like protein;
GN   Name=VPS52; Synonyms=SACM2L;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010668; P:ectodermal cell differentiation; IEA:Ensembl.
DR   GO; GO:0048611; P:embryonic ectodermal digestive tract development; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   VPS53_HUMAN             Reviewed;         699 AA.
AC   Q5VIR6; A8K2S8; B3FH42; Q8WYW3; Q9BRR2; Q9BY02; Q9NV25;
DE   RecName: Full=Vacuolar protein sorting-associated protein 53 homolog;
GN   Name=VPS53; ORFNames=PP13624;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   VPS54_HUMAN             Reviewed;         977 AA.
AC   Q9P1Q0; Q5VIR5; Q86YF7; Q8N6G3; Q9NPV0; Q9NT07; Q9NUJ0;
DE   RecName: Full=Vacuolar protein sorting-associated protein 54;
DE   AltName: Full=Hepatocellular carcinoma protein 8;
DE   AltName: Full=Tumor antigen HOM-HCC-8;
DE   AltName: Full=Tumor antigen SLP-8p;
GN   Name=VPS54; Synonyms=HCC8;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0040007; P:growth; IEA:Ensembl.
DR   GO; GO:0048873; P:homeostasis of number of cells within a tissue; IEA:Ensembl.
DR   GO; GO:0050881; P:musculoskeletal movement; IEA:Ensembl.
DR   GO; GO:0060052; P:neurofilament cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
//
ID   VPS72_HUMAN             Reviewed;         364 AA.
AC   Q15906; A6NLK9; A6PW55; Q53GJ2; Q5U0R4;
DE   RecName: Full=Vacuolar protein sorting-associated protein 72 homolog;
DE   AltName: Full=Protein YL-1;
DE   AltName: Full=Transcription factor-like 1;
GN   Name=VPS72; Synonyms=TCFL1, YL1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   VPS8_HUMAN              Reviewed;        1428 AA.
AC   Q8N3P4; A8K8Q8; B9EIQ1; C9JB61; O94896; Q63HP2; Q9BVP9; Q9H9B0;
DE   RecName: Full=Vacuolar protein sorting-associated protein 8 homolog;
GN   Name=VPS8; Synonyms=KIAA0804;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   VRK1_HUMAN              Reviewed;         396 AA.
AC   Q99986; Q3SYL2;
DE   RecName: Full=Serine/threonine-protein kinase VRK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Vaccinia-related kinase 1;
GN   Name=VRK1;
DR   GuidetoPHARMACOLOGY; 2275; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0035175; F:histone kinase activity (H3-S10 specific); IDA:UniProt.
DR   GO; GO:0072354; F:histone kinase activity (H3-T3 specific); IDA:UniProt.
DR   GO; GO:0031493; F:nucleosomal histone binding; IPI:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:UniProt.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0090166; P:Golgi disassembly; IDA:UniProtKB.
DR   GO; GO:0043987; P:histone H3-S10 phosphorylation; IDA:UniProt.
DR   GO; GO:0072355; P:histone H3-T3 phosphorylation; IDA:UniProt.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007077; P:mitotic nuclear envelope disassembly; TAS:Reactome.
DR   GO; GO:0007084; P:mitotic nuclear envelope reassembly; TAS:Reactome.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProt.
//
ID   VRK2_HUMAN              Reviewed;         508 AA.
AC   Q86Y07; B4DKL0; D6W5D4; D6W5D6; Q49AK9; Q53EU9; Q53S39; Q53S77;
AC   Q53TU1; Q86Y08; Q86Y09; Q86Y10; Q86Y11; Q86Y12; Q8IXI5; Q99987;
DE   RecName: Full=Serine/threonine-protein kinase VRK2;
DE            EC=2.7.11.1;
DE   AltName: Full=Vaccinia-related kinase 2;
GN   Name=VRK2;
DR   GuidetoPHARMACOLOGY; 2276; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0034599; P:cellular response to oxidative stress; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; TAS:ProtInc.
DR   GO; GO:2000659; P:regulation of interleukin-1-mediated signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043408; P:regulation of MAPK cascade; IMP:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   VRK3_HUMAN              Reviewed;         474 AA.
AC   Q8IV63; A6NEG5; A8KA53; Q502Y2; Q9P2V8;
DE   RecName: Full=Inactive serine/threonine-protein kinase VRK3;
DE   AltName: Full=Serine/threonine-protein pseudokinase VRK3;
DE   AltName: Full=Vaccinia-related kinase 3;
GN   Name=VRK3;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
DR   GO; GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IEA:Ensembl.
//
ID   VRTN_HUMAN              Reviewed;         702 AA.
AC   Q9H8Y1; Q9NVC7;
DE   RecName: Full=Vertnin;
GN   Name=VRTN; Synonyms=C14orf115;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
//
ID   VS10L_HUMAN             Reviewed;         867 AA.
AC   Q86VR7;
DE   RecName: Full=V-set and immunoglobulin domain-containing protein 10-like;
DE   Flags: Precursor;
GN   Name=VSIG10L;
//
ID   VSI10_HUMAN             Reviewed;         540 AA.
AC   Q8N0Z9; Q9NWQ7;
DE   RecName: Full=V-set and immunoglobulin domain-containing protein 10;
DE   Flags: Precursor;
GN   Name=VSIG10;
//
ID   VSIG1_HUMAN             Reviewed;         387 AA.
AC   Q86XK7; C9J4P2; Q6MZS4;
DE   RecName: Full=V-set and immunoglobulin domain-containing protein 1;
DE   AltName: Full=Cell surface A33 antigen;
DE   AltName: Full=Glycoprotein A34;
DE   Flags: Precursor;
GN   Name=VSIG1; Synonyms=GPA34;
//
ID   VSIG2_HUMAN             Reviewed;         327 AA.
AC   Q96IQ7; O95791; Q9NX42;
DE   RecName: Full=V-set and immunoglobulin domain-containing protein 2;
DE   AltName: Full=Cortical thymocyte-like protein;
DE            Short=CT-like protein;
DE   Flags: Precursor;
GN   Name=VSIG2; Synonyms=CTH, CTXL; ORFNames=UNQ2770/PRO7154;
//
ID   VSIG8_HUMAN             Reviewed;         414 AA.
AC   Q5VU13; Q5VU14;
DE   RecName: Full=V-set and immunoglobulin domain-containing protein 8;
DE   Flags: Precursor;
GN   Name=VSIG8; Synonyms=C1orf204;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   VSIG4_HUMAN             Reviewed;         399 AA.
AC   Q9Y279; Q6UXI4;
DE   RecName: Full=V-set and immunoglobulin domain-containing protein 4;
DE   AltName: Full=Protein Z39Ig;
DE   Flags: Precursor;
GN   Name=VSIG4; Synonyms=CRIg, Z39IG; ORFNames=UNQ317/PRO362;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006957; P:complement activation, alternative pathway; IEA:UniProtKB-KW.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IEA:Ensembl.
DR   GO; GO:0042130; P:negative regulation of T cell proliferation; IEA:Ensembl.
//
ID   VSTM1_HUMAN             Reviewed;         236 AA.
AC   Q6UX27; D2DJS3; D2DJS4; Q496B6; Q496B7;
DE   RecName: Full=V-set and transmembrane domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=VSTM1; ORFNames=UNQ3033/PRO9835;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
//
ID   VSTM4_HUMAN             Reviewed;         320 AA.
AC   Q8IW00; B4DNI6; Q96MX7;
DE   RecName: Full=V-set and transmembrane domain-containing protein 4;
DE   Flags: Precursor;
GN   Name=VSTM4; Synonyms=C10orf72;
//
ID   VSTM5_HUMAN             Reviewed;         200 AA.
AC   A8MXK1;
DE   RecName: Full=V-set and transmembrane domain-containing protein 5;
DE   Flags: Precursor;
GN   Name=VSTM5; Synonyms=C11orf90;
//
ID   VSX1_HUMAN              Reviewed;         365 AA.
AC   Q9NZR4; B9EGJ4; D1MF28; Q0GM60; Q0GM61; Q0GM62; Q0GM63; Q0GM64;
AC   Q0GM65; Q5TF40; Q5TF41; Q9HCU3; Q9NU27;
DE   RecName: Full=Visual system homeobox 1;
DE   AltName: Full=Homeodomain protein RINX;
DE   AltName: Full=Retinal inner nuclear layer homeobox protein;
DE   AltName: Full=Transcription factor VSX1;
GN   Name=VSX1; Synonyms=RINX;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0042551; P:neuron maturation; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060040; P:retinal bipolar neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   VSX2_HUMAN              Reviewed;         361 AA.
AC   P58304; A1A4X6;
DE   RecName: Full=Visual system homeobox 2;
DE   AltName: Full=Ceh-10 homeodomain-containing homolog;
DE   AltName: Full=Homeobox protein CHX10;
GN   Name=VSX2; Synonyms=CHX10, HOX10;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045165; P:cell fate commitment; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060040; P:retinal bipolar neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   VTA1_HUMAN              Reviewed;         307 AA.
AC   Q9NP79; E1P594; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9P0Q0;
DE   RecName: Full=Vacuolar protein sorting-associated protein VTA1 homolog;
DE   AltName: Full=Dopamine-responsive gene 1 protein;
DE            Short=DRG-1;
DE   AltName: Full=LYST-interacting protein 5;
DE            Short=LIP5;
DE   AltName: Full=SKD1-binding protein 1;
DE            Short=SBP1;
GN   Name=VTA1; Synonyms=C6orf55; ORFNames=HSPC228, My012;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   VTCN1_HUMAN             Reviewed;         282 AA.
AC   Q7Z7D3; Q0GN76; Q45VN0; Q5WPZ3; Q6P097; Q9H6B2;
DE   RecName: Full=V-set domain-containing T-cell activation inhibitor 1;
DE   AltName: Full=B7h.5;
DE   AltName: Full=Immune costimulatory protein B7-H4;
DE   AltName: Full=Protein B7S1;
DE   AltName: Full=T-cell costimulatory molecule B7x;
DE   Flags: Precursor;
GN   Name=VTCN1; Synonyms=B7H4; ORFNames=UNQ659/PRO1291;
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   GO; GO:0072643; P:interferon-gamma secretion; IEA:Ensembl.
DR   GO; GO:0072602; P:interleukin-4 secretion; IEA:Ensembl.
DR   GO; GO:0050868; P:negative regulation of T cell activation; IEA:Ensembl.
DR   GO; GO:0001562; P:response to protozoan; IEA:Ensembl.
//
ID   VTDB_HUMAN              Reviewed;         474 AA.
AC   P02774; B4DPP2; D6RAK8; Q16309; Q16310; Q53F31; Q6GTG1;
DE   RecName: Full=Vitamin D-binding protein;
DE            Short=DBP;
DE            Short=VDB;
DE   AltName: Full=Gc-globulin;
DE   AltName: Full=Group-specific component;
DE   Flags: Precursor;
GN   Name=GC;
DR   GO; GO:0003779; F:actin binding; IPI:UniProtKB.
DR   GO; GO:1902118; F:calcidiol binding; IDA:UniProtKB.
DR   GO; GO:0005499; F:vitamin D binding; TAS:ProtInc.
DR   GO; GO:0051183; F:vitamin transporter activity; IEA:InterPro.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:Reactome.
DR   GO; GO:0042359; P:vitamin D metabolic process; TAS:Reactome.
DR   GO; GO:0051180; P:vitamin transport; TAS:ProtInc.
//
ID   VTI1A_HUMAN             Reviewed;         217 AA.
AC   Q96AJ9; A2A307; B4E137; Q5W0D7;
DE   RecName: Full=Vesicle transport through interaction with t-SNAREs homolog 1A;
DE   AltName: Full=Vesicle transport v-SNARE protein Vti1-like 2;
DE   AltName: Full=Vti1-rp2;
GN   Name=VTI1A;
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:HGNC.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:UniProtKB.
//
ID   VTI1B_HUMAN             Reviewed;         232 AA.
AC   Q9UEU0; O43547; Q96J28;
DE   RecName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B;
DE   AltName: Full=Vesicle transport v-SNARE protein Vti1-like 1;
DE   AltName: Full=Vti1-rp1;
GN   Name=VTI1B; Synonyms=VTI1, VTI1L, VTI1L1, VTI2;
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0061025; P:membrane fusion; TAS:ProtInc.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; TAS:ProtInc.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
//
ID   VTM2A_HUMAN             Reviewed;         236 AA.
AC   Q8TAG5; A4D2E9; B5MC94;
DE   RecName: Full=V-set and transmembrane domain-containing protein 2A;
DE   Flags: Precursor;
GN   Name=VSTM2A; Synonyms=VSTM2;
//
ID   VTM2B_HUMAN             Reviewed;         285 AA.
AC   A6NLU5;
DE   RecName: Full=V-set and transmembrane domain-containing protein 2B;
DE   Flags: Precursor;
GN   Name=VSTM2B;
//
ID   VTM2L_HUMAN             Reviewed;         204 AA.
AC   Q96N03; E1P5V7; Q5JWZ4; Q5JWZ5; Q8ND45; Q9BR37;
DE   RecName: Full=V-set and transmembrane domain-containing protein 2-like protein;
DE   Flags: Precursor;
GN   Name=VSTM2L; Synonyms=C20orf102;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   VTNC_HUMAN              Reviewed;         478 AA.
AC   P04004; B2R7G0; P01141; Q9BSH7;
DE   RecName: Full=Vitronectin;
DE            Short=VN;
DE   AltName: Full=S-protein;
DE   AltName: Full=Serum-spreading factor;
DE   AltName: Full=V75;
DE   Contains:
DE     RecName: Full=Vitronectin V65 subunit;
DE   Contains:
DE     RecName: Full=Vitronectin V10 subunit;
DE   Contains:
DE     RecName: Full=Somatomedin-B;
DE   Flags: Precursor;
GN   Name=VTN;
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005178; F:integrin binding; IPI:BHF-UCL.
DR   GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0033627; P:cell adhesion mediated by integrin; IDA:BHF-UCL.
DR   GO; GO:0007160; P:cell-matrix adhesion; IDA:BHF-UCL.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030195; P:negative regulation of blood coagulation; IC:BHF-UCL.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IDA:BHF-UCL.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IDA:BHF-UCL.
DR   GO; GO:0014911; P:positive regulation of smooth muscle cell migration; IDA:BHF-UCL.
DR   GO; GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:BHF-UCL.
DR   GO; GO:0090303; P:positive regulation of wound healing; IC:BHF-UCL.
DR   GO; GO:0030449; P:regulation of complement activation; TAS:Reactome.
DR   GO; GO:0061302; P:smooth muscle cell-matrix adhesion; IDA:BHF-UCL.
//
ID   VW5B1_HUMAN             Reviewed;        1220 AA.
AC   Q5TIE3; A4IF35; A4IF36; Q3ZCM4; Q6ZUB4; Q96M71;
DE   RecName: Full=von Willebrand factor A domain-containing protein 5B1;
DE   Flags: Precursor;
GN   Name=VWA5B1;
//
ID   VW5B2_HUMAN             Reviewed;        1253 AA.
AC   Q8N398; B9EGN7;
DE   RecName: Full=von Willebrand factor A domain-containing protein 5B2;
GN   Name=VWA5B2;
//
ID   VWA1_HUMAN              Reviewed;         445 AA.
AC   Q6PCB0; A8K692; B3KUA1; E9PB53; Q7L5D7; Q9H6J5;
DE   RecName: Full=von Willebrand factor A domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=VWA1;
DR   GO; GO:0048266; P:behavioral response to pain; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
//
ID   VWA2_HUMAN              Reviewed;         755 AA.
AC   Q5GFL6; A1A5D4; B5MDJ8; Q6ZS39; Q6ZWJ7; Q708C5; Q70UZ8;
DE   RecName: Full=von Willebrand factor A domain-containing protein 2;
DE   AltName: Full=A domain-containing protein similar to matrilin and collagen;
DE            Short=AMACO;
DE   AltName: Full=Colon cancer secreted protein 2;
DE            Short=CCSP-2;
DE   Flags: Precursor;
GN   Name=VWA2; Synonyms=AMACO;
DR   GO; GO:0007161; P:calcium-independent cell-matrix adhesion; IEA:Ensembl.
//
ID   VWA3A_HUMAN             Reviewed;        1184 AA.
AC   A6NCI4; A4QMU8; A6NNC0; Q6UTX4; Q6ZQZ9; Q8IUY6; Q8N9W1;
DE   RecName: Full=von Willebrand factor A domain-containing protein 3A;
DE   Flags: Precursor;
GN   Name=VWA3A;
//
ID   VWA3B_HUMAN             Reviewed;        1294 AA.
AC   Q502W6; B9EK71; Q86T73; Q8N2D0; Q8N770; Q8NA79; Q8ND63; Q8ND65;
AC   Q8WW02;
DE   RecName: Full=von Willebrand factor A domain-containing protein 3B;
GN   Name=VWA3B;
//
ID   VWA7_HUMAN              Reviewed;         891 AA.
AC   Q9Y334; A2BEX8; A6NHR6; B0V041; Q5SSR5; Q96QC8; Q9UMP9;
DE   RecName: Full=von Willebrand factor A domain-containing protein 7;
DE   AltName: Full=Protein G7c;
DE   Flags: Precursor;
GN   Name=VWA7; Synonyms=C6orf27, G7C, NG37;
//
ID   VWA8_HUMAN              Reviewed;        1905 AA.
AC   A3KMH1; O60310; Q5JTP6; Q5VW08; Q7Z6I9; Q86YC9; Q8N3E4;
DE   RecName: Full=von Willebrand factor A domain-containing protein 8;
DE   Flags: Precursor;
GN   Name=VWA8; Synonyms=KIAA0564;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
//
ID   VWA9_HUMAN              Reviewed;         518 AA.
AC   Q96SY0; B4DDI6; B4DVD5; Q49AH8; Q96HX5; Q9H0S5;
DE   RecName: Full=von Willebrand factor A domain-containing protein 9;
GN   Name=VWA9; Synonyms=C15orf44;
//
ID   VWC2L_HUMAN             Reviewed;         222 AA.
AC   B2RUY7; A6NC69; B2RUW7; B7X8X1;
DE   RecName: Full=von Willebrand factor C domain-containing protein 2-like;
DE   AltName: Full=Brorin-like;
DE   Flags: Precursor;
GN   Name=VWC2L;
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
//
ID   VWC2_HUMAN              Reviewed;         325 AA.
AC   Q2TAL6; Q6UXE2;
DE   RecName: Full=Brorin;
DE   AltName: Full=Brain-specific chordin-like protein;
DE   AltName: Full=von Willebrand factor C domain-containing protein 2;
DE   Flags: Precursor;
GN   Name=VWC2; ORFNames=UNQ739/PRO1434;
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; ISS:HGNC.
DR   GO; GO:0010811; P:positive regulation of cell-substrate adhesion; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:HGNC.
//
ID   VWCE_HUMAN              Reviewed;         955 AA.
AC   Q96DN2; A5PKV0; Q7Z7L6; Q86WK8;
DE   RecName: Full=von Willebrand factor C and EGF domain-containing protein;
DE   AltName: Full=HBV X protein up-regulated gene 11 protein;
DE   AltName: Full=HBxAg up-regulated gene 11 protein;
DE   Flags: Precursor;
GN   Name=VWCE; Synonyms=URG11;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   VWDE_HUMAN              Reviewed;        1590 AA.
AC   Q8N2E2; Q96SQ3;
DE   RecName: Full=von Willebrand factor D and EGF domain-containing protein;
DE   Flags: Precursor;
GN   Name=VWDE;
//
ID   VWF_HUMAN               Reviewed;        2813 AA.
AC   P04275; Q99806;
DE   RecName: Full=von Willebrand factor;
DE            Short=vWF;
DE   Contains:
DE     RecName: Full=von Willebrand antigen 2;
DE     AltName: Full=von Willebrand antigen II;
DE   Flags: Precursor;
GN   Name=VWF; Synonyms=F8VWF;
DR   GO; GO:0051087; F:chaperone binding; IDA:UniProtKB.
DR   GO; GO:0005518; F:collagen binding; IDA:UniProtKB.
DR   GO; GO:0001948; F:glycoprotein binding; IDA:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0019865; F:immunoglobulin binding; IDA:UniProtKB.
DR   GO; GO:0005178; F:integrin binding; IPI:UniProtKB.
DR   GO; GO:0002020; F:protease binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0007596; P:blood coagulation; IMP:UniProtKB.
DR   GO; GO:0007597; P:blood coagulation, intrinsic pathway; TAS:Reactome.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0031589; P:cell-substrate adhesion; IDA:UniProtKB.
DR   GO; GO:0030198; P:extracellular matrix organization; TAS:Reactome.
DR   GO; GO:0007599; P:hemostasis; IMP:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0001890; P:placenta development; IEA:Ensembl.
DR   GO; GO:0030168; P:platelet activation; IDA:UniProtKB.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; TAS:UniProtKB.
//
ID   WAC_HUMAN               Reviewed;         647 AA.
AC   Q9BTA9; A8K2A9; C9JBT9; D3DRW5; D3DRW6; D3DRW7; Q53EN9; Q5JU75;
AC   Q5JU77; Q5VXK0; Q5VXK2; Q8TCK1; Q96DP3; Q96FW6; Q96JI3;
DE   RecName: Full=WW domain-containing adapter protein with coiled-coil;
GN   Name=WAC; Synonyms=KIAA1844;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:UniProtKB.
DR   GO; GO:0044783; P:G1 DNA damage checkpoint; IMP:UniProtKB.
DR   GO; GO:0071894; P:histone H2B conserved C-terminal lysine ubiquitination; IMP:UniProtKB.
DR   GO; GO:0010390; P:histone monoubiquitination; IMP:UniProtKB.
DR   GO; GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0016239; P:positive regulation of macroautophagy; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   WAP53_HUMAN             Reviewed;         548 AA.
AC   Q9BUR4; B3KPR9; D3DTQ4; Q08ET9; Q9NW09;
DE   RecName: Full=Telomerase Cajal body protein 1;
DE   AltName: Full=WD repeat-containing protein 79;
DE   AltName: Full=WD40 repeat-containing protein encoding RNA antisense to p53;
GN   Name=WRAP53; Synonyms=TCAB1, WDR79;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0051973; P:positive regulation of telomerase activity; IDA:UniProtKB.
DR   GO; GO:0032203; P:telomere formation via telomerase; IMP:UniProtKB.
//
ID   WAPL_HUMAN              Reviewed;        1190 AA.
AC   Q7Z5K2; A7E2B5; Q5VSK5; Q8IX10; Q92549;
DE   RecName: Full=Wings apart-like protein homolog;
DE   AltName: Full=Friend of EBNA2 protein;
GN   Name=WAPAL; Synonyms=FOE, KIAA0261, WAPL;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0035562; P:negative regulation of chromatin binding; IMP:UniProtKB.
DR   GO; GO:0008156; P:negative regulation of DNA replication; IMP:UniProtKB.
DR   GO; GO:0045875; P:negative regulation of sister chromatid cohesion; IMP:UniProtKB.
DR   GO; GO:0071168; P:protein localization to chromatin; IMP:UniProtKB.
DR   GO; GO:0071922; P:regulation of cohesin localization to chromatin; IMP:UniProtKB.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   WASF1_HUMAN             Reviewed;         559 AA.
AC   Q92558; E1P5F2; Q5SZK7;
DE   RecName: Full=Wiskott-Aldrich syndrome protein family member 1;
DE            Short=WASP family protein member 1;
DE   AltName: Full=Protein WAVE-1;
DE   AltName: Full=Verprolin homology domain-containing protein 1;
GN   Name=WASF1; Synonyms=KIAA0269, SCAR1, WAVE1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0032403; F:protein complex binding; IMP:UniProt.
DR   GO; GO:0030041; P:actin filament polymerization; TAS:ProtInc.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0072673; P:lamellipodium morphogenesis; IEA:Ensembl.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IMP:UniProt.
DR   GO; GO:0006461; P:protein complex assembly; NAS:ProtInc.
DR   GO; GO:0016601; P:Rac protein signal transduction; IMP:UniProt.
//
ID   WASF3_HUMAN             Reviewed;         502 AA.
AC   Q9UPY6; O94974; Q86VQ2;
DE   RecName: Full=Wiskott-Aldrich syndrome protein family member 3;
DE            Short=WASP family protein member 3;
DE   AltName: Full=Protein WAVE-3;
DE   AltName: Full=Verprolin homology domain-containing protein 3;
GN   Name=WASF3; Synonyms=KIAA0900, SCAR3, WAVE3;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0030041; P:actin filament polymerization; TAS:ProtInc.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IEA:Ensembl.
DR   GO; GO:0031643; P:positive regulation of myelination; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
//
ID   WASF2_HUMAN             Reviewed;         498 AA.
AC   Q9Y6W5; B4DZN0; O60794; Q9UDY7;
DE   RecName: Full=Wiskott-Aldrich syndrome protein family member 2;
DE            Short=WASP family protein member 2;
DE   AltName: Full=Protein WAVE-2;
DE   AltName: Full=Verprolin homology domain-containing protein 2;
GN   Name=WASF2; Synonyms=WAVE2;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProt.
DR   GO; GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.
DR   GO; GO:0030048; P:actin filament-based movement; IEA:Ensembl.
DR   GO; GO:0007188; P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0001667; P:ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0001525; P:angiogenesis; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0072673; P:lamellipodium morphogenesis; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProt.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IMP:UniProt.
DR   GO; GO:0016601; P:Rac protein signal transduction; IEA:Ensembl.
//
ID   WASH1_HUMAN             Reviewed;         465 AA.
AC   A8K0Z3;
DE   RecName: Full=WAS protein family homolog 1;
DE   AltName: Full=CXYorf1-like protein on chromosome 9;
DE   AltName: Full=Protein FAM39E;
GN   Name=WASH1; Synonyms=FAM39E;
DR   GO; GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
//
ID   WASH2_HUMAN             Reviewed;         465 AA.
AC   Q6VEQ5;
DE   RecName: Full=WAS protein family homolog 2;
DE   AltName: Full=CXYorf1-like protein on chromosome 2;
DE   AltName: Full=Protein FAM39B;
GN   Name=WASH2P; Synonyms=FAM39B;
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   WASH3_HUMAN             Reviewed;         463 AA.
AC   C4AMC7;
DE   RecName: Full=Putative WAS protein family homolog 3;
DE   AltName: Full=Protein FAM39DP;
GN   Name=WASH3P; Synonyms=FAM39DP;
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IDA:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   WASH6_HUMAN             Reviewed;         447 AA.
AC   Q9NQA3; A6NGF1; Q8N305;
DE   RecName: Full=WAS protein family homolog 6;
DE   AltName: Full=Protein FAM39A;
GN   Name=WASH6P; Synonyms=CXYorf1, FAM39A;
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   WASH4_HUMAN             Reviewed;         477 AA.
AC   A8MWX3;
DE   RecName: Full=Putative WAS protein family homolog 4;
DE   AltName: Full=Protein FAM39CP;
GN   Name=WASH4P; Synonyms=FAM39CP;
DR   GO; GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; ISS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; ISS:UniProtKB.
//
ID   WASH7_HUMAN             Reviewed;        1173 AA.
AC   Q2M389; Q2NL83; Q8IW61; Q8N5W7; Q9NVD6; Q9UPW7;
DE   RecName: Full=WASH complex subunit 7;
GN   Name=KIAA1033;
DR   GO; GO:0016197; P:endosomal transport; ISS:UniProtKB.
//
ID   WASL_HUMAN              Reviewed;         505 AA.
AC   O00401; A1JUI9; Q7Z746;
DE   RecName: Full=Neural Wiskott-Aldrich syndrome protein;
DE            Short=N-WASP;
GN   Name=WASL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; TAS:ProtInc.
DR   GO; GO:0007411; P:axon guidance; TAS:Reactome.
DR   GO; GO:0006928; P:cellular component movement; TAS:ProtInc.
DR   GO; GO:0034629; P:cellular protein complex localization; IEA:Ensembl.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006900; P:membrane budding; ISS:BHF-UCL.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
DR   GO; GO:2000370; P:positive regulation of clathrin-mediated endocytosis; ISS:BHF-UCL.
DR   GO; GO:0051491; P:positive regulation of filopodium assembly; ISS:BHF-UCL.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0009617; P:response to bacterium; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0051653; P:spindle localization; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016050; P:vesicle organization; ISS:BHF-UCL.
DR   GO; GO:0030050; P:vesicle transport along actin filament; ISS:BHF-UCL.
//
ID   WASP_HUMAN              Reviewed;         502 AA.
AC   P42768; Q9BU11; Q9UNJ9;
DE   RecName: Full=Wiskott-Aldrich syndrome protein;
DE            Short=WASp;
GN   Name=WAS; Synonyms=IMD2;
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
DR   GO; GO:0030041; P:actin filament polymerization; IEA:Ensembl.
DR   GO; GO:0030048; P:actin filament-based movement; IEA:Ensembl.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:ProtInc.
DR   GO; GO:0006952; P:defense response; TAS:ProtInc.
DR   GO; GO:0016197; P:endosomal transport; IEA:Ensembl.
DR   GO; GO:0008544; P:epidermis development; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0006955; P:immune response; IMP:HGNC.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:2000601; P:positive regulation of Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0050790; P:regulation of catalytic activity; TAS:GOC.
DR   GO; GO:0042110; P:T cell activation; IEA:Ensembl.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
//
ID   WBP1L_HUMAN             Reviewed;         342 AA.
AC   Q9NX94; B3KPF4; B7Z6S7; D3DR90; Q1EG70; Q2HIY7; Q5F2G6;
DE   RecName: Full=WW domain binding protein 1-like;
DE   AltName: Full=Outcome predictor in acute leukemia 1;
GN   Name=WBP1L; Synonyms=C10orf26, OPA1L;
//
ID   WBP11_HUMAN             Reviewed;         641 AA.
AC   Q9Y2W2; Q96AY8;
DE   RecName: Full=WW domain-binding protein 11;
DE            Short=WBP-11;
DE   AltName: Full=Npw38-binding protein;
DE            Short=NpwBP;
DE   AltName: Full=SH3 domain-binding protein SNP70;
DE   AltName: Full=Splicing factor that interacts with PQBP-1 and PP1;
GN   Name=WBP11; Synonyms=NPWBP, SIPP1, SNP70;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008599; F:protein phosphatase type 1 regulator activity; IEA:Ensembl.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   WBP1_HUMAN              Reviewed;         269 AA.
AC   Q96G27; B2RE02; O95637;
DE   RecName: Full=WW domain-binding protein 1;
DE            Short=WBP-1;
GN   Name=WBP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0050699; F:WW domain binding; IPI:UniProtKB.
//
ID   WBP2L_HUMAN             Reviewed;         309 AA.
AC   Q6ICG8; A3KFF7; A8MSG5; B3KXX4; Q8TBF0; Q8TBF3;
DE   RecName: Full=Postacrosomal sheath WW domain-binding protein;
DE   AltName: Full=WW domain-binding protein 2-like;
GN   Name=WBP2NL; Synonyms=PAWP;
DR   GO; GO:0050699; F:WW domain binding; ISS:HGNC.
DR   GO; GO:0007343; P:egg activation; ISS:HGNC.
DR   GO; GO:0035039; P:male pronucleus assembly; ISS:HGNC.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
//
ID   WBP2_HUMAN              Reviewed;         261 AA.
AC   Q969T9; O95638;
DE   RecName: Full=WW domain-binding protein 2;
DE            Short=WBP-2;
GN   Name=WBP2;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   WBP4_HUMAN              Reviewed;         376 AA.
AC   O75554; Q32P29;
DE   RecName: Full=WW domain-binding protein 4;
DE            Short=WBP-4;
DE   AltName: Full=Formin-binding protein 21;
DE   AltName: Full=WW domain-containing-binding protein 4;
GN   Name=WBP4; Synonyms=FBP21, FNBP21;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0070064; F:proline-rich region binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IDA:UniProtKB.
//
ID   WBP5_HUMAN              Reviewed;         104 AA.
AC   Q9UHQ7; B2R5H6;
DE   RecName: Full=WW domain-binding protein 5;
DE            Short=WBP-5;
GN   Name=WBP5;
//
ID   WBS16_HUMAN             Reviewed;         464 AA.
AC   Q96I51; D3DXK0; Q548B1; Q9H0G7;
DE   RecName: Full=Williams-Beuren syndrome chromosomal region 16 protein;
DE   AltName: Full=RCC1-like G exchanging factor-like protein;
GN   Name=WBSCR16;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   WBS22_HUMAN             Reviewed;         281 AA.
AC   O43709; A8K501; C9K060; Q96P12; Q9BQ58; Q9HBP9;
DE   RecName: Full=Ribosome biogenesis methyltransferase WBSCR22;
DE            EC=2.1.1.-;
DE   AltName: Full=Williams-Beuren syndrome chromosomal region 22 protein;
GN   Name=WBSCR22; ORFNames=HUSSY-03, PP3381;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
//
ID   WBS23_HUMAN             Reviewed;         173 AA.
AC   Q9H6D5; A0AVD7;
DE   RecName: Full=Putative Williams-Beuren syndrome chromosomal region 23 protein;
GN   Name=WBSCR23;
//
ID   WBS27_HUMAN             Reviewed;         245 AA.
AC   Q8N6F8;
DE   RecName: Full=Williams-Beuren syndrome chromosomal region 27 protein;
GN   Name=WBSCR27;
//
ID   WBS28_HUMAN             Reviewed;         265 AA.
AC   Q6UE05; Q6UE04; Q8NHP4;
DE   RecName: Full=Williams-Beuren syndrome chromosomal region 28 protein;
GN   Name=WBSCR28;
//
ID   WDFY1_HUMAN             Reviewed;         410 AA.
AC   Q8IWB7; Q53S17; Q9H9D5; Q9P2B3;
DE   RecName: Full=WD repeat and FYVE domain-containing protein 1;
DE   AltName: Full=FENS-1;
DE   AltName: Full=Phosphoinositide-binding protein 1;
DE   AltName: Full=WD40- and FYVE domain-containing protein 1;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 17;
GN   Name=WDFY1; Synonyms=KIAA1435, WDF1, ZFYVE17;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
//
ID   WDFY2_HUMAN             Reviewed;         400 AA.
AC   Q96P53; B1AL86; Q96CS1;
DE   RecName: Full=WD repeat and FYVE domain-containing protein 2;
DE   AltName: Full=WD40- and FYVE domain-containing protein 2;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 22;
GN   Name=WDFY2; Synonyms=WDF2, ZFYVE22;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   WDFY3_HUMAN             Reviewed;        3526 AA.
AC   Q8IZQ1; Q4W5K5; Q6P0Q5; Q8N1T2; Q8NAV6; Q96BS7; Q96D33; Q96N85;
AC   Q9Y2J7;
DE   RecName: Full=WD repeat and FYVE domain-containing protein 3;
DE   AltName: Full=Autophagy-linked FYVE protein;
DE            Short=Alfy;
GN   Name=WDFY3; Synonyms=KIAA0993;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.
DR   GO; GO:0003831; F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   WDFY4_HUMAN             Reviewed;        3184 AA.
AC   Q6ZS81; B9ZVP2; Q86WZ4; Q8N4A3; Q8TEN7; Q96BE1; Q9H7H8; Q9HCG5;
DE   RecName: Full=WD repeat- and FYVE domain-containing protein 4;
GN   Name=WDFY4; Synonyms=C10orf64, KIAA1607;
//
ID   WDHD1_HUMAN             Reviewed;        1129 AA.
AC   O75717; C9JW18; F6W0U7;
DE   RecName: Full=WD repeat and HMG-box DNA-binding protein 1;
DE   AltName: Full=Acidic nucleoplasmic DNA-binding protein 1;
DE            Short=And-1;
GN   Name=WDHD1; Synonyms=AND1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:Ensembl.
DR   GO; GO:0070829; P:heterochromatin maintenance; IEA:Ensembl.
DR   GO; GO:0033044; P:regulation of chromosome organization; IEA:Ensembl.
DR   GO; GO:0006396; P:RNA processing; IEA:Ensembl.
//
ID   WDR11_HUMAN             Reviewed;        1224 AA.
AC   Q9BZH6; Q5VWA1; Q9P2J6;
DE   RecName: Full=WD repeat-containing protein 11;
DE   AltName: Full=Bromodomain and WD repeat-containing protein 2;
DE   AltName: Full=WD repeat-containing protein 15;
GN   Name=WDR11; Synonyms=BRWD2, KIAA1351, WDR15;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   WDR12_HUMAN             Reviewed;         423 AA.
AC   Q9GZL7; B3KPA9; Q96HU0; Q9NV80; Q9NYI8;
DE   RecName: Full=Ribosome biogenesis protein WDR12;
DE   AltName: Full=WD repeat-containing protein 12;
GN   Name=WDR12;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:UniProtKB.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:UniProtKB.
DR   GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IC:UniProtKB.
//
ID   WDR13_HUMAN             Reviewed;         485 AA.
AC   Q9H1Z4; Q06DW8; Q06DX0; Q06DX1; Q9BUL7; Q9NWW4;
DE   RecName: Full=WD repeat-containing protein 13;
GN   Name=WDR13;
//
ID   WDR16_HUMAN             Reviewed;         620 AA.
AC   Q8N1V2; B2RDU7; Q5DX23; Q8TC73; Q8TCI3;
DE   RecName: Full=WD repeat-containing protein 16;
DE   AltName: Full=WD40-repeat protein up-regulated in HCC;
GN   Name=WDR16; Synonyms=WDRPUH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   WDR17_HUMAN             Reviewed;        1322 AA.
AC   Q8IZU2; E7EQX0; Q0QD35;
DE   RecName: Full=WD repeat-containing protein 17;
GN   Name=WDR17;
//
ID   WDR18_HUMAN             Reviewed;         432 AA.
AC   Q9BV38; O60390; Q9BWR2;
DE   RecName: Full=WD repeat-containing protein 18;
GN   Name=WDR18;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   WDR19_HUMAN             Reviewed;        1342 AA.
AC   Q8NEZ3; B5MEF2; Q8N5B4; Q9H5S0; Q9HCD4;
DE   RecName: Full=WD repeat-containing protein 19;
GN   Name=WDR19; Synonyms=KIAA1638;
DR   GO; GO:0060830; P:ciliary receptor clustering involved in smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0042384; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0055123; P:digestive system development; IEA:Ensembl.
DR   GO; GO:0042471; P:ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0031076; P:embryonic camera-type eye development; IEA:Ensembl.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0030326; P:embryonic limb morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0061055; P:myotome development; IEA:Ensembl.
DR   GO; GO:0050877; P:neurological system process; IEA:Ensembl.
DR   GO; GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IEA:Ensembl.
//
ID   WDR1_HUMAN              Reviewed;         606 AA.
AC   O75083; A8K6E9; A8MPU4; O75313; Q8N6E5; Q9UG05; Q9UG78; Q9UQE0;
DE   RecName: Full=WD repeat-containing protein 1;
DE   AltName: Full=Actin-interacting protein 1;
DE            Short=AIP1;
DE   AltName: Full=NORI-1;
GN   Name=WDR1;
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030168; P:platelet activation; TAS:Reactome.
DR   GO; GO:0002576; P:platelet degranulation; TAS:Reactome.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
//
ID   WDR20_HUMAN             Reviewed;         569 AA.
AC   Q8TBZ3; B4DN18; E7EUY8; F8W9S4; G3V2F8; G3V5R0; H0YJJ1; Q86TU2;
AC   Q8NCN7; Q8WXX2; Q9UF86;
DE   RecName: Full=WD repeat-containing protein 20;
DE   AltName: Full=Protein DMR;
GN   Name=WDR20;
//
ID   WDR24_HUMAN             Reviewed;         920 AA.
AC   Q96S15; A2IDB8; D3DU59; Q96GC7; Q9H0B7;
DE   RecName: Full=WD repeat-containing protein 24;
GN   Name=WDR24; Synonyms=C16orf21; ORFNames=JFP7;
//
ID   WDR25_HUMAN             Reviewed;         544 AA.
AC   Q64LD2; A8K7E5; Q6NVV6; Q86TQ4; Q9BTK5;
DE   RecName: Full=WD repeat-containing protein 25;
GN   Name=WDR25;
//
ID   WDR26_HUMAN             Reviewed;         661 AA.
AC   Q9H7D7; A0MNN3; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2;
DE   RecName: Full=WD repeat-containing protein 26;
DE   AltName: Full=CUL4- and DDB1-associated WDR protein 2;
DE   AltName: Full=Myocardial ischemic preconditioning up-regulated protein 2;
GN   Name=WDR26; Synonyms=CDW2, MIP2; ORFNames=PRO0852;
//
ID   WDR27_HUMAN             Reviewed;         827 AA.
AC   A2RRH5; A5PLM8; C9JGV0; Q5T066;
DE   RecName: Full=WD repeat-containing protein 27;
GN   Name=WDR27;
//
ID   WDR31_HUMAN             Reviewed;         367 AA.
AC   Q8NA23; Q5W0T9; Q96EG8;
DE   RecName: Full=WD repeat-containing protein 31;
GN   Name=WDR31;
//
ID   WDR34_HUMAN             Reviewed;         536 AA.
AC   Q96EX3; Q5VXV4; Q9BV46;
DE   RecName: Full=WD repeat-containing protein 34;
GN   Name=WDR34;
//
ID   WDR33_HUMAN             Reviewed;        1336 AA.
AC   Q9C0J8; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9NUL1;
DE   RecName: Full=pre-mRNA 3' end processing protein WDR33;
DE   AltName: Full=WD repeat-containing protein 33;
DE   AltName: Full=WD repeat-containing protein WDC146;
GN   Name=WDR33; Synonyms=WDC146;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006301; P:postreplication repair; NAS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; NAS:UniProtKB.
//
ID   WDR35_HUMAN             Reviewed;        1181 AA.
AC   Q9P2L0; B3KVI5; Q4ZG01; Q8NE11;
DE   RecName: Full=WD repeat-containing protein 35;
DE   AltName: Full=Intraflagellar transport protein 121 homolog;
GN   Name=WDR35; Synonyms=IFT121, KIAA1336;
DR   GO; GO:0042384; P:cilium assembly; IMP:UniProtKB.
//
ID   WDR36_HUMAN             Reviewed;         951 AA.
AC   Q8NI36; A2RUS4; Q68E02; Q8N1Q2;
DE   RecName: Full=WD repeat-containing protein 36;
DE   AltName: Full=T-cell activation WD repeat-containing protein;
DE            Short=TA-WDRP;
GN   Name=WDR36;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0030516; P:regulation of axon extension; IEA:Ensembl.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0001895; P:retina homeostasis; IEA:Ensembl.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   WDR37_HUMAN             Reviewed;         494 AA.
AC   Q9Y2I8; A8K976; D3DRQ7; Q5SW03; Q8WVG2; Q9NTJ6;
DE   RecName: Full=WD repeat-containing protein 37;
GN   Name=WDR37; Synonyms=KIAA0982;
//
ID   WDR38_HUMAN             Reviewed;         314 AA.
AC   Q5JTN6; A0PK24;
DE   RecName: Full=WD repeat-containing protein 38;
GN   Name=WDR38;
//
ID   WDR3_HUMAN              Reviewed;         943 AA.
AC   Q9UNX4;
DE   RecName: Full=WD repeat-containing protein 3;
GN   Name=WDR3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   WDR41_HUMAN             Reviewed;         459 AA.
AC   Q9HAD4; B4DT55; Q7Z792; Q8IWG3; Q8IXA9; Q8NDA7; Q9NV62;
DE   RecName: Full=WD repeat-containing protein 41;
GN   Name=WDR41; ORFNames=MSTP048;
//
ID   WDR43_HUMAN             Reviewed;         677 AA.
AC   Q15061; Q15395; Q92577;
DE   RecName: Full=WD repeat-containing protein 43;
GN   Name=WDR43; Synonyms=KIAA0007, UTP5;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   WDR44_HUMAN             Reviewed;         913 AA.
AC   Q5JSH3; B4DSE9; F8W913; Q0JS52; Q0JTF3; Q5JSH2; Q6ZSC1; Q7Z365;
AC   Q7Z3P6; Q8NAU8; Q8NHU5; Q9NUV4;
DE   RecName: Full=WD repeat-containing protein 44;
DE   AltName: Full=Rabphilin-11;
GN   Name=WDR44;
//
ID   WDR46_HUMAN             Reviewed;         610 AA.
AC   O15213; A6NDP5; Q5HYZ0; Q5STK5; Q5STR3;
DE   RecName: Full=WD repeat-containing protein 46;
DE   AltName: Full=WD repeat-containing protein BING4;
GN   Name=WDR46; Synonyms=BING4, C6orf11; ORFNames=FP221;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   WDR47_HUMAN             Reviewed;         919 AA.
AC   O94967; A8MX09; Q5TYV7; Q5TYV8; Q5TYV9; Q8IXT7; Q8IYU9;
DE   RecName: Full=WD repeat-containing protein 47;
DE   AltName: Full=Neuronal enriched MAP interacting protein;
DE            Short=Nemitin;
GN   Name=WDR47; Synonyms=KIAA0893;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   WDR48_HUMAN             Reviewed;         677 AA.
AC   Q8TAF3; B4DM86; B4DQI2; B4DY84; Q63HJ2; Q658Y1; Q8N3Z1; Q9NSK8;
AC   Q9P279;
DE   RecName: Full=WD repeat-containing protein 48;
DE   AltName: Full=USP1-associated factor 1;
DE   AltName: Full=WD repeat endosomal protein;
DE   AltName: Full=p80;
GN   Name=WDR48; Synonyms=KIAA1449, UAF1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016579; P:protein deubiquitination; IDA:UniProtKB.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   WDR49_HUMAN             Reviewed;         697 AA.
AC   Q8IV35; Q8N297;
DE   RecName: Full=WD repeat-containing protein 49;
GN   Name=WDR49;
//
ID   WDR4_HUMAN              Reviewed;         412 AA.
AC   P57081; A8KA58; B2RCA3; B4DNQ7; D3DSK3; Q9BVM5; Q9HCR3;
DE   RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4;
DE   AltName: Full=WD repeat-containing protein 4;
GN   Name=WDR4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0036265; P:RNA (guanine-N7)-methylation; IEA:InterPro.
DR   GO; GO:0030488; P:tRNA methylation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006400; P:tRNA modification; IDA:UniProtKB.
//
ID   WDR52_HUMAN             Reviewed;         982 AA.
AC   Q96MT7;
DE   RecName: Full=WD repeat-containing protein 52;
GN   Name=WDR52;
//
ID   WDR53_HUMAN             Reviewed;         358 AA.
AC   Q7Z5U6; A0MNP1;
DE   RecName: Full=WD repeat-containing protein 53;
GN   Name=WDR53;
//
ID   WDR54_HUMAN             Reviewed;         334 AA.
AC   Q9H977; D6W5I3; Q53H85; Q86V45;
DE   RecName: Full=WD repeat-containing protein 54;
GN   Name=WDR54;
//
ID   WDR55_HUMAN             Reviewed;         383 AA.
AC   Q9H6Y2; Q9NXK4;
DE   RecName: Full=WD repeat-containing protein 55;
GN   Name=WDR55;
DR   GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
//
ID   WDR59_HUMAN             Reviewed;         974 AA.
AC   Q6PJI9; B3KRC3; Q71RE7; Q96PW5; Q9BSW6; Q9HA43;
DE   RecName: Full=WD repeat-containing protein 59;
GN   Name=WDR59; Synonyms=KIAA1923; ORFNames=FP977;
//
ID   WDR5B_HUMAN             Reviewed;         330 AA.
AC   Q86VZ2; B2RCM9; Q9NUL4;
DE   RecName: Full=WD repeat-containing protein 5B;
GN   Name=WDR5B;
//
ID   WDR5_HUMAN              Reviewed;         334 AA.
AC   P61964; Q91VA5; Q9NWX7; Q9UGP9;
DE   RecName: Full=WD repeat-containing protein 5;
DE   AltName: Full=BMP2-induced 3-kb gene protein;
GN   Name=WDR5; Synonyms=BIG3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
DR   GO; GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.
DR   GO; GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.
DR   GO; GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001501; P:skeletal system development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   WDR60_HUMAN             Reviewed;        1066 AA.
AC   Q8WVS4; Q9NW58;
DE   RecName: Full=WD repeat-containing protein 60;
GN   Name=WDR60;
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
//
ID   WDR61_HUMAN             Reviewed;         305 AA.
AC   Q9GZS3; D3DW84; Q6IA22; Q7Z4X4;
DE   RecName: Full=WD repeat-containing protein 61;
DE   AltName: Full=Meiotic recombination REC14 protein homolog;
DE   AltName: Full=SKI8 homolog;
DE            Short=Ski8;
DE   Contains:
DE     RecName: Full=WD repeat-containing protein 61, N-terminally processed;
GN   Name=WDR61;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.
DR   GO; GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.
DR   GO; GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.
DR   GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   WDR62_HUMAN             Reviewed;        1518 AA.
AC   O43379; Q63HP9; Q659D7; Q8NBF7; Q96AD9;
DE   RecName: Full=WD repeat-containing protein 62;
GN   Name=WDR62; Synonyms=C19orf14;
DR   GO; GO:0021987; P:cerebral cortex development; IMP:UniProtKB.
DR   GO; GO:0022008; P:neurogenesis; IMP:UniProtKB.
//
ID   WDR64_HUMAN             Reviewed;        1081 AA.
AC   B1ANS9; B1ANT0; Q7Z573; Q96LY9;
DE   RecName: Full=WD repeat-containing protein 64;
GN   Name=WDR64;
//
ID   WDR63_HUMAN             Reviewed;         891 AA.
AC   Q8IWG1; A8K988; Q96L72; Q96NU4;
DE   RecName: Full=WD repeat-containing protein 63;
DE   AltName: Full=Testis development protein NYD-SP29;
GN   Name=WDR63;
//
ID   WDR65_HUMAN             Reviewed;        1250 AA.
AC   Q96MR6; A6NKQ3; Q17RI9; Q5TAI0;
DE   RecName: Full=WD repeat-containing protein 65;
GN   Name=WDR65;
//
ID   WDR66_HUMAN             Reviewed;        1149 AA.
AC   Q8TBY9; C9J1W2; Q8IYA3; Q8N898; Q8NDE7;
DE   RecName: Full=WD repeat-containing protein 66;
GN   Name=WDR66;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
//
ID   WDR6_HUMAN              Reviewed;        1121 AA.
AC   Q9NNW5; B4DHK2; Q3MIT1; Q9UF63;
DE   RecName: Full=WD repeat-containing protein 6;
GN   Name=WDR6;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007050; P:cell cycle arrest; IDA:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:BHF-UCL.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
//
ID   WDR70_HUMAN             Reviewed;         654 AA.
AC   Q9NW82; Q9H053;
DE   RecName: Full=WD repeat-containing protein 70;
GN   Name=WDR70;
//
ID   WDR72_HUMAN             Reviewed;        1102 AA.
AC   Q3MJ13; Q7Z3I3; Q8N8X2;
DE   RecName: Full=WD repeat-containing protein 72;
GN   Name=WDR72;
//
ID   WDR73_HUMAN             Reviewed;         378 AA.
AC   Q6P4I2; Q96JZ1; Q9P0B7;
DE   RecName: Full=WD repeat-containing protein 73;
GN   Name=WDR73; ORFNames=HSPC264;
//
ID   WDR74_HUMAN             Reviewed;         385 AA.
AC   Q6RFH5; A8K8G5; Q9BRC9; Q9H6X8; Q9NVY2;
DE   RecName: Full=WD repeat-containing protein 74;
DE   AltName: Full=NOP seven-associated protein 1;
GN   Name=WDR74; Synonyms=NSA1;
DR   GO; GO:0001825; P:blastocyst formation; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; IEA:Ensembl.
//
ID   WDR75_HUMAN             Reviewed;         830 AA.
AC   Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2;
DE   RecName: Full=WD repeat-containing protein 75;
GN   Name=WDR75; Synonyms=UTP17;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   WDR76_HUMAN             Reviewed;         626 AA.
AC   Q9H967; A0MNP5; Q05CI4;
DE   RecName: Full=WD repeat-containing protein 76;
GN   Name=WDR76;
//
ID   WDR78_HUMAN             Reviewed;         848 AA.
AC   Q5VTH9; A8K9W5; B5MDT3; H7BY80; Q5VTI0; Q8N5G5; Q9H5R9; Q9UF44;
DE   RecName: Full=WD repeat-containing protein 78;
GN   Name=WDR78;
//
ID   WDR7_HUMAN              Reviewed;        1490 AA.
AC   Q9Y4E6; A7E2C8; Q86UX5; Q86VP2; Q96PS7;
DE   RecName: Full=WD repeat-containing protein 7;
DE   AltName: Full=Rabconnectin-3 beta;
DE   AltName: Full=TGF-beta resistance-associated protein TRAG;
GN   Name=WDR7; Synonyms=KIAA0541, TRAG;
//
ID   WDR81_HUMAN             Reviewed;        1941 AA.
AC   Q562E7; B3KW16; B3KXU1; B7Z579; E9PHG7; Q24JP6; Q8N277; Q8N3F3;
AC   Q8TEL1;
DE   RecName: Full=WD repeat-containing protein 81;
GN   Name=WDR81;
DR   GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   WDR82_HUMAN             Reviewed;         313 AA.
AC   Q6UXN9; A8K5R5; Q8TEB2;
DE   RecName: Full=WD repeat-containing protein 82;
DE   AltName: Full=Protein TMEM113;
DE   AltName: Full=Swd2;
GN   Name=WDR82; Synonyms=TMEM113, WDR82A; ORFNames=UNQ9342/PRO34047;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.
//
ID   WDR83_HUMAN             Reviewed;         315 AA.
AC   Q9BRX9; B2RAF1; Q53FT6;
DE   RecName: Full=WD repeat domain-containing protein 83;
DE   AltName: Full=Mitogen-activated protein kinase organizer 1;
DE            Short=MAPK organizer 1;
GN   Name=WDR83; Synonyms=MORG1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IDA:UniProtKB.
DR   GO; GO:0000375; P:RNA splicing, via transesterification reactions; IDA:UniProtKB.
//
ID   WDR86_HUMAN             Reviewed;         376 AA.
AC   Q86TI4; B4DJF1; C9JXE3; Q3KNT1; Q6ZUS8;
DE   RecName: Full=WD repeat-containing protein 86;
GN   Name=WDR86;
//
ID   WDR87_HUMAN             Reviewed;        2873 AA.
AC   Q6ZQQ6; Q9BWV9;
DE   RecName: Full=WD repeat-containing protein 87;
DE   AltName: Full=Testis development protein NYD-SP11;
GN   Name=WDR87;
//
ID   WDR88_HUMAN             Reviewed;         472 AA.
AC   Q6ZMY6; Q8NEF8;
DE   RecName: Full=WD repeat-containing protein 88;
DE   AltName: Full=PQQ repeat and WD repeat-containing protein;
GN   Name=WDR88; Synonyms=PQWD;
//
ID   WDR89_HUMAN             Reviewed;         387 AA.
AC   Q96FK6;
DE   RecName: Full=WD repeat-containing protein 89;
GN   Name=WDR89; Synonyms=C14orf150; ORFNames=MSTP050;
//
ID   WDR90_HUMAN             Reviewed;        1748 AA.
AC   Q96KV7; Q0VA87; Q0VA88; Q6P048; Q6ZMS1; Q6ZTH1; Q8N202; Q8N221;
AC   Q8NBB8; Q96PW4; Q96S18;
DE   RecName: Full=WD repeat-containing protein 90;
GN   Name=WDR90;
GN   Synonyms=C16orf15, C16orf16, C16orf17, C16orf18, C16orf19, KIAA1924;
//
ID   WDR91_HUMAN             Reviewed;         747 AA.
AC   A4D1P6; A6NK54; C9JMI4; Q6FI65; Q6MZQ1; Q6P4I1; Q96AE5; Q96G63;
AC   Q9H062; Q9H9B6; Q9NVG7; Q9NZY6;
DE   RecName: Full=WD repeat-containing protein 91;
GN   Name=WDR91; ORFNames=HSPC049;
//
ID   WDR92_HUMAN             Reviewed;         357 AA.
AC   Q96MX6; Q96CR6;
DE   RecName: Full=WD repeat-containing protein 92;
DE   AltName: Full=WD repeat-containing protein Monad;
GN   Name=WDR92;
DR   GO; GO:0035064; F:methylated histone binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0034968; P:histone lysine methylation; IDA:UniProtKB.
//
ID   WDR93_HUMAN             Reviewed;         686 AA.
AC   Q6P2C0; Q8N7Y8; Q9NP89;
DE   RecName: Full=WD repeat-containing protein 93;
GN   Name=WDR93;
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:InterPro.
//
ID   WDR96_HUMAN             Reviewed;        1665 AA.
AC   Q8NDM7; Q8N9Z8; Q8NE17; Q9H085; Q9H5W3;
DE   RecName: Full=WD repeat-containing protein 96;
GN   Name=WDR96; Synonyms=C10orf79;
//
ID   WDTC1_HUMAN             Reviewed;         677 AA.
AC   Q8N5D0; D3DPL5; Q5SSC5; Q9NV87; Q9UPW4;
DE   RecName: Full=WD and tetratricopeptide repeats protein 1;
GN   Name=WDTC1; Synonyms=KIAA1037;
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:DFLAT.
DR   GO; GO:0055082; P:cellular chemical homeostasis; IEA:Ensembl.
DR   GO; GO:0032869; P:cellular response to insulin stimulus; IEA:Ensembl.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0008361; P:regulation of cell size; IEA:Ensembl.
//
ID   WEE1_HUMAN              Reviewed;         646 AA.
AC   P30291; B3KVE1; D3DQV0;
DE   RecName: Full=Wee1-like protein kinase;
DE            Short=WEE1hu;
DE            EC=2.7.10.2;
DE   AltName: Full=Wee1A kinase;
GN   Name=WEE1;
DR   GuidetoPHARMACOLOGY; 2278; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0051726; P:regulation of cell cycle; TAS:Reactome.
//
ID   WEE2_HUMAN              Reviewed;         567 AA.
AC   P0C1S8;
DE   RecName: Full=Wee1-like protein kinase 2;
DE            EC=2.7.10.2;
DE   AltName: Full=Wee1-like protein kinase 1B;
DE   AltName: Full=Wee1B kinase;
GN   Name=WEE2; Synonyms=WEE1B;
DR   GuidetoPHARMACOLOGY; 2279; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0007143; P:female meiotic division; ISS:UniProtKB.
DR   GO; GO:0035038; P:female pronucleus assembly; ISS:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:InterPro.
DR   GO; GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:Ensembl.
DR   GO; GO:1900194; P:negative regulation of oocyte maturation; ISS:UniProtKB.
DR   GO; GO:0060631; P:regulation of meiosis I; ISS:UniProtKB.
//
ID   WF10A_HUMAN             Reviewed;          79 AA.
AC   Q9H1F0; A2RRE9; Q5TGZ7;
DE   RecName: Full=WAP four-disulfide core domain protein 10A;
DE   AltName: Full=Putative protease inhibitor WAP10A;
DE   Flags: Precursor;
GN   Name=WFDC10A; Synonyms=C20orf146, WAP10;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WF10B_HUMAN             Reviewed;          73 AA.
AC   Q8IUB3; A6PVD7; Q0VAG0; Q0VAG1; Q5TGZ5; Q8IUB4;
DE   RecName: Full=Protein WFDC10B;
DE   Flags: Precursor;
GN   Name=WFDC10B; Synonyms=WAP12;
DR   GO; GO:0030414; F:peptidase inhibitor activity; IEA:InterPro.
//
ID   WFD11_HUMAN             Reviewed;          87 AA.
AC   Q8NEX6; E1P624; Q5TGZ6;
DE   RecName: Full=Protein WFDC11;
DE   Flags: Precursor;
GN   Name=WFDC11; Synonyms=WAP11;
//
ID   WFD12_HUMAN             Reviewed;         111 AA.
AC   Q8WWY7; Q5H980; Q9BR31;
DE   RecName: Full=WAP four-disulfide core domain protein 12;
DE   AltName: Full=Putative protease inhibitor WAP12;
DE   AltName: Full=Whey acidic protein 2;
DE   Flags: Precursor;
GN   Name=WFDC12; Synonyms=C20orf122, WAP2; ORFNames=UNQ544/PRO844;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; NAS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; ISS:UniProtKB.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; NAS:GOC.
//
ID   WFD13_HUMAN             Reviewed;          93 AA.
AC   Q8IUB5; Q5TEU7; Q8WWK7;
DE   RecName: Full=WAP four-disulfide core domain protein 13;
DE   Flags: Precursor;
GN   Name=WFDC13; Synonyms=C20orf138, WAP13;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WFDC1_HUMAN             Reviewed;         220 AA.
AC   Q9HC57; D3DUL7; Q8NC27; Q9HAU1;
DE   RecName: Full=WAP four-disulfide core domain protein 1;
DE   AltName: Full=Prostate stromal protein ps20;
DE   AltName: Full=ps20 growth inhibitor;
DE   Flags: Precursor;
GN   Name=WFDC1; Synonyms=PS20;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
//
ID   WFDC2_HUMAN             Reviewed;         124 AA.
AC   Q14508; A2A2A5; A2A2A6; A6PVD5; Q6IB27; Q8WXV9; Q8WXW0; Q8WXW1;
AC   Q8WXW2; Q96KJ1;
DE   RecName: Full=WAP four-disulfide core domain protein 2;
DE   AltName: Full=Epididymal secretory protein E4;
DE   AltName: Full=Major epididymis-specific protein E4;
DE   AltName: Full=Putative protease inhibitor WAP5;
DE   Flags: Precursor;
GN   Name=WFDC2; Synonyms=HE4, WAP5;
DR   GO; GO:0019828; F:aspartic-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004866; F:endopeptidase inhibitor activity; TAS:ProtInc.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; TAS:GOC.
DR   GO; GO:0006508; P:proteolysis; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
//
ID   WFDC3_HUMAN             Reviewed;         231 AA.
AC   Q8IUB2; A6PVF2; Q0P6A5; Q3T1C5; Q8TC52; Q9BQP3; Q9BQP4;
DE   RecName: Full=WAP four-disulfide core domain protein 3;
DE   AltName: Full=Putative protease inhibitor WAP14;
DE   Flags: Precursor;
GN   Name=WFDC3; Synonyms=WAP14;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WFDC5_HUMAN             Reviewed;         224 AA.
AC   Q8TCV5; Q5H981; Q6UWE4;
DE   RecName: Full=WAP four-disulfide core domain protein 5;
DE   AltName: Full=Putative protease inhibitor WAP1;
DE   AltName: Full=p53-responsive gene 5 protein;
DE   Flags: Precursor;
GN   Name=WFDC5; Synonyms=PRG5, WAP1; ORFNames=UNQ3036/PRO9842;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WFDC6_HUMAN             Reviewed;         131 AA.
AC   Q9BQY6; Q3MJ23; Q5JYQ4; Q8NFV6;
DE   RecName: Full=WAP four-disulfide core domain protein 6;
DE   AltName: Full=Putative protease inhibitor WAP6;
DE   Flags: Precursor;
GN   Name=WFDC6; Synonyms=C20orf171, WAP6;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WFDC8_HUMAN             Reviewed;         241 AA.
AC   Q8IUA0; E1P623; Q5TDV2; Q96A34;
DE   RecName: Full=WAP four-disulfide core domain protein 8;
DE   AltName: Full=Putative protease inhibitor WAP8;
DE   Flags: Precursor;
GN   Name=WFDC8; Synonyms=C20orf170, WAP8;
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WFDC9_HUMAN             Reviewed;          89 AA.
AC   Q8NEX5; Q3MIX6; Q5TGZ8;
DE   RecName: Full=Protein WFDC9;
DE   Flags: Precursor;
GN   Name=WFDC9; Synonyms=WAP9;
//
ID   WFKN1_HUMAN             Reviewed;         548 AA.
AC   Q96NZ8; Q7LDW0; Q8NBQ1; Q96S20;
DE   RecName: Full=WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1;
DE   AltName: Full=Growth and differentiation factor-associated serum protein 2;
DE            Short=GASP-2;
DE            Short=hGASP-2;
DE   AltName: Full=WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein;
DE   Flags: Precursor;
GN   Name=WFIKKN1; Synonyms=C16orf12, GASP2, WFIKKN; ORFNames=PSEC0040;
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
//
ID   WFKN2_HUMAN             Reviewed;         576 AA.
AC   Q8TEU8; Q6UXZ9;
DE   RecName: Full=WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2;
DE   AltName: Full=Growth and differentiation factor-associated serum protein 1;
DE            Short=GASP-1;
DE            Short=hGASP-1;
DE   AltName: Full=WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein;
DE   AltName: Full=WFIKKN-related protein;
DE   Flags: Precursor;
GN   Name=WFIKKN2; Synonyms=GASP1, WFIKKNRP; ORFNames=UNQ9235/PRO31996;
DR   GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
//
ID   WFS1_HUMAN              Reviewed;         890 AA.
AC   O76024; B2R797; D3DVT1; Q8N6I3; Q9UNW6;
DE   RecName: Full=Wolframin;
GN   Name=WFS1;
DR   GO; GO:0033613; F:activating transcription factor binding; ISS:BHF-UCL.
DR   GO; GO:0051117; F:ATPase binding; IPI:BHF-UCL.
DR   GO; GO:0005215; F:transporter activity; ISS:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; ISS:BHF-UCL.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0055074; P:calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IDA:BHF-UCL.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:BHF-UCL.
DR   GO; GO:0006983; P:ER overload response; TAS:BHF-UCL.
DR   GO; GO:0030433; P:ER-associated ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.
DR   GO; GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.
DR   GO; GO:0001822; P:kidney development; IMP:BHF-UCL.
DR   GO; GO:1902236; P:negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; ISS:BHF-UCL.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0043069; P:negative regulation of programmed cell death; IMP:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:2000675; P:negative regulation of type B pancreatic cell apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0050877; P:neurological system process; IMP:BHF-UCL.
DR   GO; GO:0042048; P:olfactory behavior; IEA:Ensembl.
DR   GO; GO:0070845; P:polyubiquitinated misfolded protein transport; ISS:BHF-UCL.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IDA:BHF-UCL.
DR   GO; GO:0045927; P:positive regulation of growth; ISS:BHF-UCL.
DR   GO; GO:0051247; P:positive regulation of protein metabolic process; IDA:BHF-UCL.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; ISS:BHF-UCL.
DR   GO; GO:0045862; P:positive regulation of proteolysis; ISS:BHF-UCL.
DR   GO; GO:0022417; P:protein maturation by protein folding; IC:BHF-UCL.
DR   GO; GO:0050821; P:protein stabilization; ISS:BHF-UCL.
DR   GO; GO:0003091; P:renal water homeostasis; IMP:BHF-UCL.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IDA:BHF-UCL.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:BHF-UCL.
DR   GO; GO:0007601; P:visual perception; IMP:BHF-UCL.
//
ID   WHAL1_HUMAN             Reviewed;         153 AA.
AC   Q1A5X7; Q1A5X8; Q52M16; Q52M18;
DE   RecName: Full=Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1;
DE   AltName: Full=WAS protein homolog associated with actin, Golgi membranes and microtubules pseudogene 3;
DE   AltName: Full=WAS protein homology region 2 domain-containing protein 1-like protein 1;
DE            Short=WH2 domain-containing protein 1-like protein 1;
DE            Short=WHDC1-like protein 1;
GN   Name=WHAMMP3; Synonyms=WHAMML1, WHDC1L1;
//
ID   WHAMM_HUMAN             Reviewed;         809 AA.
AC   Q8TF30; Q8N1J9;
DE   RecName: Full=WASP homolog-associated protein with actin, membranes and microtubules;
DE   AltName: Full=WAS protein homology region 2 domain-containing protein 1;
DE            Short=WH2 domain-containing protein 1;
GN   Name=WHAMM; Synonyms=KIAA1971, WHDC1;
//
ID   WHRN_HUMAN              Reviewed;         907 AA.
AC   Q9P202; A5PKU1; A5PKZ9; Q5TAU9; Q5TAV0; Q5TAV1; Q5TAV2; Q96MZ9;
AC   Q9H9F4; Q9UFZ3;
DE   RecName: Full=Whirlin;
DE   AltName: Full=Autosomal recessive deafness type 31 protein;
GN   Name=DFNB31; Synonyms=KIAA1526, WHRN;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0060122; P:inner ear receptor stereocilium organization; ISS:UniProtKB.
DR   GO; GO:0001895; P:retina homeostasis; IMP:HGNC.
DR   GO; GO:0050953; P:sensory perception of light stimulus; IMP:HGNC.
DR   GO; GO:0007605; P:sensory perception of sound; IMP:HGNC.
//
ID   WIBG_HUMAN              Reviewed;         204 AA.
AC   Q9BRP8; B6ZDM5; Q8IXJ8; Q8N8E7;
DE   RecName: Full=Partner of Y14 and mago;
DE   AltName: Full=Protein wibg homolog;
GN   Name=WIBG; Synonyms=PYM;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043022; F:ribosome binding; IDA:UniProtKB.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IDA:UniProtKB.
DR   GO; GO:0045727; P:positive regulation of translation; IDA:UniProtKB.
//
ID   WIF1_HUMAN              Reviewed;         379 AA.
AC   Q9Y5W5; Q6UXI1; Q8WVG4;
DE   RecName: Full=Wnt inhibitory factor 1;
DE            Short=WIF-1;
DE   Flags: Precursor;
GN   Name=WIF1; ORFNames=UNQ191/PRO217;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; NAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   WIPF1_HUMAN             Reviewed;         503 AA.
AC   O43516; B8ZZM1; D3DPE4; Q15220; Q53TA9; Q6MZU9; Q9BU37; Q9UNP1;
DE   RecName: Full=WAS/WASL-interacting protein family member 1;
DE   AltName: Full=Protein PRPL-2;
DE   AltName: Full=Wiskott-Aldrich syndrome protein-interacting protein;
DE            Short=WASP-interacting protein;
GN   Name=WIPF1; Synonyms=WASPIP, WIP;
DR   GO; GO:0003779; F:actin binding; TAS:ProtInc.
DR   GO; GO:0005522; F:profilin binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0030048; P:actin filament-based movement; IEA:Ensembl.
DR   GO; GO:0008154; P:actin polymerization or depolymerization; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0051707; P:response to other organism; IEA:Ensembl.
//
ID   WIPF2_HUMAN             Reviewed;         440 AA.
AC   Q8TF74; A8K0L3; Q658J8; Q71RE1; Q8TE44;
DE   RecName: Full=WAS/WASL-interacting protein family member 2;
DE   AltName: Full=WASP-interacting protein-related protein;
DE   AltName: Full=WIP- and CR16-homologous protein;
DE   AltName: Full=WIP-related protein;
GN   Name=WIPF2; Synonyms=WICH, WIRE; ORFNames=PP10631;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
//
ID   WIPF3_HUMAN             Reviewed;         483 AA.
AC   A6NGB9; B8ZZV2;
DE   RecName: Full=WAS/WASL-interacting protein family member 3;
DE   AltName: Full=Corticosteroids and regional expression protein 16 homolog;
GN   Name=WIPF3; Synonyms=CR16;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
//
ID   WIPI1_HUMAN             Reviewed;         446 AA.
AC   Q5MNZ9; Q8IXM5; Q9NWF8;
DE   RecName: Full=WD repeat domain phosphoinositide-interacting protein 1;
DE            Short=WIPI-1;
DE   AltName: Full=Atg18 protein homolog;
DE   AltName: Full=WD40 repeat protein interacting with phosphoinositides of 49 kDa;
DE            Short=WIPI 49 kDa;
GN   Name=WIPI1; Synonyms=WIPI49;
DR   GO; GO:0050681; F:androgen receptor binding; IDA:UniProtKB.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; IDA:MGI.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IBA:RefGenome.
DR   GO; GO:0006914; P:autophagy; IEP:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0048203; P:vesicle targeting, trans-Golgi to endosome; IDA:UniProtKB.
//
ID   WIPI2_HUMAN             Reviewed;         454 AA.
AC   Q9Y4P8; B3KNC2; Q5MNZ8; Q6FI96; Q75L50; Q96IE4; Q9Y364;
DE   RecName: Full=WD repeat domain phosphoinositide-interacting protein 2;
DE            Short=WIPI-2;
DE   AltName: Full=WIPI49-like protein 2;
GN   Name=WIPI2; ORFNames=CGI-50;
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.
//
ID   WIPI3_HUMAN             Reviewed;         344 AA.
AC   Q5MNZ6; O95328; Q2MCP6; Q6IBN2;
DE   RecName: Full=WD repeat domain phosphoinositide-interacting protein 3;
DE            Short=WIPI-3;
DE   AltName: Full=WD repeat-containing protein 45-like;
DE            Short=WDR45-like protein;
DE   AltName: Full=WD repeat-containing protein 45B;
DE   AltName: Full=WIPI49-like protein;
GN   Name=WDR45B; Synonyms=WDR45L, WIPI3;
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:RefGenome.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IBA:RefGenome.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IBA:RefGenome.
//
ID   WIPI4_HUMAN             Reviewed;         360 AA.
AC   Q9Y484; A6NGH5; B7WPI2; Q5MNZ5; Q6IBS7; Q6NT94; Q96H03;
DE   RecName: Full=WD repeat domain phosphoinositide-interacting protein 4;
DE            Short=WIPI-4;
DE   AltName: Full=WD repeat-containing protein 45;
GN   Name=WDR45; Synonyms=WDRX1, WDRXI4, WIPI4; ORFNames=JM5;
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IBA:RefGenome.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IBA:RefGenome.
DR   GO; GO:0000045; P:autophagic vacuole assembly; IBA:RefGenome.
DR   GO; GO:0006914; P:autophagy; IMP:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
//
ID   WISP1_HUMAN             Reviewed;         367 AA.
AC   O95388; A8KAG6; E7EMM5; Q5JBS6; Q5JBS7; Q5JBS8; Q9HCS3;
DE   RecName: Full=WNT1-inducible-signaling pathway protein 1;
DE            Short=WISP-1;
DE   AltName: Full=CCN family member 4;
DE   AltName: Full=Wnt-1-induced secreted protein;
DE   Flags: Precursor;
GN   Name=WISP1; Synonyms=CCN4;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   WISP2_HUMAN             Reviewed;         250 AA.
AC   O76076; B2R9N4; E1P612;
DE   RecName: Full=WNT1-inducible-signaling pathway protein 2;
DE            Short=WISP-2;
DE   AltName: Full=CCN family member 5;
DE   AltName: Full=Connective tissue growth factor-like protein;
DE            Short=CTGF-L;
DE   AltName: Full=Connective tissue growth factor-related protein 58;
DE   Flags: Precursor;
GN   Name=WISP2; Synonyms=CCN5, CT58, CTGFL; ORFNames=UNQ228/PRO261;
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   WISP3_HUMAN             Reviewed;         354 AA.
AC   O95389; Q3KR29; Q5H8W4; Q6UXH6;
DE   RecName: Full=WNT1-inducible-signaling pathway protein 3;
DE            Short=WISP-3;
DE   AltName: Full=CCN family member 6;
DE   Flags: Precursor;
GN   Name=WISP3; Synonyms=CCN6; ORFNames=UNQ462/PRO790/PRO956;
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0001558; P:regulation of cell growth; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   WIT1_HUMAN              Reviewed;          92 AA.
AC   Q06250; Q4KMY0; Q96A27;
DE   RecName: Full=Putative Wilms tumor upstream neighbor 1 gene protein;
DE            Short=WIT-1;
DE   AltName: Full=Wilms tumor-associated antisense RNA;
GN   Name=WT1-AS; Synonyms=WIT1;
//
ID   WIZ_HUMAN               Reviewed;        1651 AA.
AC   O95785; B7ZM82; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5;
AC   Q96SQ6; Q9BUR8; Q9NPT1;
DE   RecName: Full=Protein Wiz;
DE   AltName: Full=Widely-interspaced zinc finger-containing protein;
DE   AltName: Full=Zinc finger protein 803;
GN   Name=WIZ; Synonyms=ZNF803;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0010571; P:positive regulation of nuclear cell cycle DNA replication; IMP:UniProt.
DR   GO; GO:0070208; P:protein heterotrimerization; IDA:UniProt.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProt.
//
ID   WLS_HUMAN               Reviewed;         541 AA.
AC   Q5T9L3; B2RNT2; Q5JRS7; Q7Z2Z9; Q8NC43;
DE   RecName: Full=Protein wntless homolog;
DE   AltName: Full=Integral membrane protein GPR177;
DE   AltName: Full=Protein evenness interrupted homolog;
DE            Short=EVI;
DE   AltName: Full=Putative NF-kappa-B-activating protein 373;
DE   Flags: Precursor;
GN   Name=WLS; Synonyms=C1orf139, GPR177; ORFNames=UNQ85/PRO18667;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004871; F:signal transducer activity; ISS:UniProtKB.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   WN10A_HUMAN             Reviewed;         417 AA.
AC   Q9GZT5; Q53S44; Q96TA7; Q9H7S8;
DE   RecName: Full=Protein Wnt-10a;
DE   Flags: Precursor;
GN   Name=WNT10A;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0048730; P:epidermis morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0001942; P:hair follicle development; IMP:BHF-UCL.
DR   GO; GO:0031069; P:hair follicle morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0014033; P:neural crest cell differentiation; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0042476; P:odontogenesis; IMP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0048733; P:sebaceous gland development; IMP:BHF-UCL.
DR   GO; GO:0043588; P:skin development; IMP:BHF-UCL.
DR   GO; GO:0043586; P:tongue development; IMP:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IBA:RefGenome.
//
ID   WN10B_HUMAN             Reviewed;         389 AA.
AC   O00744; B2R7A5; O00747; Q4VAJ5; Q8WZ97;
DE   RecName: Full=Protein Wnt-10b;
DE   AltName: Full=Protein Wnt-12;
DE   Flags: Precursor;
GN   Name=WNT10B; Synonyms=WNT12;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0048018; F:receptor agonist activity; IC:BHF-UCL.
DR   GO; GO:0060346; P:bone trabecula formation; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071320; P:cellular response to cAMP; IEA:Ensembl.
DR   GO; GO:0071464; P:cellular response to hydrostatic pressure; IEA:Ensembl.
DR   GO; GO:0071374; P:cellular response to parathyroid hormone stimulus; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0061196; P:fungiform papilla development; IEA:Ensembl.
DR   GO; GO:0000086; P:G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:Ensembl.
DR   GO; GO:0014835; P:myoblast differentiation involved in skeletal muscle regeneration; IEA:Ensembl.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0051885; P:positive regulation of anagen; IEA:Ensembl.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030858; P:positive regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0050821; P:protein stabilization; IDA:BHF-UCL.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0048641; P:regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0050909; P:sensory perception of taste; IEA:Ensembl.
DR   GO; GO:0048741; P:skeletal muscle fiber development; IEA:Ensembl.
DR   GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:UniProtKB.
//
ID   WNK1_HUMAN              Reviewed;        2382 AA.
AC   Q9H4A3; A1L4B0; C5HTZ5; C5HTZ6; C5HTZ7; H6WZW3; O15052; P54963;
AC   Q4VBX9; Q6IFS5; Q86WL5; Q8N673; Q96CZ6; Q9P1S9;
DE   RecName: Full=Serine/threonine-protein kinase WNK1;
DE            EC=2.7.11.1;
DE   AltName: Full=Erythrocyte 65 kDa protein;
DE            Short=p65;
DE   AltName: Full=Kinase deficient protein;
DE   AltName: Full=Protein kinase lysine-deficient 1;
DE   AltName: Full=Protein kinase with no lysine 1;
DE            Short=hWNK1;
GN   Name=WNK1; Synonyms=HSN2, KDP, KIAA0344, PRKWNK1;
DR   GO; GO:0005524; F:ATP binding; IDA:UniProtKB.
DR   GO; GO:0019869; F:chloride channel inhibitor activity; IDA:UniProt.
DR   GO; GO:0019902; F:phosphatase binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IDA:UniProtKB.
DR   GO; GO:0006811; P:ion transport; ISS:UniProtKB.
DR   GO; GO:0090188; P:negative regulation of pancreatic juice secretion; IEA:Ensembl.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
DR   GO; GO:0048666; P:neuron development; NAS:UniProtKB.
DR   GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0050794; P:regulation of cellular process; ISS:UniProtKB.
//
ID   WNK2_HUMAN              Reviewed;        2297 AA.
AC   Q9Y3S1; Q5VWF1; Q5VWF2; Q8IY36; Q9C0A3; Q9H3P4;
DE   RecName: Full=Serine/threonine-protein kinase WNK2;
DE            EC=2.7.11.1;
DE   AltName: Full=Antigen NY-CO-43;
DE   AltName: Full=Protein kinase lysine-deficient 2;
DE   AltName: Full=Protein kinase with no lysine 2;
DE   AltName: Full=Serologically defined colon cancer antigen 43;
GN   Name=WNK2; Synonyms=KIAA1760, PRKWNK2, SDCCAG43; ORFNames=P/OKcl.13;
DR   GuidetoPHARMACOLOGY; 2281; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.
DR   GO; GO:2000651; P:positive regulation of sodium ion transmembrane transporter activity; IMP:UniProtKB.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000021; P:regulation of ion homeostasis; IMP:UniProtKB.
//
ID   WNK3_HUMAN              Reviewed;        1800 AA.
AC   Q9BYP7; B1AKG2; Q5JRC1; Q6JP76; Q8TCX6; Q9HCK6;
DE   RecName: Full=Serine/threonine-protein kinase WNK3;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase lysine-deficient 3;
DE   AltName: Full=Protein kinase with no lysine 3;
GN   Name=WNK3; Synonyms=KIAA1566, PRKWNK3;
DR   GuidetoPHARMACOLOGY; 2282; -.
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0019869; F:chloride channel inhibitor activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004672; F:protein kinase activity; IDA:BHF-UCL.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IMP:UniProtKB.
DR   GO; GO:0090004; P:positive regulation of establishment of protein localization to plasma membrane; IDA:BHF-UCL.
DR   GO; GO:0032414; P:positive regulation of ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:UniProtKB.
DR   GO; GO:2000688; P:positive regulation of rubidium ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:2000682; P:positive regulation of rubidium ion transport; IDA:UniProtKB.
DR   GO; GO:2000651; P:positive regulation of sodium ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0010765; P:positive regulation of sodium ion transport; IDA:BHF-UCL.
DR   GO; GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:2000021; P:regulation of ion homeostasis; IMP:UniProtKB.
//
ID   WNK4_HUMAN              Reviewed;        1243 AA.
AC   Q96J92; Q8N8X3; Q8N8Z2; Q96DT8; Q9BYS5;
DE   RecName: Full=Serine/threonine-protein kinase WNK4;
DE            EC=2.7.11.1;
DE   AltName: Full=Protein kinase lysine-deficient 4;
DE   AltName: Full=Protein kinase with no lysine 4;
GN   Name=WNK4; Synonyms=PRKWNK4;
DR   GO; GO:0005524; F:ATP binding; ISS:UniProtKB.
DR   GO; GO:0019869; F:chloride channel inhibitor activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
DR   GO; GO:0006821; P:chloride transport; IEA:Ensembl.
DR   GO; GO:0072156; P:distal tubule morphogenesis; IMP:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.
DR   GO; GO:0050801; P:ion homeostasis; IMP:UniProtKB.
DR   GO; GO:0006811; P:ion transport; ISS:UniProtKB.
DR   GO; GO:0090188; P:negative regulation of pancreatic juice secretion; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0050794; P:regulation of cellular process; ISS:UniProtKB.
DR   GO; GO:0070294; P:renal sodium ion absorption; IMP:UniProtKB.
//
ID   WNT11_HUMAN             Reviewed;         354 AA.
AC   O96014; B2R8Z6; Q14DE8; Q8WZ98;
DE   RecName: Full=Protein Wnt-11;
DE   Flags: Precursor;
GN   Name=WNT11;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0030295; F:protein kinase activator activity; IMP:UniProtKB.
DR   GO; GO:0005099; F:Ras GTPase activator activity; IMP:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEP:UniProtKB.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0030282; P:bone mineralization; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0060197; P:cloacal septation; IEP:UniProtKB.
DR   GO; GO:0048706; P:embryonic skeletal system development; IEP:UniProtKB.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEP:UniProtKB.
DR   GO; GO:0072177; P:mesonephric duct development; IEP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0061037; P:negative regulation of cartilage development; NAS:UniProtKB.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0030336; P:negative regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0090272; P:negative regulation of fibroblast growth factor production; IEA:Ensembl.
DR   GO; GO:0072201; P:negative regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0061101; P:neuroendocrine cell differentiation; IMP:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0035567; P:non-canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0003151; P:outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IMP:BHF-UCL.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IMP:GOC.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0032320; P:positive regulation of Ras GTPase activity; IMP:UniProtKB.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0032915; P:positive regulation of transforming growth factor beta2 production; IEA:Ensembl.
DR   GO; GO:0034394; P:protein localization to cell surface; IMP:UniProtKB.
DR   GO; GO:0006468; P:protein phosphorylation; IMP:UniProtKB.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0070830; P:tight junction assembly; IEA:Ensembl.
DR   GO; GO:0060675; P:ureteric bud morphogenesis; IEP:UniProtKB.
DR   GO; GO:0060412; P:ventricular septum morphogenesis; IEA:Ensembl.
//
ID   WNT16_HUMAN             Reviewed;         365 AA.
AC   Q9UBV4; Q2M3G1; Q9Y5C0;
DE   RecName: Full=Protein Wnt-16;
DE   Flags: Precursor;
GN   Name=WNT16;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0030216; P:keratinocyte differentiation; IMP:BHF-UCL.
DR   GO; GO:0043616; P:keratinocyte proliferation; IMP:BHF-UCL.
DR   GO; GO:0060548; P:negative regulation of cell death; IMP:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0003408; P:optic cup formation involved in camera-type eye development; ISS:BHF-UCL.
DR   GO; GO:0090403; P:oxidative stress-induced premature senescence; IMP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:BHF-UCL.
DR   GO; GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IMP:BHF-UCL.
DR   GO; GO:0090399; P:replicative senescence; IMP:BHF-UCL.
DR   GO; GO:0016055; P:Wnt signaling pathway; IBA:RefGenome.
//
ID   WNT1_HUMAN              Reviewed;         370 AA.
AC   P04628; Q5U0N2;
DE   RecName: Full=Proto-oncogene Wnt-1;
DE   AltName: Full=Proto-oncogene Int-1 homolog;
DE   Flags: Precursor;
GN   Name=WNT1; Synonyms=INT1;
DR   GO; GO:0005125; F:cytokine activity; ISS:BHF-UCL.
DR   GO; GO:0005109; F:frizzled binding; IC:BHF-UCL.
DR   GO; GO:0048018; F:receptor agonist activity; IC:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0060348; P:bone development; IMP:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0044336; P:canonical Wnt signaling pathway involved in negative regulation of apoptotic process; IMP:BHF-UCL.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:BHF-UCL.
DR   GO; GO:0071375; P:cellular response to peptide hormone stimulus; IEA:Ensembl.
DR   GO; GO:0021551; P:central nervous system morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0021588; P:cerebellum formation; ISS:BHF-UCL.
DR   GO; GO:0021536; P:diencephalon development; IEA:Ensembl.
DR   GO; GO:0000578; P:embryonic axis specification; ISS:BHF-UCL.
DR   GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0070365; P:hepatocyte differentiation; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; ISS:BHF-UCL.
DR   GO; GO:0022004; P:midbrain-hindbrain boundary maturation during brain development; IEA:Ensembl.
DR   GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IMP:AgBase.
DR   GO; GO:0090344; P:negative regulation of cell aging; IDA:BHF-UCL.
DR   GO; GO:0022408; P:negative regulation of cell-cell adhesion; IMP:BHF-UCL.
DR   GO; GO:0010812; P:negative regulation of cell-substrate adhesion; IDA:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; ISS:BHF-UCL.
DR   GO; GO:2000059; P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0048664; P:neuron fate determination; IEA:Ensembl.
DR   GO; GO:0031100; P:organ regeneration; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0061184; P:positive regulation of dermatome development; IDA:BHF-UCL.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0010592; P:positive regulation of lamellipodium assembly; IMP:BHF-UCL.
DR   GO; GO:0045747; P:positive regulation of Notch signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0009611; P:response to wounding; IEP:UniProtKB.
DR   GO; GO:0042770; P:signal transduction in response to DNA damage; IDA:BHF-UCL.
DR   GO; GO:0060061; P:Spemann organizer formation; ISS:BHF-UCL.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
//
ID   WNT2B_HUMAN             Reviewed;         391 AA.
AC   Q93097; O14903; Q5TEI2; Q9HDC1; Q9HDC2;
DE   RecName: Full=Protein Wnt-2b;
DE   AltName: Full=Protein Wnt-13;
DE   Flags: Precursor;
GN   Name=WNT2B; Synonyms=WNT13;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0061303; P:cornea development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0021871; P:forebrain regionalization; IEP:UniProtKB.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0061072; P:iris morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0002088; P:lens development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0060492; P:lung induction; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0060638; P:mesenchymal-epithelial cell signaling; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IMP:UniProtKB.
//
ID   WNT2_HUMAN              Reviewed;         360 AA.
AC   P09544; A4D0V1; Q75N05; Q9UDP9;
DE   RecName: Full=Protein Wnt-2;
DE   AltName: Full=Int-1-like protein 1;
DE   AltName: Full=Int-1-related protein;
DE            Short=IRP;
DE   Flags: Precursor;
GN   Name=WNT2; Synonyms=INT1L1, IRP;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0048018; F:receptor agonist activity; IC:BHF-UCL.
DR   GO; GO:0055009; P:atrial cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0060317; P:cardiac epithelial to mesenchymal transition; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:BHF-UCL.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0061072; P:iris morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0060716; P:labyrinthine layer blood vessel development; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0060492; P:lung induction; IEA:Ensembl.
DR   GO; GO:0061180; P:mammary gland epithelium development; IEP:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:UniProtKB.
//
ID   WNT3A_HUMAN             Reviewed;         352 AA.
AC   P56704; Q3SY79; Q3SY80; Q969P2;
DE   RecName: Full=Protein Wnt-3a;
DE   Flags: Precursor;
GN   Name=WNT3A;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0048018; F:receptor agonist activity; IDA:BHF-UCL.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL.
DR   GO; GO:0090245; P:axis elongation involved in somitogenesis; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0061317; P:canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment; IDA:BHF-UCL.
DR   GO; GO:0021846; P:cell proliferation in forebrain; ISS:BHF-UCL.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0010387; P:COP9 signalosome assembly; ISS:BHF-UCL.
DR   GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl.
DR   GO; GO:0030879; P:mammary gland development; IEA:Ensembl.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0003136; P:negative regulation of heart induction by canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; ISS:BHF-UCL.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IMP:BHF-UCL.
DR   GO; GO:0048343; P:paraxial mesodermal cell fate commitment; IEA:Ensembl.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:2000081; P:positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation; IEA:Ensembl.
DR   GO; GO:2000727; P:positive regulation of cardiac muscle cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0035413; P:positive regulation of catenin import into nucleus; IDA:BHF-UCL.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IEA:Ensembl.
DR   GO; GO:0048697; P:positive regulation of collateral sprouting in absence of injury; IEA:Ensembl.
DR   GO; GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0061184; P:positive regulation of dermatome development; IDA:BHF-UCL.
DR   GO; GO:0048337; P:positive regulation of mesodermal cell fate specification; IDA:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0032092; P:positive regulation of protein binding; IDA:BHF-UCL.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.
DR   GO; GO:0061098; P:positive regulation of protein tyrosine kinase activity; IEA:Ensembl.
DR   GO; GO:0002092; P:positive regulation of receptor internalization; IDA:BHF-UCL.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IEA:Ensembl.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0021527; P:spinal cord association neuron differentiation; IEA:Ensembl.
DR   GO; GO:0021874; P:Wnt signaling pathway involved in forebrain neuroblast division; IEA:Ensembl.
//
ID   WNT3_HUMAN              Reviewed;         355 AA.
AC   P56703; Q2M237; Q9H1J9;
DE   RecName: Full=Proto-oncogene Wnt-3;
DE   AltName: Full=Proto-oncogene Int-4 homolog;
DE   Flags: Precursor;
GN   Name=WNT3; Synonyms=INT4;
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0048018; F:receptor agonist activity; IC:BHF-UCL.
DR   GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0044338; P:canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0044339; P:canonical Wnt signaling pathway involved in osteoblast differentiation; IMP:BHF-UCL.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0000902; P:cell morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0009950; P:dorsal/ventral axis specification; IEA:Ensembl.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0060323; P:head morphogenesis; IEA:Ensembl.
DR   GO; GO:0060174; P:limb bud formation; IMP:BHF-UCL.
DR   GO; GO:0061180; P:mammary gland epithelium development; IEP:UniProtKB.
DR   GO; GO:0001707; P:mesoderm formation; IEA:Ensembl.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0048697; P:positive regulation of collateral sprouting in absence of injury; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0060064; P:Spemann organizer formation at the anterior end of the primitive streak; IEA:Ensembl.
//
ID   WNT4_HUMAN              Reviewed;         351 AA.
AC   P56705; B4DJF9; Q5TZQ0; Q96T81; Q9BXF5; Q9H1J8; Q9UJM2;
DE   RecName: Full=Protein Wnt-4;
DE   Flags: Precursor;
GN   Name=WNT4; ORFNames=UNQ426/PRO864;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0048018; F:receptor agonist activity; IC:BHF-UCL.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IEP:UniProtKB.
DR   GO; GO:0006702; P:androgen biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0001838; P:embryonic epithelial tube formation; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEP:UniProtKB.
DR   GO; GO:0090002; P:establishment of protein localization to plasma membrane; IDA:UniProtKB.
DR   GO; GO:0008585; P:female gonad development; ISS:UniProtKB.
DR   GO; GO:0030237; P:female sex determination; IMP:UniProtKB.
DR   GO; GO:0033080; P:immature T cell proliferation in thymus; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEP:UniProtKB.
DR   GO; GO:0001889; P:liver development; IEP:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IMP:UniProtKB.
DR   GO; GO:0061180; P:mammary gland epithelium development; IEP:UniProtKB.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; IEA:Ensembl.
DR   GO; GO:0072164; P:mesonephric tubule development; IEA:Ensembl.
DR   GO; GO:0072162; P:metanephric mesenchymal cell differentiation; NAS:UniProtKB.
DR   GO; GO:0072273; P:metanephric nephron morphogenesis; IEA:Ensembl.
DR   GO; GO:2001234; P:negative regulation of apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0030336; P:negative regulation of cell migration; IEA:Ensembl.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:2000019; P:negative regulation of male gonad development; IMP:UniProtKB.
DR   GO; GO:0010894; P:negative regulation of steroid biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0061369; P:negative regulation of testicular blood vessel morphogenesis; IMP:UniProtKB.
DR   GO; GO:2000225; P:negative regulation of testosterone biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0061045; P:negative regulation of wound healing; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0038030; P:non-canonical Wnt signaling pathway via MAPK cascade; IDA:BHF-UCL.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0061205; P:paramesonephric duct development; IMP:UniProtKB.
DR   GO; GO:0032349; P:positive regulation of aldosterone biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0030501; P:positive regulation of bone mineralization; IDA:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:2000066; P:positive regulation of cortisol biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0061184; P:positive regulation of dermatome development; IDA:BHF-UCL.
DR   GO; GO:0051894; P:positive regulation of focal adhesion assembly; IEA:Ensembl.
DR   GO; GO:0045836; P:positive regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IDA:BHF-UCL.
DR   GO; GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Ensembl.
DR   GO; GO:0051496; P:positive regulation of stress fiber assembly; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProtKB.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IEA:Ensembl.
DR   GO; GO:0072033; P:renal vesicle formation; IEA:Ensembl.
DR   GO; GO:0072034; P:renal vesicle induction; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0060126; P:somatotropin secreting cell differentiation; IEA:Ensembl.
DR   GO; GO:0060748; P:tertiary branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0060129; P:thyroid-stimulating hormone-secreting cell differentiation; IEA:Ensembl.
//
ID   WNT5A_HUMAN             Reviewed;         380 AA.
AC   P41221; A8K4A4; Q6P278;
DE   RecName: Full=Protein Wnt-5a;
DE   Flags: Precursor;
GN   Name=WNT5A;
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0048018; F:receptor agonist activity; IC:BHF-UCL.
DR   GO; GO:0005115; F:receptor tyrosine kinase-like orphan receptor binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0000187; P:activation of MAPK activity; IDA:BHF-UCL.
DR   GO; GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.
DR   GO; GO:0001667; P:ameboidal cell migration; IEA:Ensembl.
DR   GO; GO:0008595; P:anterior/posterior axis specification, embryo; IEA:Ensembl.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0034613; P:cellular protein localization; IDA:UniProtKB.
DR   GO; GO:0071277; P:cellular response to calcium ion; IEP:UniProtKB.
DR   GO; GO:0071346; P:cellular response to interferon-gamma; IEP:UniProtKB.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IEP:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0060067; P:cervix development; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0060029; P:convergent extension involved in organogenesis; IEA:Ensembl.
DR   GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0048706; P:embryonic skeletal system development; IMP:BHF-UCL.
DR   GO; GO:0060750; P:epithelial cell proliferation involved in mammary gland duct elongation; IEA:Ensembl.
DR   GO; GO:0001837; P:epithelial to mesenchymal transition; IEP:UniProtKB.
DR   GO; GO:0001736; P:establishment of planar polarity; IEA:Ensembl.
DR   GO; GO:0060324; P:face development; IMP:BHF-UCL.
DR   GO; GO:0048806; P:genitalia development; IMP:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0071425; P:hematopoietic stem cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0007442; P:hindgut morphogenesis; IEA:Ensembl.
DR   GO; GO:0048850; P:hypophysis morphogenesis; IEA:Ensembl.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEP:BHF-UCL.
DR   GO; GO:0060599; P:lateral sprouting involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0002088; P:lens development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0060744; P:mammary gland branching involved in thelarche; IEA:Ensembl.
DR   GO; GO:0060638; P:mesenchymal-epithelial cell signaling; IEA:Ensembl.
DR   GO; GO:0007494; P:midgut development; IEA:Ensembl.
DR   GO; GO:0050919; P:negative chemotaxis; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0048843; P:negative regulation of axon extension involved in axon guidance; IEA:Ensembl.
DR   GO; GO:0030514; P:negative regulation of BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IMP:BHF-UCL.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0072201; P:negative regulation of mesenchymal cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060686; P:negative regulation of prostatic bud formation; IEA:Ensembl.
DR   GO; GO:0051964; P:negative regulation of synapse assembly; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0038031; P:non-canonical Wnt signaling pathway via JNK cascade; IEA:Ensembl.
DR   GO; GO:0021891; P:olfactory bulb interneuron development; ISS:UniProtKB.
DR   GO; GO:0003408; P:optic cup formation involved in camera-type eye development; ISS:BHF-UCL.
DR   GO; GO:0060021; P:palate development; IMP:BHF-UCL.
DR   GO; GO:0061350; P:planar cell polarity pathway involved in cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0061349; P:planar cell polarity pathway involved in cardiac right atrium morphogenesis; IEA:Ensembl.
DR   GO; GO:0090179; P:planar cell polarity pathway involved in neural tube closure; IEA:Ensembl.
DR   GO; GO:0061347; P:planar cell polarity pathway involved in outflow tract morphogenesis; IEA:Ensembl.
DR   GO; GO:0061354; P:planar cell polarity pathway involved in pericardium morphogenesis; IEA:Ensembl.
DR   GO; GO:0061348; P:planar cell polarity pathway involved in ventricular septum morphogenesis; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:2000049; P:positive regulation of cell-cell adhesion mediated by cadherin; IEA:Ensembl.
DR   GO; GO:0030825; P:positive regulation of cGMP metabolic process; IDA:BHF-UCL.
DR   GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IMP:UniProtKB.
DR   GO; GO:0002741; P:positive regulation of cytokine secretion involved in immune response; IMP:UniProtKB.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IMP:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IDA:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IMP:BHF-UCL.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
DR   GO; GO:0050718; P:positive regulation of interleukin-1 beta secretion; IMP:BHF-UCL.
DR   GO; GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.
DR   GO; GO:2000484; P:positive regulation of interleukin-8 secretion; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IEA:Ensembl.
DR   GO; GO:0043032; P:positive regulation of macrophage activation; IMP:BHF-UCL.
DR   GO; GO:0060907; P:positive regulation of macrophage cytokine production; IMP:UniProtKB.
DR   GO; GO:0045836; P:positive regulation of meiosis; IEA:Ensembl.
DR   GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045778; P:positive regulation of ossification; IMP:BHF-UCL.
DR   GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
DR   GO; GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IEA:Ensembl.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IGI:MGI.
DR   GO; GO:0090037; P:positive regulation of protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0060760; P:positive regulation of response to cytokine stimulus; IDA:UniProtKB.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IMP:UniProtKB.
DR   GO; GO:0070245; P:positive regulation of thymocyte apoptotic process; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl.
DR   GO; GO:0090009; P:primitive streak formation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEP:UniProtKB.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0003323; P:type B pancreatic cell development; IEA:Ensembl.
DR   GO; GO:0060157; P:urinary bladder development; IEA:Ensembl.
DR   GO; GO:0060065; P:uterus development; IEA:Ensembl.
DR   GO; GO:0060068; P:vagina development; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0007223; P:Wnt signaling pathway, calcium modulating pathway; IMP:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IDA:UniProtKB.
//
ID   WNT5B_HUMAN             Reviewed;         359 AA.
AC   Q9H1J7; A8K315; D3DUP9; Q96S49; Q9BV04;
DE   RecName: Full=Protein Wnt-5b;
DE   Flags: Precursor;
GN   Name=WNT5B;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0005102; F:receptor binding; IPI:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0002062; P:chondrocyte differentiation; IEP:UniProtKB.
DR   GO; GO:0045444; P:fat cell differentiation; NAS:UniProtKB.
DR   GO; GO:0070307; P:lens fiber cell development; ISS:BHF-UCL.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0042060; P:wound healing; IEA:Ensembl.
//
ID   WNT6_HUMAN              Reviewed;         365 AA.
AC   Q9Y6F9; Q9H1J6; Q9H238;
DE   RecName: Full=Protein Wnt-6;
DE   Flags: Precursor;
GN   Name=WNT6;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0009798; P:axis specification; IEA:Ensembl.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0061303; P:cornea development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0060684; P:epithelial-mesenchymal cell signaling; IEA:Ensembl.
DR   GO; GO:0072079; P:nephron tubule formation; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL.
DR   GO; GO:0070172; P:positive regulation of tooth mineralization; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IBA:RefGenome.
//
ID   WNT7A_HUMAN             Reviewed;         349 AA.
AC   O00755; Q96H90; Q9Y560;
DE   RecName: Full=Protein Wnt-7a;
DE   Flags: Precursor;
GN   Name=WNT7A;
DR   GO; GO:0005125; F:cytokine activity; IDA:BHF-UCL.
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0048018; F:receptor agonist activity; IDA:BHF-UCL.
DR   GO; GO:0005102; F:receptor binding; IPI:BHF-UCL.
DR   GO; GO:0008105; P:asymmetric protein localization; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0001502; P:cartilage condensation; IDA:AgBase.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IDA:BHF-UCL.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.
DR   GO; GO:0022009; P:central nervous system vasculogenesis; IEA:Ensembl.
DR   GO; GO:0021707; P:cerebellar granule cell differentiation; IEA:Ensembl.
DR   GO; GO:0002062; P:chondrocyte differentiation; IDA:AgBase.
DR   GO; GO:0009953; P:dorsal/ventral pattern formation; IEA:Ensembl.
DR   GO; GO:0000578; P:embryonic axis specification; IMP:BHF-UCL.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IMP:BHF-UCL.
DR   GO; GO:0030010; P:establishment of cell polarity; IEA:Ensembl.
DR   GO; GO:0070307; P:lens fiber cell development; ISS:BHF-UCL.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IDA:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0007269; P:neurotransmitter secretion; IEA:Ensembl.
DR   GO; GO:0035567; P:non-canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060066; P:oviduct development; IEA:Ensembl.
DR   GO; GO:0060021; P:palate development; IMP:BHF-UCL.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0060054; P:positive regulation of epithelial cell proliferation involved in wound healing; IDA:BHF-UCL.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:0051965; P:positive regulation of synapse assembly; IDA:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0031133; P:regulation of axon diameter; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; IEA:Ensembl.
DR   GO; GO:0014719; P:satellite cell activation; IEA:Ensembl.
DR   GO; GO:0014834; P:satellite cell maintenance involved in skeletal muscle regeneration; IEA:Ensembl.
DR   GO; GO:0007548; P:sex differentiation; TAS:ProtInc.
DR   GO; GO:0048103; P:somatic stem cell division; IEA:Ensembl.
DR   GO; GO:0048864; P:stem cell development; IDA:BHF-UCL.
DR   GO; GO:0050808; P:synapse organization; IEA:Ensembl.
DR   GO; GO:0061038; P:uterus morphogenesis; IEA:Ensembl.
DR   GO; GO:0035659; P:Wnt signaling pathway involved in wound healing, spreading of epidermal cells; IDA:BHF-UCL.
//
ID   WNT7B_HUMAN             Reviewed;         349 AA.
AC   P56706; B8A596; Q96Q12;
DE   RecName: Full=Protein Wnt-7b;
DE   Flags: Precursor;
GN   Name=WNT7B;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0007257; P:activation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0060033; P:anatomical structure regression; IEA:Ensembl.
DR   GO; GO:1902262; P:apoptotic process involved in patterning of blood vessels; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0044237; P:cellular metabolic process; ISS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; IEP:UniProtKB.
DR   GO; GO:0022009; P:central nervous system vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0060710; P:chorio-allantoic fusion; ISS:UniProtKB.
DR   GO; GO:0060560; P:developmental growth involved in morphogenesis; ISS:UniProtKB.
DR   GO; GO:0048568; P:embryonic organ development; ISS:UniProtKB.
DR   GO; GO:0060669; P:embryonic placenta morphogenesis; ISS:UniProtKB.
DR   GO; GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; ISS:UniProtKB.
DR   GO; GO:0048144; P:fibroblast proliferation; IEP:UniProtKB.
DR   GO; GO:0021871; P:forebrain regionalization; IEP:UniProtKB.
DR   GO; GO:0042592; P:homeostatic process; ISS:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
DR   GO; GO:0072061; P:inner medullary collecting duct development; ISS:UniProtKB.
DR   GO; GO:0070307; P:lens fiber cell development; ISS:BHF-UCL.
DR   GO; GO:0060482; P:lobar bronchus development; ISS:UniProtKB.
DR   GO; GO:0030324; P:lung development; ISS:UniProtKB.
DR   GO; GO:0060428; P:lung epithelium development; ISS:UniProtKB.
DR   GO; GO:0060425; P:lung morphogenesis; ISS:UniProtKB.
DR   GO; GO:0060484; P:lung-associated mesenchyme development; IEA:Ensembl.
DR   GO; GO:0061180; P:mammary gland epithelium development; IEP:UniProtKB.
DR   GO; GO:0072205; P:metanephric collecting duct development; ISS:UniProtKB.
DR   GO; GO:0072207; P:metanephric epithelium development; ISS:UniProtKB.
DR   GO; GO:0072236; P:metanephric loop of Henle development; ISS:UniProtKB.
DR   GO; GO:0003338; P:metanephros morphogenesis; ISS:UniProtKB.
DR   GO; GO:0045879; P:negative regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; IEP:UniProtKB.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
DR   GO; GO:0072060; P:outer medullary collecting duct development; ISS:UniProtKB.
DR   GO; GO:0032364; P:oxygen homeostasis; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.
DR   GO; GO:0032536; P:regulation of cell projection size; IEA:Ensembl.
DR   GO; GO:0072053; P:renal inner medulla development; ISS:UniProtKB.
DR   GO; GO:0072054; P:renal outer medulla development; ISS:UniProtKB.
DR   GO; GO:0051384; P:response to glucocorticoid; IEA:Ensembl.
DR   GO; GO:0051145; P:smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0072089; P:stem cell proliferation; IEP:UniProtKB.
DR   GO; GO:0050808; P:synapse organization; ISS:UniProtKB.
DR   GO; GO:0060535; P:trachea cartilage morphogenesis; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; ISS:UniProtKB.
//
ID   WNT8A_HUMAN             Reviewed;         351 AA.
AC   Q9H1J5; Q96S51;
DE   RecName: Full=Protein Wnt-8a;
DE   AltName: Full=Protein Wnt-8d;
DE   Flags: Precursor;
GN   Name=WNT8A; Synonyms=WNT8D;
DR   GO; GO:0005109; F:frizzled binding; NAS:BHF-UCL.
DR   GO; GO:0048018; F:receptor agonist activity; NAS:BHF-UCL.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; ISS:BHF-UCL.
DR   GO; GO:0061317; P:canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment; IEP:BHF-UCL.
DR   GO; GO:0044335; P:canonical Wnt signaling pathway involved in neural crest cell differentiation; ISS:BHF-UCL.
DR   GO; GO:0007492; P:endoderm development; IEA:Ensembl.
DR   GO; GO:0048561; P:establishment of organ orientation; IEA:Ensembl.
DR   GO; GO:0014034; P:neural crest cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0030182; P:neuron differentiation; IBA:RefGenome.
DR   GO; GO:0060021; P:palate development; IMP:BHF-UCL.
DR   GO; GO:0009949; P:polarity specification of anterior/posterior axis; IEA:Ensembl.
DR   GO; GO:0010085; P:polarity specification of proximal/distal axis; IEA:Ensembl.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:Ensembl.
DR   GO; GO:0044324; P:regulation of transcription involved in anterior/posterior axis specification; ISS:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; NAS:BHF-UCL.
//
ID   WNT8B_HUMAN             Reviewed;         351 AA.
AC   Q93098; O00771; Q5VX55; Q8WYK9;
DE   RecName: Full=Protein Wnt-8b;
DE   Flags: Precursor;
GN   Name=WNT8B;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0048263; P:determination of dorsal identity; ISS:BHF-UCL.
DR   GO; GO:0007369; P:gastrulation; ISS:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; TAS:ProtInc.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0032355; P:response to estradiol; NAS:BHF-UCL.
DR   GO; GO:0032526; P:response to retinoic acid; NAS:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016055; P:Wnt signaling pathway; IBA:RefGenome.
//
ID   WNT9A_HUMAN             Reviewed;         365 AA.
AC   O14904; A6NLW2; Q2M2J3; Q5VWU0; Q96S50;
DE   RecName: Full=Protein Wnt-9a;
DE   AltName: Full=Protein Wnt-14;
DE   Flags: Precursor;
GN   Name=WNT9A; Synonyms=WNT14;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0061303; P:cornea development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0072498; P:embryonic skeletal joint development; ISS:BHF-UCL.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0061072; P:iris morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:BHF-UCL.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0061037; P:negative regulation of cartilage development; IEA:Ensembl.
DR   GO; GO:0060548; P:negative regulation of cell death; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.
DR   GO; GO:0032331; P:negative regulation of chondrocyte differentiation; ISS:BHF-UCL.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Ensembl.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0045880; P:positive regulation of smoothened signaling pathway; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IBA:RefGenome.
//
ID   WNT9B_HUMAN             Reviewed;         357 AA.
AC   O14905; Q6UXT4; Q96Q09;
DE   RecName: Full=Protein Wnt-9b;
DE   AltName: Full=Protein Wnt-14b;
DE   AltName: Full=Protein Wnt-15;
DE   Flags: Precursor;
GN   Name=WNT9B; Synonyms=WNT14B, WNT15; ORFNames=UNQ6973/PRO21956;
DR   GO; GO:0005109; F:frizzled binding; IBA:RefGenome.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
DR   GO; GO:0045165; P:cell fate commitment; IBA:RefGenome.
DR   GO; GO:0007267; P:cell-cell signaling; NAS:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0072044; P:collecting duct development; IEA:Ensembl.
DR   GO; GO:0061303; P:cornea development in camera-type eye; ISS:BHF-UCL.
DR   GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
DR   GO; GO:0072046; P:establishment of planar polarity involved in nephron morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0072003; P:kidney rudiment formation; IEA:Ensembl.
DR   GO; GO:0030539; P:male genitalia development; IEA:Ensembl.
DR   GO; GO:0072181; P:mesonephric duct formation; IEA:Ensembl.
DR   GO; GO:0072170; P:metanephric tubule development; IEA:Ensembl.
DR   GO; GO:0007275; P:multicellular organismal development; NAS:UniProtKB.
DR   GO; GO:0030182; P:neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0060021; P:palate development; IEA:Ensembl.
DR   GO; GO:0043085; P:positive regulation of catalytic activity; IEA:Ensembl.
DR   GO; GO:0009786; P:regulation of asymmetric cell division; IEA:Ensembl.
DR   GO; GO:0003339; P:regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0001932; P:regulation of protein phosphorylation; IEA:Ensembl.
DR   GO; GO:0035150; P:regulation of tube size; IEA:Ensembl.
DR   GO; GO:0032526; P:response to retinoic acid; NAS:BHF-UCL.
DR   GO; GO:0061038; P:uterus morphogenesis; IEA:Ensembl.
DR   GO; GO:0016055; P:Wnt signaling pathway; IBA:RefGenome.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   WRB_HUMAN               Reviewed;         174 AA.
AC   O00258; A8KAP8; A8MQ44; D3DSH9; O60740;
DE   RecName: Full=Tail-anchored protein insertion receptor WRB;
DE   AltName: Full=Congenital heart disease 5 protein;
DE   AltName: Full=Tryptophan-rich basic protein;
DE            Short=WRB;
GN   Name=WRB; Synonyms=CHD5;
//
ID   WRIP1_HUMAN             Reviewed;         665 AA.
AC   Q96S55; B2RDB0; Q53EP6; Q59ET8; Q5W0E2; Q5W0E4; Q8WV26; Q9H681;
AC   Q9NRJ6;
DE   RecName: Full=ATPase WRNIP1;
DE            EC=3.6.1.3;
DE   AltName: Full=Werner helicase-interacting protein 1;
GN   Name=WRNIP1; Synonyms=WHIP;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IMP:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IMP:GOC.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0030174; P:regulation of DNA-dependent DNA replication initiation; IDA:UniProtKB.
//
ID   WRN_HUMAN               Reviewed;        1432 AA.
AC   Q14191; A1KYY9;
DE   RecName: Full=Werner syndrome ATP-dependent helicase;
DE            EC=3.6.4.12;
DE   AltName: Full=DNA helicase, RecQ-like type 3;
DE            Short=RecQ3;
DE   AltName: Full=Exonuclease WRN;
DE            EC=3.1.-.-;
DE   AltName: Full=RecQ protein-like 2;
GN   Name=WRN; Synonyms=RECQ3, RECQL2;
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IDA:UniProtKB.
DR   GO; GO:0016887; F:ATPase activity; IDA:UniProtKB.
DR   GO; GO:0000405; F:bubble DNA binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003678; F:DNA helicase activity; IMP:UniProtKB.
DR   GO; GO:0004527; F:exonuclease activity; IDA:MGI.
DR   GO; GO:0009378; F:four-way junction helicase activity; IDA:UniProtKB.
DR   GO; GO:0051880; F:G-quadruplex DNA binding; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IDA:UniProtKB.
DR   GO; GO:0000287; F:magnesium ion binding; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0032403; F:protein complex binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0000403; F:Y-form DNA binding; IDA:UniProtKB.
DR   GO; GO:0007568; P:aging; NAS:UniProtKB.
DR   GO; GO:0006200; P:ATP catabolic process; IDA:GOC.
DR   GO; GO:0006284; P:base-excision repair; IDA:UniProtKB.
DR   GO; GO:0007569; P:cell aging; IMP:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0009267; P:cellular response to starvation; IDA:MGI.
DR   GO; GO:0032508; P:DNA duplex unwinding; IDA:GOC.
DR   GO; GO:0006259; P:DNA metabolic process; IDA:UniProtKB.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IMP:UniProtKB.
DR   GO; GO:0000731; P:DNA synthesis involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0006302; P:double-strand break repair; IMP:UniProtKB.
DR   GO; GO:0010259; P:multicellular organismal aging; IMP:UniProtKB.
DR   GO; GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IDA:GOC.
DR   GO; GO:0032066; P:nucleolus to nucleoplasm transport; IDA:MGI.
DR   GO; GO:0051345; P:positive regulation of hydrolase activity; IDA:UniProtKB.
DR   GO; GO:0042981; P:regulation of apoptotic process; IGI:MGI.
DR   GO; GO:0040009; P:regulation of growth rate; IEA:Ensembl.
DR   GO; GO:0031297; P:replication fork processing; IDA:UniProtKB.
DR   GO; GO:0001302; P:replicative cell aging; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0010225; P:response to UV-C; IDA:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:UniProtKB.
//
ID   WRP73_HUMAN             Reviewed;         460 AA.
AC   Q9P2S5; Q5T0D6; Q9BUH7; Q9NTK7; Q9NX56;
DE   RecName: Full=WD repeat-containing protein WRAP73;
DE   AltName: Full=WD repeat-containing protein 8;
DE   AltName: Full=WD repeat-containing protein antisense to TP73 gene;
GN   Name=WRAP73; Synonyms=WDR8;
//
ID   WSB1_HUMAN              Reviewed;         421 AA.
AC   Q9Y6I7; Q9NRB1; Q9UBH9; Q9UG25; Q9UNN6; Q9Y656;
DE   RecName: Full=WD repeat and SOCS box-containing protein 1;
DE            Short=WSB-1;
DE   AltName: Full=SOCS box-containing WD protein SWiP-1;
GN   Name=WSB1; Synonyms=SWIP1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   WSB2_HUMAN              Reviewed;         404 AA.
AC   Q9NYS7; B4DIE6; B4DPV6; Q9NRX9;
DE   RecName: Full=WD repeat and SOCS box-containing protein 2;
DE            Short=WSB-2;
DE   AltName: Full=CS box-containing WD protein;
GN   Name=WSB2;
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   WSCD1_HUMAN             Reviewed;         575 AA.
AC   Q658N2; A8K0N8; D3DTM3; O60276; Q96G45;
DE   RecName: Full=WSC domain-containing protein 1;
GN   Name=WSCD1; Synonyms=KIAA0523;
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
//
ID   WSCD2_HUMAN             Reviewed;         565 AA.
AC   Q2TBF2; B2RN48; Q8IY35; Q9Y4B7;
DE   RecName: Full=WSC domain-containing protein 2;
GN   Name=WSCD2; Synonyms=KIAA0789;
//
ID   WSDU1_HUMAN             Reviewed;         476 AA.
AC   Q8N9V3; Q53TI9; Q8N6N8;
DE   RecName: Full=WD repeat, SAM and U-box domain-containing protein 1;
GN   Name=WDSUB1; Synonyms=WDSAM1;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
//
ID   WT1_HUMAN               Reviewed;         449 AA.
AC   P19544; A8K6S1; B3KSA5; Q15881; Q16256; Q16575; Q4VXV4; Q4VXV5;
AC   Q4VXV6; Q8IYZ5;
DE   RecName: Full=Wilms tumor protein;
DE   AltName: Full=WT33;
GN   Name=WT1;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.
DR   GO; GO:0030325; P:adrenal gland development; IGI:UniProtKB.
DR   GO; GO:0006309; P:apoptotic DNA fragmentation; IDA:UniProtKB.
DR   GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:UniProtKB.
DR   GO; GO:0043010; P:camera-type eye development; ISS:UniProtKB.
DR   GO; GO:0060923; P:cardiac muscle cell fate commitment; ISS:BHF-UCL.
DR   GO; GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.
DR   GO; GO:0071371; P:cellular response to gonadotropin stimulus; IDA:UniProtKB.
DR   GO; GO:0060539; P:diaphragm development; ISS:UniProtKB.
DR   GO; GO:0030855; P:epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0007281; P:germ cell development; ISS:UniProtKB.
DR   GO; GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.
DR   GO; GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032835; P:glomerulus development; IGI:UniProtKB.
DR   GO; GO:0008406; P:gonad development; ISS:UniProtKB.
DR   GO; GO:0007507; P:heart development; IGI:UniProtKB.
DR   GO; GO:0001822; P:kidney development; IGI:UniProtKB.
DR   GO; GO:0030539; P:male genitalia development; ISS:UniProtKB.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.
DR   GO; GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.
DR   GO; GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.
DR   GO; GO:0072284; P:metanephric S-shaped body morphogenesis; IGI:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IGI:UniProtKB.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.
DR   GO; GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IDA:UniProtKB.
DR   GO; GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.
DR   GO; GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.
DR   GO; GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:GOC.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.
DR   GO; GO:0003156; P:regulation of organ formation; ISS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; ISS:UniProtKB.
DR   GO; GO:0007530; P:sex determination; IDA:UniProtKB.
DR   GO; GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.
DR   GO; GO:0009888; P:tissue development; ISS:UniProtKB.
DR   GO; GO:0001657; P:ureteric bud development; ISS:UniProtKB.
DR   GO; GO:0001570; P:vasculogenesis; ISS:UniProtKB.
DR   GO; GO:0061032; P:visceral serous pericardium development; IGI:UniProtKB.
//
ID   WTIP_HUMAN              Reviewed;         430 AA.
AC   A6NIX2;
DE   RecName: Full=Wilms tumor protein 1-interacting protein;
DE            Short=WT1-interacting protein;
GN   Name=WTIP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0035195; P:gene silencing by miRNA; IMP:MGI.
DR   GO; GO:0035331; P:negative regulation of hippo signaling; IDA:UniProtKB.
DR   GO; GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001666; P:response to hypoxia; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   WWAS2_HUMAN             Reviewed;         200 AA.
AC   Q96NR7;
DE   RecName: Full=Putative uncharacterized protein WWC2-AS2;
DE   AltName: Full=WWC2 antisense RNA 2;
DE   AltName: Full=WWC2 antisense gene protein 2;
GN   Name=WWC2-AS2; Synonyms=C4orf38;
//
ID   WWC2_HUMAN              Reviewed;        1192 AA.
AC   Q6AWC2; Q32Q84; Q69YQ1; Q6AWB8; Q6ZSY9; Q6ZU09; Q7Z620; Q8TEB8;
AC   Q9H6P0;
DE   RecName: Full=Protein WWC2;
DE   AltName: Full=BH-3-only member B;
DE   AltName: Full=WW domain-containing protein 2;
GN   Name=WWC2; Synonyms=BOMB;
//
ID   WWC3_HUMAN              Reviewed;        1092 AA.
AC   Q9ULE0; A8KA96; Q659C1; Q9BTQ1;
DE   RecName: Full=Protein WWC3;
GN   Name=WWC3; Synonyms=KIAA1280;
//
ID   WWOX_HUMAN              Reviewed;         414 AA.
AC   Q9NZC7; A8K323; Q5MYT5; Q96KM3; Q96RF2; Q9BTT8; Q9NPC9; Q9NRF4;
AC   Q9NRF5; Q9NRF6; Q9NRK1; Q9NZC5;
DE   RecName: Full=WW domain-containing oxidoreductase;
DE            EC=1.1.1.-;
DE   AltName: Full=Fragile site FRA16D oxidoreductase;
GN   Name=WWOX; Synonyms=FOR, WOX1;
DR   GO; GO:0050662; F:coenzyme binding; TAS:UniProtKB.
DR   GO; GO:0048037; F:cofactor binding; TAS:UniProtKB.
DR   GO; GO:0019899; F:enzyme binding; IPI:BHF-UCL.
DR   GO; GO:0016491; F:oxidoreductase activity; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; TAS:UniProtKB.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:BHF-UCL.
DR   GO; GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR   GO; GO:0030178; P:negative regulation of Wnt signaling pathway; IDA:UniProtKB.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0055114; P:oxidation-reduction process; TAS:UniProtKB.
DR   GO; GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; ISS:BHF-UCL.
DR   GO; GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.
DR   GO; GO:0048705; P:skeletal system morphogenesis; ISS:BHF-UCL.
DR   GO; GO:0008202; P:steroid metabolic process; TAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   WWP1_HUMAN              Reviewed;         922 AA.
AC   Q9H0M0; O00307; Q5YLC1; Q96BP4;
DE   RecName: Full=NEDD4-like E3 ubiquitin-protein ligase WWP1;
DE            EC=6.3.2.-;
DE   AltName: Full=Atrophin-1-interacting protein 5;
DE            Short=AIP5;
DE   AltName: Full=TGIF-interacting ubiquitin ligase 1;
DE            Short=Tiul1;
DE   AltName: Full=WW domain-containing protein 1;
GN   Name=WWP1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; NAS:UniProtKB.
DR   GO; GO:0034220; P:ion transmembrane transport; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; TAS:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
//
ID   WWP2_HUMAN              Reviewed;         870 AA.
AC   O00308; A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; I3RSG8; Q6ZTQ5;
AC   Q96CZ2; Q9BWN6;
DE   RecName: Full=NEDD4-like E3 ubiquitin-protein ligase WWP2;
DE            EC=6.3.2.-;
DE   AltName: Full=Atrophin-1-interacting protein 2;
DE            Short=AIP2;
DE   AltName: Full=WW domain-containing protein 2;
GN   Name=WWP2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.
DR   GO; GO:0008134; F:transcription factor binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0010629; P:negative regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0051224; P:negative regulation of protein transport; IMP:UniProtKB.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:BHF-UCL.
DR   GO; GO:0032410; P:negative regulation of transporter activity; IDA:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:FlyBase.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IDA:BHF-UCL.
DR   GO; GO:0042391; P:regulation of membrane potential; IDA:BHF-UCL.
DR   GO; GO:1901016; P:regulation of potassium ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0046718; P:viral entry into host cell; TAS:UniProtKB.
//
ID   WWTR1_HUMAN             Reviewed;         400 AA.
AC   Q9GZV5; D3DNH7; Q8N3P2; Q9Y3W6;
DE   RecName: Full=WW domain-containing transcription regulator protein 1;
DE   AltName: Full=Transcriptional coactivator with PDZ-binding motif;
GN   Name=WWTR1; Synonyms=TAZ;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0032835; P:glomerulus development; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; IDA:UniProtKB.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.
DR   GO; GO:0045599; P:negative regulation of fat cell differentiation; IEA:Ensembl.
DR   GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IMP:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0060390; P:regulation of SMAD protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0017145; P:stem cell division; IDA:UniProtKB.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
//
ID   X3CL1_HUMAN             Reviewed;         397 AA.
AC   P78423; O00672;
DE   RecName: Full=Fractalkine;
DE   AltName: Full=C-X3-C motif chemokine 1;
DE   AltName: Full=CX3C membrane-anchored chemokine;
DE   AltName: Full=Neurotactin;
DE   AltName: Full=Small-inducible cytokine D1;
DE   Contains:
DE     RecName: Full=Processed fractalkine;
DE   Flags: Precursor;
GN   Name=CX3CL1; Synonyms=FKN, NTT, SCYD1; ORFNames=A-152E5.2;
DR   GO; GO:0008009; F:chemokine activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0005102; F:receptor binding; TAS:UniProtKB.
DR   GO; GO:0060055; P:angiogenesis involved in wound healing; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:UniProtKB.
DR   GO; GO:0006952; P:defense response; TAS:UniProtKB.
DR   GO; GO:0006955; P:immune response; TAS:UniProtKB.
DR   GO; GO:0050902; P:leukocyte adhesive activation; TAS:UniProtKB.
DR   GO; GO:0030595; P:leukocyte chemotaxis; TAS:UniProtKB.
DR   GO; GO:0048247; P:lymphocyte chemotaxis; IEA:Ensembl.
DR   GO; GO:0048246; P:macrophage chemotaxis; IEA:Ensembl.
DR   GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR   GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
DR   GO; GO:0045766; P:positive regulation of angiogenesis; IEA:Ensembl.
DR   GO; GO:0051041; P:positive regulation of calcium-independent cell-cell adhesion; IDA:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; IEP:UniProtKB.
DR   GO; GO:0032914; P:positive regulation of transforming growth factor beta1 production; IEA:Ensembl.
//
ID   XAF1_HUMAN              Reviewed;         301 AA.
AC   Q6GPH4; A2T931; A2T932; A8K2L1; A8K9Y3; D3DTM6; Q6MZE8; Q8N557;
AC   Q99982;
DE   RecName: Full=XIAP-associated factor 1;
DE   AltName: Full=BIRC4-binding protein;
GN   Name=XAF1; Synonyms=BIRC4BP, XIAPAF1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
DR   GO; GO:0031333; P:negative regulation of protein complex assembly; IEA:Ensembl.
DR   GO; GO:0035456; P:response to interferon-beta; IDA:BHF-UCL.
DR   GO; GO:0060337; P:type I interferon signaling pathway; TAS:Reactome.
//
ID   XAGE1_HUMAN             Reviewed;          81 AA.
AC   Q9HD64; A6NJ94; Q5JPN8; Q5JPP0; Q5JPP3; Q8WWG5; Q8WWG6; Q969J6;
DE   RecName: Full=X antigen family member 1;
DE            Short=XAGE-1;
DE   AltName: Full=Cancer/testis antigen 12.1;
DE            Short=CT12.1;
DE   AltName: Full=G antigen family D member 2;
GN   Name=XAGE1A; Synonyms=GAGED2, XAGE1;
GN   and
GN   Name=XAGE1B;
GN   and
GN   Name=XAGE1C;
GN   and
GN   Name=XAGE1D;
GN   and
GN   Name=XAGE1E;
//
ID   XAGE2_HUMAN             Reviewed;         111 AA.
AC   Q96GT9; Q5HYR4;
DE   RecName: Full=X antigen family member 2;
DE            Short=XAGE-2;
DE   AltName: Full=Cancer/testis antigen 12.2;
DE            Short=CT12.2;
DE   AltName: Full=G antigen family D member 3;
GN   Name=XAGE2; Synonyms=GAGED3;
GN   and
GN   Name=XAGE2B;
//
ID   XAGE3_HUMAN             Reviewed;         111 AA.
AC   Q8WTP9; Q5JS82; Q8WYS9;
DE   RecName: Full=X antigen family member 3;
DE            Short=XAGE-3;
DE   AltName: Full=Cancer/testis antigen 12.3;
DE            Short=CT12.3;
DE   AltName: Full=G antigen family D member 4;
DE   AltName: Full=Placenta-specific gene 6 protein;
GN   Name=XAGE3; Synonyms=GAGED4, PLAC6; ORFNames=PP9012;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   XAGE5_HUMAN             Reviewed;         108 AA.
AC   Q8WWM1; Q5JS81;
DE   RecName: Full=X antigen family member 5;
DE            Short=XAGE-5;
DE   AltName: Full=Cancer/testis antigen 12.5;
DE            Short=CT12.5;
DE   AltName: Full=G antigen family D member 5;
GN   Name=XAGE5; Synonyms=GAGED5;
//
ID   XBP1_HUMAN              Reviewed;         261 AA.
AC   P17861; Q8WYK6; Q969P1; Q96BD7;
DE   RecName: Full=X-box-binding protein 1;
DE            Short=XBP-1;
DE   AltName: Full=Tax-responsive element-binding protein 5;
GN   Name=XBP1; Synonyms=TREB5, XBP2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0071236; P:cellular response to antibiotic; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0060691; P:epithelial cell maturation involved in salivary gland development; IEA:Ensembl.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:1900103; P:positive regulation of endoplasmic reticulum unfolded protein response; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0051602; P:response to electrical stimulus; IEA:Ensembl.
DR   GO; GO:0060096; P:serotonin secretion, neurotransmission; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:Ensembl.
//
ID   XCL1_HUMAN              Reviewed;         114 AA.
AC   P47992; Q52MA8;
DE   RecName: Full=Lymphotactin;
DE   AltName: Full=ATAC;
DE   AltName: Full=C motif chemokine 1;
DE   AltName: Full=Cytokine SCM-1;
DE   AltName: Full=Lymphotaxin;
DE   AltName: Full=SCM-1-alpha;
DE   AltName: Full=Small-inducible cytokine C1;
DE   AltName: Full=XC chemokine ligand 1;
DE   Flags: Precursor;
GN   Name=XCL1; Synonyms=LTN, SCYC1;
DR   GO; GO:0008009; F:chemokine activity; IDA:BHF-UCL.
DR   GO; GO:0042379; F:chemokine receptor binding; IDA:BHF-UCL.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.
DR   GO; GO:0007267; P:cell-cell signaling; IDA:BHF-UCL.
DR   GO; GO:0071353; P:cellular response to interleukin-4; ISS:BHF-UCL.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; ISS:BHF-UCL.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0035782; P:mature natural killer cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:2000562; P:negative regulation of CD4-positive, alpha-beta T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:0032689; P:negative regulation of interferon-gamma production; IDA:BHF-UCL.
DR   GO; GO:0032703; P:negative regulation of interleukin-2 production; IDA:BHF-UCL.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0002725; P:negative regulation of T cell cytokine production; IDA:BHF-UCL.
DR   GO; GO:2000518; P:negative regulation of T-helper 1 cell activation; IDA:BHF-UCL.
DR   GO; GO:0002826; P:negative regulation of T-helper 1 type immune response; IC:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
DR   GO; GO:0030593; P:neutrophil chemotaxis; TAS:BHF-UCL.
DR   GO; GO:2000538; P:positive regulation of B cell chemotaxis; ISS:BHF-UCL.
DR   GO; GO:2000563; P:positive regulation of CD4-positive, alpha-beta T cell proliferation; ISS:BHF-UCL.
DR   GO; GO:2000566; P:positive regulation of CD8-positive, alpha-beta T cell proliferation; IDA:BHF-UCL.
DR   GO; GO:2000513; P:positive regulation of granzyme A production; IDA:BHF-UCL.
DR   GO; GO:0071663; P:positive regulation of granzyme B production; IDA:BHF-UCL.
DR   GO; GO:2000558; P:positive regulation of immunoglobulin production in mucosal tissue; ISS:BHF-UCL.
DR   GO; GO:0032733; P:positive regulation of interleukin-10 production; IDA:BHF-UCL.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; ISS:BHF-UCL.
DR   GO; GO:2000503; P:positive regulation of natural killer cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:BHF-UCL.
DR   GO; GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; IDA:BHF-UCL.
DR   GO; GO:0010820; P:positive regulation of T cell chemotaxis; IDA:BHF-UCL.
DR   GO; GO:0002726; P:positive regulation of T cell cytokine production; ISS:BHF-UCL.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IDA:BHF-UCL.
DR   GO; GO:2000556; P:positive regulation of T-helper 1 cell cytokine production; ISS:BHF-UCL.
DR   GO; GO:2000553; P:positive regulation of T-helper 2 cell cytokine production; ISS:BHF-UCL.
DR   GO; GO:2000412; P:positive regulation of thymocyte migration; ISS:BHF-UCL.
DR   GO; GO:0071636; P:positive regulation of transforming growth factor beta production; IDA:BHF-UCL.
DR   GO; GO:0050727; P:regulation of inflammatory response; IDA:BHF-UCL.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:BHF-UCL.
DR   GO; GO:0009615; P:response to virus; IDA:BHF-UCL.
DR   GO; GO:0007165; P:signal transduction; IC:BHF-UCL.
//
ID   XCL2_HUMAN              Reviewed;         114 AA.
AC   Q9UBD3;
DE   RecName: Full=Cytokine SCM-1 beta;
DE   AltName: Full=C motif chemokine 2;
DE   AltName: Full=XC chemokine ligand 2;
DE   Flags: Precursor;
GN   Name=XCL2; Synonyms=SCYC2;
DR   GO; GO:0008009; F:chemokine activity; TAS:ProtInc.
DR   GO; GO:0008015; P:blood circulation; TAS:ProtInc.
DR   GO; GO:0060326; P:cell chemotaxis; TAS:GOC.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
//
ID   XCR1_HUMAN              Reviewed;         333 AA.
AC   P46094;
DE   RecName: Full=Chemokine XC receptor 1;
DE   AltName: Full=G-protein coupled receptor 5;
DE   AltName: Full=Lymphotactin receptor;
DE   AltName: Full=XC chemokine receptor 1;
GN   Name=XCR1; Synonyms=CCXCR1, GPR5;
DR   GuidetoPHARMACOLOGY; 75; -.
DR   GO; GO:0004950; F:chemokine receptor activity; TAS:ProtInc.
DR   GO; GO:0070098; P:chemokine-mediated signaling pathway; TAS:GOC.
DR   GO; GO:0006935; P:chemotaxis; TAS:ProtInc.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
DR   GO; GO:0007187; P:G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; TAS:ProtInc.
DR   GO; GO:0006954; P:inflammatory response; TAS:ProtInc.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; TAS:ProtInc.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IEA:Ensembl.
//
ID   XCT_HUMAN               Reviewed;         501 AA.
AC   Q9UPY5; A8K2U4;
DE   RecName: Full=Cystine/glutamate transporter;
DE   AltName: Full=Amino acid transport system xc-;
DE   AltName: Full=Calcium channel blocker resistance protein CCBR1;
DE   AltName: Full=Solute carrier family 7 member 11;
DE   AltName: Full=xCT;
GN   Name=SLC7A11;
DR   GO; GO:0015327; F:cystine:glutamate antiporter activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0015813; P:L-glutamate transport; TAS:GOC.
DR   GO; GO:0070306; P:lens fiber cell differentiation; IEA:Ensembl.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0070527; P:platelet aggregation; IEA:Ensembl.
DR   GO; GO:0035094; P:response to nicotine; IEA:Ensembl.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   XDH_HUMAN               Reviewed;        1333 AA.
AC   P47989; Q16681; Q16712; Q4PJ16;
DE   RecName: Full=Xanthine dehydrogenase/oxidase;
DE   Includes:
DE     RecName: Full=Xanthine dehydrogenase;
DE              Short=XD;
DE              EC=1.17.1.4;
DE   Includes:
DE     RecName: Full=Xanthine oxidase;
DE              Short=XO;
DE              EC=1.17.3.2;
DE     AltName: Full=Xanthine oxidoreductase;
DE              Short=XOR;
GN   Name=XDH; Synonyms=XDHA;
DR   GuidetoPHARMACOLOGY; 2646; -.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:UniProtKB.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IDA:UniProtKB.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0008762; F:UDP-N-acetylmuramate dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0004854; F:xanthine dehydrogenase activity; IDA:UniProtKB.
DR   GO; GO:0004855; F:xanthine oxidase activity; IDA:UniProtKB.
DR   GO; GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0007595; P:lactation; IEA:Ensembl.
DR   GO; GO:0045602; P:negative regulation of endothelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0001937; P:negative regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IDA:UniProtKB.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:1900747; P:negative regulation of vascular endothelial growth factor signaling pathway; IDA:UniProtKB.
DR   GO; GO:2001213; P:negative regulation of vasculogenesis; IDA:UniProtKB.
DR   GO; GO:0055086; P:nucleobase-containing small molecule metabolic process; TAS:Reactome.
DR   GO; GO:1900745; P:positive regulation of p38MAPK cascade; IDA:UniProtKB.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:UniProtKB.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; TAS:Reactome.
DR   GO; GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
DR   GO; GO:0009115; P:xanthine catabolic process; IDA:UniProtKB.
//
ID   XG_HUMAN                Reviewed;         180 AA.
AC   P55808; E9PCH1; Q496N8; Q496N9; Q496P0; Q71BZ5;
DE   RecName: Full=Glycoprotein Xg;
DE   AltName: Full=Protein PBDX;
DE   Flags: Precursor;
GN   Name=XG; Synonyms=PBDX;
//
ID   XIAP_HUMAN              Reviewed;         497 AA.
AC   P98170; D3DTF2; Q9NQ14;
DE   RecName: Full=E3 ubiquitin-protein ligase XIAP;
DE            EC=6.3.2.-;
DE   AltName: Full=Baculoviral IAP repeat-containing protein 4;
DE   AltName: Full=IAP-like protein;
DE            Short=ILP;
DE            Short=hILP;
DE   AltName: Full=Inhibitor of apoptosis protein 3;
DE            Short=IAP-3;
DE            Short=hIAP-3;
DE            Short=hIAP3;
DE   AltName: Full=X-linked inhibitor of apoptosis protein;
DE            Short=X-linked IAP;
GN   Name=XIAP; Synonyms=API3, BIRC4, IAP3;
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:UniProtKB.
DR   GO; GO:0055070; P:copper ion homeostasis; TAS:UniProtKB.
DR   GO; GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:Reactome.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:1902530; P:positive regulation of protein linear polyubiquitination; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:GOC.
DR   GO; GO:0030510; P:regulation of BMP signaling pathway; TAS:UniProtKB.
DR   GO; GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.
DR   GO; GO:0050727; P:regulation of inflammatory response; TAS:UniProtKB.
DR   GO; GO:0045088; P:regulation of innate immune response; TAS:UniProtKB.
DR   GO; GO:0070424; P:regulation of nucleotide-binding oligomerization domain containing signaling pathway; TAS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   XIRP1_HUMAN             Reviewed;        1843 AA.
AC   Q702N8; A0JP25; A4QPE2; Q68DF2; Q6ZTR3; Q702N9; Q8IVN7; Q8N1N3;
AC   Q8N904; Q8TCG7;
DE   RecName: Full=Xin actin-binding repeat-containing protein 1;
DE   AltName: Full=Cardiomyopathy-associated protein 1;
GN   Name=XIRP1; Synonyms=CMYA1, XIN;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0055013; P:cardiac muscle cell development; IEA:Ensembl.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0042391; P:regulation of membrane potential; IEA:Ensembl.
DR   GO; GO:0045214; P:sarcomere organization; IEA:Ensembl.
//
ID   XIRP2_HUMAN             Reviewed;        3374 AA.
AC   A4UGR9; A0PJ94; B2BBS0; B2BBS1; B2BBS4; B3KVH0; J3KNB1; Q53R52;
AC   Q5MJ67; Q702N7; Q86T36; Q86T38; Q86T46; Q86T51; Q86T53; Q86T55;
AC   Q86T79; Q86TB6; Q8N1M9; Q8N3R5; Q8TBV6;
DE   RecName: Full=Xin actin-binding repeat-containing protein 2;
DE   AltName: Full=Beta-xin;
DE   AltName: Full=Cardiomyopathy-associated protein 3;
DE   AltName: Full=Xeplin;
GN   Name=XIRP2; Synonyms=CMYA3;
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0055008; P:cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:0045216; P:cell-cell junction organization; IEA:Ensembl.
DR   GO; GO:0003281; P:ventricular septum development; IEA:Ensembl.
//
ID   XKR2_HUMAN              Reviewed;         449 AA.
AC   Q6PP77; B2RNN6; B4DKU2; Q5H9J6;
DE   RecName: Full=XK-related protein 2;
DE   AltName: Full=Membrane protein XPLAC;
DE   AltName: Full=X Kell blood group-related, X-linked;
GN   Name=XKRX; Synonyms=XKR2, XPLAC, XRG2;
//
ID   XKR3_HUMAN              Reviewed;         459 AA.
AC   Q5GH77; B2RPN1; Q52PG8; Q8N7E1;
DE   RecName: Full=XK-related protein 3;
DE   AltName: Full=X Kell blood group-related 3;
DE   AltName: Full=XTES;
GN   Name=XKR3; Synonyms=XRG3;
//
ID   XKR5_HUMAN              Reviewed;         686 AA.
AC   Q6UX68; Q5GH74;
DE   RecName: Full=XK-related protein 5;
GN   Name=XKR5; Synonyms=XRG5; ORFNames=UNQ2754/PRO6493;
//
ID   XKR4_HUMAN              Reviewed;         650 AA.
AC   Q5GH76; Q96PZ8;
DE   RecName: Full=XK-related protein 4;
GN   Name=XKR4; Synonyms=KIAA1889, XRG4;
//
ID   XKR6_HUMAN              Reviewed;         641 AA.
AC   Q5GH73; Q8TBA0;
DE   RecName: Full=XK-related protein 6;
GN   Name=XKR6; Synonyms=C8orf21, C8orf5, C8orf7, XRG6;
//
ID   XKR7_HUMAN              Reviewed;         579 AA.
AC   Q5GH72; Q9NUG5;
DE   RecName: Full=XK-related protein 7;
GN   Name=XKR7; Synonyms=C20orf159, XRG7;
//
ID   XKR8_HUMAN              Reviewed;         395 AA.
AC   Q9H6D3;
DE   RecName: Full=XK-related protein 8;
DE            Short=hXkr8;
DE   Contains:
DE     RecName: Full=XK-related protein 8, processed form;
GN   Name=XKR8; Synonyms=XRG8;
DR   GO; GO:0043652; P:engulfment of apoptotic cell; IDA:UniProtKB.
DR   GO; GO:0070782; P:phosphatidylserine exposure on apoptotic cell surface; IDA:UniProtKB.
//
ID   XKR9_HUMAN              Reviewed;         373 AA.
AC   Q5GH70; B2RNS9; B9EH74;
DE   RecName: Full=XK-related protein 9;
GN   Name=XKR9; Synonyms=XRG9;
//
ID   XKRY2_HUMAN             Reviewed;         117 AA.
AC   A2RUG3;
DE   RecName: Full=Testis-specific XK-related protein, Y-linked 2;
GN   Name=XKRY2;
//
ID   XKRY_HUMAN              Reviewed;         159 AA.
AC   O14609;
DE   RecName: Full=Testis-specific XK-related protein, Y-linked;
GN   Name=XKRY; Synonyms=XKRY1;
DR   GO; GO:0007338; P:single fertilization; TAS:ProtInc.
//
ID   XK_HUMAN                Reviewed;         444 AA.
AC   P51811; Q4TTN6; Q8IUK6; Q9UC77;
DE   RecName: Full=Membrane transport protein XK;
DE   AltName: Full=Kell complex 37 kDa component;
DE   AltName: Full=Kx antigen;
DE   AltName: Full=XK-related protein 1;
GN   Name=XK; Synonyms=XKR1, XRG1;
DR   GO; GO:0005515; F:protein binding; IPI:HGNC.
DR   GO; GO:0005215; F:transporter activity; TAS:ProtInc.
DR   GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   XLRS1_HUMAN             Reviewed;         224 AA.
AC   O15537; Q0QD39;
DE   RecName: Full=Retinoschisin;
DE   AltName: Full=X-linked juvenile retinoschisis protein;
DE   Flags: Precursor;
GN   Name=RS1; Synonyms=XLRS1;
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0070273; F:phosphatidylinositol-4-phosphate binding; IEA:Ensembl.
DR   GO; GO:0010314; F:phosphatidylinositol-5-phosphate binding; IEA:Ensembl.
DR   GO; GO:0001786; F:phosphatidylserine binding; IEA:Ensembl.
DR   GO; GO:0016062; P:adaptation of rhodopsin mediated signaling; IEA:Ensembl.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0010842; P:retina layer formation; IEA:Ensembl.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   XP32_HUMAN              Reviewed;         250 AA.
AC   Q5T750; O14634;
DE   RecName: Full=Skin-specific protein 32;
GN   Name=XP32; Synonyms=C1orf68;
DR   GO; GO:0008544; P:epidermis development; NAS:UniProtKB.
//
ID   XPA_HUMAN               Reviewed;         273 AA.
AC   P23025; Q5T1U9; Q6LCW7; Q6LD02;
DE   RecName: Full=DNA repair protein complementing XP-A cells;
DE   AltName: Full=Xeroderma pigmentosum group A-complementing protein;
GN   Name=XPA; Synonyms=XPAC;
DR   GO; GO:0003684; F:damaged DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:Ensembl.
DR   GO; GO:0009636; P:response to toxic substance; IEA:Ensembl.
DR   GO; GO:0009411; P:response to UV; IEA:Ensembl.
//
ID   XPC_HUMAN               Reviewed;         940 AA.
AC   Q01831; B4DIP3; E9PH69; Q53GT7; Q96AX0;
DE   RecName: Full=DNA repair protein complementing XP-C cells;
DE   AltName: Full=Xeroderma pigmentosum group C-complementing protein;
DE   AltName: Full=p125;
GN   Name=XPC; Synonyms=XPCC;
DR   GO; GO:0000405; F:bubble DNA binding; TAS:UniProtKB.
DR   GO; GO:0003684; F:damaged DNA binding; IDA:UniProtKB.
DR   GO; GO:0000404; F:heteroduplex DNA loop binding; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0031573; P:intra-S DNA damage checkpoint; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.
DR   GO; GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:UniProtKB.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:1901990; P:regulation of mitotic cell cycle phase transition; IMP:UniProtKB.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0010224; P:response to UV-B; IEA:Ensembl.
//
ID   XPF_HUMAN               Reviewed;         916 AA.
AC   Q92889; A8K111; O00140; Q8TD83;
DE   RecName: Full=DNA repair endonuclease XPF;
DE            EC=3.1.-.-;
DE   AltName: Full=DNA excision repair protein ERCC-4;
DE   AltName: Full=DNA repair protein complementing XP-F cells;
DE   AltName: Full=Xeroderma pigmentosum group F-complementing protein;
GN   Name=ERCC4; Synonyms=ERCC11, XPF;
DR   GO; GO:0003684; F:damaged DNA binding; IMP:UniProtKB.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
DR   GO; GO:0000014; F:single-stranded DNA endodeoxyribonuclease activity; IBA:RefGenome.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.
DR   GO; GO:0032205; P:negative regulation of telomere maintenance; IMP:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; IMP:UniProtKB.
DR   GO; GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.
DR   GO; GO:0033683; P:nucleotide-excision repair, DNA incision; IDA:UniProtKB.
DR   GO; GO:0006295; P:nucleotide-excision repair, DNA incision, 3'-to lesion; IMP:UniProtKB.
DR   GO; GO:0006296; P:nucleotide-excision repair, DNA incision, 5'-to lesion; IMP:UniProtKB.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IBA:RefGenome.
DR   GO; GO:0009411; P:response to UV; IMP:UniProtKB.
DR   GO; GO:0000723; P:telomere maintenance; IMP:BHF-UCL.
DR   GO; GO:0010834; P:telomere maintenance via telomere shortening; IMP:BHF-UCL.
DR   GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; TAS:Reactome.
DR   GO; GO:0009650; P:UV protection; IEA:Ensembl.
//
ID   XPO1_HUMAN              Reviewed;        1071 AA.
AC   O14980; A6NL14; A8K1K5; D6W5E2; Q63HP8; Q68CP3; Q99433;
DE   RecName: Full=Exportin-1;
DE            Short=Exp1;
DE   AltName: Full=Chromosome region maintenance 1 protein homolog;
GN   Name=XPO1; Synonyms=CRM1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005215; F:transporter activity; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0075733; P:intracellular transport of virus; TAS:Reactome.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
DR   GO; GO:0042176; P:regulation of protein catabolic process; IEA:Ensembl.
DR   GO; GO:0046825; P:regulation of protein export from nucleus; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0019058; P:viral life cycle; TAS:Reactome.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   XPO2_HUMAN              Reviewed;         971 AA.
AC   P55060; A3RLL6; B2R5T4; E1P5Y0; F8W904; O75432; Q32M40; Q9H5B7;
AC   Q9NTS0; Q9UP98; Q9UP99; Q9UPA0;
DE   RecName: Full=Exportin-2;
DE            Short=Exp2;
DE   AltName: Full=Cellular apoptosis susceptibility protein;
DE   AltName: Full=Chromosome segregation 1-like protein;
DE   AltName: Full=Importin-alpha re-exporter;
GN   Name=CSE1L; Synonyms=CAS, XPO2;
DR   GO; GO:0008262; F:importin-alpha export receptor activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0006611; P:protein export from nucleus; TAS:GOC.
//
ID   XPO4_HUMAN              Reviewed;        1151 AA.
AC   Q9C0E2; Q5VUZ5; Q8N3V6; Q9H934;
DE   RecName: Full=Exportin-4;
DE            Short=Exp4;
GN   Name=XPO4; Synonyms=KIAA1721;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046827; P:positive regulation of protein export from nucleus; IMP:BHF-UCL.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
//
ID   XPO5_HUMAN              Reviewed;        1204 AA.
AC   Q9HAV4; Q5JTE6; Q96G48; Q96HN3; Q9BWM6; Q9BZV5; Q9H9M4; Q9NT89;
AC   Q9NW39; Q9ULC9;
DE   RecName: Full=Exportin-5;
DE            Short=Exp5;
DE   AltName: Full=Ran-binding protein 21;
GN   Name=XPO5; Synonyms=KIAA1291, RANBP21;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IEA:Ensembl.
DR   GO; GO:0003723; F:RNA binding; TAS:Reactome.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:Ensembl.
//
ID   XPO6_HUMAN              Reviewed;        1125 AA.
AC   Q96QU8; A1L3W4; Q2YDX3; Q53G88; Q68G50; Q76N88; Q96CP8; Q9BT21;
DE   RecName: Full=Exportin-6;
DE            Short=Exp6;
DE   AltName: Full=Ran-binding protein 20;
GN   Name=XPO6; Synonyms=KIAA0370, RANBP20;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IDA:UniProtKB.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
//
ID   XPO7_HUMAN              Reviewed;        1087 AA.
AC   Q9UIA9; O94846; Q6PJK9; Q8NEK7;
DE   RecName: Full=Exportin-7;
DE            Short=Exp7;
DE   AltName: Full=Ran-binding protein 16;
GN   Name=XPO7; Synonyms=KIAA0745, RANBP16;
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IDA:UniProtKB.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0006611; P:protein export from nucleus; IDA:UniProtKB.
//
ID   XPOT_HUMAN              Reviewed;         962 AA.
AC   O43592; A6NLH1; O43784; Q8WUG2; Q9BVS7;
DE   RecName: Full=Exportin-T;
DE   AltName: Full=Exportin(tRNA);
DE   AltName: Full=tRNA exportin;
GN   Name=XPOT;
DR   GO; GO:0000049; F:tRNA binding; IDA:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0006409; P:tRNA export from nucleus; IDA:UniProtKB.
//
ID   XPP1_HUMAN              Reviewed;         623 AA.
AC   Q9NQW7; A8K071; G5E9Y2; O15250; Q53EX6; Q8N3Q0; Q96D23;
DE   RecName: Full=Xaa-Pro aminopeptidase 1;
DE            EC=3.4.11.9;
DE   AltName: Full=Aminoacylproline aminopeptidase;
DE   AltName: Full=Cytosolic aminopeptidase P;
DE   AltName: Full=Soluble aminopeptidase P;
DE            Short=sAmp;
DE   AltName: Full=X-Pro aminopeptidase 1;
DE   AltName: Full=X-prolyl aminopeptidase 1, soluble;
GN   Name=XPNPEP1; Synonyms=XPNPEPL, XPNPEPL1;
DR   GO; GO:0004177; F:aminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0030145; F:manganese ion binding; IDA:UniProtKB.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0010815; P:bradykinin catabolic process; IDA:UniProtKB.
DR   GO; GO:0006508; P:proteolysis; IDA:UniProtKB.
//
ID   XPP2_HUMAN              Reviewed;         674 AA.
AC   O43895; A0AV16; O75994;
DE   RecName: Full=Xaa-Pro aminopeptidase 2;
DE            EC=3.4.11.9;
DE   AltName: Full=Aminoacylproline aminopeptidase;
DE   AltName: Full=Membrane-bound aminopeptidase P;
DE            Short=Membrane-bound APP;
DE            Short=Membrane-bound AmP;
DE            Short=mAmP;
DE   AltName: Full=X-Pro aminopeptidase 2;
DE   Flags: Precursor;
GN   Name=XPNPEP2;
DR   GO; GO:0004177; F:aminopeptidase activity; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
//
ID   XPP3_HUMAN              Reviewed;         507 AA.
AC   Q9NQH7; B2R9G1; B7Z790; B7Z7B2; Q6I9V9; Q8NDA6; Q9BV27; Q9BVH0;
DE   RecName: Full=Probable Xaa-Pro aminopeptidase 3;
DE            Short=X-Pro aminopeptidase 3;
DE            EC=3.4.11.9;
DE   AltName: Full=Aminopeptidase P3;
DE            Short=APP3;
GN   Name=XPNPEP3;
DR   GO; GO:0004177; F:aminopeptidase activity; IMP:MGI.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003094; P:glomerular filtration; IMP:MGI.
DR   GO; GO:0016485; P:protein processing; IMP:MGI.
//
ID   XPR1_HUMAN              Reviewed;         696 AA.
AC   Q9UBH6; O95719; Q7L8K9; Q8IW20; Q9NT19; Q9UFB9;
DE   RecName: Full=Xenotropic and polytropic retrovirus receptor 1;
DE   AltName: Full=Protein SYG1 homolog;
DE   AltName: Full=Xenotropic and polytropic murine leukemia virus receptor X3;
DE            Short=X-receptor;
GN   Name=XPR1; Synonyms=SYG1, XR;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; TAS:ProtInc.
DR   GO; GO:0004872; F:receptor activity; TAS:ProtInc.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
DR   GO; GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
//
ID   XRCC1_HUMAN             Reviewed;         633 AA.
AC   P18887; Q6IBS4; Q9HCB1;
DE   RecName: Full=DNA repair protein XRCC1;
DE   AltName: Full=X-ray repair cross-complementing protein 1;
GN   Name=XRCC1;
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006284; P:base-excision repair; TAS:Reactome.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
DR   GO; GO:0000012; P:single strand break repair; IEA:InterPro.
//
ID   XRCC2_HUMAN             Reviewed;         280 AA.
AC   O43543; B2R925;
DE   RecName: Full=DNA repair protein XRCC2;
DE   AltName: Full=X-ray repair cross-complementing protein 2;
GN   Name=XRCC2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0051297; P:centrosome organization; IMP:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; IGI:BHF-UCL.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IEA:Ensembl.
DR   GO; GO:0042148; P:strand invasion; IDA:UniProtKB.
//
ID   XRCC3_HUMAN             Reviewed;         346 AA.
AC   O43542; O43568; Q9BU18;
DE   RecName: Full=DNA repair protein XRCC3;
DE   AltName: Full=X-ray repair cross-complementing protein 3;
GN   Name=XRCC3;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008094; F:DNA-dependent ATPase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; TAS:ProtInc.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IMP:GOC.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; IGI:BHF-UCL.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0090267; P:positive regulation of mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB.
DR   GO; GO:0071140; P:resolution of mitotic recombination intermediates; IMP:UniProtKB.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
//
ID   XRCC4_HUMAN             Reviewed;         336 AA.
AC   Q13426; A8K3X4; Q9BS72; Q9UP94;
DE   RecName: Full=DNA repair protein XRCC4;
DE   AltName: Full=X-ray repair cross-complementing protein 4;
GN   Name=XRCC4;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0071285; P:cellular response to lithium ion; IEA:Ensembl.
DR   GO; GO:0007417; P:central nervous system development; IEA:Ensembl.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IDA:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; IDA:UniProtKB.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IDA:UniProtKB.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0033152; P:immunoglobulin V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0045190; P:isotype switching; IEA:Ensembl.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0051351; P:positive regulation of ligase activity; IDA:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0002328; P:pro-B cell differentiation; IEA:Ensembl.
DR   GO; GO:0010332; P:response to gamma radiation; IEA:Ensembl.
DR   GO; GO:0010165; P:response to X-ray; IDA:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   XRCC5_HUMAN             Reviewed;         732 AA.
AC   P13010; A8K3X5; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1;
DE   RecName: Full=X-ray repair cross-complementing protein 5;
DE            EC=3.6.4.-;
DE   AltName: Full=86 kDa subunit of Ku antigen;
DE   AltName: Full=ATP-dependent DNA helicase 2 subunit 2;
DE   AltName: Full=ATP-dependent DNA helicase II 80 kDa subunit;
DE   AltName: Full=CTC box-binding factor 85 kDa subunit;
DE            Short=CTC85;
DE            Short=CTCBF;
DE   AltName: Full=DNA repair protein XRCC5;
DE   AltName: Full=Ku80;
DE   AltName: Full=Ku86;
DE   AltName: Full=Lupus Ku autoantigen protein p86;
DE   AltName: Full=Nuclear factor IV;
DE   AltName: Full=Thyroid-lupus autoantigen;
DE            Short=TLAA;
DE   AltName: Full=X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining);
GN   Name=XRCC5; Synonyms=G22P2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; IDA:BHF-UCL.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; IEA:Ensembl.
DR   GO; GO:0071475; P:cellular hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0071398; P:cellular response to fatty acid; IEA:Ensembl.
DR   GO; GO:0071481; P:cellular response to X-ray; IEA:Ensembl.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006310; P:DNA recombination; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0060218; P:hematopoietic stem cell differentiation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0000723; P:telomere maintenance; TAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   XRCC6_HUMAN             Reviewed;         609 AA.
AC   P12956; Q6FG89; Q9UCQ2; Q9UCQ3;
DE   RecName: Full=X-ray repair cross-complementing protein 6;
DE            EC=3.6.4.-;
DE            EC=4.2.99.-;
DE   AltName: Full=5'-deoxyribose-5-phosphate lyase Ku70;
DE            Short=5'-dRP lyase Ku70;
DE   AltName: Full=70 kDa subunit of Ku antigen;
DE   AltName: Full=ATP-dependent DNA helicase 2 subunit 1;
DE   AltName: Full=ATP-dependent DNA helicase II 70 kDa subunit;
DE   AltName: Full=CTC box-binding factor 75 kDa subunit;
DE            Short=CTC75;
DE            Short=CTCBF;
DE   AltName: Full=DNA repair protein XRCC6;
DE   AltName: Full=Lupus Ku autoantigen protein p70;
DE            Short=Ku70;
DE   AltName: Full=Thyroid-lupus autoantigen;
DE            Short=TLAA;
DE   AltName: Full=X-ray repair complementing defective repair in Chinese hamster cells 6;
GN   Name=XRCC6; Synonyms=G22P1;
DR   GO; GO:0051575; F:5'-deoxyribose-5-phosphate lyase activity; IMP:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; TAS:ProtInc.
DR   GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0042162; F:telomeric DNA binding; IEA:InterPro.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0071475; P:cellular hyperosmotic salinity response; IEA:Ensembl.
DR   GO; GO:0071481; P:cellular response to X-ray; IEA:Ensembl.
DR   GO; GO:0032508; P:DNA duplex unwinding; TAS:GOC.
DR   GO; GO:0006266; P:DNA ligation; TAS:ProtInc.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0006302; P:double-strand break repair; TAS:Reactome.
DR   GO; GO:0006303; P:double-strand break repair via nonhomologous end joining; IMP:UniProtKB.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; TAS:Reactome.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0000723; P:telomere maintenance; TAS:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0033151; P:V(D)J recombination; IEA:Ensembl.
DR   GO; GO:0016032; P:viral process; TAS:Reactome.
//
ID   XRN1_HUMAN              Reviewed;        1706 AA.
AC   Q8IZH2; Q4G0S3; Q68D88; Q6AI24; Q6MZS8; Q86WS7; Q8N8U4; Q9UF39;
DE   RecName: Full=5'-3' exoribonuclease 1;
DE            EC=3.1.13.-;
DE   AltName: Full=Strand-exchange protein 1 homolog;
GN   Name=XRN1; Synonyms=SEP1;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0016071; P:mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0071028; P:nuclear mRNA surveillance; IMP:UniProtKB.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; TAS:Reactome.
DR   GO; GO:0016070; P:RNA metabolic process; TAS:Reactome.
DR   GO; GO:0016075; P:rRNA catabolic process; IMP:UniProtKB.
//
ID   XRN2_HUMAN              Reviewed;         950 AA.
AC   Q9H0D6; Q3L8N4; Q6KGZ9; Q9BQL1; Q9NTW0; Q9NXS6; Q9UL53;
DE   RecName: Full=5'-3' exoribonuclease 2;
DE            EC=3.1.13.-;
DE   AltName: Full=DHM1-like protein;
DE            Short=DHP protein;
GN   Name=XRN2;
DR   GO; GO:0008409; F:5'-3' exonuclease activity; IDA:UniProtKB.
DR   GO; GO:0004534; F:5'-3' exoribonuclease activity; TAS:UniProtKB.
DR   GO; GO:0004518; F:nuclease activity; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016049; P:cell growth; ISS:UniProtKB.
DR   GO; GO:0000738; P:DNA catabolic process, exonucleolytic; IDA:UniProtKB.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006401; P:RNA catabolic process; TAS:ProtInc.
DR   GO; GO:0016070; P:RNA metabolic process; ISS:UniProtKB.
DR   GO; GO:0090503; P:RNA phosphodiester bond hydrolysis, exonucleolytic; TAS:GOC.
DR   GO; GO:0006396; P:RNA processing; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEP:UniProtKB.
//
ID   XRP2_HUMAN              Reviewed;         350 AA.
AC   O75695; Q86XJ7; Q9NU67;
DE   RecName: Full=Protein XRP2;
GN   Name=RP2;
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005096; F:GTPase activator activity; IDA:UniProtKB.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051082; F:unfolded protein binding; TAS:ProtInc.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0043547; P:positive regulation of GTPase activity; IDA:GOC.
DR   GO; GO:0006892; P:post-Golgi vesicle-mediated transport; IMP:MGI.
DR   GO; GO:0006457; P:protein folding; TAS:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; TAS:ProtInc.
//
ID   XRRA1_HUMAN             Reviewed;         792 AA.
AC   Q6P2D8; B5MD90; J3KNJ1; Q7RTT7; Q7Z463; Q7Z4U0;
DE   RecName: Full=X-ray radiation resistance-associated protein 1;
GN   Name=XRRA1;
DR   GO; GO:0010165; P:response to X-ray; IDA:UniProtKB.
//
ID   XXLT1_HUMAN             Reviewed;         393 AA.
AC   Q8NBI6; D3DNW5; Q8NAL3; Q8WV03; Q96ME0;
DE   RecName: Full=Xyloside xylosyltransferase 1;
DE            EC=2.4.2.n3;
DE   AltName: Full=UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase;
GN   Name=XXYLT1; Synonyms=C3orf21; ORFNames=PSEC0251;
DR   GO; GO:0016763; F:transferase activity, transferring pentosyl groups; IEA:UniProtKB-EC.
//
ID   XYLB_HUMAN              Reviewed;         536 AA.
AC   O75191; B2RAW4; B9EH64;
DE   RecName: Full=Xylulose kinase;
DE            Short=Xylulokinase;
DE            EC=2.7.1.17;
GN   Name=XYLB;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004856; F:xylulokinase activity; IDA:UniProtKB.
DR   GO; GO:0005975; P:carbohydrate metabolic process; TAS:ProtInc.
DR   GO; GO:0046835; P:carbohydrate phosphorylation; IDA:GOC.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006091; P:generation of precursor metabolites and energy; TAS:ProtInc.
DR   GO; GO:0005998; P:xylulose catabolic process; TAS:BHF-UCL.
DR   GO; GO:0005997; P:xylulose metabolic process; IDA:UniProtKB.
//
ID   XYLK_HUMAN              Reviewed;         409 AA.
AC   O75063; Q5W0C3; Q5W0C4;
DE   RecName: Full=Glycosaminoglycan xylosylkinase;
DE            EC=2.7.1.-;
DE   AltName: Full=Protein FAM20B;
DE   AltName: Full=Xylose kinase;
GN   Name=FAM20B; Synonyms=KIAA0475;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IDA:UniProtKB.
//
ID   XYLT1_HUMAN             Reviewed;         959 AA.
AC   Q86Y38; Q9H1B6;
DE   RecName: Full=Xylosyltransferase 1;
DE            EC=2.4.2.26;
DE   AltName: Full=Peptide O-xylosyltransferase 1;
DE   AltName: Full=Xylosyltransferase I;
DE            Short=XT-I;
DE            Short=XylT-I;
GN   Name=XYLT1; Synonyms=XT1;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IEA:InterPro.
DR   GO; GO:0030158; F:protein xylosyltransferase activity; TAS:UniProtKB.
DR   GO; GO:0034605; P:cellular response to heat; IEA:Ensembl.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; TAS:UniProtKB.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   XYLT2_HUMAN             Reviewed;         865 AA.
AC   Q9H1B5; Q6UY41; Q86V00;
DE   RecName: Full=Xylosyltransferase 2;
DE            EC=2.4.2.26;
DE   AltName: Full=Peptide O-xylosyltransferase 1;
DE   AltName: Full=Xylosyltransferase II;
DE            Short=XT-II;
DE            Short=XylT-II;
GN   Name=XYLT2; Synonyms=XT2; ORFNames=UNQ3058/PRO9878;
DR   GO; GO:0008375; F:acetylglucosaminyltransferase activity; IEA:InterPro.
DR   GO; GO:0030158; F:protein xylosyltransferase activity; NAS:UniProtKB.
DR   GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006024; P:glycosaminoglycan biosynthetic process; NAS:UniProtKB.
DR   GO; GO:0015012; P:heparan sulfate proteoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
//
ID   YA011_HUMAN             Reviewed;         107 AA.
AC   Q6XCG6;
DE   RecName: Full=Putative uncharacterized protein PP632;
GN   ORFNames=PP632;
//
ID   YA021_HUMAN             Reviewed;         233 AA.
AC   Q6ZU45;
DE   RecName: Full=Putative C-type lectin domain-containing protein LINC00083;
GN   Name=LINC00083; Synonyms=NCRNA00083;
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
//
ID   YA014_HUMAN             Reviewed;         153 AA.
AC   Q6ZRH3;
DE   RecName: Full=Putative uncharacterized protein FLJ46360;
//
ID   YA023_HUMAN             Reviewed;         263 AA.
AC   Q8NF67;
DE   RecName: Full=Putative uncharacterized protein FLJ00310;
//
ID   YA026_HUMAN             Reviewed;         169 AA.
AC   Q8N9X3;
DE   RecName: Full=Putative uncharacterized protein FLJ36116;
//
ID   YA028_HUMAN             Reviewed;         131 AA.
AC   Q8N9I1;
DE   RecName: Full=Putative uncharacterized protein FLJ37107;
//
ID   YA034_HUMAN             Reviewed;         341 AA.
AC   A8MUI8;
DE   RecName: Full=Putative UPF0607 protein ENSP00000383783;
//
ID   YA037_HUMAN             Reviewed;          79 AA.
AC   Q0P140;
DE   RecName: Full=Putative uncharacterized protein HSD52;
GN   ORFNames=HSD52;
//
ID   YA043_HUMAN             Reviewed;         218 AA.
AC   Q7L0L9;
DE   RecName: Full=Transmembrane protein LOC653160;
//
ID   YA044_HUMAN             Reviewed;         241 AA.
AC   M0R1G4;
DE   RecName: Full=Uncharacterized protein ENSP00000471857;
DR   GO; GO:0001578; P:microtubule bundle formation; IEA:Ensembl.
DR   GO; GO:0001764; P:neuron migration; IEA:Ensembl.
//
ID   YAED1_HUMAN             Reviewed;         226 AA.
AC   Q9NRH1; A4D1W4; Q6IAF7; Q8WVZ5;
DE   RecName: Full=Yae1 domain-containing protein 1;
GN   Name=YAE1D1; Synonyms=C7orf36; ORFNames=GK003;
//
ID   YAF2_HUMAN              Reviewed;         180 AA.
AC   Q8IY57; A8K5P0; B4DFU3; G3V465; Q99710;
DE   RecName: Full=YY1-associated factor 2;
GN   Name=YAF2;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   YAP1_HUMAN              Reviewed;         504 AA.
AC   P46937; B4DTY1; B7ZA01; E3WEB5; E3WEB6; E9PRV2; F5H202; K0KQ18;
AC   K0KYZ8; K0L195; K0L1G3; Q7Z574; Q8IUY9;
DE   RecName: Full=Yorkie homolog;
DE   AltName: Full=65 kDa Yes-associated protein;
DE            Short=YAP65;
GN   Name=YAP1; Synonyms=YAP65;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; IDA:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0071480; P:cellular response to gamma radiation; IDA:UniProtKB.
DR   GO; GO:0060242; P:contact inhibition; IDA:UniProtKB.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; IEA:Ensembl.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; TAS:UniProtKB.
DR   GO; GO:0030216; P:keratinocyte differentiation; IEA:Ensembl.
DR   GO; GO:0048368; P:lateral mesoderm development; IEA:Ensembl.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
DR   GO; GO:0030903; P:notochord development; IEA:Ensembl.
DR   GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010837; P:regulation of keratinocyte proliferation; IEA:Ensembl.
DR   GO; GO:0072091; P:regulation of stem cell proliferation; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
//
ID   YB004_HUMAN             Reviewed;         113 AA.
AC   Q6UWF6;
DE   RecName: Full=Putative uncharacterized protein UNQ3029/PRO9830;
DE   Flags: Precursor;
GN   ORFNames=UNQ3029/PRO9830;
//
ID   YB003_HUMAN             Reviewed;          95 AA.
AC   Q6UY13; Q6UWL7;
DE   RecName: Full=Putative uncharacterized protein UNQ5830/PRO19650/PRO19816;
DE   Flags: Precursor;
GN   ORFNames=UNQ5830/PRO19650/PRO19816;
//
ID   YB025_HUMAN             Reviewed;         131 AA.
AC   Q6ZU82; A6NMP0;
DE   RecName: Full=Putative inactive fatty acyl-CoA reductase 2-like protein FLJ43933;
DR   GO; GO:0080019; F:fatty-acyl-CoA reductase (alcohol-forming) activity; IEA:InterPro.
//
ID   YB011_HUMAN             Reviewed;         516 AA.
AC   Q6ZRH9;
DE   RecName: Full=Uncharacterized protein FLJ46347;
//
ID   YB049_HUMAN             Reviewed;         180 AA.
AC   Q86TA4;
DE   RecName: Full=Putative uncharacterized protein FLJ44553;
//
ID   YB043_HUMAN             Reviewed;          85 AA.
AC   A8MTW9;
DE   RecName: Full=Putative uncharacterized protein ENSP00000380674;
DE   Flags: Precursor;
//
ID   YB052_HUMAN             Reviewed;         120 AA.
AC   P0C867;
DE   RecName: Full=Putative uncharacterized protein LOC100130201;
//
ID   YB039_HUMAN             Reviewed;         138 AA.
AC   Q8NCU8;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00116;
GN   Name=LINC00116; Synonyms=NCRNA00116;
//
ID   YB057_HUMAN             Reviewed;         341 AA.
AC   A8MUA0;
DE   RecName: Full=Putative UPF0607 protein ENSP00000381514;
//
ID   YB035_HUMAN             Reviewed;         174 AA.
AC   Q8N2B8; Q2NKN5;
DE   RecName: Full=Putative uncharacterized protein FLJ33534;
//
ID   YBEY_HUMAN              Reviewed;         167 AA.
AC   P58557; B7WPA9; B7WPF7; D3DSN2;
DE   RecName: Full=Putative ribonuclease;
GN   Name=YBEY; Synonyms=C21orf57;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
//
ID   YBOX1_HUMAN             Reviewed;         324 AA.
AC   P67809; P16990; P16991; Q14972; Q15325; Q5FVF0;
DE   RecName: Full=Nuclease-sensitive element-binding protein 1;
DE   AltName: Full=CCAAT-binding transcription factor I subunit A;
DE            Short=CBF-A;
DE   AltName: Full=DNA-binding protein B;
DE            Short=DBPB;
DE   AltName: Full=Enhancer factor I subunit A;
DE            Short=EFI-A;
DE   AltName: Full=Y-box transcription factor;
DE   AltName: Full=Y-box-binding protein 1;
DE            Short=YB-1;
GN   Name=YBX1; Synonyms=NSEP1, YB1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0070934; P:CRD-mediated mRNA stabilization; IMP:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; TAS:Reactome.
DR   GO; GO:0051154; P:negative regulation of striated muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   YBOX2_HUMAN             Reviewed;         364 AA.
AC   Q9Y2T7; D3DTP1; Q8N4P0;
DE   RecName: Full=Y-box-binding protein 2;
DE   AltName: Full=Contrin;
DE   AltName: Full=DNA-binding protein C;
DE            Short=Dbpc;
DE   AltName: Full=Germ cell-specific Y-box-binding protein;
DE   AltName: Full=MSY2 homolog;
GN   Name=YBX2; Synonyms=CSDA3, MSY2;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008289; F:lipid binding; IEA:Ensembl.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:Ensembl.
DR   GO; GO:0045182; F:translation regulator activity; IEA:Ensembl.
DR   GO; GO:0048255; P:mRNA stabilization; IEA:Ensembl.
DR   GO; GO:0051100; P:negative regulation of binding; IEA:Ensembl.
DR   GO; GO:0017148; P:negative regulation of translation; IEA:Ensembl.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0009386; P:translational attenuation; TAS:ProtInc.
//
ID   YBOX3_HUMAN             Reviewed;         372 AA.
AC   P16989; B2RBW6; Q14121; Q969N6; Q96B76;
DE   RecName: Full=Y-box-binding protein 3;
DE   AltName: Full=Cold shock domain-containing protein A;
DE   AltName: Full=DNA-binding protein A;
DE   AltName: Full=Single-strand DNA-binding protein NF-GMB;
GN   Name=YBX3; Synonyms=CSDA, DBPA;
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; ISS:BHF-UCL.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0017048; F:Rho GTPase binding; ISS:BHF-UCL.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0070935; P:3'-UTR-mediated mRNA stabilization; IC:BHF-UCL.
DR   GO; GO:0071474; P:cellular hyperosmotic response; IMP:BHF-UCL.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:1902219; P:negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress; IMP:BHF-UCL.
DR   GO; GO:0060546; P:negative regulation of necroptotic process; IMP:BHF-UCL.
DR   GO; GO:0048642; P:negative regulation of skeletal muscle tissue development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:2000767; P:positive regulation of cytoplasmic translation; ISS:BHF-UCL.
DR   GO; GO:0046622; P:positive regulation of organ growth; IEA:Ensembl.
DR   GO; GO:0009409; P:response to cold; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   YC002_HUMAN             Reviewed;         168 AA.
AC   Q6UXU1;
DE   RecName: Full=Putative uncharacterized protein UNQ6490/PRO21339;
DE   Flags: Precursor;
GN   ORFNames=UNQ6490/PRO21339;
//
ID   YC006_HUMAN             Reviewed;         572 AA.
AC   Q6ZUG5;
DE   RecName: Full=Uncharacterized protein FLJ43738;
//
ID   YC003_HUMAN             Reviewed;         108 AA.
AC   Q6UXQ6;
DE   RecName: Full=Putative uncharacterized protein UNQ6125/PRO20090;
DE   Flags: Precursor;
GN   ORFNames=UNQ6125/PRO20090;
//
ID   YC014_HUMAN             Reviewed;          40 AA.
AC   Q05BU3; Q8IW37;
DE   RecName: Full=Putative uncharacterized protein LOC100125556;
//
ID   YC018_HUMAN             Reviewed;         199 AA.
AC   Q1RN00;
DE   RecName: Full=Putative uncharacterized protein LOC151760;
//
ID   YC023_HUMAN             Reviewed;          95 AA.
AC   Q0VG73; Q0VG74;
DE   RecName: Full=Putative uncharacterized protein LOC152225;
//
ID   YD018_HUMAN             Reviewed;         135 AA.
AC   Q9H8V8;
DE   RecName: Full=Putative uncharacterized protein FLJ13197;
//
ID   YD019_HUMAN             Reviewed;         223 AA.
AC   Q6ZRP5;
DE   RecName: Full=Putative uncharacterized protein FLJ46204;
//
ID   YD021_HUMAN             Reviewed;         634 AA.
AC   A8MVM7;
DE   RecName: Full=Putative uncharacterized protein ENSP00000382790;
//
ID   YD023_HUMAN             Reviewed;         140 AA.
AC   Q6ZQT0;
DE   RecName: Full=Putative uncharacterized protein FLJ45035;
//
ID   YD022_HUMAN             Reviewed;         163 AA.
AC   Q6ZS92;
DE   RecName: Full=Putative uncharacterized protein FLJ45721;
//
ID   YD286_HUMAN             Reviewed;         138 AA.
AC   A6NC05; G3V557;
DE   RecName: Full=Glutaredoxin-like protein C5orf63;
GN   Name=C5orf63;
DR   GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW.
//
ID   YDJC_HUMAN              Reviewed;         323 AA.
AC   A8MPS7; Q2YDT4; Q4V9R7;
DE   RecName: Full=UPF0249 protein ydjC homolog;
GN   Name=YDJC;
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
//
ID   YE014_HUMAN             Reviewed;          69 AA.
AC   Q9UI72;
DE   RecName: Full=Putative uncharacterized protein PRO0255;
GN   ORFNames=PRO0255;
//
ID   YE016_HUMAN             Reviewed;         198 AA.
AC   A6NLC8;
DE   RecName: Full=Putative TAF11-like protein ENSP00000332601;
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro.
//
ID   YE027_HUMAN             Reviewed;         180 AA.
AC   Q8NA96;
DE   RecName: Full=Putative uncharacterized protein FLJ35723;
//
ID   YES_HUMAN               Reviewed;         543 AA.
AC   P07947; A6NLB3; D3DUH1;
DE   RecName: Full=Tyrosine-protein kinase Yes;
DE            EC=2.7.10.2;
DE   AltName: Full=Proto-oncogene c-Yes;
DE   AltName: Full=p61-Yes;
GN   Name=YES1; Synonyms=YES;
DR   GuidetoPHARMACOLOGY; 2284; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0044325; F:ion channel binding; IPI:BHF-UCL.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; EXP:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006464; P:cellular protein modification process; TAS:ProtInc.
DR   GO; GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
DR   GO; GO:0015758; P:glucose transport; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; EXP:GOC.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0043114; P:regulation of vascular permeability; TAS:BHF-UCL.
DR   GO; GO:0031295; P:T cell costimulation; TAS:Reactome.
//
ID   YETS2_HUMAN             Reviewed;        1422 AA.
AC   Q9ULM3; A7E2B9; D3DNS9; Q641P6; Q9NW96;
DE   RecName: Full=YEATS domain-containing protein 2;
GN   Name=YEATS2; Synonyms=KIAA1197;
DR   GO; GO:0005515; F:protein binding; IPI:BHF-UCL.
DR   GO; GO:0017025; F:TBP-class protein binding; IPI:BHF-UCL.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:BHF-UCL.
//
ID   YETS4_HUMAN             Reviewed;         227 AA.
AC   O95619; Q9NQD0;
DE   RecName: Full=YEATS domain-containing protein 4;
DE   AltName: Full=Glioma-amplified sequence 41;
DE            Short=Gas41;
DE   AltName: Full=NuMA-binding protein 1;
DE            Short=NuBI-1;
DE            Short=NuBI1;
GN   Name=YEATS4; Synonyms=GAS41;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0005200; F:structural constituent of cytoskeleton; NAS:UniProtKB.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.
DR   GO; GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.
DR   GO; GO:0007067; P:mitosis; NAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   YF001_HUMAN             Reviewed;         172 AA.
AC   Q8N1X5;
DE   RecName: Full=Uncharacterized protein FLJ37310;
//
ID   YF006_HUMAN             Reviewed;         234 AA.
AC   Q8N9P0;
DE   RecName: Full=Putative uncharacterized protein FLJ36797;
//
ID   YF002_HUMAN             Reviewed;         114 AA.
AC   Q6UWF5;
DE   RecName: Full=Putative uncharacterized protein UNQ5815/PRO19632;
GN   ORFNames=UNQ5815/PRO19632;
//
ID   YF010_HUMAN             Reviewed;         163 AA.
AC   Q6ZSV7;
DE   RecName: Full=Putative uncharacterized protein FLJ45177;
//
ID   YF009_HUMAN             Reviewed;         218 AA.
AC   Q6ZS46;
DE   RecName: Full=Putative uncharacterized protein FLJ45840;
//
ID   YF013_HUMAN             Reviewed;         159 AA.
AC   Q6ZS52;
DE   RecName: Full=Putative uncharacterized protein FLJ45825;
//
ID   YF016_HUMAN             Reviewed;         340 AA.
AC   A6NL46;
DE   RecName: Full=Putative UPF0607 protein ENSP00000332738;
//
ID   YG001_HUMAN             Reviewed;          67 AA.
AC   Q9UHT4;
DE   RecName: Full=Putative uncharacterized protein PRO1854;
GN   ORFNames=PRO1854;
//
ID   YG006_HUMAN             Reviewed;         154 AA.
AC   Q8NBF4;
DE   RecName: Full=Putative uncharacterized protein FLJ33307;
//
ID   YG018_HUMAN             Reviewed;         150 AA.
AC   A4D1N5; Q8N7V8;
DE   RecName: Full=Putative uncharacterized protein FLJ40288;
//
ID   YG024_HUMAN             Reviewed;         215 AA.
AC   Q6ZRM9;
DE   RecName: Full=Putative uncharacterized protein FLJ46235;
//
ID   YG039_HUMAN             Reviewed;         141 AA.
AC   Q8N976;
DE   RecName: Full=Putative uncharacterized protein FLJ38264;
//
ID   YG041_HUMAN             Reviewed;          49 AA.
AC   Q9BZS9;
DE   RecName: Full=Putative uncharacterized protein PNAS-138;
GN   ORFNames=PNAS-138;
//
ID   YG045_HUMAN             Reviewed;         137 AA.
AC   Q8N814;
DE   RecName: Full=Putative uncharacterized protein FLJ40140;
//
ID   YG046_HUMAN             Reviewed;         133 AA.
AC   Q9HAA7;
DE   RecName: Full=Putative uncharacterized protein FLJ11871;
//
ID   YG027_HUMAN             Reviewed;         129 AA.
AC   Q75L30; B2R4X6;
DE   RecName: Full=Putative uncharacterized protein FLJ92257;
//
ID   YG055_HUMAN             Reviewed;          59 AA.
AC   A4D0T7; Q32Q38;
DE   RecName: Full=Putative transmembrane protein LINC00998;
DE   Flags: Precursor;
GN   Name=LINC00998;
//
ID   YG056_HUMAN             Reviewed;          90 AA.
AC   A4D0Y5;
DE   RecName: Full=Putative uncharacterized protein LOC154872;
//
ID   YH006_HUMAN             Reviewed;         208 AA.
AC   Q71RG6;
DE   RecName: Full=Putative chemokine-related protein FP248;
DE   AltName: Full=Protein N73;
DE   Flags: Precursor;
GN   ORFNames=FP248;
//
ID   YH009_HUMAN             Reviewed;         311 AA.
AC   A8MV72;
DE   RecName: Full=Putative UPF0607 protein ENSP00000382826;
//
ID   YH007_HUMAN             Reviewed;         452 AA.
AC   Q8N7P7;
DE   RecName: Full=Uncharacterized protein FLJ40521;
//
ID   YH010_HUMAN             Reviewed;         604 AA.
AC   A8MXQ7;
DE   RecName: Full=Putative IQ motif and ankyrin repeat domain-containing protein LOC642574;
//
ID   YI001_HUMAN             Reviewed;         140 AA.
AC   Q96NJ1;
DE   RecName: Full=Uncharacterized protein FLJ30774;
//
ID   YI012_HUMAN             Reviewed;          93 AA.
AC   Q9H379;
DE   RecName: Full=Putative uncharacterized protein PRO3102;
GN   ORFNames=PRO3102;
//
ID   YI004_HUMAN             Reviewed;         183 AA.
AC   Q6UXR6;
DE   RecName: Full=Putative uncharacterized protein UNQ6494/PRO21346;
DE   Flags: Precursor;
GN   ORFNames=UNQ6494/PRO21346;
//
ID   YI018_HUMAN             Reviewed;         153 AA.
AC   Q8NFD4;
DE   RecName: Full=Uncharacterized protein FLJ76381;
//
ID   YI023_HUMAN             Reviewed;         163 AA.
AC   Q6ZSN1;
DE   RecName: Full=Putative uncharacterized protein FLJ45355;
//
ID   YI035_HUMAN             Reviewed;         320 AA.
AC   Q8NH95;
DE   RecName: Full=Putative olfactory receptor ENSP00000348552;
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
//
ID   YI028_HUMAN             Reviewed;         347 AA.
AC   A8MVJ9;
DE   RecName: Full=Putative UPF0609 protein C4orf27-like;
//
ID   YI025_HUMAN             Reviewed;         231 AA.
AC   Q8N1Y9; A7E2V8;
DE   RecName: Full=Putative uncharacterized protein FLJ37218;
DE   Flags: Precursor;
//
ID   YI036_HUMAN             Reviewed;         369 AA.
AC   A8MXE2;
DE   RecName: Full=Putative UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase LOC402377;
DE            EC=2.4.1.-;
DR   GO; GO:0008378; F:galactosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
//
ID   YI024_HUMAN             Reviewed;         223 AA.
AC   Q5PR19;
DE   RecName: Full=Putative UPF0607 protein LOC392364;
//
ID   YI029_HUMAN             Reviewed;          79 AA.
AC   Q5VSD8;
DE   RecName: Full=Putative uncharacterized protein LOC401522;
//
ID   YIF1A_HUMAN             Reviewed;         293 AA.
AC   O95070; A6NM00; Q96G83; Q9BVD0;
DE   RecName: Full=Protein YIF1A;
DE   AltName: Full=54TMp;
DE   AltName: Full=YIP1-interacting factor homolog A;
GN   Name=YIF1A; Synonyms=54TM, HYIF1P, YIF1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   YIF1B_HUMAN             Reviewed;         314 AA.
AC   Q5BJH7; H7BXS8; Q5JPC2; Q8WY70; Q96C02; Q96IC4;
DE   RecName: Full=Protein YIF1B;
DE   AltName: Full=YIP1-interacting factor homolog B;
GN   Name=YIF1B; ORFNames=PP4519, UNQ3073/PRO9905;
//
ID   YIPF1_HUMAN             Reviewed;         306 AA.
AC   Q9Y548; B2RCM7; D3DQ40; Q9NWJ1;
DE   RecName: Full=Protein YIPF1;
DE   AltName: Full=YIP1 family member 1;
GN   Name=YIPF1;
//
ID   YIPF2_HUMAN             Reviewed;         316 AA.
AC   Q9BWQ6;
DE   RecName: Full=Protein YIPF2;
DE   AltName: Full=YIP1 family member 2;
GN   Name=YIPF2;
//
ID   YIPF3_HUMAN             Reviewed;         350 AA.
AC   Q9GZM5; Q5JTD2; Q6FI85; Q8NI57; Q9NWE3; Q9Y3U9;
DE   RecName: Full=Protein YIPF3;
DE   AltName: Full=Killer lineage protein 1;
DE   AltName: Full=Natural killer cell-specific antigen KLIP1;
DE   AltName: Full=YIP1 family member 3;
DE   Contains:
DE     RecName: Full=Protein YIPF3, 36 kDa form III;
GN   Name=YIPF3; Synonyms=C6orf109, KLIP1;
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
//
ID   YIPF4_HUMAN             Reviewed;         244 AA.
AC   Q9BSR8;
DE   RecName: Full=Protein YIPF4;
DE   AltName: Full=YIP1 family member 4;
GN   Name=YIPF4; ORFNames=Nbla11189;
//
ID   YIPF5_HUMAN             Reviewed;         257 AA.
AC   Q969M3; D3DQF5; Q4VSN6; Q53EX4; Q8NHE5; Q9H338; Q9H3U4;
DE   RecName: Full=Protein YIPF5;
DE   AltName: Full=Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5;
DE   AltName: Full=Smooth muscle cell-associated protein 5;
DE            Short=SMAP-5;
DE   AltName: Full=YIP1 family member 5;
DE   AltName: Full=YPT-interacting protein 1 A;
GN   Name=YIPF5; Synonyms=FINGER5, YIP1A;
GN   ORFNames=PP12723, SB140, UNQ3123/PRO10275;
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   YIPF6_HUMAN             Reviewed;         236 AA.
AC   Q96EC8; B4E1U7; G5E997; Q5JP08;
DE   RecName: Full=Protein YIPF6;
DE   AltName: Full=YIP1 family member 6;
GN   Name=YIPF6;
DR   GO; GO:0060576; P:intestinal epithelial cell development; IEA:Ensembl.
//
ID   YIPF7_HUMAN             Reviewed;         280 AA.
AC   Q8N8F6; Q3SY21; Q3SY22;
DE   RecName: Full=Protein YIPF7;
DE   AltName: Full=Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 9;
DE   AltName: Full=YIP1 family member 7;
GN   Name=YIPF7; Synonyms=FINGER9, YIP1B;
//
ID   YJ001_HUMAN             Reviewed;         126 AA.
AC   Q9H354;
DE   RecName: Full=Putative uncharacterized protein PRO1933;
GN   ORFNames=PRO1933;
//
ID   YJ004_HUMAN             Reviewed;         158 AA.
AC   Q8N377;
DE   RecName: Full=Putative uncharacterized protein LOC387726;
//
ID   YJ005_HUMAN             Reviewed;         355 AA.
AC   Q6ZSR9;
DE   RecName: Full=Uncharacterized protein FLJ45252;
//
ID   YJ009_HUMAN             Reviewed;          83 AA.
AC   Q9H374;
DE   RecName: Full=Uncharacterized protein PRO1102;
GN   ORFNames=PRO1102;
//
ID   YJ012_HUMAN             Reviewed;         341 AA.
AC   Q8N9G6;
DE   RecName: Full=Putative UPF0607 protein FLJ37424;
//
ID   YJ006_HUMAN             Reviewed;         163 AA.
AC   Q96MT0;
DE   RecName: Full=Putative uncharacterized protein FLJ31958;
//
ID   YJ013_HUMAN             Reviewed;         251 AA.
AC   Q6ZQT7;
DE   RecName: Full=Putative uncharacterized protein FLJ44672;
//
ID   YJ010_HUMAN             Reviewed;          83 AA.
AC   A6NMP4;
DE   RecName: Full=Uncharacterized PRO1102-like protein LOC100132418;
//
ID   YJ016_HUMAN             Reviewed;         187 AA.
AC   Q499Y3;
DE   RecName: Full=Putative uncharacterized protein C10orf88-like;
//
ID   YJ017_HUMAN             Reviewed;         215 AA.
AC   Q8NDZ9;
DE   RecName: Full=Putative uncharacterized protein LOC439951;
//
ID   YJ018_HUMAN             Reviewed;         139 AA.
AC   P0C879;
DE   RecName: Full=Putative uncharacterized protein FLJ43185;
//
ID   YJEN3_HUMAN             Reviewed;         299 AA.
AC   A6XGL0; A6XGK9; Q4G1C0;
DE   RecName: Full=YjeF N-terminal domain-containing protein 3;
DE            Short=YjeF_N3;
DE            Short=hYjeF_N3;
GN   Name=YJEFN3;
//
ID   YK016_HUMAN             Reviewed;         147 AA.
AC   Q9BRP9;
DE   RecName: Full=Putative uncharacterized protein MGC13053;
//
ID   YK006_HUMAN             Reviewed;         254 AA.
AC   Q3ZCU0; Q8N9C3;
DE   RecName: Full=Putative uncharacterized protein FLJ37770;
//
ID   YK019_HUMAN             Reviewed;         154 AA.
AC   Q7Z469; Q4G0P1; Q4G197;
DE   RecName: Full=Putative mitochondrial carrier protein LOC494141;
DR   GO; GO:0006810; P:transport; IEA:UniProtKB-KW.
//
ID   YK022_HUMAN             Reviewed;         165 AA.
AC   Q6ZVU0;
DE   RecName: Full=Putative uncharacterized protein FLJ42102;
//
ID   YK004_HUMAN             Reviewed;         145 AA.
AC   Q6ZVH6;
DE   RecName: Full=Putative uncharacterized protein FLJ42569;
//
ID   YK026_HUMAN             Reviewed;         147 AA.
AC   Q6AWC8; Q3KQW1; Q6ZW01;
DE   RecName: Full=Putative uncharacterized protein LOC100129027;
//
ID   YK031_HUMAN             Reviewed;         446 AA.
AC   Q3C1W6;
DE   RecName: Full=Tripartite motif-containing protein LOC642612;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   YK039_HUMAN             Reviewed;          43 AA.
AC   Q9UHU1;
DE   RecName: Full=Putative uncharacterized protein PRO1716;
GN   ORFNames=PRO1716;
//
ID   YK038_HUMAN             Reviewed;         196 AA.
AC   Q8IYB0;
DE   RecName: Full=Putative uncharacterized protein MGC39545;
//
ID   YK032_HUMAN             Reviewed;         123 AA.
AC   Q6ZTI0;
DE   RecName: Full=Putative uncharacterized protein FLJ44636;
//
ID   YK033_HUMAN             Reviewed;         167 AA.
AC   A1L4Q6; Q6ZW93;
DE   RecName: Full=Putative uncharacterized protein FLJ41423;
//
ID   YK042_HUMAN             Reviewed;          94 AA.
AC   A6NHS1;
DE   RecName: Full=Putative uncharacterized protein ENSP00000347057;
//
ID   YK041_HUMAN             Reviewed;         767 AA.
AC   Q3C1V9; A6NNX0;
DE   RecName: Full=Putative uncharacterized protein ENSP00000334305;
//
ID   YK045_HUMAN             Reviewed;          98 AA.
AC   Q8TAT8;
DE   RecName: Full=Putative uncharacterized protein LOC644613;
DE   Flags: Precursor;
//
ID   YKT6_HUMAN              Reviewed;         198 AA.
AC   O15498; Q53F01; Q6FGU9; Q6IB15;
DE   RecName: Full=Synaptobrevin homolog YKT6;
DE            EC=2.3.1.-;
DE   Flags: Precursor;
GN   Name=YKT6;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IDA:HGNC.
DR   GO; GO:0005484; F:SNAP receptor activity; IDA:HGNC.
DR   GO; GO:0000149; F:SNARE binding; IBA:RefGenome.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IDA:HGNC.
DR   GO; GO:0008152; P:metabolic process; IDA:GOC.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IDA:HGNC.
DR   GO; GO:0006904; P:vesicle docking involved in exocytosis; IDA:HGNC.
DR   GO; GO:0006906; P:vesicle fusion; IBA:RefGenome.
DR   GO; GO:0006903; P:vesicle targeting; IDA:HGNC.
//
ID   YL004_HUMAN             Reviewed;         168 AA.
AC   Q6ZRX8;
DE   RecName: Full=Putative uncharacterized protein FLJ45999;
//
ID   YL016_HUMAN             Reviewed;         171 AA.
AC   Q0VFX4;
DE   RecName: Full=Putative uncharacterized protein LOC100128554;
//
ID   YL014_HUMAN             Reviewed;         128 AA.
AC   Q6ZUT4;
DE   RecName: Full=Putative uncharacterized protein FLJ43343;
//
ID   YL023_HUMAN             Reviewed;         143 AA.
AC   Q6ZV60;
DE   RecName: Full=Putative uncharacterized protein encoded by LINC00173;
GN   Name=LINC00173; Synonyms=NCRNA00173;
//
ID   YL021_HUMAN             Reviewed;         305 AA.
AC   A6NCN8;
DE   RecName: Full=Uncharacterized protein ENSP00000372125;
//
ID   YLAT1_HUMAN             Reviewed;         511 AA.
AC   Q9UM01; B2RAU0; D3DS26; O95984; Q53XC1; Q86U07; Q9P2V5;
DE   RecName: Full=Y+L amino acid transporter 1;
DE   AltName: Full=Monocyte amino acid permease 2;
DE            Short=MOP-2;
DE   AltName: Full=Solute carrier family 7 member 7;
DE   AltName: Full=y(+)L-type amino acid transporter 1;
DE            Short=Y+LAT1;
DE            Short=y+LAT-1;
GN   Name=SLC7A7;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   YLAT2_HUMAN             Reviewed;         515 AA.
AC   Q92536; Q68DS4; Q7L1N3;
DE   RecName: Full=Y+L amino acid transporter 2;
DE   AltName: Full=Cationic amino acid transporter, y+ system;
DE   AltName: Full=Solute carrier family 7 member 6;
DE   AltName: Full=y(+)L-type amino acid transporter 2;
DE            Short=Y+LAT2;
DE            Short=y+LAT-2;
GN   Name=SLC7A6; Synonyms=KIAA0245;
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006865; P:amino acid transport; TAS:Reactome.
DR   GO; GO:0007596; P:blood coagulation; TAS:Reactome.
DR   GO; GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc.
DR   GO; GO:0006811; P:ion transport; TAS:Reactome.
DR   GO; GO:0050900; P:leukocyte migration; TAS:Reactome.
DR   GO; GO:0006461; P:protein complex assembly; TAS:ProtInc.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
//
ID   YLPM1_HUMAN             Reviewed;        1951 AA.
AC   P49750; P49752; Q96I64; Q9P1V7;
DE   RecName: Full=YLP motif-containing protein 1;
DE   AltName: Full=Nuclear protein ZAP3;
DE   AltName: Full=ZAP113;
GN   Name=YLPM1; Synonyms=C14orf170, ZAP3;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0032204; P:regulation of telomere maintenance; IEA:Ensembl.
//
ID   YM012_HUMAN             Reviewed;         564 AA.
AC   Q9UF83; Q9NTQ6; Q9UFS5;
DE   RecName: Full=Uncharacterized protein DKFZp434B061;
//
ID   YM006_HUMAN             Reviewed;          79 AA.
AC   Q9H521;
DE   RecName: Full=Putative uncharacterized protein LOC645739;
//
ID   YM017_HUMAN             Reviewed;         341 AA.
AC   A8MX80;
DE   RecName: Full=Putative UPF0607 protein ENSP00000383144;
//
ID   YMEL1_HUMAN             Reviewed;         773 AA.
AC   Q96TA2; B4DNM1; D3DRV8; D3DRV9; Q5T8D9; Q9H1Q0; Q9UMR9;
DE   RecName: Full=ATP-dependent zinc metalloprotease YME1L1;
DE            EC=3.4.24.-;
DE   AltName: Full=ATP-dependent metalloprotease FtsH1;
DE   AltName: Full=Meg-4;
DE   AltName: Full=Presenilin-associated metalloprotease;
DE            Short=PAMP;
DE   AltName: Full=YME1-like protein 1;
GN   Name=YME1L1; Synonyms=FTSH1, YME1L; ORFNames=UNQ1868/PRO4304;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR   GO; GO:0008283; P:cell proliferation; IMP:UniProtKB.
DR   GO; GO:0006515; P:misfolded or incompletely synthesized protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; IMP:UniProtKB.
//
ID   YN009_HUMAN             Reviewed;         194 AA.
AC   Q6ZR54;
DE   RecName: Full=Putative uncharacterized protein FLJ46641;
//
ID   YN011_HUMAN             Reviewed;         197 AA.
AC   A8MYG8;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein ENSP00000383069;
//
ID   YN010_HUMAN             Reviewed;          46 AA.
AC   Q9P1C3;
DE   RecName: Full=Putative uncharacterized protein PRO2829;
DE   Flags: Precursor;
GN   ORFNames=PRO2829;
//
ID   YO002_HUMAN             Reviewed;         127 AA.
AC   Q6UXQ8;
DE   RecName: Full=Putative uncharacterized protein UNQ6190/PRO20217;
DE   Flags: Precursor;
GN   ORFNames=UNQ6190/PRO20217;
//
ID   YO007_HUMAN             Reviewed;         132 AA.
AC   Q9UFV3;
DE   RecName: Full=Putative uncharacterized protein DKFZp434L187;
//
ID   YO001_HUMAN             Reviewed;         181 AA.
AC   Q6UXP9;
DE   RecName: Full=Putative uncharacterized protein UNQ9370/PRO34162;
GN   ORFNames=UNQ9370/PRO34162;
//
ID   YO011_HUMAN             Reviewed;         124 AA.
AC   A6NDX4;
DE   RecName: Full=Putative transmembrane protein ENSP00000320207;
//
ID   YO010_HUMAN             Reviewed;         124 AA.
AC   Q8N9W7;
DE   RecName: Full=Putative transmembrane protein FLJ36131;
//
ID   YO026_HUMAN             Reviewed;         126 AA.
AC   Q6ZQY7;
DE   RecName: Full=Putative uncharacterized protein FLJ46792;
//
ID   YO028_HUMAN             Reviewed;         132 AA.
AC   Q96MF0; B2RPC9;
DE   RecName: Full=Putative uncharacterized protein LOC100506887;
//
ID   YO027_HUMAN             Reviewed;         168 AA.
AC   Q6ZSR3;
DE   RecName: Full=Putative uncharacterized protein FLJ45275, mitochondrial;
DE   Flags: Precursor;
//
ID   YP007_HUMAN             Reviewed;         202 AA.
AC   Q6ZSR6; A2RU57;
DE   RecName: Full=Putative uncharacterized protein FLJ45256;
//
ID   YP008_HUMAN             Reviewed;          64 AA.
AC   Q9P1D8;
DE   RecName: Full=Putative uncharacterized protein PRO2289;
GN   ORFNames=PRO2289;
//
ID   YP009_HUMAN             Reviewed;         789 AA.
AC   Q6ZNL0; Q6ZNK9;
DE   RecName: Full=GPS, PLAT and transmembrane domain-containing protein FLJ00285;
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
//
ID   YP002_HUMAN             Reviewed;          63 AA.
AC   Q9UI25;
DE   RecName: Full=Putative uncharacterized protein PRO0461;
GN   ORFNames=PRO0461;
//
ID   YP010_HUMAN             Reviewed;         194 AA.
AC   Q96M66;
DE   RecName: Full=Putative uncharacterized protein FLJ32790;
//
ID   YP023_HUMAN             Reviewed;         132 AA.
AC   Q8NAQ8;
DE   RecName: Full=Putative uncharacterized protein FLJ34945;
//
ID   YP021_HUMAN             Reviewed;         173 AA.
AC   Q8N6K4; B2R6Y3;
DE   RecName: Full=Putative uncharacterized protein MGC34800;
//
ID   YP015_HUMAN             Reviewed;         550 AA.
AC   Q6ZTK2;
DE   RecName: Full=Putative uncharacterized protein LOC400499;
//
ID   YP034_HUMAN             Reviewed;         341 AA.
AC   A8MU76;
DE   RecName: Full=Putative UPF0607 protein ENSP00000381418;
//
ID   YP029_HUMAN             Reviewed;         208 AA.
AC   Q6ZRN7;
DE   RecName: Full=Putative uncharacterized protein FLJ46214;
//
ID   YP033_HUMAN             Reviewed;         140 AA.
AC   Q6ZVL8;
DE   RecName: Full=Putative uncharacterized protein FLJ42384;
//
ID   YPEL1_HUMAN             Reviewed;         119 AA.
AC   O60688; Q65ZA1; Q6GLI6;
DE   RecName: Full=Protein yippee-like 1;
GN   Name=YPEL1; ORFNames=FKSG3;
DR   GO; GO:0051898; P:negative regulation of protein kinase B signaling; IEA:Ensembl.
DR   GO; GO:0031641; P:regulation of myelination; IEA:Ensembl.
//
ID   YPEL2_HUMAN             Reviewed;         119 AA.
AC   Q96QA6; A0PK16; A2RUG4; Q65ZA0; Q8N3W2;
DE   RecName: Full=Protein yippee-like 2;
GN   Name=YPEL2; ORFNames=FKSG4;
//
ID   YPEL3_HUMAN             Reviewed;         119 AA.
AC   P61236; Q65Z99; Q86VK6; Q9BSJ4; Q9CQB6;
DE   RecName: Full=Protein yippee-like 3;
GN   Name=YPEL3; ORFNames=FKSG5;
//
ID   YPEL4_HUMAN             Reviewed;         127 AA.
AC   Q96NS1; B3KW92; Q2M3U7; Q65Z98;
DE   RecName: Full=Protein yippee-like 4;
GN   Name=YPEL4;
//
ID   YPEL5_HUMAN             Reviewed;         121 AA.
AC   P62699; D6W568; Q65Z97; Q8R174; Q9D6M1; Q9UMX7; Q9Y3C9;
DE   RecName: Full=Protein yippee-like 5;
GN   Name=YPEL5; ORFNames=CGI-127;
//
ID   YQ014_HUMAN             Reviewed;          97 AA.
AC   A6NIN4;
DE   RecName: Full=Putative uncharacterized protein FLJ38447;
//
ID   YQ018_HUMAN             Reviewed;         166 AA.
AC   A8MXK9; A8MTZ3; Q9H627;
DE   RecName: Full=Uncharacterized protein ENSP00000382033;
//
ID   YQ019_HUMAN             Reviewed;         167 AA.
AC   A8MWP6; A8MUB3; Q9H627;
DE   RecName: Full=Uncharacterized protein ENSP00000382042;
//
ID   YQ015_HUMAN             Reviewed;         221 AA.
AC   Q6ZRG5;
DE   RecName: Full=Putative uncharacterized protein FLJ43944;
//
ID   YQ032_HUMAN             Reviewed;         148 AA.
AC   Q6ZRU5; A6NG26;
DE   RecName: Full=Putative uncharacterized protein FLJ46089;
DE   Flags: Precursor;
//
ID   YQ041_HUMAN             Reviewed;          79 AA.
AC   A6NJY4;
DE   RecName: Full=Putative transmembrane protein LOC100289255;
//
ID   YQ037_HUMAN             Reviewed;         164 AA.
AC   A8MZ25;
DE   RecName: Full=Putative uncharacterized protein FLJ38767;
//
ID   YQ047_HUMAN             Reviewed;          97 AA.
AC   A8MU10;
DE   RecName: Full=Putative uncharacterized protein ENSP00000381562;
//
ID   YQ048_HUMAN             Reviewed;         132 AA.
AC   A8MUN3;
DE   RecName: Full=Putative uncharacterized protein ENSP00000381830;
DE   Flags: Precursor;
//
ID   YQ050_HUMAN             Reviewed;         121 AA.
AC   Q6ZS49;
DE   RecName: Full=Putative uncharacterized protein FLJ45831;
//
ID   YR005_HUMAN             Reviewed;         130 AA.
AC   Q6ZT83;
DE   RecName: Full=Uncharacterized protein FLJ44881;
//
ID   YR007_HUMAN             Reviewed;         248 AA.
AC   A8MQB9;
DE   RecName: Full=Putative ankyrin repeat domain-containing protein ENSP00000330211;
//
ID   YRDC_HUMAN              Reviewed;         279 AA.
AC   Q86U90; Q4W4X8; Q6NVW3; Q7L4E4; Q7Z2I4; Q9H5F8;
DE   RecName: Full=YrdC domain-containing protein, mitochondrial;
DE   AltName: Full=Dopamine receptor-interacting protein 3;
DE   AltName: Full=Ischemia/reperfusion-inducible protein homolog;
DE            Short=hIRIP;
DE   Flags: Precursor;
GN   Name=YRDC; Synonyms=DRIP3, IRIP;
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR   GO; GO:0051051; P:negative regulation of transport; IDA:MGI.
//
ID   YS002_HUMAN             Reviewed;         137 AA.
AC   Q6UXU0;
DE   RecName: Full=Putative uncharacterized protein UNQ9165/PRO28630;
DE   Flags: Precursor;
GN   ORFNames=UNQ9165/PRO28630;
//
ID   YS001_HUMAN             Reviewed;         122 AA.
AC   Q6UXR8;
DE   RecName: Full=Putative uncharacterized protein UNQ6493/PRO21345;
GN   ORFNames=UNQ6493/PRO21345;
//
ID   YS003_HUMAN             Reviewed;         219 AA.
AC   Q96FF7;
DE   RecName: Full=Uncharacterized protein LOC113230;
//
ID   YS006_HUMAN             Reviewed;         134 AA.
AC   Q8WZ26;
DE   RecName: Full=Putative uncharacterized protein PP6455;
GN   ORFNames=PP6455;
//
ID   YS014_HUMAN             Reviewed;         123 AA.
AC   Q8N3U1;
DE   RecName: Full=Putative uncharacterized protein LOC400692;
//
ID   YS027_HUMAN             Reviewed;         616 AA.
AC   Q9H6K5; Q9H3X1;
DE   RecName: Full=Putative uncharacterized protein FLJ22184;
//
ID   YS025_HUMAN             Reviewed;         131 AA.
AC   Q6ZSA8;
DE   RecName: Full=Putative uncharacterized protein FLJ45684;
//
ID   YS049_HUMAN             Reviewed;         238 AA.
AC   Q8WTZ3;
DE   RecName: Full=Zinc finger protein ENSP00000375192;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   YS060_HUMAN             Reviewed;         382 AA.
AC   I3L1I5;
DE   RecName: Full=Putative uncharacterized protein LOC100996504;
//
ID   YS039_HUMAN             Reviewed;         131 AA.
AC   Q6ZPA2;
DE   RecName: Full=Putative uncharacterized protein FLJ26174;
//
ID   YS045_HUMAN             Reviewed;         151 AA.
AC   Q6ZVQ6;
DE   RecName: Full=Putative uncharacterized protein FLJ42213;
//
ID   YS043_HUMAN             Reviewed;         215 AA.
AC   Q6ZWC4;
DE   RecName: Full=Putative uncharacterized protein LOC100128429;
//
ID   YT011_HUMAN             Reviewed;         140 AA.
AC   Q5W150;
DE   RecName: Full=Putative uncharacterized protein MGC163334;
//
ID   YT001_HUMAN             Reviewed;          55 AA.
AC   Q9UI54;
DE   RecName: Full=Putative uncharacterized protein PRO0628;
GN   ORFNames=PRO0628;
//
ID   YT009_HUMAN             Reviewed;         211 AA.
AC   Q6ZTC4;
DE   RecName: Full=Putative uncharacterized protein FLJ44790;
//
ID   YT014_HUMAN             Reviewed;         135 AA.
AC   P0C880;
DE   RecName: Full=Putative uncharacterized protein FLJ40606;
//
ID   YTDC1_HUMAN             Reviewed;         727 AA.
AC   Q96MU7; Q4W5Q3; Q7Z622; Q8TF35;
DE   RecName: Full=YTH domain-containing protein 1;
DE   AltName: Full=Putative splicing factor YT521;
DE            Short=YT521-B;
GN   Name=YTHDC1; Synonyms=KIAA1966, YT521;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IDA:UniProtKB.
DR   GO; GO:0006376; P:mRNA splice site selection; IDA:UniProtKB.
//
ID   YTDC2_HUMAN             Reviewed;        1430 AA.
AC   Q9H6S0; B2RP66;
DE   RecName: Full=Probable ATP-dependent RNA helicase YTHDC2;
DE            EC=3.6.4.13;
GN   Name=YTHDC2;
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   YTHD3_HUMAN             Reviewed;         585 AA.
AC   Q7Z739; B3KXL4; Q63Z37; Q659A3;
DE   RecName: Full=YTH domain-containing family protein 3;
GN   Name=YTHDF3;
DR   GO; GO:1990247; F:N6-methyladenosine-containing RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   YTHD2_HUMAN             Reviewed;         579 AA.
AC   Q9Y5A9; A6NKG4; A8K966; B4E1G7; D3DPM8; Q5VSZ9; Q8TDH0; Q9BUJ5;
DE   RecName: Full=YTH domain-containing family protein 2;
DE   AltName: Full=CLL-associated antigen KW-14;
DE   AltName: Full=High-glucose-regulated protein 8;
DE   AltName: Full=Renal carcinoma antigen NY-REN-2;
GN   Name=YTHDF2; Synonyms=HGRG8;
DR   GO; GO:1990247; F:N6-methyladenosine-containing RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006959; P:humoral immune response; TAS:ProtInc.
DR   GO; GO:0043488; P:regulation of mRNA stability; IMP:UniProtKB.
//
ID   YTHD1_HUMAN             Reviewed;         559 AA.
AC   Q9BYJ9; Q8N3G5; Q8TBT1; Q96AN4; Q96S57; Q9BTI7; Q9NX79;
DE   RecName: Full=YTH domain-containing family protein 1;
DE   AltName: Full=Dermatomyositis associated with cancer putative autoantigen 1;
DE            Short=DACA-1;
GN   Name=YTHDF1; Synonyms=C20orf21;
DR   GO; GO:1990247; F:N6-methyladenosine-containing RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   YU004_HUMAN             Reviewed;         302 AA.
AC   Q6ZR03; Q2T9F2;
DE   RecName: Full=Uncharacterized protein FLJ46757;
//
ID   YU005_HUMAN             Reviewed;         165 AA.
AC   A8MT66;
DE   RecName: Full=Putative uncharacterized protein ENSP00000383407;
//
ID   YU008_HUMAN             Reviewed;         228 AA.
AC   A8MWP4;
DE   RecName: Full=Putative uncharacterized protein ENSP00000401716;
//
ID   YU007_HUMAN             Reviewed;         139 AA.
AC   A8MWV9;
DE   RecName: Full=Putative uncharacterized protein LOC388820;
//
ID   YV006_HUMAN             Reviewed;         120 AA.
AC   Q8N9L7;
DE   RecName: Full=Putative uncharacterized protein FLJ36925;
//
ID   YV008_HUMAN             Reviewed;         177 AA.
AC   Q96M85;
DE   RecName: Full=Putative uncharacterized protein FLJ32756;
//
ID   YV010_HUMAN             Reviewed;         157 AA.
AC   Q6UXV3;
DE   RecName: Full=Uncharacterized protein UNQ6126/PRO20091;
DE   Flags: Precursor;
GN   ORFNames=UNQ6126/PRO20091;
//
ID   YV004_HUMAN             Reviewed;         128 AA.
AC   Q8TCH9;
DE   RecName: Full=Putative uncharacterized protein FLJ23865;
//
ID   YV012_HUMAN             Reviewed;         391 AA.
AC   Q6ZQY2;
DE   RecName: Full=Leucine-rich repeat-containing protein LOC400891;
//
ID   YV007_HUMAN             Reviewed;          41 AA.
AC   Q96IR3;
DE   RecName: Full=Putative uncharacterized protein MGC15705;
//
ID   YV020_HUMAN             Reviewed;         240 AA.
AC   Q8N402;
DE   RecName: Full=Putative uncharacterized protein LOC388882;
//
ID   YV018_HUMAN             Reviewed;         102 AA.
AC   Q5BKY6;
DE   RecName: Full=Putative uncharacterized protein DKFZp434K191;
//
ID   YV023_HUMAN             Reviewed;         505 AA.
AC   A8MUU9;
DE   RecName: Full=Putative uncharacterized protein ENSP00000383309;
//
ID   YX004_HUMAN             Reviewed;         123 AA.
AC   Q8N8P6;
DE   RecName: Full=Putative uncharacterized protein FLJ39060;
//
ID   YX002_HUMAN             Reviewed;          45 AA.
AC   Q9BTK2;
DE   RecName: Full=Putative uncharacterized protein LOC642776;
//
ID   YYAP1_HUMAN             Reviewed;         796 AA.
AC   Q9H869; B0QZ54; B4DMP2; B4E0I0; D3DV96; D3DV98; H7BY62; Q5VYZ1;
AC   Q5VYZ4; Q5VYZ7; Q7L4C3; Q7L5E2; Q8IXA6; Q8TEW5; Q8TF04; Q96HB6;
AC   Q9BQ64; Q9NV84;
DE   RecName: Full=YY1-associated protein 1;
DE   AltName: Full=Hepatocellular carcinoma susceptibility protein;
DE   AltName: Full=Hepatocellular carcinoma-associated protein 2;
GN   Name=YY1AP1; Synonyms=HCCA2, YY1AP;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   YYY4_HUMAN              Reviewed;          68 AA.
AC   Q9UI56;
DE   RecName: Full=Very putative protein from MEG3 locus;
GN   Name=MEG3; ORFNames=PRO0518;
DR   GO; GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0007411; P:axon guidance; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; ISS:UniProtKB.
DR   GO; GO:0032274; P:gonadotropin secretion; IMP:UniProtKB.
DR   GO; GO:0044029; P:hypomethylation of CpG island; ISS:UniProtKB.
DR   GO; GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:2000279; P:negative regulation of DNA biosynthetic process; IDA:UniProtKB.
DR   GO; GO:0045746; P:negative regulation of Notch signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0040019; P:positive regulation of embryonic development; ISS:UniProtKB.
DR   GO; GO:0048743; P:positive regulation of skeletal muscle fiber development; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0034337; P:RNA folding; IDA:UniProtKB.
//
ID   Z280A_HUMAN             Reviewed;         542 AA.
AC   P59817;
DE   RecName: Full=Zinc finger protein 280A;
DE   AltName: Full=3'OY11.1;
DE   AltName: Full=Suppressor of hairy wing homolog 1;
DE   AltName: Full=Zinc finger protein 636;
GN   Name=ZNF280A; Synonyms=SUHW1, ZNF280, ZNF636;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z280D_HUMAN             Reviewed;         979 AA.
AC   Q6N043; A1L495; B2RMT6; Q6MZM6; Q6N085; Q6P2R6; Q7Z6J5; Q9H0U5;
AC   Q9HCI8; Q9NXS0;
DE   RecName: Full=Zinc finger protein 280D;
DE   AltName: Full=Suppressor of hairy wing homolog 4;
DE   AltName: Full=Zinc finger protein 634;
GN   Name=ZNF280D; Synonyms=KIAA1584, SUHW4, ZNF634;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z280B_HUMAN             Reviewed;         543 AA.
AC   Q86YH2;
DE   RecName: Full=Zinc finger protein 280B;
DE   AltName: Full=5'OY11.1;
DE   AltName: Full=Suppressor of hairy wing homolog 2;
DE   AltName: Full=Zinc finger protein 279;
DE   AltName: Full=Zinc finger protein 632;
GN   Name=ZNF280B; Synonyms=SUHW2, ZNF279, ZNF632;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z280C_HUMAN             Reviewed;         737 AA.
AC   Q8ND82; A8K2V8; Q9NXR3;
DE   RecName: Full=Zinc finger protein 280C;
DE   AltName: Full=Suppressor of hairy wing homolog 3;
DE   AltName: Full=Zinc finger protein 633;
GN   Name=ZNF280C; Synonyms=SUHW3, ZNF633;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z286A_HUMAN             Reviewed;         521 AA.
AC   Q9HBT8; Q96JF3;
DE   RecName: Full=Zinc finger protein 286A;
GN   Name=ZNF286A; Synonyms=KIAA1874, ZNF286;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z286B_HUMAN             Reviewed;         522 AA.
AC   P0CG31;
DE   RecName: Full=Putative zinc finger protein 286B;
GN   Name=ZNF286B; Synonyms=ZNF286C, ZNF286L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z324A_HUMAN             Reviewed;         553 AA.
AC   O75467; B3KRX1;
DE   RecName: Full=Zinc finger protein 324A;
DE   AltName: Full=Zinc finger protein ZF5128;
GN   Name=ZNF324; Synonyms=ZNF324A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z324B_HUMAN             Reviewed;         544 AA.
AC   Q6AW86; B2RTZ6; Q6ZMX8; Q6ZS42;
DE   RecName: Full=Zinc finger protein 324B;
GN   Name=ZNF324B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z354A_HUMAN             Reviewed;         605 AA.
AC   O60765; Q9UNJ8;
DE   RecName: Full=Zinc finger protein 354A;
DE   AltName: Full=Transcription factor 17;
DE            Short=TCF-17;
DE   AltName: Full=Zinc finger protein eZNF;
GN   Name=ZNF354A; Synonyms=EZNF, HKL1, TCF17;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007576; P:nucleolar fragmentation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0051593; P:response to folic acid; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0007605; P:sensory perception of sound; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z354B_HUMAN             Reviewed;         612 AA.
AC   Q96LW1; A8K0V2; Q5U5Z4;
DE   RecName: Full=Zinc finger protein 354B;
GN   Name=ZNF354B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z354C_HUMAN             Reviewed;         554 AA.
AC   Q86Y25; Q6P4P9; Q8NFX1;
DE   RecName: Full=Zinc finger protein 354C;
DE   AltName: Full=Kidney, ischemia, and developmentally-regulated protein 3;
DE            Short=hKID3;
GN   Name=ZNF354C; Synonyms=KID3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z355P_HUMAN             Reviewed;         428 AA.
AC   Q9NSJ1;
DE   RecName: Full=Putative zinc finger protein 355P;
DE   AltName: Full=Zinc finger protein ZnFP01;
GN   Name=ZNF355P; Synonyms=ZNF834; ORFNames=PRED65;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z385A_HUMAN             Reviewed;         386 AA.
AC   Q96PM9; B2RDN5; B4DKH2; F1T0F1; J3KNS3; Q5VH53; Q9H7R6; Q9UFU3;
DE   RecName: Full=Zinc finger protein 385A;
DE   AltName: Full=Hematopoietic zinc finger protein;
DE   AltName: Full=Retinal zinc finger protein;
GN   Name=ZNF385A; Synonyms=HZF, RZF, ZNF385;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; ISS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; ISS:UniProtKB.
DR   GO; GO:0007599; P:hemostasis; IEA:Ensembl.
DR   GO; GO:0007611; P:learning or memory; IEA:Ensembl.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; ISS:UniProtKB.
DR   GO; GO:0010609; P:mRNA localization resulting in posttranscriptional regulation of gene expression; ISS:UniProtKB.
DR   GO; GO:1902166; P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IMP:UniProtKB.
DR   GO; GO:0070889; P:platelet alpha granule organization; IEA:Ensembl.
DR   GO; GO:0030220; P:platelet formation; IEA:Ensembl.
DR   GO; GO:1902164; P:positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000765; P:regulation of cytoplasmic translation; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z385B_HUMAN             Reviewed;         471 AA.
AC   Q569K4; Q49A04; Q6ZMZ7; Q8IY01; Q8N8H2; Q96DK4;
DE   RecName: Full=Zinc finger protein 385B;
DE   AltName: Full=Zinc finger protein 533;
GN   Name=ZNF385B; Synonyms=ZNF533;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IDA:UniProtKB.
//
ID   Z385C_HUMAN             Reviewed;         422 AA.
AC   Q66K41; Q4G0J1;
DE   RecName: Full=Zinc finger protein 385C;
GN   Name=ZNF385C;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   Z385D_HUMAN             Reviewed;         395 AA.
AC   Q9H6B1;
DE   RecName: Full=Zinc finger protein 385D;
DE   AltName: Full=Zinc finger protein 659;
GN   Name=ZNF385D; Synonyms=ZNF659;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   Z3H7A_HUMAN             Reviewed;         971 AA.
AC   Q8IWR0; D3DUG5; Q9NPE9;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 7A;
GN   Name=ZC3H7A; Synonyms=ZC3H7, ZC3HDC7; ORFNames=HSPC055;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   Z3H7B_HUMAN             Reviewed;         993 AA.
AC   Q9UGR2; A7YY88; B2RCA4; Q5TFX9; Q8TBT9; Q9H8B6; Q9UGQ9; Q9UGR0;
AC   Q9UGR1; Q9UK03; Q9UPW9;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 7B;
DE   AltName: Full=Rotavirus 'X'-associated non-structural protein;
DE            Short=RoXaN;
GN   Name=ZC3H7B; Synonyms=KIAA1031;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   Z512B_HUMAN             Reviewed;         892 AA.
AC   Q96KM6; Q08AK9; Q9ULM4;
DE   RecName: Full=Zinc finger protein 512B;
GN   Name=ZNF512B; Synonyms=KIAA1196;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z518A_HUMAN             Reviewed;        1483 AA.
AC   Q6AHZ1; A0PJI5; O15044; Q32MP4;
DE   RecName: Full=Zinc finger protein 518A;
GN   Name=ZNF518A; Synonyms=KIAA0335, ZNF518;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z518B_HUMAN             Reviewed;        1074 AA.
AC   Q9C0D4; Q96LN8;
DE   RecName: Full=Zinc finger protein 518B;
GN   Name=ZNF518B; Synonyms=KIAA1729;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   Z585A_HUMAN             Reviewed;         769 AA.
AC   Q6P3V2; Q8TE95; Q96MV3;
DE   RecName: Full=Zinc finger protein 585A;
GN   Name=ZNF585A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z585B_HUMAN             Reviewed;         769 AA.
AC   Q52M93; Q8IZD3; Q96JW6;
DE   RecName: Full=Zinc finger protein 585B;
DE   AltName: Full=zinc finger protein 41-like protein;
GN   Name=ZNF585B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z587B_HUMAN             Reviewed;         402 AA.
AC   E7ETH6; B4DR41;
DE   RecName: Full=Zinc finger protein 587B;
GN   Name=ZNF587B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   Z658B_HUMAN             Reviewed;         819 AA.
AC   Q4V348; Q8N946;
DE   RecName: Full=Zinc finger protein 658B;
GN   Name=ZNF658B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z705A_HUMAN             Reviewed;         300 AA.
AC   Q6ZN79;
DE   RecName: Full=Zinc finger protein 705A;
GN   Name=ZNF705A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z705B_HUMAN             Reviewed;         300 AA.
AC   P0CI00; A8K971; A8MY01;
DE   RecName: Full=Putative zinc finger protein 705B;
GN   Name=ZNF705B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z705D_HUMAN             Reviewed;         300 AA.
AC   P0CH99; A8K971; A8MY01; Q2TAN0;
DE   RecName: Full=Zinc finger protein 705D;
GN   Name=ZNF705D;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z705E_HUMAN             Reviewed;         302 AA.
AC   A8MWA4;
DE   RecName: Full=Putative zinc finger protein 705E;
GN   Name=ZNF705E;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z705F_HUMAN             Reviewed;         300 AA.
AC   A8MVS1;
DE   RecName: Full=Zinc finger protein 705F;
GN   Name=ZNF705F;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z780B_HUMAN             Reviewed;         833 AA.
AC   Q9Y6R6; B9EH00;
DE   RecName: Full=Zinc finger protein 780B;
DE   AltName: Full=Zinc finger protein 779;
GN   Name=ZNF780B; Synonyms=ZNF779;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z780A_HUMAN             Reviewed;         641 AA.
AC   O75290; E9PB48; Q6ZN87;
DE   RecName: Full=Zinc finger protein 780A;
GN   Name=ZNF780A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z705G_HUMAN             Reviewed;         300 AA.
AC   A8MUZ8;
DE   RecName: Full=Putative zinc finger protein 705G;
GN   Name=ZNF705G;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   Z804A_HUMAN             Reviewed;        1209 AA.
AC   Q7Z570; A7E253; Q6ZN26;
DE   RecName: Full=Zinc finger protein 804A;
GN   Name=ZNF804A; Synonyms=C2orf10;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   Z804B_HUMAN             Reviewed;        1349 AA.
AC   A4D1E1; B2RTV2; Q7Z714; Q96MN7;
DE   RecName: Full=Zinc finger protein 804B;
GN   Name=ZNF804B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   Z876P_HUMAN             Reviewed;         203 AA.
AC   Q49A33;
DE   RecName: Full=Putative zinc finger protein 876;
GN   Name=ZNF876P;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZA2G_HUMAN              Reviewed;         298 AA.
AC   P25311; D6W5T8; O60386; Q5XKQ4; Q8N4N0;
DE   RecName: Full=Zinc-alpha-2-glycoprotein;
DE            Short=Zn-alpha-2-GP;
DE            Short=Zn-alpha-2-glycoprotein;
DE   Flags: Precursor;
GN   Name=AZGP1; Synonyms=ZAG, ZNGP1;
DR   GO; GO:0003823; F:antigen binding; IBA:RefGenome.
DR   GO; GO:0001948; F:glycoprotein binding; IPI:UniProt.
DR   GO; GO:0042605; F:peptide antigen binding; IEA:InterPro.
DR   GO; GO:0008320; F:protein transmembrane transporter activity; NAS:UniProtKB.
DR   GO; GO:0004540; F:ribonuclease activity; NAS:UniProtKB.
DR   GO; GO:0019882; P:antigen processing and presentation; IBA:RefGenome.
DR   GO; GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IDA:UniProtKB.
DR   GO; GO:0001580; P:detection of chemical stimulus involved in sensory perception of bitter taste; IDA:UniProt.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.
DR   GO; GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IEA:InterPro.
DR   GO; GO:0071806; P:protein transmembrane transport; NAS:GOC.
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
DR   GO; GO:0090501; P:RNA phosphodiester bond hydrolysis; NAS:GOC.
//
ID   ZACN_HUMAN              Reviewed;         412 AA.
AC   Q401N2; Q2TB29; Q6ZWK3; Q86YW4;
DE   RecName: Full=Zinc-activated ligand-gated ion channel;
DE   AltName: Full=Ligand-gated ion channel zinc-activated 1;
DE   AltName: Full=Ligand-gated ion-channel receptor L2;
DE   Flags: Precursor;
GN   Name=ZACN; Synonyms=L2, LGICZ, LGICZ1, ZAC;
DR   GuidetoPHARMACOLOGY; 587; -.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IC:HGNC.
DR   GO; GO:0010043; P:response to zinc ion; IDA:HGNC.
//
ID   ZADH2_HUMAN             Reviewed;         377 AA.
AC   Q8N4Q0; A8KA15;
DE   RecName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein 2;
DE            EC=1.-.-.-;
GN   Name=ZADH2;
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZAN_HUMAN               Reviewed;        2812 AA.
AC   Q9Y493; A0FKC8; D6W5W4; O00218; Q96L85; Q96L86; Q96L87; Q96L88;
AC   Q96L89; Q96L90; Q9BXN9; Q9BZ83; Q9BZ84; Q9BZ85; Q9BZ86; Q9BZ87;
AC   Q9BZ88;
DE   RecName: Full=Zonadhesin;
DE   Flags: Precursor;
GN   Name=ZAN;
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; NAS:UniProtKB.
DR   GO; GO:0016337; P:single organismal cell-cell adhesion; NAS:UniProtKB.
//
ID   ZAP70_HUMAN             Reviewed;         619 AA.
AC   P43403; A6NFP4; Q6PIA4; Q8IXD6; Q9UBS6;
DE   RecName: Full=Tyrosine-protein kinase ZAP-70;
DE            EC=2.7.10.2;
DE   AltName: Full=70 kDa zeta-chain associated protein;
DE   AltName: Full=Syk-related tyrosine kinase;
GN   Name=ZAP70; Synonyms=SRK;
DR   GuidetoPHARMACOLOGY; 2285; -.
DR   GO; GO:0005524; F:ATP binding; NAS:UniProtKB.
DR   GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB.
DR   GO; GO:0002250; P:adaptive immune response; TAS:UniProtKB.
DR   GO; GO:0042113; P:B cell activation; TAS:UniProtKB.
DR   GO; GO:0043366; P:beta selection; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; IDA:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
DR   GO; GO:0045060; P:negative thymic T cell selection; IEA:Ensembl.
DR   GO; GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
DR   GO; GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IEA:Ensembl.
DR   GO; GO:0046641; P:positive regulation of alpha-beta T cell proliferation; IEA:Ensembl.
DR   GO; GO:0050850; P:positive regulation of calcium-mediated signaling; IEA:Ensembl.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; IDA:MGI.
DR   GO; GO:0045059; P:positive thymic T cell selection; IDA:MGI.
DR   GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
DR   GO; GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0042110; P:T cell activation; TAS:UniProtKB.
DR   GO; GO:0070489; P:T cell aggregation; TAS:UniProtKB.
DR   GO; GO:0030217; P:T cell differentiation; NAS:UniProtKB.
DR   GO; GO:0072678; P:T cell migration; TAS:UniProtKB.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; TAS:UniProtKB.
//
ID   ZAR1_HUMAN              Reviewed;         424 AA.
AC   Q86SH2;
DE   RecName: Full=Zygote arrest protein 1;
DE   AltName: Full=Oocyte-specific maternal effect factor;
GN   Name=ZAR1;
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   ZAR1L_HUMAN             Reviewed;         321 AA.
AC   A6NP61; B2RV03; B7ZBU2;
DE   RecName: Full=ZAR1-like protein;
GN   Name=ZAR1L;
//
ID   ZB6CL_HUMAN             Reviewed;         236 AA.
AC   Q96FA7;
DE   RecName: Full=ZBED6 C-terminal-like protein;
GN   Name=ZBED6CL; Synonyms=C7orf29;
//
ID   ZBBX_HUMAN              Reviewed;         800 AA.
AC   A8MT70; A8MV69; B3KSC1; B5MDJ6; F2Z370; Q9H5T8;
DE   RecName: Full=Zinc finger B-box domain-containing protein 1;
GN   Name=ZBBX;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZBED1_HUMAN             Reviewed;         694 AA.
AC   O96006; Q96BY4;
DE   RecName: Full=Zinc finger BED domain-containing protein 1;
DE   AltName: Full=Putative Ac-like transposable element;
DE   AltName: Full=dREF homolog;
GN   Name=ZBED1; Synonyms=ALTE, DREF, KIAA0785, TRAMP;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; TAS:ProtInc.
DR   GO; GO:0008152; P:metabolic process; TAS:GOC.
//
ID   ZBED2_HUMAN             Reviewed;         218 AA.
AC   Q9BTP6; D3DN62;
DE   RecName: Full=Zinc finger BED domain-containing protein 2;
GN   Name=ZBED2;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZBED3_HUMAN             Reviewed;         234 AA.
AC   Q96IU2;
DE   RecName: Full=Zinc finger BED domain-containing protein 3;
DE   AltName: Full=Axin-interacting protein;
GN   Name=ZBED3;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.
DR   GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; ISS:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   ZBED4_HUMAN             Reviewed;        1171 AA.
AC   O75132; B2RZH1; Q1ECU0; Q9UGG8;
DE   RecName: Full=Zinc finger BED domain-containing protein 4;
GN   Name=ZBED4; Synonyms=KIAA0637;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZBED5_HUMAN             Reviewed;         693 AA.
AC   Q49AG3; B2RCC1; Q05D82; Q86WW3; Q9NT24; Q9UBJ4;
DE   RecName: Full=Zinc finger BED domain-containing protein 5;
DE   AltName: Full=Transposon-derived Buster1 transposase-like protein;
GN   Name=ZBED5; Synonyms=Buster1;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZBED6_HUMAN             Reviewed;         979 AA.
AC   P86452;
DE   RecName: Full=Zinc finger BED domain-containing protein 6;
GN   Name=ZBED6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBED8_HUMAN             Reviewed;         594 AA.
AC   Q8IZ13; D3DQJ9; Q9H5S8; Q9UH87;
DE   RecName: Full=Protein ZBED8;
DE   AltName: Full=Transposon-derived Buster3 transposase-like protein;
DE   AltName: Full=Zinc finger BED domain-containing protein 8;
GN   Name=ZBED8; Synonyms=Buster3, C5orf54;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZBP1_HUMAN              Reviewed;         429 AA.
AC   Q9H171; A2A2F7; B3KVA1; F5GYT1; Q5JY39; Q9BYW4;
DE   RecName: Full=Z-DNA-binding protein 1;
DE   AltName: Full=Tumor stroma and activated macrophage protein DLM-1;
GN   Name=ZBP1; Synonyms=C20orf183, DLM1;
DR   GO; GO:0003677; F:DNA binding; IDA:MGI.
DR   GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IEA:InterPro.
DR   GO; GO:0003692; F:left-handed Z-DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; TAS:Reactome.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.
DR   GO; GO:0060340; P:positive regulation of type I interferon-mediated signaling pathway; IEA:Ensembl.
//
ID   ZBT10_HUMAN             Reviewed;         871 AA.
AC   Q96DT7; A4FVD0; Q86W96; Q8IXI9; Q96MH9;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 10;
DE   AltName: Full=Zinc finger protein RIN ZF;
GN   Name=ZBTB10; Synonyms=RINZF, RINZFC;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT11_HUMAN             Reviewed;        1053 AA.
AC   O95625; Q2NKP9;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 11;
GN   Name=ZBTB11;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT12_HUMAN             Reviewed;         459 AA.
AC   Q9Y330; B0UY00; Q5JQ98;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 12;
DE   AltName: Full=Protein G10;
GN   Name=ZBTB12; Synonyms=C6orf46, G10, NG35;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT14_HUMAN             Reviewed;         449 AA.
AC   O43829; O00403; Q2TB80;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 14;
DE   AltName: Full=Zinc finger protein 161 homolog;
DE            Short=Zfp-161;
DE   AltName: Full=Zinc finger protein 478;
DE   AltName: Full=Zinc finger protein 5 homolog;
DE            Short=ZF5;
DE            Short=Zfp-5;
DE            Short=hZF5;
GN   Name=ZBTB14; Synonyms=ZFP161, ZNF478;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT16_HUMAN             Reviewed;         673 AA.
AC   Q05516; Q8TAL4;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 16;
DE   AltName: Full=Promyelocytic leukemia zinc finger protein;
DE   AltName: Full=Zinc finger protein 145;
DE   AltName: Full=Zinc finger protein PLZF;
GN   Name=ZBTB16; Synonyms=PLZF, ZNF145;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0006915; P:apoptotic process; NAS:UniProtKB.
DR   GO; GO:0051216; P:cartilage development; IDA:UniProtKB.
DR   GO; GO:0007417; P:central nervous system development; ISS:UniProtKB.
DR   GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR   GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0035136; P:forelimb morphogenesis; IEA:Ensembl.
DR   GO; GO:0030097; P:hemopoiesis; IDA:UniProtKB.
DR   GO; GO:0048133; P:male germ-line stem cell division; IEA:Ensembl.
DR   GO; GO:0001823; P:mesonephros development; ISS:UniProtKB.
DR   GO; GO:0030099; P:myeloid cell differentiation; TAS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0061036; P:positive regulation of cartilage development; IDA:UniProtKB.
DR   GO; GO:0032332; P:positive regulation of chondrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.
DR   GO; GO:0045778; P:positive regulation of ossification; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT17_HUMAN             Reviewed;         803 AA.
AC   Q13105; A0AV07; B4DXB4; B7ZLQ9; F5H411; Q15932; Q5JYB2; Q9NUC9;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 17;
DE   AltName: Full=Myc-interacting zinc finger protein 1;
DE            Short=Miz-1;
DE   AltName: Full=Zinc finger protein 151;
DE   AltName: Full=Zinc finger protein 60;
GN   Name=ZBTB17; Synonyms=MIZ1, ZNF151, ZNF60;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0007398; P:ectoderm development; IEA:Ensembl.
DR   GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:Reactome.
DR   GO; GO:0001702; P:gastrulation with mouth forming second; IEA:Ensembl.
DR   GO; GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT18_HUMAN             Reviewed;         522 AA.
AC   Q99592; A8K5U3; Q13397; Q5VU40; Q8N463; Q9UD99;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 18;
DE   AltName: Full=58 kDa repressor protein;
DE   AltName: Full=Transcriptional repressor RP58;
DE   AltName: Full=Translin-associated zinc finger protein 1;
DE            Short=TAZ-1;
DE   AltName: Full=Zinc finger protein 238;
DE   AltName: Full=Zinc finger protein C2H2-171;
GN   Name=ZBTB18; Synonyms=RP58, TAZ1, ZNF238;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR   GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0048666; P:neuron development; IEA:Ensembl.
DR   GO; GO:0051302; P:regulation of cell division; IEA:Ensembl.
DR   GO; GO:0007519; P:skeletal muscle tissue development; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT20_HUMAN             Reviewed;         741 AA.
AC   Q9HC78; Q63HP6; Q8N6R5; Q9Y410;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 20;
DE   AltName: Full=Dendritic-derived BTB/POZ zinc finger protein;
DE   AltName: Full=Zinc finger protein 288;
GN   Name=ZBTB20; Synonyms=DPZF, ZNF288;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
//
ID   ZBT21_HUMAN             Reviewed;        1066 AA.
AC   Q9ULJ3; Q5R2W1; Q5R2W2; Q6P4R0;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 21;
DE   AltName: Full=Zinc finger protein 295;
GN   Name=ZBTB21; Synonyms=KIAA1227, ZNF295;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT24_HUMAN             Reviewed;         697 AA.
AC   O43167; Q17RC6; Q5TED5; Q8N455;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 24;
DE   AltName: Full=Zinc finger protein 450;
GN   Name=ZBTB24; Synonyms=KIAA0441, ZNF450;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT22_HUMAN             Reviewed;         634 AA.
AC   O15209; B0V007; Q5HYV4; Q5STL0; Q5STR7; Q8WV82;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 22;
DE   AltName: Full=Protein BING1;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 22A;
DE   AltName: Full=Zinc finger protein 297;
GN   Name=ZBTB22; Synonyms=BING1, ZBTB22A, ZNF297;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT25_HUMAN             Reviewed;         435 AA.
AC   P24278; B3KUX6; Q8IYH9;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 25;
DE   AltName: Full=Zinc finger protein 46;
DE   AltName: Full=Zinc finger protein KUP;
GN   Name=ZBTB25; Synonyms=C14orf51, KUP, ZNF46;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0010467; P:gene expression; IEP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT26_HUMAN             Reviewed;         441 AA.
AC   Q9HCK0; B3KQ53; Q8WTR1;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 26;
DE   AltName: Full=Zinc finger protein 481;
DE   AltName: Full=Zinc finger protein Bioref;
GN   Name=ZBTB26; Synonyms=KIAA1572, ZNF481;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT32_HUMAN             Reviewed;         487 AA.
AC   Q9Y2Y4; Q8WVP2;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 32;
DE   AltName: Full=FANCC-interacting protein;
DE   AltName: Full=Fanconi anemia zinc finger protein;
DE   AltName: Full=Testis zinc finger protein;
DE   AltName: Full=Zinc finger protein 538;
GN   Name=ZBTB32; Synonyms=FAZF, TZFP, ZNF538;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0006281; P:DNA repair; TAS:Reactome.
DR   GO; GO:0030097; P:hemopoiesis; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0001817; P:regulation of cytokine production; IEA:Ensembl.
DR   GO; GO:0042098; P:T cell proliferation; IEA:Ensembl.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZBT34_HUMAN             Reviewed;         500 AA.
AC   Q8NCN2; Q38IA7; Q5VYE9;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 34;
GN   Name=ZBTB34; Synonyms=KIAA1993;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT37_HUMAN             Reviewed;         503 AA.
AC   Q5TC79; Q5TC80; Q96M87; Q9BQ88;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 37;
GN   Name=ZBTB37;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT38_HUMAN             Reviewed;        1195 AA.
AC   Q8NAP3; D3DNF6;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 38;
GN   Name=ZBTB38;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProt.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT40_HUMAN             Reviewed;        1239 AA.
AC   Q9NUA8; O75066; Q5TFU5; Q8N1R1;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 40;
GN   Name=ZBTB40; Synonyms=KIAA0478;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030282; P:bone mineralization; NAS:UniProtKB.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT39_HUMAN             Reviewed;         712 AA.
AC   O15060; A7MD38; Q9UD98;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 39;
GN   Name=ZBTB39; Synonyms=KIAA0352;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT41_HUMAN             Reviewed;         909 AA.
AC   Q5SVQ8; A2RUA8; Q6MZT8; Q6ZR25; Q7Z4T1; Q8IZ99;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 41;
GN   Name=ZBTB41; Synonyms=FRBZ1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT42_HUMAN             Reviewed;         422 AA.
AC   B2RXF5; B7ZW21;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 42;
GN   Name=ZBTB42;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT43_HUMAN             Reviewed;         467 AA.
AC   O43298; Q5JU96;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 43;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 22B;
DE   AltName: Full=Zinc finger protein 297B;
DE   AltName: Full=ZnF-x;
GN   Name=ZBTB43; Synonyms=KIAA0414, ZBTB22B, ZNF297B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT44_HUMAN             Reviewed;         570 AA.
AC   Q8NCP5; Q6IPT8; Q86VJ7; Q86XX5;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 44;
DE   AltName: Full=BTB/POZ domain-containing protein 15;
DE   AltName: Full=Zinc finger protein 851;
GN   Name=ZBTB44; Synonyms=BTBD15, ZNF851;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT46_HUMAN             Reviewed;         589 AA.
AC   Q86UZ6; E1P5K9; Q5JWJ3; Q6GMV4; Q9BQK3; Q9H3Z8; Q9H3Z9;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 46;
DE   AltName: Full=BTB-ZF protein expressed in effector lymphocytes;
DE            Short=BZEL;
DE   AltName: Full=BTB/POZ domain-containing protein 4;
DE   AltName: Full=Zinc finger protein 340;
GN   Name=ZBTB46; Synonyms=BTBD4, ZNF340;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:2001199; P:negative regulation of dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0030853; P:negative regulation of granulocyte differentiation; IEA:Ensembl.
DR   GO; GO:0045650; P:negative regulation of macrophage differentiation; IEA:Ensembl.
DR   GO; GO:0045656; P:negative regulation of monocyte differentiation; IEA:Ensembl.
DR   GO; GO:2001200; P:positive regulation of dendritic cell differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT45_HUMAN             Reviewed;         511 AA.
AC   Q96K62;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 45;
DE   AltName: Full=Zinc finger protein 499;
GN   Name=ZBTB45; Synonyms=ZNF499;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT47_HUMAN             Reviewed;         747 AA.
AC   Q9UFB7; H7BXD3; Q6ZSY6; Q8WTY8; Q9ULN0;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 47;
DE   AltName: Full=Zinc finger protein 651;
GN   Name=ZBTB47; Synonyms=KIAA1190, ZNF651;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT48_HUMAN             Reviewed;         688 AA.
AC   P10074; Q5SY19;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 48;
DE   AltName: Full=Krueppel-related zinc finger protein 3;
DE   AltName: Full=Protein HKR3;
DE   AltName: Full=Zinc finger protein 855;
GN   Name=ZBTB48; Synonyms=HKR3, ZNF855;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT49_HUMAN             Reviewed;         765 AA.
AC   Q6ZSB9; Q59FJ4; Q5EBN0; Q8TB80;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 49;
DE   AltName: Full=Zinc finger protein 509;
GN   Name=ZBTB49; Synonyms=ZNF509;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT7A_HUMAN             Reviewed;         584 AA.
AC   O95365; D6W619; O00456; Q14D41; Q5XG86;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 7A;
DE   AltName: Full=Factor binding IST protein 1;
DE            Short=FBI-1;
DE   AltName: Full=Factor that binds to inducer of short transcripts protein 1;
DE   AltName: Full=HIV-1 1st-binding protein 1;
DE   AltName: Full=Leukemia/lymphoma-related factor;
DE   AltName: Full=POZ and Krueppel erythroid myeloid ontogenic factor;
DE            Short=POK erythroid myeloid ontogenic factor;
DE            Short=Pokemon;
DE   AltName: Full=TTF-I-interacting peptide 21;
DE            Short=TIP21;
DE   AltName: Full=Zinc finger protein 857A;
GN   Name=ZBTB7A; Synonyms=FBI1, LRF, ZBTB7, ZNF857A;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0035035; F:histone acetyltransferase binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT7B_HUMAN             Reviewed;         539 AA.
AC   O15156; B4E3K5; D3DV83; J3KQQ3; Q68DR2; Q96EP2;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 7B;
DE   AltName: Full=Krueppel-related zinc finger protein cKrox;
DE            Short=hcKrox;
DE   AltName: Full=T-helper-inducing POZ/Krueppel-like factor;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 15;
DE   AltName: Full=Zinc finger protein 67 homolog;
DE            Short=Zfp-67;
DE   AltName: Full=Zinc finger protein 857B;
DE   AltName: Full=Zinc finger protein Th-POK;
GN   Name=ZBTB7B; Synonyms=ZBTB15, ZFP67, ZNF857B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007398; P:ectoderm development; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZBT7C_HUMAN             Reviewed;         619 AA.
AC   A1YPR0; O73453;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 7C;
DE   AltName: Full=Affected by papillomavirus DNA integration in ME180 cells protein 1;
DE            Short=APM-1;
DE   AltName: Full=Zinc finger and BTB domain-containing protein 36;
DE   AltName: Full=Zinc finger protein 857C;
GN   Name=ZBTB7C; Synonyms=APM1, ZBTB36, ZNF857C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZBT8A_HUMAN             Reviewed;         441 AA.
AC   Q96BR9; Q8IUL5; Q8IWR9; Q8N2Y5; Q96BX0;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 8A;
DE   AltName: Full=BTB/POZ and zinc-finger domain-containing factor;
DE   AltName: Full=BTB/POZ and zinc-finger domains factor on chromosome 1;
DE            Short=BOZ-F1;
GN   Name=ZBTB8A; Synonyms=BOZF1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBT8B_HUMAN             Reviewed;         495 AA.
AC   Q8NAP8; Q15DG5; Q5VXR5; Q69YT7;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 8B;
GN   Name=ZBTB8B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBTB1_HUMAN             Reviewed;         713 AA.
AC   Q9Y2K1; A8K6S8; Q86SW8;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 1;
GN   Name=ZBTB1; Synonyms=KIAA0997;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0030183; P:B cell differentiation; IEA:Ensembl.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0032825; P:positive regulation of natural killer cell differentiation; ISS:UniProtKB.
DR   GO; GO:2000176; P:positive regulation of pro-T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0045582; P:positive regulation of T cell differentiation; ISS:UniProtKB.
DR   GO; GO:0002711; P:positive regulation of T cell mediated immunity; ISS:UniProtKB.
DR   GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB.
DR   GO; GO:0033077; P:T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0048538; P:thymus development; ISS:UniProtKB.
//
ID   ZBTB2_HUMAN             Reviewed;         514 AA.
AC   Q8N680; A8K7C7; Q5SZ81; Q9P245;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 2;
GN   Name=ZBTB2; Synonyms=KIAA1483, ZNF437;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBTB3_HUMAN             Reviewed;         574 AA.
AC   Q9H5J0;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 3;
GN   Name=ZBTB3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBTB4_HUMAN             Reviewed;        1013 AA.
AC   Q9P1Z0; B3KVL6; Q7Z697; Q86XJ4; Q8N4V8;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 4;
DE   AltName: Full=KAISO-like zinc finger protein 1;
DE            Short=KAISO-L1;
GN   Name=ZBTB4; Synonyms=KIAA1538;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008327; F:methyl-CpG binding; IDA:UniProt.
DR   GO; GO:0010428; F:methyl-CpNpG binding; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProt.
DR   GO; GO:0019901; F:protein kinase binding; IPI:UniProt.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProt.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProt.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBTB5_HUMAN             Reviewed;         677 AA.
AC   O15062;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 5;
GN   Name=ZBTB5; Synonyms=KIAA0354;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBTB6_HUMAN             Reviewed;         424 AA.
AC   Q15916; A8K8N6;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 6;
DE   AltName: Full=Zinc finger protein 482;
DE   AltName: Full=Zinc finger protein with interaction domain;
GN   Name=ZBTB6; Synonyms=ZID, ZNF482;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZBTB9_HUMAN             Reviewed;         473 AA.
AC   Q96C00; A2AB19;
DE   RecName: Full=Zinc finger and BTB domain-containing protein 9;
GN   Name=ZBTB9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZC11A_HUMAN             Reviewed;         810 AA.
AC   O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 11A;
GN   Name=ZC3H11A; Synonyms=KIAA0663, ZC3HDC11A;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:UniProtKB.
//
ID   ZC12B_HUMAN             Reviewed;         836 AA.
AC   Q5HYM0; B2RTQ3; E9PAJ6; Q5H9C0;
DE   RecName: Full=Probable ribonuclease ZC3H12B;
DE            EC=3.1.-.-;
DE   AltName: Full=MCP-induced protein 2;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 12B;
GN   Name=ZC3H12B; Synonyms=CXorf32, MCPIP2;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZC12C_HUMAN             Reviewed;         883 AA.
AC   Q9C0D7; B4DI65; B4DR47;
DE   RecName: Full=Probable ribonuclease ZC3H12C;
DE            EC=3.1.-.-;
DE   AltName: Full=MCP-induced protein 3;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 12C;
GN   Name=ZC3H12C; Synonyms=KIAA1726, MCPIP3;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZC12A_HUMAN             Reviewed;         599 AA.
AC   Q5D1E8; D3DPT0; Q6I9Z1; Q9H5P1;
DE   RecName: Full=Ribonuclease ZC3H12A;
DE            EC=3.1.-.-;
DE   AltName: Full=MCP-induced protein 1;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 12A;
GN   Name=ZC3H12A; Synonyms=MCPIP, MCPIP1;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:BHF-UCL.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0032715; P:negative regulation of interleukin-6 production; IDA:BHF-UCL.
DR   GO; GO:0043031; P:negative regulation of macrophage activation; IC:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045019; P:negative regulation of nitric oxide biosynthetic process; IDA:BHF-UCL.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IDA:BHF-UCL.
DR   GO; GO:0010508; P:positive regulation of autophagy; IDA:BHF-UCL.
DR   GO; GO:0045600; P:positive regulation of fat cell differentiation; IDA:BHF-UCL.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:BHF-UCL.
DR   GO; GO:0010884; P:positive regulation of lipid storage; IDA:BHF-UCL.
DR   GO; GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IDA:BHF-UCL.
//
ID   ZC12D_HUMAN             Reviewed;         527 AA.
AC   A2A288; A1L178; B2RXF4; B7WNU7; B9ZZP9; B9ZZQ0; Q6ZRW2;
DE   RecName: Full=Probable ribonuclease ZC3H12D;
DE            EC=3.1.-.-;
DE   AltName: Full=MCP-induced protein 4;
DE   AltName: Full=Transformed follicular lymphoma;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 12D;
DE   AltName: Full=p34;
GN   Name=ZC3H12D; Synonyms=C6orf95, MCPIP4, TFL;
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
//
ID   ZC21A_HUMAN             Reviewed;         325 AA.
AC   Q96GY0; Q9Y372;
DE   RecName: Full=Zinc finger C2HC domain-containing protein 1A;
GN   Name=ZC2HC1A; Synonyms=C8orf70, FAM164A; ORFNames=CGI-62;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZC21B_HUMAN             Reviewed;         222 AA.
AC   Q5TFG8; B2RUZ7; Q5TFG9;
DE   RecName: Full=Zinc finger C2HC domain-containing protein 1B;
GN   Name=ZC2HC1B; Synonyms=C6orf94, FAM164B;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZC21C_HUMAN             Reviewed;         456 AA.
AC   Q53FD0; E9PJQ0; Q9BTA8; Q9H5S9;
DE   RecName: Full=Zinc finger C2HC domain-containing protein 1C;
GN   Name=ZC2HC1C; Synonyms=C14orf140, FAM164C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZC3H1_HUMAN             Reviewed;        1989 AA.
AC   O60293; Q6GMU1; Q6P2S9; Q6ZV36; Q96BE7;
DE   RecName: Full=Zinc finger C3H1 domain-containing protein;
DE   AltName: Full=Coiled-coil domain-containing protein 131;
DE   AltName: Full=Proline/serine-rich coiled-coil protein 2;
GN   Name=ZFC3H1; Synonyms=CCDC131, KIAA0546, PSRC2;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
//
ID   ZC3H4_HUMAN             Reviewed;        1303 AA.
AC   Q9UPT8; Q9Y420;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 4;
GN   Name=ZC3H4; Synonyms=C19orf7, KIAA1064;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   ZC3H3_HUMAN             Reviewed;         948 AA.
AC   Q8IXZ2; Q14163; Q8N4E2; Q9BUS4;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 3;
GN   Name=ZC3H3; Synonyms=KIAA0150, ZC3HDC3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
DR   GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:UniProtKB.
DR   GO; GO:0010793; P:regulation of mRNA export from nucleus; IMP:UniProtKB.
//
ID   ZC3H6_HUMAN             Reviewed;        1189 AA.
AC   P61129; A9JR71; Q6ZW96;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 6;
GN   Name=ZC3H6; Synonyms=KIAA2035, ZC3HDC6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZC3H8_HUMAN             Reviewed;         291 AA.
AC   Q8N5P1; Q9BZ75;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 8;
GN   Name=ZC3H8; Synonyms=ZC3HDC8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0033085; P:negative regulation of T cell differentiation in thymus; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0070245; P:positive regulation of thymocyte apoptotic process; IMP:UniProtKB.
DR   GO; GO:0046677; P:response to antibiotic; IDA:UniProtKB.
DR   GO; GO:0043029; P:T cell homeostasis; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZC3HD_HUMAN             Reviewed;        1668 AA.
AC   Q5T200; A2A323; O94936; Q5T1Z9; Q7Z7J3; Q8NDT6; Q9H0L6;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 13;
GN   Name=ZC3H13; Synonyms=KIAA0853;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ZC3HA_HUMAN             Reviewed;         434 AA.
AC   Q96K80;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 10;
GN   Name=ZC3H10; Synonyms=ZC3HDC10;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ZC3HE_HUMAN             Reviewed;         736 AA.
AC   Q6PJT7; A8MY46; B4E2H4; G3V5R4; Q6MZU4; Q6PJ32; Q6PUI6; Q6PUI8;
AC   Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 14;
DE   AltName: Full=Mammalian suppressor of tau pathology-2;
DE            Short=MSUT-2;
DE   AltName: Full=Renal carcinoma antigen NY-REN-37;
GN   Name=ZC3H14;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
//
ID   ZC3HF_HUMAN             Reviewed;         426 AA.
AC   Q8WU90; D3DPG7; Q5QTQ4; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 15;
DE   AltName: Full=DRG family-regulatory protein 1;
DE   AltName: Full=Likely ortholog of mouse immediate early response erythropoietin 4;
GN   Name=ZC3H15; Synonyms=DFRP1, LEREPO4;
GN   ORFNames=HSPC303, HT010, MSTP012, PP730;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IEA:Ensembl.
//
ID   ZC4H2_HUMAN             Reviewed;         224 AA.
AC   Q9NQZ6; B2RDC2; B3KVZ5; B4DED0; E7EM74; G3V1L3; Q53H73; Q5JTF9;
AC   Q9H9C3; Q9H9H7; Q9ULQ4;
DE   RecName: Full=Zinc finger C4H2 domain-containing protein;
DE   AltName: Full=Hepatocellular carcinoma-associated antigen 127;
GN   Name=ZC4H2; Synonyms=HCA127, KIAA1166;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007399; P:nervous system development; IDA:UniProtKB.
DR   GO; GO:0007528; P:neuromuscular junction development; ISS:UniProtKB.
DR   GO; GO:0021522; P:spinal cord motor neuron differentiation; ISS:UniProtKB.
//
ID   ZCCHL_HUMAN             Reviewed;         300 AA.
AC   Q96H79; Q8WUD9;
DE   RecName: Full=Zinc finger CCCH-type antiviral protein 1-like;
GN   Name=ZC3HAV1L; Synonyms=C7orf39;
//
ID   ZCC18_HUMAN             Reviewed;         403 AA.
AC   P0CG32;
DE   RecName: Full=Putative zinc finger CCHC domain-containing protein 18;
GN   Name=ZCCHC18;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCCHV_HUMAN             Reviewed;         902 AA.
AC   Q7Z2W4; A4D1R2; A4D1S4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7;
DE   RecName: Full=Zinc finger CCCH-type antiviral protein 1;
DE   AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 13;
DE            Short=ARTD13;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 2;
DE   AltName: Full=Zinc finger antiviral protein;
DE            Short=ZAP;
GN   Name=ZC3HAV1; Synonyms=ZC3HDC2; ORFNames=PRO1677;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0071360; P:cellular response to exogenous dsRNA; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; IDA:UniProtKB.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0032727; P:positive regulation of interferon-alpha production; IDA:UniProtKB.
DR   GO; GO:0032728; P:positive regulation of interferon-beta production; IDA:UniProtKB.
DR   GO; GO:0061014; P:positive regulation of mRNA catabolic process; IDA:UniProtKB.
DR   GO; GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.
DR   GO; GO:0032481; P:positive regulation of type I interferon production; IEA:Ensembl.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
//
ID   ZCH10_HUMAN             Reviewed;         192 AA.
AC   Q8TBK6; Q9NXR4;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 10;
GN   Name=ZCCHC10;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCH12_HUMAN             Reviewed;         402 AA.
AC   Q6PEW1; B3KV48; Q6PID5; Q8N1C1;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 12;
DE   AltName: Full=Smad-interacting zinc finger protein 1;
GN   Name=ZCCHC12; Synonyms=SIZN1;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IBA:RefGenome.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030509; P:BMP signaling pathway; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZCH13_HUMAN             Reviewed;         166 AA.
AC   Q8WW36;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 13;
GN   Name=ZCCHC13;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCH14_HUMAN             Reviewed;         949 AA.
AC   Q8WYQ9; D3DUN1; O60324; Q3MJD8; Q9UFP0;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 14;
DE   AltName: Full=BDG-29;
GN   Name=ZCCHC14; Synonyms=KIAA0579;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCH16_HUMAN             Reviewed;         310 AA.
AC   Q6ZR62; B2RPG1;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 16;
DE   AltName: Full=Mammalian retrotransposon-derived protein 4;
GN   Name=ZCCHC16; Synonyms=MAR3, MART4;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCH18_HUMAN             Reviewed;         953 AA.
AC   Q86VM9; Q96DG4; Q96MP7;
DE   RecName: Full=Zinc finger CCCH domain-containing protein 18;
DE   AltName: Full=Nuclear protein NHN1;
GN   Name=ZC3H18; Synonyms=NHN1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   ZCH24_HUMAN             Reviewed;         241 AA.
AC   Q8N2G6; Q5U5T9; Q8TAG0;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 24;
GN   Name=ZCCHC24; Synonyms=C10orf56;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCH23_HUMAN             Reviewed;         131 AA.
AC   Q6ZST2;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 23;
GN   Name=ZCCHC23;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCHC2_HUMAN             Reviewed;        1178 AA.
AC   Q9C0B9; Q8N3S1; Q9NXF6;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 2;
GN   Name=ZCCHC2; Synonyms=KIAA1744;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCHC3_HUMAN             Reviewed;         404 AA.
AC   Q9NUD5; Q6NT79;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 3;
GN   Name=ZCCHC3; Synonyms=C20orf99;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCHC4_HUMAN             Reviewed;         513 AA.
AC   Q9H5U6; B2RXF6; B4DRD8; B7ZW20; Q5IW78; Q96AN7;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 4;
GN   Name=ZCCHC4;
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCHC5_HUMAN             Reviewed;         475 AA.
AC   Q8N8U3; B2RMZ0; Q5JQE9;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 5;
GN   Name=ZCCHC5;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCHC7_HUMAN             Reviewed;         543 AA.
AC   Q8N3Z6; B2RCI4; D3DRQ0; Q5T0Q8; Q5T0Q9; Q5T0R0; Q8N2M1; Q8N4J2;
AC   Q8TBK8; Q9H648; Q9P0F0;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 7;
DE   AltName: Full=TRAMP-like complex RNA-binding factor ZCCHC7;
GN   Name=ZCCHC7; ORFNames=HSPC086;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCHC8_HUMAN             Reviewed;         707 AA.
AC   Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 8;
DE   AltName: Full=TRAMP-like complex RNA-binding factor ZCCHC8;
GN   Name=ZCCHC8;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IC:UniProtKB.
//
ID   ZCHC9_HUMAN             Reviewed;         271 AA.
AC   Q8N567; B2RAE7; Q9H027;
DE   RecName: Full=Zinc finger CCHC domain-containing protein 9;
GN   Name=ZCCHC9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   ZCPW1_HUMAN             Reviewed;         648 AA.
AC   Q9H0M4; A8MVF5; B4DUQ2; Q8NA98; Q9BUD0; Q9NWF7;
DE   RecName: Full=Zinc finger CW-type PWWP domain protein 1;
GN   Name=ZCWPW1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCPW2_HUMAN             Reviewed;         356 AA.
AC   Q504Y3;
DE   RecName: Full=Zinc finger CW-type PWWP domain protein 2;
GN   Name=ZCWPW2;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZCRB1_HUMAN             Reviewed;         217 AA.
AC   Q8TBF4; Q6PJX0; Q96TA6;
DE   RecName: Full=Zinc finger CCHC-type and RNA-binding motif-containing protein 1;
DE   AltName: Full=U11/U12 small nuclear ribonucleoprotein 31 kDa protein;
DE            Short=U11/U12 snRNP 31 kDa protein;
DE            Short=U11/U12-31K;
GN   Name=ZCRB1;
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   ZDBF2_HUMAN             Reviewed;        2354 AA.
AC   Q9HCK1; Q6ZNP7; Q6ZSN8;
DE   RecName: Full=DBF4-type zinc finger-containing protein 2;
GN   Name=ZDBF2; Synonyms=KIAA1571;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZDH11_HUMAN             Reviewed;         412 AA.
AC   Q9H8X9;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC11;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 11;
DE            Short=DHHC-11;
DE   AltName: Full=Zinc finger protein 399;
GN   Name=ZDHHC11; Synonyms=ZNF399;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZDH12_HUMAN             Reviewed;         267 AA.
AC   Q96GR4; A6NH95; B2RE03; Q5T265; Q5T267; Q5T268; Q86VT5; Q96T09;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC12;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 12;
DE            Short=DHHC-12;
DE   AltName: Full=Zinc finger protein 400;
GN   Name=ZDHHC12; Synonyms=ZNF400; ORFNames=PSEC0008;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDH13_HUMAN             Reviewed;         622 AA.
AC   Q8IUH4; Q7Z2D3; Q86VK2; Q9NV30; Q9NV99;
DE   RecName: Full=Palmitoyltransferase ZDHHC13;
DE            EC=2.3.1.225;
DE   AltName: Full=Huntingtin-interacting protein 14-related protein;
DE            Short=HIP14-related protein;
DE   AltName: Full=Huntingtin-interacting protein HIP3RP;
DE   AltName: Full=Putative MAPK-activating protein PM03;
DE   AltName: Full=Putative NF-kappa-B-activating protein 209;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 13;
DE            Short=DHHC-13;
GN   Name=ZDHHC13; Synonyms=HIP14L, HIP3RP;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0016409; F:palmitoyltransferase activity; ISS:UniProtKB.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008152; P:metabolic process; ISS:GOC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   ZDH14_HUMAN             Reviewed;         488 AA.
AC   Q8IZN3; A6NDB7; Q5JS07; Q5JS08; Q6PHS4; Q8IZN2; Q9H7F1;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC14;
DE            EC=2.3.1.225;
DE   AltName: Full=NEW1 domain-containing protein;
DE            Short=NEW1CP;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 14;
DE            Short=DHHC-14;
GN   Name=ZDHHC14;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDH15_HUMAN             Reviewed;         337 AA.
AC   Q96MV8; B3KVG7; Q3SY30; Q6UWH3;
DE   RecName: Full=Palmitoyltransferase ZDHHC15;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 15;
DE            Short=DHHC-15;
GN   Name=ZDHHC15; ORFNames=UNQ1969/PRO4501;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045184; P:establishment of protein localization; IEA:Ensembl.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
DR   GO; GO:0016188; P:synaptic vesicle maturation; IEA:Ensembl.
//
ID   ZDH16_HUMAN             Reviewed;         377 AA.
AC   Q969W1; D3DR52; D3DR53; D3DR54; Q5JTG7; Q5JTH0; Q8N4Z6; Q8WY84;
AC   Q9BSV3;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC16;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 16;
DE            Short=DHHC-16;
GN   Name=ZDHHC16; ORFNames=UNQ2570/PRO6258;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDH17_HUMAN             Reviewed;         632 AA.
AC   Q8IUH5; B4DR39; O75407; Q7Z2I0; Q86W89; Q86YK0; Q9P088; Q9UPZ8;
DE   RecName: Full=Palmitoyltransferase ZDHHC17;
DE            EC=2.3.1.225;
DE   AltName: Full=Huntingtin yeast partner H;
DE   AltName: Full=Huntingtin-interacting protein 14;
DE            Short=HIP-14;
DE   AltName: Full=Huntingtin-interacting protein 3;
DE            Short=HIP-3;
DE   AltName: Full=Huntingtin-interacting protein H;
DE   AltName: Full=Putative MAPK-activating protein PM11;
DE   AltName: Full=Putative NF-kappa-B-activating protein 205;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 17;
DE            Short=DHHC-17;
GN   Name=ZDHHC17; Synonyms=HIP14, HIP3, HYPH, KIAA0946; ORFNames=HSPC294;
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IDA:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042953; P:lipoprotein transport; IDA:UniProtKB.
DR   GO; GO:0015693; P:magnesium ion transport; IDA:GOC.
DR   GO; GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IMP:GOC.
//
ID   ZDH18_HUMAN             Reviewed;         388 AA.
AC   Q9NUE0; A6NHY9; Q5JYH0; Q9H020;
DE   RecName: Full=Palmitoyltransferase ZDHHC18;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 18;
DE            Short=DHHC-18;
GN   Name=ZDHHC18;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0034613; P:cellular protein localization; IEA:Ensembl.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDH19_HUMAN             Reviewed;         309 AA.
AC   Q8WVZ1; A8MSY6;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC19;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 19;
DE            Short=DHHC-19;
GN   Name=ZDHHC19;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZDH20_HUMAN             Reviewed;         365 AA.
AC   Q5W0Z9; A8MTV9; C9JG20; I6L9D4; Q6NVU8;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC20;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 20;
DE            Short=DHHC-20;
GN   Name=ZDHHC20;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDH21_HUMAN             Reviewed;         265 AA.
AC   Q8IVQ6; A8KA95; D3DRI7; Q5VWG1;
DE   RecName: Full=Palmitoyltransferase ZDHHC21;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 21;
DE            Short=DHHC-21;
GN   Name=ZDHHC21;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR   GO; GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.
DR   GO; GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IMP:UniProtKB.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
DR   GO; GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.
DR   GO; GO:0048733; P:sebaceous gland development; IEA:Ensembl.
DR   GO; GO:0044281; P:small molecule metabolic process; TAS:Reactome.
//
ID   ZDH22_HUMAN             Reviewed;         263 AA.
AC   Q8N966; A6NH02; B7Z2L5; Q149P4;
DE   RecName: Full=Palmitoyltransferase ZDHHC22;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 22;
DE            Short=DHHC-22;
DE            Short=zDHHC22;
GN   Name=ZDHHC22; Synonyms=C14orf59;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0018345; P:protein palmitoylation; IEA:Ensembl.
//
ID   ZDH23_HUMAN             Reviewed;         409 AA.
AC   Q8IYP9; D3DN76;
DE   RecName: Full=Palmitoyltransferase ZDHHC23;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 23;
DE            Short=DHHC-23;
DE            Short=zDHHC23;
GN   Name=ZDHHC23;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0018345; P:protein palmitoylation; IEA:Ensembl.
//
ID   ZDH24_HUMAN             Reviewed;         284 AA.
AC   Q6UX98; Q6PEW7; Q9BSJ0;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC24;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 24;
DE            Short=DHHC-24;
GN   Name=ZDHHC24; ORFNames=UNQ2528/PRO6027;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZDHC1_HUMAN             Reviewed;         485 AA.
AC   Q8WTX9; O15461;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC1;
DE            EC=2.3.1.225;
DE   AltName: Full=DHHC domain-containing cysteine-rich protein 1;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 1;
DE            Short=DHHC-1;
DE   AltName: Full=Zinc finger protein 377;
GN   Name=ZDHHC1; Synonyms=C16orf1, ZNF377;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDHC2_HUMAN             Reviewed;         367 AA.
AC   Q9UIJ5; D3DSP5;
DE   RecName: Full=Palmitoyltransferase ZDHHC2;
DE            EC=2.3.1.225;
DE   AltName: Full=Reduced expression associated with metastasis protein;
DE            Short=Ream;
DE   AltName: Full=Reduced expression in cancer protein;
DE            Short=Rec;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 2;
DE            Short=DHHC-2;
DE   AltName: Full=Zinc finger protein 372;
GN   Name=ZDHHC2; Synonyms=REAM, REC, ZNF372;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDHC3_HUMAN             Reviewed;         299 AA.
AC   Q9NYG2; Q53A17; Q96BL0;
DE   RecName: Full=Palmitoyltransferase ZDHHC3;
DE            EC=2.3.1.225;
DE   AltName: Full=Protein DHHC1;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 3;
DE            Short=DHHC-3;
DE   AltName: Full=Zinc finger protein 373;
GN   Name=ZDHHC3; Synonyms=ZNF373; ORFNames=HSD49;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
DR   GO; GO:0006605; P:protein targeting; IEA:Ensembl.
//
ID   ZDHC4_HUMAN             Reviewed;         344 AA.
AC   Q9NPG8; A4D2N9; Q53EV7; Q6FIB5; Q9H0R9;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC4;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 4;
DE            Short=DHHC-4;
DE   AltName: Full=Zinc finger protein 374;
GN   Name=ZDHHC4; Synonyms=ZNF374; ORFNames=DC1, UNQ5787/PRO19576;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZDHC5_HUMAN             Reviewed;         715 AA.
AC   Q9C0B5; Q2TGF0; Q6ZMF0; Q8TAK8; Q9H923; Q9UFI7;
DE   RecName: Full=Palmitoyltransferase ZDHHC5;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 5;
DE            Short=DHHC-5;
DE   AltName: Full=Zinc finger protein 375;
GN   Name=ZDHHC5; Synonyms=KIAA1748, ZNF375;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDHC6_HUMAN             Reviewed;         413 AA.
AC   Q9H6R6; D3DRB6; Q53G45; Q96IV7; Q9H605;
DE   RecName: Full=Palmitoyltransferase ZDHHC6;
DE            EC=2.3.1.225;
DE   AltName: Full=Transmembrane protein H4;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 6;
DE            Short=DHHC-6;
DE   AltName: Full=Zinc finger protein 376;
GN   Name=ZDHHC6; Synonyms=ZNF376;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDHC7_HUMAN             Reviewed;         308 AA.
AC   Q9NXF8; D3DUM1; Q8WV42; Q9NVD8;
DE   RecName: Full=Palmitoyltransferase ZDHHC7;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 7;
DE            Short=DHHC-7;
DE   AltName: Full=Zinc finger protein 370;
GN   Name=ZDHHC7; Synonyms=ZNF370;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IMP:UniProtKB.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDHC8_HUMAN             Reviewed;         765 AA.
AC   Q9ULC8; Q2TGE9; Q6ICL1; Q6ZNF5; Q7Z6L9;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC8;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 8;
DE            Short=DHHC-8;
DE   AltName: Full=Zinc finger protein 378;
GN   Name=ZDHHC8; Synonyms=KIAA1292, ZDHHCL1, ZNF378;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZDHC9_HUMAN             Reviewed;         364 AA.
AC   Q9Y397; B4F6G2; D3DTF9; Q59EK4; Q5JSW5; Q8WWS7; Q9BPY4; Q9NSP0;
AC   Q9NVL0; Q9NVR6;
DE   RecName: Full=Palmitoyltransferase ZDHHC9;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 9;
DE            Short=DHHC-9;
DE            Short=DHHC9;
DE   AltName: Full=Zinc finger protein 379;
DE   AltName: Full=Zinc finger protein 380;
GN   Name=ZDHHC9; Synonyms=CXorf11, ZDHHC10, ZNF379, ZNF380;
GN   ORFNames=CGI-89, UNQ261/PRO298;
DR   GO; GO:0016409; F:palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043849; F:Ras palmitoyltransferase activity; IDA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0018230; P:peptidyl-L-cysteine S-palmitoylation; IDA:UniProt.
DR   GO; GO:0018345; P:protein palmitoylation; IDA:UniProt.
//
ID   ZEB1_HUMAN              Reviewed;        1124 AA.
AC   P37275; B4DJV0; B4DUW9; E9PCM7; F5H4I8; Q12924; Q13800; Q2KJ05;
AC   Q5T968; Q5VZ84; Q8NB68;
DE   RecName: Full=Zinc finger E-box-binding homeobox 1;
DE   AltName: Full=NIL-2-A zinc finger protein;
DE   AltName: Full=Negative regulator of IL2;
DE   AltName: Full=Transcription factor 8;
DE            Short=TCF-8;
GN   Name=ZEB1; Synonyms=AREB6, TCF8;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0070888; F:E-box binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0051216; P:cartilage development; IEA:Ensembl.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071230; P:cellular response to amino acid stimulus; IEA:Ensembl.
DR   GO; GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEA:Ensembl.
DR   GO; GO:0090103; P:cochlea morphogenesis; IEA:Ensembl.
DR   GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Ensembl.
DR   GO; GO:0048704; P:embryonic skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0006955; P:immune response; TAS:ProtInc.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
DR   GO; GO:0030857; P:negative regulation of epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; IEA:Ensembl.
DR   GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0010464; P:regulation of mesenchymal cell proliferation; IEA:Ensembl.
DR   GO; GO:0051150; P:regulation of smooth muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0033081; P:regulation of T cell differentiation in thymus; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0014823; P:response to activity; IEA:Ensembl.
DR   GO; GO:0031667; P:response to nutrient levels; IEA:Ensembl.
DR   GO; GO:0048752; P:semicircular canal morphogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZEB2_HUMAN              Reviewed;        1214 AA.
AC   O60315; A0JP09; B7Z2P2; F5H814; Q9UED1;
DE   RecName: Full=Zinc finger E-box-binding homeobox 2;
DE   AltName: Full=Smad-interacting protein 1;
DE            Short=SMADIP1;
DE   AltName: Full=Zinc finger homeobox protein 1b;
GN   Name=ZEB2; Synonyms=KIAA0569, SIP1, ZFHX1B, ZFX1B;
GN   ORFNames=HRIHFB2411;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019208; F:phosphatase regulator activity; NAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
DR   GO; GO:0021766; P:hippocampus development; IEA:Ensembl.
DR   GO; GO:0007399; P:nervous system development; NAS:UniProtKB.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0043507; P:positive regulation of JUN kinase activity; IEA:Ensembl.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZEP2_HUMAN              Reviewed;        2446 AA.
AC   P31629; Q02646; Q5THT5; Q9NS05;
DE   RecName: Full=Transcription factor HIVEP2;
DE   AltName: Full=Human immunodeficiency virus type I enhancer-binding protein 2;
DE            Short=HIV-EP2;
DE   AltName: Full=MHC-binding protein 2;
DE            Short=MBP-2;
GN   Name=HIVEP2;
DR   GO; GO:0003677; F:DNA binding; TAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZEP1_HUMAN              Reviewed;        2718 AA.
AC   P15822; B2RTU3; Q14122; Q5MPB1; Q5VW60;
DE   RecName: Full=Zinc finger protein 40;
DE   AltName: Full=Cirhin interaction protein;
DE            Short=CIRIP;
DE   AltName: Full=Gate keeper of apoptosis-activating protein;
DE            Short=GAAP;
DE   AltName: Full=Human immunodeficiency virus type I enhancer-binding protein 1;
DE            Short=HIV-EP1;
DE   AltName: Full=Major histocompatibility complex-binding protein 1;
DE            Short=MBP-1;
DE   AltName: Full=Positive regulatory domain II-binding factor 1;
DE            Short=PRDII-BF1;
GN   Name=HIVEP1; Synonyms=ZNF40;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZEP3_HUMAN              Reviewed;        2406 AA.
AC   Q5T1R4; A7YY91; Q5T1R5; Q9BZS0; Q9HCL7;
DE   RecName: Full=Transcription factor HIVEP3;
DE   AltName: Full=Human immunodeficiency virus type I enhancer-binding protein 3;
DE   AltName: Full=Kappa-B and V(D)J recombination signal sequences-binding protein;
DE   AltName: Full=Kappa-binding protein 1;
DE            Short=KBP-1;
DE   AltName: Full=Zinc finger protein ZAS3;
GN   Name=HIVEP3; Synonyms=KBP1, KIAA1555, KRC, ZAS3;
DR   GO; GO:0003677; F:DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZER1_HUMAN              Reviewed;         766 AA.
AC   Q7Z7L7; O00156; Q5T272; Q5T273;
DE   RecName: Full=Protein zer-1 homolog;
DE   AltName: Full=Hzyg;
DE   AltName: Full=Zyg-11 homolog B-like protein;
GN   Name=ZER1; Synonyms=C9orf60, ZYG, ZYG11BL;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IMP:GOC.
DR   GO; GO:0051438; P:regulation of ubiquitin-protein ligase activity; IMP:UniProtKB.
//
ID   ZF64A_HUMAN             Reviewed;         681 AA.
AC   Q9NPA5; Q9NTS7; Q9NVH4;
DE   RecName: Full=Zinc finger protein 64 homolog, isoforms 1 and 2;
DE            Short=Zfp-64;
DE   AltName: Full=Zinc finger protein 338;
GN   Name=ZFP64; Synonyms=ZNF338;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZF64B_HUMAN             Reviewed;         645 AA.
AC   Q9NTW7; A2A2N4; Q53H69; Q53XQ1; Q5JWM0; Q5JWM1; Q8WU98; Q9H9P1;
DE   RecName: Full=Zinc finger protein 64 homolog, isoforms 3 and 4;
DE            Short=Zfp-64;
DE   AltName: Full=Zinc finger protein 338;
GN   Name=ZFP64; Synonyms=ZNF338;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZF69B_HUMAN             Reviewed;         534 AA.
AC   Q9UJL9; Q5QPL4;
DE   RecName: Full=Zinc finger protein ZFP69B;
DE   AltName: Full=Zinc finger protein 643;
GN   Name=ZFP69B; Synonyms=ZNF643;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFAN1_HUMAN             Reviewed;         268 AA.
AC   Q8TCF1; E5RIG0; E5RJ99; Q658R7; Q6IA32; Q6PGQ6; Q9H810;
DE   RecName: Full=AN1-type zinc finger protein 1;
GN   Name=ZFAND1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFAN3_HUMAN             Reviewed;         227 AA.
AC   Q9H8U3; Q5SZZ0; Q5SZZ1;
DE   RecName: Full=AN1-type zinc finger protein 3;
DE   AltName: Full=Testis-expressed sequence 27;
GN   Name=ZFAND3; Synonyms=TEX27;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFAN4_HUMAN             Reviewed;         727 AA.
AC   Q86XD8; A8K8V4; B2RAX2; Q5VVY5;
DE   RecName: Full=AN1-type zinc finger protein 4;
DE   AltName: Full=AN1-type zinc finger and ubiquitin domain-containing protein-like 1;
GN   Name=ZFAND4; Synonyms=ANUBL1;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFAN5_HUMAN             Reviewed;         213 AA.
AC   O76080; A8K484;
DE   RecName: Full=AN1-type zinc finger protein 5;
DE   AltName: Full=Zinc finger A20 domain-containing protein 2;
DE   AltName: Full=Zinc finger protein 216;
GN   Name=ZFAND5; Synonyms=ZA20D2, ZNF216;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060324; P:face development; IEA:Ensembl.
DR   GO; GO:0010761; P:fibroblast migration; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0003016; P:respiratory system process; IEA:Ensembl.
DR   GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl.
DR   GO; GO:0048745; P:smooth muscle tissue development; IEA:Ensembl.
DR   GO; GO:0001944; P:vasculature development; IEA:Ensembl.
//
ID   ZFAN6_HUMAN             Reviewed;         208 AA.
AC   Q6FIF0; D3DW92; D3DW94; O95792; Q9BQF7; Q9GZY3;
DE   RecName: Full=AN1-type zinc finger protein 6;
DE   AltName: Full=Associated with PRK1 protein;
DE   AltName: Full=Zinc finger A20 domain-containing protein 3;
GN   Name=ZFAND6; Synonyms=AWP1, ZA20D3; ORFNames=HT032;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IMP:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0006625; P:protein targeting to peroxisome; ISS:UniProtKB.
DR   GO; GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
//
ID   ZFAT_HUMAN              Reviewed;        1243 AA.
AC   Q9P243; B7ZL15; E9PER3; Q3MIM5; Q6PJ01; Q75PJ6; Q75PJ7; Q75PJ9;
AC   Q86X64;
DE   RecName: Full=Zinc finger protein ZFAT;
DE   AltName: Full=Zinc finger gene in AITD susceptibility region;
DE   AltName: Full=Zinc finger protein 406;
GN   Name=ZFAT; Synonyms=KIAA1485, ZFAT1, ZNF406;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
DR   GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl.
DR   GO; GO:0060712; P:spongiotrophoblast layer development; IEA:Ensembl.
//
ID   ZFHX2_HUMAN             Reviewed;        2572 AA.
AC   Q9C0A1; Q9UPU6;
DE   RecName: Full=Zinc finger homeobox protein 2;
DE   AltName: Full=Zinc finger homeodomain protein 2;
DE            Short=ZFH-2;
GN   Name=ZFHX2; Synonyms=KIAA1056, KIAA1762, ZNF409;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030534; P:adult behavior; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFHX3_HUMAN             Reviewed;        3703 AA.
AC   Q15911; D3DWS8; O15101; Q13719;
DE   RecName: Full=Zinc finger homeobox protein 3;
DE   AltName: Full=AT motif-binding factor 1;
DE   AltName: Full=AT-binding transcription factor 1;
DE   AltName: Full=Alpha-fetoprotein enhancer-binding protein;
DE   AltName: Full=Zinc finger homeodomain protein 3;
DE            Short=ZFH-3;
GN   Name=ZFHX3; Synonyms=ATBF1;
DR   GO; GO:0019899; F:enzyme binding; IPI:UniProtKB.
DR   GO; GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   GO; GO:0007050; P:cell cycle arrest; IEA:Ensembl.
DR   GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR   GO; GO:0045662; P:negative regulation of myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045663; P:positive regulation of myoblast differentiation; IDA:UniProtKB.
DR   GO; GO:0045664; P:regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZFHX4_HUMAN             Reviewed;        3567 AA.
AC   Q86UP3; G3V138; Q18PS0; Q6ZN20;
DE   RecName: Full=Zinc finger homeobox protein 4;
DE   AltName: Full=Zinc finger homeodomain protein 4;
DE            Short=ZFH-4;
GN   Name=ZFHX4;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFN2A_HUMAN             Reviewed;         145 AA.
AC   Q8N6M9; A4D220;
DE   RecName: Full=AN1-type zinc finger protein 2A;
GN   Name=ZFAND2A;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFN2B_HUMAN             Reviewed;         257 AA.
AC   Q8WV99; Q8NB98;
DE   RecName: Full=AN1-type zinc finger protein 2B;
DE   AltName: Full=Arsenite-inducible RNA-associated protein-like protein;
DE            Short=AIRAP-like protein;
GN   Name=ZFAND2B; Synonyms=AIRAPL;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFP14_HUMAN             Reviewed;         533 AA.
AC   Q9HCL3; A7MD23;
DE   RecName: Full=Zinc finger protein 14 homolog;
DE            Short=Zfp-14;
DE   AltName: Full=Zinc finger protein 531;
GN   Name=ZFP14; Synonyms=KIAA1559, ZNF531;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP1_HUMAN              Reviewed;         407 AA.
AC   Q6P2D0; A8K5Q7; B4DKG9; Q8N188; Q8N9F9;
DE   RecName: Full=Zinc finger protein 1 homolog;
DE            Short=Zfp-1;
DE   AltName: Full=Zinc finger protein 475;
GN   Name=ZFP1; Synonyms=ZNF475;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP28_HUMAN             Reviewed;         868 AA.
AC   Q8NHY6; A0JNV6; Q9BY30; Q9P2B6;
DE   RecName: Full=Zinc finger protein 28 homolog;
DE            Short=Zfp-28;
DE   AltName: Full=Krueppel-like zinc finger factor X6;
GN   Name=ZFP28; Synonyms=KIAA1431;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP2_HUMAN              Reviewed;         461 AA.
AC   Q6ZN57; A5PLN5; B7ZM23; Q9H6Z6;
DE   RecName: Full=Zinc finger protein 2 homolog;
DE            Short=Zfp-2;
DE   AltName: Full=Zinc finger protein 751;
GN   Name=ZFP2; Synonyms=ZNF751;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP30_HUMAN             Reviewed;         519 AA.
AC   Q9Y2G7; Q58EY8;
DE   RecName: Full=Zinc finger protein 30 homolog;
DE            Short=Zfp-30;
DE   AltName: Full=Zinc finger protein 745;
GN   Name=ZFP30; Synonyms=KIAA0961, ZNF745;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP37_HUMAN             Reviewed;         630 AA.
AC   Q9Y6Q3; A0AVJ9; B4DVX4; Q5T7Q4;
DE   RecName: Full=Zinc finger protein 37 homolog;
DE            Short=Zfp-37;
GN   Name=ZFP37;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP3_HUMAN              Reviewed;         502 AA.
AC   Q96NJ6; A5PLL4;
DE   RecName: Full=Zinc finger protein 3 homolog;
DE            Short=Zfp-3;
DE   AltName: Full=Zinc finger protein 752;
GN   Name=ZFP3; Synonyms=ZNF752;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP41_HUMAN             Reviewed;         198 AA.
AC   Q8N8Y5; D3DWJ5;
DE   RecName: Full=Zinc finger protein 41 homolog;
DE            Short=Zfp-41;
GN   Name=ZFP41;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP42_HUMAN             Reviewed;         310 AA.
AC   Q96MM3; D3DP65; Q8WXE2;
DE   RecName: Full=Zinc finger protein 42 homolog;
DE            Short=Zfp-42;
DE   AltName: Full=Reduced expression protein 1;
DE            Short=REX-1;
DE            Short=hREX-1;
DE   AltName: Full=Zinc finger protein 754;
GN   Name=ZFP42; Synonyms=REX1, ZNF754;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008585; P:female gonad development; IEP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0008584; P:male gonad development; IEP:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; NAS:UniProtKB.
DR   GO; GO:2000653; P:regulation of genetic imprinting; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP57_HUMAN             Reviewed;         452 AA.
AC   Q9NU63; B0S894; B0V254; B2RXJ7; Q5SSB1;
DE   RecName: Full=Zinc finger protein 57 homolog;
DE            Short=Zfp-57;
DE   AltName: Full=Zinc finger protein 698;
GN   Name=ZFP57; Synonyms=C6orf40, ZNF698;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043045; P:DNA methylation involved in embryo development; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP62_HUMAN             Reviewed;         900 AA.
AC   Q8NB50; B4DIP6; B4E0N3; B5MDX6; B7ZVZ2; B9EIP6; E9PFT8; J3QTA9;
DE   RecName: Full=Zinc finger protein 62 homolog;
DE            Short=Zfp-62;
GN   Name=ZFP62;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP69_HUMAN             Reviewed;         526 AA.
AC   Q49AA0; Q5SWM5; Q6ZWK8;
DE   RecName: Full=Zinc finger protein ZFP69;
DE   AltName: Full=Zinc finger protein 642;
GN   Name=ZFP69; Synonyms=ZNF642;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP82_HUMAN             Reviewed;         532 AA.
AC   Q8N141; Q8NC63; Q8TF53;
DE   RecName: Full=Zinc finger protein 82 homolog;
DE            Short=Zfp-82;
DE   AltName: Full=Zinc finger protein 545;
GN   Name=ZFP82; Synonyms=KIAA1948, ZNF545;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP90_HUMAN             Reviewed;         636 AA.
AC   Q8TF47; B2RU00; B3KVE7; Q49AD1; Q96MQ6;
DE   RecName: Full=Zinc finger protein 90 homolog;
DE            Short=Zfp-90;
DE   AltName: Full=Zinc finger protein 756;
GN   Name=ZFP90; Synonyms=KIAA1954, ZNF756;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
//
ID   ZFP92_HUMAN             Reviewed;         416 AA.
AC   A6NM28;
DE   RecName: Full=Zinc finger protein 92 homolog;
DE            Short=Zfp-92;
GN   Name=ZFP92;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFP91_HUMAN             Reviewed;         570 AA.
AC   Q96JP5; A6NHC4; A8MSG7; Q86V47; Q96JP4; Q96QA3;
DE   RecName: Full=E3 ubiquitin-protein ligase ZFP91;
DE            EC=6.3.2.-;
DE   AltName: Full=Zinc finger protein 757;
DE   AltName: Full=Zinc finger protein 91 homolog;
DE            Short=Zfp-91;
GN   Name=ZFP91; Synonyms=ZNF757; ORFNames=FKSG11;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.
DR   GO; GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
//
ID   ZFPL1_HUMAN             Reviewed;         310 AA.
AC   O95159; A8K7E9; O14616; Q9UID0;
DE   RecName: Full=Zinc finger protein-like 1;
DE   AltName: Full=Zinc finger protein MCG4;
GN   Name=ZFPL1;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
//
ID   ZFR_HUMAN               Reviewed;        1074 AA.
AC   Q96KR1; B2RNR5; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q9H6V4; Q9NTI1;
AC   Q9Y687;
DE   RecName: Full=Zinc finger RNA-binding protein;
DE            Short=hZFR;
DE   AltName: Full=M-phase phosphoprotein homolog;
GN   Name=ZFR;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
//
ID   ZFR2_HUMAN              Reviewed;         939 AA.
AC   Q9UPR6;
DE   RecName: Full=Zinc finger RNA-binding protein 2;
GN   Name=ZFR2; Synonyms=KIAA1086;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFX_HUMAN               Reviewed;         805 AA.
AC   P17010; B9EG97; O43668; Q8WYJ8;
DE   RecName: Full=Zinc finger X-chromosomal protein;
GN   Name=ZFX;
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
DR   GO; GO:0016265; P:death; IEA:Ensembl.
DR   GO; GO:0009790; P:embryo development; IEA:Ensembl.
DR   GO; GO:0009566; P:fertilization; IEA:Ensembl.
DR   GO; GO:0048872; P:homeostasis of number of cells; IEA:Ensembl.
DR   GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
DR   GO; GO:0060746; P:parental behavior; IEA:Ensembl.
DR   GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZFY16_HUMAN             Reviewed;        1539 AA.
AC   Q7Z3T8; O15023; Q5H9U2; Q7LAU7; Q86T69; Q8N5L3; Q8NEK3;
DE   RecName: Full=Zinc finger FYVE domain-containing protein 16;
DE   AltName: Full=Endofin;
DE   AltName: Full=Endosome-associated FYVE domain protein;
GN   Name=ZFYVE16; Synonyms=KIAA0305;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008565; F:protein transporter activity; IMP:UniProtKB.
DR   GO; GO:0030509; P:BMP signaling pathway; TAS:Reactome.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:0006622; P:protein targeting to lysosome; IMP:UniProtKB.
DR   GO; GO:0030100; P:regulation of endocytosis; TAS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; NAS:UniProtKB.
DR   GO; GO:0016050; P:vesicle organization; NAS:UniProtKB.
//
ID   ZFY19_HUMAN             Reviewed;         471 AA.
AC   Q96K21; B3KVB2; C9JNF4; H3BUF9; Q86WC2; Q8WU96;
DE   RecName: Full=Zinc finger FYVE domain-containing protein 19;
DE   AltName: Full=MLL partner containing FYVE domain;
GN   Name=ZFYVE19; Synonyms=MPFYVE;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZFY21_HUMAN             Reviewed;         234 AA.
AC   Q9BQ24; A8K3A4; Q86T05; Q96LT1;
DE   RecName: Full=Zinc finger FYVE domain-containing protein 21;
DE            Short=ZF21;
GN   Name=ZFYVE21;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZFY26_HUMAN             Reviewed;        2539 AA.
AC   Q68DK2; B1B5Y3; B4E2U3; O15035; Q68DT9; Q6AW90; Q6ZR50; Q7Z3A4;
AC   Q7Z3I1; Q8N4W7;
DE   RecName: Full=Zinc finger FYVE domain-containing protein 26;
DE   AltName: Full=FYVE domain-containing centrosomal protein;
DE            Short=FYVE-CENT;
DE   AltName: Full=Spastizin;
GN   Name=ZFYVE26; Synonyms=KIAA0321;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0000910; P:cytokinesis; IMP:UniProtKB.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
//
ID   ZFY27_HUMAN             Reviewed;         411 AA.
AC   Q5T4F4; B7Z3S0; B7Z404; B7Z626; G8JLC3; G8JLF0; J3KP98; Q5T4F1;
AC   Q5T4F2; Q5T4F3; Q8N1K0; Q8N6D6; Q8NCA0; Q8NDE4; Q96M08;
DE   RecName: Full=Protrudin;
DE   AltName: Full=Zinc finger FYVE domain-containing protein 27;
GN   Name=ZFYVE27;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0031175; P:neuron projection development; IDA:UniProtKB.
DR   GO; GO:0048011; P:neurotrophin TRK receptor signaling pathway; ISS:UniProtKB.
DR   GO; GO:0072659; P:protein localization to plasma membrane; ISS:UniProtKB.
//
ID   ZFYV1_HUMAN             Reviewed;         777 AA.
AC   Q9HBF4; Q8WYX7; Q96K57; Q9BXP9; Q9HCI3;
DE   RecName: Full=Zinc finger FYVE domain-containing protein 1;
DE   AltName: Full=Double FYVE-containing protein 1;
DE   AltName: Full=SR3;
DE   AltName: Full=Tandem FYVE fingers-1;
GN   Name=ZFYVE1; Synonyms=DFCP1, KIAA1589, TAFF1, ZNFN2A1;
GN   ORFNames=PP10436;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
//
ID   ZFYV9_HUMAN             Reviewed;        1425 AA.
AC   O95405; Q5T0F6; Q5T0F7; Q9UNE1; Q9Y5R7;
DE   RecName: Full=Zinc finger FYVE domain-containing protein 9;
DE   AltName: Full=Mothers against decapentaplegic homolog-interacting protein;
DE            Short=Madh-interacting protein;
DE   AltName: Full=Novel serine protease;
DE            Short=NSP;
DE   AltName: Full=Receptor activation anchor;
DE            Short=hSARA;
DE   AltName: Full=Smad anchor for receptor activation;
GN   Name=ZFYVE9; Synonyms=MADHIP, SARA, SMADIP;
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB.
DR   GO; GO:0006897; P:endocytosis; NAS:UniProtKB.
DR   GO; GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; TAS:Reactome.
DR   GO; GO:0006508; P:proteolysis; NAS:GOC.
DR   GO; GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.
DR   GO; GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.
DR   GO; GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.
//
ID   ZFY_HUMAN               Reviewed;         801 AA.
AC   P08048; B4DVF7; Q14021; Q15558; Q1RME9; Q24JR0; Q96TF3;
DE   RecName: Full=Zinc finger Y-chromosomal protein;
GN   Name=ZFY;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZG16B_HUMAN             Reviewed;         208 AA.
AC   Q96DA0; A6NIY1; B2R4F6; Q6UW28;
DE   RecName: Full=Zymogen granule protein 16 homolog B;
DE   Flags: Precursor;
GN   Name=ZG16B; ORFNames=UNQ773/PRO1567;
DR   GO; GO:0001895; P:retina homeostasis; IEP:UniProt.
//
ID   ZG16_HUMAN              Reviewed;         167 AA.
AC   O60844; B2R4Z3; B9EK72;
DE   RecName: Full=Zymogen granule membrane protein 16;
DE            Short=Zymogen granule protein 16;
DE            Short=hZG16;
DE   AltName: Full=Secretory lectin ZG16;
DE   Flags: Precursor;
GN   Name=ZG16;
DR   GO; GO:0015031; P:protein transport; TAS:UniProtKB.
//
ID   ZGLP1_HUMAN             Reviewed;         271 AA.
AC   P0C6A0;
DE   RecName: Full=GATA-type zinc finger protein 1;
DE   AltName: Full=GATA-like protein 1;
DE            Short=GLP-1;
GN   Name=ZGLP1; Synonyms=GLP1;
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0048599; P:oocyte development; IEA:Ensembl.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZGPAT_HUMAN             Reviewed;         531 AA.
AC   Q8N5A5; E1P5K1; Q4VXN9; Q5JWI9; Q5JWJ0; Q8NC55; Q8WUV4; Q96JI0;
AC   Q96JU4; Q9H401;
DE   RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein;
DE   AltName: Full=G patch domain-containing protein 6;
DE   AltName: Full=Zinc finger CCCH domain-containing protein 9;
DE   AltName: Full=Zinc finger and G patch domain-containing protein;
GN   Name=ZGPAT; Synonyms=GPATC6, GPATCH6, KIAA1847, ZC3H9, ZC3HDC9, ZIP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZGRF1_HUMAN             Reviewed;        2104 AA.
AC   Q86YA3; B3KQX2; B4DSN6; B4DYU8; E9PDE1; G5EA02; Q6ZU11; Q9NSW3;
AC   Q9NUJ4;
DE   RecName: Full=Protein ZGRF1;
DE   AltName: Full=GRF-type zinc finger domain-containing protein 1;
GN   Name=ZGRF1; Synonyms=C4orf21;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZH11B_HUMAN             Reviewed;         371 AA.
AC   P0C7U3; A6NHR3;
DE   RecName: Full=Probable palmitoyltransferase ZDHHC11B;
DE            EC=2.3.1.225;
DE   AltName: Full=Zinc finger DHHC domain-containing protein 11B;
DE            Short=DHHC-11B;
GN   Name=ZDHHC11B;
DR   GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZHANG_HUMAN             Reviewed;         354 AA.
AC   Q9NS37; B2R8Q9; Q0P5U9; Q52LT3;
DE   RecName: Full=CREB/ATF bZIP transcription factor;
DE   AltName: Full=Host cell factor-binding transcription factor Zhangfei;
DE            Short=HCF-binding transcription factor Zhangfei;
GN   Name=CREBZF; Synonyms=ZF;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045814; P:negative regulation of gene expression, epigenetic; IEP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0009615; P:response to virus; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   ZHX1R_HUMAN             Reviewed;         292 AA.
AC   Q96EF9;
DE   RecName: Full=Zinc fingers and homeoboxes protein 1, isoform 2;
DE   AltName: Full=ZHX1-C8orf76 readthrough transcript protein;
GN   Name=ZHX1-C8orf76; Synonyms=C8orf76;
//
ID   ZHX1_HUMAN              Reviewed;         873 AA.
AC   Q9UKY1; Q8IWD8;
DE   RecName: Full=Zinc fingers and homeoboxes protein 1;
GN   Name=ZHX1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZHX2_HUMAN              Reviewed;         837 AA.
AC   Q9Y6X8;
DE   RecName: Full=Zinc fingers and homeoboxes protein 2;
DE   AltName: Full=Alpha-fetoprotein regulator 1;
DE            Short=AFP regulator 1;
DE   AltName: Full=Regulator of AFP;
DE   AltName: Full=Zinc finger and homeodomain protein 2;
GN   Name=ZHX2; Synonyms=AFR1, KIAA0854, RAF;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0006402; P:mRNA catabolic process; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0035019; P:somatic stem cell maintenance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZHX3_HUMAN              Reviewed;         956 AA.
AC   Q9H4I2; E1P5W5; F5H820; O43145; Q6NUJ7;
DE   RecName: Full=Zinc fingers and homeoboxes protein 3;
DE   AltName: Full=Triple homeobox protein 1;
DE   AltName: Full=Zinc finger and homeodomain protein 3;
GN   Name=ZHX3; Synonyms=KIAA0395, TIX1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZIC1_HUMAN              Reviewed;         447 AA.
AC   Q15915; Q2M3N1;
DE   RecName: Full=Zinc finger protein ZIC 1;
DE   AltName: Full=Zinc finger protein 201;
DE   AltName: Full=Zinc finger protein of the cerebellum 1;
GN   Name=ZIC1; Synonyms=ZIC, ZNF201;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR   GO; GO:0007420; P:brain development; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0042472; P:inner ear morphogenesis; ISS:UniProtKB.
DR   GO; GO:0007389; P:pattern specification process; ISS:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.
DR   GO; GO:0021510; P:spinal cord development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZIC2_HUMAN              Reviewed;         532 AA.
AC   O95409; Q5VYA9; Q9H309;
DE   RecName: Full=Zinc finger protein ZIC 2;
DE   AltName: Full=Zinc finger protein of the cerebellum 2;
GN   Name=ZIC2;
DR   GO; GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; TAS:ProtInc.
DR   GO; GO:0048066; P:developmental pigmentation; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
DR   GO; GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0031290; P:retinal ganglion cell axon guidance; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; ISS:UniProtKB.
//
ID   ZIC3_HUMAN              Reviewed;         467 AA.
AC   O60481; B2CNW4; Q14DE5; Q5JY75;
DE   RecName: Full=Zinc finger protein ZIC 3;
DE   AltName: Full=Zinc finger protein 203;
DE   AltName: Full=Zinc finger protein of the cerebellum 3;
GN   Name=ZIC3; Synonyms=ZNF203;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071907; P:determination of digestive tract left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0035545; P:determination of left/right asymmetry in nervous system; IEA:Ensembl.
DR   GO; GO:0007368; P:determination of left/right symmetry; IMP:BHF-UCL.
DR   GO; GO:0071910; P:determination of liver left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0035469; P:determination of pancreatic left/right asymmetry; IMP:BHF-UCL.
DR   GO; GO:0001947; P:heart looping; IMP:BHF-UCL.
DR   GO; GO:0030324; P:lung development; IMP:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZIC5_HUMAN              Reviewed;         663 AA.
AC   Q96T25; Q5VYB0;
DE   RecName: Full=Zinc finger protein ZIC 5;
DE   AltName: Full=Zinc finger protein of the cerebellum 5;
GN   Name=ZIC5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0030900; P:forebrain development; IEA:Ensembl.
DR   GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
//
ID   ZIC4_HUMAN              Reviewed;         334 AA.
AC   Q8N9L1; A0AVA2; B2RMQ8; B4DF89; B7Z2L2; C9J7D5; J3KQG1; Q4G157;
AC   Q9BZ94;
DE   RecName: Full=Zinc finger protein ZIC 4;
DE   AltName: Full=Zinc finger protein of the cerebellum 4;
GN   Name=ZIC4;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZIK1_HUMAN              Reviewed;         487 AA.
AC   Q3SY52; O43339; Q3SY51; Q3SY53;
DE   RecName: Full=Zinc finger protein interacting with ribonucleoprotein K;
DE   AltName: Full=Zinc finger protein 762;
GN   Name=ZIK1; Synonyms=ZNF762;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZIM2_HUMAN              Reviewed;         527 AA.
AC   Q9NZV7; Q2M3K1;
DE   RecName: Full=Zinc finger imprinted 2;
DE   AltName: Full=Zinc finger protein 656;
GN   Name=ZIM2; Synonyms=ZNF656;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZIM3_HUMAN              Reviewed;         472 AA.
AC   Q96PE6; Q14CA6;
DE   RecName: Full=Zinc finger imprinted 3;
DE   AltName: Full=Zinc finger protein 657;
GN   Name=ZIM3; Synonyms=ZNF657;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZKSC1_HUMAN             Reviewed;         563 AA.
AC   P17029; A4D294; P52745; Q2M1U1; Q8TBW5; Q8TEK7;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;
DE   AltName: Full=Zinc finger protein 139;
DE   AltName: Full=Zinc finger protein 36;
DE   AltName: Full=Zinc finger protein KOX18;
GN   Name=ZKSCAN1; Synonyms=KOX18, ZNF139, ZNF36;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZKSC2_HUMAN             Reviewed;         967 AA.
AC   Q63HK3; A1L3B4; Q6ZN77;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 2;
DE   AltName: Full=Zinc finger protein 694;
GN   Name=ZKSCAN2; Synonyms=ZNF694;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZKSC3_HUMAN             Reviewed;         538 AA.
AC   Q9BRR0; B2R8W2; B3KVC0; H7BXX1; Q5VXH3; Q92972; Q9H4T3;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 3;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 13;
DE   AltName: Full=Zinc finger protein 306;
DE   AltName: Full=Zinc finger protein 309;
DE   AltName: Full=Zinc finger protein 47 homolog;
DE            Short=Zf47;
DE            Short=Zfp-47;
GN   Name=ZKSCAN3; Synonyms=ZFP47, ZNF306, ZNF309, ZSCAN13;
DR   GO; GO:0003682; F:chromatin binding; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0007040; P:lysosome organization; IMP:UniProtKB.
DR   GO; GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.
DR   GO; GO:2000773; P:negative regulation of cellular senescence; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZKSC5_HUMAN             Reviewed;         839 AA.
AC   Q9Y2L8; A4D280; D6W5S9;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 5;
DE   AltName: Full=Zinc finger protein 95 homolog;
DE            Short=Zfp-95;
GN   Name=ZKSCAN5; Synonyms=KIAA1015, ZFP95;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZKSC4_HUMAN             Reviewed;         545 AA.
AC   Q969J2; B2RE32; Q5U7L4;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 4;
DE   AltName: Full=P373c6.1;
DE   AltName: Full=Zinc finger protein 307;
DE   AltName: Full=Zinc finger protein 427;
GN   Name=ZKSCAN4; Synonyms=ZNF307, ZNF427;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZKSC7_HUMAN             Reviewed;         754 AA.
AC   Q9P0L1; A0PJV3; A8K5H0; Q6WL09; Q96FQ2;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 7;
DE   AltName: Full=Zinc finger protein 167;
DE   AltName: Full=Zinc finger protein 448;
DE   AltName: Full=Zinc finger protein 64;
GN   Name=ZKSCAN7; Synonyms=ZNF167, ZNF448, ZNF64;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZKSC8_HUMAN             Reviewed;         578 AA.
AC   Q15776; A1L3D4; Q4VAR1; Q4VAR2; Q4VAR3; Q9H4T1;
DE   RecName: Full=Zinc finger protein with KRAB and SCAN domains 8;
DE   AltName: Full=LD5-1;
DE   AltName: Full=Zinc finger protein 192;
GN   Name=ZKSCAN8; Synonyms=ZNF192;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZMAT1_HUMAN             Reviewed;         638 AA.
AC   Q5H9K5; Q8NDS3; Q96JN6;
DE   RecName: Full=Zinc finger matrin-type protein 1;
GN   Name=ZMAT1; Synonyms=KIAA1789;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZMAT3_HUMAN             Reviewed;         289 AA.
AC   Q9HA38; B3KVA6; D3DNR1; Q96A21;
DE   RecName: Full=Zinc finger matrin-type protein 3;
DE   AltName: Full=Zinc finger protein WIG-1;
DE   AltName: Full=p53-activated gene 608 protein;
GN   Name=ZMAT3; Synonyms=PAG608, WIG1;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
//
ID   ZMAT2_HUMAN             Reviewed;         199 AA.
AC   Q96NC0;
DE   RecName: Full=Zinc finger matrin-type protein 2;
GN   Name=ZMAT2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZMAT4_HUMAN             Reviewed;         229 AA.
AC   Q9H898; Q8WUT8;
DE   RecName: Full=Zinc finger matrin-type protein 4;
GN   Name=ZMAT4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZMAT5_HUMAN             Reviewed;         170 AA.
AC   Q9UDW3; A8K9F6;
DE   RecName: Full=Zinc finger matrin-type protein 5;
DE   AltName: Full=U11/U12 small nuclear ribonucleoprotein 20 kDa protein;
DE            Short=U11/U12 snRNP 20 kDa protein;
DE            Short=U11/U12-20K;
GN   Name=ZMAT5;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IC:HGNC.
//
ID   ZMIZ1_HUMAN             Reviewed;        1067 AA.
AC   Q9ULJ6; Q5JSH9; Q7Z7E6;
DE   RecName: Full=Zinc finger MIZ domain-containing protein 1;
DE   AltName: Full=PIAS-like protein Zimp10;
DE   AltName: Full=Retinoic acid-induced protein 17;
GN   Name=ZMIZ1; Synonyms=KIAA1224, RAI17, ZIMP10;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048844; P:artery morphogenesis; IEA:Ensembl.
DR   GO; GO:0007569; P:cell aging; IEA:Ensembl.
DR   GO; GO:0048589; P:developmental growth; IEA:Ensembl.
DR   GO; GO:0003007; P:heart morphogenesis; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048146; P:positive regulation of fibroblast proliferation; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0001570; P:vasculogenesis; IEA:Ensembl.
DR   GO; GO:0007296; P:vitellogenesis; IEA:Ensembl.
//
ID   ZMIZ2_HUMAN             Reviewed;         920 AA.
AC   Q8NF64; A4D2K7; D3DVL1; O94790; Q0VGB4; Q659A8; Q6JKL5; Q8WTX8;
AC   Q96Q01; Q9BQH7;
DE   RecName: Full=Zinc finger MIZ domain-containing protein 2;
DE   AltName: Full=PIAS-like protein Zimp7;
GN   Name=ZMIZ2; Synonyms=KIAA1886, ZIMP7; ORFNames=HRIHFB2007;
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZMY10_HUMAN             Reviewed;         440 AA.
AC   O75800; A6NK41; B3KU54; O14570; O75801; Q53FE6; Q8N4R6; Q8NDN6;
DE   RecName: Full=Zinc finger MYND domain-containing protein 10;
DE   AltName: Full=Protein BLu;
GN   Name=ZMYND10; Synonyms=BLU; ORFNames=LUCA12.4;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0036159; P:inner dynein arm assembly; IMP:UniProtKB.
DR   GO; GO:0044458; P:motile cilium assembly; IMP:UniProtKB.
DR   GO; GO:0036158; P:outer dynein arm assembly; IMP:UniProtKB.
//
ID   ZMY11_HUMAN             Reviewed;         602 AA.
AC   Q15326; B2R6G8; B7Z293; F6UH50; Q2LD45; Q2LD46; Q2LD47; Q2LD48;
AC   Q5VUI1; Q8N4B3;
DE   RecName: Full=Zinc finger MYND domain-containing protein 11;
DE   AltName: Full=Adenovirus 5 E1A-binding protein;
DE   AltName: Full=Bone morphogenetic protein receptor-associated molecule 1;
DE   AltName: Full=Protein BS69;
GN   Name=ZMYND11; Synonyms=BRAM1, BS69;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0035064; F:methylated histone binding; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; ISS:UniProtKB.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
DR   GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
DR   GO; GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB signaling; IMP:UniProtKB.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0034243; P:regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ZMY15_HUMAN             Reviewed;         742 AA.
AC   Q9H091; B4DXY5; I3L296;
DE   RecName: Full=Zinc finger MYND domain-containing protein 15;
GN   Name=ZMYND15;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0007286; P:spermatid development; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZMY19_HUMAN             Reviewed;         227 AA.
AC   Q96E35; Q5T366;
DE   RecName: Full=Zinc finger MYND domain-containing protein 19;
DE   AltName: Full=Melanin-concentrating hormone receptor 1-interacting zinc finger protein;
DE            Short=MCH-R1-interacting zinc finger protein;
GN   Name=ZMYND19; Synonyms=MIZIP;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZMY12_HUMAN             Reviewed;         365 AA.
AC   Q9H0C1; Q5VUS6; Q8TC87; Q96M51;
DE   RecName: Full=Zinc finger MYND domain-containing protein 12;
GN   Name=ZMYND12;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZMYM1_HUMAN             Reviewed;        1142 AA.
AC   Q5SVZ6; D3DPR7; Q7Z3Q4;
DE   RecName: Full=Zinc finger MYM-type protein 1;
GN   Name=ZMYM1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZMYM2_HUMAN             Reviewed;        1377 AA.
AC   Q9UBW7; A6NDG0; A6NI02; O43212; O43434; O60898; Q5W0Q4; Q5W0T3;
AC   Q63HP0; Q8NE39; Q9H0V5; Q9H538; Q9UEU2;
DE   RecName: Full=Zinc finger MYM-type protein 2;
DE   AltName: Full=Fused in myeloproliferative disorders protein;
DE   AltName: Full=Rearranged in atypical myeloproliferative disorder protein;
DE   AltName: Full=Zinc finger protein 198;
GN   Name=ZMYM2; Synonyms=FIM, RAMP, ZNF198;
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZMYM4_HUMAN             Reviewed;        1548 AA.
AC   Q5VZL5; A0JP19; A0JP20; O43308; Q5T5E1; Q5T5E2; Q7L3Q4;
DE   RecName: Full=Zinc finger MYM-type protein 4;
DE   AltName: Full=Zinc finger protein 262;
GN   Name=ZMYM4; Synonyms=KIAA0425, ZNF262;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   ZMYM5_HUMAN             Reviewed;         669 AA.
AC   Q9UJ78; B2R6V1; Q5T6E1; Q5T6E2; Q5T6E4; Q96IY6; Q9NZY5; Q9UBW0;
AC   Q9UJ77;
DE   RecName: Full=Zinc finger MYM-type protein 5;
DE   AltName: Full=Zinc finger protein 198-like 1;
DE   AltName: Full=Zinc finger protein 237;
GN   Name=ZMYM5; Synonyms=ZNF198L1, ZNF237; ORFNames=HSPC050;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZMYM3_HUMAN             Reviewed;        1370 AA.
AC   Q14202; D3DVV3; O15089; Q96E26;
DE   RecName: Full=Zinc finger MYM-type protein 3;
DE   AltName: Full=Zinc finger protein 261;
GN   Name=ZMYM3; Synonyms=DXS6673E, KIAA0385, ZNF261;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   ZMYM6_HUMAN             Reviewed;        1325 AA.
AC   O95789; B4DRJ6; Q32Q23; Q4G108; Q5SVZ9; Q5SW00; Q69YL4; Q96IY0;
AC   Q9NWF1; Q9P2J4;
DE   RecName: Full=Zinc finger MYM-type protein 6;
DE   AltName: Full=Transposon-derived Buster2 transposase-like protein;
DE   AltName: Full=Zinc finger protein 258;
GN   Name=ZMYM6; Synonyms=Buster2, KIAA1353, ZNF258;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
//
ID   ZMYNB_HUMAN             Reviewed;         154 AA.
AC   Q8NCS4;
DE   RecName: Full=Uncharacterized protein ZMYM6NB;
DE   AltName: Full=ZMYM6 neighbor protein;
DE   Flags: Precursor;
GN   Name=ZMYM6NB;
//
ID   ZN100_HUMAN             Reviewed;         542 AA.
AC   Q8IYN0; Q7M4M0;
DE   RecName: Full=Zinc finger protein 100;
GN   Name=ZNF100;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN101_HUMAN             Reviewed;         436 AA.
AC   Q8IZC7;
DE   RecName: Full=Zinc finger protein 101;
DE   AltName: Full=Zinc finger protein HZF12;
GN   Name=ZNF101;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN106_HUMAN             Reviewed;        1883 AA.
AC   Q9H2Y7; Q6NSD9; Q6PEK1; Q86T43; Q86T45; Q86T50; Q86T58; Q86TA9;
AC   Q96M37; Q9H7B8;
DE   RecName: Full=Zinc finger protein 106;
DE            Short=Zfp-106;
DE   AltName: Full=Zinc finger protein 474;
GN   Name=ZNF106; Synonyms=SH3BP3, ZFP106, ZNF474;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:Ensembl.
//
ID   ZN107_HUMAN             Reviewed;         783 AA.
AC   Q9UII5;
DE   RecName: Full=Zinc finger protein 107;
DE   AltName: Full=Zinc finger protein 588;
DE   AltName: Full=Zinc finger protein ZFD25;
GN   Name=ZNF107; Synonyms=ZFD25, ZNF588;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN112_HUMAN             Reviewed;         913 AA.
AC   Q9UJU3; A4FU53; Q9HCA7;
DE   RecName: Full=Zinc finger protein 112;
DE            Short=Zfp-112;
DE   AltName: Full=Zinc finger protein 228;
GN   Name=ZNF112; Synonyms=ZFP112, ZNF228;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN114_HUMAN             Reviewed;         417 AA.
AC   Q8NC26; A8K6B0; Q08AQ6;
DE   RecName: Full=Zinc finger protein 114;
GN   Name=ZNF114;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN117_HUMAN             Reviewed;         483 AA.
AC   Q03924; Q02313; Q7Z7Q7;
DE   RecName: Full=Zinc finger protein 117;
DE   AltName: Full=Provirus-linked krueppel;
DE            Short=h-PLK;
DE   AltName: Full=Zinc finger protein HPF9;
GN   Name=ZNF117;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN124_HUMAN             Reviewed;         351 AA.
AC   Q15973; B3KNP3; J3KSE1; Q15974; Q4VAJ7; Q5T2V4;
DE   RecName: Full=Zinc finger protein 124;
DE   AltName: Full=Zinc finger protein HZF-16;
GN   Name=ZNF124;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN121_HUMAN             Reviewed;         390 AA.
AC   P58317;
DE   RecName: Full=Zinc finger protein 121;
DE   AltName: Full=Zinc finger protein 20;
GN   Name=ZNF121; Synonyms=ZNF20;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN131_HUMAN             Reviewed;         623 AA.
AC   P52739; B4DRL3; Q6PIF0;
DE   RecName: Full=Zinc finger protein 131;
GN   Name=ZNF131;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN132_HUMAN             Reviewed;         706 AA.
AC   P52740; Q32MI9;
DE   RecName: Full=Zinc finger protein 132;
GN   Name=ZNF132;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN133_HUMAN             Reviewed;         654 AA.
AC   P52736; A8K5S4; Q53XU1; Q5JXV8; Q9BUV2; Q9H443;
DE   RecName: Full=Zinc finger protein 133;
DE   AltName: Full=Zinc finger protein 150;
GN   Name=ZNF133; Synonyms=ZNF150;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN134_HUMAN             Reviewed;         427 AA.
AC   P52741; Q9Y4B2;
DE   RecName: Full=Zinc finger protein 134;
GN   Name=ZNF134;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN135_HUMAN             Reviewed;         658 AA.
AC   P52742; B4DHH9; E9PEV2; F5GYY9; I3L0B3; Q5U5L3; Q8N1I7;
DE   RecName: Full=Zinc finger protein 135;
DE   AltName: Full=Zinc finger protein 61;
DE   AltName: Full=Zinc finger protein 78-like 1;
GN   Name=ZNF135; Synonyms=ZNF61, ZNF78L1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN136_HUMAN             Reviewed;         540 AA.
AC   P52737;
DE   RecName: Full=Zinc finger protein 136;
GN   Name=ZNF136;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZN137_HUMAN             Reviewed;         207 AA.
AC   P52743; Q2TBC7;
DE   RecName: Full=Putative zinc finger protein 137;
DE   AltName: Full=Zinc finger protein 137 pseudogene;
GN   Name=ZNF137P; Synonyms=ZNF137;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN138_HUMAN             Reviewed;         262 AA.
AC   P52744; B4DFX2; B4DP87; E9PHI7; E9PHK7;
DE   RecName: Full=Zinc finger protein 138;
GN   Name=ZNF138;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN140_HUMAN             Reviewed;         457 AA.
AC   P52738; D3DXJ3; Q8IV75;
DE   RecName: Full=Zinc finger protein 140;
GN   Name=ZNF140;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN141_HUMAN             Reviewed;         474 AA.
AC   Q15928; Q6DK07;
DE   RecName: Full=Zinc finger protein 141;
GN   Name=ZNF141; Synonyms=D4S90;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; TAS:ProtInc.
DR   GO; GO:0035108; P:limb morphogenesis; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZN142_HUMAN             Reviewed;        1687 AA.
AC   P52746; Q92510;
DE   RecName: Full=Zinc finger protein 142;
DE   AltName: Full=HA4654;
GN   Name=ZNF142; Synonyms=KIAA0236;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN143_HUMAN             Reviewed;         638 AA.
AC   P52747; A8K518; B4DLY5; O75559; Q8WUK9;
DE   RecName: Full=Zinc finger protein 143;
DE   AltName: Full=SPH-binding factor;
DE   AltName: Full=Selenocysteine tRNA gene transcription-activating factor;
DE            Short=hStaf;
GN   Name=ZNF143; Synonyms=SBF, STAF;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:Reactome.
//
ID   ZN148_HUMAN             Reviewed;         794 AA.
AC   Q9UQR1; D3DN27; O00389; O43591; Q58EY5;
DE   RecName: Full=Zinc finger protein 148;
DE   AltName: Full=Transcription factor ZBP-89;
DE   AltName: Full=Zinc finger DNA-binding protein 89;
GN   Name=ZNF148; Synonyms=ZBP89;
DR   GO; GO:0003690; F:double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0006968; P:cellular defense response; TAS:ProtInc.
DR   GO; GO:0007276; P:gamete generation; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006461; P:protein complex assembly; IEA:Ensembl.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZN154_HUMAN             Reviewed;         437 AA.
AC   Q13106; A7MCY3; Q8IVG7; Q8NAR0;
DE   RecName: Full=Zinc finger protein 154;
GN   Name=ZNF154; Synonyms=KIAA2003;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN157_HUMAN             Reviewed;         506 AA.
AC   P51786; Q96LE9;
DE   RecName: Full=Zinc finger protein 157;
DE   AltName: Full=Zinc finger protein HZF22;
GN   Name=ZNF157;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN155_HUMAN             Reviewed;         538 AA.
AC   Q12901; A2BDE6; B2RB63; B4DM95; J3KQ08; Q6AZZ8; Q9UIE1; Q9UK14;
DE   RecName: Full=Zinc finger protein 155;
GN   Name=ZNF155;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN160_HUMAN             Reviewed;         818 AA.
AC   Q9HCG1; Q14589; Q504Q8; Q96JC5; Q9H7N6;
DE   RecName: Full=Zinc finger protein 160;
DE   AltName: Full=Zinc finger protein HZF5;
DE   AltName: Full=Zinc finger protein Kr18;
DE            Short=HKr18;
GN   Name=ZNF160; Synonyms=KIAA1611;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030097; P:hemopoiesis; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN169_HUMAN             Reviewed;         603 AA.
AC   Q14929; A2AGP5; A8K127; Q6PI28;
DE   RecName: Full=Zinc finger protein 169;
GN   Name=ZNF169;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN174_HUMAN             Reviewed;         407 AA.
AC   Q15697; Q53Y68; Q9BQ34;
DE   RecName: Full=Zinc finger protein 174;
DE   AltName: Full=AW-1;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 8;
GN   Name=ZNF174; Synonyms=ZSCAN8;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN175_HUMAN             Reviewed;         711 AA.
AC   Q9Y473; A8K9H2;
DE   RecName: Full=Zinc finger protein 175;
DE   AltName: Full=Zinc finger protein OTK18;
GN   Name=ZNF175;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN165_HUMAN             Reviewed;         485 AA.
AC   P49910;
DE   RecName: Full=Zinc finger protein 165;
DE   AltName: Full=Cancer/testis antigen 53;
DE            Short=CT53;
DE   AltName: Full=LD65;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 7;
GN   Name=ZNF165; Synonyms=ZPF165, ZSCAN7;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN177_HUMAN             Reviewed;         481 AA.
AC   Q13360; B4DY57; E9PDG0; I3L0I4; Q96ER2;
DE   RecName: Full=Zinc finger protein 177;
GN   Name=ZNF177;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN180_HUMAN             Reviewed;         692 AA.
AC   Q9UJW8; B2RCN6; Q9P1U2;
DE   RecName: Full=Zinc finger protein 180;
DE   AltName: Full=HHZ168;
GN   Name=ZNF180;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN181_HUMAN             Reviewed;         571 AA.
AC   Q2M3W8; B7ZKX3; Q49A75;
DE   RecName: Full=Zinc finger protein 181;
DE   AltName: Full=HHZ181;
GN   Name=ZNF181;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN182_HUMAN             Reviewed;         639 AA.
AC   P17025; A2IDD7; Q3KP67; Q96QH7;
DE   RecName: Full=Zinc finger protein 182;
DE   AltName: Full=Zinc finger protein 21;
DE   AltName: Full=Zinc finger protein KOX14;
GN   Name=ZNF182; Synonyms=KOX14, ZNF21;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN184_HUMAN             Reviewed;         751 AA.
AC   Q99676; B2R715; O60792; Q8TBA9;
DE   RecName: Full=Zinc finger protein 184;
GN   Name=ZNF184;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN189_HUMAN             Reviewed;         626 AA.
AC   O75820; O75802; Q5T7D7; Q5T7D8; Q5T7D9; Q9UBL4; Q9UPE9; Q9UPF0;
AC   Q9UPF1;
DE   RecName: Full=Zinc finger protein 189;
GN   Name=ZNF189;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN185_HUMAN             Reviewed;         689 AA.
AC   O15231; A4FTV3; A6NME5; B4DLE9; B7Z771; B8K2L9; B8K2M0; B8K2M1;
AC   B8K2M2; E9PFR6; F5GXF7; F5GZL4; F8W8V7; H0Y4M8; O00345; Q8N1R8;
AC   Q9NSD2;
DE   RecName: Full=Zinc finger protein 185;
DE   AltName: Full=LIM domain protein ZNF185;
DE   AltName: Full=P1-A;
GN   Name=ZNF185;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZN195_HUMAN             Reviewed;         629 AA.
AC   O14628; A8K234; B3KTK2; B4DEL0; C9JLY9; L7MNK2; Q0VAJ6; Q658N8;
AC   Q6ZNA9;
DE   RecName: Full=Zinc finger protein 195;
GN   Name=ZNF195; Synonyms=ZNFP104;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN202_HUMAN             Reviewed;         648 AA.
AC   O95125; B0LPH9; Q4JG21; Q9H1B9; Q9NSM4;
DE   RecName: Full=Zinc finger protein 202;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 10;
GN   Name=ZNF202; Synonyms=ZKSCAN10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0006629; P:lipid metabolic process; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
//
ID   ZN197_HUMAN             Reviewed;        1029 AA.
AC   O14709; B2RAH8; Q86VG0;
DE   RecName: Full=Zinc finger protein 197;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 9;
DE   AltName: Full=ZnF20;
DE   AltName: Full=pVHL-associated KRAB domain-containing protein;
GN   Name=ZNF197; Synonyms=ZKSCAN9, ZNF166;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN205_HUMAN             Reviewed;         554 AA.
AC   O95201; A8MZK0; D3DUB4; Q9BU95;
DE   RecName: Full=Zinc finger protein 205;
DE   AltName: Full=Zinc finger protein 210;
GN   Name=ZNF205; Synonyms=ZNF210;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
DR   GO; GO:0010729; P:positive regulation of hydrogen peroxide biosynthetic process; IMP:BHF-UCL.
DR   GO; GO:1901030; P:positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; IMP:BHF-UCL.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN200_HUMAN             Reviewed;         395 AA.
AC   P98182; D3DUB7; D3DUB8; O15361; Q5XKM5; Q7Z5V1;
DE   RecName: Full=Zinc finger protein 200;
GN   Name=ZNF200; Synonyms=ZNFMF;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN207_HUMAN             Reviewed;         478 AA.
AC   O43670; A8K6Y6; E1P660; E1P661; E1P662; Q53XS9; Q96HW5; Q9BUQ7;
DE   RecName: Full=BUB3-interacting and GLEBS motif-containing protein ZNF207;
DE            Short=BuGZ;
DE   AltName: Full=Zinc finger protein 207;
GN   Name=ZNF207; Synonyms=BUGZ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008201; F:heparin binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
DR   GO; GO:0051983; P:regulation of chromosome segregation; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
//
ID   ZN208_HUMAN             Reviewed;        1280 AA.
AC   O43345;
DE   RecName: Full=Zinc finger protein 208;
DE   AltName: Full=Zinc finger protein 91-like;
GN   Name=ZNF208; Synonyms=ZNF91L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN211_HUMAN             Reviewed;         564 AA.
AC   Q13398; B4DH10; B4DLC9; B4E3C9; B9ZVS7; B9ZVW1; F8WDV2; Q05BQ7;
AC   Q2TAL7; Q59EG4; Q59G36; Q5EBL6;
DE   RecName: Full=Zinc finger protein 211;
DE   AltName: Full=Zinc finger protein C2H2-25;
GN   Name=ZNF211;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN212_HUMAN             Reviewed;         495 AA.
AC   Q9UDV6; B2RCF4; Q13396; Q8N664;
DE   RecName: Full=Zinc finger protein 212;
DE   AltName: Full=Zinc finger protein C2H2-150;
GN   Name=ZNF212; Synonyms=ZNFC150;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN213_HUMAN             Reviewed;         459 AA.
AC   O14771; A8K1B9; Q96IS1;
DE   RecName: Full=Zinc finger protein 213;
DE   AltName: Full=Putative transcription factor CR53;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 21;
GN   Name=ZNF213; Synonyms=ZKSCAN21;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN214_HUMAN             Reviewed;         606 AA.
AC   Q9UL59; B2R8Q1;
DE   RecName: Full=Zinc finger protein 214;
DE   AltName: Full=BWSCR2-associated zinc finger protein 1;
DE            Short=BAZ-1;
GN   Name=ZNF214; Synonyms=BAZ1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN215_HUMAN             Reviewed;         517 AA.
AC   Q9UL58; Q96C84;
DE   RecName: Full=Zinc finger protein 215;
DE   AltName: Full=BWSCR2-associated zinc finger protein 2;
DE            Short=BAZ-2;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 11;
GN   Name=ZNF215; Synonyms=BAZ2, ZKSCAN11;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN217_HUMAN             Reviewed;        1048 AA.
AC   O75362; E1P5Y6; Q14DB8;
DE   RecName: Full=Zinc finger protein 217;
GN   Name=ZNF217; Synonyms=ZABC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; TAS:ProtInc.
//
ID   ZN219_HUMAN             Reviewed;         722 AA.
AC   Q9P2Y4; D3DS16; Q53Y57; Q8IYC1; Q9BW28;
DE   RecName: Full=Zinc finger protein 219;
GN   Name=ZNF219;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0004969; F:histamine receptor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0001505; P:regulation of neurotransmitter levels; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IDA:UniProtKB.
//
ID   ZN221_HUMAN             Reviewed;         617 AA.
AC   Q9UK13; B2RAI6; Q2M2H2; Q9P1U8;
DE   RecName: Full=Zinc finger protein 221;
GN   Name=ZNF221;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN222_HUMAN             Reviewed;         451 AA.
AC   Q9UK12; G5E9B9; Q8N6G7; Q9P1U5;
DE   RecName: Full=Zinc finger protein 222;
GN   Name=ZNF222;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN223_HUMAN             Reviewed;         482 AA.
AC   Q9UK11; Q15736; Q8TBJ3; Q9HCA9;
DE   RecName: Full=Zinc finger protein 223;
GN   Name=ZNF223;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN224_HUMAN             Reviewed;         707 AA.
AC   Q9NZL3; A6NFW9; P17033; Q86V10; Q8IZC8; Q9UID9; Q9Y2P6;
DE   RecName: Full=Zinc finger protein 224;
DE   AltName: Full=Bone marrow zinc finger 2;
DE            Short=BMZF-2;
DE   AltName: Full=Zinc finger protein 233;
DE   AltName: Full=Zinc finger protein 255;
DE   AltName: Full=Zinc finger protein 27;
DE   AltName: Full=Zinc finger protein KOX22;
GN   Name=ZNF224; Synonyms=BMZF2, KOX22, ZNF233, ZNF255, ZNF27;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN225_HUMAN             Reviewed;         706 AA.
AC   Q9UK10; A8K8S2; Q53F12; Q9NS46; Q9UID8;
DE   RecName: Full=Zinc finger protein 225;
GN   Name=ZNF225;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN226_HUMAN             Reviewed;         803 AA.
AC   Q9NYT6; Q8WWE6; Q96TE6; Q9NS44;
DE   RecName: Full=Zinc finger protein 226;
GN   Name=ZNF226;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN227_HUMAN             Reviewed;         799 AA.
AC   Q86WZ6; B3KRU7;
DE   RecName: Full=Zinc finger protein 227;
GN   Name=ZNF227;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN229_HUMAN             Reviewed;         825 AA.
AC   Q9UJW7; B2RWN3; Q59FV2; Q86WL9;
DE   RecName: Full=Zinc finger protein 229;
GN   Name=ZNF229;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN230_HUMAN             Reviewed;         474 AA.
AC   Q9UIE0; O15322; Q504X7; Q86W84; Q9P1U6;
DE   RecName: Full=Zinc finger protein 230;
DE   AltName: Full=Zinc finger protein FDZF2;
GN   Name=ZNF230; Synonyms=FDZF2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN232_HUMAN             Reviewed;         417 AA.
AC   Q9UNY5;
DE   RecName: Full=Zinc finger protein 232;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 11;
GN   Name=ZNF232; Synonyms=ZSCAN11;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN234_HUMAN             Reviewed;         700 AA.
AC   Q14588; A8K1C8; Q96IR4; Q9NS45; Q9NYT7;
DE   RecName: Full=Zinc finger protein 234;
DE   AltName: Full=Zinc finger protein 269;
DE   AltName: Full=Zinc finger protein HZF4;
GN   Name=ZNF234; Synonyms=ZNF269;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN233_HUMAN             Reviewed;         670 AA.
AC   A6NK53; B2RN78; B2RN79; Q86WL8;
DE   RecName: Full=Zinc finger protein 233;
GN   Name=ZNF233;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN235_HUMAN             Reviewed;         738 AA.
AC   Q14590; B4DTQ7; O14898; O14899; Q17RR8;
DE   RecName: Full=Zinc finger protein 235;
DE   AltName: Full=Zinc finger protein 270;
DE   AltName: Full=Zinc finger protein 93 homolog;
DE            Short=Zfp-93;
DE   AltName: Full=Zinc finger protein HZF6;
GN   Name=ZNF235; Synonyms=ZFP93, ZNF270;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN236_HUMAN             Reviewed;        1845 AA.
AC   Q9UL36; B2RTX9; Q9UL37;
DE   RecName: Full=Zinc finger protein 236;
GN   Name=ZNF236;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN239_HUMAN             Reviewed;         458 AA.
AC   Q16600; Q5T1G9; Q8TAS5;
DE   RecName: Full=Zinc finger protein 239;
DE   AltName: Full=Zinc finger protein HOK-2;
DE   AltName: Full=Zinc finger protein MOK-2;
GN   Name=ZNF239; Synonyms=HOK2, MOK2;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN248_HUMAN             Reviewed;         579 AA.
AC   Q8NDW4; Q8NDV8; Q9UMP3;
DE   RecName: Full=Zinc finger protein 248;
GN   Name=ZNF248;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN250_HUMAN             Reviewed;         560 AA.
AC   P15622; D3DWP1; Q59HE9; Q8N942; Q96AH9;
DE   RecName: Full=Zinc finger protein 250;
DE   AltName: Full=Zinc finger protein 647;
GN   Name=ZNF250; Synonyms=ZNF647;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN251_HUMAN             Reviewed;         671 AA.
AC   Q9BRH9; Q2M219;
DE   RecName: Full=Zinc finger protein 251;
GN   Name=ZNF251;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN253_HUMAN             Reviewed;         499 AA.
AC   O75346; A4FVA7; Q0P6G3; Q6P0L2; Q8NCA3; Q8NCF9;
DE   RecName: Full=Zinc finger protein 253;
DE   AltName: Full=Bone marrow zinc finger 1;
DE            Short=BMZF-1;
DE   AltName: Full=Zinc finger protein 411;
GN   Name=ZNF253; Synonyms=BMZF1, ZNF411;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN254_HUMAN             Reviewed;         659 AA.
AC   O75437; A4QPC0; Q86XL7;
DE   RecName: Full=Zinc finger protein 254;
DE   AltName: Full=Bone marrow zinc finger 5;
DE            Short=BMZF-5;
DE   AltName: Full=Hematopoietic cell-derived zinc finger protein 1;
DE            Short=HD-ZNF1;
DE   AltName: Full=Zinc finger protein 539;
DE   AltName: Full=Zinc finger protein 91-like;
GN   Name=ZNF254; Synonyms=BMZF5, ZNF539, ZNF91L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN256_HUMAN             Reviewed;         627 AA.
AC   Q9Y2P7; B2RA92; Q53Y85; Q9BV71;
DE   RecName: Full=Zinc finger protein 256;
DE   AltName: Full=Bone marrow zinc finger 3;
DE            Short=BMZF-3;
GN   Name=ZNF256; Synonyms=BMZF3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN257_HUMAN             Reviewed;         563 AA.
AC   Q9Y2Q1; B3KPS4; E9PG34; Q8NE34;
DE   RecName: Full=Zinc finger protein 257;
DE   AltName: Full=Bone marrow zinc finger 4;
DE            Short=BMZF-4;
GN   Name=ZNF257; Synonyms=BMZF4;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN260_HUMAN             Reviewed;         412 AA.
AC   Q3ZCT1; Q0VF43;
DE   RecName: Full=Zinc finger protein 260;
DE            Short=Zfp-260;
GN   Name=ZNF260; Synonyms=ZFP260;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN263_HUMAN             Reviewed;         683 AA.
AC   O14978; B2R634; O43387; Q96H95;
DE   RecName: Full=Zinc finger protein 263;
DE   AltName: Full=Zinc finger protein FPM315;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 12;
GN   Name=ZNF263; Synonyms=FPM315, ZKSCAN12;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN264_HUMAN             Reviewed;         627 AA.
AC   O43296; A8K8Y9; Q9P1V0;
DE   RecName: Full=Zinc finger protein 264;
GN   Name=ZNF264; Synonyms=KIAA0412;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN266_HUMAN             Reviewed;         549 AA.
AC   Q14584; A0AV90; A4FU85; Q6IQ07; Q6U8A5; Q8IVG3; Q8WVX1; Q96SX9;
DE   RecName: Full=Zinc finger protein 266;
DE   AltName: Full=Zinc finger protein HZF1;
GN   Name=ZNF266; Synonyms=KIAA2007;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN267_HUMAN             Reviewed;         743 AA.
AC   Q14586; A0JNZ9; Q8NE41; Q9NRJ0;
DE   RecName: Full=Zinc finger protein 267;
DE   AltName: Full=Zinc finger protein HZF2;
GN   Name=ZNF267;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN268_HUMAN             Reviewed;         947 AA.
AC   Q14587; Q8TDG8; Q96RH4; Q9BZJ9;
DE   RecName: Full=Zinc finger protein 268;
DE   AltName: Full=Zinc finger protein HZF3;
GN   Name=ZNF268;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0071356; P:cellular response to tumor necrosis factor; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0071157; P:negative regulation of cell cycle arrest; IMP:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.
DR   GO; GO:0045597; P:positive regulation of cell differentiation; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.
DR   GO; GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0090073; P:positive regulation of protein homodimerization activity; IDA:UniProtKB.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IDA:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0046022; P:positive regulation of transcription from RNA polymerase II promoter during mitosis; IMP:UniProtKB.
DR   GO; GO:0007346; P:regulation of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:0043497; P:regulation of protein heterodimerization activity; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN271_HUMAN             Reviewed;         655 AA.
AC   Q14591; B3KN34; Q96T29; Q9BSX2; Q9UN33; Q9Y5B7;
DE   RecName: Full=Zinc finger protein 271;
DE   AltName: Full=CT-ZFP48;
DE   AltName: Full=Epstein-Barr virus-induced zinc finger protein;
DE            Short=EBV-induced zinc finger protein;
DE            Short=ZNF-EB;
DE   AltName: Full=Zinc finger protein HZF7;
DE   AltName: Full=Zinc finger protein ZNFphex133;
DE   AltName: Full=Zinc finger protein dp;
DE            Short=ZNF-dp;
GN   Name=ZNF271; Synonyms=ZNFEB;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN273_HUMAN             Reviewed;         569 AA.
AC   Q14593; B3KQZ5; Q6P3V4;
DE   RecName: Full=Zinc finger protein 273;
DE   AltName: Full=Zinc finger protein HZF9;
GN   Name=ZNF273;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN274_HUMAN             Reviewed;         653 AA.
AC   Q96GC6; Q53XU4; Q6MZG1; Q8WY37; Q8WY38; Q92969; Q9UII0; Q9UII1;
DE   RecName: Full=Neurotrophin receptor-interacting factor homolog;
DE   AltName: Full=Zinc finger protein 274;
DE   AltName: Full=Zinc finger protein HFB101;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 19;
DE   AltName: Full=Zinc finger protein zfp2;
DE            Short=Zf2;
GN   Name=ZNF274; Synonyms=ZKSCAN19; ORFNames=SP2114;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN275_HUMAN             Reviewed;         429 AA.
AC   Q9NSD4;
DE   RecName: Full=Zinc finger protein 275;
GN   Name=ZNF275;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN277_HUMAN             Reviewed;         450 AA.
AC   Q9NRM2; Q75MZ2; Q75MZ3; Q8WY14;
DE   RecName: Full=Zinc finger protein 277;
DE   AltName: Full=Nuclear receptor-interacting factor 4;
GN   Name=ZNF277; Synonyms=NRIF4, ZNF277P;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN281_HUMAN             Reviewed;         895 AA.
AC   Q9Y2X9; A6NF48; B3KMX2; Q5RKW5; Q9NY92;
DE   RecName: Full=Zinc finger protein 281;
DE   AltName: Full=GC-box-binding zinc finger protein 1;
DE   AltName: Full=Transcription factor ZBP-99;
DE   AltName: Full=Zinc finger DNA-binding protein 99;
GN   Name=ZNF281; Synonyms=GZP1, ZBP99;
DR   GO; GO:0001047; F:core promoter binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0010172; P:embryonic body morphogenesis; ISS:UniProtKB.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0048863; P:stem cell differentiation; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN282_HUMAN             Reviewed;         671 AA.
AC   Q9UDV7; O43691; Q6DKK0;
DE   RecName: Full=Zinc finger protein 282;
DE   AltName: Full=HTLV-I U5RE-binding protein 1;
DE            Short=HUB-1;
GN   Name=ZNF282; Synonyms=HUB1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN276_HUMAN             Reviewed;         614 AA.
AC   Q8N554; Q0VGA1; Q2TBE8; Q3B7H7;
DE   RecName: Full=Zinc finger protein 276;
DE            Short=Zfp-276;
DE   AltName: Full=Zinc finger protein 477;
GN   Name=ZNF276; Synonyms=ZFP276, ZNF477;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN283_HUMAN             Reviewed;         679 AA.
AC   Q8N7M2; B4DGZ5; B7WP04; Q6RFR9; Q86WM6;
DE   RecName: Full=Zinc finger protein 283;
DE   AltName: Full=Zinc finger protein HZF19;
GN   Name=ZNF283;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN287_HUMAN             Reviewed;         754 AA.
AC   Q9HBT7; Q6IAG1;
DE   RecName: Full=Zinc finger protein 287;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 13;
GN   Name=ZNF287; Synonyms=ZKSCAN13;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0042035; P:regulation of cytokine biosynthetic process; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN285_HUMAN             Reviewed;         590 AA.
AC   Q96NJ3; Q17RJ3; Q6B0A8; Q6ISR5;
DE   RecName: Full=Zinc finger protein 285;
DE   AltName: Full=Zinc finger protein 285A;
GN   Name=ZNF285; Synonyms=ZNF285A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN284_HUMAN             Reviewed;         593 AA.
AC   Q2VY69; Q86WM1;
DE   RecName: Full=Zinc finger protein 284;
GN   Name=ZNF284; Synonyms=ZNF284L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN292_HUMAN             Reviewed;        2723 AA.
AC   O60281; Q5W0B2; Q7Z3L7; Q9H8G3; Q9H8J4;
DE   RecName: Full=Zinc finger protein 292;
GN   Name=ZNF292; Synonyms=KIAA0530;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IEA:Ensembl.
//
ID   ZN300_HUMAN             Reviewed;         604 AA.
AC   Q96RE9; A8MY91; B3KU35; B4DU78; F5GWS1; Q06DQ3; Q17RP3; Q5H9N5;
DE   RecName: Full=Zinc finger protein 300;
GN   Name=ZNF300;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN296_HUMAN             Reviewed;         475 AA.
AC   Q8WUU4;
DE   RecName: Full=Zinc finger protein 296;
DE            Short=ZFP296;
DE   AltName: Full=Zinc finger protein 342;
GN   Name=ZNF296; Synonyms=ZNF342;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN302_HUMAN             Reviewed;         478 AA.
AC   Q9NR11; Q658J3; Q9BZD8; Q9P0J4;
DE   RecName: Full=Zinc finger protein 302;
DE   AltName: Full=Zinc finger protein 135-like;
DE   AltName: Full=Zinc finger protein 140-like;
DE   AltName: Full=Zinc finger protein 327;
GN   Name=ZNF302; Synonyms=ZNF135L, ZNF140L, ZNF327;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN304_HUMAN             Reviewed;         659 AA.
AC   Q9HCX3;
DE   RecName: Full=Zinc finger protein 304;
GN   Name=ZNF304;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN311_HUMAN             Reviewed;         666 AA.
AC   Q5JNZ3; A2BFK5; B0S7Y4; Q92971;
DE   RecName: Full=Zinc finger protein 311;
DE   AltName: Full=Zinc finger protein zfp-31;
GN   Name=ZNF311; Synonyms=ZFP31;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN316_HUMAN             Reviewed;        1004 AA.
AC   A6NFI3;
DE   RecName: Full=Zinc finger protein 316;
GN   Name=ZNF316;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN317_HUMAN             Reviewed;         595 AA.
AC   Q96PQ6; Q6DCA9; Q96PM0; Q96PM1; Q96PT2; Q9HCI4;
DE   RecName: Full=Zinc finger protein 317;
GN   Name=ZNF317; Synonyms=KIAA1588;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN318_HUMAN             Reviewed;        2279 AA.
AC   Q5VUA4; O94796; Q4G0E4; Q8NEM6; Q9UNU8; Q9Y2W9;
DE   RecName: Full=Zinc finger protein 318;
DE   AltName: Full=Endocrine regulatory protein;
GN   Name=ZNF318; ORFNames=HRIHFB2436;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN319_HUMAN             Reviewed;         582 AA.
AC   Q9P2F9; Q52LH8;
DE   RecName: Full=Zinc finger protein 319;
GN   Name=ZNF319; Synonyms=KIAA1388;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN320_HUMAN             Reviewed;         509 AA.
AC   A2RRD8; Q8NDR6;
DE   RecName: Full=Zinc finger protein 320;
GN   Name=ZNF320;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN322_HUMAN             Reviewed;         402 AA.
AC   Q6U7Q0; A8K1X3; Q0VDH6; Q6B0G2; Q86W72; Q9H5I9;
DE   RecName: Full=Zinc finger protein 322;
DE   AltName: Full=Zinc finger protein 322A;
DE   AltName: Full=Zinc finger protein 388;
DE   AltName: Full=Zinc finger protein 489;
GN   Name=ZNF322; Synonyms=ZNF322A, ZNF388, ZNF489;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN321_HUMAN             Reviewed;         164 AA.
AC   Q8N8H1; B7ZB38; Q68DZ0; Q86SS5;
DE   RecName: Full=Putative protein ZNF321;
DE   AltName: Full=Zinc finger protein 321 pseudogene;
GN   Name=ZNF321P; Synonyms=ZNF321;
//
ID   ZN326_HUMAN             Reviewed;         582 AA.
AC   Q5BKZ1; A8MYX1; B4DLN0; B4E179; Q5VW93; Q5VW94; Q5VW96; Q5VW97;
AC   Q6NSA2; Q7Z638; Q7Z6C2;
DE   RecName: Full=DBIRD complex subunit ZNF326;
DE   AltName: Full=Zinc finger protein 326;
DE   AltName: Full=Zinc finger protein interacting with mRNPs and DBC1;
GN   Name=ZNF326; Synonyms=ZIRD;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000993; F:RNA polymerase II core binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0032784; P:regulation of DNA-templated transcription, elongation; IMP:UniProtKB.
DR   GO; GO:0008380; P:RNA splicing; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN329_HUMAN             Reviewed;         541 AA.
AC   Q86UD4; B3KR32; Q9H9R7;
DE   RecName: Full=Zinc finger protein 329;
GN   Name=ZNF329;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN330_HUMAN             Reviewed;         320 AA.
AC   Q9Y3S2; B2RDA3;
DE   RecName: Full=Zinc finger protein 330;
DE   AltName: Full=Nucleolar autoantigen 36;
DE   AltName: Full=Nucleolar cysteine-rich protein;
GN   Name=ZNF330; Synonyms=NOA36;
DR   GO; GO:0046872; F:metal ion binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZN331_HUMAN             Reviewed;         463 AA.
AC   Q9NQX6; Q96GJ4;
DE   RecName: Full=Zinc finger protein 331;
DE   AltName: Full=C2H2-like zinc finger protein rearranged in thyroid adenomas;
DE   AltName: Full=Zinc finger protein 361;
DE   AltName: Full=Zinc finger protein 463;
GN   Name=ZNF331; Synonyms=RITA, ZNF361, ZNF463;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN334_HUMAN             Reviewed;         680 AA.
AC   Q9HCZ1; Q5T6U2; Q9NVW4;
DE   RecName: Full=Zinc finger protein 334;
GN   Name=ZNF334;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN333_HUMAN             Reviewed;         665 AA.
AC   Q96JL9; Q8TDL0;
DE   RecName: Full=Zinc finger protein 333;
GN   Name=ZNF333; Synonyms=KIAA1806;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN335_HUMAN             Reviewed;        1342 AA.
AC   Q9H4Z2; B4DLG7; Q548D0; Q9H684;
DE   RecName: Full=Zinc finger protein 335;
DE   AltName: Full=NRC-interacting factor 1;
DE            Short=NIF-1;
GN   Name=ZNF335;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
DR   GO; GO:0007420; P:brain development; IMP:UniProtKB.
DR   GO; GO:0048854; P:brain morphogenesis; IEA:Ensembl.
DR   GO; GO:0021895; P:cerebral cortex neuron differentiation; IEA:Ensembl.
DR   GO; GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0048812; P:neuron projection morphogenesis; ISS:UniProtKB.
DR   GO; GO:0050671; P:positive regulation of lymphocyte proliferation; IMP:UniProtKB.
DR   GO; GO:0002052; P:positive regulation of neuroblast proliferation; ISS:UniProtKB.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IMP:UniProtKB.
DR   GO; GO:0040029; P:regulation of gene expression, epigenetic; IMP:UniProtKB.
DR   GO; GO:0051569; P:regulation of histone H3-K4 methylation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN33A_HUMAN             Reviewed;         810 AA.
AC   Q06730; A8K9X9; F8WAJ5; P17013; Q5VZ86;
DE   RecName: Full=Zinc finger protein 33A;
DE   AltName: Full=Zinc finger and ZAK-associated protein with KRAB domain;
DE            Short=ZZaPK;
DE   AltName: Full=Zinc finger protein 11A;
DE   AltName: Full=Zinc finger protein KOX31;
GN   Name=ZNF33A; Synonyms=KIAA0065, KOX31, ZNF11, ZNF11A, ZNF33;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN337_HUMAN             Reviewed;         751 AA.
AC   Q9Y3M9; Q9Y3Y5;
DE   RecName: Full=Zinc finger protein 337;
GN   Name=ZNF337;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN33B_HUMAN             Reviewed;         778 AA.
AC   Q06732; Q06731; Q32MA2; Q86XY8; Q8NDW3;
DE   RecName: Full=Zinc finger protein 33B;
DE   AltName: Full=Zinc finger protein 11B;
DE   AltName: Full=Zinc finger protein KOX2;
GN   Name=ZNF33B; Synonyms=KOX2, ZNF11B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN343_HUMAN             Reviewed;         599 AA.
AC   Q6P1L6; Q5JXU8; Q5JXU9; Q8N8F2; Q96EX8; Q96NA5; Q9BQB0;
DE   RecName: Full=Zinc finger protein 343;
GN   Name=ZNF343;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN341_HUMAN             Reviewed;         854 AA.
AC   Q9BYN7; A2RUF4; B2RXE5; B7ZM09; Q5JXM8; Q96ST5;
DE   RecName: Full=Zinc finger protein 341;
GN   Name=ZNF341;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN346_HUMAN             Reviewed;         294 AA.
AC   Q9UL40; Q68CV9; Q6ZMW1;
DE   RecName: Full=Zinc finger protein 346;
DE   AltName: Full=Just another zinc finger protein;
GN   Name=ZNF346; Synonyms=JAZ;
DR   GO; GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
//
ID   ZN345_HUMAN             Reviewed;         488 AA.
AC   Q14585;
DE   RecName: Full=Zinc finger protein 345;
DE   AltName: Full=Zinc finger protein HZF10;
GN   Name=ZNF345;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:ProtInc.
//
ID   ZN347_HUMAN             Reviewed;         839 AA.
AC   Q96SE7; B3KU77; B9EG59; G5E9N4; Q8TCN1;
DE   RecName: Full=Zinc finger protein 347;
DE   AltName: Full=Zinc finger protein 1111;
GN   Name=ZNF347; Synonyms=ZNF1111;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN362_HUMAN             Reviewed;         420 AA.
AC   Q5T0B9; Q8WYU4;
DE   RecName: Full=Zinc finger protein 362;
GN   Name=ZNF362; ORFNames=PP6997;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN350_HUMAN             Reviewed;         532 AA.
AC   Q9GZX5; Q96G73; Q9HAQ4;
DE   RecName: Full=Zinc finger protein 350;
DE   AltName: Full=KRAB zinc finger protein ZFQR;
DE   AltName: Full=Zinc finger and BRCA1-interacting protein with a KRAB domain 1;
DE   AltName: Full=Zinc finger protein ZBRK1;
GN   Name=ZNF350; Synonyms=ZBRK1;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN358_HUMAN             Reviewed;         568 AA.
AC   Q9NW07; Q9BTM7;
DE   RecName: Full=Zinc finger protein 358;
GN   Name=ZNF358;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0035115; P:embryonic forelimb morphogenesis; ISS:UniProtKB.
DR   GO; GO:0021915; P:neural tube development; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN363_HUMAN             Reviewed;         261 AA.
AC   Q96PM5; B3KRG3; C7E541; C7E542; C7E543; D3YRV2; E7EMC8; E7ETW5;
AC   J3KPI0; Q2KN33; Q59GN7; Q86X26; Q96PR5;
DE   RecName: Full=RING finger and CHY zinc finger domain-containing protein 1;
DE            EC=6.3.2.-;
DE   AltName: Full=Androgen receptor N-terminal-interacting protein;
DE   AltName: Full=CH-rich-interacting match with PLAG1;
DE   AltName: Full=E3 ubiquitin-protein ligase Pirh2;
DE   AltName: Full=RING finger protein 199;
DE   AltName: Full=Zinc finger protein 363;
DE   AltName: Full=p53-induced RING-H2 protein;
DE            Short=hPirh2;
GN   Name=RCHY1; Synonyms=ARNIP, CHIMP, PIRH2, RNF199, ZNF363;
DR   GO; GO:0002039; F:p53 binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IDA:UniProtKB.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
//
ID   ZN365_HUMAN             Reviewed;         407 AA.
AC   Q70YC5; A8K0F0; O94930; Q05D75; Q5HYE6; Q68SG8; Q6NSK2; Q6P9D4;
AC   Q70YC6; Q70YC7;
DE   RecName: Full=Protein ZNF365;
DE   AltName: Full=Protein su48;
GN   Name=ZNF365; Synonyms=KIAA0844;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
//
ID   ZN366_HUMAN             Reviewed;         744 AA.
AC   Q8N895; Q5HYI9; Q7RTV4;
DE   RecName: Full=Zinc finger protein 366;
GN   Name=ZNF366;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
DR   GO; GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
DR   GO; GO:0043627; P:response to estrogen; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN367_HUMAN             Reviewed;         350 AA.
AC   Q7RTV3; Q6Q7C8;
DE   RecName: Full=Zinc finger protein 367;
DE   AltName: Full=C2H2 zinc finger protein ZFF29;
GN   Name=ZNF367; Synonyms=ZFF29;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN382_HUMAN             Reviewed;         550 AA.
AC   Q96SR6; A3KMP6; A8MT55; C9K0V5; Q53ZY8; Q5JPJ2;
DE   RecName: Full=Zinc finger protein 382;
DE   AltName: Full=KRAB/zinc finger suppressor protein 1;
DE            Short=KS1;
DE   AltName: Full=Multiple zinc finger and krueppel-associated box protein KS1;
GN   Name=ZNF382;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN37A_HUMAN             Reviewed;         561 AA.
AC   P17032; B3KRQ3; D3DRZ3; Q96B88;
DE   RecName: Full=Zinc finger protein 37A;
DE   AltName: Full=Zinc finger protein KOX21;
GN   Name=ZNF37A; Synonyms=KOX21, ZNF37;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN383_HUMAN             Reviewed;         475 AA.
AC   Q8NA42; Q6X2C7;
DE   RecName: Full=Zinc finger protein 383;
GN   Name=ZNF383; ORFNames=HSD17;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN384_HUMAN             Reviewed;         577 AA.
AC   Q8TF68; O15407; Q7Z722; Q8N938;
DE   RecName: Full=Zinc finger protein 384;
DE   AltName: Full=CAG repeat protein 1;
DE   AltName: Full=CAS-interacting zinc finger protein;
DE   AltName: Full=Nuclear matrix transcription factor 4;
DE            Short=Nuclear matrix protein 4;
DE   AltName: Full=Trinucleotide repeat-containing gene 1 protein;
GN   Name=ZNF384; Synonyms=CAGH1, CIZ, NMP4, TNRC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0050714; P:positive regulation of protein secretion; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN391_HUMAN             Reviewed;         358 AA.
AC   Q9UJN7; B4DH77;
DE   RecName: Full=Zinc finger protein 391;
GN   Name=ZNF391;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN394_HUMAN             Reviewed;         561 AA.
AC   Q53GI3; A4D281; Q6P5X9; Q8TB27; Q9HA37; Q9UD51;
DE   RecName: Full=Zinc finger protein 394;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 14;
GN   Name=ZNF394; Synonyms=ZKSCAN14;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN395_HUMAN             Reviewed;         513 AA.
AC   Q9H8N7; B3KUY7; D3DST4; Q6F6H2; Q9BY72; Q9NPB2; Q9NS57; Q9NS58;
AC   Q9NS59;
DE   RecName: Full=Zinc finger protein 395;
DE   AltName: Full=HD-regulating factor 2;
DE            Short=HDRF-2;
DE   AltName: Full=Huntington disease gene regulatory region-binding protein 2;
DE            Short=HD gene regulatory region-binding protein 2;
DE            Short=HDBP-2;
DE   AltName: Full=Papillomavirus regulatory factor 1;
DE            Short=PRF-1;
DE   AltName: Full=Papillomavirus-binding factor;
GN   Name=ZNF395; Synonyms=HDBP2, PBF;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IC:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN396_HUMAN             Reviewed;         335 AA.
AC   Q96N95; A1L3V0; Q8NF98; Q8TD80;
DE   RecName: Full=Zinc finger protein 396;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 14;
GN   Name=ZNF396; Synonyms=ZSCAN14;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN397_HUMAN             Reviewed;         534 AA.
AC   Q8NF99; Q9BRM2;
DE   RecName: Full=Zinc finger protein 397;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 15;
DE   AltName: Full=Zinc finger protein 47;
GN   Name=ZNF397; Synonyms=ZNF47, ZSCAN15;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN398_HUMAN             Reviewed;         642 AA.
AC   Q8TD17; A8K384; B4E377; Q8TD18; Q9P2K7; Q9UDV8;
DE   RecName: Full=Zinc finger protein 398;
DE   AltName: Full=Zinc finger DNA-binding protein p52/p71;
GN   Name=ZNF398; Synonyms=KIAA1339, ZER6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN3P1_HUMAN             Reviewed;         131 AA.
AC   Q17R26; A6NC11;
DE   RecName: Full=Putative protein ZNF300P1;
DE   AltName: Full=Zinc finger protein 300 pseudogene 1;
GN   Name=ZNF300P1;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ZN404_HUMAN             Reviewed;         552 AA.
AC   Q494X3; A4FU30; K7ELF2;
DE   RecName: Full=Zinc finger protein 404;
GN   Name=ZNF404;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN407_HUMAN             Reviewed;        2248 AA.
AC   Q9C0G0; B5MD54; Q96MY0; Q9H8A1; Q9NXD4; Q9NXD7;
DE   RecName: Full=Zinc finger protein 407;
GN   Name=ZNF407; Synonyms=KIAA1703;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN408_HUMAN             Reviewed;         720 AA.
AC   Q9H9D4;
DE   RecName: Full=Zinc finger protein 408;
DE   AltName: Full=PR domain zinc finger protein 17;
GN   Name=ZNF408; Synonyms=PFM14, PRDM17;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN410_HUMAN             Reviewed;         478 AA.
AC   Q86VK4; B4DDV5; B4DR78; O00153; Q9BQ19;
DE   RecName: Full=Zinc finger protein 410;
DE   AltName: Full=Another partner for ARF 1;
DE   AltName: Full=Zinc finger protein APA-1;
GN   Name=ZNF410; Synonyms=APA1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN414_HUMAN             Reviewed;         312 AA.
AC   Q96IQ9; A8MY94;
DE   RecName: Full=Zinc finger protein 414;
GN   Name=ZNF414;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN416_HUMAN             Reviewed;         594 AA.
AC   Q9BWM5; Q9NWW8;
DE   RecName: Full=Zinc finger protein 416;
GN   Name=ZNF416;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN415_HUMAN             Reviewed;         603 AA.
AC   Q09FC8; F5H287; Q09FC7; Q09FC9; Q09FD0; Q6NSZ2; Q6P3S0; Q9NUR2;
DE   RecName: Full=Zinc finger protein 415;
GN   Name=ZNF415;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN417_HUMAN             Reviewed;         575 AA.
AC   Q8TAU3;
DE   RecName: Full=Zinc finger protein 417;
GN   Name=ZNF417;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN418_HUMAN             Reviewed;         676 AA.
AC   Q8TF45; Q2M1S2; Q670L5; Q96N18;
DE   RecName: Full=Zinc finger protein 418;
GN   Name=ZNF418; Synonyms=KIAA1956;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN419_HUMAN             Reviewed;         510 AA.
AC   Q96HQ0; B4DXU7; B4E348; B7ZA41; E9PCP4; E9PED0; E9PET3; E9PFX9;
AC   Q9H5P0;
DE   RecName: Full=Zinc finger protein 419;
GN   Name=ZNF419; Synonyms=ZNF419A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN420_HUMAN             Reviewed;         688 AA.
AC   Q8TAQ5; B2RDY6;
DE   RecName: Full=Zinc finger protein 420;
GN   Name=ZNF420;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN423_HUMAN             Reviewed;        1284 AA.
AC   Q2M1K9; O94860; Q76N04; Q9NZ13;
DE   RecName: Full=Zinc finger protein 423;
DE   AltName: Full=Olf1/EBF-associated zinc finger protein;
DE            Short=hOAZ;
DE   AltName: Full=Smad- and Olf-interacting zinc finger protein;
GN   Name=ZNF423; Synonyms=KIAA0760, NPHP14, OAZ;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR   GO; GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.
DR   GO; GO:0030513; P:positive regulation of BMP signaling pathway; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN425_HUMAN             Reviewed;         752 AA.
AC   Q6IV72; B3KPM1; Q08AG3;
DE   RecName: Full=Zinc finger protein 425;
GN   Name=ZNF425;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN426_HUMAN             Reviewed;         554 AA.
AC   Q9BUY5; B3KTL2;
DE   RecName: Full=Zinc finger protein 426;
GN   Name=ZNF426;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN428_HUMAN             Reviewed;         188 AA.
AC   Q96B54; O95054; Q6X3Y3;
DE   RecName: Full=Zinc finger protein 428;
DE   AltName: Full=Enzyme-like protein PIT13;
GN   Name=ZNF428; Synonyms=C19orf37;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN429_HUMAN             Reviewed;         674 AA.
AC   Q86V71; A6NLV7; Q9BZE6;
DE   RecName: Full=Zinc finger protein 429;
GN   Name=ZNF429;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN430_HUMAN             Reviewed;         570 AA.
AC   Q9H8G1; Q86V70;
DE   RecName: Full=Zinc finger protein 430;
GN   Name=ZNF430;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0021762; P:substantia nigra development; IEP:UniProt.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN431_HUMAN             Reviewed;         576 AA.
AC   Q8TF32; A8KAK7; Q8IWC4;
DE   RecName: Full=Zinc finger protein 431;
GN   Name=ZNF431; Synonyms=KIAA1969;
DR   GO; GO:0003682; F:chromatin binding; ISS:UniProtKB.
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN432_HUMAN             Reviewed;         652 AA.
AC   O94892;
DE   RecName: Full=Zinc finger protein 432;
GN   Name=ZNF432; Synonyms=KIAA0798;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN433_HUMAN             Reviewed;         673 AA.
AC   Q8N7K0; Q86VX3;
DE   RecName: Full=Zinc finger protein 433;
GN   Name=ZNF433;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN436_HUMAN             Reviewed;         470 AA.
AC   Q9C0F3; Q658I9;
DE   RecName: Full=Zinc finger protein 436;
GN   Name=ZNF436; Synonyms=KIAA1710;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN438_HUMAN             Reviewed;         828 AA.
AC   Q7Z4V0; A2A3J4; A8K9L5; Q5T426; Q658Q4; Q6ZN65;
DE   RecName: Full=Zinc finger protein 438;
GN   Name=ZNF438;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN439_HUMAN             Reviewed;         499 AA.
AC   Q8NDP4; Q8IYZ7; Q96SU1;
DE   RecName: Full=Zinc finger protein 439;
GN   Name=ZNF439;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN440_HUMAN             Reviewed;         595 AA.
AC   Q8IYI8; Q8N1R9;
DE   RecName: Full=Zinc finger protein 440;
GN   Name=ZNF440;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN442_HUMAN             Reviewed;         627 AA.
AC   Q9H7R0;
DE   RecName: Full=Zinc finger protein 442;
GN   Name=ZNF442;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN441_HUMAN             Reviewed;         693 AA.
AC   Q8N8Z8;
DE   RecName: Full=Zinc finger protein 441;
GN   Name=ZNF441;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN443_HUMAN             Reviewed;         671 AA.
AC   Q9Y2A4;
DE   RecName: Full=Zinc finger protein 443;
DE   AltName: Full=Krueppel-type zinc finger protein ZK1;
GN   Name=ZNF443;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006950; P:response to stress; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN445_HUMAN             Reviewed;        1031 AA.
AC   P59923; Q3MJD1;
DE   RecName: Full=Zinc finger protein 445;
DE   AltName: Full=Zinc finger protein 168;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 15;
GN   Name=ZNF445; Synonyms=ZKSCAN15, ZNF168;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN444_HUMAN             Reviewed;         327 AA.
AC   Q8N0Y2; Q8TEQ9; Q8WU35; Q9NUU1;
DE   RecName: Full=Zinc finger protein 444;
DE   AltName: Full=Endothelial zinc finger protein 2;
DE            Short=EZF-2;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 17;
GN   Name=ZNF444; Synonyms=EZF2, ZSCAN17;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN446_HUMAN             Reviewed;         450 AA.
AC   Q9NWS9;
DE   RecName: Full=Zinc finger protein 446;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 20;
GN   Name=ZNF446; Synonyms=ZKSCAN20;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN449_HUMAN             Reviewed;         518 AA.
AC   Q6P9G9; Q5JRZ7; Q5JRZ8; Q6NZX2; Q8N3Q1; Q8TED7;
DE   RecName: Full=Zinc finger protein 449;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 19;
GN   Name=ZNF449; Synonyms=ZSCAN19;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN451_HUMAN             Reviewed;        1061 AA.
AC   Q9Y4E5; Q5VVE9; Q5VVF1; Q86YE4; Q8N380; Q8TD15; Q9C0G1; Q9NQM1;
DE   RecName: Full=Zinc finger protein 451;
DE   AltName: Full=Coactivator for steroid receptors;
GN   Name=ZNF451; Synonyms=COASTER, KIAA0576, KIAA1702;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN454_HUMAN             Reviewed;         522 AA.
AC   Q8N9F8; Q2M1P2; Q2M323;
DE   RecName: Full=Zinc finger protein 454;
GN   Name=ZNF454;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN460_HUMAN             Reviewed;         562 AA.
AC   Q14592; A4FU64; Q2VPC7; Q6VSF8;
DE   RecName: Full=Zinc finger protein 460;
DE   AltName: Full=Zinc finger protein 272;
DE   AltName: Full=Zinc finger protein HZF8;
GN   Name=ZNF460; Synonyms=ZNF272;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN461_HUMAN             Reviewed;         563 AA.
AC   Q8TAF7; A8K9W9; Q6VSF7; Q9ULZ8;
DE   RecName: Full=Zinc finger protein 461;
DE   AltName: Full=Gonadotropin-inducible ovary transcription repressor 1;
DE            Short=GIOT-1;
GN   Name=ZNF461; Synonyms=GIOT1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN462_HUMAN             Reviewed;        2506 AA.
AC   Q96JM2; Q5T0T4; Q8N408;
DE   RecName: Full=Zinc finger protein 462;
GN   Name=ZNF462; Synonyms=KIAA1803;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006325; P:chromatin organization; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN467_HUMAN             Reviewed;         595 AA.
AC   Q7Z7K2;
DE   RecName: Full=Zinc finger protein 467;
GN   Name=ZNF467;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN469_HUMAN             Reviewed;        3925 AA.
AC   Q96JG9;
DE   RecName: Full=Zinc finger protein 469;
GN   Name=ZNF469; Synonyms=KIAA1858;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN468_HUMAN             Reviewed;         522 AA.
AC   Q5VIY5; A8MV20; Q5CZB8; Q5VIY4; Q68DI7;
DE   RecName: Full=Zinc finger protein 468;
GN   Name=ZNF468;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN470_HUMAN             Reviewed;         717 AA.
AC   Q6ECI4; A8MTW0; B9EGU1; Q6ZPA1; Q9Y2N9;
DE   RecName: Full=Zinc finger protein 470;
DE   AltName: Full=Chondrogenesis zinc finger protein 1;
DE            Short=CZF-1;
GN   Name=ZNF470; Synonyms=CZF1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN473_HUMAN             Reviewed;         871 AA.
AC   Q8WTR7; A8K8T7; Q9ULS9; Q9Y4Q7;
DE   RecName: Full=Zinc finger protein 473;
DE   AltName: Full=Zinc finger protein 100 homolog;
DE            Short=Zfp-100;
GN   Name=ZNF473; Synonyms=KIAA1141, ZFP100;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0006398; P:histone mRNA 3'-end processing; IDA:UniProtKB.
DR   GO; GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.
DR   GO; GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:Reactome.
//
ID   ZN471_HUMAN             Reviewed;         626 AA.
AC   Q9BX82; O75260; Q08AD6; Q08AD7; Q8N3V1; Q9P2F1;
DE   RecName: Full=Zinc finger protein 471;
DE   AltName: Full=EZFIT-related protein 1;
GN   Name=ZNF471; Synonyms=ERP1, KIAA1396;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN474_HUMAN             Reviewed;         364 AA.
AC   Q6S9Z5; A8K4M0; Q96M07;
DE   RecName: Full=Zinc finger protein 474;
DE   AltName: Full=Testis-specific zinc finger protein;
DE            Short=TSZFP;
GN   Name=ZNF474;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN479_HUMAN             Reviewed;         524 AA.
AC   Q96JC4;
DE   RecName: Full=Zinc finger protein 479;
DE   AltName: Full=Zinc finger protein Kr19;
DE            Short=HKr19;
GN   Name=ZNF479;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN480_HUMAN             Reviewed;         535 AA.
AC   Q8WV37; Q5JPG9; Q6P0Q4; Q8N1M5;
DE   RecName: Full=Zinc finger protein 480;
GN   Name=ZNF480;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN483_HUMAN             Reviewed;         744 AA.
AC   Q8TF39; Q5VZN2; Q8NAE1;
DE   RecName: Full=Zinc finger protein 483;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 16;
GN   Name=ZNF483; Synonyms=KIAA1962, ZKSCAN16;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN484_HUMAN             Reviewed;         852 AA.
AC   Q5JVG2; B1AL89; B4DRI2;
DE   RecName: Full=Zinc finger protein 484;
GN   Name=ZNF484;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN485_HUMAN             Reviewed;         441 AA.
AC   Q8NCK3; Q96CL0;
DE   RecName: Full=Zinc finger protein 485;
GN   Name=ZNF485;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN487_HUMAN             Reviewed;         448 AA.
AC   B1APH4; B1APH5;
DE   RecName: Full=Putative zinc finger protein 487;
DE   AltName: Full=KRAB domain only protein 1;
GN   Name=ZNF487; Synonyms=KRBO1, ZNF487P;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN486_HUMAN             Reviewed;         463 AA.
AC   Q96H40; Q0VG00;
DE   RecName: Full=Zinc finger protein 486;
DE   AltName: Full=KRAB domain only protein 2;
GN   Name=ZNF486; Synonyms=KRBO2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN488_HUMAN             Reviewed;         340 AA.
AC   Q96MN9;
DE   RecName: Full=Zinc finger protein 488;
GN   Name=ZNF488;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0014003; P:oligodendrocyte development; IBA:RefGenome.
DR   GO; GO:0048714; P:positive regulation of oligodendrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN492_HUMAN             Reviewed;         531 AA.
AC   Q9P255; Q08EI7; Q08EI8;
DE   RecName: Full=Zinc finger protein 492;
DE   AltName: Full=Zinc finger protein 115;
GN   Name=ZNF492; Synonyms=KIAA1473, ZNF115;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN490_HUMAN             Reviewed;         529 AA.
AC   Q9ULM2;
DE   RecName: Full=Zinc finger protein 490;
GN   Name=ZNF490; Synonyms=KIAA1198;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN491_HUMAN             Reviewed;         437 AA.
AC   Q8N8L2; Q3MJ35; Q8NAT8;
DE   RecName: Full=Zinc finger protein 491;
GN   Name=ZNF491;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN493_HUMAN             Reviewed;         646 AA.
AC   Q6ZR52; G5E974; Q59GM3; Q6ZSF6; Q8N1Z6; Q8N965; Q9BR99;
DE   RecName: Full=Zinc finger protein 493;
GN   Name=ZNF493;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN496_HUMAN             Reviewed;         587 AA.
AC   Q96IT1; Q8TBS2;
DE   RecName: Full=Zinc finger protein 496;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 17;
GN   Name=ZNF496; Synonyms=ZKSCAN17;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN497_HUMAN             Reviewed;         498 AA.
AC   Q6ZNH5; Q05AG8; Q0VF48; Q6ZTD2; Q9UIA8;
DE   RecName: Full=Zinc finger protein 497;
GN   Name=ZNF497;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN500_HUMAN             Reviewed;         480 AA.
AC   O60304; A8K6X7; Q0VAL2; Q96CQ8; Q9BTG0;
DE   RecName: Full=Zinc finger protein 500;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 18;
GN   Name=ZNF500; Synonyms=KIAA0557, ZKSCAN18;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN501_HUMAN             Reviewed;         271 AA.
AC   Q96CX3; B4DLY7; Q96NU9;
DE   RecName: Full=Zinc finger protein 501;
DE   AltName: Full=Zinc finger protein 52;
GN   Name=ZNF501; Synonyms=ZNF52;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN502_HUMAN             Reviewed;         544 AA.
AC   Q8TBZ5;
DE   RecName: Full=Zinc finger protein 502;
GN   Name=ZNF502;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN503_HUMAN             Reviewed;         646 AA.
AC   Q96F45; Q8NAC5; Q96E25; Q96IJ0;
DE   RecName: Full=Zinc finger protein 503;
GN   Name=ZNF503; Synonyms=NOLZ1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0070315; P:G1 to G0 transition involved in cell differentiation; IDA:UniProt.
DR   GO; GO:0008285; P:negative regulation of cell proliferation; IDA:UniProt.
DR   GO; GO:0010629; P:negative regulation of gene expression; IDA:UniProt.
DR   GO; GO:0061351; P:neural precursor cell proliferation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN506_HUMAN             Reviewed;         444 AA.
AC   Q5JVG8; B3KTH6;
DE   RecName: Full=Zinc finger protein 506;
GN   Name=ZNF506;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN507_HUMAN             Reviewed;         953 AA.
AC   Q8TCN5; A8K911; Q2TBF1; Q6MZU0; Q9UPR8;
DE   RecName: Full=Zinc finger protein 507;
GN   Name=ZNF507; Synonyms=KIAA1084;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN511_HUMAN             Reviewed;         262 AA.
AC   Q8NB15; A8K8L5; Q8WUP1; Q96BV2;
DE   RecName: Full=Zinc finger protein 511;
GN   Name=ZNF511;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN512_HUMAN             Reviewed;         567 AA.
AC   Q96ME7; B4DSM5; Q53RZ7; Q86XK6; Q96JM0;
DE   RecName: Full=Zinc finger protein 512;
GN   Name=ZNF512; Synonyms=KIAA1805;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN510_HUMAN             Reviewed;         683 AA.
AC   Q9Y2H8; Q5SZP5;
DE   RecName: Full=Zinc finger protein 510;
GN   Name=ZNF510; Synonyms=KIAA0972;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN513_HUMAN             Reviewed;         541 AA.
AC   Q8N8E2; A8K3S5; B7WP71; Q3ZCU1; Q68CJ1; Q86UZ3; Q8NDL8; Q96ML3;
DE   RecName: Full=Zinc finger protein 513;
GN   Name=ZNF513;
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
//
ID   ZN514_HUMAN             Reviewed;         400 AA.
AC   Q96K75; Q5JPJ3;
DE   RecName: Full=Zinc finger protein 514;
GN   Name=ZNF514;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN516_HUMAN             Reviewed;        1163 AA.
AC   Q92618;
DE   RecName: Full=Zinc finger protein 516;
GN   Name=ZNF516; Synonyms=KIAA0222;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN517_HUMAN             Reviewed;         492 AA.
AC   Q6ZMY9;
DE   RecName: Full=Zinc finger protein 517;
GN   Name=ZNF517;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN519_HUMAN             Reviewed;         540 AA.
AC   Q8TB69;
DE   RecName: Full=Zinc finger protein 519;
GN   Name=ZNF519;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN521_HUMAN             Reviewed;        1311 AA.
AC   Q96K83; A3QVP7; B0YJB7; Q8IXI0; Q8TES6; Q9C065; Q9HAL5; Q9UFK4;
DE   RecName: Full=Zinc finger protein 521;
DE   AltName: Full=Early hematopoietic zinc finger protein;
DE   AltName: Full=LYST-interacting protein 3;
GN   Name=ZNF521; Synonyms=EHZF, LIP3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN524_HUMAN             Reviewed;         264 AA.
AC   Q96C55; Q6NW31; Q96IL7;
DE   RecName: Full=Zinc finger protein 524;
GN   Name=ZNF524;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN526_HUMAN             Reviewed;         670 AA.
AC   Q8TF50; B3KV29; Q69YI2; Q96E24;
DE   RecName: Full=Zinc finger protein 526;
GN   Name=ZNF526; Synonyms=KIAA1951;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN525_HUMAN             Reviewed;         197 AA.
AC   Q8N782; Q8TF23;
DE   RecName: Full=Zinc finger protein 525;
GN   Name=ZNF525; Synonyms=KIAA1979;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN527_HUMAN             Reviewed;         609 AA.
AC   Q8NB42; B4DVL5;
DE   RecName: Full=Zinc finger protein 527;
GN   Name=ZNF527; Synonyms=KIAA1829;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN529_HUMAN             Reviewed;         563 AA.
AC   Q6P280; K7EKE1; Q9H731; Q9HCF7;
DE   RecName: Full=Zinc finger protein 529;
GN   Name=ZNF529; Synonyms=KIAA1615;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN530_HUMAN             Reviewed;         599 AA.
AC   Q6P9A1; O43340; Q9P220;
DE   RecName: Full=Zinc finger protein 530;
GN   Name=ZNF530; Synonyms=KIAA1508;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN528_HUMAN             Reviewed;         628 AA.
AC   Q3MIS6; B3KPN4; Q86T88; Q96JK0;
DE   RecName: Full=Zinc finger protein 528;
GN   Name=ZNF528; Synonyms=KIAA1827;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN534_HUMAN             Reviewed;         674 AA.
AC   Q76KX8; Q76KX9;
DE   RecName: Full=Zinc finger protein 534;
DE   AltName: Full=KRAB domain only protein 3;
GN   Name=ZNF534; Synonyms=KRBO3;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN532_HUMAN             Reviewed;        1301 AA.
AC   Q9HCE3; Q4G0V6; Q7L7Z7; Q96QR7; Q9NVJ6;
DE   RecName: Full=Zinc finger protein 532;
GN   Name=ZNF532; Synonyms=KIAA1629;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN536_HUMAN             Reviewed;        1300 AA.
AC   O15090; A2RU18;
DE   RecName: Full=Zinc finger protein 536;
GN   Name=ZNF536; Synonyms=KIAA0390;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044323; F:retinoic acid-responsive element binding; IEA:Ensembl.
DR   GO; GO:0045665; P:negative regulation of neuron differentiation; IEA:Ensembl.
DR   GO; GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN540_HUMAN             Reviewed;         660 AA.
AC   Q8NDQ6; A0AVS5; A8K371; Q05D58; Q3LIC5; Q6ZN36; Q7Z3C8; Q86T31;
DE   RecName: Full=Zinc finger protein 540;
GN   Name=ZNF540; ORFNames=Nbla10512;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0000900; F:translation repressor activity, nucleic acid binding; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0017148; P:negative regulation of translation; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN541_HUMAN             Reviewed;        1365 AA.
AC   Q9H0D2; Q8NDK8;
DE   RecName: Full=Zinc finger protein 541;
GN   Name=ZNF541;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN542_HUMAN             Reviewed;         170 AA.
AC   Q5EBM4; B3KUG2; B4DLV1; Q6N061;
DE   RecName: Full=Putative zinc finger protein 542;
GN   Name=ZNF542;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN543_HUMAN             Reviewed;         600 AA.
AC   Q08ER8; Q495U9; Q495V0; Q6ZMP4; Q8NCX4;
DE   RecName: Full=Zinc finger protein 543;
GN   Name=ZNF543;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN544_HUMAN             Reviewed;         715 AA.
AC   Q6NX49; A8K6J1; Q9UEX4;
DE   RecName: Full=Zinc finger protein 544;
GN   Name=ZNF544;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN547_HUMAN             Reviewed;         402 AA.
AC   Q8IVP9; A8K5Z9; Q96NC4;
DE   RecName: Full=Zinc finger protein 547;
GN   Name=ZNF547;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN546_HUMAN             Reviewed;         836 AA.
AC   Q86UE3; A8K913;
DE   RecName: Full=Zinc finger protein 546;
DE   AltName: Full=Zinc finger protein 49;
GN   Name=ZNF546; Synonyms=ZNF49;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN549_HUMAN             Reviewed;         640 AA.
AC   Q6P9A3; B3KV91; O43336; Q8NAR4;
DE   RecName: Full=Zinc finger protein 549;
GN   Name=ZNF549;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN548_HUMAN             Reviewed;         533 AA.
AC   Q8NEK5; Q96M05;
DE   RecName: Full=Zinc finger protein 548;
GN   Name=ZNF548;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN550_HUMAN             Reviewed;         422 AA.
AC   Q7Z398; B3KVF6; O43337; Q7Z6D7; Q8NE45;
DE   RecName: Full=Zinc finger protein 550;
GN   Name=ZNF550;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN551_HUMAN             Reviewed;         670 AA.
AC   Q7Z340; B4DU22; P17034; Q8N246; Q9BRY1;
DE   RecName: Full=Zinc finger protein 551;
DE   AltName: Full=Zinc finger protein KOX23;
GN   Name=ZNF551; Synonyms=KOX23;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN554_HUMAN             Reviewed;         538 AA.
AC   Q86TJ5; Q8NAT3; Q9BWN3;
DE   RecName: Full=Zinc finger protein 554;
GN   Name=ZNF554;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN555_HUMAN             Reviewed;         628 AA.
AC   Q8NEP9; A8KA89; K7EQM2; Q8NA46; Q96MP1;
DE   RecName: Full=Zinc finger protein 555;
GN   Name=ZNF555;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN556_HUMAN             Reviewed;         456 AA.
AC   Q9HAH1; Q96GM3;
DE   RecName: Full=Zinc finger protein 556;
GN   Name=ZNF556;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN557_HUMAN             Reviewed;         423 AA.
AC   Q8N988; Q6PEJ3; Q9BTZ1;
DE   RecName: Full=Zinc finger protein 557;
GN   Name=ZNF557;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN558_HUMAN             Reviewed;         402 AA.
AC   Q96NG5; A8K5F0;
DE   RecName: Full=Zinc finger protein 558;
GN   Name=ZNF558;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN552_HUMAN             Reviewed;         407 AA.
AC   Q9H707; B3KUE9; Q6P5A6;
DE   RecName: Full=Zinc finger protein 552;
GN   Name=ZNF552;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN559_HUMAN             Reviewed;         538 AA.
AC   Q9BR84; K7EMG6;
DE   RecName: Full=Zinc finger protein 559;
GN   Name=ZNF559;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN560_HUMAN             Reviewed;         790 AA.
AC   Q96MR9; Q495S9; Q495T1;
DE   RecName: Full=Zinc finger protein 560;
GN   Name=ZNF560;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN561_HUMAN             Reviewed;         486 AA.
AC   Q8N587; Q6PJS0;
DE   RecName: Full=Zinc finger protein 561;
GN   Name=ZNF561;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN563_HUMAN             Reviewed;         476 AA.
AC   Q8TA94; B2R9E7; Q8NAT7;
DE   RecName: Full=Zinc finger protein 563;
GN   Name=ZNF563;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN562_HUMAN             Reviewed;         426 AA.
AC   Q6V9R5; Q32MN2; Q9NXS5;
DE   RecName: Full=Zinc finger protein 562;
GN   Name=ZNF562;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN564_HUMAN             Reviewed;         553 AA.
AC   Q8TBZ8; B9EGT4; Q6P1K6;
DE   RecName: Full=Zinc finger protein 564;
GN   Name=ZNF564;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN565_HUMAN             Reviewed;         499 AA.
AC   Q8N9K5; Q6NUS2;
DE   RecName: Full=Zinc finger protein 565;
GN   Name=ZNF565;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN566_HUMAN             Reviewed;         418 AA.
AC   Q969W8; B7ZL95; Q2M3J1;
DE   RecName: Full=Zinc finger protein 566;
GN   Name=ZNF566;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN567_HUMAN             Reviewed;         647 AA.
AC   Q8N184; B3KX49; Q6N044;
DE   RecName: Full=Zinc finger protein 567;
GN   Name=ZNF567;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN568_HUMAN             Reviewed;         644 AA.
AC   Q3ZCX4; B4DS92; E7ER33; Q6N060; Q8NA64;
DE   RecName: Full=Zinc finger protein 568;
GN   Name=ZNF568;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN569_HUMAN             Reviewed;         686 AA.
AC   Q5MCW4; A8K1S2; Q15925; Q96MQ2;
DE   RecName: Full=Zinc finger protein 569;
GN   Name=ZNF569;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN570_HUMAN             Reviewed;         536 AA.
AC   Q96NI8; A1L472;
DE   RecName: Full=Zinc finger protein 570;
GN   Name=ZNF570;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN571_HUMAN             Reviewed;         609 AA.
AC   Q7Z3V5; Q2HIY0; Q3ZCU3; Q9NZX7;
DE   RecName: Full=Zinc finger protein 571;
GN   Name=ZNF571; ORFNames=HSPC059;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN572_HUMAN             Reviewed;         529 AA.
AC   Q7Z3I7; A1L4F1; Q8N1Q0;
DE   RecName: Full=Zinc finger protein 572;
GN   Name=ZNF572;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN573_HUMAN             Reviewed;         645 AA.
AC   Q86YE8; B7WPE1; Q6P1P1; Q7Z7Q3; Q8N2Q1; Q96BM3; Q96NH0;
DE   RecName: Full=Zinc finger protein 573;
GN   Name=ZNF573;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN574_HUMAN             Reviewed;         896 AA.
AC   Q6ZN55; Q6IPE0; Q6ZN10; Q7L5Z5; Q8NCE3; Q9H6N0;
DE   RecName: Full=Zinc finger protein 574;
GN   Name=ZNF574;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN575_HUMAN             Reviewed;         245 AA.
AC   Q86XF7; B4DX54;
DE   RecName: Full=Zinc finger protein 575;
GN   Name=ZNF575;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN576_HUMAN             Reviewed;         170 AA.
AC   Q9H609; Q9BU03;
DE   RecName: Full=Zinc finger protein 576;
GN   Name=ZNF576;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN577_HUMAN             Reviewed;         485 AA.
AC   Q9BSK1; A8K0B4; A8K6Z7; C9JFB9;
DE   RecName: Full=Zinc finger protein 577;
GN   Name=ZNF577;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN578_HUMAN             Reviewed;         590 AA.
AC   Q96N58; B4DR51; I3L1Y6;
DE   RecName: Full=Zinc finger protein 578;
GN   Name=ZNF578;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN579_HUMAN             Reviewed;         562 AA.
AC   Q8NAF0;
DE   RecName: Full=Zinc finger protein 579;
GN   Name=ZNF579;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN580_HUMAN             Reviewed;         172 AA.
AC   Q9UK33; B2RC05; Q9NPP7;
DE   RecName: Full=Zinc finger protein 580;
DE   AltName: Full=LDL-induced EC protein;
GN   Name=ZNF580;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070301; P:cellular response to hydrogen peroxide; IDA:UniProtKB.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.
DR   GO; GO:0010595; P:positive regulation of endothelial cell migration; IDA:UniProtKB.
DR   GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IDA:UniProtKB.
DR   GO; GO:0032757; P:positive regulation of interleukin-8 production; IDA:UniProtKB.
DR   GO; GO:0002690; P:positive regulation of leukocyte chemotaxis; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN581_HUMAN             Reviewed;         197 AA.
AC   Q9P0T4; B2RDM6;
DE   RecName: Full=Zinc finger protein 581;
GN   Name=ZNF581; ORFNames=HSPC189;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN582_HUMAN             Reviewed;         517 AA.
AC   Q96NG8; B4DQZ9; B7Z9R3; Q6PJT6;
DE   RecName: Full=Zinc finger protein 582;
GN   Name=ZNF582;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN583_HUMAN             Reviewed;         569 AA.
AC   Q96ND8; O14850; Q2NKK3;
DE   RecName: Full=Zinc finger protein 583;
DE   AltName: Full=Zinc finger protein L3-5;
GN   Name=ZNF583;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN586_HUMAN             Reviewed;         402 AA.
AC   Q9NXT0; A0JLV8; A8MY63; B3KTS9; E7ERT1; G3XAH3;
DE   RecName: Full=Zinc finger protein 586;
GN   Name=ZNF586;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN587_HUMAN             Reviewed;         575 AA.
AC   Q96SQ5; A0AV72; G3V0H5; Q6ZMK8;
DE   RecName: Full=Zinc finger protein 587;
GN   Name=ZNF587;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN584_HUMAN             Reviewed;         421 AA.
AC   Q8IVC4; A8K203;
DE   RecName: Full=Zinc finger protein 584;
GN   Name=ZNF584;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN589_HUMAN             Reviewed;         364 AA.
AC   Q86UQ0; Q86UC9; Q9BRI6; Q9BRY3; Q9Y611; Q9Y612;
DE   RecName: Full=Zinc finger protein 589;
DE   AltName: Full=Stem cell zinc finger protein 1;
GN   Name=ZNF589; Synonyms=SZF1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ZN592_HUMAN             Reviewed;        1267 AA.
AC   Q92610; Q2M1T2; Q504Y9;
DE   RecName: Full=Zinc finger protein 592;
GN   Name=ZNF592; Synonyms=KIAA0211;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008219; P:cell death; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN593_HUMAN             Reviewed;         134 AA.
AC   O00488; B2R4S0; Q5T2H7;
DE   RecName: Full=Zinc finger protein 593;
DE   AltName: Full=Zinc finger protein T86;
GN   Name=ZNF593;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN594_HUMAN             Reviewed;         807 AA.
AC   Q96JF6; Q6RFS0;
DE   RecName: Full=Zinc finger protein 594;
DE   AltName: Full=Zinc finger protein HZF18;
GN   Name=ZNF594; Synonyms=KIAA1871;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN595_HUMAN             Reviewed;         648 AA.
AC   Q8IYB9;
DE   RecName: Full=Zinc finger protein 595;
GN   Name=ZNF595;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN596_HUMAN             Reviewed;         504 AA.
AC   Q8TC21; B2R8P4; O95015; Q8N9X0;
DE   RecName: Full=Zinc finger protein 596;
GN   Name=ZNF596;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN597_HUMAN             Reviewed;         424 AA.
AC   Q96LX8;
DE   RecName: Full=Zinc finger protein 597;
GN   Name=ZNF597;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN598_HUMAN             Reviewed;         904 AA.
AC   Q86UK7; Q8IW49; Q8N3D9; Q96FG3; Q9H7J3;
DE   RecName: Full=Zinc finger protein 598;
GN   Name=ZNF598;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZN599_HUMAN             Reviewed;         588 AA.
AC   Q96NL3; Q569K0; Q5PRG1;
DE   RecName: Full=Zinc finger protein 599;
GN   Name=ZNF599;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN600_HUMAN             Reviewed;         722 AA.
AC   Q6ZNG1; Q6MZR0;
DE   RecName: Full=Zinc finger protein 600;
GN   Name=ZNF600;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN605_HUMAN             Reviewed;         641 AA.
AC   Q86T29; B3KVG4; D3DXJ0; Q86T91;
DE   RecName: Full=Zinc finger protein 605;
GN   Name=ZNF605;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN606_HUMAN             Reviewed;         792 AA.
AC   Q8WXB4; A8KAN2; Q8NE04; Q96JH5;
DE   RecName: Full=Zinc finger protein 606;
DE   AltName: Full=Zinc finger protein 328;
GN   Name=ZNF606; Synonyms=KIAA1852, ZNF328;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN607_HUMAN             Reviewed;         696 AA.
AC   Q96SK3; F5H141; Q6ZMN2; Q6ZMN4; Q96C40;
DE   RecName: Full=Zinc finger protein 607;
GN   Name=ZNF607;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN608_HUMAN             Reviewed;        1512 AA.
AC   Q9ULD9; A7E2W9; Q3SYM6; Q68D12; Q8IY05; Q9Y5A1;
DE   RecName: Full=Zinc finger protein 608;
DE   AltName: Full=Renal carcinoma antigen NY-REN-36;
GN   Name=ZNF608; Synonyms=KIAA1281;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN609_HUMAN             Reviewed;        1411 AA.
AC   O15014; Q0D2I2;
DE   RecName: Full=Zinc finger protein 609;
GN   Name=ZNF609; Synonyms=KIAA0295;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN611_HUMAN             Reviewed;         705 AA.
AC   Q8N823; B3KRD5; Q69YG9;
DE   RecName: Full=Zinc finger protein 611;
GN   Name=ZNF611;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN613_HUMAN             Reviewed;         617 AA.
AC   Q6PF04; Q96SS9;
DE   RecName: Full=Zinc finger protein 613;
GN   Name=ZNF613;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN610_HUMAN             Reviewed;         462 AA.
AC   Q8N9Z0; A8K4C3; Q86YH8; Q8NDS9;
DE   RecName: Full=Zinc finger protein 610;
GN   Name=ZNF610;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN614_HUMAN             Reviewed;         585 AA.
AC   Q8N883; Q494T8; Q8TCF4;
DE   RecName: Full=Zinc finger protein 614;
GN   Name=ZNF614;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN615_HUMAN             Reviewed;         731 AA.
AC   Q8N8J6; B7ZKW9; Q2M2Y6; Q5CZB0; Q6ZMT7; Q6ZRB3;
DE   RecName: Full=Zinc finger protein 615;
GN   Name=ZNF615;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN616_HUMAN             Reviewed;         781 AA.
AC   Q08AN1; B3KRV1; Q0P658; Q658V7;
DE   RecName: Full=Zinc finger protein 616;
GN   Name=ZNF616;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN618_HUMAN             Reviewed;         954 AA.
AC   Q5T7W0; Q4G0X6; Q5T7W1; Q6ZT53; Q7Z6B9; Q8TF49; Q96E49;
DE   RecName: Full=Zinc finger protein 618;
GN   Name=ZNF618; Synonyms=KIAA1952;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN619_HUMAN             Reviewed;         560 AA.
AC   Q8N2I2; B4E271;
DE   RecName: Full=Zinc finger protein 619;
GN   Name=ZNF619;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN620_HUMAN             Reviewed;         422 AA.
AC   Q6ZNG0; Q8N223;
DE   RecName: Full=Zinc finger protein 620;
GN   Name=ZNF620;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN621_HUMAN             Reviewed;         439 AA.
AC   Q6ZSS3; Q14DC7; Q8TE91;
DE   RecName: Full=Zinc finger protein 621;
GN   Name=ZNF621;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN623_HUMAN             Reviewed;         536 AA.
AC   O75123; A4FU80; B4DGP3; E7ENV5;
DE   RecName: Full=Zinc finger protein 623;
GN   Name=ZNF623; Synonyms=KIAA0628;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN624_HUMAN             Reviewed;         865 AA.
AC   Q9P2J8; Q3SY62; Q3SY63; Q6ZN27;
DE   RecName: Full=Zinc finger protein 624;
GN   Name=ZNF624; Synonyms=KIAA1349;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN622_HUMAN             Reviewed;         477 AA.
AC   Q969S3;
DE   RecName: Full=Zinc finger protein 622;
DE   AltName: Full=Zinc finger-like protein 9;
GN   Name=ZNF622; Synonyms=ZPR9;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0008631; P:intrinsic apoptotic signaling pathway in response to oxidative stress; IDA:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IDA:UniProtKB.
DR   GO; GO:0043410; P:positive regulation of MAPK cascade; IDA:UniProtKB.
//
ID   ZN625_HUMAN             Reviewed;         306 AA.
AC   Q96I27; A4FU45; I3L0E9;
DE   RecName: Full=Zinc finger protein 625;
GN   Name=ZNF625;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN626_HUMAN             Reviewed;         528 AA.
AC   Q68DY1; Q8N8T4; Q96QM1;
DE   RecName: Full=Zinc finger protein 626;
GN   Name=ZNF626;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN627_HUMAN             Reviewed;         461 AA.
AC   Q7L945; O14846; Q4KMP9; Q6NT81; Q9BRG4;
DE   RecName: Full=Zinc finger protein 627;
GN   Name=ZNF627;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN628_HUMAN             Reviewed;        1059 AA.
AC   Q5EBL2; Q86X34;
DE   RecName: Full=Zinc finger protein 628;
GN   Name=ZNF628;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN629_HUMAN             Reviewed;         869 AA.
AC   Q9UEG4; Q15938;
DE   RecName: Full=Zinc finger protein 629;
DE   AltName: Full=Zinc finger protein 65;
GN   Name=ZNF629; Synonyms=KIAA0326, ZNF65;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN630_HUMAN             Reviewed;         657 AA.
AC   Q2M218; F8WAG4; Q5H8Z5;
DE   RecName: Full=Zinc finger protein 630;
GN   Name=ZNF630;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN638_HUMAN             Reviewed;        1978 AA.
AC   Q14966; B5MDV1; B7ZLD1; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7;
AC   Q8NF92; Q8TCA1; Q9H2G1; Q9NP37;
DE   RecName: Full=Zinc finger protein 638;
DE   AltName: Full=Cutaneous T-cell lymphoma-associated antigen se33-1;
DE            Short=CTCL-associated antigen se33-1;
DE   AltName: Full=Nuclear protein 220;
DE   AltName: Full=Zinc finger matrin-like protein;
GN   Name=ZNF638; Synonyms=NP220, ZFML;
DR   GO; GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN639_HUMAN             Reviewed;         485 AA.
AC   Q9UID6; A9X3Z9; D3DNR3;
DE   RecName: Full=Zinc finger protein 639;
DE   AltName: Full=Zinc finger protein ANC_2H01;
DE   AltName: Full=Zinc finger protein ZASC1;
GN   Name=ZNF639; Synonyms=ZASC1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043621; F:protein self-association; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0043922; P:negative regulation by host of viral transcription; IMP:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0043923; P:positive regulation by host of viral transcription; IMP:UniProtKB.
DR   GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IDA:UniProtKB.
//
ID   ZN641_HUMAN             Reviewed;         438 AA.
AC   Q96N77; B3KS43; B4DNU5; Q8TCQ7; Q8WVE1;
DE   RecName: Full=Zinc finger protein 641;
GN   Name=ZNF641;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN644_HUMAN             Reviewed;        1327 AA.
AC   Q9H582; A2RU71; Q2TAM0; Q5TCC0; Q6BEP7; Q6P446; Q6PI06; Q7LG67;
AC   Q9ULJ9;
DE   RecName: Full=Zinc finger protein 644;
DE   AltName: Full=Zinc finger motif enhancer-binding protein 2;
DE            Short=Zep-2;
GN   Name=ZNF644; Synonyms=KIAA1221, ZEP2;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN646_HUMAN             Reviewed;        1829 AA.
AC   O15015; Q8IVD8;
DE   RecName: Full=Zinc finger protein 646;
GN   Name=ZNF646; Synonyms=KIAA0296;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN645_HUMAN             Reviewed;         425 AA.
AC   Q8N7E2; A0AV29; A0AV31; Q6DJY9;
DE   RecName: Full=E3 ubiquitin-protein ligase ZNF645;
DE            EC=6.3.2.-;
DE   AltName: Full=Zinc finger protein 645;
GN   Name=ZNF645;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ZN649_HUMAN             Reviewed;         505 AA.
AC   Q9BS31; A8MYJ5; B2RDC4; Q9H9N2;
DE   RecName: Full=Zinc finger protein 649;
GN   Name=ZNF649;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN652_HUMAN             Reviewed;         606 AA.
AC   Q9Y2D9; A4QPD9; Q5H9Q0;
DE   RecName: Full=Zinc finger protein 652;
GN   Name=ZNF652; Synonyms=KIAA0924;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN648_HUMAN             Reviewed;         568 AA.
AC   Q5T619; B2RP16;
DE   RecName: Full=Zinc finger protein 648;
GN   Name=ZNF648;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN653_HUMAN             Reviewed;         615 AA.
AC   Q96CK0; Q96AS7;
DE   RecName: Full=Zinc finger protein 653;
DE   AltName: Full=67 kDa zinc finger protein;
DE   AltName: Full=Zinc finger protein Zip67;
GN   Name=ZNF653; Synonyms=ZIP67;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN654_HUMAN             Reviewed;         581 AA.
AC   Q8IZM8; Q9H791; Q9NV14;
DE   RecName: Full=Zinc finger protein 654;
DE   AltName: Full=Melanoma-associated antigen;
GN   Name=ZNF654;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN655_HUMAN             Reviewed;         491 AA.
AC   Q8N720; A4D291; A6NGD3; B4E3M4; B7Z9Q9; D6W5T4; Q8IV00; Q8TA89;
AC   Q96EZ3; Q9BQ85;
DE   RecName: Full=Zinc finger protein 655;
DE   AltName: Full=Vav-interacting Krueppel-like protein;
GN   Name=ZNF655; Synonyms=VIK;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN658_HUMAN             Reviewed;        1059 AA.
AC   Q5TYW1; Q6PIP3; Q96M55; Q9H9S6; Q9UG02;
DE   RecName: Full=Zinc finger protein 658;
GN   Name=ZNF658;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN660_HUMAN             Reviewed;         331 AA.
AC   Q6AZW8; Q7Z331; Q8N9M8;
DE   RecName: Full=Zinc finger protein 660;
GN   Name=ZNF660;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN664_HUMAN             Reviewed;         261 AA.
AC   Q8N3J9; B3KP97; Q15914; Q3ZCQ7;
DE   RecName: Full=Zinc finger protein 664;
DE   AltName: Full=Zinc finger protein 176;
DE   AltName: Full=Zinc finger protein from organ of Corti;
GN   Name=ZNF664; Synonyms=ZFOC1, ZNF196;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN662_HUMAN             Reviewed;         426 AA.
AC   Q6ZS27; A1A4T9; F8W7S8; Q6ZNF8; Q6ZQW8;
DE   RecName: Full=Zinc finger protein 662;
GN   Name=ZNF662;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN665_HUMAN             Reviewed;         613 AA.
AC   Q9H7R5; A8K5T8;
DE   RecName: Full=Zinc finger protein 665;
DE   AltName: Full=Zinc finger protein 160-like;
GN   Name=ZNF665; Synonyms=ZFP160L;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN667_HUMAN             Reviewed;         610 AA.
AC   Q5HYK9; B2RMS6; B9EK36; Q6B093; Q9H807;
DE   RecName: Full=Zinc finger protein 667;
GN   Name=ZNF667;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN668_HUMAN             Reviewed;         619 AA.
AC   Q96K58; C9JHH8; F5H7E7; Q59EV1; Q8N669; Q9H8L4;
DE   RecName: Full=Zinc finger protein 668;
GN   Name=ZNF668;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN670_HUMAN             Reviewed;         389 AA.
AC   Q9BS34;
DE   RecName: Full=Zinc finger protein 670;
GN   Name=ZNF670;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN671_HUMAN             Reviewed;         534 AA.
AC   Q8TAW3; A6NF07; Q9H5E9;
DE   RecName: Full=Zinc finger protein 671;
GN   Name=ZNF671;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN672_HUMAN             Reviewed;         452 AA.
AC   Q499Z4; Q96H65; Q96IM3; Q9H6G5;
DE   RecName: Full=Zinc finger protein 672;
GN   Name=ZNF672;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN669_HUMAN             Reviewed;         464 AA.
AC   Q96BR6; B3KP94; Q5VT39; Q9H9Q6;
DE   RecName: Full=Zinc finger protein 669;
GN   Name=ZNF669;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN674_HUMAN             Reviewed;         581 AA.
AC   Q2M3X9; B4DHE2; E9PHQ4;
DE   RecName: Full=Zinc finger protein 674;
GN   Name=ZNF674;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN675_HUMAN             Reviewed;         568 AA.
AC   Q8TD23; Q8N211;
DE   RecName: Full=Zinc finger protein 675;
DE   AltName: Full=TRAF6-binding zinc finger protein;
DE   AltName: Full=TRAF6-inhibitory zinc finger protein;
GN   Name=ZNF675; Synonyms=TIZ;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0045453; P:bone resorption; TAS:UniProtKB.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IDA:UniProtKB.
DR   GO; GO:2000660; P:negative regulation of interleukin-1-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.
DR   GO; GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.
DR   GO; GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
DR   GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.
DR   GO; GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IDA:BHF-UCL.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN676_HUMAN             Reviewed;         588 AA.
AC   Q8N7Q3; A8MVX5;
DE   RecName: Full=Zinc finger protein 676;
GN   Name=ZNF676;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN677_HUMAN             Reviewed;         584 AA.
AC   Q86XU0;
DE   RecName: Full=Zinc finger protein 677;
GN   Name=ZNF677;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN678_HUMAN             Reviewed;         525 AA.
AC   Q5SXM1; Q8IVQ9;
DE   RecName: Full=Zinc finger protein 678;
GN   Name=ZNF678;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN679_HUMAN             Reviewed;         411 AA.
AC   Q8IYX0;
DE   RecName: Full=Zinc finger protein 679;
GN   Name=ZNF679;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN680_HUMAN             Reviewed;         530 AA.
AC   Q8NEM1; B3KVJ4; Q6ZNF3; Q8NC79;
DE   RecName: Full=Zinc finger protein 680;
GN   Name=ZNF680;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN682_HUMAN             Reviewed;         498 AA.
AC   O95780; B3KU64; E9PFJ5; Q96JV9;
DE   RecName: Full=Zinc finger protein 682;
GN   Name=ZNF682;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN683_HUMAN             Reviewed;         524 AA.
AC   Q8IZ20; Q5T141; Q5T146; Q5T147; Q5T149; Q8NEN4;
DE   RecName: Full=Zinc finger protein 683;
GN   Name=ZNF683;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001779; P:natural killer cell differentiation; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN687_HUMAN             Reviewed;        1237 AA.
AC   Q8N1G0; D3DV17; Q68DQ8; Q9H937; Q9P2A7;
DE   RecName: Full=Zinc finger protein 687;
GN   Name=ZNF687; Synonyms=KIAA1441;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN684_HUMAN             Reviewed;         378 AA.
AC   Q5T5D7; Q2NKY4;
DE   RecName: Full=Zinc finger protein 684;
GN   Name=ZNF684;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN681_HUMAN             Reviewed;         645 AA.
AC   Q96N22; B3KVF7;
DE   RecName: Full=Zinc finger protein 681;
GN   Name=ZNF681;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN688_HUMAN             Reviewed;         276 AA.
AC   P0C7X2; A8MV39; B3KV51; O75701; Q8IW91; Q8WV14; Q96MN0;
DE   RecName: Full=Zinc finger protein 688;
GN   Name=ZNF688;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN689_HUMAN             Reviewed;         500 AA.
AC   Q96CS4; Q658J5;
DE   RecName: Full=Zinc finger protein 689;
GN   Name=ZNF689;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN691_HUMAN             Reviewed;         312 AA.
AC   Q5VV52; A8MXP6; B4DJR7; O95878; Q9NWE8;
DE   RecName: Full=Zinc finger protein 691;
GN   Name=ZNF691;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN692_HUMAN             Reviewed;         519 AA.
AC   Q9BU19; B4DXZ0; Q5SRA5; Q5SRA6; Q9HBC9; Q9NW93; Q9NWY6; Q9UF97;
DE   RecName: Full=Zinc finger protein 692;
GN   Name=ZNF692;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN696_HUMAN             Reviewed;         374 AA.
AC   Q9H7X3; A0AVE2;
DE   RecName: Full=Zinc finger protein 696;
GN   Name=ZNF696;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN697_HUMAN             Reviewed;         545 AA.
AC   Q5TEC3; Q96IT2;
DE   RecName: Full=Zinc finger protein 697;
GN   Name=ZNF697;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN695_HUMAN             Reviewed;         515 AA.
AC   Q8IW36; Q5T0N9; Q5T0P1; Q5T0P3; Q7Z2W8; Q7Z648;
DE   RecName: Full=Zinc finger protein 695;
DE   AltName: Full=Zinc finger protein SBZF3;
GN   Name=ZNF695;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ZN699_HUMAN             Reviewed;         642 AA.
AC   Q32M78; Q8N9A1;
DE   RecName: Full=Zinc finger protein 699;
DE   AltName: Full=Hangover homolog;
GN   Name=ZNF699;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN700_HUMAN             Reviewed;         742 AA.
AC   Q9H0M5; B9EGU4;
DE   RecName: Full=Zinc finger protein 700;
GN   Name=ZNF700;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN701_HUMAN             Reviewed;         465 AA.
AC   Q9NV72; A2RRM8; Q66K42;
DE   RecName: Full=Zinc finger protein 701;
GN   Name=ZNF701;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN702_HUMAN             Reviewed;         129 AA.
AC   Q9H963; Q05BW1;
DE   RecName: Full=Putative zinc finger protein 702;
GN   Name=ZNF702P; Synonyms=ZNF702;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN703_HUMAN             Reviewed;         590 AA.
AC   Q9H7S9; Q5XG76;
DE   RecName: Full=Zinc finger protein 703;
DE   AltName: Full=Zinc finger elbow-related proline domain protein 1;
GN   Name=ZNF703; Synonyms=ZEPPO1, ZPO1;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0034333; P:adherens junction assembly; ISS:UniProtKB.
DR   GO; GO:0071392; P:cellular response to estradiol stimulus; IDA:UniProtKB.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IDA:UniProtKB.
DR   GO; GO:0034111; P:negative regulation of homotypic cell-cell adhesion; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:UniProtKB.
DR   GO; GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IDA:UniProtKB.
DR   GO; GO:0060828; P:regulation of canonical Wnt signaling pathway; ISS:UniProtKB.
DR   GO; GO:0051726; P:regulation of cell cycle; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN704_HUMAN             Reviewed;         412 AA.
AC   Q6ZNC4; B2RNE6; B9EGW6;
DE   RecName: Full=Zinc finger protein 704;
GN   Name=ZNF704;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN706_HUMAN             Reviewed;          76 AA.
AC   Q9Y5V0; A8K362;
DE   RecName: Full=Zinc finger protein 706;
GN   Name=ZNF706; ORFNames=HSPC038, PNAS-113;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN707_HUMAN             Reviewed;         371 AA.
AC   Q96C28; A8K317; B3KNY1; D3DWK7;
DE   RecName: Full=Zinc finger protein 707;
GN   Name=ZNF707;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN708_HUMAN             Reviewed;         499 AA.
AC   P17019; Q6ZMR0;
DE   RecName: Full=Zinc finger protein 708;
DE   AltName: Full=Zinc finger protein 15;
DE   AltName: Full=Zinc finger protein 15-like 1;
DE   AltName: Full=Zinc finger protein KOX8;
GN   Name=ZNF708; Synonyms=KOX8, ZNF15, ZNF15L1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN709_HUMAN             Reviewed;         641 AA.
AC   Q8N972; A8K4E6;
DE   RecName: Full=Zinc finger protein 709;
GN   Name=ZNF709;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN710_HUMAN             Reviewed;         664 AA.
AC   Q8N1W2; A0AVS3; Q6ZMK9; Q8NDU0;
DE   RecName: Full=Zinc finger protein 710;
GN   Name=ZNF710;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN711_HUMAN             Reviewed;         761 AA.
AC   Q9Y462; B4DSV4; Q6NX42; Q9Y4J6;
DE   RecName: Full=Zinc finger protein 711;
DE   AltName: Full=Zinc finger protein 6;
GN   Name=ZNF711; Synonyms=CMPX1, ZNF6;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN713_HUMAN             Reviewed;         430 AA.
AC   Q8N859;
DE   RecName: Full=Zinc finger protein 713;
GN   Name=ZNF713;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN714_HUMAN             Reviewed;         554 AA.
AC   Q96N38; Q49AI1; Q86W65; Q8ND40;
DE   RecName: Full=Zinc finger protein 714;
GN   Name=ZNF714;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN717_HUMAN             Reviewed;         904 AA.
AC   Q9BY31;
DE   RecName: Full=Zinc finger protein 717;
DE   AltName: Full=Krueppel-like factor X17;
GN   Name=ZNF717;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN718_HUMAN             Reviewed;         478 AA.
AC   Q3SXZ3; Q3SXZ4; Q3SXZ5;
DE   RecName: Full=Zinc finger protein 718;
GN   Name=ZNF718;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN720_HUMAN             Reviewed;         126 AA.
AC   Q7Z2F6; Q6ZQX1;
DE   RecName: Full=Putative protein ZNF720;
GN   Name=ZNF720;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ZN716_HUMAN             Reviewed;         495 AA.
AC   A6NP11;
DE   RecName: Full=Zinc finger protein 716;
GN   Name=ZNF716;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN721_HUMAN             Reviewed;         911 AA.
AC   Q8TF20; Q69YG7;
DE   RecName: Full=Zinc finger protein 721;
GN   Name=ZNF721; Synonyms=KIAA1982;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN724_HUMAN             Reviewed;         619 AA.
AC   A8MTY0;
DE   RecName: Full=Putative zinc finger protein 724;
GN   Name=ZNF724P;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN726_HUMAN             Reviewed;         738 AA.
AC   A6NNF4; M0R0X8; Q86Y87;
DE   RecName: Full=Zinc finger protein 726;
GN   Name=ZNF726;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN728_HUMAN             Reviewed;         622 AA.
AC   P0DKX0;
DE   RecName: Full=Zinc finger protein 728;
GN   Name=ZNF728;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ZN727_HUMAN             Reviewed;         499 AA.
AC   A8MUV8;
DE   RecName: Full=Putative zinc finger protein 727;
GN   Name=ZNF727;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN729_HUMAN             Reviewed;        1252 AA.
AC   A6NN14; M0QY45;
DE   RecName: Full=Zinc finger protein 729;
GN   Name=ZNF729;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN735_HUMAN             Reviewed;         412 AA.
AC   P0CB33;
DE   RecName: Full=Putative zinc finger protein 735;
GN   Name=ZNF735;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN740_HUMAN             Reviewed;         193 AA.
AC   Q8NDX6; A8K9M9;
DE   RecName: Full=Zinc finger protein 740;
DE   AltName: Full=OriLyt TD-element-binding protein 7;
GN   Name=ZNF740; Synonyms=TB7;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN732_HUMAN             Reviewed;         585 AA.
AC   B4DXR9;
DE   RecName: Full=Zinc finger protein 732;
GN   Name=ZNF732;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN730_HUMAN             Reviewed;         503 AA.
AC   Q6ZMV8;
DE   RecName: Full=Putative zinc finger protein 730;
GN   Name=ZNF730;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN737_HUMAN             Reviewed;         536 AA.
AC   O75373; C9JHM3;
DE   RecName: Full=Zinc finger protein 737;
DE   AltName: Full=Zinc finger protein 102;
GN   Name=ZNF737; Synonyms=ZNF102;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN736_HUMAN             Reviewed;         427 AA.
AC   B4DX44;
DE   RecName: Full=Zinc finger protein 736;
GN   Name=ZNF736;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN738_HUMAN             Reviewed;         137 AA.
AC   Q8NE65; A8K4N7;
DE   RecName: Full=Protein ZNF738;
GN   Name=ZNF738;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN746_HUMAN             Reviewed;         644 AA.
AC   Q6NUN9; A8K6Z9; Q6ZRF9;
DE   RecName: Full=Zinc finger protein 746;
DE   AltName: Full=Parkin-interacting substrate;
DE            Short=PARIS;
GN   Name=ZNF746; Synonyms=PARIS;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0070997; P:neuron death; IDA:UniProtKB.
DR   GO; GO:0010941; P:regulation of cell death; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN747_HUMAN             Reviewed;         191 AA.
AC   Q9BV97; A8K827; B7WNU3; Q59FB4; Q96NW0;
DE   RecName: Full=KRAB domain-containing protein ZNF747;
GN   Name=ZNF747;
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
//
ID   ZN749_HUMAN             Reviewed;         778 AA.
AC   O43361;
DE   RecName: Full=Zinc finger protein 749;
GN   Name=ZNF749;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN750_HUMAN             Reviewed;         723 AA.
AC   Q32MQ0; Q9H899;
DE   RecName: Full=Zinc finger protein 750;
GN   Name=ZNF750;
DR   GO; GO:0001046; F:core promoter sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0008544; P:epidermis development; IMP:UniProtKB.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
//
ID   ZN75A_HUMAN             Reviewed;         296 AA.
AC   Q96N20; Q0VDI8; Q92669;
DE   RecName: Full=Zinc finger protein 75A;
GN   Name=ZNF75A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN75C_HUMAN             Reviewed;         426 AA.
AC   Q92670;
DE   RecName: Full=Putative zinc finger protein 75C;
DE   AltName: Full=Zinc finger protein 75C pseudogene;
GN   Name=ZNF75CP; Synonyms=ZNF75C;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN761_HUMAN             Reviewed;         746 AA.
AC   Q86XN6; Q6ZNB9;
DE   RecName: Full=Zinc finger protein 761;
GN   Name=ZNF761; Synonyms=KIAA2033;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN764_HUMAN             Reviewed;         408 AA.
AC   Q96H86; A8MZF4; B3KSN2; H9KV99; Q9BWS1;
DE   RecName: Full=Zinc finger protein 764;
GN   Name=ZNF764;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN765_HUMAN             Reviewed;         523 AA.
AC   Q7L2R6; A8MYG0; B4DF18; B7ZAI5; B9EIL1; Q9BV49;
DE   RecName: Full=Zinc finger protein 765;
GN   Name=ZNF765;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN75D_HUMAN             Reviewed;         510 AA.
AC   P51815; A6NK62; B3KRI7; Q5JPG0; Q6LDE0;
DE   RecName: Full=Zinc finger protein 75D;
DE   AltName: Full=Zinc finger protein 75;
DE   AltName: Full=Zinc finger protein 82;
GN   Name=ZNF75D; Synonyms=ZNF75, ZNF82;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN767_HUMAN             Reviewed;         155 AA.
AC   Q75MW2; D3DWG6; Q86WY4; Q9H9J3;
DE   RecName: Full=Protein ZNF767;
GN   Name=ZNF767;
//
ID   ZN763_HUMAN             Reviewed;         394 AA.
AC   Q0D2J5; B3KRU3;
DE   RecName: Full=Zinc finger protein 763;
GN   Name=ZNF763;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN766_HUMAN             Reviewed;         468 AA.
AC   Q5HY98; B2RNE0; Q7Z326;
DE   RecName: Full=Zinc finger protein 766;
GN   Name=ZNF766;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN770_HUMAN             Reviewed;         691 AA.
AC   Q6IQ21; Q6ZMZ6; Q9NWV2;
DE   RecName: Full=Zinc finger protein 770;
GN   Name=ZNF770;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZN768_HUMAN             Reviewed;         540 AA.
AC   Q9H5H4; Q569L7; Q96CX4;
DE   RecName: Full=Zinc finger protein 768;
GN   Name=ZNF768;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IEA:InterPro.
//
ID   ZN771_HUMAN             Reviewed;         317 AA.
AC   Q7L3S4; Q8TAQ7; Q9NYI6;
DE   RecName: Full=Zinc finger protein 771;
DE   AltName: Full=Mesenchymal stem cell protein DSC43;
GN   Name=ZNF771;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN772_HUMAN             Reviewed;         489 AA.
AC   Q68DY9; A6NJK9; B4DH56; B4DYS0;
DE   RecName: Full=Zinc finger protein 772;
GN   Name=ZNF772;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN773_HUMAN             Reviewed;         442 AA.
AC   Q6PK81; Q96DL8;
DE   RecName: Full=Zinc finger protein 773;
DE   AltName: Full=Zinc finger protein 419B;
GN   Name=ZNF773; Synonyms=ZNF419B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN774_HUMAN             Reviewed;         483 AA.
AC   Q6NX45; A8K020;
DE   RecName: Full=Zinc finger protein 774;
GN   Name=ZNF774;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN775_HUMAN             Reviewed;         537 AA.
AC   Q96BV0; Q8IY24;
DE   RecName: Full=Zinc finger protein 775;
GN   Name=ZNF775;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN776_HUMAN             Reviewed;         518 AA.
AC   Q68DI1; Q6ZS36; Q8N968;
DE   RecName: Full=Zinc finger protein 776;
GN   Name=ZNF776;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN777_HUMAN             Reviewed;         760 AA.
AC   Q9ULD5; Q8N2R2; Q8N659;
DE   RecName: Full=Zinc finger protein 777;
GN   Name=ZNF777; Synonyms=KIAA1285;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN778_HUMAN             Reviewed;         729 AA.
AC   Q96MU6; Q08AG0;
DE   RecName: Full=Zinc finger protein 778;
GN   Name=ZNF778;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN781_HUMAN             Reviewed;         355 AA.
AC   Q8N8C0; Q2VPJ8;
DE   RecName: Full=Zinc finger protein 781;
GN   Name=ZNF781;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN782_HUMAN             Reviewed;         699 AA.
AC   Q6ZMW2; B2RNR0;
DE   RecName: Full=Zinc finger protein 782;
GN   Name=ZNF782;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN783_HUMAN             Reviewed;         281 AA.
AC   Q6ZMS7;
DE   RecName: Full=Protein ZNF783;
GN   Name=ZNF783;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN784_HUMAN             Reviewed;         323 AA.
AC   Q8NCA9;
DE   RecName: Full=Zinc finger protein 784;
GN   Name=ZNF784;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN785_HUMAN             Reviewed;         405 AA.
AC   A8K8V0; O75701; Q8IW91; Q8WV14; Q96MN0;
DE   RecName: Full=Zinc finger protein 785;
GN   Name=ZNF785;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN786_HUMAN             Reviewed;         782 AA.
AC   Q8N393; A1A568;
DE   RecName: Full=Zinc finger protein 786;
GN   Name=ZNF786;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN787_HUMAN             Reviewed;         383 AA.
AC   Q6DD87; O00455;
DE   RecName: Full=Zinc finger protein 787;
DE   AltName: Full=TTF-I-interacting peptide 20;
GN   Name=ZNF787;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN789_HUMAN             Reviewed;         425 AA.
AC   Q5FWF6; A4D282; A6NH61; Q6ZMZ9;
DE   RecName: Full=Zinc finger protein 789;
GN   Name=ZNF789;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN788_HUMAN             Reviewed;         615 AA.
AC   Q6ZQV5; Q6ZRE4;
DE   RecName: Full=Zinc finger protein 788;
GN   Name=ZNF788;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN790_HUMAN             Reviewed;         636 AA.
AC   Q6PG37;
DE   RecName: Full=Zinc finger protein 790;
GN   Name=ZNF790;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN791_HUMAN             Reviewed;         576 AA.
AC   Q3KP31; Q8NC99;
DE   RecName: Full=Zinc finger protein 791;
GN   Name=ZNF791;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN792_HUMAN             Reviewed;         632 AA.
AC   Q3KQV3; B4E333; Q495L1; Q495L3; Q8N932;
DE   RecName: Full=Zinc finger protein 792;
GN   Name=ZNF792;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN793_HUMAN             Reviewed;         406 AA.
AC   Q6ZN11; E9PGN4; Q7Z3Q9;
DE   RecName: Full=Zinc finger protein 793;
GN   Name=ZNF793;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN800_HUMAN             Reviewed;         664 AA.
AC   Q2TB10; Q9HBN0;
DE   RecName: Full=Zinc finger protein 800;
GN   Name=ZNF800; ORFNames=PP902;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN799_HUMAN             Reviewed;         643 AA.
AC   Q96GE5;
DE   RecName: Full=Zinc finger protein 799;
DE   AltName: Full=Zinc finger protein 842;
GN   Name=ZNF799; Synonyms=ZNF842;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN805_HUMAN             Reviewed;         627 AA.
AC   Q5CZA5; B4DNM5;
DE   RecName: Full=Zinc finger protein 805;
GN   Name=ZNF805;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN806_HUMAN             Reviewed;         589 AA.
AC   P0C7X5;
DE   RecName: Full=Zinc finger protein 806;
GN   Name=ZNF806;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN808_HUMAN             Reviewed;         903 AA.
AC   Q8N4W9; Q68CN7;
DE   RecName: Full=Zinc finger protein 808;
GN   Name=ZNF808;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN812_HUMAN             Reviewed;         454 AA.
AC   P0C7V5;
DE   RecName: Full=Putative zinc finger protein 812;
GN   Name=ZNF812;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN813_HUMAN             Reviewed;         617 AA.
AC   Q6ZN06;
DE   RecName: Full=Zinc finger protein 813;
GN   Name=ZNF813;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN814_HUMAN             Reviewed;         855 AA.
AC   B7Z6K7; A6NF35;
DE   RecName: Full=Putative uncharacterized zinc finger protein 814;
DE   AltName: Full=Putative zinc finger protein LOC730051;
GN   Name=ZNF814;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   ZN816_HUMAN             Reviewed;         651 AA.
AC   Q0VGE8; A8K7H5; Q3KR39; Q659B3;
DE   RecName: Full=Zinc finger protein 816;
GN   Name=ZNF816; Synonyms=ZNF816A;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN815_HUMAN             Reviewed;         130 AA.
AC   A8K554;
DE   RecName: Full=Putative protein ZNF815;
GN   Name=ZNF815P; Synonyms=ZNF815;
//
ID   ZN821_HUMAN             Reviewed;         412 AA.
AC   O75541; A6NK48; B4DKK4; D3DWS3;
DE   RecName: Full=Zinc finger protein 821;
GN   Name=ZNF821;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN818_HUMAN             Reviewed;         136 AA.
AC   Q6ZRF7;
DE   RecName: Full=Putative zinc finger protein 818;
GN   Name=ZNF818P; Synonyms=ZNF818;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN827_HUMAN             Reviewed;        1081 AA.
AC   Q17R98; B7ZL52; Q7Z4S7; Q8N279;
DE   RecName: Full=Zinc finger protein 827;
GN   Name=ZNF827;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN823_HUMAN             Reviewed;         610 AA.
AC   P16415; A0PJL4; Q6P4A9;
DE   RecName: Full=Zinc finger protein 823;
DE   AltName: Full=Zinc finger protein ZFP-36;
GN   Name=ZNF823; Synonyms=ZFP36;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN826_HUMAN             Reviewed;         177 AA.
AC   Q6ZT77;
DE   RecName: Full=Putative zinc finger protein 826;
GN   Name=ZNF826P; Synonyms=ZNF826;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN829_HUMAN             Reviewed;         432 AA.
AC   Q3KNS6; Q3KNS7; Q6ZNN0; Q7Z657;
DE   RecName: Full=Zinc finger protein 829;
GN   Name=ZNF829;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN830_HUMAN             Reviewed;         372 AA.
AC   Q96NB3; Q96F60; Q96GZ5; Q9BU38;
DE   RecName: Full=Zinc finger protein 830;
DE   AltName: Full=Coiled-coil domain-containing protein 16;
GN   Name=ZNF830; Synonyms=CCDC16;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0001832; P:blastocyst growth; IEA:Ensembl.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0033260; P:nuclear cell cycle DNA replication; IEA:Ensembl.
//
ID   ZN835_HUMAN             Reviewed;         537 AA.
AC   Q9Y2P0; B7Z5Y0; G3V1S0;
DE   RecName: Full=Zinc finger protein 835;
GN   Name=ZNF835;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN831_HUMAN             Reviewed;        1677 AA.
AC   Q5JPB2; Q5TDR4; Q8TCP0;
DE   RecName: Full=Zinc finger protein 831;
GN   Name=ZNF831; Synonyms=C20orf174;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZN836_HUMAN             Reviewed;         936 AA.
AC   Q6ZNA1;
DE   RecName: Full=Zinc finger protein 836;
GN   Name=ZNF836;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN833_HUMAN             Reviewed;         187 AA.
AC   Q6ZTB9; B2RPA0;
DE   RecName: Full=Putative zinc finger protein 833;
GN   Name=ZNF833P; Synonyms=ZNF833;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZN837_HUMAN             Reviewed;         531 AA.
AC   Q96EG3;
DE   RecName: Full=Zinc finger protein 837;
GN   Name=ZNF837;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN839_HUMAN             Reviewed;         811 AA.
AC   A8K0R7; B3KSD2; Q53FH5; Q6GPI5; Q86TU1; Q9BQ86; Q9NUU3;
DE   RecName: Full=Zinc finger protein 839;
DE   AltName: Full=Renal carcinoma antigen NY-REN-50;
GN   Name=ZNF839; Synonyms=C14orf131;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZN841_HUMAN             Reviewed;         808 AA.
AC   Q6ZN19; B9EG58; Q6ZN82; Q6ZP71; Q8N9U7;
DE   RecName: Full=Zinc finger protein 841;
GN   Name=ZNF841;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN843_HUMAN             Reviewed;         348 AA.
AC   Q8N446; A8K4U8;
DE   RecName: Full=Zinc finger protein 843;
GN   Name=ZNF843;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZN844_HUMAN             Reviewed;         666 AA.
AC   Q08AG5; Q5JPI8;
DE   RecName: Full=Zinc finger protein 844;
GN   Name=ZNF844;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN845_HUMAN             Reviewed;         970 AA.
AC   Q96IR2;
DE   RecName: Full=Zinc finger protein 845;
GN   Name=ZNF845;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN840_HUMAN             Reviewed;         716 AA.
AC   A6NDX5; Q6KAL7;
DE   RecName: Full=Putative zinc finger protein 840;
GN   Name=ZNF840; Synonyms=C20orf157, ZNF840P;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN850_HUMAN             Reviewed;        1090 AA.
AC   A8MQ14;
DE   RecName: Full=Zinc finger protein 850;
GN   Name=ZNF850;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN846_HUMAN             Reviewed;         533 AA.
AC   Q147U1; A8K0H1; B3KUP1;
DE   RecName: Full=Zinc finger protein 846;
GN   Name=ZNF846;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN852_HUMAN             Reviewed;         509 AA.
AC   Q6ZMS4;
DE   RecName: Full=Putative zinc finger protein 852;
GN   Name=ZNF852;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZN860_HUMAN             Reviewed;         632 AA.
AC   A6NHJ4; B4DFA4;
DE   RecName: Full=Zinc finger protein 860;
GN   Name=ZNF860;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN853_HUMAN             Reviewed;         659 AA.
AC   P0CG23;
DE   RecName: Full=Zinc finger protein 853;
GN   Name=ZNF853;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZN861_HUMAN             Reviewed;         105 AA.
AC   O60384;
DE   RecName: Full=Putative zinc finger protein 861;
GN   Name=ZNF861P;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZN862_HUMAN             Reviewed;        1169 AA.
AC   O60290; A0AUL8;
DE   RecName: Full=Zinc finger protein 862;
GN   Name=ZNF862; Synonyms=KIAA0543;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN878_HUMAN             Reviewed;         531 AA.
AC   C9JN71;
DE   RecName: Full=Zinc finger protein 878;
GN   Name=ZNF878;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN879_HUMAN             Reviewed;         563 AA.
AC   B4DU55;
DE   RecName: Full=Zinc finger protein 879;
GN   Name=ZNF879;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN865_HUMAN             Reviewed;        1059 AA.
AC   P0CJ78;
DE   RecName: Full=Zinc finger protein 865;
GN   Name=ZNF865;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN888_HUMAN             Reviewed;         500 AA.
AC   P0CJ79;
DE   RecName: Full=Zinc finger protein 888;
GN   Name=ZNF888;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN880_HUMAN             Reviewed;         577 AA.
AC   Q6PDB4; B4DNA6;
DE   RecName: Full=Zinc finger protein 880;
GN   Name=ZNF880;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
//
ID   ZN883_HUMAN             Reviewed;         379 AA.
AC   P0CG24;
DE   RecName: Full=Zinc finger protein 883;
GN   Name=ZNF883;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZN891_HUMAN             Reviewed;         544 AA.
AC   A8MT65;
DE   RecName: Full=Zinc finger protein 891;
GN   Name=ZNF891;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF10_HUMAN             Reviewed;         573 AA.
AC   P21506; B2RBS1; Q8TC91;
DE   RecName: Full=Zinc finger protein 10;
DE   AltName: Full=Zinc finger protein KOX1;
GN   Name=ZNF10; Synonyms=KOX1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF12_HUMAN             Reviewed;         697 AA.
AC   P17014; A8MYC4; A8WFQ8; B2RNQ7; B4DF45; Q6N016; Q8NHZ0; Q9H9P0;
AC   Q9ULZ6;
DE   RecName: Full=Zinc finger protein 12;
DE   AltName: Full=Gonadotropin-inducible ovary transcription repressor 3;
DE            Short=GIOT-3;
DE   AltName: Full=Zinc finger protein 325;
DE   AltName: Full=Zinc finger protein KOX3;
GN   Name=ZNF12; Synonyms=GIOT3, KOX3, ZNF325;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNAS2_HUMAN             Reviewed;         195 AA.
AC   A6NEH8;
DE   RecName: Full=Putative uncharacterized protein encoded by ZNF503-AS2;
DE   AltName: Full=ZNF503 antisense RNA 2;
GN   Name=ZNF503-AS2; Synonyms=C10orf41, NCRNA00245;
//
ID   ZNAS1_HUMAN             Reviewed;         137 AA.
AC   Q8N0V1;
DE   RecName: Full=Putative uncharacterized protein ZNF295-AS1;
DE   AltName: Full=ZNF295 antisense RNA 1;
DE   AltName: Full=ZNF295 antisense gene protein 1;
GN   Name=ZNF295-AS1; Synonyms=C21orf121, NCRNA00318; ORFNames=PRED87;
//
ID   ZNF14_HUMAN             Reviewed;         642 AA.
AC   P17017; B9EGA4; Q9ULZ5;
DE   RecName: Full=Zinc finger protein 14;
DE   AltName: Full=Gonadotropin-inducible ovary transcription repressor 4;
DE            Short=GIOT-4;
DE   AltName: Full=Zinc finger protein KOX6;
GN   Name=ZNF14; Synonyms=GIOT4, KOX6;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF16_HUMAN             Reviewed;         682 AA.
AC   P17020; B3KXM4; D3DWP2; Q45SH7; Q96FG0; Q9NRA4;
DE   RecName: Full=Zinc finger protein 16;
DE   AltName: Full=Zinc finger protein KOX9;
GN   Name=ZNF16; Synonyms=HZF1, KOX9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0072707; P:cellular response to sodium dodecyl sulfate; IDA:UniProtKB.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
DR   GO; GO:1901989; P:positive regulation of cell cycle phase transition; IDA:UniProtKB.
DR   GO; GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW.
DR   GO; GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.
DR   GO; GO:0045648; P:positive regulation of erythrocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0033674; P:positive regulation of kinase activity; IDA:UniProtKB.
DR   GO; GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF17_HUMAN             Reviewed;         662 AA.
AC   P17021; B3KXU2; B3KY20; Q8N7M1; Q8N893; Q8TF54;
DE   RecName: Full=Zinc finger protein 17;
DE   AltName: Full=Zinc finger protein HPF3;
DE   AltName: Full=Zinc finger protein KOX10;
GN   Name=ZNF17; Synonyms=KIAA1947, KOX10;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF18_HUMAN             Reviewed;         549 AA.
AC   P17022; Q5QHQ3; Q8IYC4; Q8NAH6;
DE   RecName: Full=Zinc finger protein 18;
DE   AltName: Full=Heart development-specific gene 1 protein;
DE   AltName: Full=Zinc finger protein 535;
DE   AltName: Full=Zinc finger protein KOX11;
DE   AltName: Full=Zinc finger protein with KRAB and SCAN domains 6;
GN   Name=ZNF18; Synonyms=HDSG1, KOX11, ZKSCAN6, ZNF535;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZNF19_HUMAN             Reviewed;         458 AA.
AC   P17023; A8K895; Q86Y66; Q8NDE2; Q96M79; Q96NE5;
DE   RecName: Full=Zinc finger protein 19;
DE   AltName: Full=Zinc finger protein KOX12;
GN   Name=ZNF19; Synonyms=KOX12;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF20_HUMAN             Reviewed;         532 AA.
AC   P17024; Q8N457; Q9UG41;
DE   RecName: Full=Zinc finger protein 20;
DE   AltName: Full=Zinc finger protein KOX13;
GN   Name=ZNF20; Synonyms=KOX13;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF22_HUMAN             Reviewed;         224 AA.
AC   P17026; Q5T741; Q96FM4;
DE   RecName: Full=Zinc finger protein 22;
DE   AltName: Full=Zinc finger protein KOX15;
DE   AltName: Full=Zinc finger protein Krox-26;
GN   Name=ZNF22; Synonyms=KOX15, KROX26;
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; TAS:ProtInc.
DR   GO; GO:0042476; P:odontogenesis; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF23_HUMAN             Reviewed;         643 AA.
AC   P17027; Q96IT3; Q9UG42;
DE   RecName: Full=Zinc finger protein 23;
DE   AltName: Full=Zinc finger protein 359;
DE   AltName: Full=Zinc finger protein 612;
DE   AltName: Full=Zinc finger protein KOX16;
GN   Name=ZNF23; Synonyms=KOX16, ZNF359, ZNF612;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF24_HUMAN             Reviewed;         368 AA.
AC   P17028; O14754; Q53YE4; Q6ICR5; Q8IZN4;
DE   RecName: Full=Zinc finger protein 24;
DE   AltName: Full=Retinoic acid suppression protein A;
DE            Short=RSG-A;
DE   AltName: Full=Zinc finger and SCAN domain-containing protein 3;
DE   AltName: Full=Zinc finger protein 191;
DE   AltName: Full=Zinc finger protein KOX17;
GN   Name=ZNF24; Synonyms=KOX17, ZNF191, ZSCAN3;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0042552; P:myelination; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF25_HUMAN             Reviewed;         456 AA.
AC   P17030; A9Z1X5; Q8IYE3; Q8NDD6; Q96MU2;
DE   RecName: Full=Zinc finger protein 25;
DE   AltName: Full=Zinc finger protein KOX19;
GN   Name=ZNF25; Synonyms=KOX19;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF28_HUMAN             Reviewed;         718 AA.
AC   P17035; A8KAK9; B4E3G0; B9EIK7; Q5H9V1; Q5HYM9; Q6ZML9; Q6ZN56;
DE   RecName: Full=Zinc finger protein 28;
DE   AltName: Full=Zinc finger protein KOX24;
GN   Name=ZNF28; Synonyms=KOX24;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF26_HUMAN             Reviewed;         533 AA.
AC   P17031; Q86X57; Q9NWL3;
DE   RecName: Full=Zinc finger protein 26;
DE   AltName: Full=Zinc finger protein KOX20;
GN   Name=ZNF26; Synonyms=KOX20;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF2_HUMAN              Reviewed;         426 AA.
AC   Q9BSG1; A8MWV7; B4DIR4; Q4ZFY6; Q96G44; Q9UMC5;
DE   RecName: Full=Zinc finger protein 2;
DE   AltName: Full=Zinc finger protein 2.2;
DE   AltName: Full=Zinc finger protein 661;
GN   Name=ZNF2; Synonyms=ZNF661;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF30_HUMAN             Reviewed;         623 AA.
AC   P17039; A5PLP1; A8K320; B4DIC0; Q6N068;
DE   RecName: Full=Zinc finger protein 30;
DE   AltName: Full=Zinc finger protein KOX28;
GN   Name=ZNF30; Synonyms=KOX28;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF32_HUMAN             Reviewed;         273 AA.
AC   P17041; Q92951;
DE   RecName: Full=Zinc finger protein 32;
DE   AltName: Full=C2H2-546;
DE   AltName: Full=Zinc finger protein KOX30;
GN   Name=ZNF32; Synonyms=KOX30;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF34_HUMAN             Reviewed;         560 AA.
AC   Q8IZ26; D3DWN1; Q9BSZ0;
DE   RecName: Full=Zinc finger protein 34;
DE   AltName: Full=Zinc finger protein KOX32;
GN   Name=ZNF34; Synonyms=KOX32;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF35_HUMAN             Reviewed;         527 AA.
AC   P13682; B2RBU6; Q53Y54; Q96D01;
DE   RecName: Full=Zinc finger protein 35;
DE   AltName: Full=Zinc finger protein HF.10;
GN   Name=ZNF35;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
DR   GO; GO:0071300; P:cellular response to retinoic acid; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:ProtInc.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF3_HUMAN              Reviewed;         446 AA.
AC   P17036; D6W5U0; P13683; Q9HBR4; Q9NNX8; Q9NXJ1; Q9UC15; Q9UC16;
DE   RecName: Full=Zinc finger protein 3;
DE   AltName: Full=Zinc finger protein HF.12;
DE   AltName: Full=Zinc finger protein HZF3.1;
DE   AltName: Full=Zinc finger protein KOX25;
GN   Name=ZNF3; Synonyms=KOX25;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0045321; P:leukocyte activation; NAS:UniProtKB.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF41_HUMAN             Reviewed;         821 AA.
AC   P51814; A8K1V6; B4DH01; Q96LE8; Q9UMC4; Q9UMV5; Q9UMV6; Q9UMV7;
AC   Q9UMV8; Q9UMV9; Q9UMW0; Q9UMW1;
DE   RecName: Full=Zinc finger protein 41;
GN   Name=ZNF41;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF43_HUMAN             Reviewed;         809 AA.
AC   P17038; A8K5N8; P28160; Q53XQ2; Q5H9T3; Q96DG1;
DE   RecName: Full=Zinc finger protein 43;
DE   AltName: Full=Zinc finger protein 39;
DE   AltName: Full=Zinc finger protein HTF6;
DE   AltName: Full=Zinc finger protein KOX27;
GN   Name=ZNF43; Synonyms=KOX27, ZNF39, ZNF39L1;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF44_HUMAN             Reviewed;         663 AA.
AC   P15621; B4DML9; B9EGJ5; B9ZVM2; P17018; Q9ULZ7;
DE   RecName: Full=Zinc finger protein 44;
DE   AltName: Full=Gonadotropin-inducible ovary transcription repressor 2;
DE            Short=GIOT-2;
DE   AltName: Full=Zinc finger protein 55;
DE   AltName: Full=Zinc finger protein 58;
DE   AltName: Full=Zinc finger protein KOX7;
GN   Name=ZNF44; Synonyms=GIOT2, KOX7, ZNF55, ZNF58;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF45_HUMAN             Reviewed;         682 AA.
AC   Q02386; P17016; P78472; Q9P1U9;
DE   RecName: Full=Zinc finger protein 45;
DE   AltName: Full=BRC1744;
DE   AltName: Full=Zinc finger protein 13;
DE   AltName: Full=Zinc finger protein KOX5;
GN   Name=ZNF45; Synonyms=KOX5, ZNF13;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0010467; P:gene expression; TAS:Reactome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
//
ID   ZNF48_HUMAN             Reviewed;         618 AA.
AC   Q96MX3; Q15920; Q4G0R3; Q69YP3; Q96IL9;
DE   RecName: Full=Zinc finger protein 48;
DE   AltName: Full=Zinc finger protein 553;
GN   Name=ZNF48; Synonyms=ZNF553;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF56_HUMAN             Reviewed;         161 AA.
AC   Q15929;
DE   RecName: Full=Putative zinc finger protein 56;
DE   AltName: Full=Putative zinc finger protein 742;
GN   Name=ZNF56; Synonyms=ZNF742;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF57_HUMAN             Reviewed;         555 AA.
AC   Q68EA5; Q8N6R9;
DE   RecName: Full=Zinc finger protein 57;
DE   AltName: Full=Zinc finger protein 424;
GN   Name=ZNF57; Synonyms=ZNF424;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF67_HUMAN             Reviewed;         193 AA.
AC   Q15940;
DE   RecName: Full=Putative zinc finger protein 726P1;
GN   Name=ZNF726P1; Synonyms=ZNF67, ZNF67P;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
//
ID   ZNF66_HUMAN             Reviewed;         573 AA.
AC   Q6ZN08; I3L4P5; Q15939;
DE   RecName: Full=Putative zinc finger protein 66;
DE   AltName: Full=Zinc finger protein 66 pseudogene;
GN   Name=ZNF66; Synonyms=ZNF66P;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF69_HUMAN             Reviewed;         566 AA.
AC   Q9UC07; Q86VA7;
DE   RecName: Full=Zinc finger protein 69;
DE   AltName: Full=hZNF3;
GN   Name=ZNF69;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF70_HUMAN             Reviewed;         446 AA.
AC   Q9UC06;
DE   RecName: Full=Zinc finger protein 70;
DE   AltName: Full=Zinc finger protein N27C7-1;
GN   Name=ZNF70;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF71_HUMAN             Reviewed;         489 AA.
AC   Q9NQZ8; Q15919; Q9UC09; Q9UQD3;
DE   RecName: Full=Endothelial zinc finger protein induced by tumor necrosis factor alpha;
DE   AltName: Full=Zinc finger protein 71;
GN   Name=ZNF71; Synonyms=EZFIT;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF73_HUMAN             Reviewed;         326 AA.
AC   O43830; Q9UC08;
DE   RecName: Full=Zinc finger protein 73;
DE   AltName: Full=Zinc finger protein 186;
DE   AltName: Full=hZNF2;
GN   Name=ZNF73; Synonyms=ZNF186;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF74_HUMAN             Reviewed;         644 AA.
AC   Q16587; B5MCE3; B7Z5Y2; Q6IBV2; Q6PJP1; Q9UC04; Q9UF05; Q9UF06;
AC   Q9UF07;
DE   RecName: Full=Zinc finger protein 74;
DE   AltName: Full=Zinc finger protein 520;
DE   AltName: Full=hZNF7;
GN   Name=ZNF74; Synonyms=ZNF520;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF76_HUMAN             Reviewed;         570 AA.
AC   P36508; Q9BQB2;
DE   RecName: Full=Zinc finger protein 76;
DE   AltName: Full=Zinc finger protein 523;
GN   Name=ZNF76; Synonyms=D6S229E, ZNF523;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.
DR   GO; GO:0006359; P:regulation of transcription from RNA polymerase III promoter; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF79_HUMAN             Reviewed;         498 AA.
AC   Q15937; Q5VVW1; Q96NV1;
DE   RecName: Full=Zinc finger protein 79;
DE   AltName: Full=ZNFpT7;
GN   Name=ZNF79;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF77_HUMAN             Reviewed;         545 AA.
AC   Q15935; Q86XJ3; Q9NPP0;
DE   RecName: Full=Zinc finger protein 77;
DE   AltName: Full=ZNFpT1;
GN   Name=ZNF77;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF7_HUMAN              Reviewed;         686 AA.
AC   P17097; B4DT08; D3DWN6; P17015; Q8N8Y4;
DE   RecName: Full=Zinc finger protein 7;
DE   AltName: Full=Zinc finger protein HF.16;
DE   AltName: Full=Zinc finger protein KOX4;
GN   Name=ZNF7; Synonyms=KOX4;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0007275; P:multicellular organismal development; TAS:ProtInc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF80_HUMAN             Reviewed;         273 AA.
AC   P51504; Q6NSW4; Q6NT14;
DE   RecName: Full=Zinc finger protein 80;
DE   AltName: Full=ZNFpT17;
GN   Name=ZNF80;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF81_HUMAN             Reviewed;         661 AA.
AC   P51508; Q6RX22; Q96QH6;
DE   RecName: Full=Zinc finger protein 81;
DE   AltName: Full=HFZ20;
GN   Name=ZNF81;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF84_HUMAN             Reviewed;         738 AA.
AC   P51523; B2RAK5; D3DXJ1; Q3ZCV9; Q5D057; Q86XU8; Q9NNX7; Q9UC17;
AC   Q9UC18;
DE   RecName: Full=Zinc finger protein 84;
DE   AltName: Full=Zinc finger protein HPF2;
GN   Name=ZNF84;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF83_HUMAN             Reviewed;         516 AA.
AC   P51522; A8MT75; Q3ZCX0; Q6PI08;
DE   RecName: Full=Zinc finger protein 83;
DE   AltName: Full=Zinc finger protein 816B;
DE   AltName: Full=Zinc finger protein HPF1;
GN   Name=ZNF83; Synonyms=ZNF816B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF8_HUMAN              Reviewed;         575 AA.
AC   P17098; Q6PI99;
DE   RecName: Full=Zinc finger protein 8;
DE   AltName: Full=Zinc finger protein HF.18;
GN   Name=ZNF8;
DR   GO; GO:0003677; F:DNA binding; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF85_HUMAN             Reviewed;         595 AA.
AC   Q03923; B9ZVP4; Q6NVI0;
DE   RecName: Full=Zinc finger protein 85;
DE   AltName: Full=Zinc finger protein HPF4;
DE   AltName: Full=Zinc finger protein HTF1;
GN   Name=ZNF85;
DR   GO; GO:0003677; F:DNA binding; TAS:ProtInc.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF90_HUMAN             Reviewed;         601 AA.
AC   Q03938; B9EH87;
DE   RecName: Full=Zinc finger protein 90;
DE   AltName: Full=Zinc finger protein HTF9;
GN   Name=ZNF90;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF91_HUMAN             Reviewed;        1191 AA.
AC   Q05481; A8K5E1; B7Z6G6;
DE   RecName: Full=Zinc finger protein 91;
DE   AltName: Full=Zinc finger protein HPF7;
DE   AltName: Full=Zinc finger protein HTF10;
GN   Name=ZNF91;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF92_HUMAN             Reviewed;         586 AA.
AC   Q03936; A6NNF9; Q8N492; Q8NB35;
DE   RecName: Full=Zinc finger protein 92;
DE   AltName: Full=Zinc finger protein HTF12;
GN   Name=ZNF92;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF93_HUMAN             Reviewed;         620 AA.
AC   P35789; A6NMY2; B9EGT2; Q8N8Q4; Q9H9X5; Q9Y2N8;
DE   RecName: Full=Zinc finger protein 93;
DE   AltName: Full=Zinc finger protein 505;
DE   AltName: Full=Zinc finger protein HTF34;
GN   Name=ZNF93; Synonyms=ZNF505;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF98_HUMAN             Reviewed;         572 AA.
AC   A6NK75;
DE   RecName: Full=Zinc finger protein 98;
DE   AltName: Full=Zinc finger protein 739;
DE   AltName: Full=Zinc finger protein F7175;
GN   Name=ZNF98; Synonyms=ZNF739;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNF99_HUMAN             Reviewed;         864 AA.
AC   A8MXY4; M0R335;
DE   RecName: Full=Zinc finger protein 99;
GN   Name=ZNF99; Synonyms=C19orf9;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZNFS1_HUMAN             Reviewed;         211 AA.
AC   Q0IIN9; Q8NAE8;
DE   RecName: Full=Putative uncharacterized protein ZNF252P-AS1;
DE   AltName: Full=ZNF252P antisense RNA 1;
DE   AltName: Full=ZNF252P antisense gene protein 1;
GN   Name=ZNF252P-AS1; Synonyms=C8orf77;
//
ID   ZNFX1_HUMAN             Reviewed;        1918 AA.
AC   Q9P2E3; Q9BQM7; Q9BQM8; Q9H8C1; Q9H9S2; Q9NUM1; Q9NWW1;
DE   RecName: Full=NFX1-type zinc finger-containing protein 1;
GN   Name=ZNFX1; Synonyms=KIAA1404;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
//
ID   ZNHI2_HUMAN             Reviewed;         403 AA.
AC   Q9UHR6; Q3SY14; Q8IUV0;
DE   RecName: Full=Zinc finger HIT domain-containing protein 2;
DE   AltName: Full=Protein FON;
GN   Name=ZNHIT2; Synonyms=C11orf5;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZNHI1_HUMAN             Reviewed;         154 AA.
AC   O43257; Q6IB12;
DE   RecName: Full=Zinc finger HIT domain-containing protein 1;
DE   AltName: Full=Cyclin-G1-binding protein 1;
DE   AltName: Full=Zinc finger protein subfamily 4A member 1;
DE   AltName: Full=p18 Hamlet;
GN   Name=ZNHIT1; Synonyms=CGBP1, ZNFN4A1;
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0070317; P:negative regulation of G0 to G1 transition; IEA:Ensembl.
DR   GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0031063; P:regulation of histone deacetylation; IEA:Ensembl.
DR   GO; GO:0042129; P:regulation of T cell proliferation; IEA:Ensembl.
//
ID   ZNHI3_HUMAN             Reviewed;         155 AA.
AC   Q15649; A8K493; Q8WVJ3;
DE   RecName: Full=Zinc finger HIT domain-containing protein 3;
DE   AltName: Full=HNF-4a coactivator;
DE   AltName: Full=Thyroid hormone receptor interactor 3;
DE   AltName: Full=Thyroid receptor-interacting protein 3;
DE            Short=TR-interacting protein 3;
DE            Short=TRIP-3;
GN   Name=ZNHIT3; Synonyms=TRIP3;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046966; F:thyroid hormone receptor binding; TAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:UniProtKB.
//
ID   ZNRF1_HUMAN             Reviewed;         227 AA.
AC   Q8ND25; D3DUJ9; Q9H083;
DE   RecName: Full=E3 ubiquitin-protein ligase ZNRF1;
DE            EC=6.3.2.-;
DE   AltName: Full=Nerve injury-induced gene 283 protein;
DE   AltName: Full=Zinc/RING finger protein 1;
GN   Name=ZNRF1; Synonyms=NIN283;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
//
ID   ZNRF2_HUMAN             Reviewed;         242 AA.
AC   Q8NHG8;
DE   RecName: Full=E3 ubiquitin-protein ligase ZNRF2;
DE            EC=6.3.2.-;
DE   AltName: Full=Protein Ells2;
DE   AltName: Full=RING finger protein 202;
DE   AltName: Full=Zinc/RING finger protein 2;
GN   Name=ZNRF2; Synonyms=RNF202;
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
//
ID   ZNRF3_HUMAN             Reviewed;         936 AA.
AC   Q9ULT6; B3KU18; Q6ICH1; Q6NTF8; Q8WU18;
DE   RecName: Full=E3 ubiquitin-protein ligase ZNRF3;
DE            EC=6.3.2.-;
DE   AltName: Full=RING finger protein 203;
DE   AltName: Full=Zinc/RING finger protein 3;
DE   Flags: Precursor;
GN   Name=ZNRF3; Synonyms=KIAA1133, RNF203;
DR   GO; GO:0005109; F:frizzled binding; IPI:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:2000051; P:negative regulation of non-canonical Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB.
DR   GO; GO:0072089; P:stem cell proliferation; ISS:UniProtKB.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
DR   GO; GO:0038018; P:Wnt receptor catabolic process; IMP:UniProtKB.
DR   GO; GO:0060071; P:Wnt signaling pathway, planar cell polarity pathway; IEA:Ensembl.
//
ID   ZNRF4_HUMAN             Reviewed;         429 AA.
AC   Q8WWF5; A8K886; O75866;
DE   RecName: Full=Zinc/RING finger protein 4;
DE   AltName: Full=RING finger protein 204;
DE   Flags: Precursor;
GN   Name=ZNRF4; Synonyms=RNF204;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZNT10_HUMAN             Reviewed;         485 AA.
AC   Q6XR72; Q49AL9; Q9NPW0;
DE   RecName: Full=Zinc transporter 10;
DE            Short=ZnT-10;
DE   AltName: Full=Solute carrier family 30 member 10;
GN   Name=SLC30A10; Synonyms=ZNT10, ZNT8;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   ZNT1_HUMAN              Reviewed;         507 AA.
AC   Q9Y6M5; Q0VAK9; Q9BZF6;
DE   RecName: Full=Zinc transporter 1;
DE            Short=ZnT-1;
DE   AltName: Full=Solute carrier family 30 member 1;
GN   Name=SLC30A1; Synonyms=ZNT1;
DR   GO; GO:0019855; F:calcium channel inhibitor activity; ISS:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProt.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0070574; P:cadmium ion transmembrane transport; ISS:BHF-UCL.
DR   GO; GO:0070509; P:calcium ion import; IEA:Ensembl.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0071585; P:detoxification of cadmium ion; IEA:Ensembl.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0090281; P:negative regulation of calcium ion import; ISS:BHF-UCL.
DR   GO; GO:0046929; P:negative regulation of neurotransmitter secretion; ISS:BHF-UCL.
DR   GO; GO:0071584; P:negative regulation of zinc ion transmembrane import; ISS:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; ISS:BHF-UCL.
//
ID   ZNT2_HUMAN              Reviewed;         323 AA.
AC   Q9BRI3; Q71RC8;
DE   RecName: Full=Zinc transporter 2;
DE            Short=ZnT-2;
DE   AltName: Full=Solute carrier family 30 member 2;
GN   Name=SLC30A2; Synonyms=ZNT2;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0061090; P:positive regulation of sequestering of zinc ion; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   ZNT3_HUMAN              Reviewed;         388 AA.
AC   Q99726; Q8TC03;
DE   RecName: Full=Zinc transporter 3;
DE            Short=ZnT-3;
DE   AltName: Full=Solute carrier family 30 member 3;
GN   Name=SLC30A3; Synonyms=ZNT3;
DR   GO; GO:0015633; F:zinc transporting ATPase activity; TAS:ProtInc.
DR   GO; GO:0051050; P:positive regulation of transport; IEA:Ensembl.
DR   GO; GO:0061088; P:regulation of sequestering of zinc ion; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006810; P:transport; TAS:ProtInc.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; TAS:GOC.
//
ID   ZNT4_HUMAN              Reviewed;         429 AA.
AC   O14863; Q8TC39;
DE   RecName: Full=Zinc transporter 4;
DE            Short=ZnT-4;
DE   AltName: Full=Solute carrier family 30 member 4;
GN   Name=SLC30A4; Synonyms=ZNT4;
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; TAS:ProtInc.
DR   GO; GO:0061088; P:regulation of sequestering of zinc ion; IDA:BHF-UCL.
DR   GO; GO:0009636; P:response to toxic substance; IDA:UniProtKB.
DR   GO; GO:0055069; P:zinc ion homeostasis; IEA:Ensembl.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; TAS:GOC.
//
ID   ZNT5_HUMAN              Reviewed;         765 AA.
AC   Q8TAD4; B7ZM89; Q6UX54; Q7L4M4; Q8TDG3; Q9BVY8; Q9H9H1;
DE   RecName: Full=Zinc transporter 5;
DE            Short=ZnT-5;
DE   AltName: Full=Solute carrier family 30 member 5;
DE   AltName: Full=ZnT-like transporter 1;
DE            Short=hZTL1;
GN   Name=SLC30A5; Synonyms=ZNT5, ZNTL1, ZTL1; ORFNames=UNQ863/PRO1879;
DR   GO; GO:0008270; F:zinc ion binding; NAS:UniProtKB.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IDA:UniProtKB.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IDA:UniProtKB.
DR   GO; GO:0006824; P:cobalt ion transport; IDA:MGI.
DR   GO; GO:0010155; P:regulation of proton transport; NAS:UniProtKB.
DR   GO; GO:0010043; P:response to zinc ion; IDA:UniProtKB.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006829; P:zinc ion transport; IDA:UniProtKB.
//
ID   ZNT6_HUMAN              Reviewed;         461 AA.
AC   Q6NXT4; A5YM45; B7Z901; Q8N5C9; Q96NC3;
DE   RecName: Full=Zinc transporter 6;
DE            Short=ZnT-6;
DE   AltName: Full=Solute carrier family 30 member 6;
GN   Name=SLC30A6; Synonyms=ZNT6;
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Ensembl.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0006895; P:Golgi to endosome transport; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
//
ID   ZNT7_HUMAN              Reviewed;         376 AA.
AC   Q8NEW0; B2R949; D3DT61; Q8TCH2;
DE   RecName: Full=Zinc transporter 7;
DE            Short=ZnT-7;
DE   AltName: Full=Solute carrier family 30 member 7;
DE   AltName: Full=Znt-like transporter 2;
GN   Name=SLC30A7; Synonyms=ZNT7, ZNTL2;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
DR   GO; GO:0032119; P:sequestering of zinc ion; IEA:Ensembl.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   ZNT8_HUMAN              Reviewed;         369 AA.
AC   Q8IWU4; A0AVP9; A5YM39; B4DPE0; Q8TCL3;
DE   RecName: Full=Zinc transporter 8;
DE            Short=ZnT-8;
DE   AltName: Full=Solute carrier family 30 member 8;
GN   Name=SLC30A8; Synonyms=ZNT8;
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.
DR   GO; GO:0008270; F:zinc ion binding; IC:BHF-UCL.
DR   GO; GO:0005385; F:zinc ion transmembrane transporter activity; IDA:BHF-UCL.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; ISS:BHF-UCL.
DR   GO; GO:0030073; P:insulin secretion; IMP:BHF-UCL.
DR   GO; GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL.
DR   GO; GO:0061088; P:regulation of sequestering of zinc ion; ISS:BHF-UCL.
DR   GO; GO:0060627; P:regulation of vesicle-mediated transport; ISS:BHF-UCL.
DR   GO; GO:0009749; P:response to glucose; IMP:BHF-UCL.
DR   GO; GO:0034341; P:response to interferon-gamma; IEA:Ensembl.
DR   GO; GO:0070555; P:response to interleukin-1; IEA:Ensembl.
DR   GO; GO:0032119; P:sequestering of zinc ion; IDA:BHF-UCL.
DR   GO; GO:0055085; P:transmembrane transport; TAS:Reactome.
DR   GO; GO:0071577; P:zinc ion transmembrane transport; IDA:GOC.
DR   GO; GO:0006829; P:zinc ion transport; IDA:BHF-UCL.
//
ID   ZNT9_HUMAN              Reviewed;         568 AA.
AC   Q6PML9; Q4W5B6; Q7Z5I7; Q8TBB2; Q9Y6R2;
DE   RecName: Full=Zinc transporter 9;
DE            Short=ZnT-9;
DE   AltName: Full=Human embryonic lung protein;
DE            Short=HuEL;
DE   AltName: Full=Solute carrier family 30 member 9;
GN   Name=SLC30A9; Synonyms=C4orf1, HUEL;
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IEA:Ensembl.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006289; P:nucleotide-excision repair; TAS:BHF-UCL.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW.
//
ID   ZO1_HUMAN               Reviewed;        1748 AA.
AC   Q07157; B4E3K1; Q2NKP3; Q4ZGJ6;
DE   RecName: Full=Tight junction protein ZO-1;
DE   AltName: Full=Tight junction protein 1;
DE   AltName: Full=Zona occludens protein 1;
DE   AltName: Full=Zonula occludens protein 1;
GN   Name=TJP1; Synonyms=ZO1;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0001825; P:blastocyst formation; IEA:Ensembl.
DR   GO; GO:0007043; P:cell-cell junction assembly; TAS:ProtInc.
DR   GO; GO:1901350; P:cell-cell signaling involved in cell-cell junction organization; NAS:UniProtKB.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0061024; P:membrane organization; TAS:Reactome.
DR   GO; GO:0043116; P:negative regulation of vascular permeability; IEA:Ensembl.
DR   GO; GO:0042493; P:response to drug; IEA:Ensembl.
DR   GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
DR   GO; GO:0032496; P:response to lipopolysaccharide; IEA:Ensembl.
DR   GO; GO:0071000; P:response to magnetism; IEA:Ensembl.
//
ID   ZO2_HUMAN               Reviewed;        1190 AA.
AC   Q9UDY2; A2A3H9; B7Z2R8; B7Z7T6; F5H301; F5H886; Q15883; Q5VXL0;
AC   Q5VXL1; Q8N756; Q8NI14; Q99839; Q9UDY0; Q9UDY1;
DE   RecName: Full=Tight junction protein ZO-2;
DE   AltName: Full=Tight junction protein 2;
DE   AltName: Full=Zona occludens protein 2;
DE   AltName: Full=Zonula occludens protein 2;
GN   Name=TJP2; Synonyms=X104, ZO2;
DR   GO; GO:0004385; F:guanylate kinase activity; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006915; P:apoptotic process; TAS:Reactome.
DR   GO; GO:0006921; P:cellular component disassembly involved in execution phase of apoptosis; TAS:Reactome.
DR   GO; GO:0035329; P:hippo signaling; TAS:Reactome.
DR   GO; GO:0046939; P:nucleotide phosphorylation; TAS:GOC.
DR   GO; GO:0010033; P:response to organic substance; IEA:Ensembl.
//
ID   ZO3_HUMAN               Reviewed;         919 AA.
AC   O95049; A6NFP3; B3KR73; B3KXZ0; B4E2W6; F5H2X0; F5H4S9; K7EK22;
AC   Q32N01;
DE   RecName: Full=Tight junction protein ZO-3;
DE   AltName: Full=Tight junction protein 3;
DE   AltName: Full=Zona occludens protein 3;
DE   AltName: Full=Zonula occludens protein 3;
GN   Name=TJP3; Synonyms=ZO3;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
//
ID   ZP1_HUMAN               Reviewed;         638 AA.
AC   P60852;
DE   RecName: Full=Zona pellucida sperm-binding protein 1;
DE   AltName: Full=Zona pellucida glycoprotein 1;
DE            Short=Zp-1;
DE   Contains:
DE     RecName: Full=Processed zona pellucida sperm-binding protein 1;
DE   Flags: Precursor;
GN   Name=ZP1;
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ZP2_HUMAN               Reviewed;         745 AA.
AC   Q05996; B2R7J2; Q4VAN9; Q4VAP0; Q4VAP1;
DE   RecName: Full=Zona pellucida sperm-binding protein 2;
DE   AltName: Full=Zona pellucida glycoprotein 2;
DE            Short=Zp-2;
DE   AltName: Full=Zona pellucida protein A;
DE   Contains:
DE     RecName: Full=Processed zona pellucida sperm-binding protein 2;
DE   Flags: Precursor;
GN   Name=ZP2; Synonyms=ZPA;
DR   GO; GO:0032190; F:acrosin binding; IPI:UniProtKB.
DR   GO; GO:0015026; F:coreceptor activity; TAS:ProtInc.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:0060468; P:prevention of polyspermy; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:GOC.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ZP3_HUMAN               Reviewed;         424 AA.
AC   P21754; Q06633; Q29RW0;
DE   RecName: Full=Zona pellucida sperm-binding protein 3;
DE   AltName: Full=Sperm receptor;
DE   AltName: Full=ZP3A/ZP3B;
DE   AltName: Full=Zona pellucida glycoprotein 3;
DE            Short=Zp-3;
DE   AltName: Full=Zona pellucida protein C;
DE   Contains:
DE     RecName: Full=Processed zona pellucida sperm-binding protein 3;
DE   Flags: Precursor;
GN   Name=ZP3; Synonyms=ZP3A, ZP3B, ZPC;
DR   GO; GO:0032190; F:acrosin binding; IPI:UniProtKB.
DR   GO; GO:0030246; F:carbohydrate binding; IDA:UniProtKB.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; ISS:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IDA:UniProtKB.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IDA:UniProtKB.
DR   GO; GO:0001825; P:blastocyst formation; ISS:UniProtKB.
DR   GO; GO:0070588; P:calcium ion transmembrane transport; IDA:GOC.
DR   GO; GO:0035803; P:egg coat formation; ISS:UniProtKB.
DR   GO; GO:0002455; P:humoral immune response mediated by circulating immunoglobulin; ISS:UniProtKB.
DR   GO; GO:0006886; P:intracellular protein transport; ISS:UniProtKB.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:UniProtKB.
DR   GO; GO:0071421; P:manganese ion transmembrane transport; ISS:GOC.
DR   GO; GO:0006828; P:manganese ion transport; ISS:UniProtKB.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:2000360; P:negative regulation of binding of sperm to zona pellucida; IDA:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0048599; P:oocyte development; ISS:UniProtKB.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.
DR   GO; GO:2000368; P:positive regulation of acrosomal vesicle exocytosis; IDA:UniProtKB.
DR   GO; GO:2000344; P:positive regulation of acrosome reaction; IDA:UniProtKB.
DR   GO; GO:2000388; P:positive regulation of antral ovarian follicle growth; ISS:UniProtKB.
DR   GO; GO:0090280; P:positive regulation of calcium ion import; IDA:UniProtKB.
DR   GO; GO:0002922; P:positive regulation of humoral immune response; IDA:UniProtKB.
DR   GO; GO:0050729; P:positive regulation of inflammatory response; ISS:UniProtKB.
DR   GO; GO:0032729; P:positive regulation of interferon-gamma production; ISS:UniProtKB.
DR   GO; GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.
DR   GO; GO:0002687; P:positive regulation of leukocyte migration; ISS:UniProtKB.
DR   GO; GO:2000386; P:positive regulation of ovarian follicle development; ISS:UniProtKB.
DR   GO; GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; ISS:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0051897; P:positive regulation of protein kinase B signaling; ISS:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0001809; P:positive regulation of type IV hypersensitivity; ISS:UniProtKB.
DR   GO; GO:0070528; P:protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ZP4_HUMAN               Reviewed;         540 AA.
AC   Q12836; B2RAE1;
DE   RecName: Full=Zona pellucida sperm-binding protein 4;
DE   AltName: Full=Zona pellucida glycoprotein 4;
DE            Short=Zp-4;
DE   AltName: Full=Zona pellucida protein B;
DE   Contains:
DE     RecName: Full=Processed zona pellucida sperm-binding protein 4;
DE   Flags: Precursor;
GN   Name=ZP4; Synonyms=ZPB;
DR   GO; GO:0032190; F:acrosin binding; IPI:UniProtKB.
DR   GO; GO:0004871; F:signal transducer activity; IMP:UniProtKB.
DR   GO; GO:0060478; P:acrosomal vesicle exocytosis; IMP:UniProtKB.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; TAS:Reactome.
DR   GO; GO:0035556; P:intracellular signal transduction; IMP:UniProtKB.
DR   GO; GO:0032504; P:multicellular organism reproduction; TAS:Reactome.
DR   GO; GO:2000360; P:negative regulation of binding of sperm to zona pellucida; IDA:UniProtKB.
DR   GO; GO:2000344; P:positive regulation of acrosome reaction; IDA:UniProtKB.
DR   GO; GO:0002922; P:positive regulation of humoral immune response; IDA:UniProtKB.
DR   GO; GO:0045860; P:positive regulation of protein kinase activity; IDA:UniProtKB.
DR   GO; GO:0042102; P:positive regulation of T cell proliferation; IDA:UniProtKB.
DR   GO; GO:0010737; P:protein kinase A signaling; IDA:UniProtKB.
DR   GO; GO:0070528; P:protein kinase C signaling; IMP:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; TAS:Reactome.
//
ID   ZPBP1_HUMAN             Reviewed;         351 AA.
AC   Q9BS86; A4D253; C9JPU1; Q15941; Q75KX9; Q75MI3;
DE   RecName: Full=Zona pellucida-binding protein 1;
DE   AltName: Full=Sp38;
DE   Flags: Precursor;
GN   Name=ZPBP; Synonyms=ZPBP1;
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
//
ID   ZPBP2_HUMAN             Reviewed;         338 AA.
AC   Q6X784; A8K8L8; Q6X783; Q86XL5;
DE   RecName: Full=Zona pellucida-binding protein 2;
DE   AltName: Full=ZPBP-like protein;
DE   Flags: Precursor;
GN   Name=ZPBP2; Synonyms=ZPBPL;
DR   GO; GO:0001675; P:acrosome assembly; IEA:Ensembl.
DR   GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
//
ID   ZPI_HUMAN               Reviewed;         444 AA.
AC   Q9UK55; A5Z2A5; Q6UWX9; Q86U20;
DE   RecName: Full=Protein Z-dependent protease inhibitor;
DE            Short=PZ-dependent protease inhibitor;
DE            Short=PZI;
DE   AltName: Full=Serpin A10;
DE   Flags: Precursor;
GN   Name=SERPINA10; Synonyms=ZPI; ORFNames=UNQ707/PRO1358;
DR   GO; GO:0008201; F:heparin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:RefGenome.
DR   GO; GO:0007596; P:blood coagulation; IEA:UniProtKB-KW.
DR   GO; GO:0010951; P:negative regulation of endopeptidase activity; IBA:RefGenome.
DR   GO; GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
//
ID   ZPLD1_HUMAN             Reviewed;         415 AA.
AC   Q8TCW7; Q49AS1; Q8WU36;
DE   RecName: Full=Zona pellucida-like domain-containing protein 1;
DE            Short=ZP domain-containing protein 1;
DE   Flags: Precursor;
GN   Name=ZPLD1;
//
ID   ZPR1_HUMAN              Reviewed;         459 AA.
AC   O75312; Q2TAA0;
DE   RecName: Full=Zinc finger protein ZPR1;
DE   AltName: Full=Zinc finger protein 259;
GN   Name=ZPR1; Synonyms=ZNF259;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0031369; F:translation initiation factor binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR   GO; GO:1902742; P:apoptotic process involved in development; ISS:UniProtKB.
DR   GO; GO:0061564; P:axon development; IMP:UniProtKB.
DR   GO; GO:0030576; P:Cajal body organization; IMP:UniProtKB.
DR   GO; GO:0008283; P:cell proliferation; TAS:ProtInc.
DR   GO; GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.
DR   GO; GO:0042023; P:DNA endoreduplication; ISS:UniProtKB.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; ISS:UniProtKB.
DR   GO; GO:2000672; P:negative regulation of motor neuron apoptotic process; ISS:UniProtKB.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.
DR   GO; GO:0045927; P:positive regulation of growth; ISS:UniProtKB.
DR   GO; GO:0042307; P:positive regulation of protein import into nucleus; IDA:UniProtKB.
DR   GO; GO:0033120; P:positive regulation of RNA splicing; IMP:UniProtKB.
DR   GO; GO:0071931; P:positive regulation of transcription involved in G1/S transition of mitotic cell cycle; IMP:UniProtKB.
DR   GO; GO:1990261; P:pre-mRNA catabolic process; IMP:UniProtKB.
DR   GO; GO:0031641; P:regulation of myelination; ISS:UniProtKB.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0021510; P:spinal cord development; ISS:UniProtKB.
DR   GO; GO:0001834; P:trophectodermal cell proliferation; ISS:UniProtKB.
//
ID   ZRAB2_HUMAN             Reviewed;         330 AA.
AC   O95218; D3DQ75; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63;
DE   RecName: Full=Zinc finger Ran-binding domain-containing protein 2;
DE   AltName: Full=Zinc finger protein 265;
DE   AltName: Full=Zinc finger, splicing;
GN   Name=ZRANB2; Synonyms=ZIS, ZNF265;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0003723; F:RNA binding; TAS:ProtInc.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:GOC.
DR   GO; GO:0008380; P:RNA splicing; TAS:ProtInc.
//
ID   ZRAB3_HUMAN             Reviewed;        1079 AA.
AC   Q5FWF4; B3KYA1; B4E375; B5MDI3; D3DP76; E9PBP0; Q53SM1; Q6P2C4;
AC   Q8N1P4; Q9H0E8;
DE   RecName: Full=DNA annealing helicase and endonuclease ZRANB3;
DE   AltName: Full=Annealing helicase 2;
DE            Short=AH2;
DE   AltName: Full=Zinc finger Ran-binding domain-containing protein 3;
DE   Includes:
DE     RecName: Full=DNA annealing helicase ZRANB3;
DE              EC=3.6.4.-;
DE   Includes:
DE     RecName: Full=Endonuclease ZRANB3;
DE              EC=3.1.-.-;
GN   Name=ZRANB3;
DR   GO; GO:0036310; F:annealing helicase activity; IDA:UniProtKB.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004520; F:endodeoxyribonuclease activity; IDA:UniProtKB.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IDA:UniProtKB.
DR   GO; GO:0000737; P:DNA catabolic process, endonucleolytic; IDA:GOC.
DR   GO; GO:0006281; P:DNA repair; IDA:UniProtKB.
DR   GO; GO:0036292; P:DNA rewinding; IDA:UniProtKB.
DR   GO; GO:0000733; P:DNA strand renaturation; IDA:GOC.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IDA:UniProtKB.
DR   GO; GO:0031297; P:replication fork processing; IDA:UniProtKB.
DR   GO; GO:0048478; P:replication fork protection; IDA:UniProtKB.
DR   GO; GO:0009411; P:response to UV; IDA:UniProtKB.
//
ID   ZRAN1_HUMAN             Reviewed;         708 AA.
AC   Q9UGI0; B4DZ98; D3DRF4; Q5SQP6; Q69YK3;
DE   RecName: Full=Ubiquitin thioesterase ZRANB1;
DE            EC=3.4.19.12;
DE   AltName: Full=TRAF-binding domain-containing protein;
DE            Short=hTrabid;
DE   AltName: Full=Zinc finger Ran-binding domain-containing protein 1;
GN   Name=ZRANB1; Synonyms=TRABID;
DR   GO; GO:0070530; F:K63-linked polyubiquitin binding; IDA:BHF-UCL.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
DR   GO; GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016477; P:cell migration; IMP:UniProtKB.
DR   GO; GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.
DR   GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IMP:UniProtKB.
DR   GO; GO:0071947; P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:BHF-UCL.
DR   GO; GO:0035523; P:protein K29-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:1990168; P:protein K33-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.
DR   GO; GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
//
ID   ZRAS1_HUMAN             Reviewed;         187 AA.
AC   Q2KJ03;
DE   RecName: Full=Putative uncharacterized protein ZNRD1-AS1;
DE   AltName: Full=Protein HTEX4;
DE   AltName: Full=ZNRD1 antisense RNA 1;
DE   AltName: Full=ZNRD1 antisense gene protein 1;
GN   Name=ZNRD1-AS1; Synonyms=C6orf12, HTEX4, NCRNA00171;
//
ID   ZSA5A_HUMAN             Reviewed;         496 AA.
AC   Q9BUG6; Q49A73; Q53F04; Q8N7B3;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 5A;
DE   AltName: Full=Zinc finger protein 495;
GN   Name=ZSCAN5A; Synonyms=ZNF495, ZSCAN5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSA5B_HUMAN             Reviewed;         495 AA.
AC   A6NJL1;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 5B;
GN   Name=ZSCAN5B;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSA5D_HUMAN             Reviewed;         497 AA.
AC   P0CG00;
DE   RecName: Full=Putative zinc finger and SCAN domain-containing protein 5D;
GN   Name=ZSCAN5D;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC10_HUMAN             Reviewed;         725 AA.
AC   Q96SZ4; B3KQD3; H0YFS6; Q1WWM2;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 10;
DE   AltName: Full=Zinc finger protein 206;
GN   Name=ZSCAN10; Synonyms=ZNF206;
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:RefGenome.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSA5C_HUMAN             Reviewed;         496 AA.
AC   A6NGD5;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 5C;
GN   Name=ZSCAN5C;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSC12_HUMAN             Reviewed;         604 AA.
AC   O43309; O43724;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 12;
DE   AltName: Full=Zinc finger protein 305;
DE   AltName: Full=Zinc finger protein 96;
GN   Name=ZSCAN12; Synonyms=KIAA0426, ZNF305, ZNF96;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC16_HUMAN             Reviewed;         348 AA.
AC   Q9H4T2; Q9H6K2;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 16;
DE   AltName: Full=Zinc finger protein 392;
DE   AltName: Full=Zinc finger protein 435;
GN   Name=ZSCAN16; Synonyms=ZNF392, ZNF435;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC20_HUMAN             Reviewed;        1043 AA.
AC   P17040; A8K2D0; B1ALI4; B1ALI5; B1ALI6; Q6ZN23; Q96FA9; Q96H84;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 20;
DE   AltName: Full=Zinc finger protein 31;
DE   AltName: Full=Zinc finger protein 360;
DE   AltName: Full=Zinc finger protein KOX29;
GN   Name=ZSCAN20; Synonyms=KOX29, ZNF31, ZNF360;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC18_HUMAN             Reviewed;         510 AA.
AC   Q8TBC5; B4DG23; E9PBI0; Q9BRK7; Q9H9A0;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 18;
DE   AltName: Full=Zinc finger protein 447;
GN   Name=ZSCAN18; Synonyms=ZNF447;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSC21_HUMAN             Reviewed;         473 AA.
AC   Q9Y5A6; A4D2A6; D6W5T9; Q9H0B5;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 21;
DE   AltName: Full=Renal carcinoma antigen NY-REN-21;
DE   AltName: Full=Zinc finger protein 38 homolog;
DE            Short=Zfp-38;
GN   Name=ZSCAN21; Synonyms=ZFP38, ZNF38;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC23_HUMAN             Reviewed;         389 AA.
AC   Q3MJ62; Q96KV9;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 23;
DE   AltName: Full=Zinc finger protein 390;
DE   AltName: Full=Zinc finger protein 453;
GN   Name=ZSCAN23; Synonyms=ZNF390, ZNF453;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC22_HUMAN             Reviewed;         491 AA.
AC   P10073; Q15922; Q7Z3L8;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 22;
DE   AltName: Full=Krueppel-related zinc finger protein 2;
DE   AltName: Full=Protein HKR2;
DE   AltName: Full=Zinc finger protein 50;
GN   Name=ZSCAN22; Synonyms=HKR2, ZNF50;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC25_HUMAN             Reviewed;         544 AA.
AC   Q6NSZ9; A4D290; D6W5T5; Q14C82; Q14C99; Q5EBM9; Q6DJZ0; Q6N032;
AC   Q6ZML3;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 25;
DE   AltName: Full=Zinc finger protein 498;
GN   Name=ZSCAN25; Synonyms=ZNF498;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC26_HUMAN             Reviewed;         478 AA.
AC   Q16670; Q5JPG4; Q7Z3Q6; Q96A17;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 26;
DE   AltName: Full=Protein SRE-ZBP;
DE   AltName: Full=Zinc finger protein 187;
GN   Name=ZSCAN26; Synonyms=ZNF187;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; NAS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC29_HUMAN             Reviewed;         852 AA.
AC   Q8IWY8; B3KVB9; Q32M75; Q32M76; Q8NA40;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 29;
DE   AltName: Full=Zinc finger protein 690;
GN   Name=ZSCAN29; Synonyms=ZNF690;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSC30_HUMAN             Reviewed;         494 AA.
AC   Q86W11; B4E0N0; Q6ZNB3; Q96PN3;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 30;
DE   AltName: Full=ZNF-WYM;
DE   AltName: Full=Zinc finger protein 397 opposite strand;
DE   AltName: Full=Zinc finger protein 397OS;
GN   Name=ZSCAN30; Synonyms=ZNF397OS;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC31_HUMAN             Reviewed;         406 AA.
AC   Q96LW9; Q6P178; Q8WWS5;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 31;
DE   AltName: Full=Zinc finger protein 323;
GN   Name=ZSCAN31; Synonyms=ZNF310P, ZNF323;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC32_HUMAN             Reviewed;         697 AA.
AC   Q9NX65; Q6WMU8; Q7Z6G2; Q8NFX8; Q9BU74;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 32;
DE   AltName: Full=Human cervical cancer suppressor gene 5 protein;
DE            Short=HCCS-5;
DE   AltName: Full=Zinc finger protein 434;
GN   Name=ZSCAN32; Synonyms=ZNF434; ORFNames=HCCS5;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSCA2_HUMAN             Reviewed;         614 AA.
AC   Q7Z7L9; A6NG83; B2RMQ9; Q6ZQY9; Q9NWU4;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 2;
DE   AltName: Full=Zinc finger protein 29 homolog;
DE            Short=Zfp-29;
DE   AltName: Full=Zinc finger protein 854;
GN   Name=ZSCAN2; Synonyms=ZFP29, ZNF854;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSC9_HUMAN              Reviewed;         394 AA.
AC   O15535; B4E1W6; E7EVQ2; Q2TTR1;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 9;
DE   AltName: Full=Cell proliferation-inducing gene 12 protein;
DE   AltName: Full=PRD51;
DE   AltName: Full=Zinc finger protein 193;
GN   Name=ZSCAN9; Synonyms=ZNF193; ORFNames=PIG12;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSCA4_HUMAN             Reviewed;         433 AA.
AC   Q8NAM6; Q3MIQ2;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 4;
DE   AltName: Full=Zinc finger protein 494;
GN   Name=ZSCAN4; Synonyms=ZNF494;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0010833; P:telomere maintenance via telomere lengthening; ISS:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZSCA1_HUMAN             Reviewed;         408 AA.
AC   Q8NBB4; Q3B798; Q6WLH8; Q86WS8;
DE   RecName: Full=Zinc finger and SCAN domain-containing protein 1;
GN   Name=ZSCAN1;
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IBA:RefGenome.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:RefGenome.
DR   GO; GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IBA:GOC.
DR   GO; GO:0006366; P:transcription from RNA polymerase II promoter; IBA:GOC.
//
ID   ZSWM2_HUMAN             Reviewed;         633 AA.
AC   Q8NEG5; B3KXV6; Q53SI3; Q57ZY3;
DE   RecName: Full=E3 ubiquitin-protein ligase ZSWIM2;
DE            EC=6.3.2.-;
DE   AltName: Full=MEKK1-related protein X;
DE            Short=MEX;
DE   AltName: Full=ZZ-type zinc finger-containing protein 2;
DE   AltName: Full=Zinc finger SWIM domain-containing protein 2;
GN   Name=ZSWIM2; Synonyms=ZZZ2;
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:Ensembl.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
//
ID   ZSWM1_HUMAN             Reviewed;         485 AA.
AC   Q9BR11; Q5JZH2; Q9BR12; Q9BV30;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 1;
GN   Name=ZSWIM1; Synonyms=C20orf162;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZSWM3_HUMAN             Reviewed;         696 AA.
AC   Q96MP5; Q9BR13;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 3;
GN   Name=ZSWIM3; Synonyms=C20orf164;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZSWM4_HUMAN             Reviewed;         989 AA.
AC   Q9H7M6;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 4;
GN   Name=ZSWIM4;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZSWM6_HUMAN             Reviewed;        1215 AA.
AC   Q9HCJ5;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 6;
GN   Name=ZSWIM6; Synonyms=KIAA1577;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0048812; P:neuron projection morphogenesis; IEA:Ensembl.
DR   GO; GO:2001222; P:regulation of neuron migration; IEA:Ensembl.
//
ID   ZSWM5_HUMAN             Reviewed;        1185 AA.
AC   Q9P217; Q5SXQ9;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 5;
GN   Name=ZSWIM5; Synonyms=KIAA1511;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZSWM7_HUMAN             Reviewed;         140 AA.
AC   Q19AV6;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 7;
DE   AltName: Full=SWIM domain-containing and Srs2-interacting protein 1 homolog;
DE   AltName: Full=SWIM-type zinc finger domain-containing protein 7;
GN   Name=ZSWIM7; Synonyms=SWS1;
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.
DR   GO; GO:0050821; P:protein stabilization; IMP:UniProtKB.
//
ID   ZSWM8_HUMAN             Reviewed;        1837 AA.
AC   A7E2V4; B2RP37; O94987; Q17RS8; Q2TAB8; Q6P439; Q8IW81; Q8NB34;
AC   Q9H8F3;
DE   RecName: Full=Zinc finger SWIM domain-containing protein 8;
GN   Name=ZSWIM8; Synonyms=KIAA0913;
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZUFSP_HUMAN             Reviewed;         578 AA.
AC   Q96AP4; Q5TD92; Q6PJH7; Q96NV6;
DE   RecName: Full=Zinc finger with UFM1-specific peptidase domain protein;
GN   Name=ZUFSP; Synonyms=C6orf113;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
//
ID   ZWILC_HUMAN             Reviewed;         591 AA.
AC   Q9H900; B3KVB8; Q6N049; Q8N404; Q96SY7; Q9NWG7;
DE   RecName: Full=Protein zwilch homolog;
DE            Short=hZwilch;
GN   Name=ZWILCH;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.
//
ID   ZW10_HUMAN              Reviewed;         779 AA.
AC   O43264;
DE   RecName: Full=Centromere/kinetochore protein zw10 homolog;
GN   Name=ZW10;
DR   GO; GO:0019237; F:centromeric DNA binding; TAS:ProtInc.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:HGNC.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.
DR   GO; GO:0007126; P:meiotic nuclear division; TAS:ProtInc.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:UniProtKB.
DR   GO; GO:0007080; P:mitotic metaphase plate congression; IMP:UniProtKB.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IDA:HGNC.
DR   GO; GO:0006461; P:protein complex assembly; IDA:HGNC.
DR   GO; GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0007096; P:regulation of exit from mitosis; IDA:HGNC.
//
ID   ZWINT_HUMAN             Reviewed;         277 AA.
AC   O95229; A6NNV6; Q0D2I3; Q9BWD0;
DE   RecName: Full=ZW10 interactor;
DE   AltName: Full=ZW10-interacting protein 1;
DE            Short=Zwint-1;
GN   Name=ZWINT;
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:HGNC.
DR   GO; GO:0007049; P:cell cycle; NAS:UniProtKB.
DR   GO; GO:0051649; P:establishment of localization in cell; IDA:HGNC.
DR   GO; GO:0000278; P:mitotic cell cycle; TAS:Reactome.
DR   GO; GO:0007093; P:mitotic cell cycle checkpoint; IDA:HGNC.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IDA:HGNC.
DR   GO; GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.
DR   GO; GO:0007051; P:spindle organization; NAS:UniProtKB.
//
ID   ZXDA_HUMAN              Reviewed;         799 AA.
AC   P98168; Q9UJP7;
DE   RecName: Full=Zinc finger X-linked protein ZXDA;
GN   Name=ZXDA;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZXDB_HUMAN              Reviewed;         803 AA.
AC   P98169; A8K151; Q9UBB3;
DE   RecName: Full=Zinc finger X-linked protein ZXDB;
GN   Name=ZXDB;
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZXDC_HUMAN              Reviewed;         858 AA.
AC   Q2QGD7; C5J0H9; Q6DKI8; Q7L3L1; Q8NAU2;
DE   RecName: Full=Zinc finger protein ZXDC;
DE   AltName: Full=ZXD-like zinc finger protein;
GN   Name=ZXDC; Synonyms=ZXDL;
DR   GO; GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.
DR   GO; GO:0030275; F:LRR domain binding; IPI:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0005515; F:protein binding; IPI:UniProtKB.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//
ID   ZY11A_HUMAN             Reviewed;         759 AA.
AC   Q6WRX3; A6NCK5;
DE   RecName: Full=Protein zyg-11 homolog A;
GN   Name=ZYG11A; Synonyms=ZYG11;
//
ID   ZY11B_HUMAN             Reviewed;         744 AA.
AC   Q9C0D3; Q8N2X3; Q9H8L8;
DE   RecName: Full=Protein zyg-11 homolog B;
GN   Name=ZYG11B; Synonyms=KIAA1730;
//
ID   ZYX_HUMAN               Reviewed;         572 AA.
AC   Q15942; A4D2G6; Q6I9S4;
DE   RecName: Full=Zyxin;
DE   AltName: Full=Zyxin-2;
GN   Name=ZYX;
DR   GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; TAS:ProtInc.
DR   GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
DR   GO; GO:0050727; P:regulation of inflammatory response; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   GO; GO:0016032; P:viral process; IEA:UniProtKB-KW.
//
ID   ZZEF1_HUMAN             Reviewed;        2961 AA.
AC   O43149; A7MBM5; Q6NXG0; Q6ZRA1; Q6ZSF4; Q9NVB9;
DE   RecName: Full=Zinc finger ZZ-type and EF-hand domain-containing protein 1;
GN   Name=ZZEF1; Synonyms=KIAA0399;
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
//
ID   ZZZ3_HUMAN              Reviewed;         903 AA.
AC   Q8IYH5; B7WPC6; Q6N004; Q6N070; Q8IYP0; Q8IYR1; Q8TEK4; Q9Y4U0;
DE   RecName: Full=ZZ-type zinc finger-containing protein 3;
GN   Name=ZZZ3;
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005515; F:protein binding; IPI:IntAct.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; TAS:Reactome.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
//